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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000897-TA|BGIBMGA000897-PA|IPR001509|NAD-dependent
epimerase/dehydratase
         (399 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI0000D55D4F Cluster: PREDICTED: similar to CG6020-PA;...   489   e-137
UniRef50_Q9VPE2 Cluster: CG6020-PA; n=7; Endopterygota|Rep: CG60...   483   e-135
UniRef50_Q5DCH0 Cluster: SJCHGC05906 protein; n=1; Schistosoma j...   302   9e-81
UniRef50_A7SNV3 Cluster: Predicted protein; n=1; Nematostella ve...   283   4e-75
UniRef50_Q9N3H3 Cluster: Putative uncharacterized protein; n=2; ...   265   2e-69
UniRef50_Q16795 Cluster: NADH dehydrogenase [ubiquinone] 1 alpha...   255   2e-66
UniRef50_UPI0000E48350 Cluster: PREDICTED: similar to MGC64316 p...   244   2e-63
UniRef50_A4S3R8 Cluster: Predicted protein; n=1; Ostreococcus lu...   213   9e-54
UniRef50_Q4PHN2 Cluster: Putative uncharacterized protein; n=1; ...   194   5e-48
UniRef50_A7Q1K0 Cluster: Chromosome chr7 scaffold_44, whole geno...   193   6e-48
UniRef50_P25284 Cluster: NADH-ubiquinone oxidoreductase 40 kDa s...   191   3e-47
UniRef50_Q6C7X4 Cluster: Similar to tr|Q86ZJ8 Podospora anserina...   190   7e-47
UniRef50_A2QSH0 Cluster: Catalytic activity: NADH + ubiquinone =...   181   3e-44
UniRef50_Q6V506 Cluster: Putative NADH:ubiquinone oxidoreductase...   174   4e-42
UniRef50_Q559Z0 Cluster: Putative uncharacterized protein; n=2; ...   165   2e-39
UniRef50_Q5KJ08 Cluster: NADH dehydrogenase (Ubiquinone), putati...   164   3e-39
UniRef50_Q5AJA9 Cluster: Potential mitochondrial Complex I, 40kd...   161   3e-38
UniRef50_UPI00006CB9E4 Cluster: hypothetical protein TTHERM_0055...   136   1e-30
UniRef50_A7HPI7 Cluster: NAD-dependent epimerase/dehydratase; n=...   115   2e-24
UniRef50_Q1GR77 Cluster: 3-beta hydroxysteroid dehydrogenase/iso...   114   4e-24
UniRef50_Q2GE21 Cluster: NADH-ubiquinone oxidoreductase family p...   113   6e-24
UniRef50_Q3YT69 Cluster: NADH-ubiquinone oxidoreductase, putativ...   112   1e-23
UniRef50_A4GHP1 Cluster: NADH-ubiquinone oxidoreductase; n=2; Ba...   112   2e-23
UniRef50_A4WW99 Cluster: NADH dehydrogenase; n=5; Rhodobacterale...   111   4e-23
UniRef50_A0BZW4 Cluster: Chromosome undetermined scaffold_14, wh...   110   5e-23
UniRef50_Q3JEV6 Cluster: NAD-dependent epimerase/dehydratase; n=...   109   1e-22
UniRef50_Q0BUA2 Cluster: NADH-ubiquinone oxidoreductase 39-40 kD...   109   2e-22
UniRef50_Q2RYH4 Cluster: 3-beta-hydroxy-delta(5)-steroid dehydro...   107   4e-22
UniRef50_Q1GCR4 Cluster: 3-beta hydroxysteroid dehydrogenase/iso...   107   5e-22
UniRef50_Q38CX2 Cluster: Putative uncharacterized protein; n=5; ...   106   1e-21
UniRef50_A7DMA8 Cluster: NAD-dependent epimerase/dehydratase; n=...   101   3e-20
UniRef50_Q98CD7 Cluster: NADH dehydrogenase (Ubiquinone) 1 alpha...    97   5e-19
UniRef50_Q4FNB8 Cluster: Probable NADH-ubiquinone oxireductase; ...    95   4e-18
UniRef50_Q2GII8 Cluster: NADH-ubiquinone oxidoreductase family p...    93   9e-18
UniRef50_Q0ACP9 Cluster: NAD-dependent epimerase/dehydratase; n=...    92   3e-17
UniRef50_Q125I6 Cluster: NAD-dependent epimerase/dehydratase; n=...    90   8e-17
UniRef50_Q1GZ10 Cluster: NAD-dependent epimerase/dehydratase; n=...    90   1e-16
UniRef50_Q6G583 Cluster: NADH-ubiquinone oxidoreductase; n=3; Ba...    89   1e-16
UniRef50_A1WZI3 Cluster: NAD-dependent epimerase/dehydratase; n=...    87   1e-15
UniRef50_A6GU58 Cluster: NAD-dependent epimerase/dehydratase; n=...    85   3e-15
UniRef50_A6FZ88 Cluster: Probable NADH-ubiquinone oxidoreductase...    85   3e-15
UniRef50_Q1PXS0 Cluster: Similar to dehydratase OleE [Streptomyc...    84   5e-15
UniRef50_Q1YEV9 Cluster: NADH-ubiquinone oxidoreductase; n=7; Al...    82   2e-14
UniRef50_A5P8M1 Cluster: NADH ubiquinone oxidoreductase, putativ...    82   2e-14
UniRef50_Q5FPV9 Cluster: Putative oxidoreductase; n=1; Gluconoba...    82   3e-14
UniRef50_A4T0E5 Cluster: NAD-dependent epimerase/dehydratase; n=...    81   7e-14
UniRef50_Q0F0X9 Cluster: NAD-dependent epimerase/dehydratase; n=...    80   9e-14
UniRef50_UPI0000E87D4F Cluster: NAD-dependent epimerase/dehydrat...    79   2e-13
UniRef50_UPI0000F21730 Cluster: PREDICTED: hypothetical protein;...    79   2e-13
UniRef50_A5FQ11 Cluster: NAD-dependent epimerase/dehydratase; n=...    77   6e-13
UniRef50_Q5P3S8 Cluster: Predicted nucleoside-diphosphate-sugar ...    77   8e-13
UniRef50_A0L6A2 Cluster: NAD-dependent epimerase/dehydratase; n=...    76   2e-12
UniRef50_A7BKW7 Cluster: NAD-dependent epimerase/dehydratase; n=...    75   3e-12
UniRef50_Q2Y682 Cluster: NAD-dependent epimerase/dehydratase; n=...    75   4e-12
UniRef50_Q1K3T7 Cluster: NAD-dependent epimerase/dehydratase; n=...    75   4e-12
UniRef50_Q1WMR0 Cluster: Putative nucleoside-diphosphate-sugar e...    74   6e-12
UniRef50_Q3JE30 Cluster: NAD-dependent epimerase/dehydratase; n=...    74   8e-12
UniRef50_Q7NWF7 Cluster: Probable NADH-ubiquinone oxidoreductase...    73   1e-11
UniRef50_Q39C42 Cluster: NAD-dependent epimerase/dehydratase; n=...    73   2e-11
UniRef50_A3ES38 Cluster: Putative nucleoside-diphosphate-sugar e...    71   4e-11
UniRef50_Q560L2 Cluster: Putative uncharacterized protein; n=2; ...    71   4e-11
UniRef50_Q67SF4 Cluster: Putative NADH-ubiquinone oxidoreductase...    70   9e-11
UniRef50_Q7NF91 Cluster: Gll3635 protein; n=1; Gloeobacter viola...    69   2e-10
UniRef50_Q476T1 Cluster: NAD-dependent epimerase/dehydratase:3-b...    67   7e-10
UniRef50_Q746J9 Cluster: NADH-ubiquinone oxidoreductase 39 kDa s...    66   1e-09
UniRef50_Q31J38 Cluster: NAD-dependent epimerase/dehydratase; n=...    66   1e-09
UniRef50_Q74G63 Cluster: NADH dehydrogenase subunit, putative; n...    64   6e-09
UniRef50_Q1IZY4 Cluster: NAD-dependent epimerase/dehydratase; n=...    62   2e-08
UniRef50_Q9HNV3 Cluster: NADH dehydrogenase/oxidoreductase-like ...    62   2e-08
UniRef50_Q3SGD6 Cluster: Nucleoside-diphosphate-sugar epimerases...    60   1e-07
UniRef50_UPI00015BC9D3 Cluster: UPI00015BC9D3 related cluster; n...    57   9e-07
UniRef50_Q4UMY6 Cluster: Putative oxidoreductase protein; n=15; ...    54   5e-06
UniRef50_Q0LC55 Cluster: NAD-dependent epimerase/dehydratase; n=...    54   5e-06
UniRef50_O54156 Cluster: Oxidoreductase; n=1; Streptomyces coeli...    54   9e-06
UniRef50_A0YYK8 Cluster: Oxidoreductase; n=1; Lyngbya sp. PCC 81...    53   1e-05
UniRef50_Q67KJ4 Cluster: Putative oxidoreductase; n=1; Symbiobac...    53   2e-05
UniRef50_Q3A8K9 Cluster: Nucleoside-diphosphate-sugar epimerases...    53   2e-05
UniRef50_O66532 Cluster: NADH dehydrogenase; n=2; Aquifex|Rep: N...    52   2e-05
UniRef50_Q2S702 Cluster: Predicted nucleoside-diphosphate-sugar ...    52   4e-05
UniRef50_A6TJS1 Cluster: 3-beta hydroxysteroid dehydrogenase/iso...    51   6e-05
UniRef50_Q6L130 Cluster: NADH-dependent oxidoreductase; n=2; The...    49   2e-04
UniRef50_Q7NW82 Cluster: Putative uncharacterized protein; n=1; ...    49   2e-04
UniRef50_Q5UYL1 Cluster: UDP-glucose 4-epimerase; n=5; Halobacte...    49   2e-04
UniRef50_A7DQP3 Cluster: 3-beta hydroxysteroid dehydrogenase/iso...    49   2e-04
UniRef50_A6DZS8 Cluster: NAD-dependent epimerase/dehydratase; n=...    48   6e-04
UniRef50_Q5NR25 Cluster: Predicted nucleoside-diphosphate-sugar ...    46   0.001
UniRef50_A2UCM7 Cluster: NAD-dependent epimerase/dehydratase; n=...    46   0.002
UniRef50_Q0LK91 Cluster: NAD-dependent epimerase/dehydratase; n=...    46   0.002
UniRef50_A1WAD5 Cluster: NAD-dependent epimerase/dehydratase; n=...    46   0.002
UniRef50_A7H7V8 Cluster: NAD-dependent epimerase/dehydratase; n=...    45   0.003
UniRef50_A7CTR2 Cluster: NAD-dependent epimerase/dehydratase; n=...    45   0.003
UniRef50_A1VGT7 Cluster: NAD-dependent epimerase/dehydratase; n=...    45   0.003
UniRef50_A0RYZ0 Cluster: Nucleoside-diphosphate-sugar epimerase;...    45   0.003
UniRef50_Q89WS9 Cluster: Bll0599 protein; n=1; Bradyrhizobium ja...    44   0.005
UniRef50_Q1YFT6 Cluster: Possible NAD-dependent epimerase/dehydr...    44   0.007
UniRef50_A3WA10 Cluster: Predicted nucleoside-diphosphate-sugar ...    44   0.007
UniRef50_A1ASP8 Cluster: NAD-dependent epimerase/dehydratase; n=...    44   0.009
UniRef50_A3YG10 Cluster: Putative uncharacterized protein; n=1; ...    43   0.012
UniRef50_Q8KDL0 Cluster: 3-beta hydroxysteroid dehydrogenase/iso...    42   0.022
UniRef50_A2C1Q9 Cluster: Putative uncharacterized protein; n=1; ...    42   0.022
UniRef50_Q2W798 Cluster: DTDP-6-deoxy-L-mannose-dehydrogenase; n...    42   0.038
UniRef50_Q2RKH0 Cluster: NAD-dependent epimerase/dehydratase; n=...    42   0.038
UniRef50_Q1LGK6 Cluster: NAD-dependent epimerase/dehydratase; n=...    42   0.038
UniRef50_A7BY73 Cluster: NAD-dependent epimerase/dehydratase; n=...    42   0.038
UniRef50_Q12VM5 Cluster: NAD-dependent epimerase/dehydratase; n=...    42   0.038
UniRef50_Q0C1U1 Cluster: Putative UDP-glucose 4-epimerase; n=1; ...    41   0.050
UniRef50_Q0ANG5 Cluster: NAD-dependent epimerase/dehydratase pre...    41   0.050
UniRef50_A3ZLP8 Cluster: NAD-dependent epimerase/dehydratase fam...    41   0.050
UniRef50_A0NYC5 Cluster: DTDP-glucose 4,6-dehydratase; n=1; Stap...    41   0.066
UniRef50_Q0S7J3 Cluster: Reductase; n=2; Nocardiaceae|Rep: Reduc...    40   0.12 
UniRef50_Q0DWQ7 Cluster: Cyclin-B1-2; n=6; Oryza sativa|Rep: Cyc...    40   0.12 
UniRef50_Q5ZVY7 Cluster: Oxidoreductase; n=4; Legionella pneumop...    40   0.15 
UniRef50_A0A018 Cluster: MoeS5; n=4; Actinomycetales|Rep: MoeS5 ...    40   0.15 
UniRef50_Q5V0D3 Cluster: DTDP-glucose-46-dehydratase; n=2; Halob...    40   0.15 
UniRef50_Q2W604 Cluster: Predicted nucleoside-diphosphate-sugar ...    39   0.20 
UniRef50_A1VMB7 Cluster: NAD-dependent epimerase/dehydratase; n=...    39   0.20 
UniRef50_Q73MR8 Cluster: Epimerase/dehydratase, putative; n=2; B...    39   0.27 
UniRef50_Q11Z70 Cluster: Nucleoside-diphosphate-sugar epimerase;...    39   0.27 
UniRef50_A7FIK2 Cluster: NAD-dependent epimerase/dehydratase fam...    39   0.27 
UniRef50_A4BUQ8 Cluster: DTDP-4-dehydrorhamnose reductase; n=3; ...    39   0.27 
UniRef50_A3CRA1 Cluster: DTDP-4-dehydrorhamnose 3,5-epimerase, p...    38   0.35 
UniRef50_Q9A4D7 Cluster: Putative uncharacterized protein; n=1; ...    38   0.46 
UniRef50_Q82X00 Cluster: Putative UDP-glucose 4-epimerase; n=1; ...    38   0.46 
UniRef50_Q2Y734 Cluster: NAD-dependent epimerase/dehydratase pre...    38   0.46 
UniRef50_Q2S3D1 Cluster: NAD-dependent epimerase/dehydratase fam...    38   0.46 
UniRef50_Q9X9X6 Cluster: Putative uncharacterized protein SCO189...    38   0.61 
UniRef50_A7H9M3 Cluster: NAD-dependent epimerase/dehydratase pre...    38   0.61 
UniRef50_A6G7N0 Cluster: Oxidoreductase, short chain dehydrogena...    38   0.61 
UniRef50_A1ZKR0 Cluster: Putative dihydroflavonol-4-reductase; n...    38   0.61 
UniRef50_Q9UXL5 Cluster: DTDP-glucose 4,6-dehydratase; n=1; Sulf...    38   0.61 
UniRef50_A0B7R7 Cluster: DTDP-4-dehydrorhamnose reductase; n=1; ...    38   0.61 
UniRef50_Q8KB45 Cluster: NAD-dependent epimerase/dehydratase fam...    37   0.81 
UniRef50_Q11DG7 Cluster: NAD-dependent epimerase/dehydratase; n=...    37   0.81 
UniRef50_A4VPL6 Cluster: DTDP-4-dehydrorhamnose reductase; n=8; ...    37   0.81 
UniRef50_A1B7X9 Cluster: NAD-dependent epimerase/dehydratase; n=...    37   0.81 
UniRef50_A3LUX6 Cluster: Protein FMP52-1, mitochondrial precurso...    37   0.81 
UniRef50_Q1H1D1 Cluster: NAD-dependent epimerase/dehydratase; n=...    37   1.1  
UniRef50_Q1ARG5 Cluster: DTDP-4-dehydrorhamnose reductase; n=1; ...    37   1.1  
UniRef50_Q11CJ7 Cluster: NAD-dependent epimerase/dehydratase; n=...    37   1.1  
UniRef50_Q0M547 Cluster: NAD-dependent epimerase/dehydratase:3-b...    37   1.1  
UniRef50_A3ACC5 Cluster: Putative uncharacterized protein; n=2; ...    37   1.1  
UniRef50_Q9HCX3 Cluster: Zinc finger protein 304; n=4; Homo sapi...    37   1.1  
UniRef50_Q8KB60 Cluster: Dihydroflavonol 4-reductase family; n=8...    36   1.4  
UniRef50_Q2FQM3 Cluster: Putative uncharacterized protein precur...    36   1.4  
UniRef50_Q8DE28 Cluster: Nucleoside-diphosphate-sugar epimerase;...    36   1.9  
UniRef50_Q3VWW5 Cluster: Dihydroflavonol 4-reductase family; n=2...    36   1.9  
UniRef50_A1ULW0 Cluster: NAD-dependent epimerase/dehydratase; n=...    36   1.9  
UniRef50_A0QDT4 Cluster: Putative uncharacterized protein; n=1; ...    36   1.9  
UniRef50_Q0S304 Cluster: DTDP-4-dehydrorhamnose reductase; n=1; ...    36   2.5  
UniRef50_Q0BVL3 Cluster: NADH-ubiquinone oxidoreductase 39-40 kD...    36   2.5  
UniRef50_Q0AIT5 Cluster: NAD-dependent epimerase/dehydratase; n=...    36   2.5  
UniRef50_A6LP17 Cluster: NAD-dependent epimerase/dehydratase; n=...    36   2.5  
UniRef50_A5I358 Cluster: Molybdopterin biosynthesis protein; n=4...    36   2.5  
UniRef50_A0Z741 Cluster: Nucleoside-diphosphate-sugar epimerase;...    36   2.5  
UniRef50_A3H8S6 Cluster: NAD-dependent epimerase/dehydratase; n=...    36   2.5  
UniRef50_Q2S430 Cluster: Nucleoside-diphosphate-sugar epimerase;...    35   3.3  
UniRef50_A0LKC0 Cluster: NAD-dependent epimerase/dehydratase; n=...    35   3.3  
UniRef50_Q8DJM2 Cluster: Nucleotide sugar epimerase; n=61; cellu...    35   4.3  
UniRef50_Q6LH31 Cluster: Putative uncharacterized protein CT0995...    35   4.3  
UniRef50_Q5WC54 Cluster: Putative uncharacterized protein; n=1; ...    35   4.3  
UniRef50_Q5FL85 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    35   4.3  
UniRef50_Q489H0 Cluster: Pseudouridine synthase; n=1; Colwellia ...    35   4.3  
UniRef50_Q1ARH9 Cluster: NmrA-like protein; n=1; Rubrobacter xyl...    35   4.3  
UniRef50_A5V7D1 Cluster: Short-chain dehydrogenase/reductase SDR...    35   4.3  
UniRef50_Q4QE34 Cluster: Putative uncharacterized protein; n=6; ...    35   4.3  
UniRef50_UPI0000D9CF92 Cluster: PREDICTED: DNA polymerase epsilo...    34   5.7  
UniRef50_Q896Q0 Cluster: Transcriptional regulator, merR family;...    34   5.7  
UniRef50_Q6MRE5 Cluster: Dihydroflavonol-4-reductase; n=2; Bdell...    34   5.7  
UniRef50_Q2SJG1 Cluster: Nucleoside-diphosphate-sugar epimerase;...    34   5.7  
UniRef50_Q8KNM3 Cluster: DTDP-6-deoxy-L-mannose-dehydrogenase; n...    34   5.7  
UniRef50_Q2AZL1 Cluster: NAD-dependent epimerase/dehydratase:3-b...    34   5.7  
UniRef50_Q1J1X7 Cluster: E3 binding; n=1; Deinococcus geothermal...    34   5.7  
UniRef50_Q048B8 Cluster: Glycerophosphoryl diester phosphodieste...    34   5.7  
UniRef50_A7FRZ5 Cluster: RNA polymerase sigma-70 factor family; ...    34   5.7  
UniRef50_A4JR88 Cluster: NmrA family protein; n=2; Proteobacteri...    34   5.7  
UniRef50_A3TUE1 Cluster: Putative uncharacterized protein; n=3; ...    34   5.7  
UniRef50_A1K6I8 Cluster: NADH dehydrogenase; n=3; Betaproteobact...    34   5.7  
UniRef50_A1BFY1 Cluster: NAD-dependent epimerase/dehydratase; n=...    34   5.7  
UniRef50_A0NIS8 Cluster: NADH dehydrogenase; n=2; Oenococcus oen...    34   5.7  
UniRef50_Q4XFA1 Cluster: Putative uncharacterized protein; n=1; ...    34   5.7  
UniRef50_Q07864 Cluster: DNA polymerase epsilon catalytic subuni...    34   5.7  
UniRef50_UPI0000E4A50F Cluster: PREDICTED: similar to Methionine...    34   7.6  
UniRef50_Q7WAF7 Cluster: Putative oxidoreductase; n=3; Bordetell...    34   7.6  
UniRef50_Q7UXZ2 Cluster: 3-beta-hydroxysteroid dehydrogenase; n=...    34   7.6  
UniRef50_A0LUB4 Cluster: Uncharacterised conserved protein UCP03...    34   7.6  
UniRef50_Q3KN81 Cluster: Leucoanthocyanidin reductase; n=3; Sper...    34   7.6  
UniRef50_O22856 Cluster: Putative sterol dehydrogenase; n=1; Ara...    34   7.6  
UniRef50_Q178F4 Cluster: Mpv17 protein; n=5; Endopterygota|Rep: ...    34   7.6  
UniRef50_Q04304 Cluster: Uncharacterized protein YMR090W; n=5; S...    34   7.6  

>UniRef50_UPI0000D55D4F Cluster: PREDICTED: similar to CG6020-PA;
           n=2; Endopterygota|Rep: PREDICTED: similar to CG6020-PA
           - Tribolium castaneum
          Length = 398

 Score =  489 bits (1207), Expect = e-137
 Identities = 231/379 (60%), Positives = 285/379 (75%), Gaps = 4/379 (1%)

Query: 19  GSMSVVYIKAANYSSDRKP-NLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKI 77
           G + + Y+K ANYS++ K  NL+A KRGTGGRSSFNGIVATVFGC GF+GRYVCN+LGK 
Sbjct: 17  GFIGIAYVKTANYSTESKAYNLSALKRGTGGRSSFNGIVATVFGCGGFIGRYVCNRLGKN 76

Query: 78  GTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYET 137
           G+QLILPYRGD YD  RLKVCGDLGQV F P+ L DEESI K  RYSNVVINL+GRD+ET
Sbjct: 77  GSQLILPYRGDPYDVMRLKVCGDLGQVYFHPFDLRDEESIEKVCRYSNVVINLIGRDWET 136

Query: 138 KNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGEC 197
           +NF ++DVHV G R +A++ +  GVERFIHLS LNAEE P+ ++LK  S +  SK+ GE 
Sbjct: 137 RNFSFDDVHVKGARLLAKVAKRSGVERFIHLSALNAEETPEAVILKGGSKFLASKWRGEQ 196

Query: 198 AVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQ 257
           AV EE+P ATI R +D+YG EDRFLR   +  R  +  +PL+K G  T+KQPVFVSD+A 
Sbjct: 197 AVLEEFPEATIFRPADVYGQEDRFLRYYGHIWRRQATYLPLWKKGEETIKQPVFVSDLAS 256

Query: 258 GIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMRKDEKWGGYIRYDMKYDPILPLK 317
           GI+ A +D DT  +VYQAVGPKRY L++LVDWF+++MRKD+ W GY RYDM+YDPI  ++
Sbjct: 257 GIMAALKDSDTAGKVYQAVGPKRYYLSELVDWFFRVMRKDKDW-GYWRYDMRYDPIFQIR 315

Query: 318 VALVNAISPAYPLGNLHWEGIEREATSDNVVIGVPTLEDLGVTLTHMEDQVPWELKPFR- 376
           V L   +   +P+GNLHWE +ERE  +D V   VPTLEDLGV LTHMEDQVPWELKP+  
Sbjct: 316 VTLTEKLRVGFPIGNLHWERVEREHVTDVVHSEVPTLEDLGVALTHMEDQVPWELKPYTY 375

Query: 377 -AHQYYMDRLGEFPKPDPP 394
             +Q  +D    +  P PP
Sbjct: 376 GLYQGLVDLEEPYTPPAPP 394


>UniRef50_Q9VPE2 Cluster: CG6020-PA; n=7; Endopterygota|Rep:
           CG6020-PA - Drosophila melanogaster (Fruit fly)
          Length = 416

 Score =  483 bits (1192), Expect = e-135
 Identities = 238/362 (65%), Positives = 271/362 (74%)

Query: 38  NLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKV 97
           N AA KRGTGGRSSFNGIVATVFG TGFVGRYVCNKLGK GTQ+ILPYRGD  D  RLKV
Sbjct: 47  NPAAMKRGTGGRSSFNGIVATVFGATGFVGRYVCNKLGKSGTQMILPYRGDDSDVIRLKV 106

Query: 98  CGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARIC 157
            GDLGQVLF  Y+L D  SI  AV++SNVVINLVGRD+ETKNFK+ DVHV+G  RIARI 
Sbjct: 107 TGDLGQVLFHFYNLEDPASIRDAVKHSNVVINLVGRDFETKNFKFKDVHVNGAERIARIA 166

Query: 158 REEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGS 217
           RE GVER IHLS LN E +PK L +K  S W  SKY GE  VR+ +P ATIIR +DIYGS
Sbjct: 167 REAGVERLIHLSSLNVEANPKDLYVKGGSEWLKSKYEGELRVRDAFPNATIIRPADIYGS 226

Query: 218 EDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVG 277
           EDRFLR   +  R     MPL+  G  TVKQPV+VSDVAQ I+NAA+D D+   +YQAVG
Sbjct: 227 EDRFLRYYAHIWRRQFRSMPLWHKGEKTVKQPVYVSDVAQAIINAAKDPDSAGRIYQAVG 286

Query: 278 PKRYLLADLVDWFYKLMRKDEKWGGYIRYDMKYDPILPLKVALVNAISPAYPLGNLHWEG 337
           PKRY L++LVDWF++LMRKD+K  GY+RYDM++DP   LK  L + I P  P+G LH   
Sbjct: 287 PKRYQLSELVDWFHRLMRKDQKRWGYMRYDMRWDPTFLLKAKLNSFICPGTPIGGLHPAR 346

Query: 338 IEREATSDNVVIGVPTLEDLGVTLTHMEDQVPWELKPFRAHQYYMDRLGEFPKPDPPPVY 397
           IEREA +D V+ GVPTLEDLGVTLT ME QVPWEL+P+RA  YY   LGEF  P PP   
Sbjct: 347 IEREAVTDKVLTGVPTLEDLGVTLTTMEQQVPWELRPYRAALYYDAELGEFETPSPPKCI 406

Query: 398 SA 399
            A
Sbjct: 407 EA 408


>UniRef50_Q5DCH0 Cluster: SJCHGC05906 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC05906 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 394

 Score =  302 bits (742), Expect = 9e-81
 Identities = 156/359 (43%), Positives = 232/359 (64%), Gaps = 14/359 (3%)

Query: 43  KRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLG 102
           KRGTGGR+SFNG+V TVFG TG++GR +   L K GTQ+I+PYR D +  + +KV GDLG
Sbjct: 42  KRGTGGRASFNGMVVTVFGATGYLGRVLMTHLAKTGTQIIVPYRCDPHMIRGMKVVGDLG 101

Query: 103 QVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGV 162
           Q+LF PY+L D+E + KA++YS+VVINL+G +++T+NF   +VH+D   RIA+I +E GV
Sbjct: 102 QILFLPYNLKDDECLRKAMKYSDVVINLIGTEFDTRNFTIEEVHIDAACRIAKISKEIGV 161

Query: 163 ERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFL 222
           E+ +H+S L   ++P+  V +KPS + ISK +GE  V  E P ATI R ++I+G  DRFL
Sbjct: 162 EQLVHVSALCQNKNPQKYV-RKPSRFMISKAIGEEEVLRERPDATIFRPAEIWGPLDRFL 220

Query: 223 RSLVNKMRSHSNL----MPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGP 278
               +K R H+ +    +PL+  G  T+KQPV+V D+A+GI+N   + ++  ++Y+AVGP
Sbjct: 221 CYFASKPRRHNGIQTVFVPLWSYGEHTIKQPVYVGDIARGIINCLHNPESLGQIYEAVGP 280

Query: 279 KRYLLADLVDWFYKLMRKDEKWGGYIRYDMKYDPILPLKVALVNAISPAYPLG-NLHWEG 337
            RY L D+V W Y + R       Y+  ++   P+ P  +A          +   L +E 
Sbjct: 281 HRYRLDDIVKWIYLICR-------YLPSEIYIIPMNPWFLARTYIYENLGRINPYLTFER 333

Query: 338 IEREATSDNVVIGVPTLEDLGVTLTHMEDQVPWELKPFRAHQYYMDRLGEFPKPDPPPV 396
           +ERE+ +D ++ G PTL+DL V LT +ED++   +  FR    Y   +GEFP+P PPP+
Sbjct: 334 LERESATD-ILSGCPTLDDLNVKLTKLEDRINHIVYLFRRDYNYWHAVGEFPEPPPPPI 391


>UniRef50_A7SNV3 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 372

 Score =  283 bits (695), Expect = 4e-75
 Identities = 153/347 (44%), Positives = 222/347 (63%), Gaps = 21/347 (6%)

Query: 43  KRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLG 102
           K+GTGGRSSFNG+ ATVFG TGF+GRYV N+LG++GTQL +PYRGD +D + L++ GDLG
Sbjct: 34  KKGTGGRSSFNGVSATVFGATGFLGRYVINRLGRVGTQLTVPYRGDEHDIRHLRLMGDLG 93

Query: 103 QVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGV 162
           Q+ F  +HL DEESIAK V++SNVV+NL+GR +ET+NF + +VHVDG R IA+  +E GV
Sbjct: 94  QIDFFDFHLKDEESIAKMVKHSNVVVNLIGRGFETRNFNFEEVHVDGARTIAKAAKEAGV 153

Query: 163 ERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFL 222
           ER IH+S LNA        +  PS +  +K LGE AVREE+P ATI+R   ++G ED+FL
Sbjct: 154 ERLIHVSALNA-------AVDSPSKFLHTKALGEQAVREEFPNATILRPGTVFGHEDKFL 206

Query: 223 RSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYL 282
            +    +RS    +PL + G+ T K PV+V+DVAQ I+ A +++ +  + ++ VGP  Y 
Sbjct: 207 -NYYAYLRSLPLGIPLIEGGMNTKKMPVYVADVAQSILEAIKEEASVGQTFELVGPSEYY 265

Query: 283 LADLVDWFYKLMRKDEKWGGYIRYDMKYDPILPLKVALVNAISPAYPLGN--LHWEGIER 340
           L D++D+ Y++M+ + K      Y       +P K   + A    + + N  L  + + R
Sbjct: 266 LYDIIDYIYRVMKCNFK-----HY------TVPRKAYELMAWGFEWSIFNPRLTRDMLYR 314

Query: 341 EATSDNVVIGVPTLEDLGVTLTHMEDQVPWELKPFRAHQYYMDRLGE 387
           +  SD +  G+P LEDLG+  T +  +    L+  R   YY + + E
Sbjct: 315 QFQSDALTPGLPGLEDLGIKPTPLGAEAIAVLRRHRQSYYYEEAIDE 361


>UniRef50_Q9N3H3 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 431

 Score =  265 bits (649), Expect = 2e-69
 Identities = 161/391 (41%), Positives = 220/391 (56%), Gaps = 7/391 (1%)

Query: 9   QATSKLLHLNGSMSVVYIKAANYSSDRKPNLAAYKRGTGGRSSFNGIVATVFGCTGFVGR 68
           QA S +   N S +V   + A+         A +++G GGR+SF+G V TVFG +GF+G 
Sbjct: 14  QAVSVVGSQNFSSAVTSAENAHPEPRVSSQSAQFRKGAGGRASFSGNVVTVFGASGFLGL 73

Query: 69  YVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKAVRYSNVVI 128
            V NK  K G+Q+I+PYR D Y  +  KV G+LGQVL+ P+ L+DEESI KAV+YSNVVI
Sbjct: 74  PVVNKFAKNGSQIIIPYRQDPYYMREHKVLGELGQVLYFPFELMDEESIRKAVKYSNVVI 133

Query: 129 NLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPLVLKKPSAW 188
           NL+G    T  + Y DV+  G RR+ARIC+E GVE+F+HLS L A   P+       S +
Sbjct: 134 NLIGTRVPTGKYNYYDVNDTGARRLARICKEMGVEKFVHLSALGATTQPQKGHFVAKSQF 193

Query: 189 KISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMR-SHSNLMPLYKNGLATVK 247
             SK LGE AVREE+P ATIIR S IYG  D F++  V++ R +  + + LYK G  T K
Sbjct: 194 LHSKGLGEVAVREEFPEATIIRPSVIYGELDGFIQYYVSRWRKTPLDYVYLYKKGEETYK 253

Query: 248 QPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMRKDEKWG-GYIRY 306
            P++V DVA GI +A  D   K   Y+ VGP  Y L++L+D+ YK       +G  Y R+
Sbjct: 254 MPIWVGDVAAGIQSAVNDPTAKGHTYEFVGPHCYQLSELIDFMYKKAHCLSDFGFRYKRH 313

Query: 307 DM--KYDPILPLKVALVNAISPAYPLGNLHWEGIEREATSDNVVIGVPTLEDLGV-TLTH 363
            M   Y   L +   L   +       N  W  +E      +++ G  TL DLGV  LT 
Sbjct: 314 GMPDPYFMALTMATELYGKVFKCKVPLNREW--MEFVEVQSDILTGERTLADLGVRRLTE 371

Query: 364 MEDQVPWELKPFRAHQYYMDRLGEFPKPDPP 394
            E     +      ++Y+ ++ GE P P  P
Sbjct: 372 FELAGGQQAFYRSFNRYFEEQYGELPAPSLP 402


>UniRef50_Q16795 Cluster: NADH dehydrogenase [ubiquinone] 1 alpha
           subcomplex subunit 9, mitochondrial precursor; n=38;
           Euteleostomi|Rep: NADH dehydrogenase [ubiquinone] 1
           alpha subcomplex subunit 9, mitochondrial precursor -
           Homo sapiens (Human)
          Length = 377

 Score =  255 bits (624), Expect = 2e-66
 Identities = 148/347 (42%), Positives = 215/347 (61%), Gaps = 20/347 (5%)

Query: 35  RKPNLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQR 94
           R+ + A    G GGRSS +GIVATVFG TGF+GRYV N LG++G+Q+I+PYR D YD   
Sbjct: 34  RQLHHALMPHGKGGRSSVSGIVATVFGATGFLGRYVVNHLGRMGSQVIIPYRCDKYDIMH 93

Query: 95  LKVCGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIA 154
           L+  GDLGQ+LF  +   D++SI + V++SNVVINL+GRD+ETKNF + DV V   + IA
Sbjct: 94  LRPMGDLGQLLFLEWDARDKDSIRRVVQHSNVVINLIGRDWETKNFDFEDVFVKIPQAIA 153

Query: 155 RICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDI 214
           ++ +E GVE+FIH+S+LNA        +K  S +  +K +GE  VR+ +P A I++ SDI
Sbjct: 154 QLSKEAGVEKFIHVSHLNAN-------IKSSSRYLRNKAVGEKVVRDAFPEAIIVKPSDI 206

Query: 215 YGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQ 274
           +G EDRFL S  +  R     +PL   G  TVKQPV+V DV++GIVNA +D D   + + 
Sbjct: 207 FGREDRFLNSFASMHR--FGPIPLGSLGWKTVKQPVYVVDVSKGIVNAVKDPDANGKSFA 264

Query: 275 AVGPKRYLLADLVDWFYKLMRKDEKWGGYIRYDMKYDPILPLK-VALVNAISPAYPLGNL 333
            VGP RYLL  LV + + +  +      ++ + +   P+   + VA V  ISP  P   +
Sbjct: 265 FVGPSRYLLFHLVKYIFAVAHR-----LFLPFPL---PLFAYRWVARVFEISPFEPW--I 314

Query: 334 HWEGIEREATSDNVVIGVPTLEDLGVTLTHMEDQVPWELKPFRAHQY 380
             + +ER   +D  +  +P LEDLG+  T +E +    L+  R +++
Sbjct: 315 TRDKVERMHITDMKLPHLPGLEDLGIQATPLELKAIEVLRRHRTYRW 361


>UniRef50_UPI0000E48350 Cluster: PREDICTED: similar to MGC64316
           protein; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to MGC64316 protein -
           Strongylocentrotus purpuratus
          Length = 378

 Score =  244 bits (598), Expect = 2e-63
 Identities = 135/338 (39%), Positives = 207/338 (61%), Gaps = 18/338 (5%)

Query: 44  RGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQ 103
           +G GGRSSF+GIVA VFG  GF+G+Y+ N+LG+ G+Q+++P+R D Y  Q +K+ GDLGQ
Sbjct: 45  KGRGGRSSFSGIVAAVFGGNGFLGKYIVNRLGREGSQVVVPHRCDEYYVQPMKLMGDLGQ 104

