BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000897-TA|BGIBMGA000897-PA|IPR001509|NAD-dependent epimerase/dehydratase (399 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_UPI0000D55D4F Cluster: PREDICTED: similar to CG6020-PA;... 489 e-137 UniRef50_Q9VPE2 Cluster: CG6020-PA; n=7; Endopterygota|Rep: CG60... 483 e-135 UniRef50_Q5DCH0 Cluster: SJCHGC05906 protein; n=1; Schistosoma j... 302 9e-81 UniRef50_A7SNV3 Cluster: Predicted protein; n=1; Nematostella ve... 283 4e-75 UniRef50_Q9N3H3 Cluster: Putative uncharacterized protein; n=2; ... 265 2e-69 UniRef50_Q16795 Cluster: NADH dehydrogenase [ubiquinone] 1 alpha... 255 2e-66 UniRef50_UPI0000E48350 Cluster: PREDICTED: similar to MGC64316 p... 244 2e-63 UniRef50_A4S3R8 Cluster: Predicted protein; n=1; Ostreococcus lu... 213 9e-54 UniRef50_Q4PHN2 Cluster: Putative uncharacterized protein; n=1; ... 194 5e-48 UniRef50_A7Q1K0 Cluster: Chromosome chr7 scaffold_44, whole geno... 193 6e-48 UniRef50_P25284 Cluster: NADH-ubiquinone oxidoreductase 40 kDa s... 191 3e-47 UniRef50_Q6C7X4 Cluster: Similar to tr|Q86ZJ8 Podospora anserina... 190 7e-47 UniRef50_A2QSH0 Cluster: Catalytic activity: NADH + ubiquinone =... 181 3e-44 UniRef50_Q6V506 Cluster: Putative NADH:ubiquinone oxidoreductase... 174 4e-42 UniRef50_Q559Z0 Cluster: Putative uncharacterized protein; n=2; ... 165 2e-39 UniRef50_Q5KJ08 Cluster: NADH dehydrogenase (Ubiquinone), putati... 164 3e-39 UniRef50_Q5AJA9 Cluster: Potential mitochondrial Complex I, 40kd... 161 3e-38 UniRef50_UPI00006CB9E4 Cluster: hypothetical protein TTHERM_0055... 136 1e-30 UniRef50_A7HPI7 Cluster: NAD-dependent epimerase/dehydratase; n=... 115 2e-24 UniRef50_Q1GR77 Cluster: 3-beta hydroxysteroid dehydrogenase/iso... 114 4e-24 UniRef50_Q2GE21 Cluster: NADH-ubiquinone oxidoreductase family p... 113 6e-24 UniRef50_Q3YT69 Cluster: NADH-ubiquinone oxidoreductase, putativ... 112 1e-23 UniRef50_A4GHP1 Cluster: NADH-ubiquinone oxidoreductase; n=2; Ba... 112 2e-23 UniRef50_A4WW99 Cluster: NADH dehydrogenase; n=5; Rhodobacterale... 111 4e-23 UniRef50_A0BZW4 Cluster: Chromosome undetermined scaffold_14, wh... 110 5e-23 UniRef50_Q3JEV6 Cluster: NAD-dependent epimerase/dehydratase; n=... 109 1e-22 UniRef50_Q0BUA2 Cluster: NADH-ubiquinone oxidoreductase 39-40 kD... 109 2e-22 UniRef50_Q2RYH4 Cluster: 3-beta-hydroxy-delta(5)-steroid dehydro... 107 4e-22 UniRef50_Q1GCR4 Cluster: 3-beta hydroxysteroid dehydrogenase/iso... 107 5e-22 UniRef50_Q38CX2 Cluster: Putative uncharacterized protein; n=5; ... 106 1e-21 UniRef50_A7DMA8 Cluster: NAD-dependent epimerase/dehydratase; n=... 101 3e-20 UniRef50_Q98CD7 Cluster: NADH dehydrogenase (Ubiquinone) 1 alpha... 97 5e-19 UniRef50_Q4FNB8 Cluster: Probable NADH-ubiquinone oxireductase; ... 95 4e-18 UniRef50_Q2GII8 Cluster: NADH-ubiquinone oxidoreductase family p... 93 9e-18 UniRef50_Q0ACP9 Cluster: NAD-dependent epimerase/dehydratase; n=... 92 3e-17 UniRef50_Q125I6 Cluster: NAD-dependent epimerase/dehydratase; n=... 90 8e-17 UniRef50_Q1GZ10 Cluster: NAD-dependent epimerase/dehydratase; n=... 90 1e-16 UniRef50_Q6G583 Cluster: NADH-ubiquinone oxidoreductase; n=3; Ba... 89 1e-16 UniRef50_A1WZI3 Cluster: NAD-dependent epimerase/dehydratase; n=... 87 1e-15 UniRef50_A6GU58 Cluster: NAD-dependent epimerase/dehydratase; n=... 85 3e-15 UniRef50_A6FZ88 Cluster: Probable NADH-ubiquinone oxidoreductase... 85 3e-15 UniRef50_Q1PXS0 Cluster: Similar to dehydratase OleE [Streptomyc... 84 5e-15 UniRef50_Q1YEV9 Cluster: NADH-ubiquinone oxidoreductase; n=7; Al... 82 2e-14 UniRef50_A5P8M1 Cluster: NADH ubiquinone oxidoreductase, putativ... 82 2e-14 UniRef50_Q5FPV9 Cluster: Putative oxidoreductase; n=1; Gluconoba... 82 3e-14 UniRef50_A4T0E5 Cluster: NAD-dependent epimerase/dehydratase; n=... 81 7e-14 UniRef50_Q0F0X9 Cluster: NAD-dependent epimerase/dehydratase; n=... 80 9e-14 UniRef50_UPI0000E87D4F Cluster: NAD-dependent epimerase/dehydrat... 79 2e-13 UniRef50_UPI0000F21730 Cluster: PREDICTED: hypothetical protein;... 79 2e-13 UniRef50_A5FQ11 Cluster: NAD-dependent epimerase/dehydratase; n=... 77 6e-13 UniRef50_Q5P3S8 Cluster: Predicted nucleoside-diphosphate-sugar ... 77 8e-13 UniRef50_A0L6A2 Cluster: NAD-dependent epimerase/dehydratase; n=... 76 2e-12 UniRef50_A7BKW7 Cluster: NAD-dependent epimerase/dehydratase; n=... 75 3e-12 UniRef50_Q2Y682 Cluster: NAD-dependent epimerase/dehydratase; n=... 75 4e-12 UniRef50_Q1K3T7 Cluster: NAD-dependent epimerase/dehydratase; n=... 75 4e-12 UniRef50_Q1WMR0 Cluster: Putative nucleoside-diphosphate-sugar e... 74 6e-12 UniRef50_Q3JE30 Cluster: NAD-dependent epimerase/dehydratase; n=... 74 8e-12 UniRef50_Q7NWF7 Cluster: Probable NADH-ubiquinone oxidoreductase... 73 1e-11 UniRef50_Q39C42 Cluster: NAD-dependent epimerase/dehydratase; n=... 73 2e-11 UniRef50_A3ES38 Cluster: Putative nucleoside-diphosphate-sugar e... 71 4e-11 UniRef50_Q560L2 Cluster: Putative uncharacterized protein; n=2; ... 71 4e-11 UniRef50_Q67SF4 Cluster: Putative NADH-ubiquinone oxidoreductase... 70 9e-11 UniRef50_Q7NF91 Cluster: Gll3635 protein; n=1; Gloeobacter viola... 69 2e-10 UniRef50_Q476T1 Cluster: NAD-dependent epimerase/dehydratase:3-b... 67 7e-10 UniRef50_Q746J9 Cluster: NADH-ubiquinone oxidoreductase 39 kDa s... 66 1e-09 UniRef50_Q31J38 Cluster: NAD-dependent epimerase/dehydratase; n=... 66 1e-09 UniRef50_Q74G63 Cluster: NADH dehydrogenase subunit, putative; n... 64 6e-09 UniRef50_Q1IZY4 Cluster: NAD-dependent epimerase/dehydratase; n=... 62 2e-08 UniRef50_Q9HNV3 Cluster: NADH dehydrogenase/oxidoreductase-like ... 62 2e-08 UniRef50_Q3SGD6 Cluster: Nucleoside-diphosphate-sugar epimerases... 60 1e-07 UniRef50_UPI00015BC9D3 Cluster: UPI00015BC9D3 related cluster; n... 57 9e-07 UniRef50_Q4UMY6 Cluster: Putative oxidoreductase protein; n=15; ... 54 5e-06 UniRef50_Q0LC55 Cluster: NAD-dependent epimerase/dehydratase; n=... 54 5e-06 UniRef50_O54156 Cluster: Oxidoreductase; n=1; Streptomyces coeli... 54 9e-06 UniRef50_A0YYK8 Cluster: Oxidoreductase; n=1; Lyngbya sp. PCC 81... 53 1e-05 UniRef50_Q67KJ4 Cluster: Putative oxidoreductase; n=1; Symbiobac... 53 2e-05 UniRef50_Q3A8K9 Cluster: Nucleoside-diphosphate-sugar epimerases... 53 2e-05 UniRef50_O66532 Cluster: NADH dehydrogenase; n=2; Aquifex|Rep: N... 52 2e-05 UniRef50_Q2S702 Cluster: Predicted nucleoside-diphosphate-sugar ... 52 4e-05 UniRef50_A6TJS1 Cluster: 3-beta hydroxysteroid dehydrogenase/iso... 51 6e-05 UniRef50_Q6L130 Cluster: NADH-dependent oxidoreductase; n=2; The... 49 2e-04 UniRef50_Q7NW82 Cluster: Putative uncharacterized protein; n=1; ... 49 2e-04 UniRef50_Q5UYL1 Cluster: UDP-glucose 4-epimerase; n=5; Halobacte... 49 2e-04 UniRef50_A7DQP3 Cluster: 3-beta hydroxysteroid dehydrogenase/iso... 49 2e-04 UniRef50_A6DZS8 Cluster: NAD-dependent epimerase/dehydratase; n=... 48 6e-04 UniRef50_Q5NR25 Cluster: Predicted nucleoside-diphosphate-sugar ... 46 0.001 UniRef50_A2UCM7 Cluster: NAD-dependent epimerase/dehydratase; n=... 46 0.002 UniRef50_Q0LK91 Cluster: NAD-dependent epimerase/dehydratase; n=... 46 0.002 UniRef50_A1WAD5 Cluster: NAD-dependent epimerase/dehydratase; n=... 46 0.002 UniRef50_A7H7V8 Cluster: NAD-dependent epimerase/dehydratase; n=... 45 0.003 UniRef50_A7CTR2 Cluster: NAD-dependent epimerase/dehydratase; n=... 45 0.003 UniRef50_A1VGT7 Cluster: NAD-dependent epimerase/dehydratase; n=... 45 0.003 UniRef50_A0RYZ0 Cluster: Nucleoside-diphosphate-sugar epimerase;... 45 0.003 UniRef50_Q89WS9 Cluster: Bll0599 protein; n=1; Bradyrhizobium ja... 44 0.005 UniRef50_Q1YFT6 Cluster: Possible NAD-dependent epimerase/dehydr... 44 0.007 UniRef50_A3WA10 Cluster: Predicted nucleoside-diphosphate-sugar ... 44 0.007 UniRef50_A1ASP8 Cluster: NAD-dependent epimerase/dehydratase; n=... 44 0.009 UniRef50_A3YG10 Cluster: Putative uncharacterized protein; n=1; ... 43 0.012 UniRef50_Q8KDL0 Cluster: 3-beta hydroxysteroid dehydrogenase/iso... 42 0.022 UniRef50_A2C1Q9 Cluster: Putative uncharacterized protein; n=1; ... 42 0.022 UniRef50_Q2W798 Cluster: DTDP-6-deoxy-L-mannose-dehydrogenase; n... 42 0.038 UniRef50_Q2RKH0 Cluster: NAD-dependent epimerase/dehydratase; n=... 42 0.038 UniRef50_Q1LGK6 Cluster: NAD-dependent epimerase/dehydratase; n=... 42 0.038 UniRef50_A7BY73 Cluster: NAD-dependent epimerase/dehydratase; n=... 42 0.038 UniRef50_Q12VM5 Cluster: NAD-dependent epimerase/dehydratase; n=... 42 0.038 UniRef50_Q0C1U1 Cluster: Putative UDP-glucose 4-epimerase; n=1; ... 41 0.050 UniRef50_Q0ANG5 Cluster: NAD-dependent epimerase/dehydratase pre... 41 0.050 UniRef50_A3ZLP8 Cluster: NAD-dependent epimerase/dehydratase fam... 41 0.050 UniRef50_A0NYC5 Cluster: DTDP-glucose 4,6-dehydratase; n=1; Stap... 41 0.066 UniRef50_Q0S7J3 Cluster: Reductase; n=2; Nocardiaceae|Rep: Reduc... 40 0.12 UniRef50_Q0DWQ7 Cluster: Cyclin-B1-2; n=6; Oryza sativa|Rep: Cyc... 40 0.12 UniRef50_Q5ZVY7 Cluster: Oxidoreductase; n=4; Legionella pneumop... 40 0.15 UniRef50_A0A018 Cluster: MoeS5; n=4; Actinomycetales|Rep: MoeS5 ... 40 0.15 UniRef50_Q5V0D3 Cluster: DTDP-glucose-46-dehydratase; n=2; Halob... 40 0.15 UniRef50_Q2W604 Cluster: Predicted nucleoside-diphosphate-sugar ... 39 0.20 UniRef50_A1VMB7 Cluster: NAD-dependent epimerase/dehydratase; n=... 39 0.20 UniRef50_Q73MR8 Cluster: Epimerase/dehydratase, putative; n=2; B... 39 0.27 UniRef50_Q11Z70 Cluster: Nucleoside-diphosphate-sugar epimerase;... 39 0.27 UniRef50_A7FIK2 Cluster: NAD-dependent epimerase/dehydratase fam... 39 0.27 UniRef50_A4BUQ8 Cluster: DTDP-4-dehydrorhamnose reductase; n=3; ... 39 0.27 UniRef50_A3CRA1 Cluster: DTDP-4-dehydrorhamnose 3,5-epimerase, p... 38 0.35 UniRef50_Q9A4D7 Cluster: Putative uncharacterized protein; n=1; ... 38 0.46 UniRef50_Q82X00 Cluster: Putative UDP-glucose 4-epimerase; n=1; ... 38 0.46 UniRef50_Q2Y734 Cluster: NAD-dependent epimerase/dehydratase pre... 38 0.46 UniRef50_Q2S3D1 Cluster: NAD-dependent epimerase/dehydratase fam... 38 0.46 UniRef50_Q9X9X6 Cluster: Putative uncharacterized protein SCO189... 38 0.61 UniRef50_A7H9M3 Cluster: NAD-dependent epimerase/dehydratase pre... 38 0.61 UniRef50_A6G7N0 Cluster: Oxidoreductase, short chain dehydrogena... 38 0.61 UniRef50_A1ZKR0 Cluster: Putative dihydroflavonol-4-reductase; n... 38 0.61 UniRef50_Q9UXL5 Cluster: DTDP-glucose 4,6-dehydratase; n=1; Sulf... 38 0.61 UniRef50_A0B7R7 Cluster: DTDP-4-dehydrorhamnose reductase; n=1; ... 38 0.61 UniRef50_Q8KB45 Cluster: NAD-dependent epimerase/dehydratase fam... 37 0.81 UniRef50_Q11DG7 Cluster: NAD-dependent epimerase/dehydratase; n=... 37 0.81 UniRef50_A4VPL6 Cluster: DTDP-4-dehydrorhamnose reductase; n=8; ... 37 0.81 UniRef50_A1B7X9 Cluster: NAD-dependent epimerase/dehydratase; n=... 37 0.81 UniRef50_A3LUX6 Cluster: Protein FMP52-1, mitochondrial precurso... 37 0.81 UniRef50_Q1H1D1 Cluster: NAD-dependent epimerase/dehydratase; n=... 37 1.1 UniRef50_Q1ARG5 Cluster: DTDP-4-dehydrorhamnose reductase; n=1; ... 37 1.1 UniRef50_Q11CJ7 Cluster: NAD-dependent epimerase/dehydratase; n=... 37 1.1 UniRef50_Q0M547 Cluster: NAD-dependent epimerase/dehydratase:3-b... 37 1.1 UniRef50_A3ACC5 Cluster: Putative uncharacterized protein; n=2; ... 37 1.1 UniRef50_Q9HCX3 Cluster: Zinc finger protein 304; n=4; Homo sapi... 37 1.1 UniRef50_Q8KB60 Cluster: Dihydroflavonol 4-reductase family; n=8... 36 1.4 UniRef50_Q2FQM3 Cluster: Putative uncharacterized protein precur... 36 1.4 UniRef50_Q8DE28 Cluster: Nucleoside-diphosphate-sugar epimerase;... 36 1.9 UniRef50_Q3VWW5 Cluster: Dihydroflavonol 4-reductase family; n=2... 36 1.9 UniRef50_A1ULW0 Cluster: NAD-dependent epimerase/dehydratase; n=... 36 1.9 UniRef50_A0QDT4 Cluster: Putative uncharacterized protein; n=1; ... 36 1.9 UniRef50_Q0S304 Cluster: DTDP-4-dehydrorhamnose reductase; n=1; ... 36 2.5 UniRef50_Q0BVL3 Cluster: NADH-ubiquinone oxidoreductase 39-40 kD... 36 2.5 UniRef50_Q0AIT5 Cluster: NAD-dependent epimerase/dehydratase; n=... 36 2.5 UniRef50_A6LP17 Cluster: NAD-dependent epimerase/dehydratase; n=... 36 2.5 UniRef50_A5I358 Cluster: Molybdopterin biosynthesis protein; n=4... 36 2.5 UniRef50_A0Z741 Cluster: Nucleoside-diphosphate-sugar epimerase;... 36 2.5 UniRef50_A3H8S6 Cluster: NAD-dependent epimerase/dehydratase; n=... 36 2.5 UniRef50_Q2S430 Cluster: Nucleoside-diphosphate-sugar epimerase;... 35 3.3 UniRef50_A0LKC0 Cluster: NAD-dependent epimerase/dehydratase; n=... 35 3.3 UniRef50_Q8DJM2 Cluster: Nucleotide sugar epimerase; n=61; cellu... 35 4.3 UniRef50_Q6LH31 Cluster: Putative uncharacterized protein CT0995... 35 4.3 UniRef50_Q5WC54 Cluster: Putative uncharacterized protein; n=1; ... 35 4.3 UniRef50_Q5FL85 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 35 4.3 UniRef50_Q489H0 Cluster: Pseudouridine synthase; n=1; Colwellia ... 35 4.3 UniRef50_Q1ARH9 Cluster: NmrA-like protein; n=1; Rubrobacter xyl... 35 4.3 UniRef50_A5V7D1 Cluster: Short-chain dehydrogenase/reductase SDR... 35 4.3 UniRef50_Q4QE34 Cluster: Putative uncharacterized protein; n=6; ... 35 4.3 UniRef50_UPI0000D9CF92 Cluster: PREDICTED: DNA polymerase epsilo... 34 5.7 UniRef50_Q896Q0 Cluster: Transcriptional regulator, merR family;... 34 5.7 UniRef50_Q6MRE5 Cluster: Dihydroflavonol-4-reductase; n=2; Bdell... 34 5.7 UniRef50_Q2SJG1 Cluster: Nucleoside-diphosphate-sugar epimerase;... 34 5.7 UniRef50_Q8KNM3 Cluster: DTDP-6-deoxy-L-mannose-dehydrogenase; n... 34 5.7 UniRef50_Q2AZL1 Cluster: NAD-dependent epimerase/dehydratase:3-b... 34 5.7 UniRef50_Q1J1X7 Cluster: E3 binding; n=1; Deinococcus geothermal... 34 5.7 UniRef50_Q048B8 Cluster: Glycerophosphoryl diester phosphodieste... 34 5.7 UniRef50_A7FRZ5 Cluster: RNA polymerase sigma-70 factor family; ... 34 5.7 UniRef50_A4JR88 Cluster: NmrA family protein; n=2; Proteobacteri... 34 5.7 UniRef50_A3TUE1 Cluster: Putative uncharacterized protein; n=3; ... 34 5.7 UniRef50_A1K6I8 Cluster: NADH dehydrogenase; n=3; Betaproteobact... 34 5.7 UniRef50_A1BFY1 Cluster: NAD-dependent epimerase/dehydratase; n=... 34 5.7 UniRef50_A0NIS8 Cluster: NADH dehydrogenase; n=2; Oenococcus oen... 34 5.7 UniRef50_Q4XFA1 Cluster: Putative uncharacterized protein; n=1; ... 34 5.7 UniRef50_Q07864 Cluster: DNA polymerase epsilon catalytic subuni... 34 5.7 UniRef50_UPI0000E4A50F Cluster: PREDICTED: similar to Methionine... 34 7.6 UniRef50_Q7WAF7 Cluster: Putative oxidoreductase; n=3; Bordetell... 34 7.6 UniRef50_Q7UXZ2 Cluster: 3-beta-hydroxysteroid dehydrogenase; n=... 34 7.6 UniRef50_A0LUB4 Cluster: Uncharacterised conserved protein UCP03... 34 7.6 UniRef50_Q3KN81 Cluster: Leucoanthocyanidin reductase; n=3; Sper... 34 7.6 UniRef50_O22856 Cluster: Putative sterol dehydrogenase; n=1; Ara... 34 7.6 UniRef50_Q178F4 Cluster: Mpv17 protein; n=5; Endopterygota|Rep: ... 34 7.6 UniRef50_Q04304 Cluster: Uncharacterized protein YMR090W; n=5; S... 34 7.6 >UniRef50_UPI0000D55D4F Cluster: PREDICTED: similar to CG6020-PA; n=2; Endopterygota|Rep: PREDICTED: similar to CG6020-PA - Tribolium castaneum Length = 398 Score = 489 bits (1207), Expect = e-137 Identities = 231/379 (60%), Positives = 285/379 (75%), Gaps = 4/379 (1%) Query: 19 GSMSVVYIKAANYSSDRKP-NLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKI 77 G + + Y+K ANYS++ K NL+A KRGTGGRSSFNGIVATVFGC GF+GRYVCN+LGK Sbjct: 17 GFIGIAYVKTANYSTESKAYNLSALKRGTGGRSSFNGIVATVFGCGGFIGRYVCNRLGKN 76 Query: 78 GTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYET 137 G+QLILPYRGD YD RLKVCGDLGQV F P+ L DEESI K RYSNVVINL+GRD+ET Sbjct: 77 GSQLILPYRGDPYDVMRLKVCGDLGQVYFHPFDLRDEESIEKVCRYSNVVINLIGRDWET 136 Query: 138 KNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGEC 197 +NF ++DVHV G R +A++ + GVERFIHLS LNAEE P+ ++LK S + SK+ GE Sbjct: 137 RNFSFDDVHVKGARLLAKVAKRSGVERFIHLSALNAEETPEAVILKGGSKFLASKWRGEQ 196 Query: 198 AVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQ 257 AV EE+P ATI R +D+YG EDRFLR + R + +PL+K G T+KQPVFVSD+A Sbjct: 197 AVLEEFPEATIFRPADVYGQEDRFLRYYGHIWRRQATYLPLWKKGEETIKQPVFVSDLAS 256 Query: 258 GIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMRKDEKWGGYIRYDMKYDPILPLK 317 GI+ A +D DT +VYQAVGPKRY L++LVDWF+++MRKD+ W GY RYDM+YDPI ++ Sbjct: 257 GIMAALKDSDTAGKVYQAVGPKRYYLSELVDWFFRVMRKDKDW-GYWRYDMRYDPIFQIR 315 Query: 318 VALVNAISPAYPLGNLHWEGIEREATSDNVVIGVPTLEDLGVTLTHMEDQVPWELKPFR- 376 V L + +P+GNLHWE +ERE +D V VPTLEDLGV LTHMEDQVPWELKP+ Sbjct: 316 VTLTEKLRVGFPIGNLHWERVEREHVTDVVHSEVPTLEDLGVALTHMEDQVPWELKPYTY 375 Query: 377 -AHQYYMDRLGEFPKPDPP 394 +Q +D + P PP Sbjct: 376 GLYQGLVDLEEPYTPPAPP 394 >UniRef50_Q9VPE2 Cluster: CG6020-PA; n=7; Endopterygota|Rep: CG6020-PA - Drosophila melanogaster (Fruit fly) Length = 416 Score = 483 bits (1192), Expect = e-135 Identities = 238/362 (65%), Positives = 271/362 (74%) Query: 38 NLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKV 97 N AA KRGTGGRSSFNGIVATVFG TGFVGRYVCNKLGK GTQ+ILPYRGD D RLKV Sbjct: 47 NPAAMKRGTGGRSSFNGIVATVFGATGFVGRYVCNKLGKSGTQMILPYRGDDSDVIRLKV 106 Query: 98 CGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARIC 157 GDLGQVLF Y+L D SI AV++SNVVINLVGRD+ETKNFK+ DVHV+G RIARI Sbjct: 107 TGDLGQVLFHFYNLEDPASIRDAVKHSNVVINLVGRDFETKNFKFKDVHVNGAERIARIA 166 Query: 158 REEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGS 217 RE GVER IHLS LN E +PK L +K S W SKY GE VR+ +P ATIIR +DIYGS Sbjct: 167 REAGVERLIHLSSLNVEANPKDLYVKGGSEWLKSKYEGELRVRDAFPNATIIRPADIYGS 226 Query: 218 EDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVG 277 EDRFLR + R MPL+ G TVKQPV+VSDVAQ I+NAA+D D+ +YQAVG Sbjct: 227 EDRFLRYYAHIWRRQFRSMPLWHKGEKTVKQPVYVSDVAQAIINAAKDPDSAGRIYQAVG 286 Query: 278 PKRYLLADLVDWFYKLMRKDEKWGGYIRYDMKYDPILPLKVALVNAISPAYPLGNLHWEG 337 PKRY L++LVDWF++LMRKD+K GY+RYDM++DP LK L + I P P+G LH Sbjct: 287 PKRYQLSELVDWFHRLMRKDQKRWGYMRYDMRWDPTFLLKAKLNSFICPGTPIGGLHPAR 346 Query: 338 IEREATSDNVVIGVPTLEDLGVTLTHMEDQVPWELKPFRAHQYYMDRLGEFPKPDPPPVY 397 IEREA +D V+ GVPTLEDLGVTLT ME QVPWEL+P+RA YY LGEF P PP Sbjct: 347 IEREAVTDKVLTGVPTLEDLGVTLTTMEQQVPWELRPYRAALYYDAELGEFETPSPPKCI 406 Query: 398 SA 399 A Sbjct: 407 EA 408 >UniRef50_Q5DCH0 Cluster: SJCHGC05906 protein; n=1; Schistosoma japonicum|Rep: SJCHGC05906 protein - Schistosoma japonicum (Blood fluke) Length = 394 Score = 302 bits (742), Expect = 9e-81 Identities = 156/359 (43%), Positives = 232/359 (64%), Gaps = 14/359 (3%) Query: 43 KRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLG 102 KRGTGGR+SFNG+V TVFG TG++GR + L K GTQ+I+PYR D + + +KV GDLG Sbjct: 42 KRGTGGRASFNGMVVTVFGATGYLGRVLMTHLAKTGTQIIVPYRCDPHMIRGMKVVGDLG 101 Query: 103 QVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGV 162 Q+LF PY+L D+E + KA++YS+VVINL+G +++T+NF +VH+D RIA+I +E GV Sbjct: 102 QILFLPYNLKDDECLRKAMKYSDVVINLIGTEFDTRNFTIEEVHIDAACRIAKISKEIGV 161 Query: 163 ERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFL 222 E+ +H+S L ++P+ V +KPS + ISK +GE V E P ATI R ++I+G DRFL Sbjct: 162 EQLVHVSALCQNKNPQKYV-RKPSRFMISKAIGEEEVLRERPDATIFRPAEIWGPLDRFL 220 Query: 223 RSLVNKMRSHSNL----MPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGP 278 +K R H+ + +PL+ G T+KQPV+V D+A+GI+N + ++ ++Y+AVGP Sbjct: 221 CYFASKPRRHNGIQTVFVPLWSYGEHTIKQPVYVGDIARGIINCLHNPESLGQIYEAVGP 280 Query: 279 KRYLLADLVDWFYKLMRKDEKWGGYIRYDMKYDPILPLKVALVNAISPAYPLG-NLHWEG 337 RY L D+V W Y + R Y+ ++ P+ P +A + L +E Sbjct: 281 HRYRLDDIVKWIYLICR-------YLPSEIYIIPMNPWFLARTYIYENLGRINPYLTFER 333 Query: 338 IEREATSDNVVIGVPTLEDLGVTLTHMEDQVPWELKPFRAHQYYMDRLGEFPKPDPPPV 396 +ERE+ +D ++ G PTL+DL V LT +ED++ + FR Y +GEFP+P PPP+ Sbjct: 334 LERESATD-ILSGCPTLDDLNVKLTKLEDRINHIVYLFRRDYNYWHAVGEFPEPPPPPI 391 >UniRef50_A7SNV3 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 372 Score = 283 bits (695), Expect = 4e-75 Identities = 153/347 (44%), Positives = 222/347 (63%), Gaps = 21/347 (6%) Query: 43 KRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLG 102 K+GTGGRSSFNG+ ATVFG TGF+GRYV N+LG++GTQL +PYRGD +D + L++ GDLG Sbjct: 34 KKGTGGRSSFNGVSATVFGATGFLGRYVINRLGRVGTQLTVPYRGDEHDIRHLRLMGDLG 93 Query: 103 QVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGV 162 Q+ F +HL DEESIAK V++SNVV+NL+GR +ET+NF + +VHVDG R IA+ +E GV Sbjct: 94 QIDFFDFHLKDEESIAKMVKHSNVVVNLIGRGFETRNFNFEEVHVDGARTIAKAAKEAGV 153 Query: 163 ERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFL 222 ER IH+S LNA + PS + +K LGE AVREE+P ATI+R ++G ED+FL Sbjct: 154 ERLIHVSALNA-------AVDSPSKFLHTKALGEQAVREEFPNATILRPGTVFGHEDKFL 206 Query: 223 RSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYL 282 + +RS +PL + G+ T K PV+V+DVAQ I+ A +++ + + ++ VGP Y Sbjct: 207 -NYYAYLRSLPLGIPLIEGGMNTKKMPVYVADVAQSILEAIKEEASVGQTFELVGPSEYY 265 Query: 283 LADLVDWFYKLMRKDEKWGGYIRYDMKYDPILPLKVALVNAISPAYPLGN--LHWEGIER 340 L D++D+ Y++M+ + K Y +P K + A + + N L + + R Sbjct: 266 LYDIIDYIYRVMKCNFK-----HY------TVPRKAYELMAWGFEWSIFNPRLTRDMLYR 314 Query: 341 EATSDNVVIGVPTLEDLGVTLTHMEDQVPWELKPFRAHQYYMDRLGE 387 + SD + G+P LEDLG+ T + + L+ R YY + + E Sbjct: 315 QFQSDALTPGLPGLEDLGIKPTPLGAEAIAVLRRHRQSYYYEEAIDE 361 >UniRef50_Q9N3H3 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 431 Score = 265 bits (649), Expect = 2e-69 Identities = 161/391 (41%), Positives = 220/391 (56%), Gaps = 7/391 (1%) Query: 9 QATSKLLHLNGSMSVVYIKAANYSSDRKPNLAAYKRGTGGRSSFNGIVATVFGCTGFVGR 68 QA S + N S +V + A+ A +++G GGR+SF+G V TVFG +GF+G Sbjct: 14 QAVSVVGSQNFSSAVTSAENAHPEPRVSSQSAQFRKGAGGRASFSGNVVTVFGASGFLGL 73 Query: 69 YVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKAVRYSNVVI 128 V NK K G+Q+I+PYR D Y + KV G+LGQVL+ P+ L+DEESI KAV+YSNVVI Sbjct: 74 PVVNKFAKNGSQIIIPYRQDPYYMREHKVLGELGQVLYFPFELMDEESIRKAVKYSNVVI 133 Query: 129 NLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPLVLKKPSAW 188 NL+G T + Y DV+ G RR+ARIC+E GVE+F+HLS L A P+ S + Sbjct: 134 NLIGTRVPTGKYNYYDVNDTGARRLARICKEMGVEKFVHLSALGATTQPQKGHFVAKSQF 193 Query: 189 KISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMR-SHSNLMPLYKNGLATVK 247 SK LGE AVREE+P ATIIR S IYG D F++ V++ R + + + LYK G T K Sbjct: 194 LHSKGLGEVAVREEFPEATIIRPSVIYGELDGFIQYYVSRWRKTPLDYVYLYKKGEETYK 253 Query: 248 QPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMRKDEKWG-GYIRY 306 P++V DVA GI +A D K Y+ VGP Y L++L+D+ YK +G Y R+ Sbjct: 254 MPIWVGDVAAGIQSAVNDPTAKGHTYEFVGPHCYQLSELIDFMYKKAHCLSDFGFRYKRH 313 Query: 307 DM--KYDPILPLKVALVNAISPAYPLGNLHWEGIEREATSDNVVIGVPTLEDLGV-TLTH 363 M Y L + L + N W +E +++ G TL DLGV LT Sbjct: 314 GMPDPYFMALTMATELYGKVFKCKVPLNREW--MEFVEVQSDILTGERTLADLGVRRLTE 371 Query: 364 MEDQVPWELKPFRAHQYYMDRLGEFPKPDPP 394 E + ++Y+ ++ GE P P P Sbjct: 372 FELAGGQQAFYRSFNRYFEEQYGELPAPSLP 402 >UniRef50_Q16795 Cluster: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial precursor; n=38; Euteleostomi|Rep: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial precursor - Homo sapiens (Human) Length = 377 Score = 255 bits (624), Expect = 2e-66 Identities = 148/347 (42%), Positives = 215/347 (61%), Gaps = 20/347 (5%) Query: 35 RKPNLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQR 94 R+ + A G GGRSS +GIVATVFG TGF+GRYV N LG++G+Q+I+PYR D YD Sbjct: 34 RQLHHALMPHGKGGRSSVSGIVATVFGATGFLGRYVVNHLGRMGSQVIIPYRCDKYDIMH 93 Query: 95 LKVCGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIA 154 L+ GDLGQ+LF + D++SI + V++SNVVINL+GRD+ETKNF + DV V + IA Sbjct: 94 LRPMGDLGQLLFLEWDARDKDSIRRVVQHSNVVINLIGRDWETKNFDFEDVFVKIPQAIA 153 Query: 155 RICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDI 214 ++ +E GVE+FIH+S+LNA +K S + +K +GE VR+ +P A I++ SDI Sbjct: 154 QLSKEAGVEKFIHVSHLNAN-------IKSSSRYLRNKAVGEKVVRDAFPEAIIVKPSDI 206 Query: 215 YGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQ 274 +G EDRFL S + R +PL G TVKQPV+V DV++GIVNA +D D + + Sbjct: 207 FGREDRFLNSFASMHR--FGPIPLGSLGWKTVKQPVYVVDVSKGIVNAVKDPDANGKSFA 264 Query: 275 AVGPKRYLLADLVDWFYKLMRKDEKWGGYIRYDMKYDPILPLK-VALVNAISPAYPLGNL 333 VGP RYLL LV + + + + ++ + + P+ + VA V ISP P + Sbjct: 265 FVGPSRYLLFHLVKYIFAVAHR-----LFLPFPL---PLFAYRWVARVFEISPFEPW--I 314 Query: 334 HWEGIEREATSDNVVIGVPTLEDLGVTLTHMEDQVPWELKPFRAHQY 380 + +ER +D + +P LEDLG+ T +E + L+ R +++ Sbjct: 315 TRDKVERMHITDMKLPHLPGLEDLGIQATPLELKAIEVLRRHRTYRW 361 >UniRef50_UPI0000E48350 Cluster: PREDICTED: similar to MGC64316 protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to MGC64316 protein - Strongylocentrotus purpuratus Length = 378 Score = 244 bits (598), Expect = 2e-63 Identities = 135/338 (39%), Positives = 207/338 (61%), Gaps = 18/338 (5%) Query: 44 RGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQ 103 +G GGRSSF+GIVA VFG GF+G+Y+ N+LG+ G+Q+++P+R D Y Q +K+ GDLGQ Sbjct: 45 KGRGGRSSFSGIVAAVFGGNGFLGKYIVNRLGREGSQVVVPHRCDEYYVQPMKLMGDLGQ 