Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000891-TA|BGIBMGA000891-PA|IPR006201|Neurotransmitter-
gated ion-channel, IPR006028|Gamma-aminobutyric acid A receptor,
IPR001390|Gamma-aminobutyric-acid A receptor, alpha subunit,
IPR006202|Neurotransmitter-gated ion-channel ligand-binding,
IPR006029|Neurotransmitter-gated ion-channel transmembrane region
(539 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 249 2e-65
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 249 2e-65
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 249 2e-65
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 249 2e-65
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 249 2e-65
S62907-1|AAB27278.1| 451|Homo sapiens gamma-aminobutyric acidA ... 244 5e-64
AB209295-1|BAD92532.1| 461|Homo sapiens gamma-aminobutyric acid... 244 5e-64
BC022488-1|AAH22488.1| 367|Homo sapiens GABRA2 protein protein. 244 6e-64
L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine recep... 241 3e-63
BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid... 241 3e-63
BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid... 241 3e-63
BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid... 241 3e-63
BC030696-1|AAH30696.1| 456|Homo sapiens GABRA1 protein protein. 241 6e-63
AK223447-1|BAD97167.1| 456|Homo sapiens gamma-aminobutyric acid... 241 6e-63
U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit al... 238 4e-62
BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid... 238 4e-62
X14766-1|CAA32874.1| 456|Homo sapiens GABA-A receptor alpha 1 s... 235 3e-61
AC093745-1|AAY40994.1| 222|Homo sapiens unknown protein. 234 5e-61
S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA ... 234 7e-61
AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit a... 234 7e-61
BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid... 231 5e-60
X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2 s... 229 2e-59
BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid... 227 8e-59
BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid... 227 8e-59
BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid... 227 8e-59
AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid... 227 8e-59
S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3 su... 223 9e-58
AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3 ... 223 9e-58
AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3 ... 223 9e-58
BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid... 215 4e-55
X13584-1|CAA31925.1| 354|Homo sapiens protein ( Human mRNA for ... 210 9e-54
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 207 7e-53
M82919-1|AAA52511.1| 473|Homo sapiens GABA-alpha receptor beta-... 207 9e-53
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 206 2e-52
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 206 2e-52
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 206 2e-52
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 206 2e-52
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 206 2e-52
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 206 2e-52
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 206 2e-52
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 206 2e-52
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 205 3e-52
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 205 3e-52
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 205 3e-52
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 204 5e-52
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 204 5e-52
BC010641-1|AAH10641.1| 473|Homo sapiens gamma-aminobutyric acid... 204 6e-52
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 203 1e-51
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 203 1e-51
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 203 1e-51
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 203 1e-51
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 203 1e-51
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 203 1e-51
U66661-1|AAB49284.1| 506|Homo sapiens GABA-A receptor epsilon s... 198 4e-50
BC059376-1|AAH59376.1| 365|Homo sapiens GABRE protein protein. 198 4e-50
BC047108-1|AAH47108.1| 365|Homo sapiens GABRE protein protein. 198 4e-50
BC026337-1|AAH26337.1| 365|Homo sapiens GABRE protein protein. 198 4e-50
Y09765-1|CAA70904.1| 506|Homo sapiens GABA receptor epsilon sub... 198 5e-50
U92283-1|AAB94645.1| 506|Homo sapiens GABA-A receptor epsilon s... 198 5e-50
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 196 2e-49
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 196 2e-49
Y09763-1|CAA70903.1| 506|Homo sapiens GABRE protein. 195 3e-49
Y07637-1|CAA68914.1| 505|Homo sapiens putative GABA-gated chlor... 195 4e-49
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 192 3e-48
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 192 3e-48
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 191 6e-48
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 188 6e-47
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 182 4e-45
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 182 4e-45
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 182 4e-45
M86868-1|AAA52510.1| 465|Homo sapiens gamma-amino butyric acid ... 179 3e-44
BC130354-1|AAI30355.1| 465|Homo sapiens gamma-aminobutyric acid... 178 3e-44
BC130352-1|AAI30353.1| 465|Homo sapiens gamma-aminobutyric acid... 178 3e-44
AL121833-2|CAC07339.1| 465|Homo sapiens gamma-aminobutyric acid... 178 3e-44
M62400-1|AAA52509.1| 473|Homo sapiens gamma-aminobutyric acid r... 176 2e-43
BC130344-1|AAI30345.1| 474|Homo sapiens gamma-aminobutyric acid... 176 2e-43
AL353659-1|CAC36328.2| 473|Homo sapiens gamma-aminobutyric acid... 176 2e-43
AL353135-4|CAI16246.1| 473|Homo sapiens gamma-aminobutyric acid... 176 2e-43
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 175 3e-43
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 175 3e-43
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 175 3e-43
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 175 3e-43
U33267-1|AAB37750.1| 497|Homo sapiens glycine receptor beta sub... 173 2e-42
BC032635-1|AAH32635.1| 497|Homo sapiens glycine receptor, beta ... 173 2e-42
AF094755-1|AAC71034.1| 497|Homo sapiens glycine receptor beta s... 173 2e-42
AF094754-1|AAC71033.1| 497|Homo sapiens glycine receptor beta s... 173 2e-42
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 169 2e-41
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 169 2e-41
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 169 2e-41
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 169 2e-41
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 169 2e-41
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 169 2e-41
AF228447-1|AAF62508.1| 96|Homo sapiens gamma-aminobutyric acid... 113 1e-24
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 81 1e-14
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 80 2e-14
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 80 2e-14
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 80 2e-14
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 80 2e-14
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 80 2e-14
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 80 2e-14
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 78 7e-14
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 73 2e-12
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 73 2e-12
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 73 2e-12
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 73 2e-12
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 73 2e-12
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 73 3e-12
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 73 3e-12
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 73 3e-12
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 73 3e-12
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 73 3e-12
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 73 3e-12
AC131948-1|AAY40916.1| 74|Homo sapiens unknown protein. 72 6e-12
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 71 1e-11
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 71 1e-11
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 71 1e-11
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 71 1e-11
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 71 1e-11
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 70 2e-11
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 70 2e-11
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 70 2e-11
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 70 2e-11
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 70 2e-11
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 70 2e-11
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 70 2e-11
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 70 2e-11
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 69 3e-11
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 69 3e-11
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 69 6e-11
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 68 7e-11
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 68 7e-11
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 68 7e-11
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 68 7e-11
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 68 7e-11
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 68 7e-11
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 68 7e-11
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 68 7e-11
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 68 7e-11
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 68 7e-11
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 68 7e-11
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 68 7e-11
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 68 7e-11
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 68 1e-10
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 66 2e-10
D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor ... 66 4e-10
BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine (se... 66 4e-10
BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine (se... 66 4e-10
BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine (se... 66 4e-10
AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor pr... 66 4e-10
AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3 re... 66 4e-10
AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor prot... 66 4e-10
AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine rec... 66 4e-10
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 64 1e-09
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 64 1e-09
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 64 1e-09
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 64 1e-09
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 64 1e-09
S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type ... 64 2e-09
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 63 2e-09
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 63 2e-09
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 63 2e-09
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 63 2e-09
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 63 2e-09
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 63 2e-09
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 61 8e-09
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 61 8e-09
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 61 8e-09
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 61 8e-09
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 61 8e-09
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 61 8e-09
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 61 8e-09
AL121827-20|CAC36119.1| 627|Homo sapiens cholinergic receptor, ... 61 8e-09
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 61 1e-08
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 61 1e-08
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 59 3e-08
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 59 3e-08
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 59 3e-08
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 59 3e-08
AF018157-1|AAC39918.1| 219|Homo sapiens glycine receptor alpha ... 58 1e-07
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 57 1e-07
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 57 1e-07
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 57 1e-07
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 57 1e-07
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 57 2e-07
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 55 5e-07
BC101348-1|AAI01349.1| 412|Homo sapiens CHRNA7 (cholinergic rec... 54 1e-06
BC101347-1|AAI01348.1| 412|Homo sapiens CHRNA7 (cholinergic rec... 54 1e-06
BC101346-1|AAI01347.1| 412|Homo sapiens CHRNA7 (cholinergic rec... 54 1e-06
AF169255-1|AAF03691.1| 441|Homo sapiens 5-hydroxytryptamine 3 r... 54 1e-06
AF080582-1|AAD12242.1| 441|Homo sapiens 5-hydroxytryptamine 3 r... 54 1e-06
AM293589-1|CAL25321.1| 430|Homo sapiens 5-hydroxytryptamine rec... 54 2e-06
AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor prot... 52 4e-06
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 48 8e-05
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 48 8e-05
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 46 3e-04
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 46 3e-04
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 46 3e-04
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 46 3e-04
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 46 4e-04
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 46 4e-04
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 44 0.001
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 44 0.001
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 44 0.001
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 44 0.001
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 44 0.002
AF053072-1|AAD19830.1| 74|Homo sapiens GABA subunit A receptor... 44 0.002
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 43 0.002
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 42 0.005
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 42 0.005
BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein. 42 0.005
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 42 0.005
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 42 0.005
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 42 0.005
AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor, n... 42 0.005
Y18994-1|CAB60835.1| 99|Homo sapiens GABA-C receptor rho3 subu... 41 0.010
AK127001-1|BAC86784.1| 133|Homo sapiens protein ( Homo sapiens ... 36 0.27
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 35 0.63
BC050330-1|AAH50330.1| 1459|Homo sapiens ALMS1 protein protein. 31 7.7
BC035025-1|AAH35025.1| 1459|Homo sapiens ALMS1 protein protein. 31 7.7
AJ417593-1|CAD10391.2| 4169|Homo sapiens ALMS1 protein protein. 31 7.7
AC096546-1|AAX82023.1| 1291|Homo sapiens unknown protein. 31 7.7
AB002326-1|BAA20786.3| 2055|Homo sapiens KIAA0328 protein protein. 31 7.7
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 249 bits (609), Expect = 2e-65
Identities = 117/240 (48%), Positives = 161/240 (67%), Gaps = 4/240 (1%)
Query: 143 SKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYW 202
S+N++ +L+NLL+ Y+N P G G T V+T+I + S GPVS+++M+Y+MD +FRQ W
Sbjct: 29 SENVSRILDNLLEGYDNRLRPGFG-GAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTW 87
Query: 203 RDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYS 262
D RL F GP LSL+ M+ +IW PDT+F NGK S H +T PNKL RI Q+G ILY+
Sbjct: 88 TDERLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYT 147
Query: 263 MRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNF-VP--GMTLSQ 319
MRLTI A CPM L NFPMD +CPL GSYAY +++Y W+ + VP +L Q
Sbjct: 148 MRLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQ 207
Query: 320 FDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
+DLI + T G++ ++ V F+L+R GYF+IQ+Y PCI+ V+LS VSFWI++E
Sbjct: 208 YDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKE 267
Score = 37.5 bits (83), Expect = 0.12
Identities = 14/26 (53%), Positives = 20/26 (76%)
Query: 495 SHIDRAARVLFPASFALLNLFYWMIY 520
S ID+ +R+LFP +FA NL YW++Y
Sbjct: 415 SKIDQYSRILFPVAFAGFNLVYWVVY 440
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 249 bits (609), Expect = 2e-65
Identities = 117/240 (48%), Positives = 161/240 (67%), Gaps = 4/240 (1%)
Query: 143 SKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYW 202
S+N++ +L+NLL+ Y+N P G G T V+T+I + S GPVS+++M+Y+MD +FRQ W
Sbjct: 29 SENVSRILDNLLEGYDNRLRPGFG-GAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTW 87
Query: 203 RDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYS 262
D RL F GP LSL+ M+ +IW PDT+F NGK S H +T PNKL RI Q+G ILY+
Sbjct: 88 TDERLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYT 147
Query: 263 MRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNF-VP--GMTLSQ 319
MRLTI A CPM L NFPMD +CPL GSYAY +++Y W+ + VP +L Q
Sbjct: 148 MRLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQ 207
Query: 320 FDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
+DLI + T G++ ++ V F+L+R GYF+IQ+Y PCI+ V+LS VSFWI++E
Sbjct: 208 YDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKE 267
Score = 37.5 bits (83), Expect = 0.12
Identities = 14/26 (53%), Positives = 20/26 (76%)
Query: 495 SHIDRAARVLFPASFALLNLFYWMIY 520
S ID+ +R+LFP +FA NL YW++Y
Sbjct: 415 SKIDQYSRILFPVAFAGFNLVYWVVY 440
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 249 bits (609), Expect = 2e-65
Identities = 117/240 (48%), Positives = 161/240 (67%), Gaps = 4/240 (1%)
Query: 143 SKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYW 202
S+N++ +L+NLL+ Y+N P G G T V+T+I + S GPVS+++M+Y+MD +FRQ W
Sbjct: 29 SENVSRILDNLLEGYDNRLRPGFG-GAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTW 87
Query: 203 RDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYS 262
D RL F GP LSL+ M+ +IW PDT+F NGK S H +T PNKL RI Q+G ILY+
Sbjct: 88 TDERLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYT 147
Query: 263 MRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNF-VP--GMTLSQ 319
MRLTI A CPM L NFPMD +CPL GSYAY +++Y W+ + VP +L Q
Sbjct: 148 MRLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQ 207
Query: 320 FDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
+DLI + T G++ ++ V F+L+R GYF+IQ+Y PCI+ V+LS VSFWI++E
Sbjct: 208 YDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKE 267
Score = 37.5 bits (83), Expect = 0.12
Identities = 14/26 (53%), Positives = 20/26 (76%)
Query: 495 SHIDRAARVLFPASFALLNLFYWMIY 520
S ID+ +R+LFP +FA NL YW++Y
Sbjct: 415 SKIDQYSRILFPVAFAGFNLVYWVVY 440
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 249 bits (609), Expect = 2e-65
Identities = 117/240 (48%), Positives = 161/240 (67%), Gaps = 4/240 (1%)
Query: 143 SKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYW 202
S+N++ +L+NLL+ Y+N P G G T V+T+I + S GPVS+++M+Y+MD +FRQ W
Sbjct: 29 SENVSRILDNLLEGYDNRLRPGFG-GAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTW 87
Query: 203 RDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYS 262
D RL F GP LSL+ M+ +IW PDT+F NGK S H +T PNKL RI Q+G ILY+
Sbjct: 88 TDERLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYT 147
Query: 263 MRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNF-VP--GMTLSQ 319
MRLTI A CPM L NFPMD +CPL GSYAY +++Y W+ + VP +L Q
Sbjct: 148 MRLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQ 207
Query: 320 FDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
+DLI + T G++ ++ V F+L+R GYF+IQ+Y PCI+ V+LS VSFWI++E
Sbjct: 208 YDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKE 267
Score = 37.5 bits (83), Expect = 0.12
Identities = 14/26 (53%), Positives = 20/26 (76%)
Query: 495 SHIDRAARVLFPASFALLNLFYWMIY 520
S ID+ +R+LFP +FA NL YW++Y
Sbjct: 415 SKIDQYSRILFPVAFAGFNLVYWVVY 440
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 249 bits (609), Expect = 2e-65
Identities = 117/240 (48%), Positives = 161/240 (67%), Gaps = 4/240 (1%)
Query: 143 SKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYW 202
S+N++ +L+NLL+ Y+N P G G T V+T+I + S GPVS+++M+Y+MD +FRQ W
Sbjct: 29 SENVSRILDNLLEGYDNRLRPGFG-GAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTW 87
Query: 203 RDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYS 262
D RL F GP LSL+ M+ +IW PDT+F NGK S H +T PNKL RI Q+G ILY+
Sbjct: 88 TDERLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYT 147
Query: 263 MRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNF-VP--GMTLSQ 319
MRLTI A CPM L NFPMD +CPL GSYAY +++Y W+ + VP +L Q
Sbjct: 148 MRLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQ 207
Query: 320 FDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
+DLI + T G++ ++ V F+L+R GYF+IQ+Y PCI+ V+LS VSFWI++E
Sbjct: 208 YDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKE 267
Score = 37.5 bits (83), Expect = 0.12
Identities = 14/26 (53%), Positives = 20/26 (76%)
Query: 495 SHIDRAARVLFPASFALLNLFYWMIY 520
S ID+ +R+LFP +FA NL YW++Y
Sbjct: 415 SKIDQYSRILFPVAFAGFNLVYWVVY 440
>S62907-1|AAB27278.1| 451|Homo sapiens gamma-aminobutyric acidA
receptor alpha 2 subunit protein.
Length = 451
Score = 244 bits (598), Expect = 5e-64
Identities = 115/236 (48%), Positives = 155/236 (65%), Gaps = 4/236 (1%)
Query: 147 TSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTR 206
T +L+ LL Y+N P G T V TNI + S GPVS+ DM+Y++D +FRQ W+D R
Sbjct: 43 TRILDRLLDGYDNRLRPGLGDSI-TEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDER 101
Query: 207 LSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLT 266
L F GP+ L L+ M +IW PDT+F+NGK S H +T+PNKLLRI G +LY+MRLT
Sbjct: 102 LKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLT 161
Query: 267 IKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW--QNSQSVNFVP-GMTLSQFDLI 323
++A+CPM L +FPMD SCPL GSYAY+ ++ Y W S SV P G L+Q+DL+
Sbjct: 162 VQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLL 221
Query: 324 SFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
T G+++V+ F+LKR GYF+IQ Y+PCI+ V+LS VSFW++RE
Sbjct: 222 GQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 277
Score = 41.9 bits (94), Expect = 0.005
Identities = 17/43 (39%), Positives = 25/43 (58%)
Query: 478 RRQRQREAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
++ + A ++ NSVS IDR +R++FP F NL YW Y
Sbjct: 398 KKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATY 440
>AB209295-1|BAD92532.1| 461|Homo sapiens gamma-aminobutyric acid A
receptor, alpha 2 precursor variant protein.
