Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000897-TA|BGIBMGA000897-PA|IPR001509|NAD-dependent
epimerase/dehydratase
(399 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
L04490-1|AAA36350.1| 375|Homo sapiens NADH dehydrogenase (ubiqu... 255 2e-67
BC111546-1|AAI11547.1| 377|Homo sapiens NADH dehydrogenase (ubi... 255 2e-67
BC015837-1|AAH15837.1| 377|Homo sapiens NADH dehydrogenase (ubi... 255 2e-67
BC009311-1|AAH09311.1| 377|Homo sapiens NADH dehydrogenase (ubi... 255 2e-67
AF050641-1|AAD42055.1| 377|Homo sapiens NADH-ubiquinone oxidore... 255 2e-67
BC003351-1|AAH03351.1| 338|Homo sapiens Similar to NADH dehydro... 254 4e-67
BC111532-1|AAI11533.1| 706|Homo sapiens ZNF304 protein protein. 37 0.14
BC111531-1|AAI11532.1| 617|Homo sapiens ZNF304 protein protein. 37 0.14
AJ276316-1|CAC06610.1| 659|Homo sapiens zinc finger protein 304... 37 0.14
U49356-1|AAA90924.1| 2285|Homo sapiens DNA polymerase epsilon ca... 34 0.76
S60080-1|AAA15448.1| 2257|Homo sapiens DNA polymerase epsilon ca... 34 0.76
L09561-1|AAC19148.1| 2286|Homo sapiens DNA polymerase epsilon, c... 34 0.76
BC087613-1|AAH87613.1| 797|Homo sapiens POLE protein protein. 34 0.76
BC007599-1|AAH07599.1| 797|Homo sapiens Unknown (protein for IM... 34 0.76
AY273166-1|AAP12650.1| 2265|Homo sapiens polymerase (DNA directe... 34 0.76
AF127975-3|AAD44692.1| 2243|Homo sapiens DNA polymerase epsilon ... 34 0.76
AF127975-2|AAD44691.1| 2286|Homo sapiens DNA polymerase epsilon ... 34 0.76
AF127975-1|AAD44690.1| 2297|Homo sapiens DNA polymerase epsilon ... 34 0.76
U47105-1|AAC50558.2| 373|Homo sapiens H105e3 protein. 32 4.1
BC007816-1|AAH07816.1| 373|Homo sapiens NAD(P) dependent steroi... 32 4.1
BC000245-1|AAH00245.1| 373|Homo sapiens NAD(P) dependent steroi... 32 4.1
L04288-1|AAA35734.2| 1462|Homo sapiens cyclophilin-related prote... 31 7.1
BX957215-1|CAF29506.1| 1162|Homo sapiens hypothetical protein pr... 31 7.1
AF184110-1|AAD56402.1| 1462|Homo sapiens cyclophilin-related pro... 31 7.1
>L04490-1|AAA36350.1| 375|Homo sapiens NADH dehydrogenase
(ubiquinone) protein.
