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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000927-TA|BGIBMGA000927-
PA|IPR000175|Sodium:neurotransmitter symporter
         (632 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q9W1J0 Cluster: Transporter; n=10; Eumetazoa|Rep: Trans...   932   0.0  
UniRef50_Q7QDY5 Cluster: Transporter; n=1; Anopheles gambiae str...   725   0.0  
UniRef50_UPI0000586FC3 Cluster: PREDICTED: similar to IP14091p i...   581   e-164
UniRef50_P48067 Cluster: Sodium- and chloride-dependent glycine ...   562   e-159
UniRef50_UPI00005841AC Cluster: PREDICTED: similar to glycine tr...   555   e-156
UniRef50_Q9Y345 Cluster: Sodium- and chloride-dependent glycine ...   546   e-154
UniRef50_UPI0000E47D36 Cluster: PREDICTED: similar to glycine tr...   537   e-151
UniRef50_UPI0000E49167 Cluster: PREDICTED: similar to solute car...   530   e-149
UniRef50_Q99884 Cluster: Sodium-dependent proline transporter; n...   525   e-147
UniRef50_Q9UN76 Cluster: Sodium- and chloride-dependent neutral ...   517   e-145
UniRef50_A7SXK0 Cluster: Predicted protein; n=2; Nematostella ve...   510   e-143
UniRef50_UPI00015B5244 Cluster: PREDICTED: similar to sodium/shl...   504   e-141
UniRef50_UPI0000E47DA5 Cluster: PREDICTED: similar to solute car...   502   e-140
UniRef50_Q7K4Y6 Cluster: GH22929p; n=8; Pancrustacea|Rep: GH2292...   495   e-138
UniRef50_Q6NND1 Cluster: Transporter; n=14; Endopterygota|Rep: T...   488   e-136
UniRef50_Q0X0E9 Cluster: Amino acid transporter; n=1; Crassostre...   484   e-135
UniRef50_Q1ECY9 Cluster: Transporter; n=2; Danio rerio|Rep: Tran...   479   e-134
UniRef50_P48066 Cluster: Sodium- and chloride-dependent GABA tra...   479   e-133
UniRef50_P48029 Cluster: Sodium- and chloride-dependent creatine...   479   e-133
UniRef50_P31649 Cluster: Sodium- and chloride-dependent GABA tra...   472   e-131
UniRef50_A7S977 Cluster: Predicted protein; n=3; Nematostella ve...   467   e-130
UniRef50_Q4SW66 Cluster: Transporter; n=2; Tetraodontidae|Rep: T...   462   e-128
UniRef50_UPI0000E465AB Cluster: PREDICTED: similar to GABA neuro...   460   e-128
UniRef50_UPI0000E48F61 Cluster: PREDICTED: similar to glycine tr...   460   e-128
UniRef50_Q8WPM9 Cluster: Similar to glycine transporter; n=1; Oi...   459   e-127
UniRef50_P31641 Cluster: Sodium- and chloride-dependent taurine ...   457   e-127
UniRef50_UPI00015B5724 Cluster: PREDICTED: similar to GABA neuro...   454   e-126
UniRef50_UPI0000D5722E Cluster: PREDICTED: similar to solute car...   452   e-125
UniRef50_Q8MZK8 Cluster: Na+/Cl-dependent neurotransmitter trans...   452   e-125
UniRef50_Q20C86 Cluster: Transporter; n=1; Drosophila virilis|Re...   449   e-124
UniRef50_UPI0000587A15 Cluster: PREDICTED: similar to amino acid...   446   e-123
UniRef50_A7S7X6 Cluster: Predicted protein; n=3; Nematostella ve...   444   e-123
UniRef50_UPI000051A316 Cluster: PREDICTED: similar to CG1732-PA,...   443   e-123
UniRef50_Q01959 Cluster: Sodium-dependent dopamine transporter; ...   442   e-122
UniRef50_Q3I1M7 Cluster: Serotonin transporter; n=5; Schistosoma...   442   e-122
UniRef50_Q2ABP4 Cluster: Taurine transporter; n=2; Pteriomorphia...   439   e-121
UniRef50_Q7Q4L1 Cluster: Transporter; n=1; Anopheles gambiae str...   436   e-121
UniRef50_P31645 Cluster: Sodium-dependent serotonin transporter;...   434   e-120
UniRef50_UPI0000E4A7A9 Cluster: PREDICTED: similar to choline tr...   426   e-117
UniRef50_Q5J2D5 Cluster: GABA transporter protein; n=2; Caenorha...   426   e-117
UniRef50_Q03614 Cluster: Sodium-dependent dopamine transporter; ...   425   e-117
UniRef50_P51905 Cluster: Sodium-dependent serotonin transporter;...   424   e-117
UniRef50_UPI0000E47635 Cluster: PREDICTED: similar to high-affin...   418   e-115
UniRef50_UPI00015B4B04 Cluster: PREDICTED: similar to neurotrans...   417   e-115
UniRef50_Q9VLY6 Cluster: Transporter; n=7; Endopterygota|Rep: Tr...   416   e-115
UniRef50_Q4F9L7 Cluster: High-affinity octopamine transporter pr...   409   e-113
UniRef50_UPI000051A91B Cluster: PREDICTED: similar to inebriated...   409   e-112
UniRef50_Q9N3C7 Cluster: Transporter; n=3; Caenorhabditis|Rep: T...   407   e-112
UniRef50_Q7YZB6 Cluster: Sodium and chloride dependent proline t...   405   e-111
UniRef50_A4QNW3 Cluster: Transporter; n=10; Clupeocephala|Rep: T...   401   e-110
UniRef50_Q0PKT4 Cluster: High-affinity octopamine transporter; n...   400   e-110
UniRef50_O76689 Cluster: Sodium-dependent acetylcholine transpor...   397   e-109
UniRef50_Q9VR07 Cluster: Sodium- and chloride-dependent GABA tra...   393   e-108
UniRef50_O17372 Cluster: Sodium:neurotransmitter symporter famil...   388   e-106
UniRef50_Q7K330 Cluster: Transporter; n=11; Diptera|Rep: Transpo...   384   e-105
UniRef50_Q9W4C5 Cluster: Uncharacterized sodium-dependent transp...   384   e-105
UniRef50_UPI00015B40E0 Cluster: PREDICTED: similar to glycine tr...   378   e-103
UniRef50_UPI000069E376 Cluster: Orphan sodium- and chloride-depe...   378   e-103
UniRef50_Q4S8W1 Cluster: Transporter; n=2; Tetraodontidae|Rep: T...   376   e-103
UniRef50_UPI0000D56C9C Cluster: PREDICTED: similar to CG3252-PA;...   376   e-102
UniRef50_UPI0000E4659C Cluster: PREDICTED: similar to GABA trans...   375   e-102
UniRef50_UPI0000E4A90B Cluster: PREDICTED: similar to ENSANGP000...   373   e-101
UniRef50_UPI0000EB09CC Cluster: UPI0000EB09CC related cluster; n...   371   e-101
UniRef50_UPI0000DB6B93 Cluster: PREDICTED: similar to CG3252-PA;...   370   e-101
UniRef50_UPI0000DB6B91 Cluster: PREDICTED: similar to CG3252-PA;...   361   2e-98
UniRef50_A1Z8V9 Cluster: Transporter; n=3; Drosophila melanogast...   359   9e-98
UniRef50_Q4T2D0 Cluster: Transporter; n=3; Euteleostomi|Rep: Tra...   359   1e-97
UniRef50_A1L1P6 Cluster: Transporter; n=3; Danio rerio|Rep: Tran...   357   5e-97
UniRef50_Q17EZ6 Cluster: Sodium/shloride dependent amino acid tr...   356   1e-96
UniRef50_Q4T523 Cluster: Transporter; n=6; Tetraodontidae|Rep: T...   351   3e-95
UniRef50_Q9VSV2 Cluster: Transporter; n=3; Sophophora|Rep: Trans...   350   8e-95
UniRef50_Q4SBR4 Cluster: Transporter; n=8; Euteleostomi|Rep: Tra...   347   4e-94
UniRef50_Q620M8 Cluster: Transporter; n=2; Caenorhabditis|Rep: T...   342   2e-92
UniRef50_Q4RY29 Cluster: Transporter; n=2; Tetraodontidae|Rep: T...   339   1e-91
UniRef50_UPI0000660336 Cluster: Homolog of Homo sapiens "Solute ...   338   3e-91
UniRef50_UPI0000E481CA Cluster: PREDICTED: similar to solute car...   332   1e-89
UniRef50_Q7QGR3 Cluster: Transporter; n=1; Anopheles gambiae str...   332   2e-89
UniRef50_Q9W4S0 Cluster: Transporter; n=14; Eumetazoa|Rep: Trans...   331   3e-89
UniRef50_Q17EZ8 Cluster: Sodium/shloride dependent amino acid tr...   330   5e-89
UniRef50_Q9XUG5 Cluster: Transporter; n=3; Caenorhabditis|Rep: T...   326   1e-87
UniRef50_O76188 Cluster: Potassium coupled amino acid transporte...   322   2e-86
UniRef50_UPI000065F69C Cluster: Homolog of Homo sapiens "Solute ...   315   2e-84
UniRef50_UPI0000DB790C Cluster: PREDICTED: similar to CG5549-PA;...   313   8e-84
UniRef50_UPI0000E4A4BA Cluster: PREDICTED: similar to glycine tr...   312   2e-83
UniRef50_P90890 Cluster: Transporter; n=2; Caenorhabditis|Rep: T...   305   3e-81
UniRef50_Q59DZ2 Cluster: Transporter; n=4; Sophophora|Rep: Trans...   302   2e-80
UniRef50_UPI0000E49DFE Cluster: PREDICTED: similar to taurine tr...   291   4e-77
UniRef50_Q5XIV7 Cluster: Transporter; n=2; Eutheria|Rep: Transpo...   287   6e-76
UniRef50_Q4SBR5 Cluster: Transporter; n=1; Tetraodon nigroviridi...   276   2e-72
UniRef50_A7RFF4 Cluster: Predicted protein; n=1; Nematostella ve...   275   3e-72
UniRef50_Q4RX19 Cluster: Transporter; n=1; Tetraodon nigroviridi...   273   1e-71
UniRef50_O45813 Cluster: Transporter; n=2; Caenorhabditis|Rep: T...   269   2e-70
UniRef50_Q4SR96 Cluster: Transporter; n=4; cellular organisms|Re...   258   3e-67
UniRef50_A6LMJ8 Cluster: Sodium:neurotransmitter symporter precu...   254   7e-66
UniRef50_A1ZBC7 Cluster: Transporter; n=5; Diptera|Rep: Transpor...   250   9e-65
UniRef50_UPI000066095C Cluster: Homolog of Brachydanio rerio "Gl...   246   1e-63
UniRef50_O18288 Cluster: Transporter; n=1; Caenorhabditis elegan...   238   4e-61
UniRef50_Q2AHK9 Cluster: Transporter; n=1; Halothermothrix oreni...   237   9e-61
UniRef50_UPI0000DC2074 Cluster: UPI0000DC2074 related cluster; n...   236   1e-60
UniRef50_Q8IRU1 Cluster: Transporter; n=2; Diptera|Rep: Transpor...   231   4e-59
UniRef50_Q2QAU1 Cluster: Transporter; n=2; Didelphinae|Rep: Tran...   231   6e-59
UniRef50_A1I9V5 Cluster: Sodium-and chloride-dependent transport...   228   3e-58
UniRef50_Q9U2E3 Cluster: Transporter; n=1; Caenorhabditis elegan...   227   9e-58
UniRef50_Q8MZ19 Cluster: Transporter; n=7; Endopterygota|Rep: Tr...   227   9e-58
UniRef50_UPI0000ECA0A4 Cluster: Orphan sodium- and chloride-depe...   225   2e-57
UniRef50_A3QK28 Cluster: Novel protein similar to vertebrate sol...   216   2e-54
UniRef50_Q13032 Cluster: GABA/noradrenaline transporter; n=2; Ho...   213   2e-53
UniRef50_Q58715 Cluster: Uncharacterized sodium-dependent transp...   210   6e-53
UniRef50_UPI0000E460AF Cluster: PREDICTED: similar to inebriated...   209   1e-52
UniRef50_Q9NP91 Cluster: Sodium- and chloride-dependent transpor...   206   2e-51
UniRef50_Q4SBR6 Cluster: Transporter; n=1; Tetraodon nigroviridi...   203   1e-50
UniRef50_Q4AKJ6 Cluster: Transporter; n=4; Bacteria|Rep: Transpo...   200   1e-49
UniRef50_UPI00015A63D4 Cluster: Sodium-dependent dopamine transp...   199   2e-49
UniRef50_Q8TQM2 Cluster: Sodium/chloride-dependent noradrenaline...   196   1e-48
UniRef50_UPI00006CA50D Cluster: Sodium:neurotransmitter symporte...   194   5e-48
UniRef50_Q4SNN5 Cluster: Transporter; n=1; Tetraodon nigroviridi...   185   4e-45
UniRef50_A0UVQ7 Cluster: Transporter; n=5; Clostridium|Rep: Tran...   183   1e-44
UniRef50_Q4RSW5 Cluster: Transporter; n=2; Tetraodontidae|Rep: T...   183   1e-44
UniRef50_A0DZD7 Cluster: Transporter; n=3; Paramecium tetraureli...   181   5e-44
UniRef50_Q1NTI5 Cluster: Transporter; n=2; delta proteobacterium...   180   1e-43
UniRef50_O50649 Cluster: TnaT protein; n=1; Symbiobacterium ther...   173   9e-42
UniRef50_Q9KQI6 Cluster: Sodium-dependent transporter; n=34; Pro...   171   6e-41
UniRef50_A7RZ73 Cluster: Predicted protein; n=1; Nematostella ve...   170   8e-41
UniRef50_UPI0000661366 Cluster: Sodium- and chloride-dependent g...   170   1e-40
UniRef50_Q6PBA3 Cluster: Solute carrier family 6 (Neurotransmitt...   168   3e-40
UniRef50_O44752 Cluster: Sodium:neurotransmitter symporter famil...   167   8e-40
UniRef50_Q695T7 Cluster: Sodium-dependent neutral amino acid tra...   165   3e-39
UniRef50_Q9H2J7 Cluster: Orphan sodium- and chloride-dependent n...   164   7e-39
UniRef50_Q8ENV8 Cluster: Sodium-dependent transporter; n=18; Bac...   161   4e-38
UniRef50_Q1RLZ0 Cluster: Transporter; n=21; Euteleostomi|Rep: Tr...   161   5e-38
UniRef50_Q4SIS1 Cluster: Transporter; n=1; Tetraodon nigroviridi...   161   7e-38
UniRef50_O45915 Cluster: Transporter; n=2; Caenorhabditis|Rep: T...   157   6e-37
UniRef50_A4AIT5 Cluster: Transporter; n=1; marine actinobacteriu...   155   3e-36
UniRef50_O88575 Cluster: Sodium- and chloride-dependent transpor...   155   3e-36
UniRef50_Q8BPL9 Cluster: 0 day neonate eyeball cDNA, RIKEN full-...   154   8e-36
UniRef50_Q9CMU0 Cluster: Transporter; n=3; Pasteurellaceae|Rep: ...   154   8e-36
UniRef50_UPI0001554745 Cluster: PREDICTED: similar to glycine tr...   150   1e-34
UniRef50_UPI00006611F1 Cluster: Homolog of Homo sapiens "Solute ...   147   7e-34
UniRef50_UPI00015B5C87 Cluster: PREDICTED: similar to GA18750-PA...   146   1e-33
UniRef50_A4R7E6 Cluster: Transporter; n=1; Magnaporthe grisea|Re...   146   2e-33
UniRef50_UPI000023D6A8 Cluster: hypothetical protein FG04240.1; ...   145   4e-33
UniRef50_A5UNF8 Cluster: Na+-dependent transporter, SNF family; ...   144   5e-33
UniRef50_Q2NGG4 Cluster: Predicted Na+-dependent transporter; n=...   144   6e-33
UniRef50_UPI0000DB790B Cluster: PREDICTED: similar to CG5549-PA;...   143   1e-32
UniRef50_P44849 Cluster: Uncharacterized sodium-dependent transp...   143   1e-32
UniRef50_A7BDH7 Cluster: Putative uncharacterized protein; n=1; ...   141   4e-32
UniRef50_UPI0001556266 Cluster: PREDICTED: similar to Solute car...   140   8e-32
UniRef50_Q0PHT6 Cluster: High-affinity dopamine transporter prot...   138   5e-31
UniRef50_Q0PHU0 Cluster: High-affinity dopamine transporter prot...   137   7e-31
UniRef50_Q2NGB7 Cluster: Predicted Na+-dependent transporter; n=...   136   2e-30
UniRef50_A7RHB6 Cluster: Predicted protein; n=1; Nematostella ve...   135   4e-30
UniRef50_UPI0000E816B2 Cluster: PREDICTED: similar to solute car...   133   1e-29
UniRef50_Q0UQY0 Cluster: Transporter; n=1; Phaeosphaeria nodorum...   133   2e-29
UniRef50_Q9VLY3 Cluster: Transporter; n=6; Drosophila melanogast...   132   3e-29
UniRef50_A4RP68 Cluster: Transporter; n=2; Sordariomycetes|Rep: ...   131   5e-29
UniRef50_Q0G8L9 Cluster: High-affinity octopamine transporter pr...   129   2e-28
UniRef50_Q6F6P5 Cluster: Transporter; n=2; Acinetobacter|Rep: Tr...   128   4e-28
UniRef50_Q5ARW4 Cluster: Transporter; n=7; Pezizomycotina|Rep: T...   128   6e-28
UniRef50_UPI0000D66570 Cluster: PREDICTED: similar to orphan neu...   126   2e-27
UniRef50_O18300 Cluster: Transporter; n=1; Caenorhabditis elegan...   125   3e-27
UniRef50_Q4TJ95 Cluster: Transporter; n=1; Tetraodon nigroviridi...   124   5e-27
UniRef50_Q4SIS0 Cluster: Transporter; n=2; Tetraodontidae|Rep: T...   124   5e-27
UniRef50_A4VB21 Cluster: Transporter; n=1; Platynereis dumerilii...   124   1e-26
UniRef50_UPI0000EBDBFC Cluster: PREDICTED: similar to orphan neu...   122   3e-26
UniRef50_Q8IGR3 Cluster: Transporter; n=3; Drosophila melanogast...   120   9e-26
UniRef50_Q2VFP2 Cluster: GABA-a receptor 3-like protein; n=1; My...   119   3e-25
UniRef50_UPI000059FF44 Cluster: PREDICTED: similar to Orphan sod...   117   8e-25
UniRef50_Q4SNN3 Cluster: Transporter; n=1; Tetraodon nigroviridi...   117   1e-24
UniRef50_Q17EZ3 Cluster: Sodium/shloride dependent amino acid tr...   111   5e-23
UniRef50_A3CV46 Cluster: Transporter; n=1; Methanoculleus marisn...   109   2e-22
UniRef50_Q9GZN6 Cluster: Orphan sodium- and chloride-dependent n...   102   3e-20
UniRef50_UPI000059FF45 Cluster: PREDICTED: similar to solute car...   100   1e-19
UniRef50_O67854 Cluster: Transporter; n=1; Aquifex aeolicus|Rep:...   100   1e-19
UniRef50_UPI0000F2D4C7 Cluster: PREDICTED: hypothetical protein;...   100   2e-19
UniRef50_UPI0000E49EF2 Cluster: PREDICTED: similar to solute car...   100   2e-19
UniRef50_Q7NXF6 Cluster: Transporter; n=4; Bacteria|Rep: Transpo...    99   3e-19
UniRef50_UPI0000E4A5E3 Cluster: PREDICTED: similar to creatine t...    98   7e-19
UniRef50_A6NZ68 Cluster: Transporter; n=1; Bacteroides capillosu...    98   7e-19
UniRef50_Q2S448 Cluster: Sodium-and chloride-dependent transport...    97   1e-18
UniRef50_A7T6E6 Cluster: Predicted protein; n=1; Nematostella ve...    95   7e-18
UniRef50_Q8U3T4 Cluster: Putative transporter; n=1; Pyrococcus f...    94   9e-18
UniRef50_Q800X8 Cluster: GABA transporter GAT-3; n=9; Euteleosto...    93   2e-17
UniRef50_Q9X7H2 Cluster: Transporter; n=5; Neisseria|Rep: Transp...    93   2e-17
UniRef50_Q6AQ17 Cluster: Probable sodium-dependent transporter; ...    93   3e-17
UniRef50_Q2S4H8 Cluster: Sodium-and chloride-dependent transport...    92   5e-17
UniRef50_P45320 Cluster: Uncharacterized sodium-dependent transp...    92   5e-17
UniRef50_Q5WAS4 Cluster: SNF family sodium-dependent transporter...    91   6e-17
UniRef50_Q5DG59 Cluster: Transporter; n=1; Schistosoma japonicum...    91   8e-17
UniRef50_Q8TSA2 Cluster: Sodium/chloride-dependent transporter; ...    91   8e-17
UniRef50_Q9KDT3 Cluster: Sodium-dependent transporter; n=2; Bact...    90   1e-16
UniRef50_A6TKT9 Cluster: Transporter; n=2; Clostridiaceae|Rep: T...    90   2e-16
UniRef50_Q8F511 Cluster: Transporter; n=4; Leptospira|Rep: Trans...    89   3e-16
UniRef50_UPI0000D57368 Cluster: PREDICTED: similar to CG8485-PA,...    89   4e-16
UniRef50_A5ZSS6 Cluster: Transporter; n=5; Clostridiales|Rep: Tr...    89   4e-16
UniRef50_Q3V0K1 Cluster: Transporter; n=10; Eutheria|Rep: Transp...    88   8e-16
UniRef50_Q1MR94 Cluster: Probable sodium-dependent transporter; ...    87   1e-15
UniRef50_Q6GC30 Cluster: Transporter; n=16; Staphylococcus|Rep: ...    86   2e-15
UniRef50_A3HYF8 Cluster: Sodium-and chloride-dependent transport...    86   2e-15
UniRef50_Q9KG95 Cluster: Sodium-dependent transporter; n=34; Bac...    86   3e-15
UniRef50_Q8A1L9 Cluster: Na+-dependent transporter; n=8; Bactero...    85   4e-15
UniRef50_A7HNE0 Cluster: Sodium:neurotransmitter symporter; n=1;...    85   4e-15
UniRef50_UPI0000DB7B68 Cluster: PREDICTED: similar to CG8291-PA,...    85   5e-15
UniRef50_Q8D8U8 Cluster: Na+-dependent transporter of the SNF fa...    85   7e-15
UniRef50_Q81S42 Cluster: Sodium-dependent transporter; n=13; Bac...    85   7e-15
UniRef50_Q73R42 Cluster: Sodium-dependent transporter, putative;...    85   7e-15
UniRef50_UPI00015B5071 Cluster: PREDICTED: similar to sodium/chl...    84   9e-15
UniRef50_A4A5L0 Cluster: Sodium-and chloride-dependent transport...    84   9e-15
UniRef50_A7HET8 Cluster: Sodium:neurotransmitter symporter precu...    84   1e-14
UniRef50_A6PLC6 Cluster: Sodium:neurotransmitter symporter precu...    84   1e-14
UniRef50_Q5QY70 Cluster: Na+-dependent transporter of the SNF fa...    83   2e-14
UniRef50_Q3A7I2 Cluster: Na+-dependent transporters of the SNF f...    83   2e-14
UniRef50_A6GC50 Cluster: Probable sodium-dependent transporter; ...    83   2e-14
UniRef50_UPI00015563FA Cluster: PREDICTED: hypothetical protein,...    83   3e-14
UniRef50_Q1N557 Cluster: Sodium-dependent transporter, NSS famil...    82   4e-14
UniRef50_A3VN81 Cluster: Sodium-dependent transporter family pro...    82   4e-14
UniRef50_Q8MSR0 Cluster: Transporter; n=3; Sophophora|Rep: Trans...    82   5e-14
UniRef50_Q8RHM5 Cluster: Sodium-dependent tyrosine transporter; ...    81   7e-14
UniRef50_A6PRZ0 Cluster: Transporter; n=2; Bacteria|Rep: Transpo...    81   7e-14
UniRef50_A0RQG4 Cluster: Sodium-and chloride-dependent transport...    81   7e-14
UniRef50_Q9HPQ2 Cluster: Daunorubicin resistance ABC transporter...    81   7e-14
UniRef50_Q5QUN5 Cluster: Na+-dependent transporter of the SNF fa...    80   2e-13
UniRef50_Q7NPX3 Cluster: Transporter; n=5; Proteobacteria|Rep: T...    79   3e-13
UniRef50_Q4LEH9 Cluster: Sodium-dependent transporter; n=1; uncu...    79   3e-13
UniRef50_Q6MBR5 Cluster: Transporter; n=1; Candidatus Protochlam...    79   5e-13
UniRef50_Q3INN0 Cluster: Transporter 55; n=1; Natronomonas phara...    78   8e-13
UniRef50_A4BUI1 Cluster: Probable sodium-dependent transporter; ...    77   1e-12
UniRef50_Q1N1Z9 Cluster: Na+-dependent transporter of the SNF fa...    77   2e-12
UniRef50_Q6MLR2 Cluster: Sodium-dependent serine transporter; n=...    76   3e-12
UniRef50_O25240 Cluster: Sodium-and chloride-dependent transport...    76   3e-12
UniRef50_A6VX44 Cluster: Transporter; n=12; Gammaproteobacteria|...    76   3e-12
UniRef50_Q6I1C4 Cluster: Sodium-dependent transporter, putative;...    75   4e-12
UniRef50_Q0A4P9 Cluster: Transporter; n=1; Alkalilimnicola ehrli...    75   6e-12
UniRef50_Q8E9E5 Cluster: Sodium-dependent transporter, putative;...    75   8e-12
UniRef50_Q83A23 Cluster: Transporter; n=4; Coxiella burnetii|Rep...    74   1e-11
UniRef50_A1HTE8 Cluster: Transporter; n=1; Thermosinus carboxydi...    74   1e-11
UniRef50_Q892Y6 Cluster: Sodium dependent amino acid transporter...    73   2e-11
UniRef50_Q0IBN8 Cluster: Na+-dependent transporter of the SNF fa...    73   2e-11
UniRef50_A7HQJ6 Cluster: Sodium:neurotransmitter symporter precu...    73   2e-11
UniRef50_Q8DBI3 Cluster: Sodium-dependent transporter; n=50; Vib...    73   2e-11
UniRef50_A7CWE7 Cluster: Sodium:neurotransmitter symporter; n=1;...    73   2e-11
UniRef50_Q7M9R0 Cluster: Transporter; n=1; Wolinella succinogene...    72   4e-11
UniRef50_Q9JRT7 Cluster: Sodium-dependent transporter, putative;...    72   5e-11
UniRef50_UPI0000D56C34 Cluster: PREDICTED: similar to solute car...    71   7e-11
UniRef50_A5ZNA7 Cluster: Transporter; n=4; Bacteria|Rep: Transpo...    71   9e-11
UniRef50_A5ZA96 Cluster: Transporter; n=3; Clostridiales|Rep: Tr...    71   9e-11
UniRef50_A2BJD7 Cluster: Na+ dependent transporter; n=2; Desulfu...    71   9e-11
UniRef50_Q31G35 Cluster: Neurotransmitter: sodium symporter (NSS...    71   1e-10
UniRef50_A6FME6 Cluster: Sodium-dependent transporter family pro...    70   2e-10
UniRef50_Q9HPQ1 Cluster: Sodium-and chloride-dependent transport...    70   2e-10
UniRef50_Q4RXG4 Cluster: Transporter; n=2; Euteleostomi|Rep: Tra...    70   2e-10
UniRef50_Q1YQL0 Cluster: Sodium-and chloride-dependent transport...    70   2e-10
UniRef50_Q1QXG5 Cluster: Transporter; n=4; Gammaproteobacteria|R...    69   4e-10
UniRef50_Q1R0J6 Cluster: Transporter; n=2; Gammaproteobacteria|R...    69   5e-10
UniRef50_Q2NAX9 Cluster: Sodium-dependent transporter, NSS famil...    68   9e-10
UniRef50_UPI0000F1FDE3 Cluster: PREDICTED: hypothetical protein;...    67   1e-09
UniRef50_Q604C5 Cluster: Sodium-dependent transporter family pro...    67   1e-09
UniRef50_Q6Q8U6 Cluster: Predicted sodium-dependent transporter;...    67   1e-09
UniRef50_A6W2D9 Cluster: Transporter; n=2; Marinomonas|Rep: Tran...    67   2e-09
UniRef50_A7D6H7 Cluster: Sodium:neurotransmitter symporter; n=1;...    67   2e-09
UniRef50_A7GX85 Cluster: Transcriptional regulator, ModE family;...    66   2e-09
UniRef50_A0Q3N4 Cluster: Transporter; n=4; Clostridiales|Rep: Tr...    66   3e-09
UniRef50_UPI0000E46C11 Cluster: PREDICTED: similar to Na and Cl ...    65   5e-09
UniRef50_Q174T7 Cluster: Sodium/chloride dependent transporter; ...    65   5e-09
UniRef50_Q7VI00 Cluster: Transporter; n=6; Helicobacter|Rep: Tra...    65   6e-09
UniRef50_A1WCH2 Cluster: Transporter; n=9; Proteobacteria|Rep: T...    64   8e-09
UniRef50_Q5QZ24 Cluster: Na+-dependent transporter of the SNF fa...    64   1e-08
UniRef50_Q7VHS6 Cluster: Putative uncharacterized protein; n=1; ...    63   2e-08
UniRef50_A3UE60 Cluster: Sodium-dependent transporter, NSS famil...    63   2e-08
UniRef50_Q1FP51 Cluster: Transporter; n=1; Clostridium phytoferm...    63   3e-08
UniRef50_A6Q1D2 Cluster: Transporter; n=1; Nitratiruptor sp. SB1...    63   3e-08
UniRef50_A5Z8U1 Cluster: Transporter; n=4; Clostridiales|Rep: Tr...    63   3e-08
UniRef50_A0YHQ6 Cluster: Na+-dependent transporter of the SNF fa...    63   3e-08
UniRef50_A4BQ95 Cluster: Sodium-dependent transporter family pro...    62   3e-08
UniRef50_A6EYM5 Cluster: Transporter; n=1; Marinobacter algicola...    62   4e-08
UniRef50_A4J843 Cluster: Transporter; n=1; Desulfotomaculum redu...    61   8e-08
UniRef50_A1EXD4 Cluster: Sodium-dependent symporter family prote...    61   8e-08
UniRef50_Q29N15 Cluster: GA12537-PA; n=1; Drosophila pseudoobscu...    61   8e-08
UniRef50_O83067 Cluster: Sodium-and chloride-dependent transport...    60   2e-07
UniRef50_A5WGE1 Cluster: Transporter; n=5; Gammaproteobacteria|R...    60   2e-07
UniRef50_Q4RDW9 Cluster: Chromosome undetermined SCAF15483, whol...    58   7e-07
UniRef50_A5VFP7 Cluster: Transporter; n=1; Sphingomonas wittichi...    58   9e-07
UniRef50_Q5C106 Cluster: Transporter; n=2; Schistosoma japonicum...    58   9e-07
UniRef50_Q16RP7 Cluster: Sodium/chloride dependent transporter; ...    58   9e-07
UniRef50_Q0BY33 Cluster: Transporter; n=1; Hyphomonas neptunium ...    57   2e-06
UniRef50_A7BZ05 Cluster: Sodium-dependent transporter family pro...    56   2e-06
UniRef50_A5KBP9 Cluster: Amine transporter, putative; n=4; Plasm...    56   2e-06
UniRef50_Q4KIH8 Cluster: Sodium-and chloride-dependent transport...    56   3e-06
UniRef50_A1ZYB1 Cluster: Transporter; n=1; Microscilla marina AT...    56   3e-06
UniRef50_Q14LK2 Cluster: Hypothetical sodium-dependent transport...    55   5e-06
UniRef50_Q2SMN5 Cluster: Na+-dependent transporters of the SNF f...    54   9e-06
UniRef50_Q892Y5 Cluster: Sodium dependent amino acid transporter...    54   1e-05
UniRef50_A1U621 Cluster: Sodium:neurotransmitter symporter precu...    54   2e-05
UniRef50_UPI0000E490C2 Cluster: PREDICTED: similar to sodium/shl...    52   6e-05
UniRef50_UPI0000E47D5A Cluster: PREDICTED: similar to SJCHGC0254...    52   6e-05
UniRef50_Q8IQQ7 Cluster: Transporter; n=7; Diptera|Rep: Transpor...    51   1e-04
UniRef50_Q9V0L3 Cluster: Transporter; n=4; Thermococcaceae|Rep: ...    51   1e-04
UniRef50_Q4TAU1 Cluster: Transporter; n=1; Tetraodon nigroviridi...    50   2e-04
UniRef50_Q4VDZ5 Cluster: Glycerol dehydratase; n=1; Clostridium ...    50   2e-04
UniRef50_A7T318 Cluster: Predicted protein; n=2; Nematostella ve...    50   2e-04
UniRef50_Q60YU4 Cluster: Transporter; n=1; Caenorhabditis briggs...    48   6e-04
UniRef50_O01843 Cluster: Transporter; n=1; Caenorhabditis elegan...    48   6e-04
UniRef50_Q5C0C5 Cluster: SJCHGC08756 protein; n=2; Schistosoma j...    48   8e-04
UniRef50_Q14P41 Cluster: Hypothetical sodium-dependent transport...    48   0.001
UniRef50_A7S7Q6 Cluster: Predicted protein; n=1; Nematostella ve...    48   0.001
UniRef50_A4A5S2 Cluster: Sodium-and chloride-dependent transport...    46   0.002
UniRef50_Q4SNN4 Cluster: Chromosome 15 SCAF14542, whole genome s...    45   0.007
UniRef50_A2BQZ3 Cluster: Integral membrane protein, DUF6; n=5; P...    43   0.022
UniRef50_A7REU1 Cluster: Predicted protein; n=1; Nematostella ve...    43   0.029
UniRef50_Q4S9B0 Cluster: Transporter; n=1; Tetraodon nigroviridi...    42   0.066
UniRef50_Q61SF6 Cluster: Transporter; n=1; Caenorhabditis briggs...    42   0.066
UniRef50_Q9N4S2 Cluster: Putative uncharacterized protein; n=1; ...    40   0.15 
UniRef50_A7AVP9 Cluster: Hypothetcial protein; n=1; Babesia bovi...    40   0.27 
UniRef50_Q7P6C7 Cluster: Sodium-dependent tyrosine transporter; ...    39   0.35 
UniRef50_Q4HES6 Cluster: Sodium-and chloride-dependent transport...    39   0.35 
UniRef50_A4E957 Cluster: Putative uncharacterized protein; n=1; ...    39   0.47 
UniRef50_Q7QFI0 Cluster: ENSANGP00000031294; n=2; Culicidae|Rep:...    38   0.62 
UniRef50_Q8PZM2 Cluster: Putative uncharacterized protein; n=1; ...    37   1.4  
UniRef50_Q5XDS6 Cluster: Branched-chain amino acid transport sys...    36   2.5  
UniRef50_Q23KH0 Cluster: Putative uncharacterized protein; n=1; ...    36   2.5  
UniRef50_Q5LMQ8 Cluster: Membrane protein, putative; n=1; Silici...    36   3.3  
UniRef50_UPI00015B5B52 Cluster: PREDICTED: similar to glycosyltr...    36   4.3  
UniRef50_UPI0000E48A3B Cluster: PREDICTED: similar to sodium/shl...    36   4.3  
UniRef50_UPI0000E473C2 Cluster: PREDICTED: similar to LOC494867 ...    36   4.3  
UniRef50_Q73QV1 Cluster: Integral membrane protein MviN; n=1; Tr...    36   4.3  
UniRef50_Q4PNI2 Cluster: Putative uncharacterized protein; n=1; ...    36   4.3  
UniRef50_A5WG93 Cluster: Cytochrome c oxidase, cbb3-type, subuni...    36   4.3  
UniRef50_Q3IPT6 Cluster: Transporter 43; n=1; Natronomonas phara...    36   4.3  
UniRef50_A6TKN8 Cluster: Putative transmembrane protein; n=1; Al...    35   5.7  
UniRef50_Q2QV81 Cluster: PDR-like ABC transporter, putative, exp...    35   5.7  
UniRef50_Q22970 Cluster: Putative uncharacterized protein F28A12...    35   5.7  
UniRef50_Q6ANB0 Cluster: Probable amino acid ABC transporter, pe...    35   7.6  
UniRef50_Q2B7Y0 Cluster: Putative uncharacterized protein; n=1; ...    35   7.6  
UniRef50_Q1WVA3 Cluster: Type IV prepilin leader peptidase; n=1;...    35   7.6  
UniRef50_Q1F0V4 Cluster: Na+/proline symporter-like; n=1; Clostr...    35   7.6  
UniRef50_Q0CIN1 Cluster: Predicted protein; n=2; Aspergillus|Rep...    35   7.6  

>UniRef50_Q9W1J0 Cluster: Transporter; n=10; Eumetazoa|Rep:
           Transporter - Drosophila melanogaster (Fruit fly)
          Length = 1201

 Score =  932 bits (2306), Expect = 0.0
 Identities = 438/606 (72%), Positives = 484/606 (79%), Gaps = 16/606 (2%)

Query: 21  EIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLM 80
           E E ERG WTGRFDF            NVWRFPYLCYNNGGGAFLIPFT+MLVIAGLPLM
Sbjct: 52  ESEHERGTWTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAFLIPFTIMLVIAGLPLM 111

Query: 81  FMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSS 140
           FMELSFGQYAALGPVAVY +FCPLFRGLG GM++VS+IVMLYYNLIIAWTIFYM  SF+ 
Sbjct: 112 FMELSFGQYAALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAWTIFYMFASFAP 171

Query: 141 IFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALR 200
           +   LPWQNC+  WSTK+C+SY +AD+CEA NGTYYLR C N + +  +NIT LA  AL+
Sbjct: 172 V---LPWQNCEPAWSTKYCFSYAQADQCEATNGTYYLRTCHNATSAAENNITTLALGALK 228

Query: 201 RPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTAL 260
           RPPAEEYF N VLGLS GIEETG I+L +A CL  AW IVFLCLCKGVQSSGKVVYFTAL
Sbjct: 229 RPPAEEYFNNFVLGLSKGIEETGSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTAL 288

Query: 261 FPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLIT 320
           FPYVVLVILF RGVTLPGA TGILFYLTPD+ QLANAQVWGDAAVQIFFALSPAWGGLIT
Sbjct: 289 FPYVVLVILFVRGVTLPGASTGILFYLTPDWKQLANAQVWGDAAVQIFFALSPAWGGLIT 348

Query: 321 LSSYNKFSNNCYI-------------DSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVS 367
           LSSYNKFSNNCY              DSLIVA  NIATSFFAGLVIFS+IGFLAHELNV 
Sbjct: 349 LSSYNKFSNNCYNCGTFELSTKSNSRDSLIVAFCNIATSFFAGLVIFSIIGFLAHELNVD 408

Query: 368 VDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRF 427
           V++VVDQGAGLAFIVYPEVVTRLP+SP+W++LFFVMLLTLGLDSQFALMETVTTAILDRF
Sbjct: 409 VEKVVDQGAGLAFIVYPEVVTRLPVSPVWAVLFFVMLLTLGLDSQFALMETVTTAILDRF 468

Query: 428 PNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWI 487
           PN RQ K WVV  VA+FGY+GGL FTTNSGMYWLQLMDKYAANWSVL+IAI ECILIAWI
Sbjct: 469 PNLRQYKIWVVLSVAIFGYIGGLGFTTNSGMYWLQLMDKYAANWSVLLIAISECILIAWI 528

Query: 488 YGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPM 547
           YG+++F  DIQ MIG++S  W + W  MWR ITPA L+FIL FNW+EYKPA YGHYVYPM
Sbjct: 529 YGSQRFLNDIQGMIGKRSWFWNFFWGIMWRYITPATLLFILFFNWVEYKPAKYGHYVYPM 588

Query: 548 WADAVGWTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWGQAGSTATCLST 607
           WADAVGW                +I   P  L+  ++ + L +PT EWG AG     L  
Sbjct: 589 WADAVGWIVGLLPVLVIFLVAFQEIWRAPMSLSFRDRIKHLLQPTAEWGPAGRPCVNLHA 648

Query: 608 LRVETE 613
            R +++
Sbjct: 649 ERYQSQ 654


>UniRef50_Q7QDY5 Cluster: Transporter; n=1; Anopheles gambiae str.
           PEST|Rep: Transporter - Anopheles gambiae str. PEST
          Length = 558

 Score =  725 bits (1793), Expect = 0.0
 Identities = 332/578 (57%), Positives = 415/578 (71%), Gaps = 26/578 (4%)

Query: 18  LSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGL 77
           +++E   +RG+WTGR+DF            NVWRFPYLCY+NGGGAFLIPFTVMLVIAGL
Sbjct: 1   MNDEALAKRGSWTGRYDFLLSLLGYSVGLGNVWRFPYLCYSNGGGAFLIPFTVMLVIAGL 60

Query: 78  PLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVS 137
           PLMFMELS  QY  LGP  ++ +  P+  G+GYGM++VS +VMLYYN+IIAWT+FYM VS
Sbjct: 61  PLMFMELSLAQYVGLGPAILFKRLAPISEGIGYGMILVSGMVMLYYNVIIAWTVFYMVVS 120

Query: 138 FSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKT 197
           F      LPW+ C+ EW+T +C+SYEE D C A N +YY+  C ++              
Sbjct: 121 FED---PLPWRGCQHEWATVNCFSYEEEDNCLATNRSYYMANCMSR-------------- 163

Query: 198 ALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYF 257
                   E + N  L +S+GIEETG I   +A+CLL AW IVFLCL +GV+SSGKVVYF
Sbjct: 164 --------EQYRNYFLQISAGIEETGMINQRLAICLLVAWAIVFLCLSRGVKSSGKVVYF 215

Query: 258 TALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGG 317
           TALFPYVVL  LF RG+TLPGA  GIL+Y+ PD+ +L  AQ+WGDAAVQIFFALSPAWGG
Sbjct: 216 TALFPYVVLAALFIRGLTLPGAYDGILYYVRPDWDKLRTAQIWGDAAVQIFFALSPAWGG 275

Query: 318 LITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAG 377
           L+TL+SYN+F NNCY D+++VA+SNI TSFFAG VIF++IGFLAHEL+ SVD V+DQGAG
Sbjct: 276 LLTLASYNRFDNNCYRDAIVVAISNILTSFFAGFVIFAIIGFLAHELDTSVDSVIDQGAG 335

Query: 378 LAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWV 437
           LAF+V+PE+V +L +  LWS+LFF MLLTLGLDSQF LMETV TA+LD FP  R++K  V
Sbjct: 336 LAFVVFPELVGKLQMPRLWSVLFFFMLLTLGLDSQFTLMETVVTAVLDTFPALRRRKIAV 395

Query: 438 VFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDI 497
           V  V++ GYLGGLIF TNSGMYW QL DKYAANWSVL+IAI ECIL+ W+YG E+F  +I
Sbjct: 396 VAGVSIVGYLGGLIFVTNSGMYWFQLFDKYAANWSVLLIAIAECILVGWVYGCERFISNI 455

Query: 498 QRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGWTXX 557
           + M+G++SK +   W  +W+ ITPA L+FIL FNW++YKP +YG Y+YP WAD  GW   
Sbjct: 456 EEMLGKRSKWFHRFWVTVWKYITPAMLLFILCFNWLQYKPVAYGRYIYPNWADVFGWIIA 515

Query: 558 XXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEW 595
                         + +        +  R L +P+ EW
Sbjct: 516 LAPFGIAVIVAVKNMSTSSSPFA-WQTIRKLLQPSSEW 552


>UniRef50_UPI0000586FC3 Cluster: PREDICTED: similar to IP14091p
           isoform 1; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to IP14091p isoform 1 -
           Strongylocentrotus purpuratus
          Length = 699

 Score =  581 bits (1434), Expect = e-164
 Identities = 283/552 (51%), Positives = 371/552 (67%), Gaps = 21/552 (3%)

Query: 19  SEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLP 78
           SEE++ ERGNWT   DF            NVWRFPYLCY+NGGGAFLIP+ VML +AG+P
Sbjct: 39  SEEVD-ERGNWTNHLDFLLSCIGYAVGLGNVWRFPYLCYSNGGGAFLIPYLVMLCLAGVP 97

Query: 79  LMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSF 138
           L F+EL+FGQY + GP+  +N   PL RG+GYGMV+VS+IV +YYN+II +++FY   SF
Sbjct: 98  LFFLELAFGQYCSKGPIRAWNA-VPLMRGVGYGMVVVSAIVGIYYNVIITYSLFYFFKSF 156

Query: 139 SSIFYQLPWQNCKAEWSTKHCYSYE----EADECEAQNGTYY--------LRQCFNQSYS 186
           + +   LPW+ C   W+TK C        EAD    +N T            + +N +YS
Sbjct: 157 ARV---LPWEGCHHAWNTKFCSQLVKECIEADGIVTENNTCVPIGNLTDAEMESYNVTYS 213

Query: 187 VSHNITALAK--TALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCL 244
              NIT+      A R+  + E++   +L  S  I + G I   + +CLL AW ++FLCL
Sbjct: 214 DDGNITSYLDPLQASRQSASAEFYKYAMLNESGDIGDPGMISWQLTLCLLFAWSLMFLCL 273

Query: 245 CKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAA 304
            KGV+SSGKVVYFTA FPYVVL ILF RG+TL G I GI F++TP +  L +A+VW DAA
Sbjct: 274 VKGVKSSGKVVYFTATFPYVVLFILFIRGITLEGQIDGIKFFITPQWHLLKDAKVWKDAA 333

Query: 305 VQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHEL 364
           VQIF++LS +WGGLITLSSYNKF NNC+ D++IV ++N ATS FAG VIFS++G +AH L
Sbjct: 334 VQIFYSLSASWGGLITLSSYNKFKNNCFRDAMIVPIANCATSIFAGFVIFSILGHMAHVL 393

Query: 365 NVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAIL 424
           N  V+ V+D+  GLAFI YPE VT LPISPLW+ILFF ML+TLG+DSQF ++ETVTTAI+
Sbjct: 394 NKPVESVIDEQFGLAFIAYPEAVTLLPISPLWAILFFFMLITLGMDSQFCIIETVTTAII 453

Query: 425 DRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILI 484
           D FP+ R+KK  VVF+    G++ GL   T +G YW+ LMDKYAA++++LI  + ECI I
Sbjct: 454 DEFPSLRKKKHLVVFVYCFLGFIFGLSCVTQAGGYWVILMDKYAADFALLIFGLCECIGI 513

Query: 485 AWIYGAEKFCGDIQRMIGRQ--SKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGH 542
            WIYGA +F  DI+ M+G +         W   W  ITP  L+F+L FNW  ++  + G 
Sbjct: 514 GWIYGARRFLNDIRTMLGDRIVDHPLFNFWPLTWCCITPGVLLFVLGFNWATWEFPTAGD 573

Query: 543 YVYPMWADAVGW 554
           Y +P WA  +GW
Sbjct: 574 YEFPTWAHVIGW 585


>UniRef50_P48067 Cluster: Sodium- and chloride-dependent glycine
           transporter 1; n=60; Eukaryota|Rep: Sodium- and
           chloride-dependent glycine transporter 1 - Homo sapiens
           (Human)
          Length = 692

 Score =  562 bits (1388), Expect = e-159
 Identities = 270/576 (46%), Positives = 378/576 (65%), Gaps = 19/576 (3%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           +RGNW  + +F            NVWRFPYLCY NGGGAF+ P+ +ML+  G+PL FMEL
Sbjct: 85  KRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMEL 144

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
           SFGQ+A+ G + V+ +  P+F+G+GYGM++VS+ + +YYN++I    +Y    FSS+ + 
Sbjct: 145 SFGQFASQGCLGVW-RISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYF---FSSMTHV 200

Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPA 204
           LPW  C   W+T  C    +A      NG+       N S+ ++H++        R  P+
Sbjct: 201 LPWAYCNNPWNTHDCAGVLDASNLT--NGSRPAALPSNLSHLLNHSLQ-------RTSPS 251

Query: 205 EEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264
           EEY+   VL LS  I   GE+RL +  CL  +W++VFLCL +GV+SSGKVVYFTA FPYV
Sbjct: 252 EEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYV 311

Query: 265 VLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSY 324
           VL ILF RGVTL GA  GI++YLTP + ++  A+VWGDAA QIF++L+ AWGGLIT++SY
Sbjct: 312 VLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLACAWGGLITMASY 371

Query: 325 NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYP 384
           NKF NNCY DS+I++++N ATS +AG VIFS++GF+A+ L V V RV D G GLAF+ YP
Sbjct: 372 NKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYP 431

Query: 385 EVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPN--FRQKKGWVVFIVA 442
           E +T LPISPLWS+LFF ML+ LGL +QF L+ET+ TAI+D   N    QKK +V   VA
Sbjct: 432 EALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVA 491

Query: 443 VFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIG 502
           V G+L G+  T+ +G+YWL LMD YAA++S+++I+   C+ I +IYG   +  DIQ M+G
Sbjct: 492 VAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGHRNYFQDIQMMLG 551

Query: 503 RQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGWTXXXXXXX 562
               L+   +   WR ++PA + FILVF  I+Y+P +Y HY YP WA A+G+        
Sbjct: 552 FPPPLF---FQICWRFVSPAIIFFILVFTVIQYQPITYNHYQYPGWAVAIGFLMALSSVL 608

Query: 563 XXXXXXXDQICSGPDDLTIMEKARVLARPTEEWGQA 598
                   ++C    D T++++ +   +P+ +WG A
Sbjct: 609 CIPLYAMFRLCRTDGD-TLLQRLKNATKPSRDWGPA 643


>UniRef50_UPI00005841AC Cluster: PREDICTED: similar to glycine
           transporter; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to glycine transporter -
           Strongylocentrotus purpuratus
          Length = 676

 Score =  555 bits (1370), Expect = e-156
 Identities = 278/586 (47%), Positives = 374/586 (63%), Gaps = 23/586 (3%)

Query: 14  SKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLV 73
           SK+   E+   ERGNW+   DF            NVWRFPYLCY+NGGGAFLIP+ VML+
Sbjct: 61  SKSSKKEDENVERGNWSNHLDFILSCVSYAVGLGNVWRFPYLCYSNGGGAFLIPYIVMLL 120

Query: 74  IAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFY 133
            AGLPL F+EL FGQY++ GP++ +    PL +G+GYGMV VS+ V +YYN+II++T+FY
Sbjct: 121 FAGLPLFFLELCFGQYSSSGPISAWRS-APLMKGVGYGMVAVSAWVAIYYNVIISYTMFY 179

Query: 134 MTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITA 193
           M   F S+   LPW  C  EW+T +C     ++  ++ N T       + + +VS  +  
Sbjct: 180 M---FKSMTTSLPWIGCHHEWNTPYC-----SELIDSYNVTT------DGNATVSF-LDP 224

Query: 194 LAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGK 253
           L +   RR P+EEY+ + VL  S  +   G I   +A+CLL AW + F+ L KGV+SSGK
Sbjct: 225 LQE--FRRRPSEEYYRHGVLHDSGDMGSFGYIIWPLALCLLLAWTLEFIFLAKGVKSSGK 282

Query: 254 VVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSP 313
           VVYFTA+FPY+VL IL  RG+TLPG + GILF++ P +  L N +VW DAAVQIFF+LS 
Sbjct: 283 VVYFTAIFPYIVLFILLIRGMTLPGHMDGILFFIKPRWELLKNPKVWKDAAVQIFFSLSA 342

Query: 314 AWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVD 373
           +WGGLITLSSYN+F NNC  D+LIV + N ATS FAG VIFS++G++AHEL   V  VVD
Sbjct: 343 SWGGLITLSSYNRFKNNCMRDALIVPLLNCATSIFAGFVIFSIMGYMAHELKKPVSEVVD 402

Query: 374 QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK 433
           +  GLAFI YPE V RLPISPLW+ LFF ML+TLGL SQ  ++ETV T+I D F N R+K
Sbjct: 403 EQFGLAFIAYPEAVARLPISPLWAFLFFFMLITLGLGSQLCIVETVVTSIADEF-NLRKK 461

Query: 434 KGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKF 493
           K WV+    +  +  GLI  T +G YW+ LMDKYAA++++LI  + ECI + WIYG + F
Sbjct: 462 KIWVLAAYCIIAFFMGLICVTQAGNYWVILMDKYAADFALLIFGMSECIGLGWIYGVKNF 521

Query: 494 CGDIQRMIGRQ--SKLWVYLWSAMWRIITPAALVFILVFNWIEYK-PASYGHYVYPMWAD 550
             DI+ M+G +    +    W   W  +TPA L F+++F+WI ++ P +   Y +P WA 
Sbjct: 522 TNDIRSMLGDRIVDNVLFNWWKLNWCFLTPAVLSFVMLFSWISWEPPMATETYPFPTWAH 581

Query: 551 AVGWTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWG 596
           A+GW                  C    D T  ++ + +A P + WG
Sbjct: 582 ALGWLLILTVIMWIPLYWIYAFCKAKGD-TFRQRLKAMATPEDSWG 626


>UniRef50_Q9Y345 Cluster: Sodium- and chloride-dependent glycine
           transporter 2; n=36; Eumetazoa|Rep: Sodium- and
           chloride-dependent glycine transporter 2 - Homo sapiens
           (Human)
          Length = 797

 Score =  546 bits (1347), Expect = e-154
 Identities = 268/580 (46%), Positives = 374/580 (64%), Gaps = 20/580 (3%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           RGNW+ + DF            NVWRFPYL + NGGGAFLIP+ +ML +AGLP+ F+E+S
Sbjct: 191 RGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVS 250

Query: 86  FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQL 145
            GQ+A+ GPV+V+ K  P  +G G  M+I+S ++ +YYN+II +T+FY+  SF S+   L
Sbjct: 251 LGQFASQGPVSVW-KAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSV---L 306

Query: 146 PWQNCKAEWSTKHCYSYEEA--DECEAQNGTYYLRQCFNQSYSVSH--NITALAKTALRR 201
           PW +C   W+T  C    +   D C   +      Q  N ++ ++   N+T +  T+   
Sbjct: 307 PWGSCNNPWNTPECKDKTKLLLDSCVISDHPKI--QIKNSTFCMTAYPNVTMVNFTSQAN 364

Query: 202 PP----AEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYF 257
                 +EEYF   VL +S+GIE  GEIR  +A+CL  AWVIV+  L KG+++SGKVVYF
Sbjct: 365 KTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLALCLFLAWVIVYASLAKGIKTSGKVVYF 424

Query: 258 TALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGG 317
           TA FPYVVLVIL  RGVTLPGA  GI +++TP + +L +A VW DAA QIFF+LS AWGG
Sbjct: 425 TATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGG 484

Query: 318 LITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAG 377
           LITLSSYNKF NNCY D+LIV  +N ATS FAG VIFSVIGF+A+E  V+++ V DQG G
Sbjct: 485 LITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPG 544

Query: 378 LAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNF-RQKKGW 436
           +AF+VYPE +TRLP+SP W+I+FF+MLLTLGLD+ FA +ET+ T+I D FP + R  K  
Sbjct: 545 IAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPV 604

Query: 437 VVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGD 496
                 +  ++ G    T  G+Y  QL+D YAA+++++IIAI E + I+++YG ++FC D
Sbjct: 605 FTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCED 664

Query: 497 IQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGWTX 556
           I+ MIG Q  ++   W   W  +TP  L FIL F++ +++P +YG Y YP W+  +GW  
Sbjct: 665 IEMMIGFQPNIF---WKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLM 721

Query: 557 XXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWG 596
                         ++   P     +E+ +++  P  +WG
Sbjct: 722 LACSVIWIPIMFVIKMHLAPG--RFIERLKLVCSPQPDWG 759


>UniRef50_UPI0000E47D36 Cluster: PREDICTED: similar to glycine
           transporter 2; n=5; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to glycine transporter 2 -
           Strongylocentrotus purpuratus
          Length = 680

 Score =  537 bits (1326), Expect = e-151
 Identities = 269/600 (44%), Positives = 368/600 (61%), Gaps = 33/600 (5%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           ERGNW+ + DF            NVWRFPYL Y NGGGAFLIP+ +ML  AG+PL F+E+
Sbjct: 45  ERGNWSNKMDFVLSCLGYAVGLGNVWRFPYLAYRNGGGAFLIPYVIMLFFAGIPLFFLEV 104

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
           S GQY +LGP+  + K  PLFRG+GY  ++    V +YYN+II +T++Y  VSF+S    
Sbjct: 105 SLGQYCSLGPIRCW-KSVPLFRGIGYCQMVTVFYVGIYYNIIITYTVYYFGVSFTS---N 160

Query: 145 LPWQNCKAEWSTKHCY-SYEEADE-----CEAQNGTYYLRQCFNQS---YSVSHNITALA 195
           LPW  C   W+TK+CY +Y +  +      +  N   +L     Q+   + V+ N +   
Sbjct: 161 LPWVGCGNSWNTKYCYDNYRQCIDNTSIITDTNNTCVHLESLDEQTLNVFGVARNTSYDE 220

Query: 196 KTALR--------------RPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVF 241
             A+R              +  +EEY+   VL  S  + +T  I   + +CL  +W+IV+
Sbjct: 221 GEAMRYDLSNYTDPLQAERKLASEEYWKGAVLQESDSMNDTDGIIWQLLICLFVSWLIVY 280

Query: 242 LCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWG 301
           LCL +G++SSGKVVYFTA FPYVVLVIL  RG+TLPGA  GI F++TPD S+L++A VW 
Sbjct: 281 LCLVRGIKSSGKVVYFTATFPYVVLVILLVRGLTLPGASEGIRFFVTPDLSKLSDAGVWQ 340

Query: 302 DAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLA 361
           DAA+QIF++LS A GGL TL+SYNKF NNCY+DSL VA++N  TS FAG VIFS++GF+A
Sbjct: 341 DAAIQIFYSLSAAGGGLTTLASYNKFHNNCYVDSLFVAIANCCTSVFAGFVIFSIVGFMA 400

Query: 362 HELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTT 421
           HEL   V+ VV +G GLAF+ YP  V R+PISPLWS+LFF ML+TLGLDSQFA+ME + T
Sbjct: 401 HELQQPVETVVSEGFGLAFVAYPAAVARMPISPLWSVLFFGMLITLGLDSQFAIMENLVT 460

Query: 422 AILDRFP-NFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGE 480
            I D FP   R++K  V+ +  V  +  G    T++G YW+  +D Y A ++ L+ A+ E
Sbjct: 461 MICDEFPQTLRKRKNKVMLVACVSMFFLGFTCITHTGGYWVAHLDSYGAFFNYLVYALLE 520

Query: 481 CILIAWIYGAEKFCGDIQRMIGR--QSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPA 538
           CI IAW YG ++F  DI+ ++G           WS  W   TP  +VF+L FNW+++   
Sbjct: 521 CIAIAWFYGIKRFTNDIRTIVGNGWVDNFTFNWWSVNWSAFTPGLMVFVLFFNWLQWVEP 580

Query: 539 SYGHYVYPMWADAVGWTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWGQA 598
           SY +  +P WA  +GW                +      DL   ++ R ++ PTEEWG A
Sbjct: 581 SY-NGPFPTWAVIIGWLMTTMSLIWIPVVMIFEFLRADGDLA--QRWRAVSNPTEEWGPA 637


>UniRef50_UPI0000E49167 Cluster: PREDICTED: similar to solute
           carrier family 6 member 9; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to solute carrier
           family 6 member 9 - Strongylocentrotus purpuratus
          Length = 606

 Score =  530 bits (1308), Expect = e-149
 Identities = 249/543 (45%), Positives = 353/543 (65%), Gaps = 34/543 (6%)

Query: 17  PLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAG 76
           P ++E +  RG W  + DF            NVWRFP+LCY NGGGAFLIP+ ++L  AG
Sbjct: 59  PYNDEEDQARGKWGSKIDFLLSCVSYAVGIGNVWRFPFLCYQNGGGAFLIPYILILFFAG 118

Query: 77  LPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTV 136
           LPL  +E+SFGQ+  +G + ++ K CP+F+G+GYGM+++  +V +YY +I+A+TIFY+  
Sbjct: 119 LPLFLLEMSFGQFTGVGCLGIW-KICPMFKGIGYGMLVICFLVSIYYQVILAYTIFYLFS 177

Query: 137 SFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAK 196
           S +SI   LPW +C  +W+T +C      D  +  N T+              NI++L  
Sbjct: 178 SLTSI---LPWASCGHQWNTDNC-----TDRMQDSNSTF--------------NISSLLN 215

Query: 197 TALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVY 256
               +PP+EEYF N VLG+S G+ + G ++  +A+CL+AAWVI FLCL KG+++SGKVVY
Sbjct: 216 P---KPPSEEYFYNHVLGISDGVHDLGAVKWKLALCLMAAWVITFLCLIKGIKTSGKVVY 272

Query: 257 FTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWG 316
            T+ FPY+VL ILF RGVTL GA+ GI+FY+ PD S+L   QVW DAA QIFF+L  A+G
Sbjct: 273 LTSTFPYLVLFILFIRGVTLDGAVDGIIFYMKPDLSKLLTPQVWQDAATQIFFSLGVAFG 332

Query: 317 GLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGA 376
            L TLSSYNK+ NNCY D+LIV+V N  TS FAG VIFSV+GF+A +  VSV+ +   G 
Sbjct: 333 SLHTLSSYNKWKNNCYRDALIVSVINCLTSIFAGFVIFSVLGFMAKQAGVSVEDIATSGP 392

Query: 377 GLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRF----PNFRQ 432
           GLAF+ YPE + ++PISPLWSILFF ML  LGL SQF   ETV T + D      P FR+
Sbjct: 393 GLAFVAYPEAIAKMPISPLWSILFFTMLFMLGLGSQFCQFETVNTGLADELEKYSPKFRK 452

Query: 433 KKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEK 492
            K  +   +++  +L GL      GMY + LM+ ++   S++ I + E I+I W YG EK
Sbjct: 453 YKWCITLTMSIVCFLLGLPLVCEGGMYLVNLMNDFSGGLSLVFIGMFETIVITWFYGVEK 512

Query: 493 FCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYG-HYVYPMWADA 551
           +  +++ M+G +     + W A W+ ++P  L+ +++F+   Y+P  YG +Y+YP WA+A
Sbjct: 513 YLDNLEAMLGFRLN---FFWKACWKFVSPVFLLVVIIFSLAMYEPKKYGANYIYPGWAEA 569

Query: 552 VGW 554
           +GW
Sbjct: 570 MGW 572


>UniRef50_Q99884 Cluster: Sodium-dependent proline transporter;
           n=19; Euteleostomi|Rep: Sodium-dependent proline
           transporter - Homo sapiens (Human)
          Length = 636

 Score =  525 bits (1296), Expect = e-147
 Identities = 263/617 (42%), Positives = 381/617 (61%), Gaps = 34/617 (5%)

Query: 12  EKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVM 71
           ++    L  +    RGNWTG+ DF            NVWRFPY  Y NGGGAFL+P+ +M
Sbjct: 23  DQGDVDLDVDFAAHRGNWTGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFLM 82

Query: 72  LVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTI 131
           L I G+PL F+ELS GQ+++LGP+AV+ K  PLF+G G  M+++  +V +YYN+IIA+ +
Sbjct: 83  LAICGIPLFFLELSLGQFSSLGPLAVW-KISPLFKGAGAAMLLIVGLVAIYYNMIIAYVL 141

Query: 132 FYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNI 191
           FY+   F+S+   LPW++C   W+T+ C  +  + +    NG   L            N+
Sbjct: 142 FYL---FASLTSDLPWEHCGNWWNTELCLEHRVSKD---GNGALPL------------NL 183

Query: 192 TALAKTALRRPPAEEYFTNQVLGL--SSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQ 249
           T          P+EEY++  VL +  S GI   GEIR  + +CLL AWVIVFLC+ KGV+
Sbjct: 184 TCTVS------PSEEYWSRYVLHIQGSQGIGSPGEIRWNLCLCLLLAWVIVFLCILKGVK 237

Query: 250 SSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFF 309
           SSGKVVYFTA FPY++L++L  RGVTLPGA  GI FYLTP F  L +++VW +AA+QIF+
Sbjct: 238 SSGKVVYFTATFPYLILLMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEAALQIFY 297

Query: 310 ALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVD 369
           +L   +GGL+T +SYN F  N Y D+ IV + N  TS  AG  IFSV+G+++ EL V VD
Sbjct: 298 SLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQELGVPVD 357

Query: 370 RVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPN 429
           +V   G GLAF+VYP+ +T LP+SP WS LFF MLLTLGLDSQFA +ET+ TA+ D FP 
Sbjct: 358 QVAKAGPGLAFVVYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEFPY 417

Query: 430 F-RQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIY 488
           + R KK     ++ V  YL GLI TT+ GMYWL L+D Y+A++ ++++ I  C+ +  +Y
Sbjct: 418 YLRPKKAVFSGLICVAMYLMGLILTTDGGMYWLVLLDDYSASFGLMVVVITTCLAVTRVY 477

Query: 489 GAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMW 548
           G ++FC DI  M+G +  L+   + A W  ++PA L+ +LV++ ++Y+P+ YG Y +P W
Sbjct: 478 GIQRFCRDIHMMLGFKPGLY---FRACWLFLSPATLLALLVYSIVKYQPSEYGSYRFPPW 534

Query: 549 ADAVGWTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWGQA-GSTATCLST 607
           A+ +G                  +    ++ ++ E+ +  +RP  +WG +     T +  
Sbjct: 535 AELLGILMGLLSCLMIPAGMLVAVLR--EEGSLWERLQQASRPAMDWGPSLEENRTGMYV 592

Query: 608 LRVETELSPPVLLLHGR 624
             +    SP  L++H R
Sbjct: 593 ATLAGSQSPKPLMVHMR 609


>UniRef50_Q9UN76 Cluster: Sodium- and chloride-dependent neutral and
           basic amino acid transporter B; n=21; Tetrapoda|Rep:
           Sodium- and chloride-dependent neutral and basic amino
           acid transporter B - Homo sapiens (Human)
          Length = 642

 Score =  517 bits (1276), Expect = e-145
 Identities = 251/538 (46%), Positives = 350/538 (65%), Gaps = 13/538 (2%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           +RGNW+ + D+            NVWRFPYL Y+NGGGAFLIP+ +ML +AGLPL F+E 
Sbjct: 35  DRGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLPLFFLEC 94

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
           S GQ+A+LGPV+V+ +  PLF+G+G  MV++S  V +YYN+IIA++++YM  SF S   +
Sbjct: 95  SLGQFASLGPVSVW-RILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQS---E 150

Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCF--NQSYSVSHNITALAKTALRRP 202
           LPW+NC + WS K+C        C        +++    N+S+   +N T +  + + +P
Sbjct: 151 LPWKNCSS-WSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGSEIYQP 209

Query: 203 ---PAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTA 259
              P+E+Y+    L  SSG+ ETG I   +A+CLL AW+IV   L KG++SSGKVVYFTA
Sbjct: 210 GQLPSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTA 269

Query: 260 LFPYVVLVILFFRGVTLPGAITGILFYL--TPDFSQLANAQVWGDAAVQIFFALSPAWGG 317
           LFPYVVL+IL  RG TL GA  GI +Y+    +F++L  A+VW DAA QIF++LS AWGG
Sbjct: 270 LFPYVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAWGG 329

Query: 318 LITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAG 377
           L+ LSSYNKF NNC+ D+++V ++N  TS FAG  IFS++G +AH     V +VV  G  
Sbjct: 330 LVALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSGFD 389

Query: 378 LAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWV 437
           LAFI YPE + +LP  P WSILFF MLLTLGLDSQFA +ET+TT I D FP   +K    
Sbjct: 390 LAFIAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPKVMKKMRVP 449

Query: 438 VFI-VAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGD 496
           + +   +  +L GL+  T +G+YW+ L+D + A W +LI AI E + I WIYG  +F  D
Sbjct: 450 ITLGCCLVLFLLGLVCVTQAGIYWVHLIDHFCAGWGILIAAILELVGIIWIYGGNRFIED 509

Query: 497 IQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGW 554
            + MIG +  ++   W A W +ITP  L+ I +++ +++   +YG   YP W  A+GW
Sbjct: 510 TEMMIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPNYGAIPYPDWGVALGW 567


>UniRef50_A7SXK0 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 594

 Score =  510 bits (1258), Expect = e-143
 Identities = 243/575 (42%), Positives = 346/575 (60%), Gaps = 16/575 (2%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           ER  W  + DF            NVWRFPYLCY NGGGAFL+P+ +MLV+ G+P+ FMEL
Sbjct: 5   ERETWGKKADFLLSCIGFAVGLGNVWRFPYLCYANGGGAFLLPYLIMLVLCGMPMFFMEL 64

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
           S GQY +LGP+ V+   CPLFRG+G+  +++S +V +YYN+IIAW ++++ VSF S   +
Sbjct: 65  SAGQYFSLGPIGVWGAICPLFRGIGFASIVISFLVCVYYNVIIAWCLYFLAVSFRS---E 121

Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRR--- 201
           + W++C   W+T +CY+    +      G+       N + + +  + A A  A      
Sbjct: 122 VLWKHCDNWWNTDNCYAGRIPESMSCSLGSGSNNSLVNSTLANATVLAANATNATTECLF 181

Query: 202 -----PPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVY 256
                 P+ E++ N +L LS GI E GEIR  + +CL+ AWV V+ C+ KGV+SSGKVVY
Sbjct: 182 PENQVSPSLEFWENYILRLSDGIGEAGEIRWQILVCLILAWVGVYFCMWKGVKSSGKVVY 241

Query: 257 FTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWG 316
           FTA FPY+VL ILF RGVTLPGA  GI FYL P++ +L + +VW  AA QIF++L   +G
Sbjct: 242 FTATFPYLVLFILFVRGVTLPGADKGIAFYLKPEWHRLKDPKVWVAAATQIFYSLGIGFG 301

Query: 317 GLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGA 376
            L+ + SYNKF NN + D++ +++ N  TS FAG VIFS +GF++H LN  ++ V + G 
Sbjct: 302 SLVAMGSYNKFHNNIFKDAISISLINCGTSVFAGFVIFSTLGFMSHVLNKPIEEVANSGP 361

Query: 377 GLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGW 436
           GLAF+VYPE + ++PISPLW+ILFF M+LTLGLDSQF +ME V T I+D +P  R++K  
Sbjct: 362 GLAFVVYPEAIAQMPISPLWAILFFFMILTLGLDSQFGMMEAVITGIIDEYPVCRKRKEL 421

Query: 437 VVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGD 496
            + +     +L G+   T  G Y L L D  +   S+L +   E + +AWIYGA++F  D
Sbjct: 422 FIAVACFLCFLLGITNVTQGGAYVLNLFDYQSGGVSLLFLGFFETVCLAWIYGADRFSKD 481

Query: 497 IQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGWTX 556
           I+ M+G +   W   W   W+   P  +  I  ++ I ++  SYG Y YP WA+  GW  
Sbjct: 482 IEDMVGSRPAAW---WRFTWKFCAPTVMAGIFFYSIIFWQGVSYGSYKYPQWAEFFGWVI 538

Query: 557 XXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARP 591
                          I   P   T+ E+   L +P
Sbjct: 539 ALSSMLFIPGNAIYMIWKTPG--TLRERVTFLLKP 571


>UniRef50_UPI00015B5244 Cluster: PREDICTED: similar to
           sodium/shloride dependent amino acid transporter,
           partial; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to sodium/shloride dependent amino acid
           transporter, partial - Nasonia vitripennis
          Length = 613

 Score =  504 bits (1243), Expect = e-141
 Identities = 240/574 (41%), Positives = 346/574 (60%), Gaps = 27/574 (4%)

Query: 23  EPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFM 82
           EPERG+W  + +F            NVWRFPYLCY NGGGAFL+P+ +ML++ G+PL FM
Sbjct: 33  EPERGSWASKTEFLLSCAGYAIGIGNVWRFPYLCYRNGGGAFLVPYLLMLLLCGIPLFFM 92

Query: 83  ELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIF 142
           E S GQ+   G + ++ +  PLF+G G+ +VIV+ I  +YYN+II++ + ++ +SF S  
Sbjct: 93  ESSMGQFGGTGCITMF-RMSPLFKGAGFAIVIVNVICTMYYNVIISYPLMFLVMSFKST- 150

Query: 143 YQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRP 202
             LPW++C   W+T  C             G  +  +      +VS  +  +AKT   + 
Sbjct: 151 --LPWESCDNPWNTYGCLKL---------GGEVFAEK------NVSDQMQLIAKT---KT 190

Query: 203 PAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFP 262
           PA+E+F N +L +S  I++ G I   + +C L +W++VFLC+C GV++ GKVVYFTA FP
Sbjct: 191 PADEFFHNHILKISDSIDDIGGIVWPLFICNLISWIVVFLCICNGVKTVGKVVYFTATFP 250

Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322
           +++L +LF RGVTLPGA+ GILFY+ P + +L N +VW DAA+QIFF+L P WGG++ ++
Sbjct: 251 FLILFVLFVRGVTLPGAMDGILFYIMPKWDELLNLKVWADAAIQIFFSLGPGWGGIVNMA 310

Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIV 382
           SYN F NN  +DS++V + N  TS FAG V+FSV+GF+A++  + V  V   G GLAF+ 
Sbjct: 311 SYNPFRNNNRLDSILVPILNCGTSIFAGFVVFSVLGFMAYKTGLPVSTVATGGPGLAFVT 370

Query: 383 YPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVA 442
           YPE +T LP   +W++LFF ML  LG+DS F  +E + +++ D +P+ R++K  V F+  
Sbjct: 371 YPEAITMLPFPQVWAVLFFFMLYLLGMDSCFVQIEAIISSVTDAYPHLRKRKSLVTFVSL 430

Query: 443 VFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIG 502
           +  +LG LIF TN GMY LQ+ D YAA+ SV+ I + E I++ W YG   F  D++ MIG
Sbjct: 431 ILLFLGSLIFVTNGGMYILQMFDWYAASISVISICLVEVIVVGWTYGCGNFVRDVEFMIG 490

Query: 503 RQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGWTXXXXXXX 562
            +   W   W   W+ ITP  L FI V   I     +Y    YP WA AVGW        
Sbjct: 491 EKLHWW---WPLCWKYITPIILSFIFVTTIIFNTRLTYNGIDYPEWAVAVGWCSCLVSML 547

Query: 563 XXXXXXXDQICSGPDDLTIMEKARVLARPTEEWG 596
                    +       T+ EK     RPT +WG
Sbjct: 548 CIPGYAIGYLIFAKG--TLREKLEYGTRPTHKWG 579


>UniRef50_UPI0000E47DA5 Cluster: PREDICTED: similar to solute
           carrier family 6 (neurotransmitter transporter,
           glycine), member 9; n=2; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to solute carrier
           family 6 (neurotransmitter transporter, glycine), member
           9 - Strongylocentrotus purpuratus
          Length = 649

 Score =  502 bits (1237), Expect = e-140
 Identities = 235/583 (40%), Positives = 361/583 (61%), Gaps = 19/583 (3%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           +R +W+ + DF            NVWRFPYLCY NGGGAFL+P+ +ML ++GLPL  MEL
Sbjct: 47  KREHWSNKMDFILSCLGWAVGLGNVWRFPYLCYRNGGGAFLVPYFLMLALSGLPLFLMEL 106

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
             GQ+A+ G + ++    P F+G+G  M +++S+V +YY +IIA+  +Y  VSF+    +
Sbjct: 107 GLGQFASRGVIQIWC-MAPAFKGIGLTMCMINSLVNIYYPVIIAYIFYYFFVSFAR---E 162

Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQ-NGTY-----YLRQCFNQSYSVSHNITALAKTA 198
           LPW+ C   W++++C   +         NGT+     Y    ++ +  + ++  A     
Sbjct: 163 LPWKYCNPLWASENCTDPDSRSNSNGTFNGTFNGTGEYDVSTWSMTTMLPNSTNATNAIE 222

Query: 199 LRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFT 258
             + PA+E++ N VL  SSG+ +TG IR  + +CL   W++ FL L KGV+S GKVVYFT
Sbjct: 223 YAKRPAQEFWDNFVLQRSSGLHDTGVIRWQLLLCLALVWILTFLALVKGVKSVGKVVYFT 282

Query: 259 ALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGL 318
           A FPY+VL IL  RG+TL G++ GIL+Y+ P+FS+L + +VW DAA QIF++L P+WGGL
Sbjct: 283 ATFPYIVLTILLIRGLTLEGSLDGILYYIRPNFSRLKDPRVWKDAAAQIFYSLGPSWGGL 342

Query: 319 ITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGL 378
           +T++SYNKF+NN Y D +I+A+ N +TS FAG VIFSV+GF++ +  + +D+V   G GL
Sbjct: 343 LTMASYNKFNNNFYRDGIIIALLNCSTSIFAGFVIFSVVGFMSFDSGLPIDKVATSGPGL 402

Query: 379 AFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILD----RFPNFRQKK 434
            F+VYPE + R+P +PLWS+LFF M +T+GLDSQF  +ETV + + D      P  R +K
Sbjct: 403 VFVVYPEALARMPFAPLWSVLFFFMFITIGLDSQFVDVETVVSGLYDIVEENIPYMRGRK 462

Query: 435 GWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFC 494
             +  I++   +L G++  T SG+YWL L+D +A+ ++ L++A+ EC++I+++YGA +F 
Sbjct: 463 TLLTGIISFVTFLIGILLVTQSGIYWLTLIDNFASTFTTLVVAVSECLVISYVYGAGRFV 522

Query: 495 GDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASY-GHYVYPMWADAVG 553
            D++ M+G   ++ VY W   W  I P  +VFI +F  + Y+P  Y   Y YP W + +G
Sbjct: 523 EDLKVMLG--YRIPVY-WQIAWMFIAPFVIVFIFIFFCVVYQPLIYDASYTYPQWGETLG 579

Query: 554 WTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWG 596
           W                      +  +I E+      P+E+WG
Sbjct: 580 WLMALSAMIFIPGYFLFFFLFKTEG-SIRERFHTCLSPSEKWG 621


>UniRef50_Q7K4Y6 Cluster: GH22929p; n=8; Pancrustacea|Rep: GH22929p
           - Drosophila melanogaster (Fruit fly)
          Length = 631

 Score =  495 bits (1222), Expect = e-138
 Identities = 252/622 (40%), Positives = 365/622 (58%), Gaps = 32/622 (5%)

Query: 9   GDEEKSKAPLSEE-----IEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGA 63
           G   KSK P   +     I  ER  W+G+ DF            NVWRFPYLCY NGGGA
Sbjct: 5   GHISKSKTPTPHDNDNNSISDERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGA 64

Query: 64  FLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYY 123
           FL+P+ +MLV+ G+PL +MEL+ GQ+   G +  + +  PLF+G+GY +V+++  V  YY
Sbjct: 65  FLVPYGIMLVVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYY 124

Query: 124 NLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQN-GTYY-LRQCF 181
           N+IIAW++ +   SF++    LPW +C   W+T +C  +E  +       G Y  L    
Sbjct: 125 NVIIAWSLRFFFASFTN---SLPWTSCNNIWNTPNCRPFESQNASRVPVIGNYSDLYAMG 181

Query: 182 NQS--YSVSH-NITALAKTALR-----RPPAEEYFTNQVLGL--SSGIEETGEIRLGMAM 231
           NQS  Y+ ++ N ++L  +A+      +  A EYF   +L L  S GI + G I+  MA+
Sbjct: 182 NQSLLYNETYMNGSSLDTSAVGHVEGFQSAASEYFNRYILELNRSEGIHDLGAIKWDMAL 241

Query: 232 CLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDF 291
           CLL  ++I +  L KG+ +SGKVV+FTALFPY VL+IL  RG+TLPG+  GI +YLTP+F
Sbjct: 242 CLLIVYLICYFSLWKGISTSGKVVWFTALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNF 301

Query: 292 SQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGL 351
           S +  A+VW DAA Q+FF+L P +G L+  +SYNK+ NN Y D+L+ +  N ATSF AG 
Sbjct: 302 SAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGF 361

Query: 352 VIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDS 411
           VIFSV+G++AH L V ++ V  +G GL F+VYP  +  +P S  W+++FF+MLLTLGLDS
Sbjct: 362 VIFSVLGYMAHTLGVRIEDVATEGPGLVFVVYPAAIATMPASTFWALIFFMMLLTLGLDS 421

Query: 412 QFALMETVTTAILDRFPNFRQKKGWVVFIVAVFG--YLGGLIFTTNSGMYWLQLMDKYAA 469
            F   E + TA+ D FP  ++ +   +F+  +F   ++ GL   T  G Y+  L+D+YAA
Sbjct: 422 SFGGSEAIITALSDEFPKIKRNR--ELFVAGLFSLYFVVGLASCTQGGFYFFHLLDRYAA 479

Query: 470 NWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILV 529
            +S+L+    E I ++WIYG  +F  DI+ MIG     +   W   WR + P  L+FI V
Sbjct: 480 GYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRY---WQVCWRFVAPIFLLFITV 536

Query: 530 FNWIEYKPASYGHYVYPMWADAVGWTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLA 589
           +  I Y+P +Y  YVYP WA+A+GW                ++ S P  L   ++  +L 
Sbjct: 537 YGLIGYEPLTYADYVYPSWANALGWCIAGSSVVMIPAVAIFKLLSTPGSL--RQRFTILT 594

Query: 590 RPTEEWGQAGSTATCLSTLRVE 611
            P   W    S A  L+ +  E
Sbjct: 595 TP---WRDQQSMAMVLNGVTTE 613


>UniRef50_Q6NND1 Cluster: Transporter; n=14; Endopterygota|Rep:
           Transporter - Drosophila melanogaster (Fruit fly)
          Length = 636

 Score =  488 bits (1203), Expect = e-136
 Identities = 240/534 (44%), Positives = 327/534 (61%), Gaps = 16/534 (2%)

Query: 24  PERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFME 83
           P+RG+W+ + DF            NVWRFPYLCY NGGGAF++P+ + L +AG+P+ FME
Sbjct: 56  PDRGSWSSKMDFILSVVGLAIGLGNVWRFPYLCYKNGGGAFILPYIITLFLAGIPMFFME 115

Query: 84  LSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFY 143
           L+ GQ   +G + V+ K  P+F+G+GY   ++S  + +YY +I+AW +FY    F S+  
Sbjct: 116 LALGQMLTIGGLGVF-KIAPIFKGIGYAAAVMSCWMNVYYIVILAWAVFYF---FMSMRA 171

Query: 144 QLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSH-NITALAKTALRRP 202
            +PW+ C   W+T +C S  E       +    +     +  SVS  NIT+L  T     
Sbjct: 172 DVPWRTCNNWWNTVNCVSQYERKNLHCWDKI--INGTTQKVCSVSALNITSLELTG---- 225

Query: 203 PAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFP 262
           P +E++  + L +S GIEE G IR  +A  LL  W++ + C+ KGV+ +GKVVYFTALFP
Sbjct: 226 PVKEFWERRALQISHGIEEIGNIRWELAGTLLLVWILCYFCIWKGVKWTGKVVYFTALFP 285

Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322
           YV+L IL  RG+TLPGA+ GI FY+ P+FS+L N++VW DA  QIFF+     G L+ L 
Sbjct: 286 YVLLTILLVRGITLPGALEGIKFYIIPNFSKLTNSEVWIDAVTQIFFSYGLGLGTLVALG 345

Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIV 382
           SYNKF+NN Y D+LIV   N +TS FAG VIFSVIGF+AHE    V  V   G GLAF+V
Sbjct: 346 SYNKFTNNVYKDALIVCTVNSSTSMFAGFVIFSVIGFMAHEQQRPVADVAASGPGLAFLV 405

Query: 383 YPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPN-FRQKKGWVVFIV 441
           YP  V +LP SP+WS LFF MLL +GLDSQF  ME   TAI+D +P   R++K   + IV
Sbjct: 406 YPSAVLQLPGSPMWSCLFFFMLLLIGLDSQFCTMEGFITAIIDEWPQLLRKRKEIFIAIV 465

Query: 442 AVFGYLGGLIFTTNSGMYWLQLMDKYA-ANWSVLIIAIGECILIAWIYGAEKFCGDIQRM 500
               YL GL   T  GMY  Q++D YA + + +L +   EC+ I+W YG ++F   I+ M
Sbjct: 466 CALSYLVGLTCITQGGMYIFQILDSYAVSGFCLLWLIFFECVSISWCYGVDRFYDGIKDM 525

Query: 501 IGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGW 554
           IG    +W   W   W + TPA  + +  FN +++ P  Y  Y YP WA A GW
Sbjct: 526 IGYYPTVW---WKFCWCVTTPAICLGVFFFNIVQWTPVKYLDYSYPWWAHAFGW 576


>UniRef50_Q0X0E9 Cluster: Amino acid transporter; n=1; Crassostrea
           gigas|Rep: Amino acid transporter - Crassostrea gigas
           (Pacific oyster) (Crassostrea angulata)
          Length = 662

 Score =  484 bits (1194), Expect = e-135
 Identities = 236/557 (42%), Positives = 345/557 (61%), Gaps = 18/557 (3%)

Query: 8   KGDEEKSKAPLSE-EIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLI 66
           +GD+   ++  S   +E +R  W G+ +F            NVWRFPYLCY NGGGAFLI
Sbjct: 49  EGDDVSQRSTESSGSVEDDRAQWGGKLEFLLTCIGYAVGLGNVWRFPYLCYKNGGGAFLI 108

Query: 67  PFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLI 126
           P+T+ML + GLPL +ME+  GQYA+LGP++++ +  PLF+G+GY MVIVS ++ LYYN+I
Sbjct: 109 PYTIMLALVGLPLFYMEVVLGQYASLGPISIW-RINPLFKGVGYAMVIVSWLIGLYYNVI 167

Query: 127 IAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYS 186
           IA  +FY+  SF+S   +LPW++C  EW+T  C  Y         NGTY     +N +Y 
Sbjct: 168 IAHVLFYLFASFTS---ELPWKHCNNEWNTPSCREYNYQPPSALGNGTYN-STAWNATYV 223

Query: 187 VS----HNIT--ALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIV 240
           V+    HN T   +   +L   P+EEY+ N VLG SSG++E G ++  +A+ LLA+WV V
Sbjct: 224 VNTTFTHNSTYSPIIHHSLITTPSEEYYNNHVLGKSSGLDEIGGVQPYLALTLLASWVTV 283

Query: 241 FLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVW 300
           +L L KG+QS GKVVYFTA+FPY++L++L FRGVTLPGA+ G+++YL PDF++L   +VW
Sbjct: 284 YLVLLKGIQSLGKVVYFTAIFPYLMLIVLMFRGVTLPGAVDGMIYYLKPDFNKLLEPRVW 343

Query: 301 GDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFL 360
            DA  QIF++LS   GG+I +SSYNKF NNCY D++IV V N  TS FAG V     GF+
Sbjct: 344 SDACTQIFYSLSACSGGMIAMSSYNKFKNNCYKDAVIVCVINCGTSVFAGFVYSLYWGFM 403

Query: 361 AHELNVSVDRVVDQGAGLAFIV-YPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETV 419
           A E NV V       +    ++  PE +TR+PI+  WSILFF+M+ TLG  S+F+++E V
Sbjct: 404 AQEKNVPVSGSCRWSSRFGLLLSIPEALTRMPIASFWSILFFIMMATLGFGSEFSIVECV 463

Query: 420 TTAILDRFPNFRQKKGWVVF--IVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIA 477
            +A+ D FP  + ++  ++F  +     +L GL      G+Y L L+D     + +LI+ 
Sbjct: 464 LSALTDVFPQIQPRRANIIFRSVFTAICFLLGLPMVCKGGIYLLNLVDFSVGGFPLLIVG 523

Query: 478 IGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKP 537
           + E + I+WIYG  +F  +I  M+G++   +   W   W+ ++   +   ++ N I Y  
Sbjct: 524 LFELVAISWIYGYNRFSDNIFAMLGKRPTKY---WEICWKFVSLLVIGITVLMNIIMYTE 580

Query: 538 ASYGHYVYPMWADAVGW 554
                  Y  WA ++GW
Sbjct: 581 PELDGQTYSDWAKSLGW 597


>UniRef50_Q1ECY9 Cluster: Transporter; n=2; Danio rerio|Rep:
           Transporter - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 625

 Score =  479 bits (1182), Expect = e-134
 Identities = 250/604 (41%), Positives = 358/604 (59%), Gaps = 41/604 (6%)

Query: 1   MMFQACLKGDEEKSKAPLSEEI-----EPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYL 55
           ++F+  +  +++K K+  +E +       +RGNW+ + ++            NVWRFPYL
Sbjct: 23  VLFKNSVGDEQDKDKSDKAEHVVQNDENSDRGNWSSKREYMLSMIGYAVGLGNVWRFPYL 82

Query: 56  CYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIV 115
            Y +GGGAFLIP+T+ML ++GLPL FME SFGQ+ + GP+ V+ K  P+ +G+G  M++V
Sbjct: 83  AYKHGGGAFLIPYTIMLAVSGLPLFFMESSFGQFCSQGPINVW-KAVPILQGVGITMMLV 141

Query: 116 SSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTY 175
           S+ V +YYN+IIA++I+Y+  SF      LPW       S K+C +        A N + 
Sbjct: 142 STFVAIYYNVIIAYSIYYLFASFQD---PLPW-------SIKNCNTTASNISTAAVNVS- 190

Query: 176 YLRQCFNQSYSVSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLA 235
              Q   QS S                  E+Y+    L  SS ++ETG +   +A+CLL 
Sbjct: 191 -CGQISGQSLS------------------EKYWDEVALQRSSSMDETGPVVWHLALCLLL 231

Query: 236 AWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYL--TPDFSQ 293
           +W++V   L KG++SSGKVVYFTA FPY+VL+IL  RG TL GA  GI FY+    + ++
Sbjct: 232 SWILVGAALFKGIKSSGKVVYFTATFPYIVLLILLIRGATLEGAKDGIEFYIGSQSNLTK 291

Query: 294 LANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVI 353
           LA A+VW DAA QIFF+LS AWGGL+ LSSYNKF NNCY DS++V V+N  TS FAG  I
Sbjct: 292 LAEAEVWKDAATQIFFSLSIAWGGLMALSSYNKFYNNCYQDSIVVCVTNCGTSIFAGFAI 351

Query: 354 FSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQF 413
           FSV+G +AH     V  V D G  LAFI YP+ +++LPISPLWSILFF ML+TLGLDSQF
Sbjct: 352 FSVLGHMAHVYQRPVSEVADAGFALAFIAYPDALSKLPISPLWSILFFFMLITLGLDSQF 411

Query: 414 ALMETVTTAILDRFPN-FRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWS 472
           A +E ++T +LD +P   + K+G V   V +  +L GL   T +G+YW+ L+D ++A W 
Sbjct: 412 AGIEVISTCLLDAYPEVLKSKRGLVTTAVCIILFLLGLPCVTRAGIYWVNLIDTFSAGWI 471

Query: 473 VLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNW 532
           +L+  + E + +  +YG  +F  DI+ MIG +S L+   W A W  ITP  L  IL+++ 
Sbjct: 472 LLVAGLLEVLGLCILYGGNRFIKDIEMMIGTKSSLFWLWWRACWFFITPVVLSIILIWSL 531

Query: 533 IEYKPASYGHYVYPMWADAVGWTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPT 592
             +   +Y    YP W  ++GW                ++C     L   ++ +    PT
Sbjct: 532 YTFTSPTYSSVAYPDWGISLGWCITAFSLMWIPIVAVWKVCKARGGL--WQRIKSACSPT 589

Query: 593 EEWG 596
           E+WG
Sbjct: 590 EDWG 593


>UniRef50_P48066 Cluster: Sodium- and chloride-dependent GABA
           transporter 3; n=182; cellular organisms|Rep: Sodium-
           and chloride-dependent GABA transporter 3 - Homo sapiens
           (Human)
          Length = 632

 Score =  479 bits (1181), Expect = e-133
 Identities = 230/535 (42%), Positives = 330/535 (61%), Gaps = 33/535 (6%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           ERG+W  + +F            NVWRFPYLCY NGGGAFLIP+ V  +  G+P+ F+E 
Sbjct: 49  ERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLET 108

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
           + GQ+ + G +  + K CPLF G+GY   ++ + + +YY +I+AW IFY++  F++   +
Sbjct: 109 ALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTT---E 165

Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPA 204
           LPW  C  EW+T++C  +++ +               N S+    N T+         P 
Sbjct: 166 LPWATCGHEWNTENCVEFQKLNVS-------------NYSHVSLQNATS---------PV 203

