Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000891-TA|BGIBMGA000891-PA|IPR006201|Neurotransmitter-
gated ion-channel, IPR006028|Gamma-aminobutyric acid A receptor,
IPR001390|Gamma-aminobutyric-acid A receptor, alpha subunit,
IPR006202|Neurotransmitter-gated ion-channel ligand-binding,
IPR006029|Neurotransmitter-gated ion-channel transmembrane region
(539 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q4V4V5 Cluster: IP12579p; n=6; Endopterygota|Rep: IP125... 442 e-122
UniRef50_Q0GQQ6 Cluster: Cys-loop ligand-gated ion channel subun... 429 e-119
UniRef50_UPI00015B5C4C Cluster: PREDICTED: similar to GABA-gated... 302 2e-80
UniRef50_Q0GQR6 Cluster: GABA-gated ion channel; n=2; Apis melli... 301 2e-80
UniRef50_Q8WSF7 Cluster: GABA A receptor alpha subunit; n=1; Apl... 268 3e-70
UniRef50_Q6BET0 Cluster: Putative uncharacterized protein; n=2; ... 243 8e-63
UniRef50_P31644 Cluster: Gamma-aminobutyric acid receptor subuni... 241 2e-62
UniRef50_P48169 Cluster: Gamma-aminobutyric acid receptor subuni... 238 3e-61
UniRef50_P34903 Cluster: Gamma-aminobutyric acid receptor subuni... 234 5e-60
UniRef50_Q24352 Cluster: Gamma-aminobutyric acid receptor alpha-... 231 5e-59
UniRef50_Q25035 Cluster: GABA A/glycine receptor subunit; n=3; R... 227 6e-58
UniRef50_UPI0000E20C28 Cluster: PREDICTED: gamma-aminobutyric ac... 225 2e-57
UniRef50_Q99928 Cluster: Gamma-aminobutyric acid receptor subuni... 223 7e-57
UniRef50_O75311 Cluster: Glycine receptor subunit alpha-3 precur... 204 4e-51
UniRef50_P47870-2 Cluster: Isoform Long of P47870 ; n=22; Eumeta... 203 8e-51
UniRef50_O18276 Cluster: Gamma-aminobutyric acid receptor subuni... 203 1e-50
UniRef50_A2BGE6 Cluster: Glycine receptor, alpha 4b; n=5; Danio ... 198 4e-49
UniRef50_P78334 Cluster: Gamma-aminobutyric acid receptor subuni... 198 4e-49
UniRef50_P18505 Cluster: Gamma-aminobutyric acid receptor subuni... 196 1e-48
UniRef50_UPI00015B58ED Cluster: PREDICTED: similar to GABA-gated... 193 1e-47
UniRef50_Q2PMX5 Cluster: GABA receptor; n=1; Tetranychus urticae... 191 3e-47
UniRef50_A7SLK4 Cluster: Predicted protein; n=2; Nematostella ve... 189 2e-46
UniRef50_P25123 Cluster: Gamma-aminobutyric acid receptor subuni... 186 1e-45
UniRef50_A7SFG6 Cluster: Predicted protein; n=4; Nematostella ve... 185 3e-45
UniRef50_UPI00006A0B5C Cluster: Gamma-aminobutyric-acid receptor... 183 1e-44
UniRef50_UPI0000E4758B Cluster: PREDICTED: similar to GABA-gated... 182 2e-44
UniRef50_O14764 Cluster: Gamma-aminobutyric acid receptor subuni... 182 3e-44
UniRef50_UPI000065FF28 Cluster: Gamma-aminobutyric-acid receptor... 180 7e-44
UniRef50_Q08832 Cluster: Gamma-aminobutyric acid receptor subuni... 180 9e-44
UniRef50_P28476 Cluster: Gamma-aminobutyric acid receptor subuni... 178 3e-43
UniRef50_UPI00015B4D8A Cluster: PREDICTED: similar to glutamate-... 177 8e-43
UniRef50_UPI0000E47589 Cluster: PREDICTED: similar to gamma-amin... 176 1e-42
UniRef50_Q94900 Cluster: Glutamate-gated chloride channel precur... 176 1e-42
UniRef50_A7S5Y7 Cluster: Predicted protein; n=1; Nematostella ve... 175 2e-42
UniRef50_Q9UN88 Cluster: Gamma-aminobutyric acid receptor subuni... 175 2e-42
UniRef50_A7S763 Cluster: Predicted protein; n=1; Nematostella ve... 173 1e-41
UniRef50_P48167 Cluster: Glycine receptor subunit beta precursor... 173 1e-41
UniRef50_Q8MTJ9 Cluster: Ionotropic GABA receptor beta subunit 1... 172 2e-41
UniRef50_O17547 Cluster: GluClalpha2A protein; n=66; Chromadorea... 172 2e-41
UniRef50_A7SDF1 Cluster: Predicted protein; n=2; Nematostella ve... 172 2e-41
UniRef50_A7S8M2 Cluster: Predicted protein; n=2; Nematostella ve... 170 9e-41
UniRef50_A7SJ14 Cluster: Predicted protein; n=2; Nematostella ve... 169 1e-40
UniRef50_O00591 Cluster: Gamma-aminobutyric acid receptor subuni... 169 1e-40
UniRef50_Q9Y0I3 Cluster: Ionotropic GABA receptor subunit UNC-49... 169 2e-40
UniRef50_UPI0000D9B066 Cluster: PREDICTED: gamma-aminobutyric ac... 169 2e-40
UniRef50_A7RS31 Cluster: Predicted protein; n=1; Nematostella ve... 167 7e-40
UniRef50_Q4SKT9 Cluster: Chromosome undetermined SCAF14565, whol... 165 2e-39
UniRef50_A7SFV7 Cluster: Predicted protein; n=1; Nematostella ve... 164 6e-39
UniRef50_Q4S0E0 Cluster: Chromosome 2 SCAF14781, whole genome sh... 163 8e-39
UniRef50_O46123 Cluster: GBR-2A protein precursor; n=3; Chromado... 162 2e-38
UniRef50_A7S6R3 Cluster: Predicted protein; n=3; Nematostella ve... 160 7e-38
UniRef50_A7SVS1 Cluster: Predicted protein; n=5; Nematostella ve... 159 2e-37
UniRef50_A7SNP9 Cluster: Predicted protein; n=2; Nematostella ve... 159 2e-37
UniRef50_A7S448 Cluster: Predicted protein; n=2; Nematostella ve... 158 3e-37
UniRef50_Q2WF65 Cluster: Gaba/glycine receptor family (See gbr) ... 157 9e-37
UniRef50_A7S2G2 Cluster: Predicted protein; n=2; Nematostella ve... 157 9e-37
UniRef50_A7RZG9 Cluster: Predicted protein; n=3; Nematostella ve... 155 3e-36
UniRef50_Q9VDU9 Cluster: CG7411-PA; n=12; Endopterygota|Rep: CG7... 152 2e-35
UniRef50_Q17328 Cluster: Glutamate-gated chloride channel subuni... 151 3e-35
UniRef50_A7SH22 Cluster: Predicted protein; n=1; Nematostella ve... 149 2e-34
UniRef50_Q08861 Cluster: Gamma-aminobutyric acid-grated chloride... 147 7e-34
UniRef50_A7SAS4 Cluster: Predicted protein; n=2; Nematostella ve... 147 7e-34
UniRef50_A7SDF0 Cluster: Predicted protein; n=2; Nematostella ve... 146 1e-33
UniRef50_A7RTF6 Cluster: Predicted protein; n=2; Nematostella ve... 146 1e-33
UniRef50_Q9VGI0 Cluster: CG14723-PA, isoform A; n=12; Endopteryg... 146 2e-33
UniRef50_Q9GQ00 Cluster: Serotonin-gated chloride channel; n=4; ... 146 2e-33
UniRef50_A7RTF8 Cluster: Predicted protein; n=1; Nematostella ve... 146 2e-33
UniRef50_Q95QT7 Cluster: Glutamate-gated chloride channel protei... 141 4e-32
UniRef50_A7SCG0 Cluster: Predicted protein; n=1; Nematostella ve... 141 5e-32
UniRef50_Q9TVI7 Cluster: Putative uncharacterized protein; n=2; ... 140 6e-32
UniRef50_A7RT31 Cluster: Predicted protein; n=1; Nematostella ve... 140 6e-32
UniRef50_Q09453 Cluster: Glycine receptor subunit beta-type 4 pr... 140 9e-32
UniRef50_Q21005 Cluster: Putative uncharacterized protein acc-1;... 139 1e-31
UniRef50_A7LPG1 Cluster: Putative uncharacterized protein; n=3; ... 138 3e-31
UniRef50_UPI0000E48505 Cluster: PREDICTED: similar to inhibitory... 138 5e-31
UniRef50_Q20828 Cluster: Putative uncharacterized protein; n=2; ... 136 1e-30
UniRef50_Q9N517 Cluster: Putative uncharacterized protein; n=2; ... 136 2e-30
UniRef50_UPI0000ECC613 Cluster: Gamma-aminobutyric-acid receptor... 135 3e-30
UniRef50_Q9NA62 Cluster: Putative uncharacterized protein; n=1; ... 133 1e-29
UniRef50_Q22741 Cluster: Putative uncharacterized protein; n=2; ... 133 1e-29
UniRef50_Q10052 Cluster: Gaba/glycine receptor family (See gbr) ... 133 1e-29
UniRef50_UPI0000EB6CC4 Cluster: glycine receptor, beta b; n=1; D... 133 1e-29
UniRef50_Q621V5 Cluster: Putative uncharacterized protein CBG023... 132 2e-29
UniRef50_Q4RN70 Cluster: Chromosome undetermined SCAF15016, whol... 131 4e-29
UniRef50_Q9TZI5 Cluster: Expulsion defective (Defecation) protei... 131 5e-29
UniRef50_Q8SWZ1 Cluster: RH55021p; n=4; Diptera|Rep: RH55021p - ... 130 9e-29
UniRef50_O01792 Cluster: Putative uncharacterized protein; n=2; ... 129 2e-28
UniRef50_O17402 Cluster: Putative uncharacterized protein; n=2; ... 128 3e-28
UniRef50_Q7YTP9 Cluster: Putative uncharacterized protein; n=2; ... 128 4e-28
UniRef50_Q95Y52 Cluster: Putative uncharacterized protein; n=2; ... 127 6e-28
UniRef50_O17041 Cluster: Putative uncharacterized protein T15B7.... 127 9e-28
UniRef50_A7SQS7 Cluster: Predicted protein; n=1; Nematostella ve... 127 9e-28
UniRef50_Q8MM20 Cluster: Putative uncharacterized protein; n=3; ... 126 1e-27
UniRef50_Q0GQQ5 Cluster: Cys-loop ligand-gated ion channel subun... 126 1e-27
UniRef50_UPI00015B5BFB Cluster: PREDICTED: similar to cys-loop l... 124 8e-27
UniRef50_Q21420 Cluster: Putative uncharacterized protein; n=4; ... 123 1e-26
UniRef50_P41849 Cluster: Uncharacterized glycine receptor-like p... 123 1e-26
UniRef50_Q9U358 Cluster: Putative uncharacterized protein acc-4;... 119 2e-25
UniRef50_A7SAV3 Cluster: Predicted protein; n=1; Nematostella ve... 119 2e-25
UniRef50_Q4SC79 Cluster: Chromosome undetermined SCAF14659, whol... 117 9e-25
UniRef50_UPI0000F1E22C Cluster: PREDICTED: hypothetical protein;... 114 5e-24
UniRef50_A7SCG4 Cluster: Predicted protein; n=1; Nematostella ve... 114 5e-24
UniRef50_P91985 Cluster: Putative uncharacterized protein; n=1; ... 111 3e-23
UniRef50_Q4SJX0 Cluster: Chromosome 1 SCAF14573, whole genome sh... 109 2e-22
UniRef50_A7RF65 Cluster: Predicted protein; n=1; Nematostella ve... 106 1e-21
UniRef50_UPI0000D56CB7 Cluster: PREDICTED: similar to CG6927-PA;... 104 5e-21
UniRef50_UPI00015B49D8 Cluster: PREDICTED: similar to cys-loop l... 104 7e-21
UniRef50_UPI0000D56CB6 Cluster: PREDICTED: similar to CG6927-PA;... 103 1e-20
UniRef50_P90876 Cluster: Putative uncharacterized protein; n=2; ... 103 2e-20
UniRef50_Q9VUV2 Cluster: CG33989-PD, isoform D; n=2; Drosophila ... 99 1e-19
UniRef50_Q0GQQ4 Cluster: Cys-loop ligand-gated ion channel subun... 99 3e-19
UniRef50_Q9W4G1 Cluster: CG6927-PA; n=6; Diptera|Rep: CG6927-PA ... 97 1e-18
UniRef50_Q2PDY9 Cluster: CG33989-PF, isoform F; n=16; Endopteryg... 97 1e-18
UniRef50_Q9V9Y4 Cluster: CG11340-PA; n=2; Sophophora|Rep: CG1134... 97 1e-18
UniRef50_A7SDE9 Cluster: Predicted protein; n=1; Nematostella ve... 95 4e-18
UniRef50_UPI00015ADFAB Cluster: hypothetical protein NEMVEDRAFT_... 94 7e-18
UniRef50_Q61R47 Cluster: Putative uncharacterized protein CBG067... 89 4e-16
UniRef50_Q17KW1 Cluster: Glycine receptor beta, putative; n=1; A... 84 1e-14
UniRef50_Q6Q069 Cluster: Neuronal nicotinic acetylcholine Apisa7... 83 2e-14
UniRef50_UPI0000D55E50 Cluster: PREDICTED: similar to AcetylChol... 82 3e-14
UniRef50_Q2XWK6 Cluster: Nicotinic acetylcholine receptor subuni... 82 3e-14
UniRef50_A7NAE6 Cluster: Neurotransmitter-gated ion-channel liga... 80 1e-13
UniRef50_A7RS32 Cluster: Predicted protein; n=1; Nematostella ve... 80 2e-13
UniRef50_Q4RIA9 Cluster: Chromosome 8 SCAF15044, whole genome sh... 77 1e-12
UniRef50_A7S2P0 Cluster: Predicted protein; n=4; Nematostella ve... 76 2e-12
UniRef50_Q7T2R4 Cluster: Nicotinic acetylcholine receptor alpha ... 75 4e-12
UniRef50_Q5BW84 Cluster: SJCHGC08361 protein; n=1; Schistosoma j... 75 4e-12
UniRef50_A7SW63 Cluster: Predicted protein; n=3; Nematostella ve... 75 6e-12
UniRef50_Q6F6K3 Cluster: Acetylcholine receptor protein 17, isof... 73 1e-11
UniRef50_Q2XWK4 Cluster: Nicotinic acetylcholine receptor subuni... 73 1e-11
UniRef50_A7S3F7 Cluster: Predicted protein; n=1; Nematostella ve... 73 1e-11
UniRef50_P36544 Cluster: Neuronal acetylcholine receptor subunit... 73 1e-11
UniRef50_A7SI11 Cluster: Predicted protein; n=1; Nematostella ve... 72 4e-11
UniRef50_UPI0000E47621 Cluster: PREDICTED: similar to nicotinic ... 71 8e-11
UniRef50_Q4BXY7 Cluster: Neurotransmitter-gated ion-channel liga... 71 8e-11
UniRef50_A7UFK6 Cluster: Nicotinic acetylcholine receptor alpha ... 71 8e-11
UniRef50_UPI0000EBE733 Cluster: PREDICTED: similar to nicotinic ... 71 1e-10
UniRef50_A6FXF8 Cluster: Putative uncharacterized protein; n=1; ... 71 1e-10
UniRef50_P48182 Cluster: Acetylcholine receptor subunit beta-typ... 71 1e-10
UniRef50_Q9UGM1 Cluster: Neuronal acetylcholine receptor subunit... 71 1e-10
UniRef50_Q2XWK9 Cluster: Nicotinic acetylcholine receptor subuni... 70 1e-10
UniRef50_P17787 Cluster: Neuronal acetylcholine receptor subunit... 70 1e-10
UniRef50_UPI0000E49844 Cluster: PREDICTED: similar to nicotinic ... 70 2e-10
UniRef50_Q18556 Cluster: Putative uncharacterized protein acr-9;... 70 2e-10
UniRef50_A7RLP3 Cluster: Predicted protein; n=3; Nematostella ve... 70 2e-10
UniRef50_P54245 Cluster: Uncharacterized acetylcholine receptor-... 70 2e-10
UniRef50_Q9GP98 Cluster: Acetylcholine receptor protein 22; n=3;... 69 2e-10
UniRef50_Q7KT97 Cluster: CG32975-PB, isoform B; n=69; Eumetazoa|... 69 2e-10
UniRef50_A7RFJ5 Cluster: Predicted protein; n=2; Nematostella ve... 69 2e-10
UniRef50_A7RS33 Cluster: Predicted protein; n=1; Nematostella ve... 69 3e-10
UniRef50_Q4S864 Cluster: Chromosome 5 SCAF14709, whole genome sh... 69 4e-10
UniRef50_Q9N5U8 Cluster: Acetylcholine receptor protein 21; n=2;... 69 4e-10
UniRef50_Q0GQQ7 Cluster: PH-sensitive chloride channel variant 4... 69 4e-10
UniRef50_P11230 Cluster: Acetylcholine receptor subunit beta pre... 69 4e-10
UniRef50_Q23022 Cluster: Acetylcholine receptor subunit alpha-ty... 69 4e-10
UniRef50_Q9U298 Cluster: Neuronal acetylcholine receptor subunit... 67 1e-09
UniRef50_UPI000041A8E7 Cluster: PREDICTED: similar to Gamma-amin... 67 1e-09
UniRef50_A7S2N9 Cluster: Predicted protein; n=3; Nematostella ve... 67 1e-09
UniRef50_A7S2J7 Cluster: Predicted protein; n=1; Nematostella ve... 67 1e-09
UniRef50_Q60S81 Cluster: Neuronal acetylcholine receptor subunit... 66 2e-09
UniRef50_Q93329 Cluster: Putative uncharacterized protein lev-8;... 66 2e-09
UniRef50_Q8JFN7 Cluster: Neuronal acetylcholine receptor subunit... 66 3e-09
UniRef50_P46098 Cluster: 5-hydroxytryptamine receptor 3 precurso... 66 3e-09
UniRef50_UPI0000E48B7E Cluster: PREDICTED: similar to neuronal n... 65 4e-09
UniRef50_Q6QWI5 Cluster: Acetylcholine receptor 20 (63.9 kD) alt... 65 4e-09
UniRef50_A7RR86 Cluster: Predicted protein; n=1; Nematostella ve... 65 4e-09
UniRef50_UPI0000E49402 Cluster: PREDICTED: similar to alpha 10 s... 65 5e-09
UniRef50_A7RHV9 Cluster: Predicted protein; n=3; Nematostella ve... 65 5e-09
UniRef50_UPI0000586C99 Cluster: PREDICTED: similar to nicotinic ... 64 7e-09
UniRef50_Q70GM3 Cluster: Ligand-gated chloride channel subunit p... 64 7e-09
UniRef50_Q2XWK7 Cluster: Nicotinic acetylcholine receptor subuni... 64 7e-09
UniRef50_UPI0000E49401 Cluster: PREDICTED: similar to alpha 10 s... 64 9e-09
UniRef50_Q7ZTN5 Cluster: MGC52789 protein; n=1; Xenopus laevis|R... 64 9e-09
UniRef50_Q9NA46 Cluster: Putative uncharacterized protein acr-24... 64 9e-09
UniRef50_Q22224 Cluster: Putative uncharacterized protein acr-14... 64 9e-09
UniRef50_O16926 Cluster: Acetylcholine receptor protein 15; n=2;... 64 9e-09
UniRef50_P91766 Cluster: Acetylcholine receptor subunit alpha-li... 64 9e-09
UniRef50_UPI00015A3E3C Cluster: Neuronal acetylcholine receptor ... 64 1e-08
UniRef50_A7SNK1 Cluster: Predicted protein; n=2; Nematostella ve... 64 1e-08
UniRef50_A4TVG5 Cluster: Glycine receptor, alpha 4 subunit; n=1;... 63 2e-08
UniRef50_A7RNI2 Cluster: Predicted protein; n=3; Nematostella ve... 63 2e-08
UniRef50_Q27218 Cluster: Acetylcholine receptor subunit beta-typ... 63 2e-08
UniRef50_UPI0000E473D1 Cluster: PREDICTED: similar to neuronal a... 63 2e-08
UniRef50_Q4T6F3 Cluster: Chromosome 7 SCAF8790, whole genome sho... 63 2e-08
UniRef50_O61519 Cluster: Ligand-gated ion channel protein 6; n=4... 63 2e-08
UniRef50_UPI0000D55EDD Cluster: PREDICTED: similar to CG11822-PA... 62 3e-08
UniRef50_A7RK99 Cluster: Predicted protein; n=2; Nematostella ve... 62 3e-08
UniRef50_A0YQU9 Cluster: Putative uncharacterized protein; n=1; ... 62 4e-08
UniRef50_Q9VPQ8 Cluster: CG11822-PA, isoform A (Nicotinic acetyl... 62 5e-08
UniRef50_Q2XWL1 Cluster: Nicotinic acetylcholine receptor subuni... 62 5e-08
UniRef50_O61216 Cluster: Ligand-gated ion channel protein 30; n=... 62 5e-08
UniRef50_A7T134 Cluster: Predicted protein; n=1; Nematostella ve... 62 5e-08
UniRef50_UPI00015B4A35 Cluster: PREDICTED: similar to nicotinic ... 61 6e-08
UniRef50_Q4RRI3 Cluster: Chromosome 16 SCAF15002, whole genome s... 61 6e-08
UniRef50_Q66T35 Cluster: Nicotinic acetylcholine receptor subuni... 61 6e-08
UniRef50_A7RLM4 Cluster: Predicted protein; n=2; Nematostella ve... 61 6e-08
UniRef50_A7RJP2 Cluster: Predicted protein; n=1; Nematostella ve... 61 6e-08
UniRef50_A2TM50 Cluster: Nicotinic acetylcholine receptor alpha ... 61 6e-08
UniRef50_P43681 Cluster: Neuronal acetylcholine receptor subunit... 61 6e-08
UniRef50_P17644 Cluster: Acetylcholine receptor subunit alpha-li... 61 6e-08
UniRef50_UPI0000E48474 Cluster: PREDICTED: similar to nicotinic ... 61 8e-08
UniRef50_A7RNN1 Cluster: Predicted protein; n=2; Nematostella ve... 61 8e-08
UniRef50_A7RLM5 Cluster: Predicted protein; n=1; Nematostella ve... 61 8e-08
UniRef50_Q15822 Cluster: Neuronal acetylcholine receptor subunit... 61 8e-08
UniRef50_UPI0001560C7D Cluster: PREDICTED: similar to cholinergi... 60 1e-07
UniRef50_UPI0000E47D8F Cluster: PREDICTED: similar to nicotinic ... 60 1e-07
UniRef50_UPI0000E47C58 Cluster: PREDICTED: similar to nicotinic ... 60 1e-07
UniRef50_A2TM48 Cluster: Nicotinic acetylcholine receptor alpha ... 60 1e-07
UniRef50_Q7T2S3 Cluster: Nicotinic acetylcholine receptor alpha ... 60 1e-07
UniRef50_O62083 Cluster: Putative uncharacterized protein acr-19... 60 2e-07
UniRef50_O46132 Cluster: Nicotinic acetylcholine receptor, alpha... 60 2e-07
UniRef50_A7S9T6 Cluster: Predicted protein; n=2; Nematostella ve... 60 2e-07
UniRef50_Q4S3I6 Cluster: Chromosome 1 SCAF14749, whole genome sh... 59 3e-07
UniRef50_Q2XWL0 Cluster: Nicotinic acetylcholine receptor subuni... 59 3e-07
UniRef50_P25162 Cluster: Acetylcholine receptor subunit beta-lik... 59 3e-07
UniRef50_UPI000058727F Cluster: PREDICTED: similar to Chain B, R... 59 3e-07
UniRef50_Q7NDN8 Cluster: Glr4197 protein; n=1; Gloeobacter viola... 59 3e-07
UniRef50_P54244 Cluster: Acetylcholine receptor subunit alpha-ty... 59 3e-07
UniRef50_Q4S3I4 Cluster: Chromosome 1 SCAF14749, whole genome sh... 58 4e-07
UniRef50_Q67X94 Cluster: Putative uncharacterized protein lgc-2;... 58 4e-07
UniRef50_Q4RLA7 Cluster: Chromosome 21 SCAF15022, whole genome s... 58 6e-07
UniRef50_P54246 Cluster: Acetylcholine receptor subunit alpha-ty... 58 6e-07
UniRef50_UPI0000E464AB Cluster: PREDICTED: similar to nicotinic ... 58 8e-07
UniRef50_UPI0000E45D33 Cluster: PREDICTED: similar to nicotinic ... 58 8e-07
UniRef50_Q2XWK8 Cluster: Nicotinic acetylcholine receptor subuni... 58 8e-07
UniRef50_P91197 Cluster: Acetylcholine receptor protein 11; n=2;... 58 8e-07
UniRef50_O44452 Cluster: Putative uncharacterized protein; n=2; ... 58 8e-07
UniRef50_Q66T21 Cluster: Nicotinic acetylcholine receptor subuni... 57 1e-06
UniRef50_P30532 Cluster: Neuronal acetylcholine receptor subunit... 57 1e-06
UniRef50_Q2XWK3 Cluster: Nicotinic acetylcholine receptor subuni... 57 1e-06
UniRef50_A7S9T8 Cluster: Predicted protein; n=1; Nematostella ve... 57 1e-06
UniRef50_P04755 Cluster: Acetylcholine receptor subunit beta-lik... 57 1e-06
UniRef50_Q2XWL2 Cluster: Nicotinic acetylcholine receptor subuni... 56 2e-06
UniRef50_P48180 Cluster: Acetylcholine receptor subunit alpha-ty... 56 2e-06
UniRef50_UPI0000E49D12 Cluster: PREDICTED: similar to acetylchol... 56 2e-06
UniRef50_UPI00006A0062 Cluster: UPI00006A0062 related cluster; n... 56 2e-06
UniRef50_Q6TMY3 Cluster: Nicotinic acetylcholine receptor alpha ... 56 2e-06
UniRef50_O17848 Cluster: Putative uncharacterized protein acr-18... 56 2e-06
UniRef50_P45963 Cluster: Acetylcholine receptor subunit alpha-ty... 56 2e-06
UniRef50_P02708 Cluster: Acetylcholine receptor subunit alpha pr... 56 2e-06
UniRef50_Q4SXG5 Cluster: Chromosome undetermined SCAF12416, whol... 55 4e-06
UniRef50_Q9GUF0 Cluster: Ligand-gated ion channel protein 10; n=... 55 4e-06
UniRef50_A7RTX5 Cluster: Predicted protein; n=1; Nematostella ve... 55 4e-06
UniRef50_Q9GQU9 Cluster: Nicotinic acetylcholine receptor-like s... 55 5e-06
UniRef50_A5H038 Cluster: Nicotinic acetylcholine receptor subuni... 54 7e-06
UniRef50_O95264 Cluster: 5-hydroxytryptamine 3B receptor precurs... 54 1e-05
UniRef50_UPI0000E4930A Cluster: PREDICTED: similar to nicotinic ... 54 1e-05
UniRef50_UPI0000ECB6ED Cluster: Acetylcholine receptor subunit a... 54 1e-05
UniRef50_Q9XTE5 Cluster: Putative uncharacterized protein lgc-31... 54 1e-05
UniRef50_UPI0000E47C59 Cluster: PREDICTED: similar to alpha-9 ni... 53 2e-05
UniRef50_A7SRB3 Cluster: Predicted protein; n=3; Nematostella ve... 53 2e-05
UniRef50_Q4RZC6 Cluster: Chromosome 1 SCAF14944, whole genome sh... 53 2e-05
UniRef50_Q65XS8 Cluster: Acetylcholine receptor protein 25; n=2;... 53 2e-05
UniRef50_Q29ND1 Cluster: GA17977-PA; n=3; Schizophora|Rep: GA179... 53 2e-05
UniRef50_UPI0000E47720 Cluster: PREDICTED: similar to alpha-9 ni... 52 3e-05
UniRef50_A7SCG3 Cluster: Predicted protein; n=1; Nematostella ve... 52 3e-05
UniRef50_A6QL44 Cluster: Nicotinic acetylcholine receptor non-al... 52 3e-05
UniRef50_UPI00015B4DDF Cluster: PREDICTED: similar to neurotrans... 52 4e-05
UniRef50_Q4SRT2 Cluster: Chromosome undetermined SCAF14492, whol... 52 5e-05
UniRef50_UPI0000F1DA85 Cluster: PREDICTED: similar to MGC52789 p... 51 9e-05
UniRef50_O61884 Cluster: Acetylcholine receptor protein 23; n=2;... 51 9e-05
UniRef50_Q60KR8 Cluster: Putative uncharacterized protein CBG239... 50 1e-04
UniRef50_Q45U92 Cluster: GABA-A receptor; n=3; Caenorhabditis|Re... 50 1e-04
UniRef50_Q23355 Cluster: Putative uncharacterized protein acr-8;... 50 1e-04
UniRef50_UPI0000E4906F Cluster: PREDICTED: similar to nicotinic ... 50 2e-04
UniRef50_Q17BK9 Cluster: Nicotinic acetylcholine receptor, putat... 50 2e-04
UniRef50_A7S622 Cluster: Predicted protein; n=1; Nematostella ve... 50 2e-04
UniRef50_UPI0000F1DB4B Cluster: PREDICTED: hypothetical protein;... 49 3e-04
UniRef50_A7SAR5 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 49 3e-04
UniRef50_UPI0000E4906A Cluster: PREDICTED: similar to nicotinic ... 49 4e-04
UniRef50_Q4STL8 Cluster: Chromosome undetermined SCAF14147, whol... 48 5e-04
UniRef50_Q21645 Cluster: Acetylcholine receptor protein 10; n=2;... 48 5e-04
UniRef50_O76554 Cluster: Acetylcholine receptor subunit alpha-ty... 48 5e-04
UniRef50_UPI00006602DC Cluster: Homolog of Homo sapiens "5-hydro... 48 6e-04
UniRef50_Q4SXE7 Cluster: Chromosome undetermined SCAF12429, whol... 48 6e-04
UniRef50_Q9W288 Cluster: CG6698-PA; n=4; Sophophora|Rep: CG6698-... 48 6e-04
UniRef50_Q86YW4 Cluster: Ligand-gated ion channel subunit; n=10;... 48 6e-04
UniRef50_UPI0000584BCE Cluster: PREDICTED: hypothetical protein;... 48 8e-04
UniRef50_Q4S866 Cluster: Chromosome 5 SCAF14709, whole genome sh... 47 0.001
UniRef50_Q17BK7 Cluster: Nicotinic acetylcholine receptor, beta-... 47 0.001
UniRef50_UPI000058896A Cluster: PREDICTED: similar to cholinergi... 46 0.002
UniRef50_UPI0000ECD7CF Cluster: UPI0000ECD7CF related cluster; n... 46 0.002
UniRef50_Q6TMY0 Cluster: Nicotinic acetylcholine receptor non-al... 46 0.002
UniRef50_P07510 Cluster: Acetylcholine receptor subunit gamma pr... 46 0.002
UniRef50_A7RUG1 Cluster: Predicted protein; n=2; Nematostella ve... 46 0.003
UniRef50_Q04844 Cluster: Acetylcholine receptor subunit epsilon ... 46 0.003
UniRef50_UPI0000E4A8FD Cluster: PREDICTED: similar to Cholinergi... 45 0.004
UniRef50_Q9N4M3 Cluster: Acetylcholine receptor protein 6; n=1; ... 45 0.004
UniRef50_UPI00006603C6 Cluster: Homolog of Homo sapiens "5-hydro... 45 0.006
UniRef50_A7RFJ2 Cluster: Predicted protein; n=1; Nematostella ve... 45 0.006
UniRef50_UPI0000E477D1 Cluster: PREDICTED: similar to nicotinic ... 44 0.008
UniRef50_UPI0000E47329 Cluster: PREDICTED: similar to novel chol... 44 0.008
UniRef50_UPI0000660F16 Cluster: Homolog of Homo sapiens "Splice ... 44 0.008
UniRef50_Q6U4B6 Cluster: Nicotinic acetylcholine receptor alpha ... 44 0.008
UniRef50_Q07001 Cluster: Acetylcholine receptor subunit delta pr... 44 0.008
UniRef50_UPI0000E49087 Cluster: PREDICTED: similar to Glra4a pro... 44 0.010
UniRef50_UPI0000F2C37E Cluster: PREDICTED: similar to CHRNG prot... 43 0.018
UniRef50_UPI0000E46D49 Cluster: PREDICTED: similar to nicotinic ... 43 0.018
UniRef50_O18228 Cluster: Putative uncharacterized protein lgc-7;... 43 0.018
UniRef50_Q6U4B5 Cluster: Nicotinic acetylcholine receptor beta 1... 43 0.024
UniRef50_Q61KY4 Cluster: Putative uncharacterized protein CBG091... 43 0.024
UniRef50_A7S2G5 Cluster: Predicted protein; n=1; Nematostella ve... 43 0.024
UniRef50_UPI000069F132 Cluster: 5-hydroxytryptamine receptor 3 s... 42 0.031
UniRef50_Q22085 Cluster: Putative uncharacterized protein lgc-17... 42 0.031
UniRef50_Q19351 Cluster: Ligand-gated ion channel protein 3; n=3... 42 0.031
UniRef50_UPI0000E4929C Cluster: PREDICTED: similar to nicotinic ... 42 0.041
UniRef50_Q4RU50 Cluster: Chromosome 1 SCAF14995, whole genome sh... 42 0.041
UniRef50_Q2XWK5 Cluster: Nicotinic acetylcholine receptor subuni... 42 0.041
UniRef50_A0EIZ7 Cluster: Nicotinic acetylcholine receptor alpha9... 42 0.041
UniRef50_Q7Z6B2 Cluster: 5-hydroxytryptamine serotonin receptor ... 42 0.041
UniRef50_Q5BZP4 Cluster: SJCHGC07923 protein; n=1; Schistosoma j... 42 0.055
UniRef50_UPI000065F0EC Cluster: Homolog of Homo sapiens "5-hydro... 41 0.072
UniRef50_A7SXU2 Cluster: Predicted protein; n=1; Nematostella ve... 41 0.072
UniRef50_Q9XTY8 Cluster: Putative uncharacterized protein lgc-25... 41 0.096
UniRef50_Q231C1 Cluster: Putative uncharacterized protein; n=1; ... 40 0.13
UniRef50_UPI0000EBED4A Cluster: PREDICTED: similar to gamma-amin... 40 0.17
UniRef50_A6FMG2 Cluster: Putative uncharacterized protein; n=1; ... 40 0.17
UniRef50_Q6PNB8 Cluster: GABA-A gamma 3 subunit; n=6; Tetrapoda|... 40 0.17
UniRef50_A7SQS5 Cluster: Predicted protein; n=1; Nematostella ve... 40 0.17
UniRef50_Q8TA51 Cluster: Putative uncharacterized protein; n=3; ... 40 0.22
UniRef50_UPI00015B60A2 Cluster: PREDICTED: similar to nicotinic ... 39 0.29
UniRef50_UPI0000E4902F Cluster: PREDICTED: similar to Acetylchol... 39 0.29
UniRef50_A4CWI3 Cluster: Putative uncharacterized protein; n=1; ... 39 0.39
UniRef50_O16379 Cluster: Putative uncharacterized protein; n=2; ... 39 0.39
UniRef50_UPI0000E46711 Cluster: PREDICTED: similar to Neuronal a... 38 0.51
UniRef50_Q4RNA9 Cluster: Chromosome 1 SCAF15015, whole genome sh... 38 0.51
UniRef50_Q7RAS7 Cluster: Putative uncharacterized protein PY0642... 38 0.51
UniRef50_UPI0000D56B27 Cluster: PREDICTED: similar to CG10538-PA... 38 0.68
UniRef50_UPI000069FF34 Cluster: UPI000069FF34 related cluster; n... 38 0.89
UniRef50_UPI0000D56893 Cluster: PREDICTED: similar to CG6698-PA;... 37 1.2
UniRef50_Q9WV58 Cluster: Gamma-aminobutyric acid A receptor gamm... 37 1.2
UniRef50_Q8BQW9 Cluster: Adult male corpora quadrigemina cDNA, R... 37 1.2
UniRef50_A7S8Q4 Cluster: Predicted protein; n=3; Nematostella ve... 37 1.2
UniRef50_A7I712 Cluster: Putative uncharacterized protein precur... 37 1.2
UniRef50_UPI0000587F11 Cluster: PREDICTED: similar to alpha 10 s... 37 1.6
UniRef50_UPI00006A0317 Cluster: 5-hydroxytryptamine 3 receptor p... 37 1.6
UniRef50_Q1ZEF5 Cluster: NADH-ubiquinone oxidoreductase; n=1; Ps... 37 1.6
UniRef50_Q8I528 Cluster: DNA topoisomerase 2; n=1; Plasmodium fa... 37 1.6
UniRef50_Q624E0 Cluster: Putative uncharacterized protein CBG016... 37 1.6
UniRef50_A6XBS1 Cluster: Amorphous calcium carbonate binding pro... 37 1.6
UniRef50_Q6U4B7 Cluster: Nicotinic acetylcholine receptor alpha ... 36 2.1
UniRef50_A0BMM2 Cluster: Chromosome undetermined scaffold_116, w... 36 2.1
UniRef50_Q8IHP8 Cluster: Putative uncharacterized protein; n=2; ... 36 2.7
UniRef50_UPI0000E4771F Cluster: PREDICTED: hypothetical protein;... 36 3.6
UniRef50_Q4W520 Cluster: Putative uncharacterized protein; n=1; ... 36 3.6
UniRef50_Q8IE48 Cluster: Putative uncharacterized protein PF13_0... 35 4.8
UniRef50_Q54DT1 Cluster: ABC transporter A family protein; n=5; ... 35 4.8
UniRef50_Q4N2C5 Cluster: Putative uncharacterized protein; n=1; ... 35 4.8
UniRef50_Q8TLI2 Cluster: Predicted protein; n=2; Methanosarcina|... 35 4.8
UniRef50_UPI00015B5C6B Cluster: PREDICTED: similar to nicotinic ... 35 6.3
UniRef50_Q8IL74 Cluster: Putative uncharacterized protein; n=1; ... 35 6.3
UniRef50_Q54Z33 Cluster: Putative uncharacterized protein; n=1; ... 35 6.3
UniRef50_UPI000051DDF1 Cluster: ACETYLCHOLINE-BINDING PROTEIN; n... 34 8.3
UniRef50_UPI0000F1E62D Cluster: PREDICTED: hypothetical protein;... 34 8.3
UniRef50_Q8G4F4 Cluster: ATP-dependent helicase II; n=2; Bifidob... 34 8.3
UniRef50_A0QZR2 Cluster: Acyl-CoA dehydrogenase; n=1; Mycobacter... 34 8.3
UniRef50_Q9FGV5 Cluster: Genomic DNA, chromosome 5, TAC clone:K1... 34 8.3
UniRef50_Q7M3M7 Cluster: Gamma-aminobutyric acid A receptor; n=1... 34 8.3
UniRef50_Q5DAX0 Cluster: SJCHGC06429 protein; n=1; Schistosoma j... 34 8.3
>UniRef50_Q4V4V5 Cluster: IP12579p; n=6; Endopterygota|Rep: IP12579p
- Drosophila melanogaster (Fruit fly)
Length = 612
Score = 442 bits (1089), Expect = e-122
Identities = 202/271 (74%), Positives = 233/271 (85%), Gaps = 2/271 (0%)
Query: 117 NYANSSFEQTDVFTWKQNKR-SINDAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQT 175
N N S+ +++ ++ +R + D +S+NI+ +LENLLK YE SQLPTHG+G PTVVQT
Sbjct: 78 NATNLSYSSSEISNQRRVRRKAAADMLSRNISMILENLLKRYEQSQLPTHGQGVPTVVQT 137
Query: 176 NILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYN 235
NILIRSMGPVSELDMDYSMDCYFRQYWRD RLSF GPI+SLSLSIKML++IWRPDTYFYN
Sbjct: 138 NILIRSMGPVSELDMDYSMDCYFRQYWRDKRLSFKGPIKSLSLSIKMLDKIWRPDTYFYN 197
Query: 236 GKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYS 295
GKHS +H ITVPNKLLR+ Q+G ILYSMRLTIKA CPMEL+NFPMDRQSCPL++GSY Y
Sbjct: 198 GKHSQIHMITVPNKLLRLDQNGGILYSMRLTIKATCPMELQNFPMDRQSCPLVIGSYGYI 257
Query: 296 NQQLVYQWQN-SQSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGY 354
NQQL+Y+W+N +V+FVPGMTL+QFDLIS +RNFT RREGDFSVL V+FNLKRHTGY
Sbjct: 258 NQQLIYEWKNQDDAVSFVPGMTLNQFDLISMMHRNFTTVRREGDFSVLHVAFNLKRHTGY 317
Query: 355 FLIQVYVPCILIVVLSWVSFWIHREVGSGEI 385
FLIQVYVPCILIVVLSWVSFWIHRE S +
Sbjct: 318 FLIQVYVPCILIVVLSWVSFWIHREATSDRV 348
Score = 85.0 bits (201), Expect = 4e-15
Identities = 44/91 (48%), Positives = 56/91 (61%), Gaps = 9/91 (9%)
Query: 450 TMERTTQTET-RVPRWRQLLYCLAGDDRYRRQRQREA--------GSRGHINSVSHIDRA 500
TMERTTQTE V R Q+ CL D+ +R+QR+R A G+ ++NSVS IDR
Sbjct: 519 TMERTTQTEPPAVSRLHQMWMCLKSDNSFRKQRERNAAAQKSEQGGANCYVNSVSLIDRV 578
Query: 501 ARVLFPASFALLNLFYWMIYAFSSDDFAWSD 531
AR+ FP SFA LNL YW Y +F+WS+
Sbjct: 579 ARIAFPMSFAFLNLLYWWAYGMYKKEFSWSN 609
>UniRef50_Q0GQQ6 Cluster: Cys-loop ligand-gated ion channel subunit;
n=3; Endopterygota|Rep: Cys-loop ligand-gated ion
channel subunit - Apis mellifera (Honeybee)
Length = 510
Score = 429 bits (1057), Expect = e-119
Identities = 202/250 (80%), Positives = 218/250 (87%), Gaps = 1/250 (0%)
Query: 137 SINDAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDC 196
++ND VS+NIT VLENLL NYEN+QLPTHGKG PTVV+TNILIRSMGPVSELDMDYSMDC
Sbjct: 28 TVNDIVSRNITMVLENLLMNYENNQLPTHGKGTPTVVKTNILIRSMGPVSELDMDYSMDC 87
Query: 197 YFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQH 256
YFRQ WRD+RLSFLGPI+SLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQ
Sbjct: 88 YFRQSWRDSRLSFLGPIKSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQD 147
Query: 257 GDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFV-PGM 315
GDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGS Q + + ++ PGM
Sbjct: 148 GDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSCKCIYVQSINLCMAGRLFGYLCPGM 207
Query: 316 TLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFW 375
LSQFDL+ PYRN TF RREG+FSVLQVSFNL+RHTGYFLIQVYVPC+LIVVLSWVSFW
Sbjct: 208 ALSQFDLMGSPYRNLTFVRREGEFSVLQVSFNLQRHTGYFLIQVYVPCVLIVVLSWVSFW 267
Query: 376 IHREVGSGEI 385
IHRE S +
Sbjct: 268 IHREATSDRV 277
Score = 123 bits (296), Expect = 1e-26
Identities = 74/202 (36%), Positives = 105/202 (51%), Gaps = 18/202 (8%)
Query: 354 YFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVIDDSEWEELIEEVGGDXXXXXXXXX-- 411
+FL+ + CI +L + +VGSGEI +++ EWE E D
Sbjct: 309 WFLLMSFGYCIA-TLLEFAGVHYFTKVGSGEIPLEEEEWENENESDYQDAFCNIVSCSPQ 367
Query: 412 ----XXXXXXXXXTNNLSMPSQSSNPTTS--DNLETEQPVAVRLTMERTTQTETRVPRWR 465
++L N + S T + TMER TQTE +P+WR
Sbjct: 368 TVHPETIIDVSRRRSSLICDVYGVNESVSYERGSMTVSVTSKPSTMERQTQTEVWIPKWR 427
Query: 466 QLLYCLAGDDRYRRQRQREAGS----RG-----HINSVSHIDRAARVLFPASFALLNLFY 516
Q LYCLAGD+ +R++RQREA RG HINSVS+ID+ AR++FPASF LLN+ Y
Sbjct: 428 QFLYCLAGDESFRKRRQREAAGNCRKRGEKIARHINSVSYIDKVARIVFPASFGLLNICY 487
Query: 517 WMIYAFSSDDFAWSDNPINTLS 538
W+IY ++F W D+P+ ++S
Sbjct: 488 WVIYVTYQEEFKWQDSPLGSIS 509
>UniRef50_UPI00015B5C4C Cluster: PREDICTED: similar to GABA-gated
ion channel; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to GABA-gated ion channel - Nasonia vitripennis
Length = 442
Score = 302 bits (741), Expect = 2e-80
Identities = 137/241 (56%), Positives = 176/241 (73%), Gaps = 1/241 (0%)
Query: 145 NITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 204
NI+ +L+NLL+ Y+NS P G G P VV+ +I++RSMGP+SE+DM YSMDCYFRQ W D
Sbjct: 49 NISELLDNLLRGYDNSVRPNFG-GPPAVVEVDIMVRSMGPISEVDMTYSMDCYFRQSWVD 107
Query: 205 TRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
RL+F +L+LSI ML RIW+PDTYFYNGK SY+HTIT PNK +R+ Q G +LYS R
Sbjct: 108 RRLAFQSGKETLALSISMLARIWKPDTYFYNGKQSYLHTITSPNKFVRLYQDGRVLYSSR 167
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLIS 324
LTIKA CPM L +FPMD Q CPL GSY Y+ + ++Y+W +++ V M LSQFDL+
Sbjct: 168 LTIKAACPMNLEDFPMDTQRCPLKFGSYGYTTRDVIYKWNSARQVAIAHDMKLSQFDLVG 227
Query: 325 FPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGE 384
P N T + +S+L VSF+LKRH G FLIQVY PC+L+VVLSWVSFW++RE +
Sbjct: 228 NPTANATDSTLSQKYSMLLVSFHLKRHMGNFLIQVYGPCVLLVVLSWVSFWLNREATADR 287
Query: 385 I 385
+
Sbjct: 288 V 288
Score = 44.4 bits (100), Expect = 0.008
Identities = 18/29 (62%), Positives = 22/29 (75%)
Query: 492 NSVSHIDRAARVLFPASFALLNLFYWMIY 520
NSVS IDRA+R++FP F +NLFYW Y
Sbjct: 404 NSVSKIDRASRLVFPLFFLAINLFYWFAY 432
>UniRef50_Q0GQR6 Cluster: GABA-gated ion channel; n=2; Apis
mellifera|Rep: GABA-gated ion channel - Apis mellifera
(Honeybee)
Length = 463
Score = 301 bits (740), Expect = 2e-80
Identities = 136/243 (55%), Positives = 179/243 (73%), Gaps = 3/243 (1%)
Query: 145 NITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 204
NI+ +L+NLL+ Y+NS P G G P V+ +I++RSMGP+SE+DM YSMDCYFRQ W D
Sbjct: 5 NISELLDNLLRGYDNSVRPDFG-GPPATVEVDIMVRSMGPISEVDMTYSMDCYFRQSWVD 63
Query: 205 TRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
RL+F G +L+LSI ML RIW+PDTYFYNGKHSY+HTIT PNK +R+ Q G +LYS R
Sbjct: 64 RRLAFQGGKETLALSISMLARIWKPDTYFYNGKHSYLHTITSPNKFVRLYQDGRVLYSSR 123
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLIS 324
LTIKA CPM L NFPMD Q CPL GS+ Y+ + ++Y+W +++ V M LSQFDL++
Sbjct: 124 LTIKAGCPMNLENFPMDTQRCPLQFGSFGYTKRDVIYKWNSARQVAIAEDMKLSQFDLVA 183
Query: 325 FPYRNF--TFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGS 382
P N+ + T ++S+L V F+L+RH G FLIQVY PC+L+VVLSWVSFW++RE +
Sbjct: 184 NPTANYSASTTLSHAEYSMLLVYFHLQRHMGNFLIQVYGPCVLLVVLSWVSFWLNREATA 243
Query: 383 GEI 385
+
Sbjct: 244 DRV 246
Score = 46.4 bits (105), Expect = 0.002
Identities = 34/117 (29%), Positives = 50/117 (42%), Gaps = 18/117 (15%)
Query: 427 PSQSSNPTTSDNLETEQPVAVRLTMERTTQTE----TRVPR---------WRQLLYCLAG 473
P SN T+ NL T + + TM E + +P W+ +
Sbjct: 335 PITQSNKRTAGNLATREHPSRNFTMSEDGMIEVIPLSAIPEPSKNPAMGHWQMSCVACSP 394
Query: 474 DDRYRRQRQREAGSRGH-----INSVSHIDRAARVLFPASFALLNLFYWMIYAFSSD 525
R ++E+G R NSVS IDRA+R++FP F +N+FYW Y S+
Sbjct: 395 PPRQTPPSRKESGRRRRRRTPRYNSVSKIDRASRIVFPLFFLAINVFYWFAYLSRSE 451
>UniRef50_Q8WSF7 Cluster: GABA A receptor alpha subunit; n=1;
Aplysia californica|Rep: GABA A receptor alpha subunit -
Aplysia californica (California sea hare)
Length = 448
Score = 268 bits (657), Expect = 3e-70
Identities = 124/245 (50%), Positives = 168/245 (68%), Gaps = 3/245 (1%)
Query: 145 NITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 204
NI+ VL++LL+ Y+ P G G V +I +RSMGP+SEL+M Y++DCYFRQ W D
Sbjct: 33 NISQVLDSLLEGYDKRLRPGFG-GEALTVNADISLRSMGPISELNMIYTLDCYFRQRWMD 91
Query: 205 TRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
RL+ + +L+L IK+LERIW PDT FYNG+ SY+H IT N+ LRI+ +G +L+S R
Sbjct: 92 HRLAMNVSLENLTLGIKILERIWHPDTVFYNGQKSYLHAITSHNRFLRIAANGTVLFSQR 151
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQN--SQSVNFVPGMTLSQFDL 322
LTI+A C M NFPMD Q CPL++GS+AYS ++Y+W+ S+ P + LSQFDL
Sbjct: 152 LTIQATCRMHPENFPMDIQHCPLLIGSFAYSTDDVIYKWRYGLQGSIELAPDLRLSQFDL 211
Query: 323 ISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGS 382
+ +P N+T + SVL V+F L RHTGYFLI +Y+PC L+VVLSW SFWI+RE +
Sbjct: 212 VGYPLTNYTGLVKGAVHSVLCVTFQLSRHTGYFLINLYLPCCLLVVLSWASFWINREATA 271
Query: 383 GEIVI 387
I +
Sbjct: 272 DRIAL 276
Score = 42.7 bits (96), Expect = 0.024
Identities = 25/56 (44%), Positives = 33/56 (58%), Gaps = 4/56 (7%)
Query: 466 QLLYCLAGDDRYRRQRQREAGSRGHI-NSVSHIDRAARVLFPASFALLNLFYWMIY 520
+L +CL R + R R G NSVS +DRAARVLFP +F +LN+ Y + Y
Sbjct: 388 KLCHCLT---RTKDGRGRMKGKLSMFSNSVSQVDRAARVLFPLTFTVLNVIYCVSY 440
>UniRef50_Q6BET0 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 536
Score = 243 bits (595), Expect = 8e-63
Identities = 122/286 (42%), Positives = 173/286 (60%), Gaps = 10/286 (3%)
Query: 111 NEIMFSNYANSSFEQTDVFTWKQNKRSIND-AVSKNITSVLENLLKNYENSQLPTHGKGY 169
NE+ F+ N F F K+ + V++N+T +L N+LKNY+ P G
Sbjct: 27 NELKFT-IENVKFRSPGSFRIKRTVHPKREKGVAQNVTHLLNNVLKNYDQHFRPGFNSGK 85
Query: 170 PTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGP---IRSLSLSIKMLERI 226
PT V ++ IR+MGPVS+L YS +CYFRQ W D RL F R LSLS+ ML++I
Sbjct: 86 PTKVYIDLFIRTMGPVSDLFNTYSFNCYFRQKWTDDRLHFNNSGIGFRQLSLSMAMLDKI 145
Query: 227 WRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCP 286
W+PDTYF+NG SYVH IT N+L+R+ G ILYS R+T+KAKC M++ +P+D+Q+C
Sbjct: 146 WKPDTYFWNGAGSYVHGITTSNRLVRLEPDGTILYSSRITVKAKCQMDMSRYPLDKQACR 205
Query: 287 LILGSYAYSNQQLVYQWQ-----NSQSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFSV 341
L++GSYAYS+ ++ Y+W+ N +++ L QF L F R+ ++S
Sbjct: 206 LVIGSYAYSSDEVQYKWRIMGDDNGVKIDYESIADLPQFSLSGFKVYKPANITRDKEYSA 265
Query: 342 LQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVI 387
L+V F RH GYFL+ YVPC L+V+L WV+F+ RE + I I
Sbjct: 266 LEVRFYFDRHFGYFLMNFYVPCALVVLLCWVAFFTKREATAERIGI 311
>UniRef50_P31644 Cluster: Gamma-aminobutyric acid receptor subunit
alpha-5 precursor (GABA(A) receptor subunit alpha-5);
n=86; Euteleostomi|Rep: Gamma-aminobutyric acid receptor
subunit alpha-5 precursor (GABA(A) receptor subunit
alpha-5) - Homo sapiens (Human)
Length = 462
Score = 241 bits (591), Expect = 2e-62
Identities = 112/249 (44%), Positives = 163/249 (65%), Gaps = 7/249 (2%)
Query: 137 SINDAVSKNIT---SVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYS 193
S+ D + NIT +L+ LL Y+N P G+ T V+T+I + S GPVS+ +M+Y+
Sbjct: 37 SVKDETNDNITIFTRILDGLLDGYDNRLRPGLGERI-TQVRTDIYVTSFGPVSDTEMEYT 95
Query: 194 MDCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRI 253
+D +FRQ W+D RL F GP++ L L+ + +IW PDT+F+NGK S H +T PNKLLR+
Sbjct: 96 IDVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRL 155
Query: 254 SQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFV- 312
G +LY+MRLTI A+CPM+L +FPMD +CPL GSYAY N ++VY W N + + V
Sbjct: 156 EDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVV 215