Length = 375
Score = 255 bits (624), Expect = 2e-67
Identities = 148/347 (42%), Positives = 215/347 (61%), Gaps = 20/347 (5%)
Query: 35 RKPNLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQR 94
R+ + A G GGRSS +GIVATVFG TGF+GRYV N LG++G+Q+I+PYR D YD
Sbjct: 32 RQLHHALMPHGKGGRSSVSGIVATVFGATGFLGRYVVNHLGRMGSQVIIPYRCDKYDIMH 91
Query: 95 LKVCGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIA 154
L+ GDLGQ+LF + D++SI + V++SNVVINL+GRD+ETKNF + DV V + IA
Sbjct: 92 LRPMGDLGQLLFLEWDARDKDSIRRVVQHSNVVINLIGRDWETKNFDFEDVFVKIPQAIA 151
Query: 155 RICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDI 214
++ +E GVE+FIH+S+LNA +K S + +K +GE VR+ +P A I++ SDI
Sbjct: 152 QLSKEAGVEKFIHVSHLNAN-------IKSSSRYLRNKAVGEKVVRDAFPEAIIVKPSDI 204
Query: 215 YGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQ 274
+G EDRFL S + R +PL G TVKQPV+V DV++GIVNA +D D + +
Sbjct: 205 FGREDRFLNSFASMHR--FGPIPLGSLGWKTVKQPVYVVDVSKGIVNAVKDPDANGKSFA 262
Query: 275 AVGPKRYLLADLVDWFYKLMRKDEKWGGYIRYDMKYDPILPLK-VALVNAISPAYPLGNL 333
VGP RYLL LV + + + + ++ + + P+ + VA V ISP P +
Sbjct: 263 FVGPSRYLLFHLVKYIFAVAHR-----LFLPFPL---PLFAYRWVARVFEISPFEPW--I 312
Query: 334 HWEGIEREATSDNVVIGVPTLEDLGVTLTHMEDQVPWELKPFRAHQY 380
+ +ER +D + +P LEDLG+ T +E + L+ R +++
Sbjct: 313 TRDKVERMHITDMKLPHLPGLEDLGIQATPLELKAIEVLRRHRTYRW 359
>BC111546-1|AAI11547.1| 377|Homo sapiens NADH dehydrogenase
(ubiquinone) 1 alpha subcomplex, 9, 39kDa protein.
Length = 377
Score = 255 bits (624), Expect = 2e-67
Identities = 148/347 (42%), Positives = 215/347 (61%), Gaps = 20/347 (5%)
Query: 35 RKPNLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQR 94
R+ + A G GGRSS +GIVATVFG TGF+GRYV N LG++G+Q+I+PYR D YD
Sbjct: 34 RQLHHALMPHGKGGRSSVSGIVATVFGATGFLGRYVVNHLGRMGSQVIIPYRCDKYDIMH 93
Query: 95 LKVCGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIA 154
L+ GDLGQ+LF + D++SI + V++SNVVINL+GRD+ETKNF + DV V + IA
Sbjct: 94 LRPMGDLGQLLFLEWDARDKDSIRRVVQHSNVVINLIGRDWETKNFDFEDVFVKIPQAIA 153
Query: 155 RICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDI 214
++ +E GVE+FIH+S+LNA +K S + +K +GE VR+ +P A I++ SDI
Sbjct: 154 QLSKEAGVEKFIHVSHLNAN-------IKSSSRYLRNKAVGEKVVRDAFPEAIIVKPSDI 206
Query: 215 YGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQ 274
+G EDRFL S + R +PL G TVKQPV+V DV++GIVNA +D D + +
Sbjct: 207 FGREDRFLNSFASMHR--FGPIPLGSLGWKTVKQPVYVVDVSKGIVNAVKDPDANGKSFA 264
Query: 275 AVGPKRYLLADLVDWFYKLMRKDEKWGGYIRYDMKYDPILPLK-VALVNAISPAYPLGNL 333
VGP RYLL LV + + + + ++ + + P+ + VA V ISP P +
Sbjct: 265 FVGPSRYLLFHLVKYIFAVAHR-----LFLPFPL---PLFAYRWVARVFEISPFEPW--I 314
Query: 334 HWEGIEREATSDNVVIGVPTLEDLGVTLTHMEDQVPWELKPFRAHQY 380
+ +ER +D + +P LEDLG+ T +E + L+ R +++
Sbjct: 315 TRDKVERMHITDMKLPHLPGLEDLGIQATPLELKAIEVLRRHRTYRW 361
>BC015837-1|AAH15837.1| 377|Homo sapiens NADH dehydrogenase
(ubiquinone) 1 alpha subcomplex, 9, 39kDa protein.