104 Query: 104 VLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVE 163 ++F Y+L + I V VV+NL+ +DYET++F + D++++ R +A+IC+E GV Sbjct: 105 IMFRQYNLRQHDLIRDIVGNCTVVVNLLSKDYETRHFTFEDINIEAPRNLAKICKEAGVP 164 Query: 164 RFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLR 223 R IH+S L A+ + P+ + +K GE VREE+P A I+R + ++G EDRF Sbjct: 165 RLIHVSALGAD-------MASPAKFLRTKAAGERVVREEFPEAVIVRPAQMFGREDRFFN 217 Query: 224 SLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLL 283 N+ R +PL+ + VK+PV+VSDVAQ I++ + + + Y+ GP YLL Sbjct: 218 HFANQ-RFFGG-VPLFPSARRVVKRPVYVSDVAQAIMSIINEKEADGKTYELAGPNGYLL 275 Query: 284 ADLVDWFYKLMRKDEKWGGYIRYDMKYDPILPLKVALVNAISPAYPLGNLHWEGIEREAT 343 DLVD+ Y++ R+ YIRY + PIL L +A ++P P L + +E + T Sbjct: 276 TDLVDFIYRVTRRP-----YIRYPVP-RPILRL-IASGFELTPFDPF--LTRDMLELQHT 326 Query: 344 SDNVVIGVPTLEDLGVTLTHMEDQVPWELKPFRAHQYY 381 +D V G+P LEDL VT T +E L+ R+ +Y+ Sbjct: 327 TDVVQSGMPGLEDLNVTPTTVEYAAIRGLRRHRSDRYF 364 >UniRef50_A4S3R8 Cluster: Predicted protein; n=1; Ostreococcus lucimarinus CCE9901|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 366 Score = 213 bits (519), Expect = 9e-54 Identities = 118/259 (45%), Positives = 156/259 (60%), Gaps = 9/259 (3%) Query: 37 PNLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLK 96 P++ + GTGGRSSF+GI TVFG TGF+GRYV + + K G+++ILP R D Q LK Sbjct: 14 PSVTSDAVGTGGRSSFSGITCTVFGSTGFLGRYVVHHVAKSGSRMILPTRCSENDRQHLK 73 Query: 97 VCGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARI 156 V GDLGQ++ Y + DEE+I AV SNVVIN+VGR++ET+NF + DV+V +++A I Sbjct: 74 VMGDLGQIVQLDYGIRDEETIRYAVERSNVVINMVGREWETRNFSFEDVNVTFPKKLAEI 133 Query: 157 CREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYG 216 C + GV R +H+S L AEE PSA+ SK GE AVRE +P+ATI+R + I G Sbjct: 134 CADVGVRRLVHVSALGAEE-------DHPSAYYRSKAAGEAAVREAFPSATIVRPAKIVG 186 Query: 217 SEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAV 276 EDRFL R + +P+ G T QPVFV DVA I D+ T Y+ Sbjct: 187 VEDRFLNIFGEHSRKYP-AVPIIDGG-DTKHQPVFVDDVAVAIRQIVHDELTSGRTYELA 244 Query: 277 GPKRYLLADLVDWFYKLMR 295 G K Y +L K +R Sbjct: 245 GNKVYTFDELAKMVLKTIR 263 >UniRef50_Q4PHN2 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 392 Score = 194 bits (472), Expect = 5e-48 Identities = 122/289 (42%), Positives = 165/289 (57%), Gaps = 19/289 (6%) Query: 2 AAIALKTQATSKLLHLNGSMSVVYIKAANYSSDRKPNLAAYKRGT--GGRSSFNGIVATV 59 A+ AL+ +A S LL GS V + + +RK K G GGRSS +G V TV Sbjct: 13 ASSALRFEARSSLLR--GSQVVQARNVHDLTINRKTGKPIIKSGPYGGGRSSVSGHVVTV 70 Query: 60 FGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAK 119 FGCTGF+GRYV N+L + G+Q+I+PYR D + + LKV GDLGQV+ + L +E I + Sbjct: 71 FGCTGFLGRYVVNRLAQKGSQVIVPYR-DEDEKRHLKVMGDLGQVVPMEWDLRHDEQIEE 129 Query: 120 AVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKP 179 VR+S+VV NL GR YETKNF +NDVHV G +RIA+I GV RFIH+S+LNA+ + Sbjct: 130 CVRHSDVVYNLTGRHYETKNFTFNDVHVTGAQRIAQIAEASGVGRFIHVSHLNADAN--- 186 Query: 180 LVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLY 239 PSA+ SK GE V+ + ATI+R ++G EDRFL N+M + + Sbjct: 187 ----SPSAFLRSKAEGEAVVKRAFEGATIVRPGTMWGHEDRFL----NQMAVYPYAWRV- 237 Query: 240 KNGLATVKQPVFVSDVAQGIVNAARDDDTKC-EVYQAVGPKRYLLADLV 287 N T +PV DVA + D T + GPK Y + ++ Sbjct: 238 -NQGQTKMRPVHSLDVAHALEKMLEADVTSMGATFSLAGPKEYTIGQIL 285 >UniRef50_A7Q1K0 Cluster: Chromosome chr7 scaffold_44, whole genome shotgun sequence; n=6; Magnoliophyta|Rep: Chromosome chr7 scaffold_44, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 399 Score = 193 bits (471), Expect = 6e-48 Identities = 119/321 (37%), Positives = 181/321 (56%), Gaps = 16/321 (4%) Query: 43 KRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLG 102 ++GTGGRSS +GIVA VFG TGF+GRYV +L K+G+Q+++P+RG + LK+ GDLG Sbjct: 54 RKGTGGRSSVSGIVAVVFGATGFLGRYVVQQLAKMGSQVLVPFRGSEDSHRHLKLMGDLG 113 Query: 103 QVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREE-G 161 Q++ Y+ DE SI + +NVV+NL+GR+YET+N+ + +V+ ++A I +E G Sbjct: 114 QIVPMKYNPRDENSIKAVMAKANVVLNLIGREYETRNYSFEEVNHHMAEQLAMISKEHGG 173 Query: 162 VERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRF 221 + RFI +S L A PS ++K E AV E P ATI+R + + G+EDR Sbjct: 174 IMRFIQVSCLGASP-------SSPSRMLMAKAAAEEAVLRELPEATIMRPAVMIGTEDRI 226 Query: 222 LRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKC-EVYQAVGPKR 280 L + + +PLY +G +T QPV+V DVA I+ A +DD T +VY+ GP+ Sbjct: 227 LNRWAQFAKKY-GFLPLYGDG-STKFQPVYVIDVAAAIMAALKDDGTSMGKVYELGGPEI 284 Query: 281 YLLADLVDWFYKLMRKDEKWGGYIRYDMKYDPILPL-KVALVNAISPAYPLGNLHWEGIE 339 + + +L Y +R +W Y++ + L + L+N + P L + Sbjct: 285 FTMHELAAVMYDTIR---EWPRYVKVPFPIAKAMTLPREILLNKVPFPLPTPGLFNLDLI 341 Query: 340 REATSDNVVI-GVPTLEDLGV 359 TSD VV T +DLG+ Sbjct: 342 NAFTSDTVVSENALTFDDLGI 362 >UniRef50_P25284 Cluster: NADH-ubiquinone oxidoreductase 40 kDa subunit, mitochondrial precursor; n=17; Pezizomycotina|Rep: NADH-ubiquinone oxidoreductase 40 kDa subunit, mitochondrial precursor - Neurospora crassa Length = 375 Score = 191 bits (465), Expect = 3e-47 Identities = 118/338 (34%), Positives = 187/338 (55%), Gaps = 23/338 (6%) Query: 44 RGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQ 103 R GGRSS G ATVFG TG +GRY+ N+L + G +++P+R D Y+ + LKV GDLG+ Sbjct: 41 RNQGGRSSLGGHTATVFGATGQLGRYIVNRLARQGCTVVIPFR-DEYNKRHLKVTGDLGK 99 Query: 104 VLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVE 163 V+ + L + +SI ++VR+S+VV NL+GRDY TKNF + DVH++G RIA + V+ Sbjct: 100 VVMIEFDLRNTQSIEESVRHSDVVYNLIGRDYPTKNFSFEDVHIEGAERIAEAVAKYDVD 159 Query: 164 RFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLR 223 RFIH+S NA+ + + + +K GE VR +P TI+R + ++G EDR Sbjct: 160 RFIHVSSYNADPNSE-------CEFFATKARGEQVVRSIFPETTIVRPAPMFGFEDR--- 209 Query: 224 SLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLL 283 L++K+ S N+ L NG+ PV V DV Q + DD+T E ++ GPK Y Sbjct: 210 -LLHKLASVKNI--LTSNGMQEKYNPVHVIDVGQALEQMLWDDNTASETFELYGPKTYTT 266 Query: 284 ADLVDWFYKLMRKDEKWGGYIRYDMKYDPILPLKVALVNAISPAYPLGNLHWEGIEREAT 343 A++ + + + K + ++ K + P+ L A+ +P+ + + IERE Sbjct: 267 AEISEMVDREIYKRRR---HVNVPKKI--LKPIAGVLNKAL--WWPI--MSADEIEREFH 317 Query: 344 SDNVVIGVPTLEDLGVTLTHMEDQVPWELKPFRAHQYY 381 + T +DLG+ + + L+ +R++ YY Sbjct: 318 DQVIDPEAKTFKDLGIEPADIANFTYHYLQSYRSNAYY 355 >UniRef50_Q6C7X4 Cluster: Similar to tr|Q86ZJ8 Podospora anserina; n=1; Yarrowia lipolytica|Rep: Similar to tr|Q86ZJ8 Podospora anserina - Yarrowia lipolytica (Candida lipolytica) Length = 375 Score = 190 bits (462), Expect = 7e-47 Identities = 117/341 (34%), Positives = 181/341 (53%), Gaps = 25/341 (7%) Query: 44 RGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQ 103 +GTGGRSS G ATVFG GF+G Y+ KL K GT +++PYR + + LKV GDLG Sbjct: 43 KGTGGRSSRTGYTATVFGANGFLGSYLTAKLAKHGTTVVVPYREEMAK-RHLKVTGDLGV 101 Query: 104 VLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVE 163 V F L + ESI +AVR+S++V+NL+GR+YETKNF Y DVHV+G RRIA ++ + Sbjct: 102 VNFLEMDLRNLESIDEAVRHSDIVVNLIGREYETKNFNYYDVHVEGARRIAEAVKKHNIA 161 Query: 164 RFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLR 223 R+IH+S NAE + PS + +K LGE ++ P ATI+R + ++G ED++ Sbjct: 162 RYIHVSAFNAE-------IDSPSEFNHTKGLGEQVTKDIVPWATIVRPAPMFGREDKW-- 212 Query: 224 SLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLL 283 +++M L+ N PV V DVA + DD T + ++ GP+++ Sbjct: 213 -FLDRMARSPCLVS--ANKFQETSNPVHVIDVAAALERICFDDSTVAQTFELYGPQKFTQ 269 Query: 284 ADLVDWFYKLMRKDEKWGGYIRYDMKYDPILPLKVALVNAI-SPAYPLGNLHWEGIEREA 342 ++D + +RK+ +R+ + AI P Y + +ER+ Sbjct: 270 KQIIDMVSETLRKE------VRHIELPKALYQAYTKATQAIWWPTYSP-----DQVERQF 318 Query: 343 TSDNVVIGVPTLEDLGVTLTHMEDQVPWELKPFRAHQYYMD 383 S + T DL +T + D + ++P+R + + D Sbjct: 319 LSQKIDPSAKTFNDLDLTPMELPDLMFKLIRPYRVNTFQHD 359 >UniRef50_A2QSH0 Cluster: Catalytic activity: NADH + ubiquinone = NAD+ + ubiquinol; n=4; Pezizomycotina|Rep: Catalytic activity: NADH + ubiquinone = NAD+ + ubiquinol - Aspergillus niger Length = 372 Score = 181 bits (441), Expect = 3e-44 Identities = 103/242 (42%), Positives = 138/242 (57%), Gaps = 14/242 (5%) Query: 47 GGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLF 106 GGRSS G ATVFG TGF+GRY+ NKL G +++PYR + + LKV GDLG+V F Sbjct: 38 GGRSSLGGHTATVFGATGFLGRYIVNKLATQGCTVVVPYREEM-TKRHLKVTGDLGRVNF 96 Query: 107 TPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFI 166 Y L + +SI +AVR+S+VV NLVGR Y TKNF Y DVHVDG RI + V+RFI Sbjct: 97 IEYDLRNTQSIEEAVRHSDVVYNLVGRQYPTKNFSYTDVHVDGTERIVEAVAKYDVDRFI 156 Query: 167 HLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLV 226 H+S NA PS + +K GE VR YP TI+R + ++G ED +L+ Sbjct: 157 HVSSYNASR-------DSPSEYFATKAWGEEIVRNIYPETTIVRPAPMFGFED----NLL 205 Query: 227 NKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADL 286 +K+ +NL L N + PV DV + DD T + ++ GPK Y A++ Sbjct: 206 HKLARVTNL--LTSNHMQERYWPVHAIDVGTALERMLHDDSTVGQTFELYGPKNYSTAEI 263 Query: 287 VD 288 + Sbjct: 264 AE 265 >UniRef50_Q6V506 Cluster: Putative NADH:ubiquinone oxidoreductase 39 kDa subunit; n=1; Chlamydomonas reinhardtii|Rep: Putative NADH:ubiquinone oxidoreductase 39 kDa subunit - Chlamydomonas reinhardtii Length = 397 Score = 174 bits (423), Expect = 4e-42 Identities = 109/299 (36%), Positives = 167/299 (55%), Gaps = 16/299 (5%) Query: 1 MAAIALKTQATSKLLHLNGSMSVVYIKAANYSS-DRKPNL-AAYKRGTGGRSSFNGIVAT 58 M I + A S L L G + + AA+ SS D L A K G GGRSS +GI AT Sbjct: 1 MLPILGRNAAGSALARLAG---LRWAAAASQSSRDYSSTLMTADKLGPGGRSSVSGITAT 57 Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTP-YHLLDEESI 117 VFG GF+G Y+ N+L K G+Q++ P+R +A LK GDLGQ++ P + +++ I Sbjct: 58 VFGANGFLGSYIVNELAKRGSQVVCPFRSTENEAMHLKQMGDLGQIVLLPELDIRNDDDI 117 Query: 118 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEG-VERFIHLSYLNAEEH 176 +A+ SNV+IN VG +TKN+ + DVHVD +R+A++ E G V+R IH S + A+E+ Sbjct: 118 KRAISRSNVIINCVGMRLQTKNWSFEDVHVDFPKRLAKLAAETGQVQRLIHFSDMGADEN 177 Query: 177 PKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLM 236 K L ++ +K +G+ V + +P ATI+R DI G ED F L+ ++ + + Sbjct: 178 HKSLRMR-------TKAVGDKEVLDAFPDATIVRPGDIVGIEDHFYNYLIYQL-TLTVFA 229 Query: 237 PLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMR 295 P+ ++G + QP +V DVA + R DT + GP+ + ++ D K +R Sbjct: 230 PVVESGSNKI-QPTYVLDVADAVAALLRKPDTAGKTLYLGGPEVLTMREVYDLLLKTLR 287 >UniRef50_Q559Z0 Cluster: Putative uncharacterized protein; n=2; Dictyostelium discoideum|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 356 Score = 165 bits (401), Expect = 2e-39 Identities = 104/335 (31%), Positives = 172/335 (51%), Gaps = 19/335 (5%) Query: 47 GGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLF 106 G R+ G+VATVFG TGF GRY+ L + G Q+++PYR + + LKV G+LGQ++ Sbjct: 32 GSRTQTTGLVATVFGATGFTGRYLVQLLARTGIQVVVPYRCEDEGFRDLKVLGELGQIIP 91 Query: 107 TPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFI 166 + + D ESI +A+ +SN+VIN+ GRDYET+NF +D++V RIA + + VE++I Sbjct: 92 VRFDIRDSESIERAISHSNIVINMAGRDYETRNFSLDDINVHAASRIADL--SKNVEKYI 149 Query: 167 HLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLV 226 H+S L A E PS + SK +GE RE P T++R S I+G ED+F+ Sbjct: 150 HVSTLRASE-------DSPSHFSRSKAIGEKLTREIIPNCTVVRPSIIFGDEDKFINKW- 201 Query: 227 NKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADL 286 +K+ + +P Y QP+ D+A GI++ T +VY+ G + + + Sbjct: 202 SKVSQNWPFIPRYNQQHKI--QPLHCYDLASGILSILETPGTSGKVYEFAGDEVFTWDEF 259 Query: 287 VDWFYKLMRKDEKWGGYIRYDMKYDPILPLKVALVNAISPAYPLGNLHWEGIEREATSDN 346 +D + K + D +K + + N + I+ Sbjct: 260 LDMIIDGTAQYSKLNIPVSNDF-------MKFISEHLLERFARNPNFIKDQIDYHNQDMT 312 Query: 347 VVIGVPTLEDLGVTLTHMEDQVPWELKPFRAHQYY 381 +G TL+DL VT T +++++ + +R +++ Sbjct: 313 TTVGALTLKDLNVTTTPIQEKLIRLSRMYRPGKFF 347 >UniRef50_Q5KJ08 Cluster: NADH dehydrogenase (Ubiquinone), putative; n=1; Filobasidiella neoformans|Rep: NADH dehydrogenase (Ubiquinone), putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 411 Score = 164 bits (399), Expect = 3e-39 Identities = 105/259 (40%), Positives = 151/259 (58%), Gaps = 18/259 (6%) Query: 30 NYSSDRKPNLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDF 89 N S+ +P + Y TGGRSS +G TVFG TGF+ RY+ KL + GTQ+I+PYR D Sbjct: 37 NPSASVRPAIR-YGPPTGGRSSDSGRTVTVFGSTGFLARYLIQKLARQGTQVIVPYR-DE 94 Query: 90 YDAQRLKVCGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDG 149 + +RL+ CGDLGQ++ + E A+ V++++VV NLVGRDYET+N+ Y+DV+V Sbjct: 95 DEKRRLRPCGDLGQIVPLEWDARIPEQTAECVKHADVVYNLVGRDYETRNYSYDDVNVKV 154 Query: 150 VRRIARICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATII 209 + IA I + + R IH+S++NA + PS + +KY GE AVR+ +P ATI+ Sbjct: 155 AQSIAEISADMNIPRLIHVSHINANP-------ESPSEFYRTKYAGERAVRDAFPEATIV 207 Query: 210 RASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDD--D 267 R S ++G ED L+N + + L L NG T PV V DVAQ + N D Sbjct: 208 RPSQLFGHED----WLLNAIARYPILCKL-NNG-NTKLFPVHVVDVAQAL-NLMFDAPVT 260 Query: 268 TKCEVYQAVGPKRYLLADL 286 + + GP+ Y A+L Sbjct: 261 STASTFVLPGPELYNYAEL 279 >UniRef50_Q5AJA9 Cluster: Potential mitochondrial Complex I, 40kd subunit; n=5; Saccharomycetales|Rep: Potential mitochondrial Complex I, 40kd subunit - Candida albicans (Yeast) Length = 386 Score = 161 bits (391), Expect = 3e-38 Identities = 113/349 (32%), Positives = 177/349 (50%), Gaps = 21/349 (6%) Query: 30 NYSSDRKPNLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDF 89 N + + K N+A G GGRSS G ATVFG +GF+GRYV +KL + GT I+P+R D Sbjct: 31 NITKNGKVNVAV---GAGGRSSRTGYTATVFGASGFLGRYVTSKLARHGTTTIVPFRDDM 87 Query: 90 YDAQRLKVCGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDG 149 + LKV GDLG V F + +SI +V +S++VIN +G DY+TKNFK DV++ Sbjct: 88 -KKRFLKVTGDLGVVNFVEIDARNLQSIEDSVAHSDIVINCIGVDYDTKNFKMADVNIAL 146 Query: 150 VRRIARICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATII 209 RIA ++ V R+IH+S NA+ + + S + +K + E VR+ P TI+ Sbjct: 147 AERIAEATKKANVPRYIHVSSYNADPNSE-------SVFYATKGIAEQVVRDIIPDTTIV 199 Query: 210 RASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTK 269 R + +YG ED L L K++ + N A PV+V DVA+ + A DD T Sbjct: 200 RPAPMYGREDSLLNYLGPKVKMWT------PNKNAKEVWPVYVLDVARALERIAYDDSTA 253 Query: 270 CEVYQAVGPKRYLLADLVDWFYKLMRKDEKWGGYIRYDMKYDPILPLKVALVNAISPA-Y 328 + ++ GP++ ++ + + + + G + Y LPL + + Sbjct: 254 GQTFELYGPEKVTFQEIRNMIHGITENYAQVGPWSYQFADYAIPLPLAKTIAKVQQLVWW 313 Query: 329 PLGNLHWEGIEREATSDNVVIGVPTLEDLGV-TLTHMEDQVPWELKPFR 376 L N + ++R + + T DLG+ LT + D + +K +R Sbjct: 314 KLTNP--DQVQRLVINQKIDPNAKTFHDLGIDDLTRLPDVLFSYVKQWR 360 >UniRef50_UPI00006CB9E4 Cluster: hypothetical protein TTHERM_00557760; n=1; Tetrahymena thermophila SB210|Rep: hypothetical protein TTHERM_00557760 - Tetrahymena thermophila SB210 Length = 398 Score = 136 bits (329), Expect = 1e-30 Identities = 92/285 (32%), Positives = 144/285 (50%), Gaps = 20/285 (7%) Query: 23 VVYIKAANYSSDRKPNLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLI 82 ++ + +S R L Y G R S +GI AT+FG TGF+G Y+ LG IG+ +I Sbjct: 49 LIQVIQKQFSQQRSTQLKFYDGGN--RQSISGIRATIFGATGFMGPYIGAALGYIGSDVI 106 Query: 83 LPYRGDF-YD--AQRLKVCGDLGQ-VLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETK 138 P+ + YD + LK+C GQ + ++ D+ A++ SNVVINLVG + K Sbjct: 107 FPHNHVYAYDDYVKELKLCAGSGQSYIMRHFNYDDDNMYDMAIKNSNVVINLVGSRLQNK 166 Query: 139 NFK---YNDVHVDGVRRIARIC-REEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYL 194 NF+ Y ++HV ++IA C R V R IH S A+ K PS +K+ Sbjct: 167 NFQKAAYANIHV--AKKIAEACARNPNVRRLIHFSAAGAD-------TKSPSPDLHTKFH 217 Query: 195 GECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSD 254 GE AV +P ATI R +YG +D F+R + K R + + +QP+ ++D Sbjct: 218 GEEAVLNAFPNATIFRPCTVYGMQDYFIRHWI-KERDWWYHFNIVTDDCTAKRQPILIND 276 Query: 255 VAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMRKDEK 299 VAQ ++NA + ++ ++Y+ GP Y ++ + L + K Sbjct: 277 VAQCVLNALKLQESAGQIYELGGPHVYSRLEVFEMLANLSGRPPK 321 >UniRef50_A7HPI7 Cluster: NAD-dependent epimerase/dehydratase; n=1; Parvibaculum lavamentivorans DS-1|Rep: NAD-dependent epimerase/dehydratase - Parvibaculum lavamentivorans DS-1 Length = 321 Score = 115 bits (277), Expect = 2e-24 Identities = 78/231 (33%), Positives = 119/231 (51%), Gaps = 10/231 (4%) Query: 58 TVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 117 TVFG +GFVGR++ L K G ++ + R +A L+ G +GQV ++ D+ S+ Sbjct: 8 TVFGGSGFVGRHIVQTLAKRGYRIRVAVRRP-NEALFLRPMGVVGQVEPIQANIRDDASV 66 Query: 118 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 177 AV ++ V+NLVG +ET ++ V +G R+AR E G R IH+S + A+E Sbjct: 67 RAAVAGADAVVNLVGILHETGKQTFDAVQAEGAGRVARAAAEAGCGRLIHISAIGADE-- 124 Query: 178 KPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMP 237 + S + +K LGE AVR+ P A I+R S ++G D F R L P Sbjct: 125 -----ESASHYGRTKALGEKAVRDAMPDAAIVRPSIVFGPGDSFFNRFAALARLFPAL-P 178 Query: 238 LYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVD 288 L G + QPV+V DVA+G+V + VY+ GP+ +L++ Sbjct: 179 LIGGGTMRL-QPVYVKDVAEGVVQILEGEGLSGRVYEFGGPEVLTFRELME 228 >UniRef50_Q1GR77 Cluster: 3-beta hydroxysteroid dehydrogenase/isomerase; n=4; Sphingomonadaceae|Rep: 3-beta hydroxysteroid dehydrogenase/isomerase - Sphingopyxis alaskensis (Sphingomonas alaskensis) Length = 312 Score = 114 bits (274), Expect = 4e-24 Identities = 101/329 (30%), Positives = 151/329 (45%), Gaps = 29/329 (8%) Query: 51 SFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYH 110 +F+G + TV G GF+GRYV +L G ++ + R D A LK G LGQ F Sbjct: 3 TFDGQLITVLGGGGFLGRYVVQRLLARGARVRIAQR-DPRAATFLKPLGGLGQTQFVHAD 61 Query: 111 LLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSY 170 + D S+A+AV+ S+ VINLVG + + V DG +A + G +H+S Sbjct: 62 VRDAASVARAVQGSDAVINLVGAFDDMRA-----VQADGAGHVATTAKAAGARALVHVSA 116 Query: 171 LNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMR 230 + A+ PSA+ SK GE AVR + A I+R S I+G EDRF+ MR Sbjct: 117 IGADRD-------SPSAYGRSKGDGEAAVRAAFTGAAILRPSIIFGREDRFINRFAGMMR 169 Query: 231 SHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWF 290 + +MP+ QPV+V DVA +V A D T +++ GP+ + +L+ W Sbjct: 170 L-APVMPVI--APQAKFQPVYVGDVADAVVAALADTATG-RLFELGGPQVLTMRELLRWI 225 Query: 291 YKLMRKDEKWGGYIRYDMKYDPILPLKVALVNAISPAYPLGNLHWEGIEREATSDNVVI- 349 + + + L +A +P P+ W ++ SDNVV Sbjct: 226 ADATGRSPLF-------IDVPDFLASALATGFGWAPGAPITRDQWLMLQ----SDNVVAS 274 Query: 350 GVPTLEDLGVTLTHMEDQVPWELKPFRAH 378 G L +LG+T T + L +R H Sbjct: 275 GAAGLAELGITPTPLAAVADGWLVQYRRH 303 >UniRef50_Q2GE21 Cluster: NADH-ubiquinone oxidoreductase family protein; n=1; Neorickettsia sennetsu str. Miyayama|Rep: NADH-ubiquinone oxidoreductase family protein - Neorickettsia sennetsu (strain Miyayama) Length = 340 Score = 113 bits (273), Expect = 6e-24 Identities = 78/238 (32%), Positives = 122/238 (51%), Gaps = 13/238 (5%) Query: 58 TVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 117 TVFG +GF+G YV +L K G ++ + A++LK+ G+LGQ+ + + I Sbjct: 34 TVFGGSGFIGSYVVRELVKSGYRVTV-VANSLSCAKKLKLSGNLGQISVVHGDIRYPDDI 92 Query: 118 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 177 K + S +VIN+VG ET + + ++ ++A+I E GV RFIH S L Sbjct: 93 VKGIGNSEIVINMVGVLRETSSASFGAINHLACAQVAQIAAENGVRRFIHFSAL------ 146 Query: 178 KPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRS-HSNLM 236 L + + SK GE AVR +P + IIR ++G ED F+ V R L+ Sbjct: 147 --LGCNGATKYGKSKLNGEEAVRSAFPESIIIRPGVVFGEEDNFINLFVKLGRKLRILLL 204 Query: 237 PLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLM 294 P K A++ QPV+V D+A + +++ K E+Y VG KRY L ++ +L+ Sbjct: 205 PACKT--ASI-QPVYVGDLALLVAKILQNETLKGEIYPVVGSKRYTLNEICSLISRLL 259 >UniRef50_Q3YT69 Cluster: NADH-ubiquinone oxidoreductase, putativ; n=8; Rickettsiales|Rep: NADH-ubiquinone oxidoreductase, putativ - Ehrlichia canis (strain Jake) Length = 320 Score = 112 bits (270), Expect = 1e-23 Identities = 69/238 (28%), Positives = 124/238 (52%), Gaps = 11/238 (4%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 +FG +GF+GRY+ + G +I + A++LK+CG+LGQ+ + + + I Sbjct: 8 IFGGSGFIGRYLVKYFAENG-YIIKIFTRYPEKAKQLKLCGNLGQIEVISGDVTNVQEIE 66 Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 178 + +VV+NL+G Y TKN + D+H IA+ + VE +H S + +E Sbjct: 67 NNIFGCHVVVNLLGTLYSTKNSTFYDIHAKAAENIAKAAKSCDVELMVHFSAMGIDE--- 123 Query: 179 PLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPL 238 + S + SK +GE V+ +P A IIR + ++G+EDRF K+ S +P+ Sbjct: 124 ----VQQSHYARSKLIGENLVKLAFPNAVIIRPNLVFGAEDRFFNKFA-KLTMISPFLPV 178 Query: 239 YKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMRK 296 G A V QP++V D+A+ + + T ++Y GP+ Y +L+++ ++++ Sbjct: 179 IGGGRA-VFQPIYVDDLAKFVFYIVNNAVTD-KLYNVCGPRTYSFKELLNFILSIIKR 234 >UniRef50_A4GHP1 Cluster: NADH-ubiquinone oxidoreductase; n=2; Bacteria|Rep: NADH-ubiquinone oxidoreductase - uncultured marine bacterium EB0_39F01 Length = 330 Score = 112 bits (269), Expect = 2e-23 Identities = 77/241 (31%), Positives = 125/241 (51%), Gaps = 12/241 (4%) Query: 56 VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 115 + T+FG +GFVGRYV ++ K G ++ + R +A +K GD+GQV ++ DE+ Sbjct: 7 LVTIFGGSGFVGRYVAQRMAKEGWRVRVAVRRP-NEALFVKTYGDVGQVEPILANIRDEK 65 Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 175 S A+ ++ V+N VG ET K+ D+ G +IA++ E GV+ F+H S + A+ Sbjct: 66 STRAAIIGADAVVNCVGILNETSKQKFTDLQSKGASQIAKLATECGVKTFVHFSAIGADI 125 Query: 176 HPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNL 235 + LK SK GE V+ + A I+R S ++G+ED+F M S L Sbjct: 126 NSHSKYLK-------SKAEGEEMVKASFKNAVILRPSIVFGAEDQFFNRFAT-MAKLSPL 177 Query: 236 MPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMR 295 +PL G T QPV+V D+A+ V + K +Y+ GP+ +L+ ++R Sbjct: 178 IPLV--GGETKFQPVYVDDIAKAAVKGVL-GEAKRGIYELGGPQAASFKELIIMLMGIIR 234 Query: 296 K 296 + Sbjct: 235 R 235 >UniRef50_A4WW99 Cluster: NADH dehydrogenase; n=5; Rhodobacterales|Rep: NADH dehydrogenase - Rhodobacter sphaeroides ATCC 17025 Length = 328 Score = 111 bits (266), Expect = 4e-23 Identities = 93/327 (28%), Positives = 150/327 (45%), Gaps = 16/327 (4%) Query: 56 VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 115 + T++G +GFVGRY+ ++ + G ++ + R +A +K G +GQV ++ D+ Sbjct: 4 LVTIYGGSGFVGRYIARRMAQQGWRVRVAVRRP-NEALFVKPYGVVGQVEPVFCNIRDDA 62 Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 175 S+ + ++ V+N VG E ++ V +G R+AR+ EGV+ + +S + A+ Sbjct: 63 SVRAVMHGADAVVNCVGILAEAGKNRFQSVQAEGAARVARLAAAEGVQALVQISAIGAD- 121 Query: 176 HPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNL 235 PSA+ SK GE AV + +P A I+R S I+G ED F +M S + Sbjct: 122 ------ADSPSAYARSKAAGEAAVLQAFPRAVILRPSVIFGPEDDFFNRFA-RMARFSPV 174 Query: 236 MPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMR 295 +P+ G T QPVFV DVAQ V A +Y+ GP L+ L+R Sbjct: 175 LPVV--GGETRFQPVFVDDVAQAAV-AGVLGRAAPGIYELGGPDAESFRALMQ---MLLR 228 Query: 296 KDEKWGGYIRYDMKYDPILPLKVALVNAISPAYPLGNLHWEGIEREATSDNVVI-GVPTL 354 E+ + ++ + L+ ++ R DNVV G L Sbjct: 229 VIERRKMIVNVPFGVARLMAATLDLLQTVTLGLLANKTLTRDQVRNLARDNVVSPGARGL 288 Query: 355 EDLGVTLTHMEDQVPWELKPFRAHQYY 381 DLG++ T ME +P L +R Y Sbjct: 289 ADLGISPTAMEAVLPEYLWSYRPSGQY 315 >UniRef50_A0BZW4 Cluster: Chromosome undetermined scaffold_14, whole genome shotgun sequence; n=4; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_14, whole genome shotgun sequence - Paramecium tetraurelia Length = 351 Score = 110 bits (265), Expect = 5e-23 Identities = 83/273 (30%), Positives = 136/273 (49%), Gaps = 21/273 (7%) Query: 36 KPNLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDF-YD--A 92 +P L + +G + + +GI AT+ G T F G Y+ LG IG++LI P+ + Y+ Sbjct: 14 RPKLHIFDKGA--KHTPSGIRATIHGGTSFSGIYMGGMLGNIGSELIFPHNHQYNYEDHV 71 Query: 93 QRLKVCGDLGQV-LFTPYHLLDEESIAKAVRYSNVVINLVG---RDYETKNFKYNDVHVD 148 + LK GQ L + ++E I ++ SNVV+NL+G + K F+ + + Sbjct: 72 RELKTTSGPGQNWLLHDMNYDNKEMIEWTMKNSNVVVNLLGPQKTSEKQKGFRVDQLSQC 131 Query: 149 GVRRIARICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATI 208 ++ + GV R IH S A H + L L+ +KY+GE V +P ATI Sbjct: 132 QKEQLKHALKTPGVIRLIHFSACGANPHAESLDLQ-------TKYIGEQEVLNAFPNATI 184 Query: 209 IRASDIYGSEDRFLRSL-VNKMRSHS-NLMPLYKNGLATVKQPVFVSDVAQGIVNAARDD 266 R S + G D F V K H+ N++P + +QP+FV DVAQ ++NA + Sbjct: 185 FRPSVMVGDNDDFAYHWQVQKRYFHNFNIVP---DNCQAKRQPIFVQDVAQAMLNALKMP 241 Query: 267 DTKCEVYQAVGPKRYLLADLVDWFYKLMRKDEK 299 +T + Y+ GP Y L + + F+ ++++ K Sbjct: 242 ETIGQTYELGGPHVYTLLECYEMFHNIVQRPPK 274 >UniRef50_Q3JEV6 Cluster: NAD-dependent epimerase/dehydratase; n=1; Nitrosococcus oceani ATCC 19707|Rep: NAD-dependent epimerase/dehydratase - Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) Length = 308 Score = 109 bits (263), Expect = 1e-22 Identities = 69/231 (29%), Positives = 120/231 (51%), Gaps = 14/231 (6%) Query: 58 TVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 117 TVFG TGF+GR + ++L + G ++ + R + + G GQ+ + DE+S+ Sbjct: 13 TVFGGTGFLGRAIVHRLVESGMRVRIVAR----HPRAPNLAGARGQIALQRADVRDEDSV 68 Query: 118 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 177 A+A++ + V+N VG E + +H +G R+AR E G+ R IH+S + + Sbjct: 69 