BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000927-TA|BGIBMGA000927- PA|IPR000175|Sodium:neurotransmitter symporter (632 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q9W1J0 Cluster: Transporter; n=10; Eumetazoa|Rep: Trans... 932 0.0 UniRef50_Q7QDY5 Cluster: Transporter; n=1; Anopheles gambiae str... 725 0.0 UniRef50_UPI0000586FC3 Cluster: PREDICTED: similar to IP14091p i... 581 e-164 UniRef50_P48067 Cluster: Sodium- and chloride-dependent glycine ... 562 e-159 UniRef50_UPI00005841AC Cluster: PREDICTED: similar to glycine tr... 555 e-156 UniRef50_Q9Y345 Cluster: Sodium- and chloride-dependent glycine ... 546 e-154 UniRef50_UPI0000E47D36 Cluster: PREDICTED: similar to glycine tr... 537 e-151 UniRef50_UPI0000E49167 Cluster: PREDICTED: similar to solute car... 530 e-149 UniRef50_Q99884 Cluster: Sodium-dependent proline transporter; n... 525 e-147 UniRef50_Q9UN76 Cluster: Sodium- and chloride-dependent neutral ... 517 e-145 UniRef50_A7SXK0 Cluster: Predicted protein; n=2; Nematostella ve... 510 e-143 UniRef50_UPI00015B5244 Cluster: PREDICTED: similar to sodium/shl... 504 e-141 UniRef50_UPI0000E47DA5 Cluster: PREDICTED: similar to solute car... 502 e-140 UniRef50_Q7K4Y6 Cluster: GH22929p; n=8; Pancrustacea|Rep: GH2292... 495 e-138 UniRef50_Q6NND1 Cluster: Transporter; n=14; Endopterygota|Rep: T... 488 e-136 UniRef50_Q0X0E9 Cluster: Amino acid transporter; n=1; Crassostre... 484 e-135 UniRef50_Q1ECY9 Cluster: Transporter; n=2; Danio rerio|Rep: Tran... 479 e-134 UniRef50_P48066 Cluster: Sodium- and chloride-dependent GABA tra... 479 e-133 UniRef50_P48029 Cluster: Sodium- and chloride-dependent creatine... 479 e-133 UniRef50_P31649 Cluster: Sodium- and chloride-dependent GABA tra... 472 e-131 UniRef50_A7S977 Cluster: Predicted protein; n=3; Nematostella ve... 467 e-130 UniRef50_Q4SW66 Cluster: Transporter; n=2; Tetraodontidae|Rep: T... 462 e-128 UniRef50_UPI0000E465AB Cluster: PREDICTED: similar to GABA neuro... 460 e-128 UniRef50_UPI0000E48F61 Cluster: PREDICTED: similar to glycine tr... 460 e-128 UniRef50_Q8WPM9 Cluster: Similar to glycine transporter; n=1; Oi... 459 e-127 UniRef50_P31641 Cluster: Sodium- and chloride-dependent taurine ... 457 e-127 UniRef50_UPI00015B5724 Cluster: PREDICTED: similar to GABA neuro... 454 e-126 UniRef50_UPI0000D5722E Cluster: PREDICTED: similar to solute car... 452 e-125 UniRef50_Q8MZK8 Cluster: Na+/Cl-dependent neurotransmitter trans... 452 e-125 UniRef50_Q20C86 Cluster: Transporter; n=1; Drosophila virilis|Re... 449 e-124 UniRef50_UPI0000587A15 Cluster: PREDICTED: similar to amino acid... 446 e-123 UniRef50_A7S7X6 Cluster: Predicted protein; n=3; Nematostella ve... 444 e-123 UniRef50_UPI000051A316 Cluster: PREDICTED: similar to CG1732-PA,... 443 e-123 UniRef50_Q01959 Cluster: Sodium-dependent dopamine transporter; ... 442 e-122 UniRef50_Q3I1M7 Cluster: Serotonin transporter; n=5; Schistosoma... 442 e-122 UniRef50_Q2ABP4 Cluster: Taurine transporter; n=2; Pteriomorphia... 439 e-121 UniRef50_Q7Q4L1 Cluster: Transporter; n=1; Anopheles gambiae str... 436 e-121 UniRef50_P31645 Cluster: Sodium-dependent serotonin transporter;... 434 e-120 UniRef50_UPI0000E4A7A9 Cluster: PREDICTED: similar to choline tr... 426 e-117 UniRef50_Q5J2D5 Cluster: GABA transporter protein; n=2; Caenorha... 426 e-117 UniRef50_Q03614 Cluster: Sodium-dependent dopamine transporter; ... 425 e-117 UniRef50_P51905 Cluster: Sodium-dependent serotonin transporter;... 424 e-117 UniRef50_UPI0000E47635 Cluster: PREDICTED: similar to high-affin... 418 e-115 UniRef50_UPI00015B4B04 Cluster: PREDICTED: similar to neurotrans... 417 e-115 UniRef50_Q9VLY6 Cluster: Transporter; n=7; Endopterygota|Rep: Tr... 416 e-115 UniRef50_Q4F9L7 Cluster: High-affinity octopamine transporter pr... 409 e-113 UniRef50_UPI000051A91B Cluster: PREDICTED: similar to inebriated... 409 e-112 UniRef50_Q9N3C7 Cluster: Transporter; n=3; Caenorhabditis|Rep: T... 407 e-112 UniRef50_Q7YZB6 Cluster: Sodium and chloride dependent proline t... 405 e-111 UniRef50_A4QNW3 Cluster: Transporter; n=10; Clupeocephala|Rep: T... 401 e-110 UniRef50_Q0PKT4 Cluster: High-affinity octopamine transporter; n... 400 e-110 UniRef50_O76689 Cluster: Sodium-dependent acetylcholine transpor... 397 e-109 UniRef50_Q9VR07 Cluster: Sodium- and chloride-dependent GABA tra... 393 e-108 UniRef50_O17372 Cluster: Sodium:neurotransmitter symporter famil... 388 e-106 UniRef50_Q7K330 Cluster: Transporter; n=11; Diptera|Rep: Transpo... 384 e-105 UniRef50_Q9W4C5 Cluster: Uncharacterized sodium-dependent transp... 384 e-105 UniRef50_UPI00015B40E0 Cluster: PREDICTED: similar to glycine tr... 378 e-103 UniRef50_UPI000069E376 Cluster: Orphan sodium- and chloride-depe... 378 e-103 UniRef50_Q4S8W1 Cluster: Transporter; n=2; Tetraodontidae|Rep: T... 376 e-103 UniRef50_UPI0000D56C9C Cluster: PREDICTED: similar to CG3252-PA;... 376 e-102 UniRef50_UPI0000E4659C Cluster: PREDICTED: similar to GABA trans... 375 e-102 UniRef50_UPI0000E4A90B Cluster: PREDICTED: similar to ENSANGP000... 373 e-101 UniRef50_UPI0000EB09CC Cluster: UPI0000EB09CC related cluster; n... 371 e-101 UniRef50_UPI0000DB6B93 Cluster: PREDICTED: similar to CG3252-PA;... 370 e-101 UniRef50_UPI0000DB6B91 Cluster: PREDICTED: similar to CG3252-PA;... 361 2e-98 UniRef50_A1Z8V9 Cluster: Transporter; n=3; Drosophila melanogast... 359 9e-98 UniRef50_Q4T2D0 Cluster: Transporter; n=3; Euteleostomi|Rep: Tra... 359 1e-97 UniRef50_A1L1P6 Cluster: Transporter; n=3; Danio rerio|Rep: Tran... 357 5e-97 UniRef50_Q17EZ6 Cluster: Sodium/shloride dependent amino acid tr... 356 1e-96 UniRef50_Q4T523 Cluster: Transporter; n=6; Tetraodontidae|Rep: T... 351 3e-95 UniRef50_Q9VSV2 Cluster: Transporter; n=3; Sophophora|Rep: Trans... 350 8e-95 UniRef50_Q4SBR4 Cluster: Transporter; n=8; Euteleostomi|Rep: Tra... 347 4e-94 UniRef50_Q620M8 Cluster: Transporter; n=2; Caenorhabditis|Rep: T... 342 2e-92 UniRef50_Q4RY29 Cluster: Transporter; n=2; Tetraodontidae|Rep: T... 339 1e-91 UniRef50_UPI0000660336 Cluster: Homolog of Homo sapiens "Solute ... 338 3e-91 UniRef50_UPI0000E481CA Cluster: PREDICTED: similar to solute car... 332 1e-89 UniRef50_Q7QGR3 Cluster: Transporter; n=1; Anopheles gambiae str... 332 2e-89 UniRef50_Q9W4S0 Cluster: Transporter; n=14; Eumetazoa|Rep: Trans... 331 3e-89 UniRef50_Q17EZ8 Cluster: Sodium/shloride dependent amino acid tr... 330 5e-89 UniRef50_Q9XUG5 Cluster: Transporter; n=3; Caenorhabditis|Rep: T... 326 1e-87 UniRef50_O76188 Cluster: Potassium coupled amino acid transporte... 322 2e-86 UniRef50_UPI000065F69C Cluster: Homolog of Homo sapiens "Solute ... 315 2e-84 UniRef50_UPI0000DB790C Cluster: PREDICTED: similar to CG5549-PA;... 313 8e-84 UniRef50_UPI0000E4A4BA Cluster: PREDICTED: similar to glycine tr... 312 2e-83 UniRef50_P90890 Cluster: Transporter; n=2; Caenorhabditis|Rep: T... 305 3e-81 UniRef50_Q59DZ2 Cluster: Transporter; n=4; Sophophora|Rep: Trans... 302 2e-80 UniRef50_UPI0000E49DFE Cluster: PREDICTED: similar to taurine tr... 291 4e-77 UniRef50_Q5XIV7 Cluster: Transporter; n=2; Eutheria|Rep: Transpo... 287 6e-76 UniRef50_Q4SBR5 Cluster: Transporter; n=1; Tetraodon nigroviridi... 276 2e-72 UniRef50_A7RFF4 Cluster: Predicted protein; n=1; Nematostella ve... 275 3e-72 UniRef50_Q4RX19 Cluster: Transporter; n=1; Tetraodon nigroviridi... 273 1e-71 UniRef50_O45813 Cluster: Transporter; n=2; Caenorhabditis|Rep: T... 269 2e-70 UniRef50_Q4SR96 Cluster: Transporter; n=4; cellular organisms|Re... 258 3e-67 UniRef50_A6LMJ8 Cluster: Sodium:neurotransmitter symporter precu... 254 7e-66 UniRef50_A1ZBC7 Cluster: Transporter; n=5; Diptera|Rep: Transpor... 250 9e-65 UniRef50_UPI000066095C Cluster: Homolog of Brachydanio rerio "Gl... 246 1e-63 UniRef50_O18288 Cluster: Transporter; n=1; Caenorhabditis elegan... 238 4e-61 UniRef50_Q2AHK9 Cluster: Transporter; n=1; Halothermothrix oreni... 237 9e-61 UniRef50_UPI0000DC2074 Cluster: UPI0000DC2074 related cluster; n... 236 1e-60 UniRef50_Q8IRU1 Cluster: Transporter; n=2; Diptera|Rep: Transpor... 231 4e-59 UniRef50_Q2QAU1 Cluster: Transporter; n=2; Didelphinae|Rep: Tran... 231 6e-59 UniRef50_A1I9V5 Cluster: Sodium-and chloride-dependent transport... 228 3e-58 UniRef50_Q9U2E3 Cluster: Transporter; n=1; Caenorhabditis elegan... 227 9e-58 UniRef50_Q8MZ19 Cluster: Transporter; n=7; Endopterygota|Rep: Tr... 227 9e-58 UniRef50_UPI0000ECA0A4 Cluster: Orphan sodium- and chloride-depe... 225 2e-57 UniRef50_A3QK28 Cluster: Novel protein similar to vertebrate sol... 216 2e-54 UniRef50_Q13032 Cluster: GABA/noradrenaline transporter; n=2; Ho... 213 2e-53 UniRef50_Q58715 Cluster: Uncharacterized sodium-dependent transp... 210 6e-53 UniRef50_UPI0000E460AF Cluster: PREDICTED: similar to inebriated... 209 1e-52 UniRef50_Q9NP91 Cluster: Sodium- and chloride-dependent transpor... 206 2e-51 UniRef50_Q4SBR6 Cluster: Transporter; n=1; Tetraodon nigroviridi... 203 1e-50 UniRef50_Q4AKJ6 Cluster: Transporter; n=4; Bacteria|Rep: Transpo... 200 1e-49 UniRef50_UPI00015A63D4 Cluster: Sodium-dependent dopamine transp... 199 2e-49 UniRef50_Q8TQM2 Cluster: Sodium/chloride-dependent noradrenaline... 196 1e-48 UniRef50_UPI00006CA50D Cluster: Sodium:neurotransmitter symporte... 194 5e-48 UniRef50_Q4SNN5 Cluster: Transporter; n=1; Tetraodon nigroviridi... 185 4e-45 UniRef50_A0UVQ7 Cluster: Transporter; n=5; Clostridium|Rep: Tran... 183 1e-44 UniRef50_Q4RSW5 Cluster: Transporter; n=2; Tetraodontidae|Rep: T... 183 1e-44 UniRef50_A0DZD7 Cluster: Transporter; n=3; Paramecium tetraureli... 181 5e-44 UniRef50_Q1NTI5 Cluster: Transporter; n=2; delta proteobacterium... 180 1e-43 UniRef50_O50649 Cluster: TnaT protein; n=1; Symbiobacterium ther... 173 9e-42 UniRef50_Q9KQI6 Cluster: Sodium-dependent transporter; n=34; Pro... 171 6e-41 UniRef50_A7RZ73 Cluster: Predicted protein; n=1; Nematostella ve... 170 8e-41 UniRef50_UPI0000661366 Cluster: Sodium- and chloride-dependent g... 170 1e-40 UniRef50_Q6PBA3 Cluster: Solute carrier family 6 (Neurotransmitt... 168 3e-40 UniRef50_O44752 Cluster: Sodium:neurotransmitter symporter famil... 167 8e-40 UniRef50_Q695T7 Cluster: Sodium-dependent neutral amino acid tra... 165 3e-39 UniRef50_Q9H2J7 Cluster: Orphan sodium- and chloride-dependent n... 164 7e-39 UniRef50_Q8ENV8 Cluster: Sodium-dependent transporter; n=18; Bac... 161 4e-38 UniRef50_Q1RLZ0 Cluster: Transporter; n=21; Euteleostomi|Rep: Tr... 161 5e-38 UniRef50_Q4SIS1 Cluster: Transporter; n=1; Tetraodon nigroviridi... 161 7e-38 UniRef50_O45915 Cluster: Transporter; n=2; Caenorhabditis|Rep: T... 157 6e-37 UniRef50_A4AIT5 Cluster: Transporter; n=1; marine actinobacteriu... 155 3e-36 UniRef50_O88575 Cluster: Sodium- and chloride-dependent transpor... 155 3e-36 UniRef50_Q8BPL9 Cluster: 0 day neonate eyeball cDNA, RIKEN full-... 154 8e-36 UniRef50_Q9CMU0 Cluster: Transporter; n=3; Pasteurellaceae|Rep: ... 154 8e-36 UniRef50_UPI0001554745 Cluster: PREDICTED: similar to glycine tr... 150 1e-34 UniRef50_UPI00006611F1 Cluster: Homolog of Homo sapiens "Solute ... 147 7e-34 UniRef50_UPI00015B5C87 Cluster: PREDICTED: similar to GA18750-PA... 146 1e-33 UniRef50_A4R7E6 Cluster: Transporter; n=1; Magnaporthe grisea|Re... 146 2e-33 UniRef50_UPI000023D6A8 Cluster: hypothetical protein FG04240.1; ... 145 4e-33 UniRef50_A5UNF8 Cluster: Na+-dependent transporter, SNF family; ... 144 5e-33 UniRef50_Q2NGG4 Cluster: Predicted Na+-dependent transporter; n=... 144 6e-33 UniRef50_UPI0000DB790B Cluster: PREDICTED: similar to CG5549-PA;... 143 1e-32 UniRef50_P44849 Cluster: Uncharacterized sodium-dependent transp... 143 1e-32 UniRef50_A7BDH7 Cluster: Putative uncharacterized protein; n=1; ... 141 4e-32 UniRef50_UPI0001556266 Cluster: PREDICTED: similar to Solute car... 140 8e-32 UniRef50_Q0PHT6 Cluster: High-affinity dopamine transporter prot... 138 5e-31 UniRef50_Q0PHU0 Cluster: High-affinity dopamine transporter prot... 137 7e-31 UniRef50_Q2NGB7 Cluster: Predicted Na+-dependent transporter; n=... 136 2e-30 UniRef50_A7RHB6 Cluster: Predicted protein; n=1; Nematostella ve... 135 4e-30 UniRef50_UPI0000E816B2 Cluster: PREDICTED: similar to solute car... 133 1e-29 UniRef50_Q0UQY0 Cluster: Transporter; n=1; Phaeosphaeria nodorum... 133 2e-29 UniRef50_Q9VLY3 Cluster: Transporter; n=6; Drosophila melanogast... 132 3e-29 UniRef50_A4RP68 Cluster: Transporter; n=2; Sordariomycetes|Rep: ... 131 5e-29 UniRef50_Q0G8L9 Cluster: High-affinity octopamine transporter pr... 129 2e-28 UniRef50_Q6F6P5 Cluster: Transporter; n=2; Acinetobacter|Rep: Tr... 128 4e-28 UniRef50_Q5ARW4 Cluster: Transporter; n=7; Pezizomycotina|Rep: T... 128 6e-28 UniRef50_UPI0000D66570 Cluster: PREDICTED: similar to orphan neu... 126 2e-27 UniRef50_O18300 Cluster: Transporter; n=1; Caenorhabditis elegan... 125 3e-27 UniRef50_Q4TJ95 Cluster: Transporter; n=1; Tetraodon nigroviridi... 124 5e-27 UniRef50_Q4SIS0 Cluster: Transporter; n=2; Tetraodontidae|Rep: T... 124 5e-27 UniRef50_A4VB21 Cluster: Transporter; n=1; Platynereis dumerilii... 124 1e-26 UniRef50_UPI0000EBDBFC Cluster: PREDICTED: similar to orphan neu... 122 3e-26 UniRef50_Q8IGR3 Cluster: Transporter; n=3; Drosophila melanogast... 120 9e-26 UniRef50_Q2VFP2 Cluster: GABA-a receptor 3-like protein; n=1; My... 119 3e-25 UniRef50_UPI000059FF44 Cluster: PREDICTED: similar to Orphan sod... 117 8e-25 UniRef50_Q4SNN3 Cluster: Transporter; n=1; Tetraodon nigroviridi... 117 1e-24 UniRef50_Q17EZ3 Cluster: Sodium/shloride dependent amino acid tr... 111 5e-23 UniRef50_A3CV46 Cluster: Transporter; n=1; Methanoculleus marisn... 109 2e-22 UniRef50_Q9GZN6 Cluster: Orphan sodium- and chloride-dependent n... 102 3e-20 UniRef50_UPI000059FF45 Cluster: PREDICTED: similar to solute car... 100 1e-19 UniRef50_O67854 Cluster: Transporter; n=1; Aquifex aeolicus|Rep:... 100 1e-19 UniRef50_UPI0000F2D4C7 Cluster: PREDICTED: hypothetical protein;... 100 2e-19 UniRef50_UPI0000E49EF2 Cluster: PREDICTED: similar to solute car... 100 2e-19 UniRef50_Q7NXF6 Cluster: Transporter; n=4; Bacteria|Rep: Transpo... 99 3e-19 UniRef50_UPI0000E4A5E3 Cluster: PREDICTED: similar to creatine t... 98 7e-19 UniRef50_A6NZ68 Cluster: Transporter; n=1; Bacteroides capillosu... 98 7e-19 UniRef50_Q2S448 Cluster: Sodium-and chloride-dependent transport... 97 1e-18 UniRef50_A7T6E6 Cluster: Predicted protein; n=1; Nematostella ve... 95 7e-18 UniRef50_Q8U3T4 Cluster: Putative transporter; n=1; Pyrococcus f... 94 9e-18 UniRef50_Q800X8 Cluster: GABA transporter GAT-3; n=9; Euteleosto... 93 2e-17 UniRef50_Q9X7H2 Cluster: Transporter; n=5; Neisseria|Rep: Transp... 93 2e-17 UniRef50_Q6AQ17 Cluster: Probable sodium-dependent transporter; ... 93 3e-17 UniRef50_Q2S4H8 Cluster: Sodium-and chloride-dependent transport... 92 5e-17 UniRef50_P45320 Cluster: Uncharacterized sodium-dependent transp... 92 5e-17 UniRef50_Q5WAS4 Cluster: SNF family sodium-dependent transporter... 91 6e-17 UniRef50_Q5DG59 Cluster: Transporter; n=1; Schistosoma japonicum... 91 8e-17 UniRef50_Q8TSA2 Cluster: Sodium/chloride-dependent transporter; ... 91 8e-17 UniRef50_Q9KDT3 Cluster: Sodium-dependent transporter; n=2; Bact... 90 1e-16 UniRef50_A6TKT9 Cluster: Transporter; n=2; Clostridiaceae|Rep: T... 90 2e-16 UniRef50_Q8F511 Cluster: Transporter; n=4; Leptospira|Rep: Trans... 89 3e-16 UniRef50_UPI0000D57368 Cluster: PREDICTED: similar to CG8485-PA,... 89 4e-16 UniRef50_A5ZSS6 Cluster: Transporter; n=5; Clostridiales|Rep: Tr... 89 4e-16 UniRef50_Q3V0K1 Cluster: Transporter; n=10; Eutheria|Rep: Transp... 88 8e-16 UniRef50_Q1MR94 Cluster: Probable sodium-dependent transporter; ... 87 1e-15 UniRef50_Q6GC30 Cluster: Transporter; n=16; Staphylococcus|Rep: ... 86 2e-15 UniRef50_A3HYF8 Cluster: Sodium-and chloride-dependent transport... 86 2e-15 UniRef50_Q9KG95 Cluster: Sodium-dependent transporter; n=34; Bac... 86 3e-15 UniRef50_Q8A1L9 Cluster: Na+-dependent transporter; n=8; Bactero... 85 4e-15 UniRef50_A7HNE0 Cluster: Sodium:neurotransmitter symporter; n=1;... 85 4e-15 UniRef50_UPI0000DB7B68 Cluster: PREDICTED: similar to CG8291-PA,... 85 5e-15 UniRef50_Q8D8U8 Cluster: Na+-dependent transporter of the SNF fa... 85 7e-15 UniRef50_Q81S42 Cluster: Sodium-dependent transporter; n=13; Bac... 85 7e-15 UniRef50_Q73R42 Cluster: Sodium-dependent transporter, putative;... 85 7e-15 UniRef50_UPI00015B5071 Cluster: PREDICTED: similar to sodium/chl... 84 9e-15 UniRef50_A4A5L0 Cluster: Sodium-and chloride-dependent transport... 84 9e-15 UniRef50_A7HET8 Cluster: Sodium:neurotransmitter symporter precu... 84 1e-14 UniRef50_A6PLC6 Cluster: Sodium:neurotransmitter symporter precu... 84 1e-14 UniRef50_Q5QY70 Cluster: Na+-dependent transporter of the SNF fa... 83 2e-14 UniRef50_Q3A7I2 Cluster: Na+-dependent transporters of the SNF f... 83 2e-14 UniRef50_A6GC50 Cluster: Probable sodium-dependent transporter; ... 83 2e-14 UniRef50_UPI00015563FA Cluster: PREDICTED: hypothetical protein,... 83 3e-14 UniRef50_Q1N557 Cluster: Sodium-dependent transporter, NSS famil... 82 4e-14 UniRef50_A3VN81 Cluster: Sodium-dependent transporter family pro... 82 4e-14 UniRef50_Q8MSR0 Cluster: Transporter; n=3; Sophophora|Rep: Trans... 82 5e-14 UniRef50_Q8RHM5 Cluster: Sodium-dependent tyrosine transporter; ... 81 7e-14 UniRef50_A6PRZ0 Cluster: Transporter; n=2; Bacteria|Rep: Transpo... 81 7e-14 UniRef50_A0RQG4 Cluster: Sodium-and chloride-dependent transport... 81 7e-14 UniRef50_Q9HPQ2 Cluster: Daunorubicin resistance ABC transporter... 81 7e-14 UniRef50_Q5QUN5 Cluster: Na+-dependent transporter of the SNF fa... 80 2e-13 UniRef50_Q7NPX3 Cluster: Transporter; n=5; Proteobacteria|Rep: T... 79 3e-13 UniRef50_Q4LEH9 Cluster: Sodium-dependent transporter; n=1; uncu... 79 3e-13 UniRef50_Q6MBR5 Cluster: Transporter; n=1; Candidatus Protochlam... 79 5e-13 UniRef50_Q3INN0 Cluster: Transporter 55; n=1; Natronomonas phara... 78 8e-13 UniRef50_A4BUI1 Cluster: Probable sodium-dependent transporter; ... 77 1e-12 UniRef50_Q1N1Z9 Cluster: Na+-dependent transporter of the SNF fa... 77 2e-12 UniRef50_Q6MLR2 Cluster: Sodium-dependent serine transporter; n=... 76 3e-12 UniRef50_O25240 Cluster: Sodium-and chloride-dependent transport... 76 3e-12 UniRef50_A6VX44 Cluster: Transporter; n=12; Gammaproteobacteria|... 76 3e-12 UniRef50_Q6I1C4 Cluster: Sodium-dependent transporter, putative;... 75 4e-12 UniRef50_Q0A4P9 Cluster: Transporter; n=1; Alkalilimnicola ehrli... 75 6e-12 UniRef50_Q8E9E5 Cluster: Sodium-dependent transporter, putative;... 75 8e-12 UniRef50_Q83A23 Cluster: Transporter; n=4; Coxiella burnetii|Rep... 74 1e-11 UniRef50_A1HTE8 Cluster: Transporter; n=1; Thermosinus carboxydi... 74 1e-11 UniRef50_Q892Y6 Cluster: Sodium dependent amino acid transporter... 73 2e-11 UniRef50_Q0IBN8 Cluster: Na+-dependent transporter of the SNF fa... 73 2e-11 UniRef50_A7HQJ6 Cluster: Sodium:neurotransmitter symporter precu... 73 2e-11 UniRef50_Q8DBI3 Cluster: Sodium-dependent transporter; n=50; Vib... 73 2e-11 UniRef50_A7CWE7 Cluster: Sodium:neurotransmitter symporter; n=1;... 73 2e-11 UniRef50_Q7M9R0 Cluster: Transporter; n=1; Wolinella succinogene... 72 4e-11 UniRef50_Q9JRT7 Cluster: Sodium-dependent transporter, putative;... 72 5e-11 UniRef50_UPI0000D56C34 Cluster: PREDICTED: similar to solute car... 71 7e-11 UniRef50_A5ZNA7 Cluster: Transporter; n=4; Bacteria|Rep: Transpo... 71 9e-11 UniRef50_A5ZA96 Cluster: Transporter; n=3; Clostridiales|Rep: Tr... 71 9e-11 UniRef50_A2BJD7 Cluster: Na+ dependent transporter; n=2; Desulfu... 71 9e-11 UniRef50_Q31G35 Cluster: Neurotransmitter: sodium symporter (NSS... 71 1e-10 UniRef50_A6FME6 Cluster: Sodium-dependent transporter family pro... 70 2e-10 UniRef50_Q9HPQ1 Cluster: Sodium-and chloride-dependent transport... 70 2e-10 UniRef50_Q4RXG4 Cluster: Transporter; n=2; Euteleostomi|Rep: Tra... 70 2e-10 UniRef50_Q1YQL0 Cluster: Sodium-and chloride-dependent transport... 70 2e-10 UniRef50_Q1QXG5 Cluster: Transporter; n=4; Gammaproteobacteria|R... 69 4e-10 UniRef50_Q1R0J6 Cluster: Transporter; n=2; Gammaproteobacteria|R... 69 5e-10 UniRef50_Q2NAX9 Cluster: Sodium-dependent transporter, NSS famil... 68 9e-10 UniRef50_UPI0000F1FDE3 Cluster: PREDICTED: hypothetical protein;... 67 1e-09 UniRef50_Q604C5 Cluster: Sodium-dependent transporter family pro... 67 1e-09 UniRef50_Q6Q8U6 Cluster: Predicted sodium-dependent transporter;... 67 1e-09 UniRef50_A6W2D9 Cluster: Transporter; n=2; Marinomonas|Rep: Tran... 67 2e-09 UniRef50_A7D6H7 Cluster: Sodium:neurotransmitter symporter; n=1;... 67 2e-09 UniRef50_A7GX85 Cluster: Transcriptional regulator, ModE family;... 66 2e-09 UniRef50_A0Q3N4 Cluster: Transporter; n=4; Clostridiales|Rep: Tr... 66 3e-09 UniRef50_UPI0000E46C11 Cluster: PREDICTED: similar to Na and Cl ... 65 5e-09 UniRef50_Q174T7 Cluster: Sodium/chloride dependent transporter; ... 65 5e-09 UniRef50_Q7VI00 Cluster: Transporter; n=6; Helicobacter|Rep: Tra... 65 6e-09 UniRef50_A1WCH2 Cluster: Transporter; n=9; Proteobacteria|Rep: T... 64 8e-09 UniRef50_Q5QZ24 Cluster: Na+-dependent transporter of the SNF fa... 64 1e-08 UniRef50_Q7VHS6 Cluster: Putative uncharacterized protein; n=1; ... 63 2e-08 UniRef50_A3UE60 Cluster: Sodium-dependent transporter, NSS famil... 63 2e-08 UniRef50_Q1FP51 Cluster: Transporter; n=1; Clostridium phytoferm... 63 3e-08 UniRef50_A6Q1D2 Cluster: Transporter; n=1; Nitratiruptor sp. SB1... 63 3e-08 UniRef50_A5Z8U1 Cluster: Transporter; n=4; Clostridiales|Rep: Tr... 63 3e-08 UniRef50_A0YHQ6 Cluster: Na+-dependent transporter of the SNF fa... 63 3e-08 UniRef50_A4BQ95 Cluster: Sodium-dependent transporter family pro... 62 3e-08 UniRef50_A6EYM5 Cluster: Transporter; n=1; Marinobacter algicola... 62 4e-08 UniRef50_A4J843 Cluster: Transporter; n=1; Desulfotomaculum redu... 61 8e-08 UniRef50_A1EXD4 Cluster: Sodium-dependent symporter family prote... 61 8e-08 UniRef50_Q29N15 Cluster: GA12537-PA; n=1; Drosophila pseudoobscu... 61 8e-08 UniRef50_O83067 Cluster: Sodium-and chloride-dependent transport... 60 2e-07 UniRef50_A5WGE1 Cluster: Transporter; n=5; Gammaproteobacteria|R... 60 2e-07 UniRef50_Q4RDW9 Cluster: Chromosome undetermined SCAF15483, whol... 58 7e-07 UniRef50_A5VFP7 Cluster: Transporter; n=1; Sphingomonas wittichi... 58 9e-07 UniRef50_Q5C106 Cluster: Transporter; n=2; Schistosoma japonicum... 58 9e-07 UniRef50_Q16RP7 Cluster: Sodium/chloride dependent transporter; ... 58 9e-07 UniRef50_Q0BY33 Cluster: Transporter; n=1; Hyphomonas neptunium ... 57 2e-06 UniRef50_A7BZ05 Cluster: Sodium-dependent transporter family pro... 56 2e-06 UniRef50_A5KBP9 Cluster: Amine transporter, putative; n=4; Plasm... 56 2e-06 UniRef50_Q4KIH8 Cluster: Sodium-and chloride-dependent transport... 56 3e-06 UniRef50_A1ZYB1 Cluster: Transporter; n=1; Microscilla marina AT... 56 3e-06 UniRef50_Q14LK2 Cluster: Hypothetical sodium-dependent transport... 55 5e-06 UniRef50_Q2SMN5 Cluster: Na+-dependent transporters of the SNF f... 54 9e-06 UniRef50_Q892Y5 Cluster: Sodium dependent amino acid transporter... 54 1e-05 UniRef50_A1U621 Cluster: Sodium:neurotransmitter symporter precu... 54 2e-05 UniRef50_UPI0000E490C2 Cluster: PREDICTED: similar to sodium/shl... 52 6e-05 UniRef50_UPI0000E47D5A Cluster: PREDICTED: similar to SJCHGC0254... 52 6e-05 UniRef50_Q8IQQ7 Cluster: Transporter; n=7; Diptera|Rep: Transpor... 51 1e-04 UniRef50_Q9V0L3 Cluster: Transporter; n=4; Thermococcaceae|Rep: ... 51 1e-04 UniRef50_Q4TAU1 Cluster: Transporter; n=1; Tetraodon nigroviridi... 50 2e-04 UniRef50_Q4VDZ5 Cluster: Glycerol dehydratase; n=1; Clostridium ... 50 2e-04 UniRef50_A7T318 Cluster: Predicted protein; n=2; Nematostella ve... 50 2e-04 UniRef50_Q60YU4 Cluster: Transporter; n=1; Caenorhabditis briggs... 48 6e-04 UniRef50_O01843 Cluster: Transporter; n=1; Caenorhabditis elegan... 48 6e-04 UniRef50_Q5C0C5 Cluster: SJCHGC08756 protein; n=2; Schistosoma j... 48 8e-04 UniRef50_Q14P41 Cluster: Hypothetical sodium-dependent transport... 48 0.001 UniRef50_A7S7Q6 Cluster: Predicted protein; n=1; Nematostella ve... 48 0.001 UniRef50_A4A5S2 Cluster: Sodium-and chloride-dependent transport... 46 0.002 UniRef50_Q4SNN4 Cluster: Chromosome 15 SCAF14542, whole genome s... 45 0.007 UniRef50_A2BQZ3 Cluster: Integral membrane protein, DUF6; n=5; P... 43 0.022 UniRef50_A7REU1 Cluster: Predicted protein; n=1; Nematostella ve... 43 0.029 UniRef50_Q4S9B0 Cluster: Transporter; n=1; Tetraodon nigroviridi... 42 0.066 UniRef50_Q61SF6 Cluster: Transporter; n=1; Caenorhabditis briggs... 42 0.066 UniRef50_Q9N4S2 Cluster: Putative uncharacterized protein; n=1; ... 40 0.15 UniRef50_A7AVP9 Cluster: Hypothetcial protein; n=1; Babesia bovi... 40 0.27 UniRef50_Q7P6C7 Cluster: Sodium-dependent tyrosine transporter; ... 39 0.35 UniRef50_Q4HES6 Cluster: Sodium-and chloride-dependent transport... 39 0.35 UniRef50_A4E957 Cluster: Putative uncharacterized protein; n=1; ... 39 0.47 UniRef50_Q7QFI0 Cluster: ENSANGP00000031294; n=2; Culicidae|Rep:... 38 0.62 UniRef50_Q8PZM2 Cluster: Putative uncharacterized protein; n=1; ... 37 1.4 UniRef50_Q5XDS6 Cluster: Branched-chain amino acid transport sys... 36 2.5 UniRef50_Q23KH0 Cluster: Putative uncharacterized protein; n=1; ... 36 2.5 UniRef50_Q5LMQ8 Cluster: Membrane protein, putative; n=1; Silici... 36 3.3 UniRef50_UPI00015B5B52 Cluster: PREDICTED: similar to glycosyltr... 36 4.3 UniRef50_UPI0000E48A3B Cluster: PREDICTED: similar to sodium/shl... 36 4.3 UniRef50_UPI0000E473C2 Cluster: PREDICTED: similar to LOC494867 ... 36 4.3 UniRef50_Q73QV1 Cluster: Integral membrane protein MviN; n=1; Tr... 36 4.3 UniRef50_Q4PNI2 Cluster: Putative uncharacterized protein; n=1; ... 36 4.3 UniRef50_A5WG93 Cluster: Cytochrome c oxidase, cbb3-type, subuni... 36 4.3 UniRef50_Q3IPT6 Cluster: Transporter 43; n=1; Natronomonas phara... 36 4.3 UniRef50_A6TKN8 Cluster: Putative transmembrane protein; n=1; Al... 35 5.7 UniRef50_Q2QV81 Cluster: PDR-like ABC transporter, putative, exp... 35 5.7 UniRef50_Q22970 Cluster: Putative uncharacterized protein F28A12... 35 5.7 UniRef50_Q6ANB0 Cluster: Probable amino acid ABC transporter, pe... 35 7.6 UniRef50_Q2B7Y0 Cluster: Putative uncharacterized protein; n=1; ... 35 7.6 UniRef50_Q1WVA3 Cluster: Type IV prepilin leader peptidase; n=1;... 35 7.6 UniRef50_Q1F0V4 Cluster: Na+/proline symporter-like; n=1; Clostr... 35 7.6 UniRef50_Q0CIN1 Cluster: Predicted protein; n=2; Aspergillus|Rep... 35 7.6 >UniRef50_Q9W1J0 Cluster: Transporter; n=10; Eumetazoa|Rep: Transporter - Drosophila melanogaster (Fruit fly) Length = 1201 Score = 932 bits (2306), Expect = 0.0 Identities = 438/606 (72%), Positives = 484/606 (79%), Gaps = 16/606 (2%) Query: 21 EIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLM 80 E E ERG WTGRFDF NVWRFPYLCYNNGGGAFLIPFT+MLVIAGLPLM Sbjct: 52 ESEHERGTWTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAFLIPFTIMLVIAGLPLM 111 Query: 81 FMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSS 140 FMELSFGQYAALGPVAVY +FCPLFRGLG GM++VS+IVMLYYNLIIAWTIFYM SF+ Sbjct: 112 FMELSFGQYAALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAWTIFYMFASFAP 171 Query: 141 IFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALR 200 + LPWQNC+ WSTK+C+SY +AD+CEA NGTYYLR C N + + +NIT LA AL+ Sbjct: 172 V---LPWQNCEPAWSTKYCFSYAQADQCEATNGTYYLRTCHNATSAAENNITTLALGALK 228 Query: 201 RPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTAL 260 RPPAEEYF N VLGLS GIEETG I+L +A CL AW IVFLCLCKGVQSSGKVVYFTAL Sbjct: 229 RPPAEEYFNNFVLGLSKGIEETGSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTAL 288 Query: 261 FPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLIT 320 FPYVVLVILF RGVTLPGA TGILFYLTPD+ QLANAQVWGDAAVQIFFALSPAWGGLIT Sbjct: 289 FPYVVLVILFVRGVTLPGASTGILFYLTPDWKQLANAQVWGDAAVQIFFALSPAWGGLIT 348 Query: 321 LSSYNKFSNNCYI-------------DSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVS 367 LSSYNKFSNNCY DSLIVA NIATSFFAGLVIFS+IGFLAHELNV Sbjct: 349 LSSYNKFSNNCYNCGTFELSTKSNSRDSLIVAFCNIATSFFAGLVIFSIIGFLAHELNVD 408 Query: 368 VDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRF 427 V++VVDQGAGLAFIVYPEVVTRLP+SP+W++LFFVMLLTLGLDSQFALMETVTTAILDRF Sbjct: 409 VEKVVDQGAGLAFIVYPEVVTRLPVSPVWAVLFFVMLLTLGLDSQFALMETVTTAILDRF 468 Query: 428 PNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWI 487 PN RQ K WVV VA+FGY+GGL FTTNSGMYWLQLMDKYAANWSVL+IAI ECILIAWI Sbjct: 469 PNLRQYKIWVVLSVAIFGYIGGLGFTTNSGMYWLQLMDKYAANWSVLLIAISECILIAWI 528 Query: 488 YGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPM 547 YG+++F DIQ MIG++S W + W MWR ITPA L+FIL FNW+EYKPA YGHYVYPM Sbjct: 529 YGSQRFLNDIQGMIGKRSWFWNFFWGIMWRYITPATLLFILFFNWVEYKPAKYGHYVYPM 588 Query: 548 WADAVGWTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWGQAGSTATCLST 607 WADAVGW +I P L+ ++ + L +PT EWG AG L Sbjct: 589 WADAVGWIVGLLPVLVIFLVAFQEIWRAPMSLSFRDRIKHLLQPTAEWGPAGRPCVNLHA 648 Query: 608 LRVETE 613 R +++ Sbjct: 649 ERYQSQ 654 >UniRef50_Q7QDY5 Cluster: Transporter; n=1; Anopheles gambiae str. PEST|Rep: Transporter - Anopheles gambiae str. PEST Length = 558 Score = 725 bits (1793), Expect = 0.0 Identities = 332/578 (57%), Positives = 415/578 (71%), Gaps = 26/578 (4%) Query: 18 LSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGL 77 +++E +RG+WTGR+DF NVWRFPYLCY+NGGGAFLIPFTVMLVIAGL Sbjct: 1 MNDEALAKRGSWTGRYDFLLSLLGYSVGLGNVWRFPYLCYSNGGGAFLIPFTVMLVIAGL 60 Query: 78 PLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVS 137 PLMFMELS QY LGP ++ + P+ G+GYGM++VS +VMLYYN+IIAWT+FYM VS Sbjct: 61 PLMFMELSLAQYVGLGPAILFKRLAPISEGIGYGMILVSGMVMLYYNVIIAWTVFYMVVS 120 Query: 138 FSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKT 197 F LPW+ C+ EW+T +C+SYEE D C A N +YY+ C ++ Sbjct: 121 FED---PLPWRGCQHEWATVNCFSYEEEDNCLATNRSYYMANCMSR-------------- 163 Query: 198 ALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYF 257 E + N L +S+GIEETG I +A+CLL AW IVFLCL +GV+SSGKVVYF Sbjct: 164 --------EQYRNYFLQISAGIEETGMINQRLAICLLVAWAIVFLCLSRGVKSSGKVVYF 215 Query: 258 TALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGG 317 TALFPYVVL LF RG+TLPGA GIL+Y+ PD+ +L AQ+WGDAAVQIFFALSPAWGG Sbjct: 216 TALFPYVVLAALFIRGLTLPGAYDGILYYVRPDWDKLRTAQIWGDAAVQIFFALSPAWGG 275 Query: 318 LITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAG 377 L+TL+SYN+F NNCY D+++VA+SNI TSFFAG VIF++IGFLAHEL+ SVD V+DQGAG Sbjct: 276 LLTLASYNRFDNNCYRDAIVVAISNILTSFFAGFVIFAIIGFLAHELDTSVDSVIDQGAG 335 Query: 378 LAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWV 437 LAF+V+PE+V +L + LWS+LFF MLLTLGLDSQF LMETV TA+LD FP R++K V Sbjct: 336 LAFVVFPELVGKLQMPRLWSVLFFFMLLTLGLDSQFTLMETVVTAVLDTFPALRRRKIAV 395 Query: 438 VFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDI 497 V V++ GYLGGLIF TNSGMYW QL DKYAANWSVL+IAI ECIL+ W+YG E+F +I Sbjct: 396 VAGVSIVGYLGGLIFVTNSGMYWFQLFDKYAANWSVLLIAIAECILVGWVYGCERFISNI 455 Query: 498 QRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGWTXX 557 + M+G++SK + W +W+ ITPA L+FIL FNW++YKP +YG Y+YP WAD GW Sbjct: 456 EEMLGKRSKWFHRFWVTVWKYITPAMLLFILCFNWLQYKPVAYGRYIYPNWADVFGWIIA 515 Query: 558 XXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEW 595 + + + R L +P+ EW Sbjct: 516 LAPFGIAVIVAVKNMSTSSSPFA-WQTIRKLLQPSSEW 552 >UniRef50_UPI0000586FC3 Cluster: PREDICTED: similar to IP14091p isoform 1; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to IP14091p isoform 1 - Strongylocentrotus purpuratus Length = 699 Score = 581 bits (1434), Expect = e-164 Identities = 283/552 (51%), Positives = 371/552 (67%), Gaps = 21/552 (3%) Query: 19 SEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLP 78 SEE++ ERGNWT DF NVWRFPYLCY+NGGGAFLIP+ VML +AG+P Sbjct: 39 SEEVD-ERGNWTNHLDFLLSCIGYAVGLGNVWRFPYLCYSNGGGAFLIPYLVMLCLAGVP 97 Query: 79 LMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSF 138 L F+EL+FGQY + GP+ +N PL RG+GYGMV+VS+IV +YYN+II +++FY SF Sbjct: 98 LFFLELAFGQYCSKGPIRAWNA-VPLMRGVGYGMVVVSAIVGIYYNVIITYSLFYFFKSF 156 Query: 139 SSIFYQLPWQNCKAEWSTKHCYSYE----EADECEAQNGTYY--------LRQCFNQSYS 186 + + LPW+ C W+TK C EAD +N T + +N +YS Sbjct: 157 ARV---LPWEGCHHAWNTKFCSQLVKECIEADGIVTENNTCVPIGNLTDAEMESYNVTYS 213 Query: 187 VSHNITALAK--TALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCL 244 NIT+ A R+ + E++ +L S I + G I + +CLL AW ++FLCL Sbjct: 214 DDGNITSYLDPLQASRQSASAEFYKYAMLNESGDIGDPGMISWQLTLCLLFAWSLMFLCL 273 Query: 245 CKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAA 304 KGV+SSGKVVYFTA FPYVVL ILF RG+TL G I GI F++TP + L +A+VW DAA Sbjct: 274 VKGVKSSGKVVYFTATFPYVVLFILFIRGITLEGQIDGIKFFITPQWHLLKDAKVWKDAA 333 Query: 305 VQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHEL 364 VQIF++LS +WGGLITLSSYNKF NNC+ D++IV ++N ATS FAG VIFS++G +AH L Sbjct: 334 VQIFYSLSASWGGLITLSSYNKFKNNCFRDAMIVPIANCATSIFAGFVIFSILGHMAHVL 393 Query: 365 NVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAIL 424 N V+ V+D+ GLAFI YPE VT LPISPLW+ILFF ML+TLG+DSQF ++ETVTTAI+ Sbjct: 394 NKPVESVIDEQFGLAFIAYPEAVTLLPISPLWAILFFFMLITLGMDSQFCIIETVTTAII 453 Query: 425 DRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILI 484 D FP+ R+KK VVF+ G++ GL T +G YW+ LMDKYAA++++LI + ECI I Sbjct: 454 DEFPSLRKKKHLVVFVYCFLGFIFGLSCVTQAGGYWVILMDKYAADFALLIFGLCECIGI 513 Query: 485 AWIYGAEKFCGDIQRMIGRQ--SKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGH 542 WIYGA +F DI+ M+G + W W ITP L+F+L FNW ++ + G Sbjct: 514 GWIYGARRFLNDIRTMLGDRIVDHPLFNFWPLTWCCITPGVLLFVLGFNWATWEFPTAGD 573 Query: 543 YVYPMWADAVGW 554 Y +P WA +GW Sbjct: 574 YEFPTWAHVIGW 585 >UniRef50_P48067 Cluster: Sodium- and chloride-dependent glycine transporter 1; n=60; Eukaryota|Rep: Sodium- and chloride-dependent glycine transporter 1 - Homo sapiens (Human) Length = 692 Score = 562 bits (1388), Expect = e-159 Identities = 270/576 (46%), Positives = 378/576 (65%), Gaps = 19/576 (3%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 +RGNW + +F NVWRFPYLCY NGGGAF+ P+ +ML+ G+PL FMEL Sbjct: 85 KRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMEL 144 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 SFGQ+A+ G + V+ + P+F+G+GYGM++VS+ + +YYN++I +Y FSS+ + Sbjct: 145 SFGQFASQGCLGVW-RISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYF---FSSMTHV 200 Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPA 204 LPW C W+T C +A NG+ N S+ ++H++ R P+ Sbjct: 201 LPWAYCNNPWNTHDCAGVLDASNLT--NGSRPAALPSNLSHLLNHSLQ-------RTSPS 251 Query: 205 EEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264 EEY+ VL LS I GE+RL + CL +W++VFLCL +GV+SSGKVVYFTA FPYV Sbjct: 252 EEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYV 311 Query: 265 VLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSY 324 VL ILF RGVTL GA GI++YLTP + ++ A+VWGDAA QIF++L+ AWGGLIT++SY Sbjct: 312 VLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLACAWGGLITMASY 371 Query: 325 NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYP 384 NKF NNCY DS+I++++N ATS +AG VIFS++GF+A+ L V V RV D G GLAF+ YP Sbjct: 372 NKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYP 431 Query: 385 EVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPN--FRQKKGWVVFIVA 442 E +T LPISPLWS+LFF ML+ LGL +QF L+ET+ TAI+D N QKK +V VA Sbjct: 432 EALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVA 491 Query: 443 VFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIG 502 V G+L G+ T+ +G+YWL LMD YAA++S+++I+ C+ I +IYG + DIQ M+G Sbjct: 492 VAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGHRNYFQDIQMMLG 551 Query: 503 RQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGWTXXXXXXX 562 L+ + WR ++PA + FILVF I+Y+P +Y HY YP WA A+G+ Sbjct: 552 FPPPLF---FQICWRFVSPAIIFFILVFTVIQYQPITYNHYQYPGWAVAIGFLMALSSVL 608 Query: 563 XXXXXXXDQICSGPDDLTIMEKARVLARPTEEWGQA 598 ++C D T++++ + +P+ +WG A Sbjct: 609 CIPLYAMFRLCRTDGD-TLLQRLKNATKPSRDWGPA 643 >UniRef50_UPI00005841AC Cluster: PREDICTED: similar to glycine transporter; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to glycine transporter - Strongylocentrotus purpuratus Length = 676 Score = 555 bits (1370), Expect = e-156 Identities = 278/586 (47%), Positives = 374/586 (63%), Gaps = 23/586 (3%) Query: 14 SKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLV 73 SK+ E+ ERGNW+ DF NVWRFPYLCY+NGGGAFLIP+ VML+ Sbjct: 61 SKSSKKEDENVERGNWSNHLDFILSCVSYAVGLGNVWRFPYLCYSNGGGAFLIPYIVMLL 120 Query: 74 IAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFY 133 AGLPL F+EL FGQY++ GP++ + PL +G+GYGMV VS+ V +YYN+II++T+FY Sbjct: 121 FAGLPLFFLELCFGQYSSSGPISAWRS-APLMKGVGYGMVAVSAWVAIYYNVIISYTMFY 179 Query: 134 MTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITA 193 M F S+ LPW C EW+T +C ++ ++ N T + + +VS + Sbjct: 180 M---FKSMTTSLPWIGCHHEWNTPYC-----SELIDSYNVTT------DGNATVSF-LDP 224 Query: 194 LAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGK 253 L + RR P+EEY+ + VL S + G I +A+CLL AW + F+ L KGV+SSGK Sbjct: 225 LQE--FRRRPSEEYYRHGVLHDSGDMGSFGYIIWPLALCLLLAWTLEFIFLAKGVKSSGK 282 Query: 254 VVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSP 313 VVYFTA+FPY+VL IL RG+TLPG + GILF++ P + L N +VW DAAVQIFF+LS Sbjct: 283 VVYFTAIFPYIVLFILLIRGMTLPGHMDGILFFIKPRWELLKNPKVWKDAAVQIFFSLSA 342 Query: 314 AWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVD 373 +WGGLITLSSYN+F NNC D+LIV + N ATS FAG VIFS++G++AHEL V VVD Sbjct: 343 SWGGLITLSSYNRFKNNCMRDALIVPLLNCATSIFAGFVIFSIMGYMAHELKKPVSEVVD 402 Query: 374 QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK 433 + GLAFI YPE V RLPISPLW+ LFF ML+TLGL SQ ++ETV T+I D F N R+K Sbjct: 403 EQFGLAFIAYPEAVARLPISPLWAFLFFFMLITLGLGSQLCIVETVVTSIADEF-NLRKK 461 Query: 434 KGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKF 493 K WV+ + + GLI T +G YW+ LMDKYAA++++LI + ECI + WIYG + F Sbjct: 462 KIWVLAAYCIIAFFMGLICVTQAGNYWVILMDKYAADFALLIFGMSECIGLGWIYGVKNF 521 Query: 494 CGDIQRMIGRQ--SKLWVYLWSAMWRIITPAALVFILVFNWIEYK-PASYGHYVYPMWAD 550 DI+ M+G + + W W +TPA L F+++F+WI ++ P + Y +P WA Sbjct: 522 TNDIRSMLGDRIVDNVLFNWWKLNWCFLTPAVLSFVMLFSWISWEPPMATETYPFPTWAH 581 Query: 551 AVGWTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWG 596 A+GW C D T ++ + +A P + WG Sbjct: 582 ALGWLLILTVIMWIPLYWIYAFCKAKGD-TFRQRLKAMATPEDSWG 626 >UniRef50_Q9Y345 Cluster: Sodium- and chloride-dependent glycine transporter 2; n=36; Eumetazoa|Rep: Sodium- and chloride-dependent glycine transporter 2 - Homo sapiens (Human) Length = 797 Score = 546 bits (1347), Expect = e-154 Identities = 268/580 (46%), Positives = 374/580 (64%), Gaps = 20/580 (3%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 RGNW+ + DF NVWRFPYL + NGGGAFLIP+ +ML +AGLP+ F+E+S Sbjct: 191 RGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVS 250 Query: 86 FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQL 145 GQ+A+ GPV+V+ K P +G G M+I+S ++ +YYN+II +T+FY+ SF S+ L Sbjct: 251 LGQFASQGPVSVW-KAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSV---L 306 Query: 146 PWQNCKAEWSTKHCYSYEEA--DECEAQNGTYYLRQCFNQSYSVSH--NITALAKTALRR 201 PW +C W+T C + D C + Q N ++ ++ N+T + T+ Sbjct: 307 PWGSCNNPWNTPECKDKTKLLLDSCVISDHPKI--QIKNSTFCMTAYPNVTMVNFTSQAN 364 Query: 202 PP----AEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYF 257 +EEYF VL +S+GIE GEIR +A+CL AWVIV+ L KG+++SGKVVYF Sbjct: 365 KTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLALCLFLAWVIVYASLAKGIKTSGKVVYF 424 Query: 258 TALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGG 317 TA FPYVVLVIL RGVTLPGA GI +++TP + +L +A VW DAA QIFF+LS AWGG Sbjct: 425 TATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGG 484 Query: 318 LITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAG 377 LITLSSYNKF NNCY D+LIV +N ATS FAG VIFSVIGF+A+E V+++ V DQG G Sbjct: 485 LITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPG 544 Query: 378 LAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNF-RQKKGW 436 +AF+VYPE +TRLP+SP W+I+FF+MLLTLGLD+ FA +ET+ T+I D FP + R K Sbjct: 545 IAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPV 604 Query: 437 VVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGD 496 + ++ G T G+Y QL+D YAA+++++IIAI E + I+++YG ++FC D Sbjct: 605 FTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCED 664 Query: 497 IQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGWTX 556 I+ MIG Q ++ W W +TP L FIL F++ +++P +YG Y YP W+ +GW Sbjct: 665 IEMMIGFQPNIF---WKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLM 721 Query: 557 XXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWG 596 ++ P +E+ +++ P +WG Sbjct: 722 LACSVIWIPIMFVIKMHLAPG--RFIERLKLVCSPQPDWG 759 >UniRef50_UPI0000E47D36 Cluster: PREDICTED: similar to glycine transporter 2; n=5; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to glycine transporter 2 - Strongylocentrotus purpuratus Length = 680 Score = 537 bits (1326), Expect = e-151 Identities = 269/600 (44%), Positives = 368/600 (61%), Gaps = 33/600 (5%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 ERGNW+ + DF NVWRFPYL Y NGGGAFLIP+ +ML AG+PL F+E+ Sbjct: 45 ERGNWSNKMDFVLSCLGYAVGLGNVWRFPYLAYRNGGGAFLIPYVIMLFFAGIPLFFLEV 104 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 S GQY +LGP+ + K PLFRG+GY ++ V +YYN+II +T++Y VSF+S Sbjct: 105 SLGQYCSLGPIRCW-KSVPLFRGIGYCQMVTVFYVGIYYNIIITYTVYYFGVSFTS---N 160 Query: 145 LPWQNCKAEWSTKHCY-SYEEADE-----CEAQNGTYYLRQCFNQS---YSVSHNITALA 195 LPW C W+TK+CY +Y + + + N +L Q+ + V+ N + Sbjct: 161 LPWVGCGNSWNTKYCYDNYRQCIDNTSIITDTNNTCVHLESLDEQTLNVFGVARNTSYDE 220 Query: 196 KTALR--------------RPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVF 241 A+R + +EEY+ VL S + +T I + +CL +W+IV+ Sbjct: 221 GEAMRYDLSNYTDPLQAERKLASEEYWKGAVLQESDSMNDTDGIIWQLLICLFVSWLIVY 280 Query: 242 LCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWG 301 LCL +G++SSGKVVYFTA FPYVVLVIL RG+TLPGA GI F++TPD S+L++A VW Sbjct: 281 LCLVRGIKSSGKVVYFTATFPYVVLVILLVRGLTLPGASEGIRFFVTPDLSKLSDAGVWQ 340 Query: 302 DAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLA 361 DAA+QIF++LS A GGL TL+SYNKF NNCY+DSL VA++N TS FAG VIFS++GF+A Sbjct: 341 DAAIQIFYSLSAAGGGLTTLASYNKFHNNCYVDSLFVAIANCCTSVFAGFVIFSIVGFMA 400 Query: 362 HELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTT 421 HEL V+ VV +G GLAF+ YP V R+PISPLWS+LFF ML+TLGLDSQFA+ME + T Sbjct: 401 HELQQPVETVVSEGFGLAFVAYPAAVARMPISPLWSVLFFGMLITLGLDSQFAIMENLVT 460 Query: 422 AILDRFP-NFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGE 480 I D FP R++K V+ + V + G T++G YW+ +D Y A ++ L+ A+ E Sbjct: 461 MICDEFPQTLRKRKNKVMLVACVSMFFLGFTCITHTGGYWVAHLDSYGAFFNYLVYALLE 520 Query: 481 CILIAWIYGAEKFCGDIQRMIGR--QSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPA 538 CI IAW YG ++F DI+ ++G WS W TP +VF+L FNW+++ Sbjct: 521 CIAIAWFYGIKRFTNDIRTIVGNGWVDNFTFNWWSVNWSAFTPGLMVFVLFFNWLQWVEP 580 Query: 539 SYGHYVYPMWADAVGWTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWGQA 598 SY + +P WA +GW + DL ++ R ++ PTEEWG A Sbjct: 581 SY-NGPFPTWAVIIGWLMTTMSLIWIPVVMIFEFLRADGDLA--QRWRAVSNPTEEWGPA 637 >UniRef50_UPI0000E49167 Cluster: PREDICTED: similar to solute carrier family 6 member 9; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to solute carrier family 6 member 9 - Strongylocentrotus purpuratus Length = 606 Score = 530 bits (1308), Expect = e-149 Identities = 249/543 (45%), Positives = 353/543 (65%), Gaps = 34/543 (6%) Query: 17 PLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAG 76 P ++E + RG W + DF NVWRFP+LCY NGGGAFLIP+ ++L AG Sbjct: 59 PYNDEEDQARGKWGSKIDFLLSCVSYAVGIGNVWRFPFLCYQNGGGAFLIPYILILFFAG 118 Query: 77 LPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTV 136 LPL +E+SFGQ+ +G + ++ K CP+F+G+GYGM+++ +V +YY +I+A+TIFY+ Sbjct: 119 LPLFLLEMSFGQFTGVGCLGIW-KICPMFKGIGYGMLVICFLVSIYYQVILAYTIFYLFS 177 Query: 137 SFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAK 196 S +SI LPW +C +W+T +C D + N T+ NI++L Sbjct: 178 SLTSI---LPWASCGHQWNTDNC-----TDRMQDSNSTF--------------NISSLLN 215 Query: 197 TALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVY 256 +PP+EEYF N VLG+S G+ + G ++ +A+CL+AAWVI FLCL KG+++SGKVVY Sbjct: 216 P---KPPSEEYFYNHVLGISDGVHDLGAVKWKLALCLMAAWVITFLCLIKGIKTSGKVVY 272 Query: 257 FTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWG 316 T+ FPY+VL ILF RGVTL GA+ GI+FY+ PD S+L QVW DAA QIFF+L A+G Sbjct: 273 LTSTFPYLVLFILFIRGVTLDGAVDGIIFYMKPDLSKLLTPQVWQDAATQIFFSLGVAFG 332 Query: 317 GLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGA 376 L TLSSYNK+ NNCY D+LIV+V N TS FAG VIFSV+GF+A + VSV+ + G Sbjct: 333 SLHTLSSYNKWKNNCYRDALIVSVINCLTSIFAGFVIFSVLGFMAKQAGVSVEDIATSGP 392 Query: 377 GLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRF----PNFRQ 432 GLAF+ YPE + ++PISPLWSILFF ML LGL SQF ETV T + D P FR+ Sbjct: 393 GLAFVAYPEAIAKMPISPLWSILFFTMLFMLGLGSQFCQFETVNTGLADELEKYSPKFRK 452 Query: 433 KKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEK 492 K + +++ +L GL GMY + LM+ ++ S++ I + E I+I W YG EK Sbjct: 453 YKWCITLTMSIVCFLLGLPLVCEGGMYLVNLMNDFSGGLSLVFIGMFETIVITWFYGVEK 512 Query: 493 FCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYG-HYVYPMWADA 551 + +++ M+G + + W A W+ ++P L+ +++F+ Y+P YG +Y+YP WA+A Sbjct: 513 YLDNLEAMLGFRLN---FFWKACWKFVSPVFLLVVIIFSLAMYEPKKYGANYIYPGWAEA 569 Query: 552 VGW 554 +GW Sbjct: 570 MGW 572 >UniRef50_Q99884 Cluster: Sodium-dependent proline transporter; n=19; Euteleostomi|Rep: Sodium-dependent proline transporter - Homo sapiens (Human) Length = 636 Score = 525 bits (1296), Expect = e-147 Identities = 263/617 (42%), Positives = 381/617 (61%), Gaps = 34/617 (5%) Query: 12 EKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVM 71 ++ L + RGNWTG+ DF NVWRFPY Y NGGGAFL+P+ +M Sbjct: 23 DQGDVDLDVDFAAHRGNWTGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFLM 82 Query: 72 LVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTI 131 L I G+PL F+ELS GQ+++LGP+AV+ K PLF+G G M+++ +V +YYN+IIA+ + Sbjct: 83 LAICGIPLFFLELSLGQFSSLGPLAVW-KISPLFKGAGAAMLLIVGLVAIYYNMIIAYVL 141 Query: 132 FYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNI 191 FY+ F+S+ LPW++C W+T+ C + + + NG L N+ Sbjct: 142 FYL---FASLTSDLPWEHCGNWWNTELCLEHRVSKD---GNGALPL------------NL 183 Query: 192 TALAKTALRRPPAEEYFTNQVLGL--SSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQ 249 T P+EEY++ VL + S GI GEIR + +CLL AWVIVFLC+ KGV+ Sbjct: 184 TCTVS------PSEEYWSRYVLHIQGSQGIGSPGEIRWNLCLCLLLAWVIVFLCILKGVK 237 Query: 250 SSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFF 309 SSGKVVYFTA FPY++L++L RGVTLPGA GI FYLTP F L +++VW +AA+QIF+ Sbjct: 238 SSGKVVYFTATFPYLILLMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEAALQIFY 297 Query: 310 ALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVD 369 +L +GGL+T +SYN F N Y D+ IV + N TS AG IFSV+G+++ EL V VD Sbjct: 298 SLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQELGVPVD 357 Query: 370 RVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPN 429 +V G GLAF+VYP+ +T LP+SP WS LFF MLLTLGLDSQFA +ET+ TA+ D FP Sbjct: 358 QVAKAGPGLAFVVYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEFPY 417 Query: 430 F-RQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIY 488 + R KK ++ V YL GLI TT+ GMYWL L+D Y+A++ ++++ I C+ + +Y Sbjct: 418 YLRPKKAVFSGLICVAMYLMGLILTTDGGMYWLVLLDDYSASFGLMVVVITTCLAVTRVY 477 Query: 489 GAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMW 548 G ++FC DI M+G + L+ + A W ++PA L+ +LV++ ++Y+P+ YG Y +P W Sbjct: 478 GIQRFCRDIHMMLGFKPGLY---FRACWLFLSPATLLALLVYSIVKYQPSEYGSYRFPPW 534 Query: 549 ADAVGWTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWGQA-GSTATCLST 607 A+ +G + ++ ++ E+ + +RP +WG + T + Sbjct: 535 AELLGILMGLLSCLMIPAGMLVAVLR--EEGSLWERLQQASRPAMDWGPSLEENRTGMYV 592 Query: 608 LRVETELSPPVLLLHGR 624 + SP L++H R Sbjct: 593 ATLAGSQSPKPLMVHMR 609 >UniRef50_Q9UN76 Cluster: Sodium- and chloride-dependent neutral and basic amino acid transporter B; n=21; Tetrapoda|Rep: Sodium- and chloride-dependent neutral and basic amino acid transporter B - Homo sapiens (Human) Length = 642 Score = 517 bits (1276), Expect = e-145 Identities = 251/538 (46%), Positives = 350/538 (65%), Gaps = 13/538 (2%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 +RGNW+ + D+ NVWRFPYL Y+NGGGAFLIP+ +ML +AGLPL F+E Sbjct: 35 DRGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLPLFFLEC 94 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 S GQ+A+LGPV+V+ + PLF+G+G MV++S V +YYN+IIA++++YM SF S + Sbjct: 95 SLGQFASLGPVSVW-RILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQS---E 150 Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCF--NQSYSVSHNITALAKTALRRP 202 LPW+NC + WS K+C C +++ N+S+ +N T + + + +P Sbjct: 151 LPWKNCSS-WSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGSEIYQP 209 Query: 203 ---PAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTA 259 P+E+Y+ L SSG+ ETG I +A+CLL AW+IV L KG++SSGKVVYFTA Sbjct: 210 GQLPSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTA 269 Query: 260 LFPYVVLVILFFRGVTLPGAITGILFYL--TPDFSQLANAQVWGDAAVQIFFALSPAWGG 317 LFPYVVL+IL RG TL GA GI +Y+ +F++L A+VW DAA QIF++LS AWGG Sbjct: 270 LFPYVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAWGG 329 Query: 318 LITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAG 377 L+ LSSYNKF NNC+ D+++V ++N TS FAG IFS++G +AH V +VV G Sbjct: 330 LVALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSGFD 389 Query: 378 LAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWV 437 LAFI YPE + +LP P WSILFF MLLTLGLDSQFA +ET+TT I D FP +K Sbjct: 390 LAFIAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPKVMKKMRVP 449 Query: 438 VFI-VAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGD 496 + + + +L GL+ T +G+YW+ L+D + A W +LI AI E + I WIYG +F D Sbjct: 450 ITLGCCLVLFLLGLVCVTQAGIYWVHLIDHFCAGWGILIAAILELVGIIWIYGGNRFIED 509 Query: 497 IQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGW 554 + MIG + ++ W A W +ITP L+ I +++ +++ +YG YP W A+GW Sbjct: 510 TEMMIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPNYGAIPYPDWGVALGW 567 >UniRef50_A7SXK0 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 594 Score = 510 bits (1258), Expect = e-143 Identities = 243/575 (42%), Positives = 346/575 (60%), Gaps = 16/575 (2%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 ER W + DF NVWRFPYLCY NGGGAFL+P+ +MLV+ G+P+ FMEL Sbjct: 5 ERETWGKKADFLLSCIGFAVGLGNVWRFPYLCYANGGGAFLLPYLIMLVLCGMPMFFMEL 64 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 S GQY +LGP+ V+ CPLFRG+G+ +++S +V +YYN+IIAW ++++ VSF S + Sbjct: 65 SAGQYFSLGPIGVWGAICPLFRGIGFASIVISFLVCVYYNVIIAWCLYFLAVSFRS---E 121 Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRR--- 201 + W++C W+T +CY+ + G+ N + + + + A A A Sbjct: 122 VLWKHCDNWWNTDNCYAGRIPESMSCSLGSGSNNSLVNSTLANATVLAANATNATTECLF 181 Query: 202 -----PPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVY 256 P+ E++ N +L LS GI E GEIR + +CL+ AWV V+ C+ KGV+SSGKVVY Sbjct: 182 PENQVSPSLEFWENYILRLSDGIGEAGEIRWQILVCLILAWVGVYFCMWKGVKSSGKVVY 241 Query: 257 FTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWG 316 FTA FPY+VL ILF RGVTLPGA GI FYL P++ +L + +VW AA QIF++L +G Sbjct: 242 FTATFPYLVLFILFVRGVTLPGADKGIAFYLKPEWHRLKDPKVWVAAATQIFYSLGIGFG 301 Query: 317 GLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGA 376 L+ + SYNKF NN + D++ +++ N TS FAG VIFS +GF++H LN ++ V + G Sbjct: 302 SLVAMGSYNKFHNNIFKDAISISLINCGTSVFAGFVIFSTLGFMSHVLNKPIEEVANSGP 361 Query: 377 GLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGW 436 GLAF+VYPE + ++PISPLW+ILFF M+LTLGLDSQF +ME V T I+D +P R++K Sbjct: 362 GLAFVVYPEAIAQMPISPLWAILFFFMILTLGLDSQFGMMEAVITGIIDEYPVCRKRKEL 421 Query: 437 VVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGD 496 + + +L G+ T G Y L L D + S+L + E + +AWIYGA++F D Sbjct: 422 FIAVACFLCFLLGITNVTQGGAYVLNLFDYQSGGVSLLFLGFFETVCLAWIYGADRFSKD 481 Query: 497 IQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGWTX 556 I+ M+G + W W W+ P + I ++ I ++ SYG Y YP WA+ GW Sbjct: 482 IEDMVGSRPAAW---WRFTWKFCAPTVMAGIFFYSIIFWQGVSYGSYKYPQWAEFFGWVI 538 Query: 557 XXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARP 591 I P T+ E+ L +P Sbjct: 539 ALSSMLFIPGNAIYMIWKTPG--TLRERVTFLLKP 571 >UniRef50_UPI00015B5244 Cluster: PREDICTED: similar to sodium/shloride dependent amino acid transporter, partial; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to sodium/shloride dependent amino acid transporter, partial - Nasonia vitripennis Length = 613 Score = 504 bits (1243), Expect = e-141 Identities = 240/574 (41%), Positives = 346/574 (60%), Gaps = 27/574 (4%) Query: 23 EPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFM 82 EPERG+W + +F NVWRFPYLCY NGGGAFL+P+ +ML++ G+PL FM Sbjct: 33 EPERGSWASKTEFLLSCAGYAIGIGNVWRFPYLCYRNGGGAFLVPYLLMLLLCGIPLFFM 92 Query: 83 ELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIF 142 E S GQ+ G + ++ + PLF+G G+ +VIV+ I +YYN+II++ + ++ +SF S Sbjct: 93 ESSMGQFGGTGCITMF-RMSPLFKGAGFAIVIVNVICTMYYNVIISYPLMFLVMSFKST- 150 Query: 143 YQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRP 202 LPW++C W+T C G + + +VS + +AKT + Sbjct: 151 --LPWESCDNPWNTYGCLKL---------GGEVFAEK------NVSDQMQLIAKT---KT 190 Query: 203 PAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFP 262 PA+E+F N +L +S I++ G I + +C L +W++VFLC+C GV++ GKVVYFTA FP Sbjct: 191 PADEFFHNHILKISDSIDDIGGIVWPLFICNLISWIVVFLCICNGVKTVGKVVYFTATFP 250 Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322 +++L +LF RGVTLPGA+ GILFY+ P + +L N +VW DAA+QIFF+L P WGG++ ++ Sbjct: 251 FLILFVLFVRGVTLPGAMDGILFYIMPKWDELLNLKVWADAAIQIFFSLGPGWGGIVNMA 310 Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIV 382 SYN F NN +DS++V + N TS FAG V+FSV+GF+A++ + V V G GLAF+ Sbjct: 311 SYNPFRNNNRLDSILVPILNCGTSIFAGFVVFSVLGFMAYKTGLPVSTVATGGPGLAFVT 370 Query: 383 YPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVA 442 YPE +T LP +W++LFF ML LG+DS F +E + +++ D +P+ R++K V F+ Sbjct: 371 YPEAITMLPFPQVWAVLFFFMLYLLGMDSCFVQIEAIISSVTDAYPHLRKRKSLVTFVSL 430 Query: 443 VFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIG 502 + +LG LIF TN GMY LQ+ D YAA+ SV+ I + E I++ W YG F D++ MIG Sbjct: 431 ILLFLGSLIFVTNGGMYILQMFDWYAASISVISICLVEVIVVGWTYGCGNFVRDVEFMIG 490 Query: 503 RQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGWTXXXXXXX 562 + W W W+ ITP L FI V I +Y YP WA AVGW Sbjct: 491 EKLHWW---WPLCWKYITPIILSFIFVTTIIFNTRLTYNGIDYPEWAVAVGWCSCLVSML 547 Query: 563 XXXXXXXDQICSGPDDLTIMEKARVLARPTEEWG 596 + T+ EK RPT +WG Sbjct: 548 CIPGYAIGYLIFAKG--TLREKLEYGTRPTHKWG 579 >UniRef50_UPI0000E47DA5 Cluster: PREDICTED: similar to solute carrier family 6 (neurotransmitter transporter, glycine), member 9; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to solute carrier family 6 (neurotransmitter transporter, glycine), member 9 - Strongylocentrotus purpuratus Length = 649 Score = 502 bits (1237), Expect = e-140 Identities = 235/583 (40%), Positives = 361/583 (61%), Gaps = 19/583 (3%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 +R +W+ + DF NVWRFPYLCY NGGGAFL+P+ +ML ++GLPL MEL Sbjct: 47 KREHWSNKMDFILSCLGWAVGLGNVWRFPYLCYRNGGGAFLVPYFLMLALSGLPLFLMEL 106 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 GQ+A+ G + ++ P F+G+G M +++S+V +YY +IIA+ +Y VSF+ + Sbjct: 107 GLGQFASRGVIQIWC-MAPAFKGIGLTMCMINSLVNIYYPVIIAYIFYYFFVSFAR---E 162 Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQ-NGTY-----YLRQCFNQSYSVSHNITALAKTA 198 LPW+ C W++++C + NGT+ Y ++ + + ++ A Sbjct: 163 LPWKYCNPLWASENCTDPDSRSNSNGTFNGTFNGTGEYDVSTWSMTTMLPNSTNATNAIE 222 Query: 199 LRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFT 258 + PA+E++ N VL SSG+ +TG IR + +CL W++ FL L KGV+S GKVVYFT Sbjct: 223 YAKRPAQEFWDNFVLQRSSGLHDTGVIRWQLLLCLALVWILTFLALVKGVKSVGKVVYFT 282 Query: 259 ALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGL 318 A FPY+VL IL RG+TL G++ GIL+Y+ P+FS+L + +VW DAA QIF++L P+WGGL Sbjct: 283 ATFPYIVLTILLIRGLTLEGSLDGILYYIRPNFSRLKDPRVWKDAAAQIFYSLGPSWGGL 342 Query: 319 ITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGL 378 +T++SYNKF+NN Y D +I+A+ N +TS FAG VIFSV+GF++ + + +D+V G GL Sbjct: 343 LTMASYNKFNNNFYRDGIIIALLNCSTSIFAGFVIFSVVGFMSFDSGLPIDKVATSGPGL 402 Query: 379 AFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILD----RFPNFRQKK 434 F+VYPE + R+P +PLWS+LFF M +T+GLDSQF +ETV + + D P R +K Sbjct: 403 VFVVYPEALARMPFAPLWSVLFFFMFITIGLDSQFVDVETVVSGLYDIVEENIPYMRGRK 462 Query: 435 GWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFC 494 + I++ +L G++ T SG+YWL L+D +A+ ++ L++A+ EC++I+++YGA +F Sbjct: 463 TLLTGIISFVTFLIGILLVTQSGIYWLTLIDNFASTFTTLVVAVSECLVISYVYGAGRFV 522 Query: 495 GDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASY-GHYVYPMWADAVG 553 D++ M+G ++ VY W W I P +VFI +F + Y+P Y Y YP W + +G Sbjct: 523 EDLKVMLG--YRIPVY-WQIAWMFIAPFVIVFIFIFFCVVYQPLIYDASYTYPQWGETLG 579 Query: 554 WTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWG 596 W + +I E+ P+E+WG Sbjct: 580 WLMALSAMIFIPGYFLFFFLFKTEG-SIRERFHTCLSPSEKWG 621 >UniRef50_Q7K4Y6 Cluster: GH22929p; n=8; Pancrustacea|Rep: GH22929p - Drosophila melanogaster (Fruit fly) Length = 631 Score = 495 bits (1222), Expect = e-138 Identities = 252/622 (40%), Positives = 365/622 (58%), Gaps = 32/622 (5%) Query: 9 GDEEKSKAPLSEE-----IEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGA 63 G KSK P + I ER W+G+ DF NVWRFPYLCY NGGGA Sbjct: 5 GHISKSKTPTPHDNDNNSISDERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGA 64 Query: 64 FLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYY 123 FL+P+ +MLV+ G+PL +MEL+ GQ+ G + + + PLF+G+GY +V+++ V YY Sbjct: 65 FLVPYGIMLVVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYY 124 Query: 124 NLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQN-GTYY-LRQCF 181 N+IIAW++ + SF++ LPW +C W+T +C +E + G Y L Sbjct: 125 NVIIAWSLRFFFASFTN---SLPWTSCNNIWNTPNCRPFESQNASRVPVIGNYSDLYAMG 181 Query: 182 NQS--YSVSH-NITALAKTALR-----RPPAEEYFTNQVLGL--SSGIEETGEIRLGMAM 231 NQS Y+ ++ N ++L +A+ + A EYF +L L S GI + G I+ MA+ Sbjct: 182 NQSLLYNETYMNGSSLDTSAVGHVEGFQSAASEYFNRYILELNRSEGIHDLGAIKWDMAL 241 Query: 232 CLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDF 291 CLL ++I + L KG+ +SGKVV+FTALFPY VL+IL RG+TLPG+ GI +YLTP+F Sbjct: 242 CLLIVYLICYFSLWKGISTSGKVVWFTALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNF 301 Query: 292 SQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGL 351 S + A+VW DAA Q+FF+L P +G L+ +SYNK+ NN Y D+L+ + N ATSF AG Sbjct: 302 SAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGF 361 Query: 352 VIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDS 411 VIFSV+G++AH L V ++ V +G GL F+VYP + +P S W+++FF+MLLTLGLDS Sbjct: 362 VIFSVLGYMAHTLGVRIEDVATEGPGLVFVVYPAAIATMPASTFWALIFFMMLLTLGLDS 421 Query: 412 QFALMETVTTAILDRFPNFRQKKGWVVFIVAVFG--YLGGLIFTTNSGMYWLQLMDKYAA 469 F E + TA+ D FP ++ + +F+ +F ++ GL T G Y+ L+D+YAA Sbjct: 422 SFGGSEAIITALSDEFPKIKRNR--ELFVAGLFSLYFVVGLASCTQGGFYFFHLLDRYAA 479 Query: 470 NWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILV 529 +S+L+ E I ++WIYG +F DI+ MIG + W WR + P L+FI V Sbjct: 480 GYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRY---WQVCWRFVAPIFLLFITV 536 Query: 530 FNWIEYKPASYGHYVYPMWADAVGWTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLA 589 + I Y+P +Y YVYP WA+A+GW ++ S P L ++ +L Sbjct: 537 YGLIGYEPLTYADYVYPSWANALGWCIAGSSVVMIPAVAIFKLLSTPGSL--RQRFTILT 594 Query: 590 RPTEEWGQAGSTATCLSTLRVE 611 P W S A L+ + E Sbjct: 595 TP---WRDQQSMAMVLNGVTTE 613 >UniRef50_Q6NND1 Cluster: Transporter; n=14; Endopterygota|Rep: Transporter - Drosophila melanogaster (Fruit fly) Length = 636 Score = 488 bits (1203), Expect = e-136 Identities = 240/534 (44%), Positives = 327/534 (61%), Gaps = 16/534 (2%) Query: 24 PERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFME 83 P+RG+W+ + DF NVWRFPYLCY NGGGAF++P+ + L +AG+P+ FME Sbjct: 56 PDRGSWSSKMDFILSVVGLAIGLGNVWRFPYLCYKNGGGAFILPYIITLFLAGIPMFFME 115 Query: 84 LSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFY 143 L+ GQ +G + V+ K P+F+G+GY ++S + +YY +I+AW +FY F S+ Sbjct: 116 LALGQMLTIGGLGVF-KIAPIFKGIGYAAAVMSCWMNVYYIVILAWAVFYF---FMSMRA 171 Query: 144 QLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSH-NITALAKTALRRP 202 +PW+ C W+T +C S E + + + SVS NIT+L T Sbjct: 172 DVPWRTCNNWWNTVNCVSQYERKNLHCWDKI--INGTTQKVCSVSALNITSLELTG---- 225 Query: 203 PAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFP 262 P +E++ + L +S GIEE G IR +A LL W++ + C+ KGV+ +GKVVYFTALFP Sbjct: 226 PVKEFWERRALQISHGIEEIGNIRWELAGTLLLVWILCYFCIWKGVKWTGKVVYFTALFP 285 Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322 YV+L IL RG+TLPGA+ GI FY+ P+FS+L N++VW DA QIFF+ G L+ L Sbjct: 286 YVLLTILLVRGITLPGALEGIKFYIIPNFSKLTNSEVWIDAVTQIFFSYGLGLGTLVALG 345 Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIV 382 SYNKF+NN Y D+LIV N +TS FAG VIFSVIGF+AHE V V G GLAF+V Sbjct: 346 SYNKFTNNVYKDALIVCTVNSSTSMFAGFVIFSVIGFMAHEQQRPVADVAASGPGLAFLV 405 Query: 383 YPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPN-FRQKKGWVVFIV 441 YP V +LP SP+WS LFF MLL +GLDSQF ME TAI+D +P R++K + IV Sbjct: 406 YPSAVLQLPGSPMWSCLFFFMLLLIGLDSQFCTMEGFITAIIDEWPQLLRKRKEIFIAIV 465 Query: 442 AVFGYLGGLIFTTNSGMYWLQLMDKYA-ANWSVLIIAIGECILIAWIYGAEKFCGDIQRM 500 YL GL T GMY Q++D YA + + +L + EC+ I+W YG ++F I+ M Sbjct: 466 CALSYLVGLTCITQGGMYIFQILDSYAVSGFCLLWLIFFECVSISWCYGVDRFYDGIKDM 525 Query: 501 IGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGW 554 IG +W W W + TPA + + FN +++ P Y Y YP WA A GW Sbjct: 526 IGYYPTVW---WKFCWCVTTPAICLGVFFFNIVQWTPVKYLDYSYPWWAHAFGW 576 >UniRef50_Q0X0E9 Cluster: Amino acid transporter; n=1; Crassostrea gigas|Rep: Amino acid transporter - Crassostrea gigas (Pacific oyster) (Crassostrea angulata) Length = 662 Score = 484 bits (1194), Expect = e-135 Identities = 236/557 (42%), Positives = 345/557 (61%), Gaps = 18/557 (3%) Query: 8 KGDEEKSKAPLSE-EIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLI 66 +GD+ ++ S +E +R W G+ +F NVWRFPYLCY NGGGAFLI Sbjct: 49 EGDDVSQRSTESSGSVEDDRAQWGGKLEFLLTCIGYAVGLGNVWRFPYLCYKNGGGAFLI 108 Query: 67 PFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLI 126 P+T+ML + GLPL +ME+ GQYA+LGP++++ + PLF+G+GY MVIVS ++ LYYN+I Sbjct: 109 PYTIMLALVGLPLFYMEVVLGQYASLGPISIW-RINPLFKGVGYAMVIVSWLIGLYYNVI 167 Query: 127 IAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYS 186 IA +FY+ SF+S +LPW++C EW+T C Y NGTY +N +Y Sbjct: 168 IAHVLFYLFASFTS---ELPWKHCNNEWNTPSCREYNYQPPSALGNGTYN-STAWNATYV 223 Query: 187 VS----HNIT--ALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIV 240 V+ HN T + +L P+EEY+ N VLG SSG++E G ++ +A+ LLA+WV V Sbjct: 224 VNTTFTHNSTYSPIIHHSLITTPSEEYYNNHVLGKSSGLDEIGGVQPYLALTLLASWVTV 283 Query: 241 FLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVW 300 +L L KG+QS GKVVYFTA+FPY++L++L FRGVTLPGA+ G+++YL PDF++L +VW Sbjct: 284 YLVLLKGIQSLGKVVYFTAIFPYLMLIVLMFRGVTLPGAVDGMIYYLKPDFNKLLEPRVW 343 Query: 301 GDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFL 360 DA QIF++LS GG+I +SSYNKF NNCY D++IV V N TS FAG V GF+ Sbjct: 344 SDACTQIFYSLSACSGGMIAMSSYNKFKNNCYKDAVIVCVINCGTSVFAGFVYSLYWGFM 403 Query: 361 AHELNVSVDRVVDQGAGLAFIV-YPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETV 419 A E NV V + ++ PE +TR+PI+ WSILFF+M+ TLG S+F+++E V Sbjct: 404 AQEKNVPVSGSCRWSSRFGLLLSIPEALTRMPIASFWSILFFIMMATLGFGSEFSIVECV 463 Query: 420 TTAILDRFPNFRQKKGWVVF--IVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIA 477 +A+ D FP + ++ ++F + +L GL G+Y L L+D + +LI+ Sbjct: 464 LSALTDVFPQIQPRRANIIFRSVFTAICFLLGLPMVCKGGIYLLNLVDFSVGGFPLLIVG 523 Query: 478 IGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKP 537 + E + I+WIYG +F +I M+G++ + W W+ ++ + ++ N I Y Sbjct: 524 LFELVAISWIYGYNRFSDNIFAMLGKRPTKY---WEICWKFVSLLVIGITVLMNIIMYTE 580 Query: 538 ASYGHYVYPMWADAVGW 554 Y WA ++GW Sbjct: 581 PELDGQTYSDWAKSLGW 597 >UniRef50_Q1ECY9 Cluster: Transporter; n=2; Danio rerio|Rep: Transporter - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 625 Score = 479 bits (1182), Expect = e-134 Identities = 250/604 (41%), Positives = 358/604 (59%), Gaps = 41/604 (6%) Query: 1 MMFQACLKGDEEKSKAPLSEEI-----EPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYL 55 ++F+ + +++K K+ +E + +RGNW+ + ++ NVWRFPYL Sbjct: 23 VLFKNSVGDEQDKDKSDKAEHVVQNDENSDRGNWSSKREYMLSMIGYAVGLGNVWRFPYL 82 Query: 56 CYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIV 115 Y +GGGAFLIP+T+ML ++GLPL FME SFGQ+ + GP+ V+ K P+ +G+G M++V Sbjct: 83 AYKHGGGAFLIPYTIMLAVSGLPLFFMESSFGQFCSQGPINVW-KAVPILQGVGITMMLV 141 Query: 116 SSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTY 175 S+ V +YYN+IIA++I+Y+ SF LPW S K+C + A N + Sbjct: 142 STFVAIYYNVIIAYSIYYLFASFQD---PLPW-------SIKNCNTTASNISTAAVNVS- 190 Query: 176 YLRQCFNQSYSVSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLA 235 Q QS S E+Y+ L SS ++ETG + +A+CLL Sbjct: 191 -CGQISGQSLS------------------EKYWDEVALQRSSSMDETGPVVWHLALCLLL 231 Query: 236 AWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYL--TPDFSQ 293 +W++V L KG++SSGKVVYFTA FPY+VL+IL RG TL GA GI FY+ + ++ Sbjct: 232 SWILVGAALFKGIKSSGKVVYFTATFPYIVLLILLIRGATLEGAKDGIEFYIGSQSNLTK 291 Query: 294 LANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVI 353 LA A+VW DAA QIFF+LS AWGGL+ LSSYNKF NNCY DS++V V+N TS FAG I Sbjct: 292 LAEAEVWKDAATQIFFSLSIAWGGLMALSSYNKFYNNCYQDSIVVCVTNCGTSIFAGFAI 351 Query: 354 FSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQF 413 FSV+G +AH V V D G LAFI YP+ +++LPISPLWSILFF ML+TLGLDSQF Sbjct: 352 FSVLGHMAHVYQRPVSEVADAGFALAFIAYPDALSKLPISPLWSILFFFMLITLGLDSQF 411 Query: 414 ALMETVTTAILDRFPN-FRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWS 472 A +E ++T +LD +P + K+G V V + +L GL T +G+YW+ L+D ++A W Sbjct: 412 AGIEVISTCLLDAYPEVLKSKRGLVTTAVCIILFLLGLPCVTRAGIYWVNLIDTFSAGWI 471 Query: 473 VLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNW 532 +L+ + E + + +YG +F DI+ MIG +S L+ W A W ITP L IL+++ Sbjct: 472 LLVAGLLEVLGLCILYGGNRFIKDIEMMIGTKSSLFWLWWRACWFFITPVVLSIILIWSL 531 Query: 533 IEYKPASYGHYVYPMWADAVGWTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPT 592 + +Y YP W ++GW ++C L ++ + PT Sbjct: 532 YTFTSPTYSSVAYPDWGISLGWCITAFSLMWIPIVAVWKVCKARGGL--WQRIKSACSPT 589 Query: 593 EEWG 596 E+WG Sbjct: 590 EDWG 593 >UniRef50_P48066 Cluster: Sodium- and chloride-dependent GABA transporter 3; n=182; cellular organisms|Rep: Sodium- and chloride-dependent GABA transporter 3 - Homo sapiens (Human) Length = 632 Score = 479 bits (1181), Expect = e-133 Identities = 230/535 (42%), Positives = 330/535 (61%), Gaps = 33/535 (6%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 ERG+W + +F NVWRFPYLCY NGGGAFLIP+ V + G+P+ F+E Sbjct: 49 ERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLET 108 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 + GQ+ + G + + K CPLF G+GY ++ + + +YY +I+AW IFY++ F++ + Sbjct: 109 ALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTT---E 165 Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPA 204 LPW C EW+T++C +++ + N S+ N T+ P Sbjct: 166 LPWATCGHEWNTENCVEFQKLNVS-------------NYSHVSLQNATS---------PV 203 Query: 205 EEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264 E++ ++VL +S GIE G +R +A+CLLAAW I + C+ KG +S+GKVVY TA FPY+ Sbjct: 204 MEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYI 263 Query: 265 VLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSY 324 +L+IL RGVTLPGA GI FYL PD S+L++ QVW DA QIFF+ + G L L SY Sbjct: 264 MLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSY 323 Query: 325 NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYP 384 N ++NNCY D +++ N TSF AG IFSV+GF+A+E V + V + G GLAFI YP Sbjct: 324 NNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYP 383 Query: 385 EVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPN-FRQ--KKGWVVFIV 441 + VT +P+SPLW+ LFF+ML+ LGLDSQF +E++ TA++D +P FR+ ++ ++ + Sbjct: 384 KAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILAL 443 Query: 442 AVFGYLGGLIFTTNSGMYWLQLMDKYAAN-WSVLIIAIGECILIAWIYGAEKFCGDIQRM 500 +V Y GL+ T GMY QL D YAA+ +L +AI ECI I W+YG+ +F +I+ M Sbjct: 444 SVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNRFYDNIEDM 503 Query: 501 IGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGH-YVYPMWADAVGW 554 IG + + W W I+TP I +F I+YKP Y + Y YP W +GW Sbjct: 504 IGYRPPSLI-KW--CWMIMTPGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGW 555 >UniRef50_P48029 Cluster: Sodium- and chloride-dependent creatine transporter 1; n=43; Euteleostomi|Rep: Sodium- and chloride-dependent creatine transporter 1 - Homo sapiens (Human) Length = 635 Score = 479 bits (1180), Expect = e-133 Identities = 234/536 (43%), Positives = 330/536 (61%), Gaps = 28/536 (5%) Query: 24 PERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFME 83 P R WT + DF NVWRFPYLCY NGGG FLIP+ ++ ++ G+P+ F+E Sbjct: 50 PPRETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLE 109 Query: 84 LSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFY 143 +S GQ+ G + V+N CPLF+GLGY +++ YY +++AW +Y+ SF++ Sbjct: 110 ISLGQFMKAGSINVWN-ICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTT-- 166 Query: 144 QLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPP 203 LPW C W+T C ++C N S + N+T + A RR P Sbjct: 167 -LPWATCGHTWNTPDCVEIFRHEDCA------------NASLA---NLTC-DQLADRRSP 209 Query: 204 AEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPY 263 E++ N+VL LS G+E G + + +CLLA WV+V+ C+ KGV+S+GK+VYFTA FPY Sbjct: 210 VIEFWENKVLRLSGGLEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPY 269 Query: 264 VVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSS 323 VVLV+L RGV LPGA+ GI++YL PD+S+L + QVW DA QIFF+ + G L L S Sbjct: 270 VVLVVLLVRGVLLPGALDGIIYYLKPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGS 329 Query: 324 YNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVY 383 YN+F+NNCY D++I+A+ N TSFFAG V+FS++GF+A E V + +V + G GLAFI Y Sbjct: 330 YNRFNNNCYKDAIILALINSGTSFFAGFVVFSILGFMAAEQGVHISKVAESGPGLAFIAY 389 Query: 384 PEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFP---NFRQKKGWVVFI 440 P VT +P++PLW+ LFF MLL LGLDSQF +E T +LD P FR ++ V + Sbjct: 390 PRAVTLMPVAPLWAALFFFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVAL 449 Query: 441 VAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLI-IAIGECILIAWIYGAEKFCGDIQR 499 ++ L T+ GMY QL D Y+A+ + L+ A EC+++AW+YGA++F DI Sbjct: 450 CCALCFVIDLSMVTDGGMYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDIAC 509 Query: 500 MIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGH-YVYPMWADAVGW 554 MIG + W+ W W TP + I +FN + Y+P Y + YVYP W +A+GW Sbjct: 510 MIGYRPCPWM-KW--CWSFFTPLVCMGIFIFNVVYYEPLVYNNTYVYPWWGEAMGW 562 >UniRef50_P31649 Cluster: Sodium- and chloride-dependent GABA transporter 3; n=8; Euarchontoglires|Rep: Sodium- and chloride-dependent GABA transporter 3 - Mus musculus (Mouse) Length = 602 Score = 472 bits (1164), Expect = e-131 Identities = 233/553 (42%), Positives = 333/553 (60%), Gaps = 39/553 (7%) Query: 11 EEKSKAPLSEEIEP----ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLI 66 E K P E++E ER +W + +F NVWRFPYLCY NGGGAF I Sbjct: 13 ETKPVCPAMEKVEEDGTLEREHWNNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFI 72 Query: 67 PFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLI 126 P+ + L G+P+ F+E + GQY G + + + CP+F G+GY ++ S++ +YY ++ Sbjct: 73 PYLIFLFTCGIPVFFLETALGQYTNQGGITAWRRICPIFEGIGYASQMIVSLLNVYYIVV 132 Query: 127 IAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYS 186 +AW +FY+ FSS LPW +C EW+T++C +++A++ Sbjct: 133 LAWALFYL---FSSFTTDLPWGSCSHEWNTENCVEFQKAND------------------- 170 Query: 187 VSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCK 246 S N+T+ T+ P E++ +VL LS GI+ G +R + +CLL AW+I + C+ K Sbjct: 171 -SMNVTSENATS----PVIEFWERRVLKLSDGIQHLGSLRWELVLCLLLAWIICYFCIWK 225 Query: 247 GVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQ 306 GV+S+GKVVYFTA FPY++LV+L RGVTLPGA GI FYL P+ ++L + QVW DA Q Sbjct: 226 GVKSTGKVVYFTATFPYLMLVVLLIRGVTLPGAAQGIQFYLYPNITRLWDPQVWMDAGTQ 285 Query: 307 IFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNV 366 IFF+ + G L L SYNK+ NNCY D + + + N +TSF AG IFS++GF++ E V Sbjct: 286 IFFSFAICLGCLTALGSYNKYHNNCYRDCIALCILNSSTSFMAGFAIFSILGFMSQEQGV 345 Query: 367 SVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDR 426 + V + G GLAFI YP V LP SPLW+ FF M++ LGLDSQF +E++ TA++D Sbjct: 346 PISEVAESGPGLAFIAYPRAVVMLPFSPLWACCFFFMVVLLGLDSQFVCVESLVTALVDM 405 Query: 427 FPN-FRQK--KGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAAN-WSVLIIAIGECI 482 +P FR+K + ++ IV+V + GLI T GMY QL D YAA+ +L +AI E + Sbjct: 406 YPRVFRKKNRREVLILIVSVISFFIGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFESL 465 Query: 483 LIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYG- 541 +AW+YGA +F +I+ MIG K W L W TPA + +F+ I+Y P +Y Sbjct: 466 CVAWVYGAGRFYDNIEDMIG--YKPWP-LIKYCWLFFTPAVCLATFLFSLIKYTPLTYNK 522 Query: 542 HYVYPMWADAVGW 554 Y YP W DA+GW Sbjct: 523 KYTYPWWGDALGW 535 >UniRef50_A7S977 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 605 Score = 467 bits (1151), Expect = e-130 Identities = 224/577 (38%), Positives = 345/577 (59%), Gaps = 27/577 (4%) Query: 21 EIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLM 80 E E R W+ + +F NVWRFPYLCY NGG FLIP+ +ML++ G+PL Sbjct: 34 EEEQTRDKWSSKAEFMLSSLGYCVGFGNVWRFPYLCYKNGGATFLIPYFIMLIVNGIPLF 93 Query: 81 FMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSS 140 F+EL+ GQ+ + G + V+ CPL +G+GY + ++S + +YY +I+AWT +Y+ +SF + Sbjct: 94 FLELAIGQWFSSGVIGVWKSICPLLKGIGYAICMISYLCCIYYIVILAWTFYYLFMSFQA 153 Query: 141 IFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALR 200 + +PW+ C W+TK C + D L C + N TA + Sbjct: 154 V---VPWKTCDNPWNTKFCRAKRSGD---------LLLNC--TELDLPQNCTAKPTS--- 196 Query: 201 RPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTAL 260 P+ E+++N VL ++ I + G++R + + +W++V+ CL KG++SSGKVVYFTA Sbjct: 197 --PSGEFWSNNVLEMTEDISDFGDMRWPLFGTFILSWIVVYFCLFKGIKSSGKVVYFTAT 254 Query: 261 FPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLIT 320 FP++VL IL RG TL G++ G+++YL PD+ +LA+ QVW AA QI+++L +G LIT Sbjct: 255 FPFIVLFILMIRGATLEGSLDGVIYYLNPDWERLADPQVWIYAATQIYWSLGVGFGALIT 314 Query: 321 LSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAF 380 SYNKF+NN + D+L+++++N +TSFFAG V+FSV+GF+A L+ +V +V G GLAF Sbjct: 315 FGSYNKFNNNVHKDALVISIANCSTSFFAGFVVFSVLGFMALTLDTTVAKVATSGPGLAF 374 Query: 381 IVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFP---NFRQKKGWV 437 + YPE ++++P+S LW++LFF ML+TLGLDSQFA +E V TAI+D +P + +K Sbjct: 375 VAYPEAISQMPVSTLWAVLFFFMLITLGLDSQFATIEAVITAIVDEYPWVRGTKWRKPVF 434 Query: 438 VFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDI 497 V I+ + + GL GM+ LMD A S+LI+A+ E I I WIYG ++F D+ Sbjct: 435 VLILCISLCILGLPCVFQGGMWIFNLMDYQVAGLSLLIVALLEIITIGWIYGVDRFSDDV 494 Query: 498 QRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGWTXX 557 + M GR+ W + W+ ++P + I++ N I++K Y YP WA+ +GW Sbjct: 495 EYMTGRRPMRW---FRICWKYVSPLCTLAIILANLIQWKGVKYNGKPYPGWAELIGWMLM 551 Query: 558 XXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEE 594 +I T+ E+ L +P EE Sbjct: 552 LSSVLMIPAFAIHEIYKRSG--TLRERITFLLKPDEE 586 >UniRef50_Q4SW66 Cluster: Transporter; n=2; Tetraodontidae|Rep: Transporter - Tetraodon nigroviridis (Green puffer) Length = 667 Score = 462 bits (1138), Expect = e-128 Identities = 230/546 (42%), Positives = 326/546 (59%), Gaps = 23/546 (4%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 ER WT + DF NVWRFPYLCY NGGG FLIP+ + + I G+P+ F+E+ Sbjct: 60 ERETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYLLFVFIGGIPVFFLEI 119 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 + GQ+ G V+ +N PLF+GLG +++ YY +I+ W ++++ SF++ Sbjct: 120 ALGQFMKQGGVSAWN-IAPLFKGLGLASMVIVFFCNTYYIMILVWGLYFLFHSFTN---P 175 Query: 145 LPWQNCKAEWSTKHC--------YSYEEADECEAQNGTYYLRQC--FNQSYSVSHNITAL 194 LPW C W+T++C ++ A A + L N S + S ++ Sbjct: 176 LPWATCGHPWNTQNCTQDFRRACHNRSAALSWSAVTPSSLLSSTSLVNLSSAQSFLNSSC 235 Query: 195 AKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKV 254 +T R P E++ +VL LS G+ E G I M +CL+A W+IV+ C+ KGV+S+GKV Sbjct: 236 TETEGLRSPVIEFWERKVLRLSGGLHELGNISYEMVLCLIATWIIVYFCMWKGVKSTGKV 295 Query: 255 VYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPA 314 VYFTALFPYV+LV+L G TLPGA+ GI++YL PD+S+L AQVW DA QIFF+ + Sbjct: 296 VYFTALFPYVILVVLLAHGATLPGALDGIIYYLKPDWSKLGEAQVWIDAGTQIFFSYAIG 355 Query: 315 WGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQ 374 G L L SYN+F NNCY D+ I+A+ N TSFFAG V+FSV+GF+A E V + +V + Sbjct: 356 LGALTALGSYNRFHNNCYRDAFILAIINSGTSFFAGFVVFSVLGFMATEQGVDISKVAES 415 Query: 375 GAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPN----F 430 G GLAFI YP+ VT +P++PLW+ LFF MLLTLGLDSQF +E + T I+D P Sbjct: 416 GPGLAFIAYPKAVTLMPLAPLWAALFFFMLLTLGLDSQFVGVEGLITGIMDMLPPKSVLG 475 Query: 431 RQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLI-IAIGECILIAWIYG 489 ++ V I + +L + T GMY QL D Y+A+ L+ A EC++IAW+YG Sbjct: 476 SLRREVVAAICCIICFLIDISMVTEGGMYVFQLFDYYSASGITLLWQAFWECVVIAWVYG 535 Query: 490 AEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGH-YVYPMW 548 A++F D+ RMIG ++ W ITP V + +F+ + +KP +Y Y YP W Sbjct: 536 ADRFMDDVARMIGYHPLPYM---KCCWSYITPLVCVGVFLFHVVNFKPLTYNTVYTYPWW 592 Query: 549 ADAVGW 554 + +GW Sbjct: 593 GEMLGW 598 >UniRef50_UPI0000E465AB Cluster: PREDICTED: similar to GABA neurotransmitter transporter; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to GABA neurotransmitter transporter - Strongylocentrotus purpuratus Length = 659 Score = 460 bits (1135), Expect = e-128 Identities = 242/610 (39%), Positives = 350/610 (57%), Gaps = 28/610 (4%) Query: 9 GDEEKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPF 68 GD EK E E ER W + DF NVWRFPYL + NGGGAFLIP+ Sbjct: 21 GDLEKKGEIEGENAEVEREGWDNKMDFIMICIGFAVGLGNVWRFPYLVFKNGGGAFLIPY 80 Query: 69 TVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIA 128 L+I+G+P+ F+E+S GQ +G ++V+ + P+ +G+G+ +++I+ YY +I A Sbjct: 81 LKSLIISGVPIFFLEISIGQALQVGGISVWEVY-PILKGVGFAGATIAAIMCTYYIVICA 139 Query: 129 WTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYE-EADE--CEAQNGTYYLRQCFNQSY 185 W+ FY+ FSS LPW +C W+ +C + D+ C A G + C S Sbjct: 140 WSFFYL---FSSFTTTLPWGDCDNSWNNLYCNDPALQGDDANCSAPTGFF----CTTNS- 191 Query: 186 SVSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLC 245 S+ N+T PA++++ + LG+S GI+E G +R + CL AWV+V+ C+ Sbjct: 192 SIYINLTE------GESPAQQFWEKRALGISDGIDEVGSLRWDLVGCLALAWVVVYFCIW 245 Query: 246 KGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAV 305 KGV+ +GK+V+FTAL PYV+L+ L RG+TLPGA GI FY+TPD+ +L + VW DAA Sbjct: 246 KGVKQTGKIVWFTALVPYVILLALLIRGLTLPGASEGIKFYVTPDWERLKSPTVWIDAAT 305 Query: 306 QIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELN 365 QIFF+ S G LI+L SYNK NN D+LIV V N TS FAG VIF+++GF+A + Sbjct: 306 QIFFSYSVGIGSLISLGSYNKVRNNAMFDTLIVGVVNAGTSLFAGFVIFAILGFMADQQG 365 Query: 366 VSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILD 425 V V VVD+G GL F+ YP V +P P WS++FF ML+ LGLDSQFA++E + T+++D Sbjct: 366 VPVKDVVDEGPGLTFVAYPTAVYYMPGGPAWSVIFFAMLIMLGLDSQFAILEGLVTSLMD 425 Query: 426 RFPNFRQKKGWVVFIVAV--FGYLGGLIFTTNSGMYWLQLMDKYAANWSVLI-IAIGECI 482 FP F ++ VF+V + +L GL+ T GMY+ QLMD Y A+ L+ +A ECI Sbjct: 426 EFPQFNLRQNRAVFLVIICFVDFLLGLLCVTEGGMYFFQLMDTYGASGMCLLWVAFWECI 485 Query: 483 LIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYG- 541 I++ YG +KF I +G + W W + PA + I +F+ I+Y+PA YG Sbjct: 486 AISYGYGIKKFYYIISDNMGFTPG---WYWPLCWAGLAPAVSLGIFLFSLIDYQPAKYGE 542 Query: 542 HYVYPMWADAVGWTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWGQAGST 601 +Y YP+W + +GW + P T ME+ ++ P + + G Sbjct: 543 NYYYPIWGEILGWMMAIVSMQWIPVYAIYVFLTTPG--TFMERLHIITSPRIQPAKPGKL 600 Query: 602 ATCLSTLRVE 611 ST+ VE Sbjct: 601 ED-ESTISVE 609 >UniRef50_UPI0000E48F61 Cluster: PREDICTED: similar to glycine transporter type 2b, partial; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to glycine transporter type 2b, partial - Strongylocentrotus purpuratus Length = 542 Score = 460 bits (1133), Expect = e-128 Identities = 214/540 (39%), Positives = 335/540 (62%), Gaps = 38/540 (7%) Query: 64 FLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYY 123 FLIP+ +ML +AG+PLMF+EL+FGQY GP+ ++ K CPLF G+G+ MV++S +V +YY Sbjct: 2 FLIPYFIMLFLAGMPLMFLELAFGQYGGEGPITIW-KACPLFAGIGWAMVMISGMVAIYY 60 Query: 124 NLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQ 183 N+I+AWT + SF+S ++PW+ C W+T D C+ + Sbjct: 61 NIIMAWTALFFVRSFTS---EVPWKTCNNTWNT---------DACQENSSV--------- 99 Query: 184 SYSVSHNITALAKTALRRPPAEEYFTNQVLGLSS-GIEETGEIRLGMAMCLLAAWVIVFL 242 + + NIT + PA+E++ N VL + +++ G ++ + MCLL +W+++F Sbjct: 100 AMEMGLNIT--------KRPAQEFYYNYVLDVDGHNLDDMGSMKWELVMCLLFSWIVIFC 151 Query: 243 CLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGD 302 C+CK V+SSGKVVYFTA FPY++L IL RGVTLPGA GI +YL+P + +L VWG Sbjct: 152 CICKSVKSSGKVVYFTATFPYIILTILLIRGVTLPGASIGIDYYLSPRWEKLKETAVWGA 211 Query: 303 AAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAH 362 AA QIF++L PAWGG++T SSYNKF+NNC ID++ + + N +SF+AG V+FS +GF+++ Sbjct: 212 AATQIFYSLGPAWGGVLTFSSYNKFNNNCLIDAICIPIINCLSSFYAGFVVFSTLGFMSY 271 Query: 363 ELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTA 422 + +S+D V +G GL F YPE ++++P +P WSILFF M +GLD+QF ++ETV + Sbjct: 272 KTGISIDNVAVKGPGLVFETYPEAISQMPAAPFWSILFFFMFFLVGLDTQFGMVETVVSG 331 Query: 423 ILDRFPNFRQKKGWV-VFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGEC 481 + D +PN +K G + +V V +L GL + G+Y +L++ Y+ S++++ + EC Sbjct: 332 LTDYYPNHLRKHGTLTALVVCVVFFLLGLPMASQGGIYMFELINWYSCWISLMLVGVFEC 391 Query: 482 ILIAWIYGAEKFCGDIQRMIGRQSKL------WVYLWSAMWRIITPAALVFILVFNWIEY 535 + +A+ YG +F DI+RMI + + +Y +S+ W +ITP+ +VFI VF + Y Sbjct: 392 VAVAYFYGVRRFTNDIRRMIADYTWMTPVVTPLLYWYSSCWLVITPSIIVFISVFGMVNY 451 Query: 536 KPASYGHYVYPMWADAVGWTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEW 595 P +G YVYP W++ +GW ++ + T ++ L RPT +W Sbjct: 452 VPVYFGDYVYPKWSEMLGWLMAVVPLFTIPLVMIIKLFFASEGETYAQRFMFLLRPTPQW 511 >UniRef50_Q8WPM9 Cluster: Similar to glycine transporter; n=1; Oikopleura dioica|Rep: Similar to glycine transporter - Oikopleura dioica (Tunicate) Length = 674 Score = 459 bits (1131), Expect = e-127 Identities = 220/536 (41%), Positives = 329/536 (61%), Gaps = 22/536 (4%) Query: 24 PERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFME 83 P R +W + +F N+WRFPYL Y NGGGAFLIP+ + LV+ GLP+ E Sbjct: 77 PGRQSWGNKIEFMLSMVGYAVGLGNIWRFPYLTYKNGGGAFLIPYLICLVLCGLPIFLFE 136 Query: 84 LSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFY 143 ++ GQ+ + GP+ +N P+F+G+GY MV VS+I+ YYN+II++T+ Y+ SF + Sbjct: 137 VALGQFCSQGPIKAFNGV-PIFKGIGYAMVAVSTIIGCYYNVIISYTLRYLFESFQAFST 195 Query: 144 -QLPWQNCKAEWSTKHCYSYEEADECEA--QNGTYYLRQCFNQSYSVSHNITALAKTALR 200 +LPW NC W+ + C + C + NGT + +++ R Sbjct: 196 GELPWANCDNSWNDEKCMDVGRLNRCRSIQANGTLEVPAMCQLNHTN------------R 243 Query: 201 RPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTAL 260 P+++YF N +L +S IE+ G + + + L ++ I+F+CL KG+QS+GK VY T+ Sbjct: 244 EAPSQQYFENHILEMSDSIEDVGLPKADLVLYLAISYAILFICLAKGIQSTGKAVYITST 303 Query: 261 FPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLIT 320 FPYVVL L G+T G++ GI ++LTP++ +L + VW DAA QIFF+LS +WGGLIT Sbjct: 304 FPYVVLTTLLIVGLTKDGSLNGIKYFLTPEWERLKDMSVWKDAATQIFFSLSASWGGLIT 363 Query: 321 LSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAF 380 L+SYN+F NN D+LIV ++N ATS FAGL IFS +GF+AH + V V+ V QG GLAF Sbjct: 364 LASYNEFDNNIVRDTLIVVLTNSATSIFAGLTIFSYLGFMAHSMGVEVEDVARQGPGLAF 423 Query: 381 IVYPEVVTRLPI-SPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVF 439 I YPE +T++ S +WS+LFF MLL LGL + FA M T+ T D FP R+++ Sbjct: 424 IAYPEALTQISTGSIVWSVLFFTMLLMLGLSTMFATMNTIITCCSDAFPQLRKRQASFTA 483 Query: 440 IVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQR 499 ++ VF +L G+ TT +G+Y L L D + ++++L+I++ E + I +IYG + FC DIQ Sbjct: 484 VLCVFLFLLGIPMTTRAGLYILTLFDDFGGSYALLVISVAEMVSICFIYGLDNFCSDIQI 543 Query: 500 MIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWAD--AVG 553 MI R ++ W W+ ++P L + + +K ++ G+YVYP W + AVG Sbjct: 544 MIKRPVGMF---WRICWKFVSPVLLTAVFIAVLANWKVSTLGNYVYPNWTNYPAVG 596 >UniRef50_P31641 Cluster: Sodium- and chloride-dependent taurine transporter; n=17; Gnathostomata|Rep: Sodium- and chloride-dependent taurine transporter - Homo sapiens (Human) Length = 620 Score = 457 bits (1127), Expect = e-127 Identities = 232/586 (39%), Positives = 330/586 (56%), Gaps = 34/586 (5%) Query: 24 PERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFME 83 P+R W+ + DF NVWRFPYLCY NGGGAFLIP+ + L +GLP+ F+E Sbjct: 39 PQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLE 98 Query: 84 LSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFY 143 + GQY + G + + K CPLF G+GY V++ S++ +YY +I+AW +Y+ SF Sbjct: 99 IIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQK--- 155 Query: 144 QLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPP 203 +LPW +C W+T HC + ++ SV I++ T+ P Sbjct: 156 ELPWAHCNHSWNTPHC-----------------MEDTMRKNKSVWITISSTNFTS----P 194 Query: 204 AEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPY 263 E++ VL LS GI+ G ++ +A+CLL W++ F C+ KGV+S+GKVVYFTA FP+ Sbjct: 195 VIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPF 254 Query: 264 VVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSS 323 +L++L RG+TLPGA GI FYL PD ++L + QVW DA QIFF+ + G + +L S Sbjct: 255 AMLLVLLVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGS 314 Query: 324 YNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVY 383 YNK+ N Y D +++ N TSF +G IFS++GF+A E V + V + G GLAFI Y Sbjct: 315 YNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAY 374 Query: 384 PEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGW--VVFI- 440 P+ VT +P+ WSILFF+MLL LGLDSQF +E T+++D +P+F +KG+ +FI Sbjct: 375 PKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSF-LRKGYRREIFIA 433 Query: 441 -VAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLI-IAIGECILIAWIYGAEKFCGDIQ 498 V YL GL T GMY QL D YAA+ L+ +A EC +IAWIYG + I+ Sbjct: 434 FVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIE 493 Query: 499 RMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGH-YVYPMWADAVGWTXX 557 MIG + W+ W +ITP V +F+ ++Y P +Y YVYP WA +GW+ Sbjct: 494 DMIGYRPGPWM---KYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLA 550 Query: 558 XXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWGQAGSTAT 603 ++C + K + R W AT Sbjct: 551 LSSMLCVPLVIVIRLCQTEGPFLVRVKYLLTPREPNRWAVEREGAT 596 >UniRef50_UPI00015B5724 Cluster: PREDICTED: similar to GABA neurotransmitter transporter-1B; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to GABA neurotransmitter transporter-1B - Nasonia vitripennis Length = 655 Score = 454 bits (1120), Expect = e-126 Identities = 217/537 (40%), Positives = 318/537 (59%), Gaps = 18/537 (3%) Query: 20 EEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPL 79 +E PERG+W + +F N+WRFPYLCY NGGGAF++P+ + L +AG+P+ Sbjct: 75 DEDIPERGSWGSKVEFILSVVGLAIGLGNLWRFPYLCYKNGGGAFMVPYFIALALAGVPM 134 Query: 80 MFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFS 139 MEL+ GQ +G + V+ K P+F+G+GY ++S +YY +I+AW +FY VS Sbjct: 135 FLMELALGQMMTIGGLGVF-KIAPIFKGIGYATCVLSCWTNIYYIIILAWALFYFLVSLR 193 Query: 140 SIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTAL 199 + +PW+ C+ W++K C + E + + +Y C ++SH L Sbjct: 194 A---DVPWRTCENSWNSKFCITPLERLKTSCWS-SYGDTVCQTSIGNLSHK--------L 241 Query: 200 RRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTA 259 + P +E++ + L +S GIE+ G IR +A L W++ + C+ KGV+ +GKVVYFTA Sbjct: 242 LKDPVKEFWERRTLQISDGIEDVGGIRWELAGTLAIVWIMCYFCIWKGVKWTGKVVYFTA 301 Query: 260 LFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLI 319 LFPY +LV+L RG+TLPGA+ G+ +Y TP+ S+L +VW DA QIFF+ + G L+ Sbjct: 302 LFPYCLLVVLLVRGLTLPGAMEGLKYYATPNLSKLGEPEVWIDAVTQIFFSYALGLGALV 361 Query: 320 TLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLA 379 L SYNKF+NN Y D+LIV N TS +G+VIFSV+GF+AHE V V G GLA Sbjct: 362 ALGSYNKFNNNVYKDALIVCTVNSCTSMLSGVVIFSVVGFMAHEQQKPVAEVAASGPGLA 421 Query: 380 FIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPN-FRQKKGWVV 438 F+VYP V ++P +P+WS LFF MLL +GLDSQF +E TA +D +P R++K + Sbjct: 422 FLVYPSAVLQMPGAPMWSCLFFFMLLLIGLDSQFCTVEGFITAAVDEWPRLLRKRKEIFI 481 Query: 439 FIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLI-IAIGECILIAWIYGAEKFCGDI 497 IV Y+ GL T GMY QL+D Y+ + VL+ + EC+ ++W +G +F I Sbjct: 482 AIVCFLSYIIGLSCITEGGMYVFQLLDSYSVSGFVLLFLMFFECVSVSWAFGVNRFYDGI 541 Query: 498 QRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGW 554 + MIG W W W + PA + + FN +++ P Y Y YP W+ +GW Sbjct: 542 RDMIGYYPCFW---WKICWTVTVPAICLGVFTFNVVKFSPVKYLDYEYPWWSHVLGW 595 >UniRef50_UPI0000D5722E Cluster: PREDICTED: similar to solute carrier family 6 (neurotransmitter transporter, glycine), member 5; n=1; Tribolium castaneum|Rep: PREDICTED: similar to solute carrier family 6 (neurotransmitter transporter, glycine), member 5 - Tribolium castaneum Length = 625 Score = 452 bits (1114), Expect = e-125 Identities = 217/554 (39%), Positives = 321/554 (57%), Gaps = 27/554 (4%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 ER W +F NVWRFPYLCY NGGGAFL+ + +M+ + G+PL +EL Sbjct: 10 ERSTWNKPLEFVLSCLGYAIGLGNVWRFPYLCYRNGGGAFLVTYIIMIFLMGMPLFLLEL 69 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 GQY+ LGP + PLF GLGY ++V +++ +YY +IIAWT+FY SF+ + Sbjct: 70 IVGQYSGLGPDQAFTNIAPLFTGLGYCTLVVITLITIYYMVIIAWTLFYFFASFTG---E 126 Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQ-------NGTYYLRQCF---------------N 182 L + +C +++T C ++ D+ Q N TYY +QC N Sbjct: 127 LGFGSCHNDFNTMECVKRQKVDDTLFQIEHSCPPNSTYYNKQCTLVDEICKSYNFEGASN 186 Query: 183 QSYSVSHNITALAKTALRRPPAE-EYFTNQVLGLSSGI-EETGEIRLGMAMCLLAAWVIV 240 +++ + T + R A EYF + VL ++ + G + + +CLL +W+I Sbjct: 187 RTFCYNSTSTVHISRVINRTLATYEYFRDYVLAINDSTWDNFGGLHWQLLLCLLLSWIIG 246 Query: 241 FLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVW 300 + C+ KGV++SGK VYFTALFPYV+L L +GV L GAI GIL YLTP + L VW Sbjct: 247 YFCVIKGVKTSGKAVYFTALFPYVILTALVVQGVILEGAIDGILLYLTPKWEMLLKVDVW 306 Query: 301 GDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFL 360 +AA Q F++ G L+TL+SYN F+NNC D+ IV +NI TS +AG IFS++GFL Sbjct: 307 ANAASQTFYSFGTGCGSLVTLASYNNFNNNCLKDTFIVTATNIFTSIYAGFAIFSMLGFL 366 Query: 361 AHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVT 420 AH++ V V+ V G GLAF+ YPE + RLP WS+ FF ML LGL SQFA +E + Sbjct: 367 AHQMGVPVEDVAQDGPGLAFVAYPEAILRLPAPTAWSLAFFFMLFILGLGSQFAGIEAIR 426 Query: 421 TAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGE 480 ILD++P R+ + ++ ++ +F ++ + N G+Y LM+ A+W++L+I +GE Sbjct: 427 CLILDKWPKLRKHEIYITLVICLFCFILAIPMCFNGGVYLFTLMEWNTASWAILLIGMGE 486 Query: 481 CILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASY 540 +++W YG KF ++ +M SK + W W +ITP L+ + +F PA+Y Sbjct: 487 VCVVSWCYGCNKFLDNMGQMEMVLSKPARWYWWICWVVITPLTLLGVFIFQMSNMTPATY 546 Query: 541 GHYVYPMWADAVGW 554 YV+P+WAD++GW Sbjct: 547 EDYVFPLWADSLGW 560 >UniRef50_Q8MZK8 Cluster: Na+/Cl-dependent neurotransmitter transporter-like protein; n=3; Schistosoma|Rep: Na+/Cl-dependent neurotransmitter transporter-like protein - Schistosoma mansoni (Blood fluke) Length = 761 Score = 452 bits (1113), Expect = e-125 Identities = 238/582 (40%), Positives = 338/582 (58%), Gaps = 49/582 (8%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 ERG W G+ +F NVWRFPYLC+ NGGGAFLIP+T+ML + GLPL F+E Sbjct: 56 ERGGWNGKLEFMMTCIGYAVGLGNVWRFPYLCFKNGGGAFLIPYTLMLALLGLPLFFLEF 115 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 +FGQ+A+LGP++V+N PLF+G+GY MV +S ++ +YY +++A ++Y VSF+ + Sbjct: 116 AFGQFASLGPISVWN-ISPLFKGIGYAMVFLSWLLNIYYQVVVAHCLYYFGVSFT---HT 171 Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPA 204 LPW C WST C +YS NIT + P+ Sbjct: 172 LPWTECNPAWSTPDCIDSNR------------------MNYS---NIT------YPKSPS 204 Query: 205 EEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264 E+Y+ NQVL LS G EE G +++CLL+ W++ L + KGVQS GKV YFT++FPY+ Sbjct: 205 EDYYFNQVLKLSPGFEEFGAPGWELSLCLLSCWILCGLAVIKGVQSLGKVSYFTSVFPYI 264 Query: 265 VLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSY 324 +L IL RG LPG+ G+L+YLTPDFS+L + QVW DAA QIFF+L GGLIT+SSY Sbjct: 265 MLTILLIRGALLPGSGAGVLYYLTPDFSRLTDPQVWADAATQIFFSLGCCNGGLITVSSY 324 Query: 325 NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYP 384 NKF NNC D++IVA+ N ATS +AG VIFS +GF+A++ N ++ V G GLAFIVYP Sbjct: 325 NKFKNNCCRDAVIVAIINCATSVYAGFVIFSNLGFMAYQKNTTIVEVASSGPGLAFIVYP 384 Query: 385 EVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNF---RQKKGWVVFIV 441 E +T +P+S LWS+LFF M+LTLG SQF+++ET + I D F ++ +VF + Sbjct: 385 EAMTNMPLSSLWSVLFFTMMLTLGFGSQFSILETTLSGIQDEFRRLGVHLTERRKIVFRI 444 Query: 442 AV--FGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQR 499 +V + GL G Y + + D + ++ LI+A+ E ++I ++YG ++F DI+ Sbjct: 445 SVCCLNFFMGLPMVCAGGYYLVTIYDSVMSGYAPLIVALSETVVITYVYGLKQFRCDIEL 504 Query: 500 MIGRQSKLWVYLWSAMWRIITPA---ALVFILVFNWIEYKPASYGHYVYPMWADAVGWTX 556 MI + + W W + TP L+ ++ N IE K +Y +P W + Sbjct: 505 MINERPN---WYWRICWLVFTPTICLLLIISVLTNRIELKEMNYS---FPPWTYVLYHLL 558 Query: 557 XXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWGQA 598 + CS L + E +P EWG A Sbjct: 559 SAGTVLLIVGWFIYKYCSEGGFLLLKE----FLKPVHEWGPA 596 >UniRef50_Q20C86 Cluster: Transporter; n=1; Drosophila virilis|Rep: Transporter - Drosophila virilis (Fruit fly) Length = 606 Score = 449 bits (1106), Expect = e-124 Identities = 231/548 (42%), Positives = 324/548 (59%), Gaps = 38/548 (6%) Query: 32 RFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAA 91 + DF NVWRFPYLCY NGGGAF++P+ + L +AG+P+ FMEL+ GQ Sbjct: 13 KLDFILSVVGLAIGLGNVWRFPYLCYKNGGGAFILPYILTLFLAGIPMFFMELALGQMLT 72 Query: 92 LGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCK 151 +G + V+ K P+F+G+GY ++S + +YY +I+AW +FY F S+ +PW+ C Sbjct: 73 IGGLGVF-KIAPIFKGIGYAAAVMSCWMNVYYIVILAWAVFYF---FMSMRADVPWRTCN 128 Query: 152 AEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSH-NITALAKTALRRPPAEEYFTN 210 W+T +C + E + + N+ SV+ NI++ T P +E++ Sbjct: 129 NWWNTINCVNQYERKNLHCWDKM--INGTANKVCSVAAANISSTELT----DPVKEFWER 182 Query: 211 QVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILF 270 + L +SSGI+E G IR +A LL W++ + C+ KGV+ +GKVVYFTALFPYV+L +L Sbjct: 183 RALQISSGIDEIGNIRWELAGTLLLVWILCYFCIWKGVKWTGKVVYFTALFPYVLLTVLL 242 Query: 271 FRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNN 330 RG+TLPGA+ GI FY+ P+FS+L++++VW DA QIFF+ G L+ L SYNKF+NN Sbjct: 243 IRGITLPGALEGIKFYIIPNFSKLSHSEVWIDAVTQIFFSYGLGLGTLVALGSYNKFTNN 302 Query: 331 CYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGA-------------- 376 Y D+LIV N +TS FAG VIFSVIGF+AHE V V G+ Sbjct: 303 VYKDALIVCTVNSSTSMFAGFVIFSVIGFMAHEQQRPVAEVAASGSYSAIQKYIYQKYIL 362 Query: 377 --------GLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFP 428 GLAF+VYP V +LP SP+WS LFF MLL +GLDSQF ME TAI+D +P Sbjct: 363 IMQNIKSPGLAFLVYPSAVLQLPGSPMWSCLFFFMLLLIGLDSQFCTMEGFITAIIDEWP 422 Query: 429 N-FRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYA-ANWSVLIIAIGECILIAW 486 R++K + IV + YL GL T GMY Q++D YA + + +L + EC+ I+W Sbjct: 423 QLLRKRKEIFIAIVCMLSYLVGLTCITQGGMYIFQILDSYAVSGFCLLWLIFFECVSISW 482 Query: 487 IYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYP 546 YG ++F I+ MIG +W W W + TPA + + FN +++ P Y Y YP Sbjct: 483 CYGVDRFYDGIKDMIGYYPTVW---WKFCWCVTTPAICLGVFFFNIVQWTPIKYLDYSYP 539 Query: 547 MWADAVGW 554 WA A GW Sbjct: 540 WWAHAFGW 547 >UniRef50_UPI0000587A15 Cluster: PREDICTED: similar to amino acid transporter B0+ isoform 1; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to amino acid transporter B0+ isoform 1 - Strongylocentrotus purpuratus Length = 773 Score = 446 bits (1098), Expect = e-123 Identities = 224/549 (40%), Positives = 328/549 (59%), Gaps = 24/549 (4%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 R W D+ NVWRFPYLCY NGGGAFL+P+T+ML+ AGLPL FME++ Sbjct: 53 RETWGSELDYVLSSMGLAIGLGNVWRFPYLCYQNGGGAFLLPYTLMLLFAGLPLYFMEVA 112 Query: 86 FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQL 145 GQY + G + V+ P+ RGLGYG + +S V ++YN+++A+ +++ SF+S +L Sbjct: 113 LGQYCSSGLIKVWRAVPPM-RGLGYGQLFMSVYVSIFYNVVLAYCLYFFFASFTS---RL 168 Query: 146 PWQNCKAEWSTKHCYS-YEEADE---CEAQNGTYYLRQCFNQSYSVSHNITALAK----- 196 PW C W+T+ C YEE E + NQ +N+T + + Sbjct: 169 PWIGCSNSWNTRLCSEIYEECIEDGGIVTDDKNCTRLDDLNQDELTYYNVTIIPRNGTYN 228 Query: 197 TALRRP--------PAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGV 248 T+L R P++EY+ N+VL SS + ETG + + +CLL AWV++FLCL KGV Sbjct: 229 TSLYRDPFIHVRALPSQEYWKNEVLQESSSMNETGTLVWKLTLCLLLAWVLIFLCLIKGV 288 Query: 249 QSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIF 308 +S+GKVVYFTA FP+VV+ IL R TL G G+ +Y+ P++ +L +A +W DAAVQIF Sbjct: 289 KSAGKVVYFTATFPFVVIFILLIRAATLEGHEEGVRYYIYPEWERLKHAVIWRDAAVQIF 348 Query: 309 FALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSV 368 F+L GGL+TL+SYNKF +NCY +S+ VAV N TSF +G +IFS++G++AH+LN SV Sbjct: 349 FSLGAGGGGLLTLASYNKFHSNCYRNSVFVAVVNCLTSFISGFMIFSIVGYMAHKLNKSV 408 Query: 369 DRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFP 428 G GL F+ PE + + P +P WS++FF ML+ L +DSQF +E + T ++D FP Sbjct: 409 KDFAHDGFGLVFVACPEALAKFPGAPFWSLMFFFMLILLAVDSQFVGVEVIVTVLIDEFP 468 Query: 429 N-FRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWI 487 + R ++ V I ++ GL TN+G YW+ L + YA ++ L+ I I++I Sbjct: 469 DILRPRRTLVTGIACFVMFILGLPIVTNAGGYWMALYNNYAVSFVPLVAGILLTCNISYI 528 Query: 488 YGAEKFCGDIQRMIG-RQSKLW-VYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVY 545 YG +F DI+ MIG R W + W W + TP L +L+ +W + +Y + Sbjct: 529 YGFRRFLDDIRVMIGTRIVDHWHFWFWLGNWLVATPLLLGIVLICHWAFDEAPTYNGMAF 588 Query: 546 PMWADAVGW 554 P WA A+G+ Sbjct: 589 PGWATAIGY 597 >UniRef50_A7S7X6 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 570 Score = 444 bits (1094), Expect = e-123 Identities = 208/549 (37%), Positives = 325/549 (59%), Gaps = 42/549 (7%) Query: 7 LKGDEEKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLI 66 LK DE+K + R W + +F N WRFPY+C+ NGGGAFLI Sbjct: 9 LKNDEKKDLVTVES-----RERWDRKIEFLFACIGFAVGYGNFWRFPYMCFKNGGGAFLI 63 Query: 67 PFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLI 126 P+ + L + G+PL FMELS GQ GP+ + K CPLF G+G+ +++S IV +YYN+I Sbjct: 64 PYVLFLCLGGIPLFFMELSLGQLLQEGPIKAWQKICPLFSGIGFASIVISFIVSIYYNVI 123 Query: 127 IAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYS 186 +AW+++++ ++S F +PW C W+T CY Y+ Sbjct: 124 LAWSLYFL---YNSFFADIPWVGCHHSWNTPDCYV-----------------------YN 157 Query: 187 VSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCK 246 S N + ++ + E+ VL ++ IEE G + + + +CLL AW++V+ + + Sbjct: 158 ASANASGVSSS-------REFLVKNVLEITKSIEEPGGLSVHLTLCLLVAWILVYFSIWR 210 Query: 247 GVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQ 306 G++++GKVVY TA PY++LVI F +GVTLPGAI G+L+++TP + +L + +VW DAA Q Sbjct: 211 GIRTTGKVVYVTATLPYIILVIFFIKGVTLPGAIDGVLYFITPQWDRLQDPKVWIDAASQ 270 Query: 307 IFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNV 366 I ++L+ +G LI +SYN NN + D+L+++V N ATS FAG VIF+++G++AH Sbjct: 271 ILYSLTIGFGVLIGFASYNPRKNNVFSDALLISVINCATSVFAGFVIFAIVGYMAHVQEK 330 Query: 367 SVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDR 426 SV V QG GL FIVYP +++LP +W+++FF+ML+ LGLDSQF +E V A++++ Sbjct: 331 SVPEVASQGPGLVFIVYPAAISQLPFPQIWAVIFFLMLIALGLDSQFGQVEVVAAALIEQ 390 Query: 427 FP-NFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIA 485 +P + + VV ++ +L GL + GM+ L D ++ S+L + E ++I Sbjct: 391 WPRQLHKHRELVVLVICFVMFLLGLSCVSKGGMFVFNLFDSFSCGLSLLFVVCFELLVIG 450 Query: 486 WIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVY 545 WIYGA ++ +I +MIGR W W W+ I+P ++ I VF+ +YK +Y + Y Sbjct: 451 WIYGARRYADNISQMIGRPVLQW---WVICWKYISPIMVLGIFVFSLAKYKRITYENVPY 507 Query: 546 PMWADAVGW 554 P WA+ VGW Sbjct: 508 PAWAEGVGW 516 >UniRef50_UPI000051A316 Cluster: PREDICTED: similar to CG1732-PA, isoform A; n=2; Endopterygota|Rep: PREDICTED: similar to CG1732-PA, isoform A - Apis mellifera Length = 620 Score = 443 bits (1091), Expect = e-123 Identities = 216/538 (40%), Positives = 317/538 (58%), Gaps = 17/538 (3%) Query: 19 SEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLP 78 + E + ERG W + DF NVWRFPYLCY NGGGAFLI + + +V G+P Sbjct: 58 NREEDTERGGWDNKLDFLFSCISVSVGLGNVWRFPYLCYKNGGGAFLITYGIAMVFCGIP 117 Query: 79 LMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSF 138 + F E++ GQY G + + + CPL +G+GY + + + +YY +IIAWT+FY+ +F Sbjct: 118 IFFQEVAIGQYLGAGGMTLVGQLCPLLQGVGYATMTIVFFLDVYYCIIIAWTLFYLISTF 177 Query: 139 SSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTA 198 +I +PW+ C W+T+ C+ D E T L + + + + N+T T Sbjct: 178 VNI-PNVPWKGCGNWWNTEDCF-----DGLEKIEETTDLVNSNSTNSTCNENVTLHHAT- 230 Query: 199 LRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFT 258 P EEY+ ++LG++ GIE G I+ + CL+ W++V+ + +G+ SGK+++F+ Sbjct: 231 ----PVEEYWERRLLGITPGIESIGGIQWELLGCLVIGWLLVYFIIRRGLHQSGKIIWFS 286 Query: 259 ALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGL 318 ALFPYVVL IL R VTL G+ G+L+Y+TP + +L + W D A QIFFA S G L Sbjct: 287 ALFPYVVLFILLGRAVTLEGSYNGLLYYVTPRWEELMSPGPWIDGATQIFFAYSIGTGAL 346 Query: 319 ITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGL 378 L SYNKF +NCY D+LI V N T AG V FS++G +A E V +VV G GL Sbjct: 347 PALGSYNKFHHNCYKDALITCVVNTLTCLLAGCVTFSILGHIALEQGTEVAKVVKSGPGL 406 Query: 379 AFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPN-FRQKKGWV 437 F+ YPEVV +LP + +W+I+FFVMLL LG+DS+F ++E+ T ++D +P+ R + Sbjct: 407 VFLTYPEVVLKLPGASMWAIIFFVMLLILGIDSEFCIVESFITGVVDNWPDLLRPHRNKF 466 Query: 438 VFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAAN-WSVLIIAIGECILIAWIYGAEKFCGD 496 + +L GL TN G+Y QLMD Y+A+ S+L + + I I+WI+GA KFC Sbjct: 467 TIAICCLMFLLGLPMVTNGGVYIFQLMDFYSASGMSILWVCFFQTIAISWIFGARKFCDC 526 Query: 497 IQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYG-HYVYPMWADAVG 553 I +M+G + W W + P + FI VF ++YKP YG +Y YP WA+ +G Sbjct: 527 IHQMMGIRLN---NFWYVCWVVFAPVIMAFIFVFQCVQYKPLRYGNNYEYPTWAEVIG 581 >UniRef50_Q01959 Cluster: Sodium-dependent dopamine transporter; n=131; Coelomata|Rep: Sodium-dependent dopamine transporter - Homo sapiens (Human) Length = 620 Score = 442 bits (1090), Expect = e-122 Identities = 217/554 (39%), Positives = 319/554 (57%), Gaps = 30/554 (5%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 +R W + DF NVWRFPYLCY NGGGAFL+P+ + +VIAG+PL +MEL Sbjct: 59 DRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMEL 118 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 + GQ+ G V+ K CP+ +G+G+ ++++S V +YN+IIAW + Y+ FSS + Sbjct: 119 ALGQFNREGAAGVW-KICPILKGVGFTVILISLYVGFFYNVIIAWALHYL---FSSFTTE 174 Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPA 204 LPW +C W++ +C D +G N ++ + PA Sbjct: 175 LPWIHCNNSWNSPNCSDAHPGDSSGDSSG-------LNDTFGTT--------------PA 213 Query: 205 EEYFTNQVLGL--SSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFP 262 EYF VL L S GI++ G R + CL+ V+++ L KGV++SGKVV+ TA P Sbjct: 214 AEYFERGVLHLHQSHGIDDLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMP 273 Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322 YVVL L RGVTLPGAI GI YL+ DF +L A VW DAA Q+ F+L +G LI S Sbjct: 274 YVVLTALLLRGVTLPGAIDGIRAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFS 333 Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIV 382 SYNKF+NNCY D+++ N TSF +G V+FS +G++A + +V + V G GL FI+ Sbjct: 334 SYNKFTNNCYRDAIVTTSINSLTSFSSGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFII 393 Query: 383 YPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVA 442 YPE + LP+S W+++FF+MLLTLG+DS ME+V T ++D F + + + Sbjct: 394 YPEAIATLPLSSAWAVVFFIMLLTLGIDSAMGGMESVITGLIDEFQLLHRHRELFTLFIV 453 Query: 443 VFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIG 502 + +L L TN G+Y L+D +AA S+L + E I +AW YG +F DIQ+M G Sbjct: 454 LATFLLSLFCVTNGGIYVFTLLDHFAAGTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTG 513 Query: 503 RQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGWTXXXXXXX 562 ++ L+ W W++++P L+F++V + + ++P YG Y++P WA+A+GW Sbjct: 514 QRPSLY---WRLCWKLVSPCFLLFVVVVSIVTFRPPHYGAYIFPDWANALGWVIATSSMA 570 Query: 563 XXXXXXXDQICSGP 576 + CS P Sbjct: 571 MVPIYAAYKFCSLP 584 >UniRef50_Q3I1M7 Cluster: Serotonin transporter; n=5; Schistosoma|Rep: Serotonin transporter - Schistosoma mansoni (Blood fluke) Length = 735 Score = 442 bits (1089), Expect = e-122 Identities = 219/539 (40%), Positives = 314/539 (58%), Gaps = 19/539 (3%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 +R W + DF N+WRFP++CY NGGGAFLIP+ VM + GLPL ++EL Sbjct: 142 KREIWDSKIDFLLAVIGFAVDLGNIWRFPFICYRNGGGAFLIPYLVMYIFGGLPLFYLEL 201 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 + GQY G + V+ + CPLF G+G+G+ I++S YYN IIAW +FYM + Sbjct: 202 ALGQYQRSGCLTVWKRICPLFSGVGFGICIIASYTAWYYNTIIAWALFYMIDAMKP---H 258 Query: 145 LPWQNCKAEWSTKHCYS-YEEADECEAQNGT--YYLRQCFNQSYSVSHNITALAKTALRR 201 +PW C W+T C + YE N + Y L + N S + S I K Sbjct: 259 IPWDGCNNWWNTNSCVTVYERLINHSILNASHKYELNELVNLSIA-SLKINGSGKVF--- 314 Query: 202 PPAEEYFTNQVLGL--SSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTA 259 EEYF +VL + + G G IR +++CL+A + IV+ L KGV+SSGK V+ TA Sbjct: 315 SSTEEYFYRRVLQIQYAEGYNNVGPIRWEISLCLMAVFTIVYFSLWKGVKSSGKAVWVTA 374 Query: 260 LFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLI 319 PYV+L IL RG+TL G++TGI +YLTP+FS L + VW DAA QIFF+L P +G L+ Sbjct: 375 TLPYVILSILLIRGLTLEGSLTGIKYYLTPNFSSLLSISVWSDAASQIFFSLGPGFGVLL 434 Query: 320 TLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLA 379 LSSYNKF NNCY D++I + N ATSF +G V+FSV+G++ + +++ V ++G GL Sbjct: 435 ALSSYNKFHNNCYRDAMITSFINCATSFVSGFVVFSVLGYMCFRMGKTMEDVANEGPGLV 494 Query: 380 FIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVF 439 FI YPE + L S W+I+F +ML+TLGLDS F +E + TAI+D P ++ V Sbjct: 495 FIAYPEAIATLAGSTFWAIIFMLMLITLGLDSTFGGLEAIITAIMDSVPALSGRREVFVL 554 Query: 440 IVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQR 499 V ++ ++G L TT G L ++D++ A S+L I EC+ + W YG ++FC D+Q Sbjct: 555 AVVIYCFIGALPSTTCGGYLVLTMLDRHGAPISILFIVFCECVALCWFYGTKRFCNDVQM 614 Query: 500 MIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEY--KPASYGHYVY--PMWADAVGW 554 M+G + ++ W W I+P L+ I + N + Y +P S VY W + W Sbjct: 615 MLGFKPGIF---WQICWAYISPIFLLGIFIANIVSYETQPVSVLGVVYEPTTWVIVLSW 670 >UniRef50_Q2ABP4 Cluster: Taurine transporter; n=2; Pteriomorphia|Rep: Taurine transporter - Crassostrea gigas (Pacific oyster) (Crassostrea angulata) Length = 671 Score = 439 bits (1081), Expect = e-121 Identities = 220/538 (40%), Positives = 323/538 (60%), Gaps = 22/538 (4%) Query: 29 WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQ 88 W + DF NVWRFP+LCY NGGGAFLIP+ +++ G+P+ F+E+S GQ Sbjct: 47 WANKLDFLLACIGFSVGLGNVWRFPFLCYRNGGGAFLIPYFTAVLLGGIPVFFLEVSLGQ 106 Query: 89 YAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQ 148 + + G + + K PLF+G+GY I+ ++ YN+I+ WT +Y+ SF+++ LPW Sbjct: 107 FMSEGGIGTW-KITPLFQGIGYACTIIVFLLNCEYNIILTWTFYYLFSSFNTV---LPWS 162 Query: 149 NCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRR-----PP 203 EW+++ C + + A + Y + + ++ +T +A T P Sbjct: 163 QGDNEWNSELC---RNSSKMAASLMSNYSKMASSVVSKLNDTMTTVAYTVATENTTKCDP 219 Query: 204 AEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPY 263 E++ ++VL LSSG++ G ++ +A+CLL AW++V+ C+ KG++SSGKV+YFTA PY Sbjct: 220 VTEFWESKVLQLSSGVDHAGTVKWDLALCLLLAWIVVYGCIWKGIKSSGKVMYFTATSPY 279 Query: 264 VVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSS 323 ++++IL RGVTL GA G+ FYL PD+S+L AQVW DA QIFF+ S + G L L S Sbjct: 280 ILMLILLIRGVTLDGAAEGLKFYLLPDWSKLQEAQVWVDAGTQIFFSYSISLGTLTALGS 339 Query: 324 YNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVY 383 YNKF +N Y D++I A N TS AGLVIFSV+GF+A + VSV V + G GLAFI Y Sbjct: 340 YNKFRHNSYRDAMIFAGVNSFTSILAGLVIFSVLGFMAKQQGVSVADVAESGPGLAFIAY 399 Query: 384 PEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNF-RQKKGWVVF--I 440 P V ++P++PLWS+LFFVM++ LGLDSQF +E TA +D +P++ R K +F I Sbjct: 400 PTAVAQMPVAPLWSVLFFVMIILLGLDSQFVGVEGFITACVDMYPHYLRIGKRREIFTGI 459 Query: 441 VAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRM 500 V +L GL T GMY QL D Y+A+ VL++A ECI++A+IYG ++ +++ M Sbjct: 460 VCFICFLIGLSMVTEGGMYVFQLFDYYSASRIVLVVAFFECIVVAYIYGINRYYDNLEMM 519 Query: 501 IGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYG----HYVYPMWADAVGW 554 G + + W +TP + I + I Y +Y Y YP WA VGW Sbjct: 520 FGFRI---APVMKICWMFVTPLFSLTIFIMGAISYSELTYKRKTYEYTYPSWAIGVGW 574 >UniRef50_Q7Q4L1 Cluster: Transporter; n=1; Anopheles gambiae str. PEST|Rep: Transporter - Anopheles gambiae str. PEST Length = 576 Score = 436 bits (1075), Expect = e-121 Identities = 215/574 (37%), Positives = 324/574 (56%), Gaps = 18/574 (3%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 +RG+W + +F NVWRFPYLCY NGGGAFL+P+ +MLV+ G+PL F+E Sbjct: 13 KRGHWASKTEFILSCIGYAIGLGNVWRFPYLCYRNGGGAFLVPYLLMLVLCGIPLFFLET 72 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 GQ++ G + V+ K PL +G G +V+++ I YY II++ + ++ + S+ Q Sbjct: 73 CLGQFSGTGCITVF-KIVPLLKGAGIAIVVLNLICNAYYIAIISYPLLFL---WRSLQAQ 128 Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPA 204 LPW++C W+T C E + Y + + L L Sbjct: 129 LPWESCGNAWNTPRCLELRGDQHVELFLNNSAM--AIGDRYLLEVVESLLEHQGLFLVVV 186 Query: 205 EEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264 +N++L +S GIE+ G I + +C + AW+++F C+ KGVQS GKVVY TA FP+ Sbjct: 187 ---CSNEILHISEGIEQMGGIVWPLLLCDVIAWIVIFGCIAKGVQSVGKVVYCTATFPFA 243 Query: 265 VLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSY 324 +L +L RG+TLPGA+ GI FY+ P +SQL N +VW DAA+QIF++L P WGG++ ++SY Sbjct: 244 ILAVLLVRGITLPGALEGIKFYIMPQWSQLLNLRVWADAAIQIFYSLGPGWGGILNMASY 303 Query: 325 NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYP 384 N+F NN +DS+++ + N TS AG V+FSV+G+ +H+ + V G GLAFI YP Sbjct: 304 NQFKNNTKLDSIVIPIVNCGTSILAGFVVFSVLGYFSHQTGLPVASAATGGPGLAFITYP 363 Query: 385 EVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVF 444 E ++ LP+SPLW+ LFF ML LG+DS F +E + ++++D P R K + + A Sbjct: 364 EAISMLPLSPLWACLFFSMLFFLGVDSMFVQIEAIVSSVMDVLPRLRPMK---LQVTAGT 420 Query: 445 GYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQ 504 +L L+ GMY +QL+D Y+ + SV+++ I E I + WIYG E+F D++ MI R+ Sbjct: 421 CFLLFLLSIACGGMYLVQLLDWYSGSISVILVCIVEVITVGWIYGCEQFVRDVEFMIDRK 480 Query: 505 SKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGWTXXXXXXXXX 564 + + W W+ ITP L FI + SY + YP WA VGW Sbjct: 481 VERF---WIVSWKYITPIVLTFIFTTTIVYNTEVSYNGFSYPRWAIGVGWASCLVSILCI 537 Query: 565 XXXXXDQICSGPDDLTIMEKARVLARPTEEWGQA 598 ++ LT K ++ A ++WG A Sbjct: 538 PVFASYKLLHTKGSLTKRFKTQLKA---QDWGPA 568 >UniRef50_P31645 Cluster: Sodium-dependent serotonin transporter; n=58; Coelomata|Rep: Sodium-dependent serotonin transporter - Homo sapiens (Human) Length = 630 Score = 434 bits (1069), Expect = e-120 Identities = 215/541 (39%), Positives = 326/541 (60%), Gaps = 36/541 (6%) Query: 18 LSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGL 77 ++E + ER W + DF NVWRFPY+CY NGGGAFL+P+T+M + G+ Sbjct: 71 VAELHQGERETWGKKVDFLLSVIGYAVDLGNVWRFPYICYQNGGGAFLLPYTIMAIFGGI 130 Query: 78 PLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVS 137 PL +MEL+ GQY G ++++ K CP+F+G+GY + I++ + YYN I+AW ++Y+ S Sbjct: 131 PLFYMELALGQYHRNGCISIWRKICPIFKGIGYAICIIAFYIASYYNTIMAWALYYLISS 190 Query: 138 FSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKT 197 F+ QLPW +CK W+T +C +Y D N T+ L +S S Sbjct: 191 FTD---QLPWTSCKNSWNTGNCTNYFSED-----NITWTL-------HSTS--------- 226 Query: 198 ALRRPPAEEYFTNQVLGL--SSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVV 255 PAEE++T VL + S G+++ G I +A+C++ + +++ + KGV++SGKVV Sbjct: 227 -----PAEEFYTRHVLQIHRSKGLQDLGGISWQLALCIMLIFTVIYFSIWKGVKTSGKVV 281 Query: 256 YFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAW 315 + TA FPY++L +L RG TLPGA G+LFYL P++ +L VW DAA QIFF+L P + Sbjct: 282 WVTATFPYIILSVLLVRGATLPGAWRGVLFYLKPNWQKLLETGVWIDAAAQIFFSLGPGF 341 Query: 316 GGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVV-DQ 374 G L+ +SYNKF+NNCY D+L+ +V N TSF +G VIF+V+G++A N V V D Sbjct: 342 GVLLAFASYNKFNNNCYQDALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNEDVSEVAKDA 401 Query: 375 GAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPN-FRQK 433 G L FI Y E + +P S ++I+FF+ML+TLGLDS FA +E V TA+LD FP+ + ++ Sbjct: 402 GPSLLFITYAEAIANMPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHVWAKR 461 Query: 434 KGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKF 493 + V V + + G L+ T G Y ++L+++YA +VL +A+ E + ++W YG +F Sbjct: 462 RERFVLAVVITCFFGSLVTLTFGGAYVVKLLEEYATGPAVLTVALIEAVAVSWFYGITQF 521 Query: 494 CGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVG 553 C D++ M+G S W W W I+P L+FI+ + Y YP W+ +G Sbjct: 522 CRDVKEMLG-FSPGW--FWRICWVAISPLFLLFIICSFLMSPPQLRLFQYNYPYWSIILG 578 Query: 554 W 554 + Sbjct: 579 Y 579 >UniRef50_UPI0000E4A7A9 Cluster: PREDICTED: similar to choline transporter; n=8; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to choline transporter - Strongylocentrotus purpuratus Length = 855 Score = 426 bits (1049), Expect = e-117 Identities = 218/543 (40%), Positives = 319/543 (58%), Gaps = 20/543 (3%) Query: 23 EPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFM 82 + RG WT + DF NVWRFPYLCY NGGGAFLIP+ + L++ G+P + + Sbjct: 220 QKSRGTWTSQLDFLLALIGASVGLGNVWRFPYLCYKNGGGAFLIPYFICLILGGIPQLIL 279 Query: 83 ELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIF 142 E+ GQ+ V ++ CP+F+GLG + + + YY +I+AW ++YM +SF+S Sbjct: 280 EIGLGQWTNQAAVTAWD-ICPIFKGLGGAGMFIQFFLDTYYIVIMAWALYYMFMSFTS-- 336 Query: 143 YQLPWQNCKAEWSTKHCYSY--EEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALR 200 +LP+ +C EW+T C + D E ++ + + S N+T Sbjct: 337 -KLPYSHCDNEWNTPCCLATGASSLDANETTTAMTSTEMSYDPTGTPSWNLTDPCNGTTI 395 Query: 201 RPPAEEYFTNQVLG--LSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFT 258 E ++ ++L LS GIE+ G I + +C+ AW + +LC+CKGV++SGKVVYFT Sbjct: 396 SSTVE-FWDRKILQIHLSDGIEQLGGINWQLLLCMFFAWFLCYLCICKGVKTSGKVVYFT 454 Query: 259 ALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGL 318 A FPY+++ IL R VTL GA+ GI++YL PD S+L ++QVW DAA QIFF+ S G L Sbjct: 455 APFPYILMTILLIRAVTLEGAMDGIVYYLKPDISRLNDSQVWMDAATQIFFSYSLGQGVL 514 Query: 319 ITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGL 378 I L SYNK +N D+LI +V+N TS ++G VIF+V+GF+A + V V V G GL Sbjct: 515 IALGSYNKHKHNFIRDALIFSVANTGTSLYSGFVIFAVLGFMAGQQGVDVSVVAKSGPGL 574 Query: 379 AFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK---KG 435 AFI YPE +T++P S LW++LFF+ LL LG+DSQF +E I+D FPN K + Sbjct: 575 AFIAYPEAITQMPASTLWAVLFFLCLLVLGIDSQFVGVEGFVATIVDLFPNTLLKGHRRE 634 Query: 436 WVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLI-IAIGECILIAWIYGAEKFC 494 V +F + G+ T GMY QL D YAA+ VL+ +++ E I I W YG +F Sbjct: 635 IFCIFVCLFFCIAGIPMCTYGGMYIFQLFDYYAASGFVLLWVSMFESITIGWAYGGFRFM 694 Query: 495 GDIQRMIGRQSKLWV--YLWSAMWRIITPAALVFILVFNWIEYKPASYGH-YVYPMWADA 551 ++ M G + W+ Y+ +A W ++P I +F+ ++YKP +Y + YVYP W Sbjct: 695 KNVTEMSGVK---WISPYMITA-WIFLSPLFTFAIFIFSLVKYKPLTYNNTYVYPWWGYM 750 Query: 552 VGW 554 +GW Sbjct: 751 IGW 753 >UniRef50_Q5J2D5 Cluster: GABA transporter protein; n=2; Caenorhabditis|Rep: GABA transporter protein - Caenorhabditis elegans Length = 610 Score = 426 bits (1049), Expect = e-117 Identities = 229/589 (38%), Positives = 324/589 (55%), Gaps = 27/589 (4%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 ER W+ DF NVWRFPYLCY NGGGAFLIP+ + LV G PL +E Sbjct: 9 EREQWSSWADFIMSCIGYAIGLGNVWRFPYLCYQNGGGAFLIPYCISLVFCGAPLFILET 68 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 S+GQ ++G + ++ K CP+F+G+G +++ + +YY ++++W Y+ SF+ Sbjct: 69 SWGQLMSVGGLGMF-KICPIFKGVGIAAAVMAFWLNIYYIVVLSWAATYLYNSFT--MSD 125 Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNG----------TYYLRQCFNQSYSVSH--NIT 192 +PW+NC W+T +C S C++ T+ + + + V N T Sbjct: 126 VPWKNCDHAWNTPNCRSEYVKIPCDSNRTIAEFFNVKVLTHDHIHEYKKQFFVGEKMNWT 185 Query: 193 ALAKTALRR-PPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSS 251 + L P +E++ ++VLG+SSG+E G IR +A+ LL W+I +LC+ KGV+ + Sbjct: 186 VCSAADLSVVSPVKEFWNHRVLGISSGLENPGGIRWDLALFLLLVWIICYLCIFKGVKWT 245 Query: 252 GKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFAL 311 GKVVY TA FPY++L L RG+TL GA G+ FYL PDFS+L ++VW DA Q+FF+ Sbjct: 246 GKVVYITASFPYMMLFCLLIRGLTLEGAGVGLEFYLKPDFSKLLESKVWVDAVTQVFFSY 305 Query: 312 SPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRV 371 G L+ L SYNKF+NN Y +L V N TS FAG VIFS IGF+A + SV V Sbjct: 306 GLGLGALVALGSYNKFNNNVYKQALTVCFVNSGTSVFAGFVIFSFIGFMATQQEKSVAEV 365 Query: 372 VDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFR 431 G GL F+ YP + +LP + WS LFF+M+L LG+DSQF ME TAI+D FP R Sbjct: 366 AQAGPGLLFLAYPSGILQLPYTQFWSCLFFLMVLFLGVDSQFCTMEGFFTAIIDEFPQIR 425 Query: 432 QKK-GWVVF--IVAVFGYLGGLIFTTNSGMYWLQLMDKYAAN-WSVLIIAIGECILIAWI 487 +KK G +F ++ V YL GL T G Y QL D YAA+ W++L + ECI I+W Sbjct: 426 RKKYGREIFVGVICVISYLIGLTTVTEGGFYVFQLFDFYAASGWALLWLLFFECIAISWS 485 Query: 488 YGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYG--HYVY 545 G +++ ++ MIG W W W TP+ +L+F I+Y+P +Y Y Sbjct: 486 LGIDRWYEHMKSMIGYYPSAW---WKFCWVFATPSVCFGVLLFGLIKYQPLRIDAYNYDY 542 Query: 546 PMWADAVGWTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEE 594 P+W GW P T+ EK ++L RP E Sbjct: 543 PVWGHIFGWFLSLSSMLCIPGYAIWIWFKTPG--TVQEKIKLLCRPDIE 589 >UniRef50_Q03614 Cluster: Sodium-dependent dopamine transporter; n=6; Bilateria|Rep: Sodium-dependent dopamine transporter - Caenorhabditis elegans Length = 615 Score = 425 bits (1047), Expect = e-117 Identities = 211/546 (38%), Positives = 316/546 (57%), Gaps = 35/546 (6%) Query: 19 SEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLP 78 +E +P R W+G+ DF N+WRFPYLC+ NGGG FLIP+++M+++ G+P Sbjct: 33 TEPKDPAREQWSGKLDFLLSVVGFAVDLGNIWRFPYLCFKNGGGVFLIPYSIMVLLTGVP 92 Query: 79 LMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSF 138 L +MEL GQY G + + + CPLF+G+GY +++ + V +YN+I+AW + Y+ SF Sbjct: 93 LFYMELCLGQYYRKGAITTWGRICPLFKGIGYCVILTAFYVDFFYNVILAWGLHYLYTSF 152 Query: 139 SSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTA 198 S + LPW +C +++ CY +++ GT R NQS S + I+A Sbjct: 153 S---FNLPWASCNNSYNSPACYEPHWSED-----GTAMCRSA-NQSVS-AEKISA----- 197 Query: 199 LRRPPAEEYFTNQVLGLSSG----------IEETGEIRLGMAMCLLAAWVIVFLCLCKGV 248 AEEYF LGL + + G +R +A+ L ++I + + KG+ Sbjct: 198 -----AEEYFYKGFLGLHEANAPNSHVIRSVTDLGNVRWDIALSLFVVYLICYFSMWKGI 252 Query: 249 QSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIF 308 +SGKVV+FTALFPYVVL ILF RGVTLPG GI +YL P+F L VW DAA Q+F Sbjct: 253 HTSGKVVWFTALFPYVVLGILFIRGVTLPGWQNGIEYYLRPNFEMLKRPSVWQDAATQVF 312 Query: 309 FALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSV 368 F+L P +G L+ SSYN F NN Y+D+L + N ATSF +G VIFSV+G+++ + + Sbjct: 313 FSLGPGFGVLMAYSSYNDFHNNVYVDALFTSFINCATSFLSGFVIFSVLGYMSCKSGKPI 372 Query: 369 DRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFP 428 + V +G GL F+VYPE ++ +P +P WS+LFF+ML+TLGLDS F E + T + D FP Sbjct: 373 EAVAQEGPGLVFVVYPEALSTMPYAPFWSVLFFLMLMTLGLDSSFGGSEAIITGLSDEFP 432 Query: 429 NFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIY 488 ++ + V + F + G+ T G+ ++ + Y W +LI E ++IA+IY Sbjct: 433 ILKKNREVFVGCLFAFYMVIGIAMCTEGGILIMEWLIIYGTTWGLLIAVFCEAMVIAYIY 492 Query: 489 GAEKFCGDIQRMIG-RQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPM 547 G +F D++ M+G R W + WS P L+ ++ N+I Y+ +Y Y YP Sbjct: 493 GLRQFVHDVKEMMGFRPGNYWKFCWSC----AAPFILLSMITSNFINYQALTYQDYTYPT 548 Query: 548 WADAVG 553 A+ +G Sbjct: 549 AANVIG 554 >UniRef50_P51905 Cluster: Sodium-dependent serotonin transporter; n=7; Protostomia|Rep: Sodium-dependent serotonin transporter - Drosophila melanogaster (Fruit fly) Length = 622 Score = 424 bits (1045), Expect = e-117 Identities = 210/535 (39%), Positives = 317/535 (59%), Gaps = 38/535 (7%) Query: 23 EPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFM 82 E R W + +F NVWRFPY+CY NGGGAFL+P+ + L+ GLPL +M Sbjct: 71 ERTRETWGQKAEFLLAVIGFAVDLGNVWRFPYICYQNGGGAFLVPYCLFLIFGGLPLFYM 130 Query: 83 ELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIF 142 EL+ GQ+ G ++++ + CP +G+GY + ++ + +YYN II W ++Y+ SF+S Sbjct: 131 ELALGQFHRCGCLSIWKRICPALKGVGYAICLIDIYMGMYYNTIIGWAVYYLFASFTS-- 188 Query: 143 YQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRP 202 +LPW +C W+T++C S N T LA + Sbjct: 189 -KLPWTSCDNPWNTENCMQV------------------------TSENFTELATS----- 218 Query: 203 PAEEYFTNQVLGL--SSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTAL 260 PA+E+F +VL +G++ G ++ +A+C+ +V+V+ L KGV+S+GKVV+ TAL Sbjct: 219 PAKEFFERKVLESYKGNGLDFMGPVKPTLALCVFGVFVLVYFSLWKGVRSAGKVVWVTAL 278 Query: 261 FPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLIT 320 PYVVL+IL RGV+LPGA GI +YLTP++ +L N++VW DAA QIFF+L P +G L+ Sbjct: 279 APYVVLIILLVRGVSLPGADEGIKYYLTPEWHKLKNSKVWIDAASQIFFSLGPGFGTLLA 338 Query: 321 LSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAF 380 LSSYNKF+NNCY D+LI + N TSF AG VIFSV+G++A+ S+D+V +G GL F Sbjct: 339 LSSYNKFNNNCYRDALITSSINCLTSFLAGFVIFSVLGYMAYVQKTSIDKVGLEGPGLVF 398 Query: 381 IVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPN-FRQKKGWVVF 439 IVYPE + + S WSI+FF+ML+TLGLDS F +E + TA+ D +P +++ V Sbjct: 399 IVYPEAIATMSGSVFWSIIFFLMLITLGLDSTFGGLEAMITALCDEYPRVIGRRRELFVL 458 Query: 440 IVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQR 499 ++ F +L L T G+ + ++ Y ++L + E + W YG ++F D+++ Sbjct: 459 LLLAFIFLCALPTMTYGGVVLVNFLNVYGPGLAILFVVFVEAAGVFWFYGVDRFSSDVEQ 518 Query: 500 MIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGW 554 M+G + L+ W W I+P L+ I +F+ + YK Y YP W+ VGW Sbjct: 519 MLGSKPGLF---WRICWTYISPVFLLTIFIFSIMGYKEMLGEEYYYPDWSYQVGW 570 >UniRef50_UPI0000E47635 Cluster: PREDICTED: similar to high-affinity serotonin transporter; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to high-affinity serotonin transporter - Strongylocentrotus purpuratus Length = 641 Score = 418 bits (1029), Expect = e-115 Identities = 206/534 (38%), Positives = 316/534 (59%), Gaps = 39/534 (7%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 ER W + DF N+WRFPY+CY NGGGAFL+P+ +M + G+P ++ME+ Sbjct: 90 ERAVWGKKADFLLSVIGFTVDLGNIWRFPYICYKNGGGAFLVPYALMAIFGGVPFLYMEM 149 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 + GQY G + V+ + CP+ G+GY + I++ V +Y+ I AW+++Y+ SF++ Sbjct: 150 ALGQYQRTGCITVWRRICPIMGGIGYAICIINCYVGFFYSTITAWSVYYLIASFATT--- 206 Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPA 204 LPW +C +W+ T + F +++S + ++T PA Sbjct: 207 LPWTSCDNDWN------------------TEFCASPFAENFS-NTSVT----------PA 237 Query: 205 EEYFTNQVLG--LSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFP 262 E+F +V+G LS+GI + G ++ +A+CLL +VIV+ + KG+++SGKVV+ TA P Sbjct: 238 TEFFERKVIGSHLSTGIGDLGGLKWELALCLLLLFVIVYFSIWKGIKASGKVVWVTATLP 297 Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322 Y L++L RGVTL GA +GI++YL P + L NA VW DAAVQ+FF+L P +G ++ S Sbjct: 298 YFCLIVLLIRGVTLEGASSGIIYYLKPKWHLLRNAGVWVDAAVQVFFSLGPGFGVILAFS 357 Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIV 382 SYNK NNC+ D+LI + N TSF AG IFSV+GF++ + ++ V G GL +I Sbjct: 358 SYNKLHNNCFKDALITSGINCFTSFLAGFAIFSVLGFMSVQQGRDIEEVTPDGPGLIYIA 417 Query: 383 YPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWV-VFIV 441 PE +++LP S W+++FFVM+++LGLDS F +E++ TA DR P K + V V Sbjct: 418 IPEAISQLPGSTWWAVIFFVMIISLGLDSTFGGLESIITAWCDRNPKTIGKHREIFVACV 477 Query: 442 AVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMI 501 F +LG L T G Y QL++ Y A+ ++L++ + E I I W YG + F DI+ MI Sbjct: 478 VCFIFLGSLTTVTYGGQYVFQLLESYGASTTLLLVVVLEAISITWFYGLQNFTSDIRTMI 537 Query: 502 GRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKP-ASYGHYVYPMWADAVGW 554 GR ++ W W I++PA L+F++VF ++P + YP W+ VGW Sbjct: 538 GRTPSVY---WQLCWSILSPAMLLFVVVFGLFMHRPMVGFQGEPYPQWSIGVGW 588 >UniRef50_UPI00015B4B04 Cluster: PREDICTED: similar to neurotransmitter transporter; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to neurotransmitter transporter - Nasonia vitripennis Length = 992 Score = 417 bits (1028), Expect = e-115 Identities = 206/557 (36%), Positives = 324/557 (58%), Gaps = 39/557 (7%) Query: 6 CLKGDEEKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFL 65 C D+ ++ P E +P R +W + F NVWRFPYLCY +GGG FL Sbjct: 382 CTSFDDGDAEDP-GEYRQPRRPHWENKVQFVLACIGYSVGLGNVWRFPYLCYKSGGGVFL 440 Query: 66 IPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNL 125 IP+ ++L++ G+PL++MELS GQ+ GP+ + CPLF+G G V++S ++ Y+N+ Sbjct: 441 IPYFLILIVCGVPLLYMELSIGQFTRRGPIGALGQICPLFKGAGLSSVVISFLMSTYHNV 500 Query: 126 IIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSY 185 IIA+ I+Y I PW C+ +W++ C+S AD N T Sbjct: 501 IIAYAIYYFFTGCKPI---QPWSRCRNKWNSPDCWS---ADVMTNNNNT----------- 543 Query: 186 SVSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLC 245 + + P+ E+F N+VL +SSGIEE G +R +A CL++AWVIV+ + Sbjct: 544 ----------RPKHPKIPSAEFFDNKVLQISSGIEEPGMLRWELAACLISAWVIVYFSIW 593 Query: 246 KGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAV 305 K ++SS +V Y TA P++++ I R +TL GA G+ F+ PD+ L +A+VW +AA Sbjct: 594 KSIKSSARVRYLTATLPFLLIFIFLTRSLTLEGADKGLQFFFRPDWQLLKDAKVWVNAAA 653 Query: 306 QIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELN 365 QIF ++ A+G +I +SYNKF NN ID++ V++ N + G+ F+ IG +A E N Sbjct: 654 QIFNSVGIAFGSMICFASYNKFHNNILIDTVAVSLINACSCLLVGIFAFATIGNIAVEQN 713 Query: 366 VSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILD 425 ++V V+ G GL F+VYP+ + ++P +W++LFF ML+ L L+SQFA++E V T+I D Sbjct: 714 MTVPEVLSDGPGLVFVVYPQALAKMPWPQMWAMLFFFMLVCLSLNSQFAIVEVVVTSIQD 773 Query: 426 RFPNFRQK----KGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGEC 481 FP + +K +V +V + +L GL T G+Y+ QL+D YAA+ S++ +A E Sbjct: 774 GFPKWVKKHLLCHEMLVLLVCIVSFLFGLPNITQGGIYFFQLIDHYAASISIMFLAFFEV 833 Query: 482 ILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASY- 540 I I+W YG + C +++ M GR ++ + W + +P ++ + VF+ I+Y+P Y Sbjct: 834 IAISWFYGVRRLCSNVKEMTGRVPSIY---FRFCWLVASPLLIMAVWVFSLIDYEPPHYT 890 Query: 541 ---GHYVYPMWADAVGW 554 G Y YP WA+A+GW Sbjct: 891 RSDGKYTYPWWAEAIGW 907 >UniRef50_Q9VLY6 Cluster: Transporter; n=7; Endopterygota|Rep: Transporter - Drosophila melanogaster (Fruit fly) Length = 590 Score = 416 bits (1025), Expect = e-115 Identities = 200/535 (37%), Positives = 321/535 (60%), Gaps = 35/535 (6%) Query: 21 EIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLM 80 E + RG W + +F NVWRFPYLCY +GG AFLIP+ +M+++AG+PL Sbjct: 19 ERDENRGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFLIPYLLMVILAGIPLF 78 Query: 81 FMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSS 140 +ME+ GQ+++ G ++ + PL +G G V+V++ + YY++II++ I + F Sbjct: 79 YMEILIGQFSSTGCTGMF-RMTPLLKGTGIAQVVVNAYCVCYYSVIISYPI---RMIFYC 134 Query: 141 IFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALR 200 F ++PW++C W+T C + A + QN + + KT+ Sbjct: 135 FFKKVPWEDCSNSWNTDDCVT---ASDMGKQNSS------------------DVFKTS-- 171 Query: 201 RPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTAL 260 A+E+F +VL +S+ I + G + L+ W+I++ CL +G++S GKVVYFT Sbjct: 172 ---ADEFFHLEVLRISTDISDLGGMVWEQLTALIITWIIIYFCLMRGIKSVGKVVYFTVP 228 Query: 261 FPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLIT 320 FPY++L IL RG TLPGA GI FYL P++ +L + +VW DAAVQ+FF + P WGG++ Sbjct: 229 FPYLLLFILLIRGATLPGAWKGIKFYLYPEWHRLLDLKVWADAAVQMFFGIGPGWGGIVN 288 Query: 321 LSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAF 380 ++S++ F NN DS+++ N+ TS AG V+FSV+GFL+ + + V+ V GAGLAF Sbjct: 289 MASFSSFRNNAKCDSVLIVSINVFTSLLAGFVVFSVLGFLSEKSGIPVESVATGGAGLAF 348 Query: 381 IVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFI 440 + YPE + LP+ LW+++FF ML LG+DS F +E + ++ILD + R K + I Sbjct: 349 VTYPEAIALLPVPQLWALMFFFMLFLLGIDSVFVQLEAIMSSILDEWYWVRSHKCKLTLI 408 Query: 441 VAVFGYLG-GLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQR 499 + +LG I TN GM+ LQL D Y++ +V++I + E I++AWIYG + F D++ Sbjct: 409 SCLI-FLGLSSIMCTNGGMFILQLFDWYSSAIAVIVICLVEIIMVAWIYGIKNFMLDVEF 467 Query: 500 MIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGW 554 M+G++ L+ W +W+++TP ++FIL+ + + + +Y + YP WA +GW Sbjct: 468 MLGKRPTLY---WRIVWQVVTPVIIIFILITSIVFIRTITYNNIPYPQWAIIIGW 519 >UniRef50_Q4F9L7 Cluster: High-affinity octopamine transporter protein; n=12; Arthropoda|Rep: High-affinity octopamine transporter protein - Ostrinia nubilalis (European corn borer) Length = 745 Score = 409 bits (1008), Expect = e-113 Identities = 217/559 (38%), Positives = 315/559 (56%), Gaps = 34/559 (6%) Query: 4 QACLKGDEEKSKAPLS-EEIEPERGN--WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNG 60 + C+ D K S + +P+ G W DF NVWRFPYLCY NG Sbjct: 154 EECIYSDSSKRVRTSSLKPGDPDDGRETWGTGADFLLSIIGFAVDLANVWRFPYLCYRNG 213 Query: 61 GGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVM 120 GGAFLIP+T+ML+ +PL +MEL GQY GP+ ++ K CPLF+G+G+ V+V+ V Sbjct: 214 GGAFLIPYTLMLIFGAVPLFYMELILGQYNRQGPITIW-KICPLFKGVGFCAVMVAFYVS 272 Query: 121 LYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQC 180 YYN+II W +++ S S +LPW +C W+T C+ +A N T Q Sbjct: 273 FYYNVIIGWAFYFLVSSARS---ELPWVHCDNAWNTDQCW---DAARLNNTNRTEIPYQG 326 Query: 181 FNQSYSVSHNITALAKTALRRPPAEEYFTNQVLGL--SSGIEETGEIRLGMAMCLLAAWV 238 +SH PA E+F VL + S G+ + G + + +CL +V Sbjct: 327 -----PLSHFT-----------PASEFFHRAVLEMQHSEGLNDLGFPKWQLTVCLGLVYV 370 Query: 239 IVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQ 298 ++L L KGV+SSGKVV+ TA PYVVL IL RG+ LPGA GI +YL P+ ++L + Q Sbjct: 371 TLYLSLFKGVKSSGKVVWMTATMPYVVLSILLARGLLLPGATRGIAYYLQPELTRLKDTQ 430 Query: 299 VWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIG 358 VW DAAVQIF+++ +G ++ +SYN F NNCY D L+ + N TSFF+G VIF+ +G Sbjct: 431 VWVDAAVQIFYSVGAGFGVHLSYASYNTFHNNCYRDCLVTTLVNCFTSFFSGFVIFTYLG 490 Query: 359 FLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMET 418 F++++ V + V +G GL F VYPE V LP + LW++LFF ML+ LGLDS +E Sbjct: 491 FMSYKQGVPISSVATEGPGLVFQVYPEAVATLPGASLWAMLFFFMLIMLGLDSGMGGLEC 550 Query: 419 VTTAILD--RFPNFRQ-KKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLI 475 V T +LD R + ++ F+V + I T G+Y L+D YAA S+L Sbjct: 551 VITGLLDAARASGAKHLRREHFTFVVVCVSFCVACINVTPGGIYMFHLLDTYAAGISLLC 610 Query: 476 IAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEY 535 A+ E + ++W YG +KF D++ M+G + L+ W W+ ++P ++ ++VF + Sbjct: 611 SALFEAVAVSWFYGLKKFSDDVEEMLGFRPGLY---WRICWKFVSPTFIIGVVVFGLLYQ 667 Query: 536 KPASYGHYVYPMWADAVGW 554 +P Y Y YP WA +GW Sbjct: 668 QPLVYQTYTYPQWAVVLGW 686 >UniRef50_UPI000051A91B Cluster: PREDICTED: similar to inebriated CG15444-PB, isoform B; n=2; Endopterygota|Rep: PREDICTED: similar to inebriated CG15444-PB, isoform B - Apis mellifera Length = 888 Score = 409 bits (1007), Expect = e-112 Identities = 197/538 (36%), Positives = 319/538 (59%), Gaps = 36/538 (6%) Query: 23 EPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFM 82 + R +W + F N+WRFPYLCY +GGG FL+P+ ++L++ G+PL++M Sbjct: 297 QSRRPHWANKMQFVLACIGYSVGLGNIWRFPYLCYKSGGGVFLVPYFLILIVCGVPLLYM 356 Query: 83 ELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIF 142 ELS GQ+ GP+ + CPLF+G G V++S ++ Y+N+IIA+ I+Y +F + Sbjct: 357 ELSIGQFTRRGPIGALGQICPLFKGAGLSSVVISFLMSTYHNVIIAYAIYYFFTAFRA-- 414 Query: 143 YQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRP 202 + PW +C+ W+T C+ +YS N T + R Sbjct: 415 -KQPWSDCENSWNTLACWL---------------------PTYSGIDNRT---RPNASRT 449 Query: 203 PAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFP 262 PAEE+F N+VL +S+GIEE+G +R + CL+ AW++V+ + K ++SS +V Y TA P Sbjct: 450 PAEEFFDNKVLQISNGIEESGPLRWELIACLITAWIMVYFSVWKSIKSSAQVRYLTATLP 509 Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322 ++++V+ R +TL GA G+ F+ P + LA+A+VW A QIF ++ A+G +I + Sbjct: 510 FLLIVVFLMRSLTLEGADKGLQFFFHPRWELLADAKVWIYATAQIFNSVGIAFGSMICFA 569 Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIV 382 SYNKF N ID++ V++ N +S G+ F+ IG +A E N+SV+ V+ G GL F++ Sbjct: 570 SYNKFHNTILIDTMAVSLINGFSSLLVGIFSFATIGNIALEQNMSVEDVLTDGPGLVFVL 629 Query: 383 YPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK----KGWVV 438 YP+ + ++P S +W++LFF ML+ L L+SQFA++E V T+I D FP + ++ +V Sbjct: 630 YPQALAKMPASQVWAVLFFFMLVCLSLNSQFAIVEVVVTSIQDGFPKWVKRHLTCHEMLV 689 Query: 439 FIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQ 498 ++ V +L GL + G+Y+ QL+D YAA+ S++ +A E I I+W YG + C +++ Sbjct: 690 LLICVISFLFGLPNISQGGIYFFQLIDHYAASISIMFLAFFEVIAISWFYGVRRLCNNVK 749 Query: 499 RMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASY--GHYVYPMWADAVGW 554 M GR + + W I P ++ + VF+ I+Y+P +Y G Y YP WA+A+GW Sbjct: 750 EMTGRVPSSY---FRFCWLIAAPFLIMAVWVFSLIDYEPPTYHNGEYKYPWWAEAIGW 804 >UniRef50_Q9N3C7 Cluster: Transporter; n=3; Caenorhabditis|Rep: Transporter - Caenorhabditis elegans Length = 671 Score = 407 bits (1001), Expect = e-112 Identities = 215/614 (35%), Positives = 332/614 (54%), Gaps = 39/614 (6%) Query: 11 EEKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTV 70 +E A L R W + +F N+WRFP +CY +GGGAFLIP+ + Sbjct: 85 KEGRVAALRRRSSMVRDKWATKMEFLLAVVGYAVDLGNIWRFPSVCYKHGGGAFLIPYFI 144 Query: 71 MLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWT 130 ML+I GLP+ +MEL GQ+ G V+++ K CPLFRG+GYG+ + + + ++YN IIA Sbjct: 145 MLMIGGLPMFYMELVLGQFHRSGCVSIWRKVCPLFRGIGYGICCICTFIAIFYNAIIAQA 204 Query: 131 IFYMTVSFSSIF-YQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSH 189 +++ VS S I+ ++PW +C W+T C +D+ ++S Sbjct: 205 VYFAIVSLSKIWDSEVPWASCGNPWNTPRC-----SDDLNV---------------TISR 244 Query: 190 NITALAKTALRRPPAEEYFTNQVLGL--SSGIEETGEIRLGMAMCLLAAWVIVFLCLCKG 247 N T L P+EEY+ +VL + S+G ++ G ++ MA+CLLA +++V+ L KG Sbjct: 245 NGTPLTT------PSEEYYLYKVLEVQKSTGFDDLGGVKTSMAVCLLAVFIMVYFALWKG 298 Query: 248 VQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQI 307 QSSGK+V+ TA PY++L IL RG+ LPGA G+ +Y+TPDF +L + VW AA QI Sbjct: 299 PQSSGKIVWVTATAPYIILSILLIRGLLLPGAKNGLYYYVTPDFEKLKDPAVWSAAATQI 358 Query: 308 FFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVS 367 FF+L P +G L+ LSSYN F+NNCY D++ ++ N ATSFF+G V+FS +G+++ N Sbjct: 359 FFSLGPGFGVLLALSSYNDFNNNCYRDAVTTSIINCATSFFSGCVVFSTLGYMSLLTNKP 418 Query: 368 VDRVV-DQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDR 426 ++ VV + A L FIVYP+ + + S WS +FFVML+TLG+DS FA +E T D Sbjct: 419 INEVVGEHDASLIFIVYPQALATMDYSCFWSFIFFVMLITLGIDSTFAGIEAFITGFCDE 478 Query: 427 FPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAW 486 + + W V ++ + Y + G + + +D+Y + SVL I E I + W Sbjct: 479 SRFLSKNRKWFVLVICIIYYFLSFPAISYGGQFVIPFLDEYGVSLSVLFIVTCEMIAVCW 538 Query: 487 IYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPA--ALVFILVFNWIEYKPASYGHYV 544 YG ++F DI+ M+G ++ W W +P +++FI+ +KP Y Sbjct: 539 FYGVDQFSKDIRAMLGFYPGIY---WRVCW-TCSPVFISVIFIMTVYNSSFKPIQMASYT 594 Query: 545 YPMWADAVGWTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWGQAGSTATC 604 +P W+ +GW + SG T+ E+ R P + A S A Sbjct: 595 FPWWSVILGWFLRLLSVLAIPVFAIIYLLSGTG--TLYERFRWAITPQQRRNSATSLAAD 652 Query: 605 LSTLRVETELSPPV 618 T +++ L P+ Sbjct: 653 -PTQIIDSSLLDPI 665 >UniRef50_Q7YZB6 Cluster: Sodium and chloride dependent proline transporter; n=2; Manduca sexta|Rep: Sodium and chloride dependent proline transporter - Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm) Length = 556 Score = 405 bits (998), Expect = e-111 Identities = 202/506 (39%), Positives = 297/506 (58%), Gaps = 34/506 (6%) Query: 29 WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQ 88 W + ++ N+WRFPYLCY NGGGAFLIP+ + L+I G+PL+++E + GQ Sbjct: 9 WGSQLEYLLSCLGYAVGIGNLWRFPYLCYRNGGGAFLIPYFLTLIICGIPLVYLETTLGQ 68 Query: 89 YAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQ 148 +A+ G ++V+N PLF+G GY +++++ I +Y++ I+++ I Y+ S SS LPWQ Sbjct: 69 FASAGCISVFN-INPLFKGAGYAVIVLNVIASIYFSAIMSYPILYIYHSMSS---PLPWQ 124 Query: 149 NCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAEEYF 208 +C W+T +C NG+ IT P +EYF Sbjct: 125 SCGNSWNTVNCTEITGNSSFFTSNGS----------------ITT---------PEDEYF 159 Query: 209 TNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVI 268 +L +S I G I + C L W++V+LC+C GV+S GK+VYFT LFPYVVL + Sbjct: 160 HRHLLQVSPNINHIGSIVAPVFWCNLICWILVYLCICNGVKSVGKIVYFTVLFPYVVLSV 219 Query: 269 LFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFS 328 LF RG+TLPGA GI+FY+ PD++QLA +VW DAA QIFF+L P WGGL+++SS+NKF Sbjct: 220 LFVRGITLPGAWKGIMFYILPDWAQLAKPKVWADAATQIFFSLGPGWGGLVSMSSFNKFH 279 Query: 329 NNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVT 388 N S+I+ + N ATS +AG V+FSV+GF A NV V +V G GLAF+ YP VT Sbjct: 280 YNNLRSSMIIPIVNSATSIWAGFVVFSVLGFAAERTNVPVSQVATAGPGLAFVTYPATVT 339 Query: 389 RLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLG 448 +P LW+I FFVML LG+D+ F +E + +LD FP F+ +K + FI V + Sbjct: 340 MMPAPNLWAITFFVMLFFLGIDTMFVTIEAIIAGLLDEFPRFKSRKRIIAFITCVVLFSF 399 Query: 449 GLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLW 508 +I T G++ + L+D + A V ++ E +IA +Y E F D+ M GR + Sbjct: 400 SIICNTEGGLHVIGLLDSHVAILCVPLVCALE--IIAAVYTYENFSFDVLFMTGRPLR-- 455 Query: 509 VYLWSAMWRIITPAALVFILVFNWIE 534 +W +WR + L+ I +++ +E Sbjct: 456 -RIWMVLWRYVILLILLVITLYSLLE 480 >UniRef50_A4QNW3 Cluster: Transporter; n=10; Clupeocephala|Rep: Transporter - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 609 Score = 401 bits (987), Expect = e-110 Identities = 212/544 (38%), Positives = 320/544 (58%), Gaps = 40/544 (7%) Query: 16 APLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIA 75 A + ++ R W R +F NVWRFPYLCY +GGGAFLIP+ +ML + Sbjct: 44 AKVEQQAAEPRETWGRRLEFVLATIGYAVGLGNVWRFPYLCYRSGGGAFLIPYMIMLFLC 103 Query: 76 GLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMT 135 G+PL+FME + GQY LGPV + CPLF+G+G V++ S V+ Y Y Sbjct: 104 GIPLLFMEFTVGQYTRLGPVHALAQICPLFKGVGLATVVI-SYVLCTY---------YNV 153 Query: 136 VSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALA 195 + +++Y L +S+ + ++ N T+ N S N T L Sbjct: 154 LMTWALYYLL--------------HSFSPSLPWQSCNNTW--NTVANCSTGFPGNATHLQ 197 Query: 196 KTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVV 255 + +++F ++VL ++SGIE G +R + L+ AW IV+ C+ KGV+S+GKVV Sbjct: 198 SAS------QQFFDHKVLEMTSGIERAGGVRWELFGLLVLAWGIVYFCIFKGVKSTGKVV 251 Query: 256 YFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAW 315 YFTA FPY +L L V LPGA GILF+L P++S+L QVW +AA QIF ++ ++ Sbjct: 252 YFTATFPYFILFALLVNNVQLPGAKNGILFFLMPNWSKLLEVQVWVNAAAQIFNSIGISF 311 Query: 316 GGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQG 375 G +I+++SYNK++NN D+ IV+++N ATS AG VIFS IG++AH N+ VD + G Sbjct: 312 GSMISMASYNKYNNNILRDTFIVSLANSATSIVAGFVIFSAIGYMAHIHNLPVDDIATDG 371 Query: 376 AGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFP----NFR 431 GL F+VYPEV + +P+S LW+ LFF+MLL LGLDSQFA++E T I+D F Sbjct: 372 PGLVFVVYPEVFSTMPVSQLWAPLFFIMLLCLGLDSQFAMVEVAVTFIMDGFGRKALKVF 431 Query: 432 QKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAE 491 ++K +V V FG+L G+ T G+Y QLMD Y A S++ +A E + + I+G + Sbjct: 432 KRKELIVLAVCSFGFLLGIPHITRGGIYVFQLMDHYTAVVSLMFLAFFEVLAVTLIFGVK 491 Query: 492 KFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYG-HYVYPMWAD 550 + ++ M+G++ L+ + W+ ++P ++ IL+ + ++Y PA YG Y YP+WA+ Sbjct: 492 RLSVMVENMLGKKPNLF---FRICWQYLSPMLVLGILISSIVQYTPARYGKSYTYPLWAE 548 Query: 551 AVGW 554 +GW Sbjct: 549 LLGW 552 >UniRef50_Q0PKT4 Cluster: High-affinity octopamine transporter; n=1; Lumbricus terrestris|Rep: High-affinity octopamine transporter - Lumbricus terrestris (Common earthworm) Length = 673 Score = 400 bits (986), Expect = e-110 Identities = 217/560 (38%), Positives = 311/560 (55%), Gaps = 44/560 (7%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 R W + DF NVWRFPYLCY NGGGAFLIP+ ML+ +PL MEL Sbjct: 108 RETWNKKADFLLSIIGFAVDLANVWRFPYLCYTNGGGAFLIPYFTMLICGAVPLFLMELI 167 Query: 86 FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQL 145 GQY G + V+ K PLF+G+G +++ V YYN+IIAW+++Y+ SF+ Y L Sbjct: 168 MGQYQRQGAITVW-KIAPLFKGIGICQCLIAFYVAFYYNVIIAWSLYYLVSSFA---YVL 223 Query: 146 PWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAE 205 PW C W+T +C D NG S S+ T TA A Sbjct: 224 PWTTCNNTWNTMNCI-----DGSAMANG------------STSNEST----TA-----AA 257 Query: 206 EYFTNQVLGL--SSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPY 263 E+F VLGL SSGI + G R + +CL +++++ L KGV SSGKVV+ TA PY Sbjct: 258 EFFERGVLGLQESSGIGDIGLPRKYLVLCLFGVFIMIYFSLWKGVHSSGKVVWVTATMPY 317 Query: 264 VVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSS 323 VVL IL RG+ LPGA GI++Y+TP +L + +VW DAA+QIF+++ +G I +S Sbjct: 318 VVLSILLVRGLMLPGASIGIMYYITPKLERLGDPKVWIDAAIQIFYSVGAGFGVHIAFAS 377 Query: 324 YNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVY 383 YNK ++NCY D L N TS F+G VIFS +G+++ + V +G GL F+VY Sbjct: 378 YNKINSNCYRDCLATVCVNSFTSLFSGFVIFSYLGYMSIRQKKDISVVAAEGPGLVFVVY 437 Query: 384 PEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNF--RQKKGWVVFI- 440 PE + LP S WSILFFVML+TLG+DS +E + T + D + + R + G Sbjct: 438 PEAIATLPGSVGWSILFFVMLITLGIDSAMGGLEALLTGLSDEWKSVIKRYRFGREALTG 497 Query: 441 VAVFG-YLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQR 499 + VFG +L L TN GMY + + D++AA ++L + + ++W YG E+FC D ++ Sbjct: 498 MVVFGAFLFALPNVTNGGMYLVTIWDRFAAGTAILFGVFSQAVAVSWFYGMEQFCKDAEQ 557 Query: 500 MIGRQSKLWVYLWSAMWRIITPAALVFILV-----FNWIEYKPASYGHYVYPMWADAVGW 554 ++G + L+ W W+ I+P ++ I++ F +EYK + G+Y +P+WA+ VGW Sbjct: 558 ILGFRPNLY---WRLTWKFISPIFILGIVISSVVSFEPLEYKTYTMGNYTFPVWANVVGW 614 Query: 555 TXXXXXXXXXXXXXXDQICS 574 Q+CS Sbjct: 615 GIALSSMSFIPIVAVYQLCS 634 >UniRef50_O76689 Cluster: Sodium-dependent acetylcholine transporter; n=2; Caenorhabditis|Rep: Sodium-dependent acetylcholine transporter - Caenorhabditis elegans Length = 714 Score = 397 bits (977), Expect = e-109 Identities = 185/575 (32%), Positives = 323/575 (56%), Gaps = 10/575 (1%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 RGNW+ + D+ + W+FP+L + +GG AFL+P+ ML +A LP+ FME+ Sbjct: 64 RGNWSNKSDYLLAVIGFTAGVGSFWKFPFLVFQHGGAAFLVPYLCMLCLASLPMFFMEMV 123 Query: 86 FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQL 145 GQ+++ ++V+ K PLF+G+G+ V +S +++N+I AWT+FY+ SFS + + Sbjct: 124 LGQFSSSAAISVW-KVVPLFKGIGFAQVTISGFFAVFFNIISAWTLFYLINSFS---FSI 179 Query: 146 PWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAE 205 PW NC WS ++C + +C+ NGT + ++ S+ T + L P+ Sbjct: 180 PWSNCANSWSGENC-TLGTRIQCKEMNGTLLVNGSCIVEHASSNETTVIPLHDLGSIPSL 238 Query: 206 EYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVV 265 +YF N VL LS G+++ G + + +C+LA W+ VFLCL +GV+SSGKVVY + P+++ Sbjct: 239 KYFQNDVLMLSKGVDDFGTLNWYLGLCVLACWIAVFLCLFQGVKSSGKVVYVAVIVPFII 298 Query: 266 LVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYN 325 L +L R +TL G++ + ++LTP + L + VWG+AAVQ F+++S GGL T++SY+ Sbjct: 299 LTVLLTRLLTLDGSLAAVFYFLTPKWEILMDLHVWGEAAVQAFYSVSCCSGGLFTIASYS 358 Query: 326 KFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRV-VDQGAGLAFIVYP 384 +F NN Y D +V + ++ S L+ FS IGF +E +S+D+ + G L F+ Sbjct: 359 RFHNNIYKDIWLVLIVDVIVSLVGCLLTFSAIGFTCYEFAISLDKFHIRDGFHLVFVFLA 418 Query: 385 EVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFP-NFRQKKGWVVFIVAV 443 E + + ++PL++ LFF+M+L + +Q ++ET+ ++I D +P R+ + V+ V Sbjct: 419 EALAGVSVAPLYAGLFFIMILLVVHATQMFVVETIVSSICDEYPERLRRNRRHVLTTVCA 478 Query: 444 FGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGR 503 L + F +SG++W++L+ ++ W +++IA EC+ I W+YG + + + ++G Sbjct: 479 LFILLSIPFCLSSGLFWMELLTQFVLTWPLVVIAFLECMAINWVYGVDNMLDNAKWIVGY 538 Query: 504 QSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGWTXXXXXXXX 563 +++ W +++ I P + IL F W+++ Y Y +P W+ W Sbjct: 539 WPPCYIF-WKILFKFICPMVYLAILCFLWLDWNSIQYESYQFPYWSILTAWCIASFPLIL 597 Query: 564 XXXXXXDQICSGPDDLTIMEKARVLARPTEEWGQA 598 Q C TI +K + P + WG A Sbjct: 598 IPIVGIWQFCIAKG--TITQKWWRVLYPDDAWGPA 630 >UniRef50_Q9VR07 Cluster: Sodium- and chloride-dependent GABA transporter ine; n=7; Endopterygota|Rep: Sodium- and chloride-dependent GABA transporter ine - Drosophila melanogaster (Fruit fly) Length = 943 Score = 393 bits (967), Expect = e-108 Identities = 208/554 (37%), Positives = 317/554 (57%), Gaps = 40/554 (7%) Query: 10 DEEKSKAPLSEE---IEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLI 66 D++ S +S+E ++P + +W + F NVWRFPY+CY +GGG FL+ Sbjct: 318 DDDDSYLDMSDETAQLKPRQQHWANKMQFVLACIGYSVGLGNVWRFPYMCYKSGGGVFLV 377 Query: 67 PFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLI 126 P+ ++L I +PL+FMELS GQY GP+ + CPLF+G G V+VS ++ YY++I Sbjct: 378 PYCIILFICSIPLLFMELSVGQYTGRGPIGALGQLCPLFKGAGLASVVVSFLMSTYYSVI 437 Query: 127 IAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYS 186 I ++I+Y F+S ++P W +C N + C+ Sbjct: 438 IGYSIYYF---FTSFKTEMP-------WI-----------DC---NNRWNTPDCWVPQRK 473 Query: 187 VSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCK 246 I A A R P+EE+F N+VL +S G+E G +R + CL+ AW++V+ K Sbjct: 474 ---GINASAPDT-SRTPSEEFFENKVLQISGGLEYPGMMRWELFACLICAWLMVYFATWK 529 Query: 247 GVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQ 306 ++SS KV YFTA FP+V+++IL R VTL GA G+ F+ P +S+L NA VW +AA Q Sbjct: 530 SIKSSAKVRYFTATFPFVLIIILMVRAVTLDGAAEGLRFFFRPKWSELKNANVWINAASQ 589 Query: 307 IFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNV 366 F +L +G +I+ +SYNK++NN D++ V+ N+ TS G+ FS +G LA E N Sbjct: 590 NFNSLGITFGSMISFASYNKYNNNILRDTVAVSAVNMITSLLVGIFAFSTLGNLALEQNT 649 Query: 367 SVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDR 426 +V V+ G G+ F+VYP+ + ++P + LW+++FF MLL LGL+SQFA++E V T+I D Sbjct: 650 NVRDVIGDGPGMIFVVYPQAMAKMPYAQLWAVMFFFMLLCLGLNSQFAIVEVVVTSIQDG 709 Query: 427 FPNF-RQKKGW---VVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECI 482 FP + ++ G+ VV V V L G+ G+Y+ QLMD YAA+ +++ +A + I Sbjct: 710 FPRWIKRHLGYHEIVVLFVCVISCLFGMPNIIQGGIYYFQLMDHYAASVTIMFLAFCQMI 769 Query: 483 LIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASY-- 540 IAW YG + ++++M G+ YL S W ++ P L I V + I Y +Y Sbjct: 770 AIAWFYGTGRLSKNVKQMTGKAPSF--YLRSC-WLVLGPCLLFAIWVLSLINYHEPTYHN 826 Query: 541 GHYVYPMWADAVGW 554 G Y YP WA +GW Sbjct: 827 GRYTYPDWAYGIGW 840 >UniRef50_O17372 Cluster: Sodium:neurotransmitter symporter family protein 3; n=2; Caenorhabditis|Rep: Sodium:neurotransmitter symporter family protein 3 - Caenorhabditis elegans Length = 600 Score = 388 bits (954), Expect = e-106 Identities = 201/552 (36%), Positives = 310/552 (56%), Gaps = 28/552 (5%) Query: 7 LKGDEEKSKA--PLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAF 64 L DE K+K EP+RG WTG+FDF NVWRFPYLCY NGGG+F Sbjct: 9 LPTDEAKAKELEQSQHSEEPDRGQWTGKFDFLMSMVAYAVGLGNVWRFPYLCYKNGGGSF 68 Query: 65 LIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYN 124 L+ + + +A +P+ ME++ GQY G + ++ CPLFRG+G G V+++ + + Y+ Sbjct: 69 LVVYMIFFCLAAVPIFLMEVTVGQYLQKGAMEMW-LMCPLFRGVGIGNVVIAFMCIAYFC 127 Query: 125 LIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQS 184 +I+AW +FYM SSI + PW+ C W+ C + +E N T R + Sbjct: 128 VIVAWAMFYM---ISSIAWVFPWETCNNYWNDATCVTGKE-------NFTELARIKALVA 177 Query: 185 YSVSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCL 244 + H T++ E+++ +VL + I E G I+ + + AAW+IV+ L Sbjct: 178 SAGGHTQTSV----------EQFWEKRVLHDTGDISEFGGIQWELFFIMAAAWLIVYFAL 227 Query: 245 CKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAA 304 KG+ + K VYF ALFPYV++ IL RG+TL GA TGI FYL P+ ++L + VW DA Sbjct: 228 WKGITQARKFVYFCALFPYVLIFILLIRGLTLEGAGTGIYFYLKPNATRLLDTAVWKDAG 287 Query: 305 VQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHEL 364 Q+F++ +G LI L S+NKF++NC+ D++ + N TS AG +FS++G+++H Sbjct: 288 TQVFYSYGVGFGALIALGSHNKFNHNCFKDAITMCFINGCTSITAGFAVFSILGYMSHVA 347 Query: 365 NVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAIL 424 + +V G GLAF+ YPEV + LP+ ++++LFF+M+ LGLDSQ +ME + TA+ Sbjct: 348 QKDISEIVKPGVGLAFLAYPEVASNLPMKQVFAVLFFLMITILGLDSQVCMMEGLFTALE 407 Query: 425 DRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKY-AANWSVLIIAIGECIL 483 D FP R+ K + I +F + G+ T+SG +WL L D Y A+ +++L + E + Sbjct: 408 DAFPILRKYKKQSLGIFCLFFFCIGIPMVTHSGSHWLTLFDAYGASGYALLFVVFFEVVG 467 Query: 484 IAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASY-GH 542 +A+ +GA + MIG + +W+ PA + + VF + Y P Y Sbjct: 468 LAYGFGAHNIRKALHEMIGVTLPKGI---EYVWKFCAPATSLVLFVFCVVYYHPVKYPDG 524 Query: 543 YVYPMWADAVGW 554 +P WA+A GW Sbjct: 525 KDFPFWANAFGW 536 >UniRef50_Q7K330 Cluster: Transporter; n=11; Diptera|Rep: Transporter - Drosophila melanogaster (Fruit fly) Length = 654 Score = 384 bits (946), Expect = e-105 Identities = 198/576 (34%), Positives = 313/576 (54%), Gaps = 36/576 (6%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 +R +W +F NVWRFP+ NGGGAF+IP+ ++L++ G P+ ++E+ Sbjct: 73 KRDSWNNDIEFLMSCIALSVGLGNVWRFPFTALENGGGAFVIPYLIVLILVGKPVYYLEM 132 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 GQ+++ G V VY+ F P+ RG+GYG V+ + IV YY ++A T+ Y SF + Sbjct: 133 LLGQFSSRGSVKVYD-FSPIMRGIGYGQVLATGIVTTYYATLMALTLRYFVDSF---YPT 188 Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPA 204 LPW C+ EW T +C + + T+LA + +R A Sbjct: 189 LPWSYCREEWGT----------------------ECLDSGPQEASRATSLAGSGVRTTSA 226 Query: 205 EEYFTNQVLGLSSGIEE-TGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPY 263 E YFTN +L + I++ G +A+ L AW+++ + KGV+SSGK YF ALFPY Sbjct: 227 EFYFTNIILREKASIDDGIGYPSWSLALALAVAWIVIAGIMFKGVKSSGKASYFLALFPY 286 Query: 264 VVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSS 323 VV+++L R +TLPGA G+L++L P + +L QVW A Q+FF+L+ +G +I +S Sbjct: 287 VVMLVLLVRALTLPGAFDGVLYFLRPQWHKLLEPQVWYAAVTQVFFSLAICFGNIIMYAS 346 Query: 324 YNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVS-VDRVVDQGAGLAFIV 382 YN+F +N Y D+ IV + TS +G++IF ++G LA+E N + + VV+ G GLAFI Sbjct: 347 YNRFGHNIYRDANIVTTLDTFTSLLSGVIIFGILGNLAYENNTTDIASVVNGGPGLAFIS 406 Query: 383 YPEVVTRLPISP-LWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFI- 440 YP+ + + P L+S+LFF+ML LG+ S + ++T I D+F + K W V + Sbjct: 407 YPDAIAKFKWLPQLFSVLFFLMLFVLGIGSNVGMASCMSTVIKDQFGHL---KNWTVVVG 463 Query: 441 VAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRM 500 +A+ GY GL++ T G + L L+D + + L++AI E + IAWIYG ++ C D++ M Sbjct: 464 IAIVGYFLGLLYITPGGQFLLNLVDYFGVTFVALVLAIFELVTIAWIYGVKRLCRDVEFM 523 Query: 501 IGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGWTXXXXX 560 IG ++ L+ + W ++TP ++ IL++ + Y+P Y Y Y GW Sbjct: 524 IGIKTSLY---YRICWAVVTPLLMLTILIYTLVLYEPLKYKDYTYQSGVYVFGWCLSAFG 580 Query: 561 XXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWG 596 + P L + + R P WG Sbjct: 581 VGQVLFWAIPAVRKQPSHLGLWARIRKAFEPLPNWG 616 >UniRef50_Q9W4C5 Cluster: Uncharacterized sodium-dependent transporter CG3252; n=9; Endopterygota|Rep: Uncharacterized sodium-dependent transporter CG3252 - Drosophila melanogaster (Fruit fly) Length = 641 Score = 384 bits (946), Expect = e-105 Identities = 205/583 (35%), Positives = 312/583 (53%), Gaps = 18/583 (3%) Query: 19 SEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLP 78 +E+ ER NW +F NVWRFP+ Y NGGGAFLIP+ ++L + G P Sbjct: 31 AEKPTAERTNWGNGLEFLMSCISVSVGLGNVWRFPFTAYENGGGAFLIPYIIVLFLIGKP 90 Query: 79 LMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSF 138 + ++E+ GQ+ + G V +++ P F G+GYG + ++ YY+ ++A T++Y+ VSF Sbjct: 91 MYYLEMIMGQFTSQGTVKIWS-VVPGFVGVGYGQAFGTICIISYYSSLLALTLYYLFVSF 149 Query: 139 SSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTA 198 S +LPW C+ EW+ +C + + + L N+S I A +T Sbjct: 150 QS---ELPWSYCRDEWT--NCVNSRPQEYVDNLLTGVSLA---NESARNLSGIVANDETE 201 Query: 199 LRRPPAEEYFTNQVLGLSSGIEE-TGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYF 257 + +E YF N V+ I + G+ + + L AWV++FL + +GV+SSGK YF Sbjct: 202 KLQSSSELYFLNVVIKEKLDISDGVGDPDWKLTLALFVAWVVIFLVIMRGVKSSGKAAYF 261 Query: 258 TALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGG 317 ALFPYVVL +L R VTL GA GILF+L P + +L N VW +A VQ FF+L+ G Sbjct: 262 LALFPYVVLFVLLIRAVTLEGARDGILFFLEPQWGELLNPTVWKEAVVQCFFSLAVGSGP 321 Query: 318 LITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNV-SVDRVVDQGA 376 +I +SYN+F + Y D++IV + TS G+ IF+++G LAH L + ++ VV G Sbjct: 322 IIMFASYNRFDHGIYRDAMIVTTLDTLTSLLGGITIFAILGNLAHNLQIENIRDVVRSGT 381 Query: 377 GLAFIVYPEVVTRLPISP-LWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKG 435 GLAFI YP+ +++ P L+S+LFF ML LG+ S AL T+ T I D+F ++ K Sbjct: 382 GLAFISYPDAISKFQAVPQLFSVLFFFMLFVLGIGSIVALQSTIVTIICDQFKGWKYWK- 440 Query: 436 WVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCG 495 V +V G+L GL++ T G + L L+D Y + V I+AI E I W+YG + FC Sbjct: 441 -VALTTSVCGFLMGLVYVTPGGQWILTLVDFYGGTYVVFILAIFELAGIVWVYGLQNFCD 499 Query: 496 DIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGWT 555 DI+ M R+ L+ W W TP ++ I +++ + +P Y +P A+ GW Sbjct: 500 DIEFMCNRRVSLY---WRVCWSFFTPVMMIIIFIYSMVTIEPIKYSELYFPEAANIAGWL 556 Query: 556 XXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWGQA 598 I P T + + +P++ WG A Sbjct: 557 LFAIGAAQFPLWGLWYISRHPQG-TYWKSLKASLKPSDRWGPA 598 >UniRef50_UPI00015B40E0 Cluster: PREDICTED: similar to glycine transporter; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to glycine transporter - Nasonia vitripennis Length = 584 Score = 378 bits (931), Expect = e-103 Identities = 200/472 (42%), Positives = 283/472 (59%), Gaps = 41/472 (8%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 +R W +F NVWRFPYL Y NGGGAFLIPF +ML+ GLP+ F+EL Sbjct: 34 QRQGWANPLEFVLSCIGYAVGIGNVWRFPYLVYRNGGGAFLIPFVLMLLTMGLPIFFLEL 93 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 GQY LGP Y + P F+GLGY ++V ++V +YY +II+WT+FY SFSS + Sbjct: 94 IVGQYVGLGPTEAYARMAPAFQGLGYCTIVVIALVTIYYMVIISWTLFYTFASFSS---K 150 Query: 145 LPWQNCKAEWS--------------TKHCYSYEEADECEAQNG--TYYLRQC-----FNQ 183 L W C E++ T HCYS + EC A+ YY R C F + Sbjct: 151 LAWAYCDNEFNSPSERRHLRSSMLITCHCYSSLQDAECRAERPDLVYYNRSCMGIEAFCR 210 Query: 184 SYSVSHNIT---------------ALAKTALRRPPAEEYFTNQVLGLSSGI-EETGEIRL 227 S+ ++ N++ L R +EE++ + VLG+ E+ G +R Sbjct: 211 SFGLASNLSDPTHCYKVGGNGPGIELRHLYNRTLSSEEFYNDYVLGIRDAKWEDWGGMRW 270 Query: 228 GMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYL 287 + C+ AW++ +LCL KG+QS GKVVYFTALFPY VL+ RG TL GA+ GIL+Y+ Sbjct: 271 ELLGCISLAWLVCYLCLIKGIQSVGKVVYFTALFPYFVLIAFMIRGATLEGAVDGILWYI 330 Query: 288 TPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSF 347 +P +S L +A+VW DAA Q+F++L G L+TL+SY+ FSNNC+ D++ V ++N+ TS Sbjct: 331 SPRWSYLMDARVWADAASQVFYSLGIGCGSLVTLASYSSFSNNCHRDAVFVTLTNLLTSV 390 Query: 348 FAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTL 407 FAG V FSV+GFL +++N+ ++ VV GLAFIVYPE V ++P+S LW++LFF+ML L Sbjct: 391 FAGFVTFSVMGFLMNQMNLPIEEVVRSETGLAFIVYPEAVVQMPLSNLWAVLFFLMLFIL 450 Query: 408 GLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMY 459 GL SQFA ++ ++ AI+D P+ R + V+ +V VF Y T + G Y Sbjct: 451 GLGSQFAGVQAISCAIMDVRPDLRPHESRVI-LVGVFIYQMYTYRTASFGDY 501 Score = 40.3 bits (90), Expect = 0.15 Identities = 20/80 (25%), Positives = 35/80 (43%), Gaps = 7/80 (8%) Query: 524 LVFILVFNWIEYKPASYGHYVYPMWADAVGWTXXXXXXXXXXXXXXDQICSGPDDLTIME 583 LV + ++ Y+ AS+G Y +P+WAD +G + GP D +++ Sbjct: 482 LVGVFIYQMYTYRTASFGDYKFPVWADVIGILIGLSTLAPMPIFFCYHLWRGPRDWSLL- 540 Query: 584 KARVLARPTEEWGQAGSTAT 603 +P+ WG A +T Sbjct: 541 ------KPSSSWGPAKKAST 554 >UniRef50_UPI000069E376 Cluster: Orphan sodium- and chloride-dependent neurotransmitter transporter NTT4 (Solute carrier family 6 member 17).; n=4; Xenopus tropicalis|Rep: Orphan sodium- and chloride-dependent neurotransmitter transporter NTT4 (Solute carrier family 6 member 17). - Xenopus tropicalis Length = 535 Score = 378 bits (930), Expect = e-103 Identities = 194/534 (36%), Positives = 292/534 (54%), Gaps = 32/534 (5%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 +R W + + NVWRFPYLC NGGGA+++P+ ++L+I G+PL F+EL Sbjct: 3 DRPAWNNKLQYILAQIGYSVGLGNVWRFPYLCQKNGGGAYMVPYLILLIIIGIPLFFLEL 62 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 + GQ G + V+N CP G+GY +V V LYYN+II W+IFY F S Y Sbjct: 63 AVGQRIRRGSIGVWNYICPRLGGIGYASCVVCFFVGLYYNVIIGWSIFYF---FQSFQYP 119 Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPA 204 LPW C +NG+ + + H + + + Sbjct: 120 LPWNECPT-----------------VKNGSAIYQSSWTNICFCIHTVLVVEAECDKSSAT 162 Query: 205 EEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264 ++ + L +S+ I E G + M +CLL AW +V + + KG+QSSGKV+YF++LFPYV Sbjct: 163 TFFWYREALDISNSISEGGGLNWKMTLCLLVAWTMVCMAMIKGIQSSGKVMYFSSLFPYV 222 Query: 265 VLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSY 324 VL+ RG+ L G++ GIL LTP ++ + QVW +AA Q+FFAL +GG+I SSY Sbjct: 223 VLICFLIRGLFLRGSVDGILHMLTPKVEKMLDPQVWREAATQVFFALGLGFGGVIAFSSY 282 Query: 325 NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAH-ELNVSVDRVVD--QGAGLAFI 381 NK NNC D+ +V+ N TS A LV+F+V+GF A+ + N + + QG GLAFI Sbjct: 283 NKQDNNCQFDAALVSFINFFTSVLATLVVFAVLGFKANFKYNPGLGLYTEAVQGTGLAFI 342 Query: 382 VYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNF----RQKKGWV 437 + E +T P SP WS++FF ML+ LGL S M + T I+D F +++ V Sbjct: 343 AFTEAMTHFPASPFWSVMFFFMLINLGLGSMIGTMSGIITPIIDTFKCLTSWSNEREHTV 402 Query: 438 VFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDI 497 + +L GLIF SG Y++ + D Y+A + I+ I E I +AW+YG +KF ++ Sbjct: 403 HCSCCIVAFLLGLIFVQRSGNYFVNMFDDYSATLPLTIVVILENIAVAWVYGTKKFMQEL 462 Query: 498 QRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKP--ASYGHYVYPMWA 549 M+G + + Y +S W+ ++P + +L + I++ P A+ +YP WA Sbjct: 463 TEMLGFRPYSY-YFYS--WKYVSPIFMAILLTASVIQFAPFQAAEQFVLYPTWA 513 >UniRef50_Q4S8W1 Cluster: Transporter; n=2; Tetraodontidae|Rep: Transporter - Tetraodon nigroviridis (Green puffer) Length = 629 Score = 376 bits (926), Expect = e-103 Identities = 225/556 (40%), Positives = 317/556 (57%), Gaps = 89/556 (16%) Query: 60 GGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIV 119 G FLIP+ +ML G+PL MELS GQY A GP+ V+ K CPL +G+G GM+ VS++V Sbjct: 84 GQRVFLIPYFIMLFFTGVPLFLMELSLGQYGAAGPIMVW-KCCPLLKGIGIGMLCVSTLV 142 Query: 120 MLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQ 179 LYYN+IIAWT +Y+ SF S LPW +C A + C A NG+ Sbjct: 143 CLYYNVIIAWTFYYLGSSFQS---PLPW-SCDAVANAGLC------GNSTAGNGS----- 187 Query: 180 CFNQSYSVSHNITALAKTALRRPPAEEYFTNQVLGL--SSGIEETGEIRLGMAMCLLAAW 237 + S S + +A+ + +VLG+ S G+ + G +R +A+CLLAAW Sbjct: 188 --GRILSPSEIFWNDSSSAVG--------SERVLGVVNSEGLHDPGPVRWRLALCLLAAW 237 Query: 238 VIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANA 297 +++FLC+ KG++SSGKVVY TA FPY+VLV+L RG TL G++ G+ FYLTPD+ +L+NA Sbjct: 238 IVIFLCMLKGIRSSGKVVYVTATFPYLVLVVLIIRGATLEGSLQGVAFYLTPDWGRLSNA 297 Query: 298 QVWGDAAVQIFFALSPAWGGLITLSSYNKFSNN---C----------------------Y 332 QVW DAA QIF++L GGL++++SYN+F NN C + Sbjct: 298 QVWNDAASQIFYSLGIGVGGLLSMASYNRFDNNVIRCVRVLGAAGGSLPWLAFHPGGSPF 357 Query: 333 IDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVD------------------- 373 D+LI+ + N +TSFFAG IFS++G +A + V V V D Sbjct: 358 RDTLIITIGNCSTSFFAGFAIFSILGHMAWKKGVPVAEVADTGTPETFSQTVSLAVVLHL 417 Query: 374 -------QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDR 426 G GLAF+ YPE + LP S WSI+FF+ML LG+D+ F ME +TTA+LD Sbjct: 418 FLGGVFASGPGLAFVAYPEALALLPGSVFWSIMFFLMLFMLGVDTLFGNMEGITTAVLDE 477 Query: 427 FPNFRQK---KGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECIL 483 FP R K + + YL GL+ T+ G+YW L+D ++ ++ ++IIA+ C+ Sbjct: 478 FPQLRLNTVHKSLFLAALCFCFYLMGLLLVTDGGIYWFTLIDSFSTSFGLIIIALFMCLG 537 Query: 484 IAWIYGAEKFCGDIQRMIGR----QSKLWVYLWSAMWRIITPAALVFILVFNWIEY--KP 537 I++ YG +FC DI MI SK+ +Y + A W + TP L+FIL + +IE P Sbjct: 538 ISFFYGVNQFCQDIIDMICHCPPWCSKVLLY-FKACWIVFTPFLLLFILTYIFIEMYNTP 596 Query: 538 ASYGHYVYPMWADAVG 553 YG YVYP+W A+G Sbjct: 597 LRYGPYVYPLWGKALG 612 >UniRef50_UPI0000D56C9C Cluster: PREDICTED: similar to CG3252-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG3252-PA - Tribolium castaneum Length = 619 Score = 376 bits (924), Expect = e-102 Identities = 206/542 (38%), Positives = 297/542 (54%), Gaps = 31/542 (5%) Query: 17 PLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAG 76 P ++ E ER W +F N+WRFP+ Y NGGGAFLIP+ ++L + G Sbjct: 25 PENKGDERERAQWGNGLEFLMSCVAMSVGLGNIWRFPFTAYENGGGAFLIPYIIILTLIG 84 Query: 77 LPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTV 136 PL +ME+S GQ++ G + + P +G+GY VI + V YY ++A T+FY+ Sbjct: 85 RPLYYMEMSLGQFSNRGNIRFFKSLSPYLKGVGYAQVIGAGFVATYYCCLMAITLFYLVN 144 Query: 137 SFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAK 196 SF+ LPW CK EW + + ++ +QC + + S+N T Sbjct: 145 SFTG---DLPWSTCKEEWLA----------DLDKEH-----KQCVDAIATTSNN-TKANY 185 Query: 197 TALRRPPAEEYFTNQVLGLSSGIEE-TGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVV 255 TA+ +E YFT +VL + I + G + +CLLA+W+I FL KGVQSSGK Sbjct: 186 TAVSS--SEVYFTKEVLKEITDISDGIGTPEWRLTLCLLASWIITFLVSVKGVQSSGKAS 243 Query: 256 YFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAW 315 YF ALFPYV+++ L R TL GA G+ +++ D+++LA A VW A Q FF+L+ + Sbjct: 244 YFLALFPYVIMITLLIRAATLEGAADGMYYFIKTDWAKLAEADVWYAAVTQCFFSLNVGF 303 Query: 316 GGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQ- 374 G +I +SYN F +N D+LIV + TS +G IF ++G LAH + V+ D V+ Sbjct: 304 GSIIMFASYNNFEHNINRDALIVTTLDTFTSLLSGATIFGILGNLAHNMGVTPDLVIKSG 363 Query: 375 GAGLAFIVYPEVVTRLPISP-LWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK 433 G GLAFI YP+ + ++ P L++ILFF ML LG+ S AL TV T + D FP Sbjct: 364 GTGLAFISYPDAIAKMEAVPWLFAILFFFMLFVLGVGSLVALHGTVNTVVQDLFPKL--- 420 Query: 434 KGW-VVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEK 492 K W V A G+L GL++ T G + L L+D YA + + + A+ E +AW+YG E Sbjct: 421 KSWQVSAYTASGGFLIGLMYVTPGGQFMLNLVDHYAGTFLIFVFAVLEVAAVAWVYGLEN 480 Query: 493 FCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAV 552 FC D++ M + K+ VY W W +ITPA L I V+ + + SY Y YP A Sbjct: 481 FCLDLEFM--SKKKVSVY-WRMTWGLITPALLFIIFVYFCVRNERLSYASYPYPDGVLAF 537 Query: 553 GW 554 GW Sbjct: 538 GW 539 >UniRef50_UPI0000E4659C Cluster: PREDICTED: similar to GABA transporter; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to GABA transporter - Strongylocentrotus purpuratus Length = 691 Score = 375 bits (923), Expect = e-102 Identities = 206/534 (38%), Positives = 303/534 (56%), Gaps = 63/534 (11%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 +RG WTG+ DF NVWRFPYLCY NGGGAFL+P+ + L++AG+P+ E Sbjct: 122 KRGKWTGKMDFLLACIGYAIGLGNVWRFPYLCYRNGGGAFLLPYLLTLIVAGIPVFLFET 181 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 S GQ +LG + V+ K CPLF+G+GY V++S + ++Y ++IAW + Y+ SF+S + Sbjct: 182 SLGQLLSLGGLGVW-KICPLFKGVGYAAVVMSFWLNVWYIVVIAWALLYLANSFTS---K 237 Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPA 204 LPW HC N L NQ+ +++N T P Sbjct: 238 LPWS---------HC-----------DNDFNTLNCTTNQT--LANNYTT--------DPT 267 Query: 205 EEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264 E++ VL S GI + G++R +A+ LLAAW+I + C+ KGV+ +GKVVYFTAL+PYV Sbjct: 268 TEFWKQYVLEESDGIHQPGKVRWQLAVTLLAAWIICYFCIWKGVKWTGKVVYFTALYPYV 327 Query: 265 VLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSY 324 +L++LFFRGVTL GA GI++Y+ P+FS+L ++ VW DAA QIFF+ G LI L SY Sbjct: 328 MLIVLFFRGVTLEGAREGIIYYIKPNFSRLTDSGVWIDAATQIFFSYGTGIGSLIALGSY 387 Query: 325 NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYP 384 NKFSNN Y DS+IVA N TSFFAG V+FS +G LAH N V V G GL F+ YP Sbjct: 388 NKFSNNVYRDSMIVACVNTGTSFFAGFVVFSTLGHLAHVQNKDVADVATSGPGLTFLAYP 447 Query: 385 EVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQ-KKGWVVFIVAV 443 + +LP +W+++FF M+ +GLDSQ + + ++ + + R+ +K ++ A+ Sbjct: 448 AAIAQLPFPAVWAVMFFSMIFMVGLDSQVTMTTEIYNSLSSKPMSLRKPRKLFISNYFAL 507 Query: 444 FGYLGGLIFTTNSGMYWLQLMDKYAANW-SVLIIAIGECILIAWIYGAEK--FCGDIQRM 500 F L L + G+Y +L++ Y+++ S+L + + I ++W YG F G Q Sbjct: 508 FFPL-SLALPSQGGIYVFELLNTYSSSGISLLFLTFFQTIGVSWFYGNTPGYFGGASQHY 566 Query: 501 IGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGW 554 G + +F+ ++YK Y Y YP+W + +GW Sbjct: 567 SG------------------------VFLFSLVKYKRVEYEDYTYPVWGEVIGW 596 >UniRef50_UPI0000E4A90B Cluster: PREDICTED: similar to ENSANGP00000013630, partial; n=6; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to ENSANGP00000013630, partial - Strongylocentrotus purpuratus Length = 597 Score = 373 bits (917), Expect = e-101 Identities = 196/550 (35%), Positives = 300/550 (54%), Gaps = 33/550 (6%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 +R NW GRFDF N+WRFPYLCY NGGGAFL+P+ +L+ +PL+ +E Sbjct: 53 KRENWGGRFDFAISCLGYAVGLSNIWRFPYLCYKNGGGAFLVPYCTLLLFVCIPLIVLEF 112 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 + GQY++ V+ P+ RG+ Y ++ + YY ++I++ ++Y F+S+ Sbjct: 113 AIGQYSSSNFAKVWRAL-PIMRGIWYCQMLSYIVGNGYYGVVISYAVYYF---FASLTSH 168 Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLR-QCFNQSYS-----VSHNITALAKTA 198 LPW C +W+T +C E D+C Q+G C N + +N+T T Sbjct: 169 LPWVGCGHKWNTLYCS--ELFDDCLNQDGIIISNGSCANVTLLSDEELAGYNVTVFNDTF 226 Query: 199 L------------RRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCK 246 L R P+EEY+T SS IE+ G + +A+C L WV++FL + K Sbjct: 227 LDFSNYTDPIKNMRVLPSEEYWTE-----SSSIEKPGGVVWQLALCNLFVWVVIFLIIAK 281 Query: 247 GVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQ 306 G+++SGKVVYFTALFPYV++ L R +TL G + GI +++ P +S++ + W DAA Q Sbjct: 282 GIKTSGKVVYFTALFPYVMMTALLIRALTLDGYMDGIRYFVKPTWSKIVHPLPWKDAAQQ 341 Query: 307 IFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNV 366 +FF+ G L T++S+N F N D+LI+A+ N TS + G +F+++G++A ++ V Sbjct: 342 VFFSSGSGGGSLGTMASFNTFHNTFVNDALIMAIGNSLTSLYCGFAVFAILGYMAKQIGV 401 Query: 367 SVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDR 426 V VV G GL F+V P + + P +WS LFF M+ L LDSQF +E + T ILD Sbjct: 402 PVQEVVKGGFGLVFVVCPAALAKFPGRSVWSALFFGMIFLLALDSQFVCIEAMVTVILDA 461 Query: 427 FPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAW 486 P R+ + V + YL + TN+G YW+ L+D Y A W +I I I W Sbjct: 462 MPRLRRWRVLVCAFLCFGTYLTTFSYVTNAGPYWVALLDNYYAGWISMITGIAIPISFTW 521 Query: 487 IYGAEKFCGDIQRMIGRQS-KLWV-YLWSAMWRIITPAALVFILVFNWIEYKPASYGHYV 544 +YG ++ D++ M+G ++ W Y W W +TP LV + VF + P + Sbjct: 522 VYGFDRLKNDMRAMLGNKTVDHWTFYYWKISWMFLTPGILV-VSVFKHLTTFPGGIKEF- 579 Query: 545 YPMWADAVGW 554 + + DA+GW Sbjct: 580 HLVSDDALGW 589 >UniRef50_UPI0000EB09CC Cluster: UPI0000EB09CC related cluster; n=1; Canis lupus familiaris|Rep: UPI0000EB09CC UniRef100 entry - Canis familiaris Length = 516 Score = 371 bits (913), Expect = e-101 Identities = 199/539 (36%), Positives = 299/539 (55%), Gaps = 35/539 (6%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 ER W + + N+WRFPYLC GGGAFLIP+ + LV G+PL ++EL Sbjct: 1 ERPKWDNKLQYLLSCIGFAVGLGNIWRFPYLCQTYGGGAFLIPYLIALVFEGIPLFYVEL 60 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 + GQ G + V+ P G+G G V VS +V LYYN ++ W ++Y SF S Sbjct: 61 AIGQRLRRGSIGVWTAISPYLGGVGLGCVTVSFLVSLYYNTVLTWVLWYFLNSFQS---P 117 Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPA 204 LPW +C + + A G + +C S +VS+ Sbjct: 118 LPWSSCPLDVNRTGIGPTCCAWHSGGIPGPGFEAEC-QASSTVSY--------------- 161 Query: 205 EEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264 ++ Q L +++ I ++G I+ + CL A+W +V+LC+ +G++S+GK +YFTALFPY+ Sbjct: 162 --FWYRQTLNITADISDSGSIQGRLLACLAASWAVVYLCVIRGIESTGKAIYFTALFPYL 219 Query: 265 VLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSY 324 VL I RG+TLPGA+ G+++ TPD L N +VW DAA QIFF+LS A+GG I +SY Sbjct: 220 VLTIFLIRGLTLPGAVEGLIYLFTPDVQILQNPRVWLDAATQIFFSLSLAFGGHIAFASY 279 Query: 325 NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGF-LAHELNVSVDRVVDQGAGLAFIVY 383 N NNC D++ +A+ N TS +A + +FSV+GF A++ +DR G GLAFI++ Sbjct: 280 NPPRNNCEKDAVTIALVNSMTSLYASIAVFSVLGFKAANDHGRCLDRSA-SGTGLAFIIF 338 Query: 384 PEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQ-KKGWVVFIVA 442 E + +P +P W++LFF ML TLGL S F ME++ T +LD R K + + Sbjct: 339 TEAILHMPGAPGWAVLFFGMLFTLGLSSMFGNMESIITPLLDMGLTHRSIPKEVLTGLAC 398 Query: 443 VFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIG 502 + +L + FT SG YWL++ D YAA +++I A E I +A++YG ++F DI M G Sbjct: 399 LLCFLSAICFTLQSGNYWLEVFDNYAAPLNLIIFAFLEVIGVAYVYGLQRFSDDIVCMTG 458 Query: 503 RQSKLWVYLWSAMWRIITPAAL--VFILVFNWIEYKPASY----GHYVYPM--WADAVG 553 R+ L+ W W++++P L +F+ + + P SY YV P+ W +G Sbjct: 459 RRPSLY---WRVTWKVVSPLLLLTIFVAYIAVLVWTPLSYRAWNTQYVGPLGEWGATLG 514 >UniRef50_UPI0000DB6B93 Cluster: PREDICTED: similar to CG3252-PA; n=3; Apis mellifera|Rep: PREDICTED: similar to CG3252-PA - Apis mellifera Length = 625 Score = 370 bits (911), Expect = e-101 Identities = 204/596 (34%), Positives = 307/596 (51%), Gaps = 37/596 (6%) Query: 8 KGDEEKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIP 67 +G+ +K+K +++I P R W G F NVWRFP+ Y NGGGAFLIP Sbjct: 29 RGNNQKTKEEDAKDI-PSRAEWGGGLQFLMACIATSVGLGNVWRFPFTAYENGGGAFLIP 87 Query: 68 FTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLII 127 + ++L+ G P F+E GQ+ + P +GLGYG + V+ YY ++ Sbjct: 88 YIIVLIFVGKPFYFLEALLGQFTNRSCAKTWG-MVPAMKGLGYGQAFAAFCVVTYYCSLM 146 Query: 128 AWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSV 187 T++Y+ SF S +LPW C+ EW Y + + N + L +N ++ Sbjct: 147 GLTLYYLVASFQS---ELPWSYCREEWKD---YCVDTVSKDNNLNRSASLLTIYNDTF-- 198 Query: 188 SHNITALAKTALRRPPAEEYFTNQVLGLSSGIEE-TGEIRLGMAMCLLAAWVIVFLCLCK 246 R AE YF VL IE G + +CL +W +F LC+ Sbjct: 199 -------------RSSAELYFRKIVLNEYESIENGIGTPSWQLTICLFVSWATIFCVLCR 245 Query: 247 GVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQ 306 G++S+GK VYF A+FPYV++ L R VTL GA+ GILF +TPD+ +L VW A Q Sbjct: 246 GIKSTGKAVYFLAIFPYVIMTGLLIRSVTLEGAVNGILFLVTPDWDKLWQPNVWYAAITQ 305 Query: 307 IFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHEL-N 365 FF+LS +G ++T SSYN F + D LIV + TS AG IF ++G LAHEL N Sbjct: 306 CFFSLSVCFGPILTYSSYNNFQHGVSRDVLIVTTLDTFTSLIAGCTIFGILGNLAHELGN 365 Query: 366 VSVDRVVDQGAGLAFIVYPEVVTRLPISP-LWSILFFVMLLTLGLDSQFALMETVTTAIL 424 + +VV G GLAFI YPE +++ P L+++LFF+M+ LG+ S AL + + Sbjct: 366 ADISKVVRGGTGLAFISYPEALSQFNFVPQLFAVLFFIMMFVLGVGSAVALCGAIFCILC 425 Query: 425 DRFPNFRQKKGW-VVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECIL 483 D FPN K W +VFIV+ FG+L L++ T G +++ L+D Y + +I+ + E I Sbjct: 426 DHFPN---TKHWQLVFIVSFFGFLVSLVYVTPGGQWFVTLVDYYGGTFVAIIVGVLEMIT 482 Query: 484 IAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHY 543 + WIYG F D++ M+G + + W W ITP ++ IL++ + Y+ +Y + Sbjct: 483 VFWIYGLSNFINDVEFMLGGRPS---FYWRLCWAFITPILMIVILIYTVVTYESPTYDNM 539 Query: 544 VYPMWADA--VGWTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEE-WG 596 +P +A +GW ++ +I+E + RP+EE WG Sbjct: 540 PFPDYAYGWFIGWFLLALALFVIAGCILQKMIQLRSS-SIIETVKAAFRPSEEKWG 594 >UniRef50_UPI0000DB6B91 Cluster: PREDICTED: similar to CG3252-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to CG3252-PA - Apis mellifera Length = 609 Score = 361 bits (889), Expect = 2e-98 Identities = 191/549 (34%), Positives = 298/549 (54%), Gaps = 29/549 (5%) Query: 8 KGDEEKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIP 67 K EE + EI+ ER W +F N+WRFP+ Y NGGG FLIP Sbjct: 8 KSCEESRCVEIGREIK-ERSKWNNEIEFLMSCIAISIGFGNIWRFPFTAYENGGGVFLIP 66 Query: 68 FTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLII 127 + ++L + G P+ +ME+ GQ+++ + V+N P F G+G+ ++ +M YY+ ++ Sbjct: 67 YIIVLFLVGKPIYYMEIILGQFSSSSSINVWN-VSPGFSGIGWSQFYCNTALMTYYSSLM 125 Query: 128 AWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSV 187 A T+F++ SFS+ +LPW C+ EW +C + N T ++ Q N+ Sbjct: 126 ALTLFFLIASFSA---ELPWAKCREEW-LDYCIDSSHQIDNNTSNITSFV-QLLNEKE-- 178 Query: 188 SHNITALAKTALRRPPAEEYFTNQVLGLSSGIEE-TGEIRLGMAMCLLAAWVIVFLCLCK 246 RR AE YF VL IE+ G + +CLL +W+ V L + Sbjct: 179 ------------RRSSAELYFLKVVLEEKDSIEDGIGLPSWKLTLCLLVSWISVILITSQ 226 Query: 247 GVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQ 306 GV+SSGK YF A+FPY++L L R VTL GA TGILF++TP++S+L VW A Q Sbjct: 227 GVKSSGKASYFLAIFPYIILFSLLIRAVTLDGAATGILFFVTPEWSKLFEPSVWYAAVTQ 286 Query: 307 IFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNV 366 FF+LS +G ++T SS+N F +N Y D LIV + TSF AG IF ++G LAH++ + Sbjct: 287 CFFSLSVCFGPILTYSSHNDFKHNLYRDVLIVTTLDTLTSFIAGCTIFGILGNLAHKMGL 346 Query: 367 -SVDRVVDQGAGLAFIVYPEVVTRLPISP-LWSILFFVMLLTLGLDSQFALMETVTTAIL 424 +++VV G GLAFI YP+ + + + P L+++LFFVM+ LG+ S ++ + ++ Sbjct: 347 EDINKVVKSGVGLAFISYPDAIAKFNVVPQLFAVLFFVMMFVLGVGSIVGMVSGLAHSLK 406 Query: 425 DRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILI 484 ++ PN + K +V + + I+ T G + L L+D Y ++ V +A E I Sbjct: 407 EKLPNVQMWK--IVLCICSISFAVSTIYVTPGGQFLLSLVDYYGTSFVVFFLASFEITAI 464 Query: 485 AWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYV 544 W+YG E F D++ M+ R++ + W W ++TP L+FI + + +P +YG Sbjct: 465 MWVYGIENFLNDVEFMLSRRTGSY---WRICWFLVTPFILLFIFFYTFATLQPLTYGEKE 521 Query: 545 YPMWADAVG 553 YP+ A A G Sbjct: 522 YPISAHAAG 530 >UniRef50_A1Z8V9 Cluster: Transporter; n=3; Drosophila melanogaster|Rep: Transporter - Drosophila melanogaster (Fruit fly) Length = 629 Score = 359 bits (884), Expect = 9e-98 Identities = 201/592 (33%), Positives = 304/592 (51%), Gaps = 38/592 (6%) Query: 8 KGDEEKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIP 67 +G+E E +R W+ +F NVWRFP++ NGGGAFLIP Sbjct: 39 EGEELTINCEAESESSGQRDQWSRGVEFLFSCIALSVGLGNVWRFPFIALENGGGAFLIP 98 Query: 68 FTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLII 127 + ++L++ G P+ ++E+ GQ+++ G + ++ P+ RG+ YG V +++ YY I+ Sbjct: 99 YVIVLLLIGRPVYYLEVIIGQFSSRGCIRAFD-MAPIMRGIAYGQVYSTALATTYYACIM 157 Query: 128 AWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSV 187 A TI Y+ SFS + LPW C EW K C A A N + ++ V Sbjct: 158 ALTIRYLVASFSEV---LPWTYCLVEWG-KSCV----ATGATAANDSSIVQ-------GV 202 Query: 188 SHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKG 247 S +T LR P E + LG S + +CLLA WVI+ L KG Sbjct: 203 SSAELFFTQTVLREP---ESLDDNGLGTPSW---------DLVLCLLATWVIIGTILSKG 250 Query: 248 VQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQI 307 ++SSGK YF ALFPYV++++L R VTLPGA GI+++L P +SQL N VW A Q+ Sbjct: 251 IRSSGKASYFLALFPYVIMIVLLIRAVTLPGAWQGIVYFLKPQWSQLLNPHVWYAAITQM 310 Query: 308 FFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNV- 366 FF+L+ +G L+ +S+N F+ N + D +I+ + TS AG +IF ++G LA E N Sbjct: 311 FFSLAICFGTLVMYASFNDFNKNVHKDVIIITTIDSLTSILAGCIIFGILGNLAFETNTK 370 Query: 367 SVDRVVDQGAGLAFIVYPEVVTRLPISP-LWSILFFVMLLTLGLDSQFALMETVTTAILD 425 + +VV GAGLAFI YPE + + P L+++LFF MLL LG+ S + V + D Sbjct: 371 DISQVVKGGAGLAFISYPEAIAKFKYLPQLFAVLFFFMLLVLGIGSNIGMASAVVNVVKD 430 Query: 426 RFPNFRQKKGWVVFIVA-VFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILI 484 RF + W++ + A + G+L GL++ T G + L L+D Y + L++AI E + + Sbjct: 431 RFTHLPH---WLLAVSASIIGFLCGLVYMTPGGQFVLNLVDFYGCTFIALVLAIAELLAV 487 Query: 485 AWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYV 544 WIYG ++ C DI+ M+ ++ + W W I+ P + +LV+ Y+P +Y Sbjct: 488 GWIYGVKRICSDIEFMLNVKTS---FYWRICWAIVAPGLMFLVLVYMLFSYEPLTYRGVQ 544 Query: 545 YPMWADAVGWTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWG 596 YP GW I P T K + +PT WG Sbjct: 545 YPPVYYMAGWIIWGLGVLQLPFWALVTIYQQPGK-TFGSKFGLAMQPTANWG 595 >UniRef50_Q4T2D0 Cluster: Transporter; n=3; Euteleostomi|Rep: Transporter - Tetraodon nigroviridis (Green puffer) Length = 563 Score = 359 bits (883), Expect = 1e-97 Identities = 180/429 (41%), Positives = 258/429 (60%), Gaps = 32/429 (7%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 R W+ + DF NVWRFPY+CY NGGGAFL+P+ +M + G+PL +MEL+ Sbjct: 1 RETWSKKVDFLLSVIGYAVDLGNVWRFPYICYQNGGGAFLLPYLLMALFGGVPLFYMELA 60 Query: 86 FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQL 145 GQ+ G ++++ CP+F+G+G+ + I++ + YYN I+AW ++Y+ SF S L Sbjct: 61 LGQFHHSGCISIWKHVCPIFKGIGFAICIIALYIAFYYNTIMAWALYYLLSSFQST---L 117 Query: 146 PWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAE 205 PW C W+T +C Y D N S+S S PAE Sbjct: 118 PWSTCTNSWNTANCNHYMSTDH--------------NVSWSNSST-----------SPAE 152 Query: 206 EYFTNQVLGL--SSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPY 263 E++ QVL + S G+ + G I +A+CLL + IVF + KGV++SGKVV+ TA FPY Sbjct: 153 EFYVRQVLQVHRSPGLHQLGSISWQLALCLLFIFTIVFFSIWKGVKTSGKVVWVTATFPY 212 Query: 264 VVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSS 323 +VL++L RG TLPGA G++FYL PD+ +L + VW DAA QIFF+L P +G L+ +S Sbjct: 213 LVLLVLLIRGATLPGAWRGVVFYLKPDWEKLLSTTVWIDAAAQIFFSLGPGFGVLLAFAS 272 Query: 324 YNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVV-DQGAGLAFIV 382 YN F NNCY D+LI + N TSF +G VIF+V+G++A VD V D G L FI+ Sbjct: 273 YNPFHNNCYKDALITSSVNCLTSFLSGFVIFTVLGYMAEMRQQDVDAVAKDAGPSLLFII 332 Query: 383 YPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPN-FRQKKGWVVFIV 441 Y E + +P + +SI+FF+M++ LGLDS FA +E V TA+LD +P+ Q++ +VF + Sbjct: 333 YAEAIANMPAATFFSIIFFLMIIMLGLDSTFAGLEGVITAMLDEYPHVLVQRREKLVFGL 392 Query: 442 AVFGYLGGL 450 YLG L Sbjct: 393 VCVCYLGAL 401 Score = 64.9 bits (151), Expect = 6e-09 Identities = 31/109 (28%), Positives = 57/109 (52%), Gaps = 5/109 (4%) Query: 447 LGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSK 506 LG G + ++L ++YA +V+ + + E I ++W YG ++FC D+Q M+G Sbjct: 431 LGWCRLLPQGGAFVVKLFEEYATGPAVITVVLLEVIAVSWFYGTKRFCNDVQVMLGFYPG 490 Query: 507 LWVYLWSAMWRIITPAALVFILVFNWIEYKP-ASYGHYVYPMWADAVGW 554 ++ W W I P L+FI++ +++ + P Y YP W +G+ Sbjct: 491 IF---WRVCWVAICPCFLMFIII-SFLAFPPEVRLFSYHYPPWTTVLGY 535 >UniRef50_A1L1P6 Cluster: Transporter; n=3; Danio rerio|Rep: Transporter - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 537 Score = 357 bits (878), Expect = 5e-97 Identities = 183/395 (46%), Positives = 256/395 (64%), Gaps = 17/395 (4%) Query: 175 YYLRQCFNQ----SYSVSHNITALA-KTALRRPPAEEYFTNQVLGL--SSGIEETGEIRL 227 YYL F S NI A KT + P+E ++ +VLG+ S+G+ + G +R Sbjct: 61 YYLGSSFQSPLPWSCDALQNIALCANKTNSTQSPSEVFWNEKVLGVVHSTGLSDPGPVRW 120 Query: 228 GMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYL 287 +A+CLLAAW+I+FLC+ KG+ SSGKVVY TA FPY VL++L RG TL G++ G+ FYL Sbjct: 121 PLALCLLAAWIIIFLCMLKGIHSSGKVVYLTATFPYFVLLVLIIRGATLEGSLDGVAFYL 180 Query: 288 TPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSF 347 TP + QLA+AQVW DAA QIF++L GGL++++SYNKF NN D++I+ + N +TSF Sbjct: 181 TPKWDQLADAQVWNDAASQIFYSLGIGVGGLLSMASYNKFDNNVIRDTIIITIGNCSTSF 240 Query: 348 FAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTL 407 FAG IFS++G +A + V VD+V D G GLAF+ YPE + LP S WSILFF+ML L Sbjct: 241 FAGFAIFSILGHMAFKKGVPVDKVADSGPGLAFVAYPEALALLPGSVFWSILFFLMLFML 300 Query: 408 GLDSQFALMETVTTAILDRFPNFRQK-KGWVVFI-VAVFG-YLGGLIFTTNSGMYWLQLM 464 G+D+ F ME + TA+LD FP R K +F+ V F YL GL+ T+ G+YW L+ Sbjct: 301 GVDTLFGNMEGICTAVLDEFPQLRSNLKHKTLFLAVLCFSFYLMGLLLITDGGIYWFTLI 360 Query: 465 DKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGR----QSKLWVYLWSAMWRIIT 520 D ++ ++ ++II + CI I++ YG +FC DI MI R +K+ +Y + A W + T Sbjct: 361 DSFSTSFGLIIITLFMCIGISFFYGVNQFCQDIVDMICRCPPWCTKMLLY-FKACWVVFT 419 Query: 521 PAALVFILVFNWIE-YKPA-SYGHYVYPMWADAVG 553 P L FIL + +IE Y+ + YG YVYP+W A+G Sbjct: 420 PFLLTFILTYIFIEMYRTSLRYGSYVYPIWGKALG 454 Score = 93.9 bits (223), Expect = 1e-17 Identities = 45/82 (54%), Positives = 57/82 (69%), Gaps = 5/82 (6%) Query: 71 MLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWT 130 ML G+PL MELS GQY A GP+ V+ K CPL +G+G GM+ VS++V LYYN+IIAWT Sbjct: 1 MLFFTGMPLFLMELSLGQYGAAGPITVW-KCCPLLKGIGIGMLCVSTLVCLYYNVIIAWT 59 Query: 131 IFYMTVSFSSIFYQLPWQNCKA 152 +Y+ SF S LPW +C A Sbjct: 60 FYYLGSSFQS---PLPW-SCDA 77 >UniRef50_Q17EZ6 Cluster: Sodium/shloride dependent amino acid transporter; n=5; Culicidae|Rep: Sodium/shloride dependent amino acid transporter - Aedes aegypti (Yellowfever mosquito) Length = 637 Score = 356 bits (875), Expect = 1e-96 Identities = 199/541 (36%), Positives = 299/541 (55%), Gaps = 45/541 (8%) Query: 18 LSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGL 77 ++++ P R W +F NVW+FPY NGGGAFLIP+ V+L + G Sbjct: 57 VAKKPSPVRDKWGKDVEFMLSCIAYSVGFGNVWKFPYTALKNGGGAFLIPYLVVLFLVGR 116 Query: 78 PLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVS 137 P+ ++E+ GQ+++ G V +Y+ P RG+G G I IVM YY I+A T Y+ S Sbjct: 117 PIYYLEMVMGQFSSRGVVKIYD-LSPAMRGIGVGQSIAMFIVMTYYTPILAITFRYLVAS 175 Query: 138 FSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKT 197 FS++ LPW C W +C + ++ Q N N + K Sbjct: 176 FSAV---LPWAKCDPSWP--NCVDSD------------FVGQIVN-------NASIKPKA 211 Query: 198 ALRRPPAEEYFTNQVLGLSSGIEE-TGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVY 256 + AE YF N V+ ++ + E G + +CLL AW+ V L KG++SSGK Y Sbjct: 212 S-----AELYFQNSVMHQNASLYEGLGLPDWKLVLCLLFAWLCVATILIKGIKSSGKASY 266 Query: 257 FTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWG 316 F A+FPYV+++ILF TL GA GI+F+LTP + QL N VW +A Q FF+LS +G Sbjct: 267 FLAIFPYVIILILFVHACTLDGAFNGIMFFLTPQWDQLLNVTVWYEAVTQCFFSLSVCFG 326 Query: 317 GLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHEL-NVSVDRVVDQG 375 G+I +S+N FSNN Y D++I++ + TS AG ++F VIG LA+ + VV G Sbjct: 327 GIIAYASFNNFSNNVYKDAIIISWLDTFTSIIAGCIVFGVIGNLAYVTEQQDIQAVVKSG 386 Query: 376 AGLAFIVYPEVVTRLPISP-LWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKK 434 AGL F+ YP+ + + P L+S LFF+ML +GL S + ++ TAI D+ P + K Sbjct: 387 AGLTFMTYPDAIAKFDWLPQLFSALFFLMLFIVGLGSNLGVTTSIVTAIKDQCP---ELK 443 Query: 435 GW-VVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKF 493 W VV VAV G+ G+++ T GM+ L ++D Y A + L A+ E +AWIYG ++ Sbjct: 444 NWQVVSAVAVAGFSFGIVYLTPGGMHLLDILDYYGAKYVTLTFAVLELATLAWIYGVDRI 503 Query: 494 CGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVG 553 C DI+ M+G ++ L+ W W ++TP V IL+ ++I+Y+ +V P+ + +G Sbjct: 504 CRDIKFMLGIETSLF---WRICWGVVTPLVTVAILLLSFIDYEA-----FVVPVGYNVLG 555 Query: 554 W 554 W Sbjct: 556 W 556 >UniRef50_Q4T523 Cluster: Transporter; n=6; Tetraodontidae|Rep: Transporter - Tetraodon nigroviridis (Green puffer) Length = 535 Score = 351 bits (864), Expect = 3e-95 Identities = 189/539 (35%), Positives = 290/539 (53%), Gaps = 34/539 (6%) Query: 62 GAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVML 121 G FL+P+ V+ GLPL +E GQY G V + K CPL G GY ++V + Sbjct: 1 GVFLLPYCFFAVLCGLPLFLLESVIGQYTQEGAVTCWKKLCPLSEGTGY-FILVIQLYSR 59 Query: 122 YYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCF 181 Y +++AW + Y+ F LPW C + W+T C + Q+G L Sbjct: 60 LYTIVLAWALLYIIYCFRD---PLPWATCSSPWNTDRCVDLSSVNLTAGQSGNVTLNV-- 114 Query: 182 NQSYSVSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVF 241 S N+T + T E++ QVL +S GIEE G+++ + +CLLA W+ + Sbjct: 115 -----TSGNLTTSSVT--------EFWERQVLSMSGGIEELGKVQWELLLCLLACWMSCY 161 Query: 242 LCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWG 301 C+ KGV+S+GKVVYFTA+FPYV+LVIL RG+TLPGA+ G+++YL PD S+LA+ QVW Sbjct: 162 FCIWKGVRSTGKVVYFTAIFPYVMLVILLIRGLTLPGALQGVVYYLYPDVSRLADLQVWM 221 Query: 302 DAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLA 361 DA Q+ F+ + G LIT SYNK +NNC DSL + + N TSF AG +FSV+GF+A Sbjct: 222 DACSQVLFSYGVSSGTLITFGSYNKLNNNCCRDSLWLCLLNSCTSFVAGFTVFSVLGFMA 281 Query: 362 HELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTT 421 + V + VVD + F+ + R+P LW+ + + L + QF+ +ET+T Sbjct: 282 QQQGVPISNVVD-SVQMCFVDLEKAFDRVPWRVLWTRVSELDPLLMCATCQFSGLETITA 340 Query: 422 AILDRFPNFRQKKGW-----VVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLII 476 A++D FP + ++ W +V +VF +L ++ T G+Y QL+D YAAN S ++ Sbjct: 341 AVIDLFPR-KMRRPWRREIFLVIFCSVF-FLVQILLVTEGGVYLFQLIDHYAANGSCIMF 398 Query: 477 -AIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEY 535 ++ C+++ W +GA+K C ++ + G + W + + WR TP + + I Y Sbjct: 399 GSVIHCVVVGWAFGADKICDAVEDITGHRP--WAF-YKLCWRYFTPLICTVCFICSLINY 455 Query: 536 KP-ASYGHYVYPMWADAVGWTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTE 593 + S YVYP WA ++GW ++C T+ ++ VL P + Sbjct: 456 QSLISSKGYVYPDWAYSLGWAMAWSSIVTVPIYAIVKLCLTKG--TLQQRLMVLWHPDD 512 >UniRef50_Q9VSV2 Cluster: Transporter; n=3; Sophophora|Rep: Transporter - Drosophila melanogaster (Fruit fly) Length = 629 Score = 350 bits (860), Expect = 8e-95 Identities = 191/542 (35%), Positives = 303/542 (55%), Gaps = 40/542 (7%) Query: 19 SEEIEPER---GNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIA 75 S E+ P+R NW +F NVWRFP+ NGGGAFLIP+ V+L + Sbjct: 41 SSELSPDRKARDNWGSSLEFLMSCIALSVGLGNVWRFPFTALENGGGAFLIPYLVVLFVV 100 Query: 76 GLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMT 135 G P+ +ME+ GQ+++ G V V++ F PL RG+GY ++ ++ YY ++A T+ Y Sbjct: 101 GKPIYYMEMLLGQFSSRGIVQVFD-FAPLMRGVGYAQLLALGVLATYYASVMALTLRYFF 159 Query: 136 VSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALA 195 SF+S +LPW C+ EW D C + +G L+ ++++S S + L Sbjct: 160 DSFAS---ELPWSFCREEW----------GDGCVSASGGQPLQGQLSRNFSSSTQL-YLQ 205 Query: 196 KTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVV 255 + L + E + +G SG +A+ L +W+ V L + +GV+SSGK Sbjct: 206 RIVLNETDSLE----EGIGYPSG---------SLALMLGISWLTVTLIIIRGVKSSGKAA 252 Query: 256 YFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAW 315 Y ALFPYVV+ IL R +TLPGA G++++LTP + +L QVW +A Q+FF+L+ + Sbjct: 253 YVLALFPYVVMFILLVRALTLPGAYDGVMYFLTPQWEKLLEPQVWYNAVTQVFFSLAVCF 312 Query: 316 GGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNV-SVDRVVDQ 374 G +I SSYN+F +N Y D+ IV + TS +G++IF ++G LAHE + VV Sbjct: 313 GVIIMYSSYNRFGHNVYRDANIVTTLDTFTSLLSGVIIFGILGNLAHESGTKDIASVVKA 372 Query: 375 GAGLAFIVYPEVVTRLPISP-LWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK 433 G GLAFI YP+ + + + P ++S+LFF ML LG+ S ++ + T + D+F N Sbjct: 373 GPGLAFISYPDAIAKFKMFPQVFSLLFFAMLFMLGVGSNVGMVSCIMTVLKDQFVNV--- 429 Query: 434 KGWVVFI-VAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEK 492 K W++ + ++V G+L GLI+ T G + + LMD + + L+ AI E I + WIYG ++ Sbjct: 430 KLWIIVVSLSVIGFLVGLIYITPGGQHIITLMDFHGVTFVSLVSAIFELIAVGWIYGTKR 489 Query: 493 FCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAV 552 C D + M+ ++ + + W I+TP ++ ILV++ + +P SY +P+ V Sbjct: 490 LCQDAEYMLNIKTSNY---YRICWSIVTPLVMLVILVYSLLTMRPLSYNGQEFPLVYRVV 546 Query: 553 GW 554 GW Sbjct: 547 GW 548 >UniRef50_Q4SBR4 Cluster: Transporter; n=8; Euteleostomi|Rep: Transporter - Tetraodon nigroviridis (Green puffer) Length = 672 Score = 347 bits (854), Expect = 4e-94 Identities = 182/436 (41%), Positives = 256/436 (58%), Gaps = 18/436 (4%) Query: 127 IAWTIFYMTVSFS-SIF--YQLPWQNCKAEWSTKHCYS-YEEADECEAQNGTYYLRQCFN 182 I W+ M + + S+F +LPWQ+C W+T+ C+S Y D T L Sbjct: 189 ILWSFDLMPLGVTRSLFCVQELPWQSCDNPWNTEKCFSNYSLTD-------TTNLTSAVT 241 Query: 183 QSYSVSHNITALAKTA--LRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIV 240 + + + A K LR T + LSSG+EE GE+R + L AWV+V Sbjct: 242 EFWEYGRHECAERKVGRMLRMLTCGVSSTRNMHQLSSGLEEPGELRWPLVGTLALAWVLV 301 Query: 241 FLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVW 300 + + KGV+ +GKVVYF+A +PY +L ILFFRGVTLPGAI GILFY+TPDF++L ++VW Sbjct: 302 YFSIWKGVEWTGKVVYFSATYPYFMLFILFFRGVTLPGAIDGILFYITPDFNKLIRSEVW 361 Query: 301 GDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFL 360 DAA QIFF+ G LI L SYN ++N+ Y DS+IV N TS FAG VIFS++GF+ Sbjct: 362 LDAATQIFFSYGLGLGSLIALGSYNTYNNDVYKDSIIVCCINSCTSMFAGFVIFSIVGFM 421 Query: 361 AHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVT 420 ++ V + G GLAF+ YP+ VT+LP+S LW+ILFF ML+ LGLDSQF +E Sbjct: 422 SYITKKPVQELAASGPGLAFLAYPQAVTQLPMSSLWAILFFSMLMMLGLDSQFCTVEGFI 481 Query: 421 TAILDRFP-NFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAAN-WSVLIIAI 478 TA++D +P R++K + IV ++ G T G+Y +L D Y+A+ +L + Sbjct: 482 TALMDEYPLLLRKRKKIFILIVCFISFIIGFSNITQGGLYVFKLFDYYSASGMCLLYLVF 541 Query: 479 GECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPA 538 E + I+W YGAE+F +I+ MIG + +W W W TP + + F+ IE P Sbjct: 542 FETVSISWFYGAERFYKNIEDMIGYRPCIW---WKLCWMFFTPLICLGVFTFSAIEMTPL 598 Query: 539 SYGHYVYPMWADAVGW 554 + G YVYP+W +GW Sbjct: 599 TLGKYVYPLWGQVIGW 614 Score = 132 bits (318), Expect = 4e-29 Identities = 59/125 (47%), Positives = 83/125 (66%), Gaps = 2/125 (1%) Query: 17 PLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAG 76 P EEI P+RG+W G+FDF NVWRFPYLC NGGGAFLIP+ + LV AG Sbjct: 35 PKKEEI-PDRGSWKGKFDFLLSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFMTLVFAG 93 Query: 77 LPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTV 136 +PL F+E S GQ+ ++G + V+ K P+ +G+G V++S + +YY +IIAW ++Y+ Sbjct: 94 IPLFFLETSLGQFTSVGGLGVW-KLMPMMKGVGIAAVVLSFWLNIYYIIIIAWALYYLFN 152 Query: 137 SFSSI 141 SF S+ Sbjct: 153 SFRSV 157 >UniRef50_Q620M8 Cluster: Transporter; n=2; Caenorhabditis|Rep: Transporter - Caenorhabditis briggsae Length = 696 Score = 342 bits (840), Expect = 2e-92 Identities = 178/547 (32%), Positives = 281/547 (51%), Gaps = 17/547 (3%) Query: 23 EPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFM 82 E ER + +F N+WRFP + NGG AFLIP+ + G P ++ Sbjct: 56 EEEREGFGNGVEFVLTCLGLAVGLGNIWRFPMRAFENGGSAFLIPYLSCAFLFGFPAVYF 115 Query: 83 ELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIF 142 E GQY P ++ + P G+G+ V V+++V +YY +I++W Y+ F F Sbjct: 116 EFLTGQYNGKSPPVIFRRVMPFLEGVGWMGVFVAALVAIYYIVIVSWISIYIVNIFRGDF 175 Query: 143 YQLPWQNCKAEWSTKH-CYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALR- 200 W C W+ C EC + + I A + Sbjct: 176 NI--WNKCDNPWNQMETCIDMLRQKECRVNHPPGWENATAKMIPEKMFFINGTCMDAKKF 233 Query: 201 -----RPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVV 255 E+YFT ++ S+G+ + I L + + WV+ L + KG + GK+ Sbjct: 234 DGIEMLSATEQYFTRNIIDPSTGLYDFSGINLPILAAMTICWVLTALGILKGAKIMGKIS 293 Query: 256 YFTALFPYVVLVILFFRGVTLPGAITGILFYL-TPDFSQLANAQVWGDAAVQIFFALSPA 314 Y + L PY ++V+LF RGVTLPGA G+ +Y PD+S++ + W +A Q+ F+LS Sbjct: 294 YVSVLLPYFIVVVLFVRGVTLPGASDGLYYYFGKPDYSKIFLTRTWTEALKQLCFSLSVG 353 Query: 315 WGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQ 374 GGLI+LSSY++ +NN + D+LIV + + S G +FS +GFLA++ V V VV Sbjct: 354 HGGLISLSSYSRKNNNVFKDALIVIIGDTVMSLVGGAAVFSTLGFLANQRGVQVPEVVKS 413 Query: 375 GAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKK 434 G LAF+VYPE +T++P+ LWS LFF+ML LG ++ AL++ + I D+ P +R+KK Sbjct: 414 GFSLAFVVYPEAMTQMPLPWLWSFLFFLMLFLLGASTEIALVDVFCSCIYDQSPKYRKKK 473 Query: 435 GWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFC 494 VV + F Y GL+F+TN+G+YW ++ D+YAA +S + +GE I++ ++YG Sbjct: 474 WVVVTVWCFFLYCIGLVFSTNAGLYWFEMFDEYAAGFSSVCAVVGELIVMMYVYGFRNVR 533 Query: 495 GDIQRMIGRQSK-----LWVYLW--SAMWRIITPAALVFILVFNWIEYKPASYGHYVYPM 547 DI M+G + + W +A W I P F++ +++ P + YP+ Sbjct: 534 NDITEMLGEPKNKCTKAIGPHSWYFTANWMGIAPVIAAFLVALSFLRDYPYNGDANKYPI 593 Query: 548 WADAVGW 554 D +GW Sbjct: 594 VFDILGW 600 >UniRef50_Q4RY29 Cluster: Transporter; n=2; Tetraodontidae|Rep: Transporter - Tetraodon nigroviridis (Green puffer) Length = 641 Score = 339 bits (834), Expect = 1e-91 Identities = 175/488 (35%), Positives = 270/488 (55%), Gaps = 31/488 (6%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGG------AFLIPFTVMLVIAGL-P 78 RG W + +F NVWRFPYLCY NGGG + + F + V L P Sbjct: 34 RGQWANKAEFLLAVAGQIIGLGNVWRFPYLCYKNGGGKARDSNGYSVAFVLFSVHGSLWP 93 Query: 79 LMFMELSFGQYAALGPVAVYNKFCPLF------RGLGYGMVIVSSIVMLYYNLIIAWTIF 132 +F +G V+ FC ++ GLGY ++ +YY +I+AW +F Sbjct: 94 GLFFFCWCMTVGPIGHWKVHPSFCGVYLTSCALTGLGYASQVIILHGCVYYIVILAWALF 153 Query: 133 YMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQ--------CFNQS 184 Y+ SF + +LPW +C W+T + D N + + C S Sbjct: 154 YLLYSFQT---ELPWSHCNNTWNTGQRRA-ASVDAGFQNNSVPFFKNILCPPTETCILFS 209 Query: 185 YSVSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCL 244 + ++L K A P E++ +VL LS +++ G + +A+CL+A WVI + C+ Sbjct: 210 HQNQTGNSSLTKNATS--PVIEFWEREVLNLSDNLDKLGPVSWKLALCLVAIWVICYFCV 267 Query: 245 CKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAA 304 KGV+S+GKVVY TA FPYV+L +L RGVTLPGA GI++YL PD +LA+ QVW DA Sbjct: 268 WKGVKSTGKVVYLTATFPYVMLFVLLMRGVTLPGAGQGIIYYLKPDIGRLADPQVWMDAG 327 Query: 305 VQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHEL 364 Q+FF+ G L L SYNK++N+CY D+ ++ + N +TSF AG IFSV+GF+A E Sbjct: 328 TQVFFSYGICLGSLTALGSYNKYNNDCYKDTFLLCLLNSSTSFMAGFAIFSVLGFMAEEQ 387 Query: 365 NVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAIL 424 + + V G GLAFI YP V+ +P+ LW++ FF+M++ LGLD+QF +E + T++ Sbjct: 388 GMDISTVAQSGPGLAFIAYPRAVSMMPVPQLWAVCFFIMIIMLGLDTQFVSLEALMTSVT 447 Query: 425 DRFPNF---RQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANW-SVLIIAIGE 480 D +P+ ++ ++ + + +L GL+ T G+Y Q+ D Y+ + ++L+++I + Sbjct: 448 DLYPHLIRRGHRRKLLLLFICIACFLVGLVMVTPGGIYVFQVYDHYSCSGATLLLLSIFQ 507 Query: 481 CILIAWIY 488 + I WIY Sbjct: 508 SVAIGWIY 515 Score = 41.5 bits (93), Expect = 0.066 Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 4/66 (6%) Query: 489 GAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGH-YVYPM 547 GAE+F +I+ M G+ ++++ W+ +TPA +F+ I + P S V P Sbjct: 551 GAERFTANIRHMTGKNP---MFIFKLCWKYLTPAVCTATFLFSVINWSPLSLVRGLVAPA 607 Query: 548 WADAVG 553 WA A+G Sbjct: 608 WATALG 613 >UniRef50_UPI0000660336 Cluster: Homolog of Homo sapiens "Solute carrier family 6 (neurotransmitter transporter, GABA), member 13; n=2; Takifugu rubripes|Rep: Homolog of Homo sapiens "Solute carrier family 6 (neurotransmitter transporter, GABA), member 13 - Takifugu rubripes Length = 615 Score = 338 bits (830), Expect = 3e-91 Identities = 185/493 (37%), Positives = 266/493 (53%), Gaps = 36/493 (7%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 RG W+ + ++ NVWRFPY CY NGGGAFLIP+ ++ V+ G+PL +E S Sbjct: 11 RGQWSSKAEYVLVVAGNVVGLGNVWRFPYPCYKNGGGAFLIPYCLLAVVFGVPLFLLETS 70 Query: 86 FGQYAALGPVAVYNKFCPL-----------------FRGLGYGMVIVSSIVMLYYNLIIA 128 GQ+ G + + K CPL F G+GY ++V + Y ++ Sbjct: 71 LGQFTQEGFITCWRKVCPLAQDIQNCFEKQRTLLTGFSGIGYAQLMV-KLASFTYIMVQV 129 Query: 129 WTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLR------QCFN 182 W +FY+ SF S +LPW C W+T YS + E+ G L+ C + Sbjct: 130 WALFYLVFSFRS---ELPWATCGNAWNTG--YSEDGFLIMESTFGKMNLQWNFISDNCRD 184 Query: 183 QSYSVSHNITALAKTALRRP--PAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIV 240 + N TA +T + P A +++ ++LGLS G+EE G +R +A+CLL W+ Sbjct: 185 VWDFDAANQTA-NETRILDPTSAATQFWERRLLGLSGGVEELGSVRSELALCLLLCWLFC 243 Query: 241 FLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVW 300 F + KGV+S GKV Y TA+FP+V+LV LF R TLPGA GI YL P +LAN +VW Sbjct: 244 FFSIRKGVRSMGKVAYLTAIFPFVLLVFLFARAATLPGASDGIKQYLIPQLGRLANIEVW 303 Query: 301 GDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFL 360 +A +I + S G LI L SYN ++NNCY D+ + TSF AG ++FS++GFL Sbjct: 304 TEAGSEILSSYSLTSGILIVLGSYNPYNNNCYRDAFWICALTSGTSFVAGFIVFSILGFL 363 Query: 361 AHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVT 420 A +VS+D V + G GL FI +P+ +P+ WSI FF+ML+ L D+ F +E V Sbjct: 364 AQVYSVSIDAVAESGPGLVFIAFPQAAALMPLPQFWSICFFLMLILLAADTHFVCVEAVI 423 Query: 421 TAILDRFPNFRQ---KKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKY-AANWSVLII 476 T++ D FP + K + F++ V +L LI T G Y QL+D Y + Sbjct: 424 TSVSDLFPKLLRSPVKHEIISFLLCVSSFLVHLILATQGGNYIFQLIDYYGVTRLCDNFM 483 Query: 477 AIGECILIAWIYG 489 AI EC+ + WI+G Sbjct: 484 AICECLAVGWIFG 496 Score = 40.7 bits (91), Expect = 0.12 Identities = 23/74 (31%), Positives = 34/74 (45%), Gaps = 5/74 (6%) Query: 481 CILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASY 540 C LI+ +GA++ I M G + ++ L W+I PA + + YKP Sbjct: 520 CDLIS--HGADRLVLIIDDMTGHKPSIFFKL---CWKIFIPAFSGVCFLLYLVYYKPLHL 574 Query: 541 GHYVYPMWADAVGW 554 YVYP W +GW Sbjct: 575 DRYVYPGWVPGLGW 588 >UniRef50_UPI0000E481CA Cluster: PREDICTED: similar to solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 - Strongylocentrotus purpuratus Length = 705 Score = 332 bits (817), Expect = 1e-89 Identities = 160/455 (35%), Positives = 260/455 (57%), Gaps = 26/455 (5%) Query: 103 PLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSY 162 P++ G+G+ +++++ V YN++I+W+ +Y+ SF+ +LPW+ C EW+T C+ Sbjct: 12 PVYAGVGWAVLVIAWYVGFSYNVVISWSFYYLFASFTG---ELPWRYCDKEWNTPLCFD- 67 Query: 163 EEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAEEYFTNQVL--GLSSGIE 220 N SY ++ + PA+EYF ++L S+G+ Sbjct: 68 ----------------DTMNASYVEIDGVSVWLNYSTGNAPAKEYFDLEMLRRDRSTGLF 111 Query: 221 ETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAI 280 + + + +CL+ ++I++ + KGV++SGKVV+ TA PY VL IL RGVTLPGA Sbjct: 112 DLAGMSWQLPLCLILVFIILYFSIWKGVKTSGKVVWVTATLPYFVLTILLIRGVTLPGAG 171 Query: 281 TGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAV 340 GI +YL P+F+ LA VW DAAVQIF+++ +G I +SYNKF++N Y D++ A Sbjct: 172 DGIRYYLYPNFALLAKPTVWIDAAVQIFYSIGAGFGVHIAFASYNKFNSNVYRDAIFTAS 231 Query: 341 SNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILF 400 N TSFF+G +FS++G+L+H+ + V G GL F VYPE + +P +P WSI+F Sbjct: 232 INCFTSFFSGFAVFSILGYLSHKTGKEISEVATDGPGLVFTVYPEAIATIPGAPFWSIIF 291 Query: 401 FVMLLTLGLDSQFALMETVTTAILDRFPN-FRQKKGWVVFIVAVFGYLGGLIFTTNSGMY 459 ++ML+TLGLDS F E + T ++D+FP F++++ ++V + V + LI T G+Y Sbjct: 292 YIMLITLGLDSSFGGTEAIVTGLVDQFPKFFKKRREYLVLAIVVSFFFFTLINVTYGGIY 351 Query: 460 WLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRII 519 L ++YAA+ S+L + E +AW YG +F DIQ MIG + +W W+ + Sbjct: 352 VFHLENEYAASTSLLFVVAIEVFAVAWFYGVNRFARDIQEMIGFLPSI---VWRICWKFV 408 Query: 520 TPAALVFILVFNWIEYKPASYGHYVYPMWADAVGW 554 + + + + + + P Y Y YP W + + W Sbjct: 409 STTFVFVMFIVSMVLSTPLVYDEYTYPQWGNVLAW 443 Score = 91.1 bits (216), Expect = 8e-17 Identities = 41/144 (28%), Positives = 74/144 (51%), Gaps = 4/144 (2%) Query: 412 QFALMETVTTAILDRFPNF-RQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAAN 470 +F E + T ++D+FP F ++++ ++V + V + LI T G+Y L ++YAA+ Sbjct: 496 KFGGTEAIVTGLVDQFPKFFKKRREYLVLAIVVSFFFFTLINVTYGGIYVFHLENEYAAS 555 Query: 471 WSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVF 530 S+L + E +AW YG +F DIQ MIG + +W W+ ++ + + + Sbjct: 556 TSLLFVVAIEVFAVAWFYGVNRFARDIQEMIGFLPSI---VWRICWKFVSTTFVFVMFIV 612 Query: 531 NWIEYKPASYGHYVYPMWADAVGW 554 + + P Y Y YP W + + W Sbjct: 613 SMVLSTPLVYDEYTYPQWGNVLAW 636 >UniRef50_Q7QGR3 Cluster: Transporter; n=1; Anopheles gambiae str. PEST|Rep: Transporter - Anopheles gambiae str. PEST Length = 622 Score = 332 bits (816), Expect = 2e-89 Identities = 188/516 (36%), Positives = 278/516 (53%), Gaps = 40/516 (7%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 ER W +F NVW+FP + NGGGAF+IP+ ++L++ G P+ ++E+ Sbjct: 42 EREKWDKGVEFLMSCIALSVGLGNVWKFPSTAFRNGGGAFVIPYLIVLLVVGRPIYYLEM 101 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 GQ+++ G V VY+ P+ RG+G ++ +V++YY IA I + SF S Sbjct: 102 MMGQFSSRGSVKVYD-VSPIMRGIGIAQMVSICVVIVYYAATIATAIRFFVASFGS---P 157 Query: 145 LPWQNCKAEWSTK-HCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPP 203 LPW +C W+ +C + A FN S V KT+ Sbjct: 158 LPWASCDVSWTGGFNCVNSSNTGPTPA----------FNNSLPV--------KTS----- 194 Query: 204 AEEYFTNQVLGLSSGIEETGEIRLG---MAMCLLAAWVIVFLCLCKGVQSSGKVVYFTAL 260 AE Y+T+ V G G+ GE + + +CLL WV + + + KG++ SGKV YF AL Sbjct: 195 AELYYTHSVTG--EGLLTAGEFGVPDWKLTLCLLFIWVAMTIMMVKGIRGSGKVAYFLAL 252 Query: 261 FPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLIT 320 FPYVVL+ TL GA G+ +++TPD+ QL NA VW +A Q FF+LS +GG+I Sbjct: 253 FPYVVLISFAIYAFTLEGAGQGLKYFITPDWDQLLNADVWKEAVSQCFFSLSICFGGVIA 312 Query: 321 LSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELN-VSVDRVVDQGAGLA 379 SSYN FSNN Y D++I++ + TS +G ++FS+IG L H N +VV G+GL Sbjct: 313 FSSYNNFSNNIYRDAMIISWLDTFTSLLSGALVFSIIGHLGHLTNETDYTKVVKPGSGLT 372 Query: 380 FIVYPEVVTRLPISP-LWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVV 438 FI YP+ + + P L+++LFF MLLTLG+ S L+ +V TA+ D P + K V Sbjct: 373 FITYPDALAKFEHVPNLFALLFFFMLLTLGVGSCTGLINSVLTALHDSTPRLKSWK--TV 430 Query: 439 FIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQ 498 + V G+ GL+F T SG L D Y + L AI E W+YG K DIQ Sbjct: 431 VTIGVLGFALGLLFVTPSGSKMLDYFDYYGVQFVTLTSAIFELFAFCWLYGIRKLTRDIQ 490 Query: 499 RMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIE 534 M+ R++ +LW W+++TPA L+ +L+ ++ Sbjct: 491 FMLKRRTG---FLWRFCWKLLTPAMLIVVLIIGLVK 523 >UniRef50_Q9W4S0 Cluster: Transporter; n=14; Eumetazoa|Rep: Transporter - Drosophila melanogaster (Fruit fly) Length = 662 Score = 331 bits (814), Expect = 3e-89 Identities = 195/557 (35%), Positives = 296/557 (53%), Gaps = 69/557 (12%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 ER +W + F NVWRFPYL NGGGAFL+P+ +ML I G+P+ ++EL Sbjct: 53 ERESWDSKIMFLLATIGYAVGLGNVWRFPYLAQKNGGGAFLVPYFIMLCIQGIPIFYLEL 112 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 + GQ G + V+++ P G+G +VS IV ++Y T+ + Y Sbjct: 113 AIGQRLRKGAIGVWSQVSPYLGGIGISSAVVSYIV----------ALYYNTIIAWCLIYL 162 Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPA 204 L W+ +C + ++++ H +A + P Sbjct: 163 LHSFESPLPWA-----------DCPTR---------LYKNFTYDHEPECVASS-----PT 197 Query: 205 EEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264 + Y+ L S ++ MA+ L+ +W +V++C+ +G+ SSGK+VY TA+FPYV Sbjct: 198 QFYWYRTTLQCSESVDMPENFNYHMAIALIVSWFLVYICMVQGITSSGKIVYMTAIFPYV 257 Query: 265 VLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSY 324 VL+I FFRG+TL GA G+ TP + L + VW +A QIFF+L A+GGLI SSY Sbjct: 258 VLIIFFFRGITLKGAADGVAHLFTPRWETLLDPVVWLEAGTQIFFSLGLAFGGLIAFSSY 317 Query: 325 NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLA--------HELNVSVDR------ 370 N +NNCY D+++V+++N TS FAG+V+FSVIGF A E N V + Sbjct: 318 NPANNNCYRDAILVSLTNCGTSMFAGVVVFSVIGFKATATFDRCTEERNGLVAQNKTHNL 377 Query: 371 -VVD---------QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVT 420 V D G GLAFI++ E + + P + LW++LFF+ML TLG+DSQF +E V Sbjct: 378 PVCDLQTELANSASGTGLAFIIFTEAINQFPGAQLWAVLFFLMLFTLGIDSQFGTLEGVV 437 Query: 421 TAILDR--FPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAI 478 T+++D FPN K ++V + + F +G Y QLMD +A N+ +LIIA+ Sbjct: 438 TSLVDMKLFPNL--PKEYIVGALCFSCCTISMCFANGAGSYIFQLMDSFAGNFPLLIIAL 495 Query: 479 GECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPA 538 EC+ I++IYG +F DI+ M G + + W W+ ++P A+V IL+ ++ Y+ Sbjct: 496 FECLSISYIYGVRRFSDDIEMMTGSRPN---FYWMFCWKYLSPCAMVTILLASF--YQLL 550 Query: 539 SYGHYVYPMWADAVGWT 555 + G YP W + G T Sbjct: 551 TEGS-SYPAWIGSKGAT 566 >UniRef50_Q17EZ8 Cluster: Sodium/shloride dependent amino acid transporter; n=3; Culicidae|Rep: Sodium/shloride dependent amino acid transporter - Aedes aegypti (Yellowfever mosquito) Length = 613 Score = 330 bits (812), Expect = 5e-89 Identities = 179/573 (31%), Positives = 294/573 (51%), Gaps = 44/573 (7%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 R WT +F NVWRFPY NNGGGAF+IP+ V+L++ G PL ++E+ Sbjct: 46 RDKWTRNIEFLLSCVALSVGFGNVWRFPYTALNNGGGAFVIPYLVVLLVVGRPLYYLEMI 105 Query: 86 FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQL 145 GQ+++ G V V++ CPL RG+G G + ++ YY +++ + Y SF Y L Sbjct: 106 VGQFSSRGCVKVFD-MCPLMRGVGVGQTVTMFTIVGYYAALLSLAMRYFVDSFQ---YTL 161 Query: 146 PWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAE 205 PW C+ +W C + S + H ++ + +P A Sbjct: 162 PWSECRLDWD------------------------CVDSSKASIH----ISNSTTTKPSAV 193 Query: 206 EYFTNQVLGLSSGIEE-TGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264 YFT V G+E G + +CLL +W+++ + + KG++SSGK YF A+FPYV Sbjct: 194 FYFTEIVTNQFPGLENGIGLPNYQLVLCLLVSWILITVLVIKGIKSSGKASYFLAIFPYV 253 Query: 265 VLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSY 324 +L L R VTL GA GI +++TP + +L + +VW +A Q FF+L+ G +I SS+ Sbjct: 254 ILFGLLIRAVTLDGAFEGIKYFITPQWDKLLDTEVWYEAVSQCFFSLTIGLGAVIVYSSF 313 Query: 325 NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYP 384 N FSNN Y D++I++ + TS +G+++F V+G +A+ + +V V+ G L F+VYP Sbjct: 314 NSFSNNIYRDAMIISWLDTFTSMLSGVIVFGVVGNVAYITDKNVTDVMKNGPELTFVVYP 373 Query: 385 EVVTRLPISP-LWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAV 443 + + ++P P ++I+FF+M + LGL S ++ T+ T+I DR+P + K VV +AV Sbjct: 374 DAIAKMPTWPNFFAIMFFLMFILLGLGSNMGIVTTILTSIKDRYPGVKIWK--VVIGIAV 431 Query: 444 FGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGR 503 G+ GL++ + G Y L ++D Y + L++ + E W+YG ++ C DI+ M+ Sbjct: 432 GGFCCGLVYISPGGFYVLDVVDYYGVTFPTLVLVVLEAFTFCWLYGVDRICMDIKFMLNI 491 Query: 504 QSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGWTXXXXXXXX 563 + ++ W W T + LV I +Y+ P + GW Sbjct: 492 NTGIF---WRICWGFFTLSILVTITCMQIFKYEAKK-----VPREYNVFGWCLFGVTVLQ 543 Query: 564 XXXXXXDQICSGPDDLTIMEKARVLARPTEEWG 596 + P+ + K +PT++WG Sbjct: 544 VVVWAVCATANQPNRSGLCGKLCDALKPTKDWG 576 >UniRef50_Q9XUG5 Cluster: Transporter; n=3; Caenorhabditis|Rep: Transporter - Caenorhabditis elegans Length = 706 Score = 326 bits (801), Expect = 1e-87 Identities = 181/571 (31%), Positives = 281/571 (49%), Gaps = 28/571 (4%) Query: 10 DEEKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFT 69 D SK + +P RG W + +F N+WRFP YNNGG AFL+P+ Sbjct: 28 DSGSSKEIEESQADPCRGAWGNQIEFLLSTLGMAVGLGNIWRFPTRAYNNGGSAFLVPYV 87 Query: 70 VMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAW 129 ++ GLP +++E GQY ++ +F P+ +G+G+ V VSS+V +YY +II W Sbjct: 88 ACALLFGLPAVYLEFLLGQYHRTTAPIIFRRFAPILQGVGWMAVAVSSLVAIYYIIIIGW 147 Query: 130 TIFYMTVSFSSIFYQLPWQNCKAEWST-KHCYSYEEADECEAQNGT--------YYLRQC 180 + YM + W C W+ + C C + N T L Sbjct: 148 STVYMASIVMG--HTSKWNRCGNSWNNAESCVDSGLQPLCASFNATGNETSPVWANLSSE 205 Query: 181 FNQSYSVSHNITALAKTALRR------PPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLL 234 + + N + K L E+YF + V+ + G E I + Sbjct: 206 GRGKFYIYLNTSCYDKVDLEFNKTKMIAATEQYFFDYVVKPTDGFLEFSSINFKSFFGMN 265 Query: 235 AAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYL-TPDFSQ 293 A W+IV L L KGV GK Y PY ++++LFFRG+TL GA GI +YL PD+S+ Sbjct: 266 ACWLIVVLILWKGVGYMGKASYVIVTLPYFIIILLFFRGITLDGAEDGIYYYLGNPDWSK 325 Query: 294 LANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVI 353 + WG+A Q+ F+L +GGLI ++S++K +NNC+ D+LIV + + S G + Sbjct: 326 VFMPATWGEALKQLCFSLGIGYGGLIGMASFSKPNNNCFRDALIVIIGDTMMSLVGGAAV 385 Query: 354 FSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQF 413 FS +GFLA + SV VV+ G LAF+ +PE + R+P+ LWS LFF+ML LG+ ++ Sbjct: 386 FSTLGFLAKKKGCSVAEVVNDGFSLAFVAFPEALGRMPLPELWSFLFFLMLFFLGISTEV 445 Query: 414 ALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSV 473 A + ++I D+F N R++K V + + Y+ G++ T+ G YW + D+YAA S Sbjct: 446 AYVNVFCSSICDQFVNLRKRKWLVAVLWCLVLYVLGVVMVTDGGFYWFIMFDEYAAGVSS 505 Query: 474 LIIAIGECILIAWIYGAEKFCGDIQRMIGRQSK---LWVYLWSAM----WRIITP---AA 523 E +++A++YG D++ M G W+ S W +TP + Sbjct: 506 CCAVTAEVLIVAYVYGRRNQLADMKEMFGESKNKCTSWIGQHSPYFGFNWMFVTPVLGSI 565 Query: 524 LVFILVFNWIEYKPASYGHYVYPMWADAVGW 554 L+ + Y+ +YP+ D VGW Sbjct: 566 LIVLASIRQYPYQTDENKPNMYPLAFDIVGW 596 >UniRef50_O76188 Cluster: Potassium coupled amino acid transporter; n=2; Manduca sexta|Rep: Potassium coupled amino acid transporter - Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm) Length = 634 Score = 322 bits (791), Expect = 2e-86 Identities = 185/534 (34%), Positives = 280/534 (52%), Gaps = 38/534 (7%) Query: 24 PERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFME 83 PER W+ +F NVWRFP++ Y NGGGAFL+P+ ++L++ G P+ ++E Sbjct: 49 PERMVWSNNIEFLMSCIATSVGLGNVWRFPFIAYQNGGGAFLVPYIIVLLLVGKPVYYLE 108 Query: 84 LSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFY 143 GQ+++ V +++ P +G GY + ++ +Y+ + +FY Sbjct: 109 CVLGQFSSRNSVKIWS-ISPAMKGTGYAQAVGCGYILS----------YYVVICGLCLFY 157 Query: 144 QLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPP 203 W+ C E + C + T + V NIT +A Sbjct: 158 LAMSFQATLPWAI--CQP--EWENCVPSDPTL--------AAGVG-NITNGTSSA----- 199 Query: 204 AEEYFTNQVLGLSSGIEE-TGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFP 262 E YF VL S GIE G + +CL AW++VF + +GV+SSGK YF ALFP Sbjct: 200 -ELYFLRTVLQQSDGIEGGLGAPIWYLVLCLFIAWLMVFGVVARGVKSSGKAAYFLALFP 258 Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322 YVV++ LF V LPGA GILF++TPD+ +L VW A Q+FF+LS G +I S Sbjct: 259 YVVMITLFITTVLLPGATDGILFFVTPDWWKLLELGVWYAAITQVFFSLSVCTGAIIMFS 318 Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQ-GAGLAFI 381 SYN F N Y D+LIV + TSF +G IF ++G LA+ELN V V+ G LAFI Sbjct: 319 SYNGFKQNVYRDALIVTTLDTFTSFLSGCTIFGILGNLAYELNSDVGDVIGSGGTSLAFI 378 Query: 382 VYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIV 441 YP+ + + L+S+LFF+M+ LG+ S AL+ T+ T ++D FP R ++ + Sbjct: 379 SYPDAIAKTFQPQLFSVLFFLMMSVLGIGSSVALLSTLNTVVMDAFP--RVPTVYMSALS 436 Query: 442 AVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMI 501 G+L GL++ T G + L+L+D Y + VL AI E + WIYG E C DI+ M+ Sbjct: 437 CTCGFLLGLVYCTPGGQFILELVDHYGGTFLVLFCAISELAGVFWIYGLENLCLDIEFMM 496 Query: 502 GRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYG-HYVYPMWADAVGW 554 G+ + + W W I+TP ++ + ++ + ++ +G YVYP+ G+ Sbjct: 497 GKTTG---FYWRLCWGIVTPGMMIIVFIYALLSFENLVFGDFYVYPVAGYVAGY 547 >UniRef50_UPI000065F69C Cluster: Homolog of Homo sapiens "Solute carrier family 6 (Neurotransmitter transporter, GABA), member 13; n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens "Solute carrier family 6 (Neurotransmitter transporter, GABA), member 13 - Takifugu rubripes Length = 601 Score = 315 bits (774), Expect = 2e-84 Identities = 155/391 (39%), Positives = 231/391 (59%), Gaps = 17/391 (4%) Query: 107 GLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEAD 166 G+GYG +++ + Y +I++W + Y+ SF S QLPW C W++ + D Sbjct: 101 GIGYGGILILIYSCMTYIIILSWALLYLIFSFRS---QLPWGTCNNYWNSG------KID 151 Query: 167 ECEAQNGTYYLRQCFNQSYSV----SHNITALAKTALRRPPAEEYFTNQVLGLSSGIEET 222 NG C S S N + + A E++ +VL +S GIEE Sbjct: 152 PGCTFNGFPLSCPCLKISLSEFCISGQNTSGWSNQTNTTSAATEFWERRVLAISGGIEEI 211 Query: 223 GEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITG 282 G +R + +CL+ WVI + C+ KGV+++GKVVY TA PYV+L++L RG+TLPGA+ G Sbjct: 212 GSVRWEVLLCLMVMWVICYFCIWKGVKTTGKVVYLTATLPYVMLLVLLVRGLTLPGALDG 271 Query: 283 ILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSN 342 +L+YL P S++ + QVW +AA QIFF+ S G LI LSSYN +++NCY SL + + N Sbjct: 272 VLYYLLPQVSRMTDPQVWMEAAAQIFFSYSLGVGSLIVLSSYNNYNDNCYKSSLYLCLLN 331 Query: 343 IATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFV 402 TS AG +FSV+GF+AHE V + V + G GLAFI YP+ + +P+ LWS+ FF+ Sbjct: 332 SCTSVVAGFAVFSVLGFMAHEQGVPIADVAESGPGLAFIAYPQAIAMMPLPQLWSVCFFI 391 Query: 403 MLLTLGLDSQFALMETVTTAILDRFPNFRQKKGW---VVFIVAVFGYLGGLIFTTNSGMY 459 M++ LGLD+QF ME V T+I+D FP ++ G +F+ +F + L+ T GMY Sbjct: 392 MIIVLGLDTQFLAMEVVLTSIMDMFPKQMRRAGQRERFLFVFCLFCFFSQLVVITEGGMY 451 Query: 460 WLQLMDKYAANWS-VLIIAIGECILIAWIYG 489 QL+D YA N + +L + I E + + W++G Sbjct: 452 VFQLLDHYACNGACILFLCIFESLALGWLFG 482 Score = 50.4 bits (115), Expect = 1e-04 Identities = 19/38 (50%), Positives = 22/38 (57%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGG 62 ERG+W R ++ NVWRFPYLCY NGGG Sbjct: 3 ERGHWDKRVEYILAVAGAVVGLGNVWRFPYLCYKNGGG 40 >UniRef50_UPI0000DB790C Cluster: PREDICTED: similar to CG5549-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to CG5549-PA - Apis mellifera Length = 436 Score = 313 bits (769), Expect = 8e-84 Identities = 148/319 (46%), Positives = 208/319 (65%), Gaps = 1/319 (0%) Query: 204 AEEYFTNQVLGLSSGI-EETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFP 262 +EEYF + VLG+ E G +R + CL AW+I FLCL +GVQS GK+VYFTALFP Sbjct: 69 SEEYFNDYVLGIRGATWEHFGGVRWELLGCLTLAWIICFLCLMRGVQSIGKIVYFTALFP 128 Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322 Y +L+ L RGVTL GA+ G L+++ P +S L + VW DAA Q+F++L G LITLS Sbjct: 129 YAMLIALLIRGVTLEGALDGSLWFIMPKWSTLQSTNVWADAASQVFYSLGIGCGSLITLS 188 Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIV 382 SY+ F+NNC+ D++ V +N+ATS FAG VIFS++GFLA ++ VSV+ V+ GA LAFI Sbjct: 189 SYSNFNNNCHRDAIFVTFTNLATSIFAGFVIFSIMGFLARQMGVSVEEVIQSGAALAFIA 248 Query: 383 YPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVA 442 YPE V R+P+ +W++LFFVML LG+ SQFA ++ + TAILD P+ R+++ VVF + Sbjct: 249 YPEAVVRMPLPNVWAVLFFVMLFILGIGSQFAGVQAINTAILDLRPDLRKRESLVVFGIC 308 Query: 443 VFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIG 502 V + + + G+Y LMD A+W++L+I I E ++ W YG KF +I M Sbjct: 309 VTCWFLAIPMVFDGGIYLFTLMDWNTASWAILLIGIAEVGVVGWCYGCNKFLRNIAEMQM 368 Query: 503 RQSKLWVYLWSAMWRIITP 521 R + L W W ++ P Sbjct: 369 RFNLLLRRYWWLSWVVLAP 387 >UniRef50_UPI0000E4A4BA Cluster: PREDICTED: similar to glycine transporter type 2b; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to glycine transporter type 2b - Strongylocentrotus purpuratus Length = 458 Score = 312 bits (766), Expect = 2e-83 Identities = 166/396 (41%), Positives = 240/396 (60%), Gaps = 20/396 (5%) Query: 210 NQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVIL 269 ++V L+ GI++ G + + LAAW+IV+LC+ KGV+S+GKVVYFTA FPY+VL IL Sbjct: 3 HRVHRLTDGIDDMGTMNWDVFGAFLAAWIIVYLCIIKGVKSAGKVVYFTATFPYIVLFIL 62 Query: 270 FFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSN 329 RGVTLPGA GI+FYL PDF +LA+ + W DAA QIF++L ++G LIT +SYNKF N Sbjct: 63 LIRGVTLPGAAKGIIFYLKPDFQKLASPEPWKDAANQIFYSLGMSFGSLITFASYNKFKN 122 Query: 330 NCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTR 389 NCY D+++V+ N TS FAG VIFSV+GF+A + + V VV G GLAF VYPE ++R Sbjct: 123 NCYKDAIMVSFINCGTSIFAGFVIFSVLGFMAQDSGLEVKDVVASGPGLAFKVYPEALSR 182 Query: 390 LPISPLWSILFFVMLLTLGLDSQ-----FALMETVTTAILDRFPNFRQKKGWVVFIVAVF 444 LP+ LWSILFF MLLTLGLDSQ +L + ++ ++ P + W+ +++F Sbjct: 183 LPVPQLWSILFFFMLLTLGLDSQVQWMLLSLFQWMSISLFQWMPLSLDQ--WMP--LSLF 238 Query: 445 GYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQ 504 LI M Q W L + +G C+ + ++ G ++F GDI+ MIG Sbjct: 239 AMSEALITAIADEMSPAQ-----RKKWKWL-VTLGVCVAL-FLCGLKRFVGDIRAMIGYD 291 Query: 505 SKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGWTXXXXXXXXX 564 +++Y W W +++P A++ I+V ++ Y PA YG YV+P WA A+GW Sbjct: 292 --VFIY-WQICWAVLSPLAMLLIVVLGFVFYVPAYYGDYVFPDWAQAIGWLMAFASFLVV 348 Query: 565 XXXXXDQICSGPDDLTIMEKARVLARPTEEWGQAGS 600 + + T +++ L +PT +WG A + Sbjct: 349 PAYSIYAMIFLAEG-TFLKRVSFLMKPTWDWGPASN 383 >UniRef50_P90890 Cluster: Transporter; n=2; Caenorhabditis|Rep: Transporter - Caenorhabditis elegans Length = 768 Score = 305 bits (748), Expect = 3e-81 Identities = 170/541 (31%), Positives = 276/541 (51%), Gaps = 43/541 (7%) Query: 48 NVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRG 107 N+WRFP + Y NGG +FLI + + + +P + ME + GQYAA P AV+ + P G Sbjct: 130 NIWRFPTVAYQNGGTSFLIVYIICAFVFAVPAIHMEFALGQYAAKSPPAVFRRIMPALEG 189 Query: 108 LGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADE 167 +G+ IV +++ +YY ++I+W + Y+ +IFY C W+ +CY E Sbjct: 190 VGWMTCIVGAVIGVYYMILISWIVLYII----NIFYVNNMGRCDNPWNQNNCYDGSEQSR 245 Query: 168 CEAQNGTYYLRQCFNQSYSVSHNITALAKTALRR-----------------PPAEEYFTN 210 C N Y N S ++ + L + +R E++F+ Sbjct: 246 C---NKGLYSNMTANASSFLNTTMAPLMSSGSKRILYINGKCQDATNMSVEVGTEQFFSK 302 Query: 211 QVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILF 270 V+ S+G + I L + + WVI + L +G+++ GK+ Y T + PY ++V L Sbjct: 303 SVIRPSAGFTDFNSINLPILGAVALCWVIAAVVLIRGMKAIGKLSYVTVILPYFIIVSLL 362 Query: 271 FRGVTLPGAITGI--LFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFS 328 GV+LPGA G+ LF T DF+ L + W A QI F+LS GGL+ ++SYNK + Sbjct: 363 ICGVSLPGAKDGLYHLFGQT-DFNYLYKRETWTAALQQICFSLSIGQGGLMNIASYNKKT 421 Query: 329 NNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVS------VDRVVDQGAGLAFIV 382 N Y D I+ + S G+ +FS +GFLA+E ++ + +V +G LAFIV Sbjct: 422 YNWYRDVYIIVFLDTLMSILGGITVFSTLGFLAYERGINSTDIDAFNHIVKEGHALAFIV 481 Query: 383 YPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVA 442 Y E + +P+ LW LFF+ML LG+ ++ ++E V + + DRF R+++ V V+ Sbjct: 482 YTEAIAEMPVPYLWYALFFIMLFLLGISTEVVIVEIVCSCLADRFRYLRERRWLTVLSVS 541 Query: 443 VFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIG 502 +L GL+ TT++G YW + D+Y+ S C+ + W YG F DI M G Sbjct: 542 AVFFLLGLVMTTDAGFYWFDMFDEYSTGISATFGTAIMCMTVFWCYGTNHFREDIAVMWG 601 Query: 503 RQSKLWV--------YLWSAMWRIITP-AALVFILVFNWIEYKPASYGHYVYPMWADAVG 553 + + W+ Y W+ +W+ +TP +L+ + ++ W + P +YP DA+G Sbjct: 602 -EPESWLATCLGPAAYFWTLIWKFVTPVCSLLMMGLWIWEKKYPHKGDGKIYPPVFDALG 660 Query: 554 W 554 W Sbjct: 661 W 661 >UniRef50_Q59DZ2 Cluster: Transporter; n=4; Sophophora|Rep: Transporter - Drosophila melanogaster (Fruit fly) Length = 739 Score = 302 bits (741), Expect = 2e-80 Identities = 174/500 (34%), Positives = 258/500 (51%), Gaps = 22/500 (4%) Query: 120 MLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQ 179 + YY ++A Y SF + LPW C+AEW HC + +A N + Sbjct: 243 LTYYAALVAIIGRYFIESFRN---PLPWSTCRAEWGI-HCINSAP----DASNWSQ---- 290 Query: 180 CFNQSYSVSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEE-TGEIRLGMAMCLLAAWV 238 + N T ++ +E YF +VL IEE G + + L AW Sbjct: 291 -LESNDQRPQNYTMKSQNDRVITSSEWYFVKEVLHEKPNIEEGIGLPNWELVIGLFIAWS 349 Query: 239 IVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQ 298 VF + +GV+SSGK YF ALFPYV++ +L R VTLPG+I GI +++ P + ++ + + Sbjct: 350 CVFFIIRRGVKSSGKASYFLALFPYVIMGVLLVRAVTLPGSIDGIYYFIKPQWGKILDPK 409 Query: 299 VWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIG 358 VW A Q F++LS +G +I SS+NKF +N + D+ IV + TS AG IF ++G Sbjct: 410 VWYAAVTQCFYSLSVCFGNIIMYSSFNKFGHNVHRDAAIVTGLDTMTSLLAGFTIFGILG 469 Query: 359 FLAHELNV-SVDRVVDQGAGLAFIVYPEVVTRLPISP-LWSILFFVMLLTLGLDSQFALM 416 LAHE+ + VV GAGLAFI YP+ + + P ++S+LFF+ML LG+ S A+ Sbjct: 470 HLAHEIGTDDIGSVVKGGAGLAFISYPDAIAKFKNLPQIFSVLFFLMLFVLGIGSNIAMT 529 Query: 417 ETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLII 476 TAI DRFPNF Q + ++AV + GL++ T G Y L L+D + A+ L++ Sbjct: 530 SCSVTAIRDRFPNFGQWQ--CSLLIAVVSFFIGLMYITPGGQYMLTLVDFFGASMIALVL 587 Query: 477 AIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYK 536 I E I WIYG ++ C DI+ M+GR+ L+ W W IITP + IL++ + Y+ Sbjct: 588 GIAELYTIGWIYGTDRLCKDIEFMLGRKVGLY---WRLCWSIITPLIMTVILIYFYATYQ 644 Query: 537 PASYGHYVYPMWADAVGWTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWG 596 P +Y + VYP W+ ++GW I P T+ K R P + WG Sbjct: 645 PLTYNNIVYPNWSYSIGWLITAFGILQLPIWMIVAIVRDPGQ-TLGAKIRGAFTPKKNWG 703 Query: 597 QAGSTATCLSTLRVETELSP 616 + +E EL+P Sbjct: 704 PSDPLLREQYHKEIENELTP 723 Score = 80.6 bits (190), Expect = 1e-13 Identities = 54/176 (30%), Positives = 82/176 (46%), Gaps = 38/176 (21%) Query: 10 DEEKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFT 69 D+E +K P ER W +F NVWRFP+ +NGGGAFLIP+ Sbjct: 40 DQEAAKVP------EERATWGKGVEFLMSCIAMSVGLGNVWRFPFTALDNGGGAFLIPYL 93 Query: 70 VMLVIAGLPLMFMELSFGQYAALGPVAVYN-------------------------KFCPL 104 ++L + G P+ ++E+ GQ+++ G V V++ + CP Sbjct: 94 IVLFLIGKPIYYLEMVIGQFSSRGSVKVFDLCPAMKEYDNSELQNLHRHSVHQLARSCPK 153 Query: 105 F--RGLGYGM--VIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWST 156 + +G G+ VI S+V YY I+ T+ Y+ SF S LPW C+ EW + Sbjct: 154 YATTSIGVGIGQVISISMVTTYYVAIMGITLRYLYESFRS---PLPWSECRPEWES 206 >UniRef50_UPI0000E49DFE Cluster: PREDICTED: similar to taurine transporter, partial; n=9; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to taurine transporter, partial - Strongylocentrotus purpuratus Length = 818 Score = 291 bits (714), Expect = 4e-77 Identities = 172/496 (34%), Positives = 266/496 (53%), Gaps = 31/496 (6%) Query: 64 FLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYY 123 FL+P+ + + PL+F+E++ GQY + GP+ + K CP+F+G+G +V+ +YY Sbjct: 123 FLVPYFLCSLFLATPLLFLEMALGQYTSSGPIRAW-KICPIFQGIGVATTVVAWWRNIYY 181 Query: 124 NLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQ 183 N+I+AWT++Y+ S I +LPW C EW+T C +Y +E NGTY +N Sbjct: 182 NVILAWTLYYLYSS--CIGGELPWARCNNEWNTASCLNY--GNEWVCVNGTYIPIDKWNA 237 Query: 184 --------SYSVSHNITALAKT------ALRRPPAEEYFTNQVLGLSSGIEETGEIRLGM 229 S+S + L + L PA+E++ +VLG +G G + + Sbjct: 238 PPEESPAPSWSSWNEAVPLDDSDQCGNYPLTTNPAQEFWRIKVLG-QTGTGGRGIVG-HL 295 Query: 230 AMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTP 289 A+ L AW +V+ L KGV+ SGKV YFT F ++V +L RG+TLPGA G++FYL P Sbjct: 296 ALTLFLAWTLVYFGLRKGVKWSGKVAYFTVPFIHLVFAVLMIRGITLPGAYDGLIFYLKP 355 Query: 290 DFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFA 349 S+L NAQ W A ++F++ S G L S+NKF N Y DS+I A N+ TS ++ Sbjct: 356 IPSRL-NAQAWIAAGTEVFYSFSIGLGAFTALGSFNKFHYNFYRDSIIAAYLNVWTSIYS 414 Query: 350 GLVIFSVIGFLAHELNVSVDRVVDQGAGLA--FIVYPEVVTRLPISPLWSILFFVMLLTL 407 G+++F+ +G A+ +S ++ G+G F V+P LP+ +WSI FF+ +LT+ Sbjct: 415 GIIVFTFLGVEAYSEGISPGVIIADGSGSGRFFKVFPRSFAALPVPRVWSIFFFLAVLTI 474 Query: 408 GLDSQFALMETVTTAILDRFPNFRQKKGW-VVFIVAV--FGYLGGLIFTTNSGMYWLQLM 464 GL+SQ ++ T++LD FP + + + VF++ V +L GL T G Y L L Sbjct: 475 GLNSQLVTVKAFITSVLDLFPTWLRIGYYKEVFVLGVCFLNFLIGLSMVTQDGEYVLWLF 534 Query: 465 DKYAANWSVLI-IAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAA 523 D Y + LI I E I I W+YG KF +I M+ Q W + W P Sbjct: 535 DAYGSGIFPLIWICFFESIAIGWVYGVRKFSFNIAEMLRWQQIQWYII---CWIATVPVI 591 Query: 524 LVFILVFNWIEYKPAS 539 +F+ + N + + S Sbjct: 592 ALFVWINNIVSWSTLS 607 Score = 80.2 bits (189), Expect = 2e-13 Identities = 36/92 (39%), Positives = 56/92 (60%), Gaps = 5/92 (5%) Query: 84 LSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFY 143 ++ GQY + GP+ + K CP+F+G+G +V+ +YYN+I+AWT++Y+ S I Sbjct: 1 MALGQYTSSGPIRAW-KICPIFQGIGVATTVVAWWRNIYYNVILAWTLYYL--YSSCIGG 57 Query: 144 QLPWQNCKAEWSTKHCYSYEEADECEAQNGTY 175 +LPW C EW+T C +Y +E NGTY Sbjct: 58 ELPWARCNNEWNTASCLNY--GNEWVCVNGTY 87 >UniRef50_Q5XIV7 Cluster: Transporter; n=2; Eutheria|Rep: Transporter - Rattus norvegicus (Rat) Length = 509 Score = 287 bits (704), Expect = 6e-76 Identities = 171/485 (35%), Positives = 258/485 (53%), Gaps = 54/485 (11%) Query: 21 EIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLM 80 +IE ER W + + N+WRFPYLC+ +GGGAFLIP+ + LV G+PL Sbjct: 12 DIEDERPKWDNKLQYLLSCIGFAVGLGNIWRFPYLCHTHGGGAFLIPYFIALVFEGIPLF 71 Query: 81 FMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSS 140 ++EL+ GQ G + V+ P G+G G VS +V LYYN I+ W +++ SF Sbjct: 72 YIELAIGQRLRRGSIGVWKTISPYLGGVGLGCFSVSFLVSLYYNTILLWVLWFFLNSFQ- 130 Query: 141 IFYQLPWQNCKAEWSTKHCYSYEEADECEAQ-NGTYYLRQCFNQSYSVSHNITALAKTAL 199 + LP WST C N T ++++C S +VS+ Sbjct: 131 --HPLP-------WST-----------CPLDLNRTGFVQEC-QSSGTVSY---------- 159 Query: 200 RRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTA 259 ++ Q L ++S I TG I+ + +CL+A W V+LC+ +G++S+GKV+YFTA Sbjct: 160 -------FWYRQTLNITSDISNTGTIQWKLFLCLVACWTTVYLCVIRGIESTGKVIYFTA 212 Query: 260 LFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLI 319 LFPY+VL I RG+TLPGA G+ + TP+ L N +VW DAA QIFF+LS A+GG I Sbjct: 213 LFPYLVLTIFLIRGLTLPGATEGLTYLFTPNMKILQNPRVWLDAATQIFFSLSLAFGGHI 272 Query: 320 TLSSYNKFSN-NCYIDSLIVAVSNIATSFFAGLVIF---------SVIGFLAHELNVSVD 369 +SYN+ N I+ +I+ + ++++ + + L +D Sbjct: 273 AFASYNQPRNILSLINEFDFPELSISRDEYPSVLMYLNATQPERVARLPLKTCHLEDFLD 332 Query: 370 RVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDR--F 427 + G GLAFIV+ E V +P + +WS+LFF ML TLGL S F ME V T + D Sbjct: 333 KSA-SGPGLAFIVFTEAVLHMPGASVWSVLFFGMLFTLGLSSMFGNMEGVITPLFDMGIL 391 Query: 428 PNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWI 487 P K+ + +V +L + FT SG YWL++ D +AA+ +++I A E + + + Sbjct: 392 PKGVPKE-TMTGVVCFICFLSAICFTLQSGSYWLEIFDSFAASLNLIIFAFMEVVGVIHV 450 Query: 488 YGAEK 492 YG ++ Sbjct: 451 YGIKR 455 >UniRef50_Q4SBR5 Cluster: Transporter; n=1; Tetraodon nigroviridis|Rep: Transporter - Tetraodon nigroviridis (Green puffer) Length = 545 Score = 276 bits (676), Expect = 2e-72 Identities = 152/494 (30%), Positives = 256/494 (51%), Gaps = 25/494 (5%) Query: 18 LSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGL 77 +SEE R W + +F +W FP+ C + GG FLIP+ V L G+ Sbjct: 19 VSEEAARPRAKWANKMEFFLCASTQTTSYNFMWIFPFFCIHYGGAVFLIPYCVSLFFCGM 78 Query: 78 PLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLII-AWTIFYMTV 136 PL+ + L+ GQY + V + K CP+F+G+G +++ + + L++ W++ Y+ Sbjct: 79 PLLLLGLAMGQYTSESGVTAWKKICPMFQGIGIASMVILIYMSISSELLMPVWSLLYL-- 136 Query: 137 SFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAK 196 ++S+ LPW C W+T+ C S G + N + ++I+ A+ Sbjct: 137 -YNSVKSPLPWTTCDNAWNTEMCVSRTNPASSNTSVGQRD-DEWMNLTTGF-YDISETAE 193 Query: 197 TALRR---PPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGK 253 R P + N G + + CL WV+ + C KG++ +GK Sbjct: 194 MEFWRSINPTQTDNAWNDKFG--------SPLHWSLIPCLFIVWVLCYFCTWKGIKYTGK 245 Query: 254 VVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWG-DAAVQIFFALS 312 ++Y A FPY++L+ILF R VTLPGA G+ + PDF ++ +W + + FA S Sbjct: 246 IMYMVA-FPYLLLIILFIRSVTLPGAGEGLKYLFIPDFHVFSSPYIWMFSVSYSLHFATS 304 Query: 313 PAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVV 372 G TL SYNK++N+CY D+LI+ ++AT F + FS IGF+AH S + V+ Sbjct: 305 T--GVRTTLGSYNKYNNDCYRDTLILCALHVATIIFFNCIAFSFIGFVAHIEEASFNDVM 362 Query: 373 DQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNF-R 431 G + F++ P+ ++ + S W++L+F M + L Q L+E++ T + D P + R Sbjct: 363 RTGTDMLFVLVPKALSLVAGSSFWTVLYFFMTILFTLSHQIVLVESLATNVNDLLPRYLR 422 Query: 432 QKKGWVVFIVAVFG--YLGGLIFTTNSGMYWLQLMDKYAANWSV-LIIAIGECILIAWIY 488 ++ + ++AV G L L+ T G+++LQL+D YA ++++ I E I++AW+Y Sbjct: 423 KRHARELVVLAVCGLCLLVWLLIITKGGLFFLQLVDYYALSFTITYFIVCFETIVVAWVY 482 Query: 489 GAEKFCGDIQRMIG 502 GA++F +I MIG Sbjct: 483 GADRFYDNIADMIG 496 >UniRef50_A7RFF4 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 523 Score = 275 bits (674), Expect = 3e-72 Identities = 147/349 (42%), Positives = 209/349 (59%), Gaps = 25/349 (7%) Query: 201 RPPAEEYFTNQVLGLSSGIEETGE-IRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTA 259 R P+ YF + L +S+ IE+TG I + +A CL+ AW++ +LC+ KG++SSGKVVYFTA Sbjct: 138 RDPSAYYFYHHALEVSTSIEDTGVGINVKLAGCLVFAWILTYLCVVKGIKSSGKVVYFTA 197 Query: 260 LFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLI 319 FPY++L+ILFFRGVTL GA GI TPD+ L +A +W DAA Q+FF LS +G LI Sbjct: 198 TFPYIILIILFFRGVTLEGAGNGIKTLFTPDWGLLLDANIWKDAATQMFFTLSLGFGALI 257 Query: 320 TLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRV-------- 371 +SY N D V + N TS FAG+V+FS++G+ + + V V Sbjct: 258 AFASYMPMHNQVMKDGYTVVLVNCGTSLFAGIVVFSILGYREAKTGIPVTEVWTIRRVSG 317 Query: 372 ---------VDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTA 422 V G GLAFI + + + + +SPLW+ILFF+ML+ LG+DS+F +E Sbjct: 318 FAYGGRGLRVGSGPGLAFITFSDAMLLMDVSPLWAILFFMMLILLGIDSEFGTLEAAIGP 377 Query: 423 I--LDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGE 480 I L+ FP R K V VAV L GL T+ +G Y Q+ D Y+ +L+IA+ + Sbjct: 378 IMELNLFPKVR--KELVTLGVAVILLLLGLCMTSGAGYYIFQMFDDYSVTIPLLVIALFQ 435 Query: 481 CILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILV 529 CI +AW+YG ++F DIQ M G++ WV W W+ I+P AL+ +L+ Sbjct: 436 CIGVAWVYGNDRFADDIQFMTGKRP--WVG-WMICWKYISPIALLVVLI 481 Score = 111 bits (266), Expect = 7e-23 Identities = 50/124 (40%), Positives = 71/124 (57%), Gaps = 3/124 (2%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 ER W + +F NVWRFPYLC NGGGAFL+P+ + ++I GLPL F+EL Sbjct: 2 ERETWGHKAEFILATIGLAVGLGNVWRFPYLCQKNGGGAFLVPYIIFMLIEGLPLFFLEL 61 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 S GQ + + P G+G ++VS ++ LYY +IIAW ++ +SF+S Sbjct: 62 SIGQRMRKSAINCWRDIHPCLFGIGVACLMVSLMLCLYYIVIIAWCCYFFFISFTS---D 118 Query: 145 LPWQ 148 LPW+ Sbjct: 119 LPWK 122 >UniRef50_Q4RX19 Cluster: Transporter; n=1; Tetraodon nigroviridis|Rep: Transporter - Tetraodon nigroviridis (Green puffer) Length = 565 Score = 273 bits (669), Expect = 1e-71 Identities = 134/335 (40%), Positives = 190/335 (56%), Gaps = 13/335 (3%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 ERG W + +F NVWRFPYLCY NGGGAF +P+ + V G+P+ F+E Sbjct: 7 ERGQWNSKIEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFVPYVIFFVCCGIPVFFLET 66 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 + GQ+ + G + + K CPLF G+GY ++ + + +YY +I+AW IFY+ F++ + Sbjct: 67 ALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIVILAWAIFYLFNCFTT---E 123 Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPA 204 LPW C W+T + + C + C + + NIT T+ P Sbjct: 124 LPWAGCGHYWNTGSSNAPFVSHLC------FSAENCIDYYGENATNITNPNATS----PV 173 Query: 205 EEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264 E++ +VL +S GIE G +R +AMCL AW I + C+ KG +S+GKVVY TA FPYV Sbjct: 174 IEFWERRVLKISDGIEHMGGVRWELAMCLALAWFICYFCIWKGPKSTGKVVYVTATFPYV 233 Query: 265 VLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSY 324 +L++L RGVTLPGA GI FYL PD S+L++ QVW DA QIFF+ + G L L SY Sbjct: 234 MLLVLLIRGVTLPGAYDGIKFYLYPDISRLSDPQVWVDAGTQIFFSYAICLGCLTALGSY 293 Query: 325 NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGF 359 N + NNCY + + + I +S V S + F Sbjct: 294 NAYDNNCYRYGGVFSTAYIYSSELCACVTVSPMVF 328 Score = 121 bits (292), Expect = 5e-26 Identities = 57/124 (45%), Positives = 87/124 (70%), Gaps = 3/124 (2%) Query: 334 DSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPIS 393 D +++ N TSF AG IFSV+GF+A+E NV ++ V + G GLAFI YP+ VT +P++ Sbjct: 337 DCIMLCCLNSGTSFLAGFAIFSVLGFMAYEQNVPIEAVAESGPGLAFIAYPKAVTMMPLA 396 Query: 394 PLWSILFFVMLLTLGLDSQFALMETVTTAILDRFP-NFRQ--KKGWVVFIVAVFGYLGGL 450 PLW+ LFF+ML+ LGLDSQF +E++ TA++D +P FR+ ++ ++ ++V +L GL Sbjct: 397 PLWACLFFMMLIFLGLDSQFVCVESLVTAVVDLYPETFRRGYRRELLILGMSVVSFLIGL 456 Query: 451 IFTT 454 I T Sbjct: 457 IMCT 460 >UniRef50_O45813 Cluster: Transporter; n=2; Caenorhabditis|Rep: Transporter - Caenorhabditis elegans Length = 1022 Score = 269 bits (659), Expect = 2e-70 Identities = 151/479 (31%), Positives = 254/479 (53%), Gaps = 32/479 (6%) Query: 29 WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQ 88 W + DF + RFP Y +GGG F IP+ L+ GLPL+F+ LS GQ Sbjct: 160 WRTQKDFFLSCLGFMVGVGHTMRFPAKVYQHGGGVFFIPYLFSLIFFGLPLVFLHLSLGQ 219 Query: 89 YAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFY--QLP 146 Y + + P+ G+G+ +V+++ V +YYN+I+AW I Y S + +LP Sbjct: 220 YTGQAANTAFQRLMPIGSGVGWALVVIAIPVAVYYNIIVAWAIHYFFQSAKGLLLGDELP 279 Query: 147 WQNCKAEWSTKH-CYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAE 205 W+ C+ EW + C C N L CFN + S ITA E Sbjct: 280 WETCRDEWQLDNRC--------CNLHN----LHSCFNSTNS----ITA----------PE 313 Query: 206 EYFTNQVLGLSS-GIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264 +F ++VL LS+ G G ++ + + L AAW++VF + KG+ S + + TA PY+ Sbjct: 314 AFFHSEVLSLSTFGDFALGPLQSHLVLSLAAAWLLVFFGVFKGLGSIAQTMNVTATVPYL 373 Query: 265 VLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSY 324 +L IL RG++LPGA G+ F T D ++L Q+W AA Q+F+ L G LI+++++ Sbjct: 374 LLSILLLRGISLPGANKGLTFLFTVDSTKLWKWQIWKSAAEQVFYELGIDAGPLISMAAF 433 Query: 325 NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQG-AGLAFIVY 383 +++ NN Y DS+++ + + TS +G+VIFS +GF+A E N +V+ V+ L+F VY Sbjct: 434 SRYRNNIYRDSVLLVIMDALTSCLSGMVIFSFVGFIASESNSNVNDVLKHDPLYLSFTVY 493 Query: 384 PEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFP-NFRQKKGWVVFIVA 442 P V + + LW+ LFF ML+ +D++FA +E + +A ++ F + + ++ + Sbjct: 494 PGVTSFMYWGGLWATLFFGMLVLAAIDAEFAWLEMIASAFMNHFSMKNKAVENRLLAFLC 553 Query: 443 VFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMI 501 + G+ GL G++ ++ ANW+ +A+ ++ ++YG + + DI M+ Sbjct: 554 LAGFFLGLPLCAQGGIFVFHAIENLNANWNSFSLALLSVAIVCYVYGIDNYLTDISAML 612 >UniRef50_Q4SR96 Cluster: Transporter; n=4; cellular organisms|Rep: Transporter - Tetraodon nigroviridis (Green puffer) Length = 1013 Score = 258 bits (632), Expect = 3e-67 Identities = 135/314 (42%), Positives = 193/314 (61%), Gaps = 28/314 (8%) Query: 244 LCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYL--TPDFSQLANAQVWG 301 L K V++ G VVYFTA FPYVV++IL RG TL GA GI FY+ + +++ + QVW Sbjct: 289 LLKRVRNGGAVVYFTATFPYVVILILLIRGATLEGARDGIEFYIGSQSNLTKVLDVQVWK 348 Query: 302 DAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLA 361 DAA Q F++LS WGG++TLSSYN F NN + D+ +V ++N TS AG IFS++G +A Sbjct: 349 DAATQTFYSLSIGWGGVMTLSSYNNFHNNMFKDTFVVTLTNAGTSVVAGFAIFSILGHMA 408 Query: 362 HELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQF-ALMETVT 420 H + V VV +G GLAFI YP+ +++LP+SPLWSILFF MLLT+GLDSQF ++E +T Sbjct: 409 HVYQMPVGEVVKEGFGLAFIAYPDALSKLPVSPLWSILFFFMLLTVGLDSQFTGIVEVLT 468 Query: 421 TAILDRFPNF-RQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIG 479 T + D FP F K+ WV + YL GL + +G+YW+ L+D++ A+W +L + + Sbjct: 469 TCLTDAFPKFLSNKRIWVTVPTCLVLYLLGLPCVSRAGIYWVTLIDQFVASWVLLFLTLL 528 Query: 480 ECILIAWIY------------------------GAEKFCGDIQRMIGRQSKLWVYLWSAM 515 E I + +IY G +F DI+ M+G++S L+ W A Sbjct: 529 EIIGVCYIYGKHSCLEAMAAAAAAVTFSPHASAGGNRFIEDIEMMLGKKSCLFWLWWRAC 588 Query: 516 WRIITPAALVFILV 529 W I+P +V + V Sbjct: 589 WFCISPCIIVRLKV 602 Score = 251 bits (615), Expect = 4e-65 Identities = 138/313 (44%), Positives = 197/313 (62%), Gaps = 29/313 (9%) Query: 107 GLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEAD 166 G+G+ MV+VS +V +YYN+IIA++++Y+ SF S LPW C C S A Sbjct: 685 GVGFSMVMVSMLVAVYYNVIIAYSLYYLFASFQS---PLPWAACSG------CSSASTA- 734 Query: 167 ECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIR 226 S +VS + A + P+E Y+ + VL SSG+++TG + Sbjct: 735 -----------------SCNVSGVLVANHTCPPGQSPSEHYWDHVVLQRSSGLDDTGPVV 777 Query: 227 LGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFY 286 +A+CL + V+V L +G++SSGKVVYFTA FPYVV++IL RGVTL GA G+ F+ Sbjct: 778 WHLAVCLGLSSVLVAGILSRGIKSSGKVVYFTATFPYVVILILLVRGVTLEGAGEGLKFF 837 Query: 287 L--TPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIA 344 + ++S+LA +VW DAA Q FF LS GGL TLSSY++F N ++DS++V + Sbjct: 838 IGSKSNWSKLAEVKVWNDAAAQTFFTLSIGMGGLFTLSSYSEFHTNIFLDSVVVVFVSYG 897 Query: 345 TSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVML 404 TS AG+ IFS++G +AH +++VV +G GLAFIVYPE +T+LPIS LW +LFFVML Sbjct: 898 TSVLAGVAIFSILGHMAHVYKRPIEKVVKEGFGLAFIVYPEALTQLPISALWCVLFFVML 957 Query: 405 LTLGLDSQFALME 417 + + +DSQF L+E Sbjct: 958 IVISVDSQFTLIE 970 Score = 159 bits (387), Expect = 2e-37 Identities = 91/245 (37%), Positives = 138/245 (56%), Gaps = 21/245 (8%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 ERG WT + ++ N+WRFPYL Y NGGGAFLIP+ VMLV+ G+PL F+E Sbjct: 1 ERGTWTSKKEYILSTIGYAVGLGNIWRFPYLAYKNGGGAFLIPYFVMLVVTGIPLFFLES 60 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 +FGQ+ + GP+ V+ + P+ +G+G GMV+V+ IV +YYN+I+A++++YM SF S Sbjct: 61 AFGQFCSQGPINVW-RAVPILQGVGVGMVMVTLIVSIYYNVILAYSLYYMFASFQS---P 116 Query: 145 LPWQNCKAEWSTKHCYSYEE------------ADECEAQNGTYY--LRQCFNQSYSVSHN 190 LPW W+ +C S DE E + + L N S ++ N Sbjct: 117 LPWSGF-FSWAEGNCSSTPAGALMVVTVALPLCDEGEKPSRCLFFALSASCNGSGVLAAN 175 Query: 191 ITALAKT--ALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGV 248 T T + + P+E Y+ L SSG++ETG + +A+CLL + ++V L KG+ Sbjct: 176 GTQENSTCPSSVQSPSELYWDCVALQRSSGLDETGPVVWHLALCLLLSSILVCAALIKGI 235 Query: 249 QSSGK 253 ++ GK Sbjct: 236 KAEGK 240 Score = 44.8 bits (101), Expect = 0.007 Identities = 17/52 (32%), Positives = 28/52 (53%) Query: 24 PERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIA 75 PER +W+ R ++ N+W+FP+L Y+NGGG V +++A Sbjct: 647 PERLHWSSRAEYMLSMVGFAIGLGNIWKFPWLAYSNGGGVGFSMVMVSMLVA 698 >UniRef50_A6LMJ8 Cluster: Sodium:neurotransmitter symporter precursor; n=1; Thermosipho melanesiensis BI429|Rep: Sodium:neurotransmitter symporter precursor - Thermosipho melanesiensis BI429 Length = 498 Score = 254 bits (621), Expect = 7e-66 Identities = 135/354 (38%), Positives = 212/354 (59%), Gaps = 14/354 (3%) Query: 206 EYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVV 265 ++F N+ L +S+G E G IR + + L W+ ++ L KG S GK V +T P ++ Sbjct: 125 KFFFNEFLQVSNGPSELGSIRWPIVIGLALTWLWIYFILRKGTTSVGKTVAWTVPLPVIL 184 Query: 266 LVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYN 325 L+IL RG+TL GA G+ F P+F++LA +VW +A QIFF LS A+G +I SYN Sbjct: 185 LIILGIRGITLEGAAQGLNFLFQPNFAKLAEPRVWANAFGQIFFTLSLAFGIMIAYGSYN 244 Query: 326 KFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPE 385 K + +++I A+ N ATSF AG+ +FSV+G++A ++N +D VV G GLAF+VYP+ Sbjct: 245 KKEEDIANNAIITALGNSATSFLAGIAVFSVLGYMALQINSPIDEVVSGGIGLAFVVYPQ 304 Query: 386 VVTRLP----ISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIV 441 ++ P + + + FFVMLLTLG+DS F+L+E V A D+F F ++ + F Sbjct: 305 AISLFPGGVIVQSIIGLAFFVMLLTLGIDSAFSLVEAVEAAASDKF-KFNKRSFLIGF-- 361 Query: 442 AVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMI 501 ++FG+L GL+++T G+YWL ++D + + +++LI+ I E I+I W+ AEK ++ I Sbjct: 362 SIFGFLVGLLYSTQGGLYWLDIIDHFLSIYALLIVGILESIIIGWVLDAEK----LRNYI 417 Query: 502 GRQSKLWVYLW-SAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGW 554 + S++ + W R I P +L+ IL + YG YP WA G+ Sbjct: 418 NKVSEVKIGKWFDISLRYIIPGSLIIILGLTLYDEIKNPYGG--YPTWALLTGF 469 Score = 86.2 bits (204), Expect = 2e-15 Identities = 39/113 (34%), Positives = 58/113 (51%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 R W R+ F N WRFPY+ Y+NGGGAF +P+ + L +AG+PL+ E + Sbjct: 3 RQKWGSRWAFVLAAIGSAAGLGNAWRFPYMAYSNGGGAFYVPYFIALFLAGIPLLMAEFA 62 Query: 86 FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSF 138 GQ G K +G+ VI +++ YYN+I+A+ Y+ SF Sbjct: 63 IGQGFQSGAPRSLAKIKKGAEFIGWWAVITGALITFYYNVIMAYIFNYLYYSF 115 >UniRef50_A1ZBC7 Cluster: Transporter; n=5; Diptera|Rep: Transporter - Drosophila melanogaster (Fruit fly) Length = 561 Score = 250 bits (612), Expect = 9e-65 Identities = 124/328 (37%), Positives = 189/328 (57%), Gaps = 7/328 (2%) Query: 229 MAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLT 288 + CL AW+++ L +G++SSGK YF +FPYVVL+IL R VTLPGAI GI+++ Sbjct: 184 LVACLAIAWLVIGGVLIRGIKSSGKAAYFLGVFPYVVLLILLLRAVTLPGAIDGIIYFFK 243 Query: 289 PDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFF 348 P + +L N VW A Q+FF+L+ +G LIT +SYN F+ N Y D +I+ + +S Sbjct: 244 PQWRELLNPLVWYAAVTQVFFSLAICFGTLITYASYNNFNRNVYNDIVIITTMDSCSSII 303 Query: 349 AGLVIFSVIGFLAHEL-NVSVDRVVDQGAGLAFIVYPEVVTRLPISP-LWSILFFVMLLT 406 AG + F ++G LA E N + VV GAGLAFI YPE + + P ++++LFF+ML Sbjct: 304 AGCITFGILGNLARETGNPDIGSVVKGGAGLAFISYPEAIAKFEYVPQMFAVLFFLMLFV 363 Query: 407 LGLDSQFALMETVTTAILDRFPNFRQKKGW-VVFIVAVFGYLGGLIFTTNSGMYWLQLMD 465 LG+ S + + I D+F R W + + V G+ +++ T G + L L+D Sbjct: 364 LGIGSTVGMGSCILRVIRDQF-GLRSPPIWKLASGLTVLGFSVSIVYMTPGGQFILNLVD 422 Query: 466 KYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALV 525 Y +++ LI+AIGE + +AWIYG +FC DI+ M+G ++ + W WR ITP + Sbjct: 423 FYGVSFTALILAIGELVAVAWIYGVNRFCEDIKFMMGIETG---WYWRLCWRFITPGLMT 479 Query: 526 FILVFNWIEYKPASYGHYVYPMWADAVG 553 +L++ ++ Y YP A G Sbjct: 480 AVLIYMLLDMSALEYKGVGYPTLAHVFG 507 Score = 104 bits (249), Expect = 8e-21 Identities = 47/145 (32%), Positives = 77/145 (53%), Gaps = 8/145 (5%) Query: 12 EKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVM 71 +KS+ P + E W +F N+WRFPY+ + NGGG F+IP+ + Sbjct: 8 KKSEKPAEKPAE----QWGNGLEFLFSCISLSVGLGNIWRFPYIAFQNGGGTFVIPYLIA 63 Query: 72 LVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTI 131 L++ G P+ ++E+S GQ+ G V ++ PL +G+ G V+ ++ + YY+ I+A T+ Sbjct: 64 LLVIGRPVYYLEISLGQFTGRGVVKAFD-MAPLLKGVALGQVLATAASITYYSSIMALTL 122 Query: 132 FYMTVSFSSIFYQLPWQNCKAEWST 156 + SF S +LPW C W T Sbjct: 123 RFWLASFGS---ELPWSRCWESWGT 144 >UniRef50_UPI000066095C Cluster: Homolog of Brachydanio rerio "Glycine transporter 2.; n=1; Takifugu rubripes|Rep: Homolog of Brachydanio rerio "Glycine transporter 2. - Takifugu rubripes Length = 416 Score = 246 bits (603), Expect = 1e-63 Identities = 122/321 (38%), Positives = 194/321 (60%), Gaps = 14/321 (4%) Query: 208 FTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLV 267 F ++L +SG+EE G ++ + +CLL AW +V+LC+ KGV+S+GKVVYFT FPY++L+ Sbjct: 5 FRYRMLQQTSGLEEMGTVQWELCLCLLLAWTLVYLCIFKGVKSTGKVVYFTVTFPYIILI 64 Query: 268 ILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKF 327 L LPGA+ GI F++ P + +L +VW +AA QIF ++ ++G L+ +SSYN Sbjct: 65 ALLIHYAQLPGALEGIKFFILPQWEKLRLVEVWVNAAAQIFNSIGLSYGSLLAMSSYNS- 123 Query: 328 SNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVV 387 +D+L +++ N TS AG VIFS G++++ + V + G GL FIVYP+ + Sbjct: 124 -----LDTLTISIVNSLTSILAGFVIFSAFGYMSYLQGIPVTDLPVDGPGLVFIVYPQAL 178 Query: 388 TRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFP----NFRQKKGWVVFIVAV 443 +P + LWS+LFF+MLL LGLDS+FA +E + T++LD F F ++K V +V Sbjct: 179 ANIP-AQLWSVLFFLMLLCLGLDSEFAGVEVIVTSLLDGFHYDLIRFLRRKEVFVLVVCG 237 Query: 444 FGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGR 503 +L G+ G+Y QL+D Y A S+L ++ E I + WIYG + ++ M G+ Sbjct: 238 AQFLFGIPCVLQGGIYIFQLLDYYTAIVSLLFVSFFEVIAVCWIYGVSRLSNILEEMTGK 297 Query: 504 QSKLWVYLWSAMWRIITPAAL 524 + ++ + W +I P + Sbjct: 298 RPNIF---FRTCWLVIAPVLI 315 Score = 46.0 bits (104), Expect = 0.003 Identities = 16/34 (47%), Positives = 24/34 (70%) Query: 521 PAALVFILVFNWIEYKPASYGHYVYPMWADAVGW 554 P + + IL+F+ I++KPA Y YV+P WA +GW Sbjct: 348 PGSALVILIFSIIQFKPARYEDYVFPPWAQGIGW 381 >UniRef50_O18288 Cluster: Transporter; n=1; Caenorhabditis elegans|Rep: Transporter - Caenorhabditis elegans Length = 635 Score = 238 bits (582), Expect = 4e-61 Identities = 131/367 (35%), Positives = 200/367 (54%), Gaps = 22/367 (5%) Query: 210 NQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVIL 269 N V+ S+G + I + M + WVI + L +G+++ GK+ Y+T L PY +++ L Sbjct: 185 NFVVKPSTGFTDFNSINVPMLAAVAVCWVIAIISLIRGMKAIGKLSYYTVLLPYAIIIAL 244 Query: 270 FFRGVTLPGAITGI--LFYLTP------DFSQLANAQVWGDAAVQIFFALSPAWGGLITL 321 RG+TL GA TG+ LF+ P DF+ L + VW A +Q+ F+LS GGL+ + Sbjct: 245 MIRGLTLEGASTGLHFLFWGKPNEYGHYDFAGLYDPDVWIAALMQMCFSLSIGQGGLMNI 304 Query: 322 SSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSV------DRVVDQG 375 SYNK + N Y D+ +V + + S G +FS +GFLA + N+S+ + VV +G Sbjct: 305 GSYNKKTYNWYRDAYLVVLCDTLMSLLGGTAVFSTLGFLAEQRNISISNPKGFNEVVQEG 364 Query: 376 AGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKG 435 LAFIVY E + ++P LW LFFVML LG+ ++ ++ETV + + DRF RQ + Sbjct: 365 HALAFIVYTEAIAQMPYPFLWYALFFVMLFLLGISTEIVIIETVCSCLADRFHYLRQHRW 424 Query: 436 WVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCG 495 V V+ +L GL+ T+++G YW L D+Y+A S I C+ + W YG + F Sbjct: 425 ITVVTVSTTFFLLGLVMTSDAGFYWFDLYDEYSAGVSATIGTAIMCLTVCWCYGLDNFRA 484 Query: 496 DIQRMIGR-QSKL------WVYLWSAMWRIITP-AALVFILVFNWIEYKPASYGHYVYPM 547 DI+ M +S+L Y+W+ +WR +TP LV + + W + P YP Sbjct: 485 DIREMWEEPESRLDKYLGPGAYVWTIVWRFVTPICCLVIMFAWIWDKKYPFKGDSKKYPP 544 Query: 548 WADAVGW 554 DA GW Sbjct: 545 VFDAFGW 551 Score = 86.6 bits (205), Expect = 2e-15 Identities = 33/87 (37%), Positives = 55/87 (63%) Query: 48 NVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRG 107 N+WRFP Y NGG +FLI + V ++ +P + ME + GQYAA P A + + P+ G Sbjct: 87 NIWRFPTTAYKNGGLSFLIAYVVCGILFAVPAIHMEFALGQYAAKSPPAAFRRMMPILEG 146 Query: 108 LGYGMVIVSSIVMLYYNLIIAWTIFYM 134 +G+ +V +I+ +YY ++I+W + Y+ Sbjct: 147 VGWMTCLVGAIIGVYYMIVISWIVLYL 173 >UniRef50_Q2AHK9 Cluster: Transporter; n=1; Halothermothrix orenii H 168|Rep: Transporter - Halothermothrix orenii H 168 Length = 350 Score = 237 bits (579), Expect = 9e-61 Identities = 124/313 (39%), Positives = 186/313 (59%), Gaps = 12/313 (3%) Query: 236 AWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLA 295 +W+ ++L L KG +S GKVV +T + P V+L+IL R VTLPGAI G+ +YL PDF++L Sbjct: 2 SWIAIYLILRKGTESVGKVVPYTVILPVVLLLILIIRSVTLPGAIEGLNYYLKPDFTKLL 61 Query: 296 NAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFS 355 + VW DA Q+FF LS G +I +SY +++ ++LI +N SF AG+ +F Sbjct: 62 DIGVWIDAYTQVFFTLSLGMGIMIAYASYMPKNSDVVNNALITVFANSGVSFMAGIAVFG 121 Query: 356 VIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPL----WSILFFVMLLTLGLDS 411 +G++A E V++ VV G LAF+ YP + LP P+ + ++FFV LLTLG+DS Sbjct: 122 TLGYMAQEQGVAIADVVADGVILAFVTYPNAINMLPGGPIVAGFFGVVFFVTLLTLGIDS 181 Query: 412 QFALMETVTTAILDRFP-NFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAAN 470 F+L+E+ I+D++ N R+ WVV ++ V GLIF T +G+YWL L+D Y Sbjct: 182 AFSLVESNVAGIVDKWGFNRRKTTFWVVVLLLV----TGLIFATRAGLYWLDLIDHYVNT 237 Query: 471 WSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVF 530 + +L+ + E + I W Y AEK + Q W W+ M ++ITP LV++ VF Sbjct: 238 YGLLLGGLLEALAIGWFYNAEKLRNYFNPISEYQFGKW---WNIMVQVITPIILVYLFVF 294 Query: 531 NWIEYKPASYGHY 543 N + A+YG Y Sbjct: 295 NLSKDIGANYGGY 307 >UniRef50_UPI0000DC2074 Cluster: UPI0000DC2074 related cluster; n=1; Rattus norvegicus|Rep: UPI0000DC2074 UniRef100 entry - Rattus norvegicus Length = 491 Score = 236 bits (578), Expect = 1e-60 Identities = 138/486 (28%), Positives = 248/486 (51%), Gaps = 33/486 (6%) Query: 48 NVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRG 107 + WRFPYLC+ NGGG+FL+ + ++L++ G+PLM+ME+ GQ+ + + + P G Sbjct: 17 STWRFPYLCHQNGGGSFLLMYLILLLLLGIPLMYMEMVIGQWLRVDNIRAWKHLVPWLSG 76 Query: 108 LGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADE 167 +GY ++ ++V+LY + +++W++FY+ SF Y PW+NC S EE D Sbjct: 77 VGYSSMLACALVILYNSALVSWSLFYLGQSFD---YPTPWENCPLV--KNFSTSGEERD- 130 Query: 168 CEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIR- 226 G C N S LR P + ++ + VL S IEE E+ Sbjct: 131 --GGGG------CKNIS-------------CLRTEPHQFFWYHTVLRASDQIEEGIEVLV 169 Query: 227 LGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFY 286 L + +CL A W +++ + ++ S ++ F+ LFP V+L F + G + Sbjct: 170 LNVTLCLFATWFFLYITMVTRIKISVLMMIFSILFPNVLLFCFFTHIFFVKGVRDSLKRL 229 Query: 287 LTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATS 346 +T + S LA+ W A + ++L G +IT SSY N + VA+ N+ TS Sbjct: 230 VTTELSILASLDAWRQAGGHVLYSLGLGMGTIITFSSYQTRGENYIKWASFVAMVNLMTS 289 Query: 347 FFAGLVIFSVIGF-LAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLL 405 + VIF ++GF + + V+R +G GLA++ + + +T P S W+I+FF+ L+ Sbjct: 290 LLSSSVIFLMLGFWIENSGTPCVERQFMEGPGLAYVAFSQAITLFPGSSFWAIIFFMSLV 349 Query: 406 TLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMD 465 +GL + L+E + ++ + V I+ + G+LG L+F++ G Y + L D Sbjct: 350 IMGLGTMTTLVEGIALSLQKSISTLEKHPKLVPVIICLGGFLGSLVFSSRPGSYVVFLFD 409 Query: 466 KYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIIT-PAAL 524 + +++I + + +AW+YG ++F ++ +GR +W ++ +W +T P L Sbjct: 410 DHLVPMVLIMIVAFQNLSLAWVYGIKRFRAEMFGQLGR--LVWA-PFTFLWSYVTLPTLL 466 Query: 525 VFILVF 530 V + ++ Sbjct: 467 VLLTIY 472 >UniRef50_Q8IRU1 Cluster: Transporter; n=2; Diptera|Rep: Transporter - Drosophila melanogaster (Fruit fly) Length = 682 Score = 231 bits (565), Expect = 4e-59 Identities = 133/385 (34%), Positives = 200/385 (51%), Gaps = 41/385 (10%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 ER +W + F NVWRFPYL NGGGAFL+P+ +ML I G+P+ ++EL Sbjct: 53 ERESWDSKIMFLLATIGYAVGLGNVWRFPYLAQKNGGGAFLVPYFIMLCIQGIPIFYLEL 112 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 + GQ G + V+++ P G+G +VS IV ++Y T+ + Y Sbjct: 113 AIGQRLRKGAIGVWSQVSPYLGGIGISSAVVSYIV----------ALYYNTIIAWCLIYL 162 Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPA 204 L W+ +C + ++++ H +A + P Sbjct: 163 LHSFESPLPWA-----------DCPTR---------LYKNFTYDHEPECVASS-----PT 197 Query: 205 EEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264 + Y+ L S ++ MA+ L+ +W +V++C+ +G+ SSGK+VY TA+FPYV Sbjct: 198 QFYWYRTTLQCSESVDMPENFNYHMAIALIVSWFLVYICMVQGITSSGKIVYMTAIFPYV 257 Query: 265 VLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSY 324 VL+I FFRG+TL GA G+ TP + L + VW +A QIFF+L A+GGLI SSY Sbjct: 258 VLIIFFFRGITLKGAADGVAHLFTPRWETLLDPVVWLEAGTQIFFSLGLAFGGLIAFSSY 317 Query: 325 NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYP 384 N +NNCY D+++V+++N TS FAG+V+FSVIGF A + DR ++ GL V Sbjct: 318 NPANNNCYRDAILVSLTNCGTSMFAGVVVFSVIGFKA---TATFDRCTEERNGL---VAQ 371 Query: 385 EVVTRLPISPLWSILFFVMLLTLGL 409 LP+ L + L V L + L Sbjct: 372 NKTHNLPVCDLQTELANVSSLAICL 396 Score = 130 bits (314), Expect = 1e-28 Identities = 69/183 (37%), Positives = 108/183 (59%), Gaps = 10/183 (5%) Query: 375 GAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDR--FPNFRQ 432 G GLAFI++ E + + P + LW++LFF+ML TLG+DSQF +E V T+++D FPN Sbjct: 412 GTGLAFIIFTEAINQFPGAQLWAVLFFLMLFTLGIDSQFGTLEGVVTSLVDMKLFPNL-- 469 Query: 433 KKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEK 492 K ++V + + F +G Y QLMD +A N+ +LIIA+ EC+ I++IYG + Sbjct: 470 PKEYIVGALCFSCCTISMCFANGAGSYIFQLMDSFAGNFPLLIIALFECLSISYIYGVRR 529 Query: 493 FCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAV 552 F DI+ M G + + W W+ ++P A+V IL+ ++ Y+ + G YP W + Sbjct: 530 FSDDIEMMTGSRPN---FYWMFCWKYLSPCAMVTILLASF--YQLLTEGS-SYPAWIGSK 583 Query: 553 GWT 555 G T Sbjct: 584 GAT 586 >UniRef50_Q2QAU1 Cluster: Transporter; n=2; Didelphinae|Rep: Transporter - Didelphis marsupialis virginiana (North American opossum) Length = 618 Score = 231 bits (564), Expect = 6e-59 Identities = 124/339 (36%), Positives = 190/339 (56%), Gaps = 38/339 (11%) Query: 23 EPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFM 82 E ER W +F + N+WRFPYLC GGGAFLIP+ + L+ G+PL + Sbjct: 16 EDERPKWDNKFQYILSCVGFAVGLGNIWRFPYLCQTYGGGAFLIPYFIALIFEGIPLFHI 75 Query: 83 ELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIF 142 EL+ GQ G + V++ P +G+G G + VS +V +++Y T+ ++ Sbjct: 76 ELAIGQRLRTGSIGVWSTISPYLKGVGIGCLFVSFLV----------SLYYNTILMWVMW 125 Query: 143 YQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRP 202 Y L WS+ C E N T + +C S +V++ Sbjct: 126 YFLNSFQSPLPWSS--CPPNE--------NRTGLIEEC-QSSNAVNY------------- 161 Query: 203 PAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFP 262 ++ + L +++ I E+G ++ + MCL+A W+IV++C+ +G++++GK +YFTALFP Sbjct: 162 ----FWYRKTLNITTDINESGTLQWRLIMCLVACWMIVYICVIRGIETTGKAIYFTALFP 217 Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322 Y+VL I RG+TLPGA G+++ TP+ S L N QVW DAA QIFF+LS A+GG I S Sbjct: 218 YLVLTIFLIRGLTLPGATEGLIYLFTPNMSILQNPQVWLDAATQIFFSLSLAFGGHIAFS 277 Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLA 361 SYN N+C D++ +A+ N TS +A + +FSV+GF A Sbjct: 278 SYNPPKNDCEKDAVTIALVNSMTSLYASVAVFSVLGFKA 316 Score = 130 bits (314), Expect = 1e-28 Identities = 66/156 (42%), Positives = 95/156 (60%), Gaps = 4/156 (2%) Query: 375 GAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQ-K 433 G GLAFIV+ E + +P SP W++LFF ML +LGL S F ME V T ILD R Sbjct: 382 GTGLAFIVFTEAIVHMPGSPGWAVLFFGMLFSLGLTSMFGNMEGVLTPILDLQILPRSVP 441 Query: 434 KGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKF 493 K ++ ++ + L L FT SG YWL++ DKYAA+ ++L+ A E I + ++YG ++F Sbjct: 442 KEFITGVICLVCCLCALCFTLQSGSYWLEIFDKYAASLNLLVFAFFEVIGVIYVYGLKRF 501 Query: 494 CGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILV 529 C D++ M GR+ L+ W W+II+P L+ I V Sbjct: 502 CDDVEWMTGRRPNLY---WQVAWKIISPLLLLIIFV 534 >UniRef50_A1I9V5 Cluster: Sodium-and chloride-dependent transporter; n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: Sodium-and chloride-dependent transporter - Candidatus Desulfococcus oleovorans Hxd3 Length = 499 Score = 228 bits (558), Expect = 3e-58 Identities = 121/341 (35%), Positives = 194/341 (56%), Gaps = 7/341 (2%) Query: 204 AEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPY 263 ++ +F +L +S G + G I + L+ WV+++ + G+ GKV+ FT P Sbjct: 128 SKAHFFTDILHISEGPWQFGTIYPNLLWGLVTTWVVIWAIIRSGLSGIGKVLLFTVPLPV 187 Query: 264 VVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSS 323 ++++IL RG+TL G+ TG+ YLTPD+ +L + VW A QIFF+LS +G +I +S Sbjct: 188 ILVLILLVRGLTLEGSATGLNHYLTPDWGRLTDYHVWLAAYGQIFFSLSVGFGTMIAYAS 247 Query: 324 YNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVY 383 + + I + SN SF AGL +FSV+G+ A NV + V G GLAFIVY Sbjct: 248 FMPEDTELPNSAAITSFSNCCFSFLAGLAVFSVLGYFAVATNVPMTEVSQAGPGLAFIVY 307 Query: 384 PEVVTRLPI-SPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVA 442 P + +LP+ + LF + LL LG+DS F+L+ETV+ A+ D+F R I A Sbjct: 308 PAALAKLPVYVTFFGALFLITLLLLGIDSAFSLLETVSAALSDKFGITRSVS---TTITA 364 Query: 443 VFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIG 502 VF +L GL T +G+YWL +MD + ++++ +AI EC+ + WI GA+ F ++ R Sbjct: 365 VFSFLAGLPLATGAGIYWLDIMDHFIMSYAITTVAIVECLAVGWILGAKNFAAEVNRT-- 422 Query: 503 RQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHY 543 + K+ ++S + R +TPA L + ++ +++ A Y Y Sbjct: 423 AEIKIGP-IFSFIIRFLTPAILGYSVIRTFVDEMQAPYEGY 462 Score = 78.6 bits (185), Expect = 5e-13 Identities = 36/113 (31%), Positives = 55/113 (48%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 ER +W R F N+WRFPY+ NGGGAFLIP+ L+ AG+PLM +E Sbjct: 3 EREHWKNRSIFIMAAVGSAIGLGNMWRFPYIAAQNGGGAFLIPYMTALLTAGIPLMIIEY 62 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVS 137 G K R +G+ ++ + + +YY +++ WT ++ S Sbjct: 63 GLGIRTQGSAHIALGKIRKPLRFIGWMAILCALFINIYYCIVLGWTWNFLLAS 115 >UniRef50_Q9U2E3 Cluster: Transporter; n=1; Caenorhabditis elegans|Rep: Transporter - Caenorhabditis elegans Length = 600 Score = 227 bits (554), Expect = 9e-58 Identities = 114/312 (36%), Positives = 180/312 (57%), Gaps = 13/312 (4%) Query: 253 KVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLT-PDFSQLANAQVWGDAAVQIFFAL 311 K+ Y T + PY+++++L RGVTL GA G+ ++L D+ L N + W A Q+ F+L Sbjct: 213 KISYVTVILPYILIIVLLIRGVTLEGAGDGLKYFLARTDWVALYNFKTWSAALTQLCFSL 272 Query: 312 SPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRV 371 S +G L+ +SYNK ++ C+ D++ + + + A S G +FS +G+LA E V+VD+V Sbjct: 273 SIGFGVLMNTASYNKQNHRCFRDAIFLIIGDTAMSLIGGAAVFSTLGYLARERGVTVDKV 332 Query: 372 VDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFR 431 V G LAFI YP+ + ++P LWS LFF ML LG+ + ++E + T + D+FP R Sbjct: 333 VTDGTTLAFIAYPDAMNQMPFPGLWSFLFFFMLFLLGISTLLVIVEVMCTCLCDKFPRLR 392 Query: 432 QKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAE 491 +K+ +VV V +L G+I TT++G+YW L D+Y + + LI A CI+I++IYG Sbjct: 393 EKRVFVVIGVCFLLFLCGVILTTDAGIYWFALFDEYGSGFGALISATSMCIIISYIYGMR 452 Query: 492 KFCGDIQRMIGRQSKLW-VY-----LWSAMWRIITP---AALVFILVFNWIEYKPASYGH 542 F DI M+GR +++ ++ + W I P L+F+ +K S Sbjct: 453 NFRADIASMLGRGTRISNIFGHNSPYYGFNWMFIMPIFGCVLIFLTANRGYPFKGES--- 509 Query: 543 YVYPMWADAVGW 554 VYP+ D VGW Sbjct: 510 AVYPVVFDIVGW 521 Score = 68.1 bits (159), Expect = 7e-10 Identities = 35/94 (37%), Positives = 50/94 (53%), Gaps = 5/94 (5%) Query: 48 NVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRG 107 N+WRFP Y NGG FLIP+ ++ GLP +++E + GQY P VY + P G Sbjct: 119 NIWRFPSRAYENGGSVFLIPYITCALLFGLPGVYLEFAMGQYQGRSPPFVYRRIMPALEG 178 Query: 108 LGY---GMVIVSSIVMLYYNLIIAWTIFYMTVSF 138 G+ ++ S +L N I W IF + +SF Sbjct: 179 FGWVAANYIVKPSKGLLDIN-SINWPIF-IAMSF 210 >UniRef50_Q8MZ19 Cluster: Transporter; n=7; Endopterygota|Rep: Transporter - Drosophila melanogaster (Fruit fly) Length = 675 Score = 227 bits (554), Expect = 9e-58 Identities = 130/350 (37%), Positives = 180/350 (51%), Gaps = 42/350 (12%) Query: 23 EPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFM 82 EPER W+G+ F N+WRFPYLC NGGGAFLIPF VML++ G+PL + Sbjct: 52 EPERAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFLIPFMVMLILEGIPLFLI 111 Query: 83 ELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIF 142 EL GQ LG + V+N P G+G I S IV L+ ++Y + F Sbjct: 112 ELGIGQRMRLGALGVWNTIHPWLGGIG----ISSCIVTLFV------ALYYNVIITWVFF 161 Query: 143 YQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRP 202 Y WS+ C + L +C S + Sbjct: 162 YLFNSFRYPLPWSS-----------CPLNGTGFELEECAKSSETTY-------------- 196 Query: 203 PAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFP 262 ++ L + ++E G ++ + +CL+ +W IVF + KG+QSSGKVVYFT+LFP Sbjct: 197 ----FWYRTTLDAAPSMDEPGGLKWWIVLCLMLSWTIVFFIVMKGIQSSGKVVYFTSLFP 252 Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322 Y+VL I F RG+TL GA G++ TP +L VW DAA Q+F++ A+G LI Sbjct: 253 YIVLTIFFIRGITLRGAGAGLMHMYTPKVEKLLEPTVWLDAATQVFYSFGLAFGSLIAFG 312 Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVV 372 SYN NNC D L+V+V N T+ +A +VIF+++GF A V+VDR V Sbjct: 313 SYNTPKNNCVRDVLLVSVCNAVTAIYASVVIFAILGFKA---TVNVDRCV 359 Score = 126 bits (304), Expect = 2e-27 Identities = 68/171 (39%), Positives = 102/171 (59%), Gaps = 10/171 (5%) Query: 360 LAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETV 419 LAHEL+ + + G GLAFIV+ + + LP +P W++LFF MLL+LGL SQ ++E + Sbjct: 402 LAHELDNAAE-----GTGLAFIVFTQAIVELPGAPFWAVLFFTMLLSLGLGSQIGILEGM 456 Query: 420 TTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIG 479 + D R KK V +V +F ++ G IF T +G YWL++ D +A ++++A+ Sbjct: 457 LCTLFDIDIIKRVKKQHVTGVVCLFCFIVGFIFCTGAGEYWLKMFDSFAGTIGLVVVALM 516 Query: 480 ECILIAWIYGAEKFCGDIQRMIG-RQSKLWVYLWSAMWRIITPAALVFILV 529 E I + +IYG E+F DI +M G R + W W+ WR I P +V ILV Sbjct: 517 EMIAVIFIYGHERFTEDIFQMTGYRPGRYW--QWT--WRYIGPVIMVCILV 563 >UniRef50_UPI0000ECA0A4 Cluster: Orphan sodium- and chloride-dependent neurotransmitter transporter NTT4 (Solute carrier family 6 member 17).; n=1; Gallus gallus|Rep: Orphan sodium- and chloride-dependent neurotransmitter transporter NTT4 (Solute carrier family 6 member 17). - Gallus gallus Length = 439 Score = 225 bits (551), Expect = 2e-57 Identities = 109/249 (43%), Positives = 156/249 (62%), Gaps = 5/249 (2%) Query: 252 GKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFAL 311 G V+YF++LFPYVVLV RG+ L GA+ GI+ TP ++ + QVW +AA Q+FFAL Sbjct: 196 GVVMYFSSLFPYVVLVCFLVRGLLLRGAVDGIMHMFTPKLDKMLDPQVWREAATQVFFAL 255 Query: 312 SPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRV 371 +GG+I SSYNK NNC+ D+ +V+ N TS A LV+F+V+GF A+ +N V Sbjct: 256 GLGFGGVIAFSSYNKQDNNCHFDATLVSFINFFTSVLATLVVFAVLGFKANIMNEKC--V 313 Query: 372 VDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFR 431 V+QG GLAFI + E +T P SP WS++FF+ML+ LGL S M +TT I+D F+ Sbjct: 314 VEQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMSGITTPIID---TFK 370 Query: 432 QKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAE 491 +K +F ++ GLIF SG Y++ + D Y+A + ++ I E I +AWIYG + Sbjct: 371 VRKEVFTVGCCIFAFVVGLIFVQRSGNYFVTMFDDYSATLPLTVVVILENIAVAWIYGTK 430 Query: 492 KFCGDIQRM 500 KF ++ M Sbjct: 431 KFMQELTEM 439 Score = 133 bits (322), Expect = 1e-29 Identities = 60/132 (45%), Positives = 77/132 (58%), Gaps = 4/132 (3%) Query: 20 EEIEPE-RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLP 78 EE++ E R W + + NVWRFPYLC NGGGA+L+P+ V+L+I GLP Sbjct: 1 EELDAENRPAWNSKLQYILAQIGYSVGLGNVWRFPYLCQKNGGGAYLVPYLVLLIIIGLP 60 Query: 79 LMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSF 138 L F+EL+ GQ G + V+N CP G+GY +V V LYYN+II W+IFY F Sbjct: 61 LFFLELAVGQRIRRGSIGVWNYICPRLGGIGYASCLVCFFVGLYYNVIIGWSIFYF---F 117 Query: 139 SSIFYQLPWQNC 150 S Y LPW C Sbjct: 118 KSFQYPLPWSEC 129 >UniRef50_A3QK28 Cluster: Novel protein similar to vertebrate solute carrier family 6 (Neurotransmitter transporter), member 15; n=9; Danio rerio|Rep: Novel protein similar to vertebrate solute carrier family 6 (Neurotransmitter transporter), member 15 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 304 Score = 216 bits (527), Expect = 2e-54 Identities = 125/341 (36%), Positives = 180/341 (52%), Gaps = 40/341 (11%) Query: 29 WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQ 88 W + + NVWRFPYLC+ NGGGAF++ + ++L+I G+PL FMEL+ GQ Sbjct: 3 WDSKLQYVLAQVGFSVGLGNVWRFPYLCHQNGGGAFMLLYVMLLLIIGVPLFFMELAAGQ 62 Query: 89 YAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQ 148 G + V+ P G+GY +V V LYYN+IIAW++FYM SF Y LPW+ Sbjct: 63 SIRQGSIGVWKHISPRLAGIGYSSCMVCFFVALYYNVIIAWSLFYMGNSFQ---YPLPWE 119 Query: 149 NCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAEEYF 208 C + S + EC A + T Y F ++ +S +I + E+ Sbjct: 120 QCPVD-----MISNQTVKECAASSPTSYF--WFRKALDISDSI----------DQSGEF- 161 Query: 209 TNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVI 268 N ++ TG + A+ LA + KG++SS KV+YF+++FPY VL+ Sbjct: 162 -NPIM--------TGCLLAAWAIVCLA--------MIKGIKSSAKVMYFSSVFPYAVLIC 204 Query: 269 LFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFS 328 RG+ L GAI GI + P QVW AA Q+FFAL +G +I SSYN Sbjct: 205 FLIRGLMLDGAIDGIKYMFYPKVEIWGEVQVWRQAATQVFFALGLGYGSVIAYSSYNPIH 264 Query: 329 NNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVD 369 NNC+ D+++V+ N TS A LV+F V+GF A N+++D Sbjct: 265 NNCHRDAIMVSGINFMTSVLASLVVFVVLGFRAK--NIALD 303 >UniRef50_Q13032 Cluster: GABA/noradrenaline transporter; n=2; Homo sapiens|Rep: GABA/noradrenaline transporter - Homo sapiens (Human) Length = 732 Score = 213 bits (519), Expect = 2e-53 Identities = 100/188 (53%), Positives = 129/188 (68%) Query: 249 QSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIF 308 Q ++VYFTA FPYVVLV+L RGV LPGA+ GI++YL PD+S+L + QVW DA QIF Sbjct: 261 QPGPQIVYFTATFPYVVLVVLLVRGVLLPGALDGIIYYLKPDWSKLGSPQVWIDAGTQIF 320 Query: 309 FALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSV 368 F+ + G L L SYN+F+NNCY D++I+A+ N TSFFAG V+FS++GF+A E V + Sbjct: 321 FSYAIGLGALTALGSYNRFNNNCYKDAIILALINSGTSFFAGFVVFSILGFMAAEQGVHI 380 Query: 369 DRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFP 428 +V + G GLAFI YP VT +P++PLW+ LFF MLL LGLDSQ + R Sbjct: 381 SKVAESGPGLAFIAYPRAVTLMPVAPLWAALFFFMLLLLGLDSQVCMGLWDREPGGGRRE 440 Query: 429 NFRQKKGW 436 RQ KGW Sbjct: 441 GCRQGKGW 448 Score = 56.4 bits (130), Expect = 2e-06 Identities = 27/67 (40%), Positives = 38/67 (56%), Gaps = 4/67 (5%) Query: 489 GAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGH-YVYPM 547 GA++F DI MIG + W+ W W TP + I +FN + Y+P Y + YVYP Sbjct: 596 GADRFMDDIACMIGYRPCPWMK-WC--WSFFTPLVCMGIFIFNVVYYEPLVYNNTYVYPW 652 Query: 548 WADAVGW 554 W +A+GW Sbjct: 653 WGEAMGW 659 Score = 38.7 bits (86), Expect = 0.47 Identities = 16/34 (47%), Positives = 24/34 (70%), Gaps = 1/34 (2%) Query: 457 GMYWLQLMDKYAANWSVLII-AIGECILIAWIYG 489 GMY QL D Y+A+ + L+ A EC+++AW+YG Sbjct: 534 GMYVFQLFDYYSASGTTLLWQAFWECVVVAWVYG 567 >UniRef50_Q58715 Cluster: Uncharacterized sodium-dependent transporter MJ1319; n=6; Euryarchaeota|Rep: Uncharacterized sodium-dependent transporter MJ1319 - Methanococcus jannaschii Length = 492 Score = 210 bits (514), Expect = 6e-53 Identities = 113/339 (33%), Positives = 200/339 (58%), Gaps = 8/339 (2%) Query: 207 YFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSS-GKVVYFTALFPYVV 265 YF + +L +SSG+E+ G + G+ + LA W IV L L G+++ K F + Sbjct: 129 YFFHNILQISSGVEDIGGVSYGILVSTLAVWGIVALILSAGIKNGLEKANKIMIPFLLFL 188 Query: 266 LVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYN 325 +++L +TLPGA+TGI +YLTPDFS L N VW A QIFF+LS +G LI +SY Sbjct: 189 IILLVLNALTLPGALTGIEWYLTPDFSALFNYNVWLSAFSQIFFSLSLGFGILIAYASYL 248 Query: 326 KFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPE 385 ++ I+++ V++ N SF AG +F +G++++ + +D+ V +G GLAF+ +P+ Sbjct: 249 PKKSDLTINAVTVSLLNCGFSFLAGFAVFGTLGYMSYTSGIPLDKAVSEGIGLAFVTFPK 308 Query: 386 VVTRLPI-SPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVF 444 ++ LP S L+ I+FF+ L+ G+ S +++E +AI+D+F R+K ++ ++A+F Sbjct: 309 ALSLLPFASRLFGIVFFLALVFAGISSAVSIVEASVSAIIDKFSLSRKKA--LLAVLALF 366 Query: 445 GYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQ 504 + IFTT +G+Y+L ++D +A+ + + I AI E I+ W++G +K + ++ + Sbjct: 367 IIISP-IFTTGAGLYYLDIIDHFASGYLLPIAAILEIIIAIWLFGGDKLREHVNKL--SE 423 Query: 505 SKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHY 543 KL V+ W + +++P L ++ + + YG Y Sbjct: 424 IKLGVW-WKYLAGVVSPIILTAVVFLDASNVLTSGYGGY 461 Score = 89.0 bits (211), Expect = 3e-16 Identities = 40/112 (35%), Positives = 56/112 (50%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 ER +W+ F N+WRF Y+ Y NGGGAFLIP+ V L+ G+PLM +E Sbjct: 5 ERESWSSNLGFILASVGSAIGLGNIWRFGYMVYTNGGGAFLIPYIVALLCVGIPLMILEF 64 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTV 136 + G Y K G+ VI I+ YY +IIAW ++Y+ + Sbjct: 65 AIGHYTKKSAPLALEKLHKGSEWTGWFAVISGFIITSYYVVIIAWCLYYLII 116 >UniRef50_UPI0000E460AF Cluster: PREDICTED: similar to inebriated protein, partial; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to inebriated protein, partial - Strongylocentrotus purpuratus Length = 271 Score = 209 bits (511), Expect = 1e-52 Identities = 106/272 (38%), Positives = 153/272 (56%), Gaps = 25/272 (9%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 R W+ + F NVWRFPYLCY +GGGAFLIP+ + L + GLPL+ +E Sbjct: 24 REKWSNKAQFILACVGYAVGLGNVWRFPYLCYKSGGGAFLIPYFLTLFLTGLPLLLLEFG 83 Query: 86 FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQL 145 GQY GPV + K P+F+G G V+++ ++ YYN+I+ W +FY+ SF S+ L Sbjct: 84 LGQYIRYGPVEAFKKITPIFKGTGVATVMITFLLTTYYNVIMTWALFYLFASFQSV---L 140 Query: 146 PWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAE 205 PW C W+++ C+S ++ YL N++ + +I++ + Sbjct: 141 PWSQCNMTWNSEDCWSQDD-----------YLNLGPNET-QPNGSISS----------TQ 178 Query: 206 EYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVV 265 EYF ++VL +S GI+E +R + LL AWV+V+ CL KGV +SGKVVYFTA FPY+V Sbjct: 179 EYFDHRVLQISGGIDEPNGMRWELFGLLLLAWVLVYFCLFKGVATSGKVVYFTATFPYLV 238 Query: 266 LVILFFRGVTLPGAITGILFYLTPDFSQLANA 297 L++L G L GA GI F P + L A Sbjct: 239 LIVLLINGALLDGAGDGISFLFKPRWELLKKA 270 >UniRef50_Q9NP91 Cluster: Sodium- and chloride-dependent transporter XTRP3; n=19; Theria|Rep: Sodium- and chloride-dependent transporter XTRP3 - Homo sapiens (Human) Length = 592 Score = 206 bits (502), Expect = 2e-51 Identities = 153/544 (28%), Positives = 247/544 (45%), Gaps = 46/544 (8%) Query: 22 IEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMF 81 +E R W F NVWRFPYLC GGG+FL+P+ +ML++ G+PL++ Sbjct: 1 MEKARPLWANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLY 60 Query: 82 MELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSI 141 +EL+ GQ G + + P G+G V+VS + +YYN+I AW +Y+ SF Sbjct: 61 LELAVGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQD- 119 Query: 142 FYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYL--RQCFNQSYSVSHNITALAKTAL 199 LPW C + H Y+E ECE + T Y R+ N S S+ N + AL Sbjct: 120 --PLPWSVCPL--NGNHT-GYDE--ECEKASSTQYFWYRKTLNISPSLQENGGVQWEPAL 172 Query: 200 RRPPAEEYFTNQVLGLSSGIEETGEI---RLGMAMCLLAAWVIVFLCLCKGVQSSGKVVY 256 A + L + G E TG++ + C+L ++I L L G ++G + Sbjct: 173 CLLLA---WLVVYLCILRGTESTGKVVYFTASLPYCVLIIYLIRGLTL-HGA-TNGLMYM 227 Query: 257 FTALFPYVVLVILFFRGVTLPGAITGILF---YLTPDFSQLANAQVWGDAAVQIFFALSP 313 FT + + T G+ F +++ +N V + + + Sbjct: 228 FTPKIEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSLINSFTS 287 Query: 314 AWGGLITLSSYN---KFS-NNCY--IDSLIVAVSNIATSFFAGLVIFSVIGFLAHEL--- 364 + ++T S Y F+ NC + L+ ++ F + V G+LA Sbjct: 288 IFASIVTFSIYGFKATFNYENCLKKVSLLLTNTFDLEDGFLTASNLEQVKGYLASAYPSK 347 Query: 365 ---------NVSVDRVVD---QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQ 412 N S++ +D QG GLAFIVY E + + +S LWS+L+F MLL LG+ S Sbjct: 348 YSEMFPQIKNCSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGIGSM 407 Query: 413 FALMETVTTAILD-RFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANW 471 + T + D + + K + +V + G++FT +G YW + + YAA Sbjct: 408 LGNTAAILTPLTDSKIISSHLPKEAISGLVCLVNCAIGMVFTMEAGNYWFDIFNDYAATL 467 Query: 472 SVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFN 531 S+L+I + E I + ++YG +F D++ M GR + W MW ++P +V + VF Sbjct: 468 SLLLIVLVETIAVCYVYGLRRFESDLKAMTGRAVS---WYWKVMWAGVSPLLIVSLFVFY 524 Query: 532 WIEY 535 +Y Sbjct: 525 LSDY 528 >UniRef50_Q4SBR6 Cluster: Transporter; n=1; Tetraodon nigroviridis|Rep: Transporter - Tetraodon nigroviridis (Green puffer) Length = 361 Score = 203 bits (496), Expect = 1e-50 Identities = 107/273 (39%), Positives = 158/273 (57%), Gaps = 7/273 (2%) Query: 285 FYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIA 344 F P+ +VW DA Q+FF+ + G L +L SYNK++NNCY D L + N Sbjct: 18 FQPEPEKEPGCGPEVWADAGTQVFFSYAVCQGVLTSLGSYNKYNNNCYRDCLALCFLNSF 77 Query: 345 TSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVML 404 TS FAG +FSV+GF+AH L++S+ V G GLAFI YP+ ++ LP S W++LFF+M+ Sbjct: 78 TSIFAGFAVFSVLGFMAHGLDLSLPDVAVSGPGLAFIAYPKALSMLPGSSFWAVLFFLMI 137 Query: 405 LTLGLDSQFALMETVTTAILDRFPNFRQKKG---WVVFIVAVFGYLGGLIFTTNSGMYWL 461 L LGLD+QF +E++ T+I D FP +K G +V + + +L GL T G+ Sbjct: 138 LFLGLDTQFVCVESLATSITDLFPRQLRKPGARELLVLAITIVCFLLGLPLVTQGGIVLF 197 Query: 462 QLMDKYAANW-SVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIIT 520 QLMD + A+ ++L IA E I +AW+YGA++F +I+ MIG Q ++ W IT Sbjct: 198 QLMDTFGASGITLLFIACCETIAVAWVYGADRFYDNIEDMIGYQPLPFL---KYCWLFIT 254 Query: 521 PAALVFILVFNWIEYKPASYGHYVYPMWADAVG 553 P F +++N + + Y+ WA VG Sbjct: 255 PLICGFTMLYNLAQAQSIKVYGYLPGPWASVVG 287 >UniRef50_Q4AKJ6 Cluster: Transporter; n=4; Bacteria|Rep: Transporter - Chlorobium phaeobacteroides BS1 Length = 510 Score = 200 bits (487), Expect = 1e-49 Identities = 114/352 (32%), Positives = 190/352 (53%), Gaps = 13/352 (3%) Query: 205 EEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264 E +F L LSS E G I+ + LLA W+I + +GV S G + P + Sbjct: 130 EAFFFQSFLNLSSSPAEIGSIQTPILAGLLAVWLITWGISVRGV-SRGVELANRIFMPLL 188 Query: 265 VLV--ILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322 +++ IL F VTL GA+ GI YL PDF++LA+ VW A QIFF LS +G +I + Sbjct: 189 LILTLILVFWSVTLEGAMVGIAAYLQPDFTKLADPMVWISAYGQIFFTLSLGFGIMIAYA 248 Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIV 382 SY ++N +LI A++N S +G +F+V+GF++ N +D VV + GLAF+ Sbjct: 249 SYMPQNSNMTGSALITALANSGFSLLSGFGVFAVLGFMSVSRNQPLDEVVRESIGLAFVA 308 Query: 383 YPEVVTRL-PISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIV 441 YP+ ++ + PL+ +LFF+ L G+ S +++E + D+F R+K + ++ Sbjct: 309 YPKAISLIGDAGPLFGMLFFLSLTVAGISSSISIVEAFVSGAEDKFGINRKK---LSTVL 365 Query: 442 AVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMI 501 G++GG+IFTTN G++WL ++D + N+ +++ + ECI++ W + + + ++ Sbjct: 366 CFLGFVGGIIFTTNGGLFWLDIVDHFINNYGLVVAGLLECIVVGWFFNLDIIRKHLNKVS 425 Query: 502 GRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVG 553 Q W W+ + ++ P L IL+ I +YG Y WA +G Sbjct: 426 NMQLGTW---WNWIIKLCLPLFLSVILLNQLIRELFTAYGDY---SWASLIG 471 Score = 81.0 bits (191), Expect = 9e-14 Identities = 39/115 (33%), Positives = 57/115 (49%), Gaps = 1/115 (0%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 R W R F N+WRF YL Y NGGGAFLIP+ V L AG+PL+ +E Sbjct: 8 RSTWKSRSGFILAAIGSAVGLGNIWRFSYLTYENGGGAFLIPYLVALFTAGIPLLILEFG 67 Query: 86 FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSI-VMLYYNLIIAWTIFYMTVSFS 139 G + K + LG+ ++ + ++LYY ++IAW I ++ S + Sbjct: 68 IGHERIGSAPLAFRKIGRRWEWLGWWPLMFTMFGIVLYYAVVIAWCIDFIFYSIN 122 >UniRef50_UPI00015A63D4 Cluster: Sodium-dependent dopamine transporter (DA transporter) (DAT).; n=1; Danio rerio|Rep: Sodium-dependent dopamine transporter (DA transporter) (DAT). - Danio rerio Length = 589 Score = 199 bits (485), Expect = 2e-49 Identities = 117/336 (34%), Positives = 171/336 (50%), Gaps = 15/336 (4%) Query: 242 LCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWG 301 LC + VV+ TA PYVVL +L RGVTLPGAI GI YL+ DF +L + Sbjct: 232 LCKYDALMLYSDVVWITATMPYVVLTVLLLRGVTLPGAIDGIKAYLSVDFLRLYDVSGGV 291 Query: 302 DAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLA 361 AA AL + + C+ D++I + N TSFF+G VIFS +G+++ Sbjct: 292 SAAALCCVALCVCVCVCVCV---------CFRDAIITSSINSLTSFFSGFVIFSFLGYMS 342 Query: 362 HELNVSVDRVVDQGA-GLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVT 420 + NV++D+V G GL FI+YPE + LP S +W+++FF+MLLTLG+DS ME+V Sbjct: 343 QKHNVALDKVATDGRPGLVFIIYPEAIATLPGSSVWAVIFFIMLLTLGIDSAMGGMESVI 402 Query: 421 TAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGE 480 T ++D F + + + V +L LI TN G+Y L+D +AA S+L + E Sbjct: 403 TGLIDEFKFLHKHRELFTLFIVVSTFLISLICVTNGGIYVFTLLDHFAAGTSILFGVLIE 462 Query: 481 CILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASY 540 I IAW Y + F + S + ++ TP + F++V ++ + P Y Sbjct: 463 AIGIAWFYETDVFSDSVT----NHSSPSLQCSLSVQHHNTPQS-QFMVVISFATFNPPKY 517 Query: 541 GHYVYPMWADAVGWTXXXXXXXXXXXXXXDQICSGP 576 G Y +P WA VGW + CS P Sbjct: 518 GSYYFPTWATMVGWCLSISSMIMVPLYAIYKFCSLP 553 Score = 143 bits (346), Expect = 1e-32 Identities = 61/135 (45%), Positives = 85/135 (62%), Gaps = 5/135 (3%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 +R W + DF NVWRFPYLCY NGGGAFL+P+ +VIAG+PL +MEL Sbjct: 75 QRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLFFMVIAGMPLFYMEL 134 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 + GQY G V+ K CP+F+G+G+ ++++S V YYN+IIAW +FY+ SFS Sbjct: 135 ALGQYNREGAAGVW-KICPIFKGVGFTVILISLYVGFYYNVIIAWALFYLFSSFSG---- 189 Query: 145 LPWQNCKAEWSTKHC 159 PW +C W++ +C Sbjct: 190 EPWIHCNNTWNSPNC 204 >UniRef50_Q8TQM2 Cluster: Sodium/chloride-dependent noradrenaline transporter; n=1; Methanosarcina acetivorans|Rep: Sodium/chloride-dependent noradrenaline transporter - Methanosarcina acetivorans Length = 489 Score = 196 bits (478), Expect = 1e-48 Identities = 112/342 (32%), Positives = 188/342 (54%), Gaps = 14/342 (4%) Query: 207 YFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQS----SGKVVYFTALFP 262 +F N++L +S G + + LLA W+I+++ +GVQ+ S K+ F L Sbjct: 127 FFNNELLHVSDSPWNLGSFSYPVLIGLLATWLIIWVVEKRGVQAGIERSSKI--FIPLL- 183 Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322 +V+L++L FR +TL G+I GI +YL PDFS+L + +VW A Q F++LS +IT S Sbjct: 184 WVLLIVLVFRAITLEGSINGIEWYLKPDFSKLTDIKVWQAAYGQAFYSLSLGMAIMITYS 243 Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIV 382 SY ++ ++ IV++++ A SF G IF +G++A+ + ++ VV Q GLAF+V Sbjct: 244 SYLSKKSDIVNNAFIVSLADGAFSFTMGFAIFGTLGYMAYAKGLGIEEVVAQSIGLAFVV 303 Query: 383 YPEVVTRLP-ISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIV 441 PE + LP + L ++ FF+ + L S +L+E ++I+D+ F K+G V + Sbjct: 304 LPEALNMLPGLKALTAVAFFLCIAIAALSSLISLVEAFASSIMDK---FEVKRGKAVDLT 360 Query: 442 AVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMI 501 FG L LI+ T G+YWL ++D + + ++I+ I E + I WIYGA+K Sbjct: 361 IGFGLLFSLIYATRGGIYWLDIIDHFINTYGLIIVGILETVAIGWIYGADKIREWANNYS 420 Query: 502 GRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHY 543 + +W W A +++ P L++I+ + A Y Y Sbjct: 421 DIMAGIW---WDACIKLVIPVVLLYIVFVDTRSNLAAPYEGY 459 Score = 89.4 bits (212), Expect = 3e-16 Identities = 39/112 (34%), Positives = 63/112 (56%), Gaps = 2/112 (1%) Query: 29 WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFG- 87 W R F N+WRF Y+ Y NGGGAFLIP+ + L+ AG+PLM +E G Sbjct: 7 WNTRVGFILAAIGSAVGLGNIWRFSYMAYENGGGAFLIPYFIALLTAGIPLMILEFGLGS 66 Query: 88 QYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFS 139 ++ P++ + + F +G+ VI S I+ YY++I+ W++ Y+ +F+ Sbjct: 67 KFLGSAPLS-FKRAKKSFEWIGWWGVIASFIITTYYSVIVGWSLVYLLKAFT 117 >UniRef50_UPI00006CA50D Cluster: Sodium:neurotransmitter symporter family protein; n=3; Tetrahymena thermophila SB210|Rep: Sodium:neurotransmitter symporter family protein - Tetrahymena thermophila SB210 Length = 588 Score = 194 bits (474), Expect = 5e-48 Identities = 104/295 (35%), Positives = 161/295 (54%), Gaps = 7/295 (2%) Query: 200 RRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTA 259 ++P ++YF L SSG++E G I + C L + VIV+ C+ KGV SGK+ FTA Sbjct: 187 QKPWNKDYFYKNFLNSSSGLDELGGIVWPIFFCYLLSQVIVYFCIQKGVSVSGKIALFTA 246 Query: 260 LFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLI 319 PY++L IL RG+ L GA TGI + +PD+S+L++ QVW DAA QI F +S G LI Sbjct: 247 TSPYILLFILMLRGLFLEGAFTGISYLFSPDWSKLSDLQVWVDAANQIIFQVSTGCGVLI 306 Query: 320 TLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLA 379 SY S S +V + + F A VIFS +G+++H S+ + G LA Sbjct: 307 IFGSYRPVSQEIKQTSYMVPMLTVLCGFLASFVIFSFMGYMSHLTGQSIQDIPLSGPDLA 366 Query: 380 FIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFP-------NFRQ 432 F+V+P V+T +P S L SI+FF+ ++ LG+D+QFA M+ + +I D F N Sbjct: 367 FVVFPAVLTLMPFSNLLSIIFFLTMVFLGIDTQFAFMDGLAGSIEDEFHGTDAKIFNITI 426 Query: 433 KKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWI 487 + + + L +++T +G Y+L+ +D Y +++ E W+ Sbjct: 427 TQKHIRMGICSIVSLSAFLYSTQAGFYYLEFIDSYGVGINLITAVFMEVYFFNWM 481 Score = 98.3 bits (234), Expect = 5e-19 Identities = 45/129 (34%), Positives = 71/129 (55%), Gaps = 3/129 (2%) Query: 20 EEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPL 79 +E ER + +++ +VWRFPYL + NGGG FLIP+ + L + G P Sbjct: 54 DENHHERDRFNSYYEYLVSVLGFAAGFGSVWRFPYLIFKNGGGVFLIPYFIFLFLIGFPS 113 Query: 80 MFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFS 139 + E + GQ GP ++ K ++GLG V V+ + YYNLI+A++I+++ SF+ Sbjct: 114 FYFETAIGQIFQRGPPLIFEKIHKKWKGLGIFPVCVNFSMSTYYNLILAYSIYFLWKSFT 173 Query: 140 SIFYQLPWQ 148 Y LPW+ Sbjct: 174 ---YPLPWK 179 >UniRef50_Q4SNN5 Cluster: Transporter; n=1; Tetraodon nigroviridis|Rep: Transporter - Tetraodon nigroviridis (Green puffer) Length = 486 Score = 185 bits (450), Expect = 4e-45 Identities = 86/169 (50%), Positives = 116/169 (68%) Query: 211 QVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILF 270 ++L +S GIEE G + + +CLLA+WV + + KGV+S+GKV YFTA FPYV+L+IL Sbjct: 149 RMLRMSRGIEEVGSVSWELLLCLLASWVFCYFSIWKGVRSTGKVAYFTATFPYVMLLILL 208 Query: 271 FRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNN 330 RG+TLPGA GI FYL P+ L N +VW +A QI ++ S A G LI L SYNK++NN Sbjct: 209 IRGLTLPGAFDGIYFYLYPNLEDLTNLEVWIEAGSQICYSYSLAIGNLIVLGSYNKYNNN 268 Query: 331 CYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLA 379 CY D L + + N TSF AG V+FSV+GF+A + V++D V D G L+ Sbjct: 269 CYKDCLWICLLNSCTSFVAGFVVFSVLGFMAQKQGVTIDVVADSGQELS 317 Score = 130 bits (314), Expect = 1e-28 Identities = 55/131 (41%), Positives = 79/131 (60%), Gaps = 4/131 (3%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 RG W + ++ NVWRFPYLCY GGGAFLIP+T+++V+ G+PL +E S Sbjct: 15 RGQWASKTEYILVVAGNVVGLGNVWRFPYLCYRYGGGAFLIPYTLLVVVFGIPLFLLETS 74 Query: 86 FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQL 145 GQ+ G + + K CPL +G+GYG +++ + L Y +I AW +FY+ SF S +L Sbjct: 75 LGQFTQEGFITCWRKICPLAQGVGYGYLVL-KVYELVYIIIQAWALFYLVFSFRS---EL 130 Query: 146 PWQNCKAEWST 156 PW C W+T Sbjct: 131 PWATCNNSWNT 141 Score = 35.5 bits (78), Expect = 4.3 Identities = 19/67 (28%), Positives = 32/67 (47%), Gaps = 4/67 (5%) Query: 489 GAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGH-YVYPM 547 GA++ I IG++ ++ L W+ +TPA + + +Y+ YVYP Sbjct: 369 GADRLLDIIGDSIGQRPSVFFKL---CWKYVTPALSLISYILYLSDYRDLKINDWYVYPN 425 Query: 548 WADAVGW 554 WA +GW Sbjct: 426 WAYVLGW 432 >UniRef50_A0UVQ7 Cluster: Transporter; n=5; Clostridium|Rep: Transporter - Clostridium cellulolyticum H10 Length = 502 Score = 183 bits (446), Expect = 1e-44 Identities = 101/329 (30%), Positives = 181/329 (55%), Gaps = 11/329 (3%) Query: 228 GMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYL 287 G+ + L W + + + G++ K++ T + V ++I+ RGVTLPGA G+ Sbjct: 153 GITIIWLLNWFVCYKGVSGGIEKLNKILLPTLV---VAMIIIVIRGVTLPGASLGLNKLF 209 Query: 288 TPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSF 347 +PD+S++ + +VW A Q+FF+LS A G +IT SSY + + + A +N F Sbjct: 210 SPDWSKVLDPKVWIAAYGQVFFSLSLAMGIMITYSSYLPKKTDINNSAFMTAFANSGFEF 269 Query: 348 FAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRL-PISPLWSILFFVMLLT 406 + + +F+++G++A V VD+V QG GLAFI +P+V T + I L+ +LFF+ L+ Sbjct: 270 LSAIGVFAILGYMASTQGVGVDKVASQGIGLAFIAFPKVFTVMGGIGKLFGVLFFICLVF 329 Query: 407 LGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDK 466 G+ S +L+E ++A++D+ R+K VV +V + GY ++++T +G+Y+L ++D Sbjct: 330 AGITSSISLVEASSSALIDKTGAGRKK---VVSLVCLVGYSISIVYSTGAGLYFLDIIDN 386 Query: 467 YAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVF 526 + ++ ++ + + E I I W++GA K + W W+ M + ITP L F Sbjct: 387 FINSYGIVTVGLLEAITIGWLFGASKIREHTNAISYFSIGKW---WNVMVKFITPLILTF 443 Query: 527 ILVFNWIEYKPASYGHYVYPMWADAVGWT 555 +++ N + YG Y A GW+ Sbjct: 444 MIISNIVNEIIKPYGGYSQKALI-AFGWS 471 Score = 87.8 bits (208), Expect = 8e-16 Identities = 40/115 (34%), Positives = 60/115 (52%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 +R W + F N+WR+PY+ Y+NGGGAFLIP+ ++ AG+PLM ME Sbjct: 4 KRDQWGSKAGFILAAIGSAVGLGNIWRYPYVLYSNGGGAFLIPYFFAILTAGIPLMIMEY 63 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFS 139 G P + + + LG+ I S I++ YY LI++W I Y+ S + Sbjct: 64 GLGHKFKGSPPLAFARANKRWEWLGWWPSINSFIILTYYTLILSWAINYLYFSIT 118 >UniRef50_Q4RSW5 Cluster: Transporter; n=2; Tetraodontidae|Rep: Transporter - Tetraodon nigroviridis (Green puffer) Length = 616 Score = 183 bits (445), Expect = 1e-44 Identities = 102/268 (38%), Positives = 142/268 (52%), Gaps = 33/268 (12%) Query: 16 APLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIA 75 AP+ + + R W+ + DF NVWRFPY+CY NGGGAFLIP+ +M + Sbjct: 23 APVITQTD-SRDKWSKKMDFLLSVIGFAVDLGNVWRFPYICYQNGGGAFLIPYVLMAIFG 81 Query: 76 GLPLMFMELSFGQYAALGPVAVYNKFCPLFR-GLGYGMVIVSSIVMLYYNLIIAWTIFYM 134 G+PL +MEL+ GQ+ G ++++ CP+F+ G+GY + +++ V YYN IIAW +FY Sbjct: 82 GVPLFYMELAMGQFHRTGAISIWKHICPIFKGGIGYAICVIALYVSFYYNTIIAWALFYF 141 Query: 135 TVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITAL 194 SFSSI LPW NC W+T C +Y D NIT Sbjct: 142 YSSFSSI---LPWTNCDNVWNTPDCTNYFGRD-----------------------NIT-- 173 Query: 195 AKTALRRPPAEEYFTNQVLGL--SSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSG 252 T R PAEE++T VL L SSG++ G +R + +CL + IV+ L KGV++SG Sbjct: 174 -WTNFSRSPAEEFYTRNVLELHKSSGLKNVGGVRWQLMLCLFLIFTIVYFSLWKGVKTSG 232 Query: 253 KVVYFTALFPYVVLVILFFRGVTLPGAI 280 KV AL L+ TLPG + Sbjct: 233 KVAALEALVFSPALITHQMCTPTLPGGV 260 Score = 173 bits (422), Expect = 9e-42 Identities = 82/195 (42%), Positives = 129/195 (66%), Gaps = 4/195 (2%) Query: 298 QVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVI 357 QVW DAA QIFF+L P +G L+ LSSYN F+NNCY D+++ ++ N TSF +G VIF+V+ Sbjct: 325 QVWVDAAAQIFFSLGPGFGVLLALSSYNPFTNNCYRDAIVTSLVNCLTSFVSGFVIFTVL 384 Query: 358 GFLAHELNVSVDRVV-DQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALM 416 G++A V V+ V D+G L FI YPE + + S ++I+FFVM++ LGLDS F + Sbjct: 385 GYMAEMRKVEVEDVARDKGPSLLFITYPEAIANMMGSTFFAIIFFVMMIMLGLDSTFGGL 444 Query: 417 ETVTTAILDRFPN--FRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVL 474 E + TA+LD +P+ + +++ +V+ +V V +LG L TN G Y ++L++++ S++ Sbjct: 445 EAIITAVLDEYPDHLYHRRELFVLCLVVVC-FLGSLSTLTNGGAYVVKLLEEFGVGCSII 503 Query: 475 IIAIGECILIAWIYG 489 + E I ++W YG Sbjct: 504 ALGFLEAIAVSWFYG 518 >UniRef50_A0DZD7 Cluster: Transporter; n=3; Paramecium tetraurelia|Rep: Transporter - Paramecium tetraurelia Length = 533 Score = 181 bits (441), Expect = 5e-44 Identities = 99/305 (32%), Positives = 167/305 (54%), Gaps = 6/305 (1%) Query: 201 RPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTAL 260 +P + +YF + ++ +S+ I + I G+ + + + +IV+ C+ +GV++SGK+ TA Sbjct: 142 KPFSRDYFYDSIVQISTCITDLNHIIWGLFIAYIVSLIIVYFCIKEGVETSGKIAIVTAT 201 Query: 261 FPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLIT 320 PY++L+IL RG+ L G+ GI F PDF +L N VW DAA Q+ F +S L Sbjct: 202 SPYILLMILLIRGLMLEGSSEGIYFLFKPDFVKLFNPSVWVDAANQVIFQMSVGQAILCL 261 Query: 321 LSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAF 380 SY K +N S + + AGLV+FS IG ++ + NVS+ ++ G LAF Sbjct: 262 YGSYRKKDDNLSNFSFAIPLLTALCGMLAGLVVFSYIGHVSFKFNVSISQLPLSGPDLAF 321 Query: 381 IVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFI 440 ++YP ++ ++P+ LW ILFF++LL LG+D+QF ++ + I D + G+ + + Sbjct: 322 VLYPAILAQMPMPNLWCILFFLVLLMLGIDTQFGFVDGIAGTIEDIYLGEVIVCGYKLTV 381 Query: 441 ----VAVFGYLG--GLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFC 494 ++V LG GLI+ T+ G Y L +D + N S ++ + E EK Sbjct: 382 QQVRLSVCSILGVIGLIYCTDIGFYLLSFVDTFGTNVSFMLGVLFEVFYFGSKERFEKLK 441 Query: 495 GDIQR 499 D+++ Sbjct: 442 MDLEK 446 Score = 93.5 bits (222), Expect = 2e-17 Identities = 40/122 (32%), Positives = 68/122 (55%), Gaps = 3/122 (2%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 R ++ + F +VWRFPYL + NGGG FLIP+ +++ +PL F+E+ Sbjct: 15 RMKFSSSWTFMLTSLGFAAGFGSVWRFPYLVFKNGGGTFLIPYFILVFTLAIPLFFLEVG 74 Query: 86 FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQL 145 GQ +G + + P+ +G GY +++ + + YYNLI+A+++ Y+ SF Y + Sbjct: 75 LGQCKGIGMAHLLDIEKPMLKGFGYVGIVICAYISTYYNLIMAYSLRYLWESFK---YPI 131 Query: 146 PW 147 PW Sbjct: 132 PW 133 >UniRef50_Q1NTI5 Cluster: Transporter; n=2; delta proteobacterium MLMS-1|Rep: Transporter - delta proteobacterium MLMS-1 Length = 574 Score = 180 bits (437), Expect = 1e-43 Identities = 118/356 (33%), Positives = 185/356 (51%), Gaps = 27/356 (7%) Query: 205 EEYFTNQVLGLSSGIEETGEIR----LGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTAL 260 E +F Q L LS + G IR A LA W I + + G++ + K+ L Sbjct: 183 EGFFFGQFLQLSDSAGQLGGIRWPILAATAFIWLACWAICYRDIRHGIEKAAKLFMPLLL 242 Query: 261 FPYVVLVILFFRGVTLPGAITGILF-YLTPDFSQL-----------ANAQVWGDAAVQIF 308 +LV+ F TL GA GI+ YL+ D+S++ A QVW A QIF Sbjct: 243 LLTTILVVWVF---TLEGAREGIISNYLSADWSKINFLSGDAASRIAAGQVWVAAFGQIF 299 Query: 309 FALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSV 368 F LS +G +I +SY N +++I A +N S FAGL +F ++GF+AH V Sbjct: 300 FTLSLGFGIMIAYASYLPRQTNLARNAVITAAANCFYSIFAGLAVFGIVGFMAHSQGVGF 359 Query: 369 DRVVDQGAGLAFIVYPEVVTRLP-ISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRF 427 D + G LAF+VYP+ + LP + L+ LFF++L+ GL S +L+E T+A+ D++ Sbjct: 360 DDAIQGGPQLAFVVYPQAIYLLPDFNALFGALFFLVLIIAGLTSGVSLIEAFTSALTDKY 419 Query: 428 PNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWI 487 N+ +KK VV ++ + G LG +FT+ G+Y L ++D + N+ ++ + C+++ W Sbjct: 420 -NWSRKK--VVSVICLLGLLGSTLFTSRGGLYLLDIVDHFVTNYGLVGGGLLLCLVVGWY 476 Query: 488 YGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHY 543 G EK I R+ R S W W+ RI+TP L+ +L+ ++YG Y Sbjct: 477 SGPEKMRRHISRLGSRVSP-W---WNFFIRILTPLVLISLLLIALYGDLTSNYGDY 528 Score = 87.8 bits (208), Expect = 8e-16 Identities = 41/116 (35%), Positives = 65/116 (56%), Gaps = 3/116 (2%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 ER W F N+WRF Y+ + +GGGAFL+P+ V L++AG+PL+ +E Sbjct: 60 ERITWHSNIGFLMAAIGSAIGLGNIWRFSYMAHEHGGGAFLVPYLVALLVAGIPLILLEY 119 Query: 85 SFG-QYAALGPVAVYNKFCPLFRGLGYGMVIVSSI-VMLYYNLIIAWTIFYMTVSF 138 G + GP+A+ + F GLG+ M +V+ +MLYY++++ W + Y SF Sbjct: 120 GLGHREKGSGPLAL-ARINRRFEGLGWWMPVVAMFGIMLYYSVVMGWCVNYFFFSF 174 >UniRef50_O50649 Cluster: TnaT protein; n=1; Symbiobacterium thermophilum|Rep: TnaT protein - Symbiobacterium thermophilum Length = 501 Score = 173 bits (422), Expect = 9e-42 Identities = 97/344 (28%), Positives = 182/344 (52%), Gaps = 15/344 (4%) Query: 207 YFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVL 266 +F++ LG++SG E G +R G+ + W + +G+ S G + P++++ Sbjct: 128 FFSSDFLGITSGPLELGGLRWGIFAAVAVVWFANYYISAQGI-SGGIEKACKIMTPFLIV 186 Query: 267 VILFF--RGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSY 324 +L F RG+TLPGA G+ ++L PDFS++ + VW A Q+FF+ + A G +I +SY Sbjct: 187 AMLIFVIRGITLPGATYGLNYFLNPDFSKIMDPGVWVAAYSQVFFSTTLAVGVMIAYASY 246 Query: 325 NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYP 384 ++ ++ I +N + F AGL +FS +G+ A V + + G G+AF+ +P Sbjct: 247 VPEDSDLANNAFITVFANSSFDFMAGLAVFSTLGYAAVTAGVPFEEMAVAGPGVAFVAFP 306 Query: 385 EVVTRLP----ISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK-KGWVVF 439 + ++ LP + L+ ILFF LL G+ S + ME+ +A++DRF R+K GW Sbjct: 307 KAISMLPGPTWLQSLFGILFFSALLLAGISSSISQMESFASAVIDRFGVDRKKLLGW--- 363 Query: 440 IVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQR 499 ++ G+ +F T +G++ L ++D + ++++ I+ + E I++ +I G + + Sbjct: 364 -FSLIGFAFSALFATGAGVHILDIVDHFVGSYAIAILGLVEAIVLGYIMGTARIREHVNL 422 Query: 500 MIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHY 543 + +W W + + +TP L + ++ N+I Y Y Sbjct: 423 TSDIRVGMW---WDVLVKYVTPVLLGYNILSNFISEFREPYAGY 463 Score = 99 bits (238), Expect = 2e-19 Identities = 41/118 (34%), Positives = 65/118 (55%) Query: 22 IEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMF 81 +E +R W R F N WRFP++ Y NGGGAFL+P+ V L+ AG+PLM Sbjct: 1 MEAQRDQWKSRSGFIFATIGAAVGLGNFWRFPFMAYQNGGGAFLLPYFVALLTAGVPLMI 60 Query: 82 MELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFS 139 +E FG + + K F +G+ + V +V+ +Y++II+W++ Y+ SF+ Sbjct: 61 LEFGFGHKMRTATITAFKKLNRRFEWIGWWQITVPVVVVTFYSVIISWSLRYLIFSFT 118 >UniRef50_Q9KQI6 Cluster: Sodium-dependent transporter; n=34; Proteobacteria|Rep: Sodium-dependent transporter - Vibrio cholerae Length = 527 Score = 171 bits (415), Expect = 6e-41 Identities = 107/350 (30%), Positives = 178/350 (50%), Gaps = 17/350 (4%) Query: 207 YFTNQVLGLSSGIEET-GEIRLGMAMCLLAAWVIVFLCLC----KGVQSSGKVVYFTALF 261 YF ++ L L G I+ +A +L AWVI + + KG++ + K++ LF Sbjct: 167 YFFSEYLKLGDNSPTNLGSIQWHIAFAMLIAWVITYAAIVGGVKKGIERASKIM-MPILF 225 Query: 262 PYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITL 321 ++++IL R + LPGA+ G+ + PDFS++ + +VW A QIFF LS + ++ Sbjct: 226 --IMVLILIARMIFLPGALDGVNYMFQPDFSKIWDVKVWAAAYGQIFFTLSIGFAIMLAY 283 Query: 322 SSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFI 381 SSY ++ ++ + + N S AG++IFSV+G++A E + VV G GLAF+ Sbjct: 284 SSYLPEKSDITNNAFMTVLINCGFSVLAGIMIFSVLGYMAQEQGKPLTEVVSAGVGLAFV 343 Query: 382 VYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIV 441 P + LPI + LFF+ L+ GL S ++ME VT+A++D+ R+K IV Sbjct: 344 TLPAAINLLPIPYILGPLFFLALVVAGLSSHISIMEAVTSALIDKLGWSRKK---AANIV 400 Query: 442 AVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMI 501 G+L + F TN G+ L L+D +A N ++ + E +L+ W+ D+++ + Sbjct: 401 IGIGFLVSMAFATNGGLLLLDLVDHFANNVGIMASCLVELVLMTWLLK----ISDVRKYV 456 Query: 502 GRQSKLWVYLW-SAMWRIITPAALVFILVFNWIEYKPASYGHYVYPM-WA 549 S V +W R ++P L I+ YG Y + WA Sbjct: 457 NSISDFSVGVWFDICLRFVSPVILAIIVATKLQALFTEGYGGYDLTLGWA 506 Score = 94.3 bits (224), Expect = 9e-18 Identities = 44/130 (33%), Positives = 64/130 (49%) Query: 10 DEEKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFT 69 DE+ +E+ +R W R F N+WRFPY+ Y NGGGAF IP+ Sbjct: 28 DEKLHTLGYYKELFMKREQWGSRVGFVLAAVGSAIGLGNIWRFPYMAYENGGGAFFIPYL 87 Query: 70 VMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAW 129 +V AG+P M +E S GQ K F LG+ V +++++ +YY +I W Sbjct: 88 FAMVTAGIPFMILEFSMGQKHRGSAPTTLAKIHSKFEWLGWFQVGIAAVIAVYYVAVIGW 147 Query: 130 TIFYMTVSFS 139 I Y +SF+ Sbjct: 148 AISYFGMSFT 157 >UniRef50_A7RZ73 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 537 Score = 170 bits (414), Expect = 8e-41 Identities = 83/230 (36%), Positives = 128/230 (55%), Gaps = 19/230 (8%) Query: 24 PERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFME 83 P R +W + DF N WRFPYLCY +GG +FL P+ +ML + G+P+ FME Sbjct: 2 PRRESWNSKLDFFLATLGYIVGFGNFWRFPYLCYRSGGASFLFPYFLMLFVIGIPMFFME 61 Query: 84 LSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFY 143 LS GQ+ G V+V+ CPL GLGYG +++ + +YY +I+AW +FY+ SF S Sbjct: 62 LSVGQWYEAGMVSVWKAVCPLASGLGYGTLLMQLLSNIYYIVILAWVLFYLFDSFRS--- 118 Query: 144 QLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPP 203 +PW++C W+T C + A + + F + S T+ P Sbjct: 119 HVPWESCGNWWNTPFCRTQRTASQTVNCSA-------FALPVNCSQTFTS---------P 162 Query: 204 AEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGK 253 +EEY+TN+VL ++ +E+ GEIR + L+ +WV+V+ C+ K V+ +GK Sbjct: 163 SEEYWTNRVLQITDSLEDMGEIRWELVGTLILSWVLVYFCIFKSVRLTGK 212 Score = 99.1 bits (236), Expect = 3e-19 Identities = 55/144 (38%), Positives = 78/144 (54%), Gaps = 4/144 (2%) Query: 412 QFALMETVTTAILDRFPNFRQKKGWVVFI-VAVFGYLGGLIFTTNSGMYWLQLMDKYAAN 470 QF +E + T I+D +P + K W+V + + V L GL T GMY L D AA Sbjct: 360 QFGAIEALATGIIDEYPAKLRAKKWLVLLGLCVALGLLGLSCITQGGMYVFNLFDYQAAG 419 Query: 471 WSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVF 530 S+L + + E + IAWIYG ++F DI+ M G++ +WV L + ITPA I++ Sbjct: 420 LSLLFMVLLENVYIAWIYGMDRFSNDIEVMTGQKPYIWVTL---CLKYITPACSSAIILA 476 Query: 531 NWIEYKPASYGHYVYPMWADAVGW 554 N I + Y YP WA+AVGW Sbjct: 477 NMINWTGIKYDGRPYPGWAEAVGW 500 >UniRef50_UPI0000661366 Cluster: Sodium- and chloride-dependent glycine transporter 2 (GlyT2) (GlyT-2) (Solute carrier family 6 member 5).; n=2; Takifugu rubripes|Rep: Sodium- and chloride-dependent glycine transporter 2 (GlyT2) (GlyT-2) (Solute carrier family 6 member 5). - Takifugu rubripes Length = 268 Score = 170 bits (413), Expect = 1e-40 Identities = 78/110 (70%), Positives = 92/110 (83%) Query: 253 KVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALS 312 +VVYFTA FPYVVL+IL RGVTLPGA GIL+++TP + +L +A+VW DAA QIFF+LS Sbjct: 159 QVVYFTATFPYVVLIILLIRGVTLPGAFDGILYFITPKWEKLNDAKVWKDAATQIFFSLS 218 Query: 313 PAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAH 362 AWGGLITLSSYNKF NNCY D++IV +N ATS FAG VIFSVIGF+AH Sbjct: 219 AAWGGLITLSSYNKFHNNCYRDTVIVTCTNSATSIFAGFVIFSVIGFMAH 268 Score = 149 bits (361), Expect = 2e-34 Identities = 62/134 (46%), Positives = 90/134 (67%), Gaps = 4/134 (2%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 RGNW+ + DF NVWRFPYL + NGGGAFLIP+ ML IAG+P+ +E+S Sbjct: 6 RGNWSNKMDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLTMLGIAGIPIFLLEVS 65 Query: 86 FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQL 145 GQ+A+ GPV+V+ K P +G G M+I+S ++ +YYN+I+ WT++Y+ F+S+ L Sbjct: 66 LGQFASQGPVSVW-KCIPALQGCGIAMLIISVLIAIYYNIIMCWTLYYL---FASLKGSL 121 Query: 146 PWQNCKAEWSTKHC 159 PW NC+ +W+T C Sbjct: 122 PWANCRNDWNTVEC 135 >UniRef50_Q6PBA3 Cluster: Solute carrier family 6 (Neurotransmitter transporter), member 19; n=2; Danio rerio|Rep: Solute carrier family 6 (Neurotransmitter transporter), member 19 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 651 Score = 168 bits (409), Expect = 3e-40 Identities = 72/177 (40%), Positives = 116/177 (65%) Query: 187 VSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCK 246 ++ N T + P + ++ + L S+ I++TG +++ M +CL++AW ++++C + Sbjct: 156 INENRTGPIPECGKSSPVDYFWYRETLNTSAAIDDTGGLQVWMVLCLISAWAVLYVCCIR 215 Query: 247 GVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQ 306 G++++GK VY T+ PY+VL I RG+TL G++ GI F TPD ++LAN W DA Q Sbjct: 216 GIETTGKAVYVTSTLPYLVLTIFLIRGLTLKGSVDGIKFLFTPDINELANPSTWLDAGAQ 275 Query: 307 IFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHE 363 +F++ S A+GGLI+ SSYN NNC D++I++V N TS +A VI+S+IGF A E Sbjct: 276 VFYSFSLAFGGLISFSSYNSVHNNCEQDAVIISVINAFTSIYAATVIYSIIGFRATE 332 Score = 127 bits (307), Expect = 8e-28 Identities = 71/180 (39%), Positives = 103/180 (57%), Gaps = 7/180 (3%) Query: 353 IFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQ 412 I S + +LN + V+ G GLAFIV+ E +T++P+SPLWS+LFF+ML LGL S Sbjct: 375 IISSLSLKTCDLNNFLSEGVE-GTGLAFIVFTEAITKMPLSPLWSVLFFIMLFCLGLSSM 433 Query: 413 FALMETVTTAILDR--FPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAAN 470 F +E V + D FP K+ + + + L GLIF SG YWL L D +A + Sbjct: 434 FGNIEGVLVPLQDLGVFPKSWPKE-IISGVTCLVCCLVGLIFVQGSGNYWLALFDSFAGS 492 Query: 471 WSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVF 530 +LIIA E I + ++YG ++F D+ MIG + ++ W A WR I+P ++ I VF Sbjct: 493 IPLLIIAFSEMIGVVYVYGIDRFNEDLIFMIGHKPNIF---WQATWRFISPLIMLAIFVF 549 Score = 112 bits (269), Expect = 3e-23 Identities = 53/133 (39%), Positives = 72/133 (54%), Gaps = 3/133 (2%) Query: 18 LSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGL 77 L E +R W + + NVWRFPYLC ++GGGAF+IPF ++LV G+ Sbjct: 25 LEVEEAGDRPKWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVFEGI 84 Query: 78 PLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVS 137 PL+ +E + GQ G V V+ P G+G + VS +V LYYN IIAW ++Y Sbjct: 85 PLLHLEFAIGQRLRKGSVGVWRTINPYMLGVGIASMCVSFLVSLYYNTIIAWVMWYF--- 141 Query: 138 FSSIFYQLPWQNC 150 F+S LPW C Sbjct: 142 FNSFQDPLPWSQC 154 >UniRef50_O44752 Cluster: Sodium:neurotransmitter symporter family protein 1; n=2; Caenorhabditis|Rep: Sodium:neurotransmitter symporter family protein 1 - Caenorhabditis elegans Length = 617 Score = 167 bits (406), Expect = 8e-40 Identities = 134/543 (24%), Positives = 243/543 (44%), Gaps = 47/543 (8%) Query: 14 SKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLV 73 S L++ +E R W + +F N P L NGG AF + +++ Sbjct: 9 SNLRLTDLVEEWRDLWPSKIEFIVSAMAYLFAMTNFLNLPKLILENGGVAFAAAYAIVVG 68 Query: 74 IAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIV---MLYYNLIIAWT 130 + +P M ME+S GQ PV + P+FRG+G ++ + +V M + + Sbjct: 69 VLCMPTMVMEMSIGQVTGRAPVLAFYHLFPVFRGIGVSQILFTMVVLACMTKFLSTLCLF 128 Query: 131 IFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHN 190 ++Y +F + LPW NCKA + + C + Q N+ ++ Sbjct: 129 LYYYFWTFHAGRSGLPWLNCKA-------FPEFVSQPCREAGSITNITQINNRLNTIQAE 181 Query: 191 ITALA-KTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQ 249 + + T L RP S I + + + + + A W+ +F+ +C GV+ Sbjct: 182 SSMMQFLTTLERP-------------SESIADFKDFQYPILIAQGAIWIAIFVAICFGVR 228 Query: 250 SSGKVVYFTALFPYVVLVILFFRGVTLPGAITGIL--FYLTPDFSQLANAQVWGDAAVQI 307 GK V F + + L++ F R TL G +T IL ++ D+ +LA+ QVW A Q Sbjct: 229 FVGKTVAFVLMLAFSSLLVFFLRSATL-GGVTEILEIYWKATDWEKLADYQVWRLAIEQA 287 Query: 308 FFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVS 367 +G IT+SSY K SNN DS+ ++V ++ SF + I ++G+L+ +L + Sbjct: 288 ILGTGIGYGAFITMSSYMKRSNNLVCDSIFLSVWHLIISFVQTMSIICIVGYLSMKLGIH 347 Query: 368 VDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRF 427 +++ G + + V+ LP LWS +LLT+ + + F+++ + ++L F Sbjct: 348 PTELLETGEDQMWYML-AYVSYLP--KLWS----GVLLTICICTMFSVITILALSVLSTF 400 Query: 428 PN-FRQ------KKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGE 480 + F + ++ ++ V +F + + F TN+G + +L + ++ I E Sbjct: 401 EDAFGENWSKCCRRFFLALFVCLFCFGLTVYFATNAGRHAYELATRSIKYCTIYFILTAE 460 Query: 481 CILIAWIYGAEKFCGDIQRMI-GRQSKLW--VYLWSAMWRIITPAALVFILVFNWIEYKP 537 AW Y A K D+ M+ R + +L+ I PA + F+ N ++YK Sbjct: 461 LFATAWFYCAHKLGKDLHNMMRSRCCSCFGHFFLYFTYLLPILPAGVAFL---NALDYKF 517 Query: 538 ASY 540 +S+ Sbjct: 518 SSF 520 >UniRef50_Q695T7 Cluster: Sodium-dependent neutral amino acid transporter B(0) (System B(0) neutral amino acid transporter) (B(0)AT1); n=36; Euteleostomi|Rep: Sodium-dependent neutral amino acid transporter B(0) (System B(0) neutral amino acid transporter) (B(0)AT1) - Homo sapiens (Human) Length = 634 Score = 165 bits (401), Expect = 3e-39 Identities = 73/175 (41%), Positives = 111/175 (63%) Query: 187 VSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCK 246 ++ N T R P + ++ + L +S+ I ++G I+ M +CL AW ++++C + Sbjct: 155 LNENQTGYVDECARSSPVDYFWYRETLNISTSISDSGSIQWWMLLCLACAWSVLYMCTIR 214 Query: 247 GVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQ 306 G++++GK VY T+ PYVVL I RG+TL GA GI+F TP+ ++LA W DA Q Sbjct: 215 GIETTGKAVYITSTLPYVVLTIFLIRGLTLKGATNGIVFLFTPNVTELAQPDTWLDAGAQ 274 Query: 307 IFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLA 361 +FF+ S A+GGLI+ SSYN NNC DS+IV++ N TS + +V++SVIGF A Sbjct: 275 VFFSFSLAFGGLISFSSYNSVHNNCEKDSVIVSIINGFTSVYVAIVVYSVIGFRA 329 Score = 139 bits (336), Expect = 2e-31 Identities = 68/181 (37%), Positives = 109/181 (60%), Gaps = 5/181 (2%) Query: 354 FSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQF 413 ++ + F ++N + V+ G GLAFIV+ E +T++P+SPLWS+LFF+ML LGL S F Sbjct: 375 YAQLVFQTCDINAFLSEAVE-GTGLAFIVFTEAITKMPLSPLWSVLFFIMLFCLGLSSMF 433 Query: 414 ALMETVTTAILD-RFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWS 472 ME V + D R + K + ++ + +L G IFT NSG YWL L+D YA + Sbjct: 434 GNMEGVVVPLQDLRVIPPKWPKEVLTGLICLGTFLIGFIFTLNSGQYWLSLLDSYAGSIP 493 Query: 473 VLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNW 532 +LIIA E + ++YG ++F DI+ MIG + ++ W WR+++P ++ I +F + Sbjct: 494 LLIIAFCEMFSVVYVYGVDRFNKDIEFMIGHKPNIF---WQVTWRVVSPLLMLIIFLFFF 550 Query: 533 I 533 + Sbjct: 551 V 551 >UniRef50_Q9H2J7 Cluster: Orphan sodium- and chloride-dependent neurotransmitter transporter NTT73; n=70; Euteleostomi|Rep: Orphan sodium- and chloride-dependent neurotransmitter transporter NTT73 - Homo sapiens (Human) Length = 730 Score = 164 bits (398), Expect = 7e-39 Identities = 75/159 (47%), Positives = 106/159 (66%) Query: 207 YFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVL 266 Y+ + L +SS I E+G + M +CLLAAWV+V L + KG+QSSGK++YF++LFPYVVL Sbjct: 206 YWYREALNISSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKIIYFSSLFPYVVL 265 Query: 267 VILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNK 326 + R L G+I GI TP + +VW +AA Q+FFAL +GG+I SSYNK Sbjct: 266 ICFLIRAFLLNGSIDGIRHMFTPKLEIMLEPKVWREAATQVFFALGLGFGGVIAFSSYNK 325 Query: 327 FSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELN 365 NNC+ D+++V+ N TS A LV+F+V+GF A+ +N Sbjct: 326 RDNNCHFDAVLVSFINFFTSVLATLVVFAVLGFKANVIN 364 Score = 142 bits (345), Expect = 2e-32 Identities = 67/183 (36%), Positives = 97/183 (53%), Gaps = 5/183 (2%) Query: 9 GDEEK-SKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIP 67 G EEK + E+E ER W + + NVWRFPYLC NGGGA+L+P Sbjct: 43 GQEEKDTDVEEGSEVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLP 102 Query: 68 FTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLII 127 + ++L++ G+PL F+ELS GQ G + V+N P G+G+ +V V LYYN+II Sbjct: 103 YLILLMVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVII 162 Query: 128 AWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSV 187 W++FY + SF LPW C + H + E ++ A Y+ R+ N S S+ Sbjct: 163 GWSLFYFSQSFQQ---PLPWDQCPLVKNASHTFVEPECEQSSATT-YYWYREALNISSSI 218 Query: 188 SHN 190 S + Sbjct: 219 SES 221 Score = 120 bits (289), Expect = 1e-25 Identities = 61/173 (35%), Positives = 98/173 (56%), Gaps = 8/173 (4%) Query: 374 QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK 433 QG GLAFI + E +T P SP WS++FF+ML+ LGL S F +E + T I+D F+ + Sbjct: 437 QGTGLAFIAFTEAMTHFPASPFWSVMFFLMLVNLGLGSMFGTIEGIVTPIVD---TFKVR 493 Query: 434 KGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKF 493 K + I + + GLIF SG Y++ + D Y+A +LI+ I E I + ++YG +KF Sbjct: 494 KEILTVICCLLAFCIGLIFVQRSGNYFVTMFDDYSATLPLLIVVILENIAVCFVYGIDKF 553 Query: 494 CGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIE--YKPASYGHYV 544 D++ M+G + Y MW+ I+P L+ +L+ + + P Y ++ Sbjct: 554 MEDLKDMLGFAPSRYYYY---MWKYISPLMLLSLLIASVVNMGLSPPGYNAWI 603 >UniRef50_Q8ENV8 Cluster: Sodium-dependent transporter; n=18; Bacteria|Rep: Sodium-dependent transporter - Oceanobacillus iheyensis Length = 511 Score = 161 bits (392), Expect = 4e-38 Identities = 104/328 (31%), Positives = 170/328 (51%), Gaps = 9/328 (2%) Query: 205 EEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVV--YFTALFP 262 E + L L+ + G + G+ + L+ WV+V L +GV+ +V F L Sbjct: 125 EGFLFGDYLNLAEVPGQVGGLVPGVLIPLIIVWVLVLGILFRGVKKGIEVANRIFIPLLV 184 Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322 V LVI+ R VTLPGA G+ + TPDFS++ VW A QIFF+LS A+ +IT S Sbjct: 185 LVFLVIVI-RAVTLPGAAEGLNAFFTPDFSRILEPDVWIAAYGQIFFSLSIAFAIMITYS 243 Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIV 382 SY ++ ++ IV N AG+ +F V+GF+A V VD VV G GLAF+V Sbjct: 244 SYLPKKSDITNNAFIVGFGNSGFELLAGIGVFGVLGFMATSSGVGVDEVVAGGVGLAFVV 303 Query: 383 YPEVVTRLP-ISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIV 441 +P ++ LP + L+ LFFV L G+ S ++ E +A++D+F R K V+F Sbjct: 304 FPAIINELPAFNGLFGALFFVSLTLAGITSLVSITEAYVSALVDKFKITRTKA--VLFGG 361 Query: 442 AVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMI 501 + + L+F + G+++L ++D + + V ++ + E +LIAWI + Sbjct: 362 GLAAVI-SLLFASRGGLHFLDVVDYFINQFGVAMLGLVEVVLIAWILRKSNVLKSHANSV 420 Query: 502 GRQSKLWVYLWSAMWRIITPAALVFILV 529 +L + W+ +ITP + ++++ Sbjct: 421 S-DIRLGSW-WTICLTVITPIVMGYMML 446 Score = 85.0 bits (201), Expect = 5e-15 Identities = 39/115 (33%), Positives = 62/115 (53%), Gaps = 2/115 (1%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 R W R F N+WRFP + Y +GGGAF IP+ L+ AG+P++ ME + Sbjct: 4 RSQWGTRAGFILAAVGSAVGLGNIWRFPSVAYESGGGAFFIPYLFALLTAGIPILIMEFT 63 Query: 86 FG-QYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFS 139 G +Y P+ +++ +G+ V+V+ ++ YY++IIAW I Y SF+ Sbjct: 64 MGHKYRGSAPL-TFSRMNKKAEFVGWWAVLVAFVISTYYSVIIAWAISYSIFSFN 117 >UniRef50_Q1RLZ0 Cluster: Transporter; n=21; Euteleostomi|Rep: Transporter - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 660 Score = 161 bits (391), Expect = 5e-38 Identities = 71/177 (40%), Positives = 110/177 (62%) Query: 187 VSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCK 246 V+ N T L R P + ++ + L S+ IE++G ++ + +CLL AW +++C + Sbjct: 185 VNLNRTGLVSECERSSPVDYFWYRETLNTSTAIEDSGALQWWLVLCLLCAWTFLYICCIR 244 Query: 247 GVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQ 306 G++++GK VY T+ PYVVL I R +TL G++ GI F TPD ++L N W DA Q Sbjct: 245 GIETTGKAVYITSTLPYVVLTIFLIRALTLKGSVNGIKFLFTPDVNELMNPSTWLDAGAQ 304 Query: 307 IFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHE 363 + F+ S A+GGLI+ SSYN NNC D++ +++ N TS ++ VI+S+IGF A E Sbjct: 305 VLFSFSLAFGGLISFSSYNSVHNNCEQDAVTISIINGLTSVYSATVIYSIIGFRATE 361 Score = 130 bits (315), Expect = 8e-29 Identities = 63/162 (38%), Positives = 99/162 (61%), Gaps = 6/162 (3%) Query: 374 QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAI--LDRFPNFR 431 +G GLAFIV+ E +T++P+SPLWS+LFF+ML LGL + F +E V + L+ P R Sbjct: 424 EGTGLAFIVFTEAITKMPVSPLWSVLFFIMLFCLGLSTMFGNIEGVVVPLQDLNLLPK-R 482 Query: 432 QKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAE 491 K + V +L L+F +SG YWL L D +A + +L+IA+ E I + ++YG + Sbjct: 483 WPKEVFTGLTCVVSFLTALVFVQSSGNYWLALFDGFAGSIPLLVIALCELIAVVYVYGID 542 Query: 492 KFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWI 533 +F DI+ M+G + ++ W WR ++P L+ IL+F +I Sbjct: 543 RFNEDIKFMVGHKPNIF---WQISWRFLSPVILLVILIFYFI 581 Score = 115 bits (277), Expect = 3e-24 Identities = 57/165 (34%), Positives = 87/165 (52%), Gaps = 10/165 (6%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 ER W + + NVWRFPYLC ++GGGAF+IPF ++LV+ G+PL+ +E Sbjct: 61 ERPKWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGVPLLHLEF 120 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 + GQ G V V+ P G+G ++ S IV +YYN I+AW ++Y+ F+S+ Sbjct: 121 AIGQRLRSGSVGVWRSISPYLTGVGIASMLASFIVGMYYNTIMAWVMWYL---FNSLQEP 177 Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGT--YYLRQCFNQSYSV 187 LPW C + S ECE + ++ R+ N S ++ Sbjct: 178 LPWSQCPVNLNRTGLVS-----ECERSSPVDYFWYRETLNTSTAI 217 >UniRef50_Q4SIS1 Cluster: Transporter; n=1; Tetraodon nigroviridis|Rep: Transporter - Tetraodon nigroviridis (Green puffer) Length = 614 Score = 161 bits (390), Expect = 7e-38 Identities = 106/353 (30%), Positives = 172/353 (48%), Gaps = 24/353 (6%) Query: 18 LSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGL 77 + +E +R W + + NVWRFPYLC ++GGGAF+IPF ++LV+ G+ Sbjct: 27 MEKEEAGDRPKWDNKAQYLLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGI 86 Query: 78 PLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVS 137 PL+ +E + GQ G V+ P G+G ++VS +V +YYN I+AW ++Y+ Sbjct: 87 PLLHLEFAIGQRLRKGSTGVWRSINPYLTGIGVASLLVSFLVGMYYNTIMAWIMWYL--- 143 Query: 138 FSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGT---YYLRQCFNQSYSVSHNITAL 194 F+S LPW C + +EC A++ T ++ R+ N S S+ + Sbjct: 144 FNSFQDPLPWSQCPLNENRTGL-----VEEC-ARSSTVDYFWYRETLNTSTSIEDSGGLQ 197 Query: 195 AKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKV 254 L A +T + GIE +G+ + + ++++ + L +G+ G V Sbjct: 198 WWIVLALVAA---WTLLYVCCIRGIETSGK---AVYITSTLPYLVLTIFLVRGLTLKGSV 251 Query: 255 VYFTALF-PYVVLVILFFRGVTLPGAITGILFYLTPDF-----SQLANAQVWGDAAVQIF 308 LF P V + R +L F +L N W DA Q+F Sbjct: 252 EGLKFLFTPKVSACVTRVRHHCWRRHPEALLCETNRAFCSFQVEELINPATWLDAGAQVF 311 Query: 309 FALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLA 361 ++ S A+GGLI+ SSYN NNC D++++++ N TS ++ VI+S+IGF A Sbjct: 312 YSFSLAFGGLISFSSYNSVHNNCEQDAVLISIINGCTSVYSATVIYSIIGFRA 364 Score = 80.2 bits (189), Expect = 2e-13 Identities = 35/85 (41%), Positives = 53/85 (62%), Gaps = 3/85 (3%) Query: 449 GLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLW 508 GLIF T SG YWL L D +A + +L+I E I + +IYG ++F DI+ M+G + ++ Sbjct: 532 GLIFATRSGNYWLALFDNFAGSIPLLVIGFSEMISVIYIYGIDRFNKDIEFMVGHKPNIF 591 Query: 509 VYLWSAMWRIITPAALVFILVFNWI 533 W WR I+P ++FILVF ++ Sbjct: 592 ---WQVTWRFISPLIMIFILVFYFV 613 Score = 63.7 bits (148), Expect = 1e-08 Identities = 26/52 (50%), Positives = 37/52 (71%) Query: 374 QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILD 425 +G GLAFIV+ E + ++P+SPLW++LFFVML LGL + F +E V + D Sbjct: 429 EGTGLAFIVFTEAIIKMPVSPLWAVLFFVMLFCLGLSTMFGNIEGVVVPLQD 480 >UniRef50_O45915 Cluster: Transporter; n=2; Caenorhabditis|Rep: Transporter - Caenorhabditis elegans Length = 673 Score = 157 bits (382), Expect = 6e-37 Identities = 122/522 (23%), Positives = 237/522 (45%), Gaps = 33/522 (6%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 E WT +++ N+W FPYLC GG F FT V +PL+++E Sbjct: 76 EGPTWTSKWEAITATLSFVTCSGNIWFFPYLC-GYYGGWFPYQFTFCYVFIAVPLLYLET 134 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTV---SFSSI 141 + GQYA+ P++V+++ P GL GM + +V +L + W I+ +T+ + SI Sbjct: 135 ALGQYASASPLSVFSRMAPAMAGLSAGMCFI--MVFRTISLSV-WAIYDLTIFTHASQSI 191 Query: 142 FYQLPWQNCKAEWSTKHCYSYEEADECE-AQNGTYYLRQCFNQSYSVSHNITALAKTALR 200 + PW++C+ S +C +Y+ + +C Q G+ ++C Y + A R Sbjct: 192 WSTSPWESCQESQSGDYCVNYKLSSKCTWIQPGSD--KEC--DEY--QEMLIATRGFQQR 245 Query: 201 RPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGK--VVYFT 258 + P + + S + + + +C + W+I+ + G + G+ +V T Sbjct: 246 KSPFMSFVHGLMYKRSITMNDWEPPSVTSIICAVCLWIIIGIISIGGSKVLGRTGIVALT 305 Query: 259 ALFPYVVLVILFFRGVTLPGAITGILFYLTPDF-SQLANAQVWGDAAVQIFFALSPAWGG 317 L ++++ + + + FY + + + W DAA AL+ GG Sbjct: 306 LLLVGTIMLLSYGMSLNDTTNVFTAFFYQSEGYEDKWMWVWSWADAAAHALRALNVGCGG 365 Query: 318 LITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIF---SVIGFLAH-ELNVSVDRVVD 373 + +S N F N + D L++++ + GL+ F + IG L + +L S + Sbjct: 366 IQKFASLNNFHNKIHRDVLLISIVSFVFYICTGLLSFMFMAEIGRLYYPDLEASERIQLY 425 Query: 374 QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK 433 + V E++T + +W LF++ L + + + +++ I++R R+K Sbjct: 426 ATPVMIESVISEILTNSSMGSIWVFLFWLTLAACSIQGISSYIWVISSMIVERLNGSRRK 485 Query: 434 KG-----W-----VVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECIL 483 G W ++ I++V G + L F N G+ + ++ + A++ + IA E I Sbjct: 486 YGKALASWHKRAIILAIMSVTGLISSLPFLGNGGINLMSSIETF-ASYGTIFIAFVEVIT 544 Query: 484 IAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALV 525 ++++YG ++F +I+ MIG V+ W W +I+P L+ Sbjct: 545 VSYVYGFKRFSVNIRAMIGGHGPPNVFWW-LNWLVISPILLI 585 >UniRef50_A4AIT5 Cluster: Transporter; n=1; marine actinobacterium PHSC20C1|Rep: Transporter - marine actinobacterium PHSC20C1 Length = 527 Score = 155 bits (376), Expect = 3e-36 Identities = 98/329 (29%), Positives = 176/329 (53%), Gaps = 17/329 (5%) Query: 233 LLAAWVIVFLCL----CKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLT 288 L+ WV V L KGVQ + +++ L V +IL R + L GA++G+ + T Sbjct: 170 LVLVWVAVLAVLGSGIAKGVQRAN-IIFLPLLV--VAFLILVVRALFLDGAMSGLNAFFT 226 Query: 289 PDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFF 348 PDF+ L + VW A QIFF+LS A+G +IT SSY N +L+VA +N + Sbjct: 227 PDFTALGDPNVWIAAYSQIFFSLSIAFGIMITYSSYRSRKANVTAPALVVAFANSSFEII 286 Query: 349 AGLVIFSVIGFLAHELNVSVDRVVD-QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTL 407 AG+ +F+ +G+ A + V++D + G GL+FI +P +V+++P P++ LFF L+ Sbjct: 287 AGIGVFATLGYFAFQQGVAIDELEGLTGVGLSFITFPAIVSQMPGGPIFGALFFGSLVMA 346 Query: 408 GLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKY 467 G S ++++ V++A D+F ++ + + + + L+F+T +G+ L +D++ Sbjct: 347 GFTSLLSVLQVVSSAFQDKFGITARQA--ALRVGSALAIVSVLLFSTTTGLITLDTVDQW 404 Query: 468 AANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWV-YLWSAMWRIITPAALVF 526 A N ++ AI IL+ W++ + ++ + S V +W + ++ P L++ Sbjct: 405 ANNVGIVGAAIAATILVIWVF---RKGPELAAHLSAVSTFRVGRVWQLLVGVLAPVVLLY 461 Query: 527 ILVFNWIEYKPASYGHYVYPMWADAV-GW 554 +L+ I + G+ YP+W AV GW Sbjct: 462 MLIQRIIVL--VTEGYEGYPLWYLAVAGW 488 Score = 89.8 bits (213), Expect = 2e-16 Identities = 42/117 (35%), Positives = 62/117 (52%), Gaps = 4/117 (3%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 R WTG+ F N+WRFP + Y NGGGAFLIP+ + LV AG+P++F++ + Sbjct: 18 REQWTGQLGFILSAIGSAVGLGNIWRFPGVAYENGGGAFLIPYLIALVTAGIPILFLDYA 77 Query: 86 FG-QYAALGPVA---VYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSF 138 G ++ P A + K LG+ V + I+ +YY ++AW Y T SF Sbjct: 78 IGHRFRGSSPTAFRRLGGKAGKWLESLGWFQVWICIIIAVYYAAVVAWAASYFTFSF 134 >UniRef50_O88575 Cluster: Sodium- and chloride-dependent transporter XTRP3; n=15; Euteleostomi|Rep: Sodium- and chloride-dependent transporter XTRP3 - Mus musculus (Mouse) Length = 635 Score = 155 bits (376), Expect = 3e-36 Identities = 73/175 (41%), Positives = 109/175 (62%) Query: 187 VSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCK 246 ++ N T + + + ++ + L +S I+E G ++ A+CL AW++V+LC+ + Sbjct: 171 LNSNHTGYDEECEKASSTQYFWYRKTLNISPSIQENGGVQWEPALCLTLAWLMVYLCILR 230 Query: 247 GVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQ 306 G +S+GKVVYFT PY VL+I RG+TL GA G+ + TP QLAN + W +AA Q Sbjct: 231 GTESTGKVVYFTTSLPYFVLIIYLVRGLTLHGATNGLAYMFTPKIEQLANPKAWINAATQ 290 Query: 307 IFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLA 361 IFF+L GGLI +SYN+ SN+C +LIV+V N T+ F+ +V FS+ GF A Sbjct: 291 IFFSLGLGCGGLIAFASYNEPSNDCQKHALIVSVINSTTAIFSSIVTFSIYGFKA 345 Score = 116 bits (279), Expect = 2e-24 Identities = 58/171 (33%), Positives = 88/171 (51%), Gaps = 10/171 (5%) Query: 22 IEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMF 81 +E R W F NVWRFPYLC GGG+FL+P+ +ML++ G+PL++ Sbjct: 44 VEKVRPKWDNPLQFLLVCISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLY 103 Query: 82 MELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSI 141 +EL+ GQ G + + P G+G ++VS + +Y+N+I W ++Y+ SF Sbjct: 104 LELAVGQRMRQGSIGAWRTISPYLSGVGIASLVVSFLASVYFNVINTWALWYLFHSFQD- 162 Query: 142 FYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYL--RQCFNQSYSVSHN 190 LPW C ++ H Y+E ECE + T Y R+ N S S+ N Sbjct: 163 --PLPWSVCPL--NSNHT-GYDE--ECEKASSTQYFWYRKTLNISPSIQEN 206 Score = 116 bits (278), Expect = 3e-24 Identities = 59/178 (33%), Positives = 96/178 (53%), Gaps = 7/178 (3%) Query: 362 HELNVSVDRVVD---QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMET 418 H N S++ +D QG GLAFIVY E + + +S LWS+L+F MLLTLG+ S Sbjct: 397 HIRNCSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLTLGMGSMVGTGTA 456 Query: 419 VTTAILD-RFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIA 477 + T + D + + K + +V + G++FT +G YW L + Y A S+L+I Sbjct: 457 ILTPLTDSKIISSYLPKEAISGLVCLLNCAIGMVFTMEAGNYWFDLFNDYTATLSLLLIV 516 Query: 478 IGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEY 535 + E I + ++YG ++F D++ M GR + W MW ++P +V + +F +Y Sbjct: 517 LVETIAVCYVYGLKRFESDLRAMTGRTLS---WYWKVMWAFVSPLLIVGLFIFYLSDY 571 >UniRef50_Q8BPL9 Cluster: 0 day neonate eyeball cDNA, RIKEN full-length enriched library, clone:E130309B01 product:gamma-aminobutyric acid (GABA-A) transporter 1, full insert sequence; n=15; Gnathostomata|Rep: 0 day neonate eyeball cDNA, RIKEN full-length enriched library, clone:E130309B01 product:gamma-aminobutyric acid (GABA-A) transporter 1, full insert sequence - Mus musculus (Mouse) Length = 256 Score = 154 bits (373), Expect = 8e-36 Identities = 83/231 (35%), Positives = 129/231 (55%), Gaps = 33/231 (14%) Query: 24 PERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFME 83 P+R W GRFDF NVWRFPYLC NGGGAFLIP+ + L+ AG+PL +E Sbjct: 42 PDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLE 101 Query: 84 LSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFY 143 S GQY ++G + V+ K P+F+G+G ++S + +YY +II+W I+Y+ SF++ Sbjct: 102 CSLGQYTSIGGLGVW-KLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTT-- 158 Query: 144 QLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPP 203 LPW+ C W+T +CF+ +YS+ N T + + Sbjct: 159 -LPWKQCDNPWNTD---------------------RCFS-NYSLV-NTTNMTSAVV---- 190 Query: 204 AEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKV 254 E++ + ++ G+++ G+IR +A+ L AWV+V+ C+ KGV +GKV Sbjct: 191 --EFWERNMHQMTDGLDKPGQIRWPLAITLAIAWVLVYFCIWKGVGWTGKV 239 >UniRef50_Q9CMU0 Cluster: Transporter; n=3; Pasteurellaceae|Rep: Transporter - Pasteurella multocida Length = 502 Score = 154 bits (373), Expect = 8e-36 Identities = 102/351 (29%), Positives = 170/351 (48%), Gaps = 11/351 (3%) Query: 207 YFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSS-GKVVYFTALFPYVV 265 +F + L ++ G+ + + L+ W+ + + L GVQ GK F V+ Sbjct: 131 FFFKEYLQMAEGVAVNFDFVASITGPLVGVWIFILVILALGVQKGIGKSATFFMPLLTVM 190 Query: 266 LVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYN 325 VIL + LPG+ G+ TPD+S+L VW A QIFF+LS +G +IT SSY Sbjct: 191 FVILVITALFLPGSAKGLNALFTPDWSKLLEPTVWVAAYGQIFFSLSICFGIMITYSSYL 250 Query: 326 KFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPE 385 K ++ L+V +N + AG+ +F+ +GF+A V V G GLAFI +P Sbjct: 251 KKQSDLTGSGLVVGFANSSFELLAGIGVFAALGFMATAAGKEVSEVATSGIGLAFIAFPA 310 Query: 386 VVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAV-F 444 ++ + P + +LFF LL G+ S +++E + A+ D+ R ++ + V Sbjct: 311 IIDQAPFGSVIGVLFFGSLLFAGITSLMSILEVIIAAVQDK---LRMRRSVATALTCVPM 367 Query: 445 GYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQ 504 + L+F T +G+ L ++DK+ ++ I+A+G ++ A + E G + Sbjct: 368 AIVSVLLFGTTTGLPVLDVLDKFVNSFG--IVAVGLMVIYAVLIN-ESLSGLAAHLNETS 424 Query: 505 SKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMW-ADAVGW 554 S +W + IT LV++L F I K A+ G+ YP W + GW Sbjct: 425 SFKVGVVWRVLIGTITSTVLVYML-FTEIN-KVATEGYGGYPAWFVNTFGW 473 Score = 93.5 bits (222), Expect = 2e-17 Identities = 41/115 (35%), Positives = 62/115 (53%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 R ++GR F N+WRFPY+ Y NGGGAF+IP+ V L+ AG+PL+F++ + Sbjct: 8 RETFSGRKAFIFAAIGSAVGLGNIWRFPYVTYENGGGAFIIPYLVALLTAGIPLLFLDYA 67 Query: 86 FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSS 140 G P + K F G+ V+++ I+ +YY +II W Y S +S Sbjct: 68 IGHKYRASPPLAFRKLNKNFETFGWWQVLINVIIGIYYAVIIGWAASYTYFSLNS 122 >UniRef50_UPI0001554745 Cluster: PREDICTED: similar to glycine transporter 2a; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to glycine transporter 2a - Ornithorhynchus anatinus Length = 670 Score = 150 bits (363), Expect = 1e-34 Identities = 64/134 (47%), Positives = 90/134 (67%), Gaps = 4/134 (2%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 RGNW+ + DF NVWRFPYL + NGGGAFLIP+ +ML +AGLP+ F+E+S Sbjct: 325 RGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVS 384 Query: 86 FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQL 145 GQ+A+ GPV+V+ K P +G G M+I+S ++ +YYN+II +T+FY+ SF S+ L Sbjct: 385 LGQFASQGPVSVW-KAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSV---L 440 Query: 146 PWQNCKAEWSTKHC 159 PW +C W+T C Sbjct: 441 PWASCNNPWNTPDC 454 Score = 72.5 bits (170), Expect = 3e-11 Identities = 38/158 (24%), Positives = 73/158 (46%), Gaps = 5/158 (3%) Query: 439 FIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQ 498 F + + L + FT + ++ ++Y + I + +++ G ++FC DI+ Sbjct: 480 FCMTAYPNLTLVNFTNQANKTFVSGSEEYFNLKQIFAIEMINTLVLNDTKGLQRFCEDIE 539 Query: 499 RMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGWTXXX 558 MIG Q ++ W W +TP L FIL F++ +++P +YG Y YP W+ +GW Sbjct: 540 MMIGFQPNIF---WKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLA 596 Query: 559 XXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWG 596 ++ P +E+ +++ P +WG Sbjct: 597 CSVIWIPIMFVIKMHLAPG--KFIERLKLVCSPQPDWG 632 >UniRef50_UPI00006611F1 Cluster: Homolog of Homo sapiens "Solute carrier family 6 (neurotransmitter transporter, dopamine), member 3; n=3; Takifugu rubripes|Rep: Homolog of Homo sapiens "Solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 - Takifugu rubripes Length = 376 Score = 147 bits (357), Expect = 7e-34 Identities = 89/244 (36%), Positives = 132/244 (54%), Gaps = 14/244 (5%) Query: 253 KVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALS 312 KV YFTA FPYV+L+IL RG+TLPGA GI FYL P L N ++W +A QIFF+ S Sbjct: 135 KVAYFTATFPYVMLLILLIRGLTLPGAFNGIYFYLYPSIEDLTNLKIWIEAGSQIFFSYS 194 Query: 313 PAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVV 372 G LI LSSYNK++NNCY D + + N TSF AG V+FS++GF+A + V+VD ++ Sbjct: 195 LVTGNLIVLSSYNKYNNNCYRDCFFLCLLNSCTSFLAGFVVFSILGFMAQQQGVTVDALI 254 Query: 373 DQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQ 432 D + F Y P L FV++ + G+D +++ +T A F F+ Sbjct: 255 DNYSASRFYDY----FMAPCECLVISWIFVIIFS-GVDRFMEIIKDMTGA--KPFIIFKL 307 Query: 433 KKGWVVFIVAVFGYLGGLI-FTTNSGMYWLQLMD-KYAANW-----SVLIIAIGECILIA 485 +++ +V++ + +I F W D YA W +V+++ + I + Sbjct: 308 LWKYIIPLVSLISLILFIINFKQLKINDWYVYPDWAYALGWMMTISTVIMVPLWAIIQMC 367 Query: 486 WIYG 489 W G Sbjct: 368 WTAG 371 Score = 87.0 bits (206), Expect = 1e-15 Identities = 36/82 (43%), Positives = 48/82 (58%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 RG W + ++ NVWRFPYLCY GGGAFLIP+ ++ V+ G+PL +E S Sbjct: 15 RGQWASKTEYILVIAGNVVGLGNVWRFPYLCYRYGGGAFLIPYCLLAVVFGVPLFLLETS 74 Query: 86 FGQYAALGPVAVYNKFCPLFRG 107 GQ+ G V + K CPL +G Sbjct: 75 LGQFTQEGFVTCWRKVCPLAQG 96 Score = 49.2 bits (112), Expect = 3e-04 Identities = 35/119 (29%), Positives = 58/119 (48%), Gaps = 12/119 (10%) Query: 443 VFGYLGGLIFTTNSGMYWLQLMDKYAAN-WSVLIIAIGECILIAWIY-----GAEKFCGD 496 VF LG G+ L+D Y+A+ + +A EC++I+WI+ G ++F Sbjct: 235 VFSILG--FMAQQQGVTVDALIDNYSASRFYDYFMAPCECLVISWIFVIIFSGVDRFMEI 292 Query: 497 IQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGH-YVYPMWADAVGW 554 I+ M G + + ++ +W+ I P + L+ I +K YVYP WA A+GW Sbjct: 293 IKDMTGAKPFI---IFKLLWKYIIPLVSLISLILFIINFKQLKINDWYVYPDWAYALGW 348 >UniRef50_UPI00015B5C87 Cluster: PREDICTED: similar to GA18750-PA; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to GA18750-PA - Nasonia vitripennis Length = 718 Score = 147 bits (355), Expect = 1e-33 Identities = 67/155 (43%), Positives = 98/155 (63%) Query: 207 YFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVL 266 ++ L + I++ ++ + +CLL +W +VF + KG+QSSGKVVYFT+LFPY+VL Sbjct: 214 FWYRTTLDAAPSIDDGQGLKWWIVLCLLLSWFVVFCIMMKGIQSSGKVVYFTSLFPYLVL 273 Query: 267 VILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNK 326 I F RG+TL GA G+ TP +L VW DAA Q+F++ A+G LI SYN Sbjct: 274 TIFFIRGITLKGADAGLAHMYTPKVEKLLEPTVWLDAATQVFYSFGLAFGSLIAFGSYNT 333 Query: 327 FSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLA 361 NNC D ++V+V N T+ +A +VIF+++GF A Sbjct: 334 PENNCVRDVILVSVCNAFTAIYASVVIFAILGFKA 368 Score = 124 bits (298), Expect = 1e-26 Identities = 56/156 (35%), Positives = 94/156 (60%), Gaps = 3/156 (1%) Query: 374 QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK 433 +G GLAFIV+ + + LP +P WS +FF+MLL LGL SQ L+E + + + R K Sbjct: 428 EGTGLAFIVFTQAIVELPGAPFWSCIFFLMLLALGLGSQIGLLEGMLCVVFEIDLFKRIK 487 Query: 434 KGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKF 493 K ++ ++ +F + GLIF T +G YWL++ D +A ++++A+ E + + ++YG +KF Sbjct: 488 KQYITGVLCLFCFFVGLIFCTGAGEYWLKMFDSFAGTIGLVLVALMEMLAVVYVYGHKKF 547 Query: 494 CGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILV 529 DI+ M G + L+ W W+ + P +V IL+ Sbjct: 548 TQDIEDMTGYRPGLY---WQITWKYLAPVIMVAILI 580 Score = 120 bits (288), Expect = 2e-25 Identities = 57/136 (41%), Positives = 76/136 (55%), Gaps = 6/136 (4%) Query: 18 LSEEIEPERGN---WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVI 74 L ++ EP++ N W+G+ F N+WRFPYLC NGGGAFLIPF VML++ Sbjct: 62 LQQQPEPKQENRAEWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFLIPFFVMLIL 121 Query: 75 AGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYM 134 G+PL +EL GQ G + V+N P G+G IV+ V LYYN+II W +Y+ Sbjct: 122 EGVPLFLIELGLGQRMRQGALGVWNTIHPWLGGIGIASCIVTFFVTLYYNVIITWCFYYL 181 Query: 135 TVSFSSIFYQLPWQNC 150 F+S L W C Sbjct: 182 ---FNSFREPLLWSEC 194 >UniRef50_A4R7E6 Cluster: Transporter; n=1; Magnaporthe grisea|Rep: Transporter - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 635 Score = 146 bits (353), Expect = 2e-33 Identities = 78/262 (29%), Positives = 139/262 (53%), Gaps = 4/262 (1%) Query: 237 WVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTP-DFSQLA 295 W +V+LC+ GV +G+VVYFT P V+++IL RG ++ A+ GI Y+ +L Sbjct: 126 WFVVWLCMFSGVGMTGRVVYFTMGMPIVMIIILLGRGASMENAVEGIKLYVAEWHGDKLG 185 Query: 296 NAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFS 355 +W AA IFF++ G + +SYN+ +N D+LI+A SN A AG +F Sbjct: 186 RPAIWQAAASHIFFSIGAGMGYYTSYASYNQKFSNAVQDALIIACSNSAIEVSAGFAVFG 245 Query: 356 VIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFAL 415 ++G+L + V+ LAFI P ++P S W+++FF+ ++ LG S FA+ Sbjct: 246 IVGYLG--IRPDSGEVLGT-YNLAFITLPAAFVQMPGSNFWAVIFFITIMVLGFSSCFAM 302 Query: 416 METVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLI 475 +E++ T ++D + R + V ++ + +L L++ T+ G L +D + ++ S++ Sbjct: 303 LESLVTLVMDTGISKRVSRVAVSTVIIIVSFLLSLMYCTHFGRDLLNAVDAWISDLSLVG 362 Query: 476 IAIGECILIAWIYGAEKFCGDI 497 I E ++ +Y G + Sbjct: 363 IVALESVVSTTVYRFRDVTGQV 384 Score = 44.4 bits (100), Expect = 0.009 Identities = 23/74 (31%), Positives = 39/74 (52%), Gaps = 3/74 (4%) Query: 74 IAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFY 133 + +P++ +E++ GQ G + Y+ +GLG +V+ IV Y+ I+AW + Y Sbjct: 5 LLAIPVVILEVAIGQAYRGGCLVAYDHISRRTKGLGLALVMNGYIVCNYFVPILAWVMIY 64 Query: 134 MTVSFSSIFYQLPW 147 SFS+ LPW Sbjct: 65 FRHSFSN---PLPW 75 >UniRef50_UPI000023D6A8 Cluster: hypothetical protein FG04240.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG04240.1 - Gibberella zeae PH-1 Length = 680 Score = 145 bits (351), Expect = 4e-33 Identities = 82/263 (31%), Positives = 137/263 (52%), Gaps = 8/263 (3%) Query: 237 WVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTP-DFSQLA 295 W +V++ + +G+ +G+VVYFT P ++ +IL R V+LP A GI Y + +LA Sbjct: 194 WFLVWVSIFRGIGQTGRVVYFTMSLPVILTIILVGRSVSLPNAGRGIKLYFGEWNGDKLA 253 Query: 296 NAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFS 355 + ++W AA Q+FF+ +G + +SYN+ +N +DS ++ SN+ FA F Sbjct: 254 SGEIWQTAAGQVFFSTGVGFGYFSSYASYNQKHSNAVMDSCLIVGSNVIFEGFAAFAAFG 313 Query: 356 VIGFLAHELNVSVDRVVDQGA-GLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFA 414 V+GFL V +R+ GA + F+ P +T+LP S W+ F L+ LG S FA Sbjct: 314 VVGFLG-MAPVENERI---GAFTIGFLTLPTAITQLPGSSFWAFALFFTLVVLGYSSAFA 369 Query: 415 LMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVL 474 +++ V T I+D P R++ WVV + V +L L + T G L +D++ + +++ Sbjct: 370 MLDAVVTLIMDTKPRIRRE--WVVTGLVVVSFLISLPYCTQFGYALLTGVDRWINDVALV 427 Query: 475 IIAIGECILIAWIYGAEKFCGDI 497 + EC Y G + Sbjct: 428 FVVFSECAFSTTFYRWRDVAGQV 450 Score = 72.5 bits (170), Expect = 3e-11 Identities = 35/139 (25%), Positives = 65/139 (46%), Gaps = 3/139 (2%) Query: 16 APLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIA 75 +P + + R +W R F N+ R+P YNN G + IP+ + + + Sbjct: 15 SPPPSKAQDGRESWNSRASFLLAAMGGCAGMGNLIRYPSQVYNNNGLQWFIPYLMCVFLI 74 Query: 76 GLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMT 135 +P + +E+S GQ G V +N +G+G+ ++ + +V Y+ + ++W + Y Sbjct: 75 AIPALILEVSIGQAYRGGSVVAFNNINHRLKGMGFSLLYIGFMVTPYFVVNLSWIMIYFR 134 Query: 136 VSFSSIFYQLPWQNCKAEW 154 SF S LPW+ E+ Sbjct: 135 NSFQS---PLPWEGRAEEY 150 >UniRef50_A5UNF8 Cluster: Na+-dependent transporter, SNF family; n=2; Methanobrevibacter smithii ATCC 35061|Rep: Na+-dependent transporter, SNF family - Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM 861) Length = 498 Score = 144 bits (350), Expect = 5e-33 Identities = 100/332 (30%), Positives = 165/332 (49%), Gaps = 17/332 (5%) Query: 207 YFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLC----LCKGVQSSGKVVYFTALFP 262 YFT L + + G +A+ +L WVI+++ L KG+ KV+ LF Sbjct: 130 YFTGSFLQANDTLGGLGTFVPFVAIAMLVGWVIMWVISHTDLEKGLGRVSKVLV-PLLFA 188 Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322 ++ ++LF +TLPGA G+ PD+S L N +W A Q+ F+LS T + Sbjct: 189 IMIFIVLF--SLTLPGAGIGLAELYNPDWSLLLNFNIWMAAFGQMIFSLSLGMSIAFTYA 246 Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIV 382 SY K ++ ++L V V+N FA + +FS++G+++ + V+V +V QG GL FIV Sbjct: 247 SYTKDDSDLVSNALWVTVANCGFENFAAIGVFSILGYMSLQSGVAVPDLVTQGTGLVFIV 306 Query: 383 YPEVVTRL-PISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIV 441 YP V L + + LFF + GL S + +E ++ +I ++F R K + I+ Sbjct: 307 YPTVFNVLGDWASVIGPLFFFTVYLAGLTSILSTIEPLSFSIQNKFGWSRNK---TMTIL 363 Query: 442 AVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMI 501 VFG +I+ T G Y L + D + ++LI I ECI+ AWI+ AE I ++ Sbjct: 364 CVFGAAVSMIYATAMGSYILGIADTFVNQIAILIGVIFECIIFAWIFKAENI---IPKLN 420 Query: 502 GRQSKLWVYLWSAMWRIITPAALVFILVFNWI 533 + + + W W ++ L + W+ Sbjct: 421 AKSKSIKLGKW---WLVVVKYVLPIFIAIVWV 449 Score = 80.2 bits (189), Expect = 2e-13 Identities = 34/114 (29%), Positives = 60/114 (52%), Gaps = 2/114 (1%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 ++ W F N+WR+PY+ Y+NGGGAF IP+ V ++I G+P + +E Sbjct: 6 DKNEWGSNLSFLLAMIGSAVGLGNIWRYPYVLYSNGGGAFFIPYIVAILIMGIPFLILEY 65 Query: 85 SFG-QYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVS 137 G + + P AV + LG+ + + ++++YY+ I+ W FY+ +S Sbjct: 66 GVGYNFKSSFPKAV-KSISKKWEYLGWFLPVAVFMILIYYSAILGWDGFYVIIS 118 >UniRef50_Q2NGG4 Cluster: Predicted Na+-dependent transporter; n=1; Methanosphaera stadtmanae DSM 3091|Rep: Predicted Na+-dependent transporter - Methanosphaera stadtmanae (strain DSM 3091) Length = 491 Score = 144 bits (349), Expect = 6e-33 Identities = 94/314 (29%), Positives = 168/314 (53%), Gaps = 19/314 (6%) Query: 208 FTNQVLGLSSGIEETG--EIRLGMAMCLLAAWVIVFLC----LCKGVQSSGKVVYFTALF 261 F N V+ L S + +G I + + + L W+I++ + KG+ K++ T L Sbjct: 130 FLNTVI-LESTTDVSGLFHIAIYVLIALTIVWIILWYISHHDINKGIGKFNKIL--TPLL 186 Query: 262 PYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITL 321 +++++I+ +TLPG+ G+L LTPD S + N+ +W A QI F+LS ++ Sbjct: 187 -FIIMIIIVAFALTLPGSGFGVLTLLTPDLSAITNSDIWIAALSQILFSLSIGMCIVVAY 245 Query: 322 SSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFI 381 ++Y N + L+VA++N + F + IF ++GF++ + ++ +V QG LAF+ Sbjct: 246 TAYLPDDVNIPKNVLLVALANSSFEVFTAIGIFGILGFMSTTHGIPINELVTQGTTLAFV 305 Query: 382 VYPEVVTRLP-ISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFI 440 +P++ + I + LFF+ LL G+ S ++ME + ++ D+F F +KK V I Sbjct: 306 AFPQIFNVMGFIGYIIGPLFFIALLFAGITSNISIMEPIILSLRDKF-GFERKK--AVTI 362 Query: 441 VAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQR- 499 V G++ L+FTT+ G + + D + + V++ I E ILI WIYG +K I + Sbjct: 363 CCVVGFIISLLFTTSLGSSLVGVFDTFINQFGVVLNVIIELILITWIYGIDKILPGINKN 422 Query: 500 ----MIGRQSKLWV 509 IG + K+W+ Sbjct: 423 ATFLKIGPKWKIWM 436 Score = 83.0 bits (196), Expect = 2e-14 Identities = 31/110 (28%), Positives = 56/110 (50%) Query: 29 WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQ 88 W F N+WR+PY+ Y NGGGAF++P+ + ++ G+PL+F+E G Sbjct: 10 WESNISFILAMIGSAVGLGNIWRYPYVAYTNGGGAFILPYIISIICLGIPLLFIEYGTGY 69 Query: 89 YAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSF 138 G + K + +G+ + + ++ YY ++AW + Y+ +SF Sbjct: 70 KFKSGMSKILRKINTKYEYIGWFIQTSTFFILTYYVCVVAWNLLYVPLSF 119 >UniRef50_UPI0000DB790B Cluster: PREDICTED: similar to CG5549-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to CG5549-PA - Apis mellifera Length = 174 Score = 143 bits (347), Expect = 1e-32 Identities = 63/141 (44%), Positives = 88/141 (62%), Gaps = 3/141 (2%) Query: 21 EIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLM 80 E +PERG+W+ +F NVWRFPYL Y NGGGAF+IPF +ML+ GLP+ Sbjct: 26 EQDPERGSWSNPIEFVLSCIGYAVGIGNVWRFPYLVYRNGGGAFIIPFVLMLITMGLPIF 85 Query: 81 FMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSS 140 F+EL+ GQY+ LGP + + P GLGY +IV +VM+YY +I+AWT+FY +F S Sbjct: 86 FLELAVGQYSGLGPNEAFKRMAPALEGLGYCTLIVILLVMVYYMVIVAWTLFY---TFLS 142 Query: 141 IFYQLPWQNCKAEWSTKHCYS 161 +L W C +++T Y+ Sbjct: 143 FLPKLSWAYCDNDFNTNREYT 163 >UniRef50_P44849 Cluster: Uncharacterized sodium-dependent transporter HI0736; n=30; Bacteria|Rep: Uncharacterized sodium-dependent transporter HI0736 - Haemophilus influenzae Length = 508 Score = 143 bits (346), Expect = 1e-32 Identities = 97/326 (29%), Positives = 159/326 (48%), Gaps = 14/326 (4%) Query: 233 LLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLV--ILFFRGVTLPGAITGILFYLTPD 290 L+A W++ L GVQ G + L P +V++ +L + LPGA G+ TPD Sbjct: 161 LIAMWIVALGVLSMGVQK-GIAKVSSVLMPVLVVMFMVLVIYSLFLPGAAKGLDALFTPD 219 Query: 291 FSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAG 350 +S+L+N VW A QIFF+LS +G ++T +SY K ++ L+V +N + AG Sbjct: 220 WSKLSNPSVWIAAYGQIFFSLSIGFGIMVTYASYLKKESDLTGSGLVVGFANSSFEVLAG 279 Query: 351 LVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLD 410 + +F+ +GF+A V V G GLAF +P ++ + P + +LFF L L Sbjct: 280 IGVFAALGFIATAQGQEVSEVAKGGIGLAFFAFPTIINKAPFGEVLGMLFFGSLTFAALT 339 Query: 411 SQFALMETVTTAILDRFPNFRQKKGWVVFIVAV-FGYLGGLIFTTNSGMYWLQLMDKYAA 469 S +++E + +AI D+ R +G V FIV V + ++F T +G+ L + DK+ Sbjct: 340 SFISVIEVIISAIQDK---IRISRGKVTFIVGVPMMLVSVILFGTTTGLPMLDVFDKFVN 396 Query: 470 NWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILV 529 + ++ +A I I A + G + + S V + + ++T L F+L Sbjct: 397 YFGIVAVAFASLIAIV----ANEKLGLLGNHLNETSSFKVGFFWRLCIVLTSGVLAFMLF 452 Query: 530 FNWIEYKPASYGHYVYPMW-ADAVGW 554 K S G+ YP W + GW Sbjct: 453 SEGA--KVFSEGYEGYPNWFVNTFGW 476 Score = 96.3 bits (229), Expect = 2e-18 Identities = 42/122 (34%), Positives = 66/122 (54%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 +R ++GR F N+WRFPY Y NGGGAF+IP+ + L+ AG+PL+F++ Sbjct: 10 KRETFSGRRAFILAAIGSAVGLGNIWRFPYTTYENGGGAFIIPYLIALLTAGIPLLFLDY 69 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 + G G Y +F P F G+ ++V+ I+ LYY +++ W Y SF+ + Sbjct: 70 AIGHRHRGGAPLSYRRFSPHFEVFGWWQMMVNVIIGLYYAVVLGWAASYTYFSFTGAWGD 129 Query: 145 LP 146 P Sbjct: 130 KP 131 >UniRef50_A7BDH7 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 528 Score = 141 bits (342), Expect = 4e-32 Identities = 94/317 (29%), Positives = 166/317 (52%), Gaps = 14/317 (4%) Query: 233 LLAAWVIVFLC----LCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLT 288 L WV+V L KGV+++ KV + ++ LV+ R + LPGA+ G+ + T Sbjct: 162 LALVWVLVLFVIGRGLSKGVEAANKVFLPLLVILFLALVV---RALFLPGAVEGLNAFFT 218 Query: 289 PDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFF 348 P++S LA+ VW A QIF++LS +G ++T +SY K +N +L+ +N + Sbjct: 219 PNWSALADPNVWLAAFAQIFYSLSVGFGIMLTYASYLKPKSNLTGTALVAGFANSSFEIL 278 Query: 349 AGLVIFSVIGFLAHELNVSVDRVVD-QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTL 407 AG+ +FS IGF+AH+ VSV V G L+F+ +P++++ +P PL+ +LFF L+ Sbjct: 279 AGIGVFSAIGFMAHQGGVSVSEVEGLTGPILSFVTFPKIISMMPGGPLFGVLFFSSLVLA 338 Query: 408 GLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKY 467 G+ S +L++ V+ + D+F + V+ + A + ++F T SG+ L ++D + Sbjct: 339 GVTSLLSLLQVVSGGLQDKFGWSPARSALVLGVPAT--VISLVLFGTRSGLNNLDIVDNF 396 Query: 468 AANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWV-YLWSAMWRIITPAALVF 526 + V+ AI +L A + G G ++ I S + V LW + I+ P L Sbjct: 397 INSVGVVSSAIMFAVLCA-VAGPR--LGVLRAHINSVSSVKVPKLWEPLVGIVIPVVLFV 453 Query: 527 ILVFNWIEYKPASYGHY 543 ++ + ++ Y Y Sbjct: 454 MMAMSIVQVLKQGYESY 470 Score = 82.2 bits (194), Expect = 4e-14 Identities = 35/112 (31%), Positives = 58/112 (51%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 R +W+G+ F N+WRFP + Y+NGGGAFL+P+ V LV G+P+++++ + Sbjct: 13 RDSWSGQTGFLLAAIGSAIGLGNIWRFPGVSYSNGGGAFLVPYLVALVFVGIPMLWLDYA 72 Query: 86 FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVS 137 G P K +G+ V ++M+YY ++AW + Y S Sbjct: 73 VGHKFRGSPPWALRKIIGGGEFVGWFQTFVCFVIMVYYGAVLAWGVQYTIYS 124 >UniRef50_UPI0001556266 Cluster: PREDICTED: similar to Solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12, partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to Solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12, partial - Ornithorhynchus anatinus Length = 219 Score = 140 bits (340), Expect = 8e-32 Identities = 63/120 (52%), Positives = 83/120 (69%) Query: 254 VVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSP 313 VVYFTA FPY++L+IL RGVTLPGA GI++YL PD +LA+ QVW DA QIFF+ + Sbjct: 1 VVYFTATFPYLMLIILLVRGVTLPGASQGIVYYLKPDVQRLADPQVWMDAGTQIFFSFAI 60 Query: 314 AWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVD 373 G L L SYNK+ NNCY D + + + N +TSF AG +FS++GF+A E V + V + Sbjct: 61 CQGCLTALGSYNKYHNNCYRDCIALCILNSSTSFVAGFAVFSILGFMAQEQGVPISEVAE 120 >UniRef50_Q0PHT6 Cluster: High-affinity dopamine transporter protein; n=2; Arthropoda|Rep: High-affinity dopamine transporter protein - Limulus polyphemus (Atlantic horseshoe crab) Length = 250 Score = 138 bits (333), Expect = 5e-31 Identities = 63/152 (41%), Positives = 89/152 (58%), Gaps = 5/152 (3%) Query: 51 RFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGY 110 RFPYLCY NGGGAFL+P+ +ML + G+PL +MEL+ GQY G + + + PL +G+GY Sbjct: 1 RFPYLCYKNGGGAFLVPYLIMLAVGGIPLFYMELALGQYHRQGAITCWGRLVPLLKGVGY 60 Query: 111 GMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEA 170 +++++ V YYN+IIAW + Y SF+S +LPW C W+T C + E E Sbjct: 61 AVILIAFYVDFYYNVIIAWALHYFFASFTS---ELPWTRCNNTWNTPECVGLAISKESEF 117 Query: 171 QNGTYYLRQCFNQSYSVSHNITALAKTALRRP 202 N L FN S V +T K ++R P Sbjct: 118 SNNETSL-DWFNFS-EVITEVTNWTKNSIRTP 147 Score = 46.0 bits (104), Expect = 0.003 Identities = 25/70 (35%), Positives = 38/70 (54%), Gaps = 2/70 (2%) Query: 185 YSVSHNITALAKTALRRPPAEEYFTNQVLGL--SSGIEETGEIRLGMAMCLLAAWVIVFL 242 ++ + + L K A EYF +L L S GIE G ++ MA+CLLA ++I + Sbjct: 181 FNNTDTVAILRKRNQGASSAAEYFNRGLLELHKSGGIENLGIVKWDMALCLLAVYLICYF 240 Query: 243 CLCKGVQSSG 252 L KG+ +SG Sbjct: 241 SLWKGISTSG 250 >UniRef50_Q0PHU0 Cluster: High-affinity dopamine transporter protein; n=4; Mandibulata|Rep: High-affinity dopamine transporter protein - Spirostreptus sp. CD-2006 Length = 224 Score = 137 bits (332), Expect = 7e-31 Identities = 84/227 (37%), Positives = 118/227 (51%), Gaps = 28/227 (12%) Query: 51 RFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGY 110 RFPYLCY NGGGAFLIP+ +ML I G+PL +MEL+ GQY G + + + PLF+G+GY Sbjct: 1 RFPYLCYKNGGGAFLIPYIIMLCIGGIPLFYMELALGQYHRKGAITCWGRLVPLFKGIGY 60 Query: 111 GMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIF----YQLPWQ--NCK------------- 151 +V+++ V YYN+IIAW + Y SF+S PW +C+ Sbjct: 61 AVVLIAFYVDFYYNVIIAWALHYFFASFASELPWTKCNNPWNTPDCQEIGSSPLQPPRND 120 Query: 152 --AEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRP--PAEEY 207 + WST S E + T+ N T + + L R PA EY Sbjct: 121 AISNWSTPWSPSSESFLDYA---WTFTESTLDGVDIRQDTNATTVLEMDLTRKSSPAAEY 177 Query: 208 FTNQVLGL--SSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSG 252 F L L SSGI + G ++ MA+CLLA ++I + + KG+ +SG Sbjct: 178 FNRAFLELHKSSGIGDLGYVKWDMALCLLAVYLICYFSMWKGISTSG 224 >UniRef50_Q2NGB7 Cluster: Predicted Na+-dependent transporter; n=2; Methanobacteriaceae|Rep: Predicted Na+-dependent transporter - Methanosphaera stadtmanae (strain DSM 3091) Length = 497 Score = 136 bits (329), Expect = 2e-30 Identities = 74/279 (26%), Positives = 147/279 (52%), Gaps = 8/279 (2%) Query: 237 WVIVFLCLCKGVQSS-GKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLA 295 W+ ++L K +++ GKVV T ++ ++ TL G + G+ PD+S L Sbjct: 168 WIFLWLVSRKNIENGIGKVVKITIPSLICIMFLIVAYSFTLNGHMIGLTNLFNPDWSALL 227 Query: 296 NAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDS-LIVAVSNIATSFFAGLVIF 354 N+ +W A Q+ F+LS +T +SY +N+ +DS L+VA SN + + +F Sbjct: 228 NSDIWLAAFTQVLFSLSVGQSIALTYASYLD-NNDHLVDSVLVVAASNSSFEIITAIGVF 286 Query: 355 SVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRL-PISPLWSILFFVMLLTLGLDSQF 413 +++GF++ + + ++++ G GL F+V+PE+ + ++ + FF+ + G+ + F Sbjct: 287 NILGFMSLKTGLGIEQIATSGTGLIFVVFPEIFNIMGDVAYIIGPAFFLCVFFAGVTTMF 346 Query: 414 ALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSV 473 A +E ++ ++ +F R K IV FG+L +IFTT +G Y L + D++ + + Sbjct: 347 AFIEPMSLSLAKKFKMSRSK---TATIVCFFGFLTSIIFTTGAGNYILAIADEFINQYGI 403 Query: 474 LIIAIGECILIAWIYGAEKFCGDI-QRMIGRQSKLWVYL 511 L + + I+ W+YG +K + ++ I W+++ Sbjct: 404 LFAILLQAIIFGWLYGIDKLVPILNEKSIVHIGSKWIWI 442 Score = 78.2 bits (184), Expect = 6e-13 Identities = 33/115 (28%), Positives = 55/115 (47%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 E W F N+WRF Y+ Y+NGGG+F IP+ ++ G+P + +E Sbjct: 14 EAYKWGSNISFLFAMIGAAIGLGNIWRFSYIVYSNGGGSFFIPYIFAILTLGVPFLILEY 73 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFS 139 G ++ P F +G+ +V + +VM YY +II W + Y+ + F+ Sbjct: 74 GLGVKHRDSLSSILKNLNPKFEVIGWFIVFLVFLVMTYYIVIIGWDVIYLLLGFT 128 >UniRef50_A7RHB6 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 318 Score = 135 bits (326), Expect = 4e-30 Identities = 90/318 (28%), Positives = 153/318 (48%), Gaps = 36/318 (11%) Query: 48 NVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQ-YAALGPVAVYNKFCPLFR 106 NV RF LC+ +GG AF IP+ +ML++ G PL+ +E++ GQ + V + P Sbjct: 28 NVVRFSQLCHKHGGVAFFIPYILMLMLEGTPLLCLEMAVGQRFGKKSLVQAWGDLKPNLS 87 Query: 107 GLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEAD 166 GLG +I ++IV+ YYN+++ W ++Y S L W+ C S + + + + Sbjct: 88 GLGLAAIIENTIVLFYYNVLVTWCLYYFVQSLRG---TLIWEPCGITSSVQGNQTSQIVE 144 Query: 167 -ECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEI 225 EC Y + +S ++S +I + SSG + Sbjct: 145 TECAKAGAEKYF--WYRKSLNISDDINS----------------------SSG------V 174 Query: 226 RLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGI-L 284 + M + + AW +L +G++ S K+++ + V VI FF V L G G+ L Sbjct: 175 NMFMYLFVFMAWTSAWLLSMRGIRRSSKLMWLILVLIVVEFVIFFFFAVDLKGWTYGLSL 234 Query: 285 FYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIA 344 + L + VW DAA QIF+++ +G I SS N NN + D+++ +++N Sbjct: 235 LFSFDRLDTLKSIDVWLDAAGQIFYSMGIGYGSNILFSSGNNHDNNLFSDAIVCSLANSG 294 Query: 345 TSFFAGLVIFSVIGFLAH 362 TS +A +++FS G+ AH Sbjct: 295 TSIWASIIMFSFFGYRAH 312 >UniRef50_UPI0000E816B2 Cluster: PREDICTED: similar to solute carrier family 6 (neurotransmitter transporter), member 17; n=1; Gallus gallus|Rep: PREDICTED: similar to solute carrier family 6 (neurotransmitter transporter), member 17 - Gallus gallus Length = 521 Score = 133 bits (322), Expect = 1e-29 Identities = 60/132 (45%), Positives = 77/132 (58%), Gaps = 4/132 (3%) Query: 20 EEIEPE-RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLP 78 EE++ E R W + + NVWRFPYLC NGGGA+L+P+ V+L+I GLP Sbjct: 53 EELDAENRPAWNSKLQYILAQIGYSVGLGNVWRFPYLCQKNGGGAYLVPYLVLLIIIGLP 112 Query: 79 LMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSF 138 L F+EL+ GQ G + V+N CP G+GY +V V LYYN+II W+IFY F Sbjct: 113 LFFLELAVGQRIRRGSIGVWNYICPRLGGIGYASCLVCFFVGLYYNVIIGWSIFYF---F 169 Query: 139 SSIFYQLPWQNC 150 S Y LPW C Sbjct: 170 KSFQYPLPWSEC 181 Score = 121 bits (292), Expect = 5e-26 Identities = 55/113 (48%), Positives = 78/113 (69%) Query: 253 KVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALS 312 +V+YF++LFPYVVLV RG+ L GA+ GI+ TP ++ + QVW +AA Q+FFAL Sbjct: 221 EVMYFSSLFPYVVLVCFLVRGLLLRGAVDGIMHMFTPKLDKMLDPQVWREAATQVFFALG 280 Query: 313 PAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELN 365 +GG+I SSYNK NNC+ D+ +V+ N TS A LV+F+V+GF A+ +N Sbjct: 281 LGFGGVIAFSSYNKQDNNCHFDATLVSFINFFTSVLATLVVFAVLGFKANIMN 333 Score = 107 bits (258), Expect = 7e-22 Identities = 55/139 (39%), Positives = 80/139 (57%), Gaps = 4/139 (2%) Query: 354 FSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQF 413 F +G A L +D+ V QG GLAFI + E +T P SP WS++FF+ML+ LGL S Sbjct: 387 FKELGLDACLLEDELDKSV-QGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMI 445 Query: 414 ALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSV 473 M +TT I+D F+ +K +F ++ GLIF SG Y++ + D Y+A + Sbjct: 446 GTMSGITTPIID---TFKVRKEVFTVGCCIFAFVVGLIFVQRSGNYFVTMFDDYSATLPL 502 Query: 474 LIIAIGECILIAWIYGAEK 492 ++ I E I +AWIYG +K Sbjct: 503 TVVVILENIAVAWIYGTKK 521 >UniRef50_Q0UQY0 Cluster: Transporter; n=1; Phaeosphaeria nodorum|Rep: Transporter - Phaeosphaeria nodorum (Septoria nodorum) Length = 681 Score = 133 bits (321), Expect = 2e-29 Identities = 81/271 (29%), Positives = 135/271 (49%), Gaps = 12/271 (4%) Query: 239 IVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGI-LFYLTPDFSQLANA 297 +V+LC+ +G +G+VVYFT P +V+VIL RG +LP A GI L++ T L+ Sbjct: 186 LVWLCIFRGTGWTGRVVYFTMGMPLIVIVILIGRGASLPNAGRGIRLYFATWRSEALSGT 245 Query: 298 QVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVI 357 +W DA Q+F++ +G +SYN N D++I+ +N F ++ Sbjct: 246 GIWQDAVGQVFYSTGVGFGFYTAYASYNHQFANAAQDAVILVFTNAFLEASLAFAAFGIV 305 Query: 358 GFLAHELNVSVDRVVDQGA-GLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALM 416 GF + ++ D G+ L F+ YPE +P S WS LFF+ L +G+ S F ++ Sbjct: 306 GF----MGMTPDPENPMGSYSLGFMTYPEAFVHMPGSNFWSALFFLTLAVVGVSSTFVML 361 Query: 417 ETVTTAILD-RFPNFRQ-KKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVL 474 + T I+D F R+ + WV ++ +L L T G Y+L +D++ N ++ Sbjct: 362 DAFMTLIMDSAFARTRRWTRTWVATVLVFVVFLLSLPNCTQFGYYYLDGIDRWINNVGLV 421 Query: 475 IIAIGECILIAWIYGAEKFCGDIQRMIGRQS 505 + EC+ +Y E D+ +G Q+ Sbjct: 422 FVVWAECVSATTVYRFE----DVVDQVGLQA 448 Score = 73.7 bits (173), Expect = 1e-11 Identities = 40/132 (30%), Positives = 61/132 (46%), Gaps = 3/132 (2%) Query: 16 APLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIA 75 AP ++ R W R F N R+P +NN G + IP+ + LV+ Sbjct: 12 APPPQKAADGRDQWPSRTAFILASLSGVIGMGNFLRYPSTVFNNHGLQWFIPYLLALVLL 71 Query: 76 GLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMT 135 +P + +EL+ G G V +NK RG G+ + V +V +Y+ IIAW + + Sbjct: 72 AVPALALELAAGNAYRGGTVTAFNKISRRMRGTGFALNYVGLVVSIYFIPIIAWGMVFFQ 131 Query: 136 VSFSSIFYQLPW 147 SF+S LPW Sbjct: 132 KSFTS---PLPW 140 >UniRef50_Q9VLY3 Cluster: Transporter; n=6; Drosophila melanogaster|Rep: Transporter - Drosophila melanogaster (Fruit fly) Length = 596 Score = 132 bits (319), Expect = 3e-29 Identities = 127/520 (24%), Positives = 234/520 (45%), Gaps = 35/520 (6%) Query: 17 PLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAG 76 P S ++ RG W DF +V+ + + + G ++P+ V + I Sbjct: 13 PFSPDLN--RGKWDKPTDFMFACFGLALKL-DVFVASFWMFFDMGILGILPYFVYMSIYL 69 Query: 77 LPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTV 136 +P+M + GQ+++ G ++ + + P F+G+GY ++ +++YY++ A + ++ Sbjct: 70 VPIMVIHSFMGQFSSSGFISAF-RLSPFFKGMGYVSGFLTISMLIYYSIFAAVPLLFIIN 128 Query: 137 SFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAK 196 SF LPW +C+ S+ H S + C N T L F++ Y+ SH + + Sbjct: 129 SFRPT---LPW-SCEG-LSSWHNGSATLSSSC---NKTLILED-FSE-YNRSHQLLHVPS 178 Query: 197 TALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSS--GKV 254 + Y + Q + ++ E+ WV++ K +++ GK+ Sbjct: 179 VLYFQ---NHYDSMQQDAVPDWYKDY-ELSWHFVGLFAIIWVVIAFIFYKFSETAKFGKL 234 Query: 255 VYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPA 314 + + + V+L++ F R + LPGA+ G+ Y+TP S +A V + + A Sbjct: 235 IRYMVIVTLVLLLVCFVRFLFLPGALNGLHRYVTPKASDMAMGVV--STFIMVLHAFGAG 292 Query: 315 WGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVS-VDRVVD 373 WG +ITLSS+N F + S I++ I G+V F L H N + + V D Sbjct: 293 WGSVITLSSFNGFKTDIMSYSWIISFGQIFIYIMFGMVSF----MLEHYFNGNKLSDVDD 348 Query: 374 QGAGLA-FIVY---PEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPN 429 G L+ +++Y ++ + LW+ +++ MLL L + TV ++ D F Sbjct: 349 NGHVLSHWLLYLSSASALSTMAWPNLWTFIYYSMLLIAALIVMTTQIFTVLQSLFDEFEV 408 Query: 430 FRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYG 489 R +K V F + L F TN G+ + + A +S ++ + +++ WIYG Sbjct: 409 LRVRKQEVTFGLIGGIALCSFYFCTNHGIIFFSALG-LDAIFSHSLLHLLLLLVVLWIYG 467 Query: 490 AEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILV 529 E+F DI+ M+G+ W + R I P LV L+ Sbjct: 468 RERFQRDIEFMLGQPFASWKVF---ILRFIAPIILVICLL 504 >UniRef50_A4RP68 Cluster: Transporter; n=2; Sordariomycetes|Rep: Transporter - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 668 Score = 131 bits (317), Expect = 5e-29 Identities = 80/253 (31%), Positives = 125/253 (49%), Gaps = 4/253 (1%) Query: 237 WVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQ-LA 295 W ++C KGV +G+V+Y T P +++VIL R ++LP A G YL S+ LA Sbjct: 198 WFASWICTFKGVGMTGRVIYVTMALPLIMIVILAVRSLSLPNASDGFRLYLGVWRSESLA 257 Query: 296 NAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFS 355 VW DA Q+FF++ +G + +SYN N DS I+A+SN A + L + Sbjct: 258 GPTVWQDAFGQMFFSIGVGFGYFTSYASYNSKFANAVQDSFIIALSNSAIEIVSALAVMG 317 Query: 356 VIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFAL 415 ++GFL + + R+ +G F YP + +P + +S LFF+ L+ LGL FAL Sbjct: 318 IVGFLGLDFETT-GRLGTFSSG--FFYYPRALVEMPGANFFSALFFLTLVCLGLTCVFAL 374 Query: 416 METVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLI 475 E + T I D R + V V + YL L++ T G L +D + + ++ Sbjct: 375 YEVLVTMICDSDWGKRVPRWAVSTTVIIASYLITLLYCTEVGFALLDAVDGFVNDLALFF 434 Query: 476 IAIGECILIAWIY 488 EC+ +Y Sbjct: 435 TVWCECMFATTLY 447 Score = 72.1 bits (169), Expect = 4e-11 Identities = 43/133 (32%), Positives = 63/133 (47%), Gaps = 3/133 (2%) Query: 16 APLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIA 75 AP +++ E R N+ R F N+ RFP + YNN G F IP+ L Sbjct: 24 APDAKKDEDGRDNFNSRSQFVLCAMGGAVGLGNLLRFPSVVYNNYGLQFFIPYLFALFCI 83 Query: 76 GLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMT 135 G+P++ +E+ GQ G V +N +G+G+ MV V YY I+A+ + Y Sbjct: 84 GIPILCLEICLGQAYRGGCVTAWNNNNHRAKGVGFSMVFNGYSVSGYYVAILAYAMSYFR 143 Query: 136 VSFSSIFYQLPWQ 148 SF + LPWQ Sbjct: 144 RSFEN---PLPWQ 153 >UniRef50_Q0G8L9 Cluster: High-affinity octopamine transporter protein; n=2; Pterygota|Rep: High-affinity octopamine transporter protein - Anax junius (common green darner) Length = 234 Score = 129 bits (312), Expect = 2e-28 Identities = 55/112 (49%), Positives = 77/112 (68%), Gaps = 3/112 (2%) Query: 51 RFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGY 110 RFPYLCY NGGGAFLIP+T+MLV LPL +MEL GQ+ GP++V+ + CPLF+G+G+ Sbjct: 1 RFPYLCYRNGGGAFLIPYTLMLVFGALPLFYMELILGQFNRQGPISVW-RICPLFKGVGF 59 Query: 111 GMVIVSSIVMLYYNLIIAWTIFYMTVSFSSI--FYQLPWQNCKAEWSTKHCY 160 V+V+ V YYN+II W ++++ S S+ LPW +C W+T C+ Sbjct: 60 CAVLVAFYVSFYYNVIIGWALYFLVASASAAPSSADLPWLHCNNSWNTDACW 111 Score = 41.1 bits (92), Expect = 0.087 Identities = 21/71 (29%), Positives = 38/71 (53%), Gaps = 2/71 (2%) Query: 184 SYSVSHNITALAKTALRRPPAEEYFTNQVLGL--SSGIEETGEIRLGMAMCLLAAWVIVF 241 +++ SH+ + PA EYF VL + S G+ + G + + +C+ + +++ Sbjct: 164 THAHSHHAPQAPQARPANSPASEYFHRAVLEMQGSGGLHDLGVPKWQLVLCVFLVYTMLY 223 Query: 242 LCLCKGVQSSG 252 L L KGV+SSG Sbjct: 224 LSLFKGVKSSG 234 >UniRef50_Q6F6P5 Cluster: Transporter; n=2; Acinetobacter|Rep: Transporter - Acinetobacter sp. (strain ADP1) Length = 492 Score = 128 bits (309), Expect = 4e-28 Identities = 87/289 (30%), Positives = 148/289 (51%), Gaps = 14/289 (4%) Query: 205 EEYFTNQVLGLS--SGIEETGEIRLGMAMCLLAAWVIVFLCLC----KGVQSSGKVVYFT 258 E +F N L S SG++ T L +L W + + L KGV+ S K+ F Sbjct: 126 EAFFFNTYLQTSKASGLDLTFVSHLFWP--ILGIWALTLIILYGGVKKGVELSNKI--FM 181 Query: 259 ALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGL 318 L +V+ IL + + LPGA+ G+ + TP++S + + +VW A FF+LS +G + Sbjct: 182 PLL-FVLFTILVIQSLRLPGAVQGLNAFFTPNWSAMMDYKVWLAAYGHTFFSLSVGFGIM 240 Query: 319 ITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGL 378 +T +SY K N LIV +N +T AG+ IF+ +GF+AH V VV G GL Sbjct: 241 VTYASYLKPKTNLTGSGLIVGFANASTEILAGIGIFAALGFMAHAAGTEVKDVVSGGIGL 300 Query: 379 AFIVYPEVVTRLPI-SPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWV 437 AFI +P++++ L + ++ +LFF L G+ S +++E A+ D+ R+K V Sbjct: 301 AFIAFPKIISSLGAGADVFGLLFFSSLFVAGISSMVSILEVPIAAMQDKLKWGRKKA--V 358 Query: 438 VFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAW 486 I + +F++ + + + ++D + N ++ A+ I +AW Sbjct: 359 TIIGGGSAVVSIFLFSSVNAIKLVDIIDHFINNIGIIGGALLSIITVAW 407 Score = 94.3 bits (224), Expect = 9e-18 Identities = 43/121 (35%), Positives = 61/121 (50%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 R NW+ R F N+WRFPY+ Y NGGGAFLIP+ + L+ AGLPL+F++ + Sbjct: 5 RENWSSRSGFIIAAVGSAVGLGNIWRFPYVAYENGGGAFLIPYLLALITAGLPLLFLDYA 64 Query: 86 FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQL 145 G P Y K LG+ V V ++ LYY ++ W Y+ S ++ Sbjct: 65 VGHKGNASPPKAYRKLFKGGETLGWWQVCVCIVIGLYYASVLTWAGSYIYFSVGQMWGSN 124 Query: 146 P 146 P Sbjct: 125 P 125 >UniRef50_Q5ARW4 Cluster: Transporter; n=7; Pezizomycotina|Rep: Transporter - Emericella nidulans (Aspergillus nidulans) Length = 799 Score = 128 bits (308), Expect = 6e-28 Identities = 73/253 (28%), Positives = 129/253 (50%), Gaps = 6/253 (2%) Query: 237 WVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGI-LFYLTPDFSQLA 295 W ++++ + +GV +G+VVY+T P V +I R ++L A G+ L + T QLA Sbjct: 196 WFLIWVSIFRGVGLTGRVVYWTMGLPIVTTIIFVGRSLSLENASEGVKLLWATWRGGQLA 255 Query: 296 NAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFS 355 + VW A Q+FF+ +G + +SYN +N +D+L++ SN+ FA +F Sbjct: 256 SGTVWQTAVGQVFFSTGIGFGYFTSYASYNAKHSNAVMDALLICGSNVLFENFAAFAVFG 315 Query: 356 VIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFAL 415 V+G+L H D V + F+ PE V +P S W+IL F L+ LG S F + Sbjct: 316 VVGYL-HRW--PEDGVRLGAFVVGFLTLPEAVLHMPGSNFWAILLFFTLVVLGFSSAFVM 372 Query: 416 METVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLI 475 ++ V T ++D + + +V ++ + +L L + T G Y L +D++ N ++ Sbjct: 373 LDAVATLVVD--SGLKVSRPIIVTVLTLISFLMCLPYCTEFGFYLLDGIDRWINNICLIF 430 Query: 476 IAIGECILIAWIY 488 + E + + +Y Sbjct: 431 VVWSEVVSASTVY 443 Score = 78.2 bits (184), Expect = 6e-13 Identities = 41/133 (30%), Positives = 64/133 (48%), Gaps = 3/133 (2%) Query: 16 APLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIA 75 AP ++ E R W R F N+ R+P + YNN G + IP+ + + Sbjct: 15 APPPKQSEDGRDQWPSRAAFLLAAMGGCAGQGNLIRYPSVVYNNYGLQWFIPYFLAIFFV 74 Query: 76 GLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMT 135 +P + +E+S GQ G V +N +G+G G ++VS IV Y+ + +AW + Y Sbjct: 75 AIPALILEISIGQAYRGGTVIAFNNINRRLKGVGIGPILVSFIVTQYFTVNLAWIMNYFR 134 Query: 136 VSFSSIFYQLPWQ 148 SF S LPW+ Sbjct: 135 NSFRS---PLPWE 144 >UniRef50_UPI0000D66570 Cluster: PREDICTED: similar to orphan neurotransmitter transporter NTT5; n=6; Murinae|Rep: PREDICTED: similar to orphan neurotransmitter transporter NTT5 - Mus musculus Length = 690 Score = 126 bits (303), Expect = 2e-27 Identities = 87/343 (25%), Positives = 160/343 (46%), Gaps = 38/343 (11%) Query: 19 SEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLP 78 S E P R W + ++ V RF + G +F I + +ML+ G+P Sbjct: 66 SSEGYPPRQLWASKVEYMLAIMSYLLMPSGVLRFASGWVHKGSCSFFIAYILMLLGIGIP 125 Query: 79 LMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSF 138 L+F+E++ GQ A ++ P F G+GY MV+V I Y N+ +W +FYM+ F Sbjct: 126 LLFLEMAVGQRAQQSSADMWKNLSPWFGGVGYSMVMVCFITNTYLNVFNSWILFYMSHIF 185 Query: 139 SSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTA 198 ++ +PW C + ++ +++ ECE T Y + ++ S I Sbjct: 186 ---YFVVPWDQCPLQ---RNSSNFD--PECE--QATSYTYFWYRKTLKASDRI------- 228 Query: 199 LRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFT 258 + F+ LG+S L ++ CL+ A+++ G++S GKV++ Sbjct: 229 --EDGGQPSFS---LGMS----------LFLSFCLICAFLV------NGIKSIGKVLFVL 267 Query: 259 ALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGL 318 L PY ++V R +++ GA G+ L + +++ +W A +Q+ F + +G + Sbjct: 268 LLVPYSIIVCFLIRTLSMDGAEYGLKHLLILKVASISDLTIWCHAGIQVLFDIGLGFGPI 327 Query: 319 ITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLA 361 ++L+S+ NNC D+ ++A+ I T + S++GF A Sbjct: 328 VSLASHVPDFNNCMADAFLMALFKIITLLMTTPFLLSILGFWA 370 Score = 93.1 bits (221), Expect = 2e-17 Identities = 55/163 (33%), Positives = 90/163 (55%), Gaps = 5/163 (3%) Query: 380 FIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVF 439 F+++ EV++ LP S W +LFF++LLTLGL S M + D FP R++ ++ Sbjct: 450 FLIFTEVISLLPGSGFWIVLFFLLLLTLGLCSNLMFMLGNVLTLQDTFPFCRRQPRLLIV 509 Query: 440 IVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQR 499 V++ +L GLIF SG+Y+ L+ + V+II I E + +AW YGA++F D+ Sbjct: 510 CVSMAMFLCGLIFIQPSGIYYFSLLSECWVAVPVIIIIICENLAVAWAYGADRFLADMVA 569 Query: 500 MIGRQSKLWVYLWSAMWRIITPAALVFIL--VFNWIEYKPASY 540 ++GR W +W I+P ++ +L VF ++ P Y Sbjct: 570 LLGRPIFSGCG-W--LWCYISPMVVLGLLTSVFVYLVKGPLVY 609 >UniRef50_O18300 Cluster: Transporter; n=1; Caenorhabditis elegans|Rep: Transporter - Caenorhabditis elegans Length = 669 Score = 125 bits (302), Expect = 3e-27 Identities = 105/482 (21%), Positives = 207/482 (42%), Gaps = 39/482 (8%) Query: 61 GGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVM 120 GGAF++ + ++L++ G P++++EL GQ+ P + P+ +G G+ M +VS++ + Sbjct: 49 GGAFILAYGLILIMLGYPVLYLELIIGQFHRCSPWIFIRRCAPILQGFGF-MALVSAVTI 107 Query: 121 LY-YNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQ 179 LY Y +A ++ +PW C W+T E QN + Sbjct: 108 LYPYQYSVARAFKFLLSLARYRSQDMPWSTCGNWWNT-------ETGHIVFQN------K 154 Query: 180 CFNQSYSVSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVI 239 C N+ T + A+ + Y N + + G+A + W+ Sbjct: 155 CVNE--------TKIKMEAVESAEIQ-YLRNVIHRIGVSHMSFTNFNYGIAYSIFIIWLT 205 Query: 240 VFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQV 299 + + + ++Y +F +++ L R + L GAI G+ L ++++L +++ Sbjct: 206 ISFVQNRVNTRTTPLIYIPTVFAFLICHFLLVRSLHLDGAIEGVQEMLRIEWAELLYSKI 265 Query: 300 WGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIG- 358 W DA + +LS GG ++S+ N + + + + + S ++S++G Sbjct: 266 WIDALNLVVQSLSIGIGGHTVMASFAPPEKNTFRVATLAVILDTGLSIIISATVYSILGY 325 Query: 359 --FLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPI-SPLWSILFFVMLLTLGLDSQFAL 415 F+ +V V+ G L +P ++ ++ S LW L++ L+ +G S + Sbjct: 326 TRFILGRKSVYDLTVLPNGLLLTHSTFPVLLRQVAANSWLWVFLYYSTLVVVGWKSCALI 385 Query: 416 METVTTAILDRFPNFRQKKGW----VVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANW 471 M+T+T I D F N + K + +F+ V G + + +Y + D Sbjct: 386 MKTITVTIADIF-NIKMKTYFFDCLCIFVSMVIATSGLFLCFESGPLYLTMIQDIQTVAT 444 Query: 472 SVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSK-LW--VYLWSAMWRIITPAALVFIL 528 + I A E ++ +YG + GDI ++G+ S W Y W +W+ A F + Sbjct: 445 GIFITA--ELFIVLELYGLDTIYGDIHELMGQPSNDQWSRAYTW-PIWKWRWTTAPAFSI 501 Query: 529 VF 530 +F Sbjct: 502 IF 503 >UniRef50_Q4TJ95 Cluster: Transporter; n=1; Tetraodon nigroviridis|Rep: Transporter - Tetraodon nigroviridis (Green puffer) Length = 310 Score = 124 bits (300), Expect = 5e-27 Identities = 52/141 (36%), Positives = 76/141 (53%), Gaps = 4/141 (2%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 ER W + ++ NVWRFP+LC+ NGGG FL+P+ ++ GLPL +E Sbjct: 1 ERDQWAKKREYILASAGNIVGLGNVWRFPFLCFKNGGGVFLLPYCFFTLLCGLPLFLLET 60 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 GQY G V + K CPL +G+GY +++ I Y++++AW +FY+ SFS Sbjct: 61 VVGQYTQEGAVTCWTKICPLAQGIGYYTMVI-QIYFRVYSIVLAWAVFYLIYSFSG---T 116 Query: 145 LPWQNCKAEWSTKHCYSYEEA 165 LPW +C W+T C A Sbjct: 117 LPWASCSNPWNTDRCVDLSTA 137 >UniRef50_Q4SIS0 Cluster: Transporter; n=2; Tetraodontidae|Rep: Transporter - Tetraodon nigroviridis (Green puffer) Length = 1250 Score = 124 bits (300), Expect = 5e-27 Identities = 58/107 (54%), Positives = 76/107 (71%) Query: 255 VYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPA 314 VY TA FPY+VL I RG+TL GA G+ + TP ++ L N QVW DAA QIFF+LS A Sbjct: 839 VYVTATFPYLVLTIFLVRGLTLDGATVGLTYLFTPKWNTLLNPQVWLDAATQIFFSLSVA 898 Query: 315 WGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLA 361 +GGLI+ +SYN+ NNC D+LIV + N ATS +A + +FS++GF A Sbjct: 899 FGGLISFASYNEEKNNCERDALIVGIINSATSLYASISVFSILGFKA 945 Score = 117 bits (281), Expect = 1e-24 Identities = 67/177 (37%), Positives = 99/177 (55%), Gaps = 11/177 (6%) Query: 375 GAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAI--LDRFPNFRQ 432 G GLAFI + E V +P S +W+ILFF+ML TLGL S F ME +TT + L+ P + Sbjct: 1009 GTGLAFIAFTEAVIEMPASQVWAILFFIMLFTLGLSSMFGNMEGITTPLKDLNVLPKWMP 1068 Query: 433 KKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEK 492 + I+ + + LIFT SG YW+++ + Y + +L+IA E I +++IYG K Sbjct: 1069 NE-VTSGILCLVSFSVALIFTQGSGNYWVEVFNGYVGSVPLLLIAFFEIIAVSYIYGIRK 1127 Query: 493 FCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKP-ASYGHYVYPMW 548 F D+ M G + ++ W A W +I+P L+ + VF I Y + H VYP W Sbjct: 1128 FSEDLDYMNGSRPNIF---WKACWLVISP--LMLLTVF--IAYVALQAQNHPVYPTW 1177 Score = 116 bits (278), Expect = 3e-24 Identities = 53/125 (42%), Positives = 69/125 (55%), Gaps = 3/125 (2%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 R W R + N+WRFPYLC +GGGAFLIP+ + LV GLPL+++EL+ Sbjct: 671 RPKWDNRVQYLLSCIGFAVGLGNIWRFPYLCQIHGGGAFLIPYLIALVFEGLPLLYLELA 730 Query: 86 FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQL 145 GQ G + V+ PL G+G +IVS V L+YN IIAW ++Y SF L Sbjct: 731 IGQRMRKGSIGVWRTISPLLGGVGMASMIVSFCVCLFYNTIIAWVLWYFFHSFQD---PL 787 Query: 146 PWQNC 150 PW C Sbjct: 788 PWSQC 792 Score = 92.3 bits (219), Expect = 4e-17 Identities = 44/121 (36%), Positives = 74/121 (61%), Gaps = 3/121 (2%) Query: 374 QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAI--LDRFPNFR 431 +G GLAFIV+ E +T++P SP+WS+LFFVMLL LG+ + F +E V + L+ FP Sbjct: 259 EGTGLAFIVFTEAITKMPGSPIWSVLFFVMLLCLGISTLFGNIEGVVVPLKDLNIFPKTW 318 Query: 432 QKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAE 491 + + + ++ ++F NSG+YW+ L D +A + +L I + E I + ++YG + Sbjct: 319 PHE-VLTGTTCLVAFIITILFAQNSGLYWVTLFDNFAGSIPLLTIGLCEMIAVVYVYGID 377 Query: 492 K 492 + Sbjct: 378 R 378 Score = 78.2 bits (184), Expect = 6e-13 Identities = 33/91 (36%), Positives = 48/91 (52%) Query: 18 LSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGL 77 + +E R W + + NVWRFPYLC ++GGGAFLIP+ ++LV+ G Sbjct: 23 MEKEDAGNRPKWDNKIQYILTCVGFCIGLGNVWRFPYLCQSHGGGAFLIPYLILLVLEGT 82 Query: 78 PLMFMELSFGQYAALGPVAVYNKFCPLFRGL 108 PL+ +E + GQ G V V+ P G+ Sbjct: 83 PLLLLEFAIGQRLRRGSVGVWRSISPYLAGI 113 Score = 77.0 bits (181), Expect = 1e-12 Identities = 35/72 (48%), Positives = 47/72 (65%) Query: 292 SQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGL 351 ++LAN W DA Q+F+A AWGGLI+ SSYN NNC D++I++V TS +A Sbjct: 125 NELANPTTWLDAGAQVFYAFGLAWGGLISFSSYNSVHNNCVQDAIILSVVTGFTSVYAAT 184 Query: 352 VIFSVIGFLAHE 363 V +S+IGF A E Sbjct: 185 VTYSIIGFRATE 196 Score = 64.1 bits (149), Expect = 1e-08 Identities = 33/71 (46%), Positives = 45/71 (63%), Gaps = 3/71 (4%) Query: 374 QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK 433 +G GLAFIV+ E +T++P SP+WS+LFFVMLL LG+ + F +E V + D N + Sbjct: 570 EGTGLAFIVFTEAITKMPGSPIWSVLFFVMLLCLGISTLFGNIEGVVVPLKDL--NILSQ 627 Query: 434 KGWVVFIVAVF 444 K W V VF Sbjct: 628 K-WPQEAVTVF 637 >UniRef50_A4VB21 Cluster: Transporter; n=1; Platynereis dumerilii|Rep: Transporter - Platynereis dumerilii (Dumeril's clam worm) Length = 124 Score = 124 bits (298), Expect = 1e-26 Identities = 53/103 (51%), Positives = 77/103 (74%), Gaps = 4/103 (3%) Query: 57 YNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVS 116 Y NGG +FLIP+ +ML+ AGLPL FME++ GQ+ +LGP++V+ + P F GLG+ MVI+S Sbjct: 3 YANGGASFLIPYVIMLLFAGLPLFFMEMALGQFTSLGPISVW-RVAPFFSGLGWAMVIIS 61 Query: 117 SIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHC 159 +V +YYN+IIA+T++Y+ SF+S +LPW +CK EW C Sbjct: 62 FLVCIYYNMIIAYTLYYIFASFTS---RLPWSDCKEEWLEFGC 101 >UniRef50_UPI0000EBDBFC Cluster: PREDICTED: similar to orphan neurotransmitter transporter NTT5; n=2; Bos taurus|Rep: PREDICTED: similar to orphan neurotransmitter transporter NTT5 - Bos taurus Length = 615 Score = 122 bits (294), Expect = 3e-26 Identities = 98/359 (27%), Positives = 172/359 (47%), Gaps = 48/359 (13%) Query: 12 EKSKAPLSEEIEP--ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFT 69 EK + P E+ E R W+ + ++ ++W F YL ++GGG FLI + Sbjct: 59 EKVQVPEKEKSEVLITRPFWSNKAEYLLAQMGYTMRPASLWSFCYLWLHSGGGIFLIIYI 118 Query: 70 VMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAW 129 +L + G+PL+F+E++ GQ G + V+ P G+GY +V I L+ N++ AW Sbjct: 119 FLLFLIGIPLLFLEMAAGQRMRQGNIGVWKVISPWIGGVGYTSFMVCFINGLFLNVVTAW 178 Query: 130 TIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYL--RQCFNQSYSV 187 +FY++ SF Y +PW+ C ++ ++ EC T Y R S S+ Sbjct: 179 ILFYLSQSFQ---YPVPWEKCPL---LENASGFD--PECARTTPTLYFWYRMTLKASDSI 230 Query: 188 SHNITALAKTALRRPPAEEYFTNQVLG--LSSGIEETGEIRLGMAMCLLAAWVIVFLCLC 245 + + L P + + +LG + +G++ TG++ MC+L Sbjct: 231 EDDGPPVFSLCL---PL--FLSVCLLGVFMLNGLKWTGKV-----MCVL----------- 269 Query: 246 KGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAV 305 V SSG + + +VV I+ L GA+ G+ + S + N VW A Sbjct: 270 --VSSSGLI-----MLCFVVRSIM------LEGAVFGLHYMTIVKISAIYNVNVWRGAGN 316 Query: 306 QIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHEL 364 Q+ +L +G +I+++S+ + S++C D++IVA++N+ + IFSV+GF A +L Sbjct: 317 QVLCSLGLGFGSIISIASHIQSSSSCLNDAVIVALANLISMMLVTPFIFSVLGFWATQL 375 Score = 66.1 bits (154), Expect = 3e-09 Identities = 36/133 (27%), Positives = 67/133 (50%), Gaps = 3/133 (2%) Query: 397 SILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNS 456 S LFF+MLL L + + +M+++ T++ D F + ++ +V + +L GL FT S Sbjct: 449 SFLFFLMLLNLEMSTMIGIMDSIITSLQDIFISVQKYTKLFTVVVLMIMFLCGLFFTRPS 508 Query: 457 GMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMW 516 G Y+++L+ Y ++I+ I E + + W A F D+ + G + W +W Sbjct: 509 GSYYIRLLTDYWTILPIIIVIIFENLAVKWAREASSFFADMANLWG-HPMYSIIRW--LW 565 Query: 517 RIITPAALVFILV 529 + P L+ + V Sbjct: 566 SYLIPVVLLALSV 578 >UniRef50_Q8IGR3 Cluster: Transporter; n=3; Drosophila melanogaster|Rep: Transporter - Drosophila melanogaster (Fruit fly) Length = 641 Score = 120 bits (290), Expect = 9e-26 Identities = 112/485 (23%), Positives = 205/485 (42%), Gaps = 42/485 (8%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGA-FLIPFTVMLVIAGLPLMFMEL 84 RG W DF +GG F+I + + ++ LP+ ++ Sbjct: 84 RGRWAKSADFYFASCTHAFSSLIFSELSTFGILHGGWLLFIIAYLMGMLFYSLPIFLIQA 143 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 GQ+++ G ++ + + P+F+G+GY +++++ + YY++ + Y + +SI Sbjct: 144 FLGQFSSSGTISAF-RVAPIFKGIGYAILLLNLGTLTYYSIAAVVPLIY---TVNSIHPV 199 Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPA 204 +PW +C W+T+ C +E D Y V + T Sbjct: 200 IPWMSCNNSWNTQECSLHENYDV---------------DDYRVDPHSTV----------- 233 Query: 205 EEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264 E+F + + + G + I M + +L+ W++V L K V GKV+ + + + Sbjct: 234 -EFFRSMIASTAKG-STSMSISWSMLIGVLSIWLVVLALLLKPVAFIGKVLRCSCVLMFG 291 Query: 265 VLVILFFRGVTLPGAIT--GILFYLTPDFSQLANAQVWGDAAVQIFF-ALSPAWGGLITL 321 V +F + + IT + +Y P + A+ + AL P WG +ITL Sbjct: 292 FFVAVFLY-LLIHEQITFDTLHYYWMPQLDSFDSILATARTALLMAGGALGPGWGSIITL 350 Query: 322 SSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAF- 380 SSYN F + S+ V +++I T GL+ +V + + VD+ + F Sbjct: 351 SSYNNFRRDAERLSIWVCLTHI-TIGLMGLLCCNVAHDHFEDHVGMMPLHVDEKHHMQFL 409 Query: 381 -IVYPEVVTRLPISP-LWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVV 438 + + + R +P LW+ LFF M+ L + M +V TA+ D F R ++ V+ Sbjct: 410 YLCFSYLFGRFTTTPNLWAFLFFGMIFLSELCALIIQMMSVITALFDEFETLRSRRILVI 469 Query: 439 FIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQ 498 + + F T G L + A +LI I ++ W+YG +F D+Q Sbjct: 470 SSLVFCLTASSVYFCTQLGFSQLTQLPNLAVFTHLLISGI-LVLMTTWVYGRVRFQCDLQ 528 Query: 499 RMIGR 503 M+G+ Sbjct: 529 FMLGK 533 >UniRef50_Q2VFP2 Cluster: GABA-a receptor 3-like protein; n=1; Mytilus galloprovincialis|Rep: GABA-a receptor 3-like protein - Mytilus galloprovincialis (Mediterranean mussel) Length = 127 Score = 119 bits (286), Expect = 3e-25 Identities = 54/97 (55%), Positives = 71/97 (73%) Query: 196 KTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVV 255 +T + P+EE++ N+ L ++ GIE G IR + +CL AWV+VFLCLCKGV+SSG+VV Sbjct: 30 ETVKQITPSEEFWENRALKMTDGIENFGGIRWELLICLTIAWVLVFLCLCKGVKSSGRVV 89 Query: 256 YFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFS 292 Y TA FPY+VL+IL RGVTLPGA G+ FYL P + Sbjct: 90 YVTATFPYLVLLILLIRGVTLPGASEGLKFYLIPQMT 126 >UniRef50_UPI000059FF44 Cluster: PREDICTED: similar to Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5 (Solute carrier family 6 member 16); n=8; Laurasiatheria|Rep: PREDICTED: similar to Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5 (Solute carrier family 6 member 16) - Canis familiaris Length = 798 Score = 117 bits (282), Expect = 8e-25 Identities = 49/131 (37%), Positives = 78/131 (59%), Gaps = 3/131 (2%) Query: 20 EEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPL 79 +E ER +W + ++ +WRFPYLC++NGGG+FLI + +ML + G+PL Sbjct: 79 KETPIERPSWANKIEYLLAQVGFSVGLSTIWRFPYLCFHNGGGSFLIIYILMLFLVGVPL 138 Query: 80 MFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFS 139 +F+E++ GQ G + V+ P G+GY ++ IV LYY++++AW++FY+ SF Sbjct: 139 LFLEMAAGQRMRQGSIGVWKVISPWIGGVGYTSFMMCCIVSLYYSVLMAWSLFYLVQSFQ 198 Query: 140 SIFYQLPWQNC 150 Y LPW C Sbjct: 199 ---YPLPWALC 206 Score = 101 bits (242), Expect = 6e-20 Identities = 50/157 (31%), Positives = 84/157 (53%) Query: 207 YFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVL 266 ++ VL + IE G +++ L A W+I+ + + KG + +GK++Y + + PY ++ Sbjct: 228 FWYRHVLKATDEIEMGGLPVTHLSISLFATWLIICISMIKGPKFTGKMLYVSVILPYFII 287 Query: 267 VILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNK 326 L R + L GA G+ L L + +VW QIF ++ P +G +SSY Sbjct: 288 FCLLIRSLMLEGAYFGLKNLLAAKVRSLYSVEVWRRTGNQIFLSMGPGFGSFTAISSYIP 347 Query: 327 FSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHE 363 SNNC +D+ +VA N+ S A L +F+++G LA E Sbjct: 348 QSNNCVMDAFVVAFLNLTASLTATLFVFAIMGHLATE 384 Score = 100 bits (239), Expect = 1e-19 Identities = 61/200 (30%), Positives = 106/200 (53%), Gaps = 8/200 (4%) Query: 334 DSLIVAVSNIATSFFAGL---VIFSVIGFLAH-ELNVSVDRVVDQGAGLAFIVYPEVVTR 389 DSL S+I + +F L + V+ +L++ L + V++ G G+A + + ++++ Sbjct: 414 DSLYHDPSSIYSQWFKSLPEQIKDVVLPYLSNCNLTYQLKEVME-GPGVAIVAFTDIISV 472 Query: 390 LPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGG 449 S WSI+ F+ML LGL + +M + + D F + R+ + + V +LG Sbjct: 473 FSGSTFWSIIIFMMLANLGLSTMIGIMHGIIIPLQDTFSSLRKNIILLTVGICVSLFLGS 532 Query: 450 LIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWV 509 LIF SG Y++ L+D Y A+ + + I E I IAWIYGA +F D+ M+GR + Sbjct: 533 LIFVRPSGSYYVNLLDDYWASLPLFLTVILENIAIAWIYGARRFLADLIIMLGRPISP-I 591 Query: 510 YLWSAMWRIITPAALVFILV 529 Y W +W ++P L+ + + Sbjct: 592 YRW--LWCFLSPFVLLVLFL 609 >UniRef50_Q4SNN3 Cluster: Transporter; n=1; Tetraodon nigroviridis|Rep: Transporter - Tetraodon nigroviridis (Green puffer) Length = 559 Score = 117 bits (281), Expect = 1e-24 Identities = 69/218 (31%), Positives = 102/218 (46%), Gaps = 34/218 (15%) Query: 17 PLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAG 76 P ++ RG W + ++ NVWRFPYLCY NGG + G Sbjct: 8 PKKQKAGGARGQWASKTEYILVVAGQVVGLGNVWRFPYLCYKNGG------------VCG 55 Query: 77 LPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTV 136 +PL +E S GQ+ G + + K CPL +G+GYG ++ + + +I AW +FY+ Sbjct: 56 IPLFLLETSLGQFTQEGFITCWRKICPLAQGIGYGQLLF-KVYGFVFVIIQAWALFYLVF 114 Query: 137 SFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAK 196 SF S +LPW C W+T +C S + D + S + N T L Sbjct: 115 SFRS---ELPWVTCNNSWNTANCRSLQAVD---------------SSSVNYITNQTVLPN 156 Query: 197 TALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLL 234 T+ A E+ +VLGLS GIEE G + +G + L+ Sbjct: 157 TS---TAATEFLERRVLGLSRGIEELGGVSVGSGVLLV 191 Score = 102 bits (244), Expect = 3e-20 Identities = 46/96 (47%), Positives = 64/96 (66%) Query: 316 GGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQG 375 G L+ L SY+ +NNCY D + + N +TSF AG V+FSV+GF+A E V+V+ VV G Sbjct: 187 GVLLVLGSYSPSNNNCYRDCFWLCLLNSSTSFVAGFVVFSVLGFMAEEQGVAVNTVVRSG 246 Query: 376 AGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDS 411 GLAFI YP+ LP+ WS+ FF+ML+ L +D+ Sbjct: 247 PGLAFIAYPQATALLPLPQFWSVCFFLMLILLAVDT 282 Score = 60.5 bits (140), Expect = 1e-07 Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 20/113 (17%) Query: 144 QLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPP 203 Q+PW C W+T C Y++ S N+T T + Sbjct: 349 QIPWATCNNPWNTDKCRVYQDLSPA-------------------SSNLTGNETTQMNATT 389 Query: 204 AE-EYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVV 255 A E++ ++L +S GIEE G + + +CLLA+WV + + KGV+SSGK V Sbjct: 390 AATEFWERRMLRMSGGIEEVGSVSWELTLCLLASWVFCYFSIWKGVRSSGKFV 442 Score = 44.8 bits (101), Expect = 0.007 Identities = 26/98 (26%), Positives = 44/98 (44%), Gaps = 4/98 (4%) Query: 396 WSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK---KGWVVFIVAVFGYLGGLIF 452 W +F + + +F +E+ T + D FP + K + V +V +L L+ Sbjct: 424 WVFCYFSIWKGVRSSGKFVDVESFITTVSDMFPKWFHKPMRQEIFVLVVCASAFLVQLLL 483 Query: 453 TTNSGMYWLQLMDKYAANWSV-LIIAIGECILIAWIYG 489 T G+Y Q D YA+ AI EC+ + W++G Sbjct: 484 VTQGGIYIFQFFDYYASTRICGYFFAICECLALGWMFG 521 >UniRef50_Q17EZ3 Cluster: Sodium/shloride dependent amino acid transporter; n=1; Aedes aegypti|Rep: Sodium/shloride dependent amino acid transporter - Aedes aegypti (Yellowfever mosquito) Length = 331 Score = 111 bits (267), Expect = 5e-23 Identities = 51/131 (38%), Positives = 75/131 (57%), Gaps = 4/131 (3%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 ER W +F NVWRFP++ NGGGAF+IP+ ++L++ G P+ +ME+ Sbjct: 72 ERDQWGKGIEFLMSCIAMSVGLGNVWRFPFIALQNGGGAFVIPYIIVLLLVGKPVYYMEM 131 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144 GQ+++ G V VY+ P RG+GYG V+ +IV YY ++A T+ Y+ SF I Sbjct: 132 IIGQFSSRGSVKVYD-CAPAMRGVGYGQVLSIAIVSTYYASLMATTLKYLFESFQKI--- 187 Query: 145 LPWQNCKAEWS 155 LPW C W+ Sbjct: 188 LPWATCDDSWA 198 Score = 43.2 bits (97), Expect = 0.022 Identities = 20/57 (35%), Positives = 32/57 (56%), Gaps = 3/57 (5%) Query: 101 FCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTK 157 F +G+G+G + + ++ YY+ ++A YM SF S LPW NC+ EW T+ Sbjct: 247 FIKHIKGVGFGQLFSVTSLITYYSSLMALIGRYMYESFKS---PLPWANCRPEWGTE 300 >UniRef50_A3CV46 Cluster: Transporter; n=1; Methanoculleus marisnigri JR1|Rep: Transporter - Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) Length = 431 Score = 109 bits (263), Expect = 2e-22 Identities = 86/277 (31%), Positives = 136/277 (49%), Gaps = 21/277 (7%) Query: 260 LFPYVVLVILFFRGVTL--PGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGG 317 L P +++++LF V+L PGA GI FYL+PDFS+L + VW A Q FF+LS G Sbjct: 161 LIPVLLVILLFLVAVSLTEPGAAEGIGFYLSPDFSRLTDPAVWIAAFGQAFFSLSVGMGI 220 Query: 318 LITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAG 377 L+T SY K + ++ I+A +++ + AGLVIF ++ +D G Sbjct: 221 LLTFGSYLK-REALFRNAAIIAAADMLIAVLAGLVIFPLV------FTAGLDPAA--GVN 271 Query: 378 LAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWV 437 LAFI P T + + LFF+ML L S +++E T A++D + R++ + Sbjct: 272 LAFITLPTAFTEIRYGMVLGTLFFLMLFAAALTSAVSMLEVPTAALMDSYGYPRKRATLL 331 Query: 438 VF-IVAVFGYLGGLIFTTNS----GMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEK 492 VF V +FG L +T + GM +L L D +++ + I+ W + Sbjct: 332 VFAAVMLFGLPSALSYTALNLEALGMPFLDLADYVFGTIGLIVAGLIISIVGGWFMTRTR 391 Query: 493 FCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILV 529 +I G Q K+++ A+ R PA L+ LV Sbjct: 392 IYAEIGG-CGWQQKVYM----ALIRYGVPAVLLITLV 423 Score = 87.4 bits (207), Expect = 1e-15 Identities = 38/109 (34%), Positives = 58/109 (53%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 ER W+ F N+WRFPY+ NGGGAFLIPF + +++ GLPLM +EL Sbjct: 2 EREEWSSTLGFILASIGSAVGIGNIWRFPYVVGANGGGAFLIPFLIAVLLFGLPLMVLEL 61 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFY 133 + G+ ++ + F G +V V S+++ YY +I +W + Y Sbjct: 62 AIGRSTGTSVISAFRSIRQRFAAAGLVIVAVVSLILGYYLVITSWVLAY 110 >UniRef50_Q9GZN6 Cluster: Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5; n=9; Eutheria|Rep: Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5 - Homo sapiens (Human) Length = 736 Score = 102 bits (244), Expect = 3e-20 Identities = 56/210 (26%), Positives = 114/210 (54%), Gaps = 6/210 (2%) Query: 335 SLIVAVSNIATSFFAGLV--IFSVIGFLAHELNVSVDRV-VDQGAGLAFIVYPEVVTRLP 391 +L+ ++I ++ +GL I S++ E N+ + +G AF+ + E ++ LP Sbjct: 433 NLLYNPTSIYNAWLSGLPQHIKSMVLREVTECNIETQFLKASEGPKFAFLSFVEAMSFLP 492 Query: 392 ISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLI 451 S WS +FF+MLL +GL S +M+ + T + D F FR+ ++ V + ++ GL Sbjct: 493 PSVFWSFIFFLMLLAMGLSSAIGIMQGIITPLQDTFSFFRKHTKLLIVGVFLLMFVCGLF 552 Query: 452 FTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQ-SKLWVY 510 FT SG Y+++L+ Y + ++++ + E + ++W YGA +F D+ ++G S ++ + Sbjct: 553 FTRPSGSYFIRLLSDYWIVFPIIVVVVFETMAVSWAYGARRFLADLTILLGHPISPIFGW 612 Query: 511 LWSAMWRIITPAALVFILVFNWIEYKPASY 540 LW + ++ ++F+ + + KP +Y Sbjct: 613 LWPHLCPVV--LLIIFVTMMVHLCMKPITY 640 Score = 91.5 bits (217), Expect = 6e-17 Identities = 45/140 (32%), Positives = 75/140 (53%), Gaps = 7/140 (5%) Query: 15 KAPLSEEIEPE----RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTV 70 K ++E+ E E R W+ + ++ +WRF YL N+GG +F + Sbjct: 88 KVQMTEKKESEVLLARPFWSSKTEYILAQVGFSMKPSCLWRFAYLWLNSGGCSFAAIYIF 147 Query: 71 MLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWT 130 ML + G+PL+F+E++ GQ G + V+ P G+GY +V I+ LY+N++ +W Sbjct: 148 MLFLVGVPLLFLEMAAGQSMRQGGMGVWKIIAPWIGGVGYSSFMVCFILGLYFNVVNSWI 207 Query: 131 IFYMTVSFSSIFYQLPWQNC 150 IFYM+ SF + +PW+ C Sbjct: 208 IFYMSQSFQ---FPVPWEKC 224 Score = 84.2 bits (199), Expect = 9e-15 Identities = 49/162 (30%), Positives = 76/162 (46%) Query: 200 RRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTA 259 R P+ ++ Q L S IE+ G + + W +V + G++S+GKV+Y Sbjct: 239 RTTPSIYFWYQQALKASDRIEDGGSPVYSLVLPFFLCWCLVGAFMINGLKSTGKVIYVLV 298 Query: 260 LFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLI 319 L P ++V F R + L GA G+ + S + N VW A Q+ G + Sbjct: 299 LLPCFIIVGFFIRTLLLEGAKFGLQQLVVAKISDVYNMSVWSLAGGQVLSNTGIGLGSVA 358 Query: 320 TLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLA 361 +L+SY SNNC D+ +V+V N+ T F V+GF A Sbjct: 359 SLASYMPQSNNCLSDAFLVSVINLLTLLVFTSFNFCVLGFWA 400 >UniRef50_UPI000059FF45 Cluster: PREDICTED: similar to solute carrier family 6, member 20 isoform 2; n=1; Canis lupus familiaris|Rep: PREDICTED: similar to solute carrier family 6, member 20 isoform 2 - Canis familiaris Length = 686 Score = 100 bits (240), Expect = 1e-19 Identities = 39/103 (37%), Positives = 66/103 (64%), Gaps = 3/103 (2%) Query: 48 NVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRG 107 ++WRFPYLC+ NGGG F++ + ML++ G+PL++ME+ G + + + V+ + P G Sbjct: 61 SIWRFPYLCHRNGGGNFILMYFFMLLLFGIPLLYMEMIMGHWLRMDNIRVWKQLVPWLGG 120 Query: 108 LGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNC 150 +GY ++V ++ LY ++II W+I Y+ SF + LPW C Sbjct: 121 IGYASILVCILISLYNSIIITWSISYLGNSFDN---SLPWNQC 160 Score = 51.6 bits (118), Expect = 6e-05 Identities = 28/99 (28%), Positives = 53/99 (53%), Gaps = 4/99 (4%) Query: 433 KKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEK 492 K + ++ + G+LG L+FT+++G Y + L D Y +++II + + +A IYGA + Sbjct: 446 KPAFATVLICLGGFLGSLVFTSHAGSYIMSLFDDYLIPLTLVIIVTFQNVALACIYGARR 505 Query: 493 FCGDIQRMIGRQSKLWVYLWSAMWRIIT-PAALVFILVF 530 +I +GR LW + + +W +T P L ++ Sbjct: 506 VREEIFSDLGR--LLWSF-FIVLWCYVTLPGLLALTTIY 541 Score = 49.2 bits (112), Expect = 3e-04 Identities = 18/59 (30%), Positives = 37/59 (62%) Query: 374 QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQ 432 +G GLAF+ + +V++ P + W+ILFF+ L+ +GL + ++E + + + + FR+ Sbjct: 340 EGPGLAFVAFSQVISLFPGASFWAILFFLALVIMGLSTSIQILEGIVSPLQNSISTFRR 398 >UniRef50_O67854 Cluster: Transporter; n=1; Aquifex aeolicus|Rep: Transporter - Aquifex aeolicus Length = 513 Score = 100 bits (240), Expect = 1e-19 Identities = 88/308 (28%), Positives = 135/308 (43%), Gaps = 13/308 (4%) Query: 244 LCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPG-AITGILFYLTPDFSQLANAQVWGD 302 + KG++ K+ T V LVI F T G A G+ F TPDF +L + VW Sbjct: 187 ISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIA 246 Query: 303 AAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAH 362 A QIFF LS +G +IT +SY + + + L A N G I S+ +A Sbjct: 247 AVGQIFFTLSLGFGAIITYASYVRKDQDIVLSGLTAATLNEKAEVILGGSI-SIPAAVAF 305 Query: 363 ELNVSVDRVVDQGA-GLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTT 421 + + GA L FI P + ++ L+F +L GL S A+M+ + Sbjct: 306 FGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSSIAIMQPMIA 365 Query: 422 AILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGEC 481 + D +K V++ A+ + L+ N L MD +A V+ + E Sbjct: 366 FLEDELK--LSRKHAVLWTAAIVFFSAHLVMFLNKS---LDEMDFWAGTIGVVFFGLTEL 420 Query: 482 ILIAWIYGAEKFCGDIQR-MIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASY 540 I+ WI+GA+K +I R I + +++ Y + R ITPA L +LV EY P Sbjct: 421 IIFFWIFGADKAWEEINRGGIIKVPRIYYY----VMRYITPAFLAVLLVVWAREYIPKIM 476 Query: 541 GHYVYPMW 548 + +W Sbjct: 477 EETHWTVW 484 Score = 61.3 bits (142), Expect = 8e-08 Identities = 36/116 (31%), Positives = 56/116 (48%), Gaps = 6/116 (5%) Query: 22 IEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMF 81 +E +R +W R N RFP NGGGAF+IP+ + ++ G+PLM+ Sbjct: 1 MEVKREHWATRLGLILAMAGNAVGLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMW 60 Query: 82 MELSFGQY-AALGPVAVYNKFCPLFRG-----LGYGMVIVSSIVMLYYNLIIAWTI 131 +E + G+Y A G F L+R LG + + +V +YY I +WT+ Sbjct: 61 IEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVAIYYVYIESWTL 116 >UniRef50_UPI0000F2D4C7 Cluster: PREDICTED: hypothetical protein; n=1; Monodelphis domestica|Rep: PREDICTED: hypothetical protein - Monodelphis domestica Length = 718 Score = 99.5 bits (237), Expect = 2e-19 Identities = 86/314 (27%), Positives = 138/314 (43%), Gaps = 62/314 (19%) Query: 50 WRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLG 109 WRFPYLC+ NGGG+F++ + +L G PL+FME++ GQ + + P GL Sbjct: 110 WRFPYLCHENGGGSFIVSYVFLLFAMGFPLIFMEMALGQNLHFSG---WKQIHPRMWGLN 166 Query: 110 YGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECE 169 ++S +++LY Y V SIFY C WS +C Sbjct: 167 LATCLISFMLLLY----------YNAVIAWSIFYLGNSFLCPLPWS-----------QCP 205 Query: 170 A-QNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLG 228 NGT + +C +R P+ ++ + L ++ IEE G + Sbjct: 206 VGANGTSEVLEC------------------VRTRPSIYFWFRETLMVTGSIEEGGGLVFS 247 Query: 229 MAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPG-AITGILFYL 287 + +CLL WV + +G+Q+ GKV RG L +I G+L ++ Sbjct: 248 LTVCLLVVWVSILFIWLQGLQAKGKV-----------------RGGALGAXSIFGMLHFI 290 Query: 288 TPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSF 347 S + + +VW A Q+F + G +I L S NNC D+ ++ +++A+ Sbjct: 291 QIKKSLITSTKVWRQAGAQMFISTGLGIGNIIFLYSCAT-KNNCAQDAFMLTFTHMASCL 349 Query: 348 FAGLVIFSVIGFLA 361 VIFS++GF A Sbjct: 350 LTTQVIFSMLGFQA 363 Score = 99.1 bits (236), Expect = 3e-19 Identities = 49/164 (29%), Positives = 89/164 (54%) Query: 374 QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK 433 QG GL F+ + E VT P S W++LFF++L++ GL+ + ++ T + D FP+ Sbjct: 435 QGPGLVFVAFTEAVTSFPGSSFWAVLFFLLLISQGLNISVSQLQGTLTLLQDIFPSLSNF 494 Query: 434 KGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKF 493 + G+L L+FT SG+Y+L+L D+ A ++I+ E + +AWIYGA++F Sbjct: 495 SLTISVTYCCLGFLCSLLFTQRSGLYFLKLFDEILATLPLIIMIFFETVGVAWIYGAKRF 554 Query: 494 CGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKP 537 ++ M+ + KL + ++ L+ I + ++I +P Sbjct: 555 LDEVWAMLEFKIKLMHEYVLRYYTLLGVMILIIISLLDFIMEQP 598 >UniRef50_UPI0000E49EF2 Cluster: PREDICTED: similar to solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 - Strongylocentrotus purpuratus Length = 275 Score = 99.5 bits (237), Expect = 2e-19 Identities = 46/100 (46%), Positives = 63/100 (63%), Gaps = 2/100 (2%) Query: 8 KGDEEKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIP 67 + + EK+ SEE E ER W + DF NVWRFPYL Y NGGGAFLIP Sbjct: 157 RDEYEKNNDDDSEE-EEERETWGTKVDFLLSVIGFSVDLANVWRFPYLVYRNGGGAFLIP 215 Query: 68 FTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRG 107 + + L+I G+P+++MEL+ GQY G ++V+ K CP+F+G Sbjct: 216 YVLFLLIGGIPMLYMELALGQYNRGGAISVW-KICPIFQG 254 >UniRef50_Q7NXF6 Cluster: Transporter; n=4; Bacteria|Rep: Transporter - Chromobacterium violaceum Length = 440 Score = 99.1 bits (236), Expect = 3e-19 Identities = 67/214 (31%), Positives = 114/214 (53%), Gaps = 15/214 (7%) Query: 246 KGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAV 305 KG+++ K + ALF ++++L RG+TLPGA+ G+ +++ PDFS+++ A + DA Sbjct: 163 KGIEALSKFL-MPALF--ALMLVLIARGLTLPGALEGVSYFVAPDFSKVS-ASMLVDALG 218 Query: 306 QIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELN 365 FF+LS G +IT SY + +L V + +AT F AGL++ + A + Sbjct: 219 LAFFSLSLGLGIMITYGSYVGRESKLLGSALWVILLTVATCFLAGLMVLPAV--FAFGFD 276 Query: 366 VSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILD 425 S G GL FI P V LP+ L++++FF +LL L S +L+E VT+ +D Sbjct: 277 PSA------GPGLTFITMPAVFAHLPLGQLFAVMFFCLLLLAALTSSVSLLEVVTSFAID 330 Query: 426 RFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMY 459 R + ++A +L G+ + + G++ Sbjct: 331 ---ELRLSRRTAAILMAAGTFLLGIPASLSLGVW 361 Score = 74.5 bits (175), Expect = 8e-12 Identities = 36/113 (31%), Positives = 56/113 (49%), Gaps = 1/113 (0%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 R W R F +W+FPY+ NGGGAFL + + + GL LM E++ Sbjct: 3 RSQWGSRLGFILAAAGSAIGLGAIWKFPYVAATNGGGAFLFIYLGICLTLGLVLMLAEMA 62 Query: 86 FGQYAALGPVAVYNKFCPLFRGL-GYGMVIVSSIVMLYYNLIIAWTIFYMTVS 137 G+ + G V + K F L GY V+V +++ +Y+++ WTI Y+ S Sbjct: 63 LGRATSAGAVGAFRKLAGGFWPLIGYMGVLVCFLILSFYSVVGGWTIAYIVKS 115 >UniRef50_UPI0000E4A5E3 Cluster: PREDICTED: similar to creatine transporter, partial; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to creatine transporter, partial - Strongylocentrotus purpuratus Length = 141 Score = 97.9 bits (233), Expect = 7e-19 Identities = 41/81 (50%), Positives = 52/81 (64%), Gaps = 1/81 (1%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 R W+GR DF NVWRFPYLCY NGGGAFLIP+ + V+ G+PL F+E + Sbjct: 62 RERWSGRLDFLLSCVGFAVGLGNVWRFPYLCYKNGGGAFLIPYFICAVLGGIPLFFIEAA 121 Query: 86 FGQYAALGPVAVYNKFCPLFR 106 GQY +LG + + K CPLF+ Sbjct: 122 LGQYTSLGGIKAW-KICPLFQ 141 >UniRef50_A6NZ68 Cluster: Transporter; n=1; Bacteroides capillosus ATCC 29799|Rep: Transporter - Bacteroides capillosus ATCC 29799 Length = 478 Score = 97.9 bits (233), Expect = 7e-19 Identities = 88/331 (26%), Positives = 149/331 (45%), Gaps = 23/331 (6%) Query: 209 TNQVL-GLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSS-GKVVYFTALFPYVVL 266 T VL G S+ +T + G A + L L GV + K+ F +V+ Sbjct: 164 TGSVLSGDSAAFFDTLAVDFGSVPWHFIAVALTVLVLVLGVSAGIEKISKFMMPAFFVLF 223 Query: 267 VILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNK 326 +I+ R LPGA+ G L+ L PD+S L N + W A Q FF+LS G++ SY K Sbjct: 224 LIIAVRVAFLPGAVDGYLYLLKPDWSYLLNPETWIMAMGQAFFSLSINGAGMLIYGSYMK 283 Query: 327 FSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEV 386 S + S++ A+ + + AG I + E G L F+ P+V Sbjct: 284 KSEDIIHHSVVTALLDTMAALLAGFAIIPAVFAFGIE--------PASGPSLMFVTLPKV 335 Query: 387 VTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGY 446 +P L+++LFFV + G+ S ++E A+ R +V +V VFG Sbjct: 336 FQLMPGGQLFALLFFVSVFFAGITSLMNMLEACGAALESNLKLPRWLSTTIVGVV-VFGV 394 Query: 447 LGGLIFTTNSGM-YWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQ- 504 + + SGM WL L+ Y A + ++ A + I W+ G + ++ M+GR Sbjct: 395 --SVFLESLSGMGSWLDLITIYVAPFGAVLGA----VFIYWVLGLDPIKKEL--MLGRDK 446 Query: 505 --SKLWVYLWSAMWRIITPAALVFILVFNWI 533 K + ++ ++ I++ A ++F +++ I Sbjct: 447 PIGKAFDFIAKYVYVILSAAVVIFGIIYGGI 477 Score = 48.0 bits (109), Expect = 8e-04 Identities = 28/127 (22%), Positives = 53/127 (41%), Gaps = 7/127 (5%) Query: 17 PLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAG 76 P+S G + F N+W FPY GGGAFLIP+ + + + Sbjct: 37 PMSHHNSAHSGKFRSSAGFILAAVGSAVGMGNIWLFPYRVGQYGGGAFLIPYFIFVALFS 96 Query: 77 LPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVI-VSSI-----VMLYYNLIIAWT 130 + E + G+ G + ++ + RG G +I + + + + Y++++ W Sbjct: 97 YAGLSGEFALGRLTGTGTIGSFD-YALKIRGKRGGKIIGIMPLLGVLGIAIGYSVVVGWV 155 Query: 131 IFYMTVS 137 + Y+ S Sbjct: 156 LRYIAGS 162 >UniRef50_Q2S448 Cluster: Sodium-and chloride-dependent transporter; n=3; Bacteria|Rep: Sodium-and chloride-dependent transporter - Salinibacter ruber (strain DSM 13855) Length = 507 Score = 97.5 bits (232), Expect = 1e-18 Identities = 93/348 (26%), Positives = 159/348 (45%), Gaps = 34/348 (9%) Query: 207 YFTNQVLGLSSGIEETGE---IRLGM-AMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFP 262 Y VL + G E + +G+ A LL ++V + KG++ K++ LF Sbjct: 169 YAVKDVLAPTMGFEAFAASPWLNVGLVAFFLLLTLLVVVGGVEKGIERWAKIL-LPVLFV 227 Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322 ++LVI+ R VTL GA G+ FYL PDFS++ V A Q FF LS G +IT Sbjct: 228 LILLVIV--RAVTLDGAAEGLRFYLVPDFSEITFDLVIA-ALGQAFFTLSLGMGAMITYG 284 Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIV 382 SY + + V + N + AG +IF + + D G L F+V Sbjct: 285 SYLPKREDIAMSGGYVVLFNTMIALMAGFMIFPAL------FAMGADPAT--GPALVFVV 336 Query: 383 YPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKK----GWVV 438 PEV ++P+ + LFF++L L S +L+E V + +D R+K G + Sbjct: 337 LPEVFAQMPLGGIVEFLFFLLLSIAALTSSISLLEVVVSYFVDEKNWSRRKSVLIIGVIT 396 Query: 439 FIVAV-----FGYLGG---LIFTTNSGMYW-----LQLMDKYAANWSVLIIAIGECILIA 485 F++A+ FG +G L + G + L ++D + + + A + I Sbjct: 397 FLMALPSALSFGAVGAFSDLSYLFGEGGLFGQNNVLGVLDYLIGSAGLAVGAFFLSVFIG 456 Query: 486 WIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWI 533 W++GA++ ++++ + ++ +W R I P +VF +V ++ Sbjct: 457 WVWGADRAADELRQGSSTLADGFLGVWIFGMRYIIP-VVVFGIVMGYL 503 Score = 70.5 bits (165), Expect = 1e-10 Identities = 39/149 (26%), Positives = 67/149 (44%), Gaps = 12/149 (8%) Query: 11 EEKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTV 70 E + P+S +R W+ + F N+WRFPYL GGGAF++ + + Sbjct: 45 EPTRRLPMSTT-STDREQWSSQIGFVLAAAGSAIGLGNIWRFPYLAGEGGGGAFVLIYLL 103 Query: 71 MLVIAGLPLMFMELSFGQYAALGPVAVYNKFC---PLFRGLGYGMVIVSSIVMLYYNLII 127 ++ G+P +F ELS G+ + PV + +G V+ +++ YY+++ Sbjct: 104 CILFIGMPYLFGELSLGRNSQKNPVGAIKSITGGGSAWIVVGGFCVLAGFVILSYYSVVA 163 Query: 128 AWTIFYM-------TVSFSSIFYQLPWQN 149 W + Y T+ F + F PW N Sbjct: 164 GWAVGYAVKDVLAPTMGFEA-FAASPWLN 191 >UniRef50_A7T6E6 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 244 Score = 94.7 bits (225), Expect = 7e-18 Identities = 53/171 (30%), Positives = 91/171 (53%), Gaps = 11/171 (6%) Query: 107 GLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEAD 166 GLGYG +++ + +YY +I+AW +FY+ SF S +PW++C W+T C + Sbjct: 3 GLGYGTLVMQFLSNIYYIVILAWVLFYLFDSFRS---HVPWESCGNWWNTPFCSTRPRNS 59 Query: 167 -------ECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAEEYFTNQVLGLSSGI 219 +C ++Y +Q+ + S + + P+EEY+TN+VL ++ + Sbjct: 60 RLLWVELKCVPHTPSFYFMTA-SQTVNCSAFALPVNCSQTFTSPSEEYWTNRVLQITDSL 118 Query: 220 EETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILF 270 E+ GEIR + L+ +WV+V+ C+ K V+ +GKV + A Y L I F Sbjct: 119 EDMGEIRWELVGTLILSWVLVYFCIFKSVRLTGKVWVYAATQIYWSLGIGF 169 Score = 58.8 bits (136), Expect = 4e-07 Identities = 26/48 (54%), Positives = 35/48 (72%) Query: 377 GLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAIL 424 GL FI YPE +++LP S W+ILFF ML+TLGLD+ L+ +VT I+ Sbjct: 194 GLVFIAYPEAISQLPGSVFWAILFFTMLVTLGLDTMVRLIPSVTGTIV 241 Score = 40.7 bits (91), Expect = 0.12 Identities = 19/51 (37%), Positives = 29/51 (56%) Query: 280 ITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNN 330 ++ +L Y S +VW AA QI+++L +GG+IT S+N F NN Sbjct: 134 LSWVLVYFCIFKSVRLTGKVWVYAATQIYWSLGIGFGGIITFGSFNSFKNN 184 >UniRef50_Q8U3T4 Cluster: Putative transporter; n=1; Pyrococcus furiosus|Rep: Putative transporter - Pyrococcus furiosus Length = 430 Score = 94.3 bits (224), Expect = 9e-18 Identities = 59/201 (29%), Positives = 105/201 (52%), Gaps = 12/201 (5%) Query: 224 EIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGI 283 E L + + + IV + + +G++ + K++ LF V+L++L R VTLP A G+ Sbjct: 139 EALLWLFVVIALTIAIVAMGVQRGIERANKIM-MPLLF--VLLIVLAVRSVTLPNAYEGL 195 Query: 284 LFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNI 343 FYL PD S++A+ + W A Q+FF+LS ++ SY + ++ + ++ A + Sbjct: 196 KFYLLPDLSKIASGKTWMIALSQMFFSLSVLGNTMVVYGSYLREEDDIPLSAIATAFGDT 255 Query: 344 ATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVM 403 A + AG ++F + E G GL F+ P V ++P ++S LFF++ Sbjct: 256 AVAVTAGFIVFPAVFSFGLEPTA--------GPGLVFVTLPMVFQKMPGGMIFSALFFLL 307 Query: 404 LLTLGLDSQFALMET-VTTAI 423 L+ GL S +++E V +AI Sbjct: 308 LIFAGLSSTVSMLEVYVDSAI 328 Score = 68.9 bits (161), Expect = 4e-10 Identities = 33/114 (28%), Positives = 52/114 (45%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 R W R F N+W FP GG AFLIP+ V+L G+ + +E + Sbjct: 6 RETWGSRVGFVAAAIGSAVGLGNIWMFPMRAGLYGGAAFLIPYLVLLFAVGVVALTVEWT 65 Query: 86 FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFS 139 G+ GP+ + K P + LG + + ++ +Y+L++ W I Y S S Sbjct: 66 LGRATKGGPIEAFEKTLPGGKYLGILVNVTILMIFAFYSLVLGWVIRYFIASLS 119 >UniRef50_Q800X8 Cluster: GABA transporter GAT-3; n=9; Euteleostomi|Rep: GABA transporter GAT-3 - Chelydra serpentina serpentina (common snapping turtle) Length = 107 Score = 93.1 bits (221), Expect = 2e-17 Identities = 41/74 (55%), Positives = 54/74 (72%) Query: 203 PAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFP 262 P E++ +VL +S GIE G +R +A+CLLAAW I + C+ KG +S+GKVVY TA FP Sbjct: 34 PVMEFWERRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFP 93 Query: 263 YVVLVILFFRGVTL 276 YV+L+IL RGVTL Sbjct: 94 YVMLLILLVRGVTL 107 >UniRef50_Q9X7H2 Cluster: Transporter; n=5; Neisseria|Rep: Transporter - Neisseria meningitidis Length = 445 Score = 93.1 bits (221), Expect = 2e-17 Identities = 80/303 (26%), Positives = 134/303 (44%), Gaps = 18/303 (5%) Query: 235 AAWVIVFLCLCKGVQSSGKVVYFTALFP--YVVLVILFFRGVTLPGAITGILFYLTPDFS 292 A ++++ + + KG S G L P +++ + L R +TLPGA+ G+ F L P++S Sbjct: 147 ALFMLITVWVVKGGISDGIEKANRYLMPGLFILFIALAIRSLTLPGAMEGVSFLLKPNWS 206 Query: 293 QLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLV 352 A A Q FFALS +IT +SY + + + N+ S AGLV Sbjct: 207 YF-KADTMITALGQAFFALSIGVSAMITYASYLGKDQDMFRSGHTIMWMNLLVSLLAGLV 265 Query: 353 IFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQ 412 IF + E + QG GL FIV P V ++P + +F ++++ L S Sbjct: 266 IFPAVFAFGFEPS--------QGPGLIFIVLPAVFMKMPFGTVLFAVFMLLVVFATLTSA 317 Query: 413 FALMETVTTAILDRFPNFRQKKGWV----VFIVAVFGYLGGLIFTTNS--GMYWLQLMDK 466 F+++ETV + + + R+K W+ +FIV + L I+ G L D Sbjct: 318 FSMLETVIASTIRQDERKRKKHTWLIGTAIFIVGIPSALSFGIWGEFKVFGKTIFDLWDY 377 Query: 467 YAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVF 526 + + + A+G + AWI + D + + LW R + P A++ Sbjct: 378 VISAVIMPVGALGVAVFTAWIQDKQSVLKDAGAG-STVPRAVLLLWLNRKRYLAPIAIII 436 Query: 527 ILV 529 + V Sbjct: 437 VFV 439 Score = 59.3 bits (137), Expect = 3e-07 Identities = 28/114 (24%), Positives = 51/114 (44%), Gaps = 2/114 (1%) Query: 28 NWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFG 87 +W+ + F +W+FPY NGG F + F + V+ LP+ E G Sbjct: 6 SWSSKIGFVLAAAGSAIGLGAIWKFPYTAGTNGGAVFFLLFLIFTVLVALPVQLAEFYIG 65 Query: 88 QYAALGPVAVYNKFCPLFRGLGYGMVIVSS--IVMLYYNLIIAWTIFYMTVSFS 139 + V + P + L G + VS+ I++ +Y+++ W + Y+ SF+ Sbjct: 66 RTGGQNAVDSFRALRPSTQWLWVGRMGVSACFILLSFYSVVGGWVLNYVVHSFT 119 >UniRef50_Q6AQ17 Cluster: Probable sodium-dependent transporter; n=1; Desulfotalea psychrophila|Rep: Probable sodium-dependent transporter - Desulfotalea psychrophila Length = 470 Score = 92.7 bits (220), Expect = 3e-17 Identities = 83/309 (26%), Positives = 139/309 (44%), Gaps = 25/309 (8%) Query: 231 MCLLAAWVIVFLCLCKGVQSS---GKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYL 287 +CL ++V + + G+Q V LF VV++ L+ +T PGA+ G F L Sbjct: 167 LCLTYFTILVVIAVASGIQKGIERWNKVMMPTLFGIVVVLALY--SLTTPGAVAGWKFML 224 Query: 288 TPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSF 347 PDFS+L V +A FF LS A G L+T +SY + ++ +A + + Sbjct: 225 YPDFSKLTMGGVL-EAIGHSFFTLSIAMGILVTYASYMDKKEKIFPVAIRIAFLDTVVAI 283 Query: 348 FAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTL 407 AGL IF ++ E G GL F P+ ++P + LFFV++ Sbjct: 284 GAGLAIFPIVFSFGMEPGA--------GPGLIFKTLPKAFAQMPFGNVLGTLFFVLMAFA 335 Query: 408 GLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVF--GYLGGLIFTTNS------GMY 459 L S +L+E +T +D + +KK ++ +AV+ G L ++T S GM Sbjct: 336 ALSSAISLLEVLTAFAIDE-KKYDRKKATIIMAIAVYIAGIPSALSYSTFSDITIWGGMP 394 Query: 460 WLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRII 519 L +D A+N+ + I + + +I +I + K++ +W R + Sbjct: 395 ILDGLDHMASNYMLPIGGLLIAVYAGFIVDKRILQAEITEDGAKYVKVF-RVWYFTIRYV 453 Query: 520 TPAALVFIL 528 TP LVF++ Sbjct: 454 TP-VLVFVV 461 Score = 81.4 bits (192), Expect = 7e-14 Identities = 34/120 (28%), Positives = 65/120 (54%), Gaps = 3/120 (2%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 R +W+G F N+W+FPY+ NGGGAF++ + V +++ G+PL+ E + Sbjct: 24 RNHWSGSMGFILAAVGSAVGLGNIWKFPYITGMNGGGAFVLVYLVAILLCGMPLLMAEFA 83 Query: 86 FGQYAALGPVAVYNKFCPLFRG---LGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIF 142 G+++ V + P +G +G+ + + I++ YY +I WT+FY+ + ++ F Sbjct: 84 IGRHSQKDVVGSFRDLMPKSKGWQIVGWLNLSAAFIILSYYGVIAGWTLFYLFEAVTNNF 143 >UniRef50_Q2S4H8 Cluster: Sodium-and chloride-dependent transporter; n=2; Bacteria|Rep: Sodium-and chloride-dependent transporter - Salinibacter ruber (strain DSM 13855) Length = 485 Score = 91.9 bits (218), Expect = 5e-17 Identities = 40/125 (32%), Positives = 67/125 (53%), Gaps = 2/125 (1%) Query: 20 EEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPL 79 +++E R W RF F N+WRFPY+ NGGGAFL+ + V+L++ +P Sbjct: 4 QDVELSRAQWGSRFGFLMAMLGAMVGAGNIWRFPYVTGENGGGAFLLAYFVLLLVLAIPG 63 Query: 80 MFMELSFGQYAALGPVAVYNKFCPL--FRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVS 137 + E++FG+YA G + + + GLG +++V+ +M YY ++ WT++Y S Sbjct: 64 LIAEVAFGRYAGKGVIGAFREVASSRGMVGLGVVVLVVNVALMSYYAPVVGWTLYYAVHS 123 Query: 138 FSSIF 142 F Sbjct: 124 LLFTF 128 Score = 75.8 bits (178), Expect = 3e-12 Identities = 74/310 (23%), Positives = 137/310 (44%), Gaps = 25/310 (8%) Query: 231 MCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPD 290 M L+AA I++L + +GV+ ++V + + LV + R +TLPGA G+ F + Sbjct: 157 MALVAA--ILYLGIRRGVE---RLVIYAVPGLVLALVAIMIRALTLPGAAEGLAFTFGIE 211 Query: 291 FSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYI-DSLIVAVSNIATSFFA 349 + +L Q W A Q+ F+ WG +T+ SY ++ I + + N + A Sbjct: 212 WGKLGLGQTWITALGQVLFSTGLGWGIALTVGSYLPDYDDIPIGGGVFTVIGNSSIGILA 271 Query: 350 GLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGL 409 IF ++ A +L+ GA L F+ P+V ++ LW+ILFF+ Sbjct: 272 AFAIFPIV--FAFDLDPG------SGASLTFVSLPQVFPQMAGGALWAILFFLGFFLAAF 323 Query: 410 DSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAA 469 S + E T + + R++ V+ + V +L GL + G+ L +D Sbjct: 324 TSAILITEVSVTTLSEETRLTREQT--VIGVCGVI-WLLGLGSAYSPGV--LNFLDFVFG 378 Query: 470 NWSVLIIAIGECILIAWIYGAEKFCGDIQRM--IGRQSKLWV-YLWSAMWRIITPAALVF 526 N+ + + + I W G + R+ I R + L+V +W + + + P ++ Sbjct: 379 NFGLPLSTLAIIGAIGWSMG--HLGPEKLRVLEINRNAGLYVGSIWGPVVQYVIPLVMLL 436 Query: 527 ILV-FNWIEY 535 I+ + W + Sbjct: 437 IVANYAWANF 446 >UniRef50_P45320 Cluster: Uncharacterized sodium-dependent transporter HI1690; n=36; Proteobacteria|Rep: Uncharacterized sodium-dependent transporter HI1690 - Haemophilus influenzae Length = 457 Score = 91.9 bits (218), Expect = 5e-17 Identities = 78/303 (25%), Positives = 137/303 (45%), Gaps = 23/303 (7%) Query: 238 VIVFLCLCKGVQSS--GKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLA 295 ++ ++ L KG+ V Y L ++ L+ + R VTLPGA+ GI FYL PDFS++ Sbjct: 167 IVNYIILAKGIIGGIERSVKYLMPLL-FIFLIGMVIRNVTLPGAMEGITFYLKPDFSKI- 224 Query: 296 NAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFS 355 Q++ Q+FFALS +G LITLSSY N ++I +N + AG +IF Sbjct: 225 TPQLFIFVLGQVFFALSLGFGVLITLSSYLNKEENLIHTAVITGFTNTIIAVLAGFMIFP 284 Query: 356 VIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFAL 415 + E N G L F P V + L ++I+FF +LL L + + Sbjct: 285 SLFTFGIEPNA--------GPTLVFQSLPIVFSHLWAGKFFAIIFFGLLLIAALTTSITI 336 Query: 416 METVTTAILDRFPNFRQKKGWV----VFIVAVFGYLGGLIFTTNSGMYWLQLMDKY---A 468 E + TA+ ++ R K + +F++ + G N ++ + D Y + Sbjct: 337 YEVIITALQEKLRMCRGKAIVLTLSGIFLLGNIPAILGDNLWKNVTIFGKSIFDFYDYAS 396 Query: 469 ANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFIL 528 N ++ A+G I + ++ E + + + ++ +W + + P ++ I Sbjct: 397 GNILFMLTALGCAIFVGFVLKDEA----KKELSSTKYSTFIKIWFNYVKFVVPLIILVIF 452 Query: 529 VFN 531 + N Sbjct: 453 ISN 455 Score = 60.1 bits (139), Expect = 2e-07 Identities = 30/118 (25%), Positives = 57/118 (48%), Gaps = 8/118 (6%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 +R W+ R + WRFPYL NGGGA+++ F + +++ G+P++ +E Sbjct: 7 QRQTWSSRLTYVMTVAGATVGFGATWRFPYLVGENGGGAYVLLFCIAMIVIGIPMILVEN 66 Query: 85 SFGQYAALGPVAVY-NKFCPLFRG-------LGYGMVIVSSIVMLYYNLIIAWTIFYM 134 G+ + + + +K +G LGY ++ + +M YY ++ W I Y+ Sbjct: 67 VIGRRLRVNSIDAFGDKILDKGKGISKYWKILGYMGLLGAFGIMAYYMVLGGWVISYI 124 >UniRef50_Q5WAS4 Cluster: SNF family sodium-dependent transporter; n=2; Bacillus|Rep: SNF family sodium-dependent transporter - Bacillus clausii (strain KSM-K16) Length = 443 Score = 91.5 bits (217), Expect = 6e-17 Identities = 81/314 (25%), Positives = 146/314 (46%), Gaps = 29/314 (9%) Query: 227 LGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFY 286 LG+ + + V++ + G++ + K Y L ++ L+I+ FRG++L GA+ G+ F+ Sbjct: 143 LGLVLFVFLNVVVLSFGIKNGIERANK--YLMPLL-FLFLLIIIFRGLSLEGAMEGVRFF 199 Query: 287 LTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATS 346 L PDFS++ A +A Q FF+L+ + ++T SSY + + VA N+ S Sbjct: 200 LQPDFSKI-TAPGLLEALGQSFFSLAVGFSCMVTYSSYLGEKQSLPGSAAYVAAMNVFVS 258 Query: 347 FFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLT 406 AGL IF ++ A+ + + G GL FI P + ++P L+ LF ++ Sbjct: 259 LLAGLAIFPIV--FAYGIEPA------SGPGLLFIALPAIFAQMPFGALFLSLFLLLFFF 310 Query: 407 LGLDSQFALMETVTTAILD----RFPNFRQKKGWVVFIVAVFGYL-GGLIFTTNSGMYWL 461 + S +L+E + +A N G VV + A+ L GL+ SG W Sbjct: 311 ATITSSLSLLEIIISAFTQNKGWNRRNVAMGSGVVVIVAAIPSALSAGLL----SGFAWQ 366 Query: 462 Q--LMDKYAANWSVLIIAIGECILIAWIYG----AEKFCGDIQRMIGRQSKLWVYLWSAM 515 + + D S +++ +G C+LIA G + Q G ++ + W + Sbjct: 367 EKTVFDLTDLLVSNVMLPVG-CLLIALFVGYKIKRDLLFHQFQLAAGPVGRIAPF-WLFL 424 Query: 516 WRIITPAALVFILV 529 R + PA ++ + + Sbjct: 425 MRTLVPATILLVFI 438 Score = 68.9 bits (161), Expect = 4e-10 Identities = 35/114 (30%), Positives = 53/114 (46%), Gaps = 2/114 (1%) Query: 29 WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQ 88 WT + F +WRFPYL NGGGAF + F + V GLPL+ E G+ Sbjct: 5 WTSKIGFILASAGAAIGLGALWRFPYLTGTNGGGAFFLLFILFTVFIGLPLLIAEFVIGR 64 Query: 89 YAALGPVAVYNKF--CPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSS 140 A V+ Y K + +G V+ ++M +Y ++ W + Y +SF + Sbjct: 65 GAKREAVSAYPKLVNSKAWSWIGRFGVVGCFLLMTFYAVVGGWILLYALLSFGN 118 >UniRef50_Q5DG59 Cluster: Transporter; n=1; Schistosoma japonicum|Rep: Transporter - Schistosoma japonicum (Blood fluke) Length = 282 Score = 91.1 bits (216), Expect = 8e-17 Identities = 52/192 (27%), Positives = 93/192 (48%), Gaps = 8/192 (4%) Query: 342 NIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFF 401 N + S + ++S +G+L+ + + ++ D GL FIVY V L S LW F Sbjct: 2 NASISLLNSITLYSFMGYLSQYYAIPIHQIFDGNLGLIFIVYTNVFDTLSASHLWCAFLF 61 Query: 402 VMLLTLGLDSQFALMETVTTAILDRFPNFR--QKKGWVVFIVAVF---GYLGGLIFTTNS 456 ML+TLGL S E+ TA+ D F+ KK + + +V F +L ++ Sbjct: 62 AMLVTLGLGSSIGATESFLTAVSDDCTIFKLNTKKHFRLGLVTAFLVSSFLISILTVCQG 121 Query: 457 GMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMW 516 G Y + +D YA S++++++G+C I ++YG +I + +K ++ + Sbjct: 122 GYYLVHYLDHYACGTSLILVSLGQCFAIVYVYGIYNLSENINEI---TNKAIHFITRFIL 178 Query: 517 RIITPAALVFIL 528 + P L+F+L Sbjct: 179 KFCVPLILIFML 190 >UniRef50_Q8TSA2 Cluster: Sodium/chloride-dependent transporter; n=5; cellular organisms|Rep: Sodium/chloride-dependent transporter - Methanosarcina acetivorans Length = 459 Score = 91.1 bits (216), Expect = 8e-17 Identities = 88/327 (26%), Positives = 142/327 (43%), Gaps = 33/327 (10%) Query: 222 TGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAIT 281 TGE+ MA+ ++ + + L L GV+ K + + +F ++L+IL F+ VTLPGA Sbjct: 147 TGELIFWMALVVILGFFVCSLGLQAGVERISKFM-MSGMF--LMLLILVFKAVTLPGASA 203 Query: 282 GILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVS 341 G+ FYL PDFS V+ A Q FF LS G + SY + ++L V Sbjct: 204 GLNFYLKPDFSNFNWEGVYA-AMGQAFFTLSLGIGSMAIFGSYIGKERSLTGEALDVMAL 262 Query: 342 NIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFF 401 + + AGLVIF A V G GL F+ P + ++ LW ILFF Sbjct: 263 DTLIALLAGLVIFPT----AFAFGVD----AGSGPGLVFVTLPNIFNQMIGGQLWGILFF 314 Query: 402 VMLLTLGLDSQFALMETVTTAILDRFPNFRQK----KGWVVFIVAV-----FGYLGGLIF 452 + L + + A+ E + +D + R+K G +FI ++ FG L G Sbjct: 315 MFLTFAAMTTVIAVFENIMAFTIDEWGWERKKAALRNGIGIFIFSLPCVLGFGPLSGFA- 373 Query: 453 TTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWI-----YGAEKFCGDIQRMIGRQSKL 507 G L L D +N ++ IG + + + +G F + G + Sbjct: 374 PLGEGTMVLDLEDFILSN---NLLPIGALVFVLFCTRRPGWGWNSFIEEADTGTGFKFPK 430 Query: 508 WVYLWSAMWRIITPAALVFILVFNWIE 534 W+ R + P ++ +L+ W++ Sbjct: 431 WL---KPYVRSVLPLIILVVLIKGWMD 454 Score = 65.7 bits (153), Expect = 4e-09 Identities = 34/128 (26%), Positives = 59/128 (46%), Gaps = 3/128 (2%) Query: 18 LSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGL 77 +S++ + ER + R F NVWRFP++ GG AF++ + L++ GL Sbjct: 1 MSKKKKVEREQFASRIGFLLISAGCAIGLGNVWRFPFITGKYGGAAFVLVYLAFLLLLGL 60 Query: 78 PLMFMELSFGQYAALGPVAVYNKFCPL---FRGLGYGMVIVSSIVMLYYNLIIAWTIFYM 134 P+M ME + G+ L P+ + GY +I + I+M++Y + W + Y Sbjct: 61 PIMVMEFAIGRAGHLNIAGSMRALEPVNSKWHVFGYLGIIGNVILMMFYTTVAGWGLAYF 120 Query: 135 TVSFSSIF 142 + F Sbjct: 121 YKELTGAF 128 >UniRef50_Q9KDT3 Cluster: Sodium-dependent transporter; n=2; Bacteria|Rep: Sodium-dependent transporter - Bacillus halodurans Length = 453 Score = 90.2 bits (214), Expect = 1e-16 Identities = 84/308 (27%), Positives = 139/308 (45%), Gaps = 24/308 (7%) Query: 230 AMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPY--VVLVILFFRGVTLPGAITGILFYL 287 A+ ++A IV + + KG++ S K+ L P V+L+ L +TL GA G+ F Sbjct: 154 ALFMIATIWIVAIGVKKGIERSNKI-----LMPLLGVLLIALAIYSLTLGGAKEGLAFLF 208 Query: 288 TPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSF 347 +PD+S L + V+ A Q FF LS G LIT SY S + + V+V+ + T+F Sbjct: 209 SPDWSALKDPGVYLAAISQAFFTLSLGMGALITYGSY--VSKDSRLPGAAVSVAGLDTAF 266 Query: 348 --FAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLL 405 AG++IF + A L+ S G GL F+V P++ + + P+ I FF++L Sbjct: 267 AIIAGIMIFPAV--FALGLSPS------GGPGLVFVVLPDIFDSIRLGPIVGIAFFILLG 318 Query: 406 TLGLDSQFALMETVTTAILDRFPNFRQKKGWVV-FIVAVFGYLGGLIFTTNSGMY---WL 461 L S +L+E + +F R++ + I+ + G L F + L Sbjct: 319 AAALSSAVSLLEVPVAYFMRKFDWSRKQAAITLGVIITLLGIPSSLSFGVLGEVTIIPGL 378 Query: 462 QLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITP 521 + D S + + +G I+ +I K D +W LW R I P Sbjct: 379 NIFDSVDFIASSVFLPLGGMIIALFIGWGWK-TSDALAESDLTDSVWGKLWILSLRFIAP 437 Query: 522 AALVFILV 529 A++ + + Sbjct: 438 IAILIVFL 445 Score = 67.3 bits (157), Expect = 1e-09 Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 2/111 (1%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 R W R F N+WRF Y+ NGG AFL+ + + + G+P++ E + Sbjct: 9 REQWASRLGFILAAMGSAVGLGNIWRFSYVTGENGGAAFLLVYLGFIALIGIPIVLAEFT 68 Query: 86 FGQYAALGPVAVYNKFCP--LFRGLGYGMVIVSSIVMLYYNLIIAWTIFYM 134 G+ A V + K P ++ G V +++ +Y +I W +FY+ Sbjct: 69 IGRRAQSDAVGSFEKLAPGKPWKVAGLMGVAAGFLILSFYGVIAGWILFYL 119 >UniRef50_A6TKT9 Cluster: Transporter; n=2; Clostridiaceae|Rep: Transporter - Alkaliphilus metalliredigens QYMF Length = 499 Score = 89.8 bits (213), Expect = 2e-16 Identities = 62/263 (23%), Positives = 118/263 (44%), Gaps = 13/263 (4%) Query: 231 MCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPD 290 + +L A I++ + G++ + K++ T +V+L+ R +TLPGA+ G+ + TP+ Sbjct: 151 LSMLIAGFIIYKGVKGGIEKASKIMIPTL---FVLLIAAVIRALTLPGALQGLEYLFTPN 207 Query: 291 FSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAG 350 L N +W +A Q ++ WG +IT S Y K + + +I+ + + A Sbjct: 208 LHMLKNPTIWLEAFTQAAWSTGAGWGFIITYSVYTKQKEDVAGNCMIMGFGDNIGALIAA 267 Query: 351 LVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLD 410 + + I L+ + + + G+ FI ++ T +P + +FF+ + L Sbjct: 268 MTVLPAIYALSPTPEFAAEALSSGNTGITFIYLAQLFTTMPAGQFLAAIFFLAMAISALS 327 Query: 411 SQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAAN 470 S ++E ++D F +KK +VA G+L G+ Y L +D Sbjct: 328 SLLPMIEVGVRNLMDM--GFDRKKATASIVVA--GFLLGI-----PSAYSLHFLDNQDWV 378 Query: 471 WSVLIIAIGECILIAWI-YGAEK 492 W V ++ G + A YG E+ Sbjct: 379 WGVGLLVSGLFVAFALAKYGLER 401 Score = 78.6 bits (185), Expect = 5e-13 Identities = 34/115 (29%), Positives = 58/115 (50%), Gaps = 1/115 (0%) Query: 29 WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQ 88 W R F N+WRFP + NGGG F+I +T+ L + +PL+ E+ G+ Sbjct: 8 WGSRIGFIAAAIGMAIGTGNIWRFPRVAAANGGGPFVIAWTIALFVWAIPLLMGEMVMGR 67 Query: 89 YAALGPVAVYNKFC-PLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIF 142 LG + + F + +G + +V +M YY++++ WT+ Y T++ S F Sbjct: 68 KTGLGTIGAFRDFVGKKYTWMGTWIAVVCLGIMFYYSVVMGWTMKYFTLAVSGAF 122 >UniRef50_Q8F511 Cluster: Transporter; n=4; Leptospira|Rep: Transporter - Leptospira interrogans Length = 511 Score = 89.4 bits (212), Expect = 3e-16 Identities = 82/338 (24%), Positives = 145/338 (42%), Gaps = 14/338 (4%) Query: 204 AEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPY 263 A Y+ + +G + +I C + + +VF + KG+++ K+ L Sbjct: 126 AGNYYLDLTGARHNGDAISSKIFYATITCFILNFALVFRGISKGIETFAKIAVPLMLVSS 185 Query: 264 VVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSS 323 ++++I R +TL G+ PD+S L ++VW AA Q+FF LS +G + SS Sbjct: 186 IIILI---RVLTLDNIDIGLGKMWNPDWSALLKSEVWIAAAGQVFFTLSAGFGIALVFSS 242 Query: 324 YNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGA-GLAFIV 382 Y K N+ + S+ A N G +I + FL L S++ D G G+ FI Sbjct: 243 YLKRDNDVVLSSISAASLNEFVEVAVGGMITIPVAFLF--LGSSIN---DFGMFGMGFIA 297 Query: 383 YPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVA 442 P V + +P + ++F +L + S +++ + + F R+ ++F+ Sbjct: 298 LPSVFSLMPGGQWFGAIWFFVLFLAAITSSVTMLQPGIIFLEESFGLKRKTSCLILFLFT 357 Query: 443 VFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIG 502 L I N L+L D + + I+A + L W GA+K D G Sbjct: 358 --ASLSFPILYFNQNFEALELADFWIGTILIFILASIQIFLFGWKIGAKKGLEDGNE--G 413 Query: 503 RQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASY 540 +L + W + + ITP L+ I + I+ P + Sbjct: 414 SHLELPKFFWFVI-QYITPTFLLVIFIAFLIQNLPGHF 450 Score = 46.4 bits (105), Expect = 0.002 Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 5/91 (5%) Query: 48 NVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAA-LGPVA--VYNKFCPL 104 N RFP NGGGAF++P+ + ++ G+P+ E G+ G A ++ F Sbjct: 10 NFIRFPGQAVANGGGAFMVPYIISFILVGIPVCITEWIMGRMGGRTGHSAPFLFKSFLSG 69 Query: 105 F--RGLGYGMVIVSSIVMLYYNLIIAWTIFY 133 F R +G + + ++ +YY I AW + Y Sbjct: 70 FPLRIVGAIGITIPILIYVYYVFIEAWCLAY 100 >UniRef50_UPI0000D57368 Cluster: PREDICTED: similar to CG8485-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG8485-PA, isoform A - Tribolium castaneum Length = 976 Score = 88.6 bits (210), Expect = 4e-16 Identities = 66/254 (25%), Positives = 109/254 (42%), Gaps = 36/254 (14%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 R +W R + N + FP Y GG F IP+TV+ + G PL ++ S Sbjct: 76 RLHWRNRITYVIGFMAFTLSLNNAYHFPMNIYRYGGN-FFIPYTVVTIFVGYPLHVLQTS 134 Query: 86 FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQL 145 GQY+ G + ++ + P G+G MV+ +V LY+N+ A+ + Y F + L Sbjct: 135 MGQYSQRGVLWMW-ECAPFCCGVGVAMVLACFLVALYHNIFAAYALVYFAHCFHLV---L 190 Query: 146 PWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAE 205 PW +C E+AD C S+ +S NI ++ Sbjct: 191 PWT---------YCSEVEDADA----------HACAPPSWYISQNINL---------SSQ 222 Query: 206 EYFTNQVLGL---SSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFP 262 EYF N V+ S + G I+ + + L +WV+ ++ + + V+S GK+ F + Sbjct: 223 EYFYNVVVDTNDKSHYLWSLGSIKWWLVLSLAFSWVVCYIAVLRSVRSIGKICIFIIILS 282 Query: 263 YVVLVILFFRGVTL 276 Y L+ L + L Sbjct: 283 YFTLLTLIIVALQL 296 >UniRef50_A5ZSS6 Cluster: Transporter; n=5; Clostridiales|Rep: Transporter - Ruminococcus obeum ATCC 29174 Length = 465 Score = 88.6 bits (210), Expect = 4e-16 Identities = 82/298 (27%), Positives = 136/298 (45%), Gaps = 18/298 (6%) Query: 239 IVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQ 298 I++ + GV+ K + +F +V+ + VT PGA+ G+ ++L P+ + Sbjct: 167 IIYAGVRNGVERVSKFMMPVLVFLSIVITVY---SVTRPGALEGVKYFLIPNPKNFSWMT 223 Query: 299 VWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIF-SVI 357 V A Q+F++LS A G L+T SY K + + V + + A + AGL+I +V Sbjct: 224 VVA-AMGQMFYSLSIAMGILVTFGSYMKKDVSIESSTTNVEIFDTAIAIMAGLMIIPAVF 282 Query: 358 GFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALME 417 F + N + G L FI P+V + + ILFFV++L L S AL E Sbjct: 283 AFSGGDPNT-----LQAGPALMFITIPKVFASMGLGTPIGILFFVLVLCAALTSSIALTE 337 Query: 418 TVTTAILDRFPNFRQKKGWVV-FIVAVFGYL-----GGLIFTTNSGMYWLQLMDKYAANW 471 + + D RQK VV I+ V G L G L GM +L D + Sbjct: 338 SAVSTFQDELKWCRQKSTLVVGAIMIVLGSLSSLGYGPLACVKIIGMQFLDFFDFLTNSV 397 Query: 472 SVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILV 529 + I AI C+LI+ + G +K ++ ++G + +++ M + + P IL+ Sbjct: 398 MMPIAAIATCLLISRVIGLKKIEDEV--VLGEGTFKRKKIFNFMIKYLCPIFAAIILL 453 Score = 68.1 bits (159), Expect = 7e-10 Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 4/123 (3%) Query: 15 KAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVI 74 K E+ ER ++G+ F N+WRFPYL GGG FL+ + ++ + Sbjct: 5 KGNFMEQHHHERSTFSGKLGFVLSAAGASVGLGNIWRFPYLAAKYGGGIFLLIYIILAMT 64 Query: 75 AGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYG---MVIVSSIVMLYYNLIIAWTI 131 G ++ E + G+ PV + KF + L +G I+ +++ YY++I W I Sbjct: 65 FGYSMIIAETALGRMTKKSPVGAFGKF-GKSKWLSFGGWINAIIPILIVPYYSVIGGWVI 123 Query: 132 FYM 134 Y+ Sbjct: 124 KYL 126 >UniRef50_Q3V0K1 Cluster: Transporter; n=10; Eutheria|Rep: Transporter - Mus musculus (Mouse) Length = 423 Score = 87.8 bits (208), Expect = 8e-16 Identities = 44/179 (24%), Positives = 93/179 (51%), Gaps = 5/179 (2%) Query: 374 QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK 433 +G GL+++ + + ++ P S W+I+FF+ L +GL + L+E + + F + Sbjct: 97 EGPGLSYVAFSQAISLFPGSSFWAIIFFMSLAIMGLGTMLTLLEGIVLPLQKSISTFAKH 156 Query: 434 KGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKF 493 V +V + G+LG L+F++ G Y + L D ++II + + + +AW+YG ++F Sbjct: 157 PNLVQVLVCLGGFLGSLVFSSRPGSYVVFLFDDLLVPMVLIIIVVIQNLSLAWLYGIKRF 216 Query: 494 CGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAV 552 ++ +G S +W ++ +W +T L+ +L ++ + +YV W D++ Sbjct: 217 RAEVFGQLG--SLVW-SPFTFLWSYVTLPTLLVLLTIYFLNLYYSGSPYYV--SWNDSM 270 >UniRef50_Q1MR94 Cluster: Probable sodium-dependent transporter; n=1; Lawsonia intracellularis PHE/MN1-00|Rep: Probable sodium-dependent transporter - Lawsonia intracellularis (strain PHE/MN1-00) Length = 455 Score = 87.4 bits (207), Expect = 1e-15 Identities = 76/316 (24%), Positives = 138/316 (43%), Gaps = 23/316 (7%) Query: 233 LLAAWVIVFLCLCKGVQSSGKVVY--FTALFP--YVVLVILFFRGVTLPGAITGILFYLT 288 LL W+++ L ++ + K + T L P +++L+I+ R +TLP AI G+ F Sbjct: 147 LLWQWLVIILVATIVLRGASKGIEKAATILMPILFILLIIICIRSITLPNAIEGLRFLFM 206 Query: 289 PDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFF 348 PDFS++ + +V A FF LS G ++T SY K N + V + ++ S Sbjct: 207 PDFSKI-DGRVILLAMGLAFFKLSIGMGVMLTYGSYFKDDVNIPYMATKVMLLDLVVSLL 265 Query: 349 AGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLG 408 +G+ IF V+ E G GL FI P V +P +++ FF++ Sbjct: 266 SGIAIFPVVFSFGFE--------PSSGPGLLFITIPAVFDSMPAGQIFTGAFFILAAVAS 317 Query: 409 LDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTN-------SGMYWL 461 + +L ET +D F N +K ++ ++ + + + N GM + Sbjct: 318 TGAMLSLFETPVAWAIDTF-NLSRKNTTIIIMLFFIAFGAPVALSENILKHITIFGMNFF 376 Query: 462 QLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITP 521 QL D ++N + + CI + +++ + I ++ + L R +TP Sbjct: 377 QLYDFLSSNILMPLGGFFLCIFVGYVWNKQMVMHAISNGGTLHNQGLIKLLLFQCRYVTP 436 Query: 522 AALVFILV--FNWIEY 535 ++ I++ FN Y Sbjct: 437 VIILIIMLHGFNLFAY 452 Score = 58.0 bits (134), Expect = 7e-07 Identities = 26/111 (23%), Positives = 52/111 (46%), Gaps = 1/111 (0%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 +R ++T + N+W+FP + NGG +FL+ + + ++AGLP+M E+ Sbjct: 6 KRDSFTSKIGILAATLGSAVGLGNIWKFPTVIGQNGGASFLLIYIIATIVAGLPIMIAEI 65 Query: 85 SFGQYAALGPVAVYNKFCPLFRGL-GYGMVIVSSIVMLYYNLIIAWTIFYM 134 + G+ V + K + L G+ + + V+ +Y + W Y+ Sbjct: 66 AIGRSTRANAVEGFKKLSSGYWWLVGFAGTLSTVFVLGFYTEVAGWIYAYI 116 >UniRef50_Q6GC30 Cluster: Transporter; n=16; Staphylococcus|Rep: Transporter - Staphylococcus aureus (strain MSSA476) Length = 446 Score = 86.2 bits (204), Expect = 2e-15 Identities = 63/218 (28%), Positives = 109/218 (50%), Gaps = 13/218 (5%) Query: 227 LGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFY 286 LG + + A +IV L + KG++ + KV+ LF +++++++ + +TL GA+ G+ F Sbjct: 149 LGQGIFIFATMIIVMLGVEKGLEKASKVM-MPLLFVFLIIIVI--KSLTLDGALEGVKFI 205 Query: 287 LTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATS 346 L P S++ + A Q FF LS G+IT +SY ++ + V NI S Sbjct: 206 LQPRVSEITADGILF-ALGQSFFTLSLGTTGMITYASYASKDMTIKSSAISIVVMNIFVS 264 Query: 347 FFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLT 406 AGL IF + +E +G GL F V P V +++ + L+ + F V+ L Sbjct: 265 VLAGLAIFPALHSFGYE--------PQEGPGLLFKVLPMVFSQMHLGTLFYLGFLVLFLF 316 Query: 407 LGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVF 444 L S +L+E + + + N ++KK V+ + VF Sbjct: 317 AALTSSISLLE-LNVSNFTKNDNTKRKKVAVIGSILVF 353 Score = 58.8 bits (136), Expect = 4e-07 Identities = 28/112 (25%), Positives = 49/112 (43%), Gaps = 2/112 (1%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 ++ W F +W+FPY+ GGGAFL F + + GLPL+ ME Sbjct: 5 QQSQWKSSTGFILASAGSAIGLGAMWKFPYMAGIYGGGAFLAMFLIFTIFVGLPLLIMEF 64 Query: 85 SFGQYAALGPVAVYNKFC--PLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYM 134 + G+ +Y+K +G+ + I+ +Y++I W + Y+ Sbjct: 65 TVGKMGRTYTTQIYSKLTGKKWLNIIGWNGNLAVFILFGFYSVIGGWIVIYI 116 >UniRef50_A3HYF8 Cluster: Sodium-and chloride-dependent transporter; n=1; Algoriphagus sp. PR1|Rep: Sodium-and chloride-dependent transporter - Algoriphagus sp. PR1 Length = 461 Score = 86.2 bits (204), Expect = 2e-15 Identities = 60/209 (28%), Positives = 102/209 (48%), Gaps = 9/209 (4%) Query: 237 WVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRG--VTLPGAITGILFYLTPDFSQL 294 ++++ + + G S G L P + ++I+F G VTL GA GI +YLTPDF+++ Sbjct: 148 FIMMTILIVLGGVSGGIEKASKFLMPVLFIIIIFIAGRSVTLEGAQAGIEYYLTPDFAKI 207 Query: 295 ANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIF 354 N V A Q FF++S WG +IT SY +N + +A + + + GL++F Sbjct: 208 -NPTVILQALGQAFFSMSVGWGLMITFGSYLPKKSNIIQSAGWIAGMDTSVALLGGLMVF 266 Query: 355 SVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFA 414 + L + + G L F V P+V +P + LFF++L+ L S + Sbjct: 267 PALFALLPGKDPAA------GPALVFDVLPKVFDAMPGGNIIGGLFFILLMVAALTSTIS 320 Query: 415 LMETVTTAILDRFPNFRQKKGWVVFIVAV 443 ++E ++D R++ W V I A+ Sbjct: 321 MLEVPVAYLIDDRKWGRKRSTWTVGIAAM 349 Score = 79.0 bits (186), Expect = 4e-13 Identities = 39/122 (31%), Positives = 60/122 (49%), Gaps = 8/122 (6%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 ERG W F N+WRFPYL NGGGAF+ + + +++ LPL+F E+ Sbjct: 9 ERGQWGSSLGFIMAAAGSAVGLGNIWRFPYLVGENGGGAFVFVYIICVLLIALPLLFNEI 68 Query: 85 SFGQYAALGPVAVY-----NKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFS 139 + G+ + P+ NKF ++ G V+V V YY++I WT+ Y+ Sbjct: 69 ALGRRSGKNPIGAIRETGGNKF---WQSAGVLCVLVCFFVFSYYSVIAGWTVGYIFTEII 125 Query: 140 SI 141 +I Sbjct: 126 NI 127 >UniRef50_Q9KG95 Cluster: Sodium-dependent transporter; n=34; Bacillales|Rep: Sodium-dependent transporter - Bacillus halodurans Length = 457 Score = 85.8 bits (203), Expect = 3e-15 Identities = 90/355 (25%), Positives = 156/355 (43%), Gaps = 32/355 (9%) Query: 207 YFTNQVLGLSSGIEET--GEIRLG------MAMCLLAAWV-IVFLCLCKGVQSS---GKV 254 YF + G SG++E GEI +A+ A++ IV + +GV+ V Sbjct: 111 YFLKAITGQLSGLDEGRYGEIFAETISNPILAISSQFAFLAIVMYVVSRGVKKGIERASV 170 Query: 255 VYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPA 314 + ALF V+ + + RG+TL GA G+ F+L PDFS + + + A Q FFALS Sbjct: 171 IMMPALF--VLFLAIVIRGLTLDGATEGLAFFLVPDFSTITSETLLY-AMGQSFFALSVG 227 Query: 315 WGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQ 374 ++T SSY + +L + + +F AG+ IF + S D+ Sbjct: 228 VSVMVTYSSYLSRDESIVQSALSIVMLTFVVAFLAGVAIFPAV--------FSFGMSPDE 279 Query: 375 GAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKK 434 G L F V P V ++P + + F ++ L L S F+++E V AI + R K Sbjct: 280 GPVLLFNVLPSVFDQMPYGAFFLVTFLLLFLFATLTSAFSMLEVVVAAITKGDVSQRPKV 339 Query: 435 GWVV-FIVAVFGYLGGLIFTTNSG--MYWLQLMDKYAANWSVLIIAIGECILIAWI---Y 488 W++ + G L + S ++ + D S +++ IG ++ ++ Sbjct: 340 TWLIGLAIFAVGIPSALSYGVWSDVLLFGRTVFDTADFLVSNILMPIGALLIAIFVPLKI 399 Query: 489 GAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITP--AALVFILVFNWIEYKPASYG 541 E+ +I+ +L+ +W + R + P A+VF+ V + + A G Sbjct: 400 SKERLYEEIKAGASIGKRLFA-IWFILIRYVAPIVIAIVFLDVIGALSFISAVAG 453 Score = 59.7 bits (138), Expect = 2e-07 Identities = 27/107 (25%), Positives = 49/107 (45%), Gaps = 2/107 (1%) Query: 29 WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQ 88 W+ + F +W+FPY+ +GGGAF + F + ++ GLPL+ E G+ Sbjct: 5 WSSKLAFILAAAGSAVGLGAIWKFPYVTGTSGGGAFFLIFILFTLLIGLPLLIGEFVIGR 64 Query: 89 YAALGPVAVYNKFCP--LFRGLGYGMVIVSSIVMLYYNLIIAWTIFY 133 + Y P + G+G + +++ +Y++I W I Y Sbjct: 65 STQKNAIESYRAIAPNSSWGGVGKLGIFTCFLLLSFYSVIGGWIIIY 111 >UniRef50_Q8A1L9 Cluster: Na+-dependent transporter; n=8; Bacteroidales|Rep: Na+-dependent transporter - Bacteroides thetaiotaomicron Length = 456 Score = 85.4 bits (202), Expect = 4e-15 Identities = 79/267 (29%), Positives = 126/267 (47%), Gaps = 21/267 (7%) Query: 227 LGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFY 286 L + + LL I+ + KG++ S K++ T +++++IL VTLPGA GI F Sbjct: 148 LWLVLFLLVTHFIIVKGVEKGIEKSSKIMMPTL---FIIILILVICSVTLPGAGAGIEFL 204 Query: 287 LTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATS 346 L PDFS++ + V+ A Q FF+LS G L T +SY N + V + + + Sbjct: 205 LKPDFSKV-DGNVFLSAMGQAFFSLSLGMGCLCTYASYFSKETNLTKTAFSVGIIDTFVA 263 Query: 347 FFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTR----LPI-SPLWSILFF 401 AG +IF SV D G L FI P V + +PI + ++S++F+ Sbjct: 264 VLAGFIIFPAA--------FSVGIQPDAGPSLIFITLPNVFQQAFSGVPILAYIFSVMFY 315 Query: 402 VMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVF-GYLGGLIFTTNSG--M 458 V+L L S +L E VT + + F R K +V +F G L L G + Sbjct: 316 VLLAMAALTSTISLHEVVTAYLHEEFNFTRGKAARLVTGGCIFLGILCSLSLGVMKGFTI 375 Query: 459 YWLQLMDKYAANWSVLIIAIGE-CILI 484 + L + D + + +++ +G CI I Sbjct: 376 FGLGIFDLFDFVTAKIMLTLGGLCISI 402 Score = 66.9 bits (156), Expect = 2e-09 Identities = 30/120 (25%), Positives = 59/120 (49%), Gaps = 2/120 (1%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 +R N+ + N+WRFPY N+GG AF++ + + + GLP++ E Sbjct: 5 DRANFGSKLGVILASAGSAVGLGNIWRFPYETGNHGGAAFILIYLGCVFLLGLPILIAEF 64 Query: 85 SFGQYAALGPVAVYNKFCP--LFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIF 142 G+ + Y K P +R +G V+ + +++ YY+++ WT+ Y+ + ++ F Sbjct: 65 LIGRRSRANTAGAYQKLAPGTHWRWVGRMGVLAAFLILSYYSVVAGWTLEYVYEALTNGF 124 >UniRef50_A7HNE0 Cluster: Sodium:neurotransmitter symporter; n=1; Fervidobacterium nodosum Rt17-B1|Rep: Sodium:neurotransmitter symporter - Fervidobacterium nodosum Rt17-B1 Length = 518 Score = 85.4 bits (202), Expect = 4e-15 Identities = 72/290 (24%), Positives = 133/290 (45%), Gaps = 23/290 (7%) Query: 263 YVVLVILFFRGVTLPGAIT-------GILFYLTPDFSQLANAQVWGDAAVQIFFALSPAW 315 Y+ +IL R +TL + G+ F +P +++L N AA QIFF LS Sbjct: 190 YIFAIILLVRALTLGSPVNPEWNPIKGLDFLWSPRWNEL-NWSATLAAAGQIFFTLSLGM 248 Query: 316 GGLITLSSYNKFSNNCYIDSLIVAVSN-IATSFFAGLVIFSV-IGFLAHELNVSVDRVVD 373 G + +SY + ++ ++ A N A AG ++ + FL E + Sbjct: 249 GIIQNYASYMRDEDDIVTSAVATASLNEFAEVILAGTIVIPIAFTFLGAE-------GLK 301 Query: 374 QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK 433 G GL+FI P V + ++ +F++L G+ S A+ +T + + F R+K Sbjct: 302 SGVGLSFIALPNVFRNMAGGQIFGTFWFLLLFFAGITSSIAMFNYLTAFLEEEFGVERKK 361 Query: 434 KGWVVFIVAVFGYLGGL---IFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGA 490 VF++ + G L I T + + +L +D + + ++++ + E I W++ A Sbjct: 362 GSLFVFLMYIIGGLPVALEPILTKTADLMYLTELDNWVGTYFLVLLGLIEVIAAVWLFKA 421 Query: 491 EKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASY 540 K +I + G K+ ++ + + ITPA ++ +LVF+ I+Y Y Sbjct: 422 -KGLEEINK--GSYWKIPMWFYKLIMSFITPAFIIILLVFSTIDYAKNGY 468 Score = 70.1 bits (164), Expect = 2e-10 Identities = 39/124 (31%), Positives = 62/124 (50%), Gaps = 16/124 (12%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 +R +W + N WRFPY NGGGAF+IP+ + + G+PL+ +E Sbjct: 3 KREHWGSKIGLILAMAGNAIGLGNFWRFPYQAAKNGGGAFMIPYFIAFLFMGIPLLIIEW 62 Query: 85 SFGQY------AALGPV-------AVYNKFCPLFRGLGYGMVIVSSIVML--YYNLIIAW 129 + G+Y LGP+ +V +KF + L G + +S +++L YYN +I W Sbjct: 63 AQGRYGGKYGHGTLGPMIYLQAKESVGHKFAKVLGALA-GAIALSVVILLNSYYNHVIGW 121 Query: 130 TIFY 133 T+ Y Sbjct: 122 TLGY 125 >UniRef50_UPI0000DB7B68 Cluster: PREDICTED: similar to CG8291-PA, isoform A, partial; n=1; Apis mellifera|Rep: PREDICTED: similar to CG8291-PA, isoform A, partial - Apis mellifera Length = 835 Score = 85.0 bits (201), Expect = 5e-15 Identities = 109/436 (25%), Positives = 179/436 (41%), Gaps = 62/436 (14%) Query: 225 IRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFR--GVTLPGAITG 282 ++ +A L W+IVF+ L KG++S GKVVY L P ++L + G+T PG+I Sbjct: 151 LKFQLAFNLAVVWMIVFVSLSKGLKSYGKVVYVFTLVPVFGTLVLCTKLLGLTPPGSIHQ 210 Query: 283 ILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSN 342 LF T N + W A++++F + ++++NK + D+ +V V Sbjct: 211 -LFPATVWTEFFINGKSWLAASIEVFLTWGLFGAAAMQIAAHNKHKHLLQRDTSLVIVLT 269 Query: 343 IATSFFAG---------------LVIFSVIG-------FLAHELNVSVDRVVDQGAG--- 377 IA A + I S G F+AH + +RV GA Sbjct: 270 IAVLLLAAFLANTCVQVLRHHGYIYIPSSFGYNSTPERFMAHTSFIVGERVTRPGADFSI 329 Query: 378 --------LAFIVYPEVVTRL---PISPLWSILFFVMLLTLGLDSQFALMETVTTAILDR 426 L+ + P + L +SP W+ILF+ +L+ G+ Q A+ V T I+ Sbjct: 330 ESGYQVLRLSTELVPATLALLGTEQVSPFWAILFYFILILFGIAQQLAIWHCVITGIM-- 387 Query: 427 FPNFRQKKGW---VVFIVAVFGYLGGLIFTTNSGMYWLQLMD-KYAANWSVLIIAIGECI 482 N + K W V F Y+ GL T G++ + +D W ++I+ + + Sbjct: 388 AINTKMMKLWETTVTFFSCACAYILGLPMATELGIHVVYYLDYTIGGTWWIIILYLVQVG 447 Query: 483 LIAWIYG----AEKFCGDIQRMIGRQSKLWV-YLWSAMWRIITPAALVF--ILVFNWIEY 535 + + G E ++ GR + W L S W +I P L+ I +F + Sbjct: 448 AVFAVRGRPHSGEAVVAELFPPTGRCLRHWAGPLLSFTWNVILPVILMVLSITIFKNAGF 507 Query: 536 KPA-SYGHYV---YPMWADAVGWTXXXXXXXXXXXXXXDQIC----SGPDDLTIMEKARV 587 + SY V + +WA +G T Q C +GP D I ++ ++ Sbjct: 508 RELYSYRRTVKEYWTIWAKQLGATIQLIPILTIPAVAIIQTCRYLNNGPPD--IFDRIQL 565 Query: 588 LARPTEEWGQAGSTAT 603 L RP+ E T T Sbjct: 566 LYRPSLESDDPRDTQT 581 Score = 54.4 bits (125), Expect = 9e-06 Identities = 30/126 (23%), Positives = 56/126 (44%), Gaps = 2/126 (1%) Query: 10 DEEKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFT 69 D + + +E G W N+ RF L G F++ F Sbjct: 9 DRNEDRGEDEDEDANPLGKWPHALSPALACLSCTLGLFNISRFSILSIQFGAN-FIVQFL 67 Query: 70 VMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAW 129 ++ +I G+PL+ + + GQ A G V ++ K P+F+G+G ++I + + +Y + I+W Sbjct: 68 ILSLILGIPLLTLHVCLGQRLAAGSVNMW-KISPVFQGVGIALLIAQAFIGIYSVVGISW 126 Query: 130 TIFYMT 135 Y + Sbjct: 127 MFVYFS 132 >UniRef50_Q8D8U8 Cluster: Na+-dependent transporter of the SNF family; n=18; Bacteria|Rep: Na+-dependent transporter of the SNF family - Vibrio vulnificus Length = 475 Score = 84.6 bits (200), Expect = 7e-15 Identities = 90/335 (26%), Positives = 152/335 (45%), Gaps = 32/335 (9%) Query: 209 TNQVLGLSSG--IEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVL 266 T +G S G I + + L M + LL VIV + G++ +GKV+ LF ++L Sbjct: 127 TPDTIGSSFGAFISDPVQPLLWMGVYLLLNIVIVMRGVSGGIEKAGKVL-MPLLF--IIL 183 Query: 267 VILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNK 326 +I+ +G+ LPGA+ G+ F PDFS++ ++ V A Q FF+LS G ++T SY K Sbjct: 184 IIVSVKGLMLPGAMAGLEFLFMPDFSKV-DSNVVLAALGQAFFSLSLGMGCMMTYGSYLK 242 Query: 327 FSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEV 386 N + +V + + AG+ +F + E G GL F+V P++ Sbjct: 243 KQENLVQTTGMVTAMDTGVAILAGVAMFPAMFAFGME--------PAAGPGLVFVVVPQL 294 Query: 387 VTRL--PISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQ----KKGWVVFI 440 + + I + ++LFF+ L L S +L+E V + ++D R V+ Sbjct: 295 FSEMGGVIGLVLALLFFIGLTVAALTSSVSLLEVVVSYLIDEKGMKRSTAVISSSIVMAS 354 Query: 441 VAVF-----GYLGGLIFTTNSGMYWLQLMDK-YAANWSVLIIAIGECILIAWIYGAEKFC 494 + +F G +G +F T + + L DK + A +L+ CI W E Sbjct: 355 LCIFASLSLGGVGPKLFDTGAFDIFDLLTDKIFLAVGGMLV-----CIFAGWRLSREDLE 409 Query: 495 GDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILV 529 +I G+ S +W + + I P A+ + V Sbjct: 410 KEITN-DGKVSFPLFGVWYNLVKYIIPVAIAIVAV 443 Score = 56.4 bits (130), Expect = 2e-06 Identities = 25/109 (22%), Positives = 45/109 (41%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 R W + F N+W+FPY +GGGAF+ + ++ G +M E + Sbjct: 9 RDTWGSKLGFVMAAAGSAVGLGNIWKFPYTAGESGGGAFVAIYLFFVIFIGFSVMLTEFA 68 Query: 86 FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYM 134 G+ L V + + G V ++M +Y ++ W + Y+ Sbjct: 69 IGRKTGLSAVGAFKSTDRRWTFTGVLGVFSGLLIMGFYPVVGGWALAYI 117 >UniRef50_Q81S42 Cluster: Sodium-dependent transporter; n=13; Bacillaceae|Rep: Sodium-dependent transporter - Bacillus anthracis Length = 445 Score = 84.6 bits (200), Expect = 7e-15 Identities = 80/311 (25%), Positives = 145/311 (46%), Gaps = 20/311 (6%) Query: 227 LGMAMCLLAAWVIVFLCLCKGVQSSGKVV--YFTALFPYVVLVILFFRGVTLPGAITGIL 284 L + LL + +F+ + KGVQ+ + V YF +V+ +L R +TL GA G+ Sbjct: 141 LAVGSQLLFILITIFI-VSKGVQNGVEKVNKYFMPAL-FVLFFVLIVRALTLDGAGEGVR 198 Query: 285 FYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIA 344 F+L PDFS + ++V A Q FF+LS ++T SSY + + + + Sbjct: 199 FFLQPDFSNV-TSEVILYAMGQSFFSLSVGVAVMVTYSSYLPKEESLPRSAFSIVGLTLV 257 Query: 345 TSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVML 404 + AGL IF V+ A L S QG GL FIV P + +++ ++ ++F ++ Sbjct: 258 ITLLAGLAIFPVV--FAFGLEPS------QGPGLLFIVLPAIFSKMAFGKVFFVIFLLLF 309 Query: 405 LTLGLDSQFALMETVTTAILDRFPNFRQKKGWVV-FIVAVFGYLGGLIFTTNSGMYWLQL 463 + S +++E ++ + R+K +V ++ V G L F S + Sbjct: 310 FFATITSAISMLEISVASLTSKGKGKREKMALIVGLLIFVVGVPSALSFGILSDLKIFGK 369 Query: 464 MDKYAANWSVLIIAIGECILIAWIYGAEKFCGDI-QRMIG----RQSKLWVYLWSAMWRI 518 A+++V + + +L+ I+ K D+ + +G + KL+V LW + R Sbjct: 370 TVFDLADYAVSNVLMPLGVLLVSIFVPLKMKKDVLMKELGVSKNKGYKLFV-LWLFLLRF 428 Query: 519 ITPAALVFILV 529 I P A++ + + Sbjct: 429 IAPIAIIIVFL 439 Score = 62.9 bits (146), Expect = 3e-08 Identities = 29/108 (26%), Positives = 50/108 (46%), Gaps = 2/108 (1%) Query: 29 WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQ 88 WT + F +W+FPY+ GGGAF + F ++ GLPL+ E G+ Sbjct: 6 WTSKLGFVLAAAGSAIGLGAIWKFPYMAGIGGGGAFFLIFIGFTLLIGLPLLLAEFVIGR 65 Query: 89 YAALGPVAVYNKFCP--LFRGLGYGMVIVSSIVMLYYNLIIAWTIFYM 134 V Y + P L+ LG ++ I++ +Y+++ W + Y+ Sbjct: 66 STQKEAVDAYREIAPKTLWPWLGKLGIVTCFILLSFYSVVGGWILLYL 113 >UniRef50_Q73R42 Cluster: Sodium-dependent transporter, putative; n=6; Bacteria|Rep: Sodium-dependent transporter, putative - Treponema denticola Length = 441 Score = 84.6 bits (200), Expect = 7e-15 Identities = 66/254 (25%), Positives = 112/254 (44%), Gaps = 19/254 (7%) Query: 247 GVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQ 306 G++ K++ T + + +IL R TLP A+ G F D+S LAN + W A Q Sbjct: 170 GIEKINKIMMPTF---FTLFIILAIRVATLPKALDGYKFLFKTDWSALANIKTWVFALGQ 226 Query: 307 IFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNV 366 FF+LS A G + SY S + + A+ + + A LVI + A+ L Sbjct: 227 AFFSLSLAGSGTVVYGSYLNDSEDARTSAKYTAIFDTLAAMIAALVIIPAV--FAYGLEP 284 Query: 367 SVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDR 426 + G L FI P + +P L+SI+FF+ +L G+ S L ET + + Sbjct: 285 AA------GPPLMFITMPMIFKEMPAGTLFSIIFFIAVLFAGITSLINLYETPVELMQQK 338 Query: 427 FPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGM-YWLQLMDKYAANWSVLIIAIGECILIA 485 F N +K + IV G+ GL+ + + W+ ++ Y L+ ++ Sbjct: 339 F-NLSRKA--ALAIVLGLGFAVGLVVEDGNVLGTWMDVISIYIIPLGALLAG----VMFF 391 Query: 486 WIYGAEKFCGDIQR 499 W+ G + ++ + Sbjct: 392 WVAGKDFVLNEVSK 405 Score = 54.4 bits (125), Expect = 9e-06 Identities = 32/124 (25%), Positives = 56/124 (45%), Gaps = 7/124 (5%) Query: 22 IEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMF 81 IE +R + ++ F N+W FP+ GG AFLIP+ + + + G + Sbjct: 4 IESKRDQFNSKWGFILACIGSAVGMGNIWLFPFRVGQFGGAAFLIPYIIFVAVIGYTGVV 63 Query: 82 MELSFGQYAALGPVAVYNKFCPLFRG------LGYGMVIVSSIVMLYYNLIIAWTIFYMT 135 E+ FG+ GP + K RG +G+ VI S + + Y +++ W I + Sbjct: 64 EEMCFGRAMKTGPHGAFLK-ATRMRGSEAGNYIGWIPVIGSLGIAIGYTVVVGWIIRFAV 122 Query: 136 VSFS 139 +F+ Sbjct: 123 GAFT 126 >UniRef50_UPI00015B5071 Cluster: PREDICTED: similar to sodium/chloride dependent transporter; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to sodium/chloride dependent transporter - Nasonia vitripennis Length = 1583 Score = 84.2 bits (199), Expect = 9e-15 Identities = 81/358 (22%), Positives = 146/358 (40%), Gaps = 26/358 (7%) Query: 10 DEEKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFT 69 D+E+ + +E P G W N+ RF L G F++ F Sbjct: 669 DDERGEDEDEDENNP-LGRWPHALSPALACLGCTLGLFNISRFAILSIQFGAN-FIVQFL 726 Query: 70 VMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAW 129 ++ ++ G+PL+ +++ GQ A G V ++ K PLF+G+G ++ + + +Y + ++W Sbjct: 727 ILSLVIGIPLLTLQVCLGQRLAAGAVDMW-KISPLFQGVGIALLAAQAFIGIYSIVGVSW 785 Query: 130 TIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSH 189 Y SF + + W A + + NG N SY +S Sbjct: 786 MFVYFRDSFITKQDRYRWAEPFALYREDIRPTNSPGAAGSGPNGP----GNNNSSYKLSE 841 Query: 190 NITALAKTALRRPPAEEYFTNQVL---GLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCK 246 + +YF VL L+ ++ +A L W+IVF+ L K Sbjct: 842 TV-------------PDYFNGAVLQRHHLNEPDPGVVTLKFQVAFNLAVVWMIVFVSLSK 888 Query: 247 GVQSSGKVVYFTALFPYVVLVILFFR--GVTLPGAITGILFYLTPDFSQLANAQVWGDAA 304 G++S GKVVY L P ++L + G+T PG++ LF T N + W A+ Sbjct: 889 GLRSYGKVVYVFTLVPIFGTLVLCTKLLGLTPPGSLHQ-LFPGTVWAEFFINGRSWVAAS 947 Query: 305 VQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAH 362 ++F + ++++NK + D+ +V V A + + + L + Sbjct: 948 SEVFLTWGLLGAAAMQIAAHNKHKHLLQRDTSLVVVLTFVVLLLAAFLANTCVQILKY 1005 Score = 53.2 bits (122), Expect = 2e-05 Identities = 51/222 (22%), Positives = 93/222 (41%), Gaps = 23/222 (10%) Query: 392 ISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGW---VVFIVAVFGYLG 448 +SP W++LF+ +L+ G+ Q A+ V T I+ N + K W + F Y+ Sbjct: 1089 VSPFWAVLFYFILILFGIAQQLAIWHCVITGIM--AINTKMMKLWETTITFFSCACAYIL 1146 Query: 449 GLIFTTNSGMYWLQLMD-KYAANWSVLIIAIGECILIAWIYG----AEKFCGDIQRMIGR 503 GL T G+Y + +D W +L++ + + + + G + ++ GR Sbjct: 1147 GLPMATEFGIYVVYYLDYTVGGAWWILVLYLVQVAAVFAVRGRPHTGDAVVAELFPPTGR 1206 Query: 504 QSKLWV-YLWSAMWRIITPAALVF--ILVFNWIEYKPA-SYGHY---VYPMWADAVGWTX 556 + W L S W ++ P L+ I +F Y+ +Y + +WA +G + Sbjct: 1207 CLRYWAGPLLSFTWNVVLPITLMVLSITIFKSTGYRELYTYRRMNKDYWSIWARQLGASI 1266 Query: 557 XXXXXXXXXXXXXDQIC----SGPDDLTIMEKARVLARPTEE 594 Q C +GP D I ++ ++L RP+ E Sbjct: 1267 QLIPILMIPVVAVIQTCRYLNNGPPD--IFDRIQLLYRPSLE 1306 >UniRef50_A4A5L0 Cluster: Sodium-and chloride-dependent transporter; n=2; unclassified Gammaproteobacteria|Rep: Sodium-and chloride-dependent transporter - Congregibacter litoralis KT71 Length = 451 Score = 84.2 bits (199), Expect = 9e-15 Identities = 85/311 (27%), Positives = 138/311 (44%), Gaps = 24/311 (7%) Query: 228 GMAMCLLAAWVIVFLCLCKGVQSS-GKVVYFTALFPYVVLVILFFRGVTLPGAITGILFY 286 GM LA I L + GV++ + V + +LV L V G + + Sbjct: 151 GMLFWTLAGLAITGLIIFAGVKNGIERAVTIMMPLMFALLVALAGFNVFAGGFGEAVAWL 210 Query: 287 LTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATS 346 TPDFS+++ A V A Q FF++ GG++T SY S + LI+ +++ + Sbjct: 211 FTPDFSKVSFATVLA-AIGQAFFSIGVGMGGMMTYGSYLPRSISISQSVLIIVIADTGVA 269 Query: 347 FFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLT 406 AGLVIF + N +D GAGL F P ++P ++++LFF+ML T Sbjct: 270 LLAGLVIFPAV------FNYGLDPAA--GAGLIFQTLPVAFAQMPGGYIFAVLFFLMLAT 321 Query: 407 LGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDK 466 G+ S L+E+V I + + R K +V V L L + + M L+L D+ Sbjct: 322 AGITSMVGLVESVNAWIEEHYGVSRHKSAMIV--VGSIAVLSILSILSYNVMDELRLGDR 379 Query: 467 Y---AANW--SVLIIAIGE---CILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRI 518 AA++ + +++ +G I W E F + +G +W + R Sbjct: 380 NFNDAADYFSNQILLPLGGLFIAIFAGWFMRRE-FSREEFTTLGETG---YAIWYFLIRY 435 Query: 519 ITPAALVFILV 529 + P AL+ I V Sbjct: 436 VVPPALLVIFV 446 Score = 65.7 bits (153), Expect = 4e-09 Identities = 33/134 (24%), Positives = 68/134 (50%), Gaps = 6/134 (4%) Query: 28 NWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFG 87 +WT RF F N+WRFPY+ NGG AF++ + + G+P++ EL G Sbjct: 10 HWTSRFAFLMASVGFAVGLGNIWRFPYVTGENGGAAFVLIYLGCAFLIGVPILMAELMIG 69 Query: 88 QYA-ALGPVAVYNKF-----CPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSI 141 + A P+A+ N +R +G ++ + + + Y++++ W ++Y+ + ++ Sbjct: 70 RRGDAAPPIAMDNVARESGRSSQWRWVGGMGLLAAFTIEIVYSVVVGWVLWYLYKAITTG 129 Query: 142 FYQLPWQNCKAEWS 155 F + N +A+++ Sbjct: 130 FADVDALNAEAQFT 143 >UniRef50_A7HET8 Cluster: Sodium:neurotransmitter symporter precursor; n=1; Anaeromyxobacter sp. Fw109-5|Rep: Sodium:neurotransmitter symporter precursor - Anaeromyxobacter sp. Fw109-5 Length = 442 Score = 83.8 bits (198), Expect = 1e-14 Identities = 89/341 (26%), Positives = 154/341 (45%), Gaps = 29/341 (8%) Query: 191 ITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQS 250 + A+A+ A+ R A ++ S G T + +AM L A IV + G++ Sbjct: 114 LVAVARGAVERDTAAQF----AAAASGGAAVTWHL---VAMALTVA--IVAGGVRGGIER 164 Query: 251 SGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFA 310 + +V ALF V+L+ L TLP G FYL PD +++ + A Q FF+ Sbjct: 165 AS-LVLMPALF--VLLIALAAWAATLPDGGAGYAFYLRPDPARIWRLDTFTSAVGQAFFS 221 Query: 311 LSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDR 370 LS G ++T +SY + + + ++A+++ + +F GLV F ++ ++ + + Sbjct: 222 LSLGMGAMLTYASYLQKGGSLVREGFVIALADGSVAFAGGLVTFPIV----YQFGLQ-GQ 276 Query: 371 VVDQGAGLAFIVYPEVVTRL-PISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPN 429 V + G FI P L + FF+ LL L S +L+E + A++ R Sbjct: 277 VGESTVGALFIALPHAFATLGATGRIVGTAFFLALLIAALTSAISLLEVLVDAVVARTGW 336 Query: 430 FRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIY- 488 R++ V + L G+ + + WL D+ A N +++ + IL WI+ Sbjct: 337 SRRR---AVVLAGGATALAGVPAALD--LRWLGAADRIAGNLLLVVGGLIIAILTGWIWT 391 Query: 489 GAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILV 529 GA+ D R + W++L R+ PAAL +LV Sbjct: 392 GADAELAD-GFPHPRVRRAWIWL----LRVAIPAALALVLV 427 Score = 63.7 bits (148), Expect = 1e-08 Identities = 33/113 (29%), Positives = 53/113 (46%), Gaps = 2/113 (1%) Query: 23 EPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFM 82 EP R +W F N+WRF YL +GG AF++ + V++V+ G PL+ Sbjct: 3 EP-RPSWHSNVGFLLAAVGSAVGLGNLWRFAYLASESGGAAFVLVYLVVIVLVGAPLLVA 61 Query: 83 ELSFGQYAALGPVAVYNKFC-PLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYM 134 EL+ G+ A G + +G V+ ++ YY++I WT Y+ Sbjct: 62 ELAMGRSAREGAFRAPGRLVGRRLEWVGALFVLTGFAILSYYSVITGWTARYL 114 >UniRef50_A6PLC6 Cluster: Sodium:neurotransmitter symporter precursor; n=1; Victivallis vadensis ATCC BAA-548|Rep: Sodium:neurotransmitter symporter precursor - Victivallis vadensis ATCC BAA-548 Length = 531 Score = 83.8 bits (198), Expect = 1e-14 Identities = 73/277 (26%), Positives = 116/277 (41%), Gaps = 32/277 (11%) Query: 236 AWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLA 295 A ++++ + G++ K++ T F +LV L RGVTL GA G+ F+LTPDFS+L Sbjct: 197 AALMIWCGIRNGIERWSKILMPTLFF---LLVALLLRGVTLSGASKGVAFFLTPDFSKLT 253 Query: 296 NAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFS 355 A +A F+ LS IT SY N + +L V + + + AGL IF Sbjct: 254 AAGAL-EALGHAFYTLSLGMAITITYGSYLGRDKNIFTSALWVVLLDTGAALLAGLAIFP 312 Query: 356 VIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLP--ISPLWSILFFVMLLTLGLDSQF 413 + + + G L F V P P LW+ LFF+ML L S Sbjct: 313 AVFAMGFD--------PSDGPSLIFKVLPATFYNFPGGFGWLWAGLFFLMLTIAALTSAA 364 Query: 414 ALMETVTTAILDRFPNFRQKKGWVVFI-VAVFGYLGGL-----------------IFTTN 455 +L E T ++D+ R + ++ + FG L + +F Sbjct: 365 SLFECGVTFLIDQLGLKRSVAVILCYVGIGGFGVLTSVSCATWEHLPGVHGVLEYVFGEV 424 Query: 456 SGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEK 492 W L+D +NW + + + I + W++ K Sbjct: 425 KSKNWFVLLDYVTSNWMLPLSGLFTAIFVGWVWTTRK 461 Score = 57.6 bits (133), Expect = 9e-07 Identities = 22/74 (29%), Positives = 36/74 (48%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 +R NW F NVW+FPY+ NGGGAF++ + + + G+P+M E+ Sbjct: 5 KRENWGSTLGFVLAIAGSAIGLGNVWKFPYITGQNGGGAFVLVYLFCIFLLGMPIMLCEM 64 Query: 85 SFGQYAALGPVAVY 98 + G+ P + Sbjct: 65 AIGRKTRQNPYGAF 78 >UniRef50_Q5QY70 Cluster: Na+-dependent transporter of the SNF family; n=11; Proteobacteria|Rep: Na+-dependent transporter of the SNF family - Idiomarina loihiensis Length = 472 Score = 83.4 bits (197), Expect = 2e-14 Identities = 62/223 (27%), Positives = 110/223 (49%), Gaps = 11/223 (4%) Query: 228 GMAMCLLAAWVIVFLCLCKGV-QSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFY 286 G L+A +IV + L GV Q K F +++L++L ++L A+ G+ FY Sbjct: 141 GFVGFLIAVTIIVNVILLGGVRQGIEKAAKFLMPALFIMLILLVIFVLSLDNAVLGLEFY 200 Query: 287 LTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATS 346 L PDFS++ + + G A Q FF+LS G LIT SY ++ +VA+++ A + Sbjct: 201 LVPDFSKIDGSVING-ALSQAFFSLSLGMGILITYGSYFSRRDDIVTSGKLVALTDTAVA 259 Query: 347 FFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLP------ISPLWSILF 400 F AGL+ I A N + D + D + F +P++ L + + + +F Sbjct: 260 FTAGLMTLPAI--FAINPNTNPDSLSDSSVSMIFSFFPQIFIALEGVVGYVGASIAATIF 317 Query: 401 FVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAV 443 F++ + S +++E T A++++ +KK +V +AV Sbjct: 318 FLLTFIAAITSLVSILEVPTAAVIEQ-AKISRKKALLVMGIAV 359 Score = 54.8 bits (126), Expect = 7e-06 Identities = 29/113 (25%), Positives = 49/113 (43%), Gaps = 3/113 (2%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 +R ++ + F N+ FP NGGGAFLI + + + +P+M E+ Sbjct: 4 QRDQFSSKIGFILAAAGSAVGIGNLVGFPVAATKNGGGAFLIIYALFVAFICVPVMLAEM 63 Query: 85 SFGQYAALGPVAVYNKFCPLFRG---LGYGMVIVSSIVMLYYNLIIAWTIFYM 134 G+ A P+ Y P +G G VI ++ ++Y +I W Y+ Sbjct: 64 GLGRRAQKSPLGSYKALSPNNKGWHLAGLLAVITPFMIAVFYMVITVWIFGYL 116 >UniRef50_Q3A7I2 Cluster: Na+-dependent transporters of the SNF family; n=6; Desulfuromonadales|Rep: Na+-dependent transporters of the SNF family - Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1) Length = 468 Score = 83.0 bits (196), Expect = 2e-14 Identities = 78/314 (24%), Positives = 141/314 (44%), Gaps = 32/314 (10%) Query: 237 WVIVFLCLCKGVQSSG--KVV--YFTALFPYVV--LVILFFRGVTLPGAITGILFYLTPD 290 W +F+ LC G+ G K + + L P ++ LV+LF G+ GA + F PD Sbjct: 159 WHFIFISLCLGIVIGGVQKGIERWSKILMPILLGLLVLLFVNGMLSDGARQALNFMFRPD 218 Query: 291 FSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAG 350 F +L V +A FF LS +IT SY ++ + L +A+ + + AG Sbjct: 219 FQKLNPGAVL-EALGHAFFTLSLGMAAMITYGSYLSRQDSLFGSGLRIALLDTGIALMAG 277 Query: 351 LVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLD 410 L IF ++ S G GL F P V + LP + ++LFF++L L Sbjct: 278 LAIFPIV--------FSAGMQPGAGPGLVFQTIPVVFSNLPGGNILALLFFLLLAFAALT 329 Query: 411 SQFALMETVTTAILD-RFPNFRQKKGWVVFIVAVFG--------YLGGLIFTTNSGMYWL 461 S +L+E+ ++D R +Q ++ + V G LG L + G++ Sbjct: 330 SAISLLESQVAYLIDERGWGRKQATAFLAILAFVVGIPSALSSNLLGHLTPIADLGVF-- 387 Query: 462 QLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVY-LWSAMWRIIT 520 +D A+N+ + + + + + W + ++ + + ++ S W+Y W + R + Sbjct: 388 DSIDLIASNYLLPVSGLLTALYVGWFWSGQE---EKEELLAGGSG-WIYPTWHFLIRFVA 443 Query: 521 PAALVFILVFNWIE 534 P A V +++++ IE Sbjct: 444 PVA-VGVILYSKIE 456 Score = 75.8 bits (178), Expect = 3e-12 Identities = 33/121 (27%), Positives = 65/121 (53%), Gaps = 5/121 (4%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 R W R F N+W+FPY+ NNGGGAF++ + V + + GLP+M EL Sbjct: 8 RAQWGSRIGFILAAAGSAVGLGNIWKFPYITGNNGGGAFVLVYLVCIALVGLPIMIAELM 67 Query: 86 FGQYA---ALGP-VAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSI 141 G++ A+G +++ + P ++ G+ ++ + +++ YY+++ WT+ ++ + Sbjct: 68 IGRHTRRDAVGAFISLEGRRSP-WQIAGWVSILAAFVILSYYSVVAGWTLDFILRALQGA 126 Query: 142 F 142 F Sbjct: 127 F 127 >UniRef50_A6GC50 Cluster: Probable sodium-dependent transporter; n=1; Plesiocystis pacifica SIR-1|Rep: Probable sodium-dependent transporter - Plesiocystis pacifica SIR-1 Length = 456 Score = 83.0 bits (196), Expect = 2e-14 Identities = 34/118 (28%), Positives = 62/118 (52%), Gaps = 3/118 (2%) Query: 23 EPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFM 82 + RG W + F NVW+FPY+ NGGG F+I + + +V+ GLP+M Sbjct: 3 QERRGEWGSKIGFILAAAGSAVGLGNVWKFPYITGENGGGLFVIIYLICIVLVGLPIMIG 62 Query: 83 ELSFGQYAALGPVAVYNKF---CPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVS 137 E+ G+ PV + K L++G+G+ V+ +++ YY+++ W + Y+ ++ Sbjct: 63 EVMLGRMTQRSPVGAFRKLDGEKSLWQGVGWLGVLSGFVILSYYSVVAGWALEYVVIA 120 Score = 79.8 bits (188), Expect = 2e-13 Identities = 71/296 (23%), Positives = 128/296 (43%), Gaps = 25/296 (8%) Query: 246 KGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAV 305 KGV+ + +V+ L ++ L++ TL G G F +L + +A Sbjct: 168 KGVEIAARVLMPLLLLMFLALLVY---ATTLEGFGEGFNFVFGFHTDKLGAGSIL-EALG 223 Query: 306 QIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELN 365 FF LS G ++T SY + ++ S+ + + + + A LV+F + E Sbjct: 224 HSFFTLSVGMGAMLTYGSYLRKDDDIIGASVAITIIDTLVAIMACLVLFPITFTYGME-- 281 Query: 366 VSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILD 425 + G L F P ++P S +W+++FF++L+ L S +L+E + +D Sbjct: 282 ------PEAGPSLVFTNIPMAFAQIPGSTIWALIFFLLLVFAALTSAISLLEVCSAYFVD 335 Query: 426 RFPNFRQKKGWVV-FIVAVFGYLGGLIFTT---NSGM------YWLQLMDKYAANWSVLI 475 R V + + G L F+T SGM W L D ++NW + + Sbjct: 336 ELGWSRTLAVPVCGLTITLLGVPSALTFSTATFGSGMEAAIGKSWFDLFDYVSSNWMLPL 395 Query: 476 