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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000936-TA|BGIBMGA000936-PA|IPR004788|Ribose 5-phosphate
isomerase
         (237 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q5TQ02 Cluster: ENSANGP00000028512; n=4; Coelomata|Rep:...   353   2e-96
UniRef50_UPI00015B4259 Cluster: PREDICTED: similar to ribose-5-p...   336   3e-91
UniRef50_Q8MLS2 Cluster: CG30410-PA; n=1; Drosophila melanogaste...   310   3e-83
UniRef50_P49247 Cluster: Ribose-5-phosphate isomerase; n=29; Euk...   295   8e-79
UniRef50_Q5DFM4 Cluster: SJCHGC03376 protein; n=1; Schistosoma j...   268   1e-70
UniRef50_P41994 Cluster: Probable-ribose 5-phosphate isomerase; ...   230   3e-59
UniRef50_Q9UTL3 Cluster: Ribose 5-phosphate isomerase; n=7; Dika...   219   5e-56
UniRef50_Q12189 Cluster: Ribose-5-phosphate isomerase; n=8; Sacc...   219   5e-56
UniRef50_Q8Q0R3 Cluster: Ribose-5-phosphate isomerase A; n=7; Ar...   176   5e-43
UniRef50_Q81PL1 Cluster: Ribose-5-phosphate isomerase A; n=11; F...   160   2e-38
UniRef50_Q9V0L6 Cluster: Ribose-5-phosphate isomerase A; n=4; Th...   158   1e-37
UniRef50_A3H6Q6 Cluster: Ribose 5-phosphate isomerase; n=1; Cald...   153   5e-36
UniRef50_Q2FLE9 Cluster: Ribose 5-phosphate isomerase; n=2; Meth...   151   1e-35
UniRef50_Q7U8K8 Cluster: Ribose-5-phosphate isomerase A; n=39; c...   151   1e-35
UniRef50_Q6LY04 Cluster: Ribose-5-phosphate isomerase A; n=6; Eu...   150   3e-35
UniRef50_Q2CFA5 Cluster: Ribose 5-phosphate isomerase; n=2; Alph...   150   3e-35
UniRef50_Q5UZD7 Cluster: Ribose-5-phosphate isomerase A; n=2; ce...   147   2e-34
UniRef50_Q7R8N6 Cluster: Ribose 5-phosphate isomerase; n=6; Plas...   146   3e-34
UniRef50_Q5G570 Cluster: Ribose 5-phosphate isomerase-like prote...   146   4e-34
UniRef50_A6LDT5 Cluster: Putative ribose 5-phosphate isomerase; ...   145   7e-34
UniRef50_O83625 Cluster: Ribose-5-phosphate isomerase A; n=2; Tr...   143   3e-33
UniRef50_O29319 Cluster: Ribose-5-phosphate isomerase A; n=1; Ar...   142   5e-33
UniRef50_Q2JK16 Cluster: Ribose 5-phosphate isomerase A; n=7; ce...   142   7e-33
UniRef50_Q5LTT5 Cluster: Ribose-5-phosphate isomerase A; n=28; A...   141   1e-32
UniRef50_A7I6S5 Cluster: Ribose 5-phosphate isomerase; n=1; Cand...   140   3e-32
UniRef50_Q8EMZ1 Cluster: Ribose-5-phosphate isomerase A 2; n=1; ...   139   5e-32
UniRef50_A7P3I3 Cluster: Chromosome chr1 scaffold_5, whole genom...   138   1e-31
UniRef50_Q5FQ98 Cluster: Ribose-5-phosphate isomerase A; n=4; Ba...   136   5e-31
UniRef50_UPI0000E87CBD Cluster: ribose-5-phosphate isomerase A; ...   135   8e-31
UniRef50_Q5WCM4 Cluster: Ribose-5-phosphate isomerase A; n=1; Ba...   134   2e-30
UniRef50_Q1GX07 Cluster: Ribose 5-phosphate isomerase; n=1; Sphi...   132   6e-30
UniRef50_A7AMM8 Cluster: Ribose 5-phosphate isomerase A family p...   132   6e-30
UniRef50_A3XMJ2 Cluster: Ribose 5-phosphate isomerase; n=1; Leeu...   131   1e-29
UniRef50_Q9HN33 Cluster: Ribose-5-phosphate isomerase A; n=3; Ha...   131   2e-29
UniRef50_Q9RW24 Cluster: Ribose-5-phosphate isomerase A; n=4; De...   131   2e-29
UniRef50_Q6N8C3 Cluster: Ribose-5-phosphate isomerase A; n=6; Al...   129   5e-29
UniRef50_Q0SCN2 Cluster: Ribose-5-phosphate isomerase; n=1; Rhod...   129   7e-29
UniRef50_A7D0F8 Cluster: Ribose 5-phosphate isomerase; n=1; Halo...   128   9e-29
UniRef50_Q6MC00 Cluster: Ribose-5-phosphate isomerase A; n=1; Ca...   128   9e-29
UniRef50_A1CTV2 Cluster: Ribose 5-phosphate isomerase A; n=4; Eu...   128   1e-28
UniRef50_Q8ZGJ9 Cluster: Ribose-5-phosphate isomerase A 2; n=9; ...   127   2e-28
UniRef50_Q8A699 Cluster: Putative ribose 5-phosphate isomerase; ...   127   3e-28
UniRef50_O51601 Cluster: Ribose-5-phosphate isomerase A; n=3; Bo...   127   3e-28
UniRef50_A3DN78 Cluster: Ribose 5-phosphate isomerase; n=1; Stap...   126   4e-28
UniRef50_Q9HJT5 Cluster: Ribose-5-phosphate isomerase A; n=2; Th...   126   4e-28
UniRef50_Q139E9 Cluster: Ribose 5-phosphate isomerase; n=2; Alph...   126   5e-28
UniRef50_Q1ERB6 Cluster: Ribose 5-phosphate isomerase; n=1; uncu...   126   5e-28
UniRef50_Q6L1K2 Cluster: Ribose-5-phosphate isomerase A; n=2; Th...   125   9e-28
UniRef50_Q0UHN5 Cluster: Putative uncharacterized protein; n=3; ...   125   1e-27
UniRef50_A5ABI2 Cluster: Catalytic activity: RPIs catalyse the r...   124   1e-27
UniRef50_A1RX06 Cluster: Ribose 5-phosphate isomerase; n=1; Ther...   124   2e-27
UniRef50_Q1H2B3 Cluster: Ribose 5-phosphate isomerase; n=1; Meth...   124   3e-27
UniRef50_Q11IC0 Cluster: Ribose 5-phosphate isomerase; n=4; Bact...   124   3e-27
UniRef50_Q8YH30 Cluster: Ribose-5-phosphate isomerase A; n=32; B...   122   6e-27
UniRef50_Q01M03 Cluster: OSIGBa0096F13.7 protein; n=4; Oryza sat...   122   8e-27
UniRef50_Q8G3X9 Cluster: Ribose-5-phosphate isomerase A; n=14; B...   122   1e-26
UniRef50_A6LVZ7 Cluster: Ribose 5-phosphate isomerase; n=1; Clos...   121   1e-26
UniRef50_Q5HLQ9 Cluster: Ribose-5-phosphate isomerase A; n=16; S...   121   2e-26
UniRef50_P0A7Z3 Cluster: Ribose-5-phosphate isomerase A; n=115; ...   120   4e-26
UniRef50_P57961 Cluster: Ribose-5-phosphate isomerase A; n=28; P...   120   4e-26
UniRef50_Q92D46 Cluster: Ribose-5-phosphate isomerase A; n=13; L...   118   1e-25
UniRef50_Q8ZXY8 Cluster: Ribose 5-phosphate isomerase; n=5; Ther...   116   4e-25
UniRef50_Q4MZ63 Cluster: Ribose 5-phosphate epimerase, putative;...   116   5e-25
UniRef50_A0RTM4 Cluster: Ribose 5-phosphate isomerase; n=2; Ther...   116   5e-25
UniRef50_Q97J55 Cluster: Ribose 5-phosphate isomerase; n=2; Clos...   115   9e-25
UniRef50_A6RS68 Cluster: Putative uncharacterized protein; n=2; ...   110   3e-23
UniRef50_UPI00015BAFE1 Cluster: ribose 5-phosphate isomerase; n=...   109   5e-23
UniRef50_Q03Y20 Cluster: Ribose 5-phosphate isomerase; n=1; Leuc...   109   5e-23
UniRef50_A5EVM0 Cluster: Ribose 5-phosphate isomerase; n=1; Dich...   109   8e-23
UniRef50_A5FY01 Cluster: Ribose 5-phosphate isomerase; n=1; Acid...   108   1e-22
UniRef50_O84215 Cluster: Ribose-5-phosphate isomerase A; n=7; Ch...   106   6e-22
UniRef50_Q4J990 Cluster: Ribose 5-phosphate isomerase; n=2; Sulf...   105   7e-22
UniRef50_Q62K38 Cluster: Ribose-5-phosphate isomerase A; n=132; ...   105   1e-21
UniRef50_Q8E4Y6 Cluster: Ribose-5-phosphate isomerase A; n=22; c...   104   2e-21
UniRef50_Q97ZD9 Cluster: Ribose 5-phosphate isomerase; n=2; Sulf...   102   9e-21
UniRef50_Q97RI7 Cluster: Ribose-5-phosphate isomerase A; n=28; L...   102   9e-21
UniRef50_Q88YY5 Cluster: Ribose-5-phosphate isomerase A; n=3; La...   102   9e-21
UniRef50_Q74KF3 Cluster: Ribose-5-phosphate isomerase A; n=3; La...   101   2e-20
UniRef50_Q5F831 Cluster: Ribose-5-phosphate isomerase A; n=5; Be...   100   3e-20
UniRef50_Q8P1C5 Cluster: Ribose-5-phosphate isomerase A; n=15; L...    99   5e-20
UniRef50_A6E944 Cluster: Ribose 5-phosphate isomerase; n=1; Pedo...    99   8e-20
UniRef50_Q4FT49 Cluster: Ribose 5-phosphate isomerase; n=5; Gamm...    97   3e-19
UniRef50_A3XYG4 Cluster: Ribose 5-phosphate isomerase; n=2; Vibr...    92   1e-17
UniRef50_A5BTA5 Cluster: Putative uncharacterized protein; n=1; ...    92   1e-17
UniRef50_Q9YEA9 Cluster: Ribose-5-phosphate isomerase A; n=1; Ae...    91   3e-17
UniRef50_Q8TUT8 Cluster: Ribose 5-phosphate isomerase; n=1; Meth...    90   5e-17
UniRef50_Q41DL3 Cluster: Ribose 5-phosphate isomerase; n=1; Exig...    88   2e-16
UniRef50_Q8SR79 Cluster: RIBOSE 5-PHOSPHATE ISOMERASE; n=1; Ence...    86   6e-16
UniRef50_Q88ZG6 Cluster: Ribose 5-phosphate epimerase; n=1; Lact...    85   1e-15
UniRef50_A2BLS3 Cluster: Ribose-5-phosphate isomerase A; n=1; Hy...    81   2e-14
UniRef50_Q9FI13 Cluster: Similarity to ribose 5-phosphate isomer...    77   4e-13
UniRef50_Q10CS9 Cluster: Ribose 5-phosphate isomerase, putative,...    65   1e-09
UniRef50_Q1WS86 Cluster: Ribose 5-phosphate isomerase; n=1; Lact...    62   2e-08
UniRef50_Q035R3 Cluster: Ribose 5-phosphate isomerase; n=1; Lact...    62   2e-08
UniRef50_Q5FJW2 Cluster: Ribose 5-phosphate; n=1; Lactobacillus ...    49   9e-05
UniRef50_O67166 Cluster: Gamma-glutamyl phosphate reductase; n=1...    41   0.031
UniRef50_A5V6Z7 Cluster: Sensor protein; n=1; Sphingomonas witti...    37   0.39 
UniRef50_P19320 Cluster: Vascular cell adhesion protein 1 precur...    37   0.51 
UniRef50_Q6C6M6 Cluster: Similar to CA0775|CaIFK2 Candida albica...    36   1.2  
UniRef50_Q22B19 Cluster: Putative uncharacterized protein; n=1; ...    35   2.1  
UniRef50_A2Q8F6 Cluster: Putative uncharacterized protein; n=1; ...    34   2.7  
UniRef50_UPI0000F1E6F4 Cluster: PREDICTED: similar to regulatory...    33   4.8  
UniRef50_A6PGC1 Cluster: Sensor protein; n=1; Shewanella sedimin...    33   4.8  
UniRef50_Q6FTF7 Cluster: Similar to tr|Q08926 Saccharomyces cere...    33   4.8  
UniRef50_O28109 Cluster: 2-nitropropane dioxygenase; n=1; Archae...    33   4.8  
UniRef50_Q55CU4 Cluster: Putative uncharacterized protein; n=1; ...    33   6.3  
UniRef50_Q3JDC9 Cluster: Putative uncharacterized protein; n=3; ...    33   8.3  

>UniRef50_Q5TQ02 Cluster: ENSANGP00000028512; n=4; Coelomata|Rep:
           ENSANGP00000028512 - Anopheles gambiae str. PEST
          Length = 235

 Score =  353 bits (869), Expect = 2e-96
 Identities = 165/234 (70%), Positives = 198/234 (84%), Gaps = 1/234 (0%)

Query: 1   MSLEQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQA 60
           MSLE+AK+ AAY+AVD++V +N + GVGSGSTVVYAV R+AERV++E LK+ CIPTSFQA
Sbjct: 1   MSLEEAKKCAAYKAVDEYVKDNTVVGVGSGSTVVYAVHRIAERVKAEGLKLVCIPTSFQA 60

Query: 61  KQLIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVI 120
           +QLII+HGL LG+LE NP +D  IDGADEVD+ M LIKGGGGCLLQEKI+ASC+ +L+VI
Sbjct: 61  RQLIIEHGLVLGDLECNPRLDCAIDGADEVDAKMVLIKGGGGCLLQEKIVASCADRLVVI 120

Query: 121 ADYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGN 180
           ADYTKDS KLG +Y+KG+PIEV PMAYVPIK K+ S +GG +KLR AVAKAGPVVTDNGN
Sbjct: 121 ADYTKDSAKLGQQYRKGIPIEVAPMAYVPIKGKVESRFGGTLKLRMAVAKAGPVVTDNGN 180

Query: 181 FILDWMF-ANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGNVVERS 233
           FILDW F A++  DW+ VN  I +IPGVV+TGLFV M  KAYFGQ +G+V ERS
Sbjct: 181 FILDWSFPADKEHDWDAVNREIMMIPGVVDTGLFVGMATKAYFGQQDGSVTERS 234


>UniRef50_UPI00015B4259 Cluster: PREDICTED: similar to
           ribose-5-phosphate isomerase; n=1; Nasonia
           vitripennis|Rep: PREDICTED: similar to
           ribose-5-phosphate isomerase - Nasonia vitripennis
          Length = 347

 Score =  336 bits (826), Expect = 3e-91
 Identities = 150/231 (64%), Positives = 192/231 (83%)

Query: 2   SLEQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAK 61
           +LE AK++AAY+AVD++V +N + G+GSGST+VYAVQRLAERV+ EKL V C+PTSFQA+
Sbjct: 5   TLESAKKIAAYKAVDEYVKDNSVIGIGSGSTIVYAVQRLAERVKEEKLNVVCVPTSFQAR 64

Query: 62  QLIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIA 121
           QLII + L+LG+LET+P +D  IDGADEVD ++ LIKGGGGCLLQEKI+ASC+  L++IA
Sbjct: 65  QLIINNHLSLGDLETHPQLDFAIDGADEVDCDLNLIKGGGGCLLQEKIVASCTDTLVIIA 124

Query: 122 DYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNF 181
           DYTK+S KLG++YKKG+P+EV+PMAYVPI+ K+   +GG +KLR AVAKAGPVVTDNGNF
Sbjct: 125 DYTKNSQKLGEQYKKGLPLEVVPMAYVPIRRKVEEDFGGSVKLRMAVAKAGPVVTDNGNF 184

Query: 182 ILDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGNVVER 232
           ILDW F +   DW  VN  +  IPG+VETGLFVNM  K +FG P+G++ E+
Sbjct: 185 ILDWQFPDNVKDWPAVNQKLLSIPGLVETGLFVNMAKKVFFGMPDGSIKEQ 235


>UniRef50_Q8MLS2 Cluster: CG30410-PA; n=1; Drosophila
           melanogaster|Rep: CG30410-PA - Drosophila melanogaster
           (Fruit fly)
          Length = 280

 Score =  310 bits (760), Expect = 3e-83
 Identities = 147/233 (63%), Positives = 186/233 (79%), Gaps = 4/233 (1%)

Query: 1   MSLEQAKQVAAYQAVDQFVTNNC-IFGVGSGSTVVYAVQRLAERV--ESEKLKVTCIPTS 57
           ++L+ AK+ AA  AVDQ+VT +  I G+GSGSTVVYAVQR+AERV  E E   + C+P+S
Sbjct: 43  IALDAAKKTAARTAVDQWVTEDTKILGIGSGSTVVYAVQRIAERVWKEGELTDLICVPSS 102

Query: 58  FQAKQLIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKL 117
           +QA+ LI+ + LNLG+L+ NPNIDV IDGADEVD +M LIKGGGGCLLQEK++ASC+K  
Sbjct: 103 YQARHLILDYNLNLGDLDRNPNIDVAIDGADEVDRHMVLIKGGGGCLLQEKVVASCAKHF 162

Query: 118 IVIADYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTD 177
           IV+ADYTK+S++LG+++ +GVPIEV PMAYVPIK  I +L+GGE  LR A  KAGP+VTD
Sbjct: 163 IVVADYTKNSIRLGEQWCRGVPIEVAPMAYVPIKLHIEALFGGEASLRMAKVKAGPIVTD 222

Query: 178 NGNFILDWMF-ANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGNV 229
           NGNF+LDW F AN+  DW++VN  I LIPGV+ETGLFVNM  K Y+G   G+V
Sbjct: 223 NGNFLLDWKFIANREYDWDEVNRAITLIPGVLETGLFVNMAHKCYYGMANGSV 275


>UniRef50_P49247 Cluster: Ribose-5-phosphate isomerase; n=29;
           Eukaryota|Rep: Ribose-5-phosphate isomerase - Homo
           sapiens (Human)
          Length = 311

 Score =  295 bits (723), Expect = 8e-79
 Identities = 134/226 (59%), Positives = 176/226 (77%), Gaps = 1/226 (0%)

Query: 4   EQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQL 63
           E+AK++A   AV+  V NN + G+GSGST+V+AVQR+AERV+ E L + CIPTSFQA+QL
Sbjct: 79  EEAKKLAGRAAVENHVRNNQVLGIGSGSTIVHAVQRIAERVKQENLNLVCIPTSFQARQL 138

Query: 64  IIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADY 123
           I+++GL L +L+ +P ID+ IDGADEVD+++ LIKGGGGCL QEKI+A  + + IVIAD+
Sbjct: 139 ILQYGLTLSDLDRHPEIDLAIDGADEVDADLNLIKGGGGCLTQEKIVAGYASRFIVIADF 198

Query: 124 TKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFIL 183
            KDS  LGD++ KG+PIEVIPMAYVP+   +   +GG ++LR AV KAGPVVTDNGNFIL
Sbjct: 199 RKDSKNLGDQWHKGIPIEVIPMAYVPVSRAVSQKFGGVVELRMAVNKAGPVVTDNGNFIL 258

Query: 184 DWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGNV 229
           DW F   +  W +VN  IK+IPGVV+TGLF+NM  + YFG  +G+V
Sbjct: 259 DWKFDRVH-KWSEVNTAIKMIPGVVDTGLFINMAERVYFGMQDGSV 303


>UniRef50_Q5DFM4 Cluster: SJCHGC03376 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC03376 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 259

 Score =  268 bits (656), Expect = 1e-70
 Identities = 128/229 (55%), Positives = 167/229 (72%), Gaps = 1/229 (0%)

Query: 2   SLEQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAK 61
           +LE AKQ A   AV  ++ +N I G+GSG+T+ YAV+ +AE+VESE L++ CIPTSFQA+
Sbjct: 6   ALECAKQKACQSAVSDWLKDNQIIGLGSGTTIKYAVEFIAEKVESENLQIQCIPTSFQAR 65

Query: 62  QLIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIA 121
           QL+I H L + +L+ +  IDVT DGADEVD ++ LIKGGGGCLLQEKI+ASC+   I I 
Sbjct: 66  QLLINHKLPVTDLDIHEKIDVTFDGADEVDEDLHLIKGGGGCLLQEKIVASCTANFIAIV 125

Query: 122 DYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNF 181
           D  K S +LG  + KG+PIEVIPMA+ PI+ +I  L+GG++ LR AV+K GPVVTDNGNF
Sbjct: 126 DERKHSKRLGSYWTKGLPIEVIPMAFKPIQTRIEKLFGGKVILREAVSKMGPVVTDNGNF 185

Query: 182 ILDWMF-ANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGNV 229
           +LDW F  N+   W +VN  +  IPGVV+TGLF+NM  + Y G   G V
Sbjct: 186 LLDWKFDTNKQYYWPEVNIELSNIPGVVDTGLFINMARRIYVGNMNGTV 234


>UniRef50_P41994 Cluster: Probable-ribose 5-phosphate isomerase;
           n=2; Caenorhabditis|Rep: Probable-ribose 5-phosphate
           isomerase - Caenorhabditis elegans
          Length = 251

 Score =  230 bits (562), Expect = 3e-59
 Identities = 113/232 (48%), Positives = 150/232 (64%), Gaps = 4/232 (1%)

Query: 3   LEQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLK-VTCIPTSFQAK 61
           +EQAK+ AA+   +++V + C  GVGSGSTV Y V+ L +  ++  LK + C+PTSF  K
Sbjct: 14  IEQAKKRAAFACGEKYVQSGCRLGVGSGSTVKYLVEYLKQGFQNGSLKDIICVPTSFLTK 73

Query: 62  QLIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIA 121
           Q +I+ GL + +L+++P +DV IDGADEVD   T IKGGGGCL QEKI+ + +K   VIA
Sbjct: 74  QWLIESGLPVSDLDSHPELDVCIDGADEVDGQFTCIKGGGGCLAQEKIVQTAAKNFYVIA 133

