Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000911-TA|BGIBMGA000911-PA|IPR013602|Dynein heavy chain,
N-terminal region 2
(560 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U53531-1|AAB09728.1| 655|Homo sapiens cytoplasmic dynein 2 heav... 254 8e-67
AB040936-1|BAA96027.2| 4464|Homo sapiens KIAA1503 protein protein. 216 2e-55
AY682080-1|AAT74625.1| 4646|Homo sapiens dynein, cytoplasmic, he... 209 2e-53
AB002323-1|BAA20783.3| 4658|Homo sapiens KIAA0325 protein protein. 209 2e-53
AB037831-1|BAA92648.2| 4355|Homo sapiens KIAA1410 protein protein. 205 3e-52
AF494040-1|AAM12861.1| 4116|Homo sapiens axonemal heavy chain dy... 186 2e-46
U53530-1|AAB09727.1| 897|Homo sapiens cytoplasmic dynein heavy ... 183 1e-45
AJ404468-1|CAB94756.1| 4486|Homo sapiens axonemal dynein heavy c... 180 2e-44
AF327442-1|AAL37427.1| 4024|Homo sapiens ciliary dynein heavy ch... 180 2e-44
AF257737-1|AAF69004.1| 4486|Homo sapiens ciliary dynein heavy ch... 180 2e-44
AB023161-1|BAA76788.2| 4031|Homo sapiens KIAA0944 protein protein. 180 2e-44
AB002355-1|BAA21573.2| 2992|Homo sapiens KIAA0357 protein. 180 2e-44
AY045575-1|AAK92217.1| 4624|Homo sapiens axonemal dynein heavy c... 176 1e-43
AK125796-1|BAC86296.1| 617|Homo sapiens protein ( Homo sapiens ... 174 6e-43
AB095937-1|BAC23113.2| 3051|Homo sapiens KIAA2017 protein protein. 174 6e-43
AL391415-3|CAI21588.1| 4695|Homo sapiens dynein, axonemal, heavy... 165 4e-40
AL391415-2|CAI21587.1| 4176|Homo sapiens dynein, axonemal, heavy... 165 4e-40
AL353700-3|CAI20294.1| 4695|Homo sapiens dynein, axonemal, heavy... 165 4e-40
AL353700-2|CAI20293.1| 4176|Homo sapiens dynein, axonemal, heavy... 165 4e-40
AL353700-1|CAI20292.1| 4490|Homo sapiens dynein, axonemal, heavy... 165 4e-40
AL035690-5|CAI19770.1| 4695|Homo sapiens dynein, axonemal, heavy... 165 4e-40
AL035690-1|CAI19769.1| 4490|Homo sapiens dynein, axonemal, heavy... 165 4e-40
AL035555-4|CAI19822.1| 4695|Homo sapiens dynein, axonemal, heavy... 165 4e-40
AL035555-3|CAI19821.1| 4176|Homo sapiens dynein, axonemal, heavy... 165 4e-40
AL035555-1|CAI19819.1| 4490|Homo sapiens dynein, axonemal, heavy... 165 4e-40
AL034345-4|CAI42436.1| 4695|Homo sapiens dynein, axonemal, heavy... 165 4e-40
AL034345-3|CAI42435.1| 4176|Homo sapiens dynein, axonemal, heavy... 165 4e-40
AL034345-1|CAI42433.1| 4490|Homo sapiens dynein, axonemal, heavy... 165 4e-40
AF356519-1|AAK60620.1| 4490|Homo sapiens axonemal dynein heavy c... 165 4e-40
AJ320497-1|CAC60121.1| 4523|Homo sapiens axonemal beta heavy cha... 163 2e-39
U20552-1|AAB50020.1| 161|Homo sapiens dynein heavy chain, isoty... 138 6e-32
Z83800-1|CAB06054.1| 179|Homo sapiens cytoplasmic dynein heavy ... 124 1e-27
AC068919-1|AAY14995.1| 2536|Homo sapiens unknown protein. 122 4e-27
AJ132083-1|CAA10556.1| 143|Homo sapiens axonemal dynein, heavy ... 120 1e-26
L23958-1|AAA16065.1| 141|Homo sapiens dynein heavy chain protein. 120 2e-26
AY049075-1|AAL06603.1| 514|Homo sapiens dynein heavy chain prot... 114 9e-25
U53532-1|AAB09729.1| 197|Homo sapiens cytoplasmic dynein 3 heav... 111 6e-24
AJ132085-1|CAA10558.1| 143|Homo sapiens axonemal dynein, heavy ... 111 6e-24
Z83805-1|CAB06059.1| 177|Homo sapiens axonemal dynein heavy cha... 101 9e-21
AJ132084-1|CAA10557.1| 143|Homo sapiens axonemal dynein, heavy ... 99 2e-20
U61737-1|AAC50701.1| 77|Homo sapiens dynein heavy chain protein. 95 8e-19
AL357912-1|CAI95150.1| 234|Homo sapiens dynein, axonemal, heavy... 92 4e-18
U61736-1|AAC50700.1| 80|Homo sapiens dynein heavy chain protein. 91 1e-17
Z83802-1|CAB06056.1| 179|Homo sapiens axonemal dynein heavy cha... 90 2e-17
U61735-1|AAC50699.1| 79|Homo sapiens dynein heavy chain protein. 87 2e-16
Z83806-1|CAB06060.1| 107|Homo sapiens axonemal dynein heavy cha... 81 1e-14
AJ132089-1|CAA10562.1| 101|Homo sapiens axonemal dynein, heavy ... 81 1e-14
U83573-1|AAB82762.1| 102|Homo sapiens axonemal dynein heavy cha... 76 3e-13
AJ132088-1|CAA10561.1| 101|Homo sapiens axonemal dynein, heavy ... 76 4e-13
AJ132086-1|CAA10559.1| 101|Homo sapiens axonemal dynein, heavy ... 75 5e-13
Z83803-1|CAB06057.1| 101|Homo sapiens axonemal dynein heavy cha... 73 2e-12
AJ132087-1|CAA10560.1| 101|Homo sapiens axonemal dynein, heavy ... 72 5e-12
U83570-1|AAB82760.1| 83|Homo sapiens axonemal dynein heavy cha... 70 2e-11
Z83801-1|CAB06055.1| 169|Homo sapiens axonemal dynein heavy cha... 69 3e-11
AC104600-1|AAY24051.1| 1270|Homo sapiens unknown protein. 68 8e-11
U61739-1|AAC50703.1| 55|Homo sapiens dynein heavy chain protein. 67 1e-10
U61738-1|AAC50702.1| 55|Homo sapiens dynein heavy chain protein. 66 2e-10
Z83799-1|CAB06053.1| 101|Homo sapiens axonemal dynein heavy cha... 66 3e-10
U61740-1|AAC50704.1| 54|Homo sapiens dynein heavy chain protein. 63 2e-09
AJ132094-1|CAB46445.1| 83|Homo sapiens axonemal dynein, heavy ... 63 2e-09
Z83804-1|CAB06058.1| 101|Homo sapiens axonemal dynein heavy cha... 61 1e-08
U83571-1|AAB82761.1| 89|Homo sapiens axonemal dynein heavy cha... 61 1e-08
U61741-1|AAC50705.1| 55|Homo sapiens dynein heavy chain protein. 57 2e-07
AJ132091-1|CAA10564.1| 57|Homo sapiens axonemal dynein, heavy ... 56 4e-07
AJ132090-1|CAA10563.1| 57|Homo sapiens axonemal dynein, heavy ... 56 4e-07
U83574-1|AAB82763.1| 50|Homo sapiens axonemal dynein heavy cha... 52 4e-06
AK074178-1|BAB85004.1| 1007|Homo sapiens FLJ00251 protein protein. 52 7e-06
AJ132093-1|CAB46444.1| 67|Homo sapiens axonemal dynein, heavy ... 44 0.001
AC005078-1|AAC78616.2| 1020|Homo sapiens Homo sapiens dynein, ax... 40 0.031
BC019878-1|AAH19878.1| 314|Homo sapiens DNAH3 protein protein. 39 0.040
U83569-1|AAB82759.1| 37|Homo sapiens axonemal dynein heavy cha... 35 0.66
AY508996-1|AAS82571.1| 1606|Homo sapiens P-Rex2 protein. 33 2.7
AJ437636-1|CAD26885.2| 1606|Homo sapiens P-Rex2 protein protein. 31 8.1
>U53531-1|AAB09728.1| 655|Homo sapiens cytoplasmic dynein 2 heavy
chain protein.
Length = 655
Score = 254 bits (621), Expect = 8e-67
Identities = 135/326 (41%), Positives = 185/326 (56%), Gaps = 16/326 (4%)
Query: 17 FQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRLGPGGMSVTALCSHF 76
F FYF+ DDDLLE+LGQ+ S V+QSHLKKLF GI V +TA+ S
Sbjct: 336 FPRFYFIGDDDLLEILGQSTNPS-----VIQSHLKKLFAGINSVCFDEKSKHITAMKSLE 390
Query: 77 GEVFQLDHPIDIDCAVEVWLKNLENEIRSSLQNMTLKCLVT--NSLHEQDPFSLPTQILC 134
GEV + + + VE WL +L E++ +L+ + +C+ T +S DP P+QILC
Sbjct: 391 GEVVPFKNKVPLSNNVETWLNDLALEMKKTLEQLLKECVTTGRSSQGAVDPSLFPSQILC 450
Query: 135 LAQNIRFTEQAERAINSKELHKFRANVEKENLYYAEAETDDENE--------RLKRQALI 186
LA+ I+FTE E AI LH+ + + Y +T E+ LK +ALI
Sbjct: 451 LAEQIKFTEDVENAIKDHSLHQIETQLVNKLEQYTNIDTSSEDPGNTESGILELKLKALI 510
Query: 187 LQCAYYLSVIKILIDNNVTSTSEWIWRKQFRFYLLNTKEVVARMGLAQIPYSYEYLGTQT 246
L + + V+K L V +T +W W+KQ RFY+ + +M ++ Y+YEY G +
Sbjct: 511 LDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRFYMKSDHTCCVQMVDSEFQYTYEYQGNAS 570
Query: 247 GQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXXXFNCDEAM 306
+ V T + D+C+L LTQA+ +G GNP+GPAGTGKTESVKA FNCDE +
Sbjct: 571 -KLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGI 629
Query: 307 DAECMGRLLTGLALSGAWGCFDEFNR 332
D + MGR+ GL GAWGCFDEFNR
Sbjct: 630 DVKSMGRIFVGLVKCGAWGCFDEFNR 655
>AB040936-1|BAA96027.2| 4464|Homo sapiens KIAA1503 protein protein.
Length = 4464
Score = 216 bits (527), Expect = 2e-55
Identities = 162/519 (31%), Positives = 248/519 (47%), Gaps = 37/519 (7%)
Query: 17 FQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRL----GPGGM-SVTA 71
F FYFLS+DDLLE+LGQ+R +Q HLKK F I +R+ GP
Sbjct: 1568 FPRFYFLSNDDLLEILGQSRNPE-----AVQPHLKKCFDNIKLLRIQKVGGPSSKWEAVG 1622
Query: 72 LCSHFGEVFQLDHPIDIDCAVEVWLKNLENEIRSSLQNMTLKC--LVTNSLHEQDPF--S 127
+ S GE H + ++ VE WL ++E +R +L+++ C + L+++D +
Sbjct: 1623 MFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDLLRNCHLALRKFLNKRDKWVKE 1682
Query: 128 LPTQILCLAQNIRFTEQAERAI-NSKE-LHKFRANVEKENLY-----YAEAETDDENE-- 178
Q++ A I++T + + +KE K V K+N Y+EA + +
Sbjct: 1683 WAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKKNQVSILNKYSEAIRGNLTKIM 1742
Query: 179 RLKRQALILQCAYYLSVIKILIDNNVTSTSEWIWRKQFRFYL-LNTKEVVARMGLAQIPY 237
RLK AL+ + V++ L + + + + W Q RFY + + V R Q Y
Sbjct: 1743 RLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRFYWEKDLDDCVIRQTNTQFQY 1802
Query: 238 SYEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXX 297
+YEYLG +G+ V T + D C++ LT ALHL G+P GPAGTGKTE+VK
Sbjct: 1803 NYEYLGN-SGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYV 1861
Query: 298 XXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRTP 357
NC E +D + MGR+ +GLA +GAWGCFDEFNR+ + L+ V HQ +LSA+
Sbjct: 1862 IVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAHQILCILSALA---- 1917
Query: 358 GTVPTASLNGKNVSVSVW-CGVAATLNPSSRGYGGXXXXXXXXXXXXXXXXXXXXXXXXX 416
+ +G +++ VW CG+ T+NP GY G
Sbjct: 1918 AGLTHFHFDGFEINL-VWSCGIFITMNP---GYAGRTELPENLKSMFRPIAMVVPDSTLI 1973
Query: 417 XXXXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYDWGLRALKXXXXXXXXXXXXXXX 476
+ + LA ++ +++LA LS Q HYD+GLRAL
Sbjct: 1974 AEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGKKRRLQPD 2033
Query: 477 XXXXXXLLAV---NNVSKLTAPDARIFHKILSLVFADVK 512
LL N++KLT+ DA +F+ I+ +F +++
Sbjct: 2034 LTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIE 2072
>AY682080-1|AAT74625.1| 4646|Homo sapiens dynein, cytoplasmic, heavy
polypeptide 1 protein.
Length = 4646
Score = 209 bits (510), Expect = 2e-53
Identities = 152/478 (31%), Positives = 220/478 (46%), Gaps = 42/478 (8%)
Query: 17 FQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRLGPGGMSVTALCSHF 76
F FYF+ D+DLLE++G ++ ++ +Q H KK+F G++ + L V + S
Sbjct: 1626 FPRFYFVGDEDLLEIIGNSKNVAK-----LQKHFKKMFAGVSSIILNEDNSVVLGISSRE 1680
Query: 77 GEVFQLDHPIDID--CAVEVWLKNLENEIRSSLQNMTLKCLVTNSLHEQ----DPFSLPT 130
GE P+ I + WL +E E+R +L + + + + + DP + T
Sbjct: 1681 GEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYIT 1740
Query: 131 -------QILCLAQNIRFTEQAERAINSK-------ELHKFRANVEKENLYYAEAETDDE 176
Q++ L+ I ++E E A++S LH +NVE A++ ++
Sbjct: 1741 WIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQ 1800
Query: 177 N--ERLKRQALILQCAYYLSVIKILIDNNVTSTSEWIWRKQFRFYL--LNT---KEVVAR 229
R K + LI + + V + LI + + + + W Q RFY T +++ +
Sbjct: 1801 PPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQ 1860
Query: 230 MGLAQIPYSYEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAX 289
M A+ Y +EYLG Q + V+T + D C+L +TQAL G+PFGPAGTGKTESVKA
Sbjct: 1861 MANAKFNYGFEYLGVQD-KLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKAL 1919
Query: 290 XXXXXXXXXXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLL 349
FNCDE D + MGR+ GL GAWGCFDEFNRL L+AV+ Q +
Sbjct: 1920 GHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQ 1979
Query: 350 SAM-THRTPG----TVP-TASLNGKNVSVSVWCGVAATLNPSSRGYGGXXXXXXXXXXXX 403
A+ H P + P T L K V VS + T+NP GY G
Sbjct: 1980 EALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNP---GYAGRSNLPDNLKKLF 2036
Query: 404 XXXXXXXXXXXXXXXXXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYDWGLRALK 461
AE LA + F L LS Q HYD+GLRALK
Sbjct: 2037 RSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALK 2094
>AB002323-1|BAA20783.3| 4658|Homo sapiens KIAA0325 protein protein.
