Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000895-TA|BGIBMGA000895-PA|IPR009053|Prefoldin
(706 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein p... 77 3e-13
Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein. 75 7e-13
BC046212-1|AAH46212.1| 364|Homo sapiens Similar to cytomatrix p... 70 3e-11
BC112391-1|AAI12392.1| 957|Homo sapiens ELKS/RAB6-interacting/C... 69 6e-11
BC111550-1|AAI11551.1| 957|Homo sapiens ERC2 protein protein. 69 6e-11
AB002376-1|BAA20832.2| 970|Homo sapiens KIAA0378 protein. 69 6e-11
X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein. 66 3e-10
X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein. 66 4e-10
U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein. 66 4e-10
U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein. 66 4e-10
L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated prote... 66 4e-10
BC132784-1|AAI32785.1| 1116|Homo sapiens ELKS/RAB6-interacting/C... 65 7e-10
BC132782-1|AAI32783.1| 1116|Homo sapiens ELKS/RAB6-interacting/C... 65 7e-10
AB053471-1|BAC54110.1| 1116|Homo sapiens ELKS epsilon protein. 65 7e-10
M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein. 62 7e-09
BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,... 62 7e-09
AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein p... 62 7e-09
AB209693-1|BAD92930.1| 1310|Homo sapiens golgi autoantigen, golg... 62 9e-09
AB053470-1|BAC54109.1| 1088|Homo sapiens ELKS delta protein. 62 9e-09
BC118918-1|AAI18919.1| 1302|Homo sapiens cingulin-like 1 protein. 61 1e-08
BC112049-1|AAI12050.1| 1302|Homo sapiens cingulin-like 1 protein. 61 1e-08
BC093827-1|AAH93827.1| 1302|Homo sapiens cingulin-like 1 protein. 61 1e-08
AY274808-1|AAP42073.1| 1302|Homo sapiens KIAA1749 protein protein. 61 1e-08
AB051536-1|BAB21840.2| 1047|Homo sapiens KIAA1749 protein protein. 61 1e-08
AB002334-1|BAA20794.2| 1635|Homo sapiens KIAA0336 protein. 60 3e-08
BC011621-1|AAH11621.1| 728|Homo sapiens hook homolog 1 (Drosoph... 60 3e-08
AL035416-6|CAI22779.1| 728|Homo sapiens hook homolog 1 (Drosoph... 60 3e-08
AF044923-1|AAC09298.1| 728|Homo sapiens hook1 protein protein. 60 3e-08
M77830-1|AAA85135.1| 2871|Homo sapiens desmoplakin I protein. 59 5e-08
J05211-1|AAA35766.1| 1752|Homo sapiens protein ( Human desmoplak... 59 5e-08
BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,... 59 5e-08
AL031058-1|CAA19927.1| 2871|Homo sapiens desmoplakin protein. 59 5e-08
AY610514-1|AAT37906.1| 1302|Homo sapiens paracingulin protein. 58 8e-08
BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,... 58 1e-07
BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,... 58 1e-07
AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin he... 58 1e-07
AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin he... 58 1e-07
AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY... 58 1e-07
AB053468-1|BAC54107.1| 992|Homo sapiens ELKS beta protein. 58 1e-07
AB029004-1|BAA83033.2| 1003|Homo sapiens KIAA1081 protein protein. 58 1e-07
AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein. 58 1e-07
AB015617-1|BAA88763.1| 948|Homo sapiens ELKS protein. 58 1e-07
BC126409-1|AAI26410.1| 1941|Homo sapiens myosin, heavy chain 2, ... 57 2e-07
AF111784-1|AAD29950.1| 1941|Homo sapiens myosin heavy chain IIa ... 57 2e-07
AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion prote... 56 3e-07
AJ131693-1|CAB40713.1| 3908|Homo sapiens AKAP450 protein protein. 56 3e-07
AJ010770-1|CAA09361.1| 3911|Homo sapiens Hyperion protein protein. 56 3e-07
AF026245-1|AAB86384.1| 1642|Homo sapiens yotiao protein. 56 3e-07
AC000066-1|AAC60380.1| 1620|Homo sapiens yotiao protein. 56 3e-07
AB019691-1|BAA78718.1| 3899|Homo sapiens Centrosome- and Golgi-l... 56 3e-07
D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heav... 56 4e-07
AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein. 56 4e-07
AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting cit... 56 4e-07
AC002563-2|AAB71327.1| 1286|Homo sapiens WUGSC:H_127H14.1 protein. 56 4e-07
AB023166-1|BAA76793.2| 1559|Homo sapiens KIAA0949 protein protein. 56 4e-07
AL139421-3|CAI22510.1| 1044|Homo sapiens coiled-coil domain cont... 56 6e-07
AF083037-1|AAD22767.1| 3595|Homo sapiens A-kinase anchoring prot... 56 6e-07
X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein. 55 1e-06
D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372 prot... 55 1e-06
BC127816-1|AAI27817.1| 416|Homo sapiens Unknown (protein for IM... 55 1e-06
AB053469-1|BAC54108.1| 720|Homo sapiens ELKS gamma protein. 55 1e-06
AL139421-1|CAI22508.1| 1454|Homo sapiens coiled-coil domain cont... 54 1e-06
U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-co... 54 2e-06
AF273047-1|AAG34907.1| 623|Homo sapiens CTCL tumor antigen se20... 54 2e-06
Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein. 54 2e-06
M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle... 54 2e-06
BC128578-1|AAI28579.1| 751|Homo sapiens RRBP1 protein protein. 54 2e-06
AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain prot... 54 2e-06
AF006751-1|AAC25977.1| 977|Homo sapiens ES/130 protein. 54 2e-06
U19769-1|AAA82889.1| 3210|Homo sapiens CENP-F kinetochore protei... 53 3e-06
BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated, coiled-... 53 3e-06
AL445666-1|CAH71810.1| 3114|Homo sapiens centromere protein F, 3... 53 3e-06
AL445305-6|CAH73032.1| 3114|Homo sapiens centromere protein F, 3... 53 3e-06
X95654-1|CAA64956.1| 976|Homo sapiens polypeptide of 976 aa pro... 53 4e-06
BC126266-1|AAI26267.1| 976|Homo sapiens synaptonemal complex pr... 53 4e-06
AY282407-1|AAP40331.1| 1116|Homo sapiens M-phase phosphoprotein ... 53 4e-06
AL645502-1|CAH70064.1| 976|Homo sapiens synaptonemal complex pr... 53 4e-06
AL358372-3|CAH72848.1| 792|Homo sapiens synaptonemal complex pr... 53 4e-06
AL358372-2|CAH72847.1| 976|Homo sapiens synaptonemal complex pr... 53 4e-06
AF273043-1|AAG34903.1| 795|Homo sapiens CTCL tumor antigen se2-... 53 4e-06
AB033337-1|BAB69456.1| 1820|Homo sapiens mitotic kinesin-related... 53 4e-06
U93121-1|AAB88727.1| 753|Homo sapiens M-phase phosphoprotein-1 ... 52 5e-06
AY739715-1|AAW65984.1| 617|Homo sapiens M-phase phosphoprotein ... 52 5e-06
AK126045-1|BAC86410.1| 978|Homo sapiens galactosaminyltransfera... 52 5e-06
AK024959-1|BAB15043.1| 696|Homo sapiens protein ( Homo sapiens ... 52 5e-06
D67035-1|BAA22586.1| 973|Homo sapiens SCP-1 protein. 52 7e-06
AL132765-6|CAC10587.1| 977|Homo sapiens ribosome binding protei... 52 7e-06
AL132765-4|CAH74034.1| 1410|Homo sapiens ribosome binding protei... 52 7e-06
BC027860-1|AAH27860.1| 893|Homo sapiens filamin A interacting p... 52 9e-06
AY642382-1|AAV34207.1| 1135|Homo sapiens GPBP-interacting protei... 52 9e-06
AF514869-1|AAQ08179.1| 1133|Homo sapiens GPBP-interacting protei... 52 9e-06
AF514868-1|AAQ08178.1| 1133|Homo sapiens GPBP-interacting protei... 52 9e-06
AF514867-1|AAQ08177.1| 1135|Homo sapiens GPBP-interacting protei... 52 9e-06
AF329092-1|AAN16206.1| 764|Homo sapiens GPBP-interacting protei... 52 9e-06
BC128577-1|AAI28578.1| 934|Homo sapiens RRBP1 protein protein. 51 1e-05
BC000099-1|AAH00099.4| 655|Homo sapiens RRBP1 protein protein. 51 1e-05
AL157400-6|CAI16830.1| 1820|Homo sapiens M-phase phosphoprotein ... 51 1e-05
AL157400-5|CAI16831.1| 1780|Homo sapiens M-phase phosphoprotein ... 51 1e-05
AL157389-3|CAI12887.1| 1780|Homo sapiens M-phase phosphoprotein ... 51 1e-05
AL157389-2|CAI12886.1| 1820|Homo sapiens M-phase phosphoprotein ... 51 1e-05
AL137068-7|CAD20123.1| 1007|Homo sapiens centrosomal protein 110... 51 1e-05
AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein. 51 1e-05
AB037819-1|BAA92636.2| 1586|Homo sapiens KIAA1398 protein protein. 51 1e-05
M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy ch... 51 2e-05
AY237537-1|AAP04414.1| 1335|Homo sapiens KIF27B protein. 51 2e-05
Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9, no... 50 2e-05
CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein. 50 2e-05
BC031046-1|AAH31046.1| 495|Homo sapiens meiosis-specific nuclea... 50 2e-05
AF382188-1|AAK60542.1| 484|Homo sapiens NYD-SP28 protein. 50 2e-05
AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy... 50 2e-05
Y12490-1|CAA73095.1| 1979|Homo sapiens Golgi-associated microtub... 50 3e-05
X66397-1|CAA47021.1| 2349|Homo sapiens Tpr protein. 50 3e-05
U69668-1|AAB48030.1| 2363|Homo sapiens Tpr protein. 50 3e-05
D86970-1|BAA13206.2| 2067|Homo sapiens KIAA0216 protein. 50 3e-05
BX641024-1|CAE46015.1| 1694|Homo sapiens hypothetical protein pr... 50 3e-05
BC132736-1|AAI32737.1| 1843|Homo sapiens KIAA1212 protein. 50 3e-05
BC034991-1|AAH34991.1| 495|Homo sapiens meiosis-specific nuclea... 50 3e-05
AY703984-1|AAV80770.1| 1581|Homo sapiens SP-A receptor subunit S... 50 3e-05
AY651261-1|AAX35689.1| 1244|Homo sapiens centrosomal protein 1 p... 50 3e-05
AL596220-1|CAI13119.1| 2363|Homo sapiens translocated promoter r... 50 3e-05
AL137068-6|CAI12359.1| 346|Homo sapiens centrosomal protein 110... 50 3e-05
AL137068-5|CAI12358.1| 1773|Homo sapiens centrosomal protein 110... 50 3e-05
AL137068-2|CAM13285.1| 2325|Homo sapiens centrosomal protein 110... 50 3e-05
AL133553-3|CAI17859.1| 2363|Homo sapiens translocated promoter r... 50 3e-05
AK074079-1|BAB84905.1| 1793|Homo sapiens FLJ00150 protein protein. 50 3e-05
AK002084-1|BAA92077.1| 495|Homo sapiens protein ( Homo sapiens ... 50 3e-05
AF513978-1|AAP43846.1| 2325|Homo sapiens CENTRIOLIN protein. 50 3e-05
AF083322-1|AAC32373.1| 994|Homo sapiens centriole associated pr... 50 3e-05
AF007217-1|AAD09135.1| 1978|Homo sapiens Trip230 protein. 50 3e-05
AC012487-1|AAX88838.1| 1583|Homo sapiens unknown protein. 50 3e-05
AB177860-1|BAD66838.1| 1715|Homo sapiens KIAA0216 splice variant... 50 3e-05
AB177858-1|BAD66836.1| 2046|Homo sapiens KIAA0216 splice variant... 50 3e-05
AB125644-1|BAF44475.1| 1843|Homo sapiens PKB/Akt-binding protein... 50 3e-05
X03740-1|CAA27380.1| 876|Homo sapiens protein ( Human skeletal ... 50 4e-05
U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein. 50 4e-05
X69292-1|CAA49154.1| 881|Homo sapiens smooth muscle mysosin he... 49 5e-05
BC114545-1|AAI14546.1| 1939|Homo sapiens myosin, heavy chain 1, ... 49 5e-05
AL627308-5|CAH71336.1| 1732|Homo sapiens CDC42 binding protein k... 49 5e-05
AL627308-3|CAH71337.1| 1719|Homo sapiens CDC42 binding protein k... 49 5e-05
AL451047-3|CAH71185.1| 1732|Homo sapiens CDC42 binding protein k... 49 5e-05
AL451047-1|CAH71183.1| 1719|Homo sapiens CDC42 binding protein k... 49 5e-05
AL353689-9|CAI19109.1| 1732|Homo sapiens CDC42 binding protein k... 49 5e-05
AL353689-7|CAI19108.1| 1719|Homo sapiens CDC42 binding protein k... 49 5e-05
AK097517-1|BAC05084.1| 621|Homo sapiens protein ( Homo sapiens ... 49 5e-05
AJ518975-1|CAD57745.1| 1719|Homo sapiens CDC42 binding protein k... 49 5e-05
AF111785-1|AAD29951.1| 1939|Homo sapiens myosin heavy chain IIx/... 49 5e-05
AB208968-1|BAD92205.1| 1702|Homo sapiens CDC42 binding protein k... 49 5e-05
X52889-1|CAA37068.1| 1934|Homo sapiens cardiac beta myosin heavy... 49 7e-05
X51591-1|CAA35940.1| 1151|Homo sapiens beta-myosin heavy chain (... 49 7e-05
AB059622-1|BAB69690.1| 1594|Homo sapiens Rb1-inducible coiled co... 49 7e-05
BC101026-1|AAI01027.1| 490|Homo sapiens SASS6 protein protein. 48 9e-05
BC056146-1|AAH56146.1| 718|Homo sapiens hook homolog 3 (Drosoph... 48 9e-05
BC039317-1|AAH39317.2| 484|Homo sapiens coiled-coil domain cont... 48 9e-05
AK093051-1|BAC04035.1| 484|Homo sapiens protein ( Homo sapiens ... 48 9e-05
AF241830-1|AAK29204.1| 718|Homo sapiens golgi-associated microt... 48 9e-05
Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heav... 48 1e-04
M81105-1|AAA59888.1| 1337|Homo sapiens cellular myosin heavy cha... 48 1e-04
BC049849-1|AAH49849.1| 1374|Homo sapiens Unknown (protein for IM... 48 1e-04
BC028423-1|AAH28423.1| 1022|Homo sapiens PMFBP1 protein protein. 48 1e-04
AY368076-1|AAR04774.1| 1674|Homo sapiens kinesin family member 2... 48 1e-04
AK098529-1|BAC05324.1| 302|Homo sapiens protein ( Homo sapiens ... 48 1e-04
AK027863-1|BAB55415.1| 612|Homo sapiens protein ( Homo sapiens ... 48 1e-04
X51592-1|CAA35941.1| 1437|Homo sapiens fetal-myosin heavy chain ... 48 2e-04
M58018-1|AAA62830.1| 1935|Homo sapiens beta-myosin heavy chain p... 48 2e-04
M57965-1|AAA51837.1| 1935|Homo sapiens beta-myosin heavy chain p... 48 2e-04
EF179180-1|ABN05283.1| 1935|Homo sapiens myosin, heavy chain 7, ... 48 2e-04
D86958-1|BAA13194.2| 1593|Homo sapiens KIAA0203 protein. 48 2e-04
D00943-1|BAA00791.1| 1939|Homo sapiens cardiac alpha-myosin heav... 48 2e-04
BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6, ... 48 2e-04
BC130453-1|AAI30454.1| 1726|Homo sapiens ANKRD26 protein protein. 48 2e-04
BC117174-1|AAI17175.1| 1291|Homo sapiens KIF15 protein protein. 48 2e-04
BC112173-1|AAI12174.1| 1935|Homo sapiens myosin, heavy chain 7, ... 48 2e-04
BC112171-1|AAI12172.1| 1935|Homo sapiens myosin, heavy chain 7, ... 48 2e-04
BC017556-1|AAH17556.1| 1594|Homo sapiens RB1-inducible coiled-co... 48 2e-04
AY518538-1|AAT44534.1| 1179|Homo sapiens rhabdomyosarcoma antige... 48 2e-04
AL162272-4|CAC19649.1| 1710|Homo sapiens novel protein protein. 48 2e-04
AL139421-4|CAI22511.1| 720|Homo sapiens coiled-coil domain cont... 48 2e-04
AK128577-1|BAC87508.1| 1080|Homo sapiens protein ( Homo sapiens ... 48 2e-04
AK093463-1|BAC04173.1| 650|Homo sapiens protein ( Homo sapiens ... 48 2e-04
AK056673-1|BAB71249.1| 883|Homo sapiens protein ( Homo sapiens ... 48 2e-04
AJ238393-1|CAC20413.1| 1935|Homo sapiens beta-myosin heavy chain... 48 2e-04
AF111783-1|AAD29949.1| 1939|Homo sapiens myosin heavy chain IIb ... 48 2e-04
AB209708-1|BAD92945.1| 1574|Homo sapiens myosin, heavy polypepti... 48 2e-04
AB035898-1|BAB03309.1| 1388|Homo sapiens kinesin-like protein 2 ... 48 2e-04
AB028997-1|BAA83026.2| 1715|Homo sapiens KIAA1074 protein protein. 48 2e-04
X64838-1|CAA46050.1| 1427|Homo sapiens restin protein. 47 2e-04
U53445-1|AAA98972.1| 752|Homo sapiens DOC1 protein. 47 2e-04
M97501-1|AAA35693.1| 1392|Homo sapiens cytoplasmic linker protei... 47 2e-04
BX537964-1|CAD97928.1| 898|Homo sapiens hypothetical protein pr... 47 2e-04
BC126305-1|AAI26306.1| 1438|Homo sapiens CLIP1 protein protein. 47 2e-04
BC105632-1|AAI05633.1| 898|Homo sapiens chromosome 10 open read... 47 2e-04
BC103499-1|AAI03500.1| 898|Homo sapiens chromosome 10 open read... 47 2e-04
BC100670-1|AAI00671.1| 1004|Homo sapiens C10orf118 protein protein. 47 2e-04
AF450487-1|AAP97680.1| 1662|Homo sapiens kinesin-like protein KI... 47 2e-04
AF273054-1|AAM44457.1| 613|Homo sapiens CTCL tumor antigen HD-C... 47 2e-04
DQ109808-1|AAZ83370.1| 2479|Homo sapiens nephrocystin-6 protein. 47 3e-04
BX284668-3|CAH70057.1| 1898|Homo sapiens ciliary rootlet coiled-... 47 3e-04
BX284668-2|CAH70055.1| 2017|Homo sapiens ciliary rootlet coiled-... 47 3e-04
BC126912-1|AAI26913.1| 1132|Homo sapiens CROCC protein protein. 47 3e-04
BC126911-1|AAI26912.1| 1132|Homo sapiens CROCC protein protein. 47 3e-04
BC117209-1|AAI17210.1| 1438|Homo sapiens CLIP1 protein protein. 47 3e-04
AL832639-1|CAD89954.1| 1331|Homo sapiens hypothetical protein pr... 47 3e-04
AL049569-4|CAI20365.1| 1898|Homo sapiens ciliary rootlet coiled-... 47 3e-04
AL049569-3|CAI20363.1| 2017|Homo sapiens ciliary rootlet coiled-... 47 3e-04
AF273044-1|AAG34904.1| 761|Homo sapiens CTCL tumor antigen se2-... 47 3e-04
AB007914-1|BAA32290.2| 1919|Homo sapiens KIAA0445 protein protein. 47 3e-04
AB002371-1|BAA20828.2| 1540|Homo sapiens KIAA0373 protein. 47 3e-04
BX538286-1|CAD98081.1| 724|Homo sapiens hypothetical protein pr... 46 3e-04
BC051733-1|AAH51733.1| 1026|Homo sapiens LUZP1 protein protein. 46 3e-04
AL031428-1|CAI19705.1| 1026|Homo sapiens leucine zipper protein ... 46 3e-04
AK074153-1|BAB84979.1| 1046|Homo sapiens FLJ00226 protein protein. 46 3e-04
AK023707-1|BAB14650.1| 435|Homo sapiens protein ( Homo sapiens ... 46 3e-04
AB231311-1|BAE78964.1| 390|Homo sapiens Nucb2 splice variant pr... 46 3e-04
AB208965-1|BAD92202.1| 705|Homo sapiens Rho-associated, coiled-... 46 3e-04
BC080545-1|AAH80545.1| 498|Homo sapiens MYH11 protein protein. 46 5e-04
AM177179-1|CAJ45483.1| 1621|Homo sapiens kinesin-like protein KI... 46 5e-04
AK021596-1|BAB13850.1| 619|Homo sapiens protein ( Homo sapiens ... 46 5e-04
AB051495-1|BAB21799.2| 1657|Homo sapiens KIAA1708 protein. 46 5e-04
BC057235-1|AAH57235.1| 613|Homo sapiens HMMR protein protein. 46 6e-04
BC011615-1|AAH11615.2| 739|Homo sapiens AZI1 protein protein. 46 6e-04
BC006984-1|AAH06984.1| 512|Homo sapiens Unknown (protein for IM... 46 6e-04
AY237536-1|AAP04413.1| 1401|Homo sapiens KIF27A protein. 46 6e-04
AL354733-4|CAI16013.1| 1401|Homo sapiens kinesin family member 2... 46 6e-04
AL133654-1|CAB63770.1| 833|Homo sapiens hypothetical protein pr... 46 6e-04
AB029041-1|BAA83070.1| 1165|Homo sapiens KIAA1118 protein protein. 46 6e-04
Z11584-1|CAA77670.1| 2101|Homo sapiens NuMA protein protein. 45 8e-04
Z11583-1|CAA77669.1| 2115|Homo sapiens NuMA protein protein. 45 8e-04
U33822-1|AAC52059.1| 803|Homo sapiens TXBP181 protein. 45 8e-04
BC113409-1|AAI13410.1| 1416|Homo sapiens uveal autoantigen with ... 45 8e-04
BC113407-1|AAI13408.1| 1416|Homo sapiens uveal autoantigen with ... 45 8e-04
BC103765-1|AAI03766.1| 691|Homo sapiens NUMA1 protein protein. 45 8e-04
BC027493-1|AAH27493.1| 691|Homo sapiens Unknown (protein for IM... 45 8e-04
AF322916-1|AAG49577.1| 1416|Homo sapiens uveal autoantigen protein. 45 8e-04
AB210007-1|BAE06089.1| 2121|Homo sapiens NUMA1 variant protein p... 45 8e-04
AB046781-1|BAB13387.2| 1416|Homo sapiens KIAA1561 protein protein. 45 8e-04
BC117132-1|AAI17133.1| 1306|Homo sapiens kinectin 1 (kinesin rec... 45 0.001
BC114213-1|AAI14214.1| 1392|Homo sapiens CAP-GLY domain containi... 45 0.001
BC112337-1|AAI12338.1| 1306|Homo sapiens kinectin 1 (kinesin rec... 45 0.001
AL360170-2|CAH70404.1| 1235|Homo sapiens Ste20-related serine\/t... 45 0.001
AL138761-2|CAI12395.1| 1235|Homo sapiens Ste20-related serine\/t... 45 0.001
AK090540-1|BAC03473.1| 373|Homo sapiens protein ( Homo sapiens ... 45 0.001
AF273048-1|AAG34908.1| 1235|Homo sapiens CTCL tumor antigen se20... 45 0.001
Z75311-1|CAA99729.1| 1318|Homo sapiens RAD50 homologue hsRAD50 p... 44 0.001
X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for ... 44 0.001
X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 ... 44 0.001
BC047324-1|AAH47324.1| 1217|Homo sapiens structural maintenance ... 44 0.001
BC043398-1|AAH43398.1| 805|Homo sapiens CEP290 protein protein. 44 0.001
AY517555-1|AAT44528.1| 941|Homo sapiens hypothetical rhabdomyos... 44 0.001
AL359260-2|CAI16576.1| 1217|Homo sapiens structural maintenance ... 44 0.001
AK055217-1|BAB70876.1| 688|Homo sapiens protein ( Homo sapiens ... 44 0.001
AK023677-1|BAB14636.1| 574|Homo sapiens protein ( Homo sapiens ... 44 0.001
AF317887-1|AAK01919.1| 589|Homo sapiens monoclonal antibody 3H1... 44 0.001
AF020043-1|AAC14893.1| 1217|Homo sapiens chromosome-associated p... 44 0.001
AB111886-1|BAC98374.1| 1571|Homo sapiens KIAA2034 protein protein. 44 0.001
U90028-1|AAB94805.1| 975|Homo sapiens bicaudal-D protein. 44 0.002
AK092201-1|BAC03827.1| 284|Homo sapiens protein ( Homo sapiens ... 44 0.002
AB209115-1|BAD92352.1| 1065|Homo sapiens restin isoform a varian... 44 0.002
AB023217-1|BAA76844.2| 1956|Homo sapiens KIAA1000 protein protein. 44 0.002
Z22551-1|CAA80271.1| 1356|Homo sapiens 156 kDa Protein protein. 44 0.002
X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy ch... 44 0.002
X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mR... 44 0.002
U29343-1|AAC52049.1| 725|Homo sapiens hyaluronan receptor protein. 44 0.002
D64159-1|BAA21515.1| 709|Homo sapiens 3-7 gene product protein. 44 0.002
BX537985-1|CAD97945.1| 1202|Homo sapiens hypothetical protein pr... 44 0.002
BC108904-1|AAI08905.1| 725|Homo sapiens hyaluronan-mediated mot... 44 0.002
BC078168-1|AAH78168.1| 887|Homo sapiens KIAA1212 protein protein. 44 0.002
BC057227-1|AAH57227.1| 318|Homo sapiens Unknown (protein for IM... 44 0.002
BC021171-1|AAH21171.2| 320|Homo sapiens NUF2 protein protein. 44 0.002
BC008489-1|AAH08489.1| 464|Homo sapiens NUF2, NDC80 kinetochore... 44 0.002
AL592435-3|CAI16706.1| 464|Homo sapiens cell division cycle ass... 44 0.002
AK093348-1|BAC04140.1| 464|Homo sapiens protein ( Homo sapiens ... 44 0.002
AK022365-1|BAB14022.1| 534|Homo sapiens protein ( Homo sapiens ... 44 0.002
AF326731-1|AAK01426.1| 464|Homo sapiens NUF2R protein. 44 0.002
AF112218-1|AAF17206.1| 742|Homo sapiens unknown protein. 44 0.002
AF032862-1|AAC32548.1| 724|Homo sapiens intracellular hyaluroni... 44 0.002
AB058704-1|BAB47430.1| 1227|Homo sapiens KIAA1801 protein protein. 44 0.002
AB050578-1|BAB59142.1| 303|Homo sapiens kinetochore protein Nuf... 44 0.002
AB050577-1|BAB59141.1| 464|Homo sapiens kinetochore protein Nuf... 44 0.002
U63139-1|AAB07119.1| 1312|Homo sapiens Rad50 protein. 43 0.003
L12579-1|AAA35654.1| 678|Homo sapiens protein ( Human alternati... 43 0.003
BC109126-1|AAI09127.1| 872|Homo sapiens chromosome 10 open read... 43 0.003
BC066592-1|AAH66592.1| 1516|Homo sapiens CUTL1 protein protein. 43 0.003
BC036225-1|AAH36225.1| 872|Homo sapiens chromosome 10 open read... 43 0.003
BC025422-1|AAH25422.1| 676|Homo sapiens cut-like 1, CCAAT displ... 43 0.003
AL355378-1|CAI15667.1| 872|Homo sapiens novel protein protein. 43 0.003
AL162742-5|CAI12110.1| 872|Homo sapiens novel protein protein. 43 0.003
AL121586-4|CAB89415.1| 2442|Homo sapiens centrosomal protein 250... 43 0.003
AK222832-1|BAD96552.1| 678|Homo sapiens CCAAT displacement prot... 43 0.003
AK093227-1|BAC04102.1| 550|Homo sapiens protein ( Homo sapiens ... 43 0.003
AF057300-1|AAD50326.1| 1173|Homo sapiens truncated RAD50 protein... 43 0.003
AF057299-1|AAD50325.1| 1312|Homo sapiens RAD50-2 protein protein. 43 0.003
AF049105-1|AAC07988.1| 2442|Homo sapiens centrosomal Nek2-associ... 43 0.003
AC005086-1|AAP22331.1| 317|Homo sapiens unknown protein. 43 0.003
D86959-1|BAA13195.2| 1164|Homo sapiens KIAA0204 protein protein. 43 0.004
BC111565-1|AAI11566.1| 1204|Homo sapiens SLK protein protein. 43 0.004
BC108282-1|AAI08283.1| 723|Homo sapiens Unknown (protein for IM... 43 0.004
BC073850-1|AAH73850.1| 723|Homo sapiens RAD50 protein protein. 43 0.004
BC070281-1|AAH70281.1| 552|Homo sapiens HMMR protein protein. 43 0.004
BC039612-1|AAH39612.1| 2002|Homo sapiens MYO18A protein protein. 43 0.004
AY528715-1|AAT44400.1| 1016|Homo sapiens antigen MU-RMS-40.16A p... 43 0.004
AL360170-1|CAH70403.1| 1204|Homo sapiens Ste20-related serine\/t... 43 0.004
AL138761-1|CAI12396.1| 1204|Homo sapiens Ste20-related serine\/t... 43 0.004
AF155115-1|AAD42881.1| 472|Homo sapiens NY-REN-58 antigen protein. 43 0.004
AF091711-1|AAD39719.1| 1773|Homo sapiens splice variant AKAP350 ... 43 0.004
AC004013-1|AAB96867.2| 2058|Homo sapiens unknown protein. 43 0.004
AB002804-1|BAA19655.1| 1204|Homo sapiens hSLK protein. 43 0.004
U52962-1|AAD10838.1| 3321|Homo sapiens kendrin protein. 42 0.006
BC129821-1|AAI29822.1| 315|Homo sapiens FLJ36144 protein protein. 42 0.006
BC125087-1|AAI25088.1| 568|Homo sapiens CCDC41 protein protein. 42 0.006
BC125086-1|AAI25087.1| 634|Homo sapiens CCDC41 protein protein. 42 0.006
AF515282-1|AAP46636.1| 3336|Homo sapiens pericentrin B protein. 42 0.006
AB023222-1|BAA76849.1| 1055|Homo sapiens KIAA1005 protein protein. 42 0.006
U25725-1|AAA86889.1| 1017|Homo sapiens AH antigen protein. 42 0.007
U22816-1|AAC50173.1| 1202|Homo sapiens LAR-interacting protein 1... 42 0.007
U22815-1|AAC50172.1| 1185|Homo sapiens LAR-interacting protein 1... 42 0.007
BC050434-1|AAH50434.1| 273|Homo sapiens FLJ10154 protein protein. 42 0.007
BC034046-1|AAH34046.1| 1202|Homo sapiens protein tyrosine phosph... 42 0.007
AY884293-1|AAX84184.1| 1117|Homo sapiens cytospin A protein. 42 0.007
AL590377-2|CAI14630.2| 1406|Homo sapiens chromosome 9 open readi... 42 0.007
AL442127-3|CAI13168.1| 273|Homo sapiens RP11-297I6.1 protein. 42 0.007
AL354738-1|CAI16195.2| 1406|Homo sapiens chromosome 9 open readi... 42 0.007
AL354711-1|CAH72682.2| 1406|Homo sapiens chromosome 9 open readi... 42 0.007
AL162725-3|CAH70424.1| 1406|Homo sapiens chromosome 9 open readi... 42 0.007
AL133214-3|CAH70743.2| 1406|Homo sapiens chromosome 9 open readi... 42 0.007
AK001016-1|BAA91467.1| 273|Homo sapiens protein ( Homo sapiens ... 42 0.007
AB209022-1|BAD92259.1| 939|Homo sapiens KIAA0376 protein varian... 42 0.007
AB002374-1|BAA21574.1| 885|Homo sapiens KIAA0376 protein. 42 0.007
BC009964-1|AAH09964.1| 718|Homo sapiens MAD1 mitotic arrest def... 42 0.010
AL591543-1|CAI17285.1| 992|Homo sapiens ankyrin repeat domain 1... 42 0.010
AF123318-1|AAD20359.1| 718|Homo sapiens mitotic checkpoint prot... 42 0.010
X06976-1|CAA30039.1| 543|Homo sapiens beta myosin heavy chain (... 41 0.013
U78311-1|AAB80695.1| 1382|Homo sapiens translation initiation fa... 41 0.013
U58046-1|AAB41584.1| 1382|Homo sapiens p167 protein. 41 0.013
M25139-1|AAA60385.1| 611|Homo sapiens myosin heavy chain beta-s... 41 0.013
M17712-1|AAA36343.1| 543|Homo sapiens protein ( Human cardiac m... 41 0.013
D50929-1|BAA09488.2| 1388|Homo sapiens KIAA0139 protein. 41 0.013
BX537855-1|CAD97863.1| 974|Homo sapiens hypothetical protein pr... 41 0.013
BC114429-1|AAI14430.1| 1382|Homo sapiens eukaryotic translation ... 41 0.013
BC062603-1|AAH62603.1| 557|Homo sapiens Unknown (protein for IM... 41 0.013
BC017793-1|AAH17793.1| 331|Homo sapiens Unknown (protein for IM... 41 0.013
BC002932-1|AAH02932.1| 850|Homo sapiens CEP110 protein protein. 41 0.013
AL355598-2|CAI14127.1| 1382|Homo sapiens eukaryotic translation ... 41 0.013
AL137068-4|CAI12357.1| 994|Homo sapiens centrosomal protein 110... 41 0.013
AF022655-1|AAC06349.1| 2442|Homo sapiens cep250 centrosome assoc... 41 0.013
Z98946-1|CAB46379.1| 577|Homo sapiens moesin protein. 41 0.017
Z29064-1|CAA82305.1| 896|Homo sapiens AF-1p protein. 41 0.017
U07707-1|AAA52101.1| 896|Homo sapiens epidermal growth factor r... 41 0.017
M69066-1|AAA36322.1| 577|Homo sapiens moesin B protein. 41 0.017
DQ367924-1|ABD34786.1| 896|Homo sapiens epidermal growth factor... 41 0.017
BC045542-1|AAH45542.1| 702|Homo sapiens KIF3A protein protein. 41 0.017
BC017293-1|AAH17293.1| 577|Homo sapiens moesin protein. 41 0.017
AL671986-11|CAI13030.1| 896|Homo sapiens epidermal growth facto... 41 0.017
AL139421-2|CAI22509.1| 228|Homo sapiens coiled-coil domain cont... 41 0.017
AK131384-1|BAD18535.1| 326|Homo sapiens protein ( Homo sapiens ... 41 0.017
AK000283-1|BAA91052.1| 1084|Homo sapiens protein ( Homo sapiens ... 41 0.017
AF295356-1|AAK71522.1| 527|Homo sapiens moesin/anaplastic lymph... 41 0.017
AF083811-1|AAD24498.1| 718|Homo sapiens mitotic checkpoint prot... 41 0.017
AB209780-1|BAD93017.1| 730|Homo sapiens Kinesin-like protein KI... 41 0.017
AB208841-1|BAD92078.1| 1585|Homo sapiens Nuclear mitotic apparat... 41 0.017
AB018346-1|BAA34523.1| 1708|Homo sapiens KIAA0803 protein protein. 41 0.017
X05276-1|CAA28888.1| 248|Homo sapiens protein ( Human mRNA for ... 40 0.023
U28963-1|AAB60432.1| 327|Homo sapiens Gps2 protein. 40 0.023
M21665-1|AAA36345.1| 524|Homo sapiens protein ( Human beta-myos... 40 0.023
M21664-1|AAA36344.1| 532|Homo sapiens protein ( Human alpha-myo... 40 0.023
DQ120629-1|ABB92415.1| 1185|Homo sapiens KIF4B protein. 40 0.023
CR541750-1|CAG46550.1| 327|Homo sapiens GPS2 protein. 40 0.023
CR541723-1|CAG46524.1| 327|Homo sapiens GPS2 protein. 40 0.023
BX537708-1|CAD97819.1| 1605|Homo sapiens hypothetical protein pr... 40 0.023
BX537421-1|CAD97663.1| 1204|Homo sapiens hypothetical protein pr... 40 0.023
BT019634-1|AAV38440.1| 248|Homo sapiens tropomyosin 4 protein. 40 0.023
BT006998-1|AAP35644.1| 327|Homo sapiens G protein pathway suppr... 40 0.023
BC107738-1|AAI07739.1| 327|Homo sapiens G protein pathway suppr... 40 0.023
BC104912-1|AAI04913.1| 1236|Homo sapiens PPFIA2 protein protein. 40 0.023
BC103903-1|AAI03904.1| 327|Homo sapiens G protein pathway suppr... 40 0.023
BC103901-1|AAI03902.1| 327|Homo sapiens G protein pathway suppr... 40 0.023
BC067225-1|AAH67225.1| 248|Homo sapiens tropomyosin 4 protein. 40 0.023
BC037576-1|AAH37576.1| 248|Homo sapiens tropomyosin 4 protein. 40 0.023
BC013652-1|AAH13652.1| 327|Homo sapiens G protein pathway suppr... 40 0.023
AY639646-1|AAX19141.1| 572|Homo sapiens prefoldin subunit 6-lik... 40 0.023
AY536375-1|AAT66048.1| 820|Homo sapiens rhabdomyosarcoma antige... 40 0.023
AY264265-1|AAP20418.1| 1357|Homo sapiens kinectin variant 1 prot... 40 0.023
AL590642-2|CAH70770.1| 862|Homo sapiens CDK5 regulatory subunit... 40 0.023
AL590642-1|CAH70769.1| 1893|Homo sapiens CDK5 regulatory subunit... 40 0.023
AL445669-8|CAH70752.1| 783|Homo sapiens novel protein protein. 40 0.023
AL391870-2|CAI40925.1| 1893|Homo sapiens CDK5 regulatory subunit... 40 0.023
AL391870-1|CAI40926.1| 862|Homo sapiens CDK5 regulatory subunit... 40 0.023
AL353736-2|CAI40654.1| 862|Homo sapiens CDK5 regulatory subunit... 40 0.023
AL353736-1|CAI40653.1| 1893|Homo sapiens CDK5 regulatory subunit... 40 0.023
AL138836-2|CAI16963.1| 1893|Homo sapiens CDK5 regulatory subunit... 40 0.023
AL138836-1|CAI16964.1| 862|Homo sapiens CDK5 regulatory subunit... 40 0.023
AL138788-1|CAI22439.1| 783|Homo sapiens novel protein protein. 40 0.023
AL122080-1|CAB59255.1| 327|Homo sapiens hypothetical protein pr... 40 0.023
AK025336-1|BAB15114.1| 963|Homo sapiens protein ( Homo sapiens ... 40 0.023
AJ292348-1|CAC33883.1| 1478|Homo sapiens FYVE and coiled-coil do... 40 0.023
AF448860-1|AAP41926.1| 1893|Homo sapiens hypothetical protein pr... 40 0.023
AB046853-1|BAB13459.2| 1852|Homo sapiens KIAA1633 protein protein. 40 0.023
AB040938-1|BAA96029.1| 693|Homo sapiens KIAA1505 protein protein. 40 0.023
Y17829-1|CAA76877.1| 354|Homo sapiens Syn47 protein protein. 40 0.030
L25616-1|AAB65853.1| 1300|Homo sapiens kinectin protein. 40 0.030
L16782-1|AAC37542.1| 566|Homo sapiens putative M phase phosphop... 40 0.030
D63997-1|BAA23661.1| 1530|Homo sapiens GCP170 protein. 40 0.030
D13629-1|BAA02794.2| 1307|Homo sapiens KIAA0004 protein. 40 0.030
BT009846-1|AAP88848.1| 354|Homo sapiens homer homolog 1 (Drosop... 40 0.030
BC048304-1|AAH48304.1| 597|Homo sapiens HOOK3 protein protein. 40 0.030
BC048203-1|AAH48203.1| 663|Homo sapiens Unknown (protein for IM... 40 0.030
BC015502-1|AAH15502.1| 354|Homo sapiens homer homolog 1 (Drosop... 40 0.030
AY189940-1|AAO39000.1| 180|Homo sapiens HOMER1F protein. 40 0.030
AY189939-1|AAO38999.1| 224|Homo sapiens HOMER1E protein. 40 0.030
AL133324-2|CAI19310.2| 1983|Homo sapiens myosin, heavy chain 7B,... 40 0.030
AL132825-6|CAI43047.2| 1983|Homo sapiens myosin, heavy chain 7B,... 40 0.030
AK097432-1|BAC05050.1| 466|Homo sapiens protein ( Homo sapiens ... 40 0.030
AF485338-1|AAL93149.1| 1498|Homo sapiens golgin-160 protein. 40 0.030
AF293357-1|AAL37035.1| 436|Homo sapiens AT2 receptor-interactin... 40 0.030
AF121259-1|AAG33674.1| 436|Homo sapiens transcription factor MT... 40 0.030
AF093262-1|AAC71026.1| 354|Homo sapiens homer-1b protein. 40 0.030
AB209625-1|BAD92862.1| 459|Homo sapiens dynactin 1 isoform 1 va... 40 0.030
AB040945-1|BAA96036.2| 2010|Homo sapiens KIAA1512 protein protein. 40 0.030
AB033114-1|BAA86602.1| 1245|Homo sapiens KIAA1288 protein protein. 40 0.030
AB027133-1|BAB71953.1| 1390|Homo sapiens male enhanced antigen-2... 40 0.030
X03445-1|CAA27174.1| 572|Homo sapiens protein ( Human mRNA for ... 40 0.040
X03444-1|CAA27173.1| 702|Homo sapiens protein ( Human mRNA for ... 40 0.040
M13451-1|AAA36164.1| 572|Homo sapiens protein ( Human lamin C m... 40 0.040
BX537759-1|CAD97828.1| 1763|Homo sapiens hypothetical protein pr... 40 0.040
BC014507-1|AAH14507.1| 664|Homo sapiens lamin A/C protein. 40 0.040
BC003162-1|AAH03162.1| 572|Homo sapiens lamin A/C protein. 40 0.040
BC000511-1|AAH00511.1| 572|Homo sapiens lamin A/C protein. 40 0.040
AY847597-1|AAW32540.1| 664|Homo sapiens lamin A/C transcript va... 40 0.040
AY847596-1|AAW32539.1| 480|Homo sapiens lamin A/C transcript va... 40 0.040
AY847595-1|AAW32538.1| 664|Homo sapiens lamin A/C transcript va... 40 0.040
AY528714-1|ABB04050.1| 487|Homo sapiens rhabdomyosarcoma antige... 40 0.040
AY358410-1|AAQ88776.1| 296|Homo sapiens SLAP protein. 40 0.040
AY357727-1|AAR29466.1| 614|Homo sapiens progerin protein. 40 0.040
AY166853-1|AAO17292.1| 1317|Homo sapiens kinesin motor protein p... 40 0.040
AL135927-4|CAI15523.1| 614|Homo sapiens lamin A/C protein. 40 0.040
AL135927-3|CAI15522.1| 664|Homo sapiens lamin A/C protein. 40 0.040
AL135927-2|CAI15520.1| 465|Homo sapiens lamin A/C protein. 40 0.040
AL135927-1|CAI15521.1| 572|Homo sapiens lamin A/C protein. 40 0.040
AL118509-3|CAI43063.2| 1392|Homo sapiens chromosome 20 open read... 40 0.040
AL118509-2|CAM28305.1| 1317|Homo sapiens chromosome 20 open read... 40 0.040
AL117376-3|CAI43180.2| 1392|Homo sapiens chromosome 20 open read... 40 0.040
AL117376-2|CAI43181.2| 1317|Homo sapiens chromosome 20 open read... 40 0.040
AL049794-2|CAI22745.2| 1392|Homo sapiens chromosome 20 open read... 40 0.040
AL049794-1|CAM28307.1| 1317|Homo sapiens chromosome 20 open read... 40 0.040
AK128098-1|BAC87273.1| 1185|Homo sapiens protein ( Homo sapiens ... 40 0.040
AK027816-1|BAB55389.1| 436|Homo sapiens protein ( Homo sapiens ... 40 0.040
AK000142-1|BAA90971.1| 752|Homo sapiens protein ( Homo sapiens ... 40 0.040
AB046810-1|BAB13416.2| 1393|Homo sapiens KIAA1590 protein protein. 40 0.040
X98801-1|CAA67333.1| 1263|Homo sapiens dynactin protein. 39 0.053
DQ679757-1|ABG74698.1| 1215|Homo sapiens intersectin 1 short for... 39 0.053
DQ679756-1|ABG74697.1| 1178|Homo sapiens intersectin 1 short for... 39 0.053
DQ679755-1|ABG74696.1| 1149|Homo sapiens intersectin 1 short for... 39 0.053
DQ679754-1|ABG74695.1| 1144|Homo sapiens intersectin 1 short for... 39 0.053
DQ386455-1|ABD72328.1| 1020|Homo sapiens intersectin 1 short for... 39 0.053
DQ340865-1|ABC69037.1| 1076|Homo sapiens intersectin 1 short for... 39 0.053
BX538175-1|CAD98050.1| 627|Homo sapiens hypothetical protein pr... 39 0.053
BC131805-1|AAI31806.1| 913|Homo sapiens CCDC46 protein protein. 39 0.053
BC117560-1|AAI17561.1| 1144|Homo sapiens ITSN1 protein protein. 39 0.053
BC116186-1|AAI16187.1| 1721|Homo sapiens intersectin 1 (SH3 doma... 39 0.053
BC116185-1|AAI16186.1| 1716|Homo sapiens ITSN1 protein protein. 39 0.053
BC115701-1|AAI15702.1| 828|Homo sapiens SLMAP protein protein. 39 0.053
BC071583-1|AAH71583.1| 1139|Homo sapiens DCTN1 protein protein. 39 0.053
BC033088-1|AAH33088.1| 465|Homo sapiens LMNA protein protein. 39 0.053
BC023021-1|AAH23021.1| 731|Homo sapiens golgi autoantigen, golg... 39 0.053
BC002827-1|AAH02827.1| 248|Homo sapiens tropomyosin 4 protein. 39 0.053
AY644768-1|AAV85456.1| 731|Homo sapiens cell proliferation-indu... 39 0.053
AM177178-1|CAJ45482.1| 725|Homo sapiens kinesin-like protein KI... 39 0.053
AK124200-1|BAC85803.1| 506|Homo sapiens protein ( Homo sapiens ... 39 0.053
AK025690-1|BAB15219.1| 746|Homo sapiens protein ( Homo sapiens ... 39 0.053
AF114488-1|AAD29953.1| 1220|Homo sapiens intersectin short isofo... 39 0.053
AF114487-1|AAD29952.1| 1721|Homo sapiens intersectin long isofor... 39 0.053
AF086947-1|AAD03694.1| 1261|Homo sapiens dynactin 1 protein. 39 0.053
AF085199-1|AAD09753.1| 731|Homo sapiens golgin-84 protein. 39 0.053
AF064244-1|AAC78611.1| 1721|Homo sapiens intersectin long form p... 39 0.053
AF064243-1|AAC78610.1| 1220|Homo sapiens intersectin short form ... 39 0.053
AF064205-2|AAD55812.1| 1144|Homo sapiens dynactin 1 p135 isoform... 39 0.053
AF064205-1|AAD55811.1| 1278|Homo sapiens dynactin 1 p150 isoform... 39 0.053
AF041853-1|AAC72294.1| 702|Homo sapiens kinesin family member p... 39 0.053
AB095935-1|BAC23111.1| 996|Homo sapiens KIAA2015 protein protein. 39 0.053
X69910-1|CAA49535.2| 602|Homo sapiens P63 protein protein. 39 0.070
U77845-1|AAB52993.1| 469|Homo sapiens hTRIP protein. 39 0.070
M64110-1|AAA35636.1| 538|Homo sapiens caldesmon protein. 39 0.070
BX119917-1|CAI39851.1| 569|Homo sapiens retrotransposon gag dom... 39 0.070
BC130440-1|AAI30441.1| 1031|Homo sapiens M-phase phosphoprotein ... 39 0.070
BC114627-1|AAI14628.1| 790|Homo sapiens SLMAP protein protein. 39 0.070
BC082972-1|AAH82972.1| 602|Homo sapiens cytoskeleton-associated... 39 0.070
BC067357-1|AAH67357.1| 600|Homo sapiens CKAP4 protein protein. 39 0.070
BC047438-1|AAH47438.1| 354|Homo sapiens homer homolog 1 (Drosop... 39 0.070
BC026101-1|AAH26101.1| 345|Homo sapiens nudE nuclear distributi... 39 0.070
BC025341-1|AAH25341.1| 560|Homo sapiens Similar to cytoskeleton... 39 0.070
BC022873-1|AAH22873.1| 292|Homo sapiens Unknown (protein for IM... 39 0.070
BC019283-1|AAH19283.1| 469|Homo sapiens TRAF interacting protei... 39 0.070
BC000310-1|AAH00310.1| 469|Homo sapiens TRAF interacting protei... 39 0.070
AY004871-1|AAF97497.1| 345|Homo sapiens Nudel protein. 39 0.070
AK223563-1|BAD97283.1| 602|Homo sapiens cytoskeleton-associated... 39 0.070
AK023016-1|BAB14359.1| 692|Homo sapiens protein ( Homo sapiens ... 39 0.070
AF217798-1|AAF24516.3| 345|Homo sapiens endooligopeptidase A pr... 39 0.070
AF182078-1|AAG43425.1| 345|Homo sapiens mitosin-associated prot... 39 0.070
AF034802-1|AAC26103.1| 1005|Homo sapiens liprin-beta1 protein. 39 0.070
AF020091-1|AAB69327.1| 622|Homo sapiens smooth muscle myosin he... 39 0.070
AF013570-1|AAB69326.1| 588|Homo sapiens smooth muscle myosin he... 39 0.070
>AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein
protein.
Length = 2585
Score = 76.6 bits (180), Expect = 3e-13
Identities = 125/654 (19%), Positives = 276/654 (42%), Gaps = 59/654 (9%)
Query: 2 KQEELEIQQNQTDGCLYEDLNEQESITSESHKITKL--KTVWQEKMVTFEKSKKELEDRQ 59
K+++++ Q D E++ S + ES + K +T++ + V + +K+E +
Sbjct: 567 KEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALD-AKRESAFLR 625
Query: 60 NQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHS 119
++ +EL ++ K + + L ++ L ++ E+ LQ A E L S
Sbjct: 626 SENLELKEKMKELATTYKQMENDIQLYQSQ-LEAKKKMQVDLEKELQ-SAFNEITKLT-S 682
Query: 120 TLDNKVTFDV-------NKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKT- 171
+D KV D+ K+ ++ L + EE R+E+I L+S+ K + ++
Sbjct: 683 LIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVI-----LLSELKSLPSEVE 737
Query: 172 -LTMKIKEFNAENDLLKSSLDQLRTEFL-KE--INDIIDCLRKNANETMALQLRTKELSC 227
L +I++ + E ++ S D+L +E + KE + +++ + K ++ Q K
Sbjct: 738 RLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQ 797
Query: 228 ALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLK 287
+ T + + ++ N+ ++ K LS +L+
Sbjct: 798 EFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGAL-KTELSYKTQELQ 856
Query: 288 TNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQ---ELNKLTQSIKDNTT 344
V + +EQ + + + + T+ E Q E+ LTQ D
Sbjct: 857 EKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQ 916
Query: 345 HLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMK-HEMNLN---------IAKLIE 394
E + + R++L+S +++ +K H+ +N +++ +
Sbjct: 917 LQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLH 976
Query: 395 IEKKYNDSIEEKKTLQENID---DLR---TDLLESELRVKDLVRELDEKESILETKQCVQ 448
+E+ ++ +E + ID DL T L ++++ +++ + + S+++ K +Q
Sbjct: 977 MEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQ 1036
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEI----DELKSKLSTEKAIKDIXXXXXXXXX 504
+ LES + E KT+++E + E EE+ DELK + K+
Sbjct: 1037 QMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELS 1096
Query: 505 XXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKL 564
+ Q++ ++L+N++ +++++++ +N++ N+ N+ ++K
Sbjct: 1097 RTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQK-----KINEIENLKNELKNK- 1150
Query: 565 FELTKRQEEYDE-KLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHM 617
ELT E + +L K NE V+S+T++ VL KE++ E E +H+
Sbjct: 1151 -ELTLEHMETERLELAQKLNENYEEVKSITKERKVL----KELQKSFETERDHL 1199
Score = 54.4 bits (125), Expect = 1e-06
Identities = 83/510 (16%), Positives = 204/510 (40%), Gaps = 35/510 (6%)
Query: 147 LFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQL---RTEF-LKEIN 202
L +++E IN +S+++ T+ T++ K+ A ND L++ + ++ +F +K+I+
Sbjct: 1466 LKEQEETINELRVNLSEKE---TEISTIQ-KQLEAINDKLQNKIQEIYEKEEQFNIKQIS 1521
Query: 203 DIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXX 262
++ ++ NE + K AL + ++ E+ ++ +
Sbjct: 1522 EV----QEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKR 1577
Query: 263 XXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQL--EAALEQARSESWSLERTVXXXXXX 320
+ K+ ++K + E+ Q A+ + + + +E +
Sbjct: 1578 VQEALQIERDQL-KENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEH-LKEQFET 1635
Query: 321 XXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSI-K 379
E+ + E +LTQ + +N + + R+ L+S + ++I +
Sbjct: 1636 QKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITR 1695
Query: 380 DMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKES 439
D++ + L I + K QE ID LR + E + ++ ++L+
Sbjct: 1696 DLEKQEELKIVHM------------HLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSND 1743
Query: 440 ILETKQC-VQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXX 498
L+ + +Q+EL L+ ++ I++ + ++ EK +++ ++ L A
Sbjct: 1744 ALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQ 1803
Query: 499 XXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMIN 558
+ S+M+ +++ + +++L +NLN + ++
Sbjct: 1804 ELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLE----IENLN-LAQKLH 1858
Query: 559 QQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMN 618
+ +++ + K ++ +T + E +L ES+ E + + ++E+K +EH
Sbjct: 1859 ENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKE 1918
Query: 619 IINLLHNKLELRNEADIDVIITLAKYKKSL 648
++ L K+ + D+ L K K L
Sbjct: 1919 TVDKLREKISEKTIQISDIQKDLDKSKDEL 1948
Score = 50.8 bits (116), Expect = 2e-05
Identities = 119/584 (20%), Positives = 235/584 (40%), Gaps = 61/584 (10%)
Query: 42 QEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSP 101
+E+ T +K + + ++ +++ + L N++ K++ +K+ A E ++ + K
Sbjct: 1764 KEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQ---EKIQELKANEHQLITLKKDVN 1820
Query: 102 EQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLM 161
E ++ E + L+ D +T ++ N+ +L K E L + K ++ ++L
Sbjct: 1821 ETQKKV---SEMEQLKKQIKDQSLTLSKLEIENL--NLAQKLHENLEEMKSVMKERDNLR 1875
Query: 162 SQEKGISTKTLTMK--IKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQ 219
E+ + + +K ++E A + ++ L R KE + +D LR+ +E
Sbjct: 1876 RVEETLKLERDQLKESLQETKARDLEIQQELKTARM-LSKEHKETVDKLREKISE----- 1929
Query: 220 LRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRL 279
+T ++S DL+ E++K+ +H R ++++
Sbjct: 1930 -KTIQISDIQKDLDKSKDELQKKQDRQNHQVKPEKR-------LLSDGQQHLTESLREKC 1981
Query: 280 SRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELN---KLT 336
SR + LK R +++ E S LE+ + +F +EL+ K
Sbjct: 1982 SRIKELLK----RYSEMDDHYECLNRLSLDLEKEI------------EFQKELSMRVKAN 2025
Query: 337 QSIKD-NTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEI 395
S+ T H+E + A ++ S SY IK+ +HE ++N +
Sbjct: 2026 LSLPYLQTKHIEKLFTANQRC-SMEFHRIMKKLKYVLSYVTKIKEEQHE-SIN-----KF 2078
Query: 396 EKKYNDSIEEKKTLQENIDDLRTD--LLESELRVKDLVRELD-EKESILETKQCVQKELE 452
E + D +E++K L I L+ D + ELR L + +D E IL K + E
Sbjct: 2079 EMDFIDEVEKQKELLIKIQHLQQDCDVPSRELRDLKLNQNMDLHIEEIL--KDFSESEFP 2136
Query: 453 STKTDLEHRKTEIEEYKRLLFE-KGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXX 511
S KT+ + + +E + L E D K K +K I
Sbjct: 2137 SIKTEFQQVLSNRKEMTQFLEEWLNTRFDIEKLKNGIQKENDRICQVNNFFNNRIIAIMN 2196
Query: 512 XXXXXXXXRESQMKSYYEELMNLKNQITQL-REFGAFDNLNDVGNMINQ--QRDKLFELT 568
+ K + ++L +LK + +L + + G +N Q +K +T
Sbjct: 2197 ESTEFEERSATISKEWEQDLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNPHVT 2256
Query: 569 KRQEEYD-EKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNE 611
R + EK++ EN + ES +E + K +KE+++ N+
Sbjct: 2257 SRATQLTTEKIRELENSLHEAKESAMHKESKIIKMQKELEVTND 2300
Score = 48.4 bits (110), Expect = 9e-05
Identities = 118/693 (17%), Positives = 285/693 (41%), Gaps = 44/693 (6%)
Query: 1 MKQEELEIQQNQ-TDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQ 59
+K + ++++Q T L ++E+ + + + K T QE++ + ++EL
Sbjct: 1217 LKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHE-EQELLPNV 1275
Query: 60 NQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHS 119
+V E + T +++LL ++ + L + + +L + Q + E K+L
Sbjct: 1276 KEVSET----QETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQE-SQEEIKSLTKE 1330
Query: 120 TLDNKVTFDVNKLLNIPNS-LVDKCEETLFKRKEIINWFE-SLMSQEKGISTKTLTMKIK 177
DN T + + L + + L + ETL K +E + E SL +EK T + +++
Sbjct: 1331 R-DNLKT--IKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEME 1387
Query: 178 EFNAEND-LLKSSLDQLR-TEFLKEINDIIDCLRKNANETM----ALQLRTKELSCALSD 231
+F ++ LL+ ++ L ++ L+E +D + + K ++ LQ + +L + +
Sbjct: 1388 QFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKE 1447
Query: 232 LNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVE 291
+ ++ E +++ H S ++ +L +L+ ++
Sbjct: 1448 IVAKHLETEEELKVA-HCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQ 1506
Query: 292 RVVQLEAALEQAR----SESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLE 347
+ + E + E + + + + ++ +LT ++++ ++
Sbjct: 1507 EIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQ 1566
Query: 348 DIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH--EMNLNIAKLIEIEKKYNDSIEE 405
+ +E+++ + + + MK E K+ + + + + E
Sbjct: 1567 IMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNET-QEKMCE 1625
Query: 406 KKTLQENIDDLRTDL--LESE-LRVKDLVRE-LDEKESILETKQCVQKELESTKTDLEHR 461
+ L+E + + +L +E+E +R+ ++ E L+E S+ + + ++ E+ K + +
Sbjct: 1626 IEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQL 1685
Query: 462 KTEIEEYKRLLFEKGEEIDELKSKLST-EKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXR 520
K + E EK EE+ + L ++ I +
Sbjct: 1686 KENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDAL 1745
Query: 521 ESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQT 580
++Q EEL + + +E D L + ++++ DKL + K E + KLQ
Sbjct: 1746 KAQDLKIQEELRIAHMHLKEQQE--TIDKLRGI---VSEKTDKLSNMQKDLENSNAKLQE 1800
Query: 581 KENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRN-------EA 633
K E+K + + +N+ +K++ + E+ ++ + +L +KLE+ N
Sbjct: 1801 KIQELKANEHQLITLKKDVNETQKKVSEM-EQLKKQIKDQSLTLSKLEIENLNLAQKLHE 1859
Query: 634 DIDVIITLAKYKKSLTLVLEKMSISNRVLKCSL 666
+++ + ++ K + +L V E + + LK SL
Sbjct: 1860 NLEEMKSVMKERDNLRRVEETLKLERDQLKESL 1892
Score = 48.0 bits (109), Expect = 1e-04
Identities = 113/633 (17%), Positives = 249/633 (39%), Gaps = 43/633 (6%)
Query: 2 KQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQ 61
K EEL I ++ D E ++++ + +I K K + + T + + K +
Sbjct: 746 KSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTK----DDLATTQSNYKSTDQEFQN 801
Query: 62 VMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTL 121
L+ ++ + +++N I+N++K + Q G L + T
Sbjct: 802 FKTLHMDFEQKYKMVLEENERMNQ------EIVNLSKEA--QKFDSSLGALKTELSYKTQ 853
Query: 122 D-NKVTFDVNKLLNIPNSLVDKCE------ETLFKRKEIINWFESLMSQEKGISTKTLTM 174
+ + T +V + LN L ++ E +T+ + K +I E L Q+ KTLT
Sbjct: 854 ELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLIT--EKL--QQTLEEVKTLTQ 909
Query: 175 KIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLR--KNANETMALQLRT-KELSCALSD 231
+ + + L+ DQL+++ +N ID +NA E++ T L +S+
Sbjct: 910 EKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISE 969
Query: 232 LNTQNAEMRKQI-HSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNV 290
++N M + + D + + + + + ++ + +
Sbjct: 970 EVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLI 1029
Query: 291 ERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDF---DQELNKLTQSIKDNTTHLE 347
+ +L+ LE +E L+ + E+ EL K + + H
Sbjct: 1030 QEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNH-- 1087
Query: 348 DIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAK-LIEIEKKYNDSIEEK 406
A+ +E S ++ +++ + ++ LN+ + + E++KK N+ IE
Sbjct: 1088 --AIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQL-LNVQEEMSEMQKKINE-IENL 1143
Query: 407 KTLQENIDDLRTDLLESE-LRVKDLVRELDEKESILETKQCVQKELE-STKTDLEHRKTE 464
K +N +L + +E+E L + + E E+ + ++ V KEL+ S +T+ +H +
Sbjct: 1144 KNELKN-KELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGY 1202
Query: 465 IEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQM 524
I E + + EE+ L + D + ++
Sbjct: 1203 IREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEI 1262
Query: 525 KSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENE 584
+EE L N + ++ E + +N++ + Q K R E +L K E
Sbjct: 1263 PVLHEEQELLPN-VKEVSE--TQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQE 1319
Query: 585 IKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHM 617
+ ++S+T++ L ++ +++ +++ +EH+
Sbjct: 1320 SQEEIKSLTKERDNLKTIKEALEVKHDQLKEHI 1352
Score = 48.0 bits (109), Expect = 1e-04
Identities = 126/656 (19%), Positives = 267/656 (40%), Gaps = 68/656 (10%)
Query: 37 LKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNV 96
LKT K ++ +E+++R N++ +L L N ++ + ++ L + + +
Sbjct: 844 LKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEE 903
Query: 97 AKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINW 156
K ++ L E +E L + + VN ++ L + E +L + +E IN
Sbjct: 904 VKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALE-SLKQHQETINT 962
Query: 157 FESLMSQE--KGISTKTLTMKIK-EFNAENDLL--KSSLDQLRTEFLK---EINDIIDCL 208
+S +S+E + + + T + K EF + + K L+ T+ L + N+II+
Sbjct: 963 LKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQ 1022
Query: 209 RKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXX 268
RK +L EL L + + +++ + + N+
Sbjct: 1023 RK----IFSLIQEKNELQQMLESVIAEKEQLKTDLKE-NIEMTIENQEELRLLGDELKKQ 1077
Query: 269 XXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDF 328
+ K+ + E +L +R+ ++E L++ + ++ + +
Sbjct: 1078 QEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKI 1137
Query: 329 DQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLN 388
+ E+ L +K+ LE + R +L + N++ +++K +
Sbjct: 1138 N-EIENLKNELKNKELTLEHMETERLEL--------------AQKLNENYEEVK-----S 1177
Query: 389 IAKLIEIEKKYNDSIE-EKKTLQENIDDLRTDLLESELRVKDLVRELDE-KESILETKQC 446
I K ++ K+ S E E+ L+ I ++ L+++ +K L E +E+I E ++
Sbjct: 1178 ITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRS 1237
Query: 447 V-QKELESTKT-DLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXX 504
V +K + T DLE T+++E +L E+ E + +K T++ + ++
Sbjct: 1238 VSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTT 1297
Query: 505 XXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKL 564
+ + EE+ +L T+ R DNL + + + D+L
Sbjct: 1298 KDSTTLARIEMERLRLNEKFQESQEEIKSL----TKER-----DNLKTIKEALEVKHDQL 1348
Query: 565 FELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKE---IKMLNEKEEEHMNIIN 621
+E E L ++ ES ++QE LN KEK+ K+++E E+
Sbjct: 1349 ------KEHIRETLA-------KIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSA 1395
Query: 622 LLHNKLEL-----RNEADIDVIITLAKYKKSLTLVLEKMSISNRVLKCSLLGVVTQ 672
LL ++E+ R + D + ++AK K L + E + + LK ++ +V +
Sbjct: 1396 LLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAK 1451
Score = 45.6 bits (103), Expect = 6e-04
Identities = 58/250 (23%), Positives = 105/250 (42%), Gaps = 25/250 (10%)
Query: 393 IEIEKKYNDSIEEKKTLQENIDD-LRTDLL---ESELRVKDLVRELD---EKESILETKQ 445
+++EK+ + E L ID + DLL E E ++ DL +EL+ E+ L +
Sbjct: 664 VDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEV 723
Query: 446 CVQKELESTKTDLEHRKTEI----EEYKRLLFEKGEEIDELKSKLSTEKAI-------KD 494
+ EL+S +++E + EI EE + EK + E+ K S + + KD
Sbjct: 724 ILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKD 783
Query: 495 IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQL-REFGAFDNLNDV 553
E + K EE + +I L +E FD+ +
Sbjct: 784 DLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDS--SL 841
Query: 554 GNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKE 613
G + + K EL ++ E E+L NE+++L E + ++ L E+E ++ EK
Sbjct: 842 GALKTELSYKTQELQEKTREVQERL----NEMEQLKEQLENRDSTLQTVEREKTLITEKL 897
Query: 614 EEHMNIINLL 623
++ + + L
Sbjct: 898 QQTLEEVKTL 907
Score = 44.0 bits (99), Expect = 0.002
Identities = 90/491 (18%), Positives = 201/491 (40%), Gaps = 34/491 (6%)
Query: 7 EIQQNQTDGCLYEDLNEQESITSESHKITKLK-TVWQEKMVTFEKSKKELEDRQNQVMEL 65
E+ Q+++D L E++ E + E+ + K+ +E+ T + + L +++ ++ +
Sbjct: 1432 EVLQSESDQ-LKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTI 1490
Query: 66 YASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKV 125
L + K++ Q++ E+ +I ++++ E++ +L E + + S L +
Sbjct: 1491 QKQLEAINDKLQNKIQEI-YEKEEQFNIKQISEVQ-EKVNELKQFKEHRKAKDSALQSIE 1548
Query: 126 TFDVNKLLNIPNSLVDKCEET--LFKRKEIINWFESLMSQEKGI---STKTLTMKIKEFN 180
+ K+L + N L + EE + K KE + + + E+ +TK + K+KE
Sbjct: 1549 S----KMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQ 1604
Query: 181 A-ENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKEL-SCALSDLNTQNAE 238
E LK + E + EI + K ET L L E + L+ + +N E
Sbjct: 1605 EKEYQFLKMTAVNETQEKMCEIEHL-----KEQFETQKLNLENIETENIRLTQILHENLE 1659
Query: 239 -MRKQIHSGDHHRPYANR-NXXXXXXXXXXXXXXXXSIMKDRLSRAEHQ-LKTNVERVVQ 295
MR D R + K + H LK + E + +
Sbjct: 1660 EMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDK 1719
Query: 296 LEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREK 355
L + + +E ++++ + +EL +K+ ++ +
Sbjct: 1720 LRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKL----RG 1775
Query: 356 LQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDS---IEEKKTLQEN 412
+ S + N +++ E+ N +LI ++K N++ + E + L++
Sbjct: 1776 IVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQ 1835
Query: 413 IDDLRTDLLESELRVKDLVREL----DEKESILETKQCVQKELESTKTDLEHRKTEIEEY 468
I D L + E+ +L ++L +E +S+++ + +++ E+ K + + K ++E
Sbjct: 1836 IKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQET 1895
Query: 469 KRLLFEKGEEI 479
K E +E+
Sbjct: 1896 KARDLEIQQEL 1906
Score = 39.9 bits (89), Expect = 0.030
Identities = 105/634 (16%), Positives = 245/634 (38%), Gaps = 41/634 (6%)
Query: 42 QEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVA-KLS 100
QE + KE +D Q L + +K + K +L + EEL + + K
Sbjct: 1411 QESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAK-HLETEEELKVAHCCLKEQ 1469
Query: 101 PEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKR----KEIINW 156
E + +L K E ST+ ++ +KL N + +K E+ K+ +E +N
Sbjct: 1470 EETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNE 1529
Query: 157 FESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLD-QLRTEFLKEINDIIDCLRKNANET 215
+ K + +++ K N L +S + Q+ + +E+ + + L+ ++
Sbjct: 1530 LKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQ- 1588
Query: 216 MALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIM 275
L+ TKE+ + + + + K +
Sbjct: 1589 --LKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETE 1646
Query: 276 KDRLSRAEHQLKTNVERVVQLEAALEQARS--ESWSLERTVXXXXXXXXXXXE-DFDQEL 332
RL++ H+ N+E + + + RS E+ +ER + + +EL
Sbjct: 1647 NIRLTQILHE---NLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEEL 1703
Query: 333 NKLTQSIKDNTTHLEDI-ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAK 391
+ +K++ ++ + + EK A + +K ++ E+ +
Sbjct: 1704 KIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLK-IQEELRIAHMH 1762
Query: 392 LIEIEKKYND--SIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQK 449
L E ++ + I +KT + + +++ DL S ++++ ++EL E L T +
Sbjct: 1763 LKEQQETIDKLRGIVSEKT--DKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVN 1820
Query: 450 ELESTKTDLEHRKTEIEEYK-----------RLLFEKGEEIDELKSKLSTEKAIKDIXXX 498
E + +++E K +I++ L + E ++E+KS + ++ +
Sbjct: 1821 ETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEET 1880
Query: 499 XXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNL--NDVGNM 556
+ ++K+ K + +LRE + + +D+
Sbjct: 1881 LKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKD 1940
Query: 557 INQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEH 616
+++ +D EL K+Q+ + +++ ++ + + +TE + KE+ + ++H
Sbjct: 1941 LDKSKD---ELQKKQDRQNHQVKPEKRLLSDGQQHLTESLREKCSRIKELLKRYSEMDDH 1997
Query: 617 MNIINLLHNKLELRNEADIDVIITLAKYKKSLTL 650
+N L L+L E + +++ + K +L+L
Sbjct: 1998 YECLNRL--SLDLEKEIEFQKELSM-RVKANLSL 2028
Score = 36.3 bits (80), Expect = 0.37
Identities = 55/267 (20%), Positives = 115/267 (43%), Gaps = 14/267 (5%)
Query: 392 LIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKEL 451
L EIE + ++ ++ ++ LR D L + L E +E E L+ K + +
Sbjct: 484 LSEIEWNPATKLLNQENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFE 543
Query: 452 ESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA--IK-DIXXXXXXXXXXXXX 508
+ + ++ E+ LL EK ++I +L+ + ++K IK D+
Sbjct: 544 ALERKTKKDQENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQM 603
Query: 509 XXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELT 568
+++ +S + NL+ + +++E + N I + +L
Sbjct: 604 KQTLFDAETVALDAKRESAFLRSENLELK-EKMKELAT--TYKQMENDIQLYQSQLEAKK 660
Query: 569 KRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
K Q + +++LQ+ NEI +L + K K++ E E + ++ L+ ++E
Sbjct: 661 KMQVDLEKELQSAFNEITKLTSLID------GKVPKDLLCNLELEGKITDLQKELNKEVE 714
Query: 629 LRNEADIDVIITLAKYKKSLTLVLEKM 655
NEA + +I L++ KSL +E++
Sbjct: 715 -ENEALREEVILLSEL-KSLPSEVERL 739
>Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein.
Length = 2663
Score = 75.4 bits (177), Expect = 7e-13
Identities = 127/655 (19%), Positives = 278/655 (42%), Gaps = 61/655 (9%)
Query: 2 KQEELEIQQNQTDGCLYEDLNEQESITSESHKITKL--KTVWQEKMVTFEKSKKELEDRQ 59
K+++++ Q D E++ S + ES + K +T++ + V + +K+E +
Sbjct: 587 KEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALD-AKRESAFLR 645
Query: 60 NQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHS 119
++ +EL ++ K + + L ++ L ++ E+ LQ A E L S
Sbjct: 646 SENLELKEKMKELATTYKQMENDIQLYQSQ-LEAKKKMQVDLEKELQ-SAFNEITKLT-S 702
Query: 120 TLDNKVTFDV-------NKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKT- 171
+D KV D+ K+ ++ L + EE R+E+I L+S+ K + ++
Sbjct: 703 LIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVI-----LLSELKSLPSEVE 757
Query: 172 -LTMKIKEFNAENDLLKSSLDQLRTEFL-KE--INDIIDCLRKNANETMALQLRTKELSC 227
L +I++ + E ++ S D+L +E + KE + +++ + K ++ Q K
Sbjct: 758 RLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQ 817
Query: 228 ALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLK 287
+ T + + ++ N+ ++ K LS +L+
Sbjct: 818 EFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGAL-KTELSYKTQELQ 876
Query: 288 TNV----ERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNT 343
ER+ ++E EQ + L+ TV + +E+ LTQ D
Sbjct: 877 EKTREVQERLNEMEQLKEQLENRDSPLQ-TVEREKTLITEKLQQTLEEVKTLTQEKDDLK 935
Query: 344 THLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMK-HEMNLN---------IAKLI 393
E + + R++L+S +++ +K H+ +N +++ +
Sbjct: 936 QLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNL 995
Query: 394 EIEKKYNDSIEEKKTLQENID---DLR---TDLLESELRVKDLVRELDEKESILETKQCV 447
+E+ ++ +E + ID DL T L ++++ +++ + + S+++ K +
Sbjct: 996 HMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNEL 1055
Query: 448 QKELESTKTDLEHRKTEIEEYKRLLFEKGEEI----DELKSKLSTEKAIKDIXXXXXXXX 503
Q+ LES + E KT+++E + E EE+ DELK + K+
Sbjct: 1056 QQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGEL 1115
Query: 504 XXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDK 563
+ Q++ ++L+N++ +++++++ +N++ N+ N+ ++K
Sbjct: 1116 SRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQK-----KINEIENLKNELKNK 1170
Query: 564 LFELTKRQEEYDE-KLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHM 617
ELT E + +L K NE V+S+T++ VL KE++ E E +H+
Sbjct: 1171 --ELTLEHMETERLELAQKLNENYEEVKSITKERKVL----KELQKSFETERDHL 1219
Score = 57.6 bits (133), Expect = 1e-07
Identities = 84/514 (16%), Positives = 205/514 (39%), Gaps = 29/514 (5%)
Query: 147 LFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQL-RTEFLKEINDII 205
L +++E IN +S+++ T+ T++ K+ A ND L++ + ++ E I I
Sbjct: 1486 LKEQEETINELRVNLSEKE---TEISTIQ-KQLEAINDKLQNKIQEIYEKEEQLNIKQIS 1541
Query: 206 DCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXX 265
+ +++N NE + K AL + ++ E+ ++ +
Sbjct: 1542 E-VQENVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQE 1600
Query: 266 XXXXXXXSIMKDRLSRAEHQLKTNVERVVQL--EAALEQARSESWSLERTVXXXXXXXXX 323
+ K+ ++K + E+ Q A+ + + + +E +
Sbjct: 1601 ALQIERDQL-KENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEH-LKEQFETQKL 1658
Query: 324 XXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSI-KDMK 382
E+ + E +LTQ + +N + + R+ L+S + ++I +D++
Sbjct: 1659 NLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLE 1718
Query: 383 HEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILE 442
+ L I + K QE ID LR + E + ++ ++L+ L+
Sbjct: 1719 KQEELKIVHM------------HLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALK 1766
Query: 443 TKQC-VQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXX 501
+ +Q+EL L+ ++ I++ + ++ EK +++ ++ L A
Sbjct: 1767 AQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELK 1826
Query: 502 XXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQR 561
+ S+M+ +++ + +++L +NLN + +++
Sbjct: 1827 ANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLE----IENLN-LAQELHENL 1881
Query: 562 DKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIIN 621
+++ + K ++ +T + E +L ES+ E + + ++E+K +EH ++
Sbjct: 1882 EEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVD 1941
Query: 622 LLHNKLELRNEADIDVIITLAKYKKSLTLVLEKM 655
L K+ + D+ L K K L ++++
Sbjct: 1942 KLREKISEKTIQISDIQKDLDKSKDELQKKIQEL 1975
Score = 51.6 bits (118), Expect = 9e-06
Identities = 113/624 (18%), Positives = 253/624 (40%), Gaps = 47/624 (7%)
Query: 7 EIQQNQTDGCLYEDLNEQESITSESHKITKLK-TVWQEKMVTFEKSKKELEDRQNQVMEL 65
E+ Q+++D L E++ E + E+ + K+ +E+ T + + L +++ ++ +
Sbjct: 1452 EVLQSESDQ-LKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTI 1510
Query: 66 YASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKV 125
L + K++ Q++ E+L+I ++++ E + +L E + + S L +
Sbjct: 1511 QKQLEAINDKLQNKIQEI-YEKEEQLNIKQISEVQ-ENVNELKQFKEHRKAKDSALQSIE 1568
Query: 126 TFDVNKLLNIPNSLVDKCEET--LFKRKEIINWFESLMSQEKGI---STKTLTMKIKEFN 180
+ K+L + N L + EE + K KE + + + E+ +TK + K+KE
Sbjct: 1569 S----KMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQ 1624
Query: 181 A-ENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKEL-SCALSDLNTQNAE 238
E LK + E + EI + K ET L L E + L+ + +N E
Sbjct: 1625 EKEYQFLKMTAVNETQEKMCEIEHL-----KEQFETQKLNLENIETENIRLTQILHENLE 1679
Query: 239 -MRKQIHSGDHHRPYANR-NXXXXXXXXXXXXXXXXSIMKDRLSRAEHQ-LKTNVERVVQ 295
MR D R + K + H LK + E + +
Sbjct: 1680 EMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDK 1739
Query: 296 LEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREK 355
L + + +E ++++ + +EL +K+ ++ +
Sbjct: 1740 LRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKL----RG 1795
Query: 356 LQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDS---IEEKKTLQEN 412
+ S + N +++ E+ N +LI ++K N++ + E + L++
Sbjct: 1796 IVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQ 1855
Query: 413 IDDLRTDLLESELRVKDLVREL----DEKESILETKQCVQKELESTKTDLEHRKTEIEEY 468
I D L + E+ +L +EL +E +S+++ + +++ E+ K + + K ++E
Sbjct: 1856 IKDQSLTLSKLEIENLNLAQELHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQET 1915
Query: 469 KRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYY 528
K E + ELK+ K K+ + +++
Sbjct: 1916 KARDLEIQQ---ELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKI 1972
Query: 529 EELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQE-EYDEKLQTKENEIKR 587
+EL + Q+ +++E DV NM +++ +++ +L K+ E Y K + ++ +
Sbjct: 1973 QELQKKELQLLRVKE--------DV-NMSHKKINEMEQLKKQFEPNYLCKCEMDNFQLTK 2023
Query: 588 LVESMTEQEHVLNKKEKEIKMLNE 611
+ E+ ++ K+ E++ + E
Sbjct: 2024 KLHESLEEIRIVAKERDELRRIKE 2047
Score = 50.0 bits (114), Expect = 3e-05
Identities = 119/693 (17%), Positives = 287/693 (41%), Gaps = 44/693 (6%)
Query: 1 MKQEELEIQQNQ-TDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQ 59
+K + ++++Q T L ++E+ + + + K T QE++ + ++EL
Sbjct: 1237 LKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHE-EQELLPNV 1295
Query: 60 NQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHS 119
+V E + T +++LL ++ + L + + +L + Q + E K+L
Sbjct: 1296 KKVSET----QETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQE-SQEEIKSLTKE 1350
Query: 120 TLDNKVTFDVNKLLNIPNS-LVDKCEETLFKRKEIINWFE-SLMSQEKGISTKTLTMKIK 177
DN T + + L + + L + ETL K +E + E SL +EK T + +++
Sbjct: 1351 R-DNLKT--IKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEME 1407
Query: 178 EFNAEND-LLKSSLDQLR-TEFLKEINDIIDCLRKNANETM----ALQLRTKELSCALSD 231
+F ++ LL+ ++ L ++ L+E +D + + K ++ LQ + +L + +
Sbjct: 1408 QFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKE 1467
Query: 232 LNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVE 291
+ ++ E +++ H S ++ +L +L+ ++
Sbjct: 1468 IVAKHLETEEELKVA-HCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQ 1526
Query: 292 RVVQLEAALEQAR----SESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLE 347
+ + E L + E+ + + + + ++ +LT ++++ ++
Sbjct: 1527 EIYEKEEQLNIKQISEVQENVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQ 1586
Query: 348 DIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH--EMNLNIAKLIEIEKKYNDSIEE 405
+ +E+++ + + + MK E K+ + + + + E
Sbjct: 1587 IMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNET-QEKMCE 1645
Query: 406 KKTLQENIDDLRTDL--LESE-LRVKDLVRE-LDEKESILETKQCVQKELESTKTDLEHR 461
+ L+E + + +L +E+E +R+ ++ E L+E S+ + + ++ E+ K + +
Sbjct: 1646 IEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQL 1705
Query: 462 KTEIEEYKRLLFEKGEEIDELKSKLST-EKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXR 520
K + E EK EE+ + L ++ I +
Sbjct: 1706 KENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDAL 1765
Query: 521 ESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQT 580
++Q EEL + + +E D L + ++++ DKL + K E + KLQ
Sbjct: 1766 KAQDLKIQEELRIAHMHLKEQQE--TIDKLRGI---VSEKTDKLSNMQKDLENSNAKLQE 1820
Query: 581 KENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRN-------EA 633
K E+K + + +N+ +K++ + E+ ++ + +L +KLE+ N
Sbjct: 1821 KIQELKANEHQLITLKKDVNETQKKVSEM-EQLKKQIKDQSLTLSKLEIENLNLAQELHE 1879
Query: 634 DIDVIITLAKYKKSLTLVLEKMSISNRVLKCSL 666
+++ + ++ K + +L V E + + LK SL
Sbjct: 1880 NLEEMKSVMKERDNLRRVEETLKLERDQLKESL 1912
Score = 48.4 bits (110), Expect = 9e-05
Identities = 120/626 (19%), Positives = 250/626 (39%), Gaps = 57/626 (9%)
Query: 20 DLNEQESITSESHK-ITKLKTVWQEKMVTFEKSKKELE-DRQNQVMELYASLRNTHRKMK 77
+++ E++ K I LK +E V+ E + +E D+ Q++E L+ + K
Sbjct: 337 EVSTDEALLKRYRKEIMDLKKQLEE--VSLETRAQAMEKDQLAQLLEEKDLLQKVQNE-K 393
Query: 78 LLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLD--NKVTFDVNKLLNI 135
+ L ++ L + K ++ + C G K + D N T K +
Sbjct: 394 IENLTRMLVTSSSLTLQQELKAKRKRRVTWCLGKINKMKNSNYADQFNIPTNITTKTHKL 453
Query: 136 PNSLVDKCEETLFKRKEII-NWFESLMSQEKGISTKTLTMK-----IKEFNAENDLLKSS 189
+L+ + +E++ ++ N ++L E +TK L + + A+ D L
Sbjct: 454 SINLLREIDESVCSESDVFSNTLDTLSEIEWNPATKLLNQENIESELNSLRADYDNLVLD 513
Query: 190 LDQLRTEFLKEINDIIDCLRKNANETMALQLRTK---ELSCALSDLNTQNAEMRKQIHSG 246
+QLRTE KE ++ + + +E AL+ +TK E+ N +N +++++
Sbjct: 514 YEQLRTE--KEEMELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHREVYNQ 571
Query: 247 DHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVV---QLEAALEQA 303
D +++ I +L + L ++E + Q++ L A
Sbjct: 572 DLENELSSK-VELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDA 630
Query: 304 RSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQ-----S 358
+ + +R E +EL + ++++ + A++K+Q
Sbjct: 631 ETVALDAKRESAFLRSENLELKEKM-KELATTYKQMENDIQLYQSQLEAKKKMQVDLEKE 689
Query: 359 XXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRT 418
S K KD+ + L K+ +++K+ N +EE + L+E + L +
Sbjct: 690 LQSAFNEITKLTSLIDGKVPKDLLCNLELE-GKITDLQKELNKEVEENEALREEVI-LLS 747
Query: 419 DLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEE 478
+L V+ L +E+ +K E + E + +++ H+++ ++ LL E G+
Sbjct: 748 ELKSLPSEVERLRKEIQDKS---EELHIITSEKDKLFSEVVHKESRVQG---LLEEIGKT 801
Query: 479 IDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQI 538
D+L + S K+ E + K EE + +I
Sbjct: 802 KDDLATTQSNYKSTDQEFQNFKTLHMDF--------------EQKYKMVLEENERMNQEI 847
Query: 539 TQL-REFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEH 597
L +E FD+ +G + + K EL ++ E E+L NE+++L E + ++
Sbjct: 848 VNLSKEAQKFDS--SLGALKTELSYKTQELQEKTREVQERL----NEMEQLKEQLENRDS 901
Query: 598 VLNKKEKEIKMLNEKEEEHMNIINLL 623
L E+E ++ EK ++ + + L
Sbjct: 902 PLQTVEREKTLITEKLQQTLEEVKTL 927
Score = 43.2 bits (97), Expect = 0.003
Identities = 111/609 (18%), Positives = 231/609 (37%), Gaps = 37/609 (6%)
Query: 27 ITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLP 86
+ + I KL+ + EK +K+LE+ ++ E L+ ++ L + VN
Sbjct: 1783 LKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNET 1842
Query: 87 SAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSL--VDKCE 144
+ + + K +Q L L +E+ L ++ ++ ++ ++ + + E
Sbjct: 1843 QKKVSEMEQLKKQIKDQSLTL----SKLEIENLNLAQELHENLEEMKSVMKERDNLRRVE 1898
Query: 145 ETL-FKRKEIINWFESLMSQEKGIST--KTLTMKIKEFNAENDLLKSSLDQLR---TEFL 198
ETL +R ++ + +++ I KT M KE D L+ + + ++
Sbjct: 1899 ETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQ 1958
Query: 199 KEINDIIDCLRKNANETMALQL---RTKE-LSCALSDLNTQNAEMRKQIHSGDHHRPYAN 254
K+++ D L+K E +L R KE ++ + +N +++KQ + +
Sbjct: 1959 KDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEME-QLKKQFEPNYLCKCEMD 2017
Query: 255 RNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTV 314
+ +D L R + LK ++ + + ++ ++
Sbjct: 2018 NFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIARDRQNHQVKPEK 2077
Query: 315 XXXXXXXXXXXEDFDQELNKLTQSIK---DNTTHLEDI-ALAREKLQSXXXXXXXXXXXX 370
E ++ +++ + +K + H E + L+ + +
Sbjct: 2078 RLLSDGQQHLMESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIEFHRIMKKLKY 2137
Query: 371 SASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTD--LLESELRVK 428
SY IK+ +HE + + E + D +E++K L I L+ D + ELR
Sbjct: 2138 VLSYVTKIKEEQHEC------INKFEMDFIDEVEKQKELLIKIQHLQQDCDVPSRELRDL 2191
Query: 429 DLVRELD-EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFE-KGEEIDELKSKL 486
L + +D E IL K + E S KT+ + + +E + L E D K K
Sbjct: 2192 KLNQNMDLHIEEIL--KDFSESEFPSIKTEFQQVLSNRKEMTQFLEEWLNTRFDIEKLKN 2249
Query: 487 STEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQL-REFG 545
+K I + K + ++L +LK + +L + +
Sbjct: 2250 GIQKENDRICQVNNFFNNRIIAIMNESTEFEERSATISKEWEQDLKSLKEKNEKLFKNYQ 2309
Query: 546 AFDNLNDVGNMINQ--QRDKLFELTKRQEEYD-EKLQTKENEIKRLVESMTEQEHVLNKK 602
G +N Q +K +T R + EK++ EN + ES +E + K
Sbjct: 2310 TLKTSLASGAQVNPTTQDNKNPHVTSRATQLTTEKIRELENSLHEAKESAMHKESKIIKM 2369
Query: 603 EKEIKMLNE 611
+KE+++ N+
Sbjct: 2370 QKELEVTND 2378
Score = 36.7 bits (81), Expect = 0.28
Identities = 62/276 (22%), Positives = 125/276 (45%), Gaps = 27/276 (9%)
Query: 395 IEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESI-LETKQCVQ----K 449
IE + N + L + + LRT+ E EL++K+ +LDE E++ +TK+ +
Sbjct: 496 IESELNSLRADYDNLVLDYEQLRTEKEEMELKLKE-KNDLDEFEALERKTKKDQEMQLIH 554
Query: 450 ELESTKTDLEHR-------KTEIEEYKRLLFEKGEEIDELKSKLSTEKA--IK-DIXXXX 499
E+ + K ++HR + E+ LL EK ++I +L+ + ++K IK D+
Sbjct: 555 EISNLKNLVKHREVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYSL 614
Query: 500 XXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQ 559
+++ +S + NL+ + +++E + N I
Sbjct: 615 ESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELK-EKMKELAT--TYKQMENDIQL 671
Query: 560 QRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNI 619
+ +L K Q + +++LQ+ NEI +L + K K++ E E + ++
Sbjct: 672 YQSQLEAKKKMQVDLEKELQSAFNEITKLTSLID------GKVPKDLLCNLELEGKITDL 725
Query: 620 INLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKM 655
L+ ++E NEA + +I L++ KSL +E++
Sbjct: 726 QKELNKEVE-ENEALREEVILLSEL-KSLPSEVERL 759
>BC046212-1|AAH46212.1| 364|Homo sapiens Similar to cytomatrix
protein p110 protein.
Length = 364
Score = 69.7 bits (163), Expect = 3e-11
Identities = 56/259 (21%), Positives = 118/259 (45%), Gaps = 11/259 (4%)
Query: 382 KHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESIL 441
+ ++N+ K+ ++++ D ++ L++ + L+TD ++ + L L EKE I+
Sbjct: 9 ERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERII 68
Query: 442 ETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS-TEKAIKDIXXXXX 500
E + E + D R EIE +++ + E+++ L+++L+ E ++ D+
Sbjct: 69 ERLK------EQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHAS 122
Query: 501 XXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQL--REFGAFDNLNDVGNMIN 558
E + + + LK Q QL + + N+ D M
Sbjct: 123 SLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKQAEQLFNQMYNPAHNIEDDSRMNP 182
Query: 559 QQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKML-NEKEEEHM 617
+ D++ +L K Y ++ + E+ RL+E + E E+ N K+K+I L ++++
Sbjct: 183 EFADQIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNK 242
Query: 618 NIINLLHN-KLELRNEADI 635
+ NL HN +LE + A +
Sbjct: 243 KVANLKHNQQLEKKKNAQL 261
>BC112391-1|AAI12392.1| 957|Homo sapiens ELKS/RAB6-interacting/CAST
family member 2 protein.
Length = 957
Score = 68.9 bits (161), Expect = 6e-11
Identities = 125/656 (19%), Positives = 256/656 (39%), Gaps = 47/656 (7%)
Query: 3 QEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQV 62
Q +L+ Q + D L ++L+ ++S S + +KT W ++ +KE R + +
Sbjct: 151 QAQLKELQREND-LLRKELDIKDSKLGSS--MNSIKTFWSPELKKERVLRKEEAARMSVL 207
Query: 63 MELY--ASLRNTHRKMKLLGQKVNLPSAEEL-HIMNVA---KLSPEQLLQLCAGGEPKAL 116
E + N H ++ + + L + +L H++ + + ++L +
Sbjct: 208 KEQMRVSHEENQHLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQ 267
Query: 117 EHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTL---- 172
K F + K L ++ ++TL R E I ++ Q KG+ +K+L
Sbjct: 268 AEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEML-QSKGLPSKSLEDDN 326
Query: 173 --TMKIKEFNAENDLLKSSLDQLRTE--FLKEINDIIDCLRKNANETMALQ--LRTKELS 226
T ++ E ++ L+ LDQ E L+E L+ +T ALQ + K+
Sbjct: 327 ERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTK 386
Query: 227 CALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQL 286
A + N ++ E Q+ + N MK ++ + + +L
Sbjct: 387 IASLERNIRDLEDEIQMLKANG---VLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQEL 443
Query: 287 KTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHL 346
++ L+ LE +++ ++ + E L +++
Sbjct: 444 SKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAK-EQRAAILQTEVDALRLRLEEK 502
Query: 347 EDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEK 406
E + K ++ + ++N+ K+ ++++ D ++
Sbjct: 503 ESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQL 562
Query: 407 KTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIE 466
L++ + L+TD ++ + L L EKE I+E + E + D R EIE
Sbjct: 563 TNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLK------EQRERDDRERLEEIE 616
Query: 467 EYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKS 526
+++ + E+++ L+++L TEK I R+S++KS
Sbjct: 617 SFRKENKDLKEKVNALQAEL-TEKESSLIDLKEHASSLASAGLK---------RDSKLKS 666
Query: 527 YYEELMNLKNQITQLR-EFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEI 585
+ K + ++L + N+ D M + D++ +L K Y ++ + E+
Sbjct: 667 LEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADQIKQLDKEASYYRDECGKAQAEV 726
Query: 586 KRLVESMTEQEHVLNKKEKEIKMLNEKEEEHM-----NIINLLHN-KLELRNEADI 635
RL+E + E E+ N K+K+I L HM + NL HN +LE + A +
Sbjct: 727 DRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKHNQQLEKKKNAQL 782
Score = 35.9 bits (79), Expect = 0.49
Identities = 60/261 (22%), Positives = 119/261 (45%), Gaps = 30/261 (11%)
Query: 388 NIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESI-----LE 442
+I KL+E+ + + + K +N R ES++ +++ + EKE+I L
Sbjct: 304 SIKKLLEMLQ--SKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELH 361
Query: 443 TKQCVQKELESTK---TDLEHRKTEIEEYKRLLFEKGEEIDELKSK--LSTEKAIKDIXX 497
+ +Q E TK T +E + T+I +R + + +EI LK+ L+TE ++I
Sbjct: 362 RRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQ 421
Query: 498 XXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMI 557
+ Q+K +EL ++++ L+ + L++ +
Sbjct: 422 IEVYKSHSKFMKT---------KIDQLK---QELSKKESELLALQT--KLETLSNQNSDC 467
Query: 558 NQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHM 617
Q + L E +E+ LQT+ + ++ +E E+E LNKK K+++ L E++
Sbjct: 468 KQHIEVLKESLTAKEQRAAILQTEVDALRLRLE---EKESFLNKKTKQLQDLTEEKGTLA 524
Query: 618 NIINLLHNKLELRNEADIDVI 638
I + + LE++ E I+V+
Sbjct: 525 GEIRDMKDMLEVK-ERKINVL 544
>BC111550-1|AAI11551.1| 957|Homo sapiens ERC2 protein protein.
Length = 957
Score = 68.9 bits (161), Expect = 6e-11
Identities = 125/656 (19%), Positives = 256/656 (39%), Gaps = 47/656 (7%)
Query: 3 QEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQV 62
Q +L+ Q + D L ++L+ ++S S + +KT W ++ +KE R + +
Sbjct: 151 QAQLKELQREND-LLRKELDIKDSKLGSS--MNSIKTFWSPELKKERVLRKEEAARMSVL 207
Query: 63 MELY--ASLRNTHRKMKLLGQKVNLPSAEEL-HIMNVA---KLSPEQLLQLCAGGEPKAL 116
E + N H ++ + + L + +L H++ + + ++L +
Sbjct: 208 KEQMRVSHEENQHLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQ 267
Query: 117 EHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTL---- 172
K F + K L ++ ++TL R E I ++ Q KG+ +K+L
Sbjct: 268 AEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEML-QSKGLPSKSLEDDN 326
Query: 173 --TMKIKEFNAENDLLKSSLDQLRTE--FLKEINDIIDCLRKNANETMALQ--LRTKELS 226
T ++ E ++ L+ LDQ E L+E L+ +T ALQ + K+
Sbjct: 327 ERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTK 386
Query: 227 CALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQL 286
A + N ++ E Q+ + N MK ++ + + +L
Sbjct: 387 IASLERNIRDLEDEIQMLKANG---VLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQEL 443
Query: 287 KTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHL 346
++ L+ LE +++ ++ + E L +++
Sbjct: 444 SKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAK-EQRAAILQTEVDALRLRLEEK 502
Query: 347 EDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEK 406
E + K ++ + ++N+ K+ ++++ D ++
Sbjct: 503 ESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQL 562
Query: 407 KTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIE 466
L++ + L+TD ++ + L L EKE I+E + E + D R EIE
Sbjct: 563 TNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLK------EQRERDDRERLEEIE 616
Query: 467 EYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKS 526
+++ + E+++ L+++L TEK I R+S++KS
Sbjct: 617 SFRKENKDLKEKVNALQAEL-TEKESSLIDLKEHASSLASAGLK---------RDSKLKS 666
Query: 527 YYEELMNLKNQITQLR-EFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEI 585
+ K + ++L + N+ D M + D++ +L K Y ++ + E+
Sbjct: 667 LEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADQIKQLDKEASYYRDECGKAQAEV 726
Query: 586 KRLVESMTEQEHVLNKKEKEIKMLNEKEEEHM-----NIINLLHN-KLELRNEADI 635
RL+E + E E+ N K+K+I L HM + NL HN +LE + A +
Sbjct: 727 DRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKHNQQLEKKKNAQL 782
Score = 35.9 bits (79), Expect = 0.49
Identities = 60/261 (22%), Positives = 119/261 (45%), Gaps = 30/261 (11%)
Query: 388 NIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESI-----LE 442
+I KL+E+ + + + K +N R ES++ +++ + EKE+I L
Sbjct: 304 SIKKLLEMLQ--SKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELH 361
Query: 443 TKQCVQKELESTK---TDLEHRKTEIEEYKRLLFEKGEEIDELKSK--LSTEKAIKDIXX 497
+ +Q E TK T +E + T+I +R + + +EI LK+ L+TE ++I
Sbjct: 362 RRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQ 421
Query: 498 XXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMI 557
+ Q+K +EL ++++ L+ + L++ +
Sbjct: 422 IEVYKSHSKFMKT---------KIDQLK---QELSKKESELLALQT--KLETLSNQNSDC 467
Query: 558 NQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHM 617
Q + L E +E+ LQT+ + ++ +E E+E LNKK K+++ L E++
Sbjct: 468 KQHIEVLKESLTAKEQRAAILQTEVDALRLRLE---EKESFLNKKTKQLQDLTEEKGTLA 524
Query: 618 NIINLLHNKLELRNEADIDVI 638
I + + LE++ E I+V+
Sbjct: 525 GEIRDMKDMLEVK-ERKINVL 544
>AB002376-1|BAA20832.2| 970|Homo sapiens KIAA0378 protein.
Length = 970
Score = 68.9 bits (161), Expect = 6e-11
Identities = 125/656 (19%), Positives = 256/656 (39%), Gaps = 47/656 (7%)
Query: 3 QEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQV 62
Q +L+ Q + D L ++L+ ++S S + +KT W ++ +KE R + +
Sbjct: 164 QAQLKELQREND-LLRKELDIKDSKLGSS--MNSIKTFWSPELKKERVLRKEEAARMSVL 220
Query: 63 MELY--ASLRNTHRKMKLLGQKVNLPSAEEL-HIMNVA---KLSPEQLLQLCAGGEPKAL 116
E + N H ++ + + L + +L H++ + + ++L +
Sbjct: 221 KEQMRVSHEENQHLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQ 280
Query: 117 EHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTL---- 172
K F + K L ++ ++TL R E I ++ Q KG+ +K+L
Sbjct: 281 AEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEML-QSKGLPSKSLEDDN 339
Query: 173 --TMKIKEFNAENDLLKSSLDQLRTE--FLKEINDIIDCLRKNANETMALQ--LRTKELS 226
T ++ E ++ L+ LDQ E L+E L+ +T ALQ + K+
Sbjct: 340 ERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTK 399
Query: 227 CALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQL 286
A + N ++ E Q+ + N MK ++ + + +L
Sbjct: 400 IASLERNIRDLEDEIQMLKANG---VLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQEL 456
Query: 287 KTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHL 346
++ L+ LE +++ ++ + E L +++
Sbjct: 457 SKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAK-EQRAAILQTEVDALRLRLEEK 515
Query: 347 EDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEK 406
E + K ++ + ++N+ K+ ++++ D ++
Sbjct: 516 ESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQL 575
Query: 407 KTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIE 466
L++ + L+TD ++ + L L EKE I+E + E + D R EIE
Sbjct: 576 TNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLK------EQRERDDRERLEEIE 629
Query: 467 EYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKS 526
+++ + E+++ L+++L TEK I R+S++KS
Sbjct: 630 SFRKENKDLKEKVNALQAEL-TEKESSLIDLKEHASSLASAGLK---------RDSKLKS 679
Query: 527 YYEELMNLKNQITQLR-EFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEI 585
+ K + ++L + N+ D M + D++ +L K Y ++ + E+
Sbjct: 680 LEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADQIKQLDKEASYYRDECGKAQAEV 739
Query: 586 KRLVESMTEQEHVLNKKEKEIKMLNEKEEEHM-----NIINLLHN-KLELRNEADI 635
RL+E + E E+ N K+K+I L HM + NL HN +LE + A +
Sbjct: 740 DRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKHNQQLEKKKNAQL 795
Score = 35.9 bits (79), Expect = 0.49
Identities = 60/261 (22%), Positives = 119/261 (45%), Gaps = 30/261 (11%)
Query: 388 NIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESI-----LE 442
+I KL+E+ + + + K +N R ES++ +++ + EKE+I L
Sbjct: 317 SIKKLLEMLQ--SKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELH 374
Query: 443 TKQCVQKELESTK---TDLEHRKTEIEEYKRLLFEKGEEIDELKSK--LSTEKAIKDIXX 497
+ +Q E TK T +E + T+I +R + + +EI LK+ L+TE ++I
Sbjct: 375 RRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQ 434
Query: 498 XXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMI 557
+ Q+K +EL ++++ L+ + L++ +
Sbjct: 435 IEVYKSHSKFMKT---------KIDQLK---QELSKKESELLALQT--KLETLSNQNSDC 480
Query: 558 NQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHM 617
Q + L E +E+ LQT+ + ++ +E E+E LNKK K+++ L E++
Sbjct: 481 KQHIEVLKESLTAKEQRAAILQTEVDALRLRLE---EKESFLNKKTKQLQDLTEEKGTLA 537
Query: 618 NIINLLHNKLELRNEADIDVI 638
I + + LE++ E I+V+
Sbjct: 538 GEIRDMKDMLEVK-ERKINVL 557
>X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein.
Length = 1411
Score = 66.5 bits (155), Expect = 3e-10
Identities = 115/622 (18%), Positives = 260/622 (41%), Gaps = 48/622 (7%)
Query: 17 LYEDLNEQESITSE-SHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRK 75
++ +L+E+ T + ++++++T +Q F++ +++ E+++ ++L + + H K
Sbjct: 363 IHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSK 422
Query: 76 MKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNI 135
LL + L A + +LS E+L+ L+ S L+ ++ V +
Sbjct: 423 --LLETERQLGEAHG-RLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTEL 479
Query: 136 PNSLVDKCEE-----------TLFKRKEIINWFESLMSQ--EKGISTKTLTMKIKEFNAE 182
+ L DK ++ T K +E N E ++ Q +K + L +++
Sbjct: 480 QHQL-DKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKEN 538
Query: 183 NDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQ 242
LL+ + L + + L + + LQ + +L+ L + + + + ++
Sbjct: 539 ISLLEKEREDLYAKIQAGEGETA-VLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQEN 597
Query: 243 IHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIM---KDRLSRAEHQLKTNVERVVQLEAA 299
+H + R S + K+++S+ + Q+K E ++ EAA
Sbjct: 598 LHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAA 657
Query: 300 LEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSX 359
R++ + +D QELNK+T + T L+D +++ S
Sbjct: 658 KTAQRAD-------LQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQD----KQEHCSQ 706
Query: 360 XXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTD 419
S + ++++ ++ A +E++ ++++ LQ+ L TD
Sbjct: 707 LESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQD---LQQQ-RQLNTD 762
Query: 420 LLESELRVKDLVRELD-EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEE 478
L ELR +L ++L+ EKE + T+ +QK+ E+ ++ ++ + T+ EE K++L + E
Sbjct: 763 L---ELRATELSKQLEMEKEIVSSTRLDLQKKSEALES-IKQKLTKQEEEKQILKQDFET 818
Query: 479 IDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQI 538
+ + ++K+ E+ I ++ ++ + L N K++
Sbjct: 819 LSQ-ETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKD-KLSKVSDSLKNSKSEF 876
Query: 539 TQLREFG--AFDNLNDVGNMINQQRDKLFELT-KRQEEYDEKLQTKENEIKRLVESMTEQ 595
+ + G A +L + Q E T K Q+E + L+ ++ +L +
Sbjct: 877 EKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSM 936
Query: 596 EHVLNKKEKEIKMLNEKEEEHM 617
+ L + + +K NEKEE+ +
Sbjct: 937 QEQLIQAQNTLKQ-NEKEEQQL 957
Score = 58.0 bits (134), Expect = 1e-07
Identities = 126/643 (19%), Positives = 265/643 (41%), Gaps = 63/643 (9%)
Query: 27 ITSESHKITKLKTVWQEKMVTFEKSKKELEDR-QNQVMELYASLRNTHRKMKLLGQKVNL 85
+ ++H + + T EK+ +S K+ ++ +QV E A LR ++ L VN
Sbjct: 566 LQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNE 625
Query: 86 PSAEELHIMNVAKLSPEQL-LQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCE 144
+++ +N +K QL +Q+ A E + + N L N+L DK +
Sbjct: 626 LNSQ----LNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQ 681
Query: 145 ETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDI 204
E L K ++ + + Q+K L +KE+ + L+ ++L + +K++
Sbjct: 682 E-LNKITTQLDQVTAKL-QDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQ-IKKLE-- 736
Query: 205 IDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXX 264
D L A++ ALQ ++ +DL + E+ KQ+ +
Sbjct: 737 ADSLEVKASKEQALQDLQQQRQLN-TDLELRATELSKQLEM--------EKEIVSSTRLD 787
Query: 265 XXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXX 324
+K +L++ E + + + E ++ + + L +
Sbjct: 788 LQKKSEALESIKQKLTKQEEEKQILKQ---DFETLSQETKIQHEELNNRIQTTVTELQKV 844
Query: 325 XEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHE 384
+ + + +L+ ++KD + + D +L K S K+ K++KH+
Sbjct: 845 KMEKEALMTELS-TVKDKLSKVSD-SLKNSK--SEFEKENQKGKAAILDLEKTCKELKHQ 900
Query: 385 MNLNIAKLIEIEKKYNDSIEEKKT----LQENIDDLRTDLLESELRVKDLVRELDEKE-S 439
+ + + ++ +K+ S+E++K L+ ++ ++ L++++ +K +E + + +
Sbjct: 901 LQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGN 960
Query: 440 ILETKQCVQ---KELESTKTDLEH---RKTEIE-EYKRLLFEKGEEIDELKSKLST---- 488
I E KQ + K++E+ + +L+ +KTE+E + ++ L + +E+ K K+S
Sbjct: 961 INELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNN 1020
Query: 489 -EKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAF 547
EK+ ++ E ++ E+L++ +NQI +
Sbjct: 1021 YEKS-QETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKL--I 1077
Query: 548 DNLNDVGNMINQQRDK----LFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKE 603
L + Q K L E K ++ ++ KE E+ + E E + ++E
Sbjct: 1078 QELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQE 1137
Query: 604 KEIKMLNEKEEEH-----MNIIN-------LLHNKLELRNEAD 634
KEI LNE+ + H I N L+ KLEL+ +AD
Sbjct: 1138 KEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKAD 1180
Score = 53.2 bits (122), Expect = 3e-06
Identities = 117/633 (18%), Positives = 235/633 (37%), Gaps = 41/633 (6%)
Query: 23 EQESITSESHKITKLKTVWQEKMVT--FEKSKKELEDRQNQVMELYASLRNTHRKMKLLG 80
E +S+ ++ K L+ + Q++ + E EL + E+ +S R +K
Sbjct: 736 EADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEAL 795
Query: 81 QKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLV 140
+ + ++ + K E L Q E K ++H L+N++ V +L +
Sbjct: 796 ESIKQKLTKQEEEKQILKQDFETLSQ-----ETK-IQHEELNNRIQTTVTELQKVKMEKE 849
Query: 141 DKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDL--LKSSLDQLRTEFL 198
E + ++ +SL + + + K + E LK L L
Sbjct: 850 ALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTL 909
Query: 199 KEINDIIDCLRKNANETMALQLRTKELSCALSDL-NT--QNAEMRKQIHSGDHHRPYANR 255
KE ++ L K + L+L + L NT QN + +Q+ + ++
Sbjct: 910 KEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSE 969
Query: 256 NXXXXXXX-------XXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESW 308
+ ++ +L++A +L E++ L+ E+++
Sbjct: 970 QKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFK 1029
Query: 309 SLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXX 368
L+ +D KL+ + +D ++ I + +Q
Sbjct: 1030 QLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQ 1089
Query: 369 XXSASYN------KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQEN-IDDLRTDLL 421
+ K+++D++ E +L +L+ EK IEE K QE I L +L
Sbjct: 1090 DSAKKEQQLQERCKALQDIQKEKSLKEKELVN-EKSKLAEIEEIKCRQEKEITKLNEELK 1148
Query: 422 ESELR-VKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEID 480
+L +K++ D K+ +++ K +Q + +S K +E K + K + ++ EE+
Sbjct: 1149 SHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELK 1208
Query: 481 ----ELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXR-ESQMKSYYEELMNLK 535
E ++KL +E K++ + + +S + L+
Sbjct: 1209 KEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELE 1268
Query: 536 NQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQ 595
Q LR G L +R L E + E EKLQTK E++R +++ T
Sbjct: 1269 KQTDDLR--GEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKLDNTTAA 1326
Query: 596 EHVLNKKEKEIKM-----LNEKEEEHMNIINLL 623
L ++ + +++ LN K E + N +
Sbjct: 1327 VQELGRENQSLQIKHTQALNRKWAEDNEVQNCM 1359
Score = 52.8 bits (121), Expect = 4e-06
Identities = 132/670 (19%), Positives = 259/670 (38%), Gaps = 70/670 (10%)
Query: 2 KQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQ 61
++ +L+ + L + E IT++ ++T QE E KE +++
Sbjct: 661 QRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLS 720
Query: 62 VMELYASLRNTHRKMKLLGQKVNLPSAEELH-IMNVAKLSPEQLLQLCAGGEPKALE-HS 119
+ + L +K++ +V + L + +L+ + L+L A K LE
Sbjct: 721 LEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTD--LELRATELSKQLEMEK 778
Query: 120 TLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEF 179
+ + D+ K S+ K + +++ + FE+L SQE I + L +I+
Sbjct: 779 EIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETL-SQETKIQHEELNNRIQTT 837
Query: 180 NAENDLLKSSLDQLRTEF--LKE-INDIIDCLRKNANETMALQLRTKELSCALSDLNTQN 236
E +K + L TE +K+ ++ + D L+ + +E + ++ A+ DL
Sbjct: 838 VTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSE---FEKENQKGKAAILDLEKTC 894
Query: 237 AEMRKQIH---SGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERV 293
E++ Q+ + + M+++L +A++ LK N +
Sbjct: 895 KELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEE 954
Query: 294 VQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKL----TQSIKDNTTHLEDI 349
QL+ + + + S ++ + + NKL TQ+ ++ E I
Sbjct: 955 QQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKI 1014
Query: 350 ALAR---EKLQSXXXXXXXXXXXXSASYNKSIKDMKH-EMNLNIA--------------- 390
++ + EK Q + + +D+K E L++A
Sbjct: 1015 SVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQN 1074
Query: 391 KLIEIEKKYN-----DSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQ 445
KLI+ K DS ++++ LQE L+ E L+ K+LV E + I E K
Sbjct: 1075 KLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKC 1134
Query: 446 CVQKELESTKTDLEHRK-------TEIEEYKRLLFEKGEEI----DELKSKLSTEK---- 490
+KE+ +L+ K T +++ K+LL ++ E+ D LK+ + EK
Sbjct: 1135 RQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQ 1194
Query: 491 AIKD-IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDN 549
+KD + +E MK + E L QIT L E N
Sbjct: 1195 ILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNE-----N 1249
Query: 550 LNDVGNMINQQRDKLFELTKRQEE-------YDEKLQTKENEIKRLVESMTEQEHVLNKK 602
L V + ++ EL K+ ++ + +Q ++E + L+E + E + K
Sbjct: 1250 LGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKL 1309
Query: 603 EKEIKMLNEK 612
+ ++ L K
Sbjct: 1310 QTKVLELQRK 1319
Score = 50.0 bits (114), Expect = 3e-05
Identities = 84/401 (20%), Positives = 160/401 (39%), Gaps = 30/401 (7%)
Query: 298 AALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQ 357
A L Q + ++ +L+ V E Q L +++ HL A++++
Sbjct: 561 AVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLR---AAQDRVL 617
Query: 358 SXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLR 417
S + S K + + ++ L+ E ++ LQ ++D +
Sbjct: 618 SLETSVNELNSQLNESKEK-VSQLDIQIKAKTELLLSAEAA---KTAQRADLQNHLDTAQ 673
Query: 418 TDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFE--K 475
L + + + + +LD+ + L+ KQ +LES + + + +E+ L K
Sbjct: 674 NALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIK 733
Query: 476 GEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLK 535
E D L+ K S E+A++D+ +E + S +L
Sbjct: 734 KLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEI-VSSTRLDLQKKS 792
Query: 536 NQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQ-EEYDEKLQTKENEIKRL-VES-- 591
+ +++ + ++ Q + L + TK Q EE + ++QT E++++ +E
Sbjct: 793 EALESIKQ--KLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEA 850
Query: 592 -MTEQEHVLNKKEKEIKML-NEKEE-EHMN------IINLLHNKLELRNEADIDVIITLA 642
MTE V +K K L N K E E N I++L EL+++ + + TL
Sbjct: 851 LMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTL- 909
Query: 643 KYKKSLTLVLEKMSISNRVLKCSLLGVVTQ----SRTLRKN 679
K +K L LEK ++ LK L + Q TL++N
Sbjct: 910 KEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQN 950
Score = 48.8 bits (111), Expect = 7e-05
Identities = 82/474 (17%), Positives = 187/474 (39%), Gaps = 23/474 (4%)
Query: 170 KTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCAL 229
++L +++E EN +K D + + +I D K E + ++++
Sbjct: 138 QSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLT 197
Query: 230 SDLNTQNAEMRKQIHSGDHHRP-YANRNXXXXXXXXXXXXXXXXSIMKDRLS-RAEHQLK 287
+LN + A + + + + RP + ++ ++R S + + + K
Sbjct: 198 EELNKE-ATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECK 256
Query: 288 TNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLE 347
+ EA + Q RSE + V + EL + Q++ +N E
Sbjct: 257 KLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVN-ELTQKNQTLTENLLKKE 315
Query: 348 DIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKK 407
E+ + + + ++ ++ + L I + ++ E +
Sbjct: 316 QDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQ 375
Query: 408 TLQENIDDLRTDLLESELRVKDLVRELDEKESI-----LETKQCVQKELESTKTDLEHRK 462
L+E + ++ T + K L ++ +EKE E Q K LE T+ L
Sbjct: 376 KLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLE-TERQLGEAH 434
Query: 463 TEIEEYKRL----LFEKGEEIDELKSKLST-EKAIKDIXXXXXXXXXXXXXXXXXXXXXX 517
++E ++L L +K +++ +L+ KLS E+ +K+
Sbjct: 435 GRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKE----KVTNSTELQHQLDKTKQQH 490
Query: 518 XXRESQMKSYYEELMNLKNQITQ-LREFGAFDN-LNDVGNMINQQRDKLFELTKRQEEYD 575
+++ +S +L +N + Q LR+ G D + ++ ++ + ++ + L K +E+
Sbjct: 491 QEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLY 550
Query: 576 EKLQTKENEIKRLVESMTEQEHVLNKKEKEI-KMLNEKEEEHMNIINLLHNKLE 628
K+Q E E ++ + E+ H L ++ ++ + L + E H LH++++
Sbjct: 551 AKIQAGEGE-TAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQ 603
Score = 46.4 bits (105), Expect = 3e-04
Identities = 125/688 (18%), Positives = 280/688 (40%), Gaps = 55/688 (7%)
Query: 25 ESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVN 84
E + ++ +++T+ + E+ ++L+D ++ YAS T +++ +
Sbjct: 221 EDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATISQLR--SELAK 278
Query: 85 LPSAEELHIMNVAKL--SPEQLLQ----LCAGGEPKALEHSTLDNKVTFDVNKLLNIPNS 138
P +++ + KL S +L Q L K +++ L+ K + NI +
Sbjct: 279 GPQEVAVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQAT 338
Query: 139 LVDKCEETLFKRKEIINWFESLMSQEKGISTK-TLTMKIKEFNAENDLLKSSLDQLRTEF 197
L K + + + SL +S K T K+KE +E +++ L+ EF
Sbjct: 339 LHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSE---VETKYQHLKAEF 395
Query: 198 LKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNX 257
K++ ++ E LQL+++ ++ L+++ E +Q+ H R R
Sbjct: 396 -KQLQQ-----QREEKEQHGLQLQSE-----INQLHSKLLETERQLGEA-HGRLKEQRQL 443
Query: 258 XXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALE---QARSESWSLERTV 314
+ +LSR E QLK V +L+ L+ Q E +L+++
Sbjct: 444 SSEKLMDKEQQVADLQL---KLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQST 500
Query: 315 XXXXXXXXXXXEDFDQELNKLTQSIKDNTTHL----EDIALAREKLQSXXXXXXXXXXXX 370
E +++ Q I++ L E+I+L EK +
Sbjct: 501 TAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLL-EKEREDLYAKIQAGEGE 559
Query: 371 SASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEE-KKTLQENIDDLRTDLLESELRVKD 429
+A N+ +++ H + + +L E K ++S ++ ++ L + + + + L ++ RV
Sbjct: 560 TAVLNQ-LQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLS 618
Query: 430 LVRELDEKESIL-ETKQCV-QKELE-STKTDL----EHRKT--------EIEEYKRLLFE 474
L ++E S L E+K+ V Q +++ KT+L E KT ++ + L +
Sbjct: 619 LETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQD 678
Query: 475 KGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNL 534
K +E++++ ++L A + +++ ++L
Sbjct: 679 KQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEAD 738
Query: 535 KNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTE 594
++ +E A +L + + EL+K+ E E + + ++++ E++
Sbjct: 739 SLEVKASKE-QALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALES 797
Query: 595 QEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEK 654
+ L K+E+E ++L + E + H +L R + + + + K++ L+ E
Sbjct: 798 IKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEA--LMTEL 855
Query: 655 MSISNRVLKCSLLGVVTQSRTLRKNMSG 682
++ +++ K S ++S ++N G
Sbjct: 856 STVKDKLSKVSDSLKNSKSEFEKENQKG 883
>X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein.
Length = 2185
Score = 66.1 bits (154), Expect = 4e-10
Identities = 129/654 (19%), Positives = 259/654 (39%), Gaps = 56/654 (8%)
Query: 20 DLNEQESITS--ESHK--ITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRK 75
+ N++E I S E H+ + + ++W++K+ + +E+ + Q Q E + +K
Sbjct: 1022 ETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKE--QEVAELKQK 1079
Query: 76 MKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNI 135
+ L G + + E + L +L + K+ ++L T L +
Sbjct: 1080 ILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKL 1139
Query: 136 PNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSS------ 189
L +E F +++++ ++++E LT K+K + E LKSS
Sbjct: 1140 EVDLNKSLKENTFLQEQLVEL--KMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNK 1197
Query: 190 -LDQLRTEFLKEINDIIDCLRKNANETMAL-QLRTKELSCALSDLNTQNAEMRKQIHSGD 247
L+ EF K ++ L +T AL + +T EL +S T NA + + H
Sbjct: 1198 SLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNEL-INISSSKT-NAILSRISHC-Q 1254
Query: 248 HHRPYANRNXXXXXXXXXXXXXXXXSIMKDR------LSRAEHQLKTNVERVVQLEAALE 301
H + +++ +A HQL+ ++ ++A +E
Sbjct: 1255 HRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIE 1314
Query: 302 QARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXX 361
+E +L++ Q +L+++I T E++ + ++ S
Sbjct: 1315 SLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSK 1374
Query: 362 XXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDL--RTD 419
S + S K+ A + + K+Y+ EEK L + + DL + D
Sbjct: 1375 QLTDLNVQLQNSISLSEKE---------AAISSLRKQYD---EEKCELLDQVQDLSFKVD 1422
Query: 420 LLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI 479
L E ++ L + D E K+ Q + ++ + ++E + +EK E+I
Sbjct: 1423 TLSKE-KISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQI 1481
Query: 480 DELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQIT 539
+ LK +L + D E+++KS +M L++ IT
Sbjct: 1482 NLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNL------ETELKSQTARIMELEDHIT 1535
Query: 540 QLREFGAFDNLNDVGNMINQQRD-KLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHV 598
Q + ++LN+V NQQ+D + EL ++ + + E + K+N +K E + E+
Sbjct: 1536 Q--KTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQ 1593
Query: 599 -------LNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYK 645
L K+KE++ +N + + L ++LE + A + + A+ K
Sbjct: 1594 VYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQK 1647
Score = 62.9 bits (146), Expect = 4e-09
Identities = 122/652 (18%), Positives = 258/652 (39%), Gaps = 58/652 (8%)
Query: 4 EELEIQQNQTDGCLYEDLNEQES-ITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQV 62
+E ++Q+ T L E L ++ + + S + TKLK ++ V KS KE Q Q+
Sbjct: 1098 KEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQL 1157
Query: 63 MELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLD 122
+EL RK+ L K+ E + + + S + L E K+LE L
Sbjct: 1158 VELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSL-------EDKSLEFKKLS 1210
Query: 123 NKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQ--EKGISTKTLTMKIKEFN 180
++ ++ +L++ K E+IN S + + + T K+KE
Sbjct: 1211 EELAIQLDICCKKTEALLEA------KTNELINISSSKTNAILSRISHCQHRTTKVKEAL 1264
Query: 181 AENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMR 240
S L+ + +E N + ++ ++ + + K + + L T+ ++
Sbjct: 1265 LIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQ 1324
Query: 241 KQIHSGDHHRPYANRNX-XXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAA 299
K+ G+ + + + ++MK+ L + ++ + +++ L
Sbjct: 1325 KE--GGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQ 1382
Query: 300 LEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSX 359
L+ + S + + +D+E +L ++D + ++ L++EK+ +
Sbjct: 1383 LQNSIS--------LSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVD--TLSKEKISAL 1432
Query: 360 XXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTD 419
+ +H+ + + I++E K ++ E+ E I+ L+ +
Sbjct: 1433 EQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQ-IQLELKSKEAYEK----DEQINLLKEE 1487
Query: 420 LLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI 479
L + R L E+++ +S +E K+ + +T+L+ + I E + + +K EI
Sbjct: 1488 LDQQNKRFDCLKGEMEDDKSKMEKKE------SNLETELKSQTARIMELEDHITQKTIEI 1541
Query: 480 DELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQIT 539
+ L L KDI +++++K E+++ L+NQ+
Sbjct: 1542 ESLNEVLKNYNQQKDI------EHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVY 1595
Query: 540 QLR-EFGA-FDNLNDVGNMINQQRDKLFELTKRQE--------EYDEKLQTKENEIKR-L 588
++ E L V + + ++L L R E E K + K IK+ L
Sbjct: 1596 SMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQL 1655
Query: 589 VESMTEQEHVLNK-KEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVII 639
+ M E+E K E + LN K +E +++L KL+ + + +I
Sbjct: 1656 LSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLI 1707
Score = 57.6 bits (133), Expect = 1e-07
Identities = 126/694 (18%), Positives = 269/694 (38%), Gaps = 41/694 (5%)
Query: 3 QEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQV 62
+EEL + ++QTD + ++L E + ++H ++ ++ +E V+ ++++K L+D+ NQ
Sbjct: 704 EEELSVLKDQTDK-MKQEL-EAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQ- 760
Query: 63 MELYASLRNTHRK---MKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHS 119
+EL R+ H K + + ++ +E AKL Q Q + KA E
Sbjct: 761 LELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQ 820
Query: 120 TLDNKVTFDVNKLLNIPNS---LVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKI 176
+ KLL++ L + E ++K++ ++ I + L ++
Sbjct: 821 LAQLQ-----QKLLDLETERILLTKQVAEVEAQKKDVCTELDA-----HKIQVQDLMQQL 870
Query: 177 KEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRK--NANETMALQLRTKELSCALSDLNT 234
++ N+E + SL Q+ L++ N + ++ E M LQ+R + + L
Sbjct: 871 EKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKK-EIEILTQ 929
Query: 235 QNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVV 294
+ + IH + +N +K +L E +LK +E
Sbjct: 930 KLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTA 989
Query: 295 QLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLED-IALAR 353
LE + ++ + + LE + ++ + + L D I++
Sbjct: 990 -LELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWE 1048
Query: 354 EKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKY----NDSIEEKKTL 409
+KL + + ++K ++ L + E+ K+ + +++ TL
Sbjct: 1049 KKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTL 1108
Query: 410 QENIDDLR------TDLLESELRVKDLVRELD-EKESILETKQCVQKELESTKTDLEHRK 462
E + L+ L + E ++K + +L+ + L+ +Q++L K E K
Sbjct: 1109 NELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDK 1168
Query: 463 TEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRES 522
++ E L EE LKS S EK+ K + E+
Sbjct: 1169 RKVSELTSKLKTTDEEFQSLKS--SHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEA 1226
Query: 523 QMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKE 582
+++ EL+N+ + T ++ + + ++ L T E + +L+
Sbjct: 1227 LLEAKTNELINISSSKTN----AILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLT 1282
Query: 583 NEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLA 642
E L S + H L +KE +IK + E + L + + +A + +
Sbjct: 1283 EEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCIT 1342
Query: 643 KYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRTL 676
+ KK L+ + +++ LK + + + S+ L
Sbjct: 1343 QLKKELSENINAVTLMKEELKEKKVEISSLSKQL 1376
Score = 49.2 bits (112), Expect = 5e-05
Identities = 125/641 (19%), Positives = 248/641 (38%), Gaps = 56/641 (8%)
Query: 4 EELEIQQNQT---DGCLYEDLNEQESITSE-----SHKITKLKTV---WQEKMVTFEKSK 52
E+LE+ N++ + L E L E + + E S +KLKT +Q + EKS
Sbjct: 1137 EKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSN 1196
Query: 53 KELEDRQNQVMELYASLRNTHRKMKLLGQKVN-LPSAEELHIMNVAKLSPEQLLQL---C 108
K LED+ + +L L ++ + +K L A+ ++N++ +L C
Sbjct: 1197 KSLEDKSLEFKKLSEELAI---QLDICCKKTEALLEAKTNELINISSSKTNAILSRISHC 1253
Query: 109 AGGEPKALEHSTLD----NKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQE 164
K E + +++ + +L N+L ++ + +E N +S+ +
Sbjct: 1254 QHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADI 1313
Query: 165 KGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKE 224
+ + T+ ++ + N + S + T+ KE+++ I+ + E ++
Sbjct: 1314 ESLVTEKEALQKEGGNQQQ--AASEKESCITQLKKELSENINAVTLMKEELKEKKVEISS 1371
Query: 225 LSCALSDLNTQ---NAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSR 281
LS L+DLN Q + + ++ + R + ++ K+++S
Sbjct: 1372 LSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISA 1431
Query: 282 AEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKD 341
E Q+ + + + + ++ + + + + D+++N L + +
Sbjct: 1432 LE-QVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQ 1490
Query: 342 NTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMN---LNIAKLIEIEKK 398
+ + E +S S I +++ + + I L E+ K
Sbjct: 1491 QNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKN 1550
Query: 399 YNDSIE-EKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTD 457
YN + E K L + + + E + RVK E +EK LE ++ S K +
Sbjct: 1551 YNQQKDIEHKELVQKLQHFQELGEEKDNRVK----EAEEKILTLEN------QVYSMKAE 1600
Query: 458 LEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXX 517
LE +K E+E + K EE+ L+ +L +E A K +
Sbjct: 1601 LETKKKELEHVNLSVKSKEEELKALEDRLESESAAK-LAELKRKAEQKIAAIKKQLLSQM 1659
Query: 518 XXRESQMKSYYEELMNLKNQITQLREFGAF---DNLNDVGN-----MINQQRDKLFELTK 569
+E Q K E ++ N Q RE + L V + +I + K
Sbjct: 1660 EEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYT 1719
Query: 570 RQEEYDEK---LQTKENEIKRLVESMTEQEHVLNK--KEKE 605
QEE D + +T E +I L ++TE+E +L + +EKE
Sbjct: 1720 EQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKE 1760
Score = 41.5 bits (93), Expect = 0.010
Identities = 113/639 (17%), Positives = 243/639 (38%), Gaps = 41/639 (6%)
Query: 22 NEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMK-LLG 80
+E E + S + K + + +++ E+S + ++++ Y L+ +K++ +L
Sbjct: 122 SEAEDLVGNSDSLNKEQLI--QRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILS 179
Query: 81 QKVN------LPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLN 134
Q + EEL + AK ++ + A E K S L +V+ +L N
Sbjct: 180 QSQDKSLRRIAELREELQMDQQAKKHLQE--EFDASLEEKDQYISVLQTQVSLLKQRLRN 237
Query: 135 IPNSL-VDKCEETLFKRKEIINWFESLMSQ-----EKGISTKTLTMKIKEFNAENDLLKS 188
P ++ V K L + E+ E+ S E G S KTL + + +LLK
Sbjct: 238 GPMNVDVLKPLPQLEPQAEVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKR 297
Query: 189 SLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDH 248
+ +++ KE ++ ++ E L R +EL + DL+ AE K I
Sbjct: 298 CKETIQSH--KEQCTLLTSEKEALQEQ--LDERLQELE-KIKDLHM--AEKTKLI---TQ 347
Query: 249 HRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESW 308
R N M + L E ++ R+ Q+ E+ R +
Sbjct: 348 LRDAKNLIEQLEQDKGMVIAETKRQ-MHETLEMKEEEIAQLRSRIKQMTTQGEELREQKE 406
Query: 309 SLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXX 368
ER + ++ KL + + +E + E++
Sbjct: 407 KSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTS-EEERISLQQELSRVKQE 465
Query: 369 XXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVK 428
S + + L+ +L E++ ++ ++ +E + ++ L +S+
Sbjct: 466 VVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTRE--REFQEQMKVALEKSQSEYL 523
Query: 429 DLVRELDEKESILETKQCVQKE--LESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKL 486
+ +E +++ES+ + +QK+ L ++ L + E E Y+ + E ++ KS
Sbjct: 524 KISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLE--KSLQ 581
Query: 487 STEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGA 546
+ KD+ +K + L K Q+ + +
Sbjct: 582 ENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTE 641
Query: 547 FDNLNDVGNMINQQ--RDK--LFE--LTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLN 600
+ L + + +DK +F+ + + E+ EKL K+ E++ L ++E +
Sbjct: 642 MEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARH 701
Query: 601 KKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVII 639
K E+E+ +L ++ ++ + ++ + ++ +D II
Sbjct: 702 KLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSII 740
Score = 40.3 bits (90), Expect = 0.023
Identities = 91/509 (17%), Positives = 197/509 (38%), Gaps = 37/509 (7%)
Query: 5 ELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVME 64
++E + + E N+Q++ + + IT+LK E + K+EL++++ ++
Sbjct: 1312 DIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISS 1371
Query: 65 LYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNK 124
L L + + +++ ++L S +E I ++ K E+ +L + + + TL +
Sbjct: 1372 LSKQLTDLNVQLQ---NSISL-SEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKE 1427
Query: 125 VTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAEND 184
+ ++ + N + ++ + + N + L Q + + +K K ++ N
Sbjct: 1428 KISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLE-LKSKEAYEKDEQIN---- 1482
Query: 185 LLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIH 244
LLK LDQ F ++ D K + L+ K + + +L + +I
Sbjct: 1483 LLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIE 1542
Query: 245 SGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKD---RLSRAEHQLKTNVERVVQLEAALE 301
S + N+ + ++ R+ AE ++ T +V ++A LE
Sbjct: 1543 SLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELE 1602
Query: 302 QARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXX 361
+ E + +V + + E +K + IA +++L S
Sbjct: 1603 TKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAE--QKIAAIKKQLLSQME 1660
Query: 362 XXXXXXXXXSASY----NKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKK--------TL 409
+ S+ N +++ + E+++ KL +E ++++ + T
Sbjct: 1661 EKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTE 1720
Query: 410 QENIDDLRTDLLESELRVKDLVRELDEKESIL-----ETKQCVQKELE------STKTDL 458
QE D E ++ L R L EKE +L E ++ V E L
Sbjct: 1721 QEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKL 1780
Query: 459 EHRKTEIEEYKRLLFEKGEEIDELKSKLS 487
EH + + E + ++ EE++E K S
Sbjct: 1781 EHAEAKQHEDQSMIGHLQEELEEKNKKYS 1809
Score = 32.7 bits (71), Expect = 4.6
Identities = 43/204 (21%), Positives = 89/204 (43%), Gaps = 13/204 (6%)
Query: 43 EKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPE 102
+++V +K + L Q +E+ + R+ K+ ++ +L E H + +L E
Sbjct: 1944 KEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDL---ELKHNSTLKQLMRE 2000
Query: 103 QLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKC-EETLFKRKEIINWFESLM 161
QL A + L+ + +NK + L++ EET K+I + L
Sbjct: 2001 FNTQL-------AQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLK 2053
Query: 162 SQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLR 221
K + L + +E A+ L++ L++L+ ++ +++ + N M LQ +
Sbjct: 2054 RTAKRYE-EILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVT-IMELQTQ 2111
Query: 222 TKELSCALSDLNTQNAEMRKQIHS 245
+ + +SD + E R+QIH+
Sbjct: 2112 LAQKTTLISDSKLKEQEFREQIHN 2135
>U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein.
Length = 2230
Score = 66.1 bits (154), Expect = 4e-10
Identities = 129/654 (19%), Positives = 259/654 (39%), Gaps = 56/654 (8%)
Query: 20 DLNEQESITS--ESHK--ITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRK 75
+ N++E I S E H+ + + ++W++K+ + +E+ + Q Q E + +K
Sbjct: 1022 ETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKE--QEVAELKQK 1079
Query: 76 MKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNI 135
+ L G + + E + L +L + K+ ++L T L +
Sbjct: 1080 ILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKL 1139
Query: 136 PNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSS------ 189
L +E F +++++ ++++E LT K+K + E LKSS
Sbjct: 1140 EVDLNKSLKENTFLQEQLVEL--KMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNK 1197
Query: 190 -LDQLRTEFLKEINDIIDCLRKNANETMAL-QLRTKELSCALSDLNTQNAEMRKQIHSGD 247
L+ EF K ++ L +T AL + +T EL +S T NA + + H
Sbjct: 1198 SLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNEL-INISSSKT-NAILSRISHC-Q 1254
Query: 248 HHRPYANRNXXXXXXXXXXXXXXXXSIMKDR------LSRAEHQLKTNVERVVQLEAALE 301
H + +++ +A HQL+ ++ ++A +E
Sbjct: 1255 HRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIE 1314
Query: 302 QARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXX 361
+E +L++ Q +L+++I T E++ + ++ S
Sbjct: 1315 SLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSK 1374
Query: 362 XXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDL--RTD 419
S + S K+ A + + K+Y+ EEK L + + DL + D
Sbjct: 1375 QLTDLNVQLQNSISLSEKE---------AAISSLRKQYD---EEKCELLDQVQDLSFKVD 1422
Query: 420 LLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI 479
L E ++ L + D E K+ Q + ++ + ++E + +EK E+I
Sbjct: 1423 TLSKE-KISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQI 1481
Query: 480 DELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQIT 539
+ LK +L + D E+++KS +M L++ IT
Sbjct: 1482 NLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNL------ETELKSQTARIMELEDHIT 1535
Query: 540 QLREFGAFDNLNDVGNMINQQRD-KLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHV 598
Q + ++LN+V NQQ+D + EL ++ + + E + K+N +K E + E+
Sbjct: 1536 Q--KTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQ 1593
Query: 599 -------LNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYK 645
L K+KE++ +N + + L ++LE + A + + A+ K
Sbjct: 1594 VYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQK 1647
Score = 62.9 bits (146), Expect = 4e-09
Identities = 122/652 (18%), Positives = 258/652 (39%), Gaps = 58/652 (8%)
Query: 4 EELEIQQNQTDGCLYEDLNEQES-ITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQV 62
+E ++Q+ T L E L ++ + + S + TKLK ++ V KS KE Q Q+
Sbjct: 1098 KEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQL 1157
Query: 63 MELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLD 122
+EL RK+ L K+ E + + + S + L E K+LE L
Sbjct: 1158 VELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSL-------EDKSLEFKKLS 1210
Query: 123 NKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQ--EKGISTKTLTMKIKEFN 180
++ ++ +L++ K E+IN S + + + T K+KE
Sbjct: 1211 EELAIQLDICCKKTEALLEA------KTNELINISSSKTNAILSRISHCQHRTTKVKEAL 1264
Query: 181 AENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMR 240
S L+ + +E N + ++ ++ + + K + + L T+ ++
Sbjct: 1265 LIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQ 1324
Query: 241 KQIHSGDHHRPYANRNX-XXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAA 299
K+ G+ + + + ++MK+ L + ++ + +++ L
Sbjct: 1325 KE--GGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQ 1382
Query: 300 LEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSX 359
L+ + S + + +D+E +L ++D + ++ L++EK+ +
Sbjct: 1383 LQNSIS--------LSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVD--TLSKEKISAL 1432
Query: 360 XXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTD 419
+ +H+ + + I++E K ++ E+ E I+ L+ +
Sbjct: 1433 EQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQ-IQLELKSKEAYEK----DEQINLLKEE 1487
Query: 420 LLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI 479
L + R L E+++ +S +E K+ + +T+L+ + I E + + +K EI
Sbjct: 1488 LDQQNKRFDCLKGEMEDDKSKMEKKE------SNLETELKSQTARIMELEDHITQKTIEI 1541
Query: 480 DELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQIT 539
+ L L KDI +++++K E+++ L+NQ+
Sbjct: 1542 ESLNEVLKNYNQQKDI------EHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVY 1595
Query: 540 QLR-EFGA-FDNLNDVGNMINQQRDKLFELTKRQE--------EYDEKLQTKENEIKR-L 588
++ E L V + + ++L L R E E K + K IK+ L
Sbjct: 1596 SMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQL 1655
Query: 589 VESMTEQEHVLNK-KEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVII 639
+ M E+E K E + LN K +E +++L KL+ + + +I
Sbjct: 1656 LSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLI 1707
Score = 57.6 bits (133), Expect = 1e-07
Identities = 126/694 (18%), Positives = 269/694 (38%), Gaps = 41/694 (5%)
Query: 3 QEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQV 62
+EEL + ++QTD + ++L E + ++H ++ ++ +E V+ ++++K L+D+ NQ
Sbjct: 704 EEELSVLKDQTDK-MKQEL-EAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQ- 760
Query: 63 MELYASLRNTHRK---MKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHS 119
+EL R+ H K + + ++ +E AKL Q Q + KA E
Sbjct: 761 LELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQ 820
Query: 120 TLDNKVTFDVNKLLNIPNS---LVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKI 176
+ KLL++ L + E ++K++ ++ I + L ++
Sbjct: 821 LAQLQ-----QKLLDLETERILLTKQVAEVEAQKKDVCTELDA-----HKIQVQDLMQQL 870
Query: 177 KEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRK--NANETMALQLRTKELSCALSDLNT 234
++ N+E + SL Q+ L++ N + ++ E M LQ+R + + L
Sbjct: 871 EKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKK-EIEILTQ 929
Query: 235 QNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVV 294
+ + IH + +N +K +L E +LK +E
Sbjct: 930 KLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTA 989
Query: 295 QLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLED-IALAR 353
LE + ++ + + LE + ++ + + L D I++
Sbjct: 990 -LELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWE 1048
Query: 354 EKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKY----NDSIEEKKTL 409
+KL + + ++K ++ L + E+ K+ + +++ TL
Sbjct: 1049 KKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTL 1108
Query: 410 QENIDDLR------TDLLESELRVKDLVRELD-EKESILETKQCVQKELESTKTDLEHRK 462
E + L+ L + E ++K + +L+ + L+ +Q++L K E K
Sbjct: 1109 NELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDK 1168
Query: 463 TEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRES 522
++ E L EE LKS S EK+ K + E+
Sbjct: 1169 RKVSELTSKLKTTDEEFQSLKS--SHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEA 1226
Query: 523 QMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKE 582
+++ EL+N+ + T ++ + + ++ L T E + +L+
Sbjct: 1227 LLEAKTNELINISSSKTN----AILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLT 1282
Query: 583 NEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLA 642
E L S + H L +KE +IK + E + L + + +A + +
Sbjct: 1283 EEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCIT 1342
Query: 643 KYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRTL 676
+ KK L+ + +++ LK + + + S+ L
Sbjct: 1343 QLKKELSENINAVTLMKEELKEKKVEISSLSKQL 1376
Score = 49.2 bits (112), Expect = 5e-05
Identities = 125/641 (19%), Positives = 248/641 (38%), Gaps = 56/641 (8%)
Query: 4 EELEIQQNQT---DGCLYEDLNEQESITSE-----SHKITKLKTV---WQEKMVTFEKSK 52
E+LE+ N++ + L E L E + + E S +KLKT +Q + EKS
Sbjct: 1137 EKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSN 1196
Query: 53 KELEDRQNQVMELYASLRNTHRKMKLLGQKVN-LPSAEELHIMNVAKLSPEQLLQL---C 108
K LED+ + +L L ++ + +K L A+ ++N++ +L C
Sbjct: 1197 KSLEDKSLEFKKLSEELAI---QLDICCKKTEALLEAKTNELINISSSKTNAILSRISHC 1253
Query: 109 AGGEPKALEHSTLD----NKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQE 164
K E + +++ + +L N+L ++ + +E N +S+ +
Sbjct: 1254 QHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADI 1313
Query: 165 KGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKE 224
+ + T+ ++ + N + S + T+ KE+++ I+ + E ++
Sbjct: 1314 ESLVTEKEALQKEGGNQQQ--AASEKESCITQLKKELSENINAVTLMKEELKEKKVEISS 1371
Query: 225 LSCALSDLNTQ---NAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSR 281
LS L+DLN Q + + ++ + R + ++ K+++S
Sbjct: 1372 LSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISA 1431
Query: 282 AEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKD 341
E Q+ + + + + ++ + + + + D+++N L + +
Sbjct: 1432 LE-QVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQ 1490
Query: 342 NTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMN---LNIAKLIEIEKK 398
+ + E +S S I +++ + + I L E+ K
Sbjct: 1491 QNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKN 1550
Query: 399 YNDSIE-EKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTD 457
YN + E K L + + + E + RVK E +EK LE ++ S K +
Sbjct: 1551 YNQQKDIEHKELVQKLQHFQELGEEKDNRVK----EAEEKILTLEN------QVYSMKAE 1600
Query: 458 LEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXX 517
LE +K E+E + K EE+ L+ +L +E A K +
Sbjct: 1601 LETKKKELEHVNLSVKSKEEELKALEDRLESESAAK-LAELKRKAEQKIAAIKKQLLSQM 1659
Query: 518 XXRESQMKSYYEELMNLKNQITQLREFGAF---DNLNDVGN-----MINQQRDKLFELTK 569
+E Q K E ++ N Q RE + L V + +I + K
Sbjct: 1660 EEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYT 1719
Query: 570 RQEEYDEK---LQTKENEIKRLVESMTEQEHVLNK--KEKE 605
QEE D + +T E +I L ++TE+E +L + +EKE
Sbjct: 1720 EQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKE 1760
Score = 41.5 bits (93), Expect = 0.010
Identities = 113/639 (17%), Positives = 243/639 (38%), Gaps = 41/639 (6%)
Query: 22 NEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMK-LLG 80
+E E + S + K + + +++ E+S + ++++ Y L+ +K++ +L
Sbjct: 122 SEAEDLVGNSDSLNKEQLI--QRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILS 179
Query: 81 QKVN------LPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLN 134
Q + EEL + AK ++ + A E K S L +V+ +L N
Sbjct: 180 QSQDKSLRRIAELREELQMDQQAKKHLQE--EFDASLEEKDQYISVLQTQVSLLKQRLRN 237
Query: 135 IPNSL-VDKCEETLFKRKEIINWFESLMSQ-----EKGISTKTLTMKIKEFNAENDLLKS 188
P ++ V K L + E+ E+ S E G S KTL + + +LLK
Sbjct: 238 GPMNVDVLKPLPQLEPQAEVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKR 297
Query: 189 SLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDH 248
+ +++ KE ++ ++ E L R +EL + DL+ AE K I
Sbjct: 298 CKETIQSH--KEQCTLLTSEKEALQEQ--LDERLQELE-KIKDLHM--AEKTKLI---TQ 347
Query: 249 HRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESW 308
R N M + L E ++ R+ Q+ E+ R +
Sbjct: 348 LRDAKNLIEQLEQDKGMVIAETKRQ-MHETLEMKEEEIAQLRSRIKQMTTQGEELREQKE 406
Query: 309 SLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXX 368
ER + ++ KL + + +E + E++
Sbjct: 407 KSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTS-EEERISLQQELSRVKQE 465
Query: 369 XXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVK 428
S + + L+ +L E++ ++ ++ +E + ++ L +S+
Sbjct: 466 VVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTRE--REFQEQMKVALEKSQSEYL 523
Query: 429 DLVRELDEKESILETKQCVQKE--LESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKL 486
+ +E +++ES+ + +QK+ L ++ L + E E Y+ + E ++ KS
Sbjct: 524 KISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLE--KSLQ 581
Query: 487 STEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGA 546
+ KD+ +K + L K Q+ + +
Sbjct: 582 ENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTE 641
Query: 547 FDNLNDVGNMINQQ--RDK--LFE--LTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLN 600
+ L + + +DK +F+ + + E+ EKL K+ E++ L ++E +
Sbjct: 642 MEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARH 701
Query: 601 KKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVII 639
K E+E+ +L ++ ++ + ++ + ++ +D II
Sbjct: 702 KLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSII 740
Score = 40.3 bits (90), Expect = 0.023
Identities = 91/509 (17%), Positives = 197/509 (38%), Gaps = 37/509 (7%)
Query: 5 ELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVME 64
++E + + E N+Q++ + + IT+LK E + K+EL++++ ++
Sbjct: 1312 DIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISS 1371
Query: 65 LYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNK 124
L L + + +++ ++L S +E I ++ K E+ +L + + + TL +
Sbjct: 1372 LSKQLTDLNVQLQ---NSISL-SEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKE 1427
Query: 125 VTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAEND 184
+ ++ + N + ++ + + N + L Q + + +K K ++ N
Sbjct: 1428 KISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLE-LKSKEAYEKDEQIN---- 1482
Query: 185 LLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIH 244
LLK LDQ F ++ D K + L+ K + + +L + +I
Sbjct: 1483 LLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIE 1542
Query: 245 SGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKD---RLSRAEHQLKTNVERVVQLEAALE 301
S + N+ + ++ R+ AE ++ T +V ++A LE
Sbjct: 1543 SLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELE 1602
Query: 302 QARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXX 361
+ E + +V + + E +K + IA +++L S
Sbjct: 1603 TKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAE--QKIAAIKKQLLSQME 1660
Query: 362 XXXXXXXXXSASY----NKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKK--------TL 409
+ S+ N +++ + E+++ KL +E ++++ + T
Sbjct: 1661 EKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTE 1720
Query: 410 QENIDDLRTDLLESELRVKDLVRELDEKESIL-----ETKQCVQKELE------STKTDL 458
QE D E ++ L R L EKE +L E ++ V E L
Sbjct: 1721 QEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKL 1780
Query: 459 EHRKTEIEEYKRLLFEKGEEIDELKSKLS 487
EH + + E + ++ EE++E K S
Sbjct: 1781 EHAEAKQHEDQSMIGHLQEELEEKNKKYS 1809
Score = 32.7 bits (71), Expect = 4.6
Identities = 43/204 (21%), Positives = 89/204 (43%), Gaps = 13/204 (6%)
Query: 43 EKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPE 102
+++V +K + L Q +E+ + R+ K+ ++ +L E H + +L E
Sbjct: 1944 KEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDL---ELKHNSTLKQLMRE 2000
Query: 103 QLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKC-EETLFKRKEIINWFESLM 161
QL A + L+ + +NK + L++ EET K+I + L
Sbjct: 2001 FNTQL-------AQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLK 2053
Query: 162 SQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLR 221
K + L + +E A+ L++ L++L+ ++ +++ + N M LQ +
Sbjct: 2054 RTAKRYE-EILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVT-IMELQTQ 2111
Query: 222 TKELSCALSDLNTQNAEMRKQIHS 245
+ + +SD + E R+QIH+
Sbjct: 2112 LAQKTTLISDSKLKEQEFREQIHN 2135
Score = 31.9 bits (69), Expect = 8.0
Identities = 47/224 (20%), Positives = 99/224 (44%), Gaps = 8/224 (3%)
Query: 2 KQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQ 61
+QE+LE++ N T L + N Q + + ++T +T+ + + V E + E+ NQ
Sbjct: 1982 EQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEE-TNQ 2040
Query: 62 VMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPE-QLLQLCAGGEPKALEHST 120
+++ A + ++ +++ L + EE V L + + LQ + + E+
Sbjct: 2041 LLKKIAEKDDDLKRTAKRYEEI-LDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPG 2099
Query: 121 LDNKVTFDVNKLLNIPNSLV--DKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKE 178
DN ++ L +L+ K +E F R++I N + L EK + T+ K
Sbjct: 2100 NDNVTIMELQTQLAQKTTLISDSKLKEQEF-REQIHNLEDRLKKYEKNVYATTVGTPYKG 2158
Query: 179 FNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRT 222
N + + + E+L+++ + + + +TMA + T
Sbjct: 2159 GNLYHTDVSLFGEPTEFEYLRKV--LFEYMMGRETKTMAKVITT 2200
>U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein.
Length = 2083
Score = 66.1 bits (154), Expect = 4e-10
Identities = 129/654 (19%), Positives = 259/654 (39%), Gaps = 56/654 (8%)
Query: 20 DLNEQESITS--ESHK--ITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRK 75
+ N++E I S E H+ + + ++W++K+ + +E+ + Q Q E + +K
Sbjct: 877 ETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKE--QEVAELKQK 934
Query: 76 MKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNI 135
+ L G + + E + L +L + K+ ++L T L +
Sbjct: 935 ILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKL 994
Query: 136 PNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSS------ 189
L +E F +++++ ++++E LT K+K + E LKSS
Sbjct: 995 EVDLNKSLKENTFLQEQLVEL--KMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNK 1052
Query: 190 -LDQLRTEFLKEINDIIDCLRKNANETMAL-QLRTKELSCALSDLNTQNAEMRKQIHSGD 247
L+ EF K ++ L +T AL + +T EL +S T NA + + H
Sbjct: 1053 SLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNEL-INISSSKT-NAILSRISHC-Q 1109
Query: 248 HHRPYANRNXXXXXXXXXXXXXXXXSIMKDR------LSRAEHQLKTNVERVVQLEAALE 301
H + +++ +A HQL+ ++ ++A +E
Sbjct: 1110 HRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIE 1169
Query: 302 QARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXX 361
+E +L++ Q +L+++I T E++ + ++ S
Sbjct: 1170 SLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSK 1229
Query: 362 XXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDL--RTD 419
S + S K+ A + + K+Y+ EEK L + + DL + D
Sbjct: 1230 QLTDLNVQLQNSISLSEKE---------AAISSLRKQYD---EEKCELLDQVQDLSFKVD 1277
Query: 420 LLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI 479
L E ++ L + D E K+ Q + ++ + ++E + +EK E+I
Sbjct: 1278 TLSKE-KISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQI 1336
Query: 480 DELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQIT 539
+ LK +L + D E+++KS +M L++ IT
Sbjct: 1337 NLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNL------ETELKSQTARIMELEDHIT 1390
Query: 540 QLREFGAFDNLNDVGNMINQQRD-KLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHV 598
Q + ++LN+V NQQ+D + EL ++ + + E + K+N +K E + E+
Sbjct: 1391 Q--KTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQ 1448
Query: 599 -------LNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYK 645
L K+KE++ +N + + L ++LE + A + + A+ K
Sbjct: 1449 VYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQK 1502
Score = 62.9 bits (146), Expect = 4e-09
Identities = 122/652 (18%), Positives = 258/652 (39%), Gaps = 58/652 (8%)
Query: 4 EELEIQQNQTDGCLYEDLNEQES-ITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQV 62
+E ++Q+ T L E L ++ + + S + TKLK ++ V KS KE Q Q+
Sbjct: 953 KEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQL 1012
Query: 63 MELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLD 122
+EL RK+ L K+ E + + + S + L E K+LE L
Sbjct: 1013 VELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSL-------EDKSLEFKKLS 1065
Query: 123 NKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQ--EKGISTKTLTMKIKEFN 180
++ ++ +L++ K E+IN S + + + T K+KE
Sbjct: 1066 EELAIQLDICCKKTEALLEA------KTNELINISSSKTNAILSRISHCQHRTTKVKEAL 1119
Query: 181 AENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMR 240
S L+ + +E N + ++ ++ + + K + + L T+ ++
Sbjct: 1120 LIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQ 1179
Query: 241 KQIHSGDHHRPYANRNX-XXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAA 299
K+ G+ + + + ++MK+ L + ++ + +++ L
Sbjct: 1180 KE--GGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQ 1237
Query: 300 LEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSX 359
L+ + S + + +D+E +L ++D + ++ L++EK+ +
Sbjct: 1238 LQNSIS--------LSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVD--TLSKEKISAL 1287
Query: 360 XXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTD 419
+ +H+ + + I++E K ++ E+ E I+ L+ +
Sbjct: 1288 EQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQ-IQLELKSKEAYEK----DEQINLLKEE 1342
Query: 420 LLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI 479
L + R L E+++ +S +E K+ + +T+L+ + I E + + +K EI
Sbjct: 1343 LDQQNKRFDCLKGEMEDDKSKMEKKE------SNLETELKSQTARIMELEDHITQKTIEI 1396
Query: 480 DELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQIT 539
+ L L KDI +++++K E+++ L+NQ+
Sbjct: 1397 ESLNEVLKNYNQQKDI------EHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVY 1450
Query: 540 QLR-EFGA-FDNLNDVGNMINQQRDKLFELTKRQE--------EYDEKLQTKENEIKR-L 588
++ E L V + + ++L L R E E K + K IK+ L
Sbjct: 1451 SMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQL 1510
Query: 589 VESMTEQEHVLNK-KEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVII 639
+ M E+E K E + LN K +E +++L KL+ + + +I
Sbjct: 1511 LSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLI 1562
Score = 57.6 bits (133), Expect = 1e-07
Identities = 126/694 (18%), Positives = 269/694 (38%), Gaps = 41/694 (5%)
Query: 3 QEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQV 62
+EEL + ++QTD + ++L E + ++H ++ ++ +E V+ ++++K L+D+ NQ
Sbjct: 559 EEELSVLKDQTDK-MKQEL-EAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQ- 615
Query: 63 MELYASLRNTHRK---MKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHS 119
+EL R+ H K + + ++ +E AKL Q Q + KA E
Sbjct: 616 LELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQ 675
Query: 120 TLDNKVTFDVNKLLNIPNS---LVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKI 176
+ KLL++ L + E ++K++ ++ I + L ++
Sbjct: 676 LAQLQ-----QKLLDLETERILLTKQVAEVEAQKKDVCTELDA-----HKIQVQDLMQQL 725
Query: 177 KEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRK--NANETMALQLRTKELSCALSDLNT 234
++ N+E + SL Q+ L++ N + ++ E M LQ+R + + L
Sbjct: 726 EKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKK-EIEILTQ 784
Query: 235 QNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVV 294
+ + IH + +N +K +L E +LK +E
Sbjct: 785 KLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTA 844
Query: 295 QLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLED-IALAR 353
LE + ++ + + LE + ++ + + L D I++
Sbjct: 845 -LELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWE 903
Query: 354 EKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKY----NDSIEEKKTL 409
+KL + + ++K ++ L + E+ K+ + +++ TL
Sbjct: 904 KKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTL 963
Query: 410 QENIDDLR------TDLLESELRVKDLVRELD-EKESILETKQCVQKELESTKTDLEHRK 462
E + L+ L + E ++K + +L+ + L+ +Q++L K E K
Sbjct: 964 NELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDK 1023
Query: 463 TEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRES 522
++ E L EE LKS S EK+ K + E+
Sbjct: 1024 RKVSELTSKLKTTDEEFQSLKS--SHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEA 1081
Query: 523 QMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKE 582
+++ EL+N+ + T ++ + + ++ L T E + +L+
Sbjct: 1082 LLEAKTNELINISSSKTN----AILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLT 1137
Query: 583 NEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLA 642
E L S + H L +KE +IK + E + L + + +A + +
Sbjct: 1138 EEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCIT 1197
Query: 643 KYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRTL 676
+ KK L+ + +++ LK + + + S+ L
Sbjct: 1198 QLKKELSENINAVTLMKEELKEKKVEISSLSKQL 1231
Score = 49.2 bits (112), Expect = 5e-05
Identities = 125/641 (19%), Positives = 248/641 (38%), Gaps = 56/641 (8%)
Query: 4 EELEIQQNQT---DGCLYEDLNEQESITSE-----SHKITKLKTV---WQEKMVTFEKSK 52
E+LE+ N++ + L E L E + + E S +KLKT +Q + EKS
Sbjct: 992 EKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSN 1051
Query: 53 KELEDRQNQVMELYASLRNTHRKMKLLGQKVN-LPSAEELHIMNVAKLSPEQLLQL---C 108
K LED+ + +L L ++ + +K L A+ ++N++ +L C
Sbjct: 1052 KSLEDKSLEFKKLSEELAI---QLDICCKKTEALLEAKTNELINISSSKTNAILSRISHC 1108
Query: 109 AGGEPKALEHSTLD----NKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQE 164
K E + +++ + +L N+L ++ + +E N +S+ +
Sbjct: 1109 QHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADI 1168
Query: 165 KGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKE 224
+ + T+ ++ + N + S + T+ KE+++ I+ + E ++
Sbjct: 1169 ESLVTEKEALQKEGGNQQQ--AASEKESCITQLKKELSENINAVTLMKEELKEKKVEISS 1226
Query: 225 LSCALSDLNTQ---NAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSR 281
LS L+DLN Q + + ++ + R + ++ K+++S
Sbjct: 1227 LSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISA 1286
Query: 282 AEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKD 341
E Q+ + + + + ++ + + + + D+++N L + +
Sbjct: 1287 LE-QVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQ 1345
Query: 342 NTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMN---LNIAKLIEIEKK 398
+ + E +S S I +++ + + I L E+ K
Sbjct: 1346 QNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKN 1405
Query: 399 YNDSIE-EKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTD 457
YN + E K L + + + E + RVK E +EK LE ++ S K +
Sbjct: 1406 YNQQKDIEHKELVQKLQHFQELGEEKDNRVK----EAEEKILTLEN------QVYSMKAE 1455
Query: 458 LEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXX 517
LE +K E+E + K EE+ L+ +L +E A K +
Sbjct: 1456 LETKKKELEHVNLSVKSKEEELKALEDRLESESAAK-LAELKRKAEQKIAAIKKQLLSQM 1514
Query: 518 XXRESQMKSYYEELMNLKNQITQLREFGAF---DNLNDVGN-----MINQQRDKLFELTK 569
+E Q K E ++ N Q RE + L V + +I + K
Sbjct: 1515 EEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYT 1574
Query: 570 RQEEYDEK---LQTKENEIKRLVESMTEQEHVLNK--KEKE 605
QEE D + +T E +I L ++TE+E +L + +EKE
Sbjct: 1575 EQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKE 1615
Score = 40.3 bits (90), Expect = 0.023
Identities = 91/509 (17%), Positives = 197/509 (38%), Gaps = 37/509 (7%)
Query: 5 ELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVME 64
++E + + E N+Q++ + + IT+LK E + K+EL++++ ++
Sbjct: 1167 DIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISS 1226
Query: 65 LYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNK 124
L L + + +++ ++L S +E I ++ K E+ +L + + + TL +
Sbjct: 1227 LSKQLTDLNVQLQ---NSISL-SEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKE 1282
Query: 125 VTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAEND 184
+ ++ + N + ++ + + N + L Q + + +K K ++ N
Sbjct: 1283 KISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLE-LKSKEAYEKDEQIN---- 1337
Query: 185 LLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIH 244
LLK LDQ F ++ D K + L+ K + + +L + +I
Sbjct: 1338 LLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIE 1397
Query: 245 SGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKD---RLSRAEHQLKTNVERVVQLEAALE 301
S + N+ + ++ R+ AE ++ T +V ++A LE
Sbjct: 1398 SLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELE 1457
Query: 302 QARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXX 361
+ E + +V + + E +K + IA +++L S
Sbjct: 1458 TKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAE--QKIAAIKKQLLSQME 1515
Query: 362 XXXXXXXXXSASY----NKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKK--------TL 409
+ S+ N +++ + E+++ KL +E ++++ + T
Sbjct: 1516 EKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTE 1575
Query: 410 QENIDDLRTDLLESELRVKDLVRELDEKESIL-----ETKQCVQKELE------STKTDL 458
QE D E ++ L R L EKE +L E ++ V E L
Sbjct: 1576 QEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKL 1635
Query: 459 EHRKTEIEEYKRLLFEKGEEIDELKSKLS 487
EH + + E + ++ EE++E K S
Sbjct: 1636 EHAEAKQHEDQSMIGHLQEELEEKNKKYS 1664
Score = 39.9 bits (89), Expect = 0.030
Identities = 59/375 (15%), Positives = 143/375 (38%), Gaps = 17/375 (4%)
Query: 275 MKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNK 334
M + L E ++ R+ Q+ E+ R + ER + ++ K
Sbjct: 228 MHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRK 287
Query: 335 LTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIE 394
L + + +E + E++ S + + L+ +L
Sbjct: 288 LKAEMDEQIKTIEKTS-EEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELAR 346
Query: 395 IEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKE--LE 452
E++ ++ ++ +E + ++ L +S+ + +E +++ES+ + +QK+ L
Sbjct: 347 KEQELTKKLQTRE--REFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILT 404
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXX 512
++ L + E E Y+ + E ++ KS E KD+
Sbjct: 405 ESENKLRDLQQEAETYRTRILELESSLE--KSLQENENQSKDLAVHLEAEKNKHNKEITV 462
Query: 513 XXXXXXXRESQMKS-----YYEELMNLKNQI-TQLREFGAFDNLNDVGNMINQQRDKLFE 566
+K + EEL LK Q T++ + + + + ++ +F+
Sbjct: 463 MVEKHKTELESLKHQQDALWAEELQVLKQQYQTEMEKLR--EKCEQEKETLLKDKEIIFQ 520
Query: 567 --LTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLH 624
+ + E+ EKL + E++ L ++E +K E+E+ +L ++ ++ +
Sbjct: 521 AHIEEMNEKTLEKLDVNQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKM 580
Query: 625 NKLELRNEADIDVII 639
++ + ++ +D II
Sbjct: 581 DEQKNHHQQQVDSII 595
Score = 32.7 bits (71), Expect = 4.6
Identities = 43/204 (21%), Positives = 89/204 (43%), Gaps = 13/204 (6%)
Query: 43 EKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPE 102
+++V +K + L Q +E+ + R+ K+ ++ +L E H + +L E
Sbjct: 1799 KEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDL---ELKHNSTLKQLMRE 1855
Query: 103 QLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKC-EETLFKRKEIINWFESLM 161
QL A + L+ + +NK + L++ EET K+I + L
Sbjct: 1856 FNTQL-------AQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLK 1908
Query: 162 SQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLR 221
K + L + +E A+ L++ L++L+ ++ +++ + N M LQ +
Sbjct: 1909 RTAKRYE-EILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVT-IMELQTQ 1966
Query: 222 TKELSCALSDLNTQNAEMRKQIHS 245
+ + +SD + E R+QIH+
Sbjct: 1967 LAQKTTLISDSKLKEQEFREQIHN 1990
Score = 31.9 bits (69), Expect = 8.0
Identities = 47/224 (20%), Positives = 99/224 (44%), Gaps = 8/224 (3%)
Query: 2 KQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQ 61
+QE+LE++ N T L + N Q + + ++T +T+ + + V E + E+ NQ
Sbjct: 1837 EQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEE-TNQ 1895
Query: 62 VMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPE-QLLQLCAGGEPKALEHST 120
+++ A + ++ +++ L + EE V L + + LQ + + E+
Sbjct: 1896 LLKKIAEKDDDLKRTAKRYEEI-LDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPG 1954
Query: 121 LDNKVTFDVNKLLNIPNSLV--DKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKE 178
DN ++ L +L+ K +E F R++I N + L EK + T+ K
Sbjct: 1955 NDNVTIMELQTQLAQKTTLISDSKLKEQEF-REQIHNLEDRLKKYEKNVYATTVGTPYKG 2013
Query: 179 FNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRT 222
N + + + E+L+++ + + + +TMA + T
Sbjct: 2014 GNLYHTDVSLFGEPTEFEYLRKV--LFEYMMGRETKTMAKVITT 2055
>L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated protein
protein.
Length = 1410
Score = 66.1 bits (154), Expect = 4e-10
Identities = 119/622 (19%), Positives = 265/622 (42%), Gaps = 48/622 (7%)
Query: 17 LYEDLNEQESITSE-SHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRK 75
++ +L+E+ T + ++++++T +Q F++ +++ E+++ ++L + + H K
Sbjct: 363 IHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSK 422
Query: 76 MKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNI 135
LL + L A + +LS E+L+ L+ S L+ ++ V +
Sbjct: 423 --LLETERQLGEAHG-RLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTEL 479
Query: 136 PNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRT 195
+ L DK ++ + ++ + + +E + + +I E + + L++ L + +
Sbjct: 480 QHQL-DKTKQQ-HQEQQALQQSTTAKLREAQNDLEQVLRQIGEKDQKIQNLEALLQKSKE 537
Query: 196 EFL---KEINDIIDCLRKNANETMAL-QLRTKE--LSCALSDL--NTQN-AEMRKQIHSG 246
KE D+ ++ ET L QL+ K L ++ L N +N +E KQ
Sbjct: 538 NISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQDEVTQLTENVKNQSESHKQAQEN 597
Query: 247 DHHRPY-------ANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAA 299
H + A ++ + K+++S+ + Q+K E ++ EAA
Sbjct: 598 LHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAA 657
Query: 300 LEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSX 359
R++ + +D QELNK+T + T L+D +++ S
Sbjct: 658 KTAQRAD-------LQNHLDTAQNALQDKHQELNKITTQLDQVTAKLQD----KQEHCSQ 706
Query: 360 XXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTD 419
S + ++++ ++ A +E++ ++++ LQ+ L TD
Sbjct: 707 LESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQD---LQQQ-RQLNTD 762
Query: 420 LLESELRVKDLVRELD-EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEE 478
L ELR +L ++L+ EKE + T+ +QK+ E+ ++ ++ + T+ EE K++L + E
Sbjct: 763 L---ELRATELSKQLEMEKEIVSSTRLDLQKKSEALES-IKQKLTKQEEEKQILKQDFET 818
Query: 479 IDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQI 538
+ + ++K+ E+ I ++ ++ + L N K++
Sbjct: 819 LSQ-ETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKD-KLSKVSDSLKNSKSEF 876
Query: 539 TQLREFG--AFDNLNDVGNMINQQRDKLFELT-KRQEEYDEKLQTKENEIKRLVESMTEQ 595
+ + G A +L + Q E T K Q+E + L+ ++ +L +
Sbjct: 877 EKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSM 936
Query: 596 EHVLNKKEKEIKMLNEKEEEHM 617
+ L + + +K NEKEE+ +
Sbjct: 937 QEQLIQAQNTLKQ-NEKEEQQL 957
Score = 55.2 bits (127), Expect = 8e-07
Identities = 123/620 (19%), Positives = 254/620 (40%), Gaps = 62/620 (10%)
Query: 49 EKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQL-LQL 107
E K+ E+ +QV E A LR ++ L VN +++ +N +K QL +Q+
Sbjct: 589 ESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQ----LNESKEKVSQLDIQI 644
Query: 108 CAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGI 167
A E + + N L N+L DK +E L K ++ + + Q+K
Sbjct: 645 KAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKHQE-LNKITTQLDQVTAKL-QDKQE 702
Query: 168 STKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSC 227
L +KE+ + L+ ++L + +K++ D L A++ ALQ ++
Sbjct: 703 HCSQLESHLKEYKEKYLSLEQKTEELEGQ-IKKLE--ADSLEVKASKEQALQDLQQQRQL 759
Query: 228 ALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLK 287
+DL + E+ KQ+ + +K +L++ E + +
Sbjct: 760 N-TDLELRATELSKQLEM--------EKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQ 810
Query: 288 TNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLE 347
+ E ++ + + L + + + + +L+ ++KD + +
Sbjct: 811 ILKQ---DFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELS-TVKDKLSKVS 866
Query: 348 DIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKK 407
D +L K S K+ K++KH++ + + ++ +K+ S+E++K
Sbjct: 867 D-SLKNSK--SEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEK 923
Query: 408 T----LQENIDDLRTDLLESELRVKDLVRELDEKE-SILETKQCVQ---KELESTKTDLE 459
L+ ++ ++ L++++ +K +E + + +I E KQ + K++E+ + +L+
Sbjct: 924 EASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELK 983
Query: 460 H---RKTEIE-EYKRLLFEKGEEIDELKSKLST-----EKAIKDIXXXXXXXXXXXXXXX 510
+KTE+E + ++ L + +E+ K K+S EK+ ++
Sbjct: 984 IAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKS-QETFKQLQSDFYGRESEL 1042
Query: 511 XXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDK----LFE 566
E ++ E+L++ +NQI + L + Q K L E
Sbjct: 1043 LATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKL--IQELKTAKATLEQDSAKKEQQLQE 1100
Query: 567 LTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEH-----MNIIN 621
K ++ ++ KE E+ + E E + ++EKEI LNE+ + H I N
Sbjct: 1101 RCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITN 1160
Query: 622 -------LLHNKLELRNEAD 634
L+ KLEL+ +AD
Sbjct: 1161 LKDAKQLLIQQKLELQGKAD 1180
Score = 52.8 bits (121), Expect = 4e-06
Identities = 117/632 (18%), Positives = 234/632 (37%), Gaps = 40/632 (6%)
Query: 23 EQESITSESHKITKLKTVWQEKMVT--FEKSKKELEDRQNQVMELYASLRNTHRKMKLLG 80
E +S+ ++ K L+ + Q++ + E EL + E+ +S R +K
Sbjct: 736 EADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEAL 795
Query: 81 QKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLV 140
+ + ++ + K E L Q E K ++H L+N++ V +L +
Sbjct: 796 ESIKQKLTKQEEEKQILKQDFETLSQ-----ETK-IQHEELNNRIQTTVTELQKVKMEKE 849
Query: 141 DKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDL--LKSSLDQLRTEFL 198
E + ++ +SL + + + K + E LK L L
Sbjct: 850 ALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTL 909
Query: 199 KEINDIIDCLRKNANETMALQLRTKELSCALSDL-NT--QNAEMRKQIHSGDHHRPYANR 255
KE ++ L K + L+L + L NT QN + +Q+ + ++
Sbjct: 910 KEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSE 969
Query: 256 NXXXXXXX-------XXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESW 308
+ ++ +L++A +L E++ L+ E+++
Sbjct: 970 QKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFK 1029
Query: 309 SLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXX 368
L+ +D KL+ + +D ++ I + +Q
Sbjct: 1030 QLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQ 1089
Query: 369 XXSASYN------KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQEN-IDDLRTDLL 421
+ K+++D++ E +L +L+ EK IEE K QE I L +L
Sbjct: 1090 DSAKKEQQLQERCKALQDIQKEKSLKEKELVN-EKSKLAEIEEIKCRQEKEITKLNEELK 1148
Query: 422 ESELR-VKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEID 480
+L +K++ D K+ +++ K +Q + +S K +E K + K + ++ EE+
Sbjct: 1149 SHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELK 1208
Query: 481 ----ELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXR-ESQMKSYYEELMNLK 535
E ++KL +E K++ + + +S + L+
Sbjct: 1209 KEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELE 1268
Query: 536 NQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQ 595
Q LR G L +R L E + E EKLQTK E++R +++ T
Sbjct: 1269 KQTDDLR--GEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKLDNTTAV 1326
Query: 596 EHVLNKKE----KEIKMLNEKEEEHMNIINLL 623
+ + + + K + LN K E + N +
Sbjct: 1327 QELGRENQSLQIKHTQALNRKWAEDNEVQNCM 1358
Score = 52.4 bits (120), Expect = 5e-06
Identities = 132/670 (19%), Positives = 259/670 (38%), Gaps = 70/670 (10%)
Query: 2 KQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQ 61
++ +L+ + L + E IT++ ++T QE E KE +++
Sbjct: 661 QRADLQNHLDTAQNALQDKHQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLS 720
Query: 62 VMELYASLRNTHRKMKLLGQKVNLPSAEELH-IMNVAKLSPEQLLQLCAGGEPKALE-HS 119
+ + L +K++ +V + L + +L+ + L+L A K LE
Sbjct: 721 LEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTD--LELRATELSKQLEMEK 778
Query: 120 TLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEF 179
+ + D+ K S+ K + +++ + FE+L SQE I + L +I+
Sbjct: 779 EIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETL-SQETKIQHEELNNRIQTT 837
Query: 180 NAENDLLKSSLDQLRTEF--LKE-INDIIDCLRKNANETMALQLRTKELSCALSDLNTQN 236
E +K + L TE +K+ ++ + D L+ + +E + ++ A+ DL
Sbjct: 838 VTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSE---FEKENQKGKAAILDLEKTC 894
Query: 237 AEMRKQIH---SGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERV 293
E++ Q+ + + M+++L +A++ LK N +
Sbjct: 895 KELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEE 954
Query: 294 VQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKL----TQSIKDNTTHLEDI 349
QL+ + + + S ++ + + NKL TQ+ ++ E I
Sbjct: 955 QQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKI 1014
Query: 350 ALAR---EKLQSXXXXXXXXXXXXSASYNKSIKDMKH-EMNLNIA--------------- 390
++ + EK Q + + +D+K E L++A
Sbjct: 1015 SVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQN 1074
Query: 391 KLIEIEKKYN-----DSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQ 445
KLI+ K DS ++++ LQE L+ E L+ K+LV E + I E K
Sbjct: 1075 KLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKC 1134
Query: 446 CVQKELESTKTDLEHRK-------TEIEEYKRLLFEKGEEI----DELKSKLSTEK---- 490
+KE+ +L+ K T +++ K+LL ++ E+ D LK+ + EK
Sbjct: 1135 RQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQ 1194
Query: 491 AIKD-IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDN 549
+KD + +E MK + E L QIT L E N
Sbjct: 1195 ILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNE-----N 1249
Query: 550 LNDVGNMINQQRDKLFELTKRQEE-------YDEKLQTKENEIKRLVESMTEQEHVLNKK 602
L V + ++ EL K+ ++ + +Q ++E + L+E + E + K
Sbjct: 1250 LGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKL 1309
Query: 603 EKEIKMLNEK 612
+ ++ L K
Sbjct: 1310 QTKVLELQRK 1319
Score = 50.8 bits (116), Expect = 2e-05
Identities = 155/737 (21%), Positives = 284/737 (38%), Gaps = 70/737 (9%)
Query: 1 MKQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQN 60
+K+E +++Q D E E E + ES K ++ + T + + EL
Sbjct: 226 LKKELVQVQ-TLMDNMTLERERESEKLKDESKKF---ESQYASSEATISQLRSELSKGPQ 281
Query: 61 QVMELYASLRNTHRKMKLLGQK-----VNLPSAEELHIMNVAKLSPEQLLQ--LCAGGEP 113
+V L+ + L QK NL E+ + K + E + + + A
Sbjct: 282 EVRVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQ 341
Query: 114 KALEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLT 173
K L+ L ++++ L I L +K E T K KE ++ E+ K K L
Sbjct: 342 KDLDCQQLQSRLSASETSLHRIHVELSEKGEATQ-KLKEELSEVETKYQHLKA-EFKQLQ 399
Query: 174 MKIKEFNAENDLLKSSLDQLRTEFL---KEINDIIDCLRK----NANETMALQLRTKELS 226
+ +E L+S ++QL ++ L +++ + L++ ++ + M + + +L
Sbjct: 400 QQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQ 459
Query: 227 CALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQL 286
LS L Q E H + D L + Q+
Sbjct: 460 LKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQND-LEQVLRQI 518
Query: 287 KTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQ---SIKDNT 343
+++ LEA L++++ E+ SL E LN+L + +++D
Sbjct: 519 GEKDQKIQNLEALLQKSK-ENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQDEV 577
Query: 344 THL--------EDIALAREKLQSXXXXXXXXXXXXS---ASYNKSIKDMKHEMNLNIAKL 392
T L E A+E L S S+ ++ ++N + K+
Sbjct: 578 TQLTENVKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKV 637
Query: 393 ----IEIEKKYND--SIEEKKT-----LQENIDDLRTDLLESELRVKDLVRELDEKESIL 441
I+I+ K S E KT LQ ++D + L + + + +LD+ + L
Sbjct: 638 SQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKHQELNKITTQLDQVTAKL 697
Query: 442 ETKQCVQKELESTKTDLEHRKTEIEEYKRLLFE--KGEEIDELKSKLSTEKAIKDIXXXX 499
+ KQ +LES + + + +E+ L K E D L+ K S E+A++D+
Sbjct: 698 QDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQR 757
Query: 500 XXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQ 559
+E + S +L + +++ + ++ Q
Sbjct: 758 QLNTDLELRATELSKQLEMEKEI-VSSTRLDLQKKSEALESIKQ--KLTKQEEEKQILKQ 814
Query: 560 QRDKLFELTKRQ-EEYDEKLQTKENEIKRL-VES---MTEQEHVLNKKEKEIKML-NEKE 613
+ L + TK Q EE + ++QT E++++ +E MTE V +K K L N K
Sbjct: 815 DFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKS 874
Query: 614 E-EHMN------IINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVLKCSL 666
E E N I++L EL+++ + + TL K +K L LEK ++ LK L
Sbjct: 875 EFEKENQKGKAAILDLEKTCKELKHQLQVQMENTL-KEQKELKKSLEKEKEASHQLKLEL 933
Query: 667 LGVVTQ----SRTLRKN 679
+ Q TL++N
Sbjct: 934 NSMQEQLIQAQNTLKQN 950
Score = 46.4 bits (105), Expect = 3e-04
Identities = 125/688 (18%), Positives = 280/688 (40%), Gaps = 55/688 (7%)
Query: 25 ESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVN 84
E + ++ +++T+ + E+ ++L+D + YAS T +++ +
Sbjct: 221 EDVAVLKKELVQVQTLMDNMTLERERESEKLKDESKKFESQYASSEATISQLR--SELSK 278
Query: 85 LPSAEELHIMNVAKL--SPEQLLQ----LCAGGEPKALEHSTLDNKVTFDVNKLLNIPNS 138
P +++ + KL S +L Q L K +++ L+ K + NI +
Sbjct: 279 GPQEVRVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQAT 338
Query: 139 LVDKCEETLFKRKEIINWFESLMSQEKGISTK-TLTMKIKEFNAENDLLKSSLDQLRTEF 197
L K + + + SL +S K T K+KE +E +++ L+ EF
Sbjct: 339 LHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSE---VETKYQHLKAEF 395
Query: 198 LKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNX 257
K++ ++ E LQL+++ ++ L+++ E +Q+ H R R
Sbjct: 396 -KQLQQ-----QREEKEQHGLQLQSE-----INQLHSKLLETERQLGEA-HGRLKEQRQL 443
Query: 258 XXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALE---QARSESWSLERTV 314
+ +LSR E QLK V +L+ L+ Q E +L+++
Sbjct: 444 SSEKLMDKEQQVADLQL---KLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQST 500
Query: 315 XXXXXXXXXXXEDFDQELNKLTQSIKDNTTHL----EDIALAREKLQSXXXXXXXXXXXX 370
E +++ + Q I++ L E+I+L EK +
Sbjct: 501 TAKLREAQNDLEQVLRQIGEKDQKIQNLEALLQKSKENISLL-EKEREDLYAKIQAGEGE 559
Query: 371 SASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEE-KKTLQENIDDLRTDLLESELRVKD 429
+A N+ +++ H + + +L E K ++S ++ ++ L + + + + L ++ RV
Sbjct: 560 TAVLNQ-LQEKNHTLQDEVTQLTENVKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLS 618
Query: 430 LVRELDEKESIL-ETKQCV-QKELE-STKTDL----EHRKT--------EIEEYKRLLFE 474
L ++E S L E+K+ V Q +++ KT+L E KT ++ + L +
Sbjct: 619 LETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQD 678
Query: 475 KGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNL 534
K +E++++ ++L A + +++ ++L
Sbjct: 679 KHQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEAD 738
Query: 535 KNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTE 594
++ +E A +L + + EL+K+ E E + + ++++ E++
Sbjct: 739 SLEVKASKE-QALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALES 797
Query: 595 QEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEK 654
+ L K+E+E ++L + E + H +L R + + + + K++ L+ E
Sbjct: 798 IKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEA--LMTEL 855
Query: 655 MSISNRVLKCSLLGVVTQSRTLRKNMSG 682
++ +++ K S ++S ++N G
Sbjct: 856 STVKDKLSKVSDSLKNSKSEFEKENQKG 883
Score = 37.1 bits (82), Expect = 0.21
Identities = 66/316 (20%), Positives = 135/316 (42%), Gaps = 29/316 (9%)
Query: 376 KSIKDMKHEMNLNIA-KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVREL 434
K +KD+ + +A ++ +I+ KY++ ++ ++ + L +L + ++DL EL
Sbjct: 155 KQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTEL 214
Query: 435 DEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEE-----------IDELK 483
++ I E ++KEL +T +++ E E L ++ ++ I +L+
Sbjct: 215 LQRPGI-EDVAVLKKELVQVQTLMDNMTLERERESEKLKDESKKFESQYASSEATISQLR 273
Query: 484 SKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSY--YEELMNLKN-QITQ 540
S+LS K +++ E+ +K Y +L N +
Sbjct: 274 SELS--KGPQEVRVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVS 331
Query: 541 LREFGAFDNLNDVGNMINQQRDKLFE--LTKRQEEYDEKLQTKENEIKRLVESMTEQEHV 598
+ A + D+ Q R E L + E EK + + + L E T+ +H
Sbjct: 332 KKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQH- 390
Query: 599 LNKKEKEIKMLNEKEEEH----MNIINLLHNKLELRNEADIDVIITLAKYKKSLT---LV 651
L + K+++ E++E+H + IN LH+KL L E + K ++ L+ L+
Sbjct: 391 LKAEFKQLQQQREEKEQHGLQLQSEINQLHSKL-LETERQLGEAHGRLKEQRQLSSEKLM 449
Query: 652 LEKMSISNRVLKCSLL 667
++ +++ LK S L
Sbjct: 450 DKEQQVADLQLKLSRL 465
>BC132784-1|AAI32785.1| 1116|Homo sapiens ELKS/RAB6-interacting/CAST
family member 1 protein.
Length = 1116
Score = 65.3 bits (152), Expect = 7e-10
Identities = 121/657 (18%), Positives = 255/657 (38%), Gaps = 58/657 (8%)
Query: 3 QEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQV 62
++++E+++++ L +N ++ S K + + +T K + + +NQ
Sbjct: 169 RKDVEVKESK----LSSSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQH 224
Query: 63 MEL-YASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTL 121
M++ +L++ R + L Q S+ VA+L+ E +L A E +A E
Sbjct: 225 MQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKE---- 280
Query: 122 DNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTL------TMK 175
F + K L ++ ++TL R E I ++ Q KG+S K T +
Sbjct: 281 ----LFLLRKTLEEMELRIETQKQTLNARDESIKKLLEML-QSKGLSAKATEEDHERTRR 335
Query: 176 IKEFNAENDLLKSSLDQ-------LRTEFLKEINDIIDCLRKNANETMALQLRTKELSCA 228
+ E L+S L+Q LR E + + D + A +T+ ++++ ++S
Sbjct: 336 LAEAEMHVHHLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTV-IEMKDSKISSM 394
Query: 229 LSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSI--MKDRLSRAEHQL 286
L E++ +G + +K+ LS E Q
Sbjct: 395 ERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQW 454
Query: 287 KTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHL 346
+ ++ L+A + Q + E + + F + + +K++ T
Sbjct: 455 EELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHI-EVLKESLTAK 513
Query: 347 EDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEI-------EKKY 399
E A + K I+DM E ++ ++ E+K
Sbjct: 514 EQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKV 573
Query: 400 NDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDE--------KESILETKQCVQKEL 451
N ++ + LQE + D + + RVK L + +E++ E ++ +++
Sbjct: 574 NVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLK 633
Query: 452 ESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA-IKDIXXXXXXXXXXXXXXX 510
E D ++ EI+ YK+ L + E++ L+ LS ++A + D+
Sbjct: 634 EQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKD 693
Query: 511 XXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKR 570
E ++ EE + +++Q+ + E A + + D++ L +
Sbjct: 694 SRLKTL----EIALEQKKEECLKMESQLKKAHE-AALE-----ARASPEMSDRIQHLERE 743
Query: 571 QEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEK-EEEHMNIINLLHNK 626
Y ++ + E+ RL+E + E E+ N K+K+I L + ++++ + NL H +
Sbjct: 744 ITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKE 800
Score = 48.8 bits (111), Expect = 7e-05
Identities = 106/514 (20%), Positives = 206/514 (40%), Gaps = 40/514 (7%)
Query: 1 MKQEELEIQQNQTDGCLYEDLNEQESITSE---SH------KITKLKTVWQEKMVTFEKS 51
++ E EIQ +++G L + E+E E SH K+ +LK K +E+
Sbjct: 398 LRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEEL 457
Query: 52 KKELEDRQNQVMELYASLRNTHRKMKLLGQKVNL------PSAEELHIMNVAKLSPEQLL 105
KK+ Q ++ ++ L ++ L K+ S + + ++ + + EQ
Sbjct: 458 KKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRA 517
Query: 106 QLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEK 165
+ E AL L+ K T +NK + D EE + EI + + L +E+
Sbjct: 518 AILQT-EVDALR-LRLEEKETM-LNKKTK---QIQDMAEEKGTQAGEIHDLKDMLDVKER 571
Query: 166 GISTKTLTMK-IKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKE 224
++ ++ ++E + + SSL + R + L+ D E +A + RT E
Sbjct: 572 KVNVLQKKIENLQEQLRDKEKQMSSLKE-RVKSLQADTTNTDTALTTLEEALAEKERTIE 630
Query: 225 LSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEH 284
D + + E +++I + + + S A
Sbjct: 631 RLKEQRDRDER--EKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASS 688
Query: 285 QLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXX-----EDFDQELNKLTQSI 339
LK + R+ LE ALEQ + E +E + D Q L +
Sbjct: 689 GLKKD-SRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRY 747
Query: 340 KDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEM-NLNIAKLIEIEKK 398
KD ++ + ++ A + +KD ++ NL + +E +KK
Sbjct: 748 KDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVE-KKK 806
Query: 399 YNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDE--KESILET--KQCVQKELEST 454
+EE + ++N++D L +S + D + EL+E +ES+ T ++ V + ES
Sbjct: 807 SAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESA 866
Query: 455 KTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLST 488
+T+ E ++EE + + +E++ +K+KLS+
Sbjct: 867 RTNAE---KQVEELLMAMEKVKQELESMKAKLSS 897
Score = 37.9 bits (84), Expect = 0.12
Identities = 85/500 (17%), Positives = 200/500 (40%), Gaps = 31/500 (6%)
Query: 3 QEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQV 62
+EEL ++ Q + + Q I ++++ T E + D + +
Sbjct: 444 KEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHI 503
Query: 63 MELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTL- 121
L SL ++ +L +V+ A L + + ++ Q+ E K + +
Sbjct: 504 EVLKESLTAKEQRAAILQTEVD---ALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIH 560
Query: 122 DNKVTFDVN-KLLNIPNSLVDKCEETLF-KRKEIINWFESLMS-QEKGISTKTLTMKIKE 178
D K DV + +N+ ++ +E L K K++ + E + S Q +T T ++E
Sbjct: 561 DLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEE 620
Query: 179 FNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAE 238
AE + L + R +E + ID +K+ + L+ + L LS+ +
Sbjct: 621 ALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKD---LKEKVSLLQGDLSEKEASLLD 677
Query: 239 MRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSI-MKDRLSRA-EHQLKTNV-----E 291
+++ H+ ++ + M+ +L +A E L+ +
Sbjct: 678 LKE--HASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSD 735
Query: 292 RVVQLEAALEQARSESWSLERTVXXXXXXXXXXXE---DFDQELNKLTQSIKDNTTHLED 348
R+ LE + + + ES + V D D+++ +L + +KD + +
Sbjct: 736 RIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVAN 795
Query: 349 IALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIE---E 405
+ + + + N S + ++ + ++ E+E+ +S++ E
Sbjct: 796 LKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAE 855
Query: 406 KKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEI 465
++ + + RT+ +E +V++L+ +++ + LE+ ++ +L ST+ L ++T +
Sbjct: 856 REMVLAQEESARTN---AEKQVEELLMAMEKVKQELES---MKAKLSSTQQSLAEKETHL 909
Query: 466 EEYKRLLFEKGEEIDELKSK 485
+ + EE+ E+K +
Sbjct: 910 TNLRAERRKHLEEVLEMKQE 929
Score = 36.7 bits (81), Expect = 0.28
Identities = 62/274 (22%), Positives = 122/274 (44%), Gaps = 28/274 (10%)
Query: 388 NIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKE---SIL--E 442
+I KL+E+ + S K +E+ + R L E+E+ V L L++KE S+L E
Sbjct: 308 SIKKLLEMLQSKGLSA---KATEEDHERTRR-LAEAEMHVHHLESLLEQKEKENSMLREE 363
Query: 443 TKQCVQKELESTKTD-----LEHRKTEIEEYKRLLFEKGEEIDELKSK--LSTEKAIKDI 495
+ + +S KT +E + ++I +R L + EEI LKS LSTE+ +++
Sbjct: 364 MHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEM 423
Query: 496 XXXXXXXXXXXXXXXXXXXXXX--XXRESQMKSYYEELMNLKNQITQLR-EFGAFDN--- 549
+E+Q + ++ L+ +I Q++ E D
Sbjct: 424 KQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELL 483
Query: 550 -----LNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEK 604
L + N + + + L + +++ + E+ L + E+E +LNKK K
Sbjct: 484 ALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTK 543
Query: 605 EIKMLNEKEEEHMNIINLLHNKLELRNEADIDVI 638
+I+ + E++ I+ L + L+++ E ++V+
Sbjct: 544 QIQDMAEEKGTQAGEIHDLKDMLDVK-ERKVNVL 576
>BC132782-1|AAI32783.1| 1116|Homo sapiens ELKS/RAB6-interacting/CAST
family member 1 protein.
Length = 1116
Score = 65.3 bits (152), Expect = 7e-10
Identities = 121/657 (18%), Positives = 255/657 (38%), Gaps = 58/657 (8%)
Query: 3 QEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQV 62
++++E+++++ L +N ++ S K + + +T K + + +NQ
Sbjct: 169 RKDVEVKESK----LSSSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQH 224
Query: 63 MEL-YASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTL 121
M++ +L++ R + L Q S+ VA+L+ E +L A E +A E
Sbjct: 225 MQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKE---- 280
Query: 122 DNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTL------TMK 175
F + K L ++ ++TL R E I ++ Q KG+S K T +
Sbjct: 281 ----LFLLRKTLEEMELRIETQKQTLNARDESIKKLLEML-QSKGLSAKATEEDHERTRR 335
Query: 176 IKEFNAENDLLKSSLDQ-------LRTEFLKEINDIIDCLRKNANETMALQLRTKELSCA 228
+ E L+S L+Q LR E + + D + A +T+ ++++ ++S
Sbjct: 336 LAEAEMHVHHLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTV-IEMKDSKISSM 394
Query: 229 LSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSI--MKDRLSRAEHQL 286
L E++ +G + +K+ LS E Q
Sbjct: 395 ERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQW 454
Query: 287 KTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHL 346
+ ++ L+A + Q + E + + F + + +K++ T
Sbjct: 455 EELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHI-EVLKESLTAK 513
Query: 347 EDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEI-------EKKY 399
E A + K I+DM E ++ ++ E+K
Sbjct: 514 EQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKV 573
Query: 400 NDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDE--------KESILETKQCVQKEL 451
N ++ + LQE + D + + RVK L + +E++ E ++ +++
Sbjct: 574 NVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLK 633
Query: 452 ESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA-IKDIXXXXXXXXXXXXXXX 510
E D ++ EI+ YK+ L + E++ L+ LS ++A + D+
Sbjct: 634 EQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKD 693
Query: 511 XXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKR 570
E ++ EE + +++Q+ + E A + + D++ L +
Sbjct: 694 SRLKTL----EIALEQKKEECLKMESQLKKAHE-AALE-----ARASPEMSDRIQHLERE 743
Query: 571 QEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEK-EEEHMNIINLLHNK 626
Y ++ + E+ RL+E + E E+ N K+K+I L + ++++ + NL H +
Sbjct: 744 ITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKE 800
Score = 48.8 bits (111), Expect = 7e-05
Identities = 106/514 (20%), Positives = 206/514 (40%), Gaps = 40/514 (7%)
Query: 1 MKQEELEIQQNQTDGCLYEDLNEQESITSE---SH------KITKLKTVWQEKMVTFEKS 51
++ E EIQ +++G L + E+E E SH K+ +LK K +E+
Sbjct: 398 LRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEEL 457
Query: 52 KKELEDRQNQVMELYASLRNTHRKMKLLGQKVNL------PSAEELHIMNVAKLSPEQLL 105
KK+ Q ++ ++ L ++ L K+ S + + ++ + + EQ
Sbjct: 458 KKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRA 517
Query: 106 QLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEK 165
+ E AL L+ K T +NK + D EE + EI + + L +E+
Sbjct: 518 AILQT-EVDALR-LRLEEKETM-LNKKTK---QIQDMAEEKGTQAGEIHDLKDMLDVKER 571
Query: 166 GISTKTLTMK-IKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKE 224
++ ++ ++E + + SSL + R + L+ D E +A + RT E
Sbjct: 572 KVNVLQKKIENLQEQLRDKEKQMSSLKE-RVKSLQADTTNTDTALTTLEEALAEKERTIE 630
Query: 225 LSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEH 284
D + + E +++I + + + S A
Sbjct: 631 RLKEQRDRDER--EKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASS 688
Query: 285 QLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXX-----EDFDQELNKLTQSI 339
LK + R+ LE ALEQ + E +E + D Q L +
Sbjct: 689 GLKKD-SRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRY 747
Query: 340 KDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEM-NLNIAKLIEIEKK 398
KD ++ + ++ A + +KD ++ NL + +E +KK
Sbjct: 748 KDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVE-KKK 806
Query: 399 YNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDE--KESILET--KQCVQKELEST 454
+EE + ++N++D L +S + D + EL+E +ES+ T ++ V + ES
Sbjct: 807 SAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESA 866
Query: 455 KTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLST 488
+T+ E ++EE + + +E++ +K+KLS+
Sbjct: 867 RTNAE---KQVEELLMAMEKVKQELESMKAKLSS 897
Score = 37.9 bits (84), Expect = 0.12
Identities = 85/500 (17%), Positives = 200/500 (40%), Gaps = 31/500 (6%)
Query: 3 QEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQV 62
+EEL ++ Q + + Q I ++++ T E + D + +
Sbjct: 444 KEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHI 503
Query: 63 MELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTL- 121
L SL ++ +L +V+ A L + + ++ Q+ E K + +
Sbjct: 504 EVLKESLTAKEQRAAILQTEVD---ALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIH 560
Query: 122 DNKVTFDVN-KLLNIPNSLVDKCEETLF-KRKEIINWFESLMS-QEKGISTKTLTMKIKE 178
D K DV + +N+ ++ +E L K K++ + E + S Q +T T ++E
Sbjct: 561 DLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEE 620
Query: 179 FNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAE 238
AE + L + R +E + ID +K+ + L+ + L LS+ +
Sbjct: 621 ALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKD---LKEKVSLLQGDLSEKEASLLD 677
Query: 239 MRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSI-MKDRLSRA-EHQLKTNV-----E 291
+++ H+ ++ + M+ +L +A E L+ +
Sbjct: 678 LKE--HASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSD 735
Query: 292 RVVQLEAALEQARSESWSLERTVXXXXXXXXXXXE---DFDQELNKLTQSIKDNTTHLED 348
R+ LE + + + ES + V D D+++ +L + +KD + +
Sbjct: 736 RIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVAN 795
Query: 349 IALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIE---E 405
+ + + + N S + ++ + ++ E+E+ +S++ E
Sbjct: 796 LKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAE 855
Query: 406 KKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEI 465
++ + + RT+ +E +V++L+ +++ + LE+ ++ +L ST+ L ++T +
Sbjct: 856 REMVLAQEESARTN---AEKQVEELLMAMEKVKQELES---MKAKLSSTQQSLAEKETHL 909
Query: 466 EEYKRLLFEKGEEIDELKSK 485
+ + EE+ E+K +
Sbjct: 910 TNLRAERRKHLEEVLEMKQE 929
Score = 36.7 bits (81), Expect = 0.28
Identities = 62/274 (22%), Positives = 122/274 (44%), Gaps = 28/274 (10%)
Query: 388 NIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKE---SIL--E 442
+I KL+E+ + S K +E+ + R L E+E+ V L L++KE S+L E
Sbjct: 308 SIKKLLEMLQSKGLSA---KATEEDHERTRR-LAEAEMHVHHLESLLEQKEKENSMLREE 363
Query: 443 TKQCVQKELESTKTD-----LEHRKTEIEEYKRLLFEKGEEIDELKSK--LSTEKAIKDI 495
+ + +S KT +E + ++I +R L + EEI LKS LSTE+ +++
Sbjct: 364 MHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEM 423
Query: 496 XXXXXXXXXXXXXXXXXXXXXX--XXRESQMKSYYEELMNLKNQITQLR-EFGAFDN--- 549
+E+Q + ++ L+ +I Q++ E D
Sbjct: 424 KQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELL 483
Query: 550 -----LNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEK 604
L + N + + + L + +++ + E+ L + E+E +LNKK K
Sbjct: 484 ALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTK 543
Query: 605 EIKMLNEKEEEHMNIINLLHNKLELRNEADIDVI 638
+I+ + E++ I+ L + L+++ E ++V+
Sbjct: 544 QIQDMAEEKGTQAGEIHDLKDMLDVK-ERKVNVL 576
>AB053471-1|BAC54110.1| 1116|Homo sapiens ELKS epsilon protein.