Query: 205 EEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264
            E++ ++VL +S GIE  G +R  +A+CLLAAW I + C+ KG +S+GKVVY TA FPY+
Sbjct: 204 MEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYI 263

Query: 265 VLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSY 324
           +L+IL  RGVTLPGA  GI FYL PD S+L++ QVW DA  QIFF+ +   G L  L SY
Sbjct: 264 MLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSY 323

Query: 325 NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYP 384
           N ++NNCY D +++   N  TSF AG  IFSV+GF+A+E  V +  V + G GLAFI YP
Sbjct: 324 NNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYP 383

Query: 385 EVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPN-FRQ--KKGWVVFIV 441
           + VT +P+SPLW+ LFF+ML+ LGLDSQF  +E++ TA++D +P  FR+  ++  ++  +
Sbjct: 384 KAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILAL 443

Query: 442 AVFGYLGGLIFTTNSGMYWLQLMDKYAAN-WSVLIIAIGECILIAWIYGAEKFCGDIQRM 500
           +V  Y  GL+  T  GMY  QL D YAA+   +L +AI ECI I W+YG+ +F  +I+ M
Sbjct: 444 SVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNRFYDNIEDM 503

Query: 501 IGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGH-YVYPMWADAVGW 554
           IG +    +  W   W I+TP     I +F  I+YKP  Y + Y YP W   +GW
Sbjct: 504 IGYRPPSLI-KW--CWMIMTPGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGW 555


>UniRef50_P48029 Cluster: Sodium- and chloride-dependent creatine
           transporter 1; n=43; Euteleostomi|Rep: Sodium- and
           chloride-dependent creatine transporter 1 - Homo sapiens
           (Human)
          Length = 635

 Score =  479 bits (1180), Expect = e-133
 Identities = 234/536 (43%), Positives = 330/536 (61%), Gaps = 28/536 (5%)

Query: 24  PERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFME 83
           P R  WT + DF            NVWRFPYLCY NGGG FLIP+ ++ ++ G+P+ F+E
Sbjct: 50  PPRETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLE 109

Query: 84  LSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFY 143
           +S GQ+   G + V+N  CPLF+GLGY  +++      YY +++AW  +Y+  SF++   
Sbjct: 110 ISLGQFMKAGSINVWN-ICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTT-- 166

Query: 144 QLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPP 203
            LPW  C   W+T  C      ++C             N S +   N+T   + A RR P
Sbjct: 167 -LPWATCGHTWNTPDCVEIFRHEDCA------------NASLA---NLTC-DQLADRRSP 209

Query: 204 AEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPY 263
             E++ N+VL LS G+E  G +   + +CLLA WV+V+ C+ KGV+S+GK+VYFTA FPY
Sbjct: 210 VIEFWENKVLRLSGGLEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPY 269

Query: 264 VVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSS 323
           VVLV+L  RGV LPGA+ GI++YL PD+S+L + QVW DA  QIFF+ +   G L  L S
Sbjct: 270 VVLVVLLVRGVLLPGALDGIIYYLKPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGS 329

Query: 324 YNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVY 383
           YN+F+NNCY D++I+A+ N  TSFFAG V+FS++GF+A E  V + +V + G GLAFI Y
Sbjct: 330 YNRFNNNCYKDAIILALINSGTSFFAGFVVFSILGFMAAEQGVHISKVAESGPGLAFIAY 389

Query: 384 PEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFP---NFRQKKGWVVFI 440
           P  VT +P++PLW+ LFF MLL LGLDSQF  +E   T +LD  P    FR ++   V +
Sbjct: 390 PRAVTLMPVAPLWAALFFFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVAL 449

Query: 441 VAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLI-IAIGECILIAWIYGAEKFCGDIQR 499
                ++  L   T+ GMY  QL D Y+A+ + L+  A  EC+++AW+YGA++F  DI  
Sbjct: 450 CCALCFVIDLSMVTDGGMYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDIAC 509

Query: 500 MIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGH-YVYPMWADAVGW 554
           MIG +   W+  W   W   TP   + I +FN + Y+P  Y + YVYP W +A+GW
Sbjct: 510 MIGYRPCPWM-KW--CWSFFTPLVCMGIFIFNVVYYEPLVYNNTYVYPWWGEAMGW 562


>UniRef50_P31649 Cluster: Sodium- and chloride-dependent GABA
           transporter 3; n=8; Euarchontoglires|Rep: Sodium- and
           chloride-dependent GABA transporter 3 - Mus musculus
           (Mouse)
          Length = 602

 Score =  472 bits (1164), Expect = e-131
 Identities = 233/553 (42%), Positives = 333/553 (60%), Gaps = 39/553 (7%)

Query: 11  EEKSKAPLSEEIEP----ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLI 66
           E K   P  E++E     ER +W  + +F            NVWRFPYLCY NGGGAF I
Sbjct: 13  ETKPVCPAMEKVEEDGTLEREHWNNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFI 72

Query: 67  PFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLI 126
           P+ + L   G+P+ F+E + GQY   G +  + + CP+F G+GY   ++ S++ +YY ++
Sbjct: 73  PYLIFLFTCGIPVFFLETALGQYTNQGGITAWRRICPIFEGIGYASQMIVSLLNVYYIVV 132

Query: 127 IAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYS 186
           +AW +FY+   FSS    LPW +C  EW+T++C  +++A++                   
Sbjct: 133 LAWALFYL---FSSFTTDLPWGSCSHEWNTENCVEFQKAND------------------- 170

Query: 187 VSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCK 246
            S N+T+   T+    P  E++  +VL LS GI+  G +R  + +CLL AW+I + C+ K
Sbjct: 171 -SMNVTSENATS----PVIEFWERRVLKLSDGIQHLGSLRWELVLCLLLAWIICYFCIWK 225

Query: 247 GVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQ 306
           GV+S+GKVVYFTA FPY++LV+L  RGVTLPGA  GI FYL P+ ++L + QVW DA  Q
Sbjct: 226 GVKSTGKVVYFTATFPYLMLVVLLIRGVTLPGAAQGIQFYLYPNITRLWDPQVWMDAGTQ 285

Query: 307 IFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNV 366
           IFF+ +   G L  L SYNK+ NNCY D + + + N +TSF AG  IFS++GF++ E  V
Sbjct: 286 IFFSFAICLGCLTALGSYNKYHNNCYRDCIALCILNSSTSFMAGFAIFSILGFMSQEQGV 345

Query: 367 SVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDR 426
            +  V + G GLAFI YP  V  LP SPLW+  FF M++ LGLDSQF  +E++ TA++D 
Sbjct: 346 PISEVAESGPGLAFIAYPRAVVMLPFSPLWACCFFFMVVLLGLDSQFVCVESLVTALVDM 405

Query: 427 FPN-FRQK--KGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAAN-WSVLIIAIGECI 482
           +P  FR+K  +  ++ IV+V  +  GLI  T  GMY  QL D YAA+   +L +AI E +
Sbjct: 406 YPRVFRKKNRREVLILIVSVISFFIGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFESL 465

Query: 483 LIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYG- 541
            +AW+YGA +F  +I+ MIG   K W  L    W   TPA  +   +F+ I+Y P +Y  
Sbjct: 466 CVAWVYGAGRFYDNIEDMIG--YKPWP-LIKYCWLFFTPAVCLATFLFSLIKYTPLTYNK 522

Query: 542 HYVYPMWADAVGW 554
            Y YP W DA+GW
Sbjct: 523 KYTYPWWGDALGW 535


>UniRef50_A7S977 Cluster: Predicted protein; n=3; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 605

 Score =  467 bits (1151), Expect = e-130
 Identities = 224/577 (38%), Positives = 345/577 (59%), Gaps = 27/577 (4%)

Query: 21  EIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLM 80
           E E  R  W+ + +F            NVWRFPYLCY NGG  FLIP+ +ML++ G+PL 
Sbjct: 34  EEEQTRDKWSSKAEFMLSSLGYCVGFGNVWRFPYLCYKNGGATFLIPYFIMLIVNGIPLF 93

Query: 81  FMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSS 140
           F+EL+ GQ+ + G + V+   CPL +G+GY + ++S +  +YY +I+AWT +Y+ +SF +
Sbjct: 94  FLELAIGQWFSSGVIGVWKSICPLLKGIGYAICMISYLCCIYYIVILAWTFYYLFMSFQA 153

Query: 141 IFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALR 200
           +   +PW+ C   W+TK C +    D          L  C      +  N TA   +   
Sbjct: 154 V---VPWKTCDNPWNTKFCRAKRSGD---------LLLNC--TELDLPQNCTAKPTS--- 196

Query: 201 RPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTAL 260
             P+ E+++N VL ++  I + G++R  +    + +W++V+ CL KG++SSGKVVYFTA 
Sbjct: 197 --PSGEFWSNNVLEMTEDISDFGDMRWPLFGTFILSWIVVYFCLFKGIKSSGKVVYFTAT 254

Query: 261 FPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLIT 320
           FP++VL IL  RG TL G++ G+++YL PD+ +LA+ QVW  AA QI+++L   +G LIT
Sbjct: 255 FPFIVLFILMIRGATLEGSLDGVIYYLNPDWERLADPQVWIYAATQIYWSLGVGFGALIT 314

Query: 321 LSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAF 380
             SYNKF+NN + D+L+++++N +TSFFAG V+FSV+GF+A  L+ +V +V   G GLAF
Sbjct: 315 FGSYNKFNNNVHKDALVISIANCSTSFFAGFVVFSVLGFMALTLDTTVAKVATSGPGLAF 374

Query: 381 IVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFP---NFRQKKGWV 437
           + YPE ++++P+S LW++LFF ML+TLGLDSQFA +E V TAI+D +P     + +K   
Sbjct: 375 VAYPEAISQMPVSTLWAVLFFFMLITLGLDSQFATIEAVITAIVDEYPWVRGTKWRKPVF 434

Query: 438 VFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDI 497
           V I+ +   + GL      GM+   LMD   A  S+LI+A+ E I I WIYG ++F  D+
Sbjct: 435 VLILCISLCILGLPCVFQGGMWIFNLMDYQVAGLSLLIVALLEIITIGWIYGVDRFSDDV 494

Query: 498 QRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGWTXX 557
           + M GR+   W   +   W+ ++P   + I++ N I++K   Y    YP WA+ +GW   
Sbjct: 495 EYMTGRRPMRW---FRICWKYVSPLCTLAIILANLIQWKGVKYNGKPYPGWAELIGWMLM 551

Query: 558 XXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEE 594
                        +I       T+ E+   L +P EE
Sbjct: 552 LSSVLMIPAFAIHEIYKRSG--TLRERITFLLKPDEE 586


>UniRef50_Q4SW66 Cluster: Transporter; n=2; Tetraodontidae|Rep:
           Transporter - Tetraodon nigroviridis (Green puffer)
          Length = 667

 Score =  462 bits (1138), Expect = e-128
 Identities = 230/546 (42%), Positives = 326/546 (59%), Gaps = 23/546 (4%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           ER  WT + DF            NVWRFPYLCY NGGG FLIP+ + + I G+P+ F+E+
Sbjct: 60  ERETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYLLFVFIGGIPVFFLEI 119

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
           + GQ+   G V+ +N   PLF+GLG   +++      YY +I+ W ++++  SF++    
Sbjct: 120 ALGQFMKQGGVSAWN-IAPLFKGLGLASMVIVFFCNTYYIMILVWGLYFLFHSFTN---P 175

Query: 145 LPWQNCKAEWSTKHC--------YSYEEADECEAQNGTYYLRQC--FNQSYSVSHNITAL 194
           LPW  C   W+T++C        ++   A    A   +  L      N S + S   ++ 
Sbjct: 176 LPWATCGHPWNTQNCTQDFRRACHNRSAALSWSAVTPSSLLSSTSLVNLSSAQSFLNSSC 235

Query: 195 AKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKV 254
            +T   R P  E++  +VL LS G+ E G I   M +CL+A W+IV+ C+ KGV+S+GKV
Sbjct: 236 TETEGLRSPVIEFWERKVLRLSGGLHELGNISYEMVLCLIATWIIVYFCMWKGVKSTGKV 295

Query: 255 VYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPA 314
           VYFTALFPYV+LV+L   G TLPGA+ GI++YL PD+S+L  AQVW DA  QIFF+ +  
Sbjct: 296 VYFTALFPYVILVVLLAHGATLPGALDGIIYYLKPDWSKLGEAQVWIDAGTQIFFSYAIG 355

Query: 315 WGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQ 374
            G L  L SYN+F NNCY D+ I+A+ N  TSFFAG V+FSV+GF+A E  V + +V + 
Sbjct: 356 LGALTALGSYNRFHNNCYRDAFILAIINSGTSFFAGFVVFSVLGFMATEQGVDISKVAES 415

Query: 375 GAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPN----F 430
           G GLAFI YP+ VT +P++PLW+ LFF MLLTLGLDSQF  +E + T I+D  P      
Sbjct: 416 GPGLAFIAYPKAVTLMPLAPLWAALFFFMLLTLGLDSQFVGVEGLITGIMDMLPPKSVLG 475

Query: 431 RQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLI-IAIGECILIAWIYG 489
             ++  V  I  +  +L  +   T  GMY  QL D Y+A+   L+  A  EC++IAW+YG
Sbjct: 476 SLRREVVAAICCIICFLIDISMVTEGGMYVFQLFDYYSASGITLLWQAFWECVVIAWVYG 535

Query: 490 AEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGH-YVYPMW 548
           A++F  D+ RMIG     ++      W  ITP   V + +F+ + +KP +Y   Y YP W
Sbjct: 536 ADRFMDDVARMIGYHPLPYM---KCCWSYITPLVCVGVFLFHVVNFKPLTYNTVYTYPWW 592

Query: 549 ADAVGW 554
            + +GW
Sbjct: 593 GEMLGW 598


>UniRef50_UPI0000E465AB Cluster: PREDICTED: similar to GABA
           neurotransmitter transporter; n=2; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to GABA
           neurotransmitter transporter - Strongylocentrotus
           purpuratus
          Length = 659

 Score =  460 bits (1135), Expect = e-128
 Identities = 242/610 (39%), Positives = 350/610 (57%), Gaps = 28/610 (4%)

Query: 9   GDEEKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPF 68
           GD EK      E  E ER  W  + DF            NVWRFPYL + NGGGAFLIP+
Sbjct: 21  GDLEKKGEIEGENAEVEREGWDNKMDFIMICIGFAVGLGNVWRFPYLVFKNGGGAFLIPY 80

Query: 69  TVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIA 128
              L+I+G+P+ F+E+S GQ   +G ++V+  + P+ +G+G+    +++I+  YY +I A
Sbjct: 81  LKSLIISGVPIFFLEISIGQALQVGGISVWEVY-PILKGVGFAGATIAAIMCTYYIVICA 139

Query: 129 WTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYE-EADE--CEAQNGTYYLRQCFNQSY 185
           W+ FY+   FSS    LPW +C   W+  +C     + D+  C A  G +    C   S 
Sbjct: 140 WSFFYL---FSSFTTTLPWGDCDNSWNNLYCNDPALQGDDANCSAPTGFF----CTTNS- 191

Query: 186 SVSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLC 245
           S+  N+T          PA++++  + LG+S GI+E G +R  +  CL  AWV+V+ C+ 
Sbjct: 192 SIYINLTE------GESPAQQFWEKRALGISDGIDEVGSLRWDLVGCLALAWVVVYFCIW 245

Query: 246 KGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAV 305
           KGV+ +GK+V+FTAL PYV+L+ L  RG+TLPGA  GI FY+TPD+ +L +  VW DAA 
Sbjct: 246 KGVKQTGKIVWFTALVPYVILLALLIRGLTLPGASEGIKFYVTPDWERLKSPTVWIDAAT 305

Query: 306 QIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELN 365
           QIFF+ S   G LI+L SYNK  NN   D+LIV V N  TS FAG VIF+++GF+A +  
Sbjct: 306 QIFFSYSVGIGSLISLGSYNKVRNNAMFDTLIVGVVNAGTSLFAGFVIFAILGFMADQQG 365

Query: 366 VSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILD 425
           V V  VVD+G GL F+ YP  V  +P  P WS++FF ML+ LGLDSQFA++E + T+++D
Sbjct: 366 VPVKDVVDEGPGLTFVAYPTAVYYMPGGPAWSVIFFAMLIMLGLDSQFAILEGLVTSLMD 425

Query: 426 RFPNFRQKKGWVVFIVAV--FGYLGGLIFTTNSGMYWLQLMDKYAANWSVLI-IAIGECI 482
            FP F  ++   VF+V +    +L GL+  T  GMY+ QLMD Y A+   L+ +A  ECI
Sbjct: 426 EFPQFNLRQNRAVFLVIICFVDFLLGLLCVTEGGMYFFQLMDTYGASGMCLLWVAFWECI 485

Query: 483 LIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYG- 541
            I++ YG +KF   I   +G       + W   W  + PA  + I +F+ I+Y+PA YG 
Sbjct: 486 AISYGYGIKKFYYIISDNMGFTPG---WYWPLCWAGLAPAVSLGIFLFSLIDYQPAKYGE 542

Query: 542 HYVYPMWADAVGWTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWGQAGST 601
           +Y YP+W + +GW                   + P   T ME+  ++  P  +  + G  
Sbjct: 543 NYYYPIWGEILGWMMAIVSMQWIPVYAIYVFLTTPG--TFMERLHIITSPRIQPAKPGKL 600

Query: 602 ATCLSTLRVE 611
               ST+ VE
Sbjct: 601 ED-ESTISVE 609


>UniRef50_UPI0000E48F61 Cluster: PREDICTED: similar to glycine
           transporter type 2b, partial; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to glycine
           transporter type 2b, partial - Strongylocentrotus
           purpuratus
          Length = 542

 Score =  460 bits (1133), Expect = e-128
 Identities = 214/540 (39%), Positives = 335/540 (62%), Gaps = 38/540 (7%)

Query: 64  FLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYY 123
           FLIP+ +ML +AG+PLMF+EL+FGQY   GP+ ++ K CPLF G+G+ MV++S +V +YY
Sbjct: 2   FLIPYFIMLFLAGMPLMFLELAFGQYGGEGPITIW-KACPLFAGIGWAMVMISGMVAIYY 60

Query: 124 NLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQ 183
           N+I+AWT  +   SF+S   ++PW+ C   W+T         D C+  +           
Sbjct: 61  NIIMAWTALFFVRSFTS---EVPWKTCNNTWNT---------DACQENSSV--------- 99

Query: 184 SYSVSHNITALAKTALRRPPAEEYFTNQVLGLSS-GIEETGEIRLGMAMCLLAAWVIVFL 242
           +  +  NIT        + PA+E++ N VL +    +++ G ++  + MCLL +W+++F 
Sbjct: 100 AMEMGLNIT--------KRPAQEFYYNYVLDVDGHNLDDMGSMKWELVMCLLFSWIVIFC 151

Query: 243 CLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGD 302
           C+CK V+SSGKVVYFTA FPY++L IL  RGVTLPGA  GI +YL+P + +L    VWG 
Sbjct: 152 CICKSVKSSGKVVYFTATFPYIILTILLIRGVTLPGASIGIDYYLSPRWEKLKETAVWGA 211

Query: 303 AAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAH 362
           AA QIF++L PAWGG++T SSYNKF+NNC ID++ + + N  +SF+AG V+FS +GF+++
Sbjct: 212 AATQIFYSLGPAWGGVLTFSSYNKFNNNCLIDAICIPIINCLSSFYAGFVVFSTLGFMSY 271

Query: 363 ELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTA 422
           +  +S+D V  +G GL F  YPE ++++P +P WSILFF M   +GLD+QF ++ETV + 
Sbjct: 272 KTGISIDNVAVKGPGLVFETYPEAISQMPAAPFWSILFFFMFFLVGLDTQFGMVETVVSG 331

Query: 423 ILDRFPNFRQKKGWV-VFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGEC 481
           + D +PN  +K G +   +V V  +L GL   +  G+Y  +L++ Y+   S++++ + EC
Sbjct: 332 LTDYYPNHLRKHGTLTALVVCVVFFLLGLPMASQGGIYMFELINWYSCWISLMLVGVFEC 391

Query: 482 ILIAWIYGAEKFCGDIQRMIGRQSKL------WVYLWSAMWRIITPAALVFILVFNWIEY 535
           + +A+ YG  +F  DI+RMI   + +       +Y +S+ W +ITP+ +VFI VF  + Y
Sbjct: 392 VAVAYFYGVRRFTNDIRRMIADYTWMTPVVTPLLYWYSSCWLVITPSIIVFISVFGMVNY 451

Query: 536 KPASYGHYVYPMWADAVGWTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEW 595
            P  +G YVYP W++ +GW                ++    +  T  ++   L RPT +W
Sbjct: 452 VPVYFGDYVYPKWSEMLGWLMAVVPLFTIPLVMIIKLFFASEGETYAQRFMFLLRPTPQW 511


>UniRef50_Q8WPM9 Cluster: Similar to glycine transporter; n=1;
           Oikopleura dioica|Rep: Similar to glycine transporter -
           Oikopleura dioica (Tunicate)
          Length = 674

 Score =  459 bits (1131), Expect = e-127
 Identities = 220/536 (41%), Positives = 329/536 (61%), Gaps = 22/536 (4%)

Query: 24  PERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFME 83
           P R +W  + +F            N+WRFPYL Y NGGGAFLIP+ + LV+ GLP+   E
Sbjct: 77  PGRQSWGNKIEFMLSMVGYAVGLGNIWRFPYLTYKNGGGAFLIPYLICLVLCGLPIFLFE 136

Query: 84  LSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFY 143
           ++ GQ+ + GP+  +N   P+F+G+GY MV VS+I+  YYN+II++T+ Y+  SF +   
Sbjct: 137 VALGQFCSQGPIKAFNGV-PIFKGIGYAMVAVSTIIGCYYNVIISYTLRYLFESFQAFST 195

Query: 144 -QLPWQNCKAEWSTKHCYSYEEADECEA--QNGTYYLRQCFNQSYSVSHNITALAKTALR 200
            +LPW NC   W+ + C      + C +   NGT  +      +++             R
Sbjct: 196 GELPWANCDNSWNDEKCMDVGRLNRCRSIQANGTLEVPAMCQLNHTN------------R 243

Query: 201 RPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTAL 260
             P+++YF N +L +S  IE+ G  +  + + L  ++ I+F+CL KG+QS+GK VY T+ 
Sbjct: 244 EAPSQQYFENHILEMSDSIEDVGLPKADLVLYLAISYAILFICLAKGIQSTGKAVYITST 303

Query: 261 FPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLIT 320
           FPYVVL  L   G+T  G++ GI ++LTP++ +L +  VW DAA QIFF+LS +WGGLIT
Sbjct: 304 FPYVVLTTLLIVGLTKDGSLNGIKYFLTPEWERLKDMSVWKDAATQIFFSLSASWGGLIT 363

Query: 321 LSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAF 380
           L+SYN+F NN   D+LIV ++N ATS FAGL IFS +GF+AH + V V+ V  QG GLAF
Sbjct: 364 LASYNEFDNNIVRDTLIVVLTNSATSIFAGLTIFSYLGFMAHSMGVEVEDVARQGPGLAF 423

Query: 381 IVYPEVVTRLPI-SPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVF 439
           I YPE +T++   S +WS+LFF MLL LGL + FA M T+ T   D FP  R+++     
Sbjct: 424 IAYPEALTQISTGSIVWSVLFFTMLLMLGLSTMFATMNTIITCCSDAFPQLRKRQASFTA 483

Query: 440 IVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQR 499
           ++ VF +L G+  TT +G+Y L L D +  ++++L+I++ E + I +IYG + FC DIQ 
Sbjct: 484 VLCVFLFLLGIPMTTRAGLYILTLFDDFGGSYALLVISVAEMVSICFIYGLDNFCSDIQI 543

Query: 500 MIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWAD--AVG 553
           MI R   ++   W   W+ ++P  L  + +     +K ++ G+YVYP W +  AVG
Sbjct: 544 MIKRPVGMF---WRICWKFVSPVLLTAVFIAVLANWKVSTLGNYVYPNWTNYPAVG 596


>UniRef50_P31641 Cluster: Sodium- and chloride-dependent taurine
           transporter; n=17; Gnathostomata|Rep: Sodium- and
           chloride-dependent taurine transporter - Homo sapiens
           (Human)
          Length = 620

 Score =  457 bits (1127), Expect = e-127
 Identities = 232/586 (39%), Positives = 330/586 (56%), Gaps = 34/586 (5%)

Query: 24  PERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFME 83
           P+R  W+ + DF            NVWRFPYLCY NGGGAFLIP+ + L  +GLP+ F+E
Sbjct: 39  PQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLE 98

Query: 84  LSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFY 143
           +  GQY + G +  + K CPLF G+GY  V++ S++ +YY +I+AW  +Y+  SF     
Sbjct: 99  IIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQK--- 155

Query: 144 QLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPP 203
           +LPW +C   W+T HC                 +     ++ SV   I++   T+    P
Sbjct: 156 ELPWAHCNHSWNTPHC-----------------MEDTMRKNKSVWITISSTNFTS----P 194

Query: 204 AEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPY 263
             E++   VL LS GI+  G ++  +A+CLL  W++ F C+ KGV+S+GKVVYFTA FP+
Sbjct: 195 VIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPF 254

Query: 264 VVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSS 323
            +L++L  RG+TLPGA  GI FYL PD ++L + QVW DA  QIFF+ +   G + +L S
Sbjct: 255 AMLLVLLVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGS 314

Query: 324 YNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVY 383
           YNK+  N Y D +++   N  TSF +G  IFS++GF+A E  V +  V + G GLAFI Y
Sbjct: 315 YNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAY 374

Query: 384 PEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGW--VVFI- 440
           P+ VT +P+   WSILFF+MLL LGLDSQF  +E   T+++D +P+F  +KG+   +FI 
Sbjct: 375 PKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSF-LRKGYRREIFIA 433

Query: 441 -VAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLI-IAIGECILIAWIYGAEKFCGDIQ 498
            V    YL GL   T  GMY  QL D YAA+   L+ +A  EC +IAWIYG +     I+
Sbjct: 434 FVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIE 493

Query: 499 RMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGH-YVYPMWADAVGWTXX 557
            MIG +   W+      W +ITP   V   +F+ ++Y P +Y   YVYP WA  +GW+  
Sbjct: 494 DMIGYRPGPWM---KYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLA 550

Query: 558 XXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWGQAGSTAT 603
                        ++C       +  K  +  R    W      AT
Sbjct: 551 LSSMLCVPLVIVIRLCQTEGPFLVRVKYLLTPREPNRWAVEREGAT 596


>UniRef50_UPI00015B5724 Cluster: PREDICTED: similar to GABA
           neurotransmitter transporter-1B; n=1; Nasonia
           vitripennis|Rep: PREDICTED: similar to GABA
           neurotransmitter transporter-1B - Nasonia vitripennis
          Length = 655

 Score =  454 bits (1120), Expect = e-126
 Identities = 217/537 (40%), Positives = 318/537 (59%), Gaps = 18/537 (3%)

Query: 20  EEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPL 79
           +E  PERG+W  + +F            N+WRFPYLCY NGGGAF++P+ + L +AG+P+
Sbjct: 75  DEDIPERGSWGSKVEFILSVVGLAIGLGNLWRFPYLCYKNGGGAFMVPYFIALALAGVPM 134

Query: 80  MFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFS 139
             MEL+ GQ   +G + V+ K  P+F+G+GY   ++S    +YY +I+AW +FY  VS  
Sbjct: 135 FLMELALGQMMTIGGLGVF-KIAPIFKGIGYATCVLSCWTNIYYIIILAWALFYFLVSLR 193

Query: 140 SIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTAL 199
           +    +PW+ C+  W++K C +  E  +    + +Y    C     ++SH         L
Sbjct: 194 A---DVPWRTCENSWNSKFCITPLERLKTSCWS-SYGDTVCQTSIGNLSHK--------L 241

Query: 200 RRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTA 259
            + P +E++  + L +S GIE+ G IR  +A  L   W++ + C+ KGV+ +GKVVYFTA
Sbjct: 242 LKDPVKEFWERRTLQISDGIEDVGGIRWELAGTLAIVWIMCYFCIWKGVKWTGKVVYFTA 301

Query: 260 LFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLI 319
           LFPY +LV+L  RG+TLPGA+ G+ +Y TP+ S+L   +VW DA  QIFF+ +   G L+
Sbjct: 302 LFPYCLLVVLLVRGLTLPGAMEGLKYYATPNLSKLGEPEVWIDAVTQIFFSYALGLGALV 361

Query: 320 TLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLA 379
            L SYNKF+NN Y D+LIV   N  TS  +G+VIFSV+GF+AHE    V  V   G GLA
Sbjct: 362 ALGSYNKFNNNVYKDALIVCTVNSCTSMLSGVVIFSVVGFMAHEQQKPVAEVAASGPGLA 421

Query: 380 FIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPN-FRQKKGWVV 438
           F+VYP  V ++P +P+WS LFF MLL +GLDSQF  +E   TA +D +P   R++K   +
Sbjct: 422 FLVYPSAVLQMPGAPMWSCLFFFMLLLIGLDSQFCTVEGFITAAVDEWPRLLRKRKEIFI 481

Query: 439 FIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLI-IAIGECILIAWIYGAEKFCGDI 497
            IV    Y+ GL   T  GMY  QL+D Y+ +  VL+ +   EC+ ++W +G  +F   I
Sbjct: 482 AIVCFLSYIIGLSCITEGGMYVFQLLDSYSVSGFVLLFLMFFECVSVSWAFGVNRFYDGI 541

Query: 498 QRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGW 554
           + MIG     W   W   W +  PA  + +  FN +++ P  Y  Y YP W+  +GW
Sbjct: 542 RDMIGYYPCFW---WKICWTVTVPAICLGVFTFNVVKFSPVKYLDYEYPWWSHVLGW 595


>UniRef50_UPI0000D5722E Cluster: PREDICTED: similar to solute
           carrier family 6 (neurotransmitter transporter,
           glycine), member 5; n=1; Tribolium castaneum|Rep:
           PREDICTED: similar to solute carrier family 6
           (neurotransmitter transporter, glycine), member 5 -
           Tribolium castaneum
          Length = 625

 Score =  452 bits (1114), Expect = e-125
 Identities = 217/554 (39%), Positives = 321/554 (57%), Gaps = 27/554 (4%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           ER  W    +F            NVWRFPYLCY NGGGAFL+ + +M+ + G+PL  +EL
Sbjct: 10  ERSTWNKPLEFVLSCLGYAIGLGNVWRFPYLCYRNGGGAFLVTYIIMIFLMGMPLFLLEL 69

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
             GQY+ LGP   +    PLF GLGY  ++V +++ +YY +IIAWT+FY   SF+    +
Sbjct: 70  IVGQYSGLGPDQAFTNIAPLFTGLGYCTLVVITLITIYYMVIIAWTLFYFFASFTG---E 126

Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQ-------NGTYYLRQCF---------------N 182
           L + +C  +++T  C   ++ D+   Q       N TYY +QC                N
Sbjct: 127 LGFGSCHNDFNTMECVKRQKVDDTLFQIEHSCPPNSTYYNKQCTLVDEICKSYNFEGASN 186

Query: 183 QSYSVSHNITALAKTALRRPPAE-EYFTNQVLGLSSGI-EETGEIRLGMAMCLLAAWVIV 240
           +++  +   T      + R  A  EYF + VL ++    +  G +   + +CLL +W+I 
Sbjct: 187 RTFCYNSTSTVHISRVINRTLATYEYFRDYVLAINDSTWDNFGGLHWQLLLCLLLSWIIG 246

Query: 241 FLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVW 300
           + C+ KGV++SGK VYFTALFPYV+L  L  +GV L GAI GIL YLTP +  L    VW
Sbjct: 247 YFCVIKGVKTSGKAVYFTALFPYVILTALVVQGVILEGAIDGILLYLTPKWEMLLKVDVW 306

Query: 301 GDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFL 360
            +AA Q F++     G L+TL+SYN F+NNC  D+ IV  +NI TS +AG  IFS++GFL
Sbjct: 307 ANAASQTFYSFGTGCGSLVTLASYNNFNNNCLKDTFIVTATNIFTSIYAGFAIFSMLGFL 366

Query: 361 AHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVT 420
           AH++ V V+ V   G GLAF+ YPE + RLP    WS+ FF ML  LGL SQFA +E + 
Sbjct: 367 AHQMGVPVEDVAQDGPGLAFVAYPEAILRLPAPTAWSLAFFFMLFILGLGSQFAGIEAIR 426

Query: 421 TAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGE 480
             ILD++P  R+ + ++  ++ +F ++  +    N G+Y   LM+   A+W++L+I +GE
Sbjct: 427 CLILDKWPKLRKHEIYITLVICLFCFILAIPMCFNGGVYLFTLMEWNTASWAILLIGMGE 486

Query: 481 CILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASY 540
             +++W YG  KF  ++ +M    SK   + W   W +ITP  L+ + +F      PA+Y
Sbjct: 487 VCVVSWCYGCNKFLDNMGQMEMVLSKPARWYWWICWVVITPLTLLGVFIFQMSNMTPATY 546

Query: 541 GHYVYPMWADAVGW 554
             YV+P+WAD++GW
Sbjct: 547 EDYVFPLWADSLGW 560


>UniRef50_Q8MZK8 Cluster: Na+/Cl-dependent neurotransmitter
           transporter-like protein; n=3; Schistosoma|Rep:
           Na+/Cl-dependent neurotransmitter transporter-like
           protein - Schistosoma mansoni (Blood fluke)
          Length = 761

 Score =  452 bits (1113), Expect = e-125
 Identities = 238/582 (40%), Positives = 338/582 (58%), Gaps = 49/582 (8%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           ERG W G+ +F            NVWRFPYLC+ NGGGAFLIP+T+ML + GLPL F+E 
Sbjct: 56  ERGGWNGKLEFMMTCIGYAVGLGNVWRFPYLCFKNGGGAFLIPYTLMLALLGLPLFFLEF 115

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
           +FGQ+A+LGP++V+N   PLF+G+GY MV +S ++ +YY +++A  ++Y  VSF+   + 
Sbjct: 116 AFGQFASLGPISVWN-ISPLFKGIGYAMVFLSWLLNIYYQVVVAHCLYYFGVSFT---HT 171

Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPA 204
           LPW  C   WST  C                        +YS   NIT        + P+
Sbjct: 172 LPWTECNPAWSTPDCIDSNR------------------MNYS---NIT------YPKSPS 204

Query: 205 EEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264
           E+Y+ NQVL LS G EE G     +++CLL+ W++  L + KGVQS GKV YFT++FPY+
Sbjct: 205 EDYYFNQVLKLSPGFEEFGAPGWELSLCLLSCWILCGLAVIKGVQSLGKVSYFTSVFPYI 264

Query: 265 VLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSY 324
           +L IL  RG  LPG+  G+L+YLTPDFS+L + QVW DAA QIFF+L    GGLIT+SSY
Sbjct: 265 MLTILLIRGALLPGSGAGVLYYLTPDFSRLTDPQVWADAATQIFFSLGCCNGGLITVSSY 324

Query: 325 NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYP 384
           NKF NNC  D++IVA+ N ATS +AG VIFS +GF+A++ N ++  V   G GLAFIVYP
Sbjct: 325 NKFKNNCCRDAVIVAIINCATSVYAGFVIFSNLGFMAYQKNTTIVEVASSGPGLAFIVYP 384

Query: 385 EVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNF---RQKKGWVVFIV 441
           E +T +P+S LWS+LFF M+LTLG  SQF+++ET  + I D F        ++  +VF +
Sbjct: 385 EAMTNMPLSSLWSVLFFTMMLTLGFGSQFSILETTLSGIQDEFRRLGVHLTERRKIVFRI 444

Query: 442 AV--FGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQR 499
           +V    +  GL      G Y + + D   + ++ LI+A+ E ++I ++YG ++F  DI+ 
Sbjct: 445 SVCCLNFFMGLPMVCAGGYYLVTIYDSVMSGYAPLIVALSETVVITYVYGLKQFRCDIEL 504

Query: 500 MIGRQSKLWVYLWSAMWRIITPA---ALVFILVFNWIEYKPASYGHYVYPMWADAVGWTX 556
           MI  +     + W   W + TP     L+  ++ N IE K  +Y    +P W   +    
Sbjct: 505 MINERPN---WYWRICWLVFTPTICLLLIISVLTNRIELKEMNYS---FPPWTYVLYHLL 558

Query: 557 XXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWGQA 598
                         + CS    L + E      +P  EWG A
Sbjct: 559 SAGTVLLIVGWFIYKYCSEGGFLLLKE----FLKPVHEWGPA 596


>UniRef50_Q20C86 Cluster: Transporter; n=1; Drosophila virilis|Rep:
           Transporter - Drosophila virilis (Fruit fly)
          Length = 606

 Score =  449 bits (1106), Expect = e-124
 Identities = 231/548 (42%), Positives = 324/548 (59%), Gaps = 38/548 (6%)

Query: 32  RFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAA 91
           + DF            NVWRFPYLCY NGGGAF++P+ + L +AG+P+ FMEL+ GQ   
Sbjct: 13  KLDFILSVVGLAIGLGNVWRFPYLCYKNGGGAFILPYILTLFLAGIPMFFMELALGQMLT 72

Query: 92  LGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCK 151
           +G + V+ K  P+F+G+GY   ++S  + +YY +I+AW +FY    F S+   +PW+ C 
Sbjct: 73  IGGLGVF-KIAPIFKGIGYAAAVMSCWMNVYYIVILAWAVFYF---FMSMRADVPWRTCN 128

Query: 152 AEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSH-NITALAKTALRRPPAEEYFTN 210
             W+T +C +  E       +    +    N+  SV+  NI++   T     P +E++  
Sbjct: 129 NWWNTINCVNQYERKNLHCWDKM--INGTANKVCSVAAANISSTELT----DPVKEFWER 182

Query: 211 QVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILF 270
           + L +SSGI+E G IR  +A  LL  W++ + C+ KGV+ +GKVVYFTALFPYV+L +L 
Sbjct: 183 RALQISSGIDEIGNIRWELAGTLLLVWILCYFCIWKGVKWTGKVVYFTALFPYVLLTVLL 242

Query: 271 FRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNN 330
            RG+TLPGA+ GI FY+ P+FS+L++++VW DA  QIFF+     G L+ L SYNKF+NN
Sbjct: 243 IRGITLPGALEGIKFYIIPNFSKLSHSEVWIDAVTQIFFSYGLGLGTLVALGSYNKFTNN 302

Query: 331 CYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGA-------------- 376
            Y D+LIV   N +TS FAG VIFSVIGF+AHE    V  V   G+              
Sbjct: 303 VYKDALIVCTVNSSTSMFAGFVIFSVIGFMAHEQQRPVAEVAASGSYSAIQKYIYQKYIL 362

Query: 377 --------GLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFP 428
                   GLAF+VYP  V +LP SP+WS LFF MLL +GLDSQF  ME   TAI+D +P
Sbjct: 363 IMQNIKSPGLAFLVYPSAVLQLPGSPMWSCLFFFMLLLIGLDSQFCTMEGFITAIIDEWP 422

Query: 429 N-FRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYA-ANWSVLIIAIGECILIAW 486
              R++K   + IV +  YL GL   T  GMY  Q++D YA + + +L +   EC+ I+W
Sbjct: 423 QLLRKRKEIFIAIVCMLSYLVGLTCITQGGMYIFQILDSYAVSGFCLLWLIFFECVSISW 482

Query: 487 IYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYP 546
            YG ++F   I+ MIG    +W   W   W + TPA  + +  FN +++ P  Y  Y YP
Sbjct: 483 CYGVDRFYDGIKDMIGYYPTVW---WKFCWCVTTPAICLGVFFFNIVQWTPIKYLDYSYP 539

Query: 547 MWADAVGW 554
            WA A GW
Sbjct: 540 WWAHAFGW 547


>UniRef50_UPI0000587A15 Cluster: PREDICTED: similar to amino acid
           transporter B0+ isoform 1; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to amino acid
           transporter B0+ isoform 1 - Strongylocentrotus
           purpuratus
          Length = 773

 Score =  446 bits (1098), Expect = e-123
 Identities = 224/549 (40%), Positives = 328/549 (59%), Gaps = 24/549 (4%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           R  W    D+            NVWRFPYLCY NGGGAFL+P+T+ML+ AGLPL FME++
Sbjct: 53  RETWGSELDYVLSSMGLAIGLGNVWRFPYLCYQNGGGAFLLPYTLMLLFAGLPLYFMEVA 112

Query: 86  FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQL 145
            GQY + G + V+    P+ RGLGYG + +S  V ++YN+++A+ +++   SF+S   +L
Sbjct: 113 LGQYCSSGLIKVWRAVPPM-RGLGYGQLFMSVYVSIFYNVVLAYCLYFFFASFTS---RL 168

Query: 146 PWQNCKAEWSTKHCYS-YEEADE---CEAQNGTYYLRQCFNQSYSVSHNITALAK----- 196
           PW  C   W+T+ C   YEE  E       +         NQ     +N+T + +     
Sbjct: 169 PWIGCSNSWNTRLCSEIYEECIEDGGIVTDDKNCTRLDDLNQDELTYYNVTIIPRNGTYN 228

Query: 197 TALRRP--------PAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGV 248
           T+L R         P++EY+ N+VL  SS + ETG +   + +CLL AWV++FLCL KGV
Sbjct: 229 TSLYRDPFIHVRALPSQEYWKNEVLQESSSMNETGTLVWKLTLCLLLAWVLIFLCLIKGV 288

Query: 249 QSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIF 308
           +S+GKVVYFTA FP+VV+ IL  R  TL G   G+ +Y+ P++ +L +A +W DAAVQIF
Sbjct: 289 KSAGKVVYFTATFPFVVIFILLIRAATLEGHEEGVRYYIYPEWERLKHAVIWRDAAVQIF 348

Query: 309 FALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSV 368
           F+L    GGL+TL+SYNKF +NCY +S+ VAV N  TSF +G +IFS++G++AH+LN SV
Sbjct: 349 FSLGAGGGGLLTLASYNKFHSNCYRNSVFVAVVNCLTSFISGFMIFSIVGYMAHKLNKSV 408

Query: 369 DRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFP 428
                 G GL F+  PE + + P +P WS++FF ML+ L +DSQF  +E + T ++D FP
Sbjct: 409 KDFAHDGFGLVFVACPEALAKFPGAPFWSLMFFFMLILLAVDSQFVGVEVIVTVLIDEFP 468

Query: 429 N-FRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWI 487
           +  R ++  V  I     ++ GL   TN+G YW+ L + YA ++  L+  I     I++I
Sbjct: 469 DILRPRRTLVTGIACFVMFILGLPIVTNAGGYWMALYNNYAVSFVPLVAGILLTCNISYI 528

Query: 488 YGAEKFCGDIQRMIG-RQSKLW-VYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVY 545
           YG  +F  DI+ MIG R    W  + W   W + TP  L  +L+ +W   +  +Y    +
Sbjct: 529 YGFRRFLDDIRVMIGTRIVDHWHFWFWLGNWLVATPLLLGIVLICHWAFDEAPTYNGMAF 588

Query: 546 PMWADAVGW 554
           P WA A+G+
Sbjct: 589 PGWATAIGY 597


>UniRef50_A7S7X6 Cluster: Predicted protein; n=3; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 570

 Score =  444 bits (1094), Expect = e-123
 Identities = 208/549 (37%), Positives = 325/549 (59%), Gaps = 42/549 (7%)

Query: 7   LKGDEEKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLI 66
           LK DE+K    +       R  W  + +F            N WRFPY+C+ NGGGAFLI
Sbjct: 9   LKNDEKKDLVTVES-----RERWDRKIEFLFACIGFAVGYGNFWRFPYMCFKNGGGAFLI 63

Query: 67  PFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLI 126
           P+ + L + G+PL FMELS GQ    GP+  + K CPLF G+G+  +++S IV +YYN+I
Sbjct: 64  PYVLFLCLGGIPLFFMELSLGQLLQEGPIKAWQKICPLFSGIGFASIVISFIVSIYYNVI 123

Query: 127 IAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYS 186
           +AW+++++   ++S F  +PW  C   W+T  CY                        Y+
Sbjct: 124 LAWSLYFL---YNSFFADIPWVGCHHSWNTPDCYV-----------------------YN 157

Query: 187 VSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCK 246
            S N + ++ +        E+    VL ++  IEE G + + + +CLL AW++V+  + +
Sbjct: 158 ASANASGVSSS-------REFLVKNVLEITKSIEEPGGLSVHLTLCLLVAWILVYFSIWR 210

Query: 247 GVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQ 306
           G++++GKVVY TA  PY++LVI F +GVTLPGAI G+L+++TP + +L + +VW DAA Q
Sbjct: 211 GIRTTGKVVYVTATLPYIILVIFFIKGVTLPGAIDGVLYFITPQWDRLQDPKVWIDAASQ 270

Query: 307 IFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNV 366
           I ++L+  +G LI  +SYN   NN + D+L+++V N ATS FAG VIF+++G++AH    
Sbjct: 271 ILYSLTIGFGVLIGFASYNPRKNNVFSDALLISVINCATSVFAGFVIFAIVGYMAHVQEK 330

Query: 367 SVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDR 426
           SV  V  QG GL FIVYP  +++LP   +W+++FF+ML+ LGLDSQF  +E V  A++++
Sbjct: 331 SVPEVASQGPGLVFIVYPAAISQLPFPQIWAVIFFLMLIALGLDSQFGQVEVVAAALIEQ 390

Query: 427 FP-NFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIA 485
           +P    + +  VV ++    +L GL   +  GM+   L D ++   S+L +   E ++I 
Sbjct: 391 WPRQLHKHRELVVLVICFVMFLLGLSCVSKGGMFVFNLFDSFSCGLSLLFVVCFELLVIG 450

Query: 486 WIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVY 545
           WIYGA ++  +I +MIGR    W   W   W+ I+P  ++ I VF+  +YK  +Y +  Y
Sbjct: 451 WIYGARRYADNISQMIGRPVLQW---WVICWKYISPIMVLGIFVFSLAKYKRITYENVPY 507

Query: 546 PMWADAVGW 554
           P WA+ VGW
Sbjct: 508 PAWAEGVGW 516


>UniRef50_UPI000051A316 Cluster: PREDICTED: similar to CG1732-PA,
           isoform A; n=2; Endopterygota|Rep: PREDICTED: similar to
           CG1732-PA, isoform A - Apis mellifera
          Length = 620

 Score =  443 bits (1091), Expect = e-123
 Identities = 216/538 (40%), Positives = 317/538 (58%), Gaps = 17/538 (3%)

Query: 19  SEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLP 78
           + E + ERG W  + DF            NVWRFPYLCY NGGGAFLI + + +V  G+P
Sbjct: 58  NREEDTERGGWDNKLDFLFSCISVSVGLGNVWRFPYLCYKNGGGAFLITYGIAMVFCGIP 117

Query: 79  LMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSF 138
           + F E++ GQY   G + +  + CPL +G+GY  + +   + +YY +IIAWT+FY+  +F
Sbjct: 118 IFFQEVAIGQYLGAGGMTLVGQLCPLLQGVGYATMTIVFFLDVYYCIIIAWTLFYLISTF 177

Query: 139 SSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTA 198
            +I   +PW+ C   W+T+ C+     D  E    T  L    + + + + N+T    T 
Sbjct: 178 VNI-PNVPWKGCGNWWNTEDCF-----DGLEKIEETTDLVNSNSTNSTCNENVTLHHAT- 230

Query: 199 LRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFT 258
               P EEY+  ++LG++ GIE  G I+  +  CL+  W++V+  + +G+  SGK+++F+
Sbjct: 231 ----PVEEYWERRLLGITPGIESIGGIQWELLGCLVIGWLLVYFIIRRGLHQSGKIIWFS 286

Query: 259 ALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGL 318
           ALFPYVVL IL  R VTL G+  G+L+Y+TP + +L +   W D A QIFFA S   G L
Sbjct: 287 ALFPYVVLFILLGRAVTLEGSYNGLLYYVTPRWEELMSPGPWIDGATQIFFAYSIGTGAL 346

Query: 319 ITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGL 378
             L SYNKF +NCY D+LI  V N  T   AG V FS++G +A E    V +VV  G GL
Sbjct: 347 PALGSYNKFHHNCYKDALITCVVNTLTCLLAGCVTFSILGHIALEQGTEVAKVVKSGPGL 406

Query: 379 AFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPN-FRQKKGWV 437
            F+ YPEVV +LP + +W+I+FFVMLL LG+DS+F ++E+  T ++D +P+  R  +   
Sbjct: 407 VFLTYPEVVLKLPGASMWAIIFFVMLLILGIDSEFCIVESFITGVVDNWPDLLRPHRNKF 466

Query: 438 VFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAAN-WSVLIIAIGECILIAWIYGAEKFCGD 496
              +    +L GL   TN G+Y  QLMD Y+A+  S+L +   + I I+WI+GA KFC  
Sbjct: 467 TIAICCLMFLLGLPMVTNGGVYIFQLMDFYSASGMSILWVCFFQTIAISWIFGARKFCDC 526

Query: 497 IQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYG-HYVYPMWADAVG 553
           I +M+G +       W   W +  P  + FI VF  ++YKP  YG +Y YP WA+ +G
Sbjct: 527 IHQMMGIRLN---NFWYVCWVVFAPVIMAFIFVFQCVQYKPLRYGNNYEYPTWAEVIG 581


>UniRef50_Q01959 Cluster: Sodium-dependent dopamine transporter;
           n=131; Coelomata|Rep: Sodium-dependent dopamine
           transporter - Homo sapiens (Human)
          Length = 620

 Score =  442 bits (1090), Expect = e-122
 Identities = 217/554 (39%), Positives = 319/554 (57%), Gaps = 30/554 (5%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           +R  W  + DF            NVWRFPYLCY NGGGAFL+P+ + +VIAG+PL +MEL
Sbjct: 59  DRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMEL 118

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
           + GQ+   G   V+ K CP+ +G+G+ ++++S  V  +YN+IIAW + Y+   FSS   +
Sbjct: 119 ALGQFNREGAAGVW-KICPILKGVGFTVILISLYVGFFYNVIIAWALHYL---FSSFTTE 174

Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPA 204
           LPW +C   W++ +C      D     +G        N ++  +              PA
Sbjct: 175 LPWIHCNNSWNSPNCSDAHPGDSSGDSSG-------LNDTFGTT--------------PA 213

Query: 205 EEYFTNQVLGL--SSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFP 262
            EYF   VL L  S GI++ G  R  +  CL+   V+++  L KGV++SGKVV+ TA  P
Sbjct: 214 AEYFERGVLHLHQSHGIDDLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMP 273

Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322
           YVVL  L  RGVTLPGAI GI  YL+ DF +L  A VW DAA Q+ F+L   +G LI  S
Sbjct: 274 YVVLTALLLRGVTLPGAIDGIRAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFS 333

Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIV 382
           SYNKF+NNCY D+++    N  TSF +G V+FS +G++A + +V +  V   G GL FI+
Sbjct: 334 SYNKFTNNCYRDAIVTTSINSLTSFSSGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFII 393

Query: 383 YPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVA 442
           YPE +  LP+S  W+++FF+MLLTLG+DS    ME+V T ++D F    + +      + 
Sbjct: 394 YPEAIATLPLSSAWAVVFFIMLLTLGIDSAMGGMESVITGLIDEFQLLHRHRELFTLFIV 453

Query: 443 VFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIG 502
           +  +L  L   TN G+Y   L+D +AA  S+L   + E I +AW YG  +F  DIQ+M G
Sbjct: 454 LATFLLSLFCVTNGGIYVFTLLDHFAAGTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTG 513

Query: 503 RQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGWTXXXXXXX 562
           ++  L+   W   W++++P  L+F++V + + ++P  YG Y++P WA+A+GW        
Sbjct: 514 QRPSLY---WRLCWKLVSPCFLLFVVVVSIVTFRPPHYGAYIFPDWANALGWVIATSSMA 570

Query: 563 XXXXXXXDQICSGP 576
                   + CS P
Sbjct: 571 MVPIYAAYKFCSLP 584


>UniRef50_Q3I1M7 Cluster: Serotonin transporter; n=5;
           Schistosoma|Rep: Serotonin transporter - Schistosoma
           mansoni (Blood fluke)
          Length = 735

 Score =  442 bits (1089), Expect = e-122
 Identities = 219/539 (40%), Positives = 314/539 (58%), Gaps = 19/539 (3%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           +R  W  + DF            N+WRFP++CY NGGGAFLIP+ VM +  GLPL ++EL
Sbjct: 142 KREIWDSKIDFLLAVIGFAVDLGNIWRFPFICYRNGGGAFLIPYLVMYIFGGLPLFYLEL 201

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
           + GQY   G + V+ + CPLF G+G+G+ I++S    YYN IIAW +FYM  +       
Sbjct: 202 ALGQYQRSGCLTVWKRICPLFSGVGFGICIIASYTAWYYNTIIAWALFYMIDAMKP---H 258

Query: 145 LPWQNCKAEWSTKHCYS-YEEADECEAQNGT--YYLRQCFNQSYSVSHNITALAKTALRR 201
           +PW  C   W+T  C + YE        N +  Y L +  N S + S  I    K     
Sbjct: 259 IPWDGCNNWWNTNSCVTVYERLINHSILNASHKYELNELVNLSIA-SLKINGSGKVF--- 314

Query: 202 PPAEEYFTNQVLGL--SSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTA 259
              EEYF  +VL +  + G    G IR  +++CL+A + IV+  L KGV+SSGK V+ TA
Sbjct: 315 SSTEEYFYRRVLQIQYAEGYNNVGPIRWEISLCLMAVFTIVYFSLWKGVKSSGKAVWVTA 374

Query: 260 LFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLI 319
             PYV+L IL  RG+TL G++TGI +YLTP+FS L +  VW DAA QIFF+L P +G L+
Sbjct: 375 TLPYVILSILLIRGLTLEGSLTGIKYYLTPNFSSLLSISVWSDAASQIFFSLGPGFGVLL 434

Query: 320 TLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLA 379
            LSSYNKF NNCY D++I +  N ATSF +G V+FSV+G++   +  +++ V ++G GL 
Sbjct: 435 ALSSYNKFHNNCYRDAMITSFINCATSFVSGFVVFSVLGYMCFRMGKTMEDVANEGPGLV 494

Query: 380 FIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVF 439
           FI YPE +  L  S  W+I+F +ML+TLGLDS F  +E + TAI+D  P    ++   V 
Sbjct: 495 FIAYPEAIATLAGSTFWAIIFMLMLITLGLDSTFGGLEAIITAIMDSVPALSGRREVFVL 554

Query: 440 IVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQR 499
            V ++ ++G L  TT  G   L ++D++ A  S+L I   EC+ + W YG ++FC D+Q 
Sbjct: 555 AVVIYCFIGALPSTTCGGYLVLTMLDRHGAPISILFIVFCECVALCWFYGTKRFCNDVQM 614

Query: 500 MIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEY--KPASYGHYVY--PMWADAVGW 554
           M+G +  ++   W   W  I+P  L+ I + N + Y  +P S    VY    W   + W
Sbjct: 615 MLGFKPGIF---WQICWAYISPIFLLGIFIANIVSYETQPVSVLGVVYEPTTWVIVLSW 670


>UniRef50_Q2ABP4 Cluster: Taurine transporter; n=2;
           Pteriomorphia|Rep: Taurine transporter - Crassostrea
           gigas (Pacific oyster) (Crassostrea angulata)
          Length = 671

 Score =  439 bits (1081), Expect = e-121
 Identities = 220/538 (40%), Positives = 323/538 (60%), Gaps = 22/538 (4%)

Query: 29  WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQ 88
           W  + DF            NVWRFP+LCY NGGGAFLIP+   +++ G+P+ F+E+S GQ
Sbjct: 47  WANKLDFLLACIGFSVGLGNVWRFPFLCYRNGGGAFLIPYFTAVLLGGIPVFFLEVSLGQ 106

Query: 89  YAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQ 148
           + + G +  + K  PLF+G+GY   I+  ++   YN+I+ WT +Y+  SF+++   LPW 
Sbjct: 107 FMSEGGIGTW-KITPLFQGIGYACTIIVFLLNCEYNIILTWTFYYLFSSFNTV---LPWS 162

Query: 149 NCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRR-----PP 203
               EW+++ C     + +  A   + Y +   +    ++  +T +A T          P
Sbjct: 163 QGDNEWNSELC---RNSSKMAASLMSNYSKMASSVVSKLNDTMTTVAYTVATENTTKCDP 219

Query: 204 AEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPY 263
             E++ ++VL LSSG++  G ++  +A+CLL AW++V+ C+ KG++SSGKV+YFTA  PY
Sbjct: 220 VTEFWESKVLQLSSGVDHAGTVKWDLALCLLLAWIVVYGCIWKGIKSSGKVMYFTATSPY 279

Query: 264 VVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSS 323
           ++++IL  RGVTL GA  G+ FYL PD+S+L  AQVW DA  QIFF+ S + G L  L S
Sbjct: 280 ILMLILLIRGVTLDGAAEGLKFYLLPDWSKLQEAQVWVDAGTQIFFSYSISLGTLTALGS 339

Query: 324 YNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVY 383
           YNKF +N Y D++I A  N  TS  AGLVIFSV+GF+A +  VSV  V + G GLAFI Y
Sbjct: 340 YNKFRHNSYRDAMIFAGVNSFTSILAGLVIFSVLGFMAKQQGVSVADVAESGPGLAFIAY 399

Query: 384 PEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNF-RQKKGWVVF--I 440
           P  V ++P++PLWS+LFFVM++ LGLDSQF  +E   TA +D +P++ R  K   +F  I
Sbjct: 400 PTAVAQMPVAPLWSVLFFVMIILLGLDSQFVGVEGFITACVDMYPHYLRIGKRREIFTGI 459

Query: 441 VAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRM 500
           V    +L GL   T  GMY  QL D Y+A+  VL++A  ECI++A+IYG  ++  +++ M
Sbjct: 460 VCFICFLIGLSMVTEGGMYVFQLFDYYSASRIVLVVAFFECIVVAYIYGINRYYDNLEMM 519

Query: 501 IGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYG----HYVYPMWADAVGW 554
            G +      +    W  +TP   + I +   I Y   +Y      Y YP WA  VGW
Sbjct: 520 FGFRI---APVMKICWMFVTPLFSLTIFIMGAISYSELTYKRKTYEYTYPSWAIGVGW 574


>UniRef50_Q7Q4L1 Cluster: Transporter; n=1; Anopheles gambiae str.
           PEST|Rep: Transporter - Anopheles gambiae str. PEST
          Length = 576

 Score =  436 bits (1075), Expect = e-121
 Identities = 215/574 (37%), Positives = 324/574 (56%), Gaps = 18/574 (3%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           +RG+W  + +F            NVWRFPYLCY NGGGAFL+P+ +MLV+ G+PL F+E 
Sbjct: 13  KRGHWASKTEFILSCIGYAIGLGNVWRFPYLCYRNGGGAFLVPYLLMLVLCGIPLFFLET 72

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
             GQ++  G + V+ K  PL +G G  +V+++ I   YY  II++ + ++   + S+  Q
Sbjct: 73  CLGQFSGTGCITVF-KIVPLLKGAGIAIVVLNLICNAYYIAIISYPLLFL---WRSLQAQ 128

Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPA 204
           LPW++C   W+T  C         E       +       Y +    + L    L     
Sbjct: 129 LPWESCGNAWNTPRCLELRGDQHVELFLNNSAM--AIGDRYLLEVVESLLEHQGLFLVVV 186

Query: 205 EEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264
               +N++L +S GIE+ G I   + +C + AW+++F C+ KGVQS GKVVY TA FP+ 
Sbjct: 187 ---CSNEILHISEGIEQMGGIVWPLLLCDVIAWIVIFGCIAKGVQSVGKVVYCTATFPFA 243

Query: 265 VLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSY 324
           +L +L  RG+TLPGA+ GI FY+ P +SQL N +VW DAA+QIF++L P WGG++ ++SY
Sbjct: 244 ILAVLLVRGITLPGALEGIKFYIMPQWSQLLNLRVWADAAIQIFYSLGPGWGGILNMASY 303

Query: 325 NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYP 384
           N+F NN  +DS+++ + N  TS  AG V+FSV+G+ +H+  + V      G GLAFI YP
Sbjct: 304 NQFKNNTKLDSIVIPIVNCGTSILAGFVVFSVLGYFSHQTGLPVASAATGGPGLAFITYP 363

Query: 385 EVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVF 444
           E ++ LP+SPLW+ LFF ML  LG+DS F  +E + ++++D  P  R  K   + + A  
Sbjct: 364 EAISMLPLSPLWACLFFSMLFFLGVDSMFVQIEAIVSSVMDVLPRLRPMK---LQVTAGT 420

Query: 445 GYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQ 504
            +L  L+     GMY +QL+D Y+ + SV+++ I E I + WIYG E+F  D++ MI R+
Sbjct: 421 CFLLFLLSIACGGMYLVQLLDWYSGSISVILVCIVEVITVGWIYGCEQFVRDVEFMIDRK 480

Query: 505 SKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGWTXXXXXXXXX 564
            + +   W   W+ ITP  L FI     +     SY  + YP WA  VGW          
Sbjct: 481 VERF---WIVSWKYITPIVLTFIFTTTIVYNTEVSYNGFSYPRWAIGVGWASCLVSILCI 537

Query: 565 XXXXXDQICSGPDDLTIMEKARVLARPTEEWGQA 598
                 ++      LT   K ++ A   ++WG A
Sbjct: 538 PVFASYKLLHTKGSLTKRFKTQLKA---QDWGPA 568


>UniRef50_P31645 Cluster: Sodium-dependent serotonin transporter;
           n=58; Coelomata|Rep: Sodium-dependent serotonin
           transporter - Homo sapiens (Human)
          Length = 630

 Score =  434 bits (1069), Expect = e-120
 Identities = 215/541 (39%), Positives = 326/541 (60%), Gaps = 36/541 (6%)

Query: 18  LSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGL 77
           ++E  + ER  W  + DF            NVWRFPY+CY NGGGAFL+P+T+M +  G+
Sbjct: 71  VAELHQGERETWGKKVDFLLSVIGYAVDLGNVWRFPYICYQNGGGAFLLPYTIMAIFGGI 130

Query: 78  PLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVS 137
           PL +MEL+ GQY   G ++++ K CP+F+G+GY + I++  +  YYN I+AW ++Y+  S
Sbjct: 131 PLFYMELALGQYHRNGCISIWRKICPIFKGIGYAICIIAFYIASYYNTIMAWALYYLISS 190

Query: 138 FSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKT 197
           F+    QLPW +CK  W+T +C +Y   D     N T+ L       +S S         
Sbjct: 191 FTD---QLPWTSCKNSWNTGNCTNYFSED-----NITWTL-------HSTS--------- 226

Query: 198 ALRRPPAEEYFTNQVLGL--SSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVV 255
                PAEE++T  VL +  S G+++ G I   +A+C++  + +++  + KGV++SGKVV
Sbjct: 227 -----PAEEFYTRHVLQIHRSKGLQDLGGISWQLALCIMLIFTVIYFSIWKGVKTSGKVV 281

Query: 256 YFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAW 315
           + TA FPY++L +L  RG TLPGA  G+LFYL P++ +L    VW DAA QIFF+L P +
Sbjct: 282 WVTATFPYIILSVLLVRGATLPGAWRGVLFYLKPNWQKLLETGVWIDAAAQIFFSLGPGF 341

Query: 316 GGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVV-DQ 374
           G L+  +SYNKF+NNCY D+L+ +V N  TSF +G VIF+V+G++A   N  V  V  D 
Sbjct: 342 GVLLAFASYNKFNNNCYQDALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNEDVSEVAKDA 401

Query: 375 GAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPN-FRQK 433
           G  L FI Y E +  +P S  ++I+FF+ML+TLGLDS FA +E V TA+LD FP+ + ++
Sbjct: 402 GPSLLFITYAEAIANMPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHVWAKR 461

Query: 434 KGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKF 493
           +   V  V +  + G L+  T  G Y ++L+++YA   +VL +A+ E + ++W YG  +F
Sbjct: 462 RERFVLAVVITCFFGSLVTLTFGGAYVVKLLEEYATGPAVLTVALIEAVAVSWFYGITQF 521

Query: 494 CGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVG 553
           C D++ M+G  S  W   W   W  I+P  L+FI+    +         Y YP W+  +G
Sbjct: 522 CRDVKEMLG-FSPGW--FWRICWVAISPLFLLFIICSFLMSPPQLRLFQYNYPYWSIILG 578

Query: 554 W 554
           +
Sbjct: 579 Y 579


>UniRef50_UPI0000E4A7A9 Cluster: PREDICTED: similar to choline
           transporter; n=8; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to choline transporter -
           Strongylocentrotus purpuratus
          Length = 855

 Score =  426 bits (1049), Expect = e-117
 Identities = 218/543 (40%), Positives = 319/543 (58%), Gaps = 20/543 (3%)

Query: 23  EPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFM 82
           +  RG WT + DF            NVWRFPYLCY NGGGAFLIP+ + L++ G+P + +
Sbjct: 220 QKSRGTWTSQLDFLLALIGASVGLGNVWRFPYLCYKNGGGAFLIPYFICLILGGIPQLIL 279

Query: 83  ELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIF 142
           E+  GQ+     V  ++  CP+F+GLG   + +   +  YY +I+AW ++YM +SF+S  
Sbjct: 280 EIGLGQWTNQAAVTAWD-ICPIFKGLGGAGMFIQFFLDTYYIVIMAWALYYMFMSFTS-- 336

Query: 143 YQLPWQNCKAEWSTKHCYSY--EEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALR 200
            +LP+ +C  EW+T  C +      D  E           ++ + + S N+T        
Sbjct: 337 -KLPYSHCDNEWNTPCCLATGASSLDANETTTAMTSTEMSYDPTGTPSWNLTDPCNGTTI 395

Query: 201 RPPAEEYFTNQVLG--LSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFT 258
               E ++  ++L   LS GIE+ G I   + +C+  AW + +LC+CKGV++SGKVVYFT
Sbjct: 396 SSTVE-FWDRKILQIHLSDGIEQLGGINWQLLLCMFFAWFLCYLCICKGVKTSGKVVYFT 454

Query: 259 ALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGL 318
           A FPY+++ IL  R VTL GA+ GI++YL PD S+L ++QVW DAA QIFF+ S   G L
Sbjct: 455 APFPYILMTILLIRAVTLEGAMDGIVYYLKPDISRLNDSQVWMDAATQIFFSYSLGQGVL 514

Query: 319 ITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGL 378
           I L SYNK  +N   D+LI +V+N  TS ++G VIF+V+GF+A +  V V  V   G GL
Sbjct: 515 IALGSYNKHKHNFIRDALIFSVANTGTSLYSGFVIFAVLGFMAGQQGVDVSVVAKSGPGL 574

Query: 379 AFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK---KG 435
           AFI YPE +T++P S LW++LFF+ LL LG+DSQF  +E     I+D FPN   K   + 
Sbjct: 575 AFIAYPEAITQMPASTLWAVLFFLCLLVLGIDSQFVGVEGFVATIVDLFPNTLLKGHRRE 634

Query: 436 WVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLI-IAIGECILIAWIYGAEKFC 494
                V +F  + G+   T  GMY  QL D YAA+  VL+ +++ E I I W YG  +F 
Sbjct: 635 IFCIFVCLFFCIAGIPMCTYGGMYIFQLFDYYAASGFVLLWVSMFESITIGWAYGGFRFM 694

Query: 495 GDIQRMIGRQSKLWV--YLWSAMWRIITPAALVFILVFNWIEYKPASYGH-YVYPMWADA 551
            ++  M G +   W+  Y+ +A W  ++P     I +F+ ++YKP +Y + YVYP W   
Sbjct: 695 KNVTEMSGVK---WISPYMITA-WIFLSPLFTFAIFIFSLVKYKPLTYNNTYVYPWWGYM 750

Query: 552 VGW 554
           +GW
Sbjct: 751 IGW 753


>UniRef50_Q5J2D5 Cluster: GABA transporter protein; n=2;
           Caenorhabditis|Rep: GABA transporter protein -
           Caenorhabditis elegans
          Length = 610

 Score =  426 bits (1049), Expect = e-117
 Identities = 229/589 (38%), Positives = 324/589 (55%), Gaps = 27/589 (4%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           ER  W+   DF            NVWRFPYLCY NGGGAFLIP+ + LV  G PL  +E 
Sbjct: 9   EREQWSSWADFIMSCIGYAIGLGNVWRFPYLCYQNGGGAFLIPYCISLVFCGAPLFILET 68

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
           S+GQ  ++G + ++ K CP+F+G+G    +++  + +YY ++++W   Y+  SF+     
Sbjct: 69  SWGQLMSVGGLGMF-KICPIFKGVGIAAAVMAFWLNIYYIVVLSWAATYLYNSFT--MSD 125

Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNG----------TYYLRQCFNQSYSVSH--NIT 192
           +PW+NC   W+T +C S      C++             T+     + + + V    N T
Sbjct: 126 VPWKNCDHAWNTPNCRSEYVKIPCDSNRTIAEFFNVKVLTHDHIHEYKKQFFVGEKMNWT 185

Query: 193 ALAKTALRR-PPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSS 251
             +   L    P +E++ ++VLG+SSG+E  G IR  +A+ LL  W+I +LC+ KGV+ +
Sbjct: 186 VCSAADLSVVSPVKEFWNHRVLGISSGLENPGGIRWDLALFLLLVWIICYLCIFKGVKWT 245

Query: 252 GKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFAL 311
           GKVVY TA FPY++L  L  RG+TL GA  G+ FYL PDFS+L  ++VW DA  Q+FF+ 
Sbjct: 246 GKVVYITASFPYMMLFCLLIRGLTLEGAGVGLEFYLKPDFSKLLESKVWVDAVTQVFFSY 305

Query: 312 SPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRV 371
               G L+ L SYNKF+NN Y  +L V   N  TS FAG VIFS IGF+A +   SV  V
Sbjct: 306 GLGLGALVALGSYNKFNNNVYKQALTVCFVNSGTSVFAGFVIFSFIGFMATQQEKSVAEV 365

Query: 372 VDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFR 431
              G GL F+ YP  + +LP +  WS LFF+M+L LG+DSQF  ME   TAI+D FP  R
Sbjct: 366 AQAGPGLLFLAYPSGILQLPYTQFWSCLFFLMVLFLGVDSQFCTMEGFFTAIIDEFPQIR 425

Query: 432 QKK-GWVVF--IVAVFGYLGGLIFTTNSGMYWLQLMDKYAAN-WSVLIIAIGECILIAWI 487
           +KK G  +F  ++ V  YL GL   T  G Y  QL D YAA+ W++L +   ECI I+W 
Sbjct: 426 RKKYGREIFVGVICVISYLIGLTTVTEGGFYVFQLFDFYAASGWALLWLLFFECIAISWS 485

Query: 488 YGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYG--HYVY 545
            G +++   ++ MIG     W   W   W   TP+    +L+F  I+Y+P      +Y Y
Sbjct: 486 LGIDRWYEHMKSMIGYYPSAW---WKFCWVFATPSVCFGVLLFGLIKYQPLRIDAYNYDY 542

Query: 546 PMWADAVGWTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEE 594
           P+W    GW                     P   T+ EK ++L RP  E
Sbjct: 543 PVWGHIFGWFLSLSSMLCIPGYAIWIWFKTPG--TVQEKIKLLCRPDIE 589


>UniRef50_Q03614 Cluster: Sodium-dependent dopamine transporter;
           n=6; Bilateria|Rep: Sodium-dependent dopamine
           transporter - Caenorhabditis elegans
          Length = 615

 Score =  425 bits (1047), Expect = e-117
 Identities = 211/546 (38%), Positives = 316/546 (57%), Gaps = 35/546 (6%)

Query: 19  SEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLP 78
           +E  +P R  W+G+ DF            N+WRFPYLC+ NGGG FLIP+++M+++ G+P
Sbjct: 33  TEPKDPAREQWSGKLDFLLSVVGFAVDLGNIWRFPYLCFKNGGGVFLIPYSIMVLLTGVP 92

Query: 79  LMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSF 138
           L +MEL  GQY   G +  + + CPLF+G+GY +++ +  V  +YN+I+AW + Y+  SF
Sbjct: 93  LFYMELCLGQYYRKGAITTWGRICPLFKGIGYCVILTAFYVDFFYNVILAWGLHYLYTSF 152

Query: 139 SSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTA 198
           S   + LPW +C   +++  CY    +++     GT   R   NQS S +  I+A     
Sbjct: 153 S---FNLPWASCNNSYNSPACYEPHWSED-----GTAMCRSA-NQSVS-AEKISA----- 197

Query: 199 LRRPPAEEYFTNQVLGLSSG----------IEETGEIRLGMAMCLLAAWVIVFLCLCKGV 248
                AEEYF    LGL             + + G +R  +A+ L   ++I +  + KG+
Sbjct: 198 -----AEEYFYKGFLGLHEANAPNSHVIRSVTDLGNVRWDIALSLFVVYLICYFSMWKGI 252

Query: 249 QSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIF 308
            +SGKVV+FTALFPYVVL ILF RGVTLPG   GI +YL P+F  L    VW DAA Q+F
Sbjct: 253 HTSGKVVWFTALFPYVVLGILFIRGVTLPGWQNGIEYYLRPNFEMLKRPSVWQDAATQVF 312

Query: 309 FALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSV 368
           F+L P +G L+  SSYN F NN Y+D+L  +  N ATSF +G VIFSV+G+++ +    +
Sbjct: 313 FSLGPGFGVLMAYSSYNDFHNNVYVDALFTSFINCATSFLSGFVIFSVLGYMSCKSGKPI 372

Query: 369 DRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFP 428
           + V  +G GL F+VYPE ++ +P +P WS+LFF+ML+TLGLDS F   E + T + D FP
Sbjct: 373 EAVAQEGPGLVFVVYPEALSTMPYAPFWSVLFFLMLMTLGLDSSFGGSEAIITGLSDEFP 432

Query: 429 NFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIY 488
             ++ +   V  +  F  + G+   T  G+  ++ +  Y   W +LI    E ++IA+IY
Sbjct: 433 ILKKNREVFVGCLFAFYMVIGIAMCTEGGILIMEWLIIYGTTWGLLIAVFCEAMVIAYIY 492

Query: 489 GAEKFCGDIQRMIG-RQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPM 547
           G  +F  D++ M+G R    W + WS       P  L+ ++  N+I Y+  +Y  Y YP 
Sbjct: 493 GLRQFVHDVKEMMGFRPGNYWKFCWSC----AAPFILLSMITSNFINYQALTYQDYTYPT 548

Query: 548 WADAVG 553
            A+ +G
Sbjct: 549 AANVIG 554


>UniRef50_P51905 Cluster: Sodium-dependent serotonin transporter;
           n=7; Protostomia|Rep: Sodium-dependent serotonin
           transporter - Drosophila melanogaster (Fruit fly)
          Length = 622

 Score =  424 bits (1045), Expect = e-117
 Identities = 210/535 (39%), Positives = 317/535 (59%), Gaps = 38/535 (7%)

Query: 23  EPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFM 82
           E  R  W  + +F            NVWRFPY+CY NGGGAFL+P+ + L+  GLPL +M
Sbjct: 71  ERTRETWGQKAEFLLAVIGFAVDLGNVWRFPYICYQNGGGAFLVPYCLFLIFGGLPLFYM 130

Query: 83  ELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIF 142
           EL+ GQ+   G ++++ + CP  +G+GY + ++   + +YYN II W ++Y+  SF+S  
Sbjct: 131 ELALGQFHRCGCLSIWKRICPALKGVGYAICLIDIYMGMYYNTIIGWAVYYLFASFTS-- 188

Query: 143 YQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRP 202
            +LPW +C   W+T++C                            S N T LA +     
Sbjct: 189 -KLPWTSCDNPWNTENCMQV------------------------TSENFTELATS----- 218

Query: 203 PAEEYFTNQVLGL--SSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTAL 260
           PA+E+F  +VL     +G++  G ++  +A+C+   +V+V+  L KGV+S+GKVV+ TAL
Sbjct: 219 PAKEFFERKVLESYKGNGLDFMGPVKPTLALCVFGVFVLVYFSLWKGVRSAGKVVWVTAL 278

Query: 261 FPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLIT 320
            PYVVL+IL  RGV+LPGA  GI +YLTP++ +L N++VW DAA QIFF+L P +G L+ 
Sbjct: 279 APYVVLIILLVRGVSLPGADEGIKYYLTPEWHKLKNSKVWIDAASQIFFSLGPGFGTLLA 338

Query: 321 LSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAF 380
           LSSYNKF+NNCY D+LI +  N  TSF AG VIFSV+G++A+    S+D+V  +G GL F
Sbjct: 339 LSSYNKFNNNCYRDALITSSINCLTSFLAGFVIFSVLGYMAYVQKTSIDKVGLEGPGLVF 398

Query: 381 IVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPN-FRQKKGWVVF 439
           IVYPE +  +  S  WSI+FF+ML+TLGLDS F  +E + TA+ D +P    +++   V 
Sbjct: 399 IVYPEAIATMSGSVFWSIIFFLMLITLGLDSTFGGLEAMITALCDEYPRVIGRRRELFVL 458

Query: 440 IVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQR 499
           ++  F +L  L   T  G+  +  ++ Y    ++L +   E   + W YG ++F  D+++
Sbjct: 459 LLLAFIFLCALPTMTYGGVVLVNFLNVYGPGLAILFVVFVEAAGVFWFYGVDRFSSDVEQ 518

Query: 500 MIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGW 554
           M+G +  L+   W   W  I+P  L+ I +F+ + YK      Y YP W+  VGW
Sbjct: 519 MLGSKPGLF---WRICWTYISPVFLLTIFIFSIMGYKEMLGEEYYYPDWSYQVGW 570


>UniRef50_UPI0000E47635 Cluster: PREDICTED: similar to high-affinity
           serotonin transporter; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to high-affinity
           serotonin transporter - Strongylocentrotus purpuratus
          Length = 641

 Score =  418 bits (1029), Expect = e-115
 Identities = 206/534 (38%), Positives = 316/534 (59%), Gaps = 39/534 (7%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           ER  W  + DF            N+WRFPY+CY NGGGAFL+P+ +M +  G+P ++ME+
Sbjct: 90  ERAVWGKKADFLLSVIGFTVDLGNIWRFPYICYKNGGGAFLVPYALMAIFGGVPFLYMEM 149

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
           + GQY   G + V+ + CP+  G+GY + I++  V  +Y+ I AW+++Y+  SF++    
Sbjct: 150 ALGQYQRTGCITVWRRICPIMGGIGYAICIINCYVGFFYSTITAWSVYYLIASFATT--- 206

Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPA 204
           LPW +C  +W+                  T +    F +++S + ++T          PA
Sbjct: 207 LPWTSCDNDWN------------------TEFCASPFAENFS-NTSVT----------PA 237

Query: 205 EEYFTNQVLG--LSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFP 262
            E+F  +V+G  LS+GI + G ++  +A+CLL  +VIV+  + KG+++SGKVV+ TA  P
Sbjct: 238 TEFFERKVIGSHLSTGIGDLGGLKWELALCLLLLFVIVYFSIWKGIKASGKVVWVTATLP 297

Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322
           Y  L++L  RGVTL GA +GI++YL P +  L NA VW DAAVQ+FF+L P +G ++  S
Sbjct: 298 YFCLIVLLIRGVTLEGASSGIIYYLKPKWHLLRNAGVWVDAAVQVFFSLGPGFGVILAFS 357

Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIV 382
           SYNK  NNC+ D+LI +  N  TSF AG  IFSV+GF++ +    ++ V   G GL +I 
Sbjct: 358 SYNKLHNNCFKDALITSGINCFTSFLAGFAIFSVLGFMSVQQGRDIEEVTPDGPGLIYIA 417

Query: 383 YPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWV-VFIV 441
            PE +++LP S  W+++FFVM+++LGLDS F  +E++ TA  DR P    K   + V  V
Sbjct: 418 IPEAISQLPGSTWWAVIFFVMIISLGLDSTFGGLESIITAWCDRNPKTIGKHREIFVACV 477

Query: 442 AVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMI 501
             F +LG L   T  G Y  QL++ Y A+ ++L++ + E I I W YG + F  DI+ MI
Sbjct: 478 VCFIFLGSLTTVTYGGQYVFQLLESYGASTTLLLVVVLEAISITWFYGLQNFTSDIRTMI 537

Query: 502 GRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKP-ASYGHYVYPMWADAVGW 554
           GR   ++   W   W I++PA L+F++VF    ++P   +    YP W+  VGW
Sbjct: 538 GRTPSVY---WQLCWSILSPAMLLFVVVFGLFMHRPMVGFQGEPYPQWSIGVGW 588


>UniRef50_UPI00015B4B04 Cluster: PREDICTED: similar to
           neurotransmitter transporter; n=1; Nasonia
           vitripennis|Rep: PREDICTED: similar to neurotransmitter
           transporter - Nasonia vitripennis
          Length = 992

 Score =  417 bits (1028), Expect = e-115
 Identities = 206/557 (36%), Positives = 324/557 (58%), Gaps = 39/557 (7%)

Query: 6   CLKGDEEKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFL 65
           C   D+  ++ P  E  +P R +W  +  F            NVWRFPYLCY +GGG FL
Sbjct: 382 CTSFDDGDAEDP-GEYRQPRRPHWENKVQFVLACIGYSVGLGNVWRFPYLCYKSGGGVFL 440

Query: 66  IPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNL 125
           IP+ ++L++ G+PL++MELS GQ+   GP+    + CPLF+G G   V++S ++  Y+N+
Sbjct: 441 IPYFLILIVCGVPLLYMELSIGQFTRRGPIGALGQICPLFKGAGLSSVVISFLMSTYHNV 500

Query: 126 IIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSY 185
           IIA+ I+Y       I    PW  C+ +W++  C+S   AD     N T           
Sbjct: 501 IIAYAIYYFFTGCKPI---QPWSRCRNKWNSPDCWS---ADVMTNNNNT----------- 543

Query: 186 SVSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLC 245
                     +    + P+ E+F N+VL +SSGIEE G +R  +A CL++AWVIV+  + 
Sbjct: 544 ----------RPKHPKIPSAEFFDNKVLQISSGIEEPGMLRWELAACLISAWVIVYFSIW 593

Query: 246 KGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAV 305
           K ++SS +V Y TA  P++++ I   R +TL GA  G+ F+  PD+  L +A+VW +AA 
Sbjct: 594 KSIKSSARVRYLTATLPFLLIFIFLTRSLTLEGADKGLQFFFRPDWQLLKDAKVWVNAAA 653

Query: 306 QIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELN 365
           QIF ++  A+G +I  +SYNKF NN  ID++ V++ N  +    G+  F+ IG +A E N
Sbjct: 654 QIFNSVGIAFGSMICFASYNKFHNNILIDTVAVSLINACSCLLVGIFAFATIGNIAVEQN 713

Query: 366 VSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILD 425
           ++V  V+  G GL F+VYP+ + ++P   +W++LFF ML+ L L+SQFA++E V T+I D
Sbjct: 714 MTVPEVLSDGPGLVFVVYPQALAKMPWPQMWAMLFFFMLVCLSLNSQFAIVEVVVTSIQD 773

Query: 426 RFPNFRQK----KGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGEC 481
            FP + +K       +V +V +  +L GL   T  G+Y+ QL+D YAA+ S++ +A  E 
Sbjct: 774 GFPKWVKKHLLCHEMLVLLVCIVSFLFGLPNITQGGIYFFQLIDHYAASISIMFLAFFEV 833

Query: 482 ILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASY- 540
           I I+W YG  + C +++ M GR   ++   +   W + +P  ++ + VF+ I+Y+P  Y 
Sbjct: 834 IAISWFYGVRRLCSNVKEMTGRVPSIY---FRFCWLVASPLLIMAVWVFSLIDYEPPHYT 890

Query: 541 ---GHYVYPMWADAVGW 554
              G Y YP WA+A+GW
Sbjct: 891 RSDGKYTYPWWAEAIGW 907


>UniRef50_Q9VLY6 Cluster: Transporter; n=7; Endopterygota|Rep:
           Transporter - Drosophila melanogaster (Fruit fly)
          Length = 590

 Score =  416 bits (1025), Expect = e-115
 Identities = 200/535 (37%), Positives = 321/535 (60%), Gaps = 35/535 (6%)

Query: 21  EIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLM 80
           E +  RG W  + +F            NVWRFPYLCY +GG AFLIP+ +M+++AG+PL 
Sbjct: 19  ERDENRGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFLIPYLLMVILAGIPLF 78

Query: 81  FMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSS 140
           +ME+  GQ+++ G   ++ +  PL +G G   V+V++  + YY++II++ I    + F  
Sbjct: 79  YMEILIGQFSSTGCTGMF-RMTPLLKGTGIAQVVVNAYCVCYYSVIISYPI---RMIFYC 134

Query: 141 IFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALR 200
            F ++PW++C   W+T  C +   A +   QN +                   + KT+  
Sbjct: 135 FFKKVPWEDCSNSWNTDDCVT---ASDMGKQNSS------------------DVFKTS-- 171

Query: 201 RPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTAL 260
              A+E+F  +VL +S+ I + G +       L+  W+I++ CL +G++S GKVVYFT  
Sbjct: 172 ---ADEFFHLEVLRISTDISDLGGMVWEQLTALIITWIIIYFCLMRGIKSVGKVVYFTVP 228

Query: 261 FPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLIT 320
           FPY++L IL  RG TLPGA  GI FYL P++ +L + +VW DAAVQ+FF + P WGG++ 
Sbjct: 229 FPYLLLFILLIRGATLPGAWKGIKFYLYPEWHRLLDLKVWADAAVQMFFGIGPGWGGIVN 288

Query: 321 LSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAF 380
           ++S++ F NN   DS+++   N+ TS  AG V+FSV+GFL+ +  + V+ V   GAGLAF
Sbjct: 289 MASFSSFRNNAKCDSVLIVSINVFTSLLAGFVVFSVLGFLSEKSGIPVESVATGGAGLAF 348

Query: 381 IVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFI 440
           + YPE +  LP+  LW+++FF ML  LG+DS F  +E + ++ILD +   R  K  +  I
Sbjct: 349 VTYPEAIALLPVPQLWALMFFFMLFLLGIDSVFVQLEAIMSSILDEWYWVRSHKCKLTLI 408

Query: 441 VAVFGYLG-GLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQR 499
             +  +LG   I  TN GM+ LQL D Y++  +V++I + E I++AWIYG + F  D++ 
Sbjct: 409 SCLI-FLGLSSIMCTNGGMFILQLFDWYSSAIAVIVICLVEIIMVAWIYGIKNFMLDVEF 467

Query: 500 MIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGW 554
           M+G++  L+   W  +W+++TP  ++FIL+ + +  +  +Y +  YP WA  +GW
Sbjct: 468 MLGKRPTLY---WRIVWQVVTPVIIIFILITSIVFIRTITYNNIPYPQWAIIIGW 519


>UniRef50_Q4F9L7 Cluster: High-affinity octopamine transporter
           protein; n=12; Arthropoda|Rep: High-affinity octopamine
           transporter protein - Ostrinia nubilalis (European corn
           borer)
          Length = 745

 Score =  409 bits (1008), Expect = e-113
 Identities = 217/559 (38%), Positives = 315/559 (56%), Gaps = 34/559 (6%)

Query: 4   QACLKGDEEKSKAPLS-EEIEPERGN--WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNG 60
           + C+  D  K     S +  +P+ G   W    DF            NVWRFPYLCY NG
Sbjct: 154 EECIYSDSSKRVRTSSLKPGDPDDGRETWGTGADFLLSIIGFAVDLANVWRFPYLCYRNG 213

Query: 61  GGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVM 120
           GGAFLIP+T+ML+   +PL +MEL  GQY   GP+ ++ K CPLF+G+G+  V+V+  V 
Sbjct: 214 GGAFLIPYTLMLIFGAVPLFYMELILGQYNRQGPITIW-KICPLFKGVGFCAVMVAFYVS 272

Query: 121 LYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQC 180
            YYN+II W  +++  S  S   +LPW +C   W+T  C+   +A      N T    Q 
Sbjct: 273 FYYNVIIGWAFYFLVSSARS---ELPWVHCDNAWNTDQCW---DAARLNNTNRTEIPYQG 326

Query: 181 FNQSYSVSHNITALAKTALRRPPAEEYFTNQVLGL--SSGIEETGEIRLGMAMCLLAAWV 238
                 +SH             PA E+F   VL +  S G+ + G  +  + +CL   +V
Sbjct: 327 -----PLSHFT-----------PASEFFHRAVLEMQHSEGLNDLGFPKWQLTVCLGLVYV 370

Query: 239 IVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQ 298
            ++L L KGV+SSGKVV+ TA  PYVVL IL  RG+ LPGA  GI +YL P+ ++L + Q
Sbjct: 371 TLYLSLFKGVKSSGKVVWMTATMPYVVLSILLARGLLLPGATRGIAYYLQPELTRLKDTQ 430

Query: 299 VWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIG 358
           VW DAAVQIF+++   +G  ++ +SYN F NNCY D L+  + N  TSFF+G VIF+ +G
Sbjct: 431 VWVDAAVQIFYSVGAGFGVHLSYASYNTFHNNCYRDCLVTTLVNCFTSFFSGFVIFTYLG 490

Query: 359 FLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMET 418
           F++++  V +  V  +G GL F VYPE V  LP + LW++LFF ML+ LGLDS    +E 
Sbjct: 491 FMSYKQGVPISSVATEGPGLVFQVYPEAVATLPGASLWAMLFFFMLIMLGLDSGMGGLEC 550

Query: 419 VTTAILD--RFPNFRQ-KKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLI 475
           V T +LD  R    +  ++    F+V    +    I  T  G+Y   L+D YAA  S+L 
Sbjct: 551 VITGLLDAARASGAKHLRREHFTFVVVCVSFCVACINVTPGGIYMFHLLDTYAAGISLLC 610

Query: 476 IAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEY 535
            A+ E + ++W YG +KF  D++ M+G +  L+   W   W+ ++P  ++ ++VF  +  
Sbjct: 611 SALFEAVAVSWFYGLKKFSDDVEEMLGFRPGLY---WRICWKFVSPTFIIGVVVFGLLYQ 667

Query: 536 KPASYGHYVYPMWADAVGW 554
           +P  Y  Y YP WA  +GW
Sbjct: 668 QPLVYQTYTYPQWAVVLGW 686


>UniRef50_UPI000051A91B Cluster: PREDICTED: similar to inebriated
           CG15444-PB, isoform B; n=2; Endopterygota|Rep:
           PREDICTED: similar to inebriated CG15444-PB, isoform B -
           Apis mellifera
          Length = 888

 Score =  409 bits (1007), Expect = e-112
 Identities = 197/538 (36%), Positives = 319/538 (59%), Gaps = 36/538 (6%)

Query: 23  EPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFM 82
           +  R +W  +  F            N+WRFPYLCY +GGG FL+P+ ++L++ G+PL++M
Sbjct: 297 QSRRPHWANKMQFVLACIGYSVGLGNIWRFPYLCYKSGGGVFLVPYFLILIVCGVPLLYM 356

Query: 83  ELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIF 142
           ELS GQ+   GP+    + CPLF+G G   V++S ++  Y+N+IIA+ I+Y   +F +  
Sbjct: 357 ELSIGQFTRRGPIGALGQICPLFKGAGLSSVVISFLMSTYHNVIIAYAIYYFFTAFRA-- 414

Query: 143 YQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRP 202
            + PW +C+  W+T  C+                       +YS   N T   +    R 
Sbjct: 415 -KQPWSDCENSWNTLACWL---------------------PTYSGIDNRT---RPNASRT 449

Query: 203 PAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFP 262
           PAEE+F N+VL +S+GIEE+G +R  +  CL+ AW++V+  + K ++SS +V Y TA  P
Sbjct: 450 PAEEFFDNKVLQISNGIEESGPLRWELIACLITAWIMVYFSVWKSIKSSAQVRYLTATLP 509

Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322
           ++++V+   R +TL GA  G+ F+  P +  LA+A+VW  A  QIF ++  A+G +I  +
Sbjct: 510 FLLIVVFLMRSLTLEGADKGLQFFFHPRWELLADAKVWIYATAQIFNSVGIAFGSMICFA 569

Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIV 382
           SYNKF N   ID++ V++ N  +S   G+  F+ IG +A E N+SV+ V+  G GL F++
Sbjct: 570 SYNKFHNTILIDTMAVSLINGFSSLLVGIFSFATIGNIALEQNMSVEDVLTDGPGLVFVL 629

Query: 383 YPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK----KGWVV 438
           YP+ + ++P S +W++LFF ML+ L L+SQFA++E V T+I D FP + ++       +V
Sbjct: 630 YPQALAKMPASQVWAVLFFFMLVCLSLNSQFAIVEVVVTSIQDGFPKWVKRHLTCHEMLV 689