Length = 377
Score = 255 bits (624), Expect = 2e-67
Identities = 148/347 (42%), Positives = 215/347 (61%), Gaps = 20/347 (5%)
Query: 35 RKPNLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQR 94
R+ + A G GGRSS +GIVATVFG TGF+GRYV N LG++G+Q+I+PYR D YD
Sbjct: 34 RQLHHALMPHGKGGRSSVSGIVATVFGATGFLGRYVVNHLGRMGSQVIIPYRCDKYDIMH 93
Query: 95 LKVCGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIA 154
L+ GDLGQ+LF + D++SI + V++SNVVINL+GRD+ETKNF + DV V + IA
Sbjct: 94 LRPMGDLGQLLFLEWDARDKDSIRRVVQHSNVVINLIGRDWETKNFDFEDVFVKIPQAIA 153
Query: 155 RICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDI 214
++ +E GVE+FIH+S+LNA +K S + +K +GE VR+ +P A I++ SDI
Sbjct: 154 QLSKEAGVEKFIHVSHLNAN-------IKSSSRYLRNKAVGEKVVRDAFPEAIIVKPSDI 206
Query: 215 YGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQ 274
+G EDRFL S + R +PL G TVKQPV+V DV++GIVNA +D D + +
Sbjct: 207 FGREDRFLNSFASMHR--FGPIPLGSLGWKTVKQPVYVVDVSKGIVNAVKDPDANGKSFA 264
Query: 275 AVGPKRYLLADLVDWFYKLMRKDEKWGGYIRYDMKYDPILPLK-VALVNAISPAYPLGNL 333
VGP RYLL LV + + + + ++ + + P+ + VA V ISP P +
Sbjct: 265 FVGPSRYLLFHLVKYIFAVAHR-----LFLPFPL---PLFAYRWVARVFEISPFEPW--I 314
Query: 334 HWEGIEREATSDNVVIGVPTLEDLGVTLTHMEDQVPWELKPFRAHQY 380
+ +ER +D + +P LEDLG+ T +E + L+ R +++
Sbjct: 315 TRDKVERMHITDMKLPHLPGLEDLGIQATPLELKAIEVLRRHRTYRW 361
>BC009311-1|AAH09311.1| 377|Homo sapiens NADH dehydrogenase
(ubiquinone) 1 alpha subcomplex, 9, 39kDa protein.
Length = 377
Score = 255 bits (624), Expect = 2e-67
Identities = 148/347 (42%), Positives = 215/347 (61%), Gaps = 20/347 (5%)
Query: 35 RKPNLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQR 94
R+ + A G GGRSS +GIVATVFG TGF+GRYV N LG++G+Q+I+PYR D YD
Sbjct: 34 RQLHHALMPHGKGGRSSVSGIVATVFGATGFLGRYVVNHLGRMGSQVIIPYRCDKYDIMH 93
Query: 95 LKVCGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIA 154
L+ GDLGQ+LF + D++SI + V++SNVVINL+GRD+ETKNF + DV V + IA
Sbjct: 94 LRPMGDLGQLLFLEWDARDKDSIRRVVQHSNVVINLIGRDWETKNFDFEDVFVKIPQAIA 153
Query: 155 RICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDI 214
++ +E GVE+FIH+S+LNA +K S + +K +GE VR+ +P A I++ SDI
Sbjct: 154 QLSKEAGVEKFIHVSHLNAN-------IKSSSRYLRNKAVGEKVVRDAFPEAIIVKPSDI 206
Query: 215 YGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQ 274
+G EDRFL S + R +PL G TVKQPV+V DV++GIVNA +D D + +
Sbjct: 207 FGREDRFLNSFASMHR--FGPIPLGSLGWKTVKQPVYVVDVSKGIVNAVKDPDANGKSFA 264
Query: 275 AVGPKRYLLADLVDWFYKLMRKDEKWGGYIRYDMKYDPILPLK-VALVNAISPAYPLGNL 333
VGP RYLL LV + + + + ++ + + P+ + VA V ISP P +
Sbjct: 265 FVGPSRYLLFHLVKYIFAVAHR-----LFLPFPL---PLFAYRWVARVFEISPFEPW--I 314
Query: 334 HWEGIEREATSDNVVIGVPTLEDLGVTLTHMEDQVPWELKPFRAHQY 380
+ +ER +D + +P LEDLG+ T +E + L+ R +++
Sbjct: 315 TRDKVERMHITDMKLPHLPGLEDLGIQATPLELKAIEVLRRHRTYRW 361
>AF050641-1|AAD42055.1| 377|Homo sapiens NADH-ubiquinone
oxidoreductase 39kDa subunit protein.