Query: 104 VLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVE 163
           ++F  Y+L   + I   V    VV+NL+ +DYET++F + D++++  R +A+IC+E GV 
Sbjct: 105 IMFRQYNLRQHDLIRDIVGNCTVVVNLLSKDYETRHFTFEDINIEAPRNLAKICKEAGVP 164

Query: 164 RFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLR 223
           R IH+S L A+       +  P+ +  +K  GE  VREE+P A I+R + ++G EDRF  
Sbjct: 165 RLIHVSALGAD-------MASPAKFLRTKAAGERVVREEFPEAVIVRPAQMFGREDRFFN 217

Query: 224 SLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLL 283
              N+ R     +PL+ +    VK+PV+VSDVAQ I++   + +   + Y+  GP  YLL
Sbjct: 218 HFANQ-RFFGG-VPLFPSARRVVKRPVYVSDVAQAIMSIINEKEADGKTYELAGPNGYLL 275

Query: 284 ADLVDWFYKLMRKDEKWGGYIRYDMKYDPILPLKVALVNAISPAYPLGNLHWEGIEREAT 343
            DLVD+ Y++ R+      YIRY +   PIL L +A    ++P  P   L  + +E + T
Sbjct: 276 TDLVDFIYRVTRRP-----YIRYPVP-RPILRL-IASGFELTPFDPF--LTRDMLELQHT 326

Query: 344 SDNVVIGVPTLEDLGVTLTHMEDQVPWELKPFRAHQYY 381
           +D V  G+P LEDL VT T +E      L+  R+ +Y+
Sbjct: 327 TDVVQSGMPGLEDLNVTPTTVEYAAIRGLRRHRSDRYF 364


>UniRef50_A4S3R8 Cluster: Predicted protein; n=1; Ostreococcus
           lucimarinus CCE9901|Rep: Predicted protein -
           Ostreococcus lucimarinus CCE9901
          Length = 366

 Score =  213 bits (519), Expect = 9e-54
 Identities = 118/259 (45%), Positives = 156/259 (60%), Gaps = 9/259 (3%)

Query: 37  PNLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLK 96
           P++ +   GTGGRSSF+GI  TVFG TGF+GRYV + + K G+++ILP R    D Q LK
Sbjct: 14  PSVTSDAVGTGGRSSFSGITCTVFGSTGFLGRYVVHHVAKSGSRMILPTRCSENDRQHLK 73

Query: 97  VCGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARI 156
           V GDLGQ++   Y + DEE+I  AV  SNVVIN+VGR++ET+NF + DV+V   +++A I
Sbjct: 74  VMGDLGQIVQLDYGIRDEETIRYAVERSNVVINMVGREWETRNFSFEDVNVTFPKKLAEI 133

Query: 157 CREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYG 216
           C + GV R +H+S L AEE         PSA+  SK  GE AVRE +P+ATI+R + I G
Sbjct: 134 CADVGVRRLVHVSALGAEE-------DHPSAYYRSKAAGEAAVREAFPSATIVRPAKIVG 186

Query: 217 SEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAV 276
            EDRFL       R +   +P+   G  T  QPVFV DVA  I     D+ T    Y+  
Sbjct: 187 VEDRFLNIFGEHSRKYP-AVPIIDGG-DTKHQPVFVDDVAVAIRQIVHDELTSGRTYELA 244

Query: 277 GPKRYLLADLVDWFYKLMR 295
           G K Y   +L     K +R
Sbjct: 245 GNKVYTFDELAKMVLKTIR 263


>UniRef50_Q4PHN2 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 392

 Score =  194 bits (472), Expect = 5e-48
 Identities = 122/289 (42%), Positives = 165/289 (57%), Gaps = 19/289 (6%)

Query: 2   AAIALKTQATSKLLHLNGSMSVVYIKAANYSSDRKPNLAAYKRGT--GGRSSFNGIVATV 59
           A+ AL+ +A S LL   GS  V      + + +RK      K G   GGRSS +G V TV
Sbjct: 13  ASSALRFEARSSLLR--GSQVVQARNVHDLTINRKTGKPIIKSGPYGGGRSSVSGHVVTV 70

Query: 60  FGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAK 119
           FGCTGF+GRYV N+L + G+Q+I+PYR D  + + LKV GDLGQV+   + L  +E I +
Sbjct: 71  FGCTGFLGRYVVNRLAQKGSQVIVPYR-DEDEKRHLKVMGDLGQVVPMEWDLRHDEQIEE 129

Query: 120 AVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKP 179
            VR+S+VV NL GR YETKNF +NDVHV G +RIA+I    GV RFIH+S+LNA+ +   
Sbjct: 130 CVRHSDVVYNLTGRHYETKNFTFNDVHVTGAQRIAQIAEASGVGRFIHVSHLNADAN--- 186

Query: 180 LVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLY 239
                PSA+  SK  GE  V+  +  ATI+R   ++G EDRFL    N+M  +     + 
Sbjct: 187 ----SPSAFLRSKAEGEAVVKRAFEGATIVRPGTMWGHEDRFL----NQMAVYPYAWRV- 237

Query: 240 KNGLATVKQPVFVSDVAQGIVNAARDDDTKC-EVYQAVGPKRYLLADLV 287
            N   T  +PV   DVA  +      D T     +   GPK Y +  ++
Sbjct: 238 -NQGQTKMRPVHSLDVAHALEKMLEADVTSMGATFSLAGPKEYTIGQIL 285


>UniRef50_A7Q1K0 Cluster: Chromosome chr7 scaffold_44, whole genome
           shotgun sequence; n=6; Magnoliophyta|Rep: Chromosome
           chr7 scaffold_44, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 399

 Score =  193 bits (471), Expect = 6e-48
 Identities = 119/321 (37%), Positives = 181/321 (56%), Gaps = 16/321 (4%)

Query: 43  KRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLG 102
           ++GTGGRSS +GIVA VFG TGF+GRYV  +L K+G+Q+++P+RG     + LK+ GDLG
Sbjct: 54  RKGTGGRSSVSGIVAVVFGATGFLGRYVVQQLAKMGSQVLVPFRGSEDSHRHLKLMGDLG 113

Query: 103 QVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREE-G 161
           Q++   Y+  DE SI   +  +NVV+NL+GR+YET+N+ + +V+     ++A I +E  G
Sbjct: 114 QIVPMKYNPRDENSIKAVMAKANVVLNLIGREYETRNYSFEEVNHHMAEQLAMISKEHGG 173

Query: 162 VERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRF 221
           + RFI +S L A           PS   ++K   E AV  E P ATI+R + + G+EDR 
Sbjct: 174 IMRFIQVSCLGASP-------SSPSRMLMAKAAAEEAVLRELPEATIMRPAVMIGTEDRI 226

Query: 222 LRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKC-EVYQAVGPKR 280
           L       + +   +PLY +G +T  QPV+V DVA  I+ A +DD T   +VY+  GP+ 
Sbjct: 227 LNRWAQFAKKY-GFLPLYGDG-STKFQPVYVIDVAAAIMAALKDDGTSMGKVYELGGPEI 284

Query: 281 YLLADLVDWFYKLMRKDEKWGGYIRYDMKYDPILPL-KVALVNAISPAYPLGNLHWEGIE 339
           + + +L    Y  +R   +W  Y++        + L +  L+N +    P   L    + 
Sbjct: 285 FTMHELAAVMYDTIR---EWPRYVKVPFPIAKAMTLPREILLNKVPFPLPTPGLFNLDLI 341

Query: 340 REATSDNVVI-GVPTLEDLGV 359
              TSD VV     T +DLG+
Sbjct: 342 NAFTSDTVVSENALTFDDLGI 362


>UniRef50_P25284 Cluster: NADH-ubiquinone oxidoreductase 40 kDa
           subunit, mitochondrial precursor; n=17;
           Pezizomycotina|Rep: NADH-ubiquinone oxidoreductase 40
           kDa subunit, mitochondrial precursor - Neurospora crassa
          Length = 375

 Score =  191 bits (465), Expect = 3e-47
 Identities = 118/338 (34%), Positives = 187/338 (55%), Gaps = 23/338 (6%)

Query: 44  RGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQ 103
           R  GGRSS  G  ATVFG TG +GRY+ N+L + G  +++P+R D Y+ + LKV GDLG+
Sbjct: 41  RNQGGRSSLGGHTATVFGATGQLGRYIVNRLARQGCTVVIPFR-DEYNKRHLKVTGDLGK 99

Query: 104 VLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVE 163
           V+   + L + +SI ++VR+S+VV NL+GRDY TKNF + DVH++G  RIA    +  V+
Sbjct: 100 VVMIEFDLRNTQSIEESVRHSDVVYNLIGRDYPTKNFSFEDVHIEGAERIAEAVAKYDVD 159

Query: 164 RFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLR 223
           RFIH+S  NA+ + +         +  +K  GE  VR  +P  TI+R + ++G EDR   
Sbjct: 160 RFIHVSSYNADPNSE-------CEFFATKARGEQVVRSIFPETTIVRPAPMFGFEDR--- 209

Query: 224 SLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLL 283
            L++K+ S  N+  L  NG+     PV V DV Q +     DD+T  E ++  GPK Y  
Sbjct: 210 -LLHKLASVKNI--LTSNGMQEKYNPVHVIDVGQALEQMLWDDNTASETFELYGPKTYTT 266

Query: 284 ADLVDWFYKLMRKDEKWGGYIRYDMKYDPILPLKVALVNAISPAYPLGNLHWEGIEREAT 343
           A++ +   + + K  +   ++    K   + P+   L  A+   +P+  +  + IERE  
Sbjct: 267 AEISEMVDREIYKRRR---HVNVPKKI--LKPIAGVLNKAL--WWPI--MSADEIEREFH 317

Query: 344 SDNVVIGVPTLEDLGVTLTHMEDQVPWELKPFRAHQYY 381
              +     T +DLG+    + +     L+ +R++ YY
Sbjct: 318 DQVIDPEAKTFKDLGIEPADIANFTYHYLQSYRSNAYY 355


>UniRef50_Q6C7X4 Cluster: Similar to tr|Q86ZJ8 Podospora anserina;
           n=1; Yarrowia lipolytica|Rep: Similar to tr|Q86ZJ8
           Podospora anserina - Yarrowia lipolytica (Candida
           lipolytica)
          Length = 375

 Score =  190 bits (462), Expect = 7e-47
 Identities = 117/341 (34%), Positives = 181/341 (53%), Gaps = 25/341 (7%)

Query: 44  RGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQ 103
           +GTGGRSS  G  ATVFG  GF+G Y+  KL K GT +++PYR +    + LKV GDLG 
Sbjct: 43  KGTGGRSSRTGYTATVFGANGFLGSYLTAKLAKHGTTVVVPYREEMAK-RHLKVTGDLGV 101

Query: 104 VLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVE 163
           V F    L + ESI +AVR+S++V+NL+GR+YETKNF Y DVHV+G RRIA   ++  + 
Sbjct: 102 VNFLEMDLRNLESIDEAVRHSDIVVNLIGREYETKNFNYYDVHVEGARRIAEAVKKHNIA 161

Query: 164 RFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLR 223
           R+IH+S  NAE       +  PS +  +K LGE   ++  P ATI+R + ++G ED++  
Sbjct: 162 RYIHVSAFNAE-------IDSPSEFNHTKGLGEQVTKDIVPWATIVRPAPMFGREDKW-- 212

Query: 224 SLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLL 283
             +++M     L+    N       PV V DVA  +     DD T  + ++  GP+++  
Sbjct: 213 -FLDRMARSPCLVS--ANKFQETSNPVHVIDVAAALERICFDDSTVAQTFELYGPQKFTQ 269

Query: 284 ADLVDWFYKLMRKDEKWGGYIRYDMKYDPILPLKVALVNAI-SPAYPLGNLHWEGIEREA 342
             ++D   + +RK+      +R+      +         AI  P Y       + +ER+ 
Sbjct: 270 KQIIDMVSETLRKE------VRHIELPKALYQAYTKATQAIWWPTYSP-----DQVERQF 318

Query: 343 TSDNVVIGVPTLEDLGVTLTHMEDQVPWELKPFRAHQYYMD 383
            S  +     T  DL +T   + D +   ++P+R + +  D
Sbjct: 319 LSQKIDPSAKTFNDLDLTPMELPDLMFKLIRPYRVNTFQHD 359


>UniRef50_A2QSH0 Cluster: Catalytic activity: NADH + ubiquinone =
           NAD+ + ubiquinol; n=4; Pezizomycotina|Rep: Catalytic
           activity: NADH + ubiquinone = NAD+ + ubiquinol -
           Aspergillus niger
          Length = 372

 Score =  181 bits (441), Expect = 3e-44
 Identities = 103/242 (42%), Positives = 138/242 (57%), Gaps = 14/242 (5%)

Query: 47  GGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLF 106
           GGRSS  G  ATVFG TGF+GRY+ NKL   G  +++PYR +    + LKV GDLG+V F
Sbjct: 38  GGRSSLGGHTATVFGATGFLGRYIVNKLATQGCTVVVPYREEM-TKRHLKVTGDLGRVNF 96

Query: 107 TPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFI 166
             Y L + +SI +AVR+S+VV NLVGR Y TKNF Y DVHVDG  RI     +  V+RFI
Sbjct: 97  IEYDLRNTQSIEEAVRHSDVVYNLVGRQYPTKNFSYTDVHVDGTERIVEAVAKYDVDRFI 156

Query: 167 HLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLV 226
           H+S  NA           PS +  +K  GE  VR  YP  TI+R + ++G ED    +L+
Sbjct: 157 HVSSYNASR-------DSPSEYFATKAWGEEIVRNIYPETTIVRPAPMFGFED----NLL 205

Query: 227 NKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADL 286
           +K+   +NL  L  N +     PV   DV   +     DD T  + ++  GPK Y  A++
Sbjct: 206 HKLARVTNL--LTSNHMQERYWPVHAIDVGTALERMLHDDSTVGQTFELYGPKNYSTAEI 263

Query: 287 VD 288
            +
Sbjct: 264 AE 265


>UniRef50_Q6V506 Cluster: Putative NADH:ubiquinone oxidoreductase 39
           kDa subunit; n=1; Chlamydomonas reinhardtii|Rep:
           Putative NADH:ubiquinone oxidoreductase 39 kDa subunit -
           Chlamydomonas reinhardtii
          Length = 397

 Score =  174 bits (423), Expect = 4e-42
 Identities = 109/299 (36%), Positives = 167/299 (55%), Gaps = 16/299 (5%)

Query: 1   MAAIALKTQATSKLLHLNGSMSVVYIKAANYSS-DRKPNL-AAYKRGTGGRSSFNGIVAT 58
           M  I  +  A S L  L G   + +  AA+ SS D    L  A K G GGRSS +GI AT
Sbjct: 1   MLPILGRNAAGSALARLAG---LRWAAAASQSSRDYSSTLMTADKLGPGGRSSVSGITAT 57

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTP-YHLLDEESI 117
           VFG  GF+G Y+ N+L K G+Q++ P+R    +A  LK  GDLGQ++  P   + +++ I
Sbjct: 58  VFGANGFLGSYIVNELAKRGSQVVCPFRSTENEAMHLKQMGDLGQIVLLPELDIRNDDDI 117

Query: 118 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEG-VERFIHLSYLNAEEH 176
            +A+  SNV+IN VG   +TKN+ + DVHVD  +R+A++  E G V+R IH S + A+E+
Sbjct: 118 KRAISRSNVIINCVGMRLQTKNWSFEDVHVDFPKRLAKLAAETGQVQRLIHFSDMGADEN 177

Query: 177 PKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLM 236
            K L ++       +K +G+  V + +P ATI+R  DI G ED F   L+ ++ + +   
Sbjct: 178 HKSLRMR-------TKAVGDKEVLDAFPDATIVRPGDIVGIEDHFYNYLIYQL-TLTVFA 229

Query: 237 PLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMR 295
           P+ ++G   + QP +V DVA  +    R  DT  +     GP+   + ++ D   K +R
Sbjct: 230 PVVESGSNKI-QPTYVLDVADAVAALLRKPDTAGKTLYLGGPEVLTMREVYDLLLKTLR 287


>UniRef50_Q559Z0 Cluster: Putative uncharacterized protein; n=2;
           Dictyostelium discoideum|Rep: Putative uncharacterized
           protein - Dictyostelium discoideum AX4
          Length = 356

 Score =  165 bits (401), Expect = 2e-39
 Identities = 104/335 (31%), Positives = 172/335 (51%), Gaps = 19/335 (5%)

Query: 47  GGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLF 106
           G R+   G+VATVFG TGF GRY+   L + G Q+++PYR +    + LKV G+LGQ++ 
Sbjct: 32  GSRTQTTGLVATVFGATGFTGRYLVQLLARTGIQVVVPYRCEDEGFRDLKVLGELGQIIP 91

Query: 107 TPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFI 166
             + + D ESI +A+ +SN+VIN+ GRDYET+NF  +D++V    RIA +   + VE++I
Sbjct: 92  VRFDIRDSESIERAISHSNIVINMAGRDYETRNFSLDDINVHAASRIADL--SKNVEKYI 149

Query: 167 HLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLV 226
           H+S L A E         PS +  SK +GE   RE  P  T++R S I+G ED+F+    
Sbjct: 150 HVSTLRASE-------DSPSHFSRSKAIGEKLTREIIPNCTVVRPSIIFGDEDKFINKW- 201

Query: 227 NKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADL 286
           +K+  +   +P Y        QP+   D+A GI++      T  +VY+  G + +   + 
Sbjct: 202 SKVSQNWPFIPRYNQQHKI--QPLHCYDLASGILSILETPGTSGKVYEFAGDEVFTWDEF 259

Query: 287 VDWFYKLMRKDEKWGGYIRYDMKYDPILPLKVALVNAISPAYPLGNLHWEGIEREATSDN 346
           +D       +  K    +  D        +K    + +       N   + I+       
Sbjct: 260 LDMIIDGTAQYSKLNIPVSNDF-------MKFISEHLLERFARNPNFIKDQIDYHNQDMT 312

Query: 347 VVIGVPTLEDLGVTLTHMEDQVPWELKPFRAHQYY 381
             +G  TL+DL VT T +++++    + +R  +++
Sbjct: 313 TTVGALTLKDLNVTTTPIQEKLIRLSRMYRPGKFF 347


>UniRef50_Q5KJ08 Cluster: NADH dehydrogenase (Ubiquinone), putative;
           n=1; Filobasidiella neoformans|Rep: NADH dehydrogenase
           (Ubiquinone), putative - Cryptococcus neoformans
           (Filobasidiella neoformans)
          Length = 411

 Score =  164 bits (399), Expect = 3e-39
 Identities = 105/259 (40%), Positives = 151/259 (58%), Gaps = 18/259 (6%)

Query: 30  NYSSDRKPNLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDF 89
           N S+  +P +  Y   TGGRSS +G   TVFG TGF+ RY+  KL + GTQ+I+PYR D 
Sbjct: 37  NPSASVRPAIR-YGPPTGGRSSDSGRTVTVFGSTGFLARYLIQKLARQGTQVIVPYR-DE 94

Query: 90  YDAQRLKVCGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDG 149
            + +RL+ CGDLGQ++   +     E  A+ V++++VV NLVGRDYET+N+ Y+DV+V  
Sbjct: 95  DEKRRLRPCGDLGQIVPLEWDARIPEQTAECVKHADVVYNLVGRDYETRNYSYDDVNVKV 154

Query: 150 VRRIARICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATII 209
            + IA I  +  + R IH+S++NA         + PS +  +KY GE AVR+ +P ATI+
Sbjct: 155 AQSIAEISADMNIPRLIHVSHINANP-------ESPSEFYRTKYAGERAVRDAFPEATIV 207

Query: 210 RASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDD--D 267
           R S ++G ED     L+N +  +  L  L  NG  T   PV V DVAQ + N   D    
Sbjct: 208 RPSQLFGHED----WLLNAIARYPILCKL-NNG-NTKLFPVHVVDVAQAL-NLMFDAPVT 260

Query: 268 TKCEVYQAVGPKRYLLADL 286
           +    +   GP+ Y  A+L
Sbjct: 261 STASTFVLPGPELYNYAEL 279


>UniRef50_Q5AJA9 Cluster: Potential mitochondrial Complex I, 40kd
           subunit; n=5; Saccharomycetales|Rep: Potential
           mitochondrial Complex I, 40kd subunit - Candida albicans
           (Yeast)
          Length = 386

 Score =  161 bits (391), Expect = 3e-38
 Identities = 113/349 (32%), Positives = 177/349 (50%), Gaps = 21/349 (6%)

Query: 30  NYSSDRKPNLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDF 89
           N + + K N+A    G GGRSS  G  ATVFG +GF+GRYV +KL + GT  I+P+R D 
Sbjct: 31  NITKNGKVNVAV---GAGGRSSRTGYTATVFGASGFLGRYVTSKLARHGTTTIVPFRDDM 87

Query: 90  YDAQRLKVCGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDG 149
              + LKV GDLG V F      + +SI  +V +S++VIN +G DY+TKNFK  DV++  
Sbjct: 88  -KKRFLKVTGDLGVVNFVEIDARNLQSIEDSVAHSDIVINCIGVDYDTKNFKMADVNIAL 146

Query: 150 VRRIARICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATII 209
             RIA   ++  V R+IH+S  NA+ + +       S +  +K + E  VR+  P  TI+
Sbjct: 147 AERIAEATKKANVPRYIHVSSYNADPNSE-------SVFYATKGIAEQVVRDIIPDTTIV 199

Query: 210 RASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTK 269
           R + +YG ED  L  L  K++  +       N  A    PV+V DVA+ +   A DD T 
Sbjct: 200 RPAPMYGREDSLLNYLGPKVKMWT------PNKNAKEVWPVYVLDVARALERIAYDDSTA 253

Query: 270 CEVYQAVGPKRYLLADLVDWFYKLMRKDEKWGGYIRYDMKYDPILPLKVALVNAISPA-Y 328
            + ++  GP++    ++ +  + +     + G +      Y   LPL   +        +
Sbjct: 254 GQTFELYGPEKVTFQEIRNMIHGITENYAQVGPWSYQFADYAIPLPLAKTIAKVQQLVWW 313

Query: 329 PLGNLHWEGIEREATSDNVVIGVPTLEDLGV-TLTHMEDQVPWELKPFR 376
            L N   + ++R   +  +     T  DLG+  LT + D +   +K +R
Sbjct: 314 KLTNP--DQVQRLVINQKIDPNAKTFHDLGIDDLTRLPDVLFSYVKQWR 360


>UniRef50_UPI00006CB9E4 Cluster: hypothetical protein
           TTHERM_00557760; n=1; Tetrahymena thermophila SB210|Rep:
           hypothetical protein TTHERM_00557760 - Tetrahymena
           thermophila SB210
          Length = 398

 Score =  136 bits (329), Expect = 1e-30
 Identities = 92/285 (32%), Positives = 144/285 (50%), Gaps = 20/285 (7%)

Query: 23  VVYIKAANYSSDRKPNLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLI 82
           ++ +    +S  R   L  Y  G   R S +GI AT+FG TGF+G Y+   LG IG+ +I
Sbjct: 49  LIQVIQKQFSQQRSTQLKFYDGGN--RQSISGIRATIFGATGFMGPYIGAALGYIGSDVI 106

Query: 83  LPYRGDF-YD--AQRLKVCGDLGQ-VLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETK 138
            P+   + YD   + LK+C   GQ  +   ++  D+     A++ SNVVINLVG   + K
Sbjct: 107 FPHNHVYAYDDYVKELKLCAGSGQSYIMRHFNYDDDNMYDMAIKNSNVVINLVGSRLQNK 166

Query: 139 NFK---YNDVHVDGVRRIARIC-REEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYL 194
           NF+   Y ++HV   ++IA  C R   V R IH S   A+        K PS    +K+ 
Sbjct: 167 NFQKAAYANIHV--AKKIAEACARNPNVRRLIHFSAAGAD-------TKSPSPDLHTKFH 217

Query: 195 GECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSD 254
           GE AV   +P ATI R   +YG +D F+R  + K R       +  +     +QP+ ++D
Sbjct: 218 GEEAVLNAFPNATIFRPCTVYGMQDYFIRHWI-KERDWWYHFNIVTDDCTAKRQPILIND 276

Query: 255 VAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMRKDEK 299
           VAQ ++NA +  ++  ++Y+  GP  Y   ++ +    L  +  K
Sbjct: 277 VAQCVLNALKLQESAGQIYELGGPHVYSRLEVFEMLANLSGRPPK 321


>UniRef50_A7HPI7 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Parvibaculum lavamentivorans DS-1|Rep: NAD-dependent
           epimerase/dehydratase - Parvibaculum lavamentivorans
           DS-1
          Length = 321

 Score =  115 bits (277), Expect = 2e-24
 Identities = 78/231 (33%), Positives = 119/231 (51%), Gaps = 10/231 (4%)

Query: 58  TVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 117
           TVFG +GFVGR++   L K G ++ +  R    +A  L+  G +GQV     ++ D+ S+
Sbjct: 8   TVFGGSGFVGRHIVQTLAKRGYRIRVAVRRP-NEALFLRPMGVVGQVEPIQANIRDDASV 66

Query: 118 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 177
             AV  ++ V+NLVG  +ET    ++ V  +G  R+AR   E G  R IH+S + A+E  
Sbjct: 67  RAAVAGADAVVNLVGILHETGKQTFDAVQAEGAGRVARAAAEAGCGRLIHISAIGADE-- 124

Query: 178 KPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMP 237
                +  S +  +K LGE AVR+  P A I+R S ++G  D F        R    L P
Sbjct: 125 -----ESASHYGRTKALGEKAVRDAMPDAAIVRPSIVFGPGDSFFNRFAALARLFPAL-P 178

Query: 238 LYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVD 288
           L   G   + QPV+V DVA+G+V     +     VY+  GP+     +L++
Sbjct: 179 LIGGGTMRL-QPVYVKDVAEGVVQILEGEGLSGRVYEFGGPEVLTFRELME 228


>UniRef50_Q1GR77 Cluster: 3-beta hydroxysteroid
           dehydrogenase/isomerase; n=4; Sphingomonadaceae|Rep:
           3-beta hydroxysteroid dehydrogenase/isomerase -
           Sphingopyxis alaskensis (Sphingomonas alaskensis)
          Length = 312

 Score =  114 bits (274), Expect = 4e-24
 Identities = 101/329 (30%), Positives = 151/329 (45%), Gaps = 29/329 (8%)

Query: 51  SFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYH 110
           +F+G + TV G  GF+GRYV  +L   G ++ +  R D   A  LK  G LGQ  F    
Sbjct: 3   TFDGQLITVLGGGGFLGRYVVQRLLARGARVRIAQR-DPRAATFLKPLGGLGQTQFVHAD 61

Query: 111 LLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSY 170
           + D  S+A+AV+ S+ VINLVG   + +      V  DG   +A   +  G    +H+S 
Sbjct: 62  VRDAASVARAVQGSDAVINLVGAFDDMRA-----VQADGAGHVATTAKAAGARALVHVSA 116

Query: 171 LNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMR 230
           + A+          PSA+  SK  GE AVR  +  A I+R S I+G EDRF+      MR
Sbjct: 117 IGADRD-------SPSAYGRSKGDGEAAVRAAFTGAAILRPSIIFGREDRFINRFAGMMR 169

Query: 231 SHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWF 290
             + +MP+         QPV+V DVA  +V A  D  T   +++  GP+   + +L+ W 
Sbjct: 170 L-APVMPVI--APQAKFQPVYVGDVADAVVAALADTATG-RLFELGGPQVLTMRELLRWI 225

Query: 291 YKLMRKDEKWGGYIRYDMKYDPILPLKVALVNAISPAYPLGNLHWEGIEREATSDNVVI- 349
                +   +       +     L   +A     +P  P+    W  ++    SDNVV  
Sbjct: 226 ADATGRSPLF-------IDVPDFLASALATGFGWAPGAPITRDQWLMLQ----SDNVVAS 274

Query: 350 GVPTLEDLGVTLTHMEDQVPWELKPFRAH 378
           G   L +LG+T T +       L  +R H
Sbjct: 275 GAAGLAELGITPTPLAAVADGWLVQYRRH 303


>UniRef50_Q2GE21 Cluster: NADH-ubiquinone oxidoreductase family
           protein; n=1; Neorickettsia sennetsu str. Miyayama|Rep:
           NADH-ubiquinone oxidoreductase family protein -
           Neorickettsia sennetsu (strain Miyayama)
          Length = 340

 Score =  113 bits (273), Expect = 6e-24
 Identities = 78/238 (32%), Positives = 122/238 (51%), Gaps = 13/238 (5%)

Query: 58  TVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 117
           TVFG +GF+G YV  +L K G ++ +        A++LK+ G+LGQ+      +   + I
Sbjct: 34  TVFGGSGFIGSYVVRELVKSGYRVTV-VANSLSCAKKLKLSGNLGQISVVHGDIRYPDDI 92

Query: 118 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 177
            K +  S +VIN+VG   ET +  +  ++     ++A+I  E GV RFIH S L      
Sbjct: 93  VKGIGNSEIVINMVGVLRETSSASFGAINHLACAQVAQIAAENGVRRFIHFSAL------ 146

Query: 178 KPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRS-HSNLM 236
             L     + +  SK  GE AVR  +P + IIR   ++G ED F+   V   R     L+
Sbjct: 147 --LGCNGATKYGKSKLNGEEAVRSAFPESIIIRPGVVFGEEDNFINLFVKLGRKLRILLL 204

Query: 237 PLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLM 294
           P  K   A++ QPV+V D+A  +    +++  K E+Y  VG KRY L ++     +L+
Sbjct: 205 PACKT--ASI-QPVYVGDLALLVAKILQNETLKGEIYPVVGSKRYTLNEICSLISRLL 259


>UniRef50_Q3YT69 Cluster: NADH-ubiquinone oxidoreductase, putativ;
           n=8; Rickettsiales|Rep: NADH-ubiquinone oxidoreductase,
           putativ - Ehrlichia canis (strain Jake)
          Length = 320

 Score =  112 bits (270), Expect = 1e-23
 Identities = 69/238 (28%), Positives = 124/238 (52%), Gaps = 11/238 (4%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           +FG +GF+GRY+     + G  +I  +      A++LK+CG+LGQ+      + + + I 
Sbjct: 8   IFGGSGFIGRYLVKYFAENG-YIIKIFTRYPEKAKQLKLCGNLGQIEVISGDVTNVQEIE 66

Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 178
             +   +VV+NL+G  Y TKN  + D+H      IA+  +   VE  +H S +  +E   
Sbjct: 67  NNIFGCHVVVNLLGTLYSTKNSTFYDIHAKAAENIAKAAKSCDVELMVHFSAMGIDE--- 123

Query: 179 PLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPL 238
                + S +  SK +GE  V+  +P A IIR + ++G+EDRF      K+   S  +P+
Sbjct: 124 ----VQQSHYARSKLIGENLVKLAFPNAVIIRPNLVFGAEDRFFNKFA-KLTMISPFLPV 178

Query: 239 YKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMRK 296
              G A V QP++V D+A+ +     +  T  ++Y   GP+ Y   +L+++   ++++
Sbjct: 179 IGGGRA-VFQPIYVDDLAKFVFYIVNNAVTD-KLYNVCGPRTYSFKELLNFILSIIKR 234


>UniRef50_A4GHP1 Cluster: NADH-ubiquinone oxidoreductase; n=2;
           Bacteria|Rep: NADH-ubiquinone oxidoreductase -
           uncultured marine bacterium EB0_39F01
          Length = 330

 Score =  112 bits (269), Expect = 2e-23
 Identities = 77/241 (31%), Positives = 125/241 (51%), Gaps = 12/241 (4%)

Query: 56  VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 115
           + T+FG +GFVGRYV  ++ K G ++ +  R    +A  +K  GD+GQV     ++ DE+
Sbjct: 7   LVTIFGGSGFVGRYVAQRMAKEGWRVRVAVRRP-NEALFVKTYGDVGQVEPILANIRDEK 65

Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 175
           S   A+  ++ V+N VG   ET   K+ D+   G  +IA++  E GV+ F+H S + A+ 
Sbjct: 66  STRAAIIGADAVVNCVGILNETSKQKFTDLQSKGASQIAKLATECGVKTFVHFSAIGADI 125

Query: 176 HPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNL 235
           +     LK       SK  GE  V+  +  A I+R S ++G+ED+F       M   S L
Sbjct: 126 NSHSKYLK-------SKAEGEEMVKASFKNAVILRPSIVFGAEDQFFNRFAT-MAKLSPL 177

Query: 236 MPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMR 295
           +PL   G  T  QPV+V D+A+  V      + K  +Y+  GP+     +L+     ++R
Sbjct: 178 IPLV--GGETKFQPVYVDDIAKAAVKGVL-GEAKRGIYELGGPQAASFKELIIMLMGIIR 234

Query: 296 K 296
           +
Sbjct: 235 R 235


>UniRef50_A4WW99 Cluster: NADH dehydrogenase; n=5;
           Rhodobacterales|Rep: NADH dehydrogenase - Rhodobacter
           sphaeroides ATCC 17025
          Length = 328

 Score =  111 bits (266), Expect = 4e-23
 Identities = 93/327 (28%), Positives = 150/327 (45%), Gaps = 16/327 (4%)

Query: 56  VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 115
           + T++G +GFVGRY+  ++ + G ++ +  R    +A  +K  G +GQV     ++ D+ 
Sbjct: 4   LVTIYGGSGFVGRYIARRMAQQGWRVRVAVRRP-NEALFVKPYGVVGQVEPVFCNIRDDA 62

Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 175
           S+   +  ++ V+N VG   E    ++  V  +G  R+AR+   EGV+  + +S + A+ 
Sbjct: 63  SVRAVMHGADAVVNCVGILAEAGKNRFQSVQAEGAARVARLAAAEGVQALVQISAIGAD- 121

Query: 176 HPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNL 235
                    PSA+  SK  GE AV + +P A I+R S I+G ED F      +M   S +
Sbjct: 122 ------ADSPSAYARSKAAGEAAVLQAFPRAVILRPSVIFGPEDDFFNRFA-RMARFSPV 174

Query: 236 MPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMR 295
           +P+   G  T  QPVFV DVAQ  V A         +Y+  GP       L+     L+R
Sbjct: 175 LPVV--GGETRFQPVFVDDVAQAAV-AGVLGRAAPGIYELGGPDAESFRALMQ---MLLR 228

Query: 296 KDEKWGGYIRYDMKYDPILPLKVALVNAISPAYPLGNLHWEGIEREATSDNVVI-GVPTL 354
             E+    +        ++   + L+  ++              R    DNVV  G   L
Sbjct: 229 VIERRKMIVNVPFGVARLMAATLDLLQTVTLGLLANKTLTRDQVRNLARDNVVSPGARGL 288

Query: 355 EDLGVTLTHMEDQVPWELKPFRAHQYY 381
            DLG++ T ME  +P  L  +R    Y
Sbjct: 289 ADLGISPTAMEAVLPEYLWSYRPSGQY 315


>UniRef50_A0BZW4 Cluster: Chromosome undetermined scaffold_14, whole
           genome shotgun sequence; n=4; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_14,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 351

 Score =  110 bits (265), Expect = 5e-23
 Identities = 83/273 (30%), Positives = 136/273 (49%), Gaps = 21/273 (7%)

Query: 36  KPNLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDF-YD--A 92
           +P L  + +G   + + +GI AT+ G T F G Y+   LG IG++LI P+   + Y+   
Sbjct: 14  RPKLHIFDKGA--KHTPSGIRATIHGGTSFSGIYMGGMLGNIGSELIFPHNHQYNYEDHV 71

Query: 93  QRLKVCGDLGQV-LFTPYHLLDEESIAKAVRYSNVVINLVG---RDYETKNFKYNDVHVD 148
           + LK     GQ  L    +  ++E I   ++ SNVV+NL+G      + K F+ + +   
Sbjct: 72  RELKTTSGPGQNWLLHDMNYDNKEMIEWTMKNSNVVVNLLGPQKTSEKQKGFRVDQLSQC 131

Query: 149 GVRRIARICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATI 208
              ++    +  GV R IH S   A  H + L L+       +KY+GE  V   +P ATI
Sbjct: 132 QKEQLKHALKTPGVIRLIHFSACGANPHAESLDLQ-------TKYIGEQEVLNAFPNATI 184

Query: 209 IRASDIYGSEDRFLRSL-VNKMRSHS-NLMPLYKNGLATVKQPVFVSDVAQGIVNAARDD 266
            R S + G  D F     V K   H+ N++P   +     +QP+FV DVAQ ++NA +  
Sbjct: 185 FRPSVMVGDNDDFAYHWQVQKRYFHNFNIVP---DNCQAKRQPIFVQDVAQAMLNALKMP 241

Query: 267 DTKCEVYQAVGPKRYLLADLVDWFYKLMRKDEK 299
           +T  + Y+  GP  Y L +  + F+ ++++  K
Sbjct: 242 ETIGQTYELGGPHVYTLLECYEMFHNIVQRPPK 274


>UniRef50_Q3JEV6 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Nitrosococcus oceani ATCC 19707|Rep: NAD-dependent
           epimerase/dehydratase - Nitrosococcus oceani (strain
           ATCC 19707 / NCIMB 11848)
          Length = 308

 Score =  109 bits (263), Expect = 1e-22
 Identities = 69/231 (29%), Positives = 120/231 (51%), Gaps = 14/231 (6%)