Length = 1116
Score = 65.3 bits (152), Expect = 7e-10
Identities = 121/657 (18%), Positives = 255/657 (38%), Gaps = 58/657 (8%)
Query: 3 QEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQV 62
++++E+++++ L +N ++ S K + + +T K + + +NQ
Sbjct: 169 RKDVEVKESK----LSSSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQH 224
Query: 63 MEL-YASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTL 121
M++ +L++ R + L Q S+ VA+L+ E +L A E +A E
Sbjct: 225 MQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKE---- 280
Query: 122 DNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTL------TMK 175
F + K L ++ ++TL R E I ++ Q KG+S K T +
Sbjct: 281 ----LFLLRKTLEEMELRIETQKQTLNARDESIKKLLEML-QSKGLSAKATEEDHERTRR 335
Query: 176 IKEFNAENDLLKSSLDQ-------LRTEFLKEINDIIDCLRKNANETMALQLRTKELSCA 228
+ E L+S L+Q LR E + + D + A +T+ ++++ ++S
Sbjct: 336 LAEAEMHVHHLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTV-IEMKDSKISSM 394
Query: 229 LSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSI--MKDRLSRAEHQL 286
L E++ +G + +K+ LS E Q
Sbjct: 395 ERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQW 454
Query: 287 KTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHL 346
+ ++ L+A + Q + E + + F + + +K++ T
Sbjct: 455 EELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHI-EVLKESLTAK 513
Query: 347 EDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEI-------EKKY 399
E A + K I+DM E ++ ++ E+K
Sbjct: 514 EQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKV 573
Query: 400 NDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDE--------KESILETKQCVQKEL 451
N ++ + LQE + D + + RVK L + +E++ E ++ +++
Sbjct: 574 NVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLK 633
Query: 452 ESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA-IKDIXXXXXXXXXXXXXXX 510
E D ++ EI+ YK+ L + E++ L+ LS ++A + D+
Sbjct: 634 EQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKD 693
Query: 511 XXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKR 570
E ++ EE + +++Q+ + E A + + D++ L +
Sbjct: 694 SRLKTL----EIALEQKKEECLKMESQLKKAHE-AALE-----ARASPEMSDRIQHLERE 743
Query: 571 QEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEK-EEEHMNIINLLHNK 626
Y ++ + E+ RL+E + E E+ N K+K+I L + ++++ + NL H +
Sbjct: 744 ITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKE 800
Score = 48.8 bits (111), Expect = 7e-05
Identities = 106/514 (20%), Positives = 206/514 (40%), Gaps = 40/514 (7%)
Query: 1 MKQEELEIQQNQTDGCLYEDLNEQESITSE---SH------KITKLKTVWQEKMVTFEKS 51
++ E EIQ +++G L + E+E E SH K+ +LK K +E+
Sbjct: 398 LRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEEL 457
Query: 52 KKELEDRQNQVMELYASLRNTHRKMKLLGQKVNL------PSAEELHIMNVAKLSPEQLL 105
KK+ Q ++ ++ L ++ L K+ S + + ++ + + EQ
Sbjct: 458 KKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRA 517
Query: 106 QLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEK 165
+ E AL L+ K T +NK + D EE + EI + + L +E+
Sbjct: 518 AILQT-EVDALR-LRLEEKETM-LNKKTK---QIQDMAEEKGTQAGEIHDLKDMLDVKER 571
Query: 166 GISTKTLTMK-IKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKE 224
++ ++ ++E + + SSL + R + L+ D E +A + RT E
Sbjct: 572 KVNVLQKKIENLQEQLRDKEKQMSSLKE-RVKSLQADTTNTDTALTTLEEALAEKERTIE 630
Query: 225 LSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEH 284
D + + E +++I + + + S A
Sbjct: 631 RLKEQRDRDER--EKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASS 688
Query: 285 QLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXX-----EDFDQELNKLTQSI 339
LK + R+ LE ALEQ + E +E + D Q L +
Sbjct: 689 GLKKD-SRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRY 747
Query: 340 KDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEM-NLNIAKLIEIEKK 398
KD ++ + ++ A + +KD ++ NL + +E +KK
Sbjct: 748 KDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVE-KKK 806
Query: 399 YNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDE--KESILET--KQCVQKELEST 454
+EE + ++N++D L +S + D + EL+E +ES+ T ++ V + ES
Sbjct: 807 SAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESA 866
Query: 455 KTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLST 488
+T+ E ++EE + + +E++ +K+KLS+
Sbjct: 867 RTNAE---KQVEELLMAMEKVKQELESMKAKLSS 897
Score = 37.9 bits (84), Expect = 0.12
Identities = 85/500 (17%), Positives = 200/500 (40%), Gaps = 31/500 (6%)
Query: 3 QEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQV 62
+EEL ++ Q + + Q I ++++ T E + D + +
Sbjct: 444 KEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHI 503
Query: 63 MELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTL- 121
L SL ++ +L +V+ A L + + ++ Q+ E K + +
Sbjct: 504 EVLKESLTAKEQRAAILQTEVD---ALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIH 560
Query: 122 DNKVTFDVN-KLLNIPNSLVDKCEETLF-KRKEIINWFESLMS-QEKGISTKTLTMKIKE 178
D K DV + +N+ ++ +E L K K++ + E + S Q +T T ++E
Sbjct: 561 DLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEE 620
Query: 179 FNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAE 238
AE + L + R +E + ID +K+ + L+ + L LS+ +
Sbjct: 621 ALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKD---LKEKVSLLQGDLSEKEASLLD 677
Query: 239 MRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSI-MKDRLSRA-EHQLKTNV-----E 291
+++ H+ ++ + M+ +L +A E L+ +
Sbjct: 678 LKE--HASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSD 735
Query: 292 RVVQLEAALEQARSESWSLERTVXXXXXXXXXXXE---DFDQELNKLTQSIKDNTTHLED 348
R+ LE + + + ES + V D D+++ +L + +KD + +
Sbjct: 736 RIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVAN 795
Query: 349 IALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIE---E 405
+ + + + N S + ++ + ++ E+E+ +S++ E
Sbjct: 796 LKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAE 855
Query: 406 KKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEI 465
++ + + RT+ +E +V++L+ +++ + LE+ ++ +L ST+ L ++T +
Sbjct: 856 REMVLAQEESARTN---AEKQVEELLMAMEKVKQELES---MKAKLSSTQQSLAEKETHL 909
Query: 466 EEYKRLLFEKGEEIDELKSK 485
+ + EE+ E+K +
Sbjct: 910 TNLRAERRKHLEEVLEMKQE 929
Score = 36.7 bits (81), Expect = 0.28
Identities = 62/274 (22%), Positives = 122/274 (44%), Gaps = 28/274 (10%)
Query: 388 NIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKE---SIL--E 442
+I KL+E+ + S K +E+ + R L E+E+ V L L++KE S+L E
Sbjct: 308 SIKKLLEMLQSKGLSA---KATEEDHERTRR-LAEAEMHVHHLESLLEQKEKENSMLREE 363
Query: 443 TKQCVQKELESTKTD-----LEHRKTEIEEYKRLLFEKGEEIDELKSK--LSTEKAIKDI 495
+ + +S KT +E + ++I +R L + EEI LKS LSTE+ +++
Sbjct: 364 MHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEM 423
Query: 496 XXXXXXXXXXXXXXXXXXXXXX--XXRESQMKSYYEELMNLKNQITQLR-EFGAFDN--- 549
+E+Q + ++ L+ +I Q++ E D
Sbjct: 424 KQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELL 483
Query: 550 -----LNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEK 604
L + N + + + L + +++ + E+ L + E+E +LNKK K
Sbjct: 484 ALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTK 543
Query: 605 EIKMLNEKEEEHMNIINLLHNKLELRNEADIDVI 638
+I+ + E++ I+ L + L+++ E ++V+
Sbjct: 544 QIQDMAEEKGTQAGEIHDLKDMLDVK-ERKVNVL 576
>M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein.
Length = 1976
Score = 62.1 bits (144), Expect = 7e-09
Identities = 120/607 (19%), Positives = 236/607 (38%), Gaps = 52/607 (8%)
Query: 17 LYEDLNEQESITSESHKITKLKTVWQEKMVT-FEKSKKELEDRQNQVMELYASLRNTHRK 75
L E L++ ES E + ++ ++KM + +++L++ + +L K
Sbjct: 920 LEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAK 979
Query: 76 MKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNI 135
+K + +++ L + + KL +++ + C+ A E N + K+ N
Sbjct: 980 IKKMEEEILLLEDQNSKFIKEKKLMEDRIAE-CSS--QLAEEEEKAKN-----LAKIRNK 1031
Query: 136 PNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRT 195
++ EE L K ++ E + G T L +I E A+ +D+L+
Sbjct: 1032 QEVMISDLEERLKKEEKTRQELEKAKRKLDG-ETTDLQDQIAELQAQ-------IDELKL 1083
Query: 196 EFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANR 255
+ K+ ++ L + +ET+ K + +L Q AE+++ S R A +
Sbjct: 1084 QLAKKEEELQGALARGDDETLHKNNALK----VVRELQAQIAELQEDFESEKASRNKAEK 1139
Query: 256 NXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVER-VVQLEAALEQARSESWSLERTV 314
+ + A+ +L+T E+ V +L+ ALE+ E+ + E +
Sbjct: 1140 QKRDLSEELEALKTELEDTLDT--TAAQQELRTKREQEVAELKKALEE---ETKNHEAQI 1194
Query: 315 XXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASY 374
E+ ++L + + K N + K + S
Sbjct: 1195 QDMRQRHATALEELSEQLEQ-AKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHK 1253
Query: 375 NKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVREL 434
K + E++ AK+ E ++ + E+ LQ +D++ T L E+E + ++
Sbjct: 1254 RKKLDAQVQELH---AKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDA 1310
Query: 435 DEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE-----------LK 483
ES L+ Q + +E K +L R ++EE K L E+ EE +E L+
Sbjct: 1311 ASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQ 1370
Query: 484 SKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLRE 543
S+L+ K D R + Y++L KN++ Q
Sbjct: 1371 SQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQ--- 1427
Query: 544 FGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKE 603
L+D+ ++ QR L K+Q+++D+ L +++ R E E +E
Sbjct: 1428 -----ELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAE--AEARE 1480
Query: 604 KEIKMLN 610
KE K L+
Sbjct: 1481 KETKALS 1487
Score = 46.0 bits (104), Expect = 5e-04
Identities = 59/300 (19%), Positives = 129/300 (43%), Gaps = 19/300 (6%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD 435
K++ ++++ + I+ L E KK + +E + + +D TDL + ++ +L ++D
Sbjct: 1023 KNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQD---QIAELQAQID 1079
Query: 436 E-KESILETKQCVQKELESTKTDLEHRKTEIEEYKRL---LFEKGEEIDELK-SKLSTEK 490
E K + + ++ +Q L + H+ ++ + L + E E+ + K S+ EK
Sbjct: 1080 ELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEK 1139
Query: 491 AIKDIXXXXXXXXXXXXXXXXXXXXXX---XXRESQM----KSYYEELMNLKNQITQLRE 543
+D+ RE ++ K+ EE N + QI +R+
Sbjct: 1140 QKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQ 1199
Query: 544 FGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKE 603
A L ++ + Q + L K ++ + + E+K L + E EH K +
Sbjct: 1200 RHA-TALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLD 1258
Query: 604 KEIKMLNEKEEEHMNI-INLLHNKLELRNEAD-IDVIITLAKYKKSLTLVLEKMSISNRV 661
+++ L+ K E + + L +L+NE D + ++ A+ KK + + S+ +++
Sbjct: 1259 AQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAE-KKGIKFAKDAASLESQL 1317
Score = 41.5 bits (93), Expect = 0.010
Identities = 47/226 (20%), Positives = 93/226 (41%), Gaps = 9/226 (3%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKE 450
+L E+E+K+ +EEK L E + E+E L + E E IL + +E
Sbjct: 874 ELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEE 933
Query: 451 LESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXX 510
E L++ K +++ + + L E+ +E + + KL EK +
Sbjct: 934 EEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEK----VTAEAKIKKMEEEILL 989
Query: 511 XXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKR 570
+E ++ + + +Q+ + E NL + N L E K+
Sbjct: 990 LEDQNSKFIKEKKLME--DRIAECSSQLAEEEE--KAKNLAKIRNKQEVMISDLEERLKK 1045
Query: 571 QEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM-LNEKEEE 615
+E+ ++L+ + ++ + +Q L + E+K+ L +KEEE
Sbjct: 1046 EEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEE 1091
Score = 38.7 bits (86), Expect = 0.070
Identities = 101/527 (19%), Positives = 215/527 (40%), Gaps = 49/527 (9%)
Query: 6 LEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMEL 65
LE Q T L E+ ++ +++S ++ + K QE+ E+++K LE QV+ L
Sbjct: 1313 LESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLE---KQVLAL 1369
Query: 66 YASLRNTHRKMKL-LGQKVNLPSAEELHIMNVAKLSP---EQLLQLCAGGEPKALEHSTL 121
+ L +T +K+ LG +L A++ + + LS E+ L + K L
Sbjct: 1370 QSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQEL 1429
Query: 122 DNKVTFDVNKLLNIPNSLVDK---CEETLFKRKEIINWFES------LMSQEKGISTKTL 172
D+ +T D++ + ++L K ++ L + K I + ++EK +L
Sbjct: 1430 DD-LTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSL 1488
Query: 173 TMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANET----MALQLRTKELSCA 228
++E + + QLR + ++++ D + KN +E AL+ + +E+
Sbjct: 1489 ARALEEALEAKEEFERQNKQLRAD-MEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQ 1547
Query: 229 LSDLN-----TQNAEMRKQIH----SGDHHRPYANR---NXXXXXXXXXXXXXXXXSIMK 276
L +L T++A++R +++ R R N +
Sbjct: 1548 LEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELED 1607
Query: 277 DRLSRA-----EHQLKTNVERV-VQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQ 330
+R RA + +++ +++ + Q+EAA +AR E R + E+
Sbjct: 1608 ERKQRALAVASKKKMEIDLKDLEAQIEAA-NKARDEVIKQLRKLQAQMKDYQRELEEARA 1666
Query: 331 ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIA 390
+++ K++ L+ + +LQ ++ ++ + + A
Sbjct: 1667 SRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSA 1726
Query: 391 KLIE---IEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCV 447
L E +E + EE + Q N++ L ++ L+V L EL + S +
Sbjct: 1727 LLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNA 1786
Query: 448 QKELESTKTDLEHRKTEIE-----EYKRLLFEKGEEIDELKSKLSTE 489
+++LE +L+ + E+E ++K + +I +L+ +L E
Sbjct: 1787 RQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQE 1833
Score = 37.9 bits (84), Expect = 0.12
Identities = 44/182 (24%), Positives = 84/182 (46%), Gaps = 24/182 (13%)
Query: 326 EDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEM 385
E ++ KL + + + LE+ ALA +KL+ + D+ H+
Sbjct: 1388 ESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTV-------DLDHQR 1440
Query: 386 NLNIAKLIEIEKKYNDSIEEKKTLQ----ENIDDLRTDLLESELRVKDLVRELDE----K 437
+ + L + +KK++ + E+K++ E D + E E + L R L+E K
Sbjct: 1441 QV-ASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAK 1499
Query: 438 ESILETKQCVQKELE---STKTDLEHRKTEIEEYKRLLFEKGEE----IDELKSKL-STE 489
E + ++ ++E S+K D+ E+E+ KR L ++ EE ++EL+ +L +TE
Sbjct: 1500 EEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATE 1559
Query: 490 KA 491
A
Sbjct: 1560 DA 1561
Score = 35.9 bits (79), Expect = 0.49
Identities = 55/318 (17%), Positives = 123/318 (38%), Gaps = 17/318 (5%)
Query: 167 ISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELS 226
I K L +I+ N D + L +L+ + +K+ ++ R + +E A ++KE
Sbjct: 1624 IDLKDLEAQIEAANKARDEVIKQLRKLQAQ-MKDYQRELEEARASRDEIFA---QSKESE 1679
Query: 227 CALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIM--KDRLSRAEH 284
L L + ++++++ S + R +A + +++ K RL
Sbjct: 1680 KKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIA 1739
Query: 285 QLKTNVERVVQ-LEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNT 343
QL+ +E +E ++ R + ++ T+ + D +L + K+
Sbjct: 1740 QLEEELEEEQSNMELLNDRFRKTTLQVD-TLNAELAAERSAAQKSDNARQQLERQNKELK 1798
Query: 344 THLEDIALA-REKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDS 402
L+++ A + K ++ + K+ L + EKK +
Sbjct: 1799 AKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKL----VRRTEKKLKEI 1854
Query: 403 IEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKES----ILETKQCVQKELESTKTDL 458
+ + + + D + + ++ R+K L R+L+E E +++ +Q+EL+
Sbjct: 1855 FMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEAN 1914
Query: 459 EHRKTEIEEYKRLLFEKG 476
E E+ K L G
Sbjct: 1915 EGLSREVSTLKNRLRRGG 1932
Score = 34.7 bits (76), Expect = 1.1
Identities = 55/284 (19%), Positives = 121/284 (42%), Gaps = 30/284 (10%)
Query: 374 YNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRE 433
+ + K ++ +M ++ ++ K ++ + K+ L++ ++++RT L E E +L
Sbjct: 1502 FERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELE---DELQAT 1558
Query: 434 LDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI-----DELKSK--- 485
D K + Q ++ + E DL+ R + EE KRLL ++ E+ DE K +
Sbjct: 1559 EDAKLRLEVNMQAMKAQFER---DLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALA 1615
Query: 486 LSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQL--RE 543
++++K ++ ++QMK Y EL + ++ +
Sbjct: 1616 VASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQS 1675
Query: 544 FGAFDNLNDVGNMINQQRDKLF--ELTKR--QEEYDEKLQTKEN----------EIKRLV 589
+ L + I Q +++L E +R ++E DE N E +RL
Sbjct: 1676 KESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLE 1735
Query: 590 ESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEA 633
+ + E L +++ +++LN++ + ++ L+ +L A
Sbjct: 1736 ARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSA 1779
Score = 33.1 bits (72), Expect = 3.5
Identities = 64/334 (19%), Positives = 130/334 (38%), Gaps = 25/334 (7%)
Query: 172 LTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNAN-----ETMALQLRTK--E 224
L +K K+ E +L +++ + L+E N + + L+ E M +L K E
Sbjct: 862 LKVKEKQTKVEGEL--EEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQE 919
Query: 225 LSCALSDLNT--QNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRA 282
L L DL + + E R QI + + A+ + K A
Sbjct: 920 LEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEK---VTA 976
Query: 283 EHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDN 342
E ++K E ++ LE + E +E + E+ + L K+ +
Sbjct: 977 EAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEE-EEKAKNLAKIRNKQEVM 1035
Query: 343 TTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDS 402
+ LE+ EK + + I +++ +++ +L + E++ +
Sbjct: 1036 ISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGA 1095
Query: 403 IE--EKKTLQEN-----IDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTK 455
+ + +TL +N + +L+ + E + +D E + + K+ + +ELE+ K
Sbjct: 1096 LARGDDETLHKNNALKVVRELQAQIAELQ---EDFESEKASRNKAEKQKRDLSEELEALK 1152
Query: 456 TDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
T+LE + L ++ +E+ ELK L E
Sbjct: 1153 TELEDTLDTTAAQQELRTKREQEVAELKKALEEE 1186
>BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,
non-muscle protein.
Length = 1976
Score = 62.1 bits (144), Expect = 7e-09
Identities = 120/607 (19%), Positives = 236/607 (38%), Gaps = 52/607 (8%)
Query: 17 LYEDLNEQESITSESHKITKLKTVWQEKMVT-FEKSKKELEDRQNQVMELYASLRNTHRK 75
L E L++ ES E + ++ ++KM + +++L++ + +L K
Sbjct: 920 LEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAK 979
Query: 76 MKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNI 135
+K + +++ L + + KL +++ + C+ A E N + K+ N
Sbjct: 980 IKKMEEEILLLEDQNSKFIKEKKLMEDRIAE-CSS--QLAEEEEKAKN-----LAKIRNK 1031
Query: 136 PNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRT 195
++ EE L K ++ E + G T L +I E A+ +D+L+
Sbjct: 1032 QEVMISDLEERLKKEEKTRQELEKAKRKLDG-ETTDLQDQIAELQAQ-------IDELKL 1083
Query: 196 EFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANR 255
+ K+ ++ L + +ET+ K + +L Q AE+++ S R A +
Sbjct: 1084 QLAKKEEELQGALARGDDETLHKNNALK----VVRELQAQIAELQEDFESEKASRNKAEK 1139
Query: 256 NXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVER-VVQLEAALEQARSESWSLERTV 314
+ + A+ +L+T E+ V +L+ ALE+ E+ + E +
Sbjct: 1140 QKRDLSEELEALKTELEDTLDT--TAAQQELRTKREQEVAELKKALEE---ETKNHEAQI 1194
Query: 315 XXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASY 374
E+ ++L + + K N + K + S
Sbjct: 1195 QDMRQRHATALEELSEQLEQ-AKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHK 1253
Query: 375 NKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVREL 434
K + E++ AK+ E ++ + E+ LQ +D++ T L E+E + ++
Sbjct: 1254 RKKLDAQVQELH---AKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDA 1310
Query: 435 DEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE-----------LK 483
ES L+ Q + +E K +L R ++EE K L E+ EE +E L+
Sbjct: 1311 ASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQ 1370
Query: 484 SKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLRE 543
S+L+ K D R + Y++L KN++ Q
Sbjct: 1371 SQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQ--- 1427
Query: 544 FGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKE 603
L+D+ ++ QR L K+Q+++D+ L +++ R E E +E
Sbjct: 1428 -----ELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAE--AEARE 1480
Query: 604 KEIKMLN 610
KE K L+
Sbjct: 1481 KETKALS 1487
Score = 46.0 bits (104), Expect = 5e-04
Identities = 59/300 (19%), Positives = 129/300 (43%), Gaps = 19/300 (6%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD 435
K++ ++++ + I+ L E KK + +E + + +D TDL + ++ +L ++D
Sbjct: 1023 KNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQD---QIAELQAQID 1079
Query: 436 E-KESILETKQCVQKELESTKTDLEHRKTEIEEYKRL---LFEKGEEIDELK-SKLSTEK 490
E K + + ++ +Q L + H+ ++ + L + E E+ + K S+ EK
Sbjct: 1080 ELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEK 1139
Query: 491 AIKDIXXXXXXXXXXXXXXXXXXXXXX---XXRESQM----KSYYEELMNLKNQITQLRE 543
+D+ RE ++ K+ EE N + QI +R+
Sbjct: 1140 QKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQ 1199
Query: 544 FGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKE 603
A L ++ + Q + L K ++ + + E+K L + E EH K +
Sbjct: 1200 RHA-TALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLD 1258
Query: 604 KEIKMLNEKEEEHMNI-INLLHNKLELRNEAD-IDVIITLAKYKKSLTLVLEKMSISNRV 661
+++ L+ K E + + L +L+NE D + ++ A+ KK + + S+ +++
Sbjct: 1259 AQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAE-KKGIKFAKDAASLESQL 1317
Score = 41.5 bits (93), Expect = 0.010
Identities = 47/226 (20%), Positives = 93/226 (41%), Gaps = 9/226 (3%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKE 450
+L E+E+K+ +EEK L E + E+E L + E E IL + +E
Sbjct: 874 ELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEE 933
Query: 451 LESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXX 510
E L++ K +++ + + L E+ +E + + KL EK +
Sbjct: 934 EEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEK----VTAEAKIKKMEEEILL 989
Query: 511 XXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKR 570
+E ++ + + +Q+ + E NL + N L E K+
Sbjct: 990 LEDQNSKFIKEKKLME--DRIAECSSQLAEEEE--KAKNLAKIRNKQEVMISDLEERLKK 1045
Query: 571 QEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM-LNEKEEE 615
+E+ ++L+ + ++ + +Q L + E+K+ L +KEEE
Sbjct: 1046 EEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEE 1091
Score = 38.7 bits (86), Expect = 0.070
Identities = 101/527 (19%), Positives = 215/527 (40%), Gaps = 49/527 (9%)
Query: 6 LEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMEL 65
LE Q T L E+ ++ +++S ++ + K QE+ E+++K LE QV+ L
Sbjct: 1313 LESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLE---KQVLAL 1369
Query: 66 YASLRNTHRKMKL-LGQKVNLPSAEELHIMNVAKLSP---EQLLQLCAGGEPKALEHSTL 121
+ L +T +K+ LG +L A++ + + LS E+ L + K L
Sbjct: 1370 QSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQEL 1429
Query: 122 DNKVTFDVNKLLNIPNSLVDK---CEETLFKRKEIINWFES------LMSQEKGISTKTL 172
D+ +T D++ + ++L K ++ L + K I + ++EK +L
Sbjct: 1430 DD-LTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSL 1488
Query: 173 TMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANET----MALQLRTKELSCA 228
++E + + QLR + ++++ D + KN +E AL+ + +E+
Sbjct: 1489 ARALEEALEAKEEFERQNKQLRAD-MEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQ 1547
Query: 229 LSDLN-----TQNAEMRKQIH----SGDHHRPYANR---NXXXXXXXXXXXXXXXXSIMK 276
L +L T++A++R +++ R R N +
Sbjct: 1548 LEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELED 1607
Query: 277 DRLSRA-----EHQLKTNVERV-VQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQ 330
+R RA + +++ +++ + Q+EAA +AR E R + E+
Sbjct: 1608 ERKQRALAVASKKKMEIDLKDLEAQIEAA-NKARDEVIKQLRKLQAQMKDYQRELEEARA 1666
Query: 331 ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIA 390
+++ K++ L+ + +LQ ++ ++ + + A
Sbjct: 1667 SRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSA 1726
Query: 391 KLIE---IEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCV 447
L E +E + EE + Q N++ L ++ L+V L EL + S +
Sbjct: 1727 LLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNA 1786
Query: 448 QKELESTKTDLEHRKTEIE-----EYKRLLFEKGEEIDELKSKLSTE 489
+++LE +L+ + E+E ++K + +I +L+ +L E
Sbjct: 1787 RQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQE 1833
Score = 37.9 bits (84), Expect = 0.12
Identities = 44/182 (24%), Positives = 84/182 (46%), Gaps = 24/182 (13%)
Query: 326 EDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEM 385
E ++ KL + + + LE+ ALA +KL+ + D+ H+
Sbjct: 1388 ESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTV-------DLDHQR 1440
Query: 386 NLNIAKLIEIEKKYNDSIEEKKTLQ----ENIDDLRTDLLESELRVKDLVRELDE----K 437
+ + L + +KK++ + E+K++ E D + E E + L R L+E K
Sbjct: 1441 QV-ASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAK 1499
Query: 438 ESILETKQCVQKELE---STKTDLEHRKTEIEEYKRLLFEKGEE----IDELKSKL-STE 489
E + ++ ++E S+K D+ E+E+ KR L ++ EE ++EL+ +L +TE
Sbjct: 1500 EEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATE 1559
Query: 490 KA 491
A
Sbjct: 1560 DA 1561
Score = 35.9 bits (79), Expect = 0.49
Identities = 55/318 (17%), Positives = 123/318 (38%), Gaps = 17/318 (5%)
Query: 167 ISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELS 226
I K L +I+ N D + L +L+ + +K+ ++ R + +E A ++KE
Sbjct: 1624 IDLKDLEAQIEAANKARDEVIKQLRKLQAQ-MKDYQRELEEARASRDEIFA---QSKESE 1679
Query: 227 CALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIM--KDRLSRAEH 284
L L + ++++++ S + R +A + +++ K RL
Sbjct: 1680 KKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIA 1739
Query: 285 QLKTNVERVVQ-LEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNT 343
QL+ +E +E ++ R + ++ T+ + D +L + K+
Sbjct: 1740 QLEEELEEEQSNMELLNDRFRKTTLQVD-TLNAELAAERSAAQKSDNARQQLERQNKELK 1798
Query: 344 THLEDIALA-REKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDS 402
L+++ A + K ++ + K+ L + EKK +
Sbjct: 1799 AKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKL----VRRTEKKLKEI 1854
Query: 403 IEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKES----ILETKQCVQKELESTKTDL 458
+ + + + D + + ++ R+K L R+L+E E +++ +Q+EL+
Sbjct: 1855 FMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEAN 1914
Query: 459 EHRKTEIEEYKRLLFEKG 476
E E+ K L G
Sbjct: 1915 EGLSREVSTLKNRLRRGG 1932
Score = 34.7 bits (76), Expect = 1.1
Identities = 55/284 (19%), Positives = 121/284 (42%), Gaps = 30/284 (10%)
Query: 374 YNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRE 433
+ + K ++ +M ++ ++ K ++ + K+ L++ ++++RT L E E +L
Sbjct: 1502 FERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELE---DELQAT 1558
Query: 434 LDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI-----DELKSK--- 485
D K + Q ++ + E DL+ R + EE KRLL ++ E+ DE K +
Sbjct: 1559 EDAKLRLEVNMQAMKAQFER---DLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALA 1615
Query: 486 LSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQL--RE 543
++++K ++ ++QMK Y EL + ++ +
Sbjct: 1616 VASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQS 1675
Query: 544 FGAFDNLNDVGNMINQQRDKLF--ELTKR--QEEYDEKLQTKEN----------EIKRLV 589
+ L + I Q +++L E +R ++E DE N E +RL
Sbjct: 1676 KESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLE 1735
Query: 590 ESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEA 633
+ + E L +++ +++LN++ + ++ L+ +L A
Sbjct: 1736 ARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSA 1779
Score = 33.1 bits (72), Expect = 3.5
Identities = 64/334 (19%), Positives = 130/334 (38%), Gaps = 25/334 (7%)
Query: 172 LTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNAN-----ETMALQLRTK--E 224
L +K K+ E +L +++ + L+E N + + L+ E M +L K E
Sbjct: 862 LKVKEKQTKVEGEL--EEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQE 919
Query: 225 LSCALSDLNT--QNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRA 282
L L DL + + E R QI + + A+ + K A
Sbjct: 920 LEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEK---VTA 976
Query: 283 EHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDN 342
E ++K E ++ LE + E +E + E+ + L K+ +
Sbjct: 977 EAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEE-EEKAKNLAKIRNKQEVM 1035
Query: 343 TTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDS 402
+ LE+ EK + + I +++ +++ +L + E++ +
Sbjct: 1036 ISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGA 1095
Query: 403 IE--EKKTLQEN-----IDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTK 455
+ + +TL +N + +L+ + E + +D E + + K+ + +ELE+ K
Sbjct: 1096 LARGDDETLHKNNALKVVRELQAQIAELQ---EDFESEKASRNKAEKQKRDLSEELEALK 1152
Query: 456 TDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
T+LE + L ++ +E+ ELK L E
Sbjct: 1153 TELEDTLDTTAAQQELRTKREQEVAELKKALEEE 1186
>AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein
protein.
Length = 2018
Score = 62.1 bits (144), Expect = 7e-09
Identities = 120/607 (19%), Positives = 236/607 (38%), Gaps = 52/607 (8%)
Query: 17 LYEDLNEQESITSESHKITKLKTVWQEKMVT-FEKSKKELEDRQNQVMELYASLRNTHRK 75
L E L++ ES E + ++ ++KM + +++L++ + +L K
Sbjct: 962 LEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAK 1021
Query: 76 MKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNI 135
+K + +++ L + + KL +++ + C+ A E N + K+ N
Sbjct: 1022 IKKMEEEILLLEDQNSKFIKEKKLMEDRIAE-CSS--QLAEEEEKAKN-----LAKIRNK 1073
Query: 136 PNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRT 195
++ EE L K ++ E + G T L +I E A+ +D+L+
Sbjct: 1074 QEVMISDLEERLKKEEKTRQELEKAKRKLDG-ETTDLQDQIAELQAQ-------IDELKL 1125
Query: 196 EFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANR 255
+ K+ ++ L + +ET+ K + +L Q AE+++ S R A +
Sbjct: 1126 QLAKKEEELQGALARGDDETLHKNNALK----VVRELQAQIAELQEDFESEKASRNKAEK 1181
Query: 256 NXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVER-VVQLEAALEQARSESWSLERTV 314
+ + A+ +L+T E+ V +L+ ALE+ E+ + E +
Sbjct: 1182 QKRDLSEELEALKTELEDTLDT--TAAQQELRTKREQEVAELKKALEE---ETKNHEAQI 1236
Query: 315 XXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASY 374
E+ ++L + + K N + K + S
Sbjct: 1237 QDMRQRHATALEELSEQLEQ-AKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHK 1295
Query: 375 NKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVREL 434
K + E++ AK+ E ++ + E+ LQ +D++ T L E+E + ++
Sbjct: 1296 RKKLDAQVQELH---AKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDA 1352
Query: 435 DEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE-----------LK 483
ES L+ Q + +E K +L R ++EE K L E+ EE +E L+
Sbjct: 1353 ASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQ 1412
Query: 484 SKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLRE 543
S+L+ K D R + Y++L KN++ Q
Sbjct: 1413 SQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQ--- 1469
Query: 544 FGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKE 603
L+D+ ++ QR L K+Q+++D+ L +++ R E E +E
Sbjct: 1470 -----ELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAE--AEARE 1522
Query: 604 KEIKMLN 610
KE K L+
Sbjct: 1523 KETKALS 1529
Score = 46.0 bits (104), Expect = 5e-04
Identities = 59/300 (19%), Positives = 129/300 (43%), Gaps = 19/300 (6%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD 435
K++ ++++ + I+ L E KK + +E + + +D TDL + ++ +L ++D
Sbjct: 1065 KNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQD---QIAELQAQID 1121
Query: 436 E-KESILETKQCVQKELESTKTDLEHRKTEIEEYKRL---LFEKGEEIDELK-SKLSTEK 490
E K + + ++ +Q L + H+ ++ + L + E E+ + K S+ EK
Sbjct: 1122 ELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEK 1181
Query: 491 AIKDIXXXXXXXXXXXXXXXXXXXXXX---XXRESQM----KSYYEELMNLKNQITQLRE 543
+D+ RE ++ K+ EE N + QI +R+
Sbjct: 1182 QKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQ 1241
Query: 544 FGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKE 603
A L ++ + Q + L K ++ + + E+K L + E EH K +
Sbjct: 1242 RHA-TALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLD 1300
Query: 604 KEIKMLNEKEEEHMNI-INLLHNKLELRNEAD-IDVIITLAKYKKSLTLVLEKMSISNRV 661
+++ L+ K E + + L +L+NE D + ++ A+ KK + + S+ +++
Sbjct: 1301 AQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAE-KKGIKFAKDAASLESQL 1359
Score = 41.5 bits (93), Expect = 0.010
Identities = 47/226 (20%), Positives = 93/226 (41%), Gaps = 9/226 (3%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKE 450
+L E+E+K+ +EEK L E + E+E L + E E IL + +E
Sbjct: 916 ELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEE 975
Query: 451 LESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXX 510
E L++ K +++ + + L E+ +E + + KL EK +
Sbjct: 976 EEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEK----VTAEAKIKKMEEEILL 1031
Query: 511 XXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKR 570
+E ++ + + +Q+ + E NL + N L E K+
Sbjct: 1032 LEDQNSKFIKEKKLME--DRIAECSSQLAEEEE--KAKNLAKIRNKQEVMISDLEERLKK 1087
Query: 571 QEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM-LNEKEEE 615
+E+ ++L+ + ++ + +Q L + E+K+ L +KEEE
Sbjct: 1088 EEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEE 1133
Score = 38.7 bits (86), Expect = 0.070
Identities = 101/527 (19%), Positives = 215/527 (40%), Gaps = 49/527 (9%)
Query: 6 LEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMEL 65
LE Q T L E+ ++ +++S ++ + K QE+ E+++K LE QV+ L
Sbjct: 1355 LESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLE---KQVLAL 1411
Query: 66 YASLRNTHRKMKL-LGQKVNLPSAEELHIMNVAKLSP---EQLLQLCAGGEPKALEHSTL 121
+ L +T +K+ LG +L A++ + + LS E+ L + K L
Sbjct: 1412 QSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQEL 1471
Query: 122 DNKVTFDVNKLLNIPNSLVDK---CEETLFKRKEIINWFES------LMSQEKGISTKTL 172
D+ +T D++ + ++L K ++ L + K I + ++EK +L
Sbjct: 1472 DD-LTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSL 1530
Query: 173 TMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANET----MALQLRTKELSCA 228
++E + + QLR + ++++ D + KN +E AL+ + +E+
Sbjct: 1531 ARALEEALEAKEEFERQNKQLRAD-MEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQ 1589
Query: 229 LSDLN-----TQNAEMRKQIH----SGDHHRPYANR---NXXXXXXXXXXXXXXXXSIMK 276
L +L T++A++R +++ R R N +
Sbjct: 1590 LEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELED 1649
Query: 277 DRLSRA-----EHQLKTNVERV-VQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQ 330
+R RA + +++ +++ + Q+EAA +AR E R + E+
Sbjct: 1650 ERKQRALAVASKKKMEIDLKDLEAQIEAA-NKARDEVIKQLRKLQAQMKDYQRELEEARA 1708
Query: 331 ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIA 390
+++ K++ L+ + +LQ ++ ++ + + A
Sbjct: 1709 SRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSA 1768
Query: 391 KLIE---IEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCV 447
L E +E + EE + Q N++ L ++ L+V L EL + S +
Sbjct: 1769 LLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNA 1828
Query: 448 QKELESTKTDLEHRKTEIE-----EYKRLLFEKGEEIDELKSKLSTE 489
+++LE +L+ + E+E ++K + +I +L+ +L E
Sbjct: 1829 RQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQE 1875
Score = 37.9 bits (84), Expect = 0.12
Identities = 44/182 (24%), Positives = 84/182 (46%), Gaps = 24/182 (13%)
Query: 326 EDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEM 385
E ++ KL + + + LE+ ALA +KL+ + D+ H+
Sbjct: 1430 ESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTV-------DLDHQR 1482
Query: 386 NLNIAKLIEIEKKYNDSIEEKKTLQ----ENIDDLRTDLLESELRVKDLVRELDE----K 437
+ + L + +KK++ + E+K++ E D + E E + L R L+E K
Sbjct: 1483 QV-ASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAK 1541
Query: 438 ESILETKQCVQKELE---STKTDLEHRKTEIEEYKRLLFEKGEE----IDELKSKL-STE 489
E + ++ ++E S+K D+ E+E+ KR L ++ EE ++EL+ +L +TE
Sbjct: 1542 EEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATE 1601
Query: 490 KA 491
A
Sbjct: 1602 DA 1603
Score = 35.9 bits (79), Expect = 0.49
Identities = 55/318 (17%), Positives = 123/318 (38%), Gaps = 17/318 (5%)
Query: 167 ISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELS 226
I K L +I+ N D + L +L+ + +K+ ++ R + +E A ++KE
Sbjct: 1666 IDLKDLEAQIEAANKARDEVIKQLRKLQAQ-MKDYQRELEEARASRDEIFA---QSKESE 1721
Query: 227 CALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIM--KDRLSRAEH 284
L L + ++++++ S + R +A + +++ K RL
Sbjct: 1722 KKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIA 1781
Query: 285 QLKTNVERVVQ-LEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNT 343
QL+ +E +E ++ R + ++ T+ + D +L + K+
Sbjct: 1782 QLEEELEEEQSNMELLNDRFRKTTLQVD-TLNAELAAERSAAQKSDNARQQLERQNKELK 1840
Query: 344 THLEDIALA-REKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDS 402
L+++ A + K ++ + K+ L + EKK +
Sbjct: 1841 AKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKL----VRRTEKKLKEI 1896
Query: 403 IEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKES----ILETKQCVQKELESTKTDL 458
+ + + + D + + ++ R+K L R+L+E E +++ +Q+EL+
Sbjct: 1897 FMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEAN 1956
Query: 459 EHRKTEIEEYKRLLFEKG 476
E E+ K L G
Sbjct: 1957 EGLSREVSTLKNRLRRGG 1974
Score = 34.7 bits (76), Expect = 1.1
Identities = 55/284 (19%), Positives = 121/284 (42%), Gaps = 30/284 (10%)
Query: 374 YNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRE 433
+ + K ++ +M ++ ++ K ++ + K+ L++ ++++RT L E E +L
Sbjct: 1544 FERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELE---DELQAT 1600
Query: 434 LDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI-----DELKSK--- 485
D K + Q ++ + E DL+ R + EE KRLL ++ E+ DE K +
Sbjct: 1601 EDAKLRLEVNMQAMKAQFER---DLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALA 1657
Query: 486 LSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQL--RE 543
++++K ++ ++QMK Y EL + ++ +
Sbjct: 1658 VASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQS 1717
Query: 544 FGAFDNLNDVGNMINQQRDKLF--ELTKR--QEEYDEKLQTKEN----------EIKRLV 589
+ L + I Q +++L E +R ++E DE N E +RL
Sbjct: 1718 KESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLE 1777
Query: 590 ESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEA 633
+ + E L +++ +++LN++ + ++ L+ +L A
Sbjct: 1778 ARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSA 1821
Score = 33.1 bits (72), Expect = 3.5
Identities = 64/334 (19%), Positives = 130/334 (38%), Gaps = 25/334 (7%)
Query: 172 LTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNAN-----ETMALQLRTK--E 224
L +K K+ E +L +++ + L+E N + + L+ E M +L K E
Sbjct: 904 LKVKEKQTKVEGEL--EEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQE 961
Query: 225 LSCALSDLNT--QNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRA 282
L L DL + + E R QI + + A+ + K A
Sbjct: 962 LEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEK---VTA 1018
Query: 283 EHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDN 342
E ++K E ++ LE + E +E + E+ + L K+ +
Sbjct: 1019 EAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEE-EEKAKNLAKIRNKQEVM 1077
Query: 343 TTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDS 402
+ LE+ EK + + I +++ +++ +L + E++ +
Sbjct: 1078 ISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGA 1137
Query: 403 IE--EKKTLQEN-----IDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTK 455
+ + +TL +N + +L+ + E + +D E + + K+ + +ELE+ K
Sbjct: 1138 LARGDDETLHKNNALKVVRELQAQIAELQ---EDFESEKASRNKAEKQKRDLSEELEALK 1194
Query: 456 TDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
T+LE + L ++ +E+ ELK L E
Sbjct: 1195 TELEDTLDTTAAQQELRTKREQEVAELKKALEEE 1228
>AB209693-1|BAD92930.1| 1310|Homo sapiens golgi autoantigen, golgin
subfamily a, 4 variant protein.
Length = 1310
Score = 61.7 bits (143), Expect = 9e-09
Identities = 118/633 (18%), Positives = 268/633 (42%), Gaps = 51/633 (8%)
Query: 28 TSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPS 87
TSE +I+ + + + K + KK E++ ++ +L+ + RK + L +K+
Sbjct: 478 TSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHE--KELARKEQELTKKLQTRE 535
Query: 88 AEELHIMNVA-KLSPEQLLQLCAGGEPK---ALEHSTLDNK--VTFDVNKLLNIPNS--- 138
E M VA + S + L++ E + ALE L K +T NKL ++
Sbjct: 536 REFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAET 595
Query: 139 -------LVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLD 191
L E++L + K + EK K +T+ +++ E + LK D
Sbjct: 596 YRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQD 655
Query: 192 QLRTEFLKEINDI----IDCLRKNANETMALQLRTKEL--SCALSDLNTQNAEMRKQIHS 245
L TE L+ + ++ LR+ + L+ KE+ + ++N + E + +
Sbjct: 656 ALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLE-KLDVKQ 714
Query: 246 GDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARS 305
+ + + S++KD+ + + +L+ ++ Q +Q S
Sbjct: 715 TELE---SLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDE--QKNHHQQQVDS 769
Query: 306 ESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLE----DIALAREKLQSXXX 361
E ++ + L + + +K++ H+E DI + +LQ
Sbjct: 770 IIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASA 829
Query: 362 XXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLL 421
SA++ ++ K + ++ KL+++E + ++ ++ D+ T+L
Sbjct: 830 KLDVFQSYQSATHEQT-KAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELD 888
Query: 422 ESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE 481
+++V+DL+++L+++ S +E K V+ + ++ LE E E+ K++L EK I
Sbjct: 889 AHKIQVQDLMQQLEKQNSEMEQK--VKSLTQVYESKLEDGNKEQEQTKQILVEKENMI-- 944
Query: 482 LKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQL 541
L+ + +K I+ + E++ K+ +++ +K + ++
Sbjct: 945 LQMREGQKKEIEILTQKLSAKEDSIHILNEEY-------ETKFKNQEKKMEKVKQKAKEM 997
Query: 542 REFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEK-LQTKENEIKRLVESMTEQEHVLN 600
+E L+ + + + EL++++++++ K L+ + + ++++ E N
Sbjct: 998 QETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLE--TN 1055
Query: 601 KKEKEIKMLNEKEEEHMN-IINLLHNKLELRNE 632
+KE +I+ L E +N +I++ KL + E
Sbjct: 1056 QKE-QIESLTEVHRRELNDVISIWEKKLNQQAE 1087
Score = 48.4 bits (110), Expect = 9e-05
Identities = 92/495 (18%), Positives = 198/495 (40%), Gaps = 27/495 (5%)
Query: 3 QEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQV 62
+EEL + ++QTD + ++L E + ++H ++ ++ +E V+ ++++K L+D+ NQ
Sbjct: 735 EEELSVLKDQTDK-MKQEL-EAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQ- 791
Query: 63 MELYASLRNTHRK---MKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHS 119
+EL R+ H K + + ++ +E AKL Q Q + KA E
Sbjct: 792 LELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQ 851
Query: 120 TLDNKVTFDVNKLLNIPNS---LVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKI 176
+ KLL++ L + E ++K++ ++ I + L ++
Sbjct: 852 LAQLQ-----QKLLDLETERILLTKQVAEVEAQKKDVCTELDA-----HKIQVQDLMQQL 901
Query: 177 KEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRK--NANETMALQLRTKELSCALSDLNT 234
++ N+E + SL Q+ L++ N + ++ E M LQ+R + + L
Sbjct: 902 EKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKK-EIEILTQ 960
Query: 235 QNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVV 294
+ + IH + +N +K +L E +LK +E
Sbjct: 961 KLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTA 1020
Query: 295 QLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLED-IALAR 353
LE + ++ + + LE + ++ + + L D I++
Sbjct: 1021 -LELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWE 1079
Query: 354 EKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENI 413
+KL + + ++K ++ L + E+ K+ EE +
Sbjct: 1080 KKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTL 1139
Query: 414 DDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLF 473
++L+ L + V L ++ + ++ LE ++ +L + + + ++ E K L
Sbjct: 1140 NELQEQLKQKSAHVNSLAQDETKLKAHLEK---LEVDLNKSLKENTFLQEQLVELKMLAE 1196
Query: 474 EKGEEIDELKSKLST 488
E ++ EL SKL T
Sbjct: 1197 EDKRKVSELTSKLKT 1211
Score = 41.5 bits (93), Expect = 0.010
Identities = 113/639 (17%), Positives = 243/639 (38%), Gaps = 41/639 (6%)
Query: 22 NEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMK-LLG 80
+E E + S + K + + +++ E+S + ++++ Y L+ +K++ +L
Sbjct: 153 SEAEDLVGNSDSLNKEQLI--QRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILS 210
Query: 81 QKVN------LPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLN 134
Q + EEL + AK ++ + A E K S L +V+ +L N
Sbjct: 211 QSQDKSLRRIAELREELQMDQQAKKHLQE--EFDASLEEKDQYISVLQTQVSLLKQRLRN 268
Query: 135 IPNSL-VDKCEETLFKRKEIINWFESLMSQ-----EKGISTKTLTMKIKEFNAENDLLKS 188
P ++ V K L + E+ E+ S E G S KTL + + +LLK
Sbjct: 269 GPMNVDVLKPLPQLEPQAEVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKR 328
Query: 189 SLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDH 248
+ +++ KE ++ ++ E L R +EL + DL+ AE K I
Sbjct: 329 CKETIQSH--KEQCTLLTSEKEALQEQ--LDERLQELE-KIKDLHM--AEKTKLI---TQ 378
Query: 249 HRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESW 308
R N M + L E ++ R+ Q+ E+ R +
Sbjct: 379 LRDAKNLIEQLEQDKGMVIAETKRQ-MHETLEMKEEEIAQLRSRIKQMTTQGEELREQKE 437
Query: 309 SLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXX 368
ER + ++ KL + + +E + E++
Sbjct: 438 KSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTS-EEERISLQQELSRVKQE 496
Query: 369 XXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVK 428
S + + L+ +L E++ ++ ++ +E + ++ L +S+
Sbjct: 497 VVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTRE--REFQEQMKVALEKSQSEYL 554
Query: 429 DLVRELDEKESILETKQCVQKE--LESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKL 486
+ +E +++ES+ + +QK+ L ++ L + E E Y+ + E ++ KS
Sbjct: 555 KISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLE--KSLQ 612
Query: 487 STEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGA 546
+ KD+ +K + L K Q+ + +
Sbjct: 613 ENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTE 672
Query: 547 FDNLNDVGNMINQQ--RDK--LFE--LTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLN 600
+ L + + +DK +F+ + + E+ EKL K+ E++ L ++E +
Sbjct: 673 MEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARH 732
Query: 601 KKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVII 639
K E+E+ +L ++ ++ + ++ + ++ +D II
Sbjct: 733 KLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSII 771
Score = 41.5 bits (93), Expect = 0.010
Identities = 63/349 (18%), Positives = 144/349 (41%), Gaps = 18/349 (5%)
Query: 275 MKDRLSRAEHQLKTNVERVVQL-EAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELN 333
+ +L + +++ V+ + Q+ E+ LE E ++ + E +E+
Sbjct: 897 LMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIE 956
Query: 334 KLTQ--SIKDNTTHL--EDIALAREKLQSXXXXXXXXXXXXSASYNKSIKD----MKHEM 385
LTQ S K+++ H+ E+ + + + K + D +K E+
Sbjct: 957 ILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKEL 1016
Query: 386 NLNIAKLIEIEKKYNDSIEEKKT-----LQENIDDLRTDLLESELRVKDLVR-ELDEKES 439
+L + EK++N + E + + + L T+ E + ++ R EL++ S
Sbjct: 1017 ENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVIS 1076
Query: 440 ILETKQCVQKE--LESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXX 497
I E K Q E E + L+ ++ E+ E K+ + G E +E+ +++ K
Sbjct: 1077 IWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQD 1136
Query: 498 XXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMI 557
E+++K++ E+L N+ + F + L ++ +
Sbjct: 1137 TTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTF-LQEQLVELKMLA 1195
Query: 558 NQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEI 606
+ + K+ ELT + + DE+ Q+ ++ ++ +S+ ++ K +E+
Sbjct: 1196 EEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEEL 1244
>AB053470-1|BAC54109.1| 1088|Homo sapiens ELKS delta protein.
Length = 1088
Score = 61.7 bits (143), Expect = 9e-09
Identities = 116/644 (18%), Positives = 256/644 (39%), Gaps = 60/644 (9%)
Query: 3 QEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQV 62
++++E+++++ L +N ++ S K + + +T K + + +NQ
Sbjct: 169 RKDVEVKESK----LSSSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQH 224
Query: 63 MEL-YASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTL 121
M++ +L++ R + L Q S+ VA+L+ E +L A E +A E
Sbjct: 225 MQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKE---- 280
Query: 122 DNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTL------TMK 175
F + K L ++ ++TL R E I ++ Q KG+S K T +
Sbjct: 281 ----LFLLRKTLEEMELRIETQKQTLNARDESIKKLLEML-QSKGLSAKATEEDHERTRR 335
Query: 176 IKEFNAENDLLKSSLDQ-------LRTEFLKEINDIIDCLRKNANETMALQLRTKELSCA 228
+ E L+S L+Q LR E + + D + A +T+ ++++ ++S
Sbjct: 336 LAEAEMHVHHLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTV-IEMKDSKISSM 394
Query: 229 LSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKT 288
L E++ +G + MK+++ + + +L
Sbjct: 395 ERGLRDLEEEIQMLKSNGA-----LSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSR 449
Query: 289 NVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXED---FDQELNKLTQSIKDNTTH 345
++ L+ LE ++ ++ + + E++ L +++ T
Sbjct: 450 KDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETM 509
Query: 346 LEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH-EMNLNIAKLIEIEKKYNDSIE 404
L ++ Q K + D+K ++N+ K+ ++++ D +
Sbjct: 510 LN-----KKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEK 564
Query: 405 EKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTE 464
+ +L+E + L+ D ++ + L L EKE +E + E D ++ E
Sbjct: 565 QMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLK------EQRDRDEREKQEE 618
Query: 465 IEEYKRLLFEKGEEIDELKSKLSTEKA-IKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQ 523
I+ YK+ L + E++ L+ LS ++A + D+ E
Sbjct: 619 IDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTL----EIA 674
Query: 524 MKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKEN 583
++ EE + +++Q+ + E A + + D++ L + Y ++ +
Sbjct: 675 LEQKKEECLKMESQLKKAHE-AALE-----ARASPEMSDRIQHLEREITRYKDESSKAQA 728
Query: 584 EIKRLVESMTEQEHVLNKKEKEIKMLNEK-EEEHMNIINLLHNK 626
E+ RL+E + E E+ N K+K+I L + ++++ + NL H +
Sbjct: 729 EVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKE 772
Score = 46.0 bits (104), Expect = 5e-04
Identities = 51/219 (23%), Positives = 96/219 (43%), Gaps = 15/219 (6%)
Query: 280 SRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXX-----EDFDQELNK 334
S A LK + R+ LE ALEQ + E +E + D Q L +
Sbjct: 656 SLASSGLKKD-SRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLER 714
Query: 335 LTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEM-NLNIAKLI 393
KD ++ + ++ A + +KD ++ NL + +
Sbjct: 715 EITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQV 774
Query: 394 EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDE--KESILET--KQCVQK 449
E +KK +EE + ++N++D L +S + D + EL+E +ES+ T ++ V
Sbjct: 775 E-KKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLA 833
Query: 450 ELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLST 488
+ ES +T+ E ++EE + + +E++ +K+KLS+
Sbjct: 834 QEESARTNAE---KQVEELLMAMEKVKQELESMKAKLSS 869
Score = 36.3 bits (80), Expect = 0.37
Identities = 48/248 (19%), Positives = 104/248 (41%), Gaps = 11/248 (4%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENID--DLRTDLLESELRVKDLVRELDEKESILETKQCVQ 448
KL + +++DS + + L+E++ + R +L++E V L L+EKE++L K
Sbjct: 460 KLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTE--VDALRLRLEEKETMLNKK---T 514
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXX 508
K+++ + + EI + K +L K +++ L+ K+ +++
Sbjct: 515 KQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIEN---LQEQLRDKEKQMSSLKE 571
Query: 509 XXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELT 568
++ + + E L + I +L+E D + N ++D L +L
Sbjct: 572 RVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKD-LKDLK 630
Query: 569 KRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
++ L KE + L E + KK+ +K L E+ + ++L+
Sbjct: 631 EKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLK 690
Query: 629 LRNEADID 636
+EA ++
Sbjct: 691 KAHEAALE 698
Score = 35.1 bits (77), Expect = 0.86
Identities = 84/502 (16%), Positives = 198/502 (39%), Gaps = 31/502 (6%)
Query: 1 MKQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQN 60
+ EE E + Q + + I ++++ T E + D +
Sbjct: 414 LSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQ 473
Query: 61 QVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHST 120
+ L SL ++ +L +V+ A L + + ++ Q+ E K +
Sbjct: 474 HIEVLKESLTAKEQRAAILQTEVD---ALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGE 530
Query: 121 L-DNKVTFDVN-KLLNIPNSLVDKCEETLF-KRKEIINWFESLMS-QEKGISTKTLTMKI 176
+ D K DV + +N+ ++ +E L K K++ + E + S Q +T T +
Sbjct: 531 IHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTL 590
Query: 177 KEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQN 236
+E AE + L + R +E + ID +K+ + L+ + L LS+
Sbjct: 591 EEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKD---LKEKVSLLQGDLSEKEASL 647
Query: 237 AEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSI-MKDRLSRA-EHQLKTNV---- 290
++++ H+ ++ + M+ +L +A E L+
Sbjct: 648 LDLKE--HASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEM 705
Query: 291 -ERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXE---DFDQELNKLTQSIKDNTTHL 346
+R+ LE + + + ES + V D D+++ +L + +KD +
Sbjct: 706 SDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKV 765
Query: 347 EDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIE-- 404
++ + + + N S + ++ + ++ E+E+ +S++
Sbjct: 766 ANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQIT 825
Query: 405 -EKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKT 463
E++ + + RT+ +E +V++L+ +++ + LE+ ++ +L ST+ L ++T
Sbjct: 826 AEREMVLAQEESARTN---AEKQVEELLMAMEKVKQELES---MKAKLSSTQQSLAEKET 879
Query: 464 EIEEYKRLLFEKGEEIDELKSK 485
+ + + EE+ E+K +
Sbjct: 880 HLTNLRAERRKHLEEVLEMKQE 901
>BC118918-1|AAI18919.1| 1302|Homo sapiens cingulin-like 1 protein.
Length = 1302
Score = 61.3 bits (142), Expect = 1e-08
Identities = 72/364 (19%), Positives = 152/364 (41%), Gaps = 25/364 (6%)
Query: 273 SIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQEL 332
S ++ RL +E +L+ N+E + Q++ EQ ++E L+ + D+E
Sbjct: 666 STLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREK 725
Query: 333 NKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMN----LN 388
L + + L+D+ +A+E+ + + + + EM+
Sbjct: 726 GALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQY 785
Query: 389 IAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEK-----ESILET 443
A+L + + ++ + + L + D +E+RVK L++E +EK E +
Sbjct: 786 DAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVK-LLQEENEKLQGRSEELERR 844
Query: 444 KQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI----DELKSKLSTEKAIKDIXXXX 499
+Q+++E K D K +++Y+ + + E + E K +S +A+++
Sbjct: 845 VAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALEN-ELEA 903
Query: 500 XXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLR-EFG-AFDNL-NDVGNM 556
ES+ K E+L LKN++ R G + L ++ ++
Sbjct: 904 AQGNLSQTTQEQKQLSEKLKEESEQK---EQLRRLKNEMENERWHLGKTIEKLQKEMADI 960
Query: 557 INQQRDKLFELTKRQEEYDEKLQTKENEIKR-LVESMTEQEH---VLNKKEKEIKMLNEK 612
+ R EL + +EY EK + + E++R L E E E K + E++++ E+
Sbjct: 961 VEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEE 1020
Query: 613 EEEH 616
++
Sbjct: 1021 LRDY 1024
Score = 50.8 bits (116), Expect = 2e-05
Identities = 98/540 (18%), Positives = 213/540 (39%), Gaps = 43/540 (7%)
Query: 144 EETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEIND 203
E+ L KR+ + + + +E + + ++++AE L+ S++ E K +
Sbjct: 750 EDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVE----EATKNVEV 805
Query: 204 IIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXX 263
+ + + ++R K L L ++ E+ +++ +
Sbjct: 806 LASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKET 865
Query: 264 XXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXX 323
+ ++ L A + K V LE LE A+ +L +T
Sbjct: 866 LKKYEGEIRQL-EEALVHARKEEKEAVSARRALENELEAAQG---NLSQTTQEQKQLSEK 921
Query: 324 XXEDFDQ--ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDM 381
E+ +Q +L +L +++ HL EKLQ + + +
Sbjct: 922 LKEESEQKEQLRRLKNEMENERWHLGKTI---EKLQKEMADIVEASRTSTLELQNQLDEY 978
Query: 382 KHEMNLNIAKLI-EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESI 440
K + +A++ ++++K ++ + + T + D++R L+E ELR D R DE
Sbjct: 979 KEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMR--LMEEELR--DYQRAQDEA--- 1031
Query: 441 LETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXX 500
L +Q +++ L+ + +LE + ++ RL+ + +++ +L+ +L E+ D+
Sbjct: 1032 LTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERI 1091
Query: 501 XXXXXXXXXXXXXXXXXXXRESQMK----SYYEELMNLKNQITQLREFGAFDNLNDVGNM 556
++ S + +LK++I L G++ + + +
Sbjct: 1092 SRSREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLE--GSYRSSKE--GL 1147
Query: 557 INQQRDKLFELTKR--QEEYDE-KLQTKENEIKRLVE-----------SMTEQEHVLNKK 602
+ Q ++ EL R EE D LQ ++R V+ S+T+Q+ L+ +
Sbjct: 1148 VVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLR 1207
Query: 603 EKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVL 662
K +K E+ EE ++ + KL+ E +D+ L S+ L + ++VL
Sbjct: 1208 LKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPSKVL 1267
Score = 50.4 bits (115), Expect = 2e-05
Identities = 63/265 (23%), Positives = 115/265 (43%), Gaps = 25/265 (9%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD 435
K+ +++K E A L E+ ++N+ +EE TLQ+ +++ E ELR + L+
Sbjct: 635 KNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEE-----SEGELR-----KNLE 684
Query: 436 EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLL-FEKGEEIDELKSKLSTEKAIKD 494
E + ++ Q E+ + L E++ KR EKG I+EL L ++ ++D
Sbjct: 685 ELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEEL---LQAKQDLQD 741
Query: 495 IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQ----ITQLREF--GAFD 548
+ + ++ S+ +E+ LK Q + LRE A
Sbjct: 742 LLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATK 801
Query: 549 NLNDVGNMIN--QQRDKLFEL-TKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKE 605
N+ + + N +Q E+ K +E +EKLQ + E++R V + Q L E +
Sbjct: 802 NVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAK 861
Query: 606 IKMLNEKEEEHMNIIN--LLHNKLE 628
K +K E + + L+H + E
Sbjct: 862 AKETLKKYEGEIRQLEEALVHARKE 886
Score = 36.7 bits (81), Expect = 0.28
Identities = 27/123 (21%), Positives = 65/123 (52%), Gaps = 11/123 (8%)
Query: 521 ESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYD----- 575
E +++ EEL +K + Q + + D+ + +++ D+L + KR E+ +
Sbjct: 676 EGELRKNLEELFQVKMEREQHQT-----EIRDLQDQLSEMHDEL-DSAKRSEDREKGALI 729
Query: 576 EKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADI 635
E+L + +++ L+ + EQE +L K+E+E+ L +E ++ + +KL+ + +A++
Sbjct: 730 EELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAEL 789
Query: 636 DVI 638
+
Sbjct: 790 QAL 792
>BC112049-1|AAI12050.1| 1302|Homo sapiens cingulin-like 1 protein.
Length = 1302
Score = 61.3 bits (142), Expect = 1e-08
Identities = 72/364 (19%), Positives = 152/364 (41%), Gaps = 25/364 (6%)
Query: 273 SIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQEL 332
S ++ RL +E +L+ N+E + Q++ EQ ++E L+ + D+E
Sbjct: 666 STLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREK 725
Query: 333 NKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMN----LN 388
L + + L+D+ +A+E+ + + + + EM+
Sbjct: 726 GALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQY 785
Query: 389 IAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEK-----ESILET 443
A+L + + ++ + + L + D +E+RVK L++E +EK E +
Sbjct: 786 DAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVK-LLQEENEKLQGRSEELERR 844
Query: 444 KQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI----DELKSKLSTEKAIKDIXXXX 499
+Q+++E K D K +++Y+ + + E + E K +S +A+++
Sbjct: 845 VAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALEN-ELEA 903
Query: 500 XXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLR-EFG-AFDNL-NDVGNM 556
ES+ K E+L LKN++ R G + L ++ ++
Sbjct: 904 AQGNLSQTTQEQKQLSEKLKEESEQK---EQLRRLKNEMENERWHLGKTIEKLQKEMADI 960
Query: 557 INQQRDKLFELTKRQEEYDEKLQTKENEIKR-LVESMTEQEH---VLNKKEKEIKMLNEK 612
+ R EL + +EY EK + + E++R L E E E K + E++++ E+
Sbjct: 961 VEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEE 1020
Query: 613 EEEH 616
++
Sbjct: 1021 LRDY 1024
Score = 50.8 bits (116), Expect = 2e-05
Identities = 98/540 (18%), Positives = 213/540 (39%), Gaps = 43/540 (7%)
Query: 144 EETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEIND 203
E+ L KR+ + + + +E + + ++++AE L+ S++ E K +
Sbjct: 750 EDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVE----EATKNVEV 805
Query: 204 IIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXX 263
+ + + ++R K L L ++ E+ +++ +
Sbjct: 806 LASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKET 865
Query: 264 XXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXX 323
+ ++ L A + K V LE LE A+ +L +T
Sbjct: 866 LKKYEGEIRQL-EEALVHARKEEKEAVSARRALENELEAAQG---NLSQTTQEQKQLSEK 921
Query: 324 XXEDFDQ--ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDM 381
E+ +Q +L +L +++ HL EKLQ + + +
Sbjct: 922 LKEESEQKEQLRRLKNEMENERWHLGKTI---EKLQKEMADIVEASRTSTLELQNQLDEY 978
Query: 382 KHEMNLNIAKLI-EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESI 440
K + +A++ ++++K ++ + + T + D++R L+E ELR D R DE
Sbjct: 979 KEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMR--LMEEELR--DYQRAQDEA--- 1031
Query: 441 LETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXX 500
L +Q +++ L+ + +LE + ++ RL+ + +++ +L+ +L E+ D+
Sbjct: 1032 LTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERI 1091
Query: 501 XXXXXXXXXXXXXXXXXXXRESQMK----SYYEELMNLKNQITQLREFGAFDNLNDVGNM 556
++ S + +LK++I L G++ + + +
Sbjct: 1092 SRSREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLE--GSYRSSKE--GL 1147
Query: 557 INQQRDKLFELTKR--QEEYDE-KLQTKENEIKRLVE-----------SMTEQEHVLNKK 602
+ Q ++ EL R EE D LQ ++R V+ S+T+Q+ L+ +
Sbjct: 1148 VVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLR 1207
Query: 603 EKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVL 662
K +K E+ EE ++ + KL+ E +D+ L S+ L + ++VL
Sbjct: 1208 LKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPSKVL 1267
Score = 50.4 bits (115), Expect = 2e-05
Identities = 63/265 (23%), Positives = 115/265 (43%), Gaps = 25/265 (9%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD 435
K+ +++K E A L E+ ++N+ +EE TLQ+ +++ E ELR + L+
Sbjct: 635 KNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEE-----SEGELR-----KNLE 684
Query: 436 EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLL-FEKGEEIDELKSKLSTEKAIKD 494
E + ++ Q E+ + L E++ KR EKG I+EL L ++ ++D
Sbjct: 685 ELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEEL---LQAKQDLQD 741
Query: 495 IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQ----ITQLREF--GAFD 548
+ + ++ S+ +E+ LK Q + LRE A
Sbjct: 742 LLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATK 801
Query: 549 NLNDVGNMIN--QQRDKLFEL-TKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKE 605
N+ + + N +Q E+ K +E +EKLQ + E++R V + Q L E +
Sbjct: 802 NVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAK 861
Query: 606 IKMLNEKEEEHMNIIN--LLHNKLE 628
K +K E + + L+H + E
Sbjct: 862 AKETLKKYEGEIRQLEEALVHARKE 886
Score = 36.7 bits (81), Expect = 0.28
Identities = 27/123 (21%), Positives = 65/123 (52%), Gaps = 11/123 (8%)
Query: 521 ESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYD----- 575
E +++ EEL +K + Q + + D+ + +++ D+L + KR E+ +
Sbjct: 676 EGELRKNLEELFQVKMEREQHQT-----EIRDLQDQLSEMHDEL-DSAKRSEDREKGALI 729
Query: 576 EKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADI 635
E+L + +++ L+ + EQE +L K+E+E+ L +E ++ + +KL+ + +A++
Sbjct: 730 EELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAEL 789
Query: 636 DVI 638
+
Sbjct: 790 QAL 792
>BC093827-1|AAH93827.1| 1302|Homo sapiens cingulin-like 1 protein.
Length = 1302
Score = 61.3 bits (142), Expect = 1e-08
Identities = 72/364 (19%), Positives = 152/364 (41%), Gaps = 25/364 (6%)
Query: 273 SIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQEL 332
S ++ RL +E +L+ N+E + Q++ EQ ++E L+ + D+E
Sbjct: 666 STLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREK 725
Query: 333 NKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMN----LN 388
L + + L+D+ +A+E+ + + + + EM+
Sbjct: 726 GALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQY 785
Query: 389 IAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEK-----ESILET 443
A+L + + ++ + + L + D +E+RVK L++E +EK E +
Sbjct: 786 DAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVK-LLQEENEKLQGRSEELERR 844
Query: 444 KQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI----DELKSKLSTEKAIKDIXXXX 499
+Q+++E K D K +++Y+ + + E + E K +S +A+++
Sbjct: 845 VAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALEN-ELEA 903
Query: 500 XXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLR-EFG-AFDNL-NDVGNM 556
ES+ K E+L LKN++ R G + L ++ ++
Sbjct: 904 AQGNLSQTTQEQKQLSEKLKEESEQK---EQLRRLKNEMENERWHLGKTIEKLQKEMADI 960
Query: 557 INQQRDKLFELTKRQEEYDEKLQTKENEIKR-LVESMTEQEH---VLNKKEKEIKMLNEK 612
+ R EL + +EY EK + + E++R L E E E K + E++++ E+
Sbjct: 961 VEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEE 1020
Query: 613 EEEH 616
++
Sbjct: 1021 LRDY 1024
Score = 50.8 bits (116), Expect = 2e-05
Identities = 98/540 (18%), Positives = 213/540 (39%), Gaps = 43/540 (7%)
Query: 144 EETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEIND 203
E+ L KR+ + + + +E + + ++++AE L+ S++ E K +
Sbjct: 750 EDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVE----EATKNVEV 805
Query: 204 IIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXX 263
+ + + ++R K L L ++ E+ +++ +
Sbjct: 806 LASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKET 865
Query: 264 XXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXX 323
+ ++ L A + K V LE LE A+ +L +T
Sbjct: 866 LKKYEGEIRQL-EEALVHARKEEKEAVSARRALENELEAAQG---NLSQTTQEQKQLSEK 921
Query: 324 XXEDFDQ--ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDM 381
E+ +Q +L +L +++ HL EKLQ + + +
Sbjct: 922 LKEESEQKEQLRRLKNEMENERWHLGKTI---EKLQKEMADIVEASRTSTLELQNQLDEY 978
Query: 382 KHEMNLNIAKLI-EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESI 440
K + +A++ ++++K ++ + + T + D++R L+E ELR D R DE
Sbjct: 979 KEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMR--LMEEELR--DYQRAQDEA--- 1031
Query: 441 LETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXX 500
L +Q +++ L+ + +LE + ++ RL+ + +++ +L+ +L E+ D+
Sbjct: 1032 LTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERI 1091
Query: 501 XXXXXXXXXXXXXXXXXXXRESQMK----SYYEELMNLKNQITQLREFGAFDNLNDVGNM 556
++ S + +LK++I L G++ + + +
Sbjct: 1092 SRSREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLE--GSYRSSKE--GL 1147
Query: 557 INQQRDKLFELTKR--QEEYDE-KLQTKENEIKRLVE-----------SMTEQEHVLNKK 602
+ Q ++ EL R EE D LQ ++R V+ S+T+Q+ L+ +
Sbjct: 1148 VVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLR 1207
Query: 603 EKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVL 662
K +K E+ EE ++ + KL+ E +D+ L S+ L + ++VL
Sbjct: 1208 LKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPSKVL 1267
Score = 50.4 bits (115), Expect = 2e-05
Identities = 63/265 (23%), Positives = 115/265 (43%), Gaps = 25/265 (9%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD 435
K+ +++K E A L E+ ++N+ +EE TLQ+ +++ E ELR + L+
Sbjct: 635 KNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEE-----SEGELR-----KNLE 684
Query: 436 EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLL-FEKGEEIDELKSKLSTEKAIKD 494
E + ++ Q E+ + L E++ KR EKG I+EL L ++ ++D
Sbjct: 685 ELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEEL---LQAKQDLQD 741
Query: 495 IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQ----ITQLREF--GAFD 548
+ + ++ S+ +E+ LK Q + LRE A
Sbjct: 742 LLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATK 801
Query: 549 NLNDVGNMIN--QQRDKLFEL-TKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKE 605
N+ + + N +Q E+ K +E +EKLQ + E++R V + Q L E +
Sbjct: 802 NVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAK 861
Query: 606 IKMLNEKEEEHMNIIN--LLHNKLE 628
K +K E + + L+H + E
Sbjct: 862 AKETLKKYEGEIRQLEEALVHARKE 886
Score = 36.7 bits (81), Expect = 0.28
Identities = 27/123 (21%), Positives = 65/123 (52%), Gaps = 11/123 (8%)
Query: 521 ESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYD----- 575
E +++ EEL +K + Q + + D+ + +++ D+L + KR E+ +
Sbjct: 676 EGELRKNLEELFQVKMEREQHQT-----EIRDLQDQLSEMHDEL-DSAKRSEDREKGALI 729
Query: 576 EKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADI 635
E+L + +++ L+ + EQE +L K+E+E+ L +E ++ + +KL+ + +A++
Sbjct: 730 EELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAEL 789
Query: 636 DVI 638
+
Sbjct: 790 QAL 792
>AY274808-1|AAP42073.1| 1302|Homo sapiens KIAA1749 protein protein.
Length = 1302
Score = 61.3 bits (142), Expect = 1e-08
Identities = 72/364 (19%), Positives = 152/364 (41%), Gaps = 25/364 (6%)
Query: 273 SIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQEL 332
S ++ RL +E +L+ N+E + Q++ EQ ++E L+ + D+E
Sbjct: 666 STLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREK 725
Query: 333 NKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMN----LN 388
L + + L+D+ +A+E+ + + + + EM+
Sbjct: 726 GALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQY 785
Query: 389 IAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEK-----ESILET 443
A+L + + ++ + + L + D +E+RVK L++E +EK E +
Sbjct: 786 DAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVK-LLQEENEKLQGRSEELERR 844
Query: 444 KQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI----DELKSKLSTEKAIKDIXXXX 499
+Q+++E K D K +++Y+ + + E + E K +S +A+++
Sbjct: 845 VAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALEN-ELEA 903
Query: 500 XXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLR-EFG-AFDNL-NDVGNM 556
ES+ K E+L LKN++ R G + L ++ ++
Sbjct: 904 AQGNLSQTTQEQKQLSEKLKEESEQK---EQLRRLKNEMENERWHLGKTIEKLQKEMADI 960
Query: 557 INQQRDKLFELTKRQEEYDEKLQTKENEIKR-LVESMTEQEH---VLNKKEKEIKMLNEK 612
+ R EL + +EY EK + + E++R L E E E K + E++++ E+
Sbjct: 961 VEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEE 1020
Query: 613 EEEH 616
++
Sbjct: 1021 LRDY 1024
Score = 50.8 bits (116), Expect = 2e-05
Identities = 98/540 (18%), Positives = 213/540 (39%), Gaps = 43/540 (7%)
Query: 144 EETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEIND 203
E+ L KR+ + + + +E + + ++++AE L+ S++ E K +
Sbjct: 750 EDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVE----EATKNVEV 805
Query: 204 IIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXX 263
+ + + ++R K L L ++ E+ +++ +
Sbjct: 806 LASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKET 865
Query: 264 XXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXX 323
+ ++ L A + K V LE LE A+ +L +T
Sbjct: 866 LKKYEGEIRQL-EEALVHARKEEKEAVSARRALENELEAAQG---NLSQTTQEQKQLSEK 921
Query: 324 XXEDFDQ--ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDM 381
E+ +Q +L +L +++ HL EKLQ + + +
Sbjct: 922 LKEESEQKEQLRRLKNEMENERWHLGKTI---EKLQKEMADIVEASRTSTLELQNQLDEY 978
Query: 382 KHEMNLNIAKLI-EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESI 440
K + +A++ ++++K ++ + + T + D++R L+E ELR D R DE
Sbjct: 979 KEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMR--LMEEELR--DYQRAQDEA--- 1031
Query: 441 LETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXX 500
L +Q +++ L+ + +LE + ++ RL+ + +++ +L+ +L E+ D+
Sbjct: 1032 LTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERI 1091
Query: 501 XXXXXXXXXXXXXXXXXXXRESQMK----SYYEELMNLKNQITQLREFGAFDNLNDVGNM 556
++ S + +LK++I L G++ + + +
Sbjct: 1092 SRSREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLE--GSYRSSKE--GL 1147
Query: 557 INQQRDKLFELTKR--QEEYDE-KLQTKENEIKRLVE-----------SMTEQEHVLNKK 602
+ Q ++ EL R EE D LQ ++R V+ S+T+Q+ L+ +
Sbjct: 1148 VVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLR 1207
Query: 603 EKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVL 662
K +K E+ EE ++ + KL+ E +D+ L S+ L + ++VL
Sbjct: 1208 LKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPSKVL 1267
Score = 50.4 bits (115), Expect = 2e-05
Identities = 63/265 (23%), Positives = 115/265 (43%), Gaps = 25/265 (9%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD 435
K+ +++K E A L E+ ++N+ +EE TLQ+ +++ E ELR + L+
Sbjct: 635 KNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEE-----SEGELR-----KNLE 684
Query: 436 EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLL-FEKGEEIDELKSKLSTEKAIKD 494
E + ++ Q E+ + L E++ KR EKG I+EL L ++ ++D
Sbjct: 685 ELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEEL---LQAKQDLQD 741
Query: 495 IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQ----ITQLREF--GAFD 548
+ + ++ S+ +E+ LK Q + LRE A
Sbjct: 742 LLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATK 801
Query: 549 NLNDVGNMIN--QQRDKLFEL-TKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKE 605
N+ + + N +Q E+ K +E +EKLQ + E++R V + Q L E +
Sbjct: 802 NVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAK 861
Query: 606 IKMLNEKEEEHMNIIN--LLHNKLE 628
K +K E + + L+H + E
Sbjct: 862 AKETLKKYEGEIRQLEEALVHARKE 886
Score = 36.7 bits (81), Expect = 0.28
Identities = 27/123 (21%), Positives = 65/123 (52%), Gaps = 11/123 (8%)
Query: 521 ESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYD----- 575
E +++ EEL +K + Q + + D+ + +++ D+L + KR E+ +
Sbjct: 676 EGELRKNLEELFQVKMEREQHQT-----EIRDLQDQLSEMHDEL-DSAKRSEDREKGALI 729
Query: 576 EKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADI 635
E+L + +++ L+ + EQE +L K+E+E+ L +E ++ + +KL+ + +A++
Sbjct: 730 EELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAEL 789
Query: 636 DVI 638
+
Sbjct: 790 QAL 792
>AB051536-1|BAB21840.2| 1047|Homo sapiens KIAA1749 protein protein.
Length = 1047
Score = 61.3 bits (142), Expect = 1e-08
Identities = 72/364 (19%), Positives = 152/364 (41%), Gaps = 25/364 (6%)
Query: 273 SIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQEL 332
S ++ RL +E +L+ N+E + Q++ EQ ++E L+ + D+E
Sbjct: 411 STLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREK 470
Query: 333 NKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMN----LN 388
L + + L+D+ +A+E+ + + + + EM+
Sbjct: 471 GALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQY 530
Query: 389 IAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEK-----ESILET 443
A+L + + ++ + + L + D +E+RVK L++E +EK E +
Sbjct: 531 DAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVK-LLQEENEKLQGRSEELERR 589
Query: 444 KQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI----DELKSKLSTEKAIKDIXXXX 499
+Q+++E K D K +++Y+ + + E + E K +S +A+++
Sbjct: 590 VAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALEN-ELEA 648
Query: 500 XXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLR-EFG-AFDNL-NDVGNM 556
ES+ K E+L LKN++ R G + L ++ ++
Sbjct: 649 AQGNLSQTTQEQKQLSEKLKEESEQK---EQLRRLKNEMENERWHLGKTIEKLQKEMADI 705
Query: 557 INQQRDKLFELTKRQEEYDEKLQTKENEIKR-LVESMTEQEH---VLNKKEKEIKMLNEK 612
+ R EL + +EY EK + + E++R L E E E K + E++++ E+
Sbjct: 706 VEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEE 765
Query: 613 EEEH 616
++
Sbjct: 766 LRDY 769
Score = 50.8 bits (116), Expect = 2e-05
Identities = 98/540 (18%), Positives = 213/540 (39%), Gaps = 43/540 (7%)
Query: 144 EETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEIND 203
E+ L KR+ + + + +E + + ++++AE L+ S++ E K +
Sbjct: 495 EDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVE----EATKNVEV 550
Query: 204 IIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXX 263
+ + + ++R K L L ++ E+ +++ +
Sbjct: 551 LASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKET 610
Query: 264 XXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXX 323
+ ++ L A + K V LE LE A+ +L +T
Sbjct: 611 LKKYEGEIRQL-EEALVHARKEEKEAVSARRALENELEAAQG---NLSQTTQEQKQLSEK 666
Query: 324 XXEDFDQ--ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDM 381
E+ +Q +L +L +++ HL EKLQ + + +
Sbjct: 667 LKEESEQKEQLRRLKNEMENERWHLGKTI---EKLQKEMADIVEASRTSTLELQNQLDEY 723
Query: 382 KHEMNLNIAKLI-EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESI 440
K + +A++ ++++K ++ + + T + D++R L+E ELR D R DE
Sbjct: 724 KEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMR--LMEEELR--DYQRAQDEA--- 776
Query: 441 LETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXX 500
L +Q +++ L+ + +LE + ++ RL+ + +++ +L+ +L E+ D+
Sbjct: 777 LTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERI 836
Query: 501 XXXXXXXXXXXXXXXXXXXRESQMK----SYYEELMNLKNQITQLREFGAFDNLNDVGNM 556
++ S + +LK++I L G++ + + +
Sbjct: 837 SRSREQMEQVRNELLQERAARQDLECDKISLERQNKDLKSRIIHLE--GSYRSSKE--GL 892
Query: 557 INQQRDKLFELTKR--QEEYDE-KLQTKENEIKRLVE-----------SMTEQEHVLNKK 602
+ Q ++ EL R EE D LQ ++R V+ S+T+Q+ L+ +
Sbjct: 893 VVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLR 952
Query: 603 EKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVL 662
K +K E+ EE ++ + KL+ E +D+ L S+ L + ++VL
Sbjct: 953 LKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPSKVL 1012
Score = 50.4 bits (115), Expect = 2e-05
Identities = 63/265 (23%), Positives = 115/265 (43%), Gaps = 25/265 (9%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD 435
K+ +++K E A L E+ ++N+ +EE TLQ+ +++ E ELR + L+
Sbjct: 380 KNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEE-----SEGELR-----KNLE 429
Query: 436 EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLL-FEKGEEIDELKSKLSTEKAIKD 494
E + ++ Q E+ + L E++ KR EKG I+EL L ++ ++D
Sbjct: 430 ELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEEL---LQAKQDLQD 486
Query: 495 IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQ----ITQLREF--GAFD 548
+ + ++ S+ +E+ LK Q + LRE A
Sbjct: 487 LLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATK 546
Query: 549 NLNDVGNMIN--QQRDKLFEL-TKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKE 605
N+ + + N +Q E+ K +E +EKLQ + E++R V + Q L E +
Sbjct: 547 NVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAK 606
Query: 606 IKMLNEKEEEHMNIIN--LLHNKLE 628
K +K E + + L+H + E
Sbjct: 607 AKETLKKYEGEIRQLEEALVHARKE 631
Score = 36.7 bits (81), Expect = 0.28
Identities = 27/123 (21%), Positives = 65/123 (52%), Gaps = 11/123 (8%)
Query: 521 ESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYD----- 575
E +++ EEL +K + Q + + D+ + +++ D+L + KR E+ +
Sbjct: 421 EGELRKNLEELFQVKMEREQHQT-----EIRDLQDQLSEMHDEL-DSAKRSEDREKGALI 474
Query: 576 EKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADI 635
E+L + +++ L+ + EQE +L K+E+E+ L +E ++ + +KL+ + +A++
Sbjct: 475 EELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAEL 534
Query: 636 DVI 638
+
Sbjct: 535 QAL 537
>AB002334-1|BAA20794.2| 1635|Homo sapiens KIAA0336 protein.
Length = 1635
Score = 60.1 bits (139), Expect = 3e-08
Identities = 129/656 (19%), Positives = 269/656 (41%), Gaps = 73/656 (11%)
Query: 5 ELEIQQNQTDGCLYEDLNEQESITSESHKI-TKLKTVWQEKMVTF--------EKSKKEL 55
ELE + N+ G L E L E++ + K+ ++K + ++K V E +K
Sbjct: 591 ELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSS 650
Query: 56 EDRQ-NQVMELYASLRNT---HRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAG- 110
E +Q ++ +E++ S + + L +K+ L E+ ++ + L EQ+ +L
Sbjct: 651 EKKQLSRDLEVFLSQKEDVILKEHITQLEKKLQLMVEEQDNLNKL--LENEQVQKLFVKT 708
Query: 111 ---GEPKALEHSTLDNKVTFDV-NKLLNIPNSLVDKCEETL---FKRKEIINWFES---L 160
G K + ++ DV N L + SL EE F+R E + E
Sbjct: 709 QLYGFLKEMGSEVSEDSEEKDVVNVLQAVGESLAKINEEKCNLAFQRDEKVLELEKEIKC 768
Query: 161 MSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQ- 219
+ +E + + L ++++ E LL+ L+++++E +D+++ KNANE L+
Sbjct: 769 LQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEM--KNANEKTRLEN 826
Query: 220 ----LRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIM 275
++ +E+S S N + + I ++ +P + ++
Sbjct: 827 QNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELI-------LL 879
Query: 276 KDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKL 335
KD L+++ + V +LE +E E E + ++ D K
Sbjct: 880 KDSLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSS-RKE 938
Query: 336 TQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEI 395
TQ++K+ LE + +++L SAS I+ + NL L+E
Sbjct: 939 TQTVKEE---LESLRSEKDQL--------------SASMRDLIQGAESYKNL----LLEY 977
Query: 396 EKKYNDSIEEKK---TLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELE 452
EK+ EK+ + I+DL L S L+ + + + ++ + +ET Q K LE
Sbjct: 978 EKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLE 1037
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXX 512
+++ K ++ K L EK ++ ++K +T ++++
Sbjct: 1038 VQILEVQRAKAMVD--KELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQE 1095
Query: 513 XXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQE 572
+ Q E+ + + + +L + L + N I ++ ++QE
Sbjct: 1096 LELVKKDAQ-QTTLMNMEIADYERLMKELNQ-----KLTNKNNKIEDLEQEIKIQKQKQE 1149
Query: 573 EYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
E++ + ++ +++ E T+ + +L K +KE+ + E +H+ + L +LE
Sbjct: 1150 TLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGELE 1205
Score = 50.8 bits (116), Expect = 2e-05
Identities = 65/303 (21%), Positives = 132/303 (43%), Gaps = 24/303 (7%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDL----V 431
K ++D + E+ L L + ND + K L+E I++L + E E ++ + V
Sbjct: 867 KELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAV 926
Query: 432 RELDEKESILETKQCVQKELESTKTDLEHRKTEI-------EEYKRLLFE---KGEEIDE 481
+ E +S + Q V++ELES +++ + + E YK LL E + E++D
Sbjct: 927 KAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDV 986
Query: 482 LKSKLST-EKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQ 540
K + + E I+D+ +++++ L+ QI +
Sbjct: 987 EKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLL----ARIETLQSNAKLLEVQILE 1042
Query: 541 LREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLN 600
++ A + + Q+ K+ E E +E + E K+L ++M E E ++
Sbjct: 1043 VQRAKAMVDKELEAEKL-QKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELE-LVK 1100
Query: 601 KKEKEIKMLNEKEEEHMNIINLLHNKLELRNE--ADIDVIITLAKYKKSLTLVLEKMSIS 658
K ++ ++N + ++ ++ L+ KL +N D++ I + K K+ TL E S+
Sbjct: 1101 KDAQQTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQE-TLQEEITSLQ 1159
Query: 659 NRV 661
+ V
Sbjct: 1160 SSV 1162
Score = 48.8 bits (111), Expect = 7e-05
Identities = 60/307 (19%), Positives = 127/307 (41%), Gaps = 15/307 (4%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD 435
K K+ + ++N ++ +K+ + S +E +T++E ++ LR++ + ++DL++ +
Sbjct: 909 KECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAE 968
Query: 436 E-KESILE-TKQCVQKELESTKTD-LEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAI 492
K +LE KQ Q ++E + + EHR IE+ R L + + + S E +
Sbjct: 969 SYKNLLLEYEKQSEQLDVEKERANNFEHR---IEDLTRQLRNSTLQCETINS--DNEDLL 1023
Query: 493 KDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFD-NLN 551
I + ++ +K T + E L
Sbjct: 1024 ARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQ 1083
Query: 552 DVGNMINQQRDKLFELTKRQEEYDEKLQTK----ENEIKRLVESMTEQEHVLNKKEKEIK 607
+ + +L EL K+ + + + E +K L + +T + + + E+EIK
Sbjct: 1084 KEKKQLQKTMQEL-ELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIK 1142
Query: 608 MLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVLKCSLL 667
+ +K+E I L + ++ E + + L K KK L ++ + +L+ SL
Sbjct: 1143 IQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELA-DSKQAETDHLILQASLK 1201
Query: 668 GVVTQSR 674
G + S+
Sbjct: 1202 GELEASQ 1208
Score = 32.3 bits (70), Expect = 6.1
Identities = 28/122 (22%), Positives = 58/122 (47%), Gaps = 2/122 (1%)
Query: 373 SYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVR 432
+Y K I+++K+E+ +K E + +EE Q + + SE VK L
Sbjct: 77 NYVKEIENLKNELMAVRSKYSEDKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVKKLQE 136
Query: 433 ELDE-KESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEE-IDELKSKLSTEK 490
E+++ + E +QK+L++T + + T+++ + ++ I+ L+ +L K
Sbjct: 137 EIEKIRPGFEEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLK 196
Query: 491 AI 492
AI
Sbjct: 197 AI 198
>BC011621-1|AAH11621.1| 728|Homo sapiens hook homolog 1
(Drosophila) protein.
Length = 728
Score = 59.7 bits (138), Expect = 3e-08
Identities = 127/631 (20%), Positives = 241/631 (38%), Gaps = 48/631 (7%)
Query: 60 NQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHS 119
NQ+ E + +LG +N +E HI N+ L E + + + +
Sbjct: 106 NQITECSDPVELGRLLQLILGCAINCEKKQE-HIQNIMTLE-ESVQHVVMTAIQELMSKE 163
Query: 120 TLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEF 179
L + V +L +++ +E L +++E+ E L Q TL +
Sbjct: 164 ILSSPPNDAVGELEQQLKRALEELQEALAEKEELRQRCEELDMQ-----VTTLQDEKNSL 218
Query: 180 NAENDLLKSSLDQLRTEFLKEINDIIDCLRKNAN-ETMALQLRTKELSCALSDLNTQNAE 238
+EN+++ LDQL F + N ++ +A + LQ L A D E
Sbjct: 219 VSENEMMNEKLDQLDGSF-DDPNTVVAKKYFHAQLQLEQLQEENFRLEAAKDDYRVHCEE 277
Query: 239 MRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEA 298
+ KQ+ H RN + S ++L++ VE Q
Sbjct: 278 LEKQLIEFQH------RNDELTSLAEETRALKDEIDVLRATSDKANKLESTVEIYRQKLQ 331
Query: 299 ALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQS 358
L R + +L+ T ++EL K + T+ + KL S
Sbjct: 332 DLNDLRKQVKTLQET----NMMYMHNTVSLEEELKKANAARTQLETYKRQVQDLHVKLSS 387
Query: 359 XXXXXXXXXXXXSASYNKSIKDMKHEMNL-NIAKLIEIEKKYNDSIEEKKTLQENIDDLR 417
+ ++ + KHE L +LIE ++ EE + Q D L
Sbjct: 388 ------ESKRADTLAFEMKRLEEKHEALLKEKERLIEQRDTLKETNEELRCSQVQQDHLN 441
Query: 418 TDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTE-IEEYKRLLFEKG 476
+ ++L E+ E E +Q E + + E + E IEE + L +K
Sbjct: 442 QTDASATKSYENLAAEIMPVE-YREVFIRLQHENKMLRLQQEGSENERIEELQEQLEQKH 500
Query: 477 EEIDELKS--KLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXR-ESQMKSYYEELMN 533
+++EL++ +LS E+ I+++ + + +++++ E+L
Sbjct: 501 RKMNELETEQRLSKER-IRELQQQIEDLQKSLQEQGSKSEGESSSKLKQKLEAHMEKLTE 559
Query: 534 LKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVES-- 591
+ ++ + +E + D+ INQ K+ EL ++ DE ++ E K +E
Sbjct: 560 VHEELQKKQEL-----IEDLQPDINQNVQKINELEAALQKKDEDMKAMEERYKMYLEKAR 614
Query: 592 --MTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADI-DVIITLAKYKKSL 648
+ + LN EI +L ++ E I +L ++ ++ D + +I A Y KS
Sbjct: 615 NVIKTLDPKLNPASAEIMLLRKQLAEKERRIEILESECKVAKFRDYEEKLIVSAWYNKS- 673
Query: 649 TLVLEKMSISNRVLK----CSLLGVVTQSRT 675
L +K+ + +R++ CS G T +R+
Sbjct: 674 -LAFQKLGMESRLVSGGGACSDTGACTPARS 703
>AL035416-6|CAI22779.1| 728|Homo sapiens hook homolog 1
(Drosophila) protein.
Length = 728
Score = 59.7 bits (138), Expect = 3e-08
Identities = 127/631 (20%), Positives = 241/631 (38%), Gaps = 48/631 (7%)
Query: 60 NQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHS 119
NQ+ E + +LG +N +E HI N+ L E + + + +
Sbjct: 106 NQITECSDPVELGRLLQLILGCAINCEKKQE-HIQNIMTLE-ESVQHVVMTAIQELMSKE 163
Query: 120 TLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEF 179
L + V +L +++ +E L +++E+ E L Q TL +
Sbjct: 164 ILSSPPNDAVGELEQQLKRALEELQEALAEKEELRQRCEELDMQ-----VTTLQDEKNSL 218
Query: 180 NAENDLLKSSLDQLRTEFLKEINDIIDCLRKNAN-ETMALQLRTKELSCALSDLNTQNAE 238
+EN+++ LDQL F + N ++ +A + LQ L A D E
Sbjct: 219 VSENEMMNEKLDQLDGSF-DDPNTVVAKKYFHAQLQLEQLQEENFRLEAAKDDYRVHCEE 277
Query: 239 MRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEA 298
+ KQ+ H RN + S ++L++ VE Q
Sbjct: 278 LEKQLIEFQH------RNDELTSLAEETRALKDEIDVLRATSDKANKLESTVEIYRQKLQ 331
Query: 299 ALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQS 358
L R + +L+ T ++EL K + T+ + KL S
Sbjct: 332 DLNDLRKQVKTLQET----NMMYMHNTVSLEEELKKANAARTQLETYKRQVQDLHVKLSS 387
Query: 359 XXXXXXXXXXXXSASYNKSIKDMKHEMNL-NIAKLIEIEKKYNDSIEEKKTLQENIDDLR 417
+ ++ + KHE L +LIE ++ EE + Q D L
Sbjct: 388 ------ESKRADTLAFEMKRLEEKHEALLKEKERLIEQRDTLKETNEELRCSQVQQDHLN 441
Query: 418 TDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTE-IEEYKRLLFEKG 476
+ ++L E+ E E +Q E + + E + E IEE + L +K
Sbjct: 442 QTDASATKSYENLAAEIMPVE-YREVFIRLQHENKMLRLQQEGSENERIEELQEQLEQKH 500
Query: 477 EEIDELKS--KLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXR-ESQMKSYYEELMN 533
+++EL++ +LS E+ I+++ + + +++++ E+L
Sbjct: 501 RKMNELETEQRLSKER-IRELQQQIEDLQKSLQEQGSKSEGESSSKLKQKLEAHMEKLTE 559
Query: 534 LKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVES-- 591
+ ++ + +E + D+ INQ K+ EL ++ DE ++ E K +E
Sbjct: 560 VHEELQKKQEL-----IEDLQPDINQNVQKINELEAALQKKDEDMKAMEERYKMYLEKAR 614
Query: 592 --MTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADI-DVIITLAKYKKSL 648
+ + LN EI +L ++ E I +L ++ ++ D + +I A Y KS
Sbjct: 615 NVIKTLDPKLNPASAEIMLLRKQLAEKERRIEILESECKVAKFRDYEEKLIVSAWYNKS- 673
Query: 649 TLVLEKMSISNRVLK----CSLLGVVTQSRT 675
L +K+ + +R++ CS G T +R+
Sbjct: 674 -LAFQKLGMESRLVSGGGACSDTGACTPARS 703
>AF044923-1|AAC09298.1| 728|Homo sapiens hook1 protein protein.
Length = 728
Score = 59.7 bits (138), Expect = 3e-08
Identities = 127/631 (20%), Positives = 241/631 (38%), Gaps = 48/631 (7%)
Query: 60 NQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHS 119
NQ+ E + +LG +N +E HI N+ L E + + + +
Sbjct: 106 NQITECSDPVELGRLLQLILGCAINCEKKQE-HIQNIMTLE-ESVQHVVMTAIQELMSKE 163
Query: 120 TLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEF 179
L + V +L +++ +E L +++E+ E L Q TL +
Sbjct: 164 ILSSPPNDAVGELEQQLKRALEELQEALAEKEELRQRCEELDMQ-----VTTLQDEKNSL 218
Query: 180 NAENDLLKSSLDQLRTEFLKEINDIIDCLRKNAN-ETMALQLRTKELSCALSDLNTQNAE 238
+EN+++ LDQL F + N ++ +A + LQ L A D E
Sbjct: 219 VSENEMMNEKLDQLDGSF-DDPNTVVAKKYFHAQLQLEQLQEENFRLEAAKDDYRVHCEE 277
Query: 239 MRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEA 298
+ KQ+ H RN + S ++L++ VE Q
Sbjct: 278 LEKQLIEFQH------RNDELTSLAEETRALKDEIDVLRATSDKANKLESTVEIYRQKLQ 331
Query: 299 ALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQS 358
L R + +L+ T ++EL K + T+ + KL S
Sbjct: 332 DLNDLRKQVKTLQET----NMMYMHNTVSLEEELKKANAARTQLETYKRQVQDLHVKLSS 387
Query: 359 XXXXXXXXXXXXSASYNKSIKDMKHEMNL-NIAKLIEIEKKYNDSIEEKKTLQENIDDLR 417
+ ++ + KHE L +LIE ++ EE + Q D L
Sbjct: 388 ------ESKRADTLAFEMKRLEEKHEALLKEKERLIEQRDTLKETNEELRCSQVQQDHLN 441
Query: 418 TDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTE-IEEYKRLLFEKG 476
+ ++L E+ E E +Q E + + E + E IEE + L +K
Sbjct: 442 QTDASATKSYENLAAEIMPVE-YREVFIRLQHENKMLRLQQEGSENERIEELQEQLEQKH 500
Query: 477 EEIDELKS--KLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXR-ESQMKSYYEELMN 533
+++EL++ +LS E+ I+++ + + +++++ E+L
Sbjct: 501 RKMNELETEQRLSKER-IRELQQQIEDLQKSLQEQGSKSEGESSSKLKQKLEAHMEKLTE 559
Query: 534 LKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVES-- 591
+ ++ + +E + D+ INQ K+ EL ++ DE ++ E K +E
Sbjct: 560 VHEELQKKQEL-----IEDLQPDINQNVQKINELEAALQKKDEDMKAMEERYKMYLEKAR 614
Query: 592 --MTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADI-DVIITLAKYKKSL 648
+ + LN EI +L ++ E I +L ++ ++ D + +I A Y KS
Sbjct: 615 NVIKTLDPKLNPASAEIMLLRKQLAEKERRIEILESECKVAKFRDYEEKLIVSAWYNKS- 673
Query: 649 TLVLEKMSISNRVLK----CSLLGVVTQSRT 675
L +K+ + +R++ CS G T +R+
Sbjct: 674 -LAFQKLGMESRLVSGGGACSDTGACTPARS 703
>M77830-1|AAA85135.1| 2871|Homo sapiens desmoplakin I protein.
Length = 2871
Score = 59.3 bits (137), Expect = 5e-08
Identities = 74/321 (23%), Positives = 136/321 (42%), Gaps = 32/321 (9%)
Query: 375 NKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVREL 434
N+ +KD +N +I + E ++ ++ ++K I + L E+ +K ++++
Sbjct: 1246 NRDLKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHL---EIELKQVMQQR 1302
Query: 435 DE-----KESILETKQCVQ---KELESTKTDLEH---RKTEIE-EYKRLLFEKGEEIDEL 482
E K+S+ E + +Q KE+E K + + R+ E E E ++ EEI L
Sbjct: 1303 SEDNARHKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISL 1362
Query: 483 KSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLR 542
K++ TE I RE+ +S EE+ LKN +TQ
Sbjct: 1363 KNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTREN--RSLSEEIKRLKNTLTQTT 1420
Query: 543 EFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKL----QTKENEIKRLVESMTEQEHV 598
E NL V I QQ+ E+++R+++ + +L Q + E R +S+ +
Sbjct: 1421 E-----NLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKT 1475
Query: 599 LNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSIS 658
+ K KEI+ L + ++ N L ++ D L K S T + K+ +
Sbjct: 1476 IQDKNKEIERLKQLIDKETNDRKCLEDENARLQRVQYD----LQKANSSATETINKLKVQ 1531
Query: 659 NRVLKCSLLGV--VTQSRTLR 677
+ L + V+Q RT++
Sbjct: 1532 EQELTRLRIDYERVSQERTVK 1552
Score = 38.3 bits (85), Expect = 0.092
Identities = 54/281 (19%), Positives = 118/281 (41%), Gaps = 25/281 (8%)
Query: 374 YNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRE 433
+ S+K+++ + +L +++ ++ ++K L+E ++ +R L E +++ +L ++
Sbjct: 1559 FQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQ 1618
Query: 434 LDE-------KESILETKQCV----QKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDEL 482
L++ E L ++ V +E + T+ +L +E+E +R L ++ E + +
Sbjct: 1619 LEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQA 1678
Query: 483 KSKLS-TEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQL 541
+ +KAI+D +E M EEL NL+ + L
Sbjct: 1679 HLRNEHFQKAIED--KSRSLNESKIEIERLQSLTENLTKEHLMLE--EELRNLRLEYDDL 1734
Query: 542 REFGAFDNLNDVGNMINQQRDKLFELTKRQEEYD---EKLQTKENEIKRLVESMTEQ--- 595
R G + +D I + R +L R E LQ + +++ +E +Q
Sbjct: 1735 RR-GRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQALE 1793
Query: 596 --EHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEAD 634
+ K + +++ E+E + I L +K L+ D
Sbjct: 1794 ASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLED 1834
Score = 35.5 bits (78), Expect = 0.65
Identities = 35/167 (20%), Positives = 74/167 (44%), Gaps = 9/167 (5%)
Query: 522 SQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELT-------KRQEEY 574
SQ K+ L LK Q +L A NL+ I + +K+ LT +R++
Sbjct: 1070 SQFKAKLASLEELKRQ-AELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSV 1128
Query: 575 DEKLQTKENEIKRLVES-MTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEA 633
+++ ++N+ +L ++ E+E++ +K + K + EKE E + LL + + E
Sbjct: 1129 EDRFDQQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQEEGTRKREY 1188
Query: 634 DIDVIITLAKYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRTLRKNM 680
+ ++ Y + ++ + K + K ++ + Q KN+
Sbjct: 1189 ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNL 1235
Score = 34.7 bits (76), Expect = 1.1
Identities = 48/290 (16%), Positives = 121/290 (41%), Gaps = 16/290 (5%)
Query: 346 LEDIALAREKLQSXXXXXXXXXXXXSASYNKS------IKDMKHEMNLNIAKLIEIEKKY 399
LED+ L K++ S + NK+ ++ + E + AKL +E+
Sbjct: 1024 LEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFKAKLASLEELK 1083
Query: 400 NDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLE 459
+ + K+ ++N+D + E ++ L E+++++ ++ V+ + K D +
Sbjct: 1084 RQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEK---RRRKSVEDRFDQQKNDYD 1140
Query: 460 H-RKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXX 518
+K E + L ++K E +K K + ++ +
Sbjct: 1141 QLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQEEGTRKREYENELAKVRNHYN 1200
Query: 519 XRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKL 578
S +++ YE +N+ T ++E + +D N+ N Q D+L + ++ DE +
Sbjct: 1201 EEMSNLRNKYETEINITK--TTIKEI-SMQKEDDSKNLRN-QLDRLSR--ENRDLKDEIV 1254
Query: 579 QTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
+ ++ ++ + +E+ L +K +++ +K+ + + ++ + E
Sbjct: 1255 RLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSE 1304
Score = 32.7 bits (71), Expect = 4.6
Identities = 31/139 (22%), Positives = 63/139 (45%), Gaps = 23/139 (16%)
Query: 374 YNKSIKDM--KHEMNLNIAK--LIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKD 429
YN+ + ++ K+E +NI K + EI + D + + + + DL + +R+ D
Sbjct: 1199 YNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLND 1258
Query: 430 LVRELDEK-----ESILETKQC----VQKE----------LESTKTDLEHRKTEIEEYKR 470
+ + E+ E+ L+ K C +QK+ ++ D K +EE +
Sbjct: 1259 SILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNARHKQSLEEAAK 1318
Query: 471 LLFEKGEEIDELKSKLSTE 489
+ +K +EI+ LK++ E
Sbjct: 1319 TIQDKNKEIERLKAEFQEE 1337
>J05211-1|AAA35766.1| 1752|Homo sapiens protein ( Human desmoplakin
mRNA, 3' end. ).
Length = 1752
Score = 59.3 bits (137), Expect = 5e-08
Identities = 74/321 (23%), Positives = 136/321 (42%), Gaps = 32/321 (9%)
Query: 375 NKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVREL 434
N+ +KD +N +I + E ++ ++ ++K I + L E+ +K ++++
Sbjct: 127 NRDLKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHL---EIELKQVMQQR 183
Query: 435 DE-----KESILETKQCVQ---KELESTKTDLEH---RKTEIE-EYKRLLFEKGEEIDEL 482
E K+S+ E + +Q KE+E K + + R+ E E E ++ EEI L
Sbjct: 184 SEDNARHKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISL 243
Query: 483 KSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLR 542
K++ TE I RE+ +S EE+ LKN +TQ
Sbjct: 244 KNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTREN--RSLSEEIKRLKNTLTQTT 301
Query: 543 EFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKL----QTKENEIKRLVESMTEQEHV 598
E NL V I QQ+ E+++R+++ + +L Q + E R +S+ +
Sbjct: 302 E-----NLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKT 356
Query: 599 LNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSIS 658
+ K KEI+ L + ++ N L ++ D L K S T + K+ +
Sbjct: 357 IQDKNKEIERLKQLIDKETNDRKCLEDENARLQRVQYD----LQKANSSATETINKLKVQ 412
Query: 659 NRVLKCSLLGV--VTQSRTLR 677
+ L + V+Q RT++
Sbjct: 413 EQELTRLRIDYERVSQERTVK 433
Score = 38.3 bits (85), Expect = 0.092
Identities = 54/281 (19%), Positives = 118/281 (41%), Gaps = 25/281 (8%)
Query: 374 YNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRE 433
+ S+K+++ + +L +++ ++ ++K L+E ++ +R L E +++ +L ++
Sbjct: 440 FQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQ 499
Query: 434 LDE-------KESILETKQCV----QKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDEL 482
L++ E L ++ V +E + T+ +L +E+E +R L ++ E + +
Sbjct: 500 LEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQA 559
Query: 483 KSKLS-TEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQL 541
+ +KAI+D +E M EEL NL+ + L
Sbjct: 560 HLRNEHFQKAIED--KSRSLNESKIEIERLQSLTENLTKEHLMLE--EELRNLRLEYDDL 615
Query: 542 REFGAFDNLNDVGNMINQQRDKLFELTKRQEEYD---EKLQTKENEIKRLVESMTEQ--- 595
R G + +D I + R +L R E LQ + +++ +E +Q
Sbjct: 616 RR-GRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQALE 674
Query: 596 --EHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEAD 634
+ K + +++ E+E + I L +K L+ D
Sbjct: 675 ASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLED 715
Score = 32.7 bits (71), Expect = 4.6
Identities = 31/139 (22%), Positives = 63/139 (45%), Gaps = 23/139 (16%)
Query: 374 YNKSIKDM--KHEMNLNIAK--LIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKD 429
YN+ + ++ K+E +NI K + EI + D + + + + DL + +R+ D
Sbjct: 80 YNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLND 139
Query: 430 LVRELDEK-----ESILETKQC----VQKE----------LESTKTDLEHRKTEIEEYKR 470
+ + E+ E+ L+ K C +QK+ ++ D K +EE +
Sbjct: 140 SILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNARHKQSLEEAAK 199
Query: 471 LLFEKGEEIDELKSKLSTE 489
+ +K +EI+ LK++ E
Sbjct: 200 TIQDKNKEIERLKAEFQEE 218
>BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,
non-muscle protein.
Length = 1976
Score = 59.3 bits (137), Expect = 5e-08
Identities = 119/607 (19%), Positives = 235/607 (38%), Gaps = 52/607 (8%)
Query: 17 LYEDLNEQESITSESHKITKLKTVWQEKMVT-FEKSKKELEDRQNQVMELYASLRNTHRK 75
L E L++ ES E + ++ ++KM + +++L++ + +L K
Sbjct: 920 LEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAK 979
Query: 76 MKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNI 135
+K + +++ L + + KL +++ + C+ A E N + K+ N
Sbjct: 980 IKKMEEEILLLEDQNSKFIKEKKLMEDRIAE-CSS--QLAEEEEKAKN-----LAKIRNK 1031
Query: 136 PNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRT 195
++ EE L K ++ E + G T L +I E A+ +D+L+
Sbjct: 1032 QEVMISDLEERLKKEEKTRQELEKAKRKLDG-ETTDLQDQIAELQAQ-------IDELKL 1083
Query: 196 EFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANR 255
+ K+ ++ L + +ET+ K + +L Q AE+++ S R A +
Sbjct: 1084 QLAKKEEELQGALARGDDETLHKNNALK----VVRELQAQIAELQEDFESEKASRNKAEK 1139
Query: 256 NXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVER-VVQLEAALEQARSESWSLERTV 314
+ + A+ +L+T E+ V +L+ ALE+ E+ + E +
Sbjct: 1140 QKRDLSEELEALKTELEDTLDT--TAAQQELRTKREQEVAELKKALEE---ETKNHEAQI 1194
Query: 315 XXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASY 374
E+ ++L + + K N + K + S
Sbjct: 1195 QDMRQRHATALEELSEQLEQ-AKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHK 1253
Query: 375 NKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVREL 434
K + E++ AK+ E ++ + E+ LQ +D++ T L E+E + ++
Sbjct: 1254 RKKLDAQVQELH---AKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDA 1310
Query: 435 DEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE-----------LK 483
ES L+ Q + +E K +L R ++EE K L E+ EE +E L+
Sbjct: 1311 ASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQ 1370
Query: 484 SKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLRE 543
S+L+ K D R + Y++L KN++ Q
Sbjct: 1371 SQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQ--- 1427
Query: 544 FGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKE 603
+D+ ++ QR L K+Q+++D+ L +++ R E E +E
Sbjct: 1428 -----EPDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAE--AEARE 1480
Query: 604 KEIKMLN 610
KE K L+
Sbjct: 1481 KETKALS 1487
Score = 46.0 bits (104), Expect = 5e-04
Identities = 59/300 (19%), Positives = 129/300 (43%), Gaps = 19/300 (6%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD 435
K++ ++++ + I+ L E KK + +E + + +D TDL + ++ +L ++D
Sbjct: 1023 KNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQD---QIAELQAQID 1079
Query: 436 E-KESILETKQCVQKELESTKTDLEHRKTEIEEYKRL---LFEKGEEIDELK-SKLSTEK 490
E K + + ++ +Q L + H+ ++ + L + E E+ + K S+ EK
Sbjct: 1080 ELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEK 1139
Query: 491 AIKDIXXXXXXXXXXXXXXXXXXXXXX---XXRESQM----KSYYEELMNLKNQITQLRE 543
+D+ RE ++ K+ EE N + QI +R+
Sbjct: 1140 QKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQ 1199
Query: 544 FGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKE 603
A L ++ + Q + L K ++ + + E+K L + E EH K +
Sbjct: 1200 RHA-TALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLD 1258
Query: 604 KEIKMLNEKEEEHMNI-INLLHNKLELRNEAD-IDVIITLAKYKKSLTLVLEKMSISNRV 661
+++ L+ K E + + L +L+NE D + ++ A+ KK + + S+ +++
Sbjct: 1259 AQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAE-KKGIKFAKDAASLESQL 1317
Score = 41.5 bits (93), Expect = 0.010
Identities = 47/226 (20%), Positives = 93/226 (41%), Gaps = 9/226 (3%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKE 450
+L E+E+K+ +EEK L E + E+E L + E E IL + +E
Sbjct: 874 ELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEE 933
Query: 451 LESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXX 510
E L++ K +++ + + L E+ +E + + KL EK +
Sbjct: 934 EEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEK----VTAEAKIKKMEEEILL 989
Query: 511 XXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKR 570
+E ++ + + +Q+ + E NL + N L E K+
Sbjct: 990 LEDQNSKFIKEKKLME--DRIAECSSQLAEEEE--KAKNLAKIRNKQEVMISDLEERLKK 1045
Query: 571 QEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM-LNEKEEE 615
+E+ ++L+ + ++ + +Q L + E+K+ L +KEEE
Sbjct: 1046 EEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEE 1091
Score = 37.5 bits (83), Expect = 0.16
Identities = 44/182 (24%), Positives = 84/182 (46%), Gaps = 24/182 (13%)
Query: 326 EDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEM 385
E ++ KL + + + LE+ ALA +KL+ + D+ H+
Sbjct: 1388 ESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQEPDDLTV-------DLDHQR 1440
Query: 386 NLNIAKLIEIEKKYNDSIEEKKTLQ----ENIDDLRTDLLESELRVKDLVRELDE----K 437
+ + L + +KK++ + E+K++ E D + E E + L R L+E K
Sbjct: 1441 QV-ASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAK 1499
Query: 438 ESILETKQCVQKELE---STKTDLEHRKTEIEEYKRLLFEKGEE----IDELKSKL-STE 489
E + ++ ++E S+K D+ E+E+ KR L ++ EE ++EL+ +L +TE
Sbjct: 1500 EEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATE 1559
Query: 490 KA 491
A
Sbjct: 1560 DA 1561
Score = 35.9 bits (79), Expect = 0.49
Identities = 55/318 (17%), Positives = 123/318 (38%), Gaps = 17/318 (5%)
Query: 167 ISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELS 226
I K L +I+ N D + L +L+ + +K+ ++ R + +E A ++KE
Sbjct: 1624 IDLKDLEAQIEAANKARDEVIKQLRKLQAQ-MKDYQRELEEARASRDEIFA---QSKESE 1679
Query: 227 CALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIM--KDRLSRAEH 284
L L + ++++++ S + R +A + +++ K RL
Sbjct: 1680 KKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIA 1739
Query: 285 QLKTNVERVVQ-LEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNT 343
QL+ +E +E ++ R + ++ T+ + D +L + K+
Sbjct: 1740 QLEEELEEEQSNMELLNDRFRKTTLQVD-TLNAELAAERSAAQKSDNARQQLERQNKELK 1798
Query: 344 THLEDIALA-REKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDS 402
L+++ A + K ++ + K+ L + EKK +
Sbjct: 1799 AKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKL----VRRTEKKLKEI 1854
Query: 403 IEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKES----ILETKQCVQKELESTKTDL 458
+ + + + D + + ++ R+K L R+L+E E +++ +Q+EL+
Sbjct: 1855 FMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEAN 1914
Query: 459 EHRKTEIEEYKRLLFEKG 476
E E+ K L G
Sbjct: 1915 EGLSREVSTLKNRLRRGG 1932
Score = 34.7 bits (76), Expect = 1.1
Identities = 55/284 (19%), Positives = 121/284 (42%), Gaps = 30/284 (10%)
Query: 374 YNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRE 433
+ + K ++ +M ++ ++ K ++ + K+ L++ ++++RT L E E +L
Sbjct: 1502 FERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELE---DELQAT 1558
Query: 434 LDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI-----DELKSK--- 485
D K + Q ++ + E DL+ R + EE KRLL ++ E+ DE K +
Sbjct: 1559 EDAKLRLEVNMQAMKAQFER---DLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALA 1615
Query: 486 LSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQL--RE 543
++++K ++ ++QMK Y EL + ++ +
Sbjct: 1616 VASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQS 1675
Query: 544 FGAFDNLNDVGNMINQQRDKLF--ELTKR--QEEYDEKLQTKEN----------EIKRLV 589
+ L + I Q +++L E +R ++E DE N E +RL
Sbjct: 1676 KESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLE 1735
Query: 590 ESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEA 633
+ + E L +++ +++LN++ + ++ L+ +L A
Sbjct: 1736 ARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSA 1779
Score = 33.5 bits (73), Expect = 2.6
Identities = 76/448 (16%), Positives = 158/448 (35%), Gaps = 21/448 (4%)
Query: 50 KSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCA 109
K + L R + Y L T +++ + + + + + + ++ QL A
Sbjct: 1399 KDAEALSQRLEEKALAYDKLEKTKNRLQQEPDDLTVDLDHQRQVASNLEKKQKKFDQLLA 1458
Query: 110 GGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGI-- 167
+ + ++ ++ + + SL EE L ++E + L + + +
Sbjct: 1459 EEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMS 1518
Query: 168 STKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRK-NANETMALQLRTKELS 226
S + + E L+ ++++RT+ L+E+ D + + +Q +
Sbjct: 1519 SKDDVGKNVHELEKSKRALEQQVEEMRTQ-LEELEDELQATEDAKLRLEVNMQAMKAQFE 1577
Query: 227 CALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQL 286
L + QN E ++ + + +KD ++ E
Sbjct: 1578 RDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAAN 1637
Query: 287 KTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHL 346
K E + QL Q + LE E +++L L I L
Sbjct: 1638 KARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKES-EKKLKSLEAEILQLQEEL 1696
Query: 347 EDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEK 406
AR + SAS ++ D K + IA+L E +EE+
Sbjct: 1697 ASSERARRHAEQERDELADEITN-SASGKSALLDEKRRLEARIAQLEE-------ELEEE 1748
Query: 407 KTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIE 466
Q N++ L ++ L+V L EL + S + +++LE +L+ + E+E
Sbjct: 1749 ---QSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELE 1805
Query: 467 -----EYKRLLFEKGEEIDELKSKLSTE 489
++K + +I +L+ +L E
Sbjct: 1806 GAVKSKFKATISALEAKIGQLEEQLEQE 1833
Score = 33.1 bits (72), Expect = 3.5
Identities = 64/334 (19%), Positives = 130/334 (38%), Gaps = 25/334 (7%)
Query: 172 LTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNAN-----ETMALQLRTK--E 224
L +K K+ E +L +++ + L+E N + + L+ E M +L K E
Sbjct: 862 LKVKEKQTKVEGEL--EEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQE 919
Query: 225 LSCALSDLNT--QNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRA 282
L L DL + + E R QI + + A+ + K A
Sbjct: 920 LEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEK---VTA 976
Query: 283 EHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDN 342
E ++K E ++ LE + E +E + E+ + L K+ +
Sbjct: 977 EAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEE-EEKAKNLAKIRNKQEVM 1035
Query: 343 TTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDS 402
+ LE+ EK + + I +++ +++ +L + E++ +
Sbjct: 1036 ISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGA 1095
Query: 403 IE--EKKTLQEN-----IDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTK 455
+ + +TL +N + +L+ + E + +D E + + K+ + +ELE+ K
Sbjct: 1096 LARGDDETLHKNNALKVVRELQAQIAELQ---EDFESEKASRNKAEKQKRDLSEELEALK 1152
Query: 456 TDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
T+LE + L ++ +E+ ELK L E
Sbjct: 1153 TELEDTLDTTAAQQELRTKREQEVAELKKALEEE 1186
>AL031058-1|CAA19927.1| 2871|Homo sapiens desmoplakin protein.
Length = 2871
Score = 59.3 bits (137), Expect = 5e-08
Identities = 74/321 (23%), Positives = 136/321 (42%), Gaps = 32/321 (9%)
Query: 375 NKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVREL 434
N+ +KD +N +I + E ++ ++ ++K I + L E+ +K ++++
Sbjct: 1246 NRDLKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHL---EIELKQVMQQR 1302
Query: 435 DE-----KESILETKQCVQ---KELESTKTDLEH---RKTEIE-EYKRLLFEKGEEIDEL 482
E K+S+ E + +Q KE+E K + + R+ E E E ++ EEI L
Sbjct: 1303 SEDNARHKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISL 1362
Query: 483 KSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLR 542
K++ TE I RE+ +S EE+ LKN +TQ
Sbjct: 1363 KNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTREN--RSLSEEIKRLKNTLTQTT 1420
Query: 543 EFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKL----QTKENEIKRLVESMTEQEHV 598
E NL V I QQ+ E+++R+++ + +L Q + E R +S+ +
Sbjct: 1421 E-----NLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKT 1475
Query: 599 LNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSIS 658
+ K KEI+ L + ++ N L ++ D L K S T + K+ +
Sbjct: 1476 IQDKNKEIERLKQLIDKETNDRKCLEDENARLQRVQYD----LQKANSSATETINKLKVQ 1531
Query: 659 NRVLKCSLLGV--VTQSRTLR 677
+ L + V+Q RT++
Sbjct: 1532 EQELTRLRIDYERVSQERTVK 1552
Score = 38.3 bits (85), Expect = 0.092
Identities = 54/281 (19%), Positives = 118/281 (41%), Gaps = 25/281 (8%)
Query: 374 YNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRE 433
+ S+K+++ + +L +++ ++ ++K L+E ++ +R L E +++ +L ++
Sbjct: 1559 FQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQ 1618
Query: 434 LDE-------KESILETKQCV----QKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDEL 482
L++ E L ++ V +E + T+ +L +E+E +R L ++ E + +
Sbjct: 1619 LEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQA 1678
Query: 483 KSKLS-TEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQL 541
+ +KAI+D +E M EEL NL+ + L
Sbjct: 1679 HLRNEHFQKAIED--KSRSLNESKIEIERLQSLTENLTKEHLMLE--EELRNLRLEYDDL 1734
Query: 542 REFGAFDNLNDVGNMINQQRDKLFELTKRQEEYD---EKLQTKENEIKRLVESMTEQ--- 595
R G + +D I + R +L R E LQ + +++ +E +Q
Sbjct: 1735 RR-GRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQALE 1793
Query: 596 --EHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEAD 634
+ K + +++ E+E + I L +K L+ D
Sbjct: 1794 ASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLED 1834
Score = 35.5 bits (78), Expect = 0.65
Identities = 35/167 (20%), Positives = 74/167 (44%), Gaps = 9/167 (5%)
Query: 522 SQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELT-------KRQEEY 574
SQ K+ L LK Q +L A NL+ I + +K+ LT +R++
Sbjct: 1070 SQFKAKLASLEELKRQ-AELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSV 1128
Query: 575 DEKLQTKENEIKRLVES-MTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEA 633
+++ ++N+ +L ++ E+E++ +K + K + EKE E + LL + + E
Sbjct: 1129 EDRFDQQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQEEGTRKREY 1188
Query: 634 DIDVIITLAKYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRTLRKNM 680
+ ++ Y + ++ + K + K ++ + Q KN+
Sbjct: 1189 ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNL 1235
Score = 34.7 bits (76), Expect = 1.1
Identities = 48/290 (16%), Positives = 121/290 (41%), Gaps = 16/290 (5%)
Query: 346 LEDIALAREKLQSXXXXXXXXXXXXSASYNKS------IKDMKHEMNLNIAKLIEIEKKY 399
LED+ L K++ S + NK+ ++ + E + AKL +E+
Sbjct: 1024 LEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFKAKLASLEELK 1083
Query: 400 NDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLE 459
+ + K+ ++N+D + E ++ L E+++++ ++ V+ + K D +
Sbjct: 1084 RQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEK---RRRKSVEDRFDQQKNDYD 1140
Query: 460 H-RKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXX 518
+K E + L ++K E +K K + ++ +
Sbjct: 1141 QLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQEEGTRKREYENELAKVRNHYN 1200
Query: 519 XRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKL 578
S +++ YE +N+ T ++E + +D N+ N Q D+L + ++ DE +
Sbjct: 1201 EEMSNLRNKYETEINITK--TTIKEI-SMQKEDDSKNLRN-QLDRLSR--ENRDLKDEIV 1254
Query: 579 QTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
+ ++ ++ + +E+ L +K +++ +K+ + + ++ + E
Sbjct: 1255 RLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSE 1304
Score = 32.7 bits (71), Expect = 4.6
Identities = 31/139 (22%), Positives = 63/139 (45%), Gaps = 23/139 (16%)
Query: 374 YNKSIKDM--KHEMNLNIAK--LIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKD 429
YN+ + ++ K+E +NI K + EI + D + + + + DL + +R+ D
Sbjct: 1199 YNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLND 1258
Query: 430 LVRELDEK-----ESILETKQC----VQKE----------LESTKTDLEHRKTEIEEYKR 470
+ + E+ E+ L+ K C +QK+ ++ D K +EE +
Sbjct: 1259 SILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNARHKQSLEEAAK 1318
Query: 471 LLFEKGEEIDELKSKLSTE 489
+ +K +EI+ LK++ E
Sbjct: 1319 TIQDKNKEIERLKAEFQEE 1337
>AY610514-1|AAT37906.1| 1302|Homo sapiens paracingulin protein.
Length = 1302
Score = 58.4 bits (135), Expect = 8e-08
Identities = 71/360 (19%), Positives = 149/360 (41%), Gaps = 24/360 (6%)
Query: 273 SIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQEL 332
S ++ RL +E +L+ N+E + Q++ EQ ++E L+ + D+E
Sbjct: 666 STLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREK 725
Query: 333 NKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMN----LN 388
L + + L+D+ +A+E + + + + EM+
Sbjct: 726 GALIEELLQAKQDLQDLLIAKEGREDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQY 785
Query: 389 IAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEK-----ESILET 443
A+L + + ++ + + L + D +E+RVK L++E +EK E +
Sbjct: 786 DAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVK-LLQEENEKLQGRSEELERR 844
Query: 444 KQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI----DELKSKLSTEKAIKDIXXXX 499
+Q+++E K D K +++Y+ + + E + E K +S +A+++
Sbjct: 845 VAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALEN-ELEG 903
Query: 500 XXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLR-EFG-AFDNL-NDVGNM 556
ES+ K E+L LKN++ R G + L ++ ++
Sbjct: 904 AQGNLSQTTQEQKQLSEKLKEESEQK---EQLRRLKNEMENERWHLGKTIEKLQKEMADI 960
Query: 557 INQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMT---EQEHVLNKKEKEIKMLNEKE 613
+ R EL + +EY EK + + E++R ++ T E+ + K ++ L E+E
Sbjct: 961 VEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDGMRLMEEE 1020
Score = 50.4 bits (115), Expect = 2e-05
Identities = 63/265 (23%), Positives = 115/265 (43%), Gaps = 25/265 (9%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD 435
K+ +++K E A L E+ ++N+ +EE TLQ+ +++ E ELR + L+
Sbjct: 635 KNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEE-----SEGELR-----KNLE 684
Query: 436 EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLL-FEKGEEIDELKSKLSTEKAIKD 494
E + ++ Q E+ + L E++ KR EKG I+EL L ++ ++D
Sbjct: 685 ELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEEL---LQAKQDLQD 741
Query: 495 IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQ----ITQLREF--GAFD 548
+ + ++ S+ +E+ LK Q + LRE A
Sbjct: 742 LLIAKEGREDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATK 801
Query: 549 NLNDVGNMIN--QQRDKLFEL-TKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKE 605
N+ + + N +Q E+ K +E +EKLQ + E++R V + Q L E +
Sbjct: 802 NVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAK 861
Query: 606 IKMLNEKEEEHMNIIN--LLHNKLE 628
K +K E + + L+H + E
Sbjct: 862 AKETLKKYEGEIRQLEEALVHARKE 886
Score = 48.0 bits (109), Expect = 1e-04
Identities = 98/540 (18%), Positives = 211/540 (39%), Gaps = 43/540 (7%)
Query: 144 EETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEIND 203
E+ L KR+ + + + +E + + ++++AE L+ S++ E K +
Sbjct: 750 EDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVE----EATKNVEV 805
Query: 204 IIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXX 263
+ + + ++R K L L ++ E+ +++ +
Sbjct: 806 LASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKET 865
Query: 264 XXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXX 323
+ ++ L A + K V LE LE A+ +L +T
Sbjct: 866 LKKYEGEIRQL-EEALVHARKEEKEAVSARRALENELEGAQG---NLSQTTQEQKQLSEK 921
Query: 324 XXEDFDQ--ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDM 381
E+ +Q +L +L +++ HL EKLQ + + +
Sbjct: 922 LKEESEQKEQLRRLKNEMENERWHLGKTI---EKLQKEMADIVEASRTSTLELQNQLDEY 978
Query: 382 KHEMNLNIAKLI-EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESI 440
K + +A++ ++++K ++ + + T + D +R L+E ELR D R DE
Sbjct: 979 KEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDGMR--LMEEELR--DYQRAQDEA--- 1031
Query: 441 LETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXX 500
L +Q +++ L+ + +LE + ++ RL+ + ++ +L+ +L E+ D+
Sbjct: 1032 LTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEAKVSQLEMELEEERNNSDLLSERI 1091
Query: 501 XXXXXXXXXXXXXXXXXXXRESQMK----SYYEELMNLKNQITQLREFGAFDNLNDVGNM 556
++ S + +LK++I L G++ + + +
Sbjct: 1092 SRSREQMEQLRNGLLQERAARQDLECGKISLERQNKDLKSRIIHLE--GSYRSSKE--GL 1147
Query: 557 INQQRDKLFELTKR--QEEYDE-KLQTKENEIKRLVE-----------SMTEQEHVLNKK 602
+ Q ++ EL R EE D LQ ++R V+ S+T+Q+ L+ +
Sbjct: 1148 VVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLR 1207
Query: 603 EKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVL 662
K +K E+ EE ++ + KL+ E +D+ L S+ L + ++VL
Sbjct: 1208 LKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPSKVL 1267
>BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 58.0 bits (134), Expect = 1e-07
Identities = 137/721 (19%), Positives = 278/721 (38%), Gaps = 68/721 (9%)
Query: 4 EELEIQQNQTDGCLYEDLNEQESITSESHKI-TKLKTVWQEKMVTFEKSKKELEDRQNQV 62
E+ Q + L E L + + +E+ ++ +L QE + + LE+ +++
Sbjct: 879 EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRG 938
Query: 63 MELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLD 122
+L A + ++M L +++ A + + K++ E ++ E + L +
Sbjct: 939 QQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ-LEKVTAEAKIKKL---EDEILVMDDQN 994
Query: 123 NKVTFDVNKLLNIPNSLVDKCEETLFKRKEII---NWFESLMSQEKGISTKTLTMKIKEF 179
NK++ + L + L E K K + N ES++S+ + K ++
Sbjct: 995 NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE-----LEVRLKKEEKS 1049
Query: 180 NAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEM 239
E + LK L+ ++F ++I D+ + A M L + +EL AL+ L+ + A+
Sbjct: 1050 RQELEKLKRKLEGDASDFHEQIADL---QAQIAELKMQLAKKEEELQAALARLDDEIAQK 1106
Query: 240 R---KQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQL 296
K+I + H + K L LKT +E +
Sbjct: 1107 NNALKKIRELEGHISDLQEDLDSERAARNKAEK-----QKRDLGEELEALKTELEDTLDS 1161
Query: 297 EAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELN-KLTQSIKDNTTHLEDIALAREK 355
A ++ R++ + E QE+ K Q++++ T LE A+
Sbjct: 1162 TATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKAN 1221
Query: 356 LQSXXXXXXXXXXXXSASYN---KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQEN 412
L + ++ ++++H+ A++ E++ K +D + L +
Sbjct: 1222 LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDK 1281
Query: 413 IDDLRTD-------LLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEI 465
+ L+ + L E+E + L +++ S L+ Q + +E K ++ + ++
Sbjct: 1282 VHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQL 1341
Query: 466 EEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMK 525
EE + L ++ +E E+++K + E+ I + E K
Sbjct: 1342 EEERNSLQDQLDE--EMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEAL----EEGKK 1395
Query: 526 SYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLF-----------ELTKRQEEY 574
+ +E+ NL Q + + A+D L N + Q+ D L L K+Q ++
Sbjct: 1396 RFQKEIENLTQQYEE--KAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKF 1453
Query: 575 DEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLN---------EKEEEHMNIINLLHN 625
D+ L ++N + + E +EKE K L+ E +EE +L
Sbjct: 1454 DQLLAEEKNISSKYADERDRAE--AEAREKETKALSLARALEEALEAKEELERTNKMLKA 1511
Query: 626 KLELRNEADIDV---IITLAKYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRTLRKNMSG 682
++E + DV + L K K++L +E+M L+ L L NM
Sbjct: 1512 EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA 1571
Query: 683 L 683
L
Sbjct: 1572 L 1572
Score = 50.8 bits (116), Expect = 2e-05
Identities = 47/226 (20%), Positives = 108/226 (47%), Gaps = 12/226 (5%)
Query: 276 KDRLSRAEHQLKTNVERVVQL--EAAL--EQARSESWSLERTVXXXXXXXXXXXEDFDQE 331
K+R +AE++LK ++ QL E L EQ ++E+ L ++ ++
Sbjct: 865 KERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEEMRVRLAAKKQELEEI 923
Query: 332 LNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNK-SIKDMKHEMNLNIA 390
L+++ +++ + + R+K+ A+ K ++ + E +
Sbjct: 924 LHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKL 983
Query: 391 K--LIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQ 448
+ ++ ++ + N +E+K L+E I DL T+L E E + K+L + ++ ES++ +
Sbjct: 984 EDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRL 1043
Query: 449 KELESTKTDLEHRKTEIE----EYKRLLFEKGEEIDELKSKLSTEK 490
K+ E ++ +LE K ++E ++ + + +I ELK +L+ ++
Sbjct: 1044 KKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1089
Score = 48.8 bits (111), Expect = 7e-05
Identities = 112/611 (18%), Positives = 235/611 (38%), Gaps = 37/611 (6%)
Query: 24 QESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQN---QVMELYASLRNTHRKMKLLG 80
QE + + TKL+ + +E+ ++ +E+E +QN + L L ++ +K++
Sbjct: 1325 QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFA 1384
Query: 81 QKVN-LPSAE---ELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIP 136
V L + + I N+ + E+ + K LD+ V D++ +
Sbjct: 1385 STVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV-DLDNQRQLV 1443
Query: 137 NSLVDK---CEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQL 193
++L K ++ L + K I + + + + + + T + A + L++ +
Sbjct: 1444 SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELE 1503
Query: 194 RT-EFLK-EINDII---DCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDH 248
RT + LK E+ D++ D + KN +E L+ + L + ++ TQ E+ ++ + +
Sbjct: 1504 RTNKMLKAEMEDLVSSKDDVGKNVHE---LEKSKRALETQMEEMKTQLEELEDELQATED 1560
Query: 249 H--RPYANRNXXXXXXXXXXXXXXXXSIMKDR-LSRAEHQLKTNVERVVQLEAALEQARS 305
R N + K R L R H+ +T +E + A A+
Sbjct: 1561 AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK 1620
Query: 306 ESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXX 365
+ + + E+ ++L KL +KD LED +R+++ +
Sbjct: 1621 KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK 1680
Query: 366 XXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESEL 425
A + +D+ K ++EK+ + EE + + L+ + E
Sbjct: 1681 KAKSLEADLMQLQEDLAAAERAR--KQADLEKE--ELAEELASSLSGRNALQDEKRRLEA 1736
Query: 426 RVKDLVRELDEKESILET------KQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI 479
R+ L EL+E++ +E K Q E S + E + E R E+ +
Sbjct: 1737 RIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNK- 1795
Query: 480 DELKSKL-STEKAIKD-IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQ 537
EL+SKL E A+K +++ KS ++ LK
Sbjct: 1796 -ELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEI 1854
Query: 538 ITQLR-EFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQE 596
+ Q+ E + + N + +L + EE +++ +++R ++ TE
Sbjct: 1855 LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESN 1914
Query: 597 HVLNKKEKEIK 607
+ ++ +K
Sbjct: 1915 EAMGREVNALK 1925
Score = 44.4 bits (100), Expect = 0.001
Identities = 115/646 (17%), Positives = 241/646 (37%), Gaps = 58/646 (8%)
Query: 20 DLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLL 79
D N+Q + +L+ + Q K E KK+LE QV EL + + R L
Sbjct: 1223 DKNKQTLEKENADLAGELRVLGQAKQEV-EHKKKKLEA---QVQELQSKCSDGERARAEL 1278
Query: 80 GQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSL 139
KV+ E + + + + ++L + + + + + LN+ L
Sbjct: 1279 NDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKL 1338
Query: 140 VDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLK-SSLDQLRTEFL 198
EE + ++ E+ + E+ IST + + + ++ +L++ + F
Sbjct: 1339 RQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ 1398
Query: 199 KEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXX 258
KEI ++ + A L+ L L DL R+ + + + + ++
Sbjct: 1399 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQ--- 1455
Query: 259 XXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERT---VX 315
S D RAE + + + + L ALE+A LERT +
Sbjct: 1456 -----LLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLK 1510
Query: 316 XXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKL----QSXXXXXXXXXXXXS 371
+D + +++L +S + T +E++ E+L Q+
Sbjct: 1511 AEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ 1570
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKK---YNDSIEE-----------KKTLQENIDDLR 417
A + +D++ N K +++++ Y +E+ KK L+ ++ DL
Sbjct: 1571 ALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLE 1630
Query: 418 TD--------------LLESELRVKDLVRELDE----KESILETKQCVQKELESTKTDLE 459
L + + ++KD REL++ ++ I T + +K+ +S + DL
Sbjct: 1631 LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLM 1690
Query: 460 HRKTEIEEYKRLL----FEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXX 515
+ ++ +R EK E +EL S LS A++D
Sbjct: 1691 QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQG 1750
Query: 516 XXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYD 575
+++ ++ L N++ R A N + + Q ++ +L + +
Sbjct: 1751 NMEAMSDRVRKATQQAEQLSNELATERS-TAQKNESARQQLERQNKELRSKLHEMEGAVK 1809
Query: 576 EKLQTKENEIKRLVESMTEQ-EHVLNKKEKEIKMLNEKEEEHMNII 620
K ++ ++ + + EQ E +K+ K L +K+++ I+
Sbjct: 1810 SKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEIL 1855
Score = 44.0 bits (99), Expect = 0.002
Identities = 103/508 (20%), Positives = 199/508 (39%), Gaps = 52/508 (10%)
Query: 2 KQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQ 61
K+EEL+ + D + + N + I I+ L+ + K++K+ D +
Sbjct: 1088 KEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEE 1147
Query: 62 VMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTL 121
+ L L +T + + L + E + + K E+ A + +H+
Sbjct: 1148 LEALKTELEDT---LDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA 1204
Query: 122 DNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNA 181
++T + + +L DK ++TL K + ++ Q K + + K K+ A
Sbjct: 1205 VEELTEQLEQFKRAKANL-DKNKQTLEKENADLAGELRVLGQAK----QEVEHKKKKLEA 1259
Query: 182 ENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRK 241
+ L+S E+ND + K NE ++ E L A +
Sbjct: 1260 QVQELQSKCSD-GERARAELNDKV---HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS 1315
Query: 242 QIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVER-VVQLEAAL 300
Q+ R S ++D+L E + K N+ER + L L
Sbjct: 1316 QLQDTQELLQEETRQKLNVSTKLRQLEEERNS-LQDQLDE-EMEAKQNLERHISTLNIQL 1373
Query: 301 EQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXX 360
++ + TV + F +E+ LTQ ++ + + + +LQ
Sbjct: 1374 SDSKKKLQDFASTV----EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQ-- 1427
Query: 361 XXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDL 420
+ + D+ ++ L ++ L + ++K++ + E+K + D R D
Sbjct: 1428 ------------ELDDLVVDLDNQRQL-VSNLEKKQRKFDQLLAEEKNISSKYADER-DR 1473
Query: 421 LESELRVKD-----LVRELDE----KESILETKQCVQKELE---STKTDLEHRKTEIEEY 468
E+E R K+ L R L+E KE + T + ++ E+E S+K D+ E+E+
Sbjct: 1474 AEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKS 1533
Query: 469 KRLLFEKGEE----IDELKSKL-STEKA 491
KR L + EE ++EL+ +L +TE A
Sbjct: 1534 KRALETQMEEMKTQLEELEDELQATEDA 1561
Score = 39.1 bits (87), Expect = 0.053
Identities = 48/225 (21%), Positives = 101/225 (44%), Gaps = 14/225 (6%)
Query: 405 EKKTLQENIDDLRTDLLESELRVKDLVRELDEKESIL-ETKQCVQKELESTKTDLEHRKT 463
+++ +Q D+L+ E + + ++ ++EL++K S L E K +Q++L++ +T+L
Sbjct: 850 QEEEMQAKEDELQKTK-ERQQKAENELKELEQKHSQLTEEKNLLQEQLQA-ETELY---A 904
Query: 464 EIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQ 523
E EE + L K +E++E+ ++ ++ E Q
Sbjct: 905 EAEEMRVRLAAKKQELEEILHEMEARLEEEE------DRGQQLQAERKKMAQQMLDLEEQ 958
Query: 524 MKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKEN 583
++ EE K Q+ ++ L D +++ Q +KL + K EE L T
Sbjct: 959 LEE--EEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLA 1016
Query: 584 EIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
E + +++T+ ++ E+++ +KEE+ + L KLE
Sbjct: 1017 EEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLE 1061
Score = 32.7 bits (71), Expect = 4.6
Identities = 29/96 (30%), Positives = 50/96 (52%), Gaps = 16/96 (16%)
Query: 564 LFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLL 623
L ++T+++EE +Q KE+E+++ E K E E+K L +K + NLL
Sbjct: 844 LLQVTRQEEE----MQAKEDELQKTKERQ-------QKAENELKELEQKHSQLTEEKNLL 892
Query: 624 HNKL----ELRNEADIDVIITLAKYKKSLTLVLEKM 655
+L EL EA+ ++ + LA K+ L +L +M
Sbjct: 893 QEQLQAETELYAEAE-EMRVRLAAKKQELEEILHEM 927
>BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 58.0 bits (134), Expect = 1e-07
Identities = 137/721 (19%), Positives = 278/721 (38%), Gaps = 68/721 (9%)
Query: 4 EELEIQQNQTDGCLYEDLNEQESITSESHKI-TKLKTVWQEKMVTFEKSKKELEDRQNQV 62
E+ Q + L E L + + +E+ ++ +L QE + + LE+ +++
Sbjct: 879 EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRG 938
Query: 63 MELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLD 122
+L A + ++M L +++ A + + K++ E ++ E + L +
Sbjct: 939 QQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ-LEKVTAEAKIKKL---EDEILVMDDQN 994
Query: 123 NKVTFDVNKLLNIPNSLVDKCEETLFKRKEII---NWFESLMSQEKGISTKTLTMKIKEF 179
NK++ + L + L E K K + N ES++S+ + K ++
Sbjct: 995 NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE-----LEVRLKKEEKS 1049
Query: 180 NAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEM 239
E + LK L+ ++F ++I D+ + A M L + +EL AL+ L+ + A+
Sbjct: 1050 RQELEKLKRKLEGDASDFHEQIADL---QAQIAELKMQLAKKEEELQAALARLDDEIAQK 1106
Query: 240 R---KQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQL 296
K+I + H + K L LKT +E +
Sbjct: 1107 NNALKKIRELEGHISDLQEDLDSERAARNKAEK-----QKRDLGEELEALKTELEDTLDS 1161
Query: 297 EAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELN-KLTQSIKDNTTHLEDIALAREK 355
A ++ R++ + E QE+ K Q++++ T LE A+
Sbjct: 1162 TATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKAN 1221
Query: 356 LQSXXXXXXXXXXXXSASYN---KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQEN 412
L + ++ ++++H+ A++ E++ K +D + L +
Sbjct: 1222 LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDK 1281
Query: 413 IDDLRTD-------LLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEI 465
+ L+ + L E+E + L +++ S L+ Q + +E K ++ + ++
Sbjct: 1282 VHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQL 1341
Query: 466 EEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMK 525
EE + L ++ +E E+++K + E+ I + E K
Sbjct: 1342 EEERNSLQDQLDE--EMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEAL----EEGKK 1395
Query: 526 SYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLF-----------ELTKRQEEY 574
+ +E+ NL Q + + A+D L N + Q+ D L L K+Q ++
Sbjct: 1396 RFQKEIENLTQQYEE--KAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKF 1453
Query: 575 DEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLN---------EKEEEHMNIINLLHN 625
D+ L ++N + + E +EKE K L+ E +EE +L
Sbjct: 1454 DQLLAEEKNISSKYADERDRAE--AEAREKETKALSLARALEEALEAKEELERTNKMLKA 1511
Query: 626 KLELRNEADIDV---IITLAKYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRTLRKNMSG 682
++E + DV + L K K++L +E+M L+ L L NM
Sbjct: 1512 EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA 1571
Query: 683 L 683
L
Sbjct: 1572 L 1572
Score = 50.8 bits (116), Expect = 2e-05
Identities = 47/226 (20%), Positives = 108/226 (47%), Gaps = 12/226 (5%)
Query: 276 KDRLSRAEHQLKTNVERVVQL--EAAL--EQARSESWSLERTVXXXXXXXXXXXEDFDQE 331
K+R +AE++LK ++ QL E L EQ ++E+ L ++ ++
Sbjct: 865 KERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEEMRVRLAAKKQELEEI 923
Query: 332 LNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNK-SIKDMKHEMNLNIA 390
L+++ +++ + + R+K+ A+ K ++ + E +
Sbjct: 924 LHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKL 983
Query: 391 K--LIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQ 448
+ ++ ++ + N +E+K L+E I DL T+L E E + K+L + ++ ES++ +
Sbjct: 984 EDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRL 1043
Query: 449 KELESTKTDLEHRKTEIE----EYKRLLFEKGEEIDELKSKLSTEK 490
K+ E ++ +LE K ++E ++ + + +I ELK +L+ ++
Sbjct: 1044 KKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1089
Score = 48.8 bits (111), Expect = 7e-05
Identities = 112/611 (18%), Positives = 235/611 (38%), Gaps = 37/611 (6%)
Query: 24 QESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQN---QVMELYASLRNTHRKMKLLG 80
QE + + TKL+ + +E+ ++ +E+E +QN + L L ++ +K++
Sbjct: 1325 QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFA 1384
Query: 81 QKVN-LPSAE---ELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIP 136
V L + + I N+ + E+ + K LD+ V D++ +
Sbjct: 1385 STVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV-DLDNQRQLV 1443
Query: 137 NSLVDK---CEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQL 193
++L K ++ L + K I + + + + + + T + A + L++ +
Sbjct: 1444 SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELE 1503
Query: 194 RT-EFLK-EINDII---DCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDH 248
RT + LK E+ D++ D + KN +E L+ + L + ++ TQ E+ ++ + +
Sbjct: 1504 RTNKMLKAEMEDLVSSKDDVGKNVHE---LEKSKRALETQMEEMKTQLEELEDELQATED 1560
Query: 249 H--RPYANRNXXXXXXXXXXXXXXXXSIMKDR-LSRAEHQLKTNVERVVQLEAALEQARS 305
R N + K R L R H+ +T +E + A A+
Sbjct: 1561 AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK 1620
Query: 306 ESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXX 365
+ + + E+ ++L KL +KD LED +R+++ +
Sbjct: 1621 KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK 1680
Query: 366 XXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESEL 425
A + +D+ K ++EK+ + EE + + L+ + E
Sbjct: 1681 KAKSLEADLMQLQEDLAAAERAR--KQADLEKE--ELAEELASSLSGRNALQDEKRRLEA 1736
Query: 426 RVKDLVRELDEKESILET------KQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI 479
R+ L EL+E++ +E K Q E S + E + E R E+ +
Sbjct: 1737 RIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNK- 1795
Query: 480 DELKSKL-STEKAIKD-IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQ 537
EL+SKL E A+K +++ KS ++ LK
Sbjct: 1796 -ELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEI 1854
Query: 538 ITQLR-EFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQE 596
+ Q+ E + + N + +L + EE +++ +++R ++ TE
Sbjct: 1855 LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESN 1914
Query: 597 HVLNKKEKEIK 607
+ ++ +K
Sbjct: 1915 EAMGREVNALK 1925
Score = 44.4 bits (100), Expect = 0.001
Identities = 115/646 (17%), Positives = 241/646 (37%), Gaps = 58/646 (8%)
Query: 20 DLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLL 79
D N+Q + +L+ + Q K E KK+LE QV EL + + R L
Sbjct: 1223 DKNKQTLEKENADLAGELRVLGQAKQEV-EHKKKKLEA---QVQELQSKCSDGERARAEL 1278
Query: 80 GQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSL 139
KV+ E + + + + ++L + + + + + LN+ L
Sbjct: 1279 NDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKL 1338
Query: 140 VDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLK-SSLDQLRTEFL 198
EE + ++ E+ + E+ IST + + + ++ +L++ + F
Sbjct: 1339 RQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ 1398
Query: 199 KEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXX 258
KEI ++ + A L+ L L DL R+ + + + + ++
Sbjct: 1399 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQ--- 1455
Query: 259 XXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERT---VX 315
S D RAE + + + + L ALE+A LERT +
Sbjct: 1456 -----LLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLK 1510
Query: 316 XXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKL----QSXXXXXXXXXXXXS 371
+D + +++L +S + T +E++ E+L Q+
Sbjct: 1511 AEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ 1570
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKK---YNDSIEE-----------KKTLQENIDDLR 417
A + +D++ N K +++++ Y +E+ KK L+ ++ DL
Sbjct: 1571 ALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLE 1630
Query: 418 TD--------------LLESELRVKDLVRELDE----KESILETKQCVQKELESTKTDLE 459
L + + ++KD REL++ ++ I T + +K+ +S + DL
Sbjct: 1631 LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLM 1690
Query: 460 HRKTEIEEYKRLL----FEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXX 515
+ ++ +R EK E +EL S LS A++D
Sbjct: 1691 QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQG 1750
Query: 516 XXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYD 575
+++ ++ L N++ R A N + + Q ++ +L + +
Sbjct: 1751 NMEAMSDRVRKATQQAEQLSNELATERS-TAQKNESARQQLERQNKELRSKLHEMEGAVK 1809
Query: 576 EKLQTKENEIKRLVESMTEQ-EHVLNKKEKEIKMLNEKEEEHMNII 620
K ++ ++ + + EQ E +K+ K L +K+++ I+
Sbjct: 1810 SKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEIL 1855
Score = 44.0 bits (99), Expect = 0.002
Identities = 103/508 (20%), Positives = 199/508 (39%), Gaps = 52/508 (10%)
Query: 2 KQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQ 61
K+EEL+ + D + + N + I I+ L+ + K++K+ D +
Sbjct: 1088 KEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEE 1147
Query: 62 VMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTL 121
+ L L +T + + L + E + + K E+ A + +H+
Sbjct: 1148 LEALKTELEDT---LDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA 1204
Query: 122 DNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNA 181
++T + + +L DK ++TL K + ++ Q K + + K K+ A
Sbjct: 1205 VEELTEQLEQFKRAKANL-DKNKQTLEKENADLAGELRVLGQAK----QEVEHKKKKLEA 1259
Query: 182 ENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRK 241
+ L+S E+ND + K NE ++ E L A +
Sbjct: 1260 QVQELQSKCSD-GERARAELNDKV---HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS 1315
Query: 242 QIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVER-VVQLEAAL 300
Q+ R S ++D+L E + K N+ER + L L
Sbjct: 1316 QLQDTQELLQEETRQKLNVSTKLRQLEEERNS-LQDQLDE-EMEAKQNLERHISTLNIQL 1373
Query: 301 EQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXX 360
++ + TV + F +E+ LTQ ++ + + + +LQ
Sbjct: 1374 SDSKKKLQDFASTV----EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQ-- 1427
Query: 361 XXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDL 420
+ + D+ ++ L ++ L + ++K++ + E+K + D R D
Sbjct: 1428 ------------ELDDLVVDLDNQRQL-VSNLEKKQRKFDQLLAEEKNISSKYADER-DR 1473
Query: 421 LESELRVKD-----LVRELDE----KESILETKQCVQKELE---STKTDLEHRKTEIEEY 468
E+E R K+ L R L+E KE + T + ++ E+E S+K D+ E+E+
Sbjct: 1474 AEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKS 1533
Query: 469 KRLLFEKGEE----IDELKSKL-STEKA 491
KR L + EE ++EL+ +L +TE A
Sbjct: 1534 KRALETQMEEMKTQLEELEDELQATEDA 1561
Score = 39.1 bits (87), Expect = 0.053
Identities = 48/225 (21%), Positives = 101/225 (44%), Gaps = 14/225 (6%)
Query: 405 EKKTLQENIDDLRTDLLESELRVKDLVRELDEKESIL-ETKQCVQKELESTKTDLEHRKT 463
+++ +Q D+L+ E + + ++ ++EL++K S L E K +Q++L++ +T+L
Sbjct: 850 QEEEMQAKEDELQKTK-ERQQKAENELKELEQKHSQLTEEKNLLQEQLQA-ETELY---A 904
Query: 464 EIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQ 523
E EE + L K +E++E+ ++ ++ E Q
Sbjct: 905 EAEEMRVRLAAKKQELEEILHEMEARLEEEE------DRGQQLQAERKKMAQQMLDLEEQ 958
Query: 524 MKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKEN 583
++ EE K Q+ ++ L D +++ Q +KL + K EE L T
Sbjct: 959 LEE--EEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLA 1016
Query: 584 EIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
E + +++T+ ++ E+++ +KEE+ + L KLE
Sbjct: 1017 EEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLE 1061
Score = 32.7 bits (71), Expect = 4.6
Identities = 29/96 (30%), Positives = 50/96 (52%), Gaps = 16/96 (16%)
Query: 564 LFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLL 623
L ++T+++EE +Q KE+E+++ E K E E+K L +K + NLL
Sbjct: 844 LLQVTRQEEE----MQAKEDELQKTKERQ-------QKAENELKELEQKHSQLTEEKNLL 892
Query: 624 HNKL----ELRNEADIDVIITLAKYKKSLTLVLEKM 655
+L EL EA+ ++ + LA K+ L +L +M
Sbjct: 893 QEQLQAETELYAEAE-EMRVRLAAKKQELEEILHEM 927
>AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin heavy
chain isoform SM2 protein.
Length = 1945
Score = 58.0 bits (134), Expect = 1e-07
Identities = 137/721 (19%), Positives = 278/721 (38%), Gaps = 68/721 (9%)
Query: 4 EELEIQQNQTDGCLYEDLNEQESITSESHKI-TKLKTVWQEKMVTFEKSKKELEDRQNQV 62
E+ Q + L E L + + +E+ ++ +L QE + + LE+ +++
Sbjct: 886 EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRG 945
Query: 63 MELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLD 122
+L A + ++M L +++ A + + K++ E ++ E + L +
Sbjct: 946 QQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ-LEKVTAEAKIKKL---EDEILVMDDQN 1001
Query: 123 NKVTFDVNKLLNIPNSLVDKCEETLFKRKEII---NWFESLMSQEKGISTKTLTMKIKEF 179
NK++ + L + L E K K + N ES++S+ + K ++
Sbjct: 1002 NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE-----LEVRLKKEEKS 1056
Query: 180 NAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEM 239
E + LK L+ ++F ++I D+ + A M L + +EL AL+ L+ + A+
Sbjct: 1057 RQELEKLKRKLEGDASDFHEQIADL---QAQIAELKMQLAKKEEELQAALARLDDEIAQK 1113
Query: 240 R---KQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQL 296
K+I + H + K L LKT +E +
Sbjct: 1114 NNALKKIRELEGHISDLQEDLDSERAARNKAEK-----QKRDLGEELEALKTELEDTLDS 1168
Query: 297 EAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELN-KLTQSIKDNTTHLEDIALAREK 355
A ++ R++ + E QE+ K Q++++ T LE A+
Sbjct: 1169 TATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKAN 1228
Query: 356 LQSXXXXXXXXXXXXSASYN---KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQEN 412
L + ++ ++++H+ A++ E++ K +D + L +
Sbjct: 1229 LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDK 1288
Query: 413 IDDLRTD-------LLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEI 465
+ L+ + L E+E + L +++ S L+ Q + +E K ++ + ++
Sbjct: 1289 VHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQL 1348
Query: 466 EEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMK 525
EE + L ++ +E E+++K + E+ I + E K
Sbjct: 1349 EEERNSLQDQLDE--EMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEAL----EEGKK 1402
Query: 526 SYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLF-----------ELTKRQEEY 574
+ +E+ NL Q + + A+D L N + Q+ D L L K+Q ++
Sbjct: 1403 RFQKEIENLTQQYEE--KAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKF 1460
Query: 575 DEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLN---------EKEEEHMNIINLLHN 625
D+ L ++N + + E +EKE K L+ E +EE +L
Sbjct: 1461 DQLLAEEKNISSKYADERDRAE--AEAREKETKALSLARALEEALEAKEELERTNKMLKA 1518
Query: 626 KLELRNEADIDV---IITLAKYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRTLRKNMSG 682
++E + DV + L K K++L +E+M L+ L L NM
Sbjct: 1519 EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA 1578
Query: 683 L 683
L
Sbjct: 1579 L 1579
Score = 50.8 bits (116), Expect = 2e-05
Identities = 47/226 (20%), Positives = 108/226 (47%), Gaps = 12/226 (5%)
Query: 276 KDRLSRAEHQLKTNVERVVQL--EAAL--EQARSESWSLERTVXXXXXXXXXXXEDFDQE 331
K+R +AE++LK ++ QL E L EQ ++E+ L ++ ++
Sbjct: 872 KERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEEMRVRLAAKKQELEEI 930
Query: 332 LNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNK-SIKDMKHEMNLNIA 390
L+++ +++ + + R+K+ A+ K ++ + E +
Sbjct: 931 LHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKL 990
Query: 391 K--LIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQ 448
+ ++ ++ + N +E+K L+E I DL T+L E E + K+L + ++ ES++ +
Sbjct: 991 EDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRL 1050
Query: 449 KELESTKTDLEHRKTEIE----EYKRLLFEKGEEIDELKSKLSTEK 490
K+ E ++ +LE K ++E ++ + + +I ELK +L+ ++
Sbjct: 1051 KKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1096
Score = 48.8 bits (111), Expect = 7e-05
Identities = 112/611 (18%), Positives = 235/611 (38%), Gaps = 37/611 (6%)
Query: 24 QESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQN---QVMELYASLRNTHRKMKLLG 80
QE + + TKL+ + +E+ ++ +E+E +QN + L L ++ +K++
Sbjct: 1332 QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFA 1391
Query: 81 QKVN-LPSAE---ELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIP 136
V L + + I N+ + E+ + K LD+ V D++ +
Sbjct: 1392 STVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV-DLDNQRQLV 1450
Query: 137 NSLVDK---CEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQL 193
++L K ++ L + K I + + + + + + T + A + L++ +
Sbjct: 1451 SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELE 1510
Query: 194 RT-EFLK-EINDII---DCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDH 248
RT + LK E+ D++ D + KN +E L+ + L + ++ TQ E+ ++ + +
Sbjct: 1511 RTNKMLKAEMEDLVSSKDDVGKNVHE---LEKSKRALETQMEEMKTQLEELEDELQATED 1567
Query: 249 H--RPYANRNXXXXXXXXXXXXXXXXSIMKDR-LSRAEHQLKTNVERVVQLEAALEQARS 305
R N + K R L R H+ +T +E + A A+
Sbjct: 1568 AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK 1627
Query: 306 ESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXX 365
+ + + E+ ++L KL +KD LED +R+++ +
Sbjct: 1628 KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK 1687
Query: 366 XXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESEL 425
A + +D+ K ++EK+ + EE + + L+ + E
Sbjct: 1688 KAKSLEADLMQLQEDLAAAERAR--KQADLEKE--ELAEELASSLSGRNALQDEKRRLEA 1743
Query: 426 RVKDLVRELDEKESILET------KQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI 479
R+ L EL+E++ +E K Q E S + E + E R E+ +
Sbjct: 1744 RIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNK- 1802
Query: 480 DELKSKL-STEKAIKD-IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQ 537
EL+SKL E A+K +++ KS ++ LK
Sbjct: 1803 -ELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEI 1861
Query: 538 ITQLR-EFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQE 596
+ Q+ E + + N + +L + EE +++ +++R ++ TE
Sbjct: 1862 LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESN 1921
Query: 597 HVLNKKEKEIK 607
+ ++ +K
Sbjct: 1922 EAMGREVNALK 1932
Score = 44.4 bits (100), Expect = 0.001
Identities = 115/646 (17%), Positives = 241/646 (37%), Gaps = 58/646 (8%)
Query: 20 DLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLL 79
D N+Q + +L+ + Q K E KK+LE QV EL + + R L
Sbjct: 1230 DKNKQTLEKENADLAGELRVLGQAKQEV-EHKKKKLEA---QVQELQSKCSDGERARAEL 1285
Query: 80 GQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSL 139
KV+ E + + + + ++L + + + + + LN+ L
Sbjct: 1286 NDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKL 1345
Query: 140 VDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLK-SSLDQLRTEFL 198
EE + ++ E+ + E+ IST + + + ++ +L++ + F
Sbjct: 1346 RQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ 1405
Query: 199 KEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXX 258
KEI ++ + A L+ L L DL R+ + + + + ++
Sbjct: 1406 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQ--- 1462
Query: 259 XXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERT---VX 315
S D RAE + + + + L ALE+A LERT +
Sbjct: 1463 -----LLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLK 1517
Query: 316 XXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKL----QSXXXXXXXXXXXXS 371
+D + +++L +S + T +E++ E+L Q+
Sbjct: 1518 AEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ 1577
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKK---YNDSIEE-----------KKTLQENIDDLR 417
A + +D++ N K +++++ Y +E+ KK L+ ++ DL
Sbjct: 1578 ALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLE 1637
Query: 418 TD--------------LLESELRVKDLVRELDE----KESILETKQCVQKELESTKTDLE 459
L + + ++KD REL++ ++ I T + +K+ +S + DL
Sbjct: 1638 LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLM 1697
Query: 460 HRKTEIEEYKRLL----FEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXX 515
+ ++ +R EK E +EL S LS A++D
Sbjct: 1698 QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQG 1757
Query: 516 XXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYD 575
+++ ++ L N++ R A N + + Q ++ +L + +
Sbjct: 1758 NMEAMSDRVRKATQQAEQLSNELATERS-TAQKNESARQQLERQNKELRSKLHEMEGAVK 1816
Query: 576 EKLQTKENEIKRLVESMTEQ-EHVLNKKEKEIKMLNEKEEEHMNII 620
K ++ ++ + + EQ E +K+ K L +K+++ I+
Sbjct: 1817 SKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEIL 1862
Score = 44.0 bits (99), Expect = 0.002
Identities = 103/508 (20%), Positives = 199/508 (39%), Gaps = 52/508 (10%)
Query: 2 KQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQ 61
K+EEL+ + D + + N + I I+ L+ + K++K+ D +
Sbjct: 1095 KEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEE 1154
Query: 62 VMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTL 121
+ L L +T + + L + E + + K E+ A + +H+
Sbjct: 1155 LEALKTELEDT---LDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA 1211
Query: 122 DNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNA 181
++T + + +L DK ++TL K + ++ Q K + + K K+ A
Sbjct: 1212 VEELTEQLEQFKRAKANL-DKNKQTLEKENADLAGELRVLGQAK----QEVEHKKKKLEA 1266
Query: 182 ENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRK 241
+ L+S E+ND + K NE ++ E L A +
Sbjct: 1267 QVQELQSKCSD-GERARAELNDKV---HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS 1322
Query: 242 QIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVER-VVQLEAAL 300
Q+ R S ++D+L E + K N+ER + L L
Sbjct: 1323 QLQDTQELLQEETRQKLNVSTKLRQLEEERNS-LQDQLDE-EMEAKQNLERHISTLNIQL 1380
Query: 301 EQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXX 360
++ + TV + F +E+ LTQ ++ + + + +LQ
Sbjct: 1381 SDSKKKLQDFASTV----EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQ-- 1434
Query: 361 XXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDL 420
+ + D+ ++ L ++ L + ++K++ + E+K + D R D
Sbjct: 1435 ------------ELDDLVVDLDNQRQL-VSNLEKKQRKFDQLLAEEKNISSKYADER-DR 1480
Query: 421 LESELRVKD-----LVRELDE----KESILETKQCVQKELE---STKTDLEHRKTEIEEY 468
E+E R K+ L R L+E KE + T + ++ E+E S+K D+ E+E+
Sbjct: 1481 AEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKS 1540
Query: 469 KRLLFEKGEE----IDELKSKL-STEKA 491
KR L + EE ++EL+ +L +TE A
Sbjct: 1541 KRALETQMEEMKTQLEELEDELQATEDA 1568
Score = 39.1 bits (87), Expect = 0.053
Identities = 48/225 (21%), Positives = 101/225 (44%), Gaps = 14/225 (6%)
Query: 405 EKKTLQENIDDLRTDLLESELRVKDLVRELDEKESIL-ETKQCVQKELESTKTDLEHRKT 463
+++ +Q D+L+ E + + ++ ++EL++K S L E K +Q++L++ +T+L
Sbjct: 857 QEEEMQAKEDELQKTK-ERQQKAENELKELEQKHSQLTEEKNLLQEQLQA-ETELY---A 911
Query: 464 EIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQ 523
E EE + L K +E++E+ ++ ++ E Q
Sbjct: 912 EAEEMRVRLAAKKQELEEILHEMEARLEEEE------DRGQQLQAERKKMAQQMLDLEEQ 965
Query: 524 MKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKEN 583
++ EE K Q+ ++ L D +++ Q +KL + K EE L T
Sbjct: 966 LEE--EEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLA 1023
Query: 584 EIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
E + +++T+ ++ E+++ +KEE+ + L KLE
Sbjct: 1024 EEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLE 1068
Score = 32.7 bits (71), Expect = 4.6
Identities = 29/96 (30%), Positives = 50/96 (52%), Gaps = 16/96 (16%)
Query: 564 LFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLL 623
L ++T+++EE +Q KE+E+++ E K E E+K L +K + NLL
Sbjct: 851 LLQVTRQEEE----MQAKEDELQKTKERQ-------QKAENELKELEQKHSQLTEEKNLL 899
Query: 624 HNKL----ELRNEADIDVIITLAKYKKSLTLVLEKM 655
+L EL EA+ ++ + LA K+ L +L +M
Sbjct: 900 QEQLQAETELYAEAE-EMRVRLAAKKQELEEILHEM 934
>AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin heavy
chain isoform SM1 protein.
Length = 1979
Score = 58.0 bits (134), Expect = 1e-07
Identities = 137/721 (19%), Positives = 278/721 (38%), Gaps = 68/721 (9%)
Query: 4 EELEIQQNQTDGCLYEDLNEQESITSESHKI-TKLKTVWQEKMVTFEKSKKELEDRQNQV 62
E+ Q + L E L + + +E+ ++ +L QE + + LE+ +++
Sbjct: 886 EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRG 945
Query: 63 MELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLD 122
+L A + ++M L +++ A + + K++ E ++ E + L +
Sbjct: 946 QQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ-LEKVTAEAKIKKL---EDEILVMDDQN 1001
Query: 123 NKVTFDVNKLLNIPNSLVDKCEETLFKRKEII---NWFESLMSQEKGISTKTLTMKIKEF 179
NK++ + L + L E K K + N ES++S+ + K ++
Sbjct: 1002 NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE-----LEVRLKKEEKS 1056
Query: 180 NAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEM 239
E + LK L+ ++F ++I D+ + A M L + +EL AL+ L+ + A+
Sbjct: 1057 RQELEKLKRKLEGDASDFHEQIADL---QAQIAELKMQLAKKEEELQAALARLDDEIAQK 1113
Query: 240 R---KQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQL 296
K+I + H + K L LKT +E +
Sbjct: 1114 NNALKKIRELEGHISDLQEDLDSERAARNKAEK-----QKRDLGEELEALKTELEDTLDS 1168
Query: 297 EAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELN-KLTQSIKDNTTHLEDIALAREK 355
A ++ R++ + E QE+ K Q++++ T LE A+
Sbjct: 1169 TATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKAN 1228
Query: 356 LQSXXXXXXXXXXXXSASYN---KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQEN 412
L + ++ ++++H+ A++ E++ K +D + L +
Sbjct: 1229 LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDK 1288
Query: 413 IDDLRTD-------LLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEI 465
+ L+ + L E+E + L +++ S L+ Q + +E K ++ + ++
Sbjct: 1289 VHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQL 1348
Query: 466 EEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMK 525
EE + L ++ +E E+++K + E+ I + E K
Sbjct: 1349 EEERNSLQDQLDE--EMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEAL----EEGKK 1402
Query: 526 SYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLF-----------ELTKRQEEY 574
+ +E+ NL Q + + A+D L N + Q+ D L L K+Q ++
Sbjct: 1403 RFQKEIENLTQQYEE--KAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKF 1460
Query: 575 DEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLN---------EKEEEHMNIINLLHN 625
D+ L ++N + + E +EKE K L+ E +EE +L
Sbjct: 1461 DQLLAEEKNISSKYADERDRAE--AEAREKETKALSLARALEEALEAKEELERTNKMLKA 1518
Query: 626 KLELRNEADIDV---IITLAKYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRTLRKNMSG 682
++E + DV + L K K++L +E+M L+ L L NM
Sbjct: 1519 EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA 1578
Query: 683 L 683
L
Sbjct: 1579 L 1579
Score = 50.8 bits (116), Expect = 2e-05
Identities = 47/226 (20%), Positives = 108/226 (47%), Gaps = 12/226 (5%)
Query: 276 KDRLSRAEHQLKTNVERVVQL--EAAL--EQARSESWSLERTVXXXXXXXXXXXEDFDQE 331
K+R +AE++LK ++ QL E L EQ ++E+ L ++ ++
Sbjct: 872 KERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEEMRVRLAAKKQELEEI 930
Query: 332 LNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNK-SIKDMKHEMNLNIA 390
L+++ +++ + + R+K+ A+ K ++ + E +
Sbjct: 931 LHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKL 990
Query: 391 K--LIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQ 448
+ ++ ++ + N +E+K L+E I DL T+L E E + K+L + ++ ES++ +
Sbjct: 991 EDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRL 1050
Query: 449 KELESTKTDLEHRKTEIE----EYKRLLFEKGEEIDELKSKLSTEK 490
K+ E ++ +LE K ++E ++ + + +I ELK +L+ ++
Sbjct: 1051 KKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1096
Score = 48.8 bits (111), Expect = 7e-05
Identities = 112/611 (18%), Positives = 235/611 (38%), Gaps = 37/611 (6%)
Query: 24 QESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQN---QVMELYASLRNTHRKMKLLG 80
QE + + TKL+ + +E+ ++ +E+E +QN + L L ++ +K++
Sbjct: 1332 QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFA 1391
Query: 81 QKVN-LPSAE---ELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIP 136
V L + + I N+ + E+ + K LD+ V D++ +
Sbjct: 1392 STVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV-DLDNQRQLV 1450
Query: 137 NSLVDK---CEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQL 193
++L K ++ L + K I + + + + + + T + A + L++ +
Sbjct: 1451 SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELE 1510
Query: 194 RT-EFLK-EINDII---DCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDH 248
RT + LK E+ D++ D + KN +E L+ + L + ++ TQ E+ ++ + +
Sbjct: 1511 RTNKMLKAEMEDLVSSKDDVGKNVHE---LEKSKRALETQMEEMKTQLEELEDELQATED 1567
Query: 249 H--RPYANRNXXXXXXXXXXXXXXXXSIMKDR-LSRAEHQLKTNVERVVQLEAALEQARS 305
R N + K R L R H+ +T +E + A A+
Sbjct: 1568 AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK 1627
Query: 306 ESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXX 365
+ + + E+ ++L KL +KD LED +R+++ +
Sbjct: 1628 KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK 1687
Query: 366 XXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESEL 425
A + +D+ K ++EK+ + EE + + L+ + E
Sbjct: 1688 KAKSLEADLMQLQEDLAAAERAR--KQADLEKE--ELAEELASSLSGRNALQDEKRRLEA 1743
Query: 426 RVKDLVRELDEKESILET------KQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI 479
R+ L EL+E++ +E K Q E S + E + E R E+ +
Sbjct: 1744 RIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNK- 1802
Query: 480 DELKSKL-STEKAIKD-IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQ 537
EL+SKL E A+K +++ KS ++ LK
Sbjct: 1803 -ELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEI 1861
Query: 538 ITQLR-EFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQE 596
+ Q+ E + + N + +L + EE +++ +++R ++ TE
Sbjct: 1862 LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESN 1921
Query: 597 HVLNKKEKEIK 607
+ ++ +K
Sbjct: 1922 EAMGREVNALK 1932
Score = 44.4 bits (100), Expect = 0.001
Identities = 115/646 (17%), Positives = 241/646 (37%), Gaps = 58/646 (8%)
Query: 20 DLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLL 79
D N+Q + +L+ + Q K E KK+LE QV EL + + R L
Sbjct: 1230 DKNKQTLEKENADLAGELRVLGQAKQEV-EHKKKKLEA---QVQELQSKCSDGERARAEL 1285
Query: 80 GQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSL 139
KV+ E + + + + ++L + + + + + LN+ L
Sbjct: 1286 NDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKL 1345
Query: 140 VDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLK-SSLDQLRTEFL 198
EE + ++ E+ + E+ IST + + + ++ +L++ + F
Sbjct: 1346 RQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ 1405
Query: 199 KEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXX 258
KEI ++ + A L+ L L DL R+ + + + + ++
Sbjct: 1406 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQ--- 1462
Query: 259 XXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERT---VX 315
S D RAE + + + + L ALE+A LERT +
Sbjct: 1463 -----LLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLK 1517
Query: 316 XXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKL----QSXXXXXXXXXXXXS 371
+D + +++L +S + T +E++ E+L Q+
Sbjct: 1518 AEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ 1577
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKK---YNDSIEE-----------KKTLQENIDDLR 417
A + +D++ N K +++++ Y +E+ KK L+ ++ DL
Sbjct: 1578 ALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLE 1637
Query: 418 TD--------------LLESELRVKDLVRELDE----KESILETKQCVQKELESTKTDLE 459
L + + ++KD REL++ ++ I T + +K+ +S + DL
Sbjct: 1638 LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLM 1697
Query: 460 HRKTEIEEYKRLL----FEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXX 515
+ ++ +R EK E +EL S LS A++D
Sbjct: 1698 QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQG 1757
Query: 516 XXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYD 575
+++ ++ L N++ R A N + + Q ++ +L + +
Sbjct: 1758 NMEAMSDRVRKATQQAEQLSNELATERS-TAQKNESARQQLERQNKELRSKLHEMEGAVK 1816
Query: 576 EKLQTKENEIKRLVESMTEQ-EHVLNKKEKEIKMLNEKEEEHMNII 620
K ++ ++ + + EQ E +K+ K L +K+++ I+
Sbjct: 1817 SKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEIL 1862
Score = 44.0 bits (99), Expect = 0.002
Identities = 103/508 (20%), Positives = 199/508 (39%), Gaps = 52/508 (10%)
Query: 2 KQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQ 61
K+EEL+ + D + + N + I I+ L+ + K++K+ D +
Sbjct: 1095 KEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEE 1154
Query: 62 VMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTL 121
+ L L +T + + L + E + + K E+ A + +H+
Sbjct: 1155 LEALKTELEDT---LDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA 1211
Query: 122 DNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNA 181
++T + + +L DK ++TL K + ++ Q K + + K K+ A
Sbjct: 1212 VEELTEQLEQFKRAKANL-DKNKQTLEKENADLAGELRVLGQAK----QEVEHKKKKLEA 1266
Query: 182 ENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRK 241
+ L+S E+ND + K NE ++ E L A +
Sbjct: 1267 QVQELQSKCSD-GERARAELNDKV---HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS 1322
Query: 242 QIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVER-VVQLEAAL 300
Q+ R S ++D+L E + K N+ER + L L
Sbjct: 1323 QLQDTQELLQEETRQKLNVSTKLRQLEEERNS-LQDQLDE-EMEAKQNLERHISTLNIQL 1380
Query: 301 EQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXX 360
++ + TV + F +E+ LTQ ++ + + + +LQ
Sbjct: 1381 SDSKKKLQDFASTV----EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQ-- 1434
Query: 361 XXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDL 420
+ + D+ ++ L ++ L + ++K++ + E+K + D R D
Sbjct: 1435 ------------ELDDLVVDLDNQRQL-VSNLEKKQRKFDQLLAEEKNISSKYADER-DR 1480
Query: 421 LESELRVKD-----LVRELDE----KESILETKQCVQKELE---STKTDLEHRKTEIEEY 468
E+E R K+ L R L+E KE + T + ++ E+E S+K D+ E+E+
Sbjct: 1481 AEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKS 1540
Query: 469 KRLLFEKGEE----IDELKSKL-STEKA 491
KR L + EE ++EL+ +L +TE A
Sbjct: 1541 KRALETQMEEMKTQLEELEDELQATEDA 1568
Score = 39.1 bits (87), Expect = 0.053
Identities = 48/225 (21%), Positives = 101/225 (44%), Gaps = 14/225 (6%)
Query: 405 EKKTLQENIDDLRTDLLESELRVKDLVRELDEKESIL-ETKQCVQKELESTKTDLEHRKT 463
+++ +Q D+L+ E + + ++ ++EL++K S L E K +Q++L++ +T+L
Sbjct: 857 QEEEMQAKEDELQKTK-ERQQKAENELKELEQKHSQLTEEKNLLQEQLQA-ETELY---A 911
Query: 464 EIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQ 523
E EE + L K +E++E+ ++ ++ E Q
Sbjct: 912 EAEEMRVRLAAKKQELEEILHEMEARLEEEE------DRGQQLQAERKKMAQQMLDLEEQ 965
Query: 524 MKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKEN 583
++ EE K Q+ ++ L D +++ Q +KL + K EE L T
Sbjct: 966 LEE--EEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLA 1023
Query: 584 EIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
E + +++T+ ++ E+++ +KEE+ + L KLE
Sbjct: 1024 EEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLE 1068
Score = 32.7 bits (71), Expect = 4.6
Identities = 29/96 (30%), Positives = 50/96 (52%), Gaps = 16/96 (16%)
Query: 564 LFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLL 623
L ++T+++EE +Q KE+E+++ E K E E+K L +K + NLL
Sbjct: 851 LLQVTRQEEE----MQAKEDELQKTKERQ-------QKAENELKELEQKHSQLTEEKNLL 899
Query: 624 HNKL----ELRNEADIDVIITLAKYKKSLTLVLEKM 655
+L EL EA+ ++ + LA K+ L +L +M
Sbjct: 900 QEQLQAETELYAEAE-EMRVRLAAKKQELEEILHEM 934
>AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY11)
(5'partial) protein.
Length = 1857
Score = 58.0 bits (134), Expect = 1e-07
Identities = 137/721 (19%), Positives = 278/721 (38%), Gaps = 68/721 (9%)
Query: 4 EELEIQQNQTDGCLYEDLNEQESITSESHKI-TKLKTVWQEKMVTFEKSKKELEDRQNQV 62
E+ Q + L E L + + +E+ ++ +L QE + + LE+ +++
Sbjct: 764 EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRG 823
Query: 63 MELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLD 122
+L A + ++M L +++ A + + K++ E ++ E + L +
Sbjct: 824 QQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ-LEKVTAEAKIKKL---EDEILVMDDQN 879
Query: 123 NKVTFDVNKLLNIPNSLVDKCEETLFKRKEII---NWFESLMSQEKGISTKTLTMKIKEF 179
NK++ + L + L E K K + N ES++S+ + K ++
Sbjct: 880 NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE-----LEVRLKKEEKS 934
Query: 180 NAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEM 239
E + LK L+ ++F ++I D+ + A M L + +EL AL+ L+ + A+
Sbjct: 935 RQELEKLKRKLEGDASDFHEQIADL---QAQIAELKMQLAKKEEELQAALARLDDEIAQK 991
Query: 240 R---KQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQL 296
K+I + H + K L LKT +E +
Sbjct: 992 NNALKKIRELEGHISDLQEDLDSERAARNKAEK-----QKRDLGEELEALKTELEDTLDS 1046
Query: 297 EAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELN-KLTQSIKDNTTHLEDIALAREK 355
A ++ R++ + E QE+ K Q++++ T LE A+
Sbjct: 1047 TATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKAN 1106
Query: 356 LQSXXXXXXXXXXXXSASYN---KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQEN 412
L + ++ ++++H+ A++ E++ K +D + L +
Sbjct: 1107 LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDK 1166
Query: 413 IDDLRTD-------LLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEI 465
+ L+ + L E+E + L +++ S L+ Q + +E K ++ + ++
Sbjct: 1167 VHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQL 1226
Query: 466 EEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMK 525
EE + L ++ +E E+++K + E+ I + E K
Sbjct: 1227 EEERNSLQDQLDE--EMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEAL----EEGKK 1280
Query: 526 SYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLF-----------ELTKRQEEY 574
+ +E+ NL Q + + A+D L N + Q+ D L L K+Q ++
Sbjct: 1281 RFQKEIENLTQQYEE--KAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKF 1338
Query: 575 DEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLN---------EKEEEHMNIINLLHN 625
D+ L ++N + + E +EKE K L+ E +EE +L
Sbjct: 1339 DQLLAEEKNISSKYADERDRAE--AEAREKETKALSLARALEEALEAKEELERTNKMLKA 1396
Query: 626 KLELRNEADIDV---IITLAKYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRTLRKNMSG 682
++E + DV + L K K++L +E+M L+ L L NM
Sbjct: 1397 EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA 1456
Query: 683 L 683
L
Sbjct: 1457 L 1457
Score = 50.8 bits (116), Expect = 2e-05
Identities = 47/226 (20%), Positives = 108/226 (47%), Gaps = 12/226 (5%)
Query: 276 KDRLSRAEHQLKTNVERVVQL--EAAL--EQARSESWSLERTVXXXXXXXXXXXEDFDQE 331
K+R +AE++LK ++ QL E L EQ ++E+ L ++ ++
Sbjct: 750 KERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEEMRVRLAAKKQELEEI 808
Query: 332 LNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNK-SIKDMKHEMNLNIA 390
L+++ +++ + + R+K+ A+ K ++ + E +
Sbjct: 809 LHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKL 868
Query: 391 K--LIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQ 448
+ ++ ++ + N +E+K L+E I DL T+L E E + K+L + ++ ES++ +
Sbjct: 869 EDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRL 928
Query: 449 KELESTKTDLEHRKTEIE----EYKRLLFEKGEEIDELKSKLSTEK 490
K+ E ++ +LE K ++E ++ + + +I ELK +L+ ++
Sbjct: 929 KKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 974
Score = 48.8 bits (111), Expect = 7e-05
Identities = 112/611 (18%), Positives = 235/611 (38%), Gaps = 37/611 (6%)
Query: 24 QESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQN---QVMELYASLRNTHRKMKLLG 80
QE + + TKL+ + +E+ ++ +E+E +QN + L L ++ +K++
Sbjct: 1210 QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFA 1269
Query: 81 QKVN-LPSAE---ELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIP 136
V L + + I N+ + E+ + K LD+ V D++ +
Sbjct: 1270 STVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV-DLDNQRQLV 1328
Query: 137 NSLVDK---CEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQL 193
++L K ++ L + K I + + + + + + T + A + L++ +
Sbjct: 1329 SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELE 1388
Query: 194 RT-EFLK-EINDII---DCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDH 248
RT + LK E+ D++ D + KN +E L+ + L + ++ TQ E+ ++ + +
Sbjct: 1389 RTNKMLKAEMEDLVSSKDDVGKNVHE---LEKSKRALETQMEEMKTQLEELEDELQATED 1445
Query: 249 H--RPYANRNXXXXXXXXXXXXXXXXSIMKDR-LSRAEHQLKTNVERVVQLEAALEQARS 305
R N + K R L R H+ +T +E + A A+
Sbjct: 1446 AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK 1505
Query: 306 ESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXX 365
+ + + E+ ++L KL +KD LED +R+++ +
Sbjct: 1506 KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK 1565
Query: 366 XXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESEL 425
A + +D+ K ++EK+ + EE + + L+ + E
Sbjct: 1566 KAKSLEADLMQLQEDLAAAERAR--KQADLEKE--ELAEELASSLSGRNALQDEKRRLEA 1621
Query: 426 RVKDLVRELDEKESILET------KQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI 479
R+ L EL+E++ +E K Q E S + E + E R E+ +
Sbjct: 1622 RIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNK- 1680
Query: 480 DELKSKL-STEKAIKD-IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQ 537
EL+SKL E A+K +++ KS ++ LK
Sbjct: 1681 -ELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEI 1739
Query: 538 ITQLR-EFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQE 596
+ Q+ E + + N + +L + EE +++ +++R ++ TE
Sbjct: 1740 LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESN 1799
Query: 597 HVLNKKEKEIK 607
+ ++ +K
Sbjct: 1800 EAMGREVNALK 1810
Score = 44.4 bits (100), Expect = 0.001
Identities = 115/646 (17%), Positives = 241/646 (37%), Gaps = 58/646 (8%)
Query: 20 DLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLL 79
D N+Q + +L+ + Q K E KK+LE QV EL + + R L
Sbjct: 1108 DKNKQTLEKENADLAGELRVLGQAKQEV-EHKKKKLEA---QVQELQSKCSDGERARAEL 1163
Query: 80 GQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSL 139
KV+ E + + + + ++L + + + + + LN+ L
Sbjct: 1164 NDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKL 1223
Query: 140 VDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLK-SSLDQLRTEFL 198
EE + ++ E+ + E+ IST + + + ++ +L++ + F
Sbjct: 1224 RQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ 1283
Query: 199 KEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXX 258
KEI ++ + A L+ L L DL R+ + + + + ++
Sbjct: 1284 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQ--- 1340
Query: 259 XXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERT---VX 315
S D RAE + + + + L ALE+A LERT +
Sbjct: 1341 -----LLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLK 1395
Query: 316 XXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKL----QSXXXXXXXXXXXXS 371
+D + +++L +S + T +E++ E+L Q+
Sbjct: 1396 AEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ 1455
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKK---YNDSIEE-----------KKTLQENIDDLR 417
A + +D++ N K +++++ Y +E+ KK L+ ++ DL
Sbjct: 1456 ALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLE 1515
Query: 418 TD--------------LLESELRVKDLVRELDE----KESILETKQCVQKELESTKTDLE 459
L + + ++KD REL++ ++ I T + +K+ +S + DL
Sbjct: 1516 LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLM 1575
Query: 460 HRKTEIEEYKRLL----FEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXX 515
+ ++ +R EK E +EL S LS A++D
Sbjct: 1576 QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQG 1635
Query: 516 XXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYD 575
+++ ++ L N++ R A N + + Q ++ +L + +
Sbjct: 1636 NMEAMSDRVRKATQQAEQLSNELATERS-TAQKNESARQQLERQNKELRSKLHEMEGAVK 1694
Query: 576 EKLQTKENEIKRLVESMTEQ-EHVLNKKEKEIKMLNEKEEEHMNII 620
K ++ ++ + + EQ E +K+ K L +K+++ I+
Sbjct: 1695 SKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEIL 1740
Score = 44.0 bits (99), Expect = 0.002
Identities = 103/508 (20%), Positives = 199/508 (39%), Gaps = 52/508 (10%)
Query: 2 KQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQ 61
K+EEL+ + D + + N + I I+ L+ + K++K+ D +
Sbjct: 973 KEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEE 1032
Query: 62 VMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTL 121
+ L L +T + + L + E + + K E+ A + +H+
Sbjct: 1033 LEALKTELEDT---LDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA 1089
Query: 122 DNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNA 181
++T + + +L DK ++TL K + ++ Q K + + K K+ A
Sbjct: 1090 VEELTEQLEQFKRAKANL-DKNKQTLEKENADLAGELRVLGQAK----QEVEHKKKKLEA 1144
Query: 182 ENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRK 241
+ L+S E+ND + K NE ++ E L A +
Sbjct: 1145 QVQELQSKCSD-GERARAELNDKV---HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS 1200
Query: 242 QIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVER-VVQLEAAL 300
Q+ R S ++D+L E + K N+ER + L L
Sbjct: 1201 QLQDTQELLQEETRQKLNVSTKLRQLEEERNS-LQDQLDE-EMEAKQNLERHISTLNIQL 1258
Query: 301 EQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXX 360
++ + TV + F +E+ LTQ ++ + + + +LQ
Sbjct: 1259 SDSKKKLQDFASTV----EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQ-- 1312
Query: 361 XXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDL 420
+ + D+ ++ L ++ L + ++K++ + E+K + D R D
Sbjct: 1313 ------------ELDDLVVDLDNQRQL-VSNLEKKQRKFDQLLAEEKNISSKYADER-DR 1358
Query: 421 LESELRVKD-----LVRELDE----KESILETKQCVQKELE---STKTDLEHRKTEIEEY 468
E+E R K+ L R L+E KE + T + ++ E+E S+K D+ E+E+
Sbjct: 1359 AEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKS 1418
Query: 469 KRLLFEKGEE----IDELKSKL-STEKA 491
KR L + EE ++EL+ +L +TE A
Sbjct: 1419 KRALETQMEEMKTQLEELEDELQATEDA 1446
Score = 39.1 bits (87), Expect = 0.053
Identities = 48/225 (21%), Positives = 101/225 (44%), Gaps = 14/225 (6%)
Query: 405 EKKTLQENIDDLRTDLLESELRVKDLVRELDEKESIL-ETKQCVQKELESTKTDLEHRKT 463
+++ +Q D+L+ E + + ++ ++EL++K S L E K +Q++L++ +T+L
Sbjct: 735 QEEEMQAKEDELQKTK-ERQQKAENELKELEQKHSQLTEEKNLLQEQLQA-ETELY---A 789
Query: 464 EIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQ 523
E EE + L K +E++E+ ++ ++ E Q
Sbjct: 790 EAEEMRVRLAAKKQELEEILHEMEARLEEEE------DRGQQLQAERKKMAQQMLDLEEQ 843
Query: 524 MKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKEN 583
++ EE K Q+ ++ L D +++ Q +KL + K EE L T
Sbjct: 844 LEE--EEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLA 901
Query: 584 EIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
E + +++T+ ++ E+++ +KEE+ + L KLE
Sbjct: 902 EEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLE 946
Score = 32.7 bits (71), Expect = 4.6
Identities = 29/96 (30%), Positives = 50/96 (52%), Gaps = 16/96 (16%)
Query: 564 LFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLL 623
L ++T+++EE +Q KE+E+++ E K E E+K L +K + NLL
Sbjct: 729 LLQVTRQEEE----MQAKEDELQKTKERQ-------QKAENELKELEQKHSQLTEEKNLL 777
Query: 624 HNKL----ELRNEADIDVIITLAKYKKSLTLVLEKM 655
+L EL EA+ ++ + LA K+ L +L +M
Sbjct: 778 QEQLQAETELYAEAE-EMRVRLAAKKQELEEILHEM 812
>AB053468-1|BAC54107.1| 992|Homo sapiens ELKS beta protein.
Length = 992
Score = 58.0 bits (134), Expect = 1e-07
Identities = 116/648 (17%), Positives = 256/648 (39%), Gaps = 64/648 (9%)
Query: 3 QEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQV 62
++++E+++++ L +N ++ S K + + +T K + + +NQ
Sbjct: 169 RKDVEVKESK----LSSSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQH 224
Query: 63 MEL-YASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTL 121
M++ +L++ R + L Q S+ VA+L+ E +L A E +A E
Sbjct: 225 MQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKE---- 280
Query: 122 DNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTL------TMK 175
F + K L ++ ++TL R E I ++ Q KG+S K T +
Sbjct: 281 ----LFLLRKTLEEMELRIETQKQTLNARDESIKKLLEML-QSKGLSAKATEEDHERTRR 335
Query: 176 IKEFNAENDLLKSSLDQ-------LRTEFLKEINDIIDCLRKNANETMALQLRTKELSCA 228
+ E L+S L+Q LR E + + D + A +T+ ++++ ++S
Sbjct: 336 LAEAEMHVHHLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTV-IEMKDSKISSM 394
Query: 229 LSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKT 288
L E++ +G + MK+++ + + +L
Sbjct: 395 ERGLRDLEEEIQMLKSNGA-----LSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSR 449
Query: 289 NVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXED---FDQELNKLTQSIKDNTTH 345
++ L+ LE ++ ++ + + E++ L +++ T
Sbjct: 450 KDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETM 509
Query: 346 LEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH-EMNLNIAKLIEIEKKYNDSIE 404
L ++ Q K + D+K ++N+ K+ ++++ D +
Sbjct: 510 LN-----KKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEK 564
Query: 405 EKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTE 464
+ +L+E + L+ D ++ + L L EKE +E + E D ++ E
Sbjct: 565 QMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLK------EQRDRDEREKQEE 618
Query: 465 IEEYKRLLFEKGEEIDELKSKLSTEKA-IKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQ 523
I+ YK+ L + E++ L+ LS ++A + D+ E
Sbjct: 619 IDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTL----EIA 674
Query: 524 MKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKEN 583
++ EE + +++Q+ + E A + + D++ L + Y ++ +
Sbjct: 675 LEQKKEECLKMESQLKKAHE-AALE-----ARASPEMSDRIQHLEREITRYKDESSKAQA 728
Query: 584 EIKRLVESMTEQEHVLNKKEKEIKML-----NEKEEEHMNIINLLHNK 626
E+ RL+E + E E+ N K+K+I L + ++++ + NL H +
Sbjct: 729 EVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKE 776
Score = 48.8 bits (111), Expect = 7e-05
Identities = 68/345 (19%), Positives = 151/345 (43%), Gaps = 26/345 (7%)
Query: 150 RKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLR 209
+K+I N E L +EK +S+ L ++K A+ ++L L E L E I+ L+
Sbjct: 549 QKKIENLQEQLRDKEKQMSS--LKERVKSLQADTTNTDTALTTLE-EALAEKERTIERLK 605
Query: 210 KNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXX 269
+ + + + +E+ DL ++ + + + GD + +
Sbjct: 606 EQRDRDE--REKQEEIDNYKKDL--KDLKEKVSLLQGD----LSEKEASLLDLKEHASSL 657
Query: 270 XXXSIMKD-RLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDF 328
+ KD RL E L+ E +++E+ L++A + LE +
Sbjct: 658 ASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAA--LE---ARASPEMSDRIQHL 712
Query: 329 DQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEM-NL 387
++E+ + ++ + +++++ + ++ +KD ++ NL
Sbjct: 713 EREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANL 772
Query: 388 NIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDE--KESILET-- 443
+ +E +KK +EE + ++N++D L +S + D + EL+E +ES+ T
Sbjct: 773 KHKEQVE-KKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAE 831
Query: 444 KQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLST 488
++ V + ES +T+ E ++EE + + +E++ +K+KLS+
Sbjct: 832 REMVLAQEESARTNAE---KQVEELLMAMEKVKQELESMKAKLSS 873
Score = 36.3 bits (80), Expect = 0.37
Identities = 48/248 (19%), Positives = 104/248 (41%), Gaps = 11/248 (4%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENID--DLRTDLLESELRVKDLVRELDEKESILETKQCVQ 448
KL + +++DS + + L+E++ + R +L++E V L L+EKE++L K
Sbjct: 460 KLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTE--VDALRLRLEEKETMLNKK---T 514
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXX 508
K+++ + + EI + K +L K +++ L+ K+ +++
Sbjct: 515 KQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIEN---LQEQLRDKEKQMSSLKE 571
Query: 509 XXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELT 568
++ + + E L + I +L+E D + N ++D L +L
Sbjct: 572 RVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKD-LKDLK 630
Query: 569 KRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
++ L KE + L E + KK+ +K L E+ + ++L+
Sbjct: 631 EKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLK 690
Query: 629 LRNEADID 636
+EA ++
Sbjct: 691 KAHEAALE 698
>AB029004-1|BAA83033.2| 1003|Homo sapiens KIAA1081 protein protein.