Query: 313 --PGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLS 370
G L+Q+ L+ + G+++++ F+LKR GYF+IQ Y+PCI+ V+LS
Sbjct: 216 AEDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILS 275
Query: 371 WVSFWIHRE 379
VSFW++RE
Sbjct: 276 QVSFWLNRE 284
Score = 39.5 bits (88), Expect = 0.22
Identities = 15/39 (38%), Positives = 24/39 (61%)
Query: 482 QREAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
++ + S+ NS+S ID+ +R++FP F NL YW Y
Sbjct: 410 EKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATY 448
>UniRef50_P48169 Cluster: Gamma-aminobutyric acid receptor subunit
alpha-4 precursor (GABA(A) receptor subunit alpha-4);
n=26; Euteleostomi|Rep: Gamma-aminobutyric acid receptor
subunit alpha-4 precursor (GABA(A) receptor subunit
alpha-4) - Homo sapiens (Human)
Length = 554
Score = 238 bits (582), Expect = 3e-61
Identities = 113/240 (47%), Positives = 159/240 (66%), Gaps = 4/240 (1%)
Query: 143 SKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYW 202
++N T +L++LL Y+N P G G T V+T+I + S GPVS+++M+Y+MD +FRQ W
Sbjct: 45 TENFTRILDSLLDGYDNRLRPGFG-GPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTW 103
Query: 203 RDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYS 262
D RL + GPI L L+ M+ ++W PDT+F NGK S H +T PNKL RI ++G ILY+
Sbjct: 104 IDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYT 163
Query: 263 MRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNF-VP--GMTLSQ 319
MRLTI A+CPM L +FPMD +CPL GSYAY +++Y W + VP +L Q
Sbjct: 164 MRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTKGPEKSVEVPKESSSLVQ 223
Query: 320 FDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
+DLI + T G++ V+ V F+L+R GYF+IQ Y+PCI+ V+LS VSFWI++E
Sbjct: 224 YDLIGQTVSSETIKSITGEYIVMTVYFHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKE 283
Score = 38.7 bits (86), Expect = 0.39
Identities = 16/41 (39%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
Query: 492 NSVSHIDRAARVLFPASFALLNLFYWMIYAFSSDDFAWSDN 532
+ S ID+ AR+LFP +F N+ YW++Y S D S++
Sbjct: 513 SGTSKIDKYARILFPVTFGAFNMVYWVVY-LSKDTMEKSES 552
>UniRef50_P34903 Cluster: Gamma-aminobutyric acid receptor subunit
alpha-3 precursor (GABA(A) receptor subunit alpha-3);
n=94; Euteleostomi|Rep: Gamma-aminobutyric acid receptor
subunit alpha-3 precursor (GABA(A) receptor subunit
alpha-3) - Homo sapiens (Human)
Length = 492
Score = 234 bits (572), Expect = 5e-60
Identities = 110/236 (46%), Positives = 154/236 (65%), Gaps = 4/236 (1%)
Query: 147 TSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTR 206
T +L+ LL Y+N P G T V+T+I + S GPVS+ DM+Y++D +FRQ W D R
Sbjct: 68 TRILDRLLDGYDNRLRPGLGDAV-TEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDER 126
Query: 207 LSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLT 266
L F GP++ L L+ + +IW PDT+F+NGK S H +T PNKLLR+ +G +LY+MRLT
Sbjct: 127 LKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLT 186
Query: 267 IKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQ--NSQSVNFV-PGMTLSQFDLI 323
I A+CPM L +FPMD +CPL GSYAY+ ++VY W ++SV G L+Q+DL+
Sbjct: 187 IHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLL 246
Query: 324 SFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
G++ V+ F+LKR GYF+IQ Y+PCI+ V+LS VSFW++RE
Sbjct: 247 GHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 302
Score = 41.5 bits (93), Expect = 0.055
Identities = 15/29 (51%), Positives = 21/29 (72%)
Query: 492 NSVSHIDRAARVLFPASFALLNLFYWMIY 520
NSVS +D+ +R++FP FA+ NL YW Y
Sbjct: 450 NSVSKVDKISRIIFPVLFAIFNLVYWATY 478
>UniRef50_Q24352 Cluster: Gamma-aminobutyric acid receptor
alpha-like precursor (GABA(A) receptor alpha-like and
glycine receptor-like subunit of Drosophila); n=3;
Diptera|Rep: Gamma-aminobutyric acid receptor alpha-like
precursor (GABA(A) receptor alpha-like and glycine
receptor-like subunit of Drosophila) - Drosophila
melanogaster (Fruit fly)
Length = 686
Score = 231 bits (564), Expect = 5e-59
Identities = 105/188 (55%), Positives = 134/188 (71%), Gaps = 2/188 (1%)
Query: 145 NITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 204
NI+ +L+NLL+ Y+NS P G G P ++ +I++RSMGP+SE+DM YSMDCYFRQ W D
Sbjct: 108 NISELLDNLLRGYDNSIRPDFG-GPPATIEVDIMVRSMGPISEVDMTYSMDCYFRQSWVD 166
Query: 205 TRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
RL+F G +L+LS+ ML RIW+PDTYFYNGK SY+HTIT PNK +RI Q+G +LYS R
Sbjct: 167 KRLAFEGAQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVLYSSR 226
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQ-SVNFVPGMTLSQFDLI 323
LTIKA CPM L +FPMD Q CPL GS+ Y+ ++Y+W + V M LSQFDL+
Sbjct: 227 LTIKAGCPMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMKLSQFDLV 286
Query: 324 SFPYRNFT 331
P N T
Sbjct: 287 DCPAGNLT 294
Score = 70.5 bits (165), Expect = 1e-10
Identities = 29/53 (54%), Positives = 40/53 (75%)
Query: 333 TRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEI 385
T ++S+L V+F+L+RH G FLIQVY PC L+VVLSWVSFW++RE + +
Sbjct: 372 TNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREATADRV 424
Score = 47.6 bits (108), Expect = 8e-04
Identities = 23/48 (47%), Positives = 31/48 (64%), Gaps = 4/48 (8%)
Query: 477 YRRQRQREAGSRG----HINSVSHIDRAARVLFPASFALLNLFYWMIY 520
Y R+ + EA +G NSVS IDRA+R++FP F L+N+FYW Y
Sbjct: 623 YYRREEMEARRKGKRTPQYNSVSKIDRASRIVFPLLFILINVFYWYGY 670
>UniRef50_Q25035 Cluster: GABA A/glycine receptor subunit; n=3;
Rhabditida|Rep: GABA A/glycine receptor subunit -
Haemonchus contortus (Barber pole worm)
Length = 472
Score = 227 bits (555), Expect = 6e-58
Identities = 113/262 (43%), Positives = 166/262 (63%), Gaps = 8/262 (3%)
Query: 133 QNKRSI-NDAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMD 191
+N+RS N + T +L +L N + PT+ P V+ +I +RSMGP+SE DM+
Sbjct: 22 RNERSTYNTTLISYTTKLLNTILLNQDKKFRPTNPDSSPLNVEIDISVRSMGPISEQDME 81
Query: 192 YSMDCYFRQYWRDTRLSF--LGPIRS-LSLSIKMLERIWRPDTYFYNGKHSYVHTITVPN 248
+S+DCYFRQ W D RL+F + P + + L+ KML+ IW PDTY NG+ SY+HT+TVPN
Sbjct: 82 FSLDCYFRQKWLDRRLAFTPINPDKPVMPLASKMLKDIWVPDTYIRNGRKSYLHTLTVPN 141
Query: 249 KLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQS 308
L R+ G + S RLTIK KC M L+ FPMD Q+CP+ +GS Y + +VY W++ +
Sbjct: 142 ILFRVRSDGQVHVSQRLTIKTKCLMFLKKFPMDVQACPIEIGSLGYFSNDVVYYWKDVE- 200
Query: 309 VNFVPGMTLSQFDLISF--PYRNFTFTRREG-DFSVLQVSFNLKRHTGYFLIQVYVPCIL 365
++ G LSQ+ ++ NF+ R G + SVL+V F L+R GY+++Q+Y PC L
Sbjct: 201 LDAKMGNMLSQYKILGLFKSEHNFSDHREIGRNISVLKVYFKLQRQQGYYVLQIYTPCTL 260
Query: 366 IVVLSWVSFWIHREVGSGEIVI 387
+VV+SWVSFWI++E + +
Sbjct: 261 LVVMSWVSFWINKEASPARVAL 282
>UniRef50_UPI0000E20C28 Cluster: PREDICTED: gamma-aminobutyric acid
A receptor, alpha 6 isoform 1; n=1; Pan troglodytes|Rep:
PREDICTED: gamma-aminobutyric acid A receptor, alpha 6
isoform 1 - Pan troglodytes
Length = 478
Score = 225 bits (550), Expect = 2e-57
Identities = 117/265 (44%), Positives = 161/265 (60%), Gaps = 29/265 (10%)
Query: 143 SKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYW 202
S+N++ +L+NLL+ Y+N P G G T V+T+I + S GPVS+++M+Y+MD +FRQ W
Sbjct: 29 SENVSRILDNLLEGYDNRLRPGFG-GAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTW 87
Query: 203 RDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYS 262
D RL F GP LSL+ M+ +IW PDT+F NGK S H +T PNKL RI Q+G ILY+
Sbjct: 88 TDERLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYT 147
Query: 263 MRLTIKAKCPMELRNFPMDRQSCPLILGSY-------------------------AYSNQ 297
MRLTI A CPM L NFPMD +CPL GSY AY
Sbjct: 148 MRLTINADCPMRLVNFPMDGHACPLKFGSYNVHFEGKKDNSSNSLLYLICFKYLDAYPKS 207
Query: 298 QLVYQWQNSQSVNF-VP--GMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGY 354
+++Y W+ + VP +L Q+DLI + T G++ ++ V F+L+R GY
Sbjct: 208 EIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGY 267
Query: 355 FLIQVYVPCILIVVLSWVSFWIHRE 379
F+IQ+Y PCI+ V+LS VSFWI++E
Sbjct: 268 FMIQIYTPCIMTVILSQVSFWINKE 292
Score = 37.5 bits (83), Expect = 0.89
Identities = 14/26 (53%), Positives = 20/26 (76%)
Query: 495 SHIDRAARVLFPASFALLNLFYWMIY 520
S ID+ +R+LFP +FA NL YW++Y
Sbjct: 440 SKIDQYSRILFPVAFAGFNLVYWVVY 465
>UniRef50_Q99928 Cluster: Gamma-aminobutyric acid receptor subunit
gamma-3 precursor (GABA(A) receptor subunit gamma-3);
n=106; Euteleostomi|Rep: Gamma-aminobutyric acid
receptor subunit gamma-3 precursor (GABA(A) receptor
subunit gamma-3) - Homo sapiens (Human)
Length = 467
Score = 223 bits (546), Expect = 7e-57
Identities = 105/236 (44%), Positives = 145/236 (61%), Gaps = 2/236 (0%)
Query: 145 NITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 204
++T +L LL+ Y+ P G PTV+ +I + S+GPVS ++M+Y +D +F Q W D
Sbjct: 46 DVTLILNKLLREYDKKLRPDIGIK-PTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 205 TRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
+RL F ++ L+L+ M+ IW PDT F N K + H IT PN+LLRI G ILY++R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW-QNSQSVNFVPGMTLSQFDLI 323
LTI A+C ++L NFPMD SCPLI SY Y ++++Y+W +NS L QFD +
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFM 224
Query: 324 SFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
T GD+ V+ + F L R GYF IQ Y+PCIL VVLSWVSFWI ++
Sbjct: 225 GLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKD 280
Score = 35.5 bits (78), Expect = 3.6
Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
Query: 488 RGHINSVSHIDRAARVLFPASFALLNLFYWMIYAF 522
R HI+ + +D +RV FP SF L NL YW+ Y +
Sbjct: 433 RIHID-ILELDSYSRVFFPTSFLLFNLVYWVGYLY 466
>UniRef50_O75311 Cluster: Glycine receptor subunit alpha-3
precursor; n=128; Euteleostomi|Rep: Glycine receptor
subunit alpha-3 precursor - Homo sapiens (Human)
Length = 464
Score = 204 bits (499), Expect = 4e-51
Identities = 97/223 (43%), Positives = 140/223 (62%), Gaps = 2/223 (0%)
Query: 167 KGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLG-PIRSLSLSIKMLER 225
KG P V NI I S G ++E MDY ++ + RQ W D RL++ P SL L ML+
Sbjct: 66 KGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDS 125
Query: 226 IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSC 285
IW+PD +F N K + H +T NKLLRI ++G++LYS+RLT+ CPM+L+NFPMD Q+C
Sbjct: 126 IWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTC 185
Query: 286 PLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDL-ISFPYRNFTFTRREGDFSVLQV 344
+ L S+ Y+ L+++WQ+ V G+TL QF L R T G F+ ++V
Sbjct: 186 IMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEV 245
Query: 345 SFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVI 387
F+L+R GY+LIQ+Y+P +LIV+LSWVSFWI+ + + +
Sbjct: 246 RFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVAL 288
Score = 36.3 bits (80), Expect = 2.1
Identities = 13/30 (43%), Positives = 19/30 (63%)
Query: 491 INSVSHIDRAARVLFPASFALLNLFYWMIY 520
I+ ID +R FP +F + N+FYW+IY
Sbjct: 422 IDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
>UniRef50_P47870-2 Cluster: Isoform Long of P47870 ; n=22;
Eumetazoa|Rep: Isoform Long of P47870 - Homo sapiens
(Human)
Length = 512
Score = 203 bits (496), Expect = 8e-51
Identities = 96/254 (37%), Positives = 154/254 (60%), Gaps = 3/254 (1%)
Query: 136 RSINDAVSKNITS-VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSM 194
+S+ND + ++ ++ LLK Y+ P G G P V NI I S+ VSE++MDY++
Sbjct: 25 QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFG-GPPVAVGMNIDIASIDMVSEVNMDYTL 83
Query: 195 DCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRIS 254
YF+Q WRD RLS+ +L+L ++ +++W PDTYF N K S+VH +TV N+++R+
Sbjct: 84 TMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLH 143
Query: 255 QHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQ-NSQSVNFVP 313
G +LY +R+T A C M+LR +P+D Q+C L + SY Y+ + + W+ + +V V
Sbjct: 144 PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVT 203
Query: 314 GMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVS 373
+ L QF ++ + G + L +SF LKR+ GYF++Q Y+P ILI +LSWVS
Sbjct: 204 KIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVS 263
Query: 374 FWIHREVGSGEIVI 387
FWI+ + + + +
Sbjct: 264 FWINYDASAARVAL 277
Score = 35.9 bits (79), Expect = 2.7
Identities = 15/45 (33%), Positives = 25/45 (55%)
Query: 476 RYRRQRQREAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
R RR+ + + + V+ IDR +R+ FP F+ N+ YW+ Y
Sbjct: 466 RLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYY 510
>UniRef50_O18276 Cluster: Gamma-aminobutyric acid receptor subunit
beta precursor (GABA(A) receptor subunit beta); n=3;
Rhabditida|Rep: Gamma-aminobutyric acid receptor subunit
beta precursor (GABA(A) receptor subunit beta) -
Caenorhabditis elegans
Length = 550
Score = 203 bits (495), Expect = 1e-50
Identities = 96/245 (39%), Positives = 145/245 (59%), Gaps = 3/245 (1%)
Query: 145 NITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 204
N +S+L +LL +Y+ P G G ++ +I+I S +SE+DMDY++ Y QYW D
Sbjct: 53 NASSLLSDLLLDYDIRLRPGFG-GDALLLTMDIIIASFDSISEVDMDYTLTMYLHQYWTD 111
Query: 205 TRLSFLG--PIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYS 262
RL + PI ++LS + + IW PDT+ N KHSY+H +T NK+LRI+ G + Y
Sbjct: 112 ERLRWSNEIPIDEMTLSGEFSQNIWVPDTFLANDKHSYLHEVTERNKMLRINVDGKVAYG 171
Query: 263 MRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDL 322
MRLT C M LRNFP+D Q+C + + SY Y+ +++ +W +V+ V + QF +
Sbjct: 172 MRLTSTLSCSMNLRNFPLDSQNCTVEIESYGYTTSEVLMKWNYPLAVHGVEQADVPQFTI 231
Query: 323 ISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGS 382
F + + G + L + F L+R GYF+ Q Y+PC+LIV+LSWVSFWI+ E S
Sbjct: 232 TGFHTEDSIVSTATGSYQRLSLVFQLRRSVGYFIFQTYLPCVLIVMLSWVSFWINHEATS 291
Query: 383 GEIVI 387
+ +
Sbjct: 292 ARVAL 296
Score = 37.9 bits (84), Expect = 0.68
Identities = 16/41 (39%), Positives = 24/41 (58%)
Query: 480 QRQREAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
+R R+ + V+ ID+ +RV+FP F + NLFYW Y
Sbjct: 505 RRARKVIPTIRVRDVNLIDKYSRVVFPVCFIVFNLFYWSYY 545
>UniRef50_A2BGE6 Cluster: Glycine receptor, alpha 4b; n=5; Danio
rerio|Rep: Glycine receptor, alpha 4b - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 536
Score = 198 bits (482), Expect = 4e-49
Identities = 94/221 (42%), Positives = 135/221 (61%), Gaps = 2/221 (0%)
Query: 167 KGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLG-PIRSLSLSIKMLER 225
KG P V NI I S G ++E MDY ++ + RQ W D RL++ P SL L ML+
Sbjct: 110 KGPPVNVTCNIFINSFGSITETTMDYRLNVFLRQQWNDPRLAYKEYPDDSLDLDPSMLDS 169
Query: 226 IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSC 285
IW+PD +F N K + H +T NKLLRI Q+G++LYS+RLT+ CPM+L+NFPMD Q+C
Sbjct: 170 IWKPDLFFANEKGANFHEVTTDNKLLRIFQNGNVLYSIRLTLILSCPMDLKNFPMDTQTC 229
Query: 286 PLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRNF-TFTRREGDFSVLQV 344
+ L S+ Y+ L++QW + V + L QF L + T G F+ ++V
Sbjct: 230 TMQLESFGYTMNDLIFQWLDEGPVQVADDLMLPQFVLKEEKDLGYCTKHYNTGKFTCIEV 289
Query: 345 SFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEI 385
F+L+R GY+LIQ+Y+P +L V+LSWVSFWI+ + +
Sbjct: 290 KFHLERQMGYYLIQMYIPSLLTVILSWVSFWINMDAAPARV 330
Score = 36.3 bits (80), Expect = 2.1
Identities = 13/33 (39%), Positives = 19/33 (57%)
Query: 488 RGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
R + ID +R +FP SF + N+FYW+ Y
Sbjct: 490 RRFVEQAKRIDTISRAVFPLSFLVFNVFYWVTY 522
>UniRef50_P78334 Cluster: Gamma-aminobutyric acid receptor subunit
epsilon precursor (GABA(A) receptor subunit epsilon);
n=30; Eutheria|Rep: Gamma-aminobutyric acid receptor
subunit epsilon precursor (GABA(A) receptor subunit
epsilon) - Homo sapiens (Human)
Length = 506
Score = 198 bits (482), Expect = 4e-49
Identities = 92/232 (39%), Positives = 138/232 (59%), Gaps = 2/232 (0%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L +L NY++ P G+ PTVV I + S+GP+S LDM+Y++D F Q W D RL
Sbjct: 74 ILNTILSNYDHKLRPGIGEK-PTVVTVEISVNSLGPLSILDMEYTIDIIFSQTWYDERLC 132
Query: 209 FLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIK 268
+ SL L+ ++ ++W PDT+F N K ++ H IT+PN+++RI + G +LY++R+TI
Sbjct: 133 YNDTFESLVLNGNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTID 192
Query: 269 AKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQ-SVNFVPGMTLSQFDLISFPY 327
A C + + FPMD SCPL S++Y +++Y+W+N + +N L QFD
Sbjct: 193 AGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTGVSN 252
Query: 328 RNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
+ T GDF V+ + FN+ R GY Q YVP + +LSWVSFWI E
Sbjct: 253 KTEIITTPVGDFMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTE 304
>UniRef50_P18505 Cluster: Gamma-aminobutyric acid receptor subunit
beta-1 precursor (GABA(A) receptor subunit beta-1);
n=104; Euteleostomi|Rep: Gamma-aminobutyric acid
receptor subunit beta-1 precursor (GABA(A) receptor
subunit beta-1) - Homo sapiens (Human)
Length = 474
Score = 196 bits (478), Expect = 1e-48
Identities = 90/243 (37%), Positives = 146/243 (60%), Gaps = 2/243 (0%)
Query: 146 ITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDT 205
+ ++ LLK Y+ P G G P V I + S+ VSE++MDY++ YF+Q W+D
Sbjct: 37 VKETVDRLLKGYDIRLRPDFG-GPPVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDK 95
Query: 206 RLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRL 265
RLS+ G +L+L ++ +++W PDTYF N K S+VH +TV N+++R+ G +LY +R+
Sbjct: 96 RLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRI 155
Query: 266 TIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQ-SVNFVPGMTLSQFDLIS 324
T A C M+LR +P+D Q+C L + SY Y+ + + W + +V V + L QF ++
Sbjct: 156 TTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVD 215
Query: 325 FPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGE 384
+ + G + L +SF LKR+ GYF++Q Y+P LI +LSWVSFWI+ + +
Sbjct: 216 YKMVSKKVEFTTGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAAR 275
Query: 385 IVI 387
+ +
Sbjct: 276 VAL 278
Score = 36.3 bits (80), Expect = 2.1
Identities = 15/45 (33%), Positives = 26/45 (57%)
Query: 476 RYRRQRQREAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
R RR+ + + V+ ID+ +R+ FP +F+L N+ YW+ Y
Sbjct: 428 RIRRRASQLKVKIPDLTDVNSIDKWSRMFFPITFSLFNVVYWLYY 472
>UniRef50_UPI00015B58ED Cluster: PREDICTED: similar to GABA-gated
ion channel; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to GABA-gated ion channel - Nasonia vitripennis
Length = 513
Score = 193 bits (470), Expect = 1e-47
Identities = 93/243 (38%), Positives = 140/243 (57%), Gaps = 2/243 (0%)
Query: 145 NITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 204
N+T + +L Y+ P G G P V+ ++ I S +SE++MDY++ Y QYW+D
Sbjct: 50 NVTQTISRILDGYDIRLRPNFG-GDPLFVEMDLTIASFDAISEVNMDYTITMYLNQYWKD 108
Query: 205 TRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
RL+F L+LS E+IW PDT+F N KHS++H +T NKL+R++ G + Y MR
Sbjct: 109 ERLAFSHEKEILTLSGDFAEKIWVPDTFFANDKHSFLHDVTERNKLVRLAGDGSVTYGMR 168
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLIS 324
T C M+L +P+D Q+C + + SY Y+ +V W+ + V V L QF +I
Sbjct: 169 FTTTLACMMDLHYYPLDSQNCTVEIESYGYTVLDVVMSWKET-PVRGVDEAKLPQFTIIG 227
Query: 325 FPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGE 384
+ + G + L +SF L+R+ GYF+ Q Y+P ILIV+LSWVSFWI+ E S
Sbjct: 228 YETNDRKEKLATGIYQRLSLSFKLQRNIGYFVFQTYLPSILIVMLSWVSFWINHEATSAR 287
Query: 385 IVI 387
+ +
Sbjct: 288 VAL 290
Score = 36.7 bits (81), Expect = 1.6
Identities = 14/30 (46%), Positives = 20/30 (66%)
Query: 491 INSVSHIDRAARVLFPASFALLNLFYWMIY 520
I V+ ID+ +R++FP SF L N YW+ Y
Sbjct: 482 IKDVNLIDKYSRIIFPVSFMLFNAGYWIFY 511
>UniRef50_Q2PMX5 Cluster: GABA receptor; n=1; Tetranychus
urticae|Rep: GABA receptor - Tetranychus urticae
(Two-spotted spider mite)
Length = 585
Score = 191 bits (466), Expect = 3e-47
Identities = 90/213 (42%), Positives = 126/213 (59%), Gaps = 2/213 (0%)
Query: 168 GYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGP--IRSLSLSIKMLER 225
G P V + I ++ VSE+ MD++ D YFRQ WRD+RLSF I + + ++ ++
Sbjct: 67 GPPVKVGVTMHILTISSVSEVQMDFTADFYFRQLWRDSRLSFKARHGISQILVDAEVADK 126
Query: 226 IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSC 285
IW PDT+F N K +Y H T N LRIS G +L S+RLT+ A CPM L+ FPMDRQ C
Sbjct: 127 IWVPDTFFANEKQAYFHEATTKNTFLRISHDGQVLRSIRLTVTASCPMNLQYFPMDRQKC 186
Query: 286 PLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFSVLQVS 345
+ + SY YS ++Y W + +V + L QF + S + G++S L
Sbjct: 187 NIEIESYGYSMTDIIYNWVDENAVKIDSNLMLPQFSIASIRQSWKYISLTTGNYSRLMCE 246
Query: 346 FNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHR 378
L R GY++IQ+YVP LIV++SWVSFW+HR
Sbjct: 247 IQLTRSMGYYMIQIYVPASLIVIISWVSFWLHR 279
Score = 35.9 bits (79), Expect = 2.7
Identities = 14/28 (50%), Positives = 19/28 (67%)
Query: 493 SVSHIDRAARVLFPASFALLNLFYWMIY 520
S S ID+ +RV+FP F NL YW+I+
Sbjct: 543 SPSDIDKYSRVVFPVCFVCFNLMYWIIF 570
>UniRef50_A7SLK4 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 319
Score = 189 bits (460), Expect = 2e-46
Identities = 94/249 (37%), Positives = 141/249 (56%), Gaps = 7/249 (2%)
Query: 145 NITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 204
N T VL+NLL+ Y+ P KG P VV ++ + ++ + E++MD+++D Y RQYWRD
Sbjct: 21 NSTLVLKNLLEGYDRRIRPG-SKGEPVVVYVDMYVSNIWAMQEMNMDFTIDIYLRQYWRD 79
Query: 205 TRLSF--LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYS 262
RL F P L+LS + ++IW P TYF K +Y H +T N LL++ G + YS
Sbjct: 80 ERLQFETQTPGAMLTLSSDINKQIWVPSTYFLATKKAYFHDVTTDNYLLQVKPDGSLFYS 139
Query: 263 MRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW----QNSQSVNFVPGMTLS 318
+RLTI C ++LR+FP D QSC L L SY Y + ++Y W N+ ++ + L
Sbjct: 140 IRLTITTSCRLDLRDFPHDTQSCSLSLESYGYQSTDVLYVWNERLDNTSAIYIHDDLELP 199
Query: 319 QFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHR 378
QF+++ G+ S L +F +KR GYFLI Y+P +IV++SW+SFWI
Sbjct: 200 QFEVLGVSRSAKMNKYNIGNHSSLVANFRMKRRIGYFLIDTYIPSTIIVIISWISFWIDP 259
Query: 379 EVGSGEIVI 387
E + +
Sbjct: 260 ETAPARVAL 268
>UniRef50_P25123 Cluster: Gamma-aminobutyric acid receptor subunit
beta precursor (GABA(A) receptor subunit beta); n=45;
Pancrustacea|Rep: Gamma-aminobutyric acid receptor
subunit beta precursor (GABA(A) receptor subunit beta) -
Drosophila melanogaster (Fruit fly)
Length = 606
Score = 186 bits (454), Expect = 1e-45
Identities = 90/246 (36%), Positives = 142/246 (57%), Gaps = 4/246 (1%)
Query: 145 NITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 204
NI+++L++ +Y+ P +G G P V + + S+ VSE+ MD+++D YFRQ+W D
Sbjct: 58 NISAILDSFSVSYDKRVRPNYG-GPPVEVGVTMYVLSISSVSEVLMDFTLDFYFRQFWTD 116
Query: 205 TRLSFLGP--IRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYS 262
RL++ + +LS+ + ++ IW PDT+F N K SY H T N+ +R+ G I S
Sbjct: 117 PRLAYRKRPGVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRS 176
Query: 263 MRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNS-QSVNFVPGMTLSQFD 321
+RLTI A CPM L+ FPMDRQ C + + S+ Y+ + + Y W++ SV + L QF
Sbjct: 177 IRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYFWRDGLSSVGMSSEVELPQFR 236
Query: 322 LISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
++ R G++S L R GY+LIQ+Y+P LIV++SWVSFW++R
Sbjct: 237 VLGHRQRATEINLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNAT 296
Query: 382 SGEIVI 387
+ +
Sbjct: 297 PARVAL 302
Score = 38.7 bits (86), Expect = 0.39
Identities = 15/31 (48%), Positives = 20/31 (64%)
Query: 495 SHIDRAARVLFPASFALLNLFYWMIYAFSSD 525
S ID+ +R++FP F NL YW+IY SD
Sbjct: 564 SDIDKYSRIVFPVCFVCFNLMYWIIYLHVSD 594
>UniRef50_A7SFG6 Cluster: Predicted protein; n=4; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 424
Score = 185 bits (450), Expect = 3e-45
Identities = 98/246 (39%), Positives = 141/246 (57%), Gaps = 7/246 (2%)
Query: 146 ITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDT 205
+TS+L+NL++ Y+ P G G P V + S+ ++ +DMDY MD + RQ WRD
Sbjct: 6 MTSLLDNLIQGYDPRLRPDFG-GDPVTVTVGFWVLSIDAINVIDMDYRMDFFLRQLWRDP 64
Query: 206 RLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRL 265
RL +L+LS ML++IW PDTYF N K S H++T NK+L IS G + Y+ R+
Sbjct: 65 RLKHRFD-DTLALSNTMLDKIWVPDTYFVNSKMSKFHSVTTINKMLSISPDGLVHYNSRV 123
Query: 266 TIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPG---MTLSQFDL 322
T+KA C M LR FP D Q+C + + SY YS + YQW+N + Q++L
Sbjct: 124 TVKASCAMNLRMFPKDVQNCNIDIESYGYSADNVQYQWENRSDNGIAVNKKIRDMPQYNL 183
Query: 323 ISFPY-RNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
R+FT G++S L +F +R +GYF+I +Y PC LIV+LSW+SF I E
Sbjct: 184 SDINVSRHFTM-YVAGNWSGLTATFRFRRRSGYFIIHIYAPCALIVILSWISFCIPPEST 242
Query: 382 SGEIVI 387
+ I +
Sbjct: 243 AARIAL 248
>UniRef50_UPI00006A0B5C Cluster: Gamma-aminobutyric-acid receptor
subunit alpha-3 precursor (GABA(A) receptor subunit
alpha-3).; n=2; Xenopus tropicalis|Rep:
Gamma-aminobutyric-acid receptor subunit alpha-3
precursor (GABA(A) receptor subunit alpha-3). - Xenopus
tropicalis
Length = 465
Score = 183 bits (445), Expect = 1e-44
Identities = 100/238 (42%), Positives = 140/238 (58%), Gaps = 9/238 (3%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQ-TNILIRSMGP-VSELDM---DYSMDCYFRQYWR 203
+L+ LL Y+N P G G P + I S G V +++M +Y++D +FRQ W
Sbjct: 40 ILDRLLDGYDNRLRP--GLGAPNKGRHIRGKICSFGDLVKQVNMPSLEYTIDVFFRQSWL 97
Query: 204 DTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSM 263
D RL F GPIR+L L+ + +IW PDT+F+NGK S H +T PNKLLR+ +G +LY+M
Sbjct: 98 DERLKFDGPIRTLPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLIDNGTLLYTM 157
Query: 264 RLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLI 323
RLTI A+C M L +FPMD +CPL GS Y N+Q+ + + L F I
Sbjct: 158 RLTIHAECTMHLEDFPMDVHACPLKFGSCMYCNEQVSFYCHIDSDFPGQVAVHLHYFFSI 217
Query: 324 SFPYRNFTFT--RREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
Y + G++ V+ F+LKR GYF+IQ Y+PCI+ V+LS VSFW++RE
Sbjct: 218 ITYYSAISSNCCSSLGEYIVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 275
Score = 41.9 bits (94), Expect = 0.041
Identities = 16/29 (55%), Positives = 21/29 (72%)
Query: 492 NSVSHIDRAARVLFPASFALLNLFYWMIY 520
NSVS ID+ +R++FP FA+ NL YW Y
Sbjct: 435 NSVSRIDKISRIVFPVLFAIFNLVYWATY 463
>UniRef50_UPI0000E4758B Cluster: PREDICTED: similar to GABA-gated
chloride channel; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to GABA-gated
chloride channel - Strongylocentrotus purpuratus
Length = 530
Score = 182 bits (443), Expect = 2e-44
Identities = 87/239 (36%), Positives = 133/239 (55%), Gaps = 2/239 (0%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L + Y+ P G G P V ++ + SMGP++E M+Y++D YFRQ WRD RL
Sbjct: 52 ILNRIFDGYDKRLRPGFG-GPPIDVTVSMYVYSMGPITESKMEYTLDMYFRQQWRDERLQ 110
Query: 209 FLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIK 268
F + L+L+ + L+ W PD Y N K + HT+ N LLRI G++L+S RLT+
Sbjct: 111 FDSEV-GLALNAETLDSFWVPDIYIINEKSAAYHTVLYKNSLLRIEPTGEMLFSTRLTVT 169
Query: 269 AKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYR 328
A C M+L FP D+Q C L + SYAYS + ++W + V P ++L QF + R
Sbjct: 170 ASCNMDLSTFPFDKQRCSLDMESYAYSEDDVKFKWLENGPVYVDPKISLPQFKFLDSSVR 229
Query: 329 NFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVI 387
+ G+++V+ F L R Y+++Q Y+P +I LSW+SFWI+R + +
Sbjct: 230 SRIAEYFVGNYTVVSADFYLGRDITYYVVQTYIPSSMITCLSWLSFWINRNAVPARVAL 288
Score = 36.7 bits (81), Expect = 1.6
Identities = 13/24 (54%), Positives = 18/24 (75%)
Query: 497 IDRAARVLFPASFALLNLFYWMIY 520
+D+ ARV FP +F LNL YW++Y
Sbjct: 491 VDKVARVAFPLTFFSLNLVYWLVY 514
>UniRef50_O14764 Cluster: Gamma-aminobutyric acid receptor subunit
delta precursor (GABA(A) receptor subunit delta); n=27;
Euteleostomi|Rep: Gamma-aminobutyric acid receptor
subunit delta precursor (GABA(A) receptor subunit delta)
- Homo sapiens (Human)
Length = 452
Score = 182 bits (442), Expect = 3e-44
Identities = 86/229 (37%), Positives = 137/229 (59%), Gaps = 3/229 (1%)
Query: 150 LENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF 209
L+ L+ Y + P G G P V + + S+ +SE +M+Y+M + Q WRD+RLS+
Sbjct: 44 LDGLIAGYARNFRPGIG-GPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSY 102
Query: 210 LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKA 269
+L L + ++++W PDT+ N K ++ H +TV NKL+R+ G ILYS+R+T
Sbjct: 103 NHTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTV 162
Query: 270 KCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQS-VNFVPGMTLSQFDLISFPYR 328
C M+L +PMD Q C L L SY YS++ +VY W SQ ++ + + L+QF + S+ +
Sbjct: 163 ACDMDLAKYPMDEQECMLDLESYGYSSEDIVYYWSESQEHIHGLDKLQLAQFTITSYRFT 222
Query: 329 NFTFT-RREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
+ G F L + F+L+R+ G ++IQ Y+P +L+V +SWVSFWI
Sbjct: 223 TELMNFKSAGQFPRLSLHFHLRRNRGVYIIQSYMPSVLLVAMSWVSFWI 271
Score = 35.1 bits (77), Expect = 4.8
Identities = 14/25 (56%), Positives = 18/25 (72%)
Query: 497 IDRAARVLFPASFALLNLFYWMIYA 521
ID AR +FPA+FA +N+ YW YA
Sbjct: 427 IDIYARAVFPAAFAAVNVIYWAAYA 451
>UniRef50_UPI000065FF28 Cluster: Gamma-aminobutyric-acid receptor
subunit rho-1 precursor (GABA(A) receptor subunit
rho-1).; n=1; Takifugu rubripes|Rep:
Gamma-aminobutyric-acid receptor subunit rho-1 precursor
(GABA(A) receptor subunit rho-1). - Takifugu rubripes
Length = 477
Score = 180 bits (439), Expect = 7e-44
Identities = 89/242 (36%), Positives = 149/242 (61%), Gaps = 6/242 (2%)
Query: 142 VSKNITSVLENLLK--NYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFR 199
V+K+ + E+LL+ +++ + P G G V ++ + S+ +SE+DMD++M Y R
Sbjct: 50 VTKSRKTKTEHLLQVDDHDFTMRPAFG-GPAIPVGVDVQVESLDSISEVDMDFTMTLYLR 108
Query: 200 QYWRDTRLSFLGPI-RSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGD 258
YW+D RLSF +S++ +++++IW PD +F + K S++H T N +LR+ G
Sbjct: 109 HYWKDERLSFRSSTNKSMTFDGRLVKKIWVPDVFFVHSKRSFIHDTTTDNIMLRVFPDGH 168
Query: 259 ILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQN-SQSVNFVPGMTL 317
+LYS+R+T+ A C M+ FP+D Q+C L L SYAY+++ L+ W++ +S++ ++L
Sbjct: 169 VLYSLRVTVTAACNMDFSRFPLDTQTCTLELESYAYTDEDLMLYWKSGDESLSIDDRISL 228
Query: 318 SQFDLISF-PYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
SQF + F F G ++ L ++F L+RH +FL+Q Y P L+V+LSWVSFWI
Sbjct: 229 SQFLIQKFHTTSRLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWI 288
Query: 377 HR 378
R
Sbjct: 289 DR 290
Score = 35.1 bits (77), Expect = 4.8
Identities = 12/30 (40%), Positives = 19/30 (63%)
Query: 491 INSVSHIDRAARVLFPASFALLNLFYWMIY 520
I + ID+ +R++FP S+ NL YW +Y
Sbjct: 447 IQNTHAIDKYSRMIFPGSYIFFNLIYWSVY 476
>UniRef50_Q08832 Cluster: Gamma-aminobutyric acid receptor subunit
beta-like precursor (GABA(A) receptor); n=11;
Protostomia|Rep: Gamma-aminobutyric acid receptor
subunit beta-like precursor (GABA(A) receptor) -
Drosophila melanogaster (Fruit fly)
Length = 496
Score = 180 bits (438), Expect = 9e-44
Identities = 95/256 (37%), Positives = 142/256 (55%), Gaps = 14/256 (5%)
Query: 144 KNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWR 203
+N+T + N+L+ Y+ P G G P V ++ I S +SE++MDY++ Y QYWR
Sbjct: 38 ENVTQTISNILQGYDIRLRPNFG-GEPLHVGMDLTIASFDAISEVNMDYTITMYLNQYWR 96
Query: 204 DTRLSFL------------GPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLL 251
D RL+F G L+LS E+IW PDT+F N K+S++H +T NKL+
Sbjct: 97 DERLAFNIFGQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFANDKNSFLHDVTERNKLV 156
Query: 252 RISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNF 311
R+ G + Y MR T C M+L +P+D Q+C + + SY Y+ +V W+ + V
Sbjct: 157 RLGGDGAVTYGMRFTTTLACMMDLHYYPLDSQNCTVEIESYGYTVSDVVMYWKPT-PVRG 215
Query: 312 VPGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSW 371
V L QF +I + + G + L +SF L+R+ GYF+ Q Y+P ILIV+LSW
Sbjct: 216 VEDAELPQFTIIGYETNDRKERLATGVYQRLSLSFKLQRNIGYFVFQTYLPSILIVMLSW 275
Query: 372 VSFWIHREVGSGEIVI 387
VSFWI+ E S + +
Sbjct: 276 VSFWINHEATSARVAL 291
Score = 35.9 bits (79), Expect = 2.7
Identities = 14/30 (46%), Positives = 20/30 (66%)
Query: 491 INSVSHIDRAARVLFPASFALLNLFYWMIY 520
I V+ ID+ +R++FP SF NL YW+ Y
Sbjct: 464 IKDVNIIDKYSRMIFPISFLAFNLGYWLFY 493
>UniRef50_P28476 Cluster: Gamma-aminobutyric acid receptor subunit
rho-2 precursor (GABA(A) receptor subunit rho-2); n=99;
Euteleostomi|Rep: Gamma-aminobutyric acid receptor
subunit rho-2 precursor (GABA(A) receptor subunit rho-2)
- Homo sapiens (Human)
Length = 465
Score = 178 bits (434), Expect = 3e-43
Identities = 86/225 (38%), Positives = 137/225 (60%), Gaps = 4/225 (1%)
Query: 157 YENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPI-RS 215
++ S P G G V ++ + S+ +SE+DMD++M Y R YW+D RL+F +S
Sbjct: 64 HDFSMRPAFG-GPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSASNKS 122
Query: 216 LSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMEL 275
++ +++++IW PD +F + K S+ H T N +LR+ G +LYSMR+T+ A C M+
Sbjct: 123 MTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDF 182
Query: 276 RNFPMDRQSCPLILGSYAYSNQQLVYQWQN-SQSVNFVPGMTLSQFDLISF-PYRNFTFT 333
+FP+D Q+C L L SYAY+++ L+ W+N +S+ ++LSQF + F F
Sbjct: 183 SHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFY 242
Query: 334 RREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHR 378
G ++ L ++F L+RH +FL+Q Y P L+V+LSWVSFWI R
Sbjct: 243 SSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDR 287
Score = 36.3 bits (80), Expect = 2.1
Identities = 18/53 (33%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
Query: 471 LAGDDRYRRQRQREAGSRG-HINSVSH-IDRAARVLFPASFALLNLFYWMIYA 521
L+G+ R++ G G I +H ID+ +R++FPAS+ NL YW +++
Sbjct: 413 LSGEANAARKKGLLKGQTGFRIFQNTHAIDKYSRLIFPASYIFFNLIYWSVFS 465
>UniRef50_UPI00015B4D8A Cluster: PREDICTED: similar to
glutamate-gated chloride channel; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to glutamate-gated
chloride channel - Nasonia vitripennis
Length = 510
Score = 177 bits (430), Expect = 8e-43
Identities = 85/235 (36%), Positives = 137/235 (58%), Gaps = 9/235 (3%)
Query: 149 VLENLLK--NYENSQLPT--HGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 204
VL+N+L +Y+ P+ +G P +V+ N+ +RS+ +S++ M+YS+ FR+ W D
Sbjct: 37 VLDNILGPGSYDARIRPSGENGTDGPAIVRVNLFVRSIATISDIKMEYSVQLTFREQWVD 96
Query: 205 TRLSFL---GPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILY 261
RL F G ++ L+L+ R+W PD +F N K + H I +PN +RI G +LY
Sbjct: 97 ERLRFNDFGGKLKYLTLTDA--SRVWMPDLFFANEKEGHFHNIIMPNVYIRIFPDGSVLY 154
Query: 262 SMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFD 321
S+R+++ CPM L+ +P+DRQ C L + SY ++ LV+ W+ V V + L +F
Sbjct: 155 SIRISLTLSCPMNLKLYPLDRQICSLRMASYGWTTADLVFLWKEGDPVQVVKNLHLPRFT 214
Query: 322 LISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
L F G++S L+V KR Y+LIQ+Y+PC ++V++SWVSFW+
Sbjct: 215 LEKFLTDYCNSKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWL 269
Score = 37.5 bits (83), Expect = 0.89
Identities = 15/30 (50%), Positives = 19/30 (63%)
Query: 497 IDRAARVLFPASFALLNLFYWMIYAFSSDD 526
ID AR++FP FAL NL YW Y F ++
Sbjct: 417 IDVIARIIFPLVFALFNLAYWSTYLFREEE 446
>UniRef50_UPI0000E47589 Cluster: PREDICTED: similar to
gamma-aminobutyric acid A receptor beta 2S chain
precursor - chicken; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to gamma-aminobutyric
acid A receptor beta 2S chain precursor - chicken -
Strongylocentrotus purpuratus
Length = 418
Score = 176 bits (429), Expect = 1e-42
Identities = 84/196 (42%), Positives = 121/196 (61%), Gaps = 1/196 (0%)
Query: 191 DYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKL 250
DY++ YFRQ+W+D RLS+ + ++SLS + ERIW PDTYF N K S+VH +TV NKL
Sbjct: 3 DYTLTMYFRQHWKDERLSYDPCLGNVSLSGILAERIWVPDTYFPNDKRSFVHDVTVTNKL 62
Query: 251 LRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQ-NSQSV 309
LR G I Y MR+T A C M+L ++PMD Q+C L + SY Y+ + + WQ S+
Sbjct: 63 LRFHHDGTITYGMRITSVASCYMDLVHYPMDEQNCSLEIESYGYTTADVNFVWQYGDDSL 122
Query: 310 NFVPGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVL 369
V + ++QF L + G + L ++F +KR+ G+F +Q Y+P IL+V+L
Sbjct: 123 EGVNNIEMAQFTLSDYKLIVKMQNFSTGSYPRLALTFRIKRNVGFFFLQTYLPSILLVML 182
Query: 370 SWVSFWIHREVGSGEI 385
SWVSFWI+ E S +
Sbjct: 183 SWVSFWINHEATSARV 198
Score = 39.9 bits (89), Expect = 0.17
Identities = 16/47 (34%), Positives = 28/47 (59%)
Query: 476 RYRRQRQREAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIYAF 522
R R+++ + I +V+ +DR +R+LFP F L N+ YW+ Y +
Sbjct: 363 RRRKKKPKRIRVLPRIRNVNTVDRVSRILFPFLFLLFNVLYWVGYLY 409
>UniRef50_Q94900 Cluster: Glutamate-gated chloride channel
precursor; n=21; Pancrustacea|Rep: Glutamate-gated
chloride channel precursor - Drosophila melanogaster
(Fruit fly)
Length = 456
Score = 176 bits (428), Expect = 1e-42
Identities = 79/215 (36%), Positives = 127/215 (59%), Gaps = 5/215 (2%)
Query: 165 HGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF---LGPIRSLSLSIK 221
+G P +V+ N+ +RS+ +S++ M+YS+ FR+ W D RL F G ++ L+L+
Sbjct: 56 NGTDGPAIVRINLFVRSIMTISDIKMEYSVQLTFREQWTDERLKFDDIQGRLKYLTLT-- 113
Query: 222 MLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMD 281
R+W PD +F N K + H I +PN +RI +G +LYS+R+++ CPM L+ +P+D
Sbjct: 114 EANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLD 173
Query: 282 RQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFSV 341
RQ C L + SY ++ LV+ W+ V V + L +F L F G++S
Sbjct: 174 RQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRFTLEKFLTDYCNSKTNTGEYSC 233
Query: 342 LQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
L+V KR Y+LIQ+Y+PC ++V++SWVSFW+
Sbjct: 234 LKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWL 268
Score = 35.5 bits (78), Expect = 3.6
Identities = 14/30 (46%), Positives = 18/30 (60%)
Query: 497 IDRAARVLFPASFALLNLFYWMIYAFSSDD 526
ID +R+ FP FAL NL YW Y F ++
Sbjct: 425 IDVISRITFPLVFALFNLVYWSTYLFREEE 454
>UniRef50_A7S5Y7 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 304
Score = 175 bits (426), Expect = 2e-42
Identities = 86/236 (36%), Positives = 140/236 (59%), Gaps = 8/236 (3%)
Query: 147 TSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTR 206
T L ++L+ YE+ P + +G P + +I + S G + E DM +S+D +FRQ W D R
Sbjct: 1 TKRLHSMLEGYESKIRPNY-QGDPVEILIDISVASFGNLQEADMKFSLDMFFRQSWHDPR 59
Query: 207 LSF-LGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
L + +L+ K + +W PDT F + H+Y+H + V N L ++ G + + R
Sbjct: 60 LRHNMNETMTLTTGTKHPADFVWVPDTVFVDASHAYMHNVMVANHKLDVTPGGRVFWGTR 119
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDL-- 322
T+ A+C M LR +PMD Q+C L + SYAY + L+Y+W+NS + + G +SQF +
Sbjct: 120 ATLIARCHMNLRRYPMDEQTCNLSIISYAYPVRHLLYRWKNSPGIKVLDG-EMSQFYMTR 178
Query: 323 ISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHR 378
I+ RN + G++SVL+ SF +R G++LIQ+Y+PC+ IV ++W+S W+ R
Sbjct: 179 ITTSLRNEIYV--AGEYSVLKASFTFQRRVGFYLIQIYIPCMAIVFVAWMSLWVDR 232
>UniRef50_Q9UN88 Cluster: Gamma-aminobutyric acid receptor subunit
theta precursor (GABA(A) receptor subunit theta); n=18;
Tetrapoda|Rep: Gamma-aminobutyric acid receptor subunit
theta precursor (GABA(A) receptor subunit theta) - Homo
sapiens (Human)
Length = 632
Score = 175 bits (426), Expect = 2e-42
Identities = 79/254 (31%), Positives = 144/254 (56%), Gaps = 5/254 (1%)
Query: 135 KRSINDAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSM 194
K N+AV + +L+ +L Y+ P G G P V+ +I + S+ +SE++MDY++
Sbjct: 51 KNCANEAV---VQKILDRVLSRYDVRLRPNFG-GAPVPVRISIYVTSIEQISEMNMDYTI 106
Query: 195 DCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRIS 254
+F Q W+D+RL++ +L+L +M E++W PD YF N K ++VH +TV N++ ++
Sbjct: 107 TMFFHQTWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLH 166
Query: 255 QHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW-QNSQSVNFVP 313
G + Y +RLT A C ++L FPMD+Q+C L++ SY Y+ + ++ W N +++
Sbjct: 167 PDGTVRYGIRLTTTAACSLDLHKFPMDKQACNLVVESYGYTVEDIILFWDDNGNAIHMTE 226
Query: 314 GMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVS 373
+ + QF + + G + L + F ++R +L+QVY P +L + SW+S
Sbjct: 227 ELHIPQFTFLGRTITSKEVYFYTGSYIRLILKFQVQREVNSYLVQVYWPTVLTTITSWIS 286
Query: 374 FWIHREVGSGEIVI 387
FW++ + + + I
Sbjct: 287 FWMNYDSSAARVTI 300
>UniRef50_A7S763 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 278