Query: 58  TVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 117
           TVFG TGF+GR + ++L + G ++ +  R      +   + G  GQ+      + DE+S+
Sbjct: 13  TVFGGTGFLGRAIVHRLVESGMRVRIVAR----HPRAPNLAGARGQIALQRADVRDEDSV 68

Query: 118 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 177
           A+A++ +  V+N VG   E     +  +H +G  R+AR   E G+ R IH+S +  +   
Sbjct: 69  AEALKGATGVVNAVGLYVEQGQATFRAIHEEGAERVARRAGEAGIRRLIHISGIGVDP-- 126

Query: 178 KPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMP 237
                   S +  ++  GE  VRE +P ATI+R S ++G  D FL SL  K  +   ++P
Sbjct: 127 -----ASASKYARARAYGEQRVREIFPNATILRPSVMFGPNDAFLNSL--KTVTRLPVVP 179

Query: 238 LYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVD 288
           L+  G +T  QPV+V DVA+ ++      +   + ++  G + Y   D+++
Sbjct: 180 LFGQG-STRLQPVYVEDVARAVLQVLEMPEASGKTFELGGARAYRYRDIIE 229


>UniRef50_Q0BUA2 Cluster: NADH-ubiquinone oxidoreductase 39-40 kDa
           subunit-like protein; n=2; Acetobacteraceae|Rep:
           NADH-ubiquinone oxidoreductase 39-40 kDa subunit-like
           protein - Granulobacter bethesdensis (strain ATCC
           BAA-1260 / CGDNIH1)
          Length = 333

 Score =  109 bits (261), Expect = 2e-22
 Identities = 103/333 (30%), Positives = 158/333 (47%), Gaps = 28/333 (8%)

Query: 49  RSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTP 108
           +S+  G +ATVFG +GF+G+ +   L + G Q+ +P R D     +LK  G +GQ++   
Sbjct: 11  QSTMAGRIATVFGGSGFLGQSLIRLLAREGYQVRVPVR-DPEQVLKLKSAGSVGQIVPLG 69

Query: 109 YHLLD---EESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERF 165
             L     E  IA+AV+ +++V+NLVG   E +   +  VHV     IA +  + GV  F
Sbjct: 70  VSLGSRDAEAGIARAVQGASLVVNLVGLLAEARKGDFQRVHVQAAGLIASLSAQAGVLSF 129

Query: 166 IHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSL 225
           +H+S L A+          PSA+  SK  GE AVR   P A I+R S ++G+ED F    
Sbjct: 130 MHISALGADP-------ASPSAYGRSKAEGEEAVRSAVPQAAILRPSVVFGAEDHFFNRF 182

Query: 226 VNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLAD 285
                S   +  +Y N   +  QPV+V DVA+ I+ AA        V +  GP+   + D
Sbjct: 183 AAMAVSLPVVPVIYGN---SRMQPVYVEDVARAILAAA--TQAAGNVIELGGPEVLTMRD 237

Query: 286 LVDWFYKLMRKDEKWGGYIRYDMKYDPILPLKVALVNA-ISPAYPLGNLHWEGIEREATS 344
           +      ++ + +        D      +P KVA+  A I+   P   L  + +    + 
Sbjct: 238 IQHRILTMIGRKKP-----LID------IPDKVAMALAMIAEKMPGRPLTTDQLAMLGSG 286

Query: 345 DNVVIGVPTLEDLGVTLTHMEDQVPWELKPFRA 377
             V     TLE LG+  T ++  VP  L  FRA
Sbjct: 287 SVVSPQALTLETLGIVPTPIDLVVPHYLSRFRA 319


>UniRef50_Q2RYH4 Cluster: 3-beta-hydroxy-delta(5)-steroid
           dehydrogenase; n=3; Rhodospirillaceae|Rep:
           3-beta-hydroxy-delta(5)-steroid dehydrogenase -
           Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255)
          Length = 340

 Score =  107 bits (258), Expect = 4e-22
 Identities = 80/260 (30%), Positives = 130/260 (50%), Gaps = 26/260 (10%)

Query: 54  GIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLD 113
           G V TVFG +G +GR +   L   G ++ +  R D   A  LK  G LGQ+      + D
Sbjct: 3   GRVVTVFGGSGSIGRQLVALLADQGARVRVAVR-DTEKAHFLKPLGQLGQIAPISASVSD 61

Query: 114 EESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA 173
             S+ +AV  ++ V+NLVG   E+    +  VHVDG   +AR   E GV+  IH+S L A
Sbjct: 62  AASVKRAVEGADQVVNLVGILAESGRRTFQAVHVDGAATVARASAEAGVDALIHMSALGA 121

Query: 174 EEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHS 233
           +E          + +  +K LGE AVRE +P ATI+R S ++G +D F  +L   ++  S
Sbjct: 122 DE-------ASDANYSKTKALGEKAVREAFPAATILRPSVVFGPDDGFF-NLFAGLQRLS 173

Query: 234 NLMPLYK--------NGLATVK---------QPVFVSDVAQGIVNAARDDDTKCEVYQAV 276
            ++P +         +G+  +          QPV+V DVA+ ++        + + Y+  
Sbjct: 174 PVLPYFTRDGFRRGGSGVCGIDLAGSGGPKFQPVYVGDVARAMIAILDTPALRGKTYELG 233

Query: 277 GPKRYLLADLVDWFYKLMRK 296
           GP+ Y + +++D    + R+
Sbjct: 234 GPRVYSMKEIMDLVVAVTRR 253


>UniRef50_Q1GCR4 Cluster: 3-beta hydroxysteroid
           dehydrogenase/isomerase; n=17; Rhodobacterales|Rep:
           3-beta hydroxysteroid dehydrogenase/isomerase -
           Silicibacter sp. (strain TM1040)
          Length = 329

 Score =  107 bits (257), Expect = 5e-22
 Identities = 91/335 (27%), Positives = 153/335 (45%), Gaps = 19/335 (5%)

Query: 56  VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 115
           + T++G +GFVGRY+  ++ K G ++ +  R    +A  +K  G  GQV     ++ D+ 
Sbjct: 4   LVTIYGGSGFVGRYIARRMAKEGWRVRVAVRRP-NEAMHVKPYGVPGQVEPVFCNIRDDA 62

Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 175
           S+A  +  ++ V+N VG   E     ++ V  +G  RIARI  + GVER +H+S + A+ 
Sbjct: 63  SVAAVMAGADAVVNCVGVLNEVGKNTFSAVQSEGAGRIARIAADTGVERLVHVSAIGAD- 121

Query: 176 HPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNL 235
                     SA+  +K  GE AV E +P+A I+R S I+G ED+F     + M     +
Sbjct: 122 ------ADGDSAYARTKAEGEAAVLEAFPSAMILRPSIIFGPEDQFFNRFAS-MTRFGPV 174

Query: 236 MPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMR 295
           +P+   G  T  QPV+V DVA+  V A          Y+  GP+     +L+     ++ 
Sbjct: 175 LPI--AGGTTRFQPVYVDDVAKAAV-AGLTGQAAAGTYELGGPEVKSFTELMSQMLDVIH 231

Query: 296 KDEKWGGYIRYDMKYDPILPLKVALVNAISPAYPLGNLHWEGIEREATSDNVVI-GVPTL 354
           +         +  +   ++     +  A++       L      +   +DNVV  G   L
Sbjct: 232 RRRLVVSLPNFVAR---LMAFGFDMAQAVTFGLFTNGLLTRDQLKNLQNDNVVSEGAKGL 288

Query: 355 EDLGVTLTHMEDQVP---WELKPFRAHQYYMDRLG 386
            DLG+    M   +P   W+ +P   +   M   G
Sbjct: 289 ADLGIEPVTMGSVLPDYLWKFRPSGQYDELMKSAG 323


>UniRef50_Q38CX2 Cluster: Putative uncharacterized protein; n=5;
           Trypanosomatidae|Rep: Putative uncharacterized protein -
           Trypanosoma brucei
          Length = 373

 Score =  106 bits (254), Expect = 1e-21
 Identities = 79/259 (30%), Positives = 126/259 (48%), Gaps = 23/259 (8%)

Query: 44  RGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYR---GDFYDAQRLKVCGD 100
           RG G  ++  G+    FG TG +G ++ +     G   I+P+R   G     + L++ GD
Sbjct: 19  RGGGSEANAMGVNVATFGATGVLGTHIHHLCCYHGFTSIVPFRFRAGMASGVRHLRMAGD 78

Query: 101 --LGQVLFTPYHLLDEESIAKAVRYS-NVVINLVGR-----DYETKN--FKYNDVHVDGV 150
             +GQ   T Y + D+E + K++    + VIN VG       YE     F    ++V+  
Sbjct: 79  GTVGQNFDTDYEI-DKEFVVKSILEKVDNVINAVGAWQEPAVYENSQSWFSMEAINVEWP 137

Query: 151 RRIARICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIR 210
           R +AR CRE G+ R  H+S + A+ H    +L++  A        E AV EE+PTATIIR
Sbjct: 138 RMLARWCREMGILRLTHMSMVGADLHSPSKLLRQKRA-------AEIAVLEEFPTATIIR 190

Query: 211 ASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKC 270
            +DI+   D      +   R +  ++P+   G   + QPVF  D+A+    +   D T+ 
Sbjct: 191 GTDIFAENDYSYSRYLMAQRKY-KIVPMPNRG-QRIHQPVFAGDLAEATCRSILLDHTEG 248

Query: 271 EVYQAVGPKRYLLADLVDW 289
            + +  GP R+  AD + W
Sbjct: 249 RIAELGGPVRFTTADYLRW 267


>UniRef50_A7DMA8 Cluster: NAD-dependent epimerase/dehydratase; n=3;
           Alphaproteobacteria|Rep: NAD-dependent
           epimerase/dehydratase - Methylobacterium extorquens PA1
          Length = 389

 Score =  101 bits (243), Expect = 3e-20
 Identities = 104/341 (30%), Positives = 162/341 (47%), Gaps = 32/341 (9%)

Query: 56  VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 115
           + TVFG +GF+GR+V   L K G ++ +  R     A  L+  G +GQ++    +L   +
Sbjct: 18  LVTVFGGSGFLGRHVVRALAKRGYRIRVAVRRPDL-ALFLQPLGKVGQIVGVQANLRYPD 76

Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 175
           SI +AV +S++VINLVG   E+ + +++ +  +G   IAR     G  + +H+S L A+ 
Sbjct: 77  SIRRAVEHSDIVINLVGILQESGSQRFSKLQTEGAGEIARAAAAVGA-KLVHVSALGADP 135

Query: 176 HPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNL 235
                    PS +  SK LGE  V    P A I R S ++G  D F     N+  S +  
Sbjct: 136 -------DSPSLYARSKALGEAEVLRASPDAVIFRPSLVFGPGDGFF----NRFASLATF 184

Query: 236 MP-LYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLM 294
           +P L   G  T  QPVFV DVA+ I  A         VY+  GP+     + +++F + M
Sbjct: 185 LPALPLAGAQTRFQPVFVGDVAEAIARAVDGLAAGGRVYELGGPE----VNTLEYFVRYM 240

Query: 295 RKDEKWGGYIRYDMKYDPILPLKVALVNAISPAYPLGNLHWE-GIEREATS----DNVVI 349
            +       +  D+  +P+  L+  ++  I+    LG L     + R+  +    DNVV 
Sbjct: 241 LEVTMRRRAV-LDLP-EPVARLQARVIE-IADTLTLGLLPANLKLTRDQVALLQFDNVVS 297

Query: 350 GVP-----TLEDLGVTLTHMEDQVPWELKPFR-AHQYYMDR 384
                   T+E LG+  T +E  VP  L  FR A Q+   R
Sbjct: 298 DAAKAEGRTIEALGIVPTAVEAVVPGYLWRFRKAGQFAQGR 338


>UniRef50_Q98CD7 Cluster: NADH dehydrogenase (Ubiquinone) 1 alpha
           subcomplex; n=31; Alphaproteobacteria|Rep: NADH
           dehydrogenase (Ubiquinone) 1 alpha subcomplex -
           Rhizobium loti (Mesorhizobium loti)
          Length = 341

 Score = 97.5 bits (232), Expect = 5e-19
 Identities = 73/223 (32%), Positives = 112/223 (50%), Gaps = 11/223 (4%)

Query: 56  VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 115
           +  VFG +GFVGR+V   L K G ++ +  R     A  L+  G++GQ+     ++    
Sbjct: 26  LVVVFGGSGFVGRHVVRALAKRGYRIRVACRRPDL-AGHLQPLGNVGQIQPVQANVRVRW 84

Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 175
           S+ +AV+ ++ V+NLV   +ET   K++ VH  G R +A   R  G     H+S L A+ 
Sbjct: 85  SVDRAVQGADHVVNLVAILHETGRQKFSAVHEFGSRAVAEAARSVGA-GLTHISALGAD- 142

Query: 176 HPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNL 235
                 L   S +  +K LGE AV E  P A I R S  +G ED F     + M  +S +
Sbjct: 143 ------LDSESDYARTKALGEKAVLETIPDAVIFRPSINFGPEDSFFNRFAS-MARYSPV 195

Query: 236 MPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGP 278
           +PL   G  T  QPV+V DVA+ +  +      + ++Y+  GP
Sbjct: 196 LPLIGGG-QTKFQPVYVGDVAEAVARSVDGKIDRGQIYELGGP 237


>UniRef50_Q4FNB8 Cluster: Probable NADH-ubiquinone oxireductase;
           n=2; Candidatus Pelagibacter ubique|Rep: Probable
           NADH-ubiquinone oxireductase - Pelagibacter ubique
          Length = 322

 Score = 94.7 bits (225), Expect = 4e-18
 Identities = 65/239 (27%), Positives = 116/239 (48%), Gaps = 11/239 (4%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           +FG +G +GR++  KL K   ++ +  R        +K   + G +     ++ DE+ I 
Sbjct: 8   IFGGSGQIGRHLIRKLTKNNYKVTVVTRNLHQKGYAIKTQANAGYIDIVEANIFDEKKIR 67

Query: 119 KAVRYSNVVINLVGRDYET-KNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 177
           K    +++ INL+G  YE+ K   + ++H      ++++C+E  V++FIHLS L   + P
Sbjct: 68  KLFSQTDICINLIGILYESGKGNTFKNIHSIFPSILSKLCKEYKVQQFIHLSALGINDAP 127

Query: 178 KPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMP 237
                   S +  SK  GE  +++ +P ATI+R S +Y  +D F  S +  + S     P
Sbjct: 128 -------DSEYAKSKLDGELNIQKNFPLATILRPSVVYSVDDNFTTSFMT-LLSRLPFFP 179

Query: 238 LYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMRK 296
           LY NG +T   P+  SD+   I +         ++ + VGP    L +++     L+ K
Sbjct: 180 LYYNG-STKFAPIHCSDLTDTIYHVV-SKSIYSKIIECVGPDILSLKEILKKLLHLIDK 236


>UniRef50_Q2GII8 Cluster: NADH-ubiquinone oxidoreductase family
           protein; n=2; Anaplasma|Rep: NADH-ubiquinone
           oxidoreductase family protein - Anaplasma
           phagocytophilum (strain HZ)
          Length = 313

 Score = 93.5 bits (222), Expect = 9e-18
 Identities = 74/233 (31%), Positives = 110/233 (47%), Gaps = 20/233 (8%)

Query: 59  VFGCTGFVGRY-VCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 117
           VFG +GF+GRY VC  + +     +  Y  +   A RLK+ G LGQV      L D   I
Sbjct: 6   VFGGSGFIGRYLVCELVAR--KYSVTVYTRNHEKAARLKLFGRLGQVDIVCGKLSDAALI 63

Query: 118 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 177
            K +   +V++NLVG   + +      +HV     IA++  + G + F+H S + A+   
Sbjct: 64  QKLIADCDVIVNLVGTISDPRGAVLQYLHVTFPSNIAKLATKHG-KMFVHFSAMGAD--- 119

Query: 178 KPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMP 237
               + K S++  SK  GE  +R+    A I+R + ++G  D F     N  R  +  MP
Sbjct: 120 ----IAKTSSYAQSKLEGEKRIRDVCEDAVILRPNLVFGDGDNFFNKFANLARV-APFMP 174

Query: 238 LYKNGLATVKQPVFVSDVAQGIVNAARD---DDTKCEVYQAVGPKRYLLADLV 287
           L+  G   + QPV V DV    VN A D   +      Y+  GP  Y L DL+
Sbjct: 175 LFGGG-KNLLQPVHVDDV----VNVAMDLIVNQASSGTYEVAGPTVYSLKDLI 222


>UniRef50_Q0ACP9 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Alkalilimnicola ehrlichei MLHE-1|Rep: NAD-dependent
           epimerase/dehydratase - Alkalilimnicola ehrlichei
           (strain MLHE-1)
          Length = 320

 Score = 91.9 bits (218), Expect = 3e-17
 Identities = 71/235 (30%), Positives = 111/235 (47%), Gaps = 19/235 (8%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           + G +GF+G  +  +LG+ G ++I+P R      +R +    +  V     ++ DE+++ 
Sbjct: 8   ILGGSGFIGTTIAGRLGRDGHRVIVPTR----HRERSRHLLPVPNVEVVELNVNDEDALV 63

Query: 119 KAVRYSNVVINLVGRDYETKNFK---YNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 175
           +A +    VINLVG   E    K   +   HV+  RR+   C+  GV R++H+S L A+ 
Sbjct: 64  EAFQDCTAVINLVGILNELSGPKGEGFRRAHVELPRRVISACQRAGVGRYLHMSALGADP 123

Query: 176 HPKPLVLKKPSAWKISKYLGE---CAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSH 232
                  + PS ++ +K  GE    A   +  + T  R S ++GS D F       +R  
Sbjct: 124 -------EGPSLYQQTKGEGERLAIAAHGDGLSVTAFRPSVVFGSGDSFFNRFAGLLRLS 176

Query: 233 SNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287
              M L         QPV+V+DVA   +    D  T  +VY  VGPKRY L  LV
Sbjct: 177 PGFMFLPTPHAEF--QPVWVNDVASAFIRCLEDQATGGQVYDLVGPKRYTLEALV 229


>UniRef50_Q125I6 Cluster: NAD-dependent epimerase/dehydratase; n=3;
           Comamonadaceae|Rep: NAD-dependent epimerase/dehydratase
           - Polaromonas sp. (strain JS666 / ATCC BAA-500)
          Length = 318

 Score = 90.2 bits (214), Expect = 8e-17
 Identities = 84/304 (27%), Positives = 142/304 (46%), Gaps = 24/304 (7%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           + G TGFVGR+VC KL ++  ++ +  R    +A+ L+    L  V+    H  D  ++ 
Sbjct: 6   ILGGTGFVGRHVCEKLAQLQCRVTVATRR-LDNARHLQTLPML-DVIEIDVH--DSAALT 61

Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 178
             +   + V+NL+   + T+   +   HV     + R C   G+ R +H+S L A     
Sbjct: 62  SLLAGHDAVVNLIAILHGTEA-AFEKAHVQLPLALVRACEAAGLRRIVHISALGAS---- 116

Query: 179 PLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPL 238
              +   S ++ SK  GE  +       T++R S I+G+ED+FL +     +    L P+
Sbjct: 117 ---VSSASMYQRSKARGEAVLLSAGLDVTLLRPSVIFGAEDKFLNTFARLQQ----LFPV 169

Query: 239 YKNGLATVK-QPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMRKD 297
                +  + QPV+V DVA  +V+  +D  +  +VY+A GP  + L  LV+   +    +
Sbjct: 170 VPLAASQARFQPVWVEDVASAVVHCLQDSSSIGQVYEACGPDVFTLRQLVELAGRYAGVN 229

Query: 298 EKWGGYIRYDMKYDPILPLKVALVNAISPAYPLGNLHWEGIEREATSDNVVIG-VPTLED 356
              GG  R  +     L    A +  + P  PL  L  + ++   T DNV  G +P L+ 
Sbjct: 230 ---GGKGRPVIALPAPLGRLQARLMELLPGEPL--LSRDNLDAMQT-DNVASGKLPGLKA 283

Query: 357 LGVT 360
           LG+T
Sbjct: 284 LGIT 287


>UniRef50_Q1GZ10 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Methylobacillus flagellatus KT|Rep: NAD-dependent
           epimerase/dehydratase - Methylobacillus flagellatus
           (strain KT / ATCC 51484 / DSM 6875)
          Length = 321

 Score = 89.8 bits (213), Expect = 1e-16
 Identities = 77/245 (31%), Positives = 117/245 (47%), Gaps = 20/245 (8%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQL-ILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 117
           V G +GFVG  + ++L   G  + +L  R +   ++ L +   L  V  T   + +E S+
Sbjct: 9   VVGGSGFVGSALVHRLSTAGYDVKVLTRRRE--SSKHLIL---LPNVQVTECDVFNEASL 63

Query: 118 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 177
           +  +   + VINL G  +E+ N  +  +HVD   RIA IC ++GV R +H+S L A    
Sbjct: 64  SGQLHGQDAVINLAGILHESGNATFESIHVDLATRIADICCKQGVPRLLHMSALKASADA 123

Query: 178 KPLVLKKPSAWKISKYLGECAV--REEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNL 235
           K       SA+  SK  GE AV  R +    T+ R S I+G  D FL  L N +    N+
Sbjct: 124 K-------SAYLRSKAAGEQAVLRRADELQVTVFRPSVIFGRGDHFLSMLANVV----NM 172

Query: 236 MPLYKNGLATVK-QPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLM 294
           MP+        K QP++V DVA   + A  +  T        GP+ Y L  L++    L+
Sbjct: 173 MPVVAVAKPNAKFQPIWVEDVAYVFLTALENVSTYGRSIDLGGPQVYTLKQLIELTALLL 232

Query: 295 RKDEK 299
            K  +
Sbjct: 233 GKKRR 237


>UniRef50_Q6G583 Cluster: NADH-ubiquinone oxidoreductase; n=3;
           Bartonella|Rep: NADH-ubiquinone oxidoreductase -
           Bartonella henselae (Rochalimaea henselae)
          Length = 334

 Score = 89.4 bits (212), Expect = 1e-16
 Identities = 85/331 (25%), Positives = 150/331 (45%), Gaps = 18/331 (5%)

Query: 58  TVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 117
           TVFG +GFVGR+V   L K G ++ +  R        L++ G++GQ       +    S+
Sbjct: 17  TVFGGSGFVGRHVVEALTKRGYRVRIAVRSPQKAYYMLQI-GEVGQTQMLRTDIKCRASV 75

Query: 118 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 177
           A+A+  S+  + L G   +     +    ++G + ++ +  E G+   I++S L A ++ 
Sbjct: 76  ARALLGSDGAVFLPGSLAQANQPNFQKTQIEGAQNVSELTAEAGIP-LIYMSALVANKNA 134

Query: 178 KPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMP 237
             L  +  S       + E  +  E+P A I+R S I+G ED F  +L N +     ++P
Sbjct: 135 SFLYARVKS-------MSEEIIHNEHPQAIIMRPSIIFGPEDCFFNNLAN-LSCFLPIIP 186

Query: 238 LYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLM-RK 296
           L+  G + + QPV+V DVA+ IV A        + Y   GP+     +++++  K++ RK
Sbjct: 187 LFGGGQSKL-QPVYVGDVAEFIVRALEGQVISGKSYDLGGPQIITFQNVLEYILKIIHRK 245

Query: 297 DEKWGGYIRYDMKYDPILPL--KVALVNAISPAYPLGNLHWEGIEREATSDNVVIGVPTL 354
                  +   +    +L    K+ L   +  A  +  L  + I  +   +N      TL
Sbjct: 246 KTILSMPLSAGLFIGGLLGTIGKLPLAPTLVTASQIRFLQIDNIVSQEAIENGY----TL 301

Query: 355 EDLGVTLTHMEDQVPWELKPFRAHQYYMDRL 385
           E +G+T   M   +P  L  FR H  +   L
Sbjct: 302 EGVGITPKAMAALLPSYLWRFRPHGQFSRNL 332


>UniRef50_A1WZI3 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Halorhodospira halophila SL1|Rep: NAD-dependent
           epimerase/dehydratase - Halorhodospira halophila (strain
           DSM 244 / SL1) (Ectothiorhodospirahalophila (strain DSM
           244 / SL1))
          Length = 320

 Score = 86.6 bits (205), Expect = 1e-15
 Identities = 76/241 (31%), Positives = 109/241 (45%), Gaps = 19/241 (7%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           V G TGFVG +V N+L   G ++    R        L   G   ++     H  DE  + 
Sbjct: 8   VVGGTGFVGMHVANRLADRGYRIRALTRRSHRGRDLLLFPGL--RLFEADVH--DERELV 63

Query: 119 KAVRYSNVVINLVGRDYET---KNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 175
           +     + VINL G        +   Y++VHVD  RR+    R   V R +H+S L A  
Sbjct: 64  RHFSGCHAVINLAGAHTGRGGPREDAYHEVHVDLPRRVLAAARRASVPRLVHMSALGA-- 121

Query: 176 HPKPLVLKKPSAWKISKYLGECAVREEYPT---ATIIRASDIYGSEDRFLRSLVNKMRSH 232
           HP  +     S +  +K  GE  V    P    AT+++ S I+G+ DRFL      +R  
Sbjct: 122 HPDAV-----SRFLRTKGEGEQLVLAADPDEIGATVLQPSVIFGAGDRFLNRFAGLLRFA 176

Query: 233 SNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYK 292
             +  L         QPVF  DVAQ ++NA  D  T  + YQ  GP+ Y L +LV++  +
Sbjct: 177 PGVFFLPTPDARL--QPVFGGDVAQAVINATEDPRTAGQTYQLCGPQIYTLRELVEYVAE 234

Query: 293 L 293
           L
Sbjct: 235 L 235


>UniRef50_A6GU58 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Limnobacter sp. MED105|Rep: NAD-dependent
           epimerase/dehydratase - Limnobacter sp. MED105
          Length = 317

 Score = 85.0 bits (201), Expect = 3e-15
 Identities = 70/238 (29%), Positives = 117/238 (49%), Gaps = 24/238 (10%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           V G +GF+G+ VCN+L K G ++ +P R   YD  +  +     Q++    H  D  ++ 
Sbjct: 2   VIGGSGFLGQAVCNQLAKAGYRITVPTRR--YDKAKHLLTLPTCQIIEANIH--DRATLG 57

Query: 119 KAVRYSNVVINLVGRDYET------KNFKYNDVHVDGVRRIARICREEGVERFIHLSYLN 172
           + V   ++V+NL+G  +        +NF+ N  HV+  + +     + G +R +H+S L 
Sbjct: 58  RLVSGQDIVVNLLGVLHSKPGKPYGQNFRVN--HVEFPKALCTAMSKHGAKRIVHVSALG 115

Query: 173 AE-EHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRS 231
              ++P P      S +  SK  GE  V++     TI+R S ++G ED+FL +  + +  
Sbjct: 116 VGVQNPAP------SMYLRSKTDGEAVVKDSGLAWTILRPSVVFGREDKFLNTFAS-LAK 168

Query: 232 HSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDD--DTKCEVYQAVGPKRYLLADLV 287
            +  +PL   G     QPV VSDVA+ +     D   DT    Y  VG + + L +LV
Sbjct: 169 IAPFIPL--AGADARFQPVSVSDVAKAVFACVEDQGKDTLHNTYDLVGTEIFTLKELV 224


>UniRef50_A6FZ88 Cluster: Probable NADH-ubiquinone oxidoreductase;
           n=1; Plesiocystis pacifica SIR-1|Rep: Probable
           NADH-ubiquinone oxidoreductase - Plesiocystis pacifica
           SIR-1
          Length = 554

 Score = 85.0 bits (201), Expect = 3e-15
 Identities = 78/246 (31%), Positives = 118/246 (47%), Gaps = 29/246 (11%)

Query: 55  IVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCG-DLGQVLFT-PYHLL 112
           +   V G +GF+GR+V + L   G ++++  RG     + L+  G +L +V F  P+   
Sbjct: 2   LTVAVAGGSGFIGRHVVDHLRAQGCRVVVLARG----LRGLEGEGVELRRVDFAGPW--- 54

Query: 113 DEESIAKAVRYSNVVINLVG--RDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSY 170
             E  A  +   + V+NLVG  R        +   HV+  + +A   R EG+ERF+H+S 
Sbjct: 55  -SEQGASLLAGCDAVVNLVGIKRAGRGSGLSFEAAHVELPKALAEAARREGIERFVHVSV 113

Query: 171 LNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMR 230
             A  HP+       S +  +K  GE AVRE +P ATI+R   +YG  D  LR+L + +R
Sbjct: 114 AGARRHPR-------STYLDTKARGEAAVREGFPAATILRPGVVYGRGDDMLRNLADSVR 166

Query: 231 S----HSNLMPLYKNGLATVKQ----PVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYL 282
           +     +   P    G  T       PV V DVA+ +  A  +   + +V   VGP R  
Sbjct: 167 AAPVFPAPRRPRSATGTGTGTWAELCPVAVEDVAEAVWRAV-EGRGQGQVLDVVGP-RTT 224

Query: 283 LADLVD 288
           L  LVD
Sbjct: 225 LPRLVD 230


>UniRef50_Q1PXS0 Cluster: Similar to dehydratase OleE [Streptomyces
           antibioticus]; n=1; Candidatus Kuenenia
           stuttgartiensis|Rep: Similar to dehydratase OleE
           [Streptomyces antibioticus] - Candidatus Kuenenia
           stuttgartiensis
          Length = 297

 Score = 84.2 bits (199), Expect = 5e-15
 Identities = 62/236 (26%), Positives = 114/236 (48%), Gaps = 15/236 (6%)

Query: 61  GCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKA 120
           G TGFVG+ + NKL +   ++    R         K+   + Q+      + D   +  A
Sbjct: 7   GSTGFVGKQLLNKLIENKYKVKCLVR----KGSEHKLGQYINQIEVVNGDITDPPCLKNA 62

Query: 121 VRYSNVVINLVG--RDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 178
           +     VIN+VG  R+   K   +  +H +G   + R  +++GV+RFI +S L A++  K
Sbjct: 63  IADCEAVINIVGIIREIPGKGVTFEKLHYEGTHNLIREAKKQGVDRFIQMSALGAKQEGK 122

Query: 179 PLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPL 238
            L       ++ +K+L E  +R+     TI R S I+G ED+F+ +    ++     +P+
Sbjct: 123 TL-------YQQTKFLAEECIRKSGLNYTIFRPSIIFGKEDKFVNTFAGMLKI-QQFIPV 174

Query: 239 YKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLM 294
             +G   + QPV V +V    V++    DT  + Y+  GP++    D+++   K++
Sbjct: 175 IGDGKYKL-QPVAVENVVAAFVDSIERRDTFGKSYEVGGPEKIEFNDIINIIGKVL 229


>UniRef50_Q1YEV9 Cluster: NADH-ubiquinone oxidoreductase; n=7;
           Alphaproteobacteria|Rep: NADH-ubiquinone oxidoreductase
           - Aurantimonas sp. SI85-9A1
          Length = 369

 Score = 82.2 bits (194), Expect = 2e-14
 Identities = 66/238 (27%), Positives = 116/238 (48%), Gaps = 11/238 (4%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           VFG +GFVGRY+   L + G ++ +  R     A  L+  G++GQ++    +L    S+ 
Sbjct: 46  VFGGSGFVGRYLVQALARRGHRIRVACRRPDL-AYHLQPNGNMGQIMPIQANLRYPWSVE 104

Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 178
           +AV  ++ V+NLVG   ++    ++ +   G R +A    + G      +S + A+E+  
Sbjct: 105 RAVEGADHVVNLVGILAQSGQQSFDALQSFGARTVAEATAKIGAG-MTQISAIGADEN-- 161

Query: 179 PLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPL 238
                  S +  +K  GE AV +  P A I+R S ++G+ED+F     + M   S  +PL
Sbjct: 162 -----SGSEYARTKAEGEKAVLDAIPGAYIMRPSIVFGAEDQFFNRFAD-MARFSPFLPL 215

Query: 239 YKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMRK 296
              G  T  QPV+V DVA+ I +          VY+  GP+      +++   +++ +
Sbjct: 216 IGGG-KTRFQPVYVGDVAEAIADTVDGKVPGGRVYELGGPEVLTFRQMMEEMLRIIER 272


>UniRef50_A5P8M1 Cluster: NADH ubiquinone oxidoreductase, putative;
           n=3; Erythrobacter|Rep: NADH ubiquinone oxidoreductase,
           putative - Erythrobacter sp. SD-21
          Length = 344

 Score = 82.2 bits (194), Expect = 2e-14
 Identities = 84/339 (24%), Positives = 153/339 (45%), Gaps = 34/339 (10%)

Query: 51  SFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYH 110
           + NG    + G TGF+G YV   L   G +L +  R     A +LK   +LGQ+ F    
Sbjct: 34  ALNGKTVALMGGTGFLGNYVAQALLSRGARLRICGRNP-QAAFKLKPLANLGQLQFARMD 92

Query: 111 LLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRR--IARICREEGVERFIHL 168
             D  S+ + ++ ++ V+NLVG      +F  +   + G     +A   ++ G   F+H+
Sbjct: 93  ATDRRSVEQCIKGADAVVNLVG------SFDGDLARLMGEAPGWMAEAAKKTGAMSFVHV 146

Query: 169 SYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNK 228
           S + AE           + +  +K++GE  V E +  ATI+R S I+G +D FL ++  +
Sbjct: 147 SAIAAEPEED-----WSNEYASAKHMGERRVTEAFKNATIVRPSIIFGKDDNFL-NMFGE 200

Query: 229 MRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTK-CEVYQAVGPKRYLLADLV 287
           + S   ++P++  G     Q V+V DVA+ I  +  +      + Y+  GP++  + ++ 
Sbjct: 201 LISKLPVLPVF--GPEAELQLVYVDDVAEAIAQSVENPGKHGGKTYELGGPEKLSMIEI- 257

Query: 288 DWFYKLMRKDEKWGGYIRYDMKYDPILPLKVALVNAISPAYPLGNLHWEGIEREATSDNV 347
                    + +     R    + P +P  V+   A  P  P+G+  W+ +++     NV
Sbjct: 258 ---------NRRIADAQRRKRTFLP-MPDGVSATFAALPGTPMGSDQWDLLKQ----GNV 303

Query: 348 VIG-VPTLEDLGVTLTHMEDQVPWELKPFRAHQYYMDRL 385
             G  P  E  G+    +   +   +  FR H  + +RL
Sbjct: 304 ASGDYPGFEKFGIEPKPLGLFLDKWMTRFRKHGRFAERL 342


>UniRef50_Q5FPV9 Cluster: Putative oxidoreductase; n=1;
           Gluconobacter oxydans|Rep: Putative oxidoreductase -
           Gluconobacter oxydans (Gluconobacter suboxydans)
          Length = 340

 Score = 81.8 bits (193), Expect = 3e-14
 Identities = 93/323 (28%), Positives = 144/323 (44%), Gaps = 29/323 (8%)

Query: 54  GIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLD 113
           G V  V G  GFVGR +  +L   G  + +       D    +  GD G+V F    + D
Sbjct: 32  GRVVAVLGGGGFVGRELVGRLVASGHVVRVGSGNPEADQALARFPGD-GRVEFIKASVND 90

Query: 114 EESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA 173
            +S+      ++  INLV          +  V+V+G R  A + R EGVE+++H+S + A
Sbjct: 91  ADSLEHLFSGADAGINLVSIMSPDVKAMHR-VNVEGARLAALVARREGVEQYLHMSAIGA 149

Query: 174 EEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLR--SLVNKMRS 231
                   ++ P  +  SK L E  VRE +P A ++R S I+G ED F    +L+ K+  
Sbjct: 150 S-------IQSPGNYGRSKGLAERVVREVFPEAALLRPSVIFGPEDSFFNMFALIAKL-- 200

Query: 232 HSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFY 291
            S ++P++  G+    QPV+V DVA+  +     +     V +A GP    + +L+ +  
Sbjct: 201 -SPVLPVFAAGMRF--QPVYVGDVARAAMALVTPERAGMTV-EAGGPDVLTMKELMAFVL 256

Query: 292 KLMRKDEKWGGYIRYDMKYDPILPLKVALVNAISPAYPLGNLHWEGIEREATSDNVV-IG 350
           +         G  R+ +   P+      L   I    P G+L           DNVV  G
Sbjct: 257 EA-------SGRRRFLL---PVPDCVAKLEAEILEPLP-GHLLTRDQVVMMGLDNVVQPG 305

Query: 351 VPTLEDLGVTLTHMEDQVPWELK 373
              L+ LG+T T M   VP  LK
Sbjct: 306 ADDLQSLGITPTAMRSVVPDYLK 328


>UniRef50_A4T0E5 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Polynucleobacter sp. QLW-P1DMWA-1|Rep: NAD-dependent
           epimerase/dehydratase - Polynucleobacter sp.
           QLW-P1DMWA-1
          Length = 302

 Score = 80.6 bits (190), Expect = 7e-14
 Identities = 70/235 (29%), Positives = 114/235 (48%), Gaps = 17/235 (7%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDE-ESI 117
           + G  GFVGR +  +L   G  +++P        + L++   +  +     H  DE +++
Sbjct: 7   LIGGNGFVGRVIAAQLQAAGYSVLIP-TSHVVAGRELRLLPKV-HLEDADVHDFDELQNL 64