Query: 122 DYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNF 181
           DY KDS  LGDRY   VPIEV+P+A  P+   I    GG  +LR AV K GP+VTDNGNF
Sbjct: 134 DYLKDSKHLGDRY-PNVPIEVLPLAAQPLLRSIPRAEGGSCQLRQAVKKCGPIVTDNGNF 192

Query: 182 ILDWMFAN--QNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGNVVE 231
           I+DW F       DW  +   +   PG+VETGLF+      +F   +G+V E
Sbjct: 193 IIDWQFEKNVSGRDWFAIQQRLANTPGIVETGLFIGCVDAVFFAYSDGSVKE 244


>UniRef50_Q9UTL3 Cluster: Ribose 5-phosphate isomerase; n=7;
           Dikarya|Rep: Ribose 5-phosphate isomerase -
           Schizosaccharomyces pombe (Fission yeast)
          Length = 274

 Score =  219 bits (535), Expect = 5e-56
 Identities = 119/238 (50%), Positives = 163/238 (68%), Gaps = 6/238 (2%)

Query: 3   LEQAKQVAAYQAVDQ-FVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAK 61
           +E AK++A + AVD+ +  N  + G+GSGSTVVY V+RL  +   +   V  IPT FQ+K
Sbjct: 13  IELAKRLACHMAVDENYPENPKVIGIGSGSTVVYVVERLLTKPGVDS--VVFIPTGFQSK 70

Query: 62  QLIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIA 121
           QLI+ +GL LG+ +  PN+DV+ DGADEVD N+  IKGGG CL QEK+IA  +K+L+++A
Sbjct: 71  QLIVNNGLRLGDPDCYPNVDVSFDGADEVDDNLQCIKGGGACLFQEKLIAFLAKRLVIVA 130

Query: 122 DYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLR-SAVAKAGPVVTDNGN 180
           D  K+S  LG+ +KKGVPIEV+PMAY  I  +++ L   E KLR  A  KAGPVVTDNGN
Sbjct: 131 DSRKNSHVLGEYWKKGVPIEVMPMAYASILPQLVELGAIEPKLRMGAPGKAGPVVTDNGN 190

Query: 181 FILDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGNV-VERSVIEK 237
           FI+D  F     + +++   IKL+ GVVE GLF +M    YFG  +G+V V+++  EK
Sbjct: 191 FIIDAHFGLIK-NPKELFAKIKLLVGVVEVGLFCDMISAVYFGSKDGSVTVKKASGEK 247


>UniRef50_Q12189 Cluster: Ribose-5-phosphate isomerase; n=8;
           Saccharomycetales|Rep: Ribose-5-phosphate isomerase -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 258

 Score =  219 bits (535), Expect = 5e-56
 Identities = 114/237 (48%), Positives = 160/237 (67%), Gaps = 11/237 (4%)

Query: 3   LEQAKQVAAYQAVDQFVT--NNCIFGVGSGSTVVYAVQRLAERVESEKL-----KVTCIP 55
           LE AK+ AAY+AVD+ +   ++ I G+GSGSTVVY  +R+ + +   K      K  CIP
Sbjct: 18  LEDAKRAAAYRAVDENLKFDDHKIIGIGSGSTVVYVAERIGQYLHDPKFYEVASKFICIP 77

Query: 56  TSFQAKQLIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSK 115
           T FQ++ LI+ + L LG +E  P ID+  DGADEVD N+ LIKGGG CL QEK++++ +K
Sbjct: 78  TGFQSRNLILDNKLQLGSIEQYPRIDIAFDGADEVDENLQLIKGGGACLFQEKLVSTSAK 137

Query: 116 KLIVIADYTKDSVK-LGDRYKKGVPIEVIPMAYVPIKNKII-SLYGGEIKLR-SAVAKAG 172
             IV+AD  K S K LG  +++GVPIE++P +YV +KN ++  L+  ++ +R    AKAG
Sbjct: 138 TFIVVADSRKKSPKHLGKNWRQGVPIEIVPSSYVRVKNDLLEQLHAEKVDIRQGGSAKAG 197

Query: 173 PVVTDNGNFILDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGNV 229
           PVVTDN NFI+D  F   + D  K++  IKL+ GVVETGLF++   KAYFG  +G+V
Sbjct: 198 PVVTDNNNFIIDADFGEIS-DPRKLHREIKLLVGVVETGLFIDNASKAYFGNSDGSV 253


>UniRef50_Q8Q0R3 Cluster: Ribose-5-phosphate isomerase A; n=7;
           Archaea|Rep: Ribose-5-phosphate isomerase A -
           Methanosarcina mazei (Methanosarcina frisia)
          Length = 234

 Score =  176 bits (428), Expect = 5e-43
 Identities = 96/228 (42%), Positives = 143/228 (62%), Gaps = 7/228 (3%)

Query: 2   SLEQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAK 61
           S +  ++ AA  A    V++  + G+G+GSTV Y ++ L  RV+ E L +  + TS+Q++
Sbjct: 7   STDSPEKRAAGIAAAGLVSSGMVVGLGTGSTVAYTIKELGRRVKEEGLDILGVVTSYQSE 66

Query: 62  QLIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIA 121
            L I  G+ L  L  +P +D+ IDGAD++DSN+  IKGGG    +EKI++  +K+ +V+A
Sbjct: 67  MLAIDAGIRLTTLSQDPELDIAIDGADQIDSNLYTIKGGGAAHTREKIVSVSAKRFVVVA 126

Query: 122 DYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNF 181
           D +K S +L     K VP+EV+P A  P  N+I  L GGE +LRSAV K GPV+TDNGNF
Sbjct: 127 DDSKTSTQL----DKPVPVEVLPFAKEPAVNRIRKL-GGEPRLRSAVKKDGPVITDNGNF 181

Query: 182 ILDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGNV 229
           +LD  F     D E +   +  +PGVVE G+F N+  + Y G+ +G+V
Sbjct: 182 VLDVEFGVIK-DPEALALQLSAVPGVVEHGIFSNV-DELYIGKKDGSV 227


>UniRef50_Q81PL1 Cluster: Ribose-5-phosphate isomerase A; n=11;
           Firmicutes|Rep: Ribose-5-phosphate isomerase A -
           Bacillus anthracis
          Length = 220

 Score =  160 bits (389), Expect = 2e-38
 Identities = 95/221 (42%), Positives = 135/221 (61%), Gaps = 8/221 (3%)

Query: 7   KQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIK 66
           KQ+A   A   FV +    G+G+GST  + +Q+L +RV+ E L +  +PTS + + L  +
Sbjct: 4   KQIAGEYAAT-FVKDGMKIGLGTGSTAYWTIQKLGQRVK-EGLSIQAVPTSKETEALAQQ 61

Query: 67  HGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTKD 126
             + L  L    ++D+TIDGADE+DSN+ LIKGGGG LL+EKI+AS SK+LI+I D +K 
Sbjct: 62  LNIPLISLNDVQSLDLTIDGADEIDSNLQLIKGGGGALLREKIVASSSKELIIIVDESKV 121

Query: 127 SVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFILDWM 186
             +LG      +PIE+IP A+   ++KI SL G +  LR  +      +TDN N I+D +
Sbjct: 122 VTRLG---TFPLPIEIIPFAWKQTESKIQSL-GCQTTLR--LKNNETFITDNNNMIIDCI 175

Query: 187 FANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEG 227
           F N       ++  +K+I GVVETGLFVNM  KA  G   G
Sbjct: 176 FPNHIPTPSDLHKRLKMITGVVETGLFVNMTSKAIIGTKNG 216


>UniRef50_Q9V0L6 Cluster: Ribose-5-phosphate isomerase A; n=4;
           Thermococcaceae|Rep: Ribose-5-phosphate isomerase A -
           Pyrococcus abyssi
          Length = 229

 Score =  158 bits (383), Expect = 1e-37
 Identities = 94/230 (40%), Positives = 139/230 (60%), Gaps = 10/230 (4%)

Query: 1   MSLEQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLK-VTCIPTSFQ 59
           M++E+ K++AA +A+ +F+ ++ + G+G+GST  Y ++ L + ++  ++  +  +PTS+Q
Sbjct: 1   MNIEEMKKIAAKEAL-KFIEDDMVIGLGTGSTTAYFIRLLGDMIKKGEVSDIVGVPTSYQ 59

Query: 60  AKQLIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIV 119
           ++ L I+ G+ +  L+    IDV +DGADEVD N+ LIKG G  L  EKII S +   IV
Sbjct: 60  SRLLAIESGIPVATLDQVDAIDVAVDGADEVDPNLNLIKGRGAALTMEKIIESRAGMFIV 119

Query: 120 IADYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNG 179
           + D  K    L    K  VPIEVIP A+  I  + +S++  E KLR  V K GPV+TDNG
Sbjct: 120 LVDERKLVDYLCQ--KMPVPIEVIPQAWRAIVEE-LSIFNAEAKLRMGVNKDGPVITDNG 176

Query: 180 NFILDWMF--ANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEG 227
           NFI+D  F   +  LD E   NT   IPGVVE G+F ++      G  EG
Sbjct: 177 NFIIDAKFPRIDDPLDMEIELNT---IPGVVENGIFADIADIVIVGTKEG 223


>UniRef50_A3H6Q6 Cluster: Ribose 5-phosphate isomerase; n=1;
           Caldivirga maquilingensis IC-167|Rep: Ribose 5-phosphate
           isomerase - Caldivirga maquilingensis IC-167
          Length = 229

 Score =  153 bits (370), Expect = 5e-36
 Identities = 92/230 (40%), Positives = 137/230 (59%), Gaps = 11/230 (4%)

Query: 8   QVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLK-VTCIPTSFQAKQLIIK 66
           ++AA +A  ++V +  + GVGSGST +  +  LAE +E   L  V  I TS + +  I+K
Sbjct: 4   KLAAAKAALKYVRSGYVIGVGSGSTALMFLSELAENIEGGGLTDVKLIATSTETEYEIVK 63

Query: 67  HGLNLGELETNP----NIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIAD 122
             L LGEL   P    ++DV IDGADEVD +  L+KGGGG L +EKII   + + IVI D
Sbjct: 64  --LGLGELLRYPWQVDHVDVAIDGADEVDKDKNLVKGGGGALTREKIIDYWASEFIVIVD 121

Query: 123 YTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFI 182
            +K   K+  ++   +P+EV+P A+  +K ++   YGG  +LR +  K GPV+TDNGN+I
Sbjct: 122 ESKLVDKIPSKHP--IPVEVVPYAWPLVKARLERDYGGSAELRYSSGKRGPVITDNGNYI 179

Query: 183 LDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNM-CCKAYFGQPEGNVVE 231
           +D+      ++  +    IK IPGVVE GLF  +   +   G+ +G+V E
Sbjct: 180 IDYR-PGSGIEPREGERVIKCIPGVVEVGLFNGLKVSRVIVGKQDGSVNE 228


>UniRef50_Q2FLE9 Cluster: Ribose 5-phosphate isomerase; n=2;
           Methanomicrobiales|Rep: Ribose 5-phosphate isomerase -
           Methanospirillum hungatei (strain JF-1 / DSM 864)
          Length = 235

 Score =  151 bits (367), Expect = 1e-35
 Identities = 84/216 (38%), Positives = 125/216 (57%), Gaps = 7/216 (3%)

Query: 4   EQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQL 63
           EQAK+ A Y+A D ++TN    G+G+GSTV + + RL ER+  E L +  IPTS Q    
Sbjct: 10  EQAKKRAGYKAAD-YITNGMTVGLGTGSTVAFTMARLKERMTEEGLLIVGIPTSIQTTMR 68

Query: 64  IIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADY 123
               G+ L  LE    ID+T+DGAD++D  M LIKG G   ++E+I+A  S +LI++AD 
Sbjct: 69  AGALGIPLIGLEQAEKIDITVDGADQIDPEMRLIKGRGAAHVRERIVADASTRLIIVADP 128

Query: 124 TKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFIL 183
           +    K+       +PIE+IP ++  +  ++  + GG + +R  V K GPV++DNGN IL
Sbjct: 129 S----KICSHLTGPIPIEIIPFSFSHVIRRLNEM-GGMVTVREGVKKDGPVISDNGNIIL 183

Query: 184 DWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCK 219
           D+   +   D   +   I +IPGVV  G+F     K
Sbjct: 184 DYTPVSIP-DPSALETAINMIPGVVSCGIFAEFTSK 218


>UniRef50_Q7U8K8 Cluster: Ribose-5-phosphate isomerase A; n=39;
           cellular organisms|Rep: Ribose-5-phosphate isomerase A -
           Synechococcus sp. (strain WH8102)
          Length = 239

 Score =  151 bits (366), Expect = 1e-35
 Identities = 90/234 (38%), Positives = 138/234 (58%), Gaps = 10/234 (4%)

Query: 5   QAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLK-VTCIPTSFQAKQL 63
           Q KQ  A  AV+Q + +  + G+GSGST    ++ L  ++ S +LK +  + TSFQ + L
Sbjct: 7   QMKQAVADAAVEQ-IKDGMVLGLGSGSTAALMIKALGAKLASGELKDIVGVTTSFQGEVL 65

Query: 64  IIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADY 123
             +  + L  L     ID+ IDGADEVD    LIKGGG C +QEK++A+ + + +V+   
Sbjct: 66  AAELNIPLLSLNAVDRIDLAIDGADEVDPGFQLIKGGGACHVQEKLVAARADRFVVVV-- 123

Query: 124 TKDSVKLGDRYKKG--VPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNF 181
             DS KL +R   G  +P+EV+P A+  ++ ++ +L GG+ +LR A  KAGPVVTD GN 
Sbjct: 124 --DSTKLVERLNLGFLLPVEVLPGAWRQVQQQLAAL-GGKAELRMAQRKAGPVVTDQGNL 180

Query: 182 ILDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQ-PEGNVVERSV 234
           +LD        D   + +T+  IPGV+E GLFV++  +   G+  +G+   RS+
Sbjct: 181 VLDVTMNGGISDPAALESTVNNIPGVLENGLFVDLVDEVLVGEITDGSAGVRSL 234


>UniRef50_Q6LY04 Cluster: Ribose-5-phosphate isomerase A; n=6;
           Euryarchaeota|Rep: Ribose-5-phosphate isomerase A -
           Methanococcus maripaludis
          Length = 239

 Score =  150 bits (364), Expect = 3e-35
 Identities = 90/221 (40%), Positives = 127/221 (57%), Gaps = 8/221 (3%)

Query: 4   EQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQL 63
           +  K   A QA  + V +  + G+GSGST    +Q L +RV  E+L +  +PTSF ++ +
Sbjct: 16  DSLKLKVAKQAA-KLVKDEMVVGLGSGSTANLFIQELGKRVVEEELYIYGVPTSFDSRMM 74

Query: 64  IIKHGLNLGELETNPNIDVTIDGADEV-DSNMTLIKGGGGCLLQEKIIASCSKKLIVIAD 122
               G+ L  L+    ID+ IDGADEV    ++LIKGGGGC   EKI+   +K+ +V+AD
Sbjct: 75  ASNSGIPLISLDQCGEIDIAIDGADEVCKKTLSLIKGGGGCHTMEKIVDYHAKEFVVLAD 134

Query: 123 YTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFI 182
             K    LGD  K  VP+EVIP AY  + NK++ +      +RS   K GPV+TDNGN I
Sbjct: 135 EGKLVESLGD--KTAVPLEVIPFAYSTVLNKLLDMNTAP-AIRSGSGKMGPVITDNGNMI 191

Query: 183 LDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFG 223
           +D +F N   D E+    +  IPGV+E G+F + C K   G
Sbjct: 192 ID-VFINIE-DAEETETMLNNIPGVLENGIF-SKCDKVLVG 229


>UniRef50_Q2CFA5 Cluster: Ribose 5-phosphate isomerase; n=2;
           Alphaproteobacteria|Rep: Ribose 5-phosphate isomerase -
           Oceanicola granulosus HTCC2516
          Length = 262

 Score =  150 bits (363), Expect = 3e-35
 Identities = 94/240 (39%), Positives = 142/240 (59%), Gaps = 13/240 (5%)

Query: 3   LEQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQ 62
           +++AK  AA +A D +V +    G+G+GST  + V+ L E V  + L++T +PTS +   
Sbjct: 8   IDKAKFAAARRATD-YVEDGMRVGLGTGSTAAWLVKCLGEMVREDGLRLTGVPTSSRTAA 66

Query: 63  LIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIAD 122
           L  + G+ +  L+    +D+TIDGADE DSN+ LIKGGGG LLQEKI+A+ S +++VIAD
Sbjct: 67  LAREVGIKVVSLDEARWLDLTIDGADEYDSNLNLIKGGGGALLQEKIVATASDQMVVIAD 126

Query: 123 YTKDSVKLGDRYKKGVPIEVIPMAY----VPIKNKIISL--YGGEIKLRSAVAKAGPVVT 176
            +K    LG      +P+EVIP  +    V I+  +I L   G +  LR  +    P VT
Sbjct: 127 ISKQVDTLG---AFPLPVEVIPFGWQTTKVLIEETLIGLDVLGRDTSLR--LNGERPYVT 181

Query: 177 DNGNFILDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGNVVERSVIE 236
           D GN+ILD +  N+  +  +++  +  IPGVVE GLF+++C     G  +G V  R + E
Sbjct: 182 DEGNYILD-LHLNRIGNARQLSLVLNQIPGVVENGLFIDVCDAVVIGYGDGRVEVRDINE 240


>UniRef50_Q5UZD7 Cluster: Ribose-5-phosphate isomerase A; n=2;
           cellular organisms|Rep: Ribose-5-phosphate isomerase A -
           Haloarcula marismortui (Halobacterium marismortui)
          Length = 228

 Score =  147 bits (356), Expect = 2e-34
 Identities = 92/227 (40%), Positives = 136/227 (59%), Gaps = 10/227 (4%)

Query: 4   EQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQL 63
           + AKQ A   A +  V +  + G+G+GST  YA++ + + V++  L V  +PTSFQ++QL
Sbjct: 7   DAAKQAAGESAAEA-VEDATVVGLGTGSTAAYAIRAIGQAVDAG-LDVVGVPTSFQSRQL 64

Query: 64  IIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADY 123
               G+ L +L+ + ++D+ IDGADEV S   LIKGGG    +EKI+ + + + +V+AD 
Sbjct: 65  ARDCGIPLADLD-DVSVDLAIDGADEVASG-NLIKGGGAAHAREKIVDASADRFLVVADP 122

Query: 124 TKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFIL 183
           TK++  L   Y   VP+EV+PMA   +   +  L GG+  LR A  K GPVVTDNGN +L
Sbjct: 123 TKEAAVLS--YP--VPVEVLPMARSTVVTAVEEL-GGDPTLRRAERKDGPVVTDNGNLVL 177

Query: 184 DWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGNVV 230
           D  F N   D   + + +  +PGVVE GLFV M  + + G  +G  V
Sbjct: 178 DCDF-NSIHDPAALASDLAALPGVVEHGLFVGMADEIHVGTADGVTV 223


>UniRef50_Q7R8N6 Cluster: Ribose 5-phosphate isomerase; n=6;
           Plasmodium|Rep: Ribose 5-phosphate isomerase -
           Plasmodium yoelii yoelii
          Length = 238

 Score =  146 bits (355), Expect = 3e-34
 Identities = 85/233 (36%), Positives = 137/233 (58%), Gaps = 9/233 (3%)

Query: 3   LEQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLK-VTCIPTSFQAK 61
           ++  K++ AY+AVD++V +N   G+G+GSTV Y ++R+   ++S K+K + C+PTS   +
Sbjct: 1   MDSLKKIVAYKAVDEYVQSNMTIGLGTGSTVFYVIERIDALMKSGKIKNLICVPTSIDTE 60

Query: 62  QLIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIA 121
                 G+ L  L  N  ID+ IDGADE+DS++ LIKG GG L++EK++A  +   I+I 
Sbjct: 61  IKAKSLGIPLTSLTKNLKIDIAIDGADEIDSDLNLIKGRGGALVREKLVAGNASCFIIIV 120

Query: 122 DYTKDSVKLGDRYKKGVPIEVIPMAY-VPIKN--KIISLYGGEIKLRSAVAKAGPV-VTD 177
           D +K   + G      VPIE++   Y + I+N  KI +L     +LR    K G + +TD
Sbjct: 121 DESK-MCEDGLGTTGAVPIEILSFGYEIIIENLLKISALKNCIYRLRE---KNGEIFITD 176

Query: 178 NGNFILDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGNVV 230
           N N+I+D+ F N   +  +    IK+  GV++ G+FVNM   A   +  G ++
Sbjct: 177 NNNYIVDFFFDNPIENLAQTCEQIKMTTGVIDHGIFVNMASIALISKINGTIL 229


>UniRef50_Q5G570 Cluster: Ribose 5-phosphate isomerase-like protein;
           n=4; Pezizomycotina|Rep: Ribose 5-phosphate
           isomerase-like protein - Magnaporthe grisea (Rice blast
           fungus) (Pyricularia grisea)
          Length = 297

 Score =  146 bits (354), Expect = 4e-34
 Identities = 92/228 (40%), Positives = 125/228 (54%), Gaps = 17/228 (7%)

Query: 3   LEQAKQVAAYQAV-DQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAK 61
           +E AK+ AA+ AV D         G+GSGSTVVY V+ + E        +T  PT  Q+K
Sbjct: 17  IEMAKKAAAFTAVKDHLDPRYTHVGIGSGSTVVYVVEAIKELHPEASKDMTFYPTGDQSK 76

Query: 62  QLIIKHGLNLGELETNPN---IDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLI 118
            LI   GL    +E  P    +DV  DGADE D+++ LIKGGGGCL QEKI+A  S+  +
Sbjct: 77  GLIKAGGLRAAPIEDRPQGSLLDVYFDGADEADADLNLIKGGGGCLWQEKIVAVASRTFV 136

Query: 119 VIADYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDN 178
            I D+ K S  LG ++K+G+PIEV+P A   +  ++  L     +LRS   KAG VVTDN
Sbjct: 137 CIGDFRKLSRNLGTQWKQGIPIEVLPKAADHVLAELERLGAHSPRLRSGSGKAGSVVTDN 196

Query: 179 GNFILDWMF-----------ANQNLDW--EKVNNTIKLIPGVVETGLF 213
           G  I+D  F             +N  W  +++   +K + GV E GLF
Sbjct: 197 GMHIIDAPFTPLLLAGDEGGTGENGIWSVDRLAAKLKSLVGVCEIGLF 244