Length = 4658
Score = 209 bits (510), Expect = 2e-53
Identities = 152/478 (31%), Positives = 220/478 (46%), Gaps = 42/478 (8%)
Query: 17 FQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRLGPGGMSVTALCSHF 76
F FYF+ D+DLLE++G ++ ++ +Q H KK+F G++ + L V + S
Sbjct: 1638 FPRFYFVGDEDLLEIIGNSKNVAK-----LQKHFKKMFAGVSSIILNEDNSVVLGISSRE 1692
Query: 77 GEVFQLDHPIDID--CAVEVWLKNLENEIRSSLQNMTLKCLVTNSLHEQ----DPFSLPT 130
GE P+ I + WL +E E+R +L + + + + + DP + T
Sbjct: 1693 GEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYIT 1752
Query: 131 -------QILCLAQNIRFTEQAERAINSK-------ELHKFRANVEKENLYYAEAETDDE 176
Q++ L+ I ++E E A++S LH +NVE A++ ++
Sbjct: 1753 WIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQ 1812
Query: 177 N--ERLKRQALILQCAYYLSVIKILIDNNVTSTSEWIWRKQFRFYL--LNT---KEVVAR 229
R K + LI + + V + LI + + + + W Q RFY T +++ +
Sbjct: 1813 PPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQ 1872
Query: 230 MGLAQIPYSYEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAX 289
M A+ Y +EYLG Q + V+T + D C+L +TQAL G+PFGPAGTGKTESVKA
Sbjct: 1873 MANAKFNYGFEYLGVQD-KLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKAL 1931
Query: 290 XXXXXXXXXXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLL 349
FNCDE D + MGR+ GL GAWGCFDEFNRL L+AV+ Q +
Sbjct: 1932 GHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQ 1991
Query: 350 SAM-THRTPG----TVP-TASLNGKNVSVSVWCGVAATLNPSSRGYGGXXXXXXXXXXXX 403
A+ H P + P T L K V VS + T+NP GY G
Sbjct: 1992 EALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNP---GYAGRSNLPDNLKKLF 2048
Query: 404 XXXXXXXXXXXXXXXXXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYDWGLRALK 461
AE LA + F L LS Q HYD+GLRALK
Sbjct: 2049 RSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALK 2106
>AB037831-1|BAA92648.2| 4355|Homo sapiens KIAA1410 protein protein.
Length = 4355
Score = 205 bits (501), Expect = 3e-52
Identities = 155/526 (29%), Positives = 229/526 (43%), Gaps = 23/526 (4%)
Query: 17 FQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRLGPGGMSVTALCSHF 76
F FYFLSDD+LLE+L Q + + +Q HL+K F I + L + +T + S
Sbjct: 1350 FPRFYFLSDDELLEILSQTKDPT-----AVQPHLRKCFENIARL-LFQEDLEITHMYSAE 1403
Query: 77 GEVFQLDHPIDIDCAVEVWLKNLENEIRSSLQNMTLKCLVTNSLHEQDPFSL--PTQILC 134
GE QL I VE WL+ +E +++S+ ++ K + + + L P Q+
Sbjct: 1404 GEEVQLCFSIYPSSNVEDWLREVERSMKASVHDIIEKAIRAYPTMPRTQWVLNWPGQVTI 1463
Query: 135 LAQNIRFTEQAERAINSKELHKFRANVEKENLYYAEAETDDENERLKR---QALILQCAY 191
+T + A+ + L + L A + R++R ALI+ +
Sbjct: 1464 AGCQTYWTMEVAEALEAGNLRSQLFPQLCQQLSDLVALVRGKLSRMQRAVLSALIVIEVH 1523
Query: 192 YLSVIKILIDNNVTSTSEWIWRKQFRFYLLNTKEVVARMGLAQIPYSYEYLGTQTGQFVR 251
V+ LI NV S +++ W Q R+Y N ++ R A+ Y YEYLG +G+ V
Sbjct: 1524 AKDVVSKLIQENVVSVNDFQWISQLRYYWTNN-DLYIRAVNAEFIYGYEYLGN-SGRLVI 1581
Query: 252 TEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXXXFNCDEAMDAECM 311
T + D C+L LT ALHL F G P GPAGTGKTE+ K FNC + +D M
Sbjct: 1582 TPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAM 1641
Query: 312 GRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRTPGTVPTASLNGKNVS 371
G+ GLA +GAW CFDEFNR+ + L+ V Q +++ A R V G +
Sbjct: 1642 GKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQKAQQQR----VERFMFEGVEIP 1697
Query: 372 VSVWCGVAATLNPSSRGYGGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLPHAER 431
+ C V T+NP GY G A
Sbjct: 1698 LVPSCAVFITMNP---GYAGRTELPDNLKALFRPVAMMVPDYAMITEISLYSFGFNEASV 1754
Query: 432 LAADLHDVFTLASALLSGQRHYDWGLRALKXXXXXXXXXXXXXXXXXXXXXLL-AVN--N 488
LA + F L+S LS Q HYD+G+RA+K L A+ N
Sbjct: 1755 LAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKRENPSMNEELICLRAIRDVN 1814
Query: 489 VSKLTAPDARIFHKILSLVFADVKDLHATADPIVNALEGSVQNLKL 534
V K D ++F I+S +F +K+ + A+ + +N L
Sbjct: 1815 VPKFLQEDLKLFSGIVSDLFPTIKEEDTDYGILDEAIREACRNSNL 1860
>AF494040-1|AAM12861.1| 4116|Homo sapiens axonemal heavy chain dynein
type 3 protein.
Length = 4116
Score = 186 bits (452), Expect = 2e-46
Identities = 140/533 (26%), Positives = 231/533 (43%), Gaps = 25/533 (4%)
Query: 12 RNALYFQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRLGPGGMSVTA 71
+ L+F F+FLS+D+LLE+L + + + +Q HLKK F GI + + +
Sbjct: 1166 KKRLFFPRFFFLSNDELLEILSETKD-----PLRVQPHLKKCFEGIAKLEF-TDNLEIVG 1219
Query: 72 LCSHFGEV---FQLDHPIDIDCAVEVWLKNLENEIRSSLQNMTLKCLVTNSLHEQDPFSL 128
+ S E Q +P + VE WL+ +E + +S++ + + ++ + L
Sbjct: 1220 MISSEKETVPFIQKIYPANAKGMVEKWLQQVEQMMLASMREVIGLGIEAYVKVPRNHWVL 1279
Query: 129 --PTQILCLAQNIRFTEQAERAINSKELHKF--RANVEKENLYYAEAETDDENERLKRQA 184
P Q++ +I +T++ +A+ L F ++N + + RL A
Sbjct: 1280 QWPGQVVICVSSIFWTQEVSQALAENTLLDFLKKSNDQIAQIVQLVRGKLSSGARLTLGA 1339
Query: 185 LILQCAYYLSVIKILIDNNVTSTSEWIWRKQFRFYLLNTKEVVARMGLAQIPYSYEYLGT 244
L + + V+ L ++ V+ +++ W Q R+Y + K+V ++ + Y YEYLG
Sbjct: 1340 LTVIDVHARDVVAKLSEDRVSDLNDFQWISQLRYYWV-AKDVQVQIITTEALYGYEYLGN 1398
Query: 245 QTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXXXFNCDE 304
+ V T + D C+ L AL L G P GPAGTGKTE+ K FNC +
Sbjct: 1399 SP-RLVITPLTDRCYRTLMGALKLNLGGAPEGPAGTGKTETTKDLAKALAKQCVVFNCSD 1457
Query: 305 AMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRTPGTVPTAS 364
+D + MG+ GLA +GAW CFDEFNR+ + L+ V Q S+ A+ + + T
Sbjct: 1458 GLDYKAMGKFFKGLAQAGAWACFDEFNRIEVEVLSVVAQQILSIQQAIIRK----LKTFI 1513
Query: 365 LNGKNVSVSVWCGVAATLNPSSRGYGGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 424
G +S++ C V T+NP GY G
Sbjct: 1514 FEGTELSLNPTCAVFITMNP---GYAGRAELPDNLKALFRTVAMMVPDYALIGEISLYSM 1570
Query: 425 SLPHAERLAADLHDVFTLASALLSGQRHYDWGLRALKXXXXXXXXXXXXXXXXXXXXXLL 484
+ LA + + L S LS Q HYD+G+RA+K LL
Sbjct: 1571 GFLDSRSLAQKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPEENESVLLL 1630
Query: 485 AV---NNVSKLTAPDARIFHKILSLVFADVKDLHATADPIVNALEGSVQNLKL 534
N++K A D +F I+S +F V + + L +++ +KL
Sbjct: 1631 RALLDVNLAKFLAQDVPLFQGIISDLFPGVVLPKPDYEVFLKVLNDNIKKMKL 1683
>U53530-1|AAB09727.1| 897|Homo sapiens cytoplasmic dynein heavy
chain 1 (DHC1) protein.
Length = 897
Score = 183 bits (446), Expect = 1e-45
Identities = 131/408 (32%), Positives = 197/408 (48%), Gaps = 42/408 (10%)
Query: 17 FQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRLGPGGMSVTALCSHF 76
F FYF+ D+DLLE++G ++ ++ +Q H KK+F G++ + L V + S
Sbjct: 497 FPRFYFVGDEDLLEIIGNSKNVAK-----LQKHFKKMFAGVSSIILNEDNSVVLGISSRE 551
Query: 77 GEVFQLDHPIDID--CAVEVWLKNLENEIRSSLQNMTLKCLVTNSLHEQ----DPFSLPT 130
GE P+ I + WL +E E+R +L + + + + + DP + T
Sbjct: 552 GEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYIT 611
Query: 131 -------QILCLAQNIRFTEQAERAINSK-------ELHKFRANVEKENLYYAEAETDDE 176
Q++ L+ I ++E E A++S +NVE A++ ++
Sbjct: 612 WIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPSDSVLSNVEVTLNVLADSVLMEQ 671
Query: 177 N--ERLKRQALILQCAYYLSVIKILIDNNVTSTSEWIWRKQFRFYL--LNT---KEVVAR 229
R K + LI + + V + LI + + + + W Q RFY T +++ +
Sbjct: 672 PPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQ 731
Query: 230 MGLAQIPYSYEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAX 289
M A+ Y +EYLG Q + V+T + D C+L +TQAL G+PFGPAGTGKTESVKA
Sbjct: 732 MANAKFNYGFEYLGVQD-KLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKAL 790
Query: 290 XXXXXXXXXXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLL 349
FNCDE D + GR+ GL GAWGCFDEFNRL L+AV+ Q +
Sbjct: 791 GHQLGRFVLVFNCDETFDFQARGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQ 850
Query: 350 SAM-THRTPG----TVP-TASLNGKNVSVSVWCGVAATLNPSSRGYGG 391
A+ H P + P T L K V VS + T+NP GY G
Sbjct: 851 EALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNP---GYAG 895
>AJ404468-1|CAB94756.1| 4486|Homo sapiens axonemal dynein heavy chain
9 protein.
Length = 4486
Score = 180 bits (437), Expect = 2e-44
Identities = 155/540 (28%), Positives = 230/540 (42%), Gaps = 34/540 (6%)
Query: 15 LYFQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRL---GPGGMSVTA 71
L F FYFLS DLL++L G+ ++V Q HL KLF + +R G + T+
Sbjct: 1599 LAFPRFYFLSSSDLLDILSN---GTAPQQV--QRHLSKLFDNMAKMRFQLDASGEPTKTS 1653
Query: 72 L--CSHFGEVFQLDHPIDIDCAVEVWLKNLENEIRSSLQNMTLKCLVT--NSLHEQDPFS 127
L S E P D VE+WL ++ +++++++ + + EQ F
Sbjct: 1654 LGMYSKEEEYVAFSEPCDCSGQVEIWLNHVLGHMKATVRHEMTEGVTAYEEKPREQWLFD 1713
Query: 128 LPTQILCLAQNIRFTEQAERAINSKELHKFRANVEKENLYYAEAET-----DDENERLKR 182
P Q+ I +T + A E A + A+ +T + + R
Sbjct: 1714 HPAQVALTCTQIWWTTEVGMAFARLEEGYESAMKDYYKKQVAQLKTLITMLIGQLSKGDR 1773
Query: 183 QALILQCA---YYLSVIKILIDNNVTSTSEWIWRKQFRF-YLLNTKEVVARMGLAQIPYS 238
Q ++ C + V+ +I V + ++W Q R + K A + AQ YS
Sbjct: 1774 QKIMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDDEVKHCFANICDAQFLYS 1833
Query: 239 YEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXX 298
YEYLG T + V T + D C++ LTQ+LHL G P GPAGTGKTE+ K
Sbjct: 1834 YEYLGN-TPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGILVY 1892
Query: 299 XFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRTPG 358
FNC E MD + G + GLA +GAWGCFDEFNR++ + L+ V Q S+ A+ +
Sbjct: 1893 VFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQVKSIQDAIRDKK-- 1950
Query: 359 TVPTASLNGKNVSVSVWCGVAATLNPSSRGYGGXXXXXXXXXXXXXXXXXXXXXXXXXXX 418
S G+ +S++ G+ T+NP GY G
Sbjct: 1951 --QWFSFLGEEISLNPSVGIFITMNP---GYAGRTELPENLKSLFRPCAMVVPDFELICE 2005
Query: 419 XXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYDWGLRALKXXXXXXXXXXXXXXXXX 478
A+ LA ++ L LLS Q HYDWGLRA+K
Sbjct: 2006 IMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPDRP 2065
Query: 479 XXXXL---LAVNNVSKLTAPDARIFHKILSLVFADVKDLHATADPIVNAL-EGSVQNLKL 534
L L N+ K+ D IF ++ +F + D+ DP AL ++ +LKL
Sbjct: 2066 EDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPAL-DVPRRRDPNFEALVRKAIVDLKL 2124
>AF327442-1|AAL37427.1| 4024|Homo sapiens ciliary dynein heavy chain 7
protein.