Query: 118 AKAVRYSNVVINLVGRDYETKNFKYNDV----HVDGVRRIARICREEGVERFIHLSYLNA 173
              ++    VINLVG  ++ +   Y  V    HVD  + I    +  G++R++H+S L A
Sbjct: 65  CGRIQLRGAVINLVGVLHDKEAQPYGKVFKAAHVDLPKNIITAMQLHGLKRYLHMSALGA 124

Query: 174 EEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHS 233
                    + PS ++ SK  GE AV+      TI R S I+G++D+F+ +L +K+    
Sbjct: 125 NS-------QGPSMYQRSKGDGELAVKASSLDWTIFRPSVIFGAQDQFI-NLFSKLTKLF 176

Query: 234 NLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVD 288
             +PL  N  A   QPV V DVA   V A     T  +VY  VGP  Y + ++V+
Sbjct: 177 PALPL-ANYQAQF-QPVSVDDVASAFVGALTMPQTIHQVYDLVGPTVYSMKEIVE 229


>UniRef50_Q0F0X9 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Mariprofundus ferrooxydans PV-1|Rep: NAD-dependent
           epimerase/dehydratase - Mariprofundus ferrooxydans PV-1
          Length = 317

 Score = 80.2 bits (189), Expect = 9e-14
 Identities = 67/231 (29%), Positives = 106/231 (45%), Gaps = 17/231 (7%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           V G +GFVGR +  +    G  + +  R     A+ + V G    V      ++D   I 
Sbjct: 7   VIGGSGFVGRAIAKQAVTAGHTVTVGCRHP-ERARAMLVDG----VRLKRVDVVDGRGID 61

Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 178
           +A++  + VI LVG  +E   + +   HVDGV  +   C+  GV +++H+S L A   P 
Sbjct: 62  EAIKGCDTVIYLVGLLFERGRYNFQAAHVDGVEHVLAACQRAGVGQYLHMSALGAGAVP- 120

Query: 179 PLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPL 238
                  S++  SK   E  VR      TI R S IYG+ D F     +K ++ S+ +P+
Sbjct: 121 ------GSSYATSKGEAEKHVRASGLNWTIFRPSIIYGAGDSFF----SKFKTISSALPV 170

Query: 239 YKNGLATVK-QPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVD 288
                   + QPV+V DVA+  V    +  T  + Y+  GP  Y    L++
Sbjct: 171 MPVICGETRFQPVWVEDVARAFVGTIGNRHTANQCYELGGPATYSFKQLLE 221


>UniRef50_UPI0000E87D4F Cluster: NAD-dependent
           epimerase/dehydratase; n=1; Methylophilales bacterium
           HTCC2181|Rep: NAD-dependent epimerase/dehydratase -
           Methylophilales bacterium HTCC2181
          Length = 293

 Score = 79.4 bits (187), Expect = 2e-13
 Identities = 60/235 (25%), Positives = 120/235 (51%), Gaps = 21/235 (8%)

Query: 56  VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPY-HLLDE 114
           V ++FG TGF+G  + ++L K   ++ L          R K+   L  +  T +  L D+
Sbjct: 3   VVSIFGGTGFIGTELIHELEKKNYEIRL--------FTRRKIPHTLNTLSKTRFIQLRDD 54

Query: 115 ESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 174
             ++  +  S+++I+LVG  +E K   ++DVH   ++++++I ++  ++RFIH+  L A 
Sbjct: 55  TKLSNELIGSDIIIDLVGILHEQKGITFDDVHSGRLKKLSKIAQKLNIKRFIHIGALGAS 114

Query: 175 EHPKPLVLKKPSAWKISKYLGECAVREEYPTA--TIIRASDIYGSEDRFLRSLVNKMRSH 232
                  +  PS +  SK  GE  ++++      TI + S ++G +D+F+ +L + + S 
Sbjct: 115 -------VNAPSKYLQSKGKGEKHIKKQCSNLAWTIYKPSIVFGIDDKFV-NLFHNIISF 166

Query: 233 SNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287
           + ++ L      ++ QP++V D+   I+N   D  T  + +   GP  Y    L+
Sbjct: 167 TPIIGLISP--HSMFQPIWVKDLVDIIINGIDDKKTFQKTFNVAGPTSYSFMGLI 219


>UniRef50_UPI0000F21730 Cluster: PREDICTED: hypothetical protein;
           n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 392

 Score = 79.0 bits (186), Expect = 2e-13
 Identities = 40/95 (42%), Positives = 61/95 (64%), Gaps = 7/95 (7%)

Query: 139 NFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECA 198
           N+KY DV V    +IAR  RE G+++FIH+S+LNA+       ++ PS +  +K +GE A
Sbjct: 302 NYKYEDVFVSIPLQIARATREAGIKKFIHMSHLNAD-------IRSPSKYLRNKAVGEEA 354

Query: 199 VREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHS 233
           VR E+P A I++ S+++G EDRFL    +K   +S
Sbjct: 355 VRNEFPDAIIMKPSELFGREDRFLNHFASKCLENS 389


>UniRef50_A5FQ11 Cluster: NAD-dependent epimerase/dehydratase; n=3;
           Dehalococcoides|Rep: NAD-dependent epimerase/dehydratase
           - Dehalococcoides sp. BAV1
          Length = 302

 Score = 77.4 bits (182), Expect = 6e-13
 Identities = 64/237 (27%), Positives = 113/237 (47%), Gaps = 14/237 (5%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           V G +GFVGR++  +L + G ++ L    +  +A R+K  G    V F    + D   + 
Sbjct: 7   VTGGSGFVGRHLLPRLAENGFKIRLLVMNET-EANRVKTPG----VEFVYGTVNDLPVLM 61

Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 178
            +++    +I+LV    E KN  + +V+++G + +     E GV+RFIH+  L A   P+
Sbjct: 62  DSLKDVFAIIHLVAILRENKNATFAEVNIEGTKNMLAAATENGVKRFIHMGILGASADPR 121

Query: 179 PLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPL 238
              L        SKYL E AVR      +I++ S ++G    F+ +L+   + +  + P+
Sbjct: 122 FTYLH-------SKYLAEEAVRHSGLGYSILKPSVMFGPGAGFINALIRSFKPYPCIAPV 174

Query: 239 YKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMR 295
             NG  T  QP++V DV   ++     +     V Q  GP+ +    ++    + MR
Sbjct: 175 AGNG-KTRLQPIWVEDVVSCLLKMLEGEKIHQSV-QIGGPQIFTYDQVLSAVMQAMR 229


>UniRef50_Q5P3S8 Cluster: Predicted nucleoside-diphosphate-sugar
           epimerases; n=4; Betaproteobacteria|Rep: Predicted
           nucleoside-diphosphate-sugar epimerases - Azoarcus sp.
           (strain EbN1) (Aromatoleum aromaticum (strain EbN1))
          Length = 321

 Score = 77.0 bits (181), Expect = 8e-13
 Identities = 69/241 (28%), Positives = 108/241 (44%), Gaps = 20/241 (8%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           + G +GF+G  V N+L     ++++P R     A R +    L  V      + D  ++A
Sbjct: 8   LIGGSGFLGSAVANQLAGAAVEVVVPTRR----ASRARHLLLLPTVDVVEADVHDPATLA 63

Query: 119 KAVRYSNVVINLVGRDYETKNFKYND----VHVDGVRRIARICREEGVERFIHLSYLNAE 174
             V   + VINLVG  +      Y       HV+  ++I   C    V   +H+S L A 
Sbjct: 64  HLVSGVDAVINLVGILHSRSGSPYGRDFARAHVELPQKIVAACHAARVPHLVHVSALGAS 123

Query: 175 EHPKPLVLKKPSAWKISKYLGECAVRE--EYPTATIIRASDIYGSEDRFLRSLVNKMRSH 232
                     PS +  SK  GE A+R   + P  T++R + ++G  D F  +L  ++ + 
Sbjct: 124 PDG-------PSEYLRSKAAGEAAIRASGDAPAWTVLRPAVMFGRGDHFT-NLFARLATR 175

Query: 233 SNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYK 292
             L+PL   G     QPV V DVA  I    RD     E ++  GP+ Y L +LV++  +
Sbjct: 176 FPLLPLA--GARARFQPVHVEDVAAVICRCLRDPAAIGETFELAGPRVYTLRELVEYISE 233

Query: 293 L 293
           L
Sbjct: 234 L 234


>UniRef50_A0L6A2 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Magnetococcus sp. MC-1|Rep: NAD-dependent
           epimerase/dehydratase - Magnetococcus sp. (strain MC-1)
          Length = 294

 Score = 75.8 bits (178), Expect = 2e-12
 Identities = 49/173 (28%), Positives = 86/173 (49%), Gaps = 9/173 (5%)

Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 175
           S+  A+     VI+LVG   E ++  + ++H  G   + +  ++ GV+RF+H+S L    
Sbjct: 54  SLQTAMEGVTCVIHLVGILAEQRHRSFEEIHHQGTLNVLQAAKQAGVKRFLHMSSLGTRA 113

Query: 176 HPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNL 235
           +         + +  SK+  ECAVRE     TI R S I+G  D F+      +R  S +
Sbjct: 114 N-------AVARYHQSKWQAECAVRESGLDYTIFRPSVIFGPGDNFVNQFARMIR-FSPM 165

Query: 236 MPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVD 288
           +P+  +G   + QP+ V DVA+    A  D  T  + Y+  GP++    ++++
Sbjct: 166 VPILGDGQNRM-QPIAVGDVARCFAIALTDRQTLGQTYELGGPQQLTFQEIME 217


>UniRef50_A7BKW7 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Beggiatoa sp. SS|Rep: NAD-dependent
           epimerase/dehydratase - Beggiatoa sp. SS
          Length = 263

 Score = 74.9 bits (176), Expect = 3e-12
 Identities = 72/243 (29%), Positives = 119/243 (48%), Gaps = 26/243 (10%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQL-ILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 117
           + G TGFVG+ + N+L K+G Q+ +L  R +  + + L V   L ++L T Y   D+  +
Sbjct: 6   LLGGTGFVGKQLANRLFKMGWQVRVLTRRRE--EHRELLVLPTL-ELLSTNY---DQAQL 59

Query: 118 AKAVRYSNVVINLVG----RDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA 173
            +  R  +VVINLVG      ++ K F+    HV+  +++   C+E  ++R +H+S LNA
Sbjct: 60  NEQTRGCDVVINLVGILNESGHDGKGFQ--KAHVELPQKVIAACQENKIKRLLHISALNA 117

Query: 174 EEHPKPLVLKKPSAWKISKYLGECAVREEYPT-ATIIRASDIYGSEDRFLRSLVNKMRSH 232
           +        +K S +  +K   E  +        T  R S I+G  D FL   V+ +R  
Sbjct: 118 D------ATQKNSHYLRTKGEAEDLIHAVSDVHVTSFRPSVIFGEGDSFLNRFVSMLRVP 171

Query: 233 SN--LMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWF 290
           S   ++P +   LA    PV+V+DV + ++    +     E Y   G   Y L +LV + 
Sbjct: 172 SPIFMLPSFDAKLA----PVWVNDVVRAMLEVVENPQYDGERYNFCGGSVYTLQELVAYL 227

Query: 291 YKL 293
            KL
Sbjct: 228 AKL 230


>UniRef50_Q2Y682 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Nitrosospira multiformis ATCC 25196|Rep: NAD-dependent
           epimerase/dehydratase - Nitrosospira multiformis (strain
           ATCC 25196 / NCIMB 11849)
          Length = 312

 Score = 74.5 bits (175), Expect = 4e-12
 Identities = 66/231 (28%), Positives = 102/231 (44%), Gaps = 19/231 (8%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           +FG +GFVG+++ N L      L +P R    + +R K   ++         + D+  + 
Sbjct: 8   IFGGSGFVGKHLANLLTNREIYLRIPTR----NYERAKELLEIPTTDLIEADIYDDRDLD 63

Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 178
           + +   + VINLVG         ++ VHV+  ++I   C+  G+ R +H+S L A     
Sbjct: 64  RLLLGIDAVINLVG----VLQGDFHAVHVELPQKIIAACKRNGITRILHMSALKAGPG-- 117

Query: 179 PLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPL 238
                +PS +  SK  GE  VR     AT+ R S I+G  D    S +N       L  L
Sbjct: 118 -----QPSEYLRSKGEGEQIVRTSGMDATVFRPSVIFGPGD----SSINLFARLGRLPVL 168

Query: 239 YKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDW 289
                    QP+FV DV Q    +  +  T    Y   GPK Y L +LV++
Sbjct: 169 PLASPHAKFQPIFVMDVVQAFALSLDEPRTFGRSYDLCGPKCYSLRELVEY 219


>UniRef50_Q1K3T7 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Desulfuromonas acetoxidans DSM 684|Rep: NAD-dependent
           epimerase/dehydratase - Desulfuromonas acetoxidans DSM
           684
          Length = 297

 Score = 74.5 bits (175), Expect = 4e-12
 Identities = 63/230 (27%), Positives = 101/230 (43%), Gaps = 17/230 (7%)

Query: 61  GCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKA 120
           G TGFVG +V   L   G  +    R      +       L QV      + +   + +A
Sbjct: 7   GATGFVGHHVIQALLLNGHTVRCLVR------KPTPSLTSLVQVETVQGDITNPAELKQA 60

Query: 121 VRYSNVVINLVG--RDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 178
           +   + +I+LVG  R +  +   +  +HV+  R I     E G++R++H+S   A     
Sbjct: 61  MSDCDAIIHLVGIIRAFPQRGITFEKLHVEATRNIITAAAEAGIDRYLHMSANGASPDC- 119

Query: 179 PLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPL 238
                 P A+  +K+  E  VR+   T TI R S I+G +  F R L+ ++R    ++P+
Sbjct: 120 ------PEAYGATKWRAEELVRQSRLTWTIFRPSLIFGPDGEFTRMLIQQLR-FLPMIPI 172

Query: 239 YKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVD 288
             +G   +  PV V DVA G  NA        ++Y   GP      DL+D
Sbjct: 173 IGDGHYQL-SPVNVDDVALGFANALSSPQAIGKIYHCCGPDTCSYNDLID 221


>UniRef50_Q1WMR0 Cluster: Putative nucleoside-diphosphate-sugar
           epimerase; n=1; Coprinellus disseminatus|Rep: Putative
           nucleoside-diphosphate-sugar epimerase - Coprinellus
           disseminatus
          Length = 330

 Score = 74.1 bits (174), Expect = 6e-12
 Identities = 57/178 (32%), Positives = 94/178 (52%), Gaps = 16/178 (8%)

Query: 115 ESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 174
           E++  A   ++ V++LVG  Y  K   +  +   G   +A+  ++ G  R IH+S + A 
Sbjct: 75  ETLTPAFEGAHTVVSLVGVMYG-KPADFERIQWRGAENVAKAAQKAGA-RLIHISAIGA- 131

Query: 175 EHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSN 234
            +P   +    S W+ +K LGE AVR  +PTATIIR S ++G ED F     +K+     
Sbjct: 132 -NPSSDI----SYWR-TKGLGEEAVRSVHPTATIIRPSLVFGPEDDFFNRF-SKLSKFLP 184

Query: 235 LMPLYKNGLATVKQPVFVSDVAQGIVNAARDD-----DTKCEVYQAVGPKRYLLADLV 287
            +P++  G A + QPV+V D+A+ I   +R D     +   ++ +A GP+ Y   DL+
Sbjct: 185 FLPVFGGGQA-MFQPVYVDDIAKAIEVMSRGDPEVEKEISGKIIEAGGPRVYTYYDLM 241


>UniRef50_Q3JE30 Cluster: NAD-dependent epimerase/dehydratase; n=2;
           Chromatiales|Rep: NAD-dependent epimerase/dehydratase -
           Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
          Length = 320

 Score = 73.7 bits (173), Expect = 8e-12
 Identities = 61/238 (25%), Positives = 106/238 (44%), Gaps = 11/238 (4%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           + G TGFVGR++ + L + G ++ +  R      QR +    L  +      + D   +A
Sbjct: 8   ILGGTGFVGRWLSSHLVEQGYKVRVLTR----HWQRHRDLLVLPGLRLMETDVYDPAQLA 63

Query: 119 KAVRYSNVVINLVG--RDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEH 176
                   VINL+G   +       +  VH D   ++A+IC + G++R +H+S LNA+ +
Sbjct: 64  AQFNGCQSVINLIGILNEKGRNGHGFRQVHADLPEKVAQICLDTGIKRLLHMSALNADAN 123

Query: 177 PKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLM 236
                  +      ++ L   A+  +    TI + S I+G  D F     + ++    + 
Sbjct: 124 QGASYYLRSKGEGENRVL---ALARQGLEVTIFQPSVIFGPGDSFFNRFGSLLKLSPFIF 180

Query: 237 PLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLM 294
           PL          PV+V DVA+    A  D +   + Y+  GPK Y L  LV++  K++
Sbjct: 181 PLACPEARLT--PVYVGDVARAFARALSDKEDFSQSYELCGPKIYTLKQLVEYTAKVL 236


>UniRef50_Q7NWF7 Cluster: Probable NADH-ubiquinone oxidoreductase;
           n=1; Chromobacterium violaceum|Rep: Probable
           NADH-ubiquinone oxidoreductase - Chromobacterium
           violaceum
          Length = 313

 Score = 72.9 bits (171), Expect = 1e-11
 Identities = 59/228 (25%), Positives = 103/228 (45%), Gaps = 16/228 (7%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           + G +GF+GR++  +L   G ++ +  R       R+    +L   +    H  D   +A
Sbjct: 8   LIGGSGFIGRHLAAQLASRGHRITIASRRTGLPDFRVLPSAEL---VSADIH--DPGQLA 62

Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 178
             +   + V+++VG  + ++  ++   H     +I   CR +GV R +H+S L A +   
Sbjct: 63  GLIAGHDAVVSMVGILHGSRA-QFEKAHAQLPEKIVDACRRQGVRRLVHVSALGAAQDA- 120

Query: 179 PLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPL 238
                 PS ++ +K LGE AV       TI+R S ++G  D FL      ++    ++PL
Sbjct: 121 ------PSDYQQTKALGELAVESSGLDWTILRPSVVFGHGDAFLNMFAG-LQKRLPVLPL 173

Query: 239 YKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADL 286
              G      PV+V DVA+ +       +T+       GP+ Y LA L
Sbjct: 174 --AGAGCKMAPVWVEDVARAVCECLARKETEGRKLDLAGPETYTLAQL 219


>UniRef50_Q39C42 Cluster: NAD-dependent epimerase/dehydratase; n=30;
           Burkholderiales|Rep: NAD-dependent epimerase/dehydratase
           - Burkholderia sp. (strain 383) (Burkholderia cepacia
           (strain ATCC 17760/ NCIB 9086 / R18194))
          Length = 319

 Score = 72.5 bits (170), Expect = 2e-11
 Identities = 71/238 (29%), Positives = 106/238 (44%), Gaps = 25/238 (10%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           + G TGF+G  + N L + G Q+ +  R   + A+ L++      V       LD  ++A
Sbjct: 8   LLGGTGFIGSRLVNALIESGKQVRIGTRRRDH-ARHLQML----PVEVVELEALDTRTLA 62

Query: 119 KAVRYSNVVINLVGRDYETKNFKYND----VHVDGVRRIARICREEGVERFIHLSYLNAE 174
           + V  ++  INLVG  +  +   Y       HV     +A  C E GV R +H+S L A+
Sbjct: 63  RFVAGAHAAINLVGVLHGGRGTPYGPGFERAHVTLPAALATACTEVGVRRVLHMSALGAD 122

Query: 175 EHPKPLVLKKPSAWKISKYLGECAVREEYPT----ATIIRASDIYGSEDRFLRSLVNKMR 230
            H         S ++ SK  GE A+     T     TI R S ++G  D FL +  N  R
Sbjct: 123 SH-------GASMYQRSKGDGEAALHAIAATDSLALTIFRPSVVFGPGDAFLNTFANLQR 175

Query: 231 SHSNLMPLYKNGLATVK-QPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287
           S    +P+    +   + QPVFV DV +  VN      +  + Y+  GP  Y L  LV
Sbjct: 176 S----VPVLPLAMPDARFQPVFVGDVVRAFVNTLDLAASHGKTYELGGPTVYTLEQLV 229


>UniRef50_A3ES38 Cluster: Putative nucleoside-diphosphate-sugar
           epimerase; n=1; Leptospirillum sp. Group II UBA|Rep:
           Putative nucleoside-diphosphate-sugar epimerase -
           Leptospirillum sp. Group II UBA
          Length = 299

 Score = 71.3 bits (167), Expect = 4e-11
 Identities = 49/181 (27%), Positives = 90/181 (49%), Gaps = 9/181 (4%)

Query: 108 PYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIH 167
           P ++ D  S+A      ++V++L G   ETK+  Y  +HVDG R +    +   V R I+
Sbjct: 49  PGNVTDRGSLAPVFDGVDMVLHLTGILAETKSQSYEAIHVDGTRNVLDASKAGRVSRIIY 108

Query: 168 LSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVN 227
           LS + A    +       S +  +K   E  ++      TI R S ++G +D+FL +L  
Sbjct: 109 LSAIGASRTAR-------SRYHRTKAEAEDLLKNSGMDVTIFRPSVVFGKDDKFL-NLFA 160

Query: 228 KMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287
            M    +++PL  +G + V  PV+V+D+ + ++ + +  +T    YQ  G + Y   +L+
Sbjct: 161 GMGKTLHVLPLIGDGQSRV-HPVWVNDLVESVLESMKQPETVGRTYQMGGCRIYTYHELM 219

Query: 288 D 288
           +
Sbjct: 220 E 220


>UniRef50_Q560L2 Cluster: Putative uncharacterized protein; n=2;
           Filobasidiella neoformans|Rep: Putative uncharacterized
           protein - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 375

 Score = 71.3 bits (167), Expect = 4e-11
 Identities = 49/150 (32%), Positives = 80/150 (53%), Gaps = 10/150 (6%)

Query: 117 IAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEH 176
           + KA + ++ V++L G      + +   +  DG RR+     EEGV R + +S + A+  
Sbjct: 84  LRKAFKGASAVVSLAGL-LVGNDKQMKALQEDGARRVGEAASEEGVGRVVGVSAIGAD-- 140

Query: 177 PKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLM 236
                L+  +A+  +K  GE A+RE +PTATIIR S ++G  D F  S    +  +   +
Sbjct: 141 -----LRGVTAYWRTKAKGEDAIREYHPTATIIRPSLLFGPGDSFF-SRFATLAKYLPFL 194

Query: 237 PLYKNGLATVKQPVFVSDVAQGIVNAARDD 266
           P++  G+ T  QPV+V DVA+ +    RDD
Sbjct: 195 PVFGGGI-TRFQPVYVGDVARAVEICCRDD 223


>UniRef50_Q67SF4 Cluster: Putative NADH-ubiquinone oxidoreductase;
           n=1; Symbiobacterium thermophilum|Rep: Putative
           NADH-ubiquinone oxidoreductase - Symbiobacterium
           thermophilum
          Length = 303

 Score = 70.1 bits (164), Expect = 9e-11
 Identities = 84/319 (26%), Positives = 133/319 (41%), Gaps = 38/319 (11%)

Query: 56  VATVFGCTGFVGRYVCNKLGKIGTQLIL------PYRGDFYDAQRLKVCGDLGQVLFTPY 109
           V  V G TGF+G Y+  +L + G ++I+        RG   D   ++  GD+        
Sbjct: 3   VVLVAGGTGFIGSYIVRRLTQDGHRVIVMSRDPGKARGRVPDGVEVRA-GDVTDGATLGP 61

Query: 110 HLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLS 169
            L   E +  AV++ N  +    R +      Y  V  +G  R+    R+ GV RF+++S
Sbjct: 62  ALAGAEIVVCAVQFPNHPVENPRRGHT-----YIRVDGEGTVRLVGAARKAGVSRFVYIS 116

Query: 170 YLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKM 229
                E        KP  W  +K + E A+RE     TI R S +YG EDR L    NK 
Sbjct: 117 GAGTREGQT-----KP--WFRAKLMAEKAIRESGIPYTIFRPSWVYGPEDRSL----NKF 165

Query: 230 RSHSNLMPLYK--NGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287
            + + L+P         T  QP++V D+A  +  + R        Y   GP+   + +++
Sbjct: 166 ATFARLLPFVPVIGSGRTRVQPLYVEDLADAVAASLRTGAALNRTYDIGGPQELTMDEII 225

Query: 288 DWFYKLMRKDEKWGGYIRYDMKYDPILPLKVAL-VNAISPAYPLGNLHWEGIEREATSDN 346
                +M +        R  + + P   +K A       P  PL     + +  E   DN
Sbjct: 226 RTMLWVMGR--------RRPLLHSPAWLMKAAAWPLQFLPTPPLSPGAVDFVLMEEPVDN 277

Query: 347 VVIGVPTLEDLGVTLTHME 365
             +    L+DLG+TLT +E
Sbjct: 278 GQV----LQDLGLTLTPLE 292


>UniRef50_Q7NF91 Cluster: Gll3635 protein; n=1; Gloeobacter
           violaceus|Rep: Gll3635 protein - Gloeobacter violaceus
          Length = 298

 Score = 69.3 bits (162), Expect = 2e-10
 Identities = 55/228 (24%), Positives = 102/228 (44%), Gaps = 14/228 (6%)

Query: 61  GCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKA 120
           G TGF+G +    L + G  +    R    D   LK      +V     HL D+ S+ +A
Sbjct: 6   GATGFIGSHTARTLRERGLSVRALVRSGA-DTSALKAL----EVDLVVGHLDDKASLVRA 60

Query: 121 VRYSNVVINLVGRDYETK-NFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKP 179
               + +++LVG   E      +  +HV+G R +     E GV +F+++S + +    +P
Sbjct: 61  CTGVDAIVHLVGIIRELPPTVTFERIHVEGTRNLLAAATEAGVRKFVYISAIGS----RP 116

Query: 180 LVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLY 239
             + +   +  +K+  E  VR    T  I+R S ++G  D F+  L N +      +P+ 
Sbjct: 117 DAIAR---YHQTKWATEALVRSSGLTWVILRPSVVFGPGDEFINLLANDLVRKPPFIPVI 173

Query: 240 KNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287
             G   + QP++V D+A+ I            + +  GP++  L +++
Sbjct: 174 GPGTNKL-QPLWVKDLAEVIARCTTSSSFDGRILEVGGPEQLSLHEIL 220


>UniRef50_Q476T1 Cluster: NAD-dependent epimerase/dehydratase:3-beta
           hydroxysteroid
           dehydrogenase/isomerase:dTDP-4-dehydrorhamnose
           reductase; n=7; Burkholderiaceae|Rep: NAD-dependent
           epimerase/dehydratase:3-beta hydroxysteroid
           dehydrogenase/isomerase:dTDP-4-dehydrorhamnose reductase
           - Ralstonia eutropha (strain JMP134) (Alcaligenes
           eutrophus)
          Length = 340

 Score = 67.3 bits (157), Expect = 7e-10
 Identities = 54/167 (32%), Positives = 81/167 (48%), Gaps = 16/167 (9%)

Query: 126 VVINLVGRDYETKNFKYND----VHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPLV 181
           +V+NLVG  +  +   Y       HV+ V ++   C   GV R +H+S L A+       
Sbjct: 93  IVVNLVGVLHGERGDPYGPEFAAAHVEIVEQVVGSCLRTGVRRLLHMSALGADS------ 146

Query: 182 LKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKN 241
            + PS ++ SK  GE  VR+     T+ R S ++G +D FL +L   M+  + ++PL   
Sbjct: 147 -RGPSMYQRSKGDGERLVRDSGLDWTVFRPSVVFGPDDHFL-NLFAHMQEIAPVVPL--- 201

Query: 242 GLATVK-QPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287
             A  + QP++V DV Q  VNA     T    Y   GP  Y L +LV
Sbjct: 202 ACAHARFQPIYVLDVVQAFVNAMVTPATIGHGYDLGGPTVYTLEELV 248


>UniRef50_Q746J9 Cluster: NADH-ubiquinone oxidoreductase 39 kDa
           subunit/NADH dehydrogenase; n=2; Thermus
           thermophilus|Rep: NADH-ubiquinone oxidoreductase 39 kDa
           subunit/NADH dehydrogenase - Thermus thermophilus
           (strain HB27 / ATCC BAA-163 / DSM 7039)
          Length = 287

 Score = 66.5 bits (155), Expect = 1e-09
 Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 26/231 (11%)

Query: 59  VFGCTGFVGRYVCNKLGKIG-TQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 117
           V G TGFVGR V   L   G T L+L  R        + V GD+ +       + D E  
Sbjct: 5   VVGGTGFVGREVVRLLLARGHTPLVLARRSRPLPEGAVLVEGDIAR------EVPDLEG- 57

Query: 118 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 177
           A+A  Y   +I   G+ +         VHV+GVR + R     GV R +H+S L A    
Sbjct: 58  AEAAIYLAGIIRERGQTFRA-------VHVEGVRNLLRAMERAGVGRLLHMSALGA---- 106

Query: 178 KPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFL-RSLVNKMRSHSNLM 236
           +P   + PS +  +K  GE  VR+   +  I R S I+G  D F  R L   + +    +
Sbjct: 107 RP---EAPSRYHRTKAEGEALVRQSGLSHAIFRPSLIFGPGDEFFGRVLRGLVCAPLPFV 163

Query: 237 PLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287
           PL  +G     +PV+V DVA+  V A   +      Y  VGPK Y   +L+
Sbjct: 164 PLIGDG-GFPFRPVYVGDVAEAFVGAL--ERGLEGTYDLVGPKEYSFRELL 211


>UniRef50_Q31J38 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Thiomicrospira crunogena XCL-2|Rep: NAD-dependent
           epimerase/dehydratase - Thiomicrospira crunogena (strain
           XCL-2)
          Length = 323

 Score = 66.5 bits (155), Expect = 1e-09
 Identities = 69/251 (27%), Positives = 116/251 (46%), Gaps = 23/251 (9%)

Query: 54  GIVATVFGCTGFVGRYVCNKLGKIGTQL-ILPYRGDFYDAQRLKVCGDLGQVLFTPYHLL 112
           G    V G TGF+GR V N+L K G ++ ++  R + +    L     L Q+      LL
Sbjct: 3   GNKVVVLGGTGFIGRSVVNELSKSGYEISVVVRRPERFRDYMLYKNTKLVQI----DSLL 58

Query: 113 DEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGV-RRIARICREEGVERFIHLSYL 171
           D E + KA   ++VV+NL   D   K    ++  +  V ++I +     G++R + LS +
Sbjct: 59  DSEGLKKAFMGTDVVVNLTA-DLTAKTEAVSEKDIVAVNQQIKKAVESAGIKRVVALSQI 117

Query: 172 NAEEHPKPLVLKKPSAWKISKYLGEC-AVREEYPTA--TIIRASDIYGSEDRFLRSLVNK 228
            A+ +         + W  +  LGE  A+      A  TI+RA  + G  D     +  +
Sbjct: 118 GADAN------NARNNWLYN--LGESDAIMHTISCAQVTILRAGLLLGEGD----EVATR 165

Query: 229 MRSHSNLMPLYKNGLATVK-QPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287
            ++  NL P+     A+V  QP+ V D A+ +V + +D     +  + VG +R  L DL 
Sbjct: 166 FKNQLNLFPVLPVANASVAVQPLSVKDFAKALVLSIKDTTLFGKKVEVVGEERMALKDLA 225

Query: 288 DWFYKLMRKDE 298
                +M+KD+
Sbjct: 226 SLVRDMMQKDD 236


>UniRef50_Q74G63 Cluster: NADH dehydrogenase subunit, putative; n=6;
           Desulfuromonadales|Rep: NADH dehydrogenase subunit,
           putative - Geobacter sulfurreducens
          Length = 294

 Score = 64.1 bits (149), Expect = 6e-09
 Identities = 64/242 (26%), Positives = 112/242 (46%), Gaps = 23/242 (9%)

Query: 59  VFGCTGFVGRYVCNKLGKIG--TQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEES 116
           V G TGFVG +V   L + G   +L++  R +  +A   +V GD+ +           ++
Sbjct: 5   VTGGTGFVGGHVRRALLERGHSLRLLVHQRSEGVEAGIEQVEGDVTR----------PDT 54

Query: 117 IAKAVRYSNVVINLVG--RDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 174
            A AV   +  +NLVG  R++  +   +  +HV+  R +    R  G+ R + +S L   
Sbjct: 55  FAGAVAGCDATVNLVGIIREFPGRGITFEKLHVEATRNVVEAARAAGIRRHLQMSALAT- 113

Query: 175 EHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSN 234
              +P      +A+  +K+  E  VR+     TI R S I+G +  F+  L   +R    
Sbjct: 114 ---RP---DATAAYHRTKWRAEEVVRQSELDWTIFRPSLIFGPKGAFVDMLAGFVRRFP- 166

Query: 235 LMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLM 294
            +P+  +G   + QPV V DVA+    A    +T  + Y+  GP R    +++D   +++
Sbjct: 167 AVPVVGDGTYRL-QPVSVDDVARCFALALDMPETFGQTYELCGPDRLTYNEVLDIIGRVL 225

Query: 295 RK 296
            K
Sbjct: 226 GK 227


>UniRef50_Q1IZY4 Cluster: NAD-dependent epimerase/dehydratase; n=2;
           Deinococcus|Rep: NAD-dependent epimerase/dehydratase -
           Deinococcus geothermalis (strain DSM 11300)
          Length = 309

 Score = 62.5 bits (145), Expect = 2e-08
 Identities = 81/322 (25%), Positives = 132/322 (40%), Gaps = 41/322 (12%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           V G TGFVG+ +  +L   G  +    R            G L         + D  S+ 
Sbjct: 18  VTGATGFVGQALVRELVSRGHTVFAGSRSG----------GALPGATGLRLDVTDPGSVL 67

Query: 119 KAVRYSN--VVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEH 176
           +AV  ++   V++LVG   E     +  VHV+G R +      +   R++H+S L A+E 
Sbjct: 68  RAVGEADPEAVVHLVGIIQEEGTQTFRRVHVEGTRNVLAATPRQA--RYLHMSALGADE- 124

Query: 177 PKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLM 236
                    S +  SK   E  VRE     TI R S I+G  D F   ++ ++ + + ++
Sbjct: 125 ------ASASRYSASKGEAERLVRESGLAWTIFRPSLIFGVGDDFFGRVLRELVTAAPIV 178

Query: 237 PLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMRK 296
           P   +G    + PV V DVA     A    +T    Y   GP+ +        F  L+ +
Sbjct: 179 PQIGDGHFPFR-PVSVEDVALAFAGALERPETAGHTYALTGPEEFT-------FRALLEE 230

Query: 297 DEKWGGYIRYDMKYDPILPLKVALVNAISPAYPLGNLHWEGIERE----ATSDNVVIGVP 352
           ++   G  R      PI+P+ +AL+N   P   L  L    I R+      + N     P
Sbjct: 231 EQAALGQRR------PIVPVPLALMNLAVPLMQL--LPHPPITRDQYLMLKAGNTAPNEP 282

Query: 353 TLEDLGVTLTHMEDQVPWELKP 374
                G+ +  + +++P  L+P
Sbjct: 283 ARTVFGLPMHRLRERLPEILRP 304


>UniRef50_Q9HNV3 Cluster: NADH dehydrogenase/oxidoreductase-like
           protein; n=5; Halobacteriaceae|Rep: NADH
           dehydrogenase/oxidoreductase-like protein -
           Halobacterium salinarium (Halobacterium halobium)
          Length = 303

 Score = 62.1 bits (144), Expect = 2e-08
 Identities = 64/242 (26%), Positives = 102/242 (42%), Gaps = 21/242 (8%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           V G TGF+G ++C +L   G  +    R     A    V   +G V         +E++A
Sbjct: 13  VTGGTGFIGTHLCRELDDRGHDVTAFAREPADAALPADVTRIVGDVTV-------KETVA 65

Query: 119 KAVRYSNVVINLVGRDYETK----NFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 174
            A+   + V+NLV      K    + ++ DVH+ G   +     E GVE  + LS L+A+
Sbjct: 66  NAIDGHDAVVNLVALSPLFKPSGGDSRHLDVHLGGTENVVAAASEAGVEYILQLSALDAD 125

Query: 175 EHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSN 234
                     P+A+  +K   E AVR      TI+R S ++G    F+         +  
Sbjct: 126 P-------TGPTAYLRAKGRAEEAVRSSDLHHTIVRPSVVFGDGGEFVPFTKQLTTPYVT 178

Query: 235 LMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLM 294
            +P    G A+  QP++V D+   + +A   +    E Y   GP    LAD+    Y+  
Sbjct: 179 GLP---GGGASKFQPIWVGDLVPMLADALGTEAHWGETYDIGGPDVLTLADVTRMAYRAA 235

Query: 295 RK 296
            K
Sbjct: 236 GK 237


>UniRef50_Q3SGD6 Cluster: Nucleoside-diphosphate-sugar epimerases;
           n=1; Thiobacillus denitrificans ATCC 25259|Rep:
           Nucleoside-diphosphate-sugar epimerases - Thiobacillus
           denitrificans (strain ATCC 25259)
          Length = 345