Length = 1003
Score = 58.0 bits (134), Expect = 1e-07
Identities = 116/648 (17%), Positives = 256/648 (39%), Gaps = 64/648 (9%)
Query: 3 QEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQV 62
++++E+++++ L +N ++ S K + + +T K + + +NQ
Sbjct: 180 RKDVEVKESK----LSSSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQH 235
Query: 63 MEL-YASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTL 121
M++ +L++ R + L Q S+ VA+L+ E +L A E +A E
Sbjct: 236 MQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKE---- 291
Query: 122 DNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTL------TMK 175
F + K L ++ ++TL R E I ++ Q KG+S K T +
Sbjct: 292 ----LFLLRKTLEEMELRIETQKQTLNARDESIKKLLEML-QSKGLSAKATEEDHERTRR 346
Query: 176 IKEFNAENDLLKSSLDQ-------LRTEFLKEINDIIDCLRKNANETMALQLRTKELSCA 228
+ E L+S L+Q LR E + + D + A +T+ ++++ ++S
Sbjct: 347 LAEAEMHVHHLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTV-IEMKDSKISSM 405
Query: 229 LSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKT 288
L E++ +G + MK+++ + + +L
Sbjct: 406 ERGLRDLEEEIQMLKSNGA-----LSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSR 460
Query: 289 NVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXED---FDQELNKLTQSIKDNTTH 345
++ L+ LE ++ ++ + + E++ L +++ T
Sbjct: 461 KDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETM 520
Query: 346 LEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH-EMNLNIAKLIEIEKKYNDSIE 404
L ++ Q K + D+K ++N+ K+ ++++ D +
Sbjct: 521 LN-----KKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEK 575
Query: 405 EKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTE 464
+ +L+E + L+ D ++ + L L EKE +E + E D ++ E
Sbjct: 576 QMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLK------EQRDRDEREKQEE 629
Query: 465 IEEYKRLLFEKGEEIDELKSKLSTEKA-IKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQ 523
I+ YK+ L + E++ L+ LS ++A + D+ E
Sbjct: 630 IDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTL----EIA 685
Query: 524 MKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKEN 583
++ EE + +++Q+ + E A + + D++ L + Y ++ +
Sbjct: 686 LEQKKEECLKMESQLKKAHE-AALE-----ARASPEMSDRIQHLEREITRYKDESSKAQA 739
Query: 584 EIKRLVESMTEQEHVLNKKEKEIKML-----NEKEEEHMNIINLLHNK 626
E+ RL+E + E E+ N K+K+I L + ++++ + NL H +
Sbjct: 740 EVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKE 787
Score = 48.8 bits (111), Expect = 7e-05
Identities = 68/345 (19%), Positives = 151/345 (43%), Gaps = 26/345 (7%)
Query: 150 RKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLR 209
+K+I N E L +EK +S+ L ++K A+ ++L L E L E I+ L+
Sbjct: 560 QKKIENLQEQLRDKEKQMSS--LKERVKSLQADTTNTDTALTTLE-EALAEKERTIERLK 616
Query: 210 KNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXX 269
+ + + + +E+ DL ++ + + + GD + +
Sbjct: 617 EQRDRDE--REKQEEIDNYKKDL--KDLKEKVSLLQGD----LSEKEASLLDLKEHASSL 668
Query: 270 XXXSIMKD-RLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDF 328
+ KD RL E L+ E +++E+ L++A + LE +
Sbjct: 669 ASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAA--LE---ARASPEMSDRIQHL 723
Query: 329 DQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEM-NL 387
++E+ + ++ + +++++ + ++ +KD ++ NL
Sbjct: 724 EREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANL 783
Query: 388 NIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDE--KESILET-- 443
+ +E +KK +EE + ++N++D L +S + D + EL+E +ES+ T
Sbjct: 784 KHKEQVE-KKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAE 842
Query: 444 KQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLST 488
++ V + ES +T+ E ++EE + + +E++ +K+KLS+
Sbjct: 843 REMVLAQEESARTNAE---KQVEELLMAMEKVKQELESMKAKLSS 884
Score = 36.3 bits (80), Expect = 0.37
Identities = 48/248 (19%), Positives = 104/248 (41%), Gaps = 11/248 (4%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENID--DLRTDLLESELRVKDLVRELDEKESILETKQCVQ 448
KL + +++DS + + L+E++ + R +L++E V L L+EKE++L K
Sbjct: 471 KLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTE--VDALRLRLEEKETMLNKK---T 525
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXX 508
K+++ + + EI + K +L K +++ L+ K+ +++
Sbjct: 526 KQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIEN---LQEQLRDKEKQMSSLKE 582
Query: 509 XXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELT 568
++ + + E L + I +L+E D + N ++D L +L
Sbjct: 583 RVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKD-LKDLK 641
Query: 569 KRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
++ L KE + L E + KK+ +K L E+ + ++L+
Sbjct: 642 EKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLK 701
Query: 629 LRNEADID 636
+EA ++
Sbjct: 702 KAHEAALE 709
>AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein.
Length = 1984
Score = 58.0 bits (134), Expect = 1e-07
Identities = 137/721 (19%), Positives = 278/721 (38%), Gaps = 68/721 (9%)
Query: 4 EELEIQQNQTDGCLYEDLNEQESITSESHKI-TKLKTVWQEKMVTFEKSKKELEDRQNQV 62
E+ Q + L E L + + +E+ ++ +L QE + + LE+ +++
Sbjct: 891 EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRG 950
Query: 63 MELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLD 122
+L A + ++M L +++ A + + K++ E ++ E + L +
Sbjct: 951 QQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ-LEKVTAEAKIKKL---EDEILVMDDQN 1006
Query: 123 NKVTFDVNKLLNIPNSLVDKCEETLFKRKEII---NWFESLMSQEKGISTKTLTMKIKEF 179
NK++ + L + L E K K + N ES++S+ + K ++
Sbjct: 1007 NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE-----LEVRLKKEEKS 1061
Query: 180 NAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEM 239
E + LK L+ ++F ++I D+ + A M L + +EL AL+ L+ + A+
Sbjct: 1062 RQELEKLKRKLEGDASDFHEQIADL---QAQIAELKMQLAKKEEELQAALARLDDEIAQK 1118
Query: 240 R---KQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQL 296
K+I + H + K L LKT +E +
Sbjct: 1119 NNALKKIRELEGHISDLQEDLDSERAARNKAEK-----QKRDLGEELEALKTELEDTLDS 1173
Query: 297 EAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELN-KLTQSIKDNTTHLEDIALAREK 355
A ++ R++ + E QE+ K Q++++ T LE A+
Sbjct: 1174 TATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKAN 1233
Query: 356 LQSXXXXXXXXXXXXSASYN---KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQEN 412
L + ++ ++++H+ A++ E++ K +D + L +
Sbjct: 1234 LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDK 1293
Query: 413 IDDLRTD-------LLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEI 465
+ L+ + L E+E + L +++ S L+ Q + +E K ++ + ++
Sbjct: 1294 VHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQL 1353
Query: 466 EEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMK 525
EE + L ++ +E E+++K + E+ I + E K
Sbjct: 1354 EEERNSLQDQLDE--EMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEAL----EEGKK 1407
Query: 526 SYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLF-----------ELTKRQEEY 574
+ +E+ NL Q + + A+D L N + Q+ D L L K+Q ++
Sbjct: 1408 RFQKEIENLTQQYEE--KAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKF 1465
Query: 575 DEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLN---------EKEEEHMNIINLLHN 625
D+ L ++N + + E +EKE K L+ E +EE +L
Sbjct: 1466 DQLLAEEKNISSKYADERDRAE--AEAREKETKALSLARALEEALEAKEELERTNKMLKA 1523
Query: 626 KLELRNEADIDV---IITLAKYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRTLRKNMSG 682
++E + DV + L K K++L +E+M L+ L L NM
Sbjct: 1524 EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA 1583
Query: 683 L 683
L
Sbjct: 1584 L 1584
Score = 50.8 bits (116), Expect = 2e-05
Identities = 47/226 (20%), Positives = 108/226 (47%), Gaps = 12/226 (5%)
Query: 276 KDRLSRAEHQLKTNVERVVQL--EAAL--EQARSESWSLERTVXXXXXXXXXXXEDFDQE 331
K+R +AE++LK ++ QL E L EQ ++E+ L ++ ++
Sbjct: 877 KERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEEMRVRLAAKKQELEEI 935
Query: 332 LNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNK-SIKDMKHEMNLNIA 390
L+++ +++ + + R+K+ A+ K ++ + E +
Sbjct: 936 LHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKL 995
Query: 391 K--LIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQ 448
+ ++ ++ + N +E+K L+E I DL T+L E E + K+L + ++ ES++ +
Sbjct: 996 EDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRL 1055
Query: 449 KELESTKTDLEHRKTEIE----EYKRLLFEKGEEIDELKSKLSTEK 490
K+ E ++ +LE K ++E ++ + + +I ELK +L+ ++
Sbjct: 1056 KKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1101
Score = 48.8 bits (111), Expect = 7e-05
Identities = 112/611 (18%), Positives = 235/611 (38%), Gaps = 37/611 (6%)
Query: 24 QESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQN---QVMELYASLRNTHRKMKLLG 80
QE + + TKL+ + +E+ ++ +E+E +QN + L L ++ +K++
Sbjct: 1337 QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFA 1396
Query: 81 QKVN-LPSAE---ELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIP 136
V L + + I N+ + E+ + K LD+ V D++ +
Sbjct: 1397 STVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV-DLDNQRQLV 1455
Query: 137 NSLVDK---CEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQL 193
++L K ++ L + K I + + + + + + T + A + L++ +
Sbjct: 1456 SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELE 1515
Query: 194 RT-EFLK-EINDII---DCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDH 248
RT + LK E+ D++ D + KN +E L+ + L + ++ TQ E+ ++ + +
Sbjct: 1516 RTNKMLKAEMEDLVSSKDDVGKNVHE---LEKSKRALETQMEEMKTQLEELEDELQATED 1572
Query: 249 H--RPYANRNXXXXXXXXXXXXXXXXSIMKDR-LSRAEHQLKTNVERVVQLEAALEQARS 305
R N + K R L R H+ +T +E + A A+
Sbjct: 1573 AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK 1632
Query: 306 ESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXX 365
+ + + E+ ++L KL +KD LED +R+++ +
Sbjct: 1633 KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK 1692
Query: 366 XXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESEL 425
A + +D+ K ++EK+ + EE + + L+ + E
Sbjct: 1693 KAKSLEADLMQLQEDLAAAERAR--KQADLEKE--ELAEELASSLSGRNALQDEKRRLEA 1748
Query: 426 RVKDLVRELDEKESILET------KQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI 479
R+ L EL+E++ +E K Q E S + E + E R E+ +
Sbjct: 1749 RIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNK- 1807
Query: 480 DELKSKL-STEKAIKD-IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQ 537
EL+SKL E A+K +++ KS ++ LK
Sbjct: 1808 -ELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEI 1866
Query: 538 ITQLR-EFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQE 596
+ Q+ E + + N + +L + EE +++ +++R ++ TE
Sbjct: 1867 LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESN 1926
Query: 597 HVLNKKEKEIK 607
+ ++ +K
Sbjct: 1927 EAMGREVNALK 1937
Score = 44.4 bits (100), Expect = 0.001
Identities = 115/646 (17%), Positives = 241/646 (37%), Gaps = 58/646 (8%)
Query: 20 DLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLL 79
D N+Q + +L+ + Q K E KK+LE QV EL + + R L
Sbjct: 1235 DKNKQTLEKENADLAGELRVLGQAKQEV-EHKKKKLEA---QVQELQSKCSDGERARAEL 1290
Query: 80 GQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSL 139
KV+ E + + + + ++L + + + + + LN+ L
Sbjct: 1291 NDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKL 1350
Query: 140 VDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLK-SSLDQLRTEFL 198
EE + ++ E+ + E+ IST + + + ++ +L++ + F
Sbjct: 1351 RQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ 1410
Query: 199 KEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXX 258
KEI ++ + A L+ L L DL R+ + + + + ++
Sbjct: 1411 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQ--- 1467
Query: 259 XXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERT---VX 315
S D RAE + + + + L ALE+A LERT +
Sbjct: 1468 -----LLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLK 1522
Query: 316 XXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKL----QSXXXXXXXXXXXXS 371
+D + +++L +S + T +E++ E+L Q+
Sbjct: 1523 AEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ 1582
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKK---YNDSIEE-----------KKTLQENIDDLR 417
A + +D++ N K +++++ Y +E+ KK L+ ++ DL
Sbjct: 1583 ALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLE 1642
Query: 418 TD--------------LLESELRVKDLVRELDE----KESILETKQCVQKELESTKTDLE 459
L + + ++KD REL++ ++ I T + +K+ +S + DL
Sbjct: 1643 LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLM 1702
Query: 460 HRKTEIEEYKRLL----FEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXX 515
+ ++ +R EK E +EL S LS A++D
Sbjct: 1703 QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQG 1762
Query: 516 XXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYD 575
+++ ++ L N++ R A N + + Q ++ +L + +
Sbjct: 1763 NMEAMSDRVRKATQQAEQLSNELATERS-TAQKNESARQQLERQNKELRSKLHEMEGAVK 1821
Query: 576 EKLQTKENEIKRLVESMTEQ-EHVLNKKEKEIKMLNEKEEEHMNII 620
K ++ ++ + + EQ E +K+ K L +K+++ I+
Sbjct: 1822 SKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEIL 1867
Score = 44.0 bits (99), Expect = 0.002
Identities = 103/508 (20%), Positives = 199/508 (39%), Gaps = 52/508 (10%)
Query: 2 KQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQ 61
K+EEL+ + D + + N + I I+ L+ + K++K+ D +
Sbjct: 1100 KEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEE 1159
Query: 62 VMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTL 121
+ L L +T + + L + E + + K E+ A + +H+
Sbjct: 1160 LEALKTELEDT---LDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA 1216
Query: 122 DNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNA 181
++T + + +L DK ++TL K + ++ Q K + + K K+ A
Sbjct: 1217 VEELTEQLEQFKRAKANL-DKNKQTLEKENADLAGELRVLGQAK----QEVEHKKKKLEA 1271
Query: 182 ENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRK 241
+ L+S E+ND + K NE ++ E L A +
Sbjct: 1272 QVQELQSKCSD-GERARAELNDKV---HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS 1327
Query: 242 QIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVER-VVQLEAAL 300
Q+ R S ++D+L E + K N+ER + L L
Sbjct: 1328 QLQDTQELLQEETRQKLNVSTKLRQLEEERNS-LQDQLDE-EMEAKQNLERHISTLNIQL 1385
Query: 301 EQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXX 360
++ + TV + F +E+ LTQ ++ + + + +LQ
Sbjct: 1386 SDSKKKLQDFASTV----EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQ-- 1439
Query: 361 XXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDL 420
+ + D+ ++ L ++ L + ++K++ + E+K + D R D
Sbjct: 1440 ------------ELDDLVVDLDNQRQL-VSNLEKKQRKFDQLLAEEKNISSKYADER-DR 1485
Query: 421 LESELRVKD-----LVRELDE----KESILETKQCVQKELE---STKTDLEHRKTEIEEY 468
E+E R K+ L R L+E KE + T + ++ E+E S+K D+ E+E+
Sbjct: 1486 AEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKS 1545
Query: 469 KRLLFEKGEE----IDELKSKL-STEKA 491
KR L + EE ++EL+ +L +TE A
Sbjct: 1546 KRALETQMEEMKTQLEELEDELQATEDA 1573
Score = 39.1 bits (87), Expect = 0.053
Identities = 48/225 (21%), Positives = 101/225 (44%), Gaps = 14/225 (6%)
Query: 405 EKKTLQENIDDLRTDLLESELRVKDLVRELDEKESIL-ETKQCVQKELESTKTDLEHRKT 463
+++ +Q D+L+ E + + ++ ++EL++K S L E K +Q++L++ +T+L
Sbjct: 862 QEEEMQAKEDELQKTK-ERQQKAENELKELEQKHSQLTEEKNLLQEQLQA-ETELY---A 916
Query: 464 EIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQ 523
E EE + L K +E++E+ ++ ++ E Q
Sbjct: 917 EAEEMRVRLAAKKQELEEILHEMEARLEEEE------DRGQQLQAERKKMAQQMLDLEEQ 970
Query: 524 MKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKEN 583
++ EE K Q+ ++ L D +++ Q +KL + K EE L T
Sbjct: 971 LEE--EEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLA 1028
Query: 584 EIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
E + +++T+ ++ E+++ +KEE+ + L KLE
Sbjct: 1029 EEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLE 1073
Score = 32.7 bits (71), Expect = 4.6
Identities = 29/96 (30%), Positives = 50/96 (52%), Gaps = 16/96 (16%)
Query: 564 LFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLL 623
L ++T+++EE +Q KE+E+++ E K E E+K L +K + NLL
Sbjct: 856 LLQVTRQEEE----MQAKEDELQKTKERQ-------QKAENELKELEQKHSQLTEEKNLL 904
Query: 624 HNKL----ELRNEADIDVIITLAKYKKSLTLVLEKM 655
+L EL EA+ ++ + LA K+ L +L +M
Sbjct: 905 QEQLQAETELYAEAE-EMRVRLAAKKQELEEILHEM 939
>AB015617-1|BAA88763.1| 948|Homo sapiens ELKS protein.
Length = 948
Score = 58.0 bits (134), Expect = 1e-07
Identities = 116/648 (17%), Positives = 256/648 (39%), Gaps = 64/648 (9%)
Query: 3 QEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQV 62
++++E+++++ L +N ++ S K + + +T K + + +NQ
Sbjct: 169 RKDVEVKESK----LSSSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQH 224
Query: 63 MEL-YASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTL 121
M++ +L++ R + L Q S+ VA+L+ E +L A E +A E
Sbjct: 225 MQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKE---- 280
Query: 122 DNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTL------TMK 175
F + K L ++ ++TL R E I ++ Q KG+S K T +
Sbjct: 281 ----LFLLRKTLEEMELRIETQKQTLNARDESIKKLLEML-QSKGLSAKATEEDHERTRR 335
Query: 176 IKEFNAENDLLKSSLDQ-------LRTEFLKEINDIIDCLRKNANETMALQLRTKELSCA 228
+ E L+S L+Q LR E + + D + A +T+ ++++ ++S
Sbjct: 336 LAEAEMHVHHLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTV-IEMKDSKISSM 394
Query: 229 LSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKT 288
L E++ +G + MK+++ + + +L
Sbjct: 395 ERGLRDLEEEIQMLKSNGA-----LSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSR 449
Query: 289 NVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXED---FDQELNKLTQSIKDNTTH 345
++ L+ LE ++ ++ + + E++ L +++ T
Sbjct: 450 KDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETM 509
Query: 346 LEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH-EMNLNIAKLIEIEKKYNDSIE 404
L ++ Q K + D+K ++N+ K+ ++++ D +
Sbjct: 510 LN-----KKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEK 564
Query: 405 EKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTE 464
+ +L+E + L+ D ++ + L L EKE +E + E D ++ E
Sbjct: 565 QMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLK------EQRDRDEREKQEE 618
Query: 465 IEEYKRLLFEKGEEIDELKSKLSTEKA-IKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQ 523
I+ YK+ L + E++ L+ LS ++A + D+ E
Sbjct: 619 IDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTL----EIA 674
Query: 524 MKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKEN 583
++ EE + +++Q+ + E A + + D++ L + Y ++ +
Sbjct: 675 LEQKKEECLKMESQLKKAHE-AALE-----ARASPEMSDRIQHLEREITRYKDESSKAQA 728
Query: 584 EIKRLVESMTEQEHVLNKKEKEIKML-----NEKEEEHMNIINLLHNK 626
E+ RL+E + E E+ N K+K+I L + ++++ + NL H +
Sbjct: 729 EVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKE 776
Score = 48.0 bits (109), Expect = 1e-04
Identities = 115/608 (18%), Positives = 236/608 (38%), Gaps = 56/608 (9%)
Query: 30 ESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAE 89
++ ++ L+ +E + E K+ L R + +L L++ K L K E
Sbjct: 277 QAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQS-----KGLSAKATEEDHE 331
Query: 90 ELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFK 149
+ A++ L L E K E+S L ++ + N P+S K +T+ +
Sbjct: 332 RTRRLAEAEMHVHHLESLL---EQKEKENSMLREEMH---RRFENAPDSAKTKALQTVIE 385
Query: 150 RKE--IINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLK-EINDIID 206
K+ I + L E+ I + E ++ + + + ++F+K +I +
Sbjct: 386 MKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQ 445
Query: 207 CLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXX 266
L + E +ALQ + + L+ SD + Q+ E+ K+ + R +
Sbjct: 446 ELSRKDTELLALQTKLETLTNQFSD-SKQHIEVLKESLTAKEQRAAILQTEVDALRLRLE 504
Query: 267 XXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXE 326
+ ++ + T + L+ L+ + L++ + +
Sbjct: 505 EKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEK 564
Query: 327 DFDQELNKLTQSIKDNTTHLE------DIALAR-----EKLQSXXXXXXXXXXXXSASYN 375
L + +S++ +TT+ + + ALA E+L+ +Y
Sbjct: 565 QMSS-LKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYK 623
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD 435
K +KD+K +++L L E E D L+E+ L + L+ + R+K L L+
Sbjct: 624 KDLKDLKEKVSLLQGDLSEKEASLLD-------LKEHASSLASSGLKKDSRLKTLEIALE 676
Query: 436 E-KESILETKQCVQKELEST---------KTDLEHRKTEIEEYKRLLFEKGEEIDELKSK 485
+ KE L+ + ++K E+ ++H + EI YK + E+D L
Sbjct: 677 QKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRL--- 733
Query: 486 LSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREF- 544
L K +++ + + +K ++E + K L E
Sbjct: 734 LEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLK--HKEQVEKKKSAQMLEEAR 791
Query: 545 GAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQE-HVLNKKE 603
DNLND + Q+ ++ EL E+ ++L++ + ++ +S+ E+E H+ N +
Sbjct: 792 RREDNLND-----SSQQLQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRA 846
Query: 604 KEIKMLNE 611
+ K L E
Sbjct: 847 ERRKHLEE 854
Score = 36.3 bits (80), Expect = 0.37
Identities = 48/248 (19%), Positives = 104/248 (41%), Gaps = 11/248 (4%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENID--DLRTDLLESELRVKDLVRELDEKESILETKQCVQ 448
KL + +++DS + + L+E++ + R +L++E V L L+EKE++L K
Sbjct: 460 KLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTE--VDALRLRLEEKETMLNKK---T 514
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXX 508
K+++ + + EI + K +L K +++ L+ K+ +++
Sbjct: 515 KQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIEN---LQEQLRDKEKQMSSLKE 571
Query: 509 XXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELT 568
++ + + E L + I +L+E D + N ++D L +L
Sbjct: 572 RVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKD-LKDLK 630
Query: 569 KRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
++ L KE + L E + KK+ +K L E+ + ++L+
Sbjct: 631 EKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLK 690
Query: 629 LRNEADID 636
+EA ++
Sbjct: 691 KAHEAALE 698
>BC126409-1|AAI26410.1| 1941|Homo sapiens myosin, heavy chain 2,
skeletal muscle, adult protein.
Length = 1941
Score = 57.2 bits (132), Expect = 2e-07
Identities = 80/462 (17%), Positives = 181/462 (39%), Gaps = 24/462 (5%)
Query: 164 EKGIST-KTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRT 222
EK ++T K KIK+ A+++ + L++ LKE ND+ ++ A + R
Sbjct: 852 EKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERC 911
Query: 223 KELSCALSDLNTQNAEMRKQIHSGDHHRPY--ANRNXXXXXXXXXXXXXXXXSIMKDRLS 280
+L L + E+ ++ + A + + ++
Sbjct: 912 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 971
Query: 281 RAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQS-- 338
+ +H + V+ + + A L++ ++ ++ + + + ++N LT++
Sbjct: 972 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKI 1031
Query: 339 -IKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEK 397
++ LE +KL+ +SI D+++E ++++
Sbjct: 1032 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ-------QLDE 1084
Query: 398 KYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTD 457
K E LQ I+D + ++ + ++K+L ++E E +E ++ + + E ++D
Sbjct: 1085 KLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSD 1144
Query: 458 LEHRKTEIEEYKRLLFEKGEEID---ELKSKLSTE--KAIKDIXXXXXXXXXXXXXXXXX 512
L E+EE L E G E+ K E K +D+
Sbjct: 1145 LSR---ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKK 1201
Query: 513 XXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQE 572
Q+ + L+ + ++++ D+L +++ + L ++ + E
Sbjct: 1202 HADSVAELGEQIDNLQRVKQKLEKEKSEMKM--EIDDLASNVETVSKAKGNLEKMCRTLE 1259
Query: 573 EYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEI-KMLNEKE 613
+ +L++KE E +RL+ +T Q L + E + L+EKE
Sbjct: 1260 DQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKE 1301
Score = 48.8 bits (111), Expect = 7e-05
Identities = 70/368 (19%), Positives = 154/368 (41%), Gaps = 25/368 (6%)
Query: 277 DRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLT 336
D+L + + QL+ ++ V + E+ +E + +R + +D + L K+
Sbjct: 912 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 971
Query: 337 QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHE---MNLNIAKLI 393
+ ++++ L ++ +++ D++ E +N I
Sbjct: 972 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKI 1031
Query: 394 EIEKKYND---SIEEKKTLQENID----DLRTDLLESELRVKDLVRELDEKESILETKQC 446
++E++ +D S+E++K L+ +++ L DL ++ + D+ E + + L+ K+
Sbjct: 1032 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEF 1091
Query: 447 VQKELESTKTDLE----HRKTEIEEYKRLLFEKGEEID-ELKSKLSTEKAIKDIXXXXXX 501
L+S D + + +I+E + + E EEI+ E S+ EK D+
Sbjct: 1092 EISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEE 1151
Query: 502 XXXXXXXXXXXXXXXXXX---RESQMKSYYEEL--MNLKNQITQ--LREFGAFDNLNDVG 554
RE++ + +L L+++ T LR+ A D++ ++G
Sbjct: 1152 ISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHA-DSVAELG 1210
Query: 555 NMI-NQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKE 613
I N QR K +L K + E ++ + ++ + ++ E + E ++ L KE
Sbjct: 1211 EQIDNLQRVKQ-KLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKE 1269
Query: 614 EEHMNIIN 621
EE +IN
Sbjct: 1270 EEQQRLIN 1277
Score = 45.6 bits (103), Expect = 6e-04
Identities = 51/266 (19%), Positives = 109/266 (40%), Gaps = 15/266 (5%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLV 431
A+ + + +K E+ + AK E+E+K ++EK LQ + L ++E R L+
Sbjct: 856 ATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLI 915
Query: 432 R-ELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDEL-------- 482
+ ++ + I E + + E E +L +K ++E+ E ++ID+L
Sbjct: 916 KTKIQLEAKIKEVTERAEDE-EEINAELTAKKRKLEDE---CSELKKDIDDLELTLAKVE 971
Query: 483 KSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLR 542
K K +TE +K++ + + E + N +T+ +
Sbjct: 972 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAE-EDKVNTLTKAK 1030
Query: 543 EFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKK 602
++D+ + Q++ +L + + + + L+ + I + + + L KK
Sbjct: 1031 -IKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKK 1089
Query: 603 EKEIKMLNEKEEEHMNIINLLHNKLE 628
E EI L K E+ + L K++
Sbjct: 1090 EFEISNLQSKIEDEQALGIQLQKKIK 1115
Score = 41.9 bits (94), Expect = 0.007
Identities = 31/108 (28%), Positives = 56/108 (51%), Gaps = 15/108 (13%)
Query: 391 KLIEIEKKYNDSIEEKKTLQ---ENIDDLRTDLLESELRVKDLVRELDEKESILETKQC- 446
+L +I+ Y +S+++ +TL+ +N+ +DL E + EL++ + +E ++C
Sbjct: 1486 ELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCE 1545
Query: 447 VQKELESTKTDLEHRKTEI-----------EEYKRLLFEKGEEIDELK 483
+Q LE + LEH + +I E R + EK EEID+LK
Sbjct: 1546 LQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLK 1593
Score = 41.1 bits (92), Expect = 0.013
Identities = 118/653 (18%), Positives = 243/653 (37%), Gaps = 67/653 (10%)
Query: 23 EQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKM-KLLGQ 81
E + I E K + +EKMVT K K +L Q QV L + + +L+
Sbjct: 861 EFQKIKDELAKSEAKRKELEEKMVTLLKEKNDL---QLQVQAEAEGLADAEERCDQLIKT 917
Query: 82 KVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVD 141
K+ L E I V + +A + ++ ++T K L D
Sbjct: 918 KIQL----EAKIKEVTE---------------RAEDEEEINAELTAKKRK-------LED 951
Query: 142 KCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEI 201
+C E +K+I + +L EK K+K E + LD+ + KE
Sbjct: 952 ECSEL---KKDIDDLELTLAKVEK--EKHATENKVKNLTEE----MAGLDETIAKLTKEK 1002
Query: 202 NDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXX 261
+ + ++ ++ A + + L+ A L Q ++ + R R
Sbjct: 1003 KALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLE 1062
Query: 262 XXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXX 321
I ++ + + +LK + L++ +E ++ L++ +
Sbjct: 1063 GDLKLAQESIMDIENEK-QQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARI 1121
Query: 322 XXXXEDFDQELNKLTQSIK---DNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSI 378
E+ + E ++ K D + LE+I+ E+ A + K
Sbjct: 1122 EELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMR 1181
Query: 379 KDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKE 438
+D++ + A + KK+ DS+ E L E ID+L+ + E ++ E+D+
Sbjct: 1182 RDLEEATLQHEATAATLRKKHADSVAE---LGEQIDNLQRVKQKLEKEKSEMKMEIDDLA 1238
Query: 439 SILETKQCVQKELESTKTDLEHRKTEI----EEYKRLLFEKGEEIDELKSKLSTEKAIKD 494
S +ET + LE LE + +E+ EE +RL+ ++ + +L TE
Sbjct: 1239 SNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLI----NDLTAQRGRLQTESG--- 1291
Query: 495 IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVG 554
+ ++K EE + KN + + D + +
Sbjct: 1292 EFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHD-CDLLR 1350
Query: 555 NMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEE 614
++++ EL + + + ++ + + TE+ L + +K++ + E
Sbjct: 1351 EQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEE---LEEAKKKLAQRLQAAE 1407
Query: 615 EHMNIIN-----LLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVL 662
EH+ +N L K L+NE + D+++ + + + + +K +++L
Sbjct: 1408 EHVEAVNAKCASLEKTKQRLQNEVE-DLMLDVERTNAACAALDKKQRNFDKIL 1459
Score = 38.7 bits (86), Expect = 0.070
Identities = 103/589 (17%), Positives = 218/589 (37%), Gaps = 33/589 (5%)
Query: 37 LKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKV--NLPSAEE-LHI 93
L V +EK T E K L + + E A L + ++ Q+ +L + E+ ++
Sbjct: 967 LAKVEKEKHAT-ENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNT 1025
Query: 94 MNVAKLSPEQLLQLCAGG---EPKA---LEHST--LDNKVTFDVNKLLNIPNSLVDKCEE 145
+ AK+ EQ + G E K LE + L+ + +++I N + +E
Sbjct: 1026 LTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEK-QQLDE 1084
Query: 146 TLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDII 205
L K++ I+ +S + E+ + + L KIKE A + L+ ++ R K
Sbjct: 1085 KLKKKEFEISNLQSKIEDEQALGIQ-LQKKIKELQARIEELEEEIEAERASRAKAEKQRS 1143
Query: 206 DCLRKNANETMALQLRTKELSCALSDLNTQNAE---MRKQIHSG--DHHRPYAN-RNXXX 259
D R+ + L+ S + + AE MR+ + H A R
Sbjct: 1144 DLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHA 1203
Query: 260 XXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXX 319
+K +L + + ++K ++ + + +A+ + RT+
Sbjct: 1204 DSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLS 1263
Query: 320 XXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIK 379
E+ + +N LT T + + ++ ++ ++ + I+
Sbjct: 1264 ELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRG----KQAFTQQIE 1319
Query: 380 DMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKES 439
++K ++ I + S + L+E ++ + E + + E+ + +
Sbjct: 1320 ELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRT 1379
Query: 440 ILETKQCVQ-KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXX 498
ET + +ELE K L R EE+ + K +++ K +L E ++D+
Sbjct: 1380 KYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNE--VEDLMLD 1437
Query: 499 XXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMIN 558
+ E L+ + R G L + N
Sbjct: 1438 VERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGT--ELFKIKNAYE 1495
Query: 559 QQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK 607
+ D+L E KR+ ++ LQ + +++ + ++ H L K +K+++
Sbjct: 1496 ESLDQL-ETLKRE---NKNLQQEISDLTEQIAEGGKRIHELEKIKKQVE 1540
Score = 32.7 bits (71), Expect = 4.6
Identities = 23/95 (24%), Positives = 47/95 (49%), Gaps = 4/95 (4%)
Query: 400 NDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLE 459
ND+I KK ++ +++++ L + + +R + IL+ Q + ++ DL+
Sbjct: 1615 NDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLK 1674
Query: 460 HRKTEIEEYKRLLFEKGEEIDELKSKL-STEKAIK 493
+ +E LL EI+EL++ L TE++ K
Sbjct: 1675 EQLAMVERRANLL---QAEIEELRATLEQTERSRK 1706
>AF111784-1|AAD29950.1| 1941|Homo sapiens myosin heavy chain IIa
protein.
Length = 1941
Score = 57.2 bits (132), Expect = 2e-07
Identities = 80/462 (17%), Positives = 181/462 (39%), Gaps = 24/462 (5%)
Query: 164 EKGIST-KTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRT 222
EK ++T K KIK+ A+++ + L++ LKE ND+ ++ A + R
Sbjct: 852 EKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERC 911
Query: 223 KELSCALSDLNTQNAEMRKQIHSGDHHRPY--ANRNXXXXXXXXXXXXXXXXSIMKDRLS 280
+L L + E+ ++ + A + + ++
Sbjct: 912 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 971
Query: 281 RAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQS-- 338
+ +H + V+ + + A L++ ++ ++ + + + ++N LT++
Sbjct: 972 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKI 1031
Query: 339 -IKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEK 397
++ LE +KL+ +SI D+++E ++++
Sbjct: 1032 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ-------QLDE 1084
Query: 398 KYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTD 457
K E LQ I+D + ++ + ++K+L ++E E +E ++ + + E ++D
Sbjct: 1085 KLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSD 1144
Query: 458 LEHRKTEIEEYKRLLFEKGEEID---ELKSKLSTE--KAIKDIXXXXXXXXXXXXXXXXX 512
L E+EE L E G E+ K E K +D+
Sbjct: 1145 LSR---ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKK 1201
Query: 513 XXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQE 572
Q+ + L+ + ++++ D+L +++ + L ++ + E
Sbjct: 1202 HADSVAELGEQIDNLQRVKQKLEKEKSEMKM--EIDDLASNVETVSKAKGNLEKMCRTLE 1259
Query: 573 EYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEI-KMLNEKE 613
+ +L++KE E +RL+ +T Q L + E + L+EKE
Sbjct: 1260 DQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKE 1301
Score = 48.8 bits (111), Expect = 7e-05
Identities = 70/368 (19%), Positives = 154/368 (41%), Gaps = 25/368 (6%)
Query: 277 DRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLT 336
D+L + + QL+ ++ V + E+ +E + +R + +D + L K+
Sbjct: 912 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 971
Query: 337 QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHE---MNLNIAKLI 393
+ ++++ L ++ +++ D++ E +N I
Sbjct: 972 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKI 1031
Query: 394 EIEKKYND---SIEEKKTLQENID----DLRTDLLESELRVKDLVRELDEKESILETKQC 446
++E++ +D S+E++K L+ +++ L DL ++ + D+ E + + L+ K+
Sbjct: 1032 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEF 1091
Query: 447 VQKELESTKTDLE----HRKTEIEEYKRLLFEKGEEID-ELKSKLSTEKAIKDIXXXXXX 501
L+S D + + +I+E + + E EEI+ E S+ EK D+
Sbjct: 1092 EISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEE 1151
Query: 502 XXXXXXXXXXXXXXXXXX---RESQMKSYYEEL--MNLKNQITQ--LREFGAFDNLNDVG 554
RE++ + +L L+++ T LR+ A D++ ++G
Sbjct: 1152 ISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHA-DSVAELG 1210
Query: 555 NMI-NQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKE 613
I N QR K +L K + E ++ + ++ + ++ E + E ++ L KE
Sbjct: 1211 EQIDNLQRVKQ-KLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKE 1269
Query: 614 EEHMNIIN 621
EE +IN
Sbjct: 1270 EEQQRLIN 1277
Score = 45.6 bits (103), Expect = 6e-04
Identities = 51/266 (19%), Positives = 109/266 (40%), Gaps = 15/266 (5%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLV 431
A+ + + +K E+ + AK E+E+K ++EK LQ + L ++E R L+
Sbjct: 856 ATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLI 915
Query: 432 R-ELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDEL-------- 482
+ ++ + I E + + E E +L +K ++E+ E ++ID+L
Sbjct: 916 KTKIQLEAKIKEVTERAEDE-EEINAELTAKKRKLEDE---CSELKKDIDDLELTLAKVE 971
Query: 483 KSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLR 542
K K +TE +K++ + + E + N +T+ +
Sbjct: 972 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAE-EDKVNTLTKAK 1030
Query: 543 EFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKK 602
++D+ + Q++ +L + + + + L+ + I + + + L KK
Sbjct: 1031 -IKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKK 1089
Query: 603 EKEIKMLNEKEEEHMNIINLLHNKLE 628
E EI L K E+ + L K++
Sbjct: 1090 EFEISNLQSKIEDEQALGIQLQKKIK 1115
Score = 41.9 bits (94), Expect = 0.007
Identities = 31/108 (28%), Positives = 56/108 (51%), Gaps = 15/108 (13%)
Query: 391 KLIEIEKKYNDSIEEKKTLQ---ENIDDLRTDLLESELRVKDLVRELDEKESILETKQC- 446
+L +I+ Y +S+++ +TL+ +N+ +DL E + EL++ + +E ++C
Sbjct: 1486 ELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCE 1545
Query: 447 VQKELESTKTDLEHRKTEI-----------EEYKRLLFEKGEEIDELK 483
+Q LE + LEH + +I E R + EK EEID+LK
Sbjct: 1546 LQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLK 1593
Score = 41.1 bits (92), Expect = 0.013
Identities = 118/653 (18%), Positives = 243/653 (37%), Gaps = 67/653 (10%)
Query: 23 EQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKM-KLLGQ 81
E + I E K + +EKMVT K K +L Q QV L + + +L+
Sbjct: 861 EFQKIKDELAKSEAKRKELEEKMVTLLKEKNDL---QLQVQAEAEGLADAEERCDQLIKT 917
Query: 82 KVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVD 141
K+ L E I V + +A + ++ ++T K L D
Sbjct: 918 KIQL----EAKIKEVTE---------------RAEDEEEINAELTAKKRK-------LED 951
Query: 142 KCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEI 201
+C E +K+I + +L EK K+K E + LD+ + KE
Sbjct: 952 ECSEL---KKDIDDLELTLAKVEK--EKHATENKVKNLTEE----MAGLDETIAKLTKEK 1002
Query: 202 NDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXX 261
+ + ++ ++ A + + L+ A L Q ++ + R R
Sbjct: 1003 KALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLE 1062
Query: 262 XXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXX 321
I ++ + + +LK + L++ +E ++ L++ +
Sbjct: 1063 GDLKLAQESIMDIENEK-QQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARI 1121
Query: 322 XXXXEDFDQELNKLTQSIK---DNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSI 378
E+ + E ++ K D + LE+I+ E+ A + K
Sbjct: 1122 EELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMR 1181
Query: 379 KDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKE 438
+D++ + A + KK+ DS+ E L E ID+L+ + E ++ E+D+
Sbjct: 1182 RDLEEATLQHEATAATLRKKHADSVAE---LGEQIDNLQRVKQKLEKEKSEMKMEIDDLA 1238
Query: 439 SILETKQCVQKELESTKTDLEHRKTEI----EEYKRLLFEKGEEIDELKSKLSTEKAIKD 494
S +ET + LE LE + +E+ EE +RL+ ++ + +L TE
Sbjct: 1239 SNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLI----NDLTAQRGRLQTESG--- 1291
Query: 495 IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVG 554
+ ++K EE + KN + + D + +
Sbjct: 1292 EFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHD-CDLLR 1350
Query: 555 NMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEE 614
++++ EL + + + ++ + + TE+ L + +K++ + E
Sbjct: 1351 EQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEE---LEEAKKKLAQRLQAAE 1407
Query: 615 EHMNIIN-----LLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVL 662
EH+ +N L K L+NE + D+++ + + + + +K +++L
Sbjct: 1408 EHVEAVNAKCASLEKTKQRLQNEVE-DLMLDVERTNAACAALDKKQRNFDKIL 1459
Score = 38.7 bits (86), Expect = 0.070
Identities = 103/589 (17%), Positives = 218/589 (37%), Gaps = 33/589 (5%)
Query: 37 LKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKV--NLPSAEE-LHI 93
L V +EK T E K L + + E A L + ++ Q+ +L + E+ ++
Sbjct: 967 LAKVEKEKHAT-ENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNT 1025
Query: 94 MNVAKLSPEQLLQLCAGG---EPKA---LEHST--LDNKVTFDVNKLLNIPNSLVDKCEE 145
+ AK+ EQ + G E K LE + L+ + +++I N + +E
Sbjct: 1026 LTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEK-QQLDE 1084
Query: 146 TLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDII 205
L K++ I+ +S + E+ + + L KIKE A + L+ ++ R K
Sbjct: 1085 KLKKKEFEISNLQSKIEDEQALGIQ-LQKKIKELQARIEELEEEIEAERASRAKAEKQRS 1143
Query: 206 DCLRKNANETMALQLRTKELSCALSDLNTQNAE---MRKQIHSG--DHHRPYAN-RNXXX 259
D R+ + L+ S + + AE MR+ + H A R
Sbjct: 1144 DLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHA 1203
Query: 260 XXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXX 319
+K +L + + ++K ++ + + +A+ + RT+
Sbjct: 1204 DSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLS 1263
Query: 320 XXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIK 379
E+ + +N LT T + + ++ ++ ++ + I+
Sbjct: 1264 ELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRG----KQAFTQQIE 1319
Query: 380 DMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKES 439
++K ++ I + S + L+E ++ + E + + E+ + +
Sbjct: 1320 ELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRT 1379
Query: 440 ILETKQCVQ-KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXX 498
ET + +ELE K L R EE+ + K +++ K +L E ++D+
Sbjct: 1380 KYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNE--VEDLMLD 1437
Query: 499 XXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMIN 558
+ E L+ + R G L + N
Sbjct: 1438 VERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGT--ELFKIKNAYE 1495
Query: 559 QQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK 607
+ D+L E KR+ ++ LQ + +++ + ++ H L K +K+++
Sbjct: 1496 ESLDQL-ETLKRE---NKNLQQEISDLTEQIAEGGKRIHELEKIKKQVE 1540
Score = 32.7 bits (71), Expect = 4.6
Identities = 23/95 (24%), Positives = 47/95 (49%), Gaps = 4/95 (4%)
Query: 400 NDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLE 459
ND+I KK ++ +++++ L + + +R + IL+ Q + ++ DL+
Sbjct: 1615 NDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLK 1674
Query: 460 HRKTEIEEYKRLLFEKGEEIDELKSKL-STEKAIK 493
+ +E LL EI+EL++ L TE++ K
Sbjct: 1675 EQLAMVERRANLL---QAEIEELRATLEQTERSRK 1706
>AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion protein
protein.
Length = 1492
Score = 56.4 bits (130), Expect = 3e-07
Identities = 74/348 (21%), Positives = 150/348 (43%), Gaps = 24/348 (6%)
Query: 330 QELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEM--NL 387
Q+L + ++D ED + LQ + NK K + L
Sbjct: 275 QQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEEL 334
Query: 388 NIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD-----EKESILE 442
N K+IE EKK + ++ T + + +L+ +++ +K++ EL E++S E
Sbjct: 335 N-TKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEE 393
Query: 443 TKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXX 502
KQ + E K + + + E + +R+ E ++++L+++L + +
Sbjct: 394 IKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELI 453
Query: 503 XXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRD 562
E+ ++SY +N ++QI + A + LN N Q++
Sbjct: 454 RQHMAQMEEMKTRHKGEMENALRSYSNITVN-EDQIKLMNV--AINELNIKLQDTNSQKE 510
Query: 563 KLFE-----------LTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNE 611
KL E L ++ E+ E+L +I+R +++ EQE LN+ K + + +
Sbjct: 511 KLKEELGLILEEKCALQRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVED 570
Query: 612 KEEEHMNIINLLHNKLELRNEADI-DVIITLAKYKKSLTLVLEKMSIS 658
+ E ++ + +LEL++EA++ + I L +K VL++M+ S
Sbjct: 571 LKAEIVS-ASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAES 617
Score = 46.4 bits (105), Expect = 3e-04
Identities = 31/110 (28%), Positives = 59/110 (53%), Gaps = 9/110 (8%)
Query: 378 IKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDD--LRTDLLESELRVKDLVRELD 435
+ EM L I +L + + +EK TL++ + + L+T+LLE +++ K+ +L
Sbjct: 710 VNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKE--NDLQ 767
Query: 436 EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSK 485
EK + LE + + K+ + T D+ T + + +RL+F +D +KSK
Sbjct: 768 EKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIF-----LDSIKSK 812
Score = 45.2 bits (102), Expect = 8e-04
Identities = 49/235 (20%), Positives = 98/235 (41%), Gaps = 9/235 (3%)
Query: 434 LDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIK 493
L EK + E +Q + E S K +++ ++T IEE + E+ ++ ELK KL+T +
Sbjct: 301 LQEKIKVYEMEQDKKVE-NSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLL 359
Query: 494 DIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDV 553
+E Q ++LM ++ + + + V
Sbjct: 360 GELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIV 419
Query: 554 GNMINQQRDKLFELTKRQEE-YDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEK 612
M + + KL +L +E Y +++ + E+ R + E+ +K E E + +
Sbjct: 420 QRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYS 479
Query: 613 ----EEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVLK 663
E+ + ++N+ N+L ++ + D K K+ L L+LE+ R L+
Sbjct: 480 NITVNEDQIKLMNVAINELNIKLQ---DTNSQKEKLKEELGLILEEKCALQRQLE 531
Score = 41.9 bits (94), Expect = 0.007
Identities = 76/418 (18%), Positives = 181/418 (43%), Gaps = 38/418 (9%)
Query: 275 MKDRLSRAEHQLKTNVERVVQLEAALEQARSE---SWSLERTVXXXXXXXXXXXEDFDQE 331
+KD+L+ A+ L E++VQ ++ + E S ER E+ +
Sbjct: 348 LKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKR 407
Query: 332 LNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEM-NLNIA 390
+K +Q D +E + KL+ Y + I MK E+ ++A
Sbjct: 408 NHKDSQFETDIVQRMEQET--QRKLEQLRAEL-------DEMYGQQIVQMKQELIRQHMA 458
Query: 391 KLIEIEKKYNDSIEEKKTLQENI----DDLRT-DLLESELRVK--DLVRELDE-KES--- 439
++ E++ ++ +E NI D ++ ++ +EL +K D + ++ KE
Sbjct: 459 QMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGL 518
Query: 440 ILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIK-DIXXX 498
ILE K +Q++LE +L + +I+ ++ + E+ +++E LST + +K +I
Sbjct: 519 ILEEKCALQRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSA 578
Query: 499 XXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNL----KNQITQLREFGAFDNLNDVG 554
E K L + + ++ +LR F + ++
Sbjct: 579 SESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELS 638
Query: 555 NMINQ-QRDKLFELTKRQE----EYDEKLQTKENEIKRLVESMT-EQEHVLNKKEKEIKM 608
+ + + + K ++ Y +++ +NE+ + +E+M E+++++ K+ + I
Sbjct: 639 KLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILE 698
Query: 609 LNEKEEEHMNIINLLHNKLELR-NE--ADIDVIITLAKYKKSLTLVLEKMSISNRVLK 663
+++ ++ +++N ++ L+ NE +I+++ K K +L ++++ + +L+
Sbjct: 699 ISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLE 756
Score = 40.3 bits (90), Expect = 0.023
Identities = 51/306 (16%), Positives = 131/306 (42%), Gaps = 36/306 (11%)
Query: 329 DQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLN 388
+ ++ + +I + L+D +EKL+ + + ++D+ E++ +
Sbjct: 485 EDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEE----KCALQRQLEDLVEELSFS 540
Query: 389 ---IAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETK- 444
I + + + + E ++DL+ +++ + K+L + + + + + K
Sbjct: 541 REQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKL 600
Query: 445 QCVQKELESTKTDL-EHRKTEIEEYK-RLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXX 502
+ ++KE + + E ++ E+E + +LLF EE+ +LK L E I
Sbjct: 601 EMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRIN--------- 651
Query: 503 XXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRD 562
+++ Y +++ L+N+++Q E F+ N+I +Q
Sbjct: 652 -------------IEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEK----DNLITKQNQ 694
Query: 563 KLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINL 622
+ E++K ++ + +K E+ + + ++ +L ++EKE L ++ +E L
Sbjct: 695 LILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTEL 754
Query: 623 LHNKLE 628
L +++
Sbjct: 755 LEKQMK 760
Score = 37.9 bits (84), Expect = 0.12
Identities = 97/489 (19%), Positives = 195/489 (39%), Gaps = 53/489 (10%)
Query: 4 EELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVM 63
EEL + Q + + EQES +E+HK + ++V+ +S+KELE +
Sbjct: 535 EELSFSREQIQRAR-QTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELE------L 587
Query: 64 ELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDN 123
+ A + N K+++L ++ N + + A+L + L + E + L+
Sbjct: 588 KHEAEVTNYKIKLEMLEKEKN-AVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEI 646
Query: 124 KVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAEN 183
+ ++ KL + N + ++ + E+ E++ ++ + TK I E +
Sbjct: 647 EHRINIEKLKD--NLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQ-NQLILEISKLK 703
Query: 184 DLLKSSLDQLRTEFLKEINDI---IDCLRKNANETMALQLRTKELSCALSDLNTQNAEMR 240
DL +S ++ E +IN++ I+ LR+ E L+ +EL L T+ E +
Sbjct: 704 DLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQEL-----QLKTELLEKQ 758
Query: 241 KQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNV-----ERVVQ 295
+ D +A SI+KD E LK + ER++
Sbjct: 759 MKEKENDLQEKFAQ-------------LEAENSILKDEKKTLEDMLKIHTPVSQEERLIF 805
Query: 296 LEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKD--NTTHL--EDIAL 351
L++ +++ W E + ED Q+ +L + I+ NT ++ +
Sbjct: 806 LDSIKSKSKDSVWEKEIEI------LIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEV 859
Query: 352 AREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQE 411
++LQ S NK + K ++ + + + +++ +++ K ++ +
Sbjct: 860 NYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKA-LNEELHLQRINPTTVKMKSSVFD 918
Query: 412 NIDDLRTDLLE-SELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEI----E 466
+ LE E+ KD +++ E K + + L L+ + EI E
Sbjct: 919 EDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQLKQKHGEISFLNE 978
Query: 467 EYKRLLFEK 475
E K L EK
Sbjct: 979 EVKSLKQEK 987
Score = 35.9 bits (79), Expect = 0.49
Identities = 96/461 (20%), Positives = 176/461 (38%), Gaps = 37/461 (8%)
Query: 42 QEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSP 101
++ M E+ K + + Y+++ ++KL+ +N + + L N K
Sbjct: 454 RQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIK-LQDTNSQKEKL 512
Query: 102 EQLLQLCAGGEPKALEHSTLD--NKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFES 159
++ L L E AL+ D +++F ++ ++ ++ E L + + ++ E
Sbjct: 513 KEELGLILE-EKCALQRQLEDLVEELSFSREQIQRARQTIAEQ-ESKLNEAHKSLSTVED 570
Query: 160 LMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNAN---ETM 216
L ++ S +++K AE K L+ L KE N ++D + ++ E +
Sbjct: 571 LKAEIVSASESRKELELKH-EAEVTNYKIKLEMLE----KEKNAVLDRMAESQEAELERL 625
Query: 217 ALQL---RTKELSCALSDLNTQ---NAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXX 270
QL +ELS DL + N E K + G H++ +
Sbjct: 626 RTQLLFSHEEELSKLKEDLEIEHRINIEKLKD-NLGIHYKQQID-----GLQNEMSQKIE 679
Query: 271 XXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQ 330
KD L ++QL + ++ L+ +L ++SE +L+ E
Sbjct: 680 TMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKG 739
Query: 331 ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMK--HEMNLN 388
L + Q ++ T LE +E K+++DM H
Sbjct: 740 TLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQ 799
Query: 389 IAKLI---EIEKKYNDSIEEK--KTLQENIDDLRTDLLESELRVKDLVRELDEKESILET 443
+LI I+ K DS+ EK + L E +DL+ ++ ++ E E
Sbjct: 800 EERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEV 859
Query: 444 K-QCVQKE---LESTKTDLEHRKTEIE-EYKRLLFEKGEEI 479
Q +Q+E L K DLE K + E EYK L EE+
Sbjct: 860 NYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEEL 900
>AJ131693-1|CAB40713.1| 3908|Homo sapiens AKAP450 protein protein.
Length = 3908
Score = 56.4 bits (130), Expect = 3e-07
Identities = 74/348 (21%), Positives = 150/348 (43%), Gaps = 24/348 (6%)
Query: 330 QELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEM--NL 387
Q+L + ++D ED + LQ + NK K + L
Sbjct: 275 QQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEEL 334
Query: 388 NIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD-----EKESILE 442
N K+IE EKK + ++ T + + +L+ +++ +K++ EL E++S E
Sbjct: 335 N-TKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEE 393
Query: 443 TKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXX 502
KQ + E K + + + E + +R+ E ++++L+++L + +
Sbjct: 394 IKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELI 453
Query: 503 XXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRD 562
E+ ++SY +N ++QI + A + LN N Q++
Sbjct: 454 RQHMAQMEEMKTRHKGEMENALRSYSNITVN-EDQIKLMNV--AINELNIKLQDTNSQKE 510
Query: 563 KLFE-----------LTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNE 611
KL E L ++ E+ E+L +I+R +++ EQE LN+ K + + +
Sbjct: 511 KLKEELGLILEEKCALQRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVED 570
Query: 612 KEEEHMNIINLLHNKLELRNEADI-DVIITLAKYKKSLTLVLEKMSIS 658
+ E ++ + +LEL++EA++ + I L +K VL++M+ S
Sbjct: 571 LKAEIVS-ASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAES 617
Score = 46.4 bits (105), Expect = 3e-04
Identities = 31/110 (28%), Positives = 59/110 (53%), Gaps = 9/110 (8%)
Query: 378 IKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDD--LRTDLLESELRVKDLVRELD 435
+ EM L I +L + + +EK TL++ + + L+T+LLE +++ K+ +L
Sbjct: 710 VNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKE--NDLQ 767
Query: 436 EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSK 485
EK + LE + + K+ + T D+ T + + +RL+F +D +KSK
Sbjct: 768 EKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIF-----LDSIKSK 812
Score = 45.2 bits (102), Expect = 8e-04
Identities = 49/235 (20%), Positives = 98/235 (41%), Gaps = 9/235 (3%)
Query: 434 LDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIK 493
L EK + E +Q + E S K +++ ++T IEE + E+ ++ ELK KL+T +
Sbjct: 301 LQEKIKVYEMEQDKKVE-NSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLL 359
Query: 494 DIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDV 553
+E Q ++LM ++ + + + V
Sbjct: 360 GELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIV 419
Query: 554 GNMINQQRDKLFELTKRQEE-YDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEK 612
M + + KL +L +E Y +++ + E+ R + E+ +K E E + +
Sbjct: 420 QRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYS 479
Query: 613 ----EEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVLK 663
E+ + ++N+ N+L ++ + D K K+ L L+LE+ R L+
Sbjct: 480 NITVNEDQIKLMNVAINELNIKLQ---DTNSQKEKLKEELGLILEEKCALQRQLE 531
Score = 42.7 bits (96), Expect = 0.004
Identities = 67/290 (23%), Positives = 127/290 (43%), Gaps = 26/290 (8%)
Query: 394 EIEKKYNDSIEEKKTLQENIDDLRTDLLESE---LRVKDLVR--ELDEKESI-LETK-QC 446
++++ + EE + L+ + +L LL S +V+D ++ K + LE + Q
Sbjct: 2135 QLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPELSLEVQLQA 2194
Query: 447 VQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXX 506
+ ++ + ++ + + ++E+++ L K EE+ +L +L +K +
Sbjct: 2195 ERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKK-ESTTRLQELEQENK 2253
Query: 507 XXXXXXXXXXXXXRESQMKSYYEE--LMNLKNQITQLREFGAFDNLNDVGNMINQQRDKL 564
+ES S ++ L QI Q +E D LN+ + QQ K+
Sbjct: 2254 LFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEV-EIDQLNEQVTKLQQQL-KI 2311
Query: 565 FELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEK-EEEHMNIINL- 622
K EE +E ++ E +I+ L M++QE V +E+EI+ LNE E+ + N+
Sbjct: 2312 TTDNKVIEEKNELIRDLETQIECL---MSDQECVKRNREEEIEQLNEVIEKLQQELANIG 2368
Query: 623 ---LHNKLELRNEAD-----IDVIIT-LAKYKKSLTLVLEKMSISNRVLK 663
N L EAD +DV+I ++ + E+M+ VLK
Sbjct: 2369 QKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLK 2418
Score = 41.9 bits (94), Expect = 0.007
Identities = 76/418 (18%), Positives = 181/418 (43%), Gaps = 38/418 (9%)
Query: 275 MKDRLSRAEHQLKTNVERVVQLEAALEQARSE---SWSLERTVXXXXXXXXXXXEDFDQE 331
+KD+L+ A+ L E++VQ ++ + E S ER E+ +
Sbjct: 348 LKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKR 407
Query: 332 LNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEM-NLNIA 390
+K +Q D +E + KL+ Y + I MK E+ ++A
Sbjct: 408 NHKDSQFETDIVQRMEQET--QRKLEQLRAEL-------DEMYGQQIVQMKQELIRQHMA 458
Query: 391 KLIEIEKKYNDSIEEKKTLQENI----DDLRT-DLLESELRVK--DLVRELDE-KES--- 439
++ E++ ++ +E NI D ++ ++ +EL +K D + ++ KE
Sbjct: 459 QMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGL 518
Query: 440 ILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIK-DIXXX 498
ILE K +Q++LE +L + +I+ ++ + E+ +++E LST + +K +I
Sbjct: 519 ILEEKCALQRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSA 578
Query: 499 XXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNL----KNQITQLREFGAFDNLNDVG 554
E K L + + ++ +LR F + ++
Sbjct: 579 SESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELS 638
Query: 555 NMINQ-QRDKLFELTKRQE----EYDEKLQTKENEIKRLVESMT-EQEHVLNKKEKEIKM 608
+ + + + K ++ Y +++ +NE+ + +E+M E+++++ K+ + I
Sbjct: 639 KLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILE 698
Query: 609 LNEKEEEHMNIINLLHNKLELR-NE--ADIDVIITLAKYKKSLTLVLEKMSISNRVLK 663
+++ ++ +++N ++ L+ NE +I+++ K K +L ++++ + +L+
Sbjct: 699 ISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLE 756
Score = 41.1 bits (92), Expect = 0.013
Identities = 67/366 (18%), Positives = 146/366 (39%), Gaps = 33/366 (9%)
Query: 277 DRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLT 336
D + R E +L R+ +LEA +Q + E L R + QE KL
Sbjct: 1944 DIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLM 2003
Query: 337 QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIE 396
+ + E + R+ LQ K +K ++ ++ +++ IE+E
Sbjct: 2004 KEKLEVQCQAEKV---RDDLQ------------------KQVKALEIDVEEQVSRFIELE 2042
Query: 397 KKYNDSI----EEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELE 452
++ N + ++ + L++ ++ +R L E + D E D + ++ + K +
Sbjct: 2043 QEKNTELMDLRQQNQALEKQLEKMRKFLDEQAI---DREHERDVFQQEIQKLEQQLKVVP 2099
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXX 512
+ EH+ E+E+ L EK ++ EL LS E+ +DI
Sbjct: 2100 RFQPISEHQTREVEQLANHLKEKTDKCSEL--LLSKEQLQRDIQERNEEIEKLEFRVREL 2157
Query: 513 XXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQE 572
++ K E+ + + E L + I+++ ++ L ++ E
Sbjct: 2158 EQALLVSADTFQK--VEDRKHF-GAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLE 2214
Query: 573 EYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNE 632
++ E+L+ K E+++L + Q+ + +E++ N+ ++ M + L + + +
Sbjct: 2215 QFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMST 2274
Query: 633 ADIDVI 638
D V+
Sbjct: 2275 QDQHVL 2280
Score = 40.3 bits (90), Expect = 0.023
Identities = 51/306 (16%), Positives = 131/306 (42%), Gaps = 36/306 (11%)
Query: 329 DQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLN 388
+ ++ + +I + L+D +EKL+ + + ++D+ E++ +
Sbjct: 485 EDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEE----KCALQRQLEDLVEELSFS 540
Query: 389 ---IAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETK- 444
I + + + + E ++DL+ +++ + K+L + + + + + K
Sbjct: 541 REQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKL 600
Query: 445 QCVQKELESTKTDL-EHRKTEIEEYK-RLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXX 502
+ ++KE + + E ++ E+E + +LLF EE+ +LK L E I
Sbjct: 601 EMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRIN--------- 651
Query: 503 XXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRD 562
+++ Y +++ L+N+++Q E F+ N+I +Q
Sbjct: 652 -------------IEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEK----DNLITKQNQ 694
Query: 563 KLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINL 622
+ E++K ++ + +K E+ + + ++ +L ++EKE L ++ +E L
Sbjct: 695 LILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTEL 754
Query: 623 LHNKLE 628
L +++
Sbjct: 755 LEKQMK 760
Score = 36.7 bits (81), Expect = 0.28
Identities = 97/489 (19%), Positives = 195/489 (39%), Gaps = 53/489 (10%)
Query: 4 EELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVM 63
EEL + Q + + EQES +E+HK + ++V+ +S+KELE +
Sbjct: 535 EELSFSREQIQRAR-QTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELE------L 587
Query: 64 ELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDN 123
+ A + N K+++L ++ N + + A+L + L + E + L+
Sbjct: 588 KHEAEVTNYKIKLEMLEKEKN-AVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEI 646
Query: 124 KVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAEN 183
+ ++ KL + N + ++ + E+ E++ ++ + TK I E +
Sbjct: 647 EHRINIEKLKD--NLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQ-NQLILEISKLK 703
Query: 184 DLLKSSLDQLRTEFLKEINDI---IDCLRKNANETMALQLRTKELSCALSDLNTQNAEMR 240
DL +S ++ E +IN++ I+ LR+ E L+ +EL L T+ E +
Sbjct: 704 DLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQEL-----QLKTELLEKQ 758
Query: 241 KQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNV-----ERVVQ 295
+ D +A SI+KD E LK + ER++
Sbjct: 759 MKEKENDLQEKFAQ-------------LEAENSILKDEKKTLEDMLKIHTPVSQEERLIF 805
Query: 296 LEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKD--NTTHL--EDIAL 351
L++ +++ W E + ED Q+ +L + I+ NT ++ +
Sbjct: 806 LDSIKSKSKDSVWEKEIEI------LIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEV 859
Query: 352 AREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQE 411
++LQ S NK + K ++ + + + +++ +++ K ++ +
Sbjct: 860 NYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKA-LNEELHLQRINPTTVKMKSSVFD 918
Query: 412 NIDDLRTDLLE-SELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEI----E 466
+ LE E+ KD +++ E K + + L L+ + EI E
Sbjct: 919 EDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQLKPKPGEISFLNE 978
Query: 467 EYKRLLFEK 475
E K L EK
Sbjct: 979 EVKSLKPEK 987
Score = 35.9 bits (79), Expect = 0.49
Identities = 96/461 (20%), Positives = 176/461 (38%), Gaps = 37/461 (8%)
Query: 42 QEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSP 101
++ M E+ K + + Y+++ ++KL+ +N + + L N K
Sbjct: 454 RQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIK-LQDTNSQKEKL 512
Query: 102 EQLLQLCAGGEPKALEHSTLD--NKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFES 159
++ L L E AL+ D +++F ++ ++ ++ E L + + ++ E
Sbjct: 513 KEELGLILE-EKCALQRQLEDLVEELSFSREQIQRARQTIAEQ-ESKLNEAHKSLSTVED 570
Query: 160 LMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNAN---ETM 216
L ++ S +++K AE K L+ L KE N ++D + ++ E +
Sbjct: 571 LKAEIVSASESRKELELKH-EAEVTNYKIKLEMLE----KEKNAVLDRMAESQEAELERL 625
Query: 217 ALQL---RTKELSCALSDLNTQ---NAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXX 270
QL +ELS DL + N E K + G H++ +
Sbjct: 626 RTQLLFSHEEELSKLKEDLEIEHRINIEKLKD-NLGIHYKQQID-----GLQNEMSQKIE 679
Query: 271 XXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQ 330
KD L ++QL + ++ L+ +L ++SE +L+ E
Sbjct: 680 TMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKG 739
Query: 331 ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMK--HEMNLN 388
L + Q ++ T LE +E K+++DM H
Sbjct: 740 TLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQ 799
Query: 389 IAKLI---EIEKKYNDSIEEK--KTLQENIDDLRTDLLESELRVKDLVRELDEKESILET 443
+LI I+ K DS+ EK + L E +DL+ ++ ++ E E
Sbjct: 800 EERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEV 859
Query: 444 K-QCVQKE---LESTKTDLEHRKTEIE-EYKRLLFEKGEEI 479
Q +Q+E L K DLE K + E EYK L EE+
Sbjct: 860 NYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEEL 900
Score = 33.1 bits (72), Expect = 3.5
Identities = 35/199 (17%), Positives = 81/199 (40%), Gaps = 14/199 (7%)
Query: 340 KDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKY 399
++ +E + EKLQ + S ++ +KH++++ IA+ + +E++
Sbjct: 2344 RNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQV 2403
Query: 400 NDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELE-STKTDL 458
++ E+ T +N+ L E+ ++ L +EL + E+ + +Q E S +
Sbjct: 2404 -ETANEEMTFMKNV------LKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVNVAI 2456
Query: 459 EHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXX 518
+H + E + +L E D LKS L + K
Sbjct: 2457 DHLSKDKPELEVVLTE-----DALKS-LENQTYFKSFEENGKGSIINLETRLLQLESTVS 2510
Query: 519 XRESQMKSYYEELMNLKNQ 537
++ ++ Y+++ +++ Q
Sbjct: 2511 AKDLELTQCYKQIKDMQEQ 2529
>AJ010770-1|CAA09361.1| 3911|Homo sapiens Hyperion protein protein.
Length = 3911
Score = 56.4 bits (130), Expect = 3e-07
Identities = 74/348 (21%), Positives = 150/348 (43%), Gaps = 24/348 (6%)
Query: 330 QELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEM--NL 387
Q+L + ++D ED + LQ + NK K + L
Sbjct: 287 QQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEEL 346
Query: 388 NIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD-----EKESILE 442
N K+IE EKK + ++ T + + +L+ +++ +K++ EL E++S E
Sbjct: 347 N-TKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEE 405
Query: 443 TKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXX 502
KQ + E K + + + E + +R+ E ++++L+++L + +
Sbjct: 406 IKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELI 465
Query: 503 XXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRD 562
E+ ++SY +N ++QI + A + LN N Q++
Sbjct: 466 RQHMAQMEEMKTRHKGEMENALRSYSNITVN-EDQIKLMNV--AINELNIKLQDTNSQKE 522
Query: 563 KLFE-----------LTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNE 611
KL E L ++ E+ E+L +I+R +++ EQE LN+ K + + +
Sbjct: 523 KLKEELGLILEEKCALQRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVED 582
Query: 612 KEEEHMNIINLLHNKLELRNEADI-DVIITLAKYKKSLTLVLEKMSIS 658
+ E ++ + +LEL++EA++ + I L +K VL++M+ S
Sbjct: 583 LKAEIVS-ASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAES 629
Score = 46.4 bits (105), Expect = 3e-04
Identities = 31/110 (28%), Positives = 59/110 (53%), Gaps = 9/110 (8%)
Query: 378 IKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDD--LRTDLLESELRVKDLVRELD 435
+ EM L I +L + + +EK TL++ + + L+T+LLE +++ K+ +L
Sbjct: 722 VNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKE--NDLQ 779
Query: 436 EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSK 485
EK + LE + + K+ + T D+ T + + +RL+F +D +KSK
Sbjct: 780 EKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIF-----LDSIKSK 824
Score = 45.2 bits (102), Expect = 8e-04
Identities = 49/235 (20%), Positives = 98/235 (41%), Gaps = 9/235 (3%)
Query: 434 LDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIK 493
L EK + E +Q + E S K +++ ++T IEE + E+ ++ ELK KL+T +
Sbjct: 313 LQEKIKVYEMEQDKKVE-NSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLL 371
Query: 494 DIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDV 553
+E Q ++LM ++ + + + V
Sbjct: 372 GELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIV 431
Query: 554 GNMINQQRDKLFELTKRQEE-YDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEK 612
M + + KL +L +E Y +++ + E+ R + E+ +K E E + +
Sbjct: 432 QRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYS 491
Query: 613 ----EEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVLK 663
E+ + ++N+ N+L ++ + D K K+ L L+LE+ R L+
Sbjct: 492 NITVNEDQIKLMNVAINELNIKLQ---DTNSQKEKLKEELGLILEEKCALQRQLE 543
Score = 42.7 bits (96), Expect = 0.004
Identities = 67/290 (23%), Positives = 127/290 (43%), Gaps = 26/290 (8%)
Query: 394 EIEKKYNDSIEEKKTLQENIDDLRTDLLESE---LRVKDLVR--ELDEKESI-LETK-QC 446
++++ + EE + L+ + +L LL S +V+D ++ K + LE + Q
Sbjct: 2146 QLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPELSLEVQLQA 2205
Query: 447 VQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXX 506
+ ++ + ++ + + ++E+++ L K EE+ +L +L +K +
Sbjct: 2206 ERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKK-ESTTRLQELEQENK 2264
Query: 507 XXXXXXXXXXXXXRESQMKSYYEE--LMNLKNQITQLREFGAFDNLNDVGNMINQQRDKL 564
+ES S ++ L QI Q +E D LN+ + QQ K+
Sbjct: 2265 LFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEV-EIDQLNEQVTKLQQQL-KI 2322
Query: 565 FELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEK-EEEHMNIINL- 622
K EE +E ++ E +I+ L M++QE V +E+EI+ LNE E+ + N+
Sbjct: 2323 TTDNKVIEEKNELIRDLETQIECL---MSDQECVKRNREEEIEQLNEVIEKLQQELANIG 2379
Query: 623 ---LHNKLELRNEAD-----IDVIIT-LAKYKKSLTLVLEKMSISNRVLK 663
N L EAD +DV+I ++ + E+M+ VLK
Sbjct: 2380 QKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLK 2429
Score = 41.9 bits (94), Expect = 0.007
Identities = 76/418 (18%), Positives = 181/418 (43%), Gaps = 38/418 (9%)
Query: 275 MKDRLSRAEHQLKTNVERVVQLEAALEQARSE---SWSLERTVXXXXXXXXXXXEDFDQE 331
+KD+L+ A+ L E++VQ ++ + E S ER E+ +
Sbjct: 360 LKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKR 419
Query: 332 LNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEM-NLNIA 390
+K +Q D +E + KL+ Y + I MK E+ ++A
Sbjct: 420 NHKDSQFETDIVQRMEQET--QRKLEQLRAEL-------DEMYGQQIVQMKQELIRQHMA 470
Query: 391 KLIEIEKKYNDSIEEKKTLQENI----DDLRT-DLLESELRVK--DLVRELDE-KES--- 439
++ E++ ++ +E NI D ++ ++ +EL +K D + ++ KE
Sbjct: 471 QMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGL 530
Query: 440 ILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIK-DIXXX 498
ILE K +Q++LE +L + +I+ ++ + E+ +++E LST + +K +I
Sbjct: 531 ILEEKCALQRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSA 590
Query: 499 XXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNL----KNQITQLREFGAFDNLNDVG 554
E K L + + ++ +LR F + ++
Sbjct: 591 SESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELS 650
Query: 555 NMINQ-QRDKLFELTKRQE----EYDEKLQTKENEIKRLVESMT-EQEHVLNKKEKEIKM 608
+ + + + K ++ Y +++ +NE+ + +E+M E+++++ K+ + I
Sbjct: 651 KLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILE 710
Query: 609 LNEKEEEHMNIINLLHNKLELR-NE--ADIDVIITLAKYKKSLTLVLEKMSISNRVLK 663
+++ ++ +++N ++ L+ NE +I+++ K K +L ++++ + +L+
Sbjct: 711 ISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLE 768
Score = 41.1 bits (92), Expect = 0.013
Identities = 67/366 (18%), Positives = 146/366 (39%), Gaps = 33/366 (9%)
Query: 277 DRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLT 336
D + R E +L R+ +LEA +Q + E L R + QE KL
Sbjct: 1955 DIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLM 2014
Query: 337 QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIE 396
+ + E + R+ LQ K +K ++ ++ +++ IE+E
Sbjct: 2015 KEKLEVQCQAEKV---RDDLQ------------------KQVKALEIDVEEQVSRFIELE 2053
Query: 397 KKYNDSI----EEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELE 452
++ N + ++ + L++ ++ +R L E + D E D + ++ + K +
Sbjct: 2054 QEKNTELMDLRQQNQALEKQLEKMRKFLDEQAI---DREHERDVFQQEIQKLEQQLKVVP 2110
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXX 512
+ EH+ E+E+ L EK ++ EL LS E+ +DI
Sbjct: 2111 RFQPISEHQTREVEQLANHLKEKTDKCSEL--LLSKEQLQRDIQERNEEIEKLEFRVREL 2168
Query: 513 XXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQE 572
++ K E+ + + E L + I+++ ++ L ++ E
Sbjct: 2169 EQALLVSADTFQK--VEDRKHF-GAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLE 2225
Query: 573 EYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNE 632
++ E+L+ K E+++L + Q+ + +E++ N+ ++ M + L + + +
Sbjct: 2226 QFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMST 2285
Query: 633 ADIDVI 638
D V+
Sbjct: 2286 QDQHVL 2291
Score = 40.3 bits (90), Expect = 0.023
Identities = 51/306 (16%), Positives = 131/306 (42%), Gaps = 36/306 (11%)
Query: 329 DQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLN 388
+ ++ + +I + L+D +EKL+ + + ++D+ E++ +
Sbjct: 497 EDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEE----KCALQRQLEDLVEELSFS 552
Query: 389 ---IAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETK- 444
I + + + + E ++DL+ +++ + K+L + + + + + K
Sbjct: 553 REQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKL 612
Query: 445 QCVQKELESTKTDL-EHRKTEIEEYK-RLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXX 502
+ ++KE + + E ++ E+E + +LLF EE+ +LK L E I
Sbjct: 613 EMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRIN--------- 663
Query: 503 XXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRD 562
+++ Y +++ L+N+++Q E F+ N+I +Q
Sbjct: 664 -------------IEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEK----DNLITKQNQ 706
Query: 563 KLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINL 622
+ E++K ++ + +K E+ + + ++ +L ++EKE L ++ +E L
Sbjct: 707 LILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTEL 766
Query: 623 LHNKLE 628
L +++
Sbjct: 767 LEKQMK 772
Score = 38.3 bits (85), Expect = 0.092
Identities = 130/676 (19%), Positives = 274/676 (40%), Gaps = 77/676 (11%)
Query: 4 EELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVM 63
EEL + Q + + EQES +E+HK + ++V+ +S+KELE +
Sbjct: 547 EELSFSREQIQRAR-QTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELE------L 599
Query: 64 ELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDN 123
+ A + N K+++L ++ N + + A+L + L + E + L+
Sbjct: 600 KHEAEVTNYKIKLEMLEKEKN-AVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEI 658
Query: 124 KVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAEN 183
+ ++ KL + N + ++ + E+ E++ ++ + TK I E +
Sbjct: 659 EHRINIEKLKD--NLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQ-NQLILEISKLK 715
Query: 184 DLLKSSLDQLRTEFLKEINDI---IDCLRKNANETMALQLRTKELSCALSDLNTQNAEMR 240
DL +S ++ E +IN++ I+ LR+ E L+ +EL L T+ E +
Sbjct: 716 DLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQEL-----QLKTELLEKQ 770
Query: 241 KQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNV-----ERVVQ 295
+ D +A SI+KD E LK + ER++
Sbjct: 771 MKEKENDLQEKFAQ-------------LEAENSILKDEKKTLEDMLKIHTPVSQEERLIF 817
Query: 296 LEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKD--NTTHL--EDIAL 351
L++ +++ W E + ED Q+ +L + I+ NT ++ +
Sbjct: 818 LDSIKSKSKDSVWEKEIEI------LIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEV 871
Query: 352 AREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQE 411
++LQ S NK + K ++ + + + +++ +++ K ++
Sbjct: 872 NYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKA-LNEELHLQRINPTTVKMKSSV-- 928
Query: 412 NIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRL 471
D+ +T + E+ L + ++V E D E ++E + ++E K +L R +++ E
Sbjct: 929 -FDEDKTFVAET-LEMGEVV-EKDTTE-LMEKLEVTKRE----KLELSQRLSDLSEQ--- 977
Query: 472 LFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEEL 531
L +K EI L ++ + K K+ R ++S ++
Sbjct: 978 LKQKHGEISFLNEEVKSLKQEKE---------QVSLRCRELEIIINHNRAENVQSCDTQV 1028
Query: 532 MNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENE-IKRLVE 590
+L + + + GA +++ V ++ + E E ++K+ + I +
Sbjct: 1029 SSLLDGVVTMTSRGAEGSVSKVNKSFGEESKIMVEDKVSFENMTVGEESKQEQLILDHLP 1088
Query: 591 SMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTL 650
S+T++ + + E N+K ++ +N++ N L L+ EA + ++L Y +
Sbjct: 1089 SVTKESSLRATQPSE----NDKLQKELNVLKSEQNDLRLQMEAQ-RICLSLV-YSTHVDQ 1142
Query: 651 VLEKMSISNRVLKCSL 666
V E M CSL
Sbjct: 1143 VREYMENEKDKALCSL 1158
Score = 35.9 bits (79), Expect = 0.49
Identities = 96/461 (20%), Positives = 176/461 (38%), Gaps = 37/461 (8%)
Query: 42 QEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSP 101
++ M E+ K + + Y+++ ++KL+ +N + + L N K
Sbjct: 466 RQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIK-LQDTNSQKEKL 524
Query: 102 EQLLQLCAGGEPKALEHSTLD--NKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFES 159
++ L L E AL+ D +++F ++ ++ ++ E L + + ++ E
Sbjct: 525 KEELGLILE-EKCALQRQLEDLVEELSFSREQIQRARQTIAEQ-ESKLNEAHKSLSTVED 582
Query: 160 LMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNAN---ETM 216
L ++ S +++K AE K L+ L KE N ++D + ++ E +
Sbjct: 583 LKAEIVSASESRKELELKH-EAEVTNYKIKLEMLE----KEKNAVLDRMAESQEAELERL 637
Query: 217 ALQL---RTKELSCALSDLNTQ---NAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXX 270
QL +ELS DL + N E K + G H++ +
Sbjct: 638 RTQLLFSHEEELSKLKEDLEIEHRINIEKLKD-NLGIHYKQQID-----GLQNEMSQKIE 691
Query: 271 XXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQ 330
KD L ++QL + ++ L+ +L ++SE +L+ E
Sbjct: 692 TMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKG 751
Query: 331 ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMK--HEMNLN 388
L + Q ++ T LE +E K+++DM H
Sbjct: 752 TLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQ 811
Query: 389 IAKLI---EIEKKYNDSIEEK--KTLQENIDDLRTDLLESELRVKDLVRELDEKESILET 443
+LI I+ K DS+ EK + L E +DL+ ++ ++ E E
Sbjct: 812 EERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEV 871
Query: 444 K-QCVQKE---LESTKTDLEHRKTEIE-EYKRLLFEKGEEI 479
Q +Q+E L K DLE K + E EYK L EE+
Sbjct: 872 NYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEEL 912
Score = 33.1 bits (72), Expect = 3.5
Identities = 35/199 (17%), Positives = 81/199 (40%), Gaps = 14/199 (7%)
Query: 340 KDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKY 399
++ +E + EKLQ + S ++ +KH++++ IA+ + +E++
Sbjct: 2355 RNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQV 2414
Query: 400 NDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELE-STKTDL 458
++ E+ T +N+ L E+ ++ L +EL + E+ + +Q E S +
Sbjct: 2415 -ETANEEMTFMKNV------LKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVNVAI 2467
Query: 459 EHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXX 518
+H + E + +L E D LKS L + K
Sbjct: 2468 DHLSKDKPELEVVLTE-----DALKS-LENQTYFKSFEENGKGSIINLETRLLQLESTVS 2521
Query: 519 XRESQMKSYYEELMNLKNQ 537
++ ++ Y+++ +++ Q
Sbjct: 2522 AKDLELTQCYKQIKDMQEQ 2540
>AF026245-1|AAB86384.1| 1642|Homo sapiens yotiao protein.
Length = 1642
Score = 56.4 bits (130), Expect = 3e-07
Identities = 74/348 (21%), Positives = 150/348 (43%), Gaps = 24/348 (6%)
Query: 330 QELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEM--NL 387
Q+L + ++D ED + LQ + NK K + L
Sbjct: 287 QQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEEL 346
Query: 388 NIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD-----EKESILE 442
N K+IE EKK + ++ T + + +L+ +++ +K++ EL E++S E
Sbjct: 347 N-TKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEE 405
Query: 443 TKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXX 502
KQ + E K + + + E + +R+ E ++++L+++L + +
Sbjct: 406 IKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELI 465
Query: 503 XXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRD 562
E+ ++SY +N ++QI + A + LN N Q++
Sbjct: 466 RQHMAQMEEMKTRHKGEMENALRSYSNITVN-EDQIKLMNV--AINELNIKLQDTNSQKE 522
Query: 563 KLFE-----------LTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNE 611
KL E L ++ E+ E+L +I+R +++ EQE LN+ K + + +
Sbjct: 523 KLKEELGLILEEKCALQRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVED 582
Query: 612 KEEEHMNIINLLHNKLELRNEADI-DVIITLAKYKKSLTLVLEKMSIS 658
+ E ++ + +LEL++EA++ + I L +K VL++M+ S
Sbjct: 583 LKAEIVS-ASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAES 629
Score = 46.4 bits (105), Expect = 3e-04
Identities = 31/110 (28%), Positives = 59/110 (53%), Gaps = 9/110 (8%)
Query: 378 IKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDD--LRTDLLESELRVKDLVRELD 435
+ EM L I +L + + +EK TL++ + + L+T+LLE +++ K+ +L
Sbjct: 722 VNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKE--NDLQ 779
Query: 436 EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSK 485
EK + LE + + K+ + T D+ T + + +RL+F +D +KSK
Sbjct: 780 EKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIF-----LDSIKSK 824
Score = 45.2 bits (102), Expect = 8e-04
Identities = 49/235 (20%), Positives = 98/235 (41%), Gaps = 9/235 (3%)
Query: 434 LDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIK 493
L EK + E +Q + E S K +++ ++T IEE + E+ ++ ELK KL+T +
Sbjct: 313 LQEKIKVYEMEQDKKVE-NSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLL 371
Query: 494 DIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDV 553
+E Q ++LM ++ + + + V
Sbjct: 372 GELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIV 431
Query: 554 GNMINQQRDKLFELTKRQEE-YDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEK 612
M + + KL +L +E Y +++ + E+ R + E+ +K E E + +
Sbjct: 432 QRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYS 491
Query: 613 ----EEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVLK 663
E+ + ++N+ N+L ++ + D K K+ L L+LE+ R L+
Sbjct: 492 NITVNEDQIKLMNVAINELNIKLQ---DTNSQKEKLKEELGLILEEKCALQRQLE 543
Score = 41.9 bits (94), Expect = 0.007
Identities = 76/418 (18%), Positives = 181/418 (43%), Gaps = 38/418 (9%)
Query: 275 MKDRLSRAEHQLKTNVERVVQLEAALEQARSE---SWSLERTVXXXXXXXXXXXEDFDQE 331
+KD+L+ A+ L E++VQ ++ + E S ER E+ +
Sbjct: 360 LKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKR 419
Query: 332 LNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEM-NLNIA 390
+K +Q D +E + KL+ Y + I MK E+ ++A
Sbjct: 420 NHKDSQFETDIVQRMEQET--QRKLEQLRAEL-------DEMYGQQIVQMKQELIRQHMA 470
Query: 391 KLIEIEKKYNDSIEEKKTLQENI----DDLRT-DLLESELRVK--DLVRELDE-KES--- 439
++ E++ ++ +E NI D ++ ++ +EL +K D + ++ KE
Sbjct: 471 QMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGL 530
Query: 440 ILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIK-DIXXX 498
ILE K +Q++LE +L + +I+ ++ + E+ +++E LST + +K +I
Sbjct: 531 ILEEKCALQRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSA 590
Query: 499 XXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNL----KNQITQLREFGAFDNLNDVG 554
E K L + + ++ +LR F + ++
Sbjct: 591 SESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELS 650
Query: 555 NMINQ-QRDKLFELTKRQE----EYDEKLQTKENEIKRLVESMT-EQEHVLNKKEKEIKM 608
+ + + + K ++ Y +++ +NE+ + +E+M E+++++ K+ + I
Sbjct: 651 KLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILE 710
Query: 609 LNEKEEEHMNIINLLHNKLELR-NE--ADIDVIITLAKYKKSLTLVLEKMSISNRVLK 663
+++ ++ +++N ++ L+ NE +I+++ K K +L ++++ + +L+
Sbjct: 711 ISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLE 768
Score = 40.3 bits (90), Expect = 0.023
Identities = 51/306 (16%), Positives = 131/306 (42%), Gaps = 36/306 (11%)
Query: 329 DQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLN 388
+ ++ + +I + L+D +EKL+ + + ++D+ E++ +
Sbjct: 497 EDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEE----KCALQRQLEDLVEELSFS 552
Query: 389 ---IAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETK- 444
I + + + + E ++DL+ +++ + K+L + + + + + K
Sbjct: 553 REQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKL 612
Query: 445 QCVQKELESTKTDL-EHRKTEIEEYK-RLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXX 502
+ ++KE + + E ++ E+E + +LLF EE+ +LK L E I
Sbjct: 613 EMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRIN--------- 663
Query: 503 XXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRD 562
+++ Y +++ L+N+++Q E F+ N+I +Q
Sbjct: 664 -------------IEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEK----DNLITKQNQ 706
Query: 563 KLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINL 622
+ E++K ++ + +K E+ + + ++ +L ++EKE L ++ +E L
Sbjct: 707 LILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTEL 766
Query: 623 LHNKLE 628
L +++
Sbjct: 767 LEKQMK 772
Score = 37.5 bits (83), Expect = 0.16
Identities = 97/489 (19%), Positives = 195/489 (39%), Gaps = 53/489 (10%)
Query: 4 EELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVM 63
EEL + Q + + EQES +E+HK + ++V+ +S+KELE +
Sbjct: 547 EELSFSREQIQRAR-QTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELE------L 599
Query: 64 ELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDN 123
+ A + N K+++L ++ N + + A+L + L + E + L+
Sbjct: 600 KHEAEVTNYKIKLEMLEKEKN-AVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEI 658
Query: 124 KVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAEN 183
+ ++ KL + N + ++ + E+ E++ ++ + TK I E +
Sbjct: 659 EHRINIEKLKD--NLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQ-NQLILEISKLK 715
Query: 184 DLLKSSLDQLRTEFLKEINDI---IDCLRKNANETMALQLRTKELSCALSDLNTQNAEMR 240
DL +S ++ E +IN++ I+ LR+ E L+ +EL L T+ E +
Sbjct: 716 DLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQEL-----QLKTELLEKQ 770
Query: 241 KQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNV-----ERVVQ 295
+ D +A SI+KD E LK + ER++
Sbjct: 771 MKEKENDLQEKFAQ-------------LEAENSILKDEKKTLEDMLKIHTPVSQEERLIF 817
Query: 296 LEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKD--NTTHL--EDIAL 351
L++ +++ W E + ED Q+ +L + I+ NT ++ +
Sbjct: 818 LDSIKSKSKDSVWEKEIEI------LIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEV 871
Query: 352 AREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQE 411
++LQ S NK + K ++ + + + +++ +++ K ++ +
Sbjct: 872 NYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKA-LNEELHLQRINPTTVKMKSSVFD 930
Query: 412 NIDDLRTDLLE-SELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEI----E 466
+ LE E+ KD +++ E K + + L L+ + EI E
Sbjct: 931 EDKTFVAETLEMGEVXEKDTTELMEKLEVTKREKLELSQRLSDLSEQLKPKPGEISFLNE 990
Query: 467 EYKRLLFEK 475
E K L EK
Sbjct: 991 EVKSLKPEK 999
Score = 35.9 bits (79), Expect = 0.49
Identities = 96/461 (20%), Positives = 176/461 (38%), Gaps = 37/461 (8%)
Query: 42 QEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSP 101
++ M E+ K + + Y+++ ++KL+ +N + + L N K
Sbjct: 466 RQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIK-LQDTNSQKEKL 524
Query: 102 EQLLQLCAGGEPKALEHSTLD--NKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFES 159
++ L L E AL+ D +++F ++ ++ ++ E L + + ++ E
Sbjct: 525 KEELGLILE-EKCALQRQLEDLVEELSFSREQIQRARQTIAEQ-ESKLNEAHKSLSTVED 582
Query: 160 LMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNAN---ETM 216
L ++ S +++K AE K L+ L KE N ++D + ++ E +
Sbjct: 583 LKAEIVSASESRKELELKH-EAEVTNYKIKLEMLE----KEKNAVLDRMAESQEAELERL 637
Query: 217 ALQL---RTKELSCALSDLNTQ---NAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXX 270
QL +ELS DL + N E K + G H++ +
Sbjct: 638 RTQLLFSHEEELSKLKEDLEIEHRINIEKLKD-NLGIHYKQQID-----GLQNEMSQKIE 691
Query: 271 XXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQ 330
KD L ++QL + ++ L+ +L ++SE +L+ E
Sbjct: 692 TMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKG 751
Query: 331 ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMK--HEMNLN 388
L + Q ++ T LE +E K+++DM H
Sbjct: 752 TLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQ 811
Query: 389 IAKLI---EIEKKYNDSIEEK--KTLQENIDDLRTDLLESELRVKDLVRELDEKESILET 443
+LI I+ K DS+ EK + L E +DL+ ++ ++ E E
Sbjct: 812 EERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEV 871
Query: 444 K-QCVQKE---LESTKTDLEHRKTEIE-EYKRLLFEKGEEI 479
Q +Q+E L K DLE K + E EYK L EE+
Sbjct: 872 NYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEEL 912
>AC000066-1|AAC60380.1| 1620|Homo sapiens yotiao protein.
Length = 1620
Score = 56.4 bits (130), Expect = 3e-07
Identities = 74/348 (21%), Positives = 150/348 (43%), Gaps = 24/348 (6%)
Query: 330 QELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEM--NL 387
Q+L + ++D ED + LQ + NK K + L
Sbjct: 256 QQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEEL 315
Query: 388 NIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD-----EKESILE 442
N K+IE EKK + ++ T + + +L+ +++ +K++ EL E++S E
Sbjct: 316 N-TKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEE 374
Query: 443 TKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXX 502
KQ + E K + + + E + +R+ E ++++L+++L + +
Sbjct: 375 IKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELI 434
Query: 503 XXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRD 562
E+ ++SY +N ++QI + A + LN N Q++
Sbjct: 435 RQHMAQMEEMKTRHKGEMENALRSYSNITVN-EDQIKLMNV--AINELNIKLQDTNSQKE 491
Query: 563 KLFE-----------LTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNE 611
KL E L ++ E+ E+L +I+R +++ EQE LN+ K + + +
Sbjct: 492 KLKEELGLILEEKCALQRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVED 551
Query: 612 KEEEHMNIINLLHNKLELRNEADI-DVIITLAKYKKSLTLVLEKMSIS 658
+ E ++ + +LEL++EA++ + I L +K VL++M+ S
Sbjct: 552 LKAEIVS-ASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAES 598
Score = 46.4 bits (105), Expect = 3e-04
Identities = 31/110 (28%), Positives = 59/110 (53%), Gaps = 9/110 (8%)
Query: 378 IKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDD--LRTDLLESELRVKDLVRELD 435
+ EM L I +L + + +EK TL++ + + L+T+LLE +++ K+ +L
Sbjct: 691 VNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKE--NDLQ 748
Query: 436 EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSK 485
EK + LE + + K+ + T D+ T + + +RL+F +D +KSK
Sbjct: 749 EKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIF-----LDSIKSK 793
Score = 45.2 bits (102), Expect = 8e-04
Identities = 49/235 (20%), Positives = 98/235 (41%), Gaps = 9/235 (3%)
Query: 434 LDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIK 493
L EK + E +Q + E S K +++ ++T IEE + E+ ++ ELK KL+T +
Sbjct: 282 LQEKIKVYEMEQDKKVE-NSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLL 340
Query: 494 DIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDV 553
+E Q ++LM ++ + + + V
Sbjct: 341 GELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIV 400
Query: 554 GNMINQQRDKLFELTKRQEE-YDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEK 612
M + + KL +L +E Y +++ + E+ R + E+ +K E E + +
Sbjct: 401 QRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYS 460
Query: 613 ----EEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVLK 663
E+ + ++N+ N+L ++ + D K K+ L L+LE+ R L+
Sbjct: 461 NITVNEDQIKLMNVAINELNIKLQ---DTNSQKEKLKEELGLILEEKCALQRQLE 512
Score = 41.9 bits (94), Expect = 0.007
Identities = 76/418 (18%), Positives = 181/418 (43%), Gaps = 38/418 (9%)
Query: 275 MKDRLSRAEHQLKTNVERVVQLEAALEQARSE---SWSLERTVXXXXXXXXXXXEDFDQE 331
+KD+L+ A+ L E++VQ ++ + E S ER E+ +
Sbjct: 329 LKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKR 388
Query: 332 LNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEM-NLNIA 390
+K +Q D +E + KL+ Y + I MK E+ ++A
Sbjct: 389 NHKDSQFETDIVQRMEQET--QRKLEQLRAEL-------DEMYGQQIVQMKQELIRQHMA 439
Query: 391 KLIEIEKKYNDSIEEKKTLQENI----DDLRT-DLLESELRVK--DLVRELDE-KES--- 439
++ E++ ++ +E NI D ++ ++ +EL +K D + ++ KE
Sbjct: 440 QMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGL 499
Query: 440 ILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIK-DIXXX 498
ILE K +Q++LE +L + +I+ ++ + E+ +++E LST + +K +I
Sbjct: 500 ILEEKCALQRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSA 559
Query: 499 XXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNL----KNQITQLREFGAFDNLNDVG 554
E K L + + ++ +LR F + ++
Sbjct: 560 SESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELS 619
Query: 555 NMINQ-QRDKLFELTKRQE----EYDEKLQTKENEIKRLVESMT-EQEHVLNKKEKEIKM 608
+ + + + K ++ Y +++ +NE+ + +E+M E+++++ K+ + I
Sbjct: 620 KLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILE 679
Query: 609 LNEKEEEHMNIINLLHNKLELR-NE--ADIDVIITLAKYKKSLTLVLEKMSISNRVLK 663
+++ ++ +++N ++ L+ NE +I+++ K K +L ++++ + +L+
Sbjct: 680 ISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLE 737
Score = 40.3 bits (90), Expect = 0.023
Identities = 51/306 (16%), Positives = 131/306 (42%), Gaps = 36/306 (11%)
Query: 329 DQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLN 388
+ ++ + +I + L+D +EKL+ + + ++D+ E++ +
Sbjct: 466 EDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEE----KCALQRQLEDLVEELSFS 521
Query: 389 ---IAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETK- 444
I + + + + E ++DL+ +++ + K+L + + + + + K
Sbjct: 522 REQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKL 581
Query: 445 QCVQKELESTKTDL-EHRKTEIEEYK-RLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXX 502
+ ++KE + + E ++ E+E + +LLF EE+ +LK L E I
Sbjct: 582 EMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRIN--------- 632
Query: 503 XXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRD 562
+++ Y +++ L+N+++Q E F+ N+I +Q
Sbjct: 633 -------------IEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEK----DNLITKQNQ 675
Query: 563 KLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINL 622
+ E++K ++ + +K E+ + + ++ +L ++EKE L ++ +E L
Sbjct: 676 LILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTEL 735
Query: 623 LHNKLE 628
L +++
Sbjct: 736 LEKQMK 741
Score = 38.3 bits (85), Expect = 0.092
Identities = 130/676 (19%), Positives = 274/676 (40%), Gaps = 77/676 (11%)
Query: 4 EELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVM 63
EEL + Q + + EQES +E+HK + ++V+ +S+KELE +
Sbjct: 516 EELSFSREQIQRAR-QTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELE------L 568
Query: 64 ELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDN 123
+ A + N K+++L ++ N + + A+L + L + E + L+
Sbjct: 569 KHEAEVTNYKIKLEMLEKEKN-AVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEI 627
Query: 124 KVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAEN 183
+ ++ KL + N + ++ + E+ E++ ++ + TK I E +
Sbjct: 628 EHRINIEKLKD--NLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQ-NQLILEISKLK 684
Query: 184 DLLKSSLDQLRTEFLKEINDI---IDCLRKNANETMALQLRTKELSCALSDLNTQNAEMR 240
DL +S ++ E +IN++ I+ LR+ E L+ +EL L T+ E +
Sbjct: 685 DLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQEL-----QLKTELLEKQ 739
Query: 241 KQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNV-----ERVVQ 295
+ D +A SI+KD E LK + ER++
Sbjct: 740 MKEKENDLQEKFAQ-------------LEAENSILKDEKKTLEDMLKIHTPVSQEERLIF 786
Query: 296 LEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKD--NTTHL--EDIAL 351
L++ +++ W E + ED Q+ +L + I+ NT ++ +
Sbjct: 787 LDSIKSKSKDSVWEKEIEI------LIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEV 840
Query: 352 AREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQE 411
++LQ S NK + K ++ + + + +++ +++ K ++
Sbjct: 841 NYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKA-LNEELHLQRINPTTVKMKSSV-- 897
Query: 412 NIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRL 471
D+ +T + E+ L + ++V E D E ++E + ++E K +L R +++ E
Sbjct: 898 -FDEDKTFVAET-LEMGEVV-EKDTTE-LMEKLEVTKRE----KLELSQRLSDLSEQ--- 946
Query: 472 LFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEEL 531
L +K EI L ++ + K K+ R ++S ++
Sbjct: 947 LKQKHGEISFLNEEVKSLKQEKE---------QVSLRCRELEIIINHNRAENVQSCDTQV 997
Query: 532 MNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENE-IKRLVE 590
+L + + + GA +++ V ++ + E E ++K+ + I +
Sbjct: 998 SSLLDGVVTMTSRGAEGSVSKVNKSFGEESKIMVEDKVSFENMTVGEESKQEQLILDHLP 1057
Query: 591 SMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTL 650
S+T++ + + E N+K ++ +N++ N L L+ EA + ++L Y +
Sbjct: 1058 SVTKESSLRATQPSE----NDKLQKELNVLKSEQNDLRLQMEAQ-RICLSLV-YSTHVDQ 1111
Query: 651 VLEKMSISNRVLKCSL 666
V E M CSL
Sbjct: 1112 VREYMENEKDKALCSL 1127
Score = 35.9 bits (79), Expect = 0.49
Identities = 96/461 (20%), Positives = 176/461 (38%), Gaps = 37/461 (8%)
Query: 42 QEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSP 101
++ M E+ K + + Y+++ ++KL+ +N + + L N K
Sbjct: 435 RQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIK-LQDTNSQKEKL 493
Query: 102 EQLLQLCAGGEPKALEHSTLD--NKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFES 159
++ L L E AL+ D +++F ++ ++ ++ E L + + ++ E
Sbjct: 494 KEELGLILE-EKCALQRQLEDLVEELSFSREQIQRARQTIAEQ-ESKLNEAHKSLSTVED 551
Query: 160 LMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNAN---ETM 216
L ++ S +++K AE K L+ L KE N ++D + ++ E +
Sbjct: 552 LKAEIVSASESRKELELKH-EAEVTNYKIKLEMLE----KEKNAVLDRMAESQEAELERL 606
Query: 217 ALQL---RTKELSCALSDLNTQ---NAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXX 270
QL +ELS DL + N E K + G H++ +
Sbjct: 607 RTQLLFSHEEELSKLKEDLEIEHRINIEKLKD-NLGIHYKQQID-----GLQNEMSQKIE 660
Query: 271 XXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQ 330
KD L ++QL + ++ L+ +L ++SE +L+ E
Sbjct: 661 TMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKG 720
Query: 331 ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMK--HEMNLN 388
L + Q ++ T LE +E K+++DM H
Sbjct: 721 TLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQ 780
Query: 389 IAKLI---EIEKKYNDSIEEK--KTLQENIDDLRTDLLESELRVKDLVRELDEKESILET 443
+LI I+ K DS+ EK + L E +DL+ ++ ++ E E
Sbjct: 781 EERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEV 840
Query: 444 K-QCVQKE---LESTKTDLEHRKTEIE-EYKRLLFEKGEEI 479
Q +Q+E L K DLE K + E EYK L EE+
Sbjct: 841 NYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEEL 881
>AB019691-1|BAA78718.1| 3899|Homo sapiens Centrosome- and
Golgi-localized PKN-associated protein (CG-NAP) protein.
Length = 3899
Score = 56.4 bits (130), Expect = 3e-07
Identities = 74/348 (21%), Positives = 150/348 (43%), Gaps = 24/348 (6%)
Query: 330 QELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEM--NL 387
Q+L + ++D ED + LQ + NK K + L
Sbjct: 275 QQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEEL 334
Query: 388 NIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD-----EKESILE 442
N K+IE EKK + ++ T + + +L+ +++ +K++ EL E++S E
Sbjct: 335 N-TKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEE 393
Query: 443 TKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXX 502
KQ + E K + + + E + +R+ E ++++L+++L + +
Sbjct: 394 IKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELI 453
Query: 503 XXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRD 562
E+ ++SY +N ++QI + A + LN N Q++
Sbjct: 454 RQHMAQMEEIKTRHKGEMENALRSYSNITVN-EDQIKLMNV--AINELNIKLQDTNSQKE 510
Query: 563 KLFE-----------LTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNE 611
KL E L ++ E+ E+L +I+R +++ EQE LN+ K + + +
Sbjct: 511 KLKEELGLILEEKCALQRQLEDLVEELSFSRGQIQRARQTIAEQESKLNEAHKSLSTVED 570
Query: 612 KEEEHMNIINLLHNKLELRNEADI-DVIITLAKYKKSLTLVLEKMSIS 658
+ E ++ + +LEL++EA++ + I L +K VL++M+ S
Sbjct: 571 LKAEIVS-ASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAES 617
Score = 51.2 bits (117), Expect = 1e-05
Identities = 74/298 (24%), Positives = 132/298 (44%), Gaps = 32/298 (10%)
Query: 392 LIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVREL---DEKE-SILETKQ-- 445
L E K ++ + K+ LQ +I + ++ + E RV++LV+ L D K +E K
Sbjct: 2118 LKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELVQALLVEDRKHFGAVEAKPEL 2177
Query: 446 CVQKELESTKTDLEHRKTEI-------EEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXX 498
++ +L++ + ++ ++ EI E+++ L K EE+ +L +L +K +
Sbjct: 2178 SLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKK-ESTTRL 2236
Query: 499 XXXXXXXXXXXXXXXXXXXXXRESQMKSYYEE--LMNLKNQITQLREFGAFDNLNDVGNM 556
+ES S ++ L QI Q +E D LN+
Sbjct: 2237 QELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEV-EIDQLNEQVTK 2295
Query: 557 INQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEK-EEE 615
+ QQ K+ K EE +E ++ E +I+ L M++QE V +E+EI+ LNE E+
Sbjct: 2296 LQQQL-KITTDNKVIEEKNELIRDLETQIECL---MSDQECVKRNREEEIEQLNEVIEKL 2351
Query: 616 HMNIINL----LHNKLELRNEAD-----IDVIIT-LAKYKKSLTLVLEKMSISNRVLK 663
+ N+ N L EAD +DV+I ++ + E+M+ VLK
Sbjct: 2352 QQELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLK 2409
Score = 46.4 bits (105), Expect = 3e-04
Identities = 31/110 (28%), Positives = 59/110 (53%), Gaps = 9/110 (8%)
Query: 378 IKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDD--LRTDLLESELRVKDLVRELD 435
+ EM L I +L + + +EK TL++ + + L+T+LLE +++ K+ +L
Sbjct: 710 VNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKE--NDLQ 767
Query: 436 EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSK 485
EK + LE + + K+ + T D+ T + + +RL+F +D +KSK
Sbjct: 768 EKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIF-----LDSIKSK 812
Score = 44.8 bits (101), Expect = 0.001
Identities = 49/235 (20%), Positives = 98/235 (41%), Gaps = 9/235 (3%)
Query: 434 LDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIK 493
L EK + E +Q + E S K +++ ++T IEE + E+ ++ ELK KL+T +
Sbjct: 301 LQEKIKVYEMEQDKKVE-NSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLL 359
Query: 494 DIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDV 553
+E Q ++LM ++ + + + V
Sbjct: 360 GELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIV 419
Query: 554 GNMINQQRDKLFELTKRQEE-YDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEK 612
M + + KL +L +E Y +++ + E+ R + E+ +K E E + +
Sbjct: 420 QRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEIKTRHKGEMENALRSYS 479
Query: 613 ----EEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVLK 663
E+ + ++N+ N+L ++ + D K K+ L L+LE+ R L+
Sbjct: 480 NITVNEDQIKLMNVAINELNIKLQ---DTNSQKEKLKEELGLILEEKCALQRQLE 531
Score = 43.2 bits (97), Expect = 0.003
Identities = 100/495 (20%), Positives = 195/495 (39%), Gaps = 63/495 (12%)
Query: 4 EELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVM 63
EEL + Q + + EQES +E+HK + ++V+ +S+KELE +
Sbjct: 535 EELSFSRGQIQRAR-QTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELE------L 587
Query: 64 ELYASLRNTHRKMKLLGQKVN--LPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTL 121
+ A + N K+++L ++ N L E + +LS QLL K E +
Sbjct: 588 KHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLS-TQLLFSHEEELSKLKEDLEI 646
Query: 122 DNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNA 181
+++++ + KL + N + ++ + E+ E++ ++ + TK I E +
Sbjct: 647 EHRIS--IEKLKD--NLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQ-NQLILEISK 701
Query: 182 ENDLLKSSLDQLRTEFLKEINDI---IDCLRKNANETMALQLRTKELSCALSDLNTQNAE 238
DL +S ++ E +IN++ I+ LR+ E L+ +EL L T+ E
Sbjct: 702 LKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQEL-----QLKTELLE 756
Query: 239 MRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNV-----ERV 293
+ + D +A SI+KD E LK + ER+
Sbjct: 757 KQMKEKENDLQEKFAQ-------------LEAENSILKDEKKTLEDMLKIHTPVSQEERL 803
Query: 294 VQLEAALEQARSESWSLERTVXXXXXXX-----XXXXEDFDQELNKLTQSIKDNTTHLED 348
+ L++ +++ W E + E+ +++ N + + K+ + ++
Sbjct: 804 IFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQE 863
Query: 349 IALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYN-------- 400
+ L Y +K + E+NL ++ K +
Sbjct: 864 LQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEELNLQRINPTTVKMKSSVFDEDKTF 923
Query: 401 --DSIE-----EKKT--LQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKEL 451
+++E EK T L EN++ + + LE R+ DL +L +K + K L
Sbjct: 924 VAETLEMGEVVEKDTTELMENLEVTKREKLELSQRLSDLSEQLKQKHGEISFLNEEVKSL 983
Query: 452 ESTKTDLEHRKTEIE 466
+ K + R E+E
Sbjct: 984 KQEKEQVSLRCRELE 998
Score = 41.9 bits (94), Expect = 0.007
Identities = 77/418 (18%), Positives = 180/418 (43%), Gaps = 38/418 (9%)
Query: 275 MKDRLSRAEHQLKTNVERVVQLEAALEQARSE---SWSLERTVXXXXXXXXXXXEDFDQE 331
+KD+L+ A+ L E++VQ ++ + E S ER E+ +
Sbjct: 348 LKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKR 407
Query: 332 LNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEM-NLNIA 390
+K +Q D +E + KL+ Y + I MK E+ ++A
Sbjct: 408 NHKDSQFETDIVQRMEQET--QRKLEQLRAEL-------DEMYGQQIVQMKQELIRQHMA 458
Query: 391 KLIEIEKKYNDSIEEKKTLQENI----DDLRT-DLLESELRVK--DLVRELDE-KES--- 439
++ EI+ ++ +E NI D ++ ++ +EL +K D + ++ KE
Sbjct: 459 QMEEIKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGL 518
Query: 440 ILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIK-DIXXX 498
ILE K +Q++LE +L + +I+ ++ + E+ +++E LST + +K +I
Sbjct: 519 ILEEKCALQRQLEDLVEELSFSRGQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSA 578
Query: 499 XXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNL-KNQITQLREFGA---FDNLNDVG 554
E K L + ++Q +L F + ++
Sbjct: 579 SESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLSTQLLFSHEEELS 638
Query: 555 NMINQ-QRDKLFELTKRQE----EYDEKLQTKENEIKRLVESMT-EQEHVLNKKEKEIKM 608
+ + + + K ++ Y +++ +NE+ + +E+M E+++++ K+ + I
Sbjct: 639 KLKEDLEIEHRISIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILE 698
Query: 609 LNEKEEEHMNIINLLHNKLELR-NE--ADIDVIITLAKYKKSLTLVLEKMSISNRVLK 663
+++ ++ +++N ++ L+ NE +I+++ K K +L ++++ + +L+
Sbjct: 699 ISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLE 756
Score = 39.5 bits (88), Expect = 0.040
Identities = 51/306 (16%), Positives = 130/306 (42%), Gaps = 36/306 (11%)
Query: 329 DQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLN 388
+ ++ + +I + L+D +EKL+ + + ++D+ E++ +
Sbjct: 485 EDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEE----KCALQRQLEDLVEELSFS 540
Query: 389 ---IAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETK- 444
I + + + + E ++DL+ +++ + K+L + + + + + K
Sbjct: 541 RGQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKL 600
Query: 445 QCVQKELESTKTDL-EHRKTEIEEYK-RLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXX 502
+ ++KE + + E ++ E+E +LLF EE+ +LK L E I
Sbjct: 601 EMLEKEKNAVLDRMAESQEAELERLSTQLLFSHEEELSKLKEDLEIEHRI---------- 650
Query: 503 XXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRD 562
+++ Y +++ L+N+++Q E F+ N+I +Q
Sbjct: 651 ------------SIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEK----DNLITKQNQ 694
Query: 563 KLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINL 622
+ E++K ++ + +K E+ + + ++ +L ++EKE L ++ +E L
Sbjct: 695 LILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTEL 754
Query: 623 LHNKLE 628
L +++
Sbjct: 755 LEKQMK 760
Score = 37.1 bits (82), Expect = 0.21
Identities = 68/366 (18%), Positives = 145/366 (39%), Gaps = 41/366 (11%)
Query: 277 DRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLT 336
D + R E +L R+ +LEA +Q + E L R + QE KL
Sbjct: 1943 DVIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLM 2002
Query: 337 QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIE 396
+ + E + R+ LQ K +K ++ ++ +++ IE+E
Sbjct: 2003 KEKLEVQCQAEKV---RDDLQ------------------KQVKALEIDVEEQVSRFIELE 2041
Query: 397 KKYNDSI----EEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELE 452
++ N + ++ + L++ ++ +R L E + D E D + ++ + K +
Sbjct: 2042 QEKNTELMDLRQQNQALEKQLEKMRKFLDEQAI---DREHERDVFQQEIQKLEQQLKVVP 2098
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXX 512
+ EH+ E+E+ L EK ++ EL LS E+ +DI
Sbjct: 2099 RFQPISEHQTREVEQLANHLKEKTDKCSEL--LLSKEQLQRDI----------QERNEEI 2146
Query: 513 XXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQE 572
RE E+ + + E L + I+++ ++ L ++ E
Sbjct: 2147 EKLEFRVRELVQALLVEDRKHF-GAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLE 2205
Query: 573 EYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNE 632
++ E+L+ K E+++L + Q+ + +E++ N+ ++ M + L + + +
Sbjct: 2206 QFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMST 2265
Query: 633 ADIDVI 638
D V+
Sbjct: 2266 QDQHVL 2271
Score = 36.3 bits (80), Expect = 0.37
Identities = 95/471 (20%), Positives = 182/471 (38%), Gaps = 35/471 (7%)
Query: 42 QEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSP 101
++ M E+ K + + Y+++ ++KL+ +N + + L N K
Sbjct: 454 RQHMAQMEEIKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIK-LQDTNSQKEKL 512
Query: 102 EQLLQLCAGGEPKALEHSTLD--NKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFES 159
++ L L E AL+ D +++F ++ ++ ++ E L + + ++ E
Sbjct: 513 KEELGLILE-EKCALQRQLEDLVEELSFSRGQIQRARQTIAEQ-ESKLNEAHKSLSTVED 570
Query: 160 LMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNAN---ETM 216
L ++ S +++K AE K L+ L KE N ++D + ++ E +
Sbjct: 571 LKAEIVSASESRKELELKH-EAEVTNYKIKLEMLE----KEKNAVLDRMAESQEAELERL 625
Query: 217 ALQL---RTKELSCALSDLNTQNAEMRKQIHS--GDHHRPYANRNXXXXXXXXXXXXXXX 271
+ QL +ELS DL ++ +++ G H++ +
Sbjct: 626 STQLLFSHEEELSKLKEDLEIEHRISIEKLKDNLGIHYKQQID-----GLQNEMSQKIET 680
Query: 272 XSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQE 331
KD L ++QL + ++ L+ +L ++SE +L+ E
Sbjct: 681 MQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGT 740
Query: 332 LNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMK--HEMNLNI 389
L + Q ++ T LE +E K+++DM H
Sbjct: 741 LEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQE 800
Query: 390 AKLI---EIEKKYNDSIEEK--KTLQENIDDLRTDLLESELRVKDLVRELDEKESILETK 444
+LI I+ K DS+ EK + L E +DL+ ++ ++ E E
Sbjct: 801 ERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVN 860
Query: 445 -QCVQKE---LESTKTDLEHRKTEIE-EYKRLLFEKGEEIDELKSKLSTEK 490
Q +Q+E L K DLE K + E EYK L EE++ + +T K
Sbjct: 861 YQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEELNLQRINPTTVK 911
Score = 33.1 bits (72), Expect = 3.5
Identities = 35/199 (17%), Positives = 81/199 (40%), Gaps = 14/199 (7%)
Query: 340 KDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKY 399
++ +E + EKLQ + S ++ +KH++++ IA+ + +E++
Sbjct: 2335 RNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQV 2394
Query: 400 NDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELE-STKTDL 458
++ E+ T +N+ L E+ ++ L +EL + E+ + +Q E S +
Sbjct: 2395 -ETANEEMTFMKNV------LKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVNVAI 2447
Query: 459 EHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXX 518
+H + E + +L E D LKS L + K
Sbjct: 2448 DHLSKDKPELEVVLTE-----DALKS-LENQTYFKSFEENGKGSIINLETRLRQLESTVS 2501
Query: 519 XRESQMKSYYEELMNLKNQ 537
++ ++ Y+++ +++ Q
Sbjct: 2502 AKDLELTQCYKQIKDMQEQ 2520
Score = 32.3 bits (70), Expect = 6.1
Identities = 50/228 (21%), Positives = 95/228 (41%), Gaps = 25/228 (10%)
Query: 276 KDRLSRAEHQLKTNVERVVQLEAALEQAR---SESWSLERTVXXXXXXXXXXXEDFDQEL 332
K+ L + L++ +R +QL LEQ + +ES + + + EL
Sbjct: 3231 KEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLEL 3290
Query: 333 NKLTQS----IKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLN 388
L QS I++ ++ L+ +LQS S K ++ E +
Sbjct: 3291 QVLLQSQKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHSR 3350
Query: 389 IAKLIEIEKKYN-DSIE-----------EKKTLQ---ENIDDLRTDLLESELRVKDLVRE 433
I +L+ +KY DS++ +KTLQ E + + + E + +V+DL R+
Sbjct: 3351 IVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQ 3410
Query: 434 LDEKESILETKQCVQKELESTKTDLEHRKTEIE---EYKRLLFEKGEE 478
L+EK + + L+ + + ++ E E E +R+L++ E
Sbjct: 3411 LEEKRQQVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRILYQNLNE 3458
Score = 31.9 bits (69), Expect = 8.0
Identities = 35/156 (22%), Positives = 74/156 (47%), Gaps = 14/156 (8%)
Query: 520 RESQMKSYYEELMNLKNQITQLREFGAFDNL--NDVGNMINQQRDKLFELTKRQEEYDEK 577
++SQM EL ++K++ T+L+E + + + ++ + + Q + +L K Q ++ ++
Sbjct: 3121 KQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKE 3180
Query: 578 LQTKENEIK------RLVESMTEQEHVLNKK-----EKEIKMLNEKEEEHMNIINLLHNK 626
L+ E+K L+ EH +++ EKE L EE + L
Sbjct: 3181 LEAFRLEVKDKTDEVHLLNDTLASEHKKSRELQWALEKEKAKLGRSEERDKEELEDLKFS 3240
Query: 627 LELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVL 662
LE + + ++ + + L + K+ L +K+ S R+L
Sbjct: 3241 LESQKQRNLQLNLLLEQQKQLLNESQQKIE-SQRML 3275
>D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heavy
chain protein.
Length = 1052
Score = 56.0 bits (129), Expect = 4e-07
Identities = 135/712 (18%), Positives = 276/712 (38%), Gaps = 68/712 (9%)
Query: 13 TDGCLYEDLNEQESITSESHKI-TKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRN 71
++ L E L + + +E+ ++ +L QE + + LE+ +++ +L A +
Sbjct: 2 SENLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKK 61
Query: 72 THRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNK 131
++M L +++ A + + K++ E ++ E + L +NK++ +
Sbjct: 62 MAQQMLDLEEQLEEEEAARQKLQ-LEKVTAEAKIKKL---EDEILVMDDQNNKLSKERKL 117
Query: 132 LLNIPNSLVDKCEETLFKRKEII---NWFESLMSQEKGISTKTLTMKIKEFNAENDLLKS 188
L + L E K K + N ES++S+ + K ++ E + LK
Sbjct: 118 LEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE-----LEVRLKKEEKSRQELEKLKR 172
Query: 189 SLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMR---KQIHS 245
L+ ++F ++I D+ + A M L + +EL AL+ L+ + A+ K+I
Sbjct: 173 KLEGDASDFHEQIADL---QAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRE 229
Query: 246 GDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARS 305
+ H + K L LKT +E + A ++ R+
Sbjct: 230 LEGHISDLQEDLDSERAARNKAEK-----QKRDLGEELEALKTELEDTLDSTATQQELRA 284
Query: 306 ESWSLERTVXXXXXXXXXXXEDFDQELN-KLTQSIKDNTTHLEDIALAREKLQSXXXXXX 364
+ + E QE+ K Q++++ T LE A+ L
Sbjct: 285 KREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLE 344
Query: 365 XXXXXXSASYN---KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTD-- 419
+ ++ ++++H+ A++ E++ K +D + L + + L+ +
Sbjct: 345 KENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVE 404
Query: 420 -----LLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFE 474
L E+E + L +++ S L+ Q + +E K ++ + ++EE + L +
Sbjct: 405 SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQD 464
Query: 475 KGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNL 534
+ +E E+++K + E+ I + E K + +E+ NL
Sbjct: 465 QLDE--EMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEAL----EEGKKRFQKEIENL 518
Query: 535 KNQITQLREFGAFDNLNDVGNMINQQRDKLF-----------ELTKRQEEYDEKLQTKEN 583
Q + + A+D L N + Q+ D L L K+Q ++D+ L ++N
Sbjct: 519 TQQYEE--KAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKN 576
Query: 584 EIKRLVESMTEQEHVLNKKEKEIKMLN---------EKEEEHMNIINLLHNKLELRNEAD 634
+ + E +EKE K L+ E +EE +L ++E +
Sbjct: 577 ISSKYADERDRAE--AEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSK 634
Query: 635 IDV---IITLAKYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRTLRKNMSGL 683
DV + L K K++L +E+M L+ L L NM L
Sbjct: 635 DDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQASEDAKLRLEVNMQAL 686
Score = 48.8 bits (111), Expect = 7e-05
Identities = 112/611 (18%), Positives = 234/611 (38%), Gaps = 37/611 (6%)
Query: 24 QESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQN---QVMELYASLRNTHRKMKLLG 80
QE + + TKL+ + +E+ ++ +E+E +QN + L L ++ +K++
Sbjct: 439 QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFA 498
Query: 81 QKVN-LPSAE---ELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIP 136
V L + + I N+ + E+ + K LD+ V D++ +
Sbjct: 499 STVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV-DLDNQRQLV 557
Query: 137 NSLVDK---CEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQL 193
++L K ++ L + K I + + + + + + T + A + L++ +
Sbjct: 558 SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELE 617
Query: 194 RT-EFLK-EINDII---DCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDH 248
RT + LK E+ D++ D + KN +E L+ + L + ++ TQ E+ ++ + +
Sbjct: 618 RTNKMLKAEMEDLVSSKDDVGKNVHE---LEKSKRALETQMEEMKTQLEELEDELQASED 674
Query: 249 H--RPYANRNXXXXXXXXXXXXXXXXSIMKDR-LSRAEHQLKTNVERVVQLEAALEQARS 305
R N + K R L R H+ +T +E A A+
Sbjct: 675 AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERNERALAAAAKK 734
Query: 306 ESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXX 365
+ + + E+ ++L KL +KD LED +R+++ +
Sbjct: 735 KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK 794
Query: 366 XXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESEL 425
A + +D+ K ++EK+ + EE + + L+ + E
Sbjct: 795 KAKSLEADLMQLQEDLAAAERAR--KQADLEKE--ELAEELASSLSGRNALQDEKRRLEA 850
Query: 426 RVKDLVRELDEKESILET------KQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI 479
R+ L EL+E++ +E K Q E S + E + E R E+ +
Sbjct: 851 RIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNK- 909
Query: 480 DELKSKL-STEKAIKD-IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQ 537
EL+SKL E A+K +++ KS ++ LK
Sbjct: 910 -ELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEI 968
Query: 538 ITQLR-EFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQE 596
+ Q+ E + + N + +L + EE +++ +++R ++ TE
Sbjct: 969 LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESN 1028
Query: 597 HVLNKKEKEIK 607
+ ++ +K
Sbjct: 1029 EAMGREVNALK 1039
Score = 44.4 bits (100), Expect = 0.001
Identities = 104/614 (16%), Positives = 235/614 (38%), Gaps = 35/614 (5%)
Query: 32 HKITKLKTVWQE---KMVTFEKSKKELEDR----QNQVMELYASLRNTHRKMKLLGQKVN 84
HK KL+ QE K E+++ EL D+ QN+V + L K L + V
Sbjct: 366 HKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVA 425
Query: 85 LPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIP---NSLVD 141
S++ + + Q L + E ++L +++ ++ N+ ++L
Sbjct: 426 SLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNI 485
Query: 142 KCEETLFKRKEIINWFESLMSQEKGISTK--TLTMKIKEFNAENDLLKSSLDQLRTEFLK 199
+ ++ K ++ + E+L +K + LT + +E A D L+ + ++L+ +
Sbjct: 486 QLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQ----Q 541
Query: 200 EINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXX 259
E++D++ L L+ + ++ L++ +++ ++ + R A
Sbjct: 542 ELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK-----YADERDRAEAEAREKE 596
Query: 260 XXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXX 319
K+ L R LK +E +V + + + E +R +
Sbjct: 597 TKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME 656
Query: 320 XXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREK-LQSXXXXXXXXXXXXSAS---YN 375
E+ + EL + +++ + E+ LQ+ Y
Sbjct: 657 EMKTQLEELEDELQASEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYE 716
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD 435
++D ++E L A ++E D + + + ++ L + + ++KD REL+
Sbjct: 717 TELEDERNERALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELE 776
Query: 436 E----KESILETKQCVQKELESTKTDLEHRKTEIEEYKRLL----FEKGEEIDELKSKLS 487
+ ++ I T + +K+ +S + DL + ++ +R EK E +EL S LS
Sbjct: 777 DARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLS 836
Query: 488 TEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAF 547
A++D +++ ++ L N++ R A
Sbjct: 837 GRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERS-TAQ 895
Query: 548 DNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQ-EHVLNKKEKEI 606
N + + Q ++ +L + + K ++ ++ + + EQ E +K+
Sbjct: 896 KNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAAT 955
Query: 607 KMLNEKEEEHMNII 620
K L +K+++ I+
Sbjct: 956 KSLKQKDKKLKEIL 969
Score = 44.0 bits (99), Expect = 0.002
Identities = 101/509 (19%), Positives = 197/509 (38%), Gaps = 51/509 (10%)
Query: 2 KQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQ 61
K+EEL+ + D + + N + I I+ L+ + K++K+ D +
Sbjct: 202 KEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEE 261
Query: 62 VMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTL 121
+ L L +T + + L + E + + K E+ A + +H+
Sbjct: 262 LEALKTELEDT---LDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA 318
Query: 122 DNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNA 181
++T + + +L DK ++TL K + ++ Q K + + K K+ A
Sbjct: 319 VEELTEQLEQFKRAKANL-DKNKQTLEKENADLAGELRVLGQAK----QEVEHKKKKLEA 373
Query: 182 ENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRK 241
+ L+S E+ND + K NE ++ E L A +
Sbjct: 374 QVQELQSKCSD-GERARAELNDKV---HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS 429
Query: 242 QIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVER-VVQLEAAL 300
Q+ R S ++D+L E + K N+ER + L L
Sbjct: 430 QLQDTQELLQEETRQKLNVSTKLRQLEEERNS-LQDQLDE-EMEAKQNLERHISTLNIQL 487
Query: 301 EQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXX 360
++ + TV + F +E+ LTQ ++ + + + +LQ
Sbjct: 488 SDSKKKLQDFASTV----EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQ-- 541
Query: 361 XXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDL 420
+ + D+ ++ L ++ L + ++K++ + E+K + D R D
Sbjct: 542 ------------ELDDLVVDLDNQRQL-VSNLEKKQRKFDQLLAEEKNISSKYADER-DR 587
Query: 421 LESELRVKD-----LVRELDE----KESILETKQCVQKELE---STKTDLEHRKTEIEEY 468
E+E R K+ L R L+E KE + T + ++ E+E S+K D+ E+E+
Sbjct: 588 AEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKS 647
Query: 469 KRLLFEKGEE----IDELKSKLSTEKAIK 493
KR L + EE ++EL+ +L + K
Sbjct: 648 KRALETQMEEMKTQLEELEDELQASEDAK 676
>AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein.
Length = 2069
Score = 56.0 bits (129), Expect = 4e-07
Identities = 77/396 (19%), Positives = 166/396 (41%), Gaps = 32/396 (8%)
Query: 275 MKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNK 334
++++L + HQ ++ R+++LE L + E + + ++ + +L
Sbjct: 875 LEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTA 934
Query: 335 LTQS-------IKDNTTHLEDI-ALAREKLQSXXXXXXXXXXXXSASYNKS--IKDMKHE 384
L + ++ T LE+ A A E++Q+ A N I D++ +
Sbjct: 935 LQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQ 994
Query: 385 MNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETK 444
+N E+ N + K L E ++++ V L RE+ E+E L ++
Sbjct: 995 LNQLTEDNAELN---NQNFYLSKQLDE-ASGANDEIVQLRSEVDHLRREITEREMQLTSQ 1050
Query: 445 QCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA-----IKDIXXXX 499
+ + L++T T LE + ++E L EK + + +S L EK+ ++++
Sbjct: 1051 KQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRML 1110
Query: 500 XXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQ--LREFGAFDNLNDVGNMI 557
E +K + E++ L+ + + L+ D LND+
Sbjct: 1111 DTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDL---- 1166
Query: 558 NQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHM 617
+++ + E+ R +KL+T+ +RL+E + + ++ ++ I L + +E +
Sbjct: 1167 -EKKHAMLEMNAR--SLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEAL 1223
Query: 618 NIINLL---HNKLELRNEADIDVIITLAKYKKSLTL 650
+ +LL + LE + E +I V+ + K K T+
Sbjct: 1224 DRADLLKTERSDLEYQLE-NIQVLYSHEKVKMEGTI 1258
Score = 48.8 bits (111), Expect = 7e-05
Identities = 65/279 (23%), Positives = 122/279 (43%), Gaps = 36/279 (12%)
Query: 383 HEMNLNIAKLIEI-EKKYNDSIEEKKTLQENID-DL-----RTDLLESELRVKDLVRELD 435
H++ KL EI E++Y +EE + + ++ DL R+DL ESELR L E +
Sbjct: 540 HDIREQSRKLQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAE-E 598
Query: 436 EKESILETKQCVQKELESTKTDL-EHRKTE-IEEYKRLLFEKGEEIDELKSKLSTE--KA 491
K E + + K + K ++ E+ K E I ++L ++ +E E K STE +
Sbjct: 599 FKRKATECQHKLLKAKDQGKPEVGEYAKLEKINAEQQLKIQELQEKLEKAVKASTEATEL 658
Query: 492 IKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQL-----REFGA 546
+++I R+ +++ E +L+N++ +L RE
Sbjct: 659 LQNIRQAKERAERELEKLQNREDSSEGIRKKLVEAE-ERRHSLENKVKRLETMERRENRL 717
Query: 547 FDNLNDVGNMINQQRDKLFELTKRQEE------------------YDEKLQTKENEIKRL 588
D++ I Q DK+ EL ++ E Y+EK++ +N+IK+
Sbjct: 718 KDDIQTKSQQIQQMADKILELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKD 777
Query: 589 VESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKL 627
+ E+++ + E+E + E +IN + +K+
Sbjct: 778 LADKETLENMMQRHEEEAHEKGKILSEQKAMINAMDSKI 816
Score = 38.7 bits (86), Expect = 0.070
Identities = 76/471 (16%), Positives = 175/471 (37%), Gaps = 21/471 (4%)
Query: 148 FKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDC 207
FKRK + L ++++G K+++ NAE L L + + +K + +
Sbjct: 599 FKRKATECQHKLLKAKDQGKPEVGEYAKLEKINAEQQLKIQELQEKLEKAVKASTEATEL 658
Query: 208 LRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXX 267
L+ N A + +EL L + + +RK++ + R +
Sbjct: 659 LQ---NIRQAKERAERELE-KLQNREDSSEGIRKKLVEAEERR-----HSLENKVKRLET 709
Query: 268 XXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXED 327
+ +KD + Q++ +++++LE +A+ + LE + +
Sbjct: 710 MERRENRLKDDIQTKSQQIQQMADKILELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKV 769
Query: 328 FDQELNK---LTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHE 384
D ++ K +++++ E+ A + K+ S S + I ++
Sbjct: 770 LDNQIKKDLADKETLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEA 829
Query: 385 MNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDE--KESILE 442
L + ++ E L++ L T + E + + L +L++ + +
Sbjct: 830 NKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSD 889
Query: 443 TKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKL----STEKAIKDIXXX 498
+ ++ E + LEH + ++ E KR L E + E +S+L + A++
Sbjct: 890 KNRLLELETRLREVSLEHEEQKL-ELKRQLTELQLSLQERESQLTALQAARAALESQLRQ 948
Query: 499 XXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMIN 558
+++ ++ L N IT L E + L + +N
Sbjct: 949 AKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEE--QLNQLTEDNAELN 1006
Query: 559 QQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKML 609
Q L + ++++ +E+ L +TE+E L +++ ++ L
Sbjct: 1007 NQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEAL 1057
>AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting citron
kinase protein.
Length = 2027
Score = 56.0 bits (129), Expect = 4e-07
Identities = 77/396 (19%), Positives = 166/396 (41%), Gaps = 32/396 (8%)
Query: 275 MKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNK 334
++++L + HQ ++ R+++LE L + E + + ++ + +L
Sbjct: 833 LEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTA 892
Query: 335 LTQS-------IKDNTTHLEDI-ALAREKLQSXXXXXXXXXXXXSASYNKS--IKDMKHE 384
L + ++ T LE+ A A E++Q+ A N I D++ +
Sbjct: 893 LQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQ 952
Query: 385 MNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETK 444
+N E+ N + K L E ++++ V L RE+ E+E L ++
Sbjct: 953 LNQLTEDNAELN---NQNFYLSKQLDE-ASGANDEIVQLRSEVDHLRREITEREMQLTSQ 1008
Query: 445 QCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA-----IKDIXXXX 499
+ + L++T T LE + ++E L EK + + +S L EK+ ++++
Sbjct: 1009 KQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRML 1068
Query: 500 XXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQ--LREFGAFDNLNDVGNMI 557
E +K + E++ L+ + + L+ D LND+
Sbjct: 1069 DTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDL---- 1124
Query: 558 NQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHM 617
+++ + E+ R +KL+T+ +RL+E + + ++ ++ I L + +E +
Sbjct: 1125 -EKKHAMLEMNAR--SLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEAL 1181
Query: 618 NIINLL---HNKLELRNEADIDVIITLAKYKKSLTL 650
+ +LL + LE + E +I V+ + K K T+
Sbjct: 1182 DRADLLKTERSDLEYQLE-NIQVLYSHEKVKMEGTI 1216
Score = 46.0 bits (104), Expect = 5e-04
Identities = 57/256 (22%), Positives = 115/256 (44%), Gaps = 32/256 (12%)
Query: 383 HEMNLNIAKLIEI-EKKYNDSIEEKKTLQENID-DL-----RTDLLESELRVKDLVRELD 435
H++ KL EI E++Y +EE + + ++ DL R+DL ESELR L E
Sbjct: 540 HDIREQSRKLQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEF 599
Query: 436 EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEE---IDELKSKLSTEKAI 492
++++ +C K L++ + K E+ EY +L E+ I EL+ KL EKA+
Sbjct: 600 KRKAT----ECQHKLLKAK----DQGKPEVGEYAKLEKINAEQQLKIQELQEKL--EKAV 649
Query: 493 KDIXXXXXXXXXXXXXXXXXXXXXXXXRE-SQMKSYYEELMNLKNQITQLREFGAFDNLN 551
K RE ++++ + ++ ++ + E + +
Sbjct: 650 K------ASTEATELLQNIRQAKERAERELEKLQNREDSSEGIRKKLVEAEEL---EEKH 700
Query: 552 DVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNE 611
+ Q + L ++++ Y+EK++ +N+IK+ + E+++ + E+E +
Sbjct: 701 REAQVSAQHLE--VHLKQKEQHYEEKIKVLDNQIKKDLADKETLENMMQRHEEEAHEKGK 758
Query: 612 KEEEHMNIINLLHNKL 627
E +IN + +K+
Sbjct: 759 ILSEQKAMINAMDSKI 774
>AC002563-2|AAB71327.1| 1286|Homo sapiens WUGSC:H_127H14.1 protein.
Length = 1286
Score = 56.0 bits (129), Expect = 4e-07
Identities = 77/396 (19%), Positives = 166/396 (41%), Gaps = 32/396 (8%)
Query: 275 MKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNK 334
++++L + HQ ++ R+++LE L + E + + ++ + +L
Sbjct: 107 LEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTA 166
Query: 335 LTQS-------IKDNTTHLEDI-ALAREKLQSXXXXXXXXXXXXSASYNKS--IKDMKHE 384
L + ++ T LE+ A A E++Q+ A N I D++ +
Sbjct: 167 LQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQ 226
Query: 385 MNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETK 444
+N E+ N + K L E ++++ V L RE+ E+E L ++
Sbjct: 227 LNQLTEDNAELN---NQNFYLSKQLDE-ASGANDEIVQLRSEVDHLRREITEREMQLTSQ 282
Query: 445 QCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA-----IKDIXXXX 499
+ + L++T T LE + ++E L EK + + +S L EK+ ++++
Sbjct: 283 KQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRML 342
Query: 500 XXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQ--LREFGAFDNLNDVGNMI 557
E +K + E++ L+ + + L+ D LND+
Sbjct: 343 DTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDL---- 398
Query: 558 NQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHM 617
+++ + E+ R +KL+T+ +RL+E + + ++ ++ I L + +E +
Sbjct: 399 -EKKHAMLEMNAR--SLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEAL 455
Query: 618 NIINLL---HNKLELRNEADIDVIITLAKYKKSLTL 650
+ +LL + LE + E +I V+ + K K T+
Sbjct: 456 DRADLLKTERSDLEYQLE-NIQVLYSHEKVKMEGTI 490
>AB023166-1|BAA76793.2| 1559|Homo sapiens KIAA0949 protein protein.
Length = 1559
Score = 56.0 bits (129), Expect = 4e-07
Identities = 77/396 (19%), Positives = 166/396 (41%), Gaps = 32/396 (8%)
Query: 275 MKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNK 334
++++L + HQ ++ R+++LE L + E + + ++ + +L
Sbjct: 381 LEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTA 440
Query: 335 LTQS-------IKDNTTHLEDI-ALAREKLQSXXXXXXXXXXXXSASYNKS--IKDMKHE 384
L + ++ T LE+ A A E++Q+ A N I D++ +
Sbjct: 441 LQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQ 500
Query: 385 MNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETK 444
+N E+ N + K L E ++++ V L RE+ E+E L ++
Sbjct: 501 LNQLTEDNAELN---NQNFYLSKQLDE-ASGANDEIVQLRSEVDHLRREITEREMQLTSQ 556
Query: 445 QCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA-----IKDIXXXX 499
+ + L++T T LE + ++E L EK + + +S L EK+ ++++
Sbjct: 557 KQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRML 616
Query: 500 XXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQ--LREFGAFDNLNDVGNMI 557
E +K + E++ L+ + + L+ D LND+
Sbjct: 617 DTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDL---- 672
Query: 558 NQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHM 617
+++ + E+ R +KL+T+ +RL+E + + ++ ++ I L + +E +
Sbjct: 673 -EKKHAMLEMNAR--SLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEAL 729
Query: 618 NIINLL---HNKLELRNEADIDVIITLAKYKKSLTL 650
+ +LL + LE + E +I V+ + K K T+
Sbjct: 730 DRADLLKTERSDLEYQLE-NIQVLYSHEKVKMEGTI 764
Score = 46.0 bits (104), Expect = 5e-04
Identities = 57/256 (22%), Positives = 115/256 (44%), Gaps = 32/256 (12%)
Query: 383 HEMNLNIAKLIEI-EKKYNDSIEEKKTLQENID-DL-----RTDLLESELRVKDLVRELD 435
H++ KL EI E++Y +EE + + ++ DL R+DL ESELR L E
Sbjct: 88 HDIREQSRKLQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEF 147
Query: 436 EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEE---IDELKSKLSTEKAI 492
++++ +C K L++ + K E+ EY +L E+ I EL+ KL EKA+
Sbjct: 148 KRKAT----ECQHKLLKAK----DQGKPEVGEYAKLEKINAEQQLKIQELQEKL--EKAV 197
Query: 493 KDIXXXXXXXXXXXXXXXXXXXXXXXXRE-SQMKSYYEELMNLKNQITQLREFGAFDNLN 551
K RE ++++ + ++ ++ + E + +
Sbjct: 198 K------ASTEATELLQNIRQAKERAERELEKLQNREDSSEGIRKKLVEAEEL---EEKH 248
Query: 552 DVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNE 611
+ Q + L ++++ Y+EK++ +N+IK+ + E+++ + E+E +
Sbjct: 249 REAQVSAQHLE--VHLKQKEQHYEEKIKVLDNQIKKDLADKETLENMMQRHEEEAHEKGK 306
Query: 612 KEEEHMNIINLLHNKL 627
E +IN + +K+
Sbjct: 307 ILSEQKAMINAMDSKI 322
>AL139421-3|CAI22510.1| 1044|Homo sapiens coiled-coil domain
containing 18 protein.
Length = 1044
Score = 55.6 bits (128), Expect = 6e-07
Identities = 108/605 (17%), Positives = 241/605 (39%), Gaps = 47/605 (7%)
Query: 19 EDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKL 78
E++ + E++ + +++++ ++ E K+EL NQ L + +++K
Sbjct: 449 ENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQ---LEGNKEKFEKQLKK 505
Query: 79 LGQKVNLPSAEELHIMNVA-KLSPEQ--LLQLCAGGEPKALEHSTLDNKVTFDVNKLLNI 135
++V +EL I N + + + EQ +LQ + + L+ T+ N D L
Sbjct: 506 KSEEVYCLQ-KELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLE- 563
Query: 136 PNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKT-----LTMKIKEFNAENDLLKSSL 190
V K E+ L K++E + E L E+ + K+ E +K +
Sbjct: 564 --KQVSKLEQELQKQRE--SSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEM 619
Query: 191 DQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHR 250
DQ + E K +I+ R N+ M L L ++L + + K++ H
Sbjct: 620 DQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAV-KELEKLQH-- 676
Query: 251 PYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQAR---SES 307
+++ L A +LK+ + ++ +L L++A+ E
Sbjct: 677 ---------STETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEK 727
Query: 308 WSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKL----QSXXXXX 363
++ + + ED QEL ++ Q++K+ L+ A L +
Sbjct: 728 YTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEM 787
Query: 364 XXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTL----QENIDDLRTD 419
+ KS ++K E N I L + + + + EK+ + ++ I L+ +
Sbjct: 788 EQKIIKLEGTLEKSELELK-ECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKE 846
Query: 420 LLESELRVKDLVRELDEKESILET--KQCVQ--KELESTKTDLEHRKTEIEEYKRLLFEK 475
+ ++ R+K++ + E+E + T K+ + +EL T+ +++ TE+ E + +
Sbjct: 847 IERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQA 906
Query: 476 GEEIDELKSKLSTEKAI-KDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNL 534
EI+ L S+L K + K+ ++++K E+ +L
Sbjct: 907 QREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAEVESL 966
Query: 535 KNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTE 594
K + + +N + Q+ + +L ++ E+ +L+ ++ + L + + +
Sbjct: 967 K-EAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQD 1025
Query: 595 QEHVL 599
+ V+
Sbjct: 1026 RNEVI 1030
Score = 54.4 bits (125), Expect = 1e-06
Identities = 99/622 (15%), Positives = 250/622 (40%), Gaps = 36/622 (5%)
Query: 24 QESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKV 83
+ +T + ++ L+ +EK+V + + + + ++ME +R+ + +K+
Sbjct: 316 ESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKI 375
Query: 84 NL--PSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSL-- 139
L A+++H+ ++ +Q+ +L A E K + + ++ ++ + L
Sbjct: 376 CLAFEKAKKIHLEQHKEME-KQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLES 434
Query: 140 VDK--CEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEF 197
+D+ E +KE + E+L + + +S +T+ K+++ ++ ++ K L +
Sbjct: 435 LDRLLTESKGEMKKENMKKDEALKALQNQVSEETI--KVRQLDSALEICKEELVLHLNQL 492
Query: 198 LKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNX 257
L+K + E LQ K + +L + + QN ++ H+ + +
Sbjct: 493 EGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQ---HTLQQQQQMLQQET 549
Query: 258 XXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXX 317
+ K + Q +++ E++ ++E E A E+ + V
Sbjct: 550 IRNGELEDTQTKLEKQVSKLE-QELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIEL 608
Query: 318 XXXXXXXXEDFDQ---ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASY 374
+ DQ EL+K+ + I E+ A+ +L + +
Sbjct: 609 TGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAV 668
Query: 375 NKSIKDMKHEMNLNIAKLIE----IEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDL 430
K ++ ++H + + ++ +E + ++ E K+ + +LR L +++L
Sbjct: 669 -KELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQL----- 722
Query: 431 VRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS-TE 489
L+EK + ++ + EL K ++E +K E+ E + L E+ E+ + ++++ +
Sbjct: 723 --SLEEKYTTIKD---LTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLD 777
Query: 490 KAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDN 549
I++ Q++S ++L N K Q+ + +EF N
Sbjct: 778 MTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLRE-KEFIMLQN 836
Query: 550 LNDVGNM---INQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEI 606
++ + I + + ++ E+ +E ++ + T+ E L + + + E+
Sbjct: 837 EQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTEL 896
Query: 607 KMLNEKEEEHMNIINLLHNKLE 628
++ + I L ++LE
Sbjct: 897 AEARHQQVQAQREIERLSSELE 918
Score = 47.2 bits (107), Expect = 2e-04
Identities = 85/509 (16%), Positives = 198/509 (38%), Gaps = 38/509 (7%)
Query: 172 LTMKIKEFNAENDLLK-------SSLDQLRTEFLKEIND---IIDCLRKNANETMALQLR 221
L K+ + AEN LK S ++ E L++ ++ + + K ++ + L+ +
Sbjct: 273 LRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQ 332
Query: 222 TKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSR 281
+E A S + +NAE+ +++ + N I ++
Sbjct: 333 LEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKE 392
Query: 282 AEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKD 341
E Q++ +LEA LE+ + E+T+ L L + + +
Sbjct: 393 MEKQIE-------RLEAQLEKKDQQFKEQEKTMSMLQQDIICK----QHHLESLDRLLTE 441
Query: 342 NTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLI----EIEK 397
+ ++ + +++ + +++ K E+ L++ +L + EK
Sbjct: 442 SKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEK 501
Query: 398 KYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTD 457
+ EE LQ+ + L E+ + L L +++ +L+ + ELE T+T
Sbjct: 502 QLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTK 561
Query: 458 LEHRKTEIE-EYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXX 516
LE + +++E E ++ E++ +++ K + D+
Sbjct: 562 LEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQV------ 615
Query: 517 XXXRESQMKSYYEELMNLKNQITQLREFGAFD--NLNDVGNMINQQRDKLFELTKRQEEY 574
+ +M Y EEL ++ +I L+ G +L+ + +++Q + +L + T +E
Sbjct: 616 ----KIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKEL 671
Query: 575 DEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEAD 634
++ + E E+ ++ E L E+K + +E +++ LE +
Sbjct: 672 EKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTI 731
Query: 635 IDVIITLAKYKKSLTLVLEKMSISNRVLK 663
D+ L + K + +++ ++ LK
Sbjct: 732 KDLTAELRECKMEIEDKKQELLEMDQALK 760
Score = 42.7 bits (96), Expect = 0.004
Identities = 125/675 (18%), Positives = 264/675 (39%), Gaps = 59/675 (8%)
Query: 3 QEELEIQQNQTDGCLYEDLNEQESITSES-HKITKLKTVWQEKMVT-FEKSKKELEDRQN 60
QE ++ +T+ ES+ ++ H + K ++++VT E+ + +L +
Sbjct: 223 QESSKLSSLETEPVKLGGHQVAESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEA 282
Query: 61 QVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHST 120
+ +L ++ + + +L+ +++ ++ + + QLL L E K + +S+
Sbjct: 283 ENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSS 342
Query: 121 LDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFN 180
+ K ++ + L N + E + E I ++ EK + K + KE
Sbjct: 343 IAAK-NAELEQELMEKNEKIRSLETNINTEHEKI-----CLAFEK--AKKIHLEQHKEME 394
Query: 181 AENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMR 240
+ + L++ L++ +F KE + L++ + + Q + L L++ EM+
Sbjct: 395 KQIERLEAQLEKKDQQF-KEQEKTMSMLQQ---DIICKQHHLESLDRLLTE---SKGEMK 447
Query: 241 KQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAAL 300
K+ D A +N I K+ L +QL+ N E+ E L
Sbjct: 448 KENMKKDEALK-ALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEK---FEKQL 503
Query: 301 EQARSESWSLERTVXXXXXXXXXXXED---FDQELNKLTQSIKDNTTH---LEDIALARE 354
++ E + L++ + E L + Q ++ T LED E
Sbjct: 504 KKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLE 563
Query: 355 KLQSXXXXXXXXXXXXSASYNKSIKDM----KHEMNLNIAKLIE-------IEKKYNDSI 403
K S SA + +++ HE +L K+IE ++ + +
Sbjct: 564 KQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYK 623
Query: 404 EEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKT 463
EE +++ I L+ D + + L LD+ ++ LE K KELE + E T
Sbjct: 624 EELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELT 683
Query: 464 EIEEYKRLL-FEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRES 522
E + + +L E ELKS L + ++D+ +
Sbjct: 684 EALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKM 743
Query: 523 QMKSYYEELMN----LKNQITQLREFGAFDNLNDV------GNM----------INQQRD 562
+++ +EL+ LK + +L++ A D+ G M + +
Sbjct: 744 EIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSEL 803
Query: 563 KLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINL 622
+L E K+ E ++KLQ + +++ M + E +++ +KEI+ ++ +E +++
Sbjct: 804 ELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKE 863
Query: 623 LHNKLELRNEADIDV 637
+ + + ID+
Sbjct: 864 QEQYIATQYKEAIDL 878
>AF083037-1|AAD22767.1| 3595|Homo sapiens A-kinase anchoring protein
AKAP350 protein.
Length = 3595
Score = 55.6 bits (128), Expect = 6e-07
Identities = 62/285 (21%), Positives = 131/285 (45%), Gaps = 21/285 (7%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD-----EKESILETKQ 445
K+IE EKK + ++ T + + +L+ +++ +K++ EL E++S E KQ
Sbjct: 27 KIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQ 86
Query: 446 CVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXX 505
+ E K + + + E + +R+ E ++++L+++L + +
Sbjct: 87 LMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQH 146
Query: 506 XXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLF 565
E+ ++SY +N ++QI + A + LN N Q++KL
Sbjct: 147 MAQMEEMKTRHKGEMENALRSYSNITVN-EDQIKLMNV--AINELNIKLQDTNSQKEKLK 203
Query: 566 E-----------LTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEE 614
E L ++ E+ E+L +I+R +++ EQE LN+ K + + + +
Sbjct: 204 EELGLILEEKCALQRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKA 263
Query: 615 EHMNIINLLHNKLELRNEADI-DVIITLAKYKKSLTLVLEKMSIS 658
E ++ + +LEL++EA++ + I L +K VL++M+ S
Sbjct: 264 EIVS-ASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAES 307
Score = 46.4 bits (105), Expect = 3e-04
Identities = 31/110 (28%), Positives = 59/110 (53%), Gaps = 9/110 (8%)
Query: 378 IKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDD--LRTDLLESELRVKDLVRELD 435
+ EM L I +L + + +EK TL++ + + L+T+LLE +++ K+ +L
Sbjct: 400 VNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKE--NDLQ 457
Query: 436 EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSK 485
EK + LE + + K+ + T D+ T + + +RL+F +D +KSK
Sbjct: 458 EKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIF-----LDSIKSK 502
Score = 42.7 bits (96), Expect = 0.004
Identities = 67/290 (23%), Positives = 127/290 (43%), Gaps = 26/290 (8%)
Query: 394 EIEKKYNDSIEEKKTLQENIDDLRTDLLESE---LRVKDLVR--ELDEKESI-LETK-QC 446
++++ + EE + L+ + +L LL S +V+D ++ K + LE + Q
Sbjct: 1822 QLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPELSLEVQLQA 1881
Query: 447 VQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXX 506
+ ++ + ++ + + ++E+++ L K EE+ +L +L +K +
Sbjct: 1882 ERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKK-ESTTRLQELEQENK 1940
Query: 507 XXXXXXXXXXXXXRESQMKSYYEE--LMNLKNQITQLREFGAFDNLNDVGNMINQQRDKL 564
+ES S ++ L QI Q +E D LN+ + QQ K+
Sbjct: 1941 LFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEV-EIDQLNEQVTKLQQQL-KI 1998
Query: 565 FELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEK-EEEHMNIINL- 622
K EE +E ++ E +I+ L M++QE V +E+EI+ LNE E+ + N+
Sbjct: 1999 TTDNKVIEEKNELIRDLETQIECL---MSDQECVKRNREEEIEQLNEVIEKLQQELANIG 2055
Query: 623 ---LHNKLELRNEAD-----IDVIIT-LAKYKKSLTLVLEKMSISNRVLK 663
N L EAD +DV+I ++ + E+M+ VLK
Sbjct: 2056 QKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLK 2105
Score = 41.9 bits (94), Expect = 0.007
Identities = 76/418 (18%), Positives = 181/418 (43%), Gaps = 38/418 (9%)
Query: 275 MKDRLSRAEHQLKTNVERVVQLEAALEQARSE---SWSLERTVXXXXXXXXXXXEDFDQE 331
+KD+L+ A+ L E++VQ ++ + E S ER E+ +
Sbjct: 38 LKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKR 97
Query: 332 LNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEM-NLNIA 390
+K +Q D +E + KL+ Y + I MK E+ ++A
Sbjct: 98 NHKDSQFETDIVQRMEQET--QRKLEQLRAEL-------DEMYGQQIVQMKQELIRQHMA 148
Query: 391 KLIEIEKKYNDSIEEKKTLQENI----DDLRT-DLLESELRVK--DLVRELDE-KES--- 439
++ E++ ++ +E NI D ++ ++ +EL +K D + ++ KE
Sbjct: 149 QMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGL 208
Query: 440 ILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIK-DIXXX 498
ILE K +Q++LE +L + +I+ ++ + E+ +++E LST + +K +I
Sbjct: 209 ILEEKCALQRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSA 268
Query: 499 XXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNL----KNQITQLREFGAFDNLNDVG 554
E K L + + ++ +LR F + ++
Sbjct: 269 SESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELS 328
Query: 555 NMINQ-QRDKLFELTKRQE----EYDEKLQTKENEIKRLVESMT-EQEHVLNKKEKEIKM 608
+ + + + K ++ Y +++ +NE+ + +E+M E+++++ K+ + I
Sbjct: 329 KLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILE 388
Query: 609 LNEKEEEHMNIINLLHNKLELR-NE--ADIDVIITLAKYKKSLTLVLEKMSISNRVLK 663
+++ ++ +++N ++ L+ NE +I+++ K K +L ++++ + +L+
Sbjct: 389 ISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLE 446
Score = 41.1 bits (92), Expect = 0.013
Identities = 45/221 (20%), Positives = 93/221 (42%), Gaps = 9/221 (4%)
Query: 449 KELE-STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXX 507
K++E S K +++ ++T IEE + E+ ++ ELK KL+T +
Sbjct: 4 KKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEI 63
Query: 508 XXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFEL 567
+E Q ++LM ++ + + + V M + + KL +L
Sbjct: 64 KNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQL 123
Query: 568 TKRQEE-YDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEK----EEEHMNIINL 622
+E Y +++ + E+ R + E+ +K E E + + E+ + ++N+
Sbjct: 124 RAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNV 183
Query: 623 LHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVLK 663
N+L ++ + D K K+ L L+LE+ R L+
Sbjct: 184 AINELNIKLQ---DTNSQKEKLKEELGLILEEKCALQRQLE 221
Score = 40.7 bits (91), Expect = 0.017
Identities = 47/267 (17%), Positives = 115/267 (43%), Gaps = 12/267 (4%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSI----EEKKTLQENIDDLRTDLLESELRVKDLV 431
K +K ++ ++ +++ IE+E++ N + ++ + L++ ++ +R L E + D
Sbjct: 1709 KQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAI---DRE 1765
Query: 432 RELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
E D + ++ + K + + EH+ E+E+ L EK ++ EL LS E+
Sbjct: 1766 HERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSEL--LLSKEQL 1823
Query: 492 IKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLN 551
+DI ++ K E+ + + E L
Sbjct: 1824 QRDIQERNEEIEKLEFRVRELEQALLVSADTFQK--VEDRKHF-GAVEAKPELSLEVQLQ 1880
Query: 552 DVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNE 611
+ I+++ ++ L ++ E++ E+L+ K E+++L + Q+ + +E++ N+
Sbjct: 1881 AERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENK 1940
Query: 612 KEEEHMNIINLLHNKLELRNEADIDVI 638
++ M + L + + + D V+
Sbjct: 1941 LFKDDMEKLGLAIKESDAMSTQDQHVL 1967
Score = 38.3 bits (85), Expect = 0.092
Identities = 130/676 (19%), Positives = 274/676 (40%), Gaps = 77/676 (11%)
Query: 4 EELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVM 63
EEL + Q + + EQES +E+HK + ++V+ +S+KELE +
Sbjct: 225 EELSFSREQIQRAR-QTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELE------L 277
Query: 64 ELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDN 123
+ A + N K+++L ++ N + + A+L + L + E + L+
Sbjct: 278 KHEAEVTNYKIKLEMLEKEKN-AVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEI 336
Query: 124 KVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAEN 183
+ ++ KL + N + ++ + E+ E++ ++ + TK I E +
Sbjct: 337 EHRINIEKLKD--NLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQ-NQLILEISKLK 393
Query: 184 DLLKSSLDQLRTEFLKEINDI---IDCLRKNANETMALQLRTKELSCALSDLNTQNAEMR 240
DL +S ++ E +IN++ I+ LR+ E L+ +EL L T+ E +
Sbjct: 394 DLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQEL-----QLKTELLEKQ 448
Query: 241 KQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNV-----ERVVQ 295
+ D +A SI+KD E LK + ER++
Sbjct: 449 MKEKENDLQEKFAQ-------------LEAENSILKDEKKTLEDMLKIHTPVSQEERLIF 495
Query: 296 LEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKD--NTTHL--EDIAL 351
L++ +++ W E + ED Q+ +L + I+ NT ++ +
Sbjct: 496 LDSIKSKSKDSVWEKEIEI------LIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEV 549
Query: 352 AREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQE 411
++LQ S NK + K ++ + + + +++ +++ K ++
Sbjct: 550 NYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKA-LNEELHLQRINPTTVKMKSSV-- 606
Query: 412 NIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRL 471
D+ +T + E+ L + ++V E D E ++E + ++E K +L R +++ E
Sbjct: 607 -FDEDKTFVAET-LEMGEVV-EKDTTE-LMEKLEVTKRE----KLELSQRLSDLSEQ--- 655
Query: 472 LFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEEL 531
L +K EI L ++ + K K+ R ++S ++
Sbjct: 656 LKQKHGEISFLNEEVKSLKQEKE---------QVSLRCRELEIIINHNRAENVQSCDTQV 706
Query: 532 MNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENE-IKRLVE 590
+L + + + GA +++ V ++ + E E ++K+ + I +
Sbjct: 707 SSLLDGVVTMTSRGAEGSVSKVNKSFGEESKIMVEDKVSFENMTVGEESKQEQLILDHLP 766
Query: 591 SMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTL 650
S+T++ + + E N+K ++ +N++ N L L+ EA + ++L Y +
Sbjct: 767 SVTKESSLRATQPSE----NDKLQKELNVLKSEQNDLRLQMEAQ-RICLSLV-YSTHVDQ 820
Query: 651 VLEKMSISNRVLKCSL 666
V E M CSL
Sbjct: 821 VREYMENEKDKALCSL 836
Score = 35.9 bits (79), Expect = 0.49
Identities = 21/89 (23%), Positives = 48/89 (53%), Gaps = 6/89 (6%)
Query: 394 EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELES 453
++E + I+EK+T+ I++L T ++E E + +L +L + +L +Q+++
Sbjct: 5 KVENSNKEEIQEKETI---IEELNTKIIEEEKKTLELKDKLTTADKLLGE---LQEQIVQ 58
Query: 454 TKTDLEHRKTEIEEYKRLLFEKGEEIDEL 482
++++ K E+ K+ + EEI +L
Sbjct: 59 KNQEIKNMKLELTNSKQKERQSSEEIKQL 87
Score = 35.9 bits (79), Expect = 0.49
Identities = 96/461 (20%), Positives = 176/461 (38%), Gaps = 37/461 (8%)
Query: 42 QEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSP 101
++ M E+ K + + Y+++ ++KL+ +N + + L N K
Sbjct: 144 RQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIK-LQDTNSQKEKL 202
Query: 102 EQLLQLCAGGEPKALEHSTLD--NKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFES 159
++ L L E AL+ D +++F ++ ++ ++ E L + + ++ E
Sbjct: 203 KEELGLILE-EKCALQRQLEDLVEELSFSREQIQRARQTIAEQ-ESKLNEAHKSLSTVED 260
Query: 160 LMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNAN---ETM 216
L ++ S +++K AE K L+ L KE N ++D + ++ E +
Sbjct: 261 LKAEIVSASESRKELELKH-EAEVTNYKIKLEMLE----KEKNAVLDRMAESQEAELERL 315
Query: 217 ALQL---RTKELSCALSDLNTQ---NAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXX 270
QL +ELS DL + N E K + G H++ +
Sbjct: 316 RTQLLFSHEEELSKLKEDLEIEHRINIEKLKD-NLGIHYKQQID-----GLQNEMSQKIE 369
Query: 271 XXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQ 330
KD L ++QL + ++ L+ +L ++SE +L+ E
Sbjct: 370 TMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKG 429
Query: 331 ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMK--HEMNLN 388
L + Q ++ T LE +E K+++DM H
Sbjct: 430 TLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQ 489
Query: 389 IAKLI---EIEKKYNDSIEEK--KTLQENIDDLRTDLLESELRVKDLVRELDEKESILET 443
+LI I+ K DS+ EK + L E +DL+ ++ ++ E E
Sbjct: 490 EERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEV 549
Query: 444 K-QCVQKE---LESTKTDLEHRKTEIE-EYKRLLFEKGEEI 479
Q +Q+E L K DLE K + E EYK L EE+
Sbjct: 550 NYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEEL 590
Score = 33.1 bits (72), Expect = 3.5
Identities = 35/199 (17%), Positives = 81/199 (40%), Gaps = 14/199 (7%)
Query: 340 KDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKY 399
++ +E + EKLQ + S ++ +KH++++ IA+ + +E++
Sbjct: 2031 RNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQV 2090
Query: 400 NDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELE-STKTDL 458
++ E+ T +N+ L E+ ++ L +EL + E+ + +Q E S +
Sbjct: 2091 -ETANEEMTFMKNV------LKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVNVAI 2143
Query: 459 EHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXX 518
+H + E + +L E D LKS L + K
Sbjct: 2144 DHLSKDKPELEVVLTE-----DALKS-LENQTYFKSFEENGKGSIINLETRLLQLESTVS 2197
Query: 519 XRESQMKSYYEELMNLKNQ 537
++ ++ Y+++ +++ Q
Sbjct: 2198 AKDLELTQCYKQIKDMQEQ 2216
>X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein.
Length = 3259
Score = 54.8 bits (126), Expect = 1e-06
Identities = 97/539 (17%), Positives = 218/539 (40%), Gaps = 41/539 (7%)
Query: 130 NKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAE--NDLLK 187
N+LL + KC L + K+ + ++ + E K KI+ E N
Sbjct: 1951 NELLESEMKNLKKCVSELEEEKQQLVKEKTKVESE---IRKEYLEKIQGAQKEPGNKSHA 2007
Query: 188 SSLDQLRTEFLKEINDII-DCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSG 246
L +L E +E+ + DC+R + AL+ K L ++ ++ +
Sbjct: 2008 KELQELLKEKQQEVKQLQKDCIRYQ-EKISALERTVKALEFVQTESQKDLEITKENLAQA 2066
Query: 247 DHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSE 306
HR A ++ D L + + +L++N E V Q + +
Sbjct: 2067 VEHRKKAQAELASFKVLLDDTQSEAARVLADNL-KLKKELQSNKESVKS------QMKQK 2119
Query: 307 SWSLERTVXXXXXXXXXXXEDFDQELNKLTQS---IKDNTTHLEDIALAREKLQSXXXXX 363
LER + ++ ++L+ L + +++ ++ ++K
Sbjct: 2120 DEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQEN 2179
Query: 364 XXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSI----EEKKTLQENIDDLRTD 419
A++ KS+ ++ + + I + + E+K++D+I EE + ++N L+
Sbjct: 2180 LDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQ 2239
Query: 420 LLESELRVKDL---VRELDEKESILETK-----QCVQKELESTKTDLEHRKTEIEEYKRL 471
L + + +++L + L+ + I E+K Q QK ++ + + + +++EE + L
Sbjct: 2240 LRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHL 2299
Query: 472 LFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEEL 531
E+ +L+S+L K++KD +E+ +++
Sbjct: 2300 YHSSQNELAKLESEL---KSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSY 2356
Query: 532 MNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVE- 590
L+ + RE + + IN + K+ L +E E +Q E+++ +
Sbjct: 2357 EQLETDLQASREL-----TSRLHEEINMKEQKIISLLSGKE---EAIQVAIAELRQQHDK 2408
Query: 591 SMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLT 649
+ E E++L+++E+E +L E+ ++ ++ N L L+ + +I L + KS++
Sbjct: 2409 EIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMS 2467
Score = 52.4 bits (120), Expect = 5e-06
Identities = 134/674 (19%), Positives = 273/674 (40%), Gaps = 73/674 (10%)
Query: 2 KQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQ 61
+ +EL Q +T + NE + SE + LK + + EK K++ + +
Sbjct: 2285 ENKELLSQLEETRHLYHSSQNELAKLESE---LKSLKDQLTDLSNSLEKCKEQKGNLEGI 2341
Query: 62 VMELYASLRNTHRKMKLLGQKVNLPSAEEL--HIMNVAKLSPEQLLQLCAGGEPKALEHS 119
+ + A ++N+ + L + +L ++ EL + + ++++ L +G E +A++ +
Sbjct: 2342 IRQQEADIQNSKFSYEQL--ETDLQASRELTSRLHEEINMKEQKIISLLSGKE-EAIQVA 2398
Query: 120 TLDNKVTFDVNKLLNIPNSLVDKCEETLF---KRKEIINWFESLMSQEKGISTKTLTMK- 175
+ + D ++ + N L + EE + + K+ ++ LM K I + + K
Sbjct: 2399 IAELRQQHD-KEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKA 2457
Query: 176 -----IKEFNA---ENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSC 227
+K ++ + D + QL L I + +++ A E L+ + L
Sbjct: 2458 QLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRS 2517
Query: 228 ALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLK 287
+ DLN++NA++ ++ +R N+ S K L E QL+
Sbjct: 2518 HMDDLNSENAKLDAEL---IQYREDLNQ-----------VITIKDSQQKQLL---EVQLQ 2560
Query: 288 TNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNT---T 344
N E + A LE+ ES + +D +E+ L SI T T
Sbjct: 2561 QNKE-LENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVT 2619
Query: 345 HLED---IALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEM---NLNIAKLI-EIEK 397
L++ + L +L+ S+S K I +++ E+ AK + EIE
Sbjct: 2620 ALQEEGTLGLYHAQLKVKEEEVHRLSALFSSS-QKRIAELEEELVCVQKEAAKKVGEIED 2678
Query: 398 KYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKES--ILETK---------QC 446
K +E K L + +R + +E RV +L R+L E E ++ TK Q
Sbjct: 2679 KLK---KELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQS 2735
Query: 447 VQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXX 506
+ + S + +H E++E KR +E+ +LK + ++
Sbjct: 2736 FGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLN---RERDALLSETAFSM 2792
Query: 507 XXXXXXXXXXXXXRESQMKSYYEELMNLKNQI----TQLREFG-AFDNLNDVGNMINQQR 561
Q+ S E+L++L +Q+ Q++ F A +L + + + +
Sbjct: 2793 NSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNEL 2852
Query: 562 DKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIIN 621
+K + + ++ + T E++ L ++M+ ++ ++ KE+K L ++ + I
Sbjct: 2853 EKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEIT 2912
Query: 622 LLHN-KLELRNEAD 634
LH K +L+ D
Sbjct: 2913 ELHPLKAQLQEYQD 2926
Score = 44.4 bits (100), Expect = 0.001
Identities = 100/575 (17%), Positives = 217/575 (37%), Gaps = 38/575 (6%)
Query: 49 EKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLC 108
E+ + +E + + ELY LR+T K +++ + +E+ M E++ +
Sbjct: 1630 ERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQ-EAEQEMEEMK------EKMRKFA 1682
Query: 109 AGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGIS 168
+ K LE ++++ +V+ +C ETL + E L + +
Sbjct: 1683 KSKQQKILELEEENDRLRAEVHPA----GDTAKECMETLLSSNASMK--EEL--ERVKME 1734
Query: 169 TKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDI--IDCLRKNANETMALQLRTKELS 226
+TL+ K + +E D L + L+ + ++ ++ K+ N+T + T+ +
Sbjct: 1735 YETLSKKFQSLMSEKDSLSEEVQDLKHQIEDNVSKQANLEATEKHDNQTNVTEEGTQSIP 1794
Query: 227 CALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSI--MKDRLSRAEH 284
+ ++ + R AN I +K+R++ E
Sbjct: 1795 GETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEE 1854
Query: 285 QLKTNVERVVQLE----AALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIK 340
+ + N E LE L Q ++ L + + + +EL+++T+ +K
Sbjct: 1855 EKQKNKEFSQTLENEKNTLLSQISTKDGEL-KMLQEEVTKMNLLNQQIQEELSRVTK-LK 1912
Query: 341 DNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNL-NIAKLI-EIEKK 398
+ +D L + + IK+ E + N+ K + E+E++
Sbjct: 1913 ETAEEEKD-DLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEE 1971
Query: 399 YNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDL 458
++EK ++ I + ++ + E + +L+ KQ K+L+
Sbjct: 1972 KQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRY 2031
Query: 459 EHRKTEIEE-YKRLLFEKGEEIDELK-SKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXX 516
+ + + +E K L F + E +L+ +K + +A++
Sbjct: 2032 QEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEA 2091
Query: 517 XXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDE 576
+K E N ++ +Q+++ D+ + Q +K K ++ E
Sbjct: 2092 ARVLADNLKLKKELQSNKESVKSQMKQKD-----EDLERRLEQAEEKHL---KEKKNMQE 2143
Query: 577 KLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNE 611
KL E L E++ E + LNKK+KE++ L E
Sbjct: 2144 KLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQE 2178
Score = 43.2 bits (97), Expect = 0.003
Identities = 132/674 (19%), Positives = 256/674 (37%), Gaps = 74/674 (10%)
Query: 5 ELEIQQNQTDGCLYEDLNE----QESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQN 60
ELE++ + T L + E QE I + +I LKTV E V E +++LE Q
Sbjct: 1320 ELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQL 1379
Query: 61 QVMELYASLRNTHRKM----KLLGQK---VNLPSAE------ELHIMNVAKLSPEQLLQ- 106
Q+ L LR K+ KL+ +K V+ S + L + + E L++
Sbjct: 1380 QIAGL-EHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKA 1438
Query: 107 LCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVD----------KCEETLFKRKEIINW 156
L E +A EH ++ ++ ++ P + + K + L RKE +
Sbjct: 1439 LHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKE 1498
Query: 157 FESL---MSQEKGISTKTLTMKIKEFNAENDLLKSSLDQL--RTEFLKEIND-IIDCLRK 210
+SL +S +G + + LT + + ++ D + R L+E D +I + +
Sbjct: 1499 NKSLQEELSLARG-TIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDR 1557
Query: 211 NANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXX 270
+ E +L + L AL L ++ K+I S ++
Sbjct: 1558 SLLENQSLSSSCESLKLALEGLTEDKEKLVKEIES--------LKSSKIAESTEWQEKHK 1609
Query: 271 XXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQ 330
+ L ++ + ER+ + A+ Q + E + R+ ++ +Q
Sbjct: 1610 ELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQ 1669
Query: 331 ELNKLTQSI----KDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMN 386
E+ ++ + + K + ++ ++L++ + S MK E+
Sbjct: 1670 EMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELE 1729
Query: 387 LNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQC 446
+ + KK+ + EK +L E + DL+ +++D V K++ LE +
Sbjct: 1730 RVKMEYETLSKKFQSLMSEKDSLSEEVQDLKH-------QIEDNV----SKQANLEATEK 1778
Query: 447 VQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE-LKSKLSTEKAI-KDIXXXXXXXXX 504
+ T+ + E EE L E + S S A+ KD
Sbjct: 1779 HDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNY 1838
Query: 505 XXXXXXXXXXXXXXXRESQM-KSYYEELMNLKNQI-----TQLREFGAFDNLNDVGNMIN 558
E Q K + + L N KN + T+ E N++N
Sbjct: 1839 LQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLN 1898
Query: 559 QQ-RDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEI---KMLNEKEE 614
QQ +++L +TK +E +E+ K++ +RL+ + E + +++ ++ NE E
Sbjct: 1899 QQIQEELSRVTKLKETAEEE---KDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLE 1955
Query: 615 EHMNIINLLHNKLE 628
M + ++LE
Sbjct: 1956 SEMKNLKKCVSELE 1969
Score = 41.1 bits (92), Expect = 0.013
Identities = 47/242 (19%), Positives = 102/242 (42%), Gaps = 11/242 (4%)
Query: 396 EKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTK 455
E + + E + + +++L L + EL + + + L EK+ +ET Q +E +
Sbjct: 844 ESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQV 903
Query: 456 TDLEHRKTE-IEEYKRLLFEKGEEIDELKSKLS----TEKAIKDIXXXXXXXXXXXXXXX 510
T++ TE + + F G EI LK +L+ E+A K+
Sbjct: 904 TEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNY 963
Query: 511 XXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKR 570
+ +++ + +L+ +N+ + + A N ++ +++ ++L L
Sbjct: 964 DEMSPAGQISKEELQHEF-DLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDE 1022
Query: 571 QEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM-----LNEKEEEHMNIINLLHN 625
++ +T+ E++ E+ E + K +EI++ ++EKE E +I L
Sbjct: 1023 SKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEE 1082
Query: 626 KL 627
KL
Sbjct: 1083 KL 1084
Score = 40.3 bits (90), Expect = 0.023
Identities = 60/292 (20%), Positives = 126/292 (43%), Gaps = 23/292 (7%)
Query: 376 KSIKDMKHEMNLNIAKL---IEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVR 432
+S+K + HE ++ L +E + +E + LQ +D+L+ + + E V L
Sbjct: 1354 ESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSG 1413
Query: 433 ELDEKESIL---ETKQCVQKEL-ESTKTDLEHRKTEIEE-YKRL---LFEKGEEIDELKS 484
+L EKE+ L +T+ Q++L ++ T LE + E +E K+L L E ++ +E+
Sbjct: 1414 QLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGE 1473
Query: 485 KLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREF 544
+ ++ I+ ++ + L ++++Q++ +
Sbjct: 1474 ESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNK- 1532
Query: 545 GAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNK--- 601
D + ++ ++RDKL R ++ L + +K +E +TE + L K
Sbjct: 1533 -EKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIE 1591
Query: 602 --KEKEIKMLNEKEEEHMNIIN----LLHNKLELRNEAD-IDVIITLAKYKK 646
K +I E +E+H + LL + + NEA+ I ++ + +K
Sbjct: 1592 SLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEK 1643
Score = 39.5 bits (88), Expect = 0.040
Identities = 53/268 (19%), Positives = 108/268 (40%), Gaps = 9/268 (3%)
Query: 378 IKDMKHEMNLNIAKLIEI-EKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDE 436
+K E+ LN K EI EK ++ +E L + I++ + + + L E D+
Sbjct: 689 LKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQ 748
Query: 437 KESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSK----LSTEKAI 492
S ++ V EL + LE E E +RL +E D L ++ LS E
Sbjct: 749 LLSQVKELSMVT-ELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKS 807
Query: 493 KDIXXXXXXXXXXXXXXXXXXXXXXXXR-ESQMKSYYEELMNLKNQITQL--REFGAFDN 549
KD+ +SQ+++ E++ ++ + +
Sbjct: 808 KDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQA 867
Query: 550 LNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKML 609
L+ I + L E + E + ++ K+ ++ + SMTE+ LN+++ + +
Sbjct: 868 LSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVE 927
Query: 610 NEKEEEHMNIINLLHNKLELRNEADIDV 637
+ +E +N+++ + + E D +V
Sbjct: 928 IKTLKEQLNLLSRAEEAKKEQVEEDNEV 955
Score = 35.5 bits (78), Expect = 0.65
Identities = 41/246 (16%), Positives = 100/246 (40%), Gaps = 23/246 (9%)
Query: 388 NIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD-----EKESILE 442
N+ ++ E +E T QE++ + + + +KD++R+ D + E++ E
Sbjct: 25 NMRAPLDPELHQESDMEFNNTTQEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQE 84
Query: 443 TKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI--------DEL----KSKLSTEK 490
++ +++ K + + T + +Y + +G + ++L KS E
Sbjct: 85 ERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEPQSEEQLSKHDKSSTEEEM 144
Query: 491 AIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNL 550
I+ I + +Q + EE + +K Q+ + EF L
Sbjct: 145 EIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEF--ISTL 202
Query: 551 NDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLN 610
+ ++ + ++ ++ +++ E+E+ +LV Q V + ++++++L
Sbjct: 203 QAQLSQTQAEQAAQQVVREKDARFETQVRLHEDELLQLV----TQADVETEMQQKLRVLQ 258
Query: 611 EKEEEH 616
K EEH
Sbjct: 259 RKLEEH 264
>D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372 protein.
Length = 3225
Score = 54.8 bits (126), Expect = 1e-06
Identities = 97/539 (17%), Positives = 218/539 (40%), Gaps = 41/539 (7%)
Query: 130 NKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAE--NDLLK 187
N+LL + KC L + K+ + ++ + E K KI+ E N
Sbjct: 1917 NELLESEMKNLKKCVSELEEEKQQLVKEKTKVESE---IRKEYLEKIQGAQKEPGNKSHA 1973
Query: 188 SSLDQLRTEFLKEINDII-DCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSG 246
L +L E +E+ + DC+R + AL+ K L ++ ++ +
Sbjct: 1974 KELQELLKEKQQEVKQLQKDCIRYQ-EKISALERTVKALEFVQTESQKDLEITKENLAQA 2032
Query: 247 DHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSE 306
HR A ++ D L + + +L++N E V Q + +
Sbjct: 2033 VEHRKKAQAELASFKVLLDDTQSEAARVLADNL-KLKKELQSNKESVKS------QMKQK 2085
Query: 307 SWSLERTVXXXXXXXXXXXEDFDQELNKLTQS---IKDNTTHLEDIALAREKLQSXXXXX 363
LER + ++ ++L+ L + +++ ++ ++K
Sbjct: 2086 DEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQEN 2145
Query: 364 XXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSI----EEKKTLQENIDDLRTD 419
A++ KS+ ++ + + I + + E+K++D+I EE + ++N L+
Sbjct: 2146 LDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQ 2205
Query: 420 LLESELRVKDL---VRELDEKESILETK-----QCVQKELESTKTDLEHRKTEIEEYKRL 471
L + + +++L + L+ + I E+K Q QK ++ + + + +++EE + L
Sbjct: 2206 LRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHL 2265
Query: 472 LFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEEL 531
E+ +L+S+L K++KD +E+ +++
Sbjct: 2266 YHSSQNELAKLESEL---KSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSY 2322
Query: 532 MNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVE- 590
L+ + RE + + IN + K+ L +E E +Q E+++ +
Sbjct: 2323 EQLETDLQASREL-----TSRLHEEINMKEQKIISLLSGKE---EAIQVAIAELRQQHDK 2374
Query: 591 SMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLT 649
+ E E++L+++E+E +L E+ ++ ++ N L L+ + +I L + KS++
Sbjct: 2375 EIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMS 2433
Score = 52.4 bits (120), Expect = 5e-06
Identities = 134/674 (19%), Positives = 273/674 (40%), Gaps = 73/674 (10%)
Query: 2 KQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQ 61
+ +EL Q +T + NE + SE + LK + + EK K++ + +
Sbjct: 2251 ENKELLSQLEETRHLYHSSQNELAKLESE---LKSLKDQLTDLSNSLEKCKEQKGNLEGI 2307
Query: 62 VMELYASLRNTHRKMKLLGQKVNLPSAEEL--HIMNVAKLSPEQLLQLCAGGEPKALEHS 119
+ + A ++N+ + L + +L ++ EL + + ++++ L +G E +A++ +
Sbjct: 2308 IRQQEADIQNSKFSYEQL--ETDLQASRELTSRLHEEINMKEQKIISLLSGKE-EAIQVA 2364
Query: 120 TLDNKVTFDVNKLLNIPNSLVDKCEETLF---KRKEIINWFESLMSQEKGISTKTLTMK- 175
+ + D ++ + N L + EE + + K+ ++ LM K I + + K
Sbjct: 2365 IAELRQQHD-KEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKA 2423
Query: 176 -----IKEFNA---ENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSC 227
+K ++ + D + QL L I + +++ A E L+ + L
Sbjct: 2424 QLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRS 2483
Query: 228 ALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLK 287
+ DLN++NA++ ++ +R N+ S K L E QL+
Sbjct: 2484 HMDDLNSENAKLDAEL---IQYREDLNQ-----------VITIKDSQQKQLL---EVQLQ 2526
Query: 288 TNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNT---T 344
N E + A LE+ ES + +D +E+ L SI T T
Sbjct: 2527 QNKE-LENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVT 2585
Query: 345 HLED---IALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEM---NLNIAKLI-EIEK 397
L++ + L +L+ S+S K I +++ E+ AK + EIE
Sbjct: 2586 ALQEEGTLGLYHAQLKVKEEEVHRLSALFSSS-QKRIAELEEELVCVQKEAAKKVGEIED 2644
Query: 398 KYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKES--ILETK---------QC 446
K +E K L + +R + +E RV +L R+L E E ++ TK Q
Sbjct: 2645 KLK---KELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQS 2701
Query: 447 VQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXX 506
+ + S + +H E++E KR +E+ +LK + ++
Sbjct: 2702 FGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLN---RERDALLSETAFSM 2758
Query: 507 XXXXXXXXXXXXXRESQMKSYYEELMNLKNQI----TQLREFG-AFDNLNDVGNMINQQR 561
Q+ S E+L++L +Q+ Q++ F A +L + + + +
Sbjct: 2759 NSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNEL 2818
Query: 562 DKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIIN 621
+K + + ++ + T E++ L ++M+ ++ ++ KE+K L ++ + I
Sbjct: 2819 EKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEIT 2878
Query: 622 LLHN-KLELRNEAD 634
LH K +L+ D
Sbjct: 2879 ELHPLKAQLQEYQD 2892
Score = 44.0 bits (99), Expect = 0.002
Identities = 100/575 (17%), Positives = 217/575 (37%), Gaps = 38/575 (6%)
Query: 49 EKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLC 108
E+ + +E + + ELY LR+T K +++ + +E+ M E++ +
Sbjct: 1596 ERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQ-EAEQEMEEMK------EKMRKFA 1648
Query: 109 AGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGIS 168
+ K LE ++++ +V+ +C ETL + E L + +
Sbjct: 1649 KSKQQKILELEEENDRLRAEVHPA----GDTAKECMETLLSSNASMK--EEL--ERVKME 1700
Query: 169 TKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDI--IDCLRKNANETMALQLRTKELS 226
+TL+ K + +E D L + L+ + ++ ++ K+ N+T + T+ +
Sbjct: 1701 YETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIP 1760
Query: 227 CALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSI--MKDRLSRAEH 284
+ ++ + R AN I +K+R++ E
Sbjct: 1761 GETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEE 1820
Query: 285 QLKTNVERVVQLE----AALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIK 340
+ + N E LE L Q ++ L + + + +EL+++T+ +K
Sbjct: 1821 EKQKNKEFSQTLENEKNTLLSQISTKDGEL-KMLQEEVTKMNLLNQQIQEELSRVTK-LK 1878
Query: 341 DNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNL-NIAKLI-EIEKK 398
+ +D L + + IK+ E + N+ K + E+E++
Sbjct: 1879 ETAEEEKD-DLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEE 1937
Query: 399 YNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDL 458
++EK ++ I + ++ + E + +L+ KQ K+L+
Sbjct: 1938 KQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRY 1997
Query: 459 EHRKTEIEE-YKRLLFEKGEEIDELK-SKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXX 516
+ + + +E K L F + E +L+ +K + +A++
Sbjct: 1998 QEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEA 2057
Query: 517 XXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDE 576
+K E N ++ +Q+++ D+ + Q +K K ++ E
Sbjct: 2058 ARVLADNLKLKKELQSNKESVKSQMKQKD-----EDLERRLEQAEEKHL---KEKKNMQE 2109
Query: 577 KLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNE 611
KL E L E++ E + LNKK+KE++ L E
Sbjct: 2110 KLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQE 2144
Score = 41.5 bits (93), Expect = 0.010
Identities = 131/674 (19%), Positives = 254/674 (37%), Gaps = 74/674 (10%)
Query: 5 ELEIQQNQTDGCLYEDLNE----QESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQN 60
ELE++ + T L + E QE I + +I LKTV E V E +++LE Q
Sbjct: 1286 ELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQL 1345
Query: 61 QVMELYASLRNTHRKM----KLLGQK---VNLPSAE------ELHIMNVAKLSPEQLLQ- 106
Q+ L LR K+ KL+ +K V+ S + L + + E L++
Sbjct: 1346 QIAGL-EHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKA 1404
Query: 107 LCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVD----------KCEETLFKRKEIINW 156
L E +A EH ++ ++ ++ P + + K + L RKE +
Sbjct: 1405 LHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKE 1464
Query: 157 FESL---MSQEKGISTKTLTMKIKEFNAENDLLKSSLDQL--RTEFLKEIND-IIDCLRK 210
+SL +S +G + + LT + + ++ D + R L+E D +I + +
Sbjct: 1465 NKSLQEELSLARG-TIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDR 1523
Query: 211 NANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXX 270
+ E +L + L AL L ++ K+I S ++
Sbjct: 1524 SLLENQSLSSSCESLKLALEGLTEDKEKLVKEIES--------LKSSKIAESTEWQEKHK 1575
Query: 271 XXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQ 330
+ L ++ + ER+ + A+ Q + E + R+ ++ +Q
Sbjct: 1576 ELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQ 1635
Query: 331 ELNKLTQSI----KDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMN 386
E+ ++ + + K + ++ ++L++ + S MK E+
Sbjct: 1636 EMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELE 1695
Query: 387 LNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQC 446
+ + KK+ + EK +L E + DL+ +E + K++ LE +
Sbjct: 1696 RVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQ-IEGNV----------SKQANLEATEK 1744
Query: 447 VQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE-LKSKLSTEKAI-KDIXXXXXXXXX 504
+ T+ + E EE L E + S S A+ KD
Sbjct: 1745 HDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNY 1804
Query: 505 XXXXXXXXXXXXXXXRESQM-KSYYEELMNLKNQI-----TQLREFGAFDNLNDVGNMIN 558
E Q K + + L N KN + T+ E N++N
Sbjct: 1805 LQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLN 1864
Query: 559 QQ-RDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEI---KMLNEKEE 614
QQ +++L +TK +E +E+ K++ +RL+ + E + +++ ++ NE E
Sbjct: 1865 QQIQEELSRVTKLKETAEEE---KDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLE 1921
Query: 615 EHMNIINLLHNKLE 628
M + ++LE
Sbjct: 1922 SEMKNLKKCVSELE 1935
Score = 41.1 bits (92), Expect = 0.013
Identities = 47/242 (19%), Positives = 102/242 (42%), Gaps = 11/242 (4%)
Query: 396 EKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTK 455
E + + E + + +++L L + EL + + + L EK+ +ET Q +E +
Sbjct: 810 ESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQV 869
Query: 456 TDLEHRKTE-IEEYKRLLFEKGEEIDELKSKLS----TEKAIKDIXXXXXXXXXXXXXXX 510
T++ TE + + F G EI LK +L+ E+A K+
Sbjct: 870 TEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNY 929
Query: 511 XXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKR 570
+ +++ + +L+ +N+ + + A N ++ +++ ++L L
Sbjct: 930 DEMSPAGQISKEELQHEF-DLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDE 988
Query: 571 QEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM-----LNEKEEEHMNIINLLHN 625
++ +T+ E++ E+ E + K +EI++ ++EKE E +I L
Sbjct: 989 SKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEE 1048
Query: 626 KL 627
KL
Sbjct: 1049 KL 1050
Score = 40.3 bits (90), Expect = 0.023
Identities = 60/292 (20%), Positives = 126/292 (43%), Gaps = 23/292 (7%)
Query: 376 KSIKDMKHEMNLNIAKL---IEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVR 432
+S+K + HE ++ L +E + +E + LQ +D+L+ + + E V L
Sbjct: 1320 ESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSG 1379
Query: 433 ELDEKESIL---ETKQCVQKEL-ESTKTDLEHRKTEIEE-YKRL---LFEKGEEIDELKS 484
+L EKE+ L +T+ Q++L ++ T LE + E +E K+L L E ++ +E+
Sbjct: 1380 QLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGE 1439
Query: 485 KLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREF 544
+ ++ I+ ++ + L ++++Q++ +
Sbjct: 1440 ESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNK- 1498
Query: 545 GAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNK--- 601
D + ++ ++RDKL R ++ L + +K +E +TE + L K
Sbjct: 1499 -EKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIE 1557
Query: 602 --KEKEIKMLNEKEEEHMNIIN----LLHNKLELRNEAD-IDVIITLAKYKK 646
K +I E +E+H + LL + + NEA+ I ++ + +K
Sbjct: 1558 SLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEK 1609
Score = 39.5 bits (88), Expect = 0.040
Identities = 53/268 (19%), Positives = 108/268 (40%), Gaps = 9/268 (3%)
Query: 378 IKDMKHEMNLNIAKLIEI-EKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDE 436
+K E+ LN K EI EK ++ +E L + I++ + + + L E D+
Sbjct: 655 LKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQ 714
Query: 437 KESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSK----LSTEKAI 492
S ++ V EL + LE E E +RL +E D L ++ LS E
Sbjct: 715 LLSQVKELSMVT-ELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKS 773
Query: 493 KDIXXXXXXXXXXXXXXXXXXXXXXXXR-ESQMKSYYEELMNLKNQITQL--REFGAFDN 549
KD+ +SQ+++ E++ ++ + +
Sbjct: 774 KDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQA 833
Query: 550 LNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKML 609
L+ I + L E + E + ++ K+ ++ + SMTE+ LN+++ + +
Sbjct: 834 LSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVE 893
Query: 610 NEKEEEHMNIINLLHNKLELRNEADIDV 637
+ +E +N+++ + + E D +V
Sbjct: 894 IKTLKEQLNLLSRAEEAKKEQVEEDNEV 921
>BC127816-1|AAI27817.1| 416|Homo sapiens Unknown (protein for
IMAGE:40131779) protein.
Length = 416
Score = 54.8 bits (126), Expect = 1e-06
Identities = 49/240 (20%), Positives = 110/240 (45%), Gaps = 10/240 (4%)
Query: 400 NDSIEEKKT-LQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQ-----KELES 453
++ ++EK LQE + + ++ E +L VK+L R+L+ + +L + + KEL+S
Sbjct: 174 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQLQAEADHLGKELQS 233
Query: 454 TKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLST-EKAIKDIXXXXXXXXXXXXXXXXX 512
L+ + E E + RL ++ E++ + K+ E+ I++
Sbjct: 234 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE-QEEKIREQEEKIREQEE 292
Query: 513 XXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQE 572
+ + + +E ++ Q ++RE + + + I +Q +K++E ++
Sbjct: 293 MMQEQEEKMGEQEEKMQEQEKMRRQEEKIRE--QEEKIREQKEKIREQEEKIWEQEEKIR 350
Query: 573 EYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNE 632
E +E +Q +E ++ E M EQE + ++E++++ EK E + K++ E
Sbjct: 351 EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 410
>AB053469-1|BAC54108.1| 720|Homo sapiens ELKS gamma protein.
Length = 720
Score = 54.8 bits (126), Expect = 1e-06
Identities = 52/258 (20%), Positives = 114/258 (44%), Gaps = 23/258 (8%)
Query: 376 KSIKDMKH-EMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVREL 434
K + D+K ++N+ K+ ++++ D ++ +L+E + L+ D ++ + L L
Sbjct: 263 KDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEAL 322
Query: 435 DEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA-IK 493
EKE +E + E D ++ EI+ YK+ L + E++ L+ LS ++A +
Sbjct: 323 AEKERTIERLK------EQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLL 376
Query: 494 DIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDV 553
D+ E ++ EE + +++Q+ + E A +
Sbjct: 377 DLKEHASSLASSGLKKDSRLKTL----EIALEQKKEECLKMESQLKKAHE-AALE----- 426
Query: 554 GNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKML---- 609
+ D++ L + Y ++ + E+ RL+E + E E+ N K+K+I L
Sbjct: 427 ARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELESLT 486
Query: 610 -NEKEEEHMNIINLLHNK 626
+ ++++ + NL H +
Sbjct: 487 SRQVKDQNKKVANLKHKE 504
Score = 49.6 bits (113), Expect = 4e-05
Identities = 103/480 (21%), Positives = 201/480 (41%), Gaps = 54/480 (11%)
Query: 17 LYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKM 76
L +D+ +ES S S + +KT W ++ KKE R+++ AS ++
Sbjct: 168 LRKDVEVKESKLSSS--MNSIKTFWSPEL------KKERALRKDE-----ASKITIWKEQ 214
Query: 77 KLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTL-DNKVTFDVN-KLLN 134
+ Q+ N A L + + ++ Q+ E K + + D K DV + +N
Sbjct: 215 YRVVQEENQVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVN 274
Query: 135 IPNSLVDKCEETLF-KRKEIINWFESLMS-QEKGISTKTLTMKIKEFNAENDLLKSSLDQ 192
+ ++ +E L K K++ + E + S Q +T T ++E AE + L +
Sbjct: 275 VLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKE 334
Query: 193 LRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPY 252
R +E + ID +K+ + L+ K +S DL+ + A + + +H
Sbjct: 335 QRDRDEREKQEEIDNYKKDLKD-----LKEK-VSLLQGDLSEKEASL---LDLKEHASSL 385
Query: 253 ANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLER 312
A+ K+ + E QLK E ++ A+ E + LER
Sbjct: 386 ASSGLKKDSRLKTLEIALEQK--KEECLKMESQLKKAHEAALEARASPEMS-DRIQHLER 442
Query: 313 TVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSA 372
+ + D+ L L + +N + +D +A +L+S
Sbjct: 443 EITRYKDESSKAQAEVDRLLEILKEV--ENEKNDKDKKIA--ELESLTSRQVK------- 491
Query: 373 SYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVR 432
NK + ++KH+ + +KK +EE + ++N++D L +S + D +
Sbjct: 492 DQNKKVANLKHKEQVE-------KKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIE 544
Query: 433 ELDE--KESILET--KQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLST 488
EL+E +ES+ T ++ V + ES +T+ E ++EE + + +E++ +K+KLS+
Sbjct: 545 ELEEALRESVQITAEREMVLAQEESARTNAE---KQVEELLMAMEKVKQELESMKAKLSS 601
Score = 35.1 bits (77), Expect = 0.86
Identities = 21/79 (26%), Positives = 49/79 (62%), Gaps = 3/79 (3%)
Query: 560 QRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNI 619
++D+ ++T +E+Y ++ +EN++ L + E+E +LNKK K+I+ + E++
Sbjct: 201 RKDEASKITIWKEQY--RVVQEENQVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGE 258
Query: 620 INLLHNKLELRNEADIDVI 638
I+ L + L+++ E ++V+
Sbjct: 259 IHDLKDMLDVK-ERKVNVL 276
Score = 34.7 bits (76), Expect = 1.1
Identities = 25/101 (24%), Positives = 47/101 (46%), Gaps = 4/101 (3%)
Query: 397 KKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQ----CVQKELE 452
K+ D EEK T I DL+ L E +V L ++++ + L K+ +++ ++
Sbjct: 243 KQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVK 302
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIK 493
S + D + T + + L EK I+ LK + ++ K
Sbjct: 303 SLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREK 343
>AL139421-1|CAI22508.1| 1454|Homo sapiens coiled-coil domain
containing 18 protein.
Length = 1454
Score = 54.4 bits (125), Expect = 1e-06
Identities = 99/622 (15%), Positives = 250/622 (40%), Gaps = 36/622 (5%)
Query: 24 QESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKV 83
+ +T + ++ L+ +EK+V + + + + ++ME +R+ + +K+
Sbjct: 570 ESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKI 629
Query: 84 NL--PSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSL-- 139
L A+++H+ ++ +Q+ +L A E K + + ++ ++ + L
Sbjct: 630 CLAFEKAKKIHLEQHKEME-KQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLES 688
Query: 140 VDK--CEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEF 197
+D+ E +KE + E+L + + +S +T+ K+++ ++ ++ K L +
Sbjct: 689 LDRLLTESKGEMKKENMKKDEALKALQNQVSEETI--KVRQLDSALEICKEELVLHLNQL 746
Query: 198 LKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNX 257
L+K + E LQ K + +L + + QN ++ H+ + +
Sbjct: 747 EGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQ---HTLQQQQQMLQQET 803
Query: 258 XXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXX 317
+ K + Q +++ E++ ++E E A E+ + V
Sbjct: 804 IRNGELEDTQTKLEKQVSKLE-QELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIEL 862
Query: 318 XXXXXXXXEDFDQ---ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASY 374
+ DQ EL+K+ + I E+ A+ +L + +
Sbjct: 863 TGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAV 922
Query: 375 NKSIKDMKHEMNLNIAKLIE----IEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDL 430
K ++ ++H + + ++ +E + ++ E K+ + +LR L +++L
Sbjct: 923 -KELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQL----- 976
Query: 431 VRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS-TE 489
L+EK + ++ + EL K ++E +K E+ E + L E+ E+ + ++++ +
Sbjct: 977 --SLEEKYTTIKD---LTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLD 1031
Query: 490 KAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDN 549
I++ Q++S ++L N K Q+ + +EF N
Sbjct: 1032 MTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLRE-KEFIMLQN 1090
Query: 550 LNDVGNM---INQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEI 606
++ + I + + ++ E+ +E ++ + T+ E L + + + E+
Sbjct: 1091 EQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTEL 1150
Query: 607 KMLNEKEEEHMNIINLLHNKLE 628
++ + I L ++LE
Sbjct: 1151 AEARHQQVQAQREIERLSSELE 1172
Score = 47.2 bits (107), Expect = 2e-04
Identities = 85/509 (16%), Positives = 198/509 (38%), Gaps = 38/509 (7%)
Query: 172 LTMKIKEFNAENDLLK-------SSLDQLRTEFLKEIND---IIDCLRKNANETMALQLR 221
L K+ + AEN LK S ++ E L++ ++ + + K ++ + L+ +
Sbjct: 527 LRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQ 586
Query: 222 TKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSR 281
+E A S + +NAE+ +++ + N I ++
Sbjct: 587 LEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKE 646
Query: 282 AEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKD 341
E Q++ +LEA LE+ + E+T+ L L + + +
Sbjct: 647 MEKQIE-------RLEAQLEKKDQQFKEQEKTMSMLQQDIICK----QHHLESLDRLLTE 695
Query: 342 NTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLI----EIEK 397
+ ++ + +++ + +++ K E+ L++ +L + EK
Sbjct: 696 SKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEK 755
Query: 398 KYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTD 457
+ EE LQ+ + L E+ + L L +++ +L+ + ELE T+T
Sbjct: 756 QLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTK 815
Query: 458 LEHRKTEIE-EYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXX 516
LE + +++E E ++ E++ +++ K + D+
Sbjct: 816 LEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQV------ 869
Query: 517 XXXRESQMKSYYEELMNLKNQITQLREFGAFD--NLNDVGNMINQQRDKLFELTKRQEEY 574
+ +M Y EEL ++ +I L+ G +L+ + +++Q + +L + T +E
Sbjct: 870 ----KIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKEL 925
Query: 575 DEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEAD 634
++ + E E+ ++ E L E+K + +E +++ LE +
Sbjct: 926 EKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTI 985
Query: 635 IDVIITLAKYKKSLTLVLEKMSISNRVLK 663
D+ L + K + +++ ++ LK
Sbjct: 986 KDLTAELRECKMEIEDKKQELLEMDQALK 1014
Score = 42.3 bits (95), Expect = 0.006
Identities = 122/656 (18%), Positives = 259/656 (39%), Gaps = 59/656 (8%)
Query: 22 NEQESITSES-HKITKLKTVWQEKMVT-FEKSKKELEDRQNQVMELYASLRNTHRKMKLL 79
++ ES+ ++ H + K ++++VT E+ + +L + + +L ++ + + +L+
Sbjct: 496 HQVESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLI 555
Query: 80 GQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSL 139
+++ ++ + + QLL L E K + +S++ K ++ + L N
Sbjct: 556 QEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAK-NAELEQELMEKNEK 614
Query: 140 VDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLK 199
+ E + E I ++ EK + K + KE + + L++ L++ +F K
Sbjct: 615 IRSLETNINTEHEKI-----CLAFEK--AKKIHLEQHKEMEKQIERLEAQLEKKDQQF-K 666
Query: 200 EINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXX 259
E + L++ + + Q + L L++ EM+K+ D A +N
Sbjct: 667 EQEKTMSMLQQ---DIICKQHHLESLDRLLTE---SKGEMKKENMKKDEALK-ALQNQVS 719
Query: 260 XXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXX 319
I K+ L +QL+ N E+ E L++ E + L++ +
Sbjct: 720 EETIKVRQLDSALEICKEELVLHLNQLEGNKEK---FEKQLKKKSEEVYCLQKELKIKNH 776
Query: 320 XXXXXXED---FDQELNKLTQSIKDNTTH---LEDIALAREKLQSXXXXXXXXXXXXSAS 373
E L + Q ++ T LED EK S SA
Sbjct: 777 SLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAE 836
Query: 374 YNKSIKDM----KHEMNLNIAKLIE-------IEKKYNDSIEEKKTLQENIDDLRTDLLE 422
+ +++ HE +L K+IE ++ + + EE +++ I L+ D
Sbjct: 837 KLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGEN 896
Query: 423 SELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLL-FEKGEEIDE 481
+ + L LD+ ++ LE K KELE + E TE + + +L E E
Sbjct: 897 KAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGE 956
Query: 482 LKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMN----LKNQ 537
LKS L + ++D+ + +++ +EL+ LK +
Sbjct: 957 LKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKER 1016
Query: 538 ITQLREFGAFDNLNDV------GNM----------INQQRDKLFELTKRQEEYDEKLQTK 581
+L++ A D+ G M + + +L E K+ E ++KLQ
Sbjct: 1017 NWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNA 1076
Query: 582 ENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDV 637
+ +++ M + E +++ +KEI+ ++ +E +++ + + + ID+
Sbjct: 1077 KEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDL 1132
Score = 33.9 bits (74), Expect = 2.0
Identities = 64/336 (19%), Positives = 130/336 (38%), Gaps = 28/336 (8%)
Query: 275 MKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNK 334
M L +LK +V L+ + + R E +E+ + + +E NK
Sbjct: 1009 MDQALKERNWELKQRAAQVTHLDMTIREHRGE---MEQKIIKLEGTLEKSELEL-KECNK 1064
Query: 335 LTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIE 394
+S+ D + ++ +E + + +K+M+ M +
Sbjct: 1065 QIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIAT 1124
Query: 395 IEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELEST 454
K+ D +E + +E + + T+L E+ + RE++ S LE + + KE ++
Sbjct: 1125 QYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAH 1184
Query: 455 KTDLEHRKTEIEEYK-RLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXX 513
H E+ K R + E+K KLS E ++ +
Sbjct: 1185 G---NHLAEELGASKVREAHLEARMQAEIK-KLSAE--VESLKEAYHMEMISHQENHAKW 1238
Query: 514 XXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEE 573
++S ++ E+L K ++ + A D ++++ + Q R+++ E
Sbjct: 1239 KISADSQKSSVQQLNEQLEKAKLELEE-----AQDTVSNLHQQV-QDRNEVIEAA----- 1287
Query: 574 YDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKML 609
+E L TKE+E+ RL ++ E K ++IK L
Sbjct: 1288 -NEALLTKESELTRLQAKISGHE-----KAEDIKFL 1317
>U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-coil
containing protein kinase p160ROCK protein.