Length = 377
Score = 255 bits (624), Expect = 2e-67
Identities = 148/347 (42%), Positives = 215/347 (61%), Gaps = 20/347 (5%)
Query: 35 RKPNLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQR 94
R+ + A G GGRSS +GIVATVFG TGF+GRYV N LG++G+Q+I+PYR D YD
Sbjct: 34 RQLHHALMPHGKGGRSSVSGIVATVFGATGFLGRYVVNHLGRMGSQVIIPYRCDKYDIMH 93
Query: 95 LKVCGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIA 154
L+ GDLGQ+LF + D++SI + V++SNVVINL+GRD+ETKNF + DV V + IA
Sbjct: 94 LRPMGDLGQLLFLEWDARDKDSIRRVVQHSNVVINLIGRDWETKNFDFEDVFVKIPQAIA 153
Query: 155 RICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDI 214
++ +E GVE+FIH+S+LNA +K S + +K +GE VR+ +P A I++ SDI
Sbjct: 154 QLSKEAGVEKFIHVSHLNAN-------IKSSSRYLRNKAVGEKVVRDAFPEAIIVKPSDI 206
Query: 215 YGSEDRFLRSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQ 274
+G EDRFL S + R +PL G TVKQPV+V DV++GIVNA +D D + +
Sbjct: 207 FGREDRFLNSFASMHR--FGPIPLGSLGWKTVKQPVYVVDVSKGIVNAVKDPDANGKSFA 264
Query: 275 AVGPKRYLLADLVDWFYKLMRKDEKWGGYIRYDMKYDPILPLK-VALVNAISPAYPLGNL 333
VGP RYLL LV + + + + ++ + + P+ + VA V ISP P +
Sbjct: 265 FVGPSRYLLFHLVKYIFAVAHR-----LFLPFPL---PLFAYRWVARVFEISPFEPW--I 314
Query: 334 HWEGIEREATSDNVVIGVPTLEDLGVTLTHMEDQVPWELKPFRAHQY 380
+ +ER +D + +P LEDLG+ T +E + L+ R +++
Sbjct: 315 TRDKVERMHITDMKLPHLPGLEDLGIQATPLELKAIEVLRRHRTYRW 361
>BC003351-1|AAH03351.1| 338|Homo sapiens Similar to NADH
dehydrogenase (ubiquinone) 1 alpha subcomplex, 9 (39kD)
protein.
Length = 338
Score = 254 bits (622), Expect = 4e-67
Identities = 146/337 (43%), Positives = 211/337 (62%), Gaps = 20/337 (5%)
Query: 45 GTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQV 104
G GGRSS +GIVATVFG TGF+GRYV N LG++G+Q+I+PYR D YD L+ GDLGQ+
Sbjct: 5 GKGGRSSVSGIVATVFGATGFLGRYVVNHLGRMGSQVIIPYRCDKYDIMHLRPMGDLGQL 64
Query: 105 LFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVER 164
LF + D++SI + V++SNVVINL+GRD+ETKNF + DV V + IA++ +E GVE+
Sbjct: 65 LFLEWDARDKDSIRRVVQHSNVVINLIGRDWETKNFDFEDVFVKIPQAIAQLSKEAGVEK 124
Query: 165 FIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRS 224
FIH+S+LNA +K S + +K +GE VR+ +P A I++ SDI+G EDRFL S
Sbjct: 125 FIHVSHLNAN-------IKSSSRYLRNKAVGEKVVRDAFPEAIIVKPSDIFGREDRFLNS 177
Query: 225 LVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAARDDDTKCEVYQAVGPKRYLLA 284
+ R +PL G TVKQPV+V DV++GIVNA +D D + + VGP RYLL
Sbjct: 178 FASMHR--FGPIPLGSLGWKTVKQPVYVVDVSKGIVNAVKDPDANGKSFAFVGPSRYLLF 235
Query: 285 DLVDWFYKLMRKDEKWGGYIRYDMKYDPILPLK-VALVNAISPAYPLGNLHWEGIEREAT 343
LV + + + + ++ + + P+ + VA V ISP P + + +ER
Sbjct: 236 HLVKYIFAVAHR-----LFLPFPL---PLFAYRWVARVFEISPFEPW--ITRDKVERMHI 285
Query: 344 SDNVVIGVPTLEDLGVTLTHMEDQVPWELKPFRAHQY 380
+D + +P LEDLG+ T +E + L+ R +++
Sbjct: 286 TDMKLPHLPGLEDLGIQATPLELKAIEVLRRHRTYRW 322
>BC111532-1|AAI11533.1| 706|Homo sapiens ZNF304 protein protein.