Length = 4024
Score = 180 bits (437), Expect = 2e-44
Identities = 149/547 (27%), Positives = 235/547 (42%), Gaps = 30/547 (5%)
Query: 12 RNALYFQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRLGPGGMSVTA 71
+ L+F F+FLS+D+LLE+L + + + +Q HLKK F GI V + +T
Sbjct: 1063 KKRLFFPRFFFLSNDELLEILSETKDPTR-----VQPHLKKCFEGIAKVEFTET-LDITH 1116
Query: 72 LCSHFGEVFQLDHPIDIDCA---VEVWLKNLENEIRSSLQNMTLKCLVTNSLHEQDPF-- 126
+ S GEV +L I A VE WL LE + +S+ +T + +E+ +
Sbjct: 1117 MKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHKVTGDATFAYTKYERINWVR 1176
Query: 127 SLPTQ-ILCLAQNIRFTEQAERAI--NSKELHKF--RANVEKENLYYAEAETDDENERLK 181
P Q +LC++Q I +T++ + AI K L ++ N + +++ R+
Sbjct: 1177 DWPGQTVLCVSQ-IFWTKEVQTAIPMGIKALEQYLKTCNRQIDDIVTLVRGKLSMQNRVT 1235
Query: 182 RQALILQCAYYLSVIKILIDNNVTSTSEWIWRKQFRFYLLNTKEVVARMGLAQIPYSYEY 241
AL++ + V+ L+ N++ S++ W Q R+Y + +M A + Y YEY
Sbjct: 1236 LGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYW-QENHLETKMINAGLRYGYEY 1294
Query: 242 LGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXXXFN 301
LG + V T + D C+ L ALHL G P GPAGTGKTE+ K FN
Sbjct: 1295 LGNSP-RLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFN 1353
Query: 302 CDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRTPGTVP 361
C + +D +G+ GL GAW CFDEFNR+ + L+ V Q ++ +
Sbjct: 1354 CSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGIN----AGAD 1409
Query: 362 TASLNGKNVSVSVWCGVAATLNPSSRGYGGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 421
G + + C V T+NP GY G
Sbjct: 1410 ILMFEGTELKLDPTCAVFITMNP---GYAGRSELPDNLKALFRTVAMMVPDYAMIAEIVL 1466
Query: 422 XXXSLPHAERLAADLHDVFTLASALLSGQRHYDWGLRALKXXXXXXXXXXXXXXXXXXXX 481
A L+ + + L S LS Q HYD+G+RA+K
Sbjct: 1467 YSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPNENEEI 1526
Query: 482 XLLAV---NNVSKLTAPDARIFHKILSLVFADVKDLHATADPIVNALEGSVQNLKLVENK 538
LL N+ K + D +F I S +F VK + ++ A++ + ++ L +
Sbjct: 1527 LLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIKDNCASMNL-QMT 1585
Query: 539 AQVSEKL 545
A SEK+
Sbjct: 1586 AFFSEKI 1592
>AF257737-1|AAF69004.1| 4486|Homo sapiens ciliary dynein heavy chain 9
protein.
Length = 4486
Score = 180 bits (437), Expect = 2e-44
Identities = 155/540 (28%), Positives = 230/540 (42%), Gaps = 34/540 (6%)
Query: 15 LYFQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRL---GPGGMSVTA 71
L F FYFLS DLL++L G+ ++V Q HL KLF + +R G + T+
Sbjct: 1599 LAFPRFYFLSSSDLLDILSN---GTAPQQV--QRHLSKLFDNMAKMRFQLDASGEPTKTS 1653
Query: 72 L--CSHFGEVFQLDHPIDIDCAVEVWLKNLENEIRSSLQNMTLKCLVT--NSLHEQDPFS 127
L S E P D VE+WL ++ +++++++ + + EQ F
Sbjct: 1654 LGMYSKEEEYVAFSEPCDCSGQVEIWLNHVLGHMKATVRHEMTEGVTAYEEKPREQWLFD 1713
Query: 128 LPTQILCLAQNIRFTEQAERAINSKELHKFRANVEKENLYYAEAET-----DDENERLKR 182
P Q+ I +T + A E A + A+ +T + + R
Sbjct: 1714 HPAQVALTCTQIWWTTEVGMAFARLEEGYESAMKDYYKKQVAQLKTLITMLIGQLSKGDR 1773
Query: 183 QALILQCA---YYLSVIKILIDNNVTSTSEWIWRKQFRF-YLLNTKEVVARMGLAQIPYS 238
Q ++ C + V+ +I V + ++W Q R + K A + AQ YS
Sbjct: 1774 QKIMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDDEVKHCFANICDAQFLYS 1833
Query: 239 YEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXX 298
YEYLG T + V T + D C++ LTQ+LHL G P GPAGTGKTE+ K
Sbjct: 1834 YEYLGN-TPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGILVY 1892
Query: 299 XFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRTPG 358
FNC E MD + G + GLA +GAWGCFDEFNR++ + L+ V Q S+ A+ +
Sbjct: 1893 VFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQVKSIQDAIRDKK-- 1950
Query: 359 TVPTASLNGKNVSVSVWCGVAATLNPSSRGYGGXXXXXXXXXXXXXXXXXXXXXXXXXXX 418
S G+ +S++ G+ T+NP GY G
Sbjct: 1951 --QWFSFLGEEISLNPSVGIFITMNP---GYAGRTELPENLKSLFRPCAMVVPDFELICE 2005
Query: 419 XXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYDWGLRALKXXXXXXXXXXXXXXXXX 478
A+ LA ++ L LLS Q HYDWGLRA+K
Sbjct: 2006 IMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPDRP 2065
Query: 479 XXXXL---LAVNNVSKLTAPDARIFHKILSLVFADVKDLHATADPIVNAL-EGSVQNLKL 534
L L N+ K+ D IF ++ +F + D+ DP AL ++ +LKL
Sbjct: 2066 EDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPAL-DVPRRRDPNFEALVRKAIVDLKL 2124
>AB023161-1|BAA76788.2| 4031|Homo sapiens KIAA0944 protein protein.
Length = 4031
Score = 180 bits (437), Expect = 2e-44
Identities = 149/547 (27%), Positives = 235/547 (42%), Gaps = 30/547 (5%)
Query: 12 RNALYFQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRLGPGGMSVTA 71
+ L+F F+FLS+D+LLE+L + + + +Q HLKK F GI V + +T
Sbjct: 1070 KKRLFFPRFFFLSNDELLEILSETKDPTR-----VQPHLKKCFEGIAKVEFTET-LDITH 1123
Query: 72 LCSHFGEVFQLDHPIDIDCA---VEVWLKNLENEIRSSLQNMTLKCLVTNSLHEQDPF-- 126
+ S GEV +L I A VE WL LE + +S+ +T + +E+ +
Sbjct: 1124 MKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHKVTGDATFAYTKYERINWVR 1183
Query: 127 SLPTQ-ILCLAQNIRFTEQAERAI--NSKELHKF--RANVEKENLYYAEAETDDENERLK 181
P Q +LC++Q I +T++ + AI K L ++ N + +++ R+
Sbjct: 1184 DWPGQTVLCVSQ-IFWTKEVQTAIPMGIKALEQYLKTCNRQIDDIVTLVRGKLSMQNRVT 1242
Query: 182 RQALILQCAYYLSVIKILIDNNVTSTSEWIWRKQFRFYLLNTKEVVARMGLAQIPYSYEY 241
AL++ + V+ L+ N++ S++ W Q R+Y + +M A + Y YEY
Sbjct: 1243 LGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYW-QENHLETKMINAGLRYGYEY 1301
Query: 242 LGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXXXFN 301
LG + V T + D C+ L ALHL G P GPAGTGKTE+ K FN
Sbjct: 1302 LGNSP-RLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFN 1360
Query: 302 CDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRTPGTVP 361
C + +D +G+ GL GAW CFDEFNR+ + L+ V Q ++ +
Sbjct: 1361 CSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGIN----AGAD 1416
Query: 362 TASLNGKNVSVSVWCGVAATLNPSSRGYGGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 421
G + + C V T+NP GY G
Sbjct: 1417 ILMFEGTELKLDPTCAVFITMNP---GYAGRSELPDNLKALFRTVAMMVPDYAMIAEIVL 1473
Query: 422 XXXSLPHAERLAADLHDVFTLASALLSGQRHYDWGLRALKXXXXXXXXXXXXXXXXXXXX 481
A L+ + + L S LS Q HYD+G+RA+K
Sbjct: 1474 YSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPNENEEI 1533
Query: 482 XLLAV---NNVSKLTAPDARIFHKILSLVFADVKDLHATADPIVNALEGSVQNLKLVENK 538
LL N+ K + D +F I S +F VK + ++ A++ + ++ L +
Sbjct: 1534 LLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIKDNCASMNL-QMT 1592
Query: 539 AQVSEKL 545
A SEK+
Sbjct: 1593 AFFSEKI 1599
>AB002355-1|BAA21573.2| 2992|Homo sapiens KIAA0357 protein.
Length = 2992
Score = 180 bits (437), Expect = 2e-44
Identities = 155/540 (28%), Positives = 230/540 (42%), Gaps = 34/540 (6%)
Query: 15 LYFQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRL---GPGGMSVTA 71
L F FYFLS DLL++L G+ ++V Q HL KLF + +R G + T+
Sbjct: 181 LAFPRFYFLSSSDLLDILSN---GTAPQQV--QRHLSKLFDNMAKMRFQLDASGEPTKTS 235
Query: 72 L--CSHFGEVFQLDHPIDIDCAVEVWLKNLENEIRSSLQNMTLKCLVT--NSLHEQDPFS 127
L S E P D VE+WL ++ +++++++ + + EQ F
Sbjct: 236 LGMYSKEEEYVAFSEPCDCSGQVEIWLNHVLGHMKATVRHEMTEGVTAYEEKPREQWLFD 295
Query: 128 LPTQILCLAQNIRFTEQAERAINSKELHKFRANVEKENLYYAEAET-----DDENERLKR 182
P Q+ I +T + A E A + A+ +T + + R
Sbjct: 296 HPAQVALTCTQIWWTTEVGMAFARLEEGYESAMKDYYKKQVAQLKTLITMLIGQLSKGDR 355
Query: 183 QALILQCA---YYLSVIKILIDNNVTSTSEWIWRKQFRF-YLLNTKEVVARMGLAQIPYS 238
Q ++ C + V+ +I V + ++W Q R + K A + AQ YS
Sbjct: 356 QKIMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDDEVKHCFANICDAQFLYS 415
Query: 239 YEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXX 298
YEYLG T + V T + D C++ LTQ+LHL G P GPAGTGKTE+ K
Sbjct: 416 YEYLGN-TPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGILVY 474
Query: 299 XFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRTPG 358
FNC E MD + G + GLA +GAWGCFDEFNR++ + L+ V Q S+ A+ +
Sbjct: 475 VFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQVKSIQDAIRDKK-- 532
Query: 359 TVPTASLNGKNVSVSVWCGVAATLNPSSRGYGGXXXXXXXXXXXXXXXXXXXXXXXXXXX 418
S G+ +S++ G+ T+NP GY G
Sbjct: 533 --QWFSFLGEEISLNPSVGIFITMNP---GYAGRTELPENLKSLFRPCAMVVPDFELICE 587
Query: 419 XXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYDWGLRALKXXXXXXXXXXXXXXXXX 478
A+ LA ++ L LLS Q HYDWGLRA+K
Sbjct: 588 IMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPDRP 647
Query: 479 XXXXL---LAVNNVSKLTAPDARIFHKILSLVFADVKDLHATADPIVNAL-EGSVQNLKL 534
L L N+ K+ D IF ++ +F + D+ DP AL ++ +LKL
Sbjct: 648 EDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPAL-DVPRRRDPNFEALVRKAIVDLKL 706
>AY045575-1|AAK92217.1| 4624|Homo sapiens axonemal dynein heavy chain
DNAH5 protein.
Length = 4624
Score = 176 bits (429), Expect = 1e-43
Identities = 143/516 (27%), Positives = 223/516 (43%), Gaps = 28/516 (5%)
Query: 12 RNALYFQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRLGPGGMS-VT 70
+ L F F+F+SD LLE+LGQA S+ + Q+HL +F I V+ +
Sbjct: 1709 KKRLCFPRFFFVSDPALLEILGQA---SDSHTI--QAHLLNVFDNIKSVKFHEKIYDRIL 1763
Query: 71 ALCSHFGEVFQLDHPIDIDCAVEVWLKNLENEIRSSLQNMTLKCL--VTNSLHEQDPF-- 126
++ S GE +LD P+ + VEVWL +L E +SSL + + + + + F
Sbjct: 1764 SISSQEGETIELDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAAANIQETGFQLTEFLS 1823
Query: 127 SLPTQILCLAQNIRFTEQAERAINSKELHKF------RANVEKENLYYAEAETD-DENER 179
S P Q+ L + +T +E A+ + + K +A +E N D ER
Sbjct: 1824 SFPAQVGLLGIQMIWTRDSEEALRNAKFDKKIMQKTNQAFLELLNTLIDVTTRDLSSTER 1883
Query: 180 LKRQALILQCAYYLSVIKILIDNNVTSTSEWIWRKQFRFYLL-NTKEVVARMGLAQIPYS 238
+K + LI + + L ++ S ++ W KQ RFY ++ +++ + Y
Sbjct: 1884 VKYETLITIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDSDKMMIHITDVAFIYQ 1943
Query: 239 YEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXX 298
E+LG T + V T + D C++ L QAL + G P GPAGTGKTE+ K
Sbjct: 1944 NEFLGC-TDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVV 2002
Query: 299 XFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRTPG 358
FNC + MD +GR+ GLA SG+WGCFDEFNR+ L+ Q S +L+
Sbjct: 2003 VFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISIILTCKKEHKKS 2062
Query: 359 TVPTASLNGKNVSVSVWCGVAATLNPSSRGYGGXXXXXXXXXXXXXXXXXXXXXXXXXXX 418
+ T +G NV+++ G+ T+NP GY G
Sbjct: 2063 FIFT---DGDNVTMNPEFGLFLTMNP---GYAGRQELPENLKINFRSVAMMVPDRQIIIR 2116
Query: 419 XXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYDWGLRALKXXXXXXXXXXXXXXXXX 478
LA ++ L LS Q HYD+GLR +
Sbjct: 2117 VKLASCGFIDNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANPMDT 2176
Query: 479 XXXXLLAV---NNVSKLTAPDARIFHKILSLVFADV 511
++ V N+SKL D +F ++ +F ++
Sbjct: 2177 ESTIVMRVLRDMNLSKLIDEDEPLFLSLIEDLFPNI 2212
>AK125796-1|BAC86296.1| 617|Homo sapiens protein ( Homo sapiens
cDNA FLJ43808 fis, clone TESTI4001148, weakly similar
to Dynein beta chain, ciliary. ).
Length = 617
Score = 174 bits (424), Expect = 6e-43
Identities = 132/465 (28%), Positives = 210/465 (45%), Gaps = 31/465 (6%)
Query: 12 RNALYFQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRLGPGGMS--- 68
RNA F F+F+SDD+LL +LG + + +Q H+ K++ I +R G
Sbjct: 45 RNA--FPRFFFISDDELLSILGSSDP------LCVQEHMIKMYDNIASLRFNDGDSGEKL 96
Query: 69 VTALCSHFGEVFQLDHPIDIDCAVEVWLKNLENEIRSSLQNMTLKCLVT--NSLHEQDPF 126
V+A+ S GEV + + + VE W+ + NE+R + + +T + + D
Sbjct: 97 VSAMISAEGEVMEFRKIVRAEGRVEDWMTAVLNEMRRTNRLITKEAIFRYCEDRSRVDWM 156
Query: 127 SLPTQILCLAQN-IRFTEQAERAINSKELHKFRANVE---KENLYYAEAETD-----DEN 177
L ++ LA + + +T + E + + + +A K + E T +N
Sbjct: 157 LLYQGMVVLAASQVWWTWEVEDVFHKAQKGEKQAMKNYGRKMHRQIDELVTRITMPLSKN 216
Query: 178 ERLKRQALILQCAYYLSVIKILIDNNVTSTSEWIWRKQFRFYL-LNTKEVVARMGLAQIP 236
+R K +++ + ++ I ++ E+ W Q RFY E+ R
Sbjct: 217 DRKKYNTVLIIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDREPDELNIRQCTGTFG 276
Query: 237 YSYEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXX 296
Y YEY+G G+ V T + D +L LTQAL + G P GPAGTGKTE+ K
Sbjct: 277 YGYEYMGLN-GRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLL 335
Query: 297 XXXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRT 356
NC E MD +G++ +GLA GAWGCFDEFNR+ + L+ ++ Q ++ +A+ H+
Sbjct: 336 CVVTNCGEGMDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQ- 394
Query: 357 PGTVPTASLNGKNVSVSVWCGVAATLNPSSRGYGGXXXXXXXXXXXXXXXXXXXXXXXXX 416
+ T G+ +S+ G+ T+NP GY G
Sbjct: 395 ---LTTFQFEGQEISLDSRMGIFITMNP---GYAGRTELPESVKALFRPVVVIVPDLQQI 448
Query: 417 XXXXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYDWGLRALK 461
A+ LA + ++ LA LS Q HYD+GLRALK
Sbjct: 449 CEIMLFSEGFLEAKTLAKKMTVLYKLAREQLSKQYHYDFGLRALK 493
>AB095937-1|BAC23113.2| 3051|Homo sapiens KIAA2017 protein protein.