AEALKGATGVVNAVGLYVEQGQATFRAIHEEGAERVARRAGEAGIRRLIHISGIGVDP-- 126 Query: 178 KPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMP 237 S + ++ GE VRE +P ATI+R S ++G D FL SL K + ++P Sbjct: 127 -----ASASKYARARAYGEQRVREIFPNATILRPSVMFGPNDAFLNSL--KTVTRLPVVP 179 Query: 238 LYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVD 288 L+ G +T QPV+V DVA+ ++ + + ++ G + Y D+++ Sbjct: 180 LFGQG-STRLQPVYVEDVARAVLQVLEMPEASGKTFELGGARAYRYRDIIE 229 >UniRef50_Q0BUA2 Cluster: NADH-ubiquinone oxidoreductase 39-40 kDa subunit-like protein; n=2; Acetobacteraceae|Rep: NADH-ubiquinone oxidoreductase 39-40 kDa subunit-like protein - Granulobacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1) Length = 333 Score = 109 bits (261), Expect = 2e-22 Identities = 103/333 (30%), Positives = 158/333 (47%), Gaps = 28/333 (8%) Query: 49 RSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTP 108 +S+ G +ATVFG +GF+G+ + L + G Q+ +P R D +LK G +GQ++ Sbjct: 11 QSTMAGRIATVFGGSGFLGQSLIRLLAREGYQVRVPVR-DPEQVLKLKSAGSVGQIVPLG 69 Query: 109 YHLLD---EESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERF 165 L E IA+AV+ +++V+NLVG E + + VHV IA + + GV F Sbjct: 70 VSLGSRDAEAGIARAVQGASLVVNLVGLLAEARKGDFQRVHVQAAGLIASLSAQAGVLSF 129 Query: 166 IHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSL 225 +H+S L A+ PSA+ SK GE AVR P A I+R S ++G+ED F Sbjct: 130 MHISALGADP-------ASPSAYGRSKAEGEEAVRSAVPQAAILRPSVVFGAEDHFFNRF 182 Query: 226 VNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLAD 285 S + +Y N + QPV+V DVA+ I+ AA V + GP+ + D Sbjct: 183 AAMAVSLPVVPVIYGN---SRMQPVYVEDVARAILAAA--TQAAGNVIELGGPEVLTMRD 237 Query: 286 LVDWFYKLMRKDEKWGGYIRYDMKYDPILPLKVALVNA-ISPAYPLGNLHWEGIEREATS 344 + ++ + + D +P KVA+ A I+ P L + + + Sbjct: 238 IQHRILTMIGRKKP-----LID------IPDKVAMALAMIAEKMPGRPLTTDQLAMLGSG 286 Query: 345 DNVVIGVPTLEDLGVTLTHMEDQVPWELKPFRA 377 V TLE LG+ T ++ VP L FRA Sbjct: 287 SVVSPQALTLETLGIVPTPIDLVVPHYLSRFRA 319 >UniRef50_Q2RYH4 Cluster: 3-beta-hydroxy-delta(5)-steroid dehydrogenase; n=3; Rhodospirillaceae|Rep: 3-beta-hydroxy-delta(5)-steroid dehydrogenase - Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255) Length = 340 Score = 107 bits (258), Expect = 4e-22 Identities = 80/260 (30%), Positives = 130/260 (50%), Gaps = 26/260 (10%) Query: 54 GIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLD 113 G V TVFG +G +GR + L G ++ + R D A LK G LGQ+ + D Sbjct: 3 GRVVTVFGGSGSIGRQLVALLADQGARVRVAVR-DTEKAHFLKPLGQLGQIAPISASVSD 61 Query: 114 EESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA 173 S+ +AV ++ V+NLVG E+ + VHVDG +AR E GV+ IH+S L A Sbjct: 62 AASVKRAVEGADQVVNLVGILAESGRRTFQAVHVDGAATVARASAEAGVDALIHMSALGA 121 Query: 174 EEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHS 233 +E + + +K LGE AVRE +P ATI+R S ++G +D F +L ++ S Sbjct: 122 DE-------ASDANYSKTKALGEKAVREAFPAATILRPSVVFGPDDGFF-NLFAGLQRLS 173 Query: 234 NLMPLYK--------NGLATVK---------QPVFVSDVAQGIVNAARDDDTKCEVYQAV 276 ++P + +G+ + QPV+V DVA+ ++ + + Y+ Sbjct: 174 PVLPYFTRDGFRRGGSGVCGIDLAGSGGPKFQPVYVGDVARAMIAILDTPALRGKTYELG 233 Query: 277 GPKRYLLADLVDWFYKLMRK 296 GP+ Y + +++D + R+ Sbjct: 234 GPRVYSMKEIMDLVVAVTRR 253 >UniRef50_Q1GCR4 Cluster: 3-beta hydroxysteroid dehydrogenase/isomerase; n=17; Rhodobacterales|Rep: 3-beta hydroxysteroid dehydrogenase/isomerase - Silicibacter sp. (strain TM1040) Length = 329 Score = 107 bits (257), Expect = 5e-22 Identities = 91/335 (27%), Positives = 153/335 (45%), Gaps = 19/335 (5%) Query: 56 VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 115 + T++G +GFVGRY+ ++ K G ++ + R +A +K G GQV ++ D+ Sbjct: 4 LVTIYGGSGFVGRYIARRMAKEGWRVRVAVRRP-NEAMHVKPYGVPGQVEPVFCNIRDDA 62 Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 175 S+A + ++ V+N VG E ++ V +G RIARI + GVER +H+S + A+ Sbjct: 63 SVAAVMAGADAVVNCVGVLNEVGKNTFSAVQSEGAGRIARIAADTGVERLVHVSAIGAD- 121 Query: 176 HPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNL 235 SA+ +K GE AV E +P+A I+R S I+G ED+F + M + Sbjct: 122 ------ADGDSAYARTKAEGEAAVLEAFPSAMILRPSIIFGPEDQFFNRFAS-MTRFGPV 174 Query: 236 MPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMR 295 +P+ G T QPV+V DVA+ V A Y+ GP+ +L+ ++ Sbjct: 175 LPI--AGGTTRFQPVYVDDVAKAAV-AGLTGQAAAGTYELGGPEVKSFTELMSQMLDVIH 231 Query: 296 KDEKWGGYIRYDMKYDPILPLKVALVNAISPAYPLGNLHWEGIEREATSDNVVI-GVPTL 354 + + + ++ + A++ L + +DNVV G L Sbjct: 232 RRRLVVSLPNFVAR---LMAFGFDMAQAVTFGLFTNGLLTRDQLKNLQNDNVVSEGAKGL 288 Query: 355 EDLGVTLTHMEDQVP---WELKPFRAHQYYMDRLG 386 DLG+ M +P W+ +P + M G Sbjct: 289 ADLGIEPVTMGSVLPDYLWKFRPSGQYDELMKSAG 323 >UniRef50_Q38CX2 Cluster: Putative uncharacterized protein; n=5; Trypanosomatidae|Rep: Putative uncharacterized protein - Trypanosoma brucei Length = 373 Score = 106 bits (254), Expect = 1e-21 Identities = 79/259 (30%), Positives = 126/259 (48%), Gaps = 23/259 (8%) Query: 44 RGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYR---GDFYDAQRLKVCGD 100 RG G ++ G+ FG TG +G ++ + G I+P+R G + L++ GD Sbjct: 19 RGGGSEANAMGVNVATFGATGVLGTHIHHLCCYHGFTSIVPFRFRAGMASGVRHLRMAGD 78 Query: 101 --LGQVLFTPYHLLDEESIAKAVRYS-NVVINLVGR-----DYETKN--FKYNDVHVDGV 150 +GQ T Y + D+E + K++ + VIN VG YE F ++V+ Sbjct: 79 GTVGQNFDTDYEI-DKEFVVKSILEKVDNVINAVGAWQEPAVYENSQSWFSMEAINVEWP 137 Query: 151 RRIARICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIR 210 R +AR CRE G+ R H+S + A+ H +L++ A E AV EE+PTATIIR Sbjct: 138 RMLARWCREMGILRLTHMSMVGADLHSPSKLLRQKRA-------AEIAVLEEFPTATIIR 190 Query: 211 ASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKC 270 +DI+ D + R + ++P+ G + QPVF D+A+ + D T+ Sbjct: 191 GTDIFAENDYSYSRYLMAQRKY-KIVPMPNRG-QRIHQPVFAGDLAEATCRSILLDHTEG 248 Query: 271 EVYQAVGPKRYLLADLVDW 289 + + GP R+ AD + W Sbjct: 249 RIAELGGPVRFTTADYLRW 267 >UniRef50_A7DMA8 Cluster: NAD-dependent epimerase/dehydratase; n=3; Alphaproteobacteria|Rep: NAD-dependent epimerase/dehydratase - Methylobacterium extorquens PA1 Length = 389 Score = 101 bits (243), Expect = 3e-20 Identities = 104/341 (30%), Positives = 162/341 (47%), Gaps = 32/341 (9%) Query: 56 VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 115 + TVFG +GF+GR+V L K G ++ + R A L+ G +GQ++ +L + Sbjct: 18 LVTVFGGSGFLGRHVVRALAKRGYRIRVAVRRPDL-ALFLQPLGKVGQIVGVQANLRYPD 76 Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 175 SI +AV +S++VINLVG E+ + +++ + +G IAR G + +H+S L A+ Sbjct: 77 SIRRAVEHSDIVINLVGILQESGSQRFSKLQTEGAGEIARAAAAVGA-KLVHVSALGADP 135 Query: 176 HPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNL 235 PS + SK LGE V P A I R S ++G D F N+ S + Sbjct: 136 -------DSPSLYARSKALGEAEVLRASPDAVIFRPSLVFGPGDGFF----NRFASLATF 184 Query: 236 MP-LYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLM 294 +P L G T QPVFV DVA+ I A VY+ GP+ + +++F + M Sbjct: 185 LPALPLAGAQTRFQPVFVGDVAEAIARAVDGLAAGGRVYELGGPE----VNTLEYFVRYM 240 Query: 295 RKDEKWGGYIRYDMKYDPILPLKVALVNAISPAYPLGNLHWE-GIEREATS----DNVVI 349 + + D+ +P+ L+ ++ I+ LG L + R+ + DNVV Sbjct: 241 LEVTMRRRAV-LDLP-EPVARLQARVIE-IADTLTLGLLPANLKLTRDQVALLQFDNVVS 297 Query: 350 GVP-----TLEDLGVTLTHMEDQVPWELKPFR-AHQYYMDR 384 T+E LG+ T +E VP L FR A Q+ R Sbjct: 298 DAAKAEGRTIEALGIVPTAVEAVVPGYLWRFRKAGQFAQGR 338 >UniRef50_Q98CD7 Cluster: NADH dehydrogenase (Ubiquinone) 1 alpha subcomplex; n=31; Alphaproteobacteria|Rep: NADH dehydrogenase (Ubiquinone) 1 alpha subcomplex - Rhizobium loti (Mesorhizobium loti) Length = 341 Score = 97.5 bits (232), Expect = 5e-19 Identities = 73/223 (32%), Positives = 112/223 (50%), Gaps = 11/223 (4%) Query: 56 VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 115 + VFG +GFVGR+V L K G ++ + R A L+ G++GQ+ ++ Sbjct: 26 LVVVFGGSGFVGRHVVRALAKRGYRIRVACRRPDL-AGHLQPLGNVGQIQPVQANVRVRW 84 Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 175 S+ +AV+ ++ V+NLV +ET K++ VH G R +A R G H+S L A+ Sbjct: 85 SVDRAVQGADHVVNLVAILHETGRQKFSAVHEFGSRAVAEAARSVGA-GLTHISALGAD- 142 Query: 176 HPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNL 235 L S + +K LGE AV E P A I R S +G ED F + M +S + Sbjct: 143 ------LDSESDYARTKALGEKAVLETIPDAVIFRPSINFGPEDSFFNRFAS-MARYSPV 195 Query: 236 MPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGP 278 +PL G T QPV+V DVA+ + + + ++Y+ GP Sbjct: 196 LPLIGGG-QTKFQPVYVGDVAEAVARSVDGKIDRGQIYELGGP 237 >UniRef50_Q4FNB8 Cluster: Probable NADH-ubiquinone oxireductase; n=2; Candidatus Pelagibacter ubique|Rep: Probable NADH-ubiquinone oxireductase - Pelagibacter ubique Length = 322 Score = 94.7 bits (225), Expect = 4e-18 Identities = 65/239 (27%), Positives = 116/239 (48%), Gaps = 11/239 (4%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 +FG +G +GR++ KL K ++ + R +K + G + ++ DE+ I Sbjct: 8 IFGGSGQIGRHLIRKLTKNNYKVTVVTRNLHQKGYAIKTQANAGYIDIVEANIFDEKKIR 67 Query: 119 KAVRYSNVVINLVGRDYET-KNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 177 K +++ INL+G YE+ K + ++H ++++C+E V++FIHLS L + P Sbjct: 68 KLFSQTDICINLIGILYESGKGNTFKNIHSIFPSILSKLCKEYKVQQFIHLSALGINDAP 127 Query: 178 KPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMP 237 S + SK GE +++ +P ATI+R S +Y +D F S + + S P Sbjct: 128 -------DSEYAKSKLDGELNIQKNFPLATILRPSVVYSVDDNFTTSFMT-LLSRLPFFP 179 Query: 238 LYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMRK 296 LY NG +T P+ SD+ I + ++ + VGP L +++ L+ K Sbjct: 180 LYYNG-STKFAPIHCSDLTDTIYHVV-SKSIYSKIIECVGPDILSLKEILKKLLHLIDK 236 >UniRef50_Q2GII8 Cluster: NADH-ubiquinone oxidoreductase family protein; n=2; Anaplasma|Rep: NADH-ubiquinone oxidoreductase family protein - Anaplasma phagocytophilum (strain HZ) Length = 313 Score = 93.5 bits (222), Expect = 9e-18 Identities = 74/233 (31%), Positives = 110/233 (47%), Gaps = 20/233 (8%) Query: 59 VFGCTGFVGRY-VCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 117 VFG +GF+GRY VC + + + Y + A RLK+ G LGQV L D I Sbjct: 6 VFGGSGFIGRYLVCELVAR--KYSVTVYTRNHEKAARLKLFGRLGQVDIVCGKLSDAALI 63 Query: 118 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 177 K + +V++NLVG + + +HV IA++ + G + F+H S + A+ Sbjct: 64 QKLIADCDVIVNLVGTISDPRGAVLQYLHVTFPSNIAKLATKHG-KMFVHFSAMGAD--- 119 Query: 178 KPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMP 237 + K S++ SK GE +R+ A I+R + ++G D F N R + MP Sbjct: 120 ----IAKTSSYAQSKLEGEKRIRDVCEDAVILRPNLVFGDGDNFFNKFANLARV-APFMP 174 Query: 238 LYKNGLATVKQPVFVSDVAQGIVNAARD---DDTKCEVYQAVGPKRYLLADLV 287 L+ G + QPV V DV VN A D + Y+ GP Y L DL+ Sbjct: 175 LFGGG-KNLLQPVHVDDV----VNVAMDLIVNQASSGTYEVAGPTVYSLKDLI 222 >UniRef50_Q0ACP9 Cluster: NAD-dependent epimerase/dehydratase; n=1; Alkalilimnicola ehrlichei MLHE-1|Rep: NAD-dependent epimerase/dehydratase - Alkalilimnicola ehrlichei (strain MLHE-1) Length = 320 Score = 91.9 bits (218), Expect = 3e-17 Identities = 71/235 (30%), Positives = 111/235 (47%), Gaps = 19/235 (8%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 + G +GF+G + +LG+ G ++I+P R +R + + V ++ DE+++ Sbjct: 8 ILGGSGFIGTTIAGRLGRDGHRVIVPTR----HRERSRHLLPVPNVEVVELNVNDEDALV 63 Query: 119 KAVRYSNVVINLVGRDYETKNFK---YNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 175 +A + VINLVG E K + HV+ RR+ C+ GV R++H+S L A+ Sbjct: 64 EAFQDCTAVINLVGILNELSGPKGEGFRRAHVELPRRVISACQRAGVGRYLHMSALGADP 123 Query: 176 HPKPLVLKKPSAWKISKYLGE---CAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSH 232 + PS ++ +K GE A + + T R S ++GS D F +R Sbjct: 124 -------EGPSLYQQTKGEGERLAIAAHGDGLSVTAFRPSVVFGSGDSFFNRFAGLLRLS 176 Query: 233 SNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287 M L QPV+V+DVA + D T +VY VGPKRY L LV Sbjct: 177 PGFMFLPTPHAEF--QPVWVNDVASAFIRCLEDQATGGQVYDLVGPKRYTLEALV 229 >UniRef50_Q125I6 Cluster: NAD-dependent epimerase/dehydratase; n=3; Comamonadaceae|Rep: NAD-dependent epimerase/dehydratase - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 318 Score = 90.2 bits (214), Expect = 8e-17 Identities = 84/304 (27%), Positives = 142/304 (46%), Gaps = 24/304 (7%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 + G TGFVGR+VC KL ++ ++ + R +A+ L+ L V+ H D ++ Sbjct: 6 ILGGTGFVGRHVCEKLAQLQCRVTVATRR-LDNARHLQTLPML-DVIEIDVH--DSAALT 61 Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 178 + + V+NL+ + T+ + HV + R C G+ R +H+S L A Sbjct: 62 SLLAGHDAVVNLIAILHGTEA-AFEKAHVQLPLALVRACEAAGLRRIVHISALGAS---- 116 Query: 179 PLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPL 238 + S ++ SK GE + T++R S I+G+ED+FL + + L P+ Sbjct: 117 ---VSSASMYQRSKARGEAVLLSAGLDVTLLRPSVIFGAEDKFLNTFARLQQ----LFPV 169 Query: 239 YKNGLATVK-QPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMRKD 297 + + QPV+V DVA +V+ +D + +VY+A GP + L LV+ + + Sbjct: 170 VPLAASQARFQPVWVEDVASAVVHCLQDSSSIGQVYEACGPDVFTLRQLVELAGRYAGVN 229 Query: 298 EKWGGYIRYDMKYDPILPLKVALVNAISPAYPLGNLHWEGIEREATSDNVVIG-VPTLED 356 GG R + L A + + P PL L + ++ T DNV G +P L+ Sbjct: 230 ---GGKGRPVIALPAPLGRLQARLMELLPGEPL--LSRDNLDAMQT-DNVASGKLPGLKA 283 Query: 357 LGVT 360 LG+T Sbjct: 284 LGIT 287 >UniRef50_Q1GZ10 Cluster: NAD-dependent epimerase/dehydratase; n=1; Methylobacillus flagellatus KT|Rep: NAD-dependent epimerase/dehydratase - Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875) Length = 321 Score = 89.8 bits (213), Expect = 1e-16 Identities = 77/245 (31%), Positives = 117/245 (47%), Gaps = 20/245 (8%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQL-ILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 117 V G +GFVG + ++L G + +L R + ++ L + L V T + +E S+ Sbjct: 9 VVGGSGFVGSALVHRLSTAGYDVKVLTRRRE--SSKHLIL---LPNVQVTECDVFNEASL 63 Query: 118 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 177 + + + VINL G +E+ N + +HVD RIA IC ++GV R +H+S L A Sbjct: 64 SGQLHGQDAVINLAGILHESGNATFESIHVDLATRIADICCKQGVPRLLHMSALKASADA 123 Query: 178 KPLVLKKPSAWKISKYLGECAV--REEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNL 235 K SA+ SK GE AV R + T+ R S I+G D FL L N + N+ Sbjct: 124 K-------SAYLRSKAAGEQAVLRRADELQVTVFRPSVIFGRGDHFLSMLANVV----NM 172 Query: 236 MPLYKNGLATVK-QPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLM 294 MP+ K QP++V DVA + A + T GP+ Y L L++ L+ Sbjct: 173 MPVVAVAKPNAKFQPIWVEDVAYVFLTALENVSTYGRSIDLGGPQVYTLKQLIELTALLL 232 Query: 295 RKDEK 299 K + Sbjct: 233 GKKRR 237 >UniRef50_Q6G583 Cluster: NADH-ubiquinone oxidoreductase; n=3; Bartonella|Rep: NADH-ubiquinone oxidoreductase - Bartonella henselae (Rochalimaea henselae) Length = 334 Score = 89.4 bits (212), Expect = 1e-16 Identities = 85/331 (25%), Positives = 150/331 (45%), Gaps = 18/331 (5%) Query: 58 TVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 117 TVFG +GFVGR+V L K G ++ + R L++ G++GQ + S+ Sbjct: 17 TVFGGSGFVGRHVVEALTKRGYRVRIAVRSPQKAYYMLQI-GEVGQTQMLRTDIKCRASV 75 Query: 118 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 177 A+A+ S+ + L G + + ++G + ++ + E G+ I++S L A ++ Sbjct: 76 ARALLGSDGAVFLPGSLAQANQPNFQKTQIEGAQNVSELTAEAGIP-LIYMSALVANKNA 134 Query: 178 KPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMP 237 L + S + E + E+P A I+R S I+G ED F +L N + ++P Sbjct: 135 SFLYARVKS-------MSEEIIHNEHPQAIIMRPSIIFGPEDCFFNNLAN-LSCFLPIIP 186 Query: 238 LYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLM-RK 296 L+ G + + QPV+V DVA+ IV A + Y GP+ +++++ K++ RK Sbjct: 187 LFGGGQSKL-QPVYVGDVAEFIVRALEGQVISGKSYDLGGPQIITFQNVLEYILKIIHRK 245 Query: 297 DEKWGGYIRYDMKYDPILPL--KVALVNAISPAYPLGNLHWEGIEREATSDNVVIGVPTL 354 + + +L K+ L + A + L + I + +N TL Sbjct: 246 KTILSMPLSAGLFIGGLLGTIGKLPLAPTLVTASQIRFLQIDNIVSQEAIENGY----TL 301 Query: 355 EDLGVTLTHMEDQVPWELKPFRAHQYYMDRL 385 E +G+T M +P L FR H + L Sbjct: 302 EGVGITPKAMAALLPSYLWRFRPHGQFSRNL 332 >UniRef50_A1WZI3 Cluster: NAD-dependent epimerase/dehydratase; n=1; Halorhodospira halophila SL1|Rep: NAD-dependent epimerase/dehydratase - Halorhodospira halophila (strain DSM 244 / SL1) (Ectothiorhodospirahalophila (strain DSM 244 / SL1)) Length = 320 Score = 86.6 bits (205), Expect = 1e-15 Identities = 76/241 (31%), Positives = 109/241 (45%), Gaps = 19/241 (7%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 V G TGFVG +V N+L G ++ R L G ++ H DE + Sbjct: 8 VVGGTGFVGMHVANRLADRGYRIRALTRRSHRGRDLLLFPGL--RLFEADVH--DERELV 63 Query: 119 KAVRYSNVVINLVGRDYET---KNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 175 + + VINL G + Y++VHVD RR+ R V R +H+S L A Sbjct: 64 RHFSGCHAVINLAGAHTGRGGPREDAYHEVHVDLPRRVLAAARRASVPRLVHMSALGA-- 121 Query: 176 HPKPLVLKKPSAWKISKYLGECAVREEYPT---ATIIRASDIYGSEDRFLRSLVNKMRSH 232 HP + S + +K GE V P AT+++ S I+G+ DRFL +R Sbjct: 122 HPDAV-----SRFLRTKGEGEQLVLAADPDEIGATVLQPSVIFGAGDRFLNRFAGLLRFA 176 Query: 233 SNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYK 292 + L QPVF DVAQ ++NA D T + YQ GP+ Y L +LV++ + Sbjct: 177 PGVFFLPTPDARL--QPVFGGDVAQAVINATEDPRTAGQTYQLCGPQIYTLRELVEYVAE 234 Query: 293 L 293 L Sbjct: 235 L 235 >UniRef50_A6GU58 Cluster: NAD-dependent epimerase/dehydratase; n=1; Limnobacter sp. MED105|Rep: NAD-dependent epimerase/dehydratase - Limnobacter sp. MED105 Length = 317 Score = 85.0 bits (201), Expect = 3e-15 Identities = 70/238 (29%), Positives = 117/238 (49%), Gaps = 24/238 (10%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 V G +GF+G+ VCN+L K G ++ +P R YD + + Q++ H D ++ Sbjct: 2 VIGGSGFLGQAVCNQLAKAGYRITVPTRR--YDKAKHLLTLPTCQIIEANIH--DRATLG 57 Query: 119 KAVRYSNVVINLVGRDYET------KNFKYNDVHVDGVRRIARICREEGVERFIHLSYLN 172 + V ++V+NL+G + +NF+ N HV+ + + + G +R +H+S L Sbjct: 58 RLVSGQDIVVNLLGVLHSKPGKPYGQNFRVN--HVEFPKALCTAMSKHGAKRIVHVSALG 115 Query: 173 AE-EHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRS 231 ++P P S + SK GE V++ TI+R S ++G ED+FL + + + Sbjct: 116 VGVQNPAP------SMYLRSKTDGEAVVKDSGLAWTILRPSVVFGREDKFLNTFAS-LAK 168 Query: 232 HSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDD--DTKCEVYQAVGPKRYLLADLV 287 + +PL G QPV VSDVA+ + D DT Y VG + + L +LV Sbjct: 169 IAPFIPL--AGADARFQPVSVSDVAKAVFACVEDQGKDTLHNTYDLVGTEIFTLKELV 224 >UniRef50_A6FZ88 Cluster: Probable NADH-ubiquinone oxidoreductase; n=1; Plesiocystis pacifica SIR-1|Rep: Probable NADH-ubiquinone oxidoreductase - Plesiocystis pacifica SIR-1 Length = 554 Score = 85.0 bits (201), Expect = 3e-15 Identities = 78/246 (31%), Positives = 118/246 (47%), Gaps = 29/246 (11%) Query: 55 IVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCG-DLGQVLFT-PYHLL 112 + V G +GF+GR+V + L G ++++ RG + L+ G +L +V F P+ Sbjct: 2 LTVAVAGGSGFIGRHVVDHLRAQGCRVVVLARG----LRGLEGEGVELRRVDFAGPW--- 54 Query: 113 DEESIAKAVRYSNVVINLVG--RDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSY 170 E A + + V+NLVG R + HV+ + +A R EG+ERF+H+S Sbjct: 55 -SEQGASLLAGCDAVVNLVGIKRAGRGSGLSFEAAHVELPKALAEAARREGIERFVHVSV 113 Query: 171 LNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMR 230 A HP+ S + +K GE AVRE +P ATI+R +YG D LR+L + +R Sbjct: 114 AGARRHPR-------STYLDTKARGEAAVREGFPAATILRPGVVYGRGDDMLRNLADSVR 166 Query: 231 S----HSNLMPLYKNGLATVKQ----PVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYL 282 + + P G T PV V DVA+ + A + + +V VGP R Sbjct: 167 AAPVFPAPRRPRSATGTGTGTWAELCPVAVEDVAEAVWRAV-EGRGQGQVLDVVGP-RTT 224 Query: 283 LADLVD 288 L LVD Sbjct: 225 LPRLVD 230 >UniRef50_Q1PXS0 Cluster: Similar to dehydratase OleE [Streptomyces antibioticus]; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Similar to dehydratase OleE [Streptomyces antibioticus] - Candidatus Kuenenia stuttgartiensis Length = 297 Score = 84.2 bits (199), Expect = 5e-15 Identities = 62/236 (26%), Positives = 114/236 (48%), Gaps = 15/236 (6%) Query: 61 GCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKA 120 G TGFVG+ + NKL + ++ R K+ + Q+ + D + A Sbjct: 7 GSTGFVGKQLLNKLIENKYKVKCLVR----KGSEHKLGQYINQIEVVNGDITDPPCLKNA 62 Query: 121 VRYSNVVINLVG--RDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 178 + VIN+VG R+ K + +H +G + R +++GV+RFI +S L A++ K Sbjct: 63 IADCEAVINIVGIIREIPGKGVTFEKLHYEGTHNLIREAKKQGVDRFIQMSALGAKQEGK 122 Query: 179 PLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPL 238 L ++ +K+L E +R+ TI R S I+G ED+F+ + ++ +P+ Sbjct: 123 TL-------YQQTKFLAEECIRKSGLNYTIFRPSIIFGKEDKFVNTFAGMLKI-QQFIPV 174 Query: 239 YKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLM 294 +G + QPV V +V V++ DT + Y+ GP++ D+++ K++ Sbjct: 175 IGDGKYKL-QPVAVENVVAAFVDSIERRDTFGKSYEVGGPEKIEFNDIINIIGKVL 229 >UniRef50_Q1YEV9 Cluster: NADH-ubiquinone oxidoreductase; n=7; Alphaproteobacteria|Rep: NADH-ubiquinone oxidoreductase - Aurantimonas sp. SI85-9A1 Length = 369 Score = 82.2 bits (194), Expect = 2e-14 Identities = 66/238 (27%), Positives = 116/238 (48%), Gaps = 11/238 (4%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 VFG +GFVGRY+ L + G ++ + R A L+ G++GQ++ +L S+ Sbjct: 46 VFGGSGFVGRYLVQALARRGHRIRVACRRPDL-AYHLQPNGNMGQIMPIQANLRYPWSVE 104 Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 178 +AV ++ V+NLVG ++ ++ + G R +A + G +S + A+E+ Sbjct: 105 RAVEGADHVVNLVGILAQSGQQSFDALQSFGARTVAEATAKIGAG-MTQISAIGADEN-- 161 Query: 179 PLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPL 238 S + +K GE AV + P A I+R S ++G+ED+F + M S +PL Sbjct: 162 -----SGSEYARTKAEGEKAVLDAIPGAYIMRPSIVFGAEDQFFNRFAD-MARFSPFLPL 215 Query: 239 YKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMRK 296 G T QPV+V DVA+ I + VY+ GP+ +++ +++ + Sbjct: 216 IGGG-KTRFQPVYVGDVAEAIADTVDGKVPGGRVYELGGPEVLTFRQMMEEMLRIIER 272 >UniRef50_A5P8M1 Cluster: NADH ubiquinone oxidoreductase, putative; n=3; Erythrobacter|Rep: NADH ubiquinone oxidoreductase, putative - Erythrobacter sp. SD-21 Length = 344 Score = 82.2 bits (194), Expect = 2e-14 Identities = 84/339 (24%), Positives = 153/339 (45%), Gaps = 34/339 (10%) Query: 51 SFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYH 110 + NG + G TGF+G YV L G +L + R A +LK +LGQ+ F Sbjct: 34 ALNGKTVALMGGTGFLGNYVAQALLSRGARLRICGRNP-QAAFKLKPLANLGQLQFARMD 92 Query: 111 LLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRR--IARICREEGVERFIHL 168 D S+ + ++ ++ V+NLVG +F + + G +A ++ G F+H+ Sbjct: 93 ATDRRSVEQCIKGADAVVNLVG------SFDGDLARLMGEAPGWMAEAAKKTGAMSFVHV 146 Query: 169 SYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNK 228 S + AE + + +K++GE V E + ATI+R S I+G +D FL ++ + Sbjct: 147 SAIAAEPEED-----WSNEYASAKHMGERRVTEAFKNATIVRPSIIFGKDDNFL-NMFGE 200 Query: 229 MRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTK-CEVYQAVGPKRYLLADLV 287 + S ++P++ G Q V+V DVA+ I + + + Y+ GP++ + ++ Sbjct: 201 LISKLPVLPVF--GPEAELQLVYVDDVAEAIAQSVENPGKHGGKTYELGGPEKLSMIEI- 257 Query: 288 DWFYKLMRKDEKWGGYIRYDMKYDPILPLKVALVNAISPAYPLGNLHWEGIEREATSDNV 347 + + R + P +P V+ A P P+G+ W+ +++ NV Sbjct: 258 ---------NRRIADAQRRKRTFLP-MPDGVSATFAALPGTPMGSDQWDLLKQ----GNV 303 Query: 348 VIG-VPTLEDLGVTLTHMEDQVPWELKPFRAHQYYMDRL 385 G P E G+ + + + FR H + +RL Sbjct: 304 ASGDYPGFEKFGIEPKPLGLFLDKWMTRFRKHGRFAERL 342 >UniRef50_Q5FPV9 Cluster: Putative oxidoreductase; n=1; Gluconobacter oxydans|Rep: Putative oxidoreductase - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 340 Score = 81.8 bits (193), Expect = 3e-14 Identities = 93/323 (28%), Positives = 144/323 (44%), Gaps = 29/323 (8%) Query: 54 GIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLD 113 G V V G GFVGR + +L G + + D + GD G+V F + D Sbjct: 32 GRVVAVLGGGGFVGRELVGRLVASGHVVRVGSGNPEADQALARFPGD-GRVEFIKASVND 90 Query: 114 EESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA 173 +S+ ++ INLV + V+V+G R A + R EGVE+++H+S + A Sbjct: 91 ADSLEHLFSGADAGINLVSIMSPDVKAMHR-VNVEGARLAALVARREGVEQYLHMSAIGA 149 Query: 174 EEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLR--SLVNKMRS 231 ++ P + SK L E VRE +P A ++R S I+G ED F +L+ K+ Sbjct: 150 S-------IQSPGNYGRSKGLAERVVREVFPEAALLRPSVIFGPEDSFFNMFALIAKL-- 200 Query: 232 HSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFY 291 S ++P++ G+ QPV+V DVA+ + + V +A GP + +L+ + Sbjct: 201 -SPVLPVFAAGMRF--QPVYVGDVARAAMALVTPERAGMTV-EAGGPDVLTMKELMAFVL 256 Query: 292 KLMRKDEKWGGYIRYDMKYDPILPLKVALVNAISPAYPLGNLHWEGIEREATSDNVV-IG 350 + G R+ + P+ L I P G+L DNVV G Sbjct: 257 EA-------SGRRRFLL---PVPDCVAKLEAEILEPLP-GHLLTRDQVVMMGLDNVVQPG 305 Query: 351 VPTLEDLGVTLTHMEDQVPWELK 373 L+ LG+T T M VP LK Sbjct: 306 ADDLQSLGITPTAMRSVVPDYLK 328 >UniRef50_A4T0E5 Cluster: NAD-dependent epimerase/dehydratase; n=1; Polynucleobacter sp. QLW-P1DMWA-1|Rep: NAD-dependent epimerase/dehydratase - Polynucleobacter sp. QLW-P1DMWA-1 Length = 302 Score = 80.6 bits (190), Expect = 7e-14 Identities = 70/235 (29%), Positives = 114/235 (48%), Gaps = 17/235 (7%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDE-ESI 117 + G GFVGR + +L G +++P + L++ + + H DE +++ Sbjct: 7 LIGGNGFVGRVIAAQLQAAGYSVLIP-TSHVVAGRELRLLPKV-HLEDADVHDFDELQNL 64 Query: 118 AKAVRYSNVVINLVGRDYETKNFKYNDV----HVDGVRRIARICREEGVERFIHLSYLNA 173 ++ VINLVG ++ + Y V HVD + I + G++R++H+S L A Sbjct: 65 CGRIQLRGAVINLVGVLHDKEAQPYGKVFKAAHVDLPKNIITAMQLHGLKRYLHMSALGA 124 Query: 174 EEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHS 233 + PS ++ SK GE AV+ TI R S I+G++D+F+ +L +K+ Sbjct: 125 