 Score = 59.7 bits (138), Expect = 1e-07
 Identities = 75/273 (27%), Positives = 125/273 (45%), Gaps = 47/273 (17%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQL-ILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 117
           V G +GFVG ++ ++L   G  + +L  R +   A+ L +   + +V+    H  DE  +
Sbjct: 8   VLGGSGFVGTHLVSQLAARGLNVRVLSRRRE--TAKELILLPTV-EVVEADVH--DEHEL 62

Query: 118 AKAVRYSNVVINLVGRDYETKNFK----------YNDVHVDGVRRIARICREEGVERFIH 167
            +  R  + VINLVG  +E K  +          +  VH++  R+I     E  V R +H
Sbjct: 63  VRHFRGMDAVINLVGILHEGKVGRADLPSARRGDFQRVHIELPRKIVHAMGEANVHRLLH 122

Query: 168 LSYLNAEEHPKPLVLKKPSAWKISKYLGECAVRE------EYP---------------TA 206
           +S L A+ + +       SA++ SK +GE  VRE      E+                  
Sbjct: 123 MSALGADPNSR-------SAYQRSKGIGEALVREAGRRHVEHENWYLNGPKFIHGYGLNV 175

Query: 207 TIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDD 266
           T+ R S I+G  D FL S+  ++     ++PL  +G A    PV V DVA+   ++  + 
Sbjct: 176 TVFRPSVIFGRGDSFL-SMFARLLKRFPVLPL-GSGDARF-APVHVEDVARAFADSLDNV 232

Query: 267 DTKCEVYQAVGPKRYLLADLVDWFYKLMRKDEK 299
            T  E Y+  GP+ Y L +LV +  ++  K  +
Sbjct: 233 ATFGETYELCGPRAYTLQELVSYVGEVTGKPRR 265


>UniRef50_UPI00015BC9D3 Cluster: UPI00015BC9D3 related cluster; n=1;
           unknown|Rep: UPI00015BC9D3 UniRef100 entry - unknown
          Length = 303

 Score = 56.8 bits (131), Expect = 9e-07
 Identities = 70/240 (29%), Positives = 104/240 (43%), Gaps = 26/240 (10%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           V G TGFVG+YV   L K      L          R KV      V F      DEES+ 
Sbjct: 5   VAGGTGFVGKYVVEALEKSTHSYKL--------LTRKKVSKPHIVVDF-----FDEESLK 51

Query: 119 KAVRYS--NVVINLVGRDYE--TKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 174
           KA      +V+INL+G   E  +K   + ++H    + +  + +E G++  IH+S L   
Sbjct: 52  KAFEQEKPDVLINLIGILVEEPSKGITFENIHYLIPKNLYTVAKEYGIKHIIHMSALGVS 111

Query: 175 EHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSN 234
           E       + PS +  +K L E  +       TIIR S I G E R  + L +    + +
Sbjct: 112 E-------EAPSMYHHTKLLAEKFLMSLGIDYTIIRPSLIIGPEQRLFKDL-DFFGKYFH 163

Query: 235 LMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLM 294
           +M  +   L+    PV V DVA   V A  D + K ++ +  G K      L+   +KL+
Sbjct: 164 IM-AHPGILSYYFAPVDVRDVAFVFVKAIDDPNLKNKIIELCGKKPVSFDKLLKDSFKLL 222


>UniRef50_Q4UMY6 Cluster: Putative oxidoreductase protein; n=15;
           Rickettsia|Rep: Putative oxidoreductase protein -
           Rickettsia felis (Rickettsia azadi)
          Length = 431

 Score = 54.4 bits (125), Expect = 5e-06
 Identities = 52/232 (22%), Positives = 108/232 (46%), Gaps = 15/232 (6%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHL-LDEESI 117
           + G  GF+G Y+  +L K   ++I   R    D +  K      +V++  +++ L  +S 
Sbjct: 5   ITGANGFIGSYITAELLKNNYEVICCVR----DVESTKKKFPTAEVIYCDFNIDLTPQSW 60

Query: 118 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 177
              +   ++VIN+ G    +      +VHV+G + + + C    V+R IH+S L  ++  
Sbjct: 61  INRLNNIDIVINVSGVLASSHANNIENVHVNGPKALFKACTLTNVKRIIHISALGIDD-- 118

Query: 178 KPLVLKKPSAWKISKYLGECAVRE-EYPTATIIRASDIYGSEDRFLRSLV-NKMRSHSNL 235
                +K +A+ ++K   E  +++ E     I++ S +Y S      SL    + +    
Sbjct: 119 -----EKNTAYALTKKATEAYLQKLENIDWVILQPSLVYASGCYGGTSLFRGALATLPYF 173

Query: 236 MPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287
           +PL  +GL    QP+ + D+ + I++    +    ++ + VGP    + D++
Sbjct: 174 IPLIGDGLQQF-QPIHIDDLTKVIIHCIEREGKIHKLLKIVGPDIVTMKDIL 224


>UniRef50_Q0LC55 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Herpetosiphon aurantiacus ATCC 23779|Rep: NAD-dependent
           epimerase/dehydratase - Herpetosiphon aurantiacus ATCC
           23779
          Length = 308

 Score = 54.4 bits (125), Expect = 5e-06
 Identities = 60/248 (24%), Positives = 106/248 (42%), Gaps = 20/248 (8%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           V G TG+VG  +  KL +    + +  R     AQ+L      G V      + D ES+ 
Sbjct: 4   VTGGTGYVGSRLIEKLRQRPEPVRVLVRTP-EKAQKLVA----GNVSIVKGDVTDPESLI 58

Query: 119 KAVRYSNVVINLVGRDYETKN-FKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 177
            A++  + VI+LV    E      +  ++      +    +  GV+RF+H+S L     P
Sbjct: 59  AAMKGVSTVIHLVAIIRERSGGISFERMNYQATVNVVDAAKAAGVKRFLHMSALGVVNDP 118

Query: 178 KPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMR-----SH 232
               +   + ++  KY+    +       T+ + S I+G  D F+ +L + +R     + 
Sbjct: 119 NLPYMD--TKFRAQKYVEASGL-----DWTVFQPSVIFGEGDEFINTLADLVRRPLMIAP 171

Query: 233 SNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDW-FY 291
           +  +P+  +G  T  QPV+  DV    +    D  T  ++YQ  GP+      ++D    
Sbjct: 172 APFVPVVGDG-KTKFQPVWRDDVIDAFIKVLDDHSTIGQIYQLGGPEALTYEQMLDLIMQ 230

Query: 292 KLMRKDEK 299
           KL +K  K
Sbjct: 231 KLGKKRSK 238


>UniRef50_O54156 Cluster: Oxidoreductase; n=1; Streptomyces
           coelicolor|Rep: Oxidoreductase - Streptomyces coelicolor
          Length = 347

 Score = 53.6 bits (123), Expect = 9e-06
 Identities = 61/234 (26%), Positives = 101/234 (43%), Gaps = 23/234 (9%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           V G +GF+G ++ ++L + G ++ +  R     + R    G   QV  T   L D +S+ 
Sbjct: 18  VTGASGFIGGHLVHRLAERGHRVRVLARST---SDRAAFAGAAAQV--TVGDLGDTDSLR 72

Query: 119 KAVRYSNVVINLVGRDYETKNF-KYNDVHVDGVRRIARICREEG-VERFIHLSYLNAEEH 176
           +A      V N  G   +   + ++  V+VDG R +     E G VER +HLS  +   +
Sbjct: 73  RATTGIRHVYNCAGLSADWGPWDRFRAVNVDGARNLVEAAHEAGTVERLVHLSTTDVYGY 132

Query: 177 PKPLVLKKPSAWKI------SKYLGECAV-----REEYPTATIIRASDIYGSEDR-FLRS 224
           P+    ++ +   I      SK LGE AV     R   P  T++R   +YG   + F+  
Sbjct: 133 PERPCDERTAPRDIGLPYNRSKMLGEAAVWAAAERTGQPV-TVVRPVSVYGPGSKDFVIE 191

Query: 225 LVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGP 278
           + N +     +   Y  G       ++VS+   GI+ AA  + T    Y    P
Sbjct: 192 IANLLLGKQMV---YIRGGRVPAGLLYVSNAVDGIIAAATGEHTAGRAYNLRDP 242


>UniRef50_A0YYK8 Cluster: Oxidoreductase; n=1; Lyngbya sp. PCC
           8106|Rep: Oxidoreductase - Lyngbya sp. PCC 8106
          Length = 343

 Score = 53.2 bits (122), Expect = 1e-05
 Identities = 56/239 (23%), Positives = 107/239 (44%), Gaps = 21/239 (8%)

Query: 54  GIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLD 113
           G  A V G TGF G  +  KL + G +++   R        L+    L  + +    + D
Sbjct: 11  GSRALVTGATGFTGSLLVRKLVQQGVEVVAIAR----PTSNLEPFEGL-NIEWLRGDVFD 65

Query: 114 EESIAKAVRYSNVVINLVG--RDYETKNFKYNDVHVDGVRRIARIC-REEGVERFIHLSY 170
           E  I KA++  N + ++V   RD + K+  Y +VHV   + +A+   +E   +RF+H+S 
Sbjct: 66  ENLINKAIQGVNYIFHMVTPFRDPKLKDIGYFNVHVLSTQLLAKAALKEPNFKRFVHVST 125

Query: 171 LNAEEH------PKPLVLKKPSAWKISKYLGECAVREEYPTA----TIIRASDIYGSEDR 220
           +    H       +   +K    ++ +K   E  +R+  P A     ++R + IYG  D+
Sbjct: 126 IGVHGHIEQPPADETYRMKPGDIYQETKVEAELWIRDFAPKAGLSFAVVRPAGIYGPGDK 185

Query: 221 FLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPK 279
            L  +   +  +   +P+  +G + +   + V D+   ++ AA     + EV+    P+
Sbjct: 186 RLLKIFQMV--NKKWVPVIGDG-SNLYHFIHVDDLTNFMICAATHPKAEAEVFICGSPE 241


>UniRef50_Q67KJ4 Cluster: Putative oxidoreductase; n=1;
           Symbiobacterium thermophilum|Rep: Putative
           oxidoreductase - Symbiobacterium thermophilum
          Length = 342

 Score = 52.8 bits (121), Expect = 2e-05
 Identities = 65/238 (27%), Positives = 104/238 (43%), Gaps = 23/238 (9%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVL-FTPYHLLDEESI 117
           V G TGF+G  +   L + G Q+ +  R      +   V G L   L      L DE S+
Sbjct: 4   VTGATGFIGSQLVPHLVEQGRQVRILVRSR---QKAEAVFGPLCAALEVAEGDLGDEASL 60

Query: 118 AKAVRYSNVVINLVGR-DYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA--- 173
           A+A    + V +L  R +++    +   ++V+G RR+   C   GV+R +H+S + A   
Sbjct: 61  ARAAAGVDRVYHLASRINFQGSLRRMRAINVEGTRRLLDACAAAGVKRVVHMSSIAAGGP 120

Query: 174 ---EEHPKPLVLKK-------PSAWKISKYLGE---CAVREEYPTATIIRASDIYGSEDR 220
              +E+ +     +       P A+ I+K   E    + +E      ++R S ++G  D 
Sbjct: 121 AVKDENGRYRARTEEDEAAPLPDAYGITKLEQERLALSYQERGLEVVVVRPSAVFGPGDP 180

Query: 221 FLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGP 278
              + +  M  +  L P Y      V   VFV DV +G V AA +     EVY  VGP
Sbjct: 181 DGMNTLIWMVKNGRL-PFYLGSGQAVVNLVFVRDVVRGTV-AAMERGRPGEVYHLVGP 236


>UniRef50_Q3A8K9 Cluster: Nucleoside-diphosphate-sugar epimerases;
           n=1; Pelobacter carbinolicus DSM 2380|Rep:
           Nucleoside-diphosphate-sugar epimerases - Pelobacter
           carbinolicus (strain DSM 2380 / Gra Bd 1)
          Length = 297

 Score = 52.8 bits (121), Expect = 2e-05
 Identities = 46/184 (25%), Positives = 83/184 (45%), Gaps = 11/184 (5%)

Query: 115 ESIAKAVRYSNVVINLVG--RDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLN 172
           ES+  A+     V++LVG  R+Y  +   ++ +H      +    + + V+RF+ +S   
Sbjct: 55  ESLRGALAGCEAVVHLVGIIREYPRQKVTFDRLHRQATAHMLSAAKAQKVQRFVLMSSNG 114

Query: 173 AEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSH 232
           AE        +  S WK  + L   ++       TI R S +YG+ED F   L + +R  
Sbjct: 115 AEAEGSTAYYR--SKWKAEQLLKASSL-----DWTIFRPSVMYGAEDNFCTLLASMVRI- 166

Query: 233 SNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYK 292
             ++P++ +G   +  PV V DVA  IV +    D     +   G +     +L+D    
Sbjct: 167 LPVVPVFGDGCYRI-APVAVQDVAATIVASLARPDACGRSFACCGDQMVTFDELLDIIGG 225

Query: 293 LMRK 296
           ++R+
Sbjct: 226 VLRR 229


>UniRef50_O66532 Cluster: NADH dehydrogenase; n=2; Aquifex|Rep: NADH
           dehydrogenase - Aquifex aeolicus
          Length = 315

 Score = 52.4 bits (120), Expect = 2e-05
 Identities = 63/240 (26%), Positives = 109/240 (45%), Gaps = 22/240 (9%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           + G TGFVGR++  +L   G ++    R +    +RL   G+  QV     +  +++SI 
Sbjct: 5   ITGATGFVGRHIVRELLNRGYEVHAGVR-NLSKLERL--FGN--QVKGYIVNFDEKDSIR 59

Query: 119 KAVRYSN--VVINLVGRDYETKN--FKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 174
           +A+   N   VI+L+G  YE K     +  VH    + +  + +   V++F+ +S L   
Sbjct: 60  EALGKVNPDFVIHLIGILYEEKKKGITFERVHYGHTKNLVEVSKGFNVKKFLFMSALGTH 119

Query: 175 EHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSN 234
           +       + PS +  +K   E  V       TI R S I G E +    +  K+  +  
Sbjct: 120 D-------EAPSRYHQTKRWAEREVINSGLNYTIFRPSIILGPEQKLFFDMY-KITKYIP 171

Query: 235 LMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPK----RYLLADLVDWF 290
           ++ L   G     QPV V DVA     A ++ +T  ++Y+  G K    + LLAD+  ++
Sbjct: 172 VVALPDFGNYQF-QPVDVRDVACAYAEALKNPETDRKIYELCGTKVVTFKELLADIFSYW 230


>UniRef50_Q2S702 Cluster: Predicted nucleoside-diphosphate-sugar
           epimerase; n=1; Hahella chejuensis KCTC 2396|Rep:
           Predicted nucleoside-diphosphate-sugar epimerase -
           Hahella chejuensis (strain KCTC 2396)
          Length = 436

 Score = 51.6 bits (118), Expect = 4e-05
 Identities = 52/211 (24%), Positives = 89/211 (42%), Gaps = 16/211 (7%)

Query: 61  GCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKA 120
           G  GF+   V  KL + G Q++   R        + V   +  +     HL   E  +  
Sbjct: 7   GAGGFIASVVLEKLLEQGCQVVAVARR----RANIPVSDSVTFIQADLQHLTRMEDWSPM 62

Query: 121 VRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPL 180
           +R  + VIN  G   E++   ++ VH    + +   C + GVERF+ +S L  E+    +
Sbjct: 63  LRGVDAVINCAGILRESRKGDFDLVHFQAPKALVEACLQNGVERFVQISALGTEQDGGFI 122

Query: 181 VLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRF-LRSLVNKMRSHSNLMPLY 239
             K     K   YL         PTA ++R S +      +   SL+  + +   L+ + 
Sbjct: 123 TSKH----KFDDYL-----MRALPTAVVLRPSVVLSERGSYGGTSLLRALAALPYLLFIP 173

Query: 240 KNGLATVKQPVFVSDVAQGIVNAA-RDDDTK 269
            +G   + QP+ + D+A  +  AA R DD +
Sbjct: 174 GSGDQKI-QPILLEDLASVVAQAATRTDDAQ 203


>UniRef50_A6TJS1 Cluster: 3-beta hydroxysteroid
           dehydrogenase/isomerase; n=1; Alkaliphilus
           metalliredigens QYMF|Rep: 3-beta hydroxysteroid
           dehydrogenase/isomerase - Alkaliphilus metalliredigens
           QYMF
          Length = 286

 Score = 50.8 bits (116), Expect = 6e-05
 Identities = 61/237 (25%), Positives = 105/237 (44%), Gaps = 27/237 (11%)

Query: 61  GCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKA 120
           G TGF+G +V  ++ K G ++    R    +   L+   +L  V +    L D ESI  A
Sbjct: 6   GATGFLGGFVLEEMVKRGHKVTCFVR----ETSNLEKIKELN-VPYIFGKLDDYESICNA 60

Query: 121 VRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPL 180
           ++    +IN+    +          H      I   C+E  + R I +S          +
Sbjct: 61  LKDKETLINIASLGFG---------HAP---HIVNACQEMNINRAIFISTTG-------I 101

Query: 181 VLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGS-EDRFLRSLVNKMRSHSNLMPLY 239
             K     K  +   E  ++E     TIIR + IYG+ +DR +  LV  ++  S ++P+ 
Sbjct: 102 FTKLNPDSKGIRLEAERLIKESNLDYTIIRPTMIYGTPKDRNMWRLVQYLKKFS-VLPIL 160

Query: 240 KNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMRK 296
            NG   ++QPV+V D+A  +V+A   D +  + Y   G K     ++VD   +++ K
Sbjct: 161 GNG-TYLQQPVYVKDLAWAVVSAYETDKSIKKAYNISGLKALTYNEVVDVMGRVLGK 216


>UniRef50_Q6L130 Cluster: NADH-dependent oxidoreductase; n=2;
           Thermoplasmatales|Rep: NADH-dependent oxidoreductase -
           Picrophilus torridus
          Length = 280

 Score = 49.2 bits (112), Expect = 2e-04
 Identities = 51/204 (25%), Positives = 88/204 (43%), Gaps = 25/204 (12%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           V G +GFVGR +   L              F D + +K         + P  +   E + 
Sbjct: 5   VMGGSGFVGRNILTGLDADEKAYFSRKNSKFLDEKDIK---------YIPGDIRKPEDVE 55

Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIAR-ICREEGVERFIHLSYLNAEEHP 177
            A++  +V+++ +    E +  K+ DV V+GV+ I   I +    ++ I+ S +NAE   
Sbjct: 56  NAIKNYDVIVHAIDVLNENEE-KHEDVAVNGVKNIVNAIKKNSSGQKLIYFSAINAE--- 111

Query: 178 KPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMP 237
                K  +++  SK L E    E    + I+R S I+G  D F R L++  R +   +P
Sbjct: 112 -----KGDTSYFRSKRLAEVNA-ELLKNSLIVRPSIIFGPGDAFTRMLISAARMNPPFLP 165

Query: 238 LYKNGLATVKQPVFVSDVAQGIVN 261
              N       PV++ D+   + N
Sbjct: 166 RSGN-----MNPVYIGDLITVLKN 184


>UniRef50_Q7NW82 Cluster: Putative uncharacterized protein; n=1;
           Chromobacterium violaceum|Rep: Putative uncharacterized
           protein - Chromobacterium violaceum
          Length = 277

 Score = 48.8 bits (111), Expect = 2e-04
 Identities = 48/161 (29%), Positives = 68/161 (42%), Gaps = 12/161 (7%)

Query: 125 NVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPLVLKK 184
           + V NL G   + +   +  +H  G  R+A + R  GV R++ LS L A  H     L  
Sbjct: 52  DAVANLAGAFRQGRAGGFEAIHHAGPLRLAALARAHGVRRWVQLSALGAAAHAGAPFLS- 110

Query: 185 PSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLA 244
                 SK  G+ A+ +    A + R S IYG++    R L+   R    L+P    G  
Sbjct: 111 ------SKGRGDAALLDCGMEAVVARPSLIYGADGASSRLLLRLARLPFWLLP---EGGG 161

Query: 245 TVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLAD 285
              QPV  +DVA+G+      D     V   VG     LAD
Sbjct: 162 QRIQPVAAADVAEGLQRLIEGDAR--GVIDFVGAAEASLAD 200


>UniRef50_Q5UYL1 Cluster: UDP-glucose 4-epimerase; n=5;
           Halobacteriaceae|Rep: UDP-glucose 4-epimerase -
           Haloarcula marismortui (Halobacterium marismortui)
          Length = 334

 Score = 48.8 bits (111), Expect = 2e-04
 Identities = 59/234 (25%), Positives = 98/234 (41%), Gaps = 27/234 (11%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLI-LPYRGDFYDAQRLKVCGDLGQVL---------FTP 108
           V G  GF+G ++  +    G  ++ L  R  FYD    +   D GQ           F  
Sbjct: 11  VTGGAGFIGGHLAQRFAADGHDVVVLDNRDPFYDLDIKQHNVDAGQEAARNSDGSYEFIE 70

Query: 109 YHLLDEESIAKAVRYSNVVINLV---GRDYETKN-FKYNDVHVDGVRRIARICREEGVER 164
             + D E +   V  ++ V +     G     KN  KY++V+V+G   +   CR+EG+ER
Sbjct: 71  GDVRDAELVTDLVADADYVYHQAAQAGVRPSVKNPRKYDEVNVNGTLNLLDACRDEGIER 130

Query: 165 FIHLS---------YLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATI-IRASDI 214
           F+  S         YL  +E      +    A K++     CA  E Y  +T+ +R   +
Sbjct: 131 FVMASSSSVYGKPQYLPYDEQHPTTPVSPYGASKLAAERYACAYSEVYDLSTVALRYFTV 190

Query: 215 YGSEDRFLRSLVNKM-RSHSNLMP-LYKNGLATVKQPVFVSDVAQGIVNAARDD 266
           YG   R   ++ N + R H+   P +Y +G  T +   ++ DV    +    +D
Sbjct: 191 YGPRMRPNMAISNFVSRCHNGEPPVIYGDGTQT-RDFTYIEDVIDANMTLLHED 243


>UniRef50_A7DQP3 Cluster: 3-beta hydroxysteroid
           dehydrogenase/isomerase; n=1; Candidatus Nitrosopumilus
           maritimus SCM1|Rep: 3-beta hydroxysteroid
           dehydrogenase/isomerase - Candidatus Nitrosopumilus
           maritimus SCM1
          Length = 289

 Score = 48.8 bits (111), Expect = 2e-04
 Identities = 36/167 (21%), Positives = 78/167 (46%), Gaps = 10/167 (5%)

Query: 113 DEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLN 172
           +E+ +   ++ S  +I+LVG   ++    Y  ++V   ++I  + ++  +++ ++ S L 
Sbjct: 54  EEQLLLPKIKNSYALIHLVGIGKQSTKTDYESINVQLTQKIVNLSKKAKIKKLVYTSGLG 113

Query: 173 AEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSH 232
                  +       + ISK+  E ++ +     TI R S I G +D F + L   ++ +
Sbjct: 114 -------VFADTTMGYFISKFKAETSIIDSKIDYTIFRPSYIVGKDDLFTKYLKKSIKKN 166

Query: 233 SNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPK 279
             ++P   +G   + QP+ + DV + I  +  D   K +    VGP+
Sbjct: 167 QIIIP--GSGKYLI-QPISIGDVTKLIFQSIIDKRFKNKTLDLVGPE 210


>UniRef50_A6DZS8 Cluster: NAD-dependent epimerase/dehydratase; n=3;
           Proteobacteria|Rep: NAD-dependent epimerase/dehydratase
           - Roseovarius sp. TM1035
          Length = 319

 Score = 47.6 bits (108), Expect = 6e-04
 Identities = 44/152 (28%), Positives = 72/152 (47%), Gaps = 10/152 (6%)

Query: 111 LLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSY 170
           L D+ ++AK +  +  V+++ G+        +  V+ DGV  +A   +  GV R I +S 
Sbjct: 52  LSDKAALAKLMAGAQAVVHVAGQVRGRDLADFLGVNADGVTHVAEAAQASGVRRVILISS 111

Query: 171 LNAEE-HPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKM 229
           L A   H  P    K +     + L + A+   + T+ I+R   IYG EDR L  L   M
Sbjct: 112 LAARAPHLSPYAASKRAG---EERLAKVAIGAGF-TSAILRPPAIYGPEDRELVPLFQTM 167

Query: 230 RSHSNLMPLYKNGLATVKQPVF-VSDVAQGIV 260
                ++PL   G+A  +  +  V D+A+ IV
Sbjct: 168 A--RGIVPL--PGVAGARASLLHVDDLARAIV 195


>UniRef50_Q5NR25 Cluster: Predicted nucleoside-diphosphate-sugar
           epimerase; n=1; Zymomonas mobilis|Rep: Predicted
           nucleoside-diphosphate-sugar epimerase - Zymomonas
           mobilis
          Length = 307

 Score = 46.4 bits (105), Expect = 0.001
 Identities = 34/110 (30%), Positives = 51/110 (46%), Gaps = 7/110 (6%)

Query: 111 LLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSY 170
           L DE+S+ K V     VI++ G         +  +++ G  ++    +  G++RFIH+S 
Sbjct: 48  LEDEDSLKKLVSSCQAVIHMAGAVKAENREAFAHINLTGTEKLLAATKAAGIKRFIHVSS 107

Query: 171 LNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDR 220
           L A E        + S +  SK   E  VR      TIIR   +YGS DR
Sbjct: 108 LAARE-------AELSDYGWSKAQSEEKVRSSGLDWTIIRPPAVYGSGDR 150


>UniRef50_A2UCM7 Cluster: NAD-dependent epimerase/dehydratase; n=16;
           Gammaproteobacteria|Rep: NAD-dependent
           epimerase/dehydratase - Escherichia coli B
          Length = 304

 Score = 46.0 bits (104), Expect = 0.002
 Identities = 49/174 (28%), Positives = 82/174 (47%), Gaps = 18/174 (10%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           V G TGF+G+Y+ + L   G  +    R       R  V  +L  V  +   L D  S++
Sbjct: 7   VTGATGFIGKYIIDNLLARGFHVRALTR-----TARAHVNDNLTWVRGS---LEDTHSLS 58

Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEG-VERFIHLSYLNAEEHP 177
           + V  ++VV++  G+    K   +   +VDG  R+ +  +E G  +RF+ +S L A  HP
Sbjct: 59  ELVAGASVVVHCAGQVRGHKEEIFTRCNVDGSLRLMQAAKESGFCQRFLFISSL-AARHP 117

Query: 178 KPLVLKKPSAWKISKYLGE--CAVREEYPTATIIRASDIYGSEDRFLRSLVNKM 229
                 + S +  SKY+ E   A   +  T  + R + +YG  D+ L+ L + M
Sbjct: 118 ------ELSWYAKSKYVAEQRLAAMADEITLGVFRPTAVYGPGDKELKPLFDWM 165


>UniRef50_Q0LK91 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Herpetosiphon aurantiacus ATCC 23779|Rep: NAD-dependent
           epimerase/dehydratase - Herpetosiphon aurantiacus ATCC
           23779
          Length = 286

 Score = 45.6 bits (103), Expect = 0.002
 Identities = 51/229 (22%), Positives = 101/229 (44%), Gaps = 19/229 (8%)

Query: 61  GCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKA 120
           G +GF+GR+V  +L + G QL    R      +         Q +   +  L   +    
Sbjct: 7   GASGFIGRHVAEELHQAGHQLTCLVR-----QKPTTPINSATQYVAAEW--LKPTTWLDQ 59

Query: 121 VRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPL 180
           +   ++VIN VG   E++   +  VH      + +   + G+++ I +S L A+      
Sbjct: 60  LAEHDMVINCVGMLRESRQASFQAVHTSVPIALFKAAAQYGLQKIIQISALGAD------ 113

Query: 181 VLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYK 240
            +  P A+  SK L + A+ ++     ++R S +YG+   +   L  ++ +   + P+  
Sbjct: 114 -VAAPQAFVRSKALADQALSQQSVPWVVLRPSFVYGA-GCYSMELFRRL-ARLPITPILG 170

Query: 241 NGLATVKQPVFVSDVAQGIVNAARDDD-TKCEVYQAVGPKRYLLADLVD 288
           +G   V QP+ + D+ + I  A  D   T C + +A G ++     L++
Sbjct: 171 DGSYQV-QPIQIGDLVRAIRQAVEDPTITNC-LIEAGGSEQLSFRQLLE 217


>UniRef50_A1WAD5 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Acidovorax sp. JS42|Rep: NAD-dependent
           epimerase/dehydratase - Acidovorax sp. (strain JS42)
          Length = 328

 Score = 45.6 bits (103), Expect = 0.002
 Identities = 47/167 (28%), Positives = 79/167 (47%), Gaps = 14/167 (8%)

Query: 56  VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 115
           +  V G TGF+GR++   L + G ++ L  R +   A+  +   ++         L +E 
Sbjct: 17  LVAVTGATGFIGRHLIAALVQAGWRVRLLLRREPSGAEWRQSTPEV-----VAGSLDNEA 71

Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVE-RFIHLSYLNAE 174
           ++A+ V   + VI+L G     +   +  V+  GV RIAR  ++   +  F+ +S L A 
Sbjct: 72  AVARLVEGVDAVIHLAGLIKAARRADFFAVNEQGVARIARATKQLSPDAHFLLVSSLAAR 131

Query: 175 EHPKPLVLKKPSAWKISKYLGECAVREEY-PTATIIRASDIYGSEDR 220
           E   PL+    S +  SK  GE A  +     AT++R   +YG  DR
Sbjct: 132 E---PLL----SDYAASKRAGEAAALDAMGARATVLRPPAVYGPGDR 171


>UniRef50_A7H7V8 Cluster: NAD-dependent epimerase/dehydratase; n=2;
           Deltaproteobacteria|Rep: NAD-dependent
           epimerase/dehydratase - Anaeromyxobacter sp. Fw109-5
          Length = 304

 Score = 45.2 bits (102), Expect = 0.003
 Identities = 43/152 (28%), Positives = 71/152 (46%), Gaps = 18/152 (11%)

Query: 147 VDGVRRIARICREEGVERFIHLSYLN-AEEHPKPLVLKKPSAWKISKYLGECAVREEYPT 205
           V+  R + R   E GVER +H+S  N A + P P    K    ++ + LGE  +     +
Sbjct: 90  VENSRALFRAAAEAGVERVVHVSITNPAPDSPLPYFRGKA---EVERALGESGL-----S 141

Query: 206 ATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVK-QPVFVSDVAQ-GIVNAA 263
             I+R +  +G  D  + ++   +R     +PL+     T   QPV V D+A+  + +A 
Sbjct: 142 HAILRPAVFFGGRDVLINNIAWLLRR----LPLFGVASGTYGIQPVHVEDLARLAVEHAE 197

Query: 264 RDDDTKCEVYQAVGPKRYLLADLVDWFYKLMR 295
           R  D    V  AVGP+ +   +LV    + +R
Sbjct: 198 RGADV---VLDAVGPEAFAFDELVGLVRRAVR 226


>UniRef50_A7CTR2 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Opitutaceae bacterium TAV2|Rep: NAD-dependent
           epimerase/dehydratase - Opitutaceae bacterium TAV2
          Length = 306

 Score = 45.2 bits (102), Expect = 0.003
 Identities = 45/186 (24%), Positives = 80/186 (43%), Gaps = 12/186 (6%)

Query: 102 GQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEG 161
           G+V   P    D +++A+     +V+ N     ++   F +    V   R +    R  G
Sbjct: 49  GRVQAHPLDFRDPDALARHFENVDVLHNTYWVRFDHARFTHEQA-VANTRILFDAARRAG 107

Query: 162 VERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRF 221
           V R +H+S  N +       ++ P  +   K   E A+ E     TI+R + ++G     
Sbjct: 108 VRRIVHVSITNPD-------IQSPLPYFRGKAQVEQALAESGIPHTILRPAVLFGDTAIL 160

Query: 222 LRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRY 281
           L ++   +R    L  ++ +G   + QP+ V D+A   V+AA   D  C    A GP+ +
Sbjct: 161 LNNIAWMLRRFP-LFGVFGDGHYKL-QPIHVEDLADLAVHAAFATDNHC--LDATGPETF 216

Query: 282 LLADLV 287
              +LV
Sbjct: 217 TYIELV 222


>UniRef50_A1VGT7 Cluster: NAD-dependent epimerase/dehydratase; n=2;
           Desulfovibrio vulgaris subsp. vulgaris|Rep:
           NAD-dependent epimerase/dehydratase - Desulfovibrio
           vulgaris subsp. vulgaris (strain DP4)
          Length = 304

 Score = 45.2 bits (102), Expect = 0.003
 Identities = 37/118 (31%), Positives = 61/118 (51%), Gaps = 12/118 (10%)

Query: 58  TVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 117
           T+FG  GF+G +VC+KL + G  + +    D   +  L+      Q + T  ++LDEE +
Sbjct: 4   TLFGGAGFLGSHVCDKLSEAGHDVTVV---DLRPSPYLRP----DQTMITG-NILDEELV 55

Query: 118 AKAVRYSNVVINLVG-RDYETKNFKYND---VHVDGVRRIARICREEGVERFIHLSYL 171
           A+AV  +++V N  G  D    N +  D   ++V G       CR+ GV+R++  S L
Sbjct: 56  ARAVEGADMVFNYAGIADIGEANRRPVDTARINVLGNVIALEACRKAGVKRYVFASSL 113


>UniRef50_A0RYZ0 Cluster: Nucleoside-diphosphate-sugar epimerase;
           n=1; Cenarchaeum symbiosum|Rep:
           Nucleoside-diphosphate-sugar epimerase - Cenarchaeum
           symbiosum
          Length = 249

 Score = 45.2 bits (102), Expect = 0.003
 Identities = 37/129 (28%), Positives = 57/129 (44%), Gaps = 10/129 (7%)

Query: 151 RRIARICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIR 210
           R I ++CR  G+ R  +LS L A            SA  +S+Y  E  +       TI R
Sbjct: 54  RDIVKLCRTAGIGRITYLSGLGASP-------SSTSAHFLSRYAAEQEIASSGLEYTIFR 106

Query: 211 ASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKC 270
            S I G+ DR  R L  +++    ++P   +G   V QP+ + D  + I ++A  D    
Sbjct: 107 PSFILGTADRLTRGLKKQLKEGGAVIP--GSGEYPV-QPIHIDDACRIIRDSAISDAYLN 163

Query: 271 EVYQAVGPK 279
                VGP+
Sbjct: 164 STVDLVGPR 172


>UniRef50_Q89WS9 Cluster: Bll0599 protein; n=1; Bradyrhizobium
           japonicum|Rep: Bll0599 protein - Bradyrhizobium
           japonicum
          Length = 272

 Score = 44.4 bits (100), Expect = 0.005
 Identities = 61/229 (26%), Positives = 92/229 (40%), Gaps = 21/229 (9%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           V G TG +GR + ++L + G  + +  R            GDL         L D +++ 
Sbjct: 6   VTGGTGHLGRDIVDRLVRSGRHVRVLARSPGTRPDVEWAIGDLATGAGLRDALHDVDTVI 65

Query: 119 KAVRYSNVVINLVGRDYETKNFKY-NDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 177
            A  YS +     G    T  F   + V V+G  R+   C E  V  F+H+S +  +E  
Sbjct: 66  NAATYSPIARR--GGIRPTDFFTSPSAVDVEGTARLLSSCGEARVRHFLHVSIVGLDEAT 123

Query: 178 KPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMP 237
            P        +   K  GE  VR    + +++RA   Y   DR L  L          +P
Sbjct: 124 LP--------YARVKLAGERLVRASALSWSVVRAMPFYYLLDRLLSGLA--------WLP 167

Query: 238 LYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADL 286
           ++     T+  PV  SDVA  +V A   D T+ E  +  GP+   L  L
Sbjct: 168 VWPVP-TTLFNPVDTSDVADHVV-ACAFDGTRGERAEIGGPEDIELVSL 214


>UniRef50_Q1YFT6 Cluster: Possible NAD-dependent
           epimerase/dehydratase; n=1; Aurantimonas sp.
           SI85-9A1|Rep: Possible NAD-dependent
           epimerase/dehydratase - Aurantimonas sp. SI85-9A1
          Length = 308

 Score = 44.0 bits (99), Expect = 0.007
 Identities = 61/233 (26%), Positives = 95/233 (40%), Gaps = 29/233 (12%)

Query: 61  GCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFT-PYHLLDEESIAK 119
           G +GFVGR++   L   G  +++  RG           G  G  +F  P +L D E+   
Sbjct: 7   GSSGFVGRHLKAALAADGHDIVVLRRG-----------GPGGDGVFAAPANLADIETTPD 55

Query: 120 AVRYSNVVINLVGRDYETKNFKYND------VHVDGVRRIARICREEGVERFIHLSYLNA 173
             R  + V +L   +         D      V+ DG   +AR   +EGV R + +S  N 
Sbjct: 56  WPRGIDAVAHLAAANPGRGTADAADLAALAAVNRDGTAALARRAAQEGVRRMVFVSTANV 115

Query: 174 EE-HPKPLVLKKP----SAWKISKYLGECAVRE----EYPTATIIRASDIYGSEDRFLRS 224
               P P+    P    SA+  SK+ GE A  +       T  ++R   ++G   R   +
Sbjct: 116 HAAFPDPVDEASPIAPQSAYARSKHEGERAFWQGLSGSATTGCVLRPVPVFGPGGRGGIA 175