Query: 439 FIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQ 498
            ++ V  +L GL   +  G+Y+ QL+D YAA+ S++ +A  E I I+W YG  + C +++
Sbjct: 690 LLICVISFLFGLPNISQGGIYFFQLIDHYAASISIMFLAFFEVIAISWFYGVRRLCNNVK 749

Query: 499 RMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASY--GHYVYPMWADAVGW 554
            M GR    +   +   W I  P  ++ + VF+ I+Y+P +Y  G Y YP WA+A+GW
Sbjct: 750 EMTGRVPSSY---FRFCWLIAAPFLIMAVWVFSLIDYEPPTYHNGEYKYPWWAEAIGW 804


>UniRef50_Q9N3C7 Cluster: Transporter; n=3; Caenorhabditis|Rep:
           Transporter - Caenorhabditis elegans
          Length = 671

 Score =  407 bits (1001), Expect = e-112
 Identities = 215/614 (35%), Positives = 332/614 (54%), Gaps = 39/614 (6%)

Query: 11  EEKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTV 70
           +E   A L       R  W  + +F            N+WRFP +CY +GGGAFLIP+ +
Sbjct: 85  KEGRVAALRRRSSMVRDKWATKMEFLLAVVGYAVDLGNIWRFPSVCYKHGGGAFLIPYFI 144

Query: 71  MLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWT 130
           ML+I GLP+ +MEL  GQ+   G V+++ K CPLFRG+GYG+  + + + ++YN IIA  
Sbjct: 145 MLMIGGLPMFYMELVLGQFHRSGCVSIWRKVCPLFRGIGYGICCICTFIAIFYNAIIAQA 204

Query: 131 IFYMTVSFSSIF-YQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSH 189
           +++  VS S I+  ++PW +C   W+T  C     +D+                  ++S 
Sbjct: 205 VYFAIVSLSKIWDSEVPWASCGNPWNTPRC-----SDDLNV---------------TISR 244

Query: 190 NITALAKTALRRPPAEEYFTNQVLGL--SSGIEETGEIRLGMAMCLLAAWVIVFLCLCKG 247
           N T L        P+EEY+  +VL +  S+G ++ G ++  MA+CLLA +++V+  L KG
Sbjct: 245 NGTPLTT------PSEEYYLYKVLEVQKSTGFDDLGGVKTSMAVCLLAVFIMVYFALWKG 298

Query: 248 VQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQI 307
            QSSGK+V+ TA  PY++L IL  RG+ LPGA  G+ +Y+TPDF +L +  VW  AA QI
Sbjct: 299 PQSSGKIVWVTATAPYIILSILLIRGLLLPGAKNGLYYYVTPDFEKLKDPAVWSAAATQI 358

Query: 308 FFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVS 367
           FF+L P +G L+ LSSYN F+NNCY D++  ++ N ATSFF+G V+FS +G+++   N  
Sbjct: 359 FFSLGPGFGVLLALSSYNDFNNNCYRDAVTTSIINCATSFFSGCVVFSTLGYMSLLTNKP 418

Query: 368 VDRVV-DQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDR 426
           ++ VV +  A L FIVYP+ +  +  S  WS +FFVML+TLG+DS FA +E   T   D 
Sbjct: 419 INEVVGEHDASLIFIVYPQALATMDYSCFWSFIFFVMLITLGIDSTFAGIEAFITGFCDE 478

Query: 427 FPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAW 486
                + + W V ++ +  Y       +  G + +  +D+Y  + SVL I   E I + W
Sbjct: 479 SRFLSKNRKWFVLVICIIYYFLSFPAISYGGQFVIPFLDEYGVSLSVLFIVTCEMIAVCW 538

Query: 487 IYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPA--ALVFILVFNWIEYKPASYGHYV 544
            YG ++F  DI+ M+G    ++   W   W   +P   +++FI+      +KP     Y 
Sbjct: 539 FYGVDQFSKDIRAMLGFYPGIY---WRVCW-TCSPVFISVIFIMTVYNSSFKPIQMASYT 594

Query: 545 YPMWADAVGWTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWGQAGSTATC 604
           +P W+  +GW                 + SG    T+ E+ R    P +    A S A  
Sbjct: 595 FPWWSVILGWFLRLLSVLAIPVFAIIYLLSGTG--TLYERFRWAITPQQRRNSATSLAAD 652

Query: 605 LSTLRVETELSPPV 618
             T  +++ L  P+
Sbjct: 653 -PTQIIDSSLLDPI 665


>UniRef50_Q7YZB6 Cluster: Sodium and chloride dependent proline
           transporter; n=2; Manduca sexta|Rep: Sodium and chloride
           dependent proline transporter - Manduca sexta (Tobacco
           hawkmoth) (Tobacco hornworm)
          Length = 556

 Score =  405 bits (998), Expect = e-111
 Identities = 202/506 (39%), Positives = 297/506 (58%), Gaps = 34/506 (6%)

Query: 29  WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQ 88
           W  + ++            N+WRFPYLCY NGGGAFLIP+ + L+I G+PL+++E + GQ
Sbjct: 9   WGSQLEYLLSCLGYAVGIGNLWRFPYLCYRNGGGAFLIPYFLTLIICGIPLVYLETTLGQ 68

Query: 89  YAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQ 148
           +A+ G ++V+N   PLF+G GY +++++ I  +Y++ I+++ I Y+  S SS    LPWQ
Sbjct: 69  FASAGCISVFN-INPLFKGAGYAVIVLNVIASIYFSAIMSYPILYIYHSMSS---PLPWQ 124

Query: 149 NCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAEEYF 208
           +C   W+T +C            NG+                IT          P +EYF
Sbjct: 125 SCGNSWNTVNCTEITGNSSFFTSNGS----------------ITT---------PEDEYF 159

Query: 209 TNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVI 268
              +L +S  I   G I   +  C L  W++V+LC+C GV+S GK+VYFT LFPYVVL +
Sbjct: 160 HRHLLQVSPNINHIGSIVAPVFWCNLICWILVYLCICNGVKSVGKIVYFTVLFPYVVLSV 219

Query: 269 LFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFS 328
           LF RG+TLPGA  GI+FY+ PD++QLA  +VW DAA QIFF+L P WGGL+++SS+NKF 
Sbjct: 220 LFVRGITLPGAWKGIMFYILPDWAQLAKPKVWADAATQIFFSLGPGWGGLVSMSSFNKFH 279

Query: 329 NNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVT 388
            N    S+I+ + N ATS +AG V+FSV+GF A   NV V +V   G GLAF+ YP  VT
Sbjct: 280 YNNLRSSMIIPIVNSATSIWAGFVVFSVLGFAAERTNVPVSQVATAGPGLAFVTYPATVT 339

Query: 389 RLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLG 448
            +P   LW+I FFVML  LG+D+ F  +E +   +LD FP F+ +K  + FI  V  +  
Sbjct: 340 MMPAPNLWAITFFVMLFFLGIDTMFVTIEAIIAGLLDEFPRFKSRKRIIAFITCVVLFSF 399

Query: 449 GLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLW 508
            +I  T  G++ + L+D + A   V ++   E  +IA +Y  E F  D+  M GR  +  
Sbjct: 400 SIICNTEGGLHVIGLLDSHVAILCVPLVCALE--IIAAVYTYENFSFDVLFMTGRPLR-- 455

Query: 509 VYLWSAMWRIITPAALVFILVFNWIE 534
             +W  +WR +    L+ I +++ +E
Sbjct: 456 -RIWMVLWRYVILLILLVITLYSLLE 480


>UniRef50_A4QNW3 Cluster: Transporter; n=10; Clupeocephala|Rep:
           Transporter - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 609

 Score =  401 bits (987), Expect = e-110
 Identities = 212/544 (38%), Positives = 320/544 (58%), Gaps = 40/544 (7%)

Query: 16  APLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIA 75
           A + ++    R  W  R +F            NVWRFPYLCY +GGGAFLIP+ +ML + 
Sbjct: 44  AKVEQQAAEPRETWGRRLEFVLATIGYAVGLGNVWRFPYLCYRSGGGAFLIPYMIMLFLC 103

Query: 76  GLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMT 135
           G+PL+FME + GQY  LGPV    + CPLF+G+G   V++ S V+  Y         Y  
Sbjct: 104 GIPLLFMEFTVGQYTRLGPVHALAQICPLFKGVGLATVVI-SYVLCTY---------YNV 153

Query: 136 VSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALA 195
           +   +++Y L              +S+  +   ++ N T+      N S     N T L 
Sbjct: 154 LMTWALYYLL--------------HSFSPSLPWQSCNNTW--NTVANCSTGFPGNATHLQ 197

Query: 196 KTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVV 255
             +      +++F ++VL ++SGIE  G +R  +   L+ AW IV+ C+ KGV+S+GKVV
Sbjct: 198 SAS------QQFFDHKVLEMTSGIERAGGVRWELFGLLVLAWGIVYFCIFKGVKSTGKVV 251

Query: 256 YFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAW 315
           YFTA FPY +L  L    V LPGA  GILF+L P++S+L   QVW +AA QIF ++  ++
Sbjct: 252 YFTATFPYFILFALLVNNVQLPGAKNGILFFLMPNWSKLLEVQVWVNAAAQIFNSIGISF 311

Query: 316 GGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQG 375
           G +I+++SYNK++NN   D+ IV+++N ATS  AG VIFS IG++AH  N+ VD +   G
Sbjct: 312 GSMISMASYNKYNNNILRDTFIVSLANSATSIVAGFVIFSAIGYMAHIHNLPVDDIATDG 371

Query: 376 AGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFP----NFR 431
            GL F+VYPEV + +P+S LW+ LFF+MLL LGLDSQFA++E   T I+D F        
Sbjct: 372 PGLVFVVYPEVFSTMPVSQLWAPLFFIMLLCLGLDSQFAMVEVAVTFIMDGFGRKALKVF 431

Query: 432 QKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAE 491
           ++K  +V  V  FG+L G+   T  G+Y  QLMD Y A  S++ +A  E + +  I+G +
Sbjct: 432 KRKELIVLAVCSFGFLLGIPHITRGGIYVFQLMDHYTAVVSLMFLAFFEVLAVTLIFGVK 491

Query: 492 KFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYG-HYVYPMWAD 550
           +    ++ M+G++  L+   +   W+ ++P  ++ IL+ + ++Y PA YG  Y YP+WA+
Sbjct: 492 RLSVMVENMLGKKPNLF---FRICWQYLSPMLVLGILISSIVQYTPARYGKSYTYPLWAE 548

Query: 551 AVGW 554
            +GW
Sbjct: 549 LLGW 552


>UniRef50_Q0PKT4 Cluster: High-affinity octopamine transporter; n=1;
           Lumbricus terrestris|Rep: High-affinity octopamine
           transporter - Lumbricus terrestris (Common earthworm)
          Length = 673

 Score =  400 bits (986), Expect = e-110
 Identities = 217/560 (38%), Positives = 311/560 (55%), Gaps = 44/560 (7%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           R  W  + DF            NVWRFPYLCY NGGGAFLIP+  ML+   +PL  MEL 
Sbjct: 108 RETWNKKADFLLSIIGFAVDLANVWRFPYLCYTNGGGAFLIPYFTMLICGAVPLFLMELI 167

Query: 86  FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQL 145
            GQY   G + V+ K  PLF+G+G    +++  V  YYN+IIAW+++Y+  SF+   Y L
Sbjct: 168 MGQYQRQGAITVW-KIAPLFKGIGICQCLIAFYVAFYYNVIIAWSLYYLVSSFA---YVL 223

Query: 146 PWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAE 205
           PW  C   W+T +C      D     NG            S S+  T    TA     A 
Sbjct: 224 PWTTCNNTWNTMNCI-----DGSAMANG------------STSNEST----TA-----AA 257

Query: 206 EYFTNQVLGL--SSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPY 263
           E+F   VLGL  SSGI + G  R  + +CL   +++++  L KGV SSGKVV+ TA  PY
Sbjct: 258 EFFERGVLGLQESSGIGDIGLPRKYLVLCLFGVFIMIYFSLWKGVHSSGKVVWVTATMPY 317

Query: 264 VVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSS 323
           VVL IL  RG+ LPGA  GI++Y+TP   +L + +VW DAA+QIF+++   +G  I  +S
Sbjct: 318 VVLSILLVRGLMLPGASIGIMYYITPKLERLGDPKVWIDAAIQIFYSVGAGFGVHIAFAS 377

Query: 324 YNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVY 383
           YNK ++NCY D L     N  TS F+G VIFS +G+++      +  V  +G GL F+VY
Sbjct: 378 YNKINSNCYRDCLATVCVNSFTSLFSGFVIFSYLGYMSIRQKKDISVVAAEGPGLVFVVY 437

Query: 384 PEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNF--RQKKGWVVFI- 440
           PE +  LP S  WSILFFVML+TLG+DS    +E + T + D + +   R + G      
Sbjct: 438 PEAIATLPGSVGWSILFFVMLITLGIDSAMGGLEALLTGLSDEWKSVIKRYRFGREALTG 497

Query: 441 VAVFG-YLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQR 499
           + VFG +L  L   TN GMY + + D++AA  ++L     + + ++W YG E+FC D ++
Sbjct: 498 MVVFGAFLFALPNVTNGGMYLVTIWDRFAAGTAILFGVFSQAVAVSWFYGMEQFCKDAEQ 557

Query: 500 MIGRQSKLWVYLWSAMWRIITPAALVFILV-----FNWIEYKPASYGHYVYPMWADAVGW 554
           ++G +  L+   W   W+ I+P  ++ I++     F  +EYK  + G+Y +P+WA+ VGW
Sbjct: 558 ILGFRPNLY---WRLTWKFISPIFILGIVISSVVSFEPLEYKTYTMGNYTFPVWANVVGW 614

Query: 555 TXXXXXXXXXXXXXXDQICS 574
                           Q+CS
Sbjct: 615 GIALSSMSFIPIVAVYQLCS 634


>UniRef50_O76689 Cluster: Sodium-dependent acetylcholine
           transporter; n=2; Caenorhabditis|Rep: Sodium-dependent
           acetylcholine transporter - Caenorhabditis elegans
          Length = 714

 Score =  397 bits (977), Expect = e-109
 Identities = 185/575 (32%), Positives = 323/575 (56%), Gaps = 10/575 (1%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           RGNW+ + D+            + W+FP+L + +GG AFL+P+  ML +A LP+ FME+ 
Sbjct: 64  RGNWSNKSDYLLAVIGFTAGVGSFWKFPFLVFQHGGAAFLVPYLCMLCLASLPMFFMEMV 123

Query: 86  FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQL 145
            GQ+++   ++V+ K  PLF+G+G+  V +S    +++N+I AWT+FY+  SFS   + +
Sbjct: 124 LGQFSSSAAISVW-KVVPLFKGIGFAQVTISGFFAVFFNIISAWTLFYLINSFS---FSI 179

Query: 146 PWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAE 205
           PW NC   WS ++C +     +C+  NGT  +       ++ S+  T +    L   P+ 
Sbjct: 180 PWSNCANSWSGENC-TLGTRIQCKEMNGTLLVNGSCIVEHASSNETTVIPLHDLGSIPSL 238

Query: 206 EYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVV 265
           +YF N VL LS G+++ G +   + +C+LA W+ VFLCL +GV+SSGKVVY   + P+++
Sbjct: 239 KYFQNDVLMLSKGVDDFGTLNWYLGLCVLACWIAVFLCLFQGVKSSGKVVYVAVIVPFII 298

Query: 266 LVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYN 325
           L +L  R +TL G++  + ++LTP +  L +  VWG+AAVQ F+++S   GGL T++SY+
Sbjct: 299 LTVLLTRLLTLDGSLAAVFYFLTPKWEILMDLHVWGEAAVQAFYSVSCCSGGLFTIASYS 358

Query: 326 KFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRV-VDQGAGLAFIVYP 384
           +F NN Y D  +V + ++  S    L+ FS IGF  +E  +S+D+  +  G  L F+   
Sbjct: 359 RFHNNIYKDIWLVLIVDVIVSLVGCLLTFSAIGFTCYEFAISLDKFHIRDGFHLVFVFLA 418

Query: 385 EVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFP-NFRQKKGWVVFIVAV 443
           E +  + ++PL++ LFF+M+L +   +Q  ++ET+ ++I D +P   R+ +  V+  V  
Sbjct: 419 EALAGVSVAPLYAGLFFIMILLVVHATQMFVVETIVSSICDEYPERLRRNRRHVLTTVCA 478

Query: 444 FGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGR 503
              L  + F  +SG++W++L+ ++   W +++IA  EC+ I W+YG +    + + ++G 
Sbjct: 479 LFILLSIPFCLSSGLFWMELLTQFVLTWPLVVIAFLECMAINWVYGVDNMLDNAKWIVGY 538

Query: 504 QSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGWTXXXXXXXX 563
               +++ W  +++ I P   + IL F W+++    Y  Y +P W+    W         
Sbjct: 539 WPPCYIF-WKILFKFICPMVYLAILCFLWLDWNSIQYESYQFPYWSILTAWCIASFPLIL 597

Query: 564 XXXXXXDQICSGPDDLTIMEKARVLARPTEEWGQA 598
                  Q C      TI +K   +  P + WG A
Sbjct: 598 IPIVGIWQFCIAKG--TITQKWWRVLYPDDAWGPA 630


>UniRef50_Q9VR07 Cluster: Sodium- and chloride-dependent GABA
           transporter ine; n=7; Endopterygota|Rep: Sodium- and
           chloride-dependent GABA transporter ine - Drosophila
           melanogaster (Fruit fly)
          Length = 943

 Score =  393 bits (967), Expect = e-108
 Identities = 208/554 (37%), Positives = 317/554 (57%), Gaps = 40/554 (7%)

Query: 10  DEEKSKAPLSEE---IEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLI 66
           D++ S   +S+E   ++P + +W  +  F            NVWRFPY+CY +GGG FL+
Sbjct: 318 DDDDSYLDMSDETAQLKPRQQHWANKMQFVLACIGYSVGLGNVWRFPYMCYKSGGGVFLV 377

Query: 67  PFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLI 126
           P+ ++L I  +PL+FMELS GQY   GP+    + CPLF+G G   V+VS ++  YY++I
Sbjct: 378 PYCIILFICSIPLLFMELSVGQYTGRGPIGALGQLCPLFKGAGLASVVVSFLMSTYYSVI 437

Query: 127 IAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYS 186
           I ++I+Y    F+S   ++P       W            +C   N  +    C+     
Sbjct: 438 IGYSIYYF---FTSFKTEMP-------WI-----------DC---NNRWNTPDCWVPQRK 473

Query: 187 VSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCK 246
               I A A     R P+EE+F N+VL +S G+E  G +R  +  CL+ AW++V+    K
Sbjct: 474 ---GINASAPDT-SRTPSEEFFENKVLQISGGLEYPGMMRWELFACLICAWLMVYFATWK 529

Query: 247 GVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQ 306
            ++SS KV YFTA FP+V+++IL  R VTL GA  G+ F+  P +S+L NA VW +AA Q
Sbjct: 530 SIKSSAKVRYFTATFPFVLIIILMVRAVTLDGAAEGLRFFFRPKWSELKNANVWINAASQ 589

Query: 307 IFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNV 366
            F +L   +G +I+ +SYNK++NN   D++ V+  N+ TS   G+  FS +G LA E N 
Sbjct: 590 NFNSLGITFGSMISFASYNKYNNNILRDTVAVSAVNMITSLLVGIFAFSTLGNLALEQNT 649

Query: 367 SVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDR 426
           +V  V+  G G+ F+VYP+ + ++P + LW+++FF MLL LGL+SQFA++E V T+I D 
Sbjct: 650 NVRDVIGDGPGMIFVVYPQAMAKMPYAQLWAVMFFFMLLCLGLNSQFAIVEVVVTSIQDG 709

Query: 427 FPNF-RQKKGW---VVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECI 482
           FP + ++  G+   VV  V V   L G+      G+Y+ QLMD YAA+ +++ +A  + I
Sbjct: 710 FPRWIKRHLGYHEIVVLFVCVISCLFGMPNIIQGGIYYFQLMDHYAASVTIMFLAFCQMI 769

Query: 483 LIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASY-- 540
            IAW YG  +   ++++M G+      YL S  W ++ P  L  I V + I Y   +Y  
Sbjct: 770 AIAWFYGTGRLSKNVKQMTGKAPSF--YLRSC-WLVLGPCLLFAIWVLSLINYHEPTYHN 826

Query: 541 GHYVYPMWADAVGW 554
           G Y YP WA  +GW
Sbjct: 827 GRYTYPDWAYGIGW 840


>UniRef50_O17372 Cluster: Sodium:neurotransmitter symporter family
           protein 3; n=2; Caenorhabditis|Rep:
           Sodium:neurotransmitter symporter family protein 3 -
           Caenorhabditis elegans
          Length = 600

 Score =  388 bits (954), Expect = e-106
 Identities = 201/552 (36%), Positives = 310/552 (56%), Gaps = 28/552 (5%)

Query: 7   LKGDEEKSKA--PLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAF 64
           L  DE K+K         EP+RG WTG+FDF            NVWRFPYLCY NGGG+F
Sbjct: 9   LPTDEAKAKELEQSQHSEEPDRGQWTGKFDFLMSMVAYAVGLGNVWRFPYLCYKNGGGSF 68

Query: 65  LIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYN 124
           L+ + +   +A +P+  ME++ GQY   G + ++   CPLFRG+G G V+++ + + Y+ 
Sbjct: 69  LVVYMIFFCLAAVPIFLMEVTVGQYLQKGAMEMW-LMCPLFRGVGIGNVVIAFMCIAYFC 127

Query: 125 LIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQS 184
           +I+AW +FYM    SSI +  PW+ C   W+   C + +E       N T   R     +
Sbjct: 128 VIVAWAMFYM---ISSIAWVFPWETCNNYWNDATCVTGKE-------NFTELARIKALVA 177

Query: 185 YSVSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCL 244
            +  H  T++          E+++  +VL  +  I E G I+  +   + AAW+IV+  L
Sbjct: 178 SAGGHTQTSV----------EQFWEKRVLHDTGDISEFGGIQWELFFIMAAAWLIVYFAL 227

Query: 245 CKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAA 304
            KG+  + K VYF ALFPYV++ IL  RG+TL GA TGI FYL P+ ++L +  VW DA 
Sbjct: 228 WKGITQARKFVYFCALFPYVLIFILLIRGLTLEGAGTGIYFYLKPNATRLLDTAVWKDAG 287

Query: 305 VQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHEL 364
            Q+F++    +G LI L S+NKF++NC+ D++ +   N  TS  AG  +FS++G+++H  
Sbjct: 288 TQVFYSYGVGFGALIALGSHNKFNHNCFKDAITMCFINGCTSITAGFAVFSILGYMSHVA 347

Query: 365 NVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAIL 424
              +  +V  G GLAF+ YPEV + LP+  ++++LFF+M+  LGLDSQ  +ME + TA+ 
Sbjct: 348 QKDISEIVKPGVGLAFLAYPEVASNLPMKQVFAVLFFLMITILGLDSQVCMMEGLFTALE 407

Query: 425 DRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKY-AANWSVLIIAIGECIL 483
           D FP  R+ K   + I  +F +  G+   T+SG +WL L D Y A+ +++L +   E + 
Sbjct: 408 DAFPILRKYKKQSLGIFCLFFFCIGIPMVTHSGSHWLTLFDAYGASGYALLFVVFFEVVG 467

Query: 484 IAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASY-GH 542
           +A+ +GA      +  MIG      +     +W+   PA  + + VF  + Y P  Y   
Sbjct: 468 LAYGFGAHNIRKALHEMIGVTLPKGI---EYVWKFCAPATSLVLFVFCVVYYHPVKYPDG 524

Query: 543 YVYPMWADAVGW 554
             +P WA+A GW
Sbjct: 525 KDFPFWANAFGW 536


>UniRef50_Q7K330 Cluster: Transporter; n=11; Diptera|Rep:
           Transporter - Drosophila melanogaster (Fruit fly)
          Length = 654

 Score =  384 bits (946), Expect = e-105
 Identities = 198/576 (34%), Positives = 313/576 (54%), Gaps = 36/576 (6%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           +R +W    +F            NVWRFP+    NGGGAF+IP+ ++L++ G P+ ++E+
Sbjct: 73  KRDSWNNDIEFLMSCIALSVGLGNVWRFPFTALENGGGAFVIPYLIVLILVGKPVYYLEM 132

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
             GQ+++ G V VY+ F P+ RG+GYG V+ + IV  YY  ++A T+ Y   SF   +  
Sbjct: 133 LLGQFSSRGSVKVYD-FSPIMRGIGYGQVLATGIVTTYYATLMALTLRYFVDSF---YPT 188

Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPA 204
           LPW  C+ EW T                      +C +     +   T+LA + +R   A
Sbjct: 189 LPWSYCREEWGT----------------------ECLDSGPQEASRATSLAGSGVRTTSA 226

Query: 205 EEYFTNQVLGLSSGIEE-TGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPY 263
           E YFTN +L   + I++  G     +A+ L  AW+++   + KGV+SSGK  YF ALFPY
Sbjct: 227 EFYFTNIILREKASIDDGIGYPSWSLALALAVAWIVIAGIMFKGVKSSGKASYFLALFPY 286

Query: 264 VVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSS 323
           VV+++L  R +TLPGA  G+L++L P + +L   QVW  A  Q+FF+L+  +G +I  +S
Sbjct: 287 VVMLVLLVRALTLPGAFDGVLYFLRPQWHKLLEPQVWYAAVTQVFFSLAICFGNIIMYAS 346

Query: 324 YNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVS-VDRVVDQGAGLAFIV 382
           YN+F +N Y D+ IV   +  TS  +G++IF ++G LA+E N + +  VV+ G GLAFI 
Sbjct: 347 YNRFGHNIYRDANIVTTLDTFTSLLSGVIIFGILGNLAYENNTTDIASVVNGGPGLAFIS 406

Query: 383 YPEVVTRLPISP-LWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFI- 440
           YP+ + +    P L+S+LFF+ML  LG+ S   +   ++T I D+F +    K W V + 
Sbjct: 407 YPDAIAKFKWLPQLFSVLFFLMLFVLGIGSNVGMASCMSTVIKDQFGHL---KNWTVVVG 463

Query: 441 VAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRM 500
           +A+ GY  GL++ T  G + L L+D +   +  L++AI E + IAWIYG ++ C D++ M
Sbjct: 464 IAIVGYFLGLLYITPGGQFLLNLVDYFGVTFVALVLAIFELVTIAWIYGVKRLCRDVEFM 523

Query: 501 IGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGWTXXXXX 560
           IG ++ L+   +   W ++TP  ++ IL++  + Y+P  Y  Y Y       GW      
Sbjct: 524 IGIKTSLY---YRICWAVVTPLLMLTILIYTLVLYEPLKYKDYTYQSGVYVFGWCLSAFG 580

Query: 561 XXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWG 596
                      +   P  L +  + R    P   WG
Sbjct: 581 VGQVLFWAIPAVRKQPSHLGLWARIRKAFEPLPNWG 616


>UniRef50_Q9W4C5 Cluster: Uncharacterized sodium-dependent
           transporter CG3252; n=9; Endopterygota|Rep:
           Uncharacterized sodium-dependent transporter CG3252 -
           Drosophila melanogaster (Fruit fly)
          Length = 641

 Score =  384 bits (946), Expect = e-105
 Identities = 205/583 (35%), Positives = 312/583 (53%), Gaps = 18/583 (3%)

Query: 19  SEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLP 78
           +E+   ER NW    +F            NVWRFP+  Y NGGGAFLIP+ ++L + G P
Sbjct: 31  AEKPTAERTNWGNGLEFLMSCISVSVGLGNVWRFPFTAYENGGGAFLIPYIIVLFLIGKP 90

Query: 79  LMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSF 138
           + ++E+  GQ+ + G V +++   P F G+GYG    +  ++ YY+ ++A T++Y+ VSF
Sbjct: 91  MYYLEMIMGQFTSQGTVKIWS-VVPGFVGVGYGQAFGTICIISYYSSLLALTLYYLFVSF 149

Query: 139 SSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTA 198
            S   +LPW  C+ EW+  +C +    +  +       L    N+S      I A  +T 
Sbjct: 150 QS---ELPWSYCRDEWT--NCVNSRPQEYVDNLLTGVSLA---NESARNLSGIVANDETE 201

Query: 199 LRRPPAEEYFTNQVLGLSSGIEE-TGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYF 257
             +  +E YF N V+     I +  G+    + + L  AWV++FL + +GV+SSGK  YF
Sbjct: 202 KLQSSSELYFLNVVIKEKLDISDGVGDPDWKLTLALFVAWVVIFLVIMRGVKSSGKAAYF 261

Query: 258 TALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGG 317
            ALFPYVVL +L  R VTL GA  GILF+L P + +L N  VW +A VQ FF+L+   G 
Sbjct: 262 LALFPYVVLFVLLIRAVTLEGARDGILFFLEPQWGELLNPTVWKEAVVQCFFSLAVGSGP 321

Query: 318 LITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNV-SVDRVVDQGA 376
           +I  +SYN+F +  Y D++IV   +  TS   G+ IF+++G LAH L + ++  VV  G 
Sbjct: 322 IIMFASYNRFDHGIYRDAMIVTTLDTLTSLLGGITIFAILGNLAHNLQIENIRDVVRSGT 381

Query: 377 GLAFIVYPEVVTRLPISP-LWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKG 435
           GLAFI YP+ +++    P L+S+LFF ML  LG+ S  AL  T+ T I D+F  ++  K 
Sbjct: 382 GLAFISYPDAISKFQAVPQLFSVLFFFMLFVLGIGSIVALQSTIVTIICDQFKGWKYWK- 440

Query: 436 WVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCG 495
            V    +V G+L GL++ T  G + L L+D Y   + V I+AI E   I W+YG + FC 
Sbjct: 441 -VALTTSVCGFLMGLVYVTPGGQWILTLVDFYGGTYVVFILAIFELAGIVWVYGLQNFCD 499

Query: 496 DIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGWT 555
           DI+ M  R+  L+   W   W   TP  ++ I +++ +  +P  Y    +P  A+  GW 
Sbjct: 500 DIEFMCNRRVSLY---WRVCWSFFTPVMMIIIFIYSMVTIEPIKYSELYFPEAANIAGWL 556

Query: 556 XXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWGQA 598
                           I   P   T  +  +   +P++ WG A
Sbjct: 557 LFAIGAAQFPLWGLWYISRHPQG-TYWKSLKASLKPSDRWGPA 598


>UniRef50_UPI00015B40E0 Cluster: PREDICTED: similar to glycine
           transporter; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to glycine transporter - Nasonia vitripennis
          Length = 584

 Score =  378 bits (931), Expect = e-103
 Identities = 200/472 (42%), Positives = 283/472 (59%), Gaps = 41/472 (8%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           +R  W    +F            NVWRFPYL Y NGGGAFLIPF +ML+  GLP+ F+EL
Sbjct: 34  QRQGWANPLEFVLSCIGYAVGIGNVWRFPYLVYRNGGGAFLIPFVLMLLTMGLPIFFLEL 93

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
             GQY  LGP   Y +  P F+GLGY  ++V ++V +YY +II+WT+FY   SFSS   +
Sbjct: 94  IVGQYVGLGPTEAYARMAPAFQGLGYCTIVVIALVTIYYMVIISWTLFYTFASFSS---K 150

Query: 145 LPWQNCKAEWS--------------TKHCYSYEEADECEAQNG--TYYLRQC-----FNQ 183
           L W  C  E++              T HCYS  +  EC A+     YY R C     F +
Sbjct: 151 LAWAYCDNEFNSPSERRHLRSSMLITCHCYSSLQDAECRAERPDLVYYNRSCMGIEAFCR 210

Query: 184 SYSVSHNIT---------------ALAKTALRRPPAEEYFTNQVLGLSSGI-EETGEIRL 227
           S+ ++ N++                L     R   +EE++ + VLG+     E+ G +R 
Sbjct: 211 SFGLASNLSDPTHCYKVGGNGPGIELRHLYNRTLSSEEFYNDYVLGIRDAKWEDWGGMRW 270

Query: 228 GMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYL 287
            +  C+  AW++ +LCL KG+QS GKVVYFTALFPY VL+    RG TL GA+ GIL+Y+
Sbjct: 271 ELLGCISLAWLVCYLCLIKGIQSVGKVVYFTALFPYFVLIAFMIRGATLEGAVDGILWYI 330

Query: 288 TPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSF 347
           +P +S L +A+VW DAA Q+F++L    G L+TL+SY+ FSNNC+ D++ V ++N+ TS 
Sbjct: 331 SPRWSYLMDARVWADAASQVFYSLGIGCGSLVTLASYSSFSNNCHRDAVFVTLTNLLTSV 390

Query: 348 FAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTL 407
           FAG V FSV+GFL +++N+ ++ VV    GLAFIVYPE V ++P+S LW++LFF+ML  L
Sbjct: 391 FAGFVTFSVMGFLMNQMNLPIEEVVRSETGLAFIVYPEAVVQMPLSNLWAVLFFLMLFIL 450

Query: 408 GLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMY 459
           GL SQFA ++ ++ AI+D  P+ R  +  V+ +V VF Y      T + G Y
Sbjct: 451 GLGSQFAGVQAISCAIMDVRPDLRPHESRVI-LVGVFIYQMYTYRTASFGDY 501



 Score = 40.3 bits (90), Expect = 0.15
 Identities = 20/80 (25%), Positives = 35/80 (43%), Gaps = 7/80 (8%)

Query: 524 LVFILVFNWIEYKPASYGHYVYPMWADAVGWTXXXXXXXXXXXXXXDQICSGPDDLTIME 583
           LV + ++    Y+ AS+G Y +P+WAD +G                  +  GP D +++ 
Sbjct: 482 LVGVFIYQMYTYRTASFGDYKFPVWADVIGILIGLSTLAPMPIFFCYHLWRGPRDWSLL- 540

Query: 584 KARVLARPTEEWGQAGSTAT 603
                 +P+  WG A   +T
Sbjct: 541 ------KPSSSWGPAKKAST 554


>UniRef50_UPI000069E376 Cluster: Orphan sodium- and
           chloride-dependent neurotransmitter transporter NTT4
           (Solute carrier family 6 member 17).; n=4; Xenopus
           tropicalis|Rep: Orphan sodium- and chloride-dependent
           neurotransmitter transporter NTT4 (Solute carrier family
           6 member 17). - Xenopus tropicalis
          Length = 535

 Score =  378 bits (930), Expect = e-103
 Identities = 194/534 (36%), Positives = 292/534 (54%), Gaps = 32/534 (5%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           +R  W  +  +            NVWRFPYLC  NGGGA+++P+ ++L+I G+PL F+EL
Sbjct: 3   DRPAWNNKLQYILAQIGYSVGLGNVWRFPYLCQKNGGGAYMVPYLILLIIIGIPLFFLEL 62

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
           + GQ    G + V+N  CP   G+GY   +V   V LYYN+II W+IFY    F S  Y 
Sbjct: 63  AVGQRIRRGSIGVWNYICPRLGGIGYASCVVCFFVGLYYNVIIGWSIFYF---FQSFQYP 119

Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPA 204
           LPW  C                    +NG+   +  +       H +  +     +    
Sbjct: 120 LPWNECPT-----------------VKNGSAIYQSSWTNICFCIHTVLVVEAECDKSSAT 162

Query: 205 EEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264
             ++  + L +S+ I E G +   M +CLL AW +V + + KG+QSSGKV+YF++LFPYV
Sbjct: 163 TFFWYREALDISNSISEGGGLNWKMTLCLLVAWTMVCMAMIKGIQSSGKVMYFSSLFPYV 222

Query: 265 VLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSY 324
           VL+    RG+ L G++ GIL  LTP   ++ + QVW +AA Q+FFAL   +GG+I  SSY
Sbjct: 223 VLICFLIRGLFLRGSVDGILHMLTPKVEKMLDPQVWREAATQVFFALGLGFGGVIAFSSY 282

Query: 325 NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAH-ELNVSVDRVVD--QGAGLAFI 381
           NK  NNC  D+ +V+  N  TS  A LV+F+V+GF A+ + N  +    +  QG GLAFI
Sbjct: 283 NKQDNNCQFDAALVSFINFFTSVLATLVVFAVLGFKANFKYNPGLGLYTEAVQGTGLAFI 342

Query: 382 VYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNF----RQKKGWV 437
            + E +T  P SP WS++FF ML+ LGL S    M  + T I+D F        +++  V
Sbjct: 343 AFTEAMTHFPASPFWSVMFFFMLINLGLGSMIGTMSGIITPIIDTFKCLTSWSNEREHTV 402

Query: 438 VFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDI 497
                +  +L GLIF   SG Y++ + D Y+A   + I+ I E I +AW+YG +KF  ++
Sbjct: 403 HCSCCIVAFLLGLIFVQRSGNYFVNMFDDYSATLPLTIVVILENIAVAWVYGTKKFMQEL 462

Query: 498 QRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKP--ASYGHYVYPMWA 549
             M+G +   + Y +S  W+ ++P  +  +L  + I++ P  A+    +YP WA
Sbjct: 463 TEMLGFRPYSY-YFYS--WKYVSPIFMAILLTASVIQFAPFQAAEQFVLYPTWA 513


>UniRef50_Q4S8W1 Cluster: Transporter; n=2; Tetraodontidae|Rep:
           Transporter - Tetraodon nigroviridis (Green puffer)
          Length = 629

 Score =  376 bits (926), Expect = e-103
 Identities = 225/556 (40%), Positives = 317/556 (57%), Gaps = 89/556 (16%)

Query: 60  GGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIV 119
           G   FLIP+ +ML   G+PL  MELS GQY A GP+ V+ K CPL +G+G GM+ VS++V
Sbjct: 84  GQRVFLIPYFIMLFFTGVPLFLMELSLGQYGAAGPIMVW-KCCPLLKGIGIGMLCVSTLV 142

Query: 120 MLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQ 179
            LYYN+IIAWT +Y+  SF S    LPW +C A  +   C          A NG+     
Sbjct: 143 CLYYNVIIAWTFYYLGSSFQS---PLPW-SCDAVANAGLC------GNSTAGNGS----- 187

Query: 180 CFNQSYSVSHNITALAKTALRRPPAEEYFTNQVLGL--SSGIEETGEIRLGMAMCLLAAW 237
              +  S S      + +A+         + +VLG+  S G+ + G +R  +A+CLLAAW
Sbjct: 188 --GRILSPSEIFWNDSSSAVG--------SERVLGVVNSEGLHDPGPVRWRLALCLLAAW 237

Query: 238 VIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANA 297
           +++FLC+ KG++SSGKVVY TA FPY+VLV+L  RG TL G++ G+ FYLTPD+ +L+NA
Sbjct: 238 IVIFLCMLKGIRSSGKVVYVTATFPYLVLVVLIIRGATLEGSLQGVAFYLTPDWGRLSNA 297

Query: 298 QVWGDAAVQIFFALSPAWGGLITLSSYNKFSNN---C----------------------Y 332
           QVW DAA QIF++L    GGL++++SYN+F NN   C                      +
Sbjct: 298 QVWNDAASQIFYSLGIGVGGLLSMASYNRFDNNVIRCVRVLGAAGGSLPWLAFHPGGSPF 357

Query: 333 IDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVD------------------- 373
            D+LI+ + N +TSFFAG  IFS++G +A +  V V  V D                   
Sbjct: 358 RDTLIITIGNCSTSFFAGFAIFSILGHMAWKKGVPVAEVADTGTPETFSQTVSLAVVLHL 417

Query: 374 -------QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDR 426
                   G GLAF+ YPE +  LP S  WSI+FF+ML  LG+D+ F  ME +TTA+LD 
Sbjct: 418 FLGGVFASGPGLAFVAYPEALALLPGSVFWSIMFFLMLFMLGVDTLFGNMEGITTAVLDE 477

Query: 427 FPNFRQK---KGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECIL 483
           FP  R     K   +  +    YL GL+  T+ G+YW  L+D ++ ++ ++IIA+  C+ 
Sbjct: 478 FPQLRLNTVHKSLFLAALCFCFYLMGLLLVTDGGIYWFTLIDSFSTSFGLIIIALFMCLG 537

Query: 484 IAWIYGAEKFCGDIQRMIGR----QSKLWVYLWSAMWRIITPAALVFILVFNWIEY--KP 537
           I++ YG  +FC DI  MI       SK+ +Y + A W + TP  L+FIL + +IE    P
Sbjct: 538 ISFFYGVNQFCQDIIDMICHCPPWCSKVLLY-FKACWIVFTPFLLLFILTYIFIEMYNTP 596

Query: 538 ASYGHYVYPMWADAVG 553
             YG YVYP+W  A+G
Sbjct: 597 LRYGPYVYPLWGKALG 612


>UniRef50_UPI0000D56C9C Cluster: PREDICTED: similar to CG3252-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG3252-PA - Tribolium castaneum
          Length = 619

 Score =  376 bits (924), Expect = e-102
 Identities = 206/542 (38%), Positives = 297/542 (54%), Gaps = 31/542 (5%)

Query: 17  PLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAG 76
           P ++  E ER  W    +F            N+WRFP+  Y NGGGAFLIP+ ++L + G
Sbjct: 25  PENKGDERERAQWGNGLEFLMSCVAMSVGLGNIWRFPFTAYENGGGAFLIPYIIILTLIG 84

Query: 77  LPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTV 136
            PL +ME+S GQ++  G +  +    P  +G+GY  VI +  V  YY  ++A T+FY+  
Sbjct: 85  RPLYYMEMSLGQFSNRGNIRFFKSLSPYLKGVGYAQVIGAGFVATYYCCLMAITLFYLVN 144

Query: 137 SFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAK 196
           SF+     LPW  CK EW            + + ++     +QC +   + S+N T    
Sbjct: 145 SFTG---DLPWSTCKEEWLA----------DLDKEH-----KQCVDAIATTSNN-TKANY 185

Query: 197 TALRRPPAEEYFTNQVLGLSSGIEE-TGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVV 255
           TA+    +E YFT +VL   + I +  G     + +CLLA+W+I FL   KGVQSSGK  
Sbjct: 186 TAVSS--SEVYFTKEVLKEITDISDGIGTPEWRLTLCLLASWIITFLVSVKGVQSSGKAS 243

Query: 256 YFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAW 315
           YF ALFPYV+++ L  R  TL GA  G+ +++  D+++LA A VW  A  Q FF+L+  +
Sbjct: 244 YFLALFPYVIMITLLIRAATLEGAADGMYYFIKTDWAKLAEADVWYAAVTQCFFSLNVGF 303

Query: 316 GGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQ- 374
           G +I  +SYN F +N   D+LIV   +  TS  +G  IF ++G LAH + V+ D V+   
Sbjct: 304 GSIIMFASYNNFEHNINRDALIVTTLDTFTSLLSGATIFGILGNLAHNMGVTPDLVIKSG 363

Query: 375 GAGLAFIVYPEVVTRLPISP-LWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK 433
           G GLAFI YP+ + ++   P L++ILFF ML  LG+ S  AL  TV T + D FP     
Sbjct: 364 GTGLAFISYPDAIAKMEAVPWLFAILFFFMLFVLGVGSLVALHGTVNTVVQDLFPKL--- 420

Query: 434 KGW-VVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEK 492
           K W V    A  G+L GL++ T  G + L L+D YA  + + + A+ E   +AW+YG E 
Sbjct: 421 KSWQVSAYTASGGFLIGLMYVTPGGQFMLNLVDHYAGTFLIFVFAVLEVAAVAWVYGLEN 480

Query: 493 FCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAV 552
           FC D++ M   + K+ VY W   W +ITPA L  I V+  +  +  SY  Y YP    A 
Sbjct: 481 FCLDLEFM--SKKKVSVY-WRMTWGLITPALLFIIFVYFCVRNERLSYASYPYPDGVLAF 537

Query: 553 GW 554
           GW
Sbjct: 538 GW 539


>UniRef50_UPI0000E4659C Cluster: PREDICTED: similar to GABA
           transporter; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to GABA transporter -
           Strongylocentrotus purpuratus
          Length = 691

 Score =  375 bits (923), Expect = e-102
 Identities = 206/534 (38%), Positives = 303/534 (56%), Gaps = 63/534 (11%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           +RG WTG+ DF            NVWRFPYLCY NGGGAFL+P+ + L++AG+P+   E 
Sbjct: 122 KRGKWTGKMDFLLACIGYAIGLGNVWRFPYLCYRNGGGAFLLPYLLTLIVAGIPVFLFET 181

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
           S GQ  +LG + V+ K CPLF+G+GY  V++S  + ++Y ++IAW + Y+  SF+S   +
Sbjct: 182 SLGQLLSLGGLGVW-KICPLFKGVGYAAVVMSFWLNVWYIVVIAWALLYLANSFTS---K 237

Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPA 204
           LPW          HC            N    L    NQ+  +++N T          P 
Sbjct: 238 LPWS---------HC-----------DNDFNTLNCTTNQT--LANNYTT--------DPT 267

Query: 205 EEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264
            E++   VL  S GI + G++R  +A+ LLAAW+I + C+ KGV+ +GKVVYFTAL+PYV
Sbjct: 268 TEFWKQYVLEESDGIHQPGKVRWQLAVTLLAAWIICYFCIWKGVKWTGKVVYFTALYPYV 327

Query: 265 VLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSY 324
           +L++LFFRGVTL GA  GI++Y+ P+FS+L ++ VW DAA QIFF+     G LI L SY
Sbjct: 328 MLIVLFFRGVTLEGAREGIIYYIKPNFSRLTDSGVWIDAATQIFFSYGTGIGSLIALGSY 387

Query: 325 NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYP 384
           NKFSNN Y DS+IVA  N  TSFFAG V+FS +G LAH  N  V  V   G GL F+ YP
Sbjct: 388 NKFSNNVYRDSMIVACVNTGTSFFAGFVVFSTLGHLAHVQNKDVADVATSGPGLTFLAYP 447

Query: 385 EVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQ-KKGWVVFIVAV 443
             + +LP   +W+++FF M+  +GLDSQ  +   +  ++  +  + R+ +K ++    A+
Sbjct: 448 AAIAQLPFPAVWAVMFFSMIFMVGLDSQVTMTTEIYNSLSSKPMSLRKPRKLFISNYFAL 507

Query: 444 FGYLGGLIFTTNSGMYWLQLMDKYAANW-SVLIIAIGECILIAWIYGAEK--FCGDIQRM 500
           F  L  L   +  G+Y  +L++ Y+++  S+L +   + I ++W YG     F G  Q  
Sbjct: 508 FFPL-SLALPSQGGIYVFELLNTYSSSGISLLFLTFFQTIGVSWFYGNTPGYFGGASQHY 566

Query: 501 IGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGW 554
            G                        + +F+ ++YK   Y  Y YP+W + +GW
Sbjct: 567 SG------------------------VFLFSLVKYKRVEYEDYTYPVWGEVIGW 596


>UniRef50_UPI0000E4A90B Cluster: PREDICTED: similar to
           ENSANGP00000013630, partial; n=6; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to
           ENSANGP00000013630, partial - Strongylocentrotus
           purpuratus
          Length = 597

 Score =  373 bits (917), Expect = e-101
 Identities = 196/550 (35%), Positives = 300/550 (54%), Gaps = 33/550 (6%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           +R NW GRFDF            N+WRFPYLCY NGGGAFL+P+  +L+   +PL+ +E 
Sbjct: 53  KRENWGGRFDFAISCLGYAVGLSNIWRFPYLCYKNGGGAFLVPYCTLLLFVCIPLIVLEF 112

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
           + GQY++     V+    P+ RG+ Y  ++   +   YY ++I++ ++Y    F+S+   
Sbjct: 113 AIGQYSSSNFAKVWRAL-PIMRGIWYCQMLSYIVGNGYYGVVISYAVYYF---FASLTSH 168

Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLR-QCFNQSYS-----VSHNITALAKTA 198
           LPW  C  +W+T +C   E  D+C  Q+G       C N +         +N+T    T 
Sbjct: 169 LPWVGCGHKWNTLYCS--ELFDDCLNQDGIIISNGSCANVTLLSDEELAGYNVTVFNDTF 226

Query: 199 L------------RRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCK 246
           L            R  P+EEY+T      SS IE+ G +   +A+C L  WV++FL + K
Sbjct: 227 LDFSNYTDPIKNMRVLPSEEYWTE-----SSSIEKPGGVVWQLALCNLFVWVVIFLIIAK 281

Query: 247 GVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQ 306
           G+++SGKVVYFTALFPYV++  L  R +TL G + GI +++ P +S++ +   W DAA Q
Sbjct: 282 GIKTSGKVVYFTALFPYVMMTALLIRALTLDGYMDGIRYFVKPTWSKIVHPLPWKDAAQQ 341

Query: 307 IFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNV 366
           +FF+     G L T++S+N F N    D+LI+A+ N  TS + G  +F+++G++A ++ V
Sbjct: 342 VFFSSGSGGGSLGTMASFNTFHNTFVNDALIMAIGNSLTSLYCGFAVFAILGYMAKQIGV 401

Query: 367 SVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDR 426
            V  VV  G GL F+V P  + + P   +WS LFF M+  L LDSQF  +E + T ILD 
Sbjct: 402 PVQEVVKGGFGLVFVVCPAALAKFPGRSVWSALFFGMIFLLALDSQFVCIEAMVTVILDA 461

Query: 427 FPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAW 486
            P  R+ +  V   +    YL    + TN+G YW+ L+D Y A W  +I  I   I   W
Sbjct: 462 MPRLRRWRVLVCAFLCFGTYLTTFSYVTNAGPYWVALLDNYYAGWISMITGIAIPISFTW 521

Query: 487 IYGAEKFCGDIQRMIGRQS-KLWV-YLWSAMWRIITPAALVFILVFNWIEYKPASYGHYV 544
           +YG ++   D++ M+G ++   W  Y W   W  +TP  LV + VF  +   P     + 
Sbjct: 522 VYGFDRLKNDMRAMLGNKTVDHWTFYYWKISWMFLTPGILV-VSVFKHLTTFPGGIKEF- 579

Query: 545 YPMWADAVGW 554
           + +  DA+GW
Sbjct: 580 HLVSDDALGW 589


>UniRef50_UPI0000EB09CC Cluster: UPI0000EB09CC related cluster; n=1;
           Canis lupus familiaris|Rep: UPI0000EB09CC UniRef100
           entry - Canis familiaris
          Length = 516

 Score =  371 bits (913), Expect = e-101
 Identities = 199/539 (36%), Positives = 299/539 (55%), Gaps = 35/539 (6%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           ER  W  +  +            N+WRFPYLC   GGGAFLIP+ + LV  G+PL ++EL
Sbjct: 1   ERPKWDNKLQYLLSCIGFAVGLGNIWRFPYLCQTYGGGAFLIPYLIALVFEGIPLFYVEL 60

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
           + GQ    G + V+    P   G+G G V VS +V LYYN ++ W ++Y   SF S    
Sbjct: 61  AIGQRLRRGSIGVWTAISPYLGGVGLGCVTVSFLVSLYYNTVLTWVLWYFLNSFQS---P 117

Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPA 204
           LPW +C  + +         A       G  +  +C   S +VS+               
Sbjct: 118 LPWSSCPLDVNRTGIGPTCCAWHSGGIPGPGFEAEC-QASSTVSY--------------- 161

Query: 205 EEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264
             ++  Q L +++ I ++G I+  +  CL A+W +V+LC+ +G++S+GK +YFTALFPY+
Sbjct: 162 --FWYRQTLNITADISDSGSIQGRLLACLAASWAVVYLCVIRGIESTGKAIYFTALFPYL 219

Query: 265 VLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSY 324
           VL I   RG+TLPGA+ G+++  TPD   L N +VW DAA QIFF+LS A+GG I  +SY
Sbjct: 220 VLTIFLIRGLTLPGAVEGLIYLFTPDVQILQNPRVWLDAATQIFFSLSLAFGGHIAFASY 279

Query: 325 NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGF-LAHELNVSVDRVVDQGAGLAFIVY 383
           N   NNC  D++ +A+ N  TS +A + +FSV+GF  A++    +DR    G GLAFI++
Sbjct: 280 NPPRNNCEKDAVTIALVNSMTSLYASIAVFSVLGFKAANDHGRCLDRSA-SGTGLAFIIF 338

Query: 384 PEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQ-KKGWVVFIVA 442
            E +  +P +P W++LFF ML TLGL S F  ME++ T +LD     R   K  +  +  
Sbjct: 339 TEAILHMPGAPGWAVLFFGMLFTLGLSSMFGNMESIITPLLDMGLTHRSIPKEVLTGLAC 398

Query: 443 VFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIG 502
           +  +L  + FT  SG YWL++ D YAA  +++I A  E I +A++YG ++F  DI  M G
Sbjct: 399 LLCFLSAICFTLQSGNYWLEVFDNYAAPLNLIIFAFLEVIGVAYVYGLQRFSDDIVCMTG 458

Query: 503 RQSKLWVYLWSAMWRIITPAAL--VFILVFNWIEYKPASY----GHYVYPM--WADAVG 553
           R+  L+   W   W++++P  L  +F+     + + P SY      YV P+  W   +G
Sbjct: 459 RRPSLY---WRVTWKVVSPLLLLTIFVAYIAVLVWTPLSYRAWNTQYVGPLGEWGATLG 514


>UniRef50_UPI0000DB6B93 Cluster: PREDICTED: similar to CG3252-PA;
           n=3; Apis mellifera|Rep: PREDICTED: similar to CG3252-PA
           - Apis mellifera
          Length = 625

 Score =  370 bits (911), Expect = e-101
 Identities = 204/596 (34%), Positives = 307/596 (51%), Gaps = 37/596 (6%)

Query: 8   KGDEEKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIP 67
           +G+ +K+K   +++I P R  W G   F            NVWRFP+  Y NGGGAFLIP
Sbjct: 29  RGNNQKTKEEDAKDI-PSRAEWGGGLQFLMACIATSVGLGNVWRFPFTAYENGGGAFLIP 87

Query: 68  FTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLII 127
           + ++L+  G P  F+E   GQ+        +    P  +GLGYG    +  V+ YY  ++
Sbjct: 88  YIIVLIFVGKPFYFLEALLGQFTNRSCAKTWG-MVPAMKGLGYGQAFAAFCVVTYYCSLM 146

Query: 128 AWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSV 187
             T++Y+  SF S   +LPW  C+ EW     Y  +   +    N +  L   +N ++  
Sbjct: 147 GLTLYYLVASFQS---ELPWSYCREEWKD---YCVDTVSKDNNLNRSASLLTIYNDTF-- 198

Query: 188 SHNITALAKTALRRPPAEEYFTNQVLGLSSGIEE-TGEIRLGMAMCLLAAWVIVFLCLCK 246
                        R  AE YF   VL     IE   G     + +CL  +W  +F  LC+
Sbjct: 199 -------------RSSAELYFRKIVLNEYESIENGIGTPSWQLTICLFVSWATIFCVLCR 245

Query: 247 GVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQ 306
           G++S+GK VYF A+FPYV++  L  R VTL GA+ GILF +TPD+ +L    VW  A  Q
Sbjct: 246 GIKSTGKAVYFLAIFPYVIMTGLLIRSVTLEGAVNGILFLVTPDWDKLWQPNVWYAAITQ 305

Query: 307 IFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHEL-N 365
            FF+LS  +G ++T SSYN F +    D LIV   +  TS  AG  IF ++G LAHEL N
Sbjct: 306 CFFSLSVCFGPILTYSSYNNFQHGVSRDVLIVTTLDTFTSLIAGCTIFGILGNLAHELGN 365

Query: 366 VSVDRVVDQGAGLAFIVYPEVVTRLPISP-LWSILFFVMLLTLGLDSQFALMETVTTAIL 424
             + +VV  G GLAFI YPE +++    P L+++LFF+M+  LG+ S  AL   +   + 
Sbjct: 366 ADISKVVRGGTGLAFISYPEALSQFNFVPQLFAVLFFIMMFVLGVGSAVALCGAIFCILC 425

Query: 425 DRFPNFRQKKGW-VVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECIL 483
           D FPN    K W +VFIV+ FG+L  L++ T  G +++ L+D Y   +  +I+ + E I 
Sbjct: 426 DHFPN---TKHWQLVFIVSFFGFLVSLVYVTPGGQWFVTLVDYYGGTFVAIIVGVLEMIT 482

Query: 484 IAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHY 543
           + WIYG   F  D++ M+G +     + W   W  ITP  ++ IL++  + Y+  +Y + 
Sbjct: 483 VFWIYGLSNFINDVEFMLGGRPS---FYWRLCWAFITPILMIVILIYTVVTYESPTYDNM 539

Query: 544 VYPMWADA--VGWTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEE-WG 596
            +P +A    +GW                ++       +I+E  +   RP+EE WG
Sbjct: 540 PFPDYAYGWFIGWFLLALALFVIAGCILQKMIQLRSS-SIIETVKAAFRPSEEKWG 594


>UniRef50_UPI0000DB6B91 Cluster: PREDICTED: similar to CG3252-PA;
           n=1; Apis mellifera|Rep: PREDICTED: similar to CG3252-PA
           - Apis mellifera
          Length = 609

 Score =  361 bits (889), Expect = 2e-98
 Identities = 191/549 (34%), Positives = 298/549 (54%), Gaps = 29/549 (5%)

Query: 8   KGDEEKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIP 67
           K  EE     +  EI+ ER  W    +F            N+WRFP+  Y NGGG FLIP
Sbjct: 8   KSCEESRCVEIGREIK-ERSKWNNEIEFLMSCIAISIGFGNIWRFPFTAYENGGGVFLIP 66

Query: 68  FTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLII 127
           + ++L + G P+ +ME+  GQ+++   + V+N   P F G+G+     ++ +M YY+ ++
Sbjct: 67  YIIVLFLVGKPIYYMEIILGQFSSSSSINVWN-VSPGFSGIGWSQFYCNTALMTYYSSLM 125

Query: 128 AWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSV 187
           A T+F++  SFS+   +LPW  C+ EW   +C       +    N T ++ Q  N+    
Sbjct: 126 ALTLFFLIASFSA---ELPWAKCREEW-LDYCIDSSHQIDNNTSNITSFV-QLLNEKE-- 178

Query: 188 SHNITALAKTALRRPPAEEYFTNQVLGLSSGIEE-TGEIRLGMAMCLLAAWVIVFLCLCK 246
                       RR  AE YF   VL     IE+  G     + +CLL +W+ V L   +
Sbjct: 179 ------------RRSSAELYFLKVVLEEKDSIEDGIGLPSWKLTLCLLVSWISVILITSQ 226

Query: 247 GVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQ 306
           GV+SSGK  YF A+FPY++L  L  R VTL GA TGILF++TP++S+L    VW  A  Q
Sbjct: 227 GVKSSGKASYFLAIFPYIILFSLLIRAVTLDGAATGILFFVTPEWSKLFEPSVWYAAVTQ 286

Query: 307 IFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNV 366
            FF+LS  +G ++T SS+N F +N Y D LIV   +  TSF AG  IF ++G LAH++ +
Sbjct: 287 CFFSLSVCFGPILTYSSHNDFKHNLYRDVLIVTTLDTLTSFIAGCTIFGILGNLAHKMGL 346

Query: 367 -SVDRVVDQGAGLAFIVYPEVVTRLPISP-LWSILFFVMLLTLGLDSQFALMETVTTAIL 424
             +++VV  G GLAFI YP+ + +  + P L+++LFFVM+  LG+ S   ++  +  ++ 
Sbjct: 347 EDINKVVKSGVGLAFISYPDAIAKFNVVPQLFAVLFFVMMFVLGVGSIVGMVSGLAHSLK 406

Query: 425 DRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILI 484
           ++ PN +  K  +V  +    +    I+ T  G + L L+D Y  ++ V  +A  E   I
Sbjct: 407 EKLPNVQMWK--IVLCICSISFAVSTIYVTPGGQFLLSLVDYYGTSFVVFFLASFEITAI 464

Query: 485 AWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYV 544
            W+YG E F  D++ M+ R++  +   W   W ++TP  L+FI  + +   +P +YG   
Sbjct: 465 MWVYGIENFLNDVEFMLSRRTGSY---WRICWFLVTPFILLFIFFYTFATLQPLTYGEKE 521

Query: 545 YPMWADAVG 553
           YP+ A A G
Sbjct: 522 YPISAHAAG 530


>UniRef50_A1Z8V9 Cluster: Transporter; n=3; Drosophila
           melanogaster|Rep: Transporter - Drosophila melanogaster
           (Fruit fly)
          Length = 629

 Score =  359 bits (884), Expect = 9e-98
 Identities = 201/592 (33%), Positives = 304/592 (51%), Gaps = 38/592 (6%)

Query: 8   KGDEEKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIP 67
           +G+E         E   +R  W+   +F            NVWRFP++   NGGGAFLIP
Sbjct: 39  EGEELTINCEAESESSGQRDQWSRGVEFLFSCIALSVGLGNVWRFPFIALENGGGAFLIP 98

Query: 68  FTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLII 127
           + ++L++ G P+ ++E+  GQ+++ G +  ++   P+ RG+ YG V  +++   YY  I+
Sbjct: 99  YVIVLLLIGRPVYYLEVIIGQFSSRGCIRAFD-MAPIMRGIAYGQVYSTALATTYYACIM 157

Query: 128 AWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSV 187
           A TI Y+  SFS +   LPW  C  EW  K C     A    A N +  ++        V
Sbjct: 158 ALTIRYLVASFSEV---LPWTYCLVEWG-KSCV----ATGATAANDSSIVQ-------GV 202

Query: 188 SHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKG 247
           S       +T LR P   E   +  LG  S           + +CLLA WVI+   L KG
Sbjct: 203 SSAELFFTQTVLREP---ESLDDNGLGTPSW---------DLVLCLLATWVIIGTILSKG 250

Query: 248 VQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQI 307
           ++SSGK  YF ALFPYV++++L  R VTLPGA  GI+++L P +SQL N  VW  A  Q+
Sbjct: 251 IRSSGKASYFLALFPYVIMIVLLIRAVTLPGAWQGIVYFLKPQWSQLLNPHVWYAAITQM 310

Query: 308 FFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNV- 366
           FF+L+  +G L+  +S+N F+ N + D +I+   +  TS  AG +IF ++G LA E N  
Sbjct: 311 FFSLAICFGTLVMYASFNDFNKNVHKDVIIITTIDSLTSILAGCIIFGILGNLAFETNTK 370

Query: 367 SVDRVVDQGAGLAFIVYPEVVTRLPISP-LWSILFFVMLLTLGLDSQFALMETVTTAILD 425
            + +VV  GAGLAFI YPE + +    P L+++LFF MLL LG+ S   +   V   + D
Sbjct: 371 DISQVVKGGAGLAFISYPEAIAKFKYLPQLFAVLFFFMLLVLGIGSNIGMASAVVNVVKD 430

Query: 426 RFPNFRQKKGWVVFIVA-VFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILI 484
           RF +      W++ + A + G+L GL++ T  G + L L+D Y   +  L++AI E + +
Sbjct: 431 RFTHLPH---WLLAVSASIIGFLCGLVYMTPGGQFVLNLVDFYGCTFIALVLAIAELLAV 487

Query: 485 AWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYV 544
            WIYG ++ C DI+ M+  ++    + W   W I+ P  +  +LV+    Y+P +Y    
Sbjct: 488 GWIYGVKRICSDIEFMLNVKTS---FYWRICWAIVAPGLMFLVLVYMLFSYEPLTYRGVQ 544

Query: 545 YPMWADAVGWTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWG 596
           YP      GW                 I   P   T   K  +  +PT  WG
Sbjct: 545 YPPVYYMAGWIIWGLGVLQLPFWALVTIYQQPGK-TFGSKFGLAMQPTANWG 595


>UniRef50_Q4T2D0 Cluster: Transporter; n=3; Euteleostomi|Rep:
           Transporter - Tetraodon nigroviridis (Green puffer)
          Length = 563

 Score =  359 bits (883), Expect = 1e-97
 Identities = 180/429 (41%), Positives = 258/429 (60%), Gaps = 32/429 (7%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           R  W+ + DF            NVWRFPY+CY NGGGAFL+P+ +M +  G+PL +MEL+
Sbjct: 1   RETWSKKVDFLLSVIGYAVDLGNVWRFPYICYQNGGGAFLLPYLLMALFGGVPLFYMELA 60

Query: 86  FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQL 145
            GQ+   G ++++   CP+F+G+G+ + I++  +  YYN I+AW ++Y+  SF S    L
Sbjct: 61  LGQFHHSGCISIWKHVCPIFKGIGFAICIIALYIAFYYNTIMAWALYYLLSSFQST---L 117

Query: 146 PWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAE 205
           PW  C   W+T +C  Y   D               N S+S S              PAE
Sbjct: 118 PWSTCTNSWNTANCNHYMSTDH--------------NVSWSNSST-----------SPAE 152

Query: 206 EYFTNQVLGL--SSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPY 263
           E++  QVL +  S G+ + G I   +A+CLL  + IVF  + KGV++SGKVV+ TA FPY
Sbjct: 153 EFYVRQVLQVHRSPGLHQLGSISWQLALCLLFIFTIVFFSIWKGVKTSGKVVWVTATFPY 212

Query: 264 VVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSS 323
           +VL++L  RG TLPGA  G++FYL PD+ +L +  VW DAA QIFF+L P +G L+  +S
Sbjct: 213 LVLLVLLIRGATLPGAWRGVVFYLKPDWEKLLSTTVWIDAAAQIFFSLGPGFGVLLAFAS 272

Query: 324 YNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVV-DQGAGLAFIV 382
           YN F NNCY D+LI +  N  TSF +G VIF+V+G++A      VD V  D G  L FI+
Sbjct: 273 YNPFHNNCYKDALITSSVNCLTSFLSGFVIFTVLGYMAEMRQQDVDAVAKDAGPSLLFII 332

Query: 383 YPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPN-FRQKKGWVVFIV 441
           Y E +  +P +  +SI+FF+M++ LGLDS FA +E V TA+LD +P+   Q++  +VF +
Sbjct: 333 YAEAIANMPAATFFSIIFFLMIIMLGLDSTFAGLEGVITAMLDEYPHVLVQRREKLVFGL 392

Query: 442 AVFGYLGGL 450
               YLG L
Sbjct: 393 VCVCYLGAL 401



 Score = 64.9 bits (151), Expect = 6e-09
 Identities = 31/109 (28%), Positives = 57/109 (52%), Gaps = 5/109 (4%)

Query: 447 LGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSK 506
           LG        G + ++L ++YA   +V+ + + E I ++W YG ++FC D+Q M+G    
Sbjct: 431 LGWCRLLPQGGAFVVKLFEEYATGPAVITVVLLEVIAVSWFYGTKRFCNDVQVMLGFYPG 490

Query: 507 LWVYLWSAMWRIITPAALVFILVFNWIEYKP-ASYGHYVYPMWADAVGW 554
           ++   W   W  I P  L+FI++ +++ + P      Y YP W   +G+
Sbjct: 491 IF---WRVCWVAICPCFLMFIII-SFLAFPPEVRLFSYHYPPWTTVLGY 535


>UniRef50_A1L1P6 Cluster: Transporter; n=3; Danio rerio|Rep:
           Transporter - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 537

 Score =  357 bits (878), Expect = 5e-97
 Identities = 183/395 (46%), Positives = 256/395 (64%), Gaps = 17/395 (4%)

Query: 175 YYLRQCFNQ----SYSVSHNITALA-KTALRRPPAEEYFTNQVLGL--SSGIEETGEIRL 227
           YYL   F      S     NI   A KT   + P+E ++  +VLG+  S+G+ + G +R 
Sbjct: 61  YYLGSSFQSPLPWSCDALQNIALCANKTNSTQSPSEVFWNEKVLGVVHSTGLSDPGPVRW 120

Query: 228 GMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYL 287
            +A+CLLAAW+I+FLC+ KG+ SSGKVVY TA FPY VL++L  RG TL G++ G+ FYL
Sbjct: 121 PLALCLLAAWIIIFLCMLKGIHSSGKVVYLTATFPYFVLLVLIIRGATLEGSLDGVAFYL 180

Query: 288 TPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSF 347
           TP + QLA+AQVW DAA QIF++L    GGL++++SYNKF NN   D++I+ + N +TSF
Sbjct: 181 TPKWDQLADAQVWNDAASQIFYSLGIGVGGLLSMASYNKFDNNVIRDTIIITIGNCSTSF 240

Query: 348 FAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTL 407
           FAG  IFS++G +A +  V VD+V D G GLAF+ YPE +  LP S  WSILFF+ML  L
Sbjct: 241 FAGFAIFSILGHMAFKKGVPVDKVADSGPGLAFVAYPEALALLPGSVFWSILFFLMLFML 300

Query: 408 GLDSQFALMETVTTAILDRFPNFRQK-KGWVVFI-VAVFG-YLGGLIFTTNSGMYWLQLM 464
           G+D+ F  ME + TA+LD FP  R   K   +F+ V  F  YL GL+  T+ G+YW  L+
Sbjct: 301 GVDTLFGNMEGICTAVLDEFPQLRSNLKHKTLFLAVLCFSFYLMGLLLITDGGIYWFTLI 360

Query: 465 DKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGR----QSKLWVYLWSAMWRIIT 520
           D ++ ++ ++II +  CI I++ YG  +FC DI  MI R     +K+ +Y + A W + T
Sbjct: 361 DSFSTSFGLIIITLFMCIGISFFYGVNQFCQDIVDMICRCPPWCTKMLLY-FKACWVVFT 419

Query: 521 PAALVFILVFNWIE-YKPA-SYGHYVYPMWADAVG 553
           P  L FIL + +IE Y+ +  YG YVYP+W  A+G
Sbjct: 420 PFLLTFILTYIFIEMYRTSLRYGSYVYPIWGKALG 454



 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 45/82 (54%), Positives = 57/82 (69%), Gaps = 5/82 (6%)

Query: 71  MLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWT 130
           ML   G+PL  MELS GQY A GP+ V+ K CPL +G+G GM+ VS++V LYYN+IIAWT
Sbjct: 1   MLFFTGMPLFLMELSLGQYGAAGPITVW-KCCPLLKGIGIGMLCVSTLVCLYYNVIIAWT 59

Query: 131 IFYMTVSFSSIFYQLPWQNCKA 152
            +Y+  SF S    LPW +C A
Sbjct: 60  FYYLGSSFQS---PLPW-SCDA 77


>UniRef50_Q17EZ6 Cluster: Sodium/shloride dependent amino acid
           transporter; n=5; Culicidae|Rep: Sodium/shloride
           dependent amino acid transporter - Aedes aegypti
           (Yellowfever mosquito)
          Length = 637

 Score =  356 bits (875), Expect = 1e-96
 Identities = 199/541 (36%), Positives = 299/541 (55%), Gaps = 45/541 (8%)

Query: 18  LSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGL 77
           ++++  P R  W    +F            NVW+FPY    NGGGAFLIP+ V+L + G 
Sbjct: 57  VAKKPSPVRDKWGKDVEFMLSCIAYSVGFGNVWKFPYTALKNGGGAFLIPYLVVLFLVGR 116

Query: 78  PLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVS 137
           P+ ++E+  GQ+++ G V +Y+   P  RG+G G  I   IVM YY  I+A T  Y+  S
Sbjct: 117 PIYYLEMVMGQFSSRGVVKIYD-LSPAMRGIGVGQSIAMFIVMTYYTPILAITFRYLVAS 175

Query: 138 FSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKT 197
           FS++   LPW  C   W   +C   +            ++ Q  N       N +   K 
Sbjct: 176 FSAV---LPWAKCDPSWP--NCVDSD------------FVGQIVN-------NASIKPKA 211

Query: 198 ALRRPPAEEYFTNQVLGLSSGIEE-TGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVY 256
           +     AE YF N V+  ++ + E  G     + +CLL AW+ V   L KG++SSGK  Y
Sbjct: 212 S-----AELYFQNSVMHQNASLYEGLGLPDWKLVLCLLFAWLCVATILIKGIKSSGKASY 266

Query: 257 FTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWG 316
           F A+FPYV+++ILF    TL GA  GI+F+LTP + QL N  VW +A  Q FF+LS  +G
Sbjct: 267 FLAIFPYVIILILFVHACTLDGAFNGIMFFLTPQWDQLLNVTVWYEAVTQCFFSLSVCFG 326

Query: 317 GLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHEL-NVSVDRVVDQG 375
           G+I  +S+N FSNN Y D++I++  +  TS  AG ++F VIG LA+      +  VV  G
Sbjct: 327 GIIAYASFNNFSNNVYKDAIIISWLDTFTSIIAGCIVFGVIGNLAYVTEQQDIQAVVKSG 386

Query: 376 AGLAFIVYPEVVTRLPISP-LWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKK 434
           AGL F+ YP+ + +    P L+S LFF+ML  +GL S   +  ++ TAI D+ P   + K
Sbjct: 387 AGLTFMTYPDAIAKFDWLPQLFSALFFLMLFIVGLGSNLGVTTSIVTAIKDQCP---ELK 443

Query: 435 GW-VVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKF 493
            W VV  VAV G+  G+++ T  GM+ L ++D Y A +  L  A+ E   +AWIYG ++ 
Sbjct: 444 NWQVVSAVAVAGFSFGIVYLTPGGMHLLDILDYYGAKYVTLTFAVLELATLAWIYGVDRI 503

Query: 494 CGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVG 553
           C DI+ M+G ++ L+   W   W ++TP   V IL+ ++I+Y+      +V P+  + +G
Sbjct: 504 CRDIKFMLGIETSLF---WRICWGVVTPLVTVAILLLSFIDYEA-----FVVPVGYNVLG 555

Query: 554 W 554
           W
Sbjct: 556 W 556


>UniRef50_Q4T523 Cluster: Transporter; n=6; Tetraodontidae|Rep:
           Transporter - Tetraodon nigroviridis (Green puffer)
          Length = 535

 Score =  351 bits (864), Expect = 3e-95
 Identities = 189/539 (35%), Positives = 290/539 (53%), Gaps = 34/539 (6%)

Query: 62  GAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVML 121
           G FL+P+    V+ GLPL  +E   GQY   G V  + K CPL  G GY  ++V  +   
Sbjct: 1   GVFLLPYCFFAVLCGLPLFLLESVIGQYTQEGAVTCWKKLCPLSEGTGY-FILVIQLYSR 59

Query: 122 YYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCF 181
            Y +++AW + Y+   F      LPW  C + W+T  C      +    Q+G   L    
Sbjct: 60  LYTIVLAWALLYIIYCFRD---PLPWATCSSPWNTDRCVDLSSVNLTAGQSGNVTLNV-- 114

Query: 182 NQSYSVSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVF 241
                 S N+T  + T        E++  QVL +S GIEE G+++  + +CLLA W+  +
Sbjct: 115 -----TSGNLTTSSVT--------EFWERQVLSMSGGIEELGKVQWELLLCLLACWMSCY 161

Query: 242 LCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWG 301
            C+ KGV+S+GKVVYFTA+FPYV+LVIL  RG+TLPGA+ G+++YL PD S+LA+ QVW 
Sbjct: 162 FCIWKGVRSTGKVVYFTAIFPYVMLVILLIRGLTLPGALQGVVYYLYPDVSRLADLQVWM 221

Query: 302 DAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLA 361
           DA  Q+ F+   + G LIT  SYNK +NNC  DSL + + N  TSF AG  +FSV+GF+A
Sbjct: 222 DACSQVLFSYGVSSGTLITFGSYNKLNNNCCRDSLWLCLLNSCTSFVAGFTVFSVLGFMA 281

Query: 362 HELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTT 421
            +  V +  VVD    + F+   +   R+P   LW+ +  +  L +    QF+ +ET+T 
Sbjct: 282 QQQGVPISNVVD-SVQMCFVDLEKAFDRVPWRVLWTRVSELDPLLMCATCQFSGLETITA 340

Query: 422 AILDRFPNFRQKKGW-----VVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLII 476
           A++D FP  + ++ W     +V   +VF +L  ++  T  G+Y  QL+D YAAN S ++ 
Sbjct: 341 AVIDLFPR-KMRRPWRREIFLVIFCSVF-FLVQILLVTEGGVYLFQLIDHYAANGSCIMF 398

Query: 477 -AIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEY 535
            ++  C+++ W +GA+K C  ++ + G +   W + +   WR  TP       + + I Y
Sbjct: 399 GSVIHCVVVGWAFGADKICDAVEDITGHRP--WAF-YKLCWRYFTPLICTVCFICSLINY 455

Query: 536 KP-ASYGHYVYPMWADAVGWTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTE 593
           +   S   YVYP WA ++GW                ++C      T+ ++  VL  P +
Sbjct: 456 QSLISSKGYVYPDWAYSLGWAMAWSSIVTVPIYAIVKLCLTKG--TLQQRLMVLWHPDD 512


>UniRef50_Q9VSV2 Cluster: Transporter; n=3; Sophophora|Rep:
           Transporter - Drosophila melanogaster (Fruit fly)
          Length = 629

 Score =  350 bits (860), Expect = 8e-95
 Identities = 191/542 (35%), Positives = 303/542 (55%), Gaps = 40/542 (7%)

Query: 19  SEEIEPER---GNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIA 75
           S E+ P+R    NW    +F            NVWRFP+    NGGGAFLIP+ V+L + 
Sbjct: 41  SSELSPDRKARDNWGSSLEFLMSCIALSVGLGNVWRFPFTALENGGGAFLIPYLVVLFVV 100

Query: 76  GLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMT 135
           G P+ +ME+  GQ+++ G V V++ F PL RG+GY  ++   ++  YY  ++A T+ Y  
Sbjct: 101 GKPIYYMEMLLGQFSSRGIVQVFD-FAPLMRGVGYAQLLALGVLATYYASVMALTLRYFF 159

Query: 136 VSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALA 195
            SF+S   +LPW  C+ EW           D C + +G   L+   ++++S S  +  L 
Sbjct: 160 DSFAS---ELPWSFCREEW----------GDGCVSASGGQPLQGQLSRNFSSSTQL-YLQ 205

Query: 196 KTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVV 255
           +  L    + E    + +G  SG          +A+ L  +W+ V L + +GV+SSGK  
Sbjct: 206 RIVLNETDSLE----EGIGYPSG---------SLALMLGISWLTVTLIIIRGVKSSGKAA 252

Query: 256 YFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAW 315
           Y  ALFPYVV+ IL  R +TLPGA  G++++LTP + +L   QVW +A  Q+FF+L+  +
Sbjct: 253 YVLALFPYVVMFILLVRALTLPGAYDGVMYFLTPQWEKLLEPQVWYNAVTQVFFSLAVCF 312

Query: 316 GGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNV-SVDRVVDQ 374
           G +I  SSYN+F +N Y D+ IV   +  TS  +G++IF ++G LAHE     +  VV  
Sbjct: 313 GVIIMYSSYNRFGHNVYRDANIVTTLDTFTSLLSGVIIFGILGNLAHESGTKDIASVVKA 372

Query: 375 GAGLAFIVYPEVVTRLPISP-LWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK 433
           G GLAFI YP+ + +  + P ++S+LFF ML  LG+ S   ++  + T + D+F N    
Sbjct: 373 GPGLAFISYPDAIAKFKMFPQVFSLLFFAMLFMLGVGSNVGMVSCIMTVLKDQFVNV--- 429

Query: 434 KGWVVFI-VAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEK 492
           K W++ + ++V G+L GLI+ T  G + + LMD +   +  L+ AI E I + WIYG ++
Sbjct: 430 KLWIIVVSLSVIGFLVGLIYITPGGQHIITLMDFHGVTFVSLVSAIFELIAVGWIYGTKR 489

Query: 493 FCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAV 552
            C D + M+  ++  +   +   W I+TP  ++ ILV++ +  +P SY    +P+    V
Sbjct: 490 LCQDAEYMLNIKTSNY---YRICWSIVTPLVMLVILVYSLLTMRPLSYNGQEFPLVYRVV 546

Query: 553 GW 554
           GW
Sbjct: 547 GW 548


>UniRef50_Q4SBR4 Cluster: Transporter; n=8; Euteleostomi|Rep:
           Transporter - Tetraodon nigroviridis (Green puffer)
          Length = 672

 Score =  347 bits (854), Expect = 4e-94
 Identities = 182/436 (41%), Positives = 256/436 (58%), Gaps = 18/436 (4%)

Query: 127 IAWTIFYMTVSFS-SIF--YQLPWQNCKAEWSTKHCYS-YEEADECEAQNGTYYLRQCFN 182
           I W+   M +  + S+F   +LPWQ+C   W+T+ C+S Y   D       T  L     
Sbjct: 189 ILWSFDLMPLGVTRSLFCVQELPWQSCDNPWNTEKCFSNYSLTD-------TTNLTSAVT 241

Query: 183 QSYSVSHNITALAKTA--LRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIV 240
           + +    +  A  K    LR        T  +  LSSG+EE GE+R  +   L  AWV+V
Sbjct: 242 EFWEYGRHECAERKVGRMLRMLTCGVSSTRNMHQLSSGLEEPGELRWPLVGTLALAWVLV 301

Query: 241 FLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVW 300
           +  + KGV+ +GKVVYF+A +PY +L ILFFRGVTLPGAI GILFY+TPDF++L  ++VW
Sbjct: 302 YFSIWKGVEWTGKVVYFSATYPYFMLFILFFRGVTLPGAIDGILFYITPDFNKLIRSEVW 361

Query: 301 GDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFL 360
            DAA QIFF+     G LI L SYN ++N+ Y DS+IV   N  TS FAG VIFS++GF+
Sbjct: 362 LDAATQIFFSYGLGLGSLIALGSYNTYNNDVYKDSIIVCCINSCTSMFAGFVIFSIVGFM 421

Query: 361 AHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVT 420
           ++     V  +   G GLAF+ YP+ VT+LP+S LW+ILFF ML+ LGLDSQF  +E   
Sbjct: 422 SYITKKPVQELAASGPGLAFLAYPQAVTQLPMSSLWAILFFSMLMMLGLDSQFCTVEGFI 481

Query: 421 TAILDRFP-NFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAAN-WSVLIIAI 478
           TA++D +P   R++K   + IV    ++ G    T  G+Y  +L D Y+A+   +L +  
Sbjct: 482 TALMDEYPLLLRKRKKIFILIVCFISFIIGFSNITQGGLYVFKLFDYYSASGMCLLYLVF 541

Query: 479 GECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPA 538
            E + I+W YGAE+F  +I+ MIG +  +W   W   W   TP   + +  F+ IE  P 
Sbjct: 542 FETVSISWFYGAERFYKNIEDMIGYRPCIW---WKLCWMFFTPLICLGVFTFSAIEMTPL 598

Query: 539 SYGHYVYPMWADAVGW 554
           + G YVYP+W   +GW
Sbjct: 599 TLGKYVYPLWGQVIGW 614



 Score =  132 bits (318), Expect = 4e-29
 Identities = 59/125 (47%), Positives = 83/125 (66%), Gaps = 2/125 (1%)

Query: 17  PLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAG 76
           P  EEI P+RG+W G+FDF            NVWRFPYLC  NGGGAFLIP+ + LV AG
Sbjct: 35  PKKEEI-PDRGSWKGKFDFLLSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFMTLVFAG 93

Query: 77  LPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTV 136
           +PL F+E S GQ+ ++G + V+ K  P+ +G+G   V++S  + +YY +IIAW ++Y+  
Sbjct: 94  IPLFFLETSLGQFTSVGGLGVW-KLMPMMKGVGIAAVVLSFWLNIYYIIIIAWALYYLFN 152

Query: 137 SFSSI 141
           SF S+
Sbjct: 153 SFRSV 157


>UniRef50_Q620M8 Cluster: Transporter; n=2; Caenorhabditis|Rep:
           Transporter - Caenorhabditis briggsae
          Length = 696

 Score =  342 bits (840), Expect = 2e-92
 Identities = 178/547 (32%), Positives = 281/547 (51%), Gaps = 17/547 (3%)

Query: 23  EPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFM 82
           E ER  +    +F            N+WRFP   + NGG AFLIP+     + G P ++ 
Sbjct: 56  EEEREGFGNGVEFVLTCLGLAVGLGNIWRFPMRAFENGGSAFLIPYLSCAFLFGFPAVYF 115

Query: 83  ELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIF 142
           E   GQY    P  ++ +  P   G+G+  V V+++V +YY +I++W   Y+   F   F
Sbjct: 116 EFLTGQYNGKSPPVIFRRVMPFLEGVGWMGVFVAALVAIYYIVIVSWISIYIVNIFRGDF 175

Query: 143 YQLPWQNCKAEWSTKH-CYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALR- 200
               W  C   W+    C       EC   +   +              I      A + 
Sbjct: 176 NI--WNKCDNPWNQMETCIDMLRQKECRVNHPPGWENATAKMIPEKMFFINGTCMDAKKF 233

Query: 201 -----RPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVV 255
                    E+YFT  ++  S+G+ +   I L +   +   WV+  L + KG +  GK+ 
Sbjct: 234 DGIEMLSATEQYFTRNIIDPSTGLYDFSGINLPILAAMTICWVLTALGILKGAKIMGKIS 293

Query: 256 YFTALFPYVVLVILFFRGVTLPGAITGILFYL-TPDFSQLANAQVWGDAAVQIFFALSPA 314
           Y + L PY ++V+LF RGVTLPGA  G+ +Y   PD+S++   + W +A  Q+ F+LS  
Sbjct: 294 YVSVLLPYFIVVVLFVRGVTLPGASDGLYYYFGKPDYSKIFLTRTWTEALKQLCFSLSVG 353

Query: 315 WGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQ 374
            GGLI+LSSY++ +NN + D+LIV + +   S   G  +FS +GFLA++  V V  VV  
Sbjct: 354 HGGLISLSSYSRKNNNVFKDALIVIIGDTVMSLVGGAAVFSTLGFLANQRGVQVPEVVKS 413

Query: 375 GAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKK 434
           G  LAF+VYPE +T++P+  LWS LFF+ML  LG  ++ AL++   + I D+ P +R+KK
Sbjct: 414 GFSLAFVVYPEAMTQMPLPWLWSFLFFLMLFLLGASTEIALVDVFCSCIYDQSPKYRKKK 473

Query: 435 GWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFC 494
             VV +   F Y  GL+F+TN+G+YW ++ D+YAA +S +   +GE I++ ++YG     
Sbjct: 474 WVVVTVWCFFLYCIGLVFSTNAGLYWFEMFDEYAAGFSSVCAVVGELIVMMYVYGFRNVR 533

Query: 495 GDIQRMIGRQSK-----LWVYLW--SAMWRIITPAALVFILVFNWIEYKPASYGHYVYPM 547
            DI  M+G         +  + W  +A W  I P    F++  +++   P +     YP+
Sbjct: 534 NDITEMLGEPKNKCTKAIGPHSWYFTANWMGIAPVIAAFLVALSFLRDYPYNGDANKYPI 593

Query: 548 WADAVGW 554
             D +GW
Sbjct: 594 VFDILGW 600


>UniRef50_Q4RY29 Cluster: Transporter; n=2; Tetraodontidae|Rep:
           Transporter - Tetraodon nigroviridis (Green puffer)
          Length = 641

 Score =  339 bits (834), Expect = 1e-91
 Identities = 175/488 (35%), Positives = 270/488 (55%), Gaps = 31/488 (6%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGG------AFLIPFTVMLVIAGL-P 78
           RG W  + +F            NVWRFPYLCY NGGG       + + F +  V   L P
Sbjct: 34  RGQWANKAEFLLAVAGQIIGLGNVWRFPYLCYKNGGGKARDSNGYSVAFVLFSVHGSLWP 93

Query: 79  LMFMELSFGQYAALGPVAVYNKFCPLF------RGLGYGMVIVSSIVMLYYNLIIAWTIF 132
            +F          +G   V+  FC ++       GLGY   ++     +YY +I+AW +F
Sbjct: 94  GLFFFCWCMTVGPIGHWKVHPSFCGVYLTSCALTGLGYASQVIILHGCVYYIVILAWALF 153

Query: 133 YMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQ--------CFNQS 184
           Y+  SF +   +LPW +C   W+T    +    D     N   + +         C   S
Sbjct: 154 YLLYSFQT---ELPWSHCNNTWNTGQRRA-ASVDAGFQNNSVPFFKNILCPPTETCILFS 209

Query: 185 YSVSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCL 244
           +      ++L K A    P  E++  +VL LS  +++ G +   +A+CL+A WVI + C+
Sbjct: 210 HQNQTGNSSLTKNATS--PVIEFWEREVLNLSDNLDKLGPVSWKLALCLVAIWVICYFCV 267

Query: 245 CKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAA 304
            KGV+S+GKVVY TA FPYV+L +L  RGVTLPGA  GI++YL PD  +LA+ QVW DA 
Sbjct: 268 WKGVKSTGKVVYLTATFPYVMLFVLLMRGVTLPGAGQGIIYYLKPDIGRLADPQVWMDAG 327

Query: 305 VQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHEL 364
            Q+FF+     G L  L SYNK++N+CY D+ ++ + N +TSF AG  IFSV+GF+A E 
Sbjct: 328 TQVFFSYGICLGSLTALGSYNKYNNDCYKDTFLLCLLNSSTSFMAGFAIFSVLGFMAEEQ 387

Query: 365 NVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAIL 424
            + +  V   G GLAFI YP  V+ +P+  LW++ FF+M++ LGLD+QF  +E + T++ 
Sbjct: 388 GMDISTVAQSGPGLAFIAYPRAVSMMPVPQLWAVCFFIMIIMLGLDTQFVSLEALMTSVT 447

Query: 425 DRFPNF---RQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANW-SVLIIAIGE 480
           D +P+      ++  ++  + +  +L GL+  T  G+Y  Q+ D Y+ +  ++L+++I +
Sbjct: 448 DLYPHLIRRGHRRKLLLLFICIACFLVGLVMVTPGGIYVFQVYDHYSCSGATLLLLSIFQ 507

Query: 481 CILIAWIY 488
            + I WIY
Sbjct: 508 SVAIGWIY 515



 Score = 41.5 bits (93), Expect = 0.066
 Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 4/66 (6%)

Query: 489 GAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGH-YVYPM 547
           GAE+F  +I+ M G+     ++++   W+ +TPA      +F+ I + P S     V P 
Sbjct: 551 GAERFTANIRHMTGKNP---MFIFKLCWKYLTPAVCTATFLFSVINWSPLSLVRGLVAPA 607

Query: 548 WADAVG 553
           WA A+G
Sbjct: 608 WATALG 613


>UniRef50_UPI0000660336 Cluster: Homolog of Homo sapiens "Solute
           carrier family 6 (neurotransmitter transporter, GABA),
           member 13; n=2; Takifugu rubripes|Rep: Homolog of Homo
           sapiens "Solute carrier family 6 (neurotransmitter
           transporter, GABA), member 13 - Takifugu rubripes
          Length = 615

 Score =  338 bits (830), Expect = 3e-91
 Identities = 185/493 (37%), Positives = 266/493 (53%), Gaps = 36/493 (7%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           RG W+ + ++            NVWRFPY CY NGGGAFLIP+ ++ V+ G+PL  +E S
Sbjct: 11  RGQWSSKAEYVLVVAGNVVGLGNVWRFPYPCYKNGGGAFLIPYCLLAVVFGVPLFLLETS 70

Query: 86  FGQYAALGPVAVYNKFCPL-----------------FRGLGYGMVIVSSIVMLYYNLIIA 128
            GQ+   G +  + K CPL                 F G+GY  ++V  +    Y ++  
Sbjct: 71  LGQFTQEGFITCWRKVCPLAQDIQNCFEKQRTLLTGFSGIGYAQLMV-KLASFTYIMVQV 129

Query: 129 WTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLR------QCFN 182
           W +FY+  SF S   +LPW  C   W+T   YS +     E+  G   L+       C +
Sbjct: 130 WALFYLVFSFRS---ELPWATCGNAWNTG--YSEDGFLIMESTFGKMNLQWNFISDNCRD 184

Query: 183 QSYSVSHNITALAKTALRRP--PAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIV 240
                + N TA  +T +  P   A +++  ++LGLS G+EE G +R  +A+CLL  W+  
Sbjct: 185 VWDFDAANQTA-NETRILDPTSAATQFWERRLLGLSGGVEELGSVRSELALCLLLCWLFC 243

Query: 241 FLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVW 300
           F  + KGV+S GKV Y TA+FP+V+LV LF R  TLPGA  GI  YL P   +LAN +VW
Sbjct: 244 FFSIRKGVRSMGKVAYLTAIFPFVLLVFLFARAATLPGASDGIKQYLIPQLGRLANIEVW 303

Query: 301 GDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFL 360
            +A  +I  + S   G LI L SYN ++NNCY D+  +      TSF AG ++FS++GFL
Sbjct: 304 TEAGSEILSSYSLTSGILIVLGSYNPYNNNCYRDAFWICALTSGTSFVAGFIVFSILGFL 363