NS-------QGPSMYQRSKGDGELAVKASSLDWTIFRPSVIFGAQDQFI-NLFSKLTKLF 176 Query: 234 NLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVD 288 +PL N A QPV V DVA V A T +VY VGP Y + ++V+ Sbjct: 177 PALPL-ANYQAQF-QPVSVDDVASAFVGALTMPQTIHQVYDLVGPTVYSMKEIVE 229 >UniRef50_Q0F0X9 Cluster: NAD-dependent epimerase/dehydratase; n=1; Mariprofundus ferrooxydans PV-1|Rep: NAD-dependent epimerase/dehydratase - Mariprofundus ferrooxydans PV-1 Length = 317 Score = 80.2 bits (189), Expect = 9e-14 Identities = 67/231 (29%), Positives = 106/231 (45%), Gaps = 17/231 (7%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 V G +GFVGR + + G + + R A+ + V G V ++D I Sbjct: 7 VIGGSGFVGRAIAKQAVTAGHTVTVGCRHP-ERARAMLVDG----VRLKRVDVVDGRGID 61 Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 178 +A++ + VI LVG +E + + HVDGV + C+ GV +++H+S L A P Sbjct: 62 EAIKGCDTVIYLVGLLFERGRYNFQAAHVDGVEHVLAACQRAGVGQYLHMSALGAGAVP- 120 Query: 179 PLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPL 238 S++ SK E VR TI R S IYG+ D F +K ++ S+ +P+ Sbjct: 121 ------GSSYATSKGEAEKHVRASGLNWTIFRPSIIYGAGDSFF----SKFKTISSALPV 170 Query: 239 YKNGLATVK-QPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVD 288 + QPV+V DVA+ V + T + Y+ GP Y L++ Sbjct: 171 MPVICGETRFQPVWVEDVARAFVGTIGNRHTANQCYELGGPATYSFKQLLE 221 >UniRef50_UPI0000E87D4F Cluster: NAD-dependent epimerase/dehydratase; n=1; Methylophilales bacterium HTCC2181|Rep: NAD-dependent epimerase/dehydratase - Methylophilales bacterium HTCC2181 Length = 293 Score = 79.4 bits (187), Expect = 2e-13 Identities = 60/235 (25%), Positives = 120/235 (51%), Gaps = 21/235 (8%) Query: 56 VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPY-HLLDE 114 V ++FG TGF+G + ++L K ++ L R K+ L + T + L D+ Sbjct: 3 VVSIFGGTGFIGTELIHELEKKNYEIRL--------FTRRKIPHTLNTLSKTRFIQLRDD 54 Query: 115 ESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 174 ++ + S+++I+LVG +E K ++DVH ++++++I ++ ++RFIH+ L A Sbjct: 55 TKLSNELIGSDIIIDLVGILHEQKGITFDDVHSGRLKKLSKIAQKLNIKRFIHIGALGAS 114 Query: 175 EHPKPLVLKKPSAWKISKYLGECAVREEYPTA--TIIRASDIYGSEDRFLRSLVNKMRSH 232 + PS + SK GE ++++ TI + S ++G +D+F+ +L + + S Sbjct: 115 -------VNAPSKYLQSKGKGEKHIKKQCSNLAWTIYKPSIVFGIDDKFV-NLFHNIISF 166 Query: 233 SNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287 + ++ L ++ QP++V D+ I+N D T + + GP Y L+ Sbjct: 167 TPIIGLISP--HSMFQPIWVKDLVDIIINGIDDKKTFQKTFNVAGPTSYSFMGLI 219 >UniRef50_UPI0000F21730 Cluster: PREDICTED: hypothetical protein; n=1; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 392 Score = 79.0 bits (186), Expect = 2e-13 Identities = 40/95 (42%), Positives = 61/95 (64%), Gaps = 7/95 (7%) Query: 139 NFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECA 198 N+KY DV V +IAR RE G+++FIH+S+LNA+ ++ PS + +K +GE A Sbjct: 302 NYKYEDVFVSIPLQIARATREAGIKKFIHMSHLNAD-------IRSPSKYLRNKAVGEEA 354 Query: 199 VREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHS 233 VR E+P A I++ S+++G EDRFL +K +S Sbjct: 355 VRNEFPDAIIMKPSELFGREDRFLNHFASKCLENS 389 >UniRef50_A5FQ11 Cluster: NAD-dependent epimerase/dehydratase; n=3; Dehalococcoides|Rep: NAD-dependent epimerase/dehydratase - Dehalococcoides sp. BAV1 Length = 302 Score = 77.4 bits (182), Expect = 6e-13 Identities = 64/237 (27%), Positives = 113/237 (47%), Gaps = 14/237 (5%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 V G +GFVGR++ +L + G ++ L + +A R+K G V F + D + Sbjct: 7 VTGGSGFVGRHLLPRLAENGFKIRLLVMNET-EANRVKTPG----VEFVYGTVNDLPVLM 61 Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 178 +++ +I+LV E KN + +V+++G + + E GV+RFIH+ L A P+ Sbjct: 62 DSLKDVFAIIHLVAILRENKNATFAEVNIEGTKNMLAAATENGVKRFIHMGILGASADPR 121 Query: 179 PLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPL 238 L SKYL E AVR +I++ S ++G F+ +L+ + + + P+ Sbjct: 122 FTYLH-------SKYLAEEAVRHSGLGYSILKPSVMFGPGAGFINALIRSFKPYPCIAPV 174 Query: 239 YKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMR 295 NG T QP++V DV ++ + V Q GP+ + ++ + MR Sbjct: 175 AGNG-KTRLQPIWVEDVVSCLLKMLEGEKIHQSV-QIGGPQIFTYDQVLSAVMQAMR 229 >UniRef50_Q5P3S8 Cluster: Predicted nucleoside-diphosphate-sugar epimerases; n=4; Betaproteobacteria|Rep: Predicted nucleoside-diphosphate-sugar epimerases - Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) Length = 321 Score = 77.0 bits (181), Expect = 8e-13 Identities = 69/241 (28%), Positives = 108/241 (44%), Gaps = 20/241 (8%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 + G +GF+G V N+L ++++P R A R + L V + D ++A Sbjct: 8 LIGGSGFLGSAVANQLAGAAVEVVVPTRR----ASRARHLLLLPTVDVVEADVHDPATLA 63 Query: 119 KAVRYSNVVINLVGRDYETKNFKYND----VHVDGVRRIARICREEGVERFIHLSYLNAE 174 V + VINLVG + Y HV+ ++I C V +H+S L A Sbjct: 64 HLVSGVDAVINLVGILHSRSGSPYGRDFARAHVELPQKIVAACHAARVPHLVHVSALGAS 123 Query: 175 EHPKPLVLKKPSAWKISKYLGECAVRE--EYPTATIIRASDIYGSEDRFLRSLVNKMRSH 232 PS + SK GE A+R + P T++R + ++G D F +L ++ + Sbjct: 124 PDG-------PSEYLRSKAAGEAAIRASGDAPAWTVLRPAVMFGRGDHFT-NLFARLATR 175 Query: 233 SNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYK 292 L+PL G QPV V DVA I RD E ++ GP+ Y L +LV++ + Sbjct: 176 FPLLPLA--GARARFQPVHVEDVAAVICRCLRDPAAIGETFELAGPRVYTLRELVEYISE 233 Query: 293 L 293 L Sbjct: 234 L 234 >UniRef50_A0L6A2 Cluster: NAD-dependent epimerase/dehydratase; n=1; Magnetococcus sp. MC-1|Rep: NAD-dependent epimerase/dehydratase - Magnetococcus sp. (strain MC-1) Length = 294 Score = 75.8 bits (178), Expect = 2e-12 Identities = 49/173 (28%), Positives = 86/173 (49%), Gaps = 9/173 (5%) Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 175 S+ A+ VI+LVG E ++ + ++H G + + ++ GV+RF+H+S L Sbjct: 54 SLQTAMEGVTCVIHLVGILAEQRHRSFEEIHHQGTLNVLQAAKQAGVKRFLHMSSLGTRA 113 Query: 176 HPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNL 235 + + + SK+ ECAVRE TI R S I+G D F+ +R S + Sbjct: 114 N-------AVARYHQSKWQAECAVRESGLDYTIFRPSVIFGPGDNFVNQFARMIR-FSPM 165 Query: 236 MPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVD 288 +P+ +G + QP+ V DVA+ A D T + Y+ GP++ ++++ Sbjct: 166 VPILGDGQNRM-QPIAVGDVARCFAIALTDRQTLGQTYELGGPQQLTFQEIME 217 >UniRef50_A7BKW7 Cluster: NAD-dependent epimerase/dehydratase; n=1; Beggiatoa sp. SS|Rep: NAD-dependent epimerase/dehydratase - Beggiatoa sp. SS Length = 263 Score = 74.9 bits (176), Expect = 3e-12 Identities = 72/243 (29%), Positives = 119/243 (48%), Gaps = 26/243 (10%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQL-ILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 117 + G TGFVG+ + N+L K+G Q+ +L R + + + L V L ++L T Y D+ + Sbjct: 6 LLGGTGFVGKQLANRLFKMGWQVRVLTRRRE--EHRELLVLPTL-ELLSTNY---DQAQL 59 Query: 118 AKAVRYSNVVINLVG----RDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA 173 + R +VVINLVG ++ K F+ HV+ +++ C+E ++R +H+S LNA Sbjct: 60 NEQTRGCDVVINLVGILNESGHDGKGFQ--KAHVELPQKVIAACQENKIKRLLHISALNA 117 Query: 174 EEHPKPLVLKKPSAWKISKYLGECAVREEYPT-ATIIRASDIYGSEDRFLRSLVNKMRSH 232 + +K S + +K E + T R S I+G D FL V+ +R Sbjct: 118 D------ATQKNSHYLRTKGEAEDLIHAVSDVHVTSFRPSVIFGEGDSFLNRFVSMLRVP 171 Query: 233 SN--LMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWF 290 S ++P + LA PV+V+DV + ++ + E Y G Y L +LV + Sbjct: 172 SPIFMLPSFDAKLA----PVWVNDVVRAMLEVVENPQYDGERYNFCGGSVYTLQELVAYL 227 Query: 291 YKL 293 KL Sbjct: 228 AKL 230 >UniRef50_Q2Y682 Cluster: NAD-dependent epimerase/dehydratase; n=1; Nitrosospira multiformis ATCC 25196|Rep: NAD-dependent epimerase/dehydratase - Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849) Length = 312 Score = 74.5 bits (175), Expect = 4e-12 Identities = 66/231 (28%), Positives = 102/231 (44%), Gaps = 19/231 (8%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 +FG +GFVG+++ N L L +P R + +R K ++ + D+ + Sbjct: 8 IFGGSGFVGKHLANLLTNREIYLRIPTR----NYERAKELLEIPTTDLIEADIYDDRDLD 63 Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 178 + + + VINLVG ++ VHV+ ++I C+ G+ R +H+S L A Sbjct: 64 RLLLGIDAVINLVG----VLQGDFHAVHVELPQKIIAACKRNGITRILHMSALKAGPG-- 117 Query: 179 PLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPL 238 +PS + SK GE VR AT+ R S I+G D S +N L L Sbjct: 118 -----QPSEYLRSKGEGEQIVRTSGMDATVFRPSVIFGPGD----SSINLFARLGRLPVL 168 Query: 239 YKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDW 289 QP+FV DV Q + + T Y GPK Y L +LV++ Sbjct: 169 PLASPHAKFQPIFVMDVVQAFALSLDEPRTFGRSYDLCGPKCYSLRELVEY 219 >UniRef50_Q1K3T7 Cluster: NAD-dependent epimerase/dehydratase; n=1; Desulfuromonas acetoxidans DSM 684|Rep: NAD-dependent epimerase/dehydratase - Desulfuromonas acetoxidans DSM 684 Length = 297 Score = 74.5 bits (175), Expect = 4e-12 Identities = 63/230 (27%), Positives = 101/230 (43%), Gaps = 17/230 (7%) Query: 61 GCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKA 120 G TGFVG +V L G + R + L QV + + + +A Sbjct: 7 GATGFVGHHVIQALLLNGHTVRCLVR------KPTPSLTSLVQVETVQGDITNPAELKQA 60 Query: 121 VRYSNVVINLVG--RDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 178 + + +I+LVG R + + + +HV+ R I E G++R++H+S A Sbjct: 61 MSDCDAIIHLVGIIRAFPQRGITFEKLHVEATRNIITAAAEAGIDRYLHMSANGASPDC- 119 Query: 179 PLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPL 238 P A+ +K+ E VR+ T TI R S I+G + F R L+ ++R ++P+ Sbjct: 120 ------PEAYGATKWRAEELVRQSRLTWTIFRPSLIFGPDGEFTRMLIQQLR-FLPMIPI 172 Query: 239 YKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVD 288 +G + PV V DVA G NA ++Y GP DL+D Sbjct: 173 IGDGHYQL-SPVNVDDVALGFANALSSPQAIGKIYHCCGPDTCSYNDLID 221 >UniRef50_Q1WMR0 Cluster: Putative nucleoside-diphosphate-sugar epimerase; n=1; Coprinellus disseminatus|Rep: Putative nucleoside-diphosphate-sugar epimerase - Coprinellus disseminatus Length = 330 Score = 74.1 bits (174), Expect = 6e-12 Identities = 57/178 (32%), Positives = 94/178 (52%), Gaps = 16/178 (8%) Query: 115 ESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 174 E++ A ++ V++LVG Y K + + G +A+ ++ G R IH+S + A Sbjct: 75 ETLTPAFEGAHTVVSLVGVMYG-KPADFERIQWRGAENVAKAAQKAGA-RLIHISAIGA- 131 Query: 175 EHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSN 234 +P + S W+ +K LGE AVR +PTATIIR S ++G ED F +K+ Sbjct: 132 -NPSSDI----SYWR-TKGLGEEAVRSVHPTATIIRPSLVFGPEDDFFNRF-SKLSKFLP 184 Query: 235 LMPLYKNGLATVKQPVFVSDVAQGIVNAARDD-----DTKCEVYQAVGPKRYLLADLV 287 +P++ G A + QPV+V D+A+ I +R D + ++ +A GP+ Y DL+ Sbjct: 185 FLPVFGGGQA-MFQPVYVDDIAKAIEVMSRGDPEVEKEISGKIIEAGGPRVYTYYDLM 241 >UniRef50_Q3JE30 Cluster: NAD-dependent epimerase/dehydratase; n=2; Chromatiales|Rep: NAD-dependent epimerase/dehydratase - Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) Length = 320 Score = 73.7 bits (173), Expect = 8e-12 Identities = 61/238 (25%), Positives = 106/238 (44%), Gaps = 11/238 (4%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 + G TGFVGR++ + L + G ++ + R QR + L + + D +A Sbjct: 8 ILGGTGFVGRWLSSHLVEQGYKVRVLTR----HWQRHRDLLVLPGLRLMETDVYDPAQLA 63 Query: 119 KAVRYSNVVINLVG--RDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEH 176 VINL+G + + VH D ++A+IC + G++R +H+S LNA+ + Sbjct: 64 AQFNGCQSVINLIGILNEKGRNGHGFRQVHADLPEKVAQICLDTGIKRLLHMSALNADAN 123 Query: 177 PKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLM 236 + ++ L A+ + TI + S I+G D F + ++ + Sbjct: 124 QGASYYLRSKGEGENRVL---ALARQGLEVTIFQPSVIFGPGDSFFNRFGSLLKLSPFIF 180 Query: 237 PLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLM 294 PL PV+V DVA+ A D + + Y+ GPK Y L LV++ K++ Sbjct: 181 PLACPEARLT--PVYVGDVARAFARALSDKEDFSQSYELCGPKIYTLKQLVEYTAKVL 236 >UniRef50_Q7NWF7 Cluster: Probable NADH-ubiquinone oxidoreductase; n=1; Chromobacterium violaceum|Rep: Probable NADH-ubiquinone oxidoreductase - Chromobacterium violaceum Length = 313 Score = 72.9 bits (171), Expect = 1e-11 Identities = 59/228 (25%), Positives = 103/228 (45%), Gaps = 16/228 (7%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 + G +GF+GR++ +L G ++ + R R+ +L + H D +A Sbjct: 8 LIGGSGFIGRHLAAQLASRGHRITIASRRTGLPDFRVLPSAEL---VSADIH--DPGQLA 62 Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 178 + + V+++VG + ++ ++ H +I CR +GV R +H+S L A + Sbjct: 63 GLIAGHDAVVSMVGILHGSRA-QFEKAHAQLPEKIVDACRRQGVRRLVHVSALGAAQDA- 120 Query: 179 PLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPL 238 PS ++ +K LGE AV TI+R S ++G D FL ++ ++PL Sbjct: 121 ------PSDYQQTKALGELAVESSGLDWTILRPSVVFGHGDAFLNMFAG-LQKRLPVLPL 173 Query: 239 YKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADL 286 G PV+V DVA+ + +T+ GP+ Y LA L Sbjct: 174 --AGAGCKMAPVWVEDVARAVCECLARKETEGRKLDLAGPETYTLAQL 219 >UniRef50_Q39C42 Cluster: NAD-dependent epimerase/dehydratase; n=30; Burkholderiales|Rep: NAD-dependent epimerase/dehydratase - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 319 Score = 72.5 bits (170), Expect = 2e-11 Identities = 71/238 (29%), Positives = 106/238 (44%), Gaps = 25/238 (10%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 + G TGF+G + N L + G Q+ + R + A+ L++ V LD ++A Sbjct: 8 LLGGTGFIGSRLVNALIESGKQVRIGTRRRDH-ARHLQML----PVEVVELEALDTRTLA 62 Query: 119 KAVRYSNVVINLVGRDYETKNFKYND----VHVDGVRRIARICREEGVERFIHLSYLNAE 174 + V ++ INLVG + + Y HV +A C E GV R +H+S L A+ Sbjct: 63 RFVAGAHAAINLVGVLHGGRGTPYGPGFERAHVTLPAALATACTEVGVRRVLHMSALGAD 122 Query: 175 EHPKPLVLKKPSAWKISKYLGECAVREEYPT----ATIIRASDIYGSEDRFLRSLVNKMR 230 H S ++ SK GE A+ T TI R S ++G D FL + N R Sbjct: 123 SH-------GASMYQRSKGDGEAALHAIAATDSLALTIFRPSVVFGPGDAFLNTFANLQR 175 Query: 231 SHSNLMPLYKNGLATVK-QPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287 S +P+ + + QPVFV DV + VN + + Y+ GP Y L LV Sbjct: 176 S----VPVLPLAMPDARFQPVFVGDVVRAFVNTLDLAASHGKTYELGGPTVYTLEQLV 229 >UniRef50_A3ES38 Cluster: Putative nucleoside-diphosphate-sugar epimerase; n=1; Leptospirillum sp. Group II UBA|Rep: Putative nucleoside-diphosphate-sugar epimerase - Leptospirillum sp. Group II UBA Length = 299 Score = 71.3 bits (167), Expect = 4e-11 Identities = 49/181 (27%), Positives = 90/181 (49%), Gaps = 9/181 (4%) Query: 108 PYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIH 167 P ++ D S+A ++V++L G ETK+ Y +HVDG R + + V R I+ Sbjct: 49 PGNVTDRGSLAPVFDGVDMVLHLTGILAETKSQSYEAIHVDGTRNVLDASKAGRVSRIIY 108 Query: 168 LSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVN 227 LS + A + S + +K E ++ TI R S ++G +D+FL +L Sbjct: 109 LSAIGASRTAR-------SRYHRTKAEAEDLLKNSGMDVTIFRPSVVFGKDDKFL-NLFA 160 Query: 228 KMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287 M +++PL +G + V PV+V+D+ + ++ + + +T YQ G + Y +L+ Sbjct: 161 GMGKTLHVLPLIGDGQSRV-HPVWVNDLVESVLESMKQPETVGRTYQMGGCRIYTYHELM 219 Query: 288 D 288 + Sbjct: 220 E 220 >UniRef50_Q560L2 Cluster: Putative uncharacterized protein; n=2; Filobasidiella neoformans|Rep: Putative uncharacterized protein - Cryptococcus neoformans (Filobasidiella neoformans) Length = 375 Score = 71.3 bits (167), Expect = 4e-11 Identities = 49/150 (32%), Positives = 80/150 (53%), Gaps = 10/150 (6%) Query: 117 IAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEH 176 + KA + ++ V++L G + + + DG RR+ EEGV R + +S + A+ Sbjct: 84 LRKAFKGASAVVSLAGL-LVGNDKQMKALQEDGARRVGEAASEEGVGRVVGVSAIGAD-- 140 Query: 177 PKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLM 236 L+ +A+ +K GE A+RE +PTATIIR S ++G D F S + + + Sbjct: 141 -----LRGVTAYWRTKAKGEDAIREYHPTATIIRPSLLFGPGDSFF-SRFATLAKYLPFL 194 Query: 237 PLYKNGLATVKQPVFVSDVAQGIVNAARDD 266 P++ G+ T QPV+V DVA+ + RDD Sbjct: 195 PVFGGGI-TRFQPVYVGDVARAVEICCRDD 223 >UniRef50_Q67SF4 Cluster: Putative NADH-ubiquinone oxidoreductase; n=1; Symbiobacterium thermophilum|Rep: Putative NADH-ubiquinone oxidoreductase - Symbiobacterium thermophilum Length = 303 Score = 70.1 bits (164), Expect = 9e-11 Identities = 84/319 (26%), Positives = 133/319 (41%), Gaps = 38/319 (11%) Query: 56 VATVFGCTGFVGRYVCNKLGKIGTQLIL------PYRGDFYDAQRLKVCGDLGQVLFTPY 109 V V G TGF+G Y+ +L + G ++I+ RG D ++ GD+ Sbjct: 3 VVLVAGGTGFIGSYIVRRLTQDGHRVIVMSRDPGKARGRVPDGVEVRA-GDVTDGATLGP 61 Query: 110 HLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLS 169 L E + AV++ N + R + Y V +G R+ R+ GV RF+++S Sbjct: 62 ALAGAEIVVCAVQFPNHPVENPRRGHT-----YIRVDGEGTVRLVGAARKAGVSRFVYIS 116 Query: 170 YLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKM 229 E KP W +K + E A+RE TI R S +YG EDR L NK Sbjct: 117 GAGTREGQT-----KP--WFRAKLMAEKAIRESGIPYTIFRPSWVYGPEDRSL----NKF 165 Query: 230 RSHSNLMPLYK--NGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287 + + L+P T QP++V D+A + + R Y GP+ + +++ Sbjct: 166 ATFARLLPFVPVIGSGRTRVQPLYVEDLADAVAASLRTGAALNRTYDIGGPQELTMDEII 225 Query: 288 DWFYKLMRKDEKWGGYIRYDMKYDPILPLKVAL-VNAISPAYPLGNLHWEGIEREATSDN 346 +M + R + + P +K A P PL + + E DN Sbjct: 226 RTMLWVMGR--------RRPLLHSPAWLMKAAAWPLQFLPTPPLSPGAVDFVLMEEPVDN 277 Query: 347 VVIGVPTLEDLGVTLTHME 365 + L+DLG+TLT +E Sbjct: 278 GQV----LQDLGLTLTPLE 292 >UniRef50_Q7NF91 Cluster: Gll3635 protein; n=1; Gloeobacter violaceus|Rep: Gll3635 protein - Gloeobacter violaceus Length = 298 Score = 69.3 bits (162), Expect = 2e-10 Identities = 55/228 (24%), Positives = 102/228 (44%), Gaps = 14/228 (6%) Query: 61 GCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKA 120 G TGF+G + L + G + R D LK +V HL D+ S+ +A Sbjct: 6 GATGFIGSHTARTLRERGLSVRALVRSGA-DTSALKAL----EVDLVVGHLDDKASLVRA 60 Query: 121 VRYSNVVINLVGRDYETK-NFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKP 179 + +++LVG E + +HV+G R + E GV +F+++S + + +P Sbjct: 61 CTGVDAIVHLVGIIRELPPTVTFERIHVEGTRNLLAAATEAGVRKFVYISAIGS----RP 116 Query: 180 LVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLY 239 + + + +K+ E VR T I+R S ++G D F+ L N + +P+ Sbjct: 117 DAIAR---YHQTKWATEALVRSSGLTWVILRPSVVFGPGDEFINLLANDLVRKPPFIPVI 173 Query: 240 KNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287 G + QP++V D+A+ I + + GP++ L +++ Sbjct: 174 GPGTNKL-QPLWVKDLAEVIARCTTSSSFDGRILEVGGPEQLSLHEIL 220 >UniRef50_Q476T1 Cluster: NAD-dependent epimerase/dehydratase:3-beta hydroxysteroid dehydrogenase/isomerase:dTDP-4-dehydrorhamnose reductase; n=7; Burkholderiaceae|Rep: NAD-dependent epimerase/dehydratase:3-beta hydroxysteroid dehydrogenase/isomerase:dTDP-4-dehydrorhamnose reductase - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 340 Score = 67.3 bits (157), Expect = 7e-10 Identities = 54/167 (32%), Positives = 81/167 (48%), Gaps = 16/167 (9%) Query: 126 VVINLVGRDYETKNFKYND----VHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPLV 181 +V+NLVG + + Y HV+ V ++ C GV R +H+S L A+ Sbjct: 93 IVVNLVGVLHGERGDPYGPEFAAAHVEIVEQVVGSCLRTGVRRLLHMSALGADS------ 146 Query: 182 LKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKN 241 + PS ++ SK GE VR+ T+ R S ++G +D FL +L M+ + ++PL Sbjct: 147 -RGPSMYQRSKGDGERLVRDSGLDWTVFRPSVVFGPDDHFL-NLFAHMQEIAPVVPL--- 201 Query: 242 GLATVK-QPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287 A + QP++V DV Q VNA T Y GP Y L +LV Sbjct: 202 ACAHARFQPIYVLDVVQAFVNAMVTPATIGHGYDLGGPTVYTLEELV 248 >UniRef50_Q746J9 Cluster: NADH-ubiquinone oxidoreductase 39 kDa subunit/NADH dehydrogenase; n=2; Thermus thermophilus|Rep: NADH-ubiquinone oxidoreductase 39 kDa subunit/NADH dehydrogenase - Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) Length = 287 Score = 66.5 bits (155), Expect = 1e-09 Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 26/231 (11%) Query: 59 VFGCTGFVGRYVCNKLGKIG-TQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 117 V G TGFVGR V L G T L+L R + V GD+ + + D E Sbjct: 5 VVGGTGFVGREVVRLLLARGHTPLVLARRSRPLPEGAVLVEGDIAR------EVPDLEG- 57 Query: 118 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 177 A+A Y +I G+ + VHV+GVR + R GV R +H+S L A Sbjct: 58 AEAAIYLAGIIRERGQTFRA-------VHVEGVRNLLRAMERAGVGRLLHMSALGA---- 106 Query: 178 KPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFL-RSLVNKMRSHSNLM 236 +P + PS + +K GE VR+ + I R S I+G D F R L + + + Sbjct: 107 RP---EAPSRYHRTKAEGEALVRQSGLSHAIFRPSLIFGPGDEFFGRVLRGLVCAPLPFV 163 Query: 237 PLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287 PL +G +PV+V DVA+ V A + Y VGPK Y +L+ Sbjct: 164 PLIGDG-GFPFRPVYVGDVAEAFVGAL--ERGLEGTYDLVGPKEYSFRELL 211 >UniRef50_Q31J38 Cluster: NAD-dependent epimerase/dehydratase; n=1; Thiomicrospira crunogena XCL-2|Rep: NAD-dependent epimerase/dehydratase - Thiomicrospira crunogena (strain XCL-2) Length = 323 Score = 66.5 bits (155), Expect = 1e-09 Identities = 69/251 (27%), Positives = 116/251 (46%), Gaps = 23/251 (9%) Query: 54 GIVATVFGCTGFVGRYVCNKLGKIGTQL-ILPYRGDFYDAQRLKVCGDLGQVLFTPYHLL 112 G V G TGF+GR V N+L K G ++ ++ R + + L L Q+ LL Sbjct: 3 GNKVVVLGGTGFIGRSVVNELSKSGYEISVVVRRPERFRDYMLYKNTKLVQI----DSLL 58 Query: 113 DEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGV-RRIARICREEGVERFIHLSYL 171 D E + KA ++VV+NL D K ++ + V ++I + G++R + LS + Sbjct: 59 DSEGLKKAFMGTDVVVNLTA-DLTAKTEAVSEKDIVAVNQQIKKAVESAGIKRVVALSQI 117 Query: 172 NAEEHPKPLVLKKPSAWKISKYLGEC-AVREEYPTA--TIIRASDIYGSEDRFLRSLVNK 228 A+ + + W + LGE A+ A TI+RA + G D + + Sbjct: 118 GADAN------NARNNWLYN--LGESDAIMHTISCAQVTILRAGLLLGEGD----EVATR 165 Query: 229 MRSHSNLMPLYKNGLATVK-QPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287 ++ NL P+ A+V QP+ V D A+ +V + +D + + VG +R L DL Sbjct: 166 FKNQLNLFPVLPVANASVAVQPLSVKDFAKALVLSIKDTTLFGKKVEVVGEERMALKDLA 225 Query: 288 DWFYKLMRKDE 298 +M+KD+ Sbjct: 226 SLVRDMMQKDD 236 >UniRef50_Q74G63 Cluster: NADH dehydrogenase subunit, putative; n=6; Desulfuromonadales|Rep: NADH dehydrogenase subunit, putative - Geobacter sulfurreducens Length = 294 Score = 64.1 bits (149), Expect = 6e-09 Identities = 64/242 (26%), Positives = 112/242 (46%), Gaps = 23/242 (9%) Query: 59 VFGCTGFVGRYVCNKLGKIG--TQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEES 116 V G TGFVG +V L + G +L++ R + +A +V GD+ + ++ Sbjct: 5 VTGGTGFVGGHVRRALLERGHSLRLLVHQRSEGVEAGIEQVEGDVTR----------PDT 54 Query: 117 IAKAVRYSNVVINLVG--RDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 174 A AV + +NLVG R++ + + +HV+ R + R G+ R + +S L Sbjct: 55 FAGAVAGCDATVNLVGIIREFPGRGITFEKLHVEATRNVVEAARAAGIRRHLQMSALAT- 113 Query: 175 EHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSN 234 +P +A+ +K+ E VR+ TI R S I+G + F+ L +R Sbjct: 114 ---RP---DATAAYHRTKWRAEEVVRQSELDWTIFRPSLIFGPKGAFVDMLAGFVRRFP- 166 Query: 235 LMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLM 294 +P+ +G + QPV V DVA+ A +T + Y+ GP R +++D +++ Sbjct: 167 AVPVVGDGTYRL-QPVSVDDVARCFALALDMPETFGQTYELCGPDRLTYNEVLDIIGRVL 225 Query: 295 RK 296 K Sbjct: 226 GK 227 >UniRef50_Q1IZY4 Cluster: NAD-dependent epimerase/dehydratase; n=2; Deinococcus|Rep: NAD-dependent epimerase/dehydratase - Deinococcus geothermalis (strain DSM 11300) Length = 309 Score = 62.5 bits (145), Expect = 2e-08 Identities = 81/322 (25%), Positives = 132/322 (40%), Gaps = 41/322 (12%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 V G TGFVG+ + +L G + R G L + D S+ Sbjct: 18 VTGATGFVGQALVRELVSRGHTVFAGSRSG----------GALPGATGLRLDVTDPGSVL 67 Query: 119 KAVRYSN--VVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEH 176 +AV ++ V++LVG E + VHV+G R + + R++H+S L A+E Sbjct: 68 RAVGEADPEAVVHLVGIIQEEGTQTFRRVHVEGTRNVLAATPRQA--RYLHMSALGADE- 124 Query: 177 PKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLM 236 S + SK E VRE TI R S I+G D F ++ ++ + + ++ Sbjct: 125 ------ASASRYSASKGEAERLVRESGLAWTIFRPSLIFGVGDDFFGRVLRELVTAAPIV 178 Query: 237 PLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMRK 296 P +G + PV V DVA A +T Y GP+ + F L+ + Sbjct: 179 PQIGDGHFPFR-PVSVEDVALAFAGALERPETAGHTYALTGPEEFT-------FRALLEE 230 Query: 297 DEKWGGYIRYDMKYDPILPLKVALVNAISPAYPLGNLHWEGIERE----ATSDNVVIGVP 352 ++ G R PI+P+ +AL+N P L L I R+ + N P Sbjct: 231 EQAALGQRR------PIVPVPLALMNLAVPLMQL--LPHPPITRDQYLMLKAGNTAPNEP 282 Query: 353 TLEDLGVTLTHMEDQVPWELKP 374 G+ + + +++P L+P Sbjct: 283 ARTVFGLPMHRLRERLPEILRP 304 >UniRef50_Q9HNV3 Cluster: NADH dehydrogenase/oxidoreductase-like protein; n=5; Halobacteriaceae|Rep: NADH dehydrogenase/oxidoreductase-like protein - Halobacterium salinarium (Halobacterium halobium) Length = 303 Score = 62.1 bits (144), Expect = 2e-08 Identities = 64/242 (26%), Positives = 102/242 (42%), Gaps = 21/242 (8%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 V G TGF+G ++C +L G + R A V +G V +E++A Sbjct: 13 VTGGTGFIGTHLCRELDDRGHDVTAFAREPADAALPADVTRIVGDVTV-------KETVA 65 Query: 119 KAVRYSNVVINLVGRDYETK----NFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 174 A+ + V+NLV K + ++ DVH+ G + E GVE + LS L+A+ Sbjct: 66 NAIDGHDAVVNLVALSPLFKPSGGDSRHLDVHLGGTENVVAAASEAGVEYILQLSALDAD 125 Query: 175 EHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSN 234 P+A+ +K E AVR TI+R S ++G F+ + Sbjct: 126 P-------TGPTAYLRAKGRAEEAVRSSDLHHTIVRPSVVFGDGGEFVPFTKQLTTPYVT 178 Query: 235 LMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLM 294 +P G A+ QP++V D+ + +A + E Y GP LAD+ Y+ Sbjct: 179 GLP---GGGASKFQPIWVGDLVPMLADALGTEAHWGETYDIGGPDVLTLADVTRMAYRAA 235 Query: 295 RK 296 K Sbjct: 236 GK 237 >UniRef50_Q3SGD6 