Length = 1354
Score = 54.0 bits (124), Expect = 2e-06
Identities = 127/660 (19%), Positives = 258/660 (39%), Gaps = 69/660 (10%)
Query: 11 NQTDGCLYEDLNEQ-ESITSESHKITKLKTVWQEKMVT----FEKSKKELEDRQNQVMEL 65
+ D L E L + + + H +LK ++K T +K KEL++ NQ L
Sbjct: 418 SNADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNL 477
Query: 66 YASLRNTHRKMKLLGQKVN-------LPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEH 118
+++ ++ LL ++N + + ++ N +QL L K ++
Sbjct: 478 ESTVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDL-----KKVSQN 532
Query: 119 STLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKE 178
S L N+ + K L N L+ +T + ++ +SQ + ++ +E
Sbjct: 533 SQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLN--------RE 584
Query: 179 FNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMA----LQLRTKELSCALSDL-- 232
N +L++S Q ++ ++ I++ R++ LQ R L + L
Sbjct: 585 LQERNRILENSKSQTDKDYY-QLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKH 643
Query: 233 NTQNAE-MRKQIHSGDHH--RPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRA----EHQ 285
N + E RK+ +H + N + + ++++A +HQ
Sbjct: 644 NLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQ 703
Query: 286 LKTNVERVV--QLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNT 343
+ V ++E L++ R E V D Q KL + + N
Sbjct: 704 SIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKL-EHLTGNK 762
Query: 344 THLED------IALAREKLQSXXXXXXXXXXXXSASYNKSI-KDMKHEMN--LNIAKLIE 394
+ED + L +E + A K + K MK E+N L +L+E
Sbjct: 763 ERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLE 822
Query: 395 IE-----KKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEK--ESILETKQCV 447
E K+Y + + + LQ+ ++ + + +VK+L E++EK E++ + ++
Sbjct: 823 FELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQ 882
Query: 448 -QKELESTKTDLEHRKTEIEEYKRLL-----FEKGEEIDELKSKLSTEKAIKD--IXXXX 499
+KE +T+ DL K E E+ R L FE +E + S+ E KD +
Sbjct: 883 NEKETLATQLDLAETKAESEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTVSRLE 942
Query: 500 XXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFD-NLNDVGNMIN 558
E K+ E + + +I+ L+ AF+ N+N +
Sbjct: 943 EANSMLTKDIEILRRENEELTEKMKKAEEEYKLEKEEEISNLK--AAFEKNINTERTLKT 1000
Query: 559 QQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMN 618
Q +KL E+ R++ ++ + ++++ + + + LN++ ++ + K ++ +N
Sbjct: 1001 QAVNKLAEIMNRKDFKIDRKKANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELN 1060
Score = 38.7 bits (86), Expect = 0.070
Identities = 65/319 (20%), Positives = 136/319 (42%), Gaps = 29/319 (9%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLR---TDLLESELRVKDLVR 432
+ +K + L KL +++K+ ++ + +T + LR T++ +S +++ L R
Sbjct: 524 EDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNR 583
Query: 433 ELDEKESILETKQC--------VQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKS 484
EL E+ ILE + +Q LE+ + D H I + + + EE+ LK
Sbjct: 584 ELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKH 643
Query: 485 KLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREF 544
L EK ++ + ++ E+ +N ++++T+ R
Sbjct: 644 NL--EK-VEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVN-EHKVTKARLT 699
Query: 545 GAFDNLNDVGNM-INQQRDKLFELTKRQEEYDEKLQTKENEIKR----LVESMTEQEHVL 599
++ + ++ + + KL E + +E+ + ++ E + L +S + EH+
Sbjct: 700 DKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLT 759
Query: 600 NKKEK---EIKMLNEKEEEHMNIINLLHNKLELRN-EADIDVIITLAKYKKSLTLVLEKM 655
KE+ E+K L + E+ N LL N+L+ + EAD L +K + + +
Sbjct: 760 GNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEAD-----NLKGLEKQMKQEINTL 814
Query: 656 SISNRVLKCSLLGVVTQSR 674
+ R+L+ L + Q R
Sbjct: 815 LEAKRLLEFELAQLTKQYR 833
Score = 38.3 bits (85), Expect = 0.092
Identities = 50/262 (19%), Positives = 113/262 (43%), Gaps = 19/262 (7%)
Query: 414 DDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLF 473
D++ S +++ +++ELDE+ + + ++E K L+HR I EY+R
Sbjct: 447 DEMEQKCRTSNIKLDKIMKELDEEGNQRRNLESTVSQIEKEKMLLQHR---INEYQRKAE 503
Query: 474 EKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMN 533
++ E+ +++++ST K + +++ + +
Sbjct: 504 QENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVR 563
Query: 534 LKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYD-----EKLQTKENEIKRL 588
L+ T++ + + L + + Q+R+++ E +K Q + D L+ + +
Sbjct: 564 LRKSHTEMSK--SISQLESLNREL-QERNRILENSKSQTDKDYYQLQAILEAERRDRGHD 620
Query: 589 VESMTEQEHVLNKKEKEIKMLN---EK-EEEHMNIINLLHNKLELRNEADIDVIITLAKY 644
E + + + + ++E+K L EK E E ++L++ + +N +ID+ L
Sbjct: 621 SEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKL--- 677
Query: 645 KKSLTLVLEKMSISNRVLKCSL 666
KSL LE+ ++V K L
Sbjct: 678 -KSLQQRLEQEVNEHKVTKARL 698
>AF273047-1|AAG34907.1| 623|Homo sapiens CTCL tumor antigen se20-7
protein.
Length = 623
Score = 54.0 bits (124), Expect = 2e-06
Identities = 98/494 (19%), Positives = 212/494 (42%), Gaps = 49/494 (9%)
Query: 1 MKQEELEIQQNQTDGCL--YEDLNEQESITSESHKITKLKT---VWQEKM-VTFEKSKKE 54
+KQE +++ + ++ + + L+E+E E KL+T +QE+M V EKS+ E
Sbjct: 125 VKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSE 184
Query: 55 LEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELH-IMNVAKLSPEQLLQLCAGGEP 113
+ +Q E SL +++L + + S +L + A+ ++L+L + E
Sbjct: 185 YL-KISQEKEQQESL--ALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEK 241
Query: 114 KALEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLT 173
E+ + + N N + E K K + ESL Q+ + T+ L
Sbjct: 242 SLQENKNQSKDLAVHLEAEKNKHNMEITVMVE---KHKTEL---ESLKHQQDALWTEKLQ 295
Query: 174 MKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLN 233
+ +++ E + L+ +Q + LK+ I + NE +L K+ L L+
Sbjct: 296 VLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTE--LESLS 353
Query: 234 TQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERV 293
++ +E+ K H + S++KD+ + + +L+ ++
Sbjct: 354 SELSEVLKARHKLEEE----------------------LSVLKDQTDKMKQELEAKMDE- 390
Query: 294 VQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLE----DI 349
Q +Q S E ++ + L + + +K++ H+E DI
Sbjct: 391 -QKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADI 449
Query: 350 ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTL 409
+ +LQ SA++ ++ K + ++ KL+++E + ++ +
Sbjct: 450 KRSEGELQQASAKLDVFQSYQSATHEQT-KAYEEQLAQLQQKLLDLETERILLTKQVAEV 508
Query: 410 QENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYK 469
+ D+ T+L +++V+DL+++L+++ S +E K V+ + ++ LE E E+ K
Sbjct: 509 EAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQK--VKSLTQVYESKLEDGNKEQEQTK 566
Query: 470 RLLFEKGEEIDELK 483
++L EK I +++
Sbjct: 567 QILVEKENMILQMR 580
Score = 41.1 bits (92), Expect = 0.013
Identities = 58/373 (15%), Positives = 142/373 (38%), Gaps = 13/373 (3%)
Query: 275 MKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNK 334
M + L E ++ R+ Q+ E+ R + ER + ++ K
Sbjct: 36 MHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRK 95
Query: 335 LTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIE 394
L + + +E + E++ S + + L+ +L
Sbjct: 96 LKAEMDEQIKTIEKTS-EEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELAR 154
Query: 395 IEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKE--LE 452
E++ ++ ++ +E + ++ L +S+ + +E +++ES+ + +QK+ L
Sbjct: 155 KEQELTKKLQTRE--REFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILT 212
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXX 512
++ L + E E Y+ + E ++ KS + KD+
Sbjct: 213 ESENKLRDLQQEAETYRTRILELESSLE--KSLQENKNQSKDLAVHLEAEKNKHNMEITV 270
Query: 513 XXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQ--RDK--LFE-- 566
+K + L K Q+ + + + L + + +DK +F+
Sbjct: 271 MVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAH 330
Query: 567 LTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNK 626
+ + E+ EKL K+ E++ L ++E +K E+E+ +L ++ ++ + ++
Sbjct: 331 IEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDE 390
Query: 627 LELRNEADIDVII 639
+ ++ +D II
Sbjct: 391 QKNHHQQQVDSII 403
Score = 39.1 bits (87), Expect = 0.053
Identities = 107/601 (17%), Positives = 235/601 (39%), Gaps = 42/601 (6%)
Query: 42 QEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQ-------KVNLPSAEELH-I 93
Q+K + ++K+++ + E A LR+ ++M G+ K + EEL
Sbjct: 23 QDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKA 82
Query: 94 MNVAKLSPEQLLQLCAGGEP--KALEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRK 151
++ A+ + E +L A + K +E ++ + +++ +L + +VD +++ +
Sbjct: 83 LSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQ-QELSRVKQEVVDVMKKS---SE 138
Query: 152 EIINWFESLMSQEKGISTKTLTMKIKEFNAE-NDLLKSSLDQLRTEFLKEINDIIDCLRK 210
E I + L +E + LT K++ E + +K +L++ ++E+LK + K
Sbjct: 139 EQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQE------K 192
Query: 211 NANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXX 270
E++AL+ + L++ + +++++ + +
Sbjct: 193 EQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKD 252
Query: 271 XXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWS--LERTVXXXXXXXXXXXEDF 328
++ ++ ++ VE+ +L+ + W+ L+ E
Sbjct: 253 LAVHLEAEKNKHNMEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKC 312
Query: 329 DQELNKLTQSIKDN-TTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNL 387
+QE L + + H+E++ EK S+ ++ +K +H++
Sbjct: 313 EQEKETLLKDKEIIFQAHIEEM---NEKTLEKLDVKQTELESLSSELSEVLK-ARHKLEE 368
Query: 388 NIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCV 447
++ L + K +E K Q+N + D + E V E K+ I + + +
Sbjct: 369 ELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLL 428
Query: 448 Q---KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE----KAIKDIXXXXX 500
+ K L+ + +E+ + +I+ + L + ++D +S S KA ++
Sbjct: 429 KERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQ 488
Query: 501 XXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLN---DVGNMI 557
E+Q K EL K Q+ L + N V ++
Sbjct: 489 QKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLT 548
Query: 558 NQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNK----KEKEIKMLNEKE 613
KL + K QE+ + L KEN I ++ E ++ +L + KE I +LNE+
Sbjct: 549 QVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEY 608
Query: 614 E 614
E
Sbjct: 609 E 609
>Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein.
Length = 1937
Score = 53.6 bits (123), Expect = 2e-06
Identities = 85/463 (18%), Positives = 177/463 (38%), Gaps = 26/463 (5%)
Query: 164 EKGIST-KTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRT 222
EK ++T K K K+ A+++ + L++ LKE ND+ ++ A+ + R
Sbjct: 849 EKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERC 908
Query: 223 KELSCALSDLN------TQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMK 276
++L L T+ AE ++I++ + + + ++
Sbjct: 909 EQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 968
Query: 277 DRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLT 336
E+++K E + L+ + + E +L+ T ED L K
Sbjct: 969 KEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQET-HQQTLDDLQAEEDKVNILTKAK 1027
Query: 337 QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIE 396
++ LE +KL+ +S DM+++ +++
Sbjct: 1028 TKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQ-------QLD 1080
Query: 397 KKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKT 456
+K E L I+D + ++ + ++K+L ++E +E ++ + + E ++
Sbjct: 1081 EKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRS 1140
Query: 457 DLEHRKTEIEEYKRLLFEKGEEID---ELKSKLSTE--KAIKDIXXXXXXXXXXXXXXXX 511
DL E+EE L E G EL K E K +D+
Sbjct: 1141 DLSR---ELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRK 1197
Query: 512 XXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQ 571
Q+ + L+ + ++L+ D+L+ I++ + L ++ +
Sbjct: 1198 KHADSMAELGEQIDNLQRVKQKLEKEKSELKM--ETDDLSSNAEAISKAKGNLEKMCRSL 1255
Query: 572 EEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEI-KMLNEKE 613
E+ +L+TKE E +RL+ +T Q L + E + L+EK+
Sbjct: 1256 EDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKD 1298
Score = 49.6 bits (113), Expect = 4e-05
Identities = 68/380 (17%), Positives = 159/380 (41%), Gaps = 24/380 (6%)
Query: 277 DRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLT 336
++L + + QL+ ++ V + E+ +E + +R + +D + L K+
Sbjct: 909 EQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 968
Query: 337 QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHE---MNLNIAKLI 393
+ ++++ L ++ +++ D++ E +N+
Sbjct: 969 KEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKT 1028
Query: 394 EIEKKYND---SIEEKKTLQENID----DLRTDLL---ESELRVKDLVRELDEK--ESIL 441
++E++ +D S+E++K L+ +++ L DL ES + +++ ++LDEK +
Sbjct: 1029 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEF 1088
Query: 442 ETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEID-ELKSKLSTEKAIKDIXXXXX 500
E + K + +++ +K +I+E + + E GEEI+ E S+ EK D+
Sbjct: 1089 EISNLISKIEDEQAVEIQLQK-KIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELE 1147
Query: 501 XXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNM--IN 558
+ + + + +L+ Q A +M +
Sbjct: 1148 EISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELG 1207
Query: 559 QQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKK----EKEIKMLNEKEE 614
+Q D L + ++ E+ +L+ + +++ E++++ + L K E ++ L KEE
Sbjct: 1208 EQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEE 1267
Query: 615 EHMNIIN-LLHNKLELRNEA 633
E +IN L + L+ EA
Sbjct: 1268 EQQRLINDLTAQRARLQTEA 1287
Score = 48.0 bits (109), Expect = 1e-04
Identities = 106/592 (17%), Positives = 220/592 (37%), Gaps = 31/592 (5%)
Query: 23 EQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQK 82
E+ + ++ +T+ E + K KK L++ Q ++ L+ K+ +L K
Sbjct: 970 EKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLD---DLQAEEDKVNIL-TK 1025
Query: 83 VNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHST-LDNKVTFDVNKLLNIPNSLVD 141
+++ + L E+ L++ + LE L + T D+ N L +
Sbjct: 1026 AKTKLEQQVDDLE-GSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDME---NDKQQLDE 1081
Query: 142 KCEETLFKRKEIINWFESLMSQEKGISTKT--LTMKIKEFNAENDLLKSS---LDQLRTE 196
K E+ F+ +I+ E + E + K L +I+E E + ++S ++ R++
Sbjct: 1082 KLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSD 1141
Query: 197 FLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRN 256
+E+ +I + L + T A K+ L E Q H A R
Sbjct: 1142 LSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQ-HEA---MVAALRK 1197
Query: 257 XXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXX 316
+K +L + + +LK + + A+ +A+ + R++
Sbjct: 1198 KHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLED 1257
Query: 317 XXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNK 376
E+ + +N LT T + + +L AS +
Sbjct: 1258 QVSELKTKEEEQQRLINDLTAQRARLQTEAGEYS---RQLDEKDALVSQLSRSKQAS-TQ 1313
Query: 377 SIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDE 436
I+++KH++ + S + L+E ++ + E + + E+ +
Sbjct: 1314 QIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQ 1373
Query: 437 KESILETKQCVQ-KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDI 495
+ ET + +ELE K L R E EE+ + K +++ K +L E ++D+
Sbjct: 1374 WRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNE--VEDL 1431
Query: 496 XXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGN 555
S+ K YEE + + +Q L V N
Sbjct: 1432 MLDVERSNAACAALDKKQRNFDKVL-SEWKQKYEE-TQAELEASQKESRSLSTELFKVKN 1489
Query: 556 MINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK 607
+ + D+L E +R+ ++ LQ + +++ + +Q H L K +K+++
Sbjct: 1490 VYEESLDQL-ETLRRE---NKNLQQEISDLTEQIAEGGKQIHELEKIKKQVE 1537
Score = 46.4 bits (105), Expect = 3e-04
Identities = 59/285 (20%), Positives = 128/285 (44%), Gaps = 30/285 (10%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLV 431
A+ + + K E+ + AK E+E+K ++EK LQ + L ++E R + L+
Sbjct: 853 ATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLI 912
Query: 432 RELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
+ + E+ ++ +E E +L +K ++E+ E ++ID+L +L+ K
Sbjct: 913 KNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDE---CSELKKDIDDL--ELTLAKV 967
Query: 492 IKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQL-REFGAFDNL 550
K+ E+++K+ EE+ L I +L +E A
Sbjct: 968 EKE----------------------KHATENKVKNLTEEMAGLDETIAKLSKEKKALQET 1005
Query: 551 N-DVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKML 609
+ + + + DK+ LTK + + ++++ E +++ + + E K E ++K+
Sbjct: 1006 HQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLA 1065
Query: 610 NEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEK 654
E + N L KLE + E +I +I+ + ++++ + L+K
Sbjct: 1066 QESTMDMENDKQQLDEKLE-KKEFEISNLISKIEDEQAVEIQLQK 1109
Score = 42.7 bits (96), Expect = 0.004
Identities = 44/241 (18%), Positives = 98/241 (40%), Gaps = 6/241 (2%)
Query: 391 KLIEIEKKYNDSIEEKKTLQ---ENIDDLRTDLLESELRVKDLVRELDEKESILETKQC- 446
+L +++ Y +S+++ +TL+ +N+ +DL E + EL++ + +E ++C
Sbjct: 1483 ELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCE 1542
Query: 447 VQKELESTKTDLEHRKTEIEEYKRLLFEKGEEID-ELKSKLSTEKAIKDIXXXXXXXXXX 505
+Q LE + LEH + +I + L + E+D ++ K +K
Sbjct: 1543 IQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQS 1602
Query: 506 XXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLF 565
+ +M+ E+ N +L + N + ++ + + L
Sbjct: 1603 TLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAA-ESLRNYRNTQGILKETQLHLD 1661
Query: 566 ELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHN 625
+ + QE+ E+L E L + E L + E+ K+ ++ + + LLH
Sbjct: 1662 DALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHT 1721
Query: 626 K 626
+
Sbjct: 1722 Q 1722
Score = 35.1 bits (77), Expect = 0.86
Identities = 40/211 (18%), Positives = 87/211 (41%), Gaps = 11/211 (5%)
Query: 285 QLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTT 344
Q + E +L+ AL +A SE + + E+ ++ KL Q +++
Sbjct: 1349 QYEEEQEGKAELQRALSKANSE---VAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 1405
Query: 345 HLEDI---ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYND 401
H+E + + EK + N + + + L E ++KY +
Sbjct: 1406 HVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEE 1465
Query: 402 SIEEKKTLQENIDDLRTDLLESELRVKDLVRE-LDEKESILETKQCVQKELESTKTDLEH 460
+ E + Q+ L T+L +VK++ E LD+ E++ + +Q+E+ +
Sbjct: 1466 TQAELEASQKESRSLSTELF----KVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAE 1521
Query: 461 RKTEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
+I E +++ + +E E+++ L +A
Sbjct: 1522 GGKQIHELEKIKKQVEQEKCEIQAALEEAEA 1552
>M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle
myosin heavy chain (NMHC) mRNA, 3' end. ).
Length = 1247
Score = 53.6 bits (123), Expect = 2e-06
Identities = 117/638 (18%), Positives = 242/638 (37%), Gaps = 37/638 (5%)
Query: 1 MKQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQN 60
M+ E L+ Q L E L + + +E+ ++ T ++++ E+ +LE R
Sbjct: 155 MEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQEL---EEICHDLEARVE 211
Query: 61 QVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHST 120
+ E Y L+ +KM+ N+ EE + QL ++ + K LE
Sbjct: 212 EEEERYQHLQAEKKKMQQ-----NIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQ 266
Query: 121 LDNKVTFDVN-KLLNIPNSLVDKCEE---TLFKRKEIINWFESLMSQEKGISTKTLTMKI 176
+ + D N KL L D+ E L + +E L ++ + + T L ++
Sbjct: 267 I---ILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITD-LEERL 322
Query: 177 KEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQN 236
+ + L+ + +L + + I + + A M L + +EL AL+ + +
Sbjct: 323 RREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEA 382
Query: 237 AEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQL 296
A+ K + + + K L LKT +E +
Sbjct: 383 AQ--KNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDS 440
Query: 297 EAALEQARSESWS----LERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALA 352
AA ++ RS+ L++T+ ++ Q+ ++ + + + + +
Sbjct: 441 TAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKAN 500
Query: 353 REKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDS------IEEK 406
EK + + +D +H+ A+L E++ K+N+ + +K
Sbjct: 501 LEKAKQTLENERGELANEVKVLLQGGRDSEHKRKKVEAQLQELQVKFNEGERVRTELADK 560
Query: 407 KT-LQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEI 465
T LQ +D++ L +S+ + L ++ ES L+ Q + +E K L + ++
Sbjct: 561 VTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQV 620
Query: 466 EEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMK 525
E+ K E+ EE +E ++K + EK I + + K
Sbjct: 621 EDEKNSFREQLEEEEE-EAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQK 679
Query: 526 SY------YEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQ 579
+EE + +++ + + L+D+ ++ QR L K+Q+++D+ L
Sbjct: 680 DLEGLSQRHEEKVAAYDKLEKTKT-RLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLA 738
Query: 580 TKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHM 617
++ + E E +KE + L EE M
Sbjct: 739 EEKTISAKYAEERDRAEAEAREKETKALSLARALEEAM 776
Score = 47.6 bits (108), Expect = 2e-04
Identities = 56/283 (19%), Positives = 121/283 (42%), Gaps = 15/283 (5%)
Query: 382 KHE-MNLNIAKLIEIEKKYNDSIEE-KKTLQENIDDLRTDLLESELRVKDLVRELDEKES 439
KHE M ++ + + E+K +E+ ++ L+ + DL + E + ++ +L +L +KE
Sbjct: 310 KHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEE 369
Query: 440 ILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEID-ELKSKLSTEKAIKDIXXX 498
L+ + E E+ + ++ +K I E + + E E+++ E S+ EK +D+
Sbjct: 370 ELQAA-LARVEEEAAQKNMALKK--IRELESQISELQEDLESERASRNKAEKQKRDLGEE 426
Query: 499 XXXXXXXXXXXXXXXXXXXXXRESQ-------MKSYYEELMNLKNQITQLREFGAFDNLN 551
R + K+ EE + QI ++R+ + +
Sbjct: 427 LEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHS-QAVE 485
Query: 552 DVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNE 611
++ + Q + L K ++ + + NE+K L++ + EH K E +++ L
Sbjct: 486 ELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGGRDSEHKRKKVEAQLQELQV 545
Query: 612 KEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEK 654
K E + L +K+ + + ++D + L S + L K
Sbjct: 546 KFNEGERVRTELADKV-TKLQVELDNVTGLLSQSDSKSSKLTK 587
Score = 42.7 bits (96), Expect = 0.004
Identities = 53/310 (17%), Positives = 126/310 (40%), Gaps = 21/310 (6%)
Query: 190 LDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHH 249
L++ +T +E++D++ L L+ + K+ L++ T +A+ ++ +
Sbjct: 698 LEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAK-----YAEERD 752
Query: 250 RPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWS 309
R A K L R Q +T +E ++ + + ++ E
Sbjct: 753 RAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEK 812
Query: 310 LERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLE-DIALAREKLQSXXXXXXXXXX 368
+R + E+ + EL Q+ +D LE ++ + + +
Sbjct: 813 SKRALEQQVEEMKTQLEELEDEL----QATEDAKLRLEVNLQAMKAQFERDLQGRDEQSE 868
Query: 369 XXSASYNKSIKDMKHEM-------NLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLL 421
+ +++M+ E+ ++ +A ++E D + +N D+ L
Sbjct: 869 EKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLR 928
Query: 422 ESELRVKDLVRELDE----KESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGE 477
+ + ++KD +RELD+ +E IL + +K+L+S + ++ + E+ +R + +
Sbjct: 929 KLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQ 988
Query: 478 EIDELKSKLS 487
E DEL +++
Sbjct: 989 ERDELADEIA 998
Score = 37.5 bits (83), Expect = 0.16
Identities = 69/344 (20%), Positives = 139/344 (40%), Gaps = 21/344 (6%)
Query: 158 ESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKN------ 211
E +M++E+ + + ++ K+ AEN L++ ++ L+++ + E + + L+
Sbjct: 131 EEMMAKEEEL----VKVREKQLAAENRLME--METLQSQLMAEKLQLQEQLQAETELCAE 184
Query: 212 ANETMA-LQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXX 270
A E A L + +EL DL + E ++ + +N
Sbjct: 185 AEELRARLTAKKQELEEICHDLEARVEEEEERYQHLQAEKKKMQQNIQELEEQLEEEESA 244
Query: 271 XXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQ 330
+ ++++ E +LK E + LE + E LE + E+ +
Sbjct: 245 RQKLQLEKVT-TEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEE-EEKSK 302
Query: 331 ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH---EMNL 387
L KL + T LE+ EK + S + I +++ E+ +
Sbjct: 303 SLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKM 362
Query: 388 NIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRV--KDLVRELDEKESILETKQ 445
+AK E + +EE+ Q+N+ + LES++ +DL E + + K+
Sbjct: 363 QLAKKEEELQAALARVEEEAA-QKNMALKKIRELESQISELQEDLESERASRNKAEKQKR 421
Query: 446 CVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
+ +ELE+ KT+LE + L ++ +E++ LK L E
Sbjct: 422 DLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEE 465
Score = 37.1 bits (82), Expect = 0.21
Identities = 98/504 (19%), Positives = 198/504 (39%), Gaps = 46/504 (9%)
Query: 28 TSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPS 87
T S +I +L+ E + K ++EL+ +V E A +K++ L +++
Sbjct: 344 TDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQIS-EL 402
Query: 88 AEELHIMNVAKLSPEQLLQLCAGGEPKALE---HSTLDNKVTFDVNKLLNIPNSLVDKCE 144
E+L ++ E+ + G E +AL+ TLD+ T +L + V+ +
Sbjct: 403 QEDLESERASRNKAEKQKR-DLGEELEALKTELEDTLDS--TAAQQELRSKREQEVNILK 459
Query: 145 ETLFKRKEIINWFESLMSQEKGISTKTLTMKI---KEFNAENDLLKSSLDQLRTEFLKEI 201
+TL + + M Q+ + + L ++ K A + K +L+ R E E+
Sbjct: 460 KTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEV 519
Query: 202 NDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXX 261
++ R + ++ ++ + +EL ++ E+ ++
Sbjct: 520 KVLLQGGRDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVT-GLLSQS 578
Query: 262 XXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXX 321
S ++ +L + L+ + + L L+Q E S +
Sbjct: 579 DSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEEA 638
Query: 322 XXXXED----FDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKS 377
E ++ + + ++D+ LE + KLQ A+Y+K
Sbjct: 639 KHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKL 698
Query: 378 IK--------------DMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQ----ENIDDLRTD 419
K D+ H+ + L + +KK++ + E+KT+ E D +
Sbjct: 699 EKTKTRLQQELDDLLVDLDHQRQ-SACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAE 757
Query: 420 LLESELRVKDLVRELDE---KESILE--TKQ--CVQKELESTKTDLEHRKTEIEEYKRLL 472
E E + L R L+E +++ LE KQ ++L S+K D+ E+E+ KR L
Sbjct: 758 AREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRAL 817
Query: 473 FEKGEE----IDELKSKL-STEKA 491
++ EE ++EL+ +L +TE A
Sbjct: 818 EQQVEEMKTQLEELEDELQATEDA 841
Score = 35.1 bits (77), Expect = 0.86
Identities = 50/248 (20%), Positives = 98/248 (39%), Gaps = 8/248 (3%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLL--ESELRVKDLVRELDEKESILETKQCVQ 448
+L+E+E + + EK LQE + T+L ELR + L + E E I +
Sbjct: 153 RLMEMETLQSQLMAEKLQLQEQL-QAETELCAEAEELRAR-LTAKKQELEEICHDLEARV 210
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXX 508
+E E L+ K ++++ + L E+ EE + + KL EK +
Sbjct: 211 EEEEERYQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILE 270
Query: 509 XXX-XXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDN--LNDVGNMINQQRDKLF 565
E ++ + L + + L + + D+ + ++ +
Sbjct: 271 DQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQ 330
Query: 566 ELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHN 625
EL K + + + ++I L + E + L KKE+E++ + EE N+
Sbjct: 331 ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALK 390
Query: 626 KL-ELRNE 632
K+ EL ++
Sbjct: 391 KIRELESQ 398
>BC128578-1|AAI28579.1| 751|Homo sapiens RRBP1 protein protein.
Length = 751
Score = 53.6 bits (123), Expect = 2e-06
Identities = 45/221 (20%), Positives = 99/221 (44%), Gaps = 13/221 (5%)
Query: 278 RLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQ 337
RL E Q+ + ++L A+EQ + ++ L + ++L+ LTQ
Sbjct: 329 RLKELESQVSGLEKEAIELREAVEQQKVKNNDLREKNWKAMEALATAEQACKEKLHSLTQ 388
Query: 338 SIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAK------ 391
+ +++ L + + +++ +Y + ++D+K E + K
Sbjct: 389 AKEESEKQL--CLIEAQTMEALLALLPELSVLAQQNYTEWLQDLK-EKGPTLLKHPPAPA 445
Query: 392 --LIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETK-QCVQ 448
++ K ++ E + TLQ D R+ L E+E ++DL + ++E+E + K +
Sbjct: 446 EPSSDLASKLREAEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEEQVWRAKVGAAE 505
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
+EL+ ++ ++H + +E+ K L E +++ E S L E
Sbjct: 506 EELQKSRVTVKHLEEIVEKLKGEL-ESSDQVREHTSHLEAE 545
>AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain protein.
Length = 1938
Score = 53.6 bits (123), Expect = 2e-06
Identities = 61/354 (17%), Positives = 135/354 (38%), Gaps = 14/354 (3%)
Query: 283 EHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDN 342
E+++K E + LE + + E SL+ ED L K+ ++
Sbjct: 976 ENKVKNLSEEMTALEENISKLTKEKKSLQEA-HQQTLDDLQVEEDKVNGLIKINAKLEQQ 1034
Query: 343 TTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDS 402
T LE +KL++ +SI D+++E +IE+K
Sbjct: 1035 TDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENEKQ-------QIEEKLKKK 1087
Query: 403 IEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRK 462
E LQ IDD + L+ + ++K+L ++E E +E + ++ ++E ++DL
Sbjct: 1088 EFELSQLQARIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLAREL 1147
Query: 463 TEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRES 522
EI E RL G +++ E + + +
Sbjct: 1148 EEISE--RLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVA 1205
Query: 523 QMKSYYEELMNLKNQITQLRE--FGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQT 580
++ + L +K ++ + + D++ +++ + + + E+ +++
Sbjct: 1206 ELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKA 1265
Query: 581 KENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEAD 634
K+ + +L+ + Q+ L + E+ + EE+ I L +K L + +
Sbjct: 1266 KDEQQTQLIHDLNMQKARLQTQNGELS--HRVEEKESLISQLTKSKQALTQQLE 1317
Score = 51.2 bits (117), Expect = 1e-05
Identities = 70/303 (23%), Positives = 129/303 (42%), Gaps = 14/303 (4%)
Query: 332 LNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAK 391
L K ++ K+ T ED +E+L + S + D++ ++
Sbjct: 843 LLKSAEAEKEMATMKEDFERTKEEL-ARSEARRKELEEKMVSLLQEKNDLQLQVQSETEN 901
Query: 392 LIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLV---RELDEKESILETKQCVQ 448
L++ E++ I+ K L+ + +L L E E +LV R L++K S L K+ +
Sbjct: 902 LMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSL--KRDID 959
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXX 508
+LE T T +E K E + L E+ ++E SKL+ EK K +
Sbjct: 960 -DLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEK--KSLQEAHQQTLDDLQV 1016
Query: 509 XXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELT 568
++++ ++L Q +LR G+ + ++ + +L
Sbjct: 1017 EEDKVNGLIKI-NAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGD-LKMSQESIMDLE 1074
Query: 569 KRQEEYDEKLQTKENEIKRLVESM-TEQEHVL--NKKEKEIKMLNEKEEEHMNIINLLHN 625
+++ +EKL+ KE E+ +L + EQ H L KK KE++ E+ EE + + L
Sbjct: 1075 NEKQQIEEKLKKKEFELSQLQARIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRA 1134
Query: 626 KLE 628
K+E
Sbjct: 1135 KIE 1137
Score = 44.0 bits (99), Expect = 0.002
Identities = 96/523 (18%), Positives = 200/523 (38%), Gaps = 54/523 (10%)
Query: 177 KEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQN 236
+E N+E K +L+ + ++I+D+ L K E A + + K LS ++ L
Sbjct: 934 EEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENI 993
Query: 237 AEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQL 296
+++ K+ S A++ I +L + L+ ++E+ +L
Sbjct: 994 SKLTKEKKSLQE----AHQQTLDDLQVEEDKVNGLIKI-NAKLEQQTDDLEGSLEQEKKL 1048
Query: 297 EAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKL 356
A LE+A+ R + D + E ++ + +K L + +
Sbjct: 1049 RADLERAK-------RKLEGDLKMSQESIMDLENEKQQIEEKLKKKEFELSQLQARIDDE 1101
Query: 357 QSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDL 416
Q S + K IK+++ A++ E+E++ IE + TL+ I+
Sbjct: 1102 Q-----------VHSLQFQKKIKELQ-------ARIEELEEE----IEAEHTLRAKIEKQ 1139
Query: 417 RTDLLESELRVKDLVRELDEKESI-LETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEK 475
R+DL + + + E S +E + + E + + DLE + E L +K
Sbjct: 1140 RSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKK 1199
Query: 476 --------GEEIDEL---KSKLSTEKA-IK---DIXXXXXXXXXXXXXXXXXXXXXXXXR 520
GE+ID L K KL EK+ +K D +
Sbjct: 1200 QADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQ 1259
Query: 521 ESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQT 580
S++K+ E+ L + + + N ++ + + ++ + +LTK ++ ++L+
Sbjct: 1260 FSEIKAKDEQQTQLIHDLNMQKARLQTQN-GELSHRVEEKESLISQLTKSKQALTQQLEE 1318
Query: 581 KENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIIT 640
+ +++ ++ H L + +L E+ EE L L ++A+ +V
Sbjct: 1319 LKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRAL---SKANSEVAQW 1375
Query: 641 LAKYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRTLRKNMSGL 683
KY+ E++ + + L L ++ T + L
Sbjct: 1376 KTKYETDAIQRTEELEEAKKKLAQRLQEAEEKTETANSKCASL 1418
Score = 43.6 bits (98), Expect = 0.002
Identities = 69/329 (20%), Positives = 139/329 (42%), Gaps = 30/329 (9%)
Query: 326 EDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEM 385
E+ + +++LT+S + T LE++ E+ ++ S +++ E
Sbjct: 1296 EEKESLISQLTKSKQALTQQLEELKRQMEE-ETKAKNAMAHALQSSRHDCDLLREQYEEE 1354
Query: 386 NLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLE-SELRVKDLVRELDEKE------ 438
A+L K N + + KT E RT+ LE ++ ++ ++E +EK
Sbjct: 1355 QEAKAELQRALSKANSEVAQWKTKYETDAIQRTEELEEAKKKLAQRLQEAEEKTETANSK 1414
Query: 439 --SILETKQCVQKELESTKTDLEHRKT-------EIEEYKRLLFEKGEEIDELKSKLSTE 489
S+ +TKQ +Q E+E DLE T + + ++L E +++DE +++L E
Sbjct: 1415 CASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAEL--E 1472
Query: 490 KAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDN 549
A K+ R + K+ EE+ +L QI + + N
Sbjct: 1473 AAQKESRSLSTELFKMRNAYEEVVDQLETLRR-ENKNLQEEISDLTEQIAETGK-----N 1526
Query: 550 LNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKR----LVESMTEQEHVLNKKEKE 605
L + + +L EE + L+ +E++I R L + +E + + +K++E
Sbjct: 1527 LQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEE 1586
Query: 606 IKMLNEKEEEHMNII-NLLHNKLELRNEA 633
I+ L + + ++L ++ RN+A
Sbjct: 1587 IEQLKRNSQRAAEALQSVLDAEIRSRNDA 1615
Score = 39.9 bits (89), Expect = 0.030
Identities = 61/353 (17%), Positives = 136/353 (38%), Gaps = 24/353 (6%)
Query: 151 KEIINWFESLMSQEKGISTKT--LTMKIKEFNA---ENDLLKSSLDQLRTEFLKEINDII 205
+E+++ E+L + K + + LT +I E E + K ++Q +++ + ++
Sbjct: 1493 EEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVE 1552
Query: 206 DCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXX 265
L ++ + +QL ++ L + E +Q+ A ++
Sbjct: 1553 GSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSR 1612
Query: 266 XXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXX 325
M+ L+ E QL + ++ + + L + + + +
Sbjct: 1613 NDALRLKKKMEGDLNEMEIQLGHSNRQMAETQRHLRTVQGQLKDSQLHLDDALRSNEDLK 1672
Query: 326 EDF---DQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMK 382
E ++ L + +++ LE R +L S N S+ + K
Sbjct: 1673 EQLAIVERRNGLLLEELEEMKVALEQTERTR-RLSEQELLDASDRVQLLHSQNTSLINTK 1731
Query: 383 HEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILE 442
++ +IA + + + +SI+E + +E TD + + ++L +E D +
Sbjct: 1732 KKLEADIA---QCQAEVENSIQESRNAEEKAKKAITD---AAMMAEELKKEQDTSAHLER 1785
Query: 443 TKQCVQKELESTKTDLEHRKTEIEEY-----KRLLFEKGEEIDELKSKLSTEK 490
K K LE T DL+HR E E+ K+ + + + EL+++L E+
Sbjct: 1786 MK----KNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQ 1834
>AF006751-1|AAC25977.1| 977|Homo sapiens ES/130 protein.
Length = 977
Score = 53.6 bits (123), Expect = 2e-06
Identities = 45/221 (20%), Positives = 99/221 (44%), Gaps = 13/221 (5%)
Query: 278 RLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQ 337
RL E Q+ + ++L A+EQ + ++ L + ++L+ LTQ
Sbjct: 555 RLKELESQVSGLEKEAIELREAVEQQKVKNNDLREKNWKAMEALATAEQACKEKLHSLTQ 614
Query: 338 SIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAK------ 391
+ +++ L + + +++ +Y + ++D+K E + K
Sbjct: 615 AKEESEKQL--CLIEAQTMEALLALLPELSVLAQQNYTEWLQDLK-EKGPTLLKHPPAPA 671
Query: 392 --LIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETK-QCVQ 448
++ K ++ E + TLQ D R+ L E+E ++DL + ++E+E + K +
Sbjct: 672 EPSSDLASKLREAEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEEQVWRAKVGAAE 731
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
+EL+ ++ ++H + +E+ K L E +++ E S L E
Sbjct: 732 EELQKSRVTVKHLEEIVEKLKGEL-ESSDQVREHTSHLEAE 771
>U19769-1|AAA82889.1| 3210|Homo sapiens CENP-F kinetochore protein
protein.
Length = 3210
Score = 53.2 bits (122), Expect = 3e-06
Identities = 66/357 (18%), Positives = 132/357 (36%), Gaps = 10/357 (2%)
Query: 278 RLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQ 337
RL E ++K V + +L+ LE+A+ E E+ + +DQ K T
Sbjct: 300 RLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTA 359
Query: 338 SIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEK 397
+ ED++ R+ +S + + + + + I+++
Sbjct: 360 LEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKA 419
Query: 398 KYNDSIEEKK----TLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELES 453
+ +++ K LQ +D L + + E +++ ++L E + Q + EL
Sbjct: 420 RLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENEL-- 477
Query: 454 TKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXX 513
+ +E K E K +K E+ L+++L K +
Sbjct: 478 -RRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETM 536
Query: 514 XXXXXXRESQMKSYYEELMNLKNQITQLREFG--AFDNLNDVGNMINQQRDKLFELTKRQ 571
+ +Q ++ L LK + L + + D L + I Q DKL + K
Sbjct: 537 LRDLQEKINQQENSL-TLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKES 595
Query: 572 EEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
+ L+ K+ E + L E T ++ EK + + ++E + IN L L+
Sbjct: 596 KALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLK 652
Score = 44.0 bits (99), Expect = 0.002
Identities = 143/660 (21%), Positives = 257/660 (38%), Gaps = 64/660 (9%)
Query: 30 ESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAE 89
ESH+ L + + EK++ L+ + V EL + K++ L + S
Sbjct: 2088 ESHQSECLHCIQVAEAEVKEKTEL-LQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLT 2146
Query: 90 ELHIMN-VAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCE---- 144
+ + N +A+L+ E+ L L E S D + +V+K L +LV+K E
Sbjct: 2147 KCELENQIAQLNKEKEL-LVKESESLQARLSESDYE-KLNVSKALEA--ALVEKGEFALR 2202
Query: 145 --ETLFKRKEIINWFESLMSQEKGISTKTLTM--KIKEFNAENDLLKSSLDQLRTEF-LK 199
T + ++ E L + + K L + K+KE END LK ++ L E +
Sbjct: 2203 LSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMS 2262
Query: 200 EIND---IIDCLRKNAN-ETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANR 255
E N I+D A ET+ Q+ S + +L+ K+ + +
Sbjct: 2263 EENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKE------NLTKQIQ 2316
Query: 256 NXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQ-LEAALEQARSESWSLERTV 314
S+++++ +AE Q+K + V+ L+ L++ +L
Sbjct: 2317 EKQGQLSELDKLLSSFKSLLEEK-EQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQ 2375
Query: 315 XXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASY 374
++E ++L SI+ LE A EK Q +
Sbjct: 2376 EIMKATEQSLDPPIEEE-HQLRNSIEKLRARLE----ADEKKQLCVLQQLKESEHHADLL 2430
Query: 375 NKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVREL 434
+++++ E+ + + +S E +TL+ I+ + L EL D+V
Sbjct: 2431 KGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLEL---DVVTIR 2487
Query: 435 DEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKD 494
EKE + +QKE E ++LE + E +L EK +E ++K K ST +
Sbjct: 2488 SEKEDLTNE---LQKEQERI-SELEIINSSFEN---ILQEKEQEKVQMKEKSSTAM---E 2537
Query: 495 IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVG 554
+ +E + S E L K Q+ Q L++
Sbjct: 2538 MLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQ--------GLDEAK 2589
Query: 555 NMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNK---KEKEIKMLNE 611
N + + L + E+ +KL+ K+ EI RL + +QE +++K E E ++ E
Sbjct: 2590 NNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKE 2649
Query: 612 KEEEHMNIINLLHNKLEL---RNEADIDVIITLAKYKKSLTLVLE-----KMSISNRVLK 663
+ E N+ L K+++ +N + D + L K+L LE KMS +V K
Sbjct: 2650 QNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNK 2709
Score = 42.7 bits (96), Expect = 0.004
Identities = 91/479 (18%), Positives = 194/479 (40%), Gaps = 33/479 (6%)
Query: 28 TSESHKITKLKTVWQEKMVTFEKSKKELEDR-QNQVMELYASLRNTHRKMKLLGQKVNLP 86
+S H + +LK QE ELE R Q E+ + N ++++L +K +
Sbjct: 274 SSSPHLLDQLKAQNQE----LRNKINELELRLQGHEKEMKGQV-NKFQELQLQLEKAKVE 328
Query: 87 SAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKL-LNIPNSLVDKCE- 144
E+ ++N + ++L++ A + + +++ L+ K+ L N+ +C
Sbjct: 329 LIEKEKVLNKCR---DELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSL 385
Query: 145 ETLFKRKEIINWFESLMSQEKGIST---------KTLTMKIKEFNAENDLLKSSLDQLRT 195
E K KE + E L Q++ T LT ++++ +++L++ LD+L +
Sbjct: 386 EQKIKEKEK-EFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTS 444
Query: 196 EFLKEINDIIDCLRKNANETMALQ---LRTKELSCALSDLNTQNAEMRKQIHSGDHHRPY 252
+ N++ + +K A Q ++ EL ++ ++ +N ++ HS R
Sbjct: 445 VKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKS--HSEQKAREV 502
Query: 253 ANRNXXXXXXXX-XXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAAL--EQARSESWS 309
+ MK + + E L+ E++ Q E +L E+ +
Sbjct: 503 CHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVAD 562
Query: 310 LERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXX 369
LE+ +Q +KL+++ K++ L + L +++ +
Sbjct: 563 LEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCW 622
Query: 370 XSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKD 429
S + K + M+ E +K+ +E + E + L D + +++
Sbjct: 623 KSEN-EKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRN 681
Query: 430 LVRELDEKESILETKQCVQKELESTK--TDLEHRKTEIEEYKRLLFEKGEEIDELKSKL 486
L LD K +ET++ EL+ +D +H+K EIE + ++++L+ KL
Sbjct: 682 LHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQK-EIENMCLKTSQLTGQVEDLEHKL 739
Score = 42.3 bits (95), Expect = 0.006
Identities = 66/395 (16%), Positives = 149/395 (37%), Gaps = 6/395 (1%)
Query: 273 SIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQEL 332
S++ ++ +L T ++ L+ E+ + ++ LE + ++
Sbjct: 2050 SVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKT 2109
Query: 333 NKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKL 392
L D + L+D +EKLQS N+ I + E L + +
Sbjct: 2110 ELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQ-IAQLNKEKELLVKES 2168
Query: 393 IEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELE 452
++ + ++S EK + + ++ + E LR+ E+ + +E + + E
Sbjct: 2169 ESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADE 2228
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEID-ELK-SKLSTEKAIKDIXXXXXXXXXXXXXXX 510
+ + + E E L +K E ++ EL+ S+ + E I D
Sbjct: 2229 KKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIE 2288
Query: 511 XXXXXXXXXRESQMKSYYEELMNLKNQITQLR-EFGAFDNL-NDVGNMINQQRDKLFELT 568
E + + E NL QI + + + D L + +++ ++ ++
Sbjct: 2289 EMARSLKVF-ELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIK 2347
Query: 569 KRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
+ + E LQ + E+ V ++ + ++ E+ + E+E + N I L +LE
Sbjct: 2348 EESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLE 2407
Query: 629 LRNEADIDVIITLAKYKKSLTLVLEKMSISNRVLK 663
+ + V+ L + + L+ ++ R L+
Sbjct: 2408 ADEKKQLCVLQQLKESEHHADLLKGRVENLERELE 2442
Score = 41.9 bits (94), Expect = 0.007
Identities = 88/491 (17%), Positives = 191/491 (38%), Gaps = 30/491 (6%)
Query: 163 QEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRT 222
+++ ++L ++KE +++ L + L + E E+ I+ L+K E L +
Sbjct: 1887 EDRDRKVESLLNEMKELDSKLHLQEVQL-MTKIEACIELEKIVGELKK---ENSDLSEKL 1942
Query: 223 KELSCALSDLNTQNAEMRKQIHSG-DHHRPYANRNXXXXXXXXXXXXXXXXSI-MKDRLS 280
+ SC +L Q E + ++S + H ++R + +++ LS
Sbjct: 1943 EYFSCDHQEL-LQRVETSEGLNSDLEMHADKSSREDIGDNVAKVNDSWKERFLDVENELS 2001
Query: 281 RAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIK 340
R + + + LEA LE ++E LE+ E+ ++ Q ++
Sbjct: 2002 RIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQ-LR 2060
Query: 341 DNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYN 400
+ A ++L + I+ + E+ L + +
Sbjct: 2061 GELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVS 2120
Query: 401 DSIEEKKTLQENIDDLRTD---LLESELRVKDLVRELD-EKESILETKQCVQKELESTKT 456
+ +++K LQE + L D L ++ +++ + +L+ EKE +++ + +Q L +
Sbjct: 2121 ELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDY 2180
Query: 457 D-------LEHRKTEIEEYKRLLFEKGEEIDELK---SKLSTE---KAIKDIXXXXXXXX 503
+ LE E E+ L EE+ +L+ KL K +
Sbjct: 2181 EKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKE 2240
Query: 504 XXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDK 563
RE QM +EL+ L + ++ + ++ +
Sbjct: 2241 RERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELD 2300
Query: 564 LFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEK-EIKMLNEKEEEHMNIINL 622
L L +E +++Q K+ ++ L + ++ + +L +KE+ EI++ +EE + +
Sbjct: 2301 LVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQI----KEESKTAVEM 2356
Query: 623 LHNKLELRNEA 633
L N+L+ NEA
Sbjct: 2357 LQNQLKELNEA 2367
Score = 39.5 bits (88), Expect = 0.040
Identities = 98/488 (20%), Positives = 188/488 (38%), Gaps = 51/488 (10%)
Query: 19 EDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKL 78
E ++E E I S I + K QEK+ EKS +E Q Q+ EL + H +
Sbjct: 2502 ERISELEIINSSFENILQEKE--QEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEA 2559
Query: 79 LGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNS 138
K S++ + +L QLLQ G + + L + V + ++ +
Sbjct: 2560 CKAKEQNLSSQ----VECLELEKAQLLQ---GLDEAKNNYIVLQSSVNGLIQEVEDGKQK 2612
Query: 139 LVDKCEETLFKRKEIINWFE--SLMSQEKGIST--KTLTMKIKEFNAENDLLKSSLDQLR 194
L K EE + +I + + S +SQ +G K ++++ E + K + Q +
Sbjct: 2613 LEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQ-KIQVLQSK 2671
Query: 195 TEFLKEINDIIDCLRKNA-NETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYA 253
L++ +++ KN NE ++ ++ + + E+++++H
Sbjct: 2672 NASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHE----MAQK 2727
Query: 254 NRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERT 313
++ + + ++ QLK +L+ +L+ + E
Sbjct: 2728 TAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGK 2787
Query: 314 VXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSAS 373
V + +++ L + N + +I REKL S
Sbjct: 2788 VREEIAEYQLRLHEAEKKHQALL--LDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDL- 2844
Query: 374 YNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQEN---IDDLRTDLLESELRVKDL 430
+K K E+N ++ +I + E KKT +N ++ L+ + ++ ++K L
Sbjct: 2845 ----LKSSKEELNNSLKATTQILE------ELKKTKMDNLKYVNQLKKENERAQGKMKLL 2894
Query: 431 VRELDEKESILETKQCVQKELESTKTDLEHRK-------------TEIEEYKRLLFEKGE 477
++ + E E K+ +QKEL + E +K TEI+E K L EK +
Sbjct: 2895 IKSCKQLE---EEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTK 2951
Query: 478 EIDELKSK 485
E DE K
Sbjct: 2952 EADEYLDK 2959
Score = 36.7 bits (81), Expect = 0.28
Identities = 64/315 (20%), Positives = 114/315 (36%), Gaps = 14/315 (4%)
Query: 277 DRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLT 336
D+L+ + QL+ N+E Q EQA S E + +
Sbjct: 440 DKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKA 499
Query: 337 QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSA---SYNKSIKDMKHEMNLNIAKLI 393
+ + L++I + Q+ + I ++ + L KL
Sbjct: 500 REVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLA 559
Query: 394 --EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKEL 451
++EK+ + S + K + +I+ L L ++E K L+ L+ K+ E + +
Sbjct: 560 VADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLF 619
Query: 452 ESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXX 511
K++ E T++E K L K I+ L++ L T++ IK
Sbjct: 620 SCWKSENEKLLTQMESEKENLQSK---INHLETCLKTQQ-IKSHEYNERVRTLEMDRENL 675
Query: 512 XXXXXXXXRESQMKSYYEELMNLKN-QITQLREFGAFDNLNDVGNMINQQRDKLFELTKR 570
KS E L ++ Q EF + ++ NM K +LT +
Sbjct: 676 SVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCL----KTSQLTGQ 731
Query: 571 QEEYDEKLQTKENEI 585
E+ + KLQ NEI
Sbjct: 732 VEDLEHKLQLLSNEI 746
Score = 36.7 bits (81), Expect = 0.28
Identities = 98/486 (20%), Positives = 181/486 (37%), Gaps = 61/486 (12%)
Query: 10 QNQTDGCLYEDLNEQESITSE-SHKITKLKTVWQEKMV-TFEKSKKELED---RQNQVME 64
Q Q + L + E I E + K + + Q + T ++ K ED QN V E
Sbjct: 842 QKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAE 901
Query: 65 LYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNK 124
++L N ++++LL KV AE + L + L +L E +LE + +
Sbjct: 902 TLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSI 961
Query: 125 VTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAEND 184
++ + ++ E L + + + ++QEK L K + F D
Sbjct: 962 ISLNKREI------------EELTQENGTLKEINASLNQEK----MNLIQKSESFANYID 1005
Query: 185 LLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIH 244
+ S+ +L ++ +E ++ + N L + K A + N++ + +
Sbjct: 1006 EREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYK----AAQEKNSKLECLLNECT 1061
Query: 245 SGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQAR 304
S NR + K L+ AE + N +++LE + R
Sbjct: 1062 S-----LCENRKNELEQLKEAFAKEHQEFLTK--LAFAEER---NQNLMLELETVQQALR 1111
Query: 305 SESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXX 364
SE + +E NK+ + + D + E+L
Sbjct: 1112 SEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVND-------LLQENEQLMKVMKTKH 1164
Query: 365 XXXXXXSASYNKSIKDMKHEMN-LNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDL--L 421
S S+K+ + E N N +++E K + ++D L L
Sbjct: 1165 ECQNLESEPIRNSVKERESERNQCNFKPQMDLEVK-----------EISLDSYNAQLVQL 1213
Query: 422 ESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE 481
E+ LR K+L + EKE K+C+Q EL++ + DLE + + + + K EID
Sbjct: 1214 EAMLRNKELKLQESEKE-----KECLQHELQTIRGDLETSNLQDMQSQEISGLKDCEIDA 1268
Query: 482 LKSKLS 487
+ +S
Sbjct: 1269 EEKYIS 1274
Score = 36.3 bits (80), Expect = 0.37
Identities = 75/451 (16%), Positives = 164/451 (36%), Gaps = 15/451 (3%)
Query: 170 KTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCAL 229
+ LT +I+E + L L ++ ++ I ++ LQ + KEL+ A+
Sbjct: 2309 ENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAV 2368
Query: 230 SDLNTQNAEMRKQIHSGDH--HRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLK 287
+ L M+ S D + RN + +L +EH
Sbjct: 2369 AALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHAD 2428
Query: 288 TNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLE 347
RV LE LE AR+ + E ++ +TQS++ +
Sbjct: 2429 LLKGRVENLERELEIARTN----QEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVV 2484
Query: 348 DIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEK- 406
I +E L + N S +++ E ++ E + ++ +
Sbjct: 2485 TIRSEKEDLTNELQKEQERISELEI-INSSFENILQEKEQEKVQMKEKSSTAMEMLQTQL 2543
Query: 407 KTLQENIDDLRTDLLESELRVKDLVRELD----EKESILETKQCVQKELESTKTDLEHRK 462
K L E + L D + + ++L +++ EK +L+ + ++ +
Sbjct: 2544 KELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLI 2603
Query: 463 TEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRES 522
E+E+ K+ L +K EEI LK+++ ++ + E
Sbjct: 2604 QEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQ 2663
Query: 523 QMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKE 582
+++ + +L++ + L+ ++ NL + + + E + + +LQ +
Sbjct: 2664 KIQVLQSKNASLQDTLEVLQ--SSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREM 2721
Query: 583 NEI-KRLVESMTEQEHVLNKKEKEIKMLNEK 612
+E+ ++ E E N+ E+++L E+
Sbjct: 2722 HEMAQKTAELQEELSGEKNRLAGELQLLLEE 2752
Score = 31.9 bits (69), Expect = 8.0
Identities = 48/257 (18%), Positives = 103/257 (40%), Gaps = 20/257 (7%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLES-ELRVKDLVRELDEKESILET--KQCV 447
K +E+K E+ ++N + R L + + + K+ EL ++ +T ++C+
Sbjct: 356 KYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECI 415
Query: 448 Q------KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS-TEKAIK--DIXXX 498
Q +EL+ K + E+++ + + ++E K KL E+A + I
Sbjct: 416 QMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKEN 475
Query: 499 XXXXXXXXXXXXXXXXXXXXXRESQMKSYYE-ELMNLKNQITQLREFGAFDNLNDVGN-- 555
++++ + E EL N+K + Q + F +
Sbjct: 476 ELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQET 535
Query: 556 MINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEE 615
M+ ++K+ Q+E L+ + + L + + +L K+E I+ LN+K +
Sbjct: 536 MLRDLQEKI-----NQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSK 590
Query: 616 HMNIINLLHNKLELRNE 632
L + LEL+ +
Sbjct: 591 TEKESKALLSALELKKK 607
>BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated, coiled-coil
containing protein kinase 1 protein.
Length = 1354
Score = 53.2 bits (122), Expect = 3e-06
Identities = 126/655 (19%), Positives = 256/655 (39%), Gaps = 59/655 (9%)
Query: 11 NQTDGCLYEDLNEQ-ESITSESHKITKLKTVWQEKMVT----FEKSKKELEDRQNQVMEL 65
+ D L E L + + + H +LK ++K T +K KEL++ NQ L
Sbjct: 418 SNADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNL 477
Query: 66 YASLRNTHRKMKLLGQKVN--LPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDN 123
+++ ++ LL ++N AE+ + + L+ K ++S L N
Sbjct: 478 ESTVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKNQLEDLKKVSQNSQLAN 537
Query: 124 KVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAEN 183
+ + K L N L+ +T + ++ +SQ + ++ +E N
Sbjct: 538 EKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLN--------RELQERN 589
Query: 184 DLLKSSLDQLRTEFLKEINDIIDCLRKNANETMA----LQLRTKELSCALSDL--NTQNA 237
+L++S Q ++ ++ I++ R++ LQ R L + L N +
Sbjct: 590 RILENSKSQTDKDYY-QLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKV 648
Query: 238 E-MRKQIHSGDHH--RPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRA----EHQLKTNV 290
E RK+ +H + N + + ++++A +HQ
Sbjct: 649 EGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEA 708
Query: 291 ERVV--QLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLED 348
+ V ++E L++ R E V D Q KL + + N +ED
Sbjct: 709 KSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKL-EHLTGNKERMED 767
Query: 349 ------IALAREKLQSXXXXXXXXXXXXSASYNKSI-KDMKHEMN--LNIAKLIEIE--- 396
+ L +E + A K + K MK E+N L +L+E E
Sbjct: 768 EVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQ 827
Query: 397 --KKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEK--ESILETKQCV-QKEL 451
K+Y + + + LQ+ ++ + + +VK+L E++EK E++ + ++ +KE
Sbjct: 828 LTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKET 887
Query: 452 ESTKTDLEHRKTEIEEYKRLL-----FEKGEEIDELKSKLSTEKAIKD--IXXXXXXXXX 504
+T+ DL K E E+ R L FE +E + S+ E KD +
Sbjct: 888 LATQLDLAETKAESEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTVSRLEEANSM 947
Query: 505 XXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFD-NLNDVGNMINQQRDK 563
E K+ E + + +I+ L+ AF+ N+N + Q +K
Sbjct: 948 LTKDIEILRRENEELTERMKKAEEEYKLEKEEEISNLK--AAFEKNINTERTLKTQAVNK 1005
Query: 564 LFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMN 618
L E+ R++ ++ + ++++ + + + LN++ ++ + K ++ +N
Sbjct: 1006 LAEIMNRKDFKIDRKKANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELN 1060
Score = 38.7 bits (86), Expect = 0.070
Identities = 65/319 (20%), Positives = 136/319 (42%), Gaps = 29/319 (9%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLR---TDLLESELRVKDLVR 432
+ +K + L KL +++K+ ++ + +T + LR T++ +S +++ L R
Sbjct: 524 EDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNR 583
Query: 433 ELDEKESILETKQC--------VQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKS 484
EL E+ ILE + +Q LE+ + D H I + + + EE+ LK
Sbjct: 584 ELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKH 643
Query: 485 KLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREF 544
L EK ++ + ++ E+ +N ++++T+ R
Sbjct: 644 NL--EK-VEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVN-EHKVTKARLT 699
Query: 545 GAFDNLNDVGNM-INQQRDKLFELTKRQEEYDEKLQTKENEIKR----LVESMTEQEHVL 599
++ + ++ + + KL E + +E+ + ++ E + L +S + EH+
Sbjct: 700 DKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLT 759
Query: 600 NKKEK---EIKMLNEKEEEHMNIINLLHNKLELRN-EADIDVIITLAKYKKSLTLVLEKM 655
KE+ E+K L + E+ N LL N+L+ + EAD L +K + + +
Sbjct: 760 GNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEAD-----NLKGLEKQMKQEINTL 814
Query: 656 SISNRVLKCSLLGVVTQSR 674
+ R+L+ L + Q R
Sbjct: 815 LEAKRLLEFELAQLTKQYR 833
Score = 38.3 bits (85), Expect = 0.092
Identities = 50/262 (19%), Positives = 113/262 (43%), Gaps = 19/262 (7%)
Query: 414 DDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLF 473
D++ S +++ +++ELDE+ + + ++E K L+HR I EY+R
Sbjct: 447 DEMEQKCRTSNIKLDKIMKELDEEGNQRRNLESTVSQIEKEKMLLQHR---INEYQRKAE 503
Query: 474 EKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMN 533
++ E+ +++++ST K + +++ + +
Sbjct: 504 QENEKRRNVENEVSTLKNQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVR 563
Query: 534 LKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYD-----EKLQTKENEIKRL 588
L+ T++ + + L + + Q+R+++ E +K Q + D L+ + +
Sbjct: 564 LRKSHTEMSK--SISQLESLNREL-QERNRILENSKSQTDKDYYQLQAILEAERRDRGHD 620
Query: 589 VESMTEQEHVLNKKEKEIKMLN---EK-EEEHMNIINLLHNKLELRNEADIDVIITLAKY 644
E + + + + ++E+K L EK E E ++L++ + +N +ID+ L
Sbjct: 621 SEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKL--- 677
Query: 645 KKSLTLVLEKMSISNRVLKCSL 666
KSL LE+ ++V K L
Sbjct: 678 -KSLQQRLEQEVNEHKVTKARL 698
>AL445666-1|CAH71810.1| 3114|Homo sapiens centromere protein F,
350/400ka (mitosin) protein.
Length = 3114
Score = 53.2 bits (122), Expect = 3e-06
Identities = 66/357 (18%), Positives = 132/357 (36%), Gaps = 10/357 (2%)
Query: 278 RLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQ 337
RL E ++K V + +L+ LE+A+ E E+ + +DQ K T
Sbjct: 300 RLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTA 359
Query: 338 SIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEK 397
+ ED++ R+ +S + + + + + I+++
Sbjct: 360 LEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKA 419
Query: 398 KYNDSIEEKK----TLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELES 453
+ +++ K LQ +D L + + E +++ ++L E + Q + EL
Sbjct: 420 RLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENEL-- 477
Query: 454 TKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXX 513
+ +E K E K +K E+ L+++L K +
Sbjct: 478 -RRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETM 536
Query: 514 XXXXXXRESQMKSYYEELMNLKNQITQLREFG--AFDNLNDVGNMINQQRDKLFELTKRQ 571
+ +Q ++ L LK + L + + D L + I Q DKL + K
Sbjct: 537 LRDLQEKINQQENSL-TLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKES 595
Query: 572 EEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
+ L+ K+ E + L E T ++ EK + + ++E + IN L L+
Sbjct: 596 KALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLK 652
Score = 44.4 bits (100), Expect = 0.001
Identities = 143/660 (21%), Positives = 258/660 (39%), Gaps = 64/660 (9%)
Query: 30 ESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAE 89
ESH+ L + + EK++ L+ + V EL + K++ L + S
Sbjct: 1992 ESHQSECLHCIQVAEAEVKEKTEL-LQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLT 2050
Query: 90 ELHIMN-VAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCE---- 144
+ + N +A+L+ E+ L L E S D + +V+K L +LV+K E
Sbjct: 2051 KCELENQIAQLNKEKEL-LVKESESLQARLSESDYE-KLNVSKALEA--ALVEKGEFALR 2106
Query: 145 --ETLFKRKEIINWFESLMSQEKGISTKTLTM--KIKEFNAENDLLKSSLDQLRTEF-LK 199
T + ++ E L + + K L + K+KE END LK ++ L E +
Sbjct: 2107 LSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMS 2166
Query: 200 EIND---IIDCLRKNAN-ETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANR 255
E N I+D A ET+ Q+ S + +L+ K+ + +
Sbjct: 2167 EENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKE------NLTKQIQ 2220
Query: 256 NXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQ-LEAALEQARSESWSLERTV 314
S+++++ +AE Q+K + V+ L+ L++ +L
Sbjct: 2221 EKQGQLSELDKLLSSFKSLLEEK-EQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQ 2279
Query: 315 XXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASY 374
++E ++L SI+ LE A EK Q +
Sbjct: 2280 EIMKATEQSLDPPIEEE-HQLRNSIEKLRARLE----ADEKKQLCVLQQLKESEHHADLL 2334
Query: 375 NKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVREL 434
+++++ E+ + + +S E +TL+ I+ + L EL D+V
Sbjct: 2335 KGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLEL---DVVTIR 2391
Query: 435 DEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKD 494
EKE++ +QKE E ++LE + E +L EK +E ++K K ST +
Sbjct: 2392 SEKENLTNE---LQKEQERI-SELEIINSSFEN---ILQEKEQEKVQMKEKSSTAM---E 2441
Query: 495 IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVG 554
+ +E + S E L K Q+ Q L++
Sbjct: 2442 MLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQ--------GLDEAK 2493
Query: 555 NMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNK---KEKEIKMLNE 611
N + + L + E+ +KL+ K+ EI RL + +QE +++K E E ++ E
Sbjct: 2494 NNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKE 2553
Query: 612 KEEEHMNIINLLHNKLEL---RNEADIDVIITLAKYKKSLTLVLE-----KMSISNRVLK 663
+ E N+ L K+++ +N + D + L K+L LE KMS +V K
Sbjct: 2554 QNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNK 2613
Score = 42.7 bits (96), Expect = 0.004
Identities = 91/479 (18%), Positives = 194/479 (40%), Gaps = 33/479 (6%)
Query: 28 TSESHKITKLKTVWQEKMVTFEKSKKELEDR-QNQVMELYASLRNTHRKMKLLGQKVNLP 86
+S H + +LK QE ELE R Q E+ + N ++++L +K +
Sbjct: 274 SSSPHLLDQLKAQNQE----LRNKINELELRLQGHEKEMKGQV-NKFQELQLQLEKAKVE 328
Query: 87 SAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKL-LNIPNSLVDKCE- 144
E+ ++N + ++L++ A + + +++ L+ K+ L N+ +C
Sbjct: 329 LIEKEKVLNKCR---DELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSL 385
Query: 145 ETLFKRKEIINWFESLMSQEKGIST---------KTLTMKIKEFNAENDLLKSSLDQLRT 195
E K KE + E L Q++ T LT ++++ +++L++ LD+L +
Sbjct: 386 EQKIKEKEK-EFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTS 444
Query: 196 EFLKEINDIIDCLRKNANETMALQ---LRTKELSCALSDLNTQNAEMRKQIHSGDHHRPY 252
+ N++ + +K A Q ++ EL ++ ++ +N ++ HS R
Sbjct: 445 VKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKS--HSEQKAREV 502
Query: 253 ANRNXXXXXXXX-XXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAAL--EQARSESWS 309
+ MK + + E L+ E++ Q E +L E+ +
Sbjct: 503 CHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVAD 562
Query: 310 LERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXX 369
LE+ +Q +KL+++ K++ L + L +++ +
Sbjct: 563 LEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCW 622
Query: 370 XSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKD 429
S + K + M+ E +K+ +E + E + L D + +++
Sbjct: 623 KSEN-EKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRN 681
Query: 430 LVRELDEKESILETKQCVQKELESTK--TDLEHRKTEIEEYKRLLFEKGEEIDELKSKL 486
L LD K +ET++ EL+ +D +H+K EIE + ++++L+ KL
Sbjct: 682 LHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQK-EIENMCLKTSQLTGQVEDLEHKL 739
Score = 42.3 bits (95), Expect = 0.006
Identities = 66/395 (16%), Positives = 149/395 (37%), Gaps = 6/395 (1%)
Query: 273 SIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQEL 332
S++ ++ +L T ++ L+ E+ + ++ LE + ++
Sbjct: 1954 SVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKT 2013
Query: 333 NKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKL 392
L D + L+D +EKLQS N+ I + E L + +
Sbjct: 2014 ELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQ-IAQLNKEKELLVKES 2072
Query: 393 IEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELE 452
++ + ++S EK + + ++ + E LR+ E+ + +E + + E
Sbjct: 2073 ESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADE 2132
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEID-ELK-SKLSTEKAIKDIXXXXXXXXXXXXXXX 510
+ + + E E L +K E ++ EL+ S+ + E I D
Sbjct: 2133 KKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIE 2192
Query: 511 XXXXXXXXXRESQMKSYYEELMNLKNQITQLR-EFGAFDNL-NDVGNMINQQRDKLFELT 568
E + + E NL QI + + + D L + +++ ++ ++
Sbjct: 2193 EMARSLKVF-ELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIK 2251
Query: 569 KRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
+ + E LQ + E+ V ++ + ++ E+ + E+E + N I L +LE
Sbjct: 2252 EESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLE 2311
Query: 629 LRNEADIDVIITLAKYKKSLTLVLEKMSISNRVLK 663
+ + V+ L + + L+ ++ R L+
Sbjct: 2312 ADEKKQLCVLQQLKESEHHADLLKGRVENLERELE 2346
Score = 41.9 bits (94), Expect = 0.007
Identities = 88/491 (17%), Positives = 191/491 (38%), Gaps = 30/491 (6%)
Query: 163 QEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRT 222
+++ ++L ++KE +++ L + L + E E+ I+ L+K E L +
Sbjct: 1791 EDRDRKVESLLNEMKELDSKLHLQEVQL-MTKIEACIELEKIVGELKK---ENSDLSEKL 1846
Query: 223 KELSCALSDLNTQNAEMRKQIHSG-DHHRPYANRNXXXXXXXXXXXXXXXXSI-MKDRLS 280
+ SC +L Q E + ++S + H ++R + +++ LS
Sbjct: 1847 EYFSCDHQEL-LQRVETSEGLNSDLEMHADKSSREDIGDNVAKVNDSWKERFLDVENELS 1905
Query: 281 RAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIK 340
R + + + LEA LE ++E LE+ E+ ++ Q ++
Sbjct: 1906 RIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQ-LR 1964
Query: 341 DNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYN 400
+ A ++L + I+ + E+ L + +
Sbjct: 1965 GELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVS 2024
Query: 401 DSIEEKKTLQENIDDLRTD---LLESELRVKDLVRELD-EKESILETKQCVQKELESTKT 456
+ +++K LQE + L D L ++ +++ + +L+ EKE +++ + +Q L +
Sbjct: 2025 ELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDY 2084
Query: 457 D-------LEHRKTEIEEYKRLLFEKGEEIDELK---SKLSTE---KAIKDIXXXXXXXX 503
+ LE E E+ L EE+ +L+ KL K +
Sbjct: 2085 EKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKE 2144
Query: 504 XXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDK 563
RE QM +EL+ L + ++ + ++ +
Sbjct: 2145 RERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELD 2204
Query: 564 LFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEK-EIKMLNEKEEEHMNIINL 622
L L +E +++Q K+ ++ L + ++ + +L +KE+ EI++ +EE + +
Sbjct: 2205 LVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQI----KEESKTAVEM 2260
Query: 623 LHNKLELRNEA 633
L N+L+ NEA
Sbjct: 2261 LQNQLKELNEA 2271
Score = 39.5 bits (88), Expect = 0.040
Identities = 98/488 (20%), Positives = 188/488 (38%), Gaps = 51/488 (10%)
Query: 19 EDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKL 78
E ++E E I S I + K QEK+ EKS +E Q Q+ EL + H +
Sbjct: 2406 ERISELEIINSSFENILQEKE--QEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEA 2463
Query: 79 LGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNS 138
K S++ + +L QLLQ G + + L + V + ++ +
Sbjct: 2464 CKAKEQNLSSQ----VECLELEKAQLLQ---GLDEAKNNYIVLQSSVNGLIQEVEDGKQK 2516
Query: 139 LVDKCEETLFKRKEIINWFE--SLMSQEKGIST--KTLTMKIKEFNAENDLLKSSLDQLR 194
L K EE + +I + + S +SQ +G K ++++ E + K + Q +
Sbjct: 2517 LEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQ-KIQVLQSK 2575
Query: 195 TEFLKEINDIIDCLRKNA-NETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYA 253
L++ +++ KN NE ++ ++ + + E+++++H
Sbjct: 2576 NASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHE----MAQK 2631
Query: 254 NRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERT 313
++ + + ++ QLK +L+ +L+ + E
Sbjct: 2632 TAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGK 2691
Query: 314 VXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSAS 373
V + +++ L + N + +I REKL S
Sbjct: 2692 VREEIAEYQLRLHEAEKKHQALL--LDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDL- 2748
Query: 374 YNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQEN---IDDLRTDLLESELRVKDL 430
+K K E+N ++ +I + E KKT +N ++ L+ + ++ ++K L
Sbjct: 2749 ----LKSSKEELNNSLKATTQILE------ELKKTKMDNLKYVNQLKKENERAQGKMKLL 2798
Query: 431 VRELDEKESILETKQCVQKELESTKTDLEHRK-------------TEIEEYKRLLFEKGE 477
++ + E E K+ +QKEL + E +K TEI+E K L EK +
Sbjct: 2799 IKSCKQLE---EEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTK 2855
Query: 478 EIDELKSK 485
E DE K
Sbjct: 2856 EADEYLDK 2863
Score = 36.7 bits (81), Expect = 0.28
Identities = 64/315 (20%), Positives = 114/315 (36%), Gaps = 14/315 (4%)
Query: 277 DRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLT 336
D+L+ + QL+ N+E Q EQA S E + +
Sbjct: 440 DKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKA 499
Query: 337 QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSA---SYNKSIKDMKHEMNLNIAKLI 393
+ + L++I + Q+ + I ++ + L KL
Sbjct: 500 REVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLA 559
Query: 394 --EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKEL 451
++EK+ + S + K + +I+ L L ++E K L+ L+ K+ E + +
Sbjct: 560 VADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLF 619
Query: 452 ESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXX 511
K++ E T++E K L K I+ L++ L T++ IK
Sbjct: 620 SCWKSENEKLLTQMESEKENLQSK---INHLETCLKTQQ-IKSHEYNERVRTLEMDRENL 675
Query: 512 XXXXXXXXRESQMKSYYEELMNLKN-QITQLREFGAFDNLNDVGNMINQQRDKLFELTKR 570
KS E L ++ Q EF + ++ NM K +LT +
Sbjct: 676 SVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCL----KTSQLTGQ 731
Query: 571 QEEYDEKLQTKENEI 585
E+ + KLQ NEI
Sbjct: 732 VEDLEHKLQLLSNEI 746
Score = 36.7 bits (81), Expect = 0.28
Identities = 98/486 (20%), Positives = 181/486 (37%), Gaps = 61/486 (12%)
Query: 10 QNQTDGCLYEDLNEQESITSE-SHKITKLKTVWQEKMV-TFEKSKKELED---RQNQVME 64
Q Q + L + E I E + K + + Q + T ++ K ED QN V E
Sbjct: 842 QKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAE 901
Query: 65 LYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNK 124
++L N ++++LL KV AE + L + L +L E +LE + +
Sbjct: 902 TLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSI 961
Query: 125 VTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAEND 184
++ + ++ E L + + + ++QEK L K + F D
Sbjct: 962 ISLNKREI------------EELTQENGTLKEINASLNQEK----MNLIQKSESFANYID 1005
Query: 185 LLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIH 244
+ S+ +L ++ +E ++ + N L + K A + N++ + +
Sbjct: 1006 EREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYK----AAQEKNSKLECLLNECT 1061
Query: 245 SGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQAR 304
S NR + K L+ AE + N +++LE + R
Sbjct: 1062 S-----LCENRKNELEQLKEAFAKEHQEFLTK--LAFAEER---NQNLMLELETVQQALR 1111
Query: 305 SESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXX 364
SE + +E NK+ + + D + E+L
Sbjct: 1112 SEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVND-------LLQENEQLMKVMKTKH 1164
Query: 365 XXXXXXSASYNKSIKDMKHEMN-LNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDL--L 421
S S+K+ + E N N +++E K + ++D L L
Sbjct: 1165 ECQNLESEPIRNSVKERESERNQCNFKPQMDLEVK-----------EISLDSYNAQLVQL 1213
Query: 422 ESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE 481
E+ LR K+L + EKE K+C+Q EL++ + DLE + + + + K EID
Sbjct: 1214 EAMLRNKELKLQESEKE-----KECLQHELQTIRGDLETSNLQDMQSQEISGLKDCEIDA 1268
Query: 482 LKSKLS 487
+ +S
Sbjct: 1269 EEKYIS 1274
Score = 36.7 bits (81), Expect = 0.28
Identities = 75/451 (16%), Positives = 164/451 (36%), Gaps = 15/451 (3%)
Query: 170 KTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCAL 229
+ LT +I+E + L L ++ ++ I ++ LQ + KEL+ A+
Sbjct: 2213 ENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAV 2272
Query: 230 SDLNTQNAEMRKQIHSGDH--HRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLK 287
+ L M+ S D + RN + +L +EH
Sbjct: 2273 AALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHAD 2332
Query: 288 TNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLE 347
RV LE LE AR+ + E ++ +TQS++ +
Sbjct: 2333 LLKGRVENLERELEIARTN----QEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVV 2388
Query: 348 DIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEK- 406
I +E L + N S +++ E ++ E + ++ +
Sbjct: 2389 TIRSEKENLTNELQKEQERISELEI-INSSFENILQEKEQEKVQMKEKSSTAMEMLQTQL 2447
Query: 407 KTLQENIDDLRTDLLESELRVKDLVRELD----EKESILETKQCVQKELESTKTDLEHRK 462
K L E + L D + + ++L +++ EK +L+ + ++ +
Sbjct: 2448 KELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLI 2507
Query: 463 TEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRES 522
E+E+ K+ L +K EEI LK+++ ++ + E
Sbjct: 2508 QEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQ 2567
Query: 523 QMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKE 582
+++ + +L++ + L+ ++ NL + + + E + + +LQ +
Sbjct: 2568 KIQVLQSKNASLQDTLEVLQ--SSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREM 2625
Query: 583 NEI-KRLVESMTEQEHVLNKKEKEIKMLNEK 612
+E+ ++ E E N+ E+++L E+
Sbjct: 2626 HEMAQKTAELQEELSGEKNRLAGELQLLLEE 2656
Score = 31.9 bits (69), Expect = 8.0
Identities = 48/257 (18%), Positives = 103/257 (40%), Gaps = 20/257 (7%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLES-ELRVKDLVRELDEKESILET--KQCV 447
K +E+K E+ ++N + R L + + + K+ EL ++ +T ++C+
Sbjct: 356 KYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECI 415
Query: 448 Q------KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS-TEKAIK--DIXXX 498
Q +EL+ K + E+++ + + ++E K KL E+A + I
Sbjct: 416 QMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKEN 475
Query: 499 XXXXXXXXXXXXXXXXXXXXXRESQMKSYYE-ELMNLKNQITQLREFGAFDNLNDVGN-- 555
++++ + E EL N+K + Q + F +
Sbjct: 476 ELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQET 535
Query: 556 MINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEE 615
M+ ++K+ Q+E L+ + + L + + +L K+E I+ LN+K +
Sbjct: 536 MLRDLQEKI-----NQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSK 590
Query: 616 HMNIINLLHNKLELRNE 632
L + LEL+ +
Sbjct: 591 TEKESKALLSALELKKK 607
>AL445305-6|CAH73032.1| 3114|Homo sapiens centromere protein F,
350/400ka (mitosin) protein.
Length = 3114
Score = 53.2 bits (122), Expect = 3e-06
Identities = 66/357 (18%), Positives = 132/357 (36%), Gaps = 10/357 (2%)
Query: 278 RLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQ 337
RL E ++K V + +L+ LE+A+ E E+ + +DQ K T
Sbjct: 300 RLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTA 359
Query: 338 SIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEK 397
+ ED++ R+ +S + + + + + I+++
Sbjct: 360 LEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKA 419
Query: 398 KYNDSIEEKK----TLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELES 453
+ +++ K LQ +D L + + E +++ ++L E + Q + EL
Sbjct: 420 RLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENEL-- 477
Query: 454 TKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXX 513
+ +E K E K +K E+ L+++L K +
Sbjct: 478 -RRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETM 536
Query: 514 XXXXXXRESQMKSYYEELMNLKNQITQLREFG--AFDNLNDVGNMINQQRDKLFELTKRQ 571
+ +Q ++ L LK + L + + D L + I Q DKL + K
Sbjct: 537 LRDLQEKINQQENSL-TLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKES 595
Query: 572 EEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
+ L+ K+ E + L E T ++ EK + + ++E + IN L L+
Sbjct: 596 KALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLK 652
Score = 44.4 bits (100), Expect = 0.001
Identities = 143/660 (21%), Positives = 258/660 (39%), Gaps = 64/660 (9%)
Query: 30 ESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAE 89
ESH+ L + + EK++ L+ + V EL + K++ L + S
Sbjct: 1992 ESHQSECLHCIQVAEAEVKEKTEL-LQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLT 2050
Query: 90 ELHIMN-VAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCE---- 144
+ + N +A+L+ E+ L L E S D + +V+K L +LV+K E
Sbjct: 2051 KCELENQIAQLNKEKEL-LVKESESLQARLSESDYE-KLNVSKALEA--ALVEKGEFALR 2106
Query: 145 --ETLFKRKEIINWFESLMSQEKGISTKTLTM--KIKEFNAENDLLKSSLDQLRTEF-LK 199
T + ++ E L + + K L + K+KE END LK ++ L E +
Sbjct: 2107 LSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMS 2166
Query: 200 EIND---IIDCLRKNAN-ETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANR 255
E N I+D A ET+ Q+ S + +L+ K+ + +
Sbjct: 2167 EENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKE------NLTKQIQ 2220
Query: 256 NXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQ-LEAALEQARSESWSLERTV 314
S+++++ +AE Q+K + V+ L+ L++ +L
Sbjct: 2221 EKQGQLSELDKLLSSFKSLLEEK-EQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQ 2279
Query: 315 XXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASY 374
++E ++L SI+ LE A EK Q +
Sbjct: 2280 EIMKATEQSLDPPIEEE-HQLRNSIEKLRARLE----ADEKKQLCVLQQLKESEHHADLL 2334
Query: 375 NKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVREL 434
+++++ E+ + + +S E +TL+ I+ + L EL D+V
Sbjct: 2335 KGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLEL---DVVTIR 2391
Query: 435 DEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKD 494
EKE++ +QKE E ++LE + E +L EK +E ++K K ST +
Sbjct: 2392 SEKENLTNE---LQKEQERI-SELEIINSSFEN---ILQEKEQEKVQMKEKSSTAM---E 2441
Query: 495 IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVG 554
+ +E + S E L K Q+ Q L++
Sbjct: 2442 MLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQ--------GLDEAK 2493
Query: 555 NMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNK---KEKEIKMLNE 611
N + + L + E+ +KL+ K+ EI RL + +QE +++K E E ++ E
Sbjct: 2494 NNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKE 2553
Query: 612 KEEEHMNIINLLHNKLEL---RNEADIDVIITLAKYKKSLTLVLE-----KMSISNRVLK 663
+ E N+ L K+++ +N + D + L K+L LE KMS +V K
Sbjct: 2554 QNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNK 2613
Score = 42.7 bits (96), Expect = 0.004
Identities = 91/479 (18%), Positives = 194/479 (40%), Gaps = 33/479 (6%)
Query: 28 TSESHKITKLKTVWQEKMVTFEKSKKELEDR-QNQVMELYASLRNTHRKMKLLGQKVNLP 86
+S H + +LK QE ELE R Q E+ + N ++++L +K +
Sbjct: 274 SSSPHLLDQLKAQNQE----LRNKINELELRLQGHEKEMKGQV-NKFQELQLQLEKAKVE 328
Query: 87 SAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKL-LNIPNSLVDKCE- 144
E+ ++N + ++L++ A + + +++ L+ K+ L N+ +C
Sbjct: 329 LIEKEKVLNKCR---DELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSL 385
Query: 145 ETLFKRKEIINWFESLMSQEKGIST---------KTLTMKIKEFNAENDLLKSSLDQLRT 195
E K KE + E L Q++ T LT ++++ +++L++ LD+L +
Sbjct: 386 EQKIKEKEK-EFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTS 444
Query: 196 EFLKEINDIIDCLRKNANETMALQ---LRTKELSCALSDLNTQNAEMRKQIHSGDHHRPY 252
+ N++ + +K A Q ++ EL ++ ++ +N ++ HS R
Sbjct: 445 VKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKS--HSEQKAREV 502
Query: 253 ANRNXXXXXXXX-XXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAAL--EQARSESWS 309
+ MK + + E L+ E++ Q E +L E+ +
Sbjct: 503 CHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVAD 562
Query: 310 LERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXX 369
LE+ +Q +KL+++ K++ L + L +++ +
Sbjct: 563 LEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCW 622
Query: 370 XSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKD 429
S + K + M+ E +K+ +E + E + L D + +++
Sbjct: 623 KSEN-EKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRN 681
Query: 430 LVRELDEKESILETKQCVQKELESTK--TDLEHRKTEIEEYKRLLFEKGEEIDELKSKL 486
L LD K +ET++ EL+ +D +H+K EIE + ++++L+ KL
Sbjct: 682 LHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQK-EIENMCLKTSQLTGQVEDLEHKL 739
Score = 42.3 bits (95), Expect = 0.006
Identities = 66/395 (16%), Positives = 149/395 (37%), Gaps = 6/395 (1%)
Query: 273 SIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQEL 332
S++ ++ +L T ++ L+ E+ + ++ LE + ++
Sbjct: 1954 SVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKT 2013
Query: 333 NKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKL 392
L D + L+D +EKLQS N+ I + E L + +
Sbjct: 2014 ELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQ-IAQLNKEKELLVKES 2072
Query: 393 IEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELE 452
++ + ++S EK + + ++ + E LR+ E+ + +E + + E
Sbjct: 2073 ESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADE 2132
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEID-ELK-SKLSTEKAIKDIXXXXXXXXXXXXXXX 510
+ + + E E L +K E ++ EL+ S+ + E I D
Sbjct: 2133 KKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIE 2192
Query: 511 XXXXXXXXXRESQMKSYYEELMNLKNQITQLR-EFGAFDNL-NDVGNMINQQRDKLFELT 568
E + + E NL QI + + + D L + +++ ++ ++
Sbjct: 2193 EMARSLKVF-ELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIK 2251
Query: 569 KRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
+ + E LQ + E+ V ++ + ++ E+ + E+E + N I L +LE
Sbjct: 2252 EESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLE 2311
Query: 629 LRNEADIDVIITLAKYKKSLTLVLEKMSISNRVLK 663
+ + V+ L + + L+ ++ R L+
Sbjct: 2312 ADEKKQLCVLQQLKESEHHADLLKGRVENLERELE 2346
Score = 41.9 bits (94), Expect = 0.007
Identities = 88/491 (17%), Positives = 191/491 (38%), Gaps = 30/491 (6%)
Query: 163 QEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRT 222
+++ ++L ++KE +++ L + L + E E+ I+ L+K E L +
Sbjct: 1791 EDRDRKVESLLNEMKELDSKLHLQEVQL-MTKIEACIELEKIVGELKK---ENSDLSEKL 1846
Query: 223 KELSCALSDLNTQNAEMRKQIHSG-DHHRPYANRNXXXXXXXXXXXXXXXXSI-MKDRLS 280
+ SC +L Q E + ++S + H ++R + +++ LS
Sbjct: 1847 EYFSCDHQEL-LQRVETSEGLNSDLEMHADKSSREDIGDNVAKVNDSWKERFLDVENELS 1905
Query: 281 RAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIK 340
R + + + LEA LE ++E LE+ E+ ++ Q ++
Sbjct: 1906 RIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQ-LR 1964
Query: 341 DNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYN 400
+ A ++L + I+ + E+ L + +
Sbjct: 1965 GELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVS 2024
Query: 401 DSIEEKKTLQENIDDLRTD---LLESELRVKDLVRELD-EKESILETKQCVQKELESTKT 456
+ +++K LQE + L D L ++ +++ + +L+ EKE +++ + +Q L +
Sbjct: 2025 ELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDY 2084
Query: 457 D-------LEHRKTEIEEYKRLLFEKGEEIDELK---SKLSTE---KAIKDIXXXXXXXX 503
+ LE E E+ L EE+ +L+ KL K +
Sbjct: 2085 EKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKE 2144
Query: 504 XXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDK 563
RE QM +EL+ L + ++ + ++ +
Sbjct: 2145 RERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELD 2204
Query: 564 LFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEK-EIKMLNEKEEEHMNIINL 622
L L +E +++Q K+ ++ L + ++ + +L +KE+ EI++ +EE + +
Sbjct: 2205 LVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQI----KEESKTAVEM 2260
Query: 623 LHNKLELRNEA 633
L N+L+ NEA
Sbjct: 2261 LQNQLKELNEA 2271
Score = 39.5 bits (88), Expect = 0.040
Identities = 98/488 (20%), Positives = 188/488 (38%), Gaps = 51/488 (10%)
Query: 19 EDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKL 78
E ++E E I S I + K QEK+ EKS +E Q Q+ EL + H +
Sbjct: 2406 ERISELEIINSSFENILQEKE--QEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEA 2463
Query: 79 LGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNS 138
K S++ + +L QLLQ G + + L + V + ++ +
Sbjct: 2464 CKAKEQNLSSQ----VECLELEKAQLLQ---GLDEAKNNYIVLQSSVNGLIQEVEDGKQK 2516
Query: 139 LVDKCEETLFKRKEIINWFE--SLMSQEKGIST--KTLTMKIKEFNAENDLLKSSLDQLR 194
L K EE + +I + + S +SQ +G K ++++ E + K + Q +
Sbjct: 2517 LEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQ-KIQVLQSK 2575
Query: 195 TEFLKEINDIIDCLRKNA-NETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYA 253
L++ +++ KN NE ++ ++ + + E+++++H
Sbjct: 2576 NASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHE----MAQK 2631
Query: 254 NRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERT 313
++ + + ++ QLK +L+ +L+ + E
Sbjct: 2632 TAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGK 2691
Query: 314 VXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSAS 373
V + +++ L + N + +I REKL S
Sbjct: 2692 VREEIAEYQLRLHEAEKKHQALL--LDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDL- 2748
Query: 374 YNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQEN---IDDLRTDLLESELRVKDL 430
+K K E+N ++ +I + E KKT +N ++ L+ + ++ ++K L
Sbjct: 2749 ----LKSSKEELNNSLKATTQILE------ELKKTKMDNLKYVNQLKKENERAQGKMKLL 2798
Query: 431 VRELDEKESILETKQCVQKELESTKTDLEHRK-------------TEIEEYKRLLFEKGE 477
++ + E E K+ +QKEL + E +K TEI+E K L EK +
Sbjct: 2799 IKSCKQLE---EEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTK 2855
Query: 478 EIDELKSK 485
E DE K
Sbjct: 2856 EADEYLDK 2863
Score = 36.7 bits (81), Expect = 0.28
Identities = 64/315 (20%), Positives = 114/315 (36%), Gaps = 14/315 (4%)
Query: 277 DRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLT 336
D+L+ + QL+ N+E Q EQA S E + +
Sbjct: 440 DKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKA 499
Query: 337 QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSA---SYNKSIKDMKHEMNLNIAKLI 393
+ + L++I + Q+ + I ++ + L KL
Sbjct: 500 REVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLA 559
Query: 394 --EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKEL 451
++EK+ + S + K + +I+ L L ++E K L+ L+ K+ E + +
Sbjct: 560 VADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLF 619
Query: 452 ESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXX 511
K++ E T++E K L K I+ L++ L T++ IK
Sbjct: 620 SCWKSENEKLLTQMESEKENLQSK---INHLETCLKTQQ-IKSHEYNERVRTLEMDRENL 675
Query: 512 XXXXXXXXRESQMKSYYEELMNLKN-QITQLREFGAFDNLNDVGNMINQQRDKLFELTKR 570
KS E L ++ Q EF + ++ NM K +LT +
Sbjct: 676 SVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCL----KTSQLTGQ 731
Query: 571 QEEYDEKLQTKENEI 585
E+ + KLQ NEI
Sbjct: 732 VEDLEHKLQLLSNEI 746
Score = 36.7 bits (81), Expect = 0.28
Identities = 98/486 (20%), Positives = 181/486 (37%), Gaps = 61/486 (12%)
Query: 10 QNQTDGCLYEDLNEQESITSE-SHKITKLKTVWQEKMV-TFEKSKKELED---RQNQVME 64
Q Q + L + E I E + K + + Q + T ++ K ED QN V E
Sbjct: 842 QKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAE 901
Query: 65 LYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNK 124
++L N ++++LL KV AE + L + L +L E +LE + +
Sbjct: 902 TLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSI 961
Query: 125 VTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAEND 184
++ + ++ E L + + + ++QEK L K + F D
Sbjct: 962 ISLNKREI------------EELTQENGTLKEINASLNQEK----MNLIQKSESFANYID 1005
Query: 185 LLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIH 244
+ S+ +L ++ +E ++ + N L + K A + N++ + +
Sbjct: 1006 EREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYK----AAQEKNSKLECLLNECT 1061
Query: 245 SGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQAR 304
S NR + K L+ AE + N +++LE + R
Sbjct: 1062 S-----LCENRKNELEQLKEAFAKEHQEFLTK--LAFAEER---NQNLMLELETVQQALR 1111
Query: 305 SESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXX 364
SE + +E NK+ + + D + E+L
Sbjct: 1112 SEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVND-------LLQENEQLMKVMKTKH 1164
Query: 365 XXXXXXSASYNKSIKDMKHEMN-LNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDL--L 421
S S+K+ + E N N +++E K + ++D L L
Sbjct: 1165 ECQNLESEPIRNSVKERESERNQCNFKPQMDLEVK-----------EISLDSYNAQLVQL 1213
Query: 422 ESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE 481
E+ LR K+L + EKE K+C+Q EL++ + DLE + + + + K EID
Sbjct: 1214 EAMLRNKELKLQESEKE-----KECLQHELQTIRGDLETSNLQDMQSQEISGLKDCEIDA 1268
Query: 482 LKSKLS 487
+ +S
Sbjct: 1269 EEKYIS 1274
Score = 36.7 bits (81), Expect = 0.28
Identities = 75/451 (16%), Positives = 164/451 (36%), Gaps = 15/451 (3%)
Query: 170 KTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCAL 229
+ LT +I+E + L L ++ ++ I ++ LQ + KEL+ A+
Sbjct: 2213 ENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAV 2272
Query: 230 SDLNTQNAEMRKQIHSGDH--HRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLK 287
+ L M+ S D + RN + +L +EH
Sbjct: 2273 AALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHAD 2332
Query: 288 TNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLE 347
RV LE LE AR+ + E ++ +TQS++ +
Sbjct: 2333 LLKGRVENLERELEIARTN----QEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVV 2388
Query: 348 DIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEK- 406
I +E L + N S +++ E ++ E + ++ +
Sbjct: 2389 TIRSEKENLTNELQKEQERISELEI-INSSFENILQEKEQEKVQMKEKSSTAMEMLQTQL 2447
Query: 407 KTLQENIDDLRTDLLESELRVKDLVRELD----EKESILETKQCVQKELESTKTDLEHRK 462
K L E + L D + + ++L +++ EK +L+ + ++ +
Sbjct: 2448 KELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLI 2507
Query: 463 TEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRES 522
E+E+ K+ L +K EEI LK+++ ++ + E
Sbjct: 2508 QEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQ 2567
Query: 523 QMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKE 582
+++ + +L++ + L+ ++ NL + + + E + + +LQ +
Sbjct: 2568 KIQVLQSKNASLQDTLEVLQ--SSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREM 2625
Query: 583 NEI-KRLVESMTEQEHVLNKKEKEIKMLNEK 612
+E+ ++ E E N+ E+++L E+
Sbjct: 2626 HEMAQKTAELQEELSGEKNRLAGELQLLLEE 2656
Score = 31.9 bits (69), Expect = 8.0
Identities = 48/257 (18%), Positives = 103/257 (40%), Gaps = 20/257 (7%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLES-ELRVKDLVRELDEKESILET--KQCV 447
K +E+K E+ ++N + R L + + + K+ EL ++ +T ++C+
Sbjct: 356 KYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECI 415
Query: 448 Q------KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS-TEKAIK--DIXXX 498
Q +EL+ K + E+++ + + ++E K KL E+A + I
Sbjct: 416 QMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKEN 475
Query: 499 XXXXXXXXXXXXXXXXXXXXXRESQMKSYYE-ELMNLKNQITQLREFGAFDNLNDVGN-- 555
++++ + E EL N+K + Q + F +
Sbjct: 476 ELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQET 535
Query: 556 MINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEE 615
M+ ++K+ Q+E L+ + + L + + +L K+E I+ LN+K +
Sbjct: 536 MLRDLQEKI-----NQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSK 590
Query: 616 HMNIINLLHNKLELRNE 632
L + LEL+ +
Sbjct: 591 TEKESKALLSALELKKK 607
>X95654-1|CAA64956.1| 976|Homo sapiens polypeptide of 976 aa
protein.
Length = 976
Score = 52.8 bits (121), Expect = 4e-06
Identities = 74/370 (20%), Positives = 146/370 (39%), Gaps = 22/370 (5%)
Query: 276 KDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKL 335
+D++++ E + K E + Q E ++ ++ ED +
Sbjct: 293 RDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTI 352
Query: 336 TQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEI 395
Q ++ T +E+ AR S + + E N + K++ +
Sbjct: 353 CQLTEEKETQMEESNKARAA--HSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTM 410
Query: 396 EKKYNDSIEEKKTLQENIDDLRTDLLESELRVKD-LVRELDEKESILETKQCVQKEL--- 451
E + S E+ T N ++ + L+ L K+ L+ E + E I E + ++EL
Sbjct: 411 ELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTEQELIGL 470
Query: 452 ----ESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXX 507
E DLE + T I ++ +E+ +LK++L EK +K+
Sbjct: 471 LQAREKEVHDLEIQLTAITTSEQYY---SKEVKDLKTELENEK-LKNTELTSHCNKLSLE 526
Query: 508 XXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFE- 566
E +K+ E++ N K Q + R +NL + + + + + E
Sbjct: 527 NKELTQETSDMTLE--LKNQQEDINNNKKQ--EERMLKQIENLQETETQLRNELEYVREE 582
Query: 567 LTKRQEEYDEKLQTKE---NEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLL 623
L ++++E KL E N +++ VE+ + L ++ K +K E + +N+ +
Sbjct: 583 LKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIK 642
Query: 624 HNKLELRNEA 633
NKLEL E+
Sbjct: 643 VNKLELELES 652
Score = 43.6 bits (98), Expect = 0.002
Identities = 60/272 (22%), Positives = 109/272 (40%), Gaps = 13/272 (4%)
Query: 374 YNKSIKDMKHEMNLNIAKLIEIEKKYNDS---IEEKKTLQENIDD---LRTDLLESELRV 427
Y K I D + +++L + ++ E E K D +EE + +++ L+++ L+ +
Sbjct: 257 YKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQSIEK 316
Query: 428 KD-LVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKL 486
+ L +EL++ + L+ QK LE ++ E K E+ + S +
Sbjct: 317 QHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNKARAAHSFV 376
Query: 487 STEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMK-SYYEELMNL-KNQITQLREF 544
TE E Q K S EE+ L N+ +L E
Sbjct: 377 VTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEEL 436
Query: 545 GAFDNLNDVGNMINQQRDKLF-ELTKRQEEYDEKLQTKENEIKRL---VESMTEQEHVLN 600
+ N+Q +K+ EL ++E LQ +E E+ L + ++T E +
Sbjct: 437 KKVLGEKETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYS 496
Query: 601 KKEKEIKMLNEKEEEHMNIINLLHNKLELRNE 632
K+ K++K E E+ + NKL L N+
Sbjct: 497 KEVKDLKTELENEKLKNTELTSHCNKLSLENK 528
Score = 43.2 bits (97), Expect = 0.003
Identities = 58/288 (20%), Positives = 122/288 (42%), Gaps = 17/288 (5%)
Query: 380 DMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKES 439
+M ++ + K+ +E++Y I +K ++ + L + E E ++KDL L+E
Sbjct: 238 EMHFKLKEDYEKIQHLEQEYKKEINDK---EKQVSLLLIQITEKENKMKDLTFLLEE--- 291
Query: 440 ILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKD---IX 496
++ V + E TK E+ K IE+ L E + L+ +ST+KA+++ I
Sbjct: 292 ---SRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIA 348
Query: 497 XXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNM 556
S + + +E + ++ + + N + + +
Sbjct: 349 TKTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKIL 408
Query: 557 INQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEH 616
+ + K EL EE + KE E++ L + + E+E +L + ++ K+ E +
Sbjct: 409 TMELQKKSSEL----EEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTE 464
Query: 617 MNIINLLHNKLELRNEADIDV-IITLAKYKKSLTLVLEKMSISNRVLK 663
+I LL + + ++ +I + IT ++ S + K + N LK
Sbjct: 465 QELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLK 512
Score = 39.5 bits (88), Expect = 0.040
Identities = 41/219 (18%), Positives = 92/219 (42%), Gaps = 8/219 (3%)
Query: 276 KDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKL 335
++ ++ + Q + ++++ L+ Q R+E + + + ++ N L
Sbjct: 545 QEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNL 604
Query: 336 TQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEI 395
+ +++ ++E++ + L+ NK ++ E+ K EI
Sbjct: 605 RKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNK----LELELESAKQKFGEI 660
Query: 396 EKKYNDSIEEKKTLQEN-IDDLRTDLLESELRVKDLVRELDEK--ESILETKQCVQKELE 452
Y IE+KK +EN ++++ + ++ VK L +E+D++ I E ++K
Sbjct: 661 TDTYQKEIEDKKISEENLLEEVEKAKVIADEAVK-LQKEIDKRCQHKIAEMVALMEKHKH 719
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
+E R +E+ YK E+ L+ +LS KA
Sbjct: 720 QYDKIIEERDSELGLYKSKEQEQSSLRASLEIELSNLKA 758
>BC126266-1|AAI26267.1| 976|Homo sapiens synaptonemal complex
protein 1 protein.
Length = 976
Score = 52.8 bits (121), Expect = 4e-06
Identities = 74/370 (20%), Positives = 146/370 (39%), Gaps = 22/370 (5%)
Query: 276 KDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKL 335
+D++++ E + K E + Q E ++ ++ ED +
Sbjct: 293 RDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTI 352
Query: 336 TQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEI 395
Q ++ T +E+ AR S + + E N + K++ +
Sbjct: 353 CQLTEEKETQMEESNKARAA--HSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTM 410
Query: 396 EKKYNDSIEEKKTLQENIDDLRTDLLESELRVKD-LVRELDEKESILETKQCVQKEL--- 451
E + S E+ T N ++ + L+ L K+ L+ E + E I E + ++EL
Sbjct: 411 ELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTEQELIGL 470
Query: 452 ----ESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXX 507
E DLE + T I ++ +E+ +LK++L EK +K+
Sbjct: 471 LQAREKEVHDLEIQLTAITTSEQYY---SKEVKDLKTELENEK-LKNTELTSHCNKLSLE 526
Query: 508 XXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFE- 566
E +K+ E++ N K Q + R +NL + + + + + E
Sbjct: 527 NKELTQETSDMTLE--LKNQQEDINNNKKQ--EERMLKQIENLQETETQLRNELEYVREE 582
Query: 567 LTKRQEEYDEKLQTKE---NEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLL 623
L ++++E KL E N +++ VE+ + L ++ K +K E + +N+ +
Sbjct: 583 LKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIK 642
Query: 624 HNKLELRNEA 633
NKLEL E+
Sbjct: 643 VNKLELELES 652
Score = 43.6 bits (98), Expect = 0.002
Identities = 60/272 (22%), Positives = 109/272 (40%), Gaps = 13/272 (4%)
Query: 374 YNKSIKDMKHEMNLNIAKLIEIEKKYNDS---IEEKKTLQENIDD---LRTDLLESELRV 427
Y K I D + +++L + ++ E E K D +EE + +++ L+++ L+ +
Sbjct: 257 YKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQSIEK 316
Query: 428 KD-LVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKL 486
+ L +EL++ + L+ QK LE ++ E K E+ + S +
Sbjct: 317 QHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNKARAAHSFV 376
Query: 487 STEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMK-SYYEELMNL-KNQITQLREF 544
TE E Q K S EE+ L N+ +L E
Sbjct: 377 VTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEEL 436
Query: 545 GAFDNLNDVGNMINQQRDKLF-ELTKRQEEYDEKLQTKENEIKRL---VESMTEQEHVLN 600
+ N+Q +K+ EL ++E LQ +E E+ L + ++T E +
Sbjct: 437 KKVLGEKETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYS 496
Query: 601 KKEKEIKMLNEKEEEHMNIINLLHNKLELRNE 632
K+ K++K E E+ + NKL L N+
Sbjct: 497 KEVKDLKTELENEKLKNTELTSHCNKLSLENK 528
Score = 43.2 bits (97), Expect = 0.003
Identities = 58/288 (20%), Positives = 122/288 (42%), Gaps = 17/288 (5%)
Query: 380 DMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKES 439
+M ++ + K+ +E++Y I +K ++ + L + E E ++KDL L+E
Sbjct: 238 EMHFKLKEDYEKIQHLEQEYKKEINDK---EKQVSLLLIQITEKENKMKDLTFLLEE--- 291
Query: 440 ILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKD---IX 496
++ V + E TK E+ K IE+ L E + L+ +ST+KA+++ I
Sbjct: 292 ---SRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIA 348
Query: 497 XXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNM 556
S + + +E + ++ + + N + + +
Sbjct: 349 TKTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKIL 408
Query: 557 INQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEH 616
+ + K EL EE + KE E++ L + + E+E +L + ++ K+ E +
Sbjct: 409 TMELQKKSSEL----EEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTE 464
Query: 617 MNIINLLHNKLELRNEADIDV-IITLAKYKKSLTLVLEKMSISNRVLK 663
+I LL + + ++ +I + IT ++ S + K + N LK
Sbjct: 465 QELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLK 512
Score = 39.5 bits (88), Expect = 0.040
Identities = 41/219 (18%), Positives = 92/219 (42%), Gaps = 8/219 (3%)
Query: 276 KDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKL 335
++ ++ + Q + ++++ L+ Q R+E + + + ++ N L
Sbjct: 545 QEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNL 604
Query: 336 TQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEI 395
+ +++ ++E++ + L+ NK ++ E+ K EI
Sbjct: 605 RKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNK----LELELESAKQKFGEI 660
Query: 396 EKKYNDSIEEKKTLQEN-IDDLRTDLLESELRVKDLVRELDEK--ESILETKQCVQKELE 452
Y IE+KK +EN ++++ + ++ VK L +E+D++ I E ++K
Sbjct: 661 TDTYQKEIEDKKISEENLLEEVEKAKVIADEAVK-LQKEIDKRCQHKIAEMVALMEKHKH 719
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
+E R +E+ YK E+ L+ +LS KA
Sbjct: 720 QYDKIIEERDSELGLYKSKEQEQSSLRASLEIELSNLKA 758
Score = 37.1 bits (82), Expect = 0.21
Identities = 53/234 (22%), Positives = 95/234 (40%), Gaps = 24/234 (10%)
Query: 410 QENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYK 469
QE + D +DL SE + + E E I + K + EL ++ L+ + IE +
Sbjct: 88 QEGLKD--SDLENSEGLSRVYSKLYKEAEKIKKWKVSTEAELRQKESKLQENRKIIEAQR 145
Query: 470 RLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYE 529
+ + E + K L E+ I++ E K YE
Sbjct: 146 KAIQEL--QFGNEKVSLKLEEGIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYE 203
Query: 530 E------LMNLKNQITQLREFGAFDNLN-DVGNMINQQRDKLFE----LTKRQEEYDEKL 578
M+L N I ++ AF+ L N + KL E + ++EY +++
Sbjct: 204 REETRQVYMDLNNNIEKM--ITAFEELRVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEI 261
Query: 579 QTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNE 632
KE ++ L+ +TE+E+ K K++ L E+ + +N L K +L++E
Sbjct: 262 NDKEKQVSLLLIQITEKEN----KMKDLTFLLEESRDK---VNQLEEKTKLQSE 308
>AY282407-1|AAP40331.1| 1116|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 1116
Score = 52.8 bits (121), Expect = 4e-06
Identities = 102/507 (20%), Positives = 197/507 (38%), Gaps = 49/507 (9%)
Query: 132 LLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLL----- 186
LL I N L ++ EE K+I+++ + L EK TL+ ++++ + D+
Sbjct: 187 LLTIENELKNEKEEKAELNKQIVHFQQELSLSEK--KNLTLSKEVQQIQSNYDIAIAELH 244
Query: 187 --KSSLDQLRTEFLKEINDIIDCLRKNANETMALQL-RTK--ELSCALSDLNTQNAEMR- 240
KS + + +K N+I R N ++L TK EL S N ++
Sbjct: 245 VQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELRTLDSVSQISNIDLLN 304
Query: 241 -KQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAA 299
+ + +G N +++ E+ +++E + +
Sbjct: 305 LRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQE--PNRENSFHSSIEAIWEECKE 362
Query: 300 LEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLED-----IALARE 354
+ +A S+ + + + E N+L + N L I +E
Sbjct: 363 IVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKE 422
Query: 355 KLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENID 414
+LQ +++ ++ + AK+ E+E +E +K + +
Sbjct: 423 ELQEKNVTLDVQIQHVVEG-KRALSELTQGVTCYKAKIKELET----ILETQKVERSHSA 477
Query: 415 DLRTDLLESELRVKDLVRELDE-----KESILETKQCVQKELESTKTDLEHRKTEIEEYK 469
L D+LE E + L R L E ++S+ TK KEL+ K ++ +++ K
Sbjct: 478 KLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELK-LKEEITQLTNNLQDMK 536
Query: 470 RLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYE 529
LL K EE E ++ TEK +++ +E E
Sbjct: 537 HLLQLKEEE--EETNRQETEKLKEEL--------SASSARTQNLKADLQRKEEDYADLKE 586
Query: 530 ELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLV 589
+L + K QI Q+++ + D ++ R K+ EL K++ + ++L K+ I++L
Sbjct: 587 KLTDAKKQIKQVQK--EVSVMRDEDKLL---RIKINELEKKKNQCSQELDMKQRTIQQLK 641
Query: 590 ESMTEQ--EHVLNKKEKEIKMLNEKEE 614
E + Q E + + E+ K LN KE+
Sbjct: 642 EQLNNQKVEEAIQQYERACKDLNVKEK 668
Score = 48.4 bits (110), Expect = 9e-05
Identities = 49/257 (19%), Positives = 108/257 (42%), Gaps = 8/257 (3%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD 435
+++K+ + + ++ ++ K EE L N+ D++ LL+ + ++ R+
Sbjct: 495 RNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMK-HLLQLKEEEEETNRQ-- 551
Query: 436 EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDI 495
E E + E ++ K DL+ ++ + + K L + ++I +++ ++S ++D
Sbjct: 552 ETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSV---MRDE 608
Query: 496 XXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGN 555
++ ++ E+L N K + + A +LN
Sbjct: 609 DKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEK 668
Query: 556 MINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEE 615
+I R L E + Q E D+ L+ K E++RL + + + N + E K +E
Sbjct: 669 IIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCN--DLETKNNQRSNKE 726
Query: 616 HMNIINLLHNKLELRNE 632
H N ++L L++E
Sbjct: 727 HENNTDVLGKLTNLQDE 743
Score = 38.7 bits (86), Expect = 0.070
Identities = 45/262 (17%), Positives = 107/262 (40%), Gaps = 6/262 (2%)
Query: 371 SASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDL 430
+A +K E+ +LI+ +++ E +L + ++ ++ R+K+L
Sbjct: 6 TACLELKFNQIKAELAKTKGELIKTKEELKKRENESDSLIQELETSIKKIITQNQRIKEL 65
Query: 431 VRELDEKESILETKQCVQKELEST--KTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLST 488
+ +D+KE + Q ++ +E+T D + I K + E E + KSK+ +
Sbjct: 66 INIIDQKEDTINEFQNLKSLMENTFKCNDKADTSSLIINNKLICNETVEVPKDSKSKICS 125
Query: 489 E-KAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRES-QMKSYYEELMNLKNQITQLREFGA 546
E K + + ++S +++ E+ +++ + Q G
Sbjct: 126 ERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNIAEIEDIR--VLQENNEGL 183
Query: 547 FDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEI 606
L + N + ++++ EL K+ + ++L E + L + + + + + E+
Sbjct: 184 RAFLLTIENELKNEKEEKAELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSNYDIAIAEL 243
Query: 607 KMLNEKEEEHMNIINLLHNKLE 628
+ K +E I L N++E
Sbjct: 244 HVQKSKNQEQEEKIMKLSNEIE 265
Score = 38.7 bits (86), Expect = 0.070
Identities = 69/366 (18%), Positives = 153/366 (41%), Gaps = 30/366 (8%)
Query: 1 MKQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQN 60
+K+EE E + +T E L E+ +++ S + LK Q K + K++L D +
Sbjct: 541 LKEEEEETNRQET-----EKLKEE--LSASSARTQNLKADLQRKEEDYADLKEKLTDAKK 593
Query: 61 QVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHST 120
Q+ ++ + + KLL K+N ++ + + QL + +E +
Sbjct: 594 QIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAI 653
Query: 121 LD-NKVTFDVN---KLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKI 176
+ D+N K++ +++ E+T ++ +++ E+ + + + ++T+ K
Sbjct: 654 QQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVL---EAKLEEVERLATELEKWKE 710
Query: 177 K--EFNAENDLLKSSLDQLRTEFLKEINDIIDCLRK-----NANETMALQLRTKELSCAL 229
K + +N+ + + T+ L ++ ++ D L++ NA+ L+ + ++ A
Sbjct: 711 KCNDLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAK 770
Query: 230 SDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIM---KDRLSRA-EHQ 285
N +N EM+K ++ D R + +N +D+L A E Q
Sbjct: 771 EAENIRNKEMKK--YAEDRERFFKQQNEMEILTAQLTEKDSDLQKWREERDQLVAALEIQ 828
Query: 286 LKTNVERVVQLEAALEQAR---SESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDN 342
LK + VQ + +EQ + SE+ +E + + + L+ S + +
Sbjct: 829 LKALISSNVQKDNEIEQLKRIISETSKIETQIMDIKPKRISSADPDKLQTEPLSTSFEIS 888
Query: 343 TTHLED 348
+ED
Sbjct: 889 RNKIED 894
>AL645502-1|CAH70064.1| 976|Homo sapiens synaptonemal complex
protein 1 protein.
Length = 976
Score = 52.8 bits (121), Expect = 4e-06
Identities = 74/370 (20%), Positives = 146/370 (39%), Gaps = 22/370 (5%)
Query: 276 KDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKL 335
+D++++ E + K E + Q E ++ ++ ED +
Sbjct: 293 RDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTI 352
Query: 336 TQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEI 395
Q ++ T +E+ AR S + + E N + K++ +
Sbjct: 353 CQLTEEKETQMEESNKARAA--HSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTM 410
Query: 396 EKKYNDSIEEKKTLQENIDDLRTDLLESELRVKD-LVRELDEKESILETKQCVQKEL--- 451
E + S E+ T N ++ + L+ L K+ L+ E + E I E + ++EL
Sbjct: 411 ELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTEQELIGL 470
Query: 452 ----ESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXX 507
E DLE + T I ++ +E+ +LK++L EK +K+
Sbjct: 471 LQAREKEVHDLEIQLTAITTSEQYY---SKEVKDLKTELENEK-LKNTELTSHCNKLSLE 526
Query: 508 XXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFE- 566
E +K+ E++ N K Q + R +NL + + + + + E
Sbjct: 527 NKELTQETSDMTLE--LKNQQEDINNNKKQ--EERMLKQIENLQETETQLRNELEYVREE 582
Query: 567 LTKRQEEYDEKLQTKE---NEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLL 623
L ++++E KL E N +++ VE+ + L ++ K +K E + +N+ +
Sbjct: 583 LKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIK 642
Query: 624 HNKLELRNEA 633
NKLEL E+
Sbjct: 643 VNKLELELES 652
Score = 43.6 bits (98), Expect = 0.002
Identities = 60/272 (22%), Positives = 109/272 (40%), Gaps = 13/272 (4%)
Query: 374 YNKSIKDMKHEMNLNIAKLIEIEKKYNDS---IEEKKTLQENIDD---LRTDLLESELRV 427
Y K I D + +++L + ++ E E K D +EE + +++ L+++ L+ +
Sbjct: 257 YKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQSIEK 316
Query: 428 KD-LVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKL 486
+ L +EL++ + L+ QK LE ++ E K E+ + S +
Sbjct: 317 QHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNKARAAHSFV 376
Query: 487 STEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMK-SYYEELMNL-KNQITQLREF 544
TE E Q K S EE+ L N+ +L E
Sbjct: 377 VTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEEL 436
Query: 545 GAFDNLNDVGNMINQQRDKLF-ELTKRQEEYDEKLQTKENEIKRL---VESMTEQEHVLN 600
+ N+Q +K+ EL ++E LQ +E E+ L + ++T E +
Sbjct: 437 KKVLGEKETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYS 496
Query: 601 KKEKEIKMLNEKEEEHMNIINLLHNKLELRNE 632
K+ K++K E E+ + NKL L N+
Sbjct: 497 KEVKDLKTELENEKLKNTELTSHCNKLSLENK 528
Score = 43.2 bits (97), Expect = 0.003
Identities = 58/288 (20%), Positives = 122/288 (42%), Gaps = 17/288 (5%)
Query: 380 DMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKES 439
+M ++ + K+ +E++Y I +K ++ + L + E E ++KDL L+E
Sbjct: 238 EMHFKLKEDYEKIQHLEQEYKKEINDK---EKQVSLLLIQITEKENKMKDLTFLLEE--- 291
Query: 440 ILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKD---IX 496
++ V + E TK E+ K IE+ L E + L+ +ST+KA+++ I
Sbjct: 292 ---SRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIA 348
Query: 497 XXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNM 556
S + + +E + ++ + + N + + +
Sbjct: 349 TKTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKIL 408
Query: 557 INQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEH 616
+ + K EL EE + KE E++ L + + E+E +L + ++ K+ E +
Sbjct: 409 TMELQKKSSEL----EEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTE 464
Query: 617 MNIINLLHNKLELRNEADIDV-IITLAKYKKSLTLVLEKMSISNRVLK 663
+I LL + + ++ +I + IT ++ S + K + N LK
Sbjct: 465 QELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLK 512
Score = 39.5 bits (88), Expect = 0.040
Identities = 41/219 (18%), Positives = 92/219 (42%), Gaps = 8/219 (3%)
Query: 276 KDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKL 335
++ ++ + Q + ++++ L+ Q R+E + + + ++ N L
Sbjct: 545 QEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNL 604
Query: 336 TQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEI 395
+ +++ ++E++ + L+ NK ++ E+ K EI
Sbjct: 605 RKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNK----LELELESAKQKFGEI 660
Query: 396 EKKYNDSIEEKKTLQEN-IDDLRTDLLESELRVKDLVRELDEK--ESILETKQCVQKELE 452
Y IE+KK +EN ++++ + ++ VK L +E+D++ I E ++K
Sbjct: 661 TDTYQKEIEDKKISEENLLEEVEKAKVIADEAVK-LQKEIDKRCQHKIAEMVALMEKHKH 719
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
+E R +E+ YK E+ L+ +LS KA
Sbjct: 720 QYDKIIEERDSELGLYKSKEQEQSSLRASLEIELSNLKA 758
Score = 37.1 bits (82), Expect = 0.21
Identities = 53/234 (22%), Positives = 95/234 (40%), Gaps = 24/234 (10%)
Query: 410 QENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYK 469
QE + D +DL SE + + E E I + K + EL ++ L+ + IE +
Sbjct: 88 QEGLKD--SDLENSEGLSRVYSKLYKEAEKIKKWKVSTEAELRQKESKLQENRKIIEAQR 145
Query: 470 RLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYE 529
+ + E + K L E+ I++ E K YE
Sbjct: 146 KAIQEL--QFGNEKVSLKLEEGIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYE 203
Query: 530 E------LMNLKNQITQLREFGAFDNLN-DVGNMINQQRDKLFE----LTKRQEEYDEKL 578
M+L N I ++ AF+ L N + KL E + ++EY +++
Sbjct: 204 REETRQVYMDLNNNIEKM--ITAFEELRVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEI 261
Query: 579 QTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNE 632
KE ++ L+ +TE+E+ K K++ L E+ + +N L K +L++E
Sbjct: 262 NDKEKQVSLLLIQITEKEN----KMKDLTFLLEESRDK---VNQLEEKTKLQSE 308
>AL358372-3|CAH72848.1| 792|Homo sapiens synaptonemal complex
protein 1 protein.
Length = 792
Score = 52.8 bits (121), Expect = 4e-06
Identities = 74/370 (20%), Positives = 146/370 (39%), Gaps = 22/370 (5%)
Query: 276 KDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKL 335
+D++++ E + K E + Q E ++ ++ ED +
Sbjct: 293 RDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTI 352
Query: 336 TQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEI 395
Q ++ T +E+ AR S + + E N + K++ +
Sbjct: 353 CQLTEEKETQMEESNKARAA--HSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTM 410
Query: 396 EKKYNDSIEEKKTLQENIDDLRTDLLESELRVKD-LVRELDEKESILETKQCVQKEL--- 451
E + S E+ T N ++ + L+ L K+ L+ E + E I E + ++EL
Sbjct: 411 ELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTEQELIGL 470
Query: 452 ----ESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXX 507
E DLE + T I ++ +E+ +LK++L EK +K+
Sbjct: 471 LQAREKEVHDLEIQLTAITTSEQYY---SKEVKDLKTELENEK-LKNTELTSHCNKLSLE 526
Query: 508 XXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFE- 566
E +K+ E++ N K Q + R +NL + + + + + E
Sbjct: 527 NKELTQETSDMTLE--LKNQQEDINNNKKQ--EERMLKQIENLQETETQLRNELEYVREE 582
Query: 567 LTKRQEEYDEKLQTKE---NEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLL 623
L ++++E KL E N +++ VE+ + L ++ K +K E + +N+ +
Sbjct: 583 LKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIK 642
Query: 624 HNKLELRNEA 633
NKLEL E+
Sbjct: 643 VNKLELELES 652
Score = 43.6 bits (98), Expect = 0.002
Identities = 60/272 (22%), Positives = 109/272 (40%), Gaps = 13/272 (4%)
Query: 374 YNKSIKDMKHEMNLNIAKLIEIEKKYNDS---IEEKKTLQENIDD---LRTDLLESELRV 427
Y K I D + +++L + ++ E E K D +EE + +++ L+++ L+ +
Sbjct: 257 YKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQSIEK 316
Query: 428 KD-LVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKL 486
+ L +EL++ + L+ QK LE ++ E K E+ + S +
Sbjct: 317 QHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNKARAAHSFV 376
Query: 487 STEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMK-SYYEELMNL-KNQITQLREF 544
TE E Q K S EE+ L N+ +L E
Sbjct: 377 VTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEEL 436
Query: 545 GAFDNLNDVGNMINQQRDKLF-ELTKRQEEYDEKLQTKENEIKRL---VESMTEQEHVLN 600
+ N+Q +K+ EL ++E LQ +E E+ L + ++T E +
Sbjct: 437 KKVLGEKETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYS 496
Query: 601 KKEKEIKMLNEKEEEHMNIINLLHNKLELRNE 632
K+ K++K E E+ + NKL L N+
Sbjct: 497 KEVKDLKTELENEKLKNTELTSHCNKLSLENK 528
Score = 43.2 bits (97), Expect = 0.003
Identities = 58/288 (20%), Positives = 122/288 (42%), Gaps = 17/288 (5%)
Query: 380 DMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKES 439
+M ++ + K+ +E++Y I +K ++ + L + E E ++KDL L+E
Sbjct: 238 EMHFKLKEDYEKIQHLEQEYKKEINDK---EKQVSLLLIQITEKENKMKDLTFLLEE--- 291
Query: 440 ILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKD---IX 496
++ V + E TK E+ K IE+ L E + L+ +ST+KA+++ I
Sbjct: 292 ---SRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIA 348
Query: 497 XXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNM 556
S + + +E + ++ + + N + + +
Sbjct: 349 TKTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKIL 408
Query: 557 INQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEH 616
+ + K EL EE + KE E++ L + + E+E +L + ++ K+ E +
Sbjct: 409 TMELQKKSSEL----EEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTE 464
Query: 617 MNIINLLHNKLELRNEADIDV-IITLAKYKKSLTLVLEKMSISNRVLK 663
+I LL + + ++ +I + IT ++ S + K + N LK
Sbjct: 465 QELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLK 512
Score = 39.5 bits (88), Expect = 0.040
Identities = 41/219 (18%), Positives = 92/219 (42%), Gaps = 8/219 (3%)
Query: 276 KDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKL 335
++ ++ + Q + ++++ L+ Q R+E + + + ++ N L
Sbjct: 545 QEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNL 604
Query: 336 TQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEI 395
+ +++ ++E++ + L+ NK ++ E+ K EI
Sbjct: 605 RKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNK----LELELESAKQKFGEI 660
Query: 396 EKKYNDSIEEKKTLQEN-IDDLRTDLLESELRVKDLVRELDEK--ESILETKQCVQKELE 452
Y IE+KK +EN ++++ + ++ VK L +E+D++ I E ++K
Sbjct: 661 TDTYQKEIEDKKISEENLLEEVEKAKVIADEAVK-LQKEIDKRCQHKIAEMVALMEKHKH 719
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
+E R +E+ YK E+ L+ +LS KA
Sbjct: 720 QYDKIIEERDSELGLYKSKEQEQSSLRASLEIELSNLKA 758
Score = 37.1 bits (82), Expect = 0.21
Identities = 53/234 (22%), Positives = 95/234 (40%), Gaps = 24/234 (10%)
Query: 410 QENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYK 469
QE + D +DL SE + + E E I + K + EL ++ L+ + IE +
Sbjct: 88 QEGLKD--SDLENSEGLSRVYSKLYKEAEKIKKWKVSTEAELRQKESKLQENRKIIEAQR 145
Query: 470 RLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYE 529
+ + E + K L E+ I++ E K YE
Sbjct: 146 KAIQEL--QFGNEKVSLKLEEGIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYE 203
Query: 530 E------LMNLKNQITQLREFGAFDNLN-DVGNMINQQRDKLFE----LTKRQEEYDEKL 578
M+L N I ++ AF+ L N + KL E + ++EY +++
Sbjct: 204 REETRQVYMDLNNNIEKM--ITAFEELRVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEI 261
Query: 579 QTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNE 632
KE ++ L+ +TE+E+ K K++ L E+ + +N L K +L++E
Sbjct: 262 NDKEKQVSLLLIQITEKEN----KMKDLTFLLEESRDK---VNQLEEKTKLQSE 308
>AL358372-2|CAH72847.1| 976|Homo sapiens synaptonemal complex
protein 1 protein.
Length = 976
Score = 52.8 bits (121), Expect = 4e-06
Identities = 74/370 (20%), Positives = 146/370 (39%), Gaps = 22/370 (5%)
Query: 276 KDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKL 335
+D++++ E + K E + Q E ++ ++ ED +
Sbjct: 293 RDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTI 352
Query: 336 TQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEI 395
Q ++ T +E+ AR S + + E N + K++ +
Sbjct: 353 CQLTEEKETQMEESNKARAA--HSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTM 410
Query: 396 EKKYNDSIEEKKTLQENIDDLRTDLLESELRVKD-LVRELDEKESILETKQCVQKEL--- 451
E + S E+ T N ++ + L+ L K+ L+ E + E I E + ++EL
Sbjct: 411 ELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTEQELIGL 470
Query: 452 ----ESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXX 507
E DLE + T I ++ +E+ +LK++L EK +K+
Sbjct: 471 LQAREKEVHDLEIQLTAITTSEQYY---SKEVKDLKTELENEK-LKNTELTSHCNKLSLE 526
Query: 508 XXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFE- 566
E +K+ E++ N K Q + R +NL + + + + + E
Sbjct: 527 NKELTQETSDMTLE--LKNQQEDINNNKKQ--EERMLKQIENLQETETQLRNELEYVREE 582
Query: 567 LTKRQEEYDEKLQTKE---NEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLL 623
L ++++E KL E N +++ VE+ + L ++ K +K E + +N+ +
Sbjct: 583 LKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIK 642
Query: 624 HNKLELRNEA 633
NKLEL E+
Sbjct: 643 VNKLELELES 652
Score = 43.6 bits (98), Expect = 0.002
Identities = 60/272 (22%), Positives = 109/272 (40%), Gaps = 13/272 (4%)
Query: 374 YNKSIKDMKHEMNLNIAKLIEIEKKYNDS---IEEKKTLQENIDD---LRTDLLESELRV 427
Y K I D + +++L + ++ E E K D +EE + +++ L+++ L+ +
Sbjct: 257 YKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQSIEK 316
Query: 428 KD-LVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKL 486
+ L +EL++ + L+ QK LE ++ E K E+ + S +
Sbjct: 317 QHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNKARAAHSFV 376
Query: 487 STEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMK-SYYEELMNL-KNQITQLREF 544
TE E Q K S EE+ L N+ +L E
Sbjct: 377 VTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEEL 436
Query: 545 GAFDNLNDVGNMINQQRDKLF-ELTKRQEEYDEKLQTKENEIKRL---VESMTEQEHVLN 600
+ N+Q +K+ EL ++E LQ +E E+ L + ++T E +
Sbjct: 437 KKVLGEKETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYS 496
Query: 601 KKEKEIKMLNEKEEEHMNIINLLHNKLELRNE 632
K+ K++K E E+ + NKL L N+
Sbjct: 497 KEVKDLKTELENEKLKNTELTSHCNKLSLENK 528
Score = 43.2 bits (97), Expect = 0.003
Identities = 58/288 (20%), Positives = 122/288 (42%), Gaps = 17/288 (5%)
Query: 380 DMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKES 439
+M ++ + K+ +E++Y I +K ++ + L + E E ++KDL L+E
Sbjct: 238 EMHFKLKEDYEKIQHLEQEYKKEINDK---EKQVSLLLIQITEKENKMKDLTFLLEE--- 291
Query: 440 ILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKD---IX 496
++ V + E TK E+ K IE+ L E + L+ +ST+KA+++ I
Sbjct: 292 ---SRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIA 348
Query: 497 XXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNM 556
S + + +E + ++ + + N + + +
Sbjct: 349 TKTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKIL 408
Query: 557 INQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEH 616
+ + K EL EE + KE E++ L + + E+E +L + ++ K+ E +
Sbjct: 409 TMELQKKSSEL----EEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTE 464
Query: 617 MNIINLLHNKLELRNEADIDV-IITLAKYKKSLTLVLEKMSISNRVLK 663
+I LL + + ++ +I + IT ++ S + K + N LK
Sbjct: 465 QELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLK 512
Score = 39.5 bits (88), Expect = 0.040
Identities = 41/219 (18%), Positives = 92/219 (42%), Gaps = 8/219 (3%)
Query: 276 KDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKL 335
++ ++ + Q + ++++ L+ Q R+E + + + ++ N L
Sbjct: 545 QEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNL 604
Query: 336 TQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEI 395
+ +++ ++E++ + L+ NK ++ E+ K EI
Sbjct: 605 RKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNK----LELELESAKQKFGEI 660
Query: 396 EKKYNDSIEEKKTLQEN-IDDLRTDLLESELRVKDLVRELDEK--ESILETKQCVQKELE 452
Y IE+KK +EN ++++ + ++ VK L +E+D++ I E ++K
Sbjct: 661 TDTYQKEIEDKKISEENLLEEVEKAKVIADEAVK-LQKEIDKRCQHKIAEMVALMEKHKH 719
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
+E R +E+ YK E+ L+ +LS KA
Sbjct: 720 QYDKIIEERDSELGLYKSKEQEQSSLRASLEIELSNLKA 758
Score = 37.1 bits (82), Expect = 0.21
Identities = 53/234 (22%), Positives = 95/234 (40%), Gaps = 24/234 (10%)
Query: 410 QENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYK 469
QE + D +DL SE + + E E I + K + EL ++ L+ + IE +
Sbjct: 88 QEGLKD--SDLENSEGLSRVYSKLYKEAEKIKKWKVSTEAELRQKESKLQENRKIIEAQR 145
Query: 470 RLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYE 529
+ + E + K L E+ I++ E K YE
Sbjct: 146 KAIQEL--QFGNEKVSLKLEEGIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYE 203
Query: 530 E------LMNLKNQITQLREFGAFDNLN-DVGNMINQQRDKLFE----LTKRQEEYDEKL 578
M+L N I ++ AF+ L N + KL E + ++EY +++
Sbjct: 204 REETRQVYMDLNNNIEKM--ITAFEELRVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEI 261
Query: 579 QTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNE 632
KE ++ L+ +TE+E+ K K++ L E+ + +N L K +L++E
Sbjct: 262 NDKEKQVSLLLIQITEKEN----KMKDLTFLLEESRDK---VNQLEEKTKLQSE 308
>AF273043-1|AAG34903.1| 795|Homo sapiens CTCL tumor antigen se2-1
protein.
Length = 795
Score = 52.8 bits (121), Expect = 4e-06
Identities = 74/370 (20%), Positives = 146/370 (39%), Gaps = 22/370 (5%)
Query: 276 KDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKL 335
+D++++ E + K E + Q E ++ ++ ED +
Sbjct: 293 RDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTI 352
Query: 336 TQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEI 395
Q ++ T +E+ AR S + + E N + K++ +
Sbjct: 353 CQLTEEKETQMEESNKARAA--HSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTM 410
Query: 396 EKKYNDSIEEKKTLQENIDDLRTDLLESELRVKD-LVRELDEKESILETKQCVQKEL--- 451
E + S E+ T N ++ + L+ L K+ L+ E + E I E + ++EL
Sbjct: 411 ELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTEQELIGL 470
Query: 452 ----ESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXX 507
E DLE + T I ++ +E+ +LK++L EK +K+
Sbjct: 471 LQAREKEVHDLEIQLTAITTSEQYY---SKEVKDLKTELENEK-LKNTELTSHCNKLSLE 526
Query: 508 XXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFE- 566
E +K+ E++ N K Q + R +NL + + + + + E
Sbjct: 527 NKELTQETSDMTLE--LKNQQEDINNNKKQ--EERMLKQIENLQETETQLRNELEYVREE 582
Query: 567 LTKRQEEYDEKLQTKE---NEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLL 623
L ++++E KL E N +++ VE+ + L ++ K +K E + +N+ +
Sbjct: 583 LKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIK 642
Query: 624 HNKLELRNEA 633
NKLEL E+
Sbjct: 643 VNKLELELES 652
Score = 43.6 bits (98), Expect = 0.002
Identities = 60/272 (22%), Positives = 109/272 (40%), Gaps = 13/272 (4%)
Query: 374 YNKSIKDMKHEMNLNIAKLIEIEKKYNDS---IEEKKTLQENIDD---LRTDLLESELRV 427
Y K I D + +++L + ++ E E K D +EE + +++ L+++ L+ +
Sbjct: 257 YKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQSIEK 316
Query: 428 KD-LVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKL 486
+ L +EL++ + L+ QK LE ++ E K E+ + S +
Sbjct: 317 QHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNKARAAHSFV 376
Query: 487 STEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMK-SYYEELMNL-KNQITQLREF 544
TE E Q K S EE+ L N+ +L E
Sbjct: 377 VTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEEL 436
Query: 545 GAFDNLNDVGNMINQQRDKLF-ELTKRQEEYDEKLQTKENEIKRL---VESMTEQEHVLN 600
+ N+Q +K+ EL ++E LQ +E E+ L + ++T E +
Sbjct: 437 KKVLGEKETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYS 496
Query: 601 KKEKEIKMLNEKEEEHMNIINLLHNKLELRNE 632
K+ K++K E E+ + NKL L N+
Sbjct: 497 KEVKDLKTELENEKLKNTELTSHCNKLSLENK 528
Score = 43.2 bits (97), Expect = 0.003
Identities = 58/288 (20%), Positives = 122/288 (42%), Gaps = 17/288 (5%)
Query: 380 DMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKES 439
+M ++ + K+ +E++Y I +K ++ + L + E E ++KDL L+E
Sbjct: 238 EMHFKLKEDYEKIQHLEQEYKKEINDK---EKQVSLLLIQITEKENKMKDLTFLLEE--- 291
Query: 440 ILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKD---IX 496
++ V + E TK E+ K IE+ L E + L+ +ST+KA+++ I
Sbjct: 292 ---SRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIA 348
Query: 497 XXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNM 556
S + + +E + ++ + + N + + +
Sbjct: 349 TKTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKIL 408
Query: 557 INQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEH 616
+ + K EL EE + KE E++ L + + E+E +L + ++ K+ E +
Sbjct: 409 TMELQKKSSEL----EEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTE 464
Query: 617 MNIINLLHNKLELRNEADIDV-IITLAKYKKSLTLVLEKMSISNRVLK 663
+I LL + + ++ +I + IT ++ S + K + N LK
Sbjct: 465 QELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLK 512
Score = 39.5 bits (88), Expect = 0.040
Identities = 41/219 (18%), Positives = 92/219 (42%), Gaps = 8/219 (3%)
Query: 276 KDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKL 335
++ ++ + Q + ++++ L+ Q R+E + + + ++ N L
Sbjct: 545 QEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNL 604
Query: 336 TQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEI 395
+ +++ ++E++ + L+ NK ++ E+ K EI
Sbjct: 605 RKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNK----LELELESAKQKFGEI 660
Query: 396 EKKYNDSIEEKKTLQEN-IDDLRTDLLESELRVKDLVRELDEK--ESILETKQCVQKELE 452
Y IE+KK +EN ++++ + ++ VK L +E+D++ I E ++K
Sbjct: 661 TDTYQKEIEDKKISEENLLEEVEKAKVIADEAVK-LQKEIDKRCQHKIAEMVALMEKHKH 719
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
+E R +E+ YK E+ L+ +LS KA
Sbjct: 720 QYDKIIEERDSELGLYKSKEQEQSSLRASLEIELSNLKA 758
Score = 37.1 bits (82), Expect = 0.21
Identities = 53/234 (22%), Positives = 95/234 (40%), Gaps = 24/234 (10%)
Query: 410 QENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYK 469
QE + D +DL SE + + E E I + K + EL ++ L+ + IE +
Sbjct: 88 QEGLKD--SDLENSEGLSRVYSKLYKEAEKIKKWKVSTEAELRQKESKLQENRKIIEAQR 145
Query: 470 RLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYE 529
+ + E + K L E+ I++ E K YE
Sbjct: 146 KAIQEL--QFGNEKVSLKLEEGIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYE 203
Query: 530 E------LMNLKNQITQLREFGAFDNLN-DVGNMINQQRDKLFE----LTKRQEEYDEKL 578
M+L N I ++ AF+ L N + KL E + ++EY +++
Sbjct: 204 REETRQVYMDLNNNIEKM--ITAFEELRVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEI 261
Query: 579 QTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNE 632
KE ++ L+ +TE+E+ K K++ L E+ + +N L K +L++E
Sbjct: 262 NDKEKQVSLLLIQITEKEN----KMKDLTFLLEESRDK---VNQLEEKTKLQSE 308
>AB033337-1|BAB69456.1| 1820|Homo sapiens mitotic kinesin-related
protein protein.
Length = 1820
Score = 52.8 bits (121), Expect = 4e-06
Identities = 102/507 (20%), Positives = 197/507 (38%), Gaps = 49/507 (9%)
Query: 132 LLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLL----- 186
LL I N L ++ EE K+I+++ + L EK TL+ ++++ + D+
Sbjct: 891 LLTIENELKNEKEEKAELNKQIVHFQQELSLSEK--KNLTLSKEVQQIQSNYDIAIAELH 948
Query: 187 --KSSLDQLRTEFLKEINDIIDCLRKNANETMALQL-RTK--ELSCALSDLNTQNAEMR- 240
KS + + +K N+I R N ++L TK EL S N ++
Sbjct: 949 VQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELRTLDSVSQISNIDLLN 1008
Query: 241 -KQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAA 299
+ + +G N +++ E+ +++E + +
Sbjct: 1009 LRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQE--PNRENSFHSSIEAIWEECKE 1066
Query: 300 LEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLED-----IALARE 354
+ +A S+ + + + E N+L + N L I +E
Sbjct: 1067 IVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKE 1126
Query: 355 KLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENID 414
+LQ +++ ++ + AK+ E+E +E +K + +
Sbjct: 1127 ELQEKNVTLDVQIQHVVEG-KRALSELTQGVTCYKAKIKELET----ILETQKVERSHSA 1181
Query: 415 DLRTDLLESELRVKDLVRELDE-----KESILETKQCVQKELESTKTDLEHRKTEIEEYK 469
L D+LE E + L R L E ++S+ TK KEL+ K ++ +++ K
Sbjct: 1182 KLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELK-LKEEITQLTNNLQDMK 1240
Query: 470 RLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYE 529
LL K EE E ++ TEK +++ +E E
Sbjct: 1241 HLLQLKEEE--EETNRQETEKLKEEL--------SASSARTQNLKADLQRKEEDYADLKE 1290
Query: 530 ELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLV 589
+L + K QI Q+++ + D ++ R K+ EL K++ + ++L K+ I++L
Sbjct: 1291 KLTDAKKQIKQVQK--EVSVMRDEDKLL---RIKINELEKKKNQCSQELDMKQRTIQQLK 1345
Query: 590 ESMTEQ--EHVLNKKEKEIKMLNEKEE 614
E + Q E + + E+ K LN KE+
Sbjct: 1346 EQLNNQKVEEAIQQYERACKDLNVKEK 1372
Score = 48.4 bits (110), Expect = 9e-05
Identities = 49/257 (19%), Positives = 108/257 (42%), Gaps = 8/257 (3%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD 435
+++K+ + + ++ ++ K EE L N+ D++ LL+ + ++ R+
Sbjct: 1199 RNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMK-HLLQLKEEEEETNRQ-- 1255
Query: 436 EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDI 495
E E + E ++ K DL+ ++ + + K L + ++I +++ ++S ++D
Sbjct: 1256 ETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSV---MRDE 1312
Query: 496 XXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGN 555
++ ++ E+L N K + + A +LN
Sbjct: 1313 DKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEK 1372
Query: 556 MINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEE 615
+I R L E + Q E D+ L+ K E++RL + + + N + E K +E
Sbjct: 1373 IIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCN--DLETKNNQRSNKE 1430
Query: 616 HMNIINLLHNKLELRNE 632
H N ++L L++E
Sbjct: 1431 HENNTDVLGKLTNLQDE 1447
Score = 38.7 bits (86), Expect = 0.070
Identities = 69/366 (18%), Positives = 153/366 (41%), Gaps = 30/366 (8%)
Query: 1 MKQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQN 60
+K+EE E + +T E L E+ +++ S + LK Q K + K++L D +
Sbjct: 1245 LKEEEEETNRQET-----EKLKEE--LSASSARTQNLKADLQRKEEDYADLKEKLTDAKK 1297
Query: 61 QVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHST 120
Q+ ++ + + KLL K+N ++ + + QL + +E +
Sbjct: 1298 QIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAI 1357
Query: 121 LD-NKVTFDVN---KLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKI 176
+ D+N K++ +++ E+T ++ +++ E+ + + + ++T+ K
Sbjct: 1358 QQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVL---EAKLEEVERLATELEKWKE 1414
Query: 177 K--EFNAENDLLKSSLDQLRTEFLKEINDIIDCLRK-----NANETMALQLRTKELSCAL 229
K + +N+ + + T+ L ++ ++ D L++ NA+ L+ + ++ A
Sbjct: 1415 KCNDLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAK 1474
Query: 230 SDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIM---KDRLSRA-EHQ 285
N +N EM+K ++ D R + +N +D+L A E Q
Sbjct: 1475 EAENIRNKEMKK--YAEDRERFFKQQNEMEILTAQLTEKDSDLQKWREERDQLVAALEIQ 1532
Query: 286 LKTNVERVVQLEAALEQAR---SESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDN 342
LK + VQ + +EQ + SE+ +E + + + L+ S + +
Sbjct: 1533 LKALISSNVQKDNEIEQLKRIISETSKIETQIMDIKPKRISSADPDKLQTEPLSTSFEIS 1592
Query: 343 TTHLED 348
+ED
Sbjct: 1593 RNKIED 1598
Score = 37.5 bits (83), Expect = 0.16
Identities = 45/262 (17%), Positives = 106/262 (40%), Gaps = 6/262 (2%)
Query: 371 SASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDL 430
+A +K E+ +LI+ +++ E +L + + ++ R+K+L
Sbjct: 710 TACLELKFNQIKAELAKTKGELIKTKEELKKRENESDSLIQELKTSIKKIITQNQRIKEL 769
Query: 431 VRELDEKESILETKQCVQKELEST--KTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLST 488
+ +D+KE + Q ++ +E+T D + I K + E E + KSK+ +
Sbjct: 770 INIIDQKEDTINEFQNLKSLMENTFKCNDKADTSSLIINNKLICNETVEVPKDSKSKICS 829
Query: 489 E-KAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRES-QMKSYYEELMNLKNQITQLREFGA 546
E K + + ++S +++ E+ +++ + Q G
Sbjct: 830 ERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNIAEIEDIR--VLQENNEGL 887
Query: 547 FDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEI 606
L + N + ++++ EL K+ + ++L E + L + + + + + E+
Sbjct: 888 RAFLLTIENELKNEKEEKAELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSNYDIAIAEL 947
Query: 607 KMLNEKEEEHMNIINLLHNKLE 628
+ K +E I L N++E
Sbjct: 948 HVQKSKNQEQEEKIMKLSNEIE 969
>U93121-1|AAB88727.1| 753|Homo sapiens M-phase phosphoprotein-1
protein.
Length = 753
Score = 52.4 bits (120), Expect = 5e-06
Identities = 55/225 (24%), Positives = 99/225 (44%), Gaps = 23/225 (10%)
Query: 397 KKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDE-----KESILETKQCVQKEL 451
K+ +E +K + + L D+LE E + L R L E ++S+ TK KEL
Sbjct: 97 KELETILETQKVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKEL 156
Query: 452 ESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXX 511
+ K ++ +++ K LL K EE E ++ TEK +++
Sbjct: 157 K-LKEEITQLTNNLQDMKHLLQLKEEE--EETNRQETEKLKEEL--------SASSARTQ 205
Query: 512 XXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQ 571
+E E+L + K QI Q+++ + D ++ R K+ EL K++
Sbjct: 206 NLKADLQRKEEDYADLKEKLTDAKKQIKQVQK--EVSVMRDEDKLL---RIKINELEKKK 260
Query: 572 EEYDEKLQTKENEIKRLVESMTEQ--EHVLNKKEKEIKMLNEKEE 614
+ ++L K+ I++L E + Q E + + E+ K LN KE+
Sbjct: 261 NQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEK 305
Score = 48.4 bits (110), Expect = 9e-05
Identities = 49/257 (19%), Positives = 108/257 (42%), Gaps = 8/257 (3%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD 435
+++K+ + + ++ ++ K EE L N+ D++ LL+ + ++ R+
Sbjct: 132 RNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMK-HLLQLKEEEEETNRQ-- 188
Query: 436 EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDI 495
E E + E ++ K DL+ ++ + + K L + ++I +++ ++S ++D
Sbjct: 189 ETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSV---MRDE 245
Query: 496 XXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGN 555
++ ++ E+L N K + + A +LN
Sbjct: 246 DKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEK 305
Query: 556 MINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEE 615
+I R L E + Q E D+ L+ K E++RL + + + N + E K +E
Sbjct: 306 IIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCN--DLETKNNQRSNKE 363
Query: 616 HMNIINLLHNKLELRNE 632
H N ++L L++E
Sbjct: 364 HENNTDVLGKLTNLQDE 380
Score = 38.7 bits (86), Expect = 0.070
Identities = 69/366 (18%), Positives = 153/366 (41%), Gaps = 30/366 (8%)
Query: 1 MKQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQN 60
+K+EE E + +T E L E+ +++ S + LK Q K + K++L D +
Sbjct: 178 LKEEEEETNRQET-----EKLKEE--LSASSARTQNLKADLQRKEEDYADLKEKLTDAKK 230
Query: 61 QVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHST 120
Q+ ++ + + KLL K+N ++ + + QL + +E +
Sbjct: 231 QIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAI 290
Query: 121 LD-NKVTFDVN---KLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKI 176
+ D+N K++ +++ E+T ++ +++ E+ + + + ++T+ K
Sbjct: 291 QQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVL---EAKLEEVERLATELEKWKE 347
Query: 177 K--EFNAENDLLKSSLDQLRTEFLKEINDIIDCLRK-----NANETMALQLRTKELSCAL 229
K + +N+ + + T+ L ++ ++ D L++ NA+ L+ + ++ A
Sbjct: 348 KCNDLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAK 407
Query: 230 SDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIM---KDRLSRA-EHQ 285
N +N EM+K ++ D R + +N +D+L A E Q
Sbjct: 408 EAENIRNKEMKK--YAEDRERFFKQQNEMEILTAQLTEKDSDLQKWREERDQLVAALEIQ 465
Query: 286 LKTNVERVVQLEAALEQAR---SESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDN 342
LK + VQ + +EQ + SE+ +E + + + L+ S + +
Sbjct: 466 LKALISSNVQKDNEIEQLKRIISETSKIETQIMDIKPKRISSADPDKLQTEPLSTSFEIS 525
Query: 343 TTHLED 348
+ED
Sbjct: 526 RNKIED 531
>AY739715-1|AAW65984.1| 617|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 617
Score = 52.4 bits (120), Expect = 5e-06
Identities = 55/225 (24%), Positives = 99/225 (44%), Gaps = 23/225 (10%)
Query: 397 KKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDE-----KESILETKQCVQKEL 451
K+ +E +K + + L D+LE E + L R L E ++S+ TK KEL
Sbjct: 59 KELETILETQKVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKEL 118
Query: 452 ESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXX 511
+ K ++ +++ K LL K EE E ++ TEK +++
Sbjct: 119 K-LKEEITQLTNNLQDMKHLLQLKEEE--EETNRQETEKLKEEL--------SASSARTQ 167
Query: 512 XXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQ 571
+E E+L + K QI Q+++ + D ++ R K+ EL K++
Sbjct: 168 NLKADLQRKEEDYADLKEKLTDAKKQIKQVQK--EVSVMRDEDKLL---RIKINELEKKK 222
Query: 572 EEYDEKLQTKENEIKRLVESMTEQ--EHVLNKKEKEIKMLNEKEE 614
+ ++L K+ I++L E + Q E + + E+ K LN KE+
Sbjct: 223 NQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEK 267
Score = 48.4 bits (110), Expect = 9e-05
Identities = 49/257 (19%), Positives = 108/257 (42%), Gaps = 8/257 (3%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD 435
+++K+ + + ++ ++ K EE L N+ D++ LL+ + ++ R+
Sbjct: 94 RNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMK-HLLQLKEEEEETNRQ-- 150
Query: 436 EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDI 495
E E + E ++ K DL+ ++ + + K L + ++I +++ ++S ++D
Sbjct: 151 ETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSV---MRDE 207
Query: 496 XXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGN 555
++ ++ E+L N K + + A +LN
Sbjct: 208 DKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEK 267
Query: 556 MINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEE 615
+I R L E + Q E D+ L+ K E++RL + + + N + E K +E
Sbjct: 268 IIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCN--DLETKNNQRSNKE 325
Query: 616 HMNIINLLHNKLELRNE 632
H N ++L L++E
Sbjct: 326 HENNTDVLGKLTNLQDE 342
Score = 38.7 bits (86), Expect = 0.070
Identities = 69/366 (18%), Positives = 153/366 (41%), Gaps = 30/366 (8%)
Query: 1 MKQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQN 60
+K+EE E + +T E L E+ +++ S + LK Q K + K++L D +
Sbjct: 140 LKEEEEETNRQET-----EKLKEE--LSASSARTQNLKADLQRKEEDYADLKEKLTDAKK 192
Query: 61 QVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHST 120
Q+ ++ + + KLL K+N ++ + + QL + +E +
Sbjct: 193 QIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAI 252
Query: 121 LD-NKVTFDVN---KLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKI 176
+ D+N K++ +++ E+T ++ +++ E+ + + + ++T+ K
Sbjct: 253 QQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVL---EAKLEEVERLATELEKWKE 309
Query: 177 K--EFNAENDLLKSSLDQLRTEFLKEINDIIDCLRK-----NANETMALQLRTKELSCAL 229
K + +N+ + + T+ L ++ ++ D L++ NA+ L+ + ++ A
Sbjct: 310 KCNDLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAK 369
Query: 230 SDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIM---KDRLSRA-EHQ 285
N +N EM+K ++ D R + +N +D+L A E Q
Sbjct: 370 EAENIRNKEMKK--YAEDRERFFKQQNEMEILTAQLTEKDSDLQKWREERDQLVAALEIQ 427
Query: 286 LKTNVERVVQLEAALEQAR---SESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDN 342
LK + VQ + +EQ + SE+ +E + + + L+ S + +
Sbjct: 428 LKALISSNVQKDNEIEQLKRIISETSKIETQIMDIKPKRISSADPDKLQTEPLSTSFEIS 487
Query: 343 TTHLED 348
+ED
Sbjct: 488 RNKIED 493
>AK126045-1|BAC86410.1| 978|Homo sapiens galactosaminyltransferase
9 protein.
Length = 978
Score = 52.4 bits (120), Expect = 5e-06
Identities = 105/623 (16%), Positives = 251/623 (40%), Gaps = 50/623 (8%)
Query: 24 QESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKV 83
+ +T + ++ L+ +EK+V + + + + ++ME +R+ + +K+
Sbjct: 250 ESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKI 309
Query: 84 NLP--SAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSL-- 139
L A+++H+ ++ +Q+ +L A E K + + ++ ++ + L
Sbjct: 310 CLAFEKAKKIHLEQHKEME-KQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLES 368
Query: 140 VDKC--EETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEF 197
+D+ E +KE + E+L + + +S +T+ K+++ ++ ++ K L +
Sbjct: 369 LDRLLTESKGEMKKENMKKDEALKALQNQVSEETI--KVRQLDSALEICKEELVLHLNQL 426
Query: 198 LKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNX 257
L+K + E LQ K + +L + + QN ++ H+ + +
Sbjct: 427 EGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQ---HTLQQQQQMLQQET 483
Query: 258 XXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXX 317
+ K + Q +++ E++ ++E E A E+ + V
Sbjct: 484 IRNGELEDTQTKLEKQVSKLE-QELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIEL 542
Query: 318 XXXXXXXXEDFDQ---ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASY 374
+ DQ EL+K+ + I E+ A+ +L + +
Sbjct: 543 TGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHFSQLDMILDQTKTELEKKTNAV 602
Query: 375 NKSIKDMKHEMNLNIAKLIE----IEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDL 430
K ++ ++H + + ++ +E + ++ E K+ + +LR L +++L
Sbjct: 603 -KELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQL----- 656
Query: 431 VRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS-TE 489
L+EK + ++ + EL K ++E K E+ E + L E+ E+ + ++++ +
Sbjct: 657 --SLEEKYTTIKD---LTAELRECKMEIEDEKQELLEMDQALKERNWELKQRAAQVTHLD 711
Query: 490 KAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDN 549
I++ Q++S ++L N K Q+ + +EF N
Sbjct: 712 MTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLRE-KEFIMLQN 770
Query: 550 LNDVGNMIN-----QQRDKLFE-LTKRQEEY-----------DEKLQTKENEIKRLVESM 592
++ + QQR K E + K QE+Y +KL+ +++ +
Sbjct: 771 EQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQCKEAIDLGQKLRLTREQVQNSHTEL 830
Query: 593 TEQEHVLNKKEKEIKMLNEKEEE 615
E H + ++EI+ L+ + E+
Sbjct: 831 AEARHQQVQAQREIERLSSELED 853
Score = 52.4 bits (120), Expect = 5e-06
Identities = 107/606 (17%), Positives = 240/606 (39%), Gaps = 49/606 (8%)
Query: 19 EDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKL 78
E++ + E++ + +++++ ++ E K+EL NQ L + +++K
Sbjct: 383 ENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQ---LEGNKEKFEKQLKK 439
Query: 79 LGQKVNLPSAEELHIMNVA-KLSPEQ--LLQLCAGGEPKALEHSTLDNKVTFDVNKLLNI 135
++V +EL I N + + + EQ +LQ + + L+ T+ N D L
Sbjct: 440 KSEEVYCLQ-KELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLE- 497
Query: 136 PNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKT-----LTMKIKEFNAENDLLKSSL 190
V K E+ L K++E + E L E+ + K+ E +K +
Sbjct: 498 --KQVSKLEQELQKQRE--SSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEM 553
Query: 191 DQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHR 250
DQ + E K +I+ R N+ M L ++L + + K++ H
Sbjct: 554 DQYKEELSKMEKEIMHLKRDGENKAMHFSQLDMILDQTKTELEKKTNAV-KELEKLQH-- 610
Query: 251 PYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQAR---SES 307
+++ L A +LK+ + ++ +L L++A+ E
Sbjct: 611 ---------STETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEK 661
Query: 308 WSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKL----QSXXXXX 363
++ + + ED QEL ++ Q++K+ L+ A L +
Sbjct: 662 YTTIKDLTAELRECKMEIEDEKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEM 721
Query: 364 XXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTL----QENIDDLRTD 419
+ KS ++K E N I L + + + + EK+ + ++ I L+ +
Sbjct: 722 EQKIIKLEGTLEKSELELK-ECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKE 780
Query: 420 LLESELRVKDLVRELDEKESILETKQCVQ-----KELESTKTDLEHRKTEIEEYKRLLFE 474
+ ++ R+K++ + E+E + T QC + ++L T+ +++ TE+ E + +
Sbjct: 781 IERTQQRMKEMESVMKEQEQYIAT-QCKEAIDLGQKLRLTREQVQNSHTELAEARHQQVQ 839
Query: 475 KGEEIDELKSKLSTEKAI-KDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMN 533
EI+ L S+L K + K+ ++++K E+ +
Sbjct: 840 AQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAEVES 899
Query: 534 LKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMT 593
LK + + +N + Q+ + +L ++ E+ +L+ ++ + L + +
Sbjct: 900 LK-EAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQ 958
Query: 594 EQEHVL 599
++ V+
Sbjct: 959 DRNEVI 964
Score = 45.6 bits (103), Expect = 6e-04
Identities = 84/509 (16%), Positives = 197/509 (38%), Gaps = 38/509 (7%)
Query: 172 LTMKIKEFNAENDLLK-------SSLDQLRTEFLKEIND---IIDCLRKNANETMALQLR 221
L K+ + AEN LK S ++ E L++ ++ + + K ++ + L+ +
Sbjct: 207 LRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQ 266
Query: 222 TKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSR 281
+E A S + +NAE+ +++ + N I ++
Sbjct: 267 LEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKE 326
Query: 282 AEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKD 341
E Q++ +LEA LE+ + E+T+ L L + + +
Sbjct: 327 MEKQIE-------RLEAQLEKKDQQFKEQEKTMSMLQQDIICK----QHHLESLDRLLTE 375
Query: 342 NTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLI----EIEK 397
+ ++ + +++ + +++ K E+ L++ +L + EK
Sbjct: 376 SKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEK 435
Query: 398 KYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTD 457
+ EE LQ+ + L E+ + L L +++ +L+ + ELE T+T
Sbjct: 436 QLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTK 495
Query: 458 LEHRKTEIE-EYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXX 516
LE + +++E E ++ E++ +++ K + D+
Sbjct: 496 LEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQV------ 549
Query: 517 XXXRESQMKSYYEELMNLKNQITQLREFGAFD--NLNDVGNMINQQRDKLFELTKRQEEY 574
+ +M Y EEL ++ +I L+ G + + + +++Q + +L + T +E
Sbjct: 550 ----KIEMDQYKEELSKMEKEIMHLKRDGENKAMHFSQLDMILDQTKTELEKKTNAVKEL 605
Query: 575 DEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEAD 634
++ + E E+ ++ E L E+K + +E +++ LE +
Sbjct: 606 EKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTI 665
Query: 635 IDVIITLAKYKKSLTLVLEKMSISNRVLK 663
D+ L + K + +++ ++ LK
Sbjct: 666 KDLTAELRECKMEIEDEKQELLEMDQALK 694
>AK024959-1|BAB15043.1| 696|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21306 fis, clone COL02125. ).
Length = 696
Score = 52.4 bits (120), Expect = 5e-06
Identities = 55/225 (24%), Positives = 99/225 (44%), Gaps = 23/225 (10%)
Query: 397 KKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDE-----KESILETKQCVQKEL 451
K+ +E +K + + L D+LE E + L R L E ++S+ TK KEL
Sbjct: 375 KELETILETQKVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKEL 434
Query: 452 ESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXX 511
+ K ++ +++ K LL K EE E ++ TEK +++
Sbjct: 435 K-LKEEITQLTNNLQDMKHLLQLKEEE--EETNRQETEKLKEEL--------SASSARTQ 483
Query: 512 XXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQ 571
+E E+L + K QI Q+++ + D ++ R K+ EL K++
Sbjct: 484 NLKADLQRKEEDYADLKEKLTDAKKQIKQVQK--EVSVMRDEDKLL---RIKINELEKKK 538
Query: 572 EEYDEKLQTKENEIKRLVESMTEQ--EHVLNKKEKEIKMLNEKEE 614
+ ++L K+ I++L E + Q E + + E+ K LN KE+
Sbjct: 539 NQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEK 583
Score = 48.4 bits (110), Expect = 9e-05
Identities = 49/257 (19%), Positives = 108/257 (42%), Gaps = 8/257 (3%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD 435
+++K+ + + ++ ++ K EE L N+ D++ LL+ + ++ R+
Sbjct: 410 RNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMK-HLLQLKEEEEETNRQ-- 466
Query: 436 EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDI 495
E E + E ++ K DL+ ++ + + K L + ++I +++ ++S ++D
Sbjct: 467 ETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSV---MRDE 523
Query: 496 XXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGN 555
++ ++ E+L N K + + A +LN
Sbjct: 524 DKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEK 583
Query: 556 MINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEE 615
+I R L E + Q E D+ L+ K E++RL + + + N + E K +E
Sbjct: 584 IIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCN--DLETKNNQRSNKE 641
Query: 616 HMNIINLLHNKLELRNE 632
H N ++L L++E
Sbjct: 642 HENNTDVLGKLTNLQDE 658
>D67035-1|BAA22586.1| 973|Homo sapiens SCP-1 protein.
Length = 973
Score = 52.0 bits (119), Expect = 7e-06
Identities = 71/373 (19%), Positives = 153/373 (41%), Gaps = 31/373 (8%)
Query: 276 KDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKL 335
+D++++ E + K E + Q E ++ ++ ED N +
Sbjct: 293 RDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATNTI 352
Query: 336 TQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEI 395
Q ++ T +E+ AR + +++ + I +E+
Sbjct: 353 CQLTEEKDTQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLENYEDQLIILTMEL 412
Query: 396 EKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESIL-ETKQC--VQKELE 452
+K ++ +EE L N E+ +++L + L EKE++L + KQ + +EL+
Sbjct: 413 QKTSSE-LEEMTKLTNN----------KEVELEELKKVLGEKETLLYDNKQFEKIAEELK 461
Query: 453 STKTDL----EHRKTEIE--EYKRLLFEKGEEIDEL--KSKLSTEKAIKDIXXXXXXXXX 504
T+ +L + R+ E+ EY + K + + + KLS+++ +K+
Sbjct: 462 GTEQELIGLLQAREKEVHDLEYSYCHYHKWTVLPKRGQRPKLSSKRELKNTEYFTLQQAS 521
Query: 505 XXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKL 564
++K+ E+++N K Q + R +NL + + + + +
Sbjct: 522 PPPNELTQETSDMTL---ELKNQQEDIINNKKQ--EERMLTQIENLQETETQLRNELEYV 576
Query: 565 FE-LTKRQEEYDEKLQTKE---NEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNII 620
E L ++++E KL E N +++ VE+ + L ++ K +K E + +N+
Sbjct: 577 REELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVY 636
Query: 621 NLLHNKLELRNEA 633
+ NKLEL E+
Sbjct: 637 EIKVNKLELELES 649
Score = 40.7 bits (91), Expect = 0.017
Identities = 43/214 (20%), Positives = 89/214 (41%), Gaps = 11/214 (5%)
Query: 281 RAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIK 340
+ E ++ T +E + + E Q R+E + + + ++ N L + ++
Sbjct: 550 KQEERMLTQIENLQETET---QLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVE 606
Query: 341 DNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYN 400
+ ++E++ + L+ NK ++ E+ K EI Y
Sbjct: 607 NKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNK----LELELESAKQKFGEITDTYQ 662
Query: 401 DSIEEKKTLQEN-IDDLRTDLLESELRVKDLVRELDEK--ESILETKQCVQKELESTKTD 457
IE+KK +EN ++++ + ++ VK L +E+D++ I E ++K
Sbjct: 663 KEIEDKKISEENLLEEVEKAKVIADEAVK-LQKEIDKRCQHKIAEMVALMEKHKHQYDKI 721
Query: 458 LEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
+E R +E+ YK E+ L+ +LS KA
Sbjct: 722 IEERDSELGLYKSKEQEQSSLRASLEIELSNLKA 755
Score = 39.5 bits (88), Expect = 0.040
Identities = 50/247 (20%), Positives = 102/247 (41%), Gaps = 16/247 (6%)
Query: 380 DMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKES 439
+M ++ + K+ +E++Y I +K ++ + L + E E ++KDL L+E
Sbjct: 238 EMHFKLKEDYEKIQHLEQEYKKEINDK---EKQVSLLLIQITEKENKMKDLTFLLEE--- 291
Query: 440 ILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKD---IX 496
++ V + E TK E+ K IE+ L E + L+ +ST+KA+++ I
Sbjct: 292 ---SRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIA 348
Query: 497 XXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNM 556
S + + +E + ++ + E +N D +
Sbjct: 349 TNTICQLTEEKDTQMEESNKARAAHSFVVTEFETTVCSLEELLR-TEQQRLENYEDQLII 407
Query: 557 INQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEH 616
+ + K + EE + KE E++ L + + E+E +L ++ K+ E +
Sbjct: 408 LTMELQK---TSSELEEMTKLTNNKEVELEELKKVLGEKETLLYDNKQFEKIAEELKGTE 464
Query: 617 MNIINLL 623
+I LL
Sbjct: 465 QELIGLL 471
Score = 36.7 bits (81), Expect = 0.28
Identities = 53/234 (22%), Positives = 96/234 (41%), Gaps = 24/234 (10%)
Query: 410 QENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYK 469
QE + D +DL SE + + E E I + K + EL ++ L+ + IE +
Sbjct: 88 QEGLKD--SDLENSEGLSRVYSKLYKEAEKIKKWKVSTEAELRQKESKLQENRKIIEAQR 145
Query: 470 RLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYE 529
+ + E + K L+ E+ I+D E K YE
Sbjct: 146 KAIQEL--QCGNEKVSLTLEEGIQDNKDLIKENNATRHLCNLLKETCARSAEKTKKYEYE 203
Query: 530 E------LMNLKNQITQLREFGAFDNLN-DVGNMINQQRDKLFE----LTKRQEEYDEKL 578
M+L + I ++ AF+ L N + KL E + ++EY +++
Sbjct: 204 REETRQVYMDLNSNIEKM--ITAFEELRVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEI 261
Query: 579 QTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNE 632
KE ++ L+ +TE+E+ K K++ L E+ + +N L K +L++E
Sbjct: 262 NDKEKQVSLLLIQITEKEN----KMKDLTFLLEESRDK---VNQLEEKTKLQSE 308
Score = 33.1 bits (72), Expect = 3.5
Identities = 54/261 (20%), Positives = 102/261 (39%), Gaps = 12/261 (4%)
Query: 374 YNKSIKDMKHEMNLNIAKLIEIEKKYNDS---IEEKKTLQENIDD---LRTDLLESELRV 427
Y K I D + +++L + ++ E E K D +EE + +++ L+++ L+ +
Sbjct: 257 YKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQSIEK 316
Query: 428 KD-LVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKL 486
+ L +EL++ + L+ QK LE + ++ E K E+ + S +
Sbjct: 317 QHHLTKELEDIKVSLQRSVSTQKALEEDLQIATNTICQLTEEKDTQMEESNKARAAHSFV 376
Query: 487 STEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQ-MKSYYEELMNL-KNQITQLREF 544
TE E Q S EE+ L N+ +L E
Sbjct: 377 VTEFETTVCSLEELLRTEQQRLENYEDQLIILTMELQKTSSELEEMTKLTNNKEVELEEL 436
Query: 545 GAFDNLNDVGNMINQQRDKLF-ELTKRQEEYDEKLQTKENEIKRLVESMTEQEH--VLNK 601
+ N+Q +K+ EL ++E LQ +E E+ L S VL K
Sbjct: 437 KKVLGEKETLLYDNKQFEKIAEELKGTEQELIGLLQAREKEVHDLEYSYCHYHKWTVLPK 496
Query: 602 KEKEIKMLNEKEEEHMNIINL 622
+ + K+ +++E ++ L
Sbjct: 497 RGQRPKLSSKRELKNTEYFTL 517
>AL132765-6|CAC10587.1| 977|Homo sapiens ribosome binding protein 1
homolog 180kDa (dog) protein.
Length = 977
Score = 52.0 bits (119), Expect = 7e-06
Identities = 45/221 (20%), Positives = 98/221 (44%), Gaps = 13/221 (5%)
Query: 278 RLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQ 337
RL E Q+ + ++L A+EQ + ++ L + ++L LTQ
Sbjct: 555 RLKELESQVSGLEKEAIELREAVEQQKVKNNDLREKNWKAMEALATAEQACKEKLLSLTQ 614
Query: 338 SIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAK------ 391
+ +++ L + + +++ +Y + ++D+K E + K
Sbjct: 615 AKEESEKQL--CLIEAQTMEALLALLPELSVLAQQNYTEWLQDLK-EKGPTLLKHPPAPA 671
Query: 392 --LIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETK-QCVQ 448
++ K ++ E + TLQ D R+ L E+E ++DL + ++E+E + K +
Sbjct: 672 EPSSDLASKLREAEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEEQVWRAKVGAAE 731
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
+EL+ ++ ++H + +E+ K L E +++ E S L E
Sbjct: 732 EELQKSRVTVKHLEEIVEKLKGEL-ESSDQVREHTSHLEAE 771
>AL132765-4|CAH74034.1| 1410|Homo sapiens ribosome binding protein 1
homolog 180kDa (dog) protein.
Length = 1410
Score = 52.0 bits (119), Expect = 7e-06
Identities = 45/221 (20%), Positives = 98/221 (44%), Gaps = 13/221 (5%)
Query: 278 RLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQ 337
RL E Q+ + ++L A+EQ + ++ L + ++L LTQ
Sbjct: 988 RLKELESQVSGLEKEAIELREAVEQQKVKNNDLREKNWKAMEALATAEQACKEKLLSLTQ 1047
Query: 338 SIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAK------ 391
+ +++ L + + +++ +Y + ++D+K E + K
Sbjct: 1048 AKEESEKQL--CLIEAQTMEALLALLPELSVLAQQNYTEWLQDLK-EKGPTLLKHPPAPA 1104
Query: 392 --LIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETK-QCVQ 448
++ K ++ E + TLQ D R+ L E+E ++DL + ++E+E + K +
Sbjct: 1105 EPSSDLASKLREAEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEEQVWRAKVGAAE 1164
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
+EL+ ++ ++H + +E+ K L E +++ E S L E
Sbjct: 1165 EELQKSRVTVKHLEEIVEKLKGEL-ESSDQVREHTSHLEAE 1204
>BC027860-1|AAH27860.1| 893|Homo sapiens filamin A interacting
protein 1-like protein.
Length = 893
Score = 51.6 bits (118), Expect = 9e-06
Identities = 62/331 (18%), Positives = 131/331 (39%), Gaps = 10/331 (3%)
Query: 170 KTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCAL 229
+ L K+ + + D L+ + LR + +E+ DI + + K + +EL +
Sbjct: 81 RQLQQKLAALSRQIDELEETNRSLR-KAEEELQDIKEKISKGEYGNAGIMAEVEELRKRV 139
Query: 230 SDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTN 289
D+ ++ E+ K R IM L + E +
Sbjct: 140 LDMEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLSKRIMA--LEKLEDAFNKS 197
Query: 290 VERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDI 349
+ L+ LE+ R + L + + E + L K ++K++ T L+ +
Sbjct: 198 KQECYSLKCNLEKERMTTKQLSQELESLKVRIKEL-EAIESRLEKTEFTLKEDLTKLKTL 256
Query: 350 ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEK---KYNDSIEEK 406
+ + + + ++ ++++ KLIE K K +EEK
Sbjct: 257 TVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEK 316
Query: 407 K-TLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRK--T 463
++ + DDL+ L E + DL+ ++ ++ L++ + ++K+ K + + K T
Sbjct: 317 MYSVTKERDDLKNKLKAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTT 376
Query: 464 EIEEYKRLLFEKGEEIDELKSKLSTEKAIKD 494
+ + + E +E++ LK KL KAI+D
Sbjct: 377 ALHQENNKIKELSQEVERLKLKLKDMKAIED 407
Score = 38.7 bits (86), Expect = 0.070
Identities = 65/368 (17%), Positives = 148/368 (40%), Gaps = 24/368 (6%)
Query: 278 RLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQ 337
+L+ AE +++ ++ +LE L+ ++ + T+ Q+L L++
Sbjct: 33 KLALAEARVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDSQNRQLQQKLAALSR 92
Query: 338 SIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH---EMNLNIAKLIE 394
I + + A E+LQ +A +++++ +M +LI+
Sbjct: 93 QIDELEETNRSLRKAEEELQDIKEKISKGEYG-NAGIMAEVEELRKRVLDMEGKDEELIK 151
Query: 395 IEKKYNDSIE--EKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELE 452
+E++ D + E++TLQ D + ++ + R+ L + D + ++ LE
Sbjct: 152 MEEQCRDLNKRLERETLQSK--DFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLE 209
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS-TEKAIKDIXXXXXXXXXXXXXXXX 511
+ + E+E K + +E++ ++S+L TE +K+
Sbjct: 210 KERMTTKQLSQELESLKVRI----KELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERK 265
Query: 512 XXXXXXXXRESQMKSYYEELMNLKNQITQLREF------GAFDNLNDVGNM---INQQRD 562
E ++++ +L +N++T + E A + DV + ++RD
Sbjct: 266 TMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERD 325
Query: 563 KLFELTKRQEEYDEKLQTKENEIKRLVESM--TEQEHVLNKKEKEIKMLNEKEEEHMNII 620
L K +EE L ++ N +K ++S+ E++ + NK ++ + N I
Sbjct: 326 DLKNKLKAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTTALHQENNKI 385
Query: 621 NLLHNKLE 628
L ++E
Sbjct: 386 KELSQEVE 393
Score = 37.5 bits (83), Expect = 0.16
Identities = 70/349 (20%), Positives = 139/349 (39%), Gaps = 29/349 (8%)
Query: 149 KRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKS---SLDQLRTEFLKEINDII 205
K +E+I E K + +TL + K+F E + L +L++L F K +
Sbjct: 145 KDEELIKMEEQCRDLNKRLERETL--QSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECY 202
Query: 206 DCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXX 265
L+ N + ++ TK+LS L L + E+ + I S + +
Sbjct: 203 S-LKCNLEKE---RMTTKQLSQELESLKVRIKEL-EAIESRLEKTEFTLKEDLTKLKTLT 257
Query: 266 XXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXX 325
M ++L + E +L+ + L+ +++ ++ +
Sbjct: 258 VMFVDERKTMSEKLKKTEDKLQA-------ASSQLQVEQNKVTTVTEKLIEETKRALKSK 310
Query: 326 EDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKD-MKHE 384
D ++++ +T+ D L+ A E+ + S KD +K++
Sbjct: 311 TDVEEKMYSVTKERDDLKNKLK----AEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNK 366
Query: 385 MNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETK 444
+N + K + N+ I+E L + ++ L+ L + + DL++ DE E++
Sbjct: 367 LNQDSGKSTTALHQENNKIKE---LSQEVERLKLKLKDMKAIEDDLMKTEDEYETLERRY 423
Query: 445 QCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE--LKSKLSTEKA 491
+ + + +LEH K E+ +YK L EK E E L +L E+A
Sbjct: 424 ANERDKAQFLSKELEHVKMELAKYK--LAEKTETSHEQWLFKRLQEEEA 470
>AY642382-1|AAV34207.1| 1135|Homo sapiens GPBP-interacting protein
130d protein.
Length = 1135
Score = 51.6 bits (118), Expect = 9e-06
Identities = 62/331 (18%), Positives = 131/331 (39%), Gaps = 10/331 (3%)
Query: 170 KTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCAL 229
+ L K+ + + D L+ + LR + +E+ DI + + K + +EL +
Sbjct: 321 RQLQQKLAALSRQIDELEETNRSLR-KAEEELQDIKEKISKGEYGNAGIMAEVEELRKRV 379
Query: 230 SDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTN 289
D+ ++ E+ K R IM L + E +
Sbjct: 380 LDMEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLSKRIMA--LEKLEDAFNKS 437
Query: 290 VERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDI 349
+ L+ LE+ R + L + + E + L K ++K++ T L+ +
Sbjct: 438 KQECYSLKCNLEKERMTTKQLSQELESLKVRIKEL-EAIESRLEKTEFTLKEDLTKLKTL 496
Query: 350 ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEK---KYNDSIEEK 406
+ + + + ++ ++++ KLIE K K +EEK
Sbjct: 497 TVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEK 556
Query: 407 K-TLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRK--T 463
++ + DDL+ L E + DL+ ++ ++ L++ + ++K+ K + + K T
Sbjct: 557 MYSVTKERDDLKNKLKAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTT 616
Query: 464 EIEEYKRLLFEKGEEIDELKSKLSTEKAIKD 494
+ + + E +E++ LK KL KAI+D
Sbjct: 617 ALHQENNKIKELSQEVERLKLKLKDMKAIED 647
Score = 38.7 bits (86), Expect = 0.070
Identities = 65/368 (17%), Positives = 148/368 (40%), Gaps = 24/368 (6%)
Query: 278 RLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQ 337
+L+ AE +++ ++ +LE L+ ++ + T+ Q+L L++
Sbjct: 273 KLALAEARVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDSQNRQLQQKLAALSR 332
Query: 338 SIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH---EMNLNIAKLIE 394
I + + A E+LQ +A +++++ +M +LI+
Sbjct: 333 QIDELEETNRSLRKAEEELQDIKEKISKGEYG-NAGIMAEVEELRKRVLDMEGKDEELIK 391
Query: 395 IEKKYNDSIE--EKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELE 452
+E++ D + E++TLQ D + ++ + R+ L + D + ++ LE
Sbjct: 392 MEEQCRDLNKRLERETLQSK--DFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLE 449
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS-TEKAIKDIXXXXXXXXXXXXXXXX 511
+ + E+E K + +E++ ++S+L TE +K+
Sbjct: 450 KERMTTKQLSQELESLKVRI----KELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERK 505
Query: 512 XXXXXXXXRESQMKSYYEELMNLKNQITQLREF------GAFDNLNDVGNM---INQQRD 562
E ++++ +L +N++T + E A + DV + ++RD
Sbjct: 506 TMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERD 565
Query: 563 KLFELTKRQEEYDEKLQTKENEIKRLVESM--TEQEHVLNKKEKEIKMLNEKEEEHMNII 620
L K +EE L ++ N +K ++S+ E++ + NK ++ + N I
Sbjct: 566 DLKNKLKAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTTALHQENNKI 625
Query: 621 NLLHNKLE 628
L ++E
Sbjct: 626 KELSQEVE 633
Score = 37.5 bits (83), Expect = 0.16
Identities = 70/349 (20%), Positives = 139/349 (39%), Gaps = 29/349 (8%)
Query: 149 KRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKS---SLDQLRTEFLKEINDII 205
K +E+I E K + +TL + K+F E + L +L++L F K +
Sbjct: 385 KDEELIKMEEQCRDLNKRLERETL--QSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECY 442
Query: 206 DCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXX 265
L+ N + ++ TK+LS L L + E+ + I S + +
Sbjct: 443 S-LKCNLEKE---RMTTKQLSQELESLKVRIKEL-EAIESRLEKTEFTLKEDLTKLKTLT 497
Query: 266 XXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXX 325
M ++L + E +L+ + L+ +++ ++ +
Sbjct: 498 VMFVDERKTMSEKLKKTEDKLQA-------ASSQLQVEQNKVTTVTEKLIEETKRALKSK 550
Query: 326 EDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKD-MKHE 384
D ++++ +T+ D L+ A E+ + S KD +K++
Sbjct: 551 TDVEEKMYSVTKERDDLKNKLK----AEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNK 606
Query: 385 MNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETK 444
+N + K + N+ I+E L + ++ L+ L + + DL++ DE E++
Sbjct: 607 LNQDSGKSTTALHQENNKIKE---LSQEVERLKLKLKDMKAIEDDLMKTEDEYETLERRY 663
Query: 445 QCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE--LKSKLSTEKA 491
+ + + +LEH K E+ +YK L EK E E L +L E+A
Sbjct: 664 ANERDKAQFLSKELEHVKMELAKYK--LAEKTETSHEQWLFKRLQEEEA 710
>AF514869-1|AAQ08179.1| 1133|Homo sapiens GPBP-interacting protein
130c protein.
Length = 1133
Score = 51.6 bits (118), Expect = 9e-06
Identities = 62/331 (18%), Positives = 131/331 (39%), Gaps = 10/331 (3%)
Query: 170 KTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCAL 229
+ L K+ + + D L+ + LR + +E+ DI + + K + +EL +
Sbjct: 321 RQLQQKLAALSRQIDELEETNRSLR-KAEEELQDIKEKISKGEYGNAGIMAEVEELRKRV 379
Query: 230 SDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTN 289
D+ ++ E+ K R IM L + E +
Sbjct: 380 LDMEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLSKRIMA--LEKLEDAFNKS 437
Query: 290 VERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDI 349
+ L+ LE+ R + L + + E + L K ++K++ T L+ +
Sbjct: 438 KQECYSLKCNLEKERMTTKQLSQELESLKVRIKEL-EAIESRLEKTEFTLKEDLTKLKTL 496
Query: 350 ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEK---KYNDSIEEK 406
+ + + + ++ ++++ KLIE K K +EEK
Sbjct: 497 TVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEK 556
Query: 407 K-TLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRK--T 463
++ + DDL+ L E + DL+ ++ ++ L++ + ++K+ K + + K T
Sbjct: 557 MYSVTKERDDLKNKLKAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTT 616
Query: 464 EIEEYKRLLFEKGEEIDELKSKLSTEKAIKD 494
+ + + E +E++ LK KL KAI+D
Sbjct: 617 ALHQENNKIKELSQEVERLKLKLKDMKAIED 647
Score = 38.7 bits (86), Expect = 0.070
Identities = 65/368 (17%), Positives = 148/368 (40%), Gaps = 24/368 (6%)
Query: 278 RLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQ 337
+L+ AE +++ ++ +LE L+ ++ + T+ Q+L L++
Sbjct: 273 KLALAEARVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDSQNRQLQQKLAALSR 332
Query: 338 SIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH---EMNLNIAKLIE 394
I + + A E+LQ +A +++++ +M +LI+
Sbjct: 333 QIDELEETNRSLRKAEEELQDIKEKISKGEYG-NAGIMAEVEELRKRVLDMEGKDEELIK 391
Query: 395 IEKKYNDSIE--EKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELE 452
+E++ D + E++TLQ D + ++ + R+ L + D + ++ LE
Sbjct: 392 MEEQCRDLNKRLERETLQSK--DFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLE 449
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS-TEKAIKDIXXXXXXXXXXXXXXXX 511
+ + E+E K + +E++ ++S+L TE +K+
Sbjct: 450 KERMTTKQLSQELESLKVRI----KELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERK 505
Query: 512 XXXXXXXXRESQMKSYYEELMNLKNQITQLREF------GAFDNLNDVGNM---INQQRD 562
E ++++ +L +N++T + E A + DV + ++RD
Sbjct: 506 TMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERD 565
Query: 563 KLFELTKRQEEYDEKLQTKENEIKRLVESM--TEQEHVLNKKEKEIKMLNEKEEEHMNII 620
L K +EE L ++ N +K ++S+ E++ + NK ++ + N I
Sbjct: 566 DLKNKLKAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTTALHQENNKI 625
Query: 621 NLLHNKLE 628
L ++E
Sbjct: 626 KELSQEVE 633
Score = 37.5 bits (83), Expect = 0.16
Identities = 70/349 (20%), Positives = 139/349 (39%), Gaps = 29/349 (8%)
Query: 149 KRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKS---SLDQLRTEFLKEINDII 205
K +E+I E K + +TL + K+F E + L +L++L F K +
Sbjct: 385 KDEELIKMEEQCRDLNKRLERETL--QSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECY 442
Query: 206 DCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXX 265
L+ N + ++ TK+LS L L + E+ + I S + +
Sbjct: 443 S-LKCNLEKE---RMTTKQLSQELESLKVRIKEL-EAIESRLEKTEFTLKEDLTKLKTLT 497
Query: 266 XXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXX 325
M ++L + E +L+ + L+ +++ ++ +
Sbjct: 498 VMFVDERKTMSEKLKKTEDKLQA-------ASSQLQVEQNKVTTVTEKLIEETKRALKSK 550
Query: 326 EDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKD-MKHE 384
D ++++ +T+ D L+ A E+ + S KD +K++
Sbjct: 551 TDVEEKMYSVTKERDDLKNKLK----AEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNK 606
Query: 385 MNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETK 444
+N + K + N+ I+E L + ++ L+ L + + DL++ DE E++
Sbjct: 607 LNQDSGKSTTALHQENNKIKE---LSQEVERLKLKLKDMKAIEDDLMKTEDEYETLERRY 663
Query: 445 QCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE--LKSKLSTEKA 491
+ + + +LEH K E+ +YK L EK E E L +L E+A
Sbjct: 664 ANERDKAQFLSKELEHVKMELAKYK--LAEKTETSHEQWLFKRLQEEEA 710
>AF514868-1|AAQ08178.1| 1133|Homo sapiens GPBP-interacting protein
130b protein.
Length = 1133
Score = 51.6 bits (118), Expect = 9e-06
Identities = 62/331 (18%), Positives = 131/331 (39%), Gaps = 10/331 (3%)
Query: 170 KTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCAL 229
+ L K+ + + D L+ + LR + +E+ DI + + K + +EL +
Sbjct: 321 RQLQQKLAALSRQIDELEETNRSLR-KAEEELQDIKEKISKGEYGNAGIMAEVEELRKRV 379
Query: 230 SDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTN 289
D+ ++ E+ K R IM L + E +
Sbjct: 380 LDMEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLSKRIMA--LEKLEDAFNKS 437
Query: 290 VERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDI 349
+ L+ LE+ R + L + + E + L K ++K++ T L+ +
Sbjct: 438 KQECYSLKCNLEKERMTTKQLSQELESLKVRIKEL-EAIESRLEKTEFTLKEDLTKLKTL 496
Query: 350 ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEK---KYNDSIEEK 406
+ + + + ++ ++++ KLIE K K +EEK
Sbjct: 497 TVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEK 556
Query: 407 K-TLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRK--T 463
++ + DDL+ L E + DL+ ++ ++ L++ + ++K+ K + + K T
Sbjct: 557 MYSVTKERDDLKNKLKAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTT 616
Query: 464 EIEEYKRLLFEKGEEIDELKSKLSTEKAIKD 494
+ + + E +E++ LK KL KAI+D
Sbjct: 617 ALHQENNKIKELSQEVERLKLKLKDMKAIED 647
Score = 38.7 bits (86), Expect = 0.070
Identities = 65/368 (17%), Positives = 148/368 (40%), Gaps = 24/368 (6%)
Query: 278 RLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQ 337
+L+ AE +++ ++ +LE L+ ++ + T+ Q+L L++
Sbjct: 273 KLALAEARVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDSQNRQLQQKLAALSR 332
Query: 338 SIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH---EMNLNIAKLIE 394
I + + A E+LQ +A +++++ +M +LI+
Sbjct: 333 QIDELEETNRSLRKAEEELQDIKEKISKGEYG-NAGIMAEVEELRKRVLDMEGKDEELIK 391
Query: 395 IEKKYNDSIE--EKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELE 452
+E++ D + E++TLQ D + ++ + R+ L + D + ++ LE
Sbjct: 392 MEEQCRDLNKRLERETLQSK--DFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLE 449
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS-TEKAIKDIXXXXXXXXXXXXXXXX 511
+ + E+E K + +E++ ++S+L TE +K+
Sbjct: 450 KERMTTKQLSQELESLKVRI----KELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERK 505
Query: 512 XXXXXXXXRESQMKSYYEELMNLKNQITQLREF------GAFDNLNDVGNM---INQQRD 562
E ++++ +L +N++T + E A + DV + ++RD
Sbjct: 506 TMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERD 565
Query: 563 KLFELTKRQEEYDEKLQTKENEIKRLVESM--TEQEHVLNKKEKEIKMLNEKEEEHMNII 620
L K +EE L ++ N +K ++S+ E++ + NK ++ + N I
Sbjct: 566 DLKNKLKAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTTALHQENNKI 625
Query: 621 NLLHNKLE 628
L ++E
Sbjct: 626 KELSQEVE 633
Score = 37.5 bits (83), Expect = 0.16
Identities = 70/349 (20%), Positives = 139/349 (39%), Gaps = 29/349 (8%)
Query: 149 KRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKS---SLDQLRTEFLKEINDII 205
K +E+I E K + +TL + K+F E + L +L++L F K +
Sbjct: 385 KDEELIKMEEQCRDLNKRLERETL--QSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECY 442
Query: 206 DCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXX 265
L+ N + ++ TK+LS L L + E+ + I S + +
Sbjct: 443 S-LKCNLEKE---RMTTKQLSQELESLKVRIKEL-EAIESRLEKTEFTLKEDLTKLKTLT 497
Query: 266 XXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXX 325
M ++L + E +L+ + L+ +++ ++ +
Sbjct: 498 VMFVDERKTMSEKLKKTEDKLQA-------ASSQLQVEQNKVTTVTEKLIEETKRALKSK 550
Query: 326 EDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKD-MKHE 384
D ++++ +T+ D L+ A E+ + S KD +K++
Sbjct: 551 TDVEEKMYSVTKERDDLKNKLK----AEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNK 606
Query: 385 MNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETK 444
+N + K + N+ I+E L + ++ L+ L + + DL++ DE E++
Sbjct: 607 LNQDSGKSTTALHQENNKIKE---LSQEVERLKLKLKDMKAIEDDLMKTEDEYETLERRY 663
Query: 445 QCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE--LKSKLSTEKA 491
+ + + +LEH K E+ +YK L EK E E L +L E+A
Sbjct: 664 ANERDKAQFLSKELEHVKMELAKYK--LAEKTETSHEQWLFKRLQEEEA 710
>AF514867-1|AAQ08177.1| 1135|Homo sapiens GPBP-interacting protein
130a protein.
Length = 1135
Score = 51.6 bits (118), Expect = 9e-06
Identities = 62/331 (18%), Positives = 131/331 (39%), Gaps = 10/331 (3%)
Query: 170 KTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCAL 229
+ L K+ + + D L+ + LR + +E+ DI + + K + +EL +
Sbjct: 321 RQLQQKLAALSRQIDELEETNRSLR-KAEEELQDIKEKISKGEYGNAGIMAEVEELRKRV 379
Query: 230 SDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTN 289
D+ ++ E+ K R IM L + E +
Sbjct: 380 LDMEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLSKRIMA--LEKLEDAFNKS 437
Query: 290 VERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDI 349
+ L+ LE+ R + L + + E + L K ++K++ T L+ +
Sbjct: 438 KQECYSLKCNLEKERMTTKQLSQELESLKVRIKEL-EAIESRLEKTEFTLKEDLTKLKTL 496
Query: 350 ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEK---KYNDSIEEK 406
+ + + + ++ ++++ KLIE K K +EEK
Sbjct: 497 TVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEK 556
Query: 407 K-TLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRK--T 463
++ + DDL+ L E + DL+ ++ ++ L++ + ++K+ K + + K T
Sbjct: 557 MYSVTKERDDLKNKLKAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTT 616
Query: 464 EIEEYKRLLFEKGEEIDELKSKLSTEKAIKD 494
+ + + E +E++ LK KL KAI+D
Sbjct: 617 ALHQENNKIKELSQEVERLKLKLKDMKAIED 647
Score = 38.7 bits (86), Expect = 0.070
Identities = 65/368 (17%), Positives = 148/368 (40%), Gaps = 24/368 (6%)
Query: 278 RLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQ 337
+L+ AE +++ ++ +LE L+ ++ + T+ Q+L L++
Sbjct: 273 KLALAEARVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDSQNRQLQQKLAALSR 332
Query: 338 SIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH---EMNLNIAKLIE 394
I + + A E+LQ +A +++++ +M +LI+
Sbjct: 333 QIDELEETNRSLRKAEEELQDIKEKISKGEYG-NAGIMAEVEELRKRVLDMEGKDEELIK 391
Query: 395 IEKKYNDSIE--EKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELE 452
+E++ D + E++TLQ D + ++ + R+ L + D + ++ LE
Sbjct: 392 MEEQCRDLNKRLERETLQSK--DFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLE 449
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS-TEKAIKDIXXXXXXXXXXXXXXXX 511
+ + E+E K + +E++ ++S+L TE +K+
Sbjct: 450 KERMTTKQLSQELESLKVRI----KELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERK 505
Query: 512 XXXXXXXXRESQMKSYYEELMNLKNQITQLREF------GAFDNLNDVGNM---INQQRD 562
E ++++ +L +N++T + E A + DV + ++RD
Sbjct: 506 TMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERD 565
Query: 563 KLFELTKRQEEYDEKLQTKENEIKRLVESM--TEQEHVLNKKEKEIKMLNEKEEEHMNII 620
L K +EE L ++ N +K ++S+ E++ + NK ++ + N I
Sbjct: 566 DLKNKLKAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTTALHQENNKI 625
Query: 621 NLLHNKLE 628
L ++E
Sbjct: 626 KELSQEVE 633
Score = 37.5 bits (83), Expect = 0.16
Identities = 70/349 (20%), Positives = 139/349 (39%), Gaps = 29/349 (8%)
Query: 149 KRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKS---SLDQLRTEFLKEINDII 205
K +E+I E K + +TL + K+F E + L +L++L F K +
Sbjct: 385 KDEELIKMEEQCRDLNKRLERETL--QSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECY 442
Query: 206 DCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXX 265
L+ N + ++ TK+LS L L + E+ + I S + +
Sbjct: 443 S-LKCNLEKE---RMTTKQLSQELESLKVRIKEL-EAIESRLEKTEFTLKEDLTKLKTLT 497
Query: 266 XXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXX 325
M ++L + E +L+ + L+ +++ ++ +
Sbjct: 498 VMFVDERKTMSEKLKKTEDKLQA-------ASSQLQVEQNKVTTVTEKLIEETKRALKSK 550
Query: 326 EDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKD-MKHE 384
D ++++ +T+ D L+ A E+ + S KD +K++
Sbjct: 551 TDVEEKMYSVTKERDDLKNKLK----AEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNK 606
Query: 385 MNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETK 444
+N + K + N+ I+E L + ++ L+ L + + DL++ DE E++
Sbjct: 607 LNQDSGKSTTALHQENNKIKE---LSQEVERLKLKLKDMKAIEDDLMKTEDEYETLERRY 663
Query: 445 QCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE--LKSKLSTEKA 491
+ + + +LEH K E+ +YK L EK E E L +L E+A
Sbjct: 664 ANERDKAQFLSKELEHVKMELAKYK--LAEKTETSHEQWLFKRLQEEEA 710
>AF329092-1|AAN16206.1| 764|Homo sapiens GPBP-interacting protein
90 protein.