Query: 361 AHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVT 420
           A   +VS+D V + G GL FI +P+    +P+   WSI FF+ML+ L  D+ F  +E V 
Sbjct: 364 AQVYSVSIDAVAESGPGLVFIAFPQAAALMPLPQFWSICFFLMLILLAADTHFVCVEAVI 423

Query: 421 TAILDRFPNFRQ---KKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKY-AANWSVLII 476
           T++ D FP   +   K   + F++ V  +L  LI  T  G Y  QL+D Y         +
Sbjct: 424 TSVSDLFPKLLRSPVKHEIISFLLCVSSFLVHLILATQGGNYIFQLIDYYGVTRLCDNFM 483

Query: 477 AIGECILIAWIYG 489
           AI EC+ + WI+G
Sbjct: 484 AICECLAVGWIFG 496



 Score = 40.7 bits (91), Expect = 0.12
 Identities = 23/74 (31%), Positives = 34/74 (45%), Gaps = 5/74 (6%)

Query: 481 CILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASY 540
           C LI+  +GA++    I  M G +  ++  L    W+I  PA      +   + YKP   
Sbjct: 520 CDLIS--HGADRLVLIIDDMTGHKPSIFFKL---CWKIFIPAFSGVCFLLYLVYYKPLHL 574

Query: 541 GHYVYPMWADAVGW 554
             YVYP W   +GW
Sbjct: 575 DRYVYPGWVPGLGW 588


>UniRef50_UPI0000E481CA Cluster: PREDICTED: similar to solute
           carrier family 6 (neurotransmitter transporter,
           noradrenalin), member 2; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to solute carrier
           family 6 (neurotransmitter transporter, noradrenalin),
           member 2 - Strongylocentrotus purpuratus
          Length = 705

 Score =  332 bits (817), Expect = 1e-89
 Identities = 160/455 (35%), Positives = 260/455 (57%), Gaps = 26/455 (5%)

Query: 103 PLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSY 162
           P++ G+G+ +++++  V   YN++I+W+ +Y+  SF+    +LPW+ C  EW+T  C+  
Sbjct: 12  PVYAGVGWAVLVIAWYVGFSYNVVISWSFYYLFASFTG---ELPWRYCDKEWNTPLCFD- 67

Query: 163 EEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAEEYFTNQVL--GLSSGIE 220
                              N SY     ++     +    PA+EYF  ++L    S+G+ 
Sbjct: 68  ----------------DTMNASYVEIDGVSVWLNYSTGNAPAKEYFDLEMLRRDRSTGLF 111

Query: 221 ETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAI 280
           +   +   + +CL+  ++I++  + KGV++SGKVV+ TA  PY VL IL  RGVTLPGA 
Sbjct: 112 DLAGMSWQLPLCLILVFIILYFSIWKGVKTSGKVVWVTATLPYFVLTILLIRGVTLPGAG 171

Query: 281 TGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAV 340
            GI +YL P+F+ LA   VW DAAVQIF+++   +G  I  +SYNKF++N Y D++  A 
Sbjct: 172 DGIRYYLYPNFALLAKPTVWIDAAVQIFYSIGAGFGVHIAFASYNKFNSNVYRDAIFTAS 231

Query: 341 SNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILF 400
            N  TSFF+G  +FS++G+L+H+    +  V   G GL F VYPE +  +P +P WSI+F
Sbjct: 232 INCFTSFFSGFAVFSILGYLSHKTGKEISEVATDGPGLVFTVYPEAIATIPGAPFWSIIF 291

Query: 401 FVMLLTLGLDSQFALMETVTTAILDRFPN-FRQKKGWVVFIVAVFGYLGGLIFTTNSGMY 459
           ++ML+TLGLDS F   E + T ++D+FP  F++++ ++V  + V  +   LI  T  G+Y
Sbjct: 292 YIMLITLGLDSSFGGTEAIVTGLVDQFPKFFKKRREYLVLAIVVSFFFFTLINVTYGGIY 351

Query: 460 WLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRII 519
              L ++YAA+ S+L +   E   +AW YG  +F  DIQ MIG    +   +W   W+ +
Sbjct: 352 VFHLENEYAASTSLLFVVAIEVFAVAWFYGVNRFARDIQEMIGFLPSI---VWRICWKFV 408

Query: 520 TPAALVFILVFNWIEYKPASYGHYVYPMWADAVGW 554
           +   +  + + + +   P  Y  Y YP W + + W
Sbjct: 409 STTFVFVMFIVSMVLSTPLVYDEYTYPQWGNVLAW 443



 Score = 91.1 bits (216), Expect = 8e-17
 Identities = 41/144 (28%), Positives = 74/144 (51%), Gaps = 4/144 (2%)

Query: 412 QFALMETVTTAILDRFPNF-RQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAAN 470
           +F   E + T ++D+FP F ++++ ++V  + V  +   LI  T  G+Y   L ++YAA+
Sbjct: 496 KFGGTEAIVTGLVDQFPKFFKKRREYLVLAIVVSFFFFTLINVTYGGIYVFHLENEYAAS 555

Query: 471 WSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVF 530
            S+L +   E   +AW YG  +F  DIQ MIG    +   +W   W+ ++   +  + + 
Sbjct: 556 TSLLFVVAIEVFAVAWFYGVNRFARDIQEMIGFLPSI---VWRICWKFVSTTFVFVMFIV 612

Query: 531 NWIEYKPASYGHYVYPMWADAVGW 554
           + +   P  Y  Y YP W + + W
Sbjct: 613 SMVLSTPLVYDEYTYPQWGNVLAW 636


>UniRef50_Q7QGR3 Cluster: Transporter; n=1; Anopheles gambiae str.
           PEST|Rep: Transporter - Anopheles gambiae str. PEST
          Length = 622

 Score =  332 bits (816), Expect = 2e-89
 Identities = 188/516 (36%), Positives = 278/516 (53%), Gaps = 40/516 (7%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           ER  W    +F            NVW+FP   + NGGGAF+IP+ ++L++ G P+ ++E+
Sbjct: 42  EREKWDKGVEFLMSCIALSVGLGNVWKFPSTAFRNGGGAFVIPYLIVLLVVGRPIYYLEM 101

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
             GQ+++ G V VY+   P+ RG+G   ++   +V++YY   IA  I +   SF S    
Sbjct: 102 MMGQFSSRGSVKVYD-VSPIMRGIGIAQMVSICVVIVYYAATIATAIRFFVASFGS---P 157

Query: 145 LPWQNCKAEWSTK-HCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPP 203
           LPW +C   W+   +C +        A          FN S  V        KT+     
Sbjct: 158 LPWASCDVSWTGGFNCVNSSNTGPTPA----------FNNSLPV--------KTS----- 194

Query: 204 AEEYFTNQVLGLSSGIEETGEIRLG---MAMCLLAAWVIVFLCLCKGVQSSGKVVYFTAL 260
           AE Y+T+ V G   G+   GE  +    + +CLL  WV + + + KG++ SGKV YF AL
Sbjct: 195 AELYYTHSVTG--EGLLTAGEFGVPDWKLTLCLLFIWVAMTIMMVKGIRGSGKVAYFLAL 252

Query: 261 FPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLIT 320
           FPYVVL+       TL GA  G+ +++TPD+ QL NA VW +A  Q FF+LS  +GG+I 
Sbjct: 253 FPYVVLISFAIYAFTLEGAGQGLKYFITPDWDQLLNADVWKEAVSQCFFSLSICFGGVIA 312

Query: 321 LSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELN-VSVDRVVDQGAGLA 379
            SSYN FSNN Y D++I++  +  TS  +G ++FS+IG L H  N     +VV  G+GL 
Sbjct: 313 FSSYNNFSNNIYRDAMIISWLDTFTSLLSGALVFSIIGHLGHLTNETDYTKVVKPGSGLT 372

Query: 380 FIVYPEVVTRLPISP-LWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVV 438
           FI YP+ + +    P L+++LFF MLLTLG+ S   L+ +V TA+ D  P  +  K   V
Sbjct: 373 FITYPDALAKFEHVPNLFALLFFFMLLTLGVGSCTGLINSVLTALHDSTPRLKSWK--TV 430

Query: 439 FIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQ 498
             + V G+  GL+F T SG   L   D Y   +  L  AI E     W+YG  K   DIQ
Sbjct: 431 VTIGVLGFALGLLFVTPSGSKMLDYFDYYGVQFVTLTSAIFELFAFCWLYGIRKLTRDIQ 490

Query: 499 RMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIE 534
            M+ R++    +LW   W+++TPA L+ +L+   ++
Sbjct: 491 FMLKRRTG---FLWRFCWKLLTPAMLIVVLIIGLVK 523


>UniRef50_Q9W4S0 Cluster: Transporter; n=14; Eumetazoa|Rep:
           Transporter - Drosophila melanogaster (Fruit fly)
          Length = 662

 Score =  331 bits (814), Expect = 3e-89
 Identities = 195/557 (35%), Positives = 296/557 (53%), Gaps = 69/557 (12%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           ER +W  +  F            NVWRFPYL   NGGGAFL+P+ +ML I G+P+ ++EL
Sbjct: 53  ERESWDSKIMFLLATIGYAVGLGNVWRFPYLAQKNGGGAFLVPYFIMLCIQGIPIFYLEL 112

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
           + GQ    G + V+++  P   G+G    +VS IV           ++Y T+    + Y 
Sbjct: 113 AIGQRLRKGAIGVWSQVSPYLGGIGISSAVVSYIV----------ALYYNTIIAWCLIYL 162

Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPA 204
           L        W+           +C  +           ++++  H    +A +     P 
Sbjct: 163 LHSFESPLPWA-----------DCPTR---------LYKNFTYDHEPECVASS-----PT 197

Query: 205 EEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264
           + Y+    L  S  ++        MA+ L+ +W +V++C+ +G+ SSGK+VY TA+FPYV
Sbjct: 198 QFYWYRTTLQCSESVDMPENFNYHMAIALIVSWFLVYICMVQGITSSGKIVYMTAIFPYV 257

Query: 265 VLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSY 324
           VL+I FFRG+TL GA  G+    TP +  L +  VW +A  QIFF+L  A+GGLI  SSY
Sbjct: 258 VLIIFFFRGITLKGAADGVAHLFTPRWETLLDPVVWLEAGTQIFFSLGLAFGGLIAFSSY 317

Query: 325 NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLA--------HELNVSVDR------ 370
           N  +NNCY D+++V+++N  TS FAG+V+FSVIGF A         E N  V +      
Sbjct: 318 NPANNNCYRDAILVSLTNCGTSMFAGVVVFSVIGFKATATFDRCTEERNGLVAQNKTHNL 377

Query: 371 -VVD---------QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVT 420
            V D          G GLAFI++ E + + P + LW++LFF+ML TLG+DSQF  +E V 
Sbjct: 378 PVCDLQTELANSASGTGLAFIIFTEAINQFPGAQLWAVLFFLMLFTLGIDSQFGTLEGVV 437

Query: 421 TAILDR--FPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAI 478
           T+++D   FPN    K ++V  +        + F   +G Y  QLMD +A N+ +LIIA+
Sbjct: 438 TSLVDMKLFPNL--PKEYIVGALCFSCCTISMCFANGAGSYIFQLMDSFAGNFPLLIIAL 495

Query: 479 GECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPA 538
            EC+ I++IYG  +F  DI+ M G +     + W   W+ ++P A+V IL+ ++  Y+  
Sbjct: 496 FECLSISYIYGVRRFSDDIEMMTGSRPN---FYWMFCWKYLSPCAMVTILLASF--YQLL 550

Query: 539 SYGHYVYPMWADAVGWT 555
           + G   YP W  + G T
Sbjct: 551 TEGS-SYPAWIGSKGAT 566


>UniRef50_Q17EZ8 Cluster: Sodium/shloride dependent amino acid
           transporter; n=3; Culicidae|Rep: Sodium/shloride
           dependent amino acid transporter - Aedes aegypti
           (Yellowfever mosquito)
          Length = 613

 Score =  330 bits (812), Expect = 5e-89
 Identities = 179/573 (31%), Positives = 294/573 (51%), Gaps = 44/573 (7%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           R  WT   +F            NVWRFPY   NNGGGAF+IP+ V+L++ G PL ++E+ 
Sbjct: 46  RDKWTRNIEFLLSCVALSVGFGNVWRFPYTALNNGGGAFVIPYLVVLLVVGRPLYYLEMI 105

Query: 86  FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQL 145
            GQ+++ G V V++  CPL RG+G G  +    ++ YY  +++  + Y   SF    Y L
Sbjct: 106 VGQFSSRGCVKVFD-MCPLMRGVGVGQTVTMFTIVGYYAALLSLAMRYFVDSFQ---YTL 161

Query: 146 PWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAE 205
           PW  C+ +W                         C + S +  H    ++ +   +P A 
Sbjct: 162 PWSECRLDWD------------------------CVDSSKASIH----ISNSTTTKPSAV 193

Query: 206 EYFTNQVLGLSSGIEE-TGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264
            YFT  V     G+E   G     + +CLL +W+++ + + KG++SSGK  YF A+FPYV
Sbjct: 194 FYFTEIVTNQFPGLENGIGLPNYQLVLCLLVSWILITVLVIKGIKSSGKASYFLAIFPYV 253

Query: 265 VLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSY 324
           +L  L  R VTL GA  GI +++TP + +L + +VW +A  Q FF+L+   G +I  SS+
Sbjct: 254 ILFGLLIRAVTLDGAFEGIKYFITPQWDKLLDTEVWYEAVSQCFFSLTIGLGAVIVYSSF 313

Query: 325 NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYP 384
           N FSNN Y D++I++  +  TS  +G+++F V+G +A+  + +V  V+  G  L F+VYP
Sbjct: 314 NSFSNNIYRDAMIISWLDTFTSMLSGVIVFGVVGNVAYITDKNVTDVMKNGPELTFVVYP 373

Query: 385 EVVTRLPISP-LWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAV 443
           + + ++P  P  ++I+FF+M + LGL S   ++ T+ T+I DR+P  +  K  VV  +AV
Sbjct: 374 DAIAKMPTWPNFFAIMFFLMFILLGLGSNMGIVTTILTSIKDRYPGVKIWK--VVIGIAV 431

Query: 444 FGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGR 503
            G+  GL++ +  G Y L ++D Y   +  L++ + E     W+YG ++ C DI+ M+  
Sbjct: 432 GGFCCGLVYISPGGFYVLDVVDYYGVTFPTLVLVVLEAFTFCWLYGVDRICMDIKFMLNI 491

Query: 504 QSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGWTXXXXXXXX 563
            + ++   W   W   T + LV I      +Y+         P   +  GW         
Sbjct: 492 NTGIF---WRICWGFFTLSILVTITCMQIFKYEAKK-----VPREYNVFGWCLFGVTVLQ 543

Query: 564 XXXXXXDQICSGPDDLTIMEKARVLARPTEEWG 596
                     + P+   +  K     +PT++WG
Sbjct: 544 VVVWAVCATANQPNRSGLCGKLCDALKPTKDWG 576


>UniRef50_Q9XUG5 Cluster: Transporter; n=3; Caenorhabditis|Rep:
           Transporter - Caenorhabditis elegans
          Length = 706

 Score =  326 bits (801), Expect = 1e-87
 Identities = 181/571 (31%), Positives = 281/571 (49%), Gaps = 28/571 (4%)

Query: 10  DEEKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFT 69
           D   SK     + +P RG W  + +F            N+WRFP   YNNGG AFL+P+ 
Sbjct: 28  DSGSSKEIEESQADPCRGAWGNQIEFLLSTLGMAVGLGNIWRFPTRAYNNGGSAFLVPYV 87

Query: 70  VMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAW 129
              ++ GLP +++E   GQY       ++ +F P+ +G+G+  V VSS+V +YY +II W
Sbjct: 88  ACALLFGLPAVYLEFLLGQYHRTTAPIIFRRFAPILQGVGWMAVAVSSLVAIYYIIIIGW 147

Query: 130 TIFYMTVSFSSIFYQLPWQNCKAEWST-KHCYSYEEADECEAQNGT--------YYLRQC 180
           +  YM        +   W  C   W+  + C        C + N T          L   
Sbjct: 148 STVYMASIVMG--HTSKWNRCGNSWNNAESCVDSGLQPLCASFNATGNETSPVWANLSSE 205

Query: 181 FNQSYSVSHNITALAKTALRR------PPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLL 234
               + +  N +   K  L           E+YF + V+  + G  E   I       + 
Sbjct: 206 GRGKFYIYLNTSCYDKVDLEFNKTKMIAATEQYFFDYVVKPTDGFLEFSSINFKSFFGMN 265

Query: 235 AAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYL-TPDFSQ 293
           A W+IV L L KGV   GK  Y     PY ++++LFFRG+TL GA  GI +YL  PD+S+
Sbjct: 266 ACWLIVVLILWKGVGYMGKASYVIVTLPYFIIILLFFRGITLDGAEDGIYYYLGNPDWSK 325

Query: 294 LANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVI 353
           +     WG+A  Q+ F+L   +GGLI ++S++K +NNC+ D+LIV + +   S   G  +
Sbjct: 326 VFMPATWGEALKQLCFSLGIGYGGLIGMASFSKPNNNCFRDALIVIIGDTMMSLVGGAAV 385

Query: 354 FSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQF 413
           FS +GFLA +   SV  VV+ G  LAF+ +PE + R+P+  LWS LFF+ML  LG+ ++ 
Sbjct: 386 FSTLGFLAKKKGCSVAEVVNDGFSLAFVAFPEALGRMPLPELWSFLFFLMLFFLGISTEV 445

Query: 414 ALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSV 473
           A +    ++I D+F N R++K  V  +  +  Y+ G++  T+ G YW  + D+YAA  S 
Sbjct: 446 AYVNVFCSSICDQFVNLRKRKWLVAVLWCLVLYVLGVVMVTDGGFYWFIMFDEYAAGVSS 505

Query: 474 LIIAIGECILIAWIYGAEKFCGDIQRMIGRQSK---LWVYLWSAM----WRIITP---AA 523
                 E +++A++YG      D++ M G        W+   S      W  +TP   + 
Sbjct: 506 CCAVTAEVLIVAYVYGRRNQLADMKEMFGESKNKCTSWIGQHSPYFGFNWMFVTPVLGSI 565

Query: 524 LVFILVFNWIEYKPASYGHYVYPMWADAVGW 554
           L+ +       Y+       +YP+  D VGW
Sbjct: 566 LIVLASIRQYPYQTDENKPNMYPLAFDIVGW 596


>UniRef50_O76188 Cluster: Potassium coupled amino acid transporter;
           n=2; Manduca sexta|Rep: Potassium coupled amino acid
           transporter - Manduca sexta (Tobacco hawkmoth) (Tobacco
           hornworm)
          Length = 634

 Score =  322 bits (791), Expect = 2e-86
 Identities = 185/534 (34%), Positives = 280/534 (52%), Gaps = 38/534 (7%)

Query: 24  PERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFME 83
           PER  W+   +F            NVWRFP++ Y NGGGAFL+P+ ++L++ G P+ ++E
Sbjct: 49  PERMVWSNNIEFLMSCIATSVGLGNVWRFPFIAYQNGGGAFLVPYIIVLLLVGKPVYYLE 108

Query: 84  LSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFY 143
              GQ+++   V +++   P  +G GY   +    ++           +Y+ +    +FY
Sbjct: 109 CVLGQFSSRNSVKIWS-ISPAMKGTGYAQAVGCGYILS----------YYVVICGLCLFY 157

Query: 144 QLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPP 203
                     W+   C    E + C   + T         +  V  NIT    +A     
Sbjct: 158 LAMSFQATLPWAI--CQP--EWENCVPSDPTL--------AAGVG-NITNGTSSA----- 199

Query: 204 AEEYFTNQVLGLSSGIEE-TGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFP 262
            E YF   VL  S GIE   G     + +CL  AW++VF  + +GV+SSGK  YF ALFP
Sbjct: 200 -ELYFLRTVLQQSDGIEGGLGAPIWYLVLCLFIAWLMVFGVVARGVKSSGKAAYFLALFP 258

Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322
           YVV++ LF   V LPGA  GILF++TPD+ +L    VW  A  Q+FF+LS   G +I  S
Sbjct: 259 YVVMITLFITTVLLPGATDGILFFVTPDWWKLLELGVWYAAITQVFFSLSVCTGAIIMFS 318

Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQ-GAGLAFI 381
           SYN F  N Y D+LIV   +  TSF +G  IF ++G LA+ELN  V  V+   G  LAFI
Sbjct: 319 SYNGFKQNVYRDALIVTTLDTFTSFLSGCTIFGILGNLAYELNSDVGDVIGSGGTSLAFI 378

Query: 382 VYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIV 441
            YP+ + +     L+S+LFF+M+  LG+ S  AL+ T+ T ++D FP  R    ++  + 
Sbjct: 379 SYPDAIAKTFQPQLFSVLFFLMMSVLGIGSSVALLSTLNTVVMDAFP--RVPTVYMSALS 436

Query: 442 AVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMI 501
              G+L GL++ T  G + L+L+D Y   + VL  AI E   + WIYG E  C DI+ M+
Sbjct: 437 CTCGFLLGLVYCTPGGQFILELVDHYGGTFLVLFCAISELAGVFWIYGLENLCLDIEFMM 496

Query: 502 GRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYG-HYVYPMWADAVGW 554
           G+ +    + W   W I+TP  ++ + ++  + ++   +G  YVYP+     G+
Sbjct: 497 GKTTG---FYWRLCWGIVTPGMMIIVFIYALLSFENLVFGDFYVYPVAGYVAGY 547


>UniRef50_UPI000065F69C Cluster: Homolog of Homo sapiens "Solute
           carrier family 6 (Neurotransmitter transporter, GABA),
           member 13; n=1; Takifugu rubripes|Rep: Homolog of Homo
           sapiens "Solute carrier family 6 (Neurotransmitter
           transporter, GABA), member 13 - Takifugu rubripes
          Length = 601

 Score =  315 bits (774), Expect = 2e-84
 Identities = 155/391 (39%), Positives = 231/391 (59%), Gaps = 17/391 (4%)

Query: 107 GLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEAD 166
           G+GYG +++     + Y +I++W + Y+  SF S   QLPW  C   W++       + D
Sbjct: 101 GIGYGGILILIYSCMTYIIILSWALLYLIFSFRS---QLPWGTCNNYWNSG------KID 151

Query: 167 ECEAQNGTYYLRQCFNQSYSV----SHNITALAKTALRRPPAEEYFTNQVLGLSSGIEET 222
                NG      C   S S       N +  +        A E++  +VL +S GIEE 
Sbjct: 152 PGCTFNGFPLSCPCLKISLSEFCISGQNTSGWSNQTNTTSAATEFWERRVLAISGGIEEI 211

Query: 223 GEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITG 282
           G +R  + +CL+  WVI + C+ KGV+++GKVVY TA  PYV+L++L  RG+TLPGA+ G
Sbjct: 212 GSVRWEVLLCLMVMWVICYFCIWKGVKTTGKVVYLTATLPYVMLLVLLVRGLTLPGALDG 271

Query: 283 ILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSN 342
           +L+YL P  S++ + QVW +AA QIFF+ S   G LI LSSYN +++NCY  SL + + N
Sbjct: 272 VLYYLLPQVSRMTDPQVWMEAAAQIFFSYSLGVGSLIVLSSYNNYNDNCYKSSLYLCLLN 331

Query: 343 IATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFV 402
             TS  AG  +FSV+GF+AHE  V +  V + G GLAFI YP+ +  +P+  LWS+ FF+
Sbjct: 332 SCTSVVAGFAVFSVLGFMAHEQGVPIADVAESGPGLAFIAYPQAIAMMPLPQLWSVCFFI 391

Query: 403 MLLTLGLDSQFALMETVTTAILDRFPNFRQKKGW---VVFIVAVFGYLGGLIFTTNSGMY 459
           M++ LGLD+QF  ME V T+I+D FP   ++ G     +F+  +F +   L+  T  GMY
Sbjct: 392 MIIVLGLDTQFLAMEVVLTSIMDMFPKQMRRAGQRERFLFVFCLFCFFSQLVVITEGGMY 451

Query: 460 WLQLMDKYAANWS-VLIIAIGECILIAWIYG 489
             QL+D YA N + +L + I E + + W++G
Sbjct: 452 VFQLLDHYACNGACILFLCIFESLALGWLFG 482



 Score = 50.4 bits (115), Expect = 1e-04
 Identities = 19/38 (50%), Positives = 22/38 (57%)

Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGG 62
          ERG+W  R ++            NVWRFPYLCY NGGG
Sbjct: 3  ERGHWDKRVEYILAVAGAVVGLGNVWRFPYLCYKNGGG 40


>UniRef50_UPI0000DB790C Cluster: PREDICTED: similar to CG5549-PA;
           n=1; Apis mellifera|Rep: PREDICTED: similar to CG5549-PA
           - Apis mellifera
          Length = 436

 Score =  313 bits (769), Expect = 8e-84
 Identities = 148/319 (46%), Positives = 208/319 (65%), Gaps = 1/319 (0%)

Query: 204 AEEYFTNQVLGLSSGI-EETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFP 262
           +EEYF + VLG+     E  G +R  +  CL  AW+I FLCL +GVQS GK+VYFTALFP
Sbjct: 69  SEEYFNDYVLGIRGATWEHFGGVRWELLGCLTLAWIICFLCLMRGVQSIGKIVYFTALFP 128

Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322
           Y +L+ L  RGVTL GA+ G L+++ P +S L +  VW DAA Q+F++L    G LITLS
Sbjct: 129 YAMLIALLIRGVTLEGALDGSLWFIMPKWSTLQSTNVWADAASQVFYSLGIGCGSLITLS 188

Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIV 382
           SY+ F+NNC+ D++ V  +N+ATS FAG VIFS++GFLA ++ VSV+ V+  GA LAFI 
Sbjct: 189 SYSNFNNNCHRDAIFVTFTNLATSIFAGFVIFSIMGFLARQMGVSVEEVIQSGAALAFIA 248

Query: 383 YPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVA 442
           YPE V R+P+  +W++LFFVML  LG+ SQFA ++ + TAILD  P+ R+++  VVF + 
Sbjct: 249 YPEAVVRMPLPNVWAVLFFVMLFILGIGSQFAGVQAINTAILDLRPDLRKRESLVVFGIC 308

Query: 443 VFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIG 502
           V  +   +    + G+Y   LMD   A+W++L+I I E  ++ W YG  KF  +I  M  
Sbjct: 309 VTCWFLAIPMVFDGGIYLFTLMDWNTASWAILLIGIAEVGVVGWCYGCNKFLRNIAEMQM 368

Query: 503 RQSKLWVYLWSAMWRIITP 521
           R + L    W   W ++ P
Sbjct: 369 RFNLLLRRYWWLSWVVLAP 387


>UniRef50_UPI0000E4A4BA Cluster: PREDICTED: similar to glycine
           transporter type 2b; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to glycine
           transporter type 2b - Strongylocentrotus purpuratus
          Length = 458

 Score =  312 bits (766), Expect = 2e-83
 Identities = 166/396 (41%), Positives = 240/396 (60%), Gaps = 20/396 (5%)

Query: 210 NQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVIL 269
           ++V  L+ GI++ G +   +    LAAW+IV+LC+ KGV+S+GKVVYFTA FPY+VL IL
Sbjct: 3   HRVHRLTDGIDDMGTMNWDVFGAFLAAWIIVYLCIIKGVKSAGKVVYFTATFPYIVLFIL 62

Query: 270 FFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSN 329
             RGVTLPGA  GI+FYL PDF +LA+ + W DAA QIF++L  ++G LIT +SYNKF N
Sbjct: 63  LIRGVTLPGAAKGIIFYLKPDFQKLASPEPWKDAANQIFYSLGMSFGSLITFASYNKFKN 122

Query: 330 NCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTR 389
           NCY D+++V+  N  TS FAG VIFSV+GF+A +  + V  VV  G GLAF VYPE ++R
Sbjct: 123 NCYKDAIMVSFINCGTSIFAGFVIFSVLGFMAQDSGLEVKDVVASGPGLAFKVYPEALSR 182

Query: 390 LPISPLWSILFFVMLLTLGLDSQ-----FALMETVTTAILDRFPNFRQKKGWVVFIVAVF 444
           LP+  LWSILFF MLLTLGLDSQ      +L + ++ ++    P    +  W+   +++F
Sbjct: 183 LPVPQLWSILFFFMLLTLGLDSQVQWMLLSLFQWMSISLFQWMPLSLDQ--WMP--LSLF 238

Query: 445 GYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQ 504
                LI      M   Q        W  L + +G C+ + ++ G ++F GDI+ MIG  
Sbjct: 239 AMSEALITAIADEMSPAQ-----RKKWKWL-VTLGVCVAL-FLCGLKRFVGDIRAMIGYD 291

Query: 505 SKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGWTXXXXXXXXX 564
             +++Y W   W +++P A++ I+V  ++ Y PA YG YV+P WA A+GW          
Sbjct: 292 --VFIY-WQICWAVLSPLAMLLIVVLGFVFYVPAYYGDYVFPDWAQAIGWLMAFASFLVV 348

Query: 565 XXXXXDQICSGPDDLTIMEKARVLARPTEEWGQAGS 600
                  +    +  T +++   L +PT +WG A +
Sbjct: 349 PAYSIYAMIFLAEG-TFLKRVSFLMKPTWDWGPASN 383


>UniRef50_P90890 Cluster: Transporter; n=2; Caenorhabditis|Rep:
           Transporter - Caenorhabditis elegans
          Length = 768

 Score =  305 bits (748), Expect = 3e-81
 Identities = 170/541 (31%), Positives = 276/541 (51%), Gaps = 43/541 (7%)

Query: 48  NVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRG 107
           N+WRFP + Y NGG +FLI + +   +  +P + ME + GQYAA  P AV+ +  P   G
Sbjct: 130 NIWRFPTVAYQNGGTSFLIVYIICAFVFAVPAIHMEFALGQYAAKSPPAVFRRIMPALEG 189

Query: 108 LGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADE 167
           +G+   IV +++ +YY ++I+W + Y+     +IFY      C   W+  +CY   E   
Sbjct: 190 VGWMTCIVGAVIGVYYMILISWIVLYII----NIFYVNNMGRCDNPWNQNNCYDGSEQSR 245

Query: 168 CEAQNGTYYLRQCFNQSYSVSHNITALAKTALRR-----------------PPAEEYFTN 210
           C   N   Y     N S  ++  +  L  +  +R                    E++F+ 
Sbjct: 246 C---NKGLYSNMTANASSFLNTTMAPLMSSGSKRILYINGKCQDATNMSVEVGTEQFFSK 302

Query: 211 QVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILF 270
            V+  S+G  +   I L +   +   WVI  + L +G+++ GK+ Y T + PY ++V L 
Sbjct: 303 SVIRPSAGFTDFNSINLPILGAVALCWVIAAVVLIRGMKAIGKLSYVTVILPYFIIVSLL 362

Query: 271 FRGVTLPGAITGI--LFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFS 328
             GV+LPGA  G+  LF  T DF+ L   + W  A  QI F+LS   GGL+ ++SYNK +
Sbjct: 363 ICGVSLPGAKDGLYHLFGQT-DFNYLYKRETWTAALQQICFSLSIGQGGLMNIASYNKKT 421

Query: 329 NNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVS------VDRVVDQGAGLAFIV 382
            N Y D  I+   +   S   G+ +FS +GFLA+E  ++       + +V +G  LAFIV
Sbjct: 422 YNWYRDVYIIVFLDTLMSILGGITVFSTLGFLAYERGINSTDIDAFNHIVKEGHALAFIV 481

Query: 383 YPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVA 442
           Y E +  +P+  LW  LFF+ML  LG+ ++  ++E V + + DRF   R+++   V  V+
Sbjct: 482 YTEAIAEMPVPYLWYALFFIMLFLLGISTEVVIVEIVCSCLADRFRYLRERRWLTVLSVS 541

Query: 443 VFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIG 502
              +L GL+ TT++G YW  + D+Y+   S        C+ + W YG   F  DI  M G
Sbjct: 542 AVFFLLGLVMTTDAGFYWFDMFDEYSTGISATFGTAIMCMTVFWCYGTNHFREDIAVMWG 601

Query: 503 RQSKLWV--------YLWSAMWRIITP-AALVFILVFNWIEYKPASYGHYVYPMWADAVG 553
            + + W+        Y W+ +W+ +TP  +L+ + ++ W +  P      +YP   DA+G
Sbjct: 602 -EPESWLATCLGPAAYFWTLIWKFVTPVCSLLMMGLWIWEKKYPHKGDGKIYPPVFDALG 660

Query: 554 W 554
           W
Sbjct: 661 W 661


>UniRef50_Q59DZ2 Cluster: Transporter; n=4; Sophophora|Rep:
           Transporter - Drosophila melanogaster (Fruit fly)
          Length = 739

 Score =  302 bits (741), Expect = 2e-80
 Identities = 174/500 (34%), Positives = 258/500 (51%), Gaps = 22/500 (4%)

Query: 120 MLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQ 179
           + YY  ++A    Y   SF +    LPW  C+AEW   HC +       +A N +     
Sbjct: 243 LTYYAALVAIIGRYFIESFRN---PLPWSTCRAEWGI-HCINSAP----DASNWSQ---- 290

Query: 180 CFNQSYSVSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEE-TGEIRLGMAMCLLAAWV 238
               +     N T  ++       +E YF  +VL     IEE  G     + + L  AW 
Sbjct: 291 -LESNDQRPQNYTMKSQNDRVITSSEWYFVKEVLHEKPNIEEGIGLPNWELVIGLFIAWS 349

Query: 239 IVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQ 298
            VF  + +GV+SSGK  YF ALFPYV++ +L  R VTLPG+I GI +++ P + ++ + +
Sbjct: 350 CVFFIIRRGVKSSGKASYFLALFPYVIMGVLLVRAVTLPGSIDGIYYFIKPQWGKILDPK 409

Query: 299 VWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIG 358
           VW  A  Q F++LS  +G +I  SS+NKF +N + D+ IV   +  TS  AG  IF ++G
Sbjct: 410 VWYAAVTQCFYSLSVCFGNIIMYSSFNKFGHNVHRDAAIVTGLDTMTSLLAGFTIFGILG 469

Query: 359 FLAHELNV-SVDRVVDQGAGLAFIVYPEVVTRLPISP-LWSILFFVMLLTLGLDSQFALM 416
            LAHE+    +  VV  GAGLAFI YP+ + +    P ++S+LFF+ML  LG+ S  A+ 
Sbjct: 470 HLAHEIGTDDIGSVVKGGAGLAFISYPDAIAKFKNLPQIFSVLFFLMLFVLGIGSNIAMT 529

Query: 417 ETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLII 476
               TAI DRFPNF Q +     ++AV  +  GL++ T  G Y L L+D + A+   L++
Sbjct: 530 SCSVTAIRDRFPNFGQWQ--CSLLIAVVSFFIGLMYITPGGQYMLTLVDFFGASMIALVL 587

Query: 477 AIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYK 536
            I E   I WIYG ++ C DI+ M+GR+  L+   W   W IITP  +  IL++ +  Y+
Sbjct: 588 GIAELYTIGWIYGTDRLCKDIEFMLGRKVGLY---WRLCWSIITPLIMTVILIYFYATYQ 644

Query: 537 PASYGHYVYPMWADAVGWTXXXXXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWG 596
           P +Y + VYP W+ ++GW                 I   P   T+  K R    P + WG
Sbjct: 645 PLTYNNIVYPNWSYSIGWLITAFGILQLPIWMIVAIVRDPGQ-TLGAKIRGAFTPKKNWG 703

Query: 597 QAGSTATCLSTLRVETELSP 616
            +           +E EL+P
Sbjct: 704 PSDPLLREQYHKEIENELTP 723



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 54/176 (30%), Positives = 82/176 (46%), Gaps = 38/176 (21%)

Query: 10  DEEKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFT 69
           D+E +K P       ER  W    +F            NVWRFP+   +NGGGAFLIP+ 
Sbjct: 40  DQEAAKVP------EERATWGKGVEFLMSCIAMSVGLGNVWRFPFTALDNGGGAFLIPYL 93

Query: 70  VMLVIAGLPLMFMELSFGQYAALGPVAVYN-------------------------KFCPL 104
           ++L + G P+ ++E+  GQ+++ G V V++                         + CP 
Sbjct: 94  IVLFLIGKPIYYLEMVIGQFSSRGSVKVFDLCPAMKEYDNSELQNLHRHSVHQLARSCPK 153

Query: 105 F--RGLGYGM--VIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWST 156
           +    +G G+  VI  S+V  YY  I+  T+ Y+  SF S    LPW  C+ EW +
Sbjct: 154 YATTSIGVGIGQVISISMVTTYYVAIMGITLRYLYESFRS---PLPWSECRPEWES 206


>UniRef50_UPI0000E49DFE Cluster: PREDICTED: similar to taurine
           transporter, partial; n=9; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to taurine
           transporter, partial - Strongylocentrotus purpuratus
          Length = 818

 Score =  291 bits (714), Expect = 4e-77
 Identities = 172/496 (34%), Positives = 266/496 (53%), Gaps = 31/496 (6%)

Query: 64  FLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYY 123
           FL+P+ +  +    PL+F+E++ GQY + GP+  + K CP+F+G+G    +V+    +YY
Sbjct: 123 FLVPYFLCSLFLATPLLFLEMALGQYTSSGPIRAW-KICPIFQGIGVATTVVAWWRNIYY 181

Query: 124 NLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQ 183
           N+I+AWT++Y+  S   I  +LPW  C  EW+T  C +Y   +E    NGTY     +N 
Sbjct: 182 NVILAWTLYYLYSS--CIGGELPWARCNNEWNTASCLNY--GNEWVCVNGTYIPIDKWNA 237

Query: 184 --------SYSVSHNITALAKT------ALRRPPAEEYFTNQVLGLSSGIEETGEIRLGM 229
                   S+S  +    L  +       L   PA+E++  +VLG  +G    G +   +
Sbjct: 238 PPEESPAPSWSSWNEAVPLDDSDQCGNYPLTTNPAQEFWRIKVLG-QTGTGGRGIVG-HL 295

Query: 230 AMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTP 289
           A+ L  AW +V+  L KGV+ SGKV YFT  F ++V  +L  RG+TLPGA  G++FYL P
Sbjct: 296 ALTLFLAWTLVYFGLRKGVKWSGKVAYFTVPFIHLVFAVLMIRGITLPGAYDGLIFYLKP 355

Query: 290 DFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFA 349
             S+L NAQ W  A  ++F++ S   G    L S+NKF  N Y DS+I A  N+ TS ++
Sbjct: 356 IPSRL-NAQAWIAAGTEVFYSFSIGLGAFTALGSFNKFHYNFYRDSIIAAYLNVWTSIYS 414

Query: 350 GLVIFSVIGFLAHELNVSVDRVVDQGAGLA--FIVYPEVVTRLPISPLWSILFFVMLLTL 407
           G+++F+ +G  A+   +S   ++  G+G    F V+P     LP+  +WSI FF+ +LT+
Sbjct: 415 GIIVFTFLGVEAYSEGISPGVIIADGSGSGRFFKVFPRSFAALPVPRVWSIFFFLAVLTI 474

Query: 408 GLDSQFALMETVTTAILDRFPNFRQKKGW-VVFIVAV--FGYLGGLIFTTNSGMYWLQLM 464
           GL+SQ   ++   T++LD FP + +   +  VF++ V    +L GL   T  G Y L L 
Sbjct: 475 GLNSQLVTVKAFITSVLDLFPTWLRIGYYKEVFVLGVCFLNFLIGLSMVTQDGEYVLWLF 534

Query: 465 DKYAANWSVLI-IAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAA 523
           D Y +    LI I   E I I W+YG  KF  +I  M+  Q   W  +    W    P  
Sbjct: 535 DAYGSGIFPLIWICFFESIAIGWVYGVRKFSFNIAEMLRWQQIQWYII---CWIATVPVI 591

Query: 524 LVFILVFNWIEYKPAS 539
            +F+ + N + +   S
Sbjct: 592 ALFVWINNIVSWSTLS 607



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 36/92 (39%), Positives = 56/92 (60%), Gaps = 5/92 (5%)

Query: 84  LSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFY 143
           ++ GQY + GP+  + K CP+F+G+G    +V+    +YYN+I+AWT++Y+    S I  
Sbjct: 1   MALGQYTSSGPIRAW-KICPIFQGIGVATTVVAWWRNIYYNVILAWTLYYL--YSSCIGG 57

Query: 144 QLPWQNCKAEWSTKHCYSYEEADECEAQNGTY 175
           +LPW  C  EW+T  C +Y   +E    NGTY
Sbjct: 58  ELPWARCNNEWNTASCLNY--GNEWVCVNGTY 87


>UniRef50_Q5XIV7 Cluster: Transporter; n=2; Eutheria|Rep:
           Transporter - Rattus norvegicus (Rat)
          Length = 509

 Score =  287 bits (704), Expect = 6e-76
 Identities = 171/485 (35%), Positives = 258/485 (53%), Gaps = 54/485 (11%)

Query: 21  EIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLM 80
           +IE ER  W  +  +            N+WRFPYLC+ +GGGAFLIP+ + LV  G+PL 
Sbjct: 12  DIEDERPKWDNKLQYLLSCIGFAVGLGNIWRFPYLCHTHGGGAFLIPYFIALVFEGIPLF 71

Query: 81  FMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSS 140
           ++EL+ GQ    G + V+    P   G+G G   VS +V LYYN I+ W +++   SF  
Sbjct: 72  YIELAIGQRLRRGSIGVWKTISPYLGGVGLGCFSVSFLVSLYYNTILLWVLWFFLNSFQ- 130

Query: 141 IFYQLPWQNCKAEWSTKHCYSYEEADECEAQ-NGTYYLRQCFNQSYSVSHNITALAKTAL 199
             + LP       WST           C    N T ++++C   S +VS+          
Sbjct: 131 --HPLP-------WST-----------CPLDLNRTGFVQEC-QSSGTVSY---------- 159

Query: 200 RRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTA 259
                  ++  Q L ++S I  TG I+  + +CL+A W  V+LC+ +G++S+GKV+YFTA
Sbjct: 160 -------FWYRQTLNITSDISNTGTIQWKLFLCLVACWTTVYLCVIRGIESTGKVIYFTA 212

Query: 260 LFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLI 319
           LFPY+VL I   RG+TLPGA  G+ +  TP+   L N +VW DAA QIFF+LS A+GG I
Sbjct: 213 LFPYLVLTIFLIRGLTLPGATEGLTYLFTPNMKILQNPRVWLDAATQIFFSLSLAFGGHI 272

Query: 320 TLSSYNKFSN-NCYIDSLIVAVSNIATSFFAGLVIF---------SVIGFLAHELNVSVD 369
             +SYN+  N    I+       +I+   +  ++++         + +      L   +D
Sbjct: 273 AFASYNQPRNILSLINEFDFPELSISRDEYPSVLMYLNATQPERVARLPLKTCHLEDFLD 332

Query: 370 RVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDR--F 427
           +    G GLAFIV+ E V  +P + +WS+LFF ML TLGL S F  ME V T + D    
Sbjct: 333 KSA-SGPGLAFIVFTEAVLHMPGASVWSVLFFGMLFTLGLSSMFGNMEGVITPLFDMGIL 391

Query: 428 PNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWI 487
           P    K+  +  +V    +L  + FT  SG YWL++ D +AA+ +++I A  E + +  +
Sbjct: 392 PKGVPKE-TMTGVVCFICFLSAICFTLQSGSYWLEIFDSFAASLNLIIFAFMEVVGVIHV 450

Query: 488 YGAEK 492
           YG ++
Sbjct: 451 YGIKR 455


>UniRef50_Q4SBR5 Cluster: Transporter; n=1; Tetraodon
           nigroviridis|Rep: Transporter - Tetraodon nigroviridis
           (Green puffer)
          Length = 545

 Score =  276 bits (676), Expect = 2e-72
 Identities = 152/494 (30%), Positives = 256/494 (51%), Gaps = 25/494 (5%)

Query: 18  LSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGL 77
           +SEE    R  W  + +F             +W FP+ C + GG  FLIP+ V L   G+
Sbjct: 19  VSEEAARPRAKWANKMEFFLCASTQTTSYNFMWIFPFFCIHYGGAVFLIPYCVSLFFCGM 78

Query: 78  PLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLII-AWTIFYMTV 136
           PL+ + L+ GQY +   V  + K CP+F+G+G   +++   + +   L++  W++ Y+  
Sbjct: 79  PLLLLGLAMGQYTSESGVTAWKKICPMFQGIGIASMVILIYMSISSELLMPVWSLLYL-- 136

Query: 137 SFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAK 196
            ++S+   LPW  C   W+T+ C S           G     +  N +    ++I+  A+
Sbjct: 137 -YNSVKSPLPWTTCDNAWNTEMCVSRTNPASSNTSVGQRD-DEWMNLTTGF-YDISETAE 193

Query: 197 TALRR---PPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGK 253
               R   P   +   N   G          +   +  CL   WV+ + C  KG++ +GK
Sbjct: 194 MEFWRSINPTQTDNAWNDKFG--------SPLHWSLIPCLFIVWVLCYFCTWKGIKYTGK 245

Query: 254 VVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWG-DAAVQIFFALS 312
           ++Y  A FPY++L+ILF R VTLPGA  G+ +   PDF   ++  +W    +  + FA S
Sbjct: 246 IMYMVA-FPYLLLIILFIRSVTLPGAGEGLKYLFIPDFHVFSSPYIWMFSVSYSLHFATS 304

Query: 313 PAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVV 372
              G   TL SYNK++N+CY D+LI+   ++AT  F   + FS IGF+AH    S + V+
Sbjct: 305 T--GVRTTLGSYNKYNNDCYRDTLILCALHVATIIFFNCIAFSFIGFVAHIEEASFNDVM 362

Query: 373 DQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNF-R 431
             G  + F++ P+ ++ +  S  W++L+F M +   L  Q  L+E++ T + D  P + R
Sbjct: 363 RTGTDMLFVLVPKALSLVAGSSFWTVLYFFMTILFTLSHQIVLVESLATNVNDLLPRYLR 422

Query: 432 QKKGWVVFIVAVFG--YLGGLIFTTNSGMYWLQLMDKYAANWSV-LIIAIGECILIAWIY 488
           ++    + ++AV G   L  L+  T  G+++LQL+D YA ++++   I   E I++AW+Y
Sbjct: 423 KRHARELVVLAVCGLCLLVWLLIITKGGLFFLQLVDYYALSFTITYFIVCFETIVVAWVY 482

Query: 489 GAEKFCGDIQRMIG 502
           GA++F  +I  MIG
Sbjct: 483 GADRFYDNIADMIG 496


>UniRef50_A7RFF4 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 523

 Score =  275 bits (674), Expect = 3e-72
 Identities = 147/349 (42%), Positives = 209/349 (59%), Gaps = 25/349 (7%)

Query: 201 RPPAEEYFTNQVLGLSSGIEETGE-IRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTA 259
           R P+  YF +  L +S+ IE+TG  I + +A CL+ AW++ +LC+ KG++SSGKVVYFTA
Sbjct: 138 RDPSAYYFYHHALEVSTSIEDTGVGINVKLAGCLVFAWILTYLCVVKGIKSSGKVVYFTA 197

Query: 260 LFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLI 319
            FPY++L+ILFFRGVTL GA  GI    TPD+  L +A +W DAA Q+FF LS  +G LI
Sbjct: 198 TFPYIILIILFFRGVTLEGAGNGIKTLFTPDWGLLLDANIWKDAATQMFFTLSLGFGALI 257

Query: 320 TLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRV-------- 371
             +SY    N    D   V + N  TS FAG+V+FS++G+   +  + V  V        
Sbjct: 258 AFASYMPMHNQVMKDGYTVVLVNCGTSLFAGIVVFSILGYREAKTGIPVTEVWTIRRVSG 317

Query: 372 ---------VDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTA 422
                    V  G GLAFI + + +  + +SPLW+ILFF+ML+ LG+DS+F  +E     
Sbjct: 318 FAYGGRGLRVGSGPGLAFITFSDAMLLMDVSPLWAILFFMMLILLGIDSEFGTLEAAIGP 377

Query: 423 I--LDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGE 480
           I  L+ FP  R  K  V   VAV   L GL  T+ +G Y  Q+ D Y+    +L+IA+ +
Sbjct: 378 IMELNLFPKVR--KELVTLGVAVILLLLGLCMTSGAGYYIFQMFDDYSVTIPLLVIALFQ 435

Query: 481 CILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILV 529
           CI +AW+YG ++F  DIQ M G++   WV  W   W+ I+P AL+ +L+
Sbjct: 436 CIGVAWVYGNDRFADDIQFMTGKRP--WVG-WMICWKYISPIALLVVLI 481



 Score =  111 bits (266), Expect = 7e-23
 Identities = 50/124 (40%), Positives = 71/124 (57%), Gaps = 3/124 (2%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           ER  W  + +F            NVWRFPYLC  NGGGAFL+P+ + ++I GLPL F+EL
Sbjct: 2   ERETWGHKAEFILATIGLAVGLGNVWRFPYLCQKNGGGAFLVPYIIFMLIEGLPLFFLEL 61

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
           S GQ      +  +    P   G+G   ++VS ++ LYY +IIAW  ++  +SF+S    
Sbjct: 62  SIGQRMRKSAINCWRDIHPCLFGIGVACLMVSLMLCLYYIVIIAWCCYFFFISFTS---D 118

Query: 145 LPWQ 148
           LPW+
Sbjct: 119 LPWK 122


>UniRef50_Q4RX19 Cluster: Transporter; n=1; Tetraodon
           nigroviridis|Rep: Transporter - Tetraodon nigroviridis
           (Green puffer)
          Length = 565

 Score =  273 bits (669), Expect = 1e-71
 Identities = 134/335 (40%), Positives = 190/335 (56%), Gaps = 13/335 (3%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           ERG W  + +F            NVWRFPYLCY NGGGAF +P+ +  V  G+P+ F+E 
Sbjct: 7   ERGQWNSKIEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFVPYVIFFVCCGIPVFFLET 66

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
           + GQ+ + G +  + K CPLF G+GY   ++ + + +YY +I+AW IFY+   F++   +
Sbjct: 67  ALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIVILAWAIFYLFNCFTT---E 123

Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPA 204
           LPW  C   W+T    +   +  C      +    C +     + NIT    T+    P 
Sbjct: 124 LPWAGCGHYWNTGSSNAPFVSHLC------FSAENCIDYYGENATNITNPNATS----PV 173

Query: 205 EEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264
            E++  +VL +S GIE  G +R  +AMCL  AW I + C+ KG +S+GKVVY TA FPYV
Sbjct: 174 IEFWERRVLKISDGIEHMGGVRWELAMCLALAWFICYFCIWKGPKSTGKVVYVTATFPYV 233

Query: 265 VLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSY 324
           +L++L  RGVTLPGA  GI FYL PD S+L++ QVW DA  QIFF+ +   G L  L SY
Sbjct: 234 MLLVLLIRGVTLPGAYDGIKFYLYPDISRLSDPQVWVDAGTQIFFSYAICLGCLTALGSY 293

Query: 325 NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGF 359
           N + NNCY    + + + I +S     V  S + F
Sbjct: 294 NAYDNNCYRYGGVFSTAYIYSSELCACVTVSPMVF 328



 Score =  121 bits (292), Expect = 5e-26
 Identities = 57/124 (45%), Positives = 87/124 (70%), Gaps = 3/124 (2%)

Query: 334 DSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPIS 393
           D +++   N  TSF AG  IFSV+GF+A+E NV ++ V + G GLAFI YP+ VT +P++
Sbjct: 337 DCIMLCCLNSGTSFLAGFAIFSVLGFMAYEQNVPIEAVAESGPGLAFIAYPKAVTMMPLA 396

Query: 394 PLWSILFFVMLLTLGLDSQFALMETVTTAILDRFP-NFRQ--KKGWVVFIVAVFGYLGGL 450
           PLW+ LFF+ML+ LGLDSQF  +E++ TA++D +P  FR+  ++  ++  ++V  +L GL
Sbjct: 397 PLWACLFFMMLIFLGLDSQFVCVESLVTAVVDLYPETFRRGYRRELLILGMSVVSFLIGL 456

Query: 451 IFTT 454
           I  T
Sbjct: 457 IMCT 460


>UniRef50_O45813 Cluster: Transporter; n=2; Caenorhabditis|Rep:
           Transporter - Caenorhabditis elegans
          Length = 1022

 Score =  269 bits (659), Expect = 2e-70
 Identities = 151/479 (31%), Positives = 254/479 (53%), Gaps = 32/479 (6%)

Query: 29  WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQ 88
           W  + DF            +  RFP   Y +GGG F IP+   L+  GLPL+F+ LS GQ
Sbjct: 160 WRTQKDFFLSCLGFMVGVGHTMRFPAKVYQHGGGVFFIPYLFSLIFFGLPLVFLHLSLGQ 219

Query: 89  YAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFY--QLP 146
           Y        + +  P+  G+G+ +V+++  V +YYN+I+AW I Y   S   +    +LP
Sbjct: 220 YTGQAANTAFQRLMPIGSGVGWALVVIAIPVAVYYNIIVAWAIHYFFQSAKGLLLGDELP 279

Query: 147 WQNCKAEWSTKH-CYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAE 205
           W+ C+ EW   + C        C   N    L  CFN + S    ITA           E
Sbjct: 280 WETCRDEWQLDNRC--------CNLHN----LHSCFNSTNS----ITA----------PE 313

Query: 206 EYFTNQVLGLSS-GIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264
            +F ++VL LS+ G    G ++  + + L AAW++VF  + KG+ S  + +  TA  PY+
Sbjct: 314 AFFHSEVLSLSTFGDFALGPLQSHLVLSLAAAWLLVFFGVFKGLGSIAQTMNVTATVPYL 373

Query: 265 VLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSY 324
           +L IL  RG++LPGA  G+ F  T D ++L   Q+W  AA Q+F+ L    G LI+++++
Sbjct: 374 LLSILLLRGISLPGANKGLTFLFTVDSTKLWKWQIWKSAAEQVFYELGIDAGPLISMAAF 433

Query: 325 NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQG-AGLAFIVY 383
           +++ NN Y DS+++ + +  TS  +G+VIFS +GF+A E N +V+ V+      L+F VY
Sbjct: 434 SRYRNNIYRDSVLLVIMDALTSCLSGMVIFSFVGFIASESNSNVNDVLKHDPLYLSFTVY 493

Query: 384 PEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFP-NFRQKKGWVVFIVA 442
           P V + +    LW+ LFF ML+   +D++FA +E + +A ++ F    +  +  ++  + 
Sbjct: 494 PGVTSFMYWGGLWATLFFGMLVLAAIDAEFAWLEMIASAFMNHFSMKNKAVENRLLAFLC 553

Query: 443 VFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMI 501
           + G+  GL      G++    ++   ANW+   +A+    ++ ++YG + +  DI  M+
Sbjct: 554 LAGFFLGLPLCAQGGIFVFHAIENLNANWNSFSLALLSVAIVCYVYGIDNYLTDISAML 612


>UniRef50_Q4SR96 Cluster: Transporter; n=4; cellular organisms|Rep:
           Transporter - Tetraodon nigroviridis (Green puffer)
          Length = 1013

 Score =  258 bits (632), Expect = 3e-67
 Identities = 135/314 (42%), Positives = 193/314 (61%), Gaps = 28/314 (8%)

Query: 244 LCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYL--TPDFSQLANAQVWG 301
           L K V++ G VVYFTA FPYVV++IL  RG TL GA  GI FY+    + +++ + QVW 
Sbjct: 289 LLKRVRNGGAVVYFTATFPYVVILILLIRGATLEGARDGIEFYIGSQSNLTKVLDVQVWK 348

Query: 302 DAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLA 361
           DAA Q F++LS  WGG++TLSSYN F NN + D+ +V ++N  TS  AG  IFS++G +A
Sbjct: 349 DAATQTFYSLSIGWGGVMTLSSYNNFHNNMFKDTFVVTLTNAGTSVVAGFAIFSILGHMA 408

Query: 362 HELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQF-ALMETVT 420
           H   + V  VV +G GLAFI YP+ +++LP+SPLWSILFF MLLT+GLDSQF  ++E +T
Sbjct: 409 HVYQMPVGEVVKEGFGLAFIAYPDALSKLPVSPLWSILFFFMLLTVGLDSQFTGIVEVLT 468

Query: 421 TAILDRFPNF-RQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIG 479
           T + D FP F   K+ WV     +  YL GL   + +G+YW+ L+D++ A+W +L + + 
Sbjct: 469 TCLTDAFPKFLSNKRIWVTVPTCLVLYLLGLPCVSRAGIYWVTLIDQFVASWVLLFLTLL 528

Query: 480 ECILIAWIY------------------------GAEKFCGDIQRMIGRQSKLWVYLWSAM 515
           E I + +IY                        G  +F  DI+ M+G++S L+   W A 
Sbjct: 529 EIIGVCYIYGKHSCLEAMAAAAAAVTFSPHASAGGNRFIEDIEMMLGKKSCLFWLWWRAC 588

Query: 516 WRIITPAALVFILV 529
           W  I+P  +V + V
Sbjct: 589 WFCISPCIIVRLKV 602



 Score =  251 bits (615), Expect = 4e-65
 Identities = 138/313 (44%), Positives = 197/313 (62%), Gaps = 29/313 (9%)

Query: 107 GLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEAD 166
           G+G+ MV+VS +V +YYN+IIA++++Y+  SF S    LPW  C        C S   A 
Sbjct: 685 GVGFSMVMVSMLVAVYYNVIIAYSLYYLFASFQS---PLPWAACSG------CSSASTA- 734

Query: 167 ECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIR 226
                            S +VS  + A       + P+E Y+ + VL  SSG+++TG + 
Sbjct: 735 -----------------SCNVSGVLVANHTCPPGQSPSEHYWDHVVLQRSSGLDDTGPVV 777

Query: 227 LGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFY 286
             +A+CL  + V+V   L +G++SSGKVVYFTA FPYVV++IL  RGVTL GA  G+ F+
Sbjct: 778 WHLAVCLGLSSVLVAGILSRGIKSSGKVVYFTATFPYVVILILLVRGVTLEGAGEGLKFF 837

Query: 287 L--TPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIA 344
           +    ++S+LA  +VW DAA Q FF LS   GGL TLSSY++F  N ++DS++V   +  
Sbjct: 838 IGSKSNWSKLAEVKVWNDAAAQTFFTLSIGMGGLFTLSSYSEFHTNIFLDSVVVVFVSYG 897

Query: 345 TSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVML 404
           TS  AG+ IFS++G +AH     +++VV +G GLAFIVYPE +T+LPIS LW +LFFVML
Sbjct: 898 TSVLAGVAIFSILGHMAHVYKRPIEKVVKEGFGLAFIVYPEALTQLPISALWCVLFFVML 957

Query: 405 LTLGLDSQFALME 417
           + + +DSQF L+E
Sbjct: 958 IVISVDSQFTLIE 970



 Score =  159 bits (387), Expect = 2e-37
 Identities = 91/245 (37%), Positives = 138/245 (56%), Gaps = 21/245 (8%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           ERG WT + ++            N+WRFPYL Y NGGGAFLIP+ VMLV+ G+PL F+E 
Sbjct: 1   ERGTWTSKKEYILSTIGYAVGLGNIWRFPYLAYKNGGGAFLIPYFVMLVVTGIPLFFLES 60

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
           +FGQ+ + GP+ V+ +  P+ +G+G GMV+V+ IV +YYN+I+A++++YM  SF S    
Sbjct: 61  AFGQFCSQGPINVW-RAVPILQGVGVGMVMVTLIVSIYYNVILAYSLYYMFASFQS---P 116

Query: 145 LPWQNCKAEWSTKHCYSYEE------------ADECEAQNGTYY--LRQCFNQSYSVSHN 190
           LPW      W+  +C S                DE E  +   +  L    N S  ++ N
Sbjct: 117 LPWSGF-FSWAEGNCSSTPAGALMVVTVALPLCDEGEKPSRCLFFALSASCNGSGVLAAN 175

Query: 191 ITALAKT--ALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGV 248
            T    T  +  + P+E Y+    L  SSG++ETG +   +A+CLL + ++V   L KG+
Sbjct: 176 GTQENSTCPSSVQSPSELYWDCVALQRSSGLDETGPVVWHLALCLLLSSILVCAALIKGI 235

Query: 249 QSSGK 253
           ++ GK
Sbjct: 236 KAEGK 240



 Score = 44.8 bits (101), Expect = 0.007
 Identities = 17/52 (32%), Positives = 28/52 (53%)

Query: 24  PERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIA 75
           PER +W+ R ++            N+W+FP+L Y+NGGG       V +++A
Sbjct: 647 PERLHWSSRAEYMLSMVGFAIGLGNIWKFPWLAYSNGGGVGFSMVMVSMLVA 698


>UniRef50_A6LMJ8 Cluster: Sodium:neurotransmitter symporter
           precursor; n=1; Thermosipho melanesiensis BI429|Rep:
           Sodium:neurotransmitter symporter precursor -
           Thermosipho melanesiensis BI429
          Length = 498

 Score =  254 bits (621), Expect = 7e-66
 Identities = 135/354 (38%), Positives = 212/354 (59%), Gaps = 14/354 (3%)

Query: 206 EYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVV 265
           ++F N+ L +S+G  E G IR  + + L   W+ ++  L KG  S GK V +T   P ++
Sbjct: 125 KFFFNEFLQVSNGPSELGSIRWPIVIGLALTWLWIYFILRKGTTSVGKTVAWTVPLPVIL 184

Query: 266 LVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYN 325
           L+IL  RG+TL GA  G+ F   P+F++LA  +VW +A  QIFF LS A+G +I   SYN
Sbjct: 185 LIILGIRGITLEGAAQGLNFLFQPNFAKLAEPRVWANAFGQIFFTLSLAFGIMIAYGSYN 244

Query: 326 KFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPE 385
           K   +   +++I A+ N ATSF AG+ +FSV+G++A ++N  +D VV  G GLAF+VYP+
Sbjct: 245 KKEEDIANNAIITALGNSATSFLAGIAVFSVLGYMALQINSPIDEVVSGGIGLAFVVYPQ 304

Query: 386 VVTRLP----ISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIV 441
            ++  P    +  +  + FFVMLLTLG+DS F+L+E V  A  D+F  F ++   + F  
Sbjct: 305 AISLFPGGVIVQSIIGLAFFVMLLTLGIDSAFSLVEAVEAAASDKF-KFNKRSFLIGF-- 361

Query: 442 AVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMI 501
           ++FG+L GL+++T  G+YWL ++D + + +++LI+ I E I+I W+  AEK    ++  I
Sbjct: 362 SIFGFLVGLLYSTQGGLYWLDIIDHFLSIYALLIVGILESIIIGWVLDAEK----LRNYI 417

Query: 502 GRQSKLWVYLW-SAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGW 554
            + S++ +  W     R I P +L+ IL     +     YG   YP WA   G+
Sbjct: 418 NKVSEVKIGKWFDISLRYIIPGSLIIILGLTLYDEIKNPYGG--YPTWALLTGF 469



 Score = 86.2 bits (204), Expect = 2e-15
 Identities = 39/113 (34%), Positives = 58/113 (51%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           R  W  R+ F            N WRFPY+ Y+NGGGAF +P+ + L +AG+PL+  E +
Sbjct: 3   RQKWGSRWAFVLAAIGSAAGLGNAWRFPYMAYSNGGGAFYVPYFIALFLAGIPLLMAEFA 62

Query: 86  FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSF 138
            GQ    G      K       +G+  VI  +++  YYN+I+A+   Y+  SF
Sbjct: 63  IGQGFQSGAPRSLAKIKKGAEFIGWWAVITGALITFYYNVIMAYIFNYLYYSF 115


>UniRef50_A1ZBC7 Cluster: Transporter; n=5; Diptera|Rep: Transporter
           - Drosophila melanogaster (Fruit fly)
          Length = 561

 Score =  250 bits (612), Expect = 9e-65
 Identities = 124/328 (37%), Positives = 189/328 (57%), Gaps = 7/328 (2%)

Query: 229 MAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLT 288
           +  CL  AW+++   L +G++SSGK  YF  +FPYVVL+IL  R VTLPGAI GI+++  
Sbjct: 184 LVACLAIAWLVIGGVLIRGIKSSGKAAYFLGVFPYVVLLILLLRAVTLPGAIDGIIYFFK 243

Query: 289 PDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFF 348
           P + +L N  VW  A  Q+FF+L+  +G LIT +SYN F+ N Y D +I+   +  +S  
Sbjct: 244 PQWRELLNPLVWYAAVTQVFFSLAICFGTLITYASYNNFNRNVYNDIVIITTMDSCSSII 303

Query: 349 AGLVIFSVIGFLAHEL-NVSVDRVVDQGAGLAFIVYPEVVTRLPISP-LWSILFFVMLLT 406
           AG + F ++G LA E  N  +  VV  GAGLAFI YPE + +    P ++++LFF+ML  
Sbjct: 304 AGCITFGILGNLARETGNPDIGSVVKGGAGLAFISYPEAIAKFEYVPQMFAVLFFLMLFV 363

Query: 407 LGLDSQFALMETVTTAILDRFPNFRQKKGW-VVFIVAVFGYLGGLIFTTNSGMYWLQLMD 465
           LG+ S   +   +   I D+F   R    W +   + V G+   +++ T  G + L L+D
Sbjct: 364 LGIGSTVGMGSCILRVIRDQF-GLRSPPIWKLASGLTVLGFSVSIVYMTPGGQFILNLVD 422

Query: 466 KYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALV 525
            Y  +++ LI+AIGE + +AWIYG  +FC DI+ M+G ++    + W   WR ITP  + 
Sbjct: 423 FYGVSFTALILAIGELVAVAWIYGVNRFCEDIKFMMGIETG---WYWRLCWRFITPGLMT 479

Query: 526 FILVFNWIEYKPASYGHYVYPMWADAVG 553
            +L++  ++     Y    YP  A   G
Sbjct: 480 AVLIYMLLDMSALEYKGVGYPTLAHVFG 507



 Score =  104 bits (249), Expect = 8e-21
 Identities = 47/145 (32%), Positives = 77/145 (53%), Gaps = 8/145 (5%)

Query: 12  EKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVM 71
           +KS+ P  +  E     W    +F            N+WRFPY+ + NGGG F+IP+ + 
Sbjct: 8   KKSEKPAEKPAE----QWGNGLEFLFSCISLSVGLGNIWRFPYIAFQNGGGTFVIPYLIA 63

Query: 72  LVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTI 131
           L++ G P+ ++E+S GQ+   G V  ++   PL +G+  G V+ ++  + YY+ I+A T+
Sbjct: 64  LLVIGRPVYYLEISLGQFTGRGVVKAFD-MAPLLKGVALGQVLATAASITYYSSIMALTL 122

Query: 132 FYMTVSFSSIFYQLPWQNCKAEWST 156
            +   SF S   +LPW  C   W T
Sbjct: 123 RFWLASFGS---ELPWSRCWESWGT 144


>UniRef50_UPI000066095C Cluster: Homolog of Brachydanio rerio
           "Glycine transporter 2.; n=1; Takifugu rubripes|Rep:
           Homolog of Brachydanio rerio "Glycine transporter 2. -
           Takifugu rubripes
          Length = 416

 Score =  246 bits (603), Expect = 1e-63
 Identities = 122/321 (38%), Positives = 194/321 (60%), Gaps = 14/321 (4%)

Query: 208 FTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLV 267
           F  ++L  +SG+EE G ++  + +CLL AW +V+LC+ KGV+S+GKVVYFT  FPY++L+
Sbjct: 5   FRYRMLQQTSGLEEMGTVQWELCLCLLLAWTLVYLCIFKGVKSTGKVVYFTVTFPYIILI 64

Query: 268 ILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKF 327
            L      LPGA+ GI F++ P + +L   +VW +AA QIF ++  ++G L+ +SSYN  
Sbjct: 65  ALLIHYAQLPGALEGIKFFILPQWEKLRLVEVWVNAAAQIFNSIGLSYGSLLAMSSYNS- 123

Query: 328 SNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVV 387
                +D+L +++ N  TS  AG VIFS  G++++   + V  +   G GL FIVYP+ +
Sbjct: 124 -----LDTLTISIVNSLTSILAGFVIFSAFGYMSYLQGIPVTDLPVDGPGLVFIVYPQAL 178

Query: 388 TRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFP----NFRQKKGWVVFIVAV 443
             +P + LWS+LFF+MLL LGLDS+FA +E + T++LD F      F ++K   V +V  
Sbjct: 179 ANIP-AQLWSVLFFLMLLCLGLDSEFAGVEVIVTSLLDGFHYDLIRFLRRKEVFVLVVCG 237

Query: 444 FGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGR 503
             +L G+      G+Y  QL+D Y A  S+L ++  E I + WIYG  +    ++ M G+
Sbjct: 238 AQFLFGIPCVLQGGIYIFQLLDYYTAIVSLLFVSFFEVIAVCWIYGVSRLSNILEEMTGK 297

Query: 504 QSKLWVYLWSAMWRIITPAAL 524
           +  ++   +   W +I P  +
Sbjct: 298 RPNIF---FRTCWLVIAPVLI 315



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 16/34 (47%), Positives = 24/34 (70%)

Query: 521 PAALVFILVFNWIEYKPASYGHYVYPMWADAVGW 554
           P + + IL+F+ I++KPA Y  YV+P WA  +GW
Sbjct: 348 PGSALVILIFSIIQFKPARYEDYVFPPWAQGIGW 381


>UniRef50_O18288 Cluster: Transporter; n=1; Caenorhabditis
           elegans|Rep: Transporter - Caenorhabditis elegans
          Length = 635

 Score =  238 bits (582), Expect = 4e-61
 Identities = 131/367 (35%), Positives = 200/367 (54%), Gaps = 22/367 (5%)

Query: 210 NQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVIL 269
           N V+  S+G  +   I + M   +   WVI  + L +G+++ GK+ Y+T L PY +++ L
Sbjct: 185 NFVVKPSTGFTDFNSINVPMLAAVAVCWVIAIISLIRGMKAIGKLSYYTVLLPYAIIIAL 244

Query: 270 FFRGVTLPGAITGI--LFYLTP------DFSQLANAQVWGDAAVQIFFALSPAWGGLITL 321
             RG+TL GA TG+  LF+  P      DF+ L +  VW  A +Q+ F+LS   GGL+ +
Sbjct: 245 MIRGLTLEGASTGLHFLFWGKPNEYGHYDFAGLYDPDVWIAALMQMCFSLSIGQGGLMNI 304

Query: 322 SSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSV------DRVVDQG 375
            SYNK + N Y D+ +V + +   S   G  +FS +GFLA + N+S+      + VV +G
Sbjct: 305 GSYNKKTYNWYRDAYLVVLCDTLMSLLGGTAVFSTLGFLAEQRNISISNPKGFNEVVQEG 364

Query: 376 AGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKG 435
             LAFIVY E + ++P   LW  LFFVML  LG+ ++  ++ETV + + DRF   RQ + 
Sbjct: 365 HALAFIVYTEAIAQMPYPFLWYALFFVMLFLLGISTEIVIIETVCSCLADRFHYLRQHRW 424

Query: 436 WVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCG 495
             V  V+   +L GL+ T+++G YW  L D+Y+A  S  I     C+ + W YG + F  
Sbjct: 425 ITVVTVSTTFFLLGLVMTSDAGFYWFDLYDEYSAGVSATIGTAIMCLTVCWCYGLDNFRA 484

Query: 496 DIQRMIGR-QSKL------WVYLWSAMWRIITP-AALVFILVFNWIEYKPASYGHYVYPM 547
           DI+ M    +S+L        Y+W+ +WR +TP   LV +  + W +  P       YP 
Sbjct: 485 DIREMWEEPESRLDKYLGPGAYVWTIVWRFVTPICCLVIMFAWIWDKKYPFKGDSKKYPP 544

Query: 548 WADAVGW 554
             DA GW
Sbjct: 545 VFDAFGW 551



 Score = 86.6 bits (205), Expect = 2e-15
 Identities = 33/87 (37%), Positives = 55/87 (63%)

Query: 48  NVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRG 107
           N+WRFP   Y NGG +FLI + V  ++  +P + ME + GQYAA  P A + +  P+  G
Sbjct: 87  NIWRFPTTAYKNGGLSFLIAYVVCGILFAVPAIHMEFALGQYAAKSPPAAFRRMMPILEG 146

Query: 108 LGYGMVIVSSIVMLYYNLIIAWTIFYM 134
           +G+   +V +I+ +YY ++I+W + Y+
Sbjct: 147 VGWMTCLVGAIIGVYYMIVISWIVLYL 173


>UniRef50_Q2AHK9 Cluster: Transporter; n=1; Halothermothrix orenii H
           168|Rep: Transporter - Halothermothrix orenii H 168
          Length = 350

 Score =  237 bits (579), Expect = 9e-61
 Identities = 124/313 (39%), Positives = 186/313 (59%), Gaps = 12/313 (3%)

Query: 236 AWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLA 295
           +W+ ++L L KG +S GKVV +T + P V+L+IL  R VTLPGAI G+ +YL PDF++L 
Sbjct: 2   SWIAIYLILRKGTESVGKVVPYTVILPVVLLLILIIRSVTLPGAIEGLNYYLKPDFTKLL 61

Query: 296 NAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFS 355
           +  VW DA  Q+FF LS   G +I  +SY   +++   ++LI   +N   SF AG+ +F 
Sbjct: 62  DIGVWIDAYTQVFFTLSLGMGIMIAYASYMPKNSDVVNNALITVFANSGVSFMAGIAVFG 121

Query: 356 VIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPL----WSILFFVMLLTLGLDS 411
            +G++A E  V++  VV  G  LAF+ YP  +  LP  P+    + ++FFV LLTLG+DS
Sbjct: 122 TLGYMAQEQGVAIADVVADGVILAFVTYPNAINMLPGGPIVAGFFGVVFFVTLLTLGIDS 181

Query: 412 QFALMETVTTAILDRFP-NFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAAN 470
            F+L+E+    I+D++  N R+   WVV ++ V     GLIF T +G+YWL L+D Y   
Sbjct: 182 AFSLVESNVAGIVDKWGFNRRKTTFWVVVLLLV----TGLIFATRAGLYWLDLIDHYVNT 237

Query: 471 WSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVF 530
           + +L+  + E + I W Y AEK       +   Q   W   W+ M ++ITP  LV++ VF
Sbjct: 238 YGLLLGGLLEALAIGWFYNAEKLRNYFNPISEYQFGKW---WNIMVQVITPIILVYLFVF 294

Query: 531 NWIEYKPASYGHY 543
           N  +   A+YG Y
Sbjct: 295 NLSKDIGANYGGY 307


>UniRef50_UPI0000DC2074 Cluster: UPI0000DC2074 related cluster; n=1;
           Rattus norvegicus|Rep: UPI0000DC2074 UniRef100 entry -
           Rattus norvegicus
          Length = 491

 Score =  236 bits (578), Expect = 1e-60
 Identities = 138/486 (28%), Positives = 248/486 (51%), Gaps = 33/486 (6%)

Query: 48  NVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRG 107
           + WRFPYLC+ NGGG+FL+ + ++L++ G+PLM+ME+  GQ+  +  +  +    P   G
Sbjct: 17  STWRFPYLCHQNGGGSFLLMYLILLLLLGIPLMYMEMVIGQWLRVDNIRAWKHLVPWLSG 76

Query: 108 LGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADE 167
           +GY  ++  ++V+LY + +++W++FY+  SF    Y  PW+NC          S EE D 
Sbjct: 77  VGYSSMLACALVILYNSALVSWSLFYLGQSFD---YPTPWENCPLV--KNFSTSGEERD- 130

Query: 168 CEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIR- 226
                G      C N S              LR  P + ++ + VL  S  IEE  E+  
Sbjct: 131 --GGGG------CKNIS-------------CLRTEPHQFFWYHTVLRASDQIEEGIEVLV 169

Query: 227 LGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFY 286
           L + +CL A W  +++ +   ++ S  ++ F+ LFP V+L   F     + G    +   
Sbjct: 170 LNVTLCLFATWFFLYITMVTRIKISVLMMIFSILFPNVLLFCFFTHIFFVKGVRDSLKRL 229

Query: 287 LTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATS 346
           +T + S LA+   W  A   + ++L    G +IT SSY     N    +  VA+ N+ TS
Sbjct: 230 VTTELSILASLDAWRQAGGHVLYSLGLGMGTIITFSSYQTRGENYIKWASFVAMVNLMTS 289

Query: 347 FFAGLVIFSVIGF-LAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLL 405
             +  VIF ++GF + +     V+R   +G GLA++ + + +T  P S  W+I+FF+ L+
Sbjct: 290 LLSSSVIFLMLGFWIENSGTPCVERQFMEGPGLAYVAFSQAITLFPGSSFWAIIFFMSLV 349

Query: 406 TLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMD 465
            +GL +   L+E +  ++        +    V  I+ + G+LG L+F++  G Y + L D
Sbjct: 350 IMGLGTMTTLVEGIALSLQKSISTLEKHPKLVPVIICLGGFLGSLVFSSRPGSYVVFLFD 409

Query: 466 KYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIIT-PAAL 524
            +     +++I   + + +AW+YG ++F  ++   +GR   +W   ++ +W  +T P  L
Sbjct: 410 DHLVPMVLIMIVAFQNLSLAWVYGIKRFRAEMFGQLGR--LVWA-PFTFLWSYVTLPTLL 466

Query: 525 VFILVF 530
           V + ++
Sbjct: 467 VLLTIY 472


>UniRef50_Q8IRU1 Cluster: Transporter; n=2; Diptera|Rep: Transporter
           - Drosophila melanogaster (Fruit fly)
          Length = 682

 Score =  231 bits (565), Expect = 4e-59
 Identities = 133/385 (34%), Positives = 200/385 (51%), Gaps = 41/385 (10%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           ER +W  +  F            NVWRFPYL   NGGGAFL+P+ +ML I G+P+ ++EL
Sbjct: 53  ERESWDSKIMFLLATIGYAVGLGNVWRFPYLAQKNGGGAFLVPYFIMLCIQGIPIFYLEL 112

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
           + GQ    G + V+++  P   G+G    +VS IV           ++Y T+    + Y 
Sbjct: 113 AIGQRLRKGAIGVWSQVSPYLGGIGISSAVVSYIV----------ALYYNTIIAWCLIYL 162

Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPA 204
           L        W+           +C  +           ++++  H    +A +     P 
Sbjct: 163 LHSFESPLPWA-----------DCPTR---------LYKNFTYDHEPECVASS-----PT 197

Query: 205 EEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264
           + Y+    L  S  ++        MA+ L+ +W +V++C+ +G+ SSGK+VY TA+FPYV
Sbjct: 198 QFYWYRTTLQCSESVDMPENFNYHMAIALIVSWFLVYICMVQGITSSGKIVYMTAIFPYV 257

Query: 265 VLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSY 324
           VL+I FFRG+TL GA  G+    TP +  L +  VW +A  QIFF+L  A+GGLI  SSY
Sbjct: 258 VLIIFFFRGITLKGAADGVAHLFTPRWETLLDPVVWLEAGTQIFFSLGLAFGGLIAFSSY 317

Query: 325 NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYP 384
           N  +NNCY D+++V+++N  TS FAG+V+FSVIGF A     + DR  ++  GL   V  
Sbjct: 318 NPANNNCYRDAILVSLTNCGTSMFAGVVVFSVIGFKA---TATFDRCTEERNGL---VAQ 371

Query: 385 EVVTRLPISPLWSILFFVMLLTLGL 409
                LP+  L + L  V  L + L
Sbjct: 372 NKTHNLPVCDLQTELANVSSLAICL 396



 Score =  130 bits (314), Expect = 1e-28
 Identities = 69/183 (37%), Positives = 108/183 (59%), Gaps = 10/183 (5%)

Query: 375 GAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDR--FPNFRQ 432
           G GLAFI++ E + + P + LW++LFF+ML TLG+DSQF  +E V T+++D   FPN   
Sbjct: 412 GTGLAFIIFTEAINQFPGAQLWAVLFFLMLFTLGIDSQFGTLEGVVTSLVDMKLFPNL-- 469

Query: 433 KKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEK 492
            K ++V  +        + F   +G Y  QLMD +A N+ +LIIA+ EC+ I++IYG  +
Sbjct: 470 PKEYIVGALCFSCCTISMCFANGAGSYIFQLMDSFAGNFPLLIIALFECLSISYIYGVRR 529

Query: 493 FCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAV 552
           F  DI+ M G +     + W   W+ ++P A+V IL+ ++  Y+  + G   YP W  + 
Sbjct: 530 FSDDIEMMTGSRPN---FYWMFCWKYLSPCAMVTILLASF--YQLLTEGS-SYPAWIGSK 583

Query: 553 GWT 555
           G T
Sbjct: 584 GAT 586


>UniRef50_Q2QAU1 Cluster: Transporter; n=2; Didelphinae|Rep:
           Transporter - Didelphis marsupialis virginiana (North
           American opossum)
          Length = 618

 Score =  231 bits (564), Expect = 6e-59
 Identities = 124/339 (36%), Positives = 190/339 (56%), Gaps = 38/339 (11%)

Query: 23  EPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFM 82
           E ER  W  +F +            N+WRFPYLC   GGGAFLIP+ + L+  G+PL  +
Sbjct: 16  EDERPKWDNKFQYILSCVGFAVGLGNIWRFPYLCQTYGGGAFLIPYFIALIFEGIPLFHI 75

Query: 83  ELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIF 142
           EL+ GQ    G + V++   P  +G+G G + VS +V          +++Y T+    ++
Sbjct: 76  ELAIGQRLRTGSIGVWSTISPYLKGVGIGCLFVSFLV----------SLYYNTILMWVMW 125

Query: 143 YQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRP 202
           Y L        WS+  C   E        N T  + +C   S +V++             
Sbjct: 126 YFLNSFQSPLPWSS--CPPNE--------NRTGLIEEC-QSSNAVNY------------- 161

Query: 203 PAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFP 262
               ++  + L +++ I E+G ++  + MCL+A W+IV++C+ +G++++GK +YFTALFP
Sbjct: 162 ----FWYRKTLNITTDINESGTLQWRLIMCLVACWMIVYICVIRGIETTGKAIYFTALFP 217

Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322
           Y+VL I   RG+TLPGA  G+++  TP+ S L N QVW DAA QIFF+LS A+GG I  S
Sbjct: 218 YLVLTIFLIRGLTLPGATEGLIYLFTPNMSILQNPQVWLDAATQIFFSLSLAFGGHIAFS 277

Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLA 361
           SYN   N+C  D++ +A+ N  TS +A + +FSV+GF A
Sbjct: 278 SYNPPKNDCEKDAVTIALVNSMTSLYASVAVFSVLGFKA 316



 Score =  130 bits (314), Expect = 1e-28
 Identities = 66/156 (42%), Positives = 95/156 (60%), Gaps = 4/156 (2%)

Query: 375 GAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQ-K 433
           G GLAFIV+ E +  +P SP W++LFF ML +LGL S F  ME V T ILD     R   
Sbjct: 382 GTGLAFIVFTEAIVHMPGSPGWAVLFFGMLFSLGLTSMFGNMEGVLTPILDLQILPRSVP 441

Query: 434 KGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKF 493
           K ++  ++ +   L  L FT  SG YWL++ DKYAA+ ++L+ A  E I + ++YG ++F
Sbjct: 442 KEFITGVICLVCCLCALCFTLQSGSYWLEIFDKYAASLNLLVFAFFEVIGVIYVYGLKRF 501

Query: 494 CGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILV 529
           C D++ M GR+  L+   W   W+II+P  L+ I V
Sbjct: 502 CDDVEWMTGRRPNLY---WQVAWKIISPLLLLIIFV 534


>UniRef50_A1I9V5 Cluster: Sodium-and chloride-dependent transporter;
           n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep:
           Sodium-and chloride-dependent transporter - Candidatus
           Desulfococcus oleovorans Hxd3
          Length = 499

 Score =  228 bits (558), Expect = 3e-58
 Identities = 121/341 (35%), Positives = 194/341 (56%), Gaps = 7/341 (2%)

Query: 204 AEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPY 263
           ++ +F   +L +S G  + G I   +   L+  WV+++  +  G+   GKV+ FT   P 
Sbjct: 128 SKAHFFTDILHISEGPWQFGTIYPNLLWGLVTTWVVIWAIIRSGLSGIGKVLLFTVPLPV 187

Query: 264 VVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSS 323
           ++++IL  RG+TL G+ TG+  YLTPD+ +L +  VW  A  QIFF+LS  +G +I  +S
Sbjct: 188 ILVLILLVRGLTLEGSATGLNHYLTPDWGRLTDYHVWLAAYGQIFFSLSVGFGTMIAYAS 247

Query: 324 YNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVY 383
           +          + I + SN   SF AGL +FSV+G+ A   NV +  V   G GLAFIVY
Sbjct: 248 FMPEDTELPNSAAITSFSNCCFSFLAGLAVFSVLGYFAVATNVPMTEVSQAGPGLAFIVY 307

Query: 384 PEVVTRLPI-SPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVA 442
           P  + +LP+    +  LF + LL LG+DS F+L+ETV+ A+ D+F   R        I A
Sbjct: 308 PAALAKLPVYVTFFGALFLITLLLLGIDSAFSLLETVSAALSDKFGITRSVS---TTITA 364

Query: 443 VFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIG 502
           VF +L GL   T +G+YWL +MD +  ++++  +AI EC+ + WI GA+ F  ++ R   
Sbjct: 365 VFSFLAGLPLATGAGIYWLDIMDHFIMSYAITTVAIVECLAVGWILGAKNFAAEVNRT-- 422

Query: 503 RQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHY 543
            + K+   ++S + R +TPA L + ++  +++   A Y  Y
Sbjct: 423 AEIKIGP-IFSFIIRFLTPAILGYSVIRTFVDEMQAPYEGY 462



 Score = 78.6 bits (185), Expect = 5e-13
 Identities = 36/113 (31%), Positives = 55/113 (48%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           ER +W  R  F            N+WRFPY+   NGGGAFLIP+   L+ AG+PLM +E 
Sbjct: 3   EREHWKNRSIFIMAAVGSAIGLGNMWRFPYIAAQNGGGAFLIPYMTALLTAGIPLMIIEY 62

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVS 137
             G            K     R +G+  ++ +  + +YY +++ WT  ++  S
Sbjct: 63  GLGIRTQGSAHIALGKIRKPLRFIGWMAILCALFINIYYCIVLGWTWNFLLAS 115


>UniRef50_Q9U2E3 Cluster: Transporter; n=1; Caenorhabditis
           elegans|Rep: Transporter - Caenorhabditis elegans
          Length = 600

 Score =  227 bits (554), Expect = 9e-58
 Identities = 114/312 (36%), Positives = 180/312 (57%), Gaps = 13/312 (4%)

Query: 253 KVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLT-PDFSQLANAQVWGDAAVQIFFAL 311
           K+ Y T + PY+++++L  RGVTL GA  G+ ++L   D+  L N + W  A  Q+ F+L
Sbjct: 213 KISYVTVILPYILIIVLLIRGVTLEGAGDGLKYFLARTDWVALYNFKTWSAALTQLCFSL 272

Query: 312 SPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRV 371
           S  +G L+  +SYNK ++ C+ D++ + + + A S   G  +FS +G+LA E  V+VD+V
Sbjct: 273 SIGFGVLMNTASYNKQNHRCFRDAIFLIIGDTAMSLIGGAAVFSTLGYLARERGVTVDKV 332

Query: 372 VDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFR 431
           V  G  LAFI YP+ + ++P   LWS LFF ML  LG+ +   ++E + T + D+FP  R
Sbjct: 333 VTDGTTLAFIAYPDAMNQMPFPGLWSFLFFFMLFLLGISTLLVIVEVMCTCLCDKFPRLR 392

Query: 432 QKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAE 491
           +K+ +VV  V    +L G+I TT++G+YW  L D+Y + +  LI A   CI+I++IYG  
Sbjct: 393 EKRVFVVIGVCFLLFLCGVILTTDAGIYWFALFDEYGSGFGALISATSMCIIISYIYGMR 452

Query: 492 KFCGDIQRMIGRQSKLW-VY-----LWSAMWRIITP---AALVFILVFNWIEYKPASYGH 542
            F  DI  M+GR +++  ++      +   W  I P     L+F+       +K  S   
Sbjct: 453 NFRADIASMLGRGTRISNIFGHNSPYYGFNWMFIMPIFGCVLIFLTANRGYPFKGES--- 509

Query: 543 YVYPMWADAVGW 554
            VYP+  D VGW
Sbjct: 510 AVYPVVFDIVGW 521



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 35/94 (37%), Positives = 50/94 (53%), Gaps = 5/94 (5%)

Query: 48  NVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRG 107
           N+WRFP   Y NGG  FLIP+    ++ GLP +++E + GQY    P  VY +  P   G
Sbjct: 119 NIWRFPSRAYENGGSVFLIPYITCALLFGLPGVYLEFAMGQYQGRSPPFVYRRIMPALEG 178

Query: 108 LGY---GMVIVSSIVMLYYNLIIAWTIFYMTVSF 138
            G+     ++  S  +L  N  I W IF + +SF
Sbjct: 179 FGWVAANYIVKPSKGLLDIN-SINWPIF-IAMSF 210


>UniRef50_Q8MZ19 Cluster: Transporter; n=7; Endopterygota|Rep:
           Transporter - Drosophila melanogaster (Fruit fly)
          Length = 675

 Score =  227 bits (554), Expect = 9e-58
 Identities = 130/350 (37%), Positives = 180/350 (51%), Gaps = 42/350 (12%)

Query: 23  EPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFM 82
           EPER  W+G+  F            N+WRFPYLC  NGGGAFLIPF VML++ G+PL  +
Sbjct: 52  EPERAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFLIPFMVMLILEGIPLFLI 111

Query: 83  ELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIF 142
           EL  GQ   LG + V+N   P   G+G    I S IV L+        ++Y  +     F
Sbjct: 112 ELGIGQRMRLGALGVWNTIHPWLGGIG----ISSCIVTLFV------ALYYNVIITWVFF 161

Query: 143 YQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRP 202
           Y          WS+           C      + L +C   S +                
Sbjct: 162 YLFNSFRYPLPWSS-----------CPLNGTGFELEECAKSSETTY-------------- 196

Query: 203 PAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFP 262
               ++    L  +  ++E G ++  + +CL+ +W IVF  + KG+QSSGKVVYFT+LFP
Sbjct: 197 ----FWYRTTLDAAPSMDEPGGLKWWIVLCLMLSWTIVFFIVMKGIQSSGKVVYFTSLFP 252

Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322
           Y+VL I F RG+TL GA  G++   TP   +L    VW DAA Q+F++   A+G LI   
Sbjct: 253 YIVLTIFFIRGITLRGAGAGLMHMYTPKVEKLLEPTVWLDAATQVFYSFGLAFGSLIAFG 312

Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVV 372
           SYN   NNC  D L+V+V N  T+ +A +VIF+++GF A    V+VDR V
Sbjct: 313 SYNTPKNNCVRDVLLVSVCNAVTAIYASVVIFAILGFKA---TVNVDRCV 359



 Score =  126 bits (304), Expect = 2e-27
 Identities = 68/171 (39%), Positives = 102/171 (59%), Gaps = 10/171 (5%)

Query: 360 LAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETV 419
           LAHEL+ + +     G GLAFIV+ + +  LP +P W++LFF MLL+LGL SQ  ++E +
Sbjct: 402 LAHELDNAAE-----GTGLAFIVFTQAIVELPGAPFWAVLFFTMLLSLGLGSQIGILEGM 456

Query: 420 TTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIG 479
              + D     R KK  V  +V +F ++ G IF T +G YWL++ D +A    ++++A+ 
Sbjct: 457 LCTLFDIDIIKRVKKQHVTGVVCLFCFIVGFIFCTGAGEYWLKMFDSFAGTIGLVVVALM 516

Query: 480 ECILIAWIYGAEKFCGDIQRMIG-RQSKLWVYLWSAMWRIITPAALVFILV 529
           E I + +IYG E+F  DI +M G R  + W   W+  WR I P  +V ILV
Sbjct: 517 EMIAVIFIYGHERFTEDIFQMTGYRPGRYW--QWT--WRYIGPVIMVCILV 563


>UniRef50_UPI0000ECA0A4 Cluster: Orphan sodium- and
           chloride-dependent neurotransmitter transporter NTT4
           (Solute carrier family 6 member 17).; n=1; Gallus
           gallus|Rep: Orphan sodium- and chloride-dependent
           neurotransmitter transporter NTT4 (Solute carrier family
           6 member 17). - Gallus gallus
          Length = 439

 Score =  225 bits (551), Expect = 2e-57
 Identities = 109/249 (43%), Positives = 156/249 (62%), Gaps = 5/249 (2%)