Cluster: Nucleoside-diphosphate-sugar epimerases; n=1; Thiobacillus denitrificans ATCC 25259|Rep: Nucleoside-diphosphate-sugar epimerases - Thiobacillus denitrificans (strain ATCC 25259) Length = 345 Score = 59.7 bits (138), Expect = 1e-07 Identities = 75/273 (27%), Positives = 125/273 (45%), Gaps = 47/273 (17%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQL-ILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 117 V G +GFVG ++ ++L G + +L R + A+ L + + +V+ H DE + Sbjct: 8 VLGGSGFVGTHLVSQLAARGLNVRVLSRRRE--TAKELILLPTV-EVVEADVH--DEHEL 62 Query: 118 AKAVRYSNVVINLVGRDYETKNFK----------YNDVHVDGVRRIARICREEGVERFIH 167 + R + VINLVG +E K + + VH++ R+I E V R +H Sbjct: 63 VRHFRGMDAVINLVGILHEGKVGRADLPSARRGDFQRVHIELPRKIVHAMGEANVHRLLH 122 Query: 168 LSYLNAEEHPKPLVLKKPSAWKISKYLGECAVRE------EYP---------------TA 206 +S L A+ + + SA++ SK +GE VRE E+ Sbjct: 123 MSALGADPNSR-------SAYQRSKGIGEALVREAGRRHVEHENWYLNGPKFIHGYGLNV 175 Query: 207 TIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDD 266 T+ R S I+G D FL S+ ++ ++PL +G A PV V DVA+ ++ + Sbjct: 176 TVFRPSVIFGRGDSFL-SMFARLLKRFPVLPL-GSGDARF-APVHVEDVARAFADSLDNV 232 Query: 267 DTKCEVYQAVGPKRYLLADLVDWFYKLMRKDEK 299 T E Y+ GP+ Y L +LV + ++ K + Sbjct: 233 ATFGETYELCGPRAYTLQELVSYVGEVTGKPRR 265 >UniRef50_UPI00015BC9D3 Cluster: UPI00015BC9D3 related cluster; n=1; unknown|Rep: UPI00015BC9D3 UniRef100 entry - unknown Length = 303 Score = 56.8 bits (131), Expect = 9e-07 Identities = 70/240 (29%), Positives = 104/240 (43%), Gaps = 26/240 (10%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 V G TGFVG+YV L K L R KV V F DEES+ Sbjct: 5 VAGGTGFVGKYVVEALEKSTHSYKL--------LTRKKVSKPHIVVDF-----FDEESLK 51 Query: 119 KAVRYS--NVVINLVGRDYE--TKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 174 KA +V+INL+G E +K + ++H + + + +E G++ IH+S L Sbjct: 52 KAFEQEKPDVLINLIGILVEEPSKGITFENIHYLIPKNLYTVAKEYGIKHIIHMSALGVS 111 Query: 175 EHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSN 234 E + PS + +K L E + TIIR S I G E R + L + + + Sbjct: 112 E-------EAPSMYHHTKLLAEKFLMSLGIDYTIIRPSLIIGPEQRLFKDL-DFFGKYFH 163 Query: 235 LMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLM 294 +M + L+ PV V DVA V A D + K ++ + G K L+ +KL+ Sbjct: 164 IM-AHPGILSYYFAPVDVRDVAFVFVKAIDDPNLKNKIIELCGKKPVSFDKLLKDSFKLL 222 >UniRef50_Q4UMY6 Cluster: Putative oxidoreductase protein; n=15; Rickettsia|Rep: Putative oxidoreductase protein - Rickettsia felis (Rickettsia azadi) Length = 431 Score = 54.4 bits (125), Expect = 5e-06 Identities = 52/232 (22%), Positives = 108/232 (46%), Gaps = 15/232 (6%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHL-LDEESI 117 + G GF+G Y+ +L K ++I R D + K +V++ +++ L +S Sbjct: 5 ITGANGFIGSYITAELLKNNYEVICCVR----DVESTKKKFPTAEVIYCDFNIDLTPQSW 60 Query: 118 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 177 + ++VIN+ G + +VHV+G + + + C V+R IH+S L ++ Sbjct: 61 INRLNNIDIVINVSGVLASSHANNIENVHVNGPKALFKACTLTNVKRIIHISALGIDD-- 118 Query: 178 KPLVLKKPSAWKISKYLGECAVRE-EYPTATIIRASDIYGSEDRFLRSLV-NKMRSHSNL 235 +K +A+ ++K E +++ E I++ S +Y S SL + + Sbjct: 119 -----EKNTAYALTKKATEAYLQKLENIDWVILQPSLVYASGCYGGTSLFRGALATLPYF 173 Query: 236 MPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287 +PL +GL QP+ + D+ + I++ + ++ + VGP + D++ Sbjct: 174 IPLIGDGLQQF-QPIHIDDLTKVIIHCIEREGKIHKLLKIVGPDIVTMKDIL 224 >UniRef50_Q0LC55 Cluster: NAD-dependent epimerase/dehydratase; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: NAD-dependent epimerase/dehydratase - Herpetosiphon aurantiacus ATCC 23779 Length = 308 Score = 54.4 bits (125), Expect = 5e-06 Identities = 60/248 (24%), Positives = 106/248 (42%), Gaps = 20/248 (8%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 V G TG+VG + KL + + + R AQ+L G V + D ES+ Sbjct: 4 VTGGTGYVGSRLIEKLRQRPEPVRVLVRTP-EKAQKLVA----GNVSIVKGDVTDPESLI 58 Query: 119 KAVRYSNVVINLVGRDYETKN-FKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 177 A++ + VI+LV E + ++ + + GV+RF+H+S L P Sbjct: 59 AAMKGVSTVIHLVAIIRERSGGISFERMNYQATVNVVDAAKAAGVKRFLHMSALGVVNDP 118 Query: 178 KPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMR-----SH 232 + + ++ KY+ + T+ + S I+G D F+ +L + +R + Sbjct: 119 NLPYMD--TKFRAQKYVEASGL-----DWTVFQPSVIFGEGDEFINTLADLVRRPLMIAP 171 Query: 233 SNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDW-FY 291 + +P+ +G T QPV+ DV + D T ++YQ GP+ ++D Sbjct: 172 APFVPVVGDG-KTKFQPVWRDDVIDAFIKVLDDHSTIGQIYQLGGPEALTYEQMLDLIMQ 230 Query: 292 KLMRKDEK 299 KL +K K Sbjct: 231 KLGKKRSK 238 >UniRef50_O54156 Cluster: Oxidoreductase; n=1; Streptomyces coelicolor|Rep: Oxidoreductase - Streptomyces coelicolor Length = 347 Score = 53.6 bits (123), Expect = 9e-06 Identities = 61/234 (26%), Positives = 101/234 (43%), Gaps = 23/234 (9%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 V G +GF+G ++ ++L + G ++ + R + R G QV T L D +S+ Sbjct: 18 VTGASGFIGGHLVHRLAERGHRVRVLARST---SDRAAFAGAAAQV--TVGDLGDTDSLR 72 Query: 119 KAVRYSNVVINLVGRDYETKNF-KYNDVHVDGVRRIARICREEG-VERFIHLSYLNAEEH 176 +A V N G + + ++ V+VDG R + E G VER +HLS + + Sbjct: 73 RATTGIRHVYNCAGLSADWGPWDRFRAVNVDGARNLVEAAHEAGTVERLVHLSTTDVYGY 132 Query: 177 PKPLVLKKPSAWKI------SKYLGECAV-----REEYPTATIIRASDIYGSEDR-FLRS 224 P+ ++ + I SK LGE AV R P T++R +YG + F+ Sbjct: 133 PERPCDERTAPRDIGLPYNRSKMLGEAAVWAAAERTGQPV-TVVRPVSVYGPGSKDFVIE 191 Query: 225 LVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGP 278 + N + + Y G ++VS+ GI+ AA + T Y P Sbjct: 192 IANLLLGKQMV---YIRGGRVPAGLLYVSNAVDGIIAAATGEHTAGRAYNLRDP 242 >UniRef50_A0YYK8 Cluster: Oxidoreductase; n=1; Lyngbya sp. PCC 8106|Rep: Oxidoreductase - Lyngbya sp. PCC 8106 Length = 343 Score = 53.2 bits (122), Expect = 1e-05 Identities = 56/239 (23%), Positives = 107/239 (44%), Gaps = 21/239 (8%) Query: 54 GIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLD 113 G A V G TGF G + KL + G +++ R L+ L + + + D Sbjct: 11 GSRALVTGATGFTGSLLVRKLVQQGVEVVAIAR----PTSNLEPFEGL-NIEWLRGDVFD 65 Query: 114 EESIAKAVRYSNVVINLVG--RDYETKNFKYNDVHVDGVRRIARIC-REEGVERFIHLSY 170 E I KA++ N + ++V RD + K+ Y +VHV + +A+ +E +RF+H+S Sbjct: 66 ENLINKAIQGVNYIFHMVTPFRDPKLKDIGYFNVHVLSTQLLAKAALKEPNFKRFVHVST 125 Query: 171 LNAEEH------PKPLVLKKPSAWKISKYLGECAVREEYPTA----TIIRASDIYGSEDR 220 + H + +K ++ +K E +R+ P A ++R + IYG D+ Sbjct: 126 IGVHGHIEQPPADETYRMKPGDIYQETKVEAELWIRDFAPKAGLSFAVVRPAGIYGPGDK 185 Query: 221 FLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPK 279 L + + + +P+ +G + + + V D+ ++ AA + EV+ P+ Sbjct: 186 RLLKIFQMV--NKKWVPVIGDG-SNLYHFIHVDDLTNFMICAATHPKAEAEVFICGSPE 241 >UniRef50_Q67KJ4 Cluster: Putative oxidoreductase; n=1; Symbiobacterium thermophilum|Rep: Putative oxidoreductase - Symbiobacterium thermophilum Length = 342 Score = 52.8 bits (121), Expect = 2e-05 Identities = 65/238 (27%), Positives = 104/238 (43%), Gaps = 23/238 (9%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVL-FTPYHLLDEESI 117 V G TGF+G + L + G Q+ + R + V G L L L DE S+ Sbjct: 4 VTGATGFIGSQLVPHLVEQGRQVRILVRSR---QKAEAVFGPLCAALEVAEGDLGDEASL 60 Query: 118 AKAVRYSNVVINLVGR-DYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA--- 173 A+A + V +L R +++ + ++V+G RR+ C GV+R +H+S + A Sbjct: 61 ARAAAGVDRVYHLASRINFQGSLRRMRAINVEGTRRLLDACAAAGVKRVVHMSSIAAGGP 120 Query: 174 ---EEHPKPLVLKK-------PSAWKISKYLGE---CAVREEYPTATIIRASDIYGSEDR 220 +E+ + + P A+ I+K E + +E ++R S ++G D Sbjct: 121 AVKDENGRYRARTEEDEAAPLPDAYGITKLEQERLALSYQERGLEVVVVRPSAVFGPGDP 180 Query: 221 FLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGP 278 + + M + L P Y V VFV DV +G V AA + EVY VGP Sbjct: 181 DGMNTLIWMVKNGRL-PFYLGSGQAVVNLVFVRDVVRGTV-AAMERGRPGEVYHLVGP 236 >UniRef50_Q3A8K9 Cluster: Nucleoside-diphosphate-sugar epimerases; n=1; Pelobacter carbinolicus DSM 2380|Rep: Nucleoside-diphosphate-sugar epimerases - Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1) Length = 297 Score = 52.8 bits (121), Expect = 2e-05 Identities = 46/184 (25%), Positives = 83/184 (45%), Gaps = 11/184 (5%) Query: 115 ESIAKAVRYSNVVINLVG--RDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLN 172 ES+ A+ V++LVG R+Y + ++ +H + + + V+RF+ +S Sbjct: 55 ESLRGALAGCEAVVHLVGIIREYPRQKVTFDRLHRQATAHMLSAAKAQKVQRFVLMSSNG 114 Query: 173 AEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSH 232 AE + S WK + L ++ TI R S +YG+ED F L + +R Sbjct: 115 AEAEGSTAYYR--SKWKAEQLLKASSL-----DWTIFRPSVMYGAEDNFCTLLASMVRI- 166 Query: 233 SNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYK 292 ++P++ +G + PV V DVA IV + D + G + +L+D Sbjct: 167 LPVVPVFGDGCYRI-APVAVQDVAATIVASLARPDACGRSFACCGDQMVTFDELLDIIGG 225 Query: 293 LMRK 296 ++R+ Sbjct: 226 VLRR 229 >UniRef50_O66532 Cluster: NADH dehydrogenase; n=2; Aquifex|Rep: NADH dehydrogenase - Aquifex aeolicus Length = 315 Score = 52.4 bits (120), Expect = 2e-05 Identities = 63/240 (26%), Positives = 109/240 (45%), Gaps = 22/240 (9%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 + G TGFVGR++ +L G ++ R + +RL G+ QV + +++SI Sbjct: 5 ITGATGFVGRHIVRELLNRGYEVHAGVR-NLSKLERL--FGN--QVKGYIVNFDEKDSIR 59 Query: 119 KAVRYSN--VVINLVGRDYETKN--FKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 174 +A+ N VI+L+G YE K + VH + + + + V++F+ +S L Sbjct: 60 EALGKVNPDFVIHLIGILYEEKKKGITFERVHYGHTKNLVEVSKGFNVKKFLFMSALGTH 119 Query: 175 EHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSN 234 + + PS + +K E V TI R S I G E + + K+ + Sbjct: 120 D-------EAPSRYHQTKRWAEREVINSGLNYTIFRPSIILGPEQKLFFDMY-KITKYIP 171 Query: 235 LMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPK----RYLLADLVDWF 290 ++ L G QPV V DVA A ++ +T ++Y+ G K + LLAD+ ++ Sbjct: 172 VVALPDFGNYQF-QPVDVRDVACAYAEALKNPETDRKIYELCGTKVVTFKELLADIFSYW 230 >UniRef50_Q2S702 Cluster: Predicted nucleoside-diphosphate-sugar epimerase; n=1; Hahella chejuensis KCTC 2396|Rep: Predicted nucleoside-diphosphate-sugar epimerase - Hahella chejuensis (strain KCTC 2396) Length = 436 Score = 51.6 bits (118), Expect = 4e-05 Identities = 52/211 (24%), Positives = 89/211 (42%), Gaps = 16/211 (7%) Query: 61 GCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKA 120 G GF+ V KL + G Q++ R + V + + HL E + Sbjct: 7 GAGGFIASVVLEKLLEQGCQVVAVARR----RANIPVSDSVTFIQADLQHLTRMEDWSPM 62 Query: 121 VRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPL 180 +R + VIN G E++ ++ VH + + C + GVERF+ +S L E+ + Sbjct: 63 LRGVDAVINCAGILRESRKGDFDLVHFQAPKALVEACLQNGVERFVQISALGTEQDGGFI 122 Query: 181 VLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRF-LRSLVNKMRSHSNLMPLY 239 K K YL PTA ++R S + + SL+ + + L+ + Sbjct: 123 TSKH----KFDDYL-----MRALPTAVVLRPSVVLSERGSYGGTSLLRALAALPYLLFIP 173 Query: 240 KNGLATVKQPVFVSDVAQGIVNAA-RDDDTK 269 +G + QP+ + D+A + AA R DD + Sbjct: 174 GSGDQKI-QPILLEDLASVVAQAATRTDDAQ 203 >UniRef50_A6TJS1 Cluster: 3-beta hydroxysteroid dehydrogenase/isomerase; n=1; Alkaliphilus metalliredigens QYMF|Rep: 3-beta hydroxysteroid dehydrogenase/isomerase - Alkaliphilus metalliredigens QYMF Length = 286 Score = 50.8 bits (116), Expect = 6e-05 Identities = 61/237 (25%), Positives = 105/237 (44%), Gaps = 27/237 (11%) Query: 61 GCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKA 120 G TGF+G +V ++ K G ++ R + L+ +L V + L D ESI A Sbjct: 6 GATGFLGGFVLEEMVKRGHKVTCFVR----ETSNLEKIKELN-VPYIFGKLDDYESICNA 60 Query: 121 VRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPL 180 ++ +IN+ + H I C+E + R I +S + Sbjct: 61 LKDKETLINIASLGFG---------HAP---HIVNACQEMNINRAIFISTTG-------I 101 Query: 181 VLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGS-EDRFLRSLVNKMRSHSNLMPLY 239 K K + E ++E TIIR + IYG+ +DR + LV ++ S ++P+ Sbjct: 102 FTKLNPDSKGIRLEAERLIKESNLDYTIIRPTMIYGTPKDRNMWRLVQYLKKFS-VLPIL 160 Query: 240 KNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMRK 296 NG ++QPV+V D+A +V+A D + + Y G K ++VD +++ K Sbjct: 161 GNG-TYLQQPVYVKDLAWAVVSAYETDKSIKKAYNISGLKALTYNEVVDVMGRVLGK 216 >UniRef50_Q6L130 Cluster: NADH-dependent oxidoreductase; n=2; Thermoplasmatales|Rep: NADH-dependent oxidoreductase - Picrophilus torridus Length = 280 Score = 49.2 bits (112), Expect = 2e-04 Identities = 51/204 (25%), Positives = 88/204 (43%), Gaps = 25/204 (12%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 V G +GFVGR + L F D + +K + P + E + Sbjct: 5 VMGGSGFVGRNILTGLDADEKAYFSRKNSKFLDEKDIK---------YIPGDIRKPEDVE 55 Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIAR-ICREEGVERFIHLSYLNAEEHP 177 A++ +V+++ + E + K+ DV V+GV+ I I + ++ I+ S +NAE Sbjct: 56 NAIKNYDVIVHAIDVLNENEE-KHEDVAVNGVKNIVNAIKKNSSGQKLIYFSAINAE--- 111 Query: 178 KPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMP 237 K +++ SK L E E + I+R S I+G D F R L++ R + +P Sbjct: 112 -----KGDTSYFRSKRLAEVNA-ELLKNSLIVRPSIIFGPGDAFTRMLISAARMNPPFLP 165 Query: 238 LYKNGLATVKQPVFVSDVAQGIVN 261 N PV++ D+ + N Sbjct: 166 RSGN-----MNPVYIGDLITVLKN 184 >UniRef50_Q7NW82 Cluster: Putative uncharacterized protein; n=1; Chromobacterium violaceum|Rep: Putative uncharacterized protein - Chromobacterium violaceum Length = 277 Score = 48.8 bits (111), Expect = 2e-04 Identities = 48/161 (29%), Positives = 68/161 (42%), Gaps = 12/161 (7%) Query: 125 NVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPLVLKK 184 + V NL G + + + +H G R+A + R GV R++ LS L A H L Sbjct: 52 DAVANLAGAFRQGRAGGFEAIHHAGPLRLAALARAHGVRRWVQLSALGAAAHAGAPFLS- 110 Query: 185 PSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLA 244 SK G+ A+ + A + R S IYG++ R L+ R L+P G Sbjct: 111 ------SKGRGDAALLDCGMEAVVARPSLIYGADGASSRLLLRLARLPFWLLP---EGGG 161 Query: 245 TVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLAD 285 QPV +DVA+G+ D V VG LAD Sbjct: 162 QRIQPVAAADVAEGLQRLIEGDAR--GVIDFVGAAEASLAD 200 >UniRef50_Q5UYL1 Cluster: UDP-glucose 4-epimerase; n=5; Halobacteriaceae|Rep: UDP-glucose 4-epimerase - Haloarcula marismortui (Halobacterium marismortui) Length = 334 Score = 48.8 bits (111), Expect = 2e-04 Identities = 59/234 (25%), Positives = 98/234 (41%), Gaps = 27/234 (11%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLI-LPYRGDFYDAQRLKVCGDLGQVL---------FTP 108 V G GF+G ++ + G ++ L R FYD + D GQ F Sbjct: 11 VTGGAGFIGGHLAQRFAADGHDVVVLDNRDPFYDLDIKQHNVDAGQEAARNSDGSYEFIE 70 Query: 109 YHLLDEESIAKAVRYSNVVINLV---GRDYETKN-FKYNDVHVDGVRRIARICREEGVER 164 + D E + V ++ V + G KN KY++V+V+G + CR+EG+ER Sbjct: 71 GDVRDAELVTDLVADADYVYHQAAQAGVRPSVKNPRKYDEVNVNGTLNLLDACRDEGIER 130 Query: 165 FIHLS---------YLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATI-IRASDI 214 F+ S YL +E + A K++ CA E Y +T+ +R + Sbjct: 131 FVMASSSSVYGKPQYLPYDEQHPTTPVSPYGASKLAAERYACAYSEVYDLSTVALRYFTV 190 Query: 215 YGSEDRFLRSLVNKM-RSHSNLMP-LYKNGLATVKQPVFVSDVAQGIVNAARDD 266 YG R ++ N + R H+ P +Y +G T + ++ DV + +D Sbjct: 191 YGPRMRPNMAISNFVSRCHNGEPPVIYGDGTQT-RDFTYIEDVIDANMTLLHED 243 >UniRef50_A7DQP3 Cluster: 3-beta hydroxysteroid dehydrogenase/isomerase; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: 3-beta hydroxysteroid dehydrogenase/isomerase - Candidatus Nitrosopumilus maritimus SCM1 Length = 289 Score = 48.8 bits (111), Expect = 2e-04 Identities = 36/167 (21%), Positives = 78/167 (46%), Gaps = 10/167 (5%) Query: 113 DEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLN 172 +E+ + ++ S +I+LVG ++ Y ++V ++I + ++ +++ ++ S L Sbjct: 54 EEQLLLPKIKNSYALIHLVGIGKQSTKTDYESINVQLTQKIVNLSKKAKIKKLVYTSGLG 113 Query: 173 AEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSH 232 + + ISK+ E ++ + TI R S I G +D F + L ++ + Sbjct: 114 -------VFADTTMGYFISKFKAETSIIDSKIDYTIFRPSYIVGKDDLFTKYLKKSIKKN 166 Query: 233 SNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPK 279 ++P +G + QP+ + DV + I + D K + VGP+ Sbjct: 167 QIIIP--GSGKYLI-QPISIGDVTKLIFQSIIDKRFKNKTLDLVGPE 210 >UniRef50_A6DZS8 Cluster: NAD-dependent epimerase/dehydratase; n=3; Proteobacteria|Rep: NAD-dependent epimerase/dehydratase - Roseovarius sp. TM1035 Length = 319 Score = 47.6 bits (108), Expect = 6e-04 Identities = 44/152 (28%), Positives = 72/152 (47%), Gaps = 10/152 (6%) Query: 111 LLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSY 170 L D+ ++AK + + V+++ G+ + V+ DGV +A + GV R I +S Sbjct: 52 LSDKAALAKLMAGAQAVVHVAGQVRGRDLADFLGVNADGVTHVAEAAQASGVRRVILISS 111 Query: 171 LNAEE-HPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKM 229 L A H P K + + L + A+ + T+ I+R IYG EDR L L M Sbjct: 112 LAARAPHLSPYAASKRAG---EERLAKVAIGAGF-TSAILRPPAIYGPEDRELVPLFQTM 167 Query: 230 RSHSNLMPLYKNGLATVKQPVF-VSDVAQGIV 260 ++PL G+A + + V D+A+ IV Sbjct: 168 A--RGIVPL--PGVAGARASLLHVDDLARAIV 195 >UniRef50_Q5NR25 Cluster: Predicted nucleoside-diphosphate-sugar epimerase; n=1; Zymomonas mobilis|Rep: Predicted nucleoside-diphosphate-sugar epimerase - Zymomonas mobilis Length = 307 Score = 46.4 bits (105), Expect = 0.001 Identities = 34/110 (30%), Positives = 51/110 (46%), Gaps = 7/110 (6%) Query: 111 LLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSY 170 L DE+S+ K V VI++ G + +++ G ++ + G++RFIH+S Sbjct: 48 LEDEDSLKKLVSSCQAVIHMAGAVKAENREAFAHINLTGTEKLLAATKAAGIKRFIHVSS 107 Query: 171 LNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDR 220 L A E + S + SK E VR TIIR +YGS DR Sbjct: 108 LAARE-------AELSDYGWSKAQSEEKVRSSGLDWTIIRPPAVYGSGDR 150 >UniRef50_A2UCM7 Cluster: NAD-dependent epimerase/dehydratase; n=16; Gammaproteobacteria|Rep: NAD-dependent epimerase/dehydratase - Escherichia coli B Length = 304 Score = 46.0 bits (104), Expect = 0.002 Identities = 49/174 (28%), Positives = 82/174 (47%), Gaps = 18/174 (10%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 V G TGF+G+Y+ + L G + R R V +L V + L D S++ Sbjct: 7 VTGATGFIGKYIIDNLLARGFHVRALTR-----TARAHVNDNLTWVRGS---LEDTHSLS 58 Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEG-VERFIHLSYLNAEEHP 177 + V ++VV++ G+ K + +VDG R+ + +E G +RF+ +S L A HP Sbjct: 59 ELVAGASVVVHCAGQVRGHKEEIFTRCNVDGSLRLMQAAKESGFCQRFLFISSL-AARHP 117 Query: 178 KPLVLKKPSAWKISKYLGE--CAVREEYPTATIIRASDIYGSEDRFLRSLVNKM 229 + S + SKY+ E A + T + R + +YG D+ L+ L + M Sbjct: 118 ------ELSWYAKSKYVAEQRLAAMADEITLGVFRPTAVYGPGDKELKPLFDWM 165 >UniRef50_Q0LK91 Cluster: NAD-dependent epimerase/dehydratase; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: NAD-dependent epimerase/dehydratase - Herpetosiphon aurantiacus ATCC 23779 Length = 286 Score = 45.6 bits (103), Expect = 0.002 Identities = 51/229 (22%), Positives = 101/229 (44%), Gaps = 19/229 (8%) Query: 61 GCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKA 120 G +GF+GR+V +L + G QL R + Q + + L + Sbjct: 7 GASGFIGRHVAEELHQAGHQLTCLVR-----QKPTTPINSATQYVAAEW--LKPTTWLDQ 59 Query: 121 VRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPL 180 + ++VIN VG E++ + VH + + + G+++ I +S L A+ Sbjct: 60 LAEHDMVINCVGMLRESRQASFQAVHTSVPIALFKAAAQYGLQKIIQISALGAD------ 113 Query: 181 VLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYK 240 + P A+ SK L + A+ ++ ++R S +YG+ + L ++ + + P+ Sbjct: 114 -VAAPQAFVRSKALADQALSQQSVPWVVLRPSFVYGA-GCYSMELFRRL-ARLPITPILG 170 Query: 241 NGLATVKQPVFVSDVAQGIVNAARDDD-TKCEVYQAVGPKRYLLADLVD 288 +G V QP+ + D+ + I A D T C + +A G ++ L++ Sbjct: 171 DGSYQV-QPIQIGDLVRAIRQAVEDPTITNC-LIEAGGSEQLSFRQLLE 217 >UniRef50_A1WAD5 Cluster: NAD-dependent epimerase/dehydratase; n=1; Acidovorax sp. JS42|Rep: NAD-dependent epimerase/dehydratase - Acidovorax sp. (strain JS42) Length = 328 Score = 45.6 bits (103), Expect = 0.002 Identities = 47/167 (28%), Positives = 79/167 (47%), Gaps = 14/167 (8%) Query: 56 VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 115 + V G TGF+GR++ L + G ++ L R + A+ + ++ L +E Sbjct: 17 LVAVTGATGFIGRHLIAALVQAGWRVRLLLRREPSGAEWRQSTPEV-----VAGSLDNEA 71 Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVE-RFIHLSYLNAE 174 ++A+ V + VI+L G + + V+ GV RIAR ++ + F+ +S L A Sbjct: 72 AVARLVEGVDAVIHLAGLIKAARRADFFAVNEQGVARIARATKQLSPDAHFLLVSSLAAR 131 Query: 175 EHPKPLVLKKPSAWKISKYLGECAVREEY-PTATIIRASDIYGSEDR 220 E PL+ S + SK GE A + AT++R +YG DR Sbjct: 132 E---PLL----SDYAASKRAGEAAALDAMGARATVLRPPAVYGPGDR 171 >UniRef50_A7H7V8 Cluster: NAD-dependent epimerase/dehydratase; n=2; Deltaproteobacteria|Rep: NAD-dependent epimerase/dehydratase - Anaeromyxobacter sp. Fw109-5 Length = 304 Score = 45.2 bits (102), Expect = 0.003 Identities = 43/152 (28%), Positives = 71/152 (46%), Gaps = 18/152 (11%) Query: 147 VDGVRRIARICREEGVERFIHLSYLN-AEEHPKPLVLKKPSAWKISKYLGECAVREEYPT 205 V+ R + R E GVER +H+S N A + P P K ++ + LGE + + Sbjct: 90 VENSRALFRAAAEAGVERVVHVSITNPAPDSPLPYFRGKA---EVERALGESGL-----S 141 Query: 206 ATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVK-QPVFVSDVAQ-GIVNAA 263 I+R + +G D + ++ +R +PL+ T QPV V D+A+ + +A Sbjct: 142 HAILRPAVFFGGRDVLINNIAWLLRR----LPLFGVASGTYGIQPVHVEDLARLAVEHAE 197 Query: 264 RDDDTKCEVYQAVGPKRYLLADLVDWFYKLMR 295 R D V AVGP+ + +LV + +R Sbjct: 198 RGADV---VLDAVGPEAFAFDELVGLVRRAVR 226 >UniRef50_A7CTR2 Cluster: NAD-dependent epimerase/dehydratase; n=1; Opitutaceae bacterium TAV2|Rep: NAD-dependent epimerase/dehydratase - Opitutaceae bacterium TAV2 Length = 306 Score = 45.2 bits (102), Expect = 0.003 Identities = 45/186 (24%), Positives = 80/186 (43%), Gaps = 12/186 (6%) Query: 102 GQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEG 161 G+V P D +++A+ +V+ N ++ F + V R + R G Sbjct: 49 GRVQAHPLDFRDPDALARHFENVDVLHNTYWVRFDHARFTHEQA-VANTRILFDAARRAG 107 Query: 162 VERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRF 221 V R +H+S N + ++ P + K E A+ E TI+R + ++G Sbjct: 108 VRRIVHVSITNPD-------IQSPLPYFRGKAQVEQALAESGIPHTILRPAVLFGDTAIL 160 Query: 222 LRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRY 281 L ++ +R L ++ +G + QP+ V D+A V+AA D C A GP+ + Sbjct: 161 LNNIAWMLRRFP-LFGVFGDGHYKL-QPIHVEDLADLAVHAAFATDNHC--LDATGPETF 216 Query: 282 LLADLV 287 +LV Sbjct: 217 TYIELV 222 >UniRef50_A1VGT7 Cluster: NAD-dependent epimerase/dehydratase; n=2; Desulfovibrio vulgaris subsp. vulgaris|Rep: NAD-dependent epimerase/dehydratase - Desulfovibrio vulgaris subsp. vulgaris (strain DP4) Length = 304 Score = 45.2 bits (102), Expect = 0.003 Identities = 37/118 (31%), Positives = 61/118 (51%), Gaps = 12/118 (10%) Query: 58 TVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 117 T+FG GF+G +VC+KL + G + + D + L+ Q + T ++LDEE + Sbjct: 4 TLFGGAGFLGSHVCDKLSEAGHDVTVV---DLRPSPYLRP----DQTMITG-NILDEELV 55 Query: 118 AKAVRYSNVVINLVG-RDYETKNFKYND---VHVDGVRRIARICREEGVERFIHLSYL 171 A+AV +++V N G D N + D ++V G CR+ GV+R++ S L Sbjct: 56 ARAVEGADMVFNYAGIADIGEANRRPVDTARINVLGNVIALEACRKAGVKRYVFASSL 113 >UniRef50_A0RYZ0 Cluster: Nucleoside-diphosphate-sugar epimerase; n=1; Cenarchaeum symbiosum|Rep: Nucleoside-diphosphate-sugar epimerase - Cenarchaeum symbiosum Length = 249 Score = 45.2 bits (102), Expect = 0.003 Identities = 37/129 (28%), Positives = 57/129 (44%), Gaps = 10/129 (7%) Query: 151 RRIARICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIR 210 R I ++CR G+ R +LS L A SA +S+Y E + TI R Sbjct: 54 RDIVKLCRTAGIGRITYLSGLGASP-------SSTSAHFLSRYAAEQEIASSGLEYTIFR 106 Query: 211 ASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKC 270 S I G+ DR R L +++ ++P +G V QP+ + D + I ++A D Sbjct: 107 PSFILGTADRLTRGLKKQLKEGGAVIP--GSGEYPV-QPIHIDDACRIIRDSAISDAYLN 163 Query: 271 EVYQAVGPK 279 VGP+ Sbjct: 164 STVDLVGPR 172 >UniRef50_Q89WS9 Cluster: Bll0599 protein; n=1; Bradyrhizobium japonicum|Rep: Bll0599 protein - Bradyrhizobium japonicum Length = 272 Score = 44.4 bits (100), Expect = 0.005 Identities = 61/229 (26%), Positives = 92/229 (40%), Gaps = 21/229 (9%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 V G TG +GR + ++L + G + + R GDL L D +++ Sbjct: 6 VTGGTGHLGRDIVDRLVRSGRHVRVLARSPGTRPDVEWAIGDLATGAGLRDALHDVDTVI 65 Query: 119 KAVRYSNVVINLVGRDYETKNFKY-NDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 177 A YS + G T F + V V+G R+ C E V F+H+S + +E Sbjct: 66 NAATYSPIARR--GGIRPTDFFTSPSAVDVEGTARLLSSCGEARVRHFLHVSIVGLDEAT 123 Query: 178 KPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMP 237 P + K GE VR + +++RA Y DR L L +P Sbjct: 124 LP--------YARVKLAGERLVRASALSWSVVRAMPFYYLLDRLLSGLA--------WLP 167 Query: 238 LYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADL 286 ++ T+ PV SDVA +V A D T+ E + GP+ L L Sbjct: 168 VWPVP-TTLFNPVDTSDVADHVV-ACAFDGTRGERAEIGGPEDIELVSL 214 >UniRef50_Q1YFT6 Cluster: Possible NAD-dependent epimerase/dehydratase; n=1; Aurantimonas sp. SI85-9A1|Rep: Possible NAD-dependent epimerase/dehydratase - Aurantimonas sp. SI85-9A1 Length = 308 Score = 44.0 bits (99), Expect = 0.007 Identities = 61/233 (26%), Positives = 95/233 (40%), Gaps = 29/233 (12%) Query: 61 GCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFT-PYHLLDEESIAK 119 G +GFVGR++ L G +++ RG G G +F P +L D E+ Sbjct: 7 GSSGFVGRHLKAALAADGHDIVVLRRG-----------GPGGDGVFAAPANLADIETTPD 55 Query: 120 AVRYSNVVINLVGRDYETKNFKYND------VHVDGVRRIARICREEGVERFIHLSYLNA 173 R + V +L + D V+ DG +AR +EGV R + +S N Sbjct: 56 WPRGIDAVAHLAAANPGRGTADAADLAALAAVNRDGTAALARRAAQEGVRRMVFVSTANV 115 Query: 174 EE-HPKPLVLKKP----SAWKISKYLGECAVRE----EYPTATIIRASDIYGSEDRFLRS 224 P P+ P SA+ SK+ GE A + T ++R ++G R + Sbjct: 116 HAAFPDPVDEASPIAPQSAYARSKHEGERAFWQGLSGSATTGCVLRPVPVFGPGGRGGIA 175 Query: 225 LVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVG 277 + K+ +PL GLA + V V D+ Q IV A + E++ G Sbjct: 176 ALAKLARMPAPLPL--GGLAAPRSLVAVDDLVQAIVLALTAEQAAGEIFLVAG 226 >UniRef50_A3WA10 Cluster: Predicted nucleoside-diphosphate-sugar epimerase; n=4; Sphingomonadales|Rep: Predicted nucleoside-diphosphate-sugar epimerase - Erythrobacter sp. NAP1 Length = 304 Score = 44.0 bits (99), Expect = 0.007 Identities = 47/205 (22%), Positives = 87/205 (42%), Gaps = 21/205 (10%) Query: 56 VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 115 + + G TGFVG+ + + G + R D +R V + P L E Sbjct: 3 IVAITGATGFVGKATLDVAVQKGLHVRALTRRDAQPRER---------VTWVPGTLDRAE 53 Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 175 ++ + V + VI++ G ++ +V G + + +G+ERF+ +S L+A E Sbjct: 54 ALEELVSGCDAVIHVAGLTSTPNPGRFEAANVTGTANMIAAAKSQGIERFVFVSSLSARE 113 Query: 176 HPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNL 235 SA+ SK E V + TI+R +YG D+ L + + Sbjct: 114 -------PDLSAYGASKAKAERLVEDSGLDWTIVRPPGVYGPGDKDYLDLFKAAK--LGI 164 Query: 236 MPLYKNGLATVKQPVFVSDVAQGIV 260 +P+ G +++ + V D+A+ +V Sbjct: 165 VPVPPEGKSSL---IHVEDLARLLV 186 >UniRef50_A1ASP8 Cluster: NAD-dependent epimerase/dehydratase; n=1; Pelobacter propionicus DSM 2379|Rep: NAD-dependent epimerase/dehydratase - Pelobacter propionicus (strain DSM 2379) Length = 318 Score = 43.6 bits (98), Expect = 0.009 Identities = 54/210 (25%), Positives = 88/210 (41%), Gaps = 18/210 (8%) Query: 54 GIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLD 113 G+ + G TGFVG + +L + ++ R L C + + + L D Sbjct: 13 GLTVALTGGTGFVGGAIIRRLLEDRVRVRALVR-----PASLASCFEAKGLTWIHGELGD 67 Query: 114 EESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREE-GVERFIHLSYLN 172 ES+ + V ++ VI+ G + +V GV RI RE G R + S L Sbjct: 68 RESLRRLVEGASAVIHCAGSVRGACPADFEPANVSGVERIVAAARESAGHPRLLLFSSLA 127 Query: 173 AEEHPKPLVLKKPSAWKISKYLGECAVREEYPTA--TIIRASDIYGSEDRFLRSLVNKMR 230 A + S + SK GE A+R TI+R +YG DR + L+ MR Sbjct: 128 ARS-------PELSDYAASKRRGEDALRSAAQGLDWTILRPPAVYGPGDREMLPLLQWMR 180 Query: 231 SHSNLMPLYKNGLATVKQPVFVSDVAQGIV 260 +P G ++ ++VSD+A+ ++ Sbjct: 181 RGILFVPGSGAGRLSL---IYVSDLAEAVL 207 >UniRef50_A3YG10 Cluster: Putative uncharacterized protein; n=1; Marinomonas sp. MED121|Rep: Putative uncharacterized protein - Marinomonas sp. MED121 Length = 306 Score = 43.2 bits (97), Expect = 0.012 Identities = 39/145 (26%), Positives = 64/145 (44%), Gaps = 11/145 (7%) Query: 61 GCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCG-DLGQVLFTPYHLLDEESIAK 119 G TG++GRY+ +L K I R ++L+ G + Q+ + D S+A Sbjct: 9 GATGYLGRYLVQRLLKQNGPFIAMGRS----IKKLESMGLETQQIRLA--QVTDPISLAG 62 Query: 120 AVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP-- 177 +VVI+ VG + Y DV + GV++FI++S NA H Sbjct: 63 CCHGIDVVISCVGITRQKDGLNYMDVDYQANINLLEEAERSGVKKFIYISAFNAPNHQSV 122 Query: 178 KPLVLKKPSAWKI--SKYLGECAVR 200 + L K+ A ++ S+ L C +R Sbjct: 123 RMLYAKEQFAQRLLSSQMLAPCVIR 147 >UniRef50_Q8KDL0 Cluster: 3-beta hydroxysteroid dehydrogenase/isomerase family protein; n=10; Chlorobiaceae|Rep: 3-beta hydroxysteroid dehydrogenase/isomerase family protein - Chlorobium tepidum Length = 331 Score = 42.3 bits (95), Expect = 0.022 Identities = 31/117 (26%), Positives = 54/117 (46%), Gaps = 5/117 (4%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 V G TGF+G + ++L G + + R D LK C L ++ + D S++ Sbjct: 7 VTGGTGFIGSRLVHRLAASGEDVYVLVRASS-DLASLKEC--LDRITLVYGDVTDIASLS 63 Query: 119 KAVRYSNVVINLVGRDY--ETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA 173 A + V + G Y + KN ++V+G + + CR V+R +H+S + A Sbjct: 64 GAFEGAEEVYHCAGITYMGDRKNPLLQRINVEGTQNVLDACRRAKVKRVVHVSSITA 120 >UniRef50_A2C1Q9 Cluster: Putative uncharacterized protein; n=1; Prochlorococcus marinus str. NATL1A|Rep: Putative uncharacterized protein - Prochlorococcus marinus (strain NATL1A) Length = 299 Score = 42.3 bits (95), Expect = 0.022 Identities = 29/91 (31%), Positives = 47/91 (51%), Gaps = 3/91 (3%) Query: 207 TIIRASDIYGS-EDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARD 265 TIIR + IYGS +DR + L+ K + ++P++ NG +++QPV V DVA +V Sbjct: 136 TIIRPTMIYGSPKDRNMIKLI-KWIDNMPIIPIFGNG-KSLQQPVNVKDVAWSLVKIIDK 193 Query: 266 DDTKCEVYQAVGPKRYLLADLVDWFYKLMRK 296 T + G + +VD K++ K Sbjct: 194 KSTYYRSFNISGKEPLTFTQIVDIIEKMLNK 224 >UniRef50_Q2W798 Cluster: DTDP-6-deoxy-L-mannose-dehydrogenase; n=2; Magnetospirillum|Rep: DTDP-6-deoxy-L-mannose-dehydrogenase - Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) Length = 296 Score = 41.5 bits (93), Expect = 0.038 Identities = 34/103 (33%), Positives = 50/103 (48%), Gaps = 8/103 (7%) Query: 136 ETKNFKYNDVHVDGVRRIARICREEGVERFIHLS--YLNAEEHPKPLVLKKP----SAWK 189 ET+ ++ +G +AR C G+ IHLS Y+ P+P P S + Sbjct: 68 ETETAAAMAINGEGPAHLARACAARGIP-LIHLSTDYVFDGRSPEPYREDAPMAPLSVYG 126 Query: 190 ISKYLGECAVREEYPTATIIRASDIYGSE-DRFLRSLVNKMRS 231 SK GE AVR P I+R S +YG E F+R++V +R+ Sbjct: 127 ASKAAGEEAVRWLQPDHAILRVSWLYGGERGDFVRAMVGAIRA 169 >UniRef50_Q2RKH0 Cluster: NAD-dependent epimerase/dehydratase; n=2; Firmicutes|Rep: NAD-dependent epimerase/dehydratase - Moorella thermoacetica (strain ATCC 39073) Length = 323 Score = 41.5 bits (93), Expect = 0.038 Identities = 65/258 (25%), Positives = 111/258 (43%), Gaps = 28/258 (10%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQL--ILPY--RGDFYDAQRLKVCGDLGQVLFTPYHLLDE 114 V G GF+G ++ KL + G ++ + Y R + + +V D+ +FT + D Sbjct: 5 VTGAGGFIGSHLTEKLVREGHKVRAFVHYNSRNTWGWLEESEVKDDIE--VFTG-DIRDY 61 Query: 115 ESIAKAVRYSNVVINL---VGRDYE-TKNFKYNDVHVDGVRRIARICREEGVERFIHLS- 169 +S+ ++R VV +L +G Y Y +V+G I + REEG+ R +H S Sbjct: 62 DSVRASLRGIEVVFHLAALIGIPYSYVTPVAYIKTNVEGTYNICQAAREEGLRRVVHTST 121 Query: 170 --------YLNAEEHPKPLVLKKP-SAWKI-SKYLGECAVREEYPTATIIRASDIYG--- 216 Y+ +E+ PL + P +A KI + L R TIIR + YG Sbjct: 122 SEVYGTARYVPIDEN-HPLQAQSPYAASKIGADQLALSFYRSFDLPVTIIRPFNTYGPRQ 180 Query: 217 SEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAV 276 S + +++ ++ S + L LA + FV D G + A T EV Sbjct: 181 SARAVIPTIITQLLSGREEIRL--GNLAPTRDFNFVEDTVNGFITAGLSPHTVGEVVNIG 238 Query: 277 GPKRYLLADLVDWFYKLM 294 + + +LV+ +L+ Sbjct: 239 SGREISIGELVELIGQLI 256 >UniRef50_Q1LGK6 Cluster: NAD-dependent epimerase/dehydratase; n=1; Ralstonia metallidurans CH34|Rep: NAD-dependent epimerase/dehydratase - Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839) Length = 430 Score = 41.5 bits (93), Expect = 0.038 Identities = 58/237 (24%), Positives = 96/237 (40%), Gaps = 21/237 (8%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 V G +G +G +C +L G ++I RG V D G T + E Sbjct: 11 VCGASGLIGAVLCKRLEAQGHEVI---RGVRTPTSARDVAMDFG----TDTTI---EQWL 60 Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 178 V+ +VVIN VG ET ++ VH + R C + GV R I +S L A+ Sbjct: 61 PRVQGMHVVINAVGIIVETGTNRFEAVHHLAPAALFRACAKAGVGRVIQISALGADRGDT 120 Query: 179 PLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPL 238 P K A + + L V+ + +++ A D G R+L + ++P+ Sbjct: 121 PYFRSKRGADDVLRAL---PVQWQVLYPSLVYAQD--GDSAAMFRTLAS-----LPVIPV 170 Query: 239 YKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMR 295 + G A QPV + D+ +V + + VG R ++D + + M+ Sbjct: 171 PELGDARF-QPVHIDDLVDTVVTVIVPAIPPGQCIEVVGASRMSYRAMLDTYRQGMQ 226 >UniRef50_A7BY73 Cluster: NAD-dependent epimerase/dehydratase; n=1; Beggiatoa sp. PS|Rep: NAD-dependent epimerase/dehydratase - Beggiatoa sp. PS Length = 308 Score = 41.5 bits (93), Expect = 0.038 Identities = 51/229 (22%), Positives = 102/229 (44%), Gaps = 17/229 (7%) Query: 61 GCTGFVGRYVCNKLGKIGTQLILPYRG-DFYDAQRLKVCGDLGQVLFTPYHLLDEESI-A 118 G +GF+G+++ + L G Q++ R + + A+ +V + L Y E I Sbjct: 7 GASGFIGQHLLSALMAKGYQIVACVRQPNQWQARFPEV-----KWLACDYAKDHEPHIWL 61 Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 178 + +VVIN VG ET+ ++ D+H + + + G+ + + +S L A+E Sbjct: 62 PRLEQIDVVINAVGIIRETRGQRFEDLHTHAPIALFKAAEQLGIRKILQISALGADE--- 118 Query: 179 PLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPL 238 K SA+ +SK + A+ A II+ S + G S + + ++P+ Sbjct: 119 ----KAESAYHLSKRAADEALLTLTVDAMIIQPSIVIGRGGG--SSTLFSAMAALPVIPV 172 Query: 239 YKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287 +G + QP+ + D+ ++ R+ + + + VG +R L+ Sbjct: 173 IGSGEQPI-QPIAIEDLTACVLALLRNWPSSNQRIELVGAQRMTFLQLL 220 >UniRef50_Q12VM5 Cluster: NAD-dependent epimerase/dehydratase; n=2; cellular organisms|Rep: NAD-dependent epimerase/dehydratase - Methanococcoides burtonii (strain DSM 6242) Length = 294 Score = 41.5 bits (93), Expect = 0.038 Identities = 60/242 (24%), Positives = 105/242 (43%), Gaps = 31/242 (12%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 VFG GF+G Y+ +L + Y D K + + +F ++LD+ +A Sbjct: 7 VFGGCGFLGSYLVERL------CMKKYEVTVADLNLSKY---INKDIFVECNILDKIKVA 57 Query: 119 KAVRYSNVVINLVGRDYETKNFKYN----DVHVDGVRRIARICREEGVERFIHLSYLNAE 174 + V+ +++V N G K + +++V G I C + GVERF++ S + Sbjct: 58 ELVKNADIVYNFAGMANLDKAVEDPCGTIELNVIGNLNILDACMQSGVERFVYASSAYS- 116 Query: 175 EHPKPLVLKKPSAWKISKYLGECAVREEYPTA-----TIIRASDIYG---SEDRFLRSLV 226 + K S + ISK E + EEY TIIR +Y SE+ ++ +L+ Sbjct: 117 ------MSDKGSFYGISKLTSEKLI-EEYNAKYDLKYTIIRYGSVYSERISENNYIYNLL 169 Query: 227 NKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADL 286 K S + + +G +++ + SDVAQ V + + E G +R +L Sbjct: 170 -KNAIISGKIKHFGDG-EEIREYIHASDVAQLSVEIIESNQFENEHIILTGMERMKRKEL 227 Query: 287 VD 288 + Sbjct: 228 FE 229 >UniRef50_Q0C1U1 Cluster: Putative UDP-glucose 4-epimerase; n=1; Hyphomonas neptunium ATCC 15444|Rep: Putative UDP-glucose 4-epimerase - Hyphomonas neptunium (strain ATCC 15444) Length = 330 Score = 41.1 bits (92), Expect = 0.050 Identities = 46/171 (26%), Positives = 75/171 (43%), Gaps = 14/171 (8%) Query: 61 GCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKA 120 G TGFVGR +L + TQ +P R Q + D + + L + +++ Sbjct: 11 GATGFVGR----QLLRDRTQNSVPVRA-LARMQPHRKLTDGNGIEWISGDLSSDAALSSL 65 Query: 121 VRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPL 180 V +++VI+L G + +V+ + R + GV+ F+H+S L A +P Sbjct: 66 VSNADIVIHLAGATKARNASVFREVNALRTAELVRRAQAAGVQHFVHVSSLTAS---RPD 122 Query: 181 VLKKPSAWKISKYLGECAVREEYPT--ATIIRASDIYGSEDRFLRSLVNKM 229 + SA+ SK E E + TI+RA I G D RSL + + Sbjct: 123 I----SAYAKSKAESEILAAENAGSMALTIVRAPAILGPGDDATRSLFSAL 169 >UniRef50_Q0ANG5 Cluster: NAD-dependent epimerase/dehydratase precursor; n=1; Maricaulis maris MCS10|Rep: NAD-dependent epimerase/dehydratase precursor - Maricaulis maris (strain MCS10) Length = 431 Score = 41.1 bits (92), Expect = 0.050 Identities = 39/163 (23%), Positives = 64/163 (39%), Gaps = 9/163 (5%) Query: 125 NVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPLVLKK 184 +VVIN VG + VHVDG + + C + GV R +H+S + + Sbjct: 67 DVVINCVGVLQDGLGDSSRKVHVDGAMALFKACEQAGVGRVLHISAVGVD-------TAA 119 Query: 185 PSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLA 244 S + K GE A+ I+R S + +LV + + P+ G Sbjct: 120 GSDYARDKLAGEAALAARDLDWLILRPSLVVARNVYGGTALVRSLCGIPFVTPVV--GGE 177 Query: 245 TVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287 V +P+ + D+ + + + GP+R LAD V Sbjct: 178 QVFRPIGMDDLCEAVAGLIEPGAPARTSFDLAGPERVSLADTV 220 >UniRef50_A3ZLP8 Cluster: NAD-dependent epimerase/dehydratase family protein/3- betahydroxysteroid dehydrogenase/isomerase family protein; n=1; Blastopirellula marina DSM 3645|Rep: NAD-dependent epimerase/dehydratase family protein/3- betahydroxysteroid dehydrogenase/isomerase family protein - Blastopirellula marina DSM 3645 Length = 339 Score = 41.1 bits (92), Expect = 0.050 Identities = 50/173 (28%), Positives = 72/173 (41%), Gaps = 17/173 (9%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 V G TGF+GRY+C +L G L R + LG V L + + Sbjct: 6 VTGATGFIGRYLCRRLVADGHSLRCAVR----QTSATEPLEQLG-VELVEVDLSNPHDLE 60 Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIAR-ICREEGVERFIHLSYLNA---- 173 +A+ + ++ G T K V+ DG RRI + +++S L A Sbjct: 61 QAIEGCEAIFHVAGLICATAPEKLFHVNRDGTRRIVEAAAAQTNPPTVLYISSLAAVGPS 120 Query: 174 -EEHPK-PLVLKKP-SAWKISKYLGEC---AVREEYPTATIIRASDIYGSEDR 220 EH K P KP S + SK GE V + P TI+R S ++G E+R Sbjct: 121 RTEHKKRPDHFPKPVSNYGRSKRAGERQAELVADRVP-ITIVRPSIVFGGENR 172 >UniRef50_A0NYC5 Cluster: DTDP-glucose 4,6-dehydratase; n=1; Stappia aggregata IAM 12614|Rep: DTDP-glucose 4,6-dehydratase - Stappia aggregata IAM 12614 Length = 348 Score = 40.7 bits (91), Expect = 0.066 Identities = 34/126 (26%), Positives = 56/126 (44%), Gaps = 9/126 (7%) Query: 51 SFNGIVATVFGCTGFVGRYVCNKLGK---IGTQLILPYRGDFYDAQRLKVCGDLGQVLFT 107 SF IV T G GF+G V ++ + + +IL D +RL GD G + Sbjct: 29 SFRKIVVT--GGLGFIGSKVFKRVARMANVAETVILDRVSYAADFRRLAPVGDAGDLPVI 86 Query: 108 PYHLLDEESIAKAVRYSNVVINLVGRDYETKNFK----YNDVHVDGVRRIARICREEGVE 163 + +A A+ + VI+L + ++F + DV+V G + + GV+ Sbjct: 87 RGDIRSPIDVAAALHDCDAVIHLAAETHVPRSFTAPELFFDVNVTGTEVLLNAALDAGVK 146 Query: 164 RFIHLS 169 FIH+S Sbjct: 147 HFIHIS 152 >UniRef50_Q0S7J3 Cluster: Reductase; n=2; Nocardiaceae|Rep: Reductase - Rhodococcus sp. (strain RHA1) Length = 336 Score = 39.9 bits (89), Expect = 0.12 Identities = 61/227 (26%), Positives = 94/227 (41%), Gaps = 29/227 (12%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 V G GFVG + N L + G ++ D R + + G V + +LD ES+ Sbjct: 5 VTGAAGFVGNNLLNLLVEAGHEVTA------IDRVRSRYAPEYG-VTWVNADVLDVESMK 57 Query: 119 KAVRYSNVVINLVGR-DYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA---- 173 +A+ + VV +LV K+ V+ GVR +A GV R +H S +++ Sbjct: 58 RALEGAEVVYHLVAMITLAQKDDLAWTVNTKGVRTVAEAALAVGVRRMVHCSSVHSFDQS 117 Query: 174 -------EEHPKPLVLKKPSAWKISKYLGECAVREEYPT---ATIIRASDIYGSEDRFLR 223 E P+ + P + SK+ GE +RE A I + +YG D L Sbjct: 118 SCGGTLDENSPRSVDASIP-VYDRSKWAGEIELREVVEAGLDAVICNPTGVYGPVDYGL- 175 Query: 224 SLVNKMRSHS--NLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDT 268 S VN + ++ +P G V V DVA G++ A T Sbjct: 176 SRVNALLRNAARGRVPAAVQGGFDF---VDVRDVAAGLIAAGEKGRT 219 >UniRef50_Q0DWQ7 Cluster: Cyclin-B1-2; n=6; Oryza sativa|Rep: Cyclin-B1-2 - Oryza sativa subsp. japonica (Rice) Length = 391 Score = 39.9 bits (89), Expect = 0.12 Identities = 23/58 (39%), Positives = 33/58 (56%), Gaps = 4/58 (6%) Query: 248 QPVFVSDVAQGIVNAARDDDTKC-EVYQAVGPKRYLLADLVDWFYKLMRKDEKWGGYI 304 QPV+V DVA IVN+ +DD T + Y GP+ Y + DL + Y+ + +W YI Sbjct: 322 QPVYVVDVAAAIVNSLKDDGTSMGKSYGLGGPEIYTVHDLAELMYETIC---EWPRYI 376 >UniRef50_Q5ZVY7 Cluster: Oxidoreductase; n=4; Legionella pneumophila|Rep: Oxidoreductase - Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 /ATCC 33152 / DSM 7513) Length = 432 Score = 39.5 bits (88), Expect = 0.15 Identities = 54/230 (23%), Positives = 94/230 (40%), Gaps = 14/230 (6%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPY-HLLDEESI 117 V G +GF+ L G ++I R + QR+ G QV+F + + E Sbjct: 5 VTGASGFIASQFVTDLLIAGHEIICCVRNTKH-TQRI-FPG--AQVIFCDFINDTKPEIW 60 Query: 118 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 177 +K ++ +VVIN VG Y +VH + + + C GV++ I +S L ++ Sbjct: 61 SKRLQGIDVVINCVGILYHPDERIIWNVHYETPKALFDACINSGVKKIIQISALGIDKVD 120 Query: 178 KPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMP 237 K + I YL ++ + I+R S +YG SL + Sbjct: 121 VSYATSKKA---IDDYLLTLSI-----PSVIVRPSYVYGKGSYGGSSLFRGIAGTPFFTA 172 Query: 238 LYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287 + G QP+ ++D++Q IV T+ + AV K L +++ Sbjct: 173 IPGQGTQKF-QPISLNDLSQAIVRLVSTPVTETIILHAVSKKIITLEEII 221 >UniRef50_A0A018 Cluster: MoeS5; n=4; Actinomycetales|Rep: MoeS5 - Streptomyces ghanaensis Length = 282 Score = 39.5 bits (88), Expect = 0.15 Identities = 38/139 (27%), Positives = 58/139 (41%), Gaps = 11/139 (7%) Query: 145 VHVDGVRRIARICREEGVERFIHLS----YLNAEEHPKPLVLKKP-SAWKISKYLGECAV 199 V DG R+A G R +H+S + A+ H L P S + +K E AV Sbjct: 78 VTADGAARLALEAARAGC-RLVHVSSDAVFSGADVHYPEEALPDPVSPYGAAKAAAETAV 136 Query: 200 REEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGI 259 R P A ++R S I G V+ + + L+ + V+ PV V D+A + Sbjct: 137 RVAVPEAAVVRTSLIVGHNRSAHEEAVHALAAGRRAGVLFTD---DVRCPVHVDDLASAL 193 Query: 260 VNAARDDDTKCEVYQAVGP 278 + A D + V+ GP Sbjct: 194 LEIAASDGS--GVFHVAGP 210 >UniRef50_Q5V0D3 Cluster: DTDP-glucose-46-dehydratase; n=2; Halobacteriaceae|Rep: DTDP-glucose-46-dehydratase - Haloarcula marismortui (Halobacterium marismortui) Length = 294 Score = 39.5 bits (88), Expect = 0.15 Identities = 57/223 (25%), Positives = 92/223 (41%), Gaps = 25/223 (11%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVC---GDLGQVLFTPYHLLDEE 115 V G TGF+GR + L G ++ R ++ V GDLG+ L D+ Sbjct: 5 VMGATGFIGRRLVRALDDAGHDVVAFSRSASEESFPEGVEPFEGDLGEPDSLD-GLCDDI 63 Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 175 +A + +S L ++ + +Y RR A GV+R ++LS ++ +E Sbjct: 64 DVAYYLIHS-----LTSENFAELDRRY-------ARRFADSASAAGVDRVVYLSGISGDE 111 Query: 176 HPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNL 235 + S S+ E + E T++RA+ I G E R +V+ + L Sbjct: 112 -------ENLSPHLASRREVESVLAEGSFDLTVLRAAVIIGPESASFR-IVDDLTDRLPL 163 Query: 236 MPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGP 278 M L + T QP+ V D +V D+T+ E Y GP Sbjct: 164 M-LVPKWVRTPCQPIGVDDAISYLVELLDADETRGETYDIGGP 205 >UniRef50_Q2W604 Cluster: Predicted nucleoside-diphosphate-sugar epimerase; n=1; Magnetospirillum magneticum AMB-1|Rep: Predicted nucleoside-diphosphate-sugar epimerase - Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) Length = 343 Score = 39.1 bits (87), Expect = 0.20 Identities = 22/63 (34%), Positives = 28/63 (44%) Query: 114 EESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA 173 E +A + +VV+N G + VH G R+ R C GV R IHLS L A Sbjct: 43 EAVLAAHLTGHDVVVNAAGLVRGRGSNTMAAVHAQGTERLVRACLAAGVSRLIHLSALGA 102 Query: 174 EEH 176 H Sbjct: 103 SSH 105 >UniRef50_A1VMB7 Cluster: NAD-dependent epimerase/dehydratase; n=3; Comamonadaceae|Rep: NAD-dependent epimerase/dehydratase - Polaromonas naphthalenivorans (strain CJ2) Length = 305 Score = 39.1 bits (87), Expect = 0.20 Identities = 35/161 (21%), Positives = 62/161 (38%), Gaps = 6/161 (3%) Query: 127 VINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPLVLKKPS 186 V+N VG + + +H D + + C +GV R IHLS L P K + Sbjct: 75 VVNAVGVLRDGPHTPMQAIHTDVPKALFNACARQGVRRVIHLSALGIASSPSRYATAKRA 134 Query: 187 AWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATV 246 A +L + ++ ++ S ++G R L+P + + Sbjct: 135 A---EAHL-QALTQQGALQGVALQPSIVFGPGGAGCELFTALARWPVMLLP--RQAFSAR 188 Query: 247 KQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287 QPV++ ++A+ + A C VGP+ LA + Sbjct: 189 VQPVWIRELAEVVATLAGPAAELCGTLPCVGPEGTPLASFI 229 >UniRef50_Q73MR8 Cluster: Epimerase/dehydratase, putative; n=2; Bacteria|Rep: Epimerase/dehydratase, putative - Treponema denticola Length = 329 Score = 38.7 bits (86), Expect = 0.27 Identities = 45/162 (27%), Positives = 76/162 (46%), Gaps = 25/162 (15%) Query: 113 DEESIAKAVRYS-NVVINLVGR---DYETKNFKYNDVHVDGVRRIARICREEGVERFIHL 168 D +S+ K + S + VINL D E K+ Y++V+VDG + ++C E G+++ I Sbjct: 49 DIDSLKKELSSSLDCVINLAAEHRDDVEPKSL-YDEVNVDGAENVCKVCSELGIKKIIFT 107 Query: 169 SY--------LNAEEHPKPLVLKKPSAWKISKYLGECAVR-----EEYPTATIIRASDIY 215 S LN E K + + + +K+L E R + + TIIR + ++ Sbjct: 108 SSVAVYGFAPLNTNETGK---INYFNDYGRTKWLAEGKYRAWIENDNENSLTIIRPTVVF 164 Query: 216 GSEDRFLRSLVNKMRS-HSNLMPLYKNGLATVKQPVFVSDVA 256 G ++R ++ N +R S P NG K +V +VA Sbjct: 165 GEQNR--GNVYNLLRQISSGFFPFVGNG-KNKKSMAYVENVA 203 >UniRef50_Q11Z70 Cluster: Nucleoside-diphosphate-sugar epimerase; n=1; Cytophaga hutchinsonii ATCC 33406|Rep: Nucleoside-diphosphate-sugar epimerase - Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469) Length = 322 Score = 38.7 bits (86), Expect = 0.27 Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 5/117 (4%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 V G G VG ++CN+L G ++ R + D LK G + + D S+ Sbjct: 4 VTGANGLVGSFLCNELAGKGYRVKALVR-EKSDTSLLKAVA--GSIELVYGDITDAGSLV 60 Query: 119 KAVRYSNVVINLVG--RDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA 173 A+ V++ + KN + +V G R + + E+GV++ IH+S + A Sbjct: 61 DAMEDVMCVVHTAAVISFWNKKNKEMYQTNVVGTRNVVDVALEKGVKKMIHISSIAA 117 >UniRef50_A7FIK2 Cluster: NAD-dependent epimerase/dehydratase family protein; n=11; Enterobacteriaceae|Rep: NAD-dependent epimerase/dehydratase family protein - Yersinia pseudotuberculosis IP 31758 Length = 338 Score = 38.7 bits (86), Expect = 0.27 Identities = 40/162 (24%), Positives = 72/162 (44%), Gaps = 16/162 (9%) Query: 142 YNDVHVDGVRRIARICREEGVERFIHLS----YLNAEEH---PKPLVLKK-PSAWKISKY 193 ++ +V ++A+ EGV+RFIH+S Y + H P+ + S + SKY Sbjct: 86 FHQTNVVVTHKLAQAAGREGVKRFIHISSPAVYFDFRHHHDLPETYRASRFSSHYASSKY 145 Query: 194 LGECAVRE---EYPTAT--IIRASDIYGSEDR-FLRSLVNKMRSHSNLMPLYKNGLATVK 247 E + E YP T I+R ++G DR + L+ ++ N++ L G A + Sbjct: 146 AAEQVLHECIAHYPDTTYVILRPRGLFGPHDRVIVPRLLQQLSRDRNVLRLPGGGQAQL- 204 Query: 248 QPVFVSDVAQGIVNAARDDDTKC-EVYQAVGPKRYLLADLVD 288 FV +V ++ A +D + +Y + L ++D Sbjct: 205 DLTFVLNVVHAMMLATDNDGLRSGAIYNITNQEPQRLVTMLD 246 >UniRef50_A4BUQ8 Cluster: DTDP-4-dehydrorhamnose reductase; n=3; Proteobacteria|Rep: DTDP-4-dehydrorhamnose reductase - Nitrococcus mobilis Nb-231 Length = 291 Score = 38.7 bits (86), Expect = 0.27 Identities = 33/107 (30%), Positives = 52/107 (48%), Gaps = 8/107 (7%) Query: 136 ETKNFKYNDVHVDGVRRIARICREEGVERFIHLS----YLNAEEHP-KPLVLKKP-SAWK 189 ET+ V+V G +AR RE G R +H+S + A+ P P P + + Sbjct: 66 ETERAAAYAVNVGGAEHMARAARELGC-RLVHISTDFVFDGAQGRPYTPESKPNPLNVYG 124 Query: 190 ISKYLGECAVREEYPTATIIRASDIYG-SEDRFLRSLVNKMRSHSNL 235 SK GE A + P A I+R + +YG + F+ S++ MR+ + L Sbjct: 125 ASKLAGEQAAQAIKPDALILRTAWLYGETGSNFVHSMLRLMRTRAEL 171 >UniRef50_A3CRA1 Cluster: DTDP-4-dehydrorhamnose 3,5-epimerase, putative; n=4; Bacteria|Rep: DTDP-4-dehydrorhamnose 3,5-epimerase, putative - Streptococcus sanguinis (strain SK36) Length = 343 Score = 38.3 bits (85), Expect = 0.35 Identities = 56/242 (23%), Positives = 105/242 (43%), Gaps = 20/242 (8%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 V G TGF+G+YV +L + G Q + + + ++L+ G L V F EE I Sbjct: 23 VTGATGFLGKYVVEELAEQGYQ-VRAFGRNLKAGRQLE--GPL--VEFFAGDFTREEEIF 77 Query: 119 KAVRYSNVVINLVGRDYETKNF-KYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 177 A + V++ + ++ +V G + + CR GV+R +++S + Sbjct: 78 AACEGVDAVVHAGALSTIWGPWEQFYQTNVVGTKLVMEACRHFGVQRLVYISSPSVYAAA 137 Query: 178 K-PLVLKKPSA--------WKISKYLGECAVREEYP--TATIIRASDIYGSEDRFLRSLV 226 + L +K+ +A + SK + E VR YP + I+R ++G D + + Sbjct: 138 RDQLDIKEEAAPQENELNFYIKSKLMAERIVR-SYPQVPSVILRPRGLFGIGDTSIFPRI 196 Query: 227 NKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADL 286 ++ S +PL +NG + V +VA + A + + +VY + D+ Sbjct: 197 LRL-SQKLAIPLIRNG-QQMMDMTCVENVALAVRLALEIPEAQGQVYNITNGESRSFKDM 254 Query: 287 VD 288 +D Sbjct: 255 LD 256 >UniRef50_Q9A4D7 Cluster: Putative uncharacterized protein; n=1; Caulobacter vibrioides|Rep: Putative uncharacterized protein - Caulobacter crescentus (Caulobacter vibrioides) Length = 430 Score = 37.9 bits (84), Expect = 0.46 Identities = 42/163 (25%), Positives = 66/163 (40%), Gaps = 13/163 (7%) Query: 127 VINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPLVLKKPS 186 V+N G ++ N VHV+GVRR+A+ C E R +H+S E KP+ Sbjct: 69 VVNCAGALQDSPRDDLNAVHVEGVRRLAQAC-EAKRARLVHISAAGVE-------ADKPT 120 Query: 187 AWKISKYLGECAVREEYPTA--TIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLA 244 A+ +K+ E A+ P ++R + G +L+ + P+ +G + Sbjct: 121 AFNTTKHEAE-ALLAAMPALDWVVLRPGLVIGPAAYGGTALLRGLAGFPGFSPVV-HGQS 178 Query: 245 TVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287 V Q V DVA + D V + L DLV Sbjct: 179 RV-QVVATDDVAAAVARCLAPDAPLRRRLDLVHAEAVTLTDLV 220 >UniRef50_Q82X00 Cluster: Putative UDP-glucose 4-epimerase; n=1; Nitrosomonas europaea|Rep: Putative UDP-glucose 4-epimerase - Nitrosomonas europaea Length = 315 Score = 37.9 bits (84), Expect = 0.46 Identities = 41/149 (27%), Positives = 69/149 (46%), Gaps = 12/149 (8%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 V G GFVG+ +C L + G + + R + + V G+ T + + +E I Sbjct: 5 VTGANGFVGQTLCPALERAGLRAVRAVRISTR-YEEISVGEVDGE---TSWSRVFDEGID 60 Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLN--AEEH 176 V + + L ++ E + Y+ V+ G R+AR C G+ RF+ +S + EE Sbjct: 61 GVVHLA-AKVPLAEKEKEAAD-SYHRVNTLGTVRLARECAARGIRRFVFISTVKVLGEEC 118 Query: 177 PKPLVLKK---PS-AWKISKYLGECAVRE 201 KP PS A+ ISK+ E ++R+ Sbjct: 119 DKPFQADDSAVPSDAYAISKWEAEQSLRQ 147 >UniRef50_Q2Y734 Cluster: NAD-dependent epimerase/dehydratase precursor; n=1; Nitrosospira multiformis ATCC 25196|Rep: NAD-dependent epimerase/dehydratase precursor - Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849) Length = 439 Score = 37.9 bits (84), Expect = 0.46 Identities = 54/242 (22%), Positives = 97/242 (40%), Gaps = 17/242 (7%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYR-GDFYDAQRLKVCGDLGQVLFTPYHL--LDEE 115 + G +GF+G ++ L G +++ R G D + +K G D E Sbjct: 6 ITGASGFIGSHLVMALAAAGHRIVCATRRGQPEDIRGIKDLKGTGPTYIAADFTRDFDME 65 Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 175 K + +VVIN VG E + +H R + C V + + +S L A+E Sbjct: 66 VWKKRLAGIDVVINAVGILREHGRQTFQALHDRAPRALFAACEAANV-KVVQISALGADE 124 Query: 176 HPKPLVLKKPSAWKISKYLGECAVR---EEYPTATIIRASDIYGSEDRFLRSLVNKMRSH 232 + + S + +SK + A+ + +++ S +YG + L N + S Sbjct: 125 NAR-------SRYHLSKKAADDALLASPNNRSKSMVVQPSLVYGPGGTSAQ-LFNLIASL 176 Query: 233 SNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYK 292 ++PL G + QP+ + D+ Q +V + D + VGP+ D + Sbjct: 177 P-VIPLPGAGNQRI-QPIHIDDLTQAVVELLQTDRYLGQRIPLVGPEPITFRDYLGELRH 234 Query: 293 LM 294 LM Sbjct: 235 LM 236 >UniRef50_Q2S3D1 Cluster: NAD-dependent epimerase/dehydratase family protein/3-beta hydroxysteroid dehydrogenase/isomerase family protein; n=1; Salinibacter ruber DSM 13855|Rep: NAD-dependent epimerase/dehydratase family protein/3-beta hydroxysteroid dehydrogenase/isomerase family protein - Salinibacter ruber (strain DSM 13855) Length = 339 Score = 37.9 bits (84), Expect = 0.46 Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 2/67 (2%) Query: 207 TIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDD 266 T++R +YG DR + ++ H + P+ G A V V D+A G+V+AAR Sbjct: 171 TVVRPPAVYGPRDRDILDFFRAVKRH--VCPIVGGGSARTLSLVHVRDLATGMVDAARHP 228 Query: 267 DTKCEVY 273 E Y Sbjct: 229 GAHGETY 235 >UniRef50_Q9X9X6 Cluster: Putative uncharacterized protein SCO1896; n=2; Streptomyces|Rep: Putative uncharacterized protein SCO1896 - Streptomyces coelicolor Length = 269 Score = 37.5 bits (83), Expect = 0.61 Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 1/106 (0%) Query: 75 GKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRD 134 G +GT + G Y+ + L + G+ L D +++ +AVR + +I+L G Sbjct: 14 GGLGTLMRELLPGHGYELRLLDLLPVEGEPDAIVADLADRDALREAVRGVDAIIHLAGIS 73 Query: 135 YETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEH-PKP 179 E K +++G + REEGV R + S +A + P+P Sbjct: 74 LEASFDKILAANIEGTYNLYEAAREEGVGRIVFASSNHAVGYTPRP 119 >UniRef50_A7H9M3 Cluster: NAD-dependent epimerase/dehydratase precursor; n=4; Cystobacterineae|Rep: NAD-dependent epimerase/dehydratase precursor - Anaeromyxobacter sp. Fw109-5 Length = 347 Score = 37.5 bits (83), Expect = 0.61 Identities = 33/110 (30%), Positives = 53/110 (48%), Gaps = 9/110 (8%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 V G TGF+G + L G +L L R A+RL +V+ L DE ++ Sbjct: 5 VTGATGFLGATLVPLLAAEGHRLRLLQRSAAPGAERLGA-----EVVRAS--LADEGAVR 57 Query: 119 KAVRYSNVVINLVGR-DYETKNFK-YNDVHVDGVRRIARICREEGVERFI 166 +AVR + V +L G+ D++ + ++HV G RR+ C G +R + Sbjct: 58 EAVRGVDAVYHLAGQVDFDPAEPRALYELHVQGTRRLLEACVAAGTKRVV 107 >UniRef50_A6G7N0 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=1; Plesiocystis pacifica SIR-1|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Plesiocystis pacifica SIR-1 Length = 373 Score = 37.5 bits (83), Expect = 0.61 Identities = 36/131 (27%), Positives = 59/131 (45%), Gaps = 11/131 (8%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVL--FTPYHLLDE-E 115 V G +GF+G ++C L + G + R A+ + G+V+ Y LD+ + Sbjct: 3 VTGASGFIGSHLCQVLRERGHAVQAMVRKTSKLAKLEDAAREGGRVIPFELAYASLDDVD 62 Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRI------ARICREEGVERFIHLS 169 ++ +AVR VV N+ G ++ +V GV + AR +G R +H+S Sbjct: 63 ALTEAVRGVEVVYNIAGTTAAFDRVGFDRTNVAGVDNLIAAIERARASEGKGPRRLVHVS 122 Query: 170 YLNA--EEHPK 178 L A HPK Sbjct: 123 SLMAAGPSHPK 133 >UniRef50_A1ZKR0 Cluster: Putative dihydroflavonol-4-reductase; n=1; Microscilla marina ATCC 23134|Rep: Putative dihydroflavonol-4-reductase - Microscilla marina ATCC 23134 Length = 328 Score = 37.5 bits (83), Expect = 0.61 Identities = 34/140 (24%), Positives = 65/140 (46%), Gaps = 10/140 (7%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDL-GQVLFTPYHLLDEESI 117 + GC+G VG ++ +L G + R D L D+ Q+ + +LD + Sbjct: 4 ITGCSGLVGSFIARRLLAAGHSVRALRRKD----SNLHYLTDIKDQIEWVEGDVLDVSRL 59 Query: 118 AKAVRYSNVVIN---LVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 174 ++ + VI+ LV +TK+ Y V+++G + I E GV++ + +S + A Sbjct: 60 YDVMQGAKQVIHSAALVSFTPKTKDLMYK-VNIEGTANVVNISLELGVDKLVFISSVAAL 118 Query: 175 EHPKPL-VLKKPSAWKISKY 193 K V+ + + W+ SK+ Sbjct: 119 GRRKNTEVIDEKAQWEPSKF 138 >UniRef50_Q9UXL5 Cluster: DTDP-glucose 4,6-dehydratase; n=1; Sulfolobus solfataricus|Rep: DTDP-glucose 4,6-dehydratase - Sulfolobus solfataricus Length = 317 Score = 37.5 bits (83), Expect = 0.61 Identities = 35/125 (28%), Positives = 59/125 (47%), Gaps = 9/125 (7%) Query: 182 LKKPSAWKISKYLGECAVREEYPT----ATIIRASDIYGSEDRFLRSLVNKMRSHSNL-- 235 LK S + SK + V+ T A I+R S+ YG +F L+ K + L Sbjct: 132 LKPSSPYSASKASADLFVKAYVRTYGISAVIVRPSNNYGPR-QFPEKLIPKAIIRTLLGI 190 Query: 236 -MPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLM 294 +P+Y +G A + +FV D A+ I + + K EVY G +RY + +++ ++ Sbjct: 191 HIPVYGDGKAE-RDWIFVEDTARIIFDVVSRAEWKGEVYNIPGGQRYNVLEILKMLEEVS 249 Query: 295 RKDEK 299 K+ K Sbjct: 250 GKEVK 254 >UniRef50_A0B7R7 Cluster: DTDP-4-dehydrorhamnose reductase; n=1; Methanosaeta thermophila PT|Rep: DTDP-4-dehydrorhamnose reductase - Methanosaeta thermophila (strain DSM 6194 / PT) (Methanothrixthermophila (strain DSM 6194 / PT)) Length = 281 Score = 37.5 bits (83), Expect = 0.61 Identities = 36/122 (29%), Positives = 58/122 (47%), Gaps = 12/122 (9%) Query: 145 VHVDGVRRIARICREEGVERFIHLS--YLNAEEHPKPLVLKKP----SAWKISKYLGECA 198 V+ G R A R G +F+H+S Y+ + P V P + + SK LGE Sbjct: 75 VNAIGARNAAIAARRAGA-KFVHISTDYVFDGKKDGPYVEYDPPNPLNVYGWSKLLGERM 133 Query: 199 VREEYPTATIIRASDIYGSEDR-FLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQ 257 V E+ P + I+R + +YG R F++++++ R+ L + + T P F DVA Sbjct: 134 VLEQNPDSFILRVAWLYGPAGRNFVKTMLSLARARDELR-VVNDQRGT---PTFAGDVAN 189 Query: 258 GI 259 I Sbjct: 190 QI 191 >UniRef50_Q8KB45 Cluster: NAD-dependent epimerase/dehydratase family protein/3-beta hydroxysteroid dehydrogenase/isomerase family protein; n=11; Chlorobiaceae|Rep: NAD-dependent epimerase/dehydratase family protein/3-beta hydroxysteroid dehydrogenase/isomerase family protein - Chlorobium tepidum Length = 335 Score = 37.1 bits (82), Expect = 0.81 Identities = 56/244 (22%), Positives = 101/244 (41%), Gaps = 17/244 (6%) Query: 56 VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 115 V V G TGF+G + + L G ++ + R + + +V Y D E Sbjct: 6 VILVTGSTGFIGSRMVDALVGQGRRVRVLLRPESRSTLSAGYREGVEEVC-AAYG--DPE 62 Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREE--GVERFIHLSYLNA 173 ++ +AV +I+L G + + +V V + + G+ RF+ +S L A Sbjct: 63 ALGRAVSGVASIIHLAGVTKAVDEAGFAEGNVRPVENLLEAVKRHNPGLGRFLLVSSLAA 122 Query: 174 ---EEHPKPLVLK----KP-SAWKISKYLGECAVREEYPTA--TIIRASDIYGSEDRFLR 223 P P V++ +P SA+ SK LGE R + TI+R +YG DR + Sbjct: 123 MGPASSPSPGVMESDRPRPVSAYGRSKLLGEAVARRHAGSVPLTIVRPPAVYGPGDRDIL 182 Query: 224 SLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLL 283 + M++ L G + V ++ +GI+ A ++ + Y P+ Y Sbjct: 183 EVFTMMKNGYLLSA--GPGRRQRFSMIHVDELIRGILLALDSENAAGQDYFITSPRGYAW 240 Query: 284 ADLV 287 +++ Sbjct: 241 DEVI 244 >UniRef50_Q11DG7 Cluster: NAD-dependent epimerase/dehydratase; n=1; Mesorhizobium sp. BNC1|Rep: NAD-dependent epimerase/dehydratase - Mesorhizobium sp. (strain BNC1) Length = 305 Score = 37.1 bits (82), Expect = 0.81 Identities = 42/165 (25%), Positives = 73/165 (44%), Gaps = 17/165 (10%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 V G TGF+GR++ L K G +++ R + A R GD+G T + + Sbjct: 6 VTGATGFIGRHLVPVLLKRGHEVVEVGRRTYESAGRFVAVGDIGPT--TDW--------S 55 Query: 119 KAVRYSNVVINLVGRDY--ETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEH 176 A+ + VI+L G + + + V+ G RR+A + G + + LS + A E Sbjct: 56 PALGGVDAVIHLAGLAHREDADEAMFFSVNDAGTRRLAEAAQAAGAKVLVALSSIAAREA 115 Query: 177 PKPLVLKKPSAWKISKYLGECAVR---EEYPTATIIRASDIYGSE 218 + +K +A+ SK E R E + ++R +YG + Sbjct: 116 EQN--PQKANAYGRSKLASEAHARSFAEGGGVSIVLRPPLVYGHD 158 >UniRef50_A4VPL6 Cluster: DTDP-4-dehydrorhamnose reductase; n=8; Proteobacteria|Rep: DTDP-4-dehydrorhamnose reductase - Pseudomonas stutzeri (strain A1501) Length = 306 Score = 37.1 bits (82), Expect = 0.81 Identities = 45/183 (24%), Positives = 74/183 (40%), Gaps = 21/183 (11%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 V G G VGR + + + G ++ P R A+ +V + Q E I Sbjct: 5 VCGAGGQVGRELVERASRFGLDVLAPARAQLDIAKPEQVADAMRQ---------RPELII 55 Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERF-IHLSYLNAEEHP 177 A Y++V + E+ + V+ DG R +A + GV F I Y+ + E Sbjct: 56 NAAAYTHV------DNAESHGEQAYAVNRDGPRHLAEAAKHAGVPLFHISTDYVFSGEAT 109 Query: 178 KPLVLKKPSA----WKISKYLGECAVREEYPTATIIRASDIYGSE-DRFLRSLVNKMRSH 232 +P + + SK GE A+R P I+R S +YG F+++++ R Sbjct: 110 RPYTESDETGPTGVYGASKLAGEEAIRSCLPAHLILRTSWVYGVHGHNFVKTMLRLARQR 169 Query: 233 SNL 235 L Sbjct: 170 DAL 172 >UniRef50_A1B7X9 Cluster: NAD-dependent epimerase/dehydratase; n=1; Paracoccus denitrificans PD1222|Rep: NAD-dependent epimerase/dehydratase - Paracoccus denitrificans (strain Pd 1222) Length = 302 Score = 37.1 bits (82), Expect = 0.81 Identities = 54/227 (23%), Positives = 96/227 (42%), Gaps = 35/227 (15%) Query: 54 GIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLD 113 G V G +GF+GR++C L G + + RG +A+R Q ++P Sbjct: 5 GSFVGVTGASGFIGRHLCADLRAAGLRPVAIGRGP--EAER--------QTDYSP----- 49 Query: 114 EESIAKAVRYSNVVINLVGR-----DYETKNFKYNDVHVDGVRRIARICREEGVERFIHL 168 ES+ A+ V++L GR D + + +V+ +AR + EGVER + Sbjct: 50 -ESLRAALAGCAAVVHLAGRRMTREDAPMELAPFLGPNVEATGHLARAAQAEGVERIVFA 108 Query: 169 SYLNAEEHPKPLVLKKP------SAWKISK-----YLGECAVREEYPTATIIRASDIYGS 217 S + P ++ +A+ +SK YL A + P A +R + +YG Sbjct: 109 STIAVYSAASPAPWREDGPVHPVNAYALSKLMAEHYLEMLARARQAPPALSLRFAAVYGH 168 Query: 218 EDRFLRSLVN--KMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNA 262 ++ +L+ + + L N T+ Q ++V+D I+ A Sbjct: 169 GEKGTPALMKFVNQAAAGETITLSGNPDYTIDQ-LYVTDATAAILAA 214 >UniRef50_A3LUX6 Cluster: Protein FMP52-1, mitochondrial precursor; n=2; Saccharomycetaceae|Rep: Protein FMP52-1, mitochondrial precursor - Pichia stipitis (Yeast) Length = 226 Score = 37.1 bits (82), Expect = 0.81 Identities = 35/131 (26%), Positives = 60/131 (45%), Gaps = 10/131 (7%) Query: 139 NFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECA 198 NFK D ++ A+ + GVE F+ +S + A L L+ + L E Sbjct: 85 NFKKIDYGIN--YEAAKAAKAAGVETFVLVSTIGANAQSSFLYLQ------VKGQLEEDI 136 Query: 199 VREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQG 258 + ++P I+R + G + + L+N + S L L+ L + P+F ++VAQ Sbjct: 137 IALKFPRTIILRPGILLGERETS-KGLLNNL-SVGVLKYLHGTPLTFLGNPIFGAEVAQI 194 Query: 259 IVNAARDDDTK 269 VNAA++ K Sbjct: 195 AVNAAQESFEK 205 >UniRef50_Q1H1D1 Cluster: NAD-dependent epimerase/dehydratase; n=1; Methylobacillus flagellatus KT|Rep: NAD-dependent epimerase/dehydratase - Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875) Length = 450 Score = 36.7 bits (81), Expect = 1.1 Identities = 43/171 (25%), Positives = 73/171 (42%), Gaps = 12/171 (7%) Query: 125 NVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPLVLKK 184 +VVIN VG E ++ +H + R C++ V I +S L A+E Sbjct: 86 DVVINAVGLLREHDGQTFDTLHEQAPAALFRACQQSQVGLVIQISALGADE-------AA 138 Query: 185 PSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLA 244 SA+ +SK + +R A I++ S ++G + R M + ++PL G Sbjct: 139 ASAYHLSKKAADDVLRTLDIPAFILQPSLVFGPDGSSARLFT--MLASMPVLPL-PGGGC 195 Query: 245 TVKQPVFVSDVAQGIVNAARDDDTKCEVYQAV-GPKRYLLADLVDWFYKLM 294 + QPV + D+ +V A + + AV GP+ L + D + M Sbjct: 196 QLLQPVHIHDLT-ALVQALTPLNPAGTITIAVAGPQALTLREYTDLLRRQM 245 >UniRef50_Q1ARG5 Cluster: DTDP-4-dehydrorhamnose reductase; n=1; Rubrobacter xylanophilus DSM 9941|Rep: DTDP-4-dehydrorhamnose reductase - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 278 Score = 36.7 bits (81), Expect = 1.1 Identities = 33/122 (27%), Positives = 55/122 (45%), Gaps = 11/122 (9%) Query: 145 VHVDGVRRIARICREEGVERFIHLS----YLNAEEHP-KPLVLKKP-SAWKISKYLGECA 198 V+ G R +A++C G E +H+S + E P +P P S + +K GE Sbjct: 79 VNALGPRNLAQLCERLGCE-LLHVSTNYVFDGRSERPYEPWDRPNPISVYGATKLAGEEY 137 Query: 199 VREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQG 258 VR I+R + +YG F+R+++ R S L ++ P + D+A G Sbjct: 138 VRHLTGRWYIVRTAGVYGEGRNFVRTMLRAARERSTLKVKDDEYIS----PTYARDLAGG 193 Query: 259 IV 260 I+ Sbjct: 194 II 195 >UniRef50_Q11CJ7 Cluster: NAD-dependent epimerase/dehydratase; n=5; Rhizobiales|Rep: NAD-dependent epimerase/dehydratase - Mesorhizobium sp. (strain BNC1) Length = 429 Score = 36.7 bits (81), Expect = 1.1 Identities = 52/229 (22%), Positives = 82/229 (35%), Gaps = 14/229 (6%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 V G TG +G VC +L G +I R G V + A Sbjct: 5 VTGATGLIGSTVCARLMSEGHHVIAVVR----PGSNPLPSGAAQIVEIDMARATGVQIWA 60 Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 178 + + V+N VG ++ VHV G + R C + R IH S + + Sbjct: 61 EHLFGVEAVVNCVGALQDSAREDTEGVHVTGAAALFRACERLSIRRVIHFSAIGVDR--- 117 Query: 179 PLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPL 238 +PSA+ +K G+ + E I+R S + G +L+ R S L Sbjct: 118 ----AQPSAFSATKLEGDHLLMERDLDWVILRPSVVLGRNVFGASALI---RGLSALPFA 170 Query: 239 YKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287 G Q V + DVA + + + GP+R + ++V Sbjct: 171 LSLGRTAPLQVVQLDDVAATVAFFIQPTAPVQVTLELAGPERLPMDEVV 219 >UniRef50_Q0M547 Cluster: NAD-dependent epimerase/dehydratase:3-beta hydroxysteroid dehydrogenase/isomerase:dTDP-4-dehydrorhamnose reductase:NmrA- like:Male sterility-like; n=2; Caulobacter|Rep: NAD-dependent epimerase/dehydratase:3-beta hydroxysteroid dehydrogenase/isomerase:dTDP-4-dehydrorhamnose reductase:NmrA- like:Male sterility-like - Caulobacter sp. K31 Length = 322 Score = 36.7 bits (81), Expect = 1.1 Identities = 50/186 (26%), Positives = 79/186 (42%), Gaps = 15/186 (8%) Query: 54 GIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLD 113 G V V G TGF+GR + L + G + + R D D + ++ L + Sbjct: 8 GPVVAVTGATGFLGRRLVRILAEEGWTVRVLARRDIADPAWRGL-----ELQLAIGDLAN 62 Query: 114 EESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA 173 ++A + VI++ G ++ +V+G R++A + G R + +S L A Sbjct: 63 PRALAALCDGAETVIHVAGLIKARSRAVFDKANVEGSRQVALAAKAAGA-RLVLVSSLAA 121 Query: 174 EEHPKPLVLKKPSAWKISKYLGECAVREEY-PTATIIRASDIYGSEDRFLRSLVNKMRSH 232 E P + S + SK GE A RE + TI+R IYG D L KM S Sbjct: 122 RE---PHL----SDYAGSKRGGEDAAREIFGADLTIVRPPAIYGPGDIETLRLF-KMASE 173 Query: 233 SNLMPL 238 +P+ Sbjct: 174 GAFLPV 179 >UniRef50_A3ACC5 Cluster: Putative uncharacterized protein; n=2; Oryza sativa|Rep: Putative uncharacterized protein - Oryza sativa subsp. japonica (Rice) Length = 272 Score = 36.7 bits (81), Expect = 1.1 Identities = 19/41 (46%), Positives = 26/41 (63%), Gaps = 1/41 (2%) Query: 248 QPVFVSDVAQGIVNAARDDDTKC-EVYQAVGPKRYLLADLV 287 QPV+V DVA IVN+ +DD T + Y GP+ Y + DL+ Sbjct: 144 QPVYVVDVAAAIVNSLKDDGTSMGKSYGLGGPEIYTVHDLL 184 >UniRef50_Q9HCX3 Cluster: Zinc finger protein 304; n=4; Homo sapiens|Rep: Zinc finger protein 304 - Homo sapiens (Human) Length = 659 Score = 36.7 bits (81), Expect = 1.1 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 5/91 (5%) Query: 85 YRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYND 144 ++GD YD Q L CGD G+ + LLD + VR + G ++ K+ N Sbjct: 213 HQGD-YDGQMLFSCGDEGKAFLDTFTLLDSQMTHAEVRPFRCL--PCGNVFKEKSALINH 269 Query: 145 VHVDGVRRIARICREEGVERFIHLSYLNAEE 175 + I+ +C+E G + FIHL +L + Sbjct: 270 RKIHS-GEISHVCKECG-KAFIHLHHLKMHQ 298 >UniRef50_Q8KB60 Cluster: Dihydroflavonol 4-reductase family; n=8; Chlorobiaceae|Rep: Dihydroflavonol 4-reductase family - Chlorobium tepidum Length = 333 Score = 36.3 bits (80), Expect = 1.4 Identities = 32/124 (25%), Positives = 56/124 (45%), Gaps = 6/124 (4%) Query: 53 NGIVATVFGCTGFVG-RYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHL 111 +GI + G TG++G R + + + + G + R + +L V + Sbjct: 2 SGIPILITGATGYIGARLLVDMIARYGDSVRC--RVTVREGSDASFLRNL-PVEIAQADM 58 Query: 112 LDEESIAKAVRYSNVVINLVGRDYETKNFKYN--DVHVDGVRRIARICREEGVERFIHLS 169 D ++ +AV+ + VV + G T+NF+ D +V G R I C E GV+R + S Sbjct: 59 HDPIAVNEAVKGAEVVFHCAGLIAYTRNFRNRLYDTNVLGTRHIVDACLEAGVKRLVATS 118 Query: 170 YLNA 173 + A Sbjct: 119 SIAA 122 >UniRef50_Q2FQM3 Cluster: Putative uncharacterized protein precursor; n=1; Methanospirillum hungatei JF-1|Rep: Putative uncharacterized protein precursor - Methanospirillum hungatei (strain JF-1 / DSM 864) Length = 345 Score = 36.3 bits (80), Expect = 1.4 Identities = 18/43 (41%), Positives = 22/43 (51%) Query: 135 YETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 177 Y N K D+ D R I RI REEG I + ++NAE P Sbjct: 161 YWNGNQKGQDLFKDAYRHIIRIMREEGASNLIWIYHVNAESQP 203 >UniRef50_Q8DE28 Cluster: Nucleoside-diphosphate-sugar epimerase; n=6; Proteobacteria|Rep: Nucleoside-diphosphate-sugar epimerase - Vibrio vulnificus Length = 303 Score = 35.9 bits (79), Expect = 1.9 Identities = 40/153 (26%), Positives = 69/153 (45%), Gaps = 17/153 (11%) Query: 125 NVVINLVG--RDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYL---NAEEHPKP 179 N +I+L G + + YN V+V G R+A E GV RF+ +S + +P Sbjct: 58 NTIIHLAGLAHSHSFSSKDYNRVNVAGTLRLATKAAEAGVRRFVFVSSIGVNGTSTQAEP 117 Query: 180 LVL-KKPSA---WKISKYLGECAV----REEYPTATIIRASDIYGSEDRFLRSLVNKMRS 231 L +PS + SKY E + +E I+R + +YG + ++ K+ Sbjct: 118 FALDSEPSPHNDYAQSKYDAEIGLKKIAKETGLEVVIVRPTLVYGPDAPGNFGMLTKLIK 177 Query: 232 HSNLMPLYKNGLATVKQP-VFVSDVAQGIVNAA 263 ++P GLAT ++ + V ++A +V A Sbjct: 178 RLPVLPF---GLATNRRDFISVQNLADLLVTCA 207 >UniRef50_Q3VWW5 Cluster: Dihydroflavonol 4-reductase family; n=2; Chlorobiaceae|Rep: Dihydroflavonol 4-reductase family - Prosthecochloris aestuarii DSM 271 Length = 341 Score = 35.9 bits (79), Expect = 1.9 Identities = 36/127 (28%), Positives = 54/127 (42%), Gaps = 12/127 (9%) Query: 53 NGIVATVFGCTGFVGRYVCNKLGKI---GTQL-ILPYRGDFYDAQRLKVCGDLGQVLFTP 108 +G V V G TG++G + +L + G L +L RG D L D V F Sbjct: 10 SGRVILVTGATGYIGSELVERLSSLCDAGLHLRVLARRGS--DVSVL----DGNSVEFVY 63 Query: 109 YHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYN--DVHVDGVRRIARICREEGVERFI 166 LLD S+ A + V + G ++N++ +V G + C EGV R + Sbjct: 64 GDLLDSLSLYDACSGVDTVFHCAGLIAYSRNYRQRLYATNVTGTGNLVNACLAEGVTRLV 123 Query: 167 HLSYLNA 173 H S + A Sbjct: 124 HTSSVAA 130 >UniRef50_A1ULW0 Cluster: NAD-dependent epimerase/dehydratase; n=4; Mycobacterium|Rep: NAD-dependent epimerase/dehydratase - Mycobacterium sp. (strain KMS) Length = 325 Score = 35.9 bits (79), Expect = 1.9 Identities = 50/211 (23%), Positives = 85/211 (40%), Gaps = 15/211 (7%) Query: 53 NGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLL 112 + I V G TG++G + L G Q+ R +L QV L+ Sbjct: 3 DNIRCLVTGATGYIGGRLVPALLDRGLQV----RAMARTPGKLDDAPWRAQVEVAKGDLM 58 Query: 113 DEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLN 172 D ES+A A +VV LV +KNF + + + ++ GV R ++LS L Sbjct: 59 DRESLAAAFEGMDVVYYLVHSMGTSKNFVAEE--AESAHNVVAAAKQAGVRRVVYLSGL- 115 Query: 173 AEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSH 232 HP+ + L + A + +GE + T +++A + GS ++ + Sbjct: 116 ---HPEGVELSRHLASRTE--VGEILIDSGIET-MVLQAGIVVGSGSASF-EMIRHLTDR 168 Query: 233 SNLMPLYKNGLATVKQPVFVSDVAQGIVNAA 263 +M K + QP+ + D +V AA Sbjct: 169 LPIMTAPK-WVHNKIQPISIDDALYYLVEAA 198 >UniRef50_A0QDT4 Cluster: Putative uncharacterized protein; n=1; Mycobacterium avium 104|Rep: Putative uncharacterized protein - Mycobacterium avium (strain 104) Length = 214 Score = 35.9 bits (79), Expect = 1.9 Identities = 34/112 (30%), Positives = 52/112 (46%), Gaps = 8/112 (7%) Query: 58 TVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 117 TVFG TG +GR+V L G R + +L+V + L D E++ Sbjct: 6 TVFGATGQIGRFVVADLLADGHAATAYVR----NPGKLQVADP--HLTVATGELSDAEAV 59 Query: 118 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLS 169 KAVR ++ VI+ +G ++ K V +G R I + E V R+I L+ Sbjct: 60 RKAVRGADAVISALGPSL-SRRAKGTPV-TEGTRNIVAAMQAEHVSRYIGLA 109 >UniRef50_Q0S304 Cluster: DTDP-4-dehydrorhamnose reductase; n=1; Rhodococcus sp. RHA1|Rep: DTDP-4-dehydrorhamnose reductase - Rhodococcus sp. (strain RHA1) Length = 262 Score = 35.5 bits (78), Expect = 2.5 Identities = 34/135 (25%), Positives = 56/135 (41%), Gaps = 11/135 (8%) Query: 159 EEGVERFIHLS--YLNAEEHPKPLVLKKPS----AWKISKYLGECAVREEYPTATIIRAS 212 +E R IH+S Y+ A + P + P+ A+ +K GE AV P+A ++R + Sbjct: 69 DEDTARLIHVSTDYVFAGQGDTPYEVDAPTGPATAYGRTKLAGERAVHAALPSAHVVRTA 128 Query: 213 DIY-GSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCE 271 +Y G F+ +++ R + + V P F D+A ++ A D Sbjct: 129 WVYTGVGSDFVSTMLRLERERDTVDVVDDQ----VGSPTFAGDLADALLELAGRSDVDAP 184 Query: 272 VYQAVGPKRYLLADL 286 V A R DL Sbjct: 185 VLHATNSGRASWFDL 199 >UniRef50_Q0BVL3 Cluster: NADH-ubiquinone oxidoreductase 39-40 kDa subunit-like protein; n=1; Granulibacter bethesdensis CGDNIH1|Rep: NADH-ubiquinone oxidoreductase 39-40 kDa subunit-like protein - Granulobacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1) Length = 323 Score = 35.5 bits (78), Expect = 2.5 Identities = 53/210 (25%), Positives = 91/210 (43%), Gaps = 17/210 (8%) Query: 56 VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 115 +A V G TGF+G + L + G + R + + D G + P L DE Sbjct: 7 IAAVTGATGFLGCHTVAALAERGFHV----RALIRRPEPHPLWQDRG-IETVPGDLADET 61 Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARIC-REEGVERFIHLSYLNAE 174 ++ + + ++VV++L G + V+ DG R+A + R R I +S L A Sbjct: 62 ALQRLLTGADVVLHLAGLVRARSPKAFLAVNRDGAFRLASMLQRCAPAARLIGISSLAAR 121 Query: 175 EHPKPLVLKKPSAWKISKYLGECAVREEY-PTATIIRASDIYGSEDRFLRSLVNKMRSHS 233 P + SA+ SK GE A+R+ + I+R IYG D S+ + + Sbjct: 122 ---APHL----SAYAASKSAGEQALRDGFGGKLCIVRPPVIYGPWDTATLSIFRS--AAA 172 Query: 234 NLMPLYKNGLATVKQPVFVSDVAQGIVNAA 263 ++P+ + + + + V+D A I A Sbjct: 173 RIVPVAGHSRSRIAM-IHVADAADAIAALA 201 >UniRef50_Q0AIT5 Cluster: NAD-dependent epimerase/dehydratase; n=3; Nitrosomonadaceae|Rep: NAD-dependent epimerase/dehydratase - Nitrosomonas eutropha (strain C71) Length = 307 Score = 35.5 bits (78), Expect = 2.5 Identities = 51/178 (28%), Positives = 82/178 (46%), Gaps = 23/178 (12%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYR--GDFYDAQRLK-VCGDLGQVLFTPYHLLDEE 115 V G TGF+GR + KL + G ++ R D+ ++ + GDLG L D Sbjct: 7 VTGATGFIGRILIAKLAESGWKIRALARCISSQKDSPFIEWISGDLG----CNNALRDLV 62 Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREE-GVERFIHLSYLNAE 174 S A+AV + V+ G+ ++ + +V G R I R+ + RF+H+S L A Sbjct: 63 SGAEAVIHCAGVVK--GKSWD----DFYQTNVIGTRNILRVASDSTSCSRFLHISSLAAR 116 Query: 175 EHPKPLVLKKPSAWKISKYLGECAV-REEYPTATII-RASDIYGSEDRFLRSLVNKMR 230 E PL+ S + SK+ E + R A++I R + +YG D+ + MR Sbjct: 117 E---PLL----SWYARSKFEAEEQIPRFSGRLASVIYRPAAVYGPGDKAMLPFFRSMR 167 >UniRef50_A6LP17 Cluster: NAD-dependent epimerase/dehydratase; n=1; Thermosipho melanesiensis BI429|Rep: NAD-dependent epimerase/dehydratase - Thermosipho melanesiensis BI429 Length = 335 Score = 35.5 bits (78), Expect = 2.5 Identities = 22/68 (32%), Positives = 38/68 (55%), Gaps = 3/68 (4%) Query: 113 DEESIAKAVRYSNVVINLVG--RDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSY 170 D E++ K R ++++I+L K K V+V+G R I IC + G +R I++S Sbjct: 53 DYETVKKFARNADLIIHLAAYISILPWKKKKVFSVNVNGTRNIINICMKTG-KRLIYVSS 111 Query: 171 LNAEEHPK 178 ++A E P+ Sbjct: 112 VHAFEEPR 119 >UniRef50_A5I358 Cluster: Molybdopterin biosynthesis protein; n=4; Clostridium botulinum|Rep: Molybdopterin biosynthesis protein - Clostridium botulinum A str. ATCC 3502 Length = 227 Score = 35.5 bits (78), Expect = 2.5 Identities = 30/117 (25%), Positives = 45/117 (38%), Gaps = 9/117 (7%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLK---VCGDLGQVLFTPYHLLDEE 115 V GC G +G Y+ LG+IG I GD + L + DL Sbjct: 26 VIGCGG-LGGYIIEMLGRIGVGHITAVDGDTFSESNLNRQIISSDLNLGKNKAIEAKKRM 84 Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRI-ARICREEGVER----FIH 167 + + Y N + + +D K +DV +D + I R +E E+ FIH Sbjct: 85 KVVNDLIYVNPITTFINKDNVLNILKEHDVVIDAIDNIETRFLLQESCEKLKIPFIH 141 >UniRef50_A0Z741 Cluster: Nucleoside-diphosphate-sugar epimerase; n=1; marine gamma proteobacterium HTCC2080|Rep: Nucleoside-diphosphate-sugar epimerase - marine gamma proteobacterium HTCC2080 Length = 299 Score = 35.5 bits (78), Expect = 2.5 Identities = 35/125 (28%), Positives = 59/125 (47%), Gaps = 15/125 (12%) Query: 126 VVINLVGRDYETKNFK-YNDVHVDGVRRIARICREEGVERFIHLSYLNAEE----HPKPL 180 VVI+ G + +F Y V+V+ R +A GV++FI +S LN P L Sbjct: 55 VVIHCAGIAHSKGDFSAYQQVNVEACRALASAAEVAGVKQFIFMSSLNVVPATIIDPGTL 114 Query: 181 VLKKP---SAWKISKYLGECAVREEYPTAT----IIRASDIYGSEDRFLRSLVNKMRSHS 233 + P S + SK+ E AV E +++ I+R + +Y DR L + + ++ Sbjct: 115 ASEIPEPLSPYAASKWQAEIAVSRELSSSSCELVILRPALVY---DRTLTANLAALKKWQ 171 Query: 234 NLMPL 238 L+P+ Sbjct: 172 RLLPV 176 >UniRef50_A3H8S6 Cluster: NAD-dependent epimerase/dehydratase; n=1; Caldivirga maquilingensis IC-167|Rep: NAD-dependent epimerase/dehydratase - Caldivirga maquilingensis IC-167 Length = 315 Score = 35.5 bits (78), Expect = 2.5 Identities = 49/169 (28%), Positives = 74/169 (43%), Gaps = 20/169 (11%) Query: 64 GFVGRYVCNKLGKIGTQLILPYRG-DFYDAQRLKVCGDLGQVLFTPYH-LLDEESIAKAV 121 GF+ +V L KIG Q+ + YR + + KV G V T + L DE+ + + Sbjct: 10 GFIATHVAEGLSKIG-QVTVTYRSLNGVNEVYAKVLR--GSVELTRLNPLTDEDELRGLI 66 Query: 122 RYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVE-RFIHLSYLNA------- 173 + S+ VINL+G VHV R++A + E +H+S N Sbjct: 67 KNSDTVINLIGALGNDAQL-LRTVHVVIPRQVASLIAEYSPSTMLVHVSASNVMGPIGKF 125 Query: 174 -EEHPKPLVLKKPSA-WKISKYLGECAVREEYPTA----TIIRASDIYG 216 E PK +PS ++ +K LGE V +A IIR + +YG Sbjct: 126 INEEPKHCEGARPSTPYEETKCLGEQVVYSMSQSAGFPLAIIRPTLVYG 174 >UniRef50_Q2S430 Cluster: Nucleoside-diphosphate-sugar epimerase; n=1; Salinibacter ruber DSM 13855|Rep: Nucleoside-diphosphate-sugar epimerase - Salinibacter ruber (strain DSM 13855) Length = 488 Score = 35.1 bits (77), Expect = 3.3 Identities = 34/127 (26%), Positives = 60/127 (47%), Gaps = 10/127 (7%) Query: 154 ARICREEGVERFIHLSYLNAEEH-PKPLVLKKPSAWKISKYLGECAVREEYPTATIIRAS 212 AR EGV++ ++L L E+ P P L++ ++ + LG +V T +RA Sbjct: 103 ARAAEAEGVDQILYLGALIPEDKSPLPSPLRR--RLEMEEVLGSTSV-----PLTTLRAG 155 Query: 213 DIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEV 272 I G+ +L L+N +R +M L + QP+ + DV +G+ + + +T Sbjct: 156 LIVGAGGTWLSMLLNLVR-RLPVMVL-PSWTRAETQPIALRDVVRGLEKSLGNPETYEAT 213 Query: 273 YQAVGPK 279 Y GP+ Sbjct: 214 YDVGGPE 220 >UniRef50_A0LKC0 Cluster: NAD-dependent epimerase/dehydratase; n=1; Syntrophobacter fumaroxidans MPOB|Rep: NAD-dependent epimerase/dehydratase - Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) Length = 312 Score = 35.1 bits (77), Expect = 3.3 Identities = 65/225 (28%), Positives = 95/225 (42%), Gaps = 22/225 (9%) Query: 55 IVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDE 114 IV + G GF+G + +L ++ + D A R + D V F + D Sbjct: 5 IVYLITGGAGFIGTNLIRRLSIPSVRIRVL---DNLSAGRREDL-DGFDVEFVQGDIQDA 60 Query: 115 ESIAKAVRYSNVVINLVGRD---YETKNFKYN-DVHVDGVRRIARICREEGVERFIHLSY 170 ++ +AV + VI+L N + N DV+V G + R E GVERF+ S Sbjct: 61 GAVHRAVAGARKVIHLAANTNVVQSVANPELNLDVNVRGTFNLLRASVEHGVERFVFAST 120 Query: 171 LNA--EEHPKPLVLKKP----SAWKISKYLGE--C-AVREEYPTATI-IRASDIYGSEDR 220 A + P+ P S + SK GE C A Y T+ +R S+IYG Sbjct: 121 GGAIVGDVTPPVHEDMPPNPISPYGASKLAGEGYCSAFWGAYGLPTVSLRFSNIYGPFSY 180 Query: 221 FLRSLVNK-MRSHSNLMPL--YKNGLATVKQPVFVSDVAQGIVNA 262 S++ K R PL Y +G T + +FV D+ QGI A Sbjct: 181 HKGSVIAKFFREVQAGKPLTIYGDGEQT-RDFLFVGDLCQGIARA 224 >UniRef50_Q8DJM2 Cluster: Nucleotide sugar epimerase; n=61; cellular organisms|Rep: Nucleotide sugar epimerase - Synechococcus elongatus (Thermosynechococcus elongatus) Length = 338 Score = 34.7 bits (76), Expect = 4.3 Identities = 35/125 (28%), Positives = 53/125 (42%), Gaps = 14/125 (11%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLI-LPYRGDFYDA-------QRLKVCGDLGQVLFTPYH 110 V G GF+G L + G ++I L D+YD + L + GQ +F Sbjct: 5 VTGVAGFIGHGAALALLRRGDRVIGLDNLNDYYDVNLKKSRLEHLNISSQPGQFIFRKID 64 Query: 111 LLDEESIAKAVR-YS-NVVINLV---GRDYETKN-FKYNDVHVDGVRRIARICREEGVER 164 L+D + + +S VI+L G Y +N F Y D ++ G I CR VE Sbjct: 65 LVDRLGVNQLFADFSPQKVIHLAAQAGVRYSLENPFAYIDSNIVGFLHILEACRHHRVEH 124 Query: 165 FIHLS 169 ++ S Sbjct: 125 LVYAS 129 >UniRef50_Q6LH31 Cluster: Putative uncharacterized protein CT0995; n=4; Vibrionales|Rep: Putative uncharacterized protein CT0995 - Photobacterium profundum (Photobacterium sp. (strain SS9)) Length = 287 Score = 34.7 bits (76), Expect = 4.3 Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 4/80 (5%) Query: 125 NVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPLVLKK 184 +VVI+ +G + Y DV + + GV +FI +S NAE++P +LK Sbjct: 70 DVVISCLGITRQRDGLGYMDVDYQANLNLLQEAERAGVSKFIDVSAFNAEKYPSVRLLKA 129 Query: 185 PSAWKI----SKYLGECAVR 200 + + S+ L C +R Sbjct: 130 KERFALRLLGSENLTPCVIR 149 >UniRef50_Q5WC54 Cluster: Putative uncharacterized protein; n=1; Bacillus clausii KSM-K16|Rep: Putative uncharacterized protein - Bacillus clausii (strain KSM-K16) Length = 1159 Score = 34.7 bits (76), Expect = 4.3 Identities = 17/57 (29%), Positives = 33/57 (57%), Gaps = 3/57 (5%) Query: 308 MKYDPILPLKVALVNAISPAYPLGNLHWEGIEREATSDNVVIGVPTLEDLGVTLTHM 364 + Y+ +L L L+ AIS A+ + WEG++ E T+ N G+ ++L +T++ + Sbjct: 1057 LAYELLLDLGETLLGAISCAFSIALAIWEGVDGEMTTSN---GMKLTQNLAITISQI 1110 >UniRef50_Q5FL85 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=5; Lactobacillus|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Lactobacillus acidophilus Length = 242 Score = 34.7 bits (76), Expect = 4.3 Identities = 16/39 (41%), Positives = 21/39 (53%) Query: 57 ATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRL 95 A VFG TG +G+ +C L + G L L Y +AQ L Sbjct: 4 AIVFGATGGIGKAICQDLAEDGWSLYLHYNTKMQEAQHL 42 >UniRef50_Q489H0 Cluster: Pseudouridine synthase; n=1; Colwellia psychrerythraea 34H|Rep: Pseudouridine synthase - Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibriopsychroerythus) Length = 567 Score = 34.7 bits (76), Expect = 4.3 Identities = 19/50 (38%), Positives = 27/50 (54%), Gaps = 3/50 (6%) Query: 68 RYVCN---KLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDE 114 RYV KL K ++ LP RGDF D + VC + G+ T + L++E Sbjct: 446 RYVATIEGKLEKTSGEICLPLRGDFDDRPKQMVCHEHGKYAETHWQLIEE 495 >UniRef50_Q1ARH9 Cluster: NmrA-like protein; n=1; Rubrobacter xylanophilus DSM 9941|Rep: NmrA-like protein - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 292 Score = 34.7 bits (76), Expect = 4.3 Identities = 25/68 (36%), Positives = 36/68 (52%), Gaps = 3/68 (4%) Query: 196 ECAVREEYPTATIIRASDIYGSE-DRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSD 254 E VR TI+R + IYGSE DR + L+ + S L P++ +G + QPV+ D Sbjct: 116 ERVVRSSGLEWTIVRPTMIYGSELDRNVHRLL-RFLDRSPLFPVFGSG-KNLWQPVYYED 173 Query: 255 VAQGIVNA 262 A+G A Sbjct: 174 CARGAFEA 181 >UniRef50_A5V7D1 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Sphingomonas wittichii RW1|Rep: Short-chain dehydrogenase/reductase SDR - Sphingomonas wittichii RW1 Length = 265 Score = 34.7 bits (76), Expect = 4.3 Identities = 15/33 (45%), Positives = 20/33 (60%) Query: 56 VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGD 88 VA V G +G +GR +C KL GT + L YR + Sbjct: 20 VALVIGGSGGIGRAICEKLAAAGTDVALTYRSN 52 >UniRef50_Q4QE34 Cluster: Putative uncharacterized protein; n=6; Trypanosomatidae|Rep: Putative uncharacterized protein - Leishmania major Length = 479 Score = 34.7 bits (76), Expect = 4.3 Identities = 30/109 (27%), Positives = 45/109 (41%), Gaps = 7/109 (6%) Query: 113 DEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLN 172 D + A S+ +I V E N ++DV + G ++ R ER I + L+ Sbjct: 152 DRIQVNVAANGSDTLIFAVDYHAEYANNSHHDVFLIGATNVSWTARSVRAERVIFCNGLD 211 Query: 173 AEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRF 221 A S + + GE AV +P ATIIR +YG R+ Sbjct: 212 A-------TFASESNYVDFRARGEDAVGANHPDATIIRFGPLYGKNYRY 253 >UniRef50_UPI0000D9CF92 Cluster: PREDICTED: DNA polymerase epsilon catalytic subunit; n=1; Macaca mulatta|Rep: PREDICTED: DNA polymerase epsilon catalytic subunit - Macaca mulatta Length = 1460 Score = 34.3 bits (75), Expect = 5.7 Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 6/81 (7%) Query: 156 ICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDI- 214 ICR ++RF+ L+Y EE P ++ S+W++ + E V EE+P I A I Sbjct: 795 ICR--AIQRFL-LAY--KEERRGPTLIAVQSSWELKRLASEIPVLEEFPLVPICVADKIN 849 Query: 215 YGSEDRFLRSLVNKMRSHSNL 235 YG D +R + NL Sbjct: 850 YGVLDWQRHGARRMIRHYLNL 870 >UniRef50_Q896Q0 Cluster: Transcriptional regulator, merR family; n=10; Firmicutes|Rep: Transcriptional regulator, merR family - Clostridium tetani Length = 284 Score = 34.3 bits (75), Expect = 5.7 Identities = 19/61 (31%), Positives = 32/61 (52%), Gaps = 3/61 (4%) Query: 292 KLMRKDEKWGGYIRYDMKYDPILPLKVALVNAISPAYPLGNLHWEGIEREATSDNVVIGV 351 K +RKDE ++Y++ + +VA + I P+Y + + WE I +E + NV G Sbjct: 120 KRLRKDED---AMKYNVTLKEMPKRQVASLREIIPSYEMEGILWEEIRKEMDAQNVQFGN 176 Query: 352 P 352 P Sbjct: 177 P 177 >UniRef50_Q6MRE5 Cluster: Dihydroflavonol-4-reductase; n=2; Bdellovibrio bacteriovorus|Rep: Dihydroflavonol-4-reductase - Bdellovibrio bacteriovorus Length = 330 Score = 34.3 bits (75), Expect = 5.7 Identities = 51/223 (22%), Positives = 94/223 (42%), Gaps = 29/223 (13%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQL--ILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEES 116 V G GF+G ++ L + G + ++ + D + + +K G V D S Sbjct: 6 VTGANGFLGSWLTKALLEEGHDVYALVRPKSDLSELEGVKCKYVHGDVT-------DVHS 58 Query: 117 IAKAVRYSNVVINLVGRDYETKNFK--YNDVHVDGVRRIARICREEGVERFIHLSYLNA- 173 + +A + + V +L G K+ + + V+V+G + +CRE V R ++LS + A Sbjct: 59 LLEATKGMDTVFHLAGVIAYKKSQRALMDKVNVEGTANVIAVCREHNVRRLVYLSSVVAI 118 Query: 174 -EEHPKPLVLKKPSAWKI---------SKYLGECAVR----EEYPTATIIRASDIYGSED 219 + +L + S + I +K+ E V+ + A ++ S IYG D Sbjct: 119 GAGYTPDQILNEESPYNIADLNLGYFETKHQAETLVKSACDKNEIDAVMLNPSTIYGRGD 178 Query: 220 RFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNA 262 S +++ + Y +G V V DV GI++A Sbjct: 179 AKKGSRKMQVKVAQGKLNFYTSGGVNV---VAAEDVVAGILSA 218 >UniRef50_Q2SJG1 Cluster: Nucleoside-diphosphate-sugar epimerase; n=1; Hahella chejuensis KCTC 2396|Rep: Nucleoside-diphosphate-sugar epimerase - Hahella chejuensis (strain KCTC 2396) Length = 305 Score = 34.3 bits (75), Expect = 5.7 Identities = 49/198 (24%), Positives = 85/198 (42%), Gaps = 26/198 (13%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 + GCTGFVG + + G + R Q G++ P + + + Sbjct: 5 ITGCTGFVGSALAAEAASRGYVVTGTSRSADQHPQFP------GKMELAPAY--ENDGWI 56 Query: 119 KAVRYSNVVINLVGRDYETKN------FKYNDVHVDGVRRIARICREEGVERFIHLSYL- 171 +R +V+I+ R ++ K ++ + + R +A + GV++FI+LS + Sbjct: 57 GLLRGVDVLIHCAARVHQVKEDAAEPLAEFRAANTEATRLLASWAVKAGVKKFIYLSTIK 116 Query: 172 -NAE-EHP-KPLVLKKP----SAWKISKYLGECAVREEYPTA----TIIRASDIYGSEDR 220 N E P +P P S + ISK+ GECA+RE A IIR +YG + Sbjct: 117 VNGEGSSPGRPFTPSDPPNPLSPYAISKWEGECALREVAAGAEMSYEIIRPPLVYGEGAK 176 Query: 221 FLRSLVNKMRSHSNLMPL 238 +++ K+ +PL Sbjct: 177 GNLAILEKLAKLRAPLPL 194 >UniRef50_Q8KNM3 Cluster: DTDP-6-deoxy-L-mannose-dehydrogenase; n=2; Aeromonas hydrophila|Rep: DTDP-6-deoxy-L-mannose-dehydrogenase - Aeromonas hydrophila Length = 300 Score = 34.3 bits (75), Expect = 5.7 Identities = 20/57 (35%), Positives = 32/57 (56%), Gaps = 6/57 (10%) Query: 175 EHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDR-FLRSLVNKMR 230 + P+PL + + +SKY GE A++ P IIR +YG E R F R+++ + R Sbjct: 119 DQPRPL-----NVYGMSKYAGELAIQRLCPHHLIIRTGWLYGGEGRHFARTILARAR 170 >UniRef50_Q2AZL1 Cluster: NAD-dependent epimerase/dehydratase:3-beta hydroxysteroid dehydrogenase/isomerase:Polysaccharide biosynthesis protein CapD:dTDP- 4-dehydrorhamnose reductase:Nucleotide sugar epimerase; n=3; Bacillus cereus group|Rep: NAD-dependent epimerase/dehydratase:3-beta hydroxysteroid dehydrogenase/isomerase:Polysaccharide biosynthesis protein CapD:dTDP- 4-dehydrorhamnose reductase:Nucleotide sugar epimerase - Bacillus weihenstephanensis KBAB4 Length = 307 Score = 34.3 bits (75), Expect = 5.7 Identities = 54/219 (24%), Positives = 102/219 (46%), Gaps = 27/219 (12%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 V G GF+G++V +L G ++I+ +D + K D V F +LD ++ Sbjct: 5 VIGGGGFIGKHVTKELIARGYEVII------FD--KFKPSMD---VPFEEIDILDIATLR 53 Query: 119 KAVRYSNVVINL---VGRDYETKNFK-YNDVHVDGVRRIARICREEGVERFIHLS----Y 170 + + + VI+L VG D N + V+ +G + I +C E G+ + + S Y Sbjct: 54 EKLINVDGVIHLAALVGVDNCRSNEEDVVRVNFEGTKNIVEVCIENGIGKLLFSSSSEVY 113 Query: 171 LNAEEHP-KPLVLKKP-SAWKISKYLGECAVREEYPTA---TIIRASDIYGSE--DRFLR 223 + P K +K P SA+ +K + E ++E + ++R ++YGS+ + F+ Sbjct: 114 GDGVSVPFKENDVKIPKSAYGKAKLMSEDFLKEYANNSFKVRVVRYFNVYGSQQNENFVI 173 Query: 224 SLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNA 262 S K + M +Y +G ++ ++SD+ G + A Sbjct: 174 SKFLKQAHNGENMTIYGDG-QQIRCFSYISDIVNGTILA 211 >UniRef50_Q1J1X7 Cluster: E3 binding; n=1; Deinococcus geothermalis DSM 11300|Rep: E3 binding - Deinococcus geothermalis (strain DSM 11300) Length = 445 Score = 34.3 bits (75), Expect = 5.7 Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 2/63 (3%) Query: 300 WGGYIRYDMKYDPILPLKVALVNAISPAYPLGNLHWEGIEREATSDNVVIGVPTLEDLGV 359 +G Y+R D P+ L+ L+ A+ PLG L +R A D + + ++DLGV Sbjct: 297 FGTYLRRDANLAPVTELRRQLIAALGQDVPLGLLVARAAQRHA--DRLGLNTVAVQDLGV 354 Query: 360 TLT 362 T Sbjct: 355 NQT 357 >UniRef50_Q048B8 Cluster: Glycerophosphoryl diester phosphodiesterase; n=2; Lactobacillus delbrueckii subsp. bulgaricus|Rep: Glycerophosphoryl diester phosphodiesterase - Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC BAA-365) Length = 473 Score = 34.3 bits (75), Expect = 5.7 Identities = 16/44 (36%), Positives = 25/44 (56%) Query: 138 KNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPLV 181 K+ Y D+ V +R+ IC++ G E F+ L Y+N E K +V Sbjct: 308 KDKVYEDLRVPTLRQYLEICKKYGKEAFLELKYINNMEALKEVV 351 >UniRef50_A7FRZ5 Cluster: RNA polymerase sigma-70 factor family; n=12; Clostridium|Rep: RNA polymerase sigma-70 factor family - Clostridium botulinum (strain ATCC 19397 / Type A) Length = 179 Score = 34.3 bits (75), Expect = 5.7 Identities = 18/59 (30%), Positives = 36/59 (61%), Gaps = 3/59 (5%) Query: 175 EHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIY-GSEDRFLRSLVNKMRSH 232 E+ PL+LK+ S W+I Y E V+ Y ++I+A +++ G E +F+ +N ++++ Sbjct: 21 ENFNPLILKEASRWRIGGYEYEDLVQHGY--LSVIKAVNMFKGEESKFVPYCINAIKTN 77 >UniRef50_A4JR88 Cluster: NmrA family protein; n=2; Proteobacteria|Rep: NmrA family protein - Burkholderia vietnamiensis (strain G4 / LMG 22486) (Burkholderiacepacia (strain R1808)) Length = 217 Score = 34.3 bits (75), Expect = 5.7 Identities = 35/156 (22%), Positives = 63/156 (40%), Gaps = 8/156 (5%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 +FG TG GR++ I L Y+ Y K+ G+V L D+ +IA Sbjct: 9 LFGATGPTGRHI------IEEALTQGYKLSVYTRDAKKLAPFAGRVEIVVGDLKDQRAIA 62 Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 178 K V+ ++ VI+ +G + + + + + G+ I + GV R I +S + Sbjct: 63 KCVQGADAVISALGPN--SLKVQGDKPIMRGLTNIIAAMKRAGVRRLIQISTAAYRDPKD 120 Query: 179 PLVLKKPSAWKISKYLGECAVREEYPTATIIRASDI 214 K + + K + + T +I SD+ Sbjct: 121 GFAFKAHAFALLFKVIASKGYEDIKATGELIANSDL 156 >UniRef50_A3TUE1 Cluster: Putative uncharacterized protein; n=3; Rhodobacteraceae|Rep: Putative uncharacterized protein - Oceanicola batsensis HTCC2597 Length = 288 Score = 34.3 bits (75), Expect = 5.7 Identities = 26/116 (22%), Positives = 51/116 (43%), Gaps = 8/116 (6%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 V G TG++GR++C + + G + R DA+R + D + + E++ Sbjct: 5 VAGATGYLGRFLCAEYARRGHHVTALVR----DARRAEGLAD----VLVEAEVTRPETLR 56 Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 174 + ++V++ +G + Y +V + R GV RF ++ LNA+ Sbjct: 57 GIMDGMDLVVSSLGITRQADGLGYLEVDFQANLNLLREAETAGVRRFAYVHVLNAD 112 >UniRef50_A1K6I8 Cluster: NADH dehydrogenase; n=3; Betaproteobacteria|Rep: NADH dehydrogenase - Azoarcus sp. (strain BH72) Length = 445 Score = 34.3 bits (75), Expect = 5.7 Identities = 55/225 (24%), Positives = 92/225 (40%), Gaps = 20/225 (8%) Query: 37 PNLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLK 96 P K GG + N +V G TGF+G + ++L + G QL R R Sbjct: 5 PRAVCKKVQHGGVRTVNVLVT---GATGFLGGSIVDRLLREGHQLRCAVRDPVAAVARRP 61 Query: 97 VCGDLGQVLFT-PY-HLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIA 154 G F Y H ++ + + VVIN VG E + +++ +H R + Sbjct: 62 -----GPAYFPLDYRHATTADAWREMLVGVEVVINAVGILREQGDQRFDLLHRAAPRALF 116 Query: 155 RICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDI 214 C E GV R + +S L A+ SA+ +SK + + AT+++ S + Sbjct: 117 DACVEAGVRRVLQISALGAD-------AGAASAYHLSKRAADDHLLALPLEATVVQPSLV 169 Query: 215 YGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGI 259 +G +L + S ++ L G + QPV V D+ + + Sbjct: 170 FGGAGA-STALFASLAS-MPVVALPGGGRQRI-QPVHVDDLVEAV 211 >UniRef50_A1BFY1 Cluster: NAD-dependent epimerase/dehydratase; n=10; Chlorobiaceae|Rep: NAD-dependent epimerase/dehydratase - Chlorobium phaeobacteroides (strain DSM 266) Length = 238 Score = 34.3 bits (75), Expect = 5.7 Identities = 37/152 (24%), Positives = 66/152 (43%), Gaps = 7/152 (4%) Query: 51 SFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYH 110 +F G V V G TG G+++ +L + L R + +++ G + + Sbjct: 4 TFKGTVLVV-GATGRTGQWIVRRLEEHHIPCHLFVRSS---EKAVELFGPEVEGHISTGS 59 Query: 111 LLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDV-HVDGVRRIARICREEGVERFIHLS 169 + + E I A+ +++ +I +G V DGV R+A + +++ + +FI +S Sbjct: 60 IENSEEIKSALEHADAIICAIGSSVTNPEEPPPSVIDRDGVIRLATLAKQKNIRKFILVS 119 Query: 170 YLNAEEHPKPLVLKKPSAWKISKYLGECAVRE 201 L + P L K K GE AVRE Sbjct: 120 SLAVTKPDHP--LNKYGNVLTMKLAGEDAVRE 149 >UniRef50_A0NIS8 Cluster: NADH dehydrogenase; n=2; Oenococcus oeni|Rep: NADH dehydrogenase - Oenococcus oeni ATCC BAA-1163 Length = 212 Score = 34.3 bits (75), Expect = 5.7 Identities = 47/216 (21%), Positives = 94/216 (43%), Gaps = 17/216 (7%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 VFG +GF+G+ + L K G +I R D+ K ++ + +L++ Sbjct: 7 VFGGSGFIGQKLLEILVKRGHDIISVSRHGRPDSLTEKWA---DKITWVSSDILNDHEWQ 63 Query: 119 KAVRYSNVVINLVGRDYET--KNFKYNDVHVDGVRRIARICREEGVE-RFIHLSYLNAEE 175 K V+ ++ +I+ VG +E KN Y+ V VR I + E RF+ +S Sbjct: 64 KYVKDADWIIDSVGILFENPKKNITYDRFIVQPVREITDFLKNNKSENRFLFIS-----A 118 Query: 176 HPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGS--EDRFLRSLVNKMRSHS 233 + P + +K + +KYL E + + I+ ++ S + +L ++ +H Sbjct: 119 NKGPFIFRK---YMEAKYLAEKITKRQNKNNLIVYPGLVFDSVKTSSIVITLPLRILNHI 175 Query: 234 NLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTK 269 L+ G +K+ ++++ I++ + TK Sbjct: 176 PLLNKVIIGYLPIKRVTLAKEISK-IIDGGQSIYTK 210 >UniRef50_Q4XFA1 Cluster: Putative uncharacterized protein; n=1; Plasmodium chabaudi|Rep: Putative uncharacterized protein - Plasmodium chabaudi Length = 61 Score = 34.3 bits (75), Expect = 5.7 Identities = 17/46 (36%), Positives = 25/46 (54%) Query: 30 NYSSDRKPNLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLG 75 NY S PNL+ KR SSF+ + A + CT + ++ NK+G Sbjct: 14 NYISIHHPNLSFLKRVENIASSFSILYAVICTCTSLIFPFLINKVG 59 >UniRef50_Q07864 Cluster: DNA polymerase epsilon catalytic subunit A; n=55; Eumetazoa|Rep: DNA polymerase epsilon catalytic subunit A - Homo sapiens (Human) Length = 2286 Score = 34.3 bits (75), Expect = 5.7 Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 6/81 (7%) Query: 156 ICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDI- 214 ICR ++RF+ L+Y EE P ++ S+W++ + E V EE+P I A I Sbjct: 1564 ICR--AIQRFL-LAY--KEERRGPTLIAVQSSWELKRLASEIPVLEEFPLVPICVADKIN 1618 Query: 215 YGSEDRFLRSLVNKMRSHSNL 235 YG D +R + NL Sbjct: 1619 YGVLDWQRHGARRMIRHYLNL 1639 >UniRef50_UPI0000E4A50F Cluster: PREDICTED: similar to Methionine adenosyltransferase II, beta; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Methionine adenosyltransferase II, beta - Strongylocentrotus purpuratus Length = 231 Score = 33.9 bits (74), Expect = 7.6 Identities = 35/126 (27%), Positives = 53/126 (42%), Gaps = 6/126 (4%) Query: 145 VHVDGVRRIARICREEGVER-FIHLSYLNAEEHP--KPLVLKKP-SAWKISKYLGECAVR 200 ++V IA +C + G+ +I +Y+ P KP P + + SK GE A Sbjct: 35 LNVGATAVIASVCEKLGILLVYISTNYVFDGTKPPYKPSDAPNPLNKYGQSKRDGEIATL 94 Query: 201 EEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQ--PVFVSDVAQG 258 E YP A I+R +YGS +R S + L +Q P V DVA Sbjct: 95 EHYPGAVILRLPLLYGSIERLNESAATYLLHQIQDDTSKVQDLCDYQQRRPTHVRDVASV 154 Query: 259 IVNAAR 264 ++ A+ Sbjct: 155 LLQLAQ 160 >UniRef50_Q7WAF7 Cluster: Putative oxidoreductase; n=3; Bordetella|Rep: Putative oxidoreductase - Bordetella parapertussis Length = 262 Score = 33.9 bits (74), Expect = 7.6 Identities = 20/70 (28%), Positives = 33/70 (47%), Gaps = 1/70 (1%) Query: 54 GIVATVFGCTGFVGRYVCNKLGKIGTQL-ILPYRGDFYDAQRLKVCGDLGQVLFTPYHLL 112 G VA + G G +G + G L +L R D + ++CG GQ + + Sbjct: 16 GRVALITGAAGGIGSAAALRFAAEGAALALLDRRPDAIEQLAGRICGQGGQAIGVAADVT 75 Query: 113 DEESIAKAVR 122 D++S+ +AVR Sbjct: 76 DDDSVRQAVR 85 >UniRef50_Q7UXZ2 Cluster: 3-beta-hydroxysteroid dehydrogenase; n=2; Planctomycetaceae|Rep: 3-beta-hydroxysteroid dehydrogenase - Rhodopirellula baltica Length = 339 Score = 33.9 bits (74), Expect = 7.6 Identities = 29/112 (25%), Positives = 54/112 (48%), Gaps = 8/112 (7%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118 V GC+GF+G + +L + +++ R + D R + G LLD E +A Sbjct: 6 VTGCSGFLGGEIVRQLLQRDCEVVGLSRRETADLVRAGMTHHRGD-------LLDTEYLA 58 Query: 119 KAVRYSNVVINLVGRDYETKNFK-YNDVHVDGVRRIARICREEGVERFIHLS 169 + + ++VVI+ +++ Y D +V R + + C+E GV + I+ S Sbjct: 59 RVIAGADVVIHTAAVAGVWGSWQHYFDNNVVASRNVLQACQELGVSQLIYTS 110 >UniRef50_A0LUB4 Cluster: Uncharacterised conserved protein UCP033563; n=1; Acidothermus cellulolyticus 11B|Rep: Uncharacterised conserved protein UCP033563 - Acidothermus cellulolyticus (strain ATCC 43068 / 11B) Length = 426 Score = 33.9 bits (74), Expect = 7.6 Identities = 15/32 (46%), Positives = 23/32 (71%), Gaps = 3/32 (9%) Query: 84 PYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 115 P+RG YDA R+ GD+G+VL PY ++D++ Sbjct: 14 PFRGIRYDAARV---GDIGRVLAPPYDVIDDD 42 >UniRef50_Q3KN81 Cluster: Leucoanthocyanidin reductase; n=3; Spermatophyta|Rep: Leucoanthocyanidin reductase - Pinus taeda (Loblolly pine) Length = 359 Score = 33.9 bits (74), Expect = 7.6 Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 5/77 (6%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQR--LKVCGDLG-QVLFTPYHLLDEE 115 + G TGF+GR+V K G R ++ ++ D G QV++ H D Sbjct: 62 IIGATGFIGRFVAEASVKSGRPTYALVRPTTLSSKPKVIQSLVDSGIQVVYGCLH--DHN 119 Query: 116 SIAKAVRYSNVVINLVG 132 S+ KA+R +VVI+ VG Sbjct: 120 SLVKAIRQVDVVISTVG 136 >UniRef50_O22856 Cluster: Putative sterol dehydrogenase; n=1; Arabidopsis thaliana|Rep: Putative sterol dehydrogenase - Arabidopsis thaliana (Mouse-ear cress) Length = 561 Score = 33.9 bits (74), Expect = 7.6 Identities = 30/117 (25%), Positives = 49/117 (41%), Gaps = 6/117 (5%) Query: 59 VFGCTGFVGRYVCNKLGKIGTQLI-LPYRGDFYDAQR----LKVCGDLGQVLFTPYHLLD 113 V G GF+GR + ++L ++G + + G L+ G+ + + D Sbjct: 17 VLGGRGFIGRSLVSRLLRLGNWTVRVADSGHTLHLDESDSLLEDALSSGRASYHCVDVRD 76 Query: 114 EESIAKAVRYSNVVINLVGRDYETKN-FKYNDVHVDGVRRIARICREEGVERFIHLS 169 + I K S VV + D + + F V V G R + CRE GV + I+ S Sbjct: 77 KPQIVKVTEGSYVVFYMGATDLRSHDYFDCYKVIVQGTRNVISACRESGVRKLIYNS 133 >UniRef50_Q178F4 Cluster: Mpv17 protein; n=5; Endopterygota|Rep: Mpv17 protein - Aedes aegypti (Yellowfever mosquito) Length = 226 Score = 33.9 bits (74), Expect = 7.6 Identities = 19/45 (42%), Positives = 27/45 (60%), Gaps = 2/45 (4%) Query: 221 FLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARD 265 FL+ V+++RS+ +L LYK L VK PV V V GI+ + D Sbjct: 14 FLKLPVSRIRSNMSLSSLYKRAL--VKYPVLVQSVQSGILMGSGD 56 >UniRef50_Q04304 Cluster: Uncharacterized protein YMR090W; n=5; Saccharomycetales|Rep: Uncharacterized protein YMR090W - Saccharomyces cerevisiae (Baker's yeast) Length = 227 Score = 33.9 bits (74), Expect = 7.6 Identities = 38/180 (21%), Positives = 75/180 (41%), Gaps = 7/180 (3%) Query: 59 VFGCTGFVGRYVCNKL---GKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 115 V G +G VGR + N+L T L + D + + +V D T Sbjct: 8 VVGASGKVGRLLINQLKANDSFSTPLAIVRTQDQVNYFKNEVGVDAS---LTDIENASVS 64 Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 175 I A++ + V+ G + + V +DG ++ C + G++RF+ +S L AE+ Sbjct: 65 EITDAIKAYDAVVFSAGAGGKGMERIFT-VDLDGCIKVVEACEKAGIKRFVVVSALKAED 123 Query: 176 HPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNL 235 +K + I+K + VR TI++ + ++ L ++K+ +++ Sbjct: 124 RDFWYNIKGLREYYIAKRSADREVRNSNLDYTILQPGSLELNKGTGLLQPLDKLEEKASV 183 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.320 0.138 0.419 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 465,557,984 Number of Sequences: 1657284 Number of extensions: 20300059 Number of successful extensions: 42190 Number of sequences better than 10.0: 189 Number of HSP's better than 10.0 without gapping: 67 Number of HSP's successfully gapped in prelim test: 122 Number of HSP's that attempted gapping in prelim test: 41896 Number of HSP's gapped (non-prelim): 213 length of query: 399 length of database: 575,637,011 effective HSP length: 102 effective length of query: 297 effective length of database: 406,594,043 effective search space: 120758430771 effective search space used: 120758430771 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.8 bits) S2: 74 (33.9 bits)
- SilkBase 1999-2023 -