Length = 764
Score = 51.6 bits (118), Expect = 9e-06
Identities = 62/331 (18%), Positives = 131/331 (39%), Gaps = 10/331 (3%)
Query: 170 KTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCAL 229
+ L K+ + + D L+ + LR + +E+ DI + + K + +EL +
Sbjct: 321 RQLQQKLAALSRQIDELEETNRSLR-KAEEELQDIKEKISKGEYGNAGIMAEVEELRKRV 379
Query: 230 SDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTN 289
D+ ++ E+ K R IM L + E +
Sbjct: 380 LDMEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLSKRIMA--LEKLEDAFNKS 437
Query: 290 VERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDI 349
+ L+ LE+ R + L + + E + L K ++K++ T L+ +
Sbjct: 438 KQECYSLKCNLEKERMTTKQLSQELESLKVRIKEL-EAIESRLEKTEFTLKEDLTKLKTL 496
Query: 350 ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEK---KYNDSIEEK 406
+ + + + ++ ++++ KLIE K K +EEK
Sbjct: 497 TVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEK 556
Query: 407 K-TLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRK--T 463
++ + DDL+ L E + DL+ ++ ++ L++ + ++K+ K + + K T
Sbjct: 557 MYSVTKERDDLKNKLKAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTT 616
Query: 464 EIEEYKRLLFEKGEEIDELKSKLSTEKAIKD 494
+ + + E +E++ LK KL KAI+D
Sbjct: 617 ALHQENNKIKELSQEVERLKLKLKDMKAIED 647
Score = 38.7 bits (86), Expect = 0.070
Identities = 65/368 (17%), Positives = 148/368 (40%), Gaps = 24/368 (6%)
Query: 278 RLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQ 337
+L+ AE +++ ++ +LE L+ ++ + T+ Q+L L++
Sbjct: 273 KLALAEARVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDSQNRQLQQKLAALSR 332
Query: 338 SIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH---EMNLNIAKLIE 394
I + + A E+LQ +A +++++ +M +LI+
Sbjct: 333 QIDELEETNRSLRKAEEELQDIKEKISKGEYG-NAGIMAEVEELRKRVLDMEGKDEELIK 391
Query: 395 IEKKYNDSIE--EKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELE 452
+E++ D + E++TLQ D + ++ + R+ L + D + ++ LE
Sbjct: 392 MEEQCRDLNKRLERETLQSK--DFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLE 449
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS-TEKAIKDIXXXXXXXXXXXXXXXX 511
+ + E+E K + +E++ ++S+L TE +K+
Sbjct: 450 KERMTTKQLSQELESLKVRI----KELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERK 505
Query: 512 XXXXXXXXRESQMKSYYEELMNLKNQITQLREF------GAFDNLNDVGNM---INQQRD 562
E ++++ +L +N++T + E A + DV + ++RD
Sbjct: 506 TMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERD 565
Query: 563 KLFELTKRQEEYDEKLQTKENEIKRLVESM--TEQEHVLNKKEKEIKMLNEKEEEHMNII 620
L K +EE L ++ N +K ++S+ E++ + NK ++ + N I
Sbjct: 566 DLKNKLKAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTTALHQENNKI 625
Query: 621 NLLHNKLE 628
L ++E
Sbjct: 626 KELSQEVE 633
Score = 37.5 bits (83), Expect = 0.16
Identities = 70/349 (20%), Positives = 139/349 (39%), Gaps = 29/349 (8%)
Query: 149 KRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKS---SLDQLRTEFLKEINDII 205
K +E+I E K + +TL + K+F E + L +L++L F K +
Sbjct: 385 KDEELIKMEEQCRDLNKRLERETL--QSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECY 442
Query: 206 DCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXX 265
L+ N + ++ TK+LS L L + E+ + I S + +
Sbjct: 443 S-LKCNLEKE---RMTTKQLSQELESLKVRIKEL-EAIESRLEKTEFTLKEDLTKLKTLT 497
Query: 266 XXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXX 325
M ++L + E +L+ + L+ +++ ++ +
Sbjct: 498 VMFVDERKTMSEKLKKTEDKLQA-------ASSQLQVEQNKVTTVTEKLIEETKRALKSK 550
Query: 326 EDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKD-MKHE 384
D ++++ +T+ D L+ A E+ + S KD +K++
Sbjct: 551 TDVEEKMYSVTKERDDLKNKLK----AEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNK 606
Query: 385 MNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETK 444
+N + K + N+ I+E L + ++ L+ L + + DL++ DE E++
Sbjct: 607 LNQDSGKSTTALHQENNKIKE---LSQEVERLKLKLKDMKAIEDDLMKTEDEYETLERRY 663
Query: 445 QCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE--LKSKLSTEKA 491
+ + + +LEH K E+ +YK L EK E E L +L E+A
Sbjct: 664 ANERDKAQFLSKELEHVKMELAKYK--LAEKTETSHEQWLFKRLQEEEA 710
>BC128577-1|AAI28578.1| 934|Homo sapiens RRBP1 protein protein.
Length = 934
Score = 51.2 bits (117), Expect = 1e-05
Identities = 44/221 (19%), Positives = 98/221 (44%), Gaps = 13/221 (5%)
Query: 278 RLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQ 337
RL E Q+ + ++L A+EQ + ++ L + ++L+ LTQ
Sbjct: 512 RLKELESQVSGLEKEAIELREAVEQQKVKNNDLREKNWKAMEALATAEQACKEKLHSLTQ 571
Query: 338 SIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAK------ 391
+ +++ L + + +++ +Y + ++D+K E + K
Sbjct: 572 AKEESEKQL--CLIEAQTMEALLALLPELSVLAQQNYTEWLQDLK-EKGPTLLKHPPAPA 628
Query: 392 --LIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETK-QCVQ 448
++ K ++ E + TLQ D R+ L E+E ++DL + ++E+E + K +
Sbjct: 629 EPSSDLASKLREAEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEEQVWRAKVGAAE 688
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
+EL+ ++ ++H + +E+ K L E +++ E L E
Sbjct: 689 EELQKSRVTVKHLEEIVEKLKGEL-ESSDQVREHTLHLEAE 728
>BC000099-1|AAH00099.4| 655|Homo sapiens RRBP1 protein protein.
Length = 655
Score = 51.2 bits (117), Expect = 1e-05
Identities = 44/221 (19%), Positives = 98/221 (44%), Gaps = 13/221 (5%)
Query: 278 RLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQ 337
RL E Q+ + ++L A+EQ + ++ L + ++L+ LTQ
Sbjct: 233 RLKELESQVSGLEKEAIELREAVEQQKVKNNDLREKNWKAMEALATAEQACKEKLHSLTQ 292
Query: 338 SIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAK------ 391
+ +++ L + + +++ +Y + ++D+K E + K
Sbjct: 293 AKEESEKQL--CLIEAQTMEALLALLPELSVLAQQNYTEWLQDLK-EKGPTLLKHPPAPA 349
Query: 392 --LIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETK-QCVQ 448
++ K ++ E + TLQ D R+ L E+E ++DL + ++E+E + K +
Sbjct: 350 EPSSDLASKLREAEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEEQVWRAKVGAAE 409
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
+EL+ ++ ++H + +E+ K L E +++ E L E
Sbjct: 410 EELQKSRVTVKHLEEIVEKLKGEL-ESSDQVREHTLHLEAE 449
>AL157400-6|CAI16830.1| 1820|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 1820
Score = 51.2 bits (117), Expect = 1e-05
Identities = 102/507 (20%), Positives = 196/507 (38%), Gaps = 49/507 (9%)
Query: 132 LLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLL----- 186
LL I N L ++ EE K+I+++ + L EK TL+ ++++ + D+
Sbjct: 891 LLTIENELKNEKEEKAELNKQIVHFQQELSLSEK--KNLTLSKEVQQIQSNYDIAIAELH 948
Query: 187 --KSSLDQLRTEFLKEINDIIDCLRKNANETMALQL-RTK--ELSCALSDLNTQNAEMR- 240
KS + + +K N+I R N ++L TK EL S N ++
Sbjct: 949 VQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELRTLDSVSQISNIDLLN 1008
Query: 241 -KQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAA 299
+ + +G N +++ E+ +++E + +
Sbjct: 1009 LRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQE--PNRENSFHSSIEAIWEECKE 1066
Query: 300 LEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLED-----IALARE 354
+ +A S+ + + + E N+L + N L I +E
Sbjct: 1067 IVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKE 1126
Query: 355 KLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENID 414
+LQ +++ ++ + AK+ E+E +E +K +
Sbjct: 1127 ELQEKNVTLDVQIQHVVEG-KRALSELTQGVTCYKAKIKELET----ILETQKVECSHSA 1181
Query: 415 DLRTDLLESELRVKDLVRELDE-----KESILETKQCVQKELESTKTDLEHRKTEIEEYK 469
L D+LE E + L R L E ++S+ TK KEL+ K ++ +++ K
Sbjct: 1182 KLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELK-LKEEITQLTNNLQDMK 1240
Query: 470 RLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYE 529
LL K EE E ++ TEK +++ +E E
Sbjct: 1241 HLLQLKEEE--EETNRQETEKLKEEL--------SASSARTQNLKADLQRKEEDYADLKE 1290
Query: 530 ELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLV 589
+L + K QI Q+++ + D ++ R K+ EL K++ + ++L K+ I++L
Sbjct: 1291 KLTDAKKQIKQVQK--EVSVMRDEDKLL---RIKINELEKKKNQCSQELDMKQRTIQQLK 1345
Query: 590 ESMTEQ--EHVLNKKEKEIKMLNEKEE 614
E + Q E + + E+ K LN KE+
Sbjct: 1346 EQLNNQKVEEAIQQYERACKDLNVKEK 1372
Score = 48.4 bits (110), Expect = 9e-05
Identities = 49/257 (19%), Positives = 108/257 (42%), Gaps = 8/257 (3%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD 435
+++K+ + + ++ ++ K EE L N+ D++ LL+ + ++ R+
Sbjct: 1199 RNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMK-HLLQLKEEEEETNRQ-- 1255
Query: 436 EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDI 495
E E + E ++ K DL+ ++ + + K L + ++I +++ ++S ++D
Sbjct: 1256 ETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSV---MRDE 1312
Query: 496 XXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGN 555
++ ++ E+L N K + + A +LN
Sbjct: 1313 DKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEK 1372
Query: 556 MINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEE 615
+I R L E + Q E D+ L+ K E++RL + + + N + E K +E
Sbjct: 1373 IIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCN--DLETKNNQRSNKE 1430
Query: 616 HMNIINLLHNKLELRNE 632
H N ++L L++E
Sbjct: 1431 HENNTDVLGKLTNLQDE 1447
Score = 41.1 bits (92), Expect = 0.013
Identities = 45/262 (17%), Positives = 107/262 (40%), Gaps = 6/262 (2%)
Query: 371 SASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDL 430
+A +K E+ +LI+ +++ E +L + ++ ++ R+K+L
Sbjct: 710 TACLELKFNQIKAELAKTKGELIKTKEELKKRENESDSLIQELETSNKKIITQNQRIKEL 769
Query: 431 VRELDEKESILETKQCVQKELEST--KTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLST 488
+ +D+KE + Q ++ +E+T D + I K + E E + KSK+ +
Sbjct: 770 INIIDQKEDTINEFQNLKSHMENTFKCNDKADTSSLIINNKLICNETVEVPKDSKSKICS 829
Query: 489 E-KAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRES-QMKSYYEELMNLKNQITQLREFGA 546
E K + + ++S +++ E+ +++ + Q G
Sbjct: 830 ERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNIAEIEDIR--VLQENNEGL 887
Query: 547 FDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEI 606
L + N + ++++ EL K+ + ++L E + L + + + + + E+
Sbjct: 888 RAFLLTIENELKNEKEEKAELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSNYDIAIAEL 947
Query: 607 KMLNEKEEEHMNIINLLHNKLE 628
+ K +E I L N++E
Sbjct: 948 HVQKSKNQEQEEKIMKLSNEIE 969
Score = 38.7 bits (86), Expect = 0.070
Identities = 69/366 (18%), Positives = 153/366 (41%), Gaps = 30/366 (8%)
Query: 1 MKQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQN 60
+K+EE E + +T E L E+ +++ S + LK Q K + K++L D +
Sbjct: 1245 LKEEEEETNRQET-----EKLKEE--LSASSARTQNLKADLQRKEEDYADLKEKLTDAKK 1297
Query: 61 QVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHST 120
Q+ ++ + + KLL K+N ++ + + QL + +E +
Sbjct: 1298 QIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAI 1357
Query: 121 LD-NKVTFDVN---KLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKI 176
+ D+N K++ +++ E+T ++ +++ E+ + + + ++T+ K
Sbjct: 1358 QQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVL---EAKLEEVERLATELEKWKE 1414
Query: 177 K--EFNAENDLLKSSLDQLRTEFLKEINDIIDCLRK-----NANETMALQLRTKELSCAL 229
K + +N+ + + T+ L ++ ++ D L++ NA+ L+ + ++ A
Sbjct: 1415 KCNDLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAK 1474
Query: 230 SDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIM---KDRLSRA-EHQ 285
N +N EM+K ++ D R + +N +D+L A E Q
Sbjct: 1475 EAENIRNKEMKK--YAEDRERFFKQQNEMEILTAQLTEKDSDLQKWREERDQLVAALEIQ 1532
Query: 286 LKTNVERVVQLEAALEQAR---SESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDN 342
LK + VQ + +EQ + SE+ +E + + + L+ S + +
Sbjct: 1533 LKALISSNVQKDNEIEQLKRIISETSKIETQIMDIKPKRISSADPDKLQTEPLSTSFEIS 1592
Query: 343 TTHLED 348
+ED
Sbjct: 1593 RNKIED 1598
>AL157400-5|CAI16831.1| 1780|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 1780
Score = 51.2 bits (117), Expect = 1e-05
Identities = 102/507 (20%), Positives = 196/507 (38%), Gaps = 49/507 (9%)
Query: 132 LLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLL----- 186
LL I N L ++ EE K+I+++ + L EK TL+ ++++ + D+
Sbjct: 851 LLTIENELKNEKEEKAELNKQIVHFQQELSLSEK--KNLTLSKEVQQIQSNYDIAIAELH 908
Query: 187 --KSSLDQLRTEFLKEINDIIDCLRKNANETMALQL-RTK--ELSCALSDLNTQNAEMR- 240
KS + + +K N+I R N ++L TK EL S N ++
Sbjct: 909 VQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELRTLDSVSQISNIDLLN 968
Query: 241 -KQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAA 299
+ + +G N +++ E+ +++E + +
Sbjct: 969 LRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQE--PNRENSFHSSIEAIWEECKE 1026
Query: 300 LEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLED-----IALARE 354
+ +A S+ + + + E N+L + N L I +E
Sbjct: 1027 IVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKE 1086
Query: 355 KLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENID 414
+LQ +++ ++ + AK+ E+E +E +K +
Sbjct: 1087 ELQEKNVTLDVQIQHVVEG-KRALSELTQGVTCYKAKIKELET----ILETQKVECSHSA 1141
Query: 415 DLRTDLLESELRVKDLVRELDE-----KESILETKQCVQKELESTKTDLEHRKTEIEEYK 469
L D+LE E + L R L E ++S+ TK KEL+ K ++ +++ K
Sbjct: 1142 KLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELK-LKEEITQLTNNLQDMK 1200
Query: 470 RLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYE 529
LL K EE E ++ TEK +++ +E E
Sbjct: 1201 HLLQLKEEE--EETNRQETEKLKEEL--------SASSARTQNLKADLQRKEEDYADLKE 1250
Query: 530 ELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLV 589
+L + K QI Q+++ + D ++ R K+ EL K++ + ++L K+ I++L
Sbjct: 1251 KLTDAKKQIKQVQK--EVSVMRDEDKLL---RIKINELEKKKNQCSQELDMKQRTIQQLK 1305
Query: 590 ESMTEQ--EHVLNKKEKEIKMLNEKEE 614
E + Q E + + E+ K LN KE+
Sbjct: 1306 EQLNNQKVEEAIQQYERACKDLNVKEK 1332
Score = 48.4 bits (110), Expect = 9e-05
Identities = 49/257 (19%), Positives = 108/257 (42%), Gaps = 8/257 (3%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD 435
+++K+ + + ++ ++ K EE L N+ D++ LL+ + ++ R+
Sbjct: 1159 RNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMK-HLLQLKEEEEETNRQ-- 1215
Query: 436 EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDI 495
E E + E ++ K DL+ ++ + + K L + ++I +++ ++S ++D
Sbjct: 1216 ETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSV---MRDE 1272
Query: 496 XXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGN 555
++ ++ E+L N K + + A +LN
Sbjct: 1273 DKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEK 1332
Query: 556 MINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEE 615
+I R L E + Q E D+ L+ K E++RL + + + N + E K +E
Sbjct: 1333 IIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCN--DLETKNNQRSNKE 1390
Query: 616 HMNIINLLHNKLELRNE 632
H N ++L L++E
Sbjct: 1391 HENNTDVLGKLTNLQDE 1407
Score = 41.1 bits (92), Expect = 0.013
Identities = 45/262 (17%), Positives = 107/262 (40%), Gaps = 6/262 (2%)
Query: 371 SASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDL 430
+A +K E+ +LI+ +++ E +L + ++ ++ R+K+L
Sbjct: 670 TACLELKFNQIKAELAKTKGELIKTKEELKKRENESDSLIQELETSNKKIITQNQRIKEL 729
Query: 431 VRELDEKESILETKQCVQKELEST--KTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLST 488
+ +D+KE + Q ++ +E+T D + I K + E E + KSK+ +
Sbjct: 730 INIIDQKEDTINEFQNLKSHMENTFKCNDKADTSSLIINNKLICNETVEVPKDSKSKICS 789
Query: 489 E-KAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRES-QMKSYYEELMNLKNQITQLREFGA 546
E K + + ++S +++ E+ +++ + Q G
Sbjct: 790 ERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNIAEIEDIR--VLQENNEGL 847
Query: 547 FDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEI 606
L + N + ++++ EL K+ + ++L E + L + + + + + E+
Sbjct: 848 RAFLLTIENELKNEKEEKAELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSNYDIAIAEL 907
Query: 607 KMLNEKEEEHMNIINLLHNKLE 628
+ K +E I L N++E
Sbjct: 908 HVQKSKNQEQEEKIMKLSNEIE 929
Score = 38.7 bits (86), Expect = 0.070
Identities = 69/366 (18%), Positives = 153/366 (41%), Gaps = 30/366 (8%)
Query: 1 MKQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQN 60
+K+EE E + +T E L E+ +++ S + LK Q K + K++L D +
Sbjct: 1205 LKEEEEETNRQET-----EKLKEE--LSASSARTQNLKADLQRKEEDYADLKEKLTDAKK 1257
Query: 61 QVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHST 120
Q+ ++ + + KLL K+N ++ + + QL + +E +
Sbjct: 1258 QIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAI 1317
Query: 121 LD-NKVTFDVN---KLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKI 176
+ D+N K++ +++ E+T ++ +++ E+ + + + ++T+ K
Sbjct: 1318 QQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVL---EAKLEEVERLATELEKWKE 1374
Query: 177 K--EFNAENDLLKSSLDQLRTEFLKEINDIIDCLRK-----NANETMALQLRTKELSCAL 229
K + +N+ + + T+ L ++ ++ D L++ NA+ L+ + ++ A
Sbjct: 1375 KCNDLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAK 1434
Query: 230 SDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIM---KDRLSRA-EHQ 285
N +N EM+K ++ D R + +N +D+L A E Q
Sbjct: 1435 EAENIRNKEMKK--YAEDRERFFKQQNEMEILTAQLTEKDSDLQKWREERDQLVAALEIQ 1492
Query: 286 LKTNVERVVQLEAALEQAR---SESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDN 342
LK + VQ + +EQ + SE+ +E + + + L+ S + +
Sbjct: 1493 LKALISSNVQKDNEIEQLKRIISETSKIETQIMDIKPKRISSADPDKLQTEPLSTSFEIS 1552
Query: 343 TTHLED 348
+ED
Sbjct: 1553 RNKIED 1558
>AL157389-3|CAI12887.1| 1780|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 1780
Score = 51.2 bits (117), Expect = 1e-05
Identities = 102/507 (20%), Positives = 196/507 (38%), Gaps = 49/507 (9%)
Query: 132 LLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLL----- 186
LL I N L ++ EE K+I+++ + L EK TL+ ++++ + D+
Sbjct: 851 LLTIENELKNEKEEKAELNKQIVHFQQELSLSEK--KNLTLSKEVQQIQSNYDIAIAELH 908
Query: 187 --KSSLDQLRTEFLKEINDIIDCLRKNANETMALQL-RTK--ELSCALSDLNTQNAEMR- 240
KS + + +K N+I R N ++L TK EL S N ++
Sbjct: 909 VQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELRTLDSVSQISNIDLLN 968
Query: 241 -KQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAA 299
+ + +G N +++ E+ +++E + +
Sbjct: 969 LRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQE--PNRENSFHSSIEAIWEECKE 1026
Query: 300 LEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLED-----IALARE 354
+ +A S+ + + + E N+L + N L I +E
Sbjct: 1027 IVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKE 1086
Query: 355 KLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENID 414
+LQ +++ ++ + AK+ E+E +E +K +
Sbjct: 1087 ELQEKNVTLDVQIQHVVEG-KRALSELTQGVTCYKAKIKELET----ILETQKVECSHSA 1141
Query: 415 DLRTDLLESELRVKDLVRELDE-----KESILETKQCVQKELESTKTDLEHRKTEIEEYK 469
L D+LE E + L R L E ++S+ TK KEL+ K ++ +++ K
Sbjct: 1142 KLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELK-LKEEITQLTNNLQDMK 1200
Query: 470 RLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYE 529
LL K EE E ++ TEK +++ +E E
Sbjct: 1201 HLLQLKEEE--EETNRQETEKLKEEL--------SASSARTQNLKADLQRKEEDYADLKE 1250
Query: 530 ELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLV 589
+L + K QI Q+++ + D ++ R K+ EL K++ + ++L K+ I++L
Sbjct: 1251 KLTDAKKQIKQVQK--EVSVMRDEDKLL---RIKINELEKKKNQCSQELDMKQRTIQQLK 1305
Query: 590 ESMTEQ--EHVLNKKEKEIKMLNEKEE 614
E + Q E + + E+ K LN KE+
Sbjct: 1306 EQLNNQKVEEAIQQYERACKDLNVKEK 1332
Score = 48.4 bits (110), Expect = 9e-05
Identities = 49/257 (19%), Positives = 108/257 (42%), Gaps = 8/257 (3%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD 435
+++K+ + + ++ ++ K EE L N+ D++ LL+ + ++ R+
Sbjct: 1159 RNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMK-HLLQLKEEEEETNRQ-- 1215
Query: 436 EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDI 495
E E + E ++ K DL+ ++ + + K L + ++I +++ ++S ++D
Sbjct: 1216 ETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSV---MRDE 1272
Query: 496 XXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGN 555
++ ++ E+L N K + + A +LN
Sbjct: 1273 DKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEK 1332
Query: 556 MINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEE 615
+I R L E + Q E D+ L+ K E++RL + + + N + E K +E
Sbjct: 1333 IIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCN--DLETKNNQRSNKE 1390
Query: 616 HMNIINLLHNKLELRNE 632
H N ++L L++E
Sbjct: 1391 HENNTDVLGKLTNLQDE 1407
Score = 41.1 bits (92), Expect = 0.013
Identities = 45/262 (17%), Positives = 107/262 (40%), Gaps = 6/262 (2%)
Query: 371 SASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDL 430
+A +K E+ +LI+ +++ E +L + ++ ++ R+K+L
Sbjct: 670 TACLELKFNQIKAELAKTKGELIKTKEELKKRENESDSLIQELETSNKKIITQNQRIKEL 729
Query: 431 VRELDEKESILETKQCVQKELEST--KTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLST 488
+ +D+KE + Q ++ +E+T D + I K + E E + KSK+ +
Sbjct: 730 INIIDQKEDTINEFQNLKSHMENTFKCNDKADTSSLIINNKLICNETVEVPKDSKSKICS 789
Query: 489 E-KAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRES-QMKSYYEELMNLKNQITQLREFGA 546
E K + + ++S +++ E+ +++ + Q G
Sbjct: 790 ERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNIAEIEDIR--VLQENNEGL 847
Query: 547 FDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEI 606
L + N + ++++ EL K+ + ++L E + L + + + + + E+
Sbjct: 848 RAFLLTIENELKNEKEEKAELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSNYDIAIAEL 907
Query: 607 KMLNEKEEEHMNIINLLHNKLE 628
+ K +E I L N++E
Sbjct: 908 HVQKSKNQEQEEKIMKLSNEIE 929
Score = 38.7 bits (86), Expect = 0.070
Identities = 69/366 (18%), Positives = 153/366 (41%), Gaps = 30/366 (8%)
Query: 1 MKQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQN 60
+K+EE E + +T E L E+ +++ S + LK Q K + K++L D +
Sbjct: 1205 LKEEEEETNRQET-----EKLKEE--LSASSARTQNLKADLQRKEEDYADLKEKLTDAKK 1257
Query: 61 QVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHST 120
Q+ ++ + + KLL K+N ++ + + QL + +E +
Sbjct: 1258 QIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAI 1317
Query: 121 LD-NKVTFDVN---KLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKI 176
+ D+N K++ +++ E+T ++ +++ E+ + + + ++T+ K
Sbjct: 1318 QQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVL---EAKLEEVERLATELEKWKE 1374
Query: 177 K--EFNAENDLLKSSLDQLRTEFLKEINDIIDCLRK-----NANETMALQLRTKELSCAL 229
K + +N+ + + T+ L ++ ++ D L++ NA+ L+ + ++ A
Sbjct: 1375 KCNDLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAK 1434
Query: 230 SDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIM---KDRLSRA-EHQ 285
N +N EM+K ++ D R + +N +D+L A E Q
Sbjct: 1435 EAENIRNKEMKK--YAEDRERFFKQQNEMEILTAQLTEKDSDLQKWREERDQLVAALEIQ 1492
Query: 286 LKTNVERVVQLEAALEQAR---SESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDN 342
LK + VQ + +EQ + SE+ +E + + + L+ S + +
Sbjct: 1493 LKALISSNVQKDNEIEQLKRIISETSKIETQIMDIKPKRISSADPDKLQTEPLSTSFEIS 1552
Query: 343 TTHLED 348
+ED
Sbjct: 1553 RNKIED 1558
>AL157389-2|CAI12886.1| 1820|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 1820
Score = 51.2 bits (117), Expect = 1e-05
Identities = 102/507 (20%), Positives = 196/507 (38%), Gaps = 49/507 (9%)
Query: 132 LLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLL----- 186
LL I N L ++ EE K+I+++ + L EK TL+ ++++ + D+
Sbjct: 891 LLTIENELKNEKEEKAELNKQIVHFQQELSLSEK--KNLTLSKEVQQIQSNYDIAIAELH 948
Query: 187 --KSSLDQLRTEFLKEINDIIDCLRKNANETMALQL-RTK--ELSCALSDLNTQNAEMR- 240
KS + + +K N+I R N ++L TK EL S N ++
Sbjct: 949 VQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELRTLDSVSQISNIDLLN 1008
Query: 241 -KQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAA 299
+ + +G N +++ E+ +++E + +
Sbjct: 1009 LRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQE--PNRENSFHSSIEAIWEECKE 1066
Query: 300 LEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLED-----IALARE 354
+ +A S+ + + + E N+L + N L I +E
Sbjct: 1067 IVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKE 1126
Query: 355 KLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENID 414
+LQ +++ ++ + AK+ E+E +E +K +
Sbjct: 1127 ELQEKNVTLDVQIQHVVEG-KRALSELTQGVTCYKAKIKELET----ILETQKVECSHSA 1181
Query: 415 DLRTDLLESELRVKDLVRELDE-----KESILETKQCVQKELESTKTDLEHRKTEIEEYK 469
L D+LE E + L R L E ++S+ TK KEL+ K ++ +++ K
Sbjct: 1182 KLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELK-LKEEITQLTNNLQDMK 1240
Query: 470 RLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYE 529
LL K EE E ++ TEK +++ +E E
Sbjct: 1241 HLLQLKEEE--EETNRQETEKLKEEL--------SASSARTQNLKADLQRKEEDYADLKE 1290
Query: 530 ELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLV 589
+L + K QI Q+++ + D ++ R K+ EL K++ + ++L K+ I++L
Sbjct: 1291 KLTDAKKQIKQVQK--EVSVMRDEDKLL---RIKINELEKKKNQCSQELDMKQRTIQQLK 1345
Query: 590 ESMTEQ--EHVLNKKEKEIKMLNEKEE 614
E + Q E + + E+ K LN KE+
Sbjct: 1346 EQLNNQKVEEAIQQYERACKDLNVKEK 1372
Score = 48.4 bits (110), Expect = 9e-05
Identities = 49/257 (19%), Positives = 108/257 (42%), Gaps = 8/257 (3%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD 435
+++K+ + + ++ ++ K EE L N+ D++ LL+ + ++ R+
Sbjct: 1199 RNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMK-HLLQLKEEEEETNRQ-- 1255
Query: 436 EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDI 495
E E + E ++ K DL+ ++ + + K L + ++I +++ ++S ++D
Sbjct: 1256 ETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSV---MRDE 1312
Query: 496 XXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGN 555
++ ++ E+L N K + + A +LN
Sbjct: 1313 DKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEK 1372
Query: 556 MINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEE 615
+I R L E + Q E D+ L+ K E++RL + + + N + E K +E
Sbjct: 1373 IIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCN--DLETKNNQRSNKE 1430
Query: 616 HMNIINLLHNKLELRNE 632
H N ++L L++E
Sbjct: 1431 HENNTDVLGKLTNLQDE 1447
Score = 41.1 bits (92), Expect = 0.013
Identities = 45/262 (17%), Positives = 107/262 (40%), Gaps = 6/262 (2%)
Query: 371 SASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDL 430
+A +K E+ +LI+ +++ E +L + ++ ++ R+K+L
Sbjct: 710 TACLELKFNQIKAELAKTKGELIKTKEELKKRENESDSLIQELETSNKKIITQNQRIKEL 769
Query: 431 VRELDEKESILETKQCVQKELEST--KTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLST 488
+ +D+KE + Q ++ +E+T D + I K + E E + KSK+ +
Sbjct: 770 INIIDQKEDTINEFQNLKSHMENTFKCNDKADTSSLIINNKLICNETVEVPKDSKSKICS 829
Query: 489 E-KAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRES-QMKSYYEELMNLKNQITQLREFGA 546
E K + + ++S +++ E+ +++ + Q G
Sbjct: 830 ERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNIAEIEDIR--VLQENNEGL 887
Query: 547 FDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEI 606
L + N + ++++ EL K+ + ++L E + L + + + + + E+
Sbjct: 888 RAFLLTIENELKNEKEEKAELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSNYDIAIAEL 947
Query: 607 KMLNEKEEEHMNIINLLHNKLE 628
+ K +E I L N++E
Sbjct: 948 HVQKSKNQEQEEKIMKLSNEIE 969
Score = 38.7 bits (86), Expect = 0.070
Identities = 69/366 (18%), Positives = 153/366 (41%), Gaps = 30/366 (8%)
Query: 1 MKQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQN 60
+K+EE E + +T E L E+ +++ S + LK Q K + K++L D +
Sbjct: 1245 LKEEEEETNRQET-----EKLKEE--LSASSARTQNLKADLQRKEEDYADLKEKLTDAKK 1297
Query: 61 QVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHST 120
Q+ ++ + + KLL K+N ++ + + QL + +E +
Sbjct: 1298 QIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAI 1357
Query: 121 LD-NKVTFDVN---KLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKI 176
+ D+N K++ +++ E+T ++ +++ E+ + + + ++T+ K
Sbjct: 1358 QQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVL---EAKLEEVERLATELEKWKE 1414
Query: 177 K--EFNAENDLLKSSLDQLRTEFLKEINDIIDCLRK-----NANETMALQLRTKELSCAL 229
K + +N+ + + T+ L ++ ++ D L++ NA+ L+ + ++ A
Sbjct: 1415 KCNDLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAK 1474
Query: 230 SDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIM---KDRLSRA-EHQ 285
N +N EM+K ++ D R + +N +D+L A E Q
Sbjct: 1475 EAENIRNKEMKK--YAEDRERFFKQQNEMEILTAQLTEKDSDLQKWREERDQLVAALEIQ 1532
Query: 286 LKTNVERVVQLEAALEQAR---SESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDN 342
LK + VQ + +EQ + SE+ +E + + + L+ S + +
Sbjct: 1533 LKALISSNVQKDNEIEQLKRIISETSKIETQIMDIKPKRISSADPDKLQTEPLSTSFEIS 1592
Query: 343 TTHLED 348
+ED
Sbjct: 1593 RNKIED 1598
>AL137068-7|CAD20123.1| 1007|Homo sapiens centrosomal protein 110kDa
protein.
Length = 1007
Score = 51.2 bits (117), Expect = 1e-05
Identities = 67/292 (22%), Positives = 122/292 (41%), Gaps = 23/292 (7%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEE-KKTLQENIDDLRTDLLESELRVKDL 430
AS +S K+M+ E++ NI L++ +K +EE +T+Q+ + D ++ V+ L
Sbjct: 16 ASKRQSEKEME-ELHHNIDDLLQEKKSLECEVEELHRTVQKR--QQQKDFIDGN--VESL 70
Query: 431 VRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEK 490
+ EL+ ++S+ + V E+E + L R++E+ E RLL E E+ K K+
Sbjct: 71 MTELEIEKSLKHHEDIVD-EIECIEKTLLKRRSELREADRLLAEAESELSCTKEKVCLLV 129
Query: 491 AIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNL 550
E + E +NL QLR A +
Sbjct: 130 VWGVSSVWTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQA--DA 187
Query: 551 NDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLN 610
D+ +Q + L E+ K D Q + + E +TE+ L K +K+I+M
Sbjct: 188 KDLEQHKIKQEEILKEINKIVAAKDSDFQC----LSKKKEKLTEE---LQKLQKDIEMAE 240
Query: 611 EKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVL 662
E+ H+ ++ L+ + L K K +T ++M++ +R L
Sbjct: 241 RNEDHHLQVLKESEVLLQAKR-------AELEKLKSQVTSQQQEMAVLDRQL 285
Score = 43.6 bits (98), Expect = 0.002
Identities = 90/506 (17%), Positives = 210/506 (41%), Gaps = 42/506 (8%)
Query: 2 KQEELEIQQN---QTDGCLYEDLNEQES-ITSESHKITKLKTVWQEKMVTFEKSKK--EL 55
K+EEL + Q Q L E L E+ +T + + I ++K++ +E ++F+K + ++
Sbjct: 288 KKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEE--LSFQKGELNVQI 345
Query: 56 EDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKA 115
+R+ Q+ + + ++++ ++++ E +I+++ +L +L L + +
Sbjct: 346 SERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRV 405
Query: 116 LEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMK 175
E L+ + + L + N ++ ++K I W + L+ ++K +
Sbjct: 406 SE---LEKTQVAVLEEKLELEN-----LQQISQQQKGEIEWQKQLLERDK--------RE 449
Query: 176 IKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELS-CALSDLNT 234
I+ AE+ L+S ++ L E +++ + D K +T + +E S S+L
Sbjct: 450 IERMTAESRALQSCVECLSKE-KEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEK 508
Query: 235 QNAEMRKQIHSGD--HHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVER 292
+RK D + + N + +++ L+ + L +
Sbjct: 509 LELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQD 568
Query: 293 VVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFD---QELNKLTQSIKDNTTHLEDI 349
++ + SE L++ + ++ + Q+L L I++N L
Sbjct: 569 LLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQ 628
Query: 350 ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTL 409
+ ++LQ + + ++ E+ +KL ++ K + E +TL
Sbjct: 629 EMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTL 688
Query: 410 QEN---IDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTE-I 465
QE + L L +++ ++ + ++L EK L +QKE +S + D + + +
Sbjct: 689 QEEERWCESLEKTLSQTKRQLSEREQQLVEKSGEL---LALQKEADSMRADFSLLRNQFL 745
Query: 466 EEYKRLLFEKGEEIDELKSKLSTEKA 491
E K+ EK ++ LK L +++
Sbjct: 746 TERKKA--EK--QVASLKEALKIQRS 767
Score = 43.2 bits (97), Expect = 0.003
Identities = 77/465 (16%), Positives = 187/465 (40%), Gaps = 25/465 (5%)
Query: 25 ESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVN 84
E ++ E + + +W++K+ ++ E+ N ME ++L ++ L Q+++
Sbjct: 465 ECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEE--NSKME-QSNLEKLELNVRKLQQELD 521
Query: 85 LPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCE 144
+ ++L + N +QL + E + + + + LL+
Sbjct: 522 QLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLS 581
Query: 145 ETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDI 204
E +K+I W +K TK +++ + E + LK ++ + L++ +
Sbjct: 582 EQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERES 641
Query: 205 IDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXX 264
+ + + T+ Q +L L+D ++ ++ ++ + +
Sbjct: 642 EESKLETSKVTLKEQQH--QLEKELTDQKSKLDQVLSKVLAAEER------------VRT 687
Query: 265 XXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXX 324
++ LS+ + QL +++V+ L + E+ S+
Sbjct: 688 LQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTE 747
Query: 325 XEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHE 384
+ ++++ L +++K + LE L +++ S + ++ + + E
Sbjct: 748 RKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQDNHERARRLMKE 807
Query: 385 MNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRT--DLLESELR--VKDLVRELDE---- 436
+N + E++K+ + + ++ E D +RT ++ E+R +K+L + L E
Sbjct: 808 LNQMQYEYTELKKQMANQKDLERRQMEISDAMRTLKSEVKDEIRTSLKNLNQFLPELPAD 867
Query: 437 KESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE 481
E+ILE + ++ ELES K +L E ++L F + +DE
Sbjct: 868 LEAILERNENLEGELESLKENLPFTMNEGPFEEKLNFSQVHIMDE 912
Score = 35.1 bits (77), Expect = 0.86
Identities = 24/88 (27%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
Query: 404 EEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKT 463
++K+ L E + L+ D+ +E ++ L E E +L+ K+ ELE K+ + ++
Sbjct: 220 KKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRA---ELEKLKSQVTSQQQ 276
Query: 464 EIEEYKRLLFEKGEEIDELKSKLSTEKA 491
E+ R L K EE+ L+ + KA
Sbjct: 277 EMAVLDRQLGHKKEELHLLQGSMVQAKA 304
Score = 31.9 bits (69), Expect = 8.0
Identities = 71/372 (19%), Positives = 143/372 (38%), Gaps = 23/372 (6%)
Query: 275 MKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNK 334
+++ L E ++ + ++++ LE+ + L + ++ ++E
Sbjct: 306 LQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEEN 365
Query: 335 LTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH--EMNLNIAKL 392
L ++ + H ++ + LQ ++ K E L + L
Sbjct: 366 LQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENL 425
Query: 393 IEIEKKYNDSIEEKKTLQENIDDLRTDLLESELR-VKDLVRELD-EKESILETKQCVQKE 450
+I ++ IE +K L E D + + +E R ++ V L EKE + E +K+
Sbjct: 426 QQISQQQKGEIEWQKQLLER-DKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKK 484
Query: 451 LESTKTDL----EHRKTEIEEYKRL---LFEKGEEIDEL-KSKLSTEKAIKDIXXXXXXX 502
L TK L E+ K E ++L + + +E+D+L + KLS DI
Sbjct: 485 LAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHN---DISAMQQQL 541
Query: 503 XXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRD 562
++ + + L K+Q L E D+ N+ D
Sbjct: 542 QEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQK--DISEWANRFED 599
Query: 563 -KLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM----LNEKEEEHM 617
+ E TK+Q+ + + +EN++K + + M Q ++ +E K+ + KE++H
Sbjct: 600 CQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQ 659
Query: 618 NIINLLHNKLEL 629
L K +L
Sbjct: 660 LEKELTDQKSKL 671
>AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein.
Length = 1870
Score = 51.2 bits (117), Expect = 1e-05
Identities = 136/696 (19%), Positives = 272/696 (39%), Gaps = 50/696 (7%)
Query: 23 EQESITSESHKITKLKTVWQEKMVTF-----EKSKKELEDRQNQVMELYASLRNTHRKMK 77
EQE+ E KT+ K +TF EK +L++ ++ SL+ KM
Sbjct: 662 EQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMA 721
Query: 78 LLGQKVNLPSAEELHI---MNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLN 134
L + +E+ + + + K S ++ +L + +E+ L + K+
Sbjct: 722 QLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQ 781
Query: 135 IPNSLVD-KCE-ETLFKRKEIINW----FESLMSQEKGISTKT--LTMKIKEFNAENDLL 186
+ + L D + E +TL K E + E L + K + +T L K+ EN L
Sbjct: 782 LESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRL 841
Query: 187 KSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCA-LSDLNTQNAEMRKQ--- 242
+ + ++ L+E N I L K N+T++ ++ + SC L +L +N E+ K+
Sbjct: 842 RQQAE-IKDTTLEENNVKIGNLEKE-NKTLSKEIGIYKESCVRLKELEKENKELVKRATI 899
Query: 243 -IHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAE--HQLKTNVERVVQLEAA 299
I + R + K L++ H ++ +R LE+
Sbjct: 900 DIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESK 959
Query: 300 LEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSX 359
LE +S ++ +++Q+L + +++K N L+ +QS
Sbjct: 960 LESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS 1019
Query: 360 XXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTD 419
+ + ++ E+ +LIE+E+ EK+ L+ + L T
Sbjct: 1020 PPISGEDN-----KWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQ 1074
Query: 420 LLESELRVKDLVRE---LDEKESILETK----QCVQKELESTKTDLEHRKTEIEEYKRLL 472
+ ++ L R+ L E+ + L+T+ Q L S T L ++ ++ + L
Sbjct: 1075 NNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSL 1134
Query: 473 FEKGEEIDELKSKLST--EKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEE 530
+ E + + + L + + IKD +S K+ E
Sbjct: 1135 ENENESVIKEREDLKSLYDSLIKD-HEKLELLHERQASEYESLISKHGTLKSAHKNLEVE 1193
Query: 531 LMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQE----EYDEKLQTKENEIK 586
+L+++ QL + L D+ M+ +++K+ K E EY +KL + + +
Sbjct: 1194 HRDLEDRYNQLLK--QKGQLEDLEKMLKVEQEKMLLENKNHETVAAEY-KKLCGENDRLN 1250
Query: 587 RLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIIT-LAKYK 645
+ ++ VL K +K L + + +KL+ + + +D+ T L
Sbjct: 1251 HTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQ-QLDITSTKLNNQC 1309
Query: 646 KSLTLVLEKMSISNRVLKCSLLGVVTQSRT-LRKNM 680
+ L+ + + NR L + ++ Q+RT L +NM
Sbjct: 1310 ELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNM 1345
Score = 43.6 bits (98), Expect = 0.002
Identities = 90/480 (18%), Positives = 191/480 (39%), Gaps = 25/480 (5%)
Query: 187 KSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSG 246
K+ + +LR E ++ ++DC K E M ++L K L +L + R
Sbjct: 257 KAKIRRLRQELEEKTEQLLDC--KQELEQMEIEL--KRLQQENMNLLSDARSARMYRDEL 312
Query: 247 DHHRPYANR-NXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARS 305
D R A R + K R+ + + +E LE LE R+
Sbjct: 313 DALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRA 372
Query: 306 ES---WSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXX 362
S LE+ + D + K+ + +++N T LE +A + +S
Sbjct: 373 RSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMT-LE-MAQKQSMDESLHLG 430
Query: 363 XXXXXXXXSASYNKS-IKDMKHEMN-LNIAKLIEIE---KKYNDSIEEKKTLQENIDDLR 417
++ +++ K + HE+N L ++L+++E + ++EE +T ++++
Sbjct: 431 WELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNA 490
Query: 418 TDLLESELRVKDLVRELDEKES-ILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKG 476
+ +L+ E + L ++++ E+ I++ KQ +Q ++ DL K ++E+ L E
Sbjct: 491 SKILKMEKENQRLSKKVEILENEIVQEKQSLQ-NCQNLSKDLMKEKAQLEKTIETLRENS 549
Query: 477 EEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKN 536
E ++ + E + + +K +L ++
Sbjct: 550 ERQIKILEQ-ENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEF 608
Query: 537 QITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQE 596
+ Q+++ ++ + G + ++L L E+ +E LQ K +K E + E
Sbjct: 609 EKRQIKK--ELEHYKEKGERAEELENELHHL----EKENELLQKKITNLKITCEKIEALE 662
Query: 597 HVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMS 656
++ E+E + L + + N+ L + LE N + + L + +SL KM+
Sbjct: 663 QENSELERENRKLKKTLDSFKNLTFQLES-LEKENSQLDEENLELRRNVESLKCASMKMA 721
Score = 40.7 bits (91), Expect = 0.017
Identities = 121/661 (18%), Positives = 260/661 (39%), Gaps = 65/661 (9%)
Query: 1 MKQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQN 60
M +++LE + ++D L+E E + ++ H + + + ++K+ + LE Q
Sbjct: 362 MLEDQLEGTRARSDK-LHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQK 420
Query: 61 QVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEP--KALEH 118
Q M+ L ++ + P H +N +L+ +LL+L + K +E
Sbjct: 421 QSMDESLHLGWELEQISRTSELSEAPQKSLGHEVN--ELTSSRLLKLEMENQSLTKTVEE 478
Query: 119 --STLDNKVTFDVNKLLNIP------NSLVDKCEETLFKRKEII----NWFESLMSQ--- 163
+T+D+ V + +K+L + + V+ E + + K+ + N + LM +
Sbjct: 479 LRTTVDS-VEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQ 537
Query: 164 -EKGIST--KTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQL 220
EK I T + +IK EN+ L ++ LR + + K E L
Sbjct: 538 LEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEK---ENKILHE 594
Query: 221 RTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLS 280
KE S LS + + +++K++ +H++ R +++ +++
Sbjct: 595 SIKETSSKLSKIEFEKRQIKKEL---EHYKEKGER--AEELENELHHLEKENELLQKKIT 649
Query: 281 RAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXX---------XXXEDFDQE 331
LK E++ LE + E+ L++T+ ++ + E
Sbjct: 650 N----LKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLE 705
Query: 332 LNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKS-----------IKD 380
L + +S+K + + + L ++L+S AS+ K+ I++
Sbjct: 706 LRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIEN 765
Query: 381 MKHEMNLNIA--KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKE 438
+ + L + K+ ++E + D E +TLQ+N+++L+ E K+ + L+++
Sbjct: 766 QRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKE-NKSLEQET 824
Query: 439 SILE-TKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEK----AIK 493
S LE K+ ++KE + + E + T +EE + +E L ++ K +K
Sbjct: 825 SQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLK 884
Query: 494 DIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDV 553
++ S+ + +L+ +L + G
Sbjct: 885 ELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLH 944
Query: 554 GNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKE 613
R KL E +K + + L+ KE +I L + E + + +E+K + +
Sbjct: 945 DEQSTDDRYKLLE-SKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNY 1003
Query: 614 E 614
E
Sbjct: 1004 E 1004
Score = 39.9 bits (89), Expect = 0.030
Identities = 62/296 (20%), Positives = 127/296 (42%), Gaps = 19/296 (6%)
Query: 375 NKSIKDMKHEMNLNIAKLIEIEKKYNDSIE-EKKTLQENIDDLRT-DLLESELRVKDLVR 432
+K + K ++ I L E ++ +E E + L + + LR + +E RVKD+ +
Sbjct: 528 SKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEK 587
Query: 433 ELDE-KESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
E ESI ET + K +E K + K E+E YK EKGE +EL+++L +
Sbjct: 588 ENKILHESIKETSSKLSK-IEFEKRQI---KKELEHYK----EKGERAEELENELHHLEK 639
Query: 492 IKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLN 551
++ E + + + L + KN QL ++
Sbjct: 640 ENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQL 699
Query: 552 DVGNM---INQQRDKLFELTKRQEEYDEK-LQTKENEIKRLVESMTEQEHVLNKKEKEIK 607
D N+ N + K + Q + + K L++++ ++K+ +E + + E +
Sbjct: 700 DEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQ 759
Query: 608 MLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVLK 663
L+ + + + + K++ + E+++ L ++L LE++ IS++ L+
Sbjct: 760 GLDIENQRLQKTLENSNKKIQ-QLESELQ---DLEMENQTLQKNLEELKISSKRLE 811
>AB037819-1|BAA92636.2| 1586|Homo sapiens KIAA1398 protein protein.
Length = 1586
Score = 51.2 bits (117), Expect = 1e-05
Identities = 44/221 (19%), Positives = 98/221 (44%), Gaps = 13/221 (5%)
Query: 278 RLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQ 337
RL E Q+ + ++L A+EQ + ++ L + ++L+ LTQ
Sbjct: 1164 RLKELESQVSGLEKEAIELREAVEQQKVKNNDLREKNWKAMEALATAEQACKEKLHSLTQ 1223
Query: 338 SIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAK------ 391
+ +++ L + + +++ +Y + ++D+K E + K
Sbjct: 1224 AKEESEKQL--CLIEAQTMEALLALLPELSVLAQQNYTEWLQDLK-EKGPTLLKHPPAPA 1280
Query: 392 --LIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETK-QCVQ 448
++ K ++ E + TLQ D R+ L E+E ++DL + ++E+E + K +
Sbjct: 1281 EPSSDLASKLREAEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEEQVWRAKVGAAE 1340
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
+EL+ ++ ++H + +E+ K L E +++ E L E
Sbjct: 1341 EELQKSRVTVKHLEEIVEKLKGEL-ESSDQVREHTLHLEAE 1380
>M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy chain
protein.
Length = 1937
Score = 50.8 bits (116), Expect = 2e-05
Identities = 84/463 (18%), Positives = 177/463 (38%), Gaps = 26/463 (5%)
Query: 164 EKGIST-KTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRT 222
EK ++T K K K+ A+++ + L++ LKE ND+ ++ A+ + R
Sbjct: 849 EKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERC 908
Query: 223 KELSCALSDLN------TQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMK 276
++L L T+ AE ++I++ + + + ++
Sbjct: 909 EQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 968
Query: 277 DRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLT 336
+ E+++K E + L+ + + E +L+ T ED L K
Sbjct: 969 KQKHATENKVKNLTEEMAGLDETIAKLSKEKKALQET-HQQTLDDLQAEEDKVNILTKAK 1027
Query: 337 QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIE 396
++ LE +KL+ +S DM+++ +++
Sbjct: 1028 TKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQ-------QLD 1080
Query: 397 KKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKT 456
+K E L I+D + ++ + ++K+L ++E +E ++ + + E ++
Sbjct: 1081 EKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRS 1140
Query: 457 DLEHRKTEIEEYKRLLFEKGEEID---ELKSKLSTE--KAIKDIXXXXXXXXXXXXXXXX 511
DL E+EE L E G EL K E K +D+
Sbjct: 1141 DLSR---ELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRK 1197
Query: 512 XXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQ 571
Q+ + L+ + ++L+ D+L+ I++ + L ++ +
Sbjct: 1198 KHADSMAELGEQIDNLQRVKQKLEKEKSELKM--ETDDLSSNAEAISKAKGHLEKMCRSL 1255
Query: 572 EEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEI-KMLNEKE 613
E+ L+TKE E +RL+ +T Q L + E + L+E++
Sbjct: 1256 EDQVSGLKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEQD 1298
Score = 49.2 bits (112), Expect = 5e-05
Identities = 68/380 (17%), Positives = 159/380 (41%), Gaps = 24/380 (6%)
Query: 277 DRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLT 336
++L + + QL+ ++ V + E+ +E + +R + +D + L K+
Sbjct: 909 EQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 968
Query: 337 QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHE---MNLNIAKLI 393
+ ++++ L ++ +++ D++ E +N+
Sbjct: 969 KQKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKT 1028
Query: 394 EIEKKYND---SIEEKKTLQENID----DLRTDLL---ESELRVKDLVRELDEK--ESIL 441
++E++ +D S+E++K L+ +++ L DL ES + +++ ++LDEK +
Sbjct: 1029 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEF 1088
Query: 442 ETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEID-ELKSKLSTEKAIKDIXXXXX 500
E + K + +++ +K +I+E + + E GEEI+ E S+ EK D+
Sbjct: 1089 EISNLISKIEDEQAVEIQLQK-KIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELE 1147
Query: 501 XXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNM--IN 558
+ + + + +L+ Q A +M +
Sbjct: 1148 EISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELG 1207
Query: 559 QQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKK----EKEIKMLNEKEE 614
+Q D L + ++ E+ +L+ + +++ E++++ + L K E ++ L KEE
Sbjct: 1208 EQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGHLEKMCRSLEDQVSGLKTKEE 1267
Query: 615 EHMNIIN-LLHNKLELRNEA 633
E +IN L + L+ EA
Sbjct: 1268 EQQRLINDLTAQRARLQTEA 1287
Score = 46.0 bits (104), Expect = 5e-04
Identities = 58/285 (20%), Positives = 127/285 (44%), Gaps = 30/285 (10%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLV 431
A+ + + K E+ + AK E+E+K ++EK LQ + L ++E R + L+
Sbjct: 853 ATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLI 912
Query: 432 RELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
+ + E+ ++ +E E +L +K ++E+ E ++ID+L+ L+ +
Sbjct: 913 KNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDE---CSELKKDIDDLELTLAKVEK 969
Query: 492 IKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQL-REFGAFDNL 550
K E+++K+ EE+ L I +L +E A
Sbjct: 970 QK------------------------HATENKVKNLTEEMAGLDETIAKLSKEKKALQET 1005
Query: 551 N-DVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKML 609
+ + + + DK+ LTK + + ++++ E +++ + + E K E ++K+
Sbjct: 1006 HQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLA 1065
Query: 610 NEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEK 654
E + N L KLE + E +I +I+ + ++++ + L+K
Sbjct: 1066 QESTMDMENDKQQLDEKLE-KKEFEISNLISKIEDEQAVEIQLQK 1109
Score = 46.0 bits (104), Expect = 5e-04
Identities = 105/593 (17%), Positives = 215/593 (36%), Gaps = 28/593 (4%)
Query: 21 LNEQESITSESHK-ITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLL 79
+ +Q+ T K +T+ E + K KK L++ Q ++ L+ K+ +L
Sbjct: 967 VEKQKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLD---DLQAEEDKVNIL 1023
Query: 80 GQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHST-LDNKVTFDVNKLLNIPNS 138
K +++ + L E+ L++ + LE L + T D+ N
Sbjct: 1024 -TKAKTKLEQQVDDLE-GSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDME---NDKQQ 1078
Query: 139 LVDKCEETLFKRKEIINWFESLMSQEKGISTKT--LTMKIKEFNAENDLLKSS---LDQL 193
L +K E+ F+ +I+ E + E + K L +I+E E + ++S ++
Sbjct: 1079 LDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQ 1138
Query: 194 RTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYA 253
R++ +E+ +I + L + T A K+ L E Q H A
Sbjct: 1139 RSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQ-HEA---MVAA 1194
Query: 254 NRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERT 313
R +K +L + + +LK + + A+ +A+ + R+
Sbjct: 1195 LRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGHLEKMCRS 1254
Query: 314 VXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSAS 373
+ E+ + +N LT T + + +L AS
Sbjct: 1255 LEDQVSGLKTKEEEQQRLINDLTAQRARLQTEAGEYS---RQLDEQDALVSQLSRSKQAS 1311
Query: 374 YNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRE 433
+ I+++KH++ + S + L+E ++ + E + + E
Sbjct: 1312 -TQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSE 1370
Query: 434 LDEKESILETKQCVQ-KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAI 492
+ + + ET + +ELE K L R E EE+ + K +++ K +L E +
Sbjct: 1371 VAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNE--V 1428
Query: 493 KDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLND 552
+D+ S+ K YEE + + +Q L
Sbjct: 1429 EDLMLDVERSNAACAALDKKQRNFDKVL-SEWKQKYEE-TQAELEASQKESRSLSTELFK 1486
Query: 553 VGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKE 605
V N+ + D+L L + + +++ +I + + E E + + E+E
Sbjct: 1487 VKNVYEESLDQLETLRRAHKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQE 1539
Score = 42.7 bits (96), Expect = 0.004
Identities = 44/241 (18%), Positives = 98/241 (40%), Gaps = 6/241 (2%)
Query: 391 KLIEIEKKYNDSIEEKKTLQ---ENIDDLRTDLLESELRVKDLVRELDEKESILETKQC- 446
+L +++ Y +S+++ +TL+ +N+ +DL E + EL++ + +E ++C
Sbjct: 1483 ELFKVKNVYEESLDQLETLRRAHKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCE 1542
Query: 447 VQKELESTKTDLEHRKTEIEEYKRLLFEKGEEID-ELKSKLSTEKAIKDIXXXXXXXXXX 505
+Q LE + LEH + +I + L + E+D ++ K +K
Sbjct: 1543 IQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQS 1602
Query: 506 XXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLF 565
+ +M+ E+ N +L + N + ++ + + L
Sbjct: 1603 TLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAA-ESLRNYRNTQGILKETQLHLD 1661
Query: 566 ELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHN 625
+ + QE+ E+L E L + E L + E+ K+ ++ + + LLH
Sbjct: 1662 DALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHT 1721
Query: 626 K 626
+
Sbjct: 1722 Q 1722
Score = 35.1 bits (77), Expect = 0.86
Identities = 40/211 (18%), Positives = 87/211 (41%), Gaps = 11/211 (5%)
Query: 285 QLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTT 344
Q + E +L+ AL +A SE + + E+ ++ KL Q +++
Sbjct: 1349 QYEEEQEGKAELQRALSKANSE---VAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 1405
Query: 345 HLEDI---ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYND 401
H+E + + EK + N + + + L E ++KY +
Sbjct: 1406 HVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEE 1465
Query: 402 SIEEKKTLQENIDDLRTDLLESELRVKDLVRE-LDEKESILETKQCVQKELESTKTDLEH 460
+ E + Q+ L T+L +VK++ E LD+ E++ + +Q+E+ +
Sbjct: 1466 TQAELEASQKESRSLSTELF----KVKNVYEESLDQLETLRRAHKNLQQEISDLTEQIAE 1521
Query: 461 RKTEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
+I E +++ + +E E+++ L +A
Sbjct: 1522 GGKQIHELEKIKKQVEQEKCEIQAALEEAEA 1552
>AY237537-1|AAP04414.1| 1335|Homo sapiens KIF27B protein.
Length = 1335
Score = 50.8 bits (116), Expect = 2e-05
Identities = 54/253 (21%), Positives = 112/253 (44%), Gaps = 19/253 (7%)
Query: 381 MKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESI 440
++ LN+ KL E+ ++ ++ + L NI ++ DL +K+L++ ++ +S+
Sbjct: 701 LQESQELNLQKLKNSERILTEAKQKMRELTINIK-MKEDL------IKELIKTGNDAKSV 753
Query: 441 LETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXX 500
+ Q L+ TK LEH + E+ K L E +++ EL++K ++ A+K
Sbjct: 754 SK-----QYSLKVTK--LEH---DAEQAKVELIETQKQLQELENKDLSDVAMKVKLQKEF 803
Query: 501 XXXXXXXXXXXXXXXXXXXRESQMKSYYEEL--MNLKNQITQLREFGAFDNLNDVGNMIN 558
+E +K E+L NLK + L++ ++
Sbjct: 804 RKKMDAAKLRVQEIQLKTGQEEGLKPKAEDLDACNLKRRKGSFGSIDHLQKLDEQKKWLD 863
Query: 559 QQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMN 618
++ +K+ + EE + L+ +E + + + E+ H+ NKK + + LN +
Sbjct: 864 EEVEKVLNQRQELEELEADLKKREAIVSKKEALLQEKSHLENKKLRSSQALNTDSLKIST 923
Query: 619 IINLLHNKLELRN 631
+NLL +L +N
Sbjct: 924 RLNLLEQELSEKN 936
Score = 37.1 bits (82), Expect = 0.21
Identities = 63/262 (24%), Positives = 123/262 (46%), Gaps = 30/262 (11%)
Query: 2 KQEELEIQQNQTDGCLYEDL---NEQESITSE-SHKITKLKTVWQEKMVTFEKSKKELED 57
K EL I + + E + N+ +S++ + S K+TKL+ ++ V +++K+L++
Sbjct: 725 KMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQE 784
Query: 58 RQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKA-- 115
+N+ L + K+KL + A +L + + + ++ G +PKA
Sbjct: 785 LENK------DLSDVAMKVKLQKEFRKKMDAAKLRVQEIQLKTGQE-----EGLKPKAED 833
Query: 116 LEHSTLD-NKVTF----DVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTK 170
L+ L K +F + KL L ++ E+ L +R+E+ L +E +S K
Sbjct: 834 LDACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKK 893
Query: 171 TLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANE-TMALQLRTKELSCAL 229
++ K + EN L+SS L T+ LK I+ ++ L + +E + LQ T E +
Sbjct: 894 EALLQEKS-HLENKKLRSS-QALNTDSLK-ISTRLNLLEQELSEKNVQLQTSTAEEKTKI 950
Query: 230 SD----LNTQNAEMRKQIHSGD 247
S+ L + +++K+ H+ D
Sbjct: 951 SEQVEVLQKEKDQLQKRRHNVD 972
Score = 33.1 bits (72), Expect = 3.5
Identities = 53/266 (19%), Positives = 115/266 (43%), Gaps = 30/266 (11%)
Query: 371 SASYNKSIKDMKHEMNLNIAKLIEIEKKY----NDSIEEKKTLQENIDDLRTDLLESELR 426
S Y+ + ++H+ +LIE +K+ N + + + + R + ++LR
Sbjct: 754 SKQYSLKVTKLEHDAEQAKVELIETQKQLQELENKDLSDVAMKVKLQKEFRKKMDAAKLR 813
Query: 427 VKDLVRELDEKESILETKQ----CVQKELESTKTDLEHRKTEIEEYKRLLFEKGE----- 477
V+++ + ++E + + C K + + ++H + +++E K+ L E+ E
Sbjct: 814 VQEIQLKTGQEEGLKPKAEDLDACNLKRRKGSFGSIDHLQ-KLDEQKKWLDEEVEKVLNQ 872
Query: 478 --EIDELKSKLSTEKAI---KDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELM 532
E++EL++ L +AI K+ + S + E+ +
Sbjct: 873 RQELEELEADLKKREAIVSKKEALLQEKSHLENKKLRSSQALNTDSLKISTRLNLLEQEL 932
Query: 533 NLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESM 592
+ KN Q +++ ++ +++D +L KR+ DEKL+ R++
Sbjct: 933 SEKNVQLQTSTAEEKTKISEQVEVLQKEKD---QLQKRRHNVDEKLKNG-----RVLSP- 983
Query: 593 TEQEHVLNKKEKEIKMLNEKEEEHMN 618
E+EHVL + E+ I+ L E E+ N
Sbjct: 984 -EEEHVLFQLEEGIEAL-EAAIEYRN 1007
>Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9,
non-muscle protein.
Length = 1960
Score = 50.4 bits (115), Expect = 2e-05
Identities = 119/634 (18%), Positives = 247/634 (38%), Gaps = 64/634 (10%)
Query: 4 EELEIQQNQTDGCLYEDLNEQES-ITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQV 62
EEL + L E ++ E+ + E + L+ ++ ++ +++LE+ ++
Sbjct: 900 EELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESAR 959
Query: 63 MELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLD 122
+L T K+K L ++ + + + KL +++ + + T +
Sbjct: 960 QKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTT--------NLTEE 1011
Query: 123 NKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAE 182
+ + + KL N +++ EE L + ++ E + +G ST L+ +I E A+
Sbjct: 1012 EEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTD-LSDQIAELQAQ 1070
Query: 183 NDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQ 242
LK L + E + + + + A + MAL+ + +L +Q +E+++
Sbjct: 1071 IAELKMQLAKKEEELQAALARVEE---EAAQKNMALK--------KIRELESQISELQED 1119
Query: 243 IHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQ 302
+ S A+RN K L LKT +E + AA ++
Sbjct: 1120 LES-----ERASRNKAEK--------------QKRDLGEELEALKTELEDTLDSTAAQQE 1160
Query: 303 ARSESWSLERTVXXXXXXXXXXXEDFDQELN-KLTQSIKDNTTHLEDIALAREKLQSXXX 361
RS+ + E QE+ K +Q++++ LE + L+
Sbjct: 1161 LRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQ 1220
Query: 362 XXXXXXXXXSASYNKSIK---DMKHEMNLNIAKLIEIEKKYNDS------IEEKKT-LQE 411
+ ++ D +H+ A+L E++ K+N+ + +K T LQ
Sbjct: 1221 TLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQV 1280
Query: 412 NIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRL 471
+D++ L +S+ + L ++ ES L+ Q + +E K L + ++E+ K
Sbjct: 1281 ELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNS 1340
Query: 472 LFEKGEEIDELKSKLSTEKA-----IKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKS 526
E+ EE +E K L + A + D+ E +
Sbjct: 1341 FREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQR 1400
Query: 527 YYEELM---NLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKEN 583
+ E++ L+ T+L++ L+D+ ++ QR L K+Q+++D+ L ++
Sbjct: 1401 HEEKVAAYDKLEKTKTRLQQ-----ELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKT 1455
Query: 584 EIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHM 617
+ E E +KE + L EE M
Sbjct: 1456 ISAKYAEERDRAEAEAREKETKALSLARALEEAM 1489
Score = 48.0 bits (109), Expect = 1e-04
Identities = 56/283 (19%), Positives = 121/283 (42%), Gaps = 15/283 (5%)
Query: 382 KHE-MNLNIAKLIEIEKKYNDSIEE-KKTLQENIDDLRTDLLESELRVKDLVRELDEKES 439
KHE M ++ + + E+K +E+ ++ L+ + DL + E + ++ +L +L +KE
Sbjct: 1024 KHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEE 1083
Query: 440 ILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEID-ELKSKLSTEKAIKDIXXX 498
L+ + E E+ + ++ +K I E + + E E+++ E S+ EK +D+
Sbjct: 1084 ELQAA-LARVEEEAAQKNMALKK--IRELESQISELQEDLESERASRNKAEKQKRDLGEE 1140
Query: 499 XXXXXXXXXXXXXXXXXXXXXRESQ-------MKSYYEELMNLKNQITQLREFGAFDNLN 551
R + K+ EE + QI ++R+ + +
Sbjct: 1141 LEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHS-QAVE 1199
Query: 552 DVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNE 611
++ + Q + L K ++ + + NE+K L++ + EH K E +++ L
Sbjct: 1200 ELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQV 1259
Query: 612 KEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEK 654
K E + L +K+ + + ++D + L S + L K
Sbjct: 1260 KFNEGERVRTELADKV-TKLQVELDNVTGLLSQSDSKSSKLTK 1301
Score = 45.6 bits (103), Expect = 6e-04
Identities = 116/646 (17%), Positives = 256/646 (39%), Gaps = 77/646 (11%)
Query: 6 LEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMEL 65
LE Q T L E+ ++ S++++ ++ K ++E++ E++K LE Q+ L
Sbjct: 1306 LESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLE---KQIATL 1362
Query: 66 YASLRNTHRKMKLLGQKVN-LPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNK 124
+A + + +KM+ V L +AEE V + + L L E K + L+
Sbjct: 1363 HAQVADMKKKME---DSVGCLETAEE-----VKRKLQKDLEGLSQRHEEKVAAYDKLEKT 1414
Query: 125 VTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAEND 184
T +L ++ L D ++ ++ F+ L+++EK IS K + E D
Sbjct: 1415 KTRLQQELDDLLVDL-DHQRQSACNLEKKQKKFDQLLAEEKTISAK--------YAEERD 1465
Query: 185 LLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIH 244
++ + T+ L + + + + A L+ K+ + DL + ++ K +H
Sbjct: 1466 RAEAEAREKETKALSLARALEEAMEQKAE----LERLNKQFRTEMEDLMSSKDDVGKSVH 1521
Query: 245 SGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQAR 304
+ + + MK +L E +L+ + ++LE L+ +
Sbjct: 1522 ELEKSKRALEQQVEE---------------MKTQLEELEDELQATEDAKLRLEVNLQAMK 1566
Query: 305 SESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXX 364
++ ER + + +++ ++ ++D AR+KL+
Sbjct: 1567 AQ---FERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLE 1623
Query: 365 XXXXXXSASYNKSIKDMK----------HEMNLNIAKLIEIEKKYNDSIEEKKTLQENID 414
+ + +++IK ++ E++ A EI + ++ ++ K+++ +
Sbjct: 1624 AHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMI 1683
Query: 415 DLRTDLLESELRVKDLVRELDE----------KESI-LETKQCVQKELESTKTDLEHRKT 463
L+ +L +E + +E DE K ++ LE K+ ++ + + +LE +
Sbjct: 1684 QLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQG 1743
Query: 464 EIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQ 523
E L + +ID++ + L+ E++ E
Sbjct: 1744 NTELINDRLKKANLQIDQINTDLNLERS---HAQKNENARQQLERQNKELKVKLQEMEGT 1800
Query: 524 MKSYYE-ELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKE 582
+KS Y+ + L+ +I QL E DN ++R + +R E+ + + +
Sbjct: 1801 VKSKYKASITALEAKIAQLEE--QLDN-------ETKERQAACKQVRRTEKKLKDVLLQV 1851
Query: 583 NEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
++ +R E +Q + + K++K E+ EE N KL+
Sbjct: 1852 DDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQ 1897
Score = 44.0 bits (99), Expect = 0.002
Identities = 70/384 (18%), Positives = 151/384 (39%), Gaps = 47/384 (12%)
Query: 274 IMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXE---DFDQ 330
+M ++L E QL+ E + E + ++ LE E
Sbjct: 878 LMAEKLQLQE-QLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQA 936
Query: 331 ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIA 390
E K+ Q+I++ LE+ AR+KLQ + +K ++ E
Sbjct: 937 EKKKMQQNIQELEEQLEEEESARQKLQ-----------LEKVTTEAKLKKLEEEQ----- 980
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKE 450
I +E + +EKK L++ I + T+L E E + K L + ++ E+++
Sbjct: 981 --IILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMI--------- 1029
Query: 451 LESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXX 510
TDLE R EE +R +E+++ + KL + D+
Sbjct: 1030 -----TDLEERLRR-EEKQR------QELEKTRRKLEGDST--DLSDQIAELQAQIAELK 1075
Query: 511 XXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKR 570
++ + EE + ++RE + ++++ + +R + K+
Sbjct: 1076 MQLAKKEEELQAALARVEEEAAQKNMALKKIRELES--QISELQEDLESERASRNKAEKQ 1133
Query: 571 QEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELR 630
+ + E+L+ + E++ ++S Q+ + +K+E+E+ +L + EE ++ +
Sbjct: 1134 KRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQK 1193
Query: 631 NEADIDVIITLAKYKKSLTLVLEK 654
+ ++ + + K + LEK
Sbjct: 1194 HSQAVEELAEQLEQTKRVKANLEK 1217
Score = 37.1 bits (82), Expect = 0.21
Identities = 61/337 (18%), Positives = 127/337 (37%), Gaps = 8/337 (2%)
Query: 158 ESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMA 217
E + +E+ + + + + E + L+S L + + +++ + +
Sbjct: 846 EMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRAR 905
Query: 218 LQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKD 277
L + +EL DL + E ++ + +N + +
Sbjct: 906 LTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLE 965
Query: 278 RLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQ 337
+++ E +LK E + LE + E LE + E+ + L KL
Sbjct: 966 KVT-TEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEE-EEKSKSLAKLKN 1023
Query: 338 SIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH---EMNLNIAKLIE 394
+ T LE+ EK + S + I +++ E+ + +AK E
Sbjct: 1024 KHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEE 1083
Query: 395 IEKKYNDSIEEKKTLQENIDDLRTDLLESELRV--KDLVRELDEKESILETKQCVQKELE 452
+ +EE+ Q+N+ + LES++ +DL E + + K+ + +ELE
Sbjct: 1084 ELQAALARVEEEAA-QKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELE 1142
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
+ KT+LE + L ++ +E++ LK L E
Sbjct: 1143 ALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEE 1179
Score = 34.3 bits (75), Expect = 1.5
Identities = 50/317 (15%), Positives = 118/317 (37%), Gaps = 22/317 (6%)
Query: 170 KTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMA----LQLRTKEL 225
K L M +K+ A D + D+ + K + DC+R+ ++T A + + KE
Sbjct: 1613 KKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRE-LDDTRASREEILAQAKEN 1671
Query: 226 SCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKD------RL 279
L + + ++++++ + + + A + +++ R+
Sbjct: 1672 EKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARI 1731
Query: 280 SRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSI 339
++ E +L+ + L++A + + T E+ Q+L + + +
Sbjct: 1732 AQLEEELEEEQGNTELINDRLKKANLQIDQIN-TDLNLERSHAQKNENARQQLERQNKEL 1790
Query: 340 KDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKY 399
K +E ++ K A + + + E ++ EKK
Sbjct: 1791 KVKLQEMEGTVKSKYK------ASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKL 1844
Query: 400 NDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILE----TKQCVQKELESTK 455
D + + + N + + ++ R+K L R+L+E E + +++ +Q+ELE
Sbjct: 1845 KDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDAT 1904
Query: 456 TDLEHRKTEIEEYKRLL 472
+ E+ K L
Sbjct: 1905 ETADAMNREVSSLKNKL 1921
Score = 33.9 bits (74), Expect = 2.0
Identities = 50/248 (20%), Positives = 97/248 (39%), Gaps = 8/248 (3%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLL--ESELRVKDLVRELDEKESILETKQCVQ 448
+L E+E + + EK LQE + T+L ELR + L + E E I +
Sbjct: 867 RLTEMETLQSQLMAEKLQLQEQL-QAETELCAEAEELRAR-LTAKKQELEEICHDLEARV 924
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXX 508
+E E L+ K ++++ + L E+ EE + + KL EK +
Sbjct: 925 EEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILE 984
Query: 509 XXX-XXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDN--LNDVGNMINQQRDKLF 565
E ++ + L + + L + + D+ + ++ +
Sbjct: 985 DQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQ 1044
Query: 566 ELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHN 625
EL K + + + ++I L + E + L KKE+E++ + EE N+
Sbjct: 1045 ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALK 1104
Query: 626 KL-ELRNE 632
K+ EL ++
Sbjct: 1105 KIRELESQ 1112
>CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein.
Length = 1960
Score = 50.4 bits (115), Expect = 2e-05
Identities = 119/634 (18%), Positives = 247/634 (38%), Gaps = 64/634 (10%)
Query: 4 EELEIQQNQTDGCLYEDLNEQES-ITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQV 62
EEL + L E ++ E+ + E + L+ ++ ++ +++LE+ ++
Sbjct: 900 EELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESAR 959
Query: 63 MELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLD 122
+L T K+K L ++ + + + KL +++ + + T +
Sbjct: 960 QKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTT--------NLTEE 1011
Query: 123 NKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAE 182
+ + + KL N +++ EE L + ++ E + +G ST L+ +I E A+
Sbjct: 1012 EEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTD-LSDQIAELQAQ 1070
Query: 183 NDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQ 242
LK L + E + + + + A + MAL+ + +L +Q +E+++
Sbjct: 1071 IAELKMQLAKKEEELQAALARVEE---EAAQKNMALK--------KIRELESQISELQED 1119
Query: 243 IHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQ 302
+ S A+RN K L LKT +E + AA ++
Sbjct: 1120 LES-----ERASRNKAEK--------------QKRDLGEELEALKTELEDTLDSTAAQQE 1160
Query: 303 ARSESWSLERTVXXXXXXXXXXXEDFDQELN-KLTQSIKDNTTHLEDIALAREKLQSXXX 361
RS+ + E QE+ K +Q++++ LE + L+
Sbjct: 1161 LRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQ 1220
Query: 362 XXXXXXXXXSASYNKSIK---DMKHEMNLNIAKLIEIEKKYNDS------IEEKKT-LQE 411
+ ++ D +H+ A+L E++ K+N+ + +K T LQ
Sbjct: 1221 TLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQV 1280
Query: 412 NIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRL 471
+D++ L +S+ + L ++ ES L+ Q + +E K L + ++E+ K
Sbjct: 1281 ELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNS 1340
Query: 472 LFEKGEEIDELKSKLSTEKA-----IKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKS 526
E+ EE +E K L + A + D+ E +
Sbjct: 1341 FREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQR 1400
Query: 527 YYEELM---NLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKEN 583
+ E++ L+ T+L++ L+D+ ++ QR L K+Q+++D+ L ++
Sbjct: 1401 HEEKVAAYDKLEKTKTRLQQ-----ELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKT 1455
Query: 584 EIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHM 617
+ E E +KE + L EE M
Sbjct: 1456 ISAKYAEERDRAEAEAREKETKALSLARALEEAM 1489
Score = 48.0 bits (109), Expect = 1e-04
Identities = 56/283 (19%), Positives = 121/283 (42%), Gaps = 15/283 (5%)
Query: 382 KHE-MNLNIAKLIEIEKKYNDSIEE-KKTLQENIDDLRTDLLESELRVKDLVRELDEKES 439
KHE M ++ + + E+K +E+ ++ L+ + DL + E + ++ +L +L +KE
Sbjct: 1024 KHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEE 1083
Query: 440 ILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEID-ELKSKLSTEKAIKDIXXX 498
L+ + E E+ + ++ +K I E + + E E+++ E S+ EK +D+
Sbjct: 1084 ELQAA-LARVEEEAAQKNMALKK--IRELESQISELQEDLESERASRNKAEKQKRDLGEE 1140
Query: 499 XXXXXXXXXXXXXXXXXXXXXRESQ-------MKSYYEELMNLKNQITQLREFGAFDNLN 551
R + K+ EE + QI ++R+ + +
Sbjct: 1141 LEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHS-QAVE 1199
Query: 552 DVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNE 611
++ + Q + L K ++ + + NE+K L++ + EH K E +++ L
Sbjct: 1200 ELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQV 1259
Query: 612 KEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEK 654
K E + L +K+ + + ++D + L S + L K
Sbjct: 1260 KFNEGERVRTELADKV-TKLQVELDNVTGLLSQSDSKSSKLTK 1301
Score = 45.6 bits (103), Expect = 6e-04
Identities = 116/646 (17%), Positives = 256/646 (39%), Gaps = 77/646 (11%)
Query: 6 LEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMEL 65
LE Q T L E+ ++ S++++ ++ K ++E++ E++K LE Q+ L
Sbjct: 1306 LESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLE---KQIATL 1362
Query: 66 YASLRNTHRKMKLLGQKVN-LPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNK 124
+A + + +KM+ V L +AEE V + + L L E K + L+
Sbjct: 1363 HAQVADMKKKME---DSVGCLETAEE-----VKRKLQKDLEGLSQRHEEKVAAYDKLEKT 1414
Query: 125 VTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAEND 184
T +L ++ L D ++ ++ F+ L+++EK IS K + E D
Sbjct: 1415 KTRLQQELDDLLVDL-DHQRQSACNLEKKQKKFDQLLAEEKTISAK--------YAEERD 1465
Query: 185 LLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIH 244
++ + T+ L + + + + A L+ K+ + DL + ++ K +H
Sbjct: 1466 RAEAEAREKETKALSLARALEEAMEQKAE----LERLNKQFRTEMEDLMSSKDDVGKSVH 1521
Query: 245 SGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQAR 304
+ + + MK +L E +L+ + ++LE L+ +
Sbjct: 1522 ELEKSKRALEQQVEE---------------MKTQLEELEDELQATEDAKLRLEVNLQAMK 1566
Query: 305 SESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXX 364
++ ER + + +++ ++ ++D AR+KL+
Sbjct: 1567 AQ---FERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLE 1623
Query: 365 XXXXXXSASYNKSIKDMK----------HEMNLNIAKLIEIEKKYNDSIEEKKTLQENID 414
+ + +++IK ++ E++ A EI + ++ ++ K+++ +
Sbjct: 1624 AHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMI 1683
Query: 415 DLRTDLLESELRVKDLVRELDE----------KESI-LETKQCVQKELESTKTDLEHRKT 463
L+ +L +E + +E DE K ++ LE K+ ++ + + +LE +
Sbjct: 1684 QLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQG 1743
Query: 464 EIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQ 523
E L + +ID++ + L+ E++ E
Sbjct: 1744 NTELINDRLKKANLQIDQINTDLNLERS---HAQKNENARQQLERQNKELKVKLQEMEGT 1800
Query: 524 MKSYYE-ELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKE 582
+KS Y+ + L+ +I QL E DN ++R + +R E+ + + +
Sbjct: 1801 VKSKYKASITALEAKIAQLEE--QLDN-------ETKERQAACKQVRRTEKKLKDVLLQV 1851
Query: 583 NEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
++ +R E +Q + + K++K E+ EE N KL+
Sbjct: 1852 DDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQ 1897
Score = 44.0 bits (99), Expect = 0.002
Identities = 70/384 (18%), Positives = 151/384 (39%), Gaps = 47/384 (12%)
Query: 274 IMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXE---DFDQ 330
+M ++L E QL+ E + E + ++ LE E
Sbjct: 878 LMAEKLQLQE-QLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQA 936
Query: 331 ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIA 390
E K+ Q+I++ LE+ AR+KLQ + +K ++ E
Sbjct: 937 EKKKMQQNIQELEEQLEEEESARQKLQ-----------LEKVTTEAKLKKLEEEQ----- 980
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKE 450
I +E + +EKK L++ I + T+L E E + K L + ++ E+++
Sbjct: 981 --IILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMI--------- 1029
Query: 451 LESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXX 510
TDLE R EE +R +E+++ + KL + D+
Sbjct: 1030 -----TDLEERLRR-EEKQR------QELEKTRRKLEGDST--DLSDQIAELQAQIAELK 1075
Query: 511 XXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKR 570
++ + EE + ++RE + ++++ + +R + K+
Sbjct: 1076 MQLAKKEEELQAALARVEEEAAQKNMALKKIRELES--QISELQEDLESERASRNKAEKQ 1133
Query: 571 QEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELR 630
+ + E+L+ + E++ ++S Q+ + +K+E+E+ +L + EE ++ +
Sbjct: 1134 KRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQK 1193
Query: 631 NEADIDVIITLAKYKKSLTLVLEK 654
+ ++ + + K + LEK
Sbjct: 1194 HSQAVEELAEQLEQTKRVKANLEK 1217
Score = 37.1 bits (82), Expect = 0.21
Identities = 61/337 (18%), Positives = 127/337 (37%), Gaps = 8/337 (2%)
Query: 158 ESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMA 217
E + +E+ + + + + E + L+S L + + +++ + +
Sbjct: 846 EMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRAR 905
Query: 218 LQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKD 277
L + +EL DL + E ++ + +N + +
Sbjct: 906 LTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLE 965
Query: 278 RLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQ 337
+++ E +LK E + LE + E LE + E+ + L KL
Sbjct: 966 KVT-TEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEE-EEKSKSLAKLKN 1023
Query: 338 SIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH---EMNLNIAKLIE 394
+ T LE+ EK + S + I +++ E+ + +AK E
Sbjct: 1024 KHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEE 1083
Query: 395 IEKKYNDSIEEKKTLQENIDDLRTDLLESELRV--KDLVRELDEKESILETKQCVQKELE 452
+ +EE+ Q+N+ + LES++ +DL E + + K+ + +ELE
Sbjct: 1084 ELQAALARVEEEAA-QKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELE 1142
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
+ KT+LE + L ++ +E++ LK L E
Sbjct: 1143 ALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEE 1179
Score = 34.3 bits (75), Expect = 1.5
Identities = 50/317 (15%), Positives = 118/317 (37%), Gaps = 22/317 (6%)
Query: 170 KTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMA----LQLRTKEL 225
K L M +K+ A D + D+ + K + DC+R+ ++T A + + KE
Sbjct: 1613 KKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRE-LDDTRASREEILAQAKEN 1671
Query: 226 SCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKD------RL 279
L + + ++++++ + + + A + +++ R+
Sbjct: 1672 EKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARI 1731
Query: 280 SRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSI 339
++ E +L+ + L++A + + T E+ Q+L + + +
Sbjct: 1732 AQLEEELEEEQGNTELINDRLKKANLQIDQIN-TDLNLERSHAQKNENARQQLERQNKEL 1790
Query: 340 KDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKY 399
K +E ++ K A + + + E ++ EKK
Sbjct: 1791 KVKLQEMEGTVKSKYK------ASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKL 1844
Query: 400 NDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILE----TKQCVQKELESTK 455
D + + + N + + ++ R+K L R+L+E E + +++ +Q+ELE
Sbjct: 1845 KDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDAT 1904
Query: 456 TDLEHRKTEIEEYKRLL 472
+ E+ K L
Sbjct: 1905 ETADAMNREVSSLKNKL 1921
Score = 33.9 bits (74), Expect = 2.0
Identities = 50/248 (20%), Positives = 97/248 (39%), Gaps = 8/248 (3%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLL--ESELRVKDLVRELDEKESILETKQCVQ 448
+L E+E + + EK LQE + T+L ELR + L + E E I +
Sbjct: 867 RLTEMETLQSQLMAEKLQLQEQL-QAETELCAEAEELRAR-LTAKKQELEEICHDLEARV 924
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXX 508
+E E L+ K ++++ + L E+ EE + + KL EK +
Sbjct: 925 EEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILE 984
Query: 509 XXX-XXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDN--LNDVGNMINQQRDKLF 565
E ++ + L + + L + + D+ + ++ +
Sbjct: 985 DQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQ 1044
Query: 566 ELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHN 625
EL K + + + ++I L + E + L KKE+E++ + EE N+
Sbjct: 1045 ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALK 1104
Query: 626 KL-ELRNE 632
K+ EL ++
Sbjct: 1105 KIRELESQ 1112
>BC031046-1|AAH31046.1| 495|Homo sapiens meiosis-specific nuclear
structural 1 protein.
Length = 495
Score = 50.4 bits (115), Expect = 2e-05
Identities = 67/312 (21%), Positives = 138/312 (44%), Gaps = 38/312 (12%)
Query: 333 NKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKL 392
N++ Q+ DN + LQ+ A NK +K+++ + +A
Sbjct: 40 NQMVQNENDNRVQRKQFL---RLLQNEQFELDMEEAIQKAEENKRLKELQLKQEEKLA-- 94
Query: 393 IEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELE 452
+E+ K ++S++++K +++ + + +L E E ++K + I E K ++ E
Sbjct: 95 MELAKLKHESLKDEK-MRQQVRENSIELRELEKKLKAAYMNKERAAQIAE-KDAIK--YE 150
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXX 512
K D E KT +EE+KR++ E+ D+ ++K + + D+
Sbjct: 151 QMKRDAEIAKTMMEEHKRIIKEENAAEDK-RNKAKAQYYL-DLEKQLEE----------- 197
Query: 513 XXXXXXXRESQMKSYYEELMNLKNQITQL-REFGAFDNLNDVGNM--INQQRDKLFELTK 569
+E + + YE+L+ K I ++ R+ D L + +N R + E K
Sbjct: 198 -------QEKKKQEAYEQLLKEKLMIDEIVRKIYEEDQLEKQQKLEKMNAMRRHIEEFQK 250
Query: 570 RQEEYDEKLQTK-ENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
Q + +K + + E E ++++E Q+ ++E + + E EE+ + + N L KLE
Sbjct: 251 EQALWRKKKREEMEEENRKIIEFANMQQQ---REEDRMAKVQENEEKRLQLQNALTQKLE 307
Query: 629 --LRNEADIDVI 638
LR D++ +
Sbjct: 308 EMLRQREDLEQV 319
>AF382188-1|AAK60542.1| 484|Homo sapiens NYD-SP28 protein.
Length = 484
Score = 50.4 bits (115), Expect = 2e-05
Identities = 57/212 (26%), Positives = 98/212 (46%), Gaps = 13/212 (6%)
Query: 38 KTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVA 97
KT ++ V EKS KE+E + ++ +L ++ + K+ + ++ E +I N
Sbjct: 241 KTAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRE---SEDENRYIRNDK 297
Query: 98 KLSPEQLLQLCA-GGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINW 156
+L QL +L A + +A L ++T + N L +VDK E+ L K EI
Sbjct: 298 ELVLVQLRKLKAQRTQARAASQKNL-VRLTLESNATLKALRKIVDKGEKIL-KLAEICRK 355
Query: 157 FESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDII--DCLRKNANE 214
FE+ +EK + + + KE + + K++L++L E K + D I + K N+
Sbjct: 356 FET--EEEKVLPFYSSVLTPKE---QEGIQKNNLEELTEELTKVMVDYIGMENFWKRYNK 410
Query: 215 TMALQLRTKELSCALSDLNTQNAEMRKQIHSG 246
QL + L D+N + EM KQ G
Sbjct: 411 VKLEQLSLQHRRAQLLDINGKLREMLKQYLDG 442
>AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy
polypeptide 9 protein.
Length = 1960
Score = 50.4 bits (115), Expect = 2e-05
Identities = 119/634 (18%), Positives = 247/634 (38%), Gaps = 64/634 (10%)
Query: 4 EELEIQQNQTDGCLYEDLNEQES-ITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQV 62
EEL + L E ++ E+ + E + L+ ++ ++ +++LE+ ++
Sbjct: 900 EELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESAR 959
Query: 63 MELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLD 122
+L T K+K L ++ + + + KL +++ + + T +
Sbjct: 960 QKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTT--------NLTEE 1011
Query: 123 NKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAE 182
+ + + KL N +++ EE L + ++ E + +G ST L+ +I E A+
Sbjct: 1012 EEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTD-LSDQIAELQAQ 1070
Query: 183 NDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQ 242
LK L + E + + + + A + MAL+ + +L +Q +E+++
Sbjct: 1071 IAELKMQLAKKEEELQAALARVEE---EAAQKNMALK--------KIRELESQISELQED 1119
Query: 243 IHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQ 302
+ S A+RN K L LKT +E + AA ++
Sbjct: 1120 LES-----ERASRNKAEK--------------QKRDLGEELEALKTELEDTLDSTAAQQE 1160
Query: 303 ARSESWSLERTVXXXXXXXXXXXEDFDQELN-KLTQSIKDNTTHLEDIALAREKLQSXXX 361
RS+ + E QE+ K +Q++++ LE + L+
Sbjct: 1161 LRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQ 1220
Query: 362 XXXXXXXXXSASYNKSIK---DMKHEMNLNIAKLIEIEKKYNDS------IEEKKT-LQE 411
+ ++ D +H+ A+L E++ K+N+ + +K T LQ
Sbjct: 1221 TLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQV 1280
Query: 412 NIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRL 471
+D++ L +S+ + L ++ ES L+ Q + +E K L + ++E+ K
Sbjct: 1281 ELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNS 1340
Query: 472 LFEKGEEIDELKSKLSTEKA-----IKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKS 526
E+ EE +E K L + A + D+ E +
Sbjct: 1341 FREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQR 1400
Query: 527 YYEELM---NLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKEN 583
+ E++ L+ T+L++ L+D+ ++ QR L K+Q+++D+ L ++
Sbjct: 1401 HEEKVAAYDKLEKTKTRLQQ-----ELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKT 1455
Query: 584 EIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHM 617
+ E E +KE + L EE M
Sbjct: 1456 ISAKYAEERDRAEAEAREKETKALSLARALEEAM 1489
Score = 48.0 bits (109), Expect = 1e-04
Identities = 56/283 (19%), Positives = 121/283 (42%), Gaps = 15/283 (5%)
Query: 382 KHE-MNLNIAKLIEIEKKYNDSIEE-KKTLQENIDDLRTDLLESELRVKDLVRELDEKES 439
KHE M ++ + + E+K +E+ ++ L+ + DL + E + ++ +L +L +KE
Sbjct: 1024 KHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEE 1083
Query: 440 ILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEID-ELKSKLSTEKAIKDIXXX 498
L+ + E E+ + ++ +K I E + + E E+++ E S+ EK +D+
Sbjct: 1084 ELQAA-LARVEEEAAQKNMALKK--IRELESQISELQEDLESERASRNKAEKQKRDLGEE 1140
Query: 499 XXXXXXXXXXXXXXXXXXXXXRESQ-------MKSYYEELMNLKNQITQLREFGAFDNLN 551
R + K+ EE + QI ++R+ + +
Sbjct: 1141 LEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHS-QAVE 1199
Query: 552 DVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNE 611
++ + Q + L K ++ + + NE+K L++ + EH K E +++ L
Sbjct: 1200 ELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQV 1259
Query: 612 KEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEK 654
K E + L +K+ + + ++D + L S + L K
Sbjct: 1260 KFNEGERVRTELADKV-TKLQVELDNVTGLLSQSDSKSSKLTK 1301
Score = 45.6 bits (103), Expect = 6e-04
Identities = 116/646 (17%), Positives = 256/646 (39%), Gaps = 77/646 (11%)
Query: 6 LEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMEL 65
LE Q T L E+ ++ S++++ ++ K ++E++ E++K LE Q+ L
Sbjct: 1306 LESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLE---KQIATL 1362
Query: 66 YASLRNTHRKMKLLGQKVN-LPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNK 124
+A + + +KM+ V L +AEE V + + L L E K + L+
Sbjct: 1363 HAQVADMKKKME---DSVGCLETAEE-----VKRKLQKDLEGLSQRHEEKVAAYDKLEKT 1414
Query: 125 VTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAEND 184
T +L ++ L D ++ ++ F+ L+++EK IS K + E D
Sbjct: 1415 KTRLQQELDDLLVDL-DHQRQSACNLEKKQKKFDQLLAEEKTISAK--------YAEERD 1465
Query: 185 LLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIH 244
++ + T+ L + + + + A L+ K+ + DL + ++ K +H
Sbjct: 1466 RAEAEAREKETKALSLARALEEAMEQKAE----LERLNKQFRTEMEDLMSSKDDVGKSVH 1521
Query: 245 SGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQAR 304
+ + + MK +L E +L+ + ++LE L+ +
Sbjct: 1522 ELEKSKRALEQQVEE---------------MKTQLEELEDELQATEDAKLRLEVNLQAMK 1566
Query: 305 SESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXX 364
++ ER + + +++ ++ ++D AR+KL+
Sbjct: 1567 AQ---FERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLE 1623
Query: 365 XXXXXXSASYNKSIKDMK----------HEMNLNIAKLIEIEKKYNDSIEEKKTLQENID 414
+ + +++IK ++ E++ A EI + ++ ++ K+++ +
Sbjct: 1624 AHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMI 1683
Query: 415 DLRTDLLESELRVKDLVRELDE----------KESI-LETKQCVQKELESTKTDLEHRKT 463
L+ +L +E + +E DE K ++ LE K+ ++ + + +LE +
Sbjct: 1684 QLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQG 1743
Query: 464 EIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQ 523
E L + +ID++ + L+ E++ E
Sbjct: 1744 NTELINDRLKKANLQIDQINTDLNLERS---HAQKNENARQQLERQNKELKVKLQEMEGT 1800
Query: 524 MKSYYE-ELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKE 582
+KS Y+ + L+ +I QL E DN ++R + +R E+ + + +
Sbjct: 1801 VKSKYKASITALEAKIAQLEE--QLDN-------ETKERQAACKQVRRTEKKLKDVLLQV 1851
Query: 583 NEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
++ +R E +Q + + K++K E+ EE N KL+
Sbjct: 1852 DDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQ 1897
Score = 44.0 bits (99), Expect = 0.002
Identities = 70/384 (18%), Positives = 151/384 (39%), Gaps = 47/384 (12%)
Query: 274 IMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXE---DFDQ 330
+M ++L E QL+ E + E + ++ LE E
Sbjct: 878 LMAEKLQLQE-QLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQA 936
Query: 331 ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIA 390
E K+ Q+I++ LE+ AR+KLQ + +K ++ E
Sbjct: 937 EKKKMQQNIQELEEQLEEEESARQKLQ-----------LEKVTTEAKLKKLEEEQ----- 980
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKE 450
I +E + +EKK L++ I + T+L E E + K L + ++ E+++
Sbjct: 981 --IILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMI--------- 1029
Query: 451 LESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXX 510
TDLE R EE +R +E+++ + KL + D+
Sbjct: 1030 -----TDLEERLRR-EEKQR------QELEKTRRKLEGDST--DLSDQIAELQAQIAELK 1075
Query: 511 XXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKR 570
++ + EE + ++RE + ++++ + +R + K+
Sbjct: 1076 MQLAKKEEELQAALARVEEEAAQKNMALKKIRELES--QISELQEDLESERASRNKAEKQ 1133
Query: 571 QEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELR 630
+ + E+L+ + E++ ++S Q+ + +K+E+E+ +L + EE ++ +
Sbjct: 1134 KRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQK 1193
Query: 631 NEADIDVIITLAKYKKSLTLVLEK 654
+ ++ + + K + LEK
Sbjct: 1194 HSQAVEELAEQLEQTKRVKANLEK 1217
Score = 37.1 bits (82), Expect = 0.21
Identities = 61/337 (18%), Positives = 127/337 (37%), Gaps = 8/337 (2%)
Query: 158 ESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMA 217
E + +E+ + + + + E + L+S L + + +++ + +
Sbjct: 846 EMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRAR 905
Query: 218 LQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKD 277
L + +EL DL + E ++ + +N + +
Sbjct: 906 LTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLE 965
Query: 278 RLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQ 337
+++ E +LK E + LE + E LE + E+ + L KL
Sbjct: 966 KVT-TEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEE-EEKSKSLAKLKN 1023
Query: 338 SIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH---EMNLNIAKLIE 394
+ T LE+ EK + S + I +++ E+ + +AK E
Sbjct: 1024 KHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEE 1083
Query: 395 IEKKYNDSIEEKKTLQENIDDLRTDLLESELRV--KDLVRELDEKESILETKQCVQKELE 452
+ +EE+ Q+N+ + LES++ +DL E + + K+ + +ELE
Sbjct: 1084 ELQAALARVEEEAA-QKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELE 1142
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
+ KT+LE + L ++ +E++ LK L E
Sbjct: 1143 ALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEE 1179
Score = 34.3 bits (75), Expect = 1.5
Identities = 50/317 (15%), Positives = 118/317 (37%), Gaps = 22/317 (6%)
Query: 170 KTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMA----LQLRTKEL 225
K L M +K+ A D + D+ + K + DC+R+ ++T A + + KE
Sbjct: 1613 KKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRE-LDDTRASREEILAQAKEN 1671
Query: 226 SCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKD------RL 279
L + + ++++++ + + + A + +++ R+
Sbjct: 1672 EKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARI 1731
Query: 280 SRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSI 339
++ E +L+ + L++A + + T E+ Q+L + + +
Sbjct: 1732 AQLEEELEEEQGNTELINDRLKKANLQIDQIN-TDLNLERSHAQKNENARQQLERQNKEL 1790
Query: 340 KDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKY 399
K +E ++ K A + + + E ++ EKK
Sbjct: 1791 KVKLQEMEGTVKSKYK------ASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKL 1844
Query: 400 NDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILE----TKQCVQKELESTK 455
D + + + N + + ++ R+K L R+L+E E + +++ +Q+ELE
Sbjct: 1845 KDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDAT 1904
Query: 456 TDLEHRKTEIEEYKRLL 472
+ E+ K L
Sbjct: 1905 ETADAMNREVSSLKNKL 1921
Score = 33.9 bits (74), Expect = 2.0
Identities = 50/248 (20%), Positives = 97/248 (39%), Gaps = 8/248 (3%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLL--ESELRVKDLVRELDEKESILETKQCVQ 448
+L E+E + + EK LQE + T+L ELR + L + E E I +
Sbjct: 867 RLTEMETLQSQLMAEKLQLQEQL-QAETELCAEAEELRAR-LTAKKQELEEICHDLEARV 924
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXX 508
+E E L+ K ++++ + L E+ EE + + KL EK +
Sbjct: 925 EEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILE 984
Query: 509 XXX-XXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDN--LNDVGNMINQQRDKLF 565
E ++ + L + + L + + D+ + ++ +
Sbjct: 985 DQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQ 1044
Query: 566 ELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHN 625
EL K + + + ++I L + E + L KKE+E++ + EE N+
Sbjct: 1045 ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALK 1104
Query: 626 KL-ELRNE 632
K+ EL ++
Sbjct: 1105 KIRELESQ 1112
>Y12490-1|CAA73095.1| 1979|Homo sapiens Golgi-associated
microtubule-binding protein protein.
Length = 1979
Score = 50.0 bits (114), Expect = 3e-05
Identities = 123/593 (20%), Positives = 238/593 (40%), Gaps = 68/593 (11%)
Query: 42 QEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSP 101
QE V+ +K EL++ Q E + +RN M+ L Q N + L + +
Sbjct: 596 QESNVSIQKENLELKEHIRQNEEELSRIRN--ELMQSLNQDSNSNFKDTL--LKEREAEV 651
Query: 102 EQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLM 161
L Q + E + L + KV FDV K+ N LV CE+ + +E + L
Sbjct: 652 RNLKQNLS--ELEQLNENL--KKVAFDV-KMEN--EKLVLACEDVRHQLEECLAGNNQL- 703
Query: 162 SQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLR 221
S EK +TL M+ E AE K L + ++ K I ++ + +N N T ALQL
Sbjct: 704 SLEKNTIVETLKMEKGEIEAELCWAKKRLLEEANKYEKTIEELSNA--RNLN-TSALQLE 760
Query: 222 TKELSCALSDLNTQNAEMRKQIHS--GDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRL 279
+ L + + AE++K I DH + I ++L
Sbjct: 761 HEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKL 820
Query: 280 SRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQ--ELNKLTQ 337
+L+ +++ Q E R +R++ E+ ++ E T
Sbjct: 821 KERSSKLQEELDKYSQALRKNEILRQTIEEKDRSLGSMKEENNHLQEELERLREEQSRTA 880
Query: 338 SIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEK 397
+ D T LA E Q +++ I + +++ + + + ++ +K
Sbjct: 881 PVADPKTLDSVTELASEVSQ---LNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQK 937
Query: 398 KYNDSIEEKKTLQENIDDLRTDL-LESELRVKDLVRELDEKESILETKQCVQKELESTKT 456
K ++E + E ++ T L LE + +K L + +++ ++ L ++ +++++ +
Sbjct: 938 K---EMDEFRYQHEQMNATHTQLFLEKDEEIKSLQKTIEQIKTQLHEER---QDIQTDNS 991
Query: 457 DLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXX 516
D+ ++T+++ L E G E +L SK TE+ +K I
Sbjct: 992 DI-FQETKVQS---LNIENGSEKHDL-SKAETERLVKGIKE------------------- 1027
Query: 517 XXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDE 576
RE ++K E+ ++L QI QL + ++VG + + K E+
Sbjct: 1028 ---RELEIKLLNEKNISLTKQIDQLSK-------DEVGKLTQIIQQKDLEIQALHARISS 1077
Query: 577 KLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLEL 629
T++ +V + + ++EK +LNEK E+ ++ H +++
Sbjct: 1078 TSHTQD-----VVYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMDI 1125
Score = 49.2 bits (112), Expect = 5e-05
Identities = 111/615 (18%), Positives = 256/615 (41%), Gaps = 56/615 (9%)
Query: 21 LNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRK----- 75
LN+ S+ ++ K+ V +++ + K+EL+ ++ Y +++T +
Sbjct: 407 LNQDNSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKSTATRDISLD 466
Query: 76 MKLLGQKVNLPSAE-ELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLN 134
+L ++NL + E EL+ K + ++ +A +H L + ++K N
Sbjct: 467 SELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMIL---IKDQLSKQQN 523
Query: 135 IPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLR 194
+S++ K ++ L K+ ++ E +K TK L ++ KE ++++ + L +
Sbjct: 524 EGDSIISKLKQDLNDEKKRVHQLED----DKMDITKELDVQ-KEKLIQSEVALNDLHLTK 578
Query: 195 TEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYAN 254
+ ++ +++D L K+ +++Q EL + QN E +I
Sbjct: 579 QKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIR----QNEEELSRI----------- 623
Query: 255 RNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTV 314
RN +++K+R + + LK N+ + QL L++ + +
Sbjct: 624 RNELMQSLNQDSNSNFKDTLLKEREAEVRN-LKQNLSELEQLNENLKKVAFDVKMENEKL 682
Query: 315 XXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASY 374
E+ N+L S++ NT +E + + + ++++ + Y
Sbjct: 683 VLACEDVRHQLEECLAGNNQL--SLEKNTI-VETLKMEKGEIEAELCWAKKRLLEEANKY 739
Query: 375 NKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKK-----TLQENIDDLRT------DLLES 423
K+I+++ + NLN + L ++E ++ + +KK L++NI+ + T D+L S
Sbjct: 740 EKTIEELSNARNLNTSAL-QLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLSS 798
Query: 424 EL-RVKDLVRELDEK----ESILETKQCVQKELESTKTDL---EHRKTEIEEYKRLLFEK 475
L K L + +++K E + E +Q+EL+ L E + IEE R L
Sbjct: 799 SLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTIEEKDRSLGSM 858
Query: 476 GEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLK 535
EE + L+ +L + +++ + + +K + EE +
Sbjct: 859 KEENNHLQEEL---ERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEIKHH 915
Query: 536 NQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQ 595
+I + + L + + + ++ + + + K+ EIK L +++ +
Sbjct: 916 QKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDEEIKSLQKTIEQI 975
Query: 596 EHVLNKKEKEIKMLN 610
+ L+++ ++I+ N
Sbjct: 976 KTQLHEERQDIQTDN 990
Score = 36.3 bits (80), Expect = 0.37
Identities = 20/73 (27%), Positives = 39/73 (53%), Gaps = 1/73 (1%)
Query: 404 EEKKTLQENIDDLRTDLLESELRVKDLVRELDE-KESILETKQCVQKELESTKTDLEHRK 462
E + LQ+ +++LR L E + ++ L +SI T + +KE E T ++++ K
Sbjct: 1340 ESSELLQQELEELRKSLQEKDATIRTLQENNHRLSDSIAATSELERKEHEQTDSEIKQLK 1399
Query: 463 TEIEEYKRLLFEK 475
+ + ++LL EK
Sbjct: 1400 EKQDVLQKLLKEK 1412
Score = 34.3 bits (75), Expect = 1.5
Identities = 58/275 (21%), Positives = 113/275 (41%), Gaps = 39/275 (14%)
Query: 380 DMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESE----------LRVKD 429
D+ E+++ KLI+ E ND K+ L++ +++L L +S+ L +K+
Sbjct: 552 DITKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKE 611
Query: 430 LVRELDEKESIL--ETKQCVQKELESTKTD--LEHRKTEIEEYKRLLFEKGEEIDELKS- 484
+R+ +E+ S + E Q + ++ S D L+ R+ E+ K+ L E + + LK
Sbjct: 612 HIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSELEQLNENLKKV 671
Query: 485 ----KLSTEK---AIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQ 537
K+ EK A +D+ + + EL K +
Sbjct: 672 AFDVKMENEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKR 731
Query: 538 ITQ--------LREFGAFDNLNDVGNM--------INQQRD-KLFELTKRQEEYDEKLQT 580
+ + + E NLN +NQ++D ++ EL K E+ D +
Sbjct: 732 LLEEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKE 791
Query: 581 KENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEE 615
++ + +E + ++NKKE I+ L E+ +
Sbjct: 792 TKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSK 826
Score = 33.9 bits (74), Expect = 2.0
Identities = 19/75 (25%), Positives = 40/75 (53%), Gaps = 1/75 (1%)
Query: 3 QEELE-IQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQ 61
QEELE +++ Q+ D +S+T + ++++L T+ + + +K +ED+
Sbjct: 866 QEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQS 925
Query: 62 VMELYASLRNTHRKM 76
M+L SL+ ++M
Sbjct: 926 KMQLLQSLQEQKKEM 940
Score = 31.9 bits (69), Expect = 8.0
Identities = 51/254 (20%), Positives = 110/254 (43%), Gaps = 19/254 (7%)
Query: 388 NIAKLIEIEKKYNDSIEEKKTLQE-NIDD-LRTDLLESELRVKDLVRELD----EKESIL 441
++ ++ +++ +D+ E L N D+ L D L+ ++R++ L +E EKE +
Sbjct: 383 SVEEVFRLQQALSDAENEIMRLSSLNQDNSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQ 442
Query: 442 ETKQCVQKELE---STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA-IKDIXX 497
+ + E E ST T +E+ + + L K +E+++ S+ T A I+++
Sbjct: 443 MSLLKLNNEYEVIKSTATRDISLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDR 502
Query: 498 XXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMI 557
+S + ++L + K ++ QL D+ D+ +
Sbjct: 503 QNQEATKHMILIKDQLSKQQNEGDSIISKLKQDLNDEKKRVHQLE-----DDKMDITKEL 557
Query: 558 NQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEH---VLNKKEKEIK-MLNEKE 613
+ Q++KL + + Q E++++ LV+ + + + + K+ E+K + + E
Sbjct: 558 DVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNE 617
Query: 614 EEHMNIINLLHNKL 627
EE I N L L
Sbjct: 618 EELSRIRNELMQSL 631
>X66397-1|CAA47021.1| 2349|Homo sapiens Tpr protein.
Length = 2349
Score = 50.0 bits (114), Expect = 3e-05
Identities = 60/270 (22%), Positives = 114/270 (42%), Gaps = 34/270 (12%)
Query: 394 EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESI-LETKQCV---QK 449
+IEK ++ KK L+ ++ T ++++ D R+LD + ++ L TK+ + QK
Sbjct: 840 QIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQK 899
Query: 450 ELESTKTDLEHRKTEIEEYKRLLFEKG-----EEIDELKSKL-STEKAIKDIXXXXXXXX 503
E+ + K L + + ++ KG E++D+L S+L TE+ + D+
Sbjct: 900 EIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDL-------- 951
Query: 504 XXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDK 563
+ M + EE +N + Q+T+ L + Q K
Sbjct: 952 ----KERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKK 1007
Query: 564 LFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLL 623
L E+ K ++E +++ +R +ESM +Q L K ++ NE +E L
Sbjct: 1008 LMEVEKEKQEL-------QDDKRRAIESMEQQLSELKKTLSSVQ--NEVQEALQRASTAL 1058
Query: 624 HNKLELRNEADIDVIITLA---KYKKSLTL 650
N+ + R + I + KY++ L L
Sbjct: 1059 SNEQQARRDCQEQAKIAVEAQNKYERELML 1088
Score = 42.7 bits (96), Expect = 0.004
Identities = 58/291 (19%), Positives = 122/291 (41%), Gaps = 23/291 (7%)
Query: 331 ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIA 390
EL KL +K T +++ +A+++ + A I+ ++ +
Sbjct: 81 ELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRT-NERLSQELE 139
Query: 391 KLIEIEKKYNDSIEEKKT----LQENIDDLRTDLLESELRVKDLVRELDEKESILETKQC 446
L E K+ N+ ++E T LQ +D+L+ S++ VK + L++++ +L ++
Sbjct: 140 YLTEDVKRLNEKLKESNTTKGELQLKLDELQA----SDVSVKYREKRLEQEKELLHSQNT 195
Query: 447 VQKELESTKTD----LEHRK-TEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXX 501
TKTD L K EI E K L K EE+ L+ +++ K +
Sbjct: 196 WLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNE------- 248
Query: 502 XXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQR 561
+++ M+ + +N +++ L + A D+ N + +
Sbjct: 249 HLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYK-SAADDSEAKSNELTRAV 307
Query: 562 DKLFELTKRQEEYDEKLQTKENEIKRLVESM-TEQEHVLNKKEKEIKMLNE 611
++L +L K E ++ +Q E+++ + M E + + EKE++ N+
Sbjct: 308 EELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMLEKIGRLEKELENAND 358
Score = 41.5 bits (93), Expect = 0.010
Identities = 119/666 (17%), Positives = 262/666 (39%), Gaps = 59/666 (8%)
Query: 2 KQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFE------KSKKEL 55
+Q E + + + L +L + I S TK + Q + + E K + E+
Sbjct: 800 QQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEV 859
Query: 56 EDRQNQVMELYASLRNTHRKMKL-----LGQKVNLPSAEE------LHIMNVAKLSPEQL 104
E R L L +T R++ L K L +A++ H+ N+ Q
Sbjct: 860 EQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQS 919
Query: 105 LQLCAGGEPKALEHSTLDNKVTF--DVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMS 162
Q G+P E +D+ V+ + +N + + + + ++ E ++
Sbjct: 920 SQRTGKGQPSNKED--VDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLN 977
Query: 163 QEKGIST---KTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQ 219
+EK ++ K + +++KE +AE ++ L++ E KE ++ D R+ A E+M Q
Sbjct: 978 KEKQVTEEVRKNIEVRLKE-SAE---FQTQLEKKLMEVEKEKQELQDDKRR-AIESMEQQ 1032
Query: 220 LRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRL 279
L EL LS + + E ++ + + A R+ +
Sbjct: 1033 L--SELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHA 1090
Query: 280 SRAE--HQLKTNVERVVQLEAALEQA--RSESWSLERTVXXXXXXXXXXXEDFD-----Q 330
+ E K V ++ + LE+ ++ES LE E +
Sbjct: 1091 ADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCE 1150
Query: 331 ELNKLTQSIKDNTTHLED--IALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLN 388
+L K + + D L D +A +E +Q + ++ ++ E +
Sbjct: 1151 DLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIA 1210
Query: 389 IAK--LIEIEK-KYNDSIEE-KKTLQENIDDLRTDLLESELRVK------DLVRELDEKE 438
+ + ++E +Y +E ++ LQE D L + + ++ K +L+++ +
Sbjct: 1211 ETRFEVAQVESLRYRQRVELLERELQELEDSLNAEREKVQVTAKTMAQHEELMKKTETMN 1270
Query: 439 SILETKQCVQKELESTKTDLEHRKTEIEEYK---RLLFEKGEEIDELKSKLSTEKAI--K 493
++ET + +++E E + DL+ + ++ + + L E E+ E L EK + +
Sbjct: 1271 VVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEE 1330
Query: 494 DIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDN--LN 551
D+ S+ + + + + L +I +L+ A N L
Sbjct: 1331 DVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLT 1390
Query: 552 DVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNE 611
+ N+I ++ L ++ +E + L K +I+ V+++T+ + + + + + + L
Sbjct: 1391 NNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKA 1450
Query: 612 KEEEHM 617
++++ M
Sbjct: 1451 QQDKVM 1456
Score = 35.9 bits (79), Expect = 0.49
Identities = 49/263 (18%), Positives = 108/263 (41%), Gaps = 14/263 (5%)
Query: 401 DSIEEK---KTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQC-VQKELESTKT 456
++IE K K LQE ++ + + E+E + + +L E+ + L ++ + +L+
Sbjct: 664 EAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASK 723
Query: 457 DLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXX 516
E + +E Y+R + E +L + ++ I +
Sbjct: 724 RYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIIN-TMTQDLRGANEKLAVAEVRAE 782
Query: 517 XXXRESQMKSYYEELMNLKNQITQLREFGA---FDNLNDVGNMINQQRDKLFELTKRQEE 573
+E +M E ++ + + + G NL + ++ + E +R
Sbjct: 783 NLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSET---ETKQRLSS 839
Query: 574 YDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEA 633
EKL+ + + +K+ +E+ EQ H L + ++++L+ K + NL N EL A
Sbjct: 840 QIEKLEHEISHLKKKLENEVEQRHTLT-RNLDVQLLDTKRQLDTE-TNLHLNTKELLKNA 897
Query: 634 DIDVIITLAKYKKSLTLVLEKMS 656
+ I TL ++ ++ + + S
Sbjct: 898 QKE-IATLKQHLSNMEVQVASQS 919
Score = 34.7 bits (76), Expect = 1.1
Identities = 48/252 (19%), Positives = 105/252 (41%), Gaps = 11/252 (4%)
Query: 379 KDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKE 438
K+++ + NIA + + + EK+ L + L +L VK L +L E
Sbjct: 97 KELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESN 156
Query: 439 SILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEID-ELKSKLSTEKAIKDIXX 497
+ Q EL+++ +++R+ +E+ K LL + ++ ELK+K A+
Sbjct: 157 TTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKG 216
Query: 498 XXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELM-NLKNQITQLREFGAFDNLNDVGNM 556
+ + +K+ E L ++++ +T+L+E A + +
Sbjct: 217 NEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKE--AKEQQASMEEK 274
Query: 557 INQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEH 616
+ + + +L+ + + + K NE+ R VE L+K KE N+ ++H
Sbjct: 275 FHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEE-------LHKLLKEAGEANKAIQDH 327
Query: 617 MNIINLLHNKLE 628
+ + +++E
Sbjct: 328 LLEVEQSKDQME 339
Score = 32.3 bits (70), Expect = 6.1
Identities = 39/167 (23%), Positives = 74/167 (44%), Gaps = 17/167 (10%)
Query: 57 DRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKAL 116
++ N+++EL +L N ++ L +++N H+ K + L +L E +A
Sbjct: 214 EKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQ---KHVEDLLTKLKEAKEQQAS 270
Query: 117 EHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESL--MSQEKGISTKTLTM 174
N++ + KL N+ S D E K E+ E L + +E G + K +
Sbjct: 271 MEEKFHNELNAHI-KLSNLYKSAADDSEA---KSNELTRAVEELHKLLKEAGEANKAIQD 326
Query: 175 KIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLR 221
+ E ++ S DQ+ E L++I + L +NAN+ ++ R
Sbjct: 327 HLLE-------VEQSKDQMEKEMLEKIGRLEKEL-ENANDLLSATKR 365
>U69668-1|AAB48030.1| 2363|Homo sapiens Tpr protein.
Length = 2363
Score = 50.0 bits (114), Expect = 3e-05
Identities = 60/270 (22%), Positives = 114/270 (42%), Gaps = 34/270 (12%)
Query: 394 EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESI-LETKQCV---QK 449
+IEK ++ KK L+ ++ T ++++ D R+LD + ++ L TK+ + QK
Sbjct: 840 QIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQK 899
Query: 450 ELESTKTDLEHRKTEIEEYKRLLFEKG-----EEIDELKSKL-STEKAIKDIXXXXXXXX 503
E+ + K L + + ++ KG E++D+L S+L TE+ + D+
Sbjct: 900 EIATLKRHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDL-------- 951
Query: 504 XXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDK 563
+ M + EE +N + Q+T+ L + Q K
Sbjct: 952 ----KERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKK 1007
Query: 564 LFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLL 623
L E+ K ++E +++ +R +ESM +Q L K ++ NE +E L
Sbjct: 1008 LMEVEKEKQEL-------QDDKRRAIESMEQQLSELKKTLSSVQ--NEVQEALQRASTAL 1058
Query: 624 HNKLELRNEADIDVIITLA---KYKKSLTL 650
N+ + R + I + KY++ L L
Sbjct: 1059 SNEQQARRDCQEQAKIAVEAQNKYERELML 1088
Score = 42.7 bits (96), Expect = 0.004
Identities = 58/291 (19%), Positives = 122/291 (41%), Gaps = 23/291 (7%)
Query: 331 ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIA 390
EL KL +K T +++ +A+++ + A I+ ++ +
Sbjct: 81 ELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRT-NERLSQELE 139
Query: 391 KLIEIEKKYNDSIEEKKT----LQENIDDLRTDLLESELRVKDLVRELDEKESILETKQC 446
L E K+ N+ ++E T LQ +D+L+ S++ VK + L++++ +L ++
Sbjct: 140 YLTEDVKRLNEKLKESNTTKGELQLKLDELQA----SDVSVKYREKRLEQEKELLHSQNT 195
Query: 447 VQKELESTKTD----LEHRK-TEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXX 501
TKTD L K EI E K L K EE+ L+ +++ K +
Sbjct: 196 WLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNE------- 248
Query: 502 XXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQR 561
+++ M+ + +N +++ L + A D+ N + +
Sbjct: 249 HLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYK-SAADDSEAKSNELTRAV 307
Query: 562 DKLFELTKRQEEYDEKLQTKENEIKRLVESM-TEQEHVLNKKEKEIKMLNE 611
++L +L K E ++ +Q E+++ + M E + + EKE++ N+
Sbjct: 308 EELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMLEKIGRLEKELENAND 358
Score = 41.5 bits (93), Expect = 0.010
Identities = 119/666 (17%), Positives = 262/666 (39%), Gaps = 59/666 (8%)
Query: 2 KQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFE------KSKKEL 55
+Q E + + + L +L + I S TK + Q + + E K + E+
Sbjct: 800 QQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEV 859
Query: 56 EDRQNQVMELYASLRNTHRKMKL-----LGQKVNLPSAEE------LHIMNVAKLSPEQL 104
E R L L +T R++ L K L +A++ H+ N+ Q
Sbjct: 860 EQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKRHLSNMEVQVASQS 919
Query: 105 LQLCAGGEPKALEHSTLDNKVTF--DVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMS 162
Q G+P E +D+ V+ + +N + + + + ++ E ++
Sbjct: 920 SQRTGKGQPSNKED--VDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLN 977
Query: 163 QEKGIST---KTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQ 219
+EK ++ K + +++KE +AE ++ L++ E KE ++ D R+ A E+M Q
Sbjct: 978 KEKQVTEEVRKNIEVRLKE-SAE---FQTQLEKKLMEVEKEKQELQDDKRR-AIESMEQQ 1032
Query: 220 LRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRL 279
L EL LS + + E ++ + + A R+ +
Sbjct: 1033 L--SELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHA 1090
Query: 280 SRAE--HQLKTNVERVVQLEAALEQA--RSESWSLERTVXXXXXXXXXXXEDFD-----Q 330
+ E K V ++ + LE+ ++ES LE E +
Sbjct: 1091 ADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCE 1150
Query: 331 ELNKLTQSIKDNTTHLED--IALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLN 388
+L K + + D L D +A +E +Q + ++ ++ E +
Sbjct: 1151 DLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIA 1210
Query: 389 IAK--LIEIEK-KYNDSIEE-KKTLQENIDDLRTDLLESELRVK------DLVRELDEKE 438
+ + ++E +Y +E ++ LQE D L + + ++ K +L+++ +
Sbjct: 1211 ETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMN 1270
Query: 439 SILETKQCVQKELESTKTDLEHRKTEIEEYK---RLLFEKGEEIDELKSKLSTEKAI--K 493
++ET + +++E E + DL+ + ++ + + L E E+ E L EK + +
Sbjct: 1271 VVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEE 1330
Query: 494 DIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDN--LN 551
D+ S+ + + + + L +I +L+ A N L
Sbjct: 1331 DVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLT 1390
Query: 552 DVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNE 611
+ N+I ++ L ++ +E + L K +I+ V+++T+ + + + + + + L
Sbjct: 1391 NNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKA 1450
Query: 612 KEEEHM 617
++++ M
Sbjct: 1451 QQDKVM 1456
Score = 36.3 bits (80), Expect = 0.37
Identities = 49/263 (18%), Positives = 108/263 (41%), Gaps = 14/263 (5%)
Query: 401 DSIEEK---KTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQC-VQKELESTKT 456
++IE K K LQE ++ + + E+E + + +L E+ + L ++ + +L+
Sbjct: 664 EAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASK 723
Query: 457 DLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXX 516
E + +E Y+R + E +L + ++ I +
Sbjct: 724 RYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIIN-TMTQDLRGANEKLAVAEIRAE 782
Query: 517 XXXRESQMKSYYEELMNLKNQITQLREFGA---FDNLNDVGNMINQQRDKLFELTKRQEE 573
+E +M E ++ + + + G NL + ++ + E +R
Sbjct: 783 NLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSET---ETKQRLSS 839
Query: 574 YDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEA 633
EKL+ + + +K+ +E+ EQ H L + ++++L+ K + NL N EL A
Sbjct: 840 QIEKLEHEISHLKKKLENEVEQRHTLT-RNLDVQLLDTKRQLDTE-TNLHLNTKELLKNA 897
Query: 634 DIDVIITLAKYKKSLTLVLEKMS 656
+ I TL ++ ++ + + S
Sbjct: 898 QKE-IATLKRHLSNMEVQVASQS 919
Score = 34.7 bits (76), Expect = 1.1
Identities = 48/252 (19%), Positives = 105/252 (41%), Gaps = 11/252 (4%)
Query: 379 KDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKE 438
K+++ + NIA + + + EK+ L + L +L VK L +L E
Sbjct: 97 KELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESN 156
Query: 439 SILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEID-ELKSKLSTEKAIKDIXX 497
+ Q EL+++ +++R+ +E+ K LL + ++ ELK+K A+
Sbjct: 157 TTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKG 216
Query: 498 XXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELM-NLKNQITQLREFGAFDNLNDVGNM 556
+ + +K+ E L ++++ +T+L+E A + +
Sbjct: 217 NEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKE--AKEQQASMEEK 274
Query: 557 INQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEH 616
+ + + +L+ + + + K NE+ R VE L+K KE N+ ++H
Sbjct: 275 FHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEE-------LHKLLKEAGEANKAIQDH 327
Query: 617 MNIINLLHNKLE 628
+ + +++E
Sbjct: 328 LLEVEQSKDQME 339
Score = 32.3 bits (70), Expect = 6.1
Identities = 39/167 (23%), Positives = 74/167 (44%), Gaps = 17/167 (10%)
Query: 57 DRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKAL 116
++ N+++EL +L N ++ L +++N H+ K + L +L E +A
Sbjct: 214 EKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQ---KHVEDLLTKLKEAKEQQAS 270
Query: 117 EHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESL--MSQEKGISTKTLTM 174
N++ + KL N+ S D E K E+ E L + +E G + K +
Sbjct: 271 MEEKFHNELNAHI-KLSNLYKSAADDSEA---KSNELTRAVEELHKLLKEAGEANKAIQD 326
Query: 175 KIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLR 221
+ E ++ S DQ+ E L++I + L +NAN+ ++ R
Sbjct: 327 HLLE-------VEQSKDQMEKEMLEKIGRLEKEL-ENANDLLSATKR 365
>D86970-1|BAA13206.2| 2067|Homo sapiens KIAA0216 protein.
Length = 2067
Score = 50.0 bits (114), Expect = 3e-05
Identities = 58/346 (16%), Positives = 147/346 (42%), Gaps = 17/346 (4%)
Query: 275 MKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNK 334
+K +L + + ++VV LEA L+ S+ E ++ D + ++
Sbjct: 1511 LKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQL----RDLEAKVKD 1566
Query: 335 LTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKL-I 393
+ + + ++ + A+ +L+ S ++ +++ + + ++ +
Sbjct: 1567 QEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEV 1626
Query: 394 EIEKKYNDS---IEEKKTLQENIDDLRTDLLESELRV-KDLVRELDEKESILETKQCVQK 449
++E++Y D + EK+ L+ + L + + K L ++L +++L Q +
Sbjct: 1627 QLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLD 1686
Query: 450 ELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE-LKSKLSTEKAIKDIXXXXXXXXXXXXX 508
L+++ K EI + K L E +K++ + E I+D+
Sbjct: 1687 HLKNSAPS----KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTA 1742
Query: 509 XXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELT 568
+ +++++ EE N++ + + D+ IN + +L E
Sbjct: 1743 LEEQLSRLQREK-NEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQ-INDLQAQLEEAN 1800
Query: 569 KRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEE 614
K ++E EKLQ +++++ L +SM ++ +++++E +I+ L + E
Sbjct: 1801 KEKQELQEKLQALQSQVEFLEQSMVDKS-LVSRQEAKIRELETRLE 1845
Score = 35.9 bits (79), Expect = 0.49
Identities = 45/263 (17%), Positives = 106/263 (40%), Gaps = 14/263 (5%)
Query: 394 EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELES 453
E E K + K+ L+ + DL+ D ES+ ++ L ++ Q + EL+
Sbjct: 1405 EFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC----------QRLTAELQD 1454
Query: 454 TKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXX 513
TK LE ++ E ++ E+ + + EK ++
Sbjct: 1455 TKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQRE---KLQREKDMLLAEAFSL 1511
Query: 514 XXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEE 573
++ + + +++++L+ ++ + + D + + + Q RD ++ ++EE
Sbjct: 1512 KQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEAS-LAKVKKQLRDLEAKVKDQEEE 1570
Query: 574 YDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEA 633
DE+ T + + + E E + KE++ +E+ EE ++E++ E
Sbjct: 1571 LDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1630
Query: 634 DIDVIITLAKYKKSLTLVLEKMS 656
+ + + + K+ L L +S
Sbjct: 1631 EYEDKQKVLREKRELEGKLATLS 1653
Score = 35.5 bits (78), Expect = 0.65
Identities = 44/235 (18%), Positives = 94/235 (40%), Gaps = 20/235 (8%)
Query: 378 IKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEK 437
+K+ E A ++ K IE+ L IDD+ E ++ L RE +E
Sbjct: 1701 LKNQLEESEFTCAAAVKARKAMEVEIED---LHLQIDDIAKAKTALEEQLSRLQREKNEI 1757
Query: 438 ESILETKQCVQKEL----ESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIK 493
++ LE Q EL ++ +I + + L E +E EL+ KL ++
Sbjct: 1758 QNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQV 1817
Query: 494 DIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDV 553
+ +E++++ L + Q+ +L + L +
Sbjct: 1818 EFLEQSMVDKSLVSR-----------QEAKIRELETRLEFERTQVKRLESLAS--RLKEN 1864
Query: 554 GNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM 608
+ ++RD+ R++E +++LQ + + K + + +E ++K+ E++M
Sbjct: 1865 MEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEM 1919
>BX641024-1|CAE46015.1| 1694|Homo sapiens hypothetical protein
protein.
Length = 1694
Score = 50.0 bits (114), Expect = 3e-05
Identities = 123/593 (20%), Positives = 238/593 (40%), Gaps = 68/593 (11%)
Query: 42 QEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSP 101
QE V+ +K EL++ Q E + +RN M+ L Q N + L + +
Sbjct: 311 QESNVSIQKENLELKEHIRQNEEELSRIRN--ELMQSLNQDSNSNFKDTL--LKEREAEV 366
Query: 102 EQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLM 161
L Q + E + L + KV FDV K+ N LV CE+ + +E + L
Sbjct: 367 RNLKQNLS--ELEQLNENL--KKVAFDV-KMEN--EKLVLACEDVRHQLEECLAGNNQL- 418
Query: 162 SQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLR 221
S EK +TL M+ E AE K L + ++ K I ++ + +N N T ALQL
Sbjct: 419 SLEKNTIVETLKMEKGEIEAELCWAKKRLLEEANKYEKTIEELSNA--RNLN-TSALQLE 475
Query: 222 TKELSCALSDLNTQNAEMRKQIHS--GDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRL 279
+ L + + AE++K I DH + I ++L
Sbjct: 476 HEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKL 535
Query: 280 SRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQ--ELNKLTQ 337
+L+ +++ Q E R +R++ E+ ++ E T
Sbjct: 536 KERSSKLQEELDKYSQALRKNEILRQTIEEKDRSLGSMKEENNHLQEELERLREEQSRTA 595
Query: 338 SIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEK 397
+ D T LA E Q +++ I + +++ + + + ++ +K
Sbjct: 596 PVADPKTLDSVTELASEVSQ---LNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQK 652
Query: 398 KYNDSIEEKKTLQENIDDLRTDL-LESELRVKDLVRELDEKESILETKQCVQKELESTKT 456
K ++E + E ++ T L LE + +K L + +++ ++ L ++ +++++ +
Sbjct: 653 K---EMDEFRYQHEQMNATHTQLFLEKDEEIKSLQKTIEQIKTQLHEER---QDIQTDNS 706
Query: 457 DLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXX 516
D+ ++T+++ L E G E +L SK TE+ +K I
Sbjct: 707 DI-FQETKVQS---LNIENGSEKHDL-SKAETERLVKGIKE------------------- 742
Query: 517 XXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDE 576
RE ++K E+ ++L QI QL + ++VG + + K E+
Sbjct: 743 ---RELEIKLLNEKNISLTKQIDQLSK-------DEVGKLTQIIQQKDLEIQALHARISS 792
Query: 577 KLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLEL 629
T++ +V + + ++EK +LNEK E+ ++ H +++
Sbjct: 793 TSHTQD-----VVYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMDI 840
Score = 46.8 bits (106), Expect = 3e-04
Identities = 116/638 (18%), Positives = 260/638 (40%), Gaps = 62/638 (9%)
Query: 5 ELEIQQNQTDGCLYED-LNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVM 63
+LE + Q D + E+E I ++S + ++ + Q+ + E L + +
Sbjct: 98 KLECSKLQPSAVKQSDTMTEKERILAQSASVEEVFRL-QQALSDAENEIMRLSSLNQEEL 156
Query: 64 EL-YASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLL-QLCAGGEPKALEHSTL 121
++ L N + +K + ++ ELH + + + EQ L Q + E E L
Sbjct: 157 QMSLLKLNNEYEVIKSTATR-DISLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEEL 215
Query: 122 DNK----------VTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKT 171
D + + ++K N +S++ K ++ L K+ ++ E +K TK
Sbjct: 216 DRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQDLNDEKKRVHQLED----DKMDITKE 271
Query: 172 LTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSD 231
L ++ KE ++++ + L + + ++ +++D L K+ +++Q EL +
Sbjct: 272 LDVQ-KEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIR- 329
Query: 232 LNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVE 291
QN E +I RN +++K+R + + LK N+
Sbjct: 330 ---QNEEELSRI-----------RNELMQSLNQDSNSNFKDTLLKEREAEVRN-LKQNLS 374
Query: 292 RVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIAL 351
+ QL L++ + + E+ N+L S++ NT +E + +
Sbjct: 375 ELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEECLAGNNQL--SLEKNTI-VETLKM 431
Query: 352 AREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKK---- 407
+ ++++ + Y K+I+++ + NLN + L ++E ++ + +KK
Sbjct: 432 EKGEIEAELCWAKKRLLEEANKYEKTIEELSNARNLNTSAL-QLEHEHLIKLNQKKDMEI 490
Query: 408 -TLQENIDDLRT------DLLESEL-RVKDLVRELDEK----ESILETKQCVQKELESTK 455
L++NI+ + T D+L S L K L + +++K E + E +Q+EL+
Sbjct: 491 AELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYS 550
Query: 456 TDL---EHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXX 512
L E + IEE R L EE + L+ +L + +++
Sbjct: 551 QALRKNEILRQTIEEKDRSLGSMKEENNHLQEEL---ERLREEQSRTAPVADPKTLDSVT 607
Query: 513 XXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQE 572
+ + +K + EE + +I + + L + + + ++ +
Sbjct: 608 ELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNA 667
Query: 573 EYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLN 610
+ + K+ EIK L +++ + + L+++ ++I+ N
Sbjct: 668 THTQLFLEKDEEIKSLQKTIEQIKTQLHEERQDIQTDN 705
Score = 37.5 bits (83), Expect = 0.16
Identities = 50/248 (20%), Positives = 107/248 (43%), Gaps = 20/248 (8%)
Query: 404 EEKKTLQENIDDLRTDLLESELRVKDLVRELDE-KESILETKQCVQKELESTKTDLEHRK 462
E + LQ+ +++LR L E + ++ L +SI T + +KE E T ++++ K
Sbjct: 1055 ESSELLQQELEELRKSLQEKDATIRTLQENNHRLSDSIAATSELERKEHEQTDSEIKQLK 1114
Query: 463 TEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRES 522
+ + ++LL EK I +L +
Sbjct: 1115 EKQDVLQKLLKEKDLLIKAKSDQLLSSNENFTNKVNENELLRQAVTNLKERILILEMDIG 1174
Query: 523 QMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEE---YDEKLQ 579
++K E++ ++ + E+ A N +M+ R+K FE +E+ +++ L+
Sbjct: 1175 KLKGENEKI--VETYRGKETEYQALQETNMKFSMM--LREKEFECHSMKEKALAFEQLLK 1230
Query: 580 TKE-------NEIKRLVESMTEQEHVLNKKEKEIKM-LNEKEEEH---MNIINLLHNKLE 628
KE N++ V+SM E+ V ++ ++ + L +K+ E+ N++ L +K E
Sbjct: 1231 EKEQGKTGELNQLLNAVKSMQEKTVVFQQERDQVMLALKQKQMENTALQNVVQRLRDK-E 1289
Query: 629 LRNEADID 636
R+ +++
Sbjct: 1290 FRSNQELE 1297
Score = 34.3 bits (75), Expect = 1.5
Identities = 58/275 (21%), Positives = 113/275 (41%), Gaps = 39/275 (14%)
Query: 380 DMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESE----------LRVKD 429
D+ E+++ KLI+ E ND K+ L++ +++L L +S+ L +K+
Sbjct: 267 DITKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKE 326
Query: 430 LVRELDEKESIL--ETKQCVQKELESTKTD--LEHRKTEIEEYKRLLFEKGEEIDELKS- 484
+R+ +E+ S + E Q + ++ S D L+ R+ E+ K+ L E + + LK
Sbjct: 327 HIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSELEQLNENLKKV 386
Query: 485 ----KLSTEK---AIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQ 537
K+ EK A +D+ + + EL K +
Sbjct: 387 AFDVKMENEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKR 446
Query: 538 ITQ--------LREFGAFDNLNDVGNM--------INQQRD-KLFELTKRQEEYDEKLQT 580
+ + + E NLN +NQ++D ++ EL K E+ D +
Sbjct: 447 LLEEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKE 506
Query: 581 KENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEE 615
++ + +E + ++NKKE I+ L E+ +
Sbjct: 507 TKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSK 541
Score = 33.9 bits (74), Expect = 2.0
Identities = 19/75 (25%), Positives = 40/75 (53%), Gaps = 1/75 (1%)
Query: 3 QEELE-IQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQ 61
QEELE +++ Q+ D +S+T + ++++L T+ + + +K +ED+
Sbjct: 581 QEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQS 640
Query: 62 VMELYASLRNTHRKM 76
M+L SL+ ++M
Sbjct: 641 KMQLLQSLQEQKKEM 655
Score = 31.9 bits (69), Expect = 8.0
Identities = 46/231 (19%), Positives = 101/231 (43%), Gaps = 16/231 (6%)
Query: 402 SIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHR 461
S+EE LQ+ + D +++ R+ L +E + + S+L+ + ++ST T
Sbjct: 127 SVEEVFRLQQALSDAENEIM----RLSSLNQE-ELQMSLLKLNN-EYEVIKSTATRDISL 180
Query: 462 KTEIEEYKRLLFEKGEEIDELKSKLSTEKA-IKDIXXXXXXXXXXXXXXXXXXXXXXXXR 520
+E+ + + L K +E+++ S+ T A I+++
Sbjct: 181 DSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEG 240
Query: 521 ESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQT 580
+S + ++L + K ++ QL D+ D+ ++ Q++KL + + Q
Sbjct: 241 DSIISKLKQDLNDEKKRVHQLE-----DDKMDITKELDVQKEKLIQSEVALNDLHLTKQK 295
Query: 581 KENEIKRLVESMTEQEH---VLNKKEKEIK-MLNEKEEEHMNIINLLHNKL 627
E++++ LV+ + + + + K+ E+K + + EEE I N L L
Sbjct: 296 LEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSL 346
>BC132736-1|AAI32737.1| 1843|Homo sapiens KIAA1212 protein.
Length = 1843
Score = 50.0 bits (114), Expect = 3e-05
Identities = 137/699 (19%), Positives = 269/699 (38%), Gaps = 55/699 (7%)
Query: 23 EQESITSESHKITKLKTVWQEKMVTF-----EKSKKELEDRQNQVMELYASLRNTHRKMK 77
EQE+ E KT+ K +TF EK +L++ ++ SL+ KM
Sbjct: 662 EQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMA 721
Query: 78 LLGQKVNLPSAEELHI---MNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLN 134
L + +E+ + + + K S ++ +L + +E+ L + K+
Sbjct: 722 QLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQ 781
Query: 135 IPNSLVD-KCE-ETLFKRKEIINW----FESLMSQEKGISTKT--LTMKIKEFNAENDLL 186
+ + L D + E +TL K E + E L + K + +T L K+ EN L
Sbjct: 782 LESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRL 841
Query: 187 KSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCA-LSDLNTQNAEMRKQIHS 245
+ + ++ L+E N I L K N+T++ ++ + SC L +L +N E+ K+
Sbjct: 842 RQQAE-IKDTTLEENNVKIGNLEKE-NKTLSKEIGIYKESCVRLKELEKENKELVKRATI 899
Query: 246 G---------DHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQL 296
D + K+RL E T+ R L
Sbjct: 900 DIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQS--TDDSRYKLL 957
Query: 297 EAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKL 356
E+ LE +S ++ +++Q+L + +++K N L+ +
Sbjct: 958 ESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMV 1017
Query: 357 QSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDL 416
QS + + ++ E+ +LIE+E+ EK+ L+ + L
Sbjct: 1018 QSSPPISGEDN-----KWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQL 1072
Query: 417 RTDLLESELRVKDLVRE---LDEKESILETK----QCVQKELESTKTDLEHRKTEIEEYK 469
T + ++ L R+ L E+ + L+T+ Q L S T L ++ ++ +
Sbjct: 1073 ETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQ 1132
Query: 470 RLLFEKGEEIDELKSKLST--EKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSY 527
L + E + + + L + + IKD +S K+
Sbjct: 1133 SSLENENESVIKEREDLKSLYDSLIKD-HEKLELLHERQASEYESLISKHGTLKSAHKNL 1191
Query: 528 YEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQE----EYDEKLQTKEN 583
E +L+++ QL + L D+ M+ +++K+ K E EY +KL + +
Sbjct: 1192 EVEHRDLEDRYNQLLK--QKGQLEDLEKMLKVEQEKMLLENKNHETVAAEY-KKLCGEND 1248
Query: 584 EIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIIT-LA 642
+ + ++ VL K +K L + + +KL+ + + +D+ T L
Sbjct: 1249 RLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQ-QLDITSTKLN 1307
Query: 643 KYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRT-LRKNM 680
+ L+ + + NR L + ++ Q+RT L +NM
Sbjct: 1308 NQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNM 1346
Score = 43.6 bits (98), Expect = 0.002
Identities = 90/480 (18%), Positives = 191/480 (39%), Gaps = 25/480 (5%)
Query: 187 KSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSG 246
K+ + +LR E ++ ++DC K E M ++L K L +L + R
Sbjct: 257 KAKIRRLRQELEEKTEQLLDC--KQELEQMEIEL--KRLQQENMNLLSDARSARMYRDEL 312
Query: 247 DHHRPYANR-NXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARS 305
D R A R + K R+ + + +E LE LE R+
Sbjct: 313 DALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRA 372
Query: 306 ES---WSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXX 362
S LE+ + D + K+ + +++N T LE +A + +S
Sbjct: 373 RSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMT-LE-MAQKQSMDESLHLG 430
Query: 363 XXXXXXXXSASYNKS-IKDMKHEMN-LNIAKLIEIE---KKYNDSIEEKKTLQENIDDLR 417
++ +++ K + HE+N L ++L+++E + ++EE +T ++++
Sbjct: 431 WELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNA 490
Query: 418 TDLLESELRVKDLVRELDEKES-ILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKG 476
+ +L+ E + L ++++ E+ I++ KQ +Q ++ DL K ++E+ L E
Sbjct: 491 SKILKMEKENQRLSKKVEILENEIVQEKQSLQ-NCQNLSKDLMKEKAQLEKTIETLRENS 549
Query: 477 EEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKN 536
E ++ + E + + +K +L ++
Sbjct: 550 ERQIKILEQ-ENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEF 608
Query: 537 QITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQE 596
+ Q+++ ++ + G + ++L L E+ +E LQ K +K E + E
Sbjct: 609 EKRQIKK--ELEHYKEKGERAEELENELHHL----EKENELLQKKITNLKITCEKIEALE 662
Query: 597 HVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMS 656
++ E+E + L + + N+ L + LE N + + L + +SL KM+
Sbjct: 663 QENSELERENRKLKKTLDSFKNLTFQLES-LEKENSQLDEENLELRRNVESLKCASMKMA 721
Score = 41.1 bits (92), Expect = 0.013
Identities = 122/662 (18%), Positives = 263/662 (39%), Gaps = 66/662 (9%)
Query: 1 MKQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQN 60
M +++LE + ++D L+E E + ++ H + + + ++K+ + LE Q
Sbjct: 362 MLEDQLEGTRARSDK-LHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQK 420
Query: 61 QVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEP--KALEH 118
Q M+ L ++ + P H +N +L+ +LL+L + K +E
Sbjct: 421 QSMDESLHLGWELEQISRTSELSEAPQKSLGHEVN--ELTSSRLLKLEMENQSLTKTVEE 478
Query: 119 --STLDNKVTFDVNKLLNIP------NSLVDKCEETLFKRKEII----NWFESLMSQ--- 163
+T+D+ V + +K+L + + V+ E + + K+ + N + LM +
Sbjct: 479 LRTTVDS-VEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQ 537
Query: 164 -EKGIST--KTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQL 220
EK I T + +IK EN+ L ++ LR + + K E L
Sbjct: 538 LEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEK---ENKILHE 594
Query: 221 RTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLS 280
KE S LS + + +++K++ +H++ R +++ +++
Sbjct: 595 SIKETSSKLSKIEFEKRQIKKEL---EHYKEKGER--AEELENELHHLEKENELLQKKIT 649
Query: 281 RAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXX---------XXXEDFDQE 331
LK E++ LE + E+ L++T+ ++ + E
Sbjct: 650 N----LKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLE 705
Query: 332 LNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKS-----------IKD 380
L + +S+K + + + L ++L+S AS+ K+ I++
Sbjct: 706 LRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIEN 765
Query: 381 MKHEMNLNIA--KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKE 438
+ + L + K+ ++E + D E +TLQ+N+++L+ E K+ + L+++
Sbjct: 766 QRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKE-NKSLEQET 824
Query: 439 SILE-TKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEK----AIK 493
S LE K+ ++KE + + E + T +EE + +E L ++ K +K
Sbjct: 825 SQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLK 884
Query: 494 DIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGA-FDNLND 552
++ S+ + +L+ +L + G + L
Sbjct: 885 ELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLH 944
Query: 553 VGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEK 612
+ R KL E +K + + L+ KE +I L + E + + +E+K + +
Sbjct: 945 DEQSTDDSRYKLLE-SKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKN 1003
Query: 613 EE 614
E
Sbjct: 1004 YE 1005
Score = 39.9 bits (89), Expect = 0.030
Identities = 62/296 (20%), Positives = 127/296 (42%), Gaps = 19/296 (6%)
Query: 375 NKSIKDMKHEMNLNIAKLIEIEKKYNDSIE-EKKTLQENIDDLRT-DLLESELRVKDLVR 432
+K + K ++ I L E ++ +E E + L + + LR + +E RVKD+ +
Sbjct: 528 SKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEK 587
Query: 433 ELDE-KESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
E ESI ET + K +E K + K E+E YK EKGE +EL+++L +
Sbjct: 588 ENKILHESIKETSSKLSK-IEFEKRQI---KKELEHYK----EKGERAEELENELHHLEK 639
Query: 492 IKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLN 551
++ E + + + L + KN QL ++
Sbjct: 640 ENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQL 699
Query: 552 DVGNM---INQQRDKLFELTKRQEEYDEK-LQTKENEIKRLVESMTEQEHVLNKKEKEIK 607
D N+ N + K + Q + + K L++++ ++K+ +E + + E +
Sbjct: 700 DEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQ 759
Query: 608 MLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVLK 663
L+ + + + + K++ + E+++ L ++L LE++ IS++ L+
Sbjct: 760 GLDIENQRLQKTLENSNKKIQ-QLESELQ---DLEMENQTLQKNLEELKISSKRLE 811
>BC034991-1|AAH34991.1| 495|Homo sapiens meiosis-specific nuclear
structural 1 protein.
Length = 495
Score = 50.0 bits (114), Expect = 3e-05
Identities = 67/312 (21%), Positives = 138/312 (44%), Gaps = 38/312 (12%)
Query: 333 NKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKL 392
N++ Q+ DN + LQ+ A NK +K+++ + +A
Sbjct: 40 NQMVQNENDNRVQRKQFL---RLLQNEQFELDMEEAIQKAEENKRLKELQLKQEEKLA-- 94
Query: 393 IEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELE 452
+E+ K ++S++++K +++ + + +L E E ++K + I E K ++ E
Sbjct: 95 MELAKLKHESLKDEK-MRQQVRENSIELRELEKKLKAAYMNKERAAQIAE-KDAIK--YE 150
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXX 512
K D E KT +EE+KR++ E+ D+ ++K + + D+
Sbjct: 151 QMKRDAEIAKTMMEEHKRIIKEENAAEDK-RNKAKAQYYL-DLEKQLEE----------- 197
Query: 513 XXXXXXXRESQMKSYYEELMNLKNQITQL-REFGAFDNLNDVGNM--INQQRDKLFELTK 569
+E + + YE+L+ K I ++ R+ D L + +N R + E K
Sbjct: 198 -------QEKKKQEAYEQLLKEKLMIDEIVRKIYEEDQLEKQQKLEKMNAMRRYIEEFQK 250
Query: 570 RQEEYDEKLQTK-ENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
Q + +K + + E E ++++E Q+ ++E + + E EE+ + + N L KLE
Sbjct: 251 EQALWRKKKREEMEEENRKIIEFANMQQQ---REEDRMAKVQENEEKRLQLQNALTQKLE 307
Query: 629 --LRNEADIDVI 638
LR D++ +
Sbjct: 308 EMLRQREDLEQV 319
>AY703984-1|AAV80770.1| 1581|Homo sapiens SP-A receptor subunit
SP-R210 alphaS protein.
Length = 1581
Score = 50.0 bits (114), Expect = 3e-05
Identities = 58/346 (16%), Positives = 147/346 (42%), Gaps = 17/346 (4%)
Query: 275 MKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNK 334
+K +L + + ++VV LEA L+ S+ E ++ D + ++
Sbjct: 1040 LKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQL----RDLEAKVKD 1095
Query: 335 LTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKL-I 393
+ + + ++ + A+ +L+ S ++ +++ + + ++ +
Sbjct: 1096 QEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEV 1155
Query: 394 EIEKKYNDS---IEEKKTLQENIDDLRTDLLESELRV-KDLVRELDEKESILETKQCVQK 449
++E++Y D + EK+ L+ + L + + K L ++L +++L Q +
Sbjct: 1156 QLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLD 1215
Query: 450 ELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE-LKSKLSTEKAIKDIXXXXXXXXXXXXX 508
L+++ K EI + K L E +K++ + E I+D+
Sbjct: 1216 HLKNSAPS----KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTA 1271
Query: 509 XXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELT 568
+ +++++ EE N++ + + D+ IN + +L E
Sbjct: 1272 LEEQLSRLQREK-NEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQ-INDLQAQLEEAN 1329
Query: 569 KRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEE 614
K ++E EKLQ +++++ L +SM ++ +++++E +I+ L + E
Sbjct: 1330 KEKQELQEKLQALQSQVEFLEQSMVDKS-LVSRQEAKIRELETRLE 1374
Score = 35.9 bits (79), Expect = 0.49
Identities = 45/263 (17%), Positives = 106/263 (40%), Gaps = 14/263 (5%)
Query: 394 EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELES 453
E E K + K+ L+ + DL+ D ES+ ++ L ++ Q + EL+
Sbjct: 934 EFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC----------QRLTAELQD 983
Query: 454 TKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXX 513
TK LE ++ E ++ E+ + + EK ++
Sbjct: 984 TKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQRE---KLQREKDMLLAEAFSL 1040
Query: 514 XXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEE 573
++ + + +++++L+ ++ + + D + + + Q RD ++ ++EE
Sbjct: 1041 KQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEAS-LAKVKKQLRDLEAKVKDQEEE 1099
Query: 574 YDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEA 633
DE+ T + + + E E + KE++ +E+ EE ++E++ E
Sbjct: 1100 LDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1159
Query: 634 DIDVIITLAKYKKSLTLVLEKMS 656
+ + + + K+ L L +S
Sbjct: 1160 EYEDKQKVLREKRELEGKLATLS 1182
Score = 35.5 bits (78), Expect = 0.65
Identities = 44/235 (18%), Positives = 94/235 (40%), Gaps = 20/235 (8%)
Query: 378 IKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEK 437
+K+ E A ++ K IE+ L IDD+ E ++ L RE +E
Sbjct: 1230 LKNQLEESEFTCAAAVKARKAMEVEIED---LHLQIDDIAKAKTALEEQLSRLQREKNEI 1286
Query: 438 ESILETKQCVQKEL----ESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIK 493
++ LE Q EL ++ +I + + L E +E EL+ KL ++
Sbjct: 1287 QNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQV 1346
Query: 494 DIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDV 553
+ +E++++ L + Q+ +L + L +
Sbjct: 1347 EFLEQSMVDKSLVSR-----------QEAKIRELETRLEFERTQVKRLESLAS--RLKEN 1393
Query: 554 GNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM 608
+ ++RD+ R++E +++LQ + + K + + +E ++K+ E++M
Sbjct: 1394 MEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEM 1448
>AY651261-1|AAX35689.1| 1244|Homo sapiens centrosomal protein 1
protein.
Length = 1244
Score = 50.0 bits (114), Expect = 3e-05
Identities = 58/247 (23%), Positives = 116/247 (46%), Gaps = 16/247 (6%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEE-KKTLQENIDDLRTDLLESELRVKDL 430
AS +S K+M+ E++ NI L++ +K +EE +T+Q+ + D ++ V+ L
Sbjct: 914 ASKRQSEKEME-ELHHNIDDLLQEKKSLECEVEELHRTVQKR--QQQKDFIDGN--VESL 968
Query: 431 VRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEK 490
+ EL+ ++S+ + V E+E + L R++E+ E RLL E E+ K K T+
Sbjct: 969 MTELEIEKSLKHHEDIVD-EIECIEKTLLKRRSELREADRLLAEAESELSCTKEK--TKN 1025
Query: 491 AIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLRE--FGAFD 548
A++ + +K+ ++L +L+ L + +
Sbjct: 1026 AVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKA-DQQLRSLQADAKDLEQHKIKQEE 1084
Query: 549 NLNDVGNMINQQRDKLFE-LTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK 607
L ++ N I +D F+ L+K++E+ E+LQ + +I+ + E H+ KE E+
Sbjct: 1085 ILKEI-NKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIE--MAERNEDHHLQVLKESEVL 1141
Query: 608 MLNEKEE 614
+ ++ E
Sbjct: 1142 LQAKRAE 1148
Score = 39.5 bits (88), Expect = 0.040
Identities = 34/144 (23%), Positives = 71/144 (49%), Gaps = 3/144 (2%)
Query: 529 EELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRL 588
EE + LK +I++ + + L+ ++N+ R + +L + E+ +++ K+ EIK L
Sbjct: 45 EEAIQLK-KISEAGKDLLYKQLSGRLQLVNKLRQEALDLELQMEKQKQEIAGKQKEIKDL 103
Query: 589 VESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSL 648
++ + + K +K +E+ ++I+N + +LE R + + I + K L
Sbjct: 104 QIAIDSLDS-KDPKHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDL 162
Query: 649 TLVLEKMSI-SNRVLKCSLLGVVT 671
L + I +N LK L GV++
Sbjct: 163 EEQLTEGQIAANEALKKDLEGVIS 186
Score = 37.1 bits (82), Expect = 0.21
Identities = 45/209 (21%), Positives = 80/209 (38%), Gaps = 11/209 (5%)
Query: 290 VERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDI 349
V+ + +E L + RSE +R + E + K T + K + E
Sbjct: 985 VDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDA-KRSLLQTESD 1043
Query: 350 ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH------EMNLNIAKLIEIEKKYNDSI 403
A E+ S KD++ E+ I K++ + +
Sbjct: 1044 AEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCL 1103
Query: 404 EEKKT-LQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRK 462
+KK L E + L+ D+ +E ++ L E E +L+ K+ ELE K+ + ++
Sbjct: 1104 SKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRA---ELEKLKSQVTSQQ 1160
Query: 463 TEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
E+ R L K EE+ L+ + KA
Sbjct: 1161 QEMAVLDRQLGHKKEELHLLQGSMVQAKA 1189
Score = 36.7 bits (81), Expect = 0.28
Identities = 52/238 (21%), Positives = 100/238 (42%), Gaps = 32/238 (13%)
Query: 276 KDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKL 335
+ LS + + K VE+ + +L Q S++ LER DQ+L L
Sbjct: 1013 ESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKA----DQQLRSL 1068
Query: 336 TQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEI 395
KD LE + +E++ +K + + E+ + K IE+
Sbjct: 1069 QADAKD----LEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQ-KLQKDIEM 1123
Query: 396 EKKYNDS----IEEKKTL----QENIDDLRTDLLESELRVKDLVRELDEKE--------S 439
++ D ++E + L + ++ L++ + + + L R+L K+ S
Sbjct: 1124 AERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGS 1183
Query: 440 ILETKQCVQKELESTKTDLEHRKTEIEEYKRLL----FEKGE---EIDELKSKLSTEK 490
+++ K +Q+ L +T++ + I E K LL F+KGE +I E K++L+ K
Sbjct: 1184 MVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIK 1241
Score = 36.3 bits (80), Expect = 0.37
Identities = 69/348 (19%), Positives = 133/348 (38%), Gaps = 24/348 (6%)
Query: 273 SIMKDRLSRAEHQLKTNVERVVQLEAALEQAR-SESWS--LERTVXXXXXXXXXXXE--- 326
S + D + +AE Q+ E QLE A++ + SE+ L + + +
Sbjct: 21 SELHDEIEKAEQQILRATEEFKQLEEAIQLKKISEAGKDLLYKQLSGRLQLVNKLRQEAL 80
Query: 327 DFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMN 386
D + ++ K Q I ++D+ +A + L S S + + M +
Sbjct: 81 DLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSGK-EQQLDIMNKQYQ 139
Query: 387 LNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILET--K 444
++L EI + EE K L+E + + + +E KDL + + L T
Sbjct: 140 QLESRLDEILSRIAKETEEIKDLEEQLTE--GQIAANEALKKDLEGVISGLQEYLGTIKG 197
Query: 445 QCVQ-----KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS-TEKAIK---DI 495
Q Q ++L K L R TE+E+ + L + + ++ +L+ E A++ ++
Sbjct: 198 QATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEV 257
Query: 496 XXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGN 555
R+++ EEL + ++TQL + L
Sbjct: 258 NASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKV-TRLTQLEQSALQAELEKERQ 316
Query: 556 MINQQRDKL-FELTKRQE--EYDEKLQTKENEIKRLVESMTEQEHVLN 600
+ K F K QE E KL+ +++ L + + + ++ LN
Sbjct: 317 ALKNALGKAQFSEEKEQENSELHAKLKHLQDDNNLLKQQLKDFQNHLN 364
>AL596220-1|CAI13119.1| 2363|Homo sapiens translocated promoter region
(to activated MET oncogene) protein.
Length = 2363
Score = 50.0 bits (114), Expect = 3e-05
Identities = 60/270 (22%), Positives = 114/270 (42%), Gaps = 34/270 (12%)
Query: 394 EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESI-LETKQCV---QK 449
+IEK ++ KK L+ ++ T ++++ D R+LD + ++ L TK+ + QK
Sbjct: 840 QIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQK 899
Query: 450 ELESTKTDLEHRKTEIEEYKRLLFEKG-----EEIDELKSKL-STEKAIKDIXXXXXXXX 503
E+ + K L + + ++ KG E++D+L S+L TE+ + D+
Sbjct: 900 EIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDL-------- 951
Query: 504 XXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDK 563
+ M + EE +N + Q+T+ L + Q K
Sbjct: 952 ----KERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKK 1007
Query: 564 LFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLL 623
L E+ K ++E +++ +R +ESM +Q L K ++ NE +E L
Sbjct: 1008 LMEVEKEKQEL-------QDDKRRAIESMEQQLSELKKTLSSVQ--NEVQEALQRASTAL 1058
Query: 624 HNKLELRNEADIDVIITLA---KYKKSLTL 650
N+ + R + I + KY++ L L
Sbjct: 1059 SNEQQARRDCQEQAKIAVEAQNKYERELML 1088
Score = 42.7 bits (96), Expect = 0.004
Identities = 58/291 (19%), Positives = 122/291 (41%), Gaps = 23/291 (7%)
Query: 331 ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIA 390
EL KL +K T +++ +A+++ + A I+ ++ +
Sbjct: 81 ELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRT-NERLSQELE 139
Query: 391 KLIEIEKKYNDSIEEKKT----LQENIDDLRTDLLESELRVKDLVRELDEKESILETKQC 446
L E K+ N+ ++E T LQ +D+L+ S++ VK + L++++ +L ++
Sbjct: 140 YLTEDVKRLNEKLKESNTTKGELQLKLDELQA----SDVSVKYREKRLEQEKELLHSQNT 195
Query: 447 VQKELESTKTD----LEHRK-TEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXX 501
TKTD L K EI E K L K EE+ L+ +++ K +
Sbjct: 196 WLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNE------- 248
Query: 502 XXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQR 561
+++ M+ + +N +++ L + A D+ N + +
Sbjct: 249 HLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYK-SAADDSEAKSNELTRAV 307
Query: 562 DKLFELTKRQEEYDEKLQTKENEIKRLVESM-TEQEHVLNKKEKEIKMLNE 611
++L +L K E ++ +Q E+++ + M E + + EKE++ N+
Sbjct: 308 EELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMLEKIGRLEKELENAND 358
Score = 41.5 bits (93), Expect = 0.010
Identities = 119/666 (17%), Positives = 262/666 (39%), Gaps = 59/666 (8%)
Query: 2 KQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFE------KSKKEL 55
+Q E + + + L +L + I S TK + Q + + E K + E+
Sbjct: 800 QQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEV 859
Query: 56 EDRQNQVMELYASLRNTHRKMKL-----LGQKVNLPSAEE------LHIMNVAKLSPEQL 104
E R L L +T R++ L K L +A++ H+ N+ Q
Sbjct: 860 EQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQS 919
Query: 105 LQLCAGGEPKALEHSTLDNKVTF--DVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMS 162
Q G+P E +D+ V+ + +N + + + + ++ E ++
Sbjct: 920 SQRTGKGQPSNKED--VDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLN 977
Query: 163 QEKGIST---KTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQ 219
+EK ++ K + +++KE +AE ++ L++ E KE ++ D R+ A E+M Q
Sbjct: 978 KEKQVTEEVRKNIEVRLKE-SAE---FQTQLEKKLMEVEKEKQELQDDKRR-AIESMEQQ 1032
Query: 220 LRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRL 279
L EL LS + + E ++ + + A R+ +
Sbjct: 1033 L--SELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHA 1090
Query: 280 SRAE--HQLKTNVERVVQLEAALEQA--RSESWSLERTVXXXXXXXXXXXEDFD-----Q 330
+ E K V ++ + LE+ ++ES LE E +
Sbjct: 1091 ADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCE 1150
Query: 331 ELNKLTQSIKDNTTHLED--IALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLN 388
+L K + + D L D +A +E +Q + ++ ++ E +
Sbjct: 1151 DLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIA 1210
Query: 389 IAK--LIEIEK-KYNDSIEE-KKTLQENIDDLRTDLLESELRVK------DLVRELDEKE 438
+ + ++E +Y +E ++ LQE D L + + ++ K +L+++ +
Sbjct: 1211 ETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMN 1270
Query: 439 SILETKQCVQKELESTKTDLEHRKTEIEEYK---RLLFEKGEEIDELKSKLSTEKAI--K 493
++ET + +++E E + DL+ + ++ + + L E E+ E L EK + +
Sbjct: 1271 VVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEE 1330
Query: 494 DIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDN--LN 551
D+ S+ + + + + L +I +L+ A N L
Sbjct: 1331 DVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLT 1390
Query: 552 DVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNE 611
+ N+I ++ L ++ +E + L K +I+ V+++T+ + + + + + + L
Sbjct: 1391 NNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKA 1450
Query: 612 KEEEHM 617
++++ M
Sbjct: 1451 QQDKVM 1456
Score = 35.9 bits (79), Expect = 0.49
Identities = 49/263 (18%), Positives = 108/263 (41%), Gaps = 14/263 (5%)
Query: 401 DSIEEK---KTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQC-VQKELESTKT 456
++IE K K LQE ++ + + E+E + + +L E+ + L ++ + +L+
Sbjct: 664 EAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASK 723
Query: 457 DLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXX 516
E + +E Y+R + E +L + ++ I +
Sbjct: 724 RYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIIN-TMTQDLRGANEKLAVAEVRAE 782
Query: 517 XXXRESQMKSYYEELMNLKNQITQLREFGA---FDNLNDVGNMINQQRDKLFELTKRQEE 573
+E +M E ++ + + + G NL + ++ + E +R
Sbjct: 783 NLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSET---ETKQRLSS 839
Query: 574 YDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEA 633
EKL+ + + +K+ +E+ EQ H L + ++++L+ K + NL N EL A
Sbjct: 840 QIEKLEHEISHLKKKLENEVEQRHTLT-RNLDVQLLDTKRQLDTE-TNLHLNTKELLKNA 897
Query: 634 DIDVIITLAKYKKSLTLVLEKMS 656
+ I TL ++ ++ + + S
Sbjct: 898 QKE-IATLKQHLSNMEVQVASQS 919
Score = 34.7 bits (76), Expect = 1.1
Identities = 48/252 (19%), Positives = 105/252 (41%), Gaps = 11/252 (4%)
Query: 379 KDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKE 438
K+++ + NIA + + + EK+ L + L +L VK L +L E
Sbjct: 97 KELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESN 156
Query: 439 SILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEID-ELKSKLSTEKAIKDIXX 497
+ Q EL+++ +++R+ +E+ K LL + ++ ELK+K A+
Sbjct: 157 TTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKG 216
Query: 498 XXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELM-NLKNQITQLREFGAFDNLNDVGNM 556
+ + +K+ E L ++++ +T+L+E A + +
Sbjct: 217 NEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKE--AKEQQASMEEK 274
Query: 557 INQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEH 616
+ + + +L+ + + + K NE+ R VE L+K KE N+ ++H
Sbjct: 275 FHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEE-------LHKLLKEAGEANKAIQDH 327
Query: 617 MNIINLLHNKLE 628
+ + +++E
Sbjct: 328 LLEVEQSKDQME 339
Score = 32.3 bits (70), Expect = 6.1
Identities = 39/167 (23%), Positives = 74/167 (44%), Gaps = 17/167 (10%)
Query: 57 DRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKAL 116
++ N+++EL +L N ++ L +++N H+ K + L +L E +A
Sbjct: 214 EKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQ---KHVEDLLTKLKEAKEQQAS 270
Query: 117 EHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESL--MSQEKGISTKTLTM 174
N++ + KL N+ S D E K E+ E L + +E G + K +
Sbjct: 271 MEEKFHNELNAHI-KLSNLYKSAADDSEA---KSNELTRAVEELHKLLKEAGEANKAIQD 326
Query: 175 KIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLR 221
+ E ++ S DQ+ E L++I + L +NAN+ ++ R
Sbjct: 327 HLLE-------VEQSKDQMEKEMLEKIGRLEKEL-ENANDLLSATKR 365
>AL137068-6|CAI12359.1| 346|Homo sapiens centrosomal protein 110kDa
protein.
Length = 346
Score = 50.0 bits (114), Expect = 3e-05
Identities = 58/247 (23%), Positives = 116/247 (46%), Gaps = 16/247 (6%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEE-KKTLQENIDDLRTDLLESELRVKDL 430
AS +S K+M+ E++ NI L++ +K +EE +T+Q+ + D ++ V+ L
Sbjct: 16 ASKRQSEKEME-ELHHNIDDLLQEKKSLECEVEELHRTVQKR--QQQKDFIDGN--VESL 70
Query: 431 VRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEK 490
+ EL+ ++S+ + V E+E + L R++E+ E RLL E E+ K K T+
Sbjct: 71 MTELEIEKSLKHHEDIVD-EIECIEKTLLKRRSELREADRLLAEAESELSCTKEK--TKN 127
Query: 491 AIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLRE--FGAFD 548
A++ + +K+ ++L +L+ L + +
Sbjct: 128 AVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKA-DQQLRSLQADAKDLEQHKIKQEE 186
Query: 549 NLNDVGNMINQQRDKLFE-LTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK 607
L ++ N I +D F+ L+K++E+ E+LQ + +I+ + E H+ KE E+
Sbjct: 187 ILKEI-NKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIE--MAERNEDHHLQVLKESEVL 243
Query: 608 MLNEKEE 614
+ ++ E
Sbjct: 244 LQAKRAE 250
Score = 37.1 bits (82), Expect = 0.21
Identities = 45/209 (21%), Positives = 80/209 (38%), Gaps = 11/209 (5%)
Query: 290 VERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDI 349
V+ + +E L + RSE +R + E + K T + K + E
Sbjct: 87 VDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDA-KRSLLQTESD 145
Query: 350 ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH------EMNLNIAKLIEIEKKYNDSI 403
A E+ S KD++ E+ I K++ + +
Sbjct: 146 AEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCL 205
Query: 404 EEKKT-LQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRK 462
+KK L E + L+ D+ +E ++ L E E +L+ K+ ELE K+ + ++
Sbjct: 206 SKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRA---ELEKLKSQVTSQQ 262
Query: 463 TEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
E+ R L K EE+ L+ + KA
Sbjct: 263 QEMAVLDRQLGHKKEELHLLQGSMVQAKA 291
Score = 36.7 bits (81), Expect = 0.28
Identities = 52/238 (21%), Positives = 100/238 (42%), Gaps = 32/238 (13%)
Query: 276 KDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKL 335
+ LS + + K VE+ + +L Q S++ LER DQ+L L
Sbjct: 115 ESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKA----DQQLRSL 170
Query: 336 TQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEI 395
KD LE + +E++ +K + + E+ + K IE+
Sbjct: 171 QADAKD----LEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQ-KLQKDIEM 225
Query: 396 EKKYNDS----IEEKKTL----QENIDDLRTDLLESELRVKDLVRELDEKE--------S 439
++ D ++E + L + ++ L++ + + + L R+L K+ S
Sbjct: 226 AERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGS 285
Query: 440 ILETKQCVQKELESTKTDLEHRKTEIEEYKRLL----FEKGE---EIDELKSKLSTEK 490
+++ K +Q+ L +T++ + I E K LL F+KGE +I E K++L+ K
Sbjct: 286 MVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIK 343
>AL137068-5|CAI12358.1| 1773|Homo sapiens centrosomal protein 110kDa
protein.
Length = 1773
Score = 50.0 bits (114), Expect = 3e-05
Identities = 58/247 (23%), Positives = 116/247 (46%), Gaps = 16/247 (6%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEE-KKTLQENIDDLRTDLLESELRVKDL 430
AS +S K+M+ E++ NI L++ +K +EE +T+Q+ + D ++ V+ L
Sbjct: 795 ASKRQSEKEME-ELHHNIDDLLQEKKSLECEVEELHRTVQKR--QQQKDFIDGN--VESL 849
Query: 431 VRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEK 490
+ EL+ ++S+ + V E+E + L R++E+ E RLL E E+ K K T+
Sbjct: 850 MTELEIEKSLKHHEDIVD-EIECIEKTLLKRRSELREADRLLAEAESELSCTKEK--TKN 906
Query: 491 AIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLRE--FGAFD 548
A++ + +K+ ++L +L+ L + +
Sbjct: 907 AVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKA-DQQLRSLQADAKDLEQHKIKQEE 965
Query: 549 NLNDVGNMINQQRDKLFE-LTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK 607
L ++ N I +D F+ L+K++E+ E+LQ + +I+ + E H+ KE E+
Sbjct: 966 ILKEI-NKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIE--MAERNEDHHLQVLKESEVL 1022
Query: 608 MLNEKEE 614
+ ++ E
Sbjct: 1023 LQAKRAE 1029
Score = 43.6 bits (98), Expect = 0.002
Identities = 90/506 (17%), Positives = 210/506 (41%), Gaps = 42/506 (8%)
Query: 2 KQEELEIQQN---QTDGCLYEDLNEQES-ITSESHKITKLKTVWQEKMVTFEKSKK--EL 55
K+EEL + Q Q L E L E+ +T + + I ++K++ +E ++F+K + ++
Sbjct: 1054 KKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEE--LSFQKGELNVQI 1111
Query: 56 EDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKA 115
+R+ Q+ + + ++++ ++++ E +I+++ +L +L L + +
Sbjct: 1112 SERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRV 1171
Query: 116 LEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMK 175
E L+ + + L + N ++ ++K I W + L+ ++K +
Sbjct: 1172 SE---LEKTQVAVLEEKLELEN-----LQQISQQQKGEIEWQKQLLERDK--------RE 1215
Query: 176 IKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELS-CALSDLNT 234
I+ AE+ L+S ++ L E +++ + D K +T + +E S S+L
Sbjct: 1216 IERMTAESRALQSCVECLSKE-KEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEK 1274
Query: 235 QNAEMRKQIHSGD--HHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVER 292
+RK D + + N + +++ L+ + L +
Sbjct: 1275 LELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQD 1334
Query: 293 VVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFD---QELNKLTQSIKDNTTHLEDI 349
++ + SE L++ + ++ + Q+L L I++N L
Sbjct: 1335 LLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQ 1394
Query: 350 ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTL 409
+ ++LQ + + ++ E+ +KL ++ K + E +TL
Sbjct: 1395 EMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTL 1454
Query: 410 QEN---IDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTE-I 465
QE + L L +++ ++ + ++L EK L +QKE +S + D + + +
Sbjct: 1455 QEEERWCESLEKTLSQTKRQLSEREQQLVEKSGEL---LALQKEADSMRADFSLLRNQFL 1511
Query: 466 EEYKRLLFEKGEEIDELKSKLSTEKA 491
E K+ EK ++ LK L +++
Sbjct: 1512 TERKKA--EK--QVASLKEALKIQRS 1533
Score = 43.2 bits (97), Expect = 0.003
Identities = 77/465 (16%), Positives = 187/465 (40%), Gaps = 25/465 (5%)
Query: 25 ESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVN 84
E ++ E + + +W++K+ ++ E+ N ME ++L ++ L Q+++
Sbjct: 1231 ECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEE--NSKME-QSNLEKLELNVRKLQQELD 1287
Query: 85 LPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCE 144
+ ++L + N +QL + E + + + + LL+
Sbjct: 1288 QLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLS 1347
Query: 145 ETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDI 204
E +K+I W +K TK +++ + E + LK ++ + L++ +
Sbjct: 1348 EQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERES 1407
Query: 205 IDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXX 264
+ + + T+ Q +L L+D ++ ++ ++ + +
Sbjct: 1408 EESKLETSKVTLKEQQH--QLEKELTDQKSKLDQVLSKVLAAEER------------VRT 1453
Query: 265 XXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXX 324
++ LS+ + QL +++V+ L + E+ S+
Sbjct: 1454 LQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTE 1513
Query: 325 XEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHE 384
+ ++++ L +++K + LE L +++ S + ++ + + E
Sbjct: 1514 RKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQDNHERARRLMKE 1573
Query: 385 MNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRT--DLLESELR--VKDLVRELDE---- 436
+N + E++K+ + + ++ E D +RT ++ E+R +K+L + L E
Sbjct: 1574 LNQMQYEYTELKKQMANQKDLERRQMEISDAMRTLKSEVKDEIRTSLKNLNQFLPELPAD 1633
Query: 437 KESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE 481
E+ILE + ++ ELES K +L E ++L F + +DE
Sbjct: 1634 LEAILERNENLEGELESLKENLPFTMNEGPFEEKLNFSQVHIMDE 1678
Score = 37.1 bits (82), Expect = 0.21
Identities = 45/209 (21%), Positives = 80/209 (38%), Gaps = 11/209 (5%)
Query: 290 VERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDI 349
V+ + +E L + RSE +R + E + K T + K + E
Sbjct: 866 VDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDA-KRSLLQTESD 924
Query: 350 ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH------EMNLNIAKLIEIEKKYNDSI 403
A E+ S KD++ E+ I K++ + +
Sbjct: 925 AEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCL 984
Query: 404 EEKKT-LQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRK 462
+KK L E + L+ D+ +E ++ L E E +L+ K+ ELE K+ + ++
Sbjct: 985 SKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRA---ELEKLKSQVTSQQ 1041
Query: 463 TEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
E+ R L K EE+ L+ + KA
Sbjct: 1042 QEMAVLDRQLGHKKEELHLLQGSMVQAKA 1070
Score = 36.7 bits (81), Expect = 0.28
Identities = 52/238 (21%), Positives = 100/238 (42%), Gaps = 32/238 (13%)
Query: 276 KDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKL 335
+ LS + + K VE+ + +L Q S++ LER DQ+L L
Sbjct: 894 ESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKA----DQQLRSL 949
Query: 336 TQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEI 395
KD LE + +E++ +K + + E+ + K IE+
Sbjct: 950 QADAKD----LEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQ-KLQKDIEM 1004
Query: 396 EKKYNDS----IEEKKTL----QENIDDLRTDLLESELRVKDLVRELDEKE--------S 439
++ D ++E + L + ++ L++ + + + L R+L K+ S
Sbjct: 1005 AERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGS 1064
Query: 440 ILETKQCVQKELESTKTDLEHRKTEIEEYKRLL----FEKGE---EIDELKSKLSTEK 490
+++ K +Q+ L +T++ + I E K LL F+KGE +I E K++L+ K
Sbjct: 1065 MVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIK 1122
Score = 33.5 bits (73), Expect = 2.6
Identities = 24/86 (27%), Positives = 45/86 (52%), Gaps = 6/86 (6%)
Query: 404 EEKKTLQENIDDLRTDLLESELRVKD---LVRELDEKESILETKQCVQKELESTKTDLEH 460
+EK+TL + + ++ + + E+ D + +EL E ES L+ + V L+ T+ DL
Sbjct: 92 DEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEVNASLQQTQGDLSA 151
Query: 461 RKTEIEEYKRLLFEKGEEIDELKSKL 486
+ E+E L + E ++LK +L
Sbjct: 152 YEAELEARLNL---RDAEANQLKEEL 174
Score = 31.9 bits (69), Expect = 8.0
Identities = 71/372 (19%), Positives = 143/372 (38%), Gaps = 23/372 (6%)
Query: 275 MKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNK 334
+++ L E ++ + ++++ LE+ + L + ++ ++E
Sbjct: 1072 LQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEEN 1131
Query: 335 LTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH--EMNLNIAKL 392
L ++ + H ++ + LQ ++ K E L + L
Sbjct: 1132 LQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENL 1191
Query: 393 IEIEKKYNDSIEEKKTLQENIDDLRTDLLESELR-VKDLVRELD-EKESILETKQCVQKE 450
+I ++ IE +K L E D + + +E R ++ V L EKE + E +K+
Sbjct: 1192 QQISQQQKGEIEWQKQLLER-DKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKK 1250
Query: 451 LESTKTDL----EHRKTEIEEYKRL---LFEKGEEIDEL-KSKLSTEKAIKDIXXXXXXX 502
L TK L E+ K E ++L + + +E+D+L + KLS DI
Sbjct: 1251 LAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHN---DISAMQQQL 1307
Query: 503 XXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRD 562
++ + + L K+Q L E D+ N+ D
Sbjct: 1308 QEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQK--DISEWANRFED 1365
Query: 563 -KLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM----LNEKEEEHM 617
+ E TK+Q+ + + +EN++K + + M Q ++ +E K+ + KE++H
Sbjct: 1366 CQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQ 1425
Query: 618 NIINLLHNKLEL 629
L K +L
Sbjct: 1426 LEKELTDQKSKL 1437
>AL137068-2|CAM13285.1| 2325|Homo sapiens centrosomal protein 110kDa
protein.
Length = 2325
Score = 50.0 bits (114), Expect = 3e-05
Identities = 58/247 (23%), Positives = 116/247 (46%), Gaps = 16/247 (6%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEE-KKTLQENIDDLRTDLLESELRVKDL 430
AS +S K+M+ E++ NI L++ +K +EE +T+Q+ + D ++ V+ L
Sbjct: 1347 ASKRQSEKEME-ELHHNIDDLLQEKKSLECEVEELHRTVQKR--QQQKDFIDGN--VESL 1401
Query: 431 VRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEK 490
+ EL+ ++S+ + V E+E + L R++E+ E RLL E E+ K K T+
Sbjct: 1402 MTELEIEKSLKHHEDIVD-EIECIEKTLLKRRSELREADRLLAEAESELSCTKEK--TKN 1458
Query: 491 AIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLRE--FGAFD 548
A++ + +K+ ++L +L+ L + +
Sbjct: 1459 AVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKA-DQQLRSLQADAKDLEQHKIKQEE 1517
Query: 549 NLNDVGNMINQQRDKLFE-LTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK 607
L ++ N I +D F+ L+K++E+ E+LQ + +I+ + E H+ KE E+
Sbjct: 1518 ILKEI-NKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIE--MAERNEDHHLQVLKESEVL 1574
Query: 608 MLNEKEE 614
+ ++ E
Sbjct: 1575 LQAKRAE 1581
Score = 43.6 bits (98), Expect = 0.002
Identities = 90/506 (17%), Positives = 210/506 (41%), Gaps = 42/506 (8%)
Query: 2 KQEELEIQQN---QTDGCLYEDLNEQES-ITSESHKITKLKTVWQEKMVTFEKSKK--EL 55
K+EEL + Q Q L E L E+ +T + + I ++K++ +E ++F+K + ++
Sbjct: 1606 KKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEE--LSFQKGELNVQI 1663
Query: 56 EDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKA 115
+R+ Q+ + + ++++ ++++ E +I+++ +L +L L + +
Sbjct: 1664 SERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRV 1723
Query: 116 LEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMK 175
E L+ + + L + N ++ ++K I W + L+ ++K +
Sbjct: 1724 SE---LEKTQVAVLEEKLELEN-----LQQISQQQKGEIEWQKQLLERDK--------RE 1767
Query: 176 IKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELS-CALSDLNT 234
I+ AE+ L+S ++ L E +++ + D K +T + +E S S+L
Sbjct: 1768 IERMTAESRALQSCVECLSKE-KEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEK 1826
Query: 235 QNAEMRKQIHSGD--HHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVER 292
+RK D + + N + +++ L+ + L +
Sbjct: 1827 LELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQD 1886
Query: 293 VVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFD---QELNKLTQSIKDNTTHLEDI 349
++ + SE L++ + ++ + Q+L L I++N L
Sbjct: 1887 LLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQ 1946
Query: 350 ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTL 409
+ ++LQ + + ++ E+ +KL ++ K + E +TL
Sbjct: 1947 EMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTL 2006
Query: 410 QEN---IDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTE-I 465
QE + L L +++ ++ + ++L EK L +QKE +S + D + + +
Sbjct: 2007 QEEERWCESLEKTLSQTKRQLSEREQQLVEKSGEL---LALQKEADSMRADFSLLRNQFL 2063
Query: 466 EEYKRLLFEKGEEIDELKSKLSTEKA 491
E K+ EK ++ LK L +++
Sbjct: 2064 TERKKA--EK--QVASLKEALKIQRS 2085
Score = 43.2 bits (97), Expect = 0.003
Identities = 77/465 (16%), Positives = 187/465 (40%), Gaps = 25/465 (5%)
Query: 25 ESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVN 84
E ++ E + + +W++K+ ++ E+ N ME ++L ++ L Q+++
Sbjct: 1783 ECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEE--NSKME-QSNLEKLELNVRKLQQELD 1839
Query: 85 LPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCE 144
+ ++L + N +QL + E + + + + LL+
Sbjct: 1840 QLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLS 1899
Query: 145 ETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDI 204
E +K+I W +K TK +++ + E + LK ++ + L++ +
Sbjct: 1900 EQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERES 1959
Query: 205 IDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXX 264
+ + + T+ Q +L L+D ++ ++ ++ + +
Sbjct: 1960 EESKLETSKVTLKEQQH--QLEKELTDQKSKLDQVLSKVLAAEER------------VRT 2005
Query: 265 XXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXX 324
++ LS+ + QL +++V+ L + E+ S+
Sbjct: 2006 LQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTE 2065
Query: 325 XEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHE 384
+ ++++ L +++K + LE L +++ S + ++ + + E
Sbjct: 2066 RKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQDNHERARRLMKE 2125
Query: 385 MNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRT--DLLESELR--VKDLVRELDE---- 436
+N + E++K+ + + ++ E D +RT ++ E+R +K+L + L E
Sbjct: 2126 LNQMQYEYTELKKQMANQKDLERRQMEISDAMRTLKSEVKDEIRTSLKNLNQFLPELPAD 2185
Query: 437 KESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE 481
E+ILE + ++ ELES K +L E ++L F + +DE
Sbjct: 2186 LEAILERNENLEGELESLKENLPFTMNEGPFEEKLNFSQVHIMDE 2230
Score = 39.5 bits (88), Expect = 0.040
Identities = 34/144 (23%), Positives = 71/144 (49%), Gaps = 3/144 (2%)
Query: 529 EELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRL 588
EE + LK +I++ + + L+ ++N+ R + +L + E+ +++ K+ EIK L
Sbjct: 478 EEAIQLK-KISEAGKDLLYKQLSGRLQLVNKLRQEALDLELQMEKQKQEIAGKQKEIKDL 536
Query: 589 VESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSL 648
++ + + K +K +E+ ++I+N + +LE R + + I + K L
Sbjct: 537 QIAIDSLDS-KDPKHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDL 595
Query: 649 TLVLEKMSI-SNRVLKCSLLGVVT 671
L + I +N LK L GV++
Sbjct: 596 EEQLTEGQIAANEALKKDLEGVIS 619
Score = 37.1 bits (82), Expect = 0.21
Identities = 45/209 (21%), Positives = 80/209 (38%), Gaps = 11/209 (5%)
Query: 290 VERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDI 349
V+ + +E L + RSE +R + E + K T + K + E
Sbjct: 1418 VDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDA-KRSLLQTESD 1476
Query: 350 ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH------EMNLNIAKLIEIEKKYNDSI 403
A E+ S KD++ E+ I K++ + +
Sbjct: 1477 AEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCL 1536
Query: 404 EEKKT-LQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRK 462
+KK L E + L+ D+ +E ++ L E E +L+ K+ ELE K+ + ++
Sbjct: 1537 SKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRA---ELEKLKSQVTSQQ 1593
Query: 463 TEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
E+ R L K EE+ L+ + KA
Sbjct: 1594 QEMAVLDRQLGHKKEELHLLQGSMVQAKA 1622
Score = 36.7 bits (81), Expect = 0.28
Identities = 52/238 (21%), Positives = 100/238 (42%), Gaps = 32/238 (13%)
Query: 276 KDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKL 335
+ LS + + K VE+ + +L Q S++ LER DQ+L L
Sbjct: 1446 ESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKA----DQQLRSL 1501
Query: 336 TQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEI 395
KD LE + +E++ +K + + E+ + K IE+
Sbjct: 1502 QADAKD----LEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQ-KLQKDIEM 1556
Query: 396 EKKYNDS----IEEKKTL----QENIDDLRTDLLESELRVKDLVRELDEKE--------S 439
++ D ++E + L + ++ L++ + + + L R+L K+ S
Sbjct: 1557 AERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGS 1616
Query: 440 ILETKQCVQKELESTKTDLEHRKTEIEEYKRLL----FEKGE---EIDELKSKLSTEK 490
+++ K +Q+ L +T++ + I E K LL F+KGE +I E K++L+ K
Sbjct: 1617 MVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIK 1674
Score = 36.3 bits (80), Expect = 0.37
Identities = 69/348 (19%), Positives = 133/348 (38%), Gaps = 24/348 (6%)
Query: 273 SIMKDRLSRAEHQLKTNVERVVQLEAALEQAR-SESWS--LERTVXXXXXXXXXXXE--- 326
S + D + +AE Q+ E QLE A++ + SE+ L + + +
Sbjct: 454 SELHDEIEKAEQQILRATEEFKQLEEAIQLKKISEAGKDLLYKQLSGRLQLVNKLRQEAL 513
Query: 327 DFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMN 386
D + ++ K Q I ++D+ +A + L S S + + M +
Sbjct: 514 DLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSGK-EQQLDIMNKQYQ 572
Query: 387 LNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILET--K 444
++L EI + EE K L+E + + + +E KDL + + L T
Sbjct: 573 QLESRLDEILSRIAKETEEIKDLEEQLTE--GQIAANEALKKDLEGVISGLQEYLGTIKG 630
Query: 445 QCVQ-----KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS-TEKAIK---DI 495
Q Q ++L K L R TE+E+ + L + + ++ +L+ E A++ ++
Sbjct: 631 QATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEV 690
Query: 496 XXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGN 555
R+++ EEL + ++TQL + L
Sbjct: 691 NASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKV-TRLTQLEQSALQAELEKERQ 749
Query: 556 MINQQRDKL-FELTKRQE--EYDEKLQTKENEIKRLVESMTEQEHVLN 600
+ K F K QE E KL+ +++ L + + + ++ LN
Sbjct: 750 ALKNALGKAQFSEEKEQENSELHAKLKHLQDDNNLLKQQLKDFQNHLN 797
Score = 31.9 bits (69), Expect = 8.0
Identities = 71/372 (19%), Positives = 143/372 (38%), Gaps = 23/372 (6%)
Query: 275 MKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNK 334
+++ L E ++ + ++++ LE+ + L + ++ ++E
Sbjct: 1624 LQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEEN 1683
Query: 335 LTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH--EMNLNIAKL 392
L ++ + H ++ + LQ ++ K E L + L
Sbjct: 1684 LQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENL 1743
Query: 393 IEIEKKYNDSIEEKKTLQENIDDLRTDLLESELR-VKDLVRELD-EKESILETKQCVQKE 450
+I ++ IE +K L E D + + +E R ++ V L EKE + E +K+
Sbjct: 1744 QQISQQQKGEIEWQKQLLER-DKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKK 1802
Query: 451 LESTKTDL----EHRKTEIEEYKRL---LFEKGEEIDEL-KSKLSTEKAIKDIXXXXXXX 502
L TK L E+ K E ++L + + +E+D+L + KLS DI
Sbjct: 1803 LAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHN---DISAMQQQL 1859
Query: 503 XXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRD 562
++ + + L K+Q L E D+ N+ D
Sbjct: 1860 QEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQK--DISEWANRFED 1917
Query: 563 -KLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM----LNEKEEEHM 617
+ E TK+Q+ + + +EN++K + + M Q ++ +E K+ + KE++H
Sbjct: 1918 CQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQ 1977
Query: 618 NIINLLHNKLEL 629
L K +L
Sbjct: 1978 LEKELTDQKSKL 1989
>AL133553-3|CAI17859.1| 2363|Homo sapiens translocated promoter region
(to activated MET oncogene) protein.
Length = 2363
Score = 50.0 bits (114), Expect = 3e-05
Identities = 60/270 (22%), Positives = 114/270 (42%), Gaps = 34/270 (12%)
Query: 394 EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESI-LETKQCV---QK 449
+IEK ++ KK L+ ++ T ++++ D R+LD + ++ L TK+ + QK
Sbjct: 840 QIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQK 899
Query: 450 ELESTKTDLEHRKTEIEEYKRLLFEKG-----EEIDELKSKL-STEKAIKDIXXXXXXXX 503
E+ + K L + + ++ KG E++D+L S+L TE+ + D+
Sbjct: 900 EIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDL-------- 951
Query: 504 XXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDK 563
+ M + EE +N + Q+T+ L + Q K
Sbjct: 952 ----KERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKK 1007
Query: 564 LFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLL 623
L E+ K ++E +++ +R +ESM +Q L K ++ NE +E L
Sbjct: 1008 LMEVEKEKQEL-------QDDKRRAIESMEQQLSELKKTLSSVQ--NEVQEALQRASTAL 1058
Query: 624 HNKLELRNEADIDVIITLA---KYKKSLTL 650
N+ + R + I + KY++ L L
Sbjct: 1059 SNEQQARRDCQEQAKIAVEAQNKYERELML 1088
Score = 42.7 bits (96), Expect = 0.004
Identities = 58/291 (19%), Positives = 122/291 (41%), Gaps = 23/291 (7%)
Query: 331 ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIA 390
EL KL +K T +++ +A+++ + A I+ ++ +
Sbjct: 81 ELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRT-NERLSQELE 139
Query: 391 KLIEIEKKYNDSIEEKKT----LQENIDDLRTDLLESELRVKDLVRELDEKESILETKQC 446
L E K+ N+ ++E T LQ +D+L+ S++ VK + L++++ +L ++
Sbjct: 140 YLTEDVKRLNEKLKESNTTKGELQLKLDELQA----SDVSVKYREKRLEQEKELLHSQNT 195
Query: 447 VQKELESTKTD----LEHRK-TEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXX 501
TKTD L K EI E K L K EE+ L+ +++ K +
Sbjct: 196 WLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNE------- 248
Query: 502 XXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQR 561
+++ M+ + +N +++ L + A D+ N + +
Sbjct: 249 HLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYK-SAADDSEAKSNELTRAV 307
Query: 562 DKLFELTKRQEEYDEKLQTKENEIKRLVESM-TEQEHVLNKKEKEIKMLNE 611
++L +L K E ++ +Q E+++ + M E + + EKE++ N+
Sbjct: 308 EELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMLEKIGRLEKELENAND 358
Score = 41.5 bits (93), Expect = 0.010
Identities = 119/666 (17%), Positives = 262/666 (39%), Gaps = 59/666 (8%)
Query: 2 KQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFE------KSKKEL 55
+Q E + + + L +L + I S TK + Q + + E K + E+
Sbjct: 800 QQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEV 859
Query: 56 EDRQNQVMELYASLRNTHRKMKL-----LGQKVNLPSAEE------LHIMNVAKLSPEQL 104
E R L L +T R++ L K L +A++ H+ N+ Q
Sbjct: 860 EQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQS 919
Query: 105 LQLCAGGEPKALEHSTLDNKVTF--DVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMS 162
Q G+P E +D+ V+ + +N + + + + ++ E ++
Sbjct: 920 SQRTGKGQPSNKED--VDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLN 977
Query: 163 QEKGIST---KTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQ 219
+EK ++ K + +++KE +AE ++ L++ E KE ++ D R+ A E+M Q
Sbjct: 978 KEKQVTEEVRKNIEVRLKE-SAE---FQTQLEKKLMEVEKEKQELQDDKRR-AIESMEQQ 1032
Query: 220 LRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRL 279
L EL LS + + E ++ + + A R+ +
Sbjct: 1033 L--SELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHA 1090
Query: 280 SRAE--HQLKTNVERVVQLEAALEQA--RSESWSLERTVXXXXXXXXXXXEDFD-----Q 330
+ E K V ++ + LE+ ++ES LE E +
Sbjct: 1091 ADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCE 1150
Query: 331 ELNKLTQSIKDNTTHLED--IALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLN 388
+L K + + D L D +A +E +Q + ++ ++ E +
Sbjct: 1151 DLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIA 1210
Query: 389 IAK--LIEIEK-KYNDSIEE-KKTLQENIDDLRTDLLESELRVK------DLVRELDEKE 438
+ + ++E +Y +E ++ LQE D L + + ++ K +L+++ +
Sbjct: 1211 ETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMN 1270
Query: 439 SILETKQCVQKELESTKTDLEHRKTEIEEYK---RLLFEKGEEIDELKSKLSTEKAI--K 493
++ET + +++E E + DL+ + ++ + + L E E+ E L EK + +
Sbjct: 1271 VVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEE 1330
Query: 494 DIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDN--LN 551
D+ S+ + + + + L +I +L+ A N L
Sbjct: 1331 DVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLT 1390
Query: 552 DVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNE 611
+ N+I ++ L ++ +E + L K +I+ V+++T+ + + + + + + L
Sbjct: 1391 NNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKA 1450
Query: 612 KEEEHM 617
++++ M
Sbjct: 1451 QQDKVM 1456
Score = 35.9 bits (79), Expect = 0.49
Identities = 49/263 (18%), Positives = 108/263 (41%), Gaps = 14/263 (5%)
Query: 401 DSIEEK---KTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQC-VQKELESTKT 456
++IE K K LQE ++ + + E+E + + +L E+ + L ++ + +L+
Sbjct: 664 EAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASK 723
Query: 457 DLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXX 516
E + +E Y+R + E +L + ++ I +
Sbjct: 724 RYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIIN-TMTQDLRGANEKLAVAEVRAE 782
Query: 517 XXXRESQMKSYYEELMNLKNQITQLREFGA---FDNLNDVGNMINQQRDKLFELTKRQEE 573
+E +M E ++ + + + G NL + ++ + E +R
Sbjct: 783 NLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSET---ETKQRLSS 839
Query: 574 YDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEA 633
EKL+ + + +K+ +E+ EQ H L + ++++L+ K + NL N EL A
Sbjct: 840 QIEKLEHEISHLKKKLENEVEQRHTLT-RNLDVQLLDTKRQLDTE-TNLHLNTKELLKNA 897
Query: 634 DIDVIITLAKYKKSLTLVLEKMS 656
+ I TL ++ ++ + + S
Sbjct: 898 QKE-IATLKQHLSNMEVQVASQS 919
Score = 34.7 bits (76), Expect = 1.1
Identities = 48/252 (19%), Positives = 105/252 (41%), Gaps = 11/252 (4%)
Query: 379 KDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKE 438
K+++ + NIA + + + EK+ L + L +L VK L +L E
Sbjct: 97 KELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESN 156
Query: 439 SILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEID-ELKSKLSTEKAIKDIXX 497
+ Q EL+++ +++R+ +E+ K LL + ++ ELK+K A+
Sbjct: 157 TTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKG 216
Query: 498 XXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELM-NLKNQITQLREFGAFDNLNDVGNM 556
+ + +K+ E L ++++ +T+L+E A + +
Sbjct: 217 NEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKE--AKEQQASMEEK 274
Query: 557 INQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEH 616
+ + + +L+ + + + K NE+ R VE L+K KE N+ ++H
Sbjct: 275 FHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEE-------LHKLLKEAGEANKAIQDH 327
Query: 617 MNIINLLHNKLE 628
+ + +++E
Sbjct: 328 LLEVEQSKDQME 339
Score = 32.3 bits (70), Expect = 6.1
Identities = 39/167 (23%), Positives = 74/167 (44%), Gaps = 17/167 (10%)
Query: 57 DRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKAL 116
++ N+++EL +L N ++ L +++N H+ K + L +L E +A
Sbjct: 214 EKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQ---KHVEDLLTKLKEAKEQQAS 270
Query: 117 EHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESL--MSQEKGISTKTLTM 174
N++ + KL N+ S D E K E+ E L + +E G + K +
Sbjct: 271 MEEKFHNELNAHI-KLSNLYKSAADDSEA---KSNELTRAVEELHKLLKEAGEANKAIQD 326
Query: 175 KIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLR 221
+ E ++ S DQ+ E L++I + L +NAN+ ++ R
Sbjct: 327 HLLE-------VEQSKDQMEKEMLEKIGRLEKEL-ENANDLLSATKR 365
>AK074079-1|BAB84905.1| 1793|Homo sapiens FLJ00150 protein protein.