Query: 225 LVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVG 277
            + K+      +PL   GLA  +  V V D+ Q IV A   +    E++   G
Sbjct: 176 ALAKLARMPAPLPL--GGLAAPRSLVAVDDLVQAIVLALTAEQAAGEIFLVAG 226


>UniRef50_A3WA10 Cluster: Predicted nucleoside-diphosphate-sugar
           epimerase; n=4; Sphingomonadales|Rep: Predicted
           nucleoside-diphosphate-sugar epimerase - Erythrobacter
           sp. NAP1
          Length = 304

 Score = 44.0 bits (99), Expect = 0.007
 Identities = 47/205 (22%), Positives = 87/205 (42%), Gaps = 21/205 (10%)

Query: 56  VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 115
           +  + G TGFVG+   +   + G  +    R D    +R         V + P  L   E
Sbjct: 3   IVAITGATGFVGKATLDVAVQKGLHVRALTRRDAQPRER---------VTWVPGTLDRAE 53

Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 175
           ++ + V   + VI++ G        ++   +V G   +    + +G+ERF+ +S L+A E
Sbjct: 54  ALEELVSGCDAVIHVAGLTSTPNPGRFEAANVTGTANMIAAAKSQGIERFVFVSSLSARE 113

Query: 176 HPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNL 235
                     SA+  SK   E  V +     TI+R   +YG  D+    L    +    +
Sbjct: 114 -------PDLSAYGASKAKAERLVEDSGLDWTIVRPPGVYGPGDKDYLDLFKAAK--LGI 164

Query: 236 MPLYKNGLATVKQPVFVSDVAQGIV 260
           +P+   G +++   + V D+A+ +V
Sbjct: 165 VPVPPEGKSSL---IHVEDLARLLV 186


>UniRef50_A1ASP8 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Pelobacter propionicus DSM 2379|Rep: NAD-dependent
           epimerase/dehydratase - Pelobacter propionicus (strain
           DSM 2379)
          Length = 318

 Score = 43.6 bits (98), Expect = 0.009
 Identities = 54/210 (25%), Positives = 88/210 (41%), Gaps = 18/210 (8%)

Query: 54  GIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLD 113
           G+   + G TGFVG  +  +L +   ++    R        L  C +   + +    L D
Sbjct: 13  GLTVALTGGTGFVGGAIIRRLLEDRVRVRALVR-----PASLASCFEAKGLTWIHGELGD 67

Query: 114 EESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREE-GVERFIHLSYLN 172
            ES+ + V  ++ VI+  G         +   +V GV RI    RE  G  R +  S L 
Sbjct: 68  RESLRRLVEGASAVIHCAGSVRGACPADFEPANVSGVERIVAAARESAGHPRLLLFSSLA 127

Query: 173 AEEHPKPLVLKKPSAWKISKYLGECAVREEYPTA--TIIRASDIYGSEDRFLRSLVNKMR 230
           A          + S +  SK  GE A+R        TI+R   +YG  DR +  L+  MR
Sbjct: 128 ARS-------PELSDYAASKRRGEDALRSAAQGLDWTILRPPAVYGPGDREMLPLLQWMR 180

Query: 231 SHSNLMPLYKNGLATVKQPVFVSDVAQGIV 260
                +P    G  ++   ++VSD+A+ ++
Sbjct: 181 RGILFVPGSGAGRLSL---IYVSDLAEAVL 207


>UniRef50_A3YG10 Cluster: Putative uncharacterized protein; n=1;
           Marinomonas sp. MED121|Rep: Putative uncharacterized
           protein - Marinomonas sp. MED121
          Length = 306

 Score = 43.2 bits (97), Expect = 0.012
 Identities = 39/145 (26%), Positives = 64/145 (44%), Gaps = 11/145 (7%)

Query: 61  GCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCG-DLGQVLFTPYHLLDEESIAK 119
           G TG++GRY+  +L K     I   R      ++L+  G +  Q+      + D  S+A 
Sbjct: 9   GATGYLGRYLVQRLLKQNGPFIAMGRS----IKKLESMGLETQQIRLA--QVTDPISLAG 62

Query: 120 AVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP-- 177
                +VVI+ VG   +     Y DV       +       GV++FI++S  NA  H   
Sbjct: 63  CCHGIDVVISCVGITRQKDGLNYMDVDYQANINLLEEAERSGVKKFIYISAFNAPNHQSV 122

Query: 178 KPLVLKKPSAWKI--SKYLGECAVR 200
           + L  K+  A ++  S+ L  C +R
Sbjct: 123 RMLYAKEQFAQRLLSSQMLAPCVIR 147


>UniRef50_Q8KDL0 Cluster: 3-beta hydroxysteroid
           dehydrogenase/isomerase family protein; n=10;
           Chlorobiaceae|Rep: 3-beta hydroxysteroid
           dehydrogenase/isomerase family protein - Chlorobium
           tepidum
          Length = 331

 Score = 42.3 bits (95), Expect = 0.022
 Identities = 31/117 (26%), Positives = 54/117 (46%), Gaps = 5/117 (4%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           V G TGF+G  + ++L   G  + +  R    D   LK C  L ++      + D  S++
Sbjct: 7   VTGGTGFIGSRLVHRLAASGEDVYVLVRASS-DLASLKEC--LDRITLVYGDVTDIASLS 63

Query: 119 KAVRYSNVVINLVGRDY--ETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA 173
            A   +  V +  G  Y  + KN     ++V+G + +   CR   V+R +H+S + A
Sbjct: 64  GAFEGAEEVYHCAGITYMGDRKNPLLQRINVEGTQNVLDACRRAKVKRVVHVSSITA 120


>UniRef50_A2C1Q9 Cluster: Putative uncharacterized protein; n=1;
           Prochlorococcus marinus str. NATL1A|Rep: Putative
           uncharacterized protein - Prochlorococcus marinus
           (strain NATL1A)
          Length = 299

 Score = 42.3 bits (95), Expect = 0.022
 Identities = 29/91 (31%), Positives = 47/91 (51%), Gaps = 3/91 (3%)

Query: 207 TIIRASDIYGS-EDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARD 265
           TIIR + IYGS +DR +  L+ K   +  ++P++ NG  +++QPV V DVA  +V     
Sbjct: 136 TIIRPTMIYGSPKDRNMIKLI-KWIDNMPIIPIFGNG-KSLQQPVNVKDVAWSLVKIIDK 193

Query: 266 DDTKCEVYQAVGPKRYLLADLVDWFYKLMRK 296
             T    +   G +      +VD   K++ K
Sbjct: 194 KSTYYRSFNISGKEPLTFTQIVDIIEKMLNK 224


>UniRef50_Q2W798 Cluster: DTDP-6-deoxy-L-mannose-dehydrogenase; n=2;
           Magnetospirillum|Rep:
           DTDP-6-deoxy-L-mannose-dehydrogenase - Magnetospirillum
           magneticum (strain AMB-1 / ATCC 700264)
          Length = 296

 Score = 41.5 bits (93), Expect = 0.038
 Identities = 34/103 (33%), Positives = 50/103 (48%), Gaps = 8/103 (7%)

Query: 136 ETKNFKYNDVHVDGVRRIARICREEGVERFIHLS--YLNAEEHPKPLVLKKP----SAWK 189
           ET+      ++ +G   +AR C   G+   IHLS  Y+     P+P     P    S + 
Sbjct: 68  ETETAAAMAINGEGPAHLARACAARGIP-LIHLSTDYVFDGRSPEPYREDAPMAPLSVYG 126

Query: 190 ISKYLGECAVREEYPTATIIRASDIYGSE-DRFLRSLVNKMRS 231
            SK  GE AVR   P   I+R S +YG E   F+R++V  +R+
Sbjct: 127 ASKAAGEEAVRWLQPDHAILRVSWLYGGERGDFVRAMVGAIRA 169


>UniRef50_Q2RKH0 Cluster: NAD-dependent epimerase/dehydratase; n=2;
           Firmicutes|Rep: NAD-dependent epimerase/dehydratase -
           Moorella thermoacetica (strain ATCC 39073)
          Length = 323

 Score = 41.5 bits (93), Expect = 0.038
 Identities = 65/258 (25%), Positives = 111/258 (43%), Gaps = 28/258 (10%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQL--ILPY--RGDFYDAQRLKVCGDLGQVLFTPYHLLDE 114
           V G  GF+G ++  KL + G ++   + Y  R  +   +  +V  D+   +FT   + D 
Sbjct: 5   VTGAGGFIGSHLTEKLVREGHKVRAFVHYNSRNTWGWLEESEVKDDIE--VFTG-DIRDY 61

Query: 115 ESIAKAVRYSNVVINL---VGRDYE-TKNFKYNDVHVDGVRRIARICREEGVERFIHLS- 169
           +S+  ++R   VV +L   +G  Y       Y   +V+G   I +  REEG+ R +H S 
Sbjct: 62  DSVRASLRGIEVVFHLAALIGIPYSYVTPVAYIKTNVEGTYNICQAAREEGLRRVVHTST 121

Query: 170 --------YLNAEEHPKPLVLKKP-SAWKI-SKYLGECAVREEYPTATIIRASDIYG--- 216
                   Y+  +E+  PL  + P +A KI +  L     R      TIIR  + YG   
Sbjct: 122 SEVYGTARYVPIDEN-HPLQAQSPYAASKIGADQLALSFYRSFDLPVTIIRPFNTYGPRQ 180

Query: 217 SEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAV 276
           S    + +++ ++ S    + L    LA  +   FV D   G + A     T  EV    
Sbjct: 181 SARAVIPTIITQLLSGREEIRL--GNLAPTRDFNFVEDTVNGFITAGLSPHTVGEVVNIG 238

Query: 277 GPKRYLLADLVDWFYKLM 294
             +   + +LV+   +L+
Sbjct: 239 SGREISIGELVELIGQLI 256


>UniRef50_Q1LGK6 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Ralstonia metallidurans CH34|Rep: NAD-dependent
           epimerase/dehydratase - Ralstonia metallidurans (strain
           CH34 / ATCC 43123 / DSM 2839)
          Length = 430

 Score = 41.5 bits (93), Expect = 0.038
 Identities = 58/237 (24%), Positives = 96/237 (40%), Gaps = 21/237 (8%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           V G +G +G  +C +L   G ++I   RG         V  D G    T   +   E   
Sbjct: 11  VCGASGLIGAVLCKRLEAQGHEVI---RGVRTPTSARDVAMDFG----TDTTI---EQWL 60

Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 178
             V+  +VVIN VG   ET   ++  VH      + R C + GV R I +S L A+    
Sbjct: 61  PRVQGMHVVINAVGIIVETGTNRFEAVHHLAPAALFRACAKAGVGRVIQISALGADRGDT 120

Query: 179 PLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPL 238
           P    K  A  + + L    V+ +    +++ A D  G      R+L +       ++P+
Sbjct: 121 PYFRSKRGADDVLRAL---PVQWQVLYPSLVYAQD--GDSAAMFRTLAS-----LPVIPV 170

Query: 239 YKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLMR 295
            + G A   QPV + D+   +V          +  + VG  R     ++D + + M+
Sbjct: 171 PELGDARF-QPVHIDDLVDTVVTVIVPAIPPGQCIEVVGASRMSYRAMLDTYRQGMQ 226


>UniRef50_A7BY73 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Beggiatoa sp. PS|Rep: NAD-dependent
           epimerase/dehydratase - Beggiatoa sp. PS
          Length = 308

 Score = 41.5 bits (93), Expect = 0.038
 Identities = 51/229 (22%), Positives = 102/229 (44%), Gaps = 17/229 (7%)

Query: 61  GCTGFVGRYVCNKLGKIGTQLILPYRG-DFYDAQRLKVCGDLGQVLFTPYHLLDEESI-A 118
           G +GF+G+++ + L   G Q++   R  + + A+  +V     + L   Y    E  I  
Sbjct: 7   GASGFIGQHLLSALMAKGYQIVACVRQPNQWQARFPEV-----KWLACDYAKDHEPHIWL 61

Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 178
             +   +VVIN VG   ET+  ++ D+H      + +   + G+ + + +S L A+E   
Sbjct: 62  PRLEQIDVVINAVGIIRETRGQRFEDLHTHAPIALFKAAEQLGIRKILQISALGADE--- 118

Query: 179 PLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPL 238
               K  SA+ +SK   + A+      A II+ S + G       S +    +   ++P+
Sbjct: 119 ----KAESAYHLSKRAADEALLTLTVDAMIIQPSIVIGRGGG--SSTLFSAMAALPVIPV 172

Query: 239 YKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287
             +G   + QP+ + D+   ++   R+  +  +  + VG +R     L+
Sbjct: 173 IGSGEQPI-QPIAIEDLTACVLALLRNWPSSNQRIELVGAQRMTFLQLL 220


>UniRef50_Q12VM5 Cluster: NAD-dependent epimerase/dehydratase; n=2;
           cellular organisms|Rep: NAD-dependent
           epimerase/dehydratase - Methanococcoides burtonii
           (strain DSM 6242)
          Length = 294

 Score = 41.5 bits (93), Expect = 0.038
 Identities = 60/242 (24%), Positives = 105/242 (43%), Gaps = 31/242 (12%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           VFG  GF+G Y+  +L       +  Y     D    K    + + +F   ++LD+  +A
Sbjct: 7   VFGGCGFLGSYLVERL------CMKKYEVTVADLNLSKY---INKDIFVECNILDKIKVA 57

Query: 119 KAVRYSNVVINLVGRDYETKNFKYN----DVHVDGVRRIARICREEGVERFIHLSYLNAE 174
           + V+ +++V N  G     K  +      +++V G   I   C + GVERF++ S   + 
Sbjct: 58  ELVKNADIVYNFAGMANLDKAVEDPCGTIELNVIGNLNILDACMQSGVERFVYASSAYS- 116

Query: 175 EHPKPLVLKKPSAWKISKYLGECAVREEYPTA-----TIIRASDIYG---SEDRFLRSLV 226
                 +  K S + ISK   E  + EEY        TIIR   +Y    SE+ ++ +L+
Sbjct: 117 ------MSDKGSFYGISKLTSEKLI-EEYNAKYDLKYTIIRYGSVYSERISENNYIYNLL 169

Query: 227 NKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADL 286
            K    S  +  + +G   +++ +  SDVAQ  V     +  + E     G +R    +L
Sbjct: 170 -KNAIISGKIKHFGDG-EEIREYIHASDVAQLSVEIIESNQFENEHIILTGMERMKRKEL 227

Query: 287 VD 288
            +
Sbjct: 228 FE 229


>UniRef50_Q0C1U1 Cluster: Putative UDP-glucose 4-epimerase; n=1;
           Hyphomonas neptunium ATCC 15444|Rep: Putative
           UDP-glucose 4-epimerase - Hyphomonas neptunium (strain
           ATCC 15444)
          Length = 330

 Score = 41.1 bits (92), Expect = 0.050
 Identities = 46/171 (26%), Positives = 75/171 (43%), Gaps = 14/171 (8%)

Query: 61  GCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKA 120
           G TGFVGR    +L +  TQ  +P R      Q  +   D   + +    L  + +++  
Sbjct: 11  GATGFVGR----QLLRDRTQNSVPVRA-LARMQPHRKLTDGNGIEWISGDLSSDAALSSL 65

Query: 121 VRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPL 180
           V  +++VI+L G         + +V+      + R  +  GV+ F+H+S L A    +P 
Sbjct: 66  VSNADIVIHLAGATKARNASVFREVNALRTAELVRRAQAAGVQHFVHVSSLTAS---RPD 122

Query: 181 VLKKPSAWKISKYLGECAVREEYPT--ATIIRASDIYGSEDRFLRSLVNKM 229
           +    SA+  SK   E    E   +   TI+RA  I G  D   RSL + +
Sbjct: 123 I----SAYAKSKAESEILAAENAGSMALTIVRAPAILGPGDDATRSLFSAL 169


>UniRef50_Q0ANG5 Cluster: NAD-dependent epimerase/dehydratase
           precursor; n=1; Maricaulis maris MCS10|Rep:
           NAD-dependent epimerase/dehydratase precursor -
           Maricaulis maris (strain MCS10)
          Length = 431

 Score = 41.1 bits (92), Expect = 0.050
 Identities = 39/163 (23%), Positives = 64/163 (39%), Gaps = 9/163 (5%)

Query: 125 NVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPLVLKK 184
           +VVIN VG   +        VHVDG   + + C + GV R +H+S +  +          
Sbjct: 67  DVVINCVGVLQDGLGDSSRKVHVDGAMALFKACEQAGVGRVLHISAVGVD-------TAA 119

Query: 185 PSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLA 244
            S +   K  GE A+        I+R S +         +LV  +     + P+   G  
Sbjct: 120 GSDYARDKLAGEAALAARDLDWLILRPSLVVARNVYGGTALVRSLCGIPFVTPVV--GGE 177

Query: 245 TVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287
            V +P+ + D+ + +             +   GP+R  LAD V
Sbjct: 178 QVFRPIGMDDLCEAVAGLIEPGAPARTSFDLAGPERVSLADTV 220


>UniRef50_A3ZLP8 Cluster: NAD-dependent epimerase/dehydratase family
           protein/3- betahydroxysteroid dehydrogenase/isomerase
           family protein; n=1; Blastopirellula marina DSM
           3645|Rep: NAD-dependent epimerase/dehydratase family
           protein/3- betahydroxysteroid dehydrogenase/isomerase
           family protein - Blastopirellula marina DSM 3645
          Length = 339

 Score = 41.1 bits (92), Expect = 0.050
 Identities = 50/173 (28%), Positives = 72/173 (41%), Gaps = 17/173 (9%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           V G TGF+GRY+C +L   G  L    R         +    LG V      L +   + 
Sbjct: 6   VTGATGFIGRYLCRRLVADGHSLRCAVR----QTSATEPLEQLG-VELVEVDLSNPHDLE 60

Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIAR-ICREEGVERFIHLSYLNA---- 173
           +A+     + ++ G    T   K   V+ DG RRI      +      +++S L A    
Sbjct: 61  QAIEGCEAIFHVAGLICATAPEKLFHVNRDGTRRIVEAAAAQTNPPTVLYISSLAAVGPS 120

Query: 174 -EEHPK-PLVLKKP-SAWKISKYLGEC---AVREEYPTATIIRASDIYGSEDR 220
             EH K P    KP S +  SK  GE     V +  P  TI+R S ++G E+R
Sbjct: 121 RTEHKKRPDHFPKPVSNYGRSKRAGERQAELVADRVP-ITIVRPSIVFGGENR 172


>UniRef50_A0NYC5 Cluster: DTDP-glucose 4,6-dehydratase; n=1; Stappia
           aggregata IAM 12614|Rep: DTDP-glucose 4,6-dehydratase -
           Stappia aggregata IAM 12614
          Length = 348

 Score = 40.7 bits (91), Expect = 0.066
 Identities = 34/126 (26%), Positives = 56/126 (44%), Gaps = 9/126 (7%)

Query: 51  SFNGIVATVFGCTGFVGRYVCNKLGK---IGTQLILPYRGDFYDAQRLKVCGDLGQVLFT 107
           SF  IV T  G  GF+G  V  ++ +   +   +IL       D +RL   GD G +   
Sbjct: 29  SFRKIVVT--GGLGFIGSKVFKRVARMANVAETVILDRVSYAADFRRLAPVGDAGDLPVI 86

Query: 108 PYHLLDEESIAKAVRYSNVVINLVGRDYETKNFK----YNDVHVDGVRRIARICREEGVE 163
              +     +A A+   + VI+L    +  ++F     + DV+V G   +     + GV+
Sbjct: 87  RGDIRSPIDVAAALHDCDAVIHLAAETHVPRSFTAPELFFDVNVTGTEVLLNAALDAGVK 146

Query: 164 RFIHLS 169
            FIH+S
Sbjct: 147 HFIHIS 152


>UniRef50_Q0S7J3 Cluster: Reductase; n=2; Nocardiaceae|Rep:
           Reductase - Rhodococcus sp. (strain RHA1)
          Length = 336

 Score = 39.9 bits (89), Expect = 0.12
 Identities = 61/227 (26%), Positives = 94/227 (41%), Gaps = 29/227 (12%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           V G  GFVG  + N L + G ++         D  R +   + G V +    +LD ES+ 
Sbjct: 5   VTGAAGFVGNNLLNLLVEAGHEVTA------IDRVRSRYAPEYG-VTWVNADVLDVESMK 57

Query: 119 KAVRYSNVVINLVGR-DYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA---- 173
           +A+  + VV +LV       K+     V+  GVR +A      GV R +H S +++    
Sbjct: 58  RALEGAEVVYHLVAMITLAQKDDLAWTVNTKGVRTVAEAALAVGVRRMVHCSSVHSFDQS 117

Query: 174 -------EEHPKPLVLKKPSAWKISKYLGECAVREEYPT---ATIIRASDIYGSEDRFLR 223
                  E  P+ +    P  +  SK+ GE  +RE       A I   + +YG  D  L 
Sbjct: 118 SCGGTLDENSPRSVDASIP-VYDRSKWAGEIELREVVEAGLDAVICNPTGVYGPVDYGL- 175

Query: 224 SLVNKMRSHS--NLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDT 268
           S VN +  ++    +P    G       V V DVA G++ A     T
Sbjct: 176 SRVNALLRNAARGRVPAAVQGGFDF---VDVRDVAAGLIAAGEKGRT 219


>UniRef50_Q0DWQ7 Cluster: Cyclin-B1-2; n=6; Oryza sativa|Rep:
           Cyclin-B1-2 - Oryza sativa subsp. japonica (Rice)
          Length = 391

 Score = 39.9 bits (89), Expect = 0.12
 Identities = 23/58 (39%), Positives = 33/58 (56%), Gaps = 4/58 (6%)

Query: 248 QPVFVSDVAQGIVNAARDDDTKC-EVYQAVGPKRYLLADLVDWFYKLMRKDEKWGGYI 304
           QPV+V DVA  IVN+ +DD T   + Y   GP+ Y + DL +  Y+ +    +W  YI
Sbjct: 322 QPVYVVDVAAAIVNSLKDDGTSMGKSYGLGGPEIYTVHDLAELMYETIC---EWPRYI 376


>UniRef50_Q5ZVY7 Cluster: Oxidoreductase; n=4; Legionella
           pneumophila|Rep: Oxidoreductase - Legionella pneumophila
           subsp. pneumophila (strain Philadelphia 1 /ATCC 33152 /
           DSM 7513)
          Length = 432

 Score = 39.5 bits (88), Expect = 0.15
 Identities = 54/230 (23%), Positives = 94/230 (40%), Gaps = 14/230 (6%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPY-HLLDEESI 117
           V G +GF+       L   G ++I   R   +  QR+   G   QV+F  + +    E  
Sbjct: 5   VTGASGFIASQFVTDLLIAGHEIICCVRNTKH-TQRI-FPG--AQVIFCDFINDTKPEIW 60

Query: 118 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 177
           +K ++  +VVIN VG  Y        +VH +  + +   C   GV++ I +S L  ++  
Sbjct: 61  SKRLQGIDVVINCVGILYHPDERIIWNVHYETPKALFDACINSGVKKIIQISALGIDKVD 120

Query: 178 KPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMP 237
                 K +   I  YL   ++      + I+R S +YG       SL   +        
Sbjct: 121 VSYATSKKA---IDDYLLTLSI-----PSVIVRPSYVYGKGSYGGSSLFRGIAGTPFFTA 172

Query: 238 LYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287
           +   G     QP+ ++D++Q IV       T+  +  AV  K   L +++
Sbjct: 173 IPGQGTQKF-QPISLNDLSQAIVRLVSTPVTETIILHAVSKKIITLEEII 221


>UniRef50_A0A018 Cluster: MoeS5; n=4; Actinomycetales|Rep: MoeS5 -
           Streptomyces ghanaensis
          Length = 282

 Score = 39.5 bits (88), Expect = 0.15
 Identities = 38/139 (27%), Positives = 58/139 (41%), Gaps = 11/139 (7%)

Query: 145 VHVDGVRRIARICREEGVERFIHLS----YLNAEEHPKPLVLKKP-SAWKISKYLGECAV 199
           V  DG  R+A      G  R +H+S    +  A+ H     L  P S +  +K   E AV
Sbjct: 78  VTADGAARLALEAARAGC-RLVHVSSDAVFSGADVHYPEEALPDPVSPYGAAKAAAETAV 136

Query: 200 REEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGI 259
           R   P A ++R S I G         V+ + +      L+ +    V+ PV V D+A  +
Sbjct: 137 RVAVPEAAVVRTSLIVGHNRSAHEEAVHALAAGRRAGVLFTD---DVRCPVHVDDLASAL 193

Query: 260 VNAARDDDTKCEVYQAVGP 278
           +  A  D +   V+   GP
Sbjct: 194 LEIAASDGS--GVFHVAGP 210


>UniRef50_Q5V0D3 Cluster: DTDP-glucose-46-dehydratase; n=2;
           Halobacteriaceae|Rep: DTDP-glucose-46-dehydratase -
           Haloarcula marismortui (Halobacterium marismortui)
          Length = 294

 Score = 39.5 bits (88), Expect = 0.15
 Identities = 57/223 (25%), Positives = 92/223 (41%), Gaps = 25/223 (11%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVC---GDLGQVLFTPYHLLDEE 115
           V G TGF+GR +   L   G  ++   R    ++    V    GDLG+       L D+ 
Sbjct: 5   VMGATGFIGRRLVRALDDAGHDVVAFSRSASEESFPEGVEPFEGDLGEPDSLD-GLCDDI 63

Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 175
            +A  + +S     L   ++   + +Y        RR A      GV+R ++LS ++ +E
Sbjct: 64  DVAYYLIHS-----LTSENFAELDRRY-------ARRFADSASAAGVDRVVYLSGISGDE 111

Query: 176 HPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNL 235
                  +  S    S+   E  + E     T++RA+ I G E    R +V+ +     L
Sbjct: 112 -------ENLSPHLASRREVESVLAEGSFDLTVLRAAVIIGPESASFR-IVDDLTDRLPL 163

Query: 236 MPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGP 278
           M L    + T  QP+ V D    +V     D+T+ E Y   GP
Sbjct: 164 M-LVPKWVRTPCQPIGVDDAISYLVELLDADETRGETYDIGGP 205


>UniRef50_Q2W604 Cluster: Predicted nucleoside-diphosphate-sugar
           epimerase; n=1; Magnetospirillum magneticum AMB-1|Rep:
           Predicted nucleoside-diphosphate-sugar epimerase -
           Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
          Length = 343

 Score = 39.1 bits (87), Expect = 0.20
 Identities = 22/63 (34%), Positives = 28/63 (44%)

Query: 114 EESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA 173
           E  +A  +   +VV+N  G      +     VH  G  R+ R C   GV R IHLS L A
Sbjct: 43  EAVLAAHLTGHDVVVNAAGLVRGRGSNTMAAVHAQGTERLVRACLAAGVSRLIHLSALGA 102

Query: 174 EEH 176
             H
Sbjct: 103 SSH 105


>UniRef50_A1VMB7 Cluster: NAD-dependent epimerase/dehydratase; n=3;
           Comamonadaceae|Rep: NAD-dependent epimerase/dehydratase
           - Polaromonas naphthalenivorans (strain CJ2)
          Length = 305

 Score = 39.1 bits (87), Expect = 0.20
 Identities = 35/161 (21%), Positives = 62/161 (38%), Gaps = 6/161 (3%)

Query: 127 VINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPLVLKKPS 186
           V+N VG   +  +     +H D  + +   C  +GV R IHLS L     P      K +
Sbjct: 75  VVNAVGVLRDGPHTPMQAIHTDVPKALFNACARQGVRRVIHLSALGIASSPSRYATAKRA 134

Query: 187 AWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATV 246
           A     +L +   ++       ++ S ++G             R    L+P  +   +  
Sbjct: 135 A---EAHL-QALTQQGALQGVALQPSIVFGPGGAGCELFTALARWPVMLLP--RQAFSAR 188

Query: 247 KQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287
            QPV++ ++A+ +   A      C     VGP+   LA  +
Sbjct: 189 VQPVWIRELAEVVATLAGPAAELCGTLPCVGPEGTPLASFI 229


>UniRef50_Q73MR8 Cluster: Epimerase/dehydratase, putative; n=2;
           Bacteria|Rep: Epimerase/dehydratase, putative -
           Treponema denticola
          Length = 329

 Score = 38.7 bits (86), Expect = 0.27
 Identities = 45/162 (27%), Positives = 76/162 (46%), Gaps = 25/162 (15%)

Query: 113 DEESIAKAVRYS-NVVINLVGR---DYETKNFKYNDVHVDGVRRIARICREEGVERFIHL 168
           D +S+ K +  S + VINL      D E K+  Y++V+VDG   + ++C E G+++ I  
Sbjct: 49  DIDSLKKELSSSLDCVINLAAEHRDDVEPKSL-YDEVNVDGAENVCKVCSELGIKKIIFT 107

Query: 169 SY--------LNAEEHPKPLVLKKPSAWKISKYLGECAVR-----EEYPTATIIRASDIY 215
           S         LN  E  K   +   + +  +K+L E   R     +   + TIIR + ++
Sbjct: 108 SSVAVYGFAPLNTNETGK---INYFNDYGRTKWLAEGKYRAWIENDNENSLTIIRPTVVF 164

Query: 216 GSEDRFLRSLVNKMRS-HSNLMPLYKNGLATVKQPVFVSDVA 256
           G ++R   ++ N +R   S   P   NG    K   +V +VA
Sbjct: 165 GEQNR--GNVYNLLRQISSGFFPFVGNG-KNKKSMAYVENVA 203


>UniRef50_Q11Z70 Cluster: Nucleoside-diphosphate-sugar epimerase;
           n=1; Cytophaga hutchinsonii ATCC 33406|Rep:
           Nucleoside-diphosphate-sugar epimerase - Cytophaga
           hutchinsonii (strain ATCC 33406 / NCIMB 9469)
          Length = 322

 Score = 38.7 bits (86), Expect = 0.27
 Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 5/117 (4%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           V G  G VG ++CN+L   G ++    R +  D   LK     G +      + D  S+ 
Sbjct: 4   VTGANGLVGSFLCNELAGKGYRVKALVR-EKSDTSLLKAVA--GSIELVYGDITDAGSLV 60

Query: 119 KAVRYSNVVINLVG--RDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA 173
            A+     V++       +  KN +    +V G R +  +  E+GV++ IH+S + A
Sbjct: 61  DAMEDVMCVVHTAAVISFWNKKNKEMYQTNVVGTRNVVDVALEKGVKKMIHISSIAA 117


>UniRef50_A7FIK2 Cluster: NAD-dependent epimerase/dehydratase family
           protein; n=11; Enterobacteriaceae|Rep: NAD-dependent
           epimerase/dehydratase family protein - Yersinia
           pseudotuberculosis IP 31758
          Length = 338

 Score = 38.7 bits (86), Expect = 0.27
 Identities = 40/162 (24%), Positives = 72/162 (44%), Gaps = 16/162 (9%)

Query: 142 YNDVHVDGVRRIARICREEGVERFIHLS----YLNAEEH---PKPLVLKK-PSAWKISKY 193
           ++  +V    ++A+    EGV+RFIH+S    Y +   H   P+     +  S +  SKY
Sbjct: 86  FHQTNVVVTHKLAQAAGREGVKRFIHISSPAVYFDFRHHHDLPETYRASRFSSHYASSKY 145

Query: 194 LGECAVRE---EYPTAT--IIRASDIYGSEDR-FLRSLVNKMRSHSNLMPLYKNGLATVK 247
             E  + E    YP  T  I+R   ++G  DR  +  L+ ++    N++ L   G A + 
Sbjct: 146 AAEQVLHECIAHYPDTTYVILRPRGLFGPHDRVIVPRLLQQLSRDRNVLRLPGGGQAQL- 204

Query: 248 QPVFVSDVAQGIVNAARDDDTKC-EVYQAVGPKRYLLADLVD 288
              FV +V   ++ A  +D  +   +Y     +   L  ++D
Sbjct: 205 DLTFVLNVVHAMMLATDNDGLRSGAIYNITNQEPQRLVTMLD 246


>UniRef50_A4BUQ8 Cluster: DTDP-4-dehydrorhamnose reductase; n=3;
           Proteobacteria|Rep: DTDP-4-dehydrorhamnose reductase -
           Nitrococcus mobilis Nb-231
          Length = 291

 Score = 38.7 bits (86), Expect = 0.27
 Identities = 33/107 (30%), Positives = 52/107 (48%), Gaps = 8/107 (7%)

Query: 136 ETKNFKYNDVHVDGVRRIARICREEGVERFIHLS----YLNAEEHP-KPLVLKKP-SAWK 189
           ET+      V+V G   +AR  RE G  R +H+S    +  A+  P  P     P + + 
Sbjct: 66  ETERAAAYAVNVGGAEHMARAARELGC-RLVHISTDFVFDGAQGRPYTPESKPNPLNVYG 124

Query: 190 ISKYLGECAVREEYPTATIIRASDIYG-SEDRFLRSLVNKMRSHSNL 235
            SK  GE A +   P A I+R + +YG +   F+ S++  MR+ + L
Sbjct: 125 ASKLAGEQAAQAIKPDALILRTAWLYGETGSNFVHSMLRLMRTRAEL 171


>UniRef50_A3CRA1 Cluster: DTDP-4-dehydrorhamnose 3,5-epimerase,
           putative; n=4; Bacteria|Rep: DTDP-4-dehydrorhamnose
           3,5-epimerase, putative - Streptococcus sanguinis
           (strain SK36)
          Length = 343

 Score = 38.3 bits (85), Expect = 0.35
 Identities = 56/242 (23%), Positives = 105/242 (43%), Gaps = 20/242 (8%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           V G TGF+G+YV  +L + G Q +  +  +    ++L+  G L  V F       EE I 
Sbjct: 23  VTGATGFLGKYVVEELAEQGYQ-VRAFGRNLKAGRQLE--GPL--VEFFAGDFTREEEIF 77

Query: 119 KAVRYSNVVINLVGRDYETKNF-KYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 177
            A    + V++          + ++   +V G + +   CR  GV+R +++S  +     
Sbjct: 78  AACEGVDAVVHAGALSTIWGPWEQFYQTNVVGTKLVMEACRHFGVQRLVYISSPSVYAAA 137

Query: 178 K-PLVLKKPSA--------WKISKYLGECAVREEYP--TATIIRASDIYGSEDRFLRSLV 226
           +  L +K+ +A        +  SK + E  VR  YP   + I+R   ++G  D  +   +
Sbjct: 138 RDQLDIKEEAAPQENELNFYIKSKLMAERIVR-SYPQVPSVILRPRGLFGIGDTSIFPRI 196

Query: 227 NKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADL 286
            ++ S    +PL +NG   +     V +VA  +  A    + + +VY     +     D+
Sbjct: 197 LRL-SQKLAIPLIRNG-QQMMDMTCVENVALAVRLALEIPEAQGQVYNITNGESRSFKDM 254

Query: 287 VD 288
           +D
Sbjct: 255 LD 256


>UniRef50_Q9A4D7 Cluster: Putative uncharacterized protein; n=1;
           Caulobacter vibrioides|Rep: Putative uncharacterized
           protein - Caulobacter crescentus (Caulobacter
           vibrioides)
          Length = 430

 Score = 37.9 bits (84), Expect = 0.46
 Identities = 42/163 (25%), Positives = 66/163 (40%), Gaps = 13/163 (7%)

Query: 127 VINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPLVLKKPS 186
           V+N  G   ++     N VHV+GVRR+A+ C E    R +H+S    E         KP+
Sbjct: 69  VVNCAGALQDSPRDDLNAVHVEGVRRLAQAC-EAKRARLVHISAAGVE-------ADKPT 120

Query: 187 AWKISKYLGECAVREEYPTA--TIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLA 244
           A+  +K+  E A+    P     ++R   + G       +L+  +       P+  +G +
Sbjct: 121 AFNTTKHEAE-ALLAAMPALDWVVLRPGLVIGPAAYGGTALLRGLAGFPGFSPVV-HGQS 178

Query: 245 TVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287
            V Q V   DVA  +      D         V  +   L DLV
Sbjct: 179 RV-QVVATDDVAAAVARCLAPDAPLRRRLDLVHAEAVTLTDLV 220


>UniRef50_Q82X00 Cluster: Putative UDP-glucose 4-epimerase; n=1;
           Nitrosomonas europaea|Rep: Putative UDP-glucose
           4-epimerase - Nitrosomonas europaea
          Length = 315

 Score = 37.9 bits (84), Expect = 0.46
 Identities = 41/149 (27%), Positives = 69/149 (46%), Gaps = 12/149 (8%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           V G  GFVG+ +C  L + G + +   R      + + V    G+   T +  + +E I 
Sbjct: 5   VTGANGFVGQTLCPALERAGLRAVRAVRISTR-YEEISVGEVDGE---TSWSRVFDEGID 60

Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLN--AEEH 176
             V  +   + L  ++ E  +  Y+ V+  G  R+AR C   G+ RF+ +S +    EE 
Sbjct: 61  GVVHLA-AKVPLAEKEKEAAD-SYHRVNTLGTVRLARECAARGIRRFVFISTVKVLGEEC 118

Query: 177 PKPLVLKK---PS-AWKISKYLGECAVRE 201
            KP        PS A+ ISK+  E ++R+
Sbjct: 119 DKPFQADDSAVPSDAYAISKWEAEQSLRQ 147