Length = 706
Score = 36.7 bits (81), Expect = 0.14
Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 5/91 (5%)
Query: 85 YRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYND 144
++GD YD Q L CGD G+ + LLD + VR + G ++ K+ N
Sbjct: 260 HQGD-YDGQMLFSCGDEGKAFLDTFTLLDSQMTHAEVRPFRCL--PCGNVFKEKSALINH 316
Query: 145 VHVDGVRRIARICREEGVERFIHLSYLNAEE 175
+ I+ +C+E G + FIHL +L +
Sbjct: 317 RKIHS-GEISHVCKECG-KAFIHLHHLKMHQ 345
>BC111531-1|AAI11532.1| 617|Homo sapiens ZNF304 protein protein.
Length = 617
Score = 36.7 bits (81), Expect = 0.14
Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 5/91 (5%)
Query: 85 YRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYND 144
++GD YD Q L CGD G+ + LLD + VR + G ++ K+ N
Sbjct: 171 HQGD-YDGQMLFSCGDEGKAFLDTFTLLDSQMTHAEVRPFRCL--PCGNVFKEKSALINH 227
Query: 145 VHVDGVRRIARICREEGVERFIHLSYLNAEE 175
+ I+ +C+E G + FIHL +L +
Sbjct: 228 RKIHS-GEISHVCKECG-KAFIHLHHLKMHQ 256
>AJ276316-1|CAC06610.1| 659|Homo sapiens zinc finger protein 304
protein.
Length = 659
Score = 36.7 bits (81), Expect = 0.14
Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 5/91 (5%)
Query: 85 YRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYND 144
++GD YD Q L CGD G+ + LLD + VR + G ++ K+ N
Sbjct: 213 HQGD-YDGQMLFSCGDEGKAFLDTFTLLDSQMTHAEVRPFRCL--PCGNVFKEKSALINH 269
Query: 145 VHVDGVRRIARICREEGVERFIHLSYLNAEE 175
+ I+ +C+E G + FIHL +L +
Sbjct: 270 RKIHS-GEISHVCKECG-KAFIHLHHLKMHQ 298
>U49356-1|AAA90924.1| 2285|Homo sapiens DNA polymerase epsilon
catalytic subunit protein.
Length = 2285
Score = 34.3 bits (75), Expect = 0.76
Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 6/81 (7%)
Query: 156 ICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDI- 214
ICR ++RF+ L+Y EE P ++ S+W++ + E V EE+P I A I
Sbjct: 1563 ICR--AIQRFL-LAY--KEERRGPTLIAVQSSWELKRLASEIPVLEEFPLVPICVADKIN 1617
Query: 215 YGSEDRFLRSLVNKMRSHSNL 235
YG D +R + NL
Sbjct: 1618 YGVLDWQRHGARRMIRHYLNL 1638
>S60080-1|AAA15448.1| 2257|Homo sapiens DNA polymerase epsilon
catalytic subunit protein.