>UniRef50_A6LDT5 Cluster: Putative ribose 5-phosphate isomerase;
           n=2; Bacteroidales|Rep: Putative ribose 5-phosphate
           isomerase - Parabacteroides distasonis (strain ATCC 8503
           / DSM 20701 / NCTC11152)
          Length = 234

 Score =  145 bits (352), Expect = 7e-34
 Identities = 79/198 (39%), Positives = 120/198 (60%), Gaps = 8/198 (4%)

Query: 19  VTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIKHGLNLGELETNP 78
           V N  + GVGSGST   A+ R+AER+  E L +  IPTS + +    + G+ +  L ++ 
Sbjct: 34  VENGQVIGVGSGSTSYLALTRIAERIRMEHLSILAIPTSLEIRMTCAQLGIPVTSLFSHK 93

Query: 79  NIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTKDSVKLGDRYKKGV 138
             D T DGADEVDS+  LIKG GG + +EK++ S S +  ++ D +K   +LG ++   +
Sbjct: 94  P-DWTFDGADEVDSHFNLIKGRGGAMFKEKLLISSSPQTYILVDPSKKVERLGAKFP--I 150

Query: 139 PIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFILD-WMFANQNLDWEKV 197
           P+E+ P A   +++++  L   EIKLR    K GP++T+NGN ILD WM    +   E  
Sbjct: 151 PVEIFPEALTHVEDRLHRLNPREIKLRMGQGKDGPIITENGNMILDVWM----DYIPENT 206

Query: 198 NNTIKLIPGVVETGLFVN 215
            +T+K I GV+E+GLF+N
Sbjct: 207 ESTLKSITGVLESGLFIN 224


>UniRef50_O83625 Cluster: Ribose-5-phosphate isomerase A; n=2;
           Treponema|Rep: Ribose-5-phosphate isomerase A -
           Treponema pallidum
          Length = 254

 Score =  143 bits (347), Expect = 3e-33
 Identities = 88/238 (36%), Positives = 131/238 (55%), Gaps = 15/238 (6%)

Query: 7   KQVAAYQAVDQFVTNNCI-----FGVGSGSTVVYAVQRLAERVESEKLK-VTCIPTSFQA 60
           K + A ++VD  V    +      G+G+GST + AV+R+A+ +    L  +  +PTSFQ 
Sbjct: 18  KLLVAQRSVDTLVQEGVLHAHMSIGLGTGSTAMPAVKRIADHLARGTLSDIAAVPTSFQT 77

Query: 61  KQLIIKHGLNLGELETNP---NIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKL 117
             +  ++ + L  L +      +DVTIDGADE+D+   +IKGGG  LLQEKI A  S   
Sbjct: 78  ALICERYNIPLFSLSSKRIGGKLDVTIDGADEIDTQNFVIKGGGAALLQEKIAAYNSAHF 137

Query: 118 IVIADYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTD 177
           ++I D TK    LG R    +PIEV+P A + +  + +  +G  + +R AV K GPVVTD
Sbjct: 138 VIIVDETKVVETLGTR--AALPIEVVPEARMSVM-RTLQDWGLSVHIREAVRKKGPVVTD 194

Query: 178 NGNFILD--WMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGNVVERS 233
           +GNFILD  W         + +   +  +PGV+E GLF     + +    +G+V ERS
Sbjct: 195 HGNFILDARWQSLPTRTP-QDMERALNALPGVIENGLFTERTVRVFVAHADGSVEERS 251


>UniRef50_O29319 Cluster: Ribose-5-phosphate isomerase A; n=1;
           Archaeoglobus fulgidus|Rep: Ribose-5-phosphate isomerase
           A - Archaeoglobus fulgidus
          Length = 225

 Score =  142 bits (345), Expect = 5e-33
 Identities = 79/199 (39%), Positives = 123/199 (61%), Gaps = 9/199 (4%)

Query: 17  QFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIKHGLNLGEL-E 75
           + V +  + G+GSGSTV   +  L +++  E L++  IP+S+Q+    I++G+ + +L E
Sbjct: 15  ELVKDGMVLGIGSGSTVEVFLNLLGDKIREEGLEIYGIPSSYQSYFAAIRNGVEIVDLVE 74

Query: 76  TNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTKDSVKLGDRYK 135
             P  D+ IDGAD+VD+ +  IKGGGG + +EKI+A  S+K+++I D +    KL ++  
Sbjct: 75  FEP--DLCIDGADQVDAKLNCIKGGGGAMTREKIVAKASRKVVIIVDES----KLVEKLS 128

Query: 136 KGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFILDWMFANQNLD-W 194
             VP+EV+P AY  +  +I  + G + +LR    K GPV+TDNGNF++D  F     D  
Sbjct: 129 MPVPVEVLPFAYGWVLREIEKM-GCKARLREGKGKIGPVITDNGNFVVDCDFGVIEEDRV 187

Query: 195 EKVNNTIKLIPGVVETGLF 213
           E +   IKLI GVVE G+F
Sbjct: 188 EGLEGEIKLISGVVENGIF 206


>UniRef50_Q2JK16 Cluster: Ribose 5-phosphate isomerase A; n=7;
           cellular organisms|Rep: Ribose 5-phosphate isomerase A -
           Synechococcus sp. (strain JA-2-3B'a(2-13))
           (Cyanobacteria bacteriumYellowstone B-Prime)
          Length = 238

 Score =  142 bits (344), Expect = 7e-33
 Identities = 87/227 (38%), Positives = 132/227 (58%), Gaps = 7/227 (3%)

Query: 2   SLEQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAK 61
           SL+  KQ AA  AV Q V +  + G+G+GST  +AV  LAER+++E L++  +PTS +  
Sbjct: 11  SLDDLKQAAARAAV-QKVQSGMVVGLGTGSTAAFAVSALAERMQTEGLQIIGVPTSERTA 69

Query: 62  QLIIKHGLNLGELETNPNIDVTIDGADEVD-SNMTLIKGGGGCLLQEKIIASCSKKLIVI 120
           +     G+ L  LE  P +D+ IDGADE++  ++ LIKG GG LL+EK++ + + +LI+I
Sbjct: 70  EQARSLGIPLATLEEQPRLDLAIDGADEIEVGSLNLIKGAGGALLREKLVEASAAELIII 129

Query: 121 ADYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGN 180
           AD +K   +LG R+   VP+EV+   +     ++ +L G    LR   A   P +TD  +
Sbjct: 130 ADASKKVAQLGIRFP--VPVEVVRFGWKTTLARVEAL-GCTATLRRN-ANGDPYLTDEQH 185

Query: 181 FILDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEG 227
           +ILD  F     D  K+ + +K   GVVE GLF+ M  +A    P G
Sbjct: 186 YILDCQFGPM-ADPAKIADQLKGTVGVVEHGLFIGMAKEAIIALPTG 231


>UniRef50_Q5LTT5 Cluster: Ribose-5-phosphate isomerase A; n=28;
           Alphaproteobacteria|Rep: Ribose-5-phosphate isomerase A
           - Silicibacter pomeroyi
          Length = 262

 Score =  141 bits (342), Expect = 1e-32
 Identities = 88/236 (37%), Positives = 137/236 (58%), Gaps = 9/236 (3%)

Query: 3   LEQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQ 62
           +++AK VAA +A D  V +    G+G+GST  + V+ L + V  E LK+  +PTS +  Q
Sbjct: 8   IDKAKFVAAKRAAD-LVEDGMRVGLGTGSTAAWLVRCLGDMVRKEGLKMRGVPTSTRTAQ 66

Query: 63  LIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIAD 122
           L  + G+ +  L+    +D+TIDGADE D ++ LIKGGGG LLQEKI+A+ S +++VIAD
Sbjct: 67  LAREVGIEVITLDEARWLDITIDGADEFDGDLNLIKGGGGALLQEKIVATASDQMVVIAD 126

Query: 123 YTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKI-ISLYGGEIKLRSAVAKAG---PVVTDN 178
             K+  +LG      +P+EVIP  +   +  +  +L   ++  R+A  +     P VTD 
Sbjct: 127 LGKEVSRLG---AFPLPVEVIPFGWQTTQALLEETLISMDVLGRTATLRMNGDTPFVTDE 183

Query: 179 GNFILDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGNVVERSV 234
           GN ILD +   +  +  ++   +  IPGVVE GLF+++C     G  +G V  R +
Sbjct: 184 GNHILD-LHLQRIGNARQLALVLNQIPGVVENGLFIDICDTVVVGHGDGRVEIRDI 238


>UniRef50_A7I6S5 Cluster: Ribose 5-phosphate isomerase; n=1;
           Candidatus Methanoregula boonei 6A8|Rep: Ribose
           5-phosphate isomerase - Methanoregula boonei (strain
           6A8)
          Length = 237

 Score =  140 bits (339), Expect = 3e-32
 Identities = 83/211 (39%), Positives = 121/211 (57%), Gaps = 8/211 (3%)

Query: 6   AKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLII 65
           AK+ A YQA +  V +  + G+G+GSTV YA++ L+ R+  + L V  +PTS+Q      
Sbjct: 11  AKRAAGYQAAEM-VEDGMVIGLGTGSTVFYAIECLSGRIR-DGLSVVGVPTSYQTAMKAR 68

Query: 66  KHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTK 125
           ++G+ L  L+ NP +D+ IDGAD+ D    LIKG G  + +EK +AS + + IV+ D  K
Sbjct: 69  EYGIPLTTLDDNPVLDLAIDGADQADPQFRLIKGRGAAITREKCVASAAFRFIVVVDEAK 128

Query: 126 DSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFILDW 185
              KL       VP+E +P A      ++  L G    +R AV K GPV+TDNGNFI+D 
Sbjct: 129 MVKKLAG----VVPVETLPFATKTALAQLRGL-GCRPFIREAVKKDGPVITDNGNFIVDC 183

Query: 186 MFANQNLDWEKVNNTIKLIPGVVETGLFVNM 216
            F  +  D   +   I  IPGV+E+GLF  +
Sbjct: 184 QF-EEIPDPALLEAGIAAIPGVIESGLFTRL 213


>UniRef50_Q8EMZ1 Cluster: Ribose-5-phosphate isomerase A 2; n=1;
           Oceanobacillus iheyensis|Rep: Ribose-5-phosphate
           isomerase A 2 - Oceanobacillus iheyensis
          Length = 224

 Score =  139 bits (337), Expect = 5e-32
 Identities = 81/214 (37%), Positives = 130/214 (60%), Gaps = 8/214 (3%)

Query: 7   KQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIK 66
           KQ+AA +AV +++ +  + G+GSGSTV   +  LA R+  E+L+V  IP S ++++L  +
Sbjct: 6   KQIAAQEAV-RYIKDGMVIGIGSGSTVNEFLYCLAARMRKERLQVVGIPASKKSERLATE 64

Query: 67  HGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTKD 126
            G+ L    T  N+D+ IDG DE+D  + L+KGGGG L++EK+I   ++  IVIA   K 
Sbjct: 65  LGIPLTTFATYQNVDIAIDGTDEIDDQLYLVKGGGGSLVREKMIDLVAETFIVIASGKKK 124

Query: 127 SVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFILDWM 186
             KLG      VP+EV+P  +   + + +  +G +  LR  + +    V+DN N+I+D  
Sbjct: 125 IKKLG---SFPVPVEVVPFGWQATEQR-LQQFGCQTNLR--MVEEDIFVSDNQNYIIDCD 178

Query: 187 FANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKA 220
           F   + D E ++ ++K I GV+ETG+F+NM  KA
Sbjct: 179 FKEID-DAEALHRSLKQIVGVIETGIFINMVDKA 211


>UniRef50_A7P3I3 Cluster: Chromosome chr1 scaffold_5, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr1 scaffold_5, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 683

 Score =  138 bits (333), Expect = 1e-31
 Identities = 78/220 (35%), Positives = 130/220 (59%), Gaps = 7/220 (3%)

Query: 1   MSLEQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLK-VTCIPTSFQ 59
           ++ ++ K++AAY+AV+ +V +  + G+G+GST  +AV R+ E +   KLK +  IPTS +
Sbjct: 450 LTQDELKKIAAYKAVE-YVESGMVLGLGTGSTAKHAVDRIGELLRQGKLKNIVGIPTSKK 508

Query: 60  AKQLIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIV 119
             +  +  G+ L +L+++P +D+ IDGADEVD  + L+KG GG LL+EK++    KK IV
Sbjct: 509 THEQAVSLGIPLSDLDSHPILDLAIDGADEVDPYLNLVKGRGGSLLREKMVEGACKKFIV 568

Query: 120 IADYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLY---GGEIKLRSAVAKAGPVVT 176
           I D +K    LG      +P+E++P  +     ++   +   G   KLR+      P VT
Sbjct: 569 IVDESKLVNHLGGS-GLAMPVEIVPFCWKFTAQRLQMFFEESGCVAKLRT-YENGEPFVT 626

Query: 177 DNGNFILDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNM 216
           DN N+++D  F  +  D +  ++ I  + GVVE G+F+ M
Sbjct: 627 DNRNYVVDLYFKREIGDLKVASDAILRLAGVVEHGMFLGM 666


>UniRef50_Q5FQ98 Cluster: Ribose-5-phosphate isomerase A; n=4;
           Bacteria|Rep: Ribose-5-phosphate isomerase A -
           Gluconobacter oxydans (Gluconobacter suboxydans)
          Length = 231

 Score =  136 bits (329), Expect = 5e-31
 Identities = 87/223 (39%), Positives = 128/223 (57%), Gaps = 9/223 (4%)

Query: 7   KQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIK 66
           K+ AA +A D  V +  + G+G+GST  Y ++RL ERV +E L++  IPTS  ++   +K
Sbjct: 10  KRTAAREAADM-VKSGMVVGLGTGSTAAYMIERLGERV-AEGLEIFGIPTSDDSEDKALK 67

Query: 67  HGLNLGELETNPNIDVTIDGADEVD-SNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTK 125
            G+ L +   +  ID+ IDGADEV   ++ LIKG GG LL+EKI+A  +K+ +VI D TK
Sbjct: 68  AGIPLTDFSAHRRIDIAIDGADEVQRGSLNLIKGLGGALLREKIVAQAAKRFVVIVDGTK 127

Query: 126 DSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPV-VTDNGNFILD 184
               LG+R    VP+EVI   +     ++ +     +K R+   +AG + VTD GN ILD
Sbjct: 128 PVDLLGER--APVPVEVISFGWECTAERLAACGARGVKPRT--DRAGSLFVTDTGNMILD 183

Query: 185 WMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEG 227
             F       E++   I  I GVVE G+F+NM  +     P+G
Sbjct: 184 CHFGPIEKP-EELAEKIDRIVGVVEHGMFLNMASEVLVATPDG 225


>UniRef50_UPI0000E87CBD Cluster: ribose-5-phosphate isomerase A;
           n=1; Methylophilales bacterium HTCC2181|Rep:
           ribose-5-phosphate isomerase A - Methylophilales
           bacterium HTCC2181
          Length = 224

 Score =  135 bits (327), Expect = 8e-31
 Identities = 75/211 (35%), Positives = 123/211 (58%), Gaps = 6/211 (2%)

Query: 7   KQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIK 66
           K++ A  A+D +V NN I G+G+GST    +  LA+++ +E L +  + +S    +    
Sbjct: 4   KELVADAALD-YVKNNSIVGLGTGSTADIFINALAKKISAESLNIKVVASSTSTHEKANA 62

Query: 67  HGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTKD 126
            GLN   ++    +D+ IDGADE+  N+ ++KG G  L++EKI+A  SK  IVI D +K 
Sbjct: 63  AGLNYISIDQITELDLYIDGADEITENLDILKGRGYDLVREKILARASKSFIVIGDQSKI 122

Query: 127 SVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFILDWM 186
             K+G++Y   +PIE+ P+A+  I   ++     + ++R  + K    +T  GN++LD  
Sbjct: 123 VSKIGEKY--SIPIEITPIAW-KITKILVEKLAIKCEVRENLTKNAFAITSYGNYVLDCE 179

Query: 187 FANQNLDWEKVNNTIKLIPGVVETGLFVNMC 217
           F   NL  +K+ + I  IPGV E GLF++MC
Sbjct: 180 FNETNL--KKLGDEIASIPGVFEHGLFIDMC 208


>UniRef50_Q5WCM4 Cluster: Ribose-5-phosphate isomerase A; n=1;
           Bacillus clausii KSM-K16|Rep: Ribose-5-phosphate
           isomerase A - Bacillus clausii (strain KSM-K16)
          Length = 228

 Score =  134 bits (324), Expect = 2e-30
 Identities = 82/225 (36%), Positives = 133/225 (59%), Gaps = 9/225 (4%)

Query: 3   LEQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQ 62
           ++Q K++AA +A  ++V +    G+GSGSTV   V+ L E+ + E L +  +  S + + 
Sbjct: 1   MDQLKRMAA-EAAAEYVKDGMKIGLGSGSTVFEFVRVLGEKAK-EGLNIQAVAASRKTEA 58

Query: 63  LIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIAD 122
           L    G+++ +  T   ++V  DGADE+   + L+KGGGG LL+EK++A+ +K+L+V+AD
Sbjct: 59  LAKACGIHIIDFPTMEKLEVAFDGADEIAPGLMLLKGGGGSLLREKLVAAAAKRLVVLAD 118

Query: 123 YTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFI 182
            +K   +LG  +K  +P+E+IP  +     +I +L GG   LR       P V+DN N+I
Sbjct: 119 ESKLVEELG-AFK--LPVEIIPFGWETTAMRIEAL-GGVASLRQ--TGKSPFVSDNHNWI 172

Query: 183 LDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEG 227
           LD  F N   D   ++  +K + GVVETGLF++M C+A      G
Sbjct: 173 LDCDFGNIR-DPYSLHEKVKKLVGVVETGLFLDMACEAIVASKNG 216


>UniRef50_Q1GX07 Cluster: Ribose 5-phosphate isomerase; n=1;
           Sphingopyxis alaskensis|Rep: Ribose 5-phosphate
           isomerase - Sphingopyxis alaskensis (Sphingomonas
           alaskensis)
          Length = 228

 Score =  132 bits (320), Expect = 6e-30
 Identities = 80/209 (38%), Positives = 127/209 (60%), Gaps = 9/209 (4%)

Query: 7   KQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIK 66
           K +AA +AVD+ V +  + G+G+GST  YAV+ L+ER++   L++T + TS   + L ++
Sbjct: 8   KSIAAVRAVDE-VRDGMLVGLGTGSTAAYAVKSLSERIK-HGLRITAVATSQATEALALR 65

Query: 67  HGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTKD 126
             + L   +    +D+TIDGADE+D     IKGGGG LL+EKI  S S ++I+IAD +K 
Sbjct: 66  LAVPLVPFQQLSAVDLTIDGADEIDDRFQAIKGGGGALLREKITESASTRVIIIADSSKL 125

Query: 127 SVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFILDWM 186
             +LG   K  +P+EV+P A   ++ ++ +L G  + +R   A   P +TD GN+ILD  
Sbjct: 126 VAQLG---KFPLPVEVVPFATEFVRARLSAL-GARVTVRE--AGGTPFLTDQGNYILD-A 178

Query: 187 FANQNLDWEKVNNTIKLIPGVVETGLFVN 215
             ++     ++   I  IPGV+E GLF++
Sbjct: 179 ALDEIPRPREIAAAITTIPGVLEHGLFLD 207


>UniRef50_A7AMM8 Cluster: Ribose 5-phosphate isomerase A family
           protein; n=1; Babesia bovis|Rep: Ribose 5-phosphate
           isomerase A family protein - Babesia bovis
          Length = 240

 Score =  132 bits (320), Expect = 6e-30
 Identities = 80/232 (34%), Positives = 133/232 (57%), Gaps = 6/232 (2%)

Query: 1   MSLEQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLK-VTCIPTSFQ 59
           M  ++  + AA  AVD ++ N  I G+G+GST  YAV+ LA+++ + KL+ VT + TS  
Sbjct: 1   MDRQECMRRAAEFAVDTYIQNGMIVGLGTGSTASYAVRYLAKQLSAAKLRDVTAVATSVA 60

Query: 60  AKQLIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIV 119
             +L+ + G+   E + + +IDV IDGAD +D ++ LIKGGGG L +EK++   ++K+I+
Sbjct: 61  TFRLMSELGIPSLEFDDSVSIDVAIDGADAIDGDLNLIKGGGGALFREKLVELGARKVII 120

Query: 120 IADYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIK--LRSAVAKAGPVVTD 177
           IAD TK  VK        VP+E++   +V   ++I+S  G  ++   +   A     +TD
Sbjct: 121 IADGTK-KVKGHLLQAFHVPVEIVQFGHVVTISRILSRVGPHVRSWTKRMNADGSLYLTD 179

Query: 178 NGNFILDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGNV 229
           N N I+D  F   +L    ++  ++ + GVV TGLF+ +         +GN+
Sbjct: 180 NNNVIMDIEFGPTDL--PNLDFELRSVHGVVCTGLFLGIASTVVIAHSDGNL 229


>UniRef50_A3XMJ2 Cluster: Ribose 5-phosphate isomerase; n=1;
           Leeuwenhoekiella blandensis MED217|Rep: Ribose
           5-phosphate isomerase - Leeuwenhoekiella blandensis
           MED217
          Length = 224

 Score =  131 bits (317), Expect = 1e-29
 Identities = 84/232 (36%), Positives = 136/232 (58%), Gaps = 9/232 (3%)

Query: 1   MSLEQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQA 60
           M+ +Q K+ AA +AV +++ +N + G+G+GST  + ++ +   V ++ + +TC+P+S   
Sbjct: 1   MTADQEKKQAALEAV-KYIEDNMVVGLGTGSTAKHMIEAVGALV-AKGMNLTCVPSSDAT 58

Query: 61  KQLIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVI 120
           ++L  + G+ +  L+    IDVTIDGADE D+N  LIKGGGG LL+EKI+A  +K  I+I
Sbjct: 59  EKLAKELGIKIVALDEIEKIDVTIDGADEFDANFQLIKGGGGALLREKILAWNTKFNIII 118

Query: 121 ADYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGN 180
           AD +KD  KLG  +K  +P+EVIP A    K  I  L    +K    +    P  TD  N
Sbjct: 119 ADSSKDVEKLG-AFK--LPLEVIPFA---TKQIITFLEEEGLKPVQRMKGNDPYRTDENN 172