Length = 3051
Score = 174 bits (424), Expect = 6e-43
Identities = 132/465 (28%), Positives = 210/465 (45%), Gaps = 31/465 (6%)
Query: 12 RNALYFQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRLGPGGMS--- 68
RNA F F+F+SDD+LL +LG + + +Q H+ K++ I +R G
Sbjct: 142 RNA--FPRFFFISDDELLSILGSSDP------LCVQEHMIKMYDNIASLRFNDGDSGEKL 193
Query: 69 VTALCSHFGEVFQLDHPIDIDCAVEVWLKNLENEIRSSLQNMTLKCLVT--NSLHEQDPF 126
V+A+ S GEV + + + VE W+ + NE+R + + +T + + D
Sbjct: 194 VSAMISAEGEVMEFRKIVRAEGRVEDWMTAVLNEMRRTNRLITKEAIFRYCEDRSRVDWM 253
Query: 127 SLPTQILCLAQN-IRFTEQAERAINSKELHKFRANVE---KENLYYAEAETD-----DEN 177
L ++ LA + + +T + E + + + +A K + E T +N
Sbjct: 254 LLYQGMVVLAASQVWWTWEVEDVFHKAQKGEKQAMKNYGRKMHRQIDELVTRITMPLSKN 313
Query: 178 ERLKRQALILQCAYYLSVIKILIDNNVTSTSEWIWRKQFRFYL-LNTKEVVARMGLAQIP 236
+R K +++ + ++ I ++ E+ W Q RFY E+ R
Sbjct: 314 DRKKYNTVLIIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDREPDELNIRQCTGTFG 373
Query: 237 YSYEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXX 296
Y YEY+G G+ V T + D +L LTQAL + G P GPAGTGKTE+ K
Sbjct: 374 YGYEYMGLN-GRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLL 432
Query: 297 XXXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRT 356
NC E MD +G++ +GLA GAWGCFDEFNR+ + L+ ++ Q ++ +A+ H+
Sbjct: 433 CVVTNCGEGMDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQ- 491
Query: 357 PGTVPTASLNGKNVSVSVWCGVAATLNPSSRGYGGXXXXXXXXXXXXXXXXXXXXXXXXX 416
+ T G+ +S+ G+ T+NP GY G
Sbjct: 492 ---LTTFQFEGQEISLDSRMGIFITMNP---GYAGRTELPESVKALFRPVVVIVPDLQQI 545
Query: 417 XXXXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYDWGLRALK 461
A+ LA + ++ LA LS Q HYD+GLRALK
Sbjct: 546 CEIMLFSEGFLEAKTLAKKMTVLYKLAREQLSKQYHYDFGLRALK 590
>AL391415-3|CAI21588.1| 4695|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4695
Score = 165 bits (401), Expect = 4e-40
Identities = 145/535 (27%), Positives = 228/535 (42%), Gaps = 28/535 (5%)
Query: 12 RNALYFQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRLGPGGMS-VT 70
+ L F F+F+SD LLE+LGQA S+ + Q HL + I V +
Sbjct: 1780 KKRLLFPRFFFVSDPVLLEILGQA---SDSHTI--QPHLPAVSDNINEVTFHAKDYDRIM 1834
Query: 71 ALCSHFGEVFQLDHPIDIDCAVEVWLKNLENEIRSSLQNMTLKCL--VTNSLHEQDPF-- 126
A+ S GE LD+ + VE+WL +L SSL N+ +++S + PF
Sbjct: 1835 AVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLS 1894
Query: 127 SLPTQILCLAQNIRFTEQAERAI-NSKELHKFRANVEKE-----NLYYAEAETD-DENER 179
P Q+ L + +T +E A+ N+K+ K ++ N ++ D + +R
Sbjct: 1895 HFPAQVGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDR 1954
Query: 180 LKRQALILQCAYYLSVIKILIDNNVTSTSEWIWRKQFRFYLL-NTKEVVARMGLAQIPYS 238
+K + LI + + L+ ++ S +++ W KQ RFY + + V + Y
Sbjct: 1955 VKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQ 2014
Query: 239 YEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXX 298
E+LG T + V T + D C++ L QAL + G P GPAGTGKTE+ K
Sbjct: 2015 NEFLGC-TDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVV 2073
Query: 299 XFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRTPG 358
FNC + MD +GR+ GLA SG+WGCFDEFNR+ L+ Q +L+A R
Sbjct: 2074 VFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQ 2133
Query: 359 TVPTASLNGKNVSVSVWCGVAATLNPSSRGYGGXXXXXXXXXXXXXXXXXXXXXXXXXXX 418
+ + +G V ++ G+ T+NP GY G
Sbjct: 2134 FIFS---DGDCVDLNPEFGIFLTMNP---GYAGRQELPENLKIQFRTVAMMVPDRQIIMR 2187
Query: 419 XXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYDWGLRALKXXXXXXXXXXXXXXXXX 478
LA + ++ L L+ Q HYD+GLR +
Sbjct: 2188 VKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDS 2247
Query: 479 XXXXL---LAVNNVSKLTAPDARIFHKILSLVFADVKDLHATADPIVNALEGSVQ 530
+ L N+SKL D +F +++ +F ++ T + NA+ VQ
Sbjct: 2248 ELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQ 2302
>AL391415-2|CAI21587.1| 4176|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4176
Score = 165 bits (401), Expect = 4e-40
Identities = 145/535 (27%), Positives = 228/535 (42%), Gaps = 28/535 (5%)
Query: 12 RNALYFQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRLGPGGMS-VT 70
+ L F F+F+SD LLE+LGQA S+ + Q HL + I V +
Sbjct: 1780 KKRLLFPRFFFVSDPVLLEILGQA---SDSHTI--QPHLPAVSDNINEVTFHAKDYDRIM 1834
Query: 71 ALCSHFGEVFQLDHPIDIDCAVEVWLKNLENEIRSSLQNMTLKCL--VTNSLHEQDPF-- 126
A+ S GE LD+ + VE+WL +L SSL N+ +++S + PF
Sbjct: 1835 AVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLS 1894
Query: 127 SLPTQILCLAQNIRFTEQAERAI-NSKELHKFRANVEKE-----NLYYAEAETD-DENER 179
P Q+ L + +T +E A+ N+K+ K ++ N ++ D + +R
Sbjct: 1895 HFPAQVGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDR 1954
Query: 180 LKRQALILQCAYYLSVIKILIDNNVTSTSEWIWRKQFRFYLL-NTKEVVARMGLAQIPYS 238
+K + LI + + L+ ++ S +++ W KQ RFY + + V + Y
Sbjct: 1955 VKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQ 2014
Query: 239 YEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXX 298
E+LG T + V T + D C++ L QAL + G P GPAGTGKTE+ K
Sbjct: 2015 NEFLGC-TDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVV 2073
Query: 299 XFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRTPG 358
FNC + MD +GR+ GLA SG+WGCFDEFNR+ L+ Q +L+A R
Sbjct: 2074 VFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQ 2133
Query: 359 TVPTASLNGKNVSVSVWCGVAATLNPSSRGYGGXXXXXXXXXXXXXXXXXXXXXXXXXXX 418
+ + +G V ++ G+ T+NP GY G
Sbjct: 2134 FIFS---DGDCVDLNPEFGIFLTMNP---GYAGRQELPENLKIQFRTVAMMVPDRQIIMR 2187
Query: 419 XXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYDWGLRALKXXXXXXXXXXXXXXXXX 478
LA + ++ L L+ Q HYD+GLR +
Sbjct: 2188 VKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDS 2247
Query: 479 XXXXL---LAVNNVSKLTAPDARIFHKILSLVFADVKDLHATADPIVNALEGSVQ 530
+ L N+SKL D +F +++ +F ++ T + NA+ VQ
Sbjct: 2248 ELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQ 2302
>AL353700-3|CAI20294.1| 4695|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4695
Score = 165 bits (401), Expect = 4e-40
Identities = 145/535 (27%), Positives = 228/535 (42%), Gaps = 28/535 (5%)
Query: 12 RNALYFQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRLGPGGMS-VT 70
+ L F F+F+SD LLE+LGQA S+ + Q HL + I V +
Sbjct: 1780 KKRLLFPRFFFVSDPVLLEILGQA---SDSHTI--QPHLPAVSDNINEVTFHAKDYDRIM 1834
Query: 71 ALCSHFGEVFQLDHPIDIDCAVEVWLKNLENEIRSSLQNMTLKCL--VTNSLHEQDPF-- 126
A+ S GE LD+ + VE+WL +L SSL N+ +++S + PF
Sbjct: 1835 AVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLS 1894
Query: 127 SLPTQILCLAQNIRFTEQAERAI-NSKELHKFRANVEKE-----NLYYAEAETD-DENER 179
P Q+ L + +T +E A+ N+K+ K ++ N ++ D + +R
Sbjct: 1895 HFPAQVGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDR 1954
Query: 180 LKRQALILQCAYYLSVIKILIDNNVTSTSEWIWRKQFRFYLL-NTKEVVARMGLAQIPYS 238
+K + LI + + L+ ++ S +++ W KQ RFY + + V + Y
Sbjct: 1955 VKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQ 2014
Query: 239 YEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXX 298
E+LG T + V T + D C++ L QAL + G P GPAGTGKTE+ K
Sbjct: 2015 NEFLGC-TDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVV 2073
Query: 299 XFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRTPG 358
FNC + MD +GR+ GLA SG+WGCFDEFNR+ L+ Q +L+A R
Sbjct: 2074 VFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQ 2133
Query: 359 TVPTASLNGKNVSVSVWCGVAATLNPSSRGYGGXXXXXXXXXXXXXXXXXXXXXXXXXXX 418
+ + +G V ++ G+ T+NP GY G
Sbjct: 2134 FIFS---DGDCVDLNPEFGIFLTMNP---GYAGRQELPENLKIQFRTVAMMVPDRQIIMR 2187
Query: 419 XXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYDWGLRALKXXXXXXXXXXXXXXXXX 478
LA + ++ L L+ Q HYD+GLR +
Sbjct: 2188 VKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDS 2247
Query: 479 XXXXL---LAVNNVSKLTAPDARIFHKILSLVFADVKDLHATADPIVNALEGSVQ 530
+ L N+SKL D +F +++ +F ++ T + NA+ VQ
Sbjct: 2248 ELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQ 2302
>AL353700-2|CAI20293.1| 4176|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4176
Score = 165 bits (401), Expect = 4e-40
Identities = 145/535 (27%), Positives = 228/535 (42%), Gaps = 28/535 (5%)
Query: 12 RNALYFQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRLGPGGMS-VT 70
+ L F F+F+SD LLE+LGQA S+ + Q HL + I V +
Sbjct: 1780 KKRLLFPRFFFVSDPVLLEILGQA---SDSHTI--QPHLPAVSDNINEVTFHAKDYDRIM 1834
Query: 71 ALCSHFGEVFQLDHPIDIDCAVEVWLKNLENEIRSSLQNMTLKCL--VTNSLHEQDPF-- 126
A+ S GE LD+ + VE+WL +L SSL N+ +++S + PF
Sbjct: 1835 AVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLS 1894
Query: 127 SLPTQILCLAQNIRFTEQAERAI-NSKELHKFRANVEKE-----NLYYAEAETD-DENER 179
P Q+ L + +T +E A+ N+K+ K ++ N ++ D + +R
Sbjct: 1895 HFPAQVGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDR 1954
Query: 180 LKRQALILQCAYYLSVIKILIDNNVTSTSEWIWRKQFRFYLL-NTKEVVARMGLAQIPYS 238
+K + LI + + L+ ++ S +++ W KQ RFY + + V + Y
Sbjct: 1955 VKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQ 2014
Query: 239 YEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXX 298
E+LG T + V T + D C++ L QAL + G P GPAGTGKTE+ K
Sbjct: 2015 NEFLGC-TDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVV 2073
Query: 299 XFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRTPG 358
FNC + MD +GR+ GLA SG+WGCFDEFNR+ L+ Q +L+A R
Sbjct: 2074 VFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQ 2133
Query: 359 TVPTASLNGKNVSVSVWCGVAATLNPSSRGYGGXXXXXXXXXXXXXXXXXXXXXXXXXXX 418
+ + +G V ++ G+ T+NP GY G
Sbjct: 2134 FIFS---DGDCVDLNPEFGIFLTMNP---GYAGRQELPENLKIQFRTVAMMVPDRQIIMR 2187
Query: 419 XXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYDWGLRALKXXXXXXXXXXXXXXXXX 478
LA + ++ L L+ Q HYD+GLR +
Sbjct: 2188 VKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDS 2247
Query: 479 XXXXL---LAVNNVSKLTAPDARIFHKILSLVFADVKDLHATADPIVNALEGSVQ 530
+ L N+SKL D +F +++ +F ++ T + NA+ VQ
Sbjct: 2248 ELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQ 2302
>AL353700-1|CAI20292.1| 4490|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4490
Score = 165 bits (401), Expect = 4e-40
Identities = 145/535 (27%), Positives = 228/535 (42%), Gaps = 28/535 (5%)
Query: 12 RNALYFQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRLGPGGMS-VT 70
+ L F F+F+SD LLE+LGQA S+ + Q HL + I V +
Sbjct: 1575 KKRLLFPRFFFVSDPVLLEILGQA---SDSHTI--QPHLPAVSDNINEVTFHAKDYDRIM 1629
Query: 71 ALCSHFGEVFQLDHPIDIDCAVEVWLKNLENEIRSSLQNMTLKCL--VTNSLHEQDPF-- 126
A+ S GE LD+ + VE+WL +L SSL N+ +++S + PF
Sbjct: 1630 AVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLS 1689
Query: 127 SLPTQILCLAQNIRFTEQAERAI-NSKELHKFRANVEKE-----NLYYAEAETD-DENER 179
P Q+ L + +T +E A+ N+K+ K ++ N ++ D + +R
Sbjct: 1690 HFPAQVGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDR 1749
Query: 180 LKRQALILQCAYYLSVIKILIDNNVTSTSEWIWRKQFRFYLL-NTKEVVARMGLAQIPYS 238
+K + LI + + L+ ++ S +++ W KQ RFY + + V + Y
Sbjct: 1750 VKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQ 1809
Query: 239 YEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXX 298
E+LG T + V T + D C++ L QAL + G P GPAGTGKTE+ K
Sbjct: 1810 NEFLGC-TDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVV 1868
Query: 299 XFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRTPG 358
FNC + MD +GR+ GLA SG+WGCFDEFNR+ L+ Q +L+A R
Sbjct: 1869 VFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQ 1928
Query: 359 TVPTASLNGKNVSVSVWCGVAATLNPSSRGYGGXXXXXXXXXXXXXXXXXXXXXXXXXXX 418
+ + +G V ++ G+ T+NP GY G
Sbjct: 1929 FIFS---DGDCVDLNPEFGIFLTMNP---GYAGRQELPENLKIQFRTVAMMVPDRQIIMR 1982
Query: 419 XXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYDWGLRALKXXXXXXXXXXXXXXXXX 478
LA + ++ L L+ Q HYD+GLR +
Sbjct: 1983 VKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDS 2042
Query: 479 XXXXL---LAVNNVSKLTAPDARIFHKILSLVFADVKDLHATADPIVNALEGSVQ 530
+ L N+SKL D +F +++ +F ++ T + NA+ VQ
Sbjct: 2043 ELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQ 2097