Length = 2257
Score = 34.3 bits (75), Expect = 0.76
Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 6/81 (7%)
Query: 156 ICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDI- 214
ICR ++RF+ L+Y EE P ++ S+W++ + E V EE+P I A I
Sbjct: 1535 ICR--AIQRFL-LAY--KEERRGPTLIAVQSSWELKRLASEIPVLEEFPLVPICVADKIN 1589
Query: 215 YGSEDRFLRSLVNKMRSHSNL 235
YG D +R + NL
Sbjct: 1590 YGVLDWQRHGARRMIRHYLNL 1610
>L09561-1|AAC19148.1| 2286|Homo sapiens DNA polymerase epsilon,
catalytic polypeptide protein.
Length = 2286
Score = 34.3 bits (75), Expect = 0.76
Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 6/81 (7%)
Query: 156 ICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDI- 214
ICR ++RF+ L+Y EE P ++ S+W++ + E V EE+P I A I
Sbjct: 1564 ICR--AIQRFL-LAY--KEERRGPTLIAVQSSWELKRLASEIPVLEEFPLVPICVADKIN 1618
Query: 215 YGSEDRFLRSLVNKMRSHSNL 235
YG D +R + NL
Sbjct: 1619 YGVLDWQRHGARRMIRHYLNL 1639
>BC087613-1|AAH87613.1| 797|Homo sapiens POLE protein protein.
Length = 797
Score = 34.3 bits (75), Expect = 0.76
Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 6/81 (7%)
Query: 156 ICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDI- 214
ICR ++RF+ L+Y EE P ++ S+W++ + E V EE+P I A I
Sbjct: 75 ICR--AIQRFL-LAY--KEERRGPTLIAVQSSWELKRLASEIPVLEEFPLVPICVADKIN 129
Query: 215 YGSEDRFLRSLVNKMRSHSNL 235
YG D +R + NL
Sbjct: 130 YGVLDWQRHGARRMIRHYLNL 150
>BC007599-1|AAH07599.1| 797|Homo sapiens Unknown (protein for
IMAGE:3347229) protein.
Length = 797
Score = 34.3 bits (75), Expect = 0.76
Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 6/81 (7%)
Query: 156 ICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDI- 214
ICR ++RF+ L+Y EE P ++ S+W++ + E V EE+P I A I
Sbjct: 75 ICR--AIQRFL-LAY--KEERRGPTLIAVQSSWELKRLASEIPVLEEFPLVPICVADKIN 129
Query: 215 YGSEDRFLRSLVNKMRSHSNL 235
YG D +R + NL
Sbjct: 130 YGVLDWQRHGARRMIRHYLNL 150
>AY273166-1|AAP12650.1| 2265|Homo sapiens polymerase (DNA directed),
epsilon protein.
Length = 2265
Score = 34.3 bits (75), Expect = 0.76
Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 6/81 (7%)
Query: 156 ICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDI- 214
ICR ++RF+ L+Y EE P ++ S+W++ + E V EE+P I A I
Sbjct: 1543 ICR--AIQRFL-LAY--KEERRGPTLIAVQSSWELKRLASEIPVLEEFPLVPICVADKIN 1597
Query: 215 YGSEDRFLRSLVNKMRSHSNL 235
YG D +R + NL
Sbjct: 1598 YGVLDWQRHGARRMIRHYLNL 1618
>AF127975-3|AAD44692.1| 2243|Homo sapiens DNA polymerase epsilon
catalytic subunit protein isoform c protein.
Length = 2243
Score = 34.3 bits (75), Expect = 0.76
Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 6/81 (7%)
Query: 156 ICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDI- 214
ICR ++RF+ L+Y EE P ++ S+W++ + E V EE+P I A I
Sbjct: 1521 ICR--AIQRFL-LAY--KEERRGPTLIAVQSSWELKRLASEIPVLEEFPLVPICVADKIN 1575
Query: 215 YGSEDRFLRSLVNKMRSHSNL 235
YG D +R + NL
Sbjct: 1576 YGVLDWQRHGARRMIRHYLNL 1596
>AF127975-2|AAD44691.1| 2286|Homo sapiens DNA polymerase epsilon
catalytic subunit protein isoform b protein.