>UniRef50_Q2Y734 Cluster: NAD-dependent epimerase/dehydratase
           precursor; n=1; Nitrosospira multiformis ATCC 25196|Rep:
           NAD-dependent epimerase/dehydratase precursor -
           Nitrosospira multiformis (strain ATCC 25196 / NCIMB
           11849)
          Length = 439

 Score = 37.9 bits (84), Expect = 0.46
 Identities = 54/242 (22%), Positives = 97/242 (40%), Gaps = 17/242 (7%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYR-GDFYDAQRLKVCGDLGQVLFTPYHL--LDEE 115
           + G +GF+G ++   L   G +++   R G   D + +K     G            D E
Sbjct: 6   ITGASGFIGSHLVMALAAAGHRIVCATRRGQPEDIRGIKDLKGTGPTYIAADFTRDFDME 65

Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 175
              K +   +VVIN VG   E     +  +H    R +   C    V + + +S L A+E
Sbjct: 66  VWKKRLAGIDVVINAVGILREHGRQTFQALHDRAPRALFAACEAANV-KVVQISALGADE 124

Query: 176 HPKPLVLKKPSAWKISKYLGECAVR---EEYPTATIIRASDIYGSEDRFLRSLVNKMRSH 232
           + +       S + +SK   + A+         + +++ S +YG      + L N + S 
Sbjct: 125 NAR-------SRYHLSKKAADDALLASPNNRSKSMVVQPSLVYGPGGTSAQ-LFNLIASL 176

Query: 233 SNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYK 292
             ++PL   G   + QP+ + D+ Q +V   + D    +    VGP+     D +     
Sbjct: 177 P-VIPLPGAGNQRI-QPIHIDDLTQAVVELLQTDRYLGQRIPLVGPEPITFRDYLGELRH 234

Query: 293 LM 294
           LM
Sbjct: 235 LM 236


>UniRef50_Q2S3D1 Cluster: NAD-dependent epimerase/dehydratase family
           protein/3-beta hydroxysteroid dehydrogenase/isomerase
           family protein; n=1; Salinibacter ruber DSM 13855|Rep:
           NAD-dependent epimerase/dehydratase family
           protein/3-beta hydroxysteroid dehydrogenase/isomerase
           family protein - Salinibacter ruber (strain DSM 13855)
          Length = 339

 Score = 37.9 bits (84), Expect = 0.46
 Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 2/67 (2%)

Query: 207 TIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDD 266
           T++R   +YG  DR +      ++ H  + P+   G A     V V D+A G+V+AAR  
Sbjct: 171 TVVRPPAVYGPRDRDILDFFRAVKRH--VCPIVGGGSARTLSLVHVRDLATGMVDAARHP 228

Query: 267 DTKCEVY 273
               E Y
Sbjct: 229 GAHGETY 235


>UniRef50_Q9X9X6 Cluster: Putative uncharacterized protein SCO1896;
           n=2; Streptomyces|Rep: Putative uncharacterized protein
           SCO1896 - Streptomyces coelicolor
          Length = 269

 Score = 37.5 bits (83), Expect = 0.61
 Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 1/106 (0%)

Query: 75  GKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRD 134
           G +GT +     G  Y+ + L +    G+       L D +++ +AVR  + +I+L G  
Sbjct: 14  GGLGTLMRELLPGHGYELRLLDLLPVEGEPDAIVADLADRDALREAVRGVDAIIHLAGIS 73

Query: 135 YETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEH-PKP 179
            E    K    +++G   +    REEGV R +  S  +A  + P+P
Sbjct: 74  LEASFDKILAANIEGTYNLYEAAREEGVGRIVFASSNHAVGYTPRP 119


>UniRef50_A7H9M3 Cluster: NAD-dependent epimerase/dehydratase
           precursor; n=4; Cystobacterineae|Rep: NAD-dependent
           epimerase/dehydratase precursor - Anaeromyxobacter sp.
           Fw109-5
          Length = 347

 Score = 37.5 bits (83), Expect = 0.61
 Identities = 33/110 (30%), Positives = 53/110 (48%), Gaps = 9/110 (8%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           V G TGF+G  +   L   G +L L  R     A+RL       +V+     L DE ++ 
Sbjct: 5   VTGATGFLGATLVPLLAAEGHRLRLLQRSAAPGAERLGA-----EVVRAS--LADEGAVR 57

Query: 119 KAVRYSNVVINLVGR-DYETKNFK-YNDVHVDGVRRIARICREEGVERFI 166
           +AVR  + V +L G+ D++    +   ++HV G RR+   C   G +R +
Sbjct: 58  EAVRGVDAVYHLAGQVDFDPAEPRALYELHVQGTRRLLEACVAAGTKRVV 107


>UniRef50_A6G7N0 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family protein; n=1;
           Plesiocystis pacifica SIR-1|Rep: Oxidoreductase, short
           chain dehydrogenase/reductase family protein -
           Plesiocystis pacifica SIR-1
          Length = 373

 Score = 37.5 bits (83), Expect = 0.61
 Identities = 36/131 (27%), Positives = 59/131 (45%), Gaps = 11/131 (8%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVL--FTPYHLLDE-E 115
           V G +GF+G ++C  L + G  +    R     A+      + G+V+     Y  LD+ +
Sbjct: 3   VTGASGFIGSHLCQVLRERGHAVQAMVRKTSKLAKLEDAAREGGRVIPFELAYASLDDVD 62

Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRI------ARICREEGVERFIHLS 169
           ++ +AVR   VV N+ G         ++  +V GV  +      AR    +G  R +H+S
Sbjct: 63  ALTEAVRGVEVVYNIAGTTAAFDRVGFDRTNVAGVDNLIAAIERARASEGKGPRRLVHVS 122

Query: 170 YLNA--EEHPK 178
            L A    HPK
Sbjct: 123 SLMAAGPSHPK 133


>UniRef50_A1ZKR0 Cluster: Putative dihydroflavonol-4-reductase; n=1;
           Microscilla marina ATCC 23134|Rep: Putative
           dihydroflavonol-4-reductase - Microscilla marina ATCC
           23134
          Length = 328

 Score = 37.5 bits (83), Expect = 0.61
 Identities = 34/140 (24%), Positives = 65/140 (46%), Gaps = 10/140 (7%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDL-GQVLFTPYHLLDEESI 117
           + GC+G VG ++  +L   G  +    R D      L    D+  Q+ +    +LD   +
Sbjct: 4   ITGCSGLVGSFIARRLLAAGHSVRALRRKD----SNLHYLTDIKDQIEWVEGDVLDVSRL 59

Query: 118 AKAVRYSNVVIN---LVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 174
              ++ +  VI+   LV    +TK+  Y  V+++G   +  I  E GV++ + +S + A 
Sbjct: 60  YDVMQGAKQVIHSAALVSFTPKTKDLMYK-VNIEGTANVVNISLELGVDKLVFISSVAAL 118

Query: 175 EHPKPL-VLKKPSAWKISKY 193
              K   V+ + + W+ SK+
Sbjct: 119 GRRKNTEVIDEKAQWEPSKF 138


>UniRef50_Q9UXL5 Cluster: DTDP-glucose 4,6-dehydratase; n=1;
           Sulfolobus solfataricus|Rep: DTDP-glucose
           4,6-dehydratase - Sulfolobus solfataricus
          Length = 317

 Score = 37.5 bits (83), Expect = 0.61
 Identities = 35/125 (28%), Positives = 59/125 (47%), Gaps = 9/125 (7%)

Query: 182 LKKPSAWKISKYLGECAVREEYPT----ATIIRASDIYGSEDRFLRSLVNKMRSHSNL-- 235
           LK  S +  SK   +  V+    T    A I+R S+ YG   +F   L+ K    + L  
Sbjct: 132 LKPSSPYSASKASADLFVKAYVRTYGISAVIVRPSNNYGPR-QFPEKLIPKAIIRTLLGI 190

Query: 236 -MPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLVDWFYKLM 294
            +P+Y +G A  +  +FV D A+ I +     + K EVY   G +RY + +++    ++ 
Sbjct: 191 HIPVYGDGKAE-RDWIFVEDTARIIFDVVSRAEWKGEVYNIPGGQRYNVLEILKMLEEVS 249

Query: 295 RKDEK 299
            K+ K
Sbjct: 250 GKEVK 254


>UniRef50_A0B7R7 Cluster: DTDP-4-dehydrorhamnose reductase; n=1;
           Methanosaeta thermophila PT|Rep: DTDP-4-dehydrorhamnose
           reductase - Methanosaeta thermophila (strain DSM 6194 /
           PT) (Methanothrixthermophila (strain DSM 6194 / PT))
          Length = 281

 Score = 37.5 bits (83), Expect = 0.61
 Identities = 36/122 (29%), Positives = 58/122 (47%), Gaps = 12/122 (9%)

Query: 145 VHVDGVRRIARICREEGVERFIHLS--YLNAEEHPKPLVLKKP----SAWKISKYLGECA 198
           V+  G R  A   R  G  +F+H+S  Y+   +   P V   P    + +  SK LGE  
Sbjct: 75  VNAIGARNAAIAARRAGA-KFVHISTDYVFDGKKDGPYVEYDPPNPLNVYGWSKLLGERM 133

Query: 199 VREEYPTATIIRASDIYGSEDR-FLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQ 257
           V E+ P + I+R + +YG   R F++++++  R+   L  +  +   T   P F  DVA 
Sbjct: 134 VLEQNPDSFILRVAWLYGPAGRNFVKTMLSLARARDELR-VVNDQRGT---PTFAGDVAN 189

Query: 258 GI 259
            I
Sbjct: 190 QI 191


>UniRef50_Q8KB45 Cluster: NAD-dependent epimerase/dehydratase family
           protein/3-beta hydroxysteroid dehydrogenase/isomerase
           family protein; n=11; Chlorobiaceae|Rep: NAD-dependent
           epimerase/dehydratase family protein/3-beta
           hydroxysteroid dehydrogenase/isomerase family protein -
           Chlorobium tepidum
          Length = 335

 Score = 37.1 bits (82), Expect = 0.81
 Identities = 56/244 (22%), Positives = 101/244 (41%), Gaps = 17/244 (6%)

Query: 56  VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 115
           V  V G TGF+G  + + L   G ++ +  R +            + +V    Y   D E
Sbjct: 6   VILVTGSTGFIGSRMVDALVGQGRRVRVLLRPESRSTLSAGYREGVEEVC-AAYG--DPE 62

Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREE--GVERFIHLSYLNA 173
           ++ +AV     +I+L G         + + +V  V  +    +    G+ RF+ +S L A
Sbjct: 63  ALGRAVSGVASIIHLAGVTKAVDEAGFAEGNVRPVENLLEAVKRHNPGLGRFLLVSSLAA 122

Query: 174 ---EEHPKPLVLK----KP-SAWKISKYLGECAVREEYPTA--TIIRASDIYGSEDRFLR 223
                 P P V++    +P SA+  SK LGE   R    +   TI+R   +YG  DR + 
Sbjct: 123 MGPASSPSPGVMESDRPRPVSAYGRSKLLGEAVARRHAGSVPLTIVRPPAVYGPGDRDIL 182

Query: 224 SLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLL 283
            +   M++   L      G       + V ++ +GI+ A   ++   + Y    P+ Y  
Sbjct: 183 EVFTMMKNGYLLSA--GPGRRQRFSMIHVDELIRGILLALDSENAAGQDYFITSPRGYAW 240

Query: 284 ADLV 287
            +++
Sbjct: 241 DEVI 244


>UniRef50_Q11DG7 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Mesorhizobium sp. BNC1|Rep: NAD-dependent
           epimerase/dehydratase - Mesorhizobium sp. (strain BNC1)
          Length = 305

 Score = 37.1 bits (82), Expect = 0.81
 Identities = 42/165 (25%), Positives = 73/165 (44%), Gaps = 17/165 (10%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           V G TGF+GR++   L K G +++   R  +  A R    GD+G    T +        +
Sbjct: 6   VTGATGFIGRHLVPVLLKRGHEVVEVGRRTYESAGRFVAVGDIGPT--TDW--------S 55

Query: 119 KAVRYSNVVINLVGRDY--ETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEH 176
            A+   + VI+L G  +  +     +  V+  G RR+A   +  G +  + LS + A E 
Sbjct: 56  PALGGVDAVIHLAGLAHREDADEAMFFSVNDAGTRRLAEAAQAAGAKVLVALSSIAAREA 115

Query: 177 PKPLVLKKPSAWKISKYLGECAVR---EEYPTATIIRASDIYGSE 218
            +    +K +A+  SK   E   R   E    + ++R   +YG +
Sbjct: 116 EQN--PQKANAYGRSKLASEAHARSFAEGGGVSIVLRPPLVYGHD 158


>UniRef50_A4VPL6 Cluster: DTDP-4-dehydrorhamnose reductase; n=8;
           Proteobacteria|Rep: DTDP-4-dehydrorhamnose reductase -
           Pseudomonas stutzeri (strain A1501)
          Length = 306

 Score = 37.1 bits (82), Expect = 0.81
 Identities = 45/183 (24%), Positives = 74/183 (40%), Gaps = 21/183 (11%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           V G  G VGR +  +  + G  ++ P R     A+  +V   + Q           E I 
Sbjct: 5   VCGAGGQVGRELVERASRFGLDVLAPARAQLDIAKPEQVADAMRQ---------RPELII 55

Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERF-IHLSYLNAEEHP 177
            A  Y++V       + E+   +   V+ DG R +A   +  GV  F I   Y+ + E  
Sbjct: 56  NAAAYTHV------DNAESHGEQAYAVNRDGPRHLAEAAKHAGVPLFHISTDYVFSGEAT 109

Query: 178 KPLVLKKPSA----WKISKYLGECAVREEYPTATIIRASDIYGSE-DRFLRSLVNKMRSH 232
           +P      +     +  SK  GE A+R   P   I+R S +YG     F+++++   R  
Sbjct: 110 RPYTESDETGPTGVYGASKLAGEEAIRSCLPAHLILRTSWVYGVHGHNFVKTMLRLARQR 169

Query: 233 SNL 235
             L
Sbjct: 170 DAL 172


>UniRef50_A1B7X9 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Paracoccus denitrificans PD1222|Rep: NAD-dependent
           epimerase/dehydratase - Paracoccus denitrificans (strain
           Pd 1222)
          Length = 302

 Score = 37.1 bits (82), Expect = 0.81
 Identities = 54/227 (23%), Positives = 96/227 (42%), Gaps = 35/227 (15%)

Query: 54  GIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLD 113
           G    V G +GF+GR++C  L   G + +   RG   +A+R        Q  ++P     
Sbjct: 5   GSFVGVTGASGFIGRHLCADLRAAGLRPVAIGRGP--EAER--------QTDYSP----- 49

Query: 114 EESIAKAVRYSNVVINLVGR-----DYETKNFKYNDVHVDGVRRIARICREEGVERFIHL 168
            ES+  A+     V++L GR     D   +   +   +V+    +AR  + EGVER +  
Sbjct: 50  -ESLRAALAGCAAVVHLAGRRMTREDAPMELAPFLGPNVEATGHLARAAQAEGVERIVFA 108

Query: 169 SYLNAEEHPKPLVLKKP------SAWKISK-----YLGECAVREEYPTATIIRASDIYGS 217
           S +       P   ++       +A+ +SK     YL   A   + P A  +R + +YG 
Sbjct: 109 STIAVYSAASPAPWREDGPVHPVNAYALSKLMAEHYLEMLARARQAPPALSLRFAAVYGH 168

Query: 218 EDRFLRSLVN--KMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNA 262
            ++   +L+      +    + L  N   T+ Q ++V+D    I+ A
Sbjct: 169 GEKGTPALMKFVNQAAAGETITLSGNPDYTIDQ-LYVTDATAAILAA 214


>UniRef50_A3LUX6 Cluster: Protein FMP52-1, mitochondrial precursor;
           n=2; Saccharomycetaceae|Rep: Protein FMP52-1,
           mitochondrial precursor - Pichia stipitis (Yeast)
          Length = 226

 Score = 37.1 bits (82), Expect = 0.81
 Identities = 35/131 (26%), Positives = 60/131 (45%), Gaps = 10/131 (7%)

Query: 139 NFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECA 198
           NFK  D  ++     A+  +  GVE F+ +S + A      L L+      +   L E  
Sbjct: 85  NFKKIDYGIN--YEAAKAAKAAGVETFVLVSTIGANAQSSFLYLQ------VKGQLEEDI 136

Query: 199 VREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQG 258
           +  ++P   I+R   + G  +   + L+N + S   L  L+   L  +  P+F ++VAQ 
Sbjct: 137 IALKFPRTIILRPGILLGERETS-KGLLNNL-SVGVLKYLHGTPLTFLGNPIFGAEVAQI 194

Query: 259 IVNAARDDDTK 269
            VNAA++   K
Sbjct: 195 AVNAAQESFEK 205


>UniRef50_Q1H1D1 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Methylobacillus flagellatus KT|Rep: NAD-dependent
           epimerase/dehydratase - Methylobacillus flagellatus
           (strain KT / ATCC 51484 / DSM 6875)
          Length = 450

 Score = 36.7 bits (81), Expect = 1.1
 Identities = 43/171 (25%), Positives = 73/171 (42%), Gaps = 12/171 (7%)

Query: 125 NVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPLVLKK 184
           +VVIN VG   E     ++ +H      + R C++  V   I +S L A+E         
Sbjct: 86  DVVINAVGLLREHDGQTFDTLHEQAPAALFRACQQSQVGLVIQISALGADE-------AA 138

Query: 185 PSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLA 244
            SA+ +SK   +  +R     A I++ S ++G +    R     M +   ++PL   G  
Sbjct: 139 ASAYHLSKKAADDVLRTLDIPAFILQPSLVFGPDGSSARLFT--MLASMPVLPL-PGGGC 195

Query: 245 TVKQPVFVSDVAQGIVNAARDDDTKCEVYQAV-GPKRYLLADLVDWFYKLM 294
            + QPV + D+   +V A    +    +  AV GP+   L +  D   + M
Sbjct: 196 QLLQPVHIHDLT-ALVQALTPLNPAGTITIAVAGPQALTLREYTDLLRRQM 245


>UniRef50_Q1ARG5 Cluster: DTDP-4-dehydrorhamnose reductase; n=1;
           Rubrobacter xylanophilus DSM 9941|Rep:
           DTDP-4-dehydrorhamnose reductase - Rubrobacter
           xylanophilus (strain DSM 9941 / NBRC 16129)
          Length = 278

 Score = 36.7 bits (81), Expect = 1.1
 Identities = 33/122 (27%), Positives = 55/122 (45%), Gaps = 11/122 (9%)

Query: 145 VHVDGVRRIARICREEGVERFIHLS----YLNAEEHP-KPLVLKKP-SAWKISKYLGECA 198
           V+  G R +A++C   G E  +H+S    +    E P +P     P S +  +K  GE  
Sbjct: 79  VNALGPRNLAQLCERLGCE-LLHVSTNYVFDGRSERPYEPWDRPNPISVYGATKLAGEEY 137

Query: 199 VREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQG 258
           VR       I+R + +YG    F+R+++   R  S L       ++    P +  D+A G
Sbjct: 138 VRHLTGRWYIVRTAGVYGEGRNFVRTMLRAARERSTLKVKDDEYIS----PTYARDLAGG 193

Query: 259 IV 260
           I+
Sbjct: 194 II 195


>UniRef50_Q11CJ7 Cluster: NAD-dependent epimerase/dehydratase; n=5;
           Rhizobiales|Rep: NAD-dependent epimerase/dehydratase -
           Mesorhizobium sp. (strain BNC1)
          Length = 429

 Score = 36.7 bits (81), Expect = 1.1
 Identities = 52/229 (22%), Positives = 82/229 (35%), Gaps = 14/229 (6%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           V G TG +G  VC +L   G  +I   R            G    V          +  A
Sbjct: 5   VTGATGLIGSTVCARLMSEGHHVIAVVR----PGSNPLPSGAAQIVEIDMARATGVQIWA 60

Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 178
           + +     V+N VG   ++       VHV G   + R C    + R IH S +  +    
Sbjct: 61  EHLFGVEAVVNCVGALQDSAREDTEGVHVTGAAALFRACERLSIRRVIHFSAIGVDR--- 117

Query: 179 PLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPL 238
                +PSA+  +K  G+  + E      I+R S + G       +L+   R  S L   
Sbjct: 118 ----AQPSAFSATKLEGDHLLMERDLDWVILRPSVVLGRNVFGASALI---RGLSALPFA 170

Query: 239 YKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLADLV 287
              G     Q V + DVA  +    +         +  GP+R  + ++V
Sbjct: 171 LSLGRTAPLQVVQLDDVAATVAFFIQPTAPVQVTLELAGPERLPMDEVV 219


>UniRef50_Q0M547 Cluster: NAD-dependent epimerase/dehydratase:3-beta
           hydroxysteroid
           dehydrogenase/isomerase:dTDP-4-dehydrorhamnose
           reductase:NmrA- like:Male sterility-like; n=2;
           Caulobacter|Rep: NAD-dependent
           epimerase/dehydratase:3-beta hydroxysteroid
           dehydrogenase/isomerase:dTDP-4-dehydrorhamnose
           reductase:NmrA- like:Male sterility-like - Caulobacter
           sp. K31
          Length = 322

 Score = 36.7 bits (81), Expect = 1.1
 Identities = 50/186 (26%), Positives = 79/186 (42%), Gaps = 15/186 (8%)

Query: 54  GIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLD 113
           G V  V G TGF+GR +   L + G  + +  R D  D     +     ++      L +
Sbjct: 8   GPVVAVTGATGFLGRRLVRILAEEGWTVRVLARRDIADPAWRGL-----ELQLAIGDLAN 62

Query: 114 EESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA 173
             ++A     +  VI++ G         ++  +V+G R++A   +  G  R + +S L A
Sbjct: 63  PRALAALCDGAETVIHVAGLIKARSRAVFDKANVEGSRQVALAAKAAGA-RLVLVSSLAA 121

Query: 174 EEHPKPLVLKKPSAWKISKYLGECAVREEY-PTATIIRASDIYGSEDRFLRSLVNKMRSH 232
            E   P +    S +  SK  GE A RE +    TI+R   IYG  D     L  KM S 
Sbjct: 122 RE---PHL----SDYAGSKRGGEDAAREIFGADLTIVRPPAIYGPGDIETLRLF-KMASE 173

Query: 233 SNLMPL 238
              +P+
Sbjct: 174 GAFLPV 179


>UniRef50_A3ACC5 Cluster: Putative uncharacterized protein; n=2;
           Oryza sativa|Rep: Putative uncharacterized protein -
           Oryza sativa subsp. japonica (Rice)
          Length = 272

 Score = 36.7 bits (81), Expect = 1.1
 Identities = 19/41 (46%), Positives = 26/41 (63%), Gaps = 1/41 (2%)

Query: 248 QPVFVSDVAQGIVNAARDDDTKC-EVYQAVGPKRYLLADLV 287
           QPV+V DVA  IVN+ +DD T   + Y   GP+ Y + DL+
Sbjct: 144 QPVYVVDVAAAIVNSLKDDGTSMGKSYGLGGPEIYTVHDLL 184


>UniRef50_Q9HCX3 Cluster: Zinc finger protein 304; n=4; Homo
           sapiens|Rep: Zinc finger protein 304 - Homo sapiens
           (Human)
          Length = 659

 Score = 36.7 bits (81), Expect = 1.1
 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 5/91 (5%)

Query: 85  YRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYND 144
           ++GD YD Q L  CGD G+     + LLD +     VR    +    G  ++ K+   N 
Sbjct: 213 HQGD-YDGQMLFSCGDEGKAFLDTFTLLDSQMTHAEVRPFRCL--PCGNVFKEKSALINH 269

Query: 145 VHVDGVRRIARICREEGVERFIHLSYLNAEE 175
             +     I+ +C+E G + FIHL +L   +
Sbjct: 270 RKIHS-GEISHVCKECG-KAFIHLHHLKMHQ 298


>UniRef50_Q8KB60 Cluster: Dihydroflavonol 4-reductase family; n=8;
           Chlorobiaceae|Rep: Dihydroflavonol 4-reductase family -
           Chlorobium tepidum
          Length = 333

 Score = 36.3 bits (80), Expect = 1.4
 Identities = 32/124 (25%), Positives = 56/124 (45%), Gaps = 6/124 (4%)

Query: 53  NGIVATVFGCTGFVG-RYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHL 111
           +GI   + G TG++G R + + + + G  +    R    +        +L  V      +
Sbjct: 2   SGIPILITGATGYIGARLLVDMIARYGDSVRC--RVTVREGSDASFLRNL-PVEIAQADM 58

Query: 112 LDEESIAKAVRYSNVVINLVGRDYETKNFKYN--DVHVDGVRRIARICREEGVERFIHLS 169
            D  ++ +AV+ + VV +  G    T+NF+    D +V G R I   C E GV+R +  S
Sbjct: 59  HDPIAVNEAVKGAEVVFHCAGLIAYTRNFRNRLYDTNVLGTRHIVDACLEAGVKRLVATS 118

Query: 170 YLNA 173
            + A
Sbjct: 119 SIAA 122


>UniRef50_Q2FQM3 Cluster: Putative uncharacterized protein
           precursor; n=1; Methanospirillum hungatei JF-1|Rep:
           Putative uncharacterized protein precursor -
           Methanospirillum hungatei (strain JF-1 / DSM 864)
          Length = 345

 Score = 36.3 bits (80), Expect = 1.4
 Identities = 18/43 (41%), Positives = 22/43 (51%)

Query: 135 YETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 177
           Y   N K  D+  D  R I RI REEG    I + ++NAE  P
Sbjct: 161 YWNGNQKGQDLFKDAYRHIIRIMREEGASNLIWIYHVNAESQP 203


>UniRef50_Q8DE28 Cluster: Nucleoside-diphosphate-sugar epimerase;
           n=6; Proteobacteria|Rep: Nucleoside-diphosphate-sugar
           epimerase - Vibrio vulnificus
          Length = 303

 Score = 35.9 bits (79), Expect = 1.9
 Identities = 40/153 (26%), Positives = 69/153 (45%), Gaps = 17/153 (11%)

Query: 125 NVVINLVG--RDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYL---NAEEHPKP 179
           N +I+L G    +   +  YN V+V G  R+A    E GV RF+ +S +         +P
Sbjct: 58  NTIIHLAGLAHSHSFSSKDYNRVNVAGTLRLATKAAEAGVRRFVFVSSIGVNGTSTQAEP 117

Query: 180 LVL-KKPSA---WKISKYLGECAV----REEYPTATIIRASDIYGSEDRFLRSLVNKMRS 231
             L  +PS    +  SKY  E  +    +E      I+R + +YG +      ++ K+  
Sbjct: 118 FALDSEPSPHNDYAQSKYDAEIGLKKIAKETGLEVVIVRPTLVYGPDAPGNFGMLTKLIK 177

Query: 232 HSNLMPLYKNGLATVKQP-VFVSDVAQGIVNAA 263
              ++P    GLAT ++  + V ++A  +V  A
Sbjct: 178 RLPVLPF---GLATNRRDFISVQNLADLLVTCA 207


>UniRef50_Q3VWW5 Cluster: Dihydroflavonol 4-reductase family; n=2;
           Chlorobiaceae|Rep: Dihydroflavonol 4-reductase family -
           Prosthecochloris aestuarii DSM 271
          Length = 341

 Score = 35.9 bits (79), Expect = 1.9
 Identities = 36/127 (28%), Positives = 54/127 (42%), Gaps = 12/127 (9%)

Query: 53  NGIVATVFGCTGFVGRYVCNKLGKI---GTQL-ILPYRGDFYDAQRLKVCGDLGQVLFTP 108
           +G V  V G TG++G  +  +L  +   G  L +L  RG   D   L    D   V F  
Sbjct: 10  SGRVILVTGATGYIGSELVERLSSLCDAGLHLRVLARRGS--DVSVL----DGNSVEFVY 63

Query: 109 YHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYN--DVHVDGVRRIARICREEGVERFI 166
             LLD  S+  A    + V +  G    ++N++      +V G   +   C  EGV R +
Sbjct: 64  GDLLDSLSLYDACSGVDTVFHCAGLIAYSRNYRQRLYATNVTGTGNLVNACLAEGVTRLV 123

Query: 167 HLSYLNA 173
           H S + A
Sbjct: 124 HTSSVAA 130


>UniRef50_A1ULW0 Cluster: NAD-dependent epimerase/dehydratase; n=4;
           Mycobacterium|Rep: NAD-dependent epimerase/dehydratase -
           Mycobacterium sp. (strain KMS)
          Length = 325

 Score = 35.9 bits (79), Expect = 1.9
 Identities = 50/211 (23%), Positives = 85/211 (40%), Gaps = 15/211 (7%)

Query: 53  NGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLL 112
           + I   V G TG++G  +   L   G Q+    R       +L       QV      L+
Sbjct: 3   DNIRCLVTGATGYIGGRLVPALLDRGLQV----RAMARTPGKLDDAPWRAQVEVAKGDLM 58

Query: 113 DEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLN 172
           D ES+A A    +VV  LV     +KNF   +   +    +    ++ GV R ++LS L 
Sbjct: 59  DRESLAAAFEGMDVVYYLVHSMGTSKNFVAEE--AESAHNVVAAAKQAGVRRVVYLSGL- 115

Query: 173 AEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSH 232
              HP+ + L +  A +    +GE  +     T  +++A  + GS       ++  +   
Sbjct: 116 ---HPEGVELSRHLASRTE--VGEILIDSGIET-MVLQAGIVVGSGSASF-EMIRHLTDR 168

Query: 233 SNLMPLYKNGLATVKQPVFVSDVAQGIVNAA 263
             +M   K  +    QP+ + D    +V AA
Sbjct: 169 LPIMTAPK-WVHNKIQPISIDDALYYLVEAA 198


>UniRef50_A0QDT4 Cluster: Putative uncharacterized protein; n=1;
           Mycobacterium avium 104|Rep: Putative uncharacterized
           protein - Mycobacterium avium (strain 104)
          Length = 214

 Score = 35.9 bits (79), Expect = 1.9
 Identities = 34/112 (30%), Positives = 52/112 (46%), Gaps = 8/112 (7%)

Query: 58  TVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 117
           TVFG TG +GR+V   L   G       R    +  +L+V      +      L D E++
Sbjct: 6   TVFGATGQIGRFVVADLLADGHAATAYVR----NPGKLQVADP--HLTVATGELSDAEAV 59

Query: 118 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLS 169
            KAVR ++ VI+ +G    ++  K   V  +G R I    + E V R+I L+
Sbjct: 60  RKAVRGADAVISALGPSL-SRRAKGTPV-TEGTRNIVAAMQAEHVSRYIGLA 109


>UniRef50_Q0S304 Cluster: DTDP-4-dehydrorhamnose reductase; n=1;
           Rhodococcus sp. RHA1|Rep: DTDP-4-dehydrorhamnose
           reductase - Rhodococcus sp. (strain RHA1)
          Length = 262

 Score = 35.5 bits (78), Expect = 2.5
 Identities = 34/135 (25%), Positives = 56/135 (41%), Gaps = 11/135 (8%)

Query: 159 EEGVERFIHLS--YLNAEEHPKPLVLKKPS----AWKISKYLGECAVREEYPTATIIRAS 212
           +E   R IH+S  Y+ A +   P  +  P+    A+  +K  GE AV    P+A ++R +
Sbjct: 69  DEDTARLIHVSTDYVFAGQGDTPYEVDAPTGPATAYGRTKLAGERAVHAALPSAHVVRTA 128

Query: 213 DIY-GSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCE 271
            +Y G    F+ +++   R    +  +       V  P F  D+A  ++  A   D    
Sbjct: 129 WVYTGVGSDFVSTMLRLERERDTVDVVDDQ----VGSPTFAGDLADALLELAGRSDVDAP 184

Query: 272 VYQAVGPKRYLLADL 286
           V  A    R    DL
Sbjct: 185 VLHATNSGRASWFDL 199


>UniRef50_Q0BVL3 Cluster: NADH-ubiquinone oxidoreductase 39-40 kDa
           subunit-like protein; n=1; Granulibacter bethesdensis
           CGDNIH1|Rep: NADH-ubiquinone oxidoreductase 39-40 kDa
           subunit-like protein - Granulobacter bethesdensis
           (strain ATCC BAA-1260 / CGDNIH1)
          Length = 323

 Score = 35.5 bits (78), Expect = 2.5
 Identities = 53/210 (25%), Positives = 91/210 (43%), Gaps = 17/210 (8%)

Query: 56  VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 115
           +A V G TGF+G +    L + G  +    R      +   +  D G +   P  L DE 
Sbjct: 7   IAAVTGATGFLGCHTVAALAERGFHV----RALIRRPEPHPLWQDRG-IETVPGDLADET 61

Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARIC-REEGVERFIHLSYLNAE 174
           ++ + +  ++VV++L G         +  V+ DG  R+A +  R     R I +S L A 
Sbjct: 62  ALQRLLTGADVVLHLAGLVRARSPKAFLAVNRDGAFRLASMLQRCAPAARLIGISSLAAR 121

Query: 175 EHPKPLVLKKPSAWKISKYLGECAVREEY-PTATIIRASDIYGSEDRFLRSLVNKMRSHS 233
               P +    SA+  SK  GE A+R+ +     I+R   IYG  D    S+     + +
Sbjct: 122 ---APHL----SAYAASKSAGEQALRDGFGGKLCIVRPPVIYGPWDTATLSIFRS--AAA 172

Query: 234 NLMPLYKNGLATVKQPVFVSDVAQGIVNAA 263
            ++P+  +  + +   + V+D A  I   A
Sbjct: 173 RIVPVAGHSRSRIAM-IHVADAADAIAALA 201


>UniRef50_Q0AIT5 Cluster: NAD-dependent epimerase/dehydratase; n=3;
           Nitrosomonadaceae|Rep: NAD-dependent
           epimerase/dehydratase - Nitrosomonas eutropha (strain
           C71)
          Length = 307

 Score = 35.5 bits (78), Expect = 2.5
 Identities = 51/178 (28%), Positives = 82/178 (46%), Gaps = 23/178 (12%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYR--GDFYDAQRLK-VCGDLGQVLFTPYHLLDEE 115
           V G TGF+GR +  KL + G ++    R      D+  ++ + GDLG        L D  
Sbjct: 7   VTGATGFIGRILIAKLAESGWKIRALARCISSQKDSPFIEWISGDLG----CNNALRDLV 62

Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREE-GVERFIHLSYLNAE 174
           S A+AV +   V+   G+ ++     +   +V G R I R+  +     RF+H+S L A 
Sbjct: 63  SGAEAVIHCAGVVK--GKSWD----DFYQTNVIGTRNILRVASDSTSCSRFLHISSLAAR 116

Query: 175 EHPKPLVLKKPSAWKISKYLGECAV-REEYPTATII-RASDIYGSEDRFLRSLVNKMR 230
           E   PL+    S +  SK+  E  + R     A++I R + +YG  D+ +      MR
Sbjct: 117 E---PLL----SWYARSKFEAEEQIPRFSGRLASVIYRPAAVYGPGDKAMLPFFRSMR 167


>UniRef50_A6LP17 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Thermosipho melanesiensis BI429|Rep: NAD-dependent
           epimerase/dehydratase - Thermosipho melanesiensis BI429
          Length = 335

 Score = 35.5 bits (78), Expect = 2.5
 Identities = 22/68 (32%), Positives = 38/68 (55%), Gaps = 3/68 (4%)

Query: 113 DEESIAKAVRYSNVVINLVG--RDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSY 170
           D E++ K  R ++++I+L         K  K   V+V+G R I  IC + G +R I++S 
Sbjct: 53  DYETVKKFARNADLIIHLAAYISILPWKKKKVFSVNVNGTRNIINICMKTG-KRLIYVSS 111

Query: 171 LNAEEHPK 178
           ++A E P+
Sbjct: 112 VHAFEEPR 119


>UniRef50_A5I358 Cluster: Molybdopterin biosynthesis protein; n=4;
           Clostridium botulinum|Rep: Molybdopterin biosynthesis
           protein - Clostridium botulinum A str. ATCC 3502
          Length = 227

 Score = 35.5 bits (78), Expect = 2.5
 Identities = 30/117 (25%), Positives = 45/117 (38%), Gaps = 9/117 (7%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLK---VCGDLGQVLFTPYHLLDEE 115
           V GC G +G Y+   LG+IG   I    GD +    L    +  DL              
Sbjct: 26  VIGCGG-LGGYIIEMLGRIGVGHITAVDGDTFSESNLNRQIISSDLNLGKNKAIEAKKRM 84

Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRI-ARICREEGVER----FIH 167
            +   + Y N +   + +D      K +DV +D +  I  R   +E  E+    FIH
Sbjct: 85  KVVNDLIYVNPITTFINKDNVLNILKEHDVVIDAIDNIETRFLLQESCEKLKIPFIH 141


>UniRef50_A0Z741 Cluster: Nucleoside-diphosphate-sugar epimerase;
           n=1; marine gamma proteobacterium HTCC2080|Rep:
           Nucleoside-diphosphate-sugar epimerase - marine gamma
           proteobacterium HTCC2080
          Length = 299

 Score = 35.5 bits (78), Expect = 2.5
 Identities = 35/125 (28%), Positives = 59/125 (47%), Gaps = 15/125 (12%)

Query: 126 VVINLVGRDYETKNFK-YNDVHVDGVRRIARICREEGVERFIHLSYLNAEE----HPKPL 180
           VVI+  G  +   +F  Y  V+V+  R +A      GV++FI +S LN        P  L
Sbjct: 55  VVIHCAGIAHSKGDFSAYQQVNVEACRALASAAEVAGVKQFIFMSSLNVVPATIIDPGTL 114