Query: 181 FILDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGNVVER 232
            I+D      + D + +   +  +PG+VETGLF++       G+ +G  +++
Sbjct: 173 NIVDVDIFEVD-DLKALEIKLLKVPGIVETGLFLDTTSLIIVGKEDGPEIKK 223


>UniRef50_Q9HN33 Cluster: Ribose-5-phosphate isomerase A; n=3;
           Halobacteriaceae|Rep: Ribose-5-phosphate isomerase A -
           Halobacterium salinarium (Halobacterium halobium)
          Length = 225

 Score =  131 bits (316), Expect = 2e-29
 Identities = 83/226 (36%), Positives = 130/226 (57%), Gaps = 13/226 (5%)

Query: 2   SLEQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAK 61
           S EQ K+ A   AV + VT   + G+G+GSTV +A++ L     +E   V+ + TSF+++
Sbjct: 7   SAEQ-KRRAGEAAVAEEVTEGAVVGLGTGSTVAHAIRALG----AEASDVSGVATSFESR 61

Query: 62  QLIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIA 121
           +  +  G+ +  LE   ++DV IDGAD+V   + L+KGGG    +EK +A+ + + +V+A
Sbjct: 62  RRAVDAGVTVTSLEA-ASVDVAIDGADQVADGV-LVKGGGAAHTREKYVAASADRFVVVA 119

Query: 122 DYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNF 181
           D +K+S    D     VP+ V+P A+  + +++ +L GG   LR A  K GPVVTD G+ 
Sbjct: 120 DPSKES----DVVDVPVPVAVVPDAWPVVVDRVEAL-GGTATLRDAERKDGPVVTDTGSL 174

Query: 182 ILDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEG 227
           ++D  F       E V  ++  +PGVVE GLFV M    Y G  +G
Sbjct: 175 VVDCDFGAIETP-EAVAASLSAVPGVVEHGLFVGMADAVYVGTDDG 219


>UniRef50_Q9RW24 Cluster: Ribose-5-phosphate isomerase A; n=4;
           Deinococci|Rep: Ribose-5-phosphate isomerase A -
           Deinococcus radiodurans
          Length = 226

 Score =  131 bits (316), Expect = 2e-29
 Identities = 81/228 (35%), Positives = 133/228 (58%), Gaps = 9/228 (3%)

Query: 1   MSLEQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLK-VTCIPTSFQ 59
           M LE  K+ AA ++V   V +    G+G+GST  YA++ L  ++ + +L  +  + TS  
Sbjct: 1   MDLEALKKEAALRSV-ALVQSGQRVGLGTGSTAKYAIEELGRKLAAGELSGIVGVSTSEA 59

Query: 60  AKQLIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIV 119
           +++L  + G+    L+  P +D+ IDGADE+  N+ L+KG GG L++EK+    +K+LI+
Sbjct: 60  SEKLAREVGIPTEPLDPRP-LDIAIDGADEIAPNLDLVKGLGGALVREKMTEVQAKRLII 118

Query: 120 IADYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNG 179
           IAD+TK   +LG+  K  +PIE++P  ++    ++     G  +LR   A+  P VTDNG
Sbjct: 119 IADHTKLVTRLGE--KAPLPIEIVPFGFLSTIERLREFLPGG-RLRQPGAQ--PYVTDNG 173

Query: 180 NFILDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEG 227
           N+I D     +  D  ++   IK   GVV+TGLF+ M  +A+   P+G
Sbjct: 174 NYIFDAQLPAE-FDARELERRIKGTLGVVDTGLFLGMAERAFVAAPDG 220


>UniRef50_Q6N8C3 Cluster: Ribose-5-phosphate isomerase A; n=6;
           Alphaproteobacteria|Rep: Ribose-5-phosphate isomerase A
           - Rhodopseudomonas palustris
          Length = 232

 Score =  129 bits (312), Expect = 5e-29
 Identities = 90/239 (37%), Positives = 134/239 (56%), Gaps = 13/239 (5%)

Query: 1   MSLEQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQA 60
           M  E+ K+ AA +A+++ V      G+G+GST  + V+ L ERV    L++  +PTS   
Sbjct: 1   MDKEELKRRAAARALEE-VRGGMKLGLGTGSTAKHFVELLGERVRLG-LEIIGVPTSEVT 58

Query: 61  KQLIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVI 120
           +    + G+ L  L+    +D+TIDGADEVD ++ LIKGGGG LL+EKI+A+ S ++IVI
Sbjct: 59  RADAERCGIRLTSLDEIDRLDITIDGADEVDHHLDLIKGGGGALLREKIVAAASDRMIVI 118

Query: 121 ADYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLY-----GGEIKLRSAVAKAGPVV 175
           AD +K    LG R+   +PIEVIP      +  + + +      GE+KLR         V
Sbjct: 119 ADESKLVDTLG-RFP--LPIEVIPFGLGATRRALQNAFTAAGCDGELKLRPG-KDGHAFV 174

Query: 176 TDNGNFILDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEG-NVVERS 233
           TD G++ILD     +  D  ++   + +IPGVVE GLFV M         +G   +ER+
Sbjct: 175 TDGGHWILDAQL-GRIPDAPRLAQLLSVIPGVVEHGLFVGMASTVVLAGADGIRTIERA 232


>UniRef50_Q0SCN2 Cluster: Ribose-5-phosphate isomerase; n=1;
           Rhodococcus sp. RHA1|Rep: Ribose-5-phosphate isomerase -
           Rhodococcus sp. (strain RHA1)
          Length = 252

 Score =  129 bits (311), Expect = 7e-29
 Identities = 81/229 (35%), Positives = 124/229 (54%), Gaps = 10/229 (4%)

Query: 4   EQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQL 63
           + AK      AV+++  +    G+GSG+T  + V+ L E+V ++ L V  +PTS   + L
Sbjct: 9   DAAKYAVGRAAVERYAHDGAQLGLGSGTTSAWFVRALGEKV-ADGLDVVGVPTSTATRDL 67

Query: 64  IIKHGLNLGEL-ETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIAD 122
            +  G+ L +L + +  +DVT+DG DEVD +  +IKGGG CLL E+++A  S K++ IAD
Sbjct: 68  ALSVGITLVDLNDLDRPLDVTLDGPDEVDHDGDMIKGGGACLLWERMVAEASSKMVCIAD 127

Query: 123 YTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGG----EIKLRSAVAKAGPVVTDN 178
            TK   +LG      +PIEVIP  +   +  I +L       ++K+        PVVTD+
Sbjct: 128 DTKLVEQLG---SFPLPIEVIPFGWKATRRSISALLTDLGYTDVKIIQRHRNGQPVVTDS 184

Query: 179 GNFILDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEG 227
           GNFILD        D   ++  +  I GVVE GLF  +  +     P+G
Sbjct: 185 GNFILDAHMV-AITDKALLDTNLNWIAGVVENGLFTGIAHEILIASPDG 232


>UniRef50_A7D0F8 Cluster: Ribose 5-phosphate isomerase; n=1;
           Halorubrum lacusprofundi ATCC 49239|Rep: Ribose
           5-phosphate isomerase - Halorubrum lacusprofundi ATCC
           49239
          Length = 240

 Score =  128 bits (310), Expect = 9e-29
 Identities = 85/240 (35%), Positives = 137/240 (57%), Gaps = 19/240 (7%)

Query: 4   EQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQL 63
           + AK+ A   A +  VT+  + G+G+GST  +A++RL +RV+S  L +  + TSF +++L
Sbjct: 8   DAAKRRAGESAAET-VTDGEVVGLGTGSTAAHAIRRLGDRVDSG-LDIRGVATSFASREL 65

Query: 64  IIKHGLNLGELETN-----PNIDVTIDGADEV-----DSNM-TLIKGGGGCLLQEKIIAS 112
             + G+ L +L+         ID+ IDGAD+V     +S +  LIKGGG    +EK++ +
Sbjct: 66  AAECGIPLLDLDEAVGSDATGIDIAIDGADQVAVGEGESEVGPLIKGGGAAHAREKLVDA 125

Query: 113 CSKKLIVIADYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAG 172
            + + +V+AD +K++  L     + VP+EV+P     +   + +  GGE  LR A  K G
Sbjct: 126 SADRFLVVADPSKETPVLN----RSVPVEVLPAGRSAVAEAVRAA-GGEPTLRRAERKDG 180

Query: 173 PVVTDNGNFILDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGNVVER 232
           PVVTDNGN +LD  F  +  D + ++ T+   PGVVE G+FV +  + + G   G  V R
Sbjct: 181 PVVTDNGNLVLDCAF-GEIADPDALSTTLSTTPGVVEHGIFVGLADEVHVGTETGVRVAR 239


>UniRef50_Q6MC00 Cluster: Ribose-5-phosphate isomerase A; n=1;
           Candidatus Protochlamydia amoebophila UWE25|Rep:
           Ribose-5-phosphate isomerase A - Protochlamydia
           amoebophila (strain UWE25)
          Length = 232

 Score =  128 bits (310), Expect = 9e-29
 Identities = 81/223 (36%), Positives = 127/223 (56%), Gaps = 7/223 (3%)

Query: 5   QAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLI 64
           +AK+ AA +AV+ FV +  I G+G+GST+ Y ++ L +R ++  LK+T I +S ++ +  
Sbjct: 11  KAKKAAALKAVE-FVQDQMIIGLGTGSTIAYFIEALGKRCQAG-LKITAIASSERSMRQA 68

Query: 65  IKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYT 124
              G+ + + +T   +D+TIDGADE+D    +IKGGGG LL+EK+IAS SK++IV+ D T
Sbjct: 69  RLVGIPIVDSDTILELDLTIDGADEIDPLKQMIKGGGGALLREKLIASASKEMIVVIDET 128

Query: 125 KDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFILD 184
           K   KLG ++     I +    ++  K K    Y G +++           TDNGN+I D
Sbjct: 129 KLVNKLG-KFPVATEISIFTFRHIVKKLKDHG-YCGSLRVNQ---DQSLYRTDNGNYIFD 183

Query: 185 WMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEG 227
             F     +    +N +K   GV+ETGLF N+  +   G   G
Sbjct: 184 ICFPEPIDNPIFEHNRLKSFAGVLETGLFFNLAGRVIIGYQNG 226


>UniRef50_A1CTV2 Cluster: Ribose 5-phosphate isomerase A; n=4;
           Eurotiomycetidae|Rep: Ribose 5-phosphate isomerase A -
           Aspergillus clavatus
          Length = 272

 Score =  128 bits (309), Expect = 1e-28
 Identities = 93/270 (34%), Positives = 139/270 (51%), Gaps = 40/270 (14%)

Query: 3   LEQAKQVAAYQAV-DQFVTNNCIFGVGSGSTVVYAVQRLAER-VESEKLKVTCIPTSFQA 60
           +E AK+ A   AV + + TN    G+GSGST+VY V+ + E  +++ + K   +PT FQ+
Sbjct: 5   IEAAKRAAGQAAVANHYPTNPKFVGIGSGSTIVYVVEAIKESGIDTSQTKY--VPTGFQS 62

Query: 61  KQLIIKHGLNLGELETNPN---IDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKL 117
           KQLI+  GL   E ++ P    +DV  DGADEVD  + LIKGGG CL QEKI+A  +K+ 
Sbjct: 63  KQLILSAGLTAVEFDSLPEGTVLDVAFDGADEVDDELNLIKGGGACLFQEKIVALQAKEF 122

Query: 118 IVIADYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTD 177
           I +AD  K   +L   +K  +PIEV P+A   +  K+  L   +  +R +    GP+ TD
Sbjct: 123 ICVADSRKLQSRLLTNWKY-IPIEVAPIAAPRVLTKLRELGSIQPAIRLSGTSKGPLKTD 181

Query: 178 NGNFILDWMF---------------ANQNLDWE--KVNNTIKLIPGVVETGLFVNMC--- 217
              +++D  F               + +   WE   +   IK+I GV+E G+F  +    
Sbjct: 182 QDFYLIDAPFPPLLTKADVAAGKDGSGKAGVWEANALAQAIKMIAGVLEVGIFSGVTGPQ 241

Query: 218 ------------CKAYFGQPEGNVVERSVI 235
                         AYFG P+G+V  R  +
Sbjct: 242 AQALGGIGGQKPIAAYFGMPDGSVSVRKAL 271


>UniRef50_Q8ZGJ9 Cluster: Ribose-5-phosphate isomerase A 2; n=9;
           Yersinia|Rep: Ribose-5-phosphate isomerase A 2 -
           Yersinia pestis
          Length = 236

 Score =  127 bits (307), Expect = 2e-28
 Identities = 78/227 (34%), Positives = 120/227 (52%), Gaps = 8/227 (3%)

Query: 6   AKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLII 65
           AK+ AA + +  FV +    G+GSG+T  + V+ L + V ++ L++TC  TS    ++  
Sbjct: 8   AKRAAARRVIQDFVFDGMTLGLGSGTTSHFFVRELGQHV-AKGLQLTCTTTSRATSEVAR 66

Query: 66  KHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTK 125
             G+ L +      ID+TIDG DE+D    +IKGGG CLL EKIIA  SK++I I D TK
Sbjct: 67  DVGIELSDPNEMNEIDLTIDGPDEIDRRFNMIKGGGACLLWEKIIAHASKRMICICDETK 126

Query: 126 DSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGE----IKLRSAVAKAGPVVTDNGNF 181
               LG   +  +P+E++P A+   + ++  +   +    + +   +    PV+TD+GNF
Sbjct: 127 IVNCLG---QFPLPVEIVPFAWKQTERRVERVLAEQGLHHVPIIRRMGGGHPVITDSGNF 183

Query: 182 ILDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGN 228
           ILD          E +   +  IPGVVE GLF         G  +G+
Sbjct: 184 ILDCHCGAIITAPEPLEIELNRIPGVVENGLFTREATGMVVGYFDGS 230


>UniRef50_Q8A699 Cluster: Putative ribose 5-phosphate isomerase;
           n=4; Bacteroides|Rep: Putative ribose 5-phosphate
           isomerase - Bacteroides thetaiotaomicron
          Length = 233

 Score =  127 bits (306), Expect = 3e-28
 Identities = 80/211 (37%), Positives = 116/211 (54%), Gaps = 7/211 (3%)

Query: 5   QAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLI 64
           +AK+  A +      T + I G GSGSTV   +  LA+R+  E L +  IP S +     
Sbjct: 21  EAKERVAREIAATAKTGDVI-GAGSGSTVYLTLFELAKRIHEEHLYLEVIPASQEISMTC 79

Query: 65  IKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYT 124
           I+ G+    L  +   D T DGADEVD +  LIKG GG + +EK++   S K  +I D +
Sbjct: 80  IQLGIPQTTL-WDKRPDWTFDGADEVDPDRNLIKGRGGAMFKEKLLIRSSGKTFIIVDPS 138

Query: 125 KDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFILD 184
           K    LG ++   +P+EV P A   ++ ++  L   EI LR A  K GP++T+NGNFILD
Sbjct: 139 KLVNILGSKFP--IPVEVFPHALSYVEKELRRLGASEISLRPAHGKDGPILTENGNFILD 196

Query: 185 WMFANQNLDWEKVNNTIKLIPGVVETGLFVN 215
             F    +D   +   +K I GV+E+GLF+N
Sbjct: 197 TRF--HYID-ASLEEQLKTITGVIESGLFIN 224


>UniRef50_O51601 Cluster: Ribose-5-phosphate isomerase A; n=3;
           Borrelia burgdorferi group|Rep: Ribose-5-phosphate
           isomerase A - Borrelia burgdorferi (Lyme disease
           spirochete)
          Length = 228

 Score =  127 bits (306), Expect = 3e-28
 Identities = 83/217 (38%), Positives = 121/217 (55%), Gaps = 13/217 (5%)

Query: 3   LEQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLK-VTCIPTSFQAK 61
           +E  K + A  A+D ++ +N   G+G+G+T+ YA++ L+E+++S  LK +    TS   K
Sbjct: 1   MENQKILVAKHAIDHYIKSNMNLGIGTGTTIYYAIKYLSEKIKSGSLKNLKFYTTSSDTK 60

Query: 62  QLIIKHGL----NLGELETNPNIDVTIDGADEV-DSNMTLIKGGGGCLLQEKIIASCSKK 116
            L+ K  +    N  +L  N N+D+ IDGADE+     +LIKG GG  L EK+IA  S+ 
Sbjct: 61  YLLSKEQIPYESNFSKL--NKNLDIAIDGADEILLEKKSLIKGMGGAHLMEKVIAYNSET 118

Query: 117 LIVIADYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVT 176
           L++IAD TK   KLG   K  +PIEV   A   I  ++  +   E  LR    K GP +T
Sbjct: 119 LLIIADETKIVKKLGT--KMPIPIEVAQNAVGFIMTRLEEM-NLEATLRICKEKKGPTIT 175

Query: 177 DNGNFILDWMFANQNLDWEKVNNTIKLIPGVVETGLF 213
           DN N+ILD     +N   E      KL PG++E G+F
Sbjct: 176 DNNNYILDVKMHVENP--EGTEKYFKLFPGILEIGIF 210


>UniRef50_A3DN78 Cluster: Ribose 5-phosphate isomerase; n=1;
           Staphylothermus marinus F1|Rep: Ribose 5-phosphate
           isomerase - Staphylothermus marinus (strain ATCC 43588 /
           DSM 3639 / F1)
          Length = 233

 Score =  126 bits (305), Expect = 4e-28
 Identities = 84/232 (36%), Positives = 129/232 (55%), Gaps = 10/232 (4%)

Query: 4   EQAKQVAAYQAVDQFVT---NNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQA 60
           E  K++++  A+  F+    ++ + G+G+GSTV Y +  L      +  KV  + +S+  
Sbjct: 3   EYLKKLSSIYALRMFIDKIRDSKVLGIGTGSTVKYFIDELIRLGMLKDKKV--VVSSYAT 60

Query: 61  KQLIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVI 120
              + KHG++          D+ +DG DE+++N+ +IKG G  LL EK +A  SK  I I
Sbjct: 61  HNYLYKHGIDAYTPINCNYADIYVDGLDEINANLDIIKGRGAALLWEKQLAIRSKLRIYI 120

Query: 121 ADYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGN 180
           ADYTK + +    Y K VPIEV+P A   +  K +++ G +  LR    K GP++TDNGN
Sbjct: 121 ADYTKVNPE-QYLYMKPVPIEVVPNAVYYVIEK-LTILGYKPVLRIGKMKDGPIITDNGN 178

Query: 181 FILDWMFAN-QNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGNVVE 231
           FI+D ++   QN   ++V+  IK I GVVETGLF N           GN+V+
Sbjct: 179 FIIDLVYEKIQNA--KQVDEEIKKINGVVETGLFPNNLVDYVIVSYPGNIVK 228


>UniRef50_Q9HJT5 Cluster: Ribose-5-phosphate isomerase A; n=2;
           Thermoplasma|Rep: Ribose-5-phosphate isomerase A -
           Thermoplasma acidophilum
          Length = 241

 Score =  126 bits (305), Expect = 4e-28
 Identities = 81/224 (36%), Positives = 124/224 (55%), Gaps = 7/224 (3%)

Query: 4   EQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQL 63
           E+ K  AA +A + +V +  I G+G+G+T  Y +  +  RV  E LK+  + TS + + L
Sbjct: 5   EKQKMNAAIKAAE-YVRSGMIVGLGTGTTSYYLINEIGRRVREEGLKIRAVCTSRRTEDL 63

Query: 64  IIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADY 123
             ++G+ + +  T   ID+TIDGAD+V    TLIKGGGG LL+EKI+A  SK++ VI D 
Sbjct: 64  AKQNGIEVIQ-GTKDQIDLTIDGADQVGMYGTLIKGGGGALLREKIVAYNSKEMYVIVDS 122

Query: 124 TKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFIL 183
            K  ++        +P+E++P  ++     +  +   +  LR    K  P VTDNGN+I 
Sbjct: 123 RK--IEAAHFGSFPLPVEIVPFMHMRTLENLRGIC-TQTDLRMN-EKGEPFVTDNGNYIA 178

Query: 184 DWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEG 227
           D M      D   +  ++K IPGVVE GLF  +  + + G  EG
Sbjct: 179 D-MHMGMIDDPINLERSLKSIPGVVEVGLFNGIAKRIFEGTDEG 221


>UniRef50_Q139E9 Cluster: Ribose 5-phosphate isomerase; n=2;
           Alphaproteobacteria|Rep: Ribose 5-phosphate isomerase -
           Rhodopseudomonas palustris (strain BisB5)
          Length = 232

 Score =  126 bits (304), Expect = 5e-28
 Identities = 88/239 (36%), Positives = 131/239 (54%), Gaps = 13/239 (5%)

Query: 1   MSLEQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQA 60
           M  E  K+ AA +A+++ V +    G+G+GST  + V+ L E+V    L V  +PTS   
Sbjct: 1   MDKEDLKRQAAARALEE-VRSGMKLGLGTGSTARHFVELLGEKVRGG-LDVIGVPTSEVT 58

Query: 61  KQLIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVI 120
           +    + G+ L  L+    +D+T+DGADEVD+ + LIKGGGG LL+EKI+A+ S ++IVI
Sbjct: 59  RADAERCGIRLTTLDEIDRLDLTVDGADEVDTRLELIKGGGGALLREKIVAAASDRMIVI 118

Query: 121 ADYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLY-----GGEIKLRSAVAKAGPVV 175
           AD +K    LG   K  +P+EVIP      +  I   +      G++KLR   A     V
Sbjct: 119 ADESKWVDCLG---KFPLPVEVIPFGLAATRRAIEKAFTQVGAAGQLKLRDGEA-GHAFV 174

Query: 176 TDNGNFILDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEG-NVVERS 233
           TD G++I+D     +  D  ++   +  IPGVVE GLF+ +         EG   VER+
Sbjct: 175 TDGGHWIVD-AHLGRIPDAPRLAKLLSEIPGVVEHGLFIGIASTVVLAGTEGIRTVERA 232


>UniRef50_Q1ERB6 Cluster: Ribose 5-phosphate isomerase; n=1;
           uncultured crenarchaeote 31-F-01|Rep: Ribose 5-phosphate
           isomerase - uncultured crenarchaeote 31-F-01
          Length = 230

 Score =  126 bits (304), Expect = 5e-28
 Identities = 76/218 (34%), Positives = 124/218 (56%), Gaps = 11/218 (5%)