>AL035690-5|CAI19770.1| 4695|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4695
Score = 165 bits (401), Expect = 4e-40
Identities = 145/535 (27%), Positives = 228/535 (42%), Gaps = 28/535 (5%)
Query: 12 RNALYFQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRLGPGGMS-VT 70
+ L F F+F+SD LLE+LGQA S+ + Q HL + I V +
Sbjct: 1780 KKRLLFPRFFFVSDPVLLEILGQA---SDSHTI--QPHLPAVSDNINEVTFHAKDYDRIM 1834
Query: 71 ALCSHFGEVFQLDHPIDIDCAVEVWLKNLENEIRSSLQNMTLKCL--VTNSLHEQDPF-- 126
A+ S GE LD+ + VE+WL +L SSL N+ +++S + PF
Sbjct: 1835 AVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLS 1894
Query: 127 SLPTQILCLAQNIRFTEQAERAI-NSKELHKFRANVEKE-----NLYYAEAETD-DENER 179
P Q+ L + +T +E A+ N+K+ K ++ N ++ D + +R
Sbjct: 1895 HFPAQVGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDR 1954
Query: 180 LKRQALILQCAYYLSVIKILIDNNVTSTSEWIWRKQFRFYLL-NTKEVVARMGLAQIPYS 238
+K + LI + + L+ ++ S +++ W KQ RFY + + V + Y
Sbjct: 1955 VKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQ 2014
Query: 239 YEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXX 298
E+LG T + V T + D C++ L QAL + G P GPAGTGKTE+ K
Sbjct: 2015 NEFLGC-TDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVV 2073
Query: 299 XFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRTPG 358
FNC + MD +GR+ GLA SG+WGCFDEFNR+ L+ Q +L+A R
Sbjct: 2074 VFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQ 2133
Query: 359 TVPTASLNGKNVSVSVWCGVAATLNPSSRGYGGXXXXXXXXXXXXXXXXXXXXXXXXXXX 418
+ + +G V ++ G+ T+NP GY G
Sbjct: 2134 FIFS---DGDCVDLNPEFGIFLTMNP---GYAGRQELPENLKIQFRTVAMMVPDRQIIMR 2187
Query: 419 XXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYDWGLRALKXXXXXXXXXXXXXXXXX 478
LA + ++ L L+ Q HYD+GLR +
Sbjct: 2188 VKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDS 2247
Query: 479 XXXXL---LAVNNVSKLTAPDARIFHKILSLVFADVKDLHATADPIVNALEGSVQ 530
+ L N+SKL D +F +++ +F ++ T + NA+ VQ
Sbjct: 2248 ELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQ 2302
>AL035690-1|CAI19769.1| 4490|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4490
Score = 165 bits (401), Expect = 4e-40
Identities = 145/535 (27%), Positives = 228/535 (42%), Gaps = 28/535 (5%)
Query: 12 RNALYFQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRLGPGGMS-VT 70
+ L F F+F+SD LLE+LGQA S+ + Q HL + I V +
Sbjct: 1575 KKRLLFPRFFFVSDPVLLEILGQA---SDSHTI--QPHLPAVSDNINEVTFHAKDYDRIM 1629
Query: 71 ALCSHFGEVFQLDHPIDIDCAVEVWLKNLENEIRSSLQNMTLKCL--VTNSLHEQDPF-- 126
A+ S GE LD+ + VE+WL +L SSL N+ +++S + PF
Sbjct: 1630 AVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLS 1689
Query: 127 SLPTQILCLAQNIRFTEQAERAI-NSKELHKFRANVEKE-----NLYYAEAETD-DENER 179
P Q+ L + +T +E A+ N+K+ K ++ N ++ D + +R
Sbjct: 1690 HFPAQVGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDR 1749
Query: 180 LKRQALILQCAYYLSVIKILIDNNVTSTSEWIWRKQFRFYLL-NTKEVVARMGLAQIPYS 238
+K + LI + + L+ ++ S +++ W KQ RFY + + V + Y
Sbjct: 1750 VKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQ 1809
Query: 239 YEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXX 298
E+LG T + V T + D C++ L QAL + G P GPAGTGKTE+ K
Sbjct: 1810 NEFLGC-TDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVV 1868
Query: 299 XFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRTPG 358
FNC + MD +GR+ GLA SG+WGCFDEFNR+ L+ Q +L+A R
Sbjct: 1869 VFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQ 1928
Query: 359 TVPTASLNGKNVSVSVWCGVAATLNPSSRGYGGXXXXXXXXXXXXXXXXXXXXXXXXXXX 418
+ + +G V ++ G+ T+NP GY G
Sbjct: 1929 FIFS---DGDCVDLNPEFGIFLTMNP---GYAGRQELPENLKIQFRTVAMMVPDRQIIMR 1982
Query: 419 XXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYDWGLRALKXXXXXXXXXXXXXXXXX 478
LA + ++ L L+ Q HYD+GLR +
Sbjct: 1983 VKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDS 2042
Query: 479 XXXXL---LAVNNVSKLTAPDARIFHKILSLVFADVKDLHATADPIVNALEGSVQ 530
+ L N+SKL D +F +++ +F ++ T + NA+ VQ
Sbjct: 2043 ELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQ 2097
>AL035555-4|CAI19822.1| 4695|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4695
Score = 165 bits (401), Expect = 4e-40
Identities = 145/535 (27%), Positives = 228/535 (42%), Gaps = 28/535 (5%)
Query: 12 RNALYFQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRLGPGGMS-VT 70
+ L F F+F+SD LLE+LGQA S+ + Q HL + I V +
Sbjct: 1780 KKRLLFPRFFFVSDPVLLEILGQA---SDSHTI--QPHLPAVSDNINEVTFHAKDYDRIM 1834
Query: 71 ALCSHFGEVFQLDHPIDIDCAVEVWLKNLENEIRSSLQNMTLKCL--VTNSLHEQDPF-- 126
A+ S GE LD+ + VE+WL +L SSL N+ +++S + PF
Sbjct: 1835 AVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLS 1894
Query: 127 SLPTQILCLAQNIRFTEQAERAI-NSKELHKFRANVEKE-----NLYYAEAETD-DENER 179
P Q+ L + +T +E A+ N+K+ K ++ N ++ D + +R
Sbjct: 1895 HFPAQVGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDR 1954
Query: 180 LKRQALILQCAYYLSVIKILIDNNVTSTSEWIWRKQFRFYLL-NTKEVVARMGLAQIPYS 238
+K + LI + + L+ ++ S +++ W KQ RFY + + V + Y
Sbjct: 1955 VKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQ 2014
Query: 239 YEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXX 298
E+LG T + V T + D C++ L QAL + G P GPAGTGKTE+ K
Sbjct: 2015 NEFLGC-TDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVV 2073
Query: 299 XFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRTPG 358
FNC + MD +GR+ GLA SG+WGCFDEFNR+ L+ Q +L+A R
Sbjct: 2074 VFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQ 2133
Query: 359 TVPTASLNGKNVSVSVWCGVAATLNPSSRGYGGXXXXXXXXXXXXXXXXXXXXXXXXXXX 418
+ + +G V ++ G+ T+NP GY G
Sbjct: 2134 FIFS---DGDCVDLNPEFGIFLTMNP---GYAGRQELPENLKIQFRTVAMMVPDRQIIMR 2187
Query: 419 XXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYDWGLRALKXXXXXXXXXXXXXXXXX 478
LA + ++ L L+ Q HYD+GLR +
Sbjct: 2188 VKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDS 2247
Query: 479 XXXXL---LAVNNVSKLTAPDARIFHKILSLVFADVKDLHATADPIVNALEGSVQ 530
+ L N+SKL D +F +++ +F ++ T + NA+ VQ
Sbjct: 2248 ELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQ 2302
>AL035555-3|CAI19821.1| 4176|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4176
Score = 165 bits (401), Expect = 4e-40
Identities = 145/535 (27%), Positives = 228/535 (42%), Gaps = 28/535 (5%)
Query: 12 RNALYFQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRLGPGGMS-VT 70
+ L F F+F+SD LLE+LGQA S+ + Q HL + I V +
Sbjct: 1780 KKRLLFPRFFFVSDPVLLEILGQA---SDSHTI--QPHLPAVSDNINEVTFHAKDYDRIM 1834
Query: 71 ALCSHFGEVFQLDHPIDIDCAVEVWLKNLENEIRSSLQNMTLKCL--VTNSLHEQDPF-- 126
A+ S GE LD+ + VE+WL +L SSL N+ +++S + PF
Sbjct: 1835 AVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLS 1894
Query: 127 SLPTQILCLAQNIRFTEQAERAI-NSKELHKFRANVEKE-----NLYYAEAETD-DENER 179
P Q+ L + +T +E A+ N+K+ K ++ N ++ D + +R
Sbjct: 1895 HFPAQVGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDR 1954
Query: 180 LKRQALILQCAYYLSVIKILIDNNVTSTSEWIWRKQFRFYLL-NTKEVVARMGLAQIPYS 238
+K + LI + + L+ ++ S +++ W KQ RFY + + V + Y
Sbjct: 1955 VKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQ 2014
Query: 239 YEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXX 298
E+LG T + V T + D C++ L QAL + G P GPAGTGKTE+ K
Sbjct: 2015 NEFLGC-TDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVV 2073
Query: 299 XFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRTPG 358
FNC + MD +GR+ GLA SG+WGCFDEFNR+ L+ Q +L+A R
Sbjct: 2074 VFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQ 2133
Query: 359 TVPTASLNGKNVSVSVWCGVAATLNPSSRGYGGXXXXXXXXXXXXXXXXXXXXXXXXXXX 418
+ + +G V ++ G+ T+NP GY G
Sbjct: 2134 FIFS---DGDCVDLNPEFGIFLTMNP---GYAGRQELPENLKIQFRTVAMMVPDRQIIMR 2187
Query: 419 XXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYDWGLRALKXXXXXXXXXXXXXXXXX 478
LA + ++ L L+ Q HYD+GLR +
Sbjct: 2188 VKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDS 2247
Query: 479 XXXXL---LAVNNVSKLTAPDARIFHKILSLVFADVKDLHATADPIVNALEGSVQ 530
+ L N+SKL D +F +++ +F ++ T + NA+ VQ
Sbjct: 2248 ELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQ 2302
>AL035555-1|CAI19819.1| 4490|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4490
Score = 165 bits (401), Expect = 4e-40
Identities = 145/535 (27%), Positives = 228/535 (42%), Gaps = 28/535 (5%)
Query: 12 RNALYFQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRLGPGGMS-VT 70
+ L F F+F+SD LLE+LGQA S+ + Q HL + I V +
Sbjct: 1575 KKRLLFPRFFFVSDPVLLEILGQA---SDSHTI--QPHLPAVSDNINEVTFHAKDYDRIM 1629
Query: 71 ALCSHFGEVFQLDHPIDIDCAVEVWLKNLENEIRSSLQNMTLKCL--VTNSLHEQDPF-- 126
A+ S GE LD+ + VE+WL +L SSL N+ +++S + PF
Sbjct: 1630 AVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLS 1689
Query: 127 SLPTQILCLAQNIRFTEQAERAI-NSKELHKFRANVEKE-----NLYYAEAETD-DENER 179
P Q+ L + +T +E A+ N+K+ K ++ N ++ D + +R
Sbjct: 1690 HFPAQVGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDR 1749
Query: 180 LKRQALILQCAYYLSVIKILIDNNVTSTSEWIWRKQFRFYLL-NTKEVVARMGLAQIPYS 238
+K + LI + + L+ ++ S +++ W KQ RFY + + V + Y
Sbjct: 1750 VKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQ 1809
Query: 239 YEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXX 298
E+LG T + V T + D C++ L QAL + G P GPAGTGKTE+ K
Sbjct: 1810 NEFLGC-TDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVV 1868
Query: 299 XFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRTPG 358
FNC + MD +GR+ GLA SG+WGCFDEFNR+ L+ Q +L+A R
Sbjct: 1869 VFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQ 1928
Query: 359 TVPTASLNGKNVSVSVWCGVAATLNPSSRGYGGXXXXXXXXXXXXXXXXXXXXXXXXXXX 418
+ + +G V ++ G+ T+NP GY G
Sbjct: 1929 FIFS---DGDCVDLNPEFGIFLTMNP---GYAGRQELPENLKIQFRTVAMMVPDRQIIMR 1982
Query: 419 XXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYDWGLRALKXXXXXXXXXXXXXXXXX 478
LA + ++ L L+ Q HYD+GLR +
Sbjct: 1983 VKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDS 2042
Query: 479 XXXXL---LAVNNVSKLTAPDARIFHKILSLVFADVKDLHATADPIVNALEGSVQ 530
+ L N+SKL D +F +++ +F ++ T + NA+ VQ
Sbjct: 2043 ELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQ 2097
>AL034345-4|CAI42436.1| 4695|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4695
Score = 165 bits (401), Expect = 4e-40
Identities = 145/535 (27%), Positives = 228/535 (42%), Gaps = 28/535 (5%)
Query: 12 RNALYFQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRLGPGGMS-VT 70
+ L F F+F+SD LLE+LGQA S+ + Q HL + I V +
Sbjct: 1780 KKRLLFPRFFFVSDPVLLEILGQA---SDSHTI--QPHLPAVSDNINEVTFHAKDYDRIM 1834
Query: 71 ALCSHFGEVFQLDHPIDIDCAVEVWLKNLENEIRSSLQNMTLKCL--VTNSLHEQDPF-- 126
A+ S GE LD+ + VE+WL +L SSL N+ +++S + PF
Sbjct: 1835 AVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLS 1894
Query: 127 SLPTQILCLAQNIRFTEQAERAI-NSKELHKFRANVEKE-----NLYYAEAETD-DENER 179
P Q+ L + +T +E A+ N+K+ K ++ N ++ D + +R
Sbjct: 1895 HFPAQVGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDR 1954
Query: 180 LKRQALILQCAYYLSVIKILIDNNVTSTSEWIWRKQFRFYLL-NTKEVVARMGLAQIPYS 238
+K + LI + + L+ ++ S +++ W KQ RFY + + V + Y
Sbjct: 1955 VKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQ 2014
Query: 239 YEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXX 298
E+LG T + V T + D C++ L QAL + G P GPAGTGKTE+ K
Sbjct: 2015 NEFLGC-TDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVV 2073
Query: 299 XFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRTPG 358
FNC + MD +GR+ GLA SG+WGCFDEFNR+ L+ Q +L+A R
Sbjct: 2074 VFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQ 2133
Query: 359 TVPTASLNGKNVSVSVWCGVAATLNPSSRGYGGXXXXXXXXXXXXXXXXXXXXXXXXXXX 418
+ + +G V ++ G+ T+NP GY G
Sbjct: 2134 FIFS---DGDCVDLNPEFGIFLTMNP---GYAGRQELPENLKIQFRTVAMMVPDRQIIMR 2187
Query: 419 XXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYDWGLRALKXXXXXXXXXXXXXXXXX 478
LA + ++ L L+ Q HYD+GLR +
Sbjct: 2188 VKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDS 2247