Query: 252 GKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFAL 311
           G V+YF++LFPYVVLV    RG+ L GA+ GI+   TP   ++ + QVW +AA Q+FFAL
Sbjct: 196 GVVMYFSSLFPYVVLVCFLVRGLLLRGAVDGIMHMFTPKLDKMLDPQVWREAATQVFFAL 255

Query: 312 SPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRV 371
              +GG+I  SSYNK  NNC+ D+ +V+  N  TS  A LV+F+V+GF A+ +N     V
Sbjct: 256 GLGFGGVIAFSSYNKQDNNCHFDATLVSFINFFTSVLATLVVFAVLGFKANIMNEKC--V 313

Query: 372 VDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFR 431
           V+QG GLAFI + E +T  P SP WS++FF+ML+ LGL S    M  +TT I+D    F+
Sbjct: 314 VEQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMSGITTPIID---TFK 370

Query: 432 QKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAE 491
            +K        +F ++ GLIF   SG Y++ + D Y+A   + ++ I E I +AWIYG +
Sbjct: 371 VRKEVFTVGCCIFAFVVGLIFVQRSGNYFVTMFDDYSATLPLTVVVILENIAVAWIYGTK 430

Query: 492 KFCGDIQRM 500
           KF  ++  M
Sbjct: 431 KFMQELTEM 439



 Score =  133 bits (322), Expect = 1e-29
 Identities = 60/132 (45%), Positives = 77/132 (58%), Gaps = 4/132 (3%)

Query: 20  EEIEPE-RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLP 78
           EE++ E R  W  +  +            NVWRFPYLC  NGGGA+L+P+ V+L+I GLP
Sbjct: 1   EELDAENRPAWNSKLQYILAQIGYSVGLGNVWRFPYLCQKNGGGAYLVPYLVLLIIIGLP 60

Query: 79  LMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSF 138
           L F+EL+ GQ    G + V+N  CP   G+GY   +V   V LYYN+II W+IFY    F
Sbjct: 61  LFFLELAVGQRIRRGSIGVWNYICPRLGGIGYASCLVCFFVGLYYNVIIGWSIFYF---F 117

Query: 139 SSIFYQLPWQNC 150
            S  Y LPW  C
Sbjct: 118 KSFQYPLPWSEC 129


>UniRef50_A3QK28 Cluster: Novel protein similar to vertebrate solute
           carrier family 6 (Neurotransmitter transporter), member
           15; n=9; Danio rerio|Rep: Novel protein similar to
           vertebrate solute carrier family 6 (Neurotransmitter
           transporter), member 15 - Danio rerio (Zebrafish)
           (Brachydanio rerio)
          Length = 304

 Score =  216 bits (527), Expect = 2e-54
 Identities = 125/341 (36%), Positives = 180/341 (52%), Gaps = 40/341 (11%)

Query: 29  WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQ 88
           W  +  +            NVWRFPYLC+ NGGGAF++ + ++L+I G+PL FMEL+ GQ
Sbjct: 3   WDSKLQYVLAQVGFSVGLGNVWRFPYLCHQNGGGAFMLLYVMLLLIIGVPLFFMELAAGQ 62

Query: 89  YAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQ 148
               G + V+    P   G+GY   +V   V LYYN+IIAW++FYM  SF    Y LPW+
Sbjct: 63  SIRQGSIGVWKHISPRLAGIGYSSCMVCFFVALYYNVIIAWSLFYMGNSFQ---YPLPWE 119

Query: 149 NCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAEEYF 208
            C  +       S +   EC A + T Y    F ++  +S +I            + E+ 
Sbjct: 120 QCPVD-----MISNQTVKECAASSPTSYF--WFRKALDISDSI----------DQSGEF- 161

Query: 209 TNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVI 268
            N ++        TG +    A+  LA        + KG++SS KV+YF+++FPY VL+ 
Sbjct: 162 -NPIM--------TGCLLAAWAIVCLA--------MIKGIKSSAKVMYFSSVFPYAVLIC 204

Query: 269 LFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFS 328
              RG+ L GAI GI +   P        QVW  AA Q+FFAL   +G +I  SSYN   
Sbjct: 205 FLIRGLMLDGAIDGIKYMFYPKVEIWGEVQVWRQAATQVFFALGLGYGSVIAYSSYNPIH 264

Query: 329 NNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVD 369
           NNC+ D+++V+  N  TS  A LV+F V+GF A   N+++D
Sbjct: 265 NNCHRDAIMVSGINFMTSVLASLVVFVVLGFRAK--NIALD 303


>UniRef50_Q13032 Cluster: GABA/noradrenaline transporter; n=2; Homo
           sapiens|Rep: GABA/noradrenaline transporter - Homo
           sapiens (Human)
          Length = 732

 Score =  213 bits (519), Expect = 2e-53
 Identities = 100/188 (53%), Positives = 129/188 (68%)

Query: 249 QSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIF 308
           Q   ++VYFTA FPYVVLV+L  RGV LPGA+ GI++YL PD+S+L + QVW DA  QIF
Sbjct: 261 QPGPQIVYFTATFPYVVLVVLLVRGVLLPGALDGIIYYLKPDWSKLGSPQVWIDAGTQIF 320

Query: 309 FALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSV 368
           F+ +   G L  L SYN+F+NNCY D++I+A+ N  TSFFAG V+FS++GF+A E  V +
Sbjct: 321 FSYAIGLGALTALGSYNRFNNNCYKDAIILALINSGTSFFAGFVVFSILGFMAAEQGVHI 380

Query: 369 DRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFP 428
            +V + G GLAFI YP  VT +P++PLW+ LFF MLL LGLDSQ  +          R  
Sbjct: 381 SKVAESGPGLAFIAYPRAVTLMPVAPLWAALFFFMLLLLGLDSQVCMGLWDREPGGGRRE 440

Query: 429 NFRQKKGW 436
             RQ KGW
Sbjct: 441 GCRQGKGW 448



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 27/67 (40%), Positives = 38/67 (56%), Gaps = 4/67 (5%)

Query: 489 GAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGH-YVYPM 547
           GA++F  DI  MIG +   W+  W   W   TP   + I +FN + Y+P  Y + YVYP 
Sbjct: 596 GADRFMDDIACMIGYRPCPWMK-WC--WSFFTPLVCMGIFIFNVVYYEPLVYNNTYVYPW 652

Query: 548 WADAVGW 554
           W +A+GW
Sbjct: 653 WGEAMGW 659



 Score = 38.7 bits (86), Expect = 0.47
 Identities = 16/34 (47%), Positives = 24/34 (70%), Gaps = 1/34 (2%)

Query: 457 GMYWLQLMDKYAANWSVLII-AIGECILIAWIYG 489
           GMY  QL D Y+A+ + L+  A  EC+++AW+YG
Sbjct: 534 GMYVFQLFDYYSASGTTLLWQAFWECVVVAWVYG 567


>UniRef50_Q58715 Cluster: Uncharacterized sodium-dependent
           transporter MJ1319; n=6; Euryarchaeota|Rep:
           Uncharacterized sodium-dependent transporter MJ1319 -
           Methanococcus jannaschii
          Length = 492

 Score =  210 bits (514), Expect = 6e-53
 Identities = 113/339 (33%), Positives = 200/339 (58%), Gaps = 8/339 (2%)

Query: 207 YFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSS-GKVVYFTALFPYVV 265
           YF + +L +SSG+E+ G +  G+ +  LA W IV L L  G+++   K       F   +
Sbjct: 129 YFFHNILQISSGVEDIGGVSYGILVSTLAVWGIVALILSAGIKNGLEKANKIMIPFLLFL 188

Query: 266 LVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYN 325
           +++L    +TLPGA+TGI +YLTPDFS L N  VW  A  QIFF+LS  +G LI  +SY 
Sbjct: 189 IILLVLNALTLPGALTGIEWYLTPDFSALFNYNVWLSAFSQIFFSLSLGFGILIAYASYL 248

Query: 326 KFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPE 385
              ++  I+++ V++ N   SF AG  +F  +G++++   + +D+ V +G GLAF+ +P+
Sbjct: 249 PKKSDLTINAVTVSLLNCGFSFLAGFAVFGTLGYMSYTSGIPLDKAVSEGIGLAFVTFPK 308

Query: 386 VVTRLPI-SPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVF 444
            ++ LP  S L+ I+FF+ L+  G+ S  +++E   +AI+D+F   R+K   ++ ++A+F
Sbjct: 309 ALSLLPFASRLFGIVFFLALVFAGISSAVSIVEASVSAIIDKFSLSRKKA--LLAVLALF 366

Query: 445 GYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQ 504
             +   IFTT +G+Y+L ++D +A+ + + I AI E I+  W++G +K    + ++   +
Sbjct: 367 IIISP-IFTTGAGLYYLDIIDHFASGYLLPIAAILEIIIAIWLFGGDKLREHVNKL--SE 423

Query: 505 SKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHY 543
            KL V+ W  +  +++P  L  ++  +      + YG Y
Sbjct: 424 IKLGVW-WKYLAGVVSPIILTAVVFLDASNVLTSGYGGY 461



 Score = 89.0 bits (211), Expect = 3e-16
 Identities = 40/112 (35%), Positives = 56/112 (50%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           ER +W+    F            N+WRF Y+ Y NGGGAFLIP+ V L+  G+PLM +E 
Sbjct: 5   ERESWSSNLGFILASVGSAIGLGNIWRFGYMVYTNGGGAFLIPYIVALLCVGIPLMILEF 64

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTV 136
           + G Y          K        G+  VI   I+  YY +IIAW ++Y+ +
Sbjct: 65  AIGHYTKKSAPLALEKLHKGSEWTGWFAVISGFIITSYYVVIIAWCLYYLII 116


>UniRef50_UPI0000E460AF Cluster: PREDICTED: similar to inebriated
           protein, partial; n=3; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to inebriated
           protein, partial - Strongylocentrotus purpuratus
          Length = 271

 Score =  209 bits (511), Expect = 1e-52
 Identities = 106/272 (38%), Positives = 153/272 (56%), Gaps = 25/272 (9%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           R  W+ +  F            NVWRFPYLCY +GGGAFLIP+ + L + GLPL+ +E  
Sbjct: 24  REKWSNKAQFILACVGYAVGLGNVWRFPYLCYKSGGGAFLIPYFLTLFLTGLPLLLLEFG 83

Query: 86  FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQL 145
            GQY   GPV  + K  P+F+G G   V+++ ++  YYN+I+ W +FY+  SF S+   L
Sbjct: 84  LGQYIRYGPVEAFKKITPIFKGTGVATVMITFLLTTYYNVIMTWALFYLFASFQSV---L 140

Query: 146 PWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAE 205
           PW  C   W+++ C+S ++           YL    N++   + +I++           +
Sbjct: 141 PWSQCNMTWNSEDCWSQDD-----------YLNLGPNET-QPNGSISS----------TQ 178

Query: 206 EYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVV 265
           EYF ++VL +S GI+E   +R  +   LL AWV+V+ CL KGV +SGKVVYFTA FPY+V
Sbjct: 179 EYFDHRVLQISGGIDEPNGMRWELFGLLLLAWVLVYFCLFKGVATSGKVVYFTATFPYLV 238

Query: 266 LVILFFRGVTLPGAITGILFYLTPDFSQLANA 297
           L++L   G  L GA  GI F   P +  L  A
Sbjct: 239 LIVLLINGALLDGAGDGISFLFKPRWELLKKA 270


>UniRef50_Q9NP91 Cluster: Sodium- and chloride-dependent transporter
           XTRP3; n=19; Theria|Rep: Sodium- and chloride-dependent
           transporter XTRP3 - Homo sapiens (Human)
          Length = 592

 Score =  206 bits (502), Expect = 2e-51
 Identities = 153/544 (28%), Positives = 247/544 (45%), Gaps = 46/544 (8%)

Query: 22  IEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMF 81
           +E  R  W     F            NVWRFPYLC   GGG+FL+P+ +ML++ G+PL++
Sbjct: 1   MEKARPLWANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLY 60

Query: 82  MELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSI 141
           +EL+ GQ    G +  +    P   G+G   V+VS  + +YYN+I AW  +Y+  SF   
Sbjct: 61  LELAVGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQD- 119

Query: 142 FYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYL--RQCFNQSYSVSHNITALAKTAL 199
              LPW  C    +  H   Y+E  ECE  + T Y   R+  N S S+  N     + AL
Sbjct: 120 --PLPWSVCPL--NGNHT-GYDE--ECEKASSTQYFWYRKTLNISPSLQENGGVQWEPAL 172

Query: 200 RRPPAEEYFTNQVLGLSSGIEETGEI---RLGMAMCLLAAWVIVFLCLCKGVQSSGKVVY 256
               A   +    L +  G E TG++      +  C+L  ++I  L L  G  ++G +  
Sbjct: 173 CLLLA---WLVVYLCILRGTESTGKVVYFTASLPYCVLIIYLIRGLTL-HGA-TNGLMYM 227

Query: 257 FTALFPYVVLVILFFRGVTLPGAITGILF---YLTPDFSQLANAQVWGDAAVQIFFALSP 313
           FT     +     +    T      G+ F        +++ +N        V +  + + 
Sbjct: 228 FTPKIEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSLINSFTS 287

Query: 314 AWGGLITLSSYN---KFS-NNCY--IDSLIVAVSNIATSFFAGLVIFSVIGFLAHEL--- 364
            +  ++T S Y     F+  NC   +  L+    ++   F     +  V G+LA      
Sbjct: 288 IFASIVTFSIYGFKATFNYENCLKKVSLLLTNTFDLEDGFLTASNLEQVKGYLASAYPSK 347

Query: 365 ---------NVSVDRVVD---QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQ 412
                    N S++  +D   QG GLAFIVY E +  + +S LWS+L+F MLL LG+ S 
Sbjct: 348 YSEMFPQIKNCSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGIGSM 407

Query: 413 FALMETVTTAILD-RFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANW 471
                 + T + D +  +    K  +  +V +     G++FT  +G YW  + + YAA  
Sbjct: 408 LGNTAAILTPLTDSKIISSHLPKEAISGLVCLVNCAIGMVFTMEAGNYWFDIFNDYAATL 467

Query: 472 SVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFN 531
           S+L+I + E I + ++YG  +F  D++ M GR      + W  MW  ++P  +V + VF 
Sbjct: 468 SLLLIVLVETIAVCYVYGLRRFESDLKAMTGRAVS---WYWKVMWAGVSPLLIVSLFVFY 524

Query: 532 WIEY 535
             +Y
Sbjct: 525 LSDY 528


>UniRef50_Q4SBR6 Cluster: Transporter; n=1; Tetraodon
           nigroviridis|Rep: Transporter - Tetraodon nigroviridis
           (Green puffer)
          Length = 361

 Score =  203 bits (496), Expect = 1e-50
 Identities = 107/273 (39%), Positives = 158/273 (57%), Gaps = 7/273 (2%)

Query: 285 FYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIA 344
           F   P+       +VW DA  Q+FF+ +   G L +L SYNK++NNCY D L +   N  
Sbjct: 18  FQPEPEKEPGCGPEVWADAGTQVFFSYAVCQGVLTSLGSYNKYNNNCYRDCLALCFLNSF 77

Query: 345 TSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVML 404
           TS FAG  +FSV+GF+AH L++S+  V   G GLAFI YP+ ++ LP S  W++LFF+M+
Sbjct: 78  TSIFAGFAVFSVLGFMAHGLDLSLPDVAVSGPGLAFIAYPKALSMLPGSSFWAVLFFLMI 137

Query: 405 LTLGLDSQFALMETVTTAILDRFPNFRQKKG---WVVFIVAVFGYLGGLIFTTNSGMYWL 461
           L LGLD+QF  +E++ T+I D FP   +K G    +V  + +  +L GL   T  G+   
Sbjct: 138 LFLGLDTQFVCVESLATSITDLFPRQLRKPGARELLVLAITIVCFLLGLPLVTQGGIVLF 197

Query: 462 QLMDKYAANW-SVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIIT 520
           QLMD + A+  ++L IA  E I +AW+YGA++F  +I+ MIG Q   ++      W  IT
Sbjct: 198 QLMDTFGASGITLLFIACCETIAVAWVYGADRFYDNIEDMIGYQPLPFL---KYCWLFIT 254

Query: 521 PAALVFILVFNWIEYKPASYGHYVYPMWADAVG 553
           P    F +++N  + +      Y+   WA  VG
Sbjct: 255 PLICGFTMLYNLAQAQSIKVYGYLPGPWASVVG 287


>UniRef50_Q4AKJ6 Cluster: Transporter; n=4; Bacteria|Rep:
           Transporter - Chlorobium phaeobacteroides BS1
          Length = 510

 Score =  200 bits (487), Expect = 1e-49
 Identities = 114/352 (32%), Positives = 190/352 (53%), Gaps = 13/352 (3%)

Query: 205 EEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264
           E +F    L LSS   E G I+  +   LLA W+I +    +GV S G  +      P +
Sbjct: 130 EAFFFQSFLNLSSSPAEIGSIQTPILAGLLAVWLITWGISVRGV-SRGVELANRIFMPLL 188

Query: 265 VLV--ILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322
           +++  IL F  VTL GA+ GI  YL PDF++LA+  VW  A  QIFF LS  +G +I  +
Sbjct: 189 LILTLILVFWSVTLEGAMVGIAAYLQPDFTKLADPMVWISAYGQIFFTLSLGFGIMIAYA 248

Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIV 382
           SY   ++N    +LI A++N   S  +G  +F+V+GF++   N  +D VV +  GLAF+ 
Sbjct: 249 SYMPQNSNMTGSALITALANSGFSLLSGFGVFAVLGFMSVSRNQPLDEVVRESIGLAFVA 308

Query: 383 YPEVVTRL-PISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIV 441
           YP+ ++ +    PL+ +LFF+ L   G+ S  +++E   +   D+F   R+K   +  ++
Sbjct: 309 YPKAISLIGDAGPLFGMLFFLSLTVAGISSSISIVEAFVSGAEDKFGINRKK---LSTVL 365

Query: 442 AVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMI 501
              G++GG+IFTTN G++WL ++D +  N+ +++  + ECI++ W +  +     + ++ 
Sbjct: 366 CFLGFVGGIIFTTNGGLFWLDIVDHFINNYGLVVAGLLECIVVGWFFNLDIIRKHLNKVS 425

Query: 502 GRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVG 553
             Q   W   W+ + ++  P  L  IL+   I     +YG Y    WA  +G
Sbjct: 426 NMQLGTW---WNWIIKLCLPLFLSVILLNQLIRELFTAYGDY---SWASLIG 471



 Score = 81.0 bits (191), Expect = 9e-14
 Identities = 39/115 (33%), Positives = 57/115 (49%), Gaps = 1/115 (0%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           R  W  R  F            N+WRF YL Y NGGGAFLIP+ V L  AG+PL+ +E  
Sbjct: 8   RSTWKSRSGFILAAIGSAVGLGNIWRFSYLTYENGGGAFLIPYLVALFTAGIPLLILEFG 67

Query: 86  FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSI-VMLYYNLIIAWTIFYMTVSFS 139
            G          + K    +  LG+  ++ +   ++LYY ++IAW I ++  S +
Sbjct: 68  IGHERIGSAPLAFRKIGRRWEWLGWWPLMFTMFGIVLYYAVVIAWCIDFIFYSIN 122


>UniRef50_UPI00015A63D4 Cluster: Sodium-dependent dopamine
           transporter (DA transporter) (DAT).; n=1; Danio
           rerio|Rep: Sodium-dependent dopamine transporter (DA
           transporter) (DAT). - Danio rerio
          Length = 589

 Score =  199 bits (485), Expect = 2e-49
 Identities = 117/336 (34%), Positives = 171/336 (50%), Gaps = 15/336 (4%)

Query: 242 LCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWG 301
           LC    +     VV+ TA  PYVVL +L  RGVTLPGAI GI  YL+ DF +L +     
Sbjct: 232 LCKYDALMLYSDVVWITATMPYVVLTVLLLRGVTLPGAIDGIKAYLSVDFLRLYDVSGGV 291

Query: 302 DAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLA 361
            AA     AL       + +         C+ D++I +  N  TSFF+G VIFS +G+++
Sbjct: 292 SAAALCCVALCVCVCVCVCV---------CFRDAIITSSINSLTSFFSGFVIFSFLGYMS 342

Query: 362 HELNVSVDRVVDQGA-GLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVT 420
            + NV++D+V   G  GL FI+YPE +  LP S +W+++FF+MLLTLG+DS    ME+V 
Sbjct: 343 QKHNVALDKVATDGRPGLVFIIYPEAIATLPGSSVWAVIFFIMLLTLGIDSAMGGMESVI 402

Query: 421 TAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGE 480
           T ++D F    + +      + V  +L  LI  TN G+Y   L+D +AA  S+L   + E
Sbjct: 403 TGLIDEFKFLHKHRELFTLFIVVSTFLISLICVTNGGIYVFTLLDHFAAGTSILFGVLIE 462

Query: 481 CILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASY 540
            I IAW Y  + F   +       S   +    ++    TP +  F++V ++  + P  Y
Sbjct: 463 AIGIAWFYETDVFSDSVT----NHSSPSLQCSLSVQHHNTPQS-QFMVVISFATFNPPKY 517

Query: 541 GHYVYPMWADAVGWTXXXXXXXXXXXXXXDQICSGP 576
           G Y +P WA  VGW                + CS P
Sbjct: 518 GSYYFPTWATMVGWCLSISSMIMVPLYAIYKFCSLP 553



 Score =  143 bits (346), Expect = 1e-32
 Identities = 61/135 (45%), Positives = 85/135 (62%), Gaps = 5/135 (3%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           +R  W  + DF            NVWRFPYLCY NGGGAFL+P+   +VIAG+PL +MEL
Sbjct: 75  QRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLFFMVIAGMPLFYMEL 134

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
           + GQY   G   V+ K CP+F+G+G+ ++++S  V  YYN+IIAW +FY+  SFS     
Sbjct: 135 ALGQYNREGAAGVW-KICPIFKGVGFTVILISLYVGFYYNVIIAWALFYLFSSFSG---- 189

Query: 145 LPWQNCKAEWSTKHC 159
            PW +C   W++ +C
Sbjct: 190 EPWIHCNNTWNSPNC 204


>UniRef50_Q8TQM2 Cluster: Sodium/chloride-dependent noradrenaline
           transporter; n=1; Methanosarcina acetivorans|Rep:
           Sodium/chloride-dependent noradrenaline transporter -
           Methanosarcina acetivorans
          Length = 489

 Score =  196 bits (478), Expect = 1e-48
 Identities = 112/342 (32%), Positives = 188/342 (54%), Gaps = 14/342 (4%)

Query: 207 YFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQS----SGKVVYFTALFP 262
           +F N++L +S      G     + + LLA W+I+++   +GVQ+    S K+  F  L  
Sbjct: 127 FFNNELLHVSDSPWNLGSFSYPVLIGLLATWLIIWVVEKRGVQAGIERSSKI--FIPLL- 183

Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322
           +V+L++L FR +TL G+I GI +YL PDFS+L + +VW  A  Q F++LS     +IT S
Sbjct: 184 WVLLIVLVFRAITLEGSINGIEWYLKPDFSKLTDIKVWQAAYGQAFYSLSLGMAIMITYS 243

Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIV 382
           SY    ++   ++ IV++++ A SF  G  IF  +G++A+   + ++ VV Q  GLAF+V
Sbjct: 244 SYLSKKSDIVNNAFIVSLADGAFSFTMGFAIFGTLGYMAYAKGLGIEEVVAQSIGLAFVV 303

Query: 383 YPEVVTRLP-ISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIV 441
            PE +  LP +  L ++ FF+ +    L S  +L+E   ++I+D+   F  K+G  V + 
Sbjct: 304 LPEALNMLPGLKALTAVAFFLCIAIAALSSLISLVEAFASSIMDK---FEVKRGKAVDLT 360

Query: 442 AVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMI 501
             FG L  LI+ T  G+YWL ++D +   + ++I+ I E + I WIYGA+K         
Sbjct: 361 IGFGLLFSLIYATRGGIYWLDIIDHFINTYGLIIVGILETVAIGWIYGADKIREWANNYS 420

Query: 502 GRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHY 543
              + +W   W A  +++ P  L++I+  +      A Y  Y
Sbjct: 421 DIMAGIW---WDACIKLVIPVVLLYIVFVDTRSNLAAPYEGY 459



 Score = 89.4 bits (212), Expect = 3e-16
 Identities = 39/112 (34%), Positives = 63/112 (56%), Gaps = 2/112 (1%)

Query: 29  WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFG- 87
           W  R  F            N+WRF Y+ Y NGGGAFLIP+ + L+ AG+PLM +E   G 
Sbjct: 7   WNTRVGFILAAIGSAVGLGNIWRFSYMAYENGGGAFLIPYFIALLTAGIPLMILEFGLGS 66

Query: 88  QYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFS 139
           ++    P++ + +    F  +G+  VI S I+  YY++I+ W++ Y+  +F+
Sbjct: 67  KFLGSAPLS-FKRAKKSFEWIGWWGVIASFIITTYYSVIVGWSLVYLLKAFT 117


>UniRef50_UPI00006CA50D Cluster: Sodium:neurotransmitter symporter
           family protein; n=3; Tetrahymena thermophila SB210|Rep:
           Sodium:neurotransmitter symporter family protein -
           Tetrahymena thermophila SB210
          Length = 588

 Score =  194 bits (474), Expect = 5e-48
 Identities = 104/295 (35%), Positives = 161/295 (54%), Gaps = 7/295 (2%)

Query: 200 RRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTA 259
           ++P  ++YF    L  SSG++E G I   +  C L + VIV+ C+ KGV  SGK+  FTA
Sbjct: 187 QKPWNKDYFYKNFLNSSSGLDELGGIVWPIFFCYLLSQVIVYFCIQKGVSVSGKIALFTA 246

Query: 260 LFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLI 319
             PY++L IL  RG+ L GA TGI +  +PD+S+L++ QVW DAA QI F +S   G LI
Sbjct: 247 TSPYILLFILMLRGLFLEGAFTGISYLFSPDWSKLSDLQVWVDAANQIIFQVSTGCGVLI 306

Query: 320 TLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLA 379
              SY   S      S +V +  +   F A  VIFS +G+++H    S+  +   G  LA
Sbjct: 307 IFGSYRPVSQEIKQTSYMVPMLTVLCGFLASFVIFSFMGYMSHLTGQSIQDIPLSGPDLA 366

Query: 380 FIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFP-------NFRQ 432
           F+V+P V+T +P S L SI+FF+ ++ LG+D+QFA M+ +  +I D F        N   
Sbjct: 367 FVVFPAVLTLMPFSNLLSIIFFLTMVFLGIDTQFAFMDGLAGSIEDEFHGTDAKIFNITI 426

Query: 433 KKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWI 487
            +  +   +     L   +++T +G Y+L+ +D Y    +++     E     W+
Sbjct: 427 TQKHIRMGICSIVSLSAFLYSTQAGFYYLEFIDSYGVGINLITAVFMEVYFFNWM 481



 Score = 98.3 bits (234), Expect = 5e-19
 Identities = 45/129 (34%), Positives = 71/129 (55%), Gaps = 3/129 (2%)

Query: 20  EEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPL 79
           +E   ER  +   +++            +VWRFPYL + NGGG FLIP+ + L + G P 
Sbjct: 54  DENHHERDRFNSYYEYLVSVLGFAAGFGSVWRFPYLIFKNGGGVFLIPYFIFLFLIGFPS 113

Query: 80  MFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFS 139
            + E + GQ    GP  ++ K    ++GLG   V V+  +  YYNLI+A++I+++  SF+
Sbjct: 114 FYFETAIGQIFQRGPPLIFEKIHKKWKGLGIFPVCVNFSMSTYYNLILAYSIYFLWKSFT 173

Query: 140 SIFYQLPWQ 148
              Y LPW+
Sbjct: 174 ---YPLPWK 179


>UniRef50_Q4SNN5 Cluster: Transporter; n=1; Tetraodon
           nigroviridis|Rep: Transporter - Tetraodon nigroviridis
           (Green puffer)
          Length = 486

 Score =  185 bits (450), Expect = 4e-45
 Identities = 86/169 (50%), Positives = 116/169 (68%)

Query: 211 QVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILF 270
           ++L +S GIEE G +   + +CLLA+WV  +  + KGV+S+GKV YFTA FPYV+L+IL 
Sbjct: 149 RMLRMSRGIEEVGSVSWELLLCLLASWVFCYFSIWKGVRSTGKVAYFTATFPYVMLLILL 208

Query: 271 FRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNN 330
            RG+TLPGA  GI FYL P+   L N +VW +A  QI ++ S A G LI L SYNK++NN
Sbjct: 209 IRGLTLPGAFDGIYFYLYPNLEDLTNLEVWIEAGSQICYSYSLAIGNLIVLGSYNKYNNN 268

Query: 331 CYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLA 379
           CY D L + + N  TSF AG V+FSV+GF+A +  V++D V D G  L+
Sbjct: 269 CYKDCLWICLLNSCTSFVAGFVVFSVLGFMAQKQGVTIDVVADSGQELS 317



 Score =  130 bits (314), Expect = 1e-28
 Identities = 55/131 (41%), Positives = 79/131 (60%), Gaps = 4/131 (3%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           RG W  + ++            NVWRFPYLCY  GGGAFLIP+T+++V+ G+PL  +E S
Sbjct: 15  RGQWASKTEYILVVAGNVVGLGNVWRFPYLCYRYGGGAFLIPYTLLVVVFGIPLFLLETS 74

Query: 86  FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQL 145
            GQ+   G +  + K CPL +G+GYG +++  +  L Y +I AW +FY+  SF S   +L
Sbjct: 75  LGQFTQEGFITCWRKICPLAQGVGYGYLVL-KVYELVYIIIQAWALFYLVFSFRS---EL 130

Query: 146 PWQNCKAEWST 156
           PW  C   W+T
Sbjct: 131 PWATCNNSWNT 141



 Score = 35.5 bits (78), Expect = 4.3
 Identities = 19/67 (28%), Positives = 32/67 (47%), Gaps = 4/67 (5%)

Query: 489 GAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGH-YVYPM 547
           GA++    I   IG++  ++  L    W+ +TPA  +   +    +Y+       YVYP 
Sbjct: 369 GADRLLDIIGDSIGQRPSVFFKL---CWKYVTPALSLISYILYLSDYRDLKINDWYVYPN 425

Query: 548 WADAVGW 554
           WA  +GW
Sbjct: 426 WAYVLGW 432


>UniRef50_A0UVQ7 Cluster: Transporter; n=5; Clostridium|Rep:
           Transporter - Clostridium cellulolyticum H10
          Length = 502

 Score =  183 bits (446), Expect = 1e-44
 Identities = 101/329 (30%), Positives = 181/329 (55%), Gaps = 11/329 (3%)

Query: 228 GMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYL 287
           G+ +  L  W + +  +  G++   K++  T +   V ++I+  RGVTLPGA  G+    
Sbjct: 153 GITIIWLLNWFVCYKGVSGGIEKLNKILLPTLV---VAMIIIVIRGVTLPGASLGLNKLF 209

Query: 288 TPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSF 347
           +PD+S++ + +VW  A  Q+FF+LS A G +IT SSY     +    + + A +N    F
Sbjct: 210 SPDWSKVLDPKVWIAAYGQVFFSLSLAMGIMITYSSYLPKKTDINNSAFMTAFANSGFEF 269

Query: 348 FAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRL-PISPLWSILFFVMLLT 406
            + + +F+++G++A    V VD+V  QG GLAFI +P+V T +  I  L+ +LFF+ L+ 
Sbjct: 270 LSAIGVFAILGYMASTQGVGVDKVASQGIGLAFIAFPKVFTVMGGIGKLFGVLFFICLVF 329

Query: 407 LGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDK 466
            G+ S  +L+E  ++A++D+    R+K   VV +V + GY   ++++T +G+Y+L ++D 
Sbjct: 330 AGITSSISLVEASSSALIDKTGAGRKK---VVSLVCLVGYSISIVYSTGAGLYFLDIIDN 386

Query: 467 YAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVF 526
           +  ++ ++ + + E I I W++GA K       +       W   W+ M + ITP  L F
Sbjct: 387 FINSYGIVTVGLLEAITIGWLFGASKIREHTNAISYFSIGKW---WNVMVKFITPLILTF 443

Query: 527 ILVFNWIEYKPASYGHYVYPMWADAVGWT 555
           +++ N +      YG Y       A GW+
Sbjct: 444 MIISNIVNEIIKPYGGYSQKALI-AFGWS 471



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 40/115 (34%), Positives = 60/115 (52%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           +R  W  +  F            N+WR+PY+ Y+NGGGAFLIP+   ++ AG+PLM ME 
Sbjct: 4   KRDQWGSKAGFILAAIGSAVGLGNIWRYPYVLYSNGGGAFLIPYFFAILTAGIPLMIMEY 63

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFS 139
             G      P   + +    +  LG+   I S I++ YY LI++W I Y+  S +
Sbjct: 64  GLGHKFKGSPPLAFARANKRWEWLGWWPSINSFIILTYYTLILSWAINYLYFSIT 118


>UniRef50_Q4RSW5 Cluster: Transporter; n=2; Tetraodontidae|Rep:
           Transporter - Tetraodon nigroviridis (Green puffer)
          Length = 616

 Score =  183 bits (445), Expect = 1e-44
 Identities = 102/268 (38%), Positives = 142/268 (52%), Gaps = 33/268 (12%)

Query: 16  APLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIA 75
           AP+  + +  R  W+ + DF            NVWRFPY+CY NGGGAFLIP+ +M +  
Sbjct: 23  APVITQTD-SRDKWSKKMDFLLSVIGFAVDLGNVWRFPYICYQNGGGAFLIPYVLMAIFG 81

Query: 76  GLPLMFMELSFGQYAALGPVAVYNKFCPLFR-GLGYGMVIVSSIVMLYYNLIIAWTIFYM 134
           G+PL +MEL+ GQ+   G ++++   CP+F+ G+GY + +++  V  YYN IIAW +FY 
Sbjct: 82  GVPLFYMELAMGQFHRTGAISIWKHICPIFKGGIGYAICVIALYVSFYYNTIIAWALFYF 141

Query: 135 TVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITAL 194
             SFSSI   LPW NC   W+T  C +Y   D                       NIT  
Sbjct: 142 YSSFSSI---LPWTNCDNVWNTPDCTNYFGRD-----------------------NIT-- 173

Query: 195 AKTALRRPPAEEYFTNQVLGL--SSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSG 252
             T   R PAEE++T  VL L  SSG++  G +R  + +CL   + IV+  L KGV++SG
Sbjct: 174 -WTNFSRSPAEEFYTRNVLELHKSSGLKNVGGVRWQLMLCLFLIFTIVYFSLWKGVKTSG 232

Query: 253 KVVYFTALFPYVVLVILFFRGVTLPGAI 280
           KV    AL     L+       TLPG +
Sbjct: 233 KVAALEALVFSPALITHQMCTPTLPGGV 260



 Score =  173 bits (422), Expect = 9e-42
 Identities = 82/195 (42%), Positives = 129/195 (66%), Gaps = 4/195 (2%)

Query: 298 QVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVI 357
           QVW DAA QIFF+L P +G L+ LSSYN F+NNCY D+++ ++ N  TSF +G VIF+V+
Sbjct: 325 QVWVDAAAQIFFSLGPGFGVLLALSSYNPFTNNCYRDAIVTSLVNCLTSFVSGFVIFTVL 384

Query: 358 GFLAHELNVSVDRVV-DQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALM 416
           G++A    V V+ V  D+G  L FI YPE +  +  S  ++I+FFVM++ LGLDS F  +
Sbjct: 385 GYMAEMRKVEVEDVARDKGPSLLFITYPEAIANMMGSTFFAIIFFVMMIMLGLDSTFGGL 444

Query: 417 ETVTTAILDRFPN--FRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVL 474
           E + TA+LD +P+  + +++ +V+ +V V  +LG L   TN G Y ++L++++    S++
Sbjct: 445 EAIITAVLDEYPDHLYHRRELFVLCLVVVC-FLGSLSTLTNGGAYVVKLLEEFGVGCSII 503

Query: 475 IIAIGECILIAWIYG 489
            +   E I ++W YG
Sbjct: 504 ALGFLEAIAVSWFYG 518


>UniRef50_A0DZD7 Cluster: Transporter; n=3; Paramecium
           tetraurelia|Rep: Transporter - Paramecium tetraurelia
          Length = 533

 Score =  181 bits (441), Expect = 5e-44
 Identities = 99/305 (32%), Positives = 167/305 (54%), Gaps = 6/305 (1%)

Query: 201 RPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTAL 260
           +P + +YF + ++ +S+ I +   I  G+ +  + + +IV+ C+ +GV++SGK+   TA 
Sbjct: 142 KPFSRDYFYDSIVQISTCITDLNHIIWGLFIAYIVSLIIVYFCIKEGVETSGKIAIVTAT 201

Query: 261 FPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLIT 320
            PY++L+IL  RG+ L G+  GI F   PDF +L N  VW DAA Q+ F +S     L  
Sbjct: 202 SPYILLMILLIRGLMLEGSSEGIYFLFKPDFVKLFNPSVWVDAANQVIFQMSVGQAILCL 261

Query: 321 LSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAF 380
             SY K  +N    S  + +        AGLV+FS IG ++ + NVS+ ++   G  LAF
Sbjct: 262 YGSYRKKDDNLSNFSFAIPLLTALCGMLAGLVVFSYIGHVSFKFNVSISQLPLSGPDLAF 321

Query: 381 IVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFI 440
           ++YP ++ ++P+  LW ILFF++LL LG+D+QF  ++ +   I D +       G+ + +
Sbjct: 322 VLYPAILAQMPMPNLWCILFFLVLLMLGIDTQFGFVDGIAGTIEDIYLGEVIVCGYKLTV 381

Query: 441 ----VAVFGYLG--GLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFC 494
               ++V   LG  GLI+ T+ G Y L  +D +  N S ++  + E          EK  
Sbjct: 382 QQVRLSVCSILGVIGLIYCTDIGFYLLSFVDTFGTNVSFMLGVLFEVFYFGSKERFEKLK 441

Query: 495 GDIQR 499
            D+++
Sbjct: 442 MDLEK 446



 Score = 93.5 bits (222), Expect = 2e-17
 Identities = 40/122 (32%), Positives = 68/122 (55%), Gaps = 3/122 (2%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           R  ++  + F            +VWRFPYL + NGGG FLIP+ +++    +PL F+E+ 
Sbjct: 15  RMKFSSSWTFMLTSLGFAAGFGSVWRFPYLVFKNGGGTFLIPYFILVFTLAIPLFFLEVG 74

Query: 86  FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQL 145
            GQ   +G   + +   P+ +G GY  +++ + +  YYNLI+A+++ Y+  SF    Y +
Sbjct: 75  LGQCKGIGMAHLLDIEKPMLKGFGYVGIVICAYISTYYNLIMAYSLRYLWESFK---YPI 131

Query: 146 PW 147
           PW
Sbjct: 132 PW 133


>UniRef50_Q1NTI5 Cluster: Transporter; n=2; delta proteobacterium
           MLMS-1|Rep: Transporter - delta proteobacterium MLMS-1
          Length = 574

 Score =  180 bits (437), Expect = 1e-43
 Identities = 118/356 (33%), Positives = 185/356 (51%), Gaps = 27/356 (7%)

Query: 205 EEYFTNQVLGLSSGIEETGEIR----LGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTAL 260
           E +F  Q L LS    + G IR       A   LA W I +  +  G++ + K+     L
Sbjct: 183 EGFFFGQFLQLSDSAGQLGGIRWPILAATAFIWLACWAICYRDIRHGIEKAAKLFMPLLL 242

Query: 261 FPYVVLVILFFRGVTLPGAITGILF-YLTPDFSQL-----------ANAQVWGDAAVQIF 308
               +LV+  F   TL GA  GI+  YL+ D+S++           A  QVW  A  QIF
Sbjct: 243 LLTTILVVWVF---TLEGAREGIISNYLSADWSKINFLSGDAASRIAAGQVWVAAFGQIF 299

Query: 309 FALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSV 368
           F LS  +G +I  +SY     N   +++I A +N   S FAGL +F ++GF+AH   V  
Sbjct: 300 FTLSLGFGIMIAYASYLPRQTNLARNAVITAAANCFYSIFAGLAVFGIVGFMAHSQGVGF 359

Query: 369 DRVVDQGAGLAFIVYPEVVTRLP-ISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRF 427
           D  +  G  LAF+VYP+ +  LP  + L+  LFF++L+  GL S  +L+E  T+A+ D++
Sbjct: 360 DDAIQGGPQLAFVVYPQAIYLLPDFNALFGALFFLVLIIAGLTSGVSLIEAFTSALTDKY 419

Query: 428 PNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWI 487
            N+ +KK  VV ++ + G LG  +FT+  G+Y L ++D +  N+ ++   +  C+++ W 
Sbjct: 420 -NWSRKK--VVSVICLLGLLGSTLFTSRGGLYLLDIVDHFVTNYGLVGGGLLLCLVVGWY 476

Query: 488 YGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHY 543
            G EK    I R+  R S  W   W+   RI+TP  L+ +L+        ++YG Y
Sbjct: 477 SGPEKMRRHISRLGSRVSP-W---WNFFIRILTPLVLISLLLIALYGDLTSNYGDY 528



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 41/116 (35%), Positives = 65/116 (56%), Gaps = 3/116 (2%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           ER  W     F            N+WRF Y+ + +GGGAFL+P+ V L++AG+PL+ +E 
Sbjct: 60  ERITWHSNIGFLMAAIGSAIGLGNIWRFSYMAHEHGGGAFLVPYLVALLVAGIPLILLEY 119

Query: 85  SFG-QYAALGPVAVYNKFCPLFRGLGYGMVIVSSI-VMLYYNLIIAWTIFYMTVSF 138
             G +    GP+A+  +    F GLG+ M +V+   +MLYY++++ W + Y   SF
Sbjct: 120 GLGHREKGSGPLAL-ARINRRFEGLGWWMPVVAMFGIMLYYSVVMGWCVNYFFFSF 174


>UniRef50_O50649 Cluster: TnaT protein; n=1; Symbiobacterium
           thermophilum|Rep: TnaT protein - Symbiobacterium
           thermophilum
          Length = 501

 Score =  173 bits (422), Expect = 9e-42
 Identities = 97/344 (28%), Positives = 182/344 (52%), Gaps = 15/344 (4%)

Query: 207 YFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVL 266
           +F++  LG++SG  E G +R G+   +   W   +    +G+ S G       + P++++
Sbjct: 128 FFSSDFLGITSGPLELGGLRWGIFAAVAVVWFANYYISAQGI-SGGIEKACKIMTPFLIV 186

Query: 267 VILFF--RGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSY 324
            +L F  RG+TLPGA  G+ ++L PDFS++ +  VW  A  Q+FF+ + A G +I  +SY
Sbjct: 187 AMLIFVIRGITLPGATYGLNYFLNPDFSKIMDPGVWVAAYSQVFFSTTLAVGVMIAYASY 246

Query: 325 NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYP 384
               ++   ++ I   +N +  F AGL +FS +G+ A    V  + +   G G+AF+ +P
Sbjct: 247 VPEDSDLANNAFITVFANSSFDFMAGLAVFSTLGYAAVTAGVPFEEMAVAGPGVAFVAFP 306

Query: 385 EVVTRLP----ISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK-KGWVVF 439
           + ++ LP    +  L+ ILFF  LL  G+ S  + ME+  +A++DRF   R+K  GW   
Sbjct: 307 KAISMLPGPTWLQSLFGILFFSALLLAGISSSISQMESFASAVIDRFGVDRKKLLGW--- 363

Query: 440 IVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQR 499
             ++ G+    +F T +G++ L ++D +  ++++ I+ + E I++ +I G  +    +  
Sbjct: 364 -FSLIGFAFSALFATGAGVHILDIVDHFVGSYAIAILGLVEAIVLGYIMGTARIREHVNL 422

Query: 500 MIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHY 543
               +  +W   W  + + +TP  L + ++ N+I      Y  Y
Sbjct: 423 TSDIRVGMW---WDVLVKYVTPVLLGYNILSNFISEFREPYAGY 463



 Score =   99 bits (238), Expect = 2e-19
 Identities = 41/118 (34%), Positives = 65/118 (55%)

Query: 22  IEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMF 81
           +E +R  W  R  F            N WRFP++ Y NGGGAFL+P+ V L+ AG+PLM 
Sbjct: 1   MEAQRDQWKSRSGFIFATIGAAVGLGNFWRFPFMAYQNGGGAFLLPYFVALLTAGVPLMI 60

Query: 82  MELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFS 139
           +E  FG       +  + K    F  +G+  + V  +V+ +Y++II+W++ Y+  SF+
Sbjct: 61  LEFGFGHKMRTATITAFKKLNRRFEWIGWWQITVPVVVVTFYSVIISWSLRYLIFSFT 118


>UniRef50_Q9KQI6 Cluster: Sodium-dependent transporter; n=34;
           Proteobacteria|Rep: Sodium-dependent transporter -
           Vibrio cholerae
          Length = 527

 Score =  171 bits (415), Expect = 6e-41
 Identities = 107/350 (30%), Positives = 178/350 (50%), Gaps = 17/350 (4%)

Query: 207 YFTNQVLGLSSGIEET-GEIRLGMAMCLLAAWVIVFLCLC----KGVQSSGKVVYFTALF 261
           YF ++ L L        G I+  +A  +L AWVI +  +     KG++ + K++    LF
Sbjct: 167 YFFSEYLKLGDNSPTNLGSIQWHIAFAMLIAWVITYAAIVGGVKKGIERASKIM-MPILF 225

Query: 262 PYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITL 321
             ++++IL  R + LPGA+ G+ +   PDFS++ + +VW  A  QIFF LS  +  ++  
Sbjct: 226 --IMVLILIARMIFLPGALDGVNYMFQPDFSKIWDVKVWAAAYGQIFFTLSIGFAIMLAY 283

Query: 322 SSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFI 381
           SSY    ++   ++ +  + N   S  AG++IFSV+G++A E    +  VV  G GLAF+
Sbjct: 284 SSYLPEKSDITNNAFMTVLINCGFSVLAGIMIFSVLGYMAQEQGKPLTEVVSAGVGLAFV 343

Query: 382 VYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIV 441
             P  +  LPI  +   LFF+ L+  GL S  ++ME VT+A++D+    R+K      IV
Sbjct: 344 TLPAAINLLPIPYILGPLFFLALVVAGLSSHISIMEAVTSALIDKLGWSRKK---AANIV 400

Query: 442 AVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMI 501
              G+L  + F TN G+  L L+D +A N  ++   + E +L+ W+        D+++ +
Sbjct: 401 IGIGFLVSMAFATNGGLLLLDLVDHFANNVGIMASCLVELVLMTWLLK----ISDVRKYV 456

Query: 502 GRQSKLWVYLW-SAMWRIITPAALVFILVFNWIEYKPASYGHYVYPM-WA 549
              S   V +W     R ++P  L  I+           YG Y   + WA
Sbjct: 457 NSISDFSVGVWFDICLRFVSPVILAIIVATKLQALFTEGYGGYDLTLGWA 506



 Score = 94.3 bits (224), Expect = 9e-18
 Identities = 44/130 (33%), Positives = 64/130 (49%)

Query: 10  DEEKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFT 69
           DE+       +E+  +R  W  R  F            N+WRFPY+ Y NGGGAF IP+ 
Sbjct: 28  DEKLHTLGYYKELFMKREQWGSRVGFVLAAVGSAIGLGNIWRFPYMAYENGGGAFFIPYL 87

Query: 70  VMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAW 129
             +V AG+P M +E S GQ           K    F  LG+  V +++++ +YY  +I W
Sbjct: 88  FAMVTAGIPFMILEFSMGQKHRGSAPTTLAKIHSKFEWLGWFQVGIAAVIAVYYVAVIGW 147

Query: 130 TIFYMTVSFS 139
            I Y  +SF+
Sbjct: 148 AISYFGMSFT 157


>UniRef50_A7RZ73 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 537

 Score =  170 bits (414), Expect = 8e-41
 Identities = 83/230 (36%), Positives = 128/230 (55%), Gaps = 19/230 (8%)

Query: 24  PERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFME 83
           P R +W  + DF            N WRFPYLCY +GG +FL P+ +ML + G+P+ FME
Sbjct: 2   PRRESWNSKLDFFLATLGYIVGFGNFWRFPYLCYRSGGASFLFPYFLMLFVIGIPMFFME 61

Query: 84  LSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFY 143
           LS GQ+   G V+V+   CPL  GLGYG +++  +  +YY +I+AW +FY+  SF S   
Sbjct: 62  LSVGQWYEAGMVSVWKAVCPLASGLGYGTLLMQLLSNIYYIVILAWVLFYLFDSFRS--- 118

Query: 144 QLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPP 203
            +PW++C   W+T  C +   A +    +        F    + S   T+         P
Sbjct: 119 HVPWESCGNWWNTPFCRTQRTASQTVNCSA-------FALPVNCSQTFTS---------P 162

Query: 204 AEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGK 253
           +EEY+TN+VL ++  +E+ GEIR  +   L+ +WV+V+ C+ K V+ +GK
Sbjct: 163 SEEYWTNRVLQITDSLEDMGEIRWELVGTLILSWVLVYFCIFKSVRLTGK 212



 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 55/144 (38%), Positives = 78/144 (54%), Gaps = 4/144 (2%)

Query: 412 QFALMETVTTAILDRFPNFRQKKGWVVFI-VAVFGYLGGLIFTTNSGMYWLQLMDKYAAN 470
           QF  +E + T I+D +P   + K W+V + + V   L GL   T  GMY   L D  AA 
Sbjct: 360 QFGAIEALATGIIDEYPAKLRAKKWLVLLGLCVALGLLGLSCITQGGMYVFNLFDYQAAG 419

Query: 471 WSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVF 530
            S+L + + E + IAWIYG ++F  DI+ M G++  +WV L     + ITPA    I++ 
Sbjct: 420 LSLLFMVLLENVYIAWIYGMDRFSNDIEVMTGQKPYIWVTL---CLKYITPACSSAIILA 476

Query: 531 NWIEYKPASYGHYVYPMWADAVGW 554
           N I +    Y    YP WA+AVGW
Sbjct: 477 NMINWTGIKYDGRPYPGWAEAVGW 500


>UniRef50_UPI0000661366 Cluster: Sodium- and chloride-dependent
           glycine transporter 2 (GlyT2) (GlyT-2) (Solute carrier
           family 6 member 5).; n=2; Takifugu rubripes|Rep: Sodium-
           and chloride-dependent glycine transporter 2 (GlyT2)
           (GlyT-2) (Solute carrier family 6 member 5). - Takifugu
           rubripes
          Length = 268

 Score =  170 bits (413), Expect = 1e-40
 Identities = 78/110 (70%), Positives = 92/110 (83%)

Query: 253 KVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALS 312
           +VVYFTA FPYVVL+IL  RGVTLPGA  GIL+++TP + +L +A+VW DAA QIFF+LS
Sbjct: 159 QVVYFTATFPYVVLIILLIRGVTLPGAFDGILYFITPKWEKLNDAKVWKDAATQIFFSLS 218

Query: 313 PAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAH 362
            AWGGLITLSSYNKF NNCY D++IV  +N ATS FAG VIFSVIGF+AH
Sbjct: 219 AAWGGLITLSSYNKFHNNCYRDTVIVTCTNSATSIFAGFVIFSVIGFMAH 268



 Score =  149 bits (361), Expect = 2e-34
 Identities = 62/134 (46%), Positives = 90/134 (67%), Gaps = 4/134 (2%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           RGNW+ + DF            NVWRFPYL + NGGGAFLIP+  ML IAG+P+  +E+S
Sbjct: 6   RGNWSNKMDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLTMLGIAGIPIFLLEVS 65

Query: 86  FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQL 145
            GQ+A+ GPV+V+ K  P  +G G  M+I+S ++ +YYN+I+ WT++Y+   F+S+   L
Sbjct: 66  LGQFASQGPVSVW-KCIPALQGCGIAMLIISVLIAIYYNIIMCWTLYYL---FASLKGSL 121

Query: 146 PWQNCKAEWSTKHC 159
           PW NC+ +W+T  C
Sbjct: 122 PWANCRNDWNTVEC 135


>UniRef50_Q6PBA3 Cluster: Solute carrier family 6 (Neurotransmitter
           transporter), member 19; n=2; Danio rerio|Rep: Solute
           carrier family 6 (Neurotransmitter transporter), member
           19 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 651

 Score =  168 bits (409), Expect = 3e-40
 Identities = 72/177 (40%), Positives = 116/177 (65%)

Query: 187 VSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCK 246
           ++ N T       +  P + ++  + L  S+ I++TG +++ M +CL++AW ++++C  +
Sbjct: 156 INENRTGPIPECGKSSPVDYFWYRETLNTSAAIDDTGGLQVWMVLCLISAWAVLYVCCIR 215

Query: 247 GVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQ 306
           G++++GK VY T+  PY+VL I   RG+TL G++ GI F  TPD ++LAN   W DA  Q
Sbjct: 216 GIETTGKAVYVTSTLPYLVLTIFLIRGLTLKGSVDGIKFLFTPDINELANPSTWLDAGAQ 275

Query: 307 IFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHE 363
           +F++ S A+GGLI+ SSYN   NNC  D++I++V N  TS +A  VI+S+IGF A E
Sbjct: 276 VFYSFSLAFGGLISFSSYNSVHNNCEQDAVIISVINAFTSIYAATVIYSIIGFRATE 332



 Score =  127 bits (307), Expect = 8e-28
 Identities = 71/180 (39%), Positives = 103/180 (57%), Gaps = 7/180 (3%)

Query: 353 IFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQ 412
           I S +     +LN  +   V+ G GLAFIV+ E +T++P+SPLWS+LFF+ML  LGL S 
Sbjct: 375 IISSLSLKTCDLNNFLSEGVE-GTGLAFIVFTEAITKMPLSPLWSVLFFIMLFCLGLSSM 433

Query: 413 FALMETVTTAILDR--FPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAAN 470
           F  +E V   + D   FP    K+  +  +  +   L GLIF   SG YWL L D +A +
Sbjct: 434 FGNIEGVLVPLQDLGVFPKSWPKE-IISGVTCLVCCLVGLIFVQGSGNYWLALFDSFAGS 492

Query: 471 WSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVF 530
             +LIIA  E I + ++YG ++F  D+  MIG +  ++   W A WR I+P  ++ I VF
Sbjct: 493 IPLLIIAFSEMIGVVYVYGIDRFNEDLIFMIGHKPNIF---WQATWRFISPLIMLAIFVF 549



 Score =  112 bits (269), Expect = 3e-23
 Identities = 53/133 (39%), Positives = 72/133 (54%), Gaps = 3/133 (2%)

Query: 18  LSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGL 77
           L  E   +R  W  +  +            NVWRFPYLC ++GGGAF+IPF ++LV  G+
Sbjct: 25  LEVEEAGDRPKWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVFEGI 84

Query: 78  PLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVS 137
           PL+ +E + GQ    G V V+    P   G+G   + VS +V LYYN IIAW ++Y    
Sbjct: 85  PLLHLEFAIGQRLRKGSVGVWRTINPYMLGVGIASMCVSFLVSLYYNTIIAWVMWYF--- 141

Query: 138 FSSIFYQLPWQNC 150
           F+S    LPW  C
Sbjct: 142 FNSFQDPLPWSQC 154


>UniRef50_O44752 Cluster: Sodium:neurotransmitter symporter family
           protein 1; n=2; Caenorhabditis|Rep:
           Sodium:neurotransmitter symporter family protein 1 -
           Caenorhabditis elegans
          Length = 617

 Score =  167 bits (406), Expect = 8e-40
 Identities = 134/543 (24%), Positives = 243/543 (44%), Gaps = 47/543 (8%)

Query: 14  SKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLV 73
           S   L++ +E  R  W  + +F            N    P L   NGG AF   + +++ 
Sbjct: 9   SNLRLTDLVEEWRDLWPSKIEFIVSAMAYLFAMTNFLNLPKLILENGGVAFAAAYAIVVG 68

Query: 74  IAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIV---MLYYNLIIAWT 130
           +  +P M ME+S GQ     PV  +    P+FRG+G   ++ + +V   M  +   +   
Sbjct: 69  VLCMPTMVMEMSIGQVTGRAPVLAFYHLFPVFRGIGVSQILFTMVVLACMTKFLSTLCLF 128

Query: 131 IFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHN 190
           ++Y   +F +    LPW NCKA       +    +  C        + Q  N+  ++   
Sbjct: 129 LYYYFWTFHAGRSGLPWLNCKA-------FPEFVSQPCREAGSITNITQINNRLNTIQAE 181

Query: 191 ITALA-KTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQ 249
            + +   T L RP             S  I +  + +  + +   A W+ +F+ +C GV+
Sbjct: 182 SSMMQFLTTLERP-------------SESIADFKDFQYPILIAQGAIWIAIFVAICFGVR 228

Query: 250 SSGKVVYFTALFPYVVLVILFFRGVTLPGAITGIL--FYLTPDFSQLANAQVWGDAAVQI 307
             GK V F  +  +  L++ F R  TL G +T IL  ++   D+ +LA+ QVW  A  Q 
Sbjct: 229 FVGKTVAFVLMLAFSSLLVFFLRSATL-GGVTEILEIYWKATDWEKLADYQVWRLAIEQA 287

Query: 308 FFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVS 367
                  +G  IT+SSY K SNN   DS+ ++V ++  SF   + I  ++G+L+ +L + 
Sbjct: 288 ILGTGIGYGAFITMSSYMKRSNNLVCDSIFLSVWHLIISFVQTMSIICIVGYLSMKLGIH 347

Query: 368 VDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRF 427
              +++ G    + +    V+ LP   LWS     +LLT+ + + F+++  +  ++L  F
Sbjct: 348 PTELLETGEDQMWYML-AYVSYLP--KLWS----GVLLTICICTMFSVITILALSVLSTF 400

Query: 428 PN-FRQ------KKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGE 480
            + F +      ++ ++   V +F +   + F TN+G +  +L  +     ++  I   E
Sbjct: 401 EDAFGENWSKCCRRFFLALFVCLFCFGLTVYFATNAGRHAYELATRSIKYCTIYFILTAE 460

Query: 481 CILIAWIYGAEKFCGDIQRMI-GRQSKLW--VYLWSAMWRIITPAALVFILVFNWIEYKP 537
               AW Y A K   D+  M+  R    +   +L+      I PA + F+   N ++YK 
Sbjct: 461 LFATAWFYCAHKLGKDLHNMMRSRCCSCFGHFFLYFTYLLPILPAGVAFL---NALDYKF 517

Query: 538 ASY 540
           +S+
Sbjct: 518 SSF 520


>UniRef50_Q695T7 Cluster: Sodium-dependent neutral amino acid
           transporter B(0) (System B(0) neutral amino acid
           transporter) (B(0)AT1); n=36; Euteleostomi|Rep:
           Sodium-dependent neutral amino acid transporter B(0)
           (System B(0) neutral amino acid transporter) (B(0)AT1) -
           Homo sapiens (Human)
          Length = 634

 Score =  165 bits (401), Expect = 3e-39
 Identities = 73/175 (41%), Positives = 111/175 (63%)

Query: 187 VSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCK 246
           ++ N T       R  P + ++  + L +S+ I ++G I+  M +CL  AW ++++C  +
Sbjct: 155 LNENQTGYVDECARSSPVDYFWYRETLNISTSISDSGSIQWWMLLCLACAWSVLYMCTIR 214

Query: 247 GVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQ 306
           G++++GK VY T+  PYVVL I   RG+TL GA  GI+F  TP+ ++LA    W DA  Q
Sbjct: 215 GIETTGKAVYITSTLPYVVLTIFLIRGLTLKGATNGIVFLFTPNVTELAQPDTWLDAGAQ 274

Query: 307 IFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLA 361
           +FF+ S A+GGLI+ SSYN   NNC  DS+IV++ N  TS +  +V++SVIGF A
Sbjct: 275 VFFSFSLAFGGLISFSSYNSVHNNCEKDSVIVSIINGFTSVYVAIVVYSVIGFRA 329



 Score =  139 bits (336), Expect = 2e-31
 Identities = 68/181 (37%), Positives = 109/181 (60%), Gaps = 5/181 (2%)

Query: 354 FSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQF 413
           ++ + F   ++N  +   V+ G GLAFIV+ E +T++P+SPLWS+LFF+ML  LGL S F
Sbjct: 375 YAQLVFQTCDINAFLSEAVE-GTGLAFIVFTEAITKMPLSPLWSVLFFIMLFCLGLSSMF 433

Query: 414 ALMETVTTAILD-RFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWS 472
             ME V   + D R    +  K  +  ++ +  +L G IFT NSG YWL L+D YA +  
Sbjct: 434 GNMEGVVVPLQDLRVIPPKWPKEVLTGLICLGTFLIGFIFTLNSGQYWLSLLDSYAGSIP 493

Query: 473 VLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNW 532
           +LIIA  E   + ++YG ++F  DI+ MIG +  ++   W   WR+++P  ++ I +F +
Sbjct: 494 LLIIAFCEMFSVVYVYGVDRFNKDIEFMIGHKPNIF---WQVTWRVVSPLLMLIIFLFFF 550

Query: 533 I 533
           +
Sbjct: 551 V 551


>UniRef50_Q9H2J7 Cluster: Orphan sodium- and chloride-dependent
           neurotransmitter transporter NTT73; n=70;
           Euteleostomi|Rep: Orphan sodium- and chloride-dependent
           neurotransmitter transporter NTT73 - Homo sapiens
           (Human)
          Length = 730

 Score =  164 bits (398), Expect = 7e-39
 Identities = 75/159 (47%), Positives = 106/159 (66%)

Query: 207 YFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVL 266
           Y+  + L +SS I E+G +   M +CLLAAWV+V L + KG+QSSGK++YF++LFPYVVL
Sbjct: 206 YWYREALNISSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKIIYFSSLFPYVVL 265

Query: 267 VILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNK 326
           +    R   L G+I GI    TP    +   +VW +AA Q+FFAL   +GG+I  SSYNK
Sbjct: 266 ICFLIRAFLLNGSIDGIRHMFTPKLEIMLEPKVWREAATQVFFALGLGFGGVIAFSSYNK 325

Query: 327 FSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELN 365
             NNC+ D+++V+  N  TS  A LV+F+V+GF A+ +N
Sbjct: 326 RDNNCHFDAVLVSFINFFTSVLATLVVFAVLGFKANVIN 364



 Score =  142 bits (345), Expect = 2e-32
 Identities = 67/183 (36%), Positives = 97/183 (53%), Gaps = 5/183 (2%)

Query: 9   GDEEK-SKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIP 67
           G EEK +      E+E ER  W  +  +            NVWRFPYLC  NGGGA+L+P
Sbjct: 43  GQEEKDTDVEEGSEVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLP 102

Query: 68  FTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLII 127
           + ++L++ G+PL F+ELS GQ    G + V+N   P   G+G+   +V   V LYYN+II
Sbjct: 103 YLILLMVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVII 162

Query: 128 AWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSV 187
            W++FY + SF      LPW  C    +  H +   E ++  A    Y+ R+  N S S+
Sbjct: 163 GWSLFYFSQSFQQ---PLPWDQCPLVKNASHTFVEPECEQSSATT-YYWYREALNISSSI 218

Query: 188 SHN 190
           S +
Sbjct: 219 SES 221



 Score =  120 bits (289), Expect = 1e-25
 Identities = 61/173 (35%), Positives = 98/173 (56%), Gaps = 8/173 (4%)

Query: 374 QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK 433
           QG GLAFI + E +T  P SP WS++FF+ML+ LGL S F  +E + T I+D    F+ +
Sbjct: 437 QGTGLAFIAFTEAMTHFPASPFWSVMFFLMLVNLGLGSMFGTIEGIVTPIVD---TFKVR 493

Query: 434 KGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKF 493
           K  +  I  +  +  GLIF   SG Y++ + D Y+A   +LI+ I E I + ++YG +KF
Sbjct: 494 KEILTVICCLLAFCIGLIFVQRSGNYFVTMFDDYSATLPLLIVVILENIAVCFVYGIDKF 553

Query: 494 CGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIE--YKPASYGHYV 544
             D++ M+G     + Y    MW+ I+P  L+ +L+ + +     P  Y  ++
Sbjct: 554 MEDLKDMLGFAPSRYYYY---MWKYISPLMLLSLLIASVVNMGLSPPGYNAWI 603


>UniRef50_Q8ENV8 Cluster: Sodium-dependent transporter; n=18;
           Bacteria|Rep: Sodium-dependent transporter -
           Oceanobacillus iheyensis
          Length = 511

 Score =  161 bits (392), Expect = 4e-38
 Identities = 104/328 (31%), Positives = 170/328 (51%), Gaps = 9/328 (2%)

Query: 205 EEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVV--YFTALFP 262
           E +     L L+    + G +  G+ + L+  WV+V   L +GV+   +V    F  L  
Sbjct: 125 EGFLFGDYLNLAEVPGQVGGLVPGVLIPLIIVWVLVLGILFRGVKKGIEVANRIFIPLLV 184

Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322
            V LVI+  R VTLPGA  G+  + TPDFS++    VW  A  QIFF+LS A+  +IT S
Sbjct: 185 LVFLVIVI-RAVTLPGAAEGLNAFFTPDFSRILEPDVWIAAYGQIFFSLSIAFAIMITYS 243

Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIV 382
           SY    ++   ++ IV   N      AG+ +F V+GF+A    V VD VV  G GLAF+V
Sbjct: 244 SYLPKKSDITNNAFIVGFGNSGFELLAGIGVFGVLGFMATSSGVGVDEVVAGGVGLAFVV 303

Query: 383 YPEVVTRLP-ISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIV 441
           +P ++  LP  + L+  LFFV L   G+ S  ++ E   +A++D+F   R K   V+F  
Sbjct: 304 FPAIINELPAFNGLFGALFFVSLTLAGITSLVSITEAYVSALVDKFKITRTKA--VLFGG 361

Query: 442 AVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMI 501
            +   +  L+F +  G+++L ++D +   + V ++ + E +LIAWI             +
Sbjct: 362 GLAAVI-SLLFASRGGLHFLDVVDYFINQFGVAMLGLVEVVLIAWILRKSNVLKSHANSV 420

Query: 502 GRQSKLWVYLWSAMWRIITPAALVFILV 529
               +L  + W+    +ITP  + ++++
Sbjct: 421 S-DIRLGSW-WTICLTVITPIVMGYMML 446



 Score = 85.0 bits (201), Expect = 5e-15
 Identities = 39/115 (33%), Positives = 62/115 (53%), Gaps = 2/115 (1%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           R  W  R  F            N+WRFP + Y +GGGAF IP+   L+ AG+P++ ME +
Sbjct: 4   RSQWGTRAGFILAAVGSAVGLGNIWRFPSVAYESGGGAFFIPYLFALLTAGIPILIMEFT 63

Query: 86  FG-QYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFS 139
            G +Y    P+  +++       +G+  V+V+ ++  YY++IIAW I Y   SF+
Sbjct: 64  MGHKYRGSAPL-TFSRMNKKAEFVGWWAVLVAFVISTYYSVIIAWAISYSIFSFN 117


>UniRef50_Q1RLZ0 Cluster: Transporter; n=21; Euteleostomi|Rep:
           Transporter - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 660

 Score =  161 bits (391), Expect = 5e-38
 Identities = 71/177 (40%), Positives = 110/177 (62%)

Query: 187 VSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCK 246
           V+ N T L     R  P + ++  + L  S+ IE++G ++  + +CLL AW  +++C  +
Sbjct: 185 VNLNRTGLVSECERSSPVDYFWYRETLNTSTAIEDSGALQWWLVLCLLCAWTFLYICCIR 244

Query: 247 GVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQ 306
           G++++GK VY T+  PYVVL I   R +TL G++ GI F  TPD ++L N   W DA  Q
Sbjct: 245 GIETTGKAVYITSTLPYVVLTIFLIRALTLKGSVNGIKFLFTPDVNELMNPSTWLDAGAQ 304

Query: 307 IFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHE 363
           + F+ S A+GGLI+ SSYN   NNC  D++ +++ N  TS ++  VI+S+IGF A E
Sbjct: 305 VLFSFSLAFGGLISFSSYNSVHNNCEQDAVTISIINGLTSVYSATVIYSIIGFRATE 361



 Score =  130 bits (315), Expect = 8e-29
 Identities = 63/162 (38%), Positives = 99/162 (61%), Gaps = 6/162 (3%)

Query: 374 QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAI--LDRFPNFR 431
           +G GLAFIV+ E +T++P+SPLWS+LFF+ML  LGL + F  +E V   +  L+  P  R
Sbjct: 424 EGTGLAFIVFTEAITKMPVSPLWSVLFFIMLFCLGLSTMFGNIEGVVVPLQDLNLLPK-R 482

Query: 432 QKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAE 491
             K     +  V  +L  L+F  +SG YWL L D +A +  +L+IA+ E I + ++YG +
Sbjct: 483 WPKEVFTGLTCVVSFLTALVFVQSSGNYWLALFDGFAGSIPLLVIALCELIAVVYVYGID 542

Query: 492 KFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWI 533
           +F  DI+ M+G +  ++   W   WR ++P  L+ IL+F +I
Sbjct: 543 RFNEDIKFMVGHKPNIF---WQISWRFLSPVILLVILIFYFI 581



 Score =  115 bits (277), Expect = 3e-24
 Identities = 57/165 (34%), Positives = 87/165 (52%), Gaps = 10/165 (6%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           ER  W  +  +            NVWRFPYLC ++GGGAF+IPF ++LV+ G+PL+ +E 
Sbjct: 61  ERPKWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGVPLLHLEF 120

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
           + GQ    G V V+    P   G+G   ++ S IV +YYN I+AW ++Y+   F+S+   
Sbjct: 121 AIGQRLRSGSVGVWRSISPYLTGVGIASMLASFIVGMYYNTIMAWVMWYL---FNSLQEP 177

Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGT--YYLRQCFNQSYSV 187
           LPW  C    +     S     ECE  +    ++ R+  N S ++
Sbjct: 178 LPWSQCPVNLNRTGLVS-----ECERSSPVDYFWYRETLNTSTAI 217


>UniRef50_Q4SIS1 Cluster: Transporter; n=1; Tetraodon
           nigroviridis|Rep: Transporter - Tetraodon nigroviridis
           (Green puffer)
          Length = 614

 Score =  161 bits (390), Expect = 7e-38
 Identities = 106/353 (30%), Positives = 172/353 (48%), Gaps = 24/353 (6%)

Query: 18  LSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGL 77
           + +E   +R  W  +  +            NVWRFPYLC ++GGGAF+IPF ++LV+ G+
Sbjct: 27  MEKEEAGDRPKWDNKAQYLLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGI 86

Query: 78  PLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVS 137
           PL+ +E + GQ    G   V+    P   G+G   ++VS +V +YYN I+AW ++Y+   
Sbjct: 87  PLLHLEFAIGQRLRKGSTGVWRSINPYLTGIGVASLLVSFLVGMYYNTIMAWIMWYL--- 143

Query: 138 FSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGT---YYLRQCFNQSYSVSHNITAL 194
           F+S    LPW  C    +          +EC A++ T   ++ R+  N S S+  +    
Sbjct: 144 FNSFQDPLPWSQCPLNENRTGL-----VEEC-ARSSTVDYFWYRETLNTSTSIEDSGGLQ 197

Query: 195 AKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKV 254
               L    A   +T   +    GIE +G+    + +     ++++ + L +G+   G V
Sbjct: 198 WWIVLALVAA---WTLLYVCCIRGIETSGK---AVYITSTLPYLVLTIFLVRGLTLKGSV 251

Query: 255 VYFTALF-PYVVLVILFFRGVTLPGAITGILFYLTPDF-----SQLANAQVWGDAAVQIF 308
                LF P V   +   R          +L      F      +L N   W DA  Q+F
Sbjct: 252 EGLKFLFTPKVSACVTRVRHHCWRRHPEALLCETNRAFCSFQVEELINPATWLDAGAQVF 311

Query: 309 FALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLA 361
           ++ S A+GGLI+ SSYN   NNC  D++++++ N  TS ++  VI+S+IGF A
Sbjct: 312 YSFSLAFGGLISFSSYNSVHNNCEQDAVLISIINGCTSVYSATVIYSIIGFRA 364



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 35/85 (41%), Positives = 53/85 (62%), Gaps = 3/85 (3%)

Query: 449 GLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLW 508
           GLIF T SG YWL L D +A +  +L+I   E I + +IYG ++F  DI+ M+G +  ++
Sbjct: 532 GLIFATRSGNYWLALFDNFAGSIPLLVIGFSEMISVIYIYGIDRFNKDIEFMVGHKPNIF 591

Query: 509 VYLWSAMWRIITPAALVFILVFNWI 533
              W   WR I+P  ++FILVF ++
Sbjct: 592 ---WQVTWRFISPLIMIFILVFYFV 613



 Score = 63.7 bits (148), Expect = 1e-08
 Identities = 26/52 (50%), Positives = 37/52 (71%)

Query: 374 QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILD 425
           +G GLAFIV+ E + ++P+SPLW++LFFVML  LGL + F  +E V   + D
Sbjct: 429 EGTGLAFIVFTEAIIKMPVSPLWAVLFFVMLFCLGLSTMFGNIEGVVVPLQD 480


>UniRef50_O45915 Cluster: Transporter; n=2; Caenorhabditis|Rep:
           Transporter - Caenorhabditis elegans
          Length = 673

 Score =  157 bits (382), Expect = 6e-37
 Identities = 122/522 (23%), Positives = 237/522 (45%), Gaps = 33/522 (6%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           E   WT +++             N+W FPYLC    GG F   FT   V   +PL+++E 
Sbjct: 76  EGPTWTSKWEAITATLSFVTCSGNIWFFPYLC-GYYGGWFPYQFTFCYVFIAVPLLYLET 134

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTV---SFSSI 141
           + GQYA+  P++V+++  P   GL  GM  +  +V    +L + W I+ +T+   +  SI
Sbjct: 135 ALGQYASASPLSVFSRMAPAMAGLSAGMCFI--MVFRTISLSV-WAIYDLTIFTHASQSI 191

Query: 142 FYQLPWQNCKAEWSTKHCYSYEEADECE-AQNGTYYLRQCFNQSYSVSHNITALAKTALR 200
           +   PW++C+   S  +C +Y+ + +C   Q G+   ++C    Y     + A      R
Sbjct: 192 WSTSPWESCQESQSGDYCVNYKLSSKCTWIQPGSD--KEC--DEY--QEMLIATRGFQQR 245

Query: 201 RPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGK--VVYFT 258
           + P   +    +   S  + +     +   +C +  W+I+ +    G +  G+  +V  T
Sbjct: 246 KSPFMSFVHGLMYKRSITMNDWEPPSVTSIICAVCLWIIIGIISIGGSKVLGRTGIVALT 305

Query: 259 ALFPYVVLVILFFRGVTLPGAITGILFYLTPDF-SQLANAQVWGDAAVQIFFALSPAWGG 317
            L    ++++ +   +     +    FY +  +  +      W DAA     AL+   GG
Sbjct: 306 LLLVGTIMLLSYGMSLNDTTNVFTAFFYQSEGYEDKWMWVWSWADAAAHALRALNVGCGG 365

Query: 318 LITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIF---SVIGFLAH-ELNVSVDRVVD 373
           +   +S N F N  + D L++++ +       GL+ F   + IG L + +L  S    + 
Sbjct: 366 IQKFASLNNFHNKIHRDVLLISIVSFVFYICTGLLSFMFMAEIGRLYYPDLEASERIQLY 425

Query: 374 QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK 433
               +   V  E++T   +  +W  LF++ L    +    + +  +++ I++R    R+K
Sbjct: 426 ATPVMIESVISEILTNSSMGSIWVFLFWLTLAACSIQGISSYIWVISSMIVERLNGSRRK 485

Query: 434 KG-----W-----VVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECIL 483
            G     W     ++ I++V G +  L F  N G+  +  ++ + A++  + IA  E I 
Sbjct: 486 YGKALASWHKRAIILAIMSVTGLISSLPFLGNGGINLMSSIETF-ASYGTIFIAFVEVIT 544

Query: 484 IAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALV 525
           ++++YG ++F  +I+ MIG      V+ W   W +I+P  L+
Sbjct: 545 VSYVYGFKRFSVNIRAMIGGHGPPNVFWW-LNWLVISPILLI 585


>UniRef50_A4AIT5 Cluster: Transporter; n=1; marine actinobacterium
           PHSC20C1|Rep: Transporter - marine actinobacterium
           PHSC20C1
          Length = 527

 Score =  155 bits (376), Expect = 3e-36
 Identities = 98/329 (29%), Positives = 176/329 (53%), Gaps = 17/329 (5%)

Query: 233 LLAAWVIVFLCL----CKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLT 288
           L+  WV V   L     KGVQ +  +++   L   V  +IL  R + L GA++G+  + T
Sbjct: 170 LVLVWVAVLAVLGSGIAKGVQRAN-IIFLPLLV--VAFLILVVRALFLDGAMSGLNAFFT 226

Query: 289 PDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFF 348
           PDF+ L +  VW  A  QIFF+LS A+G +IT SSY     N    +L+VA +N +    
Sbjct: 227 PDFTALGDPNVWIAAYSQIFFSLSIAFGIMITYSSYRSRKANVTAPALVVAFANSSFEII 286

Query: 349 AGLVIFSVIGFLAHELNVSVDRVVD-QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTL 407
           AG+ +F+ +G+ A +  V++D +    G GL+FI +P +V+++P  P++  LFF  L+  
Sbjct: 287 AGIGVFATLGYFAFQQGVAIDELEGLTGVGLSFITFPAIVSQMPGGPIFGALFFGSLVMA 346

Query: 408 GLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKY 467
           G  S  ++++ V++A  D+F    ++    + + +    +  L+F+T +G+  L  +D++
Sbjct: 347 GFTSLLSVLQVVSSAFQDKFGITARQA--ALRVGSALAIVSVLLFSTTTGLITLDTVDQW 404

Query: 468 AANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWV-YLWSAMWRIITPAALVF 526
           A N  ++  AI   IL+ W++   +   ++   +   S   V  +W  +  ++ P  L++
Sbjct: 405 ANNVGIVGAAIAATILVIWVF---RKGPELAAHLSAVSTFRVGRVWQLLVGVLAPVVLLY 461

Query: 527 ILVFNWIEYKPASYGHYVYPMWADAV-GW 554
           +L+   I     + G+  YP+W  AV GW
Sbjct: 462 MLIQRIIVL--VTEGYEGYPLWYLAVAGW 488



 Score = 89.8 bits (213), Expect = 2e-16
 Identities = 42/117 (35%), Positives = 62/117 (52%), Gaps = 4/117 (3%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           R  WTG+  F            N+WRFP + Y NGGGAFLIP+ + LV AG+P++F++ +
Sbjct: 18  REQWTGQLGFILSAIGSAVGLGNIWRFPGVAYENGGGAFLIPYLIALVTAGIPILFLDYA 77

Query: 86  FG-QYAALGPVA---VYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSF 138
            G ++    P A   +  K       LG+  V +  I+ +YY  ++AW   Y T SF
Sbjct: 78  IGHRFRGSSPTAFRRLGGKAGKWLESLGWFQVWICIIIAVYYAAVVAWAASYFTFSF 134


>UniRef50_O88575 Cluster: Sodium- and chloride-dependent transporter
           XTRP3; n=15; Euteleostomi|Rep: Sodium- and
           chloride-dependent transporter XTRP3 - Mus musculus
           (Mouse)
          Length = 635

 Score =  155 bits (376), Expect = 3e-36
 Identities = 73/175 (41%), Positives = 109/175 (62%)

Query: 187 VSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCK 246
           ++ N T   +   +    + ++  + L +S  I+E G ++   A+CL  AW++V+LC+ +
Sbjct: 171 LNSNHTGYDEECEKASSTQYFWYRKTLNISPSIQENGGVQWEPALCLTLAWLMVYLCILR 230

Query: 247 GVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQ 306
           G +S+GKVVYFT   PY VL+I   RG+TL GA  G+ +  TP   QLAN + W +AA Q
Sbjct: 231 GTESTGKVVYFTTSLPYFVLIIYLVRGLTLHGATNGLAYMFTPKIEQLANPKAWINAATQ 290

Query: 307 IFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLA 361
           IFF+L    GGLI  +SYN+ SN+C   +LIV+V N  T+ F+ +V FS+ GF A
Sbjct: 291 IFFSLGLGCGGLIAFASYNEPSNDCQKHALIVSVINSTTAIFSSIVTFSIYGFKA 345



 Score =  116 bits (279), Expect = 2e-24
 Identities = 58/171 (33%), Positives = 88/171 (51%), Gaps = 10/171 (5%)

Query: 22  IEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMF 81
           +E  R  W     F            NVWRFPYLC   GGG+FL+P+ +ML++ G+PL++
Sbjct: 44  VEKVRPKWDNPLQFLLVCISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLY 103

Query: 82  MELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSI 141
           +EL+ GQ    G +  +    P   G+G   ++VS +  +Y+N+I  W ++Y+  SF   
Sbjct: 104 LELAVGQRMRQGSIGAWRTISPYLSGVGIASLVVSFLASVYFNVINTWALWYLFHSFQD- 162

Query: 142 FYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYL--RQCFNQSYSVSHN 190
              LPW  C    ++ H   Y+E  ECE  + T Y   R+  N S S+  N
Sbjct: 163 --PLPWSVCPL--NSNHT-GYDE--ECEKASSTQYFWYRKTLNISPSIQEN 206



 Score =  116 bits (278), Expect = 3e-24
 Identities = 59/178 (33%), Positives = 96/178 (53%), Gaps = 7/178 (3%)

Query: 362 HELNVSVDRVVD---QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMET 418
           H  N S++  +D   QG GLAFIVY E +  + +S LWS+L+F MLLTLG+ S       
Sbjct: 397 HIRNCSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLTLGMGSMVGTGTA 456

Query: 419 VTTAILD-RFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIA 477
           + T + D +  +    K  +  +V +     G++FT  +G YW  L + Y A  S+L+I 
Sbjct: 457 ILTPLTDSKIISSYLPKEAISGLVCLLNCAIGMVFTMEAGNYWFDLFNDYTATLSLLLIV 516

Query: 478 IGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEY 535
           + E I + ++YG ++F  D++ M GR      + W  MW  ++P  +V + +F   +Y
Sbjct: 517 LVETIAVCYVYGLKRFESDLRAMTGRTLS---WYWKVMWAFVSPLLIVGLFIFYLSDY 571


>UniRef50_Q8BPL9 Cluster: 0 day neonate eyeball cDNA, RIKEN
           full-length enriched library, clone:E130309B01
           product:gamma-aminobutyric acid (GABA-A) transporter 1,
           full insert sequence; n=15; Gnathostomata|Rep: 0 day
           neonate eyeball cDNA, RIKEN full-length enriched
           library, clone:E130309B01 product:gamma-aminobutyric
           acid (GABA-A) transporter 1, full insert sequence - Mus
           musculus (Mouse)
          Length = 256

 Score =  154 bits (373), Expect = 8e-36
 Identities = 83/231 (35%), Positives = 129/231 (55%), Gaps = 33/231 (14%)

Query: 24  PERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFME 83
           P+R  W GRFDF            NVWRFPYLC  NGGGAFLIP+ + L+ AG+PL  +E
Sbjct: 42  PDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLE 101

Query: 84  LSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFY 143
            S GQY ++G + V+ K  P+F+G+G    ++S  + +YY +II+W I+Y+  SF++   
Sbjct: 102 CSLGQYTSIGGLGVW-KLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTT-- 158

Query: 144 QLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPP 203
            LPW+ C   W+T                      +CF+ +YS+  N T +    +    
Sbjct: 159 -LPWKQCDNPWNTD---------------------RCFS-NYSLV-NTTNMTSAVV---- 190

Query: 204 AEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKV 254
             E++   +  ++ G+++ G+IR  +A+ L  AWV+V+ C+ KGV  +GKV
Sbjct: 191 --EFWERNMHQMTDGLDKPGQIRWPLAITLAIAWVLVYFCIWKGVGWTGKV 239


>UniRef50_Q9CMU0 Cluster: Transporter; n=3; Pasteurellaceae|Rep:
           Transporter - Pasteurella multocida
          Length = 502

 Score =  154 bits (373), Expect = 8e-36
 Identities = 102/351 (29%), Positives = 170/351 (48%), Gaps = 11/351 (3%)

Query: 207 YFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSS-GKVVYFTALFPYVV 265
           +F  + L ++ G+    +    +   L+  W+ + + L  GVQ   GK   F      V+
Sbjct: 131 FFFKEYLQMAEGVAVNFDFVASITGPLVGVWIFILVILALGVQKGIGKSATFFMPLLTVM 190

Query: 266 LVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYN 325
            VIL    + LPG+  G+    TPD+S+L    VW  A  QIFF+LS  +G +IT SSY 
Sbjct: 191 FVILVITALFLPGSAKGLNALFTPDWSKLLEPTVWVAAYGQIFFSLSICFGIMITYSSYL 250

Query: 326 KFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPE 385
           K  ++     L+V  +N +    AG+ +F+ +GF+A      V  V   G GLAFI +P 
Sbjct: 251 KKQSDLTGSGLVVGFANSSFELLAGIGVFAALGFMATAAGKEVSEVATSGIGLAFIAFPA 310

Query: 386 VVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAV-F 444
           ++ + P   +  +LFF  LL  G+ S  +++E +  A+ D+    R ++     +  V  
Sbjct: 311 IIDQAPFGSVIGVLFFGSLLFAGITSLMSILEVIIAAVQDK---LRMRRSVATALTCVPM 367

Query: 445 GYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQ 504
             +  L+F T +G+  L ++DK+  ++   I+A+G  ++ A +   E   G    +    
Sbjct: 368 AIVSVLLFGTTTGLPVLDVLDKFVNSFG--IVAVGLMVIYAVLIN-ESLSGLAAHLNETS 424

Query: 505 SKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMW-ADAVGW 554
           S     +W  +   IT   LV++L F  I  K A+ G+  YP W  +  GW
Sbjct: 425 SFKVGVVWRVLIGTITSTVLVYML-FTEIN-KVATEGYGGYPAWFVNTFGW 473



 Score = 93.5 bits (222), Expect = 2e-17
 Identities = 41/115 (35%), Positives = 62/115 (53%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           R  ++GR  F            N+WRFPY+ Y NGGGAF+IP+ V L+ AG+PL+F++ +
Sbjct: 8   RETFSGRKAFIFAAIGSAVGLGNIWRFPYVTYENGGGAFIIPYLVALLTAGIPLLFLDYA 67

Query: 86  FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSS 140
            G      P   + K    F   G+  V+++ I+ +YY +II W   Y   S +S
Sbjct: 68  IGHKYRASPPLAFRKLNKNFETFGWWQVLINVIIGIYYAVIIGWAASYTYFSLNS 122


>UniRef50_UPI0001554745 Cluster: PREDICTED: similar to glycine
           transporter 2a; n=1; Ornithorhynchus anatinus|Rep:
           PREDICTED: similar to glycine transporter 2a -
           Ornithorhynchus anatinus
          Length = 670

 Score =  150 bits (363), Expect = 1e-34
 Identities = 64/134 (47%), Positives = 90/134 (67%), Gaps = 4/134 (2%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           RGNW+ + DF            NVWRFPYL + NGGGAFLIP+ +ML +AGLP+ F+E+S
Sbjct: 325 RGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVS 384

Query: 86  FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQL 145
            GQ+A+ GPV+V+ K  P  +G G  M+I+S ++ +YYN+II +T+FY+  SF S+   L
Sbjct: 385 LGQFASQGPVSVW-KAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSV---L 440

Query: 146 PWQNCKAEWSTKHC 159
           PW +C   W+T  C
Sbjct: 441 PWASCNNPWNTPDC 454



 Score = 72.5 bits (170), Expect = 3e-11
 Identities = 38/158 (24%), Positives = 73/158 (46%), Gaps = 5/158 (3%)

Query: 439 FIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQ 498
           F +  +  L  + FT  +   ++   ++Y     +  I +   +++    G ++FC DI+
Sbjct: 480 FCMTAYPNLTLVNFTNQANKTFVSGSEEYFNLKQIFAIEMINTLVLNDTKGLQRFCEDIE 539

Query: 499 RMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAVGWTXXX 558
            MIG Q  ++   W   W  +TP  L FIL F++ +++P +YG Y YP W+  +GW    
Sbjct: 540 MMIGFQPNIF---WKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLA 596

Query: 559 XXXXXXXXXXXDQICSGPDDLTIMEKARVLARPTEEWG 596
                       ++   P     +E+ +++  P  +WG
Sbjct: 597 CSVIWIPIMFVIKMHLAPG--KFIERLKLVCSPQPDWG 632


>UniRef50_UPI00006611F1 Cluster: Homolog of Homo sapiens "Solute
           carrier family 6 (neurotransmitter transporter,
           dopamine), member 3; n=3; Takifugu rubripes|Rep: Homolog
           of Homo sapiens "Solute carrier family 6
           (neurotransmitter transporter, dopamine), member 3 -
           Takifugu rubripes
          Length = 376

 Score =  147 bits (357), Expect = 7e-34
 Identities = 89/244 (36%), Positives = 132/244 (54%), Gaps = 14/244 (5%)

Query: 253 KVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALS 312
           KV YFTA FPYV+L+IL  RG+TLPGA  GI FYL P    L N ++W +A  QIFF+ S
Sbjct: 135 KVAYFTATFPYVMLLILLIRGLTLPGAFNGIYFYLYPSIEDLTNLKIWIEAGSQIFFSYS 194

Query: 313 PAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVV 372
              G LI LSSYNK++NNCY D   + + N  TSF AG V+FS++GF+A +  V+VD ++
Sbjct: 195 LVTGNLIVLSSYNKYNNNCYRDCFFLCLLNSCTSFLAGFVVFSILGFMAQQQGVTVDALI 254

Query: 373 DQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQ 432
           D  +   F  Y       P   L     FV++ + G+D    +++ +T A    F  F+ 
Sbjct: 255 DNYSASRFYDY----FMAPCECLVISWIFVIIFS-GVDRFMEIIKDMTGA--KPFIIFKL 307

Query: 433 KKGWVVFIVAVFGYLGGLI-FTTNSGMYWLQLMD-KYAANW-----SVLIIAIGECILIA 485
              +++ +V++   +  +I F       W    D  YA  W     +V+++ +   I + 
Sbjct: 308 LWKYIIPLVSLISLILFIINFKQLKINDWYVYPDWAYALGWMMTISTVIMVPLWAIIQMC 367

Query: 486 WIYG 489
           W  G
Sbjct: 368 WTAG 371



 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 36/82 (43%), Positives = 48/82 (58%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           RG W  + ++            NVWRFPYLCY  GGGAFLIP+ ++ V+ G+PL  +E S
Sbjct: 15  RGQWASKTEYILVIAGNVVGLGNVWRFPYLCYRYGGGAFLIPYCLLAVVFGVPLFLLETS 74

Query: 86  FGQYAALGPVAVYNKFCPLFRG 107
            GQ+   G V  + K CPL +G
Sbjct: 75  LGQFTQEGFVTCWRKVCPLAQG 96



 Score = 49.2 bits (112), Expect = 3e-04
 Identities = 35/119 (29%), Positives = 58/119 (48%), Gaps = 12/119 (10%)

Query: 443 VFGYLGGLIFTTNSGMYWLQLMDKYAAN-WSVLIIAIGECILIAWIY-----GAEKFCGD 496
           VF  LG        G+    L+D Y+A+ +    +A  EC++I+WI+     G ++F   
Sbjct: 235 VFSILG--FMAQQQGVTVDALIDNYSASRFYDYFMAPCECLVISWIFVIIFSGVDRFMEI 292

Query: 497 IQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGH-YVYPMWADAVGW 554
           I+ M G +  +   ++  +W+ I P   +  L+   I +K       YVYP WA A+GW
Sbjct: 293 IKDMTGAKPFI---IFKLLWKYIIPLVSLISLILFIINFKQLKINDWYVYPDWAYALGW 348


>UniRef50_UPI00015B5C87 Cluster: PREDICTED: similar to GA18750-PA;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           GA18750-PA - Nasonia vitripennis
          Length = 718

 Score =  147 bits (355), Expect = 1e-33
 Identities = 67/155 (43%), Positives = 98/155 (63%)

Query: 207 YFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVL 266
           ++    L  +  I++   ++  + +CLL +W +VF  + KG+QSSGKVVYFT+LFPY+VL
Sbjct: 214 FWYRTTLDAAPSIDDGQGLKWWIVLCLLLSWFVVFCIMMKGIQSSGKVVYFTSLFPYLVL 273

Query: 267 VILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNK 326
            I F RG+TL GA  G+    TP   +L    VW DAA Q+F++   A+G LI   SYN 
Sbjct: 274 TIFFIRGITLKGADAGLAHMYTPKVEKLLEPTVWLDAATQVFYSFGLAFGSLIAFGSYNT 333

Query: 327 FSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLA 361
             NNC  D ++V+V N  T+ +A +VIF+++GF A
Sbjct: 334 PENNCVRDVILVSVCNAFTAIYASVVIFAILGFKA 368



 Score =  124 bits (298), Expect = 1e-26
 Identities = 56/156 (35%), Positives = 94/156 (60%), Gaps = 3/156 (1%)

Query: 374 QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK 433
           +G GLAFIV+ + +  LP +P WS +FF+MLL LGL SQ  L+E +   + +     R K
Sbjct: 428 EGTGLAFIVFTQAIVELPGAPFWSCIFFLMLLALGLGSQIGLLEGMLCVVFEIDLFKRIK 487

Query: 434 KGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKF 493
           K ++  ++ +F +  GLIF T +G YWL++ D +A    ++++A+ E + + ++YG +KF
Sbjct: 488 KQYITGVLCLFCFFVGLIFCTGAGEYWLKMFDSFAGTIGLVLVALMEMLAVVYVYGHKKF 547

Query: 494 CGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILV 529
             DI+ M G +  L+   W   W+ + P  +V IL+
Sbjct: 548 TQDIEDMTGYRPGLY---WQITWKYLAPVIMVAILI 580



 Score =  120 bits (288), Expect = 2e-25
 Identities = 57/136 (41%), Positives = 76/136 (55%), Gaps = 6/136 (4%)

Query: 18  LSEEIEPERGN---WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVI 74
           L ++ EP++ N   W+G+  F            N+WRFPYLC  NGGGAFLIPF VML++
Sbjct: 62  LQQQPEPKQENRAEWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFLIPFFVMLIL 121

Query: 75  AGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYM 134
            G+PL  +EL  GQ    G + V+N   P   G+G    IV+  V LYYN+II W  +Y+
Sbjct: 122 EGVPLFLIELGLGQRMRQGALGVWNTIHPWLGGIGIASCIVTFFVTLYYNVIITWCFYYL 181

Query: 135 TVSFSSIFYQLPWQNC 150
              F+S    L W  C
Sbjct: 182 ---FNSFREPLLWSEC 194


>UniRef50_A4R7E6 Cluster: Transporter; n=1; Magnaporthe grisea|Rep:
           Transporter - Magnaporthe grisea (Rice blast fungus)
           (Pyricularia grisea)
          Length = 635

 Score =  146 bits (353), Expect = 2e-33
 Identities = 78/262 (29%), Positives = 139/262 (53%), Gaps = 4/262 (1%)

Query: 237 WVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTP-DFSQLA 295
           W +V+LC+  GV  +G+VVYFT   P V+++IL  RG ++  A+ GI  Y+      +L 
Sbjct: 126 WFVVWLCMFSGVGMTGRVVYFTMGMPIVMIIILLGRGASMENAVEGIKLYVAEWHGDKLG 185

Query: 296 NAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFS 355
              +W  AA  IFF++    G   + +SYN+  +N   D+LI+A SN A    AG  +F 
Sbjct: 186 RPAIWQAAASHIFFSIGAGMGYYTSYASYNQKFSNAVQDALIIACSNSAIEVSAGFAVFG 245

Query: 356 VIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFAL 415
           ++G+L   +      V+     LAFI  P    ++P S  W+++FF+ ++ LG  S FA+
Sbjct: 246 IVGYLG--IRPDSGEVLGT-YNLAFITLPAAFVQMPGSNFWAVIFFITIMVLGFSSCFAM 302

Query: 416 METVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLI 475
           +E++ T ++D   + R  +  V  ++ +  +L  L++ T+ G   L  +D + ++ S++ 
Sbjct: 303 LESLVTLVMDTGISKRVSRVAVSTVIIIVSFLLSLMYCTHFGRDLLNAVDAWISDLSLVG 362

Query: 476 IAIGECILIAWIYGAEKFCGDI 497
           I   E ++   +Y      G +
Sbjct: 363 IVALESVVSTTVYRFRDVTGQV 384



 Score = 44.4 bits (100), Expect = 0.009
 Identities = 23/74 (31%), Positives = 39/74 (52%), Gaps = 3/74 (4%)

Query: 74  IAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFY 133
           +  +P++ +E++ GQ    G +  Y+      +GLG  +V+   IV  Y+  I+AW + Y
Sbjct: 5   LLAIPVVILEVAIGQAYRGGCLVAYDHISRRTKGLGLALVMNGYIVCNYFVPILAWVMIY 64

Query: 134 MTVSFSSIFYQLPW 147
              SFS+    LPW
Sbjct: 65  FRHSFSN---PLPW 75


>UniRef50_UPI000023D6A8 Cluster: hypothetical protein FG04240.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG04240.1 - Gibberella zeae PH-1
          Length = 680

 Score =  145 bits (351), Expect = 4e-33
 Identities = 82/263 (31%), Positives = 137/263 (52%), Gaps = 8/263 (3%)

Query: 237 WVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTP-DFSQLA 295
           W +V++ + +G+  +G+VVYFT   P ++ +IL  R V+LP A  GI  Y    +  +LA
Sbjct: 194 WFLVWVSIFRGIGQTGRVVYFTMSLPVILTIILVGRSVSLPNAGRGIKLYFGEWNGDKLA 253

Query: 296 NAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFS 355
           + ++W  AA Q+FF+    +G   + +SYN+  +N  +DS ++  SN+    FA    F 
Sbjct: 254 SGEIWQTAAGQVFFSTGVGFGYFSSYASYNQKHSNAVMDSCLIVGSNVIFEGFAAFAAFG 313

Query: 356 VIGFLAHELNVSVDRVVDQGA-GLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFA 414
           V+GFL     V  +R+   GA  + F+  P  +T+LP S  W+   F  L+ LG  S FA
Sbjct: 314 VVGFLG-MAPVENERI---GAFTIGFLTLPTAITQLPGSSFWAFALFFTLVVLGYSSAFA 369

Query: 415 LMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVL 474
           +++ V T I+D  P  R++  WVV  + V  +L  L + T  G   L  +D++  + +++
Sbjct: 370 MLDAVVTLIMDTKPRIRRE--WVVTGLVVVSFLISLPYCTQFGYALLTGVDRWINDVALV 427

Query: 475 IIAIGECILIAWIYGAEKFCGDI 497
            +   EC      Y      G +
Sbjct: 428 FVVFSECAFSTTFYRWRDVAGQV 450



 Score = 72.5 bits (170), Expect = 3e-11
 Identities = 35/139 (25%), Positives = 65/139 (46%), Gaps = 3/139 (2%)

Query: 16  APLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIA 75
           +P   + +  R +W  R  F            N+ R+P   YNN G  + IP+ + + + 
Sbjct: 15  SPPPSKAQDGRESWNSRASFLLAAMGGCAGMGNLIRYPSQVYNNNGLQWFIPYLMCVFLI 74

Query: 76  GLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMT 135
            +P + +E+S GQ    G V  +N      +G+G+ ++ +  +V  Y+ + ++W + Y  
Sbjct: 75  AIPALILEVSIGQAYRGGSVVAFNNINHRLKGMGFSLLYIGFMVTPYFVVNLSWIMIYFR 134

Query: 136 VSFSSIFYQLPWQNCKAEW 154
            SF S    LPW+    E+
Sbjct: 135 NSFQS---PLPWEGRAEEY 150


>UniRef50_A5UNF8 Cluster: Na+-dependent transporter, SNF family;
           n=2; Methanobrevibacter smithii ATCC 35061|Rep:
           Na+-dependent transporter, SNF family -
           Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM
           861)
          Length = 498

 Score =  144 bits (350), Expect = 5e-33
 Identities = 100/332 (30%), Positives = 165/332 (49%), Gaps = 17/332 (5%)

Query: 207 YFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLC----LCKGVQSSGKVVYFTALFP 262
           YFT   L  +  +   G     +A+ +L  WVI+++     L KG+    KV+    LF 
Sbjct: 130 YFTGSFLQANDTLGGLGTFVPFVAIAMLVGWVIMWVISHTDLEKGLGRVSKVLV-PLLFA 188

Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322
            ++ ++LF   +TLPGA  G+     PD+S L N  +W  A  Q+ F+LS       T +
Sbjct: 189 IMIFIVLF--SLTLPGAGIGLAELYNPDWSLLLNFNIWMAAFGQMIFSLSLGMSIAFTYA 246

Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIV 382
           SY K  ++   ++L V V+N     FA + +FS++G+++ +  V+V  +V QG GL FIV
Sbjct: 247 SYTKDDSDLVSNALWVTVANCGFENFAAIGVFSILGYMSLQSGVAVPDLVTQGTGLVFIV 306

Query: 383 YPEVVTRL-PISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIV 441
           YP V   L   + +   LFF  +   GL S  + +E ++ +I ++F   R K    + I+
Sbjct: 307 YPTVFNVLGDWASVIGPLFFFTVYLAGLTSILSTIEPLSFSIQNKFGWSRNK---TMTIL 363

Query: 442 AVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMI 501
            VFG    +I+ T  G Y L + D +    ++LI  I ECI+ AWI+ AE     I ++ 
Sbjct: 364 CVFGAAVSMIYATAMGSYILGIADTFVNQIAILIGVIFECIIFAWIFKAENI---IPKLN 420

Query: 502 GRQSKLWVYLWSAMWRIITPAALVFILVFNWI 533
            +   + +  W   W ++    L   +   W+
Sbjct: 421 AKSKSIKLGKW---WLVVVKYVLPIFIAIVWV 449



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 34/114 (29%), Positives = 60/114 (52%), Gaps = 2/114 (1%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           ++  W     F            N+WR+PY+ Y+NGGGAF IP+ V ++I G+P + +E 
Sbjct: 6   DKNEWGSNLSFLLAMIGSAVGLGNIWRYPYVLYSNGGGAFFIPYIVAILIMGIPFLILEY 65

Query: 85  SFG-QYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVS 137
             G  + +  P AV       +  LG+ + +   ++++YY+ I+ W  FY+ +S
Sbjct: 66  GVGYNFKSSFPKAV-KSISKKWEYLGWFLPVAVFMILIYYSAILGWDGFYVIIS 118


>UniRef50_Q2NGG4 Cluster: Predicted Na+-dependent transporter; n=1;
           Methanosphaera stadtmanae DSM 3091|Rep: Predicted
           Na+-dependent transporter - Methanosphaera stadtmanae
           (strain DSM 3091)
          Length = 491

 Score =  144 bits (349), Expect = 6e-33
 Identities = 94/314 (29%), Positives = 168/314 (53%), Gaps = 19/314 (6%)

Query: 208 FTNQVLGLSSGIEETG--EIRLGMAMCLLAAWVIVFLC----LCKGVQSSGKVVYFTALF 261
           F N V+ L S  + +G   I + + + L   W+I++      + KG+    K++  T L 
Sbjct: 130 FLNTVI-LESTTDVSGLFHIAIYVLIALTIVWIILWYISHHDINKGIGKFNKIL--TPLL 186

Query: 262 PYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITL 321
            +++++I+    +TLPG+  G+L  LTPD S + N+ +W  A  QI F+LS     ++  
Sbjct: 187 -FIIMIIIVAFALTLPGSGFGVLTLLTPDLSAITNSDIWIAALSQILFSLSIGMCIVVAY 245

Query: 322 SSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFI 381
           ++Y     N   + L+VA++N +   F  + IF ++GF++    + ++ +V QG  LAF+
Sbjct: 246 TAYLPDDVNIPKNVLLVALANSSFEVFTAIGIFGILGFMSTTHGIPINELVTQGTTLAFV 305

Query: 382 VYPEVVTRLP-ISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFI 440
            +P++   +  I  +   LFF+ LL  G+ S  ++ME +  ++ D+F  F +KK   V I
Sbjct: 306 AFPQIFNVMGFIGYIIGPLFFIALLFAGITSNISIMEPIILSLRDKF-GFERKK--AVTI 362

Query: 441 VAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQR- 499
             V G++  L+FTT+ G   + + D +   + V++  I E ILI WIYG +K    I + 
Sbjct: 363 CCVVGFIISLLFTTSLGSSLVGVFDTFINQFGVVLNVIIELILITWIYGIDKILPGINKN 422

Query: 500 ----MIGRQSKLWV 509
                IG + K+W+
Sbjct: 423 ATFLKIGPKWKIWM 436



 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 31/110 (28%), Positives = 56/110 (50%)

Query: 29  WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQ 88
           W     F            N+WR+PY+ Y NGGGAF++P+ + ++  G+PL+F+E   G 
Sbjct: 10  WESNISFILAMIGSAVGLGNIWRYPYVAYTNGGGAFILPYIISIICLGIPLLFIEYGTGY 69

Query: 89  YAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSF 138
               G   +  K    +  +G+ +   +  ++ YY  ++AW + Y+ +SF
Sbjct: 70  KFKSGMSKILRKINTKYEYIGWFIQTSTFFILTYYVCVVAWNLLYVPLSF 119


>UniRef50_UPI0000DB790B Cluster: PREDICTED: similar to CG5549-PA;
           n=1; Apis mellifera|Rep: PREDICTED: similar to CG5549-PA
           - Apis mellifera
          Length = 174

 Score =  143 bits (347), Expect = 1e-32
 Identities = 63/141 (44%), Positives = 88/141 (62%), Gaps = 3/141 (2%)

Query: 21  EIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLM 80
           E +PERG+W+   +F            NVWRFPYL Y NGGGAF+IPF +ML+  GLP+ 
Sbjct: 26  EQDPERGSWSNPIEFVLSCIGYAVGIGNVWRFPYLVYRNGGGAFIIPFVLMLITMGLPIF 85

Query: 81  FMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSS 140
           F+EL+ GQY+ LGP   + +  P   GLGY  +IV  +VM+YY +I+AWT+FY   +F S
Sbjct: 86  FLELAVGQYSGLGPNEAFKRMAPALEGLGYCTLIVILLVMVYYMVIVAWTLFY---TFLS 142

Query: 141 IFYQLPWQNCKAEWSTKHCYS 161
              +L W  C  +++T   Y+
Sbjct: 143 FLPKLSWAYCDNDFNTNREYT 163


>UniRef50_P44849 Cluster: Uncharacterized sodium-dependent
           transporter HI0736; n=30; Bacteria|Rep: Uncharacterized
           sodium-dependent transporter HI0736 - Haemophilus
           influenzae
          Length = 508

 Score =  143 bits (346), Expect = 1e-32
 Identities = 97/326 (29%), Positives = 159/326 (48%), Gaps = 14/326 (4%)

Query: 233 LLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLV--ILFFRGVTLPGAITGILFYLTPD 290
           L+A W++    L  GVQ  G     + L P +V++  +L    + LPGA  G+    TPD
Sbjct: 161 LIAMWIVALGVLSMGVQK-GIAKVSSVLMPVLVVMFMVLVIYSLFLPGAAKGLDALFTPD 219

Query: 291 FSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAG 350
           +S+L+N  VW  A  QIFF+LS  +G ++T +SY K  ++     L+V  +N +    AG
Sbjct: 220 WSKLSNPSVWIAAYGQIFFSLSIGFGIMVTYASYLKKESDLTGSGLVVGFANSSFEVLAG 279

Query: 351 LVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLD 410
           + +F+ +GF+A      V  V   G GLAF  +P ++ + P   +  +LFF  L    L 
Sbjct: 280 IGVFAALGFIATAQGQEVSEVAKGGIGLAFFAFPTIINKAPFGEVLGMLFFGSLTFAALT 339

Query: 411 SQFALMETVTTAILDRFPNFRQKKGWVVFIVAV-FGYLGGLIFTTNSGMYWLQLMDKYAA 469
           S  +++E + +AI D+    R  +G V FIV V    +  ++F T +G+  L + DK+  
Sbjct: 340 SFISVIEVIISAIQDK---IRISRGKVTFIVGVPMMLVSVILFGTTTGLPMLDVFDKFVN 396

Query: 470 NWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILV 529
            + ++ +A    I I     A +  G +   +   S   V  +  +  ++T   L F+L 
Sbjct: 397 YFGIVAVAFASLIAIV----ANEKLGLLGNHLNETSSFKVGFFWRLCIVLTSGVLAFMLF 452

Query: 530 FNWIEYKPASYGHYVYPMW-ADAVGW 554
                 K  S G+  YP W  +  GW
Sbjct: 453 SEGA--KVFSEGYEGYPNWFVNTFGW 476



 Score = 96.3 bits (229), Expect = 2e-18
 Identities = 42/122 (34%), Positives = 66/122 (54%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           +R  ++GR  F            N+WRFPY  Y NGGGAF+IP+ + L+ AG+PL+F++ 
Sbjct: 10  KRETFSGRRAFILAAIGSAVGLGNIWRFPYTTYENGGGAFIIPYLIALLTAGIPLLFLDY 69

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
           + G     G    Y +F P F   G+  ++V+ I+ LYY +++ W   Y   SF+  +  
Sbjct: 70  AIGHRHRGGAPLSYRRFSPHFEVFGWWQMMVNVIIGLYYAVVLGWAASYTYFSFTGAWGD 129

Query: 145 LP 146
            P
Sbjct: 130 KP 131


>UniRef50_A7BDH7 Cluster: Putative uncharacterized protein; n=1;
           Actinomyces odontolyticus ATCC 17982|Rep: Putative
           uncharacterized protein - Actinomyces odontolyticus ATCC
           17982
          Length = 528

 Score =  141 bits (342), Expect = 4e-32
 Identities = 94/317 (29%), Positives = 166/317 (52%), Gaps = 14/317 (4%)

Query: 233 LLAAWVIVFLC----LCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLT 288
           L   WV+V       L KGV+++ KV     +  ++ LV+   R + LPGA+ G+  + T
Sbjct: 162 LALVWVLVLFVIGRGLSKGVEAANKVFLPLLVILFLALVV---RALFLPGAVEGLNAFFT 218

Query: 289 PDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFF 348
           P++S LA+  VW  A  QIF++LS  +G ++T +SY K  +N    +L+   +N +    
Sbjct: 219 PNWSALADPNVWLAAFAQIFYSLSVGFGIMLTYASYLKPKSNLTGTALVAGFANSSFEIL 278

Query: 349 AGLVIFSVIGFLAHELNVSVDRVVD-QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTL 407
           AG+ +FS IGF+AH+  VSV  V    G  L+F+ +P++++ +P  PL+ +LFF  L+  
Sbjct: 279 AGIGVFSAIGFMAHQGGVSVSEVEGLTGPILSFVTFPKIISMMPGGPLFGVLFFSSLVLA 338

Query: 408 GLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKY 467
           G+ S  +L++ V+  + D+F     +   V+ + A    +  ++F T SG+  L ++D +
Sbjct: 339 GVTSLLSLLQVVSGGLQDKFGWSPARSALVLGVPAT--VISLVLFGTRSGLNNLDIVDNF 396

Query: 468 AANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWV-YLWSAMWRIITPAALVF 526
             +  V+  AI   +L A + G     G ++  I   S + V  LW  +  I+ P  L  
Sbjct: 397 INSVGVVSSAIMFAVLCA-VAGPR--LGVLRAHINSVSSVKVPKLWEPLVGIVIPVVLFV 453

Query: 527 ILVFNWIEYKPASYGHY 543
           ++  + ++     Y  Y
Sbjct: 454 MMAMSIVQVLKQGYESY 470



 Score = 82.2 bits (194), Expect = 4e-14
 Identities = 35/112 (31%), Positives = 58/112 (51%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           R +W+G+  F            N+WRFP + Y+NGGGAFL+P+ V LV  G+P+++++ +
Sbjct: 13  RDSWSGQTGFLLAAIGSAIGLGNIWRFPGVSYSNGGGAFLVPYLVALVFVGIPMLWLDYA 72

Query: 86  FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVS 137
            G      P     K       +G+    V  ++M+YY  ++AW + Y   S
Sbjct: 73  VGHKFRGSPPWALRKIIGGGEFVGWFQTFVCFVIMVYYGAVLAWGVQYTIYS 124


>UniRef50_UPI0001556266 Cluster: PREDICTED: similar to Solute
           carrier family 6 (neurotransmitter transporter,
           betaine/GABA), member 12, partial; n=1; Ornithorhynchus
           anatinus|Rep: PREDICTED: similar to Solute carrier
           family 6 (neurotransmitter transporter, betaine/GABA),
           member 12, partial - Ornithorhynchus anatinus
          Length = 219

 Score =  140 bits (340), Expect = 8e-32
 Identities = 63/120 (52%), Positives = 83/120 (69%)

Query: 254 VVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSP 313
           VVYFTA FPY++L+IL  RGVTLPGA  GI++YL PD  +LA+ QVW DA  QIFF+ + 
Sbjct: 1   VVYFTATFPYLMLIILLVRGVTLPGASQGIVYYLKPDVQRLADPQVWMDAGTQIFFSFAI 60

Query: 314 AWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVD 373
             G L  L SYNK+ NNCY D + + + N +TSF AG  +FS++GF+A E  V +  V +
Sbjct: 61  CQGCLTALGSYNKYHNNCYRDCIALCILNSSTSFVAGFAVFSILGFMAQEQGVPISEVAE 120


>UniRef50_Q0PHT6 Cluster: High-affinity dopamine transporter
           protein; n=2; Arthropoda|Rep: High-affinity dopamine
           transporter protein - Limulus polyphemus (Atlantic
           horseshoe crab)
          Length = 250

 Score =  138 bits (333), Expect = 5e-31
 Identities = 63/152 (41%), Positives = 89/152 (58%), Gaps = 5/152 (3%)

Query: 51  RFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGY 110
           RFPYLCY NGGGAFL+P+ +ML + G+PL +MEL+ GQY   G +  + +  PL +G+GY
Sbjct: 1   RFPYLCYKNGGGAFLVPYLIMLAVGGIPLFYMELALGQYHRQGAITCWGRLVPLLKGVGY 60

Query: 111 GMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEA 170
            +++++  V  YYN+IIAW + Y   SF+S   +LPW  C   W+T  C     + E E 
Sbjct: 61  AVILIAFYVDFYYNVIIAWALHYFFASFTS---ELPWTRCNNTWNTPECVGLAISKESEF 117

Query: 171 QNGTYYLRQCFNQSYSVSHNITALAKTALRRP 202
            N    L   FN S  V   +T   K ++R P
Sbjct: 118 SNNETSL-DWFNFS-EVITEVTNWTKNSIRTP 147



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 25/70 (35%), Positives = 38/70 (54%), Gaps = 2/70 (2%)

Query: 185 YSVSHNITALAKTALRRPPAEEYFTNQVLGL--SSGIEETGEIRLGMAMCLLAAWVIVFL 242
           ++ +  +  L K       A EYF   +L L  S GIE  G ++  MA+CLLA ++I + 
Sbjct: 181 FNNTDTVAILRKRNQGASSAAEYFNRGLLELHKSGGIENLGIVKWDMALCLLAVYLICYF 240

Query: 243 CLCKGVQSSG 252
            L KG+ +SG
Sbjct: 241 SLWKGISTSG 250


>UniRef50_Q0PHU0 Cluster: High-affinity dopamine transporter
           protein; n=4; Mandibulata|Rep: High-affinity dopamine
           transporter protein - Spirostreptus sp. CD-2006
          Length = 224

 Score =  137 bits (332), Expect = 7e-31
 Identities = 84/227 (37%), Positives = 118/227 (51%), Gaps = 28/227 (12%)

Query: 51  RFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGY 110
           RFPYLCY NGGGAFLIP+ +ML I G+PL +MEL+ GQY   G +  + +  PLF+G+GY
Sbjct: 1   RFPYLCYKNGGGAFLIPYIIMLCIGGIPLFYMELALGQYHRKGAITCWGRLVPLFKGIGY 60

Query: 111 GMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIF----YQLPWQ--NCK------------- 151
            +V+++  V  YYN+IIAW + Y   SF+S         PW   +C+             
Sbjct: 61  AVVLIAFYVDFYYNVIIAWALHYFFASFASELPWTKCNNPWNTPDCQEIGSSPLQPPRND 120

Query: 152 --AEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRP--PAEEY 207
             + WST    S E   +      T+              N T + +  L R   PA EY
Sbjct: 121 AISNWSTPWSPSSESFLDYA---WTFTESTLDGVDIRQDTNATTVLEMDLTRKSSPAAEY 177

Query: 208 FTNQVLGL--SSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSG 252
           F    L L  SSGI + G ++  MA+CLLA ++I +  + KG+ +SG
Sbjct: 178 FNRAFLELHKSSGIGDLGYVKWDMALCLLAVYLICYFSMWKGISTSG 224


>UniRef50_Q2NGB7 Cluster: Predicted Na+-dependent transporter; n=2;
           Methanobacteriaceae|Rep: Predicted Na+-dependent
           transporter - Methanosphaera stadtmanae (strain DSM
           3091)
          Length = 497

 Score =  136 bits (329), Expect = 2e-30
 Identities = 74/279 (26%), Positives = 147/279 (52%), Gaps = 8/279 (2%)

Query: 237 WVIVFLCLCKGVQSS-GKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLA 295
           W+ ++L   K +++  GKVV  T      ++ ++     TL G + G+     PD+S L 
Sbjct: 168 WIFLWLVSRKNIENGIGKVVKITIPSLICIMFLIVAYSFTLNGHMIGLTNLFNPDWSALL 227

Query: 296 NAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDS-LIVAVSNIATSFFAGLVIF 354
           N+ +W  A  Q+ F+LS      +T +SY   +N+  +DS L+VA SN +      + +F
Sbjct: 228 NSDIWLAAFTQVLFSLSVGQSIALTYASYLD-NNDHLVDSVLVVAASNSSFEIITAIGVF 286

Query: 355 SVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRL-PISPLWSILFFVMLLTLGLDSQF 413
           +++GF++ +  + ++++   G GL F+V+PE+   +  ++ +    FF+ +   G+ + F
Sbjct: 287 NILGFMSLKTGLGIEQIATSGTGLIFVVFPEIFNIMGDVAYIIGPAFFLCVFFAGVTTMF 346

Query: 414 ALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSV 473
           A +E ++ ++  +F   R K      IV  FG+L  +IFTT +G Y L + D++   + +
Sbjct: 347 AFIEPMSLSLAKKFKMSRSK---TATIVCFFGFLTSIIFTTGAGNYILAIADEFINQYGI 403

Query: 474 LIIAIGECILIAWIYGAEKFCGDI-QRMIGRQSKLWVYL 511
           L   + + I+  W+YG +K    + ++ I      W+++
Sbjct: 404 LFAILLQAIIFGWLYGIDKLVPILNEKSIVHIGSKWIWI 442



 Score = 78.2 bits (184), Expect = 6e-13
 Identities = 33/115 (28%), Positives = 55/115 (47%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           E   W     F            N+WRF Y+ Y+NGGG+F IP+   ++  G+P + +E 
Sbjct: 14  EAYKWGSNISFLFAMIGAAIGLGNIWRFSYIVYSNGGGSFFIPYIFAILTLGVPFLILEY 73

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFS 139
             G        ++     P F  +G+ +V +  +VM YY +II W + Y+ + F+
Sbjct: 74  GLGVKHRDSLSSILKNLNPKFEVIGWFIVFLVFLVMTYYIVIIGWDVIYLLLGFT 128


>UniRef50_A7RHB6 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 318

 Score =  135 bits (326), Expect = 4e-30
 Identities = 90/318 (28%), Positives = 153/318 (48%), Gaps = 36/318 (11%)

Query: 48  NVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQ-YAALGPVAVYNKFCPLFR 106
           NV RF  LC+ +GG AF IP+ +ML++ G PL+ +E++ GQ +     V  +    P   
Sbjct: 28  NVVRFSQLCHKHGGVAFFIPYILMLMLEGTPLLCLEMAVGQRFGKKSLVQAWGDLKPNLS 87

Query: 107 GLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEAD 166
           GLG   +I ++IV+ YYN+++ W ++Y   S       L W+ C    S +   + +  +
Sbjct: 88  GLGLAAIIENTIVLFYYNVLVTWCLYYFVQSLRG---TLIWEPCGITSSVQGNQTSQIVE 144

Query: 167 -ECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEI 225
            EC       Y    + +S ++S +I +                      SSG      +
Sbjct: 145 TECAKAGAEKYF--WYRKSLNISDDINS----------------------SSG------V 174

Query: 226 RLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGI-L 284
            + M + +  AW   +L   +G++ S K+++   +   V  VI FF  V L G   G+ L
Sbjct: 175 NMFMYLFVFMAWTSAWLLSMRGIRRSSKLMWLILVLIVVEFVIFFFFAVDLKGWTYGLSL 234

Query: 285 FYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIA 344
            +       L +  VW DAA QIF+++   +G  I  SS N   NN + D+++ +++N  
Sbjct: 235 LFSFDRLDTLKSIDVWLDAAGQIFYSMGIGYGSNILFSSGNNHDNNLFSDAIVCSLANSG 294

Query: 345 TSFFAGLVIFSVIGFLAH 362
           TS +A +++FS  G+ AH
Sbjct: 295 TSIWASIIMFSFFGYRAH 312


>UniRef50_UPI0000E816B2 Cluster: PREDICTED: similar to solute
           carrier family 6 (neurotransmitter transporter), member
           17; n=1; Gallus gallus|Rep: PREDICTED: similar to solute
           carrier family 6 (neurotransmitter transporter), member
           17 - Gallus gallus
          Length = 521

 Score =  133 bits (322), Expect = 1e-29
 Identities = 60/132 (45%), Positives = 77/132 (58%), Gaps = 4/132 (3%)

Query: 20  EEIEPE-RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLP 78
           EE++ E R  W  +  +            NVWRFPYLC  NGGGA+L+P+ V+L+I GLP
Sbjct: 53  EELDAENRPAWNSKLQYILAQIGYSVGLGNVWRFPYLCQKNGGGAYLVPYLVLLIIIGLP 112

Query: 79  LMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSF 138
           L F+EL+ GQ    G + V+N  CP   G+GY   +V   V LYYN+II W+IFY    F
Sbjct: 113 LFFLELAVGQRIRRGSIGVWNYICPRLGGIGYASCLVCFFVGLYYNVIIGWSIFYF---F 169

Query: 139 SSIFYQLPWQNC 150
            S  Y LPW  C
Sbjct: 170 KSFQYPLPWSEC 181



 Score =  121 bits (292), Expect = 5e-26
 Identities = 55/113 (48%), Positives = 78/113 (69%)

Query: 253 KVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALS 312
           +V+YF++LFPYVVLV    RG+ L GA+ GI+   TP   ++ + QVW +AA Q+FFAL 
Sbjct: 221 EVMYFSSLFPYVVLVCFLVRGLLLRGAVDGIMHMFTPKLDKMLDPQVWREAATQVFFALG 280

Query: 313 PAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELN 365
             +GG+I  SSYNK  NNC+ D+ +V+  N  TS  A LV+F+V+GF A+ +N
Sbjct: 281 LGFGGVIAFSSYNKQDNNCHFDATLVSFINFFTSVLATLVVFAVLGFKANIMN 333



 Score =  107 bits (258), Expect = 7e-22
 Identities = 55/139 (39%), Positives = 80/139 (57%), Gaps = 4/139 (2%)

Query: 354 FSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQF 413
           F  +G  A  L   +D+ V QG GLAFI + E +T  P SP WS++FF+ML+ LGL S  
Sbjct: 387 FKELGLDACLLEDELDKSV-QGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMI 445

Query: 414 ALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSV 473
             M  +TT I+D    F+ +K        +F ++ GLIF   SG Y++ + D Y+A   +
Sbjct: 446 GTMSGITTPIID---TFKVRKEVFTVGCCIFAFVVGLIFVQRSGNYFVTMFDDYSATLPL 502

Query: 474 LIIAIGECILIAWIYGAEK 492
            ++ I E I +AWIYG +K
Sbjct: 503 TVVVILENIAVAWIYGTKK 521


>UniRef50_Q0UQY0 Cluster: Transporter; n=1; Phaeosphaeria
           nodorum|Rep: Transporter - Phaeosphaeria nodorum
           (Septoria nodorum)
          Length = 681

 Score =  133 bits (321), Expect = 2e-29
 Identities = 81/271 (29%), Positives = 135/271 (49%), Gaps = 12/271 (4%)

Query: 239 IVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGI-LFYLTPDFSQLANA 297
           +V+LC+ +G   +G+VVYFT   P +V+VIL  RG +LP A  GI L++ T     L+  
Sbjct: 186 LVWLCIFRGTGWTGRVVYFTMGMPLIVIVILIGRGASLPNAGRGIRLYFATWRSEALSGT 245

Query: 298 QVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVI 357
            +W DA  Q+F++    +G     +SYN    N   D++I+  +N           F ++
Sbjct: 246 GIWQDAVGQVFYSTGVGFGFYTAYASYNHQFANAAQDAVILVFTNAFLEASLAFAAFGIV 305

Query: 358 GFLAHELNVSVDRVVDQGA-GLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALM 416
           GF    + ++ D     G+  L F+ YPE    +P S  WS LFF+ L  +G+ S F ++
Sbjct: 306 GF----MGMTPDPENPMGSYSLGFMTYPEAFVHMPGSNFWSALFFLTLAVVGVSSTFVML 361

Query: 417 ETVTTAILD-RFPNFRQ-KKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVL 474
           +   T I+D  F   R+  + WV  ++    +L  L   T  G Y+L  +D++  N  ++
Sbjct: 362 DAFMTLIMDSAFARTRRWTRTWVATVLVFVVFLLSLPNCTQFGYYYLDGIDRWINNVGLV 421

Query: 475 IIAIGECILIAWIYGAEKFCGDIQRMIGRQS 505
            +   EC+    +Y  E    D+   +G Q+
Sbjct: 422 FVVWAECVSATTVYRFE----DVVDQVGLQA 448



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 40/132 (30%), Positives = 61/132 (46%), Gaps = 3/132 (2%)

Query: 16  APLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIA 75
           AP  ++    R  W  R  F            N  R+P   +NN G  + IP+ + LV+ 
Sbjct: 12  APPPQKAADGRDQWPSRTAFILASLSGVIGMGNFLRYPSTVFNNHGLQWFIPYLLALVLL 71

Query: 76  GLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMT 135
            +P + +EL+ G     G V  +NK     RG G+ +  V  +V +Y+  IIAW + +  
Sbjct: 72  AVPALALELAAGNAYRGGTVTAFNKISRRMRGTGFALNYVGLVVSIYFIPIIAWGMVFFQ 131

Query: 136 VSFSSIFYQLPW 147
            SF+S    LPW
Sbjct: 132 KSFTS---PLPW 140


>UniRef50_Q9VLY3 Cluster: Transporter; n=6; Drosophila
           melanogaster|Rep: Transporter - Drosophila melanogaster
           (Fruit fly)
          Length = 596

 Score =  132 bits (319), Expect = 3e-29
 Identities = 127/520 (24%), Positives = 234/520 (45%), Gaps = 35/520 (6%)

Query: 17  PLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAG 76
           P S ++   RG W    DF            +V+   +  + + G   ++P+ V + I  
Sbjct: 13  PFSPDLN--RGKWDKPTDFMFACFGLALKL-DVFVASFWMFFDMGILGILPYFVYMSIYL 69

Query: 77  LPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTV 136
           +P+M +    GQ+++ G ++ + +  P F+G+GY    ++  +++YY++  A  + ++  
Sbjct: 70  VPIMVIHSFMGQFSSSGFISAF-RLSPFFKGMGYVSGFLTISMLIYYSIFAAVPLLFIIN 128

Query: 137 SFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAK 196
           SF      LPW +C+   S+ H  S   +  C   N T  L   F++ Y+ SH +  +  
Sbjct: 129 SFRPT---LPW-SCEG-LSSWHNGSATLSSSC---NKTLILED-FSE-YNRSHQLLHVPS 178

Query: 197 TALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSS--GKV 254
               +     Y + Q   +    ++  E+           WV++     K  +++  GK+
Sbjct: 179 VLYFQ---NHYDSMQQDAVPDWYKDY-ELSWHFVGLFAIIWVVIAFIFYKFSETAKFGKL 234

Query: 255 VYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPA 314
           + +  +   V+L++ F R + LPGA+ G+  Y+TP  S +A   V     + +  A    
Sbjct: 235 IRYMVIVTLVLLLVCFVRFLFLPGALNGLHRYVTPKASDMAMGVV--STFIMVLHAFGAG 292

Query: 315 WGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVS-VDRVVD 373
           WG +ITLSS+N F  +    S I++   I      G+V F     L H  N + +  V D
Sbjct: 293 WGSVITLSSFNGFKTDIMSYSWIISFGQIFIYIMFGMVSF----MLEHYFNGNKLSDVDD 348

Query: 374 QGAGLA-FIVY---PEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPN 429
            G  L+ +++Y      ++ +    LW+ +++ MLL   L      + TV  ++ D F  
Sbjct: 349 NGHVLSHWLLYLSSASALSTMAWPNLWTFIYYSMLLIAALIVMTTQIFTVLQSLFDEFEV 408

Query: 430 FRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYG 489
            R +K  V F +     L    F TN G+ +   +    A +S  ++ +   +++ WIYG
Sbjct: 409 LRVRKQEVTFGLIGGIALCSFYFCTNHGIIFFSALG-LDAIFSHSLLHLLLLLVVLWIYG 467

Query: 490 AEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILV 529
            E+F  DI+ M+G+    W      + R I P  LV  L+
Sbjct: 468 RERFQRDIEFMLGQPFASWKVF---ILRFIAPIILVICLL 504


>UniRef50_A4RP68 Cluster: Transporter; n=2; Sordariomycetes|Rep:
           Transporter - Magnaporthe grisea (Rice blast fungus)
           (Pyricularia grisea)
          Length = 668

 Score =  131 bits (317), Expect = 5e-29
 Identities = 80/253 (31%), Positives = 125/253 (49%), Gaps = 4/253 (1%)

Query: 237 WVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQ-LA 295
           W   ++C  KGV  +G+V+Y T   P +++VIL  R ++LP A  G   YL    S+ LA
Sbjct: 198 WFASWICTFKGVGMTGRVIYVTMALPLIMIVILAVRSLSLPNASDGFRLYLGVWRSESLA 257

Query: 296 NAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFS 355
              VW DA  Q+FF++   +G   + +SYN    N   DS I+A+SN A    + L +  
Sbjct: 258 GPTVWQDAFGQMFFSIGVGFGYFTSYASYNSKFANAVQDSFIIALSNSAIEIVSALAVMG 317

Query: 356 VIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFAL 415
           ++GFL  +   +  R+    +G  F  YP  +  +P +  +S LFF+ L+ LGL   FAL
Sbjct: 318 IVGFLGLDFETT-GRLGTFSSG--FFYYPRALVEMPGANFFSALFFLTLVCLGLTCVFAL 374

Query: 416 METVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLI 475
            E + T I D     R  +  V   V +  YL  L++ T  G   L  +D +  + ++  
Sbjct: 375 YEVLVTMICDSDWGKRVPRWAVSTTVIIASYLITLLYCTEVGFALLDAVDGFVNDLALFF 434

Query: 476 IAIGECILIAWIY 488
               EC+    +Y
Sbjct: 435 TVWCECMFATTLY 447



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 43/133 (32%), Positives = 63/133 (47%), Gaps = 3/133 (2%)

Query: 16  APLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIA 75
           AP +++ E  R N+  R  F            N+ RFP + YNN G  F IP+   L   
Sbjct: 24  APDAKKDEDGRDNFNSRSQFVLCAMGGAVGLGNLLRFPSVVYNNYGLQFFIPYLFALFCI 83

Query: 76  GLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMT 135
           G+P++ +E+  GQ    G V  +N      +G+G+ MV     V  YY  I+A+ + Y  
Sbjct: 84  GIPILCLEICLGQAYRGGCVTAWNNNNHRAKGVGFSMVFNGYSVSGYYVAILAYAMSYFR 143

Query: 136 VSFSSIFYQLPWQ 148
            SF +    LPWQ
Sbjct: 144 RSFEN---PLPWQ 153


>UniRef50_Q0G8L9 Cluster: High-affinity octopamine transporter
           protein; n=2; Pterygota|Rep: High-affinity octopamine
           transporter protein - Anax junius (common green darner)
          Length = 234

 Score =  129 bits (312), Expect = 2e-28
 Identities = 55/112 (49%), Positives = 77/112 (68%), Gaps = 3/112 (2%)

Query: 51  RFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGY 110
           RFPYLCY NGGGAFLIP+T+MLV   LPL +MEL  GQ+   GP++V+ + CPLF+G+G+
Sbjct: 1   RFPYLCYRNGGGAFLIPYTLMLVFGALPLFYMELILGQFNRQGPISVW-RICPLFKGVGF 59

Query: 111 GMVIVSSIVMLYYNLIIAWTIFYMTVSFSSI--FYQLPWQNCKAEWSTKHCY 160
             V+V+  V  YYN+II W ++++  S S+      LPW +C   W+T  C+
Sbjct: 60  CAVLVAFYVSFYYNVIIGWALYFLVASASAAPSSADLPWLHCNNSWNTDACW 111



 Score = 41.1 bits (92), Expect = 0.087
 Identities = 21/71 (29%), Positives = 38/71 (53%), Gaps = 2/71 (2%)

Query: 184 SYSVSHNITALAKTALRRPPAEEYFTNQVLGL--SSGIEETGEIRLGMAMCLLAAWVIVF 241
           +++ SH+     +      PA EYF   VL +  S G+ + G  +  + +C+   + +++
Sbjct: 164 THAHSHHAPQAPQARPANSPASEYFHRAVLEMQGSGGLHDLGVPKWQLVLCVFLVYTMLY 223

Query: 242 LCLCKGVQSSG 252
           L L KGV+SSG
Sbjct: 224 LSLFKGVKSSG 234


>UniRef50_Q6F6P5 Cluster: Transporter; n=2; Acinetobacter|Rep:
           Transporter - Acinetobacter sp. (strain ADP1)
          Length = 492

 Score =  128 bits (309), Expect = 4e-28
 Identities = 87/289 (30%), Positives = 148/289 (51%), Gaps = 14/289 (4%)

Query: 205 EEYFTNQVLGLS--SGIEETGEIRLGMAMCLLAAWVIVFLCLC----KGVQSSGKVVYFT 258
           E +F N  L  S  SG++ T    L     +L  W +  + L     KGV+ S K+  F 
Sbjct: 126 EAFFFNTYLQTSKASGLDLTFVSHLFWP--ILGIWALTLIILYGGVKKGVELSNKI--FM 181

Query: 259 ALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGL 318
            L  +V+  IL  + + LPGA+ G+  + TP++S + + +VW  A    FF+LS  +G +
Sbjct: 182 PLL-FVLFTILVIQSLRLPGAVQGLNAFFTPNWSAMMDYKVWLAAYGHTFFSLSVGFGIM 240

Query: 319 ITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGL 378
           +T +SY K   N     LIV  +N +T   AG+ IF+ +GF+AH     V  VV  G GL
Sbjct: 241 VTYASYLKPKTNLTGSGLIVGFANASTEILAGIGIFAALGFMAHAAGTEVKDVVSGGIGL 300

Query: 379 AFIVYPEVVTRLPI-SPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWV 437
           AFI +P++++ L   + ++ +LFF  L   G+ S  +++E    A+ D+    R+K   V
Sbjct: 301 AFIAFPKIISSLGAGADVFGLLFFSSLFVAGISSMVSILEVPIAAMQDKLKWGRKKA--V 358

Query: 438 VFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAW 486
             I      +   +F++ + +  + ++D +  N  ++  A+   I +AW
Sbjct: 359 TIIGGGSAVVSIFLFSSVNAIKLVDIIDHFINNIGIIGGALLSIITVAW 407



 Score = 94.3 bits (224), Expect = 9e-18
 Identities = 43/121 (35%), Positives = 61/121 (50%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           R NW+ R  F            N+WRFPY+ Y NGGGAFLIP+ + L+ AGLPL+F++ +
Sbjct: 5   RENWSSRSGFIIAAVGSAVGLGNIWRFPYVAYENGGGAFLIPYLLALITAGLPLLFLDYA 64

Query: 86  FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQL 145
            G      P   Y K       LG+  V V  ++ LYY  ++ W   Y+  S   ++   
Sbjct: 65  VGHKGNASPPKAYRKLFKGGETLGWWQVCVCIVIGLYYASVLTWAGSYIYFSVGQMWGSN 124

Query: 146 P 146
           P
Sbjct: 125 P 125


>UniRef50_Q5ARW4 Cluster: Transporter; n=7; Pezizomycotina|Rep:
           Transporter - Emericella nidulans (Aspergillus nidulans)
          Length = 799

 Score =  128 bits (308), Expect = 6e-28
 Identities = 73/253 (28%), Positives = 129/253 (50%), Gaps = 6/253 (2%)

Query: 237 WVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGI-LFYLTPDFSQLA 295
           W ++++ + +GV  +G+VVY+T   P V  +I   R ++L  A  G+ L + T    QLA
Sbjct: 196 WFLIWVSIFRGVGLTGRVVYWTMGLPIVTTIIFVGRSLSLENASEGVKLLWATWRGGQLA 255

Query: 296 NAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFS 355
           +  VW  A  Q+FF+    +G   + +SYN   +N  +D+L++  SN+    FA   +F 
Sbjct: 256 SGTVWQTAVGQVFFSTGIGFGYFTSYASYNAKHSNAVMDALLICGSNVLFENFAAFAVFG 315

Query: 356 VIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFAL 415
           V+G+L H      D V      + F+  PE V  +P S  W+IL F  L+ LG  S F +
Sbjct: 316 VVGYL-HRW--PEDGVRLGAFVVGFLTLPEAVLHMPGSNFWAILLFFTLVVLGFSSAFVM 372

Query: 416 METVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLI 475
           ++ V T ++D     +  +  +V ++ +  +L  L + T  G Y L  +D++  N  ++ 
Sbjct: 373 LDAVATLVVD--SGLKVSRPIIVTVLTLISFLMCLPYCTEFGFYLLDGIDRWINNICLIF 430

Query: 476 IAIGECILIAWIY 488
           +   E +  + +Y
Sbjct: 431 VVWSEVVSASTVY 443



 Score = 78.2 bits (184), Expect = 6e-13
 Identities = 41/133 (30%), Positives = 64/133 (48%), Gaps = 3/133 (2%)

Query: 16  APLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIA 75
           AP  ++ E  R  W  R  F            N+ R+P + YNN G  + IP+ + +   
Sbjct: 15  APPPKQSEDGRDQWPSRAAFLLAAMGGCAGQGNLIRYPSVVYNNYGLQWFIPYFLAIFFV 74

Query: 76  GLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMT 135
            +P + +E+S GQ    G V  +N      +G+G G ++VS IV  Y+ + +AW + Y  
Sbjct: 75  AIPALILEISIGQAYRGGTVIAFNNINRRLKGVGIGPILVSFIVTQYFTVNLAWIMNYFR 134

Query: 136 VSFSSIFYQLPWQ 148
            SF S    LPW+
Sbjct: 135 NSFRS---PLPWE 144


>UniRef50_UPI0000D66570 Cluster: PREDICTED: similar to orphan
           neurotransmitter transporter NTT5; n=6; Murinae|Rep:
           PREDICTED: similar to orphan neurotransmitter
           transporter NTT5 - Mus musculus
          Length = 690

 Score =  126 bits (303), Expect = 2e-27
 Identities = 87/343 (25%), Positives = 160/343 (46%), Gaps = 38/343 (11%)

Query: 19  SEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLP 78
           S E  P R  W  + ++             V RF     + G  +F I + +ML+  G+P
Sbjct: 66  SSEGYPPRQLWASKVEYMLAIMSYLLMPSGVLRFASGWVHKGSCSFFIAYILMLLGIGIP 125

Query: 79  LMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSF 138
           L+F+E++ GQ A      ++    P F G+GY MV+V  I   Y N+  +W +FYM+  F
Sbjct: 126 LLFLEMAVGQRAQQSSADMWKNLSPWFGGVGYSMVMVCFITNTYLNVFNSWILFYMSHIF 185

Query: 139 SSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTA 198
              ++ +PW  C  +   ++  +++   ECE    T Y    + ++   S  I       
Sbjct: 186 ---YFVVPWDQCPLQ---RNSSNFD--PECE--QATSYTYFWYRKTLKASDRI------- 228

Query: 199 LRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFT 258
                 +  F+   LG+S          L ++ CL+ A+++       G++S GKV++  
Sbjct: 229 --EDGGQPSFS---LGMS----------LFLSFCLICAFLV------NGIKSIGKVLFVL 267

Query: 259 ALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGL 318
            L PY ++V    R +++ GA  G+   L    + +++  +W  A +Q+ F +   +G +
Sbjct: 268 LLVPYSIIVCFLIRTLSMDGAEYGLKHLLILKVASISDLTIWCHAGIQVLFDIGLGFGPI 327

Query: 319 ITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLA 361
           ++L+S+    NNC  D+ ++A+  I T       + S++GF A
Sbjct: 328 VSLASHVPDFNNCMADAFLMALFKIITLLMTTPFLLSILGFWA 370



 Score = 93.1 bits (221), Expect = 2e-17
 Identities = 55/163 (33%), Positives = 90/163 (55%), Gaps = 5/163 (3%)

Query: 380 FIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVF 439
           F+++ EV++ LP S  W +LFF++LLTLGL S    M      + D FP  R++   ++ 
Sbjct: 450 FLIFTEVISLLPGSGFWIVLFFLLLLTLGLCSNLMFMLGNVLTLQDTFPFCRRQPRLLIV 509

Query: 440 IVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQR 499
            V++  +L GLIF   SG+Y+  L+ +      V+II I E + +AW YGA++F  D+  
Sbjct: 510 CVSMAMFLCGLIFIQPSGIYYFSLLSECWVAVPVIIIIICENLAVAWAYGADRFLADMVA 569

Query: 500 MIGRQSKLWVYLWSAMWRIITPAALVFIL--VFNWIEYKPASY 540
           ++GR        W  +W  I+P  ++ +L  VF ++   P  Y
Sbjct: 570 LLGRPIFSGCG-W--LWCYISPMVVLGLLTSVFVYLVKGPLVY 609


>UniRef50_O18300 Cluster: Transporter; n=1; Caenorhabditis
           elegans|Rep: Transporter - Caenorhabditis elegans
          Length = 669

 Score =  125 bits (302), Expect = 3e-27
 Identities = 105/482 (21%), Positives = 207/482 (42%), Gaps = 39/482 (8%)

Query: 61  GGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVM 120
           GGAF++ + ++L++ G P++++EL  GQ+    P     +  P+ +G G+ M +VS++ +
Sbjct: 49  GGAFILAYGLILIMLGYPVLYLELIIGQFHRCSPWIFIRRCAPILQGFGF-MALVSAVTI 107

Query: 121 LY-YNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQ 179
           LY Y   +A    ++          +PW  C   W+T       E      QN      +
Sbjct: 108 LYPYQYSVARAFKFLLSLARYRSQDMPWSTCGNWWNT-------ETGHIVFQN------K 154

Query: 180 CFNQSYSVSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVI 239
           C N+        T +   A+     + Y  N +  +            G+A  +   W+ 
Sbjct: 155 CVNE--------TKIKMEAVESAEIQ-YLRNVIHRIGVSHMSFTNFNYGIAYSIFIIWLT 205

Query: 240 VFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQV 299
           +     +    +  ++Y   +F +++   L  R + L GAI G+   L  ++++L  +++
Sbjct: 206 ISFVQNRVNTRTTPLIYIPTVFAFLICHFLLVRSLHLDGAIEGVQEMLRIEWAELLYSKI 265

Query: 300 WGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIG- 358
           W DA   +  +LS   GG   ++S+     N +  + +  + +   S      ++S++G 
Sbjct: 266 WIDALNLVVQSLSIGIGGHTVMASFAPPEKNTFRVATLAVILDTGLSIIISATVYSILGY 325

Query: 359 --FLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPI-SPLWSILFFVMLLTLGLDSQFAL 415
             F+    +V    V+  G  L    +P ++ ++   S LW  L++  L+ +G  S   +
Sbjct: 326 TRFILGRKSVYDLTVLPNGLLLTHSTFPVLLRQVAANSWLWVFLYYSTLVVVGWKSCALI 385

Query: 416 METVTTAILDRFPNFRQKKGW----VVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANW 471
           M+T+T  I D F N + K  +     +F+  V    G  +   +  +Y   + D      
Sbjct: 386 MKTITVTIADIF-NIKMKTYFFDCLCIFVSMVIATSGLFLCFESGPLYLTMIQDIQTVAT 444

Query: 472 SVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSK-LW--VYLWSAMWRIITPAALVFIL 528
            + I A  E  ++  +YG +   GDI  ++G+ S   W   Y W  +W+     A  F +
Sbjct: 445 GIFITA--ELFIVLELYGLDTIYGDIHELMGQPSNDQWSRAYTW-PIWKWRWTTAPAFSI 501

Query: 529 VF 530
           +F
Sbjct: 502 IF 503


>UniRef50_Q4TJ95 Cluster: Transporter; n=1; Tetraodon
           nigroviridis|Rep: Transporter - Tetraodon nigroviridis
           (Green puffer)
          Length = 310

 Score =  124 bits (300), Expect = 5e-27
 Identities = 52/141 (36%), Positives = 76/141 (53%), Gaps = 4/141 (2%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           ER  W  + ++            NVWRFP+LC+ NGGG FL+P+    ++ GLPL  +E 
Sbjct: 1   ERDQWAKKREYILASAGNIVGLGNVWRFPFLCFKNGGGVFLLPYCFFTLLCGLPLFLLET 60

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
             GQY   G V  + K CPL +G+GY  +++  I    Y++++AW +FY+  SFS     
Sbjct: 61  VVGQYTQEGAVTCWTKICPLAQGIGYYTMVI-QIYFRVYSIVLAWAVFYLIYSFSG---T 116

Query: 145 LPWQNCKAEWSTKHCYSYEEA 165
           LPW +C   W+T  C     A
Sbjct: 117 LPWASCSNPWNTDRCVDLSTA 137


>UniRef50_Q4SIS0 Cluster: Transporter; n=2; Tetraodontidae|Rep:
           Transporter - Tetraodon nigroviridis (Green puffer)
          Length = 1250

 Score =  124 bits (300), Expect = 5e-27
 Identities = 58/107 (54%), Positives = 76/107 (71%)

Query: 255 VYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPA 314
           VY TA FPY+VL I   RG+TL GA  G+ +  TP ++ L N QVW DAA QIFF+LS A
Sbjct: 839 VYVTATFPYLVLTIFLVRGLTLDGATVGLTYLFTPKWNTLLNPQVWLDAATQIFFSLSVA 898

Query: 315 WGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLA 361
           +GGLI+ +SYN+  NNC  D+LIV + N ATS +A + +FS++GF A
Sbjct: 899 FGGLISFASYNEEKNNCERDALIVGIINSATSLYASISVFSILGFKA 945



 Score =  117 bits (281), Expect = 1e-24
 Identities = 67/177 (37%), Positives = 99/177 (55%), Gaps = 11/177 (6%)

Query: 375  GAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAI--LDRFPNFRQ 432
            G GLAFI + E V  +P S +W+ILFF+ML TLGL S F  ME +TT +  L+  P +  
Sbjct: 1009 GTGLAFIAFTEAVIEMPASQVWAILFFIMLFTLGLSSMFGNMEGITTPLKDLNVLPKWMP 1068

Query: 433  KKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEK 492
             +     I+ +  +   LIFT  SG YW+++ + Y  +  +L+IA  E I +++IYG  K
Sbjct: 1069 NE-VTSGILCLVSFSVALIFTQGSGNYWVEVFNGYVGSVPLLLIAFFEIIAVSYIYGIRK 1127

Query: 493  FCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKP-ASYGHYVYPMW 548
            F  D+  M G +  ++   W A W +I+P  L+ + VF  I Y    +  H VYP W
Sbjct: 1128 FSEDLDYMNGSRPNIF---WKACWLVISP--LMLLTVF--IAYVALQAQNHPVYPTW 1177



 Score =  116 bits (278), Expect = 3e-24
 Identities = 53/125 (42%), Positives = 69/125 (55%), Gaps = 3/125 (2%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           R  W  R  +            N+WRFPYLC  +GGGAFLIP+ + LV  GLPL+++EL+
Sbjct: 671 RPKWDNRVQYLLSCIGFAVGLGNIWRFPYLCQIHGGGAFLIPYLIALVFEGLPLLYLELA 730

Query: 86  FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQL 145
            GQ    G + V+    PL  G+G   +IVS  V L+YN IIAW ++Y   SF      L
Sbjct: 731 IGQRMRKGSIGVWRTISPLLGGVGMASMIVSFCVCLFYNTIIAWVLWYFFHSFQD---PL 787

Query: 146 PWQNC 150
           PW  C
Sbjct: 788 PWSQC 792



 Score = 92.3 bits (219), Expect = 4e-17
 Identities = 44/121 (36%), Positives = 74/121 (61%), Gaps = 3/121 (2%)

Query: 374 QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAI--LDRFPNFR 431
           +G GLAFIV+ E +T++P SP+WS+LFFVMLL LG+ + F  +E V   +  L+ FP   
Sbjct: 259 EGTGLAFIVFTEAITKMPGSPIWSVLFFVMLLCLGISTLFGNIEGVVVPLKDLNIFPKTW 318

Query: 432 QKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAE 491
             +  +     +  ++  ++F  NSG+YW+ L D +A +  +L I + E I + ++YG +
Sbjct: 319 PHE-VLTGTTCLVAFIITILFAQNSGLYWVTLFDNFAGSIPLLTIGLCEMIAVVYVYGID 377

Query: 492 K 492
           +
Sbjct: 378 R 378



 Score = 78.2 bits (184), Expect = 6e-13
 Identities = 33/91 (36%), Positives = 48/91 (52%)

Query: 18  LSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGL 77
           + +E    R  W  +  +            NVWRFPYLC ++GGGAFLIP+ ++LV+ G 
Sbjct: 23  MEKEDAGNRPKWDNKIQYILTCVGFCIGLGNVWRFPYLCQSHGGGAFLIPYLILLVLEGT 82

Query: 78  PLMFMELSFGQYAALGPVAVYNKFCPLFRGL 108
           PL+ +E + GQ    G V V+    P   G+
Sbjct: 83  PLLLLEFAIGQRLRRGSVGVWRSISPYLAGI 113



 Score = 77.0 bits (181), Expect = 1e-12
 Identities = 35/72 (48%), Positives = 47/72 (65%)

Query: 292 SQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGL 351
           ++LAN   W DA  Q+F+A   AWGGLI+ SSYN   NNC  D++I++V    TS +A  
Sbjct: 125 NELANPTTWLDAGAQVFYAFGLAWGGLISFSSYNSVHNNCVQDAIILSVVTGFTSVYAAT 184

Query: 352 VIFSVIGFLAHE 363
           V +S+IGF A E
Sbjct: 185 VTYSIIGFRATE 196



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 33/71 (46%), Positives = 45/71 (63%), Gaps = 3/71 (4%)

Query: 374 QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK 433
           +G GLAFIV+ E +T++P SP+WS+LFFVMLL LG+ + F  +E V   + D   N   +
Sbjct: 570 EGTGLAFIVFTEAITKMPGSPIWSVLFFVMLLCLGISTLFGNIEGVVVPLKDL--NILSQ 627

Query: 434 KGWVVFIVAVF 444
           K W    V VF
Sbjct: 628 K-WPQEAVTVF 637


>UniRef50_A4VB21 Cluster: Transporter; n=1; Platynereis
           dumerilii|Rep: Transporter - Platynereis dumerilii
           (Dumeril's clam worm)
          Length = 124

 Score =  124 bits (298), Expect = 1e-26
 Identities = 53/103 (51%), Positives = 77/103 (74%), Gaps = 4/103 (3%)

Query: 57  YNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVS 116
           Y NGG +FLIP+ +ML+ AGLPL FME++ GQ+ +LGP++V+ +  P F GLG+ MVI+S
Sbjct: 3   YANGGASFLIPYVIMLLFAGLPLFFMEMALGQFTSLGPISVW-RVAPFFSGLGWAMVIIS 61

Query: 117 SIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHC 159
            +V +YYN+IIA+T++Y+  SF+S   +LPW +CK EW    C
Sbjct: 62  FLVCIYYNMIIAYTLYYIFASFTS---RLPWSDCKEEWLEFGC 101


>UniRef50_UPI0000EBDBFC Cluster: PREDICTED: similar to orphan
           neurotransmitter transporter NTT5; n=2; Bos taurus|Rep:
           PREDICTED: similar to orphan neurotransmitter
           transporter NTT5 - Bos taurus
          Length = 615

 Score =  122 bits (294), Expect = 3e-26
 Identities = 98/359 (27%), Positives = 172/359 (47%), Gaps = 48/359 (13%)

Query: 12  EKSKAPLSEEIEP--ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFT 69
           EK + P  E+ E    R  W+ + ++            ++W F YL  ++GGG FLI + 
Sbjct: 59  EKVQVPEKEKSEVLITRPFWSNKAEYLLAQMGYTMRPASLWSFCYLWLHSGGGIFLIIYI 118

Query: 70  VMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAW 129
            +L + G+PL+F+E++ GQ    G + V+    P   G+GY   +V  I  L+ N++ AW
Sbjct: 119 FLLFLIGIPLLFLEMAAGQRMRQGNIGVWKVISPWIGGVGYTSFMVCFINGLFLNVVTAW 178

Query: 130 TIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYL--RQCFNQSYSV 187
            +FY++ SF    Y +PW+ C      ++   ++   EC     T Y   R     S S+
Sbjct: 179 ILFYLSQSFQ---YPVPWEKCPL---LENASGFD--PECARTTPTLYFWYRMTLKASDSI 230

Query: 188 SHNITALAKTALRRPPAEEYFTNQVLG--LSSGIEETGEIRLGMAMCLLAAWVIVFLCLC 245
             +   +    L   P   + +  +LG  + +G++ TG++     MC+L           
Sbjct: 231 EDDGPPVFSLCL---PL--FLSVCLLGVFMLNGLKWTGKV-----MCVL----------- 269

Query: 246 KGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAV 305
             V SSG +     +  +VV  I+      L GA+ G+ +      S + N  VW  A  
Sbjct: 270 --VSSSGLI-----MLCFVVRSIM------LEGAVFGLHYMTIVKISAIYNVNVWRGAGN 316

Query: 306 QIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHEL 364
           Q+  +L   +G +I+++S+ + S++C  D++IVA++N+ +       IFSV+GF A +L
Sbjct: 317 QVLCSLGLGFGSIISIASHIQSSSSCLNDAVIVALANLISMMLVTPFIFSVLGFWATQL 375



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 36/133 (27%), Positives = 67/133 (50%), Gaps = 3/133 (2%)

Query: 397 SILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNS 456
           S LFF+MLL L + +   +M+++ T++ D F + ++       +V +  +L GL FT  S
Sbjct: 449 SFLFFLMLLNLEMSTMIGIMDSIITSLQDIFISVQKYTKLFTVVVLMIMFLCGLFFTRPS 508

Query: 457 GMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMW 516
           G Y+++L+  Y     ++I+ I E + + W   A  F  D+  + G      +  W  +W
Sbjct: 509 GSYYIRLLTDYWTILPIIIVIIFENLAVKWAREASSFFADMANLWG-HPMYSIIRW--LW 565

Query: 517 RIITPAALVFILV 529
             + P  L+ + V
Sbjct: 566 SYLIPVVLLALSV 578


>UniRef50_Q8IGR3 Cluster: Transporter; n=3; Drosophila
           melanogaster|Rep: Transporter - Drosophila melanogaster
           (Fruit fly)
          Length = 641

 Score =  120 bits (290), Expect = 9e-26
 Identities = 112/485 (23%), Positives = 205/485 (42%), Gaps = 42/485 (8%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGA-FLIPFTVMLVIAGLPLMFMEL 84
           RG W    DF                       +GG   F+I + + ++   LP+  ++ 
Sbjct: 84  RGRWAKSADFYFASCTHAFSSLIFSELSTFGILHGGWLLFIIAYLMGMLFYSLPIFLIQA 143

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
             GQ+++ G ++ + +  P+F+G+GY +++++   + YY++     + Y   + +SI   
Sbjct: 144 FLGQFSSSGTISAF-RVAPIFKGIGYAILLLNLGTLTYYSIAAVVPLIY---TVNSIHPV 199

Query: 145 LPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPA 204
           +PW +C   W+T+ C  +E  D                  Y V  + T            
Sbjct: 200 IPWMSCNNSWNTQECSLHENYDV---------------DDYRVDPHSTV----------- 233

Query: 205 EEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264
            E+F + +   + G   +  I   M + +L+ W++V   L K V   GKV+  + +  + 
Sbjct: 234 -EFFRSMIASTAKG-STSMSISWSMLIGVLSIWLVVLALLLKPVAFIGKVLRCSCVLMFG 291

Query: 265 VLVILFFRGVTLPGAIT--GILFYLTPDFSQLANAQVWGDAAVQIFF-ALSPAWGGLITL 321
             V +F   + +   IT   + +Y  P      +       A+ +   AL P WG +ITL
Sbjct: 292 FFVAVFLY-LLIHEQITFDTLHYYWMPQLDSFDSILATARTALLMAGGALGPGWGSIITL 350

Query: 322 SSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAF- 380
           SSYN F  +    S+ V +++I T    GL+  +V      +    +   VD+   + F 
Sbjct: 351 SSYNNFRRDAERLSIWVCLTHI-TIGLMGLLCCNVAHDHFEDHVGMMPLHVDEKHHMQFL 409

Query: 381 -IVYPEVVTRLPISP-LWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVV 438
            + +  +  R   +P LW+ LFF M+    L +    M +V TA+ D F   R ++  V+
Sbjct: 410 YLCFSYLFGRFTTTPNLWAFLFFGMIFLSELCALIIQMMSVITALFDEFETLRSRRILVI 469

Query: 439 FIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQ 498
             +        + F T  G   L  +   A    +LI  I   ++  W+YG  +F  D+Q
Sbjct: 470 SSLVFCLTASSVYFCTQLGFSQLTQLPNLAVFTHLLISGI-LVLMTTWVYGRVRFQCDLQ 528

Query: 499 RMIGR 503
            M+G+
Sbjct: 529 FMLGK 533


>UniRef50_Q2VFP2 Cluster: GABA-a receptor 3-like protein; n=1;
           Mytilus galloprovincialis|Rep: GABA-a receptor 3-like
           protein - Mytilus galloprovincialis (Mediterranean
           mussel)
          Length = 127

 Score =  119 bits (286), Expect = 3e-25
 Identities = 54/97 (55%), Positives = 71/97 (73%)

Query: 196 KTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVV 255
           +T  +  P+EE++ N+ L ++ GIE  G IR  + +CL  AWV+VFLCLCKGV+SSG+VV
Sbjct: 30  ETVKQITPSEEFWENRALKMTDGIENFGGIRWELLICLTIAWVLVFLCLCKGVKSSGRVV 89

Query: 256 YFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFS 292
           Y TA FPY+VL+IL  RGVTLPGA  G+ FYL P  +
Sbjct: 90  YVTATFPYLVLLILLIRGVTLPGASEGLKFYLIPQMT 126


>UniRef50_UPI000059FF44 Cluster: PREDICTED: similar to Orphan
           sodium- and chloride-dependent neurotransmitter
           transporter NTT5 (Solute carrier family 6 member 16);
           n=8; Laurasiatheria|Rep: PREDICTED: similar to Orphan
           sodium- and chloride-dependent neurotransmitter
           transporter NTT5 (Solute carrier family 6 member 16) -
           Canis familiaris
          Length = 798

 Score =  117 bits (282), Expect = 8e-25
 Identities = 49/131 (37%), Positives = 78/131 (59%), Gaps = 3/131 (2%)

Query: 20  EEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPL 79
           +E   ER +W  + ++             +WRFPYLC++NGGG+FLI + +ML + G+PL
Sbjct: 79  KETPIERPSWANKIEYLLAQVGFSVGLSTIWRFPYLCFHNGGGSFLIIYILMLFLVGVPL 138

Query: 80  MFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFS 139
           +F+E++ GQ    G + V+    P   G+GY   ++  IV LYY++++AW++FY+  SF 
Sbjct: 139 LFLEMAAGQRMRQGSIGVWKVISPWIGGVGYTSFMMCCIVSLYYSVLMAWSLFYLVQSFQ 198

Query: 140 SIFYQLPWQNC 150
              Y LPW  C
Sbjct: 199 ---YPLPWALC 206



 Score =  101 bits (242), Expect = 6e-20
 Identities = 50/157 (31%), Positives = 84/157 (53%)

Query: 207 YFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVL 266
           ++   VL  +  IE  G     +++ L A W+I+ + + KG + +GK++Y + + PY ++
Sbjct: 228 FWYRHVLKATDEIEMGGLPVTHLSISLFATWLIICISMIKGPKFTGKMLYVSVILPYFII 287

Query: 267 VILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNK 326
             L  R + L GA  G+   L      L + +VW     QIF ++ P +G    +SSY  
Sbjct: 288 FCLLIRSLMLEGAYFGLKNLLAAKVRSLYSVEVWRRTGNQIFLSMGPGFGSFTAISSYIP 347

Query: 327 FSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHE 363
            SNNC +D+ +VA  N+  S  A L +F+++G LA E
Sbjct: 348 QSNNCVMDAFVVAFLNLTASLTATLFVFAIMGHLATE 384



 Score =  100 bits (239), Expect = 1e-19
 Identities = 61/200 (30%), Positives = 106/200 (53%), Gaps = 8/200 (4%)

Query: 334 DSLIVAVSNIATSFFAGL---VIFSVIGFLAH-ELNVSVDRVVDQGAGLAFIVYPEVVTR 389
           DSL    S+I + +F  L   +   V+ +L++  L   +  V++ G G+A + + ++++ 
Sbjct: 414 DSLYHDPSSIYSQWFKSLPEQIKDVVLPYLSNCNLTYQLKEVME-GPGVAIVAFTDIISV 472

Query: 390 LPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGG 449
              S  WSI+ F+ML  LGL +   +M  +   + D F + R+    +   + V  +LG 
Sbjct: 473 FSGSTFWSIIIFMMLANLGLSTMIGIMHGIIIPLQDTFSSLRKNIILLTVGICVSLFLGS 532

Query: 450 LIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWV 509
           LIF   SG Y++ L+D Y A+  + +  I E I IAWIYGA +F  D+  M+GR     +
Sbjct: 533 LIFVRPSGSYYVNLLDDYWASLPLFLTVILENIAIAWIYGARRFLADLIIMLGRPISP-I 591

Query: 510 YLWSAMWRIITPAALVFILV 529
           Y W  +W  ++P  L+ + +
Sbjct: 592 YRW--LWCFLSPFVLLVLFL 609


>UniRef50_Q4SNN3 Cluster: Transporter; n=1; Tetraodon
           nigroviridis|Rep: Transporter - Tetraodon nigroviridis
           (Green puffer)
          Length = 559

 Score =  117 bits (281), Expect = 1e-24
 Identities = 69/218 (31%), Positives = 102/218 (46%), Gaps = 34/218 (15%)

Query: 17  PLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAG 76
           P  ++    RG W  + ++            NVWRFPYLCY NGG            + G
Sbjct: 8   PKKQKAGGARGQWASKTEYILVVAGQVVGLGNVWRFPYLCYKNGG------------VCG 55

Query: 77  LPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTV 136
           +PL  +E S GQ+   G +  + K CPL +G+GYG ++   +    + +I AW +FY+  
Sbjct: 56  IPLFLLETSLGQFTQEGFITCWRKICPLAQGIGYGQLLF-KVYGFVFVIIQAWALFYLVF 114

Query: 137 SFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAK 196
           SF S   +LPW  C   W+T +C S +  D               + S +   N T L  
Sbjct: 115 SFRS---ELPWVTCNNSWNTANCRSLQAVD---------------SSSVNYITNQTVLPN 156

Query: 197 TALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLL 234
           T+     A E+   +VLGLS GIEE G + +G  + L+
Sbjct: 157 TS---TAATEFLERRVLGLSRGIEELGGVSVGSGVLLV 191



 Score =  102 bits (244), Expect = 3e-20
 Identities = 46/96 (47%), Positives = 64/96 (66%)

Query: 316 GGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQG 375
           G L+ L SY+  +NNCY D   + + N +TSF AG V+FSV+GF+A E  V+V+ VV  G
Sbjct: 187 GVLLVLGSYSPSNNNCYRDCFWLCLLNSSTSFVAGFVVFSVLGFMAEEQGVAVNTVVRSG 246

Query: 376 AGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDS 411
            GLAFI YP+    LP+   WS+ FF+ML+ L +D+
Sbjct: 247 PGLAFIAYPQATALLPLPQFWSVCFFLMLILLAVDT 282



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 20/113 (17%)

Query: 144 QLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPP 203
           Q+PW  C   W+T  C  Y++                       S N+T    T +    
Sbjct: 349 QIPWATCNNPWNTDKCRVYQDLSPA-------------------SSNLTGNETTQMNATT 389

Query: 204 AE-EYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVV 255
           A  E++  ++L +S GIEE G +   + +CLLA+WV  +  + KGV+SSGK V
Sbjct: 390 AATEFWERRMLRMSGGIEEVGSVSWELTLCLLASWVFCYFSIWKGVRSSGKFV 442



 Score = 44.8 bits (101), Expect = 0.007
 Identities = 26/98 (26%), Positives = 44/98 (44%), Gaps = 4/98 (4%)

Query: 396 WSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK---KGWVVFIVAVFGYLGGLIF 452
           W   +F +   +    +F  +E+  T + D FP +  K   +   V +V    +L  L+ 
Sbjct: 424 WVFCYFSIWKGVRSSGKFVDVESFITTVSDMFPKWFHKPMRQEIFVLVVCASAFLVQLLL 483

Query: 453 TTNSGMYWLQLMDKYAANWSV-LIIAIGECILIAWIYG 489
            T  G+Y  Q  D YA+        AI EC+ + W++G
Sbjct: 484 VTQGGIYIFQFFDYYASTRICGYFFAICECLALGWMFG 521


>UniRef50_Q17EZ3 Cluster: Sodium/shloride dependent amino acid
           transporter; n=1; Aedes aegypti|Rep: Sodium/shloride
           dependent amino acid transporter - Aedes aegypti
           (Yellowfever mosquito)
          Length = 331

 Score =  111 bits (267), Expect = 5e-23
 Identities = 51/131 (38%), Positives = 75/131 (57%), Gaps = 4/131 (3%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           ER  W    +F            NVWRFP++   NGGGAF+IP+ ++L++ G P+ +ME+
Sbjct: 72  ERDQWGKGIEFLMSCIAMSVGLGNVWRFPFIALQNGGGAFVIPYIIVLLLVGKPVYYMEM 131

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ 144
             GQ+++ G V VY+   P  RG+GYG V+  +IV  YY  ++A T+ Y+  SF  I   
Sbjct: 132 IIGQFSSRGSVKVYD-CAPAMRGVGYGQVLSIAIVSTYYASLMATTLKYLFESFQKI--- 187

Query: 145 LPWQNCKAEWS 155
           LPW  C   W+
Sbjct: 188 LPWATCDDSWA 198



 Score = 43.2 bits (97), Expect = 0.022
 Identities = 20/57 (35%), Positives = 32/57 (56%), Gaps = 3/57 (5%)

Query: 101 FCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTK 157
           F    +G+G+G +   + ++ YY+ ++A    YM  SF S    LPW NC+ EW T+
Sbjct: 247 FIKHIKGVGFGQLFSVTSLITYYSSLMALIGRYMYESFKS---PLPWANCRPEWGTE 300


>UniRef50_A3CV46 Cluster: Transporter; n=1; Methanoculleus
           marisnigri JR1|Rep: Transporter - Methanoculleus
           marisnigri (strain ATCC 35101 / DSM 1498 / JR1)
          Length = 431

 Score =  109 bits (263), Expect = 2e-22
 Identities = 86/277 (31%), Positives = 136/277 (49%), Gaps = 21/277 (7%)

Query: 260 LFPYVVLVILFFRGVTL--PGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGG 317
           L P +++++LF   V+L  PGA  GI FYL+PDFS+L +  VW  A  Q FF+LS   G 
Sbjct: 161 LIPVLLVILLFLVAVSLTEPGAAEGIGFYLSPDFSRLTDPAVWIAAFGQAFFSLSVGMGI 220

Query: 318 LITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAG 377
           L+T  SY K     + ++ I+A +++  +  AGLVIF ++          +D     G  
Sbjct: 221 LLTFGSYLK-REALFRNAAIIAAADMLIAVLAGLVIFPLV------FTAGLDPAA--GVN 271

Query: 378 LAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWV 437
           LAFI  P   T +    +   LFF+ML    L S  +++E  T A++D +   R++   +
Sbjct: 272 LAFITLPTAFTEIRYGMVLGTLFFLMLFAAALTSAVSMLEVPTAALMDSYGYPRKRATLL 331

Query: 438 VF-IVAVFGYLGGLIFTTNS----GMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEK 492
           VF  V +FG    L +T  +    GM +L L D       +++  +   I+  W     +
Sbjct: 332 VFAAVMLFGLPSALSYTALNLEALGMPFLDLADYVFGTIGLIVAGLIISIVGGWFMTRTR 391

Query: 493 FCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILV 529
              +I    G Q K+++    A+ R   PA L+  LV
Sbjct: 392 IYAEIGG-CGWQQKVYM----ALIRYGVPAVLLITLV 423



 Score = 87.4 bits (207), Expect = 1e-15
 Identities = 38/109 (34%), Positives = 58/109 (53%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           ER  W+    F            N+WRFPY+   NGGGAFLIPF + +++ GLPLM +EL
Sbjct: 2   EREEWSSTLGFILASIGSAVGIGNIWRFPYVVGANGGGAFLIPFLIAVLLFGLPLMVLEL 61

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFY 133
           + G+      ++ +      F   G  +V V S+++ YY +I +W + Y
Sbjct: 62  AIGRSTGTSVISAFRSIRQRFAAAGLVIVAVVSLILGYYLVITSWVLAY 110


>UniRef50_Q9GZN6 Cluster: Orphan sodium- and chloride-dependent
           neurotransmitter transporter NTT5; n=9; Eutheria|Rep:
           Orphan sodium- and chloride-dependent neurotransmitter
           transporter NTT5 - Homo sapiens (Human)
          Length = 736

 Score =  102 bits (244), Expect = 3e-20
 Identities = 56/210 (26%), Positives = 114/210 (54%), Gaps = 6/210 (2%)

Query: 335 SLIVAVSNIATSFFAGLV--IFSVIGFLAHELNVSVDRV-VDQGAGLAFIVYPEVVTRLP 391
           +L+   ++I  ++ +GL   I S++     E N+    +   +G   AF+ + E ++ LP
Sbjct: 433 NLLYNPTSIYNAWLSGLPQHIKSMVLREVTECNIETQFLKASEGPKFAFLSFVEAMSFLP 492

Query: 392 ISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLI 451
            S  WS +FF+MLL +GL S   +M+ + T + D F  FR+    ++  V +  ++ GL 
Sbjct: 493 PSVFWSFIFFLMLLAMGLSSAIGIMQGIITPLQDTFSFFRKHTKLLIVGVFLLMFVCGLF 552

Query: 452 FTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQ-SKLWVY 510
           FT  SG Y+++L+  Y   + ++++ + E + ++W YGA +F  D+  ++G   S ++ +
Sbjct: 553 FTRPSGSYFIRLLSDYWIVFPIIVVVVFETMAVSWAYGARRFLADLTILLGHPISPIFGW 612

Query: 511 LWSAMWRIITPAALVFILVFNWIEYKPASY 540
           LW  +  ++    ++F+ +   +  KP +Y
Sbjct: 613 LWPHLCPVV--LLIIFVTMMVHLCMKPITY 640



 Score = 91.5 bits (217), Expect = 6e-17
 Identities = 45/140 (32%), Positives = 75/140 (53%), Gaps = 7/140 (5%)

Query: 15  KAPLSEEIEPE----RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTV 70
           K  ++E+ E E    R  W+ + ++             +WRF YL  N+GG +F   +  
Sbjct: 88  KVQMTEKKESEVLLARPFWSSKTEYILAQVGFSMKPSCLWRFAYLWLNSGGCSFAAIYIF 147

Query: 71  MLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWT 130
           ML + G+PL+F+E++ GQ    G + V+    P   G+GY   +V  I+ LY+N++ +W 
Sbjct: 148 MLFLVGVPLLFLEMAAGQSMRQGGMGVWKIIAPWIGGVGYSSFMVCFILGLYFNVVNSWI 207

Query: 131 IFYMTVSFSSIFYQLPWQNC 150
           IFYM+ SF    + +PW+ C
Sbjct: 208 IFYMSQSFQ---FPVPWEKC 224



 Score = 84.2 bits (199), Expect = 9e-15
 Identities = 49/162 (30%), Positives = 76/162 (46%)

Query: 200 RRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTA 259
           R  P+  ++  Q L  S  IE+ G     + +     W +V   +  G++S+GKV+Y   
Sbjct: 239 RTTPSIYFWYQQALKASDRIEDGGSPVYSLVLPFFLCWCLVGAFMINGLKSTGKVIYVLV 298

Query: 260 LFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLI 319
           L P  ++V  F R + L GA  G+   +    S + N  VW  A  Q+        G + 
Sbjct: 299 LLPCFIIVGFFIRTLLLEGAKFGLQQLVVAKISDVYNMSVWSLAGGQVLSNTGIGLGSVA 358

Query: 320 TLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLA 361
           +L+SY   SNNC  D+ +V+V N+ T        F V+GF A
Sbjct: 359 SLASYMPQSNNCLSDAFLVSVINLLTLLVFTSFNFCVLGFWA 400


>UniRef50_UPI000059FF45 Cluster: PREDICTED: similar to solute
           carrier family 6, member 20 isoform 2; n=1; Canis lupus
           familiaris|Rep: PREDICTED: similar to solute carrier
           family 6, member 20 isoform 2 - Canis familiaris
          Length = 686

 Score =  100 bits (240), Expect = 1e-19
 Identities = 39/103 (37%), Positives = 66/103 (64%), Gaps = 3/103 (2%)

Query: 48  NVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRG 107
           ++WRFPYLC+ NGGG F++ +  ML++ G+PL++ME+  G +  +  + V+ +  P   G
Sbjct: 61  SIWRFPYLCHRNGGGNFILMYFFMLLLFGIPLLYMEMIMGHWLRMDNIRVWKQLVPWLGG 120

Query: 108 LGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNC 150
           +GY  ++V  ++ LY ++II W+I Y+  SF +    LPW  C
Sbjct: 121 IGYASILVCILISLYNSIIITWSISYLGNSFDN---SLPWNQC 160



 Score = 51.6 bits (118), Expect = 6e-05
 Identities = 28/99 (28%), Positives = 53/99 (53%), Gaps = 4/99 (4%)

Query: 433 KKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEK 492
           K  +   ++ + G+LG L+FT+++G Y + L D Y    +++II   + + +A IYGA +
Sbjct: 446 KPAFATVLICLGGFLGSLVFTSHAGSYIMSLFDDYLIPLTLVIIVTFQNVALACIYGARR 505

Query: 493 FCGDIQRMIGRQSKLWVYLWSAMWRIIT-PAALVFILVF 530
              +I   +GR   LW + +  +W  +T P  L    ++
Sbjct: 506 VREEIFSDLGR--LLWSF-FIVLWCYVTLPGLLALTTIY 541



 Score = 49.2 bits (112), Expect = 3e-04
 Identities = 18/59 (30%), Positives = 37/59 (62%)

Query: 374 QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQ 432
           +G GLAF+ + +V++  P +  W+ILFF+ L+ +GL +   ++E + + + +    FR+
Sbjct: 340 EGPGLAFVAFSQVISLFPGASFWAILFFLALVIMGLSTSIQILEGIVSPLQNSISTFRR 398


>UniRef50_O67854 Cluster: Transporter; n=1; Aquifex aeolicus|Rep:
           Transporter - Aquifex aeolicus
          Length = 513

 Score =  100 bits (240), Expect = 1e-19
 Identities = 88/308 (28%), Positives = 135/308 (43%), Gaps = 13/308 (4%)

Query: 244 LCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPG-AITGILFYLTPDFSQLANAQVWGD 302
           + KG++   K+   T     V LVI  F   T  G A  G+ F  TPDF +L +  VW  
Sbjct: 187 ISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIA 246

Query: 303 AAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAH 362
           A  QIFF LS  +G +IT +SY +   +  +  L  A  N       G  I S+   +A 
Sbjct: 247 AVGQIFFTLSLGFGAIITYASYVRKDQDIVLSGLTAATLNEKAEVILGGSI-SIPAAVAF 305

Query: 363 ELNVSVDRVVDQGA-GLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTT 421
               +   +   GA  L FI  P + ++         L+F +L   GL S  A+M+ +  
Sbjct: 306 FGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSSIAIMQPMIA 365

Query: 422 AILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGEC 481
            + D       +K  V++  A+  +   L+   N     L  MD +A    V+   + E 
Sbjct: 366 FLEDELK--LSRKHAVLWTAAIVFFSAHLVMFLNKS---LDEMDFWAGTIGVVFFGLTEL 420

Query: 482 ILIAWIYGAEKFCGDIQR-MIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASY 540
           I+  WI+GA+K   +I R  I +  +++ Y    + R ITPA L  +LV    EY P   
Sbjct: 421 IIFFWIFGADKAWEEINRGGIIKVPRIYYY----VMRYITPAFLAVLLVVWAREYIPKIM 476

Query: 541 GHYVYPMW 548
               + +W
Sbjct: 477 EETHWTVW 484



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 36/116 (31%), Positives = 56/116 (48%), Gaps = 6/116 (5%)

Query: 22  IEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMF 81
           +E +R +W  R               N  RFP     NGGGAF+IP+ +  ++ G+PLM+
Sbjct: 1   MEVKREHWATRLGLILAMAGNAVGLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMW 60

Query: 82  MELSFGQY-AALGPVAVYNKFCPLFRG-----LGYGMVIVSSIVMLYYNLIIAWTI 131
           +E + G+Y  A G       F  L+R      LG   + +  +V +YY  I +WT+
Sbjct: 61  IEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVAIYYVYIESWTL 116


>UniRef50_UPI0000F2D4C7 Cluster: PREDICTED: hypothetical protein;
           n=1; Monodelphis domestica|Rep: PREDICTED: hypothetical
           protein - Monodelphis domestica
          Length = 718

 Score = 99.5 bits (237), Expect = 2e-19
 Identities = 86/314 (27%), Positives = 138/314 (43%), Gaps = 62/314 (19%)

Query: 50  WRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLG 109
           WRFPYLC+ NGGG+F++ +  +L   G PL+FME++ GQ         + +  P   GL 
Sbjct: 110 WRFPYLCHENGGGSFIVSYVFLLFAMGFPLIFMEMALGQNLHFSG---WKQIHPRMWGLN 166

Query: 110 YGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECE 169
               ++S +++LY          Y  V   SIFY      C   WS           +C 
Sbjct: 167 LATCLISFMLLLY----------YNAVIAWSIFYLGNSFLCPLPWS-----------QCP 205

Query: 170 A-QNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLG 228
              NGT  + +C                  +R  P+  ++  + L ++  IEE G +   
Sbjct: 206 VGANGTSEVLEC------------------VRTRPSIYFWFRETLMVTGSIEEGGGLVFS 247

Query: 229 MAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPG-AITGILFYL 287
           + +CLL  WV +     +G+Q+ GKV                 RG  L   +I G+L ++
Sbjct: 248 LTVCLLVVWVSILFIWLQGLQAKGKV-----------------RGGALGAXSIFGMLHFI 290

Query: 288 TPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSF 347
               S + + +VW  A  Q+F +     G +I L S     NNC  D+ ++  +++A+  
Sbjct: 291 QIKKSLITSTKVWRQAGAQMFISTGLGIGNIIFLYSCAT-KNNCAQDAFMLTFTHMASCL 349

Query: 348 FAGLVIFSVIGFLA 361
               VIFS++GF A
Sbjct: 350 LTTQVIFSMLGFQA 363



 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 49/164 (29%), Positives = 89/164 (54%)

Query: 374 QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK 433
           QG GL F+ + E VT  P S  W++LFF++L++ GL+   + ++   T + D FP+    
Sbjct: 435 QGPGLVFVAFTEAVTSFPGSSFWAVLFFLLLISQGLNISVSQLQGTLTLLQDIFPSLSNF 494

Query: 434 KGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKF 493
              +       G+L  L+FT  SG+Y+L+L D+  A   ++I+   E + +AWIYGA++F
Sbjct: 495 SLTISVTYCCLGFLCSLLFTQRSGLYFLKLFDEILATLPLIIMIFFETVGVAWIYGAKRF 554

Query: 494 CGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKP 537
             ++  M+  + KL        + ++    L+ I + ++I  +P
Sbjct: 555 LDEVWAMLEFKIKLMHEYVLRYYTLLGVMILIIISLLDFIMEQP 598


>UniRef50_UPI0000E49EF2 Cluster: PREDICTED: similar to solute
           carrier family 6 (neurotransmitter transporter,
           noradrenalin), member 2; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to solute carrier
           family 6 (neurotransmitter transporter, noradrenalin),
           member 2 - Strongylocentrotus purpuratus
          Length = 275

 Score = 99.5 bits (237), Expect = 2e-19
 Identities = 46/100 (46%), Positives = 63/100 (63%), Gaps = 2/100 (2%)

Query: 8   KGDEEKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIP 67
           + + EK+    SEE E ER  W  + DF            NVWRFPYL Y NGGGAFLIP
Sbjct: 157 RDEYEKNNDDDSEE-EEERETWGTKVDFLLSVIGFSVDLANVWRFPYLVYRNGGGAFLIP 215

Query: 68  FTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRG 107
           + + L+I G+P+++MEL+ GQY   G ++V+ K CP+F+G
Sbjct: 216 YVLFLLIGGIPMLYMELALGQYNRGGAISVW-KICPIFQG 254


>UniRef50_Q7NXF6 Cluster: Transporter; n=4; Bacteria|Rep:
           Transporter - Chromobacterium violaceum
          Length = 440

 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 67/214 (31%), Positives = 114/214 (53%), Gaps = 15/214 (7%)

Query: 246 KGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAV 305
           KG+++  K +   ALF   ++++L  RG+TLPGA+ G+ +++ PDFS+++ A +  DA  
Sbjct: 163 KGIEALSKFL-MPALF--ALMLVLIARGLTLPGALEGVSYFVAPDFSKVS-ASMLVDALG 218

Query: 306 QIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELN 365
             FF+LS   G +IT  SY    +     +L V +  +AT F AGL++   +   A   +
Sbjct: 219 LAFFSLSLGLGIMITYGSYVGRESKLLGSALWVILLTVATCFLAGLMVLPAV--FAFGFD 276

Query: 366 VSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILD 425
            S       G GL FI  P V   LP+  L++++FF +LL   L S  +L+E VT+  +D
Sbjct: 277 PSA------GPGLTFITMPAVFAHLPLGQLFAVMFFCLLLLAALTSSVSLLEVVTSFAID 330

Query: 426 RFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMY 459
                R  +     ++A   +L G+  + + G++
Sbjct: 331 ---ELRLSRRTAAILMAAGTFLLGIPASLSLGVW 361



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 36/113 (31%), Positives = 56/113 (49%), Gaps = 1/113 (0%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           R  W  R  F             +W+FPY+   NGGGAFL  +  + +  GL LM  E++
Sbjct: 3   RSQWGSRLGFILAAAGSAIGLGAIWKFPYVAATNGGGAFLFIYLGICLTLGLVLMLAEMA 62

Query: 86  FGQYAALGPVAVYNKFCPLFRGL-GYGMVIVSSIVMLYYNLIIAWTIFYMTVS 137
            G+  + G V  + K    F  L GY  V+V  +++ +Y+++  WTI Y+  S
Sbjct: 63  LGRATSAGAVGAFRKLAGGFWPLIGYMGVLVCFLILSFYSVVGGWTIAYIVKS 115


>UniRef50_UPI0000E4A5E3 Cluster: PREDICTED: similar to creatine
           transporter, partial; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to creatine
           transporter, partial - Strongylocentrotus purpuratus
          Length = 141

 Score = 97.9 bits (233), Expect = 7e-19
 Identities = 41/81 (50%), Positives = 52/81 (64%), Gaps = 1/81 (1%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           R  W+GR DF            NVWRFPYLCY NGGGAFLIP+ +  V+ G+PL F+E +
Sbjct: 62  RERWSGRLDFLLSCVGFAVGLGNVWRFPYLCYKNGGGAFLIPYFICAVLGGIPLFFIEAA 121

Query: 86  FGQYAALGPVAVYNKFCPLFR 106
            GQY +LG +  + K CPLF+
Sbjct: 122 LGQYTSLGGIKAW-KICPLFQ 141


>UniRef50_A6NZ68 Cluster: Transporter; n=1; Bacteroides capillosus
           ATCC 29799|Rep: Transporter - Bacteroides capillosus
           ATCC 29799
          Length = 478