Query: 14  AVDQFVTNNCIFGVGSGSTVVYAVQRLAERVES---EKLKVTCIPTSFQAKQLIIKHGLN 70
           AV + V +  I G+GSG TV   +  LA    S   +   +  IPTS Q K    +  ++
Sbjct: 13  AVYEHVRDGMIIGLGSGRTVAALLDVLARMSRSMGIDMASIRFIPTSLQIKMKAEELKMS 72

Query: 71  LGELETNPNIDVTIDGADEVDSN-MTLIKGGGGCLLQEKIIASCSKKLIVIADYTKDSVK 129
           +G+    P++D+  DGAD++D+N + +IKGGGG LL+EK++   +KK++++AD +    K
Sbjct: 73  IGDESLIPSVDLVFDGADQIDANSLVMIKGGGGALLREKVLMYAAKKVVILADES----K 128

Query: 130 LGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFILDWMFAN 189
             D+    +PIEV+P A   + N + S+Y  E  +R    +  P++T+NGN I+D +F++
Sbjct: 129 YVDKLTLPIPIEVVPYARAYVSNMLRSMY-AEPSVR-VNDRGYPIMTENGNIIIDTVFSS 186

Query: 190 QNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEG 227
              D   + + +K IPGVVE GLF       Y  + +G
Sbjct: 187 IE-DPYNLEHRLKCIPGVVEVGLFSKAADLYYKARGDG 223


>UniRef50_Q6L1K2 Cluster: Ribose-5-phosphate isomerase A; n=2;
           Thermoplasmatales|Rep: Ribose-5-phosphate isomerase A -
           Picrophilus torridus
          Length = 218

 Score =  125 bits (302), Expect = 9e-28
 Identities = 82/225 (36%), Positives = 137/225 (60%), Gaps = 17/225 (7%)

Query: 4   EQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQL 63
           E  K++AA +A+ +FV N+   G+G+GST  Y ++ L+E V++  L++T IPTS ++++L
Sbjct: 3   ENEKRMAAMEAL-KFVRNDMRIGIGTGSTAYYFIEGLSELVKNG-LRITGIPTSKKSEEL 60

Query: 64  IIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADY 123
                 N+       +ID+  DGADE D    LIKGGGG L++EKI+A  S++  V+ D+
Sbjct: 61  C--RSFNIPVDYNIKDIDIDFDGADEFDPYGNLIKGGGGALVREKIVAYNSREFYVLVDH 118

Query: 124 TKDSVKLGDRYKKGVPIEVIP-MAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFI 182
           +K S +L   +K  +P+EV+P M+   ++N  I   G     R++       ++DNGN+I
Sbjct: 119 SKYSERL---HKFPLPVEVLPFMSEKTLEN--IERLG----CRASFRDDKKFISDNGNYI 169

Query: 183 LDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEG 227
           +D +F+  + + E   + IK+IPGVVE G+F ++  K + G  +G
Sbjct: 170 IDCVFSYTDPELE---SQIKMIPGVVEVGIFRHLSTKIFQGTIDG 211


>UniRef50_Q0UHN5 Cluster: Putative uncharacterized protein; n=3;
           Pezizomycotina|Rep: Putative uncharacterized protein -
           Phaeosphaeria nodorum (Septoria nodorum)
          Length = 284

 Score =  125 bits (301), Expect = 1e-27
 Identities = 73/191 (38%), Positives = 113/191 (59%), Gaps = 8/191 (4%)

Query: 2   SLEQAKQVAAYQAV-DQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQA 60
           ++E AK+ AA QAV D F  ++   G+GSG+T+VY V+ + ER  S    +  +PT +Q+
Sbjct: 5   AVEAAKRAAAQQAVKDHFDPSSTHVGIGSGTTIVYVVEAIKER--STNPNILFVPTGYQS 62

Query: 61  KQLIIKHGLNLGELETNPN---IDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKL 117
           +QL+I  GL     ++ P+   +DV  DGADEVD+ +  IKGGG CL QEK++A  +KK 
Sbjct: 63  RQLVINAGLTPISFDSLPDHIMLDVAFDGADEVDAELNCIKGGGACLFQEKLVAERAKKF 122

Query: 118 IVIADYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSA-VAKAGPVVT 176
           + +ADY K   +L   +   +PIEV P++   +   +  L      LR+  + K+GP+ T
Sbjct: 123 VCVADYRKRQDRLLTIWPT-IPIEVAPLSQRKVVAALKLLGSPNPTLRTTLLEKSGPLKT 181

Query: 177 DNGNFILDWMF 187
           D   +I+D  F
Sbjct: 182 DQDFYIVDAPF 192


>UniRef50_A5ABI2 Cluster: Catalytic activity: RPIs catalyse the
           reaction; n=3; Pezizomycotina|Rep: Catalytic activity:
           RPIs catalyse the reaction - Aspergillus niger
          Length = 273

 Score =  124 bits (300), Expect = 1e-27
 Identities = 94/268 (35%), Positives = 139/268 (51%), Gaps = 41/268 (15%)

Query: 3   LEQAKQVAAYQAVDQFVTNNCIF-GVGSGSTVVYAVQRLAER-VESEKLKVTCIPTSFQA 60
           +E AK+ A   AV+     +  + G+GSGST+VY V+ + E  V++   K   +PT FQ+
Sbjct: 5   VEAAKRAAGKAAVENHYPKDAKYVGIGSGSTIVYVVEAIKESGVDTSATKY--VPTGFQS 62

Query: 61  KQLIIKHGLNLGELETNPN---IDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKL 117
           KQLI+  GL   + +  P    +DV  DGADEVD  + LIKGGG CL QEKI+A  +K+ 
Sbjct: 63  KQLIVNAGLTAVDFDALPEGTVLDVAFDGADEVDDELNLIKGGGACLFQEKIVALQAKEF 122

Query: 118 IVIADYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLR-SAVAKAGPVVT 176
           I +AD  K   +L   +K  +PIEV P+A   +   +  +   +  +R ++ AK GP+ T
Sbjct: 123 ICVADSRKLQSRLLTGWKY-IPIEVAPIAARRVLGALKEIGSIDPAVRVNSDAKQGPLKT 181

Query: 177 DNGNFILDWMF---------------ANQNLDWE--KVNNTIKLIPGVVETGLFVNMC-- 217
           D   FI+D  F               + ++  WE   ++  IK IPGV++ G+F  M   
Sbjct: 182 DQAFFIIDAPFKTLLTQADVAAGKDGSGKDGVWEVHALSQAIKQIPGVLDVGIFSGMTGP 241

Query: 218 -------------CKAYFGQPEGNVVER 232
                          AYFG P+G+V  R
Sbjct: 242 QAQALGGVGGQKPIAAYFGMPDGSVSVR 269


>UniRef50_A1RX06 Cluster: Ribose 5-phosphate isomerase; n=1;
           Thermofilum pendens Hrk 5|Rep: Ribose 5-phosphate
           isomerase - Thermofilum pendens (strain Hrk 5)
          Length = 223

 Score =  124 bits (299), Expect = 2e-27
 Identities = 83/207 (40%), Positives = 120/207 (57%), Gaps = 10/207 (4%)

Query: 10  AAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIKHGL 69
           AA +A  + V +  + G+GSG+TV   +  LAERV  E L +  + +S          GL
Sbjct: 5   AAREAA-RHVRDGMVVGLGSGTTVKIFIDVLAERVRQENLTIFFVSSSIDTSLYAAGKGL 63

Query: 70  NLGEL-ETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTKDSV 128
               L E  P  +V+ DGAD V  + +LIKGGGGCLL+EKI+   SK+ +VI D TK  V
Sbjct: 64  LEVPLHEYTP--EVSFDGADTVLPDRSLIKGGGGCLLREKIVDYYSKEYVVIVDATK--V 119

Query: 129 KLGDRYKKGVPIEVIPMAYVPIKNKIISLYGG-EIKLRS-AVAKAGPVVTDNGNFILDWM 186
               R    VP+EV P A+  +  ++   YG   + LR+    K GPV+TDNGNFILD +
Sbjct: 120 AETPR-NLNVPVEVHPQAFKKVMEELRKSYGAVNVTLRTYEKGKLGPVLTDNGNFILDAL 178

Query: 187 FANQNLDWEKVNNTIKLIPGVVETGLF 213
           F ++  D  ++  ++K +PG++ETG+F
Sbjct: 179 F-DELKDPLRLELSLKSVPGLIETGIF 204


>UniRef50_Q1H2B3 Cluster: Ribose 5-phosphate isomerase; n=1;
           Methylobacillus flagellatus KT|Rep: Ribose 5-phosphate
           isomerase - Methylobacillus flagellatus (strain KT /
           ATCC 51484 / DSM 6875)
          Length = 230

 Score =  124 bits (298), Expect = 3e-27
 Identities = 78/225 (34%), Positives = 125/225 (55%), Gaps = 6/225 (2%)

Query: 7   KQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIK 66
           KQ+ A QA  Q V +  + G+G+GST  Y ++ LA R   E L +T   +S  +      
Sbjct: 4   KQLVAIQAA-QHVQDGMVVGLGTGSTANYFIEELARRHRDEGLHITAAASSVASTIQAQT 62

Query: 67  HGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTKD 126
           HGL L  LE    +D+ +DGADEV +N+ L+KG G  L++EK++A  S++ IV+ D +K 
Sbjct: 63  HGLPLVALEHLGRLDLYVDGADEVTTNLALLKGRGYDLVREKLLARASERFIVLVDKSKL 122

Query: 127 SVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFILDWM 186
              LG+++   +P+EVIP A+  ++  +  L G    LR   AK G  +T +G+ +L+ +
Sbjct: 123 VGHLGEKFP--IPLEVIPFAWQLVQASLQQL-GIASSLRQNAAKDGWAITSHGSLVLE-L 178

Query: 187 FANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGNVVE 231
              +    +++N  +  IPG+VE G+F  +   A F    G V E
Sbjct: 179 TLPKTFKSDELNRLLNDIPGIVEHGVFDEL-ADAVFVADNGQVEE 222


>UniRef50_Q11IC0 Cluster: Ribose 5-phosphate isomerase; n=4;
           Bacteria|Rep: Ribose 5-phosphate isomerase -
           Mesorhizobium sp. (strain BNC1)
          Length = 235

 Score =  124 bits (298), Expect = 3e-27
 Identities = 80/213 (37%), Positives = 117/213 (54%), Gaps = 8/213 (3%)

Query: 18  FVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIKHGLNLGELETN 77
           +V +    G+G+GST    V+ LA RV S  +K+  +PTS +   L  +  + L  L+  
Sbjct: 18  YVEDGMKLGIGTGSTAEEFVRLLATRVSSG-MKIVGVPTSERTAALCRELSVPLSTLDET 76

Query: 78  PNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTKDSVKLGDRYKKG 137
           P +D+T+DGADEV  ++TLIKGGGG LL+EKI+A+ S+++IVIAD +K    LG      
Sbjct: 77  PELDLTVDGADEVGPDLTLIKGGGGALLREKIVAAASRRMIVIADESKVVDVLG---TFP 133

Query: 138 VPIEVIPMAYVPIKNKI---ISLYGGEIKLRSAVAKAGPVVTDNGNFILDWMFANQNLDW 194
           +PIEV P      +  I    +  G   ++R+ +A   P VTD G+FI+D  F       
Sbjct: 134 LPIEVNPFGLRATRIAIEAAAARLGLAGEMRTRMAGQEPFVTDGGHFIIDASFGRIQAP- 192

Query: 195 EKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEG 227
             +   +  IPGVVE GLF+ +   A      G
Sbjct: 193 RALAEALNAIPGVVEHGLFIGLAGAAIIAGRNG 225


>UniRef50_Q8YH30 Cluster: Ribose-5-phosphate isomerase A; n=32;
           Bacteria|Rep: Ribose-5-phosphate isomerase A - Brucella
           melitensis
          Length = 232

 Score =  122 bits (295), Expect = 6e-27
 Identities = 83/225 (36%), Positives = 128/225 (56%), Gaps = 12/225 (5%)

Query: 8   QVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIKH 67
           ++AA      +V +    G+G+GST    V+ LAE+V+    +V  +PTS +  +L  + 
Sbjct: 8   KIAAAAEALTYVKDGMRLGIGTGSTAEEFVRLLAEKVKGG-FRVIGVPTSERTAKLCEEL 66

Query: 68  GLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTKDS 127
           G+ L  LE  P++D+TIDGADEVD  ++LIKGGGG LL+EKI+A+ S  +IVIAD +K  
Sbjct: 67  GVALTTLEETPHLDLTIDGADEVDGELSLIKGGGGALLREKIVAAASDSMIVIADQSKVV 126

Query: 128 VKLGDRYKKGVPIEV----IPMAYVPIKNKIISL-YGGEIKLRSAVAKAGPVVTDNGNFI 182
             LG R+   +PIEV    +      I+   +     G + LR  +    P +TD G++I
Sbjct: 127 ETLG-RFP--LPIEVNRFGLGATIRAIEAAAVKCGLAGPLNLR--LKDGSPFLTDGGHYI 181

Query: 183 LDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEG 227
           +D  F  +  D + +++ +  IPGVVE GLF+ +   A     +G
Sbjct: 182 VDASF-GRIPDPKTLSDALFAIPGVVEHGLFIELARAAIIAGTDG 225


>UniRef50_Q01M03 Cluster: OSIGBa0096F13.7 protein; n=4; Oryza
           sativa|Rep: OSIGBa0096F13.7 protein - Oryza sativa
           (Rice)
          Length = 275

 Score =  122 bits (294), Expect = 8e-27
 Identities = 81/237 (34%), Positives = 130/237 (54%), Gaps = 14/237 (5%)

Query: 4   EQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLK-VTCIPTSFQAKQ 62
           E+ K+VAA++AV+  V      G+G+GST  +A+ RL + + S +L  V  +PTS + + 
Sbjct: 35  EELKRVAAHRAVEM-VEPGMTLGLGTGSTAAHALDRLGDLLRSGELAAVAGVPTSLKTEA 93

Query: 63  LIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIAD 122
              + G+ +  L     ID++IDGADEVD  + L+KG GG LL+EK+I     + +VI D
Sbjct: 94  HAARVGIPMLPLGEAGGIDLSIDGADEVDPELNLVKGRGGSLLREKMIEGSGGRFVVIVD 153

Query: 123 YTKDSVKLGDRYKKGVPIEVIPMA---YVPIKNKII-SLYGGEIKLRSAVAKAGP----- 173
            +K   +LG      VP+EV+P      + +  K+   L G   +LR+  +K G      
Sbjct: 154 ESKLVPRLG--CTGAVPVEVVPFGCDHTLGLVRKVFDGLPGFSARLRTVASKDGEGKEEM 211

Query: 174 VVTDNGNFILDWMFANQ-NLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGNV 229
            VTDNGN+I++  F +    D  ++++ +  I GVVE G+F+ M       + +G V
Sbjct: 212 FVTDNGNYIVEMFFEDGIRGDLNEISDRLLRITGVVEHGMFLGMATSVVVAKKDGTV 268


>UniRef50_Q8G3X9 Cluster: Ribose-5-phosphate isomerase A; n=14;
           Bacteria|Rep: Ribose-5-phosphate isomerase A -
           Bifidobacterium longum
          Length = 232

 Score =  122 bits (293), Expect = 1e-26
 Identities = 82/221 (37%), Positives = 117/221 (52%), Gaps = 7/221 (3%)

Query: 7   KQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIK 66
           K+ A  +A  + V N  I G+G+GSTV + V  L  R + E L+ T + TS + +     
Sbjct: 10  KKAAGIEAA-KLVENGMIAGLGTGSTVKFLVDELGRRHQEEGLEFTGVTTSRRTQAQAES 68

Query: 67  HGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTKD 126
           +G+ + +++   +IDVTIDGADEVD N   IKGGG  LL EKI+A+ S +++ I D +K 
Sbjct: 69  YGIKIVDIDDVDHIDVTIDGADEVDKNFNGIKGGGAALLWEKIVATNSNQIVWIVDESKV 128

Query: 127 SVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFILDWM 186
              +G   K  +P+EVIP     +  K     G +  LR   A    V TD  NF++D  
Sbjct: 129 VDTIG---KFPLPVEVIPFGAGQVIKK-FEARGYKPVLR-LDADGKEVRTDENNFVVDLH 183

Query: 187 FANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEG 227
               +   E   + I  + GVVE GLF+NM  K   G P G
Sbjct: 184 LERIDHPQELAEDLINTV-GVVEHGLFLNMVDKVIVGDPNG 223


>UniRef50_A6LVZ7 Cluster: Ribose 5-phosphate isomerase; n=1;
           Clostridium beijerinckii NCIMB 8052|Rep: Ribose
           5-phosphate isomerase - Clostridium beijerinckii NCIMB
           8052
          Length = 233

 Score =  121 bits (292), Expect = 1e-26
 Identities = 71/221 (32%), Positives = 124/221 (56%), Gaps = 9/221 (4%)

Query: 7   KQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIK 66
           K+VA  ++ + ++ +  I G+G+GST  Y ++++ E +++  +K+  + TS   + L  +
Sbjct: 4   KRVAGEKSTE-YIKDGMILGLGTGSTAYYMIKKVGELIKNG-MKIKAVATSKSTESLARE 61

Query: 67  HGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTKD 126
             + L  ++    ID+ IDG DE+D+    IKGGGG L +EKI+AS + ++I I D +K 
Sbjct: 62  LKIPLLSIDEVDRIDLAIDGVDEIDNEFNAIKGGGGALFREKIVASLANEVIWIMDESKL 121

Query: 127 SVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFILDWM 186
              +G+     +P+E++P  Y   K+ I  L    +  +  + +    VTDNGN+I+D +
Sbjct: 122 VDGIGE---FPLPVEILPYGY---KHVIKELQDYSLNPKIRMKEEEIFVTDNGNYIVD-L 174

Query: 187 FANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEG 227
                ++   V N +  I GV+ETGLF+NMC +   G   G
Sbjct: 175 HIGTPMNINDVYNKVNRITGVLETGLFINMCNRIIIGTNSG 215


>UniRef50_Q5HLQ9 Cluster: Ribose-5-phosphate isomerase A; n=16;
           Staphylococcus|Rep: Ribose-5-phosphate isomerase A -
           Staphylococcus epidermidis (strain ATCC 35984 / RP62A)
          Length = 230

 Score =  121 bits (291), Expect = 2e-26
 Identities = 68/209 (32%), Positives = 117/209 (55%), Gaps = 5/209 (2%)

Query: 19  VTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIKHGLNLGELETNP 78
           + N    G+G+GST+   + ++AE ++ +   +T + TS +   L  +  +N+ ++    
Sbjct: 19  IENGMTIGIGTGSTIELLIPQIAELIQQKNYTITGVCTSNKTAFLAKELAMNIVDVNDVE 78

Query: 79  NIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTKDSVKLGDRYKKGV 138
            ID+ IDGADEVDS + LIKGGGG L +EK+I   + + +V+ D +K    LG+ +   +
Sbjct: 79  KIDLAIDGADEVDSALNLIKGGGGALFREKVIDEMADRFVVVVDESKLVNYLGETF--AL 136

Query: 139 PIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFILDWMFANQNLDWEKVN 198
           P+EV    +  +  KI   Y  +I +   V +  P +TDNGN+ILD    N+   +E ++
Sbjct: 137 PVEVDKFNWYQVAKKIERTY--DIHVSRRVNEDVPFITDNGNYILDCSLQNRIPAYE-LH 193

Query: 199 NTIKLIPGVVETGLFVNMCCKAYFGQPEG 227
             +  + GV+ETG F+++  +   G  EG
Sbjct: 194 EFLIHLTGVLETGYFLDIADQVIVGTQEG 222


>UniRef50_P0A7Z3 Cluster: Ribose-5-phosphate isomerase A; n=115;
           Proteobacteria|Rep: Ribose-5-phosphate isomerase A -
           Shigella flexneri
          Length = 219

 Score =  120 bits (288), Expect = 4e-26
 Identities = 83/228 (36%), Positives = 124/228 (54%), Gaps = 16/228 (7%)

Query: 1   MSLEQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQA 60
           M+ ++ K+   + A+ Q+V    I GVG+GST  + +  L       +  V+    S + 
Sbjct: 1   MTQDELKKAVGWAAL-QYVQPGTIVGVGTGSTAAHFIDALGTMKGQIEGAVSSSDASTEK 59

Query: 61  KQLIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVI 120
            + +  H  +L E+++   + + +DGADE++ +M +IKGGG  L +EKIIAS ++K I I
Sbjct: 60  LKSLGIHVFDLNEVDS---LGIYVDGADEINGHMQMIKGGGAALTREKIIASVAEKFICI 116

Query: 121 ADYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGN 180
           AD +K    LG   K  +P+EVIPMA   +  +++ L GG  + R        VVTDNGN
Sbjct: 117 ADASKQVDILG---KFPLPVEVIPMARSAVARQLVKL-GGRPEYRQG------VVTDNGN 166

Query: 181 FILDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCK-AYFGQPEG 227
            ILD +   + LD   + N I  IPGVV  GLF N     A  G P+G
Sbjct: 167 VILD-VHGMEILDPIAMENAINAIPGVVTVGLFANRGADVALIGTPDG 213


>UniRef50_P57961 Cluster: Ribose-5-phosphate isomerase A; n=28;
           Proteobacteria|Rep: Ribose-5-phosphate isomerase A -
           Pasteurella multocida
          Length = 219

 Score =  120 bits (288), Expect = 4e-26
 Identities = 87/233 (37%), Positives = 124/233 (53%), Gaps = 21/233 (9%)

Query: 3   LEQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQ 62
           LE  K  AA  A  Q+V  + I GVGSGSTV   ++ L    +  K     +  S  ++ 
Sbjct: 4   LEMKKMAAA--AALQYVKPDSIIGVGSGSTVNCFIEALGSMRDQIK---GAVAASKASEA 58

Query: 63  LIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIAD 122
           L+ K G+ +       ++D+ +DGADE++    +IKGGG  L +EKI+A+ +KK I I D
Sbjct: 59  LLAKQGIEVFSANEVSSLDIYVDGADEINPQKMMIKGGGAALTREKIVAALAKKFICIVD 118

Query: 123 YTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFI 182
            +K    LG  +   +P+EVIPMA   +  K+++L GG  + R        VVTDNGN I
Sbjct: 119 TSKQVDVLGSTF--ALPVEVIPMARSQVARKLVAL-GGSPEYREG------VVTDNGNVI 169

Query: 183 LD-WMFANQN-LDWEKVNNTIKLIPGVVETGLFVNMCCKAYF-GQPEG-NVVE 231
           LD + FA  N ++ EK  N    +PGVV  G+F          G PEG  V+E
Sbjct: 170 LDVYHFAIMNPVEMEKELNN---VPGVVTNGIFALRAADIIIVGTPEGAKVIE 219


>UniRef50_Q92D46 Cluster: Ribose-5-phosphate isomerase A; n=13;
           Listeria|Rep: Ribose-5-phosphate isomerase A - Listeria
           innocua
          Length = 224

 Score =  118 bits (284), Expect = 1e-25
 Identities = 81/225 (36%), Positives = 126/225 (56%), Gaps = 12/225 (5%)

Query: 7   KQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIK 66
           K++A  +A + ++ +  + G+G+GSTV Y +++L E V+ + L +T + TS + +Q    
Sbjct: 5   KKIAGEKACE-WIEDGMVVGLGTGSTVYYTIEKLGEMVQ-KGLNITGVSTSIETEQQART 62

Query: 67  HGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTKD 126
            G+ L  L     IDVTIDGADE++     IKGGGG LL+EK++A  S K I +    K 
Sbjct: 63  LGIPLKSLNDVTKIDVTIDGADEINQAFQGIKGGGGALLREKMVAQASSKNIWVVGEEKL 122

Query: 127 SVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVV-TDNGNFILDW 185
             +LG   K  +P+EVIP  +  IK +++   G E  LR     +G +  T+NGN+ILD 
Sbjct: 123 VTELG---KFPLPLEVIPFGWKQIK-RMLENDGVETTLRK--QSSGEIYETNNGNYILD- 175

Query: 186 MFANQNL-DWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGNV 229
              NQ   + E  +  +  IPGV+E GLF++       G+  G +
Sbjct: 176 -IINQTFTNPEAWHEKLAGIPGVLEHGLFLHYVDIIICGKASGEI 219


>UniRef50_Q8ZXY8 Cluster: Ribose 5-phosphate isomerase; n=5;
           Thermoproteaceae|Rep: Ribose 5-phosphate isomerase -
           Pyrobaculum aerophilum
          Length = 223

 Score =  116 bits (280), Expect = 4e-25
 Identities = 75/209 (35%), Positives = 118/209 (56%), Gaps = 10/209 (4%)

Query: 7   KQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIK 66
           K++ A +A+ + V +  + G+GSG+T    ++ LAE    + L V    TS  ++ L  +
Sbjct: 3   KRLLAREAI-RLVKSGMVVGLGSGTTAREFIKALAEAGVDDVLLVA---TSSDSEILAYE 58

Query: 67  HGLN--LGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYT 124
            GL   L  +     ID+ +DGADEV  +  L+KG GG LL+EKI+   ++K +V+ +  
Sbjct: 59  VGLGDRLRPMWAVDRIDLAVDGADEVTKDKVLLKGKGGALLREKIVDYAAEKFVVLIEEH 118

Query: 125 KDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFILD 184
           K   ++       VP+EV+P A+  +  ++   +GG  KLR    K GPVVTDNGN+I+D
Sbjct: 119 KLVERIPSN--NPVPVEVVPWAWRFVAREVEKRFGGVAKLRQDGGKLGPVVTDNGNYIID 176

Query: 185 WMFANQNLDWEKVNNTIKLIPGVVETGLF 213
           W      +D   + + +K IPGVVE G+F
Sbjct: 177 WN-PPGFID-PYLEDELKAIPGVVENGVF 203


>UniRef50_Q4MZ63 Cluster: Ribose 5-phosphate epimerase, putative;
           n=2; Theileria|Rep: Ribose 5-phosphate epimerase,
           putative - Theileria parva
          Length = 363

 Score =  116 bits (279), Expect = 5e-25
 Identities = 80/233 (34%), Positives = 134/233 (57%), Gaps = 16/233 (6%)

Query: 8   QVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKL-KVTCIPTS----FQAKQ 62
           ++ A +AVD +V +N I  +G+G T  +A++RLA  ++++ +  +  IPTS     +AK+
Sbjct: 11  KLVAEKAVDTYVKSNSIIALGTGRTSTFALERLANHIKTKSITNILGIPTSQATYLKAKE 70

Query: 63  LIIKHGLNLGE-LETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIA 121
           L I   ++L E + ++  I++ IDGAD VDS++ LIKGGGG L  E ++   S +LI++ 
Sbjct: 71  LEIPL-ISLDEVIGSDRRINIAIDGADSVDSDLNLIKGGGGALFTEFMVEQYSDQLIIMI 129

Query: 122 DYTK--DSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSA-VAKAGPV-VTD 177
           D +K  +   L   Y   +PIE++   ++    +I S +  +I   S  +   G + +TD
Sbjct: 130 DESKLCNDHLLESHY---LPIEIVKGCHLTTCKQIYSKFKSQIVNWSVRMNSDGSLFLTD 186

Query: 178 NGNFILDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGNVV 230
           NGN I+D  F    LD  ++   +KLI GVV +GLF+NM  K    + +  +V
Sbjct: 187 NGNVIMDTQFKQTPLD--QLQKDLKLIHGVVCSGLFLNMATKCLVAKSDNTIV 237


>UniRef50_A0RTM4 Cluster: Ribose 5-phosphate isomerase; n=2;
           Thermoprotei|Rep: Ribose 5-phosphate isomerase -
           Cenarchaeum symbiosum
          Length = 225

 Score =  116 bits (279), Expect = 5e-25
 Identities = 73/226 (32%), Positives = 116/226 (51%), Gaps = 8/226 (3%)

Query: 2   SLEQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAK 61
           +LE A +  +  A++  V +  + G+GSG      V+ LA R  SE++ +T +PTS Q +
Sbjct: 3   ALEDAFRAISADALNM-VKDGQVIGLGSGRAAAVLVRELASRARSERMNITGVPTSLQIR 61

Query: 62  QLIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIA 121
            +  + G++L +      ID+  DGAD+VD    LIKGGGG LL E I+   + K+++IA
Sbjct: 62  LVAEECGISLRDPGDTDKIDIVFDGADQVDRQGNLIKGGGGALLTESILIGMADKVVIIA 121

Query: 122 DYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNF 181
           D +    K  +     VP+EV P A       ++ L GG+  LR  + +  P+ T+N N 
Sbjct: 122 DES----KFAEHLDAPVPVEVHPAARRSAAESVMRL-GGKPVLR-LLDRGFPLFTENRNL 175

Query: 182 ILDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEG 227
           +LD  F     D   + + +  IPGV E G+        Y  + +G
Sbjct: 176 VLDCSFGTIT-DPSTLRDKLTDIPGVAEAGIITRRPDTTYRAKTDG 220


>UniRef50_Q97J55 Cluster: Ribose 5-phosphate isomerase; n=2;
           Clostridium|Rep: Ribose 5-phosphate isomerase -
           Clostridium acetobutylicum
          Length = 227

 Score =  115 bits (277), Expect = 9e-25
 Identities = 67/220 (30%), Positives = 127/220 (57%), Gaps = 6/220 (2%)

Query: 1   MSLEQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQA 60
           M+ +  K+++A +A++ ++ +N + G+G G T+ Y    L E+++S    +  +  S + 
Sbjct: 1   MAKDNLKKISAKKALE-YIKDNTVIGLGGGETIGYLCDYLKEKIKSG-FNIKVVTPSIKT 58

Query: 61  KQLIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVI 120
           +   I++G+ +    +  ++DV  DG D++D  +  +K  GG   +EKIIAS + K I++
Sbjct: 59  RNTCIENGIEVLYTSSVEHLDVAFDGCDQLDEKLNALKSCGGIHSKEKIIASMADKYILL 118

Query: 121 ADYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGN 180
            + +K   KL   Y   + +E++  +   +K + IS  GG+   RS+ AK G  +TD+GN
Sbjct: 119 TNESKFVKKLDSTYP--IVLEILEESAGYVKRR-ISEIGGKATFRSSAAKDGFTITDSGN 175

Query: 181 FILDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKA 220
            +LD +F ++  D +++   +K I GVVET LFV++  +A
Sbjct: 176 LLLD-VFFDELGDAKELQKGLKGITGVVETSLFVDLVSQA 214


>UniRef50_A6RS68 Cluster: Putative uncharacterized protein; n=2;
           Sclerotiniaceae|Rep: Putative uncharacterized protein -
           Botryotinia fuckeliana B05.10
          Length = 344

 Score =  110 bits (265), Expect = 3e-23
 Identities = 67/162 (41%), Positives = 93/162 (57%), Gaps = 19/162 (11%)

Query: 70  NLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTKDSVK 129
           +LG      ++DV  DGADE+D ++  IKGGG CL QEK++A+ SKK + +ADY K   +
Sbjct: 138 DLGLKGKRESLDVAFDGADEIDEDLNCIKGGGACLFQEKLVATSSKKFVCVADYRKLQPR 197

Query: 130 LGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLR-SAVAKAGPVVTDNGNFILDWMFA 188
           L   + K +PIE+ P+A   IK  +I+L   + K+R    AKAGPVVTDNG +I+D  F 
Sbjct: 198 LLTSW-KAIPIEIAPLAAPTIKRILITLGSPDPKIRQGGSAKAGPVVTDNGMWIIDAPFP 256

Query: 189 ---------------NQNLDWE--KVNNTIKLIPGVVETGLF 213
                           +N  WE   +   +K I GV+ETGLF
Sbjct: 257 KLLIHSDLKGNDKGDGENGTWEVHNLGRRLKRIVGVLETGLF 298


>UniRef50_UPI00015BAFE1 Cluster: ribose 5-phosphate isomerase; n=1;
           Ignicoccus hospitalis KIN4/I|Rep: ribose 5-phosphate
           isomerase - Ignicoccus hospitalis KIN4/I
          Length = 221

 Score =  109 bits (263), Expect = 5e-23
 Identities = 73/195 (37%), Positives = 112/195 (57%), Gaps = 17/195 (8%)

Query: 24  IFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIKHGLNLGELETNPNIDVT 83
           + GVGSG+TV   ++ L E   S       +PTS+     + KHGL + +L +   ++++
Sbjct: 22  VLGVGSGTTVRLFIKYLKEFGFSG----LTVPTSYDTALELKKHGLKVLDLMSVDEVELS 77

Query: 84  IDGADEV---DSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTKDSVKLGDRYKKGVPI 140
           +DGADEV   + ++  +KGGG  +L+EK++A  S+K I I D  K S   G    +GVP+
Sbjct: 78  VDGADEVFTMNGSLYAVKGGGAAMLREKVLAYISRKRIYIVDEGKVS---GSPCSRGVPV 134

Query: 141 --EVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFILDWMFANQNLDWEKVN 198
             EV+P + +P   + + L G   KLR A  K GPVVTDNGN ++D M    +++   V 
Sbjct: 135 PAEVVPSS-LPAVARGLKLLGVGWKLREAKGKLGPVVTDNGNLVID-MDCKSSIN---VI 189

Query: 199 NTIKLIPGVVETGLF 213
             ++ +PGV  TGLF
Sbjct: 190 EKVEALPGVAVTGLF 204


>UniRef50_Q03Y20 Cluster: Ribose 5-phosphate isomerase; n=1;
           Leuconostoc mesenteroides subsp. mesenteroides ATCC
           8293|Rep: Ribose 5-phosphate isomerase - Leuconostoc
           mesenteroides subsp. mesenteroides (strain ATCC 8293
           /NCDO 523)
          Length = 231

 Score =  109 bits (263), Expect = 5e-23
 Identities = 79/226 (34%), Positives = 119/226 (52%), Gaps = 10/226 (4%)

Query: 7   KQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIK 66
           K+ AA  A++ ++  + I G+G+GSTV Y +  LA    + +  V  + TS    Q   +
Sbjct: 8   KKQAALAALN-YIQTDMIIGLGTGSTVSYFLDALA----ASQYNVIGVTTSTITSQRCAE 62

Query: 67  HGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTKD 126
             + + +++   +IDVT+DGADEVDS +  IKGGG  LL EKI+A  SKK I I D +K 
Sbjct: 63  LNIPIVDIDAIDHIDVTVDGADEVDSYLNGIKGGGAALLMEKIVAKNSKKNIWIVDRSKV 122

Query: 127 SVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFILDWM 186
              LG      +P+EVIP     +  +  +  G   KLR       PV+TD G++I+D  
Sbjct: 123 HNTLG---SFPLPVEVIPYGSGQLLRQFAN-KGLFPKLRRHPGNNQPVITDAGHYIIDCH 178

Query: 187 FANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGNVVER 232
               N  +  +   ++   GVVE GLF+N+C +   G     + ER
Sbjct: 179 MTTINNPY-ALAEYLESQVGVVEHGLFLNICDRIIIGDNTVEIKER 223


>UniRef50_A5EVM0 Cluster: Ribose 5-phosphate isomerase; n=1;
           Dichelobacter nodosus VCS1703A|Rep: Ribose 5-phosphate
           isomerase - Dichelobacter nodosus (strain VCS1703A)
          Length = 218

 Score =  109 bits (261), Expect = 8e-23
 Identities = 82/225 (36%), Positives = 120/225 (53%), Gaps = 17/225 (7%)

Query: 7   KQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIK 66
           ++VAA  AV + V  N   GVGSGSTV+  ++ L +     +  V    TS +A +    
Sbjct: 8   EKVAA--AVLEHVPENITLGVGSGSTVLCFIEALKQAKRQFRDIVAASETSSKALEAA-- 63

Query: 67  HGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTKD 126
            G  + +L      D+ +DGADE++ +  +IKGGG  L +EKIIAS +K+ I I D +K 
Sbjct: 64  -GFRVRDLNACDPPDIYVDGADEINDDKIMIKGGGAALTREKIIASAAKEFICIIDESKK 122

Query: 127 SVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFILDWM 186
             +LG R+   V +EVIPMA   +  +I+ L G E + R        VVTDNG++ILD  
Sbjct: 123 VAQLG-RFP--VAVEVIPMARSYVAREIVKL-GAEPRWRQG------VVTDNGHWILDVH 172

Query: 187 FANQNLDWEKVNNTIKLIPGVVETGLFV-NMCCKAYFGQPEGNVV 230
           + +     E++   I  I GVVE G+F      K    Q +G +V
Sbjct: 173 YLDLTAA-ERMEARINTIAGVVECGIFAQRRADKVLMSQSDGEIV 216


>UniRef50_A5FY01 Cluster: Ribose 5-phosphate isomerase; n=1;
           Acidiphilium cryptum JF-5|Rep: Ribose 5-phosphate
           isomerase - Acidiphilium cryptum (strain JF-5)
          Length = 424

 Score =  108 bits (259), Expect = 1e-22
 Identities = 79/227 (34%), Positives = 123/227 (54%), Gaps = 12/227 (5%)

Query: 4   EQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQL 63
           E  K+ AA  AV   V +    G+G+GST  + + +L  RV +E L + C+ TS      
Sbjct: 6   ENGKRAAARLAVG-LVESGMRVGLGTGSTAAHFIDQLGARVRAEGLDIECVATSDLTAAR 64

Query: 64  IIKHGLNLGELETNPNIDVTIDGADEVD-SNMTLIKGGGGCLLQEKIIASCSKKLIVIAD 122
               GL L  L+ +  +D+ +DGADEV+   + LIKG GG LL+EK++A  +++ +VIAD
Sbjct: 65  AEFLGLRLVPLDGS--LDLAVDGADEVEFGTLRLIKGLGGALLREKLVAQSARRFVVIAD 122

Query: 123 YTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAG-PVVTDNGNF 181
            +K   +LG   K  +P+E++         ++  L    + LR   A AG P V+D G+F
Sbjct: 123 RSKLVTRLGAHSK--LPVEIVRHGADRTCARLAELDLAPV-LR---ANAGSPFVSDGGHF 176

Query: 182 ILDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGN 228
           I D     + +  E V + ++ I GVV TGLF++    A  G P+G+
Sbjct: 177 IADCTMP-KGIVPEAVESALRSIAGVVGTGLFLSGSACAIIGYPDGS 222


>UniRef50_O84215 Cluster: Ribose-5-phosphate isomerase A; n=7;
           Chlamydiaceae|Rep: Ribose-5-phosphate isomerase A -
           Chlamydia trachomatis
          Length = 242

 Score =  106 bits (254), Expect = 6e-22
 Identities = 72/228 (31%), Positives = 122/228 (53%), Gaps = 11/228 (4%)

Query: 7   KQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIK 66
           KQ  A +AV       C+ G+GSGST    +  L +RV +E+L +T + +S  ++ L   
Sbjct: 18  KQKLALEAVALVEPGMCV-GLGSGSTAREFILALGDRVRTERLVITAVASSRISQLLAEA 76

Query: 67  HGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTKD 126
            G+ L +     ++D+ +DGADEVD  + +IKGGGG L +EKI+    K+ +++ D  K 
Sbjct: 77  VGIPLSDHSLLQDVDLVVDGADEVDPCLRMIKGGGGALFREKILLQSGKRNVILVDERKL 136

Query: 127 SVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYG--GEIKLRSAVAKAGPVVTDNGNFILD 184
              LG   K  +PIE+ P     ++ +I++  G  GE +  SA  +    +TDNGN+I D
Sbjct: 137 VPTLG---KFSLPIEIAPFGCSSVQ-RILNKQGYFGEWRETSAGER---FITDNGNYIYD 189

Query: 185 WMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGNVVER 232
               +   + E+    +  I G+++ G FV    + + G  +G++V +
Sbjct: 190 VRTPDSYANPEEDMIRLLQIRGIIDVG-FVIAKAEVWVGYADGSIVRK 236


>UniRef50_Q4J990 Cluster: Ribose 5-phosphate isomerase; n=2;
           Sulfolobus|Rep: Ribose 5-phosphate isomerase -
           Sulfolobus acidocaldarius
          Length = 220

 Score =  105 bits (253), Expect = 7e-22
 Identities = 68/204 (33%), Positives = 113/204 (55%), Gaps = 9/204 (4%)

Query: 13  QAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIKHGLNLG 72
           Q V + +T   I G+G+G TV   ++ L       + K   I +S   +  I + G  + 
Sbjct: 9   QYVSKRLTGYSIIGLGTGRTVKKLIEHLDREGILNQFKY--IASSIDTELEISQRGGLIL 66

Query: 73  ELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTKDSVKLGD 132
            L +    D+ ID  D V  +  ++KGGG  LL+EKI+ + SK  + I +Y K  VK+ +
Sbjct: 67  SLYSGIQPDIYIDSFDVVTKDKVMVKGGGAALLREKILTTFSKSSLFIGEY-KKLVKI-E 124

Query: 133 RYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFILD-WMFANQN 191
           ++   VP+E++P++ + I  KI  + G +  +R    K G +++DNGN I+D  +  NQ 
Sbjct: 125 QHSVKVPVEIVPVSIMYILKKINEI-GFKTSIREGTGKMGGIISDNGNMIIDVEVRINQL 183

Query: 192 LDWEKVNNTIKLIPGVVETGLFVN 215
            +++K   TIK IPG++ETG+F N
Sbjct: 184 CEFDK---TIKSIPGIIETGVFCN 204


>UniRef50_Q62K38 Cluster: Ribose-5-phosphate isomerase A; n=132;
           Bacteria|Rep: Ribose-5-phosphate isomerase A -
           Burkholderia mallei (Pseudomonas mallei)
          Length = 231

 Score =  105 bits (251), Expect = 1e-21
 Identities = 73/204 (35%), Positives = 108/204 (52%), Gaps = 9/204 (4%)

Query: 10  AAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIKHGL 69
           AA + V + V    + GVG+GST    +  LA   +  +  V+   +S    + +  HG+
Sbjct: 13  AAARYVTENVPQGAVIGVGTGSTANCFIDALAAVKDRYRGAVS---SSVATTERLKSHGI 69

Query: 70  NLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTKDSVK 129
            + +L    ++ V +DGADE+D +  +IKGGGG L +EKI+AS ++  + IAD +K    
Sbjct: 70  KVFDLNEIESLQVYVDGADEIDGSGAMIKGGGGALTREKIVASVAETFVCIADASKRVAV 129

Query: 130 LGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFILDWMFAN 189
           LG   +  +P+EV+PMA   I  ++ +L GG   LR       P VTDNGN ILD     
Sbjct: 130 LG---QFPLPVEVVPMARTAIGRRLAAL-GGVPVLR-VKQDGAPYVTDNGNEILDVKGLR 184

Query: 190 QNLDWEKVNNTIKLIPGVVETGLF 213
            + D   +   I   PGVV  GLF
Sbjct: 185 ID-DPRALEAAINGWPGVVTVGLF 207


>UniRef50_Q8E4Y6 Cluster: Ribose-5-phosphate isomerase A; n=22;
           cellular organisms|Rep: Ribose-5-phosphate isomerase A -
           Streptococcus agalactiae serotype III
          Length = 223

 Score =  104 bits (249), Expect = 2e-21
 Identities = 75/232 (32%), Positives = 125/232 (53%), Gaps = 11/232 (4%)

Query: 3   LEQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQ 62
           +++ K++A   A  ++V N  I G+G+GST  + V+ +  RV+ E L+V  + TS +  +
Sbjct: 1   MDELKKLAGVTAA-KYVKNGMIVGLGTGSTAYFFVEEIGRRVKEEGLQVVGVTTSNRTTE 59

Query: 63  LIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIAD 122
                G+ L   +    IDVT+DGADEVD +   IKGGGG LL EKI+A+ +K+ I + D
Sbjct: 60  QARGLGIPLKSADDIDVIDVTVDGADEVDPDFNGIKGGGGALLMEKIVATPTKEYIWVVD 119

Query: 123 YTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGP-VVTDNGNF 181
            +K    LG  +K  +P+EV+         ++  ++  +    S     G   +TD GN+
Sbjct: 120 ESKLVETLG-AFK--LPVEVVRYG----SERLFRVFKSKGYCPSFRETEGDRFITDMGNY 172

Query: 182 ILDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEG-NVVER 232
           I+D +   +  D +++ N +    GVVE GLF +M  K       G +++E+
Sbjct: 173 IID-LDLKKIEDPKQLANELDHTVGVVEHGLFNSMVNKVIVAGKNGLDILEK 223


>UniRef50_Q97ZD9 Cluster: Ribose 5-phosphate isomerase; n=2;
           Sulfolobaceae|Rep: Ribose 5-phosphate isomerase -
           Sulfolobus solfataricus
          Length = 227

 Score =  102 bits (244), Expect = 9e-21
 Identities = 70/209 (33%), Positives = 108/209 (51%), Gaps = 9/209 (4%)

Query: 24  IFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIKHGLNLGELETNPNIDVT 83
           I GVG+G TV   ++ L+   E+ K     + +S   +  + K G  +  L +    ++ 
Sbjct: 20  IIGVGTGKTVKKLIEVLSSE-ENLKESSLFVASSIDTEIELSKRGFKVLSLFSAIQPEIY 78

Query: 84  IDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTKDSVKLGDRYKKGVPIEVI 143
           +D  D V  +  +IKGGGG LL+EK++A  SK  I I     +S KL D     +PIEVI
Sbjct: 79  VDSFDIVTKDGIMIKGGGGALLREKLLAYFSKYRIFIG----ESTKLKDTKVIDIPIEVI 134

Query: 144 PMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFILDWMFANQNLDWEKVNNTIKL 203
            +    +K K+  + G  +K+R    K GP+++DNGN ILD     +NL   + +  IK 
Sbjct: 135 SVGVSYVKYKLEKM-GFTVKIREGSGKMGPIISDNGNVILDVSVKTENLC--EFDRMIKN 191

Query: 204 IPGVVETGLFV-NMCCKAYFGQPEGNVVE 231
           IP +VETG+F   +  K      +G + E
Sbjct: 192 IPSIVETGIFCKELYNKIILANEQGRIEE 220


>UniRef50_Q97RI7 Cluster: Ribose-5-phosphate isomerase A; n=28;
           Lactobacillales|Rep: Ribose-5-phosphate isomerase A -
           Streptococcus pneumoniae
          Length = 227

 Score =  102 bits (244), Expect = 9e-21
 Identities = 73/231 (31%), Positives = 117/231 (50%), Gaps = 8/231 (3%)

Query: 3   LEQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQ 62
           +E  K++A   A + F+ +  + G+G+GST  Y V+ +  R++ E L++T + TS    +
Sbjct: 1   MENLKKMAGITAAE-FIKDGMVVGLGTGSTAYYFVEEIGRRIKEEGLQITAVTTSSVTSK 59

Query: 63  LIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIAD 122
                 + L  ++    +DVT+DGADEVDS    IKGGGG LL EK++A+ SK+ I + D
Sbjct: 60  QAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALLMEKVVATPSKEYIWVVD 119

Query: 123 YTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFI 182
            +K   KLG  +K  +P+EV+      +  +     G +   R    +    VTD  NFI
Sbjct: 120 ESKLVEKLG-AFK--LPVEVVQYGAEQV-FRHFERAGYKPSFREKDGQR--FVTDMQNFI 173

Query: 183 LDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGNVVERS 233
           +D +  +   +       +  + GVVE GLF  M  K      +G  +  S
Sbjct: 174 ID-LALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGVQISTS 223


>UniRef50_Q88YY5 Cluster: Ribose-5-phosphate isomerase A; n=3;
           Lactobacillales|Rep: Ribose-5-phosphate isomerase A -
           Lactobacillus plantarum
          Length = 227

 Score =  102 bits (244), Expect = 9e-21
 Identities = 75/232 (32%), Positives = 122/232 (52%), Gaps = 9/232 (3%)

Query: 1   MSLEQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQA 60
           M+ +Q KQ+   +AV+ ++ +    G+G+GSTV + V  L ERV++E L +  + TS + 
Sbjct: 1   MNQDQLKQLVGQKAVE-YIQDGMQVGLGTGSTVKFMVDALGERVKNEHLNIVGVSTSDRT 59

Query: 61  KQLIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVI 120
                  G+ +  ++   ++D+TIDGADE+  +   +KGGG  LL EKI+A  S K++ I
Sbjct: 60  AAQAKALGIPMKSVDEVDHLDLTIDGADEIADDFQGVKGGGAALLFEKIVAINSDKVMWI 119

Query: 121 ADYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGN 180
            D +K   +LG     G+P+EVIP     +  K ++  G     R    +   V TD+ N
Sbjct: 120 VDESKMVHQLG---AFGLPVEVIPYGSQHVFEK-MAARGYNPVFRKVNDEL--VRTDSNN 173

Query: 181 FILDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEG-NVVE 231
            I+D +  +   D   +   +  + GVVE GLF++M      G   G  V+E
Sbjct: 174 IIID-LHIDPITDPHALAEDLIHMVGVVEHGLFLDMVNTVIVGHANGPEVIE 224


>UniRef50_Q74KF3 Cluster: Ribose-5-phosphate isomerase A; n=3;
           Lactobacillus|Rep: Ribose-5-phosphate isomerase A -
           Lactobacillus johnsonii
          Length = 232

 Score =  101 bits (242), Expect = 2e-20
 Identities = 76/231 (32%), Positives = 118/231 (51%), Gaps = 10/231 (4%)

Query: 4   EQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVT-CIPTSFQAKQ 62
           +Q K+ AA +A  + V  N + GVG+GSTV + +  L ER E E   +   + TS ++K+
Sbjct: 7   DQLKKEAATKAA-KMVEPNSVLGVGTGSTVAFFIDALGERKEREGFSLKHIVTTSNRSKK 65

Query: 63  LIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIAD 122
            +   G  + EL      D+T+DGAD VD N+  IKGGGG L  EK +A  SKK+I I D
Sbjct: 66  QLEGLGFKVDELADIDQADLTVDGADRVDDNLDGIKGGGGALTLEKNVAINSKKIIWIVD 125

Query: 123 YTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGP-VVTDNGNF 181
            +K    L       +P+EV+P   V  +          +K +  +   G   VT  GN+
Sbjct: 126 ESKLVHHLSG---FPLPVEVLP---VSAEQNFKRFEAEGLKPQWRLNDEGKRYVTHYGNY 179

Query: 182 ILDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGNVVER 232
           I+D + A+       + + +    GVVE GLF++MC +      +G + ++
Sbjct: 180 IID-LAADPTPVPHGLADYLDHTVGVVEHGLFLDMCDEVIIAHSDGTIEDK 229


>UniRef50_Q5F831 Cluster: Ribose-5-phosphate isomerase A; n=5;
           Betaproteobacteria|Rep: Ribose-5-phosphate isomerase A -
           Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)
          Length = 223

 Score =  100 bits (240), Expect = 3e-20
 Identities = 71/211 (33%), Positives = 120/211 (56%), Gaps = 17/211 (8%)

Query: 4   EQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQL 63
           ++ K++AA +AV+ FV  N   G+G+GST+ + ++ L +    +K+K   + TS ++ +L
Sbjct: 5   DELKRIAAEKAVE-FVPENEYIGIGTGSTINFFIEALGK--SGKKIK-GAVSTSKKSGEL 60

Query: 64  IIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADY 123
           + ++ + +  L     + V IDGADEV+  + +IKGGGG  L EKI+AS S+K + IAD 
Sbjct: 61  LARYDIPVVSLNEVSGLAVYIDGADEVNHALQMIKGGGGAHLNEKIVASASEKFVCIADE 120

Query: 124 TKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFIL 183
           +K   +LG   K  +P+E +  A   +  K++++ GG+ +LR          T  GN I+
Sbjct: 121 SKYVSRLG---KFPLPVEAVESARSLVSRKLLAM-GGQPELRIG------YTTFYGNQIV 170

Query: 184 DWMFANQNLDWE-KVNNTIKLIPGVVETGLF 213
           D      N+D    + + I  I GV+E G+F
Sbjct: 171 D--VHGLNIDQPLTMEDEINKITGVLENGIF 199


>UniRef50_Q8P1C5 Cluster: Ribose-5-phosphate isomerase A; n=15;
           Lactobacillales|Rep: Ribose-5-phosphate isomerase A -
           Streptococcus pyogenes serotype M18
          Length = 227

 Score =   99 bits (238), Expect = 5e-20
 Identities = 74/228 (32%), Positives = 116/228 (50%), Gaps = 8/228 (3%)

Query: 3   LEQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQ 62
           +E  K++A   A  Q+VT+    G+G+GST  Y V+ +  RV+ E L+V  + TS    +
Sbjct: 1   MEALKKIAGVTAA-QYVTDGMTIGLGTGSTAYYFVEEIGRRVKQEGLQVVGVTTSSVTSK 59

Query: 63  LIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIAD 122
                G+ L  ++   +ID+T+DGADEVD +   IKGGG  LL EKI+A+ +K+ I + D
Sbjct: 60  QAEVLGIPLKSIDDIDSIDLTVDGADEVDKDFNGIKGGGAALLMEKIVATPTKEYIWVVD 119

Query: 123 YTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFI 182
            +K    LG  +K  +P+EV+      +  ++    G +   R  +     +VTD  N+I
Sbjct: 120 ASKMVEHLG-AFK--LPVEVVQYGADRL-FRVFEKAGYKPSFR--MKGDSRLVTDMQNYI 173

Query: 183 LDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGNVV 230
           +D +      D     + +    GVVE GLF  M  K      +G  V
Sbjct: 174 ID-LDLGCIKDPVAFGHLLDGTVGVVEHGLFNGMVDKVIVASKDGVTV 220


>UniRef50_A6E944 Cluster: Ribose 5-phosphate isomerase; n=1;
           Pedobacter sp. BAL39|Rep: Ribose 5-phosphate isomerase -
           Pedobacter sp. BAL39
          Length = 227

 Score = 99.1 bits (236), Expect = 8e-20
 Identities = 66/222 (29%), Positives = 113/222 (50%), Gaps = 7/222 (3%)

Query: 7   KQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIK 66
           KQ AA +A  + ++   + G+G+GST+ Y V+ +A    +    +T    S+    ++  
Sbjct: 5   KQQAATEAF-KLISKGQVIGLGAGSTIAYLVKTIAAD-HALASTLTFSSPSYDTVIMLND 62

Query: 67  HGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTKD 126
           H LN+   +    +D+  DG D++D  +  +K GGG    EKI+A  + + +++ DY K 
Sbjct: 63  HRLNVKPSDFLQGVDLYFDGCDQLDWQLNALKSGGGIHTYEKILAVMADEFVLLGDYGKL 122

Query: 127 SVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGG-EIKLRSAVAKAGPVVTDNGNFILDW 185
              L   Y   + IEV+P A   +   +   + G  + +R+   + GPV TD G +++D 
Sbjct: 123 VEHLDVTYP--LVIEVLPQALNVVSAILRKQFKGISLIIRTGDQRVGPVRTDGGCYLIDA 180

Query: 186 MFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEG 227
            F    L   ++ + IK+IPGVV+  LF  +  KA    PEG
Sbjct: 181 SFV--TLPGLELLDQIKMIPGVVDHSLFFKLADKAILAGPEG 220


>UniRef50_Q4FT49 Cluster: Ribose 5-phosphate isomerase; n=5;
           Gammaproteobacteria|Rep: Ribose 5-phosphate isomerase -
           Psychrobacter arcticum
          Length = 219

 Score = 97.5 bits (232), Expect = 3e-19
 Identities = 77/216 (35%), Positives = 118/216 (54%), Gaps = 21/216 (9%)

Query: 1   MSLEQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQA 60
           MS +QA++ AA +A  +++ ++ I GVG+GSTV      L E + + KL    + +S   
Sbjct: 1   MSDQQAQKQAAAKAALRYIEDDMILGVGTGSTV----NCLIELLPTLKL-AGAVASSQVT 55

Query: 61  KQLIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVI 120
           +  +   G+ + +L     +DV IDGADEV++++ LIKGGGG L +EKI+A+ S K + +
Sbjct: 56  EDRLRALGIEIVDLNFAGQLDVYIDGADEVNAHLQLIKGGGGALTREKIVAAASNKFVCM 115

Query: 121 ADYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGN 180
            D +K    LG  +   VPIEV+P A   +  ++  + GGE   R         VTD GN
Sbjct: 116 VDESKSVEILGRAFP--VPIEVLPQARSYVARQLARM-GGEPVYRE------DFVTDYGN 166

Query: 181 FILDWM---FANQNLDWEKVNNTIKLIPGVVETGLF 213
            ILD      +N     +++NN    I GVV  G+F
Sbjct: 167 VILDTYDLDVSNPLALEQQLNN----IVGVVCNGIF 198


>UniRef50_A3XYG4 Cluster: Ribose 5-phosphate isomerase; n=2;
           Vibrio|Rep: Ribose 5-phosphate isomerase - Vibrio sp.
           MED222
          Length = 235

 Score = 92.3 bits (219), Expect = 1e-17
 Identities = 70/210 (33%), Positives = 111/210 (52%), Gaps = 17/210 (8%)

Query: 5   QAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLI 64
           +A +VA  Q + + +T + + G+G+G+TV   +Q L E   S      C+ +S ++ + +
Sbjct: 17  KAAKVALEQVL-KTLTPSSVIGIGTGATVEVFIQLLKE---SGAEFAHCVSSSVRSSRAL 72

Query: 65  IKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYT 124
              GLN   +     +D  IDG DE  +    +KGGG  L +EK++A+ +   I IAD  
Sbjct: 73  SSAGLNEISISECGRVDFYIDGIDEGLTTGMTVKGGGAALAREKVLATLALSFITIADSG 132

Query: 125 KDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFILD 184
           +   +LG   K  +P+EV+P A   + N + SL GG   LR          TDNGN ILD
Sbjct: 133 RLVTQLG---KFPLPVEVLPAAQTAVFNALQSL-GGHPTLRQ------DCTTDNGNIILD 182

Query: 185 WMFANQNL-DWEKVNNTIKLIPGVVETGLF 213
              A+ ++ + +++   I  IPGVVE G+F
Sbjct: 183 --VAHLDIAEPKRLELQINAIPGVVENGIF 210


>UniRef50_A5BTA5 Cluster: Putative uncharacterized protein; n=1;
           Vitis vinifera|Rep: Putative uncharacterized protein -
           Vitis vinifera (Grape)
          Length = 237

 Score = 92.3 bits (219), Expect = 1e-17
 Identities = 69/220 (31%), Positives = 114/220 (51%), Gaps = 32/220 (14%)

Query: 1   MSLEQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLK-VTCIPTSFQ 59
           ++ ++ K++AAY+AV+ +V +  + G+G+GST  +AV R+ E +   KLK +  IPT   
Sbjct: 21  LTQDELKKIAAYKAVE-YVESGMVLGLGTGSTAKHAVDRIGELLRQGKLKNIVGIPT--- 76

Query: 60  AKQLIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIV 119
                         +E +P   V        D  + L+KG GG LL+EK++    KK +V
Sbjct: 77  --------------IEDDPRTSV--------DPYLNLVKGRGGSLLREKMVEGACKKFVV 114

Query: 120 IADYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLY---GGEIKLRSAVAKAGPVVT 176
           I D +K    LG      +P+E++P  +     ++  L+   G   KLR+      P VT
Sbjct: 115 IVDESKLVNYLGGS-GLAMPVEIVPFCWKFTAQRLQMLFEESGCVAKLRT-YQNGEPFVT 172

Query: 177 DNGNFILDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNM 216
           DN N+I+D  F  +  D +  ++ I  + GVVE G+F++M
Sbjct: 173 DNMNYIVDLYFKREIGDLKVASDAILRLAGVVEHGMFIDM 212


>UniRef50_Q9YEA9 Cluster: Ribose-5-phosphate isomerase A; n=1;
           Aeropyrum pernix|Rep: Ribose-5-phosphate isomerase A -
           Aeropyrum pernix
          Length = 237

 Score = 90.6 bits (215), Expect = 3e-17
 Identities = 63/194 (32%), Positives = 105/194 (54%), Gaps = 8/194 (4%)

Query: 24  IFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIKHGLNLGELETNPNIDVT 83
           + GVG+G TV+  ++  + R     + V   P+SF+    +   G ++G+      ++V 
Sbjct: 27  VLGVGTGRTVMRFLREASARGVEPGVAV---PSSFETAVELAGLGWSVGDPRVYRGVNVY 83

Query: 84  IDGADEVDSNMT-LIKGGGGCLLQEKIIASCSKKLIVIADYTKDSVKLGDRYKKGVPIEV 142
           +DGADE +     ++KGGGG LL EKI++S SK  I I    +   +LG+  K  VP+EV
Sbjct: 84  VDGADEAEPGRGYMVKGGGGALLGEKILSSRSKLNIFIVGEDRLVGRLGE--KTPVPVEV 141

Query: 143 IPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFILDWMFANQNLDWEKVNNTIK 202
            P  +V +    +   G   ++R++  K GPVV+D G  I+D +      D   + + ++
Sbjct: 142 EP-GFVSMVLASLEELGLNPRVRTSPGKRGPVVSDWGGVIVD-LLTGPLEDPRGLESMLR 199

Query: 203 LIPGVVETGLFVNM 216
            +PGV ETGLF+ +
Sbjct: 200 NVPGVRETGLFLGL 213


>UniRef50_Q8TUT8 Cluster: Ribose 5-phosphate isomerase; n=1;
           Methanopyrus kandleri|Rep: Ribose 5-phosphate isomerase
           - Methanopyrus kandleri
          Length = 212

 Score = 89.8 bits (213), Expect = 5e-17
 Identities = 68/208 (32%), Positives = 113/208 (54%), Gaps = 13/208 (6%)

Query: 7   KQVAAYQAVDQFVTNNC-IFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLII 65
           K+ AA +A ++       + GVG+G+TV   ++ L +R E++ L  T IP +  A + I 
Sbjct: 4   KRNAARKAAEEVCRRGYEVIGVGAGTTVEAFLEELVKR-EADVLVFTTIPGTIDACRRI- 61

Query: 66  KHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTK 125
             GLN+  +     + V IDGAD VD +  L+KGGG C   EK I   + +  V+ D   
Sbjct: 62  --GLNVTTIPPE-ELPVAIDGADAVDPDGNLLKGGGACHSLEKAIDYTADEFWVVVD--- 115

Query: 126 DSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFILDW 185
           +S  + + ++  VP+EV+   Y  +  + +  + GE++ R+   K GPVV+D+GN I+D 
Sbjct: 116 ESKLVENLWELPVPVEVLRGCY-ELTVRTLEEF-GEVRPRTCDEKYGPVVSDSGNPIVD- 172

Query: 186 MFANQNLDWEKVNNTIKLIPGVVETGLF 213
                + D  ++   +  +PGVVE G+F
Sbjct: 173 -LHVDDWDPAELERELNSVPGVVECGVF 199


>UniRef50_Q41DL3 Cluster: Ribose 5-phosphate isomerase; n=1;
           Exiguobacterium sibiricum 255-15|Rep: Ribose 5-phosphate
           isomerase - Exiguobacterium sibiricum 255-15
          Length = 232

 Score = 88.2 bits (209), Expect = 2e-16
 Identities = 65/210 (30%), Positives = 107/210 (50%), Gaps = 10/210 (4%)

Query: 4   EQAKQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQL 63
           EQ K++ A  A+ Q V N  I G+G+GST    +  L E V++   +V  + TS +  + 
Sbjct: 3   EQEKKMLAEAAIKQ-VKNGMILGLGTGSTTRSFIDALGEWVKAGG-EVQGVATSNETVEQ 60

Query: 64  IIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADY 123
             +  + L  LE   +ID+ IDG D++D    ++KGGGG L +EK++A  S++++    Y
Sbjct: 61  AKRLNIPLLSLEEATHIDLVIDGIDQIDPRFRVLKGGGGALFREKVVALMSREIL----Y 116

Query: 124 TKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFIL 183
             D+ K        +P+E+   A  P   + +     ++ LR    +  P VTD G+ IL
Sbjct: 117 LADASKFVHHLTGPLPVEIDAFAR-PYVERYLRDKQLDVTLREHDGQ--PFVTDGGHLIL 173

Query: 184 DWMFANQNLDWEKVNNTIKLIPGVVETGLF 213
           D +   +  D       +K + GV+ETG F
Sbjct: 174 D-VDLERVQDVRHFAQELKSLTGVLETGYF 202


>UniRef50_Q8SR79 Cluster: RIBOSE 5-PHOSPHATE ISOMERASE; n=1;
           Encephalitozoon cuniculi|Rep: RIBOSE 5-PHOSPHATE
           ISOMERASE - Encephalitozoon cuniculi
          Length = 201

 Score = 86.2 bits (204), Expect = 6e-16
 Identities = 62/198 (31%), Positives = 104/198 (52%), Gaps = 23/198 (11%)

Query: 19  VTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIKHGLNLGELETNP 78
           + N  + G+G+G+TV    +R  + +  +    T +P+S +   ++ + G  +     + 
Sbjct: 9   IANKTVIGIGTGTTV----ERYIDALHHD---ATYVPSSIRTALILSEKGFTVSSPLAHG 61

Query: 79  NIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTKDSVKLGDRYKKGV 138
            +D+ IDGAD  D N  +IKGGGG L  EK++ S +K+ I+I    K        +   +
Sbjct: 62  VLDLYIDGADYFDKNGNMIKGGGGALTTEKLLYSMAKETIIIVQSHKYRETFDGCF---I 118

Query: 139 PIEVIPMAYVPIKNKIISLYGGEIK--LRSAVAKAGPVVTDNGNFILDWMFANQNLDWEK 196
           P+E IP + + +   I +L G  +K  LR    K GP++TD GN I+D       ++++ 
Sbjct: 119 PVEAIPTSLLKL---ISTLEGSGLKYCLRETDGKMGPLITDLGNCIVD-------VEYDD 168

Query: 197 V-NNTIKLIPGVVETGLF 213
           V  ++ K I GVVE GLF
Sbjct: 169 VFISSCKSICGVVEHGLF 186


>UniRef50_Q88ZG6 Cluster: Ribose 5-phosphate epimerase; n=1;
           Lactobacillus plantarum|Rep: Ribose 5-phosphate
           epimerase - Lactobacillus plantarum
          Length = 222

 Score = 85.0 bits (201), Expect = 1e-15
 Identities = 64/227 (28%), Positives = 106/227 (46%), Gaps = 13/227 (5%)

Query: 7   KQVAAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIK 66
           KQ    QA+   +    + G G GSTV   V+  A  V      +T +  S   +QL   
Sbjct: 4   KQAIVQQALT-LIKPQMVVGFGGGSTVGELVKEAANHVND----ITVVTPSPTTRQLATV 58