Query: 479 XXXXL---LAVNNVSKLTAPDARIFHKILSLVFADVKDLHATADPIVNALEGSVQ 530
+ L N+SKL D +F +++ +F ++ T + NA+ VQ
Sbjct: 2248 ELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQ 2302
>AL034345-3|CAI42435.1| 4176|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4176
Score = 165 bits (401), Expect = 4e-40
Identities = 145/535 (27%), Positives = 228/535 (42%), Gaps = 28/535 (5%)
Query: 12 RNALYFQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRLGPGGMS-VT 70
+ L F F+F+SD LLE+LGQA S+ + Q HL + I V +
Sbjct: 1780 KKRLLFPRFFFVSDPVLLEILGQA---SDSHTI--QPHLPAVSDNINEVTFHAKDYDRIM 1834
Query: 71 ALCSHFGEVFQLDHPIDIDCAVEVWLKNLENEIRSSLQNMTLKCL--VTNSLHEQDPF-- 126
A+ S GE LD+ + VE+WL +L SSL N+ +++S + PF
Sbjct: 1835 AVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLS 1894
Query: 127 SLPTQILCLAQNIRFTEQAERAI-NSKELHKFRANVEKE-----NLYYAEAETD-DENER 179
P Q+ L + +T +E A+ N+K+ K ++ N ++ D + +R
Sbjct: 1895 HFPAQVGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDR 1954
Query: 180 LKRQALILQCAYYLSVIKILIDNNVTSTSEWIWRKQFRFYLL-NTKEVVARMGLAQIPYS 238
+K + LI + + L+ ++ S +++ W KQ RFY + + V + Y
Sbjct: 1955 VKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQ 2014
Query: 239 YEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXX 298
E+LG T + V T + D C++ L QAL + G P GPAGTGKTE+ K
Sbjct: 2015 NEFLGC-TDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVV 2073
Query: 299 XFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRTPG 358
FNC + MD +GR+ GLA SG+WGCFDEFNR+ L+ Q +L+A R
Sbjct: 2074 VFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQ 2133
Query: 359 TVPTASLNGKNVSVSVWCGVAATLNPSSRGYGGXXXXXXXXXXXXXXXXXXXXXXXXXXX 418
+ + +G V ++ G+ T+NP GY G
Sbjct: 2134 FIFS---DGDCVDLNPEFGIFLTMNP---GYAGRQELPENLKIQFRTVAMMVPDRQIIMR 2187
Query: 419 XXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYDWGLRALKXXXXXXXXXXXXXXXXX 478
LA + ++ L L+ Q HYD+GLR +
Sbjct: 2188 VKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDS 2247
Query: 479 XXXXL---LAVNNVSKLTAPDARIFHKILSLVFADVKDLHATADPIVNALEGSVQ 530
+ L N+SKL D +F +++ +F ++ T + NA+ VQ
Sbjct: 2248 ELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQ 2302
>AL034345-1|CAI42433.1| 4490|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4490
Score = 165 bits (401), Expect = 4e-40
Identities = 145/535 (27%), Positives = 228/535 (42%), Gaps = 28/535 (5%)
Query: 12 RNALYFQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRLGPGGMS-VT 70
+ L F F+F+SD LLE+LGQA S+ + Q HL + I V +
Sbjct: 1575 KKRLLFPRFFFVSDPVLLEILGQA---SDSHTI--QPHLPAVSDNINEVTFHAKDYDRIM 1629
Query: 71 ALCSHFGEVFQLDHPIDIDCAVEVWLKNLENEIRSSLQNMTLKCL--VTNSLHEQDPF-- 126
A+ S GE LD+ + VE+WL +L SSL N+ +++S + PF
Sbjct: 1630 AVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLS 1689
Query: 127 SLPTQILCLAQNIRFTEQAERAI-NSKELHKFRANVEKE-----NLYYAEAETD-DENER 179
P Q+ L + +T +E A+ N+K+ K ++ N ++ D + +R
Sbjct: 1690 HFPAQVGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDR 1749
Query: 180 LKRQALILQCAYYLSVIKILIDNNVTSTSEWIWRKQFRFYLL-NTKEVVARMGLAQIPYS 238
+K + LI + + L+ ++ S +++ W KQ RFY + + V + Y
Sbjct: 1750 VKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQ 1809
Query: 239 YEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXX 298
E+LG T + V T + D C++ L QAL + G P GPAGTGKTE+ K
Sbjct: 1810 NEFLGC-TDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVV 1868
Query: 299 XFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRTPG 358
FNC + MD +GR+ GLA SG+WGCFDEFNR+ L+ Q +L+A R
Sbjct: 1869 VFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQ 1928
Query: 359 TVPTASLNGKNVSVSVWCGVAATLNPSSRGYGGXXXXXXXXXXXXXXXXXXXXXXXXXXX 418
+ + +G V ++ G+ T+NP GY G
Sbjct: 1929 FIFS---DGDCVDLNPEFGIFLTMNP---GYAGRQELPENLKIQFRTVAMMVPDRQIIMR 1982
Query: 419 XXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYDWGLRALKXXXXXXXXXXXXXXXXX 478
LA + ++ L L+ Q HYD+GLR +
Sbjct: 1983 VKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDS 2042
Query: 479 XXXXL---LAVNNVSKLTAPDARIFHKILSLVFADVKDLHATADPIVNALEGSVQ 530
+ L N+SKL D +F +++ +F ++ T + NA+ VQ
Sbjct: 2043 ELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQ 2097
>AF356519-1|AAK60620.1| 4490|Homo sapiens axonemal dynein heavy chain
8 protein.
Length = 4490
Score = 165 bits (401), Expect = 4e-40
Identities = 145/535 (27%), Positives = 228/535 (42%), Gaps = 28/535 (5%)
Query: 12 RNALYFQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRLGPGGMS-VT 70
+ L F F+F+SD LLE+LGQA S+ + Q HL + I V +
Sbjct: 1575 KKRLLFPRFFFVSDPVLLEILGQA---SDSHTI--QPHLPAVSDNINEVTFHTKDYDRIM 1629
Query: 71 ALCSHFGEVFQLDHPIDIDCAVEVWLKNLENEIRSSLQNMTLKCL--VTNSLHEQDPF-- 126
A+ S GE LD+ + VE+WL +L SSL N+ +++S + PF
Sbjct: 1630 AVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLS 1689
Query: 127 SLPTQILCLAQNIRFTEQAERAI-NSKELHKFRANVEKE-----NLYYAEAETD-DENER 179
P Q+ L + +T +E A+ N+K+ K ++ N ++ D + +R
Sbjct: 1690 HFPAQVGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDR 1749
Query: 180 LKRQALILQCAYYLSVIKILIDNNVTSTSEWIWRKQFRFYLL-NTKEVVARMGLAQIPYS 238
+K + LI + + L+ ++ S +++ W KQ RFY + + V + Y
Sbjct: 1750 VKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQ 1809
Query: 239 YEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXX 298
E+LG T + V T + D C++ L QAL + G P GPAGTGKTE+ K
Sbjct: 1810 NEFLGC-TDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVV 1868
Query: 299 XFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRTPG 358
FNC + MD +GR+ GLA SG+WGCFDEFNR+ L+ Q +L+A R
Sbjct: 1869 VFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQ 1928
Query: 359 TVPTASLNGKNVSVSVWCGVAATLNPSSRGYGGXXXXXXXXXXXXXXXXXXXXXXXXXXX 418
+ + +G V ++ G+ T+NP GY G
Sbjct: 1929 FIFS---DGDCVDLNPEFGIFLTMNP---GYAGRQELPENLKIQFRTVAMMVPDRQIIMR 1982
Query: 419 XXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYDWGLRALKXXXXXXXXXXXXXXXXX 478
LA + ++ L L+ Q HYD+GLR +
Sbjct: 1983 VKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDS 2042
Query: 479 XXXXL---LAVNNVSKLTAPDARIFHKILSLVFADVKDLHATADPIVNALEGSVQ 530
+ L N+SKL D +F +++ +F ++ T + NA+ VQ
Sbjct: 2043 ELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQ 2097
>AJ320497-1|CAC60121.1| 4523|Homo sapiens axonemal beta heavy chain
dynein type 11 protein.
Length = 4523
Score = 163 bits (395), Expect = 2e-39
Identities = 133/466 (28%), Positives = 200/466 (42%), Gaps = 38/466 (8%)
Query: 17 FQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRLGPGG--MSVTALCS 74
F FYF+S DLL++L + G++ ++V HL KLF I ++ + A+
Sbjct: 1630 FPRFYFVSSADLLDILSK---GAQPKQVTC--HLAKLFDSIADLQFEDNQDVSAHRAVGM 1684
Query: 75 HFGEVFQLDHPIDIDCA--VEVWLKNLENEIRSSLQNMTLKCLVTNSLHEQDP-----FS 127
+ E + + +C VE WL LE ++ ++++ + +V +E+ P F
Sbjct: 1685 YSKEKEYVPFQAECECVGHVETWLLQLEQTMQETVRHSITEAIVA---YEEKPRELWIFD 1741
Query: 128 LPTQILCLAQNIRFTEQAERAINS---------KELHKFRANVEKENLYYAEAETDDENE 178
P Q+ + I +T A + K+ HK + + + E +
Sbjct: 1742 FPAQVALTSSQIWWTTDVGIAFSRLEEGYETALKDFHKKQISQLNTLITLLLGELPP-GD 1800
Query: 179 RLKRQALILQCAYYLSVIKILIDNN--VTSTSEWIWRKQFRFYLLNT-KEVVARMGLAQI 235
R K + + V+ LI V S + W Q R +T K + AQ
Sbjct: 1801 RQKIMTICTIDVHARDVVAKLISQKQVVVSPQAFTWLSQLRHRWEDTQKHCFVNICDAQF 1860
Query: 236 PYSYEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXX 295
Y YEYLG + V T + D C++ LTQ+LHL G P GPAGTGKTE+ K
Sbjct: 1861 QYFYEYLGNSP-RLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGM 1919
Query: 296 XXXXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHR 355
FNC E MD + +G + GL +GAWGCFDEFNR++ + L+ V Q + A+ +R
Sbjct: 1920 MVYVFNCSEQMDYKSIGNIYKGLVQTGAWGCFDEFNRISVEVLSVVAVQVKMIHDAIRNR 1979
Query: 356 TPGTVPTASLNGKNVSVSVWCGVAATLNPSSRGYGGXXXXXXXXXXXXXXXXXXXXXXXX 415
V G+ +++ G+ T+NP GY G
Sbjct: 1980 KKRFV----FLGEAITLKPSVGIFITMNP---GYAGRTELPENLKALFRPCAMVAPDIEL 2032
Query: 416 XXXXXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYDWGLRALK 461
A LA ++TL LLS Q HYDWGLRA+K
Sbjct: 2033 ICEILLVAEGFVDARALARKFITLYTLCKELLSKQDHYDWGLRAIK 2078
>U20552-1|AAB50020.1| 161|Homo sapiens dynein heavy chain, isotype
1B protein.
Length = 161
Score = 138 bits (333), Expect = 6e-32
Identities = 67/135 (49%), Positives = 84/135 (62%), Gaps = 6/135 (4%)
Query: 258 CFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXXXFNCDEAMDAECMGRLLTG 317
C+L LTQA+ +G GNP+GPAGTGKTESVKA FNCDE +D + MGR+ G
Sbjct: 1 CYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVG 60
Query: 318 LALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAM-THRTPGTVPTASLNGKNVSVSVWC 376
L GAWGCFDEFNRL L+AV+ Q ++ A+ HRT L GK V V+
Sbjct: 61 LVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDALKNHRT-----VCELLGKEVEVNSNS 115
Query: 377 GVAATLNPSSRGYGG 391
G+ T+NP+ +GYGG
Sbjct: 116 GIFITMNPAGKGYGG 130
>Z83800-1|CAB06054.1| 179|Homo sapiens cytoplasmic dynein heavy
chain protein.
Length = 179
Score = 124 bits (298), Expect = 1e-27
Identities = 69/182 (37%), Positives = 89/182 (48%), Gaps = 6/182 (3%)
Query: 276 GPAGTGKTESVKAXXXXXXXXXXXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTS 335
GPAGTGKTESVKA FNCDE +D + MGR+ GL GAWGCFDEFNRL
Sbjct: 1 GPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEE 60
Query: 336 DTLAAVTHQFSSLLSAM-THRTPGTVPTASLNGKNVSVSVWCGVAATLNPSSRGYGGXXX 394
L+AV+ Q ++ A+ HRT L GK V V+ G+ T+NP+ +GYGG
Sbjct: 61 SVLSAVSMQIQTIQDALKNHRT-----VCELLGKEVEVNSHSGIFITMNPAGKGYGGRQK 115
Query: 395 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYD 454
A+ L+ L +F L+ LL+ Q+HYD
Sbjct: 116 LPDNLKQLFRPVAMSHPDNELIAEVILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYD 175
Query: 455 WG 456
+G
Sbjct: 176 YG 177
>AC068919-1|AAY14995.1| 2536|Homo sapiens unknown protein.
Length = 2536
Score = 122 bits (293), Expect = 4e-27
Identities = 88/316 (27%), Positives = 126/316 (39%), Gaps = 12/316 (3%)
Query: 233 AQIPYSYEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXX 292
A + Y YEYLG + V T + D C+ L ALHL G P GPAGTGKTE+ K
Sbjct: 11 AGLRYGYEYLGNSP-RLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKA 69
Query: 293 XXXXXXXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAM 352
FNC + +D +G+ GL GAW CFDEFNR+ + L+ V Q ++ +
Sbjct: 70 VAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGI 129
Query: 353 THRTPGTVPTASLNGKNVSVSVWCGVAATLNPSSRGYGGXXXXXXXXXXXXXXXXXXXXX 412
G + + C V T+NP GY G
Sbjct: 130 N----AGADILMFEGTELKLDPTCAVFITMNP---GYAGRSELPDNLKALFRTVAMMVPD 182
Query: 413 XXXXXXXXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYDWGLRALKXXXXXXXXXXX 472
A L+ + + L S LS Q HYD+G+RA+K
Sbjct: 183 YAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKL 242
Query: 473 XXXXXXXXXXLLAV---NNVSKLTAPDARIFHKILSLVFADVKDLHATADPIVNALEGSV 529
LL N+ K + D +F I S +F VK + ++ A++ +
Sbjct: 243 KYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIKDNC 302
Query: 530 QNLKLVENKAQVSEKL 545
++ L + A SEK+
Sbjct: 303 ASMNL-QMTAFFSEKI 317
>AJ132083-1|CAA10556.1| 143|Homo sapiens axonemal dynein, heavy
chain protein.
Length = 143
Score = 120 bits (290), Expect = 1e-26
Identities = 61/148 (41%), Positives = 80/148 (54%), Gaps = 5/148 (3%)
Query: 237 YSYEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXX 296
Y +EYLG +G+ V T + D C+L LT ALHL F G P GPAGTGKTE+ K
Sbjct: 1 YGFEYLGN-SGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDLGKALAIQ 59
Query: 297 XXXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRT 356
FNC + +D MG+ GLA +GAW CFDEFNR+ + L+ V Q +++ A R
Sbjct: 60 TVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQKAQQQR- 118
Query: 357 PGTVPTASLNGKNVSVSVWCGVAATLNP 384
V G + + C V T+NP
Sbjct: 119 ---VERFMFEGVEIPLVPSCAVFITMNP 143
>L23958-1|AAA16065.1| 141|Homo sapiens dynein heavy chain protein.