 Score = 97.9 bits (233), Expect = 7e-19
 Identities = 88/331 (26%), Positives = 149/331 (45%), Gaps = 23/331 (6%)

Query: 209 TNQVL-GLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSS-GKVVYFTALFPYVVL 266
           T  VL G S+   +T  +  G       A  +  L L  GV +   K+  F     +V+ 
Sbjct: 164 TGSVLSGDSAAFFDTLAVDFGSVPWHFIAVALTVLVLVLGVSAGIEKISKFMMPAFFVLF 223

Query: 267 VILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNK 326
           +I+  R   LPGA+ G L+ L PD+S L N + W  A  Q FF+LS    G++   SY K
Sbjct: 224 LIIAVRVAFLPGAVDGYLYLLKPDWSYLLNPETWIMAMGQAFFSLSINGAGMLIYGSYMK 283

Query: 327 FSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEV 386
            S +    S++ A+ +   +  AG  I   +     E           G  L F+  P+V
Sbjct: 284 KSEDIIHHSVVTALLDTMAALLAGFAIIPAVFAFGIE--------PASGPSLMFVTLPKV 335

Query: 387 VTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGY 446
              +P   L+++LFFV +   G+ S   ++E    A+       R     +V +V VFG 
Sbjct: 336 FQLMPGGQLFALLFFVSVFFAGITSLMNMLEACGAALESNLKLPRWLSTTIVGVV-VFGV 394

Query: 447 LGGLIFTTNSGM-YWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQ- 504
              +   + SGM  WL L+  Y A +  ++ A    + I W+ G +    ++  M+GR  
Sbjct: 395 --SVFLESLSGMGSWLDLITIYVAPFGAVLGA----VFIYWVLGLDPIKKEL--MLGRDK 446

Query: 505 --SKLWVYLWSAMWRIITPAALVFILVFNWI 533
              K + ++   ++ I++ A ++F +++  I
Sbjct: 447 PIGKAFDFIAKYVYVILSAAVVIFGIIYGGI 477



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 28/127 (22%), Positives = 53/127 (41%), Gaps = 7/127 (5%)

Query: 17  PLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAG 76
           P+S       G +     F            N+W FPY     GGGAFLIP+ + + +  
Sbjct: 37  PMSHHNSAHSGKFRSSAGFILAAVGSAVGMGNIWLFPYRVGQYGGGAFLIPYFIFVALFS 96

Query: 77  LPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVI-VSSI-----VMLYYNLIIAWT 130
              +  E + G+    G +  ++ +    RG   G +I +  +     + + Y++++ W 
Sbjct: 97  YAGLSGEFALGRLTGTGTIGSFD-YALKIRGKRGGKIIGIMPLLGVLGIAIGYSVVVGWV 155

Query: 131 IFYMTVS 137
           + Y+  S
Sbjct: 156 LRYIAGS 162


>UniRef50_Q2S448 Cluster: Sodium-and chloride-dependent transporter;
           n=3; Bacteria|Rep: Sodium-and chloride-dependent
           transporter - Salinibacter ruber (strain DSM 13855)
          Length = 507

 Score = 97.5 bits (232), Expect = 1e-18
 Identities = 93/348 (26%), Positives = 159/348 (45%), Gaps = 34/348 (9%)

Query: 207 YFTNQVLGLSSGIEETGE---IRLGM-AMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFP 262
           Y    VL  + G E       + +G+ A  LL   ++V   + KG++   K++    LF 
Sbjct: 169 YAVKDVLAPTMGFEAFAASPWLNVGLVAFFLLLTLLVVVGGVEKGIERWAKIL-LPVLFV 227

Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322
            ++LVI+  R VTL GA  G+ FYL PDFS++    V   A  Q FF LS   G +IT  
Sbjct: 228 LILLVIV--RAVTLDGAAEGLRFYLVPDFSEITFDLVIA-ALGQAFFTLSLGMGAMITYG 284

Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIV 382
           SY     +  +    V + N   +  AG +IF  +        +  D     G  L F+V
Sbjct: 285 SYLPKREDIAMSGGYVVLFNTMIALMAGFMIFPAL------FAMGADPAT--GPALVFVV 336

Query: 383 YPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKK----GWVV 438
            PEV  ++P+  +   LFF++L    L S  +L+E V +  +D     R+K     G + 
Sbjct: 337 LPEVFAQMPLGGIVEFLFFLLLSIAALTSSISLLEVVVSYFVDEKNWSRRKSVLIIGVIT 396

Query: 439 FIVAV-----FGYLGG---LIFTTNSGMYW-----LQLMDKYAANWSVLIIAIGECILIA 485
           F++A+     FG +G    L +    G  +     L ++D    +  + + A    + I 
Sbjct: 397 FLMALPSALSFGAVGAFSDLSYLFGEGGLFGQNNVLGVLDYLIGSAGLAVGAFFLSVFIG 456

Query: 486 WIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWI 533
           W++GA++   ++++     +  ++ +W    R I P  +VF +V  ++
Sbjct: 457 WVWGADRAADELRQGSSTLADGFLGVWIFGMRYIIP-VVVFGIVMGYL 503



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 39/149 (26%), Positives = 67/149 (44%), Gaps = 12/149 (8%)

Query: 11  EEKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTV 70
           E   + P+S     +R  W+ +  F            N+WRFPYL    GGGAF++ + +
Sbjct: 45  EPTRRLPMSTT-STDREQWSSQIGFVLAAAGSAIGLGNIWRFPYLAGEGGGGAFVLIYLL 103

Query: 71  MLVIAGLPLMFMELSFGQYAALGPVAVYNKFC---PLFRGLGYGMVIVSSIVMLYYNLII 127
            ++  G+P +F ELS G+ +   PV            +  +G   V+   +++ YY+++ 
Sbjct: 104 CILFIGMPYLFGELSLGRNSQKNPVGAIKSITGGGSAWIVVGGFCVLAGFVILSYYSVVA 163

Query: 128 AWTIFYM-------TVSFSSIFYQLPWQN 149
            W + Y        T+ F + F   PW N
Sbjct: 164 GWAVGYAVKDVLAPTMGFEA-FAASPWLN 191


>UniRef50_A7T6E6 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 244

 Score = 94.7 bits (225), Expect = 7e-18
 Identities = 53/171 (30%), Positives = 91/171 (53%), Gaps = 11/171 (6%)

Query: 107 GLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEAD 166
           GLGYG +++  +  +YY +I+AW +FY+  SF S    +PW++C   W+T  C +     
Sbjct: 3   GLGYGTLVMQFLSNIYYIVILAWVLFYLFDSFRS---HVPWESCGNWWNTPFCSTRPRNS 59

Query: 167 -------ECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAEEYFTNQVLGLSSGI 219
                  +C     ++Y     +Q+ + S     +  +     P+EEY+TN+VL ++  +
Sbjct: 60  RLLWVELKCVPHTPSFYFMTA-SQTVNCSAFALPVNCSQTFTSPSEEYWTNRVLQITDSL 118

Query: 220 EETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILF 270
           E+ GEIR  +   L+ +WV+V+ C+ K V+ +GKV  + A   Y  L I F
Sbjct: 119 EDMGEIRWELVGTLILSWVLVYFCIFKSVRLTGKVWVYAATQIYWSLGIGF 169



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 26/48 (54%), Positives = 35/48 (72%)

Query: 377 GLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAIL 424
           GL FI YPE +++LP S  W+ILFF ML+TLGLD+   L+ +VT  I+
Sbjct: 194 GLVFIAYPEAISQLPGSVFWAILFFTMLVTLGLDTMVRLIPSVTGTIV 241



 Score = 40.7 bits (91), Expect = 0.12
 Identities = 19/51 (37%), Positives = 29/51 (56%)

Query: 280 ITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNN 330
           ++ +L Y     S     +VW  AA QI+++L   +GG+IT  S+N F NN
Sbjct: 134 LSWVLVYFCIFKSVRLTGKVWVYAATQIYWSLGIGFGGIITFGSFNSFKNN 184


>UniRef50_Q8U3T4 Cluster: Putative transporter; n=1; Pyrococcus
           furiosus|Rep: Putative transporter - Pyrococcus furiosus
          Length = 430

 Score = 94.3 bits (224), Expect = 9e-18
 Identities = 59/201 (29%), Positives = 105/201 (52%), Gaps = 12/201 (5%)

Query: 224 EIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGI 283
           E  L + + +     IV + + +G++ + K++    LF  V+L++L  R VTLP A  G+
Sbjct: 139 EALLWLFVVIALTIAIVAMGVQRGIERANKIM-MPLLF--VLLIVLAVRSVTLPNAYEGL 195

Query: 284 LFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNI 343
            FYL PD S++A+ + W  A  Q+FF+LS     ++   SY +  ++  + ++  A  + 
Sbjct: 196 KFYLLPDLSKIASGKTWMIALSQMFFSLSVLGNTMVVYGSYLREEDDIPLSAIATAFGDT 255

Query: 344 ATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVM 403
           A +  AG ++F  +     E           G GL F+  P V  ++P   ++S LFF++
Sbjct: 256 AVAVTAGFIVFPAVFSFGLEPTA--------GPGLVFVTLPMVFQKMPGGMIFSALFFLL 307

Query: 404 LLTLGLDSQFALMET-VTTAI 423
           L+  GL S  +++E  V +AI
Sbjct: 308 LIFAGLSSTVSMLEVYVDSAI 328



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 33/114 (28%), Positives = 52/114 (45%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           R  W  R  F            N+W FP      GG AFLIP+ V+L   G+  + +E +
Sbjct: 6   RETWGSRVGFVAAAIGSAVGLGNIWMFPMRAGLYGGAAFLIPYLVLLFAVGVVALTVEWT 65

Query: 86  FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFS 139
            G+    GP+  + K  P  + LG  + +   ++  +Y+L++ W I Y   S S
Sbjct: 66  LGRATKGGPIEAFEKTLPGGKYLGILVNVTILMIFAFYSLVLGWVIRYFIASLS 119


>UniRef50_Q800X8 Cluster: GABA transporter GAT-3; n=9;
           Euteleostomi|Rep: GABA transporter GAT-3 - Chelydra
           serpentina serpentina (common snapping turtle)
          Length = 107

 Score = 93.1 bits (221), Expect = 2e-17
 Identities = 41/74 (55%), Positives = 54/74 (72%)

Query: 203 PAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFP 262
           P  E++  +VL +S GIE  G +R  +A+CLLAAW I + C+ KG +S+GKVVY TA FP
Sbjct: 34  PVMEFWERRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFP 93

Query: 263 YVVLVILFFRGVTL 276
           YV+L+IL  RGVTL
Sbjct: 94  YVMLLILLVRGVTL 107


>UniRef50_Q9X7H2 Cluster: Transporter; n=5; Neisseria|Rep:
           Transporter - Neisseria meningitidis
          Length = 445

 Score = 93.1 bits (221), Expect = 2e-17
 Identities = 80/303 (26%), Positives = 134/303 (44%), Gaps = 18/303 (5%)

Query: 235 AAWVIVFLCLCKGVQSSGKVVYFTALFP--YVVLVILFFRGVTLPGAITGILFYLTPDFS 292
           A ++++ + + KG  S G       L P  +++ + L  R +TLPGA+ G+ F L P++S
Sbjct: 147 ALFMLITVWVVKGGISDGIEKANRYLMPGLFILFIALAIRSLTLPGAMEGVSFLLKPNWS 206

Query: 293 QLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLV 352
               A     A  Q FFALS     +IT +SY     + +     +   N+  S  AGLV
Sbjct: 207 YF-KADTMITALGQAFFALSIGVSAMITYASYLGKDQDMFRSGHTIMWMNLLVSLLAGLV 265

Query: 353 IFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQ 412
           IF  +     E +        QG GL FIV P V  ++P   +   +F ++++   L S 
Sbjct: 266 IFPAVFAFGFEPS--------QGPGLIFIVLPAVFMKMPFGTVLFAVFMLLVVFATLTSA 317

Query: 413 FALMETVTTAILDRFPNFRQKKGWV----VFIVAVFGYLGGLIFTTNS--GMYWLQLMDK 466
           F+++ETV  + + +    R+K  W+    +FIV +   L   I+      G     L D 
Sbjct: 318 FSMLETVIASTIRQDERKRKKHTWLIGTAIFIVGIPSALSFGIWGEFKVFGKTIFDLWDY 377

Query: 467 YAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVF 526
             +   + + A+G  +  AWI   +    D         +  + LW    R + P A++ 
Sbjct: 378 VISAVIMPVGALGVAVFTAWIQDKQSVLKDAGAG-STVPRAVLLLWLNRKRYLAPIAIII 436

Query: 527 ILV 529
           + V
Sbjct: 437 VFV 439



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 28/114 (24%), Positives = 51/114 (44%), Gaps = 2/114 (1%)

Query: 28  NWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFG 87
           +W+ +  F             +W+FPY    NGG  F + F +  V+  LP+   E   G
Sbjct: 6   SWSSKIGFVLAAAGSAIGLGAIWKFPYTAGTNGGAVFFLLFLIFTVLVALPVQLAEFYIG 65

Query: 88  QYAALGPVAVYNKFCPLFRGLGYGMVIVSS--IVMLYYNLIIAWTIFYMTVSFS 139
           +      V  +    P  + L  G + VS+  I++ +Y+++  W + Y+  SF+
Sbjct: 66  RTGGQNAVDSFRALRPSTQWLWVGRMGVSACFILLSFYSVVGGWVLNYVVHSFT 119


>UniRef50_Q6AQ17 Cluster: Probable sodium-dependent transporter;
           n=1; Desulfotalea psychrophila|Rep: Probable
           sodium-dependent transporter - Desulfotalea psychrophila
          Length = 470

 Score = 92.7 bits (220), Expect = 3e-17
 Identities = 83/309 (26%), Positives = 139/309 (44%), Gaps = 25/309 (8%)

Query: 231 MCLLAAWVIVFLCLCKGVQSS---GKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYL 287
           +CL    ++V + +  G+Q        V    LF  VV++ L+   +T PGA+ G  F L
Sbjct: 167 LCLTYFTILVVIAVASGIQKGIERWNKVMMPTLFGIVVVLALY--SLTTPGAVAGWKFML 224

Query: 288 TPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSF 347
            PDFS+L    V  +A    FF LS A G L+T +SY       +  ++ +A  +   + 
Sbjct: 225 YPDFSKLTMGGVL-EAIGHSFFTLSIAMGILVTYASYMDKKEKIFPVAIRIAFLDTVVAI 283

Query: 348 FAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTL 407
            AGL IF ++     E           G GL F   P+   ++P   +   LFFV++   
Sbjct: 284 GAGLAIFPIVFSFGMEPGA--------GPGLIFKTLPKAFAQMPFGNVLGTLFFVLMAFA 335

Query: 408 GLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVF--GYLGGLIFTTNS------GMY 459
            L S  +L+E +T   +D    + +KK  ++  +AV+  G    L ++T S      GM 
Sbjct: 336 ALSSAISLLEVLTAFAIDE-KKYDRKKATIIMAIAVYIAGIPSALSYSTFSDITIWGGMP 394

Query: 460 WLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRII 519
            L  +D  A+N+ + I  +   +   +I        +I     +  K++  +W    R +
Sbjct: 395 ILDGLDHMASNYMLPIGGLLIAVYAGFIVDKRILQAEITEDGAKYVKVF-RVWYFTIRYV 453

Query: 520 TPAALVFIL 528
           TP  LVF++
Sbjct: 454 TP-VLVFVV 461



 Score = 81.4 bits (192), Expect = 7e-14
 Identities = 34/120 (28%), Positives = 65/120 (54%), Gaps = 3/120 (2%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           R +W+G   F            N+W+FPY+   NGGGAF++ + V +++ G+PL+  E +
Sbjct: 24  RNHWSGSMGFILAAVGSAVGLGNIWKFPYITGMNGGGAFVLVYLVAILLCGMPLLMAEFA 83

Query: 86  FGQYAALGPVAVYNKFCPLFRG---LGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIF 142
            G+++    V  +    P  +G   +G+  +  + I++ YY +I  WT+FY+  + ++ F
Sbjct: 84  IGRHSQKDVVGSFRDLMPKSKGWQIVGWLNLSAAFIILSYYGVIAGWTLFYLFEAVTNNF 143


>UniRef50_Q2S4H8 Cluster: Sodium-and chloride-dependent transporter;
           n=2; Bacteria|Rep: Sodium-and chloride-dependent
           transporter - Salinibacter ruber (strain DSM 13855)
          Length = 485

 Score = 91.9 bits (218), Expect = 5e-17
 Identities = 40/125 (32%), Positives = 67/125 (53%), Gaps = 2/125 (1%)

Query: 20  EEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPL 79
           +++E  R  W  RF F            N+WRFPY+   NGGGAFL+ + V+L++  +P 
Sbjct: 4   QDVELSRAQWGSRFGFLMAMLGAMVGAGNIWRFPYVTGENGGGAFLLAYFVLLLVLAIPG 63

Query: 80  MFMELSFGQYAALGPVAVYNKFCPL--FRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVS 137
           +  E++FG+YA  G +  + +        GLG  +++V+  +M YY  ++ WT++Y   S
Sbjct: 64  LIAEVAFGRYAGKGVIGAFREVASSRGMVGLGVVVLVVNVALMSYYAPVVGWTLYYAVHS 123

Query: 138 FSSIF 142
               F
Sbjct: 124 LLFTF 128



 Score = 75.8 bits (178), Expect = 3e-12
 Identities = 74/310 (23%), Positives = 137/310 (44%), Gaps = 25/310 (8%)

Query: 231 MCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPD 290
           M L+AA  I++L + +GV+   ++V +      + LV +  R +TLPGA  G+ F    +
Sbjct: 157 MALVAA--ILYLGIRRGVE---RLVIYAVPGLVLALVAIMIRALTLPGAAEGLAFTFGIE 211

Query: 291 FSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYI-DSLIVAVSNIATSFFA 349
           + +L   Q W  A  Q+ F+    WG  +T+ SY    ++  I   +   + N +    A
Sbjct: 212 WGKLGLGQTWITALGQVLFSTGLGWGIALTVGSYLPDYDDIPIGGGVFTVIGNSSIGILA 271

Query: 350 GLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGL 409
              IF ++   A +L+         GA L F+  P+V  ++    LW+ILFF+       
Sbjct: 272 AFAIFPIV--FAFDLDPG------SGASLTFVSLPQVFPQMAGGALWAILFFLGFFLAAF 323

Query: 410 DSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAA 469
            S   + E   T + +     R++   V+ +  V  +L GL    + G+  L  +D    
Sbjct: 324 TSAILITEVSVTTLSEETRLTREQT--VIGVCGVI-WLLGLGSAYSPGV--LNFLDFVFG 378

Query: 470 NWSVLIIAIGECILIAWIYGAEKFCGDIQRM--IGRQSKLWV-YLWSAMWRIITPAALVF 526
           N+ + +  +     I W  G      +  R+  I R + L+V  +W  + + + P  ++ 
Sbjct: 379 NFGLPLSTLAIIGAIGWSMG--HLGPEKLRVLEINRNAGLYVGSIWGPVVQYVIPLVMLL 436

Query: 527 ILV-FNWIEY 535
           I+  + W  +
Sbjct: 437 IVANYAWANF 446


>UniRef50_P45320 Cluster: Uncharacterized sodium-dependent
           transporter HI1690; n=36; Proteobacteria|Rep:
           Uncharacterized sodium-dependent transporter HI1690 -
           Haemophilus influenzae
          Length = 457

 Score = 91.9 bits (218), Expect = 5e-17
 Identities = 78/303 (25%), Positives = 137/303 (45%), Gaps = 23/303 (7%)

Query: 238 VIVFLCLCKGVQSS--GKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLA 295
           ++ ++ L KG+       V Y   L  ++ L+ +  R VTLPGA+ GI FYL PDFS++ 
Sbjct: 167 IVNYIILAKGIIGGIERSVKYLMPLL-FIFLIGMVIRNVTLPGAMEGITFYLKPDFSKI- 224

Query: 296 NAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFS 355
             Q++     Q+FFALS  +G LITLSSY     N    ++I   +N   +  AG +IF 
Sbjct: 225 TPQLFIFVLGQVFFALSLGFGVLITLSSYLNKEENLIHTAVITGFTNTIIAVLAGFMIFP 284

Query: 356 VIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFAL 415
            +     E N         G  L F   P V + L     ++I+FF +LL   L +   +
Sbjct: 285 SLFTFGIEPNA--------GPTLVFQSLPIVFSHLWAGKFFAIIFFGLLLIAALTTSITI 336

Query: 416 METVTTAILDRFPNFRQKKGWV----VFIVAVFGYLGGLIFTTNSGMYWLQLMDKY---A 468
            E + TA+ ++    R K   +    +F++     + G     N  ++   + D Y   +
Sbjct: 337 YEVIITALQEKLRMCRGKAIVLTLSGIFLLGNIPAILGDNLWKNVTIFGKSIFDFYDYAS 396

Query: 469 ANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFIL 528
            N   ++ A+G  I + ++   E      + +   +   ++ +W    + + P  ++ I 
Sbjct: 397 GNILFMLTALGCAIFVGFVLKDEA----KKELSSTKYSTFIKIWFNYVKFVVPLIILVIF 452

Query: 529 VFN 531
           + N
Sbjct: 453 ISN 455



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 30/118 (25%), Positives = 57/118 (48%), Gaps = 8/118 (6%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           +R  W+ R  +              WRFPYL   NGGGA+++ F + +++ G+P++ +E 
Sbjct: 7   QRQTWSSRLTYVMTVAGATVGFGATWRFPYLVGENGGGAYVLLFCIAMIVIGIPMILVEN 66

Query: 85  SFGQYAALGPVAVY-NKFCPLFRG-------LGYGMVIVSSIVMLYYNLIIAWTIFYM 134
             G+   +  +  + +K     +G       LGY  ++ +  +M YY ++  W I Y+
Sbjct: 67  VIGRRLRVNSIDAFGDKILDKGKGISKYWKILGYMGLLGAFGIMAYYMVLGGWVISYI 124


>UniRef50_Q5WAS4 Cluster: SNF family sodium-dependent transporter;
           n=2; Bacillus|Rep: SNF family sodium-dependent
           transporter - Bacillus clausii (strain KSM-K16)
          Length = 443

 Score = 91.5 bits (217), Expect = 6e-17
 Identities = 81/314 (25%), Positives = 146/314 (46%), Gaps = 29/314 (9%)

Query: 227 LGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFY 286
           LG+ + +    V++   +  G++ + K  Y   L  ++ L+I+ FRG++L GA+ G+ F+
Sbjct: 143 LGLVLFVFLNVVVLSFGIKNGIERANK--YLMPLL-FLFLLIIIFRGLSLEGAMEGVRFF 199

Query: 287 LTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATS 346
           L PDFS++  A    +A  Q FF+L+  +  ++T SSY     +    +  VA  N+  S
Sbjct: 200 LQPDFSKI-TAPGLLEALGQSFFSLAVGFSCMVTYSSYLGEKQSLPGSAAYVAAMNVFVS 258

Query: 347 FFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLT 406
             AGL IF ++   A+ +  +       G GL FI  P +  ++P   L+  LF ++   
Sbjct: 259 LLAGLAIFPIV--FAYGIEPA------SGPGLLFIALPAIFAQMPFGALFLSLFLLLFFF 310

Query: 407 LGLDSQFALMETVTTAILD----RFPNFRQKKGWVVFIVAVFGYL-GGLIFTTNSGMYWL 461
             + S  +L+E + +A          N     G VV + A+   L  GL+    SG  W 
Sbjct: 311 ATITSSLSLLEIIISAFTQNKGWNRRNVAMGSGVVVIVAAIPSALSAGLL----SGFAWQ 366

Query: 462 Q--LMDKYAANWSVLIIAIGECILIAWIYG----AEKFCGDIQRMIGRQSKLWVYLWSAM 515
           +  + D      S +++ +G C+LIA   G     +      Q   G   ++  + W  +
Sbjct: 367 EKTVFDLTDLLVSNVMLPVG-CLLIALFVGYKIKRDLLFHQFQLAAGPVGRIAPF-WLFL 424

Query: 516 WRIITPAALVFILV 529
            R + PA ++ + +
Sbjct: 425 MRTLVPATILLVFI 438



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 35/114 (30%), Positives = 53/114 (46%), Gaps = 2/114 (1%)

Query: 29  WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQ 88
           WT +  F             +WRFPYL   NGGGAF + F +  V  GLPL+  E   G+
Sbjct: 5   WTSKIGFILASAGAAIGLGALWRFPYLTGTNGGGAFFLLFILFTVFIGLPLLIAEFVIGR 64

Query: 89  YAALGPVAVYNKF--CPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSS 140
            A    V+ Y K      +  +G   V+   ++M +Y ++  W + Y  +SF +
Sbjct: 65  GAKREAVSAYPKLVNSKAWSWIGRFGVVGCFLLMTFYAVVGGWILLYALLSFGN 118


>UniRef50_Q5DG59 Cluster: Transporter; n=1; Schistosoma
           japonicum|Rep: Transporter - Schistosoma japonicum
           (Blood fluke)
          Length = 282

 Score = 91.1 bits (216), Expect = 8e-17
 Identities = 52/192 (27%), Positives = 93/192 (48%), Gaps = 8/192 (4%)

Query: 342 NIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFF 401
           N + S    + ++S +G+L+    + + ++ D   GL FIVY  V   L  S LW    F
Sbjct: 2   NASISLLNSITLYSFMGYLSQYYAIPIHQIFDGNLGLIFIVYTNVFDTLSASHLWCAFLF 61

Query: 402 VMLLTLGLDSQFALMETVTTAILDRFPNFR--QKKGWVVFIVAVF---GYLGGLIFTTNS 456
            ML+TLGL S     E+  TA+ D    F+   KK + + +V  F    +L  ++     
Sbjct: 62  AMLVTLGLGSSIGATESFLTAVSDDCTIFKLNTKKHFRLGLVTAFLVSSFLISILTVCQG 121

Query: 457 GMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMW 516
           G Y +  +D YA   S++++++G+C  I ++YG      +I  +    +K   ++   + 
Sbjct: 122 GYYLVHYLDHYACGTSLILVSLGQCFAIVYVYGIYNLSENINEI---TNKAIHFITRFIL 178

Query: 517 RIITPAALVFIL 528
           +   P  L+F+L
Sbjct: 179 KFCVPLILIFML 190


>UniRef50_Q8TSA2 Cluster: Sodium/chloride-dependent transporter;
           n=5; cellular organisms|Rep: Sodium/chloride-dependent
           transporter - Methanosarcina acetivorans
          Length = 459

 Score = 91.1 bits (216), Expect = 8e-17
 Identities = 88/327 (26%), Positives = 142/327 (43%), Gaps = 33/327 (10%)

Query: 222 TGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAIT 281
           TGE+   MA+ ++  + +  L L  GV+   K +  + +F  ++L+IL F+ VTLPGA  
Sbjct: 147 TGELIFWMALVVILGFFVCSLGLQAGVERISKFM-MSGMF--LMLLILVFKAVTLPGASA 203

Query: 282 GILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVS 341
           G+ FYL PDFS      V+  A  Q FF LS   G +    SY     +   ++L V   
Sbjct: 204 GLNFYLKPDFSNFNWEGVYA-AMGQAFFTLSLGIGSMAIFGSYIGKERSLTGEALDVMAL 262

Query: 342 NIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFF 401
           +   +  AGLVIF      A    V        G GL F+  P +  ++    LW ILFF
Sbjct: 263 DTLIALLAGLVIFPT----AFAFGVD----AGSGPGLVFVTLPNIFNQMIGGQLWGILFF 314

Query: 402 VMLLTLGLDSQFALMETVTTAILDRFPNFRQK----KGWVVFIVAV-----FGYLGGLIF 452
           + L    + +  A+ E +    +D +   R+K     G  +FI ++     FG L G   
Sbjct: 315 MFLTFAAMTTVIAVFENIMAFTIDEWGWERKKAALRNGIGIFIFSLPCVLGFGPLSGFA- 373

Query: 453 TTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWI-----YGAEKFCGDIQRMIGRQSKL 507
               G   L L D   +N    ++ IG  + + +      +G   F  +     G +   
Sbjct: 374 PLGEGTMVLDLEDFILSN---NLLPIGALVFVLFCTRRPGWGWNSFIEEADTGTGFKFPK 430

Query: 508 WVYLWSAMWRIITPAALVFILVFNWIE 534
           W+       R + P  ++ +L+  W++
Sbjct: 431 WL---KPYVRSVLPLIILVVLIKGWMD 454



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 34/128 (26%), Positives = 59/128 (46%), Gaps = 3/128 (2%)

Query: 18  LSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGL 77
           +S++ + ER  +  R  F            NVWRFP++    GG AF++ +   L++ GL
Sbjct: 1   MSKKKKVEREQFASRIGFLLISAGCAIGLGNVWRFPFITGKYGGAAFVLVYLAFLLLLGL 60

Query: 78  PLMFMELSFGQYAALGPVAVYNKFCPL---FRGLGYGMVIVSSIVMLYYNLIIAWTIFYM 134
           P+M ME + G+   L          P+   +   GY  +I + I+M++Y  +  W + Y 
Sbjct: 61  PIMVMEFAIGRAGHLNIAGSMRALEPVNSKWHVFGYLGIIGNVILMMFYTTVAGWGLAYF 120

Query: 135 TVSFSSIF 142
               +  F
Sbjct: 121 YKELTGAF 128


>UniRef50_Q9KDT3 Cluster: Sodium-dependent transporter; n=2;
           Bacteria|Rep: Sodium-dependent transporter - Bacillus
           halodurans
          Length = 453

 Score = 90.2 bits (214), Expect = 1e-16
 Identities = 84/308 (27%), Positives = 139/308 (45%), Gaps = 24/308 (7%)

Query: 230 AMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPY--VVLVILFFRGVTLPGAITGILFYL 287
           A+ ++A   IV + + KG++ S K+     L P   V+L+ L    +TL GA  G+ F  
Sbjct: 154 ALFMIATIWIVAIGVKKGIERSNKI-----LMPLLGVLLIALAIYSLTLGGAKEGLAFLF 208

Query: 288 TPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSF 347
           +PD+S L +  V+  A  Q FF LS   G LIT  SY   S +  +    V+V+ + T+F
Sbjct: 209 SPDWSALKDPGVYLAAISQAFFTLSLGMGALITYGSY--VSKDSRLPGAAVSVAGLDTAF 266

Query: 348 --FAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLL 405
              AG++IF  +   A  L+ S       G GL F+V P++   + + P+  I FF++L 
Sbjct: 267 AIIAGIMIFPAV--FALGLSPS------GGPGLVFVVLPDIFDSIRLGPIVGIAFFILLG 318

Query: 406 TLGLDSQFALMETVTTAILDRFPNFRQKKGWVV-FIVAVFGYLGGLIFTTNSGMY---WL 461
              L S  +L+E      + +F   R++    +  I+ + G    L F     +     L
Sbjct: 319 AAALSSAVSLLEVPVAYFMRKFDWSRKQAAITLGVIITLLGIPSSLSFGVLGEVTIIPGL 378

Query: 462 QLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITP 521
            + D      S + + +G  I+  +I    K   D          +W  LW    R I P
Sbjct: 379 NIFDSVDFIASSVFLPLGGMIIALFIGWGWK-TSDALAESDLTDSVWGKLWILSLRFIAP 437

Query: 522 AALVFILV 529
            A++ + +
Sbjct: 438 IAILIVFL 445



 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 2/111 (1%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           R  W  R  F            N+WRF Y+   NGG AFL+ +   + + G+P++  E +
Sbjct: 9   REQWASRLGFILAAMGSAVGLGNIWRFSYVTGENGGAAFLLVYLGFIALIGIPIVLAEFT 68

Query: 86  FGQYAALGPVAVYNKFCP--LFRGLGYGMVIVSSIVMLYYNLIIAWTIFYM 134
            G+ A    V  + K  P   ++  G   V    +++ +Y +I  W +FY+
Sbjct: 69  IGRRAQSDAVGSFEKLAPGKPWKVAGLMGVAAGFLILSFYGVIAGWILFYL 119


>UniRef50_A6TKT9 Cluster: Transporter; n=2; Clostridiaceae|Rep:
           Transporter - Alkaliphilus metalliredigens QYMF
          Length = 499

 Score = 89.8 bits (213), Expect = 2e-16
 Identities = 62/263 (23%), Positives = 118/263 (44%), Gaps = 13/263 (4%)

Query: 231 MCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPD 290
           + +L A  I++  +  G++ + K++  T    +V+L+    R +TLPGA+ G+ +  TP+
Sbjct: 151 LSMLIAGFIIYKGVKGGIEKASKIMIPTL---FVLLIAAVIRALTLPGALQGLEYLFTPN 207

Query: 291 FSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAG 350
              L N  +W +A  Q  ++    WG +IT S Y K   +   + +I+   +   +  A 
Sbjct: 208 LHMLKNPTIWLEAFTQAAWSTGAGWGFIITYSVYTKQKEDVAGNCMIMGFGDNIGALIAA 267

Query: 351 LVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLD 410
           + +   I  L+     + + +     G+ FI   ++ T +P     + +FF+ +    L 
Sbjct: 268 MTVLPAIYALSPTPEFAAEALSSGNTGITFIYLAQLFTTMPAGQFLAAIFFLAMAISALS 327

Query: 411 SQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAAN 470
           S   ++E     ++D    F +KK     +VA  G+L G+        Y L  +D     
Sbjct: 328 SLLPMIEVGVRNLMDM--GFDRKKATASIVVA--GFLLGI-----PSAYSLHFLDNQDWV 378

Query: 471 WSVLIIAIGECILIAWI-YGAEK 492
           W V ++  G  +  A   YG E+
Sbjct: 379 WGVGLLVSGLFVAFALAKYGLER 401



 Score = 78.6 bits (185), Expect = 5e-13
 Identities = 34/115 (29%), Positives = 58/115 (50%), Gaps = 1/115 (0%)

Query: 29  WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQ 88
           W  R  F            N+WRFP +   NGGG F+I +T+ L +  +PL+  E+  G+
Sbjct: 8   WGSRIGFIAAAIGMAIGTGNIWRFPRVAAANGGGPFVIAWTIALFVWAIPLLMGEMVMGR 67

Query: 89  YAALGPVAVYNKFC-PLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIF 142
              LG +  +  F    +  +G  + +V   +M YY++++ WT+ Y T++ S  F
Sbjct: 68  KTGLGTIGAFRDFVGKKYTWMGTWIAVVCLGIMFYYSVVMGWTMKYFTLAVSGAF 122


>UniRef50_Q8F511 Cluster: Transporter; n=4; Leptospira|Rep:
           Transporter - Leptospira interrogans
          Length = 511

 Score = 89.4 bits (212), Expect = 3e-16
 Identities = 82/338 (24%), Positives = 145/338 (42%), Gaps = 14/338 (4%)

Query: 204 AEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPY 263
           A  Y+ +      +G   + +I      C +  + +VF  + KG+++  K+     L   
Sbjct: 126 AGNYYLDLTGARHNGDAISSKIFYATITCFILNFALVFRGISKGIETFAKIAVPLMLVSS 185

Query: 264 VVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSS 323
           ++++I   R +TL     G+     PD+S L  ++VW  AA Q+FF LS  +G  +  SS
Sbjct: 186 IIILI---RVLTLDNIDIGLGKMWNPDWSALLKSEVWIAAAGQVFFTLSAGFGIALVFSS 242

Query: 324 YNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGA-GLAFIV 382
           Y K  N+  + S+  A  N       G +I   + FL   L  S++   D G  G+ FI 
Sbjct: 243 YLKRDNDVVLSSISAASLNEFVEVAVGGMITIPVAFLF--LGSSIN---DFGMFGMGFIA 297

Query: 383 YPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVA 442
            P V + +P    +  ++F +L    + S   +++     + + F   R+    ++F+  
Sbjct: 298 LPSVFSLMPGGQWFGAIWFFVLFLAAITSSVTMLQPGIIFLEESFGLKRKTSCLILFLFT 357

Query: 443 VFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIG 502
               L   I   N     L+L D +     + I+A  +  L  W  GA+K   D     G
Sbjct: 358 --ASLSFPILYFNQNFEALELADFWIGTILIFILASIQIFLFGWKIGAKKGLEDGNE--G 413

Query: 503 RQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASY 540
              +L  + W  + + ITP  L+ I +   I+  P  +
Sbjct: 414 SHLELPKFFWFVI-QYITPTFLLVIFIAFLIQNLPGHF 450



 Score = 46.4 bits (105), Expect = 0.002
 Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 5/91 (5%)

Query: 48  NVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAA-LGPVA--VYNKFCPL 104
           N  RFP     NGGGAF++P+ +  ++ G+P+   E   G+     G  A  ++  F   
Sbjct: 10  NFIRFPGQAVANGGGAFMVPYIISFILVGIPVCITEWIMGRMGGRTGHSAPFLFKSFLSG 69

Query: 105 F--RGLGYGMVIVSSIVMLYYNLIIAWTIFY 133
           F  R +G   + +  ++ +YY  I AW + Y
Sbjct: 70  FPLRIVGAIGITIPILIYVYYVFIEAWCLAY 100


>UniRef50_UPI0000D57368 Cluster: PREDICTED: similar to CG8485-PA,
           isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG8485-PA, isoform A - Tribolium castaneum
          Length = 976

 Score = 88.6 bits (210), Expect = 4e-16
 Identities = 66/254 (25%), Positives = 109/254 (42%), Gaps = 36/254 (14%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           R +W  R  +            N + FP   Y  GG  F IP+TV+ +  G PL  ++ S
Sbjct: 76  RLHWRNRITYVIGFMAFTLSLNNAYHFPMNIYRYGGN-FFIPYTVVTIFVGYPLHVLQTS 134

Query: 86  FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQL 145
            GQY+  G + ++ +  P   G+G  MV+   +V LY+N+  A+ + Y    F  +   L
Sbjct: 135 MGQYSQRGVLWMW-ECAPFCCGVGVAMVLACFLVALYHNIFAAYALVYFAHCFHLV---L 190

Query: 146 PWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAE 205
           PW          +C   E+AD             C   S+ +S NI            ++
Sbjct: 191 PWT---------YCSEVEDADA----------HACAPPSWYISQNINL---------SSQ 222

Query: 206 EYFTNQVLGL---SSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFP 262
           EYF N V+     S  +   G I+  + + L  +WV+ ++ + + V+S GK+  F  +  
Sbjct: 223 EYFYNVVVDTNDKSHYLWSLGSIKWWLVLSLAFSWVVCYIAVLRSVRSIGKICIFIIILS 282

Query: 263 YVVLVILFFRGVTL 276
           Y  L+ L    + L
Sbjct: 283 YFTLLTLIIVALQL 296


>UniRef50_A5ZSS6 Cluster: Transporter; n=5; Clostridiales|Rep:
           Transporter - Ruminococcus obeum ATCC 29174
          Length = 465

 Score = 88.6 bits (210), Expect = 4e-16
 Identities = 82/298 (27%), Positives = 136/298 (45%), Gaps = 18/298 (6%)

Query: 239 IVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQ 298
           I++  +  GV+   K +    +F  +V+ +     VT PGA+ G+ ++L P+    +   
Sbjct: 167 IIYAGVRNGVERVSKFMMPVLVFLSIVITVY---SVTRPGALEGVKYFLIPNPKNFSWMT 223

Query: 299 VWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIF-SVI 357
           V   A  Q+F++LS A G L+T  SY K   +    +  V + + A +  AGL+I  +V 
Sbjct: 224 VVA-AMGQMFYSLSIAMGILVTFGSYMKKDVSIESSTTNVEIFDTAIAIMAGLMIIPAVF 282

Query: 358 GFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALME 417
            F   + N      +  G  L FI  P+V   + +     ILFFV++L   L S  AL E
Sbjct: 283 AFSGGDPNT-----LQAGPALMFITIPKVFASMGLGTPIGILFFVLVLCAALTSSIALTE 337

Query: 418 TVTTAILDRFPNFRQKKGWVV-FIVAVFGYL-----GGLIFTTNSGMYWLQLMDKYAANW 471
           +  +   D     RQK   VV  I+ V G L     G L      GM +L   D    + 
Sbjct: 338 SAVSTFQDELKWCRQKSTLVVGAIMIVLGSLSSLGYGPLACVKIIGMQFLDFFDFLTNSV 397

Query: 472 SVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILV 529
            + I AI  C+LI+ + G +K   ++  ++G  +     +++ M + + P     IL+
Sbjct: 398 MMPIAAIATCLLISRVIGLKKIEDEV--VLGEGTFKRKKIFNFMIKYLCPIFAAIILL 453



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 4/123 (3%)

Query: 15  KAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVI 74
           K    E+   ER  ++G+  F            N+WRFPYL    GGG FL+ + ++ + 
Sbjct: 5   KGNFMEQHHHERSTFSGKLGFVLSAAGASVGLGNIWRFPYLAAKYGGGIFLLIYIILAMT 64

Query: 75  AGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYG---MVIVSSIVMLYYNLIIAWTI 131
            G  ++  E + G+     PV  + KF    + L +G     I+  +++ YY++I  W I
Sbjct: 65  FGYSMIIAETALGRMTKKSPVGAFGKF-GKSKWLSFGGWINAIIPILIVPYYSVIGGWVI 123

Query: 132 FYM 134
            Y+
Sbjct: 124 KYL 126


>UniRef50_Q3V0K1 Cluster: Transporter; n=10; Eutheria|Rep:
           Transporter - Mus musculus (Mouse)
          Length = 423

 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 44/179 (24%), Positives = 93/179 (51%), Gaps = 5/179 (2%)

Query: 374 QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK 433
           +G GL+++ + + ++  P S  W+I+FF+ L  +GL +   L+E +   +      F + 
Sbjct: 97  EGPGLSYVAFSQAISLFPGSSFWAIIFFMSLAIMGLGTMLTLLEGIVLPLQKSISTFAKH 156

Query: 434 KGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKF 493
              V  +V + G+LG L+F++  G Y + L D       ++II + + + +AW+YG ++F
Sbjct: 157 PNLVQVLVCLGGFLGSLVFSSRPGSYVVFLFDDLLVPMVLIIIVVIQNLSLAWLYGIKRF 216

Query: 494 CGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASYGHYVYPMWADAV 552
             ++   +G  S +W   ++ +W  +T   L+ +L   ++    +   +YV   W D++
Sbjct: 217 RAEVFGQLG--SLVW-SPFTFLWSYVTLPTLLVLLTIYFLNLYYSGSPYYV--SWNDSM 270


>UniRef50_Q1MR94 Cluster: Probable sodium-dependent transporter;
           n=1; Lawsonia intracellularis PHE/MN1-00|Rep: Probable
           sodium-dependent transporter - Lawsonia intracellularis
           (strain PHE/MN1-00)
          Length = 455

 Score = 87.4 bits (207), Expect = 1e-15
 Identities = 76/316 (24%), Positives = 138/316 (43%), Gaps = 23/316 (7%)

Query: 233 LLAAWVIVFLCLCKGVQSSGKVVY--FTALFP--YVVLVILFFRGVTLPGAITGILFYLT 288
           LL  W+++ L     ++ + K +    T L P  +++L+I+  R +TLP AI G+ F   
Sbjct: 147 LLWQWLVIILVATIVLRGASKGIEKAATILMPILFILLIIICIRSITLPNAIEGLRFLFM 206

Query: 289 PDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFF 348
           PDFS++ + +V   A    FF LS   G ++T  SY K   N    +  V + ++  S  
Sbjct: 207 PDFSKI-DGRVILLAMGLAFFKLSIGMGVMLTYGSYFKDDVNIPYMATKVMLLDLVVSLL 265

Query: 349 AGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLG 408
           +G+ IF V+     E           G GL FI  P V   +P   +++  FF++     
Sbjct: 266 SGIAIFPVVFSFGFE--------PSSGPGLLFITIPAVFDSMPAGQIFTGAFFILAAVAS 317

Query: 409 LDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTN-------SGMYWL 461
             +  +L ET     +D F N  +K   ++ ++    +   +  + N        GM + 
Sbjct: 318 TGAMLSLFETPVAWAIDTF-NLSRKNTTIIIMLFFIAFGAPVALSENILKHITIFGMNFF 376

Query: 462 QLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITP 521
           QL D  ++N  + +     CI + +++  +     I       ++  + L     R +TP
Sbjct: 377 QLYDFLSSNILMPLGGFFLCIFVGYVWNKQMVMHAISNGGTLHNQGLIKLLLFQCRYVTP 436

Query: 522 AALVFILV--FNWIEY 535
             ++ I++  FN   Y
Sbjct: 437 VIILIIMLHGFNLFAY 452



 Score = 58.0 bits (134), Expect = 7e-07
 Identities = 26/111 (23%), Positives = 52/111 (46%), Gaps = 1/111 (0%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           +R ++T +               N+W+FP +   NGG +FL+ + +  ++AGLP+M  E+
Sbjct: 6   KRDSFTSKIGILAATLGSAVGLGNIWKFPTVIGQNGGASFLLIYIIATIVAGLPIMIAEI 65

Query: 85  SFGQYAALGPVAVYNKFCPLFRGL-GYGMVIVSSIVMLYYNLIIAWTIFYM 134
           + G+      V  + K    +  L G+   + +  V+ +Y  +  W   Y+
Sbjct: 66  AIGRSTRANAVEGFKKLSSGYWWLVGFAGTLSTVFVLGFYTEVAGWIYAYI 116


>UniRef50_Q6GC30 Cluster: Transporter; n=16; Staphylococcus|Rep:
           Transporter - Staphylococcus aureus (strain MSSA476)
          Length = 446

 Score = 86.2 bits (204), Expect = 2e-15
 Identities = 63/218 (28%), Positives = 109/218 (50%), Gaps = 13/218 (5%)

Query: 227 LGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFY 286
           LG  + + A  +IV L + KG++ + KV+    LF +++++++  + +TL GA+ G+ F 
Sbjct: 149 LGQGIFIFATMIIVMLGVEKGLEKASKVM-MPLLFVFLIIIVI--KSLTLDGALEGVKFI 205

Query: 287 LTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATS 346
           L P  S++    +   A  Q FF LS    G+IT +SY          ++ + V NI  S
Sbjct: 206 LQPRVSEITADGILF-ALGQSFFTLSLGTTGMITYASYASKDMTIKSSAISIVVMNIFVS 264

Query: 347 FFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLT 406
             AGL IF  +    +E          +G GL F V P V +++ +  L+ + F V+ L 
Sbjct: 265 VLAGLAIFPALHSFGYE--------PQEGPGLLFKVLPMVFSQMHLGTLFYLGFLVLFLF 316

Query: 407 LGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVF 444
             L S  +L+E +  +   +  N ++KK  V+  + VF
Sbjct: 317 AALTSSISLLE-LNVSNFTKNDNTKRKKVAVIGSILVF 353



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 28/112 (25%), Positives = 49/112 (43%), Gaps = 2/112 (1%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           ++  W     F             +W+FPY+    GGGAFL  F +  +  GLPL+ ME 
Sbjct: 5   QQSQWKSSTGFILASAGSAIGLGAMWKFPYMAGIYGGGAFLAMFLIFTIFVGLPLLIMEF 64

Query: 85  SFGQYAALGPVAVYNKFC--PLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYM 134
           + G+        +Y+K         +G+   +   I+  +Y++I  W + Y+
Sbjct: 65  TVGKMGRTYTTQIYSKLTGKKWLNIIGWNGNLAVFILFGFYSVIGGWIVIYI 116


>UniRef50_A3HYF8 Cluster: Sodium-and chloride-dependent transporter;
           n=1; Algoriphagus sp. PR1|Rep: Sodium-and
           chloride-dependent transporter - Algoriphagus sp. PR1
          Length = 461

 Score = 86.2 bits (204), Expect = 2e-15
 Identities = 60/209 (28%), Positives = 102/209 (48%), Gaps = 9/209 (4%)

Query: 237 WVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRG--VTLPGAITGILFYLTPDFSQL 294
           ++++ + +  G  S G       L P + ++I+F  G  VTL GA  GI +YLTPDF+++
Sbjct: 148 FIMMTILIVLGGVSGGIEKASKFLMPVLFIIIIFIAGRSVTLEGAQAGIEYYLTPDFAKI 207

Query: 295 ANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIF 354
            N  V   A  Q FF++S  WG +IT  SY    +N    +  +A  + + +   GL++F
Sbjct: 208 -NPTVILQALGQAFFSMSVGWGLMITFGSYLPKKSNIIQSAGWIAGMDTSVALLGGLMVF 266

Query: 355 SVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFA 414
             +  L    + +       G  L F V P+V   +P   +   LFF++L+   L S  +
Sbjct: 267 PALFALLPGKDPAA------GPALVFDVLPKVFDAMPGGNIIGGLFFILLMVAALTSTIS 320

Query: 415 LMETVTTAILDRFPNFRQKKGWVVFIVAV 443
           ++E     ++D     R++  W V I A+
Sbjct: 321 MLEVPVAYLIDDRKWGRKRSTWTVGIAAM 349



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 39/122 (31%), Positives = 60/122 (49%), Gaps = 8/122 (6%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           ERG W     F            N+WRFPYL   NGGGAF+  + + +++  LPL+F E+
Sbjct: 9   ERGQWGSSLGFIMAAAGSAVGLGNIWRFPYLVGENGGGAFVFVYIICVLLIALPLLFNEI 68

Query: 85  SFGQYAALGPVAVY-----NKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFS 139
           + G+ +   P+        NKF   ++  G   V+V   V  YY++I  WT+ Y+     
Sbjct: 69  ALGRRSGKNPIGAIRETGGNKF---WQSAGVLCVLVCFFVFSYYSVIAGWTVGYIFTEII 125

Query: 140 SI 141
           +I
Sbjct: 126 NI 127


>UniRef50_Q9KG95 Cluster: Sodium-dependent transporter; n=34;
           Bacillales|Rep: Sodium-dependent transporter - Bacillus
           halodurans
          Length = 457

 Score = 85.8 bits (203), Expect = 3e-15
 Identities = 90/355 (25%), Positives = 156/355 (43%), Gaps = 32/355 (9%)

Query: 207 YFTNQVLGLSSGIEET--GEIRLG------MAMCLLAAWV-IVFLCLCKGVQSS---GKV 254
           YF   + G  SG++E   GEI         +A+    A++ IV   + +GV+       V
Sbjct: 111 YFLKAITGQLSGLDEGRYGEIFAETISNPILAISSQFAFLAIVMYVVSRGVKKGIERASV 170

Query: 255 VYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPA 314
           +   ALF  V+ + +  RG+TL GA  G+ F+L PDFS + +  +   A  Q FFALS  
Sbjct: 171 IMMPALF--VLFLAIVIRGLTLDGATEGLAFFLVPDFSTITSETLLY-AMGQSFFALSVG 227

Query: 315 WGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQ 374
              ++T SSY     +    +L + +     +F AG+ IF  +         S     D+
Sbjct: 228 VSVMVTYSSYLSRDESIVQSALSIVMLTFVVAFLAGVAIFPAV--------FSFGMSPDE 279

Query: 375 GAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKK 434
           G  L F V P V  ++P    + + F ++ L   L S F+++E V  AI     + R K 
Sbjct: 280 GPVLLFNVLPSVFDQMPYGAFFLVTFLLLFLFATLTSAFSMLEVVVAAITKGDVSQRPKV 339

Query: 435 GWVV-FIVAVFGYLGGLIFTTNSG--MYWLQLMDKYAANWSVLIIAIGECILIAWI---Y 488
            W++   +   G    L +   S   ++   + D      S +++ IG  ++  ++    
Sbjct: 340 TWLIGLAIFAVGIPSALSYGVWSDVLLFGRTVFDTADFLVSNILMPIGALLIAIFVPLKI 399

Query: 489 GAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITP--AALVFILVFNWIEYKPASYG 541
             E+   +I+       +L+  +W  + R + P   A+VF+ V   + +  A  G
Sbjct: 400 SKERLYEEIKAGASIGKRLFA-IWFILIRYVAPIVIAIVFLDVIGALSFISAVAG 453



 Score = 59.7 bits (138), Expect = 2e-07
 Identities = 27/107 (25%), Positives = 49/107 (45%), Gaps = 2/107 (1%)

Query: 29  WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQ 88
           W+ +  F             +W+FPY+   +GGGAF + F +  ++ GLPL+  E   G+
Sbjct: 5   WSSKLAFILAAAGSAVGLGAIWKFPYVTGTSGGGAFFLIFILFTLLIGLPLLIGEFVIGR 64

Query: 89  YAALGPVAVYNKFCP--LFRGLGYGMVIVSSIVMLYYNLIIAWTIFY 133
                 +  Y    P   + G+G   +    +++ +Y++I  W I Y
Sbjct: 65  STQKNAIESYRAIAPNSSWGGVGKLGIFTCFLLLSFYSVIGGWIIIY 111


>UniRef50_Q8A1L9 Cluster: Na+-dependent transporter; n=8;
           Bacteroidales|Rep: Na+-dependent transporter -
           Bacteroides thetaiotaomicron
          Length = 456

 Score = 85.4 bits (202), Expect = 4e-15
 Identities = 79/267 (29%), Positives = 126/267 (47%), Gaps = 21/267 (7%)

Query: 227 LGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFY 286
           L + + LL    I+   + KG++ S K++  T    +++++IL    VTLPGA  GI F 
Sbjct: 148 LWLVLFLLVTHFIIVKGVEKGIEKSSKIMMPTL---FIIILILVICSVTLPGAGAGIEFL 204

Query: 287 LTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATS 346
           L PDFS++ +  V+  A  Q FF+LS   G L T +SY     N    +  V + +   +
Sbjct: 205 LKPDFSKV-DGNVFLSAMGQAFFSLSLGMGCLCTYASYFSKETNLTKTAFSVGIIDTFVA 263

Query: 347 FFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTR----LPI-SPLWSILFF 401
             AG +IF            SV    D G  L FI  P V  +    +PI + ++S++F+
Sbjct: 264 VLAGFIIFPAA--------FSVGIQPDAGPSLIFITLPNVFQQAFSGVPILAYIFSVMFY 315

Query: 402 VMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVF-GYLGGLIFTTNSG--M 458
           V+L    L S  +L E VT  + + F   R K   +V    +F G L  L      G  +
Sbjct: 316 VLLAMAALTSTISLHEVVTAYLHEEFNFTRGKAARLVTGGCIFLGILCSLSLGVMKGFTI 375

Query: 459 YWLQLMDKYAANWSVLIIAIGE-CILI 484
           + L + D +    + +++ +G  CI I
Sbjct: 376 FGLGIFDLFDFVTAKIMLTLGGLCISI 402



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 30/120 (25%), Positives = 59/120 (49%), Gaps = 2/120 (1%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           +R N+  +               N+WRFPY   N+GG AF++ +   + + GLP++  E 
Sbjct: 5   DRANFGSKLGVILASAGSAVGLGNIWRFPYETGNHGGAAFILIYLGCVFLLGLPILIAEF 64

Query: 85  SFGQYAALGPVAVYNKFCP--LFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIF 142
             G+ +       Y K  P   +R +G   V+ + +++ YY+++  WT+ Y+  + ++ F
Sbjct: 65  LIGRRSRANTAGAYQKLAPGTHWRWVGRMGVLAAFLILSYYSVVAGWTLEYVYEALTNGF 124


>UniRef50_A7HNE0 Cluster: Sodium:neurotransmitter symporter; n=1;
           Fervidobacterium nodosum Rt17-B1|Rep:
           Sodium:neurotransmitter symporter - Fervidobacterium
           nodosum Rt17-B1
          Length = 518

 Score = 85.4 bits (202), Expect = 4e-15
 Identities = 72/290 (24%), Positives = 133/290 (45%), Gaps = 23/290 (7%)

Query: 263 YVVLVILFFRGVTLPGAIT-------GILFYLTPDFSQLANAQVWGDAAVQIFFALSPAW 315
           Y+  +IL  R +TL   +        G+ F  +P +++L N      AA QIFF LS   
Sbjct: 190 YIFAIILLVRALTLGSPVNPEWNPIKGLDFLWSPRWNEL-NWSATLAAAGQIFFTLSLGM 248

Query: 316 GGLITLSSYNKFSNNCYIDSLIVAVSN-IATSFFAGLVIFSV-IGFLAHELNVSVDRVVD 373
           G +   +SY +  ++    ++  A  N  A    AG ++  +   FL  E        + 
Sbjct: 249 GIIQNYASYMRDEDDIVTSAVATASLNEFAEVILAGTIVIPIAFTFLGAE-------GLK 301

Query: 374 QGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK 433
            G GL+FI  P V   +    ++   +F++L   G+ S  A+   +T  + + F   R+K
Sbjct: 302 SGVGLSFIALPNVFRNMAGGQIFGTFWFLLLFFAGITSSIAMFNYLTAFLEEEFGVERKK 361

Query: 434 KGWVVFIVAVFGYLGGL---IFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGA 490
               VF++ + G L      I T  + + +L  +D +   + ++++ + E I   W++ A
Sbjct: 362 GSLFVFLMYIIGGLPVALEPILTKTADLMYLTELDNWVGTYFLVLLGLIEVIAAVWLFKA 421

Query: 491 EKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILVFNWIEYKPASY 540
            K   +I +  G   K+ ++ +  +   ITPA ++ +LVF+ I+Y    Y
Sbjct: 422 -KGLEEINK--GSYWKIPMWFYKLIMSFITPAFIIILLVFSTIDYAKNGY 468



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 39/124 (31%), Positives = 62/124 (50%), Gaps = 16/124 (12%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           +R +W  +               N WRFPY    NGGGAF+IP+ +  +  G+PL+ +E 
Sbjct: 3   KREHWGSKIGLILAMAGNAIGLGNFWRFPYQAAKNGGGAFMIPYFIAFLFMGIPLLIIEW 62

Query: 85  SFGQY------AALGPV-------AVYNKFCPLFRGLGYGMVIVSSIVML--YYNLIIAW 129
           + G+Y        LGP+       +V +KF  +   L  G + +S +++L  YYN +I W
Sbjct: 63  AQGRYGGKYGHGTLGPMIYLQAKESVGHKFAKVLGALA-GAIALSVVILLNSYYNHVIGW 121

Query: 130 TIFY 133
           T+ Y
Sbjct: 122 TLGY 125


>UniRef50_UPI0000DB7B68 Cluster: PREDICTED: similar to CG8291-PA,
           isoform A, partial; n=1; Apis mellifera|Rep: PREDICTED:
           similar to CG8291-PA, isoform A, partial - Apis
           mellifera
          Length = 835

 Score = 85.0 bits (201), Expect = 5e-15
 Identities = 109/436 (25%), Positives = 179/436 (41%), Gaps = 62/436 (14%)

Query: 225 IRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFR--GVTLPGAITG 282
           ++  +A  L   W+IVF+ L KG++S GKVVY   L P    ++L  +  G+T PG+I  
Sbjct: 151 LKFQLAFNLAVVWMIVFVSLSKGLKSYGKVVYVFTLVPVFGTLVLCTKLLGLTPPGSIHQ 210

Query: 283 ILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSN 342
            LF  T       N + W  A++++F          + ++++NK  +    D+ +V V  
Sbjct: 211 -LFPATVWTEFFINGKSWLAASIEVFLTWGLFGAAAMQIAAHNKHKHLLQRDTSLVIVLT 269

Query: 343 IATSFFAG---------------LVIFSVIG-------FLAHELNVSVDRVVDQGAG--- 377
           IA    A                + I S  G       F+AH   +  +RV   GA    
Sbjct: 270 IAVLLLAAFLANTCVQVLRHHGYIYIPSSFGYNSTPERFMAHTSFIVGERVTRPGADFSI 329

Query: 378 --------LAFIVYPEVVTRL---PISPLWSILFFVMLLTLGLDSQFALMETVTTAILDR 426
                   L+  + P  +  L    +SP W+ILF+ +L+  G+  Q A+   V T I+  
Sbjct: 330 ESGYQVLRLSTELVPATLALLGTEQVSPFWAILFYFILILFGIAQQLAIWHCVITGIM-- 387

Query: 427 FPNFRQKKGW---VVFIVAVFGYLGGLIFTTNSGMYWLQLMD-KYAANWSVLIIAIGECI 482
             N +  K W   V F      Y+ GL   T  G++ +  +D      W ++I+ + +  
Sbjct: 388 AINTKMMKLWETTVTFFSCACAYILGLPMATELGIHVVYYLDYTIGGTWWIIILYLVQVG 447

Query: 483 LIAWIYG----AEKFCGDIQRMIGRQSKLWV-YLWSAMWRIITPAALVF--ILVFNWIEY 535
            +  + G     E    ++    GR  + W   L S  W +I P  L+   I +F    +
Sbjct: 448 AVFAVRGRPHSGEAVVAELFPPTGRCLRHWAGPLLSFTWNVILPVILMVLSITIFKNAGF 507

Query: 536 KPA-SYGHYV---YPMWADAVGWTXXXXXXXXXXXXXXDQIC----SGPDDLTIMEKARV 587
           +   SY   V   + +WA  +G T               Q C    +GP D  I ++ ++
Sbjct: 508 RELYSYRRTVKEYWTIWAKQLGATIQLIPILTIPAVAIIQTCRYLNNGPPD--IFDRIQL 565

Query: 588 LARPTEEWGQAGSTAT 603
           L RP+ E      T T
Sbjct: 566 LYRPSLESDDPRDTQT 581



 Score = 54.4 bits (125), Expect = 9e-06
 Identities = 30/126 (23%), Positives = 56/126 (44%), Gaps = 2/126 (1%)

Query: 10  DEEKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFT 69
           D  + +    +E     G W                  N+ RF  L    G   F++ F 
Sbjct: 9   DRNEDRGEDEDEDANPLGKWPHALSPALACLSCTLGLFNISRFSILSIQFGAN-FIVQFL 67

Query: 70  VMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAW 129
           ++ +I G+PL+ + +  GQ  A G V ++ K  P+F+G+G  ++I  + + +Y  + I+W
Sbjct: 68  ILSLILGIPLLTLHVCLGQRLAAGSVNMW-KISPVFQGVGIALLIAQAFIGIYSVVGISW 126

Query: 130 TIFYMT 135
              Y +
Sbjct: 127 MFVYFS 132


>UniRef50_Q8D8U8 Cluster: Na+-dependent transporter of the SNF
           family; n=18; Bacteria|Rep: Na+-dependent transporter of
           the SNF family - Vibrio vulnificus
          Length = 475

 Score = 84.6 bits (200), Expect = 7e-15
 Identities = 90/335 (26%), Positives = 152/335 (45%), Gaps = 32/335 (9%)

Query: 209 TNQVLGLSSG--IEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVL 266
           T   +G S G  I +  +  L M + LL   VIV   +  G++ +GKV+    LF  ++L
Sbjct: 127 TPDTIGSSFGAFISDPVQPLLWMGVYLLLNIVIVMRGVSGGIEKAGKVL-MPLLF--IIL 183

Query: 267 VILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNK 326
           +I+  +G+ LPGA+ G+ F   PDFS++ ++ V   A  Q FF+LS   G ++T  SY K
Sbjct: 184 IIVSVKGLMLPGAMAGLEFLFMPDFSKV-DSNVVLAALGQAFFSLSLGMGCMMTYGSYLK 242

Query: 327 FSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEV 386
              N    + +V   +   +  AG+ +F  +     E           G GL F+V P++
Sbjct: 243 KQENLVQTTGMVTAMDTGVAILAGVAMFPAMFAFGME--------PAAGPGLVFVVVPQL 294

Query: 387 VTRL--PISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQ----KKGWVVFI 440
            + +   I  + ++LFF+ L    L S  +L+E V + ++D     R         V+  
Sbjct: 295 FSEMGGVIGLVLALLFFIGLTVAALTSSVSLLEVVVSYLIDEKGMKRSTAVISSSIVMAS 354

Query: 441 VAVF-----GYLGGLIFTTNSGMYWLQLMDK-YAANWSVLIIAIGECILIAWIYGAEKFC 494
           + +F     G +G  +F T +   +  L DK + A   +L+     CI   W    E   
Sbjct: 355 LCIFASLSLGGVGPKLFDTGAFDIFDLLTDKIFLAVGGMLV-----CIFAGWRLSREDLE 409

Query: 495 GDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILV 529
            +I    G+ S     +W  + + I P A+  + V
Sbjct: 410 KEITN-DGKVSFPLFGVWYNLVKYIIPVAIAIVAV 443



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 25/109 (22%), Positives = 45/109 (41%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           R  W  +  F            N+W+FPY    +GGGAF+  +   ++  G  +M  E +
Sbjct: 9   RDTWGSKLGFVMAAAGSAVGLGNIWKFPYTAGESGGGAFVAIYLFFVIFIGFSVMLTEFA 68

Query: 86  FGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYM 134
            G+   L  V  +      +   G   V    ++M +Y ++  W + Y+
Sbjct: 69  IGRKTGLSAVGAFKSTDRRWTFTGVLGVFSGLLIMGFYPVVGGWALAYI 117


>UniRef50_Q81S42 Cluster: Sodium-dependent transporter; n=13;
           Bacillaceae|Rep: Sodium-dependent transporter - Bacillus
           anthracis
          Length = 445

 Score = 84.6 bits (200), Expect = 7e-15
 Identities = 80/311 (25%), Positives = 145/311 (46%), Gaps = 20/311 (6%)

Query: 227 LGMAMCLLAAWVIVFLCLCKGVQSSGKVV--YFTALFPYVVLVILFFRGVTLPGAITGIL 284
           L +   LL   + +F+ + KGVQ+  + V  YF     +V+  +L  R +TL GA  G+ 
Sbjct: 141 LAVGSQLLFILITIFI-VSKGVQNGVEKVNKYFMPAL-FVLFFVLIVRALTLDGAGEGVR 198

Query: 285 FYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIA 344
           F+L PDFS +  ++V   A  Q FF+LS     ++T SSY     +    +  +    + 
Sbjct: 199 FFLQPDFSNV-TSEVILYAMGQSFFSLSVGVAVMVTYSSYLPKEESLPRSAFSIVGLTLV 257

Query: 345 TSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVML 404
            +  AGL IF V+   A  L  S      QG GL FIV P + +++    ++ ++F ++ 
Sbjct: 258 ITLLAGLAIFPVV--FAFGLEPS------QGPGLLFIVLPAIFSKMAFGKVFFVIFLLLF 309

Query: 405 LTLGLDSQFALMETVTTAILDRFPNFRQKKGWVV-FIVAVFGYLGGLIFTTNSGMYWLQL 463
               + S  +++E    ++  +    R+K   +V  ++ V G    L F   S +     
Sbjct: 310 FFATITSAISMLEISVASLTSKGKGKREKMALIVGLLIFVVGVPSALSFGILSDLKIFGK 369

Query: 464 MDKYAANWSVLIIAIGECILIAWIYGAEKFCGDI-QRMIG----RQSKLWVYLWSAMWRI 518
                A+++V  + +   +L+  I+   K   D+  + +G    +  KL+V LW  + R 
Sbjct: 370 TVFDLADYAVSNVLMPLGVLLVSIFVPLKMKKDVLMKELGVSKNKGYKLFV-LWLFLLRF 428

Query: 519 ITPAALVFILV 529
           I P A++ + +
Sbjct: 429 IAPIAIIIVFL 439



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 29/108 (26%), Positives = 50/108 (46%), Gaps = 2/108 (1%)

Query: 29  WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQ 88
           WT +  F             +W+FPY+    GGGAF + F    ++ GLPL+  E   G+
Sbjct: 6   WTSKLGFVLAAAGSAIGLGAIWKFPYMAGIGGGGAFFLIFIGFTLLIGLPLLLAEFVIGR 65

Query: 89  YAALGPVAVYNKFCP--LFRGLGYGMVIVSSIVMLYYNLIIAWTIFYM 134
                 V  Y +  P  L+  LG   ++   I++ +Y+++  W + Y+
Sbjct: 66  STQKEAVDAYREIAPKTLWPWLGKLGIVTCFILLSFYSVVGGWILLYL 113


>UniRef50_Q73R42 Cluster: Sodium-dependent transporter, putative;
           n=6; Bacteria|Rep: Sodium-dependent transporter,
           putative - Treponema denticola
          Length = 441

 Score = 84.6 bits (200), Expect = 7e-15
 Identities = 66/254 (25%), Positives = 112/254 (44%), Gaps = 19/254 (7%)

Query: 247 GVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQ 306
           G++   K++  T    + + +IL  R  TLP A+ G  F    D+S LAN + W  A  Q
Sbjct: 170 GIEKINKIMMPTF---FTLFIILAIRVATLPKALDGYKFLFKTDWSALANIKTWVFALGQ 226

Query: 307 IFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNV 366
            FF+LS A  G +   SY   S +    +   A+ +   +  A LVI   +   A+ L  
Sbjct: 227 AFFSLSLAGSGTVVYGSYLNDSEDARTSAKYTAIFDTLAAMIAALVIIPAV--FAYGLEP 284

Query: 367 SVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDR 426
           +       G  L FI  P +   +P   L+SI+FF+ +L  G+ S   L ET    +  +
Sbjct: 285 AA------GPPLMFITMPMIFKEMPAGTLFSIIFFIAVLFAGITSLINLYETPVELMQQK 338

Query: 427 FPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGM-YWLQLMDKYAANWSVLIIAIGECILIA 485
           F N  +K    + IV   G+  GL+    + +  W+ ++  Y      L+      ++  
Sbjct: 339 F-NLSRKA--ALAIVLGLGFAVGLVVEDGNVLGTWMDVISIYIIPLGALLAG----VMFF 391

Query: 486 WIYGAEKFCGDIQR 499
           W+ G +    ++ +
Sbjct: 392 WVAGKDFVLNEVSK 405



 Score = 54.4 bits (125), Expect = 9e-06
 Identities = 32/124 (25%), Positives = 56/124 (45%), Gaps = 7/124 (5%)

Query: 22  IEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMF 81
           IE +R  +  ++ F            N+W FP+     GG AFLIP+ + + + G   + 
Sbjct: 4   IESKRDQFNSKWGFILACIGSAVGMGNIWLFPFRVGQFGGAAFLIPYIIFVAVIGYTGVV 63

Query: 82  MELSFGQYAALGPVAVYNKFCPLFRG------LGYGMVIVSSIVMLYYNLIIAWTIFYMT 135
            E+ FG+    GP   + K     RG      +G+  VI S  + + Y +++ W I +  
Sbjct: 64  EEMCFGRAMKTGPHGAFLK-ATRMRGSEAGNYIGWIPVIGSLGIAIGYTVVVGWIIRFAV 122

Query: 136 VSFS 139
            +F+
Sbjct: 123 GAFT 126


>UniRef50_UPI00015B5071 Cluster: PREDICTED: similar to sodium/chloride
            dependent transporter; n=1; Nasonia vitripennis|Rep:
            PREDICTED: similar to sodium/chloride dependent
            transporter - Nasonia vitripennis
          Length = 1583

 Score = 84.2 bits (199), Expect = 9e-15
 Identities = 81/358 (22%), Positives = 146/358 (40%), Gaps = 26/358 (7%)

Query: 10   DEEKSKAPLSEEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFT 69
            D+E+ +    +E  P  G W                  N+ RF  L    G   F++ F 
Sbjct: 669  DDERGEDEDEDENNP-LGRWPHALSPALACLGCTLGLFNISRFAILSIQFGAN-FIVQFL 726

Query: 70   VMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAW 129
            ++ ++ G+PL+ +++  GQ  A G V ++ K  PLF+G+G  ++   + + +Y  + ++W
Sbjct: 727  ILSLVIGIPLLTLQVCLGQRLAAGAVDMW-KISPLFQGVGIALLAAQAFIGIYSIVGVSW 785

Query: 130  TIFYMTVSFSSIFYQLPWQNCKAEWSTKHCYSYEEADECEAQNGTYYLRQCFNQSYSVSH 189
               Y   SF +   +  W    A +      +          NG        N SY +S 
Sbjct: 786  MFVYFRDSFITKQDRYRWAEPFALYREDIRPTNSPGAAGSGPNGP----GNNNSSYKLSE 841

Query: 190  NITALAKTALRRPPAEEYFTNQVL---GLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCK 246
             +              +YF   VL    L+        ++  +A  L   W+IVF+ L K
Sbjct: 842  TV-------------PDYFNGAVLQRHHLNEPDPGVVTLKFQVAFNLAVVWMIVFVSLSK 888

Query: 247  GVQSSGKVVYFTALFPYVVLVILFFR--GVTLPGAITGILFYLTPDFSQLANAQVWGDAA 304
            G++S GKVVY   L P    ++L  +  G+T PG++   LF  T       N + W  A+
Sbjct: 889  GLRSYGKVVYVFTLVPIFGTLVLCTKLLGLTPPGSLHQ-LFPGTVWAEFFINGRSWVAAS 947

Query: 305  VQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAH 362
             ++F          + ++++NK  +    D+ +V V        A  +  + +  L +
Sbjct: 948  SEVFLTWGLLGAAAMQIAAHNKHKHLLQRDTSLVVVLTFVVLLLAAFLANTCVQILKY 1005



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 51/222 (22%), Positives = 93/222 (41%), Gaps = 23/222 (10%)

Query: 392  ISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGW---VVFIVAVFGYLG 448
            +SP W++LF+ +L+  G+  Q A+   V T I+    N +  K W   + F      Y+ 
Sbjct: 1089 VSPFWAVLFYFILILFGIAQQLAIWHCVITGIM--AINTKMMKLWETTITFFSCACAYIL 1146

Query: 449  GLIFTTNSGMYWLQLMD-KYAANWSVLIIAIGECILIAWIYG----AEKFCGDIQRMIGR 503
            GL   T  G+Y +  +D      W +L++ + +   +  + G     +    ++    GR
Sbjct: 1147 GLPMATEFGIYVVYYLDYTVGGAWWILVLYLVQVAAVFAVRGRPHTGDAVVAELFPPTGR 1206

Query: 504  QSKLWV-YLWSAMWRIITPAALVF--ILVFNWIEYKPA-SYGHY---VYPMWADAVGWTX 556
              + W   L S  W ++ P  L+   I +F    Y+   +Y       + +WA  +G + 
Sbjct: 1207 CLRYWAGPLLSFTWNVVLPITLMVLSITIFKSTGYRELYTYRRMNKDYWSIWARQLGASI 1266

Query: 557  XXXXXXXXXXXXXDQIC----SGPDDLTIMEKARVLARPTEE 594
                          Q C    +GP D  I ++ ++L RP+ E
Sbjct: 1267 QLIPILMIPVVAVIQTCRYLNNGPPD--IFDRIQLLYRPSLE 1306


>UniRef50_A4A5L0 Cluster: Sodium-and chloride-dependent transporter;
           n=2; unclassified Gammaproteobacteria|Rep: Sodium-and
           chloride-dependent transporter - Congregibacter
           litoralis KT71
          Length = 451

 Score = 84.2 bits (199), Expect = 9e-15
 Identities = 85/311 (27%), Positives = 138/311 (44%), Gaps = 24/311 (7%)

Query: 228 GMAMCLLAAWVIVFLCLCKGVQSS-GKVVYFTALFPYVVLVILFFRGVTLPGAITGILFY 286
           GM    LA   I  L +  GV++   + V       + +LV L    V   G    + + 
Sbjct: 151 GMLFWTLAGLAITGLIIFAGVKNGIERAVTIMMPLMFALLVALAGFNVFAGGFGEAVAWL 210

Query: 287 LTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATS 346
            TPDFS+++ A V   A  Q FF++    GG++T  SY   S +     LI+ +++   +
Sbjct: 211 FTPDFSKVSFATVLA-AIGQAFFSIGVGMGGMMTYGSYLPRSISISQSVLIIVIADTGVA 269

Query: 347 FFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLT 406
             AGLVIF  +       N  +D     GAGL F   P    ++P   ++++LFF+ML T
Sbjct: 270 LLAGLVIFPAV------FNYGLDPAA--GAGLIFQTLPVAFAQMPGGYIFAVLFFLMLAT 321

Query: 407 LGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDK 466
            G+ S   L+E+V   I + +   R K   +V  V     L  L   + + M  L+L D+
Sbjct: 322 AGITSMVGLVESVNAWIEEHYGVSRHKSAMIV--VGSIAVLSILSILSYNVMDELRLGDR 379

Query: 467 Y---AANW--SVLIIAIGE---CILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRI 518
               AA++  + +++ +G     I   W    E F  +    +G        +W  + R 
Sbjct: 380 NFNDAADYFSNQILLPLGGLFIAIFAGWFMRRE-FSREEFTTLGETG---YAIWYFLIRY 435

Query: 519 ITPAALVFILV 529
           + P AL+ I V
Sbjct: 436 VVPPALLVIFV 446



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 33/134 (24%), Positives = 68/134 (50%), Gaps = 6/134 (4%)

Query: 28  NWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFG 87
           +WT RF F            N+WRFPY+   NGG AF++ +     + G+P++  EL  G
Sbjct: 10  HWTSRFAFLMASVGFAVGLGNIWRFPYVTGENGGAAFVLIYLGCAFLIGVPILMAELMIG 69

Query: 88  QYA-ALGPVAVYNKF-----CPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSI 141
           +   A  P+A+ N          +R +G   ++ +  + + Y++++ W ++Y+  + ++ 
Sbjct: 70  RRGDAAPPIAMDNVARESGRSSQWRWVGGMGLLAAFTIEIVYSVVVGWVLWYLYKAITTG 129

Query: 142 FYQLPWQNCKAEWS 155
           F  +   N +A+++
Sbjct: 130 FADVDALNAEAQFT 143


>UniRef50_A7HET8 Cluster: Sodium:neurotransmitter symporter
           precursor; n=1; Anaeromyxobacter sp. Fw109-5|Rep:
           Sodium:neurotransmitter symporter precursor -
           Anaeromyxobacter sp. Fw109-5
          Length = 442

 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 89/341 (26%), Positives = 154/341 (45%), Gaps = 29/341 (8%)

Query: 191 ITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQS 250
           + A+A+ A+ R  A ++        S G   T  +   +AM L  A  IV   +  G++ 
Sbjct: 114 LVAVARGAVERDTAAQF----AAAASGGAAVTWHL---VAMALTVA--IVAGGVRGGIER 164

Query: 251 SGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFA 310
           +  +V   ALF  V+L+ L     TLP    G  FYL PD +++     +  A  Q FF+
Sbjct: 165 AS-LVLMPALF--VLLIALAAWAATLPDGGAGYAFYLRPDPARIWRLDTFTSAVGQAFFS 221

Query: 311 LSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDR 370
           LS   G ++T +SY +   +   +  ++A+++ + +F  GLV F ++    ++  +   +
Sbjct: 222 LSLGMGAMLTYASYLQKGGSLVREGFVIALADGSVAFAGGLVTFPIV----YQFGLQ-GQ 276

Query: 371 VVDQGAGLAFIVYPEVVTRL-PISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPN 429
           V +   G  FI  P     L     +    FF+ LL   L S  +L+E +  A++ R   
Sbjct: 277 VGESTVGALFIALPHAFATLGATGRIVGTAFFLALLIAALTSAISLLEVLVDAVVARTGW 336

Query: 430 FRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIY- 488
            R++    V +      L G+    +  + WL   D+ A N  +++  +   IL  WI+ 
Sbjct: 337 SRRR---AVVLAGGATALAGVPAALD--LRWLGAADRIAGNLLLVVGGLIIAILTGWIWT 391

Query: 489 GAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILV 529
           GA+    D      R  + W++L     R+  PAAL  +LV
Sbjct: 392 GADAELAD-GFPHPRVRRAWIWL----LRVAIPAALALVLV 427



 Score = 63.7 bits (148), Expect = 1e-08
 Identities = 33/113 (29%), Positives = 53/113 (46%), Gaps = 2/113 (1%)

Query: 23  EPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFM 82
           EP R +W     F            N+WRF YL   +GG AF++ + V++V+ G PL+  
Sbjct: 3   EP-RPSWHSNVGFLLAAVGSAVGLGNLWRFAYLASESGGAAFVLVYLVVIVLVGAPLLVA 61

Query: 83  ELSFGQYAALGPVAVYNKFC-PLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYM 134
           EL+ G+ A  G      +        +G   V+    ++ YY++I  WT  Y+
Sbjct: 62  ELAMGRSAREGAFRAPGRLVGRRLEWVGALFVLTGFAILSYYSVITGWTARYL 114


>UniRef50_A6PLC6 Cluster: Sodium:neurotransmitter symporter
           precursor; n=1; Victivallis vadensis ATCC BAA-548|Rep:
           Sodium:neurotransmitter symporter precursor -
           Victivallis vadensis ATCC BAA-548
          Length = 531

 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 73/277 (26%), Positives = 116/277 (41%), Gaps = 32/277 (11%)

Query: 236 AWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLA 295
           A ++++  +  G++   K++  T  F   +LV L  RGVTL GA  G+ F+LTPDFS+L 
Sbjct: 197 AALMIWCGIRNGIERWSKILMPTLFF---LLVALLLRGVTLSGASKGVAFFLTPDFSKLT 253

Query: 296 NAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFS 355
            A    +A    F+ LS      IT  SY     N +  +L V + +   +  AGL IF 
Sbjct: 254 AAGAL-EALGHAFYTLSLGMAITITYGSYLGRDKNIFTSALWVVLLDTGAALLAGLAIFP 312

Query: 356 VIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLP--ISPLWSILFFVMLLTLGLDSQF 413
            +  +  +           G  L F V P      P     LW+ LFF+ML    L S  
Sbjct: 313 AVFAMGFD--------PSDGPSLIFKVLPATFYNFPGGFGWLWAGLFFLMLTIAALTSAA 364

Query: 414 ALMETVTTAILDRFPNFRQKKGWVVFI-VAVFGYLGGL-----------------IFTTN 455
           +L E   T ++D+    R     + ++ +  FG L  +                 +F   
Sbjct: 365 SLFECGVTFLIDQLGLKRSVAVILCYVGIGGFGVLTSVSCATWEHLPGVHGVLEYVFGEV 424

Query: 456 SGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEK 492
               W  L+D   +NW + +  +   I + W++   K
Sbjct: 425 KSKNWFVLLDYVTSNWMLPLSGLFTAIFVGWVWTTRK 461



 Score = 57.6 bits (133), Expect = 9e-07
 Identities = 22/74 (29%), Positives = 36/74 (48%)

Query: 25 ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
          +R NW     F            NVW+FPY+   NGGGAF++ +   + + G+P+M  E+
Sbjct: 5  KRENWGSTLGFVLAIAGSAIGLGNVWKFPYITGQNGGGAFVLVYLFCIFLLGMPIMLCEM 64

Query: 85 SFGQYAALGPVAVY 98
          + G+     P   +
Sbjct: 65 AIGRKTRQNPYGAF 78


>UniRef50_Q5QY70 Cluster: Na+-dependent transporter of the SNF
           family; n=11; Proteobacteria|Rep: Na+-dependent
           transporter of the SNF family - Idiomarina loihiensis
          Length = 472

 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 62/223 (27%), Positives = 110/223 (49%), Gaps = 11/223 (4%)

Query: 228 GMAMCLLAAWVIVFLCLCKGV-QSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFY 286
           G    L+A  +IV + L  GV Q   K   F     +++L++L    ++L  A+ G+ FY
Sbjct: 141 GFVGFLIAVTIIVNVILLGGVRQGIEKAAKFLMPALFIMLILLVIFVLSLDNAVLGLEFY 200

Query: 287 LTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATS 346
           L PDFS++  + + G A  Q FF+LS   G LIT  SY    ++      +VA+++ A +
Sbjct: 201 LVPDFSKIDGSVING-ALSQAFFSLSLGMGILITYGSYFSRRDDIVTSGKLVALTDTAVA 259

Query: 347 FFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLP------ISPLWSILF 400
           F AGL+    I   A   N + D + D    + F  +P++   L        + + + +F
Sbjct: 260 FTAGLMTLPAI--FAINPNTNPDSLSDSSVSMIFSFFPQIFIALEGVVGYVGASIAATIF 317

Query: 401 FVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAV 443
           F++     + S  +++E  T A++++     +KK  +V  +AV
Sbjct: 318 FLLTFIAAITSLVSILEVPTAAVIEQ-AKISRKKALLVMGIAV 359



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 29/113 (25%), Positives = 49/113 (43%), Gaps = 3/113 (2%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           +R  ++ +  F            N+  FP     NGGGAFLI + + +    +P+M  E+
Sbjct: 4   QRDQFSSKIGFILAAAGSAVGIGNLVGFPVAATKNGGGAFLIIYALFVAFICVPVMLAEM 63

Query: 85  SFGQYAALGPVAVYNKFCPLFRG---LGYGMVIVSSIVMLYYNLIIAWTIFYM 134
             G+ A   P+  Y    P  +G    G   VI   ++ ++Y +I  W   Y+
Sbjct: 64  GLGRRAQKSPLGSYKALSPNNKGWHLAGLLAVITPFMIAVFYMVITVWIFGYL 116


>UniRef50_Q3A7I2 Cluster: Na+-dependent transporters of the SNF
           family; n=6; Desulfuromonadales|Rep: Na+-dependent
           transporters of the SNF family - Pelobacter carbinolicus
           (strain DSM 2380 / Gra Bd 1)
          Length = 468

 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 78/314 (24%), Positives = 141/314 (44%), Gaps = 32/314 (10%)

Query: 237 WVIVFLCLCKGVQSSG--KVV--YFTALFPYVV--LVILFFRGVTLPGAITGILFYLTPD 290
           W  +F+ LC G+   G  K +  +   L P ++  LV+LF  G+   GA   + F   PD
Sbjct: 159 WHFIFISLCLGIVIGGVQKGIERWSKILMPILLGLLVLLFVNGMLSDGARQALNFMFRPD 218

Query: 291 FSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAG 350
           F +L    V  +A    FF LS     +IT  SY    ++ +   L +A+ +   +  AG
Sbjct: 219 FQKLNPGAVL-EALGHAFFTLSLGMAAMITYGSYLSRQDSLFGSGLRIALLDTGIALMAG 277

Query: 351 LVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLD 410
           L IF ++         S       G GL F   P V + LP   + ++LFF++L    L 
Sbjct: 278 LAIFPIV--------FSAGMQPGAGPGLVFQTIPVVFSNLPGGNILALLFFLLLAFAALT 329

Query: 411 SQFALMETVTTAILD-RFPNFRQKKGWVVFIVAVFG--------YLGGLIFTTNSGMYWL 461
           S  +L+E+    ++D R    +Q   ++  +  V G         LG L    + G++  
Sbjct: 330 SAISLLESQVAYLIDERGWGRKQATAFLAILAFVVGIPSALSSNLLGHLTPIADLGVF-- 387

Query: 462 QLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVY-LWSAMWRIIT 520
             +D  A+N+ + +  +   + + W +  ++   + + ++   S  W+Y  W  + R + 
Sbjct: 388 DSIDLIASNYLLPVSGLLTALYVGWFWSGQE---EKEELLAGGSG-WIYPTWHFLIRFVA 443

Query: 521 PAALVFILVFNWIE 534
           P A V +++++ IE
Sbjct: 444 PVA-VGVILYSKIE 456



 Score = 75.8 bits (178), Expect = 3e-12
 Identities = 33/121 (27%), Positives = 65/121 (53%), Gaps = 5/121 (4%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           R  W  R  F            N+W+FPY+  NNGGGAF++ + V + + GLP+M  EL 
Sbjct: 8   RAQWGSRIGFILAAAGSAVGLGNIWKFPYITGNNGGGAFVLVYLVCIALVGLPIMIAELM 67

Query: 86  FGQYA---ALGP-VAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSI 141
            G++    A+G  +++  +  P ++  G+  ++ + +++ YY+++  WT+ ++  +    
Sbjct: 68  IGRHTRRDAVGAFISLEGRRSP-WQIAGWVSILAAFVILSYYSVVAGWTLDFILRALQGA 126

Query: 142 F 142
           F
Sbjct: 127 F 127


>UniRef50_A6GC50 Cluster: Probable sodium-dependent transporter;
           n=1; Plesiocystis pacifica SIR-1|Rep: Probable
           sodium-dependent transporter - Plesiocystis pacifica
           SIR-1
          Length = 456

 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 34/118 (28%), Positives = 62/118 (52%), Gaps = 3/118 (2%)

Query: 23  EPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFM 82
           +  RG W  +  F            NVW+FPY+   NGGG F+I + + +V+ GLP+M  
Sbjct: 3   QERRGEWGSKIGFILAAAGSAVGLGNVWKFPYITGENGGGLFVIIYLICIVLVGLPIMIG 62

Query: 83  ELSFGQYAALGPVAVYNKF---CPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVS 137
           E+  G+     PV  + K      L++G+G+  V+   +++ YY+++  W + Y+ ++
Sbjct: 63  EVMLGRMTQRSPVGAFRKLDGEKSLWQGVGWLGVLSGFVILSYYSVVAGWALEYVVIA 120



 Score = 79.8 bits (188), Expect = 2e-13
 Identities = 71/296 (23%), Positives = 128/296 (43%), Gaps = 25/296 (8%)

Query: 246 KGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAV 305
           KGV+ + +V+    L  ++ L++      TL G   G  F       +L    +  +A  
Sbjct: 168 KGVEIAARVLMPLLLLMFLALLVY---ATTLEGFGEGFNFVFGFHTDKLGAGSIL-EALG 223

Query: 306 QIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELN 365
             FF LS   G ++T  SY +  ++    S+ + + +   +  A LV+F +      E  
Sbjct: 224 HSFFTLSVGMGAMLTYGSYLRKDDDIIGASVAITIIDTLVAIMACLVLFPITFTYGME-- 281

Query: 366 VSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILD 425
                  + G  L F   P    ++P S +W+++FF++L+   L S  +L+E  +   +D
Sbjct: 282 ------PEAGPSLVFTNIPMAFAQIPGSTIWALIFFLLLVFAALTSAISLLEVCSAYFVD 335

Query: 426 RFPNFRQKKGWVV-FIVAVFGYLGGLIFTT---NSGM------YWLQLMDKYAANWSVLI 475
                R     V    + + G    L F+T    SGM       W  L D  ++NW + +
Sbjct: 336 ELGWSRTLAVPVCGLTITLLGVPSALTFSTATFGSGMEAAIGKSWFDLFDYVSSNWMLPL 395

Query: 476 IAIGECILIAWIYG--AEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILV 529
             +G  +  AW  G  A +   +    +G+   L+V LW  + R + PAA+V +++
Sbjct: 396 CGLGISVFAAWKLGDEARRVQFEAGSTLGKLQGLYV-LWLQVLRYVVPAAIVVVML 450


>UniRef50_UPI00015563FA Cluster: PREDICTED: hypothetical protein,
           partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
           hypothetical protein, partial - Ornithorhynchus anatinus
          Length = 392

 Score = 82.6 bits (195), Expect = 3e-14
 Identities = 42/102 (41%), Positives = 59/102 (57%)

Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322
           Y+VL+ L  RG+ L GA  G+   L    S L +  VW  A  Q+FFAL   +G ++  +
Sbjct: 1   YLVLLCLLIRGLLLDGANAGLKHMLQTQPSALLSIPVWRRAGTQVFFALGLGFGSVVAFA 60

Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHEL 364
           SY    NNC  D+ +VA  N+ATS  A LV+++V+GF A  L
Sbjct: 61  SYTPRENNCARDAWVVAYINLATSLLATLVVYTVLGFRATTL 102



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 29/75 (38%), Positives = 44/75 (58%), Gaps = 5/75 (6%)

Query: 360 LAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETV 419
           L  ELN  V+     G GLAF+V+ E +T  P +P W++LFF+MLL LGL +    ++ +
Sbjct: 166 LEEELNKGVE-----GPGLAFVVFTEALTLFPGAPFWAVLFFLMLLNLGLSTMLGTLQGI 220

Query: 420 TTAILDRFPNFRQKK 434
            T + D F   R+ +
Sbjct: 221 LTPLQDAFHLLRRHR 235


>UniRef50_Q1N557 Cluster: Sodium-dependent transporter, NSS family
           protein; n=2; Proteobacteria|Rep: Sodium-dependent
           transporter, NSS family protein - Oceanobacter sp. RED65
          Length = 442

 Score = 82.2 bits (194), Expect = 4e-14
 Identities = 36/117 (30%), Positives = 62/117 (52%)

Query: 22  IEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMF 81
           I+ +R  W+    F            N+WRFPY+   NGGGAFL+ + + L++  LP+M 
Sbjct: 8   IKQDRQQWSSEPAFIASMAGAAVGLGNLWRFPYMMGENGGGAFLVAYLIALIVVVLPIMM 67

Query: 82  MELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSF 138
           +E++ G+ +  G V  + K     R  G+ +V+++  +  YY +I  WT+ Y   +F
Sbjct: 68  LEVAAGRLSKGGAVHTFGKINRFGRYYGWFVVLITVAITSYYLVITGWTLGYTVDAF 124