Query: 181 VLKKP---SAWKISKYLGECAVREEYPTAT----IIRASDIYGSEDRFLRSLVNKMRSHS 233
             + P   S +  SK+  E AV  E  +++    I+R + +Y   DR L + +  ++   
Sbjct: 115 ASEIPEPLSPYAASKWQAEIAVSRELSSSSCELVILRPALVY---DRTLTANLAALKKWQ 171

Query: 234 NLMPL 238
            L+P+
Sbjct: 172 RLLPV 176


>UniRef50_A3H8S6 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Caldivirga maquilingensis IC-167|Rep: NAD-dependent
           epimerase/dehydratase - Caldivirga maquilingensis IC-167
          Length = 315

 Score = 35.5 bits (78), Expect = 2.5
 Identities = 49/169 (28%), Positives = 74/169 (43%), Gaps = 20/169 (11%)

Query: 64  GFVGRYVCNKLGKIGTQLILPYRG-DFYDAQRLKVCGDLGQVLFTPYH-LLDEESIAKAV 121
           GF+  +V   L KIG Q+ + YR  +  +    KV    G V  T  + L DE+ +   +
Sbjct: 10  GFIATHVAEGLSKIG-QVTVTYRSLNGVNEVYAKVLR--GSVELTRLNPLTDEDELRGLI 66

Query: 122 RYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVE-RFIHLSYLNA------- 173
           + S+ VINL+G            VHV   R++A +  E       +H+S  N        
Sbjct: 67  KNSDTVINLIGALGNDAQL-LRTVHVVIPRQVASLIAEYSPSTMLVHVSASNVMGPIGKF 125

Query: 174 -EEHPKPLVLKKPSA-WKISKYLGECAVREEYPTA----TIIRASDIYG 216
             E PK     +PS  ++ +K LGE  V     +A     IIR + +YG
Sbjct: 126 INEEPKHCEGARPSTPYEETKCLGEQVVYSMSQSAGFPLAIIRPTLVYG 174


>UniRef50_Q2S430 Cluster: Nucleoside-diphosphate-sugar epimerase;
           n=1; Salinibacter ruber DSM 13855|Rep:
           Nucleoside-diphosphate-sugar epimerase - Salinibacter
           ruber (strain DSM 13855)
          Length = 488

 Score = 35.1 bits (77), Expect = 3.3
 Identities = 34/127 (26%), Positives = 60/127 (47%), Gaps = 10/127 (7%)

Query: 154 ARICREEGVERFIHLSYLNAEEH-PKPLVLKKPSAWKISKYLGECAVREEYPTATIIRAS 212
           AR    EGV++ ++L  L  E+  P P  L++    ++ + LG  +V       T +RA 
Sbjct: 103 ARAAEAEGVDQILYLGALIPEDKSPLPSPLRR--RLEMEEVLGSTSV-----PLTTLRAG 155

Query: 213 DIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEV 272
            I G+   +L  L+N +R    +M L  +      QP+ + DV +G+  +  + +T    
Sbjct: 156 LIVGAGGTWLSMLLNLVR-RLPVMVL-PSWTRAETQPIALRDVVRGLEKSLGNPETYEAT 213

Query: 273 YQAVGPK 279
           Y   GP+
Sbjct: 214 YDVGGPE 220


>UniRef50_A0LKC0 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Syntrophobacter fumaroxidans MPOB|Rep: NAD-dependent
           epimerase/dehydratase - Syntrophobacter fumaroxidans
           (strain DSM 10017 / MPOB)
          Length = 312

 Score = 35.1 bits (77), Expect = 3.3
 Identities = 65/225 (28%), Positives = 95/225 (42%), Gaps = 22/225 (9%)

Query: 55  IVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDE 114
           IV  + G  GF+G  +  +L     ++ +    D   A R +   D   V F    + D 
Sbjct: 5   IVYLITGGAGFIGTNLIRRLSIPSVRIRVL---DNLSAGRREDL-DGFDVEFVQGDIQDA 60

Query: 115 ESIAKAVRYSNVVINLVGRD---YETKNFKYN-DVHVDGVRRIARICREEGVERFIHLSY 170
            ++ +AV  +  VI+L           N + N DV+V G   + R   E GVERF+  S 
Sbjct: 61  GAVHRAVAGARKVIHLAANTNVVQSVANPELNLDVNVRGTFNLLRASVEHGVERFVFAST 120

Query: 171 LNA--EEHPKPLVLKKP----SAWKISKYLGE--C-AVREEYPTATI-IRASDIYGSEDR 220
             A   +   P+    P    S +  SK  GE  C A    Y   T+ +R S+IYG    
Sbjct: 121 GGAIVGDVTPPVHEDMPPNPISPYGASKLAGEGYCSAFWGAYGLPTVSLRFSNIYGPFSY 180

Query: 221 FLRSLVNK-MRSHSNLMPL--YKNGLATVKQPVFVSDVAQGIVNA 262
              S++ K  R      PL  Y +G  T +  +FV D+ QGI  A
Sbjct: 181 HKGSVIAKFFREVQAGKPLTIYGDGEQT-RDFLFVGDLCQGIARA 224


>UniRef50_Q8DJM2 Cluster: Nucleotide sugar epimerase; n=61; cellular
           organisms|Rep: Nucleotide sugar epimerase -
           Synechococcus elongatus (Thermosynechococcus elongatus)
          Length = 338

 Score = 34.7 bits (76), Expect = 4.3
 Identities = 35/125 (28%), Positives = 53/125 (42%), Gaps = 14/125 (11%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLI-LPYRGDFYDA-------QRLKVCGDLGQVLFTPYH 110
           V G  GF+G      L + G ++I L    D+YD        + L +    GQ +F    
Sbjct: 5   VTGVAGFIGHGAALALLRRGDRVIGLDNLNDYYDVNLKKSRLEHLNISSQPGQFIFRKID 64

Query: 111 LLDEESIAKAVR-YS-NVVINLV---GRDYETKN-FKYNDVHVDGVRRIARICREEGVER 164
           L+D   + +    +S   VI+L    G  Y  +N F Y D ++ G   I   CR   VE 
Sbjct: 65  LVDRLGVNQLFADFSPQKVIHLAAQAGVRYSLENPFAYIDSNIVGFLHILEACRHHRVEH 124

Query: 165 FIHLS 169
            ++ S
Sbjct: 125 LVYAS 129


>UniRef50_Q6LH31 Cluster: Putative uncharacterized protein CT0995;
           n=4; Vibrionales|Rep: Putative uncharacterized protein
           CT0995 - Photobacterium profundum (Photobacterium sp.
           (strain SS9))
          Length = 287

 Score = 34.7 bits (76), Expect = 4.3
 Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 4/80 (5%)

Query: 125 NVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPLVLKK 184
           +VVI+ +G   +     Y DV       + +     GV +FI +S  NAE++P   +LK 
Sbjct: 70  DVVISCLGITRQRDGLGYMDVDYQANLNLLQEAERAGVSKFIDVSAFNAEKYPSVRLLKA 129

Query: 185 PSAWKI----SKYLGECAVR 200
              + +    S+ L  C +R
Sbjct: 130 KERFALRLLGSENLTPCVIR 149


>UniRef50_Q5WC54 Cluster: Putative uncharacterized protein; n=1;
            Bacillus clausii KSM-K16|Rep: Putative uncharacterized
            protein - Bacillus clausii (strain KSM-K16)
          Length = 1159

 Score = 34.7 bits (76), Expect = 4.3
 Identities = 17/57 (29%), Positives = 33/57 (57%), Gaps = 3/57 (5%)

Query: 308  MKYDPILPLKVALVNAISPAYPLGNLHWEGIEREATSDNVVIGVPTLEDLGVTLTHM 364
            + Y+ +L L   L+ AIS A+ +    WEG++ E T+ N   G+   ++L +T++ +
Sbjct: 1057 LAYELLLDLGETLLGAISCAFSIALAIWEGVDGEMTTSN---GMKLTQNLAITISQI 1110


>UniRef50_Q5FL85 Cluster: 3-oxoacyl-(Acyl-carrier protein)
          reductase; n=5; Lactobacillus|Rep:
          3-oxoacyl-(Acyl-carrier protein) reductase -
          Lactobacillus acidophilus
          Length = 242

 Score = 34.7 bits (76), Expect = 4.3
 Identities = 16/39 (41%), Positives = 21/39 (53%)

Query: 57 ATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRL 95
          A VFG TG +G+ +C  L + G  L L Y     +AQ L
Sbjct: 4  AIVFGATGGIGKAICQDLAEDGWSLYLHYNTKMQEAQHL 42


>UniRef50_Q489H0 Cluster: Pseudouridine synthase; n=1; Colwellia
           psychrerythraea 34H|Rep: Pseudouridine synthase -
           Colwellia psychrerythraea (strain 34H / ATCC BAA-681)
           (Vibriopsychroerythus)
          Length = 567

 Score = 34.7 bits (76), Expect = 4.3
 Identities = 19/50 (38%), Positives = 27/50 (54%), Gaps = 3/50 (6%)

Query: 68  RYVCN---KLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDE 114
           RYV     KL K   ++ LP RGDF D  +  VC + G+   T + L++E
Sbjct: 446 RYVATIEGKLEKTSGEICLPLRGDFDDRPKQMVCHEHGKYAETHWQLIEE 495


>UniRef50_Q1ARH9 Cluster: NmrA-like protein; n=1; Rubrobacter
           xylanophilus DSM 9941|Rep: NmrA-like protein -
           Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
          Length = 292

 Score = 34.7 bits (76), Expect = 4.3
 Identities = 25/68 (36%), Positives = 36/68 (52%), Gaps = 3/68 (4%)

Query: 196 ECAVREEYPTATIIRASDIYGSE-DRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSD 254
           E  VR      TI+R + IYGSE DR +  L+ +    S L P++ +G   + QPV+  D
Sbjct: 116 ERVVRSSGLEWTIVRPTMIYGSELDRNVHRLL-RFLDRSPLFPVFGSG-KNLWQPVYYED 173

Query: 255 VAQGIVNA 262
            A+G   A
Sbjct: 174 CARGAFEA 181


>UniRef50_A5V7D1 Cluster: Short-chain dehydrogenase/reductase SDR;
          n=1; Sphingomonas wittichii RW1|Rep: Short-chain
          dehydrogenase/reductase SDR - Sphingomonas wittichii
          RW1
          Length = 265

 Score = 34.7 bits (76), Expect = 4.3
 Identities = 15/33 (45%), Positives = 20/33 (60%)

Query: 56 VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGD 88
          VA V G +G +GR +C KL   GT + L YR +
Sbjct: 20 VALVIGGSGGIGRAICEKLAAAGTDVALTYRSN 52


>UniRef50_Q4QE34 Cluster: Putative uncharacterized protein; n=6;
           Trypanosomatidae|Rep: Putative uncharacterized protein -
           Leishmania major
          Length = 479

 Score = 34.7 bits (76), Expect = 4.3
 Identities = 30/109 (27%), Positives = 45/109 (41%), Gaps = 7/109 (6%)

Query: 113 DEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLN 172
           D   +  A   S+ +I  V    E  N  ++DV + G   ++   R    ER I  + L+
Sbjct: 152 DRIQVNVAANGSDTLIFAVDYHAEYANNSHHDVFLIGATNVSWTARSVRAERVIFCNGLD 211

Query: 173 AEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRF 221
           A            S +   +  GE AV   +P ATIIR   +YG   R+
Sbjct: 212 A-------TFASESNYVDFRARGEDAVGANHPDATIIRFGPLYGKNYRY 253


>UniRef50_UPI0000D9CF92 Cluster: PREDICTED: DNA polymerase epsilon
           catalytic subunit; n=1; Macaca mulatta|Rep: PREDICTED:
           DNA polymerase epsilon catalytic subunit - Macaca
           mulatta
          Length = 1460

 Score = 34.3 bits (75), Expect = 5.7
 Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 6/81 (7%)

Query: 156 ICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDI- 214
           ICR   ++RF+ L+Y   EE   P ++   S+W++ +   E  V EE+P   I  A  I 
Sbjct: 795 ICR--AIQRFL-LAY--KEERRGPTLIAVQSSWELKRLASEIPVLEEFPLVPICVADKIN 849

Query: 215 YGSEDRFLRSLVNKMRSHSNL 235
           YG  D         +R + NL
Sbjct: 850 YGVLDWQRHGARRMIRHYLNL 870


>UniRef50_Q896Q0 Cluster: Transcriptional regulator, merR family;
           n=10; Firmicutes|Rep: Transcriptional regulator, merR
           family - Clostridium tetani
          Length = 284

 Score = 34.3 bits (75), Expect = 5.7
 Identities = 19/61 (31%), Positives = 32/61 (52%), Gaps = 3/61 (4%)

Query: 292 KLMRKDEKWGGYIRYDMKYDPILPLKVALVNAISPAYPLGNLHWEGIEREATSDNVVIGV 351
           K +RKDE     ++Y++    +   +VA +  I P+Y +  + WE I +E  + NV  G 
Sbjct: 120 KRLRKDED---AMKYNVTLKEMPKRQVASLREIIPSYEMEGILWEEIRKEMDAQNVQFGN 176

Query: 352 P 352
           P
Sbjct: 177 P 177


>UniRef50_Q6MRE5 Cluster: Dihydroflavonol-4-reductase; n=2;
           Bdellovibrio bacteriovorus|Rep:
           Dihydroflavonol-4-reductase - Bdellovibrio bacteriovorus
          Length = 330

 Score = 34.3 bits (75), Expect = 5.7
 Identities = 51/223 (22%), Positives = 94/223 (42%), Gaps = 29/223 (13%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQL--ILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEES 116
           V G  GF+G ++   L + G  +  ++  + D  + + +K     G V        D  S
Sbjct: 6   VTGANGFLGSWLTKALLEEGHDVYALVRPKSDLSELEGVKCKYVHGDVT-------DVHS 58

Query: 117 IAKAVRYSNVVINLVGRDYETKNFK--YNDVHVDGVRRIARICREEGVERFIHLSYLNA- 173
           + +A +  + V +L G     K+ +   + V+V+G   +  +CRE  V R ++LS + A 
Sbjct: 59  LLEATKGMDTVFHLAGVIAYKKSQRALMDKVNVEGTANVIAVCREHNVRRLVYLSSVVAI 118

Query: 174 -EEHPKPLVLKKPSAWKI---------SKYLGECAVR----EEYPTATIIRASDIYGSED 219
              +    +L + S + I         +K+  E  V+    +    A ++  S IYG  D
Sbjct: 119 GAGYTPDQILNEESPYNIADLNLGYFETKHQAETLVKSACDKNEIDAVMLNPSTIYGRGD 178

Query: 220 RFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNA 262
               S   +++     +  Y +G   V   V   DV  GI++A
Sbjct: 179 AKKGSRKMQVKVAQGKLNFYTSGGVNV---VAAEDVVAGILSA 218


>UniRef50_Q2SJG1 Cluster: Nucleoside-diphosphate-sugar epimerase;
           n=1; Hahella chejuensis KCTC 2396|Rep:
           Nucleoside-diphosphate-sugar epimerase - Hahella
           chejuensis (strain KCTC 2396)
          Length = 305

 Score = 34.3 bits (75), Expect = 5.7
 Identities = 49/198 (24%), Positives = 85/198 (42%), Gaps = 26/198 (13%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           + GCTGFVG  +  +    G  +    R      Q        G++   P +  + +   
Sbjct: 5   ITGCTGFVGSALAAEAASRGYVVTGTSRSADQHPQFP------GKMELAPAY--ENDGWI 56

Query: 119 KAVRYSNVVINLVGRDYETKN------FKYNDVHVDGVRRIARICREEGVERFIHLSYL- 171
             +R  +V+I+   R ++ K        ++   + +  R +A    + GV++FI+LS + 
Sbjct: 57  GLLRGVDVLIHCAARVHQVKEDAAEPLAEFRAANTEATRLLASWAVKAGVKKFIYLSTIK 116

Query: 172 -NAE-EHP-KPLVLKKP----SAWKISKYLGECAVREEYPTA----TIIRASDIYGSEDR 220
            N E   P +P     P    S + ISK+ GECA+RE    A     IIR   +YG   +
Sbjct: 117 VNGEGSSPGRPFTPSDPPNPLSPYAISKWEGECALREVAAGAEMSYEIIRPPLVYGEGAK 176

Query: 221 FLRSLVNKMRSHSNLMPL 238
              +++ K+      +PL
Sbjct: 177 GNLAILEKLAKLRAPLPL 194


>UniRef50_Q8KNM3 Cluster: DTDP-6-deoxy-L-mannose-dehydrogenase; n=2;
           Aeromonas hydrophila|Rep:
           DTDP-6-deoxy-L-mannose-dehydrogenase - Aeromonas
           hydrophila
          Length = 300

 Score = 34.3 bits (75), Expect = 5.7
 Identities = 20/57 (35%), Positives = 32/57 (56%), Gaps = 6/57 (10%)

Query: 175 EHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDR-FLRSLVNKMR 230
           + P+PL     + + +SKY GE A++   P   IIR   +YG E R F R+++ + R
Sbjct: 119 DQPRPL-----NVYGMSKYAGELAIQRLCPHHLIIRTGWLYGGEGRHFARTILARAR 170


>UniRef50_Q2AZL1 Cluster: NAD-dependent epimerase/dehydratase:3-beta
           hydroxysteroid dehydrogenase/isomerase:Polysaccharide
           biosynthesis protein CapD:dTDP- 4-dehydrorhamnose
           reductase:Nucleotide sugar epimerase; n=3; Bacillus
           cereus group|Rep: NAD-dependent
           epimerase/dehydratase:3-beta hydroxysteroid
           dehydrogenase/isomerase:Polysaccharide biosynthesis
           protein CapD:dTDP- 4-dehydrorhamnose
           reductase:Nucleotide sugar epimerase - Bacillus
           weihenstephanensis KBAB4
          Length = 307

 Score = 34.3 bits (75), Expect = 5.7
 Identities = 54/219 (24%), Positives = 102/219 (46%), Gaps = 27/219 (12%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           V G  GF+G++V  +L   G ++I+      +D  + K   D   V F    +LD  ++ 
Sbjct: 5   VIGGGGFIGKHVTKELIARGYEVII------FD--KFKPSMD---VPFEEIDILDIATLR 53

Query: 119 KAVRYSNVVINL---VGRDYETKNFK-YNDVHVDGVRRIARICREEGVERFIHLS----Y 170
           + +   + VI+L   VG D    N +    V+ +G + I  +C E G+ + +  S    Y
Sbjct: 54  EKLINVDGVIHLAALVGVDNCRSNEEDVVRVNFEGTKNIVEVCIENGIGKLLFSSSSEVY 113

Query: 171 LNAEEHP-KPLVLKKP-SAWKISKYLGECAVREEYPTA---TIIRASDIYGSE--DRFLR 223
            +    P K   +K P SA+  +K + E  ++E    +    ++R  ++YGS+  + F+ 
Sbjct: 114 GDGVSVPFKENDVKIPKSAYGKAKLMSEDFLKEYANNSFKVRVVRYFNVYGSQQNENFVI 173

Query: 224 SLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNA 262
           S   K   +   M +Y +G   ++   ++SD+  G + A
Sbjct: 174 SKFLKQAHNGENMTIYGDG-QQIRCFSYISDIVNGTILA 211


>UniRef50_Q1J1X7 Cluster: E3 binding; n=1; Deinococcus geothermalis
           DSM 11300|Rep: E3 binding - Deinococcus geothermalis
           (strain DSM 11300)
          Length = 445

 Score = 34.3 bits (75), Expect = 5.7
 Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 2/63 (3%)

Query: 300 WGGYIRYDMKYDPILPLKVALVNAISPAYPLGNLHWEGIEREATSDNVVIGVPTLEDLGV 359
           +G Y+R D    P+  L+  L+ A+    PLG L     +R A  D + +    ++DLGV
Sbjct: 297 FGTYLRRDANLAPVTELRRQLIAALGQDVPLGLLVARAAQRHA--DRLGLNTVAVQDLGV 354

Query: 360 TLT 362
             T
Sbjct: 355 NQT 357


>UniRef50_Q048B8 Cluster: Glycerophosphoryl diester
           phosphodiesterase; n=2; Lactobacillus delbrueckii subsp.
           bulgaricus|Rep: Glycerophosphoryl diester
           phosphodiesterase - Lactobacillus delbrueckii subsp.
           bulgaricus (strain ATCC BAA-365)
          Length = 473

 Score = 34.3 bits (75), Expect = 5.7
 Identities = 16/44 (36%), Positives = 25/44 (56%)

Query: 138 KNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPLV 181
           K+  Y D+ V  +R+   IC++ G E F+ L Y+N  E  K +V
Sbjct: 308 KDKVYEDLRVPTLRQYLEICKKYGKEAFLELKYINNMEALKEVV 351


>UniRef50_A7FRZ5 Cluster: RNA polymerase sigma-70 factor family;
           n=12; Clostridium|Rep: RNA polymerase sigma-70 factor
           family - Clostridium botulinum (strain ATCC 19397 / Type
           A)
          Length = 179

 Score = 34.3 bits (75), Expect = 5.7
 Identities = 18/59 (30%), Positives = 36/59 (61%), Gaps = 3/59 (5%)

Query: 175 EHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIY-GSEDRFLRSLVNKMRSH 232
           E+  PL+LK+ S W+I  Y  E  V+  Y   ++I+A +++ G E +F+   +N ++++
Sbjct: 21  ENFNPLILKEASRWRIGGYEYEDLVQHGY--LSVIKAVNMFKGEESKFVPYCINAIKTN 77


>UniRef50_A4JR88 Cluster: NmrA family protein; n=2;
           Proteobacteria|Rep: NmrA family protein - Burkholderia
           vietnamiensis (strain G4 / LMG 22486)
           (Burkholderiacepacia (strain R1808))
          Length = 217

 Score = 34.3 bits (75), Expect = 5.7
 Identities = 35/156 (22%), Positives = 63/156 (40%), Gaps = 8/156 (5%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           +FG TG  GR++      I   L   Y+   Y     K+    G+V      L D+ +IA
Sbjct: 9   LFGATGPTGRHI------IEEALTQGYKLSVYTRDAKKLAPFAGRVEIVVGDLKDQRAIA 62

Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 178
           K V+ ++ VI+ +G +  +   + +   + G+  I    +  GV R I +S     +   
Sbjct: 63  KCVQGADAVISALGPN--SLKVQGDKPIMRGLTNIIAAMKRAGVRRLIQISTAAYRDPKD 120

Query: 179 PLVLKKPSAWKISKYLGECAVREEYPTATIIRASDI 214
               K  +   + K +      +   T  +I  SD+
Sbjct: 121 GFAFKAHAFALLFKVIASKGYEDIKATGELIANSDL 156


>UniRef50_A3TUE1 Cluster: Putative uncharacterized protein; n=3;
           Rhodobacteraceae|Rep: Putative uncharacterized protein -
           Oceanicola batsensis HTCC2597
          Length = 288

 Score = 34.3 bits (75), Expect = 5.7
 Identities = 26/116 (22%), Positives = 51/116 (43%), Gaps = 8/116 (6%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           V G TG++GR++C +  + G  +    R    DA+R +   D    +     +   E++ 
Sbjct: 5   VAGATGYLGRFLCAEYARRGHHVTALVR----DARRAEGLAD----VLVEAEVTRPETLR 56

Query: 119 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 174
             +   ++V++ +G   +     Y +V       + R     GV RF ++  LNA+
Sbjct: 57  GIMDGMDLVVSSLGITRQADGLGYLEVDFQANLNLLREAETAGVRRFAYVHVLNAD 112


>UniRef50_A1K6I8 Cluster: NADH dehydrogenase; n=3;
           Betaproteobacteria|Rep: NADH dehydrogenase - Azoarcus
           sp. (strain BH72)
          Length = 445

 Score = 34.3 bits (75), Expect = 5.7
 Identities = 55/225 (24%), Positives = 92/225 (40%), Gaps = 20/225 (8%)

Query: 37  PNLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLK 96
           P     K   GG  + N +V    G TGF+G  + ++L + G QL    R       R  
Sbjct: 5   PRAVCKKVQHGGVRTVNVLVT---GATGFLGGSIVDRLLREGHQLRCAVRDPVAAVARRP 61

Query: 97  VCGDLGQVLFT-PY-HLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIA 154
                G   F   Y H    ++  + +    VVIN VG   E  + +++ +H    R + 
Sbjct: 62  -----GPAYFPLDYRHATTADAWREMLVGVEVVINAVGILREQGDQRFDLLHRAAPRALF 116

Query: 155 RICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDI 214
             C E GV R + +S L A+           SA+ +SK   +  +      AT+++ S +
Sbjct: 117 DACVEAGVRRVLQISALGAD-------AGAASAYHLSKRAADDHLLALPLEATVVQPSLV 169

Query: 215 YGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGI 259
           +G       +L   + S   ++ L   G   + QPV V D+ + +
Sbjct: 170 FGGAGA-STALFASLAS-MPVVALPGGGRQRI-QPVHVDDLVEAV 211


>UniRef50_A1BFY1 Cluster: NAD-dependent epimerase/dehydratase; n=10;
           Chlorobiaceae|Rep: NAD-dependent epimerase/dehydratase -
           Chlorobium phaeobacteroides (strain DSM 266)
          Length = 238

 Score = 34.3 bits (75), Expect = 5.7
 Identities = 37/152 (24%), Positives = 66/152 (43%), Gaps = 7/152 (4%)

Query: 51  SFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYH 110
           +F G V  V G TG  G+++  +L +      L  R      + +++ G   +   +   
Sbjct: 4   TFKGTVLVV-GATGRTGQWIVRRLEEHHIPCHLFVRSS---EKAVELFGPEVEGHISTGS 59

Query: 111 LLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDV-HVDGVRRIARICREEGVERFIHLS 169
           + + E I  A+ +++ +I  +G            V   DGV R+A + +++ + +FI +S
Sbjct: 60  IENSEEIKSALEHADAIICAIGSSVTNPEEPPPSVIDRDGVIRLATLAKQKNIRKFILVS 119

Query: 170 YLNAEEHPKPLVLKKPSAWKISKYLGECAVRE 201
            L   +   P  L K       K  GE AVRE
Sbjct: 120 SLAVTKPDHP--LNKYGNVLTMKLAGEDAVRE 149


>UniRef50_A0NIS8 Cluster: NADH dehydrogenase; n=2; Oenococcus
           oeni|Rep: NADH dehydrogenase - Oenococcus oeni ATCC
           BAA-1163
          Length = 212

 Score = 34.3 bits (75), Expect = 5.7
 Identities = 47/216 (21%), Positives = 94/216 (43%), Gaps = 17/216 (7%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           VFG +GF+G+ +   L K G  +I   R    D+   K      ++ +    +L++    
Sbjct: 7   VFGGSGFIGQKLLEILVKRGHDIISVSRHGRPDSLTEKWA---DKITWVSSDILNDHEWQ 63

Query: 119 KAVRYSNVVINLVGRDYET--KNFKYNDVHVDGVRRIARICREEGVE-RFIHLSYLNAEE 175
           K V+ ++ +I+ VG  +E   KN  Y+   V  VR I    +    E RF+ +S      
Sbjct: 64  KYVKDADWIIDSVGILFENPKKNITYDRFIVQPVREITDFLKNNKSENRFLFIS-----A 118

Query: 176 HPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGS--EDRFLRSLVNKMRSHS 233
           +  P + +K   +  +KYL E   + +     I+    ++ S      + +L  ++ +H 
Sbjct: 119 NKGPFIFRK---YMEAKYLAEKITKRQNKNNLIVYPGLVFDSVKTSSIVITLPLRILNHI 175

Query: 234 NLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTK 269
            L+     G   +K+     ++++ I++  +   TK
Sbjct: 176 PLLNKVIIGYLPIKRVTLAKEISK-IIDGGQSIYTK 210


>UniRef50_Q4XFA1 Cluster: Putative uncharacterized protein; n=1;
          Plasmodium chabaudi|Rep: Putative uncharacterized
          protein - Plasmodium chabaudi
          Length = 61

 Score = 34.3 bits (75), Expect = 5.7
 Identities = 17/46 (36%), Positives = 25/46 (54%)

Query: 30 NYSSDRKPNLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLG 75
          NY S   PNL+  KR     SSF+ + A +  CT  +  ++ NK+G
Sbjct: 14 NYISIHHPNLSFLKRVENIASSFSILYAVICTCTSLIFPFLINKVG 59


>UniRef50_Q07864 Cluster: DNA polymerase epsilon catalytic subunit A;
            n=55; Eumetazoa|Rep: DNA polymerase epsilon catalytic
            subunit A - Homo sapiens (Human)
          Length = 2286

 Score = 34.3 bits (75), Expect = 5.7
 Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 6/81 (7%)

Query: 156  ICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDI- 214
            ICR   ++RF+ L+Y   EE   P ++   S+W++ +   E  V EE+P   I  A  I 
Sbjct: 1564 ICR--AIQRFL-LAY--KEERRGPTLIAVQSSWELKRLASEIPVLEEFPLVPICVADKIN 1618

Query: 215  YGSEDRFLRSLVNKMRSHSNL 235
            YG  D         +R + NL
Sbjct: 1619 YGVLDWQRHGARRMIRHYLNL 1639


>UniRef50_UPI0000E4A50F Cluster: PREDICTED: similar to Methionine
           adenosyltransferase II, beta; n=2; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to Methionine
           adenosyltransferase II, beta - Strongylocentrotus
           purpuratus
          Length = 231

 Score = 33.9 bits (74), Expect = 7.6
 Identities = 35/126 (27%), Positives = 53/126 (42%), Gaps = 6/126 (4%)

Query: 145 VHVDGVRRIARICREEGVER-FIHLSYLNAEEHP--KPLVLKKP-SAWKISKYLGECAVR 200
           ++V     IA +C + G+   +I  +Y+     P  KP     P + +  SK  GE A  
Sbjct: 35  LNVGATAVIASVCEKLGILLVYISTNYVFDGTKPPYKPSDAPNPLNKYGQSKRDGEIATL 94

Query: 201 EEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQ--PVFVSDVAQG 258
           E YP A I+R   +YGS +R   S    +             L   +Q  P  V DVA  
Sbjct: 95  EHYPGAVILRLPLLYGSIERLNESAATYLLHQIQDDTSKVQDLCDYQQRRPTHVRDVASV 154

Query: 259 IVNAAR 264
           ++  A+
Sbjct: 155 LLQLAQ 160


>UniRef50_Q7WAF7 Cluster: Putative oxidoreductase; n=3;
           Bordetella|Rep: Putative oxidoreductase - Bordetella
           parapertussis
          Length = 262

 Score = 33.9 bits (74), Expect = 7.6
 Identities = 20/70 (28%), Positives = 33/70 (47%), Gaps = 1/70 (1%)

Query: 54  GIVATVFGCTGFVGRYVCNKLGKIGTQL-ILPYRGDFYDAQRLKVCGDLGQVLFTPYHLL 112
           G VA + G  G +G     +    G  L +L  R D  +    ++CG  GQ +     + 
Sbjct: 16  GRVALITGAAGGIGSAAALRFAAEGAALALLDRRPDAIEQLAGRICGQGGQAIGVAADVT 75

Query: 113 DEESIAKAVR 122
           D++S+ +AVR
Sbjct: 76  DDDSVRQAVR 85


>UniRef50_Q7UXZ2 Cluster: 3-beta-hydroxysteroid dehydrogenase; n=2;
           Planctomycetaceae|Rep: 3-beta-hydroxysteroid
           dehydrogenase - Rhodopirellula baltica
          Length = 339

 Score = 33.9 bits (74), Expect = 7.6
 Identities = 29/112 (25%), Positives = 54/112 (48%), Gaps = 8/112 (7%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 118
           V GC+GF+G  +  +L +   +++   R +  D  R  +    G        LLD E +A
Sbjct: 6   VTGCSGFLGGEIVRQLLQRDCEVVGLSRRETADLVRAGMTHHRGD-------LLDTEYLA 58

Query: 119 KAVRYSNVVINLVGRDYETKNFK-YNDVHVDGVRRIARICREEGVERFIHLS 169
           + +  ++VVI+         +++ Y D +V   R + + C+E GV + I+ S
Sbjct: 59  RVIAGADVVIHTAAVAGVWGSWQHYFDNNVVASRNVLQACQELGVSQLIYTS 110


>UniRef50_A0LUB4 Cluster: Uncharacterised conserved protein
           UCP033563; n=1; Acidothermus cellulolyticus 11B|Rep:
           Uncharacterised conserved protein UCP033563 -
           Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
          Length = 426

 Score = 33.9 bits (74), Expect = 7.6
 Identities = 15/32 (46%), Positives = 23/32 (71%), Gaps = 3/32 (9%)

Query: 84  PYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 115
           P+RG  YDA R+   GD+G+VL  PY ++D++
Sbjct: 14  PFRGIRYDAARV---GDIGRVLAPPYDVIDDD 42


>UniRef50_Q3KN81 Cluster: Leucoanthocyanidin reductase; n=3;
           Spermatophyta|Rep: Leucoanthocyanidin reductase - Pinus
           taeda (Loblolly pine)
          Length = 359

 Score = 33.9 bits (74), Expect = 7.6
 Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 5/77 (6%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQR--LKVCGDLG-QVLFTPYHLLDEE 115
           + G TGF+GR+V     K G       R     ++   ++   D G QV++   H  D  
Sbjct: 62  IIGATGFIGRFVAEASVKSGRPTYALVRPTTLSSKPKVIQSLVDSGIQVVYGCLH--DHN 119

Query: 116 SIAKAVRYSNVVINLVG 132
           S+ KA+R  +VVI+ VG
Sbjct: 120 SLVKAIRQVDVVISTVG 136


>UniRef50_O22856 Cluster: Putative sterol dehydrogenase; n=1;
           Arabidopsis thaliana|Rep: Putative sterol dehydrogenase
           - Arabidopsis thaliana (Mouse-ear cress)
          Length = 561

 Score = 33.9 bits (74), Expect = 7.6
 Identities = 30/117 (25%), Positives = 49/117 (41%), Gaps = 6/117 (5%)

Query: 59  VFGCTGFVGRYVCNKLGKIGTQLI-LPYRGDFYDAQR----LKVCGDLGQVLFTPYHLLD 113
           V G  GF+GR + ++L ++G   + +   G           L+     G+  +    + D
Sbjct: 17  VLGGRGFIGRSLVSRLLRLGNWTVRVADSGHTLHLDESDSLLEDALSSGRASYHCVDVRD 76

Query: 114 EESIAKAVRYSNVVINLVGRDYETKN-FKYNDVHVDGVRRIARICREEGVERFIHLS 169
           +  I K    S VV  +   D  + + F    V V G R +   CRE GV + I+ S
Sbjct: 77  KPQIVKVTEGSYVVFYMGATDLRSHDYFDCYKVIVQGTRNVISACRESGVRKLIYNS 133


>UniRef50_Q178F4 Cluster: Mpv17 protein; n=5; Endopterygota|Rep:
           Mpv17 protein - Aedes aegypti (Yellowfever mosquito)
          Length = 226

 Score = 33.9 bits (74), Expect = 7.6
 Identities = 19/45 (42%), Positives = 27/45 (60%), Gaps = 2/45 (4%)

Query: 221 FLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARD 265
           FL+  V+++RS+ +L  LYK  L  VK PV V  V  GI+  + D
Sbjct: 14  FLKLPVSRIRSNMSLSSLYKRAL--VKYPVLVQSVQSGILMGSGD 56


>UniRef50_Q04304 Cluster: Uncharacterized protein YMR090W; n=5;
           Saccharomycetales|Rep: Uncharacterized protein YMR090W -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 227

 Score = 33.9 bits (74), Expect = 7.6
 Identities = 38/180 (21%), Positives = 75/180 (41%), Gaps = 7/180 (3%)

Query: 59  VFGCTGFVGRYVCNKL---GKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 115
           V G +G VGR + N+L       T L +    D  +  + +V  D      T        
Sbjct: 8   VVGASGKVGRLLINQLKANDSFSTPLAIVRTQDQVNYFKNEVGVDAS---LTDIENASVS 64

Query: 116 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 175
            I  A++  + V+   G   +     +  V +DG  ++   C + G++RF+ +S L AE+
Sbjct: 65  EITDAIKAYDAVVFSAGAGGKGMERIFT-VDLDGCIKVVEACEKAGIKRFVVVSALKAED 123

Query: 176 HPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVNKMRSHSNL 235
                 +K    + I+K   +  VR      TI++   +  ++   L   ++K+   +++
Sbjct: 124 RDFWYNIKGLREYYIAKRSADREVRNSNLDYTILQPGSLELNKGTGLLQPLDKLEEKASV 183


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.320    0.138    0.419 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 465,557,984
Number of Sequences: 1657284
Number of extensions: 20300059
Number of successful extensions: 42190
Number of sequences better than 10.0: 189
Number of HSP's better than 10.0 without gapping: 67
Number of HSP's successfully gapped in prelim test: 122
Number of HSP's that attempted gapping in prelim test: 41896
Number of HSP's gapped (non-prelim): 213
length of query: 399
length of database: 575,637,011
effective HSP length: 102
effective length of query: 297
effective length of database: 406,594,043
effective search space: 120758430771
effective search space used: 120758430771
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 74 (33.9 bits)

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