Length = 141
Score = 120 bits (288), Expect = 2e-26
Identities = 66/144 (45%), Positives = 79/144 (54%), Gaps = 9/144 (6%)
Query: 254 VADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXXXFNCDEAMDAECMGR 313
+ D C+L +TQAL G+PFGPAGTGKTESVKA FNCDE D + MGR
Sbjct: 1 LTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGR 60
Query: 314 LLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAM-THRTPG----TVP-TASLNG 367
+ GL GAWGCFDEFNRL L+AV+ Q + A+ H P + P T L
Sbjct: 61 IFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKTSAPITCELLN 120
Query: 368 KNVSVSVWCGVAATLNPSSRGYGG 391
K V VS + T+NP GY G
Sbjct: 121 KQVKVSPDMAIFITMNP---GYAG 141
>AY049075-1|AAL06603.1| 514|Homo sapiens dynein heavy chain
protein.
Length = 514
Score = 114 bits (274), Expect = 9e-25
Identities = 76/263 (28%), Positives = 108/263 (41%), Gaps = 9/263 (3%)
Query: 252 TEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXXXFNCDEAMDAECM 311
T + D C++ L QAL + G P GPAGTGKTE+ K FNC + MD +
Sbjct: 1 TPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGL 60
Query: 312 GRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRTPGTVPTASLNGKNVS 371
GR+ GLA SGAWGCFDEFNR+ L+ Q S +L+ + T +G NV+
Sbjct: 61 GRIFKGLAQSGAWGCFDEFNRIDLPVLSVAAQQISIILTCKKEHKKSFIFT---DGDNVT 117
Query: 372 VSVWCGVAATLNPSSRGYGGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLPHAER 431
++ G+ T+NP GY G
Sbjct: 118 MNPEFGLFLTMNP---GYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFIDNVV 174
Query: 432 LAADLHDVFTLASALLSGQRHYDWGLRALKXXXXXXXXXXXXXXXXXXXXXLLAV---NN 488
LA ++ L LS Q HYD+GLR + ++ V N
Sbjct: 175 LARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANPMDTESTIVMRVLRDMN 234
Query: 489 VSKLTAPDARIFHKILSLVFADV 511
+SKL D +F ++ +F ++
Sbjct: 235 LSKLIDEDEPLFLSLIENLFPNI 257
>U53532-1|AAB09729.1| 197|Homo sapiens cytoplasmic dynein 3 heavy
chain protein.
Length = 197
Score = 111 bits (267), Expect = 6e-24
Identities = 55/138 (39%), Positives = 74/138 (53%), Gaps = 1/138 (0%)
Query: 195 VIKILIDNNVTSTSEWIWRKQFRFYLLNTKEVVARMGLAQIPYSYEYLGTQTGQFVRTEV 254
V+ +I V+ ++++W Q R+Y N V + L + Y+YEYLG + V T +
Sbjct: 59 VVMDMIKMGVSHDTDFLWLAQLRYYWENENARVRIIQLPMLKYAYEYLGNSP-RLVITPL 117
Query: 255 ADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXXXFNCDEAMDAECMGRL 314
D C+ L A +L G P GPAGTGKTE+ K FNC + +D MG+
Sbjct: 118 TDRCYRTLIGAFYLNLGGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKF 177
Query: 315 LTGLALSGAWGCFDEFNR 332
GLA SGAW CFDEFNR
Sbjct: 178 FKGLASSGAWACFDEFNR 195
>AJ132085-1|CAA10558.1| 143|Homo sapiens axonemal dynein, heavy
chain protein.
Length = 143
Score = 111 bits (267), Expect = 6e-24
Identities = 57/148 (38%), Positives = 78/148 (52%), Gaps = 5/148 (3%)
Query: 237 YSYEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXX 296
Y +EYLG + V T + D C+ L AL L G P GPAGTGKTE+ K
Sbjct: 1 YGFEYLGNSP-RLVITPLTDRCYRTLMGALKLNLGGAPEGPAGTGKTETTKDLAKALAKQ 59
Query: 297 XXXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRT 356
FNC + +D + MG+ GLA +GAW CFDEFNR+ + L+ V Q S+ A+ +
Sbjct: 60 CVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEFNRIEVEVLSVVAQQILSIQQAIIRK- 118
Query: 357 PGTVPTASLNGKNVSVSVWCGVAATLNP 384
+ T G +S++ C V T+NP
Sbjct: 119 ---LKTFIFEGTELSLNPTCAVFITMNP 143
>Z83805-1|CAB06059.1| 177|Homo sapiens axonemal dynein heavy chain
protein.
Length = 177
Score = 101 bits (241), Expect = 9e-21
Identities = 58/184 (31%), Positives = 79/184 (42%), Gaps = 7/184 (3%)
Query: 276 GPAGTGKTESVKAXXXXXXXXXXXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTS 335
GPAGTGKTE+ K FNC + +D + MG+ GLA +GAW CFDEFNR+
Sbjct: 1 GPAGTGKTETTKVLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEFNRIEV 60
Query: 336 DTLAAVTHQFSSLLSAMTHRTPGTVPTASLNGKNVSVSVWCGVAATLNPSSRGYGGXXXX 395
+ L+ V Q S+ A+ + + T G +S++ C V T+NP GY G
Sbjct: 61 EVLSVVAQQILSIQQAIIRK----LKTFIFEGTELSLNPTCAVFITMNP---GYAGRAEL 113
Query: 396 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYDW 455
+ LA + + L S LS Q HYD+
Sbjct: 114 PDNLKALFRTVAMMVPDYALIGEISLYSMGFLDSRSLAQKIVATYRLCSEQLSSQHHYDF 173
Query: 456 GLRA 459
GL A
Sbjct: 174 GLHA 177
>AJ132084-1|CAA10557.1| 143|Homo sapiens axonemal dynein, heavy
chain protein.
Length = 143
Score = 99 bits (238), Expect = 2e-20
Identities = 52/148 (35%), Positives = 70/148 (47%), Gaps = 5/148 (3%)
Query: 237 YSYEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXX 296
Y +EYLG + V T + D C+ L ALHL G P GPAGTGKTE+ K
Sbjct: 1 YGFEYLGNSP-RLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQ 59
Query: 297 XXXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRT 356
FNC + +D +G+ GL GAW CFDEFNR+ + L+ V Q ++ +
Sbjct: 60 CVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGIN--- 116
Query: 357 PGTVPTASLNGKNVSVSVWCGVAATLNP 384
G + + C V T+NP
Sbjct: 117 -AGADILMFEGTELKLDPTCAVFITMNP 143
>U61737-1|AAC50701.1| 77|Homo sapiens dynein heavy chain protein.
Length = 77
Score = 94.7 bits (225), Expect = 8e-19
Identities = 42/77 (54%), Positives = 48/77 (62%)
Query: 252 TEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXXXFNCDEAMDAECM 311
T + D C+L +TQAL G+PFGPAGTGKTESVKA FNCDE D + M
Sbjct: 1 TPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAM 60
Query: 312 GRLLTGLALSGAWGCFD 328
GR+ GL GAWGCFD
Sbjct: 61 GRIFVGLCQVGAWGCFD 77
>AL357912-1|CAI95150.1| 234|Homo sapiens dynein, axonemal, heavy
chain 14 protein.
Length = 234
Score = 92.3 bits (219), Expect = 4e-18
Identities = 64/238 (26%), Positives = 98/238 (41%), Gaps = 8/238 (3%)
Query: 277 PAGTGKTESVKAXXXXXXXXXXXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSD 336
PAGTGKTE+VK FNC E +D + + + GL SGAW CFDEFN + +
Sbjct: 1 PAGTGKTETVKDLAKSLGKHCVVFNCFEDLDYKIVRKFFFGLVQSGAWSCFDEFNLIDLE 60
Query: 337 TLAAVTHQFSSLLSAMTHRTPGTVPTASLNGKNVSVSVWCGVAATLNPSSRGYGGXXXXX 396
L+ + Q ++ +A + + + L GK + +++ C V T+NP YGG
Sbjct: 61 VLSVIASQILTIKAAKDNYSARYL--FVLEGKEIRINMSCAVFITMNPR---YGGGVELP 115
Query: 397 XXXXXXXXXXXXXXXXXXXXXXXXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYDWG 456
A L+ L +++ LA LS Q HY++G
Sbjct: 116 DNLKSLFRPVAMMVPHYQMIAEIILFSFGFKSANSLSGKLTNLYELARKQLSQQDHYNFG 175
Query: 457 LRALKXXXXXXXXXXXXXXXXXXXXXLL-AVNNVS--KLTAPDARIFHKILSLVFADV 511
LR+LK ++ A+ S K D +F I+ +F +V
Sbjct: 176 LRSLKIVLIMAGTKKRDLSEADETLIVIEAIREASLPKCPPEDVPLFENIIGDIFPEV 233
>U61736-1|AAC50700.1| 80|Homo sapiens dynein heavy chain protein.
Length = 80
Score = 90.6 bits (215), Expect = 1e-17
Identities = 41/80 (51%), Positives = 48/80 (60%)
Query: 252 TEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXXXFNCDEAMDAECM 311
T + D C+L L AL L G P GPAGTGKTE+ K FNC + +D + M
Sbjct: 1 TPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDGLDYKMM 60
Query: 312 GRLLTGLALSGAWGCFDEFN 331
GR +GLA SGAWGCFDEFN
Sbjct: 61 GRFFSGLAQSGAWGCFDEFN 80
>Z83802-1|CAB06056.1| 179|Homo sapiens axonemal dynein heavy chain
protein.
Length = 179
Score = 89.8 bits (213), Expect = 2e-17
Identities = 59/185 (31%), Positives = 78/185 (42%), Gaps = 7/185 (3%)
Query: 276 GPAGTGKTESVKAXXXXXXXXXXXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTS 335
GPAGTGKTE+ K FNC + +D MG+ GLA SGAW CFDEFNR+
Sbjct: 1 GPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIEL 60
Query: 336 DTLAAVTHQFSSLLSAMTHRTPGTVPTASLNGKNVSVSVW-CGVAATLNPSSRGYGGXXX 394
+ L+ V Q + A+ + V L G + ++ VA T+NP GY G
Sbjct: 61 EVLSVVAQQILCIQRAIQQK---LVVFWFLEGTELKLNPGIVFVAITMNP---GYAGHSE 114
Query: 395 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYD 454
+A L+ + + L S LS Q HYD
Sbjct: 115 LPDNLKVLFRTVAMMVPNYALIAEISLYSYGFLNARPLSVKIVMTYRLCSEQLSSQFHYD 174
Query: 455 WGLRA 459
+GLRA
Sbjct: 175 YGLRA 179
>U61735-1|AAC50699.1| 79|Homo sapiens dynein heavy chain protein.
Length = 79
Score = 86.6 bits (205), Expect = 2e-16
Identities = 39/79 (49%), Positives = 47/79 (59%)
Query: 252 TEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXXXXXFNCDEAMDAECM 311
T + D C++ L QAL + G P GPAGTGKTE+ K FNC + MD +
Sbjct: 1 TPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKDVVVFNCSDQMDFRGL 60
Query: 312 GRLLTGLALSGAWGCFDEF 330
GR+ GLA SGAWGCFDEF
Sbjct: 61 GRIFKGLAQSGAWGCFDEF 79
>Z83806-1|CAB06060.1| 107|Homo sapiens axonemal dynein heavy chain
protein.
Length = 107
Score = 81.0 bits (191), Expect = 1e-14
Identities = 43/109 (39%), Positives = 58/109 (53%), Gaps = 3/109 (2%)
Query: 276 GPAGTGKTESVKAXXXXXXXXXXXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTS 335
GPAGTGKTE+ K FNC + MD +GR+ GLA SG+WGCFDEFNR+
Sbjct: 1 GPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIEL 60
Query: 336 DTLAAVTHQFSSLLSAMTHRTPGTVPTASLNGKNVSVSVWCGVAATLNP 384
L+ Q +L+A R + + +G V ++ GV T+NP
Sbjct: 61 PVLSVAAQQIYIVLTARKERKKQFIFS---DGDCVDLNPEFGVFITMNP 106
>AJ132089-1|CAA10562.1| 101|Homo sapiens axonemal dynein, heavy
chain protein.
Length = 101
Score = 81.0 bits (191), Expect = 1e-14
Identities = 37/105 (35%), Positives = 58/105 (55%), Gaps = 4/105 (3%)
Query: 280 TGKTESVKAXXXXXXXXXXXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLA 339
TGKTE+ K NC E MD +G++ +GLA GAWGCFDEFNR+ + L+
Sbjct: 1 TGKTETTKDLAKALGLLCVVTNCGEGMDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLS 60
Query: 340 AVTHQFSSLLSAMTHRTPGTVPTASLNGKNVSVSVWCGVAATLNP 384
++ Q ++ +A+ H+ + T G+ +S+ G+ T+NP
Sbjct: 61 VISSQIQTIRNALIHQ----LTTFQFEGQEISLDSRMGIFITMNP 101
>U83573-1|AAB82762.1| 102|Homo sapiens axonemal dynein heavy chain
isotype3 protein.
Length = 102
Score = 76.2 bits (179), Expect = 3e-13
Identities = 34/80 (42%), Positives = 44/80 (55%)
Query: 276 GPAGTGKTESVKAXXXXXXXXXXXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTS 335
GPAGTGKTE+ K FNC + +D MG+ GLA SGAW CFDEFNR+
Sbjct: 1 GPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIEL 60
Query: 336 DTLAAVTHQFSSLLSAMTHR 355
+ L+ V Q + A+ +
Sbjct: 61 EVLSVVAQQILCIQRAIQQK 80
>AJ132088-1|CAA10561.1| 101|Homo sapiens axonemal dynein, heavy
chain protein.
Length = 101
Score = 75.8 bits (178), Expect = 4e-13
Identities = 39/105 (37%), Positives = 56/105 (53%), Gaps = 4/105 (3%)
Query: 280 TGKTESVKAXXXXXXXXXXXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLA 339
TGKTE+ K FNC E MD + G + GLA +GAWGCFDEFNR++ + L+
Sbjct: 1 TGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLS 60
Query: 340 AVTHQFSSLLSAMTHRTPGTVPTASLNGKNVSVSVWCGVAATLNP 384
V Q S+ A+ + S G+ +S++ G+ T+NP
Sbjct: 61 VVAVQVKSIQDAIRDKK----QWFSFLGEEISLNPSVGIFITMNP 101
>AJ132086-1|CAA10559.1| 101|Homo sapiens axonemal dynein, heavy
chain protein.
Length = 101
Score = 75.4 bits (177), Expect = 5e-13
Identities = 35/105 (33%), Positives = 54/105 (51%), Gaps = 4/105 (3%)
Query: 280 TGKTESVKAXXXXXXXXXXXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLA 339
TGKTE+ K FNC + +D + MGR +GLA SGAW CFDEFNR+ + L+
Sbjct: 1 TGKTETTKDLAKALAIQCVVFNCSDGLDCKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLS 60
Query: 340 AVTHQFSSLLSAMTHRTPGTVPTASLNGKNVSVSVWCGVAATLNP 384
+ Q ++ +A + + G+ + + + C T+NP
Sbjct: 61 VIAQQLITIRNAKAAK----LSRFMFEGREIKLVMTCAAFITMNP 101
>Z83803-1|CAB06057.1| 101|Homo sapiens axonemal dynein heavy chain
protein.