Length = 1793
Score = 50.0 bits (114), Expect = 3e-05
Identities = 58/247 (23%), Positives = 116/247 (46%), Gaps = 16/247 (6%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEE-KKTLQENIDDLRTDLLESELRVKDL 430
AS +S K+M+ E++ NI L++ +K +EE +T+Q+ + D ++ V+ L
Sbjct: 815 ASKRQSEKEME-ELHHNIDDLLQEKKSLECEVEELHRTVQKR--QQQKDFIDGN--VESL 869
Query: 431 VRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEK 490
+ EL+ ++S+ + V E+E + L R++E+ E RLL E E+ K K T+
Sbjct: 870 MTELEIEKSLKHHEDIVD-EIECIEKTLLKRRSELREADRLLAEAESELSCTKEK--TKN 926
Query: 491 AIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLRE--FGAFD 548
A++ + +K+ ++L +L+ L + +
Sbjct: 927 AVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKA-DQQLRSLQADAKDLEQHKIKQEE 985
Query: 549 NLNDVGNMINQQRDKLFE-LTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK 607
L ++ N I +D F+ L+K++E+ E+LQ + +I+ + E H+ KE E+
Sbjct: 986 ILKEI-NKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIE--MAERNEDHHLQVLKESEVL 1042
Query: 608 MLNEKEE 614
+ ++ E
Sbjct: 1043 LQAKRAE 1049
Score = 43.6 bits (98), Expect = 0.002
Identities = 90/506 (17%), Positives = 210/506 (41%), Gaps = 42/506 (8%)
Query: 2 KQEELEIQQN---QTDGCLYEDLNEQES-ITSESHKITKLKTVWQEKMVTFEKSKK--EL 55
K+EEL + Q Q L E L E+ +T + + I ++K++ +E ++F+K + ++
Sbjct: 1074 KKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEE--LSFQKGELNVQI 1131
Query: 56 EDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKA 115
+R+ Q+ + + ++++ ++++ E +I+++ +L +L L + +
Sbjct: 1132 SERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRV 1191
Query: 116 LEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMK 175
E L+ + + L + N ++ ++K I W + L+ ++K +
Sbjct: 1192 SE---LEKTQVAVLEEKLELEN-----LQQISQQQKGEIEWQKQLLERDK--------RE 1235
Query: 176 IKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELS-CALSDLNT 234
I+ AE+ L+S ++ L E +++ + D K +T + +E S S+L
Sbjct: 1236 IERMTAESRALQSCVECLSKE-KEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEK 1294
Query: 235 QNAEMRKQIHSGD--HHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVER 292
+RK D + + N + +++ L+ + L +
Sbjct: 1295 LELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQD 1354
Query: 293 VVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFD---QELNKLTQSIKDNTTHLEDI 349
++ + SE L++ + ++ + Q+L L I++N L
Sbjct: 1355 LLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQ 1414
Query: 350 ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTL 409
+ ++LQ + + ++ E+ +KL ++ K + E +TL
Sbjct: 1415 EMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTL 1474
Query: 410 QEN---IDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTE-I 465
QE + L L +++ ++ + ++L EK L +QKE +S + D + + +
Sbjct: 1475 QEEERWCESLEKTLSQTKRQLSEREQQLVEKSGEL---LALQKEADSMRADFSLLRNQFL 1531
Query: 466 EEYKRLLFEKGEEIDELKSKLSTEKA 491
E K+ EK ++ LK L +++
Sbjct: 1532 TERKKA--EK--QVASLKEALKIQRS 1553
Score = 43.2 bits (97), Expect = 0.003
Identities = 77/465 (16%), Positives = 187/465 (40%), Gaps = 25/465 (5%)
Query: 25 ESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVN 84
E ++ E + + +W++K+ ++ E+ N ME ++L ++ L Q+++
Sbjct: 1251 ECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEE--NSKME-QSNLEKLELNVRKLQQELD 1307
Query: 85 LPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCE 144
+ ++L + N +QL + E + + + + LL+
Sbjct: 1308 QLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLS 1367
Query: 145 ETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDI 204
E +K+I W +K TK +++ + E + LK ++ + L++ +
Sbjct: 1368 EQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERES 1427
Query: 205 IDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXX 264
+ + + T+ Q +L L+D ++ ++ ++ + +
Sbjct: 1428 EESKLETSKVTLKEQQH--QLEKELTDQKSKLDQVLSKVLAAEER------------VRT 1473
Query: 265 XXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXX 324
++ LS+ + QL +++V+ L + E+ S+
Sbjct: 1474 LQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTE 1533
Query: 325 XEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHE 384
+ ++++ L +++K + LE L +++ S + ++ + + E
Sbjct: 1534 RKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQDNHERARRLMKE 1593
Query: 385 MNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRT--DLLESELR--VKDLVRELDE---- 436
+N + E++K+ + + ++ E D +RT ++ E+R +K+L + L E
Sbjct: 1594 LNQMQYEYTELKKQMANQKDLERRQMEISDAMRTLKSEVKDEIRTSLKNLNQFLPELPAD 1653
Query: 437 KESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE 481
E+ILE + ++ ELES K +L E ++L F + +DE
Sbjct: 1654 LEAILERNENLEGELESLKENLPFTMNEGPFEEKLNFSQVHIMDE 1698
Score = 37.1 bits (82), Expect = 0.21
Identities = 45/209 (21%), Positives = 80/209 (38%), Gaps = 11/209 (5%)
Query: 290 VERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDI 349
V+ + +E L + RSE +R + E + K T + K + E
Sbjct: 886 VDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDA-KRSLLQTESD 944
Query: 350 ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH------EMNLNIAKLIEIEKKYNDSI 403
A E+ S KD++ E+ I K++ + +
Sbjct: 945 AEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCL 1004
Query: 404 EEKKT-LQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRK 462
+KK L E + L+ D+ +E ++ L E E +L+ K+ ELE K+ + ++
Sbjct: 1005 SKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRA---ELEKLKSQVTSQQ 1061
Query: 463 TEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
E+ R L K EE+ L+ + KA
Sbjct: 1062 QEMAVLDRQLGHKKEELHLLQGSMVQAKA 1090
Score = 36.7 bits (81), Expect = 0.28
Identities = 52/238 (21%), Positives = 100/238 (42%), Gaps = 32/238 (13%)
Query: 276 KDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKL 335
+ LS + + K VE+ + +L Q S++ LER DQ+L L
Sbjct: 914 ESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKA----DQQLRSL 969
Query: 336 TQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEI 395
KD LE + +E++ +K + + E+ + K IE+
Sbjct: 970 QADAKD----LEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQ-KLQKDIEM 1024
Query: 396 EKKYNDS----IEEKKTL----QENIDDLRTDLLESELRVKDLVRELDEKE--------S 439
++ D ++E + L + ++ L++ + + + L R+L K+ S
Sbjct: 1025 AERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGS 1084
Query: 440 ILETKQCVQKELESTKTDLEHRKTEIEEYKRLL----FEKGE---EIDELKSKLSTEK 490
+++ K +Q+ L +T++ + I E K LL F+KGE +I E K++L+ K
Sbjct: 1085 MVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIK 1142
Score = 33.5 bits (73), Expect = 2.6
Identities = 24/86 (27%), Positives = 45/86 (52%), Gaps = 6/86 (6%)
Query: 404 EEKKTLQENIDDLRTDLLESELRVKD---LVRELDEKESILETKQCVQKELESTKTDLEH 460
+EK+TL + + ++ + + E+ D + +EL E ES L+ + V L+ T+ DL
Sbjct: 118 DEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEVNASLQQTQGDLSA 177
Query: 461 RKTEIEEYKRLLFEKGEEIDELKSKL 486
+ E+E L + E ++LK +L
Sbjct: 178 YEAELEARLNL---RDAEANQLKEEL 200
Score = 31.9 bits (69), Expect = 8.0
Identities = 71/372 (19%), Positives = 143/372 (38%), Gaps = 23/372 (6%)
Query: 275 MKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNK 334
+++ L E ++ + ++++ LE+ + L + ++ ++E
Sbjct: 1092 LQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEEN 1151
Query: 335 LTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH--EMNLNIAKL 392
L ++ + H ++ + LQ ++ K E L + L
Sbjct: 1152 LQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENL 1211
Query: 393 IEIEKKYNDSIEEKKTLQENIDDLRTDLLESELR-VKDLVRELD-EKESILETKQCVQKE 450
+I ++ IE +K L E D + + +E R ++ V L EKE + E +K+
Sbjct: 1212 QQISQQQKGEIEWQKQLLER-DKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKK 1270
Query: 451 LESTKTDL----EHRKTEIEEYKRL---LFEKGEEIDEL-KSKLSTEKAIKDIXXXXXXX 502
L TK L E+ K E ++L + + +E+D+L + KLS DI
Sbjct: 1271 LAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHN---DISAMQQQL 1327
Query: 503 XXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRD 562
++ + + L K+Q L E D+ N+ D
Sbjct: 1328 QEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQK--DISEWANRFED 1385
Query: 563 -KLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM----LNEKEEEHM 617
+ E TK+Q+ + + +EN++K + + M Q ++ +E K+ + KE++H
Sbjct: 1386 CQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQ 1445
Query: 618 NIINLLHNKLEL 629
L K +L
Sbjct: 1446 LEKELTDQKSKL 1457
>AK002084-1|BAA92077.1| 495|Homo sapiens protein ( Homo sapiens
cDNA FLJ11222 fis, clone PLACE1008177. ).
Length = 495
Score = 50.0 bits (114), Expect = 3e-05
Identities = 67/312 (21%), Positives = 138/312 (44%), Gaps = 38/312 (12%)
Query: 333 NKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKL 392
N++ Q+ DN + LQ+ A NK +K+++ + +A
Sbjct: 40 NQMVQNENDNRVQRKQFL---RLLQNEQFELDMEEAIQKAEENKRLKELQLKQEEKLA-- 94
Query: 393 IEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELE 452
+E+ K ++S++++K +++ + + +L E E ++K + I E K ++ E
Sbjct: 95 MELAKLKHESLKDEK-MRQQVRENSIELRELEKKLKAAYMNKERAAQIAE-KDAIK--YE 150
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXX 512
K D E KT +EE+KR++ E+ D+ ++K + + D+
Sbjct: 151 QMKRDAEIAKTMMEEHKRIIKEENAAEDK-RNKAKAQYYL-DLEKQLEE----------- 197
Query: 513 XXXXXXXRESQMKSYYEELMNLKNQITQL-REFGAFDNLNDVGNM--INQQRDKLFELTK 569
+E + + YE+L+ K I ++ R+ D L + +N R + E K
Sbjct: 198 -------QEKKKQEAYEQLLKEKLMIDEIVRKIYEEDQLEKQQKLEKMNAMRRYIEEFQK 250
Query: 570 RQEEYDEKLQTK-ENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
Q + +K + + E E ++++E Q+ ++E + + E EE+ + + N L KLE
Sbjct: 251 EQALWRKKKREEMEEENRKIIEFANMQQQ---REEDRMAKVQENEEKRLQLQNALTQKLE 307
Query: 629 --LRNEADIDVI 638
LR D++ +
Sbjct: 308 EMLRQREDLEQV 319
>AF513978-1|AAP43846.1| 2325|Homo sapiens CENTRIOLIN protein.
Length = 2325
Score = 50.0 bits (114), Expect = 3e-05
Identities = 58/247 (23%), Positives = 116/247 (46%), Gaps = 16/247 (6%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEE-KKTLQENIDDLRTDLLESELRVKDL 430
AS +S K+M+ E++ NI L++ +K +EE +T+Q+ + D ++ V+ L
Sbjct: 1347 ASKRQSEKEME-ELHHNIDDLLQEKKSLECEVEELHRTVQKR--QQQKDFIDGN--VESL 1401
Query: 431 VRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEK 490
+ EL+ ++S+ + V E+E + L R++E+ E RLL E E+ K K T+
Sbjct: 1402 MTELEIEKSLKHHEDIVD-EIECIEKTLLKRRSELREADRLLAEAESELSCTKEK--TKN 1458
Query: 491 AIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLRE--FGAFD 548
A++ + +K+ ++L +L+ L + +
Sbjct: 1459 AVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKA-DQQLRSLQADAKDLEQHKIKQEE 1517
Query: 549 NLNDVGNMINQQRDKLFE-LTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK 607
L ++ N I +D F+ L+K++E+ E+LQ + +I+ + E H+ KE E+
Sbjct: 1518 ILKEI-NKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIE--MAERNEDHHLQVLKESEVL 1574
Query: 608 MLNEKEE 614
+ ++ E
Sbjct: 1575 LQAKRAE 1581
Score = 43.6 bits (98), Expect = 0.002
Identities = 90/506 (17%), Positives = 210/506 (41%), Gaps = 42/506 (8%)
Query: 2 KQEELEIQQN---QTDGCLYEDLNEQES-ITSESHKITKLKTVWQEKMVTFEKSKK--EL 55
K+EEL + Q Q L E L E+ +T + + I ++K++ +E ++F+K + ++
Sbjct: 1606 KKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEE--LSFQKGELNVQI 1663
Query: 56 EDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKA 115
+R+ Q+ + + ++++ ++++ E +I+++ +L +L L + +
Sbjct: 1664 SERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRV 1723
Query: 116 LEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMK 175
E L+ + + L + N ++ ++K I W + L+ ++K +
Sbjct: 1724 SE---LEKTQVAVLEEKLELEN-----LQQISQQQKGEIEWQKQLLERDK--------RE 1767
Query: 176 IKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELS-CALSDLNT 234
I+ AE+ L+S ++ L E +++ + D K +T + +E S S+L
Sbjct: 1768 IERMTAESRALQSCVECLSKE-KEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEK 1826
Query: 235 QNAEMRKQIHSGD--HHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVER 292
+RK D + + N + +++ L+ + L +
Sbjct: 1827 LELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQD 1886
Query: 293 VVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFD---QELNKLTQSIKDNTTHLEDI 349
++ + SE L++ + ++ + Q+L L I++N L
Sbjct: 1887 LLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQ 1946
Query: 350 ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTL 409
+ ++LQ + + ++ E+ +KL ++ K + E +TL
Sbjct: 1947 EMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTL 2006
Query: 410 QEN---IDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTE-I 465
QE + L L +++ ++ + ++L EK L +QKE +S + D + + +
Sbjct: 2007 QEEERWCESLEKTLSQTKRQLSEREQQLVEKSGEL---LALQKEADSMRADFSLLRNQFL 2063
Query: 466 EEYKRLLFEKGEEIDELKSKLSTEKA 491
E K+ EK ++ LK L +++
Sbjct: 2064 TERKKA--EK--QVASLKEALKIQRS 2085
Score = 43.2 bits (97), Expect = 0.003
Identities = 77/465 (16%), Positives = 187/465 (40%), Gaps = 25/465 (5%)
Query: 25 ESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVN 84
E ++ E + + +W++K+ ++ E+ N ME ++L ++ L Q+++
Sbjct: 1783 ECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEE--NSKME-QSNLEKLELNVRKLQQELD 1839
Query: 85 LPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCE 144
+ ++L + N +QL + E + + + + LL+
Sbjct: 1840 QLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLS 1899
Query: 145 ETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDI 204
E +K+I W +K TK +++ + E + LK ++ + L++ +
Sbjct: 1900 EQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERES 1959
Query: 205 IDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXX 264
+ + + T+ Q +L L+D ++ ++ ++ + +
Sbjct: 1960 EESKLETSKVTLKEQQH--QLEKELTDQKSKLDQVLSKVLAAEER------------VRT 2005
Query: 265 XXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXX 324
++ LS+ + QL +++V+ L + E+ S+
Sbjct: 2006 LQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTE 2065
Query: 325 XEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHE 384
+ ++++ L +++K + LE L +++ S + ++ + + E
Sbjct: 2066 RKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQDNHERARRLMKE 2125
Query: 385 MNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRT--DLLESELR--VKDLVRELDE---- 436
+N + E++K+ + + ++ E D +RT ++ E+R +K+L + L E
Sbjct: 2126 LNQMQYEYTELKKQMANQKDLERRQMEISDAMRTLKSEVKDEIRTSLKNLNQFLPELPAD 2185
Query: 437 KESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE 481
E+ILE + ++ ELES K +L E ++L F + +DE
Sbjct: 2186 LEAILERNENLEGELESLKENLPFTMNEGPFEEKLNFSQVHIMDE 2230
Score = 39.5 bits (88), Expect = 0.040
Identities = 34/144 (23%), Positives = 71/144 (49%), Gaps = 3/144 (2%)
Query: 529 EELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRL 588
EE + LK +I++ + + L+ ++N+ R + +L + E+ +++ K+ EIK L
Sbjct: 478 EEAIQLK-KISEAGKDLLYKQLSGRLQLVNKLRQEALDLELQMEKQKQEIAGKQKEIKDL 536
Query: 589 VESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSL 648
++ + + K +K +E+ ++I+N + +LE R + + I + K L
Sbjct: 537 QIAIDSLDS-KDPKHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDL 595
Query: 649 TLVLEKMSI-SNRVLKCSLLGVVT 671
L + I +N LK L GV++
Sbjct: 596 EEQLTEGQIAANEALKKDLEGVIS 619
Score = 37.1 bits (82), Expect = 0.21
Identities = 45/209 (21%), Positives = 80/209 (38%), Gaps = 11/209 (5%)
Query: 290 VERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDI 349
V+ + +E L + RSE +R + E + K T + K + E
Sbjct: 1418 VDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDA-KRSLLQTESD 1476
Query: 350 ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH------EMNLNIAKLIEIEKKYNDSI 403
A E+ S KD++ E+ I K++ + +
Sbjct: 1477 AEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCL 1536
Query: 404 EEKKT-LQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRK 462
+KK L E + L+ D+ +E ++ L E E +L+ K+ ELE K+ + ++
Sbjct: 1537 SKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRA---ELEKLKSQVTSQQ 1593
Query: 463 TEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
E+ R L K EE+ L+ + KA
Sbjct: 1594 QEMAVLDRQLGHKKEELHLLQGSMVQAKA 1622
Score = 36.7 bits (81), Expect = 0.28
Identities = 52/238 (21%), Positives = 100/238 (42%), Gaps = 32/238 (13%)
Query: 276 KDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKL 335
+ LS + + K VE+ + +L Q S++ LER DQ+L L
Sbjct: 1446 ESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKA----DQQLRSL 1501
Query: 336 TQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEI 395
KD LE + +E++ +K + + E+ + K IE+
Sbjct: 1502 QADAKD----LEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQ-KLQKDIEM 1556
Query: 396 EKKYNDS----IEEKKTL----QENIDDLRTDLLESELRVKDLVRELDEKE--------S 439
++ D ++E + L + ++ L++ + + + L R+L K+ S
Sbjct: 1557 AERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGS 1616
Query: 440 ILETKQCVQKELESTKTDLEHRKTEIEEYKRLL----FEKGE---EIDELKSKLSTEK 490
+++ K +Q+ L +T++ + I E K LL F+KGE +I E K++L+ K
Sbjct: 1617 MVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIK 1674
Score = 36.3 bits (80), Expect = 0.37
Identities = 69/348 (19%), Positives = 133/348 (38%), Gaps = 24/348 (6%)
Query: 273 SIMKDRLSRAEHQLKTNVERVVQLEAALEQAR-SESWS--LERTVXXXXXXXXXXXE--- 326
S + D + +AE Q+ E QLE A++ + SE+ L + + +
Sbjct: 454 SELHDEIEKAEQQILRATEEFKQLEEAIQLKKISEAGKDLLYKQLSGRLQLVNKLRQEAL 513
Query: 327 DFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMN 386
D + ++ K Q I ++D+ +A + L S S + + M +
Sbjct: 514 DLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSGK-EQQLDIMNKQYQ 572
Query: 387 LNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILET--K 444
++L EI + EE K L+E + + + +E KDL + + L T
Sbjct: 573 QLESRLDEILSRIAKETEEIKDLEEQLTE--GQIAANEALKKDLEGVISGLQEYLGTIKG 630
Query: 445 QCVQ-----KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS-TEKAIK---DI 495
Q Q ++L K L R TE+E+ + L + + ++ +L+ E A++ ++
Sbjct: 631 QATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEV 690
Query: 496 XXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGN 555
R+++ EEL + ++TQL + L
Sbjct: 691 NASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKV-TRLTQLEQSALQAELEKERQ 749
Query: 556 MINQQRDKL-FELTKRQE--EYDEKLQTKENEIKRLVESMTEQEHVLN 600
+ K F K QE E KL+ +++ L + + + ++ LN
Sbjct: 750 ALKNALGKAQFSEEKEQENSELHAKLKHLQDDNNLLKQQLKDFQNHLN 797
Score = 31.9 bits (69), Expect = 8.0
Identities = 71/372 (19%), Positives = 143/372 (38%), Gaps = 23/372 (6%)
Query: 275 MKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNK 334
+++ L E ++ + ++++ LE+ + L + ++ ++E
Sbjct: 1624 LQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEEN 1683
Query: 335 LTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH--EMNLNIAKL 392
L ++ + H ++ + LQ ++ K E L + L
Sbjct: 1684 LQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENL 1743
Query: 393 IEIEKKYNDSIEEKKTLQENIDDLRTDLLESELR-VKDLVRELD-EKESILETKQCVQKE 450
+I ++ IE +K L E D + + +E R ++ V L EKE + E +K+
Sbjct: 1744 QQISQQQKGEIEWQKQLLER-DKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKK 1802
Query: 451 LESTKTDL----EHRKTEIEEYKRL---LFEKGEEIDEL-KSKLSTEKAIKDIXXXXXXX 502
L TK L E+ K E ++L + + +E+D+L + KLS DI
Sbjct: 1803 LAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHN---DISAMQQQL 1859
Query: 503 XXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRD 562
++ + + L K+Q L E D+ N+ D
Sbjct: 1860 QEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQK--DISEWANRFED 1917
Query: 563 -KLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM----LNEKEEEHM 617
+ E TK+Q+ + + +EN++K + + M Q ++ +E K+ + KE++H
Sbjct: 1918 CQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQ 1977
Query: 618 NIINLLHNKLEL 629
L K +L
Sbjct: 1978 LEKELTDQKSKL 1989
>AF083322-1|AAC32373.1| 994|Homo sapiens centriole associated
protein CEP110 protein.
Length = 994
Score = 50.0 bits (114), Expect = 3e-05
Identities = 58/247 (23%), Positives = 116/247 (46%), Gaps = 16/247 (6%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEE-KKTLQENIDDLRTDLLESELRVKDL 430
AS +S K+M+ E++ NI L++ +K +EE +T+Q+ + D ++ V+ L
Sbjct: 16 ASKRQSEKEME-ELHHNIDDLLQEKKSLECEVEELHRTVQKR--QRQKDFIDGN--VESL 70
Query: 431 VRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEK 490
+ EL+ ++S+ + V E+E + L R++E+ E RLL E E+ K K T+
Sbjct: 71 MTELEIEKSLKHHEDIVD-EIECIEKTLLKRRSELREADRLLAEAESELSCTKEK--TKN 127
Query: 491 AIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLRE--FGAFD 548
A++ + +K+ ++L +L+ L + +
Sbjct: 128 AVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKA-DQQLRSLQADAKDLEQHKIKQEE 186
Query: 549 NLNDVGNMINQQRDKLFE-LTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK 607
L ++ N I +D F+ L+K++E+ E+LQ + +I+ + E H+ KE E+
Sbjct: 187 ILKEI-NKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIE--MAERNEDHHLQVLKESEVL 243
Query: 608 MLNEKEE 614
+ ++ E
Sbjct: 244 LQAKRAE 250
Score = 44.0 bits (99), Expect = 0.002
Identities = 90/506 (17%), Positives = 211/506 (41%), Gaps = 42/506 (8%)
Query: 2 KQEELEIQQN---QTDGCLYEDLNEQES-ITSESHKITKLKTVWQEKMVTFEKSKK--EL 55
K+EEL + Q Q L E L E+ +T + + I ++K++ +E ++F+K + ++
Sbjct: 275 KKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEE--LSFQKGELNVQI 332
Query: 56 EDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKA 115
+R+ Q+ + + ++++ ++++ E +I+++ +L +L L + +
Sbjct: 333 SERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELQNILDMLQLENHELQGLKLQHDQRV 392
Query: 116 LEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMK 175
E L+ + + L + N ++ ++K I W + L+ ++K +
Sbjct: 393 SE---LEKTQVAVLEEKLELEN-----LQQISQQQKGEIEWQKQLLERDK--------RE 436
Query: 176 IKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELS-CALSDLNT 234
I+ AE+ L+S ++ L E +++ + D K +T + +E S S+L
Sbjct: 437 IERMTAESRALQSCVECLSKE-KEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEK 495
Query: 235 QNAEMRKQIHSGD--HHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVER 292
+ +RK D + + N + +++ L+ + L +
Sbjct: 496 LDLNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQD 555
Query: 293 VVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFD---QELNKLTQSIKDNTTHLEDI 349
++ + SE L++ + ++ + Q+L L I++N L
Sbjct: 556 LLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQ 615
Query: 350 ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTL 409
+ ++LQ + + ++ E+ +KL ++ K + E +TL
Sbjct: 616 EMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTL 675
Query: 410 QEN---IDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTE-I 465
QE + L L +++ ++ + ++L EK L +QKE +S + D + + +
Sbjct: 676 QEEERWCESLEKTLSQTKRQLSEREQQLVEKSGEL---LALQKEADSMRADFSLLRNQFL 732
Query: 466 EEYKRLLFEKGEEIDELKSKLSTEKA 491
E K+ EK ++ LK L +++
Sbjct: 733 TERKKA--EK--QVASLKEALKIQRS 754
Score = 42.7 bits (96), Expect = 0.004
Identities = 77/465 (16%), Positives = 187/465 (40%), Gaps = 25/465 (5%)
Query: 25 ESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVN 84
E ++ E + + +W++K+ ++ E+ N ME ++L ++ L Q+++
Sbjct: 452 ECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEE--NSKME-QSNLEKLDLNVRKLQQELD 508
Query: 85 LPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCE 144
+ ++L + N +QL + E + + + + LL+
Sbjct: 509 QLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLS 568
Query: 145 ETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDI 204
E +K+I W +K TK +++ + E + LK ++ + L++ +
Sbjct: 569 EQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERES 628
Query: 205 IDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXX 264
+ + + T+ Q +L L+D ++ ++ ++ + +
Sbjct: 629 EESKLETSKVTLKEQQH--QLEKELTDQKSKLDQVLSKVLAAEER------------VRT 674
Query: 265 XXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXX 324
++ LS+ + QL +++V+ L + E+ S+
Sbjct: 675 LQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTE 734
Query: 325 XEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHE 384
+ ++++ L +++K + LE L +++ S + ++ + + E
Sbjct: 735 RKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQDNHERARRLMKE 794
Query: 385 MNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRT--DLLESELR--VKDLVRELDE---- 436
+N + E++K+ + + ++ E D +RT ++ E+R +K+L + L E
Sbjct: 795 LNQMQYEYTELKKQMANQKDLERRQMEISDAMRTLKSEVKDEIRTSLKNLNQFLPELPAD 854
Query: 437 KESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE 481
E+ILE + ++ ELES K +L E ++L F + +DE
Sbjct: 855 LEAILERNENLEGELESLKENLPFTMNEGPFEEKLNFSQVHIMDE 899
Score = 37.1 bits (82), Expect = 0.21
Identities = 45/209 (21%), Positives = 80/209 (38%), Gaps = 11/209 (5%)
Query: 290 VERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDI 349
V+ + +E L + RSE +R + E + K T + K + E
Sbjct: 87 VDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDA-KRSLLQTESD 145
Query: 350 ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH------EMNLNIAKLIEIEKKYNDSI 403
A E+ S KD++ E+ I K++ + +
Sbjct: 146 AEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCL 205
Query: 404 EEKKT-LQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRK 462
+KK L E + L+ D+ +E ++ L E E +L+ K+ ELE K+ + ++
Sbjct: 206 SKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRA---ELEKLKSQVTSQQ 262
Query: 463 TEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
E+ R L K EE+ L+ + KA
Sbjct: 263 QEMAVLDRQLGHKKEELHLLQGSMVQAKA 291
Score = 36.7 bits (81), Expect = 0.28
Identities = 52/238 (21%), Positives = 100/238 (42%), Gaps = 32/238 (13%)
Query: 276 KDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKL 335
+ LS + + K VE+ + +L Q S++ LER DQ+L L
Sbjct: 115 ESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKA----DQQLRSL 170
Query: 336 TQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEI 395
KD LE + +E++ +K + + E+ + K IE+
Sbjct: 171 QADAKD----LEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQ-KLQKDIEM 225
Query: 396 EKKYNDS----IEEKKTL----QENIDDLRTDLLESELRVKDLVRELDEKE--------S 439
++ D ++E + L + ++ L++ + + + L R+L K+ S
Sbjct: 226 AERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGS 285
Query: 440 ILETKQCVQKELESTKTDLEHRKTEIEEYKRLL----FEKGE---EIDELKSKLSTEK 490
+++ K +Q+ L +T++ + I E K LL F+KGE +I E K++L+ K
Sbjct: 286 MVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIK 343
Score = 31.9 bits (69), Expect = 8.0
Identities = 71/372 (19%), Positives = 143/372 (38%), Gaps = 23/372 (6%)
Query: 275 MKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNK 334
+++ L E ++ + ++++ LE+ + L + ++ ++E
Sbjct: 293 LQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEEN 352
Query: 335 LTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH--EMNLNIAKL 392
L ++ + H ++ + LQ ++ K E L + L
Sbjct: 353 LQVVLRQMSKHKTELQNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENL 412
Query: 393 IEIEKKYNDSIEEKKTLQENIDDLRTDLLESELR-VKDLVRELD-EKESILETKQCVQKE 450
+I ++ IE +K L E D + + +E R ++ V L EKE + E +K+
Sbjct: 413 QQISQQQKGEIEWQKQLLER-DKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKK 471
Query: 451 LESTKTDL----EHRKTEIEEYKRL---LFEKGEEIDEL-KSKLSTEKAIKDIXXXXXXX 502
L TK L E+ K E ++L + + +E+D+L + KLS DI
Sbjct: 472 LAQTKRVLAAAEENSKMEQSNLEKLDLNVRKLQQELDQLNRDKLSLHN---DISAMQQQL 528
Query: 503 XXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRD 562
++ + + L K+Q L E D+ N+ D
Sbjct: 529 QEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQK--DISEWANRFED 586
Query: 563 -KLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM----LNEKEEEHM 617
+ E TK+Q+ + + +EN++K + + M Q ++ +E K+ + KE++H
Sbjct: 587 CQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQ 646
Query: 618 NIINLLHNKLEL 629
L K +L
Sbjct: 647 LEKELTDQKSKL 658
>AF007217-1|AAD09135.1| 1978|Homo sapiens Trip230 protein.
Length = 1978
Score = 50.0 bits (114), Expect = 3e-05
Identities = 123/593 (20%), Positives = 238/593 (40%), Gaps = 68/593 (11%)
Query: 42 QEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSP 101
QE V+ +K EL++ Q E + +RN M+ L Q N + L + +
Sbjct: 596 QESNVSIQKENLELKEHIRQNEEELSRIRN--ELMQSLNQDSNSNFKDTL--LKEREAEV 651
Query: 102 EQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLM 161
L Q + E + L + KV FDV K+ N LV CE+ + +E + L
Sbjct: 652 RNLKQNLS--ELEQLNENL--KKVAFDV-KMEN--EKLVLACEDVRHQLEECLAGNNQL- 703
Query: 162 SQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLR 221
S EK +TL M+ E AE K L + ++ K I ++ + +N N T ALQL
Sbjct: 704 SLEKNTIVETLKMEKGEIEAELCWAKKRLLEEANKYEKTIEELSNA--RNLN-TSALQLE 760
Query: 222 TKELSCALSDLNTQNAEMRKQIHS--GDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRL 279
+ L + + AE++K I DH + I ++L
Sbjct: 761 HEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKL 820
Query: 280 SRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQ--ELNKLTQ 337
+L+ +++ Q E R +R++ E+ ++ E T
Sbjct: 821 KERSSKLQEELDKYSQALRKNEILRQTIEEKDRSLGSMKEENNHLQEELERLREEQSRTA 880
Query: 338 SIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEK 397
+ D T LA E Q +++ I + +++ + + + ++ +K
Sbjct: 881 PVADPKTLDSVTELASEVSQ---LNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQK 937
Query: 398 KYNDSIEEKKTLQENIDDLRTDL-LESELRVKDLVRELDEKESILETKQCVQKELESTKT 456
K ++E + E ++ T L LE + +K L + +++ ++ L ++ +++++ +
Sbjct: 938 K---EMDEFRYQHEQMNATHTQLFLEKDEEIKSLQKTIEQIKTQLHEER---QDIQTDNS 991
Query: 457 DLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXX 516
D+ ++T+++ L E G E +L SK TE+ +K I
Sbjct: 992 DI-FQETKVQS---LNIENGSEKHDL-SKAETERLVKGIKE------------------- 1027
Query: 517 XXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDE 576
RE ++K E+ ++L QI QL + ++VG + + K E+
Sbjct: 1028 ---RELEIKLLNEKNISLTKQIDQLSK-------DEVGKLTQIIQQKDLEIQALHARISS 1077
Query: 577 KLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLEL 629
T++ +V + + ++EK +LNEK E+ ++ H +++
Sbjct: 1078 TSHTQD-----VVYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMDI 1125
Score = 46.0 bits (104), Expect = 5e-04
Identities = 109/615 (17%), Positives = 254/615 (41%), Gaps = 56/615 (9%)
Query: 21 LNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRK----- 75
LN+ S+ ++ K+ V +++ + K+EL+ ++ Y +++T +
Sbjct: 407 LNQDNSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKSTATRDISLD 466
Query: 76 MKLLGQKVNLPSAE-ELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLN 134
+L ++NL + E EL+ K + ++ +A +H L + ++K N
Sbjct: 467 SELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMIL---IKAQLSKQQN 523
Query: 135 IPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLR 194
+S++ K ++ L K+ ++ E +K TK L ++ ++++ + L +
Sbjct: 524 EGDSIISKLKQDLNDEKKRVHQLED----DKMDITKELDVQFVLL-IQSEVALNDLHLTK 578
Query: 195 TEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYAN 254
+ ++ +++D L K+ +++Q EL + QN E +I
Sbjct: 579 QKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIR----QNEEELSRI----------- 623
Query: 255 RNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTV 314
RN +++K+R + + LK N+ + QL L++ + +
Sbjct: 624 RNELMQSLNQDSNSNFKDTLLKEREAEVRN-LKQNLSELEQLNENLKKVAFDVKMENEKL 682
Query: 315 XXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASY 374
E+ N+L S++ NT +E + + + ++++ + Y
Sbjct: 683 VLACEDVRHQLEECLAGNNQL--SLEKNTI-VETLKMEKGEIEAELCWAKKRLLEEANKY 739
Query: 375 NKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKK-----TLQENIDDLRT------DLLES 423
K+I+++ + NLN + L ++E ++ + +KK L++NI+ + T D+L S
Sbjct: 740 EKTIEELSNARNLNTSAL-QLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLSS 798
Query: 424 EL-RVKDLVRELDEK----ESILETKQCVQKELESTKTDL---EHRKTEIEEYKRLLFEK 475
L K L + +++K E + E +Q+EL+ L E + IEE R L
Sbjct: 799 SLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTIEEKDRSLGSM 858
Query: 476 GEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLK 535
EE + L+ +L + +++ + + +K + EE +
Sbjct: 859 KEENNHLQEEL---ERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEIKHH 915
Query: 536 NQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQ 595
+I + + L + + + ++ + + + K+ EIK L +++ +
Sbjct: 916 QKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDEEIKSLQKTIEQI 975
Query: 596 EHVLNKKEKEIKMLN 610
+ L+++ ++I+ N
Sbjct: 976 KTQLHEERQDIQTDN 990
Score = 36.3 bits (80), Expect = 0.37
Identities = 20/73 (27%), Positives = 39/73 (53%), Gaps = 1/73 (1%)
Query: 404 EEKKTLQENIDDLRTDLLESELRVKDLVRELDE-KESILETKQCVQKELESTKTDLEHRK 462
E + LQ+ +++LR L E + ++ L +SI T + +KE E T ++++ K
Sbjct: 1340 ESSELLQQELEELRKSLQEKDATIRTLQENNHRLSDSIAATSELERKEHEQTDSEIKQLK 1399
Query: 463 TEIEEYKRLLFEK 475
+ + ++LL EK
Sbjct: 1400 EKQDVLQKLLKEK 1412
Score = 33.9 bits (74), Expect = 2.0
Identities = 19/75 (25%), Positives = 40/75 (53%), Gaps = 1/75 (1%)
Query: 3 QEELE-IQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQ 61
QEELE +++ Q+ D +S+T + ++++L T+ + + +K +ED+
Sbjct: 866 QEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQS 925
Query: 62 VMELYASLRNTHRKM 76
M+L SL+ ++M
Sbjct: 926 KMQLLQSLQEQKKEM 940
>AC012487-1|AAX88838.1| 1583|Homo sapiens unknown protein.
Length = 1583
Score = 50.0 bits (114), Expect = 3e-05
Identities = 114/659 (17%), Positives = 256/659 (38%), Gaps = 37/659 (5%)
Query: 24 QESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKV 83
QE + ++ L ++++ V K +E++ + + ++N + K +L Q +
Sbjct: 718 QEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNL 777
Query: 84 NLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVN-KLLNIPNSLVDK 142
+ E + +++ E+ + C E + L+ L+ K D +L+ + +SL
Sbjct: 778 LIQVEEVSQTCSKSEIHNEK--EKCFIKEHENLK-PLLEQKELRDRRAELILLKDSLAKS 834
Query: 143 CE---ETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLD-QLRTEFL 198
+ L KE+ E+L + K K +K+ A+ +L S + Q E L
Sbjct: 835 PSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEEL 894
Query: 199 KEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXX 258
+ + D L + + + K L + Q +++ ++ +H R
Sbjct: 895 ESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLR 954
Query: 259 XXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXX 318
++ R+ + K ++++++ A E + +
Sbjct: 955 NSTLQCETINSDNEDLLA-RIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKI 1013
Query: 319 XXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSI 378
+ ++ +L + K ++++ L ++ Q A Y + +
Sbjct: 1014 KEHATTVNELEELQVQLQKQKKQLQKTMQELELVKKDAQQTTLMNMEI-----ADYERLM 1068
Query: 379 KDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLL---ESELRVKDLVRELD 435
K++ ++ K+ ++E++ ++++TLQE I L++ + E ++K L+ +
Sbjct: 1069 KELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLL--VK 1126
Query: 436 EKESILETKQCVQKEL---ESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLST---- 488
K+ + ++KQ L S K +LE + ++E YK L E E ++ L T
Sbjct: 1127 TKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQ 1186
Query: 489 -EKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQ-ITQLREFGA 546
++ + ES + L KN+ ++Q GA
Sbjct: 1187 HQRTLSAYQQRVTALQEECRAAKAEQATVTSEFESYKVRVHNVLKQQKNKSMSQAETEGA 1246
Query: 547 FDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTE--QEHVLNKKEK 604
+ +I+Q + KL + + +LQT ++E L+E + QE V + E
Sbjct: 1247 KQEREHLEMLIDQLKIKLQDSQNNLQINVSELQTLQSEHDTLLERHNKMLQETVSKEAEL 1306
Query: 605 EIKMLNEKEE------EHMNIINLLHNKLE-LRNEADIDVIITLAKYKKSLTLVLEKMS 656
K+ + + E EH ++ L ++ E LRN V +++K++ + +++S
Sbjct: 1307 REKLCSIQSENMMMKSEHTQTVSQLTSQNEVLRNSFRDQVRHLQEEHRKTVETLQQQLS 1365
Score = 49.6 bits (113), Expect = 4e-05
Identities = 64/303 (21%), Positives = 132/303 (43%), Gaps = 24/303 (7%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDL----V 431
K ++D + E+ L L + ND + K L+E I++L + E E ++ + V
Sbjct: 815 KELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAV 874
Query: 432 RELDEKESILETKQCVQKELESTKTDLEHRKTEI-------EEYKRLLFE---KGEEIDE 481
+ E +S + Q V++ELES +++ + + E YK LL E + E++D
Sbjct: 875 KAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDV 934
Query: 482 LKSKLST-EKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQ 540
K + + E I+D+ +++++ L+ QI +
Sbjct: 935 EKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLL----ARIETLQSNAKLLEVQILE 990
Query: 541 LREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLN 600
++ A + + Q+ K+ E E +E + + K+L ++M E E ++
Sbjct: 991 VQRAKAMVDKELEAEKL-QKEQKIKEHATTVNELEELQVQLQKQKKQLQKTMQELE-LVK 1048
Query: 601 KKEKEIKMLNEKEEEHMNIINLLHNKLELRNE--ADIDVIITLAKYKKSLTLVLEKMSIS 658
K ++ ++N + ++ ++ L+ KL +N D++ I + K K+ TL E S+
Sbjct: 1049 KDAQQTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQE-TLQEEITSLQ 1107
Query: 659 NRV 661
+ V
Sbjct: 1108 SSV 1110
Score = 48.8 bits (111), Expect = 7e-05
Identities = 60/307 (19%), Positives = 127/307 (41%), Gaps = 15/307 (4%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD 435
K K+ + ++N ++ +K+ + S +E +T++E ++ LR++ + ++DL++ +
Sbjct: 857 KECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAE 916
Query: 436 E-KESILE-TKQCVQKELESTKTD-LEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAI 492
K +LE KQ Q ++E + + EHR IE+ R L + + + S E +
Sbjct: 917 SYKNLLLEYEKQSEQLDVEKERANNFEHR---IEDLTRQLRNSTLQCETINS--DNEDLL 971
Query: 493 KDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFD-NLN 551
I + ++ +K T + E L
Sbjct: 972 ARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQ 1031
Query: 552 DVGNMINQQRDKLFELTKRQEEYDEKLQTK----ENEIKRLVESMTEQEHVLNKKEKEIK 607
+ + +L EL K+ + + + E +K L + +T + + + E+EIK
Sbjct: 1032 KQKKQLQKTMQEL-ELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIK 1090
Query: 608 MLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVLKCSLL 667
+ +K+E I L + ++ E + + L K KK L ++ + +L+ SL
Sbjct: 1091 IQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELA-DSKQAETDHLILQASLK 1149
Query: 668 GVVTQSR 674
G + S+
Sbjct: 1150 GELEASQ 1156
Score = 32.3 bits (70), Expect = 6.1
Identities = 28/122 (22%), Positives = 58/122 (47%), Gaps = 2/122 (1%)
Query: 373 SYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVR 432
+Y K I+++K+E+ +K E + +EE Q + + SE VK L
Sbjct: 25 NYVKEIENLKNELMAVRSKYSEDKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVKKLQE 84
Query: 433 ELDE-KESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEE-IDELKSKLSTEK 490
E+++ + E +QK+L++T + + T+++ + ++ I+ L+ +L K
Sbjct: 85 EIEKIRPGFEEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLK 144
Query: 491 AI 492
AI
Sbjct: 145 AI 146
>AB177860-1|BAD66838.1| 1715|Homo sapiens KIAA0216 splice variant 2
protein.
Length = 1715
Score = 50.0 bits (114), Expect = 3e-05
Identities = 58/346 (16%), Positives = 147/346 (42%), Gaps = 17/346 (4%)
Query: 275 MKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNK 334
+K +L + + ++VV LEA L+ S+ E ++ D + ++
Sbjct: 1174 LKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQL----RDLEAKVKD 1229
Query: 335 LTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKL-I 393
+ + + ++ + A+ +L+ S ++ +++ + + ++ +
Sbjct: 1230 QEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEV 1289
Query: 394 EIEKKYNDS---IEEKKTLQENIDDLRTDLLESELRV-KDLVRELDEKESILETKQCVQK 449
++E++Y D + EK+ L+ + L + + K L ++L +++L Q +
Sbjct: 1290 QLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLD 1349
Query: 450 ELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE-LKSKLSTEKAIKDIXXXXXXXXXXXXX 508
L+++ K EI + K L E +K++ + E I+D+
Sbjct: 1350 HLKNSAPS----KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTA 1405
Query: 509 XXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELT 568
+ +++++ EE N++ + + D+ IN + +L E
Sbjct: 1406 LEEQLSRLQREK-NEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQ-INDLQAQLEEAN 1463
Query: 569 KRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEE 614
K ++E EKLQ +++++ L +SM ++ +++++E +I+ L + E
Sbjct: 1464 KEKQELQEKLQALQSQVEFLEQSMVDKS-LVSRQEAKIRELETRLE 1508
Score = 35.9 bits (79), Expect = 0.49
Identities = 45/263 (17%), Positives = 106/263 (40%), Gaps = 14/263 (5%)
Query: 394 EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELES 453
E E K + K+ L+ + DL+ D ES+ ++ L ++ Q + EL+
Sbjct: 1068 EFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC----------QRLTAELQD 1117
Query: 454 TKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXX 513
TK LE ++ E ++ E+ + + EK ++
Sbjct: 1118 TKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQRE---KLQREKDMLLAEAFSL 1174
Query: 514 XXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEE 573
++ + + +++++L+ ++ + + D + + + Q RD ++ ++EE
Sbjct: 1175 KQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEAS-LAKVKKQLRDLEAKVKDQEEE 1233
Query: 574 YDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEA 633
DE+ T + + + E E + KE++ +E+ EE ++E++ E
Sbjct: 1234 LDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1293
Query: 634 DIDVIITLAKYKKSLTLVLEKMS 656
+ + + + K+ L L +S
Sbjct: 1294 EYEDKQKVLREKRELEGKLATLS 1316
Score = 35.5 bits (78), Expect = 0.65
Identities = 44/235 (18%), Positives = 94/235 (40%), Gaps = 20/235 (8%)
Query: 378 IKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEK 437
+K+ E A ++ K IE+ L IDD+ E ++ L RE +E
Sbjct: 1364 LKNQLEESEFTCAAAVKARKAMEVEIED---LHLQIDDIAKAKTALEEQLSRLQREKNEI 1420
Query: 438 ESILETKQCVQKEL----ESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIK 493
++ LE Q EL ++ +I + + L E +E EL+ KL ++
Sbjct: 1421 QNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQV 1480
Query: 494 DIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDV 553
+ +E++++ L + Q+ +L + L +
Sbjct: 1481 EFLEQSMVDKSLVSR-----------QEAKIRELETRLEFERTQVKRLESLAS--RLKEN 1527
Query: 554 GNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM 608
+ ++RD+ R++E +++LQ + + K + + +E ++K+ E++M
Sbjct: 1528 MEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEM 1582
>AB177858-1|BAD66836.1| 2046|Homo sapiens KIAA0216 splice variant 1
protein.
Length = 2046
Score = 50.0 bits (114), Expect = 3e-05
Identities = 58/346 (16%), Positives = 147/346 (42%), Gaps = 17/346 (4%)
Query: 275 MKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNK 334
+K +L + + ++VV LEA L+ S+ E ++ D + ++
Sbjct: 1490 LKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQL----RDLEAKVKD 1545
Query: 335 LTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKL-I 393
+ + + ++ + A+ +L+ S ++ +++ + + ++ +
Sbjct: 1546 QEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEV 1605
Query: 394 EIEKKYNDS---IEEKKTLQENIDDLRTDLLESELRV-KDLVRELDEKESILETKQCVQK 449
++E++Y D + EK+ L+ + L + + K L ++L +++L Q +
Sbjct: 1606 QLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLD 1665
Query: 450 ELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE-LKSKLSTEKAIKDIXXXXXXXXXXXXX 508
L+++ K EI + K L E +K++ + E I+D+
Sbjct: 1666 HLKNSAPS----KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTA 1721
Query: 509 XXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELT 568
+ +++++ EE N++ + + D+ IN + +L E
Sbjct: 1722 LEEQLSRLQREK-NEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQ-INDLQAQLEEAN 1779
Query: 569 KRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEE 614
K ++E EKLQ +++++ L +SM ++ +++++E +I+ L + E
Sbjct: 1780 KEKQELQEKLQALQSQVEFLEQSMVDKS-LVSRQEAKIRELETRLE 1824
Score = 35.9 bits (79), Expect = 0.49
Identities = 45/263 (17%), Positives = 106/263 (40%), Gaps = 14/263 (5%)
Query: 394 EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELES 453
E E K + K+ L+ + DL+ D ES+ ++ L ++ Q + EL+
Sbjct: 1384 EFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC----------QRLTAELQD 1433
Query: 454 TKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXX 513
TK LE ++ E ++ E+ + + EK ++
Sbjct: 1434 TKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQRE---KLQREKDMLLAEAFSL 1490
Query: 514 XXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEE 573
++ + + +++++L+ ++ + + D + + + Q RD ++ ++EE
Sbjct: 1491 KQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEAS-LAKVKKQLRDLEAKVKDQEEE 1549
Query: 574 YDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEA 633
DE+ T + + + E E + KE++ +E+ EE ++E++ E
Sbjct: 1550 LDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1609
Query: 634 DIDVIITLAKYKKSLTLVLEKMS 656
+ + + + K+ L L +S
Sbjct: 1610 EYEDKQKVLREKRELEGKLATLS 1632
Score = 35.5 bits (78), Expect = 0.65
Identities = 44/235 (18%), Positives = 94/235 (40%), Gaps = 20/235 (8%)
Query: 378 IKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEK 437
+K+ E A ++ K IE+ L IDD+ E ++ L RE +E
Sbjct: 1680 LKNQLEESEFTCAAAVKARKAMEVEIED---LHLQIDDIAKAKTALEEQLSRLQREKNEI 1736
Query: 438 ESILETKQCVQKEL----ESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIK 493
++ LE Q EL ++ +I + + L E +E EL+ KL ++
Sbjct: 1737 QNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQV 1796
Query: 494 DIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDV 553
+ +E++++ L + Q+ +L + L +
Sbjct: 1797 EFLEQSMVDKSLVSR-----------QEAKIRELETRLEFERTQVKRLESLAS--RLKEN 1843
Query: 554 GNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM 608
+ ++RD+ R++E +++LQ + + K + + +E ++K+ E++M
Sbjct: 1844 MEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEM 1898
>AB125644-1|BAF44475.1| 1843|Homo sapiens PKB/Akt-binding protein
protein.
Length = 1843
Score = 50.0 bits (114), Expect = 3e-05
Identities = 137/699 (19%), Positives = 269/699 (38%), Gaps = 55/699 (7%)
Query: 23 EQESITSESHKITKLKTVWQEKMVTF-----EKSKKELEDRQNQVMELYASLRNTHRKMK 77
EQE+ E KT+ K +TF EK +L++ ++ SL+ KM
Sbjct: 662 EQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMA 721
Query: 78 LLGQKVNLPSAEELHI---MNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLN 134
L + +E+ + + + K S ++ +L + +E+ L + K+
Sbjct: 722 QLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQ 781
Query: 135 IPNSLVD-KCE-ETLFKRKEIINW----FESLMSQEKGISTKT--LTMKIKEFNAENDLL 186
+ + L D + E +TL K E + E L + K + +T L K+ EN L
Sbjct: 782 LESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRL 841
Query: 187 KSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCA-LSDLNTQNAEMRKQIHS 245
+ + ++ L+E N I L K N+T++ ++ + SC L +L +N E+ K+
Sbjct: 842 RQQAE-IKDTTLEENNVKIGNLEKE-NKTLSKEIGIYKESCVRLKELEKENKELVKRATI 899
Query: 246 G---------DHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQL 296
D + K+RL E T+ R L
Sbjct: 900 DIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQS--TDDSRYKLL 957
Query: 297 EAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKL 356
E+ LE +S ++ +++Q+L + +++K N L+ +
Sbjct: 958 ESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMV 1017
Query: 357 QSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDL 416
QS + + ++ E+ +LIE+E+ EK+ L+ + L
Sbjct: 1018 QSSPPISGEDN-----KWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQL 1072
Query: 417 RTDLLESELRVKDLVRE---LDEKESILETK----QCVQKELESTKTDLEHRKTEIEEYK 469
T + ++ L R+ L E+ + L+T+ Q L S T L ++ ++ +
Sbjct: 1073 ETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQ 1132
Query: 470 RLLFEKGEEIDELKSKLST--EKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSY 527
L + E + + + L + + IKD +S K+
Sbjct: 1133 SSLENENESVIKEREDLKSLYDSLIKD-HEKLELLHERQASEYESLISKHGTLKSAHKNL 1191
Query: 528 YEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQE----EYDEKLQTKEN 583
E +L+++ QL + L D+ M+ +++K+ K E EY +KL + +
Sbjct: 1192 EVEHRDLEDRYNQLLK--QKGQLEDLEKMLKVEQEKMLLENKNHETVAAEY-KKLCGEND 1248
Query: 584 EIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIIT-LA 642
+ + ++ VL K +K L + + +KL+ + + +D+ T L
Sbjct: 1249 RLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQ-QLDITSTKLN 1307
Query: 643 KYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRT-LRKNM 680
+ L+ + + NR L + ++ Q+RT L +NM
Sbjct: 1308 NQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNM 1346
Score = 43.6 bits (98), Expect = 0.002
Identities = 90/480 (18%), Positives = 191/480 (39%), Gaps = 25/480 (5%)
Query: 187 KSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSG 246
K+ + +LR E ++ ++DC K E M ++L K L +L + R
Sbjct: 257 KAKIRRLRQELEEKTEQLLDC--KQELEQMEIEL--KRLQQENMNLLSDARSARMYRDEL 312
Query: 247 DHHRPYANR-NXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARS 305
D R A R + K R+ + + +E LE LE R+
Sbjct: 313 DALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRA 372
Query: 306 ES---WSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXX 362
S LE+ + D + K+ + +++N T LE +A + +S
Sbjct: 373 RSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMT-LE-MAQKQSMDESLHLG 430
Query: 363 XXXXXXXXSASYNKS-IKDMKHEMN-LNIAKLIEIE---KKYNDSIEEKKTLQENIDDLR 417
++ +++ K + HE+N L ++L+++E + ++EE +T ++++
Sbjct: 431 WELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNA 490
Query: 418 TDLLESELRVKDLVRELDEKES-ILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKG 476
+ +L+ E + L ++++ E+ I++ KQ +Q ++ DL K ++E+ L E
Sbjct: 491 SKILKMEKENQRLSKKVEILENEIVQEKQSLQ-NCQNLSKDLMKEKAQLEKTIETLRENS 549
Query: 477 EEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKN 536
E ++ + E + + +K +L ++
Sbjct: 550 ERQIKILEQ-ENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEF 608
Query: 537 QITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQE 596
+ Q+++ ++ + G + ++L L E+ +E LQ K +K E + E
Sbjct: 609 EKRQIKK--ELEHYKEKGERAEELENELHHL----EKENELLQKKITNLKITCEKIEALE 662
Query: 597 HVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMS 656
++ E+E + L + + N+ L + LE N + + L + +SL KM+
Sbjct: 663 QENSELERENRKLKKTLDSFKNLTFQLES-LEKENSQLDEENLELRRNVESLKCASMKMA 721
Score = 41.1 bits (92), Expect = 0.013
Identities = 122/662 (18%), Positives = 263/662 (39%), Gaps = 66/662 (9%)
Query: 1 MKQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQN 60
M +++LE + ++D L+E E + ++ H + + + ++K+ + LE Q
Sbjct: 362 MLEDQLEGTRARSDK-LHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQK 420
Query: 61 QVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEP--KALEH 118
Q M+ L ++ + P H +N +L+ +LL+L + K +E
Sbjct: 421 QSMDESLHLGWELEQISRTSELSEAPQKSLGHEVN--ELTSSRLLKLEMENQSLTKTVEE 478
Query: 119 --STLDNKVTFDVNKLLNIP------NSLVDKCEETLFKRKEII----NWFESLMSQ--- 163
+T+D+ V + +K+L + + V+ E + + K+ + N + LM +
Sbjct: 479 LRTTVDS-VEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQ 537
Query: 164 -EKGIST--KTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQL 220
EK I T + +IK EN+ L ++ LR + + K E L
Sbjct: 538 LEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEK---ENKILHE 594
Query: 221 RTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLS 280
KE S LS + + +++K++ +H++ R +++ +++
Sbjct: 595 SIKETSSKLSKIEFEKRQIKKEL---EHYKEKGER--AEELENELHHLEKENELLQKKIT 649
Query: 281 RAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXX---------XXXEDFDQE 331
LK E++ LE + E+ L++T+ ++ + E
Sbjct: 650 N----LKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLE 705
Query: 332 LNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKS-----------IKD 380
L + +S+K + + + L ++L+S AS+ K+ I++
Sbjct: 706 LRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIEN 765
Query: 381 MKHEMNLNIA--KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKE 438
+ + L + K+ ++E + D E +TLQ+N+++L+ E K+ + L+++
Sbjct: 766 QRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKE-NKSLEQET 824
Query: 439 SILE-TKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEK----AIK 493
S LE K+ ++KE + + E + T +EE + +E L ++ K +K
Sbjct: 825 SQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLK 884
Query: 494 DIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGA-FDNLND 552
++ S+ + +L+ +L + G + L
Sbjct: 885 ELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLH 944
Query: 553 VGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEK 612
+ R KL E +K + + L+ KE +I L + E + + +E+K + +
Sbjct: 945 DEQSTDDSRYKLLE-SKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKN 1003
Query: 613 EE 614
E
Sbjct: 1004 YE 1005
Score = 39.9 bits (89), Expect = 0.030
Identities = 62/296 (20%), Positives = 127/296 (42%), Gaps = 19/296 (6%)
Query: 375 NKSIKDMKHEMNLNIAKLIEIEKKYNDSIE-EKKTLQENIDDLRT-DLLESELRVKDLVR 432
+K + K ++ I L E ++ +E E + L + + LR + +E RVKD+ +
Sbjct: 528 SKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEK 587
Query: 433 ELDE-KESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
E ESI ET + K +E K + K E+E YK EKGE +EL+++L +
Sbjct: 588 ENKILHESIKETSSKLSK-IEFEKRQI---KKELEHYK----EKGERAEELENELHHLEK 639
Query: 492 IKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLN 551
++ E + + + L + KN QL ++
Sbjct: 640 ENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQL 699
Query: 552 DVGNM---INQQRDKLFELTKRQEEYDEK-LQTKENEIKRLVESMTEQEHVLNKKEKEIK 607
D N+ N + K + Q + + K L++++ ++K+ +E + + E +
Sbjct: 700 DEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQ 759
Query: 608 MLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVLK 663
L+ + + + + K++ + E+++ L ++L LE++ IS++ L+
Sbjct: 760 GLDIENQRLQKTLENSNKKIQ-QLESELQ---DLEMENQTLQKNLEELKISSKRLE 811
>X03740-1|CAA27380.1| 876|Homo sapiens protein ( Human skeletal
mRNA for myosin heavy chain light meromyosin region. ).
Length = 876
Score = 49.6 bits (113), Expect = 4e-05
Identities = 40/223 (17%), Positives = 97/223 (43%), Gaps = 5/223 (2%)
Query: 394 EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELES 453
++++K E LQ I+D + ++ + ++K+L ++E E +E ++ + + E
Sbjct: 16 QLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERTSRAKAEK 75
Query: 454 TKTDLEHRKTEI-EEYKRLLFEKGEEID-ELKSKLSTEKAIKDIXXXXXXXXXXXXXXXX 511
++DL EI E + + +I+ K + +K +D+
Sbjct: 76 LRSDLSRELEEISERLEEAVGATSTQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 135
Query: 512 XXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQ 571
Q+ + L+ + ++++ D+L +++ + L ++ +
Sbjct: 136 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKM--EIDDLASNMETVSKAKGNLEKMCRAL 193
Query: 572 EEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEI-KMLNEKE 613
E+ +++TKE E +RL+ +T Q L + + E + L+EK+
Sbjct: 194 EDQLSEIKTKEEEQQRLINDLTAQRARLQQNQVEYSRQLDEKD 236
Score = 46.4 bits (105), Expect = 3e-04
Identities = 66/388 (17%), Positives = 155/388 (39%), Gaps = 19/388 (4%)
Query: 283 EHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIK-- 340
+ +LK + L++ +E ++ L++ + E+ + E ++ K
Sbjct: 18 DEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERTSRAKAEKLR 77
Query: 341 -DNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKY 399
D + LE+I+ E+ A + K +D++ + A + KK+
Sbjct: 78 SDLSRELEEISERLEEAVGATSTQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKH 137
Query: 400 NDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLE 459
DS+ E L E ID+L+ + E ++ E+D+ S +ET + LE LE
Sbjct: 138 ADSVAE---LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALE 194
Query: 460 HRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXX 519
+ +EI+ + E+ I++L ++ + + +
Sbjct: 195 DQLSEIKTKEE---EQQRLINDLTAQRARLQQNQVEYSRQLDEKDTLETQLSRGKQAFTQ 251
Query: 520 RESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQ 579
+ ++K EE + K+ + + D + + ++++ EL + + + ++
Sbjct: 252 QIEELKRQLEEEIKAKSALAHALQSSRHD-CDLLREQYEEEQEAKAELQRAMSKANSEVA 310
Query: 580 TKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIIN-----LLHNKLELRNEAD 634
+ + TE+ L + +K++ + EEH+ +N L K L+NE +
Sbjct: 311 QWRTKYETDAIQRTEE---LEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVE 367
Query: 635 IDVIITLAKYKKSLTLVLEKMSISNRVL 662
D++I + + + + +K + +++L
Sbjct: 368 -DLMIDVERTNAACAALDKKQTNFDKIL 394
Score = 46.4 bits (105), Expect = 3e-04
Identities = 104/592 (17%), Positives = 219/592 (36%), Gaps = 44/592 (7%)
Query: 42 QEKMVTFEKSKKELEDRQNQVMELYASLRNTHR-KMKLLGQKV-NLPSAEELHIMNVAKL 99
+++ F+K +++LE+ Q A+LR H + LG+++ NL ++ + K
Sbjct: 106 KKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQ----KLEKE 161
Query: 100 SPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFES 159
E +++ + A T+ +K ++ K+ +L D+ E K +E
Sbjct: 162 KSEMKMEI----DDLASNMETV-SKAKGNLEKMC---RALEDQLSEIKTKEEEQQRLIND 213
Query: 160 LMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRK--NANETMA 217
L +Q + + ++ + E D L++ L + + F ++I ++ L + A +A
Sbjct: 214 LTAQRARLQQNQVEYS-RQLD-EKDTLETQLSRGKQAFTQQIEELKRQLEEEIKAKSALA 271
Query: 218 LQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKD 277
L++ C L +R+Q + R +
Sbjct: 272 HALQSSRHDCDL---------LREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQ 322
Query: 278 RLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQ 337
R E K +R+ E +E ++ SLE+T D ++ N
Sbjct: 323 RTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVER-TNAACA 381
Query: 338 SIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEK 397
++ T+ + I ++ S S + + +K+ ++ +L +++
Sbjct: 382 ALDKKQTNFDKILAEWKQKCEETHAVLESFQKESRSLSTELFKIKNAYEESLDQLETLKR 441
Query: 398 KYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTD 457
E K LQ+ I DL + E R+ +L + K+ + + K +Q LE +
Sbjct: 442 -------ENKNLQQEISDLTEQIAEGGKRIHELEK---IKKQVEQEKSELQAALEEAEAS 491
Query: 458 LEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXX 517
LEH + +I R+ E + E+ K++ + D
Sbjct: 492 LEHEEGKI---LRIQLEVNQVKSEVDRKIAEKDEEIDQMKRNHIRIEESMQSTLNAEIRS 548
Query: 518 XXRESQMKSYYE-ELMNLKNQITQLREFGAFD--NLNDVGNMINQQRDKLFELTKRQEEY 574
++K E +L ++ Q+ A D N + ++ + L + + QE+
Sbjct: 549 RNDAIRLKKKMEGDLNEMEIQLNHANRMAAEDLRNYQNTQAILKDTQLHLDDALRSQEDL 608
Query: 575 DEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNK 626
E+L E L + E L + E+ K+ ++ + + LLH +
Sbjct: 609 KEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQ 660
Score = 45.6 bits (103), Expect = 6e-04
Identities = 54/260 (20%), Positives = 112/260 (43%), Gaps = 15/260 (5%)
Query: 407 KTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIE 466
K QE+ D+ D + + ++K E+ +S +E +Q + +L+ +L+ R E+E
Sbjct: 1 KLAQESAMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELE 60
Query: 467 EYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKS 526
E + ++L+S LS E +++I + +
Sbjct: 61 EEIEAERTSRAKAEKLRSDLSRE--LEEISERLEEAVGATSTQIEMNKKREAEFQKMRRD 118
Query: 527 YYEELMNLKNQITQLREFGAFDNLNDVGNMI-NQQRDKLFELTKRQEEYDEKLQTKENEI 585
E + + LR+ A D++ ++G I N QR K +L K + E ++ + +
Sbjct: 119 LEEATLQHEATAATLRKKHA-DSVAELGEQIDNLQRVKQ-KLEKEKSEMKMEIDDLASNM 176
Query: 586 KRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIIN--------LLHNKLELRNEAD-ID 636
+ + ++ E + E ++ + KEEE +IN L N++E + D D
Sbjct: 177 ETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQQNQVEYSRQLDEKD 236
Query: 637 VIIT-LAKYKKSLTLVLEKM 655
+ T L++ K++ T +E++
Sbjct: 237 TLETQLSRGKQAFTQQIEEL 256
Score = 35.1 bits (77), Expect = 0.86
Identities = 58/353 (16%), Positives = 127/353 (35%), Gaps = 12/353 (3%)
Query: 144 EETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEIND 203
+E L K++ ++ +S + E+ + + L KIKE A + L+ ++ RT K
Sbjct: 18 DEKLKKKEFEMSGLQSKIEDEQALGMQ-LQKKIKELQARIEELEEEIEAERTSRAKAEKL 76
Query: 204 IIDCLRKNANETMALQLRTKELSCALSDLNTQNAE---MRKQIHSG--DHHRPYAN-RNX 257
D R+ + L+ S + + AE MR+ + H A R
Sbjct: 77 RSDLSRELEEISERLEEAVGATSTQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKK 136
Query: 258 XXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXX 317
+K +L + + ++K ++ + + +A+ + R +
Sbjct: 137 HADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQ 196
Query: 318 XXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKS 377
E+ + +N LT L+ + + ++ +
Sbjct: 197 LSEIKTKEEEQQRLINDLTAQ----RARLQQNQVEYSRQLDEKDTLETQLSRGKQAFTQQ 252
Query: 378 IKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEK 437
I+++K ++ I + S + L+E ++ + E + + E+ +
Sbjct: 253 IEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQW 312
Query: 438 ESILETKQCVQ-KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
+ ET + +ELE K L R + EE+ + K +++ K +L E
Sbjct: 313 RTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNE 365
Score = 33.9 bits (74), Expect = 2.0
Identities = 36/159 (22%), Positives = 73/159 (45%), Gaps = 15/159 (9%)
Query: 329 DQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLN 388
++ N L I++ LE +R K+ + N S+ + K ++ +
Sbjct: 616 ERRANLLQAEIEELRATLEQTERSR-KIAEQELLDASERVQLLHTQNTSLINTKKKLETD 674
Query: 389 IAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQ 448
I+ +I+ + D I+E + +E TD + + ++L +E D + K
Sbjct: 675 IS---QIQGEMEDIIKEARNAEEKAKKAITD---AAMMAEELKKEQDTSAHLERMK---- 724
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKG-EEIDELKSKL 486
K LE T DL+HR ++E ++L + G ++I +L++K+
Sbjct: 725 KNLEQTVKDLQHR---LDEAEQLALKGGKKQIQKLEAKV 760
>U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein.
Length = 3113
Score = 49.6 bits (113), Expect = 4e-05
Identities = 62/334 (18%), Positives = 130/334 (38%), Gaps = 25/334 (7%)
Query: 278 RLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQ 337
RL E ++K V + +L+ LE+A+ E E+ + +DQ K T
Sbjct: 300 RLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTA 359
Query: 338 SIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEK 397
+ ED++ R+ +S + + + + + I+++
Sbjct: 360 LEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKA 419
Query: 398 KYNDSIEEKK----TLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELES 453
+ +++ K LQ +D L + + E +++ ++L E + Q + EL
Sbjct: 420 RLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENEL-- 477
Query: 454 TKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXX 513
+ +E K E K +K E+ L+++L K IK
Sbjct: 478 -RRSMEEMKKENNLLKSHSEQKAREVCHLEAEL---KNIKQC-------LNQSQNFAEEM 526
Query: 514 XXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEE 573
+E+ ++ E++ +N +T + L + +QRD +L K++E
Sbjct: 527 KAKNTSQETMLRDLQEKINQQENSLT-------LEKLKLAVADLEKQRDCSQDLLKKREH 579
Query: 574 YDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK 607
+ E+L K ++ ++ +++ L KKE E+K
Sbjct: 580 HIEQLNDKLSKTEKESKALLSALE-LKKKEYELK 612
Score = 44.4 bits (100), Expect = 0.001
Identities = 143/660 (21%), Positives = 258/660 (39%), Gaps = 64/660 (9%)
Query: 30 ESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAE 89
ESH+ L + + EK++ L+ + V EL + K++ L + S
Sbjct: 1991 ESHQSECLHCIQVAEAEVKEKTEL-LQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLT 2049
Query: 90 ELHIMN-VAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCE---- 144
+ + N +A+L+ E+ L L E S D + +V+K L +LV+K E
Sbjct: 2050 KCELENQIAQLNKEKEL-LVKESESLQARLSESDYE-KLNVSKALEA--ALVEKGEFALR 2105
Query: 145 --ETLFKRKEIINWFESLMSQEKGISTKTLTM--KIKEFNAENDLLKSSLDQLRTEF-LK 199
T + ++ E L + + K L + K+KE END LK ++ L E +
Sbjct: 2106 LSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMS 2165
Query: 200 EIND---IIDCLRKNAN-ETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANR 255
E N I+D A ET+ Q+ S + +L+ K+ + +
Sbjct: 2166 EENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKE------NLTKQIQ 2219
Query: 256 NXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQ-LEAALEQARSESWSLERTV 314
S+++++ +AE Q+K + V+ L+ L++ +L
Sbjct: 2220 EKQGQLSELDKLLSSFKSLLEEK-EQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQ 2278
Query: 315 XXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASY 374
++E ++L SI+ LE A EK Q +
Sbjct: 2279 EIMKATEQSLDPPIEEE-HQLRNSIEKLRARLE----ADEKKQLCVLQQLKESEHHADLL 2333
Query: 375 NKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVREL 434
+++++ E+ + + +S E +TL+ I+ + L EL D+V
Sbjct: 2334 KGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLEL---DVVTIR 2390
Query: 435 DEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKD 494
EKE++ +QKE E ++LE + E +L EK +E ++K K ST +
Sbjct: 2391 SEKENLTNE---LQKEQERI-SELEIINSSFEN---ILQEKEQEKVQMKEKSSTAM---E 2440
Query: 495 IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVG 554
+ +E + S E L K Q+ Q L++
Sbjct: 2441 MLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQ--------GLDEAK 2492
Query: 555 NMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNK---KEKEIKMLNE 611
N + + L + E+ +KL+ K+ EI RL + +QE +++K E E ++ E
Sbjct: 2493 NNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKE 2552
Query: 612 KEEEHMNIINLLHNKLEL---RNEADIDVIITLAKYKKSLTLVLE-----KMSISNRVLK 663
+ E N+ L K+++ +N + D + L K+L LE KMS +V K
Sbjct: 2553 QNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNK 2612
Score = 42.3 bits (95), Expect = 0.006
Identities = 66/395 (16%), Positives = 149/395 (37%), Gaps = 6/395 (1%)
Query: 273 SIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQEL 332
S++ ++ +L T ++ L+ E+ + ++ LE + ++
Sbjct: 1953 SVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKT 2012
Query: 333 NKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKL 392
L D + L+D +EKLQS N+ I + E L + +
Sbjct: 2013 ELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQ-IAQLNKEKELLVKES 2071
Query: 393 IEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELE 452
++ + ++S EK + + ++ + E LR+ E+ + +E + + E
Sbjct: 2072 ESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADE 2131
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEID-ELK-SKLSTEKAIKDIXXXXXXXXXXXXXXX 510
+ + + E E L +K E ++ EL+ S+ + E I D
Sbjct: 2132 KKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIE 2191
Query: 511 XXXXXXXXXRESQMKSYYEELMNLKNQITQLR-EFGAFDNL-NDVGNMINQQRDKLFELT 568
E + + E NL QI + + + D L + +++ ++ ++
Sbjct: 2192 EMARSLKVF-ELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIK 2250
Query: 569 KRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
+ + E LQ + E+ V ++ + ++ E+ + E+E + N I L +LE
Sbjct: 2251 EESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLE 2310
Query: 629 LRNEADIDVIITLAKYKKSLTLVLEKMSISNRVLK 663
+ + V+ L + + L+ ++ R L+
Sbjct: 2311 ADEKKQLCVLQQLKESEHHADLLKGRVENLERELE 2345
Score = 41.9 bits (94), Expect = 0.007
Identities = 88/491 (17%), Positives = 191/491 (38%), Gaps = 30/491 (6%)
Query: 163 QEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRT 222
+++ ++L ++KE +++ L + L + E E+ I+ L+K E L +
Sbjct: 1790 EDRDRKVESLLNEMKELDSKLHLQEVQL-MTKIEACIELEKIVGELKK---ENSDLSEKL 1845
Query: 223 KELSCALSDLNTQNAEMRKQIHSG-DHHRPYANRNXXXXXXXXXXXXXXXXSI-MKDRLS 280
+ SC +L Q E + ++S + H ++R + +++ LS
Sbjct: 1846 EYFSCDHQEL-LQRVETSEGLNSDLEMHADKSSREDIGDNVAKVNDSWKERFLDVENELS 1904
Query: 281 RAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIK 340
R + + + LEA LE ++E LE+ E+ ++ Q ++
Sbjct: 1905 RIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQ-LR 1963
Query: 341 DNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYN 400
+ A ++L + I+ + E+ L + +
Sbjct: 1964 GELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVS 2023
Query: 401 DSIEEKKTLQENIDDLRTD---LLESELRVKDLVRELD-EKESILETKQCVQKELESTKT 456
+ +++K LQE + L D L ++ +++ + +L+ EKE +++ + +Q L +
Sbjct: 2024 ELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDY 2083
Query: 457 D-------LEHRKTEIEEYKRLLFEKGEEIDELK---SKLSTE---KAIKDIXXXXXXXX 503
+ LE E E+ L EE+ +L+ KL K +
Sbjct: 2084 EKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKE 2143
Query: 504 XXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDK 563
RE QM +EL+ L + ++ + ++ +
Sbjct: 2144 RERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELD 2203
Query: 564 LFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEK-EIKMLNEKEEEHMNIINL 622
L L +E +++Q K+ ++ L + ++ + +L +KE+ EI++ +EE + +
Sbjct: 2204 LVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQI----KEESKTAVEM 2259
Query: 623 LHNKLELRNEA 633
L N+L+ NEA
Sbjct: 2260 LQNQLKELNEA 2270
Score = 40.7 bits (91), Expect = 0.017
Identities = 92/479 (19%), Positives = 192/479 (40%), Gaps = 34/479 (7%)
Query: 28 TSESHKITKLKTVWQEKMVTFEKSKKELEDR-QNQVMELYASLRNTHRKMKLLGQKVNLP 86
+S H + +LK QE ELE R Q E+ + N ++++L +K +
Sbjct: 274 SSSPHLLDQLKAQNQE----LRNKINELELRLQGHEKEMKGQV-NKFQELQLQLEKAKVE 328
Query: 87 SAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKL-LNIPNSLVDKCE- 144
E+ ++N + ++L++ A + + +++ L+ K+ L N+ +C
Sbjct: 329 LIEKEKVLNKCR---DELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSL 385
Query: 145 ETLFKRKEIINWFESLMSQEKGIST---------KTLTMKIKEFNAENDLLKSSLDQLRT 195
E K KE + E L Q++ T LT ++++ +++L++ LD+L +
Sbjct: 386 EQKIKEKEK-EFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTS 444
Query: 196 EFLKEINDIIDCLRKNANETMALQ---LRTKELSCALSDLNTQNAEMRKQIHSGDHHRPY 252
+ N++ + +K A Q ++ EL ++ ++ +N ++ HS R
Sbjct: 445 VKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKS--HSEQKAREV 502
Query: 253 ANRNXXXXXXXX-XXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAAL--EQARSESWS 309
+ MK + + E L+ E++ Q E +L E+ +
Sbjct: 503 CHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVAD 562
Query: 310 LERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXX 369
LE+ +Q +KL+++ K++ L AL +K +
Sbjct: 563 LEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLS--ALELKKKEYELKEEKTLFSC 620
Query: 370 XSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKD 429
+ K + M+ E +K+ +E + E + L D + +++
Sbjct: 621 WKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRN 680
Query: 430 LVRELDEKESILETKQCVQKELESTK--TDLEHRKTEIEEYKRLLFEKGEEIDELKSKL 486
L LD K +ET++ EL+ +D +H+K EIE + ++++L+ KL
Sbjct: 681 LHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQK-EIENMCLKTSQLTGQVEDLEHKL 738
Score = 39.5 bits (88), Expect = 0.040
Identities = 98/488 (20%), Positives = 188/488 (38%), Gaps = 51/488 (10%)
Query: 19 EDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKL 78
E ++E E I S I + K QEK+ EKS +E Q Q+ EL + H +
Sbjct: 2405 ERISELEIINSSFENILQEKE--QEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEA 2462
Query: 79 LGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNS 138
K S++ + +L QLLQ G + + L + V + ++ +
Sbjct: 2463 CKAKEQNLSSQ----VECLELEKAQLLQ---GLDEAKNNYIVLQSSVNGLIQEVEDGKQK 2515
Query: 139 LVDKCEETLFKRKEIINWFE--SLMSQEKGIST--KTLTMKIKEFNAENDLLKSSLDQLR 194
L K EE + +I + + S +SQ +G K ++++ E + K + Q +
Sbjct: 2516 LEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQ-KIQVLQSK 2574
Query: 195 TEFLKEINDIIDCLRKNA-NETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYA 253
L++ +++ KN NE ++ ++ + + E+++++H
Sbjct: 2575 NASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHE----MAQK 2630
Query: 254 NRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERT 313
++ + + ++ QLK +L+ +L+ + E
Sbjct: 2631 TAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGK 2690
Query: 314 VXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSAS 373
V + +++ L + N + +I REKL S
Sbjct: 2691 VREEIAEYQLRLHEAEKKHQALL--LDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDL- 2747
Query: 374 YNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQEN---IDDLRTDLLESELRVKDL 430
+K K E+N ++ +I + E KKT +N ++ L+ + ++ ++K L
Sbjct: 2748 ----LKSSKEELNNSLKATTQILE------ELKKTKMDNLKYVNQLKKENERAQGKMKLL 2797
Query: 431 VRELDEKESILETKQCVQKELESTKTDLEHRK-------------TEIEEYKRLLFEKGE 477
++ + E E K+ +QKEL + E +K TEI+E K L EK +
Sbjct: 2798 IKSCKQLE---EEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTK 2854
Query: 478 EIDELKSK 485
E DE K
Sbjct: 2855 EADEYLDK 2862
Score = 39.1 bits (87), Expect = 0.053
Identities = 68/316 (21%), Positives = 118/316 (37%), Gaps = 17/316 (5%)
Query: 277 DRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLT 336
D+L+ + QL+ N+E Q EQA S E + +
Sbjct: 440 DKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKA 499
Query: 337 QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSA---SYNKSIKDMKHEMNLNIAKLI 393
+ + L++I + Q+ + I ++ + L KL
Sbjct: 500 REVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLA 559
Query: 394 --EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKEL 451
++EK+ + S + K + +I+ L L ++E K L+ L+ K+ E K+ +K L
Sbjct: 560 VADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYELKE--EKTL 617
Query: 452 EST-KTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXX 510
S K++ E T++E K L K I+ L++ L T++ IK
Sbjct: 618 FSCWKSENEKLLTQMESEKENLQSK---INHLETCLKTQQ-IKSHEYNERVRTLEMDREN 673
Query: 511 XXXXXXXXXRESQMKSYYEELMNLKN-QITQLREFGAFDNLNDVGNMINQQRDKLFELTK 569
KS E L ++ Q EF + ++ NM K +LT
Sbjct: 674 LSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCL----KTSQLTG 729
Query: 570 RQEEYDEKLQTKENEI 585
+ E+ + KLQ NEI
Sbjct: 730 QVEDLEHKLQLLSNEI 745
Score = 36.7 bits (81), Expect = 0.28
Identities = 98/486 (20%), Positives = 181/486 (37%), Gaps = 61/486 (12%)
Query: 10 QNQTDGCLYEDLNEQESITSE-SHKITKLKTVWQEKMV-TFEKSKKELED---RQNQVME 64
Q Q + L + E I E + K + + Q + T ++ K ED QN V E
Sbjct: 841 QKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAE 900
Query: 65 LYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNK 124
++L N ++++LL KV AE + L + L +L E +LE + +
Sbjct: 901 TLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSI 960
Query: 125 VTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAEND 184
++ + ++ E L + + + ++QEK L K + F D
Sbjct: 961 ISLNKREI------------EELTQENGTLKEINASLNQEK----MNLIQKSESFANYID 1004
Query: 185 LLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIH 244
+ S+ +L ++ +E ++ + N L + K A + N++ + +
Sbjct: 1005 EREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYK----AAQEKNSKLECLLNECT 1060
Query: 245 SGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQAR 304
S NR + K L+ AE + N +++LE + R
Sbjct: 1061 S-----LCENRKNELEQLKEAFAKEHQEFLTK--LAFAEER---NQNLMLELETVQQALR 1110
Query: 305 SESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXX 364
SE + +E NK+ + + D + E+L
Sbjct: 1111 SEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVND-------LLQENEQLMKVMKTKH 1163
Query: 365 XXXXXXSASYNKSIKDMKHEMN-LNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDL--L 421
S S+K+ + E N N +++E K + ++D L L
Sbjct: 1164 ECQNLESEPIRNSVKERESERNQCNFKPQMDLEVK-----------EISLDSYNAQLVQL 1212
Query: 422 ESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE 481
E+ LR K+L + EKE K+C+Q EL++ + DLE + + + + K EID
Sbjct: 1213 EAMLRNKELKLQESEKE-----KECLQHELQTIRGDLETSNLQDMQSQEISGLKDCEIDA 1267
Query: 482 LKSKLS 487
+ +S
Sbjct: 1268 EEKYIS 1273
Score = 36.7 bits (81), Expect = 0.28
Identities = 75/451 (16%), Positives = 164/451 (36%), Gaps = 15/451 (3%)
Query: 170 KTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCAL 229
+ LT +I+E + L L ++ ++ I ++ LQ + KEL+ A+
Sbjct: 2212 ENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAV 2271
Query: 230 SDLNTQNAEMRKQIHSGDH--HRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLK 287
+ L M+ S D + RN + +L +EH
Sbjct: 2272 AALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHAD 2331
Query: 288 TNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLE 347
RV LE LE AR+ + E ++ +TQS++ +
Sbjct: 2332 LLKGRVENLERELEIARTN----QEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVV 2387
Query: 348 DIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEK- 406
I +E L + N S +++ E ++ E + ++ +
Sbjct: 2388 TIRSEKENLTNELQKEQERISELEI-INSSFENILQEKEQEKVQMKEKSSTAMEMLQTQL 2446
Query: 407 KTLQENIDDLRTDLLESELRVKDLVRELD----EKESILETKQCVQKELESTKTDLEHRK 462
K L E + L D + + ++L +++ EK +L+ + ++ +
Sbjct: 2447 KELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLI 2506
Query: 463 TEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRES 522
E+E+ K+ L +K EEI LK+++ ++ + E
Sbjct: 2507 QEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQ 2566
Query: 523 QMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKE 582
+++ + +L++ + L+ ++ NL + + + E + + +LQ +
Sbjct: 2567 KIQVLQSKNASLQDTLEVLQ--SSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREM 2624
Query: 583 NEI-KRLVESMTEQEHVLNKKEKEIKMLNEK 612
+E+ ++ E E N+ E+++L E+
Sbjct: 2625 HEMAQKTAELQEELSGEKNRLAGELQLLLEE 2655
Score = 31.9 bits (69), Expect = 8.0
Identities = 48/257 (18%), Positives = 103/257 (40%), Gaps = 20/257 (7%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLES-ELRVKDLVRELDEKESILET--KQCV 447
K +E+K E+ ++N + R L + + + K+ EL ++ +T ++C+
Sbjct: 356 KYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECI 415
Query: 448 Q------KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS-TEKAIK--DIXXX 498
Q +EL+ K + E+++ + + ++E K KL E+A + I
Sbjct: 416 QMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKEN 475
Query: 499 XXXXXXXXXXXXXXXXXXXXXRESQMKSYYE-ELMNLKNQITQLREFGAFDNLNDVGN-- 555
++++ + E EL N+K + Q + F +
Sbjct: 476 ELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQET 535
Query: 556 MINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEE 615
M+ ++K+ Q+E L+ + + L + + +L K+E I+ LN+K +
Sbjct: 536 MLRDLQEKI-----NQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSK 590
Query: 616 HMNIINLLHNKLELRNE 632
L + LEL+ +
Sbjct: 591 TEKESKALLSALELKKK 607
>X69292-1|CAA49154.1| 881|Homo sapiens smooth muscle mysosin heavy
chain protein.
Length = 881
Score = 49.2 bits (112), Expect = 5e-05
Identities = 112/611 (18%), Positives = 235/611 (38%), Gaps = 37/611 (6%)
Query: 24 QESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQN---QVMELYASLRNTHRKMKLLG 80
QE + + TKL+ + +E+ ++ +E+E +QN + L L ++ +K++
Sbjct: 234 QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFA 293
Query: 81 QKVN-LPSAE---ELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIP 136
V L + + I N+ + E+ + K LD+ V D++ +
Sbjct: 294 STVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV-DLDNQRQLV 352
Query: 137 NSLVD---KCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQL 193
++L K ++ L + K I + + + + + + T + A + L++ +
Sbjct: 353 SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELE 412
Query: 194 RT-EFLK-EINDII---DCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDH 248
RT + LK E+ D++ D + KN +E L+ + L + ++ TQ E+ ++ + +
Sbjct: 413 RTNKMLKAEMEDLVSSKDDVGKNVHE---LEKSKRALETQMEEMKTQLEELEDELQATED 469
Query: 249 H--RPYANRNXXXXXXXXXXXXXXXXSIMKDR-LSRAEHQLKTNVERVVQLEAALEQARS 305
R N + K R L R H+ +T +E + A A+
Sbjct: 470 AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK 529
Query: 306 ESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXX 365
+ + + E+ ++L KL +KD LED +R+++ +
Sbjct: 530 KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK 589
Query: 366 XXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESEL 425
A + +D+ K ++EK+ + EE + + L+ + E
Sbjct: 590 KAKSLEADLMQLQEDLAAAERAR--KQADLEKE--ELAEELASSLSGRNALQDEKRRLEA 645
Query: 426 RVKDLVRELDEKESILET------KQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI 479
R+ L EL+E++ +E K Q E S + E + E R E+ +
Sbjct: 646 RIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESSRQQLERQNK- 704
Query: 480 DELKSKL-STEKAIKD-IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQ 537
EL+SKL E A+K +++ KS ++ LK
Sbjct: 705 -ELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEI 763
Query: 538 ITQLR-EFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQE 596
+ Q+ E + + N + +L + EE +++ +++R ++ TE
Sbjct: 764 LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESN 823
Query: 597 HVLNKKEKEIK 607
+ ++ +K
Sbjct: 824 EAMGREVNALK 834
Score = 48.8 bits (111), Expect = 7e-05
Identities = 84/432 (19%), Positives = 167/432 (38%), Gaps = 44/432 (10%)
Query: 286 LKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELN-KLTQSIKDNTT 344
LKT +E + A ++ R++ + E QE+ K Q++++ T
Sbjct: 60 LKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTE 119
Query: 345 HLEDIALAREKLQSXXXXXXXXXXXXSASYN---KSIKDMKHEMNLNIAKLIEIEKKYND 401
LE A+ L + ++ ++++H+ A++ E++ K +D
Sbjct: 120 QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 179
Query: 402 SIEEKKTLQENIDDLRTD-------LLESELRVKDLVRELDEKESILETKQCVQKELEST 454
+ L + + L+ + L E+E + L +++ S L+ Q + +E
Sbjct: 180 GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQ 239
Query: 455 KTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXX 514
K ++ + ++EE + L ++ +E E+++K + E+ I +
Sbjct: 240 KLNVSTKLRQLEEERNSLQDQLDE--EMEAKQNLERHISTLNIQLSDSKKKLQDFASTVE 297
Query: 515 XXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLF--------- 565
E K + +E+ NL Q + + A+D L N + Q+ D L
Sbjct: 298 AL----EEGKKRFQKEIENLTQQYEE--KAAAYDKLEKTKNRLQQELDDLVVDLDNQRQL 351
Query: 566 --ELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLN---------EKEE 614
L K+Q ++D+ L ++N + + E +EKE K L+ E +E
Sbjct: 352 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAE--AEAREKETKALSLARALEEALEAKE 409
Query: 615 EHMNIINLLHNKLELRNEADIDV---IITLAKYKKSLTLVLEKMSISNRVLKCSLLGVVT 671
E +L ++E + DV + L K K++L +E+M L+ L
Sbjct: 410 ELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED 469
Query: 672 QSRTLRKNMSGL 683
L NM L
Sbjct: 470 AKLRLEVNMQAL 481
Score = 47.6 bits (108), Expect = 2e-04
Identities = 77/367 (20%), Positives = 152/367 (41%), Gaps = 38/367 (10%)
Query: 161 MSQEKGISTKTLTMKIKEFN---AENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMA 217
M Q+ + + LT ++++F A D K +L++ + E+ + ++ ++
Sbjct: 106 MRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKK 165
Query: 218 LQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYAN---RNXXXXXXXXXXXXXXXXSI 274
L+ + +EL SD AE+ ++H + S
Sbjct: 166 LEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQ 225
Query: 275 MKD--RLSRAEHQLKTNVE-RVVQLEA-------ALEQARSESWSLER---TVXXXXXXX 321
++D L + E + K NV ++ QLE L++ +LER T+
Sbjct: 226 LQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDS 285
Query: 322 XXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDM 381
+DF + L + K +E++ E+ + + + D+
Sbjct: 286 KKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDL 345
Query: 382 KHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKD-----LVRELDE 436
++ L ++ L + ++K++ + E+K + D R D E+E R K+ L R L+E
Sbjct: 346 DNQRQL-VSNLEKKQRKFDQLLAEEKNISSKYADER-DRAEAEAREKETKALSLARALEE 403
Query: 437 ----KESILETKQCVQKELE---STKTDLEHRKTEIEEYKRLLFEKGEE----IDELKSK 485
KE + T + ++ E+E S+K D+ E+E+ KR L + EE ++EL+ +
Sbjct: 404 ALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDE 463
Query: 486 L-STEKA 491
L +TE A
Sbjct: 464 LQATEDA 470
Score = 46.8 bits (106), Expect = 3e-04
Identities = 102/604 (16%), Positives = 231/604 (38%), Gaps = 31/604 (5%)
Query: 20 DLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLL 79
D N+Q + +L+ + Q K E KK+LE QV EL + + R L
Sbjct: 132 DKNKQTLEKENADLAGELRVLGQAKQEV-EHKKKKLEA---QVQELQSKCSDGERARAEL 187
Query: 80 GQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSL 139
KV+ E + + + + ++L + + + + + LN+ L
Sbjct: 188 NDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKL 247
Query: 140 VDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLK-SSLDQLRTEFL 198
EE + ++ E+ + E+ IST + + + ++ +L++ + F
Sbjct: 248 RQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ 307
Query: 199 KEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXX 258
KEI ++ + A L+ L L DL R+ + + + + ++
Sbjct: 308 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQ--- 364
Query: 259 XXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERT---VX 315
S D RAE + + + + L ALE+A LERT +
Sbjct: 365 -----LLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLK 419
Query: 316 XXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYN 375
+D + +++L +S + T +E++ E+L+ +
Sbjct: 420 AEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ 479
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD 435
+ ++ + E ++ + E +T E+ R ++ +++ +++L+
Sbjct: 480 ALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLE 539
Query: 436 -EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRL---LFEKGEEIDELKSKLSTE-K 490
+ +S ++ ++ K+L + ++ + E+E+ + +F +E ++ L +
Sbjct: 540 LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLM 599
Query: 491 AIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNL 550
+++ S + +E L+ +I QL E +
Sbjct: 600 QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEE----ELE 655
Query: 551 NDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK-ML 609
+ GNM D++ + T++ E+ +L T+ + ++ ES +Q L ++ KE++ L
Sbjct: 656 EEQGNM-EAMSDRVRKATQQAEQLSNELATERSTAQK-NESSRQQ---LERQNKELRSKL 710
Query: 610 NEKE 613
+E E
Sbjct: 711 HEME 714
Score = 44.4 bits (100), Expect = 0.001
Identities = 126/646 (19%), Positives = 242/646 (37%), Gaps = 67/646 (10%)
Query: 4 EELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQ-V 62
EELE + + + L +QE ++T LK E+ + E +E+ + Q V
Sbjct: 55 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 114
Query: 63 MELYASLRNTHR------KMKLLGQKVNLPSAEELHIMNVAKLSPE----QLLQLCAGGE 112
EL L R K K +K N A EL ++ AK E +L +
Sbjct: 115 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ 174
Query: 113 PKALEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTL 172
K + ++ V+KL N S+ E K ++ SL SQ + T+ L
Sbjct: 175 SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQ--DTQEL 232
Query: 173 TMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDL 232
++E + + + L QL +E N + D L + L+ L+ LSD
Sbjct: 233 ---LQEETRQKLNVSTKLRQLE----EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDS 285
Query: 233 NTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVER 292
+ + + + + + + D+L + +++L+ ++
Sbjct: 286 KKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAY-----DKLEKTKNRLQQELDD 340
Query: 293 VVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQ---ELNKLTQSIKDNTTHLEDI 349
+V L+ R +LE+ FDQ E ++ D E
Sbjct: 341 LV---VDLDNQRQLVSNLEK-----------KQRKFDQLLAEEKNISSKYADERDRAEAE 386
Query: 350 ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTL 409
A +E ++ K +K EM ++ ++ K ++ + K+ L
Sbjct: 387 AREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL 446
Query: 410 QENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYK 469
+ +++++T L E E +L D K + Q ++ + E DL+ R + EE +
Sbjct: 447 ETQMEEMKTQLEELE---DELQATEDAKLRLEVNMQALKGQFE---RDLQARDEQNEEKR 500
Query: 470 RLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYE 529
R L ++ E +++L E+ + + +S +K E
Sbjct: 501 RQL---QRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQA------DSAIKGREE 551
Query: 530 ELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLV 589
+ L+ Q+++F L D RD++F K E ++K ++ E ++ +L
Sbjct: 552 AIKQLRKLQAQMKDFQR--ELEDA----RASRDEIFATAK---ENEKKAKSLEADLMQLQ 602
Query: 590 ESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADI 635
E + E + + E + L E+ ++ N L ++ + R EA I
Sbjct: 603 EDLAAAERARKQADLEKEELAEELASSLSGRNALQDE-KRRLEARI 647
Score = 35.5 bits (78), Expect = 0.65
Identities = 52/222 (23%), Positives = 99/222 (44%), Gaps = 25/222 (11%)
Query: 394 EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELES 453
EI +K N+++++ + L+ +I DL+ DL +SE ++ EK+ K+ + +ELE+
Sbjct: 11 EIAQK-NNALKKIRELEGHISDLQEDL-DSERAARNKA----EKQ-----KRDLGEELEA 59
Query: 454 TKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXX 513
KT+LE + L ++ +E+ LK L E +
Sbjct: 60 LKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELT- 118
Query: 514 XXXXXXRESQMKSYYEELMNL-KNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQE 572
Q++ + NL KN+ T +E +L ++ Q + ++ K+ E
Sbjct: 119 --------EQLEQFKRAKANLDKNKQTLEKENA---DLAGELRVLGQAKQEVEHKKKKLE 167
Query: 573 EYDEKLQTKENEIKRLVESMTEQEHVL-NKKEKEIKMLNEKE 613
++LQ+K ++ +R + ++ H L N+ E MLNE E
Sbjct: 168 AQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAE 209
>BC114545-1|AAI14546.1| 1939|Homo sapiens myosin, heavy chain 1,
skeletal muscle, adult protein.
Length = 1939
Score = 49.2 bits (112), Expect = 5e-05
Identities = 75/477 (15%), Positives = 186/477 (38%), Gaps = 26/477 (5%)
Query: 148 FKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDC 207
FK K ++ +S ++++ + K K KE A+ + + L++ ++E ND+
Sbjct: 838 FKIKPLL---KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQ 894
Query: 208 LRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPY--ANRNXXXXXXXXX 265
++ A+ + R +L L + E+ ++ + A +
Sbjct: 895 VQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSEL 954
Query: 266 XXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXX 325
+ ++ + +H + V+ + + A L++ ++ ++ +
Sbjct: 955 KKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDL 1014
Query: 326 EDFDQELNKLTQS---IKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMK 382
+ + ++N LT++ ++ LE +K++ +S D++
Sbjct: 1015 QAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIE 1074
Query: 383 HEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILE 442
++ ++++K E LQ I+D + ++ + ++K+L ++E E +E
Sbjct: 1075 NDKQ-------QLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIE 1127
Query: 443 TKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEID---ELKSKLSTE--KAIKDIXX 497
++ + + E ++DL E+EE L E G E+ K E K +D+
Sbjct: 1128 AERASRAKAEKQRSDLSR---ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEE 1184
Query: 498 XXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMI 557
Q+ + L+ + ++++ D+L +
Sbjct: 1185 ATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKM--EIDDLASNMETV 1242
Query: 558 NQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEI-KMLNEKE 613
++ + L ++ + E+ +++TKE E +RL+ +T Q L + E + L+EK+
Sbjct: 1243 SKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKD 1299
Score = 46.8 bits (106), Expect = 3e-04
Identities = 73/381 (19%), Positives = 163/381 (42%), Gaps = 26/381 (6%)
Query: 277 DRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLT 336
D+L + + QL+ ++ V + E+ +E + +R + +D + L K+
Sbjct: 910 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 969
Query: 337 QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHE---MNLNIAKLI 393
+ ++++ L ++ +++ D++ E +N I
Sbjct: 970 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKI 1029
Query: 394 EIEKKYND---SIEEKKTLQENID----DLRTDLL---ESELRVKDLVRELDEKESILET 443
++E++ +D S+E++K ++ +++ L DL ES + +++ ++LDEK E
Sbjct: 1030 KLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEF 1089
Query: 444 KQC-VQKELESTKTDLEHRKTEIEEYKRLLFEKGEEID-ELKSKLSTEKAIKDIXXXXXX 501
+ +Q ++E + + +I+E + + E EEI+ E S+ EK D+
Sbjct: 1090 EMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEE 1149
Query: 502 XXXXXXXXXXXXXXXXXX---RESQMKSYYEEL--MNLKNQITQ--LREFGAFDNLNDVG 554
RE++ + +L L+++ T LR+ A D++ ++G
Sbjct: 1150 ISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHA-DSVAELG 1208
Query: 555 NMI-NQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKE 613
I N QR K +L K + E ++ + ++ + ++ E + E ++ + KE
Sbjct: 1209 EQIDNLQRVKQ-KLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKE 1267
Query: 614 EEHMNIIN-LLHNKLELRNEA 633
EE +IN L + L+ E+
Sbjct: 1268 EEQQRLINDLTAQRARLQTES 1288
Score = 44.0 bits (99), Expect = 0.002
Identities = 103/590 (17%), Positives = 217/590 (36%), Gaps = 40/590 (6%)
Query: 42 QEKMVTFEKSKKELEDRQNQVMELYASLRNTHR-KMKLLGQKV-NLPSAEELHIMNVAKL 99
+++ F+K +++LE+ Q A+LR H + LG+++ NL ++ + K
Sbjct: 1169 KKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQ----KLEKE 1224
Query: 100 SPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFES 159
E +++ + A T+ +K ++ K+ +L D+ E K +E
Sbjct: 1225 KSEMKMEI----DDLASNMETV-SKAKGNLEKMCR---ALEDQLSEIKTKEEEQQRLIND 1276
Query: 160 LMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKN--ANETMA 217
L +Q + T++ ++ + E D L S L + + F ++I ++ L + A +A
Sbjct: 1277 LTAQRARLQTESGEYS-RQLD-EKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALA 1334
Query: 218 LQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKD 277
L++ C L +R+Q + R +
Sbjct: 1335 HALQSSRHDCDL---------LREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQ 1385
Query: 278 RLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQ 337
R E K +R+ E +E ++ SLE+T D ++ N
Sbjct: 1386 RTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERT-NAACA 1444
Query: 338 SIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEK 397
++ + + I ++ S S + + +K+ ++ +L +++
Sbjct: 1445 ALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKR 1504
Query: 398 KYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTD 457
E K LQ+ I DL + E R+ +L + K+ + + K +Q LE +
Sbjct: 1505 -------ENKNLQQEISDLTEQIAEGGKRIHELKKI---KKQVEQEKSELQAALEEAEAS 1554
Query: 458 LEHRKTEIEEYKRLLFEKGEEID-ELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXX 516
LEH + +I + L + E+D ++ K +K
Sbjct: 1555 LEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRND 1614
Query: 517 XXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDE 576
+ +M+ E+ N ++ A N + ++ + L + + QE+ E
Sbjct: 1615 AIRLKKKMEGDLNEMEIQLNHANRMAA-EALRNYRNTQAILKDTQLHLDDALRSQEDLKE 1673
Query: 577 KLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNK 626
+L E L + E L + E+ K+ ++ + + LLH +
Sbjct: 1674 QLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQ 1723
Score = 34.3 bits (75), Expect = 1.5
Identities = 87/472 (18%), Positives = 175/472 (37%), Gaps = 27/472 (5%)
Query: 37 LKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKV--NLPSAEE-LHI 93
L V +EK T E K L + + E A L + ++ Q+ +L + E+ ++
Sbjct: 965 LAKVEKEKHAT-ENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNT 1023
Query: 94 MNVAKLSPEQLLQLCAGG---EPKA---LEHST--LDNKVTFDVNKLLNIPNSLVDKCEE 145
+ AK+ EQ + G E K LE + L+ + ++I N + +E
Sbjct: 1024 LTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDK-QQLDE 1082
Query: 146 TLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDII 205
L K++ ++ +S + E+ + + L KIKE A + L+ ++ R K
Sbjct: 1083 KLKKKEFEMSGLQSKIEDEQALGMQ-LQKKIKELQARIEELEEEIEAERASRAKAEKQRS 1141
Query: 206 DCLRKNANETMALQLRTKELSCALSDLNTQNAE---MRKQIHSG--DHHRPYAN-RNXXX 259
D R+ + L+ S + + AE MR+ + H A R
Sbjct: 1142 DLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHA 1201
Query: 260 XXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXX 319
+K +L + + ++K ++ + + +A+ + R +
Sbjct: 1202 DSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLS 1261
Query: 320 XXXXXXEDFDQELNKLT-QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSI 378
E+ + +N LT Q + T E EK ++ + I
Sbjct: 1262 EIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEK-----DTLVSQLSRGKQAFTQQI 1316
Query: 379 KDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKE 438
+++K ++ I + S + L+E ++ + E + + E+ +
Sbjct: 1317 EELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWR 1376
Query: 439 SILETKQCVQ-KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
+ ET + +ELE K L R + EE+ + K +++ K +L E
Sbjct: 1377 TKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNE 1428
Score = 33.1 bits (72), Expect = 3.5
Identities = 32/139 (23%), Positives = 59/139 (42%), Gaps = 11/139 (7%)
Query: 329 DQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLN 388
++ N L I++ LE +R K+ + N S+ + K ++ +
Sbjct: 1679 ERRANLLQAEIEELRATLEQTERSR-KIAEQELLDASERVQLLHTQNTSLINTKKKLETD 1737
Query: 389 IAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQ 448
I+ +I+ + D I+E + +E TD + + ++L +E D + K
Sbjct: 1738 IS---QIQGEMEDIIQEARNAEEKAKKAITD---AAMMAEELKKEQDTSAHLERMK---- 1787
Query: 449 KELESTKTDLEHRKTEIEE 467
K LE T DL+HR E E+
Sbjct: 1788 KNLEQTVKDLQHRLDEAEQ 1806
>AL627308-5|CAH71336.1| 1732|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1732
Score = 49.2 bits (112), Expect = 5e-05
Identities = 63/273 (23%), Positives = 123/273 (45%), Gaps = 25/273 (9%)
Query: 407 KTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQK--ELESTKTDLEHRKTE 464
KTLQ+ +DL +L+++ R+K+ +EL K++ + K +Q+ E+ T+L +K +
Sbjct: 538 KTLQQEREDLNKELVQASERLKNQSKEL--KDAHCQRKLAMQEFMEINERLTELHTQKQK 595
Query: 465 IEEYKRLLFEKGEEIDELKSKL-STEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQ 523
+ + R +K EE+D + K+ S + ++ RE Q
Sbjct: 596 LARHVR---DKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLRE-Q 651
Query: 524 MKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKL-FELTKRQEEYDEKLQTKE 582
+ Y ++L N + Q ++ + + + Q+ KL +L K+ Y+E+L +E
Sbjct: 652 SEHYSKQLENELEGLKQ-KQISYSPGVCSIEH--QQEITKLKTDLEKKSIFYEEELSKRE 708
Query: 583 ----NEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKL--ELRNEADID 636
NEIK L + + + E KEI +L +K E+ + E + + + +
Sbjct: 709 GIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYERE 768
Query: 637 VIITLAKYKK------SLTLVLEKMSISNRVLK 663
++ + KK LT + E +SI N+ L+
Sbjct: 769 KVLLTEENKKLTSELDKLTTLYENLSIHNQQLE 801
Score = 32.7 bits (71), Expect = 4.6
Identities = 25/115 (21%), Positives = 57/115 (49%), Gaps = 6/115 (5%)
Query: 381 MKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESI 440
M+ L+++ +E++ + I K+ +QE ++ ++ + +E ++KD E E +
Sbjct: 868 MRRFAKLDMSARLELQSALDAEIRAKQAIQEELNKVKASNIITECKLKD--SEKKNLELL 925
Query: 441 LETKQCVQ--KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIK 493
E +Q ++ +EL S K +EH+ ++ + L + +D+ + S A K
Sbjct: 926 SEIEQLIKDTEELRSEK-GIEHQDSQ-HSFLAFLNTPTDALDQFERSPSCTPASK 978
>AL627308-3|CAH71337.1| 1719|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1719
Score = 49.2 bits (112), Expect = 5e-05
Identities = 63/273 (23%), Positives = 123/273 (45%), Gaps = 25/273 (9%)
Query: 407 KTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQK--ELESTKTDLEHRKTE 464
KTLQ+ +DL +L+++ R+K+ +EL K++ + K +Q+ E+ T+L +K +
Sbjct: 538 KTLQQEREDLNKELVQASERLKNQSKEL--KDAHCQRKLAMQEFMEINERLTELHTQKQK 595
Query: 465 IEEYKRLLFEKGEEIDELKSKL-STEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQ 523
+ + R +K EE+D + K+ S + ++ RE Q
Sbjct: 596 LARHVR---DKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLRE-Q 651
Query: 524 MKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKL-FELTKRQEEYDEKLQTKE 582
+ Y ++L N + Q ++ + + + Q+ KL +L K+ Y+E+L +E
Sbjct: 652 SEHYSKQLENELEGLKQ-KQISYSPGVCSIEH--QQEITKLKTDLEKKSIFYEEELSKRE 708
Query: 583 ----NEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKL--ELRNEADID 636
NEIK L + + + E KEI +L +K E+ + E + + + +
Sbjct: 709 GIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYERE 768
Query: 637 VIITLAKYKK------SLTLVLEKMSISNRVLK 663
++ + KK LT + E +SI N+ L+
Sbjct: 769 KVLLTEENKKLTSELDKLTTLYENLSIHNQQLE 801
Score = 33.1 bits (72), Expect = 3.5
Identities = 24/114 (21%), Positives = 59/114 (51%), Gaps = 6/114 (5%)
Query: 381 MKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESI 440
M+ L+++ +E++ + I K+ +QE ++ ++ + +E ++KD E E +
Sbjct: 868 MRRFAKLDMSARLELQSALDAEIRAKQAIQEELNKVKASNIITECKLKD--SEKKNLELL 925
Query: 441 LETKQCVQ--KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAI 492
E +Q ++ +EL S K +EH+ ++ + L + +D+ ++ ST ++
Sbjct: 926 SEIEQLIKDTEELRSEK-GIEHQDSQ-HSFLAFLNTPTDALDQFETVDSTPLSV 977
>AL451047-3|CAH71185.1| 1732|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1732
Score = 49.2 bits (112), Expect = 5e-05
Identities = 63/273 (23%), Positives = 123/273 (45%), Gaps = 25/273 (9%)
Query: 407 KTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQK--ELESTKTDLEHRKTE 464
KTLQ+ +DL +L+++ R+K+ +EL K++ + K +Q+ E+ T+L +K +
Sbjct: 538 KTLQQEREDLNKELVQASERLKNQSKEL--KDAHCQRKLAMQEFMEINERLTELHTQKQK 595
Query: 465 IEEYKRLLFEKGEEIDELKSKL-STEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQ 523
+ + R +K EE+D + K+ S + ++ RE Q
Sbjct: 596 LARHVR---DKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLRE-Q 651
Query: 524 MKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKL-FELTKRQEEYDEKLQTKE 582
+ Y ++L N + Q ++ + + + Q+ KL +L K+ Y+E+L +E
Sbjct: 652 SEHYSKQLENELEGLKQ-KQISYSPGVCSIEH--QQEITKLKTDLEKKSIFYEEELSKRE 708
Query: 583 ----NEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKL--ELRNEADID 636
NEIK L + + + E KEI +L +K E+ + E + + + +
Sbjct: 709 GIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYERE 768
Query: 637 VIITLAKYKK------SLTLVLEKMSISNRVLK 663
++ + KK LT + E +SI N+ L+
Sbjct: 769 KVLLTEENKKLTSELDKLTTLYENLSIHNQQLE 801
Score = 32.7 bits (71), Expect = 4.6
Identities = 25/115 (21%), Positives = 57/115 (49%), Gaps = 6/115 (5%)
Query: 381 MKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESI 440
M+ L+++ +E++ + I K+ +QE ++ ++ + +E ++KD E E +
Sbjct: 868 MRRFAKLDMSARLELQSALDAEIRAKQAIQEELNKVKASNIITECKLKD--SEKKNLELL 925
Query: 441 LETKQCVQ--KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIK 493
E +Q ++ +EL S K +EH+ ++ + L + +D+ + S A K
Sbjct: 926 SEIEQLIKDTEELRSEK-GIEHQDSQ-HSFLAFLNTPTDALDQFERSPSCTPASK 978
>AL451047-1|CAH71183.1| 1719|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1719
Score = 49.2 bits (112), Expect = 5e-05
Identities = 63/273 (23%), Positives = 123/273 (45%), Gaps = 25/273 (9%)
Query: 407 KTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQK--ELESTKTDLEHRKTE 464
KTLQ+ +DL +L+++ R+K+ +EL K++ + K +Q+ E+ T+L +K +
Sbjct: 538 KTLQQEREDLNKELVQASERLKNQSKEL--KDAHCQRKLAMQEFMEINERLTELHTQKQK 595
Query: 465 IEEYKRLLFEKGEEIDELKSKL-STEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQ 523
+ + R +K EE+D + K+ S + ++ RE Q
Sbjct: 596 LARHVR---DKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLRE-Q 651
Query: 524 MKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKL-FELTKRQEEYDEKLQTKE 582
+ Y ++L N + Q ++ + + + Q+ KL +L K+ Y+E+L +E
Sbjct: 652 SEHYSKQLENELEGLKQ-KQISYSPGVCSIEH--QQEITKLKTDLEKKSIFYEEELSKRE 708
Query: 583 ----NEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKL--ELRNEADID 636
NEIK L + + + E KEI +L +K E+ + E + + + +
Sbjct: 709 GIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYERE 768
Query: 637 VIITLAKYKK------SLTLVLEKMSISNRVLK 663
++ + KK LT + E +SI N+ L+
Sbjct: 769 KVLLTEENKKLTSELDKLTTLYENLSIHNQQLE 801
Score = 33.1 bits (72), Expect = 3.5
Identities = 24/114 (21%), Positives = 59/114 (51%), Gaps = 6/114 (5%)
Query: 381 MKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESI 440
M+ L+++ +E++ + I K+ +QE ++ ++ + +E ++KD E E +
Sbjct: 868 MRRFAKLDMSARLELQSALDAEIRAKQAIQEELNKVKASNIITECKLKD--SEKKNLELL 925
Query: 441 LETKQCVQ--KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAI 492
E +Q ++ +EL S K +EH+ ++ + L + +D+ ++ ST ++
Sbjct: 926 SEIEQLIKDTEELRSEK-GIEHQDSQ-HSFLAFLNTPTDALDQFETVDSTPLSV 977
>AL353689-9|CAI19109.1| 1732|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1732
Score = 49.2 bits (112), Expect = 5e-05
Identities = 63/273 (23%), Positives = 123/273 (45%), Gaps = 25/273 (9%)
Query: 407 KTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQK--ELESTKTDLEHRKTE 464
KTLQ+ +DL +L+++ R+K+ +EL K++ + K +Q+ E+ T+L +K +
Sbjct: 538 KTLQQEREDLNKELVQASERLKNQSKEL--KDAHCQRKLAMQEFMEINERLTELHTQKQK 595
Query: 465 IEEYKRLLFEKGEEIDELKSKL-STEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQ 523
+ + R +K EE+D + K+ S + ++ RE Q
Sbjct: 596 LARHVR---DKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLRE-Q 651
Query: 524 MKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKL-FELTKRQEEYDEKLQTKE 582
+ Y ++L N + Q ++ + + + Q+ KL +L K+ Y+E+L +E
Sbjct: 652 SEHYSKQLENELEGLKQ-KQISYSPGVCSIEH--QQEITKLKTDLEKKSIFYEEELSKRE 708
Query: 583 ----NEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKL--ELRNEADID 636
NEIK L + + + E KEI +L +K E+ + E + + + +
Sbjct: 709 GIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYERE 768
Query: 637 VIITLAKYKK------SLTLVLEKMSISNRVLK 663
++ + KK LT + E +SI N+ L+
Sbjct: 769 KVLLTEENKKLTSELDKLTTLYENLSIHNQQLE 801
Score = 32.7 bits (71), Expect = 4.6
Identities = 25/115 (21%), Positives = 57/115 (49%), Gaps = 6/115 (5%)
Query: 381 MKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESI 440
M+ L+++ +E++ + I K+ +QE ++ ++ + +E ++KD E E +
Sbjct: 868 MRRFAKLDMSARLELQSALDAEIRAKQAIQEELNKVKASNIITECKLKD--SEKKNLELL 925
Query: 441 LETKQCVQ--KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIK 493
E +Q ++ +EL S K +EH+ ++ + L + +D+ + S A K
Sbjct: 926 SEIEQLIKDTEELRSEK-GIEHQDSQ-HSFLAFLNTPTDALDQFERSPSCTPASK 978
>AL353689-7|CAI19108.1| 1719|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1719
Score = 49.2 bits (112), Expect = 5e-05
Identities = 63/273 (23%), Positives = 123/273 (45%), Gaps = 25/273 (9%)
Query: 407 KTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQK--ELESTKTDLEHRKTE 464
KTLQ+ +DL +L+++ R+K+ +EL K++ + K +Q+ E+ T+L +K +
Sbjct: 538 KTLQQEREDLNKELVQASERLKNQSKEL--KDAHCQRKLAMQEFMEINERLTELHTQKQK 595
Query: 465 IEEYKRLLFEKGEEIDELKSKL-STEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQ 523
+ + R +K EE+D + K+ S + ++ RE Q
Sbjct: 596 LARHVR---DKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLRE-Q 651
Query: 524 MKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKL-FELTKRQEEYDEKLQTKE 582
+ Y ++L N + Q ++ + + + Q+ KL +L K+ Y+E+L +E
Sbjct: 652 SEHYSKQLENELEGLKQ-KQISYSPGVCSIEH--QQEITKLKTDLEKKSIFYEEELSKRE 708
Query: 583 ----NEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKL--ELRNEADID 636
NEIK L + + + E KEI +L +K E+ + E + + + +
Sbjct: 709 GIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYERE 768
Query: 637 VIITLAKYKK------SLTLVLEKMSISNRVLK 663
++ + KK LT + E +SI N+ L+
Sbjct: 769 KVLLTEENKKLTSELDKLTTLYENLSIHNQQLE 801
Score = 33.1 bits (72), Expect = 3.5
Identities = 24/114 (21%), Positives = 59/114 (51%), Gaps = 6/114 (5%)
Query: 381 MKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESI 440
M+ L+++ +E++ + I K+ +QE ++ ++ + +E ++KD E E +
Sbjct: 868 MRRFAKLDMSARLELQSALDAEIRAKQAIQEELNKVKASNIITECKLKD--SEKKNLELL 925
Query: 441 LETKQCVQ--KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAI 492
E +Q ++ +EL S K +EH+ ++ + L + +D+ ++ ST ++
Sbjct: 926 SEIEQLIKDTEELRSEK-GIEHQDSQ-HSFLAFLNTPTDALDQFETVDSTPLSV 977
>AK097517-1|BAC05084.1| 621|Homo sapiens protein ( Homo sapiens
cDNA FLJ40198 fis, clone TESTI2019975, weakly similar to
TRICHOHYALIN. ).
Length = 621
Score = 49.2 bits (112), Expect = 5e-05
Identities = 47/245 (19%), Positives = 106/245 (43%), Gaps = 13/245 (5%)
Query: 394 EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELES 453
++ + +DS + L++ + + T +++ +++L +E D L +EL+
Sbjct: 156 DLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKE 215
Query: 454 TKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXX 513
L+ + +E K E + ELK KL K +
Sbjct: 216 KNAKLQEKLQLVESEKS---EIQLNVKELKRKLERAKLLLP----QQQLQAEADHLGKEL 268
Query: 514 XXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEE 573
++Q++ EL N NQ + + + + + + I +Q +K+ E ++ E
Sbjct: 269 QSVSAKLQAQVEE--NELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIRE 326
Query: 574 YDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK----MLNEKEEEHMNIINLLHNKLEL 629
+EK++ +E + E M QE ++ +KE++++ M+ EKEE+ + +H + ++
Sbjct: 327 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKI 386
Query: 630 RNEAD 634
R + +
Sbjct: 387 REQEE 391
Score = 48.8 bits (111), Expect = 7e-05
Identities = 51/254 (20%), Positives = 118/254 (46%), Gaps = 19/254 (7%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDL---VR 432
+ I++++ +M+ K+ E E+K + EEK QE + + E ++++ +R
Sbjct: 371 EKIRELEEKMHEQ-EKIREQEEKRQE--EEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 427
Query: 433 ELDEK-----ESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS 487
E ++K E I E ++ ++E + ++ ++ +I E + + +K + ++ K
Sbjct: 428 EQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIWKQ 487
Query: 488 TEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMK--SYYEELMNLKNQITQLRE-- 543
EK + RE + K E++ K +I + E
Sbjct: 488 EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQKEKIREQEEKI 547
Query: 544 FGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKE 603
+ + + + M+ +Q +K++E ++ E +EK+Q +E +++R E M EQE L ++E
Sbjct: 548 WEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 607
Query: 604 KEIKMLNEKEEEHM 617
+++ ++ +EH+
Sbjct: 608 EKM----QEHQEHL 617
Score = 46.8 bits (106), Expect = 3e-04
Identities = 64/313 (20%), Positives = 128/313 (40%), Gaps = 11/313 (3%)
Query: 329 DQELNKLTQSIKDNTTHLE--DIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMN 386
+ E +++ ++K+ LE + L +++LQ+ SA +++ +
Sbjct: 228 ESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR 287
Query: 387 LNIA---KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILET 443
LN K+ E+K + E+ + +E I + + E E +++ + EKE +
Sbjct: 288 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 347
Query: 444 KQCVQKELESTKTDLEHRKTEIEEYKRLLFEK---GEEIDELKSKLSTEKAIKDIXXXXX 500
++ + E E LE E EE R L EK E+I E + K E+ I++
Sbjct: 348 QEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 407
Query: 501 XXXXXXXXXXXXXXXXXXXRESQMKSY-YEELMNLKNQITQLREFGAFDNLNDVGNMINQ 559
RE + K + EE ++ + +I + + + + I +
Sbjct: 408 QEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIRE 467
Query: 560 QRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNI 619
Q + + K E+ EK+ +E ++ R E M +QE + ++E+++ EK E
Sbjct: 468 QEEIWRQKEKMHEQ--EKIWKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEK 525
Query: 620 INLLHNKLELRNE 632
I K+ + E
Sbjct: 526 IREQEEKIREQKE 538
Score = 44.0 bits (99), Expect = 0.002
Identities = 50/257 (19%), Positives = 110/257 (42%), Gaps = 18/257 (7%)
Query: 394 EIEKKYNDSIEEKKTLQENIDDL--RTDLLESELRVKDLV-RELDEKESILETK-QCVQK 449
E+E+ + +KK I++L D L EL + EL EK + L+ K Q V+
Sbjct: 170 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 229
Query: 450 ELESTKTDLEHRKTEIEEYKRLLFEK---------GEEIDELKSKLSTEKAIKDIXXXXX 500
E + +++ K ++E K LL ++ G+E+ + +KL + ++
Sbjct: 230 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 289
Query: 501 XXXXXXXXXXXXXXXXXXXR-ESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQ 559
+ + Q + E+ ++ Q ++R + + + + +
Sbjct: 290 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRR--QEEMMWEKEEKMRR 347
Query: 560 QRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEK--EIKMLNEKEEEHM 617
Q + ++E ++ +E + KE +I+ L E M EQE + ++EK E + + E+E+
Sbjct: 348 QEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 407
Query: 618 NIINLLHNKLELRNEAD 634
+ + ++R + +
Sbjct: 408 QEAKMWRQEEKIREQEE 424
>AJ518975-1|CAD57745.1| 1719|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1719
Score = 49.2 bits (112), Expect = 5e-05
Identities = 63/273 (23%), Positives = 123/273 (45%), Gaps = 25/273 (9%)
Query: 407 KTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQK--ELESTKTDLEHRKTE 464
KTLQ+ +DL +L+++ R+K+ +EL K++ + K +Q+ E+ T+L +K +
Sbjct: 538 KTLQQEREDLNKELVQASERLKNQSKEL--KDAHCQRKLAMQEFMEINERLTELHTQKQK 595
Query: 465 IEEYKRLLFEKGEEIDELKSKL-STEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQ 523
+ + R +K EE+D + K+ S + ++ RE Q
Sbjct: 596 LARHVR---DKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLRE-Q 651
Query: 524 MKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKL-FELTKRQEEYDEKLQTKE 582
+ Y ++L N + Q ++ + + + Q+ KL +L K+ Y+E+L +E
Sbjct: 652 SEHYSKQLENELEGLKQ-KQISYSPGVCSIEH--QQEITKLKTDLEKKSIFYEEELSKRE 708
Query: 583 ----NEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKL--ELRNEADID 636
NEIK L + + + E KEI +L +K E+ + E + + + +
Sbjct: 709 GIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYERE 768
Query: 637 VIITLAKYKK------SLTLVLEKMSISNRVLK 663
++ + KK LT + E +SI N+ L+
Sbjct: 769 KVLLTEENKKLTSELDKLTTLYENLSIHNQQLE 801
Score = 33.1 bits (72), Expect = 3.5
Identities = 24/114 (21%), Positives = 59/114 (51%), Gaps = 6/114 (5%)
Query: 381 MKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESI 440
M+ L+++ +E++ + I K+ +QE ++ ++ + +E ++KD E E +
Sbjct: 868 MRRFAKLDMSARLELQSALDAEIRAKQAIQEELNKVKASNIITECKLKD--SEKKNLELL 925
Query: 441 LETKQCVQ--KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAI 492
E +Q ++ +EL S K +EH+ ++ + L + +D+ ++ ST ++
Sbjct: 926 SEIEQLIKDTEELRSEK-GIEHQDSQ-HSFLAFLNTPTDALDQFETVDSTPLSV 977
>AF111785-1|AAD29951.1| 1939|Homo sapiens myosin heavy chain IIx/d
protein.
Length = 1939
Score = 49.2 bits (112), Expect = 5e-05
Identities = 75/477 (15%), Positives = 186/477 (38%), Gaps = 26/477 (5%)
Query: 148 FKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDC 207
FK K ++ +S ++++ + K K KE A+ + + L++ ++E ND+
Sbjct: 838 FKIKPLL---KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQ 894
Query: 208 LRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPY--ANRNXXXXXXXXX 265
++ A+ + R +L L + E+ ++ + A +
Sbjct: 895 VQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSEL 954
Query: 266 XXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXX 325
+ ++ + +H + V+ + + A L++ ++ ++ +
Sbjct: 955 KKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDL 1014
Query: 326 EDFDQELNKLTQS---IKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMK 382
+ + ++N LT++ ++ LE +K++ +S D++
Sbjct: 1015 QAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESAMDIE 1074
Query: 383 HEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILE 442
++ ++++K E LQ I+D + ++ + ++K+L ++E E +E
Sbjct: 1075 NDKQ-------QLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIE 1127
Query: 443 TKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEID---ELKSKLSTE--KAIKDIXX 497
++ + + E ++DL E+EE L E G E+ K E K +D+
Sbjct: 1128 AERASRAKAEKQRSDLSR---ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEE 1184
Query: 498 XXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMI 557
Q+ + L+ + ++++ D+L +
Sbjct: 1185 ATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKM--EIDDLASNMETV 1242
Query: 558 NQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEI-KMLNEKE 613
++ + L ++ + E+ +++TKE E +RL+ +T Q L + E + L+EK+
Sbjct: 1243 SKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKD 1299
Score = 46.8 bits (106), Expect = 3e-04
Identities = 73/381 (19%), Positives = 163/381 (42%), Gaps = 26/381 (6%)
Query: 277 DRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLT 336
D+L + + QL+ ++ V + E+ +E + +R + +D + L K+
Sbjct: 910 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 969
Query: 337 QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHE---MNLNIAKLI 393
+ ++++ L ++ +++ D++ E +N I
Sbjct: 970 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKI 1029
Query: 394 EIEKKYND---SIEEKKTLQENID----DLRTDLL---ESELRVKDLVRELDEKESILET 443
++E++ +D S+E++K ++ +++ L DL ES + +++ ++LDEK E
Sbjct: 1030 KLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESAMDIENDKQQLDEKLKKKEF 1089
Query: 444 KQC-VQKELESTKTDLEHRKTEIEEYKRLLFEKGEEID-ELKSKLSTEKAIKDIXXXXXX 501
+ +Q ++E + + +I+E + + E EEI+ E S+ EK D+
Sbjct: 1090 EMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEE 1149
Query: 502 XXXXXXXXXXXXXXXXXX---RESQMKSYYEEL--MNLKNQITQ--LREFGAFDNLNDVG 554
RE++ + +L L+++ T LR+ A D++ ++G
Sbjct: 1150 ISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHA-DSVAELG 1208
Query: 555 NMI-NQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKE 613
I N QR K +L K + E ++ + ++ + ++ E + E ++ + KE
Sbjct: 1209 EQIDNLQRVKQ-KLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKE 1267
Query: 614 EEHMNIIN-LLHNKLELRNEA 633
EE +IN L + L+ E+
Sbjct: 1268 EEQQRLINDLTAQRARLQTES 1288
Score = 44.0 bits (99), Expect = 0.002
Identities = 103/590 (17%), Positives = 217/590 (36%), Gaps = 40/590 (6%)
Query: 42 QEKMVTFEKSKKELEDRQNQVMELYASLRNTHR-KMKLLGQKV-NLPSAEELHIMNVAKL 99
+++ F+K +++LE+ Q A+LR H + LG+++ NL ++ + K
Sbjct: 1169 KKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQ----KLEKE 1224
Query: 100 SPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFES 159
E +++ + A T+ +K ++ K+ +L D+ E K +E
Sbjct: 1225 KSEMKMEI----DDLASNMETV-SKAKGNLEKMCR---ALEDQLSEIKTKEEEQQRLIND 1276
Query: 160 LMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKN--ANETMA 217
L +Q + T++ ++ + E D L S L + + F ++I ++ L + A +A
Sbjct: 1277 LTAQRARLQTESGEYS-RQLD-EKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALA 1334
Query: 218 LQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKD 277
L++ C L +R+Q + R +
Sbjct: 1335 HALQSSRHDCDL---------LREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQ 1385
Query: 278 RLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQ 337
R E K +R+ E +E ++ SLE+T D ++ N
Sbjct: 1386 RTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERT-NAACA 1444
Query: 338 SIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEK 397
++ + + I ++ S S + + +K+ ++ +L +++
Sbjct: 1445 ALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKR 1504
Query: 398 KYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTD 457
E K LQ+ I DL + E R+ +L + K+ + + K +Q LE +
Sbjct: 1505 -------ENKNLQQEISDLTEQIAEGGKRIHELEKI---KKQVEQEKSELQAALEEAEAS 1554
Query: 458 LEHRKTEIEEYKRLLFEKGEEID-ELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXX 516
LEH + +I + L + E+D ++ K +K
Sbjct: 1555 LEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRND 1614
Query: 517 XXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDE 576
+ +M+ E+ N ++ A N + ++ + L + + QE+ E
Sbjct: 1615 AIRLKKKMEGDLNEMEIQLNHANRMAA-EALRNYRNTQAILKDTQLHLDDALRSQEDLKE 1673
Query: 577 KLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNK 626
+L E L + E L + E+ K+ ++ + + LLH +
Sbjct: 1674 QLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQ 1723
Score = 34.3 bits (75), Expect = 1.5
Identities = 87/472 (18%), Positives = 175/472 (37%), Gaps = 27/472 (5%)
Query: 37 LKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKV--NLPSAEE-LHI 93
L V +EK T E K L + + E A L + ++ Q+ +L + E+ ++
Sbjct: 965 LAKVEKEKHAT-ENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNT 1023
Query: 94 MNVAKLSPEQLLQLCAGG---EPKA---LEHST--LDNKVTFDVNKLLNIPNSLVDKCEE 145
+ AK+ EQ + G E K LE + L+ + ++I N + +E
Sbjct: 1024 LTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESAMDIENDK-QQLDE 1082
Query: 146 TLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDII 205
L K++ ++ +S + E+ + + L KIKE A + L+ ++ R K
Sbjct: 1083 KLKKKEFEMSGLQSKIEDEQALGMQ-LQKKIKELQARIEELEEEIEAERASRAKAEKQRS 1141
Query: 206 DCLRKNANETMALQLRTKELSCALSDLNTQNAE---MRKQIHSG--DHHRPYAN-RNXXX 259
D R+ + L+ S + + AE MR+ + H A R
Sbjct: 1142 DLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHA 1201
Query: 260 XXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXX 319
+K +L + + ++K ++ + + +A+ + R +
Sbjct: 1202 DSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLS 1261
Query: 320 XXXXXXEDFDQELNKLT-QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSI 378
E+ + +N LT Q + T E EK ++ + I
Sbjct: 1262 EIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEK-----DTLVSQLSRGKQAFTQQI 1316
Query: 379 KDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKE 438
+++K ++ I + S + L+E ++ + E + + E+ +
Sbjct: 1317 EELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWR 1376
Query: 439 SILETKQCVQ-KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
+ ET + +ELE K L R + EE+ + K +++ K +L E
Sbjct: 1377 TKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNE 1428
Score = 33.1 bits (72), Expect = 3.5
Identities = 32/139 (23%), Positives = 59/139 (42%), Gaps = 11/139 (7%)
Query: 329 DQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLN 388
++ N L I++ LE +R K+ + N S+ + K ++ +
Sbjct: 1679 ERRANLLQAEIEELRATLEQTERSR-KIAEQELLDASERVQLLHTQNTSLINTKKKLETD 1737
Query: 389 IAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQ 448
I+ +I+ + D I+E + +E TD + + ++L +E D + K
Sbjct: 1738 IS---QIQGEMEDIIQEARNAEEKAKKAITD---AAMMAEELKKEQDTSAHLERMK---- 1787
Query: 449 KELESTKTDLEHRKTEIEE 467
K LE T DL+HR E E+
Sbjct: 1788 KNLEQTVKDLQHRLDEAEQ 1806
>AB208968-1|BAD92205.1| 1702|Homo sapiens CDC42 binding protein
kinase alpha variant protein.
Length = 1702
Score = 49.2 bits (112), Expect = 5e-05
Identities = 63/273 (23%), Positives = 123/273 (45%), Gaps = 25/273 (9%)
Query: 407 KTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQK--ELESTKTDLEHRKTE 464
KTLQ+ +DL +L+++ R+K+ +EL K++ + K +Q+ E+ T+L +K +
Sbjct: 549 KTLQQEREDLNKELVQASERLKNQSKEL--KDAHCQRKLAMQEFMEINERLTELHTQKQK 606
Query: 465 IEEYKRLLFEKGEEIDELKSKL-STEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQ 523
+ + R +K EE+D + K+ S + ++ RE Q
Sbjct: 607 LARHVR---DKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLRE-Q 662
Query: 524 MKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKL-FELTKRQEEYDEKLQTKE 582
+ Y ++L N + Q ++ + + + Q+ KL +L K+ Y+E+L +E
Sbjct: 663 SEHYSKQLENELEGLKQ-KQISYSPGVCSIEH--QQEITKLKTDLEKKSIFYEEELSKRE 719
Query: 583 ----NEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKL--ELRNEADID 636
NEIK L + + + E KEI +L +K E+ + E + + + +
Sbjct: 720 GIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYERE 779
Query: 637 VIITLAKYKK------SLTLVLEKMSISNRVLK 663
++ + KK LT + E +SI N+ L+
Sbjct: 780 KVLLTEENKKLTSELDKLTTLYENLSIHNQQLE 812
Score = 32.7 bits (71), Expect = 4.6
Identities = 23/107 (21%), Positives = 55/107 (51%), Gaps = 6/107 (5%)
Query: 381 MKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESI 440
M+ L+++ +E++ + I K+ +QE ++ ++ + +E ++KD E E +
Sbjct: 879 MRRFAKLDMSARLELQSALDAEIRAKQAIQEELNKVKASNIITECKLKD--SEKKNLELL 936
Query: 441 LETKQCVQ--KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSK 485
E +Q ++ +EL S K +EH+ ++ + L + +D+ + K
Sbjct: 937 SEIEQLIKDTEELRSEK-GIEHQDSQ-HSFLAFLNTPTDALDQFERK 981
>X52889-1|CAA37068.1| 1934|Homo sapiens cardiac beta myosin heavy
chain protein.
Length = 1934
Score = 48.8 bits (111), Expect = 7e-05
Identities = 112/626 (17%), Positives = 233/626 (37%), Gaps = 33/626 (5%)
Query: 23 EQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQK 82
EQ+++ + +L + ++ + LED + EL A RN + L +
Sbjct: 894 EQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRNVEDECSELKRD 953
Query: 83 VN---LPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKL----LNI 135
++ L A+ + + + L + AG + + + T + K + ++ L
Sbjct: 954 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLD-EIIAKLTKEKKALQEAHQQALDDLQA 1012
Query: 136 PNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRT 195
V+ + K ++ ++ E + QEK + K ++ + L + S+ L
Sbjct: 1013 EEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAK-RKLEGDLKLTQESIMDLEN 1071
Query: 196 EFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANR 255
+ K+ D + L+K E AL R ++ S L + E++ +I + A R
Sbjct: 1072 D--KQQLD--ERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELE-AER 1126
Query: 256 NXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVX 315
+ +RL A +E + EA ++ R + LE
Sbjct: 1127 TARAKVEKLRSDLSRELEEISERLEEAGGATSCQIEMNKKREAEFQKMRRD---LEEATL 1183
Query: 316 XXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQ-----SXXXXXXXXXXXX 370
+ + +L + I DN ++ L +EK +
Sbjct: 1184 QHEATAAALRKKHADSVAELGEQI-DNLQRVKQ-KLEKEKSEFKLELDDVTSNMEQIIKA 1241
Query: 371 SASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDL 430
A+ K + ++ +MN + +K E ++ ND ++ LQ +L L E E + L
Sbjct: 1242 KANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQL 1301
Query: 431 VR-ELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS-- 487
R +L + + + K+ +++E+++ K L H LL E+ EE E K++L
Sbjct: 1302 TRGKLTYTQQLEDLKRQLEEEVKA-KNALAHALQSARHDCDLLREQYEEETEAKAELQRV 1360
Query: 488 TEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYE--ELMNLKNQITQLREFG 545
KA ++ +++ E E +N K + +
Sbjct: 1361 LSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHR 1420
Query: 546 AFDNLNDVGNMINQQRDKLFELTKRQEEYDEKL---QTKENEIKRLVESMTEQEHVLNKK 602
+ + D+ + + L K+Q +D+ L + K E + +ES ++ L+ +
Sbjct: 1421 LQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTE 1480
Query: 603 EKEIKMLNEKEEEHMNIINLLHNKLE 628
++K E+ EH+ + L+
Sbjct: 1481 LFKLKNAYEESLEHLETFKRENKNLQ 1506
Score = 47.6 bits (108), Expect = 2e-04
Identities = 49/263 (18%), Positives = 111/263 (42%), Gaps = 9/263 (3%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLV 431
AS + +K + + A+ E+E+K ++EK LQ + + +L ++E R L+
Sbjct: 850 ASMKEEFTALKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLI 909
Query: 432 RELDEKES-ILETKQCVQKELESTKTDLEHRKTEIE----EYKRLLFEKGEEIDEL-KSK 485
+ + E+ + E + ++ E E +L +K +E E KR + + + ++ K K
Sbjct: 910 KNKIQLEAKVKEMNERLEDE-EEMNAELTAKKRNVEDECSELKRDIDDLELTLAKVEKEK 968
Query: 486 LSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFG 545
+TE +K++ + + E + N +T+ +
Sbjct: 969 HATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAE-EDKVNTLTKAK-VK 1026
Query: 546 AFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKE 605
++D+ + Q++ +L + + + + L+ + I L + + L KK+ E
Sbjct: 1027 LEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFE 1086
Query: 606 IKMLNEKEEEHMNIINLLHNKLE 628
+ LN + E+ + + L KL+
Sbjct: 1087 LNALNARIEDEQALGSQLQKKLK 1109
Score = 46.0 bits (104), Expect = 5e-04
Identities = 49/269 (18%), Positives = 119/269 (44%), Gaps = 4/269 (1%)
Query: 389 IAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQ 448
+ K E EK+ EE L+E ++ E E ++ L++E ++ + ++ +Q
Sbjct: 839 LLKSAEREKEMASMKEEFTALKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL 898
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA-IKDIXXXXXXXXXXXX 507
+ E L K ++E + + E+ E+ +E+ ++L+ +K ++D
Sbjct: 899 ADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRNVEDECSELKRDIDDLE 958
Query: 508 XXXXXXXXXXXXRESQMKSYYEELMNLKNQITQL-REFGAFDNLNDVG-NMINQQRDKLF 565
E+++K+ EE+ L I +L +E A + + + + DK+
Sbjct: 959 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVN 1018
Query: 566 ELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHN 625
LTK + + ++++ E +++ + + E K E ++K+ E + N L
Sbjct: 1019 TLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDE 1078
Query: 626 KLELRNEADIDVIITLAKYKKSLTLVLEK 654
+L+ + + +++ + + +++L L+K
Sbjct: 1079 RLK-KKDFELNALNARIEDEQALGSQLQK 1106
Score = 42.3 bits (95), Expect = 0.006
Identities = 83/474 (17%), Positives = 185/474 (39%), Gaps = 32/474 (6%)
Query: 22 NEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQ 81
+ Q+ S S ++ KLK ++E + E K+E ++ Q ++ +L L ++ + + L +
Sbjct: 1469 SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEK 1528
Query: 82 KVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVD 141
AE++ + + + + L E K L N++ ++ + L + +
Sbjct: 1529 VRKQLEAEKMELQSALEEAEASL----EHEEGKILRAQLEFNQIKAEIERKLAEKD---E 1581
Query: 142 KCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIK---EFNAENDLLKSSLDQLRTEFL 198
+ E+ +++ ++ + E + L +K K + N E ++ S +++ E
Sbjct: 1582 EMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN-EMEIQLSHANRMAAEAQ 1640
Query: 199 KEINDIIDCLRK---NANETMALQLRTKELSCAL---SDLNTQNAEMRKQIHSGDHHRPY 252
K++ + L+ ++ + KE + ++L + E+R + + R
Sbjct: 1641 KQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLQAELEELRAVVEQTERSRKL 1700
Query: 253 ANRNXXXXXXXXXXXXXXXXSIM--KDRLSRAEHQLKTNVERVVQLEAALEQARSESWSL 310
A+R S++ K ++ QL+T VE VQ E+ ++ +
Sbjct: 1701 ADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITD 1760
Query: 311 ERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHL---EDIAL--AREKLQSXXXXXXX 365
+ ++ + Q+IKD L E IAL +++LQ
Sbjct: 1761 AAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRE 1820
Query: 366 XXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESEL 425
A ++ + +K M + ++ E+ + + + LQ+ +D L +L
Sbjct: 1821 LENELEAEQKRNAESVK-GMRKSERRIKELTYQTEEDRKNLLRLQDLVDKL-------QL 1872
Query: 426 RVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI 479
+VK R+ +E E T ++++ + E R E L K +I
Sbjct: 1873 KVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDI 1926
Score = 41.1 bits (92), Expect = 0.013
Identities = 105/613 (17%), Positives = 233/613 (38%), Gaps = 37/613 (6%)
Query: 14 DGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTH 73
+G L L+E+E++ S+ +T+ K + +++ E K++LE+ L +L++
Sbjct: 1284 NGELSRQLDEKEALISQ---LTRGKLTYTQQL---EDLKRQLEEEVKAKNALAHALQSAR 1337
Query: 74 RKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLL 133
LL ++ + + + V + ++ Q E A++ + + + + L
Sbjct: 1338 HDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1397
Query: 134 NIPNSLVD----KCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSS 189
V+ KC + + N E LM + + + K+ N D + +
Sbjct: 1398 QEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNF--DKILAE 1455
Query: 190 LDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHH 249
Q E E+ R + E L+ +E L +N ++++I
Sbjct: 1456 WKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQ 1515
Query: 250 RPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWS 309
+ + + + L AE L+ ++++ + Q ++E
Sbjct: 1516 LGSSGKTIHELEKVRKQLEAEKMEL-QSALEEAEASLEHEEGKILRAQLEFNQIKAE--- 1571
Query: 310 LERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQ---SXXXXXXXX 366
+ER + + + ++ L S+ T + ++K++ +
Sbjct: 1572 IERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSH 1631
Query: 367 XXXXSASYNKSIKDMKH-----EMNLNIAKLIEIEKKYNDSIEEKKT-LQENIDDLRTDL 420
+A K +K ++ ++ L+ A + K N +I E++ LQ +++LR +
Sbjct: 1632 ANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLQAELEELRAVV 1691
Query: 421 LESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIE-EYKRLLFEKGEEI 479
++E R+L ++E ++ET + VQ L S T L ++K +++ + +L E E +
Sbjct: 1692 EQTERS-----RKLADRE-LIETSERVQL-LHSQNTSLINQKKKMDADLSQLQTEVEEAV 1744
Query: 480 DELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQIT 539
E ++ + EKA K I + M+ ++L + ++
Sbjct: 1745 QECRN--AEEKAKKAI--TDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAE 1800
Query: 540 QLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVL 599
Q+ G L + + + ++L KR E + ++ E IK L E L
Sbjct: 1801 QIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNL 1860
Query: 600 NKKEKEIKMLNEK 612
+ + + L K
Sbjct: 1861 LRLQDLVDKLQLK 1873
>X51591-1|CAA35940.1| 1151|Homo sapiens beta-myosin heavy chain
(1151 AA) protein.
Length = 1151
Score = 48.8 bits (111), Expect = 7e-05
Identities = 52/265 (19%), Positives = 110/265 (41%), Gaps = 13/265 (4%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLV 431
AS + +K + + A+ E+E+K ++EK LQ + + +L ++E R L+
Sbjct: 66 ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLI 125
Query: 432 R-------ELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDEL-K 483
+ ++ E LE ++ + EL + K LE E E KR + + + ++ K
Sbjct: 126 KNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLE---DECSELKRDIDDLELTLAKVEK 182
Query: 484 SKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLRE 543
K +TE +K++ + + E + N +T+ +
Sbjct: 183 EKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAE-EDKVNTLTKAK- 240
Query: 544 FGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKE 603
++D+ + Q++ +L + + + + L+ + I L + E L KK+
Sbjct: 241 VKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLEERLKKKD 300
Query: 604 KEIKMLNEKEEEHMNIINLLHNKLE 628
E+ LN + E+ + + L KL+
Sbjct: 301 FELNALNARIEDEQALGSQLQKKLK 325
Score = 47.2 bits (107), Expect = 2e-04
Identities = 90/493 (18%), Positives = 184/493 (37%), Gaps = 25/493 (5%)
Query: 149 KRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCL 208
K ++ ++ E + QEK + K ++ + L + S+ L + K+ + + L
Sbjct: 242 KLEQQVDDLEGSLEQEKKVRMDLERAK-RKLEGDLKLTQESIMDLEND--KQ--QLEERL 296
Query: 209 RKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXX 268
+K E AL R ++ S L + E++ +I + A R
Sbjct: 297 KKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELE-AERTARAKVEKLRSDL 355
Query: 269 XXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDF 328
+ +RL A +E + EA ++ R + LE +
Sbjct: 356 SRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRD---LEEATLQHEATAAALRKKH 412
Query: 329 DQELNKLTQSIKDNTTHLEDIALAREKLQ-----SXXXXXXXXXXXXSASYNKSIKDMKH 383
+ +L + I DN ++ L +EK + A+ K + ++
Sbjct: 413 ADSVAELGEQI-DNLQRVKQ-KLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLED 470
Query: 384 EMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVR-ELDEKESILE 442
+MN + +K E ++ ND ++ LQ +L L E E + L R +L + + +
Sbjct: 471 QMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLED 530
Query: 443 TKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS--TEKAIKDIXXXXX 500
K+ +++E+++ K L H LL E+ EE E K++L KA ++
Sbjct: 531 LKRQLEEEVKA-KNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT 589
Query: 501 XXXXXXXXXXXXXXXXXXXRESQMKSYYE--ELMNLKNQITQLREFGAFDNLNDVGNMIN 558
+++ E E +N K + + + + D+ +
Sbjct: 590 KYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVE 649
Query: 559 QQRDKLFELTKRQEEYDEKL---QTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEE 615
+ L K+Q +D+ L + K E + +ES ++ L+ + ++K E+ E
Sbjct: 650 RSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLE 709
Query: 616 HMNIINLLHNKLE 628
H+ + L+
Sbjct: 710 HLETFKRENKNLQ 722
Score = 45.6 bits (103), Expect = 6e-04
Identities = 49/269 (18%), Positives = 119/269 (44%), Gaps = 4/269 (1%)
Query: 389 IAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQ 448
+ K E EK+ EE L+E ++ E E ++ L++E ++ + ++ +Q
Sbjct: 55 LLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL 114
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA-IKDIXXXXXXXXXXXX 507
+ E L K ++E + + E+ E+ +E+ ++L+ +K ++D
Sbjct: 115 ADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLE 174
Query: 508 XXXXXXXXXXXXRESQMKSYYEELMNLKNQITQL-REFGAFDNLNDVG-NMINQQRDKLF 565
E+++K+ EE+ L I +L +E A + + + + DK+
Sbjct: 175 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVN 234
Query: 566 ELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHN 625
LTK + + ++++ E +++ + + E K E ++K+ E + N L
Sbjct: 235 TLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLEE 294
Query: 626 KLELRNEADIDVIITLAKYKKSLTLVLEK 654
+L+ + + +++ + + +++L L+K
Sbjct: 295 RLK-KKDFELNALNARIEDEQALGSQLQK 322
Score = 39.9 bits (89), Expect = 0.030
Identities = 108/628 (17%), Positives = 234/628 (37%), Gaps = 42/628 (6%)
Query: 14 DGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTH 73
+G L L+E+E++ S+ +T+ K + +++ E K++LE+ L +L++
Sbjct: 500 NGELSRQLDEKEALISQ---LTRGKLTYTQQL---EDLKRQLEEEVKAKNALAHALQSAR 553
Query: 74 RKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLL 133
LL ++ + + + V + ++ Q E A++ + + + + L
Sbjct: 554 HDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 613
Query: 134 NIPNSLVD----KCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSS 189
V+ KC + + N E LM + + + K+ N D + +
Sbjct: 614 QEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNF--DKILAE 671
Query: 190 LDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHH 249
Q E E+ R + E L+ +E L +N ++++I
Sbjct: 672 WKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQ 731
Query: 250 RPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWS 309
+ + + + L AE L+ ++++ + Q ++E
Sbjct: 732 LGSSGKTIHELEKVRKQLEAEKMEL-QSALEEAEASLEHEEGKILRAQLEFNQIKAE--- 787
Query: 310 LERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXX 369
+ER + + + ++ L S+ T + ++K++
Sbjct: 788 IERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSH 847
Query: 370 XSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKD 429
+ ++ K +K +L L + + + +D++ L+ENI + E R
Sbjct: 848 ANRMAAEAQKQVKSLQSL----LKDTQIQLDDAVRANDDLKENIAIV-------ERRNNL 896
Query: 430 LVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
L EL+E +++E + +K + + R + L + +++D S+L TE
Sbjct: 897 LQAELEELRAVVEQTERSRKLADEELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTE 956
Query: 490 KAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEEL-MNLKNQITQLREFGAFD 548
+E ++ E + N++ I L+ D
Sbjct: 957 VEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQH--RLD 1014
Query: 549 NLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM 608
+ + + +L +L R E + +L E E KR ES+ + K E+ IK
Sbjct: 1015 EAEQIA--LKGGKKQLQKLEARVRELENEL---EAEQKRNAESVKG----MRKSERRIKE 1065
Query: 609 LN-EKEEEHMNIINL--LHNKLELRNEA 633
L + EE+ N++ L L +KL+L+ +A
Sbjct: 1066 LTYQTEEDRKNLLRLQDLVDKLQLKVKA 1093
Score = 39.1 bits (87), Expect = 0.053
Identities = 84/477 (17%), Positives = 183/477 (38%), Gaps = 37/477 (7%)
Query: 22 NEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQ 81
+ Q+ S S ++ KLK ++E + E K+E ++ Q ++ +L L ++ + + L +
Sbjct: 685 SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEK 744
Query: 82 KVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVD 141
AE++ + + + + L E K L N++ ++ + L + +
Sbjct: 745 VRKQLEAEKMELQSALEEAEASL----EHEEGKILRAQLEFNQIKAEIERKLAEKD---E 797
Query: 142 KCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIK---EFNAENDLLKSSLDQLRTEFL 198
+ E+ +++ ++ + E + L +K K + N E ++ S +++ E
Sbjct: 798 EMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN-EMEIQLSHANRMAAEAQ 856
Query: 199 KEINDIIDCLRK---------NANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHH 249
K++ + L+ AN+ + + E L L + E+R + +
Sbjct: 857 KQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNL--LQAELEELRAVVEQTERS 914
Query: 250 RPYANRNXXXXXXXXXXXXXXXXSIM--KDRLSRAEHQLKTNVERVVQLEAALEQARSES 307
R A+ S++ K ++ QL+T VE VQ E+ ++
Sbjct: 915 RKLADEELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKA 974
Query: 308 WSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHL---EDIAL--AREKLQSXXXX 362
+ + ++ + Q+IKD L E IAL +++LQ
Sbjct: 975 ITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEAR 1034
Query: 363 XXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLE 422
A ++ + +K M + ++ E+ + + + LQ+ +D L
Sbjct: 1035 VRELENELEAEQKRNAESVK-GMRKSERRIKELTYQTEEDRKNLLRLQDLVDKL------ 1087
Query: 423 SELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI 479
+L+VK R+ +E E T ++++ + E R E L K +I
Sbjct: 1088 -QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDI 1143
>AB059622-1|BAB69690.1| 1594|Homo sapiens Rb1-inducible coiled coil
protein protein.
Length = 1594
Score = 48.8 bits (111), Expect = 7e-05
Identities = 90/455 (19%), Positives = 179/455 (39%), Gaps = 54/455 (11%)
Query: 176 IKEFNAEND----LLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSD 231
+K+ + END LL++ L L LKE+ D + E + R +L +
Sbjct: 962 LKKLHVENDEKLQLLRAELQSLEQSHLKELEDTLQVRHIQEFEKVMTDHRV-----SLEE 1016
Query: 232 LNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVE 291
L +N ++ QI ++ S + D + E +L
Sbjct: 1017 LKKENQQIINQIQE-------SHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEA 1069
Query: 292 RVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIAL 351
+++ LE++R++ +++ E+ E++KL Q I+DN + + + L
Sbjct: 1070 ETDEIKILLEESRAQQKETLKSLLEQET------ENLRTEISKLNQKIQDNNENYQ-VGL 1122
Query: 352 AR----------EKLQSXXXXXXXXXXXXSASYNK--SIKDMKHEMNLNIAK-LIEIEKK 398
A +++ A NK S+ + E+ N+ + +IE++ K
Sbjct: 1123 AELRTLMTIEKDQRISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSK 1182
Query: 399 YNDSI-------EEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKEL 451
+ + +EK T QE + LE + R K + + ++E +++ C +K+
Sbjct: 1183 LDSELSALERQKDEKITQQEEKYEAIIQNLEKD-RQKLVSSQEQDREQLIQKLNC-EKD- 1239
Query: 452 ESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXX 511
E+ +T L+ K E E ++ L EK + L+++++ AI
Sbjct: 1240 EAIQTALKEFKLEREVVEKELLEK---VKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQ 1296
Query: 512 XXXXXXXXR-ESQMKSYYEELMNLKNQIT--QLREFGAFDNLNDVG--NMINQQRDKLFE 566
+ E Q K EE+ N++ + Q F + N+IN DKL
Sbjct: 1297 EEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKS 1356
Query: 567 LTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNK 601
++QE + +++ + RL+E + E ++K
Sbjct: 1357 TMQQQERDKDLIESLSEDRARLLEEKKKLEEEVSK 1391
Score = 36.7 bits (81), Expect = 0.28
Identities = 91/461 (19%), Positives = 188/461 (40%), Gaps = 45/461 (9%)
Query: 4 EELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVM 63
E+L++ + + L E E H I + + V + V+ E+ KKE + NQ+
Sbjct: 971 EKLQLLRAELQSLEQSHLKELEDTLQVRH-IQEFEKVMTDHRVSLEELKKENQQIINQIQ 1029
Query: 64 ELYAS-LRNTHRKMKLLGQKVNLPSAE--ELHIMNVAKLSPEQLLQLCAGGEPKALEHST 120
E +A ++ ++++ L KV+ S +L + K + +++ E +A + T
Sbjct: 1030 ESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAETDEIKILL-EESRAQQKET 1088
Query: 121 LDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFN 180
L + + + L + L K ++ + + +LM+ EK + ++ I
Sbjct: 1089 LKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEK---DQRISELISRHE 1145
Query: 181 AENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMR 240
E+++LK+ L+++ T + +I KN E + ++L++K L LS L Q E
Sbjct: 1146 EESNILKAELNKV-TSLHNQAFEI----EKNLKEQI-IELQSK-LDSELSALERQKDEKI 1198
Query: 241 KQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAAL 300
Q + + R + K N E+ ++ AL
Sbjct: 1199 TQ------------QEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTAL 1246
Query: 301 EQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXX 360
++ + LER V + + S + +++ L +A +EKLQ
Sbjct: 1247 KE-----FKLEREVVEKELLEKVKHLENQIAKSPAIDSTRGDSSSL--VAELQEKLQEEK 1299
Query: 361 XXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDL 420
N+ ++ N+ + + E + +N + +K +ENI + +D
Sbjct: 1300 AKFLEQLEEQEKRKNEEMQ------NVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDK 1353
Query: 421 LESEL----RVKDLVRELDE-KESILETKQCVQKELESTKT 456
L+S + R KDL+ L E + +LE K+ +++E+ ++
Sbjct: 1354 LKSTMQQQERDKDLIESLSEDRARLLEEKKKLEEEVSKLRS 1394
Score = 36.3 bits (80), Expect = 0.37
Identities = 23/73 (31%), Positives = 41/73 (56%), Gaps = 4/73 (5%)
Query: 558 NQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMT--EQEHVLNKKEKE--IKMLNEKE 613
N+ KL L K EE + K++ + E+ L E + + E L K EKE I + NEK+
Sbjct: 872 NEYEGKLDGLIKETEENENKIKKLKGELVCLEEVLQNKDNEFALVKHEKEAVICLQNEKD 931
Query: 614 EEHMNIINLLHNK 626
++ + + N++H++
Sbjct: 932 QKLLEMENIMHSQ 944
>BC101026-1|AAI01027.1| 490|Homo sapiens SASS6 protein protein.
Length = 490
Score = 48.4 bits (110), Expect = 9e-05
Identities = 58/296 (19%), Positives = 126/296 (42%), Gaps = 12/296 (4%)
Query: 337 QSIKDNTTHLEDIALA-REKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEI 395
QS+ D T L+ EK Q +A NK +++ +E + ++
Sbjct: 2 QSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQY 61
Query: 396 EKKYNDSIEEKKTL-QENIDDLRTDLLESELRVKDLV-RELDEKESILETK---QCVQKE 450
++++ ++ + L Q+NI L+ L E E+ KDL R+ +I E K V++E
Sbjct: 62 QQQHEQQKKDLEILHQQNIHQLQNRLSELEVANKDLTERKYKGDSTIRELKAKLSGVEEE 121
Query: 451 LESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLST-EKAIKD---IXXXXXXXXXXX 506
L+ TK ++ + E EK + +++L++K++ E+ IKD +
Sbjct: 122 LQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTI 181
Query: 507 XXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREF--GAFDNLNDVGNMINQQRDKL 564
+ Q+ + +L ++ + E +L + + +
Sbjct: 182 QEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVT 241
Query: 565 FELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNII 620
+ K E +EKLQ ++ E++ + +S+ +E + K +++++ +K EE ++
Sbjct: 242 IQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLL 297
>BC056146-1|AAH56146.1| 718|Homo sapiens hook homolog 3
(Drosophila) protein.
Length = 718
Score = 48.4 bits (110), Expect = 9e-05
Identities = 86/447 (19%), Positives = 179/447 (40%), Gaps = 36/447 (8%)
Query: 167 ISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELS 226
I + L +I E +ND L + D+ ++ + D ID LR ++++ L+ + +
Sbjct: 270 IRCEELEKEISELRQQNDELTTLADEAQS-----LKDEIDVLRHSSDKVSKLEGQVESYK 324
Query: 227 CALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQL 286
L DL ++R+Q+ + +N + + A QL
Sbjct: 325 KKLEDLG----DLRRQVKLLEEKNTMYMQNTVSLEEELR------------KANAARSQL 368
Query: 287 KTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHL 346
+T +VV+L+ L + ++ L+ ++ D+ L S+K+ L
Sbjct: 369 ETYKRQVVELQNRLSEESKKADKLDFEYKRLKEKVDSLQKEKDR-LRTERDSLKETIEEL 427
Query: 347 EDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIA---KLIEIEKKYNDSI 403
+ +L + + + + E + + K++++ ++ +D+
Sbjct: 428 RCVQAQEGQLTTQGLMPLGSQESSDSLAAEIVTPEIREKLIRLQHENKMLKLNQEGSDN- 486
Query: 404 EEKKTLQENIDD--LRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHR 461
E+ LQ +DD LR + LE+E R+ + + L E +S +E Q ++ S D
Sbjct: 487 EKIALLQSLLDDANLRKNELETENRLVN--QRLLEVQSQVEELQKSLQDQGSKAEDSVLL 544
Query: 462 KTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRE 521
K ++EE+ L E +EL+ K + + ++ E
Sbjct: 545 KKKLEEHLEKLHEAN---NELQKKRAIIEDLEPRFNNSSLKIEELQEALRKKEEEMKQME 601
Query: 522 SQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTK 581
+ K Y E+ ++ + + GA + + N + Q+RD+LF ++EY++ +
Sbjct: 602 ERYKKYLEKAKSVIRTLDPKQNQGAAPEIQALKNQL-QERDRLFH--SLEKEYEKTKSQR 658
Query: 582 ENEIKRLVESMTEQEHVLNKKEKEIKM 608
E E K +V + L+KK E ++
Sbjct: 659 EMEEKYIVSAWYNMGMTLHKKAAEDRL 685
Score = 39.9 bits (89), Expect = 0.030
Identities = 72/350 (20%), Positives = 149/350 (42%), Gaps = 42/350 (12%)
Query: 292 RVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIAL 351
R +QL+ LEQ + E++ LE E+ ++E+++L Q + TT ++
Sbjct: 243 RHLQLQTQLEQLQEETFRLE----AAKDDYRIRCEELEKEISELRQQNDELTTLADEAQS 298
Query: 352 AREKLQSXXXXXXXXXXXXS--ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTL 409
++++ SY K ++D+ ++ + +++ +EEK T+
Sbjct: 299 LKDEIDVLRHSSDKVSKLEGQVESYKKKLEDLG-----DLRRQVKL-------LEEKNTM 346
Query: 410 QENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIE-EY 468
T LE ELR + R S LET + EL++ ++ + +++ EY
Sbjct: 347 YMQ----NTVSLEEELRKANAAR------SQLETYKRQVVELQNRLSEESKKADKLDFEY 396
Query: 469 KRLLFEKGEEIDELKSKLSTEK-AIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSY 527
KRL EK + + + K +L TE+ ++K+ +ES S
Sbjct: 397 KRLK-EKVDSLQKEKDRLRTERDSLKETIEELRCVQAQEGQLTTQGLMPLGSQESS-DSL 454
Query: 528 YEELM--NLKNQITQLREFGAFDNLNDVGN------MINQQRDKLFELTKRQEEYDEKLQ 579
E++ ++ ++ +L+ LN G+ ++ D L K + E + +L
Sbjct: 455 AAEIVTPEIREKLIRLQHENKMLKLNQEGSDNEKIALLQSLLDDA-NLRKNELETENRLV 513
Query: 580 TKE-NEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
+ E++ VE + + K ++ +L +K EEH+ ++ +N+L+
Sbjct: 514 NQRLLEVQSQVEELQKSLQDQGSKAEDSVLLKKKLEEHLEKLHEANNELQ 563
Score = 37.9 bits (84), Expect = 0.12
Identities = 74/379 (19%), Positives = 154/379 (40%), Gaps = 45/379 (11%)
Query: 327 DFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMN 386
D D++L K T+ + + + E+IA +L A ++ + +
Sbjct: 173 DLDRQLKKTTEELNEALSAKEEIAQRCHELDMQVAALQEEKSSLLAENQVLMERLNQSDS 232
Query: 387 LNI------AKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESI 440
+ + ++++ + EE L+ DD R E E + +L ++ DE ++
Sbjct: 233 IEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKDDYRIRCEELEKEISELRQQNDELTTL 292
Query: 441 LETKQCVQKE---LESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXX 497
+ Q ++ E L + + + ++E YK+ L E++ +L+ + +K +
Sbjct: 293 ADEAQSLKDEIDVLRHSSDKVSKLEGQVESYKKKL----EDLGDLR------RQVKLLEE 342
Query: 498 XXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMI 557
R SQ+++Y +++ L+N++++ E D L+ +
Sbjct: 343 KNTMYMQNTVSLEEELRKANAAR-SQLETYKRQVVELQNRLSE--ESKKADKLDFEYKRL 399
Query: 558 NQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESM-----------TEQEHVLNKKEKEI 606
++ D L Q+E D +L+T+ + +K +E + T+ L +E
Sbjct: 400 KEKVDSL------QKEKD-RLRTERDSLKETIEELRCVQAQEGQLTTQGLMPLGSQESSD 452
Query: 607 KMLNE--KEEEHMNIINLLH-NK-LELRNE-ADIDVIITLAKYKKSLTLVLEKMSISNRV 661
+ E E +I L H NK L+L E +D + I L L ++ NR+
Sbjct: 453 SLAAEIVTPEIREKLIRLQHENKMLKLNQEGSDNEKIALLQSLLDDANLRKNELETENRL 512
Query: 662 LKCSLLGVVTQSRTLRKNM 680
+ LL V +Q L+K++
Sbjct: 513 VNQRLLEVQSQVEELQKSL 531
>BC039317-1|AAH39317.2| 484|Homo sapiens coiled-coil domain
containing 65 protein.
Length = 484
Score = 48.4 bits (110), Expect = 9e-05
Identities = 56/212 (26%), Positives = 97/212 (45%), Gaps = 13/212 (6%)
Query: 38 KTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVA 97
K ++ V EKS KE+E + ++ +L ++ + K+ + ++ E +I N
Sbjct: 241 KAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRE---SEDENRYIRNDK 297
Query: 98 KLSPEQLLQLCA-GGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINW 156
+L QL +L A + +A L ++T + N L +VDK E+ L K EI
Sbjct: 298 ELVLVQLRKLKAQRTQARAASQKNL-VRLTLESNATLKALRKIVDKGEKIL-KLAEICRK 355
Query: 157 FESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDII--DCLRKNANE 214
FE+ +EK + + + KE + + K++L++L E K + D I + K N+
Sbjct: 356 FET--EEEKVLPFYSSVLTPKE---QEGIQKNNLEELTEELTKVMVDYIGMENFWKRYNK 410
Query: 215 TMALQLRTKELSCALSDLNTQNAEMRKQIHSG 246
QL + L D+N + EM KQ G
Sbjct: 411 VKLEQLSLQHRRAQLLDINGKLREMLKQYLDG 442
>AK093051-1|BAC04035.1| 484|Homo sapiens protein ( Homo sapiens
cDNA FLJ35732 fis, clone TESTI2003141. ).
Length = 484
Score = 48.4 bits (110), Expect = 9e-05
Identities = 56/212 (26%), Positives = 97/212 (45%), Gaps = 13/212 (6%)
Query: 38 KTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVA 97
K ++ V EKS KE+E + ++ +L ++ + K+ + ++ E +I N
Sbjct: 241 KAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRE---SEDENRYIRNDK 297
Query: 98 KLSPEQLLQLCA-GGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINW 156
+L QL +L A + +A L ++T + N L +VDK E+ L K EI
Sbjct: 298 ELVLVQLRKLKAQRTQARAASQKNL-VRLTLESNATLKALRKIVDKGEKIL-KLAEICRK 355
Query: 157 FESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDII--DCLRKNANE 214
FE+ +EK + + + KE + + K++L++L E K + D I + K N+
Sbjct: 356 FET--EEEKVLPFYSSVLTPKE---QEGIQKNNLEELTEELTKVMVDYIGMENFWKRYNK 410
Query: 215 TMALQLRTKELSCALSDLNTQNAEMRKQIHSG 246
QL + L D+N + EM KQ G
Sbjct: 411 VKLEQLSLQHRRAQLLDINGKLREMLKQYLDG 442
>AF241830-1|AAK29204.1| 718|Homo sapiens golgi-associated
microtubule-binding protein HOOK3 protein.
Length = 718
Score = 48.4 bits (110), Expect = 9e-05
Identities = 86/447 (19%), Positives = 179/447 (40%), Gaps = 36/447 (8%)
Query: 167 ISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELS 226
I + L +I E +ND L + D+ ++ + D ID LR ++++ L+ + +
Sbjct: 270 IRCEELEKEISELRQQNDELTTLADEAQS-----LKDEIDVLRHSSDKVSKLEGQVESYK 324
Query: 227 CALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQL 286
L DL ++R+Q+ + +N + + A QL
Sbjct: 325 KKLEDLG----DLRRQVKLLEEKNTMYMQNTVSLEEELR------------KANAARSQL 368
Query: 287 KTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHL 346
+T +VV+L+ L + ++ L+ ++ D+ L S+K+ L
Sbjct: 369 ETYKRQVVELQNRLSEESKKADKLDFEYKRLKEKVDSLQKEKDR-LRTERDSLKETIEEL 427
Query: 347 EDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIA---KLIEIEKKYNDSI 403
+ +L + + + + E + + K++++ ++ +D+
Sbjct: 428 RCVQAQEGQLTTQGLMPLGSQESSDSLAAEIVTPEIREKLIRLQHENKMLKLNQEGSDN- 486
Query: 404 EEKKTLQENIDD--LRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHR 461
E+ LQ +DD LR + LE+E R+ + + L E +S +E Q ++ S D
Sbjct: 487 EKIALLQSLLDDANLRKNELETENRLVN--QRLLEVQSQVEELQKSLQDQGSKAEDSVLL 544
Query: 462 KTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRE 521
K ++EE+ L E +EL+ K + + ++ E
Sbjct: 545 KKKLEEHLEKLHEAN---NELQKKRAIIEDLEPRFNNSSLKIEELQEALRKKEEEMKQME 601
Query: 522 SQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTK 581
+ K Y E+ ++ + + GA + + N + Q+RD+LF ++EY++ +
Sbjct: 602 ERYKKYLEKAKSVIRTLDPKQNQGAAPEIQALKNQL-QERDRLFH--SLEKEYEKTKSQR 658
Query: 582 ENEIKRLVESMTEQEHVLNKKEKEIKM 608
E E K +V + L+KK E ++
Sbjct: 659 EMEEKYIVSAWYNMGMTLHKKAAEDRL 685
Score = 39.9 bits (89), Expect = 0.030
Identities = 72/350 (20%), Positives = 149/350 (42%), Gaps = 42/350 (12%)
Query: 292 RVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIAL 351
R +QL+ LEQ + E++ LE E+ ++E+++L Q + TT ++
Sbjct: 243 RHLQLQTQLEQLQEETFRLE----AAKDDYRIRCEELEKEISELRQQNDELTTLADEAQS 298
Query: 352 AREKLQSXXXXXXXXXXXXS--ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTL 409
++++ SY K ++D+ ++ + +++ +EEK T+
Sbjct: 299 LKDEIDVLRHSSDKVSKLEGQVESYKKKLEDLG-----DLRRQVKL-------LEEKNTM 346
Query: 410 QENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIE-EY 468
T LE ELR + R S LET + EL++ ++ + +++ EY
Sbjct: 347 YMQ----NTVSLEEELRKANAAR------SQLETYKRQVVELQNRLSEESKKADKLDFEY 396
Query: 469 KRLLFEKGEEIDELKSKLSTEK-AIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSY 527
KRL EK + + + K +L TE+ ++K+ +ES S
Sbjct: 397 KRLK-EKVDSLQKEKDRLRTERDSLKETIEELRCVQAQEGQLTTQGLMPLGSQESS-DSL 454
Query: 528 YEELM--NLKNQITQLREFGAFDNLNDVGN------MINQQRDKLFELTKRQEEYDEKLQ 579
E++ ++ ++ +L+ LN G+ ++ D L K + E + +L
Sbjct: 455 AAEIVTPEIREKLIRLQHENKMLKLNQEGSDNEKIALLQSLLDDA-NLRKNELETENRLV 513
Query: 580 TKE-NEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
+ E++ VE + + K ++ +L +K EEH+ ++ +N+L+
Sbjct: 514 NQRLLEVQSQVEELQKSLQDQGSKAEDSVLLKKKLEEHLEKLHEANNELQ 563
Score = 37.9 bits (84), Expect = 0.12
Identities = 74/379 (19%), Positives = 154/379 (40%), Gaps = 45/379 (11%)
Query: 327 DFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMN 386
D D++L K T+ + + + E+IA +L A ++ + +
Sbjct: 173 DLDRQLKKTTEELNEALSAKEEIAQRCHELDMQVAALQEEKSSLLAENQVLMERLNQSDS 232
Query: 387 LNI------AKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESI 440
+ + ++++ + EE L+ DD R E E + +L ++ DE ++
Sbjct: 233 IEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKDDYRIRCEELEKEISELRQQNDELTTL 292
Query: 441 LETKQCVQKE---LESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXX 497
+ Q ++ E L + + + ++E YK+ L E++ +L+ + +K +
Sbjct: 293 ADEAQSLKDEIDVLRHSSDKVSKLEGQVESYKKKL----EDLGDLR------RQVKLLEE 342
Query: 498 XXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMI 557
R SQ+++Y +++ L+N++++ E D L+ +
Sbjct: 343 KNTMYMQNTVSLEEELRKANAAR-SQLETYKRQVVELQNRLSE--ESKKADKLDFEYKRL 399
Query: 558 NQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESM-----------TEQEHVLNKKEKEI 606
++ D L Q+E D +L+T+ + +K +E + T+ L +E
Sbjct: 400 KEKVDSL------QKEKD-RLRTERDSLKETIEELRCVQAQEGQLTTQGLMPLGSQESSD 452
Query: 607 KMLNE--KEEEHMNIINLLH-NK-LELRNE-ADIDVIITLAKYKKSLTLVLEKMSISNRV 661
+ E E +I L H NK L+L E +D + I L L ++ NR+
Sbjct: 453 SLAAEIVTPEIREKLIRLQHENKMLKLNQEGSDNEKIALLQSLLDDANLRKNELETENRL 512
Query: 662 LKCSLLGVVTQSRTLRKNM 680
+ LL V +Q L+K++
Sbjct: 513 VNQRLLEVQSQVEELQKSL 531
>Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heavy
chain protein.
Length = 1939
Score = 48.0 bits (109), Expect = 1e-04
Identities = 51/288 (17%), Positives = 124/288 (43%), Gaps = 6/288 (2%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLV 431
A+ + +K + + A+ E+E+K ++EK LQ + + +L ++E R L+
Sbjct: 852 ATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLI 911
Query: 432 RELDEKES-ILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEK 490
+ + E+ + E + ++ E E +L +K ++E+ L + ++++ +K+ EK
Sbjct: 912 KNKIQLEAKVKEMNERLEDE-EEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 970
Query: 491 -AIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQL--REFGAF 547
A ++ + + ++L ++++ L +
Sbjct: 971 HATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLE 1030
Query: 548 DNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK 607
++D+ + Q++ +L + + + + L+ + I L + E L KKE +I
Sbjct: 1031 QQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDIN 1090
Query: 608 MLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKM 655
N K E+ + L KL+ N+A I+ + + +++ +EK+
Sbjct: 1091 QQNSKIEDEQALALQLQKKLK-ENQARIEELEEELEAERTARAKVEKL 1137
Score = 41.1 bits (92), Expect = 0.013
Identities = 66/447 (14%), Positives = 169/447 (37%), Gaps = 17/447 (3%)
Query: 175 KIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNT 234
+IKE +++ + L++ L+E ND+ ++ + + R +L L
Sbjct: 860 RIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEA 919
Query: 235 QNAEMRKQIHSGDHHRPY--ANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVER 292
+ EM +++ + A + + ++ + +H + V+
Sbjct: 920 KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 979
Query: 293 VVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQS---IKDNTTHLEDI 349
+ + A L++ ++ ++ + + + ++N L++S ++ LE
Sbjct: 980 LTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGS 1039
Query: 350 ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTL 409
+K++ +SI D++++ +++E+K +
Sbjct: 1040 LEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDK-------LQLEEKLKKKEFDINQQ 1092
Query: 410 QENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYK 469
I+D + L+ + ++K+ ++E E LE ++ + ++E ++DL EI E
Sbjct: 1093 NSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISE-- 1150
Query: 470 RLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYE 529
RL G +++ E + + +++ +
Sbjct: 1151 RLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQID 1210
Query: 530 ELMNLKNQITQLR-EFG-AFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKR 587
L +K ++ + + EF D++ I + + L ++++ E+ + + K E +R
Sbjct: 1211 NLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQR 1270
Query: 588 LVESMTEQEHVLNKKEKEI-KMLNEKE 613
+ T Q L + E+ + L EKE
Sbjct: 1271 SLNDFTTQRAKLQTENGELARQLEEKE 1297
Score = 37.5 bits (83), Expect = 0.16
Identities = 86/488 (17%), Positives = 186/488 (38%), Gaps = 38/488 (7%)
Query: 22 NEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQ 81
+ Q+ S S ++ KLK ++E + E K+E ++ Q ++ +L L + + L +
Sbjct: 1471 SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEK 1530
Query: 82 KVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVD 141
E+L + + + + L E K L N++ ++ + L + +
Sbjct: 1531 VRKQLEVEKLELQSALEEAEASL----EHEEGKILRAQLEFNQIKAEIERKLAEKD---E 1583
Query: 142 KCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIK---EFNAENDLLKSSLDQLRTEFL 198
+ E+ + +++ ++ + E + L +K K + N E ++ S +++ E
Sbjct: 1584 EMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLN-EMEIQLSHANRMAAEAQ 1642
Query: 199 KEINDIIDCLRK---------NANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHH 249
K++ + L+ AN+ + + E L L + E+R + +
Sbjct: 1643 KQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNL--LQAELEELRAVVEQTERS 1700
Query: 250 RPYANRNXXXXXXXXXXXXXXXXSIM--KDRLSRAEHQLKTNVERVVQLEAALEQARSES 307
R A + S++ K ++ QL++ VE VQ E+ ++
Sbjct: 1701 RKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKA 1760
Query: 308 WSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHL---EDIAL--AREKLQSXXXX 362
+ + ++ + Q+IKD L E IAL +++LQ
Sbjct: 1761 ITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEAR 1820
Query: 363 XXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLE 422
A ++ + +K M + ++ E+ + + + LQ+ +D L
Sbjct: 1821 VRELEGELEAEQKRNAESVK-GMRKSERRIKELTYQTEEDKKNLLRLQDLVDKL------ 1873
Query: 423 SELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDEL 482
+L+VK R+ +E E T ++++ + E R E L K +I
Sbjct: 1874 -QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIG-A 1931
Query: 483 KSKLSTEK 490
K K+ E+
Sbjct: 1932 KQKMHDEE 1939
Score = 33.9 bits (74), Expect = 2.0
Identities = 63/352 (17%), Positives = 139/352 (39%), Gaps = 22/352 (6%)
Query: 334 KLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLI 393
K S+ + ++++ ++KL+ +++ + IK K + L
Sbjct: 1197 KHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIK-AKANLEKVSRTLE 1255
Query: 394 EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELES 453
+ +Y +EE Q +++D T + + +L R+L+EKE+++ Q + +L
Sbjct: 1256 DQANEYRVKLEEA---QRSLNDFTTQRAKLQTENGELARQLEEKEALI--SQLTRGKLSY 1310
Query: 454 TKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXX 513
T+ ++E+ KR L E+G+ + L L + + D+
Sbjct: 1311 TQ--------QMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRV 1362
Query: 514 XXXXXXRESQMKSYYE-ELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQE 572
+Q ++ YE + + ++ + ++ A L D + K L K +
Sbjct: 1363 LSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA-QRLQDAEEAVEAVNAKCSSLEKTK- 1420
Query: 573 EYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEI-KMLNEKEEEHMNIINLLHNKLELRN 631
+LQ + ++ VE L+KK++ K+L E ++++ + L + +
Sbjct: 1421 ---HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEAR 1477
Query: 632 EADIDVIITLAKYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRTLRKNMSGL 683
++ Y++SL LE N+ L+ + + Q KN+ L
Sbjct: 1478 SLSTELFKLKNAYEESLE-HLETFKRENKNLQEEISDLTEQLGEGGKNVHEL 1528
>M81105-1|AAA59888.1| 1337|Homo sapiens cellular myosin heavy chain
protein.
Length = 1337
Score = 48.0 bits (109), Expect = 1e-04
Identities = 56/283 (19%), Positives = 121/283 (42%), Gaps = 15/283 (5%)
Query: 382 KHE-MNLNIAKLIEIEKKYNDSIEE-KKTLQENIDDLRTDLLESELRVKDLVRELDEKES 439
KHE M ++ + + E+K +E+ ++ L+ + DL + E + ++ +L +L +KE
Sbjct: 1024 KHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEE 1083
Query: 440 ILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEID-ELKSKLSTEKAIKDIXXX 498
L+ + E E+ + ++ +K I E + + E E+++ E S+ EK +D+
Sbjct: 1084 ELQAA-LARVEEEAAQKNMALKK--IRELESQISELQEDLESERASRNKAEKQKRDLGEE 1140
Query: 499 XXXXXXXXXXXXXXXXXXXXXRESQ-------MKSYYEELMNLKNQITQLREFGAFDNLN 551
R + K+ EE + QI ++R+ + +
Sbjct: 1141 LEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHS-QAVE 1199
Query: 552 DVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNE 611
++ + Q + L K ++ + + NE+K L++ + EH K E +++ L
Sbjct: 1200 ELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQV 1259
Query: 612 KEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEK 654
K E + L +K+ + + ++D + L S + L K
Sbjct: 1260 KFNEGERVRTELADKV-TKLQVELDNVTGLLSQSDSKSSKLTK 1301
Score = 44.0 bits (99), Expect = 0.002
Identities = 70/384 (18%), Positives = 151/384 (39%), Gaps = 47/384 (12%)
Query: 274 IMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXE---DFDQ 330
+M ++L E QL+ E + E + ++ LE E
Sbjct: 878 LMAEKLQLQE-QLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQA 936
Query: 331 ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIA 390
E K+ Q+I++ LE+ AR+KLQ + +K ++ E
Sbjct: 937 EKKKMQQNIQELEEQLEEEESARQKLQ-----------LEKVTTEAKLKKLEEEQ----- 980
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKE 450
I +E + +EKK L++ I + T+L E E + K L + ++ E+++
Sbjct: 981 --IILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMI--------- 1029
Query: 451 LESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXX 510
TDLE R EE +R +E+++ + KL + D+
Sbjct: 1030 -----TDLEERLRR-EEKQR------QELEKTRRKLEGDST--DLSDQIAELQAQIAELK 1075
Query: 511 XXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKR 570
++ + EE + ++RE + ++++ + +R + K+
Sbjct: 1076 MQLAKKEEELQAALARVEEEAAQKNMALKKIRELES--QISELQEDLESERASRNKAEKQ 1133
Query: 571 QEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELR 630
+ + E+L+ + E++ ++S Q+ + +K+E+E+ +L + EE ++ +
Sbjct: 1134 KRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQK 1193
Query: 631 NEADIDVIITLAKYKKSLTLVLEK 654
+ ++ + + K + LEK
Sbjct: 1194 HSQAVEELAEQLEQTKRVKANLEK 1217
Score = 37.1 bits (82), Expect = 0.21
Identities = 61/337 (18%), Positives = 127/337 (37%), Gaps = 8/337 (2%)
Query: 158 ESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMA 217
E + +E+ + + + + E + L+S L + + +++ + +
Sbjct: 846 EMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRAR 905
Query: 218 LQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKD 277
L + +EL DL + E ++ + +N + +
Sbjct: 906 LTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLE 965
Query: 278 RLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQ 337
+++ E +LK E + LE + E LE + E+ + L KL
Sbjct: 966 KVT-TEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEE-EEKSKSLAKLKN 1023
Query: 338 SIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH---EMNLNIAKLIE 394
+ T LE+ EK + S + I +++ E+ + +AK E
Sbjct: 1024 KHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEE 1083
Query: 395 IEKKYNDSIEEKKTLQENIDDLRTDLLESELRV--KDLVRELDEKESILETKQCVQKELE 452
+ +EE+ Q+N+ + LES++ +DL E + + K+ + +ELE
Sbjct: 1084 ELQAALARVEEEAA-QKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELE 1142
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
+ KT+LE + L ++ +E++ LK L E
Sbjct: 1143 ALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEE 1179
Score = 33.9 bits (74), Expect = 2.0
Identities = 50/248 (20%), Positives = 97/248 (39%), Gaps = 8/248 (3%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLL--ESELRVKDLVRELDEKESILETKQCVQ 448
+L E+E + + EK LQE + T+L ELR + L + E E I +
Sbjct: 867 RLTEMETLQSQLMAEKLQLQEQL-QAETELCAEAEELRAR-LTAKKQELEEICHDLEARV 924
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXX 508
+E E L+ K ++++ + L E+ EE + + KL EK +
Sbjct: 925 EEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILE 984
Query: 509 XXX-XXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDN--LNDVGNMINQQRDKLF 565
E ++ + L + + L + + D+ + ++ +
Sbjct: 985 DQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQ 1044
Query: 566 ELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHN 625
EL K + + + ++I L + E + L KKE+E++ + EE N+
Sbjct: 1045 ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALK 1104
Query: 626 KL-ELRNE 632
K+ EL ++
Sbjct: 1105 KIRELESQ 1112
Score = 33.5 bits (73), Expect = 2.6
Identities = 48/194 (24%), Positives = 80/194 (41%), Gaps = 13/194 (6%)
Query: 4 EELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQ-V 62
EELE + + + L +QE + ++ LK +E+ T E +E+ + +Q V
Sbjct: 1139 EELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAV 1198
Query: 63 MELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLD 122
EL L T R L + E + N K+ LLQ E K +
Sbjct: 1199 EELAEQLEQTKRVKANLEKAKQTLENERGELANEVKV----LLQGKGDSEHKRKKVEAQL 1254
Query: 123 NKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAE 182
++ N+ + L DK + + E+ N L+SQ S+K LT K+F+A
Sbjct: 1255 QELQVKFNEGERVRTELADKVTKL---QVELDN-VTGLLSQSDSKSSK-LT---KDFSAL 1306
Query: 183 NDLLKSSLDQLRTE 196
L+ + + L+ E
Sbjct: 1307 ESQLQDTQELLQEE 1320
>BC049849-1|AAH49849.1| 1374|Homo sapiens Unknown (protein for
IMAGE:5563109) protein.
Length = 1374
Score = 48.0 bits (109), Expect = 1e-04
Identities = 56/283 (19%), Positives = 121/283 (42%), Gaps = 15/283 (5%)
Query: 382 KHE-MNLNIAKLIEIEKKYNDSIEE-KKTLQENIDDLRTDLLESELRVKDLVRELDEKES 439
KHE M ++ + + E+K +E+ ++ L+ + DL + E + ++ +L +L +KE
Sbjct: 1024 KHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEE 1083
Query: 440 ILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEID-ELKSKLSTEKAIKDIXXX 498
L+ + E E+ + ++ +K I E + + E E+++ E S+ EK +D+
Sbjct: 1084 ELQAA-LARVEEEAAQKNMALKK--IRELESQISELQEDLESERASRNKAEKQKRDLGEE 1140
Query: 499 XXXXXXXXXXXXXXXXXXXXXRESQ-------MKSYYEELMNLKNQITQLREFGAFDNLN 551
R + K+ EE + QI ++R+ + +
Sbjct: 1141 LEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHS-QAVE 1199
Query: 552 DVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNE 611
++ + Q + L K ++ + + NE+K L++ + EH K E +++ L
Sbjct: 1200 ELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQV 1259
Query: 612 KEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEK 654
K E + L +K+ + + ++D + L S + L K
Sbjct: 1260 KFNEGERVRTELADKV-TKLQVELDNVTGLLSQSDSKSSKLTK 1301
Score = 44.0 bits (99), Expect = 0.002
Identities = 70/384 (18%), Positives = 151/384 (39%), Gaps = 47/384 (12%)
Query: 274 IMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXE---DFDQ 330
+M ++L E QL+ E + E + ++ LE E
Sbjct: 878 LMAEKLQLQE-QLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQA 936
Query: 331 ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIA 390
E K+ Q+I++ LE+ AR+KLQ + +K ++ E
Sbjct: 937 EKKKMQQNIQELEEQLEEEESARQKLQ-----------LEKVTTEAKLKKLEEEQ----- 980
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKE 450
I +E + +EKK L++ I + T+L E E + K L + ++ E+++
Sbjct: 981 --IILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMI--------- 1029
Query: 451 LESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXX 510
TDLE R EE +R +E+++ + KL + D+
Sbjct: 1030 -----TDLEERLRR-EEKQR------QELEKTRRKLEGDST--DLSDQIAELQAQIAELK 1075
Query: 511 XXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKR 570
++ + EE + ++RE + ++++ + +R + K+
Sbjct: 1076 MQLAKKEEELQAALARVEEEAAQKNMALKKIRELES--QISELQEDLESERASRNKAEKQ 1133
Query: 571 QEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELR 630
+ + E+L+ + E++ ++S Q+ + +K+E+E+ +L + EE ++ +
Sbjct: 1134 KRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQK 1193
Query: 631 NEADIDVIITLAKYKKSLTLVLEK 654
+ ++ + + K + LEK
Sbjct: 1194 HSQAVEELAEQLEQTKRVKANLEK 1217
Score = 37.1 bits (82), Expect = 0.21
Identities = 61/337 (18%), Positives = 127/337 (37%), Gaps = 8/337 (2%)
Query: 158 ESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMA 217
E + +E+ + + + + E + L+S L + + +++ + +
Sbjct: 846 EMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRAR 905
Query: 218 LQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKD 277
L + +EL DL + E ++ + +N + +
Sbjct: 906 LTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLE 965
Query: 278 RLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQ 337
+++ E +LK E + LE + E LE + E+ + L KL
Sbjct: 966 KVT-TEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEE-EEKSKSLAKLKN 1023
Query: 338 SIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH---EMNLNIAKLIE 394
+ T LE+ EK + S + I +++ E+ + +AK E
Sbjct: 1024 KHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEE 1083
Query: 395 IEKKYNDSIEEKKTLQENIDDLRTDLLESELRV--KDLVRELDEKESILETKQCVQKELE 452
+ +EE+ Q+N+ + LES++ +DL E + + K+ + +ELE
Sbjct: 1084 ELQAALARVEEEAA-QKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELE 1142
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
+ KT+LE + L ++ +E++ LK L E
Sbjct: 1143 ALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEE 1179
Score = 36.7 bits (81), Expect = 0.28
Identities = 56/241 (23%), Positives = 103/241 (42%), Gaps = 14/241 (5%)
Query: 4 EELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQ-V 62
EELE + + + L +QE + ++ LK +E+ T E +E+ + +Q V
Sbjct: 1139 EELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAV 1198
Query: 63 MELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLD 122
EL L T R L + E + N K+ LLQ E K +
Sbjct: 1199 EELAEQLEQTKRVKANLEKAKQTLENERGELANEVKV----LLQGKGDSEHKRKKVEAQL 1254
Query: 123 NKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAE 182
++ N+ + L DK + + E+ N L+SQ S+K LT K+F+A
Sbjct: 1255 QELQVKFNEGERVRTELADKVTKL---QVELDN-VTGLLSQSDSKSSK-LT---KDFSAL 1306
Query: 183 NDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQ 242
L+ + + L+ E ++++ + L++ +E + + + +E A +L Q A + Q
Sbjct: 1307 ESQLQDTQELLQEENRQKLS-LSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQ 1365
Query: 243 I 243
+
Sbjct: 1366 V 1366
Score = 33.9 bits (74), Expect = 2.0
Identities = 50/248 (20%), Positives = 97/248 (39%), Gaps = 8/248 (3%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLL--ESELRVKDLVRELDEKESILETKQCVQ 448
+L E+E + + EK LQE + T+L ELR + L + E E I +
Sbjct: 867 RLTEMETLQSQLMAEKLQLQEQL-QAETELCAEAEELRAR-LTAKKQELEEICHDLEARV 924
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXX 508
+E E L+ K ++++ + L E+ EE + + KL EK +
Sbjct: 925 EEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILE 984
Query: 509 XXX-XXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDN--LNDVGNMINQQRDKLF 565
E ++ + L + + L + + D+ + ++ +
Sbjct: 985 DQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQ 1044
Query: 566 ELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHN 625
EL K + + + ++I L + E + L KKE+E++ + EE N+
Sbjct: 1045 ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALK 1104
Query: 626 KL-ELRNE 632
K+ EL ++
Sbjct: 1105 KIRELESQ 1112
>BC028423-1|AAH28423.1| 1022|Homo sapiens PMFBP1 protein protein.
Length = 1022
Score = 48.0 bits (109), Expect = 1e-04
Identities = 84/481 (17%), Positives = 185/481 (38%), Gaps = 39/481 (8%)
Query: 169 TKTLTMKIKEFNAENDL----LKSSLDQLRTEFLKEINDII--DCLRKNANETM--ALQL 220
T+ LT+K +F E D L+ L Q++ LK+ ++ C+ T+ A Q
Sbjct: 392 TQKLTLKKDKFLQEKDEMLQELEKKLTQVQNSLLKKEKELEKQQCMATELEMTVKEAKQD 451
Query: 221 RTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSI-MKDRL 279
++KE C Q +++ + A ++D
Sbjct: 452 KSKEAECKALQAEVQ--KLKNSLEEAKQQERLAGEAPAAQQAAQCKEEAALAGCHLEDTQ 509
Query: 280 SRAEHQL---KTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLT 336
+ + L K + + +L+ L+ + ES E+ + + L KL
Sbjct: 510 RKLQKGLLLDKQKADTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLELSEALRKLE 569
Query: 337 QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIE 396
S K+ + +A K+ + K +D++ L K +++
Sbjct: 570 NSDKEKRQLQKTVAEQDMKMNDMLDRIKHQHREQGSIKCKLEEDLQEATKLLEDKREQLK 629
Query: 397 KKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETK-QCVQKELESTK 455
K S E +K ++ ++ LR + + + +K+ R+L+E+ L + QC +LES+
Sbjct: 630 K----SKEHEKLMEGELEALRQEFKKKDKTLKENSRKLEEENENLRAELQCCSTQLESSL 685
Query: 456 TDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXX 515
+ I++ + + + E + L+++L +KA++
Sbjct: 686 NKYNTSQQVIQDLNKEIALQKESLMSLQAQL--DKALQ--KEKHYLQTTITKEAYDALSR 741
Query: 516 XXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYD 575
+ + E+L ++ ++ L++ + Q ++K +L + Y+
Sbjct: 742 KSAACQDDLTQALEKLNHVTSETKSLQQ------------SLTQTQEKKAQLEEEIIAYE 789
Query: 576 EKLQTKENEIKRLVESMTEQE---HVLNKKEKEIK-MLNEKEEEHMNIINLLHNKLELRN 631
E+++ E+++L E E H +KK +E+ + + +++H N + +L K E
Sbjct: 790 ERMKKLNTELRKLRGFHQESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLR 849
Query: 632 E 632
E
Sbjct: 850 E 850
Score = 42.7 bits (96), Expect = 0.004
Identities = 52/275 (18%), Positives = 110/275 (40%), Gaps = 12/275 (4%)
Query: 339 IKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKK 398
+KD LE ++ + + + I+ ++ + +L E++ +
Sbjct: 329 VKDLRVELEAVSEQKRNIMKDMMKLELDLHGLREETSAHIERKDKDITILQCRLQELQLE 388
Query: 399 YNDSIEEKKTLQEN--IDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKT 456
+ ++ +K TL+++ + + L E E ++ + L +KE LE +QC+ ELE T
Sbjct: 389 FTET--QKLTLKKDKFLQEKDEMLQELEKKLTQVQNSLLKKEKELEKQQCMATELEMTVK 446
Query: 457 DLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXX 516
+ + K++ E K L E+ +LK+ L K + +
Sbjct: 447 EAKQDKSKEAECKAL----QAEVQKLKNSLEEAKQQERLAGEAPAAQQAAQCKEEAALAG 502
Query: 517 XXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQ----RDKLFELTKRQE 572
++Q K L++ + T L +M ++ R ++ EL+
Sbjct: 503 CHLEDTQRKLQKGLLLDKQKADTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLELS 562
Query: 573 EYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK 607
E KL+ + E ++L +++ EQ+ +N IK
Sbjct: 563 EALRKLENSDKEKRQLQKTVAEQDMKMNDMLDRIK 597
>AY368076-1|AAR04774.1| 1674|Homo sapiens kinesin family member 21A
protein.
Length = 1674
Score = 48.0 bits (109), Expect = 1e-04
Identities = 57/238 (23%), Positives = 105/238 (44%), Gaps = 14/238 (5%)
Query: 387 LNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDL-LESELRVKDLVRELDEKESILETKQ 445
+++AK ++EK +KK LQ+ + R + + + D +E E++ + E ++
Sbjct: 538 IDLAKK-DLEKLKRKEKRKKKRLQKLEESNREERSVAGKEDNTDTDQEKKEEKGVSE-RE 595
Query: 446 CVQKELESTKTDLEHR-KTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXX 504
+ E+E ++ +H + E EE + + GE DE S+ S EKA
Sbjct: 596 NNELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSE-SDEKANYQADLANITCEI 654
Query: 505 XXXXXXXXXXXXXXXRESQMKSYYEE-LMNLKNQI--TQLREFGAFDNLNDVGNMINQQR 561
R +K YEE LM L+++I TQL NL V + ++
Sbjct: 655 AIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKA 714
Query: 562 DKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNI 619
K+ + EY++KLQ E++RL + E +L + + K L + +++ M +
Sbjct: 715 KKV------RSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEM 766
Score = 35.5 bits (78), Expect = 0.65
Identities = 58/327 (17%), Positives = 126/327 (38%), Gaps = 19/327 (5%)
Query: 172 LTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRT-----KELS 226
L ++IK D L+S + QL ++ + N ++ NE ++ + + ++L
Sbjct: 435 LRVRIKAMQETVDALRSRITQLVSD---QANHVL-ARAGEGNEEISNMIHSYIKEIEDLR 490
Query: 227 CALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSI--MKDRLSRAEH 284
L + N +RK + PY + + I K L + +
Sbjct: 491 AKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDLAKKDLEKLKR 550
Query: 285 QLKTNVERVVQLEAALEQARSESWSLERT-VXXXXXXXXXXXEDFDQELN-KLTQSIKDN 342
+ K +R+ +LE + + RS + + T E + EL + +Q + D+
Sbjct: 551 KEKRKKKRLQKLEESNREERSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDH 610
Query: 343 TTHLEDIALAREKLQSXXXXXXXXXXXXS-ASYNKSIKDMKHEMNLNIAKLIEIEKKYND 401
E+ + + A+Y + ++ E+ + + E+E
Sbjct: 611 EDEEEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKR 670
Query: 402 SIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETK-----QCVQKELESTKT 456
KK +E + L+ + +++L +++ L ES E K +K+L++
Sbjct: 671 LQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNK 730
Query: 457 DLEHRKTEIEEYKRLLFEKGEEIDELK 483
+L+ + +E+ RLL + + +LK
Sbjct: 731 ELQRLQAAQKEHARLLKNQSQYEKQLK 757
>AK098529-1|BAC05324.1| 302|Homo sapiens protein ( Homo sapiens
cDNA FLJ25663 fis, clone TST01640. ).
Length = 302
Score = 48.0 bits (109), Expect = 1e-04
Identities = 56/212 (26%), Positives = 97/212 (45%), Gaps = 13/212 (6%)
Query: 38 KTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVA 97
K ++ V EKS KE+E + ++ +L ++ + K+ + ++ E +I N
Sbjct: 46 KAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRE---SEDENRYIRNDK 102
Query: 98 KLSPEQLLQLCA-GGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINW 156
+L QL +L A + +A L ++T + N L +VDK E+ L K EI
Sbjct: 103 ELVLVQLRKLEAQRTQARAASQKNL-VRLTLESNATLKALRKIVDKGEKIL-KLAEICRK 160
Query: 157 FESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDII--DCLRKNANE 214
FE+ +EK + + + KE + + K++L++L E K + D I + K N+
Sbjct: 161 FET--EEEKVLPFYSSVLTPKE---QEGIQKNNLEELTEELTKVMVDYIGMENFWKRYNK 215
Query: 215 TMALQLRTKELSCALSDLNTQNAEMRKQIHSG 246
QL + L D+N + EM KQ G
Sbjct: 216 VKLEQLSLQHRRAQLLDINGKLREMLKQYLDG 247
>AK027863-1|BAB55415.1| 612|Homo sapiens protein ( Homo sapiens
cDNA FLJ14957 fis, clone PLACE4000009, weakly similar to
MYOSIN HEAVY CHAIN, NONMUSCLE TYPE B. ).
Length = 612
Score = 48.0 bits (109), Expect = 1e-04
Identities = 97/540 (17%), Positives = 211/540 (39%), Gaps = 43/540 (7%)
Query: 144 EETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEIND 203
E+ L KR+ + + + +E + + ++++AE L+ S++ E K +
Sbjct: 60 EDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVE----EATKNVEV 115
Query: 204 IIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXX 263
+ + + ++R K L L ++ E+ +++ +
Sbjct: 116 LASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKET 175
Query: 264 XXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXX 323
+ ++ L + K V LE LE A+ +L +T
Sbjct: 176 LKKYEGEIRQL-EEALVHVRKEEKEAVSARRALENELEAAQG---NLSQTTQEQKQLSEK 231
Query: 324 XXEDFDQ--ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDM 381
E+ +Q +L +L +++ HL EKLQ + + +
Sbjct: 232 LKEESEQKEQLRRLKNEMENERWHLGKTI---EKLQKEMADIVEASRTSTLELQNQLDEY 288
Query: 382 KHEMNLNIAKLI-EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESI 440
K + +A++ ++++K ++ + + T + D +R L+E ELR D R DE
Sbjct: 289 KEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDGMR--LMEEELR--DYQRAQDEA--- 341
Query: 441 LETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXX 500
L +Q +++ L+ + +LE + ++ RL+ + +++ +L+ +L E+ D+
Sbjct: 342 LTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLTERI 401
Query: 501 XXXXXXXXXXXXXXXXXXXRESQMK----SYYEELMNLKNQITQLREFGAFDNLNDVGNM 556
++ S + +LK++I L G++ + + +
Sbjct: 402 SRSREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLE--GSYRSSKE--GL 457
Query: 557 INQQRDKLFELTKR--QEEYDE-KLQTKENEIKRLVE-----------SMTEQEHVLNKK 602
+ Q ++ EL R EE D LQ ++R V+ S+T+Q+ L+ +
Sbjct: 458 VVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLR 517
Query: 603 EKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVL 662
K +K E+ EE ++ + KL+ E +D+ L S+ L + ++VL
Sbjct: 518 LKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPSKVL 577
>X51592-1|CAA35941.1| 1437|Homo sapiens fetal-myosin heavy chain
(1437 AA) protein.
Length = 1437
Score = 47.6 bits (108), Expect = 2e-04
Identities = 59/285 (20%), Positives = 129/285 (45%), Gaps = 30/285 (10%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLV 431
A+ + + K E+ + AK E+E+K ++EK LQ + L ++E R + L+
Sbjct: 352 ATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLI 411
Query: 432 RELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
+ + E+ ++ +E E +L +K ++E+ E ++ID+L +L+ K
Sbjct: 412 KNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDE---CSELKKDIDDL--ELTLAKV 466
Query: 492 IKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQL-REFGAFDNL 550
K+ E+++K+ EE+ L I +L +E A
Sbjct: 467 EKE----------------------KHATENKVKNLTEEMAGLDETIAKLSKEKKALQET 504
Query: 551 N-DVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKML 609
+ + + + DK+ LTK + + ++++ E +++ + + E K E ++K+
Sbjct: 505 HQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLA 564
Query: 610 NEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEK 654
E ++ N L KLE + E +I +I+ + ++++ + L+K
Sbjct: 565 QESTMDNENDKQQLDEKLE-KKEFEISNLISKIEDEQAVEIQLQK 608
Score = 47.2 bits (107), Expect = 2e-04
Identities = 68/381 (17%), Positives = 158/381 (41%), Gaps = 25/381 (6%)
Query: 277 DRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLT 336
++L + + QL+ ++ V + E+ +E + +R + +D + L K+
Sbjct: 408 EQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 467
Query: 337 QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHE---MNLNIAKLI 393
+ ++++ L ++ +++ D++ E +N+
Sbjct: 468 KEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKT 527
Query: 394 EIEKKYND---SIEEKKTLQENID----DLRTDLL---ESELRVKDLVRELDEK--ESIL 441
++E++ +D S+E++K L+ +++ L DL ES + ++ ++LDEK +
Sbjct: 528 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDNENDKQQLDEKLEKKEF 587
Query: 442 ETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEID-ELKSKLSTEKAIKDIXXXXX 500
E + K + +++ +K +I+E + + E GEEI+ E S+ EK D+
Sbjct: 588 EISNLISKIEDEQAVEIQLQK-KIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELE 646
Query: 501 XXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNM--IN 558
+ + + + +L+ Q A +M +
Sbjct: 647 EISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELG 706
Query: 559 QQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKK-----EKEIKMLNEKE 613
+Q D L + ++ E+ +L+ + +++ E++++ + L K E ++ L KE
Sbjct: 707 EQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKDGGRSLEDQVSELKTKE 766
Query: 614 EEHMNIIN-LLHNKLELRNEA 633
EE +IN L + L+ EA
Sbjct: 767 EEQQRLINDLTAQRARLQTEA 787
Score = 45.6 bits (103), Expect = 6e-04
Identities = 104/592 (17%), Positives = 219/592 (36%), Gaps = 30/592 (5%)
Query: 23 EQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQK 82
E+ + ++ +T+ E + K KK L++ Q ++ L+ K+ +L K
Sbjct: 469 EKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLD---DLQAEEDKVNIL-TK 524
Query: 83 VNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHST-LDNKVTFDVNKLLNIPNSLVD 141
+++ + L E+ L++ + LE L + T D N+ N L +
Sbjct: 525 AKTKLEQQVDDLE-GSLEQEKKLRMDLERAKRKLEGDLKLAQESTMD-NE--NDKQQLDE 580
Query: 142 KCEETLFKRKEIINWFESLMSQEKGISTKT--LTMKIKEFNAENDLLKSS---LDQLRTE 196
K E+ F+ +I+ E + E + K L +I+E E + ++S ++ R++
Sbjct: 581 KLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSD 640
Query: 197 FLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRN 256
+E+ +I + L + T A K+ L E Q H A R
Sbjct: 641 LSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQ-HEA---MVAALRK 696
Query: 257 XXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXX 316
+K +L + + +LK + + A+ +A+ +LE+
Sbjct: 697 KHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKG---NLEKDGGR 753
Query: 317 XXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNK 376
+ ++E +L + L+ A + + +
Sbjct: 754 SLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQ 813
Query: 377 SIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDE 436
I+++KH++ + S + L+E ++ + E + + E+ +
Sbjct: 814 QIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQ 873
Query: 437 KESILETKQCVQ-KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDI 495
+ ET + +ELE K L R E EE+ + K +++ K +L E ++D+
Sbjct: 874 WRTNTETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNE--VEDL 931
Query: 496 XXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGN 555
S+ K YEE + + +Q L V N
Sbjct: 932 MLDVERSNAACAALDKKQRNFDKVL-SEWKQKYEE-TQAELEASQKESRSLSTELFKVKN 989
Query: 556 MINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK 607
+ + D+L E +R+ ++ LQ + +++ + +Q H L K +K+++
Sbjct: 990 VYEESLDQL-ETLRRE---NKNLQQEISDLTEQIAEGGKQIHELEKIKKQVE 1037
Score = 45.2 bits (102), Expect = 8e-04
Identities = 85/464 (18%), Positives = 175/464 (37%), Gaps = 27/464 (5%)
Query: 164 EKGIST-KTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRT 222
EK ++T K K K+ A+++ + L++ LKE ND+ ++ A+ + R
Sbjct: 348 EKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERC 407
Query: 223 KELSCALSDLN------TQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMK 276
++L L T+ AE ++I++ + + + ++
Sbjct: 408 EQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 467
Query: 277 DRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLT 336
E+++K E + L+ + + E +L+ T ED L K
Sbjct: 468 KEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQET-HQQTLDDLQAEEDKVNILTKAK 526
Query: 337 QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIE 396
++ LE +KL+ +S D +++ +++
Sbjct: 527 TKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDNENDKQ-------QLD 579
Query: 397 KKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKT 456
+K E L I+D + ++ + ++K+L ++E +E ++ + + E ++
Sbjct: 580 EKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRS 639
Query: 457 DLEHRKTEIEEYKRLLFEKGEEID---ELKSKLSTE--KAIKDIXXXXXXXXXXXXXXXX 511
DL E+EE L E G EL K E K +D+
Sbjct: 640 DLSR---ELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRK 696
Query: 512 XXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQ 571
Q+ + L+ + ++L+ D+L+ I++ + L + R
Sbjct: 697 KHADSMAELGEQIDNLQRVKQKLEKEKSELKM--ETDDLSSNAEAISKAKGNLEKDGGRS 754
Query: 572 -EEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEI-KMLNEKE 613
E+ +L+TKE E +RL+ +T Q L + E + L+EK+
Sbjct: 755 LEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKD 798
Score = 42.7 bits (96), Expect = 0.004
Identities = 44/241 (18%), Positives = 98/241 (40%), Gaps = 6/241 (2%)
Query: 391 KLIEIEKKYNDSIEEKKTLQ---ENIDDLRTDLLESELRVKDLVRELDEKESILETKQC- 446
+L +++ Y +S+++ +TL+ +N+ +DL E + EL++ + +E ++C
Sbjct: 983 ELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCE 1042
Query: 447 VQKELESTKTDLEHRKTEIEEYKRLLFEKGEEID-ELKSKLSTEKAIKDIXXXXXXXXXX 505
+Q LE + LEH + +I + L + E+D ++ K +K
Sbjct: 1043 IQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQS 1102
Query: 506 XXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLF 565
+ +M+ E+ N +L + N + ++ + + L
Sbjct: 1103 TLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAA-ESLRNYRNTQGILKETQLHLD 1161
Query: 566 ELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHN 625
+ + QE+ E+L E L + E L + E+ K+ ++ + + LLH
Sbjct: 1162 DALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHT 1221
Query: 626 K 626
+
Sbjct: 1222 Q 1222
Score = 35.5 bits (78), Expect = 0.65
Identities = 40/211 (18%), Positives = 87/211 (41%), Gaps = 11/211 (5%)
Query: 285 QLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTT 344
Q + E +L+ AL +A SE + + E+ ++ KL Q +++
Sbjct: 849 QYEEEQEGKAELQRALSKANSE---VAQWRTNTETDAIQRTEELEEAKKKLAQRLQEAEE 905
Query: 345 HLEDI---ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYND 401
H+E + + EK + N + + + L E ++KY +
Sbjct: 906 HVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEE 965
Query: 402 SIEEKKTLQENIDDLRTDLLESELRVKDLVRE-LDEKESILETKQCVQKELESTKTDLEH 460
+ E + Q+ L T+L +VK++ E LD+ E++ + +Q+E+ +
Sbjct: 966 TQAELEASQKESRSLSTELF----KVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAE 1021
Query: 461 RKTEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
+I E +++ + +E E+++ L +A
Sbjct: 1022 GGKQIHELEKIKKQVEQEKCEIQAALEEAEA 1052
>M58018-1|AAA62830.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 47.6 bits (108), Expect = 2e-04
Identities = 51/265 (19%), Positives = 110/265 (41%), Gaps = 13/265 (4%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLV 431
AS + +K + + A+ E+E+K ++EK LQ + + +L ++E R L+
Sbjct: 850 ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLI 909
Query: 432 R-------ELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDEL-K 483
+ ++ E LE ++ + EL + K LE E E KR + + + ++ K
Sbjct: 910 KNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLE---DECSELKRDIDDLELTLAKVEK 966
Query: 484 SKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLRE 543
K +TE +K++ + + E + N +T+ +
Sbjct: 967 EKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAE-EDKVNTLTKAK- 1024
Query: 544 FGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKE 603
++D+ + Q++ +L + + + + L+ + I L + + L KK+
Sbjct: 1025 VKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKD 1084
Query: 604 KEIKMLNEKEEEHMNIINLLHNKLE 628
E+ LN + E+ + + L KL+
Sbjct: 1085 FELNALNARIEDEQALGSQLQKKLK 1109
Score = 46.4 bits (105), Expect = 3e-04
Identities = 90/493 (18%), Positives = 184/493 (37%), Gaps = 25/493 (5%)
Query: 149 KRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCL 208
K ++ ++ E + QEK + K ++ + L + S+ L + K+ D + L
Sbjct: 1026 KLEQQVDDLEGSLEQEKKVRMDLERAK-RKLEGDLKLTQESIMDLEND--KQQLD--ERL 1080
Query: 209 RKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXX 268
+K E AL R ++ S L + E++ +I + + R
Sbjct: 1081 KKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELE-SERTARAKVEKLRSDL 1139
Query: 269 XXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDF 328
+ +RL A +E + EA ++ R + LE +
Sbjct: 1140 SRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRD---LEEATLQHEATAAALRKKH 1196
Query: 329 DQELNKLTQSIKDNTTHLEDIALAREKLQ-----SXXXXXXXXXXXXSASYNKSIKDMKH 383
+ +L + I DN ++ L +EK + A+ K + ++
Sbjct: 1197 ADSVAELGEQI-DNLQRVKQ-KLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLED 1254
Query: 384 EMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVR-ELDEKESILE 442
+MN + +K E ++ ND ++ LQ +L L E E + L R +L + + +
Sbjct: 1255 QMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLED 1314
Query: 443 TKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS--TEKAIKDIXXXXX 500
K+ +++E+++ K L H LL E+ EE E K++L KA ++
Sbjct: 1315 LKRQLEEEVKA-KNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT 1373
Query: 501 XXXXXXXXXXXXXXXXXXXRESQMKSYYE--ELMNLKNQITQLREFGAFDNLNDVGNMIN 558
+++ E E +N K + + + + D+ +
Sbjct: 1374 KYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVE 1433
Query: 559 QQRDKLFELTKRQEEYDEKL---QTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEE 615
+ L K+Q +D+ L + K E + +ES ++ L+ + ++K E+ E
Sbjct: 1434 RSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLE 1493
Query: 616 HMNIINLLHNKLE 628
H+ + L+
Sbjct: 1494 HLETFKRENKNLQ 1506
Score = 45.2 bits (102), Expect = 8e-04
Identities = 49/269 (18%), Positives = 119/269 (44%), Gaps = 4/269 (1%)
Query: 389 IAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQ 448
+ K E EK+ EE L+E ++ E E ++ L++E ++ + ++ +Q
Sbjct: 839 LLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL 898
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA-IKDIXXXXXXXXXXXX 507
+ E L K ++E + + E+ E+ +E+ ++L+ +K ++D
Sbjct: 899 ADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLE 958
Query: 508 XXXXXXXXXXXXRESQMKSYYEELMNLKNQITQL-REFGAFDNLNDVG-NMINQQRDKLF 565
E+++K+ EE+ L I +L +E A + + + + DK+
Sbjct: 959 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVN 1018
Query: 566 ELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHN 625
LTK + + ++++ E +++ + + E K E ++K+ E + N L
Sbjct: 1019 TLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDE 1078
Query: 626 KLELRNEADIDVIITLAKYKKSLTLVLEK 654
+L+ + + +++ + + +++L L+K
Sbjct: 1079 RLK-KKDFELNALNARIEDEQALGSQLQK 1106
Score = 41.1 bits (92), Expect = 0.013
Identities = 109/628 (17%), Positives = 234/628 (37%), Gaps = 42/628 (6%)
Query: 14 DGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTH 73
+G L L+E+E++ S+ +T+ K + +++ E K++LE+ L +L++
Sbjct: 1284 NGELSRQLDEKEALISQ---LTRGKLTYTQQL---EDLKRQLEEEVKAKNALAHALQSAR 1337
Query: 74 RKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLL 133
LL ++ + + + V + ++ Q E A++ + + + + L
Sbjct: 1338 HDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1397
Query: 134 NIPNSLVD----KCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSS 189
V+ KC + + N E LM + + + K+ N D + +
Sbjct: 1398 QEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNF--DKILAE 1455
Query: 190 LDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHH 249
Q E E+ R + E L+ +E L +N ++++I
Sbjct: 1456 WKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQ 1515
Query: 250 RPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWS 309
+ + + + L AE L+ ++++ + Q ++E
Sbjct: 1516 LGSSGKTIHELEKVRKQLEAEKMEL-QSALEEAEASLEHEEGKILRAQLEFNQIKAE--- 1571
Query: 310 LERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXX 369
+ER + + + ++ L S+ T + ++K++
Sbjct: 1572 IERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSH 1631
Query: 370 XSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKD 429
+ ++ K +K +L L + + + +D++ L+ENI + E R
Sbjct: 1632 ANRMAAEAQKQVKSLQSL----LKDTQIQLDDAVRANDDLKENIAIV-------ERRNNL 1680
Query: 430 LVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
L EL+E +++E + +K E + R + L + +++D S+L TE
Sbjct: 1681 LQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTE 1740
Query: 490 KAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEEL-MNLKNQITQLREFGAFD 548
+E ++ E + N++ I L+ D
Sbjct: 1741 VEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQH--RLD 1798
Query: 549 NLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM 608
+ + + +L +L R E + +L E E KR ES+ + K E+ IK
Sbjct: 1799 EAEQIA--LKGGKKQLQKLEARVRELENEL---EAEQKRNAESVKG----MRKSERRIKE 1849
Query: 609 LN-EKEEEHMNIINL--LHNKLELRNEA 633
L + EE+ N++ L L +KL+L+ +A
Sbjct: 1850 LTYQTEEDRKNLLRLQDLVDKLQLKVKA 1877
Score = 39.1 bits (87), Expect = 0.053
Identities = 84/477 (17%), Positives = 183/477 (38%), Gaps = 37/477 (7%)
Query: 22 NEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQ 81
+ Q+ S S ++ KLK ++E + E K+E ++ Q ++ +L L ++ + + L +
Sbjct: 1469 SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEK 1528
Query: 82 KVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVD 141
AE++ + + + + L E K L N++ ++ + L + +
Sbjct: 1529 VRKQLEAEKMELQSALEEAEASL----EHEEGKILRAQLEFNQIKAEIERKLAEKD---E 1581
Query: 142 KCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIK---EFNAENDLLKSSLDQLRTEFL 198
+ E+ +++ ++ + E + L +K K + N E ++ S +++ E
Sbjct: 1582 EMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN-EMEIQLSHANRMAAEAQ 1640
Query: 199 KEINDIIDCLRK---------NANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHH 249
K++ + L+ AN+ + + E L L + E+R + +
Sbjct: 1641 KQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNL--LQAELEELRAVVEQTERS 1698
Query: 250 RPYANRNXXXXXXXXXXXXXXXXSIM--KDRLSRAEHQLKTNVERVVQLEAALEQARSES 307
R A + S++ K ++ QL+T VE VQ E+ ++
Sbjct: 1699 RKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKA 1758
Query: 308 WSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHL---EDIAL--AREKLQSXXXX 362
+ + ++ + Q+IKD L E IAL +++LQ
Sbjct: 1759 ITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEAR 1818
Query: 363 XXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLE 422
A ++ + +K M + ++ E+ + + + LQ+ +D L
Sbjct: 1819 VRELENELEAEQKRNAESVK-GMRKSERRIKELTYQTEEDRKNLLRLQDLVDKL------ 1871
Query: 423 SELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI 479
+L+VK R+ +E E T ++++ + E R E L K +I
Sbjct: 1872 -QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDI 1927
>M57965-1|AAA51837.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 47.6 bits (108), Expect = 2e-04
Identities = 51/265 (19%), Positives = 110/265 (41%), Gaps = 13/265 (4%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLV 431
AS + +K + + A+ E+E+K ++EK LQ + + +L ++E R L+
Sbjct: 850 ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLI 909
Query: 432 R-------ELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDEL-K 483
+ ++ E LE ++ + EL + K LE E E KR + + + ++ K
Sbjct: 910 KNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLE---DECSELKRDIDDLELTLAKVEK 966
Query: 484 SKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLRE 543
K +TE +K++ + + E + N +T+ +
Sbjct: 967 EKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAE-EDKVNTLTKAK- 1024
Query: 544 FGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKE 603
++D+ + Q++ +L + + + + L+ + I L + + L KK+
Sbjct: 1025 VKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKD 1084
Query: 604 KEIKMLNEKEEEHMNIINLLHNKLE 628
E+ LN + E+ + + L KL+
Sbjct: 1085 FELNALNARIEDEQALGSQLQKKLK 1109
Score = 46.4 bits (105), Expect = 3e-04
Identities = 90/493 (18%), Positives = 184/493 (37%), Gaps = 25/493 (5%)
Query: 149 KRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCL 208
K ++ ++ E + QEK + K ++ + L + S+ L + K+ D + L
Sbjct: 1026 KLEQQVDDLEGSLEQEKKVRMDLERAK-RKLEGDLKLTQESIMDLEND--KQQLD--ERL 1080
Query: 209 RKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXX 268
+K E AL R ++ S L + E++ +I + + R
Sbjct: 1081 KKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELE-SERTARAKVEKLRSDL 1139
Query: 269 XXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDF 328
+ +RL A +E + EA ++ R + LE +
Sbjct: 1140 SRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRD---LEEATLQHEATAAALRKKH 1196
Query: 329 DQELNKLTQSIKDNTTHLEDIALAREKLQ-----SXXXXXXXXXXXXSASYNKSIKDMKH 383
+ +L + I DN ++ L +EK + A+ K + ++
Sbjct: 1197 ADSVAELGEQI-DNLQRVKQ-KLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLED 1254
Query: 384 EMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVR-ELDEKESILE 442
+MN + +K E ++ ND ++ LQ +L L E E + L R +L + + +
Sbjct: 1255 QMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLED 1314
Query: 443 TKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS--TEKAIKDIXXXXX 500
K+ +++E+++ K L H LL E+ EE E K++L KA ++
Sbjct: 1315 LKRQLEEEVKA-KNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT 1373
Query: 501 XXXXXXXXXXXXXXXXXXXRESQMKSYYE--ELMNLKNQITQLREFGAFDNLNDVGNMIN 558
+++ E E +N K + + + + D+ +
Sbjct: 1374 KYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVE 1433
Query: 559 QQRDKLFELTKRQEEYDEKL---QTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEE 615
+ L K+Q +D+ L + K E + +ES ++ L+ + ++K E+ E
Sbjct: 1434 RSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLE 1493
Query: 616 HMNIINLLHNKLE 628
H+ + L+
Sbjct: 1494 HLETFKRENKNLQ 1506
Score = 45.2 bits (102), Expect = 8e-04
Identities = 49/269 (18%), Positives = 119/269 (44%), Gaps = 4/269 (1%)
Query: 389 IAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQ 448
+ K E EK+ EE L+E ++ E E ++ L++E ++ + ++ +Q
Sbjct: 839 LLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL 898
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA-IKDIXXXXXXXXXXXX 507
+ E L K ++E + + E+ E+ +E+ ++L+ +K ++D
Sbjct: 899 ADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLE 958
Query: 508 XXXXXXXXXXXXRESQMKSYYEELMNLKNQITQL-REFGAFDNLNDVG-NMINQQRDKLF 565
E+++K+ EE+ L I +L +E A + + + + DK+
Sbjct: 959 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVN 1018
Query: 566 ELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHN 625
LTK + + ++++ E +++ + + E K E ++K+ E + N L
Sbjct: 1019 TLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDE 1078
Query: 626 KLELRNEADIDVIITLAKYKKSLTLVLEK 654
+L+ + + +++ + + +++L L+K
Sbjct: 1079 RLK-KKDFELNALNARIEDEQALGSQLQK 1106
Score = 41.1 bits (92), Expect = 0.013
Identities = 109/628 (17%), Positives = 234/628 (37%), Gaps = 42/628 (6%)
Query: 14 DGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTH 73
+G L L+E+E++ S+ +T+ K + +++ E K++LE+ L +L++
Sbjct: 1284 NGELSRQLDEKEALISQ---LTRGKLTYTQQL---EDLKRQLEEEVKAKNALAHALQSAR 1337
Query: 74 RKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLL 133
LL ++ + + + V + ++ Q E A++ + + + + L
Sbjct: 1338 HDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1397
Query: 134 NIPNSLVD----KCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSS 189
V+ KC + + N E LM + + + K+ N D + +
Sbjct: 1398 QEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNF--DKILAE 1455
Query: 190 LDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHH 249
Q E E+ R + E L+ +E L +N ++++I
Sbjct: 1456 WKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQ 1515
Query: 250 RPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWS 309
+ + + + L AE L+ ++++ + Q ++E
Sbjct: 1516 LGSSGKTIHELEKVRKQLEAEKMEL-QSALEEAEASLEHEEGKILRAQLEFNQIKAE--- 1571
Query: 310 LERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXX 369
+ER + + + ++ L S+ T + ++K++
Sbjct: 1572 IERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSH 1631
Query: 370 XSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKD 429
+ ++ K +K +L L + + + +D++ L+ENI + E R
Sbjct: 1632 ANRMAAEAQKQVKSLQSL----LKDTQIQLDDAVRANDDLKENIAIV-------ERRNNL 1680
Query: 430 LVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
L EL+E +++E + +K E + R + L + +++D S+L TE
Sbjct: 1681 LQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTE 1740
Query: 490 KAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEEL-MNLKNQITQLREFGAFD 548
+E ++ E + N++ I L+ D
Sbjct: 1741 VEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQH--RLD 1798
Query: 549 NLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM 608
+ + + +L +L R E + +L E E KR ES+ + K E+ IK
Sbjct: 1799 EAEQIA--LKGGKKQLQKLEARVRELENEL---EAEQKRNAESVKG----MRKSERRIKE 1849
Query: 609 LN-EKEEEHMNIINL--LHNKLELRNEA 633
L + EE+ N++ L L +KL+L+ +A
Sbjct: 1850 LTYQTEEDRKNLLRLQDLVDKLQLKVKA 1877
Score = 39.1 bits (87), Expect = 0.053
Identities = 84/477 (17%), Positives = 183/477 (38%), Gaps = 37/477 (7%)
Query: 22 NEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQ 81
+ Q+ S S ++ KLK ++E + E K+E ++ Q ++ +L L ++ + + L +
Sbjct: 1469 SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEK 1528
Query: 82 KVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVD 141
AE++ + + + + L E K L N++ ++ + L + +
Sbjct: 1529 VRKQLEAEKMELQSALEEAEASL----EHEEGKILRAQLEFNQIKAEIERKLAEKD---E 1581
Query: 142 KCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIK---EFNAENDLLKSSLDQLRTEFL 198
+ E+ +++ ++ + E + L +K K + N E ++ S +++ E
Sbjct: 1582 EMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN-EMEIQLSHANRMAAEAQ 1640
Query: 199 KEINDIIDCLRK---------NANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHH 249
K++ + L+ AN+ + + E L L + E+R + +
Sbjct: 1641 KQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNL--LQAELEELRAVVEQTERS 1698
Query: 250 RPYANRNXXXXXXXXXXXXXXXXSIM--KDRLSRAEHQLKTNVERVVQLEAALEQARSES 307
R A + S++ K ++ QL+T VE VQ E+ ++
Sbjct: 1699 RKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKA 1758
Query: 308 WSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHL---EDIAL--AREKLQSXXXX 362
+ + ++ + Q+IKD L E IAL +++LQ
Sbjct: 1759 ITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEAR 1818
Query: 363 XXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLE 422
A ++ + +K M + ++ E+ + + + LQ+ +D L
Sbjct: 1819 VRELENELEAEQKRNAESVK-GMRKSERRIKELTYQTEEDRKNLLRLQDLVDKL------ 1871
Query: 423 SELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI 479
+L+VK R+ +E E T ++++ + E R E L K +I
Sbjct: 1872 -QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDI 1927
>EF179180-1|ABN05283.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 47.6 bits (108), Expect = 2e-04
Identities = 51/265 (19%), Positives = 110/265 (41%), Gaps = 13/265 (4%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLV 431
AS + +K + + A+ E+E+K ++EK LQ + + +L ++E R L+
Sbjct: 850 ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLI 909
Query: 432 R-------ELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDEL-K 483
+ ++ E LE ++ + EL + K LE E E KR + + + ++ K
Sbjct: 910 KNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLE---DECSELKRDIDDLELTLAKVEK 966
Query: 484 SKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLRE 543
K +TE +K++ + + E + N +T+ +
Sbjct: 967 EKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAE-EDKVNTLTKAK- 1024
Query: 544 FGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKE 603
++D+ + Q++ +L + + + + L+ + I L + + L KK+
Sbjct: 1025 VKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKD 1084
Query: 604 KEIKMLNEKEEEHMNIINLLHNKLE 628
E+ LN + E+ + + L KL+
Sbjct: 1085 FELNALNARIEDEQALGSQLQKKLK 1109
Score = 47.6 bits (108), Expect = 2e-04
Identities = 91/493 (18%), Positives = 184/493 (37%), Gaps = 25/493 (5%)
Query: 149 KRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCL 208
K ++ ++ E + QEK + K ++ + L + S+ L + K+ D + L
Sbjct: 1026 KLEQQVDDLEGSLEQEKKVRMDLERAK-RKLEGDLKLTQESIMDLEND--KQQLD--ERL 1080
Query: 209 RKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXX 268
+K E AL R ++ S L + E++ +I + A R
Sbjct: 1081 KKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELE-AERTARAKVEKLRSDL 1139
Query: 269 XXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDF 328
+ +RL A +E + EA ++ R + LE +
Sbjct: 1140 SRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRD---LEEATLQHEATAAALRKKH 1196
Query: 329 DQELNKLTQSIKDNTTHLEDIALAREKLQ-----SXXXXXXXXXXXXSASYNKSIKDMKH 383
+ +L + I DN ++ L +EK + A+ K + ++
Sbjct: 1197 ADSVAELGEQI-DNLQRVKQ-KLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLED 1254
Query: 384 EMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVR-ELDEKESILE 442
+MN + +K E ++ ND ++ LQ +L L E E + L R +L + + +
Sbjct: 1255 QMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLED 1314
Query: 443 TKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS--TEKAIKDIXXXXX 500
K+ +++E+++ K L H LL E+ EE E K++L KA ++
Sbjct: 1315 LKRQLEEEVKA-KNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT 1373
Query: 501 XXXXXXXXXXXXXXXXXXXRESQMKSYYE--ELMNLKNQITQLREFGAFDNLNDVGNMIN 558
+++ E E +N K + + + + D+ +
Sbjct: 1374 KYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVE 1433
Query: 559 QQRDKLFELTKRQEEYDEKL---QTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEE 615
+ L K+Q +D+ L + K E + +ES ++ L+ + ++K E+ E
Sbjct: 1434 RSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLE 1493
Query: 616 HMNIINLLHNKLE 628
H+ + L+
Sbjct: 1494 HLETFKRENKNLQ 1506
Score = 45.2 bits (102), Expect = 8e-04
Identities = 49/269 (18%), Positives = 119/269 (44%), Gaps = 4/269 (1%)
Query: 389 IAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQ 448
+ K E EK+ EE L+E ++ E E ++ L++E ++ + ++ +Q
Sbjct: 839 LLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL 898
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA-IKDIXXXXXXXXXXXX 507
+ E L K ++E + + E+ E+ +E+ ++L+ +K ++D
Sbjct: 899 ADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLE 958
Query: 508 XXXXXXXXXXXXRESQMKSYYEELMNLKNQITQL-REFGAFDNLNDVG-NMINQQRDKLF 565
E+++K+ EE+ L I +L +E A + + + + DK+
Sbjct: 959 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVN 1018
Query: 566 ELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHN 625
LTK + + ++++ E +++ + + E K E ++K+ E + N L
Sbjct: 1019 TLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDE 1078
Query: 626 KLELRNEADIDVIITLAKYKKSLTLVLEK 654
+L+ + + +++ + + +++L L+K
Sbjct: 1079 RLK-KKDFELNALNARIEDEQALGSQLQK 1106
Score = 41.1 bits (92), Expect = 0.013
Identities = 109/628 (17%), Positives = 234/628 (37%), Gaps = 42/628 (6%)
Query: 14 DGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTH 73
+G L L+E+E++ S+ +T+ K + +++ E K++LE+ L +L++
Sbjct: 1284 NGELSRQLDEKEALISQ---LTRGKLTYTQQL---EDLKRQLEEEVKAKNALAHALQSAR 1337
Query: 74 RKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLL 133
LL ++ + + + V + ++ Q E A++ + + + + L
Sbjct: 1338 HDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1397
Query: 134 NIPNSLVD----KCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSS 189
V+ KC + + N E LM + + + K+ N D + +
Sbjct: 1398 QEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNF--DKILAE 1455
Query: 190 LDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHH 249
Q E E+ R + E L+ +E L +N ++++I
Sbjct: 1456 WKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQ 1515
Query: 250 RPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWS 309
+ + + + L AE L+ ++++ + Q ++E
Sbjct: 1516 LGSSGKTIHELEKVRKQLEAEKMEL-QSALEEAEASLEHEEGKILRAQLEFNQIKAE--- 1571
Query: 310 LERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXX 369
+ER + + + ++ L S+ T + ++K++
Sbjct: 1572 IERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSH 1631
Query: 370 XSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKD 429
+ ++ K +K +L L + + + +D++ L+ENI + E R
Sbjct: 1632 ANRMAAEAQKQVKSLQSL----LKDTQIQLDDAVRANDDLKENIAIV-------ERRNNL 1680
Query: 430 LVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
L EL+E +++E + +K E + R + L + +++D S+L TE
Sbjct: 1681 LQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTE 1740
Query: 490 KAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEEL-MNLKNQITQLREFGAFD 548
+E ++ E + N++ I L+ D
Sbjct: 1741 VEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQH--RLD 1798
Query: 549 NLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM 608
+ + + +L +L R E + +L E E KR ES+ + K E+ IK
Sbjct: 1799 EAEQIA--LKGGKKQLQKLEARVRELENEL---EAEQKRNAESVKG----MRKSERRIKE 1849
Query: 609 LN-EKEEEHMNIINL--LHNKLELRNEA 633
L + EE+ N++ L L +KL+L+ +A
Sbjct: 1850 LTYQTEEDRKNLLRLQDLVDKLQLKVKA 1877
Score = 39.1 bits (87), Expect = 0.053
Identities = 84/477 (17%), Positives = 183/477 (38%), Gaps = 37/477 (7%)
Query: 22 NEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQ 81
+ Q+ S S ++ KLK ++E + E K+E ++ Q ++ +L L ++ + + L +
Sbjct: 1469 SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEK 1528
Query: 82 KVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVD 141
AE++ + + + + L E K L N++ ++ + L + +
Sbjct: 1529 VRKQLEAEKMELQSALEEAEASL----EHEEGKILRAQLEFNQIKAEIERKLAEKD---E 1581
Query: 142 KCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIK---EFNAENDLLKSSLDQLRTEFL 198
+ E+ +++ ++ + E + L +K K + N E ++ S +++ E
Sbjct: 1582 EMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN-EMEIQLSHANRMAAEAQ 1640
Query: 199 KEINDIIDCLRK---------NANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHH 249
K++ + L+ AN+ + + E L L + E+R + +
Sbjct: 1641 KQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNL--LQAELEELRAVVEQTERS 1698
Query: 250 RPYANRNXXXXXXXXXXXXXXXXSIM--KDRLSRAEHQLKTNVERVVQLEAALEQARSES 307
R A + S++ K ++ QL+T VE VQ E+ ++
Sbjct: 1699 RKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKA 1758
Query: 308 WSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHL---EDIAL--AREKLQSXXXX 362
+ + ++ + Q+IKD L E IAL +++LQ
Sbjct: 1759 ITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEAR 1818
Query: 363 XXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLE 422
A ++ + +K M + ++ E+ + + + LQ+ +D L
Sbjct: 1819 VRELENELEAEQKRNAESVK-GMRKSERRIKELTYQTEEDRKNLLRLQDLVDKL------ 1871
Query: 423 SELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI 479
+L+VK R+ +E E T ++++ + E R E L K +I
Sbjct: 1872 -QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDI 1927
>D86958-1|BAA13194.2| 1593|Homo sapiens KIAA0203 protein.
Length = 1593
Score = 47.6 bits (108), Expect = 2e-04
Identities = 93/455 (20%), Positives = 180/455 (39%), Gaps = 54/455 (11%)
Query: 176 IKEFNAEND----LLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSD 231
+K+ + END LL++ L L LKE+ D + E + R +L +
Sbjct: 964 LKKLHVENDEKLQLLRAELQSLEQSHLKELEDTLQVRHIQEFEKVMTDHRV-----SLEE 1018
Query: 232 LNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVE 291
L +N ++ QI ++ S + D + E +L
Sbjct: 1019 LKKENQQIINQIQE-------SHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEA 1071
Query: 292 RVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIAL 351
+++ LE++R++ +++ E+ E++KL Q I+DN + + + L
Sbjct: 1072 ETDEIKILLEESRAQQKETLKSLLEQET------ENLRTEISKLNQKIQDNNENYQ-VGL 1124
Query: 352 AR-------EKLQSXXXXXXXXXXXXS---ASYNK--SIKDMKHEMNLNIAK-LIEIEKK 398
A EK Q + A NK S+ + E+ N+ + +IE++ K
Sbjct: 1125 AELRTLMTIEKDQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSK 1184
Query: 399 YNDSI-------EEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKEL 451
+ + +EK T QE + LE + R K + + ++E +++ C +K+
Sbjct: 1185 LDSELSALERQKDEKITQQEEKYEAIIQNLEKD-RQKLVSSQEQDREQLIQKLNC-EKD- 1241
Query: 452 ESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXX 511
E+ +T L+ K E E ++ L EK + L+++++ AI
Sbjct: 1242 EAIQTALKEFKLEREVVEKELLEK---VKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQ 1298
Query: 512 XXXXXXXXR-ESQMKSYYEELMNLKNQIT--QLREFGAFDNLNDVG--NMINQQRDKLFE 566
+ E Q K EE+ N++ + Q F + N+IN DKL
Sbjct: 1299 EEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKS 1358
Query: 567 LTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNK 601
++QE + +++ + RL+E + E ++K
Sbjct: 1359 TMQQQERDKDLIESLSEDRARLLEEKKKLEEEVSK 1393
Score = 36.7 bits (81), Expect = 0.28
Identities = 91/461 (19%), Positives = 188/461 (40%), Gaps = 45/461 (9%)
Query: 4 EELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVM 63
E+L++ + + L E E H I + + V + V+ E+ KKE + NQ+
Sbjct: 973 EKLQLLRAELQSLEQSHLKELEDTLQVRH-IQEFEKVMTDHRVSLEELKKENQQIINQIQ 1031
Query: 64 ELYAS-LRNTHRKMKLLGQKVNLPSAE--ELHIMNVAKLSPEQLLQLCAGGEPKALEHST 120
E +A ++ ++++ L KV+ S +L + K + +++ E +A + T
Sbjct: 1032 ESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAETDEIKILL-EESRAQQKET 1090
Query: 121 LDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFN 180
L + + + L + L K ++ + + +LM+ EK + ++ I
Sbjct: 1091 LKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEK---DQCISELISRHE 1147
Query: 181 AENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMR 240
E+++LK+ L+++ T + +I KN E + ++L++K L LS L Q E
Sbjct: 1148 EESNILKAELNKV-TSLHNQAFEI----EKNLKEQI-IELQSK-LDSELSALERQKDEKI 1200
Query: 241 KQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAAL 300
Q + + R + K N E+ ++ AL
Sbjct: 1201 TQ------------QEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTAL 1248
Query: 301 EQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXX 360
++ + LER V + + S + +++ L +A +EKLQ
Sbjct: 1249 KE-----FKLEREVVEKELLEKVKHLENQIAKSPAIDSTRGDSSSL--VAELQEKLQEEK 1301
Query: 361 XXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDL 420
N+ ++ N+ + + E + +N + +K +ENI + +D
Sbjct: 1302 AKFLEQLEEQEKRKNEEMQ------NVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDK 1355
Query: 421 LESEL----RVKDLVRELDE-KESILETKQCVQKELESTKT 456
L+S + R KDL+ L E + +LE K+ +++E+ ++
Sbjct: 1356 LKSTMQQQERDKDLIESLSEDRARLLEEKKKLEEEVSKLRS 1396
Score = 36.3 bits (80), Expect = 0.37
Identities = 23/73 (31%), Positives = 41/73 (56%), Gaps = 4/73 (5%)
Query: 558 NQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMT--EQEHVLNKKEKE--IKMLNEKE 613
N+ KL L K EE + K++ + E+ L E + + E L K EKE I + NEK+
Sbjct: 874 NEYEGKLDGLIKETEENENKIKKLKGELVCLEEVLQNKDNEFALVKHEKEAVICLQNEKD 933
Query: 614 EEHMNIINLLHNK 626
++ + + N++H++
Sbjct: 934 QKLLEMENIMHSQ 946
>D00943-1|BAA00791.1| 1939|Homo sapiens cardiac alpha-myosin heavy
chain protein.
Length = 1939
Score = 47.6 bits (108), Expect = 2e-04
Identities = 51/288 (17%), Positives = 124/288 (43%), Gaps = 6/288 (2%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLV 431
A+ + +K + + A+ E+E+K ++EK LQ + + +L ++E R L+
Sbjct: 852 ATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLI 911
Query: 432 RELDEKES-ILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEK 490
+ + E+ + E + ++ E E +L +K ++E+ L + ++++ +K+ EK
Sbjct: 912 KNKIQLEAKVKEMNERLEDE-EEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 970
Query: 491 -AIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQL--REFGAF 547
A ++ + + ++L ++++ L +
Sbjct: 971 HATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLSKSKVKLE 1030
Query: 548 DNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK 607
++D+ + Q++ +L + + + + L+ + I L + E L KKE +I
Sbjct: 1031 QQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDIN 1090
Query: 608 MLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKM 655
N K E+ + L KL+ N+A I+ + + +++ +EK+
Sbjct: 1091 QQNSKIEDEQVLALQLQKKLK-ENQARIEELEEELEAERTARAKVEKL 1137
Score = 41.1 bits (92), Expect = 0.013
Identities = 66/447 (14%), Positives = 169/447 (37%), Gaps = 17/447 (3%)
Query: 175 KIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNT 234
+IKE +++ + L++ L+E ND+ ++ + + R +L L
Sbjct: 860 RIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEA 919
Query: 235 QNAEMRKQIHSGDHHRPY--ANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVER 292
+ EM +++ + A + + ++ + +H + V+
Sbjct: 920 KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 979
Query: 293 VVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQS---IKDNTTHLEDI 349
+ + A L++ ++ ++ + + + ++N L++S ++ LE
Sbjct: 980 LTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLSKSKVKLEQQVDDLEGS 1039
Query: 350 ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTL 409
+K++ +SI D++++ +++E+K +
Sbjct: 1040 LEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDK-------LQLEEKLKKKEFDINQQ 1092
Query: 410 QENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYK 469
I+D + L+ + ++K+ ++E E LE ++ + ++E ++DL EI E
Sbjct: 1093 NSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISE-- 1150
Query: 470 RLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYE 529
RL G +++ E + + +++ +
Sbjct: 1151 RLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQID 1210
Query: 530 ELMNLKNQITQLR-EFG-AFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKR 587
L +K ++ + + EF D++ I + + L ++++ E+ + + K E +R
Sbjct: 1211 NLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQR 1270
Query: 588 LVESMTEQEHVLNKKEKEI-KMLNEKE 613
+ T Q L + E+ + L EKE
Sbjct: 1271 SLNDFTTQRAKLQTENGELSRQLEEKE 1297
Score = 40.3 bits (90), Expect = 0.023
Identities = 87/488 (17%), Positives = 187/488 (38%), Gaps = 38/488 (7%)
Query: 22 NEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQ 81
+ Q+ S S ++ KLK ++E + E K+E ++ Q ++ +L L + + L +
Sbjct: 1471 SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEK 1530
Query: 82 KVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVD 141
E+L + + + + L E K L N++ ++ + L + +
Sbjct: 1531 VRKQLEVEKLELQSALEEAEASL----EHEEGKILRAQLEFNQIKAEIERKLAEKD---E 1583
Query: 142 KCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIK---EFNAENDLLKSSLDQLRTEFL 198
+ E+ + +++ ++ + E + L +K K + N E ++ S +++ E
Sbjct: 1584 EMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLN-EMEIQLSHANRMAAEAQ 1642
Query: 199 KEINDIIDCLRK---------NANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHH 249
K++ + L+ AN+ + + E L L + E+R + +
Sbjct: 1643 KQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNL--LQAELEELRAVVEQTERS 1700
Query: 250 RPYANRNXXXXXXXXXXXXXXXXSIM--KDRLSRAEHQLKTNVERVVQLEAALEQARSES 307
R A+R S++ K ++ QL++ VE VQ E+ ++
Sbjct: 1701 RKLADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQSEVEEAVQECRNAEEKAKKA 1760
Query: 308 WSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHL---EDIAL--AREKLQSXXXX 362
+ + ++ + Q+IKD L E IAL +++LQ
Sbjct: 1761 ITHAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEAR 1820
Query: 363 XXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLE 422
A ++ + +K M + ++ E+ + + + LQ+ +D L
Sbjct: 1821 VRELEGELEAEQKRNAESVK-GMRKSERRIKELTYQTEEDKKNLLRLQDLVDKL------ 1873
Query: 423 SELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDEL 482
+L+VK R+ +E E T ++++ + E R E L K +I
Sbjct: 1874 -QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIG-A 1931
Query: 483 KSKLSTEK 490
K K+ E+
Sbjct: 1932 KQKMHDEE 1939
Score = 33.1 bits (72), Expect = 3.5
Identities = 63/352 (17%), Positives = 139/352 (39%), Gaps = 22/352 (6%)
Query: 334 KLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLI 393
K S+ + ++++ ++KL+ +++ + IK K + L
Sbjct: 1197 KHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIK-AKANLEKVSRTLE 1255
Query: 394 EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELES 453
+ +Y +EE Q +++D T + + +L R+L+EKE+++ Q + +L
Sbjct: 1256 DQANEYRVKLEEA---QRSLNDFTTQRAKLQTENGELSRQLEEKEALI--SQLTRGKLSY 1310
Query: 454 TKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXX 513
T+ ++E+ KR L E+G+ + L L + + D+
Sbjct: 1311 TQ--------QMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRV 1362
Query: 514 XXXXXXRESQMKSYYE-ELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQE 572
+Q ++ YE + + ++ + ++ A L D + K L K +
Sbjct: 1363 LSKANSEVAQCRTKYETDAIQRTEELEEAKKKLA-QRLQDAEEAVEAVNAKCSSLEKTK- 1420
Query: 573 EYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEI-KMLNEKEEEHMNIINLLHNKLELRN 631
+LQ + ++ VE L+KK++ K+L E ++++ + L + +
Sbjct: 1421 ---HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEAR 1477
Query: 632 EADIDVIITLAKYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRTLRKNMSGL 683
++ Y++SL LE N+ L+ + + Q KN+ L
Sbjct: 1478 SLSTELFKLKNAYEESLE-HLETFKRENKNLQEEISDLTEQLGEGGKNVHEL 1528
>BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6,
cardiac muscle, alpha (cardiomyopathy, hypertrophic 1)
protein.
Length = 1939
Score = 47.6 bits (108), Expect = 2e-04
Identities = 51/288 (17%), Positives = 124/288 (43%), Gaps = 6/288 (2%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLV 431
A+ + +K + + A+ E+E+K ++EK LQ + + +L ++E R L+
Sbjct: 852 ATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLI 911
Query: 432 RELDEKES-ILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEK 490
+ + E+ + E + ++ E E +L +K ++E+ L + ++++ +K+ EK
Sbjct: 912 KNKIQLEAKVKEMNERLEDE-EEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 970
Query: 491 -AIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQL--REFGAF 547
A ++ + + ++L ++++ L +
Sbjct: 971 HATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLE 1030
Query: 548 DNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK 607
++D+ + Q++ +L + + + + L+ + I L + E L KKE +I
Sbjct: 1031 QQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDIN 1090
Query: 608 MLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKM 655
N K E+ + L KL+ N+A I+ + + +++ +EK+
Sbjct: 1091 QQNSKIEDEQVLALQLQKKLK-ENQARIEELEEELEAERTARAKVEKL 1137
Score = 41.1 bits (92), Expect = 0.013
Identities = 66/447 (14%), Positives = 169/447 (37%), Gaps = 17/447 (3%)
Query: 175 KIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNT 234
+IKE +++ + L++ L+E ND+ ++ + + R +L L
Sbjct: 860 RIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEA 919
Query: 235 QNAEMRKQIHSGDHHRPY--ANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVER 292
+ EM +++ + A + + ++ + +H + V+
Sbjct: 920 KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 979
Query: 293 VVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQS---IKDNTTHLEDI 349
+ + A L++ ++ ++ + + + ++N L++S ++ LE
Sbjct: 980 LTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGS 1039
Query: 350 ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTL 409
+K++ +SI D++++ +++E+K +
Sbjct: 1040 LEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDK-------LQLEEKLKKKEFDINQQ 1092
Query: 410 QENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYK 469
I+D + L+ + ++K+ ++E E LE ++ + ++E ++DL EI E
Sbjct: 1093 NSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISE-- 1150
Query: 470 RLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYE 529
RL G +++ E + + +++ +
Sbjct: 1151 RLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQID 1210
Query: 530 ELMNLKNQITQLR-EFG-AFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKR 587
L +K ++ + + EF D++ I + + L ++++ E+ + + K E +R
Sbjct: 1211 NLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQR 1270
Query: 588 LVESMTEQEHVLNKKEKEI-KMLNEKE 613
+ T Q L + E+ + L EKE
Sbjct: 1271 SLNDFTTQRAKLQTENGELARQLEEKE 1297
Score = 37.5 bits (83), Expect = 0.16
Identities = 86/488 (17%), Positives = 186/488 (38%), Gaps = 38/488 (7%)
Query: 22 NEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQ 81
+ Q+ S S ++ KLK ++E + E K+E ++ Q ++ +L L + + L +
Sbjct: 1471 SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEK 1530
Query: 82 KVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVD 141
E+L + + + + L E K L N++ ++ + L + +
Sbjct: 1531 VRKQLEVEKLELQSALEEAEASL----EHEEGKILRAQLEFNQIKAEIERKLAEKD---E 1583
Query: 142 KCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIK---EFNAENDLLKSSLDQLRTEFL 198
+ E+ + +++ ++ + E + L +K K + N E ++ S +++ E
Sbjct: 1584 EMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLN-EMEIQLSHANRMAAEAQ 1642
Query: 199 KEINDIIDCLRK---------NANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHH 249
K++ + L+ AN+ + + E L L + E+R + +
Sbjct: 1643 KQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNL--LQAELEELRAVVEQTERS 1700
Query: 250 RPYANRNXXXXXXXXXXXXXXXXSIM--KDRLSRAEHQLKTNVERVVQLEAALEQARSES 307
R A + S++ K ++ QL++ VE VQ E+ ++
Sbjct: 1701 RKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKA 1760
Query: 308 WSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHL---EDIAL--AREKLQSXXXX 362
+ + ++ + Q+IKD L E IAL +++LQ
Sbjct: 1761 ITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEAR 1820
Query: 363 XXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLE 422
A ++ + +K M + ++ E+ + + + LQ+ +D L
Sbjct: 1821 VRELEGELEAEQKRNAESVK-GMRKSERRIKELTYQTEEDKKNLLRLQDLVDKL------ 1873
Query: 423 SELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDEL 482
+L+VK R+ +E E T ++++ + E R E L K +I
Sbjct: 1874 -QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIG-A 1931
Query: 483 KSKLSTEK 490
K K+ E+
Sbjct: 1932 KQKMHDEE 1939
Score = 33.9 bits (74), Expect = 2.0
Identities = 63/352 (17%), Positives = 139/352 (39%), Gaps = 22/352 (6%)
Query: 334 KLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLI 393
K S+ + ++++ ++KL+ +++ + IK K + L
Sbjct: 1197 KHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIK-AKANLEKVSRTLE 1255
Query: 394 EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELES 453
+ +Y +EE Q +++D T + + +L R+L+EKE+++ Q + +L
Sbjct: 1256 DQANEYRVKLEEA---QRSLNDFTTQRAKLQTENGELARQLEEKEALI--SQLTRGKLSY 1310
Query: 454 TKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXX 513
T+ ++E+ KR L E+G+ + L L + + D+
Sbjct: 1311 TQ--------QMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRV 1362
Query: 514 XXXXXXRESQMKSYYE-ELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQE 572
+Q ++ YE + + ++ + ++ A L D + K L K +
Sbjct: 1363 LSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA-QRLQDAEEAVEAVNAKCSSLEKTK- 1420
Query: 573 EYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEI-KMLNEKEEEHMNIINLLHNKLELRN 631
+LQ + ++ VE L+KK++ K+L E ++++ + L + +
Sbjct: 1421 ---HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEAR 1477
Query: 632 EADIDVIITLAKYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRTLRKNMSGL 683
++ Y++SL LE N+ L+ + + Q KN+ L
Sbjct: 1478 SLSTELFKLKNAYEESLE-HLETFKRENKNLQEEISDLTEQLGEGGKNVHEL 1528
>BC130453-1|AAI30454.1| 1726|Homo sapiens ANKRD26 protein protein.
Length = 1726
Score = 47.6 bits (108), Expect = 2e-04
Identities = 98/537 (18%), Positives = 205/537 (38%), Gaps = 39/537 (7%)
Query: 128 DVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDL-L 186
DV+ L + + CE K + E L + K S L ++ + E L L
Sbjct: 699 DVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMECKD-SVSLLKIQDAALSCERLLEL 757
Query: 187 KSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSG 246
K + +L T +K++ D ++ L++ +ET KE+ S L Q E +++ S
Sbjct: 758 KKNHCELLTVKIKKMEDKVNVLQRELSET-------KEIK---SQLEHQKVEWERELCS- 806
Query: 247 DHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSE 306
R ++++L R E Q + VE QLE +L+ E
Sbjct: 807 -------LRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEME 859
Query: 307 SWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHL---EDIALAREKLQSXXXXX 363
+++ + +E N T HL ++I +A++K+ S
Sbjct: 860 LRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHS 919
Query: 364 XXXXXXXSASYNKSIKDMKHEMNLNIAKLI-EIEKKYNDSIEEKKTLQENIDDLRTDLLE 422
S N +++ + L I + + ++K E+ K ++E +DL+ + +
Sbjct: 920 HEEEKDLSHK-NSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQ 978
Query: 423 SELRVKDLVRELDEKESILETKQC-VQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE 481
+E + + + + + S+L + + +LE+ K E + E+E Y L + D+
Sbjct: 979 NEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQ 1038
Query: 482 LK-SKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQ 540
+ SK E A + Q+ +L +L+ +
Sbjct: 1039 SETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHH 1098
Query: 541 LREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLN 600
R D L + + + + L + + +E ++K Q ++ ++ + + E L+
Sbjct: 1099 TR-----DALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLS 1153
Query: 601 KKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSI 657
+ + E +L ++ ++ HNK + + + I++ + L EK S+
Sbjct: 1154 QLQSENMLLRQQLDD-------AHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSL 1203
Score = 35.5 bits (78), Expect = 0.65
Identities = 104/519 (20%), Positives = 199/519 (38%), Gaps = 49/519 (9%)
Query: 2 KQEELEIQQNQTDGCLYEDLNEQESITSE-SHKITKLKTVWQEKMVTFEKSKKELEDRQN 60
K LEI+ + T L E E + + S ++K + Q+ K K + +Q
Sbjct: 1088 KLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYI-GKQE 1146
Query: 61 QVMELYASLRNTHRKMKL-LGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHS 119
V E + L++ + ++ L N +E ++N+ + +L A E ++L
Sbjct: 1147 SVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLE 1206
Query: 120 TLDNKVTFDVNKLLNIPNSLV-DKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKE 178
+ ++ + N L +K E + R+ ++L Q ++ +T + +
Sbjct: 1207 ERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYR- 1265
Query: 179 FNAENDL--LKSSLDQLRTEFLKEIND----IIDCLRKNANETMALQLRTKELSCALSDL 232
N E++ LK L Q+R + L+E D + C K + L+ +L +
Sbjct: 1266 INLEDETQDLKKKLGQIRNQ-LQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQ 1324
Query: 233 NTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVE- 291
+ E++K + N N ++ L + ++K NVE
Sbjct: 1325 MDKIEELQKNL---------LNANLSEDEKEQLKKLMELKQSLECNL---DQEMKKNVEL 1372
Query: 292 --RVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDI 349
+ + L+ R + E + D ++NKL I D T LE
Sbjct: 1373 EREITGFKNLLKMTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETA 1432
Query: 350 ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNL-----NIAKLIE---IE----K 397
L + K K K++ L N+ IE +E K
Sbjct: 1433 GSKCLHLDTKNQILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVK 1492
Query: 398 KYNDSIEEK--KTLQENIDDLRTDLLESELRVKDLVRELDEK-----ESILETK-QCVQK 449
+Y IEE+ + + E + ++ L+++ ++ + + E +S +E + + ++
Sbjct: 1493 QYKQEIEERARQEIAEKLKEVNL-FLQAQAASQENLEQFRENNFASMKSQMELRIKDLES 1551
Query: 450 ELESTKTDLEH-RKTEIEEYKRLLFEKGEEIDELKSKLS 487
EL KT E KTE+E+YK+L E+ + L SKL+
Sbjct: 1552 ELSKIKTSQEDFNKTELEKYKQLYLEELKVRKSLSSKLT 1590
Score = 33.9 bits (74), Expect = 2.0
Identities = 26/119 (21%), Positives = 58/119 (48%), Gaps = 5/119 (4%)
Query: 567 LTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEI----KMLNEKEEEHMNIINL 622
LT + ++ ++K+ + E+ E ++ EH + E+E+ LN++EE+ N +
Sbjct: 765 LTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRN-ADT 823
Query: 623 LHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRTLRKNMS 681
L+ K+ + + + K+ L L L+ + + R +K +L VV + ++ +S
Sbjct: 824 LYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLS 882
>BC117174-1|AAI17175.1| 1291|Homo sapiens KIF15 protein protein.
Length = 1291
Score = 47.6 bits (108), Expect = 2e-04
Identities = 114/599 (19%), Positives = 236/599 (39%), Gaps = 80/599 (13%)
Query: 56 EDRQNQVMELYASLRNT---HRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGE 112
E + Q++++ L N+ + + K L +K L EL + A L+ E LL+ A
Sbjct: 485 EKLKAQLLQIQTELNNSKQEYEEFKELTRKRQLELESELQSLQKANLNLENLLE--ATKA 542
Query: 113 PKALEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTL 172
K E S L NK+ + K++ P + K + F SL +Q I
Sbjct: 543 CKRQEVSQL-NKIHAETLKIITTPTKAYQLHSRPVPKLSPEMGSFGSLYTQNSSI----- 596
Query: 173 TMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDL 232
+ND+L + E+N+ + E +Q + L L +
Sbjct: 597 --------LDNDILNEPVPP-------EMNE--QAFEAISEELRTVQEQMSALQAKLDEE 639
Query: 233 NTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVER 292
+N ++++ + +HH S +L+ E QL+ +
Sbjct: 640 EHKNLKLQQHVDKLEHHSTQMQELFSSERIDWTKQQEELLS----QLNVLEKQLQETQTK 695
Query: 293 VVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALA 352
L++ + R S ++ + + ++E NKL++ L+++ L
Sbjct: 696 NDFLKSEVHDLRVVLHSADKELSSVKLEYSSFKTNQEKEFNKLSERHMHVQLQLDNLRLE 755
Query: 353 REK--------------LQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKK 398
EK LQ ++ K + +K ++N N+ +L+E EK+
Sbjct: 756 NEKLLESKACLQDSYDNLQEIMKFEIDQLSRNLQNFKKENETLKSDLN-NLMELLEAEKE 814
Query: 399 YNDSI-----EEK----KTLQENIDDLRTDLLESELRVKDLVRELDE-KESILETKQCV- 447
N+ + E+K K + + ++ +R + + + + + ++ + +ES+L T++ +
Sbjct: 815 RNNKLSLQFEEDKENSSKEILKVLEAVRQEKQKETAKCEQQMAKVQKLEESLLATEKVIS 874
Query: 448 --QKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXX 505
+K +S K + +I+E + + EK E ID LK +L KDI
Sbjct: 875 SLEKSRDSDKKVVADLMNQIQELRSSVCEKTETIDTLKQEL------KDINCKYNSALVD 928
Query: 506 XXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLF 565
+K ++++LK + +LR + + + ++L
Sbjct: 929 REESRVL-----------IKKQEVDILDLKETL-RLRILSEDIERDMLCEDLAHATEQLN 976
Query: 566 ELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLH 624
LT+ +++ LQ+ + E+ + + E +H LN+K++E++ +K E + + L H
Sbjct: 977 MLTEASKKHSGLLQSAQEELTKKEALIQELQHKLNQKKEEVE--QKKNEYNFKMRQLEH 1033
Score = 45.2 bits (102), Expect = 8e-04
Identities = 56/294 (19%), Positives = 126/294 (42%), Gaps = 17/294 (5%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLE-SELRVKDLVREL 434
++ + + E+ ++ ++ K ++ + LQ+++D L + EL + +
Sbjct: 613 QAFEAISEELRTVQEQMSALQAKLDEEEHKNLKLQQHVDKLEHHSTQMQELFSSERIDWT 672
Query: 435 DEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA--I 492
++E +L ++K+L+ T+T + K+E+ + + +L +E+ +K + S+ K
Sbjct: 673 KQQEELLSQLNVLEKQLQETQTKNDFLKSEVHDLRVVLHSADKELSSVKLEYSSFKTNQE 732
Query: 493 KDIXXXXXXXXXXXXXXXXXXXXXXXXRESQ--MKSYYEELMN-LKNQITQLREFGAFDN 549
K+ ES+ ++ Y+ L +K +I QL N
Sbjct: 733 KEFNKLSERHMHVQLQLDNLRLENEKLLESKACLQDSYDNLQEIMKFEIDQLSR--NLQN 790
Query: 550 LNDVGNMINQQRDKLFELTKRQEEYDEKL-----QTKEN---EIKRLVESMTEQEHVLNK 601
+ + L EL + ++E + KL + KEN EI +++E++ +++
Sbjct: 791 FKKENETLKSDLNNLMELLEAEKERNNKLSLQFEEDKENSSKEILKVLEAVRQEKQKETA 850
Query: 602 KEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSL-TLVLEK 654
K ++ +K EE + + + LE ++D V+ L + L + V EK
Sbjct: 851 KCEQQMAKVQKLEESLLATEKVISSLEKSRDSDKKVVADLMNQIQELRSSVCEK 904
Score = 39.9 bits (89), Expect = 0.030
Identities = 108/551 (19%), Positives = 215/551 (39%), Gaps = 54/551 (9%)
Query: 142 KCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLK-E 200
K ++ + K + + L S E+ TK + + N L+ + Q + +FLK E
Sbjct: 645 KLQQHVDKLEHHSTQMQELFSSERIDWTKQQEELLSQLNVLEKQLQET--QTKNDFLKSE 702
Query: 201 INDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXX 260
++D+ L E +++L + +E + + N
Sbjct: 703 VHDLRVVLHSADKELSSVKLEYSSFKTNQEKEFNKLSERHMHVQLQLDNLRLENEKLLES 762
Query: 261 XXXXXXXXXXXXSIMK---DRLSR-------AEHQLKTNVERVVQL-EAALEQARSESWS 309
IMK D+LSR LK+++ +++L EA E+ S
Sbjct: 763 KACLQDSYDNLQEIMKFEIDQLSRNLQNFKKENETLKSDLNNLMELLEAEKERNNKLSLQ 822
Query: 310 LERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTH---LEDIALAREKLQSXXXXXXXX 366
E E QE K T + LE+ LA EK+ S
Sbjct: 823 FEEDKENSSKEILKVLEAVRQEKQKETAKCEQQMAKVQKLEESLLATEKVISSLEKSRDS 882
Query: 367 XXXXSASYNKSIKDMKHEM-----NLNIAK--LIEIEKKYNDSI---EEKKTL--QENID 414
A I++++ + ++ K L +I KYN ++ EE + L ++ +D
Sbjct: 883 DKKVVADLMNQIQELRSSVCEKTETIDTLKQELKDINCKYNSALVDREESRVLIKKQEVD 942
Query: 415 --DLRTDL--------LESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTE 464
DL+ L +E ++ +DL ++ + E + L+S + +L ++
Sbjct: 943 ILDLKETLRLRILSEDIERDMLCEDLAHATEQLNMLTEASKKHSGLLQSAQEELTKKEAL 1002
Query: 465 IEEYKRLLFEKGEEIDELKS----KLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXR 520
I+E + L +K EE+++ K+ K+ + + D +
Sbjct: 1003 IQELQHKLNQKKEEVEQKKNEYNFKMRQLEHVMDSAAEDPQSPKTPPHFQTHLAKLLETQ 1062
Query: 521 ESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEK--- 577
E +++ +L++ +T+L E N ++ M Q R+ + L ++ EK
Sbjct: 1063 EQEIEDGRASKTSLEHLVTKLNEDREVKNA-EILRMKEQLRE-MENLRLESQQLIEKNWL 1120
Query: 578 LQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDV 637
LQ + ++IKR E+ ++Q H N++ K + E +E + ++ L+++ AD++
Sbjct: 1121 LQGQLDDIKRQKEN-SDQNHPDNQQLKNEQ--EESIKERLAKSKIVEEMLKMK--ADLEE 1175
Query: 638 IITLAKYKKSL 648
+ + A Y K +
Sbjct: 1176 VQS-ALYNKEM 1185
Score = 31.9 bits (69), Expect = 8.0
Identities = 53/251 (21%), Positives = 107/251 (42%), Gaps = 30/251 (11%)
Query: 3 QEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQV 62
QE++ Q + D +++L Q+ + H T+++ ++ + + + K ++EL + N V
Sbjct: 626 QEQMSALQAKLDEEEHKNLKLQQHVDKLEHHSTQMQELFSSERIDWTKQQEELLSQLN-V 684
Query: 63 MELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLD 122
+E L+ T K L E+H + V S ++ L LE+S+
Sbjct: 685 LE--KQLQETQTKNDFL--------KSEVHDLRVVLHSADKELSSVK------LEYSSFK 728
Query: 123 NKVTFDVNKL--------LNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTM 174
+ NKL L + N ++ E+ L + + + +++L K L+
Sbjct: 729 TNQEKEFNKLSERHMHVQLQLDNLRLEN-EKLLESKACLQDSYDNLQEIMK-FEIDQLSR 786
Query: 175 KIKEFNAENDLLKSSLDQLR--TEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDL 232
++ F EN+ LKS L+ L E KE N+ + + E + ++ K L +
Sbjct: 787 NLQNFKKENETLKSDLNNLMELLEAEKERNNKLSLQFEEDKENSSKEI-LKVLEAVRQEK 845
Query: 233 NTQNAEMRKQI 243
+ A+ +Q+
Sbjct: 846 QKETAKCEQQM 856
>BC112173-1|AAI12174.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 47.6 bits (108), Expect = 2e-04
Identities = 51/265 (19%), Positives = 110/265 (41%), Gaps = 13/265 (4%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLV 431
AS + +K + + A+ E+E+K ++EK LQ + + +L ++E R L+
Sbjct: 850 ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLI 909
Query: 432 R-------ELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDEL-K 483
+ ++ E LE ++ + EL + K LE E E KR + + + ++ K
Sbjct: 910 KNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLE---DECSELKRDIDDLELTLAKVEK 966
Query: 484 SKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLRE 543
K +TE +K++ + + E + N +T+ +
Sbjct: 967 EKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAE-EDKVNTLTKAK- 1024
Query: 544 FGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKE 603
++D+ + Q++ +L + + + + L+ + I L + + L KK+
Sbjct: 1025 VKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKD 1084
Query: 604 KEIKMLNEKEEEHMNIINLLHNKLE 628
E+ LN + E+ + + L KL+
Sbjct: 1085 FELNALNARIEDEQALGSQLQKKLK 1109
Score = 47.6 bits (108), Expect = 2e-04
Identities = 91/493 (18%), Positives = 184/493 (37%), Gaps = 25/493 (5%)
Query: 149 KRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCL 208
K ++ ++ E + QEK + K ++ + L + S+ L + K+ D + L
Sbjct: 1026 KLEQQVDDLEGSLEQEKKVRMDLERAK-RKLEGDLKLTQESIMDLEND--KQQLD--ERL 1080
Query: 209 RKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXX 268
+K E AL R ++ S L + E++ +I + A R
Sbjct: 1081 KKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELE-AERTARAKVEKLRSDL 1139
Query: 269 XXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDF 328
+ +RL A +E + EA ++ R + LE +
Sbjct: 1140 SRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRD---LEEATLQHEATAAALRKKH 1196
Query: 329 DQELNKLTQSIKDNTTHLEDIALAREKLQ-----SXXXXXXXXXXXXSASYNKSIKDMKH 383
+ +L + I DN ++ L +EK + A+ K + ++
Sbjct: 1197 ADSVAELGEQI-DNLQRVKQ-KLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLED 1254
Query: 384 EMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVR-ELDEKESILE 442
+MN + +K E ++ ND ++ LQ +L L E E + L R +L + + +
Sbjct: 1255 QMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLED 1314
Query: 443 TKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS--TEKAIKDIXXXXX 500
K+ +++E+++ K L H LL E+ EE E K++L KA ++
Sbjct: 1315 LKRQLEEEVKA-KNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT 1373
Query: 501 XXXXXXXXXXXXXXXXXXXRESQMKSYYE--ELMNLKNQITQLREFGAFDNLNDVGNMIN 558
+++ E E +N K + + + + D+ +
Sbjct: 1374 KYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVE 1433
Query: 559 QQRDKLFELTKRQEEYDEKL---QTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEE 615
+ L K+Q +D+ L + K E + +ES ++ L+ + ++K E+ E
Sbjct: 1434 RSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLE 1493
Query: 616 HMNIINLLHNKLE 628
H+ + L+
Sbjct: 1494 HLETFKRENKNLQ 1506
Score = 45.2 bits (102), Expect = 8e-04
Identities = 49/269 (18%), Positives = 119/269 (44%), Gaps = 4/269 (1%)
Query: 389 IAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQ 448
+ K E EK+ EE L+E ++ E E ++ L++E ++ + ++ +Q
Sbjct: 839 LLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL 898
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA-IKDIXXXXXXXXXXXX 507
+ E L K ++E + + E+ E+ +E+ ++L+ +K ++D
Sbjct: 899 ADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLE 958
Query: 508 XXXXXXXXXXXXRESQMKSYYEELMNLKNQITQL-REFGAFDNLNDVG-NMINQQRDKLF 565
E+++K+ EE+ L I +L +E A + + + + DK+
Sbjct: 959 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVN 1018
Query: 566 ELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHN 625
LTK + + ++++ E +++ + + E K E ++K+ E + N L
Sbjct: 1019 TLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDE 1078
Query: 626 KLELRNEADIDVIITLAKYKKSLTLVLEK 654
+L+ + + +++ + + +++L L+K
Sbjct: 1079 RLK-KKDFELNALNARIEDEQALGSQLQK 1106
Score = 41.1 bits (92), Expect = 0.013
Identities = 109/628 (17%), Positives = 234/628 (37%), Gaps = 42/628 (6%)
Query: 14 DGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTH 73
+G L L+E+E++ S+ +T+ K + +++ E K++LE+ L +L++
Sbjct: 1284 NGELSRQLDEKEALISQ---LTRGKLTYTQQL---EDLKRQLEEEVKAKNALAHALQSAR 1337
Query: 74 RKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLL 133
LL ++ + + + V + ++ Q E A++ + + + + L
Sbjct: 1338 HDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1397
Query: 134 NIPNSLVD----KCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSS 189
V+ KC + + N E LM + + + K+ N D + +
Sbjct: 1398 QEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNF--DKILAE 1455
Query: 190 LDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHH 249
Q E E+ R + E L+ +E L +N ++++I
Sbjct: 1456 WKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQ 1515
Query: 250 RPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWS 309
+ + + + L AE L+ ++++ + Q ++E
Sbjct: 1516 LGSSGKTIHELEKVRKQLEAEKMEL-QSALEEAEASLEHEEGKILRAQLEFNQIKAE--- 1571
Query: 310 LERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXX 369
+ER + + + ++ L S+ T + ++K++
Sbjct: 1572 IERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSH 1631
Query: 370 XSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKD 429
+ ++ K +K +L L + + + +D++ L+ENI + E R
Sbjct: 1632 ANRMAAEAQKQVKSLQSL----LKDTQIQLDDAVRANDDLKENIAIV-------ERRNNL 1680
Query: 430 LVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
L EL+E +++E + +K E + R + L + +++D S+L TE
Sbjct: 1681 LQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTE 1740
Query: 490 KAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEEL-MNLKNQITQLREFGAFD 548
+E ++ E + N++ I L+ D
Sbjct: 1741 VEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQH--RLD 1798
Query: 549 NLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM 608
+ + + +L +L R E + +L E E KR ES+ + K E+ IK
Sbjct: 1799 EAEQIA--LKGGKKQLQKLEARVRELENEL---EAEQKRNAESVKG----MRKSERRIKE 1849
Query: 609 LN-EKEEEHMNIINL--LHNKLELRNEA 633
L + EE+ N++ L L +KL+L+ +A
Sbjct: 1850 LTYQTEEDRKNLLRLQDLVDKLQLKVKA 1877
Score = 39.1 bits (87), Expect = 0.053
Identities = 84/477 (17%), Positives = 183/477 (38%), Gaps = 37/477 (7%)
Query: 22 NEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQ 81
+ Q+ S S ++ KLK ++E + E K+E ++ Q ++ +L L ++ + + L +
Sbjct: 1469 SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEK 1528
Query: 82 KVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVD 141
AE++ + + + + L E K L N++ ++ + L + +
Sbjct: 1529 VRKQLEAEKMELQSALEEAEASL----EHEEGKILRAQLEFNQIKAEIERKLAEKD---E 1581
Query: 142 KCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIK---EFNAENDLLKSSLDQLRTEFL 198
+ E+ +++ ++ + E + L +K K + N E ++ S +++ E
Sbjct: 1582 EMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN-EMEIQLSHANRMAAEAQ 1640
Query: 199 KEINDIIDCLRK---------NANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHH 249
K++ + L+ AN+ + + E L L + E+R + +
Sbjct: 1641 KQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNL--LQAELEELRAVVEQTERS 1698
Query: 250 RPYANRNXXXXXXXXXXXXXXXXSIM--KDRLSRAEHQLKTNVERVVQLEAALEQARSES 307
R A + S++ K ++ QL+T VE VQ E+ ++
Sbjct: 1699 RKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKA 1758
Query: 308 WSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHL---EDIAL--AREKLQSXXXX 362
+ + ++ + Q+IKD L E IAL +++LQ
Sbjct: 1759 ITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEAR 1818
Query: 363 XXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLE 422
A ++ + +K M + ++ E+ + + + LQ+ +D L
Sbjct: 1819 VRELENELEAEQKRNAESVK-GMRKSERRIKELTYQTEEDRKNLLRLQDLVDKL------ 1871
Query: 423 SELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI 479
+L+VK R+ +E E T ++++ + E R E L K +I
Sbjct: 1872 -QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDI 1927
>BC112171-1|AAI12172.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 47.6 bits (108), Expect = 2e-04
Identities = 51/265 (19%), Positives = 110/265 (41%), Gaps = 13/265 (4%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLV 431
AS + +K + + A+ E+E+K ++EK LQ + + +L ++E R L+
Sbjct: 850 ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLI 909
Query: 432 R-------ELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDEL-K 483
+ ++ E LE ++ + EL + K LE E E KR + + + ++ K
Sbjct: 910 KNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLE---DECSELKRDIDDLELTLAKVEK 966
Query: 484 SKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLRE 543
K +TE +K++ + + E + N +T+ +
Sbjct: 967 EKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAE-EDKVNTLTKAK- 1024
Query: 544 FGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKE 603
++D+ + Q++ +L + + + + L+ + I L + + L KK+
Sbjct: 1025 VKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKD 1084
Query: 604 KEIKMLNEKEEEHMNIINLLHNKLE 628
E+ LN + E+ + + L KL+
Sbjct: 1085 FELNALNARIEDEQALGSQLQKKLK 1109
Score = 47.6 bits (108), Expect = 2e-04
Identities = 91/493 (18%), Positives = 184/493 (37%), Gaps = 25/493 (5%)
Query: 149 KRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCL 208
K ++ ++ E + QEK + K ++ + L + S+ L + K+ D + L
Sbjct: 1026 KLEQQVDDLEGSLEQEKKVRMDLERAK-RKLEGDLKLTQESIMDLEND--KQQLD--ERL 1080
Query: 209 RKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXX 268
+K E AL R ++ S L + E++ +I + A R
Sbjct: 1081 KKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELE-AERTARAKVEKLRSDL 1139
Query: 269 XXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDF 328
+ +RL A +E + EA ++ R + LE +
Sbjct: 1140 SRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRD---LEEATLQHEATAAALRKKH 1196
Query: 329 DQELNKLTQSIKDNTTHLEDIALAREKLQ-----SXXXXXXXXXXXXSASYNKSIKDMKH 383
+ +L + I DN ++ L +EK + A+ K + ++
Sbjct: 1197 ADSVAELGEQI-DNLQRVKQ-KLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLED 1254
Query: 384 EMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVR-ELDEKESILE 442
+MN + +K E ++ ND ++ LQ +L L E E + L R +L + + +
Sbjct: 1255 QMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLED 1314
Query: 443 TKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS--TEKAIKDIXXXXX 500
K+ +++E+++ K L H LL E+ EE E K++L KA ++
Sbjct: 1315 LKRQLEEEVKA-KNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT 1373
Query: 501 XXXXXXXXXXXXXXXXXXXRESQMKSYYE--ELMNLKNQITQLREFGAFDNLNDVGNMIN 558
+++ E E +N K + + + + D+ +
Sbjct: 1374 KYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVE 1433
Query: 559 QQRDKLFELTKRQEEYDEKL---QTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEE 615
+ L K+Q +D+ L + K E + +ES ++ L+ + ++K E+ E
Sbjct: 1434 RSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLE 1493
Query: 616 HMNIINLLHNKLE 628
H+ + L+
Sbjct: 1494 HLETFKRENKNLQ 1506
Score = 45.2 bits (102), Expect = 8e-04
Identities = 49/269 (18%), Positives = 119/269 (44%), Gaps = 4/269 (1%)
Query: 389 IAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQ 448
+ K E EK+ EE L+E ++ E E ++ L++E ++ + ++ +Q
Sbjct: 839 LLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL 898
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA-IKDIXXXXXXXXXXXX 507
+ E L K ++E + + E+ E+ +E+ ++L+ +K ++D
Sbjct: 899 ADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLE 958
Query: 508 XXXXXXXXXXXXRESQMKSYYEELMNLKNQITQL-REFGAFDNLNDVG-NMINQQRDKLF 565
E+++K+ EE+ L I +L +E A + + + + DK+
Sbjct: 959 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVN 1018
Query: 566 ELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHN 625
LTK + + ++++ E +++ + + E K E ++K+ E + N L
Sbjct: 1019 TLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDE 1078
Query: 626 KLELRNEADIDVIITLAKYKKSLTLVLEK 654
+L+ + + +++ + + +++L L+K
Sbjct: 1079 RLK-KKDFELNALNARIEDEQALGSQLQK 1106
Score = 41.1 bits (92), Expect = 0.013
Identities = 109/628 (17%), Positives = 234/628 (37%), Gaps = 42/628 (6%)
Query: 14 DGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTH 73
+G L L+E+E++ S+ +T+ K + +++ E K++LE+ L +L++
Sbjct: 1284 NGELSRQLDEKEALISQ---LTRGKLTYTQQL---EDLKRQLEEEVKAKNALAHALQSAR 1337
Query: 74 RKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLL 133
LL ++ + + + V + ++ Q E A++ + + + + L
Sbjct: 1338 HDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1397
Query: 134 NIPNSLVD----KCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSS 189
V+ KC + + N E LM + + + K+ N D + +
Sbjct: 1398 QEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNF--DKILAE 1455
Query: 190 LDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHH 249
Q E E+ R + E L+ +E L +N ++++I
Sbjct: 1456 WKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQ 1515
Query: 250 RPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWS 309
+ + + + L AE L+ ++++ + Q ++E
Sbjct: 1516 LGSSGKTIHELEKVRKQLEAEKMEL-QSALEEAEASLEHEEGKILRAQLEFNQIKAE--- 1571
Query: 310 LERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXX 369
+ER + + + ++ L S+ T + ++K++
Sbjct: 1572 IERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSH 1631
Query: 370 XSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKD 429
+ ++ K +K +L L + + + +D++ L+ENI + E R
Sbjct: 1632 ANRMAAEAQKQVKSLQSL----LKDTQIQLDDAVRANDDLKENIAIV-------ERRNNL 1680
Query: 430 LVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
L EL+E +++E + +K E + R + L + +++D S+L TE
Sbjct: 1681 LQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTE 1740
Query: 490 KAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEEL-MNLKNQITQLREFGAFD 548
+E ++ E + N++ I L+ D
Sbjct: 1741 VEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQH--RLD 1798
Query: 549 NLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM 608
+ + + +L +L R E + +L E E KR ES+ + K E+ IK
Sbjct: 1799 EAEQIA--LKGGKKQLQKLEARVRELENEL---EAEQKRNAESVKG----MRKSERRIKE 1849
Query: 609 LN-EKEEEHMNIINL--LHNKLELRNEA 633
L + EE+ N++ L L +KL+L+ +A
Sbjct: 1850 LTYQTEEDRKNLLRLQDLVDKLQLKVKA 1877
Score = 39.1 bits (87), Expect = 0.053
Identities = 84/477 (17%), Positives = 183/477 (38%), Gaps = 37/477 (7%)
Query: 22 NEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQ 81
+ Q+ S S ++ KLK ++E + E K+E ++ Q ++ +L L ++ + + L +
Sbjct: 1469 SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEK 1528
Query: 82 KVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVD 141
AE++ + + + + L E K L N++ ++ + L + +
Sbjct: 1529 VRKQLEAEKMELQSALEEAEASL----EHEEGKILRAQLEFNQIKAEIERKLAEKD---E 1581
Query: 142 KCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIK---EFNAENDLLKSSLDQLRTEFL 198
+ E+ +++ ++ + E + L +K K + N E ++ S +++ E
Sbjct: 1582 EMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN-EMEIQLSHANRMAAEAQ 1640
Query: 199 KEINDIIDCLRK---------NANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHH 249
K++ + L+ AN+ + + E L L + E+R + +
Sbjct: 1641 KQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNL--LQAELEELRAVVEQTERS 1698
Query: 250 RPYANRNXXXXXXXXXXXXXXXXSIM--KDRLSRAEHQLKTNVERVVQLEAALEQARSES 307
R A + S++ K ++ QL+T VE VQ E+ ++
Sbjct: 1699 RKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKA 1758
Query: 308 WSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHL---EDIAL--AREKLQSXXXX 362
+ + ++ + Q+IKD L E IAL +++LQ
Sbjct: 1759 ITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEAR 1818
Query: 363 XXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLE 422
A ++ + +K M + ++ E+ + + + LQ+ +D L
Sbjct: 1819 VRELENELEAEQKRNAESVK-GMRKSERRIKELTYQTEEDRKNLLRLQDLVDKL------ 1871
Query: 423 SELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI 479
+L+VK R+ +E E T ++++ + E R E L K +I
Sbjct: 1872 -QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDI 1927
>BC017556-1|AAH17556.1| 1594|Homo sapiens RB1-inducible coiled-coil 1
protein.
Length = 1594
Score = 47.6 bits (108), Expect = 2e-04
Identities = 93/455 (20%), Positives = 180/455 (39%), Gaps = 54/455 (11%)
Query: 176 IKEFNAEND----LLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSD 231
+K+ + END LL++ L L LKE+ D + E + R +L +
Sbjct: 962 LKKLHVENDEKLQLLRAELQSLEQSHLKELEDTLQVRHIQEFEKVMTDHRV-----SLEE 1016
Query: 232 LNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVE 291
L +N ++ QI ++ S + D + E +L
Sbjct: 1017 LKKENQQIINQIQE-------SHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEA 1069
Query: 292 RVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIAL 351
+++ LE++R++ +++ E+ E++KL Q I+DN + + + L
Sbjct: 1070 ETDEIKILLEESRAQQKETLKSLLEQET------ENLRTEISKLNQKIQDNNENYQ-VGL 1122
Query: 352 AR-------EKLQSXXXXXXXXXXXXS---ASYNK--SIKDMKHEMNLNIAK-LIEIEKK 398
A EK Q + A NK S+ + E+ N+ + +IE++ K
Sbjct: 1123 AELRTLMTIEKDQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSK 1182
Query: 399 YNDSI-------EEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKEL 451
+ + +EK T QE + LE + R K + + ++E +++ C +K+
Sbjct: 1183 LDSELSALERQKDEKITQQEEKYEAIIQNLEKD-RQKLVSSQEQDREQLIQKLNC-EKD- 1239
Query: 452 ESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXX 511
E+ +T L+ K E E ++ L EK + L+++++ AI
Sbjct: 1240 EAIQTALKEFKLEREVVEKELLEK---VKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQ 1296
Query: 512 XXXXXXXXR-ESQMKSYYEELMNLKNQIT--QLREFGAFDNLNDVG--NMINQQRDKLFE 566
+ E Q K EE+ N++ + Q F + N+IN DKL
Sbjct: 1297 EEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKS 1356
Query: 567 LTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNK 601
++QE + +++ + RL+E + E ++K
Sbjct: 1357 TMQQQERDKDLIESLSEDRARLLEEKKKLEEEVSK 1391
Score = 36.7 bits (81), Expect = 0.28
Identities = 91/461 (19%), Positives = 188/461 (40%), Gaps = 45/461 (9%)
Query: 4 EELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVM 63
E+L++ + + L E E H I + + V + V+ E+ KKE + NQ+
Sbjct: 971 EKLQLLRAELQSLEQSHLKELEDTLQVRH-IQEFEKVMTDHRVSLEELKKENQQIINQIQ 1029
Query: 64 ELYAS-LRNTHRKMKLLGQKVNLPSAE--ELHIMNVAKLSPEQLLQLCAGGEPKALEHST 120
E +A ++ ++++ L KV+ S +L + K + +++ E +A + T
Sbjct: 1030 ESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAETDEIKILL-EESRAQQKET 1088
Query: 121 LDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFN 180
L + + + L + L K ++ + + +LM+ EK + ++ I
Sbjct: 1089 LKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEK---DQCISELISRHE 1145
Query: 181 AENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMR 240
E+++LK+ L+++ T + +I KN E + ++L++K L LS L Q E
Sbjct: 1146 EESNILKAELNKV-TSLHNQAFEI----EKNLKEQI-IELQSK-LDSELSALERQKDEKI 1198
Query: 241 KQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAAL 300
Q + + R + K N E+ ++ AL
Sbjct: 1199 TQ------------QEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTAL 1246
Query: 301 EQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXX 360
++ + LER V + + S + +++ L +A +EKLQ
Sbjct: 1247 KE-----FKLEREVVEKELLEKVKHLENQIAKSPAIDSTRGDSSSL--VAELQEKLQEEK 1299
Query: 361 XXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDL 420
N+ ++ N+ + + E + +N + +K +ENI + +D
Sbjct: 1300 AKFLEQLEEQEKRKNEEMQ------NVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDK 1353
Query: 421 LESEL----RVKDLVRELDE-KESILETKQCVQKELESTKT 456
L+S + R KDL+ L E + +LE K+ +++E+ ++
Sbjct: 1354 LKSTMQQQERDKDLIESLSEDRARLLEEKKKLEEEVSKLRS 1394
Score = 36.3 bits (80), Expect = 0.37
Identities = 23/73 (31%), Positives = 41/73 (56%), Gaps = 4/73 (5%)
Query: 558 NQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMT--EQEHVLNKKEKE--IKMLNEKE 613
N+ KL L K EE + K++ + E+ L E + + E L K EKE I + NEK+
Sbjct: 872 NEYEGKLDGLIKETEENENKIKKLKGELVCLEEVLQNKDNEFALVKHEKEAVICLQNEKD 931
Query: 614 EEHMNIINLLHNK 626
++ + + N++H++
Sbjct: 932 QKLLEMENIMHSQ 944
>AY518538-1|AAT44534.1| 1179|Homo sapiens rhabdomyosarcoma antigen
MU-RMS-40.7B protein.
Length = 1179
Score = 47.6 bits (108), Expect = 2e-04
Identities = 51/265 (19%), Positives = 110/265 (41%), Gaps = 13/265 (4%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLV 431
AS + +K + + A+ E+E+K ++EK LQ + + +L ++E R L+
Sbjct: 94 ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLI 153
Query: 432 R-------ELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDEL-K 483
+ ++ E LE ++ + EL + K LE E E KR + + + ++ K
Sbjct: 154 KNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLE---DECSELKRDIDDLELTLAKVEK 210
Query: 484 SKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLRE 543
K +TE +K++ + + E + N +T+ +
Sbjct: 211 EKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAE-EDKVNTLTKAK- 268
Query: 544 FGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKE 603
++D+ + Q++ +L + + + + L+ + I L + + L KK+
Sbjct: 269 VKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKD 328
Query: 604 KEIKMLNEKEEEHMNIINLLHNKLE 628
E+ LN + E+ + + L KL+
Sbjct: 329 FELNALNARIEDEQALGSQLQKKLK 353
Score = 47.2 bits (107), Expect = 2e-04
Identities = 91/493 (18%), Positives = 184/493 (37%), Gaps = 25/493 (5%)
Query: 149 KRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCL 208
K ++ ++ E + QEK + K ++ + L + S+ L + K+ D + L
Sbjct: 270 KLEQQVDDLEGSLEQEKKVRMDLERAK-RKLEGDLKLTQESIMDLEND--KQQLD--ERL 324
Query: 209 RKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXX 268
+K E AL R ++ S L + E++ +I + A R
Sbjct: 325 KKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELE-AERTARAKVEKLRSDL 383
Query: 269 XXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDF 328
+ +RL A +E + EA ++ R + LE +
Sbjct: 384 SRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRD---LEEATLQHEATAAALRKKH 440
Query: 329 DQELNKLTQSIKDNTTHLEDIALAREKLQ-----SXXXXXXXXXXXXSASYNKSIKDMKH 383
+ +L + I DN ++ L +EK + A+ K + ++
Sbjct: 441 ADSVAELGEQI-DNLQRVKQ-KLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLED 498
Query: 384 EMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVR-ELDEKESILE 442
+MN + +K E ++ ND ++ LQ +L L E E + L R +L + + +
Sbjct: 499 QMNEHRSKAEETQRSVNDLTSQQAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLED 558
Query: 443 TKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS--TEKAIKDIXXXXX 500
K+ +++E+++ K L H LL E+ EE E K++L KA ++
Sbjct: 559 LKRQLEEEVKA-KNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT 617
Query: 501 XXXXXXXXXXXXXXXXXXXRESQMKSYYE--ELMNLKNQITQLREFGAFDNLNDVGNMIN 558
+++ E E +N K + + + + D+ +
Sbjct: 618 KYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVE 677
Query: 559 QQRDKLFELTKRQEEYDEKL---QTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEE 615
+ L K+Q +D+ L + K E + +ES ++ L+ + ++K E+ E
Sbjct: 678 RSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLE 737
Query: 616 HMNIINLLHNKLE 628
H+ + L+
Sbjct: 738 HLETFKRENKNLQ 750
Score = 45.2 bits (102), Expect = 8e-04
Identities = 49/269 (18%), Positives = 119/269 (44%), Gaps = 4/269 (1%)
Query: 389 IAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQ 448
+ K E EK+ EE L+E ++ E E ++ L++E ++ + ++ +Q
Sbjct: 83 LLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL 142
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA-IKDIXXXXXXXXXXXX 507
+ E L K ++E + + E+ E+ +E+ ++L+ +K ++D
Sbjct: 143 ADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLE 202
Query: 508 XXXXXXXXXXXXRESQMKSYYEELMNLKNQITQL-REFGAFDNLNDVG-NMINQQRDKLF 565
E+++K+ EE+ L I +L +E A + + + + DK+
Sbjct: 203 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVN 262
Query: 566 ELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHN 625
LTK + + ++++ E +++ + + E K E ++K+ E + N L
Sbjct: 263 TLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDE 322
Query: 626 KLELRNEADIDVIITLAKYKKSLTLVLEK 654
+L+ + + +++ + + +++L L+K
Sbjct: 323 RLK-KKDFELNALNARIEDEQALGSQLQK 350
Score = 41.1 bits (92), Expect = 0.013
Identities = 109/628 (17%), Positives = 234/628 (37%), Gaps = 42/628 (6%)
Query: 14 DGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTH 73
+G L L+E+E++ S+ +T+ K + +++ E K++LE+ L +L++
Sbjct: 528 NGELSRQLDEKEALISQ---LTRGKLTYTQQL---EDLKRQLEEEVKAKNALAHALQSAR 581
Query: 74 RKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLL 133
LL ++ + + + V + ++ Q E A++ + + + + L
Sbjct: 582 HDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 641
Query: 134 NIPNSLVD----KCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSS 189
V+ KC + + N E LM + + + K+ N D + +
Sbjct: 642 QEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNF--DKILAE 699
Query: 190 LDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHH 249
Q E E+ R + E L+ +E L +N ++++I
Sbjct: 700 WKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQ 759
Query: 250 RPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWS 309
+ + + + L AE L+ ++++ + Q ++E
Sbjct: 760 LGSSGKTIHELEKVRKQLEAEKMEL-QSALEEAEASLEHEEGKILRAQLEFNQIKAE--- 815
Query: 310 LERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXX 369
+ER + + + ++ L S+ T + ++K++
Sbjct: 816 IERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSH 875
Query: 370 XSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKD 429
+ ++ K +K +L L + + + +D++ L+ENI + E R
Sbjct: 876 ANRMAAEAQKQVKSLQSL----LKDTQIQLDDAVRANDDLKENIAIV-------ERRNNL 924
Query: 430 LVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
L EL+E +++E + +K E + R + L + +++D S+L TE
Sbjct: 925 LQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTE 984
Query: 490 KAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEEL-MNLKNQITQLREFGAFD 548
+E ++ E + N++ I L+ D
Sbjct: 985 VEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQH--RLD 1042
Query: 549 NLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM 608
+ + + +L +L R E + +L E E KR ES+ + K E+ IK
Sbjct: 1043 EAEQIA--LKGGKKQLQKLEARVRELENEL---EAEQKRNAESVKG----MRKSERRIKE 1093
Query: 609 LN-EKEEEHMNIINL--LHNKLELRNEA 633
L + EE+ N++ L L +KL+L+ +A
Sbjct: 1094 LTYQTEEDRKNLLRLQDLVDKLQLKVKA 1121
Score = 39.1 bits (87), Expect = 0.053
Identities = 84/477 (17%), Positives = 183/477 (38%), Gaps = 37/477 (7%)
Query: 22 NEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQ 81
+ Q+ S S ++ KLK ++E + E K+E ++ Q ++ +L L ++ + + L +
Sbjct: 713 SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEK 772
Query: 82 KVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVD 141
AE++ + + + + L E K L N++ ++ + L + +
Sbjct: 773 VRKQLEAEKMELQSALEEAEASL----EHEEGKILRAQLEFNQIKAEIERKLAEKD---E 825
Query: 142 KCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIK---EFNAENDLLKSSLDQLRTEFL 198
+ E+ +++ ++ + E + L +K K + N E ++ S +++ E
Sbjct: 826 EMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN-EMEIQLSHANRMAAEAQ 884
Query: 199 KEINDIIDCLRK---------NANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHH 249
K++ + L+ AN+ + + E L L + E+R + +
Sbjct: 885 KQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNL--LQAELEELRAVVEQTERS 942
Query: 250 RPYANRNXXXXXXXXXXXXXXXXSIM--KDRLSRAEHQLKTNVERVVQLEAALEQARSES 307
R A + S++ K ++ QL+T VE VQ E+ ++
Sbjct: 943 RKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKA 1002
Query: 308 WSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHL---EDIAL--AREKLQSXXXX 362
+ + ++ + Q+IKD L E IAL +++LQ
Sbjct: 1003 ITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEAR 1062
Query: 363 XXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLE 422
A ++ + +K M + ++ E+ + + + LQ+ +D L
Sbjct: 1063 VRELENELEAEQKRNAESVK-GMRKSERRIKELTYQTEEDRKNLLRLQDLVDKL------ 1115
Query: 423 SELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI 479
+L+VK R+ +E E T ++++ + E R E L K +I
Sbjct: 1116 -QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDI 1171
>AL162272-4|CAC19649.1| 1710|Homo sapiens novel protein protein.
Length = 1710
Score = 47.6 bits (108), Expect = 2e-04
Identities = 98/537 (18%), Positives = 205/537 (38%), Gaps = 39/537 (7%)
Query: 128 DVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDL-L 186
DV+ L + + CE K + E L + K S L ++ + E L L
Sbjct: 683 DVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMECKD-SVSLLKIQDAALSCERLLEL 741
Query: 187 KSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSG 246
K + +L T +K++ D ++ L++ +ET KE+ S L Q E +++ S
Sbjct: 742 KKNHCELLTVKIKKMEDKVNVLQRELSET-------KEIK---SQLEHQKVEWERELCS- 790
Query: 247 DHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSE 306
R ++++L R E Q + VE QLE +L+ E
Sbjct: 791 -------LRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEME 843
Query: 307 SWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHL---EDIALAREKLQSXXXXX 363
+++ + +E N T HL ++I +A++K+ S
Sbjct: 844 LRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHS 903
Query: 364 XXXXXXXSASYNKSIKDMKHEMNLNIAKLI-EIEKKYNDSIEEKKTLQENIDDLRTDLLE 422
S N +++ + L I + + ++K E+ K ++E +DL+ + +
Sbjct: 904 HEEEKDLSHK-NSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQ 962
Query: 423 SELRVKDLVRELDEKESILETKQC-VQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE 481
+E + + + + + S+L + + +LE+ K E + E+E Y L + D+
Sbjct: 963 NEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQ 1022
Query: 482 LK-SKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQ 540
+ SK E A + Q+ +L +L+ +
Sbjct: 1023 SETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHH 1082
Query: 541 LREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLN 600
R D L + + + + L + + +E ++K Q ++ ++ + + E L+
Sbjct: 1083 TR-----DALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLS 1137
Query: 601 KKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSI 657
+ + E +L ++ ++ HNK + + + I++ + L EK S+
Sbjct: 1138 QLQSENMLLRQQLDD-------AHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSL 1187
Score = 35.5 bits (78), Expect = 0.65
Identities = 104/519 (20%), Positives = 199/519 (38%), Gaps = 49/519 (9%)
Query: 2 KQEELEIQQNQTDGCLYEDLNEQESITSE-SHKITKLKTVWQEKMVTFEKSKKELEDRQN 60
K LEI+ + T L E E + + S ++K + Q+ K K + +Q
Sbjct: 1072 KLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYI-GKQE 1130
Query: 61 QVMELYASLRNTHRKMKL-LGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHS 119
V E + L++ + ++ L N +E ++N+ + +L A E ++L
Sbjct: 1131 SVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLE 1190
Query: 120 TLDNKVTFDVNKLLNIPNSLV-DKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKE 178
+ ++ + N L +K E + R+ ++L Q ++ +T + +
Sbjct: 1191 ERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYR- 1249
Query: 179 FNAENDL--LKSSLDQLRTEFLKEIND----IIDCLRKNANETMALQLRTKELSCALSDL 232
N E++ LK L Q+R + L+E D + C K + L+ +L +
Sbjct: 1250 INLEDETQDLKKKLGQIRNQ-LQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQ 1308
Query: 233 NTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVE- 291
+ E++K + N N ++ L + ++K NVE
Sbjct: 1309 MDKIEELQKNL---------LNANLSEDEKEQLKKLMELKQSLECNL---DQEMKKNVEL 1356
Query: 292 --RVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDI 349
+ + L+ R + E + D ++NKL I D T LE
Sbjct: 1357 EREITGFKNLLKMTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETA 1416
Query: 350 ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNL-----NIAKLIE---IE----K 397
L + K K K++ L N+ IE +E K
Sbjct: 1417 GSKCLHLDTKNQILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVK 1476
Query: 398 KYNDSIEEK--KTLQENIDDLRTDLLESELRVKDLVRELDEK-----ESILETK-QCVQK 449
+Y IEE+ + + E + ++ L+++ ++ + + E +S +E + + ++
Sbjct: 1477 QYKQEIEERARQEIAEKLKEVNL-FLQAQAASQENLEQFRENNFASMKSQMELRIKDLES 1535
Query: 450 ELESTKTDLEH-RKTEIEEYKRLLFEKGEEIDELKSKLS 487
EL KT E KTE+E+YK+L E+ + L SKL+
Sbjct: 1536 ELSKIKTSQEDFNKTELEKYKQLYLEELKVRKSLSSKLT 1574
Score = 33.9 bits (74), Expect = 2.0
Identities = 26/119 (21%), Positives = 58/119 (48%), Gaps = 5/119 (4%)
Query: 567 LTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEI----KMLNEKEEEHMNIINL 622
LT + ++ ++K+ + E+ E ++ EH + E+E+ LN++EE+ N +
Sbjct: 749 LTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRN-ADT 807
Query: 623 LHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRTLRKNMS 681
L+ K+ + + + K+ L L L+ + + R +K +L VV + ++ +S
Sbjct: 808 LYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLS 866
>AL139421-4|CAI22511.1| 720|Homo sapiens coiled-coil domain
containing 18 protein.
Length = 720
Score = 47.6 bits (108), Expect = 2e-04
Identities = 83/491 (16%), Positives = 186/491 (37%), Gaps = 35/491 (7%)
Query: 177 KEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQN 236
K++ E L + +++LRT+ ++ + D A+ T QL +EL S+ +
Sbjct: 231 KQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLE 290
Query: 237 AEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKD-RLSRAEHQLKTNVERVVQ 295
+EM K+ +M + +L + + Q K + +
Sbjct: 291 SEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMLEAQLEKKDQQFKEQEKTMSM 350
Query: 296 LEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREK 355
L+ + + SL+R + D+ L L + + T + + A E
Sbjct: 351 LQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEI 410
Query: 356 LQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDD 415
+ + K +K E+ + K ++I+ N S++E T ++N+
Sbjct: 411 CKEELVLHLNQLEGNKEKFEKQLKKKSEEVYC-LQKELKIK---NHSLQE--TSEQNVI- 463
Query: 416 LRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIE-EYKRLLFE 474
L L +++ +L+ + ELE T+T LE + +++E E ++
Sbjct: 464 --------------LQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRES 509
Query: 475 KGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNL 534
E++ +++ K + D+ + +M Y EEL +
Sbjct: 510 SAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQV----------KIEMDQYKEELSKM 559
Query: 535 KNQITQLREFGAFD--NLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESM 592
+ +I L+ G +L+ + +++Q + +L + T +E ++ + E E+ ++
Sbjct: 560 EKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKR 619
Query: 593 TEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVL 652
E L E+K + +E +++ LE + D+ L + K +
Sbjct: 620 EVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKK 679
Query: 653 EKMSISNRVLK 663
+++ ++ LK
Sbjct: 680 QELLEMDQALK 690
Score = 35.9 bits (79), Expect = 0.49
Identities = 31/114 (27%), Positives = 52/114 (45%), Gaps = 4/114 (3%)
Query: 382 KHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESIL 441
K E+ + E+EK + + E + + L T+L + +K +R+L E +L
Sbjct: 588 KTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVL 647
Query: 442 ETKQCVQKELESTKTDL--EHR--KTEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
+ Q +E +T DL E R K EIE+ K+ L E + + E +L A
Sbjct: 648 QKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAA 701
>AK128577-1|BAC87508.1| 1080|Homo sapiens protein ( Homo sapiens
cDNA FLJ46736 fis, clone TRACH3020769, weakly similar
to Myosin heavy chain, nonmuscle type B. ).
Length = 1080
Score = 47.6 bits (108), Expect = 2e-04
Identities = 98/537 (18%), Positives = 205/537 (38%), Gaps = 39/537 (7%)
Query: 128 DVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDL-L 186
DV+ L + + CE K + E L + K S L ++ + E L L
Sbjct: 240 DVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMECKD-SVSLLKIQDAALSCERLLEL 298
Query: 187 KSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSG 246
K + +L T +K++ D ++ L++ +ET KE+ S L Q E +++ S
Sbjct: 299 KKNHCELLTVKIKKMEDKVNVLQRELSET-------KEIK---SQLEHQKVEWERELCS- 347
Query: 247 DHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSE 306
R ++++L R E Q + VE QLE +L+ E
Sbjct: 348 -------LRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEME 400
Query: 307 SWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHL---EDIALAREKLQSXXXXX 363
+++ + +E N T HL ++I +A++K+ S
Sbjct: 401 LRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHS 460
Query: 364 XXXXXXXSASYNKSIKDMKHEMNLNIAKLI-EIEKKYNDSIEEKKTLQENIDDLRTDLLE 422
S N +++ + L I + + ++K E+ K ++E +DL+ + +
Sbjct: 461 HEEEKDLSHK-NSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQ 519
Query: 423 SELRVKDLVRELDEKESILETKQC-VQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE 481
+E + + + + + S+L + + +LE+ K E + E+E Y L + D+
Sbjct: 520 NEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQ 579
Query: 482 LK-SKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQ 540
+ SK E A + Q+ +L +L+ +
Sbjct: 580 SETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHH 639
Query: 541 LREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLN 600
R D L + + + + L + + +E ++K Q ++ ++ + + E L+
Sbjct: 640 TR-----DALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLS 694
Query: 601 KKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSI 657
+ + E +L ++ ++ HNK + + + I++ + L EK S+
Sbjct: 695 QLQSENMLLRQQLDD-------AHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSL 744
Score = 33.9 bits (74), Expect = 2.0
Identities = 26/119 (21%), Positives = 58/119 (48%), Gaps = 5/119 (4%)
Query: 567 LTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEI----KMLNEKEEEHMNIINL 622
LT + ++ ++K+ + E+ E ++ EH + E+E+ LN++EE+ N +
Sbjct: 306 LTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRN-ADT 364
Query: 623 LHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRTLRKNMS 681
L+ K+ + + + K+ L L L+ + + R +K +L VV + ++ +S
Sbjct: 365 LYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLS 423
>AK093463-1|BAC04173.1| 650|Homo sapiens protein ( Homo sapiens
cDNA FLJ36144 fis, clone TESTI2025022, weakly similar to
TRICHOHYALIN. ).
Length = 650
Score = 47.6 bits (108), Expect = 2e-04
Identities = 60/303 (19%), Positives = 129/303 (42%), Gaps = 18/303 (5%)
Query: 326 EDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEM 385
E+ +E + L+ + NT E++ +LQ + ++K++K +
Sbjct: 200 EELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESE----KSEIQLNVKELKRK- 254
Query: 386 NLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESE---LRVKDLVRELDEKESILE 442
L AK + + + N EE +E + + + + E R ++ +RE + K E
Sbjct: 255 -LERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQE 313
Query: 443 TKQCVQ-KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKL-STEKAIKDIXXXXX 500
K Q K L + +L ++ E+ E K+L E+ E++ E + K+ E+ +++
Sbjct: 314 EKMWRQEKRLREQEKELREQEKELREQKKLR-EQEEQMQEQEEKMWEQEEKMREQEEKMW 372
Query: 501 XXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLRE----FGAFDNLNDVGNM 556
Q + +E+ L+ + ++RE + + + + M
Sbjct: 373 RQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKM 432
Query: 557 INQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEH 616
Q++ + K QEE E+++ +E +++ E+M EQE + K+E+ + EKE +
Sbjct: 433 QEQEKKTRDQEEKMQEE--ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQ 490
Query: 617 MNI 619
+
Sbjct: 491 QRL 493
Score = 41.9 bits (94), Expect = 0.007
Identities = 53/227 (23%), Positives = 97/227 (42%), Gaps = 17/227 (7%)
Query: 397 KKYNDSIEE--KKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQC-VQKELES 453
KK + IEE K+ +++ R + EL+ K+ EL EK + E+++ +Q ++
Sbjct: 193 KKADRYIEELTKERDALSLELYRNTITNEELKKKNA--ELQEKLPLAESEKSEIQLNVKE 250
Query: 454 TKTDLEHRKTEIEEYKR--LLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXX 511
K LE K + + + L E + +EL+ + EK I+
Sbjct: 251 LKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQ---EKKIRKQEEKMWRQEERLREQEG 307
Query: 512 XXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQ 571
Q K E+ L+ Q +LRE L + + +Q +K++E ++
Sbjct: 308 KMREQEEKMWRQEKRLREQEKELREQEKELREQ---KKLREQEEQMQEQEEKMWEQEEKM 364
Query: 572 EEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEI----KMLNEKEE 614
E +EK+ +E + + M EQE + +E+ + + L EKEE
Sbjct: 365 REQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEE 411
Score = 33.1 bits (72), Expect = 3.5
Identities = 50/247 (20%), Positives = 107/247 (43%), Gaps = 22/247 (8%)
Query: 378 IKDMKHEMNLNIAKLIEIEKKYNDS---IEEKKTLQENIDDLRTD---LLESELRVKDLV 431
+++ + +M +L E EK+ + + E+K L+E + ++ + E E ++++
Sbjct: 309 MREQEEKMWRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQE 368
Query: 432 RELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
++ +E L ++ +E E D E R E +E R E+ E +++ ++ EK
Sbjct: 369 EKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQV--EKM 426
Query: 492 IKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLN 551
++ RE +M+ EE M + + Q +E ++
Sbjct: 427 REEKKMQEQEKKTRDQEEKMQEEERIREREKKMREE-EETMREQEEKMQKQEENMWEQEE 485
Query: 552 DVGNM--INQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEK---EI 606
+ +Q++KL+E EK+Q +E +I E + +QE + +++K E
Sbjct: 486 KEWQQQRLPEQKEKLWE--------QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWQEE 537
Query: 607 KMLNEKE 613
KM ++E
Sbjct: 538 KMWGQEE 544
>AK056673-1|BAB71249.1| 883|Homo sapiens protein ( Homo sapiens
cDNA FLJ32111 fis, clone OCBBF2001528, weakly similar to
MYOSIN HEAVY CHAIN, SMOOTH MUSCLE ISOFORM. ).
Length = 883
Score = 47.6 bits (108), Expect = 2e-04
Identities = 59/249 (23%), Positives = 107/249 (42%), Gaps = 23/249 (9%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD 435
K+ +++K E A L E+ ++N+ +EE TLQ+ +++ E ELR + L+
Sbjct: 635 KNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEE-----SEGELR-----KNLE 684
Query: 436 EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLL-FEKGEEIDELKSKLSTEKAIKD 494
E + ++ Q E+ + L E++ KR EKG I+EL L ++ ++D
Sbjct: 685 ELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEEL---LQAKQDLQD 741
Query: 495 IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQ----ITQLREF--GAFD 548
+ + ++ S+ +E+ LK Q + LRE A
Sbjct: 742 LLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATK 801
Query: 549 NLNDVGNMIN--QQRDKLFEL-TKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKE 605
N+ + + N +Q E+ K +E +E LQ + E++R V + Q L E +
Sbjct: 802 NVEVLASRSNTSEQDQAGTEMRVKLLQEENENLQGRSEELERRVAQLQRQIEDLKGDEAK 861
Query: 606 IKMLNEKEE 614
K +K E
Sbjct: 862 AKETLKKFE 870
Score = 46.4 bits (105), Expect = 3e-04
Identities = 41/218 (18%), Positives = 93/218 (42%), Gaps = 7/218 (3%)
Query: 273 SIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQEL 332
S ++ RL +E +L+ N+E + Q++ EQ ++E L+ + D+E
Sbjct: 666 STLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREK 725
Query: 333 NKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMN----LN 388
L + + L+D+ +A+E+ + + + + EM+
Sbjct: 726 GALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQY 785
Query: 389 IAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQ 448
A+L + + ++ + + L + D +E+RVK L++E E E++ + ++
Sbjct: 786 DAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVK-LLQE--ENENLQGRSEELE 842
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKL 486
+ + + +E K + + K L + EI +L+ L
Sbjct: 843 RRVAQLQRQIEDLKGDEAKAKETLKKFEGEIRQLEEAL 880
Score = 36.7 bits (81), Expect = 0.28
Identities = 27/123 (21%), Positives = 65/123 (52%), Gaps = 11/123 (8%)
Query: 521 ESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYD----- 575
E +++ EEL +K + Q + + D+ + +++ D+L + KR E+ +
Sbjct: 676 EGELRKNLEELFQVKMEREQHQT-----EIRDLQDQLSEMHDEL-DSAKRSEDREKGALI 729
Query: 576 EKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADI 635
E+L + +++ L+ + EQE +L K+E+E+ L +E ++ + +KL+ + +A++
Sbjct: 730 EELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAEL 789
Query: 636 DVI 638
+
Sbjct: 790 QAL 792
>AJ238393-1|CAC20413.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 47.6 bits (108), Expect = 2e-04
Identities = 51/265 (19%), Positives = 110/265 (41%), Gaps = 13/265 (4%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLV 431
AS + +K + + A+ E+E+K ++EK LQ + + +L ++E R L+
Sbjct: 850 ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLI 909
Query: 432 R-------ELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDEL-K 483
+ ++ E LE ++ + EL + K LE E E KR + + + ++ K
Sbjct: 910 KNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLE---DECSELKRDIDDLELTLAKVEK 966
Query: 484 SKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLRE 543
K +TE +K++ + + E + N +T+ +
Sbjct: 967 EKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAE-EDKVNTLTKAK- 1024
Query: 544 FGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKE 603
++D+ + Q++ +L + + + + L+ + I L + + L KK+
Sbjct: 1025 VKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKD 1084
Query: 604 KEIKMLNEKEEEHMNIINLLHNKLE 628
E+ LN + E+ + + L KL+
Sbjct: 1085 FELNALNARIEDEQALGSQLQKKLK 1109
Score = 47.2 bits (107), Expect = 2e-04
Identities = 91/493 (18%), Positives = 184/493 (37%), Gaps = 25/493 (5%)
Query: 149 KRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCL 208
K ++ ++ E + QEK + K ++ + L + S+ L + K+ D + L
Sbjct: 1026 KLEQQVDDLEGSLEQEKKVRMDLERAK-RKLEGDLKLTQESIMDLEND--KQQLD--ERL 1080
Query: 209 RKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXX 268
+K E AL R ++ S L + E++ +I + A R
Sbjct: 1081 KKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELE-AERTARAKVEKLRSDL 1139
Query: 269 XXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDF 328
+ +RL A +E + EA ++ R + LE +
Sbjct: 1140 SRELEEISERLEEAGGATSCQIEMNKKREAEFQKMRRD---LEEATLQHEATAAALRKKH 1196
Query: 329 DQELNKLTQSIKDNTTHLEDIALAREKLQ-----SXXXXXXXXXXXXSASYNKSIKDMKH 383
+ +L + I DN ++ L +EK + A+ K + ++
Sbjct: 1197 ADSVAELGEQI-DNLQRVKQ-KLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLED 1254
Query: 384 EMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVR-ELDEKESILE 442
+MN + +K E ++ ND ++ LQ +L L E E + L R +L + + +
Sbjct: 1255 QMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLED 1314
Query: 443 TKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS--TEKAIKDIXXXXX 500
K+ +++E+++ K L H LL E+ EE E K++L KA ++
Sbjct: 1315 LKRQLEEEVKA-KNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT 1373
Query: 501 XXXXXXXXXXXXXXXXXXXRESQMKSYYE--ELMNLKNQITQLREFGAFDNLNDVGNMIN 558
+++ E E +N K + + + + D+ +
Sbjct: 1374 KYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVE 1433
Query: 559 QQRDKLFELTKRQEEYDEKL---QTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEE 615
+ L K+Q +D+ L + K E + +ES ++ L+ + ++K E+ E
Sbjct: 1434 RSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLE 1493
Query: 616 HMNIINLLHNKLE 628
H+ + L+
Sbjct: 1494 HLETFKRENKNLQ 1506
Score = 45.2 bits (102), Expect = 8e-04
Identities = 49/269 (18%), Positives = 119/269 (44%), Gaps = 4/269 (1%)
Query: 389 IAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQ 448
+ K E EK+ EE L+E ++ E E ++ L++E ++ + ++ +Q
Sbjct: 839 LLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL 898
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA-IKDIXXXXXXXXXXXX 507
+ E L K ++E + + E+ E+ +E+ ++L+ +K ++D
Sbjct: 899 ADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLE 958
Query: 508 XXXXXXXXXXXXRESQMKSYYEELMNLKNQITQL-REFGAFDNLNDVG-NMINQQRDKLF 565
E+++K+ EE+ L I +L +E A + + + + DK+
Sbjct: 959 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVN 1018
Query: 566 ELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHN 625
LTK + + ++++ E +++ + + E K E ++K+ E + N L
Sbjct: 1019 TLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDE 1078
Query: 626 KLELRNEADIDVIITLAKYKKSLTLVLEK 654
+L+ + + +++ + + +++L L+K
Sbjct: 1079 RLK-KKDFELNALNARIEDEQALGSQLQK 1106
Score = 41.1 bits (92), Expect = 0.013
Identities = 109/628 (17%), Positives = 234/628 (37%), Gaps = 42/628 (6%)
Query: 14 DGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTH 73
+G L L+E+E++ S+ +T+ K + +++ E K++LE+ L +L++
Sbjct: 1284 NGELSRQLDEKEALISQ---LTRGKLTYTQQL---EDLKRQLEEEVKAKNALAHALQSAR 1337
Query: 74 RKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLL 133
LL ++ + + + V + ++ Q E A++ + + + + L
Sbjct: 1338 HDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1397
Query: 134 NIPNSLVD----KCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSS 189
V+ KC + + N E LM + + + K+ N D + +
Sbjct: 1398 QEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNF--DKILAE 1455
Query: 190 LDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHH 249
Q E E+ R + E L+ +E L +N ++++I
Sbjct: 1456 WKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQ 1515
Query: 250 RPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWS 309
+ + + + L AE L+ ++++ + Q ++E
Sbjct: 1516 LGSSGKTIHELEKVRKQLEAEKMEL-QSALEEAEASLEHEEGKILRAQLEFNQIKAE--- 1571
Query: 310 LERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXX 369
+ER + + + ++ L S+ T + ++K++
Sbjct: 1572 IERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSH 1631
Query: 370 XSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKD 429
+ ++ K +K +L L + + + +D++ L+ENI + E R
Sbjct: 1632 ANRMAAEAQKQVKSLQSL----LKDTQIQLDDAVRANDDLKENIAIV-------ERRNNL 1680
Query: 430 LVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
L EL+E +++E + +K E + R + L + +++D S+L TE
Sbjct: 1681 LQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTE 1740
Query: 490 KAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEEL-MNLKNQITQLREFGAFD 548
+E ++ E + N++ I L+ D
Sbjct: 1741 VEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQH--RLD 1798
Query: 549 NLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM 608
+ + + +L +L R E + +L E E KR ES+ + K E+ IK
Sbjct: 1799 EAEQIA--LKGGKKQLQKLEARVRELENEL---EAEQKRNAESVKG----MRKSERRIKE 1849
Query: 609 LN-EKEEEHMNIINL--LHNKLELRNEA 633
L + EE+ N++ L L +KL+L+ +A
Sbjct: 1850 LTYQTEEDRKNLLRLQDLVDKLQLKVKA 1877
Score = 39.1 bits (87), Expect = 0.053
Identities = 84/477 (17%), Positives = 183/477 (38%), Gaps = 37/477 (7%)
Query: 22 NEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQ 81
+ Q+ S S ++ KLK ++E + E K+E ++ Q ++ +L L ++ + + L +
Sbjct: 1469 SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEK 1528
Query: 82 KVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVD 141
AE++ + + + + L E K L N++ ++ + L + +
Sbjct: 1529 VRKQLEAEKMELQSALEEAEASL----EHEEGKILRAQLEFNQIKAEIERKLAEKD---E 1581
Query: 142 KCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIK---EFNAENDLLKSSLDQLRTEFL 198
+ E+ +++ ++ + E + L +K K + N E ++ S +++ E
Sbjct: 1582 EMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN-EMEIQLSHANRMAAEAQ 1640
Query: 199 KEINDIIDCLRK---------NANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHH 249
K++ + L+ AN+ + + E L L + E+R + +
Sbjct: 1641 KQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNL--LQAELEELRAVVEQTERS 1698
Query: 250 RPYANRNXXXXXXXXXXXXXXXXSIM--KDRLSRAEHQLKTNVERVVQLEAALEQARSES 307
R A + S++ K ++ QL+T VE VQ E+ ++
Sbjct: 1699 RKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKA 1758
Query: 308 WSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHL---EDIAL--AREKLQSXXXX 362
+ + ++ + Q+IKD L E IAL +++LQ
Sbjct: 1759 ITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEAR 1818
Query: 363 XXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLE 422
A ++ + +K M + ++ E+ + + + LQ+ +D L
Sbjct: 1819 VRELENELEAEQKRNAESVK-GMRKSERRIKELTYQTEEDRKNLLRLQDLVDKL------ 1871
Query: 423 SELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI 479
+L+VK R+ +E E T ++++ + E R E L K +I
Sbjct: 1872 -QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDI 1927
>AF111783-1|AAD29949.1| 1939|Homo sapiens myosin heavy chain IIb
protein.
Length = 1939
Score = 47.6 bits (108), Expect = 2e-04
Identities = 44/226 (19%), Positives = 96/226 (42%), Gaps = 11/226 (4%)
Query: 394 EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELES 453
++ +K E LQ I+D + ++ + ++K+L ++E E +E ++ + + E
Sbjct: 1079 QLNEKLKKKEFEMSNLQGKIEDEQALAMQLQKKIKELQARIEELEEEIEAERASRAKAEK 1138
Query: 454 TKTDLEHRKTEIEEYKRLLFEKGEEID---ELKSKLSTE--KAIKDIXXXXXXXXXXXXX 508
++DL E+EE L E G EL K E K +D+
Sbjct: 1139 QRSDLSR---ELEEISERLEEAGGATSAQIELNKKREAEFQKMRRDLEESTLQHEATAAA 1195
Query: 509 XXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELT 568
Q+ S L+ + ++L+ ++L +++ + ++
Sbjct: 1196 LRKKHADSVAELGKQIDSLQRVKQKLEKEKSELKM--EINDLASNMETVSKAKANFEKMC 1253
Query: 569 KRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEI-KMLNEKE 613
+ E+ +++TKE E +RL+ ++ Q+ L+ + E + L+EK+
Sbjct: 1254 RTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKD 1299
Score = 45.6 bits (103), Expect = 6e-04
Identities = 78/391 (19%), Positives = 152/391 (38%), Gaps = 36/391 (9%)
Query: 277 DRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLT 336
D L+ AE + ++ +QLEA +++ +E E + ED EL K
Sbjct: 900 DALADAEERCDQLIKTKIQLEAKIKEV-TERAEDEEEINAELTAKKRKLEDECSELKKDI 958
Query: 337 QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIE 396
++ +E A E A K K ++ + L E
Sbjct: 959 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEE 1018
Query: 397 KKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVR-----ELDEK---ESILET---KQ 445
K N + K L++ +DDL L + + DL R E D K ES ++T KQ
Sbjct: 1019 DKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQ 1078
Query: 446 CVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS---------------TEK 490
+ ++L+ + ++ + + +IE+ + L + ++I EL++++ EK
Sbjct: 1079 QLNEKLKKKEFEMSNLQGKIEDEQALAMQLQKKIKELQARIEELEEEIEAERASRAKAEK 1138
Query: 491 AIKDIXXXXXXXXXXXXXXXXXXXXXXXX---RESQMKSYYEEL--MNLKNQITQ--LRE 543
D+ RE++ + +L L+++ T LR+
Sbjct: 1139 QRSDLSRELEEISERLEEAGGATSAQIELNKKREAEFQKMRRDLEESTLQHEATAAALRK 1198
Query: 544 FGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKE 603
A D++ ++G I+ + +L K + E ++ + ++ + ++ E + E
Sbjct: 1199 KHA-DSVAELGKQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLE 1257
Query: 604 KEIKMLNEKEEEHMNIIN-LLHNKLELRNEA 633
++ + KEEE +IN L K L E+
Sbjct: 1258 DQLSEIKTKEEEQQRLINELSAQKARLHTES 1288
Score = 43.2 bits (97), Expect = 0.003
Identities = 103/588 (17%), Positives = 213/588 (36%), Gaps = 36/588 (6%)
Query: 42 QEKMVTFEKSKKELEDRQNQVMELYASLRNTHR-KMKLLGQKVNLPSAEELHIMNVAKLS 100
+++ F+K +++LE+ Q A+LR H + LG++++ + V +
Sbjct: 1169 KKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGKQID-------SLQRVKQKL 1221
Query: 101 PEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESL 160
++ +L A T+ +K + K+ +L D+ E K +E L
Sbjct: 1222 EKEKSELKMEINDLASNMETV-SKAKANFEKMCR---TLEDQLSEIKTKEEEQQRLINEL 1277
Query: 161 MSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQL 220
+Q+ + T++ ++ + E D + S L + + F ++I ++ R+ ET A
Sbjct: 1278 SAQKARLHTESGEFS-RQLD-EKDAMVSQLSRGKQAFTQQIEEL---KRQLEEETKAKST 1332
Query: 221 RTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLS 280
L A D + +R+Q + R + R
Sbjct: 1333 LAHALQSARHDCDL----LREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTE 1388
Query: 281 RAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIK 340
E K +R+ E +E S+ SLE+T D ++ N ++
Sbjct: 1389 ELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERS-NAACIALD 1447
Query: 341 DNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYN 400
+ + + ++ S S + + +K+ ++ L +++
Sbjct: 1448 KKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKR--- 1504
Query: 401 DSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEH 460
E K LQ+ I DL + E + +L + K+ + K +Q LE + LEH
Sbjct: 1505 ----ENKNLQQEISDLTEQIAEGGKHIHELEKV---KKQLDHEKSELQTSLEEAEASLEH 1557
Query: 461 RKTEIEEYKRLLFEKGEEID-ELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXX 519
+ +I + L + EID ++ K +K
Sbjct: 1558 EEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALR 1617
Query: 520 RESQMKSYYEEL-MNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKL 578
+ +M+ E+ + L + Q E A NL + ++ + L + + Q++ E+L
Sbjct: 1618 IKKKMEGDLNEMEIQLNHANRQAAE--ALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQL 1675
Query: 579 QTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNK 626
E + + E L + E+ KM ++ + + LLH +
Sbjct: 1676 AMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQ 1723
Score = 40.3 bits (90), Expect = 0.023
Identities = 60/285 (21%), Positives = 119/285 (41%), Gaps = 30/285 (10%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLV 431
A+ + + K E+ AK E+E+K ++EK LQ + L ++E R L+
Sbjct: 854 ANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLI 913
Query: 432 RELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
+ + E+ + KE+ D E E+ KR L +E ELK K
Sbjct: 914 KTKIQLEAKI-------KEVTERAEDEEEINAELTAKKRKL---EDECSELK------KD 957
Query: 492 IKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQL-REFGAFDNL 550
I D+ E+++K+ EE+ L I +L +E A
Sbjct: 958 IDDLELTLAKVEKEKHAT-----------ENKVKNLTEEMAGLDETIAKLTKEKKALQEA 1006
Query: 551 N-DVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKML 609
+ + + + DK+ LTK + + ++++ E +++ + + E K E ++K+
Sbjct: 1007 HQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLA 1066
Query: 610 NEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEK 654
E + N L+ KL+ + E ++ + + +++L + L+K
Sbjct: 1067 QESTMDTENDKQQLNEKLK-KKEFEMSNLQGKIEDEQALAMQLQK 1110
Score = 35.9 bits (79), Expect = 0.49
Identities = 85/495 (17%), Positives = 177/495 (35%), Gaps = 23/495 (4%)
Query: 158 ESLMSQEKGISTKTLTMKIKEFNAENDLLKSS---LDQLRTEFLKEINDIIDCLRKNANE 214
E ++ + K L +I+E E + ++S ++ R++ +E+ +I + L +
Sbjct: 1101 EQALAMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGA 1160
Query: 215 TMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSI 274
T A K+ + E Q H A R
Sbjct: 1161 TSAQIELNKKREAEFQKMRRDLEESTLQ-HEAT---AAALRKKHADSVAELGKQIDSLQR 1216
Query: 275 MKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNK 334
+K +L + + +LK + + + +A++ + RT+ E+ + +N+
Sbjct: 1217 VKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINE 1276
Query: 335 LTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIE 394
L S + H E +R+ L A + + I+++K ++
Sbjct: 1277 L--SAQKARLHTESGEFSRQ-LDEKDAMVSQLSRGKQA-FTQQIEELKRQLEEETKAKST 1332
Query: 395 IEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQ-KELES 453
+ + + L+E ++ + E + + E+ + + ET + +ELE
Sbjct: 1333 LAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEE 1392
Query: 454 TKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXX 513
K L R + EE+ + K +++ K +L E ++D+
Sbjct: 1393 AKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNE--VEDLMIDVERSNAACIALDKKQ 1450
Query: 514 XXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEE 573
++ K YEE + + +Q L V N + D L E KR+
Sbjct: 1451 RNFDKVL-AEWKQKYEE-TQAELEASQKESRSLSTELFKVKNAYEESLDHL-ETLKRE-- 1505
Query: 574 YDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEA 633
++ LQ EI L E + E +++ EK K L+ ++ E + LE
Sbjct: 1506 -NKNLQ---QEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGK 1561
Query: 634 DIDVIITLAKYKKSL 648
+ + + L + K +
Sbjct: 1562 ILRIQLELNQVKSEI 1576
Score = 35.9 bits (79), Expect = 0.49
Identities = 88/489 (17%), Positives = 188/489 (38%), Gaps = 55/489 (11%)
Query: 175 KIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNT 234
K +E AE + + L TE K N ++ + L+ K L +SDL
Sbjct: 1463 KYEETQAELEASQKESRSLSTELFKVKN----AYEESLDHLETLKRENKNLQQEISDLTE 1518
Query: 235 QNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVV 294
Q AE K IH + + + S ++ L AE L+ +++
Sbjct: 1519 QIAEGGKHIHELEKVKKQLDHEK---------------SELQTSLEEAEASLEHEEGKIL 1563
Query: 295 QLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALARE 354
+++ L Q +SE ++R + + + + + ++ D ++
Sbjct: 1564 RIQLELNQVKSE---IDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKK 1620
Query: 355 KLQSXXXXXXXXXXXXSASYNKSIKDMKH--------EMNLNIAKLIEIEKKYNDSIEEK 406
K++ + ++++++++ +++L+ A + + K ++ E+
Sbjct: 1621 KMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVER 1680
Query: 407 KT--LQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTE 464
+ +Q +++LR L +E K +EL + ++ L +TK LE ++
Sbjct: 1681 RANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ 1740
Query: 465 IEEYKRLLFEKGEEIDELKSKLSTEKAI------KDIXXXXXXXXXXXXXXXXXXXXXXX 518
I+ + ++ +E K T+ A+ K+
Sbjct: 1741 IQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLR 1800
Query: 519 XRESQ---MKSYYEELMNLKNQITQLR---EFGAFDNLNDVGNMINQQRDKLFELTKRQE 572
E++ +K +++ L+ ++ +L E N+ V + +R ++ ELT + E
Sbjct: 1801 LGEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHER-RVKELTYQTE 1859
Query: 573 E----------YDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINL 622
E +KLQTK KR E EQ +V K ++++ E+ EE +I
Sbjct: 1860 EDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAEERADIAES 1919
Query: 623 LHNKLELRN 631
NKL +++
Sbjct: 1920 QVNKLRVKS 1928
>AB209708-1|BAD92945.1| 1574|Homo sapiens myosin, heavy polypeptide
7, cardiac muscle, beta variant protein.
Length = 1574
Score = 47.6 bits (108), Expect = 2e-04
Identities = 51/265 (19%), Positives = 110/265 (41%), Gaps = 13/265 (4%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLV 431
AS + +K + + A+ E+E+K ++EK LQ + + +L ++E R L+
Sbjct: 489 ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLI 548
Query: 432 R-------ELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDEL-K 483
+ ++ E LE ++ + EL + K LE E E KR + + + ++ K
Sbjct: 549 KNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLE---DECSELKRDIDDLELTLAKVEK 605
Query: 484 SKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLRE 543
K +TE +K++ + + E + N +T+ +
Sbjct: 606 EKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAE-EDKVNTLTKAK- 663
Query: 544 FGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKE 603
++D+ + Q++ +L + + + + L+ + I L + + L KK+
Sbjct: 664 VKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKD 723
Query: 604 KEIKMLNEKEEEHMNIINLLHNKLE 628
E+ LN + E+ + + L KL+
Sbjct: 724 FELNALNARIEDEQALGSQLQKKLK 748
Score = 47.6 bits (108), Expect = 2e-04
Identities = 91/493 (18%), Positives = 184/493 (37%), Gaps = 25/493 (5%)
Query: 149 KRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCL 208
K ++ ++ E + QEK + K ++ + L + S+ L + K+ D + L
Sbjct: 665 KLEQQVDDLEGSLEQEKKVRMDLERAK-RKLEGDLKLTQESIMDLEND--KQQLD--ERL 719
Query: 209 RKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXX 268
+K E AL R ++ S L + E++ +I + A R
Sbjct: 720 KKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELE-AERTARAKVEKLRSDL 778
Query: 269 XXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDF 328
+ +RL A +E + EA ++ R + LE +
Sbjct: 779 SRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRD---LEEATLQHEATAAALRKKH 835
Query: 329 DQELNKLTQSIKDNTTHLEDIALAREKLQ-----SXXXXXXXXXXXXSASYNKSIKDMKH 383
+ +L + I DN ++ L +EK + A+ K + ++
Sbjct: 836 ADSVAELGEQI-DNLQRVKQ-KLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLED 893
Query: 384 EMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVR-ELDEKESILE 442
+MN + +K E ++ ND ++ LQ +L L E E + L R +L + + +
Sbjct: 894 QMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLED 953
Query: 443 TKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS--TEKAIKDIXXXXX 500
K+ +++E+++ K L H LL E+ EE E K++L KA ++
Sbjct: 954 LKRQLEEEVKA-KNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT 1012
Query: 501 XXXXXXXXXXXXXXXXXXXRESQMKSYYE--ELMNLKNQITQLREFGAFDNLNDVGNMIN 558
+++ E E +N K + + + + D+ +
Sbjct: 1013 KYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVE 1072
Query: 559 QQRDKLFELTKRQEEYDEKL---QTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEE 615
+ L K+Q +D+ L + K E + +ES ++ L+ + ++K E+ E
Sbjct: 1073 RSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLE 1132
Query: 616 HMNIINLLHNKLE 628
H+ + L+
Sbjct: 1133 HLETFKRENKNLQ 1145
Score = 45.2 bits (102), Expect = 8e-04
Identities = 49/269 (18%), Positives = 119/269 (44%), Gaps = 4/269 (1%)
Query: 389 IAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQ 448
+ K E EK+ EE L+E ++ E E ++ L++E ++ + ++ +Q
Sbjct: 478 LLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL 537
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA-IKDIXXXXXXXXXXXX 507
+ E L K ++E + + E+ E+ +E+ ++L+ +K ++D
Sbjct: 538 ADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLE 597
Query: 508 XXXXXXXXXXXXRESQMKSYYEELMNLKNQITQL-REFGAFDNLNDVG-NMINQQRDKLF 565
E+++K+ EE+ L I +L +E A + + + + DK+
Sbjct: 598 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVN 657
Query: 566 ELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHN 625
LTK + + ++++ E +++ + + E K E ++K+ E + N L
Sbjct: 658 TLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDE 717
Query: 626 KLELRNEADIDVIITLAKYKKSLTLVLEK 654
+L+ + + +++ + + +++L L+K
Sbjct: 718 RLK-KKDFELNALNARIEDEQALGSQLQK 745
Score = 41.1 bits (92), Expect = 0.013
Identities = 109/628 (17%), Positives = 234/628 (37%), Gaps = 42/628 (6%)
Query: 14 DGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTH 73
+G L L+E+E++ S+ +T+ K + +++ E K++LE+ L +L++
Sbjct: 923 NGELSRQLDEKEALISQ---LTRGKLTYTQQL---EDLKRQLEEEVKAKNALAHALQSAR 976
Query: 74 RKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLL 133
LL ++ + + + V + ++ Q E A++ + + + + L
Sbjct: 977 HDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1036
Query: 134 NIPNSLVD----KCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSS 189
V+ KC + + N E LM + + + K+ N D + +
Sbjct: 1037 QEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNF--DKILAE 1094
Query: 190 LDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHH 249
Q E E+ R + E L+ +E L +N ++++I
Sbjct: 1095 WKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQ 1154
Query: 250 RPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWS 309
+ + + + L AE L+ ++++ + Q ++E
Sbjct: 1155 LGSSGKTIHELEKVRKQLEAEKMEL-QSALEEAEASLEHEEGKILRAQLEFNQIKAE--- 1210
Query: 310 LERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXX 369
+ER + + + ++ L S+ T + ++K++
Sbjct: 1211 IERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSH 1270
Query: 370 XSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKD 429
+ ++ K +K +L L + + + +D++ L+ENI + E R
Sbjct: 1271 ANRMAAEAQKQVKSLQSL----LKDTQIQLDDAVRANDDLKENIAIV-------ERRNNL 1319
Query: 430 LVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
L EL+E +++E + +K E + R + L + +++D S+L TE
Sbjct: 1320 LQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTE 1379
Query: 490 KAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEEL-MNLKNQITQLREFGAFD 548
+E ++ E + N++ I L+ D
Sbjct: 1380 VEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQH--RLD 1437
Query: 549 NLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM 608
+ + + +L +L R E + +L E E KR ES+ + K E+ IK
Sbjct: 1438 EAEQIA--LKGGKKQLQKLEARVRELENEL---EAEQKRNAESVKG----MRKSERRIKE 1488
Query: 609 LN-EKEEEHMNIINL--LHNKLELRNEA 633
L + EE+ N++ L L +KL+L+ +A
Sbjct: 1489 LTYQTEEDRKNLLRLQDLVDKLQLKVKA 1516
Score = 39.1 bits (87), Expect = 0.053
Identities = 84/477 (17%), Positives = 183/477 (38%), Gaps = 37/477 (7%)
Query: 22 NEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQ 81
+ Q+ S S ++ KLK ++E + E K+E ++ Q ++ +L L ++ + + L +
Sbjct: 1108 SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEK 1167
Query: 82 KVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLDNKVTFDVNKLLNIPNSLVD 141
AE++ + + + + L E K L N++ ++ + L + +
Sbjct: 1168 VRKQLEAEKMELQSALEEAEASL----EHEEGKILRAQLEFNQIKAEIERKLAEKD---E 1220
Query: 142 KCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIK---EFNAENDLLKSSLDQLRTEFL 198
+ E+ +++ ++ + E + L +K K + N E ++ S +++ E
Sbjct: 1221 EMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN-EMEIQLSHANRMAAEAQ 1279
Query: 199 KEINDIIDCLRK---------NANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHH 249
K++ + L+ AN+ + + E L L + E+R + +
Sbjct: 1280 KQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNL--LQAELEELRAVVEQTERS 1337
Query: 250 RPYANRNXXXXXXXXXXXXXXXXSIM--KDRLSRAEHQLKTNVERVVQLEAALEQARSES 307
R A + S++ K ++ QL+T VE VQ E+ ++
Sbjct: 1338 RKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKA 1397
Query: 308 WSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHL---EDIAL--AREKLQSXXXX 362
+ + ++ + Q+IKD L E IAL +++LQ
Sbjct: 1398 ITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEAR 1457
Query: 363 XXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLE 422
A ++ + +K M + ++ E+ + + + LQ+ +D L
Sbjct: 1458 VRELENELEAEQKRNAESVK-GMRKSERRIKELTYQTEEDRKNLLRLQDLVDKL------ 1510
Query: 423 SELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI 479
+L+VK R+ +E E T ++++ + E R E L K +I
Sbjct: 1511 -QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDI 1566
>AB035898-1|BAB03309.1| 1388|Homo sapiens kinesin-like protein 2
protein.
Length = 1388
Score = 47.6 bits (108), Expect = 2e-04
Identities = 114/599 (19%), Positives = 236/599 (39%), Gaps = 80/599 (13%)
Query: 56 EDRQNQVMELYASLRNT---HRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGE 112
E + Q++++ L N+ + + K L +K L EL + A L+ E LL+ A
Sbjct: 582 EKLKAQLLQIQTELNNSKQEYEEFKELTRKRQLELESELQSLQKANLNLENLLE--ATKA 639
Query: 113 PKALEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTL 172
K E S L NK+ + K++ P + K + F SL +Q I
Sbjct: 640 CKRQEVSQL-NKIHAETLKIITTPTKAYQLHSRPVPKLSPEMGSFGSLYTQNSSI----- 693
Query: 173 TMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDL 232
+ND+L + E+N+ + E +Q + L L +
Sbjct: 694 --------LDNDILNEPVPP-------EMNE--QAFEAISEELRTVQEQMSALQAKLDEE 736
Query: 233 NTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVER 292
+N ++++ + +HH S +L+ E QL+ +
Sbjct: 737 EHKNLKLQQHVDKLEHHSTQMQELFSSERIDWTKQQEELLS----QLNVLEKQLQETQTK 792
Query: 293 VVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALA 352
L++ + R S ++ + + ++E NKL++ L+++ L
Sbjct: 793 NDFLKSEVHDLRVVLHSADKELSSVKLEYSSFKTNQEKEFNKLSERHMHVQLQLDNLRLE 852
Query: 353 REK--------------LQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKK 398
EK LQ ++ K + +K ++N N+ +L+E EK+
Sbjct: 853 NEKLLESKACLQDSYDNLQEIMKFEIDQLSRNLQNFKKENETLKSDLN-NLMELLEAEKE 911
Query: 399 YNDSI-----EEK----KTLQENIDDLRTDLLESELRVKDLVRELDE-KESILETKQCV- 447
N+ + E+K K + + ++ +R + + + + + ++ + +ES+L T++ +
Sbjct: 912 RNNKLSLQFEEDKENSSKEILKVLEAVRQEKQKETAKCEQQMAKVQKLEESLLATEKVIS 971
Query: 448 --QKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXX 505
+K +S K + +I+E + + EK E ID LK +L KDI
Sbjct: 972 SLEKSRDSDKKVVADLMNQIQELRTSVCEKTETIDTLKQEL------KDINCKYNSALVD 1025
Query: 506 XXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLF 565
+K ++++LK + +LR + + + ++L
Sbjct: 1026 REESRVL-----------IKKQEVDILDLKETL-RLRILSEDIERDMLCEDLAHATEQLN 1073
Query: 566 ELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLH 624
LT+ +++ LQ+ + E+ + + E +H LN+K++E++ +K E + + L H
Sbjct: 1074 MLTEASKKHSGLLQSAQEELTKKEALIQELQHKLNQKKEEVE--QKKNEYNFKMRQLEH 1130
Score = 46.8 bits (106), Expect = 3e-04
Identities = 57/294 (19%), Positives = 126/294 (42%), Gaps = 17/294 (5%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLE-SELRVKDLVREL 434
++ + + E+ ++ ++ K ++ + LQ+++D L + EL + +
Sbjct: 710 QAFEAISEELRTVQEQMSALQAKLDEEEHKNLKLQQHVDKLEHHSTQMQELFSSERIDWT 769
Query: 435 DEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA--I 492
++E +L ++K+L+ T+T + K+E+ + + +L +E+ +K + S+ K
Sbjct: 770 KQQEELLSQLNVLEKQLQETQTKNDFLKSEVHDLRVVLHSADKELSSVKLEYSSFKTNQE 829
Query: 493 KDIXXXXXXXXXXXXXXXXXXXXXXXXRESQ--MKSYYEELMN-LKNQITQLREFGAFDN 549
K+ ES+ ++ Y+ L +K +I QL N
Sbjct: 830 KEFNKLSERHMHVQLQLDNLRLENEKLLESKACLQDSYDNLQEIMKFEIDQLSR--NLQN 887
Query: 550 LNDVGNMINQQRDKLFELTKRQEEYDEKL-----QTKEN---EIKRLVESMTEQEHVLNK 601
+ + L EL + ++E + KL + KEN EI +++E++ +++
Sbjct: 888 FKKENETLKSDLNNLMELLEAEKERNNKLSLQFEEDKENSSKEILKVLEAVRQEKQKETA 947
Query: 602 KEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSL-TLVLEK 654
K ++ +K EE + + + LE ++D V+ L + L T V EK
Sbjct: 948 KCEQQMAKVQKLEESLLATEKVISSLEKSRDSDKKVVADLMNQIQELRTSVCEK 1001
Score = 39.5 bits (88), Expect = 0.040
Identities = 55/261 (21%), Positives = 120/261 (45%), Gaps = 18/261 (6%)
Query: 395 IEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELEST 454
I+K+ D ++ K+TL+ I L D+ E ++ +DL ++ + E + L+S
Sbjct: 1033 IKKQEVDILDLKETLRLRI--LSEDI-ERDMLCEDLAHATEQLNMLTEASKKHSGLLQSA 1089
Query: 455 KTDLEHRKTEIEEYKRLLFEKGEEIDELKS----KLSTEKAIKDIXXXXXXXXXXXXXXX 510
+ +L ++ I+E + L +K EE+++ K+ K+ + + D
Sbjct: 1090 QEELTKKEALIQELQHKLNQKKEEVEQKKNEYNFKMRQLEHVMDSAAEDPQSPKTPPHFQ 1149
Query: 511 XXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKR 570
+E +++ +L++ +T+L E N ++ M Q R+ + L
Sbjct: 1150 THLAKLLETQEQEIEDGRASKTSLEHLVTKLNEDREVKNA-EILRMKEQLRE-MENLRLE 1207
Query: 571 QEEYDEK---LQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKL 627
++ EK LQ + ++IKR E+ ++Q H N++ K + E +E + ++ L
Sbjct: 1208 SQQLIEKNWLLQGQLDDIKRQKEN-SDQNHPDNQQLKNEQ--EESIKERLAKSKIVEEML 1264
Query: 628 ELRNEADIDVIITLAKYKKSL 648
+++ AD++ + + A Y K +
Sbjct: 1265 KMK--ADLEEVQS-ALYNKEM 1282
Score = 31.9 bits (69), Expect = 8.0
Identities = 53/251 (21%), Positives = 107/251 (42%), Gaps = 30/251 (11%)
Query: 3 QEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQV 62
QE++ Q + D +++L Q+ + H T+++ ++ + + + K ++EL + N V
Sbjct: 723 QEQMSALQAKLDEEEHKNLKLQQHVDKLEHHSTQMQELFSSERIDWTKQQEELLSQLN-V 781
Query: 63 MELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTLD 122
+E L+ T K L E+H + V S ++ L LE+S+
Sbjct: 782 LE--KQLQETQTKNDFL--------KSEVHDLRVVLHSADKELSSVK------LEYSSFK 825
Query: 123 NKVTFDVNKL--------LNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTM 174
+ NKL L + N ++ E+ L + + + +++L K L+
Sbjct: 826 TNQEKEFNKLSERHMHVQLQLDNLRLEN-EKLLESKACLQDSYDNLQEIMK-FEIDQLSR 883
Query: 175 KIKEFNAENDLLKSSLDQLR--TEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDL 232
++ F EN+ LKS L+ L E KE N+ + + E + ++ K L +
Sbjct: 884 NLQNFKKENETLKSDLNNLMELLEAEKERNNKLSLQFEEDKENSSKEI-LKVLEAVRQEK 942
Query: 233 NTQNAEMRKQI 243
+ A+ +Q+
Sbjct: 943 QKETAKCEQQM 953
>AB028997-1|BAA83026.2| 1715|Homo sapiens KIAA1074 protein protein.
Length = 1715
Score = 47.6 bits (108), Expect = 2e-04
Identities = 98/537 (18%), Positives = 205/537 (38%), Gaps = 39/537 (7%)
Query: 128 DVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDL-L 186
DV+ L + + CE K + E L + K S L ++ + E L L
Sbjct: 688 DVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMECKD-SVSLLKIQDAALSCERLLEL 746
Query: 187 KSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSG 246
K + +L T +K++ D ++ L++ +ET KE+ S L Q E +++ S
Sbjct: 747 KKNHCELLTVKIKKMEDKVNVLQRELSET-------KEIK---SQLEHQKVEWERELCS- 795
Query: 247 DHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSE 306
R ++++L R E Q + VE QLE +L+ E
Sbjct: 796 -------LRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEME 848
Query: 307 SWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHL---EDIALAREKLQSXXXXX 363
+++ + +E N T HL ++I +A++K+ S
Sbjct: 849 LRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHS 908
Query: 364 XXXXXXXSASYNKSIKDMKHEMNLNIAKLI-EIEKKYNDSIEEKKTLQENIDDLRTDLLE 422
S N +++ + L I + + ++K E+ K ++E +DL+ + +
Sbjct: 909 HEEEKDLSHK-NSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQ 967
Query: 423 SELRVKDLVRELDEKESILETKQC-VQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE 481
+E + + + + + S+L + + +LE+ K E + E+E Y L + D+
Sbjct: 968 NEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQ 1027
Query: 482 LK-SKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQ 540
+ SK E A + Q+ +L +L+ +
Sbjct: 1028 SETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHH 1087
Query: 541 LREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLN 600
R D L + + + + L + + +E ++K Q ++ ++ + + E L+
Sbjct: 1088 TR-----DALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLS 1142
Query: 601 KKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSI 657
+ + E +L ++ ++ HNK + + + I++ + L EK S+
Sbjct: 1143 QLQSENMLLRQQLDD-------AHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSL 1192
Score = 35.5 bits (78), Expect = 0.65
Identities = 104/519 (20%), Positives = 199/519 (38%), Gaps = 49/519 (9%)
Query: 2 KQEELEIQQNQTDGCLYEDLNEQESITSE-SHKITKLKTVWQEKMVTFEKSKKELEDRQN 60
K LEI+ + T L E E + + S ++K + Q+ K K + +Q
Sbjct: 1077 KLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYI-GKQE 1135
Query: 61 QVMELYASLRNTHRKMKL-LGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHS 119
V E + L++ + ++ L N +E ++N+ + +L A E ++L
Sbjct: 1136 SVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLE 1195
Query: 120 TLDNKVTFDVNKLLNIPNSLV-DKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKE 178
+ ++ + N L +K E + R+ ++L Q ++ +T + +
Sbjct: 1196 ERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYR- 1254
Query: 179 FNAENDL--LKSSLDQLRTEFLKEIND----IIDCLRKNANETMALQLRTKELSCALSDL 232
N E++ LK L Q+R + L+E D + C K + L+ +L +
Sbjct: 1255 INLEDETQDLKKKLGQIRNQ-LQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQ 1313
Query: 233 NTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVE- 291
+ E++K + N N ++ L + ++K NVE
Sbjct: 1314 MDKIEELQKNL---------LNANLSEDEKEQLKKLMELKQSLECNL---DQEMKKNVEL 1361
Query: 292 --RVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDI 349
+ + L+ R + E + D ++NKL I D T LE
Sbjct: 1362 EREITGFKNLLKMTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETA 1421
Query: 350 ALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNL-----NIAKLIE---IE----K 397
L + K K K++ L N+ IE +E K
Sbjct: 1422 GSKCLHLDTKNQILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVK 1481
Query: 398 KYNDSIEEK--KTLQENIDDLRTDLLESELRVKDLVRELDEK-----ESILETK-QCVQK 449
+Y IEE+ + + E + ++ L+++ ++ + + E +S +E + + ++
Sbjct: 1482 QYKQEIEERARQEIAEKLKEVNL-FLQAQAASQENLEQFRENNFASMKSQMELRIKDLES 1540
Query: 450 ELESTKTDLEH-RKTEIEEYKRLLFEKGEEIDELKSKLS 487
EL KT E KTE+E+YK+L E+ + L SKL+
Sbjct: 1541 ELSKIKTSQEDFNKTELEKYKQLYLEELKVRKSLSSKLT 1579
Score = 33.9 bits (74), Expect = 2.0
Identities = 26/119 (21%), Positives = 58/119 (48%), Gaps = 5/119 (4%)
Query: 567 LTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEI----KMLNEKEEEHMNIINL 622
LT + ++ ++K+ + E+ E ++ EH + E+E+ LN++EE+ N +
Sbjct: 754 LTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRN-ADT 812
Query: 623 LHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRTLRKNMS 681
L+ K+ + + + K+ L L L+ + + R +K +L VV + ++ +S
Sbjct: 813 LYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLS 871
>X64838-1|CAA46050.1| 1427|Homo sapiens restin protein.
Length = 1427
Score = 47.2 bits (107), Expect = 2e-04
Identities = 122/655 (18%), Positives = 254/655 (38%), Gaps = 66/655 (10%)
Query: 3 QEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVT-FEKSKK----ELED 57
Q E+E QNQ D E E++ ++ K+ K K E + + +K++ E+ED
Sbjct: 660 QHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMED 719
Query: 58 RQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALE 117
N++ E + +++++L K N + + + K + E+LL L AL
Sbjct: 720 TLNKLQEAEIKV----KELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDL------DALR 769
Query: 118 HSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTK--TLTMK 175
++ + K ++ KL + + + ++ + S+ + +G K L
Sbjct: 770 KASSEGK--SEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQEN 827
Query: 176 IKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLN-- 233
+ E + + L+ L L+ +F + + + R L + ++ + SDL
Sbjct: 828 LSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKL 887
Query: 234 TQN-AEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVER 292
+N A+M + D + +L++ +L+
Sbjct: 888 RENLADMEAKFREKDEREEQLIK-AKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERD 946
Query: 293 VVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALA 352
V +L+ L +A + L++++ E QE K + K +++
Sbjct: 947 VEELQLKLTKANENASFLQKSI----EDMTVKAEQSQQEAAKKHEEEK------KELERK 996
Query: 353 REKLQSXXXXXXXXXXXXSASYNKSIKD--MKHEMNL-NIAK-LIEIEKKYNDSIEEKKT 408
L+ A Y ++ + KHE L N+ K L++ E K + EE
Sbjct: 997 LSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSG 1056
Query: 409 LQENIDDLR--TDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIE 466
L + +++LR D ++ +D ++ + E + + K LE TK + E++
Sbjct: 1057 LLQELEELRKQADKAKAAQTAEDAMQIM---EQMTKEKTETLASLEDTKQTNAKLQNELD 1113
Query: 467 EYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKS 526
K + EE+++ K L+ E + + Q+ +
Sbjct: 1114 TLKENNLKNVEELNKSKELLTVENQKME----------EFRKEIETLKQAAAQKSQQLSA 1163
Query: 527 YYEELMNLKNQITQLR-EFGAFDNLNDVGNMINQQRDKLFELTKRQEEY----DEKLQTK 581
EE + L ++ + R E + L + +++N Q L E+ KR+ ++ DE+ +
Sbjct: 1164 LQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQ---LLEMKKRESKFIKDADEEKASL 1220
Query: 582 ENEIKRLVESMTEQEHVLNKKEKEIKML---NEKEEEHMNIINLLHN---KLELR 630
+ I +TE++ L K E+ +L N + +++ L + KLEL+
Sbjct: 1221 QKSISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELK 1275
Score = 38.7 bits (86), Expect = 0.070
Identities = 56/226 (24%), Positives = 102/226 (45%), Gaps = 20/226 (8%)
Query: 409 LQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLE-HRKTE--- 464
L+ +D LRT + ++ +L+ +L+E++ +E Q +E TK DLE K E
Sbjct: 406 LEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHAR 465
Query: 465 IEEYKR-LLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQ 523
I+E ++ LLFEK + D+L+ +L + R
Sbjct: 466 IKELEQSLLFEK-TKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLES 524
Query: 524 MKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKEN 583
K + M+L + L+E + +V +Q+ E+T +E + + +T +
Sbjct: 525 NKPAGDVDMSL----SLLQEISSLQEKLEVTRTDHQR-----EITSLKEHFGAREETHQK 575
Query: 584 EIKRLVESMTEQEHVLNKKEKEIK-MLNEKEEEHMNIINLLHNKLE 628
EIK L + TE+ L+K+ + +K L +E+ ++I L +KLE
Sbjct: 576 EIKALY-TATEK---LSKENESLKSKLEHANKENSDVIALWKSKLE 617
Score = 36.3 bits (80), Expect = 0.37
Identities = 51/237 (21%), Positives = 88/237 (37%), Gaps = 8/237 (3%)
Query: 431 VRELDEKESILETK-QCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
V EL+ K L T + +E LE K ++E+ + + E+ +L+++ E
Sbjct: 403 VLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLE 462
Query: 490 KA-IKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFD 548
A IK++ S+ E +L ++ ++ E
Sbjct: 463 HARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRL 522
Query: 549 NLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM 608
N ++ L E++ QE+ + + EI L E +E +KEIK
Sbjct: 523 ESNKPAGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREET---HQKEIKA 579
Query: 609 LNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVLKCS 665
L E+ L +KLE N+ + DVI A +K L + + LK S
Sbjct: 580 LYTATEKLSKENESLKSKLEHANKENSDVI---ALWKSKLETAIASHQQAMEELKVS 633
>U53445-1|AAA98972.1| 752|Homo sapiens DOC1 protein.
Length = 752
Score = 47.2 bits (107), Expect = 2e-04
Identities = 44/222 (19%), Positives = 95/222 (42%), Gaps = 7/222 (3%)
Query: 279 LSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQS 338
L + E + + L+ LE+ R + L + + E + L K +
Sbjct: 173 LEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKVRIKEL-EAIESRLEKTEFT 231
Query: 339 IKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEK- 397
+K++ T L+ + + + + + ++ ++++ KLIE K
Sbjct: 232 LKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKR 291
Query: 398 --KYNDSIEEKK-TLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELEST 454
K +EEK ++ + DDL+ L E + DL+ ++ ++ L++ + ++K+
Sbjct: 292 ALKSKTDVEEKMYSVTKERDDLKNKLKAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKN 351
Query: 455 KTDLEHRK--TEIEEYKRLLFEKGEEIDELKSKLSTEKAIKD 494
K + + K T + + + E +E++ LK KL KAI+D
Sbjct: 352 KLNQDSGKSTTALHQENNKIKELSQEVERLKLKLKDMKAIED 393
Score = 36.3 bits (80), Expect = 0.37
Identities = 69/347 (19%), Positives = 138/347 (39%), Gaps = 29/347 (8%)
Query: 151 KEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKS---SLDQLRTEFLKEINDIIDC 207
+E+I E K + +TL + K+F E + L +L++L F K +
Sbjct: 133 EELIKMEEQCRDLNKRLERETL--QSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYS- 189
Query: 208 LRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXX 267
L+ N + ++ TK+LS L L + E+ + I S + +
Sbjct: 190 LKCNLEKE---RMTTKQLSQELESLKVRIKEL-EAIESRLEKTEFTLKEDLTKLKTLTVM 245
Query: 268 XXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXED 327
M ++L + E +L+ + L+ +++ ++ + D
Sbjct: 246 FVDERKTMSEKLKKTEDKLQA-------ASSQLQVEQNKVTTVTEKLIEETKRALKSKTD 298
Query: 328 FDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKD-MKHEMN 386
++++ +T+ D L+ A E+ + S KD +K+++N
Sbjct: 299 VEEKMYSVTKERDDLKNKLK----AEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLN 354
Query: 387 LNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQC 446
+ K + N+ I+E L + ++ L+ L + + DL++ DE E++
Sbjct: 355 QDSGKSTTALHQENNKIKE---LSQEVERLKLKLKDMKAIEDDLMKTEDEYETLERRYAN 411
Query: 447 VQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE--LKSKLSTEKA 491
+ + + +LEH K E+ +YK L EK E E L +L E+A
Sbjct: 412 ERDKAQFLSKELEHVKMELAKYK--LAEKTETSHEQWLFKRLQEEEA 456
Score = 33.5 bits (73), Expect = 2.6
Identities = 63/360 (17%), Positives = 134/360 (37%), Gaps = 18/360 (5%)
Query: 285 QLKTNVERV-VQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNT 343
+L TN + +L A + + E R +D D + KLT N
Sbjct: 22 ELTTNAKETHTKLALAEARVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDSQNR 81
Query: 344 THLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSI 403
+ +A ++ + K K E N + E+E+
Sbjct: 82 QLQQKLAALSRQIDELEETNRSLRKAEEELQDIKEKISKGEYG-NAGIMAEVEELIKME- 139
Query: 404 EEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKT 463
E+ + L + ++ + +L V+ L + + E + + ++E S K +LE +
Sbjct: 140 EQCRDLNKRLERETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERM 199
Query: 464 EIEEYKRLLFE---KGEEIDELKSKLS-TEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXX 519
++ + L + +E++ ++S+L TE +K+
Sbjct: 200 TTKQLSQELESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKK 259
Query: 520 RESQMKSYYEELMNLKNQITQLREF------GAFDNLNDVGNM---INQQRDKLFELTKR 570
E ++++ +L +N++T + E A + DV + ++RD L K
Sbjct: 260 TEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERDDLKNKLKA 319
Query: 571 QEEYDEKLQTKENEIKRLVESM--TEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
+EE L ++ N +K ++S+ E++ + NK ++ + N I L ++E
Sbjct: 320 EEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTTALHQENNKIKELSQEVE 379
>M97501-1|AAA35693.1| 1392|Homo sapiens cytoplasmic linker protein-170
alpha-2 protein.
Length = 1392
Score = 47.2 bits (107), Expect = 2e-04
Identities = 121/653 (18%), Positives = 249/653 (38%), Gaps = 62/653 (9%)
Query: 3 QEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVT-FEKSKK----ELED 57
Q E+E QNQ D E E++ ++ K+ K K E + + +K++ E+ED
Sbjct: 625 QHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMED 684
Query: 58 RQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALE 117
N++ E + +++++L K N + + + K + E+LL L AL
Sbjct: 685 TLNKLQEAEIKV----KELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDL------DALR 734
Query: 118 HSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTK--TLTMK 175
++ + K ++ KL + + + ++ + S+ + +G K L
Sbjct: 735 KASSEGK--SEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQEN 792
Query: 176 IKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLN-- 233
+ E + + L+ L L+ +F + + + R L + ++ + SDL
Sbjct: 793 LSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKL 852
Query: 234 TQN-AEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVER 292
+N A+M + D + +L++ +L+
Sbjct: 853 RENLADMEAKFREKDEREEQLIK-AKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERD 911
Query: 293 VVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALA 352
V +L+ L +A + L++++ E QE K + K +++
Sbjct: 912 VEELQLKLTKANENASFLQKSI----EDMTVKAEQSQQEAAKKHEEEK------KELERK 961
Query: 353 REKLQSXXXXXXXXXXXXSASYNKSIKD--MKHEMNL-NIAK-LIEIEKKYNDSIEEKKT 408
L+ A Y ++ + KHE L N+ K L++ E K + EE
Sbjct: 962 LSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSG 1021
Query: 409 LQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEY 468
L + +++LR E + + E + + K LE TK + E++
Sbjct: 1022 LLQELEELRKQ-AEKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTL 1080
Query: 469 KRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYY 528
K + EE+++ K L+ E + + Q+ +
Sbjct: 1081 KENNLKNVEELNKSKELLTVENQKME----------EFRKEIETLKQAAAQKSQQLSALQ 1130
Query: 529 EELMNLKNQITQLR-EFGAFDNLNDVGNMINQQRDKLFELTKRQEEY----DEKLQTKEN 583
EE + L ++ + R E + L + +++N Q L E+ KR+ ++ DE+ + +
Sbjct: 1131 EENVKLAEELGRSRDEVTSHQKLEEERSVLNNQ---LLEMKKRESKFIKDADEEKASLQK 1187
Query: 584 EIKRLVESMTEQEHVLNKKEKEIKML---NEKEEEHMNIINLLHN---KLELR 630
I +TE++ L K E+ +L N + +++ L + KLEL+
Sbjct: 1188 SISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELK 1240
Score = 38.7 bits (86), Expect = 0.070
Identities = 26/91 (28%), Positives = 49/91 (53%), Gaps = 4/91 (4%)
Query: 409 LQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLE----HRKTE 464
L+ +D LRT + ++ +L+ +L+E++ +E Q +E TK DLE K+
Sbjct: 406 LEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSR 465
Query: 465 IEEYKRLLFEKGEEIDELKSKLSTEKAIKDI 495
I E ++ L + +E+ EL+ +L + K D+
Sbjct: 466 IMELEKDLALRVQEVAELRRRLESNKPAGDV 496
>BX537964-1|CAD97928.1| 898|Homo sapiens hypothetical protein
protein.
Length = 898
Score = 47.2 bits (107), Expect = 2e-04
Identities = 64/320 (20%), Positives = 132/320 (41%), Gaps = 29/320 (9%)
Query: 375 NKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVREL 434
NK ++ + E + K + EK+ D +EK+TL++ + D +L ++ ++K L +E
Sbjct: 298 NKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKNTNKIKQLSQEK 357
Query: 435 DEKESILETKQ----CVQKELESTKTDLEHRKTEIE----EYKRLLFEKGEEIDELK--- 483
+ ETK+ + +E++ K D+ +++ + K + E D+LK
Sbjct: 358 GRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKETKDKLKETT 417
Query: 484 SKLSTEKAIKD---------IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNL 534
+KL+ K D I E QM+ ++L
Sbjct: 418 TKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMH 477
Query: 535 KNQITQLREF-----GAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRL- 588
+I +L + D L + + D+ +Y E + ++ EI+ L
Sbjct: 478 HAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLL 537
Query: 589 --VESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVII-TLAKYK 645
V++ + + L + ++EI+ L E+ E ++IN L +E + + ++++ T
Sbjct: 538 DKVKTADQLQEQLQRGKQEIENLKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTS 597
Query: 646 KSLTLVLEKMSISNRVLKCS 665
K+ L E S+ ++ K S
Sbjct: 598 KNAQLQSESNSLQSQFDKVS 617
Score = 44.4 bits (100), Expect = 0.001
Identities = 57/288 (19%), Positives = 123/288 (42%), Gaps = 17/288 (5%)
Query: 375 NKSIKDMKHEMNL-NIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRE 433
NK +K + ++ ++ +++ + + + + + ++ R E E V VR
Sbjct: 262 NKEVKASRDQLIAQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQ---EKEAMVMKYVRG 318
Query: 434 LDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGE--EIDELKSKLSTEKA 491
E + + K+ ++K+L +LE +I K+L EKG ++ E K T +
Sbjct: 319 EKESLDLRKEKETLEKKLRDANKELEKNTNKI---KQLSQEKGRLHQLYETKEG-ETTRL 374
Query: 492 IKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLN 551
I++I +S K ++L ++TQ +E A
Sbjct: 375 IREIDKLKEDINSHVIKVKWAQNKLKAEMDSH-KETKDKLKETTTKLTQAKE-EADQIRK 432
Query: 552 DVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNE 611
+ +MI ++ E+ + E D KL+ + E+++ ++ ++Q + + K KE++ L
Sbjct: 433 NCQDMIKTYQESE-EI--KSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKR 489
Query: 612 KEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISN 659
+E M+ + L K++ + + L+KYK+ + +K I N
Sbjct: 490 TFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIIN--RQKAEIQN 535
Score = 42.7 bits (96), Expect = 0.004
Identities = 128/708 (18%), Positives = 272/708 (38%), Gaps = 61/708 (8%)
Query: 8 IQQNQTDGCLYEDL-NEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELY 66
I++N+ L+ D+ +E++++ E K T+ + ++ M T ++ + +E+ +V
Sbjct: 213 IKENKKHQELFVDICSEKDNLREELKKRTETE---KQHMNTIKQLESRIEELNKEVKASR 269
Query: 67 ASLRNTHRKMKLLGQKVNLPSAEELHIMNV----AKLSPEQLLQLCAGGEPKAL----EH 118
L K Q+++ A+ + N A+ E ++ GE ++L E
Sbjct: 270 DQLIAQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEK 329
Query: 119 STLDNKVTFDVNKLLNIPNSLVDKCEET------LFKRKE--IINWFESLMSQEKGISTK 170
TL+ K+ D NK L + + + + L++ KE + ++ I++
Sbjct: 330 ETLEKKLR-DANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSH 388
Query: 171 TLTMKIKE--FNAENDLLKSSLDQLR--TEFLKEINDIIDCLRKNANETMALQLRTKELS 226
+ +K + AE D K + D+L+ T L + + D +RKN + + ++E+
Sbjct: 389 VIKVKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIK 448
Query: 227 CALSD--LNTQNAEMRKQIH--SGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRA 282
D L E+ KQ+ S +A ++ ++
Sbjct: 449 SNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCL 508
Query: 283 EHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDN 342
E + + + + + + + ++E +L V QE+ L + ++
Sbjct: 509 EDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRG-KQEIENLKEEVESL 567
Query: 343 TTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDS 402
+ + D+ E + + S N ++ + + K+ E +
Sbjct: 568 NSLINDLQKDIEGSRKRESELLLFTERLT-SKNAQLQSESNSLQSQFDKVSCSESQLQSQ 626
Query: 403 IEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRK 462
E+ K Q NI+ LES L ++ +R+ +E +++ C Q E+++ T +E K
Sbjct: 627 CEQMK--QTNIN------LESRLLKEEELRK-EEVQTLQAELACRQTEVKALSTQVEELK 677
Query: 463 TEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRES 522
E+ +R + I +L +L + D S
Sbjct: 678 DELVTQRR---KHASSIKDLTKQLQQARRKLDQVESGSYDKEVSSMGSRSSSSGSLNARS 734
Query: 523 QMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKE 582
+ E N + + A DN V + +R + L K +EK++ E
Sbjct: 735 SAEDRSPE--NTGSSV-------AVDNFPQVDKAMLIER--IVRLQKAHARKNEKIEFME 783
Query: 583 NEIKRLVESMTE-----QEHVLNKKEKEIKM-LNEKEEEHMNIINLLHNKLELRNEADID 636
+ IK+LVE + + Q ++L ++ + ++ + H++ + L + AD
Sbjct: 784 DHIKQLVEEIRKKTKIIQSYILREESGTLSSEASDFNKVHLSRRGGIMASLYTSHPADNG 843
Query: 637 VIITLA-KYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRTLRKNMSGL 683
+ + L+ + + L VLE + N LK +L + T+ L K+ L
Sbjct: 844 LTLELSLEINRKLLAVLEDTLLKNITLKENLQTLGTEIERLIKHQHEL 891
>BC126305-1|AAI26306.1| 1438|Homo sapiens CLIP1 protein protein.
Length = 1438
Score = 47.2 bits (107), Expect = 2e-04
Identities = 122/655 (18%), Positives = 254/655 (38%), Gaps = 66/655 (10%)
Query: 3 QEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVT-FEKSKK----ELED 57
Q E+E QNQ D E E++ ++ K+ K K E + + +K++ E+ED
Sbjct: 671 QHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMED 730
Query: 58 RQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALE 117
N++ E + +++++L K N + + + K + E+LL L AL
Sbjct: 731 TLNKLQEAEIKV----KELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDL------DALR 780
Query: 118 HSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTK--TLTMK 175
++ + K ++ KL + + + ++ + S+ + +G K L
Sbjct: 781 KASSEGK--SEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQEN 838
Query: 176 IKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLN-- 233
+ E + + L+ L L+ +F + + + R L + ++ + SDL
Sbjct: 839 LSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKL 898
Query: 234 TQN-AEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVER 292
+N A+M + D + +L++ +L+
Sbjct: 899 RENLADMEAKFREKDEREEQLIK-AKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERD 957
Query: 293 VVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALA 352
V +L+ L +A + L++++ E QE K + K +++
Sbjct: 958 VEELQLKLTKANENASFLQKSI----EDMTVKAEQSQQEAAKKHEEEK------KELERK 1007
Query: 353 REKLQSXXXXXXXXXXXXSASYNKSIKD--MKHEMNL-NIAK-LIEIEKKYNDSIEEKKT 408
L+ A Y ++ + KHE L N+ K L++ E K + EE
Sbjct: 1008 LSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSG 1067
Query: 409 LQENIDDLR--TDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIE 466
L + +++LR D ++ +D ++ + E + + K LE TK + E++
Sbjct: 1068 LLQELEELRKQADKAKAAQTAEDAMQIM---EQMTKEKTETLASLEDTKQTNAKLQNELD 1124
Query: 467 EYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKS 526
K + EE+++ K L+ E + + Q+ +
Sbjct: 1125 TLKENNLKNVEELNKSKELLTVENQKME----------EFRKEIETLKQAAAQKSQQLSA 1174
Query: 527 YYEELMNLKNQITQLR-EFGAFDNLNDVGNMINQQRDKLFELTKRQEEY----DEKLQTK 581
EE + L ++ + R E + L + +++N Q L E+ KR+ ++ DE+ +
Sbjct: 1175 LQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQ---LLEMKKRESKFIKDADEEKASL 1231
Query: 582 ENEIKRLVESMTEQEHVLNKKEKEIKML---NEKEEEHMNIINLLHN---KLELR 630
+ I +TE++ L K E+ +L N + +++ L + KLEL+
Sbjct: 1232 QKSISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELK 1286
Score = 43.6 bits (98), Expect = 0.002
Identities = 56/231 (24%), Positives = 101/231 (43%), Gaps = 19/231 (8%)
Query: 409 LQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEY 468
L+ +D LRT + ++ +L+ +L+E++ +E Q +E TK DLE +K++I E
Sbjct: 406 LEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLE-QKSQISED 464
Query: 469 KRLLFEKGE--EIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKS 526
K E I EL+ L EK D E +
Sbjct: 465 PENTQTKLEHARIKELEQSLLFEKTKAD---KLQRELEDTRVATVSEKSRIMELEKDLAL 521
Query: 527 YYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKL--------FELTKRQEEYDEKL 578
+E+ L+ ++ + G D + I+ ++KL E+T +E + +
Sbjct: 522 RVQEVAELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGARE 581
Query: 579 QTKENEIKRLVESMTEQEHVLNKKEKEIK-MLNEKEEEHMNIINLLHNKLE 628
+T + EIK L + TE+ L+K+ + +K L +E+ ++I L +KLE
Sbjct: 582 ETHQKEIKALY-TATEK---LSKENESLKSKLEHANKENSDVIALWKSKLE 628
Score = 38.7 bits (86), Expect = 0.070
Identities = 26/103 (25%), Positives = 54/103 (52%), Gaps = 5/103 (4%)
Query: 393 IEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELE 452
+E E +E+K + E+ ++ +T L R+K+L + L +++ + +Q+ELE
Sbjct: 445 VEEESITKGDLEQKSQISEDPENTQTKL--EHARIKELEQSLLFEKTKADK---LQRELE 499
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDI 495
T+ K+ I E ++ L + +E+ EL+ +L + K D+
Sbjct: 500 DTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDV 542
>BC105632-1|AAI05633.1| 898|Homo sapiens chromosome 10 open reading
frame 118 protein.
Length = 898
Score = 47.2 bits (107), Expect = 2e-04
Identities = 64/320 (20%), Positives = 132/320 (41%), Gaps = 29/320 (9%)
Query: 375 NKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVREL 434
NK ++ + E + K + EK+ D +EK+TL++ + D +L ++ ++K L +E
Sbjct: 298 NKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKNTNKIKQLSQEK 357
Query: 435 DEKESILETKQ----CVQKELESTKTDLEHRKTEIE----EYKRLLFEKGEEIDELK--- 483
+ ETK+ + +E++ K D+ +++ + K + E D+LK
Sbjct: 358 GRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKETKDKLKETT 417
Query: 484 SKLSTEKAIKD---------IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNL 534
+KL+ K D I E QM+ ++L
Sbjct: 418 TKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMH 477
Query: 535 KNQITQLREF-----GAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRL- 588
+I +L + D L + + D+ +Y E + ++ EI+ L
Sbjct: 478 HAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLL 537
Query: 589 --VESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVII-TLAKYK 645
V++ + + L + ++EI+ L E+ E ++IN L +E + + ++++ T
Sbjct: 538 DKVKTADQLQEQLQRGKQEIENLKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTS 597
Query: 646 KSLTLVLEKMSISNRVLKCS 665
K+ L E S+ ++ K S
Sbjct: 598 KNAQLQSESNSLQSQFDKVS 617
Score = 44.4 bits (100), Expect = 0.001
Identities = 57/288 (19%), Positives = 123/288 (42%), Gaps = 17/288 (5%)
Query: 375 NKSIKDMKHEMNL-NIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRE 433
NK +K + ++ ++ +++ + + + + + ++ R E E V VR
Sbjct: 262 NKEVKASRDQLIAQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQ---EKEAMVMKYVRG 318
Query: 434 LDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGE--EIDELKSKLSTEKA 491
E + + K+ ++K+L +LE +I K+L EKG ++ E K T +
Sbjct: 319 EKESLDLRKEKETLEKKLRDANKELEKNTNKI---KQLSQEKGRLHQLYETKEG-ETTRL 374
Query: 492 IKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLN 551
I++I +S K ++L ++TQ +E A
Sbjct: 375 IREIDKLKEDINSHVIKVKWAQNKLKAEMDSH-KETKDKLKETTTKLTQAKE-EADQIRK 432
Query: 552 DVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNE 611
+ +MI ++ E+ + E D KL+ + E+++ ++ ++Q + + K KE++ L
Sbjct: 433 NCQDMIKTYQESE-EI--KSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKR 489
Query: 612 KEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISN 659
+E M+ + L K++ + + L+KYK+ + +K I N
Sbjct: 490 TFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIIN--RQKAEIQN 535
Score = 42.7 bits (96), Expect = 0.004
Identities = 128/708 (18%), Positives = 272/708 (38%), Gaps = 61/708 (8%)
Query: 8 IQQNQTDGCLYEDL-NEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELY 66
I++N+ L+ D+ +E++++ E K T+ + ++ M T ++ + +E+ +V
Sbjct: 213 IKENKKHQELFVDICSEKDNLREELKKRTETE---KQHMNTIKQLESRIEELNKEVKASR 269
Query: 67 ASLRNTHRKMKLLGQKVNLPSAEELHIMNV----AKLSPEQLLQLCAGGEPKAL----EH 118
L K Q+++ A+ + N A+ E ++ GE ++L E
Sbjct: 270 DQLIAQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEK 329
Query: 119 STLDNKVTFDVNKLLNIPNSLVDKCEET------LFKRKE--IINWFESLMSQEKGISTK 170
TL+ K+ D NK L + + + + L++ KE + ++ I++
Sbjct: 330 ETLEKKLR-DANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSH 388
Query: 171 TLTMKIKE--FNAENDLLKSSLDQLR--TEFLKEINDIIDCLRKNANETMALQLRTKELS 226
+ +K + AE D K + D+L+ T L + + D +RKN + + ++E+
Sbjct: 389 VIKVKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIK 448
Query: 227 CALSD--LNTQNAEMRKQIH--SGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRA 282
D L E+ KQ+ S +A ++ ++
Sbjct: 449 SNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCL 508
Query: 283 EHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDN 342
E + + + + + + + ++E +L V QE+ L + ++
Sbjct: 509 EDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRG-KQEIENLKEEVESL 567
Query: 343 TTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDS 402
+ + D+ E + + S N ++ + + K+ E +
Sbjct: 568 NSLINDLQKDIEGSRKRESELLLFTERLT-SKNAQLQSESNSLQSQFDKVSCSESQLQSQ 626
Query: 403 IEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRK 462
E+ K Q NI+ LES L ++ +R+ +E +++ C Q E+++ T +E K
Sbjct: 627 CEQMK--QTNIN------LESRLLKEEELRK-EEVQTLQAELACRQTEVKALSTQVEELK 677
Query: 463 TEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRES 522
E+ +R + I +L +L + D S
Sbjct: 678 DELVTQRR---KHASSIKDLTKQLQQARRKLDQVESGSYDKEVSSMGSRSSSSGSLNARS 734
Query: 523 QMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKE 582
+ E N + + A DN V + +R + L K +EK++ E
Sbjct: 735 SAEDRSPE--NTGSSV-------AVDNFPQVDKAMLIER--IVRLQKAHARKNEKIEFME 783
Query: 583 NEIKRLVESMTE-----QEHVLNKKEKEIKM-LNEKEEEHMNIINLLHNKLELRNEADID 636
+ IK+LVE + + Q ++L ++ + ++ + H++ + L + AD
Sbjct: 784 DHIKQLVEEIRKKTKIIQSYILREESGTLSSEASDFNKVHLSRRGGIMASLYTSHPADNG 843
Query: 637 VIITLA-KYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRTLRKNMSGL 683
+ + L+ + + L VLE + N LK +L + T+ L K+ L
Sbjct: 844 LTLELSLEINRKLQAVLEDTLLKNITLKENLQTLGTEIERLIKHQHEL 891
>BC103499-1|AAI03500.1| 898|Homo sapiens chromosome 10 open reading
frame 118 protein.
Length = 898
Score = 47.2 bits (107), Expect = 2e-04
Identities = 64/320 (20%), Positives = 132/320 (41%), Gaps = 29/320 (9%)
Query: 375 NKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVREL 434
NK ++ + E + K + EK+ D +EK+TL++ + D +L ++ ++K L +E
Sbjct: 298 NKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKNTNKIKQLSQEK 357
Query: 435 DEKESILETKQ----CVQKELESTKTDLEHRKTEIE----EYKRLLFEKGEEIDELK--- 483
+ ETK+ + +E++ K D+ +++ + K + E D+LK
Sbjct: 358 GRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKETKDKLKETT 417
Query: 484 SKLSTEKAIKD---------IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNL 534
+KL+ K D I E QM+ ++L
Sbjct: 418 TKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMH 477
Query: 535 KNQITQLREF-----GAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRL- 588
+I +L + D L + + D+ +Y E + ++ EI+ L
Sbjct: 478 HAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLL 537
Query: 589 --VESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVII-TLAKYK 645
V++ + + L + ++EI+ L E+ E ++IN L +E + + ++++ T
Sbjct: 538 DKVKTADQLQEQLQRGKQEIENLKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTS 597
Query: 646 KSLTLVLEKMSISNRVLKCS 665
K+ L E S+ ++ K S
Sbjct: 598 KNAQLQSESNSLQSQFDKVS 617
Score = 42.7 bits (96), Expect = 0.004
Identities = 128/708 (18%), Positives = 272/708 (38%), Gaps = 61/708 (8%)
Query: 8 IQQNQTDGCLYEDL-NEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELY 66
I++N+ L+ D+ +E++++ E K T+ + ++ M T ++ + +E+ +V
Sbjct: 213 IKENKKHQELFVDICSEKDNLREELKKRTETE---KQHMNTIKQLESRIEELNKEVKASR 269
Query: 67 ASLRNTHRKMKLLGQKVNLPSAEELHIMNV----AKLSPEQLLQLCAGGEPKAL----EH 118
L K Q+++ A+ + N A+ E ++ GE ++L E
Sbjct: 270 DKLIAQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEK 329
Query: 119 STLDNKVTFDVNKLLNIPNSLVDKCEET------LFKRKE--IINWFESLMSQEKGISTK 170
TL+ K+ D NK L + + + + L++ KE + ++ I++
Sbjct: 330 ETLEKKLR-DANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSH 388
Query: 171 TLTMKIKE--FNAENDLLKSSLDQLR--TEFLKEINDIIDCLRKNANETMALQLRTKELS 226
+ +K + AE D K + D+L+ T L + + D +RKN + + ++E+
Sbjct: 389 VIKVKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIK 448
Query: 227 CALSD--LNTQNAEMRKQIH--SGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRA 282
D L E+ KQ+ S +A ++ ++
Sbjct: 449 SNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCL 508
Query: 283 EHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDN 342
E + + + + + + + ++E +L V QE+ L + ++
Sbjct: 509 EDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRG-KQEIENLKEEVESL 567
Query: 343 TTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDS 402
+ + D+ E + + S N ++ + + K+ E +
Sbjct: 568 NSLINDLQKDIEGSRKRESELLLFTERLT-SKNAQLQSESNSLQSQFDKVSCSESQLQSQ 626
Query: 403 IEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRK 462
E+ K Q NI+ LES L ++ +R+ +E +++ C Q E+++ T +E K
Sbjct: 627 CEQMK--QTNIN------LESRLLKEEELRK-EEVQTLQAELACRQTEVKALSTQVEELK 677
Query: 463 TEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRES 522
E+ +R + I +L +L + D S
Sbjct: 678 DELVTQRR---KHASSIKDLTKQLQQARRKLDQVESGSYDKEVSSMGSRSSSSGSLNARS 734
Query: 523 QMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKE 582
+ E N + + A DN V + +R + L K +EK++ E
Sbjct: 735 SAEDRSPE--NTGSSV-------AVDNFPQVDKAMLIER--IVRLQKAHARKNEKIEFME 783
Query: 583 NEIKRLVESMTE-----QEHVLNKKEKEIKM-LNEKEEEHMNIINLLHNKLELRNEADID 636
+ IK+LVE + + Q ++L ++ + ++ + H++ + L + AD
Sbjct: 784 DHIKQLVEEIRKKTKIIQSYILREESGTLSSEASDFNKVHLSRRGGIMASLYTSHPADNG 843
Query: 637 VIITLA-KYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRTLRKNMSGL 683
+ + L+ + + L VLE + N LK +L + T+ L K+ L
Sbjct: 844 LTLELSLEINRKLQAVLEDTLLKNITLKENLQTLGTEIERLIKHQHEL 891
>BC100670-1|AAI00671.1| 1004|Homo sapiens C10orf118 protein protein.
Length = 1004
Score = 47.2 bits (107), Expect = 2e-04
Identities = 64/320 (20%), Positives = 132/320 (41%), Gaps = 29/320 (9%)
Query: 375 NKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVREL 434
NK ++ + E + K + EK+ D +EK+TL++ + D +L ++ ++K L +E
Sbjct: 404 NKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKNTNKIKQLSQEK 463
Query: 435 DEKESILETKQ----CVQKELESTKTDLEHRKTEIE----EYKRLLFEKGEEIDELK--- 483
+ ETK+ + +E++ K D+ +++ + K + E D+LK
Sbjct: 464 GRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKETKDKLKETT 523
Query: 484 SKLSTEKAIKD---------IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNL 534
+KL+ K D I E QM+ ++L
Sbjct: 524 TKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMH 583
Query: 535 KNQITQLREF-----GAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRL- 588
+I +L + D L + + D+ +Y E + ++ EI+ L
Sbjct: 584 HAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLL 643
Query: 589 --VESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVII-TLAKYK 645
V++ + + L + ++EI+ L E+ E ++IN L +E + + ++++ T
Sbjct: 644 DKVKTADQLQEQLQRGKQEIENLKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTS 703
Query: 646 KSLTLVLEKMSISNRVLKCS 665
K+ L E S+ ++ K S
Sbjct: 704 KNAQLQSESNSLQSQFDKVS 723
Score = 44.4 bits (100), Expect = 0.001
Identities = 57/288 (19%), Positives = 123/288 (42%), Gaps = 17/288 (5%)
Query: 375 NKSIKDMKHEMNL-NIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRE 433
NK +K + ++ ++ +++ + + + + + ++ R E E V VR
Sbjct: 368 NKEVKASRDQLIAQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQ---EKEAMVMKYVRG 424
Query: 434 LDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGE--EIDELKSKLSTEKA 491
E + + K+ ++K+L +LE +I K+L EKG ++ E K T +
Sbjct: 425 EKESLDLRKEKETLEKKLRDANKELEKNTNKI---KQLSQEKGRLHQLYETKEG-ETTRL 480
Query: 492 IKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLN 551
I++I +S K ++L ++TQ +E A
Sbjct: 481 IREIDKLKEDINSHVIKVKWAQNKLKAEMDSH-KETKDKLKETTTKLTQAKE-EADQIRK 538
Query: 552 DVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNE 611
+ +MI ++ E+ + E D KL+ + E+++ ++ ++Q + + K KE++ L
Sbjct: 539 NCQDMIKTYQESE-EI--KSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKR 595
Query: 612 KEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISN 659
+E M+ + L K++ + + L+KYK+ + +K I N
Sbjct: 596 TFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIIN--RQKAEIQN 641
Score = 42.7 bits (96), Expect = 0.004
Identities = 128/708 (18%), Positives = 272/708 (38%), Gaps = 61/708 (8%)
Query: 8 IQQNQTDGCLYEDL-NEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELY 66
I++N+ L+ D+ +E++++ E K T+ + ++ M T ++ + +E+ +V
Sbjct: 319 IKENKKHQELFVDICSEKDNLREELKKRTETE---KQHMNTIKQLESRIEELNKEVKASR 375
Query: 67 ASLRNTHRKMKLLGQKVNLPSAEELHIMNV----AKLSPEQLLQLCAGGEPKAL----EH 118
L K Q+++ A+ + N A+ E ++ GE ++L E
Sbjct: 376 DQLIAQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEK 435
Query: 119 STLDNKVTFDVNKLLNIPNSLVDKCEET------LFKRKE--IINWFESLMSQEKGISTK 170
TL+ K+ D NK L + + + + L++ KE + ++ I++
Sbjct: 436 ETLEKKLR-DANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSH 494
Query: 171 TLTMKIKE--FNAENDLLKSSLDQLR--TEFLKEINDIIDCLRKNANETMALQLRTKELS 226
+ +K + AE D K + D+L+ T L + + D +RKN + + ++E+
Sbjct: 495 VIKVKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIK 554
Query: 227 CALSD--LNTQNAEMRKQIH--SGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRA 282
D L E+ KQ+ S +A ++ ++
Sbjct: 555 SNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCL 614
Query: 283 EHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDN 342
E + + + + + + + ++E +L V QE+ L + ++
Sbjct: 615 EDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRG-KQEIENLKEEVESL 673
Query: 343 TTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDS 402
+ + D+ E + + S N ++ + + K+ E +
Sbjct: 674 NSLINDLQKDIEGSRKRESELLLFTERLT-SKNAQLQSESNSLQSQFDKVSCSESQLQSQ 732
Query: 403 IEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRK 462
E+ K Q NI+ LES L ++ +R+ +E +++ C Q E+++ T +E K
Sbjct: 733 CEQMK--QTNIN------LESRLLKEEELRK-EEVQTLQAELACRQTEVKALSTQVEELK 783
Query: 463 TEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRES 522
E+ +R + I +L +L + D S
Sbjct: 784 DELVTQRR---KHASSIKDLTKQLQQARRKLDQVESGSYDKEVSSMGSRSSSSGSLNARS 840
Query: 523 QMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKE 582
+ E N + + A DN V + +R + L K +EK++ E
Sbjct: 841 SAEDRSPE--NTGSSV-------AVDNFPQVDKAMLIER--IVRLQKAHARKNEKIEFME 889
Query: 583 NEIKRLVESMTE-----QEHVLNKKEKEIKM-LNEKEEEHMNIINLLHNKLELRNEADID 636
+ IK+LVE + + Q ++L ++ + ++ + H++ + L + AD
Sbjct: 890 DHIKQLVEEIRKKTKIIQSYILREESGTLSSEASDFNKVHLSRRGGIMASLYTSHPADNG 949
Query: 637 VIITLA-KYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRTLRKNMSGL 683
+ + L+ + + L VLE + N LK +L + T+ L K+ L
Sbjct: 950 LTLELSLEINRKLQAVLEDTLLKNITLKENLQTLGTEIERLIKHQHEL 997
>AF450487-1|AAP97680.1| 1662|Homo sapiens kinesin-like protein KIF2
protein.
Length = 1662
Score = 47.2 bits (107), Expect = 2e-04
Identities = 48/195 (24%), Positives = 85/195 (43%), Gaps = 12/195 (6%)
Query: 429 DLVRELDEKESILETKQCVQKELESTKTDLEHR-KTEIEEYKRLLFEKGEEIDELKSKLS 487
D +E E++ + E ++ + E+E ++ +H + E EE + + GE DE S+ S
Sbjct: 568 DTDQEKKEEKGVSE-RETQELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSE-S 625
Query: 488 TEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEE-LMNLKNQI--TQLREF 544
EKA R +K YEE LM L+++I TQL
Sbjct: 626 DEKANYQADLANITCDIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERD 685
Query: 545 GAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEK 604
NL V + ++ K+ + EY++KLQ E++RL + E +L + +
Sbjct: 686 QVLQNLGSVESYSEEKAKKV------RSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQ 739
Query: 605 EIKMLNEKEEEHMNI 619
K L + +++ M +
Sbjct: 740 YEKQLKKLQQDVMEM 754
>AF273054-1|AAM44457.1| 613|Homo sapiens CTCL tumor antigen
HD-CL-01 protein.
Length = 613
Score = 47.2 bits (107), Expect = 2e-04
Identities = 64/320 (20%), Positives = 132/320 (41%), Gaps = 29/320 (9%)
Query: 375 NKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVREL 434
NK ++ + E + K + EK+ D +EK+TL++ + D +L ++ ++K L +E
Sbjct: 115 NKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKNTNKIKQLSQEK 174
Query: 435 DEKESILETKQ----CVQKELESTKTDLEHRKTEIE----EYKRLLFEKGEEIDELK--- 483
+ ETK+ + +E++ K D+ +++ + K + E D+LK
Sbjct: 175 GRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKETKDKLKETT 234
Query: 484 SKLSTEKAIKD---------IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNL 534
+KL+ K D I E QM+ ++L
Sbjct: 235 TKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMH 294
Query: 535 KNQITQLREF-----GAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRL- 588
+I +L + D L + + D+ +Y E + ++ EI+ L
Sbjct: 295 HAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLL 354
Query: 589 --VESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVII-TLAKYK 645
V++ + + L + ++EI+ L E+ E ++IN L +E + + ++++ T
Sbjct: 355 DKVKTADQLQEQLQRGKQEIENLKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTS 414
Query: 646 KSLTLVLEKMSISNRVLKCS 665
K+ L E S+ ++ K S
Sbjct: 415 KNAQLQSESNSLQSQFDKVS 434
>DQ109808-1|AAZ83370.1| 2479|Homo sapiens nephrocystin-6 protein.