Length = 461
Score = 244 bits (598), Expect = 5e-64
Identities = 115/236 (48%), Positives = 155/236 (65%), Gaps = 4/236 (1%)
Query: 147 TSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTR 206
T +L+ LL Y+N P G T V TNI + S GPVS+ DM+Y++D +FRQ W+D R
Sbjct: 53 TRILDRLLDGYDNRLRPGLGDSI-TEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDER 111
Query: 207 LSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLT 266
L F GP+ L L+ M +IW PDT+F+NGK S H +T+PNKLLRI G +LY+MRLT
Sbjct: 112 LKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLT 171
Query: 267 IKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW--QNSQSVNFVP-GMTLSQFDLI 323
++A+CPM L +FPMD SCPL GSYAY+ ++ Y W S SV P G L+Q+DL+
Sbjct: 172 VQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLL 231
Query: 324 SFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
T G+++V+ F+LKR GYF+IQ Y+PCI+ V+LS VSFW++RE
Sbjct: 232 GQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 287
Score = 41.9 bits (94), Expect = 0.005
Identities = 17/43 (39%), Positives = 25/43 (58%)
Query: 478 RRQRQREAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
++ + A ++ NSVS IDR +R++FP F NL YW Y
Sbjct: 408 KKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATY 450
>BC022488-1|AAH22488.1| 367|Homo sapiens GABRA2 protein protein.
Length = 367
Score = 244 bits (597), Expect = 6e-64
Identities = 115/236 (48%), Positives = 155/236 (65%), Gaps = 4/236 (1%)
Query: 147 TSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTR 206
T +L+ LL Y+N P G T V TNI + S GPVS+ DM+Y++D +FRQ W+D R
Sbjct: 43 TRILDRLLDGYDNRLRPGLGDSI-TEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDER 101
Query: 207 LSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLT 266
L F GP+ L L+ M +IW PDT+F+NGK S H +T+PNKLLRI G +LY+MRLT
Sbjct: 102 LKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSAAHNMTMPNKLLRIQDDGTLLYTMRLT 161
Query: 267 IKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW--QNSQSVNFVP-GMTLSQFDLI 323
++A+CPM L +FPMD SCPL GSYAY+ ++ Y W S SV P G L+Q+DL+
Sbjct: 162 VQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLL 221
Query: 324 SFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
T G+++V+ F+LKR GYF+IQ Y+PCI+ V+LS VSFW++RE
Sbjct: 222 GQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 277
>L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine receptor
alpha-5-subunit protein.
Length = 462
Score = 241 bits (591), Expect = 3e-63
Identities = 112/249 (44%), Positives = 163/249 (65%), Gaps = 7/249 (2%)
Query: 137 SINDAVSKNIT---SVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYS 193
S+ D + NIT +L+ LL Y+N P G+ T V+T+I + S GPVS+ +M+Y+
Sbjct: 37 SVKDETNDNITIFTRILDGLLDGYDNRLRPGLGERI-TQVRTDIYVTSFGPVSDTEMEYT 95
Query: 194 MDCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRI 253
+D +FRQ W+D RL F GP++ L L+ + +IW PDT+F+NGK S H +T PNKLLR+
Sbjct: 96 IDVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRL 155
Query: 254 SQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFV- 312
G +LY+MRLTI A+CPM+L +FPMD +CPL GSYAY N ++VY W N + + V
Sbjct: 156 EDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVV 215
Query: 313 --PGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLS 370
G L+Q+ L+ + G+++++ F+LKR GYF+IQ Y+PCI+ V+LS
Sbjct: 216 AEDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILS 275
Query: 371 WVSFWIHRE 379
VSFW++RE
Sbjct: 276 QVSFWLNRE 284
Score = 39.5 bits (88), Expect = 0.029
Identities = 15/39 (38%), Positives = 24/39 (61%)
Query: 482 QREAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
++ + S+ NS+S ID+ +R++FP F NL YW Y
Sbjct: 410 EKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATY 448
>BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 241 bits (591), Expect = 3e-63
Identities = 112/249 (44%), Positives = 163/249 (65%), Gaps = 7/249 (2%)
Query: 137 SINDAVSKNIT---SVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYS 193
S+ D + NIT +L+ LL Y+N P G+ T V+T+I + S GPVS+ +M+Y+
Sbjct: 37 SVKDETNDNITIFTRILDGLLDGYDNRLRPGLGERI-TQVRTDIYVTSFGPVSDTEMEYT 95
Query: 194 MDCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRI 253
+D +FRQ W+D RL F GP++ L L+ + +IW PDT+F+NGK S H +T PNKLLR+
Sbjct: 96 IDVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRL 155
Query: 254 SQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFV- 312
G +LY+MRLTI A+CPM+L +FPMD +CPL GSYAY N ++VY W N + + V
Sbjct: 156 EDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVV 215
Query: 313 --PGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLS 370
G L+Q+ L+ + G+++++ F+LKR GYF+IQ Y+PCI+ V+LS
Sbjct: 216 AEDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILS 275
Query: 371 WVSFWIHRE 379
VSFW++RE
Sbjct: 276 QVSFWLNRE 284
Score = 39.5 bits (88), Expect = 0.029
Identities = 15/39 (38%), Positives = 24/39 (61%)
Query: 482 QREAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
++ + S+ NS+S ID+ +R++FP F NL YW Y
Sbjct: 410 EKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATY 448
>BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 241 bits (591), Expect = 3e-63
Identities = 112/249 (44%), Positives = 163/249 (65%), Gaps = 7/249 (2%)
Query: 137 SINDAVSKNIT---SVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYS 193
S+ D + NIT +L+ LL Y+N P G+ T V+T+I + S GPVS+ +M+Y+
Sbjct: 37 SVKDETNDNITIFTRILDGLLDGYDNRLRPGLGERI-TQVRTDIYVTSFGPVSDTEMEYT 95
Query: 194 MDCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRI 253
+D +FRQ W+D RL F GP++ L L+ + +IW PDT+F+NGK S H +T PNKLLR+
Sbjct: 96 IDVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRL 155
Query: 254 SQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFV- 312
G +LY+MRLTI A+CPM+L +FPMD +CPL GSYAY N ++VY W N + + V
Sbjct: 156 EDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVV 215
Query: 313 --PGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLS 370
G L+Q+ L+ + G+++++ F+LKR GYF+IQ Y+PCI+ V+LS
Sbjct: 216 AEDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILS 275
Query: 371 WVSFWIHRE 379
VSFW++RE
Sbjct: 276 QVSFWLNRE 284
Score = 39.5 bits (88), Expect = 0.029
Identities = 15/39 (38%), Positives = 24/39 (61%)
Query: 482 QREAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
++ + S+ NS+S ID+ +R++FP F NL YW Y
Sbjct: 410 EKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATY 448
>BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5, precursor protein.
Length = 462
Score = 241 bits (591), Expect = 3e-63
Identities = 112/249 (44%), Positives = 163/249 (65%), Gaps = 7/249 (2%)
Query: 137 SINDAVSKNIT---SVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYS 193
S+ D + NIT +L+ LL Y+N P G+ T V+T+I + S GPVS+ +M+Y+
Sbjct: 37 SVKDETNDNITIFTRILDGLLDGYDNRLRPGLGERI-TQVRTDIYVTSFGPVSDTEMEYT 95
Query: 194 MDCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRI 253
+D +FRQ W+D RL F GP++ L L+ + +IW PDT+F+NGK S H +T PNKLLR+
Sbjct: 96 IDVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRL 155
Query: 254 SQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFV- 312
G +LY+MRLTI A+CPM+L +FPMD +CPL GSYAY N ++VY W N + + V
Sbjct: 156 EDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVV 215
Query: 313 --PGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLS 370
G L+Q+ L+ + G+++++ F+LKR GYF+IQ Y+PCI+ V+LS
Sbjct: 216 AEDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILS 275
Query: 371 WVSFWIHRE 379
VSFW++RE
Sbjct: 276 QVSFWLNRE 284
Score = 39.5 bits (88), Expect = 0.029
Identities = 15/39 (38%), Positives = 24/39 (61%)
Query: 482 QREAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
++ + S+ NS+S ID+ +R++FP F NL YW Y
Sbjct: 410 EKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATY 448
>BC030696-1|AAH30696.1| 456|Homo sapiens GABRA1 protein protein.
Length = 456
Score = 241 bits (589), Expect = 6e-63
Identities = 113/249 (45%), Positives = 164/249 (65%), Gaps = 7/249 (2%)
Query: 137 SINDAVSKN---ITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYS 193
S+ D + N T +L+ LL Y+N P G+ T V+T+I + S GPVS+ DM+Y+
Sbjct: 30 SLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERV-TEVKTDIFVTSFGPVSDHDMEYT 88
Query: 194 MDCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRI 253
+D +FRQ W+D RL F GP+ L L+ M +IW PDT+F+NGK S H +T+PNKLLRI
Sbjct: 89 IDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRI 148
Query: 254 SQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFV- 312
++ G +LY+MRLT++A+CPM L +FPMD +CPL GSYAY+ ++VY+W + + V
Sbjct: 149 TEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVV 208
Query: 313 --PGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLS 370
G L+Q+DL+ + G++ V+ F+LKR GYF+IQ Y+PCI+ V+LS
Sbjct: 209 AEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS 268
Query: 371 WVSFWIHRE 379
VSFW++RE
Sbjct: 269 QVSFWLNRE 277
Score = 39.9 bits (89), Expect = 0.022
Identities = 16/29 (55%), Positives = 19/29 (65%)
Query: 492 NSVSHIDRAARVLFPASFALLNLFYWMIY 520
NSVS IDR +R+ FP F + NL YW Y
Sbjct: 414 NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>AK223447-1|BAD97167.1| 456|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 1 precursor variant protein.
Length = 456
Score = 241 bits (589), Expect = 6e-63
Identities = 113/249 (45%), Positives = 164/249 (65%), Gaps = 7/249 (2%)
Query: 137 SINDAVSKN---ITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYS 193
S+ D + N T +L+ LL Y+N P G+ T V+T+I + S GPVS+ DM+Y+
Sbjct: 30 SLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERV-TEVKTDIFVTSFGPVSDHDMEYT 88
Query: 194 MDCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRI 253
+D +FRQ W+D RL F GP+ L L+ M +IW PDT+F+NGK S H +T+PNKLLRI
Sbjct: 89 IDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRI 148
Query: 254 SQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFV- 312
++ G +LY+MRLT++A+CPM L +FPMD +CPL GSYAY+ ++VY+W + + V
Sbjct: 149 TEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVV 208
Query: 313 --PGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLS 370
G L+Q+DL+ + G++ V+ F+LKR GYF+IQ Y+PCI+ V+LS
Sbjct: 209 AEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS 268
Query: 371 WVSFWIHRE 379
VSFW++RE
Sbjct: 269 QVSFWLNRE 277
Score = 39.9 bits (89), Expect = 0.022
Identities = 16/29 (55%), Positives = 19/29 (65%)
Query: 492 NSVSHIDRAARVLFPASFALLNLFYWMIY 520
NSVS IDR +R+ FP F + NL YW Y
Sbjct: 414 NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit
alpha4 protein.
Length = 554
Score = 238 bits (582), Expect = 4e-62
Identities = 113/240 (47%), Positives = 159/240 (66%), Gaps = 4/240 (1%)
Query: 143 SKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYW 202
++N T +L++LL Y+N P G G T V+T+I + S GPVS+++M+Y+MD +FRQ W
Sbjct: 45 TENFTRILDSLLDGYDNRLRPGFG-GPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTW 103
Query: 203 RDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYS 262
D RL + GPI L L+ M+ ++W PDT+F NGK S H +T PNKL RI ++G ILY+
Sbjct: 104 IDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYT 163
Query: 263 MRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNF-VP--GMTLSQ 319
MRLTI A+CPM L +FPMD +CPL GSYAY +++Y W + VP +L Q
Sbjct: 164 MRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTKGPEKSVEVPKESSSLVQ 223
Query: 320 FDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
+DLI + T G++ V+ V F+L+R GYF+IQ Y+PCI+ V+LS VSFWI++E
Sbjct: 224 YDLIGQTVSSETIKSITGEYIVMTVYFHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKE 283
Score = 38.7 bits (86), Expect = 0.051
Identities = 16/41 (39%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
Query: 492 NSVSHIDRAARVLFPASFALLNLFYWMIYAFSSDDFAWSDN 532
+ S ID+ AR+LFP +F N+ YW++Y S D S++
Sbjct: 513 SGTSKIDKYARILFPVTFGAFNMVYWVVY-LSKDTMEKSES 552
>BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 4 protein.
Length = 554
Score = 238 bits (582), Expect = 4e-62
Identities = 113/240 (47%), Positives = 159/240 (66%), Gaps = 4/240 (1%)
Query: 143 SKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYW 202
++N T +L++LL Y+N P G G T V+T+I + S GPVS+++M+Y+MD +FRQ W
Sbjct: 45 TENFTRILDSLLDGYDNRLRPGFG-GPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTW 103
Query: 203 RDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYS 262
D RL + GPI L L+ M+ ++W PDT+F NGK S H +T PNKL RI ++G ILY+
Sbjct: 104 IDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYT 163
Query: 263 MRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNF-VP--GMTLSQ 319
MRLTI A+CPM L +FPMD +CPL GSYAY +++Y W + VP +L Q
Sbjct: 164 MRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTKGPEKSVEVPKESSSLVQ 223
Query: 320 FDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
+DLI + T G++ V+ V F+L+R GYF+IQ Y+PCI+ V+LS VSFWI++E
Sbjct: 224 YDLIGQTVSSETIKSITGEYIVMTVYFHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKE 283
Score = 38.7 bits (86), Expect = 0.051
Identities = 16/41 (39%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
Query: 492 NSVSHIDRAARVLFPASFALLNLFYWMIYAFSSDDFAWSDN 532
+ S ID+ AR+LFP +F N+ YW++Y S D S++
Sbjct: 513 SGTSKIDKYARILFPVTFGAFNMVYWVVY-LSKDTMEKSES 552
>X14766-1|CAA32874.1| 456|Homo sapiens GABA-A receptor alpha 1
subunit protein.
Length = 456
Score = 235 bits (575), Expect = 3e-61
Identities = 112/249 (44%), Positives = 163/249 (65%), Gaps = 7/249 (2%)
Query: 137 SINDAVSKN---ITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYS 193
S+ D + N T +L+ LL Y+N P G+ T V+T+I + S GPVS+ DM+Y+
Sbjct: 30 SLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERV-TEVKTDIFVTSFGPVSDHDMEYT 88
Query: 194 MDCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRI 253
+D +FRQ W+D RL F GP+ L L+ M +I PDT+F+NGK S H +T+PNKLLRI
Sbjct: 89 IDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIRTPDTFFHNGKKSVAHNMTMPNKLLRI 148
Query: 254 SQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFV- 312
++ G +LY+MRLT++A+CPM L +FPMD +CPL GSYAY+ ++VY+W + + V
Sbjct: 149 TEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVV 208
Query: 313 --PGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLS 370
G L+Q+DL+ + G++ V+ F+LKR GYF+IQ Y+PCI+ V+LS
Sbjct: 209 AEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS 268
Query: 371 WVSFWIHRE 379
VSFW++RE
Sbjct: 269 QVSFWLNRE 277
Score = 39.9 bits (89), Expect = 0.022
Identities = 16/29 (55%), Positives = 19/29 (65%)
Query: 492 NSVSHIDRAARVLFPASFALLNLFYWMIY 520
NSVS IDR +R+ FP F + NL YW Y
Sbjct: 414 NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>AC093745-1|AAY40994.1| 222|Homo sapiens unknown protein.
Length = 222
Score = 234 bits (573), Expect = 5e-61
Identities = 107/212 (50%), Positives = 144/212 (67%), Gaps = 3/212 (1%)
Query: 171 TVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPD 230
T V TNI + S GPVS+ DM+Y++D +FRQ W+D RL F GP+ L L+ M +IW PD
Sbjct: 3 TEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASKIWTPD 62
Query: 231 TYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILG 290
T+F+NGK S H +T+PNKLLRI G +LY+MRLT++A+CPM L +FPMD SCPL G
Sbjct: 63 TFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFG 122
Query: 291 SYAYSNQQLVYQW--QNSQSVNFVP-GMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFN 347
SYAY+ ++ Y W S SV P G L+Q+DL+ T G+++V+ F+
Sbjct: 123 SYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFH 182
Query: 348 LKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
LKR GYF+IQ Y+PCI+ V+LS VSFW++RE
Sbjct: 183 LKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 214
>S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA
receptor alpha 3 subunit protein.
Length = 492
Score = 234 bits (572), Expect = 7e-61
Identities = 110/236 (46%), Positives = 154/236 (65%), Gaps = 4/236 (1%)
Query: 147 TSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTR 206
T +L+ LL Y+N P G T V+T+I + S GPVS+ DM+Y++D +FRQ W D R
Sbjct: 68 TRILDRLLDGYDNRLRPGLGDAV-TEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDER 126
Query: 207 LSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLT 266
L F GP++ L L+ + +IW PDT+F+NGK S H +T PNKLLR+ +G +LY+MRLT
Sbjct: 127 LKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLT 186
Query: 267 IKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQ--NSQSVNFV-PGMTLSQFDLI 323
I A+CPM L +FPMD +CPL GSYAY+ ++VY W ++SV G L+Q+DL+
Sbjct: 187 IHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLL 246
Query: 324 SFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
G++ V+ F+LKR GYF+IQ Y+PCI+ V+LS VSFW++RE
Sbjct: 247 GHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 302
Score = 41.5 bits (93), Expect = 0.007
Identities = 15/29 (51%), Positives = 21/29 (72%)
Query: 492 NSVSHIDRAARVLFPASFALLNLFYWMIY 520
NSVS +D+ +R++FP FA+ NL YW Y
Sbjct: 450 NSVSKVDKISRIIFPVLFAIFNLVYWATY 478
>AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit
alpha 3 protein.