Score = 173 bits (420), Expect = 1e-41
Identities = 77/215 (35%), Positives = 135/215 (62%), Gaps = 5/215 (2%)
Query: 168 GYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF--LGPIRSLSLSIKMLER 225
G P +V T++ + +G +SE DM++ + ++RQYW+DTRL++ G + L+L+ +M++
Sbjct: 3 GDPVIVYTDMFVLDIGDISEADMEFRVMFFYRQYWQDTRLAYDYTGYNKRLALNARMVDY 62
Query: 226 IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSC 285
+W PD YF N K H +T N+++R+ G + +S+RL++ A CPM+L ++PMD+Q+C
Sbjct: 63 MWIPDIYFVNEKSGIKHDLTKQNEVVRVWPDGRVFHSIRLSMTASCPMKLHSYPMDKQTC 122
Query: 286 PLILGSYAYSNQQLVYQW---QNSQSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFSVL 342
L S++Y + +L+++W + ++ V + + QF L + + G +S L
Sbjct: 123 KLSFESFSYPSTELIFKWNKNRGNKEVQVSDELQIPQFILTEYKTTSEFANFTTGSYSRL 182
Query: 343 QVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIH 377
V F +R G+FLIQ Y+P LIV+LSW++FWI+
Sbjct: 183 TVLFRFERSIGFFLIQTYIPAYLIVMLSWIAFWIN 217
>UniRef50_P48167 Cluster: Glycine receptor subunit beta precursor;
n=34; Euteleostomi|Rep: Glycine receptor subunit beta
precursor - Homo sapiens (Human)
Length = 497
Score = 173 bits (420), Expect = 1e-41
Identities = 91/260 (35%), Positives = 144/260 (55%), Gaps = 8/260 (3%)
Query: 132 KQNKRSINDAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMD 191
+Q+ + + + +++L LL +Y+ P KG P V NI I S G + E MD
Sbjct: 42 QQSAEDLARVPANSTSNILNRLLVSYDPRIRPNF-KGIPVDVVVNIFINSFGSIQETTMD 100
Query: 192 YSMDCYFRQYWRDTRLSFLGPIR---SLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPN 248
Y ++ + RQ W D RL R +L++ M + +W+PD +F N K + H +T N
Sbjct: 101 YRVNIFLRQKWNDPRLKLPSDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQEN 160
Query: 249 KLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQS 308
LL I + GD+L SMRL+I CP++L FPMD Q C + L S+ Y+ L + WQ+
Sbjct: 161 ILLFIFRDGDVLVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDP 220
Query: 309 VNFVPGMTLSQFDL--ISFPYRNFT-FTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCIL 365
V + + L QFD+ Y N T + + G ++ ++V F L+R G++++ VY P +L
Sbjct: 221 VQ-LEKIALPQFDIKKEDIEYGNCTKYYKGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLL 279
Query: 366 IVVLSWVSFWIHREVGSGEI 385
IVVLSW+SFWI+ + + +
Sbjct: 280 IVVLSWLSFWINPDASAARV 299
>UniRef50_Q8MTJ9 Cluster: Ionotropic GABA receptor beta subunit 1b;
n=8; Pancrustacea|Rep: Ionotropic GABA receptor beta
subunit 1b - Homarus americanus (American lobster)
Length = 521
Score = 172 bits (419), Expect = 2e-41
Identities = 84/200 (42%), Positives = 123/200 (61%), Gaps = 4/200 (2%)
Query: 183 GPVSE-LDMDYSMDCYFRQYWRDTRLSF--LGPIRSLSLSIKMLERIWRPDTYFYNGKHS 239
GP S+ D+++D YFRQ+W D RLSF G + L++ + L++IW PDT+F N K S
Sbjct: 119 GPESDGPSQDFTLDFYFRQHWTDPRLSFPGRGGLDELTVGSEYLQKIWVPDTFFANEKKS 178
Query: 240 YVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQL 299
Y HT T N++LRI+ G +L S+RLTI A CPM L+ FPMDR+ C + + S+ YS +
Sbjct: 179 YFHTATTSNEMLRITNQGKVLRSIRLTITASCPMNLQYFPMDRELCIIEIESFGYSMDHI 238
Query: 300 VYQWQ-NSQSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQ 358
W +SV ++L QF ++ + + + G++S L R GY+LIQ
Sbjct: 239 RLSWHAGDRSVVIESDVSLPQFRVLGYNRKTIISSTSTGNYSRLLCEIMFVRSMGYYLIQ 298
Query: 359 VYVPCILIVVLSWVSFWIHR 378
+Y+P LIVV+SWVSFW++R
Sbjct: 299 IYIPSSLIVVISWVSFWLNR 318
Score = 41.9 bits (94), Expect = 0.041
Identities = 17/34 (50%), Positives = 22/34 (64%)
Query: 493 SVSHIDRAARVLFPASFALLNLFYWMIYAFSSDD 526
S S ID+ +R++FP F NL YW+IY SDD
Sbjct: 476 SPSDIDKYSRIVFPVCFVCFNLMYWIIYLHISDD 509
>UniRef50_O17547 Cluster: GluClalpha2A protein; n=66;
Chromadorea|Rep: GluClalpha2A protein - Caenorhabditis
elegans
Length = 657
Score = 172 bits (419), Expect = 2e-41
Identities = 88/241 (36%), Positives = 136/241 (56%), Gaps = 9/241 (3%)
Query: 147 TSVLENLL-KNYENSQLPTHGKGY----PTVVQTNILIRSMGPVSELDMDYSMDCYFRQY 201
T +LE+LL + Y++ P G P VV N+L+RS+ + ++M+YS+ FR+
Sbjct: 252 TEILEHLLTRGYDHRVRPPGEDGTIHGGPVVVSVNMLLRSISKIDNVNMEYSVQLTFRES 311
Query: 202 WRDTRLSF--LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDI 259
W D RLSF G + L + + IW PD++F N +Y H I PN L+R+ + G I
Sbjct: 312 WVDKRLSFGVKGDAQPDFLILTAGQEIWMPDSFFQNENQAYKHMIDKPNVLIRVHKDGTI 371
Query: 260 LYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGM--TL 317
LYS+R+++ CPM L+ +PMD Q C + L SYAY+ + + Y W+ V G+ +L
Sbjct: 372 LYSVRISLVLSCPMHLQYYPMDVQQCFIDLASYAYTTKDIEYVWKEETPVQLKAGLSSSL 431
Query: 318 SQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIH 377
F L + T G +S L+ L+R Y+L+Q+Y+P ++V++SWVSFWI
Sbjct: 432 PSFQLTNTSTTYCTSKTNTGSYSCLRTIIQLRRQFSYYLLQLYIPSCMLVIVSWVSFWID 491
Query: 378 R 378
R
Sbjct: 492 R 492
>UniRef50_A7SDF1 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 273
Score = 172 bits (419), Expect = 2e-41
Identities = 82/233 (35%), Positives = 137/233 (58%), Gaps = 3/233 (1%)
Query: 148 SVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRL 207
S++ L +Y+ + P G G PT++ ++ + S G + E +M+Y + +FRQYWR+ RL
Sbjct: 3 SIINKLFADYDKTLRPGDGDG-PTLITADLYVSSFGNIQETNMEYKVFGFFRQYWREDRL 61
Query: 208 SFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVH-TITVPNKLLRISQHGDILYSMRLT 266
+ +++ L+ K ++ +W+PD + N + S + T + ++ + G +LYS +
Sbjct: 62 AGKHN-KTVILTGKEIDNMWKPDPFCNNARESNLRETDESISSMVFLEPDGSVLYSRLII 120
Query: 267 IKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFP 326
+ A+C M LR FPMD Q C L L SY+Y+ + ++Y+W+ + V L+QFD+ +
Sbjct: 121 VTAECNMNLRFFPMDEQKCYLKLSSYSYTTENIIYKWKTGKPAVEVGTKDLAQFDMKTVE 180
Query: 327 YRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
N T T GDF + V+F KR GYF+IQV+ P I +V+LSW+ FW+ RE
Sbjct: 181 ISNMTDTFVTGDFEAIIVTFTFKRRLGYFIIQVFAPDIFVVMLSWIVFWMDRE 233
>UniRef50_A7S8M2 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 303
Score = 170 bits (413), Expect = 9e-41
Identities = 79/237 (33%), Positives = 138/237 (58%), Gaps = 5/237 (2%)
Query: 145 NITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 204
++ +L+ ++ Y+N PT+ P +Q ++ I+S+ S ++M+YSM Y RQ W D
Sbjct: 2 SLDELLDVMVNCYDNRVRPTYPDNGPVNIQVDLFIQSVSKFSVINMEYSMTLYIRQRWLD 61
Query: 205 TRLSF--LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYS 262
RL++ + P ++L +M+ +IW PDTY N K S ++ + +RIS++G +++S
Sbjct: 62 QRLAYGDMFPEDFITLGQEMVSQIWTPDTYIVNKKQSMTNSGHGMSMFIRISRNGSVIFS 121
Query: 263 MRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW---QNSQSVNFVPGMTLSQ 319
T+ C M+LRNFPMD Q C + SY ++ + +VY+W +++ G+ ++
Sbjct: 122 AENTLVLVCQMDLRNFPMDEQQCDFKIESYGFTMKDVVYKWLDDPKQKTIETAEGLDATE 181
Query: 320 FDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
F ++S G+FS L + L R T Y++IQ+Y+PC +IV+LSW+SFW+
Sbjct: 182 FSIVSLKTMENISVFNLGNFSSLTMRIYLDRRTTYYVIQIYIPCSMIVMLSWISFWL 238
>UniRef50_A7SJ14 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 291
Score = 169 bits (412), Expect = 1e-40
Identities = 90/240 (37%), Positives = 133/240 (55%), Gaps = 4/240 (1%)
Query: 150 LENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF 209
L+ L + + P G G P VV +I I ++G +S +MDY + Y+RQ W D RL+F
Sbjct: 2 LDRLKSSMDKRLRPFFG-GKPVVVYVDIYIVNIGEISVTNMDYKLMLYYRQTWHDPRLAF 60
Query: 210 LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKA 269
P ++++ ML IW PDT F N K S H +T N LL I +G SMR+++
Sbjct: 61 DLP-EAITVQGGMLNDIWIPDTLFTNEKSSTFHKVTQDNYLLSIWPNGTTYLSMRISLTG 119
Query: 270 KCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQ--NSQSVNFVPGMTLSQFDLISFPY 327
CPM+LR +PMD Q+C L + SY+ S L+ +W+ + SV + + L Q D++
Sbjct: 120 ICPMDLRKYPMDTQTCYLNIMSYSGSTDNLILKWKFGETGSVTWAENINLPQMDVLGVKG 179
Query: 328 RNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVI 387
R G++S L ++F KR FL + YVP +LIV LSWVSFWI+ +V + +
Sbjct: 180 REVVDVFASGNYSRLSLAFKFKRRISLFLTETYVPLVLIVALSWVSFWINYKVAPARVAL 239
>UniRef50_O00591 Cluster: Gamma-aminobutyric acid receptor subunit
pi precursor (GABA(A) receptor subunit pi); n=19;
Euteleostomi|Rep: Gamma-aminobutyric acid receptor
subunit pi precursor (GABA(A) receptor subunit pi) -
Homo sapiens (Human)
Length = 440
Score = 169 bits (412), Expect = 1e-40
Identities = 84/228 (36%), Positives = 135/228 (59%), Gaps = 5/228 (2%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL 210
ENL Y P G G P + + I S+ +SE +MDY+ Y RQ W D RL F
Sbjct: 42 ENLTAGYNKFLRPNFG-GEPVQIALTLDIASISSISESNMDYTATIYLRQRWMDQRLVFE 100
Query: 211 GPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAK 270
G +S +L +++E +W PDTY K S++H +TV N+L+R+ +G +LY++R+T
Sbjct: 101 GN-KSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVA 159
Query: 271 CPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW-QNSQSVNFVPGMTLSQFDLISFPYRN 329
C M+L +PMD Q+C L L S+ Y + + W + + SV + + L+Q+ + + +
Sbjct: 160 CNMDLSKYPMDTQTCKLQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERY-FTL 218
Query: 330 FTFTRRE-GDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
T +++E G+++ L + F L+R+ YF+++ YVP +VVLSWVSFWI
Sbjct: 219 VTRSQQETGNYTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWI 266
Score = 35.9 bits (79), Expect = 2.7
Identities = 13/32 (40%), Positives = 21/32 (65%)
Query: 491 INSVSHIDRAARVLFPASFALLNLFYWMIYAF 522
I + S++D +++LFP F L N+FYW Y +
Sbjct: 408 IQNPSNVDHYSKLLFPLIFMLANVFYWAYYMY 439
>UniRef50_Q9Y0I3 Cluster: Ionotropic GABA receptor subunit
UNC-49B.3; n=11; Eumetazoa|Rep: Ionotropic GABA receptor
subunit UNC-49B.3 - Caenorhabditis elegans
Length = 506
Score = 169 bits (411), Expect = 2e-40
Identities = 93/254 (36%), Positives = 139/254 (54%), Gaps = 15/254 (5%)
Query: 146 ITSVLENLLKN--YENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWR 203
++SVL+ L Y+ P +G+ P V I + S+ VSE+DMD+++D Y RQ W+
Sbjct: 34 LSSVLDRLTNRTTYDKRLRPRYGEK-PVDVGITIHVSSISAVSEVDMDFTLDFYMRQTWQ 92
Query: 204 DTRLSF----LG---PIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQH 256
D RL+F LG I SL++ + L+R+W+PDT+F N K S+ H T N LRI
Sbjct: 93 DPRLAFGSLDLGLSKEIDSLTVGVDYLDRLWKPDTFFPNEKKSFFHLATTHNSFLRIEGD 152
Query: 257 GDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMT 316
G + S RLT+ A CPM+L+ FPMD Q C L + SY Y + + Y W ++ + +
Sbjct: 153 GTVYTSQRLTVTATCPMDLKLFPMDSQHCKLEIESYGYETKDIDYYWGKKRTDLEITAVK 212
Query: 317 LSQFDLISF-PYRNFTFTRR----EGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSW 371
F L F P F T + G + L + L R+ G++ + + +P ILIV +SW
Sbjct: 213 FDTFQLPQFQPTLYFVNTTKAETSSGKYVRLALEVILVRNMGFYTMNIVIPSILIVTISW 272
Query: 372 VSFWIHREVGSGEI 385
VSFW++RE +
Sbjct: 273 VSFWLNREASPARV 286
>UniRef50_UPI0000D9B066 Cluster: PREDICTED: gamma-aminobutyric acid
A receptor, alpha 2 isoform 2; n=2; Euteleostomi|Rep:
PREDICTED: gamma-aminobutyric acid A receptor, alpha 2
isoform 2 - Macaca mulatta
Length = 403
Score = 169 bits (410), Expect = 2e-40
Identities = 77/149 (51%), Positives = 101/149 (67%), Gaps = 1/149 (0%)
Query: 147 TSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTR 206
T +L+ LL Y+N P G T V TNI + S GPVS+ DM+Y++D +FRQ W+D R
Sbjct: 43 TRILDRLLDGYDNRLRPGLGDSI-TEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDER 101
Query: 207 LSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLT 266
L F GP+ L L+ M +IW PDT+F+NGK S H +T+PNKLLRI G +LY+MRLT
Sbjct: 102 LKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLT 161
Query: 267 IKAKCPMELRNFPMDRQSCPLILGSYAYS 295
++A+CPM L +FPMD SCPL GS Y+
Sbjct: 162 VQAECPMHLEDFPMDAHSCPLKFGSCEYT 190
Score = 59.7 bits (138), Expect = 2e-07
Identities = 23/42 (54%), Positives = 34/42 (80%)
Query: 338 DFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
+++V+ F+LKR GYF+IQ Y+PCI+ V+LS VSFW++RE
Sbjct: 188 EYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 229
Score = 41.9 bits (94), Expect = 0.041
Identities = 17/43 (39%), Positives = 25/43 (58%)
Query: 478 RRQRQREAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
++ + A ++ NSVS IDR +R++FP F NL YW Y
Sbjct: 350 KKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATY 392
>UniRef50_A7RS31 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 303
Score = 167 bits (406), Expect = 7e-40
Identities = 78/214 (36%), Positives = 125/214 (58%), Gaps = 6/214 (2%)
Query: 170 PTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF---LG--PIRSLSLSIKMLE 224
P +V T + + S+ E DM+++ + YFRQ W D RL+F +G + ++L + +
Sbjct: 1 PVLVTTELNLVSISQFREADMEFTAEMYFRQAWHDPRLAFGVTMGNSTVPVITLYGDLSD 60
Query: 225 RIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQS 284
+W+PDTYF N +H +T+ NK +R+ G ++ S+R+T+ C M+ R FPMD+Q+
Sbjct: 61 SLWQPDTYFENEVQGKIHELTIKNKYMRVYSDGRVMTSLRVTLSCSCAMDFRKFPMDKQN 120
Query: 285 CPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFSVLQV 344
C + SY Y+ +VYQW + + V + ++QF L N T GDFS L +
Sbjct: 121 CGISFASYGYTTADIVYQWAD-ERVTWAHDQEIAQFVLEKIETENLTRRYITGDFSALGI 179
Query: 345 SFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHR 378
L R G++L +VYVP +LIV+LSW+SF++ R
Sbjct: 180 RLRLNRRLGHYLTRVYVPAVLIVMLSWLSFYLDR 213
>UniRef50_Q4SKT9 Cluster: Chromosome undetermined SCAF14565, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF14565, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 502
Score = 165 bits (402), Expect = 2e-39
Identities = 79/208 (37%), Positives = 127/208 (61%), Gaps = 2/208 (0%)
Query: 173 VQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPI-RSLSLSIKMLERIWRPDT 231
V ++ + S+ +SE++MD++M Y R YW+D RL+F +S + +++++IW PD
Sbjct: 86 VGIDVQVESIDSISEVNMDFTMTLYLRHYWKDERLAFPSQTNQSRTFDSRLVKKIWVPDV 145
Query: 232 YFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGS 291
+F + K S++H T+ N +LR+ G+IL+S+R+T+ A M+ FP+D Q+C L L S
Sbjct: 146 FFVHSKRSFIHDTTMENIMLRVYPDGNILFSVRVTVTALRSMDFTIFPLDTQNCSLELES 205
Query: 292 YAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRN-FTFTRREGDFSVLQVSFNLKR 350
YAY+ L+ W+N + LSQF + F + F G ++ L +SF L+R
Sbjct: 206 YAYNENDLMLYWKNGNDSLRTDEIVLSQFFIEQFQASSGLAFYSSTGWYNRLFISFLLRR 265
Query: 351 HTGYFLIQVYVPCILIVVLSWVSFWIHR 378
H +F++Q Y P +L+VVLSWVSFWI R
Sbjct: 266 HIFFFMLQTYFPTMLMVVLSWVSFWIDR 293
Score = 35.1 bits (77), Expect = 4.8
Identities = 17/46 (36%), Positives = 25/46 (54%)
Query: 476 RYRRQRQREAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIYA 521
R RRQR +++ ID +RV+FP S+ L N YW +Y+
Sbjct: 457 RLRRQRSVRENVDLLVSNSYLIDSYSRVVFPLSYLLFNTIYWGLYS 502
>UniRef50_A7SFV7 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 428
Score = 164 bits (398), Expect = 6e-39
Identities = 84/250 (33%), Positives = 141/250 (56%), Gaps = 8/250 (3%)
Query: 144 KNITSVLENLLK--NYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQY 201
+ +T +L+ LL NY+N P + G P VV+ I S+ + ++MD+++D + RQ
Sbjct: 31 ERMTQILDTLLDKVNYDNRVRPFYN-GKPVVVKVGYWILSVDSIDVVNMDFTVDLFLRQE 89
Query: 202 WRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILY 261
W D RL G ++ L +++++IW PD+YF N K + +H +T PN++ I+ G + Y
Sbjct: 90 WVDPRLDH-GLNETIYLGHRVMQKIWTPDSYFLNAKTAKMHHVTTPNQMTLIAPMGVVKY 148
Query: 262 SMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQN--SQSVNFVPG--MTL 317
+ R+T+KA C ++LR+FPMD+Q+CPL+L SY Y +VY W+ + + FVP +
Sbjct: 149 NTRVTVKAACTIDLRSFPMDQQNCPLVLESYGYDRSHIVYHWEGNATDGLPFVPNRMRIM 208
Query: 318 SQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIH 377
Q+ L+ G+FS + F+++R YFL VY +IV +SW+ F I
Sbjct: 209 PQYSLVRLTLSREWHQYIIGNFSAVVAVFSIERSYTYFLTHVYGTSCVIVFISWMGFVIP 268
Query: 378 REVGSGEIVI 387
+ + I +
Sbjct: 269 PDQTAARIAV 278
>UniRef50_Q4S0E0 Cluster: Chromosome 2 SCAF14781, whole genome
shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 2
SCAF14781, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 525
Score = 163 bits (397), Expect = 8e-39
Identities = 91/251 (36%), Positives = 136/251 (54%), Gaps = 31/251 (12%)
Query: 168 GYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLG-PIRSLSLSIKMLERI 226
G P V NI I S G ++E MDY ++ + RQ W D RL++ P SL L ML+ I
Sbjct: 112 GPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSKYPDPSLDLDPSMLDSI 171
Query: 227 WRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFP------- 279
W+PD +F N K + H +T NKLLRI ++G++LYS+RLT+ CPM+L+NFP
Sbjct: 172 WKPDLFFANEKGANFHDVTTDNKLLRIFKNGNVLYSIRLTLILSCPMDLKNFPMDVQTCT 231
Query: 280 MDRQSCPLILGSY----------------------AYSNQQLVYQWQNSQSVNFVPGMTL 317
M +SC S+ Y+ L+++W + +V G+TL
Sbjct: 232 MQLESCECCFLSFPRLSQRPRALILTHLSRSSLPVGYTMNDLIFEWLENGAVQVSDGLTL 291
Query: 318 SQFDLISFPYRNF-TFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
QF + + T G F+ ++V F+L+R GY+LIQ+Y+P +LIV+LSWVSFWI
Sbjct: 292 PQFIMRDEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWI 351
Query: 377 HREVGSGEIVI 387
+ + + +
Sbjct: 352 NMDAAPARVAL 362
Score = 34.3 bits (75), Expect = 8.3
Identities = 12/40 (30%), Positives = 21/40 (52%)
Query: 481 RQREAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
R + + ++ ID +R FP +F + N+FYW+ Y
Sbjct: 475 RDMDTMRKKFVDRAKRIDTISRAAFPLAFLIFNVFYWVTY 514
>UniRef50_O46123 Cluster: GBR-2A protein precursor; n=3;
Chromadorea|Rep: GBR-2A protein precursor - Haemonchus
contortus (Barber pole worm)
Length = 421
Score = 162 bits (393), Expect = 2e-38
Identities = 80/225 (35%), Positives = 129/225 (57%), Gaps = 13/225 (5%)
Query: 168 GYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF---------LGPIRSLSL 218
G P +V NI +RS+ + +++M+YS FR+ W D RL++ + P L+
Sbjct: 64 GGPVLVTVNIYLRSISKIDDVNMEYSAQFTFREEWVDARLAYGRFEDESTEVPPFVVLAT 123
Query: 219 S--IKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELR 276
S ++IW PDT+F N K + H I PN L+RI + G ILYS+RL++ CPM L
Sbjct: 124 SENADQSQQIWMPDTFFQNEKVARRHLIDKPNVLIRIHKDGSILYSVRLSLVLSCPMSLE 183
Query: 277 NFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGM--TLSQFDLISFPYRNFTFTR 334
+P+DRQ+C + L SY Y+ Q + Y+W+ V G+ +L F+L + T
Sbjct: 184 FYPLDRQNCLIDLASYGYTTQDIKYEWKEQNPVQQKDGLRQSLPSFELQDVVTKYCTSKT 243
Query: 335 REGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
G++S L+ L+R Y+L+Q+Y+P ++V++SWVSFW+ ++
Sbjct: 244 NTGEYSCLRTQMVLRREFSYYLLQLYIPSFMLVIVSWVSFWLDKD 288
>UniRef50_A7S6R3 Cluster: Predicted protein; n=3; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 409
Score = 160 bits (389), Expect = 7e-38
Identities = 80/234 (34%), Positives = 132/234 (56%), Gaps = 8/234 (3%)
Query: 145 NITSVLENLLK--NYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYW 202
N T + E +L NY+ P GK P V +I +++ + E +M+++ + RQ W
Sbjct: 41 NATRLQERMLSSSNYDRKARPNAGKE-PLDVYLSIGVQAFTSIKETNMEFTTSLFLRQEW 99
Query: 203 RDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYS 262
D RL+ G ++SL + +IWRPDTY N +H V N+L IS++GD+ +S
Sbjct: 100 TDIRLAH-GLDGTISLGGVEVNQIWRPDTYINNNNDYELH---VENQLALISKYGDVYFS 155
Query: 263 MRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDL 322
R+ ++A C M L+NFPMD Q C L+ S+AY+N + + W+ + + LS+FD+
Sbjct: 156 ARMLVRASCQMYLQNFPMDVQKCSLVFESFAYTNDHVAFHWKGRNPIT-IFNKELSEFDM 214
Query: 323 ISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
+ T G + L+V+F +R G++LI YVPC+++V++SW+ FW+
Sbjct: 215 EQWLIEEVDMTYVAGKYRNLKVTFIFRRRLGFYLINFYVPCVVMVIMSWIVFWM 268
>UniRef50_A7SVS1 Cluster: Predicted protein; n=5; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 318
Score = 159 bits (385), Expect = 2e-37
Identities = 80/243 (32%), Positives = 140/243 (57%), Gaps = 4/243 (1%)
Query: 145 NITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 204
NI+ +L+++ K Y+ P +G +Q ++LI S G +SE +M++++D Y Q+W++
Sbjct: 1 NISKLLDDVFKRYDKRIRPYYGIK-AVDIQLDMLILSFGELSETNMEFTVDMYLGQFWKE 59
Query: 205 TRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRIS-QHGDILYSM 263
RL+F G R + LS E++W PDT+F N + VH + NK + I+ G ++ S
Sbjct: 60 PRLAF-GIKREIILSGVASEKLWVPDTFFVNSIDTKVHALLFSNKKVWINLTDGSVMLSA 118
Query: 264 RLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNF-VPGMTLSQFDL 322
RLT + C ++LRN+PMD Q+C L S++Y + L Y W++ + + ++QFD+
Sbjct: 119 RLTTRNSCKVDLRNYPMDEQTCHLPFESFSYEQKDLNYTWRSKVGSDIAIYDKEMAQFDI 178
Query: 323 ISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGS 382
I+ FS L + + +R + Y++ Q+Y+PC +V+LSW++FWI + GS
Sbjct: 179 IAAKRFLKHPVYHSPMFSGLTATMSFRRRSLYYIFQMYIPCTCVVILSWIAFWIDPKEGS 238
Query: 383 GEI 385
+
Sbjct: 239 ERV 241
>UniRef50_A7SNP9 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 469
Score = 159 bits (385), Expect = 2e-37
Identities = 83/248 (33%), Positives = 136/248 (54%), Gaps = 8/248 (3%)
Query: 146 ITSVLENLLKN--YENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWR 203
+T L+ L K Y+ P + G P +V T + S+ ++ DM + MD + RQ W
Sbjct: 49 MTDTLDELFKRPRYDPRLRPQYNDG-PVLVTTGFWVLSIDSINVQDMAFGMDIFLRQNWV 107
Query: 204 DTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSM 263
D RL G ++LSLS ++ IW PD+YF N K + H +T N ++ I G + Y+
Sbjct: 108 DNRLDH-GLNQTLSLSNAVMSNIWLPDSYFKNAKQANFHEVTSKNLMITIGPKGKVHYNT 166
Query: 264 RLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQ--SVNFVPG--MTLSQ 319
R+T+KA C M+LR +P D Q CPLI+ SY YS + ++Y+W+ + ++FVP L Q
Sbjct: 167 RVTLKASCSMDLRLYPFDIQHCPLIMESYGYSVEHIMYKWEKGEGDGMSFVPRDVKLLPQ 226
Query: 320 FDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
F+L + G++S + +F +R +++I +Y P LIV++SW+SF + R+
Sbjct: 227 FNLTKLELSSRNTQYVIGNWSGVMATFTFERTYSFYVIHIYGPSALIVLISWISFLLPRD 286
Query: 380 VGSGEIVI 387
+ +
Sbjct: 287 QSPARVTL 294
>UniRef50_A7S448 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 366
Score = 158 bits (384), Expect = 3e-37
Identities = 79/194 (40%), Positives = 112/194 (57%), Gaps = 5/194 (2%)
Query: 188 LDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVP 247
+ DYS+D +FRQ+WRD RL+ + +++ + W PDTYF N K S H +T
Sbjct: 1 IHQDYSLDIFFRQWWRDERLAH-DVNKVFNMAANPGQYFWTPDTYFVNVKSSKFHHVTRE 59
Query: 248 NKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQN-- 305
N +I G I YS R+T+ A C M+LR FPMD Q C L + SYAY+ + ++Y W N
Sbjct: 60 NMRTKIWPDGLIYYSSRITLTASCEMDLRFFPMDTQDCVLKIESYAYTVEDVIYNWNNRG 119
Query: 306 SQSVNFVPGMTLSQFDLISFPYRN-FTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCI 364
+ + G ++QFD+ + TF+ G F L+VSF KR T YF++Q YVP
Sbjct: 120 TTPIEIFAG-EMAQFDMTEMTMQTMITFSLLTGSFDSLRVSFRFKRRTSYFIVQHYVPSA 178
Query: 365 LIVVLSWVSFWIHR 378
IV LSW+ FWI++
Sbjct: 179 FIVFLSWLGFWINK 192
>UniRef50_Q2WF65 Cluster: Gaba/glycine receptor family (See gbr)
protein 2, isoform a; n=3; Caenorhabditis|Rep:
Gaba/glycine receptor family (See gbr) protein 2,
isoform a - Caenorhabditis elegans
Length = 546
Score = 157 bits (380), Expect = 9e-37
Identities = 83/252 (32%), Positives = 130/252 (51%), Gaps = 5/252 (1%)
Query: 133 QNKRSINDAVSKNITSVLENLLKN----YENSQLPT-HGKGYPTVVQTNILIRSMGPVSE 187
+N + + S+ + L+NLL Y+N P H K TVV+ + I M
Sbjct: 13 RNSPKVEASRSEPVPIYLDNLLNAGRQVYDNQSPPVQHDKEEVTVVELAMYIEGMSSFRT 72
Query: 188 LDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVP 247
MD+ +D YF+Q+WRD RL+ R L +L ++W+PD YF N + + H +T P
Sbjct: 73 QTMDFQLDVYFQQFWRDPRLAHNETRRVLVKDKAVLHKMWKPDVYFANARIAEFHEVTQP 132
Query: 248 NKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQ 307
N L+ I G ILY R+++ C + L +P+D Q C L + SYAY+ +QLV +W+ +
Sbjct: 133 NFLVWIQPDGSILYDTRISMVVVCTLNLEKWPLDSQRCHLRILSYAYTTEQLVIKWKEDE 192
Query: 308 SVNFVPGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIV 367
+ P + +S ++ G +S + F +KR + ++Q YVP LIV
Sbjct: 193 PITRNPNIAMSDMHIVDLYPGLCDGNYSTGTWSCVTAEFFVKREITHHVMQSYVPTTLIV 252
Query: 368 VLSWVSFWIHRE 379
V+SW SFW+ E
Sbjct: 253 VISWFSFWLDVE 264
Score = 34.3 bits (75), Expect = 8.3
Identities = 12/31 (38%), Positives = 19/31 (61%)
Query: 492 NSVSHIDRAARVLFPASFALLNLFYWMIYAF 522
N ID+ +R +FP +F + NL YW+ Y +
Sbjct: 513 NRAKKIDQTSRWIFPLTFIIFNLTYWIYYLY 543
>UniRef50_A7S2G2 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 270
Score = 157 bits (380), Expect = 9e-37
Identities = 75/214 (35%), Positives = 118/214 (55%), Gaps = 5/214 (2%)
Query: 168 GYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF-LGPIRSLS---LSIKML 223
G P + N+ I S+ V E MDY+M FRQ WRD RL++ + R + ++
Sbjct: 1 GQPVNITVNMRINSVFDVREEAMDYTMRFAFRQKWRDPRLTYNISLTRGQGHPYIQLETA 60
Query: 224 ERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQ 283
+ IW PDT+F N + SY+H +T N +R+ G I S ++T+ A+C M+LR FPMD Q
Sbjct: 61 DLIWYPDTFFMNARKSYIHDVTKKNLGIRLFPDGSIYMSQKITVTAECQMDLRKFPMDTQ 120
Query: 284 SCPLILGSYAYSNQQLVYQWQNSQS-VNFVPGMTLSQFDLISFPYRNFTFTRREGDFSVL 342
C L S+ ++ ++V +W+ + V M L FD++ + + G F+ L
Sbjct: 121 VCVLQFESFFHTAAEIVLRWEEGDTPVAISKDMNLPHFDIVGLETKQIYNVYKSGKFNSL 180
Query: 343 QVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
+V +R GY+LIQ Y+PC+ + LSW+ FW+
Sbjct: 181 EVHITFRRRLGYYLIQTYLPCVFLCFLSWMPFWM 214
>UniRef50_A7RZG9 Cluster: Predicted protein; n=3; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 405
Score = 155 bits (376), Expect = 3e-36
Identities = 74/243 (30%), Positives = 138/243 (56%), Gaps = 5/243 (2%)
Query: 135 KRSINDAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSM 194
++S+ +A +N++ + N+++ + + P G G +V + S G + E +M+YS+
Sbjct: 32 RKSMEEA--RNLSLFINNVIRRHPRNVRPNAG-GEKVMVDIEFKVISFGEIKEANMEYSL 88
Query: 195 DCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRIS 254
D +FRQ+W D+R + + +++ E W PDTYF+N K + H +T N + I+
Sbjct: 89 DIFFRQWWYDSRFAHNYSM-PFTMAADPTELFWTPDTYFWNVKSANYHRVTRENMRVMIN 147
Query: 255 QHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNF-VP 313
G I +S R+T+ +C M+L +P+D Q CPL + SYA++ + Y+W+ ++ +
Sbjct: 148 PDGKIYFSARITLTCQCEMDLHLYPLDTQECPLRIESYAHTVADVDYRWKGGETQGVEIV 207
Query: 314 GMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVS 373
++QFDL+ T +G F+ L+ +F +R ++L +YVP +++VVLSW +
Sbjct: 208 SEEMAQFDLLGVRTDTKKSTNSKGAFASLKATFRFRRRMDFYLSSIYVPEVILVVLSWTT 267
Query: 374 FWI 376
F+I
Sbjct: 268 FFI 270
>UniRef50_Q9VDU9 Cluster: CG7411-PA; n=12; Endopterygota|Rep:
CG7411-PA - Drosophila melanogaster (Fruit fly)
Length = 485
Score = 152 bits (369), Expect = 2e-35
Identities = 76/244 (31%), Positives = 125/244 (51%), Gaps = 3/244 (1%)
Query: 146 ITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDT 205
IT +L +K Y+ + P +G PT+V ++ + + + E M Y D +F Q W+D
Sbjct: 29 ITDILPEDIKRYDKMR-PPKKEGQPTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDH 87
Query: 206 RLSFLGPIRS--LSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSM 263
RL + L + L+ +WRPD++F N K T+T+PN + + + ILY +
Sbjct: 88 RLRLPENMTQEYRLLEVDWLKNMWRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMV 147
Query: 264 RLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLI 323
+LT+K C M +P D Q C L + S +++ L++QW + + + L Q LI
Sbjct: 148 KLTLKLSCIMNFAIYPHDTQECKLQMESLSHTTDDLIFQWDPTTPLVVDENIELPQVALI 207
Query: 324 SFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSG 383
+ T G+F+ L+V F LKR Y++ Y+P +IV++SWVSFWI E
Sbjct: 208 RNETADCTQVYSTGNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPA 267
Query: 384 EIVI 387
+ +
Sbjct: 268 RVTL 271
Score = 37.9 bits (84), Expect = 0.68
Identities = 15/25 (60%), Positives = 20/25 (80%)
Query: 496 HIDRAARVLFPASFALLNLFYWMIY 520
+IDR++RVLFPA FA LN YW ++
Sbjct: 457 YIDRSSRVLFPALFASLNGIYWCVF 481
>UniRef50_Q17328 Cluster: Glutamate-gated chloride channel subunit
beta precursor; n=8; Chromadorea|Rep: Glutamate-gated
chloride channel subunit beta precursor - Caenorhabditis
elegans
Length = 434
Score = 151 bits (367), Expect = 3e-35
Identities = 85/252 (33%), Positives = 137/252 (54%), Gaps = 16/252 (6%)
Query: 149 VLENLLKNYENSQLPTHGKGYP---TVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDT 205
+L LLKNY+ P V+ NI+IR + + ++M+YS+ FR+ W D
Sbjct: 32 ILNALLKNYDMRVRPPPANSSTEGAVNVRVNIMIRMLSKIDVVNMEYSIQLTFREQWIDP 91
Query: 206 RLSF--LGPIRSLS-LSIKMLER-IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILY 261
RL++ LG + L++ +++ +W PDT+F K ++ H I + N LRI G ILY
Sbjct: 92 RLAYENLGFYNPPAFLTVPHVKKSLWIPDTFFPTEKAAHRHLIDMENMFLRIYPDGKILY 151
Query: 262 SMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFD 321
S R+++ + CPM L+ +P+D QSC L SYA++ ++Y+W S V PG+ D
Sbjct: 152 SSRISLTSSCPMRLQLYPLDYQSCNFDLVSYAHTMNDIMYEWDPSTPVQLKPGV---GSD 208
Query: 322 LISFPYRNFTFT------RREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFW 375
L +F +N+T G + L++ KR Y+L+Q+Y P +IV++SWVSFW
Sbjct: 209 LPNFILKNYTTNADCTSHTNTGSYGCLRMQLLFKRQFSYYLVQLYAPTTMIVIVSWVSFW 268
Query: 376 IHREVGSGEIVI 387
I +G + +
Sbjct: 269 IDLHSTAGRVAL 280
>UniRef50_A7SH22 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 239
Score = 149 bits (361), Expect = 2e-34
Identities = 74/219 (33%), Positives = 122/219 (55%), Gaps = 4/219 (1%)
Query: 170 PTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRP 229
PT V+ + + S G + E ++++S+ YFRQ WRD RL+ +S+ L + +W P
Sbjct: 1 PTDVKLDFYVESFGNIEEANLEFSVFMYFRQMWRDPRLADRVN-QSVVLQRDQISYLWFP 59
Query: 230 DTYFYNGKHS-YVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLI 288
DTY N K S + T + L + G I YS I A C M+LR+FPMD Q+C L+
Sbjct: 60 DTYCSNAKRSDLMSPDTEIHSSLTLEPDGSIFYSRSAHIVASCEMDLRDFPMDTQTCNLV 119
Query: 289 LGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNL 348
GSY Y++ + W++++ + + ++QF L + T +G++++L SF +
Sbjct: 120 FGSYGYTDNDIKLSWKSTKIL--IANKEMAQFSLGDCVLSSKTMEYVQGNYTLLSASFPM 177
Query: 349 KRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVI 387
R GY+ IQ+YVPC +V+LSW+ FW++ E + +
Sbjct: 178 HRRIGYYAIQMYVPCTFLVMLSWIVFWMNPEETGNRLTV 216
>UniRef50_Q08861 Cluster: Gamma-aminobutyric acid-grated
chloride-ion channel/receptor, zeta subunit precursor;
n=1; Lymnaea stagnalis|Rep: Gamma-aminobutyric
acid-grated chloride-ion channel/receptor, zeta subunit
precursor - Lymnaea stagnalis (Great pond snail)
Length = 437
Score = 147 bits (356), Expect = 7e-34
Identities = 79/258 (30%), Positives = 144/258 (55%), Gaps = 24/258 (9%)
Query: 143 SKNITSVLENLLKNYENSQL--PTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQ 200
S+ +T+++ Y++ + P++ K P +Q + + S+ V+E MD+++
Sbjct: 28 SEILTNIVRLAHDTYDDLKTAPPSYDKLEPARIQVLLYVSSIDAVNEASMDFTVGILLHL 87
Query: 201 YWRDTRLS-------FL-GPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLR 252
W DTR+ FL ++SL + ++++W PD +F N K H I N+++R
Sbjct: 88 RWTDTRIYHDKAHNLFLQSKLQSLDFDSENIKKVWVPDIFFPNEKKGSFHDIMTQNQMMR 147
Query: 253 ISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQN---SQSV 309
+ Q G ILY RL++ CPM+L N+P D+Q+C +++ S+ YS+Q LV W N + +
Sbjct: 148 LYQGGTILYISRLSMTLSCPMDLINYPFDKQTCHILIMSFGYSDQDLVLDWMNLTTADDL 207
Query: 310 NFVPG---------MTLSQFDLISF--PYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQ 358
P + L QF++ S + N + ++ G+ S +Q F+L R+ G++++Q
Sbjct: 208 TMNPDGKAIVVDSEVLLPQFEVKSVIPSFCNRRYHQKAGNHSCIQAEFHLARNIGFYIVQ 267
Query: 359 VYVPCILIVVLSWVSFWI 376
+Y+P +LIV+LSW+SFW+
Sbjct: 268 MYIPSMLIVMLSWISFWL 285
Score = 36.7 bits (81), Expect = 1.6
Identities = 18/71 (25%), Positives = 34/71 (47%), Gaps = 1/71 (1%)
Query: 450 TMERTTQTETRVPRWRQLLYCLAGDDRYRRQRQREAGSRGHINSVSHIDRAARVLFPASF 509
T+ + T E ++ L G Q+++ RG + ++ ++D ARV+FP F
Sbjct: 364 TLPKDTDKEDGPLNMAEMTVPLDGFHEAEAQKKKRFNKRGIVYAI-YVDMTARVVFPICF 422
Query: 510 ALLNLFYWMIY 520
+ + YW+ Y
Sbjct: 423 IIFIMSYWLYY 433
>UniRef50_A7SAS4 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 293
Score = 147 bits (356), Expect = 7e-34
Identities = 79/243 (32%), Positives = 129/243 (53%), Gaps = 4/243 (1%)
Query: 146 ITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDT 205
I++ ++ L Y+N P G G P + + + S V E DM++S+D +F+Q WRD
Sbjct: 5 ISNAIDGLFVGYDNRLRPYFG-GPPLNISVYMSVVSFSTVYEKDMEFSLDVFFKQAWRDP 63
Query: 206 RLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRL 265
RL + + L E+ W PDT+F N K + H + N + ++ GDI S RL
Sbjct: 64 RLRHSAKMPFI-LPGSQKEKFWIPDTFFLNVKTARFHQVPAANTRIVVTPDGDIELSERL 122
Query: 266 TIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDL-IS 324
T+ A C M+LR +P+D+Q+C L + SY++ + Y+W+ + + + G +++F+L S
Sbjct: 123 TVSASCRMDLRMYPLDQQTCVLEILSYSFDINDIDYRWKAKEDLIILDG-EMNEFELKDS 181
Query: 325 FPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGE 384
R G ++ L F +R Y IQ+Y P LIVVLSW+SFWI ++
Sbjct: 182 RGERKQKSRSCTGTYTHLVAKFVFRRRLAYSFIQIYSPTFLIVVLSWLSFWISKDAVPAR 241
Query: 385 IVI 387
+ +
Sbjct: 242 VAL 244
>UniRef50_A7SDF0 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 349
Score = 146 bits (354), Expect = 1e-33
Identities = 74/185 (40%), Positives = 109/185 (58%), Gaps = 4/185 (2%)
Query: 197 YFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVP-NKLLRISQ 255
YFRQ+W+D RL+ +S+ L + ++WRPD + YN + S + N ++ I
Sbjct: 1 YFRQFWKDERLANRLN-KSVVLKGDEITKMWRPDPFCYNARESSLTASDDDINSMMTIHP 59
Query: 256 HGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGM 315
+GD++YS I A+C M+L +FPMD Q C L LGSY+YS + +VY+WQ+ V V
Sbjct: 60 NGDVVYSRMTIITAECEMKLHDFPMDEQQCHLKLGSYSYSTKNIVYRWQSPLGVT-VRNK 118
Query: 316 TLSQFDLISFPYRNF-TFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSF 374
L+QF + G++S+LQV F KR GYFLIQVY P I +V+LSW+ F
Sbjct: 119 NLAQFIFTYLELSEYEEIYGMMGNYSILQVDFAFKRRLGYFLIQVYAPDIFVVLLSWIVF 178
Query: 375 WIHRE 379
W+ ++
Sbjct: 179 WMDKD 183
Score = 35.1 bits (77), Expect = 4.8
Identities = 12/26 (46%), Positives = 18/26 (69%)
Query: 495 SHIDRAARVLFPASFALLNLFYWMIY 520
S +D+ AR++FP F + N+ YW IY
Sbjct: 320 SDVDKFARIVFPMVFIVFNILYWCIY 345
>UniRef50_A7RTF6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 291
Score = 146 bits (354), Expect = 1e-33
Identities = 76/237 (32%), Positives = 128/237 (54%), Gaps = 9/237 (3%)
Query: 145 NITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 204
NIT +L +L+ Y++ P G G P V+ N+ S P++E M+Y+ YFRQYW+D
Sbjct: 1 NITLLLSEILRGYDSLLRPGLG-GKPCRVKVNLYFMSFAPINEPQMEYTPTFYFRQYWQD 59
Query: 205 TRLSFLGPIRSLSLSIK--MLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYS 262
RL+F IR+ ++ + ++IW PDT+F + V + + +L IS +G +
Sbjct: 60 PRLAFGDSIRAEAIRPRGDFTKKIWTPDTFFIDDVTDNVRRV---DSMLEISSNGSFNTN 116
Query: 263 --MRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW-QNSQSVNFVPGMTLSQ 319
R I++ CPM FP D Q C S++Y+++ LVY+W +N ++ F + ++
Sbjct: 117 RFFRWRIRSFCPMTFTRFPFDVQRCSFTFSSFSYNDKDLVYEWMKNPPALEFSSQLRMAH 176
Query: 320 FDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
+DLI + + G ++ L F KR ++++ ++P IV+LSWV FWI
Sbjct: 177 YDLIEWSTESKLDEFVTGKYASLTAKFVFKRRVRFYILSAFIPAAFIVILSWVGFWI 233
>UniRef50_Q9VGI0 Cluster: CG14723-PA, isoform A; n=12;
Endopterygota|Rep: CG14723-PA, isoform A - Drosophila
melanogaster (Fruit fly)
Length = 426
Score = 146 bits (353), Expect = 2e-33
Identities = 76/239 (31%), Positives = 123/239 (51%), Gaps = 3/239 (1%)
Query: 143 SKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYW 202
S ++ +L K Y+ ++ P G PTVV ++ + S+ ++E M Y D + Q W
Sbjct: 53 SLSLPDILPIPSKTYDKNRAPKL-LGQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSW 111
Query: 203 RDTRLSFLGPIRSLS--LSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDIL 260
RD RL + L + L IWRPD +F N K H +++PN L + +L
Sbjct: 112 RDPRLRLPENMSEQYRILDVDWLHSIWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKTLL 171
Query: 261 YSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQF 320
Y +LT+ C M+ ++P D Q C +++ S +++ + LV+ W + + + L Q
Sbjct: 172 YMSKLTLVLSCAMKFESYPHDTQICSMMIESLSHTVEDLVFIWNMTDPLVVNTEIELPQL 231
Query: 321 DLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
D+ + + T G+F+ L + FNL+R GY L Y+P LIVV+SW+SFWI E
Sbjct: 232 DISNNYTTDCTIEYSTGNFTCLAIVFNLRRRLGYHLFHTYIPSALIVVMSWISFWIKPE 290
Score = 34.3 bits (75), Expect = 8.3
Identities = 14/39 (35%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Query: 482 QREAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
Q + GH ++ +ID+ +R FP SF +LN+ YW +
Sbjct: 388 QYDTFCHGHATAI-YIDKFSRFFFPFSFFILNIVYWTTF 425
>UniRef50_Q9GQ00 Cluster: Serotonin-gated chloride channel; n=4;
Caenorhabditis|Rep: Serotonin-gated chloride channel -
Caenorhabditis elegans
Length = 489
Score = 146 bits (353), Expect = 2e-33
Identities = 71/229 (31%), Positives = 128/229 (55%), Gaps = 7/229 (3%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
++ ++ NY LP V I ++ MG ++E+ D+ +D F Q W D+ LS
Sbjct: 37 IMNTIMSNY-TKMLPDAEDSVQ--VNIEIHVQDMGSLNEISSDFEIDILFTQLWHDSALS 93
Query: 209 FLG-PI--RSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRL 265
F P R++++ ++L +IW P+T N K + VH N ++ + ++G + + RL
Sbjct: 94 FAHLPACKRNITMETRLLPKIWSPNTCMINSKRTTVHASPSENVMVILYENGTVWINHRL 153
Query: 266 TIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISF 325
++K+ C ++LR FP D Q+C LI SY+++++++ W ++V + + L FD++ +
Sbjct: 154 SVKSPCNLDLRQFPFDTQTCILIFESYSHNSEEVELHWM-EEAVTLMKPIQLPDFDMVHY 212
Query: 326 PYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSF 374
+ T G + LQV+F KR G+++IQ YVP L +++SWVSF
Sbjct: 213 STKKETLLYPNGYWDQLQVTFTFKRRYGFYIIQAYVPTYLTIIVSWVSF 261
>UniRef50_A7RTF8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 262
Score = 146 bits (353), Expect = 2e-33
Identities = 76/191 (39%), Positives = 114/191 (59%), Gaps = 13/191 (6%)
Query: 197 YFRQYWRDTRLSFLGPI---RSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRI 253
+ RQ W D RL++ G + R+L+L ++++IW+PDTY N K S T+ LL I
Sbjct: 6 FLRQLWTDPRLAY-GHVYKKRNLTLGGDIMKQIWKPDTYINNEKSS---TVPENQFLLTI 61
Query: 254 SQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNS------Q 307
G ++YS R+T+ A C M LRN+PMD QSC + SY +N L+ W+
Sbjct: 62 DPEGRVVYSQRMTVVASCMMYLRNYPMDTQSCSISFESYGMNNDDLLLSWKADPGDKYKN 121
Query: 308 SVNFVPGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIV 367
+V +T+SQF L + TFT G F++L+++F+++R Y+++Q Y+P ILIV
Sbjct: 122 AVIISDNLTMSQFALDEYHASKETFTYPTGTFTLLKLTFSIRRKKFYYVVQTYIPTILIV 181
Query: 368 VLSWVSFWIHR 378
+LSWVSFWI R
Sbjct: 182 ILSWVSFWIPR 192
>UniRef50_Q95QT7 Cluster: Glutamate-gated chloride channel protein
4; n=2; Caenorhabditis|Rep: Glutamate-gated chloride
channel protein 4 - Caenorhabditis elegans
Length = 500
Score = 141 bits (342), Expect = 4e-32
Identities = 78/239 (32%), Positives = 124/239 (51%), Gaps = 14/239 (5%)
Query: 152 NLLKNYENSQLPTHGKGY-----PTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTR 206
+LL++Y+ + P+ Y +V T++ IRS+ VSE +M++ FRQ W D R
Sbjct: 50 DLLQDYDAAVRPSGRTPYNDTRGAVMVTTSLNIRSISAVSEKNMEFVAQFRFRQEWYDDR 109
Query: 207 LSFLGPIRSLSLSIKMLERI--------WRPDTYFYNGKHSYVHTITVPNKLLRISQHGD 258
L F+ LS + E I W PDT+F N K+ + H + N+ L+I G
Sbjct: 110 LRFIEHQGLLSSDYRNFEFIHVARDQSLWIPDTFFQNEKNGWYHMLNQENRFLKIRSDGK 169
Query: 259 ILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQ-NSQSVNFVPGMTL 317
++Y RLT+ C M L +PMD Q+C + SYAY+ + Y W + ++ L
Sbjct: 170 LIYDRRLTLHLACSMHLSRYPMDHQNCEIAFASYAYTTADIEYIWDVPAIQIHEGANGAL 229
Query: 318 SQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
F++ SF + T G +S L+V L R +FL+Q+Y+P ++V ++WVS+WI
Sbjct: 230 PNFEIASFKNASCTSKTNTGTYSCLKVEIRLNRVFSFFLLQLYIPSSMLVGVAWVSYWI 288
Score = 34.7 bits (76), Expect = 6.3
Identities = 14/29 (48%), Positives = 17/29 (58%)
Query: 497 IDRAARVLFPASFALLNLFYWMIYAFSSD 525
ID AR++FP +F L N YW IY D
Sbjct: 468 IDIIARIIFPLAFILFNFAYWSIYLEEED 496
>UniRef50_A7SCG0 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 286
Score = 141 bits (341), Expect = 5e-32
Identities = 72/214 (33%), Positives = 110/214 (51%), Gaps = 5/214 (2%)
Query: 168 GYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL-----GPIRSLSLSIKM 222
G P +V + S+G + E M++S+D +FRQ WR+ RL +L G + L L+ +
Sbjct: 1 GGPVIVDVEAYVASIGAIDEKKMEFSVDIFFRQRWREERLCYLPQAGKGSGQRLILNPVL 60
Query: 223 LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDR 282
L+ WRPD + N K + H + N + IS G+IL S R+T C M R FPMD
Sbjct: 61 LKNTWRPDVFIKNSKEARFHEVPSDNVMYGISPDGNILLSSRITTTLSCQMNFRRFPMDV 120
Query: 283 QSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFSVL 342
Q C GSY ++ +V + + + + + +SQ+ + R+F G FS
Sbjct: 121 QKCHFQTGSYGHTEDDIVIRCRGGKGLIISDEVEISQYSITEVTSRDFKGVYNTGVFSEP 180
Query: 343 QVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
+ LKR Y++ Y+P L+V LSW+SFWI
Sbjct: 181 IATIVLKRRLMYYVYGYYLPAGLVVFLSWISFWI 214
>UniRef50_Q9TVI7 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 538
Score = 140 bits (340), Expect = 6e-32
Identities = 75/241 (31%), Positives = 123/241 (51%), Gaps = 9/241 (3%)
Query: 144 KNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWR 203
K T +L LL Y+ + +P KG V +LI+ + +SE+ +M F Q W
Sbjct: 86 KAATRILTELLSKYDRNLVPKM-KGVD--VDVELLIQRVSEISEIQSSSTMHILFSQIWH 142
Query: 204 DTRLSFLGP-----IRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGD 258
D LSF + +LSLS +M++ IW P+ N K S +H PN L I +G
Sbjct: 143 DPGLSFEHEEGAHCLTNLSLSHRMVDNIWLPNVCIVNSKGSAIHKSPTPNIFLAIFPNGT 202
Query: 259 ILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW-QNSQSVNFVPGMTL 317
+ + R+ +++ C M+ FPMDR C I SYA++ ++ W + Q V F+ + L
Sbjct: 203 VWMNYRVVVESPCEMDFSFFPMDRVMCTTIFESYAFNVGKVRLHWKRQGQPVEFIDDVKL 262
Query: 318 SQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIH 377
F + F + TF G + L + +R G++++Q+Y+P +V++SW+SFW+
Sbjct: 263 PDFHMTKFVHEKATFIYPAGVWDQLNIKLLFRRSYGFYILQIYLPTYCMVLISWISFWLD 322
Query: 378 R 378
R
Sbjct: 323 R 323
Score = 35.9 bits (79), Expect = 2.7
Identities = 16/49 (32%), Positives = 25/49 (51%)
Query: 478 RRQRQREAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIYAFSSDD 526
+R+++ +G + +DR + LFP +F NL YWM Y S D
Sbjct: 490 KRRKRLMSGKLFQRWTAEDMDRFCQKLFPITFTFCNLIYWMYYTAKSKD 538
>UniRef50_A7RT31 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 443
Score = 140 bits (340), Expect = 6e-32
Identities = 77/230 (33%), Positives = 122/230 (53%), Gaps = 15/230 (6%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
VL+ L Y+ P G G P V+T+ ++ + G + E +M YW D RL+
Sbjct: 38 VLKMLFDGYDKEARPNWG-GRPVEVRTDAIVEAFGNIQEANM----------YWTDKRLA 86
Query: 209 FLGPIR-SLSLSIKMLERIWRPDTYFYNGKHSYVHTITVP-NKLLRISQHGDILYSMRLT 266
G + S++L++ +PD Y YN + S + N L I G I YS ++
Sbjct: 87 --GKLNLSITLTVSAASNACKPDPYCYNARQSNMMLEDKDVNSRLSIDPDGKIFYSRGVS 144
Query: 267 IKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFP 326
I A C M+L +FP+D Q+C L GSYA+++ + ++W N ++ V L+QF L +
Sbjct: 145 IVASCEMDLHDFPLDTQNCYLKFGSYAFTDTDIFFRWNNPNKLSRVQKSDLAQFHLAGYD 204
Query: 327 YRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
T EG+++ ++V F + R GY++IQ Y P +LIVVLSW+ FW+
Sbjct: 205 LITETGIYEEGNYTTVKVIFKMNRRVGYYIIQAYCPDVLIVVLSWIIFWM 254
>UniRef50_Q09453 Cluster: Glycine receptor subunit beta-type 4
precursor; n=2; Caenorhabditis|Rep: Glycine receptor
subunit beta-type 4 precursor - Caenorhabditis elegans
Length = 473
Score = 140 bits (339), Expect = 9e-32
Identities = 75/262 (28%), Positives = 123/262 (46%), Gaps = 2/262 (0%)
Query: 125 QTDVFTWKQNKRSIN-DAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMG 183
Q + + + +N I D ++T +L+ + NY + P + T V + I M
Sbjct: 20 QAEFWDYDENVTQIEEDFKIDDVTRILKRV-GNYNRNAYPLLDQDLATHVDIQMYIEGMS 78
Query: 184 PVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHT 243
MD+ +D YF++ W D RL R L K+ +W PD YF N + + H
Sbjct: 79 SFHAQSMDFQVDIYFQEKWVDHRLQHNNTKRILVKDPKLFGLLWHPDLYFANARTASFHD 138
Query: 244 ITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW 303
+T PN L+ I +G + Y R+++ C +L +P+D Q+C L + SYAY +QL+ +W
Sbjct: 139 VTQPNFLVWIYPNGTVWYDCRISLTVLCMQDLARYPLDSQNCGLRILSYAYDEEQLIIRW 198
Query: 304 QNSQSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPC 363
V G+ + L + G +S F++ R + +IQ Y+P
Sbjct: 199 NGGNPVEVNRGIRMPDMHLKHIKFYTKRDKYATGIWSSAVAEFHVDREITHHIIQSYIPT 258
Query: 364 ILIVVLSWVSFWIHREVGSGEI 385
LIV++SW SFW+ E G +
Sbjct: 259 SLIVIISWFSFWLDVEAVPGRV 280
Score = 37.1 bits (82), Expect = 1.2
Identities = 13/24 (54%), Positives = 18/24 (75%)
Query: 497 IDRAARVLFPASFALLNLFYWMIY 520
IDR +R LFP +F + N+FYW+ Y
Sbjct: 437 IDRYSRALFPLAFIIFNIFYWIYY 460
>UniRef50_Q21005 Cluster: Putative uncharacterized protein acc-1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein acc-1 - Caenorhabditis elegans
Length = 466
Score = 139 bits (337), Expect = 1e-31
Identities = 70/236 (29%), Positives = 127/236 (53%), Gaps = 8/236 (3%)
Query: 145 NITSVLENLLKN-YENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWR 203
N T ++ LLK+ Y +P+H PT V+ ++ ++ + VSEL D+ +D Y ++W
Sbjct: 32 NDTEIINALLKDSYNKHYIPSH----PTHVRVDMWVQEVTSVSELTQDFEIDLYINEFWE 87
Query: 204 DTRLSF--LGPI-RSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDIL 260
D L + + P R++S K+L+R+W P+T F N K + +H N L + +G +
Sbjct: 88 DPALVYEDMNPCKRNISFDDKVLQRLWLPNTCFINSKSAAIHESPFKNVFLMVFSNGTLW 147
Query: 261 YSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQF 320
+ R+ + C M+L+ FP D+Q C L S+ Y+ ++ QW V + + L F
Sbjct: 148 TNYRMKLTGPCDMKLKRFPFDKQKCYLTFESFNYNTGEVRMQWNQPYPVILLKRIELPDF 207
Query: 321 DLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
L++F G + L V+F +R G++++Q Y+P ++ +V+SW+SF++
Sbjct: 208 KLVNFSVIAVEQMYPAGWWDELTVAFVFERRYGWYVLQGYIPTMVTIVISWISFYL 263
>UniRef50_A7LPG1 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 564
Score = 138 bits (335), Expect = 3e-31
Identities = 79/245 (32%), Positives = 126/245 (51%), Gaps = 10/245 (4%)
Query: 152 NLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLG 211
NLL+ N++ PT P V+ + + S+G +M + +D Y W+D RL+
Sbjct: 33 NLLQQ-SNTRPPTANASVPLGVKLGMYLESLGNFRSSEMSFDVDLYVYMSWQDPRLAHNF 91
Query: 212 PIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKC 271
L + ++ ++IW PD YF N + + +TVPN L ++ G + YS R T+ C
Sbjct: 92 SDYVLINNDEIRKQIWLPDLYFANARQASFQEVTVPNFNLFVAPDGTVAYSCRCTLTVAC 151
Query: 272 PMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDL--ISFPYRN 329
+ LR +PMD+Q C + + SYAY +Q+ W + V F + L +F + +S Y N
Sbjct: 152 SLNLRYYPMDQQLCSIRVLSYAYIAKQVNVTWFDKNPVRFNEEIGLPEFQIEHVSNAYCN 211
Query: 330 FTF-------TRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGS 382
++ + + DFS L + L R GY L+Q Y+P LIV++SWVSFWI R
Sbjct: 212 GSYQYALTENSYKSDDFSCLSGNLFLSRSIGYNLVQSYIPTGLIVMISWVSFWIDRRAVP 271
Query: 383 GEIVI 387
+ +
Sbjct: 272 ARVTL 276
Score = 39.1 bits (87), Expect = 0.29
Identities = 16/34 (47%), Positives = 20/34 (58%)
Query: 487 SRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
S H ID++ R LFPA+F L N+FYW Y
Sbjct: 521 SANHSRHALKIDKSCRYLFPAAFLLWNVFYWWYY 554
>UniRef50_UPI0000E48505 Cluster: PREDICTED: similar to inhibitory
glycine receptor; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to inhibitory glycine
receptor - Strongylocentrotus purpuratus
Length = 431
Score = 138 bits (333), Expect = 5e-31
Identities = 72/238 (30%), Positives = 124/238 (52%), Gaps = 4/238 (1%)
Query: 140 DAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFR 199
DA + ++S+ LL Y++ P G V ++ + S+ + E +DYS+
Sbjct: 31 DAEERLVSSLYNELLDGYDSRVRPCVN-GDAVHVFLDVFLASLDGIDEKHLDYSITATIH 89
Query: 200 QYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDI 259
Q W D RL+F G +L + +++R+W P+ N K +H I+ N+ + + G++
Sbjct: 90 QRWHDPRLTFNGTT-TLPPTAYLVDRVWHPNIVIGNAKEVLLHHISDTNQYVTVDWDGNV 148
Query: 260 LYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNF-VPGMTLS 318
RL++K C M+ FPMD Q C + L S+ + LV W +Q + F M L
Sbjct: 149 TLVQRLSVKLSCAMDFHRFPMDTQKCNMDLQSFGLTTSDLVLLW-GAQKLEFHSHHMRLP 207
Query: 319 QFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
Q+ + + + T R G FS ++ F L+R GY+++Q ++P I +V++SWV+FWI
Sbjct: 208 QYYMTGVDFFDCTEQRYNGIFSCVRAQFTLERTLGYYMLQAFIPSIALVMVSWVTFWI 265
>UniRef50_Q20828 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 517
Score = 136 bits (329), Expect = 1e-30
Identities = 70/237 (29%), Positives = 134/237 (56%), Gaps = 18/237 (7%)
Query: 148 SVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRL 207
+++E LL NY++ + P+ +V + ++ + V+E+ D+ MD Y + W D+ L
Sbjct: 68 TIIEKLLNNYKSFRTPSESG---VIVWIEVWVQEVNSVNEITSDFDMDIYVTELWMDSAL 124
Query: 208 SF--LGPIR-SLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
+ L P + +LSL+ ++L++IW+P+T F N K + +H N L I +G + + R
Sbjct: 125 RYEHLNPCKYNLSLNSEILDQIWKPNTVFINSKSANIHKSPFKNVFLMIYPNGTVWVNYR 184
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLI- 323
+ +K C M+ FPMD+QSC L L S++Y+NQ++ QW +N+ ++L + +++
Sbjct: 185 VQVKGPCSMDFSAFPMDQQSCHLTLESFSYNNQEVDMQW-----MNWTTPLSLLKKEIVL 239
Query: 324 -SFPYRNFTFTRRE-----GDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSF 374
F N++ + + G ++ L ++F R G+++ Q Y+P L + +SW+SF
Sbjct: 240 PDFVMSNYSTSLKHEIYPAGVWNELTMTFVFSRRYGWYIFQAYIPTYLTIFISWISF 296
>UniRef50_Q9N517 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 382
Score = 136 bits (328), Expect = 2e-30
Identities = 74/218 (33%), Positives = 112/218 (51%), Gaps = 9/218 (4%)
Query: 170 PTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRP 229
P V + S+G +M Y MD Y W+D + L +L++IW P
Sbjct: 10 PLQVHFGFYVESLGNFRATEMTYDMDMYLYMSWQDDSMRHNETEHVLVNDKDILDKIWLP 69
Query: 230 DTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLIL 289
D YF N + +Y H +TV N + IS G I Y R+T+ C ++L+++P+D Q+C + +
Sbjct: 70 DLYFANARTAYFHKVTVHNFNMFISPQGTISYGTRVTLNLACNLDLKDYPLDYQTCYIKV 129
Query: 290 GSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDL--ISFPYRN----FTFTR---REGDFS 340
SYA+ ++ W + + F P + L +F + + Y N +T T R G+FS
Sbjct: 130 ISYAHVKNEMNVSWFPNDPIRFNPEIDLPEFHIRALDKDYCNGVFLYTLTHNSSRVGEFS 189
Query: 341 VLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHR 378
L LKR G+ L+Q Y+P LIV +SWVSFWI R
Sbjct: 190 CLLGMLKLKRAIGFHLVQSYIPTGLIVAISWVSFWIDR 227
Score = 38.3 bits (85), Expect = 0.51
Identities = 14/24 (58%), Positives = 18/24 (75%)
Query: 497 IDRAARVLFPASFALLNLFYWMIY 520
ID+AAR FP FA+ N+FYW+ Y
Sbjct: 351 IDKAARFAFPCVFAIFNVFYWLYY 374
>UniRef50_UPI0000ECC613 Cluster: Gamma-aminobutyric-acid receptor
subunit beta-1 precursor (GABA(A) receptor subunit
beta-1).; n=1; Gallus gallus|Rep:
Gamma-aminobutyric-acid receptor subunit beta-1
precursor (GABA(A) receptor subunit beta-1). - Gallus
gallus
Length = 382
Score = 135 bits (326), Expect = 3e-30
Identities = 67/188 (35%), Positives = 108/188 (57%), Gaps = 3/188 (1%)
Query: 191 DYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKL 250
DY++ YF+Q WR+ RL + G +L+L + + +W DTYF N K+S+V + V +
Sbjct: 1 DYTLTMYFQQSWREKRLPYSGISLNLTLDNRAADHLWVSDTYFQNDKNSFVQGVMV-KQT 59
Query: 251 LRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQS-V 309
++ G +LY +R+T A C M+L +P+D Q+C L + S Y+ + + W +S V
Sbjct: 60 IQYHPDGTVLYGLRIT-TAACMMDLHRYPLDEQNCTLEIYSNGYTTNDIEFYWNGGKSAV 118
Query: 310 NFVPGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVL 369
V + L QF ++ + + G + L +SF LKR+TGYF +Q ++P LI +L
Sbjct: 119 TGVSNIELPQFSIVDYKTVSKRVEFPTGTYPQLSLSFWLKRNTGYFTLQTHMPSTLITIL 178
Query: 370 SWVSFWIH 377
S VSFWI+
Sbjct: 179 SRVSFWIN 186
>UniRef50_Q9NA62 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 434
Score = 133 bits (322), Expect = 1e-29
Identities = 78/258 (30%), Positives = 126/258 (48%), Gaps = 7/258 (2%)
Query: 147 TSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTR 206
T + L+ NY + LP P V+ I I+ + +S + +++D + W D R
Sbjct: 57 TDLARILMTNYSRNALPEPA---PVKVEVEITIQDISDISAITGTFTIDYWISAIWNDKR 113
Query: 207 LSF--LGPIR-SLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSM 263
L+F L P R +LSL M ++W P+ N K + VH PN LL I +G I +
Sbjct: 114 LAFSHLDPCRKNLSLDHDMEPKLWSPNVCIVNSKSTKVHDSPKPNILLMIFPNGTIWLNY 173
Query: 264 RLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPG-MTLSQFDL 322
R+ +A C M LRNFP+D C L+ SY+Y+ + QW V+ V L F +
Sbjct: 174 RIRSEAPCQMNLRNFPLDSIRCSLVFESYSYNAADVELQWLEWSPVSTVRNDYNLPDFRM 233
Query: 323 ISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGS 382
+ Y + T G + L VS + +R G++++Q+Y+P + V +SW++FW+ +
Sbjct: 234 TNITYGSVTEAYTAGMWHRLSVSIHFERLYGFYILQMYLPTYISVFISWIAFWMDTKALP 293
Query: 383 GEIVIDDSEWEELIEEVG 400
I + S L + G
Sbjct: 294 ARITLSVSSLMALTFQFG 311
Score = 37.5 bits (83), Expect = 0.89
Identities = 16/28 (57%), Positives = 18/28 (64%)
Query: 497 IDRAARVLFPASFALLNLFYWMIYAFSS 524
IDR A +LFP FAL NL YW Y +S
Sbjct: 401 IDRVASMLFPTMFALFNLVYWAYYLTTS 428
>UniRef50_Q22741 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 494
Score = 133 bits (322), Expect = 1e-29
Identities = 77/239 (32%), Positives = 118/239 (49%), Gaps = 10/239 (4%)
Query: 146 ITSVLENLLKN---YENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYW 202
+T + LKN Y PT G PT V ++ I M S MDY +D YF++ W
Sbjct: 30 LTKAFLDKLKNETLYNRFATPTQYDGVPTNVTLSMFIEGMSSFSAQTMDYHLDVYFQEEW 89
Query: 203 RDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYS 262
D RL+ L + + + +W PD YF N + + IT N L+ + +G + Y
Sbjct: 90 YDHRLAHNASAPILVRDLTVFKMMWHPDVYFANARSAAFQDITDDNFLVWVYPNGRVWYD 149
Query: 263 MRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFV---PGMTLSQ 319
R++I + C M+L +P+D Q C L + SYAY L W + V + P +T+
Sbjct: 150 ARISIVSSCNMDLWKYPLDSQECALRILSYAYPMTVLRLLWSEKEDVPAIDRNPDITMPD 209
Query: 320 FDL--ISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
L I Y N T+ G++S + F ++R + ++Q YVP LIVV+SW +FW+
Sbjct: 210 MSLKHIRTGYCNGTYA--TGEWSCMTAIFYVEREMMHHVMQTYVPTALIVVISWFNFWL 266
>UniRef50_Q10052 Cluster: Gaba/glycine receptor family (See gbr)
protein 3; n=4; Caenorhabditis|Rep: Gaba/glycine
receptor family (See gbr) protein 3 - Caenorhabditis
elegans
Length = 438
Score = 133 bits (322), Expect = 1e-29
Identities = 78/270 (28%), Positives = 133/270 (49%), Gaps = 18/270 (6%)
Query: 143 SKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYW 202
S + S+L +LL++Y+ + +P++ V + ++ + +SE+ + D +F Q W
Sbjct: 33 SNHRKSILTDLLQDYDKTMVPSNNS---VQVSVELTVQDISSISEISSSFIADVWFSQVW 89
Query: 203 RDTRLSF--LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDIL 260
D RL + + +LSL + ER+W P+ F N K + VH N LL I +G +
Sbjct: 90 YDPRLEYRNISCKTNLSLDSYVSERLWTPNVCFVNSKSTQVHKSPASNILLIIYPNGTVW 149
Query: 261 YSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQF 320
+ R+ + A C EL FP+D Q C L+ SY+Y+ ++ WQ V P F
Sbjct: 150 LNYRVQVSAPCSFELSRFPIDAQECHLVFESYSYNIAEVRLNWQQWAPVTMPPP---EDF 206
Query: 321 DLISFPYRNFTFTRREGDFSV-----LQVSFN-----LKRHTGYFLIQVYVPCILIVVLS 370
L F + N T+ + +++ L+V+F+ KR GY+++Q+Y+P L V +S
Sbjct: 207 RLPDFQFYNVTWGKTSNEYTAGMWDQLKVTFSQTFYRFKRLYGYYVLQMYLPTYLSVFIS 266
Query: 371 WVSFWIHREVGSGEIVIDDSEWEELIEEVG 400
W++FWI I + S L + G
Sbjct: 267 WIAFWIDTRALPARITLGVSSLMALTFQFG 296
>UniRef50_UPI0000EB6CC4 Cluster: glycine receptor, beta b; n=1;
Danio rerio|Rep: glycine receptor, beta b - Danio rerio
Length = 451
Score = 133 bits (321), Expect = 1e-29
Identities = 79/210 (37%), Positives = 112/210 (53%), Gaps = 8/210 (3%)
Query: 142 VSKNITS-VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQ 200
V N TS +L LL Y+ P KG P + NI I S G + E MDY ++ + RQ
Sbjct: 59 VPANSTSNILNKLLITYDPRIRPNF-KGIPVEDRVNIFINSFGSIQETTMDYRVNIFLRQ 117
Query: 201 YWRDTRLSFLGPIRSLSLSI--KMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGD 258
W D RL +S SL++ KM + +W+PD +F N K + H +T N LL I ++GD
Sbjct: 118 RWNDPRLRLPQDFKSDSLTVDPKMFKCLWKPDLFFANEKSANFHDVTQENILLFIFRNGD 177
Query: 259 ILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLS 318
+L SMRL++ CP++L FPMD Q C + L S+ Y+ L + WQ+ V + + L
Sbjct: 178 VLISMRLSVTLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLQFMWQSGDPVQ-MDEIALP 236
Query: 319 QFDL--ISFPYRNFT-FTRREGDFSVLQVS 345
QFD+ Y N T + G SVL +S
Sbjct: 237 QFDIKQEDIEYGNCTKYYAGTGILSVLSLS 266
Score = 34.3 bits (75), Expect = 8.3
Identities = 13/29 (44%), Positives = 17/29 (58%)
Query: 492 NSVSHIDRAARVLFPASFALLNLFYWMIY 520
++ ID AR LFP SF N+ YW +Y
Sbjct: 422 SAAKRIDLYARALFPFSFLFFNVIYWSVY 450
>UniRef50_Q621V5 Cluster: Putative uncharacterized protein CBG02331;
n=1; Caenorhabditis briggsae|Rep: Putative
uncharacterized protein CBG02331 - Caenorhabditis
briggsae
Length = 472
Score = 132 bits (319), Expect = 2e-29
Identities = 76/262 (29%), Positives = 129/262 (49%), Gaps = 17/262 (6%)
Query: 150 LENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF 209
L +LL++Y+ + +P++ V + ++ + +SE+ + D +F Q W D RL +
Sbjct: 75 LSDLLQDYDKTMVPSNNS---VQVSVELTVQDISSISEISSSFIADVWFSQVWEDPRLEY 131
Query: 210 --LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
+ +LSL + ER+W P+ F N K + VH N LL I +G + + R+ +
Sbjct: 132 RNISCKTNLSLDSYVSERLWTPNVCFVNSKSTQVHKSPASNILLIIYPNGTVWLNYRVQV 191
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPY 327
A C EL FP+D Q C L+ SY+Y+ ++ WQ V P F L F +
Sbjct: 192 SAPCSFELSRFPIDAQECHLVFESYSYNIAEVRLNWQQWAPVTMPPP---EDFRLPDFQF 248
Query: 328 RNFTFTRREGDFSV-----LQVSFN----LKRHTGYFLIQVYVPCILIVVLSWVSFWIHR 378
N T+ + +++ L+V+F+ KR GY+++Q+Y+P L V +SW++FWI
Sbjct: 249 YNVTWGKTSNEYTAGMWDQLKVTFSFFFRFKRLYGYYVLQMYLPTYLSVFISWIAFWIDT 308
Query: 379 EVGSGEIVIDDSEWEELIEEVG 400
I + S L + G
Sbjct: 309 RALPARITLGVSSLMALTFQFG 330
>UniRef50_Q4RN70 Cluster: Chromosome undetermined SCAF15016, whole
genome shotgun sequence; n=22; Eukaryota|Rep: Chromosome
undetermined SCAF15016, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 269
Score = 131 bits (317), Expect = 4e-29
Identities = 63/172 (36%), Positives = 107/172 (62%), Gaps = 3/172 (1%)
Query: 150 LENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF 209
++ L+K Y P G P V ++ I S+ +SE++MDY+ + RQ W D RL F
Sbjct: 29 IQRLMKGYNKYLRPFFDNG-PVTVGMSLDIASIDTISEINMDYTATIFLRQRWTDERLVF 87
Query: 210 LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKA 269
G +SLSL +++E +W PDT+ + K S++H ITV N+L+RI +G +LY++R+T
Sbjct: 88 EGN-KSLSLDGRLVELLWVPDTFIVDSKKSFLHDITVENRLIRIFPNGTVLYALRITTTV 146
Query: 270 KCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW-QNSQSVNFVPGMTLSQF 320
C M+L +PMD+Q+C L L S+ Y+ +++ W + ++SV+ + + L+Q+
Sbjct: 147 ACNMDLTKYPMDKQTCTLQLESWGYNINDVMFYWTRGNESVSGLDTLQLAQY 198
>UniRef50_Q9TZI5 Cluster: Expulsion defective (Defecation) protein
1; n=6; Caenorhabditis|Rep: Expulsion defective
(Defecation) protein 1 - Caenorhabditis elegans
Length = 539
Score = 131 bits (316), Expect = 5e-29
Identities = 69/231 (29%), Positives = 128/231 (55%), Gaps = 9/231 (3%)
Query: 157 YENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPI--- 213
Y++ Q+P + KG T V+ ++++ ++ VSE+ MDY+++ ++R+ WRD RL + +
Sbjct: 111 YDHRQVPENEKGEATYVEVSVVVSNIRAVSEVTMDYALELFYRESWRDPRLQYDRKLFKN 170
Query: 214 -RSLSLSIKMLERIWRPDTYFYNG---KHSYVHTITVPNKLLRISQHGDILYSMRLTIKA 269
L+L +W PDT+ N K+ ++I+ LLR+ + G +LYS R+++
Sbjct: 171 KTELALHESYTNFLWFPDTFVPNAIASKNPQRNSIS-HRSLLRLDETGKLLYSRRISLVC 229
Query: 270 KCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW-QNSQSVNFVPGMTLSQFDLISFPYR 328
+C M+L FP D+Q C L + SY Y+ +VY+W + +++ + + L F +
Sbjct: 230 ECTMDLTLFPFDKQLCKLGIESYGYTADHVVYKWSKGARTALELKKIRLPDFTIQEAYVT 289
Query: 329 NFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
+ + G++S L V F R +G+ +Q+ +P +V+ SWVS W+ E
Sbjct: 290 SQMESYATGNYSRLYVCFVFSRSSGFCFLQLIIPSTAVVITSWVSLWMETE 340
>UniRef50_Q8SWZ1 Cluster: RH55021p; n=4; Diptera|Rep: RH55021p -
Drosophila melanogaster (Fruit fly)
Length = 449
Score = 130 bits (314), Expect = 9e-29
Identities = 70/240 (29%), Positives = 123/240 (51%), Gaps = 9/240 (3%)
Query: 156 NYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRS 215
NY P KG P +V +I + + ++ DMD+ +D + Q W ++RL I
Sbjct: 43 NYVKEIRPPSKKGSPVIVDFSIFVVDINSINVEDMDFRVDMFIHQRWLESRLEIPDDIFE 102
Query: 216 -----LSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAK 270
++L ++ E W+PD YF N K + + T+T + + ++ + Y+ R+
Sbjct: 103 EGDDYVTLLPEVFENFWQPDPYFLNSKIAEIATLTHKFTSVTLYKNKTVRYAARMHAIIA 162
Query: 271 CPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDL---ISFPY 327
C ME + +PMD Q CP+ + S++ +NQ++ +W +S V P + L Q++L +
Sbjct: 163 CQMEFQLYPMDIQVCPIYIESFSSNNQKVKLRWSDS-GVTLNPELKLLQYNLGQPLELEE 221
Query: 328 RNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVI 387
+ + G+FS L V F +R G+ LIQ + P L+V+LSW SFW+ + G + +
Sbjct: 222 SDGYMPEKVGNFSRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRVTL 281
>UniRef50_O01792 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 469
Score = 129 bits (311), Expect = 2e-28
Identities = 79/267 (29%), Positives = 139/267 (52%), Gaps = 13/267 (4%)
Query: 128 VFTWKQNKRSINDAVSK-NIT--SVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGP 184
V T+ Q++ S + +K +T ++L+ ++ NY S LP G P VQ + ++ +
Sbjct: 11 VTTFAQDEGSFVEKCTKPRLTPAAILDVIMANYSRS-LP----GNPVGVQVEVTVQDVME 65
Query: 185 VSELDMDYSMDCYFRQYWRDTRLSF--LGPIR-SLSLSIKMLERIWRPDTYFYNGKHSYV 241
+S L ++ D +F W D RL++ L R +LS + + IW P+ N K ++V
Sbjct: 66 LSVLSNSFTADIWFSSIWYDPRLAYSHLDNCRQNLSFDDRFEKLIWSPNVCIVNTKSAHV 125
Query: 242 HTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVY 301
H PN LL + +G I + R+ +++ C M+L FP+D Q C L+ SY+Y+ +
Sbjct: 126 HRSPKPNVLLMLLPNGTIWLNYRIRVQSPCSMDLARFPIDTQYCQLVFESYSYNTASVSV 185
Query: 302 QWQNSQSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQV-Y 360
W + V +P ++L+ FDL + T + G++ L V F R G++++QV Y
Sbjct: 186 NWM-ANPVTVLPEISLADFDLSRYRTSRHTEVYKAGEWYRLTVEFEFTRKYGFYILQVLY 244
Query: 361 VPCILIVVLSWVSFWIHREVGSGEIVI 387
VP + + +SW++F I + IV+
Sbjct: 245 VPTYISLFISWIAFCIDTKALPARIVL 271
>UniRef50_O17402 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 563
Score = 128 bits (310), Expect = 3e-28
Identities = 70/227 (30%), Positives = 112/227 (49%), Gaps = 7/227 (3%)
Query: 157 YENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSL 216
Y P +G T V + I SM MD+ +D Y W D RL+ L
Sbjct: 134 YNMFMAPGQSQGKRTDVHVAVYIESMSSFKAQSMDFEVDMYLAMGWFDRRLAHNCTHPIL 193
Query: 217 SLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELR 276
S + +RIW PD YF N K++Y+ +T PN ++ + G I +MRL + C M+L+
Sbjct: 194 VTSKLIADRIWYPDLYFVNSKYAYLQEVTTPNLMVIVYPDGLIFKTMRLDVTLSCMMDLK 253
Query: 277 NFPMDRQSCPLILGSYAYSNQQLVYQWQNSQ---SVNFVPGMTLSQFDLISFPYRN---- 329
FP+D Q CPL + S+AY Q + W++ + F P + L+ + + +
Sbjct: 254 LFPLDYQECPLTIQSFAYIEQIVNLTWRDDPPNFPIGFNPDIKLNDMQITNKRFVKCAGP 313
Query: 330 FTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
+ R E +S +Q +KR + +IQ Y+P ++V +SW+SFW+
Sbjct: 314 YPMFRGEAAWSCIQGYIVMKRLVLFHIIQTYIPTGMLVSISWMSFWL 360
>UniRef50_Q7YTP9 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 679
Score = 128 bits (309), Expect = 4e-28
Identities = 75/239 (31%), Positives = 122/239 (51%), Gaps = 7/239 (2%)
Query: 140 DAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFR 199
D S I VL+++ +Y+N+ +P P V + M++SMD
Sbjct: 315 DYGSSYILPVLKSV--DYDNTSVPLAFNDIPVNVAVAFNFLYLANFDSEMMEFSMDVEME 372
Query: 200 QYWRDTRL--SFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHG 257
W D RL ++ PIR I +E+IWRPD Y N KHSY H ++ PN +RI+ G
Sbjct: 373 FSWIDIRLVNNYTKPIRIREKPI--IEQIWRPDPYIVNSKHSYFHYVSFPNIRMRITPEG 430
Query: 258 DILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTL 317
+ Y++R++ C M +P DRQ C L + S AYSNQ + + W +S + F +TL
Sbjct: 431 LVTYTVRVSSVCSCFMSFCLYPHDRQECDLRISSIAYSNQYVKFHW-HSNPIKFQSKITL 489
Query: 318 SQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
+ + + + D S L++ F+L+R + F+I+ YVP L ++ +WV+ ++
Sbjct: 490 PELHITKIKTAECSTKGKLVDASCLRIIFSLERDSARFVIEKYVPSTLAMMFAWVAPYV 548
>UniRef50_Q95Y52 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 508
Score = 127 bits (307), Expect = 6e-28
Identities = 64/233 (27%), Positives = 119/233 (51%), Gaps = 7/233 (3%)
Query: 145 NITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 204
N + +L ++ NY ++P G V+ + ++ + +S++ D+ +D Y + W D
Sbjct: 65 NDSFILGTIMSNYNRHKIP----GGQVDVEVEVWVQEITTISDITSDFQLDIYIYETWYD 120
Query: 205 TRLS--FLGPIR-SLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILY 261
L+ F+ P + +LSL+ +LE++W P++ F N K + +H PN L I +G +
Sbjct: 121 PALNYAFMNPCKYNLSLNSVLLEKLWTPNSCFINSKTADIHKSPFPNIFLMIYANGTVWT 180
Query: 262 SMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFD 321
+ RL ++ C M+L FP D +C L S+ Y+ ++ W + M L+ ++
Sbjct: 181 NYRLKLQGPCIMDLTKFPFDNVTCSLTFESFNYNTDEVKMDWSVNGVQKMRDKMELADYE 240
Query: 322 LISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSF 374
L+ T G + L +SF KR G++++Q Y+P L + +SW+SF
Sbjct: 241 LVDIHKIRTTEEYPAGYWHELTMSFEFKRRAGWYILQAYLPTYLTICISWISF 293
>UniRef50_O17041 Cluster: Putative uncharacterized protein T15B7.16;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein T15B7.16 - Caenorhabditis elegans
Length = 435
Score = 127 bits (306), Expect = 9e-28
Identities = 83/282 (29%), Positives = 134/282 (47%), Gaps = 24/282 (8%)
Query: 139 NDAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYF 198
ND +S+ + L + NY + +P K TVV I+++ VSE+ +++D F
Sbjct: 29 NDTISQLVLRRLFD--DNYNKNTVPL--KTSATVVSVEFGIQNIAQVSEISASFTLDLLF 84
Query: 199 RQYWRDTRLSF---LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQ 255
Q W D RL F +++L+L M+E++W P+ F N K + +H+ PN L I
Sbjct: 85 SQIWHDPRLRFDHLTNCLQNLTLGYSMVEKLWTPNVCFVNSKKTEIHSSPTPNIFLMIYP 144
Query: 256 HGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGM 315
+G + + RL +++ C ++L FPMD +C LI+ SYAY+ ++ W+ Q V +
Sbjct: 145 NGTVWVNYRLQVQSPCMVDLVLFPMDIMNCELIIESYAYNAAKVKLNWREWQPVFSIAKS 204
Query: 316 TLSQFDLISFPYRNFTFTRREG-----------------DFSVLQVSFNLKRHTGYFLIQ 358
LS F L + +F G D L VS R G++++Q
Sbjct: 205 KLSDFTLYGLQWTKNSFEYAAGQWDQVSSFCSLNCFSKMDGFQLTVSLTFSRAYGFYILQ 264
Query: 359 VYVPCILIVVLSWVSFWIHREVGSGEIVIDDSEWEELIEEVG 400
+Y+P V LS+VSFWI + I + S L + G
Sbjct: 265 MYIPTYSSVFLSFVSFWIDLKALPARITLGVSSLMALTFQYG 306
>UniRef50_A7SQS7 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 155
Score = 127 bits (306), Expect = 9e-28
Identities = 63/152 (41%), Positives = 93/152 (61%), Gaps = 3/152 (1%)
Query: 145 NITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 204
NIT +LE LL Y+ P G G P V I +G ++E++M+++ YFRQYW D
Sbjct: 1 NITYLLETLLSGYDKRLRPNFG-GAPVNVSVTTFIEFIGDINEINMEFTTIMYFRQYWED 59
Query: 205 TRLSFL--GPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYS 262
RL++ G + L+ + +ML+ IW PDT+F K + IT N+++RI +G +LYS
Sbjct: 60 PRLAYADTGYTKRLAFNPEMLKFIWVPDTHFPGIKDGLKNDITASNEVVRIFPNGTLLYS 119
Query: 263 MRLTIKAKCPMELRNFPMDRQSCPLILGSYAY 294
MRL + ++CPM+LRNFPMD Q C L + + Y
Sbjct: 120 MRLKVTSQCPMDLRNFPMDSQKCRLKMEACKY 151
>UniRef50_Q8MM20 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 428
Score = 126 bits (304), Expect = 1e-27
Identities = 96/385 (24%), Positives = 168/385 (43%), Gaps = 30/385 (7%)
Query: 145 NITSVLENLLKN----YENSQLPTHGKGYPTV-VQTNILIRSMGPVSELDMDYSMDCYFR 199
N T ++++LL + Y +LP+ P V V+ + ++ + VSEL D+ +D Y
Sbjct: 56 NDTEIIDHLLIDRALYYNKHKLPS-----PQVDVRIEMWVQEVTSVSELTQDFEIDLYMN 110
Query: 200 QYWRDTRLSF--LGPIR-SLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQH 256
+YW D L++ L P + +LS +++ IW P+T F N K + +H+ N L + +
Sbjct: 111 EYWTDPGLAYDILNPCQGNLSFDWAVMQNIWTPNTCFINSKKAQLHSSPFTNVFLMVFPN 170
Query: 257 GDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMT 316
G + + R+ C M+L FPMD C L S+ Y+ ++ +W + F P +
Sbjct: 171 GSVWSNWRIKSTGPCVMDLTKFPMDSIECTLTFESFNYNKDEVFMRWGDPPLTIFKP-IE 229
Query: 317 LSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
L F + +F N G +S L V+F +R +G++L+Q Y+P + V +SW+ F++
Sbjct: 230 LPDFTMTNFSTSNKFQLYAAGYWSELNVNFLFRRRSGWYLLQGYIPTYMTVFISWIPFYL 289
Query: 377 HREVGSGEIVIDDSEWEELIEEVGGDXXXXXXXXXXXXXXXXXXTN-NLSMPSQSSNPTT 435
+ +I + L + G + S T
Sbjct: 290 GPKAIPARTMIGVNALLALTFQFGNIIRNLPRVSYIKAIDVWMLSGICFVFASLFELATI 349
Query: 436 SDNLETEQPVAVRLTMERTTQTETRVPRWRQLLYCLAGDDRYRRQRQREAGSRGHINSVS 495
+ E A + R+T+ RW+Q C R QR++ +I
Sbjct: 350 GFLMRNEGKPATK--SSRSTKNSN---RWQQPSVC-------REDTQRKS---QNIVFCE 394
Query: 496 HIDRAARVLFPASFALLNLFYWMIY 520
+D +R++FP F N YW +Y
Sbjct: 395 RLDNTSRLMFPVVFTFYNFIYWFVY 419
>UniRef50_Q0GQQ5 Cluster: Cys-loop ligand-gated ion channel subunit;
n=3; Endopterygota|Rep: Cys-loop ligand-gated ion
channel subunit - Apis mellifera (Honeybee)
Length = 391
Score = 126 bits (304), Expect = 1e-27
Identities = 69/233 (29%), Positives = 118/233 (50%), Gaps = 9/233 (3%)
Query: 163 PTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRS-----LS 217
P +G P +V NI + + ++ DMD+ +D + RQ W ++RL I ++
Sbjct: 3 PPSKQGLPVLVDFNIFVADINSINVEDMDFRVDMFVRQSWIESRLDMPDYIFEEGDDYVT 62
Query: 218 LSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRN 277
L + + +W+PD YF N K S + + + + ++ + YS R+ C ME +
Sbjct: 63 LPPEFFDSLWQPDPYFLNAKVSEIAALNHKFSSVTLYRNKTVKYSARMHAIIACQMEFQL 122
Query: 278 FPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRNFT---FTR 334
+PMD Q CP+ + S++Y Q+L +W + +V P + L Q+D+ T
Sbjct: 123 YPMDIQICPIYIESFSYHKQKLRLRW-GTGAVTVNPELKLLQYDIGKPVVAEETVDYMLE 181
Query: 335 REGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVI 387
+ G+FS L V F +R G+ LIQ + P L+V+LSW SFW+ + G + +
Sbjct: 182 KSGNFSRLVVFFRFERQIGHHLIQTFAPSTLVVMLSWFSFWLGLDAIPGRVAL 234
>UniRef50_UPI00015B5BFB Cluster: PREDICTED: similar to cys-loop
ligand-gated ion channel subunit; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to cys-loop
ligand-gated ion channel subunit - Nasonia vitripennis
Length = 435
Score = 124 bits (298), Expect = 8e-27
Identities = 69/233 (29%), Positives = 119/233 (51%), Gaps = 10/233 (4%)
Query: 163 PTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS-----FLGPIRSLS 217
PT G+ P VV NI + + ++ DMD+ +D + Q W ++RL F ++
Sbjct: 49 PTTGRT-PVVVSFNIFVVDINSINVEDMDFRVDMFIYQTWTESRLRMPIDIFEDDEDYVT 107
Query: 218 LSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRN 277
L + + +W+PD YF N K S + T+ + + + ++ + YS R+ C ME +
Sbjct: 108 LPPEFFDNLWQPDPYFLNSKVSEIATLNSKHSSVTLYRNKTVRYSARMHAIIACQMEFQF 167
Query: 278 FPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDL---ISFPYRNFTFTR 334
+PMD Q CP+ + S++Y +++L +W V P + L Q++L +
Sbjct: 168 YPMDIQICPMQIESFSYDSEKLSLRW-GPDGVIVNPELKLLQYNLEDPLKIDESVSFIDE 226
Query: 335 REGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVI 387
+ G+FS L V F +R G+ LIQ + P L+V+LSW SFW+ + G + +
Sbjct: 227 KNGNFSRLIVYFQFERQIGHHLIQTFAPSTLVVMLSWFSFWLGLDAIPGRVAL 279
>UniRef50_Q21420 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 457
Score = 123 bits (296), Expect = 1e-26
Identities = 67/234 (28%), Positives = 122/234 (52%), Gaps = 10/234 (4%)
Query: 148 SVLENLLKN--YENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDT 205
++++ LL Y ++P G P VQ ++++ ++E+ D+ MD Y + W D
Sbjct: 56 AIIDKLLNGTGYNKFRIPNEN-GVP--VQVEFWVQAITSINEITNDFEMDIYINEMWLDP 112
Query: 206 RLSF--LGPIR-SLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYS 262
L F L P + +LS+S ++LE++W P++ F N K + +H N L I +G + +
Sbjct: 113 ALKFDHLNPCKQNLSVSHQVLEQLWTPNSCFVNSKFAEIHDSPFKNVFLMIYPNGTVWVN 172
Query: 263 MRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW--QNSQSVNFVPGMTLSQF 320
R+ +K C + L FP+D Q C LI S+ Y+NQ++ +W ++++ V+ + L F
Sbjct: 173 YRVNVKGPCDLSLELFPLDIQECHLIYESFNYNNQEVRMRWNEKSAEPVSVTNKIRLPDF 232
Query: 321 DLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSF 374
+LI + G + L V +R ++ +Q Y+P L + +SW+SF
Sbjct: 233 ELIKIESTRISAPYPAGMWDELHVKLVFERRYIWYFMQAYLPTYLTIFISWISF 286
Score = 35.9 bits (79), Expect = 2.7
Identities = 13/28 (46%), Positives = 18/28 (64%)
Query: 493 SVSHIDRAARVLFPASFALLNLFYWMIY 520
S IDR + ++FPA FA+ N+ YW Y
Sbjct: 412 SPEKIDRVSAIMFPACFAIFNIVYWSYY 439
>UniRef50_P41849 Cluster: Uncharacterized glycine receptor-like
protein T20B12.9; n=2; Caenorhabditis|Rep:
Uncharacterized glycine receptor-like protein T20B12.9 -
Caenorhabditis elegans
Length = 476
Score = 123 bits (296), Expect = 1e-26
Identities = 69/260 (26%), Positives = 130/260 (50%), Gaps = 8/260 (3%)
Query: 145 NITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 204
N+ +++ LL +Y+ LP +G ++ ++ + + +SE+ D+S+D + + W+D
Sbjct: 15 NLGKLIDTLLTDYDTHLLP-EAEGVNVTIELHV--QGVSGISEITGDFSLDVMYSEIWQD 71
Query: 205 TRLSFLG-PIRSLSLSIKMLE---RIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDIL 260
RLSF + + ++++K+ + +IW PDT N K S +H+ N + + ++G +
Sbjct: 72 PRLSFKHLNVCATNITLKVSDFRKKIWTPDTCIINSKSSSIHSSPSENTFVILYENGLVW 131
Query: 261 YSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQF 320
+ RL +K C + L+ FP D SC ++L SY+++ ++ W + + + + L F
Sbjct: 132 SNFRLNVKTPCSVNLKMFPFDSLSCEIVLESYSFNTDEVRLMW-HDVPITMMEKVELPDF 190
Query: 321 DLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREV 380
DLI + + G + +V F R G++L Q Y P L V+ SWV F+
Sbjct: 191 DLIGWSTDHQRLEYPNGIWDRAKVKFTFARRYGFYLFQSYFPTSLTVISSWVGFFFDVRS 250
Query: 381 GSGEIVIDDSEWEELIEEVG 400
S I + S L + G
Sbjct: 251 VSARITLGVSSLLALTFQFG 270
Score = 36.3 bits (80), Expect = 2.1
Identities = 15/35 (42%), Positives = 21/35 (60%), Gaps = 1/35 (2%)
Query: 491 INSVSHIDRAARVLFPASFALLNLFYWMIYAFSSD 525
I SV +DR + ++FP SF + N+ YW IY D
Sbjct: 440 ITSVQ-VDRCSMIMFPLSFLIFNVVYWSIYFMKMD 473
>UniRef50_Q9U358 Cluster: Putative uncharacterized protein acc-4;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein acc-4 - Caenorhabditis elegans
Length = 408
Score = 119 bits (286), Expect = 2e-25
Identities = 68/239 (28%), Positives = 122/239 (51%), Gaps = 11/239 (4%)
Query: 148 SVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRL 207
+++ +L Y LP G G+ VV I ++ + + E+ ++ +D Y + W D L
Sbjct: 54 AIIAQILDGYNKLDLP--GGGH-VVVSIEIWVQEVSKIIEITSEFELDIYVTERWTDPSL 110
Query: 208 SF--LGPIRSLSLSIK---MLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYS 262
++ L P +S ++S+ +L +IW P F N K + +H N L+I +G I ++
Sbjct: 111 AYSHLNPCKS-NMSVDGATILNKIWNPHACFVNSKLANIHESPFKNIFLQIYSNGSIWHN 169
Query: 263 MRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNS-QSVNFVPG-MTLSQF 320
R+ + C LR FP+D+Q C L S+ ++ Q+ +W + + + G +TL +
Sbjct: 170 YRIKLTGPCSSTLRTFPIDQQRCMLFYESFTHNTDQVKMEWITTVPPITILKGNITLPDY 229
Query: 321 DLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
L+ F + G F+ L +F +R G++++QVYVP + V +SWVSF + E
Sbjct: 230 VLVDFSSSSELRLYPPGIFNELIATFTFQRLYGFYILQVYVPAYISVFISWVSFTLGAE 288
>UniRef50_A7SAV3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 373
Score = 119 bits (286), Expect = 2e-25
Identities = 69/198 (34%), Positives = 112/198 (56%), Gaps = 17/198 (8%)
Query: 191 DYSMDCYFRQYWRDTRLSFLGPIRSLSLSI--KMLERIWRPDTYFYNGKHSYVHTITVPN 248
D+SM YFRQ+WRD+RL++ S++I +L++IW PDT+F K T
Sbjct: 1 DFSMTIYFRQWWRDSRLAYGDMYHRDSVTIGGDILKQIWLPDTHFEYEKKPKDRTRDHVF 60
Query: 249 KLLRISQHGDILYSMRLTIKA---KCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQ- 304
LL++ + G I++S R I + C M+LR++PMD Q C + S+ Y +VY+W+
Sbjct: 61 -LLKLWRDGTIMWSRRQVIDSITTTCAMDLRSYPMDTQRCNFSIESFGYPINDVVYKWRL 119
Query: 305 --NSQSVNFVPGMTLSQFDLISFPYRNFTFTRRE----GDFSVLQVSFNLKRHTGYFLIQ 358
+ + + + L++F L ++ TFT+ G FS + F + R Y++IQ
Sbjct: 120 GRSDEDIKVKQDLALTKFTL----WKIQTFTKISHYVTGSFSGIVAEFTMTRRALYYVIQ 175
Query: 359 VYVPCILIVVLSWVSFWI 376
+++PC +IV LSW+SFWI
Sbjct: 176 IFLPCAMIVFLSWISFWI 193
Score = 36.7 bits (81), Expect = 1.6
Identities = 14/27 (51%), Positives = 20/27 (74%)
Query: 494 VSHIDRAARVLFPASFALLNLFYWMIY 520
V+ +DR +RVLFP+ F + N+ YW IY
Sbjct: 345 VNLVDRYSRVLFPSFFLVFNIIYWPIY 371
>UniRef50_Q4SC79 Cluster: Chromosome undetermined SCAF14659, whole
genome shotgun sequence; n=2; Euteleostomi|Rep:
Chromosome undetermined SCAF14659, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 481
Score = 117 bits (281), Expect = 9e-25
Identities = 56/142 (39%), Positives = 85/142 (59%), Gaps = 1/142 (0%)
Query: 150 LENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF 209
L++L+K Y + P G G P V I + S+ +SE +M+Y+M + RQ W D RLS+
Sbjct: 32 LDDLMKGYARNFRPGIG-GPPVNVAMAIEVASIDHISEANMEYTMTVFLRQSWHDDRLSY 90
Query: 210 LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKA 269
++L L + ++++W PDT+ N K ++ H +TV NKL+R+ +G ILYS R+T
Sbjct: 91 NHTNKTLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPNGVILYSSRITSTV 150
Query: 270 KCPMELRNFPMDRQSCPLILGS 291
C M+L +PMD Q C L L S
Sbjct: 151 ACDMDLTKYPMDEQECRLDLES 172
Score = 70.1 bits (164), Expect = 1e-10
Identities = 35/110 (31%), Positives = 60/110 (54%), Gaps = 5/110 (4%)
Query: 280 MDRQSCPLILGSYAYSNQQLVYQWQNSQS-VNFVPGMTLSQFDLISFPYRNFTFT-RREG 337
+++ C + G YS++ +VY W SQ V+ + + LSQF + + + + G
Sbjct: 197 LEKHHCVFVDG---YSSEDIVYHWSESQQHVHGLDKLELSQFTITDYRFDTEMMNFKSAG 253
Query: 338 DFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVI 387
F L + F L+R+ G ++IQ Y+P IL+V +SWVSFWI + + +
Sbjct: 254 RFPRLSLCFQLRRNRGVYIIQSYMPSILLVAMSWVSFWISQSAVPARVTL 303
>UniRef50_UPI0000F1E22C Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 447
Score = 114 bits (275), Expect = 5e-24
Identities = 53/119 (44%), Positives = 73/119 (61%), Gaps = 3/119 (2%)
Query: 264 RLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFV---PGMTLSQF 320
RLTI A+CPM+L +FPMD +CPL GSYAY ++VY+W + V G L+Q+
Sbjct: 160 RLTISAECPMQLEDFPMDAHACPLKFGSYAYPISEVVYKWTKGPGKSVVVAEEGSRLNQY 219
Query: 321 DLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
LI + G ++V+ F LKR GYF+IQ Y+PC + V+LS VSFW++RE
Sbjct: 220 HLIGHTAGTEDISTSRGQYTVMMAHFYLKRKIGYFVIQTYMPCFMTVILSQVSFWLNRE 278
Score = 38.7 bits (86), Expect = 0.39
Identities = 15/29 (51%), Positives = 19/29 (65%)
Query: 492 NSVSHIDRAARVLFPASFALLNLFYWMIY 520
NSVS ID+ +R++FP F NL YW Y
Sbjct: 408 NSVSKIDKMSRIVFPVLFGTFNLVYWATY 436
>UniRef50_A7SCG4 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 270
Score = 114 bits (275), Expect = 5e-24
Identities = 68/194 (35%), Positives = 100/194 (51%), Gaps = 12/194 (6%)
Query: 191 DYSMDCYFRQYWRDTRLSF-LGPIRSLSLSIKMLER-----IWRPDTYFYNGKHSYVHTI 244
D+S + Y RQ W D L + + + + S +L+ +W+PDTY N K +
Sbjct: 1 DFSFEFYMRQRWIDPTLKYNKSSLYNKNYSYAILDHTLVNNLWKPDTYIENLKRLEMGFS 60
Query: 245 TVP--NKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQ 302
P N+ LR+ +G +L S R++ C M NFPMDRQSC + + SY ++ L Y
Sbjct: 61 GGPFINEGLRLFPNGLVLISSRVSATLSCAMNFHNFPMDRQSCSVTISSYFFTEDDLYYD 120
Query: 303 WQNSQSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVP 362
W + V+ G LSQFDL+ + G +S L +F +R +L+ YVP
Sbjct: 121 WND---VSIYKG-NLSQFDLLGLDSLRKSLVFTSGTYSSLVATFRFRRRIQNYLLSFYVP 176
Query: 363 CILIVVLSWVSFWI 376
IL V+LSWVSF+I
Sbjct: 177 TILTVMLSWVSFFI 190
>UniRef50_P91985 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 400
Score = 111 bits (268), Expect = 3e-23
Identities = 65/240 (27%), Positives = 121/240 (50%), Gaps = 17/240 (7%)
Query: 145 NITSVLENLLKN--YENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYW 202
N ++E LLK Y ++P V I+ + +SE+ D+ ++ + + W
Sbjct: 70 NEAQLMEKLLKGSGYSKHKIPRENG---ITVSVEFWIQEINSISEMTNDFELELFINEMW 126
Query: 203 RDTRLSF--LGPIRS-LSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDI 259
D L F LG ++ L+L + L ++W P+T F N K + ++ + N L + +G +
Sbjct: 127 TDPSLRFPHLGACKANLTLDQQTLTKLWTPNTCFVNSKFAEIYESSFQNVFLTLFDNGTV 186
Query: 260 LYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQ 319
+ R+ +K C M+L +FPMD QSC L S+ Y+N+++ QW + +S P L +
Sbjct: 187 WVNYRVRVKGACNMDLVDFPMDTQSCRLNYQSFTYNNEEVRLQWNSQRS----PVFALQE 242
Query: 320 FDLISFPYRNFT--FTRRE---GDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSF 374
+ F ++ T +R+ G + L V+F +R ++ +Q Y+P + +SW++F
Sbjct: 243 IRIADFWLKDITPAVIKRDYPAGLWDELVVTFVFERRYMWYFLQAYLPTFFSIFISWIAF 302
>UniRef50_Q4SJX0 Cluster: Chromosome 1 SCAF14573, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 1 SCAF14573, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 371
Score = 109 bits (261), Expect = 2e-22
Identities = 44/108 (40%), Positives = 74/108 (68%)
Query: 186 SELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTIT 245
+++ DY++ YF+Q WRD RLS+ +L+L ++ +++W PDTYF N K S+VH +T
Sbjct: 84 ADMAHDYTLTMYFQQAWRDKRLSYSEIAYNLTLDNRVADQLWVPDTYFLNDKKSFVHGVT 143
Query: 246 VPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYA 293
V N+++R+ G +LY +R+T A C M+LR +P+D Q+C L + S++
Sbjct: 144 VKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESWS 191
Score = 72.5 bits (170), Expect = 3e-11
Identities = 31/95 (32%), Positives = 54/95 (56%), Gaps = 1/95 (1%)
Query: 294 YSNQQLVYQWQNSQ-SVNFVPGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHT 352
Y+ + + W+ +V+ V + L QF ++ + + G + L +SF LKR+
Sbjct: 228 YTTDDIEFYWRGGDGAVSGVDKIELPQFSIVDYKLISKNVVFSTGSYPRLSLSFKLKRNI 287
Query: 353 GYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVI 387
GYF++Q Y+P ILI +LSWVSFWI+ + + + +
Sbjct: 288 GYFILQTYMPSILITILSWVSFWINYDASAARVAL 322
>UniRef50_A7RF65 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 290
Score = 106 bits (255), Expect = 1e-21
Identities = 72/251 (28%), Positives = 119/251 (47%), Gaps = 19/251 (7%)
Query: 144 KNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWR 203
K T + NLL+NY+ P + + + + G + E +MD+S++ Y Q W
Sbjct: 3 KQATEAMNNLLRNYDKRIRP-YSNTDKLNITVQLAVERFGDIREKEMDFSLEVYLNQTWH 61
Query: 204 DTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKL-----LRISQHGD 258
D RL+ + LS + +W+PDT YV ++TV N L + I G
Sbjct: 62 DDRLNHTLD-HPIILSGEFKGSVWQPDTIIL-----YVRSLTVYNSLSEPSSITIYSDGT 115
Query: 259 ILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYS-NQQLVYQWQNSQSVNFVPGMTL 317
+ ++RL + C M+LR++P+D Q C L + S + N Y+ + F + L
Sbjct: 116 VRSTVRLALVINCLMDLRDYPLDEQECSLAMLSCNLTVNSHNNYKML--VVIAFFSTVVL 173
Query: 318 SQFDLI-SFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
+ + S + F G++S + +F KR Y L+Q+Y P +LIV LSW+SFWI
Sbjct: 174 PRISIYKSMSLNSVLFV---GNWSRVTTTFLFKRQIEYALLQIYAPTMLIVSLSWLSFWI 230
Query: 377 HREVGSGEIVI 387
+E + +
Sbjct: 231 SKEAVPARVTL 241
>UniRef50_UPI0000D56CB7 Cluster: PREDICTED: similar to CG6927-PA;
n=2; Tribolium castaneum|Rep: PREDICTED: similar to
CG6927-PA - Tribolium castaneum
Length = 534
Score = 104 bits (250), Expect = 5e-21
Identities = 75/276 (27%), Positives = 125/276 (45%), Gaps = 14/276 (5%)
Query: 135 KRSINDAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSM 194
K S++ +T++L N + + S+ T G P V I + + +L M
Sbjct: 77 KPSMSSLSQDQLTTILTNPCRYDKLSKPATEG---PLPVYMQIDLTHIESADQLQFKAHM 133
Query: 195 DCYFRQYWRDTRLSF--LGPIRSLSLSIKMLE-RIWRPDTYFYNGKHSYVHTITVPNKLL 251
+ ++D+RL + + P R + ++L +IW P N + + V I + +
Sbjct: 134 --LVQYLYKDSRLRYKDVFPQRGDLIGEELLRSKIWVPHVMVRNERDARVMGIDGKDVFV 191
Query: 252 RISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNF 311
I GD++YS R+T C M L+ FP D Q C L S+ Y+ L+ W + V
Sbjct: 192 LIKPTGDVVYSYRMTATFYCWMNLQKFPFDTQDCYLRWDSWTYNTTNLILHWDKNNPVKI 251
Query: 312 VPGMTLSQFDLI-SFPYR-----NFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCIL 365
+ L++F L S P +F G+FS L F LKR GY+++ ++P IL
Sbjct: 252 AKNLHLTEFVLSGSLPQETVVPASFNNGAFVGNFSELVFKFTLKREVGYYVMDYFLPSIL 311
Query: 366 IVVLSWVSFWIHREVGSGEIVIDDSEWEELIEEVGG 401
+V SWV+FW+ + + + + S I GG
Sbjct: 312 LVCTSWVTFWLQADASAPRVTLGTSTMLAFITLNGG 347
>UniRef50_UPI00015B49D8 Cluster: PREDICTED: similar to cys-loop
ligand-gated ion channel subunit; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to cys-loop
ligand-gated ion channel subunit - Nasonia vitripennis
Length = 513
Score = 104 bits (249), Expect = 7e-21
Identities = 62/212 (29%), Positives = 104/212 (49%), Gaps = 15/212 (7%)
Query: 188 LDMDYSMDCYFRQYWRDTRLSF--LGPIRSLSLSIKML-ERIWRPDTYFYNGKHSYVHTI 244
L D M FR + DTRL F + P ++ + + IW P Y N + S +
Sbjct: 94 LQFDVHMMLQFR--YLDTRLKFDDIAPHQNQIYGGQSAHDLIWTPSVYVANERSSVIMGN 151
Query: 245 TVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQ 304
+V + L+ I G ++ + RL C + L FP D Q CP++ S+ ++ Q ++ W
Sbjct: 152 SVKDLLISIDPSGMVVLNTRLEAILNCGLRLEKFPFDVQECPMVFESWTHNVQDMILNWD 211
Query: 305 NSQSVNFVPGMTLSQFDLI---------SFPYRNFTFTRREGDFSVLQVSFNLKRHTGYF 355
+ V + L+++ L+ S+ + G+FS + ++F L R G+F
Sbjct: 212 EAPIV-LADELHLTEYRLVEQWVNRSEVSYTTAQQHYGHFAGNFSSISITFKLAREMGFF 270
Query: 356 LIQVYVPCILIVVLSWVSFWIHREVGSGEIVI 387
++ Y+P ILIVV+SWVSFW+H + IV+
Sbjct: 271 MMDYYIPSILIVVISWVSFWLHVDASPPRIVL 302
>UniRef50_UPI0000D56CB6 Cluster: PREDICTED: similar to CG6927-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG6927-PA - Tribolium castaneum
Length = 464
Score = 103 bits (247), Expect = 1e-20
Identities = 56/191 (29%), Positives = 101/191 (52%), Gaps = 13/191 (6%)
Query: 204 DTRLSF--LGPIRSLSLSIKMLE-RIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDIL 260
D+ L F + P RSL L + L+ +IW P+ + + + + + L+ I + G ++
Sbjct: 92 DSNLKFEDISPKRSLILGDETLKAKIWTPNILLKDQEETTIVQVEKKEDLVSIDKTGLVI 151
Query: 261 YSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW-QNSQSVNFVPGMTLSQ 319
Y+ ++ K C M+L+ FP D Q C LI ++Y++ L+ +W + S+S+N + ++
Sbjct: 152 YTYKMVSKFYCWMDLKKFPFDTQKCTLIFSDWSYNSTNLLLEWNKKSESLNVSDNLHFTE 211
Query: 320 F--DLISF-------PYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLS 370
F D I PY+N + + G FS L + F R GY+L+ ++P L+V +
Sbjct: 212 FIVDEIKCDTGTNDGPYQNRDMSDQVGSFSELVIKFRFHRDIGYYLLDFFIPSYLLVCTA 271
Query: 371 WVSFWIHREVG 381
WV+FW+ + G
Sbjct: 272 WVTFWLQADAG 282
>UniRef50_P90876 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 618
Score = 103 bits (246), Expect = 2e-20
Identities = 72/314 (22%), Positives = 133/314 (42%), Gaps = 15/314 (4%)
Query: 88 PKILSAAKNTSRDTAEPDYWDNINEIMFSNYANSSFEQTDVFTWKQNKRSINDAVSKNI- 146
P +++ + ++ ++ Y + + F N +N + E + + + ++ +++N+
Sbjct: 180 PAACNSSNSDEKEISKQYYLEKYGDFSF-NVSNLNIELDKLHEMVHDFKPLDQIMNQNLG 238
Query: 147 ---------TSVLENLLK-NYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDC 196
+++L L K Y+ Q P+ V+ I ++SM MDY +D
Sbjct: 239 LDYQRPLPSSTILPFLRKMEYDARQPPSLHVDDTVTVKVGIAVQSMSNFELSTMDYDLDA 298
Query: 197 YFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQH 256
+ R W D RL L L+ IWRPD F N K+S H +T N L I
Sbjct: 299 WVRMSWIDPRLRHDLSRPILVNDYTFLKMIWRPDPIFTNSKYSTFHKVTYLNFYLFIFPD 358
Query: 257 GDILYSMRLTIK-AKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW--QNSQSVNFVP 313
G I MR+ +K + L +P D + L + S ++ + +W + ++
Sbjct: 359 GKIFMDMRVYLKPTAAQIVLCKYPHDNPAVSLKISSMGFTQDVVKLEWFSDTNDAIWIEK 418
Query: 314 GMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVS 373
+ + + + R+ G +S L+ F + R GY + Y+P + VV SW+S
Sbjct: 419 NVKIPELSIRHLHPDTCNGVRKSGVYSCLEAKFYMHREVGYHIANTYIPTAICVVFSWIS 478
Query: 374 FWIHREVGSGEIVI 387
W+ E G I +
Sbjct: 479 VWLPEEFVEGRIFV 492
>UniRef50_Q9VUV2 Cluster: CG33989-PD, isoform D; n=2; Drosophila
melanogaster|Rep: CG33989-PD, isoform D - Drosophila
melanogaster (Fruit fly)
Length = 737
Score = 99 bits (238), Expect = 1e-19
Identities = 70/250 (28%), Positives = 110/250 (44%), Gaps = 9/250 (3%)
Query: 143 SKNITSVLENLL--KNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQ 200
S + +L+ LL K Y+ LP G TV N+L+ S+ E + Y ++ Q
Sbjct: 334 SSSDKEILDLLLEKKRYDKRLLPPVN-GTLTV-NVNVLLLSLASPDESSLKYEVEFLLNQ 391
Query: 201 YWRDTRLSFLGPIRSLSLS-IKMLERIWRPDTYFYNGKHSYVHTITVPNKL-LRISQHGD 258
W D RL + L+ + + IW PDTYF H +P LRI ++G
Sbjct: 392 QWNDPRLQYGNKSHYDFLNALHHHDSIWTPDTYFI--MHGDFKDPIIPMHFALRIFRNGT 449
Query: 259 ILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQ-SVNFVPGMTL 317
I Y+MR + C L FP D C + S +Y Q+ Y W+N + ++ P +T
Sbjct: 450 ITYAMRRHLILSCQGSLHIFPFDDPKCSFSMESISYEEAQIKYVWKNDEDTLRKSPSLTT 509
Query: 318 SQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIH 377
LI G++S LQV R Y+ V++P I++V S+++FW+
Sbjct: 510 LNAYLIKNQTTACDQNSWRGNYSCLQVELTFTRDRAYYFTTVFIPGIILVTSSFITFWLE 569
Query: 378 REVGSGEIVI 387
++I
Sbjct: 570 WNAVPARVMI 579
>UniRef50_Q0GQQ4 Cluster: Cys-loop ligand-gated ion channel subunit;
n=2; Apis mellifera|Rep: Cys-loop ligand-gated ion
channel subunit - Apis mellifera (Honeybee)
Length = 469
Score = 98.7 bits (235), Expect = 3e-19
Identities = 63/212 (29%), Positives = 102/212 (48%), Gaps = 15/212 (7%)
Query: 188 LDMDYSMDCYFRQYWRDTRLSF--LGPIRSLSLSIKML-ERIWRPDTYFYNGKHSYVHTI 244
L D M FR + D RL F + P + + + + IW P Y N S +
Sbjct: 58 LQFDVHMMLQFR--YLDARLKFSNIAPYLNQIYGGQFVRDLIWTPTVYVSNEPSSAITGN 115
Query: 245 TVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQ 304
V + L+ I G + + RL C + L FP D Q CPLI S+ ++ +V W
Sbjct: 116 NVKDVLVSIDPSGMVRLNTRLQATLNCGLRLEKFPFDVQECPLIFESWTHNVLDMVLYW- 174
Query: 305 NSQSVNFVPGMTLSQFDLISFPYRN---FTFTRRE------GDFSVLQVSFNLKRHTGYF 355
+ + + + L+++ L+ + F T ++ G+FS + ++F L R G+F
Sbjct: 175 DQEPIILADELHLTEYKLVEKWVNSSEIFYTTSQQYYGHFAGNFSSISITFKLAREMGFF 234
Query: 356 LIQVYVPCILIVVLSWVSFWIHREVGSGEIVI 387
++ Y+P ILIVV+SWVSFW+H + IV+
Sbjct: 235 MMDYYIPSILIVVISWVSFWLHMDASPPRIVL 266
>UniRef50_Q9W4G1 Cluster: CG6927-PA; n=6; Diptera|Rep: CG6927-PA -
Drosophila melanogaster (Fruit fly)
Length = 524
Score = 97.1 bits (231), Expect = 1e-18
Identities = 67/274 (24%), Positives = 127/274 (46%), Gaps = 21/274 (7%)
Query: 137 SINDAVSKNITSVLENLLKN--YENSQLP-TH---GKGYPTVVQTNILIRSMGPVSELDM 190
+++D S + T +L+ L Y+ + P T+ G+ P V I M + D+
Sbjct: 27 TLDDGDSLSQTQLLDRLTHGCRYDRLERPITYSETGQRLPVDVYMRAYIYFMQNLEAHDL 86
Query: 191 DYSMDCYFRQYWRDTRLSF--LGPIRSLSL--SIKMLERIWRPDTYFYNGKHSYVHTITV 246
+ + + + D RL+F + P R + + +W P + N + S + +T
Sbjct: 87 QFKIYALLQMRYLDPRLNFRNVSPKRRQPILGEEHLRNSLWMPHIFLANERDSSILGLTE 146
Query: 247 PNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNS 306
+ L IS G ++ S R+ C + L+ FP D Q C +L S+ Y+ +LV W+
Sbjct: 147 KDILTSISPDGTVIVSNRIKATLYCWLNLKKFPFDEQHCSTVLESWMYNTSELVLHWEQK 206
Query: 307 QSVNFVPGMTLSQFDLISFPYRNFTFTRRE----------GDFSVLQVSFNLKRHTGYFL 356
+ + + + L++F ++ + N T + G++S L + +L R G++L
Sbjct: 207 RPITYDGALHLTEF-VLQRSWSNETVINADLSDLRHGAFAGNYSSLSFTVHLTRVVGFYL 265
Query: 357 IQVYVPCILIVVLSWVSFWIHREVGSGEIVIDDS 390
+ ++P +LIV +SWVSFW+ + I + S
Sbjct: 266 MDYFLPSMLIVAISWVSFWLQADQAPPRITLGTS 299
>UniRef50_Q2PDY9 Cluster: CG33989-PF, isoform F; n=16;
Endopterygota|Rep: CG33989-PF, isoform F - Drosophila
melanogaster (Fruit fly)
Length = 779
Score = 97.1 bits (231), Expect = 1e-18
Identities = 62/222 (27%), Positives = 102/222 (45%), Gaps = 7/222 (3%)
Query: 158 ENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLS 217
+N++ P H +G TV N+L+ S+ E + Y ++ Q W D RL +
Sbjct: 376 QNARRP-HNRGTLTV-NVNVLLLSLASPDESSLKYEVEFLLNQQWNDPRLQYGNKSHYDF 433
Query: 218 LS-IKMLERIWRPDTYFYNGKHSYVHTITVPNKL-LRISQHGDILYSMRLTIKAKCPMEL 275
L+ + + IW PDTYF H +P LRI ++G I Y+MR + C L
Sbjct: 434 LNALHHHDSIWTPDTYFI--MHGDFKDPIIPMHFALRIFRNGTITYAMRRHLILSCQGSL 491
Query: 276 RNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQ-SVNFVPGMTLSQFDLISFPYRNFTFTR 334
FP D C + S +Y Q+ Y W+N + ++ P +T LI
Sbjct: 492 HIFPFDDPKCSFSMESISYEEAQIKYVWKNDEDTLRKSPSLTTLNAYLIKNQTTACDQNS 551
Query: 335 REGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
G++S L+V R ++ V++P I++V S+++FW+
Sbjct: 552 WRGNYSCLRVDLIFTRDRAFYFTTVFIPGIILVTSSFITFWL 593
>UniRef50_Q9V9Y4 Cluster: CG11340-PA; n=2; Sophophora|Rep:
CG11340-PA - Drosophila melanogaster (Fruit fly)
Length = 526
Score = 96.7 bits (230), Expect = 1e-18
Identities = 58/227 (25%), Positives = 107/227 (47%), Gaps = 13/227 (5%)
Query: 166 GKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSI----K 221
G+ P + I M + D+ +++ + + D RL+F + + I +
Sbjct: 98 GEEVPMDIYARFYIYVMKNLDSSDLQFTVQGLLQLRYLDPRLAFSSYLPNRRQPIMGESE 157
Query: 222 MLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMD 281
+ + +W P + N + S V + ++L I +G +L S RL C M + FP D
Sbjct: 158 LKKMLWVPHIFLTNEQASTVLGTSAKDELTSIYPNGTVLTSTRLQATLYCWMNFQKFPFD 217
Query: 282 RQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYR------NFTFTRR 335
Q C L S+ Y+ + W+ V+F + L++++LI Y N ++
Sbjct: 218 EQKCKTTLESWMYNTTLVQLHWETDNPVSFDKQLQLTEYNLIGSLYNESIRVSNESYMSH 277
Query: 336 ---EGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
EG++S++ + L R GY++I ++P I+IV +SWVSFW+ +
Sbjct: 278 GSLEGNYSIISFTVLLTREVGYYVIDYFLPSIMIVTISWVSFWLQAD 324
>UniRef50_A7SDE9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 299
Score = 95.1 bits (226), Expect = 4e-18
Identities = 48/128 (37%), Positives = 70/128 (54%), Gaps = 2/128 (1%)
Query: 168 GYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIW 227
G P VV +I + S G + E +M+Y YFRQ+W+D RL+ S+ L + R+W
Sbjct: 1 GPPVVVDLSIYVSSFGNIEEANMEYKFFGYFRQFWKDERLANRVN-HSVILKGDEISRMW 59
Query: 228 RPDTYFYNGKHSYVHTITVP-NKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCP 286
RPD + YN + S + N ++ I +GD++YS I A+C + L FPMD Q C
Sbjct: 60 RPDPFCYNARKSSLTDADADINSMVTIHPNGDVVYSRMTIITAECELNLHKFPMDEQKCH 119
Query: 287 LILGSYAY 294
L +GS Y
Sbjct: 120 LKIGSCEY 127
Score = 63.3 bits (147), Expect = 2e-08
Identities = 31/88 (35%), Positives = 50/88 (56%), Gaps = 1/88 (1%)
Query: 293 AYSNQQLVYQWQNSQSVNF-VPGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRH 351
+Y+ Q + Y+W+ + + V L+QF L S + G+ + + V F +R
Sbjct: 159 SYTTQDIKYRWRPPMNSSVDVRSRNLAQFALTSIIEVEYVEHYDLGNQNRMCVCFTFQRR 218
Query: 352 TGYFLIQVYVPCILIVVLSWVSFWIHRE 379
GYFLIQVY+P I +VVLSW+ FW+ ++
Sbjct: 219 LGYFLIQVYIPSIFVVVLSWIVFWMDKD 246
>UniRef50_UPI00015ADFAB Cluster: hypothetical protein
NEMVEDRAFT_v1g9118; n=1; Nematostella vectensis|Rep:
hypothetical protein NEMVEDRAFT_v1g9118 - Nematostella
vectensis
Length = 135
Score = 94.3 bits (224), Expect = 7e-18
Identities = 48/139 (34%), Positives = 75/139 (53%), Gaps = 5/139 (3%)
Query: 191 DYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKL 250
D+++D + RQ W D RL G R +L+ IW PDT+ N K +Y H + N
Sbjct: 2 DFTLDLFLRQVWSDPRLRH-GEPRHHTLTGTDKHLIWLPDTFILNVKEAYHHHVPSDNSQ 60
Query: 251 LRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVN 310
+ I GD++YS+ + A C M+L ++P+D Q+C L + SYA+ + +LVY+W V
Sbjct: 61 VAIEADGDVMYSIGMRATAGCEMDLSSYPLDTQTCQLRIMSYAHVSAELVYKWGEEGRV- 119
Query: 311 FVPGMTLSQFDLISFPYRN 329
GM++ D+ F N
Sbjct: 120 ---GMSILNTDMAEFEVTN 135
>UniRef50_Q61R47 Cluster: Putative uncharacterized protein CBG06736;
n=1; Caenorhabditis briggsae|Rep: Putative
uncharacterized protein CBG06736 - Caenorhabditis
briggsae
Length = 394
Score = 88.6 bits (210), Expect = 4e-16
Identities = 51/160 (31%), Positives = 83/160 (51%), Gaps = 5/160 (3%)
Query: 145 NITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 204
N ++ LL E S+ KG TV I+ + +SE+ D+ M+ Y + W D
Sbjct: 24 NEARLMSKLLTEREYSKHKIPKKGGITV-SVEFWIQEISSISEMTNDFEMEIYINEMWTD 82
Query: 205 TRLSF--LGPIRS-LSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILY 261
L F LG ++ L+L + L ++W+P+T F N K + ++ N L + +G +
Sbjct: 83 PNLKFSHLGACKANLTLYEQTLNKLWKPNTCFVNSKFAEIYESPFQNVFLTLFDNGTVWV 142
Query: 262 SMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVY 301
+ RL +K C MEL NFPMD Q+C L S+ Y++ +V+
Sbjct: 143 NYRLRVKGPCEMELTNFPMDTQACRLNYQSF-YNSTLIVF 181
Score = 42.3 bits (95), Expect = 0.031
Identities = 27/120 (22%), Positives = 57/120 (47%), Gaps = 6/120 (5%)
Query: 259 ILYSMRLTIKAKCPMELRNFPMDRQSC---PLILGSYAYSNQQLVYQWQNSQSVNF-VPG 314
I++S L +K P + F + +Q L +++Y+N+++ QW + + F +
Sbjct: 179 IVFSEMLLLKFALPFLI--FRLTKQMMLKNSLFFLNFSYNNEEVRLQWNSQRKPVFAIQP 236
Query: 315 MTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSF 374
+ L+ F L + G + L V+F +R ++ +Q Y+P + +SW++F
Sbjct: 237 IRLADFTLKDITTGTISRDYPAGKWDELIVTFVFERRYMWYFLQAYLPTFFSIFISWIAF 296
>UniRef50_Q17KW1 Cluster: Glycine receptor beta, putative; n=1;
Aedes aegypti|Rep: Glycine receptor beta, putative -
Aedes aegypti (Yellowfever mosquito)
Length = 439
Score = 83.8 bits (198), Expect = 1e-14
Identities = 59/228 (25%), Positives = 105/228 (46%), Gaps = 11/228 (4%)
Query: 171 TVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLS---LSIKMLER-- 225
T V ++ I + V E + S+D + + W D RL P +++ + + E+
Sbjct: 11 TEVSISLYINRISGVDENKEEISIDAFLQVTWEDPRLVPDDPTGTMTKEYMELTPTEQMT 70
Query: 226 IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSC 285
+W PD Y + V T+ LR+ ++ ++ + TI KC M+ +P+D Q C
Sbjct: 71 VWVPDLYIRQLREMKVMTLFEEISKLRLYKNSTLVLTKGATIIFKCDMDFVLYPLDVQRC 130
Query: 286 PLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDL----ISF--PYRNFTFTRREGDF 339
P+ SY YS +++ ++W+N + F F L +SF T E +
Sbjct: 131 PVDFSSYKYSVREMRFRWKNDNGLIFPKDFGDGFFRLPKYVVSFYTEQNPQTIHYGEDNH 190
Query: 340 SVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVI 387
S ++ L R +L++ Y+P L V +SW SF + E+ G +V+
Sbjct: 191 SSARLEITLSREVKSYLLENYLPSTLFVSMSWGSFVVVPEIVPGRMVL 238
>UniRef50_Q6Q069 Cluster: Neuronal nicotinic acetylcholine Apisa7-2
subunit; n=3; Apis mellifera|Rep: Neuronal nicotinic
acetylcholine Apisa7-2 subunit - Apis mellifera
(Honeybee)
Length = 461
Score = 82.6 bits (195), Expect = 2e-14
Identities = 51/232 (21%), Positives = 99/232 (42%), Gaps = 5/232 (2%)
Query: 153 LLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF-LG 211
LL Y+ P P V + + + V E + + +C+ Q W D L +
Sbjct: 13 LLDGYDAGVRPAENSSQPLAVVFGLSLHHIIDVDEKNQILTTNCWVTQIWTDHHLKWNAS 72
Query: 212 PIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKC 271
+ + R+WRPDT YN + + ++ +S G++++ ++ C
Sbjct: 73 EFAGIRVIRVPYNRVWRPDTILYNNADPQYSSAVINTNVI-VSHTGEVVWLSHGIFRSSC 131
Query: 272 PMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRNFT 331
+++ FP D Q C L S+ Y QL + Q+ Q + +FDL++F R
Sbjct: 132 DIDVEFFPFDEQRCVLKWASWTYDGYQLELEKQSEQG-DVSNYQANGEFDLVNFSARRNV 190
Query: 332 --FTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
++ + + L+R +++ + +PCILI ++ + F++ E G
Sbjct: 191 EYYSCCPEPYPDITYEIRLRRRPMFYVFNLILPCILINSVALLVFYVPSESG 242
>UniRef50_UPI0000D55E50 Cluster: PREDICTED: similar to AcetylCholine
Receptor family member (acr-21); n=3; Endopterygota|Rep:
PREDICTED: similar to AcetylCholine Receptor family
member (acr-21) - Tribolium castaneum
Length = 649
Score = 82.2 bits (194), Expect = 3e-14
Identities = 56/243 (23%), Positives = 106/243 (43%), Gaps = 9/243 (3%)
Query: 144 KNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWR 203
+N ++ +L+ NY+ + P P V I + + V E + + +C+ Q W
Sbjct: 18 ENEARLMRHLMTNYDAAVRPVENSSLPLTVIFGISLHHIIDVDEKNQILTTNCWITQAWI 77
Query: 204 DTRLSF-LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYS 262
D L + + + R+WRPD YN + + ++ +S G++L+
Sbjct: 78 DHHLRWNASDFAGIKVIRIPYTRVWRPDLILYNNADPQFQSSVINTNVI-VSSSGEVLWL 136
Query: 263 MRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQ--LVYQWQNSQSVNFVPGMTLSQF 320
++ C + + FP D QSC + S+ Y Q L Q + N+ +F
Sbjct: 137 SHGIYRSSCDINVEYFPFDLQSCHMKWASWTYDGYQVELAKQTEEGDVSNY---QANGEF 193
Query: 321 DLISF-PYRNFTF-TRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHR 378
DLISF ++ F + + + + LKR +++ + +PCILI ++ + F++
Sbjct: 194 DLISFSSVKHIEFYSCCPEPYPDITYTIKLKRRPLFYVFNLILPCILINGIALLVFYVPS 253
Query: 379 EVG 381
E G
Sbjct: 254 ESG 256
>UniRef50_Q2XWK6 Cluster: Nicotinic acetylcholine receptor subunit
type G; n=1; Lymnaea stagnalis|Rep: Nicotinic
acetylcholine receptor subunit type G - Lymnaea
stagnalis (Great pond snail)
Length = 618
Score = 82.2 bits (194), Expect = 3e-14
Identities = 53/237 (22%), Positives = 105/237 (44%), Gaps = 8/237 (3%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
++E LL Y P V+ + + + + E++ +++ + Q W D RL+
Sbjct: 91 LMERLLARYHRYSRPVMNASLSVQVKFGLTLVQISDMDEVNQVLTINVWLEQEWVDERLT 150
Query: 209 FLGPIRSLSLSIKML--ERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLT 266
+ P +L I + E++W PD YN Y T N + +G + +
Sbjct: 151 W-SPKEYNNLHILRIPCEKLWLPDIVLYNSADDY--TTGYMNSKAMVQHNGTVFWPPPAK 207
Query: 267 IKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFP 326
++ C +++ FP D Q+C L GS+ Y Q V S +V+ + +++L+
Sbjct: 208 FRSSCKIDITYFPFDDQTCELKFGSWTYDGFQ-VDITNRSATVDLQNYVFSGEWELMDVR 266
Query: 327 YR--NFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
R T+ + ++ + ++R T Y+L + PC+ + +LS + FW+ + G
Sbjct: 267 IRRTEVTYACCIEPYPDVRFTIVIRRKTLYYLFNIIFPCLWLTILSLLGFWLPPDSG 323
>UniRef50_A7NAE6 Cluster: Neurotransmitter-gated ion-channel ligand
binding domain protein; n=10; Francisella
tularensis|Rep: Neurotransmitter-gated ion-channel
ligand binding domain protein - Francisella tularensis
subsp. holarctica FTA
Length = 351
Score = 80.2 bits (189), Expect = 1e-13
Identities = 57/233 (24%), Positives = 115/233 (49%), Gaps = 17/233 (7%)
Query: 170 PTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRP 229
PT+++T+ I + + E++ +D FR W D RL F K+ + ++
Sbjct: 32 PTLIKTSAFITDIQSLDEMNEQLQIDVIFRFSWNDQRLEF--DKNEEKTPYKLYQGDFQY 89
Query: 230 DTYFYNGKH--SYVHTITVPN---KLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQS 284
D F K S ++ I P + ++I +GDI+Y+ + T+ + PM L FP D+Q+
Sbjct: 90 DEVFEGWKPQISIINEIGTPQIKARQIKIYPNGDIIYTEQRTLHLETPMRLEKFPFDKQT 149
Query: 285 CPLILGSYAYSNQ--QLVYQWQNSQSV-NFV---PGMTLSQFDLISFPYRNFT----FTR 334
+ + Y+++ QL+ + + +V ++V P + ++++ L +F +N +
Sbjct: 150 LKTYIIPFGYNSKEVQLIVEPNHKITVKDYVKDHPNINVAEWHLSNFDLKNIEPIKYYYG 209
Query: 335 REGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVI 387
+ S+L+ S +L+R L++V +P L+V+ W FW+ + S + I
Sbjct: 210 KPQRISMLEFSISLERKPTNILLKVLIPLTLLVLAMWAIFWMDTKALSDRLNI 262
>UniRef50_A7RS32 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 325
Score = 79.8 bits (188), Expect = 2e-13
Identities = 62/251 (24%), Positives = 115/251 (45%), Gaps = 12/251 (4%)
Query: 140 DAVSKNITSVLE-NLLKNYENSQLP--THGKGYPTVVQTNILIRSMGPVSELDMDYSMDC 196
D + LE +L + Y LP T KG P V+ ++ + + V++ ++
Sbjct: 6 DTKRTEVVQKLEMDLFRTYNKDVLPKETLDKGVP--VRLDLALNQIIDVNKRAQTMTVVI 63
Query: 197 YFRQYWRDTRLSF-LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQ 255
+ RQYWRD RL + + + + R+W PD YN L I+
Sbjct: 64 WVRQYWRDPRLRWNVSAYDGVDNIVIKASRLWLPDITLYNNARDDYKLDKESQHSLTITS 123
Query: 256 HGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGM 315
G + K+ C + +R+FP D Q+C L LGS++Y+ ++ + +N +
Sbjct: 124 RGGVSRFFPTIYKSSCALNIRHFPFDDQTCILKLGSWSYNVFEVNLTNVGNGDLNSF--I 181
Query: 316 TLSQFDLISFPY-RNFT-FTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVS 373
+ ++ L P R+ T F + L N++R + Y++I + PC++++ L+++
Sbjct: 182 SNGEWVLKGMPAERHETKFRCCPHPYIFLLYKINIRRRSLYYVINCFTPCLIMLALTFLG 241
Query: 374 FWIHREVGSGE 384
F++ GSGE
Sbjct: 242 FYL--PSGSGE 250
>UniRef50_Q4RIA9 Cluster: Chromosome 8 SCAF15044, whole genome
shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 8
SCAF15044, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 549
Score = 77.0 bits (181), Expect = 1e-12
Identities = 55/240 (22%), Positives = 111/240 (46%), Gaps = 15/240 (6%)
Query: 149 VLENLLK--NYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTR 206
++E+LL +Y P VQ + + + V E + + + + Q W+D R
Sbjct: 6 LVEHLLNPAHYNKLIRPATNGSELVTVQLMVSLAQLISVHEREQVMTTNVWLTQEWQDYR 65
Query: 207 LSFLGPIRSLSLSIKMLER-IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRL 265
L+++ L +++ + IW PD YN N + +S G I +
Sbjct: 66 LTWIPEEFDGMLKVRLPSKHIWLPDVVLYNNADGVYEVSFYSNAV--VSYDGSIFWLPPA 123
Query: 266 TIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQ--LVYQWQNSQSVNFVPGMTLSQFDLI 323
K+ C +E+++FP D+Q+C L S+ Y + LV + + +F P ++D+I
Sbjct: 124 IYKSACKIEVKHFPFDQQNCTLRFRSWTYDRTEIDLVLRADVASMDDFTPS---GEWDII 180
Query: 324 SFPYRNFTFTRREGDFSVLQVSFN--LKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ P R GD + + ++++ ++R ++ I + +PC+LI L+ + F++ + G
Sbjct: 181 ALPGRR---NENPGDPTYVDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSDCG 237
>UniRef50_A7S2P0 Cluster: Predicted protein; n=4; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 541
Score = 76.2 bits (179), Expect = 2e-12
Identities = 58/251 (23%), Positives = 113/251 (45%), Gaps = 16/251 (6%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L ++ +Y+N P K + V+ + + + V E S+ Y RQ W + ++
Sbjct: 72 LLADVFGSYDNKLRPVLSKTHNVTVKLGLTLNQIMDVIEKFELLSVSLYVRQKWENPLVA 131
Query: 209 F----LGPIRSLSLSIKMLERIWRPDTYFYNGKHS-YVHTITVPNKLLRISQHGDILYSM 263
+ G I ++L L W+PD Y YN S Y ++ ++++ G +
Sbjct: 132 WNKSEYGGIVQVNLDPSTL---WKPDIYLYNNADSGYDGSLYGFTAKIKVNYSGTNTWLA 188
Query: 264 RLTIKAKCPMELRNFPMDRQSCPLILGSYAY-SNQQLVYQWQNSQSVNFVPGMTLSQFDL 322
C + ++ FP D+Q C L GS+ Y +N ++ ++ S+ ++D
Sbjct: 189 PKIFTTSCKINVKYFPFDQQECRLKFGSWTYDANSVDIFPEEDQASIKGY--QKNGEWDF 246
Query: 323 ISFPYRNFTFTRR---EGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
I FP + + F+ + + ++R T Y+ + + +PC+LI VLS +SF + +
Sbjct: 247 IGFPCKRSILYYPCCPDSPFTDVTCTLIIRRKTLYYWVNLIIPCMLITVLSLLSFIVSTD 306
Query: 380 VGS--GEIVID 388
G G ++ D
Sbjct: 307 SGERVGLVITD 317
>UniRef50_Q7T2R4 Cluster: Nicotinic acetylcholine receptor alpha 9d
subunit; n=7; Clupeocephala|Rep: Nicotinic acetylcholine
receptor alpha 9d subunit - Fugu rubripes (Japanese
pufferfish) (Takifugu rubripes)
Length = 521
Score = 75.4 bits (177), Expect = 4e-12
Identities = 49/238 (20%), Positives = 106/238 (44%), Gaps = 10/238 (4%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
++ +L NY N+ P + V I + + + E + + + RQ W D L+
Sbjct: 12 LMTDLFSNYTNALRPVEDTDHIINVTLQITLSQIIDMDERNQILTTYLWVRQVWMDAYLT 71
Query: 209 FLGPIRSLSLSIKMLER-IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
+ +I++ +WRPD YN + N +LR G +++
Sbjct: 72 WKKEDYDGLDTIRIPSSYVWRPDIVLYNSADDEFSSSMETNVVLR--HDGQVMWDQPAIT 129
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQ--LVYQWQNSQSVNFVPGMTLSQFDLISF 325
K+ C +++ +FP D Q C L GS+ ++ Q L ++ +FVP + +++++
Sbjct: 130 KSSCSVDVAHFPFDLQECHLTFGSWTHNGNQMDLFNALDSADLADFVPNV---EWEVLGM 186
Query: 326 PYRN--FTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
P + + + + + +LKR +++ + +PC++I L+ + F++ + G
Sbjct: 187 PAKKNVILYGCCSDPYPDITFTLHLKRRASFYIFNLLIPCMMISFLAPLGFYLPADSG 244
>UniRef50_Q5BW84 Cluster: SJCHGC08361 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC08361 protein - Schistosoma
japonicum (Blood fluke)
Length = 213
Score = 75.4 bits (177), Expect = 4e-12
Identities = 42/164 (25%), Positives = 83/164 (50%), Gaps = 9/164 (5%)
Query: 150 LENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF 209
++ L+KNYE+S P V+ +I ++ +G ++E + + + Q W D L +
Sbjct: 16 IDTLMKNYESSVRPLKNISEKLTVKISIRLQQIGGLNERNQVLTTILFLEQIWEDDYLKW 75
Query: 210 ----LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRL 265
G +R+L + K ++W PDTY +N + ++ + + I G + + + +
Sbjct: 76 NESEFGNVRTLRIPAK---QVWTPDTYVFNNA-DHTNSGFLEGIYVIIHSSGKVSWPIPV 131
Query: 266 TIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQ-NSQS 308
+K C +++ FP D Q+C + GS+ Y + + Y++Q N QS
Sbjct: 132 QLKTSCKVDITLFPFDHQNCEIQFGSWMYKSDWIEYKFQMNPQS 175
>UniRef50_A7SW63 Cluster: Predicted protein; n=3; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 324
Score = 74.5 bits (175), Expect = 6e-12
Identities = 52/238 (21%), Positives = 114/238 (47%), Gaps = 14/238 (5%)
Query: 148 SVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRL 207
++L+ LL+NY P P ++ I++R + ++E D +++ + RQYW+D L
Sbjct: 3 ALLKYLLQNYSKDARPVLNVNDPVQLKLGIMLRQVIDLNERDQILTINVWIRQYWKDHLL 62
Query: 208 SF----LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKL---LRISQHGDIL 260
+ G I+S++++ +R+W+PD YN + + ++ NK+ + ++ G
Sbjct: 63 KWNPDDFGGIKSINIA---PDRVWKPDVLLYN--RTDLRFGSLNNKIDTNVIVNHDGSTT 117
Query: 261 YSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQF 320
+ IK++C +++R FP D QSC L GS+ + ++ + ++ ++
Sbjct: 118 WLAPAIIKSECKIDVRFFPFDVQSCELTFGSWTHDGLKIDIHLKQESGIDTENFSDNREW 177
Query: 321 DLISFPYRNFT--FTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
L R + + + + L+R +++ + +P +I +LS SF++
Sbjct: 178 FLKGTSGRRDVKMYICCPEPYPTVTYTIILRRRAMFYVFNMVLPTGVIALLSLFSFYL 235
>UniRef50_Q6F6K3 Cluster: Acetylcholine receptor protein 17, isoform
b; n=4; Caenorhabditis|Rep: Acetylcholine receptor
protein 17, isoform b - Caenorhabditis elegans
Length = 515
Score = 73.3 bits (172), Expect = 1e-11
Identities = 56/256 (21%), Positives = 115/256 (44%), Gaps = 30/256 (11%)
Query: 149 VLENLLKNYENSQLPTHGKGY-PTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRL 207
+++ L ++Y P + PT V + + + V E D ++ C+ +YW+D L
Sbjct: 27 LIKYLFRDYHKELRPVKDESSGPTNVTVQLYFKQIQKVHENDQIITLYCWIEEYWQDEFL 86
Query: 208 SF----LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSM 263
++ G I+SL + +M IW+PD YN + + + + +I G I
Sbjct: 87 TWNPSDFGNIKSLHVPSEM---IWKPDLLVYNNANMNIKENEMQTNV-QIEHTGKISLFR 142
Query: 264 RLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW-----------QNSQSV--- 309
+ C +++ FP D+Q C ++L S++Y Q++ +N+ ++
Sbjct: 143 AIITDITCDLQMEKFPYDQQICFIMLASWSYDGSQIMLNTAEQPTEAPLDIKNTTNLAIL 202
Query: 310 -NFVPGMTLSQFDLISFPYRNFT--FTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILI 366
+++P M ++ L+ F YRN + + + F +KR+ Y+L + +P I
Sbjct: 203 NHYIPNM---EWKLVDFRYRNNLKYYDCCPNPYPDISYFFAIKRNPSYYLFTLIIPSAFI 259
Query: 367 VVLSWVSFWI-HREVG 381
+++ + F+ H G
Sbjct: 260 TIVTVIGFFTPHSSTG 275
>UniRef50_Q2XWK4 Cluster: Nicotinic acetylcholine receptor subunit
type I; n=1; Lymnaea stagnalis|Rep: Nicotinic
acetylcholine receptor subunit type I - Lymnaea
stagnalis (Great pond snail)
Length = 527
Score = 73.3 bits (172), Expect = 1e-11
Identities = 58/239 (24%), Positives = 105/239 (43%), Gaps = 12/239 (5%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYS-----MDCYFRQYWR 203
++ +LLK YE G+ ++ + + LD+D S ++R W
Sbjct: 62 LISSLLKKYERQG--KQGRPVINTSDNMTVLFGLSLIQILDVDESNQVLKASMWYRYEWN 119
Query: 204 DTRLSFLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYS 262
D L + + SI++ IW PD YN + + L + +GDI +
Sbjct: 120 DMLLKWDPAMHDDIQSIRIPSSMIWLPDILLYNFADDRLREQR--DALCIVQNNGDIQWM 177
Query: 263 MRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDL 322
+ +++ C + + FP D QSC L GS+ Y+ +L ++ S + + +++D+
Sbjct: 178 PQAILRSSCSFDTKYFPFDVQSCWLKFGSWTYNGFKLNVEFVREHSFDLSDYVMSNEWDI 237
Query: 323 I-SFPYRNFT-FTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
I + RN +T F L LKR T ++ + +PC L+ +L+ V FW+ E
Sbjct: 238 IENRAVRNVKYYTCCPEPFPDLTFHLTLKRKTAFYTFILILPCTLLSLLTLVIFWVPPE 296
>UniRef50_A7S3F7 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 334
Score = 73.3 bits (172), Expect = 1e-11
Identities = 58/240 (24%), Positives = 112/240 (46%), Gaps = 13/240 (5%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
++ +LL Y P + ++ I ++ + V E + Q W DTRL+
Sbjct: 7 LIHDLLDTYNPRARPVTNDNHTVGLKLTIRLQQIMDVDEKNEVIQTFLILEQMWNDTRLA 66
Query: 209 F----LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
+ G I+ ++L K+ IW PD N + + + N L I+ G++L+
Sbjct: 67 WNETEYGGIKQMTLRSKL---IWTPDISVLNSANKDMD-LREKNIRLFINSAGEVLWMNP 122
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQL-VYQWQNSQSVNFVPGMTLSQFDLI 323
L + C M++ +FP D Q+C L GS++ S + + V+ ++++ ++ + + ++ L
Sbjct: 123 LILHTSCGMDIAHFPFDNQACELRFGSWSTSLRYMDVHPFEDTANLQYF--VENGEWILE 180
Query: 324 S-FPYRNF-TFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
S YR + E +F + L R T ++ + +PC+LI VL+ + F + E G
Sbjct: 181 STTSYRKLKKYGCCESEFPEVTYVLELHRRTLFYTMNFILPCVLIAVLALLVFLLPPESG 240
>UniRef50_P36544 Cluster: Neuronal acetylcholine receptor subunit
alpha-7 precursor; n=65; Euteleostomi|Rep: Neuronal
acetylcholine receptor subunit alpha-7 precursor - Homo
sapiens (Human)
Length = 502
Score = 73.3 bits (172), Expect = 1e-11
Identities = 52/234 (22%), Positives = 101/234 (43%), Gaps = 8/234 (3%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL 210
+ L+KNY + P P V ++ + + V E + + + + + W D L +
Sbjct: 31 KELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWN 90
Query: 211 GPIRSLSLSIKMLE-RIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKA 269
+++ + +IW+PD YN N L+ S H Y K+
Sbjct: 91 VSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQ--YLPPGIFKS 148
Query: 270 KCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRN 329
C +++R FP D Q C L GS++Y L Q Q + ++P ++DL+ P +
Sbjct: 149 SCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPN---GEWDLVGIPGKR 205
Query: 330 FT--FTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ + + + + ++R T Y+ + + +PC+LI L+ + F + + G
Sbjct: 206 SERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSG 259
>UniRef50_A7SI11 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 404
Score = 71.7 bits (168), Expect = 4e-11
Identities = 58/248 (23%), Positives = 112/248 (45%), Gaps = 16/248 (6%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
++ +LL Y +SQ P PTV+ I ++ + ++ + Q W D +L
Sbjct: 5 LVTDLLAGYHDSQRPALDNNEPTVINFTIRLQQIYELNGQLQKMVSSVWIEQAWWDHKLQ 64
Query: 209 F----LGPIRSLSLSIKMLERIWRPDTYFYNG--KHSYVHTITVPNKLLRISQHGDILYS 262
+ G I+ + L + + IW PD N K S + N +L + +G + +
Sbjct: 65 WDQSKYGGIKEVVLPERGV--IWVPDVVLLNNAEKSSMGKPVNEGNPVL-VESNGVVRWL 121
Query: 263 MRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQL-VYQWQNSQSVNFVPGMTLSQFD 321
+ +K++C M++R++P D Q C L S+ S +L + N N+ S++D
Sbjct: 122 APVVLKSRCKMDVRSYPFDEQYCGLKFASWTGSQSELRLDAMDNDVRQNYSES---SEWD 178
Query: 322 LI-SFPYRNFTFTRREG--DFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHR 378
L+ ++ R+ S ++ +KRH Y+++ + PC+L +L+ + F +
Sbjct: 179 LLQTYTLRSSAKATHSSPEKKSAIRYVIRIKRHVFYYIVYLLAPCLLTSLLAILLFTLPP 238
Query: 379 EVGSGEIV 386
E G +V
Sbjct: 239 ESGERMVV 246
>UniRef50_UPI0000E47621 Cluster: PREDICTED: similar to nicotinic
acetylcholine receptor subunit type G, partial; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
nicotinic acetylcholine receptor subunit type G, partial
- Strongylocentrotus purpuratus
Length = 283
Score = 70.9 bits (166), Expect = 8e-11
Identities = 54/207 (26%), Positives = 98/207 (47%), Gaps = 9/207 (4%)
Query: 173 VQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLS-IKM-LERIWRPD 230
V+ ++ I ++ + E + + + + Q W D L + P S +++ +++ + IWRPD
Sbjct: 40 VKIDLAIVNLLDMDEANQIMTANTFMTQEWNDAFLQW-EPSESWNITDVQVPINNIWRPD 98
Query: 231 TYFYNGKHSYVHT-ITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLIL 289
+N + ++ I + +R G + + + + CPM FP D Q+C L L
Sbjct: 99 IILHNNANDELNGGIRWTHAWIRYD--GTVTWKTNYILMSACPMNPLYFPFDTQNCSLKL 156
Query: 290 GSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFN-- 347
GS+ Y N+ + NS S + ++DLI FP R R+ + V FN
Sbjct: 157 GSWTY-NEDEINVIANSTSGDATQYQPNGEWDLIDFPLRREVDVRQCCPGAYPSVIFNVI 215
Query: 348 LKRHTGYFLIQVYVPCILIVVLSWVSF 374
+KR ++ + VPC++I L +SF
Sbjct: 216 IKRQFLFYFFNLVVPCVIISSLVLLSF 242
>UniRef50_Q4BXY7 Cluster: Neurotransmitter-gated ion-channel
ligand-binding; n=2; Chroococcales|Rep:
Neurotransmitter-gated ion-channel ligand-binding -
Crocosphaera watsonii
Length = 340
Score = 70.9 bits (166), Expect = 8e-11
Identities = 45/209 (21%), Positives = 97/209 (46%), Gaps = 9/209 (4%)
Query: 171 TVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPD 230
T + I + ++E++ +D Y W D+R +LS + LE +W+P+
Sbjct: 39 TQILVGIYTLDLAKINEVEQTVYIDFYLGLQWYDSRFDSALSNTNLSPYQRKLEEVWQPN 98
Query: 231 TYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILG 290
+ N ++ ++++ I+ G + Y R K ++LR FP D Q+ + L
Sbjct: 99 LHIINQRNLDKEL----DEIVHINSQGIVTYRQRYYGKLATSLDLRRFPFDEQTIKIELI 154
Query: 291 SYAYSNQQLVYQWQNSQSVNFVPG-MTLSQFDLISFPYRNFT--FTRREGDFSVLQVSFN 347
S++YS +++ + ++ +N + ++L + +I + + D++
Sbjct: 155 SFSYSPEEI--HFVEAEELNGISSEISLVNWSIIGLSSHSHAHYLQPEQQDYARFDYEIK 212
Query: 348 LKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
+KRH+ ++ +V P LIV +S + FW+
Sbjct: 213 VKRHSSFYAWRVLFPVALIVFMSDLVFWL 241
>UniRef50_A7UFK6 Cluster: Nicotinic acetylcholine receptor alpha
subunit; n=2; Ascaris suum|Rep: Nicotinic acetylcholine
receptor alpha subunit - Ascaris suum (Pig roundworm)
(Ascaris lumbricoides)
Length = 513
Score = 70.9 bits (166), Expect = 8e-11
Identities = 42/154 (27%), Positives = 72/154 (46%), Gaps = 5/154 (3%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL 210
++L+ NY + P P ++ + + + V E+D + + +Q W D +LS+
Sbjct: 30 DDLMVNYNKHRRPAMSPHEPVTIKLKLRLSQIIDVHEIDQIMTYSVWLKQVWIDKKLSW- 88
Query: 211 GPIRSLSLSIKML--ERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIK 268
P +S+ + E IW PD YN S + IT+ K + G++ + K
Sbjct: 89 DPKNYGGVSVLYVPYEMIWVPDIVLYNNADSN-YNITISTKAT-LHYSGEVTWEPPAIFK 146
Query: 269 AKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQ 302
+ C +++R FP D Q C L GS+ YS LV +
Sbjct: 147 SMCQIDVRWFPFDEQKCHLKFGSWTYSEDLLVLE 180
>UniRef50_UPI0000EBE733 Cluster: PREDICTED: similar to nicotinic
acetylcholine receptor alpha6 subunit; n=2; Bos
taurus|Rep: PREDICTED: similar to nicotinic
acetylcholine receptor alpha6 subunit - Bos taurus
Length = 630
Score = 70.5 bits (165), Expect = 1e-10
Identities = 53/238 (22%), Positives = 104/238 (43%), Gaps = 10/238 (4%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+ L +Y P P V + I + V E++ + + R W D +L
Sbjct: 42 LFHKLFAHYNQFIRPVENVSDPITVYFEVAITQLADVDEVNQIMETNLWLRHIWNDYKLR 101
Query: 209 FLGPIRSLSLSIKML--ERIWRPDTYFYNGKHSYVHTITVPNKLLRISQH-GDILYSMRL 265
+ P + + E IW+PD YN V V K + ++ G I ++
Sbjct: 102 W-DPTEYDGIETLRVPAEMIWKPDIVLYNNA---VGDFQVKGKTKALLKYDGMITWTPPA 157
Query: 266 TIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLI-S 324
K+ CPM++ FP D Q+C L GS+ Y ++ S+ V+ S+++++ +
Sbjct: 158 IFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSK-VDMNEFWENSEWEIVDA 216
Query: 325 FPYR-NFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y+ + + E ++ + SF ++R ++ I + +PC+ I L+ + F++ + G
Sbjct: 217 SGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCG 274
>UniRef50_A6FXF8 Cluster: Putative uncharacterized protein; n=1;
Plesiocystis pacifica SIR-1|Rep: Putative
uncharacterized protein - Plesiocystis pacifica SIR-1
Length = 394
Score = 70.5 bits (165), Expect = 1e-10
Identities = 60/225 (26%), Positives = 100/225 (44%), Gaps = 17/225 (7%)
Query: 170 PTVVQTNILIRSMGPVS---ELDMDYSMDCYFRQYWRDTRLSF----LGPIRSLSLSIKM 222
PT V+ + + S+ VS E + + + W D RL+F +G R + L +
Sbjct: 81 PTKVEVGMYLISLVEVSAPSESFPTFKAEIFLDLEWHDPRLAFSEESIGTEREVFLEHEA 140
Query: 223 ---LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFP 279
LERIW PD F N + HT ++ L I G + YS R MEL FP
Sbjct: 141 ELELERIWWPDIEFEN-EQGERHT---ESRELVIHHDGHVEYSERFQGVFTVDMELIKFP 196
Query: 280 MDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDL--ISFPYRNFTFTRREG 337
D Q+ + S+++ ++ +V++ + F ++ L + R +
Sbjct: 197 FDHQNLTIHAESFSWDDRYVVFE-PLPEKTGFNEDFKTLEWTLHDVHTEVHAKKEVRSDE 255
Query: 338 DFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGS 382
FS S N+ R GY+L ++ +P ++IV +W +FW+ E S
Sbjct: 256 AFSEYVYSVNVDRDPGYYLYKIVIPLLIIVAFNWATFWMPGEPAS 300
>UniRef50_P48182 Cluster: Acetylcholine receptor subunit beta-type
acr-2 precursor; n=3; Rhabditida|Rep: Acetylcholine
receptor subunit beta-type acr-2 precursor -
Caenorhabditis elegans
Length = 575
Score = 70.5 bits (165), Expect = 1e-10
Identities = 52/222 (23%), Positives = 102/222 (45%), Gaps = 14/222 (6%)
Query: 170 PTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKML--ERIW 227
P VV + + + V E + + + W D +L++ P ++S + +R+W
Sbjct: 85 PVVVDFGVAMILLINVDEKNQILQTNVWLTMKWNDFQLAW-NPAEYGNISNLHVPSDRVW 143
Query: 228 RPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPL 287
PD +N N + HGD+ + K+ C +++ FP D Q C L
Sbjct: 144 LPDIVLFNNADGNYEVSFKSNVF--VDHHGDVTWVPPAMFKSSCRIDVEWFPFDEQCCTL 201
Query: 288 ILGSYAYSNQQLVYQWQNS-QSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSF 346
+ GS+ Y+++++ W N+ Q+V +D+I P + + D ++ F
Sbjct: 202 VFGSWTYNSEEVRLHWYNNIQAVQLHDYSYSGIWDVIDVPGQ----LVHKPDLKENKMVF 257
Query: 347 N--LKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIV 386
N ++R T ++ + + +P +L+ LS ++F++ V SGE V
Sbjct: 258 NVVIRRKTLFYTVILIIPTVLMAFLSVMAFYL--PVDSGEKV 297
>UniRef50_Q9UGM1 Cluster: Neuronal acetylcholine receptor subunit
alpha-9 precursor; n=30; Euteleostomi|Rep: Neuronal
acetylcholine receptor subunit alpha-9 precursor - Homo
sapiens (Human)
Length = 479
Score = 70.5 bits (165), Expect = 1e-10
Identities = 60/275 (21%), Positives = 121/275 (44%), Gaps = 12/275 (4%)
Query: 117 NYANSSFEQTDVFTWKQNKRSINDAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTN 176
N+++S ++ R+ A K + +L ++Y N+ P V
Sbjct: 2 NWSHSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQ 61
Query: 177 ILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKM-LERIWRPDTYFYN 235
I + + + E + + + RQ W D L++ SI++ + +WRPD YN
Sbjct: 62 ITLSQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYN 121
Query: 236 GKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYS 295
N +LR G I + K+ C +++ FP D Q C L GS+ Y+
Sbjct: 122 KADDESSEPVNTNVVLRYD--GLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYN 179
Query: 296 NQQL-VYQWQNSQSVN-FVPGMTLSQFDLISFP-YRN-FTFTRREGDFSVLQVSFNLKRH 351
Q+ ++ +S ++ F+ + ++++ P +N ++ + + + LKR
Sbjct: 180 GNQVDIFNALDSGDLSDFIEDV---EWEVHGMPAVKNVISYGCCSEPYPDVTFTLLLKRR 236
Query: 352 TGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIV 386
+ ++++ + +PC+LI L+ +SF++ SGE V
Sbjct: 237 SSFYIVNLLIPCVLISFLAPLSFYL--PAASGEKV 269
>UniRef50_Q2XWK9 Cluster: Nicotinic acetylcholine receptor subunit
type D; n=1; Lymnaea stagnalis|Rep: Nicotinic
acetylcholine receptor subunit type D - Lymnaea
stagnalis (Great pond snail)
Length = 554
Score = 70.1 bits (164), Expect = 1e-10
Identities = 60/274 (21%), Positives = 118/274 (43%), Gaps = 12/274 (4%)
Query: 116 SNYANSSFEQTDVFTWKQNK-RSINDAVSKNITS---VLENLLKNYENSQLPTHGKGYPT 171
S+ ++ S ++ + T++ R+ N K +T + L + Y+ + P + P
Sbjct: 46 SSSSSGSVDRNNSNTFRGGPHRTTNYTGHKGLTDEQRLFYKLFEGYDPNTRPVYNASDPV 105
Query: 172 VVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKML--ERIWRP 229
V I + + + E + + + + Q W D +L + P L + +W+P
Sbjct: 106 KVLIGITLTQIFDLDEKNQVLTTNVWLDQEWTDQKLHW-NPTDYNDLKRLRIPCRHLWKP 164
Query: 230 DTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLIL 289
D YN Y T L + G + + + ++ C +++ FP D Q C + L
Sbjct: 165 DIVLYNSVEDY--TDGYMQSLAMVHHTGVVFWPPIVRFQSTCQVDITYFPFDDQVCSMKL 222
Query: 290 GSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISF-PYRNFT-FTRREGDFSVLQVSFN 347
GS+AY Q+ S V+ ++ ++ LIS RN + F + + +
Sbjct: 223 GSWAYDGFQVDVD-NRSVPVDLSNYVSNGEWHLISVTAKRNVVYYPCCTEPFHDVTFTVH 281
Query: 348 LKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
L+R T Y+ V +PC+++ L+ + FW+ + G
Sbjct: 282 LRRRTLYYTHNVIIPCVMLSSLTLLVFWMSPDSG 315
>UniRef50_P17787 Cluster: Neuronal acetylcholine receptor subunit
beta-2 precursor; n=69; Euteleostomi|Rep: Neuronal
acetylcholine receptor subunit beta-2 precursor - Homo
sapiens (Human)
Length = 502
Score = 70.1 bits (164), Expect = 1e-10
Identities = 49/221 (22%), Positives = 100/221 (45%), Gaps = 10/221 (4%)
Query: 164 THGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKML 223
T+G TV Q + + + V E + + + + Q W D RL++ +++
Sbjct: 50 TNGSELVTV-QLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLP 108
Query: 224 ER-IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDR 282
+ IW PD YN N + +S G I + K+ C +E+++FP D+
Sbjct: 109 SKHIWLPDVVLYNNADGMYEVSFYSNAV--VSYDGSIFWLPPAIYKSACKIEVKHFPFDQ 166
Query: 283 QSCPLILGSYAYSNQQ--LVYQWQNSQSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFS 340
Q+C + S+ Y + LV + + + +F P ++D+++ P R + +
Sbjct: 167 QNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPS---GEWDIVALPGRR-NENPDDSTYV 222
Query: 341 VLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ F ++R ++ I + +PC+LI L+ + F++ + G
Sbjct: 223 DITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSDCG 263
>UniRef50_UPI0000E49844 Cluster: PREDICTED: similar to nicotinic
acetylcholine receptor alpha2 subunit; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
nicotinic acetylcholine receptor alpha2 subunit -
Strongylocentrotus purpuratus
Length = 570
Score = 69.7 bits (163), Expect = 2e-10
Identities = 54/233 (23%), Positives = 98/233 (42%), Gaps = 8/233 (3%)
Query: 153 LLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGP 212
L Y P V + + + V E + + + + +Q W D +L + P
Sbjct: 86 LFYKYNRLIRPVENNSEVLDVNFRLTMSQLIDVDEKNQIMTTNVWLKQLWMDYKLQW-NP 144
Query: 213 IRSLSLSIKML--ERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAK 270
++SI + + IW PD YN + +T+ K L S G + + K+
Sbjct: 145 AEYDNISILRVPSKMIWTPDLVLYNNADGN-YEVTLMAKALVYSD-GTVYWLPPAIYKSS 202
Query: 271 CPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRNF 330
C + +R FP D Q CP+ GS+ Y L+ +S V+ ++D+I P
Sbjct: 203 CKINVRYFPFDEQFCPMKFGSWTYDG-SLIDLIPSSNDVDLEDYWQSGEWDIIGTPANKN 261
Query: 331 TFTRREGDFSVLQVSFNL--KRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
T D ++F L +R ++ + + +PC+LI L+ + F++ + G
Sbjct: 262 TLKYPCCDEIYTDITFTLHIRRKPLFYTVNLILPCVLISFLTVLVFYLPSDSG 314
>UniRef50_Q18556 Cluster: Putative uncharacterized protein acr-9;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein acr-9 - Caenorhabditis elegans
Length = 534
Score = 69.7 bits (163), Expect = 2e-10
Identities = 56/244 (22%), Positives = 106/244 (43%), Gaps = 14/244 (5%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L +L NY+ + P P VV I ++ + V E + ++ + W D +L
Sbjct: 31 LLADLRHNYDPYERPVANASEPLVVSVKIYLQQILDVDEKNQVITLVAWIEYQWTDYKLK 90
Query: 209 F----LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
+ G I+ + + IW+PD YN + T P + +S GD+L
Sbjct: 91 WDPSEYGGIKDIRIPGNA-NAIWKPDVLLYNSADENFDS-TYPVNYV-VSYTGDVLQVPP 147
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFV-PGMTL------ 317
+K C +++ FP D Q C L GS+ YS + + + N G+ +
Sbjct: 148 GILKLSCKIDITYFPFDDQICHLKFGSWTYSGNFIDLRINGPEGKNISDEGIDVQYYVQN 207
Query: 318 SQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIH 377
+++L++ P R+ T E + L ++R T Y+ + + +P LI +++ + F +
Sbjct: 208 GEWNLLAVPARHETNIFDEQPYPSLFFYLIIQRRTLYYGLNLIIPSFLISLMTVLGFTLP 267
Query: 378 REVG 381
+ G
Sbjct: 268 PDAG 271
>UniRef50_A7RLP3 Cluster: Predicted protein; n=3; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 417
Score = 69.7 bits (163), Expect = 2e-10
Identities = 63/248 (25%), Positives = 110/248 (44%), Gaps = 27/248 (10%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIR--SMGPVSELDMDYSMDCYFRQYWRDTR 206
+ ++LL Y+ LP+ P + N ++ + V + + S++C++ W ++
Sbjct: 16 IRKHLLDGYDKVVLPSE----PDRLALNFSLKFVQIMDVKDKEQLVSVECWYSMNWINSF 71
Query: 207 LSF-LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLR---ISQHGDILYS 262
L + ++ S IW PD YN V T K L + G ++S
Sbjct: 72 LKWDKKKYQNESRVFFDPSEIWVPDIALYNNGDDKVQTSGGRTKFLTNIVVEDTGKCVWS 131
Query: 263 MRLTIKAKCPMELRNFPMDRQSCPLILGSYAYS-NQQLVYQWQNSQSVNFVPGMTLSQFD 321
+T C M L +P D Q+C + GS +Y N ++ + + S+S +F+ S ++
Sbjct: 132 GPVTFTFTCSMALSRWPFDDQNCTMKFGSLSYGKNNFIISKVKVSKSDDFIEN---SNWE 188
Query: 322 LISFPYRNFTFTRREGD--------FSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVS 373
L +N T +E D FS + + N+ R Y + + PC+L+V+LS S
Sbjct: 189 L-----KNITVALQETDHGDCCLFGFSQVTYTLNMARKFKYHMFYLVAPCLLMVILSLFS 243
Query: 374 FWIHREVG 381
FWI E G
Sbjct: 244 FWIPSESG 251
>UniRef50_P54245 Cluster: Uncharacterized acetylcholine
receptor-like protein F18G5.4 precursor; n=2;
Caenorhabditis|Rep: Uncharacterized acetylcholine
receptor-like protein F18G5.4 precursor - Caenorhabditis
elegans
Length = 615
Score = 69.7 bits (163), Expect = 2e-10
Identities = 57/263 (21%), Positives = 113/263 (42%), Gaps = 8/263 (3%)
Query: 123 FEQTDVFTWKQNKRSINDAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSM 182
F+Q + + K SI+ S+L++ + YE P PT V L+ +
Sbjct: 92 FDQNRLEQALRIKGSIDGTEEALYRSLLDHTV--YEKDVRPCIHHSQPTNVTFGFLLNQI 149
Query: 183 GPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKMLE-RIWRPDTYFYNGKHSYV 241
+ E + + + W D RLS+ + S +I + RIW+PD N
Sbjct: 150 VEMDERNQALTTRSWLNINWMDPRLSWNESLWSEIKAIYIPHARIWKPDIILVNNAIREY 209
Query: 242 HTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVY 301
+ V ++ ++ G++ + ++ CP+ +R +P D Q C L S+++ + +
Sbjct: 210 YASLVSTDVM-VTSDGNVTWLFSALFRSSCPIRVRYYPFDDQQCDLKFASWSHDITE-IN 267
Query: 302 QWQNSQSVNFVPGMTLSQFDLISFP--YRNFTF-TRREGDFSVLQVSFNLKRHTGYFLIQ 358
N+ + M S+FDL+ TF + D+ ++ + ++ R +++
Sbjct: 268 LGLNTDKGDLSSYMNNSEFDLVDMTAVREVVTFPSDTNSDWPIIVIRIHMHRRPLFYVFN 327
Query: 359 VYVPCILIVVLSWVSFWIHREVG 381
VPC+LI ++ + F + E G
Sbjct: 328 HIVPCVLISSMAVLGFLMPPETG 350
>UniRef50_Q9GP98 Cluster: Acetylcholine receptor protein 22; n=3;
Caenorhabditis|Rep: Acetylcholine receptor protein 22 -
Caenorhabditis elegans
Length = 434
Score = 69.3 bits (162), Expect = 2e-10
Identities = 59/248 (23%), Positives = 111/248 (44%), Gaps = 18/248 (7%)
Query: 132 KQNKRSINDAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNIL--IRSMGPVSELD 189
K +++ +N + ++LL +Y P + Y +V+ + I ++ V+E +
Sbjct: 22 KVKNKAVEKKDDRNERELAKHLLDDYYQYTRPV--RNYSSVLNVTVQPQIYNLVEVNEQN 79
Query: 190 MDYSMDCYFRQYWRDTRLSF-LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPN 248
+ +F Q W+D L++ + I +IW PD Y +N + T + N
Sbjct: 80 EQIKILLWFPQSWKDDYLTWDPKEWNGIERIIIPKSQIWIPDGYIFN---TVEETEPLEN 136
Query: 249 KLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQS 308
R+ G + + CPM + +FP D Q C L GS++Y + + ++
Sbjct: 137 HNARVRYDGRVEVDFNKLVDLTCPMSVLSFPFDVQLCALQFGSWSYQAHAISFNVLDT-- 194
Query: 309 VNFVPGMTL-SQFDLISFPYRNFT--FTRREGDFSVLQVSF---NLKRHTGYFLIQVYVP 362
FVP + S++D++SF T + G F+V + F L+R Y+++ + +P
Sbjct: 195 --FVPKKSKNSEWDIVSFNATKMTTKYGDTLGGFNVYEEIFYYLELRRKPLYYIVVILLP 252
Query: 363 CILIVVLS 370
LIV +S
Sbjct: 253 SFLIVTVS 260
>UniRef50_Q7KT97 Cluster: CG32975-PB, isoform B; n=69;
Eumetazoa|Rep: CG32975-PB, isoform B - Drosophila
melanogaster (Fruit fly)
Length = 808
Score = 69.3 bits (162), Expect = 2e-10
Identities = 52/239 (21%), Positives = 99/239 (41%), Gaps = 11/239 (4%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRL- 207
+L +LL Y + P + P + + + + V E + + + + W D L
Sbjct: 316 LLHDLLDPYNTLERPVLNESDPLQLSFGLTLMQIIDVDEKNQLLVTNVWLKLEWNDMNLR 375
Query: 208 ---SFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
S G ++ L + RIW+PD YN N ++R +G LY
Sbjct: 376 WNTSDYGGVKDLRIPP---HRIWKPDVLMYNSADEGFDGTYQTNVVVR--NNGSCLYVPP 430
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLIS 324
K+ C +++ FP D Q C + GS+ Y QL Q Q+ + + +++L+
Sbjct: 431 GIFKSTCKIDITWFPFDDQRCEMKFGSWTYDGFQLDLQLQDETGGDISSYVLNGEWELLG 490
Query: 325 FPYRNFTFTRREGDFSVLQVSFN--LKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
P + + ++F ++R T Y+ + +PC+LI ++ + F + + G
Sbjct: 491 VPGKRNEIYYNCCPEPYIDITFAIIIRRRTLYYFFNLIIPCVLIASMALLGFTLPPDSG 549
>UniRef50_A7RFJ5 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 328
Score = 69.3 bits (162), Expect = 2e-10
Identities = 53/242 (21%), Positives = 104/242 (42%), Gaps = 16/242 (6%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L L NY+ P G P VV + + V E + Y +Q W + LS
Sbjct: 9 LLRYLFTNYDRDIHP--GGNNPVVVTFGAKLGRIAAVDEKNNVVLAHWYLKQKWVNPSLS 66
Query: 209 F----LGPIRSLSLSIKMLERIWRPDTYFYNG---KHSYVHTITVPNKLLRISQHGDILY 261
+ G + +L + +R+W PD YN K+ K+ + G +++
Sbjct: 67 WNASEFGGVNTLHVEP---DRLWVPDIVLYNNADPKNDLAGGFQYKTKI-EMQADGTMIW 122
Query: 262 SMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFD 321
+ CPM++R FP D QSC L S+ Y +L + ++ + T +++
Sbjct: 123 LAPAMFHSACPMDIRYFPFDEQSCDLQFASWMYDTSKLEMK-IDANETKVMDTFTNKEWE 181
Query: 322 L--ISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
+ ++ + +T + + ++ +L R Y+++ + PC LI +++++F + E
Sbjct: 182 IPKLTIKKKRIKYTCCPNPYEDVTITMSLVRRPYYYIMNMIFPCSLIACMTYLTFILPAE 241
Query: 380 VG 381
G
Sbjct: 242 SG 243
>UniRef50_A7RS33 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 460
Score = 68.9 bits (161), Expect = 3e-10
Identities = 54/244 (22%), Positives = 101/244 (41%), Gaps = 13/244 (5%)
Query: 145 NITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 204
++ S+ +LL NY + +P K P ++ +I + + + E + + R YW D
Sbjct: 1 HLESLKGDLLANYSRNIIPQKYKDIPIKIKFDIALNQIIDLDERLQTITTIVWVRLYWTD 60
Query: 205 TRLSF----LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDIL 260
RL + G I+S + ++W PD YN + L ++ G I
Sbjct: 61 FRLRWNHTKYGGIKSF---VTPSRQLWLPDITLYNNANDNYEKEKEEYYGLTVNSDGSIG 117
Query: 261 YSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQL-VYQWQNSQSVNFVPGMTLSQ 319
+ K+ C +++ FP D Q C L GS++Y L ++ +F +
Sbjct: 118 WYYPTIFKSSCTIDVTYFPFDDQKCILKFGSWSYHGLSLDIFHSGPGDIKSFTDN---GE 174
Query: 320 FDLISFPYRNFTFTRR--EGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIH 377
+ L+ P R + L ++R T Y+++ PC+L+ L+ + F++
Sbjct: 175 WVLVDMPATKHVTKYRCCPEPYPYLTYDIIIRRRTMYYILNFLTPCVLMSALTVLGFFLP 234
Query: 378 REVG 381
E G
Sbjct: 235 VESG 238
>UniRef50_Q4S864 Cluster: Chromosome 5 SCAF14709, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 5
SCAF14709, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 733
Score = 68.5 bits (160), Expect = 4e-10
Identities = 51/232 (21%), Positives = 99/232 (42%), Gaps = 6/232 (2%)
Query: 153 LLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGP 212
+ NY P P +VQ + + + V E++ + + R W D +L +
Sbjct: 184 IFSNYNQYIRPVENVTDPVIVQFEVSMSQLVKVDEVNQIMETNLWLRHIWNDYKLRWNPK 243
Query: 213 IRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKC 271
I++ RIW+PD YN LLR + GD+ + K+ C
Sbjct: 244 EYGGVEYIRVPSSRIWKPDIVLYNNAVGDFQVDDKTKALLRYN--GDVTWIPPAIFKSSC 301
Query: 272 PMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFP-YR-N 329
+++ FP D Q+C + GS+ Y ++ S ++N + +I P Y+ +
Sbjct: 302 KIDVTYFPFDYQNCTMKFGSWTYDKAKIDLVLIGS-TMNLKDFWETGDWLIIDAPGYKHD 360
Query: 330 FTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ E ++ + S ++R ++ I + +PC+LI L+ + F++ + G
Sbjct: 361 IKYNCCEEIYTDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCG 412
Score = 48.0 bits (109), Expect = 6e-04
Identities = 34/141 (24%), Positives = 65/141 (46%), Gaps = 6/141 (4%)
Query: 155 KNYENSQL-PTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPI 213
KN N + P + V+ + + + V+E + + + + Q+W D RLS+ P
Sbjct: 17 KNRYNPLIRPAASRSERVPVKLQVSLAQLISVNEREQIMTTNLWLMQHWVDYRLSW-DPA 75
Query: 214 RSLSLS-IKMLER-IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKC 271
+ ++ +++ R IW PD YN N ++ + G I + K+ C
Sbjct: 76 KYEGINKLRIPSRLIWLPDIVLYNNADGTYEVTVYTNAIVLFN--GSINWLPPAIYKSAC 133
Query: 272 PMELRNFPMDRQSCPLILGSY 292
+E+++FP D+Q+C L S+
Sbjct: 134 KIEVKHFPFDQQNCTLKFRSW 154
>UniRef50_Q9N5U8 Cluster: Acetylcholine receptor protein 21; n=2;
Caenorhabditis|Rep: Acetylcholine receptor protein 21 -
Caenorhabditis elegans
Length = 469
Score = 68.5 bits (160), Expect = 4e-10
Identities = 45/233 (19%), Positives = 107/233 (45%), Gaps = 5/233 (2%)
Query: 152 NLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLG 211
+LL +Y N P+ P V + + V E + + + + R +W D +L +
Sbjct: 6 DLLYDYNNEVRPSVHSKEPINVTFVFSLTQIIDVDERNQILTTNSWIRLHWVDYKLVWDP 65
Query: 212 PIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAK 270
+ I + ++IW+PD YN + + ++ + G+I + + +
Sbjct: 66 RLYQNVTRIHIPSDKIWKPDIILYNNADAQYMKSVMSTDVI-VDYLGNIHWPLSAIFTSS 124
Query: 271 CPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISF--PYR 328
CP++++++P DRQ+C L S+AY ++ ++ Q + +T +++ LI
Sbjct: 125 CPLDVKHYPFDRQTCILKYASWAYDGTKIDLLLKSEQG-DLTNYITNTEWSLIGIRAEKN 183
Query: 329 NFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
++ + + V ++R +++ + +PC+LI +++ + F++ + G
Sbjct: 184 QVIYSCCPEPYPFIDVHVTIERRAMFYVFNLILPCVLISLIALMGFYMPTDSG 236
>UniRef50_Q0GQQ7 Cluster: PH-sensitive chloride channel variant 4;
n=2; Apocrita|Rep: PH-sensitive chloride channel variant
4 - Apis mellifera (Honeybee)
Length = 489
Score = 68.5 bits (160), Expect = 4e-10
Identities = 49/168 (29%), Positives = 78/168 (46%), Gaps = 8/168 (4%)
Query: 144 KNITSVLENLLKN--YENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQY 201
K+ +L+NLL + Y+ LP +G TV ++L+ S+ E + Y ++ +Q
Sbjct: 59 KSDKEILDNLLLSTRYDKRLLPPV-QGTLTV-NVSVLLLSLASPDESSLKYEVEFLLQQQ 116
Query: 202 WRDTRLSFLGPIRSLSLS-IKMLERIWRPDTYFYNGKHSYVHTITVP-NKLLRISQHGDI 259
W D RL + + L+ I + IW PDTYF H +P + LRI ++G +
Sbjct: 117 WYDPRLRYSNRSQYEFLNAIHHYDDIWLPDTYFI--MHGDFKDPLIPVHFALRIYRNGTV 174
Query: 260 LYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQ 307
Y MR + C L FP D C + S +Y + Y W+N +
Sbjct: 175 NYLMRRHLILSCQGRLNIFPFDDPLCSFAIESISYEQTAITYVWKNDE 222
Score = 36.3 bits (80), Expect = 2.1
Identities = 13/52 (25%), Positives = 29/52 (55%)
Query: 336 EGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVI 387
+G++S L+V R ++ V++P I++V S+++FW+ ++I
Sbjct: 284 QGNYSCLKVDLIFTRDRAFYFTTVFIPGIILVTSSFITFWLEWNAVPARVMI 335
>UniRef50_P11230 Cluster: Acetylcholine receptor subunit beta
precursor; n=30; Gnathostomata|Rep: Acetylcholine
receptor subunit beta precursor - Homo sapiens (Human)
Length = 501
Score = 68.5 bits (160), Expect = 4e-10
Identities = 55/245 (22%), Positives = 105/245 (42%), Gaps = 16/245 (6%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL 210
E L Y++S P G V +++ + ++E D + S Y W D RLS+
Sbjct: 32 EKLFSGYDSSVRPAREVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLEWTDYRLSWD 91
Query: 211 GPIRSLSLSIKML-ERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKA 269
S+++ E +W PD N + + ++ +S G + + ++
Sbjct: 92 PAEHDGIDSLRITAESVWLPDVVLLNNNDGNFD-VALDISVV-VSSDGSVRWQPPGIYRS 149
Query: 270 KCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQ------WQNSQSVNFVPGMTL--SQFD 321
C +++ FP D Q+C ++ SY+Y + ++ Q Q Q ++ G + Q++
Sbjct: 150 SCSIQVTYFPFDWQNCTMVFSSYSYDSSEVSLQTGLGPDGQGHQEIHIHEGTFIENGQWE 209
Query: 322 LISFPYR-----NFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
+I P R REG + ++R ++L+ V PCILI +L+ F++
Sbjct: 210 IIHKPSRLIQPPGDPRGGREGQRQEVIFYLIIRRKPLFYLVNVIAPCILITLLAIFVFYL 269
Query: 377 HREVG 381
+ G
Sbjct: 270 PPDAG 274
>UniRef50_Q23022 Cluster: Acetylcholine receptor subunit alpha-type
unc-38 precursor; n=9; Chromadorea|Rep: Acetylcholine
receptor subunit alpha-type unc-38 precursor -
Caenorhabditis elegans
Length = 511
Score = 68.5 bits (160), Expect = 4e-10
Identities = 39/151 (25%), Positives = 72/151 (47%), Gaps = 5/151 (3%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL 210
++L+ NY + P+ P ++ + + + V E+D + + +Q W D +LS+
Sbjct: 32 DDLMVNYNRHRRPSTSPNKPLTIKLKLRLSQIIDVHEIDQIMTCSVWLKQTWIDRKLSW- 90
Query: 211 GPIRSLSLSIKML--ERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIK 268
P+ +++ + E IW PD YN S + IT+ K + G++ + K
Sbjct: 91 DPVNYGGVNVLYVPYEMIWVPDIVLYNNADSN-YNITISTKAT-LHYTGEVTWEPPAIFK 148
Query: 269 AKCPMELRNFPMDRQSCPLILGSYAYSNQQL 299
+ C +++R FP D Q C L GS+ +S L
Sbjct: 149 SMCQIDVRWFPFDEQQCHLKFGSWTFSENLL 179
>UniRef50_Q9U298 Cluster: Neuronal acetylcholine receptor subunit
eat-2 precursor; n=1; Caenorhabditis elegans|Rep:
Neuronal acetylcholine receptor subunit eat-2 precursor
- Caenorhabditis elegans
Length = 474
Score = 67.3 bits (157), Expect = 1e-09
Identities = 53/240 (22%), Positives = 113/240 (47%), Gaps = 11/240 (4%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L++L + Y+ + P P V+ ++++ + V E + ++ + + W D +L
Sbjct: 28 LLKDLREGYDPVERPVADHRKPVNVKLRLILQQLVDVDERNQVITLVVWNQYTWNDYKLR 87
Query: 209 FLGPIRSLSLSIKMLER--IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLT 266
+ P +++ + +W+PD +N + + + P ++ +S +GD+L++
Sbjct: 88 W-SPEEYGNITTLQIPHGTLWKPDILLFNSANEHFDA-SFPVHMV-VSSNGDVLFAPPGI 144
Query: 267 IKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNS-----QSVNFVPGMTLSQFD 321
+ C + + FP D+Q C L GS+ Y ++L Q +S ++ + +FD
Sbjct: 145 VSFSCSLSMTWFPYDQQVCYLKFGSWTY-GKKLDLQIDDSDLPDGHKMDLQYYIPNGEFD 203
Query: 322 LISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
L++ P + T + + L +LKR T Y+ + VP ILI + + + F + E G
Sbjct: 204 LLATPAFRKSTTFLDETYVELYFHMHLKRRTMYYGLNWIVPSILISLSNILGFTMPPECG 263
>UniRef50_UPI000041A8E7 Cluster: PREDICTED: similar to
Gamma-aminobutyric-acid receptor alpha-5 subunit
precursor (GABA(A) receptor); n=1; Homo sapiens|Rep:
PREDICTED: similar to Gamma-aminobutyric-acid receptor
alpha-5 subunit precursor (GABA(A) receptor) - Homo
sapiens
Length = 207
Score = 66.9 bits (156), Expect = 1e-09
Identities = 30/62 (48%), Positives = 41/62 (66%), Gaps = 3/62 (4%)
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFV---PGMTLSQFD 321
LTI A+CPM+L +FPMD +CPL GSYAY N ++VY W N + + V G L+Q+
Sbjct: 45 LTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYH 104
Query: 322 LI 323
L+
Sbjct: 105 LM 106
>UniRef50_A7S2N9 Cluster: Predicted protein; n=3; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 545
Score = 66.9 bits (156), Expect = 1e-09
Identities = 58/240 (24%), Positives = 105/240 (43%), Gaps = 17/240 (7%)
Query: 152 NLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRL---- 207
+L Y P K V + + + V E D + RQ W + L
Sbjct: 56 DLFAGYNPKLRPVFHKRENVTVVLGMSVHQIIDVYEKDQIIKTSFWVRQIWYNPFLRWNE 115
Query: 208 SFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRI--SQHGDILYSMRL 265
+F G I+ +++S ++W PD YN + ++ N RI S G ++ +
Sbjct: 116 TFYGGIKEINVSPL---QVWTPDLVLYNNADASTDG-SLENFKTRIIVSSDGKNMWLAPV 171
Query: 266 TIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSV--NFVPGMTLSQFDLI 323
+ C ++++ FP D Q C L GS+ + L + + Q+ F+P ++DLI
Sbjct: 172 IFSSSCTIKIKYFPFDDQYCSLKFGSWTFDGFHLDLKPEAPQASLSKFIPN---GEWDLI 228
Query: 324 SFP-YRN-FTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
P RN + + + + +L+R +FL + +PC +IVVL+ +SF++ + G
Sbjct: 229 GAPAIRNVLRYDCCPAPYPDVTFTLHLRRRVLFFLFNLIIPCFVIVVLTSLSFYLPPDSG 288
>UniRef50_A7S2J7 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 462
Score = 66.9 bits (156), Expect = 1e-09
Identities = 52/240 (21%), Positives = 106/240 (44%), Gaps = 11/240 (4%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L +L +NY++ P V+ ++ + + V+ ++ + RQ W + L+
Sbjct: 41 LLADLFRNYDSEVRPVFNDSDKVNVEFSLSLIQIIAVNSKSQLVTVSVWIRQKWTNPMLA 100
Query: 209 F----LGPIRSLSLSIKMLERIWRPDTYFYNGK-HSYVHTITVPNKLLRISQHGDILYSM 263
+ G I S++L+ ++W PD YN +Y + + S G ++
Sbjct: 101 WNTSKYGGIESVNLNPA---KVWIPDIILYNNADETYAGGLEKYKTSVIASSDGTQEWNS 157
Query: 264 RLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLI 323
+ + C + +R FP D Q+C L GS+ Y +L S S + + ++ L+
Sbjct: 158 PASFTSTCNINVRYFPFDSQNCSLKFGSWTYVGNRLT-MTSTSDSADLSKYVNNGEWHLL 216
Query: 324 SFPYR-NFTFTR-REGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ P + N F + F + + ++R Y++ + +PC LI L+ + F++ E G
Sbjct: 217 AMPAKLNRVFYNCCKYPFYDVTLYLEIQRKPLYYVFNLIIPCALIATLTLIKFFLPPESG 276
>UniRef50_Q60S81 Cluster: Neuronal acetylcholine receptor subunit
eat-2 precursor; n=1; Caenorhabditis briggsae|Rep:
Neuronal acetylcholine receptor subunit eat-2 precursor
- Caenorhabditis briggsae
Length = 477
Score = 66.5 bits (155), Expect = 2e-09
Identities = 53/241 (21%), Positives = 107/241 (44%), Gaps = 13/241 (5%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L++L + Y+ + P P V+ ++++ + V E + ++ + + W D ++
Sbjct: 26 LLKDLREGYDPMERPVSDHMKPVNVKLRLILQQLVDVDEKNQVITLVVWTQYTWNDYKMK 85
Query: 209 F----LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
+ G I SL + L W+PD +N + + + N + +S G++L++
Sbjct: 86 WSPEEYGNITSLQIPFGTL---WKPDILLFNSANEHFDSSFPVNMV--VSNDGNVLFAPP 140
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLV----YQWQNSQSVNFVPGMTLSQF 320
++ C + + FP D Q C L GS+ Y + + ++ + +F
Sbjct: 141 GIMQFSCSLSMTWFPYDEQVCYLKFGSWTYGKKLDLRIDDADLPEGHKMDLQYYVPNGEF 200
Query: 321 DLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREV 380
DLIS P + T + + L +LKR T Y+ + +P ILI + + + F + E
Sbjct: 201 DLISTPAFRKSTTFLDETYVELYFHMHLKRRTMYYGLNWIIPSILISLSNILGFTMPVEC 260
Query: 381 G 381
G
Sbjct: 261 G 261
>UniRef50_Q93329 Cluster: Putative uncharacterized protein lev-8;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein lev-8 - Caenorhabditis elegans
Length = 531
Score = 66.1 bits (154), Expect = 2e-09
Identities = 41/165 (24%), Positives = 79/165 (47%), Gaps = 10/165 (6%)
Query: 143 SKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYW 202
+K+++ +LENLL +Y + P H V+ + + V E++ + + W
Sbjct: 26 NKHVSQLLENLLTDYNKAVRPVHNASDALKVKFGANLCRLIDVDEVNQVLTTSLWLEMQW 85
Query: 203 RDTRLSF----LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGD 258
D +L++ G + + + ++IW PD YN H IT+ + L +I HG
Sbjct: 86 YDKKLTWNPTDWGGVEYIHIPS---DQIWIPDIVLYNNADGEPH-ITITS-LAKIDHHGR 140
Query: 259 ILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQL-VYQ 302
+++ K+ CP+ ++ FP D Q+C + G ++ + L +YQ
Sbjct: 141 VVWQPPSIYKSFCPINIKYFPYDWQTCEMKFGGWSNDGETLDLYQ 185
>UniRef50_Q8JFN7 Cluster: Neuronal acetylcholine receptor subunit
alpha-9-I precursor; n=8; Clupeocephala|Rep: Neuronal
acetylcholine receptor subunit alpha-9-I precursor -
Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Length = 572
Score = 65.7 bits (153), Expect = 3e-09
Identities = 54/238 (22%), Positives = 101/238 (42%), Gaps = 10/238 (4%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L +L++NY ++ P V I + + + E + + + RQ W D L
Sbjct: 28 LLNDLMENYSSALRPVEDTDKTLNVTLQITLSQIKDMDERNQVLTTYLWIRQTWFDAYLK 87
Query: 209 F-LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
+ L + +WRPD YN N +LR + G+I + M
Sbjct: 88 WDKEEYDGLEVIRIPSNLVWRPDIVLYNKADEEASGPADTNVVLRYN--GEITWDMPAIT 145
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQ--LVYQWQNSQSVNFVPGMTLSQFDLISF 325
K+ C +++ FP D Q C L GS+ Y+ Q + + +FV + +++
Sbjct: 146 KSSCVVDVSYFPFDWQWCNLTFGSWTYNGNQVDIAMGMDSGDLSDFVENV---EWECHGM 202
Query: 326 P-YRNFTFTRREGD-FSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
P RN D + + + +LKR + +++ + +PC LI L+ + F++ + G
Sbjct: 203 PAVRNVIMYGCCSDPYPDITYTLHLKRRSLFYIFNLLLPCFLISFLAPLGFYLPADSG 260
>UniRef50_P46098 Cluster: 5-hydroxytryptamine receptor 3 precursor;
n=50; Tetrapoda|Rep: 5-hydroxytryptamine receptor 3
precursor - Homo sapiens (Human)
Length = 478
Score = 65.7 bits (153), Expect = 3e-09
Identities = 53/234 (22%), Positives = 107/234 (45%), Gaps = 18/234 (7%)
Query: 153 LLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF--- 209
LL NY P PT V ++++ ++ V E + + ++RQYW D L +
Sbjct: 41 LLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPE 100
Query: 210 -LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPN-KLLRISQHGDILYSMRLTI 267
I LS+ + IW PD + +V PN + I G++ L +
Sbjct: 101 DFDNITKLSIP---TDSIWVPDILI----NEFVDVGKSPNIPYVYIRHQGEVQNYKPLQV 153
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQL-VYQWQNSQSVNFVPGMTLSQ--FDLIS 324
C +++ NFP D Q+C L S+ ++ Q + + W+ + V + ++Q ++L+
Sbjct: 154 VTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLG 213
Query: 325 -FPY-RNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
PY R F+ ++ ++ ++R ++++ + +P I ++V+ V F++
Sbjct: 214 VLPYFREFSM-ESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYL 266
>UniRef50_UPI0000E48B7E Cluster: PREDICTED: similar to neuronal
nicotinic acetylcholine receptor alpha3 subunit; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
neuronal nicotinic acetylcholine receptor alpha3 subunit
- Strongylocentrotus purpuratus
Length = 525
Score = 65.3 bits (152), Expect = 4e-09
Identities = 49/239 (20%), Positives = 104/239 (43%), Gaps = 6/239 (2%)
Query: 141 AVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQ 200
A S+ + NL ++Y P + P VV+ + I + + E + + + +
Sbjct: 28 AASRAAELLYANLTEDYNIFIRPVKNESDPVVVKFGLSISQLIAIDEKNQVMTTSVWVKH 87
Query: 201 YWRDTRLSFLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDI 259
W+D L + + + E IWRPD YN + + N +++ + G +
Sbjct: 88 EWQDHHLMWNPEDYEGITELHIPAENIWRPDILLYNNANGNFDVQFLVNAIVKYT--GTV 145
Query: 260 LYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQ 319
+ K+ C +++ FP D QSC + G + + ++ N V+ +
Sbjct: 146 TWLPPAIYKSSCTIDIEYFPFDEQSCKMKFGPWTHDTLKIDMASSN-DVVDQEDYWPNGE 204
Query: 320 FDLISFP-YRN-FTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
++++ P RN T+ + + + + F L R ++++ + VPC+LI L+ + F++
Sbjct: 205 WEIVESPATRNEITYPCCDDKYVDVTLYFKLHRKPLFYVVTLVVPCLLISFLTILVFFL 263
>UniRef50_Q6QWI5 Cluster: Acetylcholine receptor 20 (63.9 kD)
alternative variant a; n=5; Caenorhabditis|Rep:
Acetylcholine receptor 20 (63.9 kD) alternative variant
a - Caenorhabditis elegans
Length = 553
Score = 65.3 bits (152), Expect = 4e-09
Identities = 54/241 (22%), Positives = 110/241 (45%), Gaps = 10/241 (4%)
Query: 144 KNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWR 203
KN + +L Y +P+ GK P V ++ + + V+E ++ + + W
Sbjct: 22 KNQYEIANKILDKYNAGLIPSMGKKSPIEVHFSMELYQIISVNEPQQFLMLNAWVVERWT 81
Query: 204 DTRLSFLGPIRSLSLSIKMLER--IWRPDTYFYNG--KHSYVHTITVPNKLLRISQ-HGD 258
D L + P + +++ ML IW PDT YN + + K+ + + +G
Sbjct: 82 DRLLGW-DPEKFGNVTEIMLPHHFIWLPDTTLYNSLVMKDDENRRLLHAKVTTLGEGNGA 140
Query: 259 ILYSMRLTI-KAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVY-QWQNSQSVNFVPGMT 316
+ + TI K C + LR FP D QSC L+ GS+ + N ++ Y + SQ++ +
Sbjct: 141 FIELLYPTIYKLSCLLNLRFFPFDVQSCRLLFGSWTFDNTKIDYFAFNESQAIGTTNCIE 200
Query: 317 LSQFDLISFPY--RNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSF 374
++++S + ++++L+ ++R Y++I + +P +I +S + F
Sbjct: 201 NEGWNVLSTSVIRHENKYDCCPNNYTLLEFRLTIQRKPLYYIINLIIPTSIITFISIIGF 260
Query: 375 W 375
+
Sbjct: 261 F 261
>UniRef50_A7RR86 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 479
Score = 65.3 bits (152), Expect = 4e-09
Identities = 61/249 (24%), Positives = 117/249 (46%), Gaps = 23/249 (9%)
Query: 149 VLENLLKNYENSQ--LPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTR 206
++ ++ K YE ++ LP P V +I + + + + + RQ+W +TR
Sbjct: 34 LIRDITKEYELNKEILPIKNHSQPIKVIFDIAFAQLVELDSKNQIMTSYIWVRQFWSNTR 93
Query: 207 L----SFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKL-LRISQH--GDI 259
L S G S++LS + IW PD YN +S +TI K ++ H G I
Sbjct: 94 LRWDPSKYGGQTSVNLSPHL---IWLPDIVLYNNINS--NTIGEMFKFDTKVVLHNTGAI 148
Query: 260 LYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQ--QLVYQWQNSQSVNFVPGMTL 317
+ +K+ C +++ FP D+Q+C L+ GS+ Y+++ L + + + P
Sbjct: 149 EWYAPTLVKSICKIDITYFPFDKQNCSLVFGSWTYTSEFLSLDIKQKEPDLSKYTPN--- 205
Query: 318 SQFDLISFPYRNFTFTRREGDFSVLQVSF--NLKRHTGYFLIQVYVPCILIVVLSWVSFW 375
Q++++ + + + V++ +++R +F++ + +PCIL+ LS SF
Sbjct: 206 GQWEMMHAEVKRNVVKYSCCYWPYIDVTYTVHIRRRPLFFVLNLILPCILLATLSVFSFS 265
Query: 376 IHREVGSGE 384
+ GSGE
Sbjct: 266 L--PPGSGE 272
>UniRef50_UPI0000E49402 Cluster: PREDICTED: similar to alpha 10
subunit of nicotinic acetylcholine receptor; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
alpha 10 subunit of nicotinic acetylcholine receptor -
Strongylocentrotus purpuratus
Length = 473
Score = 64.9 bits (151), Expect = 5e-09
Identities = 51/242 (21%), Positives = 106/242 (43%), Gaps = 12/242 (4%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFR------QYW 202
+L ++ NY N P P V I+ + + E + +++ + R Q W
Sbjct: 21 LLNDMFANYSNIIRPVERSADPIDVLIGAAIQQIIDMDEKNQVITLNLWMRMHFLFIQQW 80
Query: 203 RDTRLSFL-GPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILY 261
D+ L + ++ I +E IWRPD + S + + + + IS G + +
Sbjct: 81 TDSNLKWNPADYGDTTVLIVPIETIWRPDIVLFTNADSSFNGMMMTSA--SISHDGIVRW 138
Query: 262 SMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFD 321
+ ++ C +++ FP D Q C L GS+AY Q+ + + S + + ++
Sbjct: 139 NAPAIYQSTCKIDITYFPFDEQHCSLKFGSWAYHGFQIDLK-NRTTSGDISAYIDNGEWT 197
Query: 322 LISFPY-RNFTFTR-REGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
L+ P RN F + ++ + ++R ++ I + PC+LI +++ + F++ +
Sbjct: 198 LVGMPVKRNLLFYNCCPEPYPDVEFTVIIRRRALFYFINLLGPCVLISLITVLDFFMPAD 257
Query: 380 VG 381
G
Sbjct: 258 AG 259
>UniRef50_A7RHV9 Cluster: Predicted protein; n=3; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 336
Score = 64.9 bits (151), Expect = 5e-09
Identities = 55/244 (22%), Positives = 109/244 (44%), Gaps = 17/244 (6%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+LE L+ + P PT V +I S+ V E S + RQ W LS
Sbjct: 15 LLERLINASGSGVRPILDLARPTNVTLDITFNSIIDVDEKHQILSSSVWIRQSWIAETLS 74
Query: 209 F----LGPIRSLSLSIKMLERIWRPDTYFYNGK-HSYVHTITVPNKLLRISQHGDILYSM 263
+ G + + +S ++L W+PDT YN + + +R+ G + ++M
Sbjct: 75 WDPAEYGGVNQIVVSSQLL---WQPDTVLYNNIFEEFDSRLDTTVTRVRVYSSGFVYWAM 131
Query: 264 RLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQ---- 319
K C +++ +FP D Q CP+ G++ Y ++ N++ + V +
Sbjct: 132 PYVFKTMCKIDVTDFPFDSQRCPITFGAWQYDQNEV--NLINNKRLATVASTRVENGEWT 189
Query: 320 FDLISFPYRNFTFTRREGDFSVLQVSF--NLKRHTGYFLIQVYVPCILIVVLSWVSFWIH 377
+ ++ R F + + ++SF +++R + ++++ + +P LI +L++ SF+I
Sbjct: 190 VEKVAIE-RRVIFYQCCPNQPYPEISFVIHMQRRSLFYVVNLVLPNFLITLLAFFSFFIP 248
Query: 378 REVG 381
E G
Sbjct: 249 VECG 252
>UniRef50_UPI0000586C99 Cluster: PREDICTED: similar to nicotinic
acetylcholine receptor subunit type A; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
nicotinic acetylcholine receptor subunit type A -
Strongylocentrotus purpuratus
Length = 357
Score = 64.5 bits (150), Expect = 7e-09
Identities = 49/204 (24%), Positives = 95/204 (46%), Gaps = 12/204 (5%)
Query: 178 LIRSMGPVSELDMDYSMDC--YFRQYWRDTRLSFLGPIRSLSLSIKML--ERIWRPDTYF 233
L + PV ++ + +S +C Y + WRD L + P +L++ + +IW PDT
Sbjct: 105 LTSEIKPVMKV-LSFSFECSSYVLKRWRDEYLMW-EPRAYNNLTVLRIPASKIWLPDTVL 162
Query: 234 YNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYA 293
YN + S + L + G + +S LT+ ++C + + +P D+Q C L +GS+
Sbjct: 163 YNTRQSNNDQLMTVETLTIVKSDGSVDWSAPLTMISECSINVYYYPFDQQECALKMGSWQ 222
Query: 294 YSNQQLVYQWQNSQSVNFVPGMTLSQFDLISF-PYRNFTFTRREGDFSVLQVSF--NLKR 350
+ + + Y + S ++D S + N D V+F N+ R
Sbjct: 223 HDRKFIDYLDGTADSAT---EQRNGEWDTTSIKAHSNIKVYSCCPDKEYPDVTFTINISR 279
Query: 351 HTGYFLIQVYVPCILIVVLSWVSF 374
++++ + VPC++I ++S + F
Sbjct: 280 KPLFYVVNLIVPCVMISMMSVLEF 303
>UniRef50_Q70GM3 Cluster: Ligand-gated chloride channel subunit
precursor; n=3; Chromadorea|Rep: Ligand-gated chloride
channel subunit precursor - Dirofilaria immitis (Canine
heartworm)
Length = 406
Score = 64.5 bits (150), Expect = 7e-09
Identities = 52/196 (26%), Positives = 90/196 (45%), Gaps = 22/196 (11%)
Query: 194 MDCYFRQYWRDTRLSFLGPIRS--LSLSIKMLERIWRPDTYFYNG---KHSYVH-TITVP 247
+D Y RQ W D RL + R + + IW PDTYF NG H +H T+ P
Sbjct: 89 VDLYLRQQWEDGRLVYELDDRDGIEEVVVPHNRHIWIPDTYFSNGHDVNHEKLHRTVVEP 148
Query: 248 NKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQ 307
+R S+ + ++ + +K P E + + L L SY Y + +VY W NS
Sbjct: 149 TGYVRSSEMRTV--TVPVEYGSKYPFE------NTRMIKLRLSSYKYPIEDIVYLWANSP 200
Query: 308 SVNFVPGMTLSQFDLISF-PYRNFTFTRREGDFSV-----LQVSFNLKRHTGYFLIQVYV 361
+P + +SQ L F ++ G++++ + V + ++++
Sbjct: 201 PT-VIP-VEVSQELLTGFYEFKEAVAEDCAGNYTIGIYSCIDVLITFTGASSEAFWRIFI 258
Query: 362 PCILIVVLSWVSFWIH 377
P IL++++SW+ FW+H
Sbjct: 259 PSILLILVSWLHFWVH 274
>UniRef50_Q2XWK7 Cluster: Nicotinic acetylcholine receptor subunit
type F; n=1; Lymnaea stagnalis|Rep: Nicotinic
acetylcholine receptor subunit type F - Lymnaea
stagnalis (Great pond snail)
Length = 488
Score = 64.5 bits (150), Expect = 7e-09
Identities = 60/262 (22%), Positives = 115/262 (43%), Gaps = 15/262 (5%)
Query: 130 TWKQNKRSINDAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIR---SMGPVS 186
T K++K + NITS + L+K + +G P VV T+ +R + +
Sbjct: 21 TKKESKEDKDFDDELNITSKEKILVKRLIDRYARMGKEGRP-VVNTSDAVRVEFGLSLIQ 79
Query: 187 ELDMDYS-----MDCYFRQYWRDTRLSFLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSY 240
LD+D + ++ W D L + +++ E IW PD YN
Sbjct: 80 ILDVDVKDQVLKTNVWYEYTWSDVLLKWDIEQYDNITDVRIPSEHIWLPDILLYNFADDR 139
Query: 241 VHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQL- 299
+ N L+ +S G +L+ + +++ C FP D Q+C L GS++Y+ +L
Sbjct: 140 LKEQR--NALVVVSHDGSLLWMPQAILRSSCAFNTLYFPFDEQTCVLKFGSWSYNGFKLD 197
Query: 300 VYQWQNSQSVNFVPGMTLSQFDLI-SFPYRNF-TFTRREGDFSVLQVSFNLKRHTGYFLI 357
++ Q + + + +++ +I + YRN +T + L+ +R ++
Sbjct: 198 IHFKQGRDKFDLMDYIENNEWTIIENEGYRNIKMYTCCPEPYPDLKFKLVFRRRVAFYTF 257
Query: 358 QVYVPCILIVVLSWVSFWIHRE 379
+ +PC L+ +L+ V FW+ E
Sbjct: 258 ILIMPCALLSLLTMVIFWVPPE 279
>UniRef50_UPI0000E49401 Cluster: PREDICTED: similar to alpha 10
subunit of nicotinic acetylcholine receptor; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
alpha 10 subunit of nicotinic acetylcholine receptor -
Strongylocentrotus purpuratus
Length = 347
Score = 64.1 bits (149), Expect = 9e-09
Identities = 41/160 (25%), Positives = 75/160 (46%), Gaps = 9/160 (5%)
Query: 226 IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSC 285
IW+PD YN S N +S G + + ++ C + + FP D+Q C
Sbjct: 117 IWKPDILLYNNADSSFKGAMKTNAA--VSNDGIVTWFAPAIFRSSCKININYFPFDKQEC 174
Query: 286 PLILGSYAYSNQ--QLVYQWQNSQSVNFVPGMTLSQFDLISFPYRN--FTFTRREGDFSV 341
L GS+AY+ + L+ + + + NF + ++ L FP + + FSV
Sbjct: 175 TLQFGSWAYTTEHLNLLNRSASGDTGNF---LVNGEWKLEDFPVIRTLHQYGCCKYPFSV 231
Query: 342 LQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
L ++R +++I + VPCIL+ L+ ++F++ + G
Sbjct: 232 LDFVLIIRRRPLFYVINMLVPCILVSALTLLTFYLPADTG 271
>UniRef50_Q7ZTN5 Cluster: MGC52789 protein; n=1; Xenopus laevis|Rep:
MGC52789 protein - Xenopus laevis (African clawed frog)
Length = 459
Score = 64.1 bits (149), Expect = 9e-09
Identities = 46/166 (27%), Positives = 76/166 (45%), Gaps = 11/166 (6%)
Query: 224 ERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQ 283
E +W+PD Y Y + +P + G + L I + C + + FP D Q
Sbjct: 107 ESLWKPDLYIYQITEVDDKSPVIP--YFTVHYDGKVTLDKPLRILSSCDVNIYKFPFDTQ 164
Query: 284 SCPLILGSYAYSNQQ-LVYQWQNSQSV---NFVPGMTLSQFDLISFPYRNFTFTRREGD- 338
+C L GSY Y+ + L++ NS V +F + ++LI+ F T +GD
Sbjct: 165 TCSLTFGSYIYTVKDILMHPKLNSSEVDDKSFAAFVGKGDWNLINVDVSEFELT--DGDV 222
Query: 339 FSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGE 384
+S + +KR ++I + +P +V+L S +I VGSGE
Sbjct: 223 YSKVAYMITIKRAPVVYVINIIIPACFMVLLDIASMFI--PVGSGE 266
>UniRef50_Q9NA46 Cluster: Putative uncharacterized protein acr-24;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein acr-24 - Caenorhabditis elegans
Length = 540
Score = 64.1 bits (149), Expect = 9e-09
Identities = 44/229 (19%), Positives = 103/229 (44%), Gaps = 12/229 (5%)
Query: 157 YENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSL 216
Y++ P PT V ++ + + ++E + ++ + Q W D L + + +
Sbjct: 11 YDSRVRPVMNHSKPTTVSFSMSLYQILSINEKQQNVDLNVWAIQKWNDDFLGWNPYLYGM 70
Query: 217 -SLSIKMLERIWRPDTYFYNG-------KHSYVHTITVPNKLLRISQHGDILYSMRLTIK 268
+ +I + IW PDTY YN Y++ + N + ++ + +
Sbjct: 71 INTTILPFDAIWLPDTYLYNSVVMNREETERYINVVVTTN-YWKGETGAEVKFMYPALYR 129
Query: 269 AKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYR 328
C +++R FP D+Q+C L + S+ S + Y+ ++ +SVN + ++ ++SF +
Sbjct: 130 TSCLLDIRFFPYDQQACKLTISSWTSSKSDINYEPEH-ESVNMDNFLPNEEWVVVSFNIK 188
Query: 329 NF--TFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFW 375
F + +L+ ++R Y+++ + +P +I +++ F+
Sbjct: 189 RVEEKFVCCPEPWVLLEAVLVVRRKPLYYIVNLVIPTSVITLVAVTGFF 237
>UniRef50_Q22224 Cluster: Putative uncharacterized protein acr-14;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein acr-14 - Caenorhabditis elegans
Length = 500
Score = 64.1 bits (149), Expect = 9e-09
Identities = 39/157 (24%), Positives = 76/157 (48%), Gaps = 8/157 (5%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L+ L +NY++ + P P V+ L+ + V E + S+ Y +W D +L+
Sbjct: 24 LLQYLKENYDSFERPVENSSAPLDVKVRFLLNQIMDVDEKNQVMSILAYMDYHWNDYKLT 83
Query: 209 F----LGPIRSLSLS--IKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYS 262
+ G IR + S ++WRPD +N + T ++ + +S +GD+ +
Sbjct: 84 WDPKLFGGIRDVRFSGDDDASFKLWRPDVLLFNSVSESFDS-TYSSRFI-VSSNGDVQQN 141
Query: 263 MRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQL 299
+ C +++ +P D+Q+C L LGS+ Y+ Q +
Sbjct: 142 PPGIFRFVCQIDVTYYPFDKQTCFLKLGSWTYNGQYI 178
>UniRef50_O16926 Cluster: Acetylcholine receptor protein 15; n=2;
Caenorhabditis|Rep: Acetylcholine receptor protein 15 -
Caenorhabditis elegans
Length = 479
Score = 64.1 bits (149), Expect = 9e-09
Identities = 48/236 (20%), Positives = 101/236 (42%), Gaps = 12/236 (5%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
++ +L+ Y + PT P VV + ++ + +SE + ++ + + WRD L
Sbjct: 25 LINDLMSGYVREERPTLDSSKPVVVSLGVFLQQIINLSEKEEQLEVNAWLKFQWRDENLR 84
Query: 209 FLGPIRSLSLSIK-MLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQH-GDILYSMRLT 266
+ ++ + +W PD YN S + K+ ++ H G+I +
Sbjct: 85 WEPTAYENVTDLRHPPDALWTPDILLYNSVDSEFDS---SYKVNLVNYHTGNINWMPPGI 141
Query: 267 IKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFP 326
K C +++ FP D Q C GS+ Y+ ++ + + F+P ++ +I +
Sbjct: 142 FKVSCKLDIYWFPFDEQVCYFKFGSWTYTRDKIQLEKGDFDFSEFIPN---GEWIIIDY- 197
Query: 327 YRNFTFTRRE---GDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
N T + E + + + +L+R T Y+ + P +L ++L + F + E
Sbjct: 198 RTNITVKQYECCPEQYEDITFTLHLRRRTLYYSFNLIAPVLLTMILVILGFTVSPE 253
>UniRef50_P91766 Cluster: Acetylcholine receptor subunit alpha-like
precursor; n=31; Coelomata|Rep: Acetylcholine receptor
subunit alpha-like precursor - Manduca sexta (Tobacco
hawkmoth) (Tobacco hornworm)
Length = 516
Score = 64.1 bits (149), Expect = 9e-09
Identities = 58/246 (23%), Positives = 110/246 (44%), Gaps = 21/246 (8%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF- 209
++LL NY P V+ + + + V+ + + + + Q W D +LS+
Sbjct: 30 DDLLSNYNKLVRPVLNVSDALTVRIKLKLSQLIDVNLKNQIMTTNLWVEQSWYDYKLSWE 89
Query: 210 ---LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLT 266
G + L + + IWRPD YN +T+ K ++ G + +
Sbjct: 90 PREYGGVEMLHVPS---DHIWRPDIVLYNNADGNFE-VTLATKAT-LNYTGRVEWRPPAI 144
Query: 267 IKAKCPMELRNFPMDRQSCPLILGSYAYSNQQL-VYQWQNSQSVNFVP-GMTLSQF---- 320
K+ C +++ FP D+Q+C + GS+ Y Q+ + + N V G+ LS+F
Sbjct: 145 YKSSCEIDVEYFPFDQQTCVMKFGSWTYDGFQVDLRHIDEVRGTNVVELGVDLSEFYTSV 204
Query: 321 --DLISFP-YRNFTFTRREGDFSVLQVSFN--LKRHTGYFLIQVYVPCILIVVLSWVSFW 375
D++ P RN F D L ++FN ++R T ++ + + +PC+ I L+ + F+
Sbjct: 205 EWDILEVPAVRNEKFYTC-CDEPYLDITFNITMRRKTLFYTVNLIIPCMGISFLTVLVFY 263
Query: 376 IHREVG 381
+ + G
Sbjct: 264 LPSDSG 269
>UniRef50_UPI00015A3E3C Cluster: Neuronal acetylcholine receptor
subunit alpha-4 precursor.; n=1; Danio rerio|Rep:
Neuronal acetylcholine receptor subunit alpha-4
precursor. - Danio rerio
Length = 556
Score = 63.7 bits (148), Expect = 1e-08
Identities = 51/237 (21%), Positives = 106/237 (44%), Gaps = 8/237 (3%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L +LL Y P H V + I + V E + + + + +Q W D RL
Sbjct: 33 LLNSLLSAYSKLTRPVHSVSDVVHVHFGLSIAQLIDVDEKNQMMTTNVWVKQEWLDYRLR 92
Query: 209 FLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
+ S+++ + IW+PD YN T+T K + G + +
Sbjct: 93 WTPEDNGNVSSMRIPAQFIWKPDIVLYNNADGDF-TVTHLTKA-HLLHDGRVTWIPPAIY 150
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPY 327
K+ C +++ P D+Q+C + GS+ Y + + + + SV+ + ++ LI+
Sbjct: 151 KSSCSIDVTFLPFDQQNCTIKFGSWTYDRSK-IDLIRIADSVDQLDYWESGEW-LITSAV 208
Query: 328 RNFTFTRRE---GDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ + E +++ + SF ++R ++ I + +PC+LI+ L+ + F++ + G
Sbjct: 209 ATYNVKKYECCSEEYADITYSFIIRRLPLFYTINLIIPCLLILCLTVLVFYLPSDCG 265
>UniRef50_A7SNK1 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 526
Score = 63.7 bits (148), Expect = 1e-08
Identities = 55/217 (25%), Positives = 99/217 (45%), Gaps = 14/217 (6%)
Query: 183 GPVSELDMDYSMDCYFRQYWRDTRL----SFLGPIRSLSLSIKMLERIWRPDTYFYNGKH 238
G + E D + + R W + L S G I L++S ++ W PD +N
Sbjct: 121 GELIEKDQVLISNIWVRMNWNNHLLRWNASEYGGIDKLNISPTLM---WLPDIVLHNNAE 177
Query: 239 SYVHTITVPNKLLRISQHGDIL--YSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSN 296
V T+ ++ D L + I++ C +++ FP D Q C L GS+ Y+
Sbjct: 178 ENVPAGTLYQFKTKVQLFNDGLCVWYAPTIIQSGCNIDITYFPFDDQLCELKFGSWTYNG 237
Query: 297 QQL-VYQWQNSQSVNFVPGMTLSQFDLISFPY-RNF-TFTRREGDFSVLQVSFNLKRHTG 353
++ + Q + + F M S+F LIS RN TF+ + + +L+R G
Sbjct: 238 LEVNIVQMLDQADLKFY--MKSSEFQLISAKAKRNVNTFSCCPEPYPDVTFYLHLRRKPG 295
Query: 354 YFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVIDDS 390
+FL + +PC++I L+ ++F + E+G ++ +S
Sbjct: 296 FFLYNIIIPCLVITSLAVLTFVLPPEIGERVTLVIES 332
>UniRef50_A4TVG5 Cluster: Glycine receptor, alpha 4 subunit; n=1;
Magnetospirillum gryphiswaldense|Rep: Glycine receptor,
alpha 4 subunit - Magnetospirillum gryphiswaldense
Length = 356
Score = 63.3 bits (147), Expect = 2e-08
Identities = 60/254 (23%), Positives = 109/254 (42%), Gaps = 22/254 (8%)
Query: 160 SQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSL--- 216
++LP G+G+P +++ + + ++E + ++ R WRD RL++ ++
Sbjct: 24 TELPW-GQGFPVLIRAGLSFVEVQAITENEGTFTATVDMRLRWRDLRLAYPAEAKAAGYQ 82
Query: 217 ----SLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCP 272
+ K L IW P F N V T + LRIS +G + R T
Sbjct: 83 EYRNDAAEKRLAEIWNPGVVFSN----MVGEPTYQKRGLRISPNGQVELMQRTTATFTAS 138
Query: 273 MELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFD-----LISFPY 327
L FP DRQ + L S Q++ ++ + + F +S+ D L+
Sbjct: 139 FPLDKFPFDRQKLNVDLVSRLEPIQRVQLDFRQDE-LEFSNTRYISEIDGWIPGLVELAQ 197
Query: 328 RNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVI 387
R E + + +QV+ +KR G L ++VP +++ + W++R + GE V+
Sbjct: 198 APVAAWRGEIN-TGMQVALVVKRDQGSLLATIFVPLFASLLIPLLVVWLNR-IEDGEFVV 255
Query: 388 DDSEWEELIEEVGG 401
D E + +GG
Sbjct: 256 DSFELTNI--SIGG 267
>UniRef50_A7RNI2 Cluster: Predicted protein; n=3; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 485
Score = 63.3 bits (147), Expect = 2e-08
Identities = 55/240 (22%), Positives = 102/240 (42%), Gaps = 11/240 (4%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L +L K+Y P K VQ ++ + ++ D +FRQ W + L+
Sbjct: 30 LLNDLFKDYNKEARPVLNKSEAIEVQFDMAYAQLINLNSKDQILQSKVWFRQRWVNPFLT 89
Query: 209 F----LGPIRSLSLSIKMLERIWRPDTYFY-NGKHSYVHTITVPNKLLRISQHGDILYSM 263
+ G + S++++ M IW+PD Y N I + I +G +
Sbjct: 90 WDPKMYGGLTSINVNPNM---IWKPDIVLYHNIGFGETGAIYKFDTRATIMHNGYTEWFA 146
Query: 264 RLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLI 323
I + C +++ FP D Q C + GS++YS +QL S + ++DL+
Sbjct: 147 PTEIHSICAIDITYFPFDEQFCKMKFGSWSYSGRQLNLT-SKGDSADLSKYTKSGEWDLL 205
Query: 324 SF-PYRNFT-FTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
RN ++ F + + +++R ++L + PCI++ L+ SF + E G
Sbjct: 206 GMRAVRNVVKYSCCPDPFIDITFTMHIRRKVLFYLTNLIAPCIVLATLTVFSFQLPLESG 265
>UniRef50_Q27218 Cluster: Acetylcholine receptor subunit beta-type
lev-1 precursor; n=6; Caenorhabditis|Rep: Acetylcholine
receptor subunit beta-type lev-1 precursor -
Caenorhabditis elegans
Length = 507
Score = 63.3 bits (147), Expect = 2e-08
Identities = 50/238 (21%), Positives = 102/238 (42%), Gaps = 12/238 (5%)
Query: 149 VLENLLKNYENSQLPTHGKG-YPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRL 207
++ +L + Y + P + P +V+ + + + V E + + + W D +L
Sbjct: 41 LMVDLFRGYNSLVQPVRNRSELPMIVKIGMQLVLLINVDEKEQVMHTNVWLTMKWDDFQL 100
Query: 208 SFLGPIRSLSLSIKML-ERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLT 266
+ + I++ E++W PD +N + N L I G +L+
Sbjct: 101 KWDPRDYANITQIRVAPEKVWLPDIVLFNNADGNYEVSFMCNVL--ILSTGTVLWVPPAI 158
Query: 267 IKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFP 326
K+ C +++ FP D Q C L GS+ Y+ ++ + S V+F T S +D++ P
Sbjct: 159 YKSSCIIDVEFFPFDDQLCSLTFGSWTYNRDEIKLDFLTSDRVDFSEYSTSSIWDMMDGP 218
Query: 327 YRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGE 384
D S ++ ++R T ++ + + +P +L+ L+ F++ SGE
Sbjct: 219 ------AVLTSDRSRIEFQIRIRRKTLFYTVVLILPTVLMAFLNVTVFYL--PTASGE 268
>UniRef50_UPI0000E473D1 Cluster: PREDICTED: similar to neuronal
acetylcholine receptor subunit alpha-9 precursor; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
neuronal acetylcholine receptor subunit alpha-9
precursor - Strongylocentrotus purpuratus
Length = 510
Score = 62.9 bits (146), Expect = 2e-08
Identities = 52/240 (21%), Positives = 107/240 (44%), Gaps = 16/240 (6%)
Query: 151 ENLLKNYENSQL-PTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF 209
E L KNY + + P + VV +LI + E + + RQ WRD L +
Sbjct: 103 ETLAKNYGSPSIRPVNNASKTVVVSFRVLISQVILFDERKQHVQLSGWRRQDWRDEFLQW 162
Query: 210 ----LGPIRSLSLSIKMLERIWRPD-TYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
G + +++ S + IW+PD T N +++ + + ++ G + +
Sbjct: 163 DPDDYGGLETITFS---KDGIWKPDITLIENVNQDFINEFSAD---VIVTYDGSVTWFTP 216
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVN---FVPGMTLSQFD 321
+ + + C + +R FP D Q+C + S+AY + + Q ++ N F+ S +
Sbjct: 217 IILTSACMVGVRYFPFDFQTCQMTYMSWAYDSNGIYLQLPTNEDPNQSVFLQNGVWSLQN 276
Query: 322 LISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
++ +N T+ E +S + L+R G++++ + +P L+ ++ + F + E G
Sbjct: 277 SVAH-QKNETYACCETPYSQIVYELILERSYGFYVLNIVLPSGLLAFVNCLVFLLPPESG 335
>UniRef50_Q4T6F3 Cluster: Chromosome 7 SCAF8790, whole genome
shotgun sequence; n=2; Clupeocephala|Rep: Chromosome 7
SCAF8790, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 66
Score = 62.9 bits (146), Expect = 2e-08
Identities = 24/51 (47%), Positives = 36/51 (70%)
Query: 337 GDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVI 387
G + L +SF LKR+ GYF++Q Y+P ILI +LSWVSFWI+ + + + +
Sbjct: 3 GSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVAL 53
>UniRef50_O61519 Cluster: Ligand-gated ion channel protein 6; n=4;
Caenorhabditis elegans|Rep: Ligand-gated ion channel
protein 6 - Caenorhabditis elegans
Length = 462
Score = 62.9 bits (146), Expect = 2e-08
Identities = 57/240 (23%), Positives = 106/240 (44%), Gaps = 22/240 (9%)
Query: 143 SKNITSVLENLL-KNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQY 201
+ N ++L+ L + Y+ P+ T+ ++ SM E + YS + R Y
Sbjct: 25 TSNTETLLQQLFNQTYDVDMKPSDDLTMVTITPNTFILLSMDQTQET-IQYSEEFLLRWY 83
Query: 202 -----WRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQH 256
W + +S+ +S S R W PD F NG + ++ + +
Sbjct: 84 DPILHWNQSAVSYENDWIKISAS-----RAWIPDVIFTNGI-DMDPLLDKDMQMADLRYN 137
Query: 257 GDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMT 316
G+I S + + CP+E+ NFP D Q C + +GS+A+ + L Q S ++ +P
Sbjct: 138 GEIRTSRPAVVSSPCPLEIDNFPYDVQKCNISMGSWAFDRRFLSVQ---SSTIEILPQKG 194
Query: 317 L----SQFDLIS-FPYRNFTF-TRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLS 370
S+++LIS R+ ++ T E FS + LKR Y+++ + P ++ ++
Sbjct: 195 RFEGNSEWELISILTVRSDSYDTLLEEWFSEITYVVTLKRKPVYYVLVIQAPTFILCTIT 254
>UniRef50_UPI0000D55EDD Cluster: PREDICTED: similar to CG11822-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG11822-PA, isoform A - Tribolium castaneum
Length = 438
Score = 62.5 bits (145), Expect = 3e-08
Identities = 52/237 (21%), Positives = 101/237 (42%), Gaps = 13/237 (5%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF- 209
++LL NY+ P VV + IR + ++E + + R W+D +L +
Sbjct: 45 QDLLLNYDKFARPAQHYNTTKVV-FGLTIRHI-ELNEFKSTLVVHSWIRLSWKDEKLQWN 102
Query: 210 ---LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLT 266
G + +L+L+ IW+PD + YN S T N + + GD+L+
Sbjct: 103 STNYGGLETLNLAD---HEIWQPDIFLYNSATSSGIT-HYGNVNCIVYEGGDVLWVPPAQ 158
Query: 267 IKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLI--S 324
C + L+ +P D Q C +I GS+ Y+ Q+ N V + S+++++ S
Sbjct: 159 FSVLCNLNLKYWPFDTQRCEMIFGSWTYNGDQIDIDPDN-DGVKMELLIENSEWNIVDKS 217
Query: 325 FPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ + + + L R + + + P ++++L V+FW+ + G
Sbjct: 218 LKKNMKYYACCPSPYPDITIDLTLSRISPSYKALIVTPAFVVIILVLVNFWLPPQAG 274
>UniRef50_A7RK99 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 446
Score = 62.5 bits (145), Expect = 3e-08
Identities = 50/237 (21%), Positives = 101/237 (42%), Gaps = 9/237 (3%)
Query: 152 NLLKNYENSQLPTHGKGYPTVVQTNIL-IRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL 210
+LLK+Y+ P + T +L I + V + S++ + Q W+D L +
Sbjct: 34 DLLKDYDRIVGPVSHSPRSLLELTFVLKITKLNKVDTKNQVISVNAWVFQQWKDPSLQWD 93
Query: 211 GPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTI---TVPNKLLRISQHGDILYSMRLTI 267
+L + + IW PD N VH + N + Q G + + + +
Sbjct: 94 KAKYNLHKTRFSPKEIWVPDVSLINNGDKLVHVAGGAELFNADTVVRQSGKVDWIAQASF 153
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPY 327
+ C + +R +PMD Q C L S+ Y+ ++ + NS ++ +++D+++
Sbjct: 154 TSTCNLRVRFWPMDDQFCTLTFSSWTYTESEIALKMDNSGLT--TGHLSNNEWDILNITV 211
Query: 328 RNFTFTRR---EGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ + +FS + + +++R + L + P +++ LS SF I E G
Sbjct: 212 KRGLLDHNNCCDANFSSVSYTIHMRRKPLFLLFYLASPAVILAALSLASFAIPAESG 268
>UniRef50_A0YQU9 Cluster: Putative uncharacterized protein; n=1;
Lyngbya sp. PCC 8106|Rep: Putative uncharacterized
protein - Lyngbya sp. PCC 8106
Length = 343
Score = 62.1 bits (144), Expect = 4e-08
Identities = 42/207 (20%), Positives = 86/207 (41%), Gaps = 8/207 (3%)
Query: 171 TVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPD 230
T V + + + + E + +D + W+D L S++ K L+ IW P
Sbjct: 45 TEVSVGLYVIDLFKIDEARQSFEVDFFIEFRWKDPHLVMSQSHCSIASCRKNLDEIWHPA 104
Query: 231 TYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILG 290
+N ++ +T + ++ G ++ R P+ L+ FP D Q+ + +
Sbjct: 105 ARIFNQRN-----LTKNFETTVVAPDGTVVCGQRFHGLVSSPLNLKRFPFDEQTLRIQIM 159
Query: 291 SYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRNFT--FTRREGDFSVLQVSFNL 348
S+ +S ++ + N ++L + N + + F +
Sbjct: 160 SFVFSPDEVQFV-VNHHLTGLAEEISLPNWSTNIPVAHNGSRHIAQLNQSFVCFDYELKV 218
Query: 349 KRHTGYFLIQVYVPCILIVVLSWVSFW 375
KR+T Y++ +V +P ILIV++S+ FW
Sbjct: 219 KRYTAYYITRVILPLILIVLMSYAVFW 245
>UniRef50_Q9VPQ8 Cluster: CG11822-PA, isoform A (Nicotinic
acetylcholine receptor beta subunit) (Nicotinic
acetylcholine receptor beta 3 (Dbeta3) subunit); n=4;
Sophophora|Rep: CG11822-PA, isoform A (Nicotinic
acetylcholine receptor beta subunit) (Nicotinic
acetylcholine receptor beta 3 (Dbeta3) subunit) -
Drosophila melanogaster (Fruit fly)
Length = 441
Score = 61.7 bits (143), Expect = 5e-08
Identities = 52/241 (21%), Positives = 101/241 (41%), Gaps = 19/241 (7%)
Query: 153 LLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDT-RLSFLG 211
L NY++ P +G PT V +++ + + EL+ + C+ WRD R+
Sbjct: 58 LFTNYDSDVQPVF-QGTPTNVSLEMVVTYID-IDELNGKLTTHCWLNLRWRDEERVWQPS 115
Query: 212 PIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKC 271
+++ +W P +NG + T + +S G + A C
Sbjct: 116 QYDNITQITLKSSEVWTPQITLFNGDEGGLMAETQ----VTLSHDGHFRWMPPAVYTAYC 171
Query: 272 PMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRNFT 331
+ + N+P D+QSC L +GS+ V +N + G +L DL+ P
Sbjct: 172 ELNMLNWPHDKQSCKLKIGSWGLK----VVLPENGTA----RGESLDHDDLVQSPEWEIV 223
Query: 332 FTRR----EGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVI 387
+R + + ++ + +R + + +Y P IV+L+ +FW+ +G +I+I
Sbjct: 224 DSRAHFVSQDYYGYMEYTLTAQRRSSMYTAVIYTPASCIVILALSAFWLPPHMGGEKIMI 283
Query: 388 D 388
+
Sbjct: 284 N 284
>UniRef50_Q2XWL1 Cluster: Nicotinic acetylcholine receptor subunit
type B; n=1; Lymnaea stagnalis|Rep: Nicotinic
acetylcholine receptor subunit type B - Lymnaea
stagnalis (Great pond snail)
Length = 527
Score = 61.7 bits (143), Expect = 5e-08
Identities = 38/158 (24%), Positives = 76/158 (48%), Gaps = 6/158 (3%)
Query: 226 IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSC 285
IW+PD YN ++ L +S +G++++ + K+ C +++R+FP D Q C
Sbjct: 114 IWKPDIKLYN--YADTRLEEKREALCVLSSNGEVVWIPQAVFKSSCSIDIRHFPFDVQRC 171
Query: 286 PLILGSYAYSNQQLVYQWQNSQSVNFVPG--MTLSQFDLI-SFPYRNFT-FTRREGDFSV 341
+ GS+ Y +L Q++ F + +++D++ S RN + +
Sbjct: 172 DMKFGSWTYDGSKLDIQFRYPDVKGFEMDDYIVSNEWDIVESNAKRNVKYYLCCPEPYVD 231
Query: 342 LQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
L S ++R ++ + +PC+L+ L+ V FW+ E
Sbjct: 232 LVFSLTIRRKVAFYSYILILPCVLLSSLTLVLFWLPPE 269
>UniRef50_O61216 Cluster: Ligand-gated ion channel protein 30; n=3;
Caenorhabditis|Rep: Ligand-gated ion channel protein 30
- Caenorhabditis elegans
Length = 529
Score = 61.7 bits (143), Expect = 5e-08
Identities = 42/188 (22%), Positives = 81/188 (43%), Gaps = 10/188 (5%)
Query: 193 SMDCYFRQYWRDTRLSF----LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPN 248
++ Y +W D + + G I + + IK IW+P+ Y Y+ + V P+
Sbjct: 112 TVSAYLDVHWNDDFIKWKPEIFGGIERIFVPIKW---IWKPEFYMYHSVYGRVPDYA-PD 167
Query: 249 KLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQ--QLVYQWQNS 306
+ +G + + ++ K+ CP+ + FP D Q+C GS+AY + LV Q
Sbjct: 168 ASAELHYNGLVRMFVSISSKSFCPINFKRFPFDSQTCSFSCGSWAYQSNIVNLVAAKQEI 227
Query: 307 QSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILI 366
+F D F + FS++ + +LKR + Y++ + P L+
Sbjct: 228 ALEDFYDNQEWLLTDARLFNGTTRNVSAANESFSMVYMQLDLKRQSFYYVFNLVFPTTLV 287
Query: 367 VVLSWVSF 374
+++ + F
Sbjct: 288 SLVAVIGF 295
>UniRef50_A7T134 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 301
Score = 61.7 bits (143), Expect = 5e-08
Identities = 46/237 (19%), Positives = 93/237 (39%), Gaps = 4/237 (1%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L+ L + Y+ P ++ + I+ + + + + + Q WRD +L
Sbjct: 4 LLDQLFQGYDKRVRPVTDPSDVVELKLGLKIQKIVKIDSKEQEMITRVWVTQVWRDPKLR 63
Query: 209 F-LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKL---LRISQHGDILYSMR 264
+ + + IW PD YN V K + ++ G +++
Sbjct: 64 WDVEKGGGIETIFVDPSEIWTPDISLYNNADDSVSVAGSEKKFQTKIVVANTGKVVWQSP 123
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLIS 324
T +++C +++R +P D Q C + GS+ + L S M +D+
Sbjct: 124 ATFRSECSIKIRYWPFDVQKCSMTFGSFIFPASALNVTSLYDSSFYTDRFMQSGDWDIKE 183
Query: 325 FPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ S L++ ++R Y++I + PC L++ L+ +SF I E G
Sbjct: 184 VSLGRADTRPGKTTVSTLRLQITVERKPIYYIIYLISPCSLLLFLALMSFTIPSESG 240
>UniRef50_UPI00015B4A35 Cluster: PREDICTED: similar to nicotinic
acetylcholine receptor alpha9 subunit; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to nicotinic
acetylcholine receptor alpha9 subunit - Nasonia
vitripennis
Length = 431
Score = 61.3 bits (142), Expect = 6e-08
Identities = 46/231 (19%), Positives = 103/231 (44%), Gaps = 10/231 (4%)
Query: 152 NLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELD--MDYSMDCYFRQYWRDTRLSF 209
+L Y+ S P K T V +++IR M ++ +D + + + W D L++
Sbjct: 38 HLFCEYDTSIRPVLSKN--TAVNVSVVIRPM-LMNFIDDKSTFILHAWISFEWTDQHLTW 94
Query: 210 LGP-IRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIK 268
+ + + IW PD YN +P L ++S G ++ + K
Sbjct: 95 KPEDFDGVQETRVKSDEIWVPDFALYNSGDMETSQTGIPETLCQLSHTGSVICLPSIKYK 154
Query: 269 AKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISF--P 326
C + +P D+Q+C L +GS+ ++ +++ + ++NS S++ +++ ++++
Sbjct: 155 TLCESDFTYWPYDKQTCTLRMGSWTHTGEEISFDFKNS-SIDMSNYRENNEWKILNYTAS 213
Query: 327 YRNFTFTRREGD-FSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
+N ++ + F L + F L RH P ++++V++ W+
Sbjct: 214 KKNPKYSCCPNETFPSLLLDFELARHPTMLHAAYITPAVVLMVITLTVLWL 264
>UniRef50_Q4RRI3 Cluster: Chromosome 16 SCAF15002, whole genome
shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 16
SCAF15002, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 636
Score = 61.3 bits (142), Expect = 6e-08
Identities = 47/244 (19%), Positives = 98/244 (40%), Gaps = 6/244 (2%)
Query: 141 AVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQ 200
A K +L +L NY ++ P V + + + + E + + + R+
Sbjct: 5 AHGKYAQKLLTDLFSNYTSALRPVEDTHNILNVTLQVTLSQIIDMDERNQILTAYLWIRR 64
Query: 201 YWRDTRLSFLGPIRSLSLSIKMLER-IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDI 259
W D L + +I++ +WRPD YN + N ++R G I
Sbjct: 65 VWVDAHLKWNKDEYDGLDTIRIPSSYVWRPDIVLYNNADDHFTGPMDTNVVIR--HDGQI 122
Query: 260 LYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQ 319
+ K+ C +++ FP D Q C GS+ Y+ QL S + + +
Sbjct: 123 TWDSPAITKSSCRVDVSFFPFDAQQCRFTYGSWTYNGNQLDI-LNALDSADLADLVENVE 181
Query: 320 FDLISFPYRN--FTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIH 377
++++ P + + + + + LKR +++ + +PC++I L+ + F++
Sbjct: 182 WEILGMPAKKNVIQYGCCADPYPDVTYTLKLKRRASFYVFNLLIPCVMISFLAPLGFYLP 241
Query: 378 REVG 381
+ G
Sbjct: 242 ADSG 245
>UniRef50_Q66T35 Cluster: Nicotinic acetylcholine receptor subunit
alpha 3; n=7; Coelomata|Rep: Nicotinic acetylcholine
receptor subunit alpha 3 - Anopheles gambiae (African
malaria mosquito)
Length = 710
Score = 61.3 bits (142), Expect = 6e-08
Identities = 57/246 (23%), Positives = 107/246 (43%), Gaps = 21/246 (8%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF- 209
++LL NY P V+ + + + V+ + + + + Q W D +L +
Sbjct: 29 DDLLSNYNKLVRPVVNVTDALTVKIKLKLSQLIDVNLKNQIMTTNLWVEQTWYDYKLKWE 88
Query: 210 ---LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLT 266
G + L + + IWRPD YN +T+ K ++ G + +
Sbjct: 89 PKEYGGVEMLHVPS---DHIWRPDIVLYNNADGNFE-VTLATKAT-LNYTGRVEWRPPAI 143
Query: 267 IKAKCPMELRNFPMDRQSCPLILGSYAYSNQQL-VYQWQNSQSVNFVP-GMTLSQF---- 320
K+ C +++ FP D Q+C + GS+ Y Q+ + N V G+ LS+F
Sbjct: 144 YKSSCEIDVEYFPFDEQTCVMKFGSWTYDGFQVDLRHIDEMNETNVVEVGVDLSEFYTSV 203
Query: 321 --DLISFP-YRNFTFTRREGDFSVLQVSFN--LKRHTGYFLIQVYVPCILIVVLSWVSFW 375
D++ P RN F D L ++FN ++R T ++ + + +PC+ I L+ + F+
Sbjct: 204 EWDILEVPAVRNEKFYTC-CDEPYLDITFNITMRRKTLFYTVNLIIPCMGISFLTILVFY 262
Query: 376 IHREVG 381
+ + G
Sbjct: 263 LPSDSG 268
>UniRef50_A7RLM4 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 300
Score = 61.3 bits (142), Expect = 6e-08
Identities = 43/186 (23%), Positives = 84/186 (45%), Gaps = 8/186 (4%)
Query: 199 RQYWRDTRLSF-LGPIRSLSLSIKMLERIWRPDTYFYNGK-HSYVHTITVPNKLLRISQH 256
R+ W DT L++ L+ + E IWRPD YN + T N + ++
Sbjct: 45 RESWVDTSLAWNKSDFEGLAKIVLRPESIWRPDIVLYNNAGEDFGDGQTRTNAV--VTSD 102
Query: 257 GDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMT 316
G + ++ +K C ++ +P D+QSCP+I GS+ Y L + + S S +
Sbjct: 103 GLVSMTIPSILKTSCKIDATRYPFDKQSCPMIFGSWTYDGNLLSIKME-SHSADLSEYSE 161
Query: 317 LSQFDLISFP---YRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVS 373
++ L+S + + F + + +KR + Y+++ + +P + I +L+ +
Sbjct: 162 NVEWKLVSAEAKFHSKLFVCCPDTPFEEVTYTIVVKRRSLYYIMYLIIPAVAIALLTLLV 221
Query: 374 FWIHRE 379
F + E
Sbjct: 222 FLLPPE 227
>UniRef50_A7RJP2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 140
Score = 61.3 bits (142), Expect = 6e-08
Identities = 32/109 (29%), Positives = 59/109 (54%), Gaps = 2/109 (1%)
Query: 157 YENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSL 216
Y+ ++ P G P + +I + G + E++M+ + Y R W+D RL+ +++
Sbjct: 33 YDKTERPGVDTGKPVELGVDIHFDNFGRIEEMNMEVDVFLYMRYNWKDPRLANFTD-KTI 91
Query: 217 SLSIKMLERIWRPDTYFYNGKHSYVH-TITVPNKLLRISQHGDILYSMR 264
+ + +E++WRPDTY N + S + T + +LRI ++G I YS R
Sbjct: 92 TFTRGDIEKVWRPDTYCSNARESDLPLEETKTHSMLRIDRNGSIYYSRR 140
>UniRef50_A2TM50 Cluster: Nicotinic acetylcholine receptor alpha 4
subunit; n=4; Aphidinae|Rep: Nicotinic acetylcholine
receptor alpha 4 subunit - Sitobion avenae (English
grain aphid)
Length = 532
Score = 61.3 bits (142), Expect = 6e-08
Identities = 43/169 (25%), Positives = 82/169 (48%), Gaps = 14/169 (8%)
Query: 224 ERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQ 283
+ IW PD +N + +L+ + G++L+S K+ C + + FP D Q
Sbjct: 110 DHIWLPDIVLFNNADGNYEVTLMTKAVLKYT--GEVLWSPPAIYKSYCEINVLYFPFDEQ 167
Query: 284 SCPLILGSYAYSNQQL-VYQWQNSQSVNFVP-GMTLSQF------DLISFP-YRNFTFTR 334
+C ++ GS+ Y+ Q+ + SQ N V G+ LS+F DL+ P RN F
Sbjct: 168 NCYMMFGSWTYNGNQVDLRHIDQSQGRNRVDVGIDLSEFYLSVEWDLLEVPAVRNEEFYS 227
Query: 335 REGDFSVLQVSFNLK--RHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ S ++FN+K R T ++ + + +PC+ + ++ + ++ + G
Sbjct: 228 CCSE-SYTDITFNIKMRRKTLFYTVNLIIPCVGLTFMTVLVLYLPSDSG 275
>UniRef50_P43681 Cluster: Neuronal acetylcholine receptor subunit
alpha-4 precursor; n=35; Euteleostomi|Rep: Neuronal
acetylcholine receptor subunit alpha-4 precursor - Homo
sapiens (Human)
Length = 627
Score = 61.3 bits (142), Expect = 6e-08
Identities = 51/236 (21%), Positives = 98/236 (41%), Gaps = 6/236 (2%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L+ L Y P +V+ + I + V E + + + + +Q W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 209 FLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
+ SI++ E IWRPD YN +T K + G + ++
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNADGDF-AVTHLTKA-HLFHDGRVQWTPPAIY 157
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQ--LVYQWQNSQSVNFVPGMTLSQFDLISF 325
K+ C +++ FP D+Q+C + GS+ Y + LV ++F D +
Sbjct: 158 KSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVDAVG- 216
Query: 326 PYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y + + + +F ++R ++ I + +PC+LI L+ + F++ E G
Sbjct: 217 TYNTRKYECCAEIYPDITYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECG 272
>UniRef50_P17644 Cluster: Acetylcholine receptor subunit alpha-like
2 precursor; n=38; Neoptera|Rep: Acetylcholine receptor
subunit alpha-like 2 precursor - Drosophila melanogaster
(Fruit fly)
Length = 576
Score = 61.3 bits (142), Expect = 6e-08
Identities = 51/246 (20%), Positives = 105/246 (42%), Gaps = 20/246 (8%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF- 209
++LL NY P +V+ + + + ++ D + + + W+D + +
Sbjct: 50 DDLLSNYNRLIRPVSNNTDTVLVKLGLRLSQLIDLNLKDQILTTNVWLEHEWQDHKFKWD 109
Query: 210 ---LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLT 266
G + L + E IW PD YN T+ +L + G ++++
Sbjct: 110 PSEYGGVTELYVPS---EHIWLPDIVLYNNADGEYVVTTMTKAILHYT--GKVVWTPPAI 164
Query: 267 IKAKCPMELRNFPMDRQSCPLILGSYAYSNQQ--LVYQWQNSQSVNFVP-GMTLSQF--- 320
K+ C +++R FP D+Q+C + GS+ Y Q L + Q + N V G+ L ++
Sbjct: 165 FKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHISQKNDKDNKVEIGIDLREYYPS 224
Query: 321 ---DLISFPYRNFT--FTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFW 375
D++ P + + + + L+R T ++ + + +PC+ I LS + F+
Sbjct: 225 VEWDILGVPAERHEKYYPCCAEPYPDIFFNITLRRKTLFYTVNLIIPCVGISYLSVLVFY 284
Query: 376 IHREVG 381
+ + G
Sbjct: 285 LPADSG 290
>UniRef50_UPI0000E48474 Cluster: PREDICTED: similar to nicotinic
acetylcholine receptor subunit type G, partial; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
nicotinic acetylcholine receptor subunit type G, partial
- Strongylocentrotus purpuratus
Length = 452
Score = 60.9 bits (141), Expect = 8e-08
Identities = 47/195 (24%), Positives = 91/195 (46%), Gaps = 9/195 (4%)
Query: 193 SMDCYFRQYWRDTRLSFLGPIRSLSLSIKMLE--RIWRPDTYFYNGKHS--YVHTITVPN 248
+++ + Q+W D +L + P + I + IW PD Y+ S YV N
Sbjct: 8 TINVWIEQHWDDEKLVW-DPDAYEGIEILRIPATEIWLPDVTLYDNADSNDYVAHSRQSN 66
Query: 249 KLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQS 308
L+ D L+S +K+ C ++++ FP D Q C + GS+ Y++ Q+ +++++
Sbjct: 67 ALVNADGRVD-LWSKPALVKSTCKIDVKFFPFDEQMCSMKFGSWTYNSFQMSLD-KHTEA 124
Query: 309 VNFVPGMTLSQFDLISFPYR--NFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILI 366
+ + Q+DL R N + + + L+R Y++ + +PCIL+
Sbjct: 125 PDLSTFVNNEQWDLKFAVSRRHNVKYECCPERYHDVTFYIGLRRKPLYYIYNLIMPCILL 184
Query: 367 VVLSWVSFWIHREVG 381
LS + F++ +VG
Sbjct: 185 SSLSMLGFFMPYDVG 199
>UniRef50_A7RNN1 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 317
Score = 60.9 bits (141), Expect = 8e-08
Identities = 39/161 (24%), Positives = 68/161 (42%), Gaps = 5/161 (3%)
Query: 226 IWRPDTYFYNGKHSYVHTITVPNKL---LRISQHGDILYSMRLTIKAKCPMELRNFPMDR 282
+W PD YN + K + + G + T K+ C +++ FP D
Sbjct: 97 VWVPDIVLYNNGDPDLSLSGFTEKFKTFIILHSSGTCTWMSPTTFKSSCKLDITKFPFDS 156
Query: 283 QSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRNF--TFTRREGDFS 340
Q+C + GS+ Y N+ L + Q + + + L R + +T FS
Sbjct: 157 QTCSMTFGSWTYDNRLLSMDLLDKQYSHTERYVENGDWSLRKVETRRYLLNYTCCPHPFS 216
Query: 341 VLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ +F L R Y ++ + VPC++I LS V+F + + G
Sbjct: 217 DVTFTFYLDRKPTYHILYLIVPCVVIAALSVVNFLLPPDCG 257
>UniRef50_A7RLM5 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 317
Score = 60.9 bits (141), Expect = 8e-08
Identities = 47/210 (22%), Positives = 98/210 (46%), Gaps = 11/210 (5%)
Query: 172 VVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF----LGPIRSLSLSIKMLERIW 227
V++ ++++++ V E +M ++ + R W+D L + G + ++L IW
Sbjct: 32 VLRHGMMLKTIVAVEEKNMVFTTNVRLRMGWKDAFLQWNPADYGGVTQINLEAS---DIW 88
Query: 228 RPDTYFYNGKHSYVHTITVPNKLLRISQH-GDILYSMRLTIKAKCPMELRNFPMDRQSCP 286
P YN +IT N + + G +L+ + IK+ C ++++ FP D+Q C
Sbjct: 89 TPPVIIYNQAGDLGESITSSNTPRPVVRSDGTVLWMVPTVIKSSCVIDVKYFPFDQQLCK 148
Query: 287 LILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFP--YRNFTFTRREGDFSVLQV 344
+I GS+ Y +L Q + + V+ +T S++ L+S + + + +
Sbjct: 149 IIFGSWHYDVSKLDLQPLDGK-VDTTRYITNSEWKLLSATAVRTQVSHICCRQEVARITY 207
Query: 345 SFNLKRHTGYFLIQVYVPCILIVVLSWVSF 374
S +++R Y+ + +PC +I L + F
Sbjct: 208 SLHIERRRLYYSMNFILPCTIIAFLMLLVF 237
>UniRef50_Q15822 Cluster: Neuronal acetylcholine receptor subunit
alpha-2 precursor; n=98; Euteleostomi|Rep: Neuronal
acetylcholine receptor subunit alpha-2 precursor - Homo
sapiens (Human)
Length = 529
Score = 60.9 bits (141), Expect = 8e-08
Identities = 50/239 (20%), Positives = 105/239 (43%), Gaps = 12/239 (5%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+ ++L + Y P +V+ + I + V E + + + + +Q W D +L
Sbjct: 62 LFKHLFRGYNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLR 121
Query: 209 F----LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
+ G I SL + +M IW PD YN +T K S G + +
Sbjct: 122 WNPADFGNITSLRVPSEM---IWIPDIVLYNNADGEF-AVTHMTKAHLFST-GTVHWVPP 176
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLIS 324
K+ C +++ FP D+Q+C + GS+ Y ++ + Q Q+V+ ++ +++
Sbjct: 177 AIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLE-QMEQTVDLKDYWESGEWAIVN 235
Query: 325 F--PYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y + + + + +F ++R ++ I + +PC+LI L+ + F++ + G
Sbjct: 236 ATGTYNSKKYDCCAEIYPDVTYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCG 294
>UniRef50_UPI0001560C7D Cluster: PREDICTED: similar to cholinergic
receptor, nicotinic, alpha 2 (neuronal); n=2;
Laurasiatheria|Rep: PREDICTED: similar to cholinergic
receptor, nicotinic, alpha 2 (neuronal) - Equus caballus
Length = 630
Score = 60.5 bits (140), Expect = 1e-07
Identities = 51/239 (21%), Positives = 104/239 (43%), Gaps = 12/239 (5%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+ ++L + Y P +V+ + I + V E + + + + +Q W D +L
Sbjct: 60 LFKHLFRGYNRYARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLR 119
Query: 209 F----LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
+ G I SL + +M IW PD YN +T K S G + +
Sbjct: 120 WNPADFGNITSLRVPSEM---IWIPDIVLYNNADGEF-AVTHMTKAHLFST-GTVHWVPP 174
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLIS 324
K+ C +++ FP D+Q+C + GS+ Y ++ + Q Q+V+ ++ +I+
Sbjct: 175 AIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLE-QMEQTVDLKDYWESGEWAIIN 233
Query: 325 F--PYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y + + + + F ++R ++ I + +PC+LI L+ + F++ + G
Sbjct: 234 ATGTYNSKKYDCCAEIYPDVTYYFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCG 292
>UniRef50_UPI0000E47D8F Cluster: PREDICTED: similar to nicotinic
acetylcholine receptor alpha 7c subunit; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
nicotinic acetylcholine receptor alpha 7c subunit -
Strongylocentrotus purpuratus
Length = 257
Score = 60.5 bits (140), Expect = 1e-07
Identities = 44/200 (22%), Positives = 86/200 (43%), Gaps = 9/200 (4%)
Query: 186 SELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKMLE----RIWRPDTYFYNGKHSYV 241
+E++ +++ + + WRD FLG + I LE +IW PD Y
Sbjct: 18 NEMEQRITINGWRKLQWRD---EFLGWDKETYDGIDSLEVSPDKIWLPDIKLYENIDKDF 74
Query: 242 HTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVY 301
+ N L ++ G + + + I + C + +R FP D Q+C L GS+AY+ L
Sbjct: 75 QSEDAVNAL--VTNDGMVTWYTPMVISSSCKINVRYFPFDVQTCTLTFGSWAYTIDSLNL 132
Query: 302 QWQNSQSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYV 361
+ + + N + I + +S +++ L+R ++L + V
Sbjct: 133 NYSDDATQNVFLNNGVWDLRKIHLERITAKYDCCPFPYSSVKIDLFLERRYEFYLFNMVV 192
Query: 362 PCILIVVLSWVSFWIHREVG 381
PC+++ ++ + F + E G
Sbjct: 193 PCVMLSAINALVFLVPPESG 212
>UniRef50_UPI0000E47C58 Cluster: PREDICTED: similar to nicotinic
acetylcholine receptor beta 5 subunit; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
nicotinic acetylcholine receptor beta 5 subunit -
Strongylocentrotus purpuratus
Length = 477
Score = 60.5 bits (140), Expect = 1e-07
Identities = 46/212 (21%), Positives = 94/212 (44%), Gaps = 15/212 (7%)
Query: 179 IRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKMLER--IWRPDTYFYNG 236
+R++ + ++M + + W D L + P R ++ + R +W PD + YN
Sbjct: 39 VRNISQTTLVEMQFFVAQVLDVRWHDDYLVW-EPTRYNNVKNFKITRDDVWMPDLWLYNN 97
Query: 237 KHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSN 296
S + + + G +++ IK C M++ NFP D Q+C + G + +
Sbjct: 98 AGSRYEDYAA-HSICSVYHTGKVVWQSPTIIKTHCTMDVTNFPFDVQTCTVTFGPWQHGA 156
Query: 297 QQLVYQWQNSQSVNFVPGMTLSQFDLISF-------PYRNFTFTRREGDFSVLQVSFNLK 349
+++ S + S++++ SF PY+ + +S ++ S L+
Sbjct: 157 NEIMLNGTGSADKYL---RSSSEWEITSFRAKANQEPYQIY-LDDEPILYSYVEYSVFLR 212
Query: 350 RHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
R YF+ + +PC LI +++SF++ E G
Sbjct: 213 RIPTYFVFNLIMPCTLISATTFLSFFLPPESG 244
>UniRef50_A2TM48 Cluster: Nicotinic acetylcholine receptor alpha 1
subunit; n=3; Aphidinae|Rep: Nicotinic acetylcholine
receptor alpha 1 subunit - Sitobion avenae (English
grain aphid)
Length = 496
Score = 60.5 bits (140), Expect = 1e-07
Identities = 54/242 (22%), Positives = 106/242 (43%), Gaps = 23/242 (9%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF- 209
++LL NY P +V+ + + + ++ D + + + W D + +
Sbjct: 29 DDLLSNYNRLIRPVSNNTDTVLVKLGLRLSQLIELNLKDQILTTNVWLEHEWADHKFIWE 88
Query: 210 ---LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLT 266
G ++ L + E IW PD YN T+ +L S G ++++
Sbjct: 89 PLEYGGVKELYVPS---EHIWLPDIVLYNNADGEYVVTTMTKAVLHHS--GKVMWTPPAI 143
Query: 267 IKAKCPMELRNFPMDRQSCPLILGSYAYS----NQQLVYQWQNSQSVNFVPGMTLS-QFD 321
K+ C +++R FP D+Q+C + GS++Y N + + Q + V+ G+ LS +
Sbjct: 144 FKSSCEIDVRYFPFDQQTCFMKFGSWSYDGNLINLKHIGQLVGTNKVDV--GIDLSAYYP 201
Query: 322 LISFPYRNFTFTRREGDFS-----VLQVSFN--LKRHTGYFLIQVYVPCILIVVLSWVSF 374
+ + R E +S + + FN L+R T ++ + + VPC+ I LS + F
Sbjct: 202 SVEWDILGVPAGRHEKYYSCCVEPYIDIFFNITLRRRTLFYTVNLIVPCVGISYLSVLVF 261
Query: 375 WI 376
++
Sbjct: 262 YL 263
>UniRef50_Q7T2S3 Cluster: Nicotinic acetylcholine receptor alpha 4
subunit; n=2; Tetraodontidae|Rep: Nicotinic
acetylcholine receptor alpha 4 subunit - Fugu rubripes
(Japanese pufferfish) (Takifugu rubripes)
Length = 622
Score = 60.1 bits (139), Expect = 1e-07
Identities = 50/236 (21%), Positives = 100/236 (42%), Gaps = 6/236 (2%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L++L +Y P +V + I + V E + + + + +Q W D +L
Sbjct: 14 LLQDLFAHYNKLSRPVENTTDTVLVHFGLSIAQLIDVDEKNQMMTTNVWVKQEWNDYKLR 73
Query: 209 FLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
+ SI++ E IWRPD YN +T K ++ G I +
Sbjct: 74 WNPEEYENVTSIRIPSEIIWRPDIVLYNNADGDF-AVTHLTKA-QLFYDGRIKWMPPAIY 131
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQ--LVYQWQNSQSVNFVPGMTLSQFDLISF 325
K+ C +++ FP D+QSC + GS+ Y + L+ + +++ + +
Sbjct: 132 KSSCSIDVTFFPFDQQSCKMKFGSWTYDRAKIDLISMASDVDQMDYWESGEWVIVNAVG- 190
Query: 326 PYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y + +S + F ++R ++ I + +PC+LI L+ + F++ + G
Sbjct: 191 KYNTKKYECCTEIYSDITYYFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSQCG 246
>UniRef50_O62083 Cluster: Putative uncharacterized protein acr-19;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein acr-19 - Caenorhabditis elegans
Length = 554
Score = 59.7 bits (138), Expect = 2e-07
Identities = 50/235 (21%), Positives = 96/235 (40%), Gaps = 14/235 (5%)
Query: 153 LLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF--- 209
L +NY P + VV + + + + E + + + R W D L++
Sbjct: 32 LAENYNKLARPVRNESEAVVVLLGMDYQQILDIDEKHQIMNSNVWLRMSWTDHYLTWDPS 91
Query: 210 -LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIK 268
G I+ + L I IW+PD YN + N ++ + G++ + I+
Sbjct: 92 EFGNIKEVRLPIN---NIWKPDVLLYNSVDQQFDSTWPVNAVVLYT--GNVTWIPPAIIR 146
Query: 269 AKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYR 328
+ C +++ FP D Q C + GS+ YS + P +++L+ +
Sbjct: 147 SSCAIDIAYFPFDTQHCTMKFGSWTYSGFFTDLINTTISPATYKPN---GEWELLGLTSQ 203
Query: 329 NFTFTRREGDFSVLQVSF--NLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
F V+F +++R T Y+ + +PC+LI L+ +SF + + G
Sbjct: 204 RSIFFYECCPEPYYDVTFTVSIRRRTLYYGFNLLLPCMLISSLALLSFTLPADCG 258
>UniRef50_O46132 Cluster: Nicotinic acetylcholine receptor, alpha1
subunit; n=1; Locusta migratoria|Rep: Nicotinic
acetylcholine receptor, alpha1 subunit - Locusta
migratoria (Migratory locust)
Length = 559
Score = 59.7 bits (138), Expect = 2e-07
Identities = 54/234 (23%), Positives = 104/234 (44%), Gaps = 21/234 (8%)
Query: 163 PTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF----LGPIRSLSL 218
P Y V+ + + + V+ + + + + Q W D +L + G + +L +
Sbjct: 2 PVTNNSYRLTVKMGLRLSQLIDVNLKNQIMTTNVWVEQEWNDYKLKWNPDDYGGVDTLHV 61
Query: 219 SIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNF 278
E IW PD N +T+ K I G + + K+ C +++ F
Sbjct: 62 PS---EHIWLPDIVLTNNSEGNFE-VTLATKAT-IYHQGLVEWKPPAIYKSSCEIDVEYF 116
Query: 279 PMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFV--PGMTLSQF------DLISFP-YRN 329
P D Q+C L GS+ Y ++ + + Q+ + V G+ LS+F D++ P RN
Sbjct: 117 PFDEQTCVLKFGSWTYDGFKVDLRHMDEQAGSNVVEVGVDLSEFYMSVEWDILEVPAVRN 176
Query: 330 FTFTRREGDFSVLQVSFN--LKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
F D L ++FN ++R T ++ + + +PC+ I L+ ++F++ + G
Sbjct: 177 EKFYTC-CDEPYLDITFNITMRRKTLFYTVNIIIPCMGISFLTVLTFYLPSDSG 229
>UniRef50_A7S9T6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 321
Score = 59.7 bits (138), Expect = 2e-07
Identities = 54/236 (22%), Positives = 100/236 (42%), Gaps = 7/236 (2%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL 210
++L NY N P V +I M + E + + + R W D L++
Sbjct: 9 KHLFANYSNVVRPVKRVEEVVPVSFDIGYSQMVNLVEKNQILISNLWVRLKWYDPWLTWN 68
Query: 211 GPIRSLSLSIKMLER-IWRPDTYFYNG--KHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
SIK+ +W PD YN S K+ I G + + + +
Sbjct: 69 ESDFGGMKSIKVDPSCVWVPDIVLYNNVDSDSSGEMYKFTTKV-NIHSDGTVQWLSPIQV 127
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLIS--F 325
K++C +++ NFP+D Q C L GS+AY +L ++ + T ++ ++S
Sbjct: 128 KSECKIDITNFPLDEQFCKLEFGSWAYDGFELNLT-NARETADLSLYTTNGEWRMLSGKV 186
Query: 326 PYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ F E + L F+++R ++++ + +PC+L+ LS ++F E G
Sbjct: 187 TRKLSKFPCCEAPYITLIYMFHVQRRALFYVMNLIIPCVLLTFLSALTFRFPPESG 242
>UniRef50_Q4S3I6 Cluster: Chromosome 1 SCAF14749, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 1 SCAF14749, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 340
Score = 59.3 bits (137), Expect = 3e-07
Identities = 40/169 (23%), Positives = 73/169 (43%), Gaps = 8/169 (4%)
Query: 163 PTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKM 222
P + + + + V+E D + +C+ Q W D RL + I++
Sbjct: 29 PAVNNSQQVTIYIQVSLAQLIHVNERDQIMTTNCWLSQVWYDYRLMWNPEEYEGIKKIRL 88
Query: 223 -LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMD 281
+ IW PD YN N + IS +G++ + K+ C +E+R+FP D
Sbjct: 89 PTQHIWLPDIVLYNNADGTYEVSYYSNAV--ISNNGEVNWLPPAIYKSACKIEVRDFPFD 146
Query: 282 RQSCPLILGSYAYSNQQ--LVYQWQNSQSVNFVPGMTLSQFDLISFPYR 328
+Q+C L S+ Y + + L+ + +F P ++D++S P R
Sbjct: 147 QQNCTLQFRSWTYDHTEIDLILVSDYASRDDFKPS---GEWDIVSLPGR 192
>UniRef50_Q2XWL0 Cluster: Nicotinic acetylcholine receptor subunit
type C; n=1; Lymnaea stagnalis|Rep: Nicotinic
acetylcholine receptor subunit type C - Lymnaea
stagnalis (Great pond snail)
Length = 506
Score = 59.3 bits (137), Expect = 3e-07
Identities = 53/240 (22%), Positives = 107/240 (44%), Gaps = 24/240 (10%)
Query: 163 PTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKM 222
P+ G V+ + + + V E + ++ + RQ W D RL + P +++
Sbjct: 50 PSAGPMKKLTVKLGLRLSQVLSVDERNQILTISVWLRQEWYDFRLKW-EPSEYGGVNVLN 108
Query: 223 L--ERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPM 280
+ +++W+PD YN IT+ K + ++ G I++ K+ CP+++ FP
Sbjct: 109 IPSDQLWKPDLVLYNNADGDFQ-ITLKTKAI-VNHTGRIVWEPPAIYKSYCPIDVEYFPF 166
Query: 281 DRQSCPLILGSYAYSNQQLVYQW-----------QNSQSVNFVPGMTLSQ-FDLISFPYR 328
D Q C L + S+ Y +L Q Q+ ++ G+ L+ + + +
Sbjct: 167 DIQECFLKISSWTYHGHELDLQHLCKGIMSHEEDQDRANIIIPRGIDLTDYYKNVEWDVL 226
Query: 329 NFTFTRREGDFSVL-----QVSFN--LKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
N T RR + ++FN L+R T ++ + + +PC+ I L+ + F++ + G
Sbjct: 227 NVTAMRRVKFYPCCPEPYPDITFNITLRRRTLFYTLNLIMPCVSISCLTVLVFYLPSDSG 286
>UniRef50_P25162 Cluster: Acetylcholine receptor subunit beta-like 2
precursor; n=7; Diptera|Rep: Acetylcholine receptor
subunit beta-like 2 precursor - Drosophila melanogaster
(Fruit fly)
Length = 519
Score = 59.3 bits (137), Expect = 3e-07
Identities = 52/245 (21%), Positives = 100/245 (40%), Gaps = 19/245 (7%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF- 209
++LL NY P V + + + V+ + + + + +Q W D +L +
Sbjct: 35 DDLLSNYNRLIRPVVNNTETLTVWLGLKLSQLIEVNLKNQVMTTNLWVKQRWFDYKLRWD 94
Query: 210 ---LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLT 266
G + L + E IW PD YN + L+ + G++ +
Sbjct: 95 PEEYGGVEQLYVPS---EHIWVPDIVLYNNWDGNYEVTLMTKATLKYT--GEVFWEPPAI 149
Query: 267 IKAKCPMELRNFPMDRQSCPLILGSYAYSNQQL-VYQWQNSQSVNFVP-GMTLSQFDL-I 323
K+ C M + FP D Q C + GS+ Y+ Q+ + N V G+ L++F L +
Sbjct: 150 YKSSCEMNVEYFPYDEQICFMKFGSWTYNGAQVDLKHLDQIPGSNLVQVGIDLTEFYLSV 209
Query: 324 SFPYRNFTFTRRE-------GDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
+ T+ E FS + ++R T ++ + + VPC+ + L+ + F++
Sbjct: 210 EWDILEVPATKNEEYYPDTLEPFSDITFKLTMRRKTLFYTVNLIVPCVALTFLTVLVFYL 269
Query: 377 HREVG 381
+ G
Sbjct: 270 PSDSG 274
>UniRef50_UPI000058727F Cluster: PREDICTED: similar to Chain B,
Refined Structure Of The Nicotinic Acetylcholine
Receptor At 4a Resolution.; n=2; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to Chain B, Refined
Structure Of The Nicotinic Acetylcholine Receptor At 4a
Resolution. - Strongylocentrotus purpuratus
Length = 449
Score = 58.8 bits (136), Expect = 3e-07
Identities = 57/236 (24%), Positives = 102/236 (43%), Gaps = 9/236 (3%)
Query: 155 KNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL-GPI 213
++Y+ +++P+ G P V ++ ++S+ V+E WRD RL+++ G
Sbjct: 43 QDYDVTEIPSVGGINPLPVTVHLTLQSVKDVNEKKQGMVGTSTITVVWRDERLTWMSGHY 102
Query: 214 RSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKL-LRISQHGDILYSMRLTIKAKCP 272
++++ +W P N + P + + I G + L C
Sbjct: 103 GNITVLTLPCRLVWTPSIRLGNSNSEDSRILKNPEDIKVFIKNDGQVTLETNLLHSTACA 162
Query: 273 MELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRN-FT 331
M L FP D Q+C L++ S N +V + G +D+IS + +
Sbjct: 163 MNLALFPFDTQTCLLLITSLDLFNTSVVLV---PGVLKHRAGNRPLSWDVISMIHVSLLR 219
Query: 332 FTR-REGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIV 386
F + E FS L V+ L+R +++ + VP +L+ + VSF+I V SGE V
Sbjct: 220 FDQASEYAFSDLVVAIKLERLPHHYVFFIIVPVMLLNAVGIVSFFI--PVKSGERV 273
>UniRef50_Q7NDN8 Cluster: Glr4197 protein; n=1; Gloeobacter
violaceus|Rep: Glr4197 protein - Gloeobacter violaceus
Length = 359
Score = 58.8 bits (136), Expect = 3e-07
Identities = 45/210 (21%), Positives = 92/210 (43%), Gaps = 11/210 (5%)
Query: 170 PTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKMLE--RIW 227
P V T I + + + + ++ + W+D RL+F P+RS + +K E IW
Sbjct: 57 PLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAF-DPVRS-GVRVKTYEPEAIW 114
Query: 228 RPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPL 287
P+ F N +++ + + +S G + Y R + + P++ R +P D Q+ +
Sbjct: 115 IPEIRFVNVENARDADVVD----ISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQTLHI 170
Query: 288 ILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFP--YRNFTFTRREGDFSVLQVS 345
L + + +V + + V + L+ +D+ SF + F + S L
Sbjct: 171 YLIVRSVDTRNIVLA-VDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLESKLDYQ 229
Query: 346 FNLKRHTGYFLIQVYVPCILIVVLSWVSFW 375
+ R ++ + +P + I+ +SW +FW
Sbjct: 230 LRISRQYFSYIPNIILPMLFILFISWTAFW 259
>UniRef50_P54244 Cluster: Acetylcholine receptor subunit alpha-type
deg-3 precursor; n=2; Caenorhabditis|Rep: Acetylcholine
receptor subunit alpha-type deg-3 precursor -
Caenorhabditis elegans
Length = 564
Score = 58.8 bits (136), Expect = 3e-07
Identities = 47/211 (22%), Positives = 88/211 (41%), Gaps = 9/211 (4%)
Query: 173 VQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL-GPIRSLSLSIKMLERIWRPDT 231
V +I + + V E + ++ + Q WRD L + ++ +I +W PDT
Sbjct: 80 VHISISLYQIIEVDEPSQNIKLNVWMIQKWRDEYLDWNPNEYGMINSTIIPFHHLWIPDT 139
Query: 232 YFYNG-KHSYVHT-----ITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSC 285
Y YN K S T I + + + ++ + C + +R FP DRQ+C
Sbjct: 140 YLYNSVKMSRDETERYMNIQATSNYWKGEKGAELSFLYPAIYTITCRLNIRFFPYDRQNC 199
Query: 286 PLILGSYAYSNQQLVYQWQNSQSV-NFVPGMTLSQFDLISFPYRNFTFTRREGDFSVLQV 344
L + S+ S L Y S+ +F+P Q + + + +LQ
Sbjct: 200 TLTISSWTNSKSALDYYADTEVSMQSFIPNEEW-QVKSFKIHRHEYKYACCAEPWVILQA 258
Query: 345 SFNLKRHTGYFLIQVYVPCILIVVLSWVSFW 375
S ++R Y+L+ + +P +I +++ F+
Sbjct: 259 SLVIQRKPLYYLVNLIIPTSIITLVAITGFF 289
>UniRef50_Q4S3I4 Cluster: Chromosome 1 SCAF14749, whole genome
shotgun sequence; n=2; Euteleostomi|Rep: Chromosome 1
SCAF14749, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 503
Score = 58.4 bits (135), Expect = 4e-07
Identities = 51/237 (21%), Positives = 104/237 (43%), Gaps = 8/237 (3%)
Query: 148 SVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRL 207
++L NL + Y+ P V+ + I + V E + + + + Q W D +L
Sbjct: 14 ALLRNLFQGYQRWVRPIQHANDTIKVRFGLKISQLVDVDEKNQLMTTNVWLCQEWIDYKL 73
Query: 208 SFLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLT 266
+ SI++ E +W PD Y + ++R + G I ++ +
Sbjct: 74 RWNPDKYGGITSIRVPSENLWLPDIVLYENADGRFEGSLMTKAIVRYN--GAITWTPPAS 131
Query: 267 IKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFP 326
K+ C M++ FP DRQ+C + GS+ Y + + Q V+ +++++S
Sbjct: 132 YKSACTMDVTFFPFDRQNCTMKFGSWTYDGTMVDLILIDKQ-VDRKDFFDNGEWEILS-- 188
Query: 327 YRNFTFTRREGDFS--VLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
R++G +S + SF LKR ++ + + +PC+ + L+ + F++ + G
Sbjct: 189 ATGAKGNRKDGLYSYPFITYSFILKRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEG 245
>UniRef50_Q67X94 Cluster: Putative uncharacterized protein lgc-2;
n=3; Caenorhabditis|Rep: Putative uncharacterized
protein lgc-2 - Caenorhabditis elegans
Length = 509
Score = 58.4 bits (135), Expect = 4e-07
Identities = 60/298 (20%), Positives = 126/298 (42%), Gaps = 17/298 (5%)
Query: 85 RHTPKILSAAKNTSRDTAEPDYWDNINEI--MFSNYANSSFEQTDVFTWKQNKRSINDAV 142
+H L +K + T E Y+D+ E + N+ N+ E ++ + +
Sbjct: 8 QHLLTFLILSKINATSTTE-SYFDSSEEAPNVLLNHLNNESEGEELTQINDTQPAFVPGS 66
Query: 143 SKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYW 202
SK +T E LL + N P G Y V L+ +G + EL ++ Y ++W
Sbjct: 67 SKRLT---EYLLSRH-NLNAPPDGLLY--VEYELELVHILG-IDELKQTMTVLIYVDEHW 119
Query: 203 RDTRLSFLGPI-RSLSLSIKMLERIWRPDTYFYN----GKHSYVHTITVPNKLLRISQHG 257
D L++ + ++ + L++IW PD +N + ++ ++ RI +G
Sbjct: 120 VDPSLTWDPALFGGITKTWIPLDKIWVPDIIVFNMVKSNRLAHEDLLSAVRAPARIHYNG 179
Query: 258 DILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTL 317
I+ S C + +R+FP+D Q C + + S+AY +++ S+
Sbjct: 180 TIVASHPAVHTVSCEINIRHFPLDDQRCAIEIASWAYGQEKIRLHAHTDHSLEHY--KRN 237
Query: 318 SQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFW 375
++ L++ + + S ++ +LKR ++++ + P ++ +S V +
Sbjct: 238 EEWHLLNLNVSEEKYEHEGVEVSEVKFEISLKRRPLFYMVTLTFPSYIMCAISVVGLF 295
>UniRef50_Q4RLA7 Cluster: Chromosome 21 SCAF15022, whole genome
shotgun sequence; n=5; Clupeocephala|Rep: Chromosome 21
SCAF15022, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 592
Score = 58.0 bits (134), Expect = 6e-07
Identities = 39/160 (24%), Positives = 72/160 (45%), Gaps = 7/160 (4%)
Query: 224 ERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQ 283
++IW PD YN + N L+ S + + Y + C +++R FP D Q
Sbjct: 123 DQIWTPDILLYNSADDDFDSTFKTNVLVNSSGYAE--YQPPGIFMSTCNVDVRWFPFDIQ 180
Query: 284 SCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFP-YRNFTF-TRREGDFSV 341
C L GS+ Y L Q N+ ++P ++DLI P R+ F + +
Sbjct: 181 RCELKFGSWTYDGWLLDLQMNNADISGYMPN---GEWDLIGVPGTRSEVFYDCCQEPYPA 237
Query: 342 LQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ ++R T Y+ + + +PC+L+ ++ + F + + G
Sbjct: 238 VTFVVAIRRRTLYYALNLLIPCVLLSSMTLLIFVLPADSG 277
>UniRef50_P54246 Cluster: Acetylcholine receptor subunit alpha-type
acr-5 precursor; n=3; Caenorhabditis|Rep: Acetylcholine
receptor subunit alpha-type acr-5 precursor -
Caenorhabditis elegans
Length = 548
Score = 58.0 bits (134), Expect = 6e-07
Identities = 67/296 (22%), Positives = 125/296 (42%), Gaps = 18/296 (6%)
Query: 96 NTSRDTAEPDYWDNINEIMFSNYA--NSSFEQTDVFTWKQNKRSINDAVSKNITS-VLEN 152
+T +T D+ + + + + A N++F Q + ++ +N+ N ++E
Sbjct: 51 STRNNTNVDDFQTQLKKSLENTTAAYNATFMQELIEERQRYLEKLNEGQFINDQRRLVEE 110
Query: 153 LL--KNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL 210
LL YE + P PT V ++ + + V E ++ + Q+W D L +
Sbjct: 111 LLDPNYYEKTVHPKRDYTRPTRVNLSMSLYQILDVDEHMQSIEVNVWMVQHWYDEFLDW- 169
Query: 211 GPIR--SLSLSIKMLERIWRPDTYFYNGKH-SYVHTITVPNKLLRI---SQHGD---ILY 261
P+ ++ +I +IW PDTY YN + T ++ N L +Q D +
Sbjct: 170 NPVDYGMINRTIVPYHQIWIPDTYLYNSEELEQKKTESLMNAQLETGHWNQKKDGAKVQL 229
Query: 262 SMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFD 321
K C M++R FP DRQ+ Q + Y W S +VN +++
Sbjct: 230 MFPAIYKLSCRMDVRWFPYDRQNYKTSFKPMKLLQQTIDY-WPLSSTVNLGNMARNDEWE 288
Query: 322 LISFPYRNF--TFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFW 375
+ISF + TF + +L ++R Y++I + VP +I +++ F+
Sbjct: 289 VISFEFVRVEETFKCCTAPWVMLYAHLVIRRKPLYYMINLVVPTSIITIVAVTGFF 344
>UniRef50_UPI0000E464AB Cluster: PREDICTED: similar to nicotinic
acetylcholine receptor; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to nicotinic
acetylcholine receptor - Strongylocentrotus purpuratus
Length = 528
Score = 57.6 bits (133), Expect = 8e-07
Identities = 46/193 (23%), Positives = 84/193 (43%), Gaps = 15/193 (7%)
Query: 197 YFRQYWRDTRLSF----LGPIRSLSLSIKMLERIWRPDTYFYNGKH-SYVHTITVPNKLL 251
+ RQ W D RL + G I + + I +L W+PD YN SY T+ +
Sbjct: 67 WVRQRWEDYRLVWDPADYGNITMVHIPIFLL---WKPDIVLYNNVGGSYAITMLT---MT 120
Query: 252 RISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNF 311
++ +G + + ++ CP+ + +FP D Q CPL GS+ + ++ Q S+ V
Sbjct: 121 QVYPNGTVDWFPPAVYRSSCPINIHDFPFDEQRCPLKFGSWTHDYSKIDLQ-PISEFVGL 179
Query: 312 VPGMTLSQFDLISFPYRNFTFTRREGD---FSVLQVSFNLKRHTGYFLIQVYVPCILIVV 368
++D+ P D + L +F L R + ++++ +PC +I
Sbjct: 180 ERFWENQEWDIAETPIERHKLQYPCCDTETYVDLTFTFVLHRKSLFYVVTFVLPCCMIAF 239
Query: 369 LSWVSFWIHREVG 381
L+ F++ G
Sbjct: 240 LTIFVFYVPSNCG 252
>UniRef50_UPI0000E45D33 Cluster: PREDICTED: similar to nicotinic
acetylcholine receptor subunit alpha 6; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
nicotinic acetylcholine receptor subunit alpha 6 -
Strongylocentrotus purpuratus
Length = 440
Score = 57.6 bits (133), Expect = 8e-07
Identities = 57/262 (21%), Positives = 102/262 (38%), Gaps = 15/262 (5%)
Query: 132 KQNKRSINDAVS--KNITSVLE---NLLKNY-ENSQLPTHGKGYPTVVQTNILIRSMGPV 185
K ++ +N +S NIT+ E NLL Y + S P P V +L+ + +
Sbjct: 16 KAHRVDVNTTLSAESNITTEKELVANLLSEYGDTSVRPVKDHLQPVEVFFRMLLFELITL 75
Query: 186 SELDMDYSMDCYFRQYWRDTRLSF----LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYV 241
E ++ R W D L + G I +++L ++WRPD
Sbjct: 76 DETHQMVTVRSNMRLQWTDEYLQWDPDENGGIYNITLKTN---QVWRPDVVLDEDLDRDF 132
Query: 242 HTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVY 301
+I + + + G + + + C M ++ FP D Q C L + ++ +
Sbjct: 133 ISIPEADTFVIVQYTGAMDWLFPAITTSACKMNIQYFPFDTQQCVLTFYPWTLDESKMRF 192
Query: 302 QWQNSQSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLK--RHTGYFLIQV 359
+N + + + + F NF+F + + + L R G+FL +
Sbjct: 193 FAKNDEDALQARYVRNGIWSMTDFKPENFSFRYICCPYPNDHIRYTLTFDREYGFFLSNI 252
Query: 360 YVPCILIVVLSWVSFWIHREVG 381
VP I + L V FW+H + G
Sbjct: 253 IVPAIFLTSLMLVGFWLHPDSG 274
>UniRef50_Q2XWK8 Cluster: Nicotinic acetylcholine receptor subunit
type E; n=16; Protostomia|Rep: Nicotinic acetylcholine
receptor subunit type E - Lymnaea stagnalis (Great pond
snail)
Length = 538
Score = 57.6 bits (133), Expect = 8e-07
Identities = 47/223 (21%), Positives = 94/223 (42%), Gaps = 15/223 (6%)
Query: 172 VVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF-LGPIRSLSLSIKMLERIWRPD 230
VV+ I + + + E + + + + RQ W D +L++ + E IW PD
Sbjct: 58 VVKMGIRLSQLIDIDEKNQIMTTNVWLRQEWTDKKLTWQASEYGGVDHLYVPSEHIWLPD 117
Query: 231 TYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILG 290
YN + +T+ K + G +++ K+ C + + FP D QSC + G
Sbjct: 118 IVLYNNADGN-YEVTLMTKAT-VHSTGLVVWEPPAIYKSSCTINVEFFPFDEQSCKMKFG 175
Query: 291 SYAYSNQQL----VYQWQNSQSVNFVPGMTLSQF------DLISF-PYRNF-TFTRREGD 338
S+ Y Q+ + N +V G+ L F D++ +N +
Sbjct: 176 SWTYDGDQVDLVHICAKSNEANVTIKNGIDLRDFYPSVEWDILEVDAVKNIRQYPCCTER 235
Query: 339 FSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ + S +++R T + + + +PC+ I L+ + F++ + G
Sbjct: 236 YPDITFSVSMRRKTLFHTVNLIIPCVAISCLTVLVFYLPSDSG 278
>UniRef50_P91197 Cluster: Acetylcholine receptor protein 11; n=2;
Caenorhabditis|Rep: Acetylcholine receptor protein 11 -
Caenorhabditis elegans
Length = 461
Score = 57.6 bits (133), Expect = 8e-07
Identities = 48/245 (19%), Positives = 102/245 (41%), Gaps = 13/245 (5%)
Query: 147 TSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTR 206
T + +LLK Y + P P V+ + ++ + V E + S++ + W D +
Sbjct: 27 TKLFTDLLKGYNPLERPVQNSSQPLEVKIKLFLQQILDVDEKNQIVSVNAWLSYTWFDHK 86
Query: 207 LSF----LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYS 262
L + G I+ + + IW+PD YN + T + LL G +++
Sbjct: 87 LQWEPKKYGGIQDIRFPGSS-DHIWKPDVLLYNSAAEDFDS-TFKSNLLTYHT-GTVVWI 143
Query: 263 MRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQ----WQNSQSVNFVPGMTLS 318
+K C +++ FP D Q C + GS+ + + Q +QS++ +
Sbjct: 144 PPGVLKFVCQLDVTWFPFDDQVCEMKFGSWTFHGYAIDLQIDDDTNGTQSMDLSTYLVNG 203
Query: 319 QFDLISFPYRNFT--FTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
++ +IS + + + + +++R T Y+ + +P +LI +++ + F
Sbjct: 204 EWQVISTNAKRVVSYYKCCPEPYPTVNYYLHIRRRTLYYGFNLIIPSLLISLMAILGFMF 263
Query: 377 HREVG 381
+ G
Sbjct: 264 PPDAG 268
>UniRef50_O44452 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 464
Score = 57.6 bits (133), Expect = 8e-07
Identities = 49/235 (20%), Positives = 97/235 (41%), Gaps = 8/235 (3%)
Query: 139 NDAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYF 198
+D + T ++E + + Y+ P P +V I++ + V E S
Sbjct: 34 DDYIKTEPTHLIETIQRRYDKRVRPFAESNRPVIVHMTIVLGILTEVRENQQVASFVISH 93
Query: 199 RQYWRDTRLSFLGPIRSLSLSIKMLER--IWRPDTYFYNGKHSYVHTITVPNKLLRISQH 256
Q WRD +L++ P L+ ++ R +W P + YN + +T +RI
Sbjct: 94 VQKWRDPKLAW-NPADHSGLTQVVMPRSLVWVPKLFIYNSMDTK-DMLTDDRYDVRIQHT 151
Query: 257 GDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMT 316
G + + + C + + FP D Q C + L S S +++ ++ G
Sbjct: 152 GHVKVNSPQFVSTLCRINIDLFPFDTQFCAIALASPLLSVEEMDVNATQPPVDSYFSGN- 210
Query: 317 LSQFDLISFPYRNFTFTRREGDF-SVLQVSFNLKRHTGYFLIQVYVPCILIVVLS 370
+++ +++ + F EG++ + + +L R Y++ + VP LI LS
Sbjct: 211 -AEWQVMNVTVKQMKF-MEEGEYRAEVHYILHLNRRPTYYITVIVVPTFLISALS 263
>UniRef50_Q66T21 Cluster: Nicotinic acetylcholine receptor subunit
alpha 9; n=4; Culicidae|Rep: Nicotinic acetylcholine
receptor subunit alpha 9 - Anopheles gambiae (African
malaria mosquito)
Length = 406
Score = 57.2 bits (132), Expect = 1e-06
Identities = 52/234 (22%), Positives = 100/234 (42%), Gaps = 8/234 (3%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL 210
++LLK Y+ S P+ T V+T I I + ++E+ S+ + + W D +L++
Sbjct: 44 KDLLKGYDPSIRPSQHYNV-TTVETGITITHV-EINEIKSTLSVYGWMKFSWNDPKLTW- 100
Query: 211 GPIRSLSLSIKMLER--IWRPDTYFYNGKH-SYVHTITVPNKLLRISQHGDILYSMRLTI 267
P +L++ + +WRPD YN S H N L + G +L+
Sbjct: 101 NPASYGNLNVVRWDPTIVWRPDVVLYNNAGGSDQHHYGDTNVL--VYSEGKVLWVPPTEY 158
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPY 327
A C + +R +P D Q C + +GS+ + L + + + + + IS
Sbjct: 159 HAFCELNMRLWPFDYQKCIVKIGSWTFDGYMLNLTIGSEPQIETLVSNSEWKIAKISVER 218
Query: 328 RNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ + + + L+R + V VP ++I++L+ FW+ + G
Sbjct: 219 NTRYYPCCTEPYIDITYNVTLQRQSDTHRAIVIVPALVIMILALSVFWLPLDAG 272
>UniRef50_P30532 Cluster: Neuronal acetylcholine receptor subunit
alpha-5 precursor; n=70; Euteleostomi|Rep: Neuronal
acetylcholine receptor subunit alpha-5 precursor - Homo
sapiens (Human)
Length = 468
Score = 57.2 bits (132), Expect = 1e-06
Identities = 49/246 (19%), Positives = 110/246 (44%), Gaps = 13/246 (5%)
Query: 141 AVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQ 200
+++K+ S+L++L ++YE P ++ + I + V E + + + + +Q
Sbjct: 42 SIAKHEDSLLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQ 101
Query: 201 YWRDTRLSFLGPIRSLSLSIKML--ERIWRPDTYFYN---GKHSYVHTITVPNKLLRISQ 255
W D +L + P + + + + +W PD ++ G+ T TV I
Sbjct: 102 EWIDVKLRW-NPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTV------IRY 154
Query: 256 HGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGM 315
+G + ++ K+ C +++ FP D Q+C + GS+ Y Q+ ++ Q V+
Sbjct: 155 NGTVTWTPPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILED-QDVDKRDFF 213
Query: 316 TLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFW 375
+++++S T + + SF +KR ++ + + +PCI + L+ + F+
Sbjct: 214 DNGEWEIVSATGSKGNRTDSCCWYPYVTYSFVIKRLPLFYTLFLIIPCIGLSFLTVLVFY 273
Query: 376 IHREVG 381
+ G
Sbjct: 274 LPSNEG 279
>UniRef50_Q2XWK3 Cluster: Nicotinic acetylcholine receptor subunit
type K; n=1; Lymnaea stagnalis|Rep: Nicotinic
acetylcholine receptor subunit type K - Lymnaea
stagnalis (Great pond snail)
Length = 501
Score = 56.8 bits (131), Expect = 1e-06
Identities = 57/261 (21%), Positives = 113/261 (43%), Gaps = 25/261 (9%)
Query: 140 DAVSKNIT-----SVLENLLKNYENSQL---PTHGKGYPTVVQTNILIRSMGPVSELDMD 191
D +KNI +++NLL Y+ P + N+ + + + E +
Sbjct: 17 DGFNKNIQLSEEDKLIKNLLARYKRRGTYARPVKEYNDSITINFNMQLIQIMDLDEKNQV 76
Query: 192 YSMDCYFRQYWRDTRLSFLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKL 250
+++ + R W D L++ +I++ +IW PD YN Y +
Sbjct: 77 LTLNVWDRYIWHDLHLTWNETKHGGVKNIRVPSNKIWIPDLKLYN----YADERLAERRD 132
Query: 251 LR--ISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQS 308
R + +G +L+ + K+ C +++ FP D Q+C L GS+ ++ + +
Sbjct: 133 ARCVVESNGKVLWMPQAIYKSSCEIDVATFPFDIQNCTLKFGSWTHNGNLIDLMVLSMDG 192
Query: 309 VNFVPG-MTLSQF------DLISFP-YRNFTFTRREGDFSVLQVSFNL--KRHTGYFLIQ 358
G + +SQF +++++P +N F D + +SF + +R + ++
Sbjct: 193 ETGENGSIDMSQFVKSNSWEIMAYPAKKNKQFYTCCPDEPYIDLSFTIVFRRRSTFYNYI 252
Query: 359 VYVPCILIVVLSWVSFWIHRE 379
+ +PCIL+ L+ V FWI E
Sbjct: 253 LILPCILLTSLTLVLFWIPPE 273
>UniRef50_A7S9T8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 390
Score = 56.8 bits (131), Expect = 1e-06
Identities = 44/191 (23%), Positives = 88/191 (46%), Gaps = 7/191 (3%)
Query: 197 YFRQYWRDTRLSFLGPIRSLSLSIKMLER--IWRPDTYFYNGKHSYVHTIT-VPNKLLRI 253
+ RQ W D L + P + ++ ++ +W+PD YN + + N + I
Sbjct: 12 WVRQTWTDAWLKW-DPAKHGGITAINVDPSFLWKPDMVLYNNVNDEDRGEQYLFNTKVII 70
Query: 254 SQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQL-VYQWQNSQSVNFV 312
GDI + +K C ++++ FP D Q+C L GS+ Y+ ++ V ++ +
Sbjct: 71 YSTGDIEWYSPNILKTHCKIDIQYFPFDTQTCKLTFGSWTYNGLKIDVTFFRGIAGADIS 130
Query: 313 PGMTLSQFDLISF-PYRNFT-FTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLS 370
+++L+S RN ++ + L +KR + +++ + +PCIL+ +L+
Sbjct: 131 TYSQNGEWELVSADAVRNVVKYSCCPEPYQDLTYKIKIKRRSMFYVNNLILPCILLALLT 190
Query: 371 WVSFWIHREVG 381
+SF E G
Sbjct: 191 GLSFLFPPETG 201
>UniRef50_P04755 Cluster: Acetylcholine receptor subunit beta-like 1
precursor; n=20; Protostomia|Rep: Acetylcholine receptor
subunit beta-like 1 precursor - Drosophila melanogaster
(Fruit fly)
Length = 521
Score = 56.8 bits (131), Expect = 1e-06
Identities = 48/248 (19%), Positives = 104/248 (41%), Gaps = 12/248 (4%)
Query: 141 AVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQ 200
+ S++ ++ +L + Y P V+ + + V+E + + + R
Sbjct: 23 SASEDEERLVRDLFRGYNKLIRPVQNMTQKVGVRFGLAFVQLINVNEKNQVMKSNVWLRL 82
Query: 201 YWRDTRLSF----LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQH 256
W D +L + G I L L +++W+PD +N N L I
Sbjct: 83 VWYDYQLQWDEADYGGIGVLRLPP---DKVWKPDIVLFNNADGNYEVRYKSNVL--IYPT 137
Query: 257 GDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQL-VYQWQNSQSVNFVPGM 315
G++L+ ++ C +++ FP D+Q+C + GS+ ++ Q+ + + N V+
Sbjct: 138 GEVLWVPPAIYQSSCTIDVTYFPFDQQTCIMKFGSWTFNGDQVSLALYNNKNFVDLSDYW 197
Query: 316 TLSQFDLISFPYRNFTFTRREGDFSVLQVSFN--LKRHTGYFLIQVYVPCILIVVLSWVS 373
+D+I P + + ++F ++R T ++ + + +P +LI L +
Sbjct: 198 KSGTWDIIEVPAYLNVYEGDSNHPTETDITFYIIIRRKTLFYTVNLILPTVLISFLCVLV 257
Query: 374 FWIHREVG 381
F++ E G
Sbjct: 258 FYLPAEAG 265
>UniRef50_Q2XWL2 Cluster: Nicotinic acetylcholine receptor subunit
type A; n=1; Lymnaea stagnalis|Rep: Nicotinic
acetylcholine receptor subunit type A - Lymnaea
stagnalis (Great pond snail)
Length = 485
Score = 56.4 bits (130), Expect = 2e-06
Identities = 51/238 (21%), Positives = 102/238 (42%), Gaps = 7/238 (2%)
Query: 149 VLENLLK--NYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTR 206
VL+ L + +Y + P + P V I+++ + V E + + + R W
Sbjct: 29 VLKKLFEESDYNKFERPILNESEPINVNFGIILQQIIDVDEKNQIIHTNIWLRMTWNAAN 88
Query: 207 LSFLGPIRSLSLSIKMLER-IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRL 265
L + SI++ ++ +W PD YN T P ++ I+ +G+ L+
Sbjct: 89 LMWDPKEYGNLTSIRVPKQMVWVPDILLYNSASDGFDD-TYPTNVV-INYNGNCLWVPPG 146
Query: 266 TIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISF 325
K+ C +++ FP D Q C L GS+ + L + + + ++ L+
Sbjct: 147 MFKSTCAIDITWFPFDDQRCNLKYGSWTHEGHLLNLTADSDDGGDISTFIRNGEWMLLGV 206
Query: 326 PY-RNF-TFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
P RN ++ + L + +++R T Y+ + +PC+LI L+ + F + + G
Sbjct: 207 PVTRNVQSYDCCPEVYIDLTFTIHIRRRTLYYGFNIIIPCVLISSLTLLLFILPPDAG 264
>UniRef50_P48180 Cluster: Acetylcholine receptor subunit alpha-type
acr-16 precursor; n=3; Caenorhabditis|Rep: Acetylcholine
receptor subunit alpha-type acr-16 precursor -
Caenorhabditis elegans
Length = 498
Score = 56.4 bits (130), Expect = 2e-06
Identities = 46/234 (19%), Positives = 97/234 (41%), Gaps = 6/234 (2%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL 210
E+L++NY N + P P V + ++ + V E + ++ + W D L +
Sbjct: 28 EDLMRNYNNLERPVANHSEPVTVHLKVALQQIIDVDEKNQVVYVNAWLDYTWNDYNLVWD 87
Query: 211 GPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKA 269
++ +IW+PD YN + + N + + G + + K
Sbjct: 88 KAEYGNITDVRFPAGKIWKPDVLLYNSVDTNFDSTYQTNMI--VYSTGLVHWVPPGIFKI 145
Query: 270 KCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDL-ISFPYR 328
C ++++ FP D Q C GS+ Y +L Q + + ++ ++ L ++ R
Sbjct: 146 SCKIDIQWFPFDEQKCFFKFGSWTYDGYKLDLQ-PATGGFDISEYISNGEWALPLTTVER 204
Query: 329 NFTF-TRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
N F + + +++R T Y+ + +PCIL +++ + F + + G
Sbjct: 205 NEKFYDCCPEPYPDVHFYLHMRRRTLYYGFNLIMPCILTTLMTLLGFTLPPDAG 258
>UniRef50_UPI0000E49D12 Cluster: PREDICTED: similar to acetylcholin
receptor alpha subunit 1A; n=2; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to acetylcholin
receptor alpha subunit 1A - Strongylocentrotus
purpuratus
Length = 462
Score = 56.0 bits (129), Expect = 2e-06
Identities = 50/252 (19%), Positives = 99/252 (39%), Gaps = 8/252 (3%)
Query: 136 RSINDAVSKNITS--VLENLLKNY-ENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDY 192
R N ++ N T+ +++ L Y + S P + T V +LI + +E
Sbjct: 31 RQSNTGLTNNSTTKALVKKLTDGYGDTSVRPVYNYRQTTYVYLRMLIYELVAFNEHSQHI 90
Query: 193 SMDCYFRQYWRDTRLSFLGPIRSLSLSIKMLER-IWRPDTYFYNGKHSYVHTITVPNKLL 251
++ + WRD L + S+ + IW+PD + VH I ++
Sbjct: 91 TLRSNMKMTWRDEYLQWDPSEWDGITSVTLRPSDIWKPD-FDLEQNVERVHFIVADTYVI 149
Query: 252 RISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNF 311
G + + + C + + FP D Q C + + N Q+ ++ +
Sbjct: 150 A-DYTGTVRWIFPVITTTACKINIVYFPYDVQQCNVTFYPWTLDNSQMRLLAEDDDDAHQ 208
Query: 312 VPGMTLSQFDLISFPYRNFTFTRR--EGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVL 369
+ +DL +F N + + F + + +L R +F Q+ +P + + +L
Sbjct: 209 QMYIRNGVWDLTNFQAANESIPYKCCPHPFDHVVYTLDLAREAAFFTTQIVMPSVFLSIL 268
Query: 370 SWVSFWIHREVG 381
+SFW+H + G
Sbjct: 269 MLISFWLHPDSG 280
>UniRef50_UPI00006A0062 Cluster: UPI00006A0062 related cluster; n=1;
Xenopus tropicalis|Rep: UPI00006A0062 UniRef100 entry -
Xenopus tropicalis
Length = 457
Score = 56.0 bits (129), Expect = 2e-06
Identities = 41/161 (25%), Positives = 69/161 (42%), Gaps = 10/161 (6%)
Query: 226 IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSC 285
+WRPD Y Y + + L+I +G + S L I C M+ FP D Q+C
Sbjct: 109 VWRPDLYIYEMVDDDDKSPKI--NYLKIYYNGIVTNSKPLRIAGSCSMQNFKFPFDEQNC 166
Query: 286 PLILGSYAYSNQQLVYQWQNSQSVNFVPG-----MTLSQFDLISFPYRNFTFTRREGDFS 340
L GSY Y++ + VY S S T + L++ RN G+F+
Sbjct: 167 SLTFGSYVYNDFE-VYMMAASNSSQVTENSKDIFRTKGDWILLNIIVRNNPLP--SGNFN 223
Query: 341 VLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ ++KR+ ++ + +P +V+L S ++ G
Sbjct: 224 RVTYEIHIKRNPIIYVFNLILPACFLVILDIASMFMEGTEG 264
>UniRef50_Q6TMY3 Cluster: Nicotinic acetylcholine receptor alpha
subunit precursor; n=4; Schistosoma|Rep: Nicotinic
acetylcholine receptor alpha subunit precursor -
Schistosoma haematobium (Blood fluke)
Length = 714
Score = 56.0 bits (129), Expect = 2e-06
Identities = 43/168 (25%), Positives = 74/168 (44%), Gaps = 14/168 (8%)
Query: 226 IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSC 285
+WRPD YN T P + I G + + K+ C +++ FP D QSC
Sbjct: 113 VWRPDILLYNCADEKFDR-TFPTNTI-IKHDGTVQWMPPGLFKSTCNIDILWFPFDEQSC 170
Query: 286 PLILGSYAYSNQQLVYQWQ----NSQSVNFVPGMTLS------QFDLISFPYRNFT--FT 333
L GS+ Y Q+ +Q Q + V + LS +F L R + +
Sbjct: 171 ILKFGSWTYYGDQINFQLQCINASQPDCTQVGTVDLSEYSRNGEFHLSGSSVRRYAQRYE 230
Query: 334 RREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ DF ++++ L+R Y++ + VPC+LI ++ + F + + G
Sbjct: 231 CCDYDFVDVKIAITLQRRALYYVFNLIVPCLLISGMALMVFMLPPDAG 278
>UniRef50_O17848 Cluster: Putative uncharacterized protein acr-18;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein acr-18 - Caenorhabditis elegans
Length = 510
Score = 56.0 bits (129), Expect = 2e-06
Identities = 44/231 (19%), Positives = 93/231 (40%), Gaps = 5/231 (2%)
Query: 148 SVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRL 207
++ E+L +Y P + V+ ++ + V E D ++ C+ YW D L
Sbjct: 32 NLYEHLFLDYVKEIRPVRNESESLKVEIKFWLKQILKVDERDQIVNIYCWLELYWIDETL 91
Query: 208 SF-LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLT 266
++ +LS +IW+PD YN + V + + + G ++ +
Sbjct: 92 TWDPKKFGNLSRIHVPAHKIWKPDVLVYNNANMNVEENEMETNAI-VDNTGRVMLFRSMI 150
Query: 267 IKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFP 326
C + L+ FP D+Q C + S++ +L ++ N + +++ L F
Sbjct: 151 TDISCNLNLQQFPFDQQICFVTFASWSMDGSKLDLS-ATPKTDNLELYIRNTEWGLTDFR 209
Query: 327 YRNF--TFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFW 375
+ + + F + L+R Y++ + +P I V++ V F+
Sbjct: 210 VKIYQKIYDCCPHPFPDVTYFMVLRRSPSYYIFSLVIPSAFITVVTIVGFF 260
>UniRef50_P45963 Cluster: Acetylcholine receptor subunit alpha-type
acr-7 precursor; n=2; Caenorhabditis|Rep: Acetylcholine
receptor subunit alpha-type acr-7 precursor -
Caenorhabditis elegans
Length = 538
Score = 56.0 bits (129), Expect = 2e-06
Identities = 54/243 (22%), Positives = 96/243 (39%), Gaps = 12/243 (4%)
Query: 143 SKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYW 202
SK + +LL NY P V + I+ + V ++ + + W
Sbjct: 28 SKKEAQLYRDLLTNYSYLVRPVRNPKKALTVTMKVFIQQVLLVDAKHQMIEVNAWLKYIW 87
Query: 203 RDTRLSF--LGPIRSLSLSIKMLERIWRPDTYFYNG---KHSYVHTITVPNKLLRISQHG 257
D RL + L S+ + ++IW+PD YN IT + S G
Sbjct: 88 TDFRLRWNPLDYENITSVRFQGEDQIWQPDILLYNRYIEDEQESFDITYKTNAVAYSD-G 146
Query: 258 DILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQ----NSQSVNFVP 313
I + K C M++ FP D Q C + GS+ Y L + S +
Sbjct: 147 VINWIPPGIFKLSCKMDITLFPFDEQICFMKFGSWTYHGFALDLRLDVVKGQEPSADLST 206
Query: 314 GMTLSQFDLISFPYRNFT--FTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSW 371
+T ++ L+S P R + + + ++ +L+R T Y++ V +P +L+ +S
Sbjct: 207 YITNGEWHLLSAPARREEKFYKCCKEPYPTVKFYLHLRRRTFYYVFNVVLPTLLVSFMSL 266
Query: 372 VSF 374
++F
Sbjct: 267 LAF 269
>UniRef50_P02708 Cluster: Acetylcholine receptor subunit alpha
precursor; n=142; Coelomata|Rep: Acetylcholine receptor
subunit alpha precursor - Homo sapiens (Human)
Length = 482
Score = 56.0 bits (129), Expect = 2e-06
Identities = 36/160 (22%), Positives = 71/160 (44%), Gaps = 4/160 (2%)
Query: 224 ERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQ 283
E+IWRPD YN + LL+ + H I ++ K+ C + + +FP D Q
Sbjct: 128 EKIWRPDLVLYNNADGDFAIVKFTKVLLQYTGH--ITWTPPAIFKSYCEIIVTHFPFDEQ 185
Query: 284 SCPLILGSYAYSNQQLVYQWQNSQS--VNFVPGMTLSQFDLISFPYRNFTFTRREGDFSV 341
+C + LG++ Y + ++ Q NF+ + + + + +
Sbjct: 186 NCSMKLGTWTYDGSVVAINPESDQPDLSNFMESGEWVIKESRGWKHSVTYSCCPDTPYLD 245
Query: 342 LQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ F ++R YF++ V +PC+L L+ + F++ + G
Sbjct: 246 ITYHFVMQRLPLYFIVNVIIPCLLFSFLTGLVFYLPTDSG 285
>UniRef50_Q4SXG5 Cluster: Chromosome undetermined SCAF12416, whole
genome shotgun sequence; n=3; Tetraodontidae|Rep:
Chromosome undetermined SCAF12416, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 643
Score = 55.2 bits (127), Expect = 4e-06
Identities = 43/241 (17%), Positives = 100/241 (41%), Gaps = 9/241 (3%)
Query: 147 TSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTR 206
+++L+NL NY P VV+ +++ S ++ + + S W D R
Sbjct: 25 SALLKNLFSNYTLKVRPAVSPEQRVVVRVGMILSSFVGLNMKNEEMSTIVVMNLEWTDYR 84
Query: 207 LSFLGPIRSLSLSIKMLE--RIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
LS+ P + + + +IW PD N + +++ +G + ++
Sbjct: 85 LSW-SPKDYDGIEVLRIPSGKIWLPDIVLINNNDGVFEVALQVH--VQVYSNGRVTWTPP 141
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLIS 324
+ C +++ FP D Q+C + SY Y + ++ Q+ + + L +
Sbjct: 142 ALYCSSCGVKVEYFPFDWQNCSMQFRSYTYDSTEIDIQYALDSKGREIKEIQLDEAYTEG 201
Query: 325 ----FPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREV 380
+R + ++ + ++R Y+++ + +PCILI +++ +F++ +
Sbjct: 202 GEWYIKHRPSRKVMLDDEYEGMVFYLIIERKPLYYVLNIILPCILITIIAIFNFYLPPDA 261
Query: 381 G 381
G
Sbjct: 262 G 262
>UniRef50_Q9GUF0 Cluster: Ligand-gated ion channel protein 10; n=3;
Caenorhabditis|Rep: Ligand-gated ion channel protein 10
- Caenorhabditis elegans
Length = 493
Score = 55.2 bits (127), Expect = 4e-06
Identities = 56/229 (24%), Positives = 101/229 (44%), Gaps = 14/229 (6%)
Query: 147 TSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYF---RQYWR 203
+++L ++ Y+ LP +G P +V I++ G + EL + + Y Q W
Sbjct: 71 SAILNDIFVGYDRRVLP-FVQG-PVLVNMTIVL---GILIELKENQQLAAYVISHTQRWY 125
Query: 204 DTRLSF-LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYS 262
D RLS+ R I +W P + YN S +T +R+ +G I +
Sbjct: 126 DGRLSWDPSKYRGQREVIVPQTMVWIPKLFVYNSLESK-DMLTENRADVRLYHNGRIKIN 184
Query: 263 MRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDL 322
+ ++A C ++ +FP D Q C + L S + ++V ++ G +++ L
Sbjct: 185 IPQYVQAICRIQTESFPFDCQFCAVALASPLLNVNEMVVNATQPPRDSYFSGN--AEWYL 242
Query: 323 ISFPYRNFTFTRREGDFSV-LQVSFNLKRHTGYFLIQVYVPCILIVVLS 370
+ R+ TF EG+ V + F+L+R Y++ + P LI LS
Sbjct: 243 FNVTVRHMTF-EEEGESRVEIHYVFHLQRRPIYYITVIVAPTFLISALS 290
>UniRef50_A7RTX5 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 386
Score = 55.2 bits (127), Expect = 4e-06
Identities = 39/205 (19%), Positives = 84/205 (40%), Gaps = 6/205 (2%)
Query: 170 PTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRP 229
P VV + + + V + +++ + Q W L + R+++ + +E +W P
Sbjct: 54 PLVVTFGMTLDKLMAVDSRNQVITVNAWILQTWTHPVLKWSPRRRNVTKTRFSIEEVWVP 113
Query: 230 DTYFYNGKHSYV--HTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPL 287
DT +N V + + ++ G + T+ KC + + +PMD C L
Sbjct: 114 DTALFNNGEKAVAGRQKFFESSDVIMTYDGKAKWRTYATLTNKCKLNAKFWPMDEHVCTL 173
Query: 288 ILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFN 347
S Y+ ++ Q + ++ S++D+I + T DFS + S +
Sbjct: 174 TFSSRRYTASEMKIQSDTTNEHATTDHLSNSEWDVIKITVK----TGNVDDFSAISYSIH 229
Query: 348 LKRHTGYFLIQVYVPCILIVVLSWV 372
++R L+ + P ++ ++ V
Sbjct: 230 IRRKPQLLLLMFFTPSAILFIMGLV 254
>UniRef50_Q9GQU9 Cluster: Nicotinic acetylcholine receptor-like
subunit ACR-12; n=2; Caenorhabditis|Rep: Nicotinic
acetylcholine receptor-like subunit ACR-12 -
Caenorhabditis elegans
Length = 573
Score = 54.8 bits (126), Expect = 5e-06
Identities = 58/260 (22%), Positives = 112/260 (43%), Gaps = 31/260 (11%)
Query: 143 SKNITSVL-ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQY 201
+K++ S L E+LL +Y P V + + V E + + + +
Sbjct: 34 AKDLESQLYEDLLFDYNKVPRPVKNSSDILTVDVGASLIRIIDVDEKNQVLTTNLWLEMK 93
Query: 202 WRDTRLSFL----GPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHG 257
W D +L++ G +++L + IW PD YN IT+ L ++ G
Sbjct: 94 WNDAKLTWTPEKYGGLKTLHIPSDF---IWTPDLVLYNNAAGDPD-ITILTDAL-VTFEG 148
Query: 258 DILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYS----------NQQLVYQWQNSQ 307
++ + K+ CP+++ FP D Q C + G++ Y+ +++V ++
Sbjct: 149 NVYWQPPAIYKSFCPIDVTWFPYDSQKCEMKFGTWTYTGRYVDLKQLPQEEVVTITKDDN 208
Query: 308 SVNFV-PGMTLS------QFDLISFPYRNFT--FTRREGDFSVLQVS--FNLKRHTGYFL 356
V F+ GM LS ++DL+S + + G + ++ F L+R T +F
Sbjct: 209 DVEFMQQGMDLSFFYRSAEWDLLSLTSERHSVLYASCCGPEKYVDITYYFGLRRKTLFFT 268
Query: 357 IQVYVPCILIVVLSWVSFWI 376
+ +PC LI +L+ F++
Sbjct: 269 CNLILPCFLISILTTFVFYL 288
>UniRef50_A5H038 Cluster: Nicotinic acetylcholine receptor subunit 6
isoform VIII; n=1; Musca domestica|Rep: Nicotinic
acetylcholine receptor subunit 6 isoform VIII - Musca
domestica (House fly)
Length = 396
Score = 54.4 bits (125), Expect = 7e-06
Identities = 53/234 (22%), Positives = 90/234 (38%), Gaps = 13/234 (5%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRL- 207
+L +LL Y + P + P V+ + ++ + V E + + + W D L
Sbjct: 29 LLNHLLSTYNTLERPVANESDPLEVKFGLTLQQIIDVDEKNQLLITNLWLSLEWNDYNLR 88
Query: 208 ---SFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
S G ++ L ++ ++W+PD YN N + + +G+ LY
Sbjct: 89 WNDSEYGGVKDLRITPN---KLWKPDVLMYNSADEGFDGTYHTN--IVVKHNGNCLYVPP 143
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLIS 324
K+ C +++ FP D Q C + GS+ Y QL + + +T ++ LI
Sbjct: 144 GIFKSTCKIDITWFPFDDQHCEMKFGSWTYDGNQLDLVLSSEDGGDLSDFITNGEWYLIG 203
Query: 325 FPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHR 378
+ F SV+ L H I P I V L W+ WI R
Sbjct: 204 TYFNCIMFMVAS---SVVLTVVVLNYHHRTADIHEMPPWIRSVFLQWLP-WILR 253
>UniRef50_O95264 Cluster: 5-hydroxytryptamine 3B receptor precursor;
n=13; Theria|Rep: 5-hydroxytryptamine 3B receptor
precursor - Homo sapiens (Human)
Length = 441
Score = 54.0 bits (124), Expect = 1e-05
Identities = 47/234 (20%), Positives = 100/234 (42%), Gaps = 15/234 (6%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF- 209
+ LL+ Y P + T V ++ + ++ V + ++++ W D LS+
Sbjct: 37 KQLLQKYHKEVRPVYNWTKATTVYLDLFVHAILDVDAENQILKTSVWYQEVWNDEFLSWN 96
Query: 210 ---LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPN-KLLRISQHGDILYSMRL 265
IR +SL L IW PD + +V P+ + ++ G I +
Sbjct: 97 SSMFDEIREISLP---LSAIWAPDIII----NEFVDIERYPDLPYVYVNSSGTIENYKPI 149
Query: 266 TIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNS-QSVNFVPGMTL--SQFDL 322
+ + C +E FP D Q+C L S ++ + + + S + + L S+++L
Sbjct: 150 QVVSACSLETYAFPFDVQNCSLTFKSILHTVEDVDLAFLRSPEDIQHDKKAFLNDSEWEL 209
Query: 323 ISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
+S G F+ +Q + ++RH +++ + +P I ++++ SF++
Sbjct: 210 LSVSSTYSILQSSAGGFAQIQFNVVMRRHPLVYVVSLLIPSIFLMLVDLGSFYL 263
>UniRef50_UPI0000E4930A Cluster: PREDICTED: similar to nicotinic
acetylcholine receptor subunit Dalpha7; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
nicotinic acetylcholine receptor subunit Dalpha7 -
Strongylocentrotus purpuratus
Length = 1094
Score = 53.6 bits (123), Expect = 1e-05
Identities = 45/197 (22%), Positives = 83/197 (42%), Gaps = 7/197 (3%)
Query: 190 MDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKML-ERIWRPDTYFYNGKHSYVHTITVPN 248
+ + + RQ W D L++ I++L + IWRPD YN T
Sbjct: 749 LSFLTSSWMRQRWTDPTLAWNKSEYGGLDKIRVLPDMIWRPDILVYNSAAPKFDP-TFHT 807
Query: 249 KLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQ- 307
K+ ++ G + K CP+++ FP D Q C + GS+ Y + + + +
Sbjct: 808 KVT-VTSEGLCEWIPPGIFKTSCPIDVTYFPFDIQECEIKFGSWTYGGFTVDLELLSDEV 866
Query: 308 SVNFVPGMTLS-QFDLISFPYRN--FTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCI 364
++N + +++LI P +T + L ++R Y+ + + VPC+
Sbjct: 867 AMNDTSEFVKNGEWNLIGMPAEKKIKNYTCCPETYPSLHFYITIRRRALYYTLNILVPCL 926
Query: 365 LIVVLSWVSFWIHREVG 381
+I L+ V F + E G
Sbjct: 927 VISSLALVGFTLPVESG 943
>UniRef50_UPI0000ECB6ED Cluster: Acetylcholine receptor subunit
alpha precursor.; n=1; Gallus gallus|Rep: Acetylcholine
receptor subunit alpha precursor. - Gallus gallus
Length = 352
Score = 53.6 bits (123), Expect = 1e-05
Identities = 52/243 (21%), Positives = 102/243 (41%), Gaps = 21/243 (8%)
Query: 147 TSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTR 206
T ++++L ++Y P VV + + + V E++ + + +Q W D
Sbjct: 24 TRLVDDLFRDYSKVVRPVENHRDAVVVTVGLQLIQLINVDEVNQIVTTNVRLKQQWTDIN 83
Query: 207 LSF----LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYS 262
L + G ++ + + + IWRPD YN + LL + G I ++
Sbjct: 84 LKWNPDDYGGVKQIRIPS---DDIWRPDLVLYNNADGDFAIVKYTKVLLEHT--GKITWT 138
Query: 263 MRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQ-WQNSQSVNFVPG-MTLSQF 320
K+ C + + FP D+Q+C + LG++ Y +V N+++V P
Sbjct: 139 PPAIFKSYCEIIVTYFPFDQQNCSMKLGTWTYDGTMVVINPVSNARAVLRQPAPRGYRAI 198
Query: 321 DLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYV----PCILIVVLSWVSFWI 376
+ + P+++ R + ++ L HT Y + Y+ P +++V+L SF I
Sbjct: 199 NQVHAPHQSNPTIHR------VLLAKKLSTHTTYTSVHSYLMISTPVLVLVLLVLSSFCI 252
Query: 377 HRE 379
E
Sbjct: 253 AGE 255
>UniRef50_Q9XTE5 Cluster: Putative uncharacterized protein lgc-31;
n=3; Caenorhabditis|Rep: Putative uncharacterized
protein lgc-31 - Caenorhabditis elegans
Length = 503
Score = 53.6 bits (123), Expect = 1e-05
Identities = 33/155 (21%), Positives = 75/155 (48%), Gaps = 7/155 (4%)
Query: 226 IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSC 285
IW P+ Y + N +R++ G + Y + + ++ C ++++ FP D Q C
Sbjct: 37 IWIPEFSLYYSLNFNDAVKLQSNNDVRVNYTGQVRYYIPFSSESLCKLDVKFFPFDVQQC 96
Query: 286 PLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDL----ISFPYRNFTFTRREGD--F 339
L+ GS+A+SN + Y SQ+++ + +++L S F + + +
Sbjct: 97 SLLFGSWAHSNDSIKYSLY-SQNLSLIDFYDNQEWELDTHNSSVHSDGFLYDYLDPPLFW 155
Query: 340 SVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSF 374
++ ++ +KR + Y++ + +P +I ++S + F
Sbjct: 156 EMIIITLVMKRQSFYYVFNLVIPSTMITLVSVIGF 190
>UniRef50_UPI0000E47C59 Cluster: PREDICTED: similar to alpha-9
nicotinic acetylcholine receptor subunit precursor; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
alpha-9 nicotinic acetylcholine receptor subunit
precursor - Strongylocentrotus purpuratus
Length = 451
Score = 53.2 bits (122), Expect = 2e-05
Identities = 36/186 (19%), Positives = 81/186 (43%), Gaps = 7/186 (3%)
Query: 200 QYWRDTRLSFLGPIRSLSLSIKML-ERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGD 258
Q W+D + + + +K+ E +W PD YN + ++++ I+ G
Sbjct: 41 QNWKDEFMMWDPAVYGNITDLKIASELVWMPDVVLYNNAAKEYKDF-MKDEIVVITNEGQ 99
Query: 259 ILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLS 318
+ ++ I + C + + FP D Q CP+ G + + ++L W V
Sbjct: 100 VNWAAPKIISSYCSINVNTFPFDEQQCPMKFGPWQHEGKELRI-WGGGSGDASVFNSD-G 157
Query: 319 QFDLISFPYRN--FTFTRREG-DFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFW 375
Q+D+++ ++ + G ++ + KR Y++ + +PC + +++ +SF+
Sbjct: 158 QWDILAMTAKSNEVEYPDAPGKTYTDVTYVIKFKRRPLYYVFNLILPCTFVSMVALLSFF 217
Query: 376 IHREVG 381
+ E G
Sbjct: 218 LPPESG 223
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.319 0.133 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 585,634,920
Number of Sequences: 1657284
Number of extensions: 23328915
Number of successful extensions: 63139
Number of sequences better than 10.0: 359
Number of HSP's better than 10.0 without gapping: 240
Number of HSP's successfully gapped in prelim test: 119
Number of HSP's that attempted gapping in prelim test: 62332
Number of HSP's gapped (non-prelim): 516
length of query: 539
length of database: 575,637,011
effective HSP length: 104
effective length of query: 435
effective length of database: 403,279,475
effective search space: 175426571625
effective search space used: 175426571625
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 75 (34.3 bits)
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