Length = 2479
Score = 46.8 bits (106), Expect = 3e-04
Identities = 55/250 (22%), Positives = 108/250 (43%), Gaps = 24/250 (9%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKE 450
++ E++ K ++I K LQEN +D ++ + + V+DL LD+ + + QC++ E
Sbjct: 1656 EITELKVKEFENI--KLQLQENHED---EVKKVKAEVEDLKYLLDQSQ---KESQCLKSE 1707
Query: 451 LESTKTDLEHRKTE-----IEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXX 505
L++ K T +E K L K ++ L L +A
Sbjct: 1708 LQAQKEANSRAPTTTMRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISAT 1767
Query: 506 XXXXXXXXXXXXXXR-----ESQMKSYYEELMNLKNQI--TQLREFGAFDNLNDVGNMIN 558
R ++Q++ E L+ LK + ++ RE DNLND+ N +
Sbjct: 1768 SQKEAHLNVQQIVDRHTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQ 1827
Query: 559 QQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMN 618
+++ ++ + +EE D++ + +IKRL + + NK+ ++ E + +
Sbjct: 1828 KKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQGKPLTDNKQ----SLIEELQRKVKK 1883
Query: 619 IINLLHNKLE 628
+ N L K+E
Sbjct: 1884 LENQLEGKVE 1893
Score = 44.4 bits (100), Expect = 0.001
Identities = 69/389 (17%), Positives = 158/389 (40%), Gaps = 34/389 (8%)
Query: 280 SRAEHQLKTNVERVVQLEAALEQARSESWSLE-RTVXXXXXXXXXXXEDFDQELNKLTQS 338
++ E+QLKT +V++LE LE A+ + + R + E D+EL + +
Sbjct: 81 AKFENQLKT---KVMKLENELEMAQQSAGGRDTRFLRNEICQLEKQLEQKDRELEDMEKE 137
Query: 339 IKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKK 398
++ E +AL E+ ++ NK +K ++ +I I+ +K+
Sbjct: 138 LEKEKKVNEQLALRNEEAENENSKLRRE--------NKRLKKKNEQLCQDI---IDYQKQ 186
Query: 399 YNDSIEEKKTLQENIDDLRTDLLESE---LRVKDLVRELDEKESILETK-QCVQKELEST 454
+ E + + D R+ L + ++ D ++ L E +E + Q ++K LE +
Sbjct: 187 IDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEES 246
Query: 455 KTDLEHRKTEIEEYKRLLFEKGEEIDELKSK-----LSTEKA---IKDIXXXXXXXXXXX 506
++E E K ++ + ID+LK + L ++ +K
Sbjct: 247 VQEMEKMTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQELTDLLKSKNEEDDPIMVAV 306
Query: 507 XXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFE 566
++ ++ Y + L NL+ ++ + N+ + I ++ ++
Sbjct: 307 NAKVEEWKLILSSKDDEIIEYQQMLHNLREKLKNAQLDADKSNVMALQQGIQERDSQIKM 366
Query: 567 LTKRQEEYDEKLQTK-------ENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNI 619
LT++ E+Y ++++ +NE++R + T + K + + +L EK +E
Sbjct: 367 LTEQVEQYTKEMEKNTCIIEDLKNELQRNKGASTLSQQTHMKIQSTLDILKEKTKEAERT 426
Query: 620 INLLHNKLELRNEADIDVIITLAKYKKSL 648
L +++ ++ + L Y+ +
Sbjct: 427 AELAEADAREKDKELVEALKRLKDYESGV 455
Score = 35.5 bits (78), Expect = 0.65
Identities = 46/222 (20%), Positives = 92/222 (41%), Gaps = 13/222 (5%)
Query: 420 LLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI 479
+LE+ K L +L EKES L + + +L R E ++L+ E G +
Sbjct: 1467 ILETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPATAEREKLIAELGRKE 1526
Query: 480 DELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQ---MKSYYEELMNLKN 536
E KS + + A + I RE Q +K + E+L L +
Sbjct: 1527 MEPKSHHTLKIAHQTIANMQARLNQKEEVLKKYQRLLEKAREEQREIVKKHEEDLHILHH 1586
Query: 537 QI-----TQLREF--GAFDNLNDVGNMI--NQQRDKLFELTKRQEEYDEKLQTKENEIKR 587
++ + L +F A+D + + N+ +L E+ + E D+ L + ++K+
Sbjct: 1587 RLELQADSSLNKFKQTAWDLMKQSPTPVPTNKHFIRLAEMEQTVAEQDDSLSSLLVKLKK 1646
Query: 588 LVESMTEQEHVLNKKEKEIKMLN-EKEEEHMNIINLLHNKLE 628
+ + + Q + K KE + + + +E H + + + ++E
Sbjct: 1647 VSQDLERQREITELKVKEFENIKLQLQENHEDEVKKVKAEVE 1688
Score = 33.9 bits (74), Expect = 2.0
Identities = 33/132 (25%), Positives = 62/132 (46%), Gaps = 15/132 (11%)
Query: 374 YNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRE 433
+ + +K ++N N+ KL E K S + +L +N++DL +L + + ++RE
Sbjct: 1783 HTRELKTQVEDLNENLLKLKEALKT---SKNRENSLTDNLNDLNNELQKKQKAYNKILRE 1839
Query: 434 LDE--------KESILETKQCVQ-KELESTKTDL-EHRKTEIEEYKRLLFEKGEEID--E 481
+E K I +Q K L K L E + ++++ + L K EE+D
Sbjct: 1840 KEEIDQENDELKRQIKRLTSGLQGKPLTDNKQSLIEELQRKVKKLENQLEGKVEEVDLKP 1899
Query: 482 LKSKLSTEKAIK 493
+K K + E+ I+
Sbjct: 1900 MKEKNAKEELIR 1911
Score = 33.1 bits (72), Expect = 3.5
Identities = 57/312 (18%), Positives = 126/312 (40%), Gaps = 22/312 (7%)
Query: 326 EDFDQELNKLTQSIKDNTTHLE-DIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHE 384
E +E K +K LE ++ +A+ QS K ++ E
Sbjct: 74 EKAGEEQAKFENQLKTKVMKLENELEMAQ---QSAGGRDTRFLRNEICQLEKQLEQKDRE 130
Query: 385 MNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETK 444
+ ++ K +E EKK N+ + + EN + S+LR ++ R + E + +
Sbjct: 131 LE-DMEKELEKEKKVNEQLALRNEEAENEN--------SKLR-RENKRLKKKNEQLCQDI 180
Query: 445 QCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXX 504
QK+++S K L R+ E +Y+ L +K E+ + ++ T +
Sbjct: 181 IDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMR 240
Query: 505 XXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAF--DNLNDVGNMINQQRD 562
++MK+ + N+ +Q+ + + L D+ N++ D
Sbjct: 241 KNLEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQELTDLLKSKNEEDD 300
Query: 563 KLF-ELTKRQEEYDEKLQTKENEI---KRLVESMTE--QEHVLNKKEKEIKMLNEKEEEH 616
+ + + EE+ L +K++EI ++++ ++ E + L+ + + L + +E
Sbjct: 301 PIMVAVNAKVEEWKLILSSKDDEIIEYQQMLHNLREKLKNAQLDADKSNVMALQQGIQER 360
Query: 617 MNIINLLHNKLE 628
+ I +L ++E
Sbjct: 361 DSQIKMLTEQVE 372
Score = 31.9 bits (69), Expect = 8.0
Identities = 20/84 (23%), Positives = 46/84 (54%), Gaps = 7/84 (8%)
Query: 560 QRDKLF-ELTKRQEE--YDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEE- 615
+R+KL EL +++ E L+ I + + ++E VL K ++ ++ E++ E
Sbjct: 1514 EREKLIAELGRKEMEPKSHHTLKIAHQTIANMQARLNQKEEVLKKYQRLLEKAREEQREI 1573
Query: 616 ---HMNIINLLHNKLELRNEADID 636
H +++LH++LEL+ ++ ++
Sbjct: 1574 VKKHEEDLHILHHRLELQADSSLN 1597
>BX284668-3|CAH70057.1| 1898|Homo sapiens ciliary rootlet
coiled-coil, rootletin protein.
Length = 1898
Score = 46.8 bits (106), Expect = 3e-04
Identities = 52/259 (20%), Positives = 113/259 (43%), Gaps = 20/259 (7%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSI-EEKKTLQENIDDLRTDLLESELRVKDLVREL 434
+S ++ N+A +++ ++ + + +E++ LQ ++LR R +D + E
Sbjct: 476 RSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELR--------RQRDRLEE- 526
Query: 435 DEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKD 494
E+E ++ V++ELE + HR+ E E KR + K E+ E++ LS +D
Sbjct: 527 -EQEDAVQDGARVRRELERS-----HRQLEQLEGKRSVLAK--ELVEVREALSRATLQRD 578
Query: 495 IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVG 554
+ +++++ L + ++++ L E A D L D+
Sbjct: 579 MLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKL-DLN 637
Query: 555 NMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEE 614
++ Q ++ L RQ + +++ E +RL E EQE E +++ + +E
Sbjct: 638 RLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQE 697
Query: 615 E-HMNIINLLHNKLELRNE 632
+ L H + +L+ +
Sbjct: 698 ALEQQLPTLRHERSQLQEQ 716
Score = 32.7 bits (71), Expect = 4.6
Identities = 23/96 (23%), Positives = 47/96 (48%), Gaps = 3/96 (3%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKE 450
+L+E ++K +S E ++ ++ +LR L E + L R +E S ++ + +
Sbjct: 1057 ELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERIS 1116
Query: 451 LESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKL 486
L+ D E + +EE + + G+E EL++ L
Sbjct: 1117 LKLANEDKEQKLALLEEARTAV---GKEAGELRTGL 1149
Score = 31.9 bits (69), Expect = 8.0
Identities = 26/120 (21%), Positives = 55/120 (45%), Gaps = 4/120 (3%)
Query: 378 IKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRV-KDLVRELDE 436
++DM+ + L + K+ +DS E++ L+E + LR D + ++ +D RE+
Sbjct: 416 VQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLR-DKTDGAMQAHEDAQREVQR 474
Query: 437 KESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEK--AIKD 494
S E + L + + + E+ + + L EE+ + +L E+ A++D
Sbjct: 475 LRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQD 534
>BX284668-2|CAH70055.1| 2017|Homo sapiens ciliary rootlet
coiled-coil, rootletin protein.
Length = 2017
Score = 46.8 bits (106), Expect = 3e-04
Identities = 52/259 (20%), Positives = 113/259 (43%), Gaps = 20/259 (7%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSI-EEKKTLQENIDDLRTDLLESELRVKDLVREL 434
+S ++ N+A +++ ++ + + +E++ LQ ++LR R +D + E
Sbjct: 595 RSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELR--------RQRDRLEE- 645
Query: 435 DEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKD 494
E+E ++ V++ELE + HR+ E E KR + K E+ E++ LS +D
Sbjct: 646 -EQEDAVQDGARVRRELERS-----HRQLEQLEGKRSVLAK--ELVEVREALSRATLQRD 697
Query: 495 IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVG 554
+ +++++ L + ++++ L E A D L D+
Sbjct: 698 MLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKL-DLN 756
Query: 555 NMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEE 614
++ Q ++ L RQ + +++ E +RL E EQE E +++ + +E
Sbjct: 757 RLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQE 816
Query: 615 E-HMNIINLLHNKLELRNE 632
+ L H + +L+ +
Sbjct: 817 ALEQQLPTLRHERSQLQEQ 835
Score = 32.7 bits (71), Expect = 4.6
Identities = 23/96 (23%), Positives = 47/96 (48%), Gaps = 3/96 (3%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKE 450
+L+E ++K +S E ++ ++ +LR L E + L R +E S ++ + +
Sbjct: 1176 ELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERIS 1235
Query: 451 LESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKL 486
L+ D E + +EE + + G+E EL++ L
Sbjct: 1236 LKLANEDKEQKLALLEEARTAV---GKEAGELRTGL 1268
Score = 31.9 bits (69), Expect = 8.0
Identities = 26/120 (21%), Positives = 55/120 (45%), Gaps = 4/120 (3%)
Query: 378 IKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRV-KDLVRELDE 436
++DM+ + L + K+ +DS E++ L+E + LR D + ++ +D RE+
Sbjct: 535 VQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLR-DKTDGAMQAHEDAQREVQR 593
Query: 437 KESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEK--AIKD 494
S E + L + + + E+ + + L EE+ + +L E+ A++D
Sbjct: 594 LRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQD 653
>BC126912-1|AAI26913.1| 1132|Homo sapiens CROCC protein protein.
Length = 1132
Score = 46.8 bits (106), Expect = 3e-04
Identities = 52/259 (20%), Positives = 113/259 (43%), Gaps = 20/259 (7%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSI-EEKKTLQENIDDLRTDLLESELRVKDLVREL 434
+S ++ N+A +++ ++ + + +E++ LQ ++LR R +D + E
Sbjct: 458 RSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELR--------RQRDRLEE- 508
Query: 435 DEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKD 494
E+E ++ V++ELE + HR+ E E KR + K E+ E++ LS +D
Sbjct: 509 -EQEDAVQDGARVRRELERS-----HRQLEQLEGKRSVLAK--ELVEVREALSRATLQRD 560
Query: 495 IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVG 554
+ +++++ L + ++++ L E A D L D+
Sbjct: 561 MLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKL-DLN 619
Query: 555 NMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEE 614
++ Q ++ L RQ + +++ E +RL E EQE E +++ + +E
Sbjct: 620 RLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQE 679
Query: 615 E-HMNIINLLHNKLELRNE 632
+ L H + +L+ +
Sbjct: 680 ALEQQLPTLRHERSQLQEQ 698
Score = 33.5 bits (73), Expect = 2.6
Identities = 20/88 (22%), Positives = 43/88 (48%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKE 450
+L+E ++K +S E ++ ++ +LR L E + L R +E S ++ + +
Sbjct: 1039 ELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERIS 1098
Query: 451 LESTKTDLEHRKTEIEEYKRLLFEKGEE 478
L+ D E + +EE + + + GE+
Sbjct: 1099 LKLANEDKEQKLALLEEARTAVGQPGED 1126
Score = 31.9 bits (69), Expect = 8.0
Identities = 26/120 (21%), Positives = 55/120 (45%), Gaps = 4/120 (3%)
Query: 378 IKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRV-KDLVRELDE 436
++DM+ + L + K+ +DS E++ L+E + LR D + ++ +D RE+
Sbjct: 398 VQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLR-DKTDGAMQAHEDAQREVQR 456
Query: 437 KESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEK--AIKD 494
S E + L + + + E+ + + L EE+ + +L E+ A++D
Sbjct: 457 LRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQD 516
>BC126911-1|AAI26912.1| 1132|Homo sapiens CROCC protein protein.
Length = 1132
Score = 46.8 bits (106), Expect = 3e-04
Identities = 52/259 (20%), Positives = 113/259 (43%), Gaps = 20/259 (7%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSI-EEKKTLQENIDDLRTDLLESELRVKDLVREL 434
+S ++ N+A +++ ++ + + +E++ LQ ++LR R +D + E
Sbjct: 458 RSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELR--------RQRDRLEE- 508
Query: 435 DEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKD 494
E+E ++ V++ELE + HR+ E E KR + K E+ E++ LS +D
Sbjct: 509 -EQEDAVQDGARVRRELERS-----HRQLEQLEGKRSVLAK--ELVEVREALSRATLQRD 560
Query: 495 IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVG 554
+ +++++ L + ++++ L E A D L D+
Sbjct: 561 MLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKL-DLN 619
Query: 555 NMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEE 614
++ Q ++ L RQ + +++ E +RL E EQE E +++ + +E
Sbjct: 620 RLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQE 679
Query: 615 E-HMNIINLLHNKLELRNE 632
+ L H + +L+ +
Sbjct: 680 ALEQQLPTLRHERSQLQEQ 698
Score = 33.5 bits (73), Expect = 2.6
Identities = 20/88 (22%), Positives = 43/88 (48%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKE 450
+L+E ++K +S E ++ ++ +LR L E + L R +E S ++ + +
Sbjct: 1039 ELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERIS 1098
Query: 451 LESTKTDLEHRKTEIEEYKRLLFEKGEE 478
L+ D E + +EE + + + GE+
Sbjct: 1099 LKLANEDKEQKLALLEEARTAVGQPGED 1126
Score = 31.9 bits (69), Expect = 8.0
Identities = 26/120 (21%), Positives = 55/120 (45%), Gaps = 4/120 (3%)
Query: 378 IKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRV-KDLVRELDE 436
++DM+ + L + K+ +DS E++ L+E + LR D + ++ +D RE+
Sbjct: 398 VQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLR-DKTDGAMQAHEDAQREVQR 456
Query: 437 KESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEK--AIKD 494
S E + L + + + E+ + + L EE+ + +L E+ A++D
Sbjct: 457 LRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQD 516
>BC117209-1|AAI17210.1| 1438|Homo sapiens CLIP1 protein protein.
Length = 1438
Score = 46.8 bits (106), Expect = 3e-04
Identities = 121/653 (18%), Positives = 249/653 (38%), Gaps = 62/653 (9%)
Query: 3 QEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVT-FEKSKK----ELED 57
Q E+E QNQ D E E++ ++ K+ K K E + + +K++ E+ED
Sbjct: 671 QHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMED 730
Query: 58 RQNQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALE 117
N++ E + +++++L K N + + + K + E+LL L AL
Sbjct: 731 TLNKLQEAEIKV----KELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDL------DALR 780
Query: 118 HSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTK--TLTMK 175
++ + K ++ KL + + + ++ + S+ + +G K L
Sbjct: 781 KASSEGK--SEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQEN 838
Query: 176 IKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLN-- 233
+ E + + L+ L L+ +F + + + R L + ++ + SDL
Sbjct: 839 LSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKL 898
Query: 234 TQN-AEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVER 292
+N A+M + D + +L++ +L+
Sbjct: 899 RENLADMEAKFREKDEREEQLIK-AKEKLENDIAEIMKMSGDNPSQLTKMNDELRLKERD 957
Query: 293 VVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALA 352
V +L+ L +A + L++++ E QE K + K +++
Sbjct: 958 VEELQLKLTKANENASFLQKSI----EDMTVKAEQSQQEAAKKHEEEK------KELERK 1007
Query: 353 REKLQSXXXXXXXXXXXXSASYNKSIKD--MKHEMNL-NIAK-LIEIEKKYNDSIEEKKT 408
L+ A Y ++ + KHE L N+ K L++ E K + EE
Sbjct: 1008 LSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSG 1067
Query: 409 LQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEY 468
L + +++LR E + + E + + K LE TK + E++
Sbjct: 1068 LLQELEELRKQ-AEKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTL 1126
Query: 469 KRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYY 528
K + EE+++ K L+ E + + Q+ +
Sbjct: 1127 KENNLKNVEELNKSKELLTVENQKME----------EFRKEIETLKQAAAQKSQQLSALQ 1176
Query: 529 EELMNLKNQITQLR-EFGAFDNLNDVGNMINQQRDKLFELTKRQEEY----DEKLQTKEN 583
EE + L ++ + R E + L + +++N Q L E+ KR+ ++ DE+ + +
Sbjct: 1177 EENVKLAEELGRSRDEVTSHQKLEEERSVLNNQ---LLEMKKRESKFIKDADEEKASLQK 1233
Query: 584 EIKRLVESMTEQEHVLNKKEKEIKML---NEKEEEHMNIINLLHN---KLELR 630
I +TE++ L K E+ +L N + +++ L + KLEL+
Sbjct: 1234 SISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELK 1286
Score = 43.6 bits (98), Expect = 0.002
Identities = 56/231 (24%), Positives = 101/231 (43%), Gaps = 19/231 (8%)
Query: 409 LQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEY 468
L+ +D LRT + ++ +L+ +L+E++ +E Q +E TK DLE +K++I E
Sbjct: 406 LEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLE-QKSQISED 464
Query: 469 KRLLFEKGE--EIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKS 526
K E I EL+ L EK D E +
Sbjct: 465 PENTQTKLEHARIKELEQSLLFEKTKAD---KLQRELEDTRVATVSEKSRIMELEKDLAL 521
Query: 527 YYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKL--------FELTKRQEEYDEKL 578
+E+ L+ ++ + G D + I+ ++KL E+T +E + +
Sbjct: 522 RVQEVAELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGARE 581
Query: 579 QTKENEIKRLVESMTEQEHVLNKKEKEIK-MLNEKEEEHMNIINLLHNKLE 628
+T + EIK L + TE+ L+K+ + +K L +E+ ++I L +KLE
Sbjct: 582 ETHQKEIKALY-TATEK---LSKENESLKSKLEHANKENSDVIALWKSKLE 628
Score = 38.7 bits (86), Expect = 0.070
Identities = 26/103 (25%), Positives = 54/103 (52%), Gaps = 5/103 (4%)
Query: 393 IEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELE 452
+E E +E+K + E+ ++ +T L R+K+L + L +++ + +Q+ELE
Sbjct: 445 VEEESITKGDLEQKSQISEDPENTQTKL--EHARIKELEQSLLFEKTKADK---LQRELE 499
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDI 495
T+ K+ I E ++ L + +E+ EL+ +L + K D+
Sbjct: 500 DTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDV 542
>AL832639-1|CAD89954.1| 1331|Homo sapiens hypothetical protein
protein.
Length = 1331
Score = 46.8 bits (106), Expect = 3e-04
Identities = 57/237 (24%), Positives = 102/237 (43%), Gaps = 21/237 (8%)
Query: 274 IMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXE---DFDQ 330
+M ++L E QL+ E + E + ++ LE E
Sbjct: 742 LMAEKLQLQE-QLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQA 800
Query: 331 ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIA 390
E K+ Q+I++ LE+ AR+KLQ + + D+ H+ +
Sbjct: 801 EKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEELDDLLVDLDHQRQ-SAC 859
Query: 391 KLIEIEKKYNDSIEEKKTLQENI----DDLRTDLLESELRVKDLVRELD---EKESILE- 442
L + +KK++ + E+KT+ D + E E + L R L+ E+++ LE
Sbjct: 860 NLEKKQKKFDQLLAEEKTISAKYAGERDRAEAEAREKETKALSLARALEEAMEQKAELER 919
Query: 443 -TKQ--CVQKELESTKTDLEHRKTEIEEYKRLLFEKGEE----IDELKSKL-STEKA 491
KQ ++L S+K D+ E+E+ KR L ++ EE ++EL+ +L +TE A
Sbjct: 920 LNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEGELQATEDA 976
Score = 40.7 bits (91), Expect = 0.017
Identities = 52/301 (17%), Positives = 122/301 (40%), Gaps = 21/301 (6%)
Query: 199 KEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXX 258
+E++D++ L L+ + K+ L++ T +A+ ++G+ R A
Sbjct: 842 EELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAK-----YAGERDRAEAEAREK 896
Query: 259 XXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXX 318
K L R Q +T +E ++ + + ++ E +R +
Sbjct: 897 ETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQV 956
Query: 319 XXXXXXXEDFDQELNKLTQSIKDNTTHLE-DIALAREKLQSXXXXXXXXXXXXSASYNKS 377
E+ + EL Q+ +D LE ++ + + + +
Sbjct: 957 EEMKTQLEELEGEL----QATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQ 1012
Query: 378 IKDMKHEM-------NLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDL 430
+++M+ E+ ++ +A ++E D + +N D+ L + + ++KD
Sbjct: 1013 VREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDC 1072
Query: 431 VRELDE----KESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKL 486
+RELD+ +E IL + +K+L+S + ++ + E+ +R + +E DEL ++
Sbjct: 1073 MRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEI 1132
Query: 487 S 487
+
Sbjct: 1133 A 1133
Score = 39.9 bits (89), Expect = 0.030
Identities = 51/245 (20%), Positives = 104/245 (42%), Gaps = 20/245 (8%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD 435
+ ++++ H++ A++ E E++ EKK +Q+NI +L L E E + L E
Sbjct: 775 QELEEICHDLE---ARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKV 831
Query: 436 EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDI 495
E+ L+ +++EL+ DL+H++ L +K ++ D+L L+ EK I
Sbjct: 832 TTEAKLKK---LEEELDDLLVDLDHQRQSACN----LEKKQKKFDQL---LAEEKTISAK 881
Query: 496 XXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQI-TQLREFGAFDNLNDVG 554
+ EL L Q T++ + + +DVG
Sbjct: 882 YAGERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDL--MSSKDDVG 939
Query: 555 NMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLN----KKEKEIKMLN 610
+++ L ++ EE +L+ E E++ ++ E L + E++++ +
Sbjct: 940 KSVHELEKSKRALEQQVEEMKTQLEELEGELQATEDAKLRLEVNLQAMKAQFERDLQGRD 999
Query: 611 EKEEE 615
E+ EE
Sbjct: 1000 EQSEE 1004
Score = 32.7 bits (71), Expect = 4.6
Identities = 91/517 (17%), Positives = 190/517 (36%), Gaps = 44/517 (8%)
Query: 1 MKQEELEIQQNQTDGCLYEDLNEQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQN 60
++ E+ ++QQN + L E L E+ES K+ K + K+ +K ++EL+D
Sbjct: 798 LQAEKKKMQQNIQE--LEEQLEEEESARQ---KLQLEKVTTEAKL---KKLEEELDDLLV 849
Query: 61 QVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHST 120
+ S N +K K Q + AEE I ++ E KAL +
Sbjct: 850 DLDHQRQSACNLEKKQKKFDQLL----AEEKTISAKYAGERDRAEAEAREKETKALSLAR 905
Query: 121 LDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFN 180
+ +L + + E+ + + ++ L ++ + + MK +
Sbjct: 906 ALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEE 965
Query: 181 AENDLLKSSLDQLRTEFLKEI------NDIIDCLRKNANETMALQLRTKELSCALSDLNT 234
E +L + +LR E + D+ ++ + L + +E+ L D
Sbjct: 966 LEGELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERK 1025
Query: 235 QNA---EMRKQIHSG----DHHRPYANRNXXXXXXXXXXXXXXXXSIMKD----RLSRAE 283
Q + RK++ + H AN+N M++ R SR E
Sbjct: 1026 QRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREE 1085
Query: 284 --HQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKD 341
Q K N +++ +EA + Q + E + ER ++ K ++++
Sbjct: 1086 ILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEE 1145
Query: 342 NTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYND 401
IA E+L+ + N I + ++NL + + E
Sbjct: 1146 KRRLEARIAQLEEELEEEQGNTELINDRLKKA-NLQIDQINTDLNLERSHAQKNENARQQ 1204
Query: 402 SIEEKKTLQENIDDL--------RTDLLESELRVKDLVRELD----EKESILETKQCVQK 449
+ K L+ + ++ + + E ++ L +LD E+++ + + +K
Sbjct: 1205 LERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEK 1264
Query: 450 ELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKL 486
+L+ ++ + E+YK + + +LK +L
Sbjct: 1265 KLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQL 1301
Score = 32.3 bits (70), Expect = 6.1
Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 4/102 (3%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLL--ESELRVKDLVRELDEKESILETKQCVQ 448
+L E+E + + EK LQE + T+L ELR + L + E E I +
Sbjct: 731 RLTEMETLQSQLMAEKLQLQEQL-QAETELCAEAEELRAR-LTAKKQELEEICHDLEARV 788
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEK 490
+E E L+ K ++++ + L E+ EE + + KL EK
Sbjct: 789 EEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEK 830
>AL049569-4|CAI20365.1| 1898|Homo sapiens ciliary rootlet
coiled-coil, rootletin protein.
Length = 1898
Score = 46.8 bits (106), Expect = 3e-04
Identities = 52/259 (20%), Positives = 113/259 (43%), Gaps = 20/259 (7%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSI-EEKKTLQENIDDLRTDLLESELRVKDLVREL 434
+S ++ N+A +++ ++ + + +E++ LQ ++LR R +D + E
Sbjct: 476 RSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELR--------RQRDRLEE- 526
Query: 435 DEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKD 494
E+E ++ V++ELE + HR+ E E KR + K E+ E++ LS +D
Sbjct: 527 -EQEDAVQDGARVRRELERS-----HRQLEQLEGKRSVLAK--ELVEVREALSRATLQRD 578
Query: 495 IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVG 554
+ +++++ L + ++++ L E A D L D+
Sbjct: 579 MLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKL-DLN 637
Query: 555 NMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEE 614
++ Q ++ L RQ + +++ E +RL E EQE E +++ + +E
Sbjct: 638 RLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQE 697
Query: 615 E-HMNIINLLHNKLELRNE 632
+ L H + +L+ +
Sbjct: 698 ALEQQLPTLRHERSQLQEQ 716
Score = 32.7 bits (71), Expect = 4.6
Identities = 23/96 (23%), Positives = 47/96 (48%), Gaps = 3/96 (3%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKE 450
+L+E ++K +S E ++ ++ +LR L E + L R +E S ++ + +
Sbjct: 1057 ELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERIS 1116
Query: 451 LESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKL 486
L+ D E + +EE + + G+E EL++ L
Sbjct: 1117 LKLANEDKEQKLALLEEARTAV---GKEAGELRTGL 1149
Score = 31.9 bits (69), Expect = 8.0
Identities = 26/120 (21%), Positives = 55/120 (45%), Gaps = 4/120 (3%)
Query: 378 IKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRV-KDLVRELDE 436
++DM+ + L + K+ +DS E++ L+E + LR D + ++ +D RE+
Sbjct: 416 VQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLR-DKTDGAMQAHEDAQREVQR 474
Query: 437 KESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEK--AIKD 494
S E + L + + + E+ + + L EE+ + +L E+ A++D
Sbjct: 475 LRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQD 534
>AL049569-3|CAI20363.1| 2017|Homo sapiens ciliary rootlet
coiled-coil, rootletin protein.
Length = 2017
Score = 46.8 bits (106), Expect = 3e-04
Identities = 52/259 (20%), Positives = 113/259 (43%), Gaps = 20/259 (7%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSI-EEKKTLQENIDDLRTDLLESELRVKDLVREL 434
+S ++ N+A +++ ++ + + +E++ LQ ++LR R +D + E
Sbjct: 595 RSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELR--------RQRDRLEE- 645
Query: 435 DEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKD 494
E+E ++ V++ELE + HR+ E E KR + K E+ E++ LS +D
Sbjct: 646 -EQEDAVQDGARVRRELERS-----HRQLEQLEGKRSVLAK--ELVEVREALSRATLQRD 697
Query: 495 IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVG 554
+ +++++ L + ++++ L E A D L D+
Sbjct: 698 MLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKL-DLN 756
Query: 555 NMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEE 614
++ Q ++ L RQ + +++ E +RL E EQE E +++ + +E
Sbjct: 757 RLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQE 816
Query: 615 E-HMNIINLLHNKLELRNE 632
+ L H + +L+ +
Sbjct: 817 ALEQQLPTLRHERSQLQEQ 835
Score = 32.7 bits (71), Expect = 4.6
Identities = 23/96 (23%), Positives = 47/96 (48%), Gaps = 3/96 (3%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKE 450
+L+E ++K +S E ++ ++ +LR L E + L R +E S ++ + +
Sbjct: 1176 ELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERIS 1235
Query: 451 LESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKL 486
L+ D E + +EE + + G+E EL++ L
Sbjct: 1236 LKLANEDKEQKLALLEEARTAV---GKEAGELRTGL 1268
Score = 31.9 bits (69), Expect = 8.0
Identities = 26/120 (21%), Positives = 55/120 (45%), Gaps = 4/120 (3%)
Query: 378 IKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRV-KDLVRELDE 436
++DM+ + L + K+ +DS E++ L+E + LR D + ++ +D RE+
Sbjct: 535 VQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLR-DKTDGAMQAHEDAQREVQR 593
Query: 437 KESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEK--AIKD 494
S E + L + + + E+ + + L EE+ + +L E+ A++D
Sbjct: 594 LRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQD 653
>AF273044-1|AAG34904.1| 761|Homo sapiens CTCL tumor antigen se2-2
protein.
Length = 761
Score = 46.8 bits (106), Expect = 3e-04
Identities = 55/250 (22%), Positives = 108/250 (43%), Gaps = 24/250 (9%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKE 450
++ E++ K ++I K LQEN +D ++ + + V+DL LD+ + + QC++ E
Sbjct: 31 EITELKVKEFENI--KLQLQENHED---EVKKVKAEVEDLKYLLDQSQ---KESQCLKSE 82
Query: 451 LESTKTDLEHRKTE-----IEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXX 505
L++ K T +E K L K ++ L L +A
Sbjct: 83 LQAQKEANSRAPTTTMRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISAT 142
Query: 506 XXXXXXXXXXXXXXR-----ESQMKSYYEELMNLKNQI--TQLREFGAFDNLNDVGNMIN 558
R ++Q++ E L+ LK + ++ RE DNLND+ N +
Sbjct: 143 SQKEAHLNVQQIVDRHTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQ 202
Query: 559 QQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMN 618
+++ ++ + +EE D++ + +IKRL + + NK+ ++ E + +
Sbjct: 203 KKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQGKPLTDNKQ----SLIEELQRKVKK 258
Query: 619 IINLLHNKLE 628
+ N L K+E
Sbjct: 259 LENQLEGKVE 268
Score = 33.9 bits (74), Expect = 2.0
Identities = 33/132 (25%), Positives = 62/132 (46%), Gaps = 15/132 (11%)
Query: 374 YNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRE 433
+ + +K ++N N+ KL E K S + +L +N++DL +L + + ++RE
Sbjct: 158 HTRELKTQVEDLNENLLKLKEALKT---SKNRENSLTDNLNDLNNELQKKQKAYNKILRE 214
Query: 434 LDE--------KESILETKQCVQ-KELESTKTDL-EHRKTEIEEYKRLLFEKGEEID--E 481
+E K I +Q K L K L E + ++++ + L K EE+D
Sbjct: 215 KEEIDQENDELKRQIKRLTSGLQGKPLTDNKQSLIEELQRKVKKLENQLEGKVEEVDLKP 274
Query: 482 LKSKLSTEKAIK 493
+K K + E+ I+
Sbjct: 275 MKEKNAKEELIR 286
>AB007914-1|BAA32290.2| 1919|Homo sapiens KIAA0445 protein protein.
Length = 1919
Score = 46.8 bits (106), Expect = 3e-04
Identities = 52/259 (20%), Positives = 113/259 (43%), Gaps = 20/259 (7%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSI-EEKKTLQENIDDLRTDLLESELRVKDLVREL 434
+S ++ N+A +++ ++ + + +E++ LQ ++LR R +D + E
Sbjct: 497 RSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELR--------RQRDRLEE- 547
Query: 435 DEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKD 494
E+E ++ V++ELE + HR+ E E KR + K E+ E++ LS +D
Sbjct: 548 -EQEDAVQDGARVRRELERS-----HRQLEQLEGKRSVLAK--ELVEVREALSRATLQRD 599
Query: 495 IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVG 554
+ +++++ L + ++++ L E A D L D+
Sbjct: 600 MLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKL-DLN 658
Query: 555 NMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEE 614
++ Q ++ L RQ + +++ E +RL E EQE E +++ + +E
Sbjct: 659 RLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQE 718
Query: 615 E-HMNIINLLHNKLELRNE 632
+ L H + +L+ +
Sbjct: 719 ALEQQLPTLRHERSQLQEQ 737
Score = 32.7 bits (71), Expect = 4.6
Identities = 23/96 (23%), Positives = 47/96 (48%), Gaps = 3/96 (3%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKE 450
+L+E ++K +S E ++ ++ +LR L E + L R +E S ++ + +
Sbjct: 1078 ELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERIS 1137
Query: 451 LESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKL 486
L+ D E + +EE + + G+E EL++ L
Sbjct: 1138 LKLANEDKEQKLALLEEARTAV---GKEAGELRTGL 1170
Score = 31.9 bits (69), Expect = 8.0
Identities = 26/120 (21%), Positives = 55/120 (45%), Gaps = 4/120 (3%)
Query: 378 IKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRV-KDLVRELDE 436
++DM+ + L + K+ +DS E++ L+E + LR D + ++ +D RE+
Sbjct: 437 VQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLR-DKTDGAMQAHEDAQREVQR 495
Query: 437 KESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEK--AIKD 494
S E + L + + + E+ + + L EE+ + +L E+ A++D
Sbjct: 496 LRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQD 555
>AB002371-1|BAA20828.2| 1540|Homo sapiens KIAA0373 protein.
Length = 1540
Score = 46.8 bits (106), Expect = 3e-04
Identities = 55/250 (22%), Positives = 108/250 (43%), Gaps = 24/250 (9%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKE 450
++ E++ K ++I K LQEN +D ++ + + V+DL LD+ + + QC++ E
Sbjct: 717 EITELKVKEFENI--KLQLQENHED---EVKKVKAEVEDLKYLLDQSQ---KESQCLKSE 768
Query: 451 LESTKTDLEHRKTE-----IEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXX 505
L++ K T +E K L K ++ L L +A
Sbjct: 769 LQAQKEANSRAPTTTMRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISAT 828
Query: 506 XXXXXXXXXXXXXXR-----ESQMKSYYEELMNLKNQI--TQLREFGAFDNLNDVGNMIN 558
R ++Q++ E L+ LK + ++ RE DNLND+ N +
Sbjct: 829 SQKEAHLNVQQIVDRHTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQ 888
Query: 559 QQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMN 618
+++ ++ + +EE D++ + +IKRL + + NK+ ++ E + +
Sbjct: 889 KKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQGKPLTDNKQ----SLIEELQRKVKK 944
Query: 619 IINLLHNKLE 628
+ N L K+E
Sbjct: 945 LENQLEGKVE 954
Score = 35.5 bits (78), Expect = 0.65
Identities = 46/222 (20%), Positives = 92/222 (41%), Gaps = 13/222 (5%)
Query: 420 LLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEI 479
+LE+ K L +L EKES L + + +L R E ++L+ E G +
Sbjct: 528 ILETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPATAEREKLIAELGRKE 587
Query: 480 DELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQ---MKSYYEELMNLKN 536
E KS + + A + I RE Q +K + E+L L +
Sbjct: 588 MEPKSHHTLKIAHQTIANMQARLNQKEEVLKKYQRLLEKAREEQREIVKKHEEDLHILHH 647
Query: 537 QI-----TQLREF--GAFDNLNDVGNMI--NQQRDKLFELTKRQEEYDEKLQTKENEIKR 587
++ + L +F A+D + + N+ +L E+ + E D+ L + ++K+
Sbjct: 648 RLELQADSSLNKFKQTAWDLMKQSPTPVPTNKHFIRLAEMEQTVAEQDDSLSSLLVKLKK 707
Query: 588 LVESMTEQEHVLNKKEKEIKMLN-EKEEEHMNIINLLHNKLE 628
+ + + Q + K KE + + + +E H + + + ++E
Sbjct: 708 VSQDLERQREITELKVKEFENIKLQLQENHEDEVKKVKAEVE 749
Score = 33.9 bits (74), Expect = 2.0
Identities = 33/132 (25%), Positives = 62/132 (46%), Gaps = 15/132 (11%)
Query: 374 YNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRE 433
+ + +K ++N N+ KL E K S + +L +N++DL +L + + ++RE
Sbjct: 844 HTRELKTQVEDLNENLLKLKEALKT---SKNRENSLTDNLNDLNNELQKKQKAYNKILRE 900
Query: 434 LDE--------KESILETKQCVQ-KELESTKTDL-EHRKTEIEEYKRLLFEKGEEID--E 481
+E K I +Q K L K L E + ++++ + L K EE+D
Sbjct: 901 KEEIDQENDELKRQIKRLTSGLQGKPLTDNKQSLIEELQRKVKKLENQLEGKVEEVDLKP 960
Query: 482 LKSKLSTEKAIK 493
+K K + E+ I+
Sbjct: 961 MKEKNAKEELIR 972
Score = 31.9 bits (69), Expect = 8.0
Identities = 20/84 (23%), Positives = 46/84 (54%), Gaps = 7/84 (8%)
Query: 560 QRDKLF-ELTKRQEE--YDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEE- 615
+R+KL EL +++ E L+ I + + ++E VL K ++ ++ E++ E
Sbjct: 575 EREKLIAELGRKEMEPKSHHTLKIAHQTIANMQARLNQKEEVLKKYQRLLEKAREEQREI 634
Query: 616 ---HMNIINLLHNKLELRNEADID 636
H +++LH++LEL+ ++ ++
Sbjct: 635 VKKHEEDLHILHHRLELQADSSLN 658
>BX538286-1|CAD98081.1| 724|Homo sapiens hypothetical protein
protein.
Length = 724
Score = 46.4 bits (105), Expect = 3e-04
Identities = 83/491 (16%), Positives = 186/491 (37%), Gaps = 35/491 (7%)
Query: 177 KEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQN 236
K++ E L + +++LRT+ ++ + D A+ T QL +EL S+ +
Sbjct: 232 KQYEKERQGLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLE 291
Query: 237 AEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKD-RLSRAEHQLKTNVERVVQ 295
+EM K+ +M + +L + + Q K + +
Sbjct: 292 SEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMLEAQLEKKDQQFKEQEKTMSM 351
Query: 296 LEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREK 355
L+ + + SL+R + D+ L L + + T + + A E
Sbjct: 352 LQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEI 411
Query: 356 LQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDD 415
+ + K +K E+ + K ++I+ N S++E T ++N+
Sbjct: 412 RKEELVLHLNQLEGNKEKFEKQLKKKSEEVYC-LQKELKIK---NHSLQE--TSEQNVI- 464
Query: 416 LRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIE-EYKRLLFE 474
L L +++ +L+ + ELE T+T LE + +++E E ++
Sbjct: 465 --------------LQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRES 510
Query: 475 KGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNL 534
E++ +++ K + D+ + +M Y EEL +
Sbjct: 511 SAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQV----------KIEMDQYKEELSKM 560
Query: 535 KNQITQLREFGAFD--NLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESM 592
+ +I L+ G +L+ + +++Q + +L + T +E ++ + E E+ ++
Sbjct: 561 EKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKR 620
Query: 593 TEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVL 652
E L E+K + +E +++ LE + D+ L + K +
Sbjct: 621 EVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKK 680
Query: 653 EKMSISNRVLK 663
+++ ++ LK
Sbjct: 681 QELLEMDQALK 691
Score = 37.1 bits (82), Expect = 0.21
Identities = 85/423 (20%), Positives = 166/423 (39%), Gaps = 48/423 (11%)
Query: 114 KALEHSTLDNKVTFDVNKLLNIPNSLVDKC-------------EETLFKRKEIINWFESL 160
KA S L++++T ++LL + L +K E+ L ++ +
Sbjct: 283 KASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMLEAQLEKKDQQF 342
Query: 161 MSQEKGISTKTLTMKIKEFNAEN--DLLKSSLDQLRTEFLKEINDIIDCLRKNANETM-- 216
QEK +S + K+ + E+ LL S +++ E +K+ + + + ET+
Sbjct: 343 KEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKV 402
Query: 217 -----ALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXX 271
AL++R +EL L+ L + KQ+ Y +
Sbjct: 403 RQLDSALEIRKEELVLHLNQLEGNKEKFEKQLKKKSEE-VYCLQKELKIKNHSLQETSEQ 461
Query: 272 XSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQ- 330
I++ L + + L+ R +LE + + LE+ + ++
Sbjct: 462 NVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEK 521
Query: 331 ------ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSAS-YNKSIKDMKH 383
E + Q + + T + + ++ + NK++ +
Sbjct: 522 CESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQL 581
Query: 384 EMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTD------LLESELR-----VKDLVR 432
+M L+ K E+EKK N +++E + LQ + + T+ +LE+EL+ +K +R
Sbjct: 582 DMILDQTKT-ELEKKTN-AVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLR 639
Query: 433 ELDEKESILETKQCVQKELESTKTDL--EHR--KTEIEEYKRLLFEKGEEIDELKSKLST 488
+L E +L+ Q +E +T DL E R K EIE+ K+ L E + + E +L
Sbjct: 640 QLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQ 699
Query: 489 EKA 491
A
Sbjct: 700 RAA 702
>BC051733-1|AAH51733.1| 1026|Homo sapiens LUZP1 protein protein.
Length = 1026
Score = 46.4 bits (105), Expect = 3e-04
Identities = 57/252 (22%), Positives = 110/252 (43%), Gaps = 9/252 (3%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLR--TDLLESELRVKDL-VR 432
+ +K + +A+L ++E+ ++ S + L ++++ R T + SEL + + V+
Sbjct: 104 RELKSEIERLQKRMAELEKLEEAFSRSKNDCTQLCLSLNEERNLTKKISSELEMLRVKVK 163
Query: 433 ELDEKESILE-TKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
EL+ E L+ T+Q + ELE K+ +E + E + I EL KL K
Sbjct: 164 ELESSEDRLDKTEQSLASELEKLKSLTLSFVSERKYLNEKEKENEKLIKELTQKLEQNKK 223
Query: 492 I-KDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNL 550
+ +D +ES+ K + L ++N+ E N
Sbjct: 224 MNRDYTRNASNLERNDLRIEDGISSTLPSKESRRKGGLDYLKQVENETRNKSENEKNRNQ 283
Query: 551 NDVG-NMINQQRDKLFELTKRQEEYDE---KLQTKENEIKRLVESMTEQEHVLNKKEKEI 606
D +NQ+ +KL K E +E K+++K N+++ S + +L + +EI
Sbjct: 284 EDNKVKDLNQEIEKLKTQIKHFESLEEELKKMKSKNNDLQDNYLSEQNKNKLLASQLEEI 343
Query: 607 KMLNEKEEEHMN 618
K+ +K++E N
Sbjct: 344 KLQIKKQKELEN 355
Score = 43.6 bits (98), Expect = 0.002
Identities = 60/298 (20%), Positives = 121/298 (40%), Gaps = 15/298 (5%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESEL-RVKDLVRELDEKESILETKQCVQK 449
K+I+ E + + E + L++ + LR + + E+ R +DL R + EK LE ++ + +
Sbjct: 50 KVIQAEGSNSSMLAEIEVLRQRV--LRIEGKDEEIKRAEDLCRLMKEK---LEEEENLTR 104
Query: 450 ELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXX 509
EL+S L+ R E+E+ + + +L L+ E+ +
Sbjct: 105 ELKSEIERLQKRMAELEKLEEAFSRSKNDCTQLCLSLNEERNLTKKISSELEMLRVKVKE 164
Query: 510 XXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTK 569
E + S E+L +L R++ + + +I + KL + K
Sbjct: 165 LESSEDRLDKTEQSLASELEKLKSLTLSFVSERKY-LNEKEKENEKLIKELTQKLEQNKK 223
Query: 570 RQEEYDEKLQTKENEIKRLVE--SMTEQEHVLNKKE-----KEIKMLNEKEEEHMNIINL 622
+Y E R+ + S T +K K+++ + E+ N
Sbjct: 224 MNRDYTRNASNLERNDLRIEDGISSTLPSKESRRKGGLDYLKQVENETRNKSENEKNRNQ 283
Query: 623 LHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRTLRKNM 680
NK++ N+ +I+ + T K+ +SL L+KM N L+ + L +++ L +
Sbjct: 284 EDNKVKDLNQ-EIEKLKTQIKHFESLEEELKKMKSKNNDLQDNYLSEQNKNKLLASQL 340
>AL031428-1|CAI19705.1| 1026|Homo sapiens leucine zipper protein 1
protein.
Length = 1026
Score = 46.4 bits (105), Expect = 3e-04
Identities = 57/252 (22%), Positives = 110/252 (43%), Gaps = 9/252 (3%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLR--TDLLESELRVKDL-VR 432
+ +K + +A+L ++E+ ++ S + L ++++ R T + SEL + + V+
Sbjct: 104 RELKSEIERLQKRMAELEKLEEAFSRSKNDCTQLCLSLNEERNLTKKISSELEMLRVKVK 163
Query: 433 ELDEKESILE-TKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
EL+ E L+ T+Q + ELE K+ +E + E + I EL KL K
Sbjct: 164 ELESSEDRLDKTEQSLASELEKLKSLTLSFVSERKYLNEKEKENEKLIKELTQKLEQNKK 223
Query: 492 I-KDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNL 550
+ +D +ES+ K + L ++N+ E N
Sbjct: 224 MNRDYTRNASNLERNDLRIEDGISSTLPSKESRRKGGLDYLKQVENETRNKSENEKNRNQ 283
Query: 551 NDVG-NMINQQRDKLFELTKRQEEYDE---KLQTKENEIKRLVESMTEQEHVLNKKEKEI 606
D +NQ+ +KL K E +E K+++K N+++ S + +L + +EI
Sbjct: 284 EDNKVKDLNQEIEKLKTQIKHFESLEEELKKMKSKNNDLQDNYLSEQNKNKLLASQLEEI 343
Query: 607 KMLNEKEEEHMN 618
K+ +K++E N
Sbjct: 344 KLQIKKQKELEN 355
Score = 43.6 bits (98), Expect = 0.002
Identities = 60/298 (20%), Positives = 121/298 (40%), Gaps = 15/298 (5%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESEL-RVKDLVRELDEKESILETKQCVQK 449
K+I+ E + + E + L++ + LR + + E+ R +DL R + EK LE ++ + +
Sbjct: 50 KVIQAEGSNSSMLAEIEVLRQRV--LRIEGKDEEIKRAEDLCRLMKEK---LEEEENLTR 104
Query: 450 ELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXX 509
EL+S L+ R E+E+ + + +L L+ E+ +
Sbjct: 105 ELKSEIERLQKRMAELEKLEEAFSRSKNDCTQLCLSLNEERNLTKKISSELEMLRVKVKE 164
Query: 510 XXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTK 569
E + S E+L +L R++ + + +I + KL + K
Sbjct: 165 LESSEDRLDKTEQSLASELEKLKSLTLSFVSERKY-LNEKEKENEKLIKELTQKLEQNKK 223
Query: 570 RQEEYDEKLQTKENEIKRLVE--SMTEQEHVLNKKE-----KEIKMLNEKEEEHMNIINL 622
+Y E R+ + S T +K K+++ + E+ N
Sbjct: 224 MNRDYTRNASNLERNDLRIEDGISSTLPSKESRRKGGLDYLKQVENETRNKSENEKNRNQ 283
Query: 623 LHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRTLRKNM 680
NK++ N+ +I+ + T K+ +SL L+KM N L+ + L +++ L +
Sbjct: 284 EDNKVKDLNQ-EIEKLKTQIKHFESLEEELKKMKSKNNDLQDNYLSEQNKNKLLASQL 340
>AK074153-1|BAB84979.1| 1046|Homo sapiens FLJ00226 protein protein.
Length = 1046
Score = 46.4 bits (105), Expect = 3e-04
Identities = 57/252 (22%), Positives = 110/252 (43%), Gaps = 9/252 (3%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLR--TDLLESELRVKDL-VR 432
+ +K + +A+L ++E+ ++ S + L ++++ R T + SEL + + V+
Sbjct: 97 RELKSEIERLQKRMAELEKLEEAFSRSKNDCTQLCLSLNEERNLTKKISSELEMLRVKVK 156
Query: 433 ELDEKESILE-TKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
EL+ E L+ T+Q + ELE K+ +E + E + I EL KL K
Sbjct: 157 ELESSEDRLDKTEQSLASELEKLKSLTLSFVSERKYLNEKEKENEKLIKELTQKLEQNKK 216
Query: 492 I-KDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNL 550
+ +D +ES+ K + L ++N+ E N
Sbjct: 217 MNRDYTRNASNLERNDLRIEDGISSTLPSKESRRKGGLDYLKQVENETRNKSENEKNRNQ 276
Query: 551 NDVG-NMINQQRDKLFELTKRQEEYDE---KLQTKENEIKRLVESMTEQEHVLNKKEKEI 606
D +NQ+ +KL K E +E K+++K N+++ S + +L + +EI
Sbjct: 277 EDNKVKDLNQEIEKLKTQIKHFESLEEELKKMKSKNNDLQDNYLSEQNKNKLLASQLEEI 336
Query: 607 KMLNEKEEEHMN 618
K+ +K++E N
Sbjct: 337 KLQIKKQKELEN 348
Score = 43.6 bits (98), Expect = 0.002
Identities = 60/298 (20%), Positives = 121/298 (40%), Gaps = 15/298 (5%)
Query: 391 KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESEL-RVKDLVRELDEKESILETKQCVQK 449
K+I+ E + + E + L++ + LR + + E+ R +DL R + EK LE ++ + +
Sbjct: 43 KVIQAEGSNSSMLAEIEVLRQRV--LRIEGKDEEIKRAEDLCRLMKEK---LEEEENLTR 97
Query: 450 ELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXX 509
EL+S L+ R E+E+ + + +L L+ E+ +
Sbjct: 98 ELKSEIERLQKRMAELEKLEEAFSRSKNDCTQLCLSLNEERNLTKKISSELEMLRVKVKE 157
Query: 510 XXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTK 569
E + S E+L +L R++ + + +I + KL + K
Sbjct: 158 LESSEDRLDKTEQSLASELEKLKSLTLSFVSERKY-LNEKEKENEKLIKELTQKLEQNKK 216
Query: 570 RQEEYDEKLQTKENEIKRLVE--SMTEQEHVLNKKE-----KEIKMLNEKEEEHMNIINL 622
+Y E R+ + S T +K K+++ + E+ N
Sbjct: 217 MNRDYTRNASNLERNDLRIEDGISSTLPSKESRRKGGLDYLKQVENETRNKSENEKNRNQ 276
Query: 623 LHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRTLRKNM 680
NK++ N+ +I+ + T K+ +SL L+KM N L+ + L +++ L +
Sbjct: 277 EDNKVKDLNQ-EIEKLKTQIKHFESLEEELKKMKSKNNDLQDNYLSEQNKNKLLASQL 333
>AK023707-1|BAB14650.1| 435|Homo sapiens protein ( Homo sapiens
cDNA FLJ13645 fis, clone PLACE1011310, weakly similar to
MYOSIN HEAVY CHAIN, GIZZARD SMOOTH MUSCLE. ).
Length = 435
Score = 46.4 bits (105), Expect = 3e-04
Identities = 47/259 (18%), Positives = 110/259 (42%), Gaps = 12/259 (4%)
Query: 432 RELDEKESILETKQCVQKELESTKTDLEHRKTEIEEY-KRLLFEKGEEIDELKSKLSTEK 490
RE + I +Q +K++ S + ++E K ++ K + E ++ L+ K + EK
Sbjct: 17 RETQSLDVIFTERQAKEKQIRSVEEEIEQEKQATDDIIKNMSLEN--QVKYLEMKTTNEK 74
Query: 491 AIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSY-YEELMNLKNQITQL----REFG 545
++++ + Q +E+L L++ Q+ + G
Sbjct: 75 LLQELDTLQQQLDSQNMKKESLEAEIAHSQVKQEAVLLHEKLYELESHRDQMIAEDKSIG 134
Query: 546 A-FDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEK 604
+ + + I ++ + ++ + EK+ EI++L + E + +N+K K
Sbjct: 135 SPMEEREKLLKQIKDDNQEIASMERQLTDTKEKINQFIEEIRQLDMDLEEHQGEMNQKYK 194
Query: 605 EIKMLNEKEEEHMNIINLLHNKLELRNEADID--VIITLAKYKKSLTLVLEKMSISNRVL 662
E+K E + + N+ EL+ +A I+ ++ L +++ + + SI+N+ L
Sbjct: 195 ELKKREEHMDTFIETFEETKNQ-ELKRKAQIEANIVALLEHCSRNINRIEQISSITNQEL 253
Query: 663 KCSLLGVVTQSRTLRKNMS 681
K + +S ++K+ S
Sbjct: 254 KMMQDDLNFKSTEVQKSQS 272
Score = 32.3 bits (70), Expect = 6.1
Identities = 51/252 (20%), Positives = 100/252 (39%), Gaps = 21/252 (8%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD 435
K IKD E+ +L + ++K N IEE + L ++++ + ++ + +K +D
Sbjct: 145 KQIKDDNQEIASMERQLTDTKEKINQFIEEIRQLDMDLEEHQGEMNQKYKELKKREEHMD 204
Query: 436 E-KESILETKQCVQKELESTKTD----LEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEK 490
E+ ETK K + + LEH I +++ +E+ ++ L+ +
Sbjct: 205 TFIETFEETKNQELKRKAQIEANIVALLEHCSRNINRIEQISSITNQELKMMQDDLNFKS 264
Query: 491 AIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNL 550
ES+M EE +LK++I Q+ +
Sbjct: 265 TEVQKSQSTAQNLTSDIQRLQLDLQKMELLESKMT---EEQHSLKSKIKQMTT--DLEIY 319
Query: 551 NDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLN 610
ND+ + + +K+ +L QE L T N K+++E N + + +K
Sbjct: 320 NDLPALKSSGEEKIKKL--HQERM--ILSTHRNAFKKIMEKQ-------NIEYEALKTQL 368
Query: 611 EKEEEHMNIINL 622
++ E H + NL
Sbjct: 369 QENETHSQLTNL 380
>AB231311-1|BAE78964.1| 390|Homo sapiens Nucb2 splice variant
protein.
Length = 390
Score = 46.4 bits (105), Expect = 3e-04
Identities = 46/186 (24%), Positives = 82/186 (44%), Gaps = 10/186 (5%)
Query: 451 LESTKTDLEHR-KTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXX 509
+++ +DLEH KT EE+K+ K E E L+ EK ++
Sbjct: 159 IKAATSDLEHYDKTRHEEFKKYEMMKEHERREYLKTLNEEKRKEE----ESKFEEMKKKH 214
Query: 510 XXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTK 569
+ Q+K +EE L + F ++N G + Q+ + LF TK
Sbjct: 215 ENHPKVNHPGSKDQLKEVWEETDGLDPNDFDPKTFFKLHDVNSDGFLDEQELEALF--TK 272
Query: 570 RQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKE-EEHMNIINLLHNKLE 628
E+ + +++ ++ E + +EHV+N+ + + E+E +E+ NII L N E
Sbjct: 273 ELEKVYDPKNEEDDMVEMEEERLRMREHVMNETLDQQQFFTEEELKEYENIIALQEN--E 330
Query: 629 LRNEAD 634
L+ +AD
Sbjct: 331 LKKKAD 336
Score = 31.9 bits (69), Expect = 8.0
Identities = 22/101 (21%), Positives = 53/101 (52%), Gaps = 4/101 (3%)
Query: 529 EELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQ-EEYDEKLQTKENEIKR 587
E++ + KN+ + E + L +++N+ D+ T+ + +EY+ + +ENE+K+
Sbjct: 275 EKVYDPKNEEDDMVEMEE-ERLRMREHVMNETLDQQQFFTEEELKEYENIIALQENELKK 333
Query: 588 LVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
+ + +Q+ L ++ +++ +K E H I + KL+
Sbjct: 334 KADELQKQKEELQRQHDQLEA--QKLEYHQVIQQMEQKKLQ 372
>AB208965-1|BAD92202.1| 705|Homo sapiens Rho-associated,
coiled-coil containing protein kinase 1 variant protein.
Length = 705
Score = 46.4 bits (105), Expect = 3e-04
Identities = 123/614 (20%), Positives = 236/614 (38%), Gaps = 69/614 (11%)
Query: 11 NQTDGCLYEDLNEQ-ESITSESHKITKLKTVWQEKMVT----FEKSKKELEDRQNQVMEL 65
+ D L E L + + + H +LK ++K T +K KEL++ NQ L
Sbjct: 96 SNADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNL 155
Query: 66 YASLRNTHRKMKLLGQKVN-------LPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEH 118
+++ ++ LL ++N + + ++ N +QL L K ++
Sbjct: 156 ESTVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDL-----KKVSQN 210
Query: 119 STLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKE 178
S L N+ + K L N L+ +T + ++ +SQ + ++ +E
Sbjct: 211 SQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLN--------RE 262
Query: 179 FNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMA----LQLRTKELSCALSDL-- 232
N +L++S Q ++ ++ I++ R++ LQ R L + L
Sbjct: 263 LQERNRILENSKSQTDKDYY-QLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKH 321
Query: 233 NTQNAE-MRKQIHSGDHH--RPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRA----EHQ 285
N + E RK+ +H + N + + ++++A +HQ
Sbjct: 322 NLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQ 381
Query: 286 LKTNVERVV--QLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNT 343
+ V ++E L++ R E V D Q KL + + N
Sbjct: 382 SIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKL-EHLTGNK 440
Query: 344 THLED------IALAREKLQSXXXXXXXXXXXXSASYNKSI-KDMKHEMN--LNIAKLIE 394
+ED + L +E + A K + K MK E+N L +L+E
Sbjct: 441 ERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLE 500
Query: 395 IE-----KKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEK--ESILETKQCV 447
E K+Y + + + LQ+ ++ + + +VK+L E++EK E++ + ++
Sbjct: 501 FELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQ 560
Query: 448 -QKELESTKTDLEHRKTEIEEYKRLL-----FEKGEEIDELKSKLSTEKAIKD--IXXXX 499
+KE +T+ DL K E E+ R L FE +E + S+ E KD +
Sbjct: 561 NEKETLATQLDLAETKAESEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTVSRLE 620
Query: 500 XXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFD-NLNDVGNMIN 558
E K+ E + + +I+ L+ AF+ N+N +
Sbjct: 621 EANSMLTKDIEILRRENEELTEKMKKAEEEYKLEKEEEISNLK--AAFEKNINTERTLKT 678
Query: 559 QQRDKLFELTKRQE 572
Q +KL E+ R++
Sbjct: 679 QAVNKLAEIMNRKD 692
Score = 38.7 bits (86), Expect = 0.070
Identities = 65/319 (20%), Positives = 136/319 (42%), Gaps = 29/319 (9%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLR---TDLLESELRVKDLVR 432
+ +K + L KL +++K+ ++ + +T + LR T++ +S +++ L R
Sbjct: 202 EDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNR 261
Query: 433 ELDEKESILETKQC--------VQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKS 484
EL E+ ILE + +Q LE+ + D H I + + + EE+ LK
Sbjct: 262 ELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKH 321
Query: 485 KLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREF 544
L EK ++ + ++ E+ +N ++++T+ R
Sbjct: 322 NL--EK-VEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVN-EHKVTKARLT 377
Query: 545 GAFDNLNDVGNM-INQQRDKLFELTKRQEEYDEKLQTKENEIKR----LVESMTEQEHVL 599
++ + ++ + + KL E + +E+ + ++ E + L +S + EH+
Sbjct: 378 DKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLT 437
Query: 600 NKKEK---EIKMLNEKEEEHMNIINLLHNKLELRN-EADIDVIITLAKYKKSLTLVLEKM 655
KE+ E+K L + E+ N LL N+L+ + EAD L +K + + +
Sbjct: 438 GNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEAD-----NLKGLEKQMKQEINTL 492
Query: 656 SISNRVLKCSLLGVVTQSR 674
+ R+L+ L + Q R
Sbjct: 493 LEAKRLLEFELAQLTKQYR 511
Score = 38.3 bits (85), Expect = 0.092
Identities = 50/262 (19%), Positives = 113/262 (43%), Gaps = 19/262 (7%)
Query: 414 DDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLF 473
D++ S +++ +++ELDE+ + + ++E K L+HR I EY+R
Sbjct: 125 DEMEQKCRTSNIKLDKIMKELDEEGNQRRNLESTVSQIEKEKMLLQHR---INEYQRKAE 181
Query: 474 EKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMN 533
++ E+ +++++ST K + +++ + +
Sbjct: 182 QENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVR 241
Query: 534 LKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYD-----EKLQTKENEIKRL 588
L+ T++ + + L + + Q+R+++ E +K Q + D L+ + +
Sbjct: 242 LRKSHTEMSK--SISQLESLNREL-QERNRILENSKSQTDKDYYQLQAILEAERRDRGHD 298
Query: 589 VESMTEQEHVLNKKEKEIKMLN---EK-EEEHMNIINLLHNKLELRNEADIDVIITLAKY 644
E + + + + ++E+K L EK E E ++L++ + +N +ID+ L
Sbjct: 299 SEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKL--- 355
Query: 645 KKSLTLVLEKMSISNRVLKCSL 666
KSL LE+ ++V K L
Sbjct: 356 -KSLQQRLEQEVNEHKVTKARL 376
>BC080545-1|AAH80545.1| 498|Homo sapiens MYH11 protein protein.
Length = 498
Score = 46.0 bits (104), Expect = 5e-04
Identities = 82/458 (17%), Positives = 171/458 (37%), Gaps = 22/458 (4%)
Query: 162 SQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLR 221
++EK +L ++E + L+ + L+ E ++++ D + KN +E L+
Sbjct: 4 AREKETKALSLARALEEALEAKEELERTNKMLKAE-MEDLVSSKDDVGKNVHE---LEKS 59
Query: 222 TKELSCALSDLNTQNAEMRKQIHSGDHH--RPYANRNXXXXXXXXXXXXXXXXSIMKDR- 278
+ L + ++ TQ E+ ++ + + R N + K R
Sbjct: 60 KRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQ 119
Query: 279 LSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQS 338
L R H+ +T +E + A A+ + + + E+ ++L KL
Sbjct: 120 LQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQ 179
Query: 339 IKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKK 398
+KD LED +R+++ + A + +D+ K ++EK+
Sbjct: 180 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERAR--KQADLEKE 237
Query: 399 YNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILET------KQCVQKELE 452
+ EE + + L+ + E R+ L EL+E++ +E K Q E
Sbjct: 238 --ELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQL 295
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKL-STEKAIKD-IXXXXXXXXXXXXXXX 510
S + E + E R E+ + EL+SKL E A+K
Sbjct: 296 SNELATERSTAQKNESARQQLERQNK--ELRSKLHEMEGAVKSKFKSTIAALEAKIAQLE 353
Query: 511 XXXXXXXXXRESQMKSYYEELMNLKNQITQLR-EFGAFDNLNDVGNMINQQRDKLFELTK 569
+++ KS ++ LK + Q+ E + + N + +L +
Sbjct: 354 EQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE 413
Query: 570 RQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK 607
EE +++ +++R ++ TE + ++ +K
Sbjct: 414 EAEEESQRINANRRKLQRELDEATESNEAMGREVNALK 451
Score = 36.3 bits (80), Expect = 0.37
Identities = 45/256 (17%), Positives = 103/256 (40%), Gaps = 10/256 (3%)
Query: 374 YNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRE 433
Y ++D + + L A ++E D + + + ++ L + + ++KD RE
Sbjct: 127 YETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRE 186
Query: 434 LDE----KESILETKQCVQKELESTKTDLEHRKTEIEEYKRLL----FEKGEEIDELKSK 485
L++ ++ I T + +K+ +S + DL + ++ +R EK E +EL S
Sbjct: 187 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASS 246
Query: 486 LSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFG 545
LS A++D +++ ++ L N++ R
Sbjct: 247 LSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERS-T 305
Query: 546 AFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQ-EHVLNKKEK 604
A N + + Q ++ +L + + K ++ ++ + + EQ E +K+
Sbjct: 306 AQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQA 365
Query: 605 EIKMLNEKEEEHMNII 620
K L +K+++ I+
Sbjct: 366 ATKSLKQKDKKLKEIL 381
>AM177179-1|CAJ45483.1| 1621|Homo sapiens kinesin-like protein
KIF21A variant protein.
Length = 1621
Score = 46.0 bits (104), Expect = 5e-04
Identities = 48/195 (24%), Positives = 85/195 (43%), Gaps = 12/195 (6%)
Query: 429 DLVRELDEKESILETKQCVQKELESTKTDLEHR-KTEIEEYKRLLFEKGEEIDELKSKLS 487
D +E E++ + E ++ + E+E ++ +H + E EE + + GE DE S+ S
Sbjct: 567 DTDQEKKEEKGVSE-RENNELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSE-S 624
Query: 488 TEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEE-LMNLKNQI--TQLREF 544
EKA R +K YEE LM L+++I TQL
Sbjct: 625 DEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERD 684
Query: 545 GAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEK 604
NL V + ++ K+ + EY++KLQ E++RL + E +L + +
Sbjct: 685 QVLQNLGSVESYSEEKAKKV------RSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQ 738
Query: 605 EIKMLNEKEEEHMNI 619
K L + +++ M +
Sbjct: 739 YEKQLKKLQQDVMEM 753
>AK021596-1|BAB13850.1| 619|Homo sapiens protein ( Homo sapiens
cDNA FLJ11534 fis, clone HEMBA1002679. ).
Length = 619
Score = 46.0 bits (104), Expect = 5e-04
Identities = 62/384 (16%), Positives = 152/384 (39%), Gaps = 25/384 (6%)
Query: 110 GGEPKALEHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGIST 169
G PK H K TF N + K T + ++++ +Q+ +
Sbjct: 242 GKTPKDYFHDKNAKKPTFQKK------NCKMQKSSHTAVPTRVNREKYKNITAQKSSSNI 295
Query: 170 KTLTMKIKEFNAENDLLKSSLD--QLRTEFLKEINDIIDCLRKNANETMALQLRT-KELS 226
L +I +N +L+++ +L + KE+N+ + ++ +++ +T K+L+
Sbjct: 296 ILLRERIISLQQQNSVLQNAKKAAELSVKEYKEVNEKLLHQQQVSDQRFQTSRQTIKKLN 355
Query: 227 CALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQL 286
L+ L + ++ K++ S A N M + + +++L
Sbjct: 356 LDLAGLRKEKEDLLKKLESSSEITSLAEENSQVTFPRIQVTSLSPSRSMDLEMKQLQYKL 415
Query: 287 KTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHL 346
K + + + ++ + E + E + ++ ++++++ + I +
Sbjct: 416 KNATNELTKQSSNVKTLKFELLAKEEHI-----------KEMHEKISRMERDITMKRHLI 464
Query: 347 EDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEK 406
ED+ R+K+ + +K +K + E + + ++++ N +++EK
Sbjct: 465 EDLKF-RQKVNLESNKSFSEMLQ---NLDKKVKTLTEECSNKKVSIDSLKQRLNVAVKEK 520
Query: 407 KTLQENIDDLRTDLLESELRVKDLVRELDEKESIL-ETKQCVQKELESTKTDLEHRKTEI 465
++ + +L + +L++ LV + E ES++ E + K+L+ E
Sbjct: 521 SQYEQMYQKSKEELEKKDLKLTLLVSRISETESVMAEIETAASKQLQELALQSEQVLEGA 580
Query: 466 EEYKRLLFEKGEEIDELKSKLSTE 489
++ L EK EE L+ E
Sbjct: 581 QKTLLLANEKVEEFTTFVKALAKE 604
>AB051495-1|BAB21799.2| 1657|Homo sapiens KIAA1708 protein.
Length = 1657
Score = 46.0 bits (104), Expect = 5e-04
Identities = 48/195 (24%), Positives = 85/195 (43%), Gaps = 12/195 (6%)
Query: 429 DLVRELDEKESILETKQCVQKELESTKTDLEHR-KTEIEEYKRLLFEKGEEIDELKSKLS 487
D +E E++ + E ++ + E+E ++ +H + E EE + + GE DE S+ S
Sbjct: 563 DTDQEKKEEKGVSE-RENNELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSE-S 620
Query: 488 TEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEE-LMNLKNQI--TQLREF 544
EKA R +K YEE LM L+++I TQL
Sbjct: 621 DEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERD 680
Query: 545 GAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEK 604
NL V + ++ K+ + EY++KLQ E++RL + E +L + +
Sbjct: 681 QVLQNLGSVESYSEEKAKKV------RSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQ 734
Query: 605 EIKMLNEKEEEHMNI 619
K L + +++ M +
Sbjct: 735 YEKQLKKLQQDVMEM 749
>BC057235-1|AAH57235.1| 613|Homo sapiens HMMR protein protein.
Length = 613
Score = 45.6 bits (103), Expect = 6e-04
Identities = 78/390 (20%), Positives = 168/390 (43%), Gaps = 27/390 (6%)
Query: 283 EHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNK----LTQS 338
E + NV++ L A+ + +S S S R + +D + EL K L +
Sbjct: 49 ESKQNLNVDKDTTLPASARKVKS-SESKIRVLLQERGAQDRRIQDLETELEKMEARLNAA 107
Query: 339 IKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLI-EIEK 397
+++ T+ + A ++L S + N+ K+++ ++L + KL + E
Sbjct: 108 LREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQ--KNLRI-LSLELMKLRNKRET 164
Query: 398 KYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD--EKESI---LETKQCVQ--KE 450
K + +++ ++ + + L ES+ ++ L +L EKE I ET++ ++ +E
Sbjct: 165 KMRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEE 224
Query: 451 LESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXX 510
+ +E K +I + + L EK +EI LK L E+ I +
Sbjct: 225 ISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSL--EENIVILSKQVEDLNVKCQLLE 282
Query: 511 XXXXXXXXXRESQMKSYYEELMNLKNQ-ITQLREFGAFDNLN-DVGNMINQQRDKLFELT 568
++ E+ NLK + I + +E + +++ Q+++ L
Sbjct: 283 KEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLH 342
Query: 569 KR----QEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLH 624
++ QEE ++ E E+K+ ++ + + + + E+ +K L E+ + + LL
Sbjct: 343 QKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLE 402
Query: 625 NKLELRNEADIDVIITLAKYKKSLTLVLEK 654
KL+ EA+++ + A + ++ L+ EK
Sbjct: 403 EKLK-GKEAELEK--SSAAHTQATLLLQEK 429
Score = 43.6 bits (98), Expect = 0.002
Identities = 73/345 (21%), Positives = 136/345 (39%), Gaps = 30/345 (8%)
Query: 277 DRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLT 336
+ +S A Q++ + QLE L++ E SL++++ ED + + L
Sbjct: 223 EEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLE 282
Query: 337 QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIE 396
+ +D+ R + + + ++ + L I L++ E
Sbjct: 283 KEKEDHVN--------RNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQE 334
Query: 397 KKYNDSIEEKK-TLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTK 455
K+ + S+ +K + QE + +L E EL K + ELD+ + E + + K+LE
Sbjct: 335 KELSSSLHQKLCSFQEEMVK-EKNLFEEEL--KQTLDELDKLQQKEEQAERLVKQLE--- 388
Query: 456 TDLEHRKTEIEEYKRLLFE--KGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXX 513
E K+ EE K LL E KG+E + KS + +A +
Sbjct: 389 ---EEAKSRAEELK-LLEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQF 444
Query: 514 XXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEE 573
S++ E + L+N Q + A N DV + I E + +
Sbjct: 445 ESYKALTASEI-----EDLKLENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLD 499
Query: 574 YDEKLQTKENEIKRL----VESMTEQEHVLNKKEKEIKMLNEKEE 614
K KE EIK + ++ +T+ ++ L ++E++ + E EE
Sbjct: 500 LQTKSALKETEIKEITVSFLQKITDLQNQLKQQEEDFRKQLEDEE 544
Score = 37.5 bits (83), Expect = 0.16
Identities = 66/303 (21%), Positives = 126/303 (41%), Gaps = 36/303 (11%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLR--TDLLES-ELRVKDLVR 432
+S+++ + ++ KL+ IEK+ D E + L E I+++ +D +E +L + L
Sbjct: 185 RSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEE 244
Query: 433 ELDEK-ESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
L EK + IL KQ +++ + +E + + L EK +E +++ E
Sbjct: 245 NLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQ-----LLEKEKEDHVNRNREHNENL 299
Query: 492 IKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLN 551
++ +E Q+ S ++ L + + Q + +F
Sbjct: 300 NAEMQNLKQKFILEQQEREKLQQ-----KELQIDSLLQQEKELSSSLHQ--KLCSFQE-- 350
Query: 552 DVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNE 611
M+ ++ EL + +E D KLQ KE + +RLV+ + E+ + +E+K+L E
Sbjct: 351 ---EMVKEKNLFEEELKQTLDELD-KLQQKEEQAERLVKQLEEE---AKSRAEELKLLEE 403
Query: 612 ----KEEE-------HMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNR 660
KE E H LL K + ++ DV YK +E + + N
Sbjct: 404 KLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLENS 463
Query: 661 VLK 663
L+
Sbjct: 464 SLQ 466
>BC011615-1|AAH11615.2| 739|Homo sapiens AZI1 protein protein.
Length = 739
Score = 45.6 bits (103), Expect = 6e-04
Identities = 72/364 (19%), Positives = 151/364 (41%), Gaps = 30/364 (8%)
Query: 277 DRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLT 336
+R+++A+ Q + ++++ +L +A E+AR E W E+T + E+ KL
Sbjct: 320 ERVAQAQAQHELEIKKLKELMSATEKARREKWISEKT----KKIKEVTVRGLEPEIQKLI 375
Query: 337 QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIE 396
K L+ + A E LQS S + ++++ ++ L + E
Sbjct: 376 ARHKQEVRRLKSLHEA-ELLQSDERA--------SQRCLRQAEELREQLEREKEALGQQE 426
Query: 397 KKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKT 456
++ ++ Q++++ + L + R+ V E E+E + + + ELE +
Sbjct: 427 RE-----RARQRFQQHLEQEQWALQQQRQRLYSEVAE--ERERLGQQAARQRAELEELRQ 479
Query: 457 DLEHRKTEIEEYKRLLFEKGEEIDELK--SKLSTEKAIKDIXXXXXXXXXXXXXXXXXXX 514
LE + + R FEKG E E + +L+T K ++
Sbjct: 480 QLEESSSALTRALRAEFEKGREEQERRHQMELNTLKQQLELERQAWEAGRTRKEEAWLLN 539
Query: 515 XXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEY 574
RE K +E+ + +++ ++ + I + RDK E+
Sbjct: 540 REQELREEIRKGRDKEIELVIHRLEADMALAKEESEKAAESRIKRLRDKYEAELSELEQS 599
Query: 575 DEKLQTKENEIK-RLVESMTEQ---EHVLNKKEK---EIKMLNEK-EEEHMNIINLLHNK 626
+ KLQ + +E+K +L E+ E + ++ +KE+ + + +NE+ E N+ ++ +
Sbjct: 600 ERKLQERCSELKGQLGEAEGENLRLQGLVRQKERALEDAQAVNEQLSSERSNLAQVIRQE 659
Query: 627 LELR 630
E R
Sbjct: 660 FEDR 663
Score = 39.1 bits (87), Expect = 0.053
Identities = 30/99 (30%), Positives = 56/99 (56%), Gaps = 8/99 (8%)
Query: 396 EKKYNDSIEEKKTLQENIDDLRTDLLESE---LRVKDLVRELDEKESILETKQCVQKELE 452
E + ++ + ++ LQE +L+ L E+E LR++ LVR+ KE LE Q V ++L
Sbjct: 590 EAELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQ---KERALEDAQAVNEQLS 646
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
S +++L + +E++ L EE + K++L+T +A
Sbjct: 647 SERSNL--AQVIRQEFEDRLAASEEETRQAKAELATLQA 683
Score = 37.9 bits (84), Expect = 0.12
Identities = 48/237 (20%), Positives = 96/237 (40%), Gaps = 12/237 (5%)
Query: 403 IEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRK 462
IE+KK L E + + +L + + R + V + + LE K+ KEL S K
Sbjct: 294 IEDKKVLSEKCEAVVAELKQEDQRCTERVAQAQAQHE-LEIKKL--KELMSATEKARREK 350
Query: 463 TEIEEYKRL--LFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXR 520
E+ K++ + +G E E++ ++ K +++ +
Sbjct: 351 WISEKTKKIKEVTVRGLE-PEIQKLIARHK--QEVRRLKSLHEAELLQSDERASQRCLRQ 407
Query: 521 ESQMKSYYEELMNLKNQITQLREFGAFD-NLNDVGNMINQQRDKLF-ELTKRQEEYDEKL 578
+++ E Q + R F +L + QQR +L+ E+ + +E ++
Sbjct: 408 AEELREQLEREKEALGQQERERARQRFQQHLEQEQWALQQQRQRLYSEVAEERERLGQQA 467
Query: 579 QTKENEIKRLVESMTEQEHVLNK--KEKEIKMLNEKEEEHMNIINLLHNKLELRNEA 633
+ E++ L + + E L + + + K E+E H +N L +LEL +A
Sbjct: 468 ARQRAELEELRQQLEESSSALTRALRAEFEKGREEQERRHQMELNTLKQQLELERQA 524
>BC006984-1|AAH06984.1| 512|Homo sapiens Unknown (protein for
IMAGE:3997460) protein.
Length = 512
Score = 45.6 bits (103), Expect = 6e-04
Identities = 78/390 (20%), Positives = 168/390 (43%), Gaps = 27/390 (6%)
Query: 283 EHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNK----LTQS 338
E + NV++ L A+ + +S S S R + +D + EL K L +
Sbjct: 49 ESKQNLNVDKDTTLPASARKVKS-SESKIRVLLQERGAQDRRIQDLETELEKMEARLNAA 107
Query: 339 IKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLI-EIEK 397
+++ T+ + A ++L S + N+ K+++ ++L + KL + E
Sbjct: 108 LREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQ--KNLRI-LSLELMKLRNKRET 164
Query: 398 KYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELD--EKESI---LETKQCVQ--KE 450
K + +++ ++ + + L ES+ ++ L +L EKE I ET++ ++ +E
Sbjct: 165 KMRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEEIDEKSETEKLLEYIEE 224
Query: 451 LESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXX 510
+ +E K +I + + L EK +EI LK L E+ I +
Sbjct: 225 ISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSL--EENIVILSKQVEDLNVKCQLLE 282
Query: 511 XXXXXXXXXRESQMKSYYEELMNLKNQ-ITQLREFGAFDNLN-DVGNMINQQRDKLFELT 568
++ E+ NLK + I + +E + +++ Q+++ L
Sbjct: 283 KEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLH 342
Query: 569 KR----QEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLH 624
++ QEE ++ E E+K+ ++ + + + + E+ +K L E+ + + LL
Sbjct: 343 QKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLE 402
Query: 625 NKLELRNEADIDVIITLAKYKKSLTLVLEK 654
KL+ EA+++ + A + ++ L+ EK
Sbjct: 403 EKLK-GKEAELEK--SSAAHTQATLLLQEK 429
Score = 37.5 bits (83), Expect = 0.16
Identities = 66/303 (21%), Positives = 126/303 (41%), Gaps = 36/303 (11%)
Query: 376 KSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLR--TDLLES-ELRVKDLVR 432
+S+++ + ++ KL+ IEK+ D E + L E I+++ +D +E +L + L
Sbjct: 185 RSLEESQGKIAQLEGKLVSIEKEEIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEE 244
Query: 433 ELDEK-ESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
L EK + IL KQ +++ + +E + + L EK +E +++ E
Sbjct: 245 NLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQ-----LLEKEKEDHVNRNREHNENL 299
Query: 492 IKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLN 551
++ +E Q+ S ++ L + + Q + +F
Sbjct: 300 NAEMQNLKQKFILEQQEREKLQQ-----KELQIDSLLQQEKELSSSLHQ--KLCSFQE-- 350
Query: 552 DVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNE 611
M+ ++ EL + +E D KLQ KE + +RLV+ + E+ + +E+K+L E
Sbjct: 351 ---EMVKEKNLFEEELKQTLDELD-KLQQKEEQAERLVKQLEEE---AKSRAEELKLLEE 403
Query: 612 ----KEEE-------HMNIINLLHNKLELRNEADIDVIITLAKYKKSLTLVLEKMSISNR 660
KE E H LL K + ++ DV YK +E + + N
Sbjct: 404 KLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLENS 463
Query: 661 VLK 663
L+
Sbjct: 464 SLQ 466
Score = 33.9 bits (74), Expect = 2.0
Identities = 50/218 (22%), Positives = 92/218 (42%), Gaps = 21/218 (9%)
Query: 277 DRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLT 336
+ +S A Q++ + QLE L++ E SL++++ ED + + L
Sbjct: 223 EEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLE 282
Query: 337 QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIE 396
+ +D+ R + + + ++ + L I L++ E
Sbjct: 283 KEKEDHVN--------RNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQE 334
Query: 397 KKYNDSIEEKK-TLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTK 455
K+ + S+ +K + QE + +L E EL K + ELD+ + E + + K+LE
Sbjct: 335 KELSSSLHQKLCSFQEEMVK-EKNLFEEEL--KQTLDELDKLQQKEEQAERLVKQLE--- 388
Query: 456 TDLEHRKTEIEEYKRLLFE--KGEEIDELKSKLSTEKA 491
E K+ EE K LL E KG+E + KS + +A
Sbjct: 389 ---EEAKSRAEELK-LLEEKLKGKEAELEKSSAAHTQA 422
>AY237536-1|AAP04413.1| 1401|Homo sapiens KIF27A protein.
Length = 1401
Score = 45.6 bits (103), Expect = 6e-04
Identities = 55/259 (21%), Positives = 109/259 (42%), Gaps = 13/259 (5%)
Query: 379 KDMKHEMNLNIAKLI-EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEK 437
K + + +L + KL + E+ + IE +K LQE + +D+ K+ +++D
Sbjct: 751 KSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQELENKDLSDVAMKVKLQKEFRKKMDAA 810
Query: 438 E---SILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKD 494
+ +L+ KQ K+L S E R E+E+ + K ++I +L+ KL E +
Sbjct: 811 KLRVQVLQKKQQDSKKLASLSIQNEKRANELEQSVDHM--KYQKI-QLQRKLREENEKRK 867
Query: 495 IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEEL--MNLKNQITQLREFGAFDNLND 552
+E +K E+L NLK + L++
Sbjct: 868 ----QLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDLDACNLKRRKGSFGSIDHLQKLDE 923
Query: 553 VGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEK 612
++++ +K+ + EE + L+ +E + + + E+ H+ NKK + + LN
Sbjct: 924 QKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKEALLQEKSHLENKKLRSSQALNTD 983
Query: 613 EEEHMNIINLLHNKLELRN 631
+ +NLL +L +N
Sbjct: 984 SLKISTRLNLLEQELSEKN 1002
>AL354733-4|CAI16013.1| 1401|Homo sapiens kinesin family member 27
protein.
Length = 1401
Score = 45.6 bits (103), Expect = 6e-04
Identities = 55/259 (21%), Positives = 109/259 (42%), Gaps = 13/259 (5%)
Query: 379 KDMKHEMNLNIAKLI-EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEK 437
K + + +L + KL + E+ + IE +K LQE + +D+ K+ +++D
Sbjct: 751 KSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQELENKDLSDVAMKVKLQKEFRKKMDAA 810
Query: 438 E---SILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKD 494
+ +L+ KQ K+L S E R E+E+ + K ++I +L+ KL E +
Sbjct: 811 KLRVQVLQKKQQDSKKLASLSIQNEKRANELEQSVDHM--KYQKI-QLQRKLREENEKRK 867
Query: 495 IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEEL--MNLKNQITQLREFGAFDNLND 552
+E +K E+L NLK + L++
Sbjct: 868 ----QLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDLDACNLKRRKGSFGSIDHLQKLDE 923
Query: 553 VGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEK 612
++++ +K+ + EE + L+ +E + + + E+ H+ NKK + + LN
Sbjct: 924 QKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKEALLQEKSHLENKKLRSSQALNTD 983
Query: 613 EEEHMNIINLLHNKLELRN 631
+ +NLL +L +N
Sbjct: 984 SLKISTRLNLLEQELSEKN 1002
>AL133654-1|CAB63770.1| 833|Homo sapiens hypothetical protein
protein.
Length = 833
Score = 45.6 bits (103), Expect = 6e-04
Identities = 55/259 (21%), Positives = 109/259 (42%), Gaps = 13/259 (5%)
Query: 379 KDMKHEMNLNIAKLI-EIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEK 437
K + + +L + KL + E+ + IE +K LQE + +D+ K+ +++D
Sbjct: 183 KSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQELENKDLSDVAMKVKLQKEFRKKMDAA 242
Query: 438 E---SILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKD 494
+ +L+ KQ K+L S E R E+E+ + K ++I +L+ KL E +
Sbjct: 243 KLRVQVLQKKQQDSKKLASLSIQNEKRANELEQSVDHM--KYQKI-QLQRKLREENEKRK 299
Query: 495 IXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEEL--MNLKNQITQLREFGAFDNLND 552
+E +K E+L NLK + L++
Sbjct: 300 ----QLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDLDACNLKRRKGSFGSIDHLQKLDE 355
Query: 553 VGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEK 612
++++ +K+ + EE + L+ +E + + + E+ H+ NKK + + LN
Sbjct: 356 QKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKEALLQEKSHLENKKLRSSQALNTD 415
Query: 613 EEEHMNIINLLHNKLELRN 631
+ +NLL +L +N
Sbjct: 416 SLKISTRLNLLEQELSEKN 434
Score = 31.9 bits (69), Expect = 8.0
Identities = 50/236 (21%), Positives = 103/236 (43%), Gaps = 25/236 (10%)
Query: 393 IEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELE 452
I++++K + E++K L I + + E +L+ +E K + C K +
Sbjct: 285 IQLQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTG---QEEGLKPKAEDLDACNLKRRK 341
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGE-------EIDELKSKLSTEKAI---KDIXXXXXXX 502
+ ++H + +++E K+ L E+ E E++EL++ L +AI K+
Sbjct: 342 GSFGSIDHLQ-KLDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKEALLQEKSH 400
Query: 503 XXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRD 562
+ S + E+ ++ KN Q +++ ++ +++D
Sbjct: 401 LENKKLRSSQALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQVEVLQKEKD 460
Query: 563 KLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMN 618
+L KR+ + DEKL+ R++ E+EHVL + E+ I+ L E E+ N
Sbjct: 461 ---QLQKRRHDVDEKLKNG-----RVLSP--EEEHVLFQLEEGIEAL-EAAIEYRN 505
>AB029041-1|BAA83070.1| 1165|Homo sapiens KIAA1118 protein protein.
Length = 1165
Score = 45.6 bits (103), Expect = 6e-04
Identities = 72/364 (19%), Positives = 151/364 (41%), Gaps = 30/364 (8%)
Query: 277 DRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLT 336
+R+++A+ Q + ++++ +L +A E+AR E W E+T + E+ KL
Sbjct: 746 ERVAQAQAQHELEIKKLKELMSATEKARREKWISEKT----KKIKEVTVRGLEPEIQKLI 801
Query: 337 QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIE 396
K L+ + A E LQS S + ++++ ++ L + E
Sbjct: 802 ARHKQEVRRLKSLHEA-ELLQSDERA--------SQRCLRQAEELREQLEREKEALGQQE 852
Query: 397 KKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKT 456
++ ++ Q++++ + L + R+ V E E+E + + + ELE +
Sbjct: 853 RE-----RARQRFQQHLEQEQWALQQQRQRLYSEVAE--ERERLGQQAARQRAELEELRQ 905
Query: 457 DLEHRKTEIEEYKRLLFEKGEEIDELK--SKLSTEKAIKDIXXXXXXXXXXXXXXXXXXX 514
LE + + R FEKG E E + +L+T K ++
Sbjct: 906 QLEESSSALTRALRAEFEKGREEQERRHQMELNTLKQQLELERQAWEAGRTRKEEAWLLN 965
Query: 515 XXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEY 574
RE K +E+ + +++ ++ + I + RDK E+
Sbjct: 966 REQELREEIRKGRDKEIELVIHRLEADMALAKEESEKAAESRIKRLRDKYEAELSELEQS 1025
Query: 575 DEKLQTKENEIK-RLVESMTEQ---EHVLNKKEK---EIKMLNEK-EEEHMNIINLLHNK 626
+ KLQ + +E+K +L E+ E + ++ +KE+ + + +NE+ E N+ ++ +
Sbjct: 1026 ERKLQERCSELKGQLGEAEGENLRLQGLVRQKERALEDAQAVNEQLSSERSNLAQVIRQE 1085
Query: 627 LELR 630
E R
Sbjct: 1086 FEDR 1089
Score = 39.1 bits (87), Expect = 0.053
Identities = 30/99 (30%), Positives = 56/99 (56%), Gaps = 8/99 (8%)
Query: 396 EKKYNDSIEEKKTLQENIDDLRTDLLESE---LRVKDLVRELDEKESILETKQCVQKELE 452
E + ++ + ++ LQE +L+ L E+E LR++ LVR+ KE LE Q V ++L
Sbjct: 1016 EAELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQ---KERALEDAQAVNEQLS 1072
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
S +++L + +E++ L EE + K++L+T +A
Sbjct: 1073 SERSNL--AQVIRQEFEDRLAASEEETRQAKAELATLQA 1109
Score = 37.9 bits (84), Expect = 0.12
Identities = 48/237 (20%), Positives = 96/237 (40%), Gaps = 12/237 (5%)
Query: 403 IEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRK 462
IE+KK L E + + +L + + R + V + + LE K+ KEL S K
Sbjct: 720 IEDKKVLSEKCEAVVAELKQEDQRCTERVAQAQAQHE-LEIKKL--KELMSATEKARREK 776
Query: 463 TEIEEYKRL--LFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXR 520
E+ K++ + +G E E++ ++ K +++ +
Sbjct: 777 WISEKTKKIKEVTVRGLE-PEIQKLIARHK--QEVRRLKSLHEAELLQSDERASQRCLRQ 833
Query: 521 ESQMKSYYEELMNLKNQITQLREFGAFD-NLNDVGNMINQQRDKLF-ELTKRQEEYDEKL 578
+++ E Q + R F +L + QQR +L+ E+ + +E ++
Sbjct: 834 AEELREQLEREKEALGQQERERARQRFQQHLEQEQWALQQQRQRLYSEVAEERERLGQQA 893
Query: 579 QTKENEIKRLVESMTEQEHVLNK--KEKEIKMLNEKEEEHMNIINLLHNKLELRNEA 633
+ E++ L + + E L + + + K E+E H +N L +LEL +A
Sbjct: 894 ARQRAELEELRQQLEESSSALTRALRAEFEKGREEQERRHQMELNTLKQQLELERQA 950
>Z11584-1|CAA77670.1| 2101|Homo sapiens NuMA protein protein.
Length = 2101
Score = 45.2 bits (102), Expect = 8e-04
Identities = 73/379 (19%), Positives = 150/379 (39%), Gaps = 29/379 (7%)
Query: 277 DRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLT 336
DRL+ + + +LE ++ S + L T+ + D+++N+L+
Sbjct: 259 DRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQDLKTEKSQ-MDRKINQLS 317
Query: 337 QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIE 396
+ D + L + A ++LQ + + + ++ E++ + +E
Sbjct: 318 EENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLE 377
Query: 397 KKYNDSIEEKKT-LQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTK 455
+K N+ ++ K + L+E++ L+ + + + V V +L+ + T +L++
Sbjct: 378 EK-NEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARV 436
Query: 456 TDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXX 515
LE + + E +LL E+G +E K +LS+ I D+
Sbjct: 437 EMLETERGQQEA--KLLAERGH-FEEEKQQLSS--LITDLQSSISNLSQAKEELEQASQA 491
Query: 516 XXXXRESQMKSYYEELMNLKNQITQL-REFG-----AFDNLNDVGNMINQQRDKLFELTK 569
+Q+ S EL L I Q +E A + + + QQ L
Sbjct: 492 HGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRH 551
Query: 570 RQEEYDEKLQTKENEIKRLVESM--TEQEHV-------------LNKKEKEIKMLNEKEE 614
+ E+ L+ KE ++K + E T Q+H L +++ +K L E+
Sbjct: 552 QVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEK 611
Query: 615 EHMNIINLLHNKLELRNEA 633
E + +L +L++ NEA
Sbjct: 612 EKAAKLEILQQQLQVANEA 630
Score = 41.9 bits (94), Expect = 0.007
Identities = 65/357 (18%), Positives = 137/357 (38%), Gaps = 15/357 (4%)
Query: 147 LFKRKEIINWFESLMSQEKG------ISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKE 200
L + +E ++ + QEKG + +TL + A N L++ ++ L TE ++
Sbjct: 387 LSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQ 446
Query: 201 INDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRK--QIHSGDHHRPYAN-RNX 257
++ E L +L ++S+L+ E+ + Q H A+ +
Sbjct: 447 EAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSE 506
Query: 258 XXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAAL----EQARSESWSLERT 313
+ +K + + QL +++ Q L EQ S E+
Sbjct: 507 LTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQ 566
Query: 314 VXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAR-EKLQSXXXXXXXXXXXXSA 372
+ +D Q+L + ++ + D AL + E L+
Sbjct: 567 LKEVAEKQEATRQDHAQQLATAAEE-REASLRERDAALKQLEALEKEKAAKLEILQQQLQ 625
Query: 373 SYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVR 432
N++ + + + E+ +K + +T ++ + + + E EL+++ +
Sbjct: 626 VANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQ 685
Query: 433 ELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
+ EKE + + K +Q++L++ K L+ K +EE KR + EE S+L E
Sbjct: 686 KATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAE 742
Score = 37.1 bits (82), Expect = 0.21
Identities = 44/216 (20%), Positives = 90/216 (41%), Gaps = 9/216 (4%)
Query: 281 RAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIK 340
RA+ L +LE L+ A +E T+ E DQEL KL
Sbjct: 1015 RAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEA 1074
Query: 341 DNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKS---IKDMKHEMNLNIAKLIEIEK 397
LE++ ++L+ S + +++ + ++ A++ ++E+
Sbjct: 1075 AQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQ 1134
Query: 398 KYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQ----CVQKELES 453
+ E+ +L+ +++ R E + ++ L +L+EK L Q Q+EL +
Sbjct: 1135 QCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAA 1194
Query: 454 TKTDL-EHRKTEIEEYKRLLFEKGEEIDELKSKLST 488
+T + +H K E +E+K + +E + S +S+
Sbjct: 1195 FRTKVQDHSKAE-DEWKAQVARGRQEAERKNSLISS 1229
Score = 34.3 bits (75), Expect = 1.5
Identities = 22/113 (19%), Positives = 53/113 (46%), Gaps = 2/113 (1%)
Query: 375 NKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVREL 434
+K + D + KL ++ + +S +E + Q +++L+ L + E + ++
Sbjct: 1541 SKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRFQAQLNELQAQLSQKEQAAEHYKLQM 1600
Query: 435 DEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE--LKSK 485
++ ++ + K+ +EL+ LE + E +E + G E+ + LK+K
Sbjct: 1601 EKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTK 1653
Score = 32.7 bits (71), Expect = 4.6
Identities = 31/121 (25%), Positives = 56/121 (46%), Gaps = 4/121 (3%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRV--KD 429
A ++ + ++ E +L ++K + EE + L E + L LE EL +
Sbjct: 1417 AEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERAN-LGRQFLEVELDQAREK 1475
Query: 430 LVRELDEKESILETKQC-VQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLST 488
V+EL + ET+ VQ+E +ST +LE + E K + E+ + E + KL+
Sbjct: 1476 YVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLTA 1535
Query: 489 E 489
+
Sbjct: 1536 Q 1536
>Z11583-1|CAA77669.1| 2115|Homo sapiens NuMA protein protein.
Length = 2115
Score = 45.2 bits (102), Expect = 8e-04
Identities = 73/379 (19%), Positives = 150/379 (39%), Gaps = 29/379 (7%)
Query: 277 DRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLT 336
DRL+ + + +LE ++ S + L T+ + D+++N+L+
Sbjct: 259 DRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQDLKTEKSQ-MDRKINQLS 317
Query: 337 QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIE 396
+ D + L + A ++LQ + + + ++ E++ + +E
Sbjct: 318 EENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLE 377
Query: 397 KKYNDSIEEKKT-LQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTK 455
+K N+ ++ K + L+E++ L+ + + + V V +L+ + T +L++
Sbjct: 378 EK-NEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARV 436
Query: 456 TDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXX 515
LE + + E +LL E+G +E K +LS+ I D+
Sbjct: 437 EMLETERGQQEA--KLLAERGH-FEEEKQQLSS--LITDLQSSISNLSQAKEELEQASQA 491
Query: 516 XXXXRESQMKSYYEELMNLKNQITQL-REFG-----AFDNLNDVGNMINQQRDKLFELTK 569
+Q+ S EL L I Q +E A + + + QQ L
Sbjct: 492 HGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRH 551
Query: 570 RQEEYDEKLQTKENEIKRLVESM--TEQEHV-------------LNKKEKEIKMLNEKEE 614
+ E+ L+ KE ++K + E T Q+H L +++ +K L E+
Sbjct: 552 QVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEK 611
Query: 615 EHMNIINLLHNKLELRNEA 633
E + +L +L++ NEA
Sbjct: 612 EKAAKLEILQQQLQVANEA 630
Score = 41.9 bits (94), Expect = 0.007
Identities = 65/357 (18%), Positives = 137/357 (38%), Gaps = 15/357 (4%)
Query: 147 LFKRKEIINWFESLMSQEKG------ISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKE 200
L + +E ++ + QEKG + +TL + A N L++ ++ L TE ++
Sbjct: 387 LSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQ 446
Query: 201 INDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRK--QIHSGDHHRPYAN-RNX 257
++ E L +L ++S+L+ E+ + Q H A+ +
Sbjct: 447 EAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSE 506
Query: 258 XXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAAL----EQARSESWSLERT 313
+ +K + + QL +++ Q L EQ S E+
Sbjct: 507 LTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQ 566
Query: 314 VXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAR-EKLQSXXXXXXXXXXXXSA 372
+ +D Q+L + ++ + D AL + E L+
Sbjct: 567 LKEVAEKQEATRQDHAQQLATAAEE-REASLRERDAALKQLEALEKEKAAKLEILQQQLQ 625
Query: 373 SYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVR 432
N++ + + + E+ +K + +T ++ + + + E EL+++ +
Sbjct: 626 VANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQ 685
Query: 433 ELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
+ EKE + + K +Q++L++ K L+ K +EE KR + EE S+L E
Sbjct: 686 KATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAE 742
Score = 37.1 bits (82), Expect = 0.21
Identities = 44/216 (20%), Positives = 90/216 (41%), Gaps = 9/216 (4%)
Query: 281 RAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIK 340
RA+ L +LE L+ A +E T+ E DQEL KL
Sbjct: 1015 RAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEA 1074
Query: 341 DNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKS---IKDMKHEMNLNIAKLIEIEK 397
LE++ ++L+ S + +++ + ++ A++ ++E+
Sbjct: 1075 AQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQ 1134
Query: 398 KYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQ----CVQKELES 453
+ E+ +L+ +++ R E + ++ L +L+EK L Q Q+EL +
Sbjct: 1135 QCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAA 1194
Query: 454 TKTDL-EHRKTEIEEYKRLLFEKGEEIDELKSKLST 488
+T + +H K E +E+K + +E + S +S+
Sbjct: 1195 FRTKVQDHSKAE-DEWKAQVARGRQEAERKNSLISS 1229
Score = 35.9 bits (79), Expect = 0.49
Identities = 23/113 (20%), Positives = 54/113 (47%), Gaps = 2/113 (1%)
Query: 375 NKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVREL 434
+K + D + KL ++ + +S +E + LQ +++L+ L + E + ++
Sbjct: 1555 SKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQM 1614
Query: 435 DEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE--LKSK 485
++ ++ + K+ +EL+ LE + E +E + G E+ + LK+K
Sbjct: 1615 EKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTK 1667
Score = 33.1 bits (72), Expect = 3.5
Identities = 46/245 (18%), Positives = 99/245 (40%), Gaps = 11/245 (4%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRV--KD 429
A ++ + ++ E +L ++K + EE + L E + L LE EL +
Sbjct: 1417 AEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERAN-LGRQFLEVELDQAREK 1475
Query: 430 LVRELDEKESILETKQC-VQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLST 488
V+EL + ET+ VQ+E +ST +LE + E K + E+ + E + KL+
Sbjct: 1476 YVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLTA 1535
Query: 489 E-KAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAF 547
+ + ++ ++ ++K+ + + + +L+
Sbjct: 1536 QVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQA---- 1591
Query: 548 DNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK 607
LN++ ++Q+ + E+ K+ + + L E + E L K+ KE++
Sbjct: 1592 -QLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQ-LQKENKELR 1649
Query: 608 MLNEK 612
E+
Sbjct: 1650 AEAER 1654
>U33822-1|AAC52059.1| 803|Homo sapiens TXBP181 protein.
Length = 803
Score = 45.2 bits (102), Expect = 8e-04
Identities = 46/230 (20%), Positives = 88/230 (38%), Gaps = 9/230 (3%)
Query: 373 SYNKSIKDMKHEMNLNIAKLIE----IEKKYNDSIEEKKTLQENIDDLRTDLLESELRVK 428
+Y + + D E+ I +L E E+K + +E + Q+N+D L E E +
Sbjct: 95 NYEREV-DRNQELLTRIRQLQEREAGAEEKMQEQLERNRQCQQNLDAASKRLREKEDSLA 153
Query: 429 DLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLST 488
++ + + Q + E LE K +++E L +K +E ++ +L
Sbjct: 154 QAGETINALKGRISELQWSVMDQEMRVKRLESEKQDVQEQLDLQHKKCQEANQKIQELQA 213
Query: 489 EKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFD 548
+ + MKS L L+ ++ QLRE A
Sbjct: 214 SQEAR----ADHEQQIKDLEQKLSLQEQDAAIVKNMKSELVRLPRLERELEQLREESALR 269
Query: 549 NLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHV 598
+ + ++ ++ + L RQE+ E L E E +RL+ + E +
Sbjct: 270 EMRETNGLLQEELEGLQRKLGRQEKMQETLVGLELENERLLAKLQSWERL 319
Score = 33.5 bits (73), Expect = 2.6
Identities = 26/115 (22%), Positives = 55/115 (47%), Gaps = 5/115 (4%)
Query: 521 ESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFEL---TKRQEEYDEK 577
+ Q++ + NL +LRE D+L G IN + ++ EL QE ++
Sbjct: 125 QEQLERNRQCQQNLDAASKRLRE--KEDSLAQAGETINALKGRISELQWSVMDQEMRVKR 182
Query: 578 LQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNE 632
L++++ +++ ++ ++ N+K +E++ E +H I L KL L+ +
Sbjct: 183 LESEKQDVQEQLDLQHKKCQEANQKIQELQASQEARADHEQQIKDLEQKLSLQEQ 237
>BC113409-1|AAI13410.1| 1416|Homo sapiens uveal autoantigen with
coiled-coil domains and ankyrin repeats protein.
Length = 1416
Score = 45.2 bits (102), Expect = 8e-04
Identities = 112/596 (18%), Positives = 230/596 (38%), Gaps = 44/596 (7%)
Query: 49 EKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVN---LPSAEELHIMNVAKLSPEQLL 105
++ + ++D + + +L LR ++ ++L KVN L EE+ + + + E+L
Sbjct: 290 QREHQNIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESEREKLK 349
Query: 106 QLCAGGEPKALEH----STLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIIN------ 155
L A E + E L N+ + + L + ++ E+ L K+ ++
Sbjct: 350 SLLAAKEKQHEESLRTIEALKNRFKYFESDHLGSGSHFSNRKEDMLLKQGQMYMADSQCT 409
Query: 156 --WFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNAN 213
+ M + L++ + +EN++LK L+ +RT F + D L K N
Sbjct: 410 SPGIPAHMQSRSMLRPLELSLPSQTSYSENEILKKELEAMRT-FCESAKQ--DRL-KLQN 465
Query: 214 ETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXS 273
E K L+ + + E KQ+
Sbjct: 466 ELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKE 525
Query: 274 IMKDRLSRAEHQLKTNV-ERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQEL 332
+ + H+L + +++ L+ E A +E L + E+F ++
Sbjct: 526 HLTSEAASGNHRLTEELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIV----EEFKRDE 581
Query: 333 NKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSI-----KDMK----H 383
KL + K L + REK SA SI ++MK +
Sbjct: 582 GKLIEENKRLQKELSMCEMEREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSN 641
Query: 384 EMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLES-ELRVKDLVRELDEKESILE 442
E+N KL+E+E+++ S+ E + L+ +++++ L + + + V+ E++S
Sbjct: 642 EVNEKAKKLVEMEREHEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGEL 701
Query: 443 TKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEID-ELKSKLSTEKAIKDIXXXXXX 501
K+ + L++ E K ++ +LL E+ + E+K+ K +D+
Sbjct: 702 GKKITELTLKNQTLQKEIEKVYLDN--KLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDA 759
Query: 502 XXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLND-----VGNM 556
++ +M+ E +L +++L ++ + +
Sbjct: 760 IIDDLNRKLLDVTQKYTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSN 819
Query: 557 INQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM-LNE 611
I + + +L EL K+ E EK+ +E L + M+ Q +V K +E+KM LN+
Sbjct: 820 IVELKKQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQ-YVPVKTHEEVKMTLND 874
Score = 40.3 bits (90), Expect = 0.023
Identities = 49/242 (20%), Positives = 104/242 (42%), Gaps = 13/242 (5%)
Query: 380 DMKHEMNLNIA-KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKE 438
+ HEM ++ K E+ K+ D + +K T +N+ + + + V+ L +K+
Sbjct: 1052 EKSHEMERALSRKTDELNKQLKD-LSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQ 1110
Query: 439 SI-LETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXX 497
+ LE + ++K L T +E+ K E++ +R ++ + + +L L +K
Sbjct: 1111 HVPLEQVEALKKSLNGT---IENLKEELKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLA 1167
Query: 498 XXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMI 557
+E + ++ EE+ L++++ ++ +V ++
Sbjct: 1168 EHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLETREVVDLS 1227
Query: 558 NQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHM 617
+ K +L + +EKL + R E + E+ VL+ K+KEI +EKE H
Sbjct: 1228 KYKATKS-DLETQISSLNEKLAN----LNRKYEEVCEE--VLHAKKKEISAKDEKELLHF 1280
Query: 618 NI 619
+I
Sbjct: 1281 SI 1282
Score = 39.9 bits (89), Expect = 0.030
Identities = 112/619 (18%), Positives = 254/619 (41%), Gaps = 78/619 (12%)
Query: 23 EQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQK 82
E E + E+ ++K + + V EK +KE+ ++ ++EL L +K +K
Sbjct: 781 EMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEK 840
Query: 83 VNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTL--DNKVTFDVNKLLNIPNSLV 140
++ ++E N+ K+ Q + + E K + TL N+ DV K N
Sbjct: 841 IHALTSENT---NLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEF 897
Query: 141 DKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKE 200
K ++ + EI+ +L + + I + +++ AE++ SSL Q +
Sbjct: 898 VKIKD----KNEILK--RNLENTQNQIKAEYISL------AEHEAKMSSLSQSMRKVQDS 945
Query: 201 INDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXX 260
+I+ RK E + L E+ +L+T ++ + + P +
Sbjct: 946 NAEILANYRKGQEEIVTLHA---EIKAQKKELDTIQECIKVK------YAPIVSFEECER 996
Query: 261 XXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXX 320
+KD+LS + + E V + + ++ + E ++L++ +
Sbjct: 997 KFKATEKE------LKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVL 1050
Query: 321 XXXXXE---DFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKS 377
E ++ ++L + +KD + ++ +EKL S +
Sbjct: 1051 IEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAK--------QTSEILA 1102
Query: 378 IKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEK 437
++++ + ++ + ++ ++K N +IE L+E + ++ + + V L + L+ +
Sbjct: 1103 VQNLLQKQHVPLEQVEALKKSLNGTIEN---LKEELKSMQRCYEKEQQTVTKLHQLLENQ 1159
Query: 438 ESI-------LETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKL-STE 489
++ L+ K+ +KE+ K L ++ E + K EE+ +L+S++ +T+
Sbjct: 1160 KNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQN-------KMEEVSKLQSEVQNTK 1212
Query: 490 KAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDN 549
+A+K + E+Q+ S E+L NL + ++ E +
Sbjct: 1213 QALKKLETREVVDLSKYKATKSDL-------ETQISSLNEKLANLNRKYEEVCE----EV 1261
Query: 550 LNDVGNMINQQRDK-LFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM 608
L+ I+ + +K L + QE D+K + ++ + ++TE + + + K+I+
Sbjct: 1262 LHAKKKEISAKDEKELLHFSIEQEIKDQKERCDKS-----LTTITELQRRIQESAKQIEA 1316
Query: 609 LNEKEEEHMNIINLLHNKL 627
+ K E +N + L L
Sbjct: 1317 KDNKITELLNDVERLKQAL 1335
Score = 38.7 bits (86), Expect = 0.070
Identities = 45/243 (18%), Positives = 106/243 (43%), Gaps = 15/243 (6%)
Query: 380 DMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKES 439
++ H++ A +E E+ DS E+ K L++ + D++ + ESE +VK + +
Sbjct: 466 ELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQM------QTH 519
Query: 440 ILETKQCVQKELESTKTDL-EHRKTEIEEYKRLLFEKGEEIDELKSKL-STEKAIKDIXX 497
L K+ + E S L E K ++++ K E+ +L++++ E +++
Sbjct: 520 FLALKEHLTSEAASGNHRLTEELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKR 579
Query: 498 XXXXXXXXXXXXXXXXXXXXXXRESQMKSYYE---ELMNLKNQITQLREFGAFDNL-NDV 553
RE + + E + L ++ F+N+ + +
Sbjct: 580 DEGKLIEENKRLQKELSMCEMEREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSL 639
Query: 554 GNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK-MLNEK 612
N +N++ KL E+ + E+ +++ + E++ + + +HV ++ +++K L +K
Sbjct: 640 SNEVNEKAKKLVEMEREHEKSLSEIRQLKRELENVKAKLA--QHVKPEEHEQVKSRLEQK 697
Query: 613 EEE 615
E
Sbjct: 698 SGE 700
Score = 37.9 bits (84), Expect = 0.12
Identities = 85/463 (18%), Positives = 171/463 (36%), Gaps = 30/463 (6%)
Query: 171 TLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALS 230
TL + + N E +K + + EF+K I D + L++N T Q++ + +S A
Sbjct: 871 TLNDTLAKTNRELLDVKKKFEDINQEFVK-IKDKNEILKRNLENTQN-QIKAEYISLAEH 928
Query: 231 DLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNV 290
+ + + + AN K L + +K
Sbjct: 929 EAKMSSLSQSMRKVQDSNAEILANYRKGQEEIVTLHAEIKA---QKKELDTIQECIKVKY 985
Query: 291 ERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFD---QELNKLTQSIKDNTTHLE 347
+V E + ++ L+ + E+ QE +KL + I L
Sbjct: 986 APIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLR 1045
Query: 348 DIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKK 407
D + EK NK +KD+ K E++ +EE
Sbjct: 1046 DKTVLIEKSHEMERALSRKTD----ELNKQLKDLSQ-------KYTEVKNVKEKLVEENA 1094
Query: 408 TLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEE 467
I ++ +LL+ + + V L K+S+ T + +++EL+S + E + + +
Sbjct: 1095 KQTSEILAVQ-NLLQKQHVPLEQVEAL--KKSLNGTIENLKEELKSMQRCYEKEQQTVTK 1151
Query: 468 YKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSY 527
+LL + L L ++A + +S++++
Sbjct: 1152 LHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNT 1211
Query: 528 YEELMNLKN-QITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEY-DEKLQTKENEI 585
+ L L+ ++ L ++ A +D+ I+ +KL L ++ EE +E L K+ EI
Sbjct: 1212 KQALKKLETREVVDLSKYKA--TKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEI 1269
Query: 586 KRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
+ E+E + E+EIK E+ ++ + I L +++
Sbjct: 1270 S----AKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQ 1308
>BC113407-1|AAI13408.1| 1416|Homo sapiens uveal autoantigen with
coiled-coil domains and ankyrin repeats protein.
Length = 1416
Score = 45.2 bits (102), Expect = 8e-04
Identities = 112/596 (18%), Positives = 230/596 (38%), Gaps = 44/596 (7%)
Query: 49 EKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVN---LPSAEELHIMNVAKLSPEQLL 105
++ + ++D + + +L LR ++ ++L KVN L EE+ + + + E+L
Sbjct: 290 QREHQNIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESEREKLK 349
Query: 106 QLCAGGEPKALEH----STLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIIN------ 155
L A E + E L N+ + + L + ++ E+ L K+ ++
Sbjct: 350 SLLAAKEKQHEESLRTIEALKNRFKYFESDHLGSGSHFSNRKEDMLLKQGQMYMADSQCT 409
Query: 156 --WFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNAN 213
+ M + L++ + +EN++LK L+ +RT F + D L K N
Sbjct: 410 SPGIPAHMQSRSMLRPLELSLPSQTSYSENEILKKELEAMRT-FCESAKQ--DRL-KLQN 465
Query: 214 ETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXS 273
E K L+ + + E KQ+
Sbjct: 466 ELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKE 525
Query: 274 IMKDRLSRAEHQLKTNV-ERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQEL 332
+ + H+L + +++ L+ E A +E L + E+F ++
Sbjct: 526 HLTSEAASGNHRLTEELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIV----EEFKRDE 581
Query: 333 NKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSI-----KDMK----H 383
KL + K L + REK SA SI ++MK +
Sbjct: 582 GKLIEENKRLQKELSMCEMEREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSN 641
Query: 384 EMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLES-ELRVKDLVRELDEKESILE 442
E+N KL+E+E+++ S+ E + L+ +++++ L + + + V+ E++S
Sbjct: 642 EVNEKAKKLVEMEREHEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGEL 701
Query: 443 TKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEID-ELKSKLSTEKAIKDIXXXXXX 501
K+ + L++ E K ++ +LL E+ + E+K+ K +D+
Sbjct: 702 GKKITELTLKNQTLQKEIEKVYLDN--KLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDA 759
Query: 502 XXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLND-----VGNM 556
++ +M+ E +L +++L ++ + +
Sbjct: 760 IIDDLNRKLLDVTQKYTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSN 819
Query: 557 INQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM-LNE 611
I + + +L EL K+ E EK+ +E L + M+ Q +V K +E+KM LN+
Sbjct: 820 IVELKKQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQ-YVPVKTHEEVKMTLND 874
Score = 40.3 bits (90), Expect = 0.023
Identities = 49/242 (20%), Positives = 104/242 (42%), Gaps = 13/242 (5%)
Query: 380 DMKHEMNLNIA-KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKE 438
+ HEM ++ K E+ K+ D + +K T +N+ + + + V+ L +K+
Sbjct: 1052 EKSHEMERALSRKTDELNKQLKD-LSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQ 1110
Query: 439 SI-LETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXX 497
+ LE + ++K L T +E+ K E++ +R ++ + + +L L +K
Sbjct: 1111 HVPLEQVEALKKSLNGT---IENLKEELKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLA 1167
Query: 498 XXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMI 557
+E + ++ EE+ L++++ ++ +V ++
Sbjct: 1168 EHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLETREVVDLS 1227
Query: 558 NQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHM 617
+ K +L + +EKL + R E + E+ VL+ K+KEI +EKE H
Sbjct: 1228 KYKATKS-DLETQISSLNEKLAN----LNRKYEEVCEE--VLHAKKKEISAKDEKELLHF 1280
Query: 618 NI 619
+I
Sbjct: 1281 SI 1282
Score = 39.9 bits (89), Expect = 0.030
Identities = 112/619 (18%), Positives = 254/619 (41%), Gaps = 78/619 (12%)
Query: 23 EQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQK 82
E E + E+ ++K + + V EK +KE+ ++ ++EL L +K +K
Sbjct: 781 EMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEK 840
Query: 83 VNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTL--DNKVTFDVNKLLNIPNSLV 140
++ ++E N+ K+ Q + + E K + TL N+ DV K N
Sbjct: 841 IHALTSENT---NLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEF 897
Query: 141 DKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKE 200
K ++ + EI+ +L + + I + +++ AE++ SSL Q +
Sbjct: 898 VKIKD----KNEILK--RNLENTQNQIKAEYISL------AEHEAKMSSLSQSMRKVQDS 945
Query: 201 INDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXX 260
+I+ RK E + L E+ +L+T ++ + + P +
Sbjct: 946 NAEILANYRKGQEEIVTLHA---EIKAQKKELDTIQECIKVK------YAPIVSFEECER 996
Query: 261 XXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXX 320
+KD+LS + + E V + + ++ + E ++L++ +
Sbjct: 997 KFKATEKE------LKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVL 1050
Query: 321 XXXXXE---DFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKS 377
E ++ ++L + +KD + ++ +EKL S +
Sbjct: 1051 IEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAK--------QTSEILA 1102
Query: 378 IKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEK 437
++++ + ++ + ++ ++K N +IE L+E + ++ + + V L + L+ +
Sbjct: 1103 VQNLLQKQHVPLEQVEALKKSLNGTIEN---LKEELKSMQRCYEKEQQTVTKLHQLLENQ 1159
Query: 438 ESI-------LETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKL-STE 489
++ L+ K+ +KE+ K L ++ E + K EE+ +L+S++ +T+
Sbjct: 1160 KNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQN-------KMEEVSKLQSEVQNTK 1212
Query: 490 KAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDN 549
+A+K + E+Q+ S E+L NL + ++ E +
Sbjct: 1213 QALKKLETREVVDLSKYKATKSDL-------ETQISSLNEKLANLNRKYEEVCE----EV 1261
Query: 550 LNDVGNMINQQRDK-LFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM 608
L+ I+ + +K L + QE D+K + ++ + ++TE + + + K+I+
Sbjct: 1262 LHAKKKEISAKDEKELLHFSIEQEIKDQKERCDKS-----LTTITELQRRIQESAKQIEA 1316
Query: 609 LNEKEEEHMNIINLLHNKL 627
+ K E +N + L L
Sbjct: 1317 KDNKITELLNDVERLKQAL 1335
Score = 38.7 bits (86), Expect = 0.070
Identities = 45/243 (18%), Positives = 106/243 (43%), Gaps = 15/243 (6%)
Query: 380 DMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKES 439
++ H++ A +E E+ DS E+ K L++ + D++ + ESE +VK + +
Sbjct: 466 ELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQM------QTH 519
Query: 440 ILETKQCVQKELESTKTDL-EHRKTEIEEYKRLLFEKGEEIDELKSKL-STEKAIKDIXX 497
L K+ + E S L E K ++++ K E+ +L++++ E +++
Sbjct: 520 FLALKEHLTSEAASGNHRLTEELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKR 579
Query: 498 XXXXXXXXXXXXXXXXXXXXXXRESQMKSYYE---ELMNLKNQITQLREFGAFDNL-NDV 553
RE + + E + L ++ F+N+ + +
Sbjct: 580 DEGKLIEENKRLQKELSMCEMEREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSL 639
Query: 554 GNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK-MLNEK 612
N +N++ KL E+ + E+ +++ + E++ + + +HV ++ +++K L +K
Sbjct: 640 SNEVNEKAKKLVEMEREHEKSLSEIRQLKRELENVKAKLA--QHVKPEEHEQVKSRLEQK 697
Query: 613 EEE 615
E
Sbjct: 698 SGE 700
Score = 37.9 bits (84), Expect = 0.12
Identities = 85/463 (18%), Positives = 171/463 (36%), Gaps = 30/463 (6%)
Query: 171 TLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALS 230
TL + + N E +K + + EF+K I D + L++N T Q++ + +S A
Sbjct: 871 TLNDTLAKTNRELLDVKKKFEDINQEFVK-IKDKNEILKRNLENTQN-QIKAEYISLAEH 928
Query: 231 DLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNV 290
+ + + + AN K L + +K
Sbjct: 929 EAKMSSLSQSMRKVQDSNAEILANYRKGQEEIVTLHAEIKA---QKKELDTIQECIKVKY 985
Query: 291 ERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFD---QELNKLTQSIKDNTTHLE 347
+V E + ++ L+ + E+ QE +KL + I L
Sbjct: 986 APIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLR 1045
Query: 348 DIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKK 407
D + EK NK +KD+ K E++ +EE
Sbjct: 1046 DKTVLIEKSHEMERALSRKTD----ELNKQLKDLSQ-------KYTEVKNVKEKLVEENA 1094
Query: 408 TLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEE 467
I ++ +LL+ + + V L K+S+ T + +++EL+S + E + + +
Sbjct: 1095 KQTSEILAVQ-NLLQKQHVPLEQVEAL--KKSLNGTIENLKEELKSMQRCYEKEQQTVTK 1151
Query: 468 YKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSY 527
+LL + L L ++A + +S++++
Sbjct: 1152 LHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNT 1211
Query: 528 YEELMNLKN-QITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEY-DEKLQTKENEI 585
+ L L+ ++ L ++ A +D+ I+ +KL L ++ EE +E L K+ EI
Sbjct: 1212 KQALKKLETREVVDLSKYKA--TKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEI 1269
Query: 586 KRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
+ E+E + E+EIK E+ ++ + I L +++
Sbjct: 1270 S----AKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQ 1308
>BC103765-1|AAI03766.1| 691|Homo sapiens NUMA1 protein protein.
Length = 691
Score = 45.2 bits (102), Expect = 8e-04
Identities = 73/379 (19%), Positives = 150/379 (39%), Gaps = 29/379 (7%)
Query: 277 DRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLT 336
DRL+ + + +LE ++ S + L T+ + D+++N+L+
Sbjct: 259 DRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQDLKTEKSQ-MDRKINQLS 317
Query: 337 QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIE 396
+ D + L + A ++LQ + + + ++ E++ + +E
Sbjct: 318 EENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLE 377
Query: 397 KKYNDSIEEKKT-LQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTK 455
+K N+ ++ K + L+E++ L+ + + + V V +L+ + T +L++
Sbjct: 378 EK-NEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARV 436
Query: 456 TDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXX 515
LE + + E +LL E+G +E K +LS+ I D+
Sbjct: 437 EMLETERGQQEA--KLLAERGH-FEEEKQQLSS--LITDLQSSISNLSQAKEELEQASQA 491
Query: 516 XXXXRESQMKSYYEELMNLKNQITQL-REFG-----AFDNLNDVGNMINQQRDKLFELTK 569
+Q+ S EL L I Q +E A + + + QQ L
Sbjct: 492 HGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRH 551
Query: 570 RQEEYDEKLQTKENEIKRLVESM--TEQEHV-------------LNKKEKEIKMLNEKEE 614
+ E+ L+ KE ++K + E T Q+H L +++ +K L E+
Sbjct: 552 QVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEK 611
Query: 615 EHMNIINLLHNKLELRNEA 633
E + +L +L++ NEA
Sbjct: 612 EKAAKLEILQQQLQVANEA 630
Score = 33.1 bits (72), Expect = 3.5
Identities = 67/371 (18%), Positives = 138/371 (37%), Gaps = 40/371 (10%)
Query: 117 EHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKI 176
E+ L K+ + L + ++L + EE K W E EK +S K
Sbjct: 319 ENGDLSFKLREFASHLQQLQDALNELTEE---HSKATQEWLEKQAQLEKELSAALQDKKC 375
Query: 177 KEFNAENDLLKSSLDQLRTEFLKEIND---------IIDCLRKNA--NETMALQLRTKEL 225
E +N++L+ L QL E L ++ D + D L+ E L +L
Sbjct: 376 LE--EKNEILQGKLSQLE-EHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQL 432
Query: 226 SCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEH- 284
+ L T+ + ++ + H + S K+ L +A
Sbjct: 433 QARVEMLETERGQQEAKLLAERGHFE-EEKQQLSSLITDLQSSISNLSQAKEELEQASQA 491
Query: 285 -------QLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQ------- 330
Q+ + + L A ++Q E L++ + +Q
Sbjct: 492 HGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRH 551
Query: 331 ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIA 390
++ +L+ S+K L+++A EK ++ + S+++ + L
Sbjct: 552 QVEQLSSSLKQKEQQLKEVA---EKQEATRQDHAQQLATAAEEREASLRE--RDAALKQL 606
Query: 391 KLIEIEKKYNDSI--EEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQ 448
+ +E EK I ++ + E D +T + +++ +L R+++E ++ +ET + Q
Sbjct: 607 EALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQ 666
Query: 449 KELESTKTDLE 459
E ++ +LE
Sbjct: 667 HEAQAQVAELE 677
>BC027493-1|AAH27493.1| 691|Homo sapiens Unknown (protein for
IMAGE:4540541) protein.
Length = 691
Score = 45.2 bits (102), Expect = 8e-04
Identities = 73/379 (19%), Positives = 150/379 (39%), Gaps = 29/379 (7%)
Query: 277 DRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLT 336
DRL+ + + +LE ++ S + L T+ + D+++N+L+
Sbjct: 259 DRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQDLKTEKSQ-MDRKINQLS 317
Query: 337 QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIE 396
+ D + L + A ++LQ + + + ++ E++ + +E
Sbjct: 318 EENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLE 377
Query: 397 KKYNDSIEEKKT-LQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTK 455
+K N+ ++ K + L+E++ L+ + + + V V +L+ + T +L++
Sbjct: 378 EK-NEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARV 436
Query: 456 TDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXX 515
LE + + E +LL E+G +E K +LS+ I D+
Sbjct: 437 EMLETERGQQEA--KLLAERGH-FEEEKQQLSS--LITDLQSSISNLSQAKEELEQASQA 491
Query: 516 XXXXRESQMKSYYEELMNLKNQITQL-REFG-----AFDNLNDVGNMINQQRDKLFELTK 569
+Q+ S EL L I Q +E A + + + QQ L
Sbjct: 492 HGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRH 551
Query: 570 RQEEYDEKLQTKENEIKRLVESM--TEQEHV-------------LNKKEKEIKMLNEKEE 614
+ E+ L+ KE ++K + E T Q+H L +++ +K L E+
Sbjct: 552 QVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEK 611
Query: 615 EHMNIINLLHNKLELRNEA 633
E + +L +L++ NEA
Sbjct: 612 EKAAKLEILQQQLQVANEA 630
Score = 33.1 bits (72), Expect = 3.5
Identities = 67/371 (18%), Positives = 138/371 (37%), Gaps = 40/371 (10%)
Query: 117 EHSTLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKI 176
E+ L K+ + L + ++L + EE K W E EK +S K
Sbjct: 319 ENGDLSFKLREFASHLQQLQDALNELTEE---HSKATQEWLEKQAQLEKELSAALQDKKC 375
Query: 177 KEFNAENDLLKSSLDQLRTEFLKEIND---------IIDCLRKNA--NETMALQLRTKEL 225
E +N++L+ L QL E L ++ D + D L+ E L +L
Sbjct: 376 LE--EKNEILQGKLSQLE-EHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQL 432
Query: 226 SCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEH- 284
+ L T+ + ++ + H + S K+ L +A
Sbjct: 433 QARVEMLETERGQQEAKLLAERGHFE-EEKQQLSSLITDLQSSISNLSQAKEELEQASQA 491
Query: 285 -------QLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQ------- 330
Q+ + + L A ++Q E L++ + +Q
Sbjct: 492 HGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRH 551
Query: 331 ELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIA 390
++ +L+ S+K L+++A EK ++ + S+++ + L
Sbjct: 552 QVEQLSSSLKQKEQQLKEVA---EKQEATRQDHAQQLATAAEEREASLRE--RDAALKQL 606
Query: 391 KLIEIEKKYNDSI--EEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQ 448
+ +E EK I ++ + E D +T + +++ +L R+++E ++ +ET + Q
Sbjct: 607 EALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQ 666
Query: 449 KELESTKTDLE 459
E ++ +LE
Sbjct: 667 HEAQAQVAELE 677
>AF322916-1|AAG49577.1| 1416|Homo sapiens uveal autoantigen protein.
Length = 1416
Score = 45.2 bits (102), Expect = 8e-04
Identities = 112/596 (18%), Positives = 230/596 (38%), Gaps = 44/596 (7%)
Query: 49 EKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVN---LPSAEELHIMNVAKLSPEQLL 105
++ + ++D + + +L LR ++ ++L KVN L EE+ + + + E+L
Sbjct: 290 QREHQNIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESEREKLK 349
Query: 106 QLCAGGEPKALEH----STLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIIN------ 155
L A E + E L N+ + + L + ++ E+ L K+ ++
Sbjct: 350 SLLAAKEKQHEESLRTIEALKNRFKYFESDHLGSGSHFSNRKEDMLLKQGQMYMADSQCT 409
Query: 156 --WFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNAN 213
+ M + L++ + +EN++LK L+ +RT F + D L K N
Sbjct: 410 SPGIPAHMQSRSMLRPLELSLPSQTSYSENEILKKELEAMRT-FCESAKQ--DRL-KLQN 465
Query: 214 ETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXS 273
E K L+ + + E KQ+
Sbjct: 466 ELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKE 525
Query: 274 IMKDRLSRAEHQLKTNV-ERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQEL 332
+ + H+L + +++ L+ E A +E L + E+F ++
Sbjct: 526 HLTSEAASGNHRLTEELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIV----EEFKRDE 581
Query: 333 NKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSI-----KDMK----H 383
KL + K L + REK SA SI ++MK +
Sbjct: 582 GKLIEENKRLQKELSMCEMEREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSN 641
Query: 384 EMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLES-ELRVKDLVRELDEKESILE 442
E+N KL+E+E+++ S+ E + L+ +++++ L + + + V+ E++S
Sbjct: 642 EVNEKAKKLVEMEREHEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGEL 701
Query: 443 TKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEID-ELKSKLSTEKAIKDIXXXXXX 501
K+ + L++ E K ++ +LL E+ + E+K+ K +D+
Sbjct: 702 GKKITELTLKNQTLQKEIEKVYLDN--KLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDA 759
Query: 502 XXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLND-----VGNM 556
++ +M+ E +L +++L ++ + +
Sbjct: 760 IIDDLNRKLLDVTQKYTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSN 819
Query: 557 INQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM-LNE 611
I + + +L EL K+ E EK+ +E L + M+ Q +V K +E+KM LN+
Sbjct: 820 IVELKKQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQ-YVPVKTHEEVKMTLND 874
Score = 40.3 bits (90), Expect = 0.023
Identities = 49/242 (20%), Positives = 104/242 (42%), Gaps = 13/242 (5%)
Query: 380 DMKHEMNLNIA-KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKE 438
+ HEM ++ K E+ K+ D + +K T +N+ + + + V+ L +K+
Sbjct: 1052 EKSHEMERALSRKTDELNKQLKD-LSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQ 1110
Query: 439 SI-LETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXX 497
+ LE + ++K L T +E+ K E++ +R ++ + + +L L +K
Sbjct: 1111 HVPLEQVEALKKSLNGT---IENLKEELKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLA 1167
Query: 498 XXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMI 557
+E + ++ EE+ L++++ ++ +V ++
Sbjct: 1168 EHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLETREVVDLS 1227
Query: 558 NQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHM 617
+ K +L + +EKL + R E + E+ VL+ K+KEI +EKE H
Sbjct: 1228 KYKATKS-DLETQISSLNEKLAN----LNRKYEEVCEE--VLHAKKKEISAKDEKELLHF 1280
Query: 618 NI 619
+I
Sbjct: 1281 SI 1282
Score = 39.9 bits (89), Expect = 0.030
Identities = 112/619 (18%), Positives = 254/619 (41%), Gaps = 78/619 (12%)
Query: 23 EQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQK 82
E E + E+ ++K + + V EK +KE+ ++ ++EL L +K +K
Sbjct: 781 EMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEK 840
Query: 83 VNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTL--DNKVTFDVNKLLNIPNSLV 140
++ ++E N+ K+ Q + + E K + TL N+ DV K N
Sbjct: 841 IHALTSENT---NLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEF 897
Query: 141 DKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKE 200
K ++ + EI+ +L + + I + +++ AE++ SSL Q +
Sbjct: 898 VKIKD----KNEILK--RNLENTQNQIKAEYISL------AEHEAKMSSLSQSMRKVQDS 945
Query: 201 INDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXX 260
+I+ RK E + L E+ +L+T ++ + + P +
Sbjct: 946 NAEILANYRKGQEEIVTLHA---EIKAQKKELDTIQECIKVK------YAPIVSFEECER 996
Query: 261 XXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXX 320
+KD+LS + + E V + + ++ + E ++L++ +
Sbjct: 997 KFKATEKE------LKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVL 1050
Query: 321 XXXXXE---DFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKS 377
E ++ ++L + +KD + ++ +EKL S +
Sbjct: 1051 IEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAK--------QTSEILA 1102
Query: 378 IKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEK 437
++++ + ++ + ++ ++K N +IE L+E + ++ + + V L + L+ +
Sbjct: 1103 VQNLLQKQHVPLEQVEALKKSLNGTIEN---LKEELKSMQRCYEKEQQTVTKLHQLLENQ 1159
Query: 438 ESI-------LETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKL-STE 489
++ L+ K+ +KE+ K L ++ E + K EE+ +L+S++ +T+
Sbjct: 1160 KNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQN-------KMEEVSKLQSEVQNTK 1212
Query: 490 KAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDN 549
+A+K + E+Q+ S E+L NL + ++ E +
Sbjct: 1213 QALKKLETREVVDLSKYKATKSDL-------ETQISSLNEKLANLNRKYEEVCE----EV 1261
Query: 550 LNDVGNMINQQRDK-LFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM 608
L+ I+ + +K L + QE D+K + ++ + ++TE + + + K+I+
Sbjct: 1262 LHAKKKEISAKDEKELLHFSIEQEIKDQKERCDKS-----LTTITELQRRIQESAKQIEA 1316
Query: 609 LNEKEEEHMNIINLLHNKL 627
+ K E +N + L L
Sbjct: 1317 KDNKITELLNDVERLKQAL 1335
Score = 38.7 bits (86), Expect = 0.070
Identities = 45/243 (18%), Positives = 106/243 (43%), Gaps = 15/243 (6%)
Query: 380 DMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKES 439
++ H++ A +E E+ DS E+ K L++ + D++ + ESE +VK + +
Sbjct: 466 ELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQM------QTH 519
Query: 440 ILETKQCVQKELESTKTDL-EHRKTEIEEYKRLLFEKGEEIDELKSKL-STEKAIKDIXX 497
L K+ + E S L E K ++++ K E+ +L++++ E +++
Sbjct: 520 FLALKEHLTSEAASGNHRLTEELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKR 579
Query: 498 XXXXXXXXXXXXXXXXXXXXXXRESQMKSYYE---ELMNLKNQITQLREFGAFDNL-NDV 553
RE + + E + L ++ F+N+ + +
Sbjct: 580 DEGKLIEENKRLQKELSMCEMEREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSL 639
Query: 554 GNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK-MLNEK 612
N +N++ KL E+ + E+ +++ + E++ + + +HV ++ +++K L +K
Sbjct: 640 SNEVNEKAKKLVEMEREHEKSLSEIRQLKRELENVKAKLA--QHVKPEEHEQVKSRLEQK 697
Query: 613 EEE 615
E
Sbjct: 698 SGE 700
Score = 37.9 bits (84), Expect = 0.12
Identities = 85/463 (18%), Positives = 171/463 (36%), Gaps = 30/463 (6%)
Query: 171 TLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALS 230
TL + + N E +K + + EF+K I D + L++N T Q++ + +S A
Sbjct: 871 TLNDTLAKTNRELLDVKKKFEDINQEFVK-IKDKNEILKRNLENTQN-QIKAEYISLAEH 928
Query: 231 DLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNV 290
+ + + + AN K L + +K
Sbjct: 929 EAKMSSLSQSMRKVQDSNAEILANYRKGQEEIVTLHAEIKA---QKKELDTIQECIKVKY 985
Query: 291 ERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFD---QELNKLTQSIKDNTTHLE 347
+V E + ++ L+ + E+ QE +KL + I L
Sbjct: 986 APIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLR 1045
Query: 348 DIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKK 407
D + EK NK +KD+ K E++ +EE
Sbjct: 1046 DKTVLIEKSHEMERALSRKTD----ELNKQLKDLSQ-------KYTEVKNVKEKLVEENA 1094
Query: 408 TLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEE 467
I ++ +LL+ + + V L K+S+ T + +++EL+S + E + + +
Sbjct: 1095 KQTSEILAVQ-NLLQKQHVPLEQVEAL--KKSLNGTIENLKEELKSMQRCYEKEQQTVTK 1151
Query: 468 YKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSY 527
+LL + L L ++A + +S++++
Sbjct: 1152 LHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNT 1211
Query: 528 YEELMNLKN-QITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEY-DEKLQTKENEI 585
+ L L+ ++ L ++ A +D+ I+ +KL L ++ EE +E L K+ EI
Sbjct: 1212 KQALKKLETREVVDLSKYKA--TKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEI 1269
Query: 586 KRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
+ E+E + E+EIK E+ ++ + I L +++
Sbjct: 1270 S----AKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQ 1308
>AB210007-1|BAE06089.1| 2121|Homo sapiens NUMA1 variant protein
protein.
Length = 2121
Score = 45.2 bits (102), Expect = 8e-04
Identities = 73/379 (19%), Positives = 150/379 (39%), Gaps = 29/379 (7%)
Query: 277 DRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLT 336
DRL+ + + +LE ++ S + L T+ + D+++N+L+
Sbjct: 265 DRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQDLKTEKSQ-MDRKINQLS 323
Query: 337 QSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIE 396
+ D + L + A ++LQ + + + ++ E++ + +E
Sbjct: 324 EENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLE 383
Query: 397 KKYNDSIEEKKT-LQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTK 455
+K N+ ++ K + L+E++ L+ + + + V V +L+ + T +L++
Sbjct: 384 EK-NEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARV 442
Query: 456 TDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXX 515
LE + + E +LL E+G +E K +LS+ I D+
Sbjct: 443 EMLETERGQQEA--KLLAERGH-FEEEKQQLSS--LITDLQSSISNLSQAKEELEQASQA 497
Query: 516 XXXXRESQMKSYYEELMNLKNQITQL-REFG-----AFDNLNDVGNMINQQRDKLFELTK 569
+Q+ S EL L I Q +E A + + + QQ L
Sbjct: 498 HGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRH 557
Query: 570 RQEEYDEKLQTKENEIKRLVESM--TEQEHV-------------LNKKEKEIKMLNEKEE 614
+ E+ L+ KE ++K + E T Q+H L +++ +K L E+
Sbjct: 558 QVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEK 617
Query: 615 EHMNIINLLHNKLELRNEA 633
E + +L +L++ NEA
Sbjct: 618 EKAAKLEILQQQLQVANEA 636
Score = 41.9 bits (94), Expect = 0.007
Identities = 65/357 (18%), Positives = 137/357 (38%), Gaps = 15/357 (4%)
Query: 147 LFKRKEIINWFESLMSQEKG------ISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKE 200
L + +E ++ + QEKG + +TL + A N L++ ++ L TE ++
Sbjct: 393 LSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQ 452
Query: 201 INDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRK--QIHSGDHHRPYAN-RNX 257
++ E L +L ++S+L+ E+ + Q H A+ +
Sbjct: 453 EAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSE 512
Query: 258 XXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAAL----EQARSESWSLERT 313
+ +K + + QL +++ Q L EQ S E+
Sbjct: 513 LTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQ 572
Query: 314 VXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAR-EKLQSXXXXXXXXXXXXSA 372
+ +D Q+L + ++ + D AL + E L+
Sbjct: 573 LKEVAEKQEATRQDHAQQLATAAEE-REASLRERDAALKQLEALEKEKAAKLEILQQQLQ 631
Query: 373 SYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVR 432
N++ + + + E+ +K + +T ++ + + + E EL+++ +
Sbjct: 632 VANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQ 691
Query: 433 ELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
+ EKE + + K +Q++L++ K L+ K +EE KR + EE S+L E
Sbjct: 692 KATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAE 748
Score = 37.1 bits (82), Expect = 0.21
Identities = 44/216 (20%), Positives = 90/216 (41%), Gaps = 9/216 (4%)
Query: 281 RAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQSIK 340
RA+ L +LE L+ A +E T+ E DQEL KL
Sbjct: 1021 RAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEA 1080
Query: 341 DNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKS---IKDMKHEMNLNIAKLIEIEK 397
LE++ ++L+ S + +++ + ++ A++ ++E+
Sbjct: 1081 AQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQ 1140
Query: 398 KYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQ----CVQKELES 453
+ E+ +L+ +++ R E + ++ L +L+EK L Q Q+EL +
Sbjct: 1141 QCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAA 1200
Query: 454 TKTDL-EHRKTEIEEYKRLLFEKGEEIDELKSKLST 488
+T + +H K E +E+K + +E + S +S+
Sbjct: 1201 FRTKVQDHSKAE-DEWKAQVARGRQEAERKNSLISS 1235
Score = 35.9 bits (79), Expect = 0.49
Identities = 23/113 (20%), Positives = 54/113 (47%), Gaps = 2/113 (1%)
Query: 375 NKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVREL 434
+K + D + KL ++ + +S +E + LQ +++L+ L + E + ++
Sbjct: 1561 SKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQM 1620
Query: 435 DEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDE--LKSK 485
++ ++ + K+ +EL+ LE + E +E + G E+ + LK+K
Sbjct: 1621 EKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTK 1673
Score = 33.1 bits (72), Expect = 3.5
Identities = 46/245 (18%), Positives = 99/245 (40%), Gaps = 11/245 (4%)
Query: 372 ASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRV--KD 429
A ++ + ++ E +L ++K + EE + L E + L LE EL +
Sbjct: 1423 AEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERAN-LGRQFLEVELDQAREK 1481
Query: 430 LVRELDEKESILETKQC-VQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLST 488
V+EL + ET+ VQ+E +ST +LE + E K + E+ + E + KL+
Sbjct: 1482 YVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLTA 1541
Query: 489 E-KAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAF 547
+ + ++ ++ ++K+ + + + +L+
Sbjct: 1542 QVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQA---- 1597
Query: 548 DNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK 607
LN++ ++Q+ + E+ K+ + + L E + E L K+ KE++
Sbjct: 1598 -QLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQ-LQKENKELR 1655
Query: 608 MLNEK 612
E+
Sbjct: 1656 AEAER 1660
>AB046781-1|BAB13387.2| 1416|Homo sapiens KIAA1561 protein protein.
Length = 1416
Score = 45.2 bits (102), Expect = 8e-04
Identities = 112/596 (18%), Positives = 230/596 (38%), Gaps = 44/596 (7%)
Query: 49 EKSKKELEDRQNQVMELYASLRNTHRKMKLLGQKVN---LPSAEELHIMNVAKLSPEQLL 105
++ + ++D + + +L LR ++ ++L KVN L EE+ + + + E+L
Sbjct: 290 QREHQNIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESEREKLK 349
Query: 106 QLCAGGEPKALEH----STLDNKVTFDVNKLLNIPNSLVDKCEETLFKRKEIIN------ 155
L A E + E L N+ + + L + ++ E+ L K+ ++
Sbjct: 350 SLLAAKEKQHEESLRTIEALKNRFKYFESDHLGSGSHFSNRKEDMLLKQGQMYMADSQCT 409
Query: 156 --WFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNAN 213
+ M + L++ + +EN++LK L+ +RT F + D L K N
Sbjct: 410 SPGIPAHMQSRSMLRPLELSLPSQTSYSENEILKKELEAMRT-FCESAKQ--DRL-KLQN 465
Query: 214 ETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXS 273
E K L+ + + E KQ+
Sbjct: 466 ELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKE 525
Query: 274 IMKDRLSRAEHQLKTNV-ERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQEL 332
+ + H+L + +++ L+ E A +E L + E+F ++
Sbjct: 526 HLTSEAASGNHRLTEELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIV----EEFKRDE 581
Query: 333 NKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSI-----KDMK----H 383
KL + K L + REK SA SI ++MK +
Sbjct: 582 GKLIEENKRLQKELSMCEMEREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSN 641
Query: 384 EMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLES-ELRVKDLVRELDEKESILE 442
E+N KL+E+E+++ S+ E + L+ +++++ L + + + V+ E++S
Sbjct: 642 EVNEKAKKLVEMEREHEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGEL 701
Query: 443 TKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEID-ELKSKLSTEKAIKDIXXXXXX 501
K+ + L++ E K ++ +LL E+ + E+K+ K +D+
Sbjct: 702 GKKITELTLKNQTLQKEIEKVYLDN--KLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDA 759
Query: 502 XXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLND-----VGNM 556
++ +M+ E +L +++L ++ + +
Sbjct: 760 IIDDLNRKLLDVTQKYTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSN 819
Query: 557 INQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM-LNE 611
I + + +L EL K+ E EK+ +E L + M+ Q +V K +E+KM LN+
Sbjct: 820 IVELKKQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQ-YVPVKTHEEVKMTLND 874
Score = 40.3 bits (90), Expect = 0.023
Identities = 49/242 (20%), Positives = 104/242 (42%), Gaps = 13/242 (5%)
Query: 380 DMKHEMNLNIA-KLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKE 438
+ HEM ++ K E+ K+ D + +K T +N+ + + + V+ L +K+
Sbjct: 1052 EKSHEMERALSRKTDELNKQLKD-LSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQ 1110
Query: 439 SI-LETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXX 497
+ LE + ++K L T +E+ K E++ +R ++ + + +L L +K
Sbjct: 1111 HVPLEQVEALKKSLNGT---IENLKEELKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLA 1167
Query: 498 XXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMI 557
+E + ++ EE+ L++++ ++ +V ++
Sbjct: 1168 EHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLETREVVDLS 1227
Query: 558 NQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHM 617
+ K +L + +EKL + R E + E+ VL+ K+KEI +EKE H
Sbjct: 1228 KYKATKS-DLETQISSLNEKLAN----LNRKYEEVCEE--VLHAKKKEISAKDEKELLHF 1280
Query: 618 NI 619
+I
Sbjct: 1281 SI 1282
Score = 39.9 bits (89), Expect = 0.030
Identities = 112/619 (18%), Positives = 254/619 (41%), Gaps = 78/619 (12%)
Query: 23 EQESITSESHKITKLKTVWQEKMVTFEKSKKELEDRQNQVMELYASLRNTHRKMKLLGQK 82
E E + E+ ++K + + V EK +KE+ ++ ++EL L +K +K
Sbjct: 781 EMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEK 840
Query: 83 VNLPSAEELHIMNVAKLSPEQLLQLCAGGEPKALEHSTL--DNKVTFDVNKLLNIPNSLV 140
++ ++E N+ K+ Q + + E K + TL N+ DV K N
Sbjct: 841 IHALTSENT---NLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEF 897
Query: 141 DKCEETLFKRKEIINWFESLMSQEKGISTKTLTMKIKEFNAENDLLKSSLDQLRTEFLKE 200
K ++ + EI+ +L + + I + +++ AE++ SSL Q +
Sbjct: 898 VKIKD----KNEILK--RNLENTQNQIKAEYISL------AEHEAKMSSLSQSMRKVQDS 945
Query: 201 INDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXX 260
+I+ RK E + L E+ +L+T ++ + + P +
Sbjct: 946 NAEILANYRKGQEEIVTLHA---EIKAQKKELDTIQECIKVK------YAPIVSFEECER 996
Query: 261 XXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXX 320
+KD+LS + + E V + + ++ + E ++L++ +
Sbjct: 997 KFKATEKE------LKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVL 1050
Query: 321 XXXXXE---DFDQELNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKS 377
E ++ ++L + +KD + ++ +EKL S +
Sbjct: 1051 IEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAK--------QTSEILA 1102
Query: 378 IKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEK 437
++++ + ++ + ++ ++K N +IE L+E + ++ + + V L + L+ +
Sbjct: 1103 VQNLLQKQHVPLEQVEALKKSLNGTIEN---LKEELKSMQRCYEKEQQTVTKLHQLLENQ 1159
Query: 438 ESI-------LETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKL-STE 489
++ L+ K+ +KE+ K L ++ E + K EE+ +L+S++ +T+
Sbjct: 1160 KNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQN-------KMEEVSKLQSEVQNTK 1212
Query: 490 KAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDN 549
+A+K + E+Q+ S E+L NL + ++ E +
Sbjct: 1213 QALKKLETREVVDLSKYKATKSDL-------ETQISSLNEKLANLNRKYEEVCE----EV 1261
Query: 550 LNDVGNMINQQRDK-LFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM 608
L+ I+ + +K L + QE D+K + ++ + ++TE + + + K+I+
Sbjct: 1262 LHAKKKEISAKDEKELLHFSIEQEIKDQKERCDKS-----LTTITELQRRIQESAKQIEA 1316
Query: 609 LNEKEEEHMNIINLLHNKL 627
+ K E +N + L L
Sbjct: 1317 KDNKITELLNDVERLKQAL 1335
Score = 38.7 bits (86), Expect = 0.070
Identities = 45/243 (18%), Positives = 106/243 (43%), Gaps = 15/243 (6%)
Query: 380 DMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKES 439
++ H++ A +E E+ DS E+ K L++ + D++ + ESE +VK + +
Sbjct: 466 ELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQM------QTH 519
Query: 440 ILETKQCVQKELESTKTDL-EHRKTEIEEYKRLLFEKGEEIDELKSKL-STEKAIKDIXX 497
L K+ + E S L E K ++++ K E+ +L++++ E +++
Sbjct: 520 FLALKEHLTSEAASGNHRLTEELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKR 579
Query: 498 XXXXXXXXXXXXXXXXXXXXXXRESQMKSYYE---ELMNLKNQITQLREFGAFDNL-NDV 553
RE + + E + L ++ F+N+ + +
Sbjct: 580 DEGKLIEENKRLQKELSMCEMEREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSL 639
Query: 554 GNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK-MLNEK 612
N +N++ KL E+ + E+ +++ + E++ + + +HV ++ +++K L +K
Sbjct: 640 SNEVNEKAKKLVEMEREHEKSLSEIRQLKRELENVKAKLA--QHVKPEEHEQVKSRLEQK 697
Query: 613 EEE 615
E
Sbjct: 698 SGE 700
Score = 37.9 bits (84), Expect = 0.12
Identities = 85/463 (18%), Positives = 171/463 (36%), Gaps = 30/463 (6%)
Query: 171 TLTMKIKEFNAENDLLKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALS 230
TL + + N E +K + + EF+K I D + L++N T Q++ + +S A
Sbjct: 871 TLNDTLAKTNRELLDVKKKFEDINQEFVK-IKDKNEILKRNLENTQN-QIKAEYISLAEH 928
Query: 231 DLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNV 290
+ + + + AN K L + +K
Sbjct: 929 EAKMSSLSQSMRKVQDSNAEILANYRKGQEEIVTLHAEIKA---QKKELDTIQECIKVKY 985
Query: 291 ERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFD---QELNKLTQSIKDNTTHLE 347
+V E + ++ L+ + E+ QE +KL + I L
Sbjct: 986 APIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLR 1045
Query: 348 DIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKK 407
D + EK NK +KD+ K E++ +EE
Sbjct: 1046 DKTVLIEKSHEMERALSRKTD----ELNKQLKDLSQ-------KYTEVKNVKEKLVEENA 1094
Query: 408 TLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEE 467
I ++ +LL+ + + V L K+S+ T + +++EL+S + E + + +
Sbjct: 1095 KQTSEILAVQ-NLLQKQHVPLEQVEAL--KKSLNGTIENLKEELKSMQRCYEKEQQTVTK 1151
Query: 468 YKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSY 527
+LL + L L ++A + +S++++
Sbjct: 1152 LHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNT 1211
Query: 528 YEELMNLKN-QITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEY-DEKLQTKENEI 585
+ L L+ ++ L ++ A +D+ I+ +KL L ++ EE +E L K+ EI
Sbjct: 1212 KQALKKLETREVVDLSKYKA--TKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEI 1269
Query: 586 KRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
+ E+E + E+EIK E+ ++ + I L +++
Sbjct: 1270 S----AKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQ 1308
>BC117132-1|AAI17133.1| 1306|Homo sapiens kinectin 1 (kinesin
receptor) protein.
Length = 1306
Score = 44.8 bits (101), Expect = 0.001
Identities = 76/353 (21%), Positives = 147/353 (41%), Gaps = 30/353 (8%)
Query: 276 KDR-LSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNK 334
KD+ + + E L + +R+ E L+ ++ ++ L+ V EL K
Sbjct: 612 KDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAA-HELEK 670
Query: 335 LTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIE 394
+ QS+ + I L E+LQ + NK++K ++ ++
Sbjct: 671 MQQSVYVKD---DKIRLLEEQLQHEISNKMEEFKILN-DQNKALKSEVQKLQTLVS---- 722
Query: 395 IEKKYNDSIEE-KKTLQENIDDLRT--DLLESELRVKDLVRELDEKESILETKQCVQKEL 451
E+ D +E+ +K +QE + L+T +LLE+ L ++ +E +E +I + KE+
Sbjct: 723 -EQPNKDVVEQMEKCIQEKDEKLKTVEELLETGL-IQVATKE-EELNAIRTENSSLTKEV 779
Query: 452 ESTKT---DLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXX 508
+ K D + +EE K+++ EK +I ++ L E + +
Sbjct: 780 QDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAE--LLKVANKEKTVQLSITS 837
Query: 509 XXXXXXXXXXXRESQM---KSYYEE----LMNLKNQITQLREFGAFDNLNDVGNMINQQR 561
+E QM K+ EE L N + L+E ++L + Q
Sbjct: 838 KVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEEN--ESLKAHVQEVAQHN 895
Query: 562 DKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEE 614
K + EE + L+ KENE+KRL + E+E L+ K + ++ + ++ +
Sbjct: 896 LKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENK 948
Score = 40.3 bits (90), Expect = 0.023
Identities = 101/521 (19%), Positives = 204/521 (39%), Gaps = 39/521 (7%)
Query: 2 KQEELEIQQNQTDGCLYEDLNEQESITSESHK--ITKLKTVWQEKMVTFEKSKKELEDRQ 59
K EE +I +Q E Q ++ + +K + +++ QEK + ++ LE
Sbjct: 696 KMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGL 755
Query: 60 NQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLC--AGGEPKALE 117
QV L + L ++V A++ ++ A L E+L ++ G+ K++E
Sbjct: 756 IQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLV-EELKKVIHEKDGKIKSVE 814
Query: 118 HSTLDNKVTFDVNKLLNIPNSLVDKCEE--TLFKRKEI-INWFESLMSQEKGISTKTLTM 174
L+ ++ NK + S+ K +E L K KE +N ++++ +EK
Sbjct: 815 E-LLEAELLKVANKEKTVQLSITSKVQELQNLLKGKEEQMNTMKAVL-EEKEKDLANTGK 872
Query: 175 KIKEFNAENDLLKSSLDQLRTEFLKEIN------DIIDCLRKNANETMALQLRTKELSCA 228
+++ EN+ LK+ + ++ LKE + ++ L++ NE L+ KE
Sbjct: 873 WLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESD 932
Query: 229 LS-------DLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMK----- 276
LS D+ +N + QI + I
Sbjct: 933 LSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNEL 992
Query: 277 DRLSRA-EHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKL 335
D L A EHQ K N + + A+E S L+ V E + E ++
Sbjct: 993 DSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEV 1052
Query: 336 TQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEI 395
+ + + +++ E L S S + + K + + L+++
Sbjct: 1053 LKKLFPKVSVPSNLSYG-EWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQL 1111
Query: 396 E-KKYNDSIEE--------KKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQC 446
E +KY + E ++++++ + + + ES +K + E LE +
Sbjct: 1112 ECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRS 1171
Query: 447 VQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS 487
K++E+ + + EH + E+E+ + E+ ELK++L+
Sbjct: 1172 ENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKAQLN 1212
Score = 32.7 bits (71), Expect = 4.6
Identities = 47/237 (19%), Positives = 89/237 (37%), Gaps = 15/237 (6%)
Query: 379 KDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKE 438
+ ++ +M IA L + D++ E+ + L + LV EL EK
Sbjct: 409 QQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYA--RLVNELTEKT 466
Query: 439 SILETKQCVQKELESTKTDL-------EHRKTEIEEYKRLLFEKGEEIDE-LKSKLSTEK 490
L+ ++ +K E T L E R E++ Y R + E + L+SK ++
Sbjct: 467 GKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKE 526
Query: 491 AIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNL 550
++ ES+ K +E +L+ Q+ + E + L
Sbjct: 527 --NEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKE-ESLQMQVQDILEQN--EAL 581
Query: 551 NDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK 607
+ Q + EE + + K+ +IK+ +S+ + L KE+E+K
Sbjct: 582 KAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELK 638
>BC114213-1|AAI14214.1| 1392|Homo sapiens CAP-GLY domain containing
linker protein 1 protein.
Length = 1392
Score = 44.8 bits (101), Expect = 0.001
Identities = 71/361 (19%), Positives = 150/361 (41%), Gaps = 46/361 (12%)
Query: 275 MKDRLSRAEHQLKTNVERVVQ-LEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQ--- 330
+++ LS Q+K +E+ +Q L+ +A E+ S++R++ E F+
Sbjct: 789 LQENLSEVS-QVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSS 847
Query: 331 ELNKLTQSIKDNTTHL-------EDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKH 383
+L KL +++ D E + A+EKL++ S+ K M
Sbjct: 848 DLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTK----MND 903
Query: 384 EMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILET 443
E+ L + E++ K + E LQ++I+D+ +S+ ++ ++ +E++ LE
Sbjct: 904 ELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQ---QEAAKKHEEEKKELER 960
Query: 444 KQC-VQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXX 502
K ++K++E++ + K Y+R E + +E+ L +K + D
Sbjct: 961 KLSDLEKKMETSHNQCQELKAR---YERATSETKTKHEEILQNL--QKTLLD-------- 1007
Query: 503 XXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRD 562
RE +EL L+ Q + + ++ + + +++
Sbjct: 1008 ---------TEDKLKGAREEN-SGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKT 1057
Query: 563 KLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINL 622
+ + ++ + KLQ NE+ L E+ + LNK ++ + + N+K EE I
Sbjct: 1058 ETLASLEDTKQTNAKLQ---NELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIET 1114
Query: 623 L 623
L
Sbjct: 1115 L 1115
Score = 38.7 bits (86), Expect = 0.070
Identities = 26/91 (28%), Positives = 49/91 (53%), Gaps = 4/91 (4%)
Query: 409 LQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLE----HRKTE 464
L+ +D LRT + ++ +L+ +L+E++ +E Q +E TK DLE K+
Sbjct: 406 LEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSR 465
Query: 465 IEEYKRLLFEKGEEIDELKSKLSTEKAIKDI 495
I E ++ L + +E+ EL+ +L + K D+
Sbjct: 466 IMELEKDLALRVQEVAELRRRLESNKPAGDV 496
Score = 37.1 bits (82), Expect = 0.21
Identities = 68/346 (19%), Positives = 130/346 (37%), Gaps = 23/346 (6%)
Query: 141 DKCEETLFKRKEIINWFESLMSQEKGISTKTLT-----MKIKEFNAENDLLKSSLDQLRT 195
D+ EE L K KE + + + + G ++ LT +++KE + E LK +
Sbjct: 867 DEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENA 926
Query: 196 EFL-KEINDIIDCLRKNANETMAL-QLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYA 253
FL K I D+ ++ E + KEL LSDL + Q A
Sbjct: 927 SFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERA 986
Query: 254 NRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARS-----ESW 308
+D+L A + ++ + +L ++A++ ++
Sbjct: 987 TSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAM 1046
Query: 309 SLERTVXXXXXXXXXXXEDFDQELNKLTQSI----KDNTTHLEDIALAREKL----QSXX 360
+ + ED Q KL + ++N ++E++ ++E L Q
Sbjct: 1047 QIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKME 1106
Query: 361 XXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDL 420
A+ KS + + N+ KL E + D + + L+E L L
Sbjct: 1107 EFRKEIETLKQAAAQKS-QQLSALQEENV-KLAEELGRSRDEVTSHQKLEEERSVLNNQL 1164
Query: 421 LESELRVKDLVRELDEKESILETKQCVQKELESTK-TDLEHRKTEI 465
LE + R +++ DE+++ L+ + L + K +LE + E+
Sbjct: 1165 LEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEV 1210
>BC112337-1|AAI12338.1| 1306|Homo sapiens kinectin 1 (kinesin
receptor) protein.
Length = 1306
Score = 44.8 bits (101), Expect = 0.001
Identities = 76/353 (21%), Positives = 147/353 (41%), Gaps = 30/353 (8%)
Query: 276 KDR-LSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNK 334
KD+ + + E L + +R+ E L+ ++ ++ L+ V EL K
Sbjct: 612 KDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAA-HELEK 670
Query: 335 LTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIE 394
+ QS+ + I L E+LQ + NK++K ++ ++
Sbjct: 671 MQQSVYVKD---DKIRLLEEQLQHEISNKMEEFKILN-DQNKALKSEVQKLQTLVS---- 722
Query: 395 IEKKYNDSIEE-KKTLQENIDDLRT--DLLESELRVKDLVRELDEKESILETKQCVQKEL 451
E+ D +E+ +K +QE + L+T +LLE+ L ++ +E +E +I + KE+
Sbjct: 723 -EQPNKDVVEQMEKCIQEKDEKLKTVEELLETGL-IQVATKE-EELNAIRTENSSLTKEV 779
Query: 452 ESTKT---DLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXX 508
+ K D + +EE K+++ EK +I ++ L E + +
Sbjct: 780 QDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAE--LLKVANKEKTVQLSITS 837
Query: 509 XXXXXXXXXXXRESQM---KSYYEE----LMNLKNQITQLREFGAFDNLNDVGNMINQQR 561
+E QM K+ EE L N + L+E ++L + Q
Sbjct: 838 KVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEEN--ESLKAHVQEVAQHN 895
Query: 562 DKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEE 614
K + EE + L+ KENE+KRL + E+E L+ K + ++ + ++ +
Sbjct: 896 LKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENK 948
Score = 40.3 bits (90), Expect = 0.023
Identities = 101/521 (19%), Positives = 204/521 (39%), Gaps = 39/521 (7%)
Query: 2 KQEELEIQQNQTDGCLYEDLNEQESITSESHK--ITKLKTVWQEKMVTFEKSKKELEDRQ 59
K EE +I +Q E Q ++ + +K + +++ QEK + ++ LE
Sbjct: 696 KMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGL 755
Query: 60 NQVMELYASLRNTHRKMKLLGQKVNLPSAEELHIMNVAKLSPEQLLQLC--AGGEPKALE 117
QV L + L ++V A++ ++ A L E+L ++ G+ K++E
Sbjct: 756 IQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLV-EELKKVIHEKDGKIKSVE 814
Query: 118 HSTLDNKVTFDVNKLLNIPNSLVDKCEE--TLFKRKEI-INWFESLMSQEKGISTKTLTM 174
L+ ++ NK + S+ K +E L K KE +N ++++ +EK
Sbjct: 815 E-LLEAELLKVANKEKTVQLSITSKVQELQNLLKGKEEQMNTMKAVL-EEKEKDLANTGK 872
Query: 175 KIKEFNAENDLLKSSLDQLRTEFLKEIN------DIIDCLRKNANETMALQLRTKELSCA 228
+++ EN+ LK+ + ++ LKE + ++ L++ NE L+ KE
Sbjct: 873 WLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESD 932
Query: 229 LS-------DLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXXSIMK----- 276
LS D+ +N + QI + I
Sbjct: 933 LSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNEL 992
Query: 277 DRLSRA-EHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKL 335
D L A EHQ K N + + A+E S L+ V E + E ++
Sbjct: 993 DSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEV 1052
Query: 336 TQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEI 395
+ + + +++ E L S S + + K + + L+++
Sbjct: 1053 LKKLFPKVSVPSNLSYG-EWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQL 1111
Query: 396 E-KKYNDSIEE--------KKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQC 446
E +KY + E ++++++ + + + ES +K + E LE +
Sbjct: 1112 ECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRS 1171
Query: 447 VQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLS 487
K++E+ + + EH + E+E+ + E+ ELK++L+
Sbjct: 1172 ENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKAQLN 1212
Score = 32.7 bits (71), Expect = 4.6
Identities = 47/237 (19%), Positives = 89/237 (37%), Gaps = 15/237 (6%)
Query: 379 KDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKE 438
+ ++ +M IA L + D++ E+ + L + LV EL EK
Sbjct: 409 QQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYA--RLVNELTEKT 466
Query: 439 SILETKQCVQKELESTKTDL-------EHRKTEIEEYKRLLFEKGEEIDE-LKSKLSTEK 490
L+ ++ +K E T L E R E++ Y R + E + L+SK ++
Sbjct: 467 GKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKE 526
Query: 491 AIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNL 550
++ ES+ K +E +L+ Q+ + E + L
Sbjct: 527 --NEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKE-ESLQMQVQDILEQN--EAL 581
Query: 551 NDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK 607
+ Q + EE + + K+ +IK+ +S+ + L KE+E+K
Sbjct: 582 KAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELK 638
>AL360170-2|CAH70404.1| 1235|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1235
Score = 44.8 bits (101), Expect = 0.001
Identities = 24/88 (27%), Positives = 52/88 (59%), Gaps = 7/88 (7%)
Query: 553 VGNMINQQRDKLF-----ELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK 607
+ + + QQR+++F E+ ++ +YD++++ E + K+ +E + EQEH +++ +
Sbjct: 848 LNSKLQQQREQIFRRFEQEMMSKKRQYDQEIENLEKQQKQTIERL-EQEHTNRLRDEAKR 906
Query: 608 MLNEKEEEHMNIINLLHN-KLELRNEAD 634
+ E+E+E N+L N K E+ NE +
Sbjct: 907 IKGEQEKELSKFQNMLKNRKKEVINEVE 934
>AL138761-2|CAI12395.1| 1235|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1235
Score = 44.8 bits (101), Expect = 0.001
Identities = 24/88 (27%), Positives = 52/88 (59%), Gaps = 7/88 (7%)
Query: 553 VGNMINQQRDKLF-----ELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK 607
+ + + QQR+++F E+ ++ +YD++++ E + K+ +E + EQEH +++ +
Sbjct: 848 LNSKLQQQREQIFRRFEQEMMSKKRQYDQEIENLEKQQKQTIERL-EQEHTNRLRDEAKR 906
Query: 608 MLNEKEEEHMNIINLLHN-KLELRNEAD 634
+ E+E+E N+L N K E+ NE +
Sbjct: 907 IKGEQEKELSKFQNMLKNRKKEVINEVE 934
>AK090540-1|BAC03473.1| 373|Homo sapiens protein ( Homo sapiens
cDNA FLJ33221 fis, clone ASTRO2000653, moderately
similar to Homo sapiens hook1 protein (HOOK1) mRNA. ).
Length = 373
Score = 44.8 bits (101), Expect = 0.001
Identities = 66/336 (19%), Positives = 138/336 (41%), Gaps = 15/336 (4%)
Query: 278 RLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQELNKLTQ 337
+ + A QL+T +VV+L+ L + ++ L+ ++ D+ L
Sbjct: 15 KANAARSQLETYKRQVVELQNRLSEESKKADKLDFEYKRLKEKVDSLQKEKDR-LRTERD 73
Query: 338 SIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIA---KLIE 394
S+K+ L + +L + + + + E + + K+++
Sbjct: 74 SLKETIEELRCVQAQEGQLTTQGLMPLGSQESSDSLAAEIVTPEIREKLIRLQHENKMLK 133
Query: 395 IEKKYNDSIEEKKTLQENIDD--LRTDLLESELRVKDLVRELDEKESILETKQCVQKELE 452
+ ++ +D+ E+ LQ +DD LR + LE+E R+ + + L E +S +E Q ++
Sbjct: 134 LNQEGSDN-EKIALLQSLLDDANLRKNELETENRLVN--QRLLEVQSQVEELQKSLQDQG 190
Query: 453 STKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXX 512
S D K ++EE+ L E +EL+ K + + ++
Sbjct: 191 SKAEDSVLLKKKLEEHLEKLHEAN---NELQKKRAIIEDLEPRFNNSSLKIEELQEALRK 247
Query: 513 XXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQE 572
E + K Y E+ ++ + + GA + + N + Q+RD+LF ++
Sbjct: 248 KEEEMKQMEERYKKYLEKAKSVIRTLDPKQNQGAAPEIQALKNQL-QERDRLFH--SLEK 304
Query: 573 EYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKM 608
EY++ +E E K +V + L+KK E ++
Sbjct: 305 EYEKTKSQREMEEKYIVSAWYNMGMTLHKKAAEDRL 340
Score = 33.9 bits (74), Expect = 2.0
Identities = 43/219 (19%), Positives = 100/219 (45%), Gaps = 14/219 (6%)
Query: 421 LESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIE-EYKRLLFEKGEEI 479
+++ + +++ +R+ + S LET + EL++ ++ + +++ EYKRL EK + +
Sbjct: 3 VQNTVSLEEELRKANAARSQLETYKRQVVELQNRLSEESKKADKLDFEYKRLK-EKVDSL 61
Query: 480 DELKSKLSTEK-AIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELM--NLKN 536
+ K +L TE+ ++K+ +ES S E++ ++
Sbjct: 62 QKEKDRLRTERDSLKETIEELRCVQAQEGQLTTQGLMPLGSQESS-DSLAAEIVTPEIRE 120
Query: 537 QITQLREFGAFDNLNDVGN------MINQQRDKLFELTKRQEEYDEKLQTKE-NEIKRLV 589
++ +L+ LN G+ ++ D L K + E + +L + E++ V
Sbjct: 121 KLIRLQHENKMLKLNQEGSDNEKIALLQSLLDDA-NLRKNELETENRLVNQRLLEVQSQV 179
Query: 590 ESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
E + + K ++ +L +K EEH+ ++ +N+L+
Sbjct: 180 EELQKSLQDQGSKAEDSVLLKKKLEEHLEKLHEANNELQ 218
>AF273048-1|AAG34908.1| 1235|Homo sapiens CTCL tumor antigen se20-9
protein.
Length = 1235
Score = 44.8 bits (101), Expect = 0.001
Identities = 24/88 (27%), Positives = 52/88 (59%), Gaps = 7/88 (7%)
Query: 553 VGNMINQQRDKLF-----ELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK 607
+ + + QQR+++F E+ ++ +YD++++ E + K+ +E + EQEH +++ +
Sbjct: 848 LNSKLQQQREQIFRRFEQEMMSKKRQYDQEIENLEKQQKQTIERL-EQEHTNRLRDEAKR 906
Query: 608 MLNEKEEEHMNIINLLHN-KLELRNEAD 634
+ E+E+E N+L N K E+ NE +
Sbjct: 907 IKGEQEKELSKFQNMLKNRKKEVINEVE 934
>Z75311-1|CAA99729.1| 1318|Homo sapiens RAD50 homologue hsRAD50
protein.
Length = 1318
Score = 44.4 bits (100), Expect = 0.001
Identities = 53/207 (25%), Positives = 91/207 (43%), Gaps = 18/207 (8%)
Query: 277 DRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXX---XXXEDFDQE-- 331
+ L + Q+ TN++R QLE + +E SL R + E F QE
Sbjct: 874 NELKSEKLQISTNLQRRQQLEEQTVELSTEVQSLYREIKDAKEQVSPLETTLEKFQQEKE 933
Query: 332 --LNKLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNI 389
+NK S K L DI +EK+++ + +K + E+N I
Sbjct: 934 ELINKKNTSNKIAQDKLNDI---KEKVKNIHGYMKDIENHIQDGKDDYMKQKETELNKVI 990
Query: 390 AKLIEIEKKYNDSIEEKKTLQENID--DLRTDLLESELRVKDLVRELDEKESILETKQCV 447
A+L E EK E+ + ++++ID ++ L+ L ++ EL E E E KQ +
Sbjct: 991 AQLSECEKHKEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRNEELKEVEE--EGKQHL 1048
Query: 448 QK--ELESTKTDLEHRKTE--IEEYKR 470
++ +++ + EH+K E I+ KR
Sbjct: 1049 KEMGQMQVLQMKSEHQKLEENIDNIKR 1075
Score = 42.3 bits (95), Expect = 0.006
Identities = 46/267 (17%), Positives = 112/267 (41%), Gaps = 16/267 (5%)
Query: 374 YNKSIKDMKHEMNLNIAKL--IEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLV 431
+ +KD++ ++ AKL I++++ +EK+ Q +D + + + EL K L+
Sbjct: 804 FQMELKDVERKIAQQAAKLQGIDLDRTVQQVNQEKQEKQHKLDTVSSKI---ELNRK-LI 859
Query: 432 RELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKA 491
+ D++E I K EL+S K + ++ + E E+ L ++ K
Sbjct: 860 Q--DQQEQIQHLKSTTN-ELKSEKLQISTNLQRRQQLEEQTVELSTEVQSLYREIKDAKE 916
Query: 492 -IKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREF---GAF 547
+ + + ++ E++ N+ + + G
Sbjct: 917 QVSPLETTLEKFQQEKEELINKKNTSNKIAQDKLNDIKEKVKNIHGYMKDIENHIQDGKD 976
Query: 548 DNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEI--KRLVESMTEQEHVLNKKEKE 605
D + +N+ +L E K +E+ +E ++ +I +++ E + L K+ +E
Sbjct: 977 DYMKQKETELNKVIAQLSECEKHKEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRNEE 1036
Query: 606 IKMLNEKEEEHMNIINLLHNKLELRNE 632
+K + E+ ++H+ + + L++++E
Sbjct: 1037 LKEVEEEGKQHLKEMGQM-QVLQMKSE 1062
Score = 39.5 bits (88), Expect = 0.040
Identities = 93/484 (19%), Positives = 185/484 (38%), Gaps = 27/484 (5%)
Query: 128 DVNKLLNIPNSLVDKCEETLFKRKEIINWFESL--MSQEKGISTKTLTMKIKEFNAENDL 185
D N L+ +L K +E +F I E+L + Q +G + M++K +
Sbjct: 167 DSNWPLSEGKALKQKFDE-IFSATRYIKALETLRQVRQTQGQKVEEYQMELKYLKQYKEK 225
Query: 186 LKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHS 245
DQ+ T ++ + ++ NE L+ R KE+ LS + ++ +I +
Sbjct: 226 ACEIRDQI-TSKEAQLTSSKEIVKSYENELDPLKNRLKEIEHNLSKI----MKLDNEIKA 280
Query: 246 GDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQLEAALEQARS 305
D + ++ + D + ++ ++V LE+
Sbjct: 281 LDSRKKQMEKDNSELEEKMEKVFQGTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNK 340
Query: 306 ESWSL--ERTVXXXXXXXXXXXEDFDQELNKLTQS-IKDNTTHLEDIALAREKLQSXXXX 362
ES L E++ D QE + S I+ T LE R
Sbjct: 341 ESRLLNQEKSELLVEQGRLQLQADRHQEHIRARDSLIQSLATQLELDGFERGPFSERQIK 400
Query: 363 XXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLL- 421
K MN + A+ +++K D I +KKT I +L++++L
Sbjct: 401 NFHKLVRERQE--GEAKTANQLMN-DFAEKETLKQKQIDEIRDKKTGLGRIIELKSEILS 457
Query: 422 --ESELR-VKDLVRELD-EKESILETKQ-CVQKELESTKTDLEHRKTEIEEYK-RLLFEK 475
++EL+ VK +++L+ + ILE Q ++ E E +K + + + +E K ++ +
Sbjct: 458 KKQNELKNVKYELQQLEGSSDRILELDQELIKAERELSKAE---KNSNVETLKMEVISLQ 514
Query: 476 GEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLK 535
E+ D ++ ++ ++ + R+ + + + +EL +L
Sbjct: 515 NEKADLDRTLRKLDQEMEQLNHHTTTRTQMEMLTKDKADKDEQIRKIKSR-HSDELTSLL 573
Query: 536 NQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQ 595
++ D L+ INQ RD+L +L K ++ NE++R E ++
Sbjct: 574 GYFPNKKQLE--DWLHSKSKEINQTRDRLAKLNKELASSEQNKNHINNELERKEEQLSSY 631
Query: 596 EHVL 599
E L
Sbjct: 632 EDKL 635
Score = 32.3 bits (70), Expect = 6.1
Identities = 42/238 (17%), Positives = 103/238 (43%), Gaps = 28/238 (11%)
Query: 409 LQENIDDLRTDL---------LESELRVKDLVRE-----LDEKESILETKQC----VQKE 450
LQE I DL++ L ESEL+ K+ R+ ++SI++ K+ ++ +
Sbjct: 700 LQEAISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPMRQSIIDLKEKEIPELRNK 759
Query: 451 LESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLST-------EKAIKDIXXXXXXXX 503
L++ D++ K +IEE + LL E + K L+ + +KD+
Sbjct: 760 LQNVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQA 819
Query: 504 XXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDK 563
+E Q K + + ++ K ++ + + + + + N+ + +
Sbjct: 820 AKLQGIDLDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKSTTNELKSE 879
Query: 564 LFELT---KRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMN 618
+++ +R+++ +E+ E++ L + + + ++ E ++ +++EE +N
Sbjct: 880 KLQISTNLQRRQQLEEQTVELSTEVQSLYREIKDAKEQVSPLETTLEKFQQEKEELIN 937
>X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for
embryonic myosin heavy chain. ).
Length = 1940
Score = 44.4 bits (100), Expect = 0.001
Identities = 81/459 (17%), Positives = 174/459 (37%), Gaps = 21/459 (4%)
Query: 186 LKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHS 245
+K L TE KE+ + + +K +E + + KEL L L + +++ Q+ +
Sbjct: 837 IKPLLKSAETE--KEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQA 894
Query: 246 GDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQ---LEAALEQ 302
+ A +K+ RAE + + N E + LE +
Sbjct: 895 ESENLLDAEERCDQLIKAKFQLEAK----IKEVTERAEDEEEINAELTAKKRKLEDECSE 950
Query: 303 ARSESWSLERT---VXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSX 359
+ + LE T V ++ +EL+ L ++I T + + A ++
Sbjct: 951 LKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDD 1010
Query: 360 XXXXXXXXXXXSASYNK---SIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDL 416
+ + +K ++D++ + +++E+ + K QE+I DL
Sbjct: 1011 LQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDL 1070
Query: 417 RTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKG 476
D + + R+K E + +S +E +Q + + + +L+ R E+EE + E+
Sbjct: 1071 ENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEE--EIEAERA 1128
Query: 477 EEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKN 536
K + + ++++ + E + +
Sbjct: 1129 TRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEA 1188
Query: 537 QITQLREFGAFDNLNDVGNMI-NQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQ 595
+ LR+ A D++ ++G I N QR K +L K + E+ ++ + ++ + +S
Sbjct: 1189 MVATLRKKHA-DSVAELGEQIDNLQRVKQ-KLEKEKSEFKLEIDDLSSSMESVSKSKANL 1246
Query: 596 EHVLNKKEKEIKMLNEKEEE-HMNIINLLHNKLELRNEA 633
E + E ++ K EE ++ L K L+ EA
Sbjct: 1247 EKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEA 1285
Score = 36.3 bits (80), Expect = 0.37
Identities = 32/162 (19%), Positives = 69/162 (42%), Gaps = 10/162 (6%)
Query: 334 KLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLI 393
K S+ + ++++ ++KL+ S+S +S+ K N+ K+
Sbjct: 1196 KHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSM-ESVSKSK----ANLEKIC 1250
Query: 394 E-IEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESIL----ETKQCVQ 448
+E + +++ + + +Q ++ +L T + +L R+L+EKESI+ +KQ
Sbjct: 1251 RTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFT 1310
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEK 490
++ E K LE L + D L+ + E+
Sbjct: 1311 QQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQ 1352
Score = 33.1 bits (72), Expect = 3.5
Identities = 61/349 (17%), Positives = 130/349 (37%), Gaps = 23/349 (6%)
Query: 291 ERVVQLEAALEQARSESWSLERT------VXXXXXXXXXXXEDFDQELNKLTQSIKDNTT 344
E +LEA+L+++RS S L + ++ +QE+ LT+ I +N
Sbjct: 1463 ESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGK 1522
Query: 345 HLEDIALAREKLQSXXXXXXXXXXXXSASY-NKSIKDMKHEMNLNIAKLIEIEKKYNDSI 403
+ ++ +R++++ A+ ++ K ++ ++ L K EI++K +
Sbjct: 1523 TIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVK-SEIDRKIAEKD 1581
Query: 404 EEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEH-RK 462
EE + L+ N RT E L E+ + + K+ ++ +L + L H +
Sbjct: 1582 EEIEQLKRNYQ--RT----VETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANR 1635
Query: 463 TEIEEYKRLLFEKGEEID---ELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXX 519
E K L +G+ D L L ++ +K+
Sbjct: 1636 QAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQ 1695
Query: 520 RESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQ 579
E K +EL++ ++ L N + + + D L +L E+ +
Sbjct: 1696 TERARKLAEQELLDSNERVQLLHT----QNTSLIHTKKKLETD-LMQLQSEVEDASRDAR 1750
Query: 580 TKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
E + K+ + L K++ L ++ + L ++L+
Sbjct: 1751 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLD 1799
>X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 AA)
protein.
Length = 1167
Score = 44.4 bits (100), Expect = 0.001
Identities = 81/459 (17%), Positives = 174/459 (37%), Gaps = 21/459 (4%)
Query: 186 LKSSLDQLRTEFLKEINDIIDCLRKNANETMALQLRTKELSCALSDLNTQNAEMRKQIHS 245
+K L TE KE+ + + +K +E + + KEL L L + +++ Q+ +
Sbjct: 64 IKPLLKSAETE--KEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQA 121
Query: 246 GDHHRPYANRNXXXXXXXXXXXXXXXXSIMKDRLSRAEHQLKTNVERVVQ---LEAALEQ 302
+ A +K+ RAE + + N E + LE +
Sbjct: 122 ESENLLDAEERCDQLIKAKFQLEAK----IKEVTERAEDEEEINAELTAKKRKLEDECSE 177
Query: 303 ARSESWSLERT---VXXXXXXXXXXXEDFDQELNKLTQSIKDNTTHLEDIALAREKLQSX 359
+ + LE T V ++ +EL+ L ++I T + + A ++
Sbjct: 178 LKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDD 237
Query: 360 XXXXXXXXXXXSASYNK---SIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDL 416
+ + +K ++D++ + +++E+ + K QE+I DL
Sbjct: 238 LQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDL 297
Query: 417 RTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKG 476
D + + R+K E + +S +E +Q + + + +L+ R E+EE + E+
Sbjct: 298 ENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEE--EIEAERA 355
Query: 477 EEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKN 536
K + + ++++ + E + +
Sbjct: 356 TRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEA 415
Query: 537 QITQLREFGAFDNLNDVGNMI-NQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQ 595
+ LR+ A D++ ++G I N QR K +L K + E+ ++ + ++ + +S
Sbjct: 416 MVATLRKKHA-DSVAELGEQIDNLQRVKQ-KLEKEKSEFKLEIDDLSSSMESVSKSKANL 473
Query: 596 EHVLNKKEKEIKMLNEKEEE-HMNIINLLHNKLELRNEA 633
E + E ++ K EE ++ L K L+ EA
Sbjct: 474 EKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEA 512
Score = 36.3 bits (80), Expect = 0.37
Identities = 32/162 (19%), Positives = 69/162 (42%), Gaps = 10/162 (6%)
Query: 334 KLTQSIKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLI 393
K S+ + ++++ ++KL+ S+S +S+ K N+ K+
Sbjct: 423 KHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSM-ESVSKSK----ANLEKIC 477
Query: 394 E-IEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESIL----ETKQCVQ 448
+E + +++ + + +Q ++ +L T + +L R+L+EKESI+ +KQ
Sbjct: 478 RTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFT 537
Query: 449 KELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEK 490
++ E K LE L + D L+ + E+
Sbjct: 538 QQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQ 579
Score = 36.3 bits (80), Expect = 0.37
Identities = 62/349 (17%), Positives = 131/349 (37%), Gaps = 23/349 (6%)
Query: 291 ERVVQLEAALEQARSESWSLERT------VXXXXXXXXXXXEDFDQELNKLTQSIKDNTT 344
E +LEA+L+++RS S L + ++ +QE+ LT+ I +N
Sbjct: 690 ESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGK 749
Query: 345 HLEDIALAREKLQSXXXXXXXXXXXXSASY-NKSIKDMKHEMNLNIAKLIEIEKKYNDSI 403
+ ++ +R++++ A+ ++ K ++ ++ L K EI++K +
Sbjct: 750 TIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVK-SEIDRKIAEKD 808
Query: 404 EEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEH-RK 462
EE + L+ N RT E L E+ + + K+ ++ +L + L H +
Sbjct: 809 EEIEQLKRNYQ--RT----VETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANR 862
Query: 463 TEIEEYKRLLFEKGEEID---ELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXX 519
E K L +G+ D L L T++ +K+
Sbjct: 863 QAAETLKHLRSVQGQLKDTQLHLDDALQTQEDLKEQLAIVERRANLLQAEVEELRATLEQ 922
Query: 520 RESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQ 579
E K +EL++ ++ L N + + + D L +L E+ +
Sbjct: 923 TERARKLAEQELLDSNERVQLLHT----QNTSLIHTKKKLETD-LMQLQSEVEDASRDAR 977
Query: 580 TKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
E + K+ + L K++ L ++ + L ++L+
Sbjct: 978 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLD 1026
>BC047324-1|AAH47324.1| 1217|Homo sapiens structural maintenance of
chromosomes 3 protein.
Length = 1217
Score = 44.4 bits (100), Expect = 0.001
Identities = 57/238 (23%), Positives = 99/238 (41%), Gaps = 16/238 (6%)
Query: 384 EMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVREL----DEKES 439
E+N AKL E+ K S E+ + L++ D R + + E +V++L ++ +EKE
Sbjct: 231 ELNETRAKLDELSAKRETSGEKSRQLRDAQQDARDKMEDIERQVRELKTKISAMKEEKEQ 290
Query: 440 ILETKQCVQKE---LESTKTDLEHRKT-EIEEYKRLLFEKG---EEIDELKSKLS-TEKA 491
+ +Q K+ LE DL+ E+ KRLL E+ E+I+E + +L+ TE
Sbjct: 291 LSAERQEQIKQRTKLELKAKDLQDELAGNSEQRKRLLKERQKLLEKIEEKQKELAETEPK 350
Query: 492 IKDI--XXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDN 549
+ R SQ S E +K ++ L + D
Sbjct: 351 FNSVKEKEERGIARLAQATQERTDLYAKQGRGSQFTSKEERDKWIKKELKSLDQ-AINDK 409
Query: 550 LNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK 607
+ + D K E+Y+ KL NE+K VE + + + + K+ E++
Sbjct: 410 KRQIAAIHKDLEDTEANKEKNLEQYN-KLDQDLNEVKARVEELDRKYYEVKNKKDELQ 466
>BC043398-1|AAH43398.1| 805|Homo sapiens CEP290 protein protein.
Length = 805
Score = 44.4 bits (100), Expect = 0.001
Identities = 69/389 (17%), Positives = 158/389 (40%), Gaps = 34/389 (8%)
Query: 280 SRAEHQLKTNVERVVQLEAALEQARSESWSLE-RTVXXXXXXXXXXXEDFDQELNKLTQS 338
++ E+QLKT +V++LE LE A+ + + R + E D+EL + +
Sbjct: 81 AKFENQLKT---KVMKLENELEMAQQSAGGRDTRFLRNEICQLEKQLEQKDRELEDMEKE 137
Query: 339 IKDNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNIAKLIEIEKK 398
++ E +AL E+ ++ NK +K ++ +I I+ +K+
Sbjct: 138 LEKEKKVNEQLALRNEEAENENSKLRRE--------NKRLKKKNEQLCQDI---IDYQKQ 186
Query: 399 YNDSIEEKKTLQENIDDLRTDLLESE---LRVKDLVRELDEKESILETK-QCVQKELEST 454
+ E + + D R+ L + ++ D ++ L E +E + Q ++K LE +
Sbjct: 187 IDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEES 246
Query: 455 KTDLEHRKTEIEEYKRLLFEKGEEIDELKSK-----LSTEKA---IKDIXXXXXXXXXXX 506
++E E K ++ + ID+LK + L ++ +K
Sbjct: 247 VQEMEKMTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQELTDLLKSKNEEDDPIMVAV 306
Query: 507 XXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFE 566
++ ++ Y + L NL+ ++ + N+ + I ++ ++
Sbjct: 307 NAKVEEWKLILSSKDDEIIEYQQMLHNLREKLKNAQLDADKSNVMALQQGIQERDSQIKM 366
Query: 567 LTKRQEEYDEKLQTK-------ENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNI 619
LT++ E+Y ++++ +NE++R + T + K + + +L EK +E
Sbjct: 367 LTEQVEQYTKEMEKNTCIIEDLKNELQRNKGASTLSQQTHMKIQSTLDILKEKTKEAERT 426
Query: 620 INLLHNKLELRNEADIDVIITLAKYKKSL 648
L +++ ++ + L Y+ +
Sbjct: 427 AELAEADAREKDKELVEALKRLKDYESGV 455
Score = 33.1 bits (72), Expect = 3.5
Identities = 57/312 (18%), Positives = 126/312 (40%), Gaps = 22/312 (7%)
Query: 326 EDFDQELNKLTQSIKDNTTHLE-DIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHE 384
E +E K +K LE ++ +A+ QS K ++ E
Sbjct: 74 EKAGEEQAKFENQLKTKVMKLENELEMAQ---QSAGGRDTRFLRNEICQLEKQLEQKDRE 130
Query: 385 MNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETK 444
+ ++ K +E EKK N+ + + EN + S+LR ++ R + E + +
Sbjct: 131 LE-DMEKELEKEKKVNEQLALRNEEAENEN--------SKLR-RENKRLKKKNEQLCQDI 180
Query: 445 QCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXX 504
QK+++S K L R+ E +Y+ L +K E+ + ++ T +
Sbjct: 181 IDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMR 240
Query: 505 XXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAF--DNLNDVGNMINQQRD 562
++MK+ + N+ +Q+ + + L D+ N++ D
Sbjct: 241 KNLEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQELTDLLKSKNEEDD 300
Query: 563 KLF-ELTKRQEEYDEKLQTKENEI---KRLVESMTE--QEHVLNKKEKEIKMLNEKEEEH 616
+ + + EE+ L +K++EI ++++ ++ E + L+ + + L + +E
Sbjct: 301 PIMVAVNAKVEEWKLILSSKDDEIIEYQQMLHNLREKLKNAQLDADKSNVMALQQGIQER 360
Query: 617 MNIINLLHNKLE 628
+ I +L ++E
Sbjct: 361 DSQIKMLTEQVE 372
>AY517555-1|AAT44528.1| 941|Homo sapiens hypothetical
rhabdomyosarcoma antigen MU-RMS-40.3 protein.
Length = 941
Score = 44.4 bits (100), Expect = 0.001
Identities = 73/445 (16%), Positives = 159/445 (35%), Gaps = 11/445 (2%)
Query: 213 NETMALQLRTKELSCALSDLNTQNAEMRKQIHSGDHHRPYANRNXXXXXXXXXXXXXXXX 272
++ A + + L+ S L Q ++ + R RN
Sbjct: 10 DDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESIL 69
Query: 273 SIMKDRLSRAEHQLKTNVERVVQLEAALEQARSESWSLERTVXXXXXXXXXXXEDFDQEL 332
+ D+ + + +LK QL++ +E ++ ++ + E+ + E
Sbjct: 70 DLENDK-QQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAER 128
Query: 333 NKLTQSIK---DNTTHLEDIALAREKLQSXXXXXXXXXXXXSASYNKSIKDMKHEMNLNI 389
++ K D LE+++ E+ A + K +D++ +
Sbjct: 129 ATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHE 188
Query: 390 AKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQK 449
A + + KK+ DS+ E L E ID+L+ + E + E+D+ S +E+ +
Sbjct: 189 AMVATLRKKHADSVAE---LGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKA 245
Query: 450 ELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXX 509
LE LE + +E + E+ KS+L TE ++
Sbjct: 246 NLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAG--ELSRQLEEKESIVSQL 303
Query: 510 XXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTK 569
E ++K EE KN + + D + + ++++ EL +
Sbjct: 304 SRSKQAFTQQTE-ELKRQLEEENKAKNALAHALQSSRHD-CDLLREQYEEEQEGKAELQR 361
Query: 570 RQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLEL 629
+ + ++ + + TE+ KK + +E++ E +N K +
Sbjct: 362 ALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQ 421
Query: 630 RNEADIDVIITLAKYKKSLTLVLEK 654
R + +++ ++ + SL L+K
Sbjct: 422 RLQGEVEDLMVDVERANSLAAALDK 446
Score = 39.5 bits (88), Expect = 0.040
Identities = 65/284 (22%), Positives = 113/284 (39%), Gaps = 18/284 (6%)
Query: 396 EKKYNDSIEEKKTLQENIDDLRTDL-LESELRVKDLVRELDEKESILETKQCVQKELEST 454
E K N + K L++ ++DL + L E +LRV DL R + E L+ Q +LE+
Sbjct: 16 EDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRV-DLERNKRKLEGDLKLAQESILDLEND 74
Query: 455 KTDLEHR-KTEIEEYKRLLFEKGEEIDELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXX 513
K L+ R K + EY +L + + DE L +K IK++
Sbjct: 75 KQQLDERLKKKDFEYCQL---QSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATR 131
Query: 514 XXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEE 573
E Q Y EL L +L E G + +N++R+ E K + +
Sbjct: 132 AKT----EKQRSDYARELEELSE---RLEEAG---GVTSTQIELNKKREA--EFLKLRRD 179
Query: 574 YDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLELRNEA 633
+E E + L + + L ++ ++ + +K E+ + L + L E+
Sbjct: 180 LEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMES 239
Query: 634 DIDVIITLAKYKKSLTLVLEKMSISNRVLKCSLLGVVTQSRTLR 677
L K ++L L + N ++ SL + TQ L+
Sbjct: 240 VSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQ 283
Score = 33.1 bits (72), Expect = 3.5
Identities = 61/349 (17%), Positives = 130/349 (37%), Gaps = 23/349 (6%)
Query: 291 ERVVQLEAALEQARSESWSLERT------VXXXXXXXXXXXEDFDQELNKLTQSIKDNTT 344
E +LEA+L+++RS S L + ++ +QE+ LT+ I +N
Sbjct: 464 ESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGK 523
Query: 345 HLEDIALAREKLQSXXXXXXXXXXXXSASY-NKSIKDMKHEMNLNIAKLIEIEKKYNDSI 403
+ ++ +R++++ A+ ++ K ++ ++ L K EI++K +
Sbjct: 524 TIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVK-SEIDRKIAEKD 582
Query: 404 EEKKTLQENIDDLRTDLLESELRVKDLVRELDEKESILETKQCVQKELESTKTDLEH-RK 462
EE + L+ N RT E L E+ + + K+ ++ +L + L H +
Sbjct: 583 EEIEQLKRNYQ--RT----VETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANR 636
Query: 463 TEIEEYKRLLFEKGEEID---ELKSKLSTEKAIKDIXXXXXXXXXXXXXXXXXXXXXXXX 519
E K L +G+ D L L ++ +K+
Sbjct: 637 QAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQ 696
Query: 520 RESQMKSYYEELMNLKNQITQLREFGAFDNLNDVGNMINQQRDKLFELTKRQEEYDEKLQ 579
E K +EL++ ++ L N + + + D L +L E+ +
Sbjct: 697 TERARKLAEQELLDSNERVQLLHT----QNTSLIHTKKKLETD-LMQLQSEVEDASRDAR 751
Query: 580 TKENEIKRLVESMTEQEHVLNKKEKEIKMLNEKEEEHMNIINLLHNKLE 628
E + K+ + L K++ L ++ + L ++L+
Sbjct: 752 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLD 800
>AL359260-2|CAI16576.1| 1217|Homo sapiens structural maintenance of
chromosomes 3 protein.
Length = 1217
Score = 44.4 bits (100), Expect = 0.001
Identities = 57/238 (23%), Positives = 99/238 (41%), Gaps = 16/238 (6%)
Query: 384 EMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVREL----DEKES 439
E+N AKL E+ K S E+ + L++ D R + + E +V++L ++ +EKE
Sbjct: 231 ELNETRAKLDELSAKRETSGEKSRQLRDAQQDARDKMEDIERQVRELKTKISAMKEEKEQ 290
Query: 440 ILETKQCVQKE---LESTKTDLEHRKT-EIEEYKRLLFEKG---EEIDELKSKLS-TEKA 491
+ +Q K+ LE DL+ E+ KRLL E+ E+I+E + +L+ TE
Sbjct: 291 LSAERQEQIKQRTKLELKAKDLQDELAGNSEQRKRLLKERQKLLEKIEEKQKELAETEPK 350
Query: 492 IKDI--XXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREFGAFDN 549
+ R SQ S E +K ++ L + D
Sbjct: 351 FNSVKEKEERGIARLAQATQERTDLYAKQGRGSQFTSKEERDKWIKKELKSLDQ-AINDK 409
Query: 550 LNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLVESMTEQEHVLNKKEKEIK 607
+ + D K E+Y+ KL NE+K VE + + + + K+ E++
Sbjct: 410 KRQIAAIHKDLEDTEANKEKNLEQYN-KLDQDLNEVKARVEELDRKYYEVKNKKDELQ 466
>AK055217-1|BAB70876.1| 688|Homo sapiens protein ( Homo sapiens
cDNA FLJ30655 fis, clone DFNES2000268, weakly similar to
MYOSIN HEAVY CHAIN, STRIATED MUSCLE. ).
Length = 688
Score = 44.4 bits (100), Expect = 0.001
Identities = 60/290 (20%), Positives = 118/290 (40%), Gaps = 27/290 (9%)
Query: 374 YNKSIKDMKHEMNLNIAKLIEIEKKYNDSIEEKKTLQENIDDLRTDLLESELRVKDLVRE 433
Y K + +MK ++ I + + + D++E+K ++ TD+ + V++L +
Sbjct: 77 YQKQVGEMKLQLENVIKENERLHSELKDAVEKKLEAFPLGTEVGTDIYADDETVRNLQEQ 136
Query: 434 LD----EKESILETKQCVQKELESTKTDLEHRKTEIEEYKRLLFEKGEEIDELKSKLSTE 489
L EK +E Q V +EL+ + TE + + +FE ++ D+L +
Sbjct: 137 LQLANQEKTQAVELWQTVSQELDRLHKLYQEHMTEAQIH---VFESQKQKDQL---FDFQ 190
Query: 490 KAIKDIXXXXXXXXXXXXXXXXXXXXXXXXRESQMKSYYEELMNLKNQITQLREF-GAFD 548
+ K + E K + + L+ + ++ E +
Sbjct: 191 QLTKQLHVTNENMEVTNQQFLKTVTEQSVIIEQLRKKLRQAKLELRVAVAKVEELTNVTE 250
Query: 549 NLNDVGNMINQQRDKLFELTKRQEEYDEKLQTKENEIKRLV-----------ESMTEQEH 597
+L G M +++D + R+E D +LQ ++ IK+L + TE H
Sbjct: 251 DLQ--GQMKKKEKD-VVSAHGREEASDRRLQQLQSSIKQLEIRLCVTIQEANQLRTENTH 307
Query: 598 VLNKKEKEIK-MLNEKEEEHMNIINLLHNKLELRNEADIDVIITLAKYKK 646
L K+ +E++ NE E E I N ++L EA++ L + K+
Sbjct: 308 -LEKQTRELQAKCNELENERYEAIVRARNSMQLLEEANLQKSQALLEEKQ 356
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.311 0.128 0.335
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 77,180,745
Number of Sequences: 224733
Number of extensions: 2970956
Number of successful extensions: 29542
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 366
Number of HSP's successfully gapped in prelim test: 1158
Number of HSP's that attempted gapping in prelim test: 19793
Number of HSP's gapped (non-prelim): 9091
length of query: 706
length of database: 73,234,838
effective HSP length: 95
effective length of query: 611
effective length of database: 51,885,203
effective search space: 31701859033
effective search space used: 31701859033
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (21.8 bits)
S2: 69 (31.9 bits)
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