Length = 101
Score = 73.3 bits (172), Expect = 2e-12
Identities = 39/104 (37%), Positives = 53/104 (50%), Gaps = 4/104 (3%)
Query: 281 GKTESVKAXXXXXXXXXXXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAA 340
GKTES K FNC E MD + G + GLA +GAW CFDEFNR+T + L+
Sbjct: 1 GKTESTKDLGRAIGIMVYVFNCSEQMDYQSCGNIYKGLAQTGAWACFDEFNRITVEVLSV 60
Query: 341 VTHQFSSLLSAMTHRTPGTVPTASLNGKNVSVSVWCGVAATLNP 384
V Q S+ A+ + T + G+ +S G+ T+NP
Sbjct: 61 VAVQVKSVQDAIRDKK----DTFNFMGEIISCVPTVGIFITMNP 100
>AJ132087-1|CAA10560.1| 101|Homo sapiens axonemal dynein, heavy
chain protein.
Length = 101
Score = 72.1 bits (169), Expect = 5e-12
Identities = 37/105 (35%), Positives = 55/105 (52%), Gaps = 4/105 (3%)
Query: 280 TGKTESVKAXXXXXXXXXXXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLA 339
TGKTE+ K FNC E MD + +G + GL +GAWGCFDEFNR++ + L+
Sbjct: 1 TGKTETTKDLGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTGAWGCFDEFNRISVEVLS 60
Query: 340 AVTHQFSSLLSAMTHRTPGTVPTASLNGKNVSVSVWCGVAATLNP 384
V Q + A+ +R V G+ +++ G+ T+NP
Sbjct: 61 VVAVQVKMIHDAIRNRKKRFV----FLGEAITLKPSVGIFITMNP 101
>U83570-1|AAB82760.1| 83|Homo sapiens axonemal dynein heavy chain
isotype2 protein.
Length = 83
Score = 70.1 bits (164), Expect = 2e-11
Identities = 28/52 (53%), Positives = 38/52 (73%)
Query: 301 NCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAM 352
NC E +D + MGR+ +GLA +GAWGCFDEFNR+ + L+ V HQ +LSA+
Sbjct: 9 NCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAHQILCILSAL 60
>Z83801-1|CAB06055.1| 169|Homo sapiens axonemal dynein heavy chain
protein.
Length = 169
Score = 69.3 bits (162), Expect = 3e-11
Identities = 44/176 (25%), Positives = 63/176 (35%), Gaps = 7/176 (3%)
Query: 281 GKTESVKAXXXXXXXXXXXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAA 340
GKTE+ K F+C + +D +G+ GL GAW CFDEFNR+ + L+
Sbjct: 1 GKTETTKDLAKAVAKQCVVFDCPDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSV 60
Query: 341 VTHQFSSLLSAMTHRTPGTVPTASLNGKNVSVSVWCGVAATLNPSSRGYGGXXXXXXXXX 400
V Q ++ + G + + C V T+NP GY G
Sbjct: 61 VAQQILTIQRGIN----AGADILMFEGTELKLDPTCAVFITMNP---GYAGRSELPDNLK 113
Query: 401 XXXXXXXXXXXXXXXXXXXXXXXXSLPHAERLAADLHDVFTLASALLSGQRHYDWG 456
A L+ + + L S LS Q HYD+G
Sbjct: 114 ALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDYG 169
>AC104600-1|AAY24051.1| 1270|Homo sapiens unknown protein.
Length = 1270
Score = 68.1 bits (159), Expect = 8e-11
Identities = 60/218 (27%), Positives = 106/218 (48%), Gaps = 17/218 (7%)
Query: 12 RNALYFQDFYFLSDDDLLELLGQARTGSEGREVVMQSHLKKLFPGITGVRLGPGGMSVTA 71
+ L+F F+FLS+D+LLE+L + + + +Q HLKK F GI V + +T
Sbjct: 1058 KKRLFFPRFFFLSNDELLEILSETKDPTR-----VQPHLKKCFEGIAKVEF-TETLDITH 1111
Query: 72 LCSHFGEVFQLDHPIDIDCA---VEVWLKNLENEIRSSLQNMTLKCLVTNSLHEQDPF-- 126
+ S GEV +L I A VE WL LE + +S+ +T + +E+ +
Sbjct: 1112 MKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHKVTGDATFAYTKYERINWVR 1171
Query: 127 SLPTQ-ILCLAQNIRFTEQAERAI--NSKELHKF--RANVEKENLYYAEAETDDENERLK 181
P Q +LC++Q I +T++ + AI K L ++ N + +++ R+
Sbjct: 1172 DWPGQTVLCVSQ-IFWTKEVQTAIPMGIKALEQYLKTCNRQIDDIVTLVRGKLSMQNRVT 1230
Query: 182 RQALILQCAYYLSVIKILIDNNVTSTSEWIWRKQFRFY 219
AL++ + V+ L+ N++ S++ W Q R+Y
Sbjct: 1231 LGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYY 1268
>U61739-1|AAC50703.1| 55|Homo sapiens dynein heavy chain protein.
Length = 55
Score = 67.3 bits (157), Expect = 1e-10
Identities = 29/55 (52%), Positives = 33/55 (60%)
Query: 277 PAGTGKTESVKAXXXXXXXXXXXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFN 331
PAGTGKTE+ K FNC + +D MG+ GLA SGAWGCFDEFN
Sbjct: 1 PAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGAWGCFDEFN 55
>U61738-1|AAC50702.1| 55|Homo sapiens dynein heavy chain protein.
Length = 55
Score = 66.5 bits (155), Expect = 2e-10
Identities = 28/55 (50%), Positives = 33/55 (60%)
Query: 277 PAGTGKTESVKAXXXXXXXXXXXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFN 331
PAGTGKTE+ K FNC + +D MG+ GLA +GAWGCFDEFN
Sbjct: 1 PAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWGCFDEFN 55
>Z83799-1|CAB06053.1| 101|Homo sapiens axonemal dynein heavy chain
protein.
Length = 101
Score = 66.1 bits (154), Expect = 3e-10
Identities = 35/104 (33%), Positives = 52/104 (50%), Gaps = 4/104 (3%)
Query: 281 GKTESVKAXXXXXXXXXXXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAA 340
GKTE+ K FNC E MD + G + GLA +GAWGCFDEFNR++ + L
Sbjct: 1 GKTETTKDLDRPLGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLYV 60
Query: 341 VTHQFSSLLSAMTHRTPGTVPTASLNGKNVSVSVWCGVAATLNP 384
+ Q + A+ + + G+ +S+ G+ T+NP
Sbjct: 61 IAVQVKCVQDAIRAKK----KKFNFLGEIISLVPTVGIFITMNP 100
>U61740-1|AAC50704.1| 54|Homo sapiens dynein heavy chain protein.
Length = 54
Score = 63.3 bits (147), Expect = 2e-09
Identities = 28/54 (51%), Positives = 32/54 (59%)
Query: 278 AGTGKTESVKAXXXXXXXXXXXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFN 331
AGTGKTE+ K FNC E MD + G + GLA +GAWGCFDEFN
Sbjct: 1 AGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFN 54
>AJ132094-1|CAB46445.1| 83|Homo sapiens axonemal dynein, heavy
chain protein.
Length = 83
Score = 63.3 bits (147), Expect = 2e-09
Identities = 27/73 (36%), Positives = 39/73 (53%)
Query: 283 TESVKAXXXXXXXXXXXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVT 342
TE+ K FNC + +D MG+ GLA +GAW CFDEFNR+ + L+ V+
Sbjct: 1 TETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVS 60
Query: 343 HQFSSLLSAMTHR 355
Q +++ A R
Sbjct: 61 QQITTIQKAQQQR 73
>Z83804-1|CAB06058.1| 101|Homo sapiens axonemal dynein heavy chain
protein.
Length = 101
Score = 60.9 bits (141), Expect = 1e-08
Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 4/85 (4%)
Query: 300 FNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHRTPGT 359
FNC + +D MG+ GLA +GAW CFDEFNR+ + L+ V Q +++ A R
Sbjct: 20 FNCSDLLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQKAQQQR---- 75
Query: 360 VPTASLNGKNVSVSVWCGVAATLNP 384
V G + + V T+NP
Sbjct: 76 VERFMFEGVEIPLVPSYAVFITMNP 100
>U83571-1|AAB82761.1| 89|Homo sapiens axonemal dynein heavy chain
isotype1 protein.
Length = 89
Score = 60.9 bits (141), Expect = 1e-08
Identities = 24/56 (42%), Positives = 35/56 (62%)
Query: 300 FNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSLLSAMTHR 355
FNC + +D MG+ GLA +GAW CFDEFNR+ + L+ V+ Q +++ A R
Sbjct: 12 FNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVSQQITTIQKAQQQR 67
>U61741-1|AAC50705.1| 55|Homo sapiens dynein heavy chain protein.
Length = 55
Score = 56.8 bits (131), Expect = 2e-07
Identities = 27/55 (49%), Positives = 32/55 (58%)
Query: 277 PAGTGKTESVKAXXXXXXXXXXXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFN 331
PAGTGKTE+VK FNC E +D + + + GL SGA GCFDEFN
Sbjct: 1 PAGTGKTETVKDLAKSLGKHCVVFNCFEDLDYKIVRKFFFGLVQSGALGCFDEFN 55
>AJ132091-1|CAA10564.1| 57|Homo sapiens axonemal dynein, heavy
chain protein.
Length = 57
Score = 55.6 bits (128), Expect = 4e-07
Identities = 22/40 (55%), Positives = 28/40 (70%)
Query: 300 FNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLA 339
FNC + MD +GR+ GLA SG+WGCFDEFNR+ L+
Sbjct: 15 FNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLS 54
>AJ132090-1|CAA10563.1| 57|Homo sapiens axonemal dynein, heavy
chain protein.
Length = 57
Score = 55.6 bits (128), Expect = 4e-07
Identities = 22/40 (55%), Positives = 28/40 (70%)
Query: 300 FNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLA 339
FNC + MD +GR+ GLA SG+WGCFDEFNR+ L+
Sbjct: 15 FNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLS 54
>U83574-1|AAB82763.1| 50|Homo sapiens axonemal dynein heavy chain
isotype3b protein.
Length = 50
Score = 52.4 bits (120), Expect = 4e-06
Identities = 22/49 (44%), Positives = 28/49 (57%)
Query: 276 GPAGTGKTESVKAXXXXXXXXXXXFNCDEAMDAECMGRLLTGLALSGAW 324
GPAGTGKTE+ K FNC + +D + MG+ GLA +GAW
Sbjct: 1 GPAGTGKTETTKDLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAW 49
>AK074178-1|BAB85004.1| 1007|Homo sapiens FLJ00251 protein protein.
Length = 1007
Score = 51.6 bits (118), Expect = 7e-06
Identities = 30/112 (26%), Positives = 49/112 (43%), Gaps = 1/112 (0%)
Query: 237 YSYEYLGTQTGQFVRTEVADECFLILTQALHLGFVGNPFGPAGTGKTESVKAXXXXXXXX 296
Y+YEYLG + G + + + + L+L AL G GP G GK V +
Sbjct: 338 YNYEYLGPRLGP-LPSLLPERPALVLLLALEEVACGTVLGPNGVGKRAIVNSLAQALGRQ 396
Query: 297 XXXFNCDEAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSL 348
C ++A+C+ L G GAW ++ ++L L+A+ + L
Sbjct: 397 LVMLPCSPQIEAQCLSNYLNGALQGGAWLLLEKVHQLPPGLLSALGQRLGEL 448
>AJ132093-1|CAB46444.1| 67|Homo sapiens axonemal dynein, heavy
chain protein.
Length = 67
Score = 44.4 bits (100), Expect = 0.001
Identities = 17/45 (37%), Positives = 26/45 (57%)
Query: 304 EAMDAECMGRLLTGLALSGAWGCFDEFNRLTSDTLAAVTHQFSSL 348
+ +D +G+ GL GAW CFDEFNR+ + L+ V Q ++
Sbjct: 1 DGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTI 45
>AC005078-1|AAC78616.2| 1020|Homo sapiens Homo sapiens dynein,
axonemal, heavy polypeptide 11 (DNAH11) protein.
Length = 1020
Score = 39.5 bits (88), Expect = 0.031
Identities = 18/33 (54%), Positives = 21/33 (63%)
Query: 429 AERLAADLHDVFTLASALLSGQRHYDWGLRALK 461
A LA ++TL LLS Q HYDWGLRA+K
Sbjct: 25 ARALARKFITLYTLCKELLSKQDHYDWGLRAIK 57
>BC019878-1|AAH19878.1| 314|Homo sapiens DNAH3 protein protein.
Length = 314
Score = 39.1 bits (87), Expect = 0.040
Identities = 28/106 (26%), Positives = 44/106 (41%), Gaps = 3/106 (2%)
Query: 432 LAADLHDVFTLASALLSGQRHYDWGLRALKXXXXXXXXXXXXXXXXXXXXXLLAV---NN 488
LA + + L S LS Q HYD+G+RA+K LL N
Sbjct: 5 LAQKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPEENESVLLLRALLDVN 64
Query: 489 VSKLTAPDARIFHKILSLVFADVKDLHATADPIVNALEGSVQNLKL 534
++K A D +F I+S +F V + + L +++ +KL
Sbjct: 65 LAKFLAQDVPLFQGIISDLFPGVVLPKPDYEVFLKVLNDNIKKMKL 110
>U83569-1|AAB82759.1| 37|Homo sapiens axonemal dynein heavy chain
isotype 11 protein.
Length = 37
Score = 35.1 bits (77), Expect = 0.66
Identities = 13/26 (50%), Positives = 17/26 (65%)
Query: 300 FNCDEAMDAECMGRLLTGLALSGAWG 325
FNC E MD + +G + GL +GAWG
Sbjct: 12 FNCSEQMDYKSIGNIYKGLVQTGAWG 37
>AY508996-1|AAS82571.1| 1606|Homo sapiens P-Rex2 protein.
Length = 1606
Score = 33.1 bits (72), Expect = 2.7
Identities = 30/112 (26%), Positives = 53/112 (47%), Gaps = 17/112 (15%)
Query: 112 LKCLVTNSLH-EQDPFSLPTQILCLAQNIRFTEQAERAINSKELHKFRANVEKENLYYAE 170
L C LH +QDP++LP+ + LAQNIR K + + + + L Y++
Sbjct: 1208 LSCPKRLRLHIKQDPWNLPSSVRTLAQNIR-----------KFVEEVKCRLLLALLEYSD 1256
Query: 171 AETDDENERLKRQALILQ-CAY---YLSVIKILIDNNVTSTSEWIWRKQFRF 218
+ET + + RQ L+ CA+ ++ + + DN+ + E W R+
Sbjct: 1257 SETQLRRDMVFRQTLVATVCAFSEQLMAALNQMFDNSKENEME-TWEASRRW 1307
>AJ437636-1|CAD26885.2| 1606|Homo sapiens P-Rex2 protein protein.
Length = 1606
Score = 31.5 bits (68), Expect = 8.1
Identities = 17/37 (45%), Positives = 24/37 (64%), Gaps = 2/37 (5%)
Query: 112 LKCLVTNSLH-EQDPFSLPTQILCLAQNIR-FTEQAE 146
L C LH +QDP++LP+ + LAQNIR F E+ +
Sbjct: 1208 LSCPKRLRLHIKQDPWNLPSSVRTLAQNIRKFVEEVK 1244
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.320 0.134 0.405
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 69,427,778
Number of Sequences: 224733
Number of extensions: 2536968
Number of successful extensions: 5098
Number of sequences better than 10.0: 73
Number of HSP's better than 10.0 without gapping: 70
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 4877
Number of HSP's gapped (non-prelim): 108
length of query: 560
length of database: 73,234,838
effective HSP length: 94
effective length of query: 466
effective length of database: 52,109,936
effective search space: 24283230176
effective search space used: 24283230176
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 68 (31.5 bits)
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