Length = 492
Score = 234 bits (572), Expect = 7e-61
Identities = 110/236 (46%), Positives = 154/236 (65%), Gaps = 4/236 (1%)
Query: 147 TSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTR 206
T +L+ LL Y+N P G T V+T+I + S GPVS+ DM+Y++D +FRQ W D R
Sbjct: 68 TRILDRLLDGYDNRLRPGLGDAV-TEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDER 126
Query: 207 LSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLT 266
L F GP++ L L+ + +IW PDT+F+NGK S H +T PNKLLR+ +G +LY+MRLT
Sbjct: 127 LKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLT 186
Query: 267 IKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQ--NSQSVNFV-PGMTLSQFDLI 323
I A+CPM L +FPMD +CPL GSYAY+ ++VY W ++SV G L+Q+DL+
Sbjct: 187 IHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLL 246
Query: 324 SFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
G++ V+ F+LKR GYF+IQ Y+PCI+ V+LS VSFW++RE
Sbjct: 247 GHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 302
Score = 41.5 bits (93), Expect = 0.007
Identities = 15/29 (51%), Positives = 21/29 (72%)
Query: 492 NSVSHIDRAARVLFPASFALLNLFYWMIY 520
NSVS +D+ +R++FP FA+ NL YW Y
Sbjct: 450 NSVSKVDKISRIIFPVLFAIFNLVYWATY 478
>BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 3 protein.
Length = 492
Score = 231 bits (565), Expect = 5e-60
Identities = 109/236 (46%), Positives = 153/236 (64%), Gaps = 4/236 (1%)
Query: 147 TSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTR 206
T +L+ LL Y+N P G T V+T+I + S GPVS+ DM+Y++D +FRQ W D R
Sbjct: 68 TRILDRLLDGYDNRLRPGLGDAV-TEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDER 126
Query: 207 LSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLT 266
L F GP++ L L+ + +IW PDT+F+NGK S H +T PNKLLR+ +G + Y+MRLT
Sbjct: 127 LKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPYTMRLT 186
Query: 267 IKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQ--NSQSVNFV-PGMTLSQFDLI 323
I A+CPM L +FPMD +CPL GSYAY+ ++VY W ++SV G L+Q+DL+
Sbjct: 187 IHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLL 246
Query: 324 SFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
G++ V+ F+LKR GYF+IQ Y+PCI+ V+LS VSFW++RE
Sbjct: 247 GHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 302
Score = 41.5 bits (93), Expect = 0.007
Identities = 15/29 (51%), Positives = 21/29 (72%)
Query: 492 NSVSHIDRAARVLFPASFALLNLFYWMIY 520
NSVS +D+ +R++FP FA+ NL YW Y
Sbjct: 450 NSVSKVDKISRIIFPVLFAIFNLVYWATY 478
>X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2
subunit protein.
Length = 467
Score = 229 bits (559), Expect = 2e-59
Identities = 105/236 (44%), Positives = 148/236 (62%), Gaps = 2/236 (0%)
Query: 145 NITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 204
++T +L NLL+ Y+N P G PT++ T++ + S+GPV+ ++M+Y++D +F Q W D
Sbjct: 65 DVTVILNNLLEGYDNKLRPDIGVK-PTLIHTDMYVNSIGPVNAINMEYTIDIFFAQMWYD 123
Query: 205 TRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
RL F I+ L L+ M+ +IW PDT+F N K + H IT PN++LRI G +LYS+R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYSLR 183
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQ-SVNFVPGMTLSQFDLI 323
LTI A+C ++L NFPMD SCPL SY Y +++VYQW+ S V L QF +
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFV 243
Query: 324 SFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
GD+ V+ V F+L R GYF IQ Y+PC LIVVLSWVSFWI+++
Sbjct: 244 GLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKD 299
Score = 36.3 bits (80), Expect = 0.27
Identities = 15/35 (42%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
Query: 488 RGHINSVSHIDRAARVLFPASFALLNLFYWMIYAF 522
R HI ++ +D AR+ FP +F L NL YW+ Y +
Sbjct: 433 RIHIR-IAKMDSYARIFFPTAFCLFNLVYWVSYLY 466
>BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 467
Score = 227 bits (555), Expect = 8e-59
Identities = 104/236 (44%), Positives = 148/236 (62%), Gaps = 2/236 (0%)
Query: 145 NITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 204
++T +L NLL+ Y+N P G PT++ T++ + S+GPV+ ++M+Y++D +F Q W D
Sbjct: 65 DVTVILNNLLEGYDNKLRPDIGVK-PTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYD 123
Query: 205 TRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
RL F I+ L L+ M+ +IW PDT+F N K + H IT PN++LRI G +LY++R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQ-SVNFVPGMTLSQFDLI 323
LTI A+C ++L NFPMD SCPL SY Y +++VYQW+ S V L QF +
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFV 243
Query: 324 SFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
GD+ V+ V F+L R GYF IQ Y+PC LIVVLSWVSFWI+++
Sbjct: 244 GLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKD 299
Score = 36.3 bits (80), Expect = 0.27
Identities = 15/35 (42%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
Query: 488 RGHINSVSHIDRAARVLFPASFALLNLFYWMIYAF 522
R HI ++ +D AR+ FP +F L NL YW+ Y +
Sbjct: 433 RIHIR-IAKMDSYARIFFPTAFCLFNLVYWVSYLY 466
>BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor, gamma 2, isoform 2 precursor protein.
Length = 467
Score = 227 bits (555), Expect = 8e-59
Identities = 104/236 (44%), Positives = 148/236 (62%), Gaps = 2/236 (0%)
Query: 145 NITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 204
++T +L NLL+ Y+N P G PT++ T++ + S+GPV+ ++M+Y++D +F Q W D
Sbjct: 65 DVTVILNNLLEGYDNKLRPDIGVK-PTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYD 123
Query: 205 TRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
RL F I+ L L+ M+ +IW PDT+F N K + H IT PN++LRI G +LY++R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQ-SVNFVPGMTLSQFDLI 323
LTI A+C ++L NFPMD SCPL SY Y +++VYQW+ S V L QF +
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFV 243
Query: 324 SFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
GD+ V+ V F+L R GYF IQ Y+PC LIVVLSWVSFWI+++
Sbjct: 244 GLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKD 299
Score = 36.3 bits (80), Expect = 0.27
Identities = 15/35 (42%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
Query: 488 RGHINSVSHIDRAARVLFPASFALLNLFYWMIYAF 522
R HI ++ +D AR+ FP +F L NL YW+ Y +
Sbjct: 433 RIHIR-IAKMDSYARIFFPTAFCLFNLVYWVSYLY 466
>BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 475
Score = 227 bits (555), Expect = 8e-59
Identities = 104/236 (44%), Positives = 148/236 (62%), Gaps = 2/236 (0%)
Query: 145 NITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 204
++T +L NLL+ Y+N P G PT++ T++ + S+GPV+ ++M+Y++D +F Q W D
Sbjct: 65 DVTVILNNLLEGYDNKLRPDIGVK-PTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYD 123
Query: 205 TRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
RL F I+ L L+ M+ +IW PDT+F N K + H IT PN++LRI G +LY++R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQ-SVNFVPGMTLSQFDLI 323
LTI A+C ++L NFPMD SCPL SY Y +++VYQW+ S V L QF +
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFV 243
Query: 324 SFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
GD+ V+ V F+L R GYF IQ Y+PC LIVVLSWVSFWI+++
Sbjct: 244 GLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKD 299
Score = 36.3 bits (80), Expect = 0.27
Identities = 15/35 (42%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
Query: 488 RGHINSVSHIDRAARVLFPASFALLNLFYWMIYAF 522
R HI ++ +D AR+ FP +F L NL YW+ Y +
Sbjct: 441 RIHIR-IAKMDSYARIFFPTAFCLFNLVYWVSYLY 474
>AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor gamma 2 protein.
Length = 467
Score = 227 bits (555), Expect = 8e-59
Identities = 104/236 (44%), Positives = 148/236 (62%), Gaps = 2/236 (0%)
Query: 145 NITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 204
++T +L NLL+ Y+N P G PT++ T++ + S+GPV+ ++M+Y++D +F Q W D
Sbjct: 65 DVTVILNNLLEGYDNKLRPDIGVK-PTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYD 123
Query: 205 TRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
RL F I+ L L+ M+ +IW PDT+F N K + H IT PN++LRI G +LY++R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQ-SVNFVPGMTLSQFDLI 323
LTI A+C ++L NFPMD SCPL SY Y +++VYQW+ S V L QF +
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFV 243
Query: 324 SFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
GD+ V+ V F+L R GYF IQ Y+PC LIVVLSWVSFWI+++
Sbjct: 244 GLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKD 299
Score = 36.3 bits (80), Expect = 0.27
Identities = 15/35 (42%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
Query: 488 RGHINSVSHIDRAARVLFPASFALLNLFYWMIYAF 522
R HI ++ +D AR+ FP +F L NL YW+ Y +
Sbjct: 433 RIHIR-IAKMDSYARIFFPTAFCLFNLVYWVSYLY 466
>S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 223 bits (546), Expect = 9e-58
Identities = 105/236 (44%), Positives = 145/236 (61%), Gaps = 2/236 (0%)
Query: 145 NITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 204
++T +L LL+ Y+ P G PTV+ +I + S+GPVS ++M+Y +D +F Q W D
Sbjct: 46 DVTLILNKLLREYDKKLRPDIGIK-PTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 205 TRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
+RL F ++ L+L+ M+ IW PDT F N K + H IT PN+LLRI G ILY++R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW-QNSQSVNFVPGMTLSQFDLI 323
LTI A+C ++L NFPMD SCPLI SY Y ++++Y+W +NS L QFD +
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFM 224
Query: 324 SFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
T GD+ V+ + F L R GYF IQ Y+PCIL VVLSWVSFWI ++
Sbjct: 225 GLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKD 280
Score = 35.5 bits (78), Expect = 0.48
Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
Query: 488 RGHINSVSHIDRAARVLFPASFALLNLFYWMIYAF 522
R HI+ + +D +RV FP SF L NL YW+ Y +
Sbjct: 433 RIHID-ILELDSYSRVFFPTSFLLFNLVYWVGYLY 466
>AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 223 bits (546), Expect = 9e-58
Identities = 105/236 (44%), Positives = 145/236 (61%), Gaps = 2/236 (0%)
Query: 145 NITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 204
++T +L LL+ Y+ P G PTV+ +I + S+GPVS ++M+Y +D +F Q W D
Sbjct: 46 DVTLILNKLLREYDKKLRPDIGIK-PTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 205 TRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
+RL F ++ L+L+ M+ IW PDT F N K + H IT PN+LLRI G ILY++R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW-QNSQSVNFVPGMTLSQFDLI 323
LTI A+C ++L NFPMD SCPLI SY Y ++++Y+W +NS L QFD +
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFM 224
Query: 324 SFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
T GD+ V+ + F L R GYF IQ Y+PCIL VVLSWVSFWI ++
Sbjct: 225 GLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKD 280
Score = 35.5 bits (78), Expect = 0.48
Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
Query: 488 RGHINSVSHIDRAARVLFPASFALLNLFYWMIYAF 522
R HI+ + +D +RV FP SF L NL YW+ Y +
Sbjct: 433 RIHID-ILELDSYSRVFFPTSFLLFNLVYWVGYLY 466
>AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 449
Score = 223 bits (546), Expect = 9e-58
Identities = 105/236 (44%), Positives = 145/236 (61%), Gaps = 2/236 (0%)
Query: 145 NITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 204
++T +L LL+ Y+ P G PTV+ +I + S+GPVS ++M+Y +D +F Q W D
Sbjct: 28 DVTLILNKLLREYDKKLRPDIGIK-PTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 86
Query: 205 TRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
+RL F ++ L+L+ M+ IW PDT F N K + H IT PN+LLRI G ILY++R
Sbjct: 87 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 146
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW-QNSQSVNFVPGMTLSQFDLI 323
LTI A+C ++L NFPMD SCPLI SY Y ++++Y+W +NS L QFD +
Sbjct: 147 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFM 206
Query: 324 SFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
T GD+ V+ + F L R GYF IQ Y+PCIL VVLSWVSFWI ++
Sbjct: 207 GLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKD 262
Score = 35.5 bits (78), Expect = 0.48
Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
Query: 488 RGHINSVSHIDRAARVLFPASFALLNLFYWMIYAF 522
R HI+ + +D +RV FP SF L NL YW+ Y +
Sbjct: 415 RIHID-ILELDSYSRVFFPTSFLLFNLVYWVGYLY 448
>BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 1 protein.
Length = 465
Score = 215 bits (524), Expect = 4e-55
Identities = 101/236 (42%), Positives = 146/236 (61%), Gaps = 2/236 (0%)
Query: 145 NITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRD 204
+IT +L +LL+ Y+N P G PTV++T++ + S+GPV ++M+Y++D F Q W D
Sbjct: 63 DITQILNSLLQGYDNKLRPDIGVR-PTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFD 121
Query: 205 TRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
+RL F ++ L L+ M+ +IW PDT+F N + S H IT PN+LLRI G +LY++R
Sbjct: 122 SRLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLR 181
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQN-SQSVNFVPGMTLSQFDLI 323
LTI A+C ++L NFPMD SCPL SY Y ++ Y+W+ S V L QF +
Sbjct: 182 LTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFV 241
Query: 324 SFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
GD+ ++ + F+L R GYF IQ Y+PCIL VVLSWVSFWI+++
Sbjct: 242 GLRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKD 297
Score = 37.1 bits (82), Expect = 0.16
Identities = 16/35 (45%), Positives = 23/35 (65%), Gaps = 1/35 (2%)
Query: 488 RGHINSVSHIDRAARVLFPASFALLNLFYWMIYAF 522
R HI ++ ID +R+ FP +FAL NL YW+ Y +
Sbjct: 431 RIHIR-IAKIDSYSRIFFPTAFALFNLVYWVGYLY 464
>X13584-1|CAA31925.1| 354|Homo sapiens protein ( Human mRNA for
gamma-aminobutyric-acid receptor alpha-subunit (GABA-A
receptor alpha-subunit). ).
Length = 354
Score = 210 bits (513), Expect = 9e-54
Identities = 106/249 (42%), Positives = 155/249 (62%), Gaps = 20/249 (8%)
Query: 137 SINDAVSKN---ITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYS 193
S+ D + N T +L+ LL Y+N P G+ T V+T+I + S GPVS+ DM+Y+
Sbjct: 30 SLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERV-TEVKTDIFVTSFGPVSDHDMEYT 88
Query: 194 MDCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRI 253
+D +FRQ W+D RL F GP+ L L+ M +IW PDT+ +PNKLLRI
Sbjct: 89 IDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTF-------------MPNKLLRI 135
Query: 254 SQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFV- 312
++ G +LY+MRLT++A+CPM L +FPMD +CPL GSYAY+ ++VY+W + + V
Sbjct: 136 TEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPAHSVVV 195
Query: 313 --PGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLS 370
G L+Q+DL+ + G++ V+ F+LKR GYF+IQ Y+PCI+ V+LS
Sbjct: 196 AEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS 255
Query: 371 WVSFWIHRE 379
VSFW++RE
Sbjct: 256 QVSFWLNRE 264
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 207 bits (506), Expect = 7e-53
Identities = 126/372 (33%), Positives = 186/372 (50%), Gaps = 19/372 (5%)
Query: 167 KGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLG-PIRSLSLSIKMLER 225
KG P V NI I S G ++E MDY ++ + RQ W D RL++ P SL L ML+
Sbjct: 66 KGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDS 125
Query: 226 IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSC 285
IW+PD +F N K + H +T NKLLRI ++G++LYS+RLT+ CPM+L+NFPMD Q+C
Sbjct: 126 IWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTC 185
Query: 286 PLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDL-ISFPYRNFTFTRREGDFSVLQV 344
+ L S+ Y+ L+++WQ+ V G+TL QF L R T G F+ ++V
Sbjct: 186 IMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEV 245
Query: 345 SFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVIDDSEWEELIEEVGGDXX 404
F+L+R GY+LIQ+Y+P +LIV+LSWVSFWI+ + + + + + + G
Sbjct: 246 RFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRA 305
Query: 405 XXXXXXXXXXXXXXXXTNNLSMPSQSSNPTTSDNLETEQPVAVRLTMERTTQ-TETRVPR 463
L + S + + + +R +R + E R R
Sbjct: 306 SLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKDDEVRESR 365
Query: 464 WRQLLY----CLAGDDRY-----RRQRQREAGSRGHINSVSHIDRA------ARVLFPAS 508
+ Y CL D Q S + V IDRA +R FP +
Sbjct: 366 FSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKV-FIDRAKKIDTISRACFPLA 424
Query: 509 FALLNLFYWMIY 520
F + N+FYW+IY
Sbjct: 425 FLIFNIFYWVIY 436
>M82919-1|AAA52511.1| 473|Homo sapiens GABA-alpha receptor beta-3
subunit protein.
Length = 473
Score = 207 bits (505), Expect = 9e-53
Identities = 97/254 (38%), Positives = 156/254 (61%), Gaps = 3/254 (1%)
Query: 136 RSINDAVSKN-ITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSM 194
+S+ND + + + ++ LLK Y+ P G G P V NI I S+ VSE++MDY++
Sbjct: 26 QSVNDPGNMSFVKETVDKLLKGYDIRLRPDFG-GPPVCVGMNIDIASIDMVSEVNMDYTL 84
Query: 195 DCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRIS 254
YF+QYWRD RL++ G +L+L ++ +++W PDTYF N K S+VH +TV N+++R+
Sbjct: 85 TMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLH 144
Query: 255 QHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQ-NSQSVNFVP 313
G +LY +R+T A C M+LR +P+D Q+C L + SY Y+ + + W+ ++V V
Sbjct: 145 PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVE 204
Query: 314 GMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVS 373
+ L QF ++ + G + L +SF LKR+ GYF++Q Y+P ILI +LSWVS
Sbjct: 205 RIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVS 264
Query: 374 FWIHREVGSGEIVI 387
FWI+ + + + +
Sbjct: 265 FWINYDASAARVAL 278
Score = 38.3 bits (85), Expect = 0.068
Identities = 14/30 (46%), Positives = 22/30 (73%)
Query: 491 INSVSHIDRAARVLFPASFALLNLFYWMIY 520
+ V+ IDR +R++FP +F+L NL YW+ Y
Sbjct: 442 LTDVNAIDRWSRIVFPFTFSLFNLVYWLYY 471
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 206 bits (502), Expect = 2e-52
Identities = 96/221 (43%), Positives = 140/221 (63%), Gaps = 2/221 (0%)
Query: 167 KGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLG-PIRSLSLSIKMLER 225
KG P V NI I S G ++E MDY ++ + RQ W D RL++ P SL L ML+
Sbjct: 61 KGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDS 120
Query: 226 IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSC 285
IW+PD +F N K ++ H IT NKLLRIS++G++LYS+R+T+ CPM+L+NFPMD Q+C
Sbjct: 121 IWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTC 180
Query: 286 PLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDL-ISFPYRNFTFTRREGDFSVLQV 344
+ L S+ Y+ L+++WQ +V G+TL QF L R T G F+ ++
Sbjct: 181 IMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEA 240
Query: 345 SFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEI 385
F+L+R GY+LIQ+Y+P +LIV+LSW+SFWI+ + +
Sbjct: 241 RFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARV 281
Score = 37.1 bits (82), Expect = 0.16
Identities = 13/30 (43%), Positives = 20/30 (66%)
Query: 491 INSVSHIDRAARVLFPASFALLNLFYWMIY 520
I ID+ +R+ FP +F + N+FYW+IY
Sbjct: 409 IQRAKKIDKISRIGFPMAFLIFNMFYWIIY 438
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 206 bits (502), Expect = 2e-52
Identities = 97/223 (43%), Positives = 140/223 (62%), Gaps = 2/223 (0%)
Query: 167 KGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLG-PIRSLSLSIKMLER 225
KG P V NI I S G V+E MDY ++ + RQ W D+RL++ P SL L ML+
Sbjct: 67 KGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDS 126
Query: 226 IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSC 285
IW+PD +F N K + H +T NKLLRIS++G +LYS+RLT+ CPM+L+NFPMD Q+C
Sbjct: 127 IWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTC 186
Query: 286 PLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRNF-TFTRREGDFSVLQV 344
+ L S+ Y+ L+++W + V G+TL QF L + T G F+ ++V
Sbjct: 187 TMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEV 246
Query: 345 SFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVI 387
F+L+R GY+LIQ+Y+P +LIV+LSWVSFWI+ + + +
Sbjct: 247 KFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVAL 289
Score = 34.7 bits (76), Expect = 0.83
Identities = 12/37 (32%), Positives = 21/37 (56%)
Query: 484 EAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
+A + ++ ID +R FP +F + N+FYW+ Y
Sbjct: 405 DAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 206 bits (502), Expect = 2e-52
Identities = 97/223 (43%), Positives = 140/223 (62%), Gaps = 2/223 (0%)
Query: 167 KGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLG-PIRSLSLSIKMLER 225
KG P V NI I S G V+E MDY ++ + RQ W D+RL++ P SL L ML+
Sbjct: 67 KGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDS 126
Query: 226 IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSC 285
IW+PD +F N K + H +T NKLLRIS++G +LYS+RLT+ CPM+L+NFPMD Q+C
Sbjct: 127 IWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTC 186
Query: 286 PLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRNF-TFTRREGDFSVLQV 344
+ L S+ Y+ L+++W + V G+TL QF L + T G F+ ++V
Sbjct: 187 TMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEV 246
Query: 345 SFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVI 387
F+L+R GY+LIQ+Y+P +LIV+LSWVSFWI+ + + +
Sbjct: 247 KFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVAL 289
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 206 bits (502), Expect = 2e-52
Identities = 96/221 (43%), Positives = 140/221 (63%), Gaps = 2/221 (0%)
Query: 167 KGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLG-PIRSLSLSIKMLER 225
KG P V NI I S G ++E MDY ++ + RQ W D RL++ P SL L ML+
Sbjct: 61 KGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDS 120
Query: 226 IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSC 285
IW+PD +F N K ++ H IT NKLLRIS++G++LYS+R+T+ CPM+L+NFPMD Q+C
Sbjct: 121 IWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTC 180
Query: 286 PLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDL-ISFPYRNFTFTRREGDFSVLQV 344
+ L S+ Y+ L+++WQ +V G+TL QF L R T G F+ ++
Sbjct: 181 IMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEA 240
Query: 345 SFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEI 385
F+L+R GY+LIQ+Y+P +LIV+LSW+SFWI+ + +
Sbjct: 241 RFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARV 281
Score = 37.1 bits (82), Expect = 0.16
Identities = 13/30 (43%), Positives = 20/30 (66%)
Query: 491 INSVSHIDRAARVLFPASFALLNLFYWMIY 520
I ID+ +R+ FP +F + N+FYW+IY
Sbjct: 417 IQRAKKIDKISRIGFPMAFLIFNMFYWIIY 446
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia, stiff man syndrome)
protein.
Length = 449
Score = 206 bits (502), Expect = 2e-52
Identities = 96/221 (43%), Positives = 140/221 (63%), Gaps = 2/221 (0%)
Query: 167 KGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLG-PIRSLSLSIKMLER 225
KG P V NI I S G ++E MDY ++ + RQ W D RL++ P SL L ML+
Sbjct: 61 KGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDS 120
Query: 226 IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSC 285
IW+PD +F N K ++ H IT NKLLRIS++G++LYS+R+T+ CPM+L+NFPMD Q+C
Sbjct: 121 IWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTC 180
Query: 286 PLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDL-ISFPYRNFTFTRREGDFSVLQV 344
+ L S+ Y+ L+++WQ +V G+TL QF L R T G F+ ++
Sbjct: 181 IMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEA 240
Query: 345 SFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEI 385
F+L+R GY+LIQ+Y+P +LIV+LSW+SFWI+ + +
Sbjct: 241 RFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARV 281
Score = 37.1 bits (82), Expect = 0.16
Identities = 13/30 (43%), Positives = 20/30 (66%)
Query: 491 INSVSHIDRAARVLFPASFALLNLFYWMIY 520
I ID+ +R+ FP +F + N+FYW+IY
Sbjct: 409 IQRAKKIDKISRIGFPMAFLIFNMFYWIIY 438
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 206 bits (502), Expect = 2e-52
Identities = 97/223 (43%), Positives = 140/223 (62%), Gaps = 2/223 (0%)
Query: 167 KGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLG-PIRSLSLSIKMLER 225
KG P V NI I S G V+E MDY ++ + RQ W D+RL++ P SL L ML+
Sbjct: 67 KGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDS 126
Query: 226 IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSC 285
IW+PD +F N K + H +T NKLLRIS++G +LYS+RLT+ CPM+L+NFPMD Q+C
Sbjct: 127 IWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTC 186
Query: 286 PLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRNF-TFTRREGDFSVLQV 344
+ L S+ Y+ L+++W + V G+TL QF L + T G F+ ++V
Sbjct: 187 TMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEV 246
Query: 345 SFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVI 387
F+L+R GY+LIQ+Y+P +LIV+LSWVSFWI+ + + +
Sbjct: 247 KFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVAL 289
Score = 34.7 bits (76), Expect = 0.83
Identities = 12/37 (32%), Positives = 21/37 (56%)
Query: 484 EAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
+A + ++ ID +R FP +F + N+FYW+ Y
Sbjct: 405 DAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 206 bits (502), Expect = 2e-52
Identities = 97/223 (43%), Positives = 140/223 (62%), Gaps = 2/223 (0%)
Query: 167 KGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLG-PIRSLSLSIKMLER 225
KG P V NI I S G V+E MDY ++ + RQ W D+RL++ P SL L ML+
Sbjct: 67 KGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDS 126
Query: 226 IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSC 285
IW+PD +F N K + H +T NKLLRIS++G +LYS+RLT+ CPM+L+NFPMD Q+C
Sbjct: 127 IWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTC 186
Query: 286 PLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRNF-TFTRREGDFSVLQV 344
+ L S+ Y+ L+++W + V G+TL QF L + T G F+ ++V
Sbjct: 187 TMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEV 246
Query: 345 SFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVI 387
F+L+R GY+LIQ+Y+P +LIV+LSWVSFWI+ + + +
Sbjct: 247 KFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVAL 289
Score = 34.7 bits (76), Expect = 0.83
Identities = 12/37 (32%), Positives = 21/37 (56%)
Query: 484 EAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
+A + ++ ID +R FP +F + N+FYW+ Y
Sbjct: 405 DAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 206 bits (502), Expect = 2e-52
Identities = 97/223 (43%), Positives = 140/223 (62%), Gaps = 2/223 (0%)
Query: 167 KGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLG-PIRSLSLSIKMLER 225
KG P V NI I S G V+E MDY ++ + RQ W D+RL++ P SL L ML+
Sbjct: 67 KGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDS 126
Query: 226 IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSC 285
IW+PD +F N K + H +T NKLLRIS++G +LYS+RLT+ CPM+L+NFPMD Q+C
Sbjct: 127 IWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTC 186
Query: 286 PLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRNF-TFTRREGDFSVLQV 344
+ L S+ Y+ L+++W + V G+TL QF L + T G F+ ++V
Sbjct: 187 TMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEV 246
Query: 345 SFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVI 387
F+L+R GY+LIQ+Y+P +LIV+LSWVSFWI+ + + +
Sbjct: 247 KFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVAL 289
Score = 34.7 bits (76), Expect = 0.83
Identities = 12/37 (32%), Positives = 21/37 (56%)
Query: 484 EAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
+A + ++ ID +R FP +F + N+FYW+ Y
Sbjct: 405 DAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 205 bits (501), Expect = 3e-52
Identities = 96/223 (43%), Positives = 140/223 (62%), Gaps = 2/223 (0%)
Query: 167 KGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLG-PIRSLSLSIKMLER 225
KG P V NI I S G ++E MDY ++ + RQ W D+RL++ P SL L ML+
Sbjct: 67 KGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDS 126
Query: 226 IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSC 285
IW+PD +F N K + H +T NKLLRIS++G +LYS+RLT+ CPM+L+NFPMD Q+C
Sbjct: 127 IWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTC 186
Query: 286 PLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRNF-TFTRREGDFSVLQV 344
+ L S+ Y+ L+++W + V G+TL QF L + T G F+ ++V
Sbjct: 187 TMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEV 246
Query: 345 SFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVI 387
F+L+R GY+LIQ+Y+P +LIV+LSWVSFWI+ + + +
Sbjct: 247 KFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVAL 289
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 205 bits (501), Expect = 3e-52
Identities = 96/223 (43%), Positives = 140/223 (62%), Gaps = 2/223 (0%)
Query: 167 KGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLG-PIRSLSLSIKMLER 225
KG P V NI I S G ++E MDY ++ + RQ W D+RL++ P SL L ML+
Sbjct: 67 KGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDS 126
Query: 226 IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSC 285
IW+PD +F N K + H +T NKLLRIS++G +LYS+RLT+ CPM+L+NFPMD Q+C
Sbjct: 127 IWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTC 186
Query: 286 PLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRNF-TFTRREGDFSVLQV 344
+ L S+ Y+ L+++W + V G+TL QF L + T G F+ ++V
Sbjct: 187 TMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEV 246
Query: 345 SFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVI 387
F+L+R GY+LIQ+Y+P +LIV+LSWVSFWI+ + + +
Sbjct: 247 KFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVAL 289
Score = 34.7 bits (76), Expect = 0.83
Identities = 12/37 (32%), Positives = 21/37 (56%)
Query: 484 EAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
+A + ++ ID +R FP +F + N+FYW+ Y
Sbjct: 405 DAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 205 bits (501), Expect = 3e-52
Identities = 96/223 (43%), Positives = 140/223 (62%), Gaps = 2/223 (0%)
Query: 167 KGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLG-PIRSLSLSIKMLER 225
KG P V NI I S G ++E MDY ++ + RQ W D+RL++ P SL L ML+
Sbjct: 67 KGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDS 126
Query: 226 IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSC 285
IW+PD +F N K + H +T NKLLRIS++G +LYS+RLT+ CPM+L+NFPMD Q+C
Sbjct: 127 IWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTC 186
Query: 286 PLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRNF-TFTRREGDFSVLQV 344
+ L S+ Y+ L+++W + V G+TL QF L + T G F+ ++V
Sbjct: 187 TMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEV 246
Query: 345 SFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVI 387
F+L+R GY+LIQ+Y+P +LIV+LSWVSFWI+ + + +
Sbjct: 247 KFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVAL 289
Score = 34.7 bits (76), Expect = 0.83
Identities = 12/37 (32%), Positives = 21/37 (56%)
Query: 484 EAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
+A + ++ ID +R FP +F + N+FYW+ Y
Sbjct: 405 DAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 204 bits (499), Expect = 5e-52
Identities = 97/223 (43%), Positives = 140/223 (62%), Gaps = 2/223 (0%)
Query: 167 KGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLG-PIRSLSLSIKMLER 225
KG P V NI I S G ++E MDY ++ + RQ W D RL++ P SL L ML+
Sbjct: 66 KGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDS 125
Query: 226 IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSC 285
IW+PD +F N K + H +T NKLLRI ++G++LYS+RLT+ CPM+L+NFPMD Q+C
Sbjct: 126 IWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTC 185
Query: 286 PLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDL-ISFPYRNFTFTRREGDFSVLQV 344
+ L S+ Y+ L+++WQ+ V G+TL QF L R T G F+ ++V
Sbjct: 186 IMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEV 245
Query: 345 SFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVI 387
F+L+R GY+LIQ+Y+P +LIV+LSWVSFWI+ + + +
Sbjct: 246 RFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVAL 288
Score = 36.3 bits (80), Expect = 0.27
Identities = 13/30 (43%), Positives = 19/30 (63%)
Query: 491 INSVSHIDRAARVLFPASFALLNLFYWMIY 520
I+ ID +R FP +F + N+FYW+IY
Sbjct: 422 IDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 204 bits (499), Expect = 5e-52
Identities = 97/223 (43%), Positives = 140/223 (62%), Gaps = 2/223 (0%)
Query: 167 KGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLG-PIRSLSLSIKMLER 225
KG P V NI I S G ++E MDY ++ + RQ W D RL++ P SL L ML+
Sbjct: 66 KGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDS 125
Query: 226 IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSC 285
IW+PD +F N K + H +T NKLLRI ++G++LYS+RLT+ CPM+L+NFPMD Q+C
Sbjct: 126 IWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTC 185
Query: 286 PLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDL-ISFPYRNFTFTRREGDFSVLQV 344
+ L S+ Y+ L+++WQ+ V G+TL QF L R T G F+ ++V
Sbjct: 186 IMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEV 245
Query: 345 SFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVI 387
F+L+R GY+LIQ+Y+P +LIV+LSWVSFWI+ + + +
Sbjct: 246 RFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVAL 288
Score = 36.3 bits (80), Expect = 0.27
Identities = 13/30 (43%), Positives = 19/30 (63%)
Query: 491 INSVSHIDRAARVLFPASFALLNLFYWMIY 520
I+ ID +R FP +F + N+FYW+IY
Sbjct: 422 IDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
>BC010641-1|AAH10641.1| 473|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 3 protein.
Length = 473
Score = 204 bits (498), Expect = 6e-52
Identities = 96/254 (37%), Positives = 155/254 (61%), Gaps = 3/254 (1%)
Query: 136 RSINDAVSKN-ITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSM 194
+S+ND + + + ++ LLK Y+ P G G P V NI I S+ VSE++MDY++
Sbjct: 26 QSVNDPGNMSFVKETVDKLLKGYDIRLRPDFG-GPPVCVGMNIDIASIDMVSEVNMDYTL 84
Query: 195 DCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRIS 254
YF+QYWRD RL++ G +L+L ++ +++W PDTYF N K S+VH +TV N+++R+
Sbjct: 85 TMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLH 144
Query: 255 QHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQ-NSQSVNFVP 313
G +LY +R+T A C M+LR +P+D +C L + SY Y+ + + W+ ++V V
Sbjct: 145 PDGTVLYGLRITTTAACMMDLRRYPLDELNCTLEIESYGYTTDDIEFYWRGGDKAVTGVE 204
Query: 314 GMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVS 373
+ L QF ++ + G + L +SF LKR+ GYF++Q Y+P ILI +LSWVS
Sbjct: 205 RIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVS 264
Query: 374 FWIHREVGSGEIVI 387
FWI+ + + + +
Sbjct: 265 FWINYDASAARVAL 278
Score = 38.3 bits (85), Expect = 0.068
Identities = 14/30 (46%), Positives = 22/30 (73%)
Query: 491 INSVSHIDRAARVLFPASFALLNLFYWMIY 520
+ V+ IDR +R++FP +F+L NL YW+ Y
Sbjct: 442 LTDVNAIDRWSRIVFPFTFSLFNLVYWLYY 471
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 203 bits (496), Expect = 1e-51
Identities = 96/254 (37%), Positives = 154/254 (60%), Gaps = 3/254 (1%)
Query: 136 RSINDAVSKNITS-VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSM 194
+S+ND + ++ ++ LLK Y+ P G G P V NI I S+ VSE++MDY++
Sbjct: 25 QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFG-GPPVAVGMNIDIASIDMVSEVNMDYTL 83
Query: 195 DCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRIS 254
YF+Q WRD RLS+ +L+L ++ +++W PDTYF N K S+VH +TV N+++R+
Sbjct: 84 TMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLH 143
Query: 255 QHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQ-NSQSVNFVP 313
G +LY +R+T A C M+LR +P+D Q+C L + SY Y+ + + W+ + +V V
Sbjct: 144 PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVT 203
Query: 314 GMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVS 373
+ L QF ++ + G + L +SF LKR+ GYF++Q Y+P ILI +LSWVS
Sbjct: 204 KIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVS 263
Query: 374 FWIHREVGSGEIVI 387
FWI+ + + + +
Sbjct: 264 FWINYDASAARVAL 277
Score = 35.9 bits (79), Expect = 0.36
Identities = 15/45 (33%), Positives = 25/45 (55%)
Query: 476 RYRRQRQREAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
R RR+ + + + V+ IDR +R+ FP F+ N+ YW+ Y
Sbjct: 428 RLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYY 472
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 203 bits (496), Expect = 1e-51
Identities = 96/254 (37%), Positives = 154/254 (60%), Gaps = 3/254 (1%)
Query: 136 RSINDAVSKNITS-VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSM 194
+S+ND + ++ ++ LLK Y+ P G G P V NI I S+ VSE++MDY++
Sbjct: 25 QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFG-GPPVAVGMNIDIASIDMVSEVNMDYTL 83
Query: 195 DCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRIS 254
YF+Q WRD RLS+ +L+L ++ +++W PDTYF N K S+VH +TV N+++R+
Sbjct: 84 TMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLH 143
Query: 255 QHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQ-NSQSVNFVP 313
G +LY +R+T A C M+LR +P+D Q+C L + SY Y+ + + W+ + +V V
Sbjct: 144 PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVT 203
Query: 314 GMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVS 373
+ L QF ++ + G + L +SF LKR+ GYF++Q Y+P ILI +LSWVS
Sbjct: 204 KIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVS 263
Query: 374 FWIHREVGSGEIVI 387
FWI+ + + + +
Sbjct: 264 FWINYDASAARVAL 277
Score = 35.9 bits (79), Expect = 0.36
Identities = 15/45 (33%), Positives = 25/45 (55%)
Query: 476 RYRRQRQREAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
R RR+ + + + V+ IDR +R+ FP F+ N+ YW+ Y
Sbjct: 466 RLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYY 510
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 203 bits (496), Expect = 1e-51
Identities = 96/254 (37%), Positives = 154/254 (60%), Gaps = 3/254 (1%)
Query: 136 RSINDAVSKNITS-VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSM 194
+S+ND + ++ ++ LLK Y+ P G G P V NI I S+ VSE++MDY++
Sbjct: 25 QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFG-GPPVAVGMNIDIASIDMVSEVNMDYTL 83
Query: 195 DCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRIS 254
YF+Q WRD RLS+ +L+L ++ +++W PDTYF N K S+VH +TV N+++R+
Sbjct: 84 TMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLH 143
Query: 255 QHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQ-NSQSVNFVP 313
G +LY +R+T A C M+LR +P+D Q+C L + SY Y+ + + W+ + +V V
Sbjct: 144 PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVT 203
Query: 314 GMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVS 373
+ L QF ++ + G + L +SF LKR+ GYF++Q Y+P ILI +LSWVS
Sbjct: 204 KIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVS 263
Query: 374 FWIHREVGSGEIVI 387
FWI+ + + + +
Sbjct: 264 FWINYDASAARVAL 277
Score = 35.9 bits (79), Expect = 0.36
Identities = 15/45 (33%), Positives = 25/45 (55%)
Query: 476 RYRRQRQREAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
R RR+ + + + V+ IDR +R+ FP F+ N+ YW+ Y
Sbjct: 428 RLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYY 472
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 203 bits (496), Expect = 1e-51
Identities = 96/254 (37%), Positives = 154/254 (60%), Gaps = 3/254 (1%)
Query: 136 RSINDAVSKNITS-VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSM 194
+S+ND + ++ ++ LLK Y+ P G G P V NI I S+ VSE++MDY++
Sbjct: 25 QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFG-GPPVAVGMNIDIASIDMVSEVNMDYTL 83
Query: 195 DCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRIS 254
YF+Q WRD RLS+ +L+L ++ +++W PDTYF N K S+VH +TV N+++R+
Sbjct: 84 TMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLH 143
Query: 255 QHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQ-NSQSVNFVP 313
G +LY +R+T A C M+LR +P+D Q+C L + SY Y+ + + W+ + +V V
Sbjct: 144 PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVT 203
Query: 314 GMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVS 373
+ L QF ++ + G + L +SF LKR+ GYF++Q Y+P ILI +LSWVS
Sbjct: 204 KIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVS 263
Query: 374 FWIHREVGSGEIVI 387
FWI+ + + + +
Sbjct: 264 FWINYDASAARVAL 277
Score = 35.9 bits (79), Expect = 0.36
Identities = 15/45 (33%), Positives = 25/45 (55%)
Query: 476 RYRRQRQREAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
R RR+ + + + V+ IDR +R+ FP F+ N+ YW+ Y
Sbjct: 428 RLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYY 472
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 203 bits (496), Expect = 1e-51
Identities = 96/254 (37%), Positives = 154/254 (60%), Gaps = 3/254 (1%)
Query: 136 RSINDAVSKNITS-VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSM 194
+S+ND + ++ ++ LLK Y+ P G G P V NI I S+ VSE++MDY++
Sbjct: 25 QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFG-GPPVAVGMNIDIASIDMVSEVNMDYTL 83
Query: 195 DCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRIS 254
YF+Q WRD RLS+ +L+L ++ +++W PDTYF N K S+VH +TV N+++R+
Sbjct: 84 TMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLH 143
Query: 255 QHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQ-NSQSVNFVP 313
G +LY +R+T A C M+LR +P+D Q+C L + SY Y+ + + W+ + +V V
Sbjct: 144 PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVT 203
Query: 314 GMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVS 373
+ L QF ++ + G + L +SF LKR+ GYF++Q Y+P ILI +LSWVS
Sbjct: 204 KIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVS 263
Query: 374 FWIHREVGSGEIVI 387
FWI+ + + + +
Sbjct: 264 FWINYDASAARVAL 277
Score = 35.9 bits (79), Expect = 0.36
Identities = 15/45 (33%), Positives = 25/45 (55%)
Query: 476 RYRRQRQREAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
R RR+ + + + V+ IDR +R+ FP F+ N+ YW+ Y
Sbjct: 428 RLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYY 472
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 203 bits (496), Expect = 1e-51
Identities = 96/254 (37%), Positives = 154/254 (60%), Gaps = 3/254 (1%)
Query: 136 RSINDAVSKNITS-VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSM 194
+S+ND + ++ ++ LLK Y+ P G G P V NI I S+ VSE++MDY++
Sbjct: 25 QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFG-GPPVAVGMNIDIASIDMVSEVNMDYTL 83
Query: 195 DCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRIS 254
YF+Q WRD RLS+ +L+L ++ +++W PDTYF N K S+VH +TV N+++R+
Sbjct: 84 TMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLH 143
Query: 255 QHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQ-NSQSVNFVP 313
G +LY +R+T A C M+LR +P+D Q+C L + SY Y+ + + W+ + +V V
Sbjct: 144 PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVT 203
Query: 314 GMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVS 373
+ L QF ++ + G + L +SF LKR+ GYF++Q Y+P ILI +LSWVS
Sbjct: 204 KIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVS 263
Query: 374 FWIHREVGSGEIVI 387
FWI+ + + + +
Sbjct: 264 FWINYDASAARVAL 277
Score = 35.9 bits (79), Expect = 0.36
Identities = 15/45 (33%), Positives = 25/45 (55%)
Query: 476 RYRRQRQREAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
R RR+ + + + V+ IDR +R+ FP F+ N+ YW+ Y
Sbjct: 428 RLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYY 472
>U66661-1|AAB49284.1| 506|Homo sapiens GABA-A receptor epsilon
subunit protein.
Length = 506
Score = 198 bits (483), Expect = 4e-50
Identities = 92/232 (39%), Positives = 138/232 (59%), Gaps = 2/232 (0%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L +L NY++ P G+ PTVV I + S+GP+S LDM+Y++D F Q W D RL
Sbjct: 74 ILNTILSNYDHKLRPGIGEK-PTVVTVEIAVNSLGPLSILDMEYTIDIIFSQTWYDERLC 132
Query: 209 FLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIK 268
+ SL L+ ++ ++W PDT+F N K ++ H IT+PN+++RI + G +LY++R+TI
Sbjct: 133 YNDTFESLVLNGNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTID 192
Query: 269 AKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQ-SVNFVPGMTLSQFDLISFPY 327
A C + + FPMD SCPL S++Y +++Y+W+N + +N L QFD
Sbjct: 193 AGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTGVSN 252
Query: 328 RNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
+ T GDF V+ + FN+ R GY Q YVP + +LSWVSFWI E
Sbjct: 253 KTEIITTPVGDFMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTE 304
>BC059376-1|AAH59376.1| 365|Homo sapiens GABRE protein protein.
Length = 365
Score = 198 bits (483), Expect = 4e-50
Identities = 92/232 (39%), Positives = 138/232 (59%), Gaps = 2/232 (0%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L +L NY++ P G+ PTVV I + S+GP+S LDM+Y++D F Q W D RL
Sbjct: 74 ILNTILSNYDHKLRPGIGEK-PTVVTVEIAVNSLGPLSILDMEYTIDIIFSQTWYDERLC 132
Query: 209 FLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIK 268
+ SL L+ ++ ++W PDT+F N K ++ H IT+PN+++RI + G +LY++R+TI
Sbjct: 133 YNDTFESLVLNGNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTID 192
Query: 269 AKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQ-SVNFVPGMTLSQFDLISFPY 327
A C + + FPMD SCPL S++Y +++Y+W+N + +N L QFD
Sbjct: 193 AGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTGVSN 252
Query: 328 RNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
+ T GDF V+ + FN+ R GY Q YVP + +LSWVSFWI E
Sbjct: 253 KTEIITTPVGDFMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTE 304
>BC047108-1|AAH47108.1| 365|Homo sapiens GABRE protein protein.
Length = 365
Score = 198 bits (483), Expect = 4e-50
Identities = 92/232 (39%), Positives = 138/232 (59%), Gaps = 2/232 (0%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L +L NY++ P G+ PTVV I + S+GP+S LDM+Y++D F Q W D RL
Sbjct: 74 ILNTILSNYDHKLRPGIGEK-PTVVTVEIAVNSLGPLSILDMEYTIDIIFSQTWYDERLC 132
Query: 209 FLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIK 268
+ SL L+ ++ ++W PDT+F N K ++ H IT+PN+++RI + G +LY++R+TI
Sbjct: 133 YNDTFESLVLNGNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTID 192
Query: 269 AKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQ-SVNFVPGMTLSQFDLISFPY 327
A C + + FPMD SCPL S++Y +++Y+W+N + +N L QFD
Sbjct: 193 AGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTGVSN 252
Query: 328 RNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
+ T GDF V+ + FN+ R GY Q YVP + +LSWVSFWI E
Sbjct: 253 KTEIITTPVGDFMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTE 304
>BC026337-1|AAH26337.1| 365|Homo sapiens GABRE protein protein.
Length = 365
Score = 198 bits (483), Expect = 4e-50
Identities = 92/232 (39%), Positives = 138/232 (59%), Gaps = 2/232 (0%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L +L NY++ P G+ PTVV I + S+GP+S LDM+Y++D F Q W D RL
Sbjct: 74 ILNTILSNYDHKLRPGIGEK-PTVVTVEIAVNSLGPLSILDMEYTIDIIFSQTWYDERLC 132
Query: 209 FLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIK 268
+ SL L+ ++ ++W PDT+F N K ++ H IT+PN+++RI + G +LY++R+TI
Sbjct: 133 YNDTFESLVLNGNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTID 192
Query: 269 AKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQ-SVNFVPGMTLSQFDLISFPY 327
A C + + FPMD SCPL S++Y +++Y+W+N + +N L QFD
Sbjct: 193 AGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTGVSN 252
Query: 328 RNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
+ T GDF V+ + FN+ R GY Q YVP + +LSWVSFWI E
Sbjct: 253 KTEIITTPVGDFMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTE 304
>Y09765-1|CAA70904.1| 506|Homo sapiens GABA receptor epsilon
subunit protein.
Length = 506
Score = 198 bits (482), Expect = 5e-50
Identities = 92/232 (39%), Positives = 138/232 (59%), Gaps = 2/232 (0%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L +L NY++ P G+ PTVV I + S+GP+S LDM+Y++D F Q W D RL
Sbjct: 74 ILNTILSNYDHKLRPGIGEK-PTVVTVEISVNSLGPLSILDMEYTIDIIFSQTWYDERLC 132
Query: 209 FLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIK 268
+ SL L+ ++ ++W PDT+F N K ++ H IT+PN+++RI + G +LY++R+TI
Sbjct: 133 YNDTFESLVLNGNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTID 192
Query: 269 AKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQ-SVNFVPGMTLSQFDLISFPY 327
A C + + FPMD SCPL S++Y +++Y+W+N + +N L QFD
Sbjct: 193 AGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTGVSN 252
Query: 328 RNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
+ T GDF V+ + FN+ R GY Q YVP + +LSWVSFWI E
Sbjct: 253 KTEIITTPVGDFMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTE 304
>U92283-1|AAB94645.1| 506|Homo sapiens GABA-A receptor epsilon
subunit protein.
Length = 506
Score = 198 bits (482), Expect = 5e-50
Identities = 92/232 (39%), Positives = 138/232 (59%), Gaps = 2/232 (0%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L +L NY++ P G+ PTVV I + S+GP+S LDM+Y++D F Q W D RL
Sbjct: 74 ILNTILSNYDHKLRPGIGEK-PTVVTVEISVNSLGPLSILDMEYTIDIIFSQTWYDERLC 132
Query: 209 FLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIK 268
+ SL L+ ++ ++W PDT+F N K ++ H IT+PN+++RI + G +LY++R+TI
Sbjct: 133 YNDTFESLVLNGNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTID 192
Query: 269 AKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQ-SVNFVPGMTLSQFDLISFPY 327
A C + + FPMD SCPL S++Y +++Y+W+N + +N L QFD
Sbjct: 193 AGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTGVSN 252
Query: 328 RNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
+ T GDF V+ + FN+ R GY Q YVP + +LSWVSFWI E
Sbjct: 253 KTEIITTPVGDFMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTE 304
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 196 bits (478), Expect = 2e-49
Identities = 90/243 (37%), Positives = 146/243 (60%), Gaps = 2/243 (0%)
Query: 146 ITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDT 205
+ ++ LLK Y+ P G G P V I + S+ VSE++MDY++ YF+Q W+D
Sbjct: 37 VKETVDRLLKGYDIRLRPDFG-GPPVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDK 95
Query: 206 RLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRL 265
RLS+ G +L+L ++ +++W PDTYF N K S+VH +TV N+++R+ G +LY +R+
Sbjct: 96 RLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRI 155
Query: 266 TIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQ-SVNFVPGMTLSQFDLIS 324
T A C M+LR +P+D Q+C L + SY Y+ + + W + +V V + L QF ++
Sbjct: 156 TTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVD 215
Query: 325 FPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGE 384
+ + G + L +SF LKR+ GYF++Q Y+P LI +LSWVSFWI+ + +
Sbjct: 216 YKMVSKKVEFTTGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAAR 275
Query: 385 IVI 387
+ +
Sbjct: 276 VAL 278
Score = 36.3 bits (80), Expect = 0.27
Identities = 15/45 (33%), Positives = 26/45 (57%)
Query: 476 RYRRQRQREAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
R RR+ + + V+ ID+ +R+ FP +F+L N+ YW+ Y
Sbjct: 428 RIRRRASQLKVKIPDLTDVNSIDKWSRMFFPITFSLFNVVYWLYY 472
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 196 bits (478), Expect = 2e-49
Identities = 90/243 (37%), Positives = 146/243 (60%), Gaps = 2/243 (0%)
Query: 146 ITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDT 205
+ ++ LLK Y+ P G G P V I + S+ VSE++MDY++ YF+Q W+D
Sbjct: 37 VKETVDRLLKGYDIRLRPDFG-GPPVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDK 95
Query: 206 RLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRL 265
RLS+ G +L+L ++ +++W PDTYF N K S+VH +TV N+++R+ G +LY +R+
Sbjct: 96 RLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRI 155
Query: 266 TIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQ-SVNFVPGMTLSQFDLIS 324
T A C M+LR +P+D Q+C L + SY Y+ + + W + +V V + L QF ++
Sbjct: 156 TTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVD 215
Query: 325 FPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGE 384
+ + G + L +SF LKR+ GYF++Q Y+P LI +LSWVSFWI+ + +
Sbjct: 216 YKMVSKKVEFTTGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAAR 275
Query: 385 IVI 387
+ +
Sbjct: 276 VAL 278
Score = 36.3 bits (80), Expect = 0.27
Identities = 15/45 (33%), Positives = 26/45 (57%)
Query: 476 RYRRQRQREAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
R RR+ + + V+ ID+ +R+ FP +F+L N+ YW+ Y
Sbjct: 428 RIRRRASQLKVKIPDLTDVNSIDKWSRMFFPITFSLFNVVYWLYY 472
>Y09763-1|CAA70903.1| 506|Homo sapiens GABRE protein.
Length = 506
Score = 195 bits (476), Expect = 3e-49
Identities = 91/232 (39%), Positives = 137/232 (59%), Gaps = 2/232 (0%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L +L NY++ P G+ PTVV I + S+GP+S LDM+Y++D F Q W D RL
Sbjct: 74 ILNTILSNYDHKLRPGIGEK-PTVVTVEISVNSLGPLSILDMEYTIDIIFSQTWYDERLC 132
Query: 209 FLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIK 268
+ SL L+ ++ ++W PDT+F N K ++ H IT+PN+++RI + G +LY++R+TI
Sbjct: 133 YNDTFESLVLNGNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTID 192
Query: 269 AKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQ-SVNFVPGMTLSQFDLISFPY 327
A C + + FPMD SCPL S++Y +++Y+W+N + +N L Q D
Sbjct: 193 AGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQLDFTGVSN 252
Query: 328 RNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
+ T GDF V+ + FN+ R GY Q YVP + +LSWVSFWI E
Sbjct: 253 KTEIITTPVGDFMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTE 304
>Y07637-1|CAA68914.1| 505|Homo sapiens putative GABA-gated chloride
channel protein.
Length = 505
Score = 195 bits (475), Expect = 4e-49
Identities = 92/232 (39%), Positives = 138/232 (59%), Gaps = 3/232 (1%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L +L NY++ P G+ PTVV I + S+GP+S LDM+Y++D F Q W D RL
Sbjct: 74 ILNTILSNYDHKLRPGIGEK-PTVVTVEIAVNSLGPLSILDMEYTIDIIFSQTWYDERLC 132
Query: 209 FLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIK 268
+ SL L+ ++ ++W PDT+F N K ++ H IT+PN+++RI + G +LY++R+TI
Sbjct: 133 YNDTFESLVLNGNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTID 192
Query: 269 AKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQ-SVNFVPGMTLSQFDLISFPY 327
A C + + FPMD SCPL S++Y +++Y+W+N + +N L QFD
Sbjct: 193 AGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTGVSN 252
Query: 328 RNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
+ T GDF V+ + FN+ R GY Q YVP + +LSWVSFWI E
Sbjct: 253 KTEIIT-TPGDFMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTE 303
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 192 bits (467), Expect = 3e-48
Identities = 94/222 (42%), Positives = 139/222 (62%), Gaps = 3/222 (1%)
Query: 167 KGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLG-PIRSLSLSIKMLER 225
KG P V NI I S +++ MDY ++ + RQ W D RLS+ P SL L ML+
Sbjct: 26 KGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDS 85
Query: 226 IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSC 285
IW+PD +F N K + H +T NKLLRI ++G++LYS+RLT+ C M+L+NFPMD Q+C
Sbjct: 86 IWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTC 145
Query: 286 PLILGSYAYSNQQLVYQW-QNSQSVNFVPGMTLSQFDLISFPYRN-FTFTRREGDFSVLQ 343
+ L S+ Y+ + LV++W +++ +V G+TL QF L T G F+ ++
Sbjct: 146 TMQLESFGYTMKDLVFEWLEDAPAVQVAEGLTLPQFILRDEKDLGCCTKHYNTGKFTCIE 205
Query: 344 VSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEI 385
V F+L+R GY+LIQ+Y+P +LIV+LSWVSFWI+ + +
Sbjct: 206 VKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARV 247
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 192 bits (467), Expect = 3e-48
Identities = 94/222 (42%), Positives = 139/222 (62%), Gaps = 3/222 (1%)
Query: 167 KGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLG-PIRSLSLSIKMLER 225
KG P V NI I S +++ MDY ++ + RQ W D RLS+ P SL L ML+
Sbjct: 26 KGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDS 85
Query: 226 IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSC 285
IW+PD +F N K + H +T NKLLRI ++G++LYS+RLT+ C M+L+NFPMD Q+C
Sbjct: 86 IWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTC 145
Query: 286 PLILGSYAYSNQQLVYQW-QNSQSVNFVPGMTLSQFDLISFPYRN-FTFTRREGDFSVLQ 343
+ L S+ Y+ + LV++W +++ +V G+TL QF L T G F+ ++
Sbjct: 146 TMQLESFGYTMKDLVFEWLEDAPAVQVAEGLTLPQFILRDEKDLGCCTKHYNTGKFTCIE 205
Query: 344 VSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEI 385
V F+L+R GY+LIQ+Y+P +LIV+LSWVSFWI+ + +
Sbjct: 206 VKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARV 247
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 191 bits (465), Expect = 6e-48
Identities = 89/243 (36%), Positives = 145/243 (59%), Gaps = 2/243 (0%)
Query: 146 ITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDT 205
+ ++ LLK Y+ P G G P V I + S+ VSE++MDY++ YF+Q W+D
Sbjct: 37 VKETVDRLLKGYDIRLRPDFG-GPPVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDK 95
Query: 206 RLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRL 265
RLS+ G +L+L ++ +++ PDTYF N K S+VH +TV N+++R+ G +LY +R+
Sbjct: 96 RLSYSGIPLNLTLDNRVADQLCVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRI 155
Query: 266 TIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQ-SVNFVPGMTLSQFDLIS 324
T A C M+LR +P+D Q+C L + SY Y+ + + W + +V V + L QF ++
Sbjct: 156 TTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVD 215
Query: 325 FPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGE 384
+ + G + L +SF LKR+ GYF++Q Y+P LI +LSWVSFWI+ + +
Sbjct: 216 YKMVSKKVEFTTGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAAR 275
Query: 385 IVI 387
+ +
Sbjct: 276 VAL 278
Score = 35.9 bits (79), Expect = 0.36
Identities = 15/45 (33%), Positives = 26/45 (57%)
Query: 476 RYRRQRQREAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
R RR+ + + V+ ID+ +R+ FP +F+L N+ YW+ Y
Sbjct: 428 RNRRRASQLKVKIPDLTDVNSIDKWSRMFFPITFSLFNVVYWLYY 472
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 188 bits (457), Expect = 6e-47
Identities = 86/198 (43%), Positives = 128/198 (64%), Gaps = 2/198 (1%)
Query: 190 MDYSMDCYFRQYWRDTRLSFLG-PIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPN 248
MDY ++ + RQ W D RL++ P SL L ML+ IW+PD +F N K ++ H IT N
Sbjct: 1 MDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDN 60
Query: 249 KLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQS 308
KLLRIS++G++LYS+R+T+ CPM+L+NFPMD Q+C + L S+ Y+ L+++WQ +
Sbjct: 61 KLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGA 120
Query: 309 VNFVPGMTLSQFDL-ISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIV 367
V G+TL QF L R T G F+ ++ F+L+R GY+LIQ+Y+P +LIV
Sbjct: 121 VQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIV 180
Query: 368 VLSWVSFWIHREVGSGEI 385
+LSW+SFWI+ + +
Sbjct: 181 ILSWISFWINMDAAPARV 198
Score = 37.1 bits (82), Expect = 0.16
Identities = 13/30 (43%), Positives = 20/30 (66%)
Query: 491 INSVSHIDRAARVLFPASFALLNLFYWMIY 520
I ID+ +R+ FP +F + N+FYW+IY
Sbjct: 326 IQRAKKIDKISRIGFPMAFLIFNMFYWIIY 355
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 182 bits (442), Expect = 4e-45
Identities = 86/229 (37%), Positives = 137/229 (59%), Gaps = 3/229 (1%)
Query: 150 LENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF 209
L+ L+ Y + P G G P V + + S+ +SE +M+Y+M + Q WRD+RLS+
Sbjct: 44 LDGLIAGYARNFRPGIG-GPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSY 102
Query: 210 LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKA 269
+L L + ++++W PDT+ N K ++ H +TV NKL+R+ G ILYS+R+T
Sbjct: 103 NHTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTV 162
Query: 270 KCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQS-VNFVPGMTLSQFDLISFPYR 328
C M+L +PMD Q C L L SY YS++ +VY W SQ ++ + + L+QF + S+ +
Sbjct: 163 ACDMDLAKYPMDEQECMLDLESYGYSSEDIVYYWSESQEHIHGLDKLQLAQFTITSYRFT 222
Query: 329 NFTFT-RREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
+ G F L + F+L+R+ G ++IQ Y+P +L+V +SWVSFWI
Sbjct: 223 TELMNFKSAGQFPRLSLHFHLRRNRGVYIIQSYMPSVLLVAMSWVSFWI 271
Score = 35.1 bits (77), Expect = 0.63
Identities = 14/25 (56%), Positives = 18/25 (72%)
Query: 497 IDRAARVLFPASFALLNLFYWMIYA 521
ID AR +FPA+FA +N+ YW YA
Sbjct: 427 IDIYARAVFPAAFAAVNVIYWAAYA 451
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 182 bits (442), Expect = 4e-45
Identities = 86/229 (37%), Positives = 137/229 (59%), Gaps = 3/229 (1%)
Query: 150 LENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF 209
L+ L+ Y + P G G P V + + S+ +SE +M+Y+M + Q WRD+RLS+
Sbjct: 44 LDGLIAGYARNFRPGIG-GPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSY 102
Query: 210 LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKA 269
+L L + ++++W PDT+ N K ++ H +TV NKL+R+ G ILYS+R+T
Sbjct: 103 NHTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTV 162
Query: 270 KCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQS-VNFVPGMTLSQFDLISFPYR 328
C M+L +PMD Q C L L SY YS++ +VY W SQ ++ + + L+QF + S+ +
Sbjct: 163 ACDMDLAKYPMDEQECMLDLESYGYSSEDIVYYWSESQEHIHGLDKLQLAQFTITSYRFT 222
Query: 329 NFTFT-RREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
+ G F L + F+L+R+ G ++IQ Y+P +L+V +SWVSFWI
Sbjct: 223 TELMNFKSAGQFPRLSLHFHLRRNRGVYIIQSYMPSVLLVAMSWVSFWI 271
Score = 35.1 bits (77), Expect = 0.63
Identities = 14/25 (56%), Positives = 18/25 (72%)
Query: 497 IDRAARVLFPASFALLNLFYWMIYA 521
ID AR +FPA+FA +N+ YW YA
Sbjct: 427 IDIYARAVFPAAFAAVNVIYWAAYA 451
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 182 bits (442), Expect = 4e-45
Identities = 86/229 (37%), Positives = 137/229 (59%), Gaps = 3/229 (1%)
Query: 150 LENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF 209
L+ L+ Y + P G G P V + + S+ +SE +M+Y+M + Q WRD+RLS+
Sbjct: 44 LDGLIAGYARNFRPGIG-GPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSY 102
Query: 210 LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKA 269
+L L + ++++W PDT+ N K ++ H +TV NKL+R+ G ILYS+R+T
Sbjct: 103 NHTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTV 162
Query: 270 KCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQS-VNFVPGMTLSQFDLISFPYR 328
C M+L +PMD Q C L L SY YS++ +VY W SQ ++ + + L+QF + S+ +
Sbjct: 163 ACDMDLAKYPMDEQECMLDLESYGYSSEDIVYYWSESQEHIHGLDKLQLAQFTITSYHFT 222
Query: 329 NFTFT-RREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
+ G F L + F+L+R+ G ++IQ Y+P +L+V +SWVSFWI
Sbjct: 223 TELMNFKSAGQFPRLSLHFHLRRNRGVYIIQSYMPSVLLVAMSWVSFWI 271
Score = 35.1 bits (77), Expect = 0.63
Identities = 14/25 (56%), Positives = 18/25 (72%)
Query: 497 IDRAARVLFPASFALLNLFYWMIYA 521
ID AR +FPA+FA +N+ YW YA
Sbjct: 427 IDIYARAVFPAAFAAVNVIYWAAYA 451
>M86868-1|AAA52510.1| 465|Homo sapiens gamma-amino butyric acid
protein.
Length = 465
Score = 179 bits (435), Expect = 3e-44
Identities = 86/225 (38%), Positives = 137/225 (60%), Gaps = 4/225 (1%)
Query: 157 YENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPI-RS 215
++ S P G G V ++ + S+ +SE+DMD++M Y R YW+D RL+F +S
Sbjct: 64 HDFSMRPAFG-GPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSASNKS 122
Query: 216 LSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMEL 275
++ +++++IW PD +F + K S+ H T N +LR+ G +LYSMR+T+ A C M+
Sbjct: 123 MTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDF 182
Query: 276 RNFPMDRQSCPLILGSYAYSNQQLVYQWQN-SQSVNFVPGMTLSQFDLISF-PYRNFTFT 333
+FP+D Q+C L L SYAY+++ L+ W+N +S+ ++LSQF + F F
Sbjct: 183 SHFPLDSQTCSLELESYAYTDEDLMLHWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFY 242
Query: 334 RREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHR 378
G ++ L ++F L+RH +FL+Q Y P L+V+LSWVSFWI R
Sbjct: 243 SSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDR 287
Score = 36.3 bits (80), Expect = 0.27
Identities = 18/53 (33%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
Query: 471 LAGDDRYRRQRQREAGSRG-HINSVSH-IDRAARVLFPASFALLNLFYWMIYA 521
L+G+ R++ G G I +H ID+ +R++FPAS+ NL YW +++
Sbjct: 413 LSGEANAARKKGLLKGQTGFRIFQNTHAIDKYSRLIFPASYIFFNLIYWSVFS 465
>BC130354-1|AAI30355.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, rho 2 protein.
Length = 465
Score = 178 bits (434), Expect = 3e-44
Identities = 86/225 (38%), Positives = 137/225 (60%), Gaps = 4/225 (1%)
Query: 157 YENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPI-RS 215
++ S P G G V ++ + S+ +SE+DMD++M Y R YW+D RL+F +S
Sbjct: 64 HDFSMRPAFG-GPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSASNKS 122
Query: 216 LSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMEL 275
++ +++++IW PD +F + K S+ H T N +LR+ G +LYSMR+T+ A C M+
Sbjct: 123 MTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDF 182
Query: 276 RNFPMDRQSCPLILGSYAYSNQQLVYQWQN-SQSVNFVPGMTLSQFDLISF-PYRNFTFT 333
+FP+D Q+C L L SYAY+++ L+ W+N +S+ ++LSQF + F F
Sbjct: 183 SHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFY 242
Query: 334 RREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHR 378
G ++ L ++F L+RH +FL+Q Y P L+V+LSWVSFWI R
Sbjct: 243 SSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDR 287
Score = 36.3 bits (80), Expect = 0.27
Identities = 18/53 (33%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
Query: 471 LAGDDRYRRQRQREAGSRG-HINSVSH-IDRAARVLFPASFALLNLFYWMIYA 521
L+G+ R++ G G I +H ID+ +R++FPAS+ NL YW +++
Sbjct: 413 LSGEANAARKKGLLKGQTGFRIFQNTHAIDKYSRLIFPASYIFFNLIYWSVFS 465
>BC130352-1|AAI30353.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, rho 2 protein.
Length = 465
Score = 178 bits (434), Expect = 3e-44
Identities = 86/225 (38%), Positives = 137/225 (60%), Gaps = 4/225 (1%)
Query: 157 YENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPI-RS 215
++ S P G G V ++ + S+ +SE+DMD++M Y R YW+D RL+F +S
Sbjct: 64 HDFSMRPAFG-GPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSASNKS 122
Query: 216 LSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMEL 275
++ +++++IW PD +F + K S+ H T N +LR+ G +LYSMR+T+ A C M+
Sbjct: 123 MTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDF 182
Query: 276 RNFPMDRQSCPLILGSYAYSNQQLVYQWQN-SQSVNFVPGMTLSQFDLISF-PYRNFTFT 333
+FP+D Q+C L L SYAY+++ L+ W+N +S+ ++LSQF + F F
Sbjct: 183 SHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFY 242
Query: 334 RREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHR 378
G ++ L ++F L+RH +FL+Q Y P L+V+LSWVSFWI R
Sbjct: 243 SSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDR 287
Score = 36.3 bits (80), Expect = 0.27
Identities = 18/53 (33%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
Query: 471 LAGDDRYRRQRQREAGSRG-HINSVSH-IDRAARVLFPASFALLNLFYWMIYA 521
L+G+ R++ G G I +H ID+ +R++FPAS+ NL YW +++
Sbjct: 413 LSGEANAARKKGLLKGQTGFRIFQNTHAIDKYSRLIFPASYIFFNLIYWSVFS 465
>AL121833-2|CAC07339.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, rho 2 protein.
Length = 465
Score = 178 bits (434), Expect = 3e-44
Identities = 86/225 (38%), Positives = 137/225 (60%), Gaps = 4/225 (1%)
Query: 157 YENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPI-RS 215
++ S P G G V ++ + S+ +SE+DMD++M Y R YW+D RL+F +S
Sbjct: 64 HDFSMRPAFG-GPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSASNKS 122
Query: 216 LSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMEL 275
++ +++++IW PD +F + K S+ H T N +LR+ G +LYSMR+T+ A C M+
Sbjct: 123 MTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDF 182
Query: 276 RNFPMDRQSCPLILGSYAYSNQQLVYQWQN-SQSVNFVPGMTLSQFDLISF-PYRNFTFT 333
+FP+D Q+C L L SYAY+++ L+ W+N +S+ ++LSQF + F F
Sbjct: 183 SHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFY 242
Query: 334 RREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHR 378
G ++ L ++F L+RH +FL+Q Y P L+V+LSWVSFWI R
Sbjct: 243 SSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDR 287
Score = 36.3 bits (80), Expect = 0.27
Identities = 18/53 (33%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
Query: 471 LAGDDRYRRQRQREAGSRG-HINSVSH-IDRAARVLFPASFALLNLFYWMIYA 521
L+G+ R++ G G I +H ID+ +R++FPAS+ NL YW +++
Sbjct: 413 LSGEANAARKKGLLKGQTGFRIFQNTHAIDKYSRLIFPASYIFFNLIYWSVFS 465
>M62400-1|AAA52509.1| 473|Homo sapiens gamma-aminobutyric acid
receptor type A rho-1 subunit protein.
Length = 473
Score = 176 bits (428), Expect = 2e-43
Identities = 87/241 (36%), Positives = 142/241 (58%), Gaps = 4/241 (1%)
Query: 142 VSKNITSVLENLLKNYENSQLPTHGKGYPTV-VQTNILIRSMGPVSELDMDYSMDCYFRQ 200
++K+ + E LL+ ++ G G P + V ++ + S+ +SE+DMD++M Y R
Sbjct: 61 ITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRH 120
Query: 201 YWRDTRLSFLGPIR-SLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDI 259
YW+D RLSF S++ +++++IW PD +F + K S++H T N +LR+ G +
Sbjct: 121 YWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKV 180
Query: 260 LYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW-QNSQSVNFVPGMTLS 318
LYS+R+T+ A C M+ FP+D Q+C L + SYAY+ L+ W + + S+ ++LS
Sbjct: 181 LYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLS 240
Query: 319 QFDLISF-PYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIH 377
QF + F F G ++ L ++F L+RH +FL+Q Y P L+V+LSWVSFWI
Sbjct: 241 QFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWID 300
Query: 378 R 378
R
Sbjct: 301 R 301
Score = 39.9 bits (89), Expect = 0.022
Identities = 18/58 (31%), Positives = 33/58 (56%), Gaps = 1/58 (1%)
Query: 465 RQLLYCLAGDDRYRRQRQREAGSRGHINSVSH-IDRAARVLFPASFALLNLFYWMIYA 521
R ++ +R QR+ + S + +H ID+ +R++FPA++ L NL YW I++
Sbjct: 416 RMMVQLTLASERSSPQRKSQRSSYVSMRIDTHAIDKYSRIIFPAAYILFNLIYWSIFS 473
>BC130344-1|AAI30345.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, rho 1 protein.
Length = 474
Score = 176 bits (428), Expect = 2e-43
Identities = 87/241 (36%), Positives = 142/241 (58%), Gaps = 4/241 (1%)
Query: 142 VSKNITSVLENLLKNYENSQLPTHGKGYPTV-VQTNILIRSMGPVSELDMDYSMDCYFRQ 200
++K+ + E LL+ ++ G G P + V ++ + S+ +SE+DMD++M Y R
Sbjct: 62 ITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRH 121
Query: 201 YWRDTRLSFLGPIR-SLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDI 259
YW+D RLSF S++ +++++IW PD +F + K S++H T N +LR+ G +
Sbjct: 122 YWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKV 181
Query: 260 LYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW-QNSQSVNFVPGMTLS 318
LYS+R+T+ A C M+ FP+D Q+C L + SYAY+ L+ W + + S+ ++LS
Sbjct: 182 LYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLS 241
Query: 319 QFDLISF-PYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIH 377
QF + F F G ++ L ++F L+RH +FL+Q Y P L+V+LSWVSFWI
Sbjct: 242 QFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWID 301
Query: 378 R 378
R
Sbjct: 302 R 302
Score = 39.9 bits (89), Expect = 0.022
Identities = 18/58 (31%), Positives = 33/58 (56%), Gaps = 1/58 (1%)
Query: 465 RQLLYCLAGDDRYRRQRQREAGSRGHINSVSH-IDRAARVLFPASFALLNLFYWMIYA 521
R ++ +R QR+ + S + +H ID+ +R++FPA++ L NL YW I++
Sbjct: 417 RMMVQLTLASERSSPQRKSQRSSYVSMRIDTHAIDKYSRIIFPAAYILFNLIYWSIFS 474
>AL353659-1|CAC36328.2| 473|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, rho 1 protein.
Length = 473
Score = 176 bits (428), Expect = 2e-43
Identities = 87/241 (36%), Positives = 142/241 (58%), Gaps = 4/241 (1%)
Query: 142 VSKNITSVLENLLKNYENSQLPTHGKGYPTV-VQTNILIRSMGPVSELDMDYSMDCYFRQ 200
++K+ + E LL+ ++ G G P + V ++ + S+ +SE+DMD++M Y R
Sbjct: 61 ITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRH 120
Query: 201 YWRDTRLSFLGPIR-SLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDI 259
YW+D RLSF S++ +++++IW PD +F + K S++H T N +LR+ G +
Sbjct: 121 YWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKV 180
Query: 260 LYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW-QNSQSVNFVPGMTLS 318
LYS+R+T+ A C M+ FP+D Q+C L + SYAY+ L+ W + + S+ ++LS
Sbjct: 181 LYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLS 240
Query: 319 QFDLISF-PYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIH 377
QF + F F G ++ L ++F L+RH +FL+Q Y P L+V+LSWVSFWI
Sbjct: 241 QFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWID 300
Query: 378 R 378
R
Sbjct: 301 R 301
Score = 39.9 bits (89), Expect = 0.022
Identities = 18/58 (31%), Positives = 33/58 (56%), Gaps = 1/58 (1%)
Query: 465 RQLLYCLAGDDRYRRQRQREAGSRGHINSVSH-IDRAARVLFPASFALLNLFYWMIYA 521
R ++ +R QR+ + S + +H ID+ +R++FPA++ L NL YW I++
Sbjct: 416 RMMVQLTLASERSSPQRKSQRSSYVSMRIDTHAIDKYSRIIFPAAYILFNLIYWSIFS 473
>AL353135-4|CAI16246.1| 473|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, rho 1 protein.
Length = 473
Score = 176 bits (428), Expect = 2e-43
Identities = 87/241 (36%), Positives = 142/241 (58%), Gaps = 4/241 (1%)
Query: 142 VSKNITSVLENLLKNYENSQLPTHGKGYPTV-VQTNILIRSMGPVSELDMDYSMDCYFRQ 200
++K+ + E LL+ ++ G G P + V ++ + S+ +SE+DMD++M Y R
Sbjct: 61 ITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRH 120
Query: 201 YWRDTRLSFLGPIR-SLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDI 259
YW+D RLSF S++ +++++IW PD +F + K S++H T N +LR+ G +
Sbjct: 121 YWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKV 180
Query: 260 LYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW-QNSQSVNFVPGMTLS 318
LYS+R+T+ A C M+ FP+D Q+C L + SYAY+ L+ W + + S+ ++LS
Sbjct: 181 LYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLS 240
Query: 319 QFDLISF-PYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIH 377
QF + F F G ++ L ++F L+RH +FL+Q Y P L+V+LSWVSFWI
Sbjct: 241 QFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWID 300
Query: 378 R 378
R
Sbjct: 301 R 301
Score = 39.9 bits (89), Expect = 0.022
Identities = 18/58 (31%), Positives = 33/58 (56%), Gaps = 1/58 (1%)
Query: 465 RQLLYCLAGDDRYRRQRQREAGSRGHINSVSH-IDRAARVLFPASFALLNLFYWMIYA 521
R ++ +R QR+ + S + +H ID+ +R++FPA++ L NL YW I++
Sbjct: 416 RMMVQLTLASERSSPQRKSQRSSYVSMRIDTHAIDKYSRIIFPAAYILFNLIYWSIFS 473
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 175 bits (426), Expect = 3e-43
Identities = 79/254 (31%), Positives = 144/254 (56%), Gaps = 5/254 (1%)
Query: 135 KRSINDAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSM 194
K N+AV + +L+ +L Y+ P G G P V+ +I + S+ +SE++MDY++
Sbjct: 51 KNCANEAV---VQKILDRVLSRYDVRLRPNFG-GAPVPVRISIYVTSIEQISEMNMDYTI 106
Query: 195 DCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRIS 254
+F Q W+D+RL++ +L+L +M E++W PD YF N K ++VH +TV N++ ++
Sbjct: 107 TMFFHQTWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLH 166
Query: 255 QHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW-QNSQSVNFVP 313
G + Y +RLT A C ++L FPMD+Q+C L++ SY Y+ + ++ W N +++
Sbjct: 167 PDGTVRYGIRLTTTAACSLDLHKFPMDKQACNLVVESYGYTVEDIILFWDDNGNAIHMTE 226
Query: 314 GMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVS 373
+ + QF + + G + L + F ++R +L+QVY P +L + SW+S
Sbjct: 227 ELHIPQFTFLGRTITSKEVYFYTGSYIRLILKFQVQREVNSYLVQVYWPTVLTTITSWIS 286
Query: 374 FWIHREVGSGEIVI 387
FW++ + + + I
Sbjct: 287 FWMNYDSSAARVTI 300
Score = 32.7 bits (71), Expect = 3.4
Identities = 11/29 (37%), Positives = 19/29 (65%)
Query: 494 VSHIDRAARVLFPASFALLNLFYWMIYAF 522
V +D+ +R LFP +F L N+ YW+ + +
Sbjct: 604 VPKVDKWSRFLFPLAFGLFNIVYWVYHMY 632
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 175 bits (426), Expect = 3e-43
Identities = 79/254 (31%), Positives = 144/254 (56%), Gaps = 5/254 (1%)
Query: 135 KRSINDAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSM 194
K N+AV + +L+ +L Y+ P G G P V+ +I + S+ +SE++MDY++
Sbjct: 51 KNCANEAV---VQKILDRVLSRYDVRLRPNFG-GAPVPVRISIYVTSIEQISEMNMDYTI 106
Query: 195 DCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRIS 254
+F Q W+D+RL++ +L+L +M E++W PD YF N K ++VH +TV N++ ++
Sbjct: 107 TMFFHQTWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLH 166
Query: 255 QHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW-QNSQSVNFVP 313
G + Y +RLT A C ++L FPMD+Q+C L++ SY Y+ + ++ W N +++
Sbjct: 167 PDGTVRYGIRLTTTAACSLDLHKFPMDKQACNLVVESYGYTVEDIILFWDDNGNAIHMTE 226
Query: 314 GMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVS 373
+ + QF + + G + L + F ++R +L+QVY P +L + SW+S
Sbjct: 227 ELHIPQFTFLGRTITSKEVYFYTGSYIRLILKFQVQREVNSYLVQVYWPTVLTTITSWIS 286
Query: 374 FWIHREVGSGEIVI 387
FW++ + + + I
Sbjct: 287 FWMNYDSSAARVTI 300
Score = 32.7 bits (71), Expect = 3.4
Identities = 11/29 (37%), Positives = 19/29 (65%)
Query: 494 VSHIDRAARVLFPASFALLNLFYWMIYAF 522
V +D+ +R LFP +F L N+ YW+ + +
Sbjct: 604 VPKVDKWSRFLFPLAFGLFNIVYWVYHMY 632
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 175 bits (426), Expect = 3e-43
Identities = 79/254 (31%), Positives = 144/254 (56%), Gaps = 5/254 (1%)
Query: 135 KRSINDAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSM 194
K N+AV + +L+ +L Y+ P G G P V+ +I + S+ +SE++MDY++
Sbjct: 51 KNCANEAV---VQKILDRVLSRYDVRLRPNFG-GAPVPVRISIYVTSIEQISEMNMDYTI 106
Query: 195 DCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRIS 254
+F Q W+D+RL++ +L+L +M E++W PD YF N K ++VH +TV N++ ++
Sbjct: 107 TMFFHQTWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLH 166
Query: 255 QHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW-QNSQSVNFVP 313
G + Y +RLT A C ++L FPMD+Q+C L++ SY Y+ + ++ W N +++
Sbjct: 167 PDGTVRYGIRLTTTAACSLDLHKFPMDKQACNLVVESYGYTVEDIILFWDDNGNAIHMTE 226
Query: 314 GMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVS 373
+ + QF + + G + L + F ++R +L+QVY P +L + SW+S
Sbjct: 227 ELHIPQFTFLGRTITSKEVYFYTGSYIRLILKFQVQREVNSYLVQVYWPTVLTTITSWIS 286
Query: 374 FWIHREVGSGEIVI 387
FW++ + + + I
Sbjct: 287 FWMNYDSSAARVTI 300
Score = 32.7 bits (71), Expect = 3.4
Identities = 11/29 (37%), Positives = 19/29 (65%)
Query: 494 VSHIDRAARVLFPASFALLNLFYWMIYAF 522
V +D+ +R LFP +F L N+ YW+ + +
Sbjct: 604 VPKVDKWSRFLFPLAFGLFNIVYWVYHMY 632
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 175 bits (426), Expect = 3e-43
Identities = 79/254 (31%), Positives = 144/254 (56%), Gaps = 5/254 (1%)
Query: 135 KRSINDAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSM 194
K N+AV + +L+ +L Y+ P G G P V+ +I + S+ +SE++MDY++
Sbjct: 46 KNCANEAV---VQKILDRVLSRYDVRLRPNFG-GAPVPVRISIYVTSIEQISEMNMDYTI 101
Query: 195 DCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRIS 254
+F Q W+D+RL++ +L+L +M E++W PD YF N K ++VH +TV N++ ++
Sbjct: 102 TMFFHQTWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLH 161
Query: 255 QHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW-QNSQSVNFVP 313
G + Y +RLT A C ++L FPMD+Q+C L++ SY Y+ + ++ W N +++
Sbjct: 162 PDGTVRYGIRLTTTAACSLDLHKFPMDKQACNLVVESYGYTVEDIILFWDDNGNAIHMTE 221
Query: 314 GMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVS 373
+ + QF + + G + L + F ++R +L+QVY P +L + SW+S
Sbjct: 222 ELHIPQFTFLGRTITSKEVYFYTGSYIRLILKFQVQREVNSYLVQVYWPTVLTTITSWIS 281
Query: 374 FWIHREVGSGEIVI 387
FW++ + + + I
Sbjct: 282 FWMNYDSSAARVTI 295
Score = 32.7 bits (71), Expect = 3.4
Identities = 11/29 (37%), Positives = 19/29 (65%)
Query: 494 VSHIDRAARVLFPASFALLNLFYWMIYAF 522
V +D+ +R LFP +F L N+ YW+ + +
Sbjct: 599 VPKVDKWSRFLFPLAFGLFNIVYWVYHMY 627
>U33267-1|AAB37750.1| 497|Homo sapiens glycine receptor beta
subunit protein.
Length = 497
Score = 173 bits (420), Expect = 2e-42
Identities = 91/260 (35%), Positives = 144/260 (55%), Gaps = 8/260 (3%)
Query: 132 KQNKRSINDAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMD 191
+Q+ + + + +++L LL +Y+ P KG P V NI I S G + E MD
Sbjct: 42 QQSAEDLARVPANSTSNILNRLLVSYDPRIRPNF-KGIPVDVVVNIFINSFGSIQETTMD 100
Query: 192 YSMDCYFRQYWRDTRLSFLGPIR---SLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPN 248
Y ++ + RQ W D RL R +L++ M + +W+PD +F N K + H +T N
Sbjct: 101 YRVNIFLRQKWNDPRLKLPSDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQEN 160
Query: 249 KLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQS 308
LL I + GD+L SMRL+I CP++L FPMD Q C + L S+ Y+ L + WQ+
Sbjct: 161 ILLFIFRDGDVLVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDP 220
Query: 309 VNFVPGMTLSQFDL--ISFPYRNFT-FTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCIL 365
V + + L QFD+ Y N T + + G ++ ++V F L+R G++++ VY P +L
Sbjct: 221 VQ-LEKIALPQFDIKKEDIEYGNCTKYYKGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLL 279
Query: 366 IVVLSWVSFWIHREVGSGEI 385
IVVLSW+SFWI+ + + +
Sbjct: 280 IVVLSWLSFWINPDASAARV 299
Score = 32.3 bits (70), Expect = 4.4
Identities = 13/28 (46%), Positives = 15/28 (53%)
Query: 493 SVSHIDRAARVLFPASFALLNLFYWMIY 520
+ ID AR LFP F N+ YW IY
Sbjct: 469 AAKRIDLYARALFPFCFLFFNVIYWSIY 496
>BC032635-1|AAH32635.1| 497|Homo sapiens glycine receptor, beta
protein.
Length = 497
Score = 173 bits (420), Expect = 2e-42
Identities = 91/260 (35%), Positives = 144/260 (55%), Gaps = 8/260 (3%)
Query: 132 KQNKRSINDAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMD 191
+Q+ + + + +++L LL +Y+ P KG P V NI I S G + E MD
Sbjct: 42 QQSAEDLARVPANSTSNILNRLLVSYDPRIRPNF-KGIPVDVVVNIFINSFGSIQETTMD 100
Query: 192 YSMDCYFRQYWRDTRLSFLGPIR---SLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPN 248
Y ++ + RQ W D RL R +L++ M + +W+PD +F N K + H +T N
Sbjct: 101 YRVNIFLRQKWNDPRLKLPSDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQEN 160
Query: 249 KLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQS 308
LL I + GD+L SMRL+I CP++L FPMD Q C + L S+ Y+ L + WQ+
Sbjct: 161 ILLFIFRDGDVLVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDP 220
Query: 309 VNFVPGMTLSQFDL--ISFPYRNFT-FTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCIL 365
V + + L QFD+ Y N T + + G ++ ++V F L+R G++++ VY P +L
Sbjct: 221 VQ-LEKIALPQFDIKKEDIEYGNCTKYYKGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLL 279
Query: 366 IVVLSWVSFWIHREVGSGEI 385
IVVLSW+SFWI+ + + +
Sbjct: 280 IVVLSWLSFWINPDASAARV 299
Score = 32.3 bits (70), Expect = 4.4
Identities = 13/28 (46%), Positives = 15/28 (53%)
Query: 493 SVSHIDRAARVLFPASFALLNLFYWMIY 520
+ ID AR LFP F N+ YW IY
Sbjct: 469 AAKRIDLYARALFPFCFLFFNVIYWSIY 496
>AF094755-1|AAC71034.1| 497|Homo sapiens glycine receptor beta
subunit precursor protein.
Length = 497
Score = 173 bits (420), Expect = 2e-42
Identities = 91/260 (35%), Positives = 144/260 (55%), Gaps = 8/260 (3%)
Query: 132 KQNKRSINDAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMD 191
+Q+ + + + +++L LL +Y+ P KG P V NI I S G + E MD
Sbjct: 42 QQSAEDLARVPANSTSNILNRLLVSYDPRIRPNF-KGIPVDVVVNIFINSFGSIQETTMD 100
Query: 192 YSMDCYFRQYWRDTRLSFLGPIR---SLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPN 248
Y ++ + RQ W D RL R +L++ M + +W+PD +F N K + H +T N
Sbjct: 101 YRVNIFLRQKWNDPRLKLPSDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQEN 160
Query: 249 KLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQS 308
LL I + GD+L SMRL+I CP++L FPMD Q C + L S+ Y+ L + WQ+
Sbjct: 161 ILLFIFRDGDVLVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDP 220
Query: 309 VNFVPGMTLSQFDL--ISFPYRNFT-FTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCIL 365
V + + L QFD+ Y N T + + G ++ ++V F L+R G++++ VY P +L
Sbjct: 221 VQ-LEKIALPQFDIKKEDIEYGNCTKYYKGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLL 279
Query: 366 IVVLSWVSFWIHREVGSGEI 385
IVVLSW+SFWI+ + + +
Sbjct: 280 IVVLSWLSFWINPDASAARV 299
Score = 32.3 bits (70), Expect = 4.4
Identities = 13/28 (46%), Positives = 15/28 (53%)
Query: 493 SVSHIDRAARVLFPASFALLNLFYWMIY 520
+ ID AR LFP F N+ YW IY
Sbjct: 469 AAKRIDLYARALFPFCFLFFNVIYWSIY 496
>AF094754-1|AAC71033.1| 497|Homo sapiens glycine receptor beta
subunit precursor protein.
Length = 497
Score = 173 bits (420), Expect = 2e-42
Identities = 91/260 (35%), Positives = 144/260 (55%), Gaps = 8/260 (3%)
Query: 132 KQNKRSINDAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMD 191
+Q+ + + + +++L LL +Y+ P KG P V NI I S G + E MD
Sbjct: 42 QQSAEDLARVPANSTSNILNRLLVSYDPRIRPNF-KGIPVDVVVNIFINSFGSIQETTMD 100
Query: 192 YSMDCYFRQYWRDTRLSFLGPIR---SLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPN 248
Y ++ + RQ W D RL R +L++ M + +W+PD +F N K + H +T N
Sbjct: 101 YRVNIFLRQKWNDPRLKLPSDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQEN 160
Query: 249 KLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQS 308
LL I + GD+L SMRL+I CP++L FPMD Q C + L S+ Y+ L + WQ+
Sbjct: 161 ILLFIFRDGDVLVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDP 220
Query: 309 VNFVPGMTLSQFDL--ISFPYRNFT-FTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCIL 365
V + + L QFD+ Y N T + + G ++ ++V F L+R G++++ VY P +L
Sbjct: 221 VQ-LEKIALPQFDIKKEDIEYGNCTKYYKGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLL 279
Query: 366 IVVLSWVSFWIHREVGSGEI 385
IVVLSW+SFWI+ + + +
Sbjct: 280 IVVLSWLSFWINPDASAARV 299
Score = 32.3 bits (70), Expect = 4.4
Identities = 13/28 (46%), Positives = 15/28 (53%)
Query: 493 SVSHIDRAARVLFPASFALLNLFYWMIY 520
+ ID AR LFP F N+ YW IY
Sbjct: 469 AAKRIDLYARALFPFCFLFFNVIYWSIY 496
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 169 bits (412), Expect = 2e-41
Identities = 84/228 (36%), Positives = 135/228 (59%), Gaps = 5/228 (2%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL 210
ENL Y P G G P + + I S+ +SE +MDY+ Y RQ W D RL F
Sbjct: 42 ENLTAGYNKFLRPNFG-GEPVQIALTLDIASISSISESNMDYTATIYLRQRWMDQRLVFE 100
Query: 211 GPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAK 270
G +S +L +++E +W PDTY K S++H +TV N+L+R+ +G +LY++R+T
Sbjct: 101 GN-KSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVA 159
Query: 271 CPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW-QNSQSVNFVPGMTLSQFDLISFPYRN 329
C M+L +PMD Q+C L L S+ Y + + W + + SV + + L+Q+ + + +
Sbjct: 160 CNMDLSKYPMDTQTCKLQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERY-FTL 218
Query: 330 FTFTRRE-GDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
T +++E G+++ L + F L+R+ YF+++ YVP +VVLSWVSFWI
Sbjct: 219 VTRSQQETGNYTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWI 266
Score = 35.9 bits (79), Expect = 0.36
Identities = 13/32 (40%), Positives = 21/32 (65%)
Query: 491 INSVSHIDRAARVLFPASFALLNLFYWMIYAF 522
I + S++D +++LFP F L N+FYW Y +
Sbjct: 408 IQNPSNVDHYSKLLFPLIFMLANVFYWAYYMY 439
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 169 bits (412), Expect = 2e-41
Identities = 84/228 (36%), Positives = 135/228 (59%), Gaps = 5/228 (2%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL 210
ENL Y P G G P + + I S+ +SE +MDY+ Y RQ W D RL F
Sbjct: 42 ENLTAGYNKFLRPNFG-GEPVQIALTLDIASISSISESNMDYTATIYLRQRWMDQRLVFE 100
Query: 211 GPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAK 270
G +S +L +++E +W PDTY K S++H +TV N+L+R+ +G +LY++R+T
Sbjct: 101 GN-KSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVA 159
Query: 271 CPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW-QNSQSVNFVPGMTLSQFDLISFPYRN 329
C M+L +PMD Q+C L L S+ Y + + W + + SV + + L+Q+ + + +
Sbjct: 160 CNMDLSKYPMDTQTCKLQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERY-FTL 218
Query: 330 FTFTRRE-GDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
T +++E G+++ L + F L+R+ YF+++ YVP +VVLSWVSFWI
Sbjct: 219 VTRSQQETGNYTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWI 266
Score = 35.9 bits (79), Expect = 0.36
Identities = 13/32 (40%), Positives = 21/32 (65%)
Query: 491 INSVSHIDRAARVLFPASFALLNLFYWMIYAF 522
I + S++D +++LFP F L N+FYW Y +
Sbjct: 408 IQNPSNVDHYSKLLFPLIFMLANVFYWAYYMY 439
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 169 bits (412), Expect = 2e-41
Identities = 84/228 (36%), Positives = 135/228 (59%), Gaps = 5/228 (2%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL 210
ENL Y P G G P + + I S+ +SE +MDY+ Y RQ W D RL F
Sbjct: 42 ENLTAGYNKFLRPNFG-GEPVQIALTLDIASISSISESNMDYTATIYLRQRWMDQRLVFE 100
Query: 211 GPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAK 270
G +S +L +++E +W PDTY K S++H +TV N+L+R+ +G +LY++R+T
Sbjct: 101 GN-KSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVA 159
Query: 271 CPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW-QNSQSVNFVPGMTLSQFDLISFPYRN 329
C M+L +PMD Q+C L L S+ Y + + W + + SV + + L+Q+ + + +
Sbjct: 160 CNMDLSKYPMDTQTCKLQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERY-FTL 218
Query: 330 FTFTRRE-GDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
T +++E G+++ L + F L+R+ YF+++ YVP +VVLSWVSFWI
Sbjct: 219 VTRSQQETGNYTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWI 266
Score = 35.9 bits (79), Expect = 0.36
Identities = 13/32 (40%), Positives = 21/32 (65%)
Query: 491 INSVSHIDRAARVLFPASFALLNLFYWMIYAF 522
I + S++D +++LFP F L N+FYW Y +
Sbjct: 408 IQNPSNVDHYSKLLFPLIFMLANVFYWAYYMY 439
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 169 bits (412), Expect = 2e-41
Identities = 84/228 (36%), Positives = 135/228 (59%), Gaps = 5/228 (2%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL 210
ENL Y P G G P + + I S+ +SE +MDY+ Y RQ W D RL F
Sbjct: 42 ENLTAGYNKFLRPNFG-GEPVQIALTLDIASISSISESNMDYTATIYLRQRWMDQRLVFE 100
Query: 211 GPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAK 270
G +S +L +++E +W PDTY K S++H +TV N+L+R+ +G +LY++R+T
Sbjct: 101 GN-KSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVA 159
Query: 271 CPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW-QNSQSVNFVPGMTLSQFDLISFPYRN 329
C M+L +PMD Q+C L L S+ Y + + W + + SV + + L+Q+ + + +
Sbjct: 160 CNMDLSKYPMDTQTCKLQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERY-FTL 218
Query: 330 FTFTRRE-GDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
T +++E G+++ L + F L+R+ YF+++ YVP +VVLSWVSFWI
Sbjct: 219 VTRSQQETGNYTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWI 266
Score = 35.9 bits (79), Expect = 0.36
Identities = 13/32 (40%), Positives = 21/32 (65%)
Query: 491 INSVSHIDRAARVLFPASFALLNLFYWMIYAF 522
I + S++D +++LFP F L N+FYW Y +
Sbjct: 408 IQNPSNVDHYSKLLFPLIFMLANVFYWAYYMY 439
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 169 bits (412), Expect = 2e-41
Identities = 84/228 (36%), Positives = 135/228 (59%), Gaps = 5/228 (2%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL 210
ENL Y P G G P + + I S+ +SE +MDY+ Y RQ W D RL F
Sbjct: 42 ENLTAGYNKFLRPNFG-GEPVQIALTLDIASISSISESNMDYTATIYLRQRWMDQRLVFE 100
Query: 211 GPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAK 270
G +S +L +++E +W PDTY K S++H +TV N+L+R+ +G +LY++R+T
Sbjct: 101 GN-KSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVA 159
Query: 271 CPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW-QNSQSVNFVPGMTLSQFDLISFPYRN 329
C M+L +PMD Q+C L L S+ Y + + W + + SV + + L+Q+ + + +
Sbjct: 160 CNMDLSKYPMDTQTCKLQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERY-FTL 218
Query: 330 FTFTRRE-GDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
T +++E G+++ L + F L+R+ YF+++ YVP +VVLSWVSFWI
Sbjct: 219 VTRSQQETGNYTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWI 266
Score = 35.9 bits (79), Expect = 0.36
Identities = 13/32 (40%), Positives = 21/32 (65%)
Query: 491 INSVSHIDRAARVLFPASFALLNLFYWMIYAF 522
I + S++D +++LFP F L N+FYW Y +
Sbjct: 408 IQNPSNVDHYSKLLFPLIFMLANVFYWAYYMY 439
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 169 bits (412), Expect = 2e-41
Identities = 84/228 (36%), Positives = 135/228 (59%), Gaps = 5/228 (2%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL 210
ENL Y P G G P + + I S+ +SE +MDY+ Y RQ W D RL F
Sbjct: 42 ENLTAGYNKFLRPNFG-GEPVQIALTLDIASISSISESNMDYTATIYLRQRWMDQRLVFE 100
Query: 211 GPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAK 270
G +S +L +++E +W PDTY K S++H +TV N+L+R+ +G +LY++R+T
Sbjct: 101 GN-KSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVA 159
Query: 271 CPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW-QNSQSVNFVPGMTLSQFDLISFPYRN 329
C M+L +PMD Q+C L L S+ Y + + W + + SV + + L+Q+ + + +
Sbjct: 160 CNMDLSKYPMDTQTCKLQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERY-FTL 218
Query: 330 FTFTRRE-GDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
T +++E G+++ L + F L+R+ YF+++ YVP +VVLSWVSFWI
Sbjct: 219 VTRSQQETGNYTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWI 266
Score = 35.9 bits (79), Expect = 0.36
Identities = 13/32 (40%), Positives = 21/32 (65%)
Query: 491 INSVSHIDRAARVLFPASFALLNLFYWMIYAF 522
I + S++D +++LFP F L N+FYW Y +
Sbjct: 408 IQNPSNVDHYSKLLFPLIFMLANVFYWAYYMY 439
>AF228447-1|AAF62508.1| 96|Homo sapiens gamma-aminobutyric acid
receptor alpha 5 subunit protein.
Length = 96
Score = 113 bits (272), Expect = 1e-24
Identities = 47/94 (50%), Positives = 68/94 (72%)
Query: 171 TVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPD 230
T V+T+I + S GPVS+ +M+Y++D +FRQ W+D RL F GP++ L L+ + +IW PD
Sbjct: 3 TQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPD 62
Query: 231 TYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
T+F+NGK S H +T PNKLLR+ G +LY+MR
Sbjct: 63 TFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMR 96
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 81.0 bits (191), Expect = 1e-14
Identities = 56/249 (22%), Positives = 119/249 (47%), Gaps = 14/249 (5%)
Query: 139 NDAVSKNITSVLENLLKN--YENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDC 196
N V+ ++++LL Y N P ++ + + + V+E + + +
Sbjct: 20 NCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQIMTTNV 79
Query: 197 YFRQYWRDTRLSFLGPIRSLSLSIKML--ERIWRPDTYFYNGKHSYVHTITVPNKLLRIS 254
+ +Q W D RL++ R ++I + +RIW PD YN +Y ++V L+ +
Sbjct: 80 WLKQEWTDYRLTW-NSSRYEGVNILRIPAKRIWLPDIVLYNNDGTY--EVSVYTNLI-VR 135
Query: 255 QHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQ--LVYQWQNSQSVNFV 312
+G +L+ K+ C +E++ FP D+Q+C L S+ Y + + +V + +F
Sbjct: 136 SNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMDDFT 195
Query: 313 PGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWV 372
P ++D+++ P R T ++ + + F +KR ++ I + +PC+L +L+ +
Sbjct: 196 PS---GEWDIVALPGRR-TVNPQDPSYVDVTYDFIIKRKPLFYTINLIIPCVLTTLLAIL 251
Query: 373 SFWIHREVG 381
F++ + G
Sbjct: 252 VFYLPSDCG 260
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 79.8 bits (188), Expect = 2e-14
Identities = 55/249 (22%), Positives = 115/249 (46%), Gaps = 13/249 (5%)
Query: 139 NDAVSKNITSVLENLLKN--YENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDC 196
N V+ ++++LL Y N P ++ + + + V+E + + +
Sbjct: 20 NCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQIMTTNV 79
Query: 197 YFRQYWRDTRLSFLGPIRSLSLSIKML--ERIWRPDTYFYNGKHSYVHTITVPNKLLRIS 254
+ +Q W D RL++ R ++I + +RIW PD YN N ++R
Sbjct: 80 WLKQEWTDYRLTW-NSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNLIVR-- 136
Query: 255 QHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQ--LVYQWQNSQSVNFV 312
+G +L+ K+ C +E++ FP D+Q+C L S+ Y + + +V + +F
Sbjct: 137 SNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMDDFT 196
Query: 313 PGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWV 372
P ++D+++ P R T ++ + + F +KR ++ I + +PC+L +L+ +
Sbjct: 197 PS---GEWDIVALPGRR-TVNPQDPSYVDVTYDFIIKRKPLFYTINLIIPCVLTTLLAIL 252
Query: 373 SFWIHREVG 381
F++ + G
Sbjct: 253 VFYLPSDCG 261
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 79.8 bits (188), Expect = 2e-14
Identities = 55/249 (22%), Positives = 115/249 (46%), Gaps = 13/249 (5%)
Query: 139 NDAVSKNITSVLENLLKN--YENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDC 196
N V+ ++++LL Y N P ++ + + + V+E + + +
Sbjct: 20 NCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQIMTTNV 79
Query: 197 YFRQYWRDTRLSFLGPIRSLSLSIKML--ERIWRPDTYFYNGKHSYVHTITVPNKLLRIS 254
+ +Q W D RL++ R ++I + +RIW PD YN N ++R
Sbjct: 80 WLKQEWTDYRLTW-NSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNLIVR-- 136
Query: 255 QHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQ--LVYQWQNSQSVNFV 312
+G +L+ K+ C +E++ FP D+Q+C L S+ Y + + +V + +F
Sbjct: 137 SNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMDDFT 196
Query: 313 PGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWV 372
P ++D+++ P R T ++ + + F +KR ++ I + +PC+L +L+ +
Sbjct: 197 PS---GEWDIVALPGRR-TVNPQDPSYVDVTYDFIIKRKPLFYTINLIIPCVLTTLLAIL 252
Query: 373 SFWIHREVG 381
F++ + G
Sbjct: 253 VFYLPSDCG 261
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 79.8 bits (188), Expect = 2e-14
Identities = 55/249 (22%), Positives = 115/249 (46%), Gaps = 13/249 (5%)
Query: 139 NDAVSKNITSVLENLLKN--YENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDC 196
N V+ ++++LL Y N P ++ + + + V+E + + +
Sbjct: 20 NCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQIMTTNV 79
Query: 197 YFRQYWRDTRLSFLGPIRSLSLSIKML--ERIWRPDTYFYNGKHSYVHTITVPNKLLRIS 254
+ +Q W D RL++ R ++I + +RIW PD YN N ++R
Sbjct: 80 WLKQEWTDYRLTW-NSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNLIVR-- 136
Query: 255 QHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQ--LVYQWQNSQSVNFV 312
+G +L+ K+ C +E++ FP D+Q+C L S+ Y + + +V + +F
Sbjct: 137 SNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMDDFT 196
Query: 313 PGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWV 372
P ++D+++ P R T ++ + + F +KR ++ I + +PC+L +L+ +
Sbjct: 197 PS---GEWDIVALPGRR-TVNPQDPSYVDVTYDFIIKRKPLFYTINLIIPCVLTTLLAIL 252
Query: 373 SFWIHREVG 381
F++ + G
Sbjct: 253 VFYLPSDCG 261
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 79.8 bits (188), Expect = 2e-14
Identities = 55/249 (22%), Positives = 115/249 (46%), Gaps = 13/249 (5%)
Query: 139 NDAVSKNITSVLENLLKN--YENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDC 196
N V+ ++++LL Y N P ++ + + + V+E + + +
Sbjct: 20 NCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQIMTTNV 79
Query: 197 YFRQYWRDTRLSFLGPIRSLSLSIKML--ERIWRPDTYFYNGKHSYVHTITVPNