Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000937-TA|BGIBMGA000937-PA|IPR000257|Uroporphyrinogen
decarboxylase (URO-D), IPR006361|Uroporphyrinogen decarboxylase HemE
(310 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AL359473-5|CAI16441.1| 227|Homo sapiens uroporphyrinogen decarb... 270 3e-72
CR542057-1|CAG46854.1| 367|Homo sapiens UROD protein. 198 2e-50
CR456976-1|CAG33257.1| 367|Homo sapiens UROD protein. 198 2e-50
BT006737-1|AAP35383.1| 367|Homo sapiens uroporphyrinogen decarb... 198 2e-50
BC001778-1|AAH01778.1| 367|Homo sapiens uroporphyrinogen decarb... 198 2e-50
AL359473-4|CAI16440.1| 367|Homo sapiens uroporphyrinogen decarb... 198 2e-50
AF047383-1|AAC03563.1| 367|Homo sapiens uroporphyrinogen decarb... 198 2e-50
X89267-1|CAA61540.1| 367|Homo sapiens uroporphyrinogen decarbox... 198 3e-50
U30787-1|AAC50482.1| 367|Homo sapiens uroporphyrinogen decarbox... 198 3e-50
AY292986-1|AAP44118.1| 367|Homo sapiens uroporphyrinogen decarb... 198 3e-50
AF104440-1|AAD04590.1| 367|Homo sapiens uroporphyrinogen decarb... 198 3e-50
AF104439-1|AAD04589.1| 367|Homo sapiens uroporphyrinogen decarb... 198 3e-50
AF104438-1|AAD04588.1| 367|Homo sapiens uroporphyrinogen decarb... 198 3e-50
AF104437-1|AAD04587.1| 367|Homo sapiens uroporphyrinogen decarb... 198 3e-50
AF104436-1|AAD04586.1| 367|Homo sapiens uroporphyrinogen decarb... 198 3e-50
AF104435-1|AAD04585.1| 367|Homo sapiens uroporphyrinogen decarb... 198 3e-50
AF104434-1|AAD04584.1| 367|Homo sapiens uroporphyrinogen decarb... 198 3e-50
AF104433-1|AAD04583.1| 367|Homo sapiens uroporphyrinogen decarb... 198 3e-50
AF104432-1|AAD04582.1| 367|Homo sapiens uroporphyrinogen decarb... 198 3e-50
AF104431-1|AAD04581.1| 367|Homo sapiens uroporphyrinogen decarb... 198 3e-50
AF104430-1|AAD04580.1| 367|Homo sapiens uroporphyrinogen decarb... 198 3e-50
AF104429-1|AAD04579.1| 367|Homo sapiens uroporphyrinogen decarb... 198 3e-50
AF104428-1|AAD04578.1| 367|Homo sapiens uroporphyrinogen decarb... 198 3e-50
AF104427-1|AAD04577.1| 367|Homo sapiens uroporphyrinogen decarb... 198 3e-50
AF104426-1|AAD04576.1| 367|Homo sapiens uroporphyrinogen decarb... 198 3e-50
AF104425-1|AAD04575.1| 367|Homo sapiens uroporphyrinogen decarb... 198 3e-50
AF104424-1|AAD04574.1| 367|Homo sapiens uroporphyrinogen decarb... 198 3e-50
AF104423-1|AAD04573.1| 367|Homo sapiens uroporphyrinogen decarb... 198 3e-50
AF104422-1|AAD04572.1| 367|Homo sapiens uroporphyrinogen decarb... 198 3e-50
AF104421-1|AAD04571.1| 367|Homo sapiens uroporphyrinogen decarb... 198 3e-50
M14016-1|AAA61258.1| 367|Homo sapiens UROD protein. 197 5e-50
AL359473-3|CAI16439.1| 193|Homo sapiens uroporphyrinogen decarb... 146 1e-34
AF103017-1|AAD04168.1| 109|Homo sapiens uroporphyrinogen decarb... 113 6e-25
M60891-1|AAB59456.1| 161|Homo sapiens uroporphyrinogen decarbox... 71 7e-12
AF103016-1|AAD04167.1| 100|Homo sapiens uroporphyrinogen decarb... 58 4e-08
BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta... 31 6.8
BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta... 31 6.8
AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein. 31 6.8
AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain deh... 31 6.8
BC131726-1|AAI31727.1| 391|Homo sapiens FAM46C protein protein. 30 9.0
BC036516-1|AAH36516.3| 391|Homo sapiens family with sequence si... 30 9.0
AL365331-1|CAH73761.1| 391|Homo sapiens family with sequence si... 30 9.0
AK000209-1|BAA91010.1| 391|Homo sapiens protein ( Homo sapiens ... 30 9.0
>AL359473-5|CAI16441.1| 227|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 227
Score = 270 bits (663), Expect = 3e-72
Identities = 133/233 (57%), Positives = 165/233 (70%), Gaps = 8/233 (3%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 2 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 61
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 62 TLQPLRRFP-LDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 120
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIP 184
S L YV +AITLTR ++ G+VPLIGF GAP LQ+FES A HL + F +F++P
Sbjct: 121 ASELGYVFQAITLTRQRLAGRVPLIGFAGAPA------LQLFESHAGHLGPQLFNKFALP 174
Query: 185 YLKDIRSGVRAKLTEKSLEQVPMTIFAKGAGHSLDIQAQLGYETIGLDWTVDP 237
Y++D+ V+A+L E L VPM IFAK +L+ AQ GYE +GLDWTV P
Sbjct: 175 YIRDVAKQVKARLREAGLAPVPMIIFAKDGHFALEELAQAGYEVVGLDWTVAP 227
>CR542057-1|CAG46854.1| 367|Homo sapiens UROD protein.
Length = 367
Score = 198 bits (484), Expect = 2e-50
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRFP-LDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 167 bits (406), Expect = 4e-41
Identities = 79/161 (49%), Positives = 106/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>CR456976-1|CAG33257.1| 367|Homo sapiens UROD protein.
Length = 367
Score = 198 bits (484), Expect = 2e-50
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRFP-LDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 167 bits (406), Expect = 4e-41
Identities = 79/161 (49%), Positives = 106/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>BT006737-1|AAP35383.1| 367|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 367
Score = 198 bits (484), Expect = 2e-50
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRFP-LDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 163 bits (397), Expect = 5e-40
Identities = 78/161 (48%), Positives = 105/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQ NLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQVNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>BC001778-1|AAH01778.1| 367|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 367
Score = 198 bits (484), Expect = 2e-50
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRFP-LDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 163 bits (397), Expect = 5e-40
Identities = 78/161 (48%), Positives = 105/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQ NLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQVNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>AL359473-4|CAI16440.1| 367|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 367
Score = 198 bits (484), Expect = 2e-50
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRFP-LDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 167 bits (406), Expect = 4e-41
Identities = 79/161 (49%), Positives = 106/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>AF047383-1|AAC03563.1| 367|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 367
Score = 198 bits (484), Expect = 2e-50
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRFP-LDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 167 bits (406), Expect = 4e-41
Identities = 79/161 (49%), Positives = 106/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>X89267-1|CAA61540.1| 367|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 367
Score = 198 bits (482), Expect = 3e-50
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRF-LLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 167 bits (406), Expect = 4e-41
Identities = 79/161 (49%), Positives = 106/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>U30787-1|AAC50482.1| 367|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 367
Score = 198 bits (482), Expect = 3e-50
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRF-LLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 167 bits (406), Expect = 4e-41
Identities = 79/161 (49%), Positives = 106/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>AY292986-1|AAP44118.1| 367|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 367
Score = 198 bits (482), Expect = 3e-50
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRF-LLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 167 bits (406), Expect = 4e-41
Identities = 79/161 (49%), Positives = 106/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>AF104440-1|AAD04590.1| 367|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 367
Score = 198 bits (482), Expect = 3e-50
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRF-LLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 167 bits (406), Expect = 4e-41
Identities = 79/161 (49%), Positives = 106/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>AF104439-1|AAD04589.1| 367|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 367
Score = 198 bits (482), Expect = 3e-50
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRF-LLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 167 bits (406), Expect = 4e-41
Identities = 79/161 (49%), Positives = 106/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>AF104438-1|AAD04588.1| 367|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 367
Score = 198 bits (482), Expect = 3e-50
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRF-LLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 167 bits (406), Expect = 4e-41
Identities = 79/161 (49%), Positives = 106/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>AF104437-1|AAD04587.1| 367|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 367
Score = 198 bits (482), Expect = 3e-50
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRF-LLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 167 bits (406), Expect = 4e-41
Identities = 79/161 (49%), Positives = 106/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>AF104436-1|AAD04586.1| 367|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 367
Score = 198 bits (482), Expect = 3e-50
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRF-LLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 167 bits (406), Expect = 4e-41
Identities = 79/161 (49%), Positives = 106/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>AF104435-1|AAD04585.1| 367|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 367
Score = 198 bits (482), Expect = 3e-50
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRF-LLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 167 bits (406), Expect = 4e-41
Identities = 79/161 (49%), Positives = 106/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>AF104434-1|AAD04584.1| 367|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 367
Score = 198 bits (482), Expect = 3e-50
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRF-LLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 167 bits (406), Expect = 4e-41
Identities = 79/161 (49%), Positives = 106/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>AF104433-1|AAD04583.1| 367|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 367
Score = 198 bits (482), Expect = 3e-50
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRF-LLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 167 bits (406), Expect = 4e-41
Identities = 79/161 (49%), Positives = 106/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>AF104432-1|AAD04582.1| 367|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 367
Score = 198 bits (482), Expect = 3e-50
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRF-LLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 167 bits (406), Expect = 4e-41
Identities = 79/161 (49%), Positives = 106/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>AF104431-1|AAD04581.1| 367|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 367
Score = 198 bits (482), Expect = 3e-50
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRF-LLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 167 bits (406), Expect = 4e-41
Identities = 79/161 (49%), Positives = 106/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>AF104430-1|AAD04580.1| 367|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 367
Score = 198 bits (482), Expect = 3e-50
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRF-LLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 167 bits (406), Expect = 4e-41
Identities = 79/161 (49%), Positives = 106/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>AF104429-1|AAD04579.1| 367|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 367
Score = 198 bits (482), Expect = 3e-50
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRF-LLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 167 bits (406), Expect = 4e-41
Identities = 79/161 (49%), Positives = 106/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>AF104428-1|AAD04578.1| 367|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 367
Score = 198 bits (482), Expect = 3e-50
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRF-LLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 167 bits (406), Expect = 4e-41
Identities = 79/161 (49%), Positives = 106/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>AF104427-1|AAD04577.1| 367|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 367
Score = 198 bits (482), Expect = 3e-50
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRF-LLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 167 bits (406), Expect = 4e-41
Identities = 79/161 (49%), Positives = 106/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>AF104426-1|AAD04576.1| 367|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 367
Score = 198 bits (482), Expect = 3e-50
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRF-LLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 167 bits (406), Expect = 4e-41
Identities = 79/161 (49%), Positives = 106/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>AF104425-1|AAD04575.1| 367|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 367
Score = 198 bits (482), Expect = 3e-50
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRF-LLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 167 bits (406), Expect = 4e-41
Identities = 79/161 (49%), Positives = 106/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>AF104424-1|AAD04574.1| 367|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 367
Score = 198 bits (482), Expect = 3e-50
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRF-LLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 167 bits (406), Expect = 4e-41
Identities = 79/161 (49%), Positives = 106/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>AF104423-1|AAD04573.1| 367|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 367
Score = 198 bits (482), Expect = 3e-50
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRF-LLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 167 bits (406), Expect = 4e-41
Identities = 79/161 (49%), Positives = 106/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>AF104422-1|AAD04572.1| 367|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 367
Score = 198 bits (482), Expect = 3e-50
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRF-LLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 167 bits (406), Expect = 4e-41
Identities = 79/161 (49%), Positives = 106/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>AF104421-1|AAD04571.1| 367|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 367
Score = 198 bits (482), Expect = 3e-50
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRF-LLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 167 bits (406), Expect = 4e-41
Identities = 79/161 (49%), Positives = 106/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>M14016-1|AAA61258.1| 367|Homo sapiens UROD protein.
Length = 367
Score = 197 bits (480), Expect = 5e-50
Identities = 94/151 (62%), Positives = 113/151 (74%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M P GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRFP-LDAAIIFSDILVVPQALGMEVTMVPSKGPSFPEPLREEQDLEALRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 167 bits (406), Expect = 4e-41
Identities = 79/161 (49%), Positives = 106/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>AL359473-3|CAI16439.1| 193|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 193
Score = 146 bits (353), Expect = 1e-34
Identities = 78/151 (51%), Positives = 94/151 (62%), Gaps = 23/151 (15%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TL QALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TL----------------------QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 106
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 107 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 137
>AF103017-1|AAD04168.1| 109|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 109
Score = 113 bits (273), Expect = 6e-25
Identities = 53/100 (53%), Positives = 67/100 (67%)
Query: 209 IFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIKT 268
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 2 IFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIGQ 61
Query: 269 LTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 62 LVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 101
>M60891-1|AAB59456.1| 161|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 161
Score = 70.5 bits (165), Expect = 7e-12
Identities = 34/64 (53%), Positives = 44/64 (68%), Gaps = 1/64 (1%)
Query: 93 GMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGAVSRLDYVGKAITLTRHKIDGKVPLIGF 151
GM V M P GP FP+PL+ +++ L+ PE S L YV +AITLTR ++ G+VPLIGF
Sbjct: 1 GMEVTMVPSKGPSFPEPLREEQDLEALRDPEVVASELGYVFQAITLTRQRLAGRVPLIGF 60
Query: 152 TGAP 155
GAP
Sbjct: 61 AGAP 64
Score = 50.0 bits (114), Expect = 1e-05
Identities = 25/60 (41%), Positives = 37/60 (61%), Gaps = 3/60 (5%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQL FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 105 LVPYLVGQVVAGAQL---FESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 161
>AF103016-1|AAD04167.1| 100|Homo sapiens uroporphyrinogen
decarboxylase protein.
Length = 100
Score = 58.0 bits (134), Expect = 4e-08
Identities = 26/60 (43%), Positives = 39/60 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 41 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 100
>BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 30.7 bits (66), Expect = 6.8
Identities = 13/36 (36%), Positives = 23/36 (63%), Gaps = 1/36 (2%)
Query: 264 EEIKTLTTEMVKKFGK-HRYIANLGHGITPQTPLES 298
+++KTL +E +++FG+ + N GH PQ P E+
Sbjct: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEET 102
>BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 30.7 bits (66), Expect = 6.8
Identities = 13/36 (36%), Positives = 23/36 (63%), Gaps = 1/36 (2%)
Query: 264 EEIKTLTTEMVKKFGK-HRYIANLGHGITPQTPLES 298
+++KTL +E +++FG+ + N GH PQ P E+
Sbjct: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEET 102
>AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein.
Length = 270
Score = 30.7 bits (66), Expect = 6.8
Identities = 13/36 (36%), Positives = 23/36 (63%), Gaps = 1/36 (2%)
Query: 264 EEIKTLTTEMVKKFGK-HRYIANLGHGITPQTPLES 298
+++KTL +E +++FG+ + N GH PQ P E+
Sbjct: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEET 102
>AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR3 protein.
Length = 270
Score = 30.7 bits (66), Expect = 6.8
Identities = 13/36 (36%), Positives = 23/36 (63%), Gaps = 1/36 (2%)
Query: 264 EEIKTLTTEMVKKFGK-HRYIANLGHGITPQTPLES 298
+++KTL +E +++FG+ + N GH PQ P E+
Sbjct: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEET 102
>BC131726-1|AAI31727.1| 391|Homo sapiens FAM46C protein protein.
Length = 391
Score = 30.3 bits (65), Expect = 9.0
Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 3/97 (3%)
Query: 186 LKDIRSGVRAKLTEKSLEQVPMTIFAKGAGHSLDIQAQLGYETIGLDWTVD-PTEARKIV 244
LKDI VR++L E ++ + + AGH L LG + + L + V PTEA +
Sbjct: 48 LKDIVQTVRSRLEEAGIKVHDVRLNGSAAGHVLVKDNGLGCKDLDLIFHVALPTEAEFQL 107
Query: 245 GENITLQG--NLDPQDLYKTPEEIKTLTTEMVKKFGK 279
++ L N P+ + K TL V+K K
Sbjct: 108 VRDVVLCSLLNFLPEGVNKLKISPVTLKEAYVQKLVK 144
>BC036516-1|AAH36516.3| 391|Homo sapiens family with sequence
similarity 46, member C protein.
Length = 391
Score = 30.3 bits (65), Expect = 9.0
Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 3/97 (3%)
Query: 186 LKDIRSGVRAKLTEKSLEQVPMTIFAKGAGHSLDIQAQLGYETIGLDWTVD-PTEARKIV 244
LKDI VR++L E ++ + + AGH L LG + + L + V PTEA +
Sbjct: 48 LKDIVQTVRSRLEEAGIKVHDVRLNGSAAGHVLVKDNGLGCKDLDLIFHVALPTEAEFQL 107
Query: 245 GENITLQG--NLDPQDLYKTPEEIKTLTTEMVKKFGK 279
++ L N P+ + K TL V+K K
Sbjct: 108 VRDVVLCSLLNFLPEGVNKLKISPVTLKEAYVQKLVK 144
>AL365331-1|CAH73761.1| 391|Homo sapiens family with sequence
similarity 46, member C protein.
Length = 391
Score = 30.3 bits (65), Expect = 9.0
Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 3/97 (3%)
Query: 186 LKDIRSGVRAKLTEKSLEQVPMTIFAKGAGHSLDIQAQLGYETIGLDWTVD-PTEARKIV 244
LKDI VR++L E ++ + + AGH L LG + + L + V PTEA +
Sbjct: 48 LKDIVQTVRSRLEEAGIKVHDVRLNGSAAGHVLVKDNGLGCKDLDLIFHVALPTEAEFQL 107
Query: 245 GENITLQG--NLDPQDLYKTPEEIKTLTTEMVKKFGK 279
++ L N P+ + K TL V+K K
Sbjct: 108 VRDVVLCSLLNFLPEGVNKLKISPVTLKEAYVQKLVK 144
>AK000209-1|BAA91010.1| 391|Homo sapiens protein ( Homo sapiens
cDNA FLJ20202 fis, clone COLF1326. ).
Length = 391
Score = 30.3 bits (65), Expect = 9.0
Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 3/97 (3%)
Query: 186 LKDIRSGVRAKLTEKSLEQVPMTIFAKGAGHSLDIQAQLGYETIGLDWTVD-PTEARKIV 244
LKDI VR++L E ++ + + AGH L LG + + L + V PTEA +
Sbjct: 48 LKDIVQTVRSRLEEAGIKVHDVRLNGSAAGHVLVKDNGLGCKDLDLIFHVALPTEAEFQL 107
Query: 245 GENITLQG--NLDPQDLYKTPEEIKTLTTEMVKKFGK 279
++ L N P+ + K TL V+K K
Sbjct: 108 VRDVVLCSLLNFLPEGVNKLKISPVTLKEAYVQKLVK 144
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.318 0.136 0.398
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 46,836,805
Number of Sequences: 224733
Number of extensions: 2008458
Number of successful extensions: 4140
Number of sequences better than 10.0: 43
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 4008
Number of HSP's gapped (non-prelim): 75
length of query: 310
length of database: 73,234,838
effective HSP length: 90
effective length of query: 220
effective length of database: 53,008,868
effective search space: 11661950960
effective search space used: 11661950960
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 65 (30.3 bits)
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