Query: 67  HGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKK--LIVIADYT 124
            G  + +      +D+  DG D++D +   +K GGG    EKIIAS + +  L+ + D  
Sbjct: 59  LGYTVVDTAYCDRVDIAFDGCDQLDHHGNALKSGGGIHANEKIIASLADEYWLLTMQDRL 118

Query: 125 KDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFILD 184
            D   +    K  + +EV+P A + +  + +S  GG+  +R+A  + G  +TD+GN ++D
Sbjct: 119 VDQFDI----KTPLVLEVLPAA-LSLVMRTVSDLGGQATIRTANNRDGFTLTDSGNLLID 173

Query: 185 WMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCCKAYFGQPEGNVVE 231
             F         +N  +  + GVVET  F ++   A+ G    N V+
Sbjct: 174 CHFPTY-AKLTDLNVELATLAGVVETSYFDHLVTNAWLGDATTNTVK 219


>UniRef50_A2BLS3 Cluster: Ribose-5-phosphate isomerase A; n=1;
           Hyperthermus butylicus DSM 5456|Rep: Ribose-5-phosphate
           isomerase A - Hyperthermus butylicus (strain DSM 5456 /
           JCM 9403)
          Length = 254

 Score = 81.0 bits (191), Expect = 2e-14
 Identities = 65/213 (30%), Positives = 109/213 (51%), Gaps = 12/213 (5%)

Query: 26  GVGSGSTVVYAVQRLAERVESEKLKVTCI-PTSFQAKQLIIKHGLNLGELETNPNIDVTI 84
           G+G+GSTV   ++ L E   +  L+   +  +SF     + + G+   +      +DV  
Sbjct: 28  GIGTGSTVRLVLRFLIESPAASALRRAKVYASSFDTLLELRRLGIEAYDFLPRDGLDVYF 87

Query: 85  DGADEVD--SNMTL-IKGGGGCLLQEKIIASCSKKLIVIADYTKDSVKLGDRYKKGVPIE 141
           DGADEV   S+M + +KG G  +L+EK++A  S   +++ D +K S  LGD+  K VP+E
Sbjct: 88  DGADEVARVSDMCMAVKGRGAAMLREKLLAFNSAYTLLVVDESKVSRNLGDK-GKPVPVE 146

Query: 142 VIPMAYVPIKNKIISLYGGEIKLR-SAVAKAGPVVTDNGNFILD-WMFANQN-LDWEKVN 198
           V+P A   I  +  S  G   ++R +   + GP  TDN   ++D W +   + + +E + 
Sbjct: 147 VVPPAVETIVEEFES-RGIRAEVRTNCSCRDGPAFTDNYGIVIDTWPWGVMSPIQYESLL 205

Query: 199 NTIKLIPGVVETGLFVNMCCKAYFGQPEGNVVE 231
           +T   +PGV+  GLF+        G  +G   E
Sbjct: 206 DT---LPGVMGHGLFIGYMDAIVVGYGDGRSEE 235


>UniRef50_Q9FI13 Cluster: Similarity to ribose 5-phosphate
           isomerase; n=1; Arabidopsis thaliana|Rep: Similarity to
           ribose 5-phosphate isomerase - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 296

 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 61/222 (27%), Positives = 104/222 (46%), Gaps = 14/222 (6%)

Query: 10  AAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKL-KVTCIPTSFQAKQLIIKHG 68
           AA+  VD +V +  I G+GSG    +A++ L +++ S  L  V  +P S ++     K+G
Sbjct: 43  AAHHTVDNYVKSGMIIGLGSGEASDFAIRYLGQQLGSGSLHNVVGVPMSARSASEAAKYG 102

Query: 69  LNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTKDSV 128
           + L        ID     AD V+ N  +   G     QE       K ++ +AD     +
Sbjct: 103 IPLEYYRDGVQIDFAFHDADAVEENTLIAVIGRRRSSQEDDYILKQKSIVKVADEAVFMI 162

Query: 129 KLGDRYKKG----VPIEVIPMAYVPIKNKIISLYGGEIKL--RSAVAKAGP------VVT 176
           K  ++YK G    +P+ V  + ++ I  +I  LY G+ ++  R++V   GP      +VT
Sbjct: 163 K-EEQYKAGLEGSIPVLVQSLNWLAIAEEIDDLYLGDAEVWRRASVENEGPLGGDFPIVT 221

Query: 177 DNGNFILDWMFANQNLDWEKVNNTIKLIPGVVETGLFVNMCC 218
            +G+ ILD +F         +  ++  I GVV+ GL +   C
Sbjct: 222 SDGHNILDVIFTTPIRSLADLATSLDKIDGVVDHGLIIKTRC 263


>UniRef50_Q10CS9 Cluster: Ribose 5-phosphate isomerase, putative,
           expressed; n=6; Magnoliophyta|Rep: Ribose 5-phosphate
           isomerase, putative, expressed - Oryza sativa subsp.
           japonica (Rice)
          Length = 299

 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 61/219 (27%), Positives = 101/219 (46%), Gaps = 20/219 (9%)

Query: 10  AAYQAVDQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLK-VTCIPTSFQAKQLIIKHG 68
           AA   VD+FV +  + G+GSG     A+Q L  R+    L  +  IP+S  +    +K G
Sbjct: 58  AAKLTVDRFVESGMVVGLGSGPASGLAIQYLGTRLRRGSLTGILGIPSSTISASEAVKAG 117

Query: 69  LNLGELETNPNIDVTIDGADEVDSN-MTLIKG------GGGCLLQEKIIASCSKKLIVIA 121
           + +   E    ID     AD ++ + MT + G      G    + EK I   + KL  I 
Sbjct: 118 IQVSSYEEGTQIDFAFTDADIIEEDTMTAVIGRRKTESGEPSFMVEKGIVKSADKLAFII 177

Query: 122 DYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKL--RSAVAKAGPV----- 174
            + K  VK     +  +P+ V    ++    +I  L+ G+ ++  R ++  AGP+     
Sbjct: 178 GHEK-YVK---GIEGSIPVLVKSANWIDTAEEIDDLFLGDAEVWRRPSIGTAGPLGGDFP 233

Query: 175 -VTDNGNFILDWMFANQNLDWEKVNNTIKLIPGVVETGL 212
            VT  G+ +LD +F     D  KV  +++ I GVV+ G+
Sbjct: 234 LVTKEGHHVLDVIFTTPIPDLGKVAESLEKIAGVVDHGI 272


>UniRef50_Q1WS86 Cluster: Ribose 5-phosphate isomerase; n=1;
           Lactobacillus salivarius subsp. salivarius UCC118|Rep:
           Ribose 5-phosphate isomerase - Lactobacillus salivarius
           subsp. salivarius (strain UCC118)
          Length = 225

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 51/190 (26%), Positives = 90/190 (47%), Gaps = 7/190 (3%)

Query: 27  VGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIKHGLNLGELETNPNIDVTIDG 86
           +G GS V     +L++  E   +KV C P+ +  +Q+     LNL ++     I+   DG
Sbjct: 20  LGGGSNVKKLAHKLSQHPELN-IKV-CSPSEY-TRQICRDLNLNLIDITEASTIEFGFDG 76

Query: 87  ADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTKDSVKLGDRYKKGVPIEVIPMA 146
            D +D ++ ++K  GG    EK  A  ++K I+I+   +    L    +  + +    + 
Sbjct: 77  CDAIDFDLNVLKSNGGIHTLEKEYAYKAEKYIIISPPERLKASLNPNVQLCLEVVFPSVD 136

Query: 147 YVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFILDWMFANQNLDWEKVNNTIKLIPG 206
            V    K + L   E++L SAVA      T  GN+++D  +     D +K+N+ +  + G
Sbjct: 137 SVLFAAKQLGL-KAELRLGSAVASYAR--TPLGNYLID-CYCESWQDIKKINSKLSSLNG 192

Query: 207 VVETGLFVNM 216
           VV T  F N+
Sbjct: 193 VVSTSYFENI 202


>UniRef50_Q035R3 Cluster: Ribose 5-phosphate isomerase; n=1;
           Lactobacillus casei ATCC 334|Rep: Ribose 5-phosphate
           isomerase - Lactobacillus casei (strain ATCC 334)
          Length = 223

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 41/151 (27%), Positives = 67/151 (44%), Gaps = 4/151 (2%)

Query: 81  DVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTKDSVKLGDRYKKGVPI 140
           D+  DG D  D ++ L+K  GG    EK+ A  S   +++      + +L       + +
Sbjct: 68  DIAFDGCDSADKDLNLLKSNGGIHFYEKLHAQASHAYVILTAQKNVNAQLNAAVP--LTL 125

Query: 141 EVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNFILDWMFANQNLDWEKVNNT 200
           EV+  A   ++     L G + K R A    G   T +GN ++D   A    D  KV++ 
Sbjct: 126 EVVSAASEQVRAS-AKLLGLQAKRRMATTYMGYTRTRDGNELIDCTMAEWT-DIAKVDHL 183

Query: 201 IKLIPGVVETGLFVNMCCKAYFGQPEGNVVE 231
           +  +PGVV T  F ++        P+G V E
Sbjct: 184 LASLPGVVATSYFAHLATLLLIETPDGQVHE 214


>UniRef50_Q5FJW2 Cluster: Ribose 5-phosphate; n=1; Lactobacillus
           acidophilus|Rep: Ribose 5-phosphate - Lactobacillus
           acidophilus
          Length = 156

 Score = 49.2 bits (112), Expect = 9e-05
 Identities = 44/149 (29%), Positives = 67/149 (44%), Gaps = 9/149 (6%)

Query: 66  KHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTK 125
           K GL +  L     ID+  DG D +D ++  +K GG   L EKI A  SK+ I++    +
Sbjct: 13  KIGLFVHSLNETDQIDIAFDGCD-IDYSLNTLKSGGNIYLYEKIAAQMSKEYILLLPQER 71

Query: 126 DSVKLGDRYKKGVPIEVIPMAYVPIKNKIISL-YGGEIKLRSAVAKAGPVVTDNGNFILD 184
              +L    K  + IEV       I N   SL    E++L ++     P+    GN I+D
Sbjct: 72  IQKELST--KVPLSIEVASPTVKQIMNFCHSLNLKAELRLDTSSFARSPL----GNLIID 125

Query: 185 WMFANQNLDWEKVNNTIKLIPGVVETGLF 213
               N N D  ++N  +    GV+ +  F
Sbjct: 126 IYKPNWN-DIAQINEQLLKQNGVIASSYF 153


>UniRef50_O67166 Cluster: Gamma-glutamyl phosphate reductase; n=11;
           Bacteria|Rep: Gamma-glutamyl phosphate reductase -
           Aquifex aeolicus
          Length = 435

 Score = 40.7 bits (91), Expect = 0.031
 Identities = 42/200 (21%), Positives = 89/200 (44%), Gaps = 8/200 (4%)

Query: 3   LEQAKQVAAYQAV-DQFVTNNCIFGVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAK 61
           +E+AK++    AV D+ V N+    +     V+  V  L + V  E +K+  +P   +  
Sbjct: 52  VEKAKEMGLRPAVVDRLVLNDK--RIDGMVKVLKDVASLPDPV-GEIIKMWNLPNGLKVG 108

Query: 62  QLIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIA 121
           ++ +  G+     E+ PN+ +         SN  +++GG   +   K + +  K+     
Sbjct: 109 RMRVPLGVIFIVYESRPNVTIEASSLCMKSSNAVILRGGKEAINSNKALVNLIKEACRET 168

Query: 122 DYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNF 181
            + +D+V+  DR ++ +  E++ M     K  +    GGE  +R+ V  A   V  +   
Sbjct: 169 GFPEDAVQFIDRSEREIVWEILKMEG---KIDVAIPRGGESLIRAVVEHAKVPVIKHYKG 225

Query: 182 ILDWMFANQNLDWEKVNNTI 201
           + + ++ +   D EK  + +
Sbjct: 226 VCN-IYVDDEADLEKAYHIV 244


>UniRef50_A5V6Z7 Cluster: Sensor protein; n=1; Sphingomonas
           wittichii RW1|Rep: Sensor protein - Sphingomonas
           wittichii RW1
          Length = 767

 Score = 37.1 bits (82), Expect = 0.39
 Identities = 18/63 (28%), Positives = 33/63 (52%), Gaps = 5/63 (7%)

Query: 137 GVPIEVIPMAYVPIKNKIIS-----LYGGEIKLRSAVAKAGPVVTDNGNFILDWMFANQN 191
           GVP+EV  ++Y+     ++      + G +I+LR ++A+   +    G+ + DW  A  N
Sbjct: 92  GVPVEVRALSYLDEGRLVVQASCRDISGADIELRDSLARFHAIARATGDVVWDWDLATDN 151

Query: 192 LDW 194
           L W
Sbjct: 152 LWW 154


>UniRef50_P19320 Cluster: Vascular cell adhesion protein 1
           precursor; n=27; Eutheria|Rep: Vascular cell adhesion
           protein 1 precursor - Homo sapiens (Human)
          Length = 739

 Score = 36.7 bits (81), Expect = 0.51
 Identities = 30/127 (23%), Positives = 57/127 (44%), Gaps = 6/127 (4%)

Query: 31  STVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIKHGLNLGELE-TNPNIDVTIDGADE 89
           +TV+ +   + E  E   + +TC+   F A +++    L  GEL+  + N  +T+     
Sbjct: 514 TTVLVSPSSILE--EGSSVNMTCLSQGFPAPKILWSRQLPNGELQPLSENATLTLISTKM 571

Query: 90  VDSNMTLIKG---GGGCLLQEKIIASCSKKLIVIADYTKDSVKLGDRYKKGVPIEVIPMA 146
            DS + L +G    G    + ++I   + K I +  +  +SVK GD          +P  
Sbjct: 572 EDSGVYLCEGINQAGRSRKEVELIIQVTPKDIKLTAFPSESVKEGDTVIISCTCGNVPET 631

Query: 147 YVPIKNK 153
           ++ +K K
Sbjct: 632 WIILKKK 638


>UniRef50_Q6C6M6 Cluster: Similar to CA0775|CaIFK2 Candida albicans;
           n=1; Yarrowia lipolytica|Rep: Similar to CA0775|CaIFK2
           Candida albicans - Yarrowia lipolytica (Candida
           lipolytica)
          Length = 511

 Score = 35.5 bits (78), Expect = 1.2
 Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 1/66 (1%)

Query: 35  YAVQRLAERVESEKLKVTCIPTSFQAKQLIIKHGLNLGELETNPNIDVTIDGADEVDSNM 94
           +A Q + ++   +  KV      F  K+LI   G  LG    NPN+++T D   +V+SN 
Sbjct: 277 HATQNIRKKSPEKYWKVLKPDYEFACKRLIFDCGY-LGPALNNPNMELTFDRVVKVESNK 335

Query: 95  TLIKGG 100
            + K G
Sbjct: 336 VITKDG 341


>UniRef50_Q22B19 Cluster: Putative uncharacterized protein; n=1;
           Tetrahymena thermophila SB210|Rep: Putative
           uncharacterized protein - Tetrahymena thermophila SB210
          Length = 463

 Score = 34.7 bits (76), Expect = 2.1
 Identities = 17/60 (28%), Positives = 32/60 (53%)

Query: 98  KGGGGCLLQEKIIASCSKKLIVIADYTKDSVKLGDRYKKGVPIEVIPMAYVPIKNKIISL 157
           K G  C+  +  I++  KKL+++  Y KD     D +K  + IE+  + Y+  +N  ++L
Sbjct: 195 KVGTYCVSIKTNISNDGKKLVILKSYEKDQQMSSDEFKNELQIEIDILNYIQQQNTQVTL 254


>UniRef50_A2Q8F6 Cluster: Putative uncharacterized protein; n=1;
           Aspergillus niger|Rep: Putative uncharacterized protein
           - Aspergillus niger
          Length = 382

 Score = 34.3 bits (75), Expect = 2.7
 Identities = 33/133 (24%), Positives = 55/133 (41%), Gaps = 16/133 (12%)

Query: 69  LNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASCSKKLIVIADYTKDSV 128
           +N G   + P+     +G   ++    +  GGG         A+C K L V+A    +S 
Sbjct: 176 MNRGRCGSKPDAVCWTEGTRTIERKKQVTYGGGS--------ATCKKNLPVLAK-PYEST 226

Query: 129 KLGDRYKKG-----VPIE--VIPMAYVPIKNKIISLYGGEIKLRSAVAKAGPVVTDNGNF 181
            L  +  KG      PIE  +I M        I    GG I++++A  +   ++   G+ 
Sbjct: 227 TLAGKSDKGCSANSTPIEPMLIAMPRAACHTDIFIQTGGNIEIQAANVRRTVLLEGRGDG 286

Query: 182 ILDWMFANQNLDW 194
            L   +A +NL W
Sbjct: 287 TLSGWWAGRNLSW 299


>UniRef50_UPI0000F1E6F4 Cluster: PREDICTED: similar to regulatory
            factor X domain containing 2 homolog; n=1; Danio
            rerio|Rep: PREDICTED: similar to regulatory factor X
            domain containing 2 homolog - Danio rerio
          Length = 1466

 Score = 33.5 bits (73), Expect = 4.8
 Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 1/63 (1%)

Query: 144  PMAYVPIKNKIISLYGGEIKLRSAVAKAG-PVVTDNGNFILDWMFANQNLDWEKVNNTIK 202
            P A+ PI + I   + G     S V     P+ T  G   L+WM +  N +    NN I 
Sbjct: 1033 PFAFTPINSSITGYHDGSTVSSSPVKPMQRPMATHPGKTKLEWMNSGYNNNGGNSNNGIS 1092

Query: 203  LIP 205
            ++P
Sbjct: 1093 ILP 1095


>UniRef50_A6PGC1 Cluster: Sensor protein; n=1; Shewanella sediminis
           HAW-EB3|Rep: Sensor protein - Shewanella sediminis
           HAW-EB3
          Length = 483

 Score = 33.5 bits (73), Expect = 4.8
 Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 1/72 (1%)

Query: 60  AKQLIIKHGLNLGELETNPNIDVTIDGADEVDSNMTLIKGGGGCLLQEKIIASC-SKKLI 118
           A  L+ K      E E   NID  ID  DE+   +         L QE+ + +C SK+LI
Sbjct: 259 ATGLLRKRCQQADERELLDNIDCYIDDIDELTRQVLTFSKLNTTLSQEECLKACQSKQLI 318

Query: 119 VIADYTKDSVKL 130
            + +Y K  V+L
Sbjct: 319 NLDEYFKSRVQL 330


>UniRef50_Q6FTF7 Cluster: Similar to tr|Q08926 Saccharomyces
           cerevisiae YPL186c; n=1; Candida glabrata|Rep: Similar
           to tr|Q08926 Saccharomyces cerevisiae YPL186c - Candida
           glabrata (Yeast) (Torulopsis glabrata)
          Length = 227

 Score = 33.5 bits (73), Expect = 4.8
 Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 3/71 (4%)

Query: 141 EVIPMAYVPIKNKIISLYGGEIKLRSAVAKAG-PVVTDNGNFILDWMFANQNLDWEKVNN 199
           E++PM + P K +       E K+ +AV K     + D GN+  D  +A + +D     N
Sbjct: 26  EIVPMQWSPAKEQWEYELDLE-KIPAAVTKIHFKFIDDQGNWFTDSNYAKE-IDEHNNEN 83

Query: 200 TIKLIPGVVET 210
            +KL+PG  ET
Sbjct: 84  NVKLLPGHQET 94


>UniRef50_O28109 Cluster: 2-nitropropane dioxygenase; n=1;
           Archaeoglobus fulgidus|Rep: 2-nitropropane dioxygenase -
           Archaeoglobus fulgidus
          Length = 274

 Score = 33.5 bits (73), Expect = 4.8
 Identities = 28/91 (30%), Positives = 46/91 (50%), Gaps = 7/91 (7%)

Query: 29  SGSTVVYAVQRLAERVESEKLKV-TCIPTSFQAKQLIIKHGLN----LGELETNPNIDVT 83
           SG+ V++ V RL E +++EK  V   +   F+A  +I + G+     + EL  N +I V 
Sbjct: 108 SGAKVIHKVSRLKEGLKAEKAGVDAVVAMGFEAGGIIGRSGVTSFCLIPELADNLSIPVV 167

Query: 84  IDG--ADEVDSNMTLIKGGGGCLLQEKIIAS 112
             G  ADE      LI G  G  +  +++A+
Sbjct: 168 AAGGIADERGFAAALILGAEGVEIGTRLLAT 198


>UniRef50_Q55CU4 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 942

 Score = 33.1 bits (72), Expect = 6.3
 Identities = 20/73 (27%), Positives = 39/73 (53%), Gaps = 4/73 (5%)

Query: 107 EKIIASCSKKLIVIADYTKDSVKLGDRYKKGVPIEVIPMAYVPIKN--KIISLYGGEIKL 164
           E  +A+C K+L++  ++T  S  L D + K  P++++ ++ +P KN  +I+ L    + L
Sbjct: 227 EYYLATCLKELLLTDEFTLTS--LADTFPKLQPLQLLQLSLLPFKNIYEILDLRLNFVNL 284

Query: 165 RSAVAKAGPVVTD 177
            S      P+  D
Sbjct: 285 SSTYQIYAPLPND 297


>UniRef50_Q3JDC9 Cluster: Putative uncharacterized protein; n=3;
           Gammaproteobacteria|Rep: Putative uncharacterized
           protein - Nitrosococcus oceani (strain ATCC 19707 /
           NCIMB 11848)
          Length = 908

 Score = 32.7 bits (71), Expect = 8.3
 Identities = 15/59 (25%), Positives = 29/59 (49%)

Query: 26  GVGSGSTVVYAVQRLAERVESEKLKVTCIPTSFQAKQLIIKHGLNLGELETNPNIDVTI 84
           G G  + +VY +Q++  R       +    +     Q    HGL++ ++  NPN+DV++
Sbjct: 498 GAGKSALLVYLLQQMMARHRPRIFIIEAGASFSLLGQHFAHHGLSVNQITLNPNVDVSL 556


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.136    0.392 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 260,462,638
Number of Sequences: 1657284
Number of extensions: 10999343
Number of successful extensions: 24431
Number of sequences better than 10.0: 107
Number of HSP's better than 10.0 without gapping: 94
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 24087
Number of HSP's gapped (non-prelim): 121
length of query: 237
length of database: 575,637,011
effective HSP length: 98
effective length of query: 139
effective length of database: 413,223,179
effective search space: 57438021881
effective search space used: 57438021881
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 71 (32.7 bits)

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