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 79/314 (25%), Positives = 138/314 (43%), Gaps = 36/314 (11%)

Query: 229 MAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILF--FRGVTLPGAITGILFY 286
           +A+ LLA  +++     K ++++ K+     L P ++LVI++  F      G      F+
Sbjct: 145 IAVTLLAGAILIKGV--KAIETASKI-----LMPVLLLVIIYLVFEASQTSGWSQAKDFF 197

Query: 287 LTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATS 346
              D+S+L N ++W  A  Q F+ L+   G LIT  S+     N     LIVA +  + +
Sbjct: 198 FVVDWSRLLNVELWAFAFGQAFYTLAIGQGYLITYGSFIPRDTNVPRACLIVAGTETSIA 257

Query: 347 FFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLT 406
             AG +IF  +         S     D G+ LAF+  P+V   +      ++LFF +   
Sbjct: 258 LLAGWMIFPFL--------FSFGMQPDAGSQLAFVTLPQVFASIDGGAYLAMLFFSLFFA 309

Query: 407 LGLDSQFALMETVTTAILDRFPNFR-QKKGWVVFIVAVFGYLGGLIFT-TNSGMYWLQLM 464
               S  A ++ +  A+ + F     Q   WV  ++ + G    L FT  N  +    ++
Sbjct: 310 AAFSSCLAGLKVLIAAVAEEFKQTNTQAVVWVCLLMLILGLFSALSFTPLNLNINGEPVL 369

Query: 465 DKYAANWSVLIIAIGECILIAWIYGAEKFC-----GDIQRMIGRQSKLWVYLWSAMWRII 519
           D       +  IA G+ I+++ I GA  FC       I+ ++G +++ W       WRI 
Sbjct: 370 D------VIDRIAGGDVIIVSGIMGAALFCWFIPPQTIRSVLGTENRWW------EWRIY 417

Query: 520 TPAALVFILVFNWI 533
                + +LV  W+
Sbjct: 418 LIGRFLPVLVVAWL 431


>UniRef50_A3VN81 Cluster: Sodium-dependent transporter family
           protein; n=1; Parvularcula bermudensis HTCC2503|Rep:
           Sodium-dependent transporter family protein -
           Parvularcula bermudensis HTCC2503
          Length = 502

 Score = 82.2 bits (194), Expect = 4e-14
 Identities = 80/288 (27%), Positives = 130/288 (45%), Gaps = 12/288 (4%)

Query: 187 VSHNITALAKTALRRPPAEEYFTNQVLG-LSSGIEETGEIRLGMAMCLLAAWVIVFLCLC 245
           +     A    AL  P  E     ++ G L   + + G + +  A+ + A   I+   + 
Sbjct: 131 IGGRFVAEGPVALTAPAFEGQSDEEIGGILPKLLSQPGRMIVLHALFMAATVFILSRGVK 190

Query: 246 KGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAV 305
            G++++  V+    +F  ++L +  F  VT   A+  + F  TPDFSQL  + +   A  
Sbjct: 191 SGIEAAANVMM--PIFFVLLLGLTTFSLVT-GEAMQALTFLFTPDFSQLTGSTLLR-AVG 246

Query: 306 QIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELN 365
           Q FF+LS     ++T  +Y     +    S IVA ++ A +  AGL +F ++ F +  L+
Sbjct: 247 QAFFSLSLGAAMMLTYGTYLSRETDIKSSSQIVATADTAVALIAGLALFPIV-FASPVLS 305

Query: 366 VSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMET-VTTAIL 424
             V    D G GL F+  P     +P   L+ + FFVM L   L S  AL+ET V+ A  
Sbjct: 306 ADVMGDNDPGLGLLFVTVPRAFHLMPFGSLFGLAFFVMALFAALTSAIALLETSVSWADG 365

Query: 425 D-RFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANW 471
           D   P  ++ +  V+  +     LGGL F    G    Q+    AA +
Sbjct: 366 DYDVPPAQKARRRVIGAIC----LGGLAFLIGIGHALSQVPQTVAATF 409



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 28/118 (23%), Positives = 56/118 (47%), Gaps = 12/118 (10%)

Query: 28  NWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFG 87
           NW+GR  F            N+ RFPY+  ++GGGAF+  +   ++  G+P++  E   G
Sbjct: 12  NWSGRAAFILAAVGSAVGLGNLVRFPYVAGDSGGGAFIFVYLATILFIGVPVLIAEFMIG 71

Query: 88  QYAALGPVAVYNKFC---------PLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTV 136
           +      +A  ++            +F  LG   ++ S +++ YY+++  W + ++ V
Sbjct: 72  RRGGGSAIAAVSRLARTEGRTRAWVIFPILG---ILASFLIVSYYSVLAGWILHFIQV 126


>UniRef50_Q8MSR0 Cluster: Transporter; n=3; Sophophora|Rep:
           Transporter - Drosophila melanogaster (Fruit fly)
          Length = 1331

 Score = 81.8 bits (193), Expect = 5e-14
 Identities = 79/287 (27%), Positives = 124/287 (43%), Gaps = 36/287 (12%)

Query: 48  NVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRG 107
           N+ RF  L  N GG  FL+ F ++ VI G+PL+++++  G     GPV+++ K  P+  G
Sbjct: 516 NMCRFAVLTINFGGN-FLLQFLLLSVIFGIPLLWLQMCLGAKIRAGPVSMW-KISPICAG 573

Query: 108 LGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQ-LPWQNCKAEWSTKHCYSYEEAD 166
           +G  +V+    + LY  + +AW + Y+   F +       WQ    E +  + Y      
Sbjct: 574 VGIALVMQQCFLALYSTVSLAWILVYLRDVFPTAARSGYRWQ----EMAFPYRY------ 623

Query: 167 ECEAQNGTYYLRQCFNQSYSVSHNITALAKTALRRPPAEEYFTNQVLGLSSGIEETGEIR 226
             +A N T  L Q   + +    N+  L +  L   P            +SGI      R
Sbjct: 624 --DASNATGNLTQTVAEYF----NVVVLQRLHLANHPD-----------ASGIRFHVNDR 666

Query: 227 LGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILF--FRGVTLPGAITGIL 284
             +A  L   W  VFL LCKG++S GK+ Y     P V L ++   F  V  P  I  I 
Sbjct: 667 -QLAFYLALIWAAVFLILCKGLKSLGKLAYIIYTLPLVALAVVTAKFVYVVDPSRIQNI- 724

Query: 285 FYLTPDFSQ-LANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNN 330
            +   DF   L N+  W  A  + F         +I ++S +  + N
Sbjct: 725 -FAASDFDDFLVNSNSWTAATQETFLTWGLLGASVIAITSRSHTNAN 770


>UniRef50_Q8RHM5 Cluster: Sodium-dependent tyrosine transporter;
           n=7; Bacteria|Rep: Sodium-dependent tyrosine transporter
           - Fusobacterium nucleatum subsp. nucleatum
          Length = 438

 Score = 81.4 bits (192), Expect = 7e-14
 Identities = 65/245 (26%), Positives = 104/245 (42%), Gaps = 10/245 (4%)

Query: 234 LAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQ 293
           +A  V+  L L  G +S  K         +V+  IL  R   LPGAI G  +   PD+S 
Sbjct: 151 IAVIVLTLLTLFAGAKSIEKTNKIMMPAFFVLFFILAVRVAFLPGAIEGYKYLFVPDWSY 210

Query: 294 LANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVI 353
           L+N + W +A  Q FF+LS    G+I   +Y     +    +L   V +   +  A  V+
Sbjct: 211 LSNVETWINAMGQAFFSLSITGSGMIVCGAYLDKKEDIINGALQTGVFDTIAAMIAAFVV 270

Query: 354 FSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQF 413
                      + +       G  L F+  PEV  ++P   L +ILFFV ++   + S  
Sbjct: 271 IPA--------SFAFGYPASAGPSLMFMTIPEVFKQMPFGQLLAILFFVSVVFAAISSLQ 322

Query: 414 ALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSV 473
            + E V  +I  RF   R  K  +V +  +   +G  I   N    W+ ++  Y   +  
Sbjct: 323 NMFEVVGESIQTRFKMTR--KSVIVLLGIIALVIGIFIEPENKVGPWMDVVTIYIIPFGA 380

Query: 474 LIIAI 478
           ++ AI
Sbjct: 381 VLGAI 385



 Score = 38.7 bits (86), Expect = 0.47
 Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 6/90 (6%)

Query: 48  NVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYN-KFCPLFR 106
           N+W FPY     GG  FL+ + + + +     +  E   G+ A  G +  Y   +  + +
Sbjct: 27  NIWAFPYRVGKYGGAVFLLIYFMFIALFSYVGLSAEYLIGRRAETGTLGSYEYAWKDVGK 86

Query: 107 G-LGYGMVIV----SSIVMLYYNLIIAWTI 131
           G LGYG+  +    S  + + Y +I AW +
Sbjct: 87  GKLGYGLAYIPLLGSMSIAIGYAVIAAWVL 116


>UniRef50_A6PRZ0 Cluster: Transporter; n=2; Bacteria|Rep:
           Transporter - Victivallis vadensis ATCC BAA-548
          Length = 497

 Score = 81.4 bits (192), Expect = 7e-14
 Identities = 64/227 (28%), Positives = 104/227 (45%), Gaps = 15/227 (6%)

Query: 211 QVLGLSSGIEETGEIRLG-MAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVIL 269
           +++G  +G   +    +G M + +L   V  +L L KGV+   K++    LF  ++L+ L
Sbjct: 172 EIIGYFNGFLASPGRNVGYMLLTVLIGSVTCYLGLQKGVERITKLM-MAGLF--LLLLGL 228

Query: 270 FFRGVTLPGAITGILFYLTPDFSQLANAQVWG---DAAVQIFFALSPAWGGLITLSSYNK 326
             R  TLPGA  G+ FYL P    L    ++     A  Q FF LS   G +    SY  
Sbjct: 229 CIRSCTLPGASAGLSFYLKPSLEPLETVGLFNIIVAALGQAFFTLSLGVGSIAIFGSYID 288

Query: 327 FSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEV 386
             ++   +SL++   +   +  AG++IF          +  VD     G GL FI  P V
Sbjct: 289 RDHSLAKESLVIIALDTIVAILAGVIIFPAC------FSYGVD--AGSGPGLVFISLPNV 340

Query: 387 VTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQK 433
              +P    W +LFF+ L +  L +  A+ E +   ++D +   R+K
Sbjct: 341 FNHMPGGRWWGVLFFLFLSSAALTTVIAVFENLIAFMIDEWRLSRRK 387



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 31/91 (34%), Positives = 47/91 (51%), Gaps = 6/91 (6%)

Query: 48  NVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCP---L 104
           N+WRFP++   NGG  F++ + V L + G P+M MELS G+ +       Y K  P    
Sbjct: 66  NIWRFPFVTGQNGGALFVLIYLVFLFMLGFPVMVMELSLGRASRRNLYGAY-KTLPKGSS 124

Query: 105 FRGLGYGMVIV--SSIVMLYYNLIIAWTIFY 133
           F+    G V    S+ +M++Y  +  W I Y
Sbjct: 125 FKWHWPGAVFFTGSAFLMIFYTTVTGWMIAY 155


>UniRef50_A0RQG4 Cluster: Sodium-and chloride-dependent transporter;
           n=19; Campylobacter|Rep: Sodium-and chloride-dependent
           transporter - Campylobacter fetus subsp. fetus (strain
           82-40)
          Length = 458

 Score = 81.4 bits (192), Expect = 7e-14
 Identities = 78/327 (23%), Positives = 145/327 (44%), Gaps = 31/327 (9%)

Query: 227 LGMAMCLLAAWVIVFLCLCKGVQSSGK---VVYFTALFPYVVLVILFFRGVTLPGAITGI 283
           + + +C    +++VF  + KG++S  +   +    +LF  +VL++L+    +  G ++ +
Sbjct: 139 ISVFICFTLVFLLVFYVVSKGIKSGIERLNIWMMPSLFGLLVLLLLYSIFQS-GGFVSAV 197

Query: 284 LFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNI 343
            F   PDFS+L N  +   A    FF++S   G + T ++      N    +  +   NI
Sbjct: 198 QFLFIPDFSKLLNPSIILQALGLAFFSMSMGVGTVATYAASLPDGTNLIKSTFSIVSINI 257

Query: 344 ATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRL-PISPLWSILFFV 402
                 GLV+FS I        +   +   +GAGL F+    +  ++  +  + +I FF+
Sbjct: 258 LIGIMMGLVVFSFI-------PIQDGQPASEGAGLIFVSLTSLFAQMGVVGNVLAIAFFI 310

Query: 403 MLLTLGLDSQFALMETVTTAILDRFPNFRQKK----GWVVFIV---AVFGYLGGL----- 450
            LL  G+ S  +++E  T  ++++F   R+      G +V+I+    +  Y G       
Sbjct: 311 SLLFAGVTSAVSMIEPFTLYLINKFNISRKMSITFIGVLVYILGICCILSYYGDTSASFS 370

Query: 451 ----IFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSK 506
               IF T   + +  ++D   +N  + I A+   I + WI    K  G      G  SK
Sbjct: 371 LPKEIFATQKPVPFFDMLDFMTSNVLMPIGALTFSIFVGWIL---KRDGLYILFSGFISK 427

Query: 507 LWVYLWSAMWRIITPAALVFILVFNWI 533
            W  +W    R + P A++ I V+  I
Sbjct: 428 TWFEIWYFALRYVAPIAIIAIGVYQLI 454



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 25/97 (25%), Positives = 50/97 (51%), Gaps = 3/97 (3%)

Query: 48  NVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCPLFR- 106
           N W+FP +  NNGG AF++ + ++ +   + +   EL+ G+      V    K  P  + 
Sbjct: 23  NAWKFPTMVGNNGGSAFILLYVLLTLGIAVVVFLAELAIGKLGETDIVGSLYKLAPKHKK 82

Query: 107 --GLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSI 141
              L    +I + ++  +Y ++I W + Y+ +SFS++
Sbjct: 83  QWSLAGFFMITAVLIASFYMIVIGWILKYIFMSFSTL 119


>UniRef50_Q9HPQ2 Cluster: Daunorubicin resistance ABC transporter
           ATP-binding protein; n=2; Halobacteriaceae|Rep:
           Daunorubicin resistance ABC transporter ATP-binding
           protein - Halobacterium salinarium (Halobacterium
           halobium)
          Length = 447

 Score = 81.4 bits (192), Expect = 7e-14
 Identities = 67/246 (27%), Positives = 110/246 (44%), Gaps = 14/246 (5%)

Query: 247 GVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLAN--AQVWGDAA 304
           G++ + K++  + L   V+LV L     TL G      FYL+PDF  +A+    +   A 
Sbjct: 160 GIEKATKLMVPSIL---VMLVGLAVYASTLNGVGAAYEFYLSPDFGFIADNIGSIVPYAV 216

Query: 305 VQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHEL 364
            Q FF+LS   G +IT +SY    ++ + D  ++ V N +    AGLV   VI  L  + 
Sbjct: 217 SQAFFSLSLGMGAMITYASYLGDDDSLFADGGLIVVLNTSVGLLAGLV---VIPLLFVQF 273

Query: 365 NVSVDRVVDQGAGLAFIVYPEVVTRLPIS-PLWSILFFVMLLTLGLDSQFALMETVTTAI 423
               D     GAG  FI   +    L ++  +  +LFF ++L   L S  +L+E VT  +
Sbjct: 274 GTVPDAAAGGGAGALFISVAQAFATLGVAGRVLGVLFFGVVLVAALSSAISLLEVVTAYV 333

Query: 424 LDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECIL 483
           +D   N+   +    F      +  G +   N+   WL   D  A    + +  +   + 
Sbjct: 334 VD---NYGYSRPATAFSFGGVLFALGTLSAWNTA--WLDWFDSLAYGVLLPLSVLLGVVF 388

Query: 484 IAWIYG 489
           + W+YG
Sbjct: 389 VGWVYG 394



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 30/123 (24%), Positives = 56/123 (45%), Gaps = 1/123 (0%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           ER  W  R  F            N+W+FP+     GG AF++ + V  ++ GLP +  E 
Sbjct: 3   ERETWASRLGFILAAVGSAVGLGNIWQFPFKTATEGGAAFVVVYLVAALLLGLPAILGEF 62

Query: 85  SFGQYAALGPVAVYNKF-CPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFY 143
             G+ A L  V  +++   P +  +G   ++    ++ YY+++  W   Y+  S +  ++
Sbjct: 63  VIGRRANLNAVEAFDRLDHPAWTIVGAMGLLTGLWILSYYSVVGGWVTRYLLGSATGAYF 122

Query: 144 QLP 146
             P
Sbjct: 123 AAP 125


>UniRef50_Q5QUN5 Cluster: Na+-dependent transporter of the SNF
           family; n=7; Alteromonadales|Rep: Na+-dependent
           transporter of the SNF family - Idiomarina loihiensis
          Length = 439

 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 73/228 (32%), Positives = 111/228 (48%), Gaps = 10/228 (4%)

Query: 230 AMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTP 289
           A+ LLA   +VF  + KG++   K +  T +   V+LV L    +TLPGA  G+  YL P
Sbjct: 145 AVFLLATAYVVFQGVEKGIERWSKRLMPTLV---VLLVALIAYMLTLPGADEGLKKYLVP 201

Query: 290 DFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFA 349
           DFS + +  +   A  Q FF+LS   GG++   SY K   N    SL VA  +   +F A
Sbjct: 202 DFSLMTDTSILVAAMGQAFFSLSIGLGGMMIYGSYLKPGANLGRLSLSVAALDTFIAFLA 261

Query: 350 GLVIFSVIGFLAHELNVSV---DRVVDQGAGLAFIVYPEVVTRLPIS-PLWSILFFVMLL 405
           GL+I   + +    L V+V    +++ +G  L F V PE+   + I+ P  +  FF++L 
Sbjct: 262 GLLIIPAL-YAGIHLGVNVGEGSKLIGEGQ-LIFAVLPELFNSMGIAGPFVAFAFFMLLS 319

Query: 406 TLGLDSQFALMET-VTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIF 452
              L S  A  E  V+  I +R           + ++A+F  L  L F
Sbjct: 320 IAALTSTIAQAEVPVSYCIEERKLKRPVATALSLSVIAMFSLLLILFF 367



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 29/113 (25%), Positives = 54/113 (47%), Gaps = 5/113 (4%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           R ++  R  F            N+W FP    N+GGGAFL+ +  ++ I  +P ++ E+ 
Sbjct: 2   RDSFHSRIGFILAAAGSAVGLGNIWGFPTQVANHGGGAFLLVYLCVIFILAIPALYSEML 61

Query: 86  FGQYAALGPVAVYNKFC-----PLFRGLGYGMVIVSSIVMLYYNLIIAWTIFY 133
            G  A   PV    +       P+ R +GY  V+ S +++ +Y+++  W + +
Sbjct: 62  IGHSAQANPVRSLTQLSEGRARPIGRLMGYLNVLGSCLMLSFYHVVAGWMLVH 114


>UniRef50_Q7NPX3 Cluster: Transporter; n=5; Proteobacteria|Rep:
           Transporter - Chromobacterium violaceum
          Length = 437

 Score = 79.4 bits (187), Expect = 3e-13
 Identities = 77/250 (30%), Positives = 113/250 (45%), Gaps = 21/250 (8%)

Query: 246 KGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAV 305
           KG++ +GK++    LF  ++++ L  R VTLPGA+ G+     PDFS+L    +  +A  
Sbjct: 163 KGIERAGKLL-MPLLF--LLMLALIVRAVTLPGAMAGVAALFRPDFSRLTPGMLV-EALG 218

Query: 306 QIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELN 365
              F+LS   G ++   SY          +L V      TS  AGL+IF  I   A  LN
Sbjct: 219 LACFSLSVGAGCMLAYGSYLGPGTRLGNSALWVTGLTALTSVLAGLMIFPAI--YAFGLN 276

Query: 366 VSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILD 425
                    G GL ++V P V   LP   L++  FF +LL   L S  +L+E V    +D
Sbjct: 277 PQA------GPGLTYMVMPVVFNHLPYGQLFATAFFALLLMAALTSAVSLLEVVAILPID 330

Query: 426 RFPNFRQKKGWVV----FIVAVFGYL--GGLIFTTNSGMYWLQLMDKYAANWSVLIIAIG 479
            F   R++    V    F+  V   L  G L      G    +LMD  A+N  + +  IG
Sbjct: 331 EFGVGRRQATLAVTALAFLAGVPAALSFGPLADCKLFGRTAFELMDYAASNVLLPLGCIG 390

Query: 480 ECIL---IAW 486
             +    +AW
Sbjct: 391 TALFAGRVAW 400



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 34/110 (30%), Positives = 57/110 (51%), Gaps = 1/110 (0%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           R  W  R  F            ++W+FPY+   NGGGAFL+ +       GL L+  EL+
Sbjct: 3   RTQWGSRLGFILASAGATVGLGSIWKFPYVTAMNGGGAFLLVYLAFTFTLGLALLQAELA 62

Query: 86  FGQYAALGPVAVYNKF-CPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYM 134
            G+ A  G V  +++   P ++ LGYG V+   ++  +Y+++  WT+ Y+
Sbjct: 63  LGRAAGCGAVGAFSRLGSPRWKLLGYGGVLCCFLIFSFYSVVGGWTLGYL 112


>UniRef50_Q4LEH9 Cluster: Sodium-dependent transporter; n=1;
           uncultured crenarchaeote 45-H-12|Rep: Sodium-dependent
           transporter - uncultured crenarchaeote 45-H-12
          Length = 438

 Score = 79.4 bits (187), Expect = 3e-13
 Identities = 59/274 (21%), Positives = 133/274 (48%), Gaps = 19/274 (6%)

Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322
           + +L+ L   G+++     G+ +Y  PD ++L +  VW  A  Q FF+LS   G L+T +
Sbjct: 171 FAMLIPLALIGLSMDRDGLGLRYYTQPDSNRLLDPHVWSSAIGQAFFSLSIGLGVLVTYA 230

Query: 323 SY-NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFI 381
           SY  +   +  + SLI+  S +  +F +GL++F+++   A+ L          G  L FI
Sbjct: 231 SYVREQKQSVVVTSLIIVGSVLVVAFLSGLMVFTMV--FANGLGDV------HGTALVFI 282

Query: 382 VYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIV 441
             P+++  +    L  I FF++L   G+ S  ++++   +A+ D F   + +   V+ ++
Sbjct: 283 AMPKIIAGMEYGYLLGITFFLLLFIAGITSSISMLQIPVSALEDTFKFSKARATMVITML 342

Query: 442 AV-FGYLGGLIFT-TNSGMYWLQLMDKYAANWSVLIIAIGECIL---IAWIYGAEKFCGD 496
           ++  G    L ++  +  +  + ++D +   +  + +A+   ++   +AW    +    +
Sbjct: 343 SLALGIPSALSYSPVHLSISSMPVLDAFDWIFGTIALAVSATLMAVAVAWFMSRD----E 398

Query: 497 IQRMIGRQSKLWV-YLWSAMWRIITPAALVFILV 529
           +   +   S++ +      + RI+ PA ++  L+
Sbjct: 399 MMEQVNMNSRIRIPSRMLDLVRILLPAMIIATLM 432



 Score = 70.9 bits (166), Expect = 9e-11
 Identities = 32/118 (27%), Positives = 56/118 (47%)

Query: 20  EEIEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPL 79
           E +  ER  W     F            ++WRFPY+   NGG +FL+ + ++L   GL  
Sbjct: 2   ERVGRERETWGSYTGFILTTIGSAVGIGSIWRFPYMVSTNGGASFLLVYIIVLFTFGLAF 61

Query: 80  MFMELSFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVS 137
           M +E + G       V+  +     FR +G  M+ V+  ++ YY +++ W + Y+ +S
Sbjct: 62  MVLEFALGMRYRTSIVSALSMIRHRFRFIGLFMIGVTVAILSYYMVVLGWILAYLVMS 119


>UniRef50_Q6MBR5 Cluster: Transporter; n=1; Candidatus
           Protochlamydia amoebophila UWE25|Rep: Transporter -
           Protochlamydia amoebophila (strain UWE25)
          Length = 466

 Score = 78.6 bits (185), Expect = 5e-13
 Identities = 83/308 (26%), Positives = 126/308 (40%), Gaps = 26/308 (8%)

Query: 237 WVIVFLCLCKGVQSSG---KVVYFTALFPYVVLVILFFR---GVTLPGAITGILFYLTPD 290
           W  +F  L   V   G    + Y++      +L+IL        TLPG   G+ F   PD
Sbjct: 149 WHFLFTALTAAVVYRGIRQGIEYWSRFMTIGLLIILLSMCAYAFTLPGFREGVNFIFYPD 208

Query: 291 FSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAG 350
            S+   +    DA    FF LS   G ++T  SY +  +N    ++I+ V  +  S  AG
Sbjct: 209 LSRFKPSAAI-DALGLSFFTLSLGQGIMLTYGSYMRRGDNIPKTAVIIGVMIVLISLLAG 267

Query: 351 LVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLD 410
           L+IF +I         S     + G GL F   P +  +LP +   S  FFV+ +   L 
Sbjct: 268 LMIFPII--------FSFGFAPEAGPGLVFKTLPVLFAQLPGALFISTAFFVLFVFTALT 319

Query: 411 SQFALMETVTTAILDRFPNFRQKKGWVVFIVA-VFGYLGGL-----IFTTNSGMY---WL 461
           S  AL+E VT    D     RQK   +V I   +FG    L     +F     +Y   + 
Sbjct: 320 SAVALIEVVTANFTDLLGWSRQKAVLIVSISCFIFGIPSALSNTNTLFANWPAIYGKTFF 379

Query: 462 QLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITP 521
           Q +D     W + I  +   I   W+   +K     +   G   +   + W    R + P
Sbjct: 380 QTIDDLVTLWFLPIGGLLVSIFTGWV--LDKELAKEEFSSGTTMRWLWHPWIFFIRWVAP 437

Query: 522 AALVFILV 529
            A+VFI++
Sbjct: 438 IAIVFIIL 445



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 29/124 (23%), Positives = 59/124 (47%), Gaps = 3/124 (2%)

Query: 22  IEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMF 81
           ++ +R +W+    F             +W+FPY+   NGGG F+  + +     G+P+  
Sbjct: 1   MQKQREHWSSHLGFILAAAGSAIGLGTLWKFPYVTGENGGGLFVFIYILCTFFIGVPVFI 60

Query: 82  MELSFGQYAALGPVAVYNKFC---PLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSF 138
            EL  G+ A  G V ++         ++ +G+  V  S ++M +Y+++  W + Y+ +S 
Sbjct: 61  AELILGRKAQRGAVGIFASLANNSAAWKTVGWLGVASSFLIMSFYSILAGWGLNYIFMSL 120

Query: 139 SSIF 142
           S  +
Sbjct: 121 SQFY 124


>UniRef50_Q3INN0 Cluster: Transporter 55; n=1; Natronomonas
           pharaonis DSM 2160|Rep: Transporter 55 - Natronomonas
           pharaonis (strain DSM 2160 / ATCC 35678)
          Length = 442

 Score = 77.8 bits (183), Expect = 8e-13
 Identities = 72/298 (24%), Positives = 135/298 (45%), Gaps = 30/298 (10%)

Query: 239 IVFLCLCKGVQSSGKVVYFTALFPYVVLVI--LFFRGVTLPGAITGILFYLTPDFSQLAN 296
           IV L + +G++ + K     A+ P + L++  L    +TL G + G  +YL+PDF+ LA 
Sbjct: 151 IVMLGIKRGIELAVK-----AMVPAIALLLAGLAVYALTLDGVVDGYRYYLSPDFATLAA 205

Query: 297 --AQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIF 354
               +   A  Q  F LS   G +IT +SY     +  +DS  +A+ +   +F +GL++F
Sbjct: 206 EWTTILPAAVGQALFTLSLGMGVMITYASYVGEDQSLLVDSGSIALLDTVIAFLSGLILF 265

Query: 355 SVIGFLAHELNVSVDRVV-DQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQF 413
            ++         ++D    D GAG  FI        +P+  +  ++FFV L    L S  
Sbjct: 266 PIL--------FTIDATPGDGGAGEFFIGVGGAFADIPLGTIVGVVFFVTLAVAALSSAI 317

Query: 414 ALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSV 473
           +++E + +  +D F   R+      F V V  ++ G+    + G +  ++ D+       
Sbjct: 318 SILEVIVSYFIDEFGFDRRV---ATFGVGVIVFVAGIPAALDMGTF--EVYDQVTGE--- 369

Query: 474 LIIAIGECIL---IAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFIL 528
           L++ +G  +L   +AW+   E     ++   G    ++ +LW     +     L  +L
Sbjct: 370 LLLPLGMFLLVLFVAWVVPEESLDELLKGRSGSNLDVF-WLWWVRTVVTVAVGLTLVL 426



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 31/120 (25%), Positives = 57/120 (47%), Gaps = 1/120 (0%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           ER  W  R  F            N+WRFP+    NGG AFLI +   +++ G+P + +E 
Sbjct: 2   ERETWATRIGFILAAVGSAVGLGNIWRFPFQVGQNGGSAFLIMYLACVLLIGIPAILVEF 61

Query: 85  SFGQYAALGPVAVYNKF-CPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFY 143
             G+ +   P+  ++      FR +G   V+   +++ YY ++  W + Y+  S +  ++
Sbjct: 62  VIGRRSQRNPIGAFHALGKSRFRAIGAVCVVTGFVILSYYTVVAGWVLRYIGGSATGAYF 121


>UniRef50_A4BUI1 Cluster: Probable sodium-dependent transporter;
           n=1; Nitrococcus mobilis Nb-231|Rep: Probable
           sodium-dependent transporter - Nitrococcus mobilis
           Nb-231
          Length = 433

 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 37/123 (30%), Positives = 62/123 (50%), Gaps = 2/123 (1%)

Query: 22  IEPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMF 81
           +E  RG+W+ R  F            N+W+FPY+   NGG AF+  + V +    LP++ 
Sbjct: 3   VESVRGSWSNRLGFVLAAAGSAVGLGNIWKFPYMAGKNGGAAFIFVYIVSVFAICLPIVV 62

Query: 82  MELSFGQYAALGPVAVYNKFCP-LFRGLGYGMVIVSSIVML-YYNLIIAWTIFYMTVSFS 139
            EL  G+ +   PV  +    P  F  LG  + ++S  ++L +Y ++  WT+ +M +S S
Sbjct: 63  AELMLGRTSRRNPVGAFQSLRPRSFWVLGGWLGVLSGFLILSFYGVVAGWTLDFMLLSAS 122

Query: 140 SIF 142
             F
Sbjct: 123 GSF 125



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 78/302 (25%), Positives = 135/302 (44%), Gaps = 27/302 (8%)

Query: 230 AMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRG--VTLPGAITGILFYL 287
           A+ ++A  +IV   +  G++   ++     L P ++L+++   G  +TL GA     F L
Sbjct: 152 ALFMVATIIIVAGGIASGIERGSRI-----LLPALLLMLIGLVGFSLTLSGAGDAAAFLL 206

Query: 288 TPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSF 347
           TP + + +   +   A  Q FF+LS   G +IT  SY     +    +  VA+++ A + 
Sbjct: 207 TPRWEEFSGESLLA-ALGQAFFSLSLGMGVMITYGSYLGSGESLSRSAFYVALTDTAVAL 265

Query: 348 FAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTL 407
            AG  IF ++     E           G GL F   P    +LP + L +  FF++L   
Sbjct: 266 LAGAAIFPIVFTFGFEPAA--------GPGLTFQTLPVAFAQLPWAGLLAFTFFLLLSLA 317

Query: 408 GLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQLMDKY 467
            L S  +L+E V    +D +   R    W  F   V  +L G+    +S   W++ +D  
Sbjct: 318 ALTSSISLLEVVVAYFIDEWRWRRVTAAW--FCGGV-TFLAGVPCAVDSA--WIERLDAL 372

Query: 468 AANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFI 527
            +N+    + IG  +LIA   G      + +  +G  + +    W  M R ++PAA+V I
Sbjct: 373 TSNY---FLPIGG-LLIAAFAGWVLVPAEQESELG--TNVLTRTWRFMIRWVSPAAVVAI 426

Query: 528 LV 529
            +
Sbjct: 427 FL 428


>UniRef50_Q1N1Z9 Cluster: Na+-dependent transporter of the SNF
           family protein; n=1; Oceanobacter sp. RED65|Rep:
           Na+-dependent transporter of the SNF family protein -
           Oceanobacter sp. RED65
          Length = 355

 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 63/197 (31%), Positives = 100/197 (50%), Gaps = 10/197 (5%)

Query: 234 LAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQ 293
           L A VIV L +  G++   K++  T L   ++L+I+    +TL GA  GI +Y T DFSQ
Sbjct: 144 LTACVIV-LGVKNGIERLSKILMPTLL---LLLIIMIIWVLTLDGASKGISWYFTSDFSQ 199

Query: 294 LANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVI 353
           L + ++ G A  Q FF+LS    G++T  +Y K S         V + + + +F AGL+I
Sbjct: 200 L-SPELLGRALGQAFFSLSIGVTGMMTYGAYLKRSRGLPKTVASVTLLDTSVAFLAGLLI 258

Query: 354 FSVIGFLAHELNVSVDRVVDQGAG---LAFIVYPEVVTRLPISPLW-SILFFVMLLTLGL 409
              +   A    ++V     Q  G   L F + P +   L ++ L  SILFFV+LL   +
Sbjct: 259 LPALS-AAQAQGITVFNGAGQLIGSDKLVFDILPALFANLGVTGLLISILFFVLLLIAAI 317

Query: 410 DSQFALMETVTTAILDR 426
            S  ++ME     + ++
Sbjct: 318 TSSISMMEPPVNTLQEK 334



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 26/108 (24%), Positives = 52/108 (48%), Gaps = 6/108 (5%)

Query: 28  NWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFG 87
           ++T +  F            N+W FP    NNGGG FL+ +  M+V+ G P++  E++ G
Sbjct: 5   HFTSKLGFIAAAAGSAVGLGNIWGFPTEAANNGGGTFLLIYFAMVVLVGYPMLLAEVTIG 64

Query: 88  QYAALGPVAVYNKFCP------LFRGLGYGMVIVSSIVMLYYNLIIAW 129
             A   P+   ++         +  G+G+   +   +++ +Y+++ AW
Sbjct: 65  NLAQANPIDALSRLTQKAKSRIVLAGIGWAGTLTILLILSFYSVVGAW 112


>UniRef50_Q6MLR2 Cluster: Sodium-dependent serine transporter; n=1;
           Bdellovibrio bacteriovorus|Rep: Sodium-dependent serine
           transporter - Bdellovibrio bacteriovorus
          Length = 455

 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 37/122 (30%), Positives = 62/122 (50%), Gaps = 4/122 (3%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           +RG+W  R+ F            N+WRFPY+   NGGGAF++ + ++ +  G PL+  EL
Sbjct: 4   KRGSWKTRYGFYLLAIGSACGLGNLWRFPYVVGENGGGAFILLYGLLALAIGAPLLIAEL 63

Query: 85  SFGQYAALGPVAVYNKFCPL----FRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSS 140
             G+      +    +        FR +G   V+VS +V+ YY++I  W + ++T    S
Sbjct: 64  MLGKGTRRSVIVATQQMSAKTGVNFRWVGRLAVMVSIVVLSYYSVISGWVLHFLTQFLVS 123

Query: 141 IF 142
           +F
Sbjct: 124 LF 125



 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 67/261 (25%), Positives = 116/261 (44%), Gaps = 21/261 (8%)

Query: 238 VIVFLCLCKGVQSSGK--VVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLA 295
           +I  + + KGVQ   +  + Y   LF  V+++IL  R  +LP     + F   PDFS+L+
Sbjct: 156 LITVVVVVKGVQQGLERWIGYTMPLFA-VLVIILVMRSFSLPSTPEVLRFLFYPDFSKLS 214

Query: 296 NAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFS 355
              +   A   +FF LS  +G ++T  SY +  ++       V + +   S  A ++IF 
Sbjct: 215 WDSI-NHALGHVFFTLSVGFGTMVTFGSYMREEDHVPTAGFRVTIVDTVISLVAVVMIFP 273

Query: 356 VIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFAL 415
           V  F A  + ++          L F V P+ +  +    L+ + FF  L    L++   L
Sbjct: 274 V-AFQASNVPLT-------DPALMFEVLPKYLLGIRGGTLFGLAFFACLYMAALNASIGL 325

Query: 416 METVTTAILDRFPNFRQKK-----GWVVFIVAVFGYLGGLIF--TTNSGMYWLQLMDKYA 468
           +E V +  +D      + K     G +  ++ V   L   IF      G   ++ +D   
Sbjct: 326 LEVVVSNWVDAKKEMERGKATWYSGAIALMLTVLPALSSSIFKDIRVGGRSLIENLDSLL 385

Query: 469 ANWSVLIIAIGECILIAWIYG 489
            NW + ++A+G  ILIA+  G
Sbjct: 386 INWLLPLVALG--ILIAFNRG 404


>UniRef50_O25240 Cluster: Sodium-and chloride-dependent transporter;
           n=4; Helicobacter|Rep: Sodium-and chloride-dependent
           transporter - Helicobacter pylori (Campylobacter pylori)
          Length = 442

 Score = 75.8 bits (178), Expect = 3e-12
 Identities = 66/224 (29%), Positives = 109/224 (48%), Gaps = 16/224 (7%)

Query: 227 LGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFY 286
           +G + CLL     V   + +G++    VV    LF  V+ + L    +TL      + F 
Sbjct: 142 IGFSACLLPTIWFVSRGIEEGIEKLN-VVLMPLLF--VIFIGLLIYAMTLESMPKALHFL 198

Query: 287 LTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATS 346
              +  ++ + +V  DA  Q+FF+LS   G +IT S++     N +  SL + +  I  S
Sbjct: 199 FNFEIQKI-DFKVVMDALGQMFFSLSLGVGTIITYSAFTPKKENLFKSSLFIVLPGILIS 257

Query: 347 FFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPIS-PLWSILFFVMLL 405
             AG++IF+ + F  H      D  V QG GL FI  P    ++ +S  + S+ FF+ L+
Sbjct: 258 LIAGVMIFTFV-FEYH-----AD--VSQGPGLVFISLPLTFAKMGMSGQIVSLFFFMALV 309

Query: 406 TLGLDSQFALMETVTTAILDRFPNFR--QKKGWVVFIVAVFGYL 447
             G+ S  +L+E +   +++RF NF   Q   W+  +V V G L
Sbjct: 310 FAGITSTVSLIEPLALYLINRF-NFSRLQASLWIGVVVYVLGVL 352



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 21/92 (22%), Positives = 49/92 (53%), Gaps = 3/92 (3%)

Query: 48  NVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCP---L 104
           ++WRFPY+  +NGG AF++ + V+ +  G+ ++ +E+  G       V+ Y    P    
Sbjct: 22  HIWRFPYMVGHNGGSAFVLLYLVLTLSLGIAMLLVEMLIGNLGKKDVVSNYQILDPKRKK 81

Query: 105 FRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTV 136
           +       ++   +++ +Y +++ W ++Y+ V
Sbjct: 82  YYPFTSFFILGGPLILSFYAVVLGWVLYYLFV 113


>UniRef50_A6VX44 Cluster: Transporter; n=12;
           Gammaproteobacteria|Rep: Transporter - Marinomonas sp.
           MWYL1
          Length = 466

 Score = 75.8 bits (178), Expect = 3e-12
 Identities = 72/309 (23%), Positives = 129/309 (41%), Gaps = 27/309 (8%)

Query: 234 LAAWVIVFLCLCKGVQ----SSGKVVYFTALFPYVVLVILFFRGVTLPGA--ITGILFYL 287
           L  W+ V L L  G+       G       L P +++++L   G  +     + G+ F  
Sbjct: 164 LTIWMTVVLGLTMGIVLRGLHGGLEKAINLLMPGLLILLLILVGYAMTSGHFMEGVSFLF 223

Query: 288 TPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSF 347
             DFS++        A    FF LS A G ++T  SY   + +    ++I+A+ +   + 
Sbjct: 224 KADFSKMTGTGFLV-ALGHAFFTLSLASGAIMTYGSYLPENVSIGKTTMIIAIMDTVVAL 282

Query: 348 FAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTL 407
            AGL IF ++   A+ L          G GL F+  P    ++P    +  LFF++L   
Sbjct: 283 AAGLAIFPLV--FANGLEPGA------GPGLIFVTLPIAFGQMPFGSTFGTLFFLLLAVA 334

Query: 408 GLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYW------- 460
            L S  +++E   + + ++F   R K   +   +   G L G++ + N G  W       
Sbjct: 335 ALTSAISMLEPTISWLTEKFKMTRFKACMLAGSLLWLGGL-GVVASLNIGSEWTLFGKTF 393

Query: 461 LQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIIT 520
             ++D   ++W + +  +   I   WI         +Q  +G  S +   LW    R IT
Sbjct: 394 FDMLDYLTSSWLMPLGGLLMAIFSGWILKKTV----MQDELGLSSTIMHKLWLFTMRYIT 449

Query: 521 PAALVFILV 529
           P A++ + +
Sbjct: 450 PLAIIIVFL 458



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 29/123 (23%), Positives = 60/123 (48%), Gaps = 6/123 (4%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           R  W+ R  F            N+W+FPY+   +GGGAF++ +   ++I G+P+M  E++
Sbjct: 20  RVQWSTRMAFILAAVGSAVGLGNIWKFPYITGEHGGGAFVLVYLGCILIIGIPVMMAEIA 79

Query: 86  FGQYAALGP---VAVYNKFC---PLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFS 139
            G+     P   +A   +     P ++ +G   ++   +++++Y ++  W   Y+  + S
Sbjct: 80  LGRRGRHNPAQGIATLVREAGAHPFWKIIGVMALLCGFMILMFYTVVAGWAFAYVPKAAS 139

Query: 140 SIF 142
             F
Sbjct: 140 GSF 142


>UniRef50_Q6I1C4 Cluster: Sodium-dependent transporter, putative;
           n=30; Bacilli|Rep: Sodium-dependent transporter,
           putative - Bacillus anthracis
          Length = 452

 Score = 75.4 bits (177), Expect = 4e-12
 Identities = 52/178 (29%), Positives = 85/178 (47%), Gaps = 12/178 (6%)

Query: 246 KGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAV 305
           KG++ + K  Y   L  +++ + +  R +TL GA  G+ F+L PDFS+L    V   A  
Sbjct: 166 KGIEKASK--YMMPLL-FILFIAIIVRALTLDGAFAGVEFFLKPDFSKLTADTVLY-AMG 221

Query: 306 QIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELN 365
           Q FF+L+     ++T SSY K   +    +  +    +  +  AGL IF  I  L  +  
Sbjct: 222 QSFFSLTVGASVMVTYSSYLKKEEHLAKSATSIVSLTVFITVLAGLAIFPAIFALGVKPT 281

Query: 366 VSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAI 423
                   +G GL FIV P V  ++P    + I+F V+     L S  +++E V  ++
Sbjct: 282 --------EGPGLLFIVLPAVFAKIPFGQFFFIMFLVLFFFATLTSAISMLEIVVASV 331



 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 32/122 (26%), Positives = 55/122 (45%), Gaps = 3/122 (2%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           E   WT +  F             +W+FPY+  N GGGAF + F ++ +  G+PL+  E 
Sbjct: 4   ETQQWTSKIGFVLAAAGAAVGLGAIWKFPYVAGNGGGGAFFLVFLLLTLFIGMPLLLAEF 63

Query: 85  SFGQYAALGPVAVYNKFCP---LFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSI 141
             G+      V  Y    P   L+  +G   V+    V+ +Y+++  W + Y+  S +  
Sbjct: 64  VIGRSTQKEAVTAYKVLVPNSKLYPWIGRMGVVTCFSVLSFYSVVGGWILLYLYYSITGS 123

Query: 142 FY 143
           F+
Sbjct: 124 FW 125


>UniRef50_Q0A4P9 Cluster: Transporter; n=1; Alkalilimnicola
           ehrlichei MLHE-1|Rep: Transporter - Alkalilimnicola
           ehrlichei (strain MLHE-1)
          Length = 461

 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 69/259 (26%), Positives = 109/259 (42%), Gaps = 24/259 (9%)

Query: 215 LSSGIEETGEIRLGMA--MCLLAAWVIVFLCLCKGVQSSG------KVVYFTALFPYVVL 266
           L +G +  GE+  G+      L  W  VF+ LC  V S G      K V F     +++L
Sbjct: 133 LDAGADRVGELFAGLLDRPLELVLWHSVFMALCFAVVSRGVRSGLEKAVRFLMPALFLLL 192

Query: 267 VILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGD-------AAVQIFFALSPAWGGLI 319
           ++L   G+        + +   PD  +L      G        A  Q FF LS   G ++
Sbjct: 193 ILLVGYGMGAGAFAEAMRYLFLPDLGELLAGGEAGSLGALMLGAVGQAFFTLSLGMGAIM 252

Query: 320 TLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLA 379
              SY    ++   +S+I+A ++ A +  AGL +F ++         +V    D GAGL 
Sbjct: 253 VYGSYLSSRSSIPQNSVIIAGADTAIALIAGLAVFPIV--------FAVGLEPDSGAGLV 304

Query: 380 FIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVF 439
           FI       ++P   L+  LFFV+L      S  ++ME  T  +++     R++   VV 
Sbjct: 305 FITLSAGFGQMPAGALFGTLFFVLLSFAAWTSAISIMEPATAYLVENRGWSRRRAAAVVA 364

Query: 440 IVA-VFGYLGGLIFTTNSG 457
           + A   G L  L     SG
Sbjct: 365 LAAWAMGILSALSLNVMSG 383



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 30/122 (24%), Positives = 61/122 (50%), Gaps = 6/122 (4%)

Query: 27  GNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSF 86
           G W  R+ F            N+WRFPY+   +GGGAF++ + + ++  G+P+M  E+  
Sbjct: 11  GQWGSRWAFILAATGSAVGLGNIWRFPYVVGESGGGAFVVVYLLFVLGVGIPVMMGEILL 70

Query: 87  GQYAALGPVAVYNKFCPLFRG------LGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSS 140
           G++    P+   +  C  +        LG+  V+   I++ +Y+++  W++ Y+ ++   
Sbjct: 71  GRHGRQSPINTLSTLCREYGTQRAWVLLGWMGVLAGFIILSFYSVVAGWSLAYVPMTAGG 130

Query: 141 IF 142
            F
Sbjct: 131 AF 132


>UniRef50_Q8E9E5 Cluster: Sodium-dependent transporter, putative;
           n=16; Alteromonadales|Rep: Sodium-dependent transporter,
           putative - Shewanella oneidensis
          Length = 454

 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 72/307 (23%), Positives = 142/307 (46%), Gaps = 22/307 (7%)

Query: 239 IVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGV----TLPGAITGILFYLTPDFSQL 294
           +VFL L +GVQ  G   +   L P  +L+I+   GV    +L GA  GI   LTP+F++ 
Sbjct: 158 LVFLVLLQGVQE-GIEKWSKRLMP--LLLIMLIAGVAYIFSLNGASEGISALLTPNFAKA 214

Query: 295 ANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIF 354
                  +A  Q FF+L+   G ++   SY     N    ++ VA ++   +F A  +I 
Sbjct: 215 IAPDTLINALGQTFFSLTIGTGAMMVYGSYLSQKENIAKLTVWVAFTDSGIAFLAAFLII 274

Query: 355 SVIGFLAHELNVSV----DRVVDQGAGLAFIVYPEVVTRL--PISPLWSILFFVMLLTLG 408
             + ++A    V +     +++D  A L F V P + + L    + + S++FF++L+  G
Sbjct: 275 PAM-YVAQHNGVQIFSPEGKLIDSDA-LVFTVLPALFSTLGDTANLIISVVFFMLLIIAG 332

Query: 409 LDSQFALMETVTTAILDRFPNFRQKKGWVV-FIVAVFGYLGGLIFTTNSGMYWLQLMDKY 467
           L S  ++ E  T+ ++ +    RQ+   ++  ++     L  + F T   ++   +M   
Sbjct: 333 LTSAISIAEVPTSYVMQKCGFSRQRATLIIGLLLTALSLLLAVFFET---LFSFTIM--L 387

Query: 468 AANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSK-LWVYLWSAMWRIITPAALVF 526
               +  ++A+G  I + WI+   +    I +  G  +  L+  +W    + + P  ++ 
Sbjct: 388 TTQMTQPLVALGIAIYLGWIWRQSQLLKAISKQEGVDATGLFWRIWPRYVKYVCPVLIIA 447

Query: 527 ILVFNWI 533
           I +  ++
Sbjct: 448 IAIRQFV 454



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 30/121 (24%), Positives = 58/121 (47%), Gaps = 6/121 (4%)

Query: 28  NWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFG 87
           +++ R  F            N+W FP     +GGGAFL+ + V++ I G+P++  EL  G
Sbjct: 11  HFSSRLGFIMAAAGSAVGVGNIWGFPTQAATHGGGAFLLVYLVLIFILGIPMLMAELMIG 70

Query: 88  QYAALGPVAVYNKF-C-PLFRGLG--YGM--VIVSSIVMLYYNLIIAWTIFYMTVSFSSI 141
           ++    P     K  C  L R LG   G+  ++ + ++  +Y+++  W + +     ++ 
Sbjct: 71  RHGQTNPADAMGKLGCNSLTRSLGKTIGLISIVTAGLIYTFYSILSGWFVSFAIAPIATA 130

Query: 142 F 142
           F
Sbjct: 131 F 131


>UniRef50_Q83A23 Cluster: Transporter; n=4; Coxiella burnetii|Rep:
           Transporter - Coxiella burnetii
          Length = 450

 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 36/126 (28%), Positives = 63/126 (50%), Gaps = 6/126 (4%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           R  W+ +  F            N+WRFPY+    GG AFL+ + + ++I GLP+M  E+ 
Sbjct: 12  RERWSSKLAFILAATGAAVGLGNIWRFPYMAGMYGGSAFLLIYLIFVLIIGLPIMIAEIL 71

Query: 86  FGQYAALGPV------AVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFS 139
            G+ +   PV      A  +     +  LG+   +   +++ +Y+++  W + Y+  SFS
Sbjct: 72  IGRRSRKNPVDALITLAQESNHSRKWGLLGWLGALALLLILSFYSVVAGWNVAYLIKSFS 131

Query: 140 SIFYQL 145
           + FYQL
Sbjct: 132 NEFYQL 137



 Score = 42.3 bits (95), Expect = 0.038
 Identities = 48/214 (22%), Positives = 85/214 (39%), Gaps = 10/214 (4%)

Query: 239 IVFLCLCKGVQSS-GKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLANA 297
           +  + + KGV+    K   F     YV+L IL     +      G  F    + S++  +
Sbjct: 166 LTMVVVAKGVKGGLEKATKFMMPALYVILFILVIYAFSYGNFNKGFHFLFDFNHSKITTS 225

Query: 298 QVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVI 357
            V   A    FF L+   G +    +Y   + N     LIVA  ++  +  +GL IF ++
Sbjct: 226 VVIA-ALGHAFFTLALGAGAMAMYGAYVPRNVNLGKTVLIVASLDVLVAILSGLAIFPIV 284

Query: 358 GFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALME 417
              A+ L        + G GL ++  P ++  L        L F++LL     S   L E
Sbjct: 285 --FAYHL------PPNSGPGLMYVTLPIILAHLSSGWFIGGLCFLLLLFAAWTSSINLAE 336

Query: 418 TVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLI 451
            +   + +R    R     ++ + A F  +G ++
Sbjct: 337 PLVVILTERLGLKRTYAAIIIGLTAWFIGIGSVL 370


>UniRef50_A1HTE8 Cluster: Transporter; n=1; Thermosinus
           carboxydivorans Nor1|Rep: Transporter - Thermosinus
           carboxydivorans Nor1
          Length = 330

 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 34/109 (31%), Positives = 58/109 (53%), Gaps = 2/109 (1%)

Query: 48  NVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAALGPVAVYNKFCP--LF 105
           N+W+FPYL    GGGAFL+ + V +++ GLP+M  E   G+ A    V  + K  P   +
Sbjct: 34  NIWKFPYLTGQYGGGAFLMVYLVCILLVGLPVMLGEFYIGRKARRNAVGAFAKLAPRTAW 93

Query: 106 RGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFYQLPWQNCKAEW 154
           +  G   V+   ++M +Y+ +  W  FY+  +    F Q+  +  KA++
Sbjct: 94  KHTGTLAVLAVYLIMFFYSCVAGWVYFYLFKALRGEFAQVSLETAKAQF 142



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 35/102 (34%), Positives = 49/102 (48%), Gaps = 5/102 (4%)

Query: 238 VIVFLCLCKGVQSSGKVVYFTAL-FPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLAN 296
           V+V   L  GVQ   + +  T +   +++++I   R +TLPGA  G+ F    DFS+L  
Sbjct: 161 VVVSAILMLGVQKGIEKITKTLMPLLFILILICDIRALTLPGAAEGLNFLFQVDFSKLTP 220

Query: 297 AQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNN---CYIDS 335
             +   A    FF LS   G +IT SSY     N   CY  S
Sbjct: 221 TVIL-TALGLAFFKLSLGMGVMITYSSYFTADTNFLHCYESS 261


>UniRef50_Q892Y6 Cluster: Sodium dependent amino acid transporter;
           n=4; Clostridia|Rep: Sodium dependent amino acid
           transporter - Clostridium tetani
          Length = 247

 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 57/226 (25%), Positives = 98/226 (43%), Gaps = 17/226 (7%)

Query: 276 LPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDS 335
           +PGA+ G+ + + P +  L     W  A  Q FF +S    G++   SY K   +    S
Sbjct: 1   MPGAMEGVAYLVKPRWGYLLKPITWVMALGQAFFTVSLNGAGMVVYGSYLKEEEDIPKAS 60

Query: 336 LIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPL 395
           + +A+ +  ++  A  VI   +   A  LN S       G  L FI  P V   +P    
Sbjct: 61  MQIAIFDTLSALLAAFVIIPAV--FAFGLNPSA------GPSLLFITMPYVFKSMPFGYA 112

Query: 396 WSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGG--LIFT 453
           + +LFF+ ++   + S   +ME  + A L +F   R K    V I+++  ++ G  L  +
Sbjct: 113 FGVLFFISIIFAAVSSLINMMEATSEAFLSQFKIGRIKG---VAIISIIAFIIGMPLNLS 169

Query: 454 TNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQR 499
            N+   W   +  Y A    ++ A    +   WIYG +    +I +
Sbjct: 170 MNAFGKWADFVTIYLAPLGTMVSA----VTFFWIYGMDNALVEINK 211


>UniRef50_Q0IBN8 Cluster: Na+-dependent transporter of the SNF
           family protein; n=20; Cyanobacteria|Rep: Na+-dependent
           transporter of the SNF family protein - Synechococcus
           sp. (strain CC9311)
          Length = 461

 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 68/281 (24%), Positives = 125/281 (44%), Gaps = 15/281 (5%)

Query: 263 YVVLVILFFRGVTLPGAITGI-LFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITL 321
           +V+LV L     TL GA+ G   F L  D +QL N     +A  Q FF++    G ++  
Sbjct: 192 FVLLVGLALWAATLSGAVGGYQTFLLRWDAAQLLNPTTIRNAFTQAFFSIGTGIGCILAY 251

Query: 322 SSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFI 381
           S+Y   S     +++ V   + A    AGLV F V+     +  VS   V     G  F+
Sbjct: 252 SAYLNSSARLPREAIAVVGLDTAVGLLAGLVTFPVVISFGLQETVSESTV-----GALFL 306

Query: 382 VYPEVVTRL-PISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFI 440
             P  +  L     L ++LFF +     + S  +L+E    +++DR    R++  W   +
Sbjct: 307 AIPTGLASLGSAGRLVAVLFFSLAYLAAITSSVSLLEVPVASLMDRLGWSRRRSAW---L 363

Query: 441 VAVFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRM 500
           +A+  ++ GL    +  +  L++MD       +++  +   +L+ W+   ++F  D+Q  
Sbjct: 364 MALLIFIAGLPAAMSIPV--LEVMDSIFGGVLLILGGLLIALLVGWVV-PKRFRNDLQGS 420

Query: 501 IGRQSKLWVYLWSAMW--RIITPAALVFILVFNWIEYKPAS 539
                 + + L+   W    +  A L+  +V  W ++ PA+
Sbjct: 421 KTSAGLIGLMLFFLRWVSPAVITAGLLISVVDLWRQWFPAA 461



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 28/107 (26%), Positives = 52/107 (48%), Gaps = 7/107 (6%)

Query: 28  NWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFG 87
           +W   F F            N+W F Y     GGGAFL+ + +++++  LP++  E+  G
Sbjct: 22  HWRSGFGFVLAAAGSAVGLGNLWGFAYRASQGGGGAFLLLYVLIVLVVCLPVLVAEMVLG 81

Query: 88  QYAA----LGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWT 130
           +  A    L P+A   K    +  +G+  V+ S  ++ +Y +++ WT
Sbjct: 82  RSTAQSPLLAPIAAAGK---AWWPMGWLFVLASCGILAFYAVLMGWT 125


>UniRef50_A7HQJ6 Cluster: Sodium:neurotransmitter symporter
           precursor; n=1; Parvibaculum lavamentivorans DS-1|Rep:
           Sodium:neurotransmitter symporter precursor -
           Parvibaculum lavamentivorans DS-1
          Length = 457

 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 34/120 (28%), Positives = 58/120 (48%), Gaps = 6/120 (5%)

Query: 29  WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQ 88
           W+ RF F            N+WRFPYL   NGGGAF++ + +  +   LP++  E+  G+
Sbjct: 10  WSSRFAFLMAAIGSAVGLGNIWRFPYLAGENGGGAFIVIYAITTMGIALPILVSEIMLGR 69

Query: 89  YAALGPVAVYNKFCPLFRG------LGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIF 142
                P+    K     R       +G+G  + + IV+ YY++I  W + Y+ ++ +  F
Sbjct: 70  MGRQSPINTMRKLIAENRAARFWTLIGWGGTVGAFIVLSYYSVIGGWALKYVELALTGAF 129



 Score = 58.0 bits (134), Expect = 7e-07
 Identities = 75/331 (22%), Positives = 137/331 (41%), Gaps = 33/331 (9%)

Query: 216 SSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVT 275
           S+ + +   + L   + L A   IV   +  G++ +  VV    L  + +LV +     T
Sbjct: 142 SAFVTDPYSVALWQTLFLAATIFIVAAGVTSGIERA--VVLLMPLL-FFLLVGMAIYATT 198

Query: 276 LPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDS 335
            PG    ++F    +F ++    +   A  Q FF++S A G ++T  +Y     +    +
Sbjct: 199 TPGFGEAMIFMFAFEFHEVTPDTILA-AIGQGFFSVSVALGAMMTYGAYLDKDVSIGRSA 257

Query: 336 LIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPL 395
           +++AV++   +  AG+ IF ++   ++ L  S       G GL FI  P     +    L
Sbjct: 258 IVIAVADTLVALLAGIAIFPLV--FSYGLEPS------SGPGLTFITLPIAFGTIGGGVL 309

Query: 396 WSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTN 455
               FF++L    + S  +L+E V   + +        + W+  IV    ++ G I T  
Sbjct: 310 IGAAFFLLLSVAAITSAISLLEPVVAWVEE---GIHIPRKWLALIVGGAAWVAG-IGTVL 365

Query: 456 SGMYW--------LQLM-DKYA------ANWSVLIIAIGECILIAWIYGAEKFCGDIQRM 500
           S   W        L LM DK           ++++  +G  +L++   G        +  
Sbjct: 366 SFNLWADFHPLAGLGLMADKTVFDVLDFTTSNIVMPTVG--LLMSLFAGWVLSSSAAEEA 423

Query: 501 IGRQSKLWVYLWSAMWRIITPAALVFILVFN 531
           +G + KLW  LW    R + P  ++ I V N
Sbjct: 424 LGARGKLWFRLWRFALRYVAPLGVMSIFVAN 454


>UniRef50_Q8DBI3 Cluster: Sodium-dependent transporter; n=50;
           Vibrionales|Rep: Sodium-dependent transporter - Vibrio
           vulnificus
          Length = 454

 Score = 72.9 bits (171), Expect = 2e-11
 Identities = 67/300 (22%), Positives = 137/300 (45%), Gaps = 15/300 (5%)

Query: 237 WVIVFLCLCKGVQSSGKVVYFTALFP--YVVLVILFFRGVTLPGAITGILFYLTPDFSQL 294
           +V+  L +  GV+  G   + T L P  +V+  +LF   +T  GA+ G+  YL PDF ++
Sbjct: 157 YVLTILIVQGGVKQ-GIEKWSTRLMPALFVLFAVLFIYIMTQNGAMEGLKHYLVPDFDKV 215

Query: 295 ANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIF 354
            + ++   A  Q FF+L+     ++   SY     N    ++ V + + A +F AGLV+ 
Sbjct: 216 WDRKLILAAMGQGFFSLTIGGCSMLIYGSYLSKKENLPKMAMNVTLVDTAVAFIAGLVVL 275

Query: 355 SVIGFLAHELNVSV---DRVVDQGAGLAFIVYPEVVTRLP-ISPLWSILFFVMLLTLGLD 410
             + F+A +  V +   D  +     L F V P +   L  +  +++++FF++L    L 
Sbjct: 276 PAM-FVAMQKGVQIYAEDGSLLSSDTLVFTVLPLMFDSLGLLGQIFAVVFFLLLTIAALT 334

Query: 411 SQFALMETVTTAILDRFPNFRQKKGWVV-FIVAVFGYLGGLIFTTNSGMYWLQLMDKYAA 469
           S  +++E     + +RF   R    WV+  ++A+F     ++   N G  +  L+   A 
Sbjct: 335 SSISMLECPVALVGERFNTKRSTTSWVLGGLIALF----SVVIVYNFGALF-GLVATIAT 389

Query: 470 NWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWV-YLWSAMWRIITPAALVFIL 528
            +     A+  C+   W++       ++++     +  W   +W +  + + P  +  ++
Sbjct: 390 QYLQPTAALLFCLFGGWVWSRHSKIKELEQGNPEFTLGWFGKVWPSYVKFVCPVLVATVI 449



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 33/116 (28%), Positives = 58/116 (50%), Gaps = 8/116 (6%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           R ++  R  F            N+W FP    +NGGGAFL+ + VM++I   P++ +E++
Sbjct: 10  REHFGSRLGFILAAAGAAVGLGNIWGFPTQAASNGGGAFLLVYLVMILIVAFPMLVVEMA 69

Query: 86  FGQYAALGPVAVYNKFC--PLFRGLGYGMV-----IVSSIVMLYYNLIIAWTIFYM 134
            G++    PV         P+ + +G G+V      V S V+ +Y+++  W I +M
Sbjct: 70  IGRHGQANPVDSMRALTSHPVGKKVG-GLVGWIGLSVPSAVLAFYSIVGGWIICFM 124


>UniRef50_A7CWE7 Cluster: Sodium:neurotransmitter symporter; n=1;
           Opitutaceae bacterium TAV2|Rep: Sodium:neurotransmitter
           symporter - Opitutaceae bacterium TAV2
          Length = 536

 Score = 72.9 bits (171), Expect = 2e-11
 Identities = 78/308 (25%), Positives = 144/308 (46%), Gaps = 20/308 (6%)

Query: 205 EEYFTNQVLGLSSGIE-ETGEIRLGMAMCLLAAWVIVFLC--LCKGVQSSGK----VVYF 257
           +E+F       S+G+  + G   +G+ + L+    + FL   L KG++ + +    V+  
Sbjct: 136 KEFFATYTGAGSNGVALQFGLSDVGLFVVLVIVVNLFFLYRGLSKGIELACRWGMPVLIL 195

Query: 258 TALFPYVVLVILFFRGVTLP--GAITGILFYLTP-DFSQ-LANAQVWGDAAVQIFFALSP 313
            A+   V ++ L     T P    ++ + F   P D  Q L + Q+W  A  QIFF+LS 
Sbjct: 196 IAIVIMVRVLTLGTPDATRPELNVLSALGFMWNPGDILQSLKSPQLWLAAGSQIFFSLSI 255

Query: 314 AWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVD 373
             G +IT +SY + +++  + SL    +N     F  +V+  +    A  + +    V  
Sbjct: 256 GLGIIITYASYLRKTDDITLSSLTAVGANE----FCEVVLGGLTTVSAAFMFLGAAGVAG 311

Query: 374 QGA-GLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQ 432
           QG   L FIV PEV + +   P+++ LFFV+L    + S  ++++  T A L+    FR 
Sbjct: 312 QGTFALGFIVLPEVFSHMTGGPVFAALFFVLLFLAAITSSLSILQP-TIAFLEE--AFRM 368

Query: 433 KKGWVVFIVAVFGYLG-GLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAE 491
           ++   +  +A    +G G ++  +  +  L  +D +     V +  +   IL AW+ G +
Sbjct: 369 RRAVSITWLATLLVIGTGFVWFFSKDLKALDTIDFWVGTVGVYLQGLLIVILFAWVIGID 428

Query: 492 KFCGDIQR 499
           K   ++ R
Sbjct: 429 KSWREMHR 436



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 34/111 (30%), Positives = 50/111 (45%), Gaps = 6/111 (5%)

Query: 29  WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQ 88
           W+ RF              N  RFP L    GGGAF+I + V L++ G+P+ + E + G+
Sbjct: 9   WSSRFGVILAVASSAVGLGNFLRFPGLAAQYGGGAFMIAYFVSLLVIGIPVSWAEWTVGR 68

Query: 89  YAA-LGPVAVYNKFCPLFRG-----LGYGMVIVSSIVMLYYNLIIAWTIFY 133
           +    G  +    F  L R      LG    +V  +V +YY  I AW + Y
Sbjct: 69  HGGHFGYHSSPGIFHALLRRPWAKYLGALGFMVPLMVCMYYVYIEAWCLGY 119


>UniRef50_Q7M9R0 Cluster: Transporter; n=1; Wolinella
           succinogenes|Rep: Transporter - Wolinella succinogenes
          Length = 443

 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 37/115 (32%), Positives = 59/115 (51%), Gaps = 7/115 (6%)

Query: 32  RFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQYAA 91
           R  F            NVW+FPY+   NGGGAF+  F + +V  GL +   E+  G+ + 
Sbjct: 6   RIGFILAAAGSAIGLGNVWKFPYMTGQNGGGAFVAIFLLSVVFIGLTVFLAEMILGRTSE 65

Query: 92  LGPVAVYNKFCPLFRGLGY----GMVIVSSIVML-YYNLIIAWTIFYMTVSFSSI 141
             PV+ Y    P   G  Y    G +I+S +++L +Y++++ W I Y+ VS S +
Sbjct: 66  KNPVSTYESLAP--HGGRYWKYAGFMILSGVLILSFYSVVVGWLIHYIFVSLSGL 118



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 65/276 (23%), Positives = 116/276 (42%), Gaps = 21/276 (7%)

Query: 263 YVVLVILFFRGVTLPGAITGILFYLTPDFSQLANAQVWGDAAVQIFFALSPAWGGLITLS 322
           +++ + L F  +++      + F  TP + ++ NA V   +  Q FF LS   G ++T S
Sbjct: 175 FLIFIALLFYALSMDSFGKSLAFMFTPHWEKI-NANVVLMSVGQAFFTLSLGVGTIMTYS 233

Query: 323 SYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIV 382
           +      N    +L VA  +   +  AGLVIF+ +     + +         G GL FI 
Sbjct: 234 ASLPKKGNFVSSALYVAFLDTLLAVVAGLVIFTFLFEFGSDPS--------GGPGLVFIS 285

Query: 383 YPEVVTRLP-ISPLWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVV--- 438
            P +  ++  +  L S+LFF+ LL  G+ S  +L E +   +++R    R K  W V   
Sbjct: 286 LPVIFAQMGLVGQLISLLFFIALLFAGITSAISLAEPLLGYLIERRSWKRSKAVWAVMGV 345

Query: 439 -FIVAVFGYLGGLIFTTNS----GMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKF 493
            + + V   LGG      S    G      +D  ++   + +  +  CI + ++    + 
Sbjct: 346 SYALGVLAILGGSKAYGESLKWGGKSIFDWLDFGSSALLMPLAGVALCIFVGFVLDKNRV 405

Query: 494 CGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILV 529
            G      G     +  +W    R + P A+  IL+
Sbjct: 406 YG---MFGGYMPPFFFKIWLFCVRFVAPVAIFIILI 438


>UniRef50_Q9JRT7 Cluster: Sodium-dependent transporter, putative;
           n=9; Chlamydiaceae|Rep: Sodium-dependent transporter,
           putative - Chlamydia pneumoniae (Chlamydophila
           pneumoniae)
          Length = 494

 Score = 71.7 bits (168), Expect = 5e-11
 Identities = 49/186 (26%), Positives = 85/186 (45%), Gaps = 8/186 (4%)

Query: 236 AWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILFYLTPDFSQLA 295
           A++++   +  G++   K++   A F  +  + L  R VTLPGA+ GI    + D S  +
Sbjct: 152 AYLVIRKGIVHGIEKCNKIL-IPAFF--LCTIALLLRAVTLPGAVQGIKQLFSCDKSCFS 208

Query: 296 NAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFS 355
           N +VW +A  Q  +     WG L+  + +         +  + A+ N   S   G++IFS
Sbjct: 209 NYKVWIEALTQNAWDTGAGWGLLLVYAGFASKKTGVVSNGALTAICNNLVSLIMGIIIFS 268

Query: 356 VIGFLAHELNVSV-DRVVDQGAGLAFIVYPEVVTRLP----ISPLWSILFFVMLLTLGLD 410
               L       + D       G+ FI  PE+ TRLP    ++ L+S +FF+      L 
Sbjct: 269 TCASLDILGTTQLQDGAGASSIGITFIYLPELFTRLPGGIYLTTLFSSIFFLAFSMAALS 328

Query: 411 SQFALM 416
           S  +++
Sbjct: 329 SMISML 334



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 35/116 (30%), Positives = 57/116 (49%), Gaps = 3/116 (2%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           +  +++ R  F            N+WRFP +   NGGGAFLI +   L +  +PL+ +EL
Sbjct: 4   KHASFSSRLGFIFSMIGIAVGAGNIWRFPRVAAQNGGGAFLILWLCFLFLWSIPLIIIEL 63

Query: 85  SFGQYAALGPVAVYNKFC-PLFRGLGYGMVIVSSIVMLYYNLIIAW--TIFYMTVS 137
           S G+     P+    K     F   G  + +V++ ++ YY+ I+ W  + FY  VS
Sbjct: 64  SIGKLTKKAPIGALIKTAGKKFAWAGGFITLVTTCILAYYSTIVGWGLSYFYYAVS 119


>UniRef50_UPI0000D56C34 Cluster: PREDICTED: similar to solute
           carrier family 6 (neurotransmitter transporter,
           dopamine), member 3; n=1; Tribolium castaneum|Rep:
           PREDICTED: similar to solute carrier family 6
           (neurotransmitter transporter, dopamine), member 3 -
           Tribolium castaneum
          Length = 533

 Score = 71.3 bits (167), Expect = 7e-11
 Identities = 61/329 (18%), Positives = 136/329 (41%), Gaps = 9/329 (2%)

Query: 205 EEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYV 264
           E+++ N+VL         G  +  + +  L   +++F     G +++ K +   A  P V
Sbjct: 123 EQFYFNRVLNTDETSGYVGAPQPELLVYGLVTIILIFFANYGGPKTTEKFLLVLATVPTV 182

Query: 265 VLVILFFRGVTLPGAITGILFYLTP-DFSQLANAQVWGDAAVQIFFALSPAWGGLITLSS 323
            +V+LFF  ++       + +  T  D   L+N + W         +    +G  I   +
Sbjct: 183 QMVVLFFAPLSDQNGFVTLNYLFTQLDVKNLSNFKTWTRIINLSLSSPGLGFGAFIAFGT 242

Query: 324 YNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVY 383
            + F    +  ++I++V+++  +    +++ + +  L  +  +  D        L     
Sbjct: 243 QSTFRTPLHFKAIIISVTSVLFTVLYSIIVQNFLISLCIQSQMLFDDFFKLEQELEM--- 299

Query: 384 PEVVTRLPISP-LWSILFFVMLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVA 442
           PE V  L  S   W  ++       GL S   +M   T  + +  P  R++    V   +
Sbjct: 300 PEAVFFLEHSSRFWITMWLSNCYMTGLRSLIVMMCLNTEVVYNSLPKARKRHTLCVLTFS 359

Query: 443 VFGYLGGLIFTTNSGMYWLQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIG 502
           +  Y G +  +T  G    + ++    ++ V  +   + + + + YG  KF  D+  M+G
Sbjct: 360 LIIYTGTIFLSTRIGYSVFKTIESVLNDFCVPFLNTLQLVGVVYFYGITKFRDDVHFMLG 419

Query: 503 RQSKLWVYLWSAMWRIITPAALVFILVFN 531
            +S ++   W+ ++ ++ P  L  +L +N
Sbjct: 420 IRSSVY---WNTLY-VLNPLLLGIVLAYN 444



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 26/80 (32%), Positives = 44/80 (55%), Gaps = 2/80 (2%)

Query: 53  PYLCYNNGGGAFLIPFTVMLV-IAGLPLMFMELSFGQYAALGPVAVYNKFCPLFRGLGYG 111
           P+L   N G   LIP  ++++ +  +P MFMEL+ GQY+    + V++  CPL RG+G  
Sbjct: 16  PWLLKTNVGILLLIPVQLLVMFLTTIPCMFMELALGQYSNRAVIRVWD-LCPLLRGIGLC 74

Query: 112 MVIVSSIVMLYYNLIIAWTI 131
             +   +    +N I  +T+
Sbjct: 75  SFLTFLLYQSSWNKINCFTL 94


>UniRef50_A5ZNA7 Cluster: Transporter; n=4; Bacteria|Rep:
           Transporter - Ruminococcus obeum ATCC 29174
          Length = 495

 Score = 70.9 bits (166), Expect = 9e-11
 Identities = 60/221 (27%), Positives = 96/221 (43%), Gaps = 15/221 (6%)

Query: 209 TNQVLGLSSGI-EETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVLV 267
           +++V G  S +   TG +   M + +L A+ +  L L  G++   KV+    L    ++V
Sbjct: 133 SDEVSGFFSNLMTSTGTMTGWMIVAVLLAFGVCSLGLQNGIERITKVMMICLL---ALIV 189

Query: 268 ILFFRGVTLPGAITGILFYLTPDFSQLANA---QVWGDAAVQIFFALSPAWGGLITLSSY 324
           +L    VTL GA+ G+ FYL P+   +  A    V   A  Q FF LS   G +    SY
Sbjct: 190 VLAVHSVTLDGAMEGVKFYLVPNLDNIRAAGLGNVIFGALSQAFFTLSIGIGAMEIFGSY 249

Query: 325 NKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYP 384
                    +S+ + + +   +  AGL+I           NV        G GL FI  P
Sbjct: 250 MGKECTLAGESINILILDTFVALMAGLIIIPA----CFAFNVEPGA----GPGLVFITLP 301

Query: 385 EVVTRLPISPLWSILFFVMLLTLGLDSQFALMETVTTAILD 425
            V  ++    LW  LFF+ +    L +  A+ E + +  +D
Sbjct: 302 NVFNQMAGGRLWGALFFLFMSFAALSTVIAVFENILSFAMD 342



 Score = 67.7 bits (158), Expect = 9e-10
 Identities = 32/112 (28%), Positives = 56/112 (50%), Gaps = 3/112 (2%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           ER  +  R  F            NVW+FPY+    GG AF++ + V LV+ GLP++  E 
Sbjct: 8   ERETFGSRLGFILVSAGCAVGLGNVWKFPYMTGKYGGAAFILIYLVFLVLLGLPILVSEF 67

Query: 85  SFGQYAALGPVAVYNKFCP---LFRGLGYGMVIVSSIVMLYYNLIIAWTIFY 133
           + G+ + L     ++K  P    F    Y  +I + ++M++Y ++  W ++Y
Sbjct: 68  AVGRSSRLSTARAFHKLEPEGSNFHKYSYMGMIGNYMLMMFYTMVAGWMMYY 119


>UniRef50_A5ZA96 Cluster: Transporter; n=3; Clostridiales|Rep:
           Transporter - Eubacterium ventriosum ATCC 27560
          Length = 471

 Score = 70.9 bits (166), Expect = 9e-11
 Identities = 89/351 (25%), Positives = 158/351 (45%), Gaps = 38/351 (10%)

Query: 200 RRPPAEEYFTNQVLGLSSGIEETGEIRLGMAMCLLAAWVIVFLCLCKGVQSSGKVVYFTA 259
           ++  A+  FTN +   SS       +  G+   LL A +IV+  + KG++   K +    
Sbjct: 121 KKAVADNCFTNFITSPSS-------VWYGIIFMLLTA-IIVYNGVEKGIERVSKFI-MPV 171

Query: 260 LFPYVVLVILFFRGV-------TLPGAITGILFYLTPDFSQLANA---QVWGDAAVQIFF 309
           L   VV + +F   +       T+   + G+  YLTPD S +      QV  DA  Q+FF
Sbjct: 172 LLVMVVGIAIFSLTLKTTLDDGTVRTGLQGLKVYLTPDMSGITVQKFLQVSLDAMSQLFF 231

Query: 310 ALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFSVIGFLAHELNVSVD 369
           +LS + G +IT  SY K   N       + + +   +F AG++I   + F+   L+    
Sbjct: 232 SLSVSMGIMITYGSYVKKDVNLNKAVSQIEIMDTGVAFLAGMMIIPAV-FVFSGLD---- 286

Query: 370 RVVDQGAGLAFIVYPEVVTRLPIS-PLWSILFFVMLLTLGLDSQFALMETVTTAILDRFP 428
             +  G GL F+  P V  R+ ++  +  +LFF++     L S  +++E++T   ++ F 
Sbjct: 287 -GMSAGPGLMFVSLPNVFFRMGMAGRIVGLLFFLLAGFAALTSCISVLESITANCMELFH 345

Query: 429 NFRQKKGWVVFIVAVFG----YLGGLIF------TTNSGMYWLQLMDKYAANWSVLIIAI 478
             R+K   V+ I+ +       LG  IF         S    L +MD  + ++ +  I++
Sbjct: 346 TERKKTTGVLSIIYLIATAVIALGYSIFYVEVKLPNGSTGQLLDIMDYISNSFLMPFISL 405

Query: 479 GECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALVFILV 529
              ILI WI        +++    + S+  +Y  + M R I P  +V + +
Sbjct: 406 LSAILIGWIIKPSWIVEEMELNGKKFSRKKLY--NVMIRYIMPVIMVILFL 454



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 31/112 (27%), Positives = 55/112 (49%)

Query: 25  ERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMEL 84
           ++  ++G+  F            N+WRFPYL   +GGG FLI + V+++  G  L+  ++
Sbjct: 3   QKSGFSGQIGFVLAAAGSAVGVGNLWRFPYLAAKDGGGLFLIIYLVLVLTVGFTLLTTDI 62

Query: 85  SFGQYAALGPVAVYNKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTV 136
           + G+      +  Y      ++ LG    IV  I+M YY +I  W + Y+ +
Sbjct: 63  AIGRKTGKSAIYAYESMRKKWKFLGVITFIVPVIIMTYYAVIGGWILKYIAI 114


>UniRef50_A2BJD7 Cluster: Na+ dependent transporter; n=2;
           Desulfurococcales|Rep: Na+ dependent transporter -
           Hyperthermus butylicus (strain DSM 5456 / JCM 9403)
          Length = 530

 Score = 70.9 bits (166), Expect = 9e-11
 Identities = 72/310 (23%), Positives = 138/310 (44%), Gaps = 15/310 (4%)

Query: 233 LLAAWVIVFLCLCKGVQSSGKVVYFTALFPYVVL--VILFFRGVTLP--GAITGILFYLT 288
           LL   +IV   + +G++ + K++        V+L  V L       P    + G  +  T
Sbjct: 167 LLVITLIVSRRVRRGIEIAAKIMMPILFIEAVILATVSLTLGAPVKPEWSTLKGFEWLWT 226

Query: 289 PDFSQLANAQVWGDAAVQIFFALSPAWGGLI-TLSSYNKFSNNCYIDSLIV-AVSNIATS 346
           P+F +L +   + + A QIFF LS   GG+I   +SY +  ++  + +L   +++  A  
Sbjct: 227 PNFEKLKDPATFIEGAGQIFFTLSIGIGGIIPNYASYLRREDDLPLSALTTTSLNEFAEV 286

Query: 347 FFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIV-YPEVVTRLP-ISPLWSILFFVML 404
              G ++  ++        +           LA +V  P +   L  +  L   L++ +L
Sbjct: 287 VLGGSIVIPLLYAFGGPSIIQDIAAGKLSIFLASMVALPPLFNHLGGLGALAGFLWYSLL 346

Query: 405 LTLGLDSQFALMETVTTAILDRFPNFRQKKGWV----VFIVAVFGYLGGLIFTTNSGMYW 460
              G+ S  A++  +T+   + +   R+   W+    VFI  VF  + G + T     Y 
Sbjct: 347 WFAGITSAIAIVNVLTSMFEEDYGIARRYSAWIAFMMVFITGVFVNIEGAMKTDQLTDY- 405

Query: 461 LQLMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIIT 520
           L L+D YA +  +L++A+ E +   W++G E+   ++    G    +  + W  +  IIT
Sbjct: 406 LDLVDFYAGSLLLLVVALFEVVAALWLWGIEESYRELHN--GAYITVPKWYWKYVVGIIT 463

Query: 521 PAALVFILVF 530
           P  L+ +L +
Sbjct: 464 PIYLIIMLAW 473



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 38/134 (28%), Positives = 59/134 (44%), Gaps = 14/134 (10%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           R  W  R               N  RFP      GGGA+LIP+ + LV+ G+PLMF+E +
Sbjct: 6   REYWATRIGLILAMAGNAIGLGNFLRFPGKAAAYGGGAYLIPYFIALVLLGIPLMFVEWT 65

Query: 86  FGQYAALG------PVA-------VYNKFCPLFRGLGYGMVIVSSIVML-YYNLIIAWTI 131
            G++  L       P+        +  K    F  +G  +  ++ +++  YY  II W  
Sbjct: 66  LGRHGGLHGHGYLTPMLYIVSRNRLTKKNAAAFAIIGGTIAFLTGVMITGYYTNIIGWMG 125

Query: 132 FYMTVSFSSIFYQL 145
           +Y T + S  F +L
Sbjct: 126 YYATAAISGKFAEL 139


>UniRef50_Q31G35 Cluster: Neurotransmitter: sodium symporter (NSS)
           family transporter; n=2; Gammaproteobacteria|Rep:
           Neurotransmitter: sodium symporter (NSS) family
           transporter - Thiomicrospira crunogena (strain XCL-2)
          Length = 451

 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 36/123 (29%), Positives = 62/123 (50%), Gaps = 6/123 (4%)

Query: 29  WTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELSFGQ 88
           WT +  F            N+W+FPY+   NGGGAF++ + + +V+ GLP++  E+S G+
Sbjct: 11  WTSQTVFIMAAIGSAVGLGNLWKFPYITGENGGGAFVLVYLLCIVLIGLPILIAEISLGR 70

Query: 89  YA-ALGPVAVYNKF-----CPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIF 142
              A  P A+ N         L+  LG+  V+   +++ +Y++I  W + Y   S S  F
Sbjct: 71  AGQANPPQAMANNVKTTGANKLWVFLGFNAVLGGLLILSFYSVIAGWGVAYFIESISGSF 130

Query: 143 YQL 145
             +
Sbjct: 131 IDM 133



 Score = 57.6 bits (133), Expect = 9e-07
 Identities = 73/305 (23%), Positives = 132/305 (43%), Gaps = 31/305 (10%)

Query: 238 VIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRG-VTLPGAIT-GILFYLTPDFSQLA 295
           ++  L + KGV+S G       + P +++++L   G  T  GA      F   P+F+ L 
Sbjct: 161 LLTVLIVVKGVRS-GIERAINIMMPGLLIILLILLGYATTTGAFAQSFEFLFKPNFAALT 219

Query: 296 NAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSNIATSFFAGLVIFS 355
           +  V   A    FF LS  +G ++   SY   + +    SL + V++   +  AGLVIFS
Sbjct: 220 SESVL-IALGHAFFTLSLGFGTMMVYGSYLPKNYSIVKASLWIVVADTLIALIAGLVIFS 278

Query: 356 VIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFAL 415
           ++    + L          G GL F   P    ++     +  LFF +++   L S  ++
Sbjct: 279 IV--FGNGLEAG------SGPGLLFETLPIAFGQMSGGWFFGTLFFGLVVFAALSSSISM 330

Query: 416 METVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGL--IFTTN--SGMYWL------QLMD 465
           +E   + +   +   R+K  W   ++  F +L GL  +F+ N   G  +L      + +D
Sbjct: 331 IEPAISWLEQNWGYTRKKAAW---LLGSFAWLLGLGSVFSFNLWKGQTFLEDKTFFESLD 387

Query: 466 KYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPAALV 525
              +N  + +  +   + + W++     C       G   K W  ++S + + I P  LV
Sbjct: 388 FLTSNIMLPLGGMFTALFVGWVW----TCQQRNDETGMPPK-WSGVYSVIVKWIAP-ILV 441

Query: 526 FILVF 530
           FI+ F
Sbjct: 442 FIVFF 446


>UniRef50_A6FME6 Cluster: Sodium-dependent transporter family
           protein; n=1; Roseobacter sp. AzwK-3b|Rep:
           Sodium-dependent transporter family protein -
           Roseobacter sp. AzwK-3b
          Length = 494

 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 31/124 (25%), Positives = 60/124 (48%), Gaps = 4/124 (3%)

Query: 23  EPERGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFM 82
           + +   ++G   F            N+W+FPY+   NGGGAF++ + + ++  G PLMF 
Sbjct: 45  QSQNAGFSGSMAFILAASGSAVGLGNIWKFPYVTGENGGGAFVLFYLMCILALGAPLMFA 104

Query: 83  ELSFGQYAALGPVAVY----NKFCPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSF 138
           E+  G+    GPV  +     K       +GY  ++ + + +  Y +I  W ++Y +++ 
Sbjct: 105 EIFIGKRGKAGPVDSFKNLGTKAAARAHPVGYIFILTAFVALSVYGVIGGWAVYYTSLAL 164

Query: 139 SSIF 142
            + F
Sbjct: 165 DNGF 168



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 55/196 (28%), Positives = 89/196 (45%), Gaps = 17/196 (8%)

Query: 244 LCKGVQSSGKVVYFTALFP--YVVLVILFFRGVTLPGA-ITGILFYLTPDFSQLANAQVW 300
           + KGV S+G   Y T L P  +++L+ L    +T  GA +  + F   PDF++L  + + 
Sbjct: 205 VAKGV-STGIERYTTILMPLFFMMLLGLTAYALTTSGAGMRSVSFMFNPDFTKLTPSAM- 262

Query: 301 GDAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVA---VSNIATSFFAGLVIFSVI 357
            +A    FF+LS   GG++    Y   S +    +  VA   V +   +  AGL+IFSVI
Sbjct: 263 AEALGHAFFSLSLGVGGMLVYGQYMPSSPSATPITRSVATIVVVDTLVALCAGLLIFSVI 322

Query: 358 GFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFVMLLTLGLDSQFALME 417
               H    +       G GL F+  P     +      ++L+F +++   L S  + +E
Sbjct: 323 --FGHGGEAA------GGPGLLFMSLPVAFGEMTGGYYVAVLWFALVVVAALTSGISYLE 374

Query: 418 TVTTAILDRFPNFRQK 433
            +  A  DR    R K
Sbjct: 375 -IIVAHADRLGMGRAK 389


>UniRef50_Q9HPQ1 Cluster: Sodium-and chloride-dependent transporter;
           n=3; Halobacteriaceae|Rep: Sodium-and chloride-dependent
           transporter - Halobacterium salinarium (Halobacterium
           halobium)
          Length = 477

 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 31/125 (24%), Positives = 61/125 (48%), Gaps = 2/125 (1%)

Query: 26  RGNWTGRFDFXXXXXXXXXXXXNVWRFPYLCYNNGGGAFLIPFTVMLVIAGLPLMFMELS 85
           R  W  R  F            N+WRFP++   NGG AFL+ +  +++  G+P +  E  
Sbjct: 3   RDVWHSRLGFIMAAVGSAVGLGNLWRFPWMTSENGGAAFLLVYLGVVLCVGVPGLLAEFV 62

Query: 86  FGQYAALGPVAVYNKF--CPLFRGLGYGMVIVSSIVMLYYNLIIAWTIFYMTVSFSSIFY 143
            G+ +   PV  ++      L+R  G+  V+++ +++ +Y+++  W + Y   S +  ++
Sbjct: 63  IGRRSRRSPVGAFSSLSDSTLWRVFGHLSVVIAVVLLSFYSVVGGWILRYFGASLTGAYF 122

Query: 144 QLPWQ 148
             P Q
Sbjct: 123 SNPGQ 127



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 70/307 (22%), Positives = 127/307 (41%), Gaps = 21/307 (6%)

Query: 227 LGMAMCLLA-AWVIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFFRGVTLPGAITGILF 285
           +G  +  LA   +IV   + +G++++ K++    +   V+L++L     TL GA  G+ F
Sbjct: 139 VGFHLLFLAITGLIVVRGIKRGIENATKLMMPAVV---VLLIVLAAWASTLDGAGAGLAF 195

Query: 286 YLTPDFSQLANAQVWG---DAAVQIFFALSPAWGGLITLSSYNKFSNNCYIDSLIVAVSN 342
           YL+PD  +L  A + G    AA Q  F LS   G +IT +SY     +   D   +AV N
Sbjct: 196 YLSPDV-ELLEADLLGILPAAAGQALFTLSLGSGTMITYASYLDEERSLAADGAAIAVLN 254

Query: 343 IATSFFAGLVIFSVIGFLAHELNVSVDRVVDQGAGLAFIVYPEVVTRLPISPLWSILFFV 402
                 AGLV+F ++  L  +           G G  F+        +P       +FF 
Sbjct: 255 TCIGVLAGLVVFPLLFALVGDAGTG-------GPGALFVGLANAFVAVPYGRAVGAVFFA 307

Query: 403 MLLTLGLDSQFALMETVTTAILDRFPNFRQKKGWVVFIVAVFGYLGGLIFTTNSGMYWLQ 462
           ++    + S  +++E   + ++D +   R++       V VF   G      + G++   
Sbjct: 308 VVSLAAISSSISMLELPVSFLVDEYGVSRRRA--TALFVGVFTVTGSAT-ALSPGLF--D 362

Query: 463 LMDKYAANWSVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAMWRIITPA 522
            +     +  +    IG  +   W+ G +    + +   G  +      W     ++ P 
Sbjct: 363 FVAGTLVDLLMTAGLIGFLLFTGWVVG-QNAVTEYELGAGAVASALSTPWLYAVGVVIPV 421

Query: 523 ALVFILV 529
            L+F LV
Sbjct: 422 FLIFTLV 428


>UniRef50_Q4RXG4 Cluster: Transporter; n=2; Euteleostomi|Rep:
           Transporter - Tetraodon nigroviridis (Green puffer)
          Length = 120

 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 33/100 (33%), Positives = 54/100 (54%), Gaps = 5/100 (5%)

Query: 457 GMYWLQLMDKYAANW-SVLIIAIGECILIAWIYGAEKFCGDIQRMIGRQSKLWVYLWSAM 515
           G Y + + D Y  +  ++L++A+ +  +I WIYG+++FC +I  MIG +      L    
Sbjct: 1   GTYIMMIFDHYVCSGPALLLLAVFQSAIIGWIYGSDRFCDNIADMIGYRPHA---LIKYS 57

Query: 516 WRIITPAALVFILVFNWIEYKPASYGH-YVYPMWADAVGW 554
           W  ITP   +  L+F  + Y P  + + YVYP W   +GW
Sbjct: 58  WMYITPLTCMGTLIFLSVRYTPIKFNNSYVYPWWGYGIGW 97


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.327    0.141    0.455 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 695,872,296
Number of Sequences: 1657284
Number of extensions: 27813359
Number of successful extensions: 81417
Number of sequences better than 10.0: 335
Number of HSP's better than 10.0 without gapping: 313
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 79836
Number of HSP's gapped (non-prelim): 739
length of query: 632
length of database: 575,637,011
effective HSP length: 105
effective length of query: 527
effective length of database: 401,622,191
effective search space: 211654894657
effective search space used: 211654894657
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.7 bits)
S2: 76 (34.7 bits)

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