IAIGECILIAWIYG--AEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILV 529 +G + AW G A + + +G+ L+V LW + R + PAA+V +++ Sbjct: 396 CGLGISVFAAWKLGDEARRVQFEAGSTLGKLQGLYV-LWLQVLRYVVPAAIVVVML 450 >UniRef50_UPI00015563FA Cluster: PREDICTED: hypothetical protein, partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: hypothetical protein, partial - Ornithorhynchus anatinus Length = 392 Score = 82.6 bits (195), Expect = 3e-14 Identities = 42/102 (41%), Positives = 59/102 (57%) Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322 Y+VL+ L RG+ L GA G+ L S L + VW A Q+FFAL +G ++ + Sbjct: 1 YLVLLCLLIRGLLLDGANAGLKHMLQTQPSALLSIPVWRRAGTQVFFALGLGFGSVVAFA 60 Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHEL 364 SY NNC D+ +VA N+ATS A LV+++V+GF A L Sbjct: 61 SYTPRENNCARDAWVVAYINLATSLLATLVVYTVLGFRATTL 102 Score = 59.3 bits (137), Expect = 3e-07 Identities = 29/75 (38%), Positives = 44/75 (58%), Gaps = 5/75 (6%) Query: 360 LAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETV 419 L ELN V+ G GLAF+V+ E +T P +P W++LFF+MLL LGL + ++ + Sbjct: 166 LEEELNKGVE-----GPGLAFVVFTEALTLFPGAPFWAVLFFLMLLNLGLSTMLGTLQGI 220 Query: 420 TTAILDRFPNFRQKK 434 T + D F R+ + Sbjct: 221 LTPLQDAFHLLRRHR 235 >UniRef50_Q1N557 Cluster: Sodium-dependent transporter, NSS family protein; n=2; Proteobacteria|Rep: Sodium-dependent transporter, NSS family protein - Oceanobacter sp. RED65 Length = 442 Score = 82.2 bits (194), Expect = 4e-14 Identities = 36/117 (30%), Positives = 62/117 (52%) Query: 22 IEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMF 81 I+ +R W+ F N+WRFPY+ NGGGAFL+ + + L++ LP+M Sbjct: 8 IKQDRQQWSSEPAFIASMAGAAVGLGNLWRFPYMMGENGGGAFLVAYLIALIVVVLPIMM 67 Query: 82 MELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSF 138 +E++ G+ + G V + K R G+ +V+++ + YY +I WT+ Y +F Sbjct: 68 LEVAAGRLSKGGAVHTFGKINRFGRYYGWFVVLITVAITSYYLVITGWTLGYTVDAF 124 Score = 80.2 bits (189), Expect = 2e-13 Identities = 79/314 (25%), Positives = 138/314 (43%), Gaps = 36/314 (11%) Query: 229 MAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILF--FRGVTLPGAITGILFY 286 +A+ LLA +++ K ++++ K+ L P ++LVI++ F G F+ Sbjct: 145 IAVTLLAGAILIKGV--KAIETASKI-----LMPVLLLVIIYLVFEASQTSGWSQAKDFF 197 Query: 287 LTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATS 346 D+S+L N ++W A Q F+ L+ G LIT S+ N LIVA + + + Sbjct: 198 FVVDWSRLLNVELWAFAFGQAFYTLAIGQGYLITYGSFIPRDTNVPRACLIVAGTETSIA 257 Query: 347 FFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLT 406 AG +IF + S D G+ LAF+ P+V + ++LFF + Sbjct: 258 LLAGWMIFPFL--------FSFGMQPDAGSQLAFVTLPQVFASIDGGAYLAMLFFSLFFA 309 Query: 407 LGLDSQFALMETVTTAILDRFPNFR-QKKGWVVFIVAVFGYLGGLIFT-TNSGMYWLQLM 464 S A ++ + A+ + F Q WV ++ + G L FT N + ++ Sbjct: 310 AAFSSCLAGLKVLIAAVAEEFKQTNTQAVVWVCLLMLILGLFSALSFTPLNLNINGEPVL 369 Query: 465 DKYAANWSVLIIAIGECILIAWIYGAEKFC-----GDIQRMIGRQSKLWVYLWSAMWRII 519 D + IA G+ I+++ I GA FC I+ ++G +++ W WRI Sbjct: 370 D------VIDRIAGGDVIIVSGIMGAALFCWFIPPQTIRSVLGTENRWW------EWRIY 417 Query: 520 TPAALVFILVFNWI 533 + +LV W+ Sbjct: 418 LIGRFLPVLVVAWL 431 >UniRef50_A3VN81 Cluster: Sodium-dependent transporter family protein; n=1; Parvularcula bermudensis HTCC2503|Rep: Sodium-dependent transporter family protein - Parvularcula bermudensis HTCC2503 Length = 502 Score = 82.2 bits (194), Expect = 4e-14 Identities = 80/288 (27%), Positives = 130/288 (45%), Gaps = 12/288 (4%) Query: 187 VSHNITALAKTALRRPPAEEYFTNQVLG-LSSGIEETGEIRLGMAMCLLAAWVIVFLCLC 245 + A AL P E ++ G L + + G + + A+ + A I+ + Sbjct: 131 IGGRFVAEGPVALTAPAFEGQSDEEIGGILPKLLSQPGRMIVLHALFMAATVFILSRGVK 190 Query: 246 KGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAV 305 G++++ V+ +F ++L + F VT A+ + F TPDFSQL + + A Sbjct: 191 SGIEAAANVMM--PIFFVLLLGLTTFSLVT-GEAMQALTFLFTPDFSQLTGSTLLR-AVG 246 Query: 306 QIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELN 365 Q FF+LS ++T +Y + S IVA ++ A + AGL +F ++ F + L+ Sbjct: 247 QAFFSLSLGAAMMLTYGTYLSRETDIKSSSQIVATADTAVALIAGLALFPIV-FASPVLS 305 Query: 366 VSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMET-VTTAIL 424 V D G GL F+ P +P L+ + FFVM L L S AL+ET V+ A Sbjct: 306 ADVMGDNDPGLGLLFVTVPRAFHLMPFGSLFGLAFFVMALFAALTSAIALLETSVSWADG 365 Query: 425 D-RFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANW 471 D P ++ + V+ + LGGL F G Q+ AA + Sbjct: 366 DYDVPPAQKARRRVIGAIC----LGGLAFLIGIGHALSQVPQTVAATF 409 Score = 54.8 bits (126), Expect = 7e-06 Identities = 28/118 (23%), Positives = 56/118 (47%), Gaps = 12/118 (10%) Query: 28 NWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFG 87 NW+GR F N+ RFPY+ ++GGGAF+ + ++ G+P++ E G Sbjct: 12 NWSGRAAFILAAVGSAVGLGNLVRFPYVAGDSGGGAFIFVYLATILFIGVPVLIAEFMIG 71 Query: 88 QYAALGPVAVYNKFC---------PLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTV 136 + +A ++ +F LG ++ S +++ YY+++ W + ++ V Sbjct: 72 RRGGGSAIAAVSRLARTEGRTRAWVIFPILG---ILASFLIVSYYSVLAGWILHFIQV 126 >UniRef50_Q8MSR0 Cluster: Transporter; n=3; Sophophora|Rep: Transporter - Drosophila melanogaster (Fruit fly) Length = 1331 Score = 81.8 bits (193), Expect = 5e-14 Identities = 79/287 (27%), Positives = 124/287 (43%), Gaps = 36/287 (12%) Query: 48 NVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRG 107 N+ RF L N GG FL+ F ++ VI G+PL+++++ G GPV+++ K P+ G Sbjct: 516 NMCRFAVLTINFGGN-FLLQFLLLSVIFGIPLLWLQMCLGAKIRAGPVSMW-KISPICAG 573 Query: 108 LGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ-LPWQNCKAEWSTKHCYSYEEAD 166 +G +V+ + LY + +AW + Y+ F + WQ E + + Y Sbjct: 574 VGIALVMQQCFLALYSTVSLAWILVYLRDVFPTAARSGYRWQ----EMAFPYRY------ 623 Query: 167 ECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIR 226 +A N T L Q + + N+ L + L P +SGI R Sbjct: 624 --DASNATGNLTQTVAEYF----NVVVLQRLHLANHPD-----------ASGIRFHVNDR 666 Query: 227 LGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILF--FRGVTLPGAITGIL 284 +A L W VFL LCKG++S GK+ Y P V L ++ F V P I I Sbjct: 667 -QLAFYLALIWAAVFLILCKGLKSLGKLAYIIYTLPLVALAVVTAKFVYVVDPSRIQNI- 724 Query: 285 FYLTPDFSQ-LANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNN 330 + DF L N+ W A + F +I ++S + + N Sbjct: 725 -FAASDFDDFLVNSNSWTAATQETFLTWGLLGASVIAITSRSHTNAN 770 >UniRef50_Q8RHM5 Cluster: Sodium-dependent tyrosine transporter; n=7; Bacteria|Rep: Sodium-dependent tyrosine transporter - Fusobacterium nucleatum subsp. nucleatum Length = 438 Score = 81.4 bits (192), Expect = 7e-14 Identities = 65/245 (26%), Positives = 104/245 (42%), Gaps = 10/245 (4%) Query: 234 LAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQ 293 +A V+ L L G +S K +V+ IL R LPGAI G + PD+S Sbjct: 151 IAVIVLTLLTLFAGAKSIEKTNKIMMPAFFVLFFILAVRVAFLPGAIEGYKYLFVPDWSY 210 Query: 294 LANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVI 353 L+N + W +A Q FF+LS G+I +Y + +L V + + A V+ Sbjct: 211 LSNVETWINAMGQAFFSLSITGSGMIVCGAYLDKKEDIINGALQTGVFDTIAAMIAAFVV 270 Query: 354 FSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQF 413 + + G L F+ PEV ++P L +ILFFV ++ + S Sbjct: 271 IPA--------SFAFGYPASAGPSLMFMTIPEVFKQMPFGQLLAILFFVSVVFAAISSLQ 322 Query: 414 ALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSV 473 + E V +I RF R K +V + + +G I N W+ ++ Y + Sbjct: 323 NMFEVVGESIQTRFKMTR--KSVIVLLGIIALVIGIFIEPENKVGPWMDVVTIYIIPFGA 380 Query: 474 LIIAI 478 ++ AI Sbjct: 381 VLGAI 385 Score = 38.7 bits (86), Expect = 0.47 Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 6/90 (6%) Query: 48 NVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYN-KFCPLFR 106 N+W FPY GG FL+ + + + + + E G+ A G + Y + + + Sbjct: 27 NIWAFPYRVGKYGGAVFLLIYFMFIALFSYVGLSAEYLIGRRAETGTLGSYEYAWKDVGK 86 Query: 107 G-LGYGMVIV----SSIVMLYYNLIIAWTI 131 G LGYG+ + S + + Y +I AW + Sbjct: 87 GKLGYGLAYIPLLGSMSIAIGYAVIAAWVL 116 >UniRef50_A6PRZ0 Cluster: Transporter; n=2; Bacteria|Rep: Transporter - Victivallis vadensis ATCC BAA-548 Length = 497 Score = 81.4 bits (192), Expect = 7e-14 Identities = 64/227 (28%), Positives = 104/227 (45%), Gaps = 15/227 (6%) Query: 211 QVLGLSSGIEETGEIRLG-MAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVIL 269 +++G +G + +G M + +L V +L L KGV+ K++ LF ++L+ L Sbjct: 172 EIIGYFNGFLASPGRNVGYMLLTVLIGSVTCYLGLQKGVERITKLM-MAGLF--LLLLGL 228 Query: 270 FFRGVTLPGAITGILFYLTPDFSQLANAQVWG---DAAVQIFFALSPAWGGLITLSSYNK 326 R TLPGA G+ FYL P L ++ A Q FF LS G + SY Sbjct: 229 CIRSCTLPGASAGLSFYLKPSLEPLETVGLFNIIVAALGQAFFTLSLGVGSIAIFGSYID 288 Query: 327 FSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEV 386 ++ +SL++ + + AG++IF + VD G GL FI P V Sbjct: 289 RDHSLAKESLVIIALDTIVAILAGVIIFPAC------FSYGVD--AGSGPGLVFISLPNV 340 Query: 387 VTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK 433 +P W +LFF+ L + L + A+ E + ++D + R+K Sbjct: 341 FNHMPGGRWWGVLFFLFLSSAALTTVIAVFENLIAFMIDEWRLSRRK 387 Score = 56.0 bits (129), Expect = 3e-06 Identities = 31/91 (34%), Positives = 47/91 (51%), Gaps = 6/91 (6%) Query: 48 NVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCP---L 104 N+WRFP++ NGG F++ + V L + G P+M MELS G+ + Y K P Sbjct: 66 NIWRFPFVTGQNGGALFVLIYLVFLFMLGFPVMVMELSLGRASRRNLYGAY-KTLPKGSS 124 Query: 105 FRGLGYGMVIV--SSIVMLYYNLIIAWTIFY 133 F+ G V S+ +M++Y + W I Y Sbjct: 125 FKWHWPGAVFFTGSAFLMIFYTTVTGWMIAY 155 >UniRef50_A0RQG4 Cluster: Sodium-and chloride-dependent transporter; n=19; Campylobacter|Rep: Sodium-and chloride-dependent transporter - Campylobacter fetus subsp. fetus (strain 82-40) Length = 458 Score = 81.4 bits (192), Expect = 7e-14 Identities = 78/327 (23%), Positives = 145/327 (44%), Gaps = 31/327 (9%) Query: 227 LGMAMCLLAAWVIVFLCLCKGVQSSGK---VVYFTALFPYVVLVILFFRGVTLPGAITGI 283 + + +C +++VF + KG++S + + +LF +VL++L+ + G ++ + Sbjct: 139 ISVFICFTLVFLLVFYVVSKGIKSGIERLNIWMMPSLFGLLVLLLLYSIFQS-GGFVSAV 197 Query: 284 LFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNI 343 F PDFS+L N + A FF++S G + T ++ N + + NI Sbjct: 198 QFLFIPDFSKLLNPSIILQALGLAFFSMSMGVGTVATYAASLPDGTNLIKSTFSIVSINI 257 Query: 344 ATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRL-PISPLWSILFFV 402 GLV+FS I + + +GAGL F+ + ++ + + +I FF+ Sbjct: 258 LIGIMMGLVVFSFI-------PIQDGQPASEGAGLIFVSLTSLFAQMGVVGNVLAIAFFI 310 Query: 403 MLLTLGLDSQFALMETVTTAILDRFPNFRQKK----GWVVFIV---AVFGYLGGL----- 450 LL G+ S +++E T ++++F R+ G +V+I+ + Y G Sbjct: 311 SLLFAGVTSAVSMIEPFTLYLINKFNISRKMSITFIGVLVYILGICCILSYYGDTSASFS 370 Query: 451 ----IFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSK 506 IF T + + ++D +N + I A+ I + WI K G G SK Sbjct: 371 LPKEIFATQKPVPFFDMLDFMTSNVLMPIGALTFSIFVGWIL---KRDGLYILFSGFISK 427 Query: 507 LWVYLWSAMWRIITPAALVFILVFNWI 533 W +W R + P A++ I V+ I Sbjct: 428 TWFEIWYFALRYVAPIAIIAIGVYQLI 454 Score = 53.2 bits (122), Expect = 2e-05 Identities = 25/97 (25%), Positives = 50/97 (51%), Gaps = 3/97 (3%) Query: 48 NVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFR- 106 N W+FP + NNGG AF++ + ++ + + + EL+ G+ V K P + Sbjct: 23 NAWKFPTMVGNNGGSAFILLYVLLTLGIAVVVFLAELAIGKLGETDIVGSLYKLAPKHKK 82 Query: 107 --GLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSI 141 L +I + ++ +Y ++I W + Y+ +SFS++ Sbjct: 83 QWSLAGFFMITAVLIASFYMIVIGWILKYIFMSFSTL 119 >UniRef50_Q9HPQ2 Cluster: Daunorubicin resistance ABC transporter ATP-binding protein; n=2; Halobacteriaceae|Rep: Daunorubicin resistance ABC transporter ATP-binding protein - Halobacterium salinarium (Halobacterium halobium) Length = 447 Score = 81.4 bits (192), Expect = 7e-14 Identities = 67/246 (27%), Positives = 110/246 (44%), Gaps = 14/246 (5%) Query: 247 GVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLAN--AQVWGDAA 304 G++ + K++ + L V+LV L TL G FYL+PDF +A+ + A Sbjct: 160 GIEKATKLMVPSIL---VMLVGLAVYASTLNGVGAAYEFYLSPDFGFIADNIGSIVPYAV 216 Query: 305 VQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHEL 364 Q FF+LS G +IT +SY ++ + D ++ V N + AGLV VI L + Sbjct: 217 SQAFFSLSLGMGAMITYASYLGDDDSLFADGGLIVVLNTSVGLLAGLV---VIPLLFVQF 273 Query: 365 NVSVDRVVDQGAGLAFIVYPEVVTRLPIS-PLWSILFFVMLLTLGLDSQFALMETVTTAI 423 D GAG FI + L ++ + +LFF ++L L S +L+E VT + Sbjct: 274 GTVPDAAAGGGAGALFISVAQAFATLGVAGRVLGVLFFGVVLVAALSSAISLLEVVTAYV 333 Query: 424 LDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECIL 483 +D N+ + F + G + N+ WL D A + + + + Sbjct: 334 VD---NYGYSRPATAFSFGGVLFALGTLSAWNTA--WLDWFDSLAYGVLLPLSVLLGVVF 388 Query: 484 IAWIYG 489 + W+YG Sbjct: 389 VGWVYG 394 Score = 63.3 bits (147), Expect = 2e-08 Identities = 30/123 (24%), Positives = 56/123 (45%), Gaps = 1/123 (0%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 ER W R F N+W+FP+ GG AF++ + V ++ GLP + E Sbjct: 3 ERETWASRLGFILAAVGSAVGLGNIWQFPFKTATEGGAAFVVVYLVAALLLGLPAILGEF 62 Query: 85 SFGQYAALGPVAVYNKF-CPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFY 143 G+ A L V +++ P + +G ++ ++ YY+++ W Y+ S + ++ Sbjct: 63 VIGRRANLNAVEAFDRLDHPAWTIVGAMGLLTGLWILSYYSVVGGWVTRYLLGSATGAYF 122 Query: 144 QLP 146 P Sbjct: 123 AAP 125 >UniRef50_Q5QUN5 Cluster: Na+-dependent transporter of the SNF family; n=7; Alteromonadales|Rep: Na+-dependent transporter of the SNF family - Idiomarina loihiensis Length = 439 Score = 80.2 bits (189), Expect = 2e-13 Identities = 73/228 (32%), Positives = 111/228 (48%), Gaps = 10/228 (4%) Query: 230 AMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTP 289 A+ LLA +VF + KG++ K + T + V+LV L +TLPGA G+ YL P Sbjct: 145 AVFLLATAYVVFQGVEKGIERWSKRLMPTLV---VLLVALIAYMLTLPGADEGLKKYLVP 201 Query: 290 DFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFA 349 DFS + + + A Q FF+LS GG++ SY K N SL VA + +F A Sbjct: 202 DFSLMTDTSILVAAMGQAFFSLSIGLGGMMIYGSYLKPGANLGRLSLSVAALDTFIAFLA 261 Query: 350 GLVIFSVIGFLAHELNVSV---DRVVDQGAGLAFIVYPEVVTRLPIS-PLWSILFFVMLL 405 GL+I + + L V+V +++ +G L F V PE+ + I+ P + FF++L Sbjct: 262 GLLIIPAL-YAGIHLGVNVGEGSKLIGEGQ-LIFAVLPELFNSMGIAGPFVAFAFFMLLS 319 Query: 406 TLGLDSQFALMET-VTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIF 452 L S A E V+ I +R + ++A+F L L F Sbjct: 320 IAALTSTIAQAEVPVSYCIEERKLKRPVATALSLSVIAMFSLLLILFF 367 Score = 60.1 bits (139), Expect = 2e-07 Identities = 29/113 (25%), Positives = 54/113 (47%), Gaps = 5/113 (4%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 R ++ R F N+W FP N+GGGAFL+ + ++ I +P ++ E+ Sbjct: 2 RDSFHSRIGFILAAAGSAVGLGNIWGFPTQVANHGGGAFLLVYLCVIFILAIPALYSEML 61 Query: 86 FGQYAALGPVAVYNKFC-----PLFRGLGYGMVIVSSIVMLYYNLIIAWTIFY 133 G A PV + P+ R +GY V+ S +++ +Y+++ W + + Sbjct: 62 IGHSAQANPVRSLTQLSEGRARPIGRLMGYLNVLGSCLMLSFYHVVAGWMLVH 114 >UniRef50_Q7NPX3 Cluster: Transporter; n=5; Proteobacteria|Rep: Transporter - Chromobacterium violaceum Length = 437 Score = 79.4 bits (187), Expect = 3e-13 Identities = 77/250 (30%), Positives = 113/250 (45%), Gaps = 21/250 (8%) Query: 246 KGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAV 305 KG++ +GK++ LF ++++ L R VTLPGA+ G+ PDFS+L + +A Sbjct: 163 KGIERAGKLL-MPLLF--LLMLALIVRAVTLPGAMAGVAALFRPDFSRLTPGMLV-EALG 218 Query: 306 QIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELN 365 F+LS G ++ SY +L V TS AGL+IF I A LN Sbjct: 219 LACFSLSVGAGCMLAYGSYLGPGTRLGNSALWVTGLTALTSVLAGLMIFPAI--YAFGLN 276 Query: 366 VSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILD 425 G GL ++V P V LP L++ FF +LL L S +L+E V +D Sbjct: 277 PQA------GPGLTYMVMPVVFNHLPYGQLFATAFFALLLMAALTSAVSLLEVVAILPID 330 Query: 426 RFPNFRQKKGWVV----FIVAVFGYL--GGLIFTTNSGMYWLQLMDKYAANWSVLIIAIG 479 F R++ V F+ V L G L G +LMD A+N + + IG Sbjct: 331 EFGVGRRQATLAVTALAFLAGVPAALSFGPLADCKLFGRTAFELMDYAASNVLLPLGCIG 390 Query: 480 ECIL---IAW 486 + +AW Sbjct: 391 TALFAGRVAW 400 Score = 76.6 bits (180), Expect = 2e-12 Identities = 34/110 (30%), Positives = 57/110 (51%), Gaps = 1/110 (0%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 R W R F ++W+FPY+ NGGGAFL+ + GL L+ EL+ Sbjct: 3 RTQWGSRLGFILASAGATVGLGSIWKFPYVTAMNGGGAFLLVYLAFTFTLGLALLQAELA 62 Query: 86 FGQYAALGPVAVYNKF-CPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYM 134 G+ A G V +++ P ++ LGYG V+ ++ +Y+++ WT+ Y+ Sbjct: 63 LGRAAGCGAVGAFSRLGSPRWKLLGYGGVLCCFLIFSFYSVVGGWTLGYL 112 >UniRef50_Q4LEH9 Cluster: Sodium-dependent transporter; n=1; uncultured crenarchaeote 45-H-12|Rep: Sodium-dependent transporter - uncultured crenarchaeote 45-H-12 Length = 438 Score = 79.4 bits (187), Expect = 3e-13 Identities = 59/274 (21%), Positives = 133/274 (48%), Gaps = 19/274 (6%) Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322 + +L+ L G+++ G+ +Y PD ++L + VW A Q FF+LS G L+T + Sbjct: 171 FAMLIPLALIGLSMDRDGLGLRYYTQPDSNRLLDPHVWSSAIGQAFFSLSIGLGVLVTYA 230 Query: 323 SY-NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFI 381 SY + + + SLI+ S + +F +GL++F+++ A+ L G L FI Sbjct: 231 SYVREQKQSVVVTSLIIVGSVLVVAFLSGLMVFTMV--FANGLGDV------HGTALVFI 282 Query: 382 VYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIV 441 P+++ + L I FF++L G+ S ++++ +A+ D F + + V+ ++ Sbjct: 283 AMPKIIAGMEYGYLLGITFFLLLFIAGITSSISMLQIPVSALEDTFKFSKARATMVITML 342 Query: 442 AV-FGYLGGLIFT-TNSGMYWLQLMDKYAANWSVLIIAIGECIL---IAWIYGAEKFCGD 496 ++ G L ++ + + + ++D + + + +A+ ++ +AW + + Sbjct: 343 SLALGIPSALSYSPVHLSISSMPVLDAFDWIFGTIALAVSATLMAVAVAWFMSRD----E 398 Query: 497 IQRMIGRQSKLWV-YLWSAMWRIITPAALVFILV 529 + + S++ + + RI+ PA ++ L+ Sbjct: 399 MMEQVNMNSRIRIPSRMLDLVRILLPAMIIATLM 432 Score = 70.9 bits (166), Expect = 9e-11 Identities = 32/118 (27%), Positives = 56/118 (47%) Query: 20 EEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPL 79 E + ER W F ++WRFPY+ NGG +FL+ + ++L GL Sbjct: 2 ERVGRERETWGSYTGFILTTIGSAVGIGSIWRFPYMVSTNGGASFLLVYIIVLFTFGLAF 61 Query: 80 MFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVS 137 M +E + G V+ + FR +G M+ V+ ++ YY +++ W + Y+ +S Sbjct: 62 MVLEFALGMRYRTSIVSALSMIRHRFRFIGLFMIGVTVAILSYYMVVLGWILAYLVMS 119 >UniRef50_Q6MBR5 Cluster: Transporter; n=1; Candidatus Protochlamydia amoebophila UWE25|Rep: Transporter - Protochlamydia amoebophila (strain UWE25) Length = 466 Score = 78.6 bits (185), Expect = 5e-13 Identities = 83/308 (26%), Positives = 126/308 (40%), Gaps = 26/308 (8%) Query: 237 WVIVFLCLCKGVQSSG---KVVYFTALFPYVVLVILFFR---GVTLPGAITGILFYLTPD 290 W +F L V G + Y++ +L+IL TLPG G+ F PD Sbjct: 149 WHFLFTALTAAVVYRGIRQGIEYWSRFMTIGLLIILLSMCAYAFTLPGFREGVNFIFYPD 208 Query: 291 FSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAG 350 S+ + DA FF LS G ++T SY + +N ++I+ V + S AG Sbjct: 209 LSRFKPSAAI-DALGLSFFTLSLGQGIMLTYGSYMRRGDNIPKTAVIIGVMIVLISLLAG 267 Query: 351 LVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLD 410 L+IF +I S + G GL F P + +LP + S FFV+ + L Sbjct: 268 LMIFPII--------FSFGFAPEAGPGLVFKTLPVLFAQLPGALFISTAFFVLFVFTALT 319 Query: 411 SQFALMETVTTAILDRFPNFRQKKGWVVFIVA-VFGYLGGL-----IFTTNSGMY---WL 461 S AL+E VT D RQK +V I +FG L +F +Y + Sbjct: 320 SAVALIEVVTANFTDLLGWSRQKAVLIVSISCFIFGIPSALSNTNTLFANWPAIYGKTFF 379 Query: 462 QLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITP 521 Q +D W + I + I W+ +K + G + + W R + P Sbjct: 380 QTIDDLVTLWFLPIGGLLVSIFTGWV--LDKELAKEEFSSGTTMRWLWHPWIFFIRWVAP 437 Query: 522 AALVFILV 529 A+VFI++ Sbjct: 438 IAIVFIIL 445 Score = 65.3 bits (152), Expect = 5e-09 Identities = 29/124 (23%), Positives = 59/124 (47%), Gaps = 3/124 (2%) Query: 22 IEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMF 81 ++ +R +W+ F +W+FPY+ NGGG F+ + + G+P+ Sbjct: 1 MQKQREHWSSHLGFILAAAGSAIGLGTLWKFPYVTGENGGGLFVFIYILCTFFIGVPVFI 60 Query: 82 MELSFGQYAALGPVAVYNKFC---PLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSF 138 EL G+ A G V ++ ++ +G+ V S ++M +Y+++ W + Y+ +S Sbjct: 61 AELILGRKAQRGAVGIFASLANNSAAWKTVGWLGVASSFLIMSFYSILAGWGLNYIFMSL 120 Query: 139 SSIF 142 S + Sbjct: 121 SQFY 124 >UniRef50_Q3INN0 Cluster: Transporter 55; n=1; Natronomonas pharaonis DSM 2160|Rep: Transporter 55 - Natronomonas pharaonis (strain DSM 2160 / ATCC 35678) Length = 442 Score = 77.8 bits (183), Expect = 8e-13 Identities = 72/298 (24%), Positives = 135/298 (45%), Gaps = 30/298 (10%) Query: 239 IVFLCLCKGVQSSGKVVYFTALFPYVVLVI--LFFRGVTLPGAITGILFYLTPDFSQLAN 296 IV L + +G++ + K A+ P + L++ L +TL G + G +YL+PDF+ LA Sbjct: 151 IVMLGIKRGIELAVK-----AMVPAIALLLAGLAVYALTLDGVVDGYRYYLSPDFATLAA 205 Query: 297 --AQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIF 354 + A Q F LS G +IT +SY + +DS +A+ + +F +GL++F Sbjct: 206 EWTTILPAAVGQALFTLSLGMGVMITYASYVGEDQSLLVDSGSIALLDTVIAFLSGLILF 265 Query: 355 SVIGFLAHELNVSVDRVV-DQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQF 413 ++ ++D D GAG FI +P+ + ++FFV L L S Sbjct: 266 PIL--------FTIDATPGDGGAGEFFIGVGGAFADIPLGTIVGVVFFVTLAVAALSSAI 317 Query: 414 ALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSV 473 +++E + + +D F R+ F V V ++ G+ + G + ++ D+ Sbjct: 318 SILEVIVSYFIDEFGFDRRV---ATFGVGVIVFVAGIPAALDMGTF--EVYDQVTGE--- 369 Query: 474 LIIAIGECIL---IAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFIL 528 L++ +G +L +AW+ E ++ G ++ +LW + L +L Sbjct: 370 LLLPLGMFLLVLFVAWVVPEESLDELLKGRSGSNLDVF-WLWWVRTVVTVAVGLTLVL 426 Score = 73.3 bits (172), Expect = 2e-11 Identities = 31/120 (25%), Positives = 57/120 (47%), Gaps = 1/120 (0%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 ER W R F N+WRFP+ NGG AFLI + +++ G+P + +E Sbjct: 2 ERETWATRIGFILAAVGSAVGLGNIWRFPFQVGQNGGSAFLIMYLACVLLIGIPAILVEF 61 Query: 85 SFGQYAALGPVAVYNKF-CPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFY 143 G+ + P+ ++ FR +G V+ +++ YY ++ W + Y+ S + ++ Sbjct: 62 VIGRRSQRNPIGAFHALGKSRFRAIGAVCVVTGFVILSYYTVVAGWVLRYIGGSATGAYF 121 >UniRef50_A4BUI1 Cluster: Probable sodium-dependent transporter; n=1; Nitrococcus mobilis Nb-231|Rep: Probable sodium-dependent transporter - Nitrococcus mobilis Nb-231 Length = 433 Score = 77.4 bits (182), Expect = 1e-12 Identities = 37/123 (30%), Positives = 62/123 (50%), Gaps = 2/123 (1%) Query: 22 IEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMF 81 +E RG+W+ R F N+W+FPY+ NGG AF+ + V + LP++ Sbjct: 3 VESVRGSWSNRLGFVLAAAGSAVGLGNIWKFPYMAGKNGGAAFIFVYIVSVFAICLPIVV 62 Query: 82 MELSFGQYAALGPVAVYNKFCP-LFRGLGYGMVIVSSIVML-YYNLIIAWTIFYMTVSFS 139 EL G+ + PV + P F LG + ++S ++L +Y ++ WT+ +M +S S Sbjct: 63 AELMLGRTSRRNPVGAFQSLRPRSFWVLGGWLGVLSGFLILSFYGVVAGWTLDFMLLSAS 122 Query: 140 SIF 142 F Sbjct: 123 GSF 125 Score = 77.4 bits (182), Expect = 1e-12 Identities = 78/302 (25%), Positives = 135/302 (44%), Gaps = 27/302 (8%) Query: 230 AMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRG--VTLPGAITGILFYL 287 A+ ++A +IV + G++ ++ L P ++L+++ G +TL GA F L Sbjct: 152 ALFMVATIIIVAGGIASGIERGSRI-----LLPALLLMLIGLVGFSLTLSGAGDAAAFLL 206 Query: 288 TPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSF 347 TP + + + + A Q FF+LS G +IT SY + + VA+++ A + Sbjct: 207 TPRWEEFSGESLLA-ALGQAFFSLSLGMGVMITYGSYLGSGESLSRSAFYVALTDTAVAL 265 Query: 348 FAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTL 407 AG IF ++ E G GL F P +LP + L + FF++L Sbjct: 266 LAGAAIFPIVFTFGFEPAA--------GPGLTFQTLPVAFAQLPWAGLLAFTFFLLLSLA 317 Query: 408 GLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKY 467 L S +L+E V +D + R W F V +L G+ +S W++ +D Sbjct: 318 ALTSSISLLEVVVAYFIDEWRWRRVTAAW--FCGGV-TFLAGVPCAVDSA--WIERLDAL 372 Query: 468 AANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFI 527 +N+ + IG +LIA G + + +G + + W M R ++PAA+V I Sbjct: 373 TSNY---FLPIGG-LLIAAFAGWVLVPAEQESELG--TNVLTRTWRFMIRWVSPAAVVAI 426 Query: 528 LV 529 + Sbjct: 427 FL 428 >UniRef50_Q1N1Z9 Cluster: Na+-dependent transporter of the SNF family protein; n=1; Oceanobacter sp. RED65|Rep: Na+-dependent transporter of the SNF family protein - Oceanobacter sp. RED65 Length = 355 Score = 76.6 bits (180), Expect = 2e-12 Identities = 63/197 (31%), Positives = 100/197 (50%), Gaps = 10/197 (5%) Query: 234 LAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQ 293 L A VIV L + G++ K++ T L ++L+I+ +TL GA GI +Y T DFSQ Sbjct: 144 LTACVIV-LGVKNGIERLSKILMPTLL---LLLIIMIIWVLTLDGASKGISWYFTSDFSQ 199 Query: 294 LANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVI 353 L + ++ G A Q FF+LS G++T +Y K S V + + + +F AGL+I Sbjct: 200 L-SPELLGRALGQAFFSLSIGVTGMMTYGAYLKRSRGLPKTVASVTLLDTSVAFLAGLLI 258 Query: 354 FSVIGFLAHELNVSVDRVVDQGAG---LAFIVYPEVVTRLPISPLW-SILFFVMLLTLGL 409 + A ++V Q G L F + P + L ++ L SILFFV+LL + Sbjct: 259 LPALS-AAQAQGITVFNGAGQLIGSDKLVFDILPALFANLGVTGLLISILFFVLLLIAAI 317 Query: 410 DSQFALMETVTTAILDR 426 S ++ME + ++ Sbjct: 318 TSSISMMEPPVNTLQEK 334 Score = 61.3 bits (142), Expect = 8e-08 Identities = 26/108 (24%), Positives = 52/108 (48%), Gaps = 6/108 (5%) Query: 28 NWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFG 87 ++T + F N+W FP NNGGG FL+ + M+V+ G P++ E++ G Sbjct: 5 HFTSKLGFIAAAAGSAVGLGNIWGFPTEAANNGGGTFLLIYFAMVVLVGYPMLLAEVTIG 64 Query: 88 QYAALGPVAVYNKFCP------LFRGLGYGMVIVSSIVMLYYNLIIAW 129 A P+ ++ + G+G+ + +++ +Y+++ AW Sbjct: 65 NLAQANPIDALSRLTQKAKSRIVLAGIGWAGTLTILLILSFYSVVGAW 112 >UniRef50_Q6MLR2 Cluster: Sodium-dependent serine transporter; n=1; Bdellovibrio bacteriovorus|Rep: Sodium-dependent serine transporter - Bdellovibrio bacteriovorus Length = 455 Score = 76.2 bits (179), Expect = 3e-12 Identities = 37/122 (30%), Positives = 62/122 (50%), Gaps = 4/122 (3%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 +RG+W R+ F N+WRFPY+ NGGGAF++ + ++ + G PL+ EL Sbjct: 4 KRGSWKTRYGFYLLAIGSACGLGNLWRFPYVVGENGGGAFILLYGLLALAIGAPLLIAEL 63 Query: 85 SFGQYAALGPVAVYNKFCPL----FRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSS 140 G+ + + FR +G V+VS +V+ YY++I W + ++T S Sbjct: 64 MLGKGTRRSVIVATQQMSAKTGVNFRWVGRLAVMVSIVVLSYYSVISGWVLHFLTQFLVS 123 Query: 141 IF 142 +F Sbjct: 124 LF 125 Score = 67.3 bits (157), Expect = 1e-09 Identities = 67/261 (25%), Positives = 116/261 (44%), Gaps = 21/261 (8%) Query: 238 VIVFLCLCKGVQSSGK--VVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLA 295 +I + + KGVQ + + Y LF V+++IL R +LP + F PDFS+L+ Sbjct: 156 LITVVVVVKGVQQGLERWIGYTMPLFA-VLVIILVMRSFSLPSTPEVLRFLFYPDFSKLS 214 Query: 296 NAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFS 355 + A +FF LS +G ++T SY + ++ V + + S A ++IF Sbjct: 215 WDSI-NHALGHVFFTLSVGFGTMVTFGSYMREEDHVPTAGFRVTIVDTVISLVAVVMIFP 273 Query: 356 VIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFAL 415 V F A + ++ L F V P+ + + L+ + FF L L++ L Sbjct: 274 V-AFQASNVPLT-------DPALMFEVLPKYLLGIRGGTLFGLAFFACLYMAALNASIGL 325 Query: 416 METVTTAILDRFPNFRQKK-----GWVVFIVAVFGYLGGLIF--TTNSGMYWLQLMDKYA 468 +E V + +D + K G + ++ V L IF G ++ +D Sbjct: 326 LEVVVSNWVDAKKEMERGKATWYSGAIALMLTVLPALSSSIFKDIRVGGRSLIENLDSLL 385 Query: 469 ANWSVLIIAIGECILIAWIYG 489 NW + ++A+G ILIA+ G Sbjct: 386 INWLLPLVALG--ILIAFNRG 404 >UniRef50_O25240 Cluster: Sodium-and chloride-dependent transporter; n=4; Helicobacter|Rep: Sodium-and chloride-dependent transporter - Helicobacter pylori (Campylobacter pylori) Length = 442 Score = 75.8 bits (178), Expect = 3e-12 Identities = 66/224 (29%), Positives = 109/224 (48%), Gaps = 16/224 (7%) Query: 227 LGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFY 286 +G + CLL V + +G++ VV LF V+ + L +TL + F Sbjct: 142 IGFSACLLPTIWFVSRGIEEGIEKLN-VVLMPLLF--VIFIGLLIYAMTLESMPKALHFL 198 Query: 287 LTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATS 346 + ++ + +V DA Q+FF+LS G +IT S++ N + SL + + I S Sbjct: 199 FNFEIQKI-DFKVVMDALGQMFFSLSLGVGTIITYSAFTPKKENLFKSSLFIVLPGILIS 257 Query: 347 FFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPIS-PLWSILFFVMLL 405 AG++IF+ + F H D V QG GL FI P ++ +S + S+ FF+ L+ Sbjct: 258 LIAGVMIFTFV-FEYH-----AD--VSQGPGLVFISLPLTFAKMGMSGQIVSLFFFMALV 309 Query: 406 TLGLDSQFALMETVTTAILDRFPNFR--QKKGWVVFIVAVFGYL 447 G+ S +L+E + +++RF NF Q W+ +V V G L Sbjct: 310 FAGITSTVSLIEPLALYLINRF-NFSRLQASLWIGVVVYVLGVL 352 Score = 52.4 bits (120), Expect = 4e-05 Identities = 21/92 (22%), Positives = 49/92 (53%), Gaps = 3/92 (3%) Query: 48 NVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCP---L 104 ++WRFPY+ +NGG AF++ + V+ + G+ ++ +E+ G V+ Y P Sbjct: 22 HIWRFPYMVGHNGGSAFVLLYLVLTLSLGIAMLLVEMLIGNLGKKDVVSNYQILDPKRKK 81 Query: 105 FRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTV 136 + ++ +++ +Y +++ W ++Y+ V Sbjct: 82 YYPFTSFFILGGPLILSFYAVVLGWVLYYLFV 113 >UniRef50_A6VX44 Cluster: Transporter; n=12; Gammaproteobacteria|Rep: Transporter - Marinomonas sp. MWYL1 Length = 466 Score = 75.8 bits (178), Expect = 3e-12 Identities = 72/309 (23%), Positives = 129/309 (41%), Gaps = 27/309 (8%) Query: 234 LAAWVIVFLCLCKGVQ----SSGKVVYFTALFPYVVLVILFFRGVTLPGA--ITGILFYL 287 L W+ V L L G+ G L P +++++L G + + G+ F Sbjct: 164 LTIWMTVVLGLTMGIVLRGLHGGLEKAINLLMPGLLILLLILVGYAMTSGHFMEGVSFLF 223 Query: 288 TPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSF 347 DFS++ A FF LS A G ++T SY + + ++I+A+ + + Sbjct: 224 KADFSKMTGTGFLV-ALGHAFFTLSLASGAIMTYGSYLPENVSIGKTTMIIAIMDTVVAL 282 Query: 348 FAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTL 407 AGL IF ++ A+ L G GL F+ P ++P + LFF++L Sbjct: 283 AAGLAIFPLV--FANGLEPGA------GPGLIFVTLPIAFGQMPFGSTFGTLFFLLLAVA 334 Query: 408 GLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYW------- 460 L S +++E + + ++F R K + + G L G++ + N G W Sbjct: 335 ALTSAISMLEPTISWLTEKFKMTRFKACMLAGSLLWLGGL-GVVASLNIGSEWTLFGKTF 393 Query: 461 LQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIIT 520 ++D ++W + + + I WI +Q +G S + LW R IT Sbjct: 394 FDMLDYLTSSWLMPLGGLLMAIFSGWILKKTV----MQDELGLSSTIMHKLWLFTMRYIT 449 Query: 521 PAALVFILV 529 P A++ + + Sbjct: 450 PLAIIIVFL 458 Score = 62.9 bits (146), Expect = 3e-08 Identities = 29/123 (23%), Positives = 60/123 (48%), Gaps = 6/123 (4%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 R W+ R F N+W+FPY+ +GGGAF++ + ++I G+P+M E++ Sbjct: 20 RVQWSTRMAFILAAVGSAVGLGNIWKFPYITGEHGGGAFVLVYLGCILIIGIPVMMAEIA 79 Query: 86 FGQYAALGP---VAVYNKFC---PLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFS 139 G+ P +A + P ++ +G ++ +++++Y ++ W Y+ + S Sbjct: 80 LGRRGRHNPAQGIATLVREAGAHPFWKIIGVMALLCGFMILMFYTVVAGWAFAYVPKAAS 139 Query: 140 SIF 142 F Sbjct: 140 GSF 142 >UniRef50_Q6I1C4 Cluster: Sodium-dependent transporter, putative; n=30; Bacilli|Rep: Sodium-dependent transporter, putative - Bacillus anthracis Length = 452 Score = 75.4 bits (177), Expect = 4e-12 Identities = 52/178 (29%), Positives = 85/178 (47%), Gaps = 12/178 (6%) Query: 246 KGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAV 305 KG++ + K Y L +++ + + R +TL GA G+ F+L PDFS+L V A Sbjct: 166 KGIEKASK--YMMPLL-FILFIAIIVRALTLDGAFAGVEFFLKPDFSKLTADTVLY-AMG 221 Query: 306 QIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELN 365 Q FF+L+ ++T SSY K + + + + + AGL IF I L + Sbjct: 222 QSFFSLTVGASVMVTYSSYLKKEEHLAKSATSIVSLTVFITVLAGLAIFPAIFALGVKPT 281 Query: 366 VSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAI 423 +G GL FIV P V ++P + I+F V+ L S +++E V ++ Sbjct: 282 --------EGPGLLFIVLPAVFAKIPFGQFFFIMFLVLFFFATLTSAISMLEIVVASV 331 Score = 69.3 bits (162), Expect = 3e-10 Identities = 32/122 (26%), Positives = 55/122 (45%), Gaps = 3/122 (2%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 E WT + F +W+FPY+ N GGGAF + F ++ + G+PL+ E Sbjct: 4 ETQQWTSKIGFVLAAAGAAVGLGAIWKFPYVAGNGGGGAFFLVFLLLTLFIGMPLLLAEF 63 Query: 85 SFGQYAALGPVAVYNKFCP---LFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSI 141 G+ V Y P L+ +G V+ V+ +Y+++ W + Y+ S + Sbjct: 64 VIGRSTQKEAVTAYKVLVPNSKLYPWIGRMGVVTCFSVLSFYSVVGGWILLYLYYSITGS 123 Query: 142 FY 143 F+ Sbjct: 124 FW 125 >UniRef50_Q0A4P9 Cluster: Transporter; n=1; Alkalilimnicola ehrlichei MLHE-1|Rep: Transporter - Alkalilimnicola ehrlichei (strain MLHE-1) Length = 461 Score = 74.9 bits (176), Expect = 6e-12 Identities = 69/259 (26%), Positives = 109/259 (42%), Gaps = 24/259 (9%) Query: 215 LSSGIEETGEIRLGMA--MCLLAAWVIVFLCLCKGVQSSG------KVVYFTALFPYVVL 266 L +G + GE+ G+ L W VF+ LC V S G K V F +++L Sbjct: 133 LDAGADRVGELFAGLLDRPLELVLWHSVFMALCFAVVSRGVRSGLEKAVRFLMPALFLLL 192 Query: 267 VILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGD-------AAVQIFFALSPAWGGLI 319 ++L G+ + + PD +L G A Q FF LS G ++ Sbjct: 193 ILLVGYGMGAGAFAEAMRYLFLPDLGELLAGGEAGSLGALMLGAVGQAFFTLSLGMGAIM 252 Query: 320 TLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLA 379 SY ++ +S+I+A ++ A + AGL +F ++ +V D GAGL Sbjct: 253 VYGSYLSSRSSIPQNSVIIAGADTAIALIAGLAVFPIV--------FAVGLEPDSGAGLV 304 Query: 380 FIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVF 439 FI ++P L+ LFFV+L S ++ME T +++ R++ VV Sbjct: 305 FITLSAGFGQMPAGALFGTLFFVLLSFAAWTSAISIMEPATAYLVENRGWSRRRAAAVVA 364 Query: 440 IVA-VFGYLGGLIFTTNSG 457 + A G L L SG Sbjct: 365 LAAWAMGILSALSLNVMSG 383 Score = 70.5 bits (165), Expect = 1e-10 Identities = 30/122 (24%), Positives = 61/122 (50%), Gaps = 6/122 (4%) Query: 27 GNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSF 86 G W R+ F N+WRFPY+ +GGGAF++ + + ++ G+P+M E+ Sbjct: 11 GQWGSRWAFILAATGSAVGLGNIWRFPYVVGESGGGAFVVVYLLFVLGVGIPVMMGEILL 70 Query: 87 GQYAALGPVAVYNKFCPLFRG------LGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSS 140 G++ P+ + C + LG+ V+ I++ +Y+++ W++ Y+ ++ Sbjct: 71 GRHGRQSPINTLSTLCREYGTQRAWVLLGWMGVLAGFIILSFYSVVAGWSLAYVPMTAGG 130 Query: 141 IF 142 F Sbjct: 131 AF 132 >UniRef50_Q8E9E5 Cluster: Sodium-dependent transporter, putative; n=16; Alteromonadales|Rep: Sodium-dependent transporter, putative - Shewanella oneidensis Length = 454 Score = 74.5 bits (175), Expect = 8e-12 Identities = 72/307 (23%), Positives = 142/307 (46%), Gaps = 22/307 (7%) Query: 239 IVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGV----TLPGAITGILFYLTPDFSQL 294 +VFL L +GVQ G + L P +L+I+ GV +L GA GI LTP+F++ Sbjct: 158 LVFLVLLQGVQE-GIEKWSKRLMP--LLLIMLIAGVAYIFSLNGASEGISALLTPNFAKA 214 Query: 295 ANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIF 354 +A Q FF+L+ G ++ SY N ++ VA ++ +F A +I Sbjct: 215 IAPDTLINALGQTFFSLTIGTGAMMVYGSYLSQKENIAKLTVWVAFTDSGIAFLAAFLII 274 Query: 355 SVIGFLAHELNVSV----DRVVDQGAGLAFIVYPEVVTRL--PISPLWSILFFVMLLTLG 408 + ++A V + +++D A L F V P + + L + + S++FF++L+ G Sbjct: 275 PAM-YVAQHNGVQIFSPEGKLIDSDA-LVFTVLPALFSTLGDTANLIISVVFFMLLIIAG 332 Query: 409 LDSQFALMETVTTAILDRFPNFRQKKGWVV-FIVAVFGYLGGLIFTTNSGMYWLQLMDKY 467 L S ++ E T+ ++ + RQ+ ++ ++ L + F T ++ +M Sbjct: 333 LTSAISIAEVPTSYVMQKCGFSRQRATLIIGLLLTALSLLLAVFFET---LFSFTIM--L 387 Query: 468 AANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSK-LWVYLWSAMWRIITPAALVF 526 + ++A+G I + WI+ + I + G + L+ +W + + P ++ Sbjct: 388 TTQMTQPLVALGIAIYLGWIWRQSQLLKAISKQEGVDATGLFWRIWPRYVKYVCPVLIIA 447 Query: 527 ILVFNWI 533 I + ++ Sbjct: 448 IAIRQFV 454 Score = 61.3 bits (142), Expect = 8e-08 Identities = 30/121 (24%), Positives = 58/121 (47%), Gaps = 6/121 (4%) Query: 28 NWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFG 87 +++ R F N+W FP +GGGAFL+ + V++ I G+P++ EL G Sbjct: 11 HFSSRLGFIMAAAGSAVGVGNIWGFPTQAATHGGGAFLLVYLVLIFILGIPMLMAELMIG 70 Query: 88 QYAALGPVAVYNKF-C-PLFRGLG--YGM--VIVSSIVMLYYNLIIAWTIFYMTVSFSSI 141 ++ P K C L R LG G+ ++ + ++ +Y+++ W + + ++ Sbjct: 71 RHGQTNPADAMGKLGCNSLTRSLGKTIGLISIVTAGLIYTFYSILSGWFVSFAIAPIATA 130 Query: 142 F 142 F Sbjct: 131 F 131 >UniRef50_Q83A23 Cluster: Transporter; n=4; Coxiella burnetii|Rep: Transporter - Coxiella burnetii Length = 450 Score = 74.1 bits (174), Expect = 1e-11 Identities = 36/126 (28%), Positives = 63/126 (50%), Gaps = 6/126 (4%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 R W+ + F N+WRFPY+ GG AFL+ + + ++I GLP+M E+ Sbjct: 12 RERWSSKLAFILAATGAAVGLGNIWRFPYMAGMYGGSAFLLIYLIFVLIIGLPIMIAEIL 71 Query: 86 FGQYAALGPV------AVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFS 139 G+ + PV A + + LG+ + +++ +Y+++ W + Y+ SFS Sbjct: 72 IGRRSRKNPVDALITLAQESNHSRKWGLLGWLGALALLLILSFYSVVAGWNVAYLIKSFS 131 Query: 140 SIFYQL 145 + FYQL Sbjct: 132 NEFYQL 137 Score = 42.3 bits (95), Expect = 0.038 Identities = 48/214 (22%), Positives = 85/214 (39%), Gaps = 10/214 (4%) Query: 239 IVFLCLCKGVQSS-GKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANA 297 + + + KGV+ K F YV+L IL + G F + S++ + Sbjct: 166 LTMVVVAKGVKGGLEKATKFMMPALYVILFILVIYAFSYGNFNKGFHFLFDFNHSKITTS 225 Query: 298 QVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVI 357 V A FF L+ G + +Y + N LIVA ++ + +GL IF ++ Sbjct: 226 VVIA-ALGHAFFTLALGAGAMAMYGAYVPRNVNLGKTVLIVASLDVLVAILSGLAIFPIV 284 Query: 358 GFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALME 417 A+ L + G GL ++ P ++ L L F++LL S L E Sbjct: 285 --FAYHL------PPNSGPGLMYVTLPIILAHLSSGWFIGGLCFLLLLFAAWTSSINLAE 336 Query: 418 TVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLI 451 + + +R R ++ + A F +G ++ Sbjct: 337 PLVVILTERLGLKRTYAAIIIGLTAWFIGIGSVL 370 >UniRef50_A1HTE8 Cluster: Transporter; n=1; Thermosinus carboxydivorans Nor1|Rep: Transporter - Thermosinus carboxydivorans Nor1 Length = 330 Score = 74.1 bits (174), Expect = 1e-11 Identities = 34/109 (31%), Positives = 58/109 (53%), Gaps = 2/109 (1%) Query: 48 NVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCP--LF 105 N+W+FPYL GGGAFL+ + V +++ GLP+M E G+ A V + K P + Sbjct: 34 NIWKFPYLTGQYGGGAFLMVYLVCILLVGLPVMLGEFYIGRKARRNAVGAFAKLAPRTAW 93 Query: 106 RGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEW 154 + G V+ ++M +Y+ + W FY+ + F Q+ + KA++ Sbjct: 94 KHTGTLAVLAVYLIMFFYSCVAGWVYFYLFKALRGEFAQVSLETAKAQF 142 Score = 45.6 bits (103), Expect = 0.004 Identities = 35/102 (34%), Positives = 49/102 (48%), Gaps = 5/102 (4%) Query: 238 VIVFLCLCKGVQSSGKVVYFTAL-FPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLAN 296 V+V L GVQ + + T + +++++I R +TLPGA G+ F DFS+L Sbjct: 161 VVVSAILMLGVQKGIEKITKTLMPLLFILILICDIRALTLPGAAEGLNFLFQVDFSKLTP 220 Query: 297 AQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNN---CYIDS 335 + A FF LS G +IT SSY N CY S Sbjct: 221 TVIL-TALGLAFFKLSLGMGVMITYSSYFTADTNFLHCYESS 261 >UniRef50_Q892Y6 Cluster: Sodium dependent amino acid transporter; n=4; Clostridia|Rep: Sodium dependent amino acid transporter - Clostridium tetani Length = 247 Score = 73.3 bits (172), Expect = 2e-11 Identities = 57/226 (25%), Positives = 98/226 (43%), Gaps = 17/226 (7%) Query: 276 LPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDS 335 +PGA+ G+ + + P + L W A Q FF +S G++ SY K + S Sbjct: 1 MPGAMEGVAYLVKPRWGYLLKPITWVMALGQAFFTVSLNGAGMVVYGSYLKEEEDIPKAS 60 Query: 336 LIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPL 395 + +A+ + ++ A VI + A LN S G L FI P V +P Sbjct: 61 MQIAIFDTLSALLAAFVIIPAV--FAFGLNPSA------GPSLLFITMPYVFKSMPFGYA 112 Query: 396 WSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGG--LIFT 453 + +LFF+ ++ + S +ME + A L +F R K V I+++ ++ G L + Sbjct: 113 FGVLFFISIIFAAVSSLINMMEATSEAFLSQFKIGRIKG---VAIISIIAFIIGMPLNLS 169 Query: 454 TNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQR 499 N+ W + Y A ++ A + WIYG + +I + Sbjct: 170 MNAFGKWADFVTIYLAPLGTMVSA----VTFFWIYGMDNALVEINK 211 >UniRef50_Q0IBN8 Cluster: Na+-dependent transporter of the SNF family protein; n=20; Cyanobacteria|Rep: Na+-dependent transporter of the SNF family protein - Synechococcus sp. (strain CC9311) Length = 461 Score = 73.3 bits (172), Expect = 2e-11 Identities = 68/281 (24%), Positives = 125/281 (44%), Gaps = 15/281 (5%) Query: 263 YVVLVILFFRGVTLPGAITGI-LFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITL 321 +V+LV L TL GA+ G F L D +QL N +A Q FF++ G ++ Sbjct: 192 FVLLVGLALWAATLSGAVGGYQTFLLRWDAAQLLNPTTIRNAFTQAFFSIGTGIGCILAY 251 Query: 322 SSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFI 381 S+Y S +++ V + A AGLV F V+ + VS V G F+ Sbjct: 252 SAYLNSSARLPREAIAVVGLDTAVGLLAGLVTFPVVISFGLQETVSESTV-----GALFL 306 Query: 382 VYPEVVTRL-PISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFI 440 P + L L ++LFF + + S +L+E +++DR R++ W + Sbjct: 307 AIPTGLASLGSAGRLVAVLFFSLAYLAAITSSVSLLEVPVASLMDRLGWSRRRSAW---L 363 Query: 441 VAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRM 500 +A+ ++ GL + + L++MD +++ + +L+ W+ ++F D+Q Sbjct: 364 MALLIFIAGLPAAMSIPV--LEVMDSIFGGVLLILGGLLIALLVGWVV-PKRFRNDLQGS 420 Query: 501 IGRQSKLWVYLWSAMW--RIITPAALVFILVFNWIEYKPAS 539 + + L+ W + A L+ +V W ++ PA+ Sbjct: 421 KTSAGLIGLMLFFLRWVSPAVITAGLLISVVDLWRQWFPAA 461 Score = 55.6 bits (128), Expect = 4e-06 Identities = 28/107 (26%), Positives = 52/107 (48%), Gaps = 7/107 (6%) Query: 28 NWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFG 87 +W F F N+W F Y GGGAFL+ + +++++ LP++ E+ G Sbjct: 22 HWRSGFGFVLAAAGSAVGLGNLWGFAYRASQGGGGAFLLLYVLIVLVVCLPVLVAEMVLG 81 Query: 88 QYAA----LGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWT 130 + A L P+A K + +G+ V+ S ++ +Y +++ WT Sbjct: 82 RSTAQSPLLAPIAAAGK---AWWPMGWLFVLASCGILAFYAVLMGWT 125 >UniRef50_A7HQJ6 Cluster: Sodium:neurotransmitter symporter precursor; n=1; Parvibaculum lavamentivorans DS-1|Rep: Sodium:neurotransmitter symporter precursor - Parvibaculum lavamentivorans DS-1 Length = 457 Score = 73.3 bits (172), Expect = 2e-11 Identities = 34/120 (28%), Positives = 58/120 (48%), Gaps = 6/120 (5%) Query: 29 WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQ 88 W+ RF F N+WRFPYL NGGGAF++ + + + LP++ E+ G+ Sbjct: 10 WSSRFAFLMAAIGSAVGLGNIWRFPYLAGENGGGAFIVIYAITTMGIALPILVSEIMLGR 69 Query: 89 YAALGPVAVYNKFCPLFRG------LGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIF 142 P+ K R +G+G + + IV+ YY++I W + Y+ ++ + F Sbjct: 70 MGRQSPINTMRKLIAENRAARFWTLIGWGGTVGAFIVLSYYSVIGGWALKYVELALTGAF 129 Score = 58.0 bits (134), Expect = 7e-07 Identities = 75/331 (22%), Positives = 137/331 (41%), Gaps = 33/331 (9%) Query: 216 SSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVT 275 S+ + + + L + L A IV + G++ + VV L + +LV + T Sbjct: 142 SAFVTDPYSVALWQTLFLAATIFIVAAGVTSGIERA--VVLLMPLL-FFLLVGMAIYATT 198 Query: 276 LPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDS 335 PG ++F +F ++ + A Q FF++S A G ++T +Y + + Sbjct: 199 TPGFGEAMIFMFAFEFHEVTPDTILA-AIGQGFFSVSVALGAMMTYGAYLDKDVSIGRSA 257 Query: 336 LIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPL 395 +++AV++ + AG+ IF ++ ++ L S G GL FI P + L Sbjct: 258 IVIAVADTLVALLAGIAIFPLV--FSYGLEPS------SGPGLTFITLPIAFGTIGGGVL 309 Query: 396 WSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTN 455 FF++L + S +L+E V + + + W+ IV ++ G I T Sbjct: 310 IGAAFFLLLSVAAITSAISLLEPVVAWVEE---GIHIPRKWLALIVGGAAWVAG-IGTVL 365 Query: 456 SGMYW--------LQLM-DKYA------ANWSVLIIAIGECILIAWIYGAEKFCGDIQRM 500 S W L LM DK ++++ +G +L++ G + Sbjct: 366 SFNLWADFHPLAGLGLMADKTVFDVLDFTTSNIVMPTVG--LLMSLFAGWVLSSSAAEEA 423 Query: 501 IGRQSKLWVYLWSAMWRIITPAALVFILVFN 531 +G + KLW LW R + P ++ I V N Sbjct: 424 LGARGKLWFRLWRFALRYVAPLGVMSIFVAN 454 >UniRef50_Q8DBI3 Cluster: Sodium-dependent transporter; n=50; Vibrionales|Rep: Sodium-dependent transporter - Vibrio vulnificus Length = 454 Score = 72.9 bits (171), Expect = 2e-11 Identities = 67/300 (22%), Positives = 137/300 (45%), Gaps = 15/300 (5%) Query: 237 WVIVFLCLCKGVQSSGKVVYFTALFP--YVVLVILFFRGVTLPGAITGILFYLTPDFSQL 294 +V+ L + GV+ G + T L P +V+ +LF +T GA+ G+ YL PDF ++ Sbjct: 157 YVLTILIVQGGVKQ-GIEKWSTRLMPALFVLFAVLFIYIMTQNGAMEGLKHYLVPDFDKV 215 Query: 295 ANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIF 354 + ++ A Q FF+L+ ++ SY N ++ V + + A +F AGLV+ Sbjct: 216 WDRKLILAAMGQGFFSLTIGGCSMLIYGSYLSKKENLPKMAMNVTLVDTAVAFIAGLVVL 275 Query: 355 SVIGFLAHELNVSV---DRVVDQGAGLAFIVYPEVVTRLP-ISPLWSILFFVMLLTLGLD 410 + F+A + V + D + L F V P + L + +++++FF++L L Sbjct: 276 PAM-FVAMQKGVQIYAEDGSLLSSDTLVFTVLPLMFDSLGLLGQIFAVVFFLLLTIAALT 334 Query: 411 SQFALMETVTTAILDRFPNFRQKKGWVV-FIVAVFGYLGGLIFTTNSGMYWLQLMDKYAA 469 S +++E + +RF R WV+ ++A+F ++ N G + L+ A Sbjct: 335 SSISMLECPVALVGERFNTKRSTTSWVLGGLIALF----SVVIVYNFGALF-GLVATIAT 389 Query: 470 NWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWV-YLWSAMWRIITPAALVFIL 528 + A+ C+ W++ ++++ + W +W + + + P + ++ Sbjct: 390 QYLQPTAALLFCLFGGWVWSRHSKIKELEQGNPEFTLGWFGKVWPSYVKFVCPVLVATVI 449 Score = 60.5 bits (140), Expect = 1e-07 Identities = 33/116 (28%), Positives = 58/116 (50%), Gaps = 8/116 (6%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 R ++ R F N+W FP +NGGGAFL+ + VM++I P++ +E++ Sbjct: 10 REHFGSRLGFILAAAGAAVGLGNIWGFPTQAASNGGGAFLLVYLVMILIVAFPMLVVEMA 69 Query: 86 FGQYAALGPVAVYNKFC--PLFRGLGYGMV-----IVSSIVMLYYNLIIAWTIFYM 134 G++ PV P+ + +G G+V V S V+ +Y+++ W I +M Sbjct: 70 IGRHGQANPVDSMRALTSHPVGKKVG-GLVGWIGLSVPSAVLAFYSIVGGWIICFM 124 >UniRef50_A7CWE7 Cluster: Sodium:neurotransmitter symporter; n=1; Opitutaceae bacterium TAV2|Rep: Sodium:neurotransmitter symporter - Opitutaceae bacterium TAV2 Length = 536 Score = 72.9 bits (171), Expect = 2e-11 Identities = 78/308 (25%), Positives = 144/308 (46%), Gaps = 20/308 (6%) Query: 205 EEYFTNQVLGLSSGIE-ETGEIRLGMAMCLLAAWVIVFLC--LCKGVQSSGK----VVYF 257 +E+F S+G+ + G +G+ + L+ + FL L KG++ + + V+ Sbjct: 136 KEFFATYTGAGSNGVALQFGLSDVGLFVVLVIVVNLFFLYRGLSKGIELACRWGMPVLIL 195 Query: 258 TALFPYVVLVILFFRGVTLP--GAITGILFYLTP-DFSQ-LANAQVWGDAAVQIFFALSP 313 A+ V ++ L T P ++ + F P D Q L + Q+W A QIFF+LS Sbjct: 196 IAIVIMVRVLTLGTPDATRPELNVLSALGFMWNPGDILQSLKSPQLWLAAGSQIFFSLSI 255 Query: 314 AWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVD 373 G +IT +SY + +++ + SL +N F +V+ + A + + V Sbjct: 256 GLGIIITYASYLRKTDDITLSSLTAVGANE----FCEVVLGGLTTVSAAFMFLGAAGVAG 311 Query: 374 QGA-GLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQ 432 QG L FIV PEV + + P+++ LFFV+L + S ++++ T A L+ FR Sbjct: 312 QGTFALGFIVLPEVFSHMTGGPVFAALFFVLLFLAAITSSLSILQP-TIAFLEE--AFRM 368 Query: 433 KKGWVVFIVAVFGYLG-GLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAE 491 ++ + +A +G G ++ + + L +D + V + + IL AW+ G + Sbjct: 369 RRAVSITWLATLLVIGTGFVWFFSKDLKALDTIDFWVGTVGVYLQGLLIVILFAWVIGID 428 Query: 492 KFCGDIQR 499 K ++ R Sbjct: 429 KSWREMHR 436 Score = 50.0 bits (114), Expect = 2e-04 Identities = 34/111 (30%), Positives = 50/111 (45%), Gaps = 6/111 (5%) Query: 29 WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQ 88 W+ RF N RFP L GGGAF+I + V L++ G+P+ + E + G+ Sbjct: 9 WSSRFGVILAVASSAVGLGNFLRFPGLAAQYGGGAFMIAYFVSLLVIGIPVSWAEWTVGR 68 Query: 89 YAA-LGPVAVYNKFCPLFRG-----LGYGMVIVSSIVMLYYNLIIAWTIFY 133 + G + F L R LG +V +V +YY I AW + Y Sbjct: 69 HGGHFGYHSSPGIFHALLRRPWAKYLGALGFMVPLMVCMYYVYIEAWCLGY 119 >UniRef50_Q7M9R0 Cluster: Transporter; n=1; Wolinella succinogenes|Rep: Transporter - Wolinella succinogenes Length = 443 Score = 72.1 bits (169), Expect = 4e-11 Identities = 37/115 (32%), Positives = 59/115 (51%), Gaps = 7/115 (6%) Query: 32 RFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAA 91 R F NVW+FPY+ NGGGAF+ F + +V GL + E+ G+ + Sbjct: 6 RIGFILAAAGSAIGLGNVWKFPYMTGQNGGGAFVAIFLLSVVFIGLTVFLAEMILGRTSE 65 Query: 92 LGPVAVYNKFCPLFRGLGY----GMVIVSSIVML-YYNLIIAWTIFYMTVSFSSI 141 PV+ Y P G Y G +I+S +++L +Y++++ W I Y+ VS S + Sbjct: 66 KNPVSTYESLAP--HGGRYWKYAGFMILSGVLILSFYSVVVGWLIHYIFVSLSGL 118 Score = 65.7 bits (153), Expect = 4e-09 Identities = 65/276 (23%), Positives = 116/276 (42%), Gaps = 21/276 (7%) Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322 +++ + L F +++ + F TP + ++ NA V + Q FF LS G ++T S Sbjct: 175 FLIFIALLFYALSMDSFGKSLAFMFTPHWEKI-NANVVLMSVGQAFFTLSLGVGTIMTYS 233 Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIV 382 + N +L VA + + AGLVIF+ + + + G GL FI Sbjct: 234 ASLPKKGNFVSSALYVAFLDTLLAVVAGLVIFTFLFEFGSDPS--------GGPGLVFIS 285 Query: 383 YPEVVTRLP-ISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVV--- 438 P + ++ + L S+LFF+ LL G+ S +L E + +++R R K W V Sbjct: 286 LPVIFAQMGLVGQLISLLFFIALLFAGITSAISLAEPLLGYLIERRSWKRSKAVWAVMGV 345 Query: 439 -FIVAVFGYLGGLIFTTNS----GMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKF 493 + + V LGG S G +D ++ + + + CI + ++ + Sbjct: 346 SYALGVLAILGGSKAYGESLKWGGKSIFDWLDFGSSALLMPLAGVALCIFVGFVLDKNRV 405 Query: 494 CGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILV 529 G G + +W R + P A+ IL+ Sbjct: 406 YG---MFGGYMPPFFFKIWLFCVRFVAPVAIFIILI 438 >UniRef50_Q9JRT7 Cluster: Sodium-dependent transporter, putative; n=9; Chlamydiaceae|Rep: Sodium-dependent transporter, putative - Chlamydia pneumoniae (Chlamydophila pneumoniae) Length = 494 Score = 71.7 bits (168), Expect = 5e-11 Identities = 49/186 (26%), Positives = 85/186 (45%), Gaps = 8/186 (4%) Query: 236 AWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLA 295 A++++ + G++ K++ A F + + L R VTLPGA+ GI + D S + Sbjct: 152 AYLVIRKGIVHGIEKCNKIL-IPAFF--LCTIALLLRAVTLPGAVQGIKQLFSCDKSCFS 208 Query: 296 NAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFS 355 N +VW +A Q + WG L+ + + + + A+ N S G++IFS Sbjct: 209 NYKVWIEALTQNAWDTGAGWGLLLVYAGFASKKTGVVSNGALTAICNNLVSLIMGIIIFS 268 Query: 356 VIGFLAHELNVSV-DRVVDQGAGLAFIVYPEVVTRLP----ISPLWSILFFVMLLTLGLD 410 L + D G+ FI PE+ TRLP ++ L+S +FF+ L Sbjct: 269 TCASLDILGTTQLQDGAGASSIGITFIYLPELFTRLPGGIYLTTLFSSIFFLAFSMAALS 328 Query: 411 SQFALM 416 S +++ Sbjct: 329 SMISML 334 Score = 68.1 bits (159), Expect = 7e-10 Identities = 35/116 (30%), Positives = 57/116 (49%), Gaps = 3/116 (2%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 + +++ R F N+WRFP + NGGGAFLI + L + +PL+ +EL Sbjct: 4 KHASFSSRLGFIFSMIGIAVGAGNIWRFPRVAAQNGGGAFLILWLCFLFLWSIPLIIIEL 63 Query: 85 SFGQYAALGPVAVYNKFC-PLFRGLGYGMVIVSSIVMLYYNLIIAW--TIFYMTVS 137 S G+ P+ K F G + +V++ ++ YY+ I+ W + FY VS Sbjct: 64 SIGKLTKKAPIGALIKTAGKKFAWAGGFITLVTTCILAYYSTIVGWGLSYFYYAVS 119 >UniRef50_UPI0000D56C34 Cluster: PREDICTED: similar to solute carrier family 6 (neurotransmitter transporter, dopamine), member 3; n=1; Tribolium castaneum|Rep: PREDICTED: similar to solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 - Tribolium castaneum Length = 533 Score = 71.3 bits (167), Expect = 7e-11 Identities = 61/329 (18%), Positives = 136/329 (41%), Gaps = 9/329 (2%) Query: 205 EEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264 E+++ N+VL G + + + L +++F G +++ K + A P V Sbjct: 123 EQFYFNRVLNTDETSGYVGAPQPELLVYGLVTIILIFFANYGGPKTTEKFLLVLATVPTV 182 Query: 265 VLVILFFRGVTLPGAITGILFYLTP-DFSQLANAQVWGDAAVQIFFALSPAWGGLITLSS 323 +V+LFF ++ + + T D L+N + W + +G I + Sbjct: 183 QMVVLFFAPLSDQNGFVTLNYLFTQLDVKNLSNFKTWTRIINLSLSSPGLGFGAFIAFGT 242 Query: 324 YNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVY 383 + F + ++I++V+++ + +++ + + L + + D L Sbjct: 243 QSTFRTPLHFKAIIISVTSVLFTVLYSIIVQNFLISLCIQSQMLFDDFFKLEQELEM--- 299 Query: 384 PEVVTRLPISP-LWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVA 442 PE V L S W ++ GL S +M T + + P R++ V + Sbjct: 300 PEAVFFLEHSSRFWITMWLSNCYMTGLRSLIVMMCLNTEVVYNSLPKARKRHTLCVLTFS 359 Query: 443 VFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIG 502 + Y G + +T G + ++ ++ V + + + + + YG KF D+ M+G Sbjct: 360 LIIYTGTIFLSTRIGYSVFKTIESVLNDFCVPFLNTLQLVGVVYFYGITKFRDDVHFMLG 419 Query: 503 RQSKLWVYLWSAMWRIITPAALVFILVFN 531 +S ++ W+ ++ ++ P L +L +N Sbjct: 420 IRSSVY---WNTLY-VLNPLLLGIVLAYN 444 Score = 48.0 bits (109), Expect = 8e-04 Identities = 26/80 (32%), Positives = 44/80 (55%), Gaps = 2/80 (2%) Query: 53 PYLCYNNGGGAFLIPFTVMLV-IAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYG 111 P+L N G LIP ++++ + +P MFMEL+ GQY+ + V++ CPL RG+G Sbjct: 16 PWLLKTNVGILLLIPVQLLVMFLTTIPCMFMELALGQYSNRAVIRVWD-LCPLLRGIGLC 74 Query: 112 MVIVSSIVMLYYNLIIAWTI 131 + + +N I +T+ Sbjct: 75 SFLTFLLYQSSWNKINCFTL 94 >UniRef50_A5ZNA7 Cluster: Transporter; n=4; Bacteria|Rep: Transporter - Ruminococcus obeum ATCC 29174 Length = 495 Score = 70.9 bits (166), Expect = 9e-11 Identities = 60/221 (27%), Positives = 96/221 (43%), Gaps = 15/221 (6%) Query: 209 TNQVLGLSSGI-EETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLV 267 +++V G S + TG + M + +L A+ + L L G++ KV+ L ++V Sbjct: 133 SDEVSGFFSNLMTSTGTMTGWMIVAVLLAFGVCSLGLQNGIERITKVMMICLL---ALIV 189 Query: 268 ILFFRGVTLPGAITGILFYLTPDFSQLANA---QVWGDAAVQIFFALSPAWGGLITLSSY 324 +L VTL GA+ G+ FYL P+ + A V A Q FF LS G + SY Sbjct: 190 VLAVHSVTLDGAMEGVKFYLVPNLDNIRAAGLGNVIFGALSQAFFTLSIGIGAMEIFGSY 249 Query: 325 NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYP 384 +S+ + + + + AGL+I NV G GL FI P Sbjct: 250 MGKECTLAGESINILILDTFVALMAGLIIIPA----CFAFNVEPGA----GPGLVFITLP 301 Query: 385 EVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILD 425 V ++ LW LFF+ + L + A+ E + + +D Sbjct: 302 NVFNQMAGGRLWGALFFLFMSFAALSTVIAVFENILSFAMD 342 Score = 67.7 bits (158), Expect = 9e-10 Identities = 32/112 (28%), Positives = 56/112 (50%), Gaps = 3/112 (2%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 ER + R F NVW+FPY+ GG AF++ + V LV+ GLP++ E Sbjct: 8 ERETFGSRLGFILVSAGCAVGLGNVWKFPYMTGKYGGAAFILIYLVFLVLLGLPILVSEF 67 Query: 85 SFGQYAALGPVAVYNKFCP---LFRGLGYGMVIVSSIVMLYYNLIIAWTIFY 133 + G+ + L ++K P F Y +I + ++M++Y ++ W ++Y Sbjct: 68 AVGRSSRLSTARAFHKLEPEGSNFHKYSYMGMIGNYMLMMFYTMVAGWMMYY 119 >UniRef50_A5ZA96 Cluster: Transporter; n=3; Clostridiales|Rep: Transporter - Eubacterium ventriosum ATCC 27560 Length = 471 Score = 70.9 bits (166), Expect = 9e-11 Identities = 89/351 (25%), Positives = 158/351 (45%), Gaps = 38/351 (10%) Query: 200 RRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTA 259 ++ A+ FTN + SS + G+ LL A +IV+ + KG++ K + Sbjct: 121 KKAVADNCFTNFITSPSS-------VWYGIIFMLLTA-IIVYNGVEKGIERVSKFI-MPV 171 Query: 260 LFPYVVLVILFFRGV-------TLPGAITGILFYLTPDFSQLANA---QVWGDAAVQIFF 309 L VV + +F + T+ + G+ YLTPD S + QV DA Q+FF Sbjct: 172 LLVMVVGIAIFSLTLKTTLDDGTVRTGLQGLKVYLTPDMSGITVQKFLQVSLDAMSQLFF 231 Query: 310 ALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVD 369 +LS + G +IT SY K N + + + +F AG++I + F+ L+ Sbjct: 232 SLSVSMGIMITYGSYVKKDVNLNKAVSQIEIMDTGVAFLAGMMIIPAV-FVFSGLD---- 286 Query: 370 RVVDQGAGLAFIVYPEVVTRLPIS-PLWSILFFVMLLTLGLDSQFALMETVTTAILDRFP 428 + G GL F+ P V R+ ++ + +LFF++ L S +++E++T ++ F Sbjct: 287 -GMSAGPGLMFVSLPNVFFRMGMAGRIVGLLFFLLAGFAALTSCISVLESITANCMELFH 345 Query: 429 NFRQKKGWVVFIVAVFG----YLGGLIF------TTNSGMYWLQLMDKYAANWSVLIIAI 478 R+K V+ I+ + LG IF S L +MD + ++ + I++ Sbjct: 346 TERKKTTGVLSIIYLIATAVIALGYSIFYVEVKLPNGSTGQLLDIMDYISNSFLMPFISL 405 Query: 479 GECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILV 529 ILI WI +++ + S+ +Y + M R I P +V + + Sbjct: 406 LSAILIGWIIKPSWIVEEMELNGKKFSRKKLY--NVMIRYIMPVIMVILFL 454 Score = 69.7 bits (163), Expect = 2e-10 Identities = 31/112 (27%), Positives = 55/112 (49%) Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84 ++ ++G+ F N+WRFPYL +GGG FLI + V+++ G L+ ++ Sbjct: 3 QKSGFSGQIGFVLAAAGSAVGVGNLWRFPYLAAKDGGGLFLIIYLVLVLTVGFTLLTTDI 62 Query: 85 SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTV 136 + G+ + Y ++ LG IV I+M YY +I W + Y+ + Sbjct: 63 AIGRKTGKSAIYAYESMRKKWKFLGVITFIVPVIIMTYYAVIGGWILKYIAI 114 >UniRef50_A2BJD7 Cluster: Na+ dependent transporter; n=2; Desulfurococcales|Rep: Na+ dependent transporter - Hyperthermus butylicus (strain DSM 5456 / JCM 9403) Length = 530 Score = 70.9 bits (166), Expect = 9e-11 Identities = 72/310 (23%), Positives = 138/310 (44%), Gaps = 15/310 (4%) Query: 233 LLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVL--VILFFRGVTLP--GAITGILFYLT 288 LL +IV + +G++ + K++ V+L V L P + G + T Sbjct: 167 LLVITLIVSRRVRRGIEIAAKIMMPILFIEAVILATVSLTLGAPVKPEWSTLKGFEWLWT 226 Query: 289 PDFSQLANAQVWGDAAVQIFFALSPAWGGLI-TLSSYNKFSNNCYIDSLIV-AVSNIATS 346 P+F +L + + + A QIFF LS GG+I +SY + ++ + +L +++ A Sbjct: 227 PNFEKLKDPATFIEGAGQIFFTLSIGIGGIIPNYASYLRREDDLPLSALTTTSLNEFAEV 286 Query: 347 FFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIV-YPEVVTRLP-ISPLWSILFFVML 404 G ++ ++ + LA +V P + L + L L++ +L Sbjct: 287 VLGGSIVIPLLYAFGGPSIIQDIAAGKLSIFLASMVALPPLFNHLGGLGALAGFLWYSLL 346 Query: 405 LTLGLDSQFALMETVTTAILDRFPNFRQKKGWV----VFIVAVFGYLGGLIFTTNSGMYW 460 G+ S A++ +T+ + + R+ W+ VFI VF + G + T Y Sbjct: 347 WFAGITSAIAIVNVLTSMFEEDYGIARRYSAWIAFMMVFITGVFVNIEGAMKTDQLTDY- 405 Query: 461 LQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIIT 520 L L+D YA + +L++A+ E + W++G E+ ++ G + + W + IIT Sbjct: 406 LDLVDFYAGSLLLLVVALFEVVAALWLWGIEESYRELHN--GAYITVPKWYWKYVVGIIT 463 Query: 521 PAALVFILVF 530 P L+ +L + Sbjct: 464 PIYLIIMLAW 473 Score = 54.8 bits (126), Expect = 7e-06 Identities = 38/134 (28%), Positives = 59/134 (44%), Gaps = 14/134 (10%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 R W R N RFP GGGA+LIP+ + LV+ G+PLMF+E + Sbjct: 6 REYWATRIGLILAMAGNAIGLGNFLRFPGKAAAYGGGAYLIPYFIALVLLGIPLMFVEWT 65 Query: 86 FGQYAALG------PVA-------VYNKFCPLFRGLGYGMVIVSSIVML-YYNLIIAWTI 131 G++ L P+ + K F +G + ++ +++ YY II W Sbjct: 66 LGRHGGLHGHGYLTPMLYIVSRNRLTKKNAAAFAIIGGTIAFLTGVMITGYYTNIIGWMG 125 Query: 132 FYMTVSFSSIFYQL 145 +Y T + S F +L Sbjct: 126 YYATAAISGKFAEL 139 >UniRef50_Q31G35 Cluster: Neurotransmitter: sodium symporter (NSS) family transporter; n=2; Gammaproteobacteria|Rep: Neurotransmitter: sodium symporter (NSS) family transporter - Thiomicrospira crunogena (strain XCL-2) Length = 451 Score = 70.5 bits (165), Expect = 1e-10 Identities = 36/123 (29%), Positives = 62/123 (50%), Gaps = 6/123 (4%) Query: 29 WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQ 88 WT + F N+W+FPY+ NGGGAF++ + + +V+ GLP++ E+S G+ Sbjct: 11 WTSQTVFIMAAIGSAVGLGNLWKFPYITGENGGGAFVLVYLLCIVLIGLPILIAEISLGR 70 Query: 89 YA-ALGPVAVYNKF-----CPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIF 142 A P A+ N L+ LG+ V+ +++ +Y++I W + Y S S F Sbjct: 71 AGQANPPQAMANNVKTTGANKLWVFLGFNAVLGGLLILSFYSVIAGWGVAYFIESISGSF 130 Query: 143 YQL 145 + Sbjct: 131 IDM 133 Score = 57.6 bits (133), Expect = 9e-07 Identities = 73/305 (23%), Positives = 132/305 (43%), Gaps = 31/305 (10%) Query: 238 VIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRG-VTLPGAIT-GILFYLTPDFSQLA 295 ++ L + KGV+S G + P +++++L G T GA F P+F+ L Sbjct: 161 LLTVLIVVKGVRS-GIERAINIMMPGLLIILLILLGYATTTGAFAQSFEFLFKPNFAALT 219 Query: 296 NAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFS 355 + V A FF LS +G ++ SY + + SL + V++ + AGLVIFS Sbjct: 220 SESVL-IALGHAFFTLSLGFGTMMVYGSYLPKNYSIVKASLWIVVADTLIALIAGLVIFS 278 Query: 356 VIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFAL 415 ++ + L G GL F P ++ + LFF +++ L S ++ Sbjct: 279 IV--FGNGLEAG------SGPGLLFETLPIAFGQMSGGWFFGTLFFGLVVFAALSSSISM 330 Query: 416 METVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGL--IFTTN--SGMYWL------QLMD 465 +E + + + R+K W ++ F +L GL +F+ N G +L + +D Sbjct: 331 IEPAISWLEQNWGYTRKKAAW---LLGSFAWLLGLGSVFSFNLWKGQTFLEDKTFFESLD 387 Query: 466 KYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALV 525 +N + + + + + W++ C G K W ++S + + I P LV Sbjct: 388 FLTSNIMLPLGGMFTALFVGWVW----TCQQRNDETGMPPK-WSGVYSVIVKWIAP-ILV 441 Query: 526 FILVF 530 FI+ F Sbjct: 442 FIVFF 446 >UniRef50_A6FME6 Cluster: Sodium-dependent transporter family protein; n=1; Roseobacter sp. AzwK-3b|Rep: Sodium-dependent transporter family protein - Roseobacter sp. AzwK-3b Length = 494 Score = 70.1 bits (164), Expect = 2e-10 Identities = 31/124 (25%), Positives = 60/124 (48%), Gaps = 4/124 (3%) Query: 23 EPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFM 82 + + ++G F N+W+FPY+ NGGGAF++ + + ++ G PLMF Sbjct: 45 QSQNAGFSGSMAFILAASGSAVGLGNIWKFPYVTGENGGGAFVLFYLMCILALGAPLMFA 104 Query: 83 ELSFGQYAALGPVAVY----NKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSF 138 E+ G+ GPV + K +GY ++ + + + Y +I W ++Y +++ Sbjct: 105 EIFIGKRGKAGPVDSFKNLGTKAAARAHPVGYIFILTAFVALSVYGVIGGWAVYYTSLAL 164 Query: 139 SSIF 142 + F Sbjct: 165 DNGF 168 Score = 47.2 bits (107), Expect = 0.001 Identities = 55/196 (28%), Positives = 89/196 (45%), Gaps = 17/196 (8%) Query: 244 LCKGVQSSGKVVYFTALFP--YVVLVILFFRGVTLPGA-ITGILFYLTPDFSQLANAQVW 300 + KGV S+G Y T L P +++L+ L +T GA + + F PDF++L + + Sbjct: 205 VAKGV-STGIERYTTILMPLFFMMLLGLTAYALTTSGAGMRSVSFMFNPDFTKLTPSAM- 262 Query: 301 GDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVA---VSNIATSFFAGLVIFSVI 357 +A FF+LS GG++ Y S + + VA V + + AGL+IFSVI Sbjct: 263 AEALGHAFFSLSLGVGGMLVYGQYMPSSPSATPITRSVATIVVVDTLVALCAGLLIFSVI 322 Query: 358 GFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALME 417 H + G GL F+ P + ++L+F +++ L S + +E Sbjct: 323 --FGHGGEAA------GGPGLLFMSLPVAFGEMTGGYYVAVLWFALVVVAALTSGISYLE 374 Query: 418 TVTTAILDRFPNFRQK 433 + A DR R K Sbjct: 375 -IIVAHADRLGMGRAK 389 >UniRef50_Q9HPQ1 Cluster: Sodium-and chloride-dependent transporter; n=3; Halobacteriaceae|Rep: Sodium-and chloride-dependent transporter - Halobacterium salinarium (Halobacterium halobium) Length = 477 Score = 70.1 bits (164), Expect = 2e-10 Identities = 31/125 (24%), Positives = 61/125 (48%), Gaps = 2/125 (1%) Query: 26 RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85 R W R F N+WRFP++ NGG AFL+ + +++ G+P + E Sbjct: 3 RDVWHSRLGFIMAAVGSAVGLGNLWRFPWMTSENGGAAFLLVYLGVVLCVGVPGLLAEFV 62 Query: 86 FGQYAALGPVAVYNKF--CPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFY 143 G+ + PV ++ L+R G+ V+++ +++ +Y+++ W + Y S + ++ Sbjct: 63 IGRRSRRSPVGAFSSLSDSTLWRVFGHLSVVIAVVLLSFYSVVGGWILRYFGASLTGAYF 122 Query: 144 QLPWQ 148 P Q Sbjct: 123 SNPGQ 127 Score = 66.9 bits (156), Expect = 2e-09 Identities = 70/307 (22%), Positives = 127/307 (41%), Gaps = 21/307 (6%) Query: 227 LGMAMCLLA-AWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILF 285 +G + LA +IV + +G++++ K++ + V+L++L TL GA G+ F Sbjct: 139 VGFHLLFLAITGLIVVRGIKRGIENATKLMMPAVV---VLLIVLAAWASTLDGAGAGLAF 195 Query: 286 YLTPDFSQLANAQVWG---DAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSN 342 YL+PD +L A + G AA Q F LS G +IT +SY + D +AV N Sbjct: 196 YLSPDV-ELLEADLLGILPAAAGQALFTLSLGSGTMITYASYLDEERSLAADGAAIAVLN 254 Query: 343 IATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFV 402 AGLV+F ++ L + G G F+ +P +FF Sbjct: 255 TCIGVLAGLVVFPLLFALVGDAGTG-------GPGALFVGLANAFVAVPYGRAVGAVFFA 307 Query: 403 MLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQ 462 ++ + S +++E + ++D + R++ V VF G + G++ Sbjct: 308 VVSLAAISSSISMLELPVSFLVDEYGVSRRRA--TALFVGVFTVTGSAT-ALSPGLF--D 362 Query: 463 LMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPA 522 + + + IG + W+ G + + + G + W ++ P Sbjct: 363 FVAGTLVDLLMTAGLIGFLLFTGWVVG-QNAVTEYELGAGAVASALSTPWLYAVGVVIPV 421 Query: 523 ALVFILV 529 L+F LV Sbjct: 422 FLIFTLV 428 >UniRef50_Q4RXG4 Cluster: Transporter; n=2; Euteleostomi|Rep: Transporter - Tetraodon nigroviridis (Green puffer) Length = 120 Score = 69.7 bits (163), Expect = 2e-10 Identities = 33/100 (33%), Positives = 54/100 (54%), Gaps = 5/100 (5%) Query: 457 GMYWLQLMDKYAANW-SVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAM 515 G Y + + D Y + ++L++A+ + +I WIYG+++FC +I MIG + L Sbjct: 1 GTYIMMIFDHYVCSGPALLLLAVFQSAIIGWIYGSDRFCDNIADMIGYRPHA---LIKYS 57 Query: 516 WRIITPAALVFILVFNWIEYKPASYGH-YVYPMWADAVGW 554 W ITP + L+F + Y P + + YVYP W +GW Sbjct: 58 WMYITPLTCMGTLIFLSVRYTPIKFNNSYVYPWWGYGIGW 97 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.327 0.141 0.455 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 695,872,296 Number of Sequences: 1657284 Number of extensions: 27813359 Number of successful extensions: 81417 Number of sequences better than 10.0: 335 Number of HSP's better than 10.0 without gapping: 313 Number of HSP's successfully gapped in prelim test: 22 Number of HSP's that attempted gapping in prelim test: 79836 Number of HSP's gapped (non-prelim): 739 length of query: 632 length of database: 575,637,011 effective HSP length: 105 effective length of query: 527 effective length of database: 401,622,191 effective search space: 211654894657 effective search space used: 211654894657 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 40 (21.7 bits) S2: 76 (34.7 bits)
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