Length = 2286
Score = 34.3 bits (75), Expect = 0.76
Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 6/81 (7%)
Query: 156 ICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDI- 214
ICR ++RF+ L+Y EE P ++ S+W++ + E V EE+P I A I
Sbjct: 1564 ICR--AIQRFL-LAY--KEERRGPTLIAVQSSWELKRLASEIPVLEEFPLVPICVADKIN 1618
Query: 215 YGSEDRFLRSLVNKMRSHSNL 235
YG D +R + NL
Sbjct: 1619 YGVLDWQRHGARRMIRHYLNL 1639
>AF127975-1|AAD44690.1| 2297|Homo sapiens DNA polymerase epsilon
catalytic subunit protein isoform a protein.
Length = 2297
Score = 34.3 bits (75), Expect = 0.76
Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 6/81 (7%)
Query: 156 ICREEGVERFIHLSYLNAEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDI- 214
ICR ++RF+ L+Y EE P ++ S+W++ + E V EE+P I A I
Sbjct: 1575 ICR--AIQRFL-LAY--KEERRGPTLIAVQSSWELKRLASEIPVLEEFPLVPICVADKIN 1629
Query: 215 YGSEDRFLRSLVNKMRSHSNL 235
YG D +R + NL
Sbjct: 1630 YGVLDWQRHGARRMIRHYLNL 1650
>U47105-1|AAC50558.2| 373|Homo sapiens H105e3 protein.
Length = 373
Score = 31.9 bits (69), Expect = 4.1
Identities = 52/221 (23%), Positives = 89/221 (40%), Gaps = 25/221 (11%)
Query: 58 TVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 117
TV G +GF+G+++ +L L Y + +D Q+ D QV F L + +
Sbjct: 41 TVIGGSGFLGQHMVEQL------LARGYAVNVFDIQQ---GFDNPQVRFFLGDLCSRQDL 91
Query: 118 AKAVRYSNVVINLVGRDYETKNFK-YNDVHVDGVRRIARICREEGVERFIHLSY------ 170
A++ N V + + N + + V+ G + + C+E GV++ I S
Sbjct: 92 YPALKGVNTVFHCASPPPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVIFE 151
Query: 171 ---LNAEEHPKPLVLKKPSAWKISKYLGECAV-----REEYPTATIIRASDIYGSEDRFL 222
+ P +K + +K L E AV E+ T IR I+G D L
Sbjct: 152 GVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPEKNFLTTAIRPHGIFGPRDPQL 211
Query: 223 RSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAA 263
++ + + + + NG V FV +V G + AA
Sbjct: 212 VPILIEAARNGKMKFVIGNGKNLV-DFTFVENVVHGHILAA 251
>BC007816-1|AAH07816.1| 373|Homo sapiens NAD(P) dependent steroid
dehydrogenase-like protein.
Length = 373
Score = 31.9 bits (69), Expect = 4.1
Identities = 52/221 (23%), Positives = 89/221 (40%), Gaps = 25/221 (11%)
Query: 58 TVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 117
TV G +GF+G+++ +L L Y + +D Q+ D QV F L + +
Sbjct: 41 TVIGGSGFLGQHMVEQL------LARGYAVNVFDIQQ---GFDNPQVRFFLGDLCSRQDL 91
Query: 118 AKAVRYSNVVINLVGRDYETKNFK-YNDVHVDGVRRIARICREEGVERFIHLSY------ 170
A++ N V + + N + + V+ G + + C+E GV++ I S
Sbjct: 92 YPALKGVNTVFHCASPPPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVIFE 151
Query: 171 ---LNAEEHPKPLVLKKPSAWKISKYLGECAV-----REEYPTATIIRASDIYGSEDRFL 222
+ P +K + +K L E AV E+ T IR I+G D L
Sbjct: 152 GVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPEKNFLTTAIRPHGIFGPRDPQL 211
Query: 223 RSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAA 263
++ + + + + NG V FV +V G + AA
Sbjct: 212 VPILIEAARNGKMKFVIGNGKNLV-DFTFVENVVHGHILAA 251
>BC000245-1|AAH00245.1| 373|Homo sapiens NAD(P) dependent steroid
dehydrogenase-like protein.
Length = 373
Score = 31.9 bits (69), Expect = 4.1
Identities = 52/221 (23%), Positives = 89/221 (40%), Gaps = 25/221 (11%)
Query: 58 TVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 117
TV G +GF+G+++ +L L Y + +D Q+ D QV F L + +
Sbjct: 41 TVIGGSGFLGQHMVEQL------LARGYAVNVFDIQQ---GFDNPQVRFFLGDLCSRQDL 91
Query: 118 AKAVRYSNVVINLVGRDYETKNFK-YNDVHVDGVRRIARICREEGVERFIHLSY------ 170
A++ N V + + N + + V+ G + + C+E GV++ I S
Sbjct: 92 YPALKGVNTVFHCASPPPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVIFE 151
Query: 171 ---LNAEEHPKPLVLKKPSAWKISKYLGECAV-----REEYPTATIIRASDIYGSEDRFL 222
+ P +K + +K L E AV E+ T IR I+G D L
Sbjct: 152 GVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPEKNFLTTAIRPHGIFGPRDPQL 211
Query: 223 RSLVNKMRSHSNLMPLYKNGLATVKQPVFVSDVAQGIVNAA 263
++ + + + + NG V FV +V G + AA
Sbjct: 212 VPILIEAARNGKMKFVIGNGKNLV-DFTFVENVVHGHILAA 251
>L04288-1|AAA35734.2| 1462|Homo sapiens cyclophilin-related protein
protein.
Length = 1462
Score = 31.1 bits (67), Expect = 7.1
Identities = 17/55 (30%), Positives = 32/55 (58%), Gaps = 1/55 (1%)
Query: 173 AEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVN 227
A EHP+ V+K+ S+ SK LGE +++ +A++ A + G ++ +S +N
Sbjct: 1167 ATEHPQAEVVKQESSMSESKVLGEVG-KQDSSSASLASAGESTGKKEVAEKSQIN 1220
>BX957215-1|CAF29506.1| 1162|Homo sapiens hypothetical protein
protein.
Length = 1162
Score = 31.1 bits (67), Expect = 7.1
Identities = 17/55 (30%), Positives = 32/55 (58%), Gaps = 1/55 (1%)
Query: 173 AEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVN 227
A EHP+ V+K+ S+ SK LGE +++ +A++ A + G ++ +S +N
Sbjct: 867 ATEHPQAEVVKQESSMSESKVLGEVG-KQDSSSASLASAGESTGKKEVAEKSQIN 920
>AF184110-1|AAD56402.1| 1462|Homo sapiens cyclophilin-related protein
protein.
Length = 1462
Score = 31.1 bits (67), Expect = 7.1
Identities = 17/55 (30%), Positives = 32/55 (58%), Gaps = 1/55 (1%)
Query: 173 AEEHPKPLVLKKPSAWKISKYLGECAVREEYPTATIIRASDIYGSEDRFLRSLVN 227
A EHP+ V+K+ S+ SK LGE +++ +A++ A + G ++ +S +N
Sbjct: 1167 ATEHPQAEVVKQESSMSESKVLGEVG-KQDSSSASLASAGESTGKKEVAEKSQIN 1220
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.320 0.138 0.419
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 60,605,586
Number of Sequences: 224733
Number of extensions: 2682400
Number of successful extensions: 4170
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 4146
Number of HSP's gapped (non-prelim): 24
length of query: 399
length of database: 73,234,838
effective HSP length: 92
effective length of query: 307
effective length of database: 52,559,402
effective search space: 16135736414
effective search space used: 16135736414
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 66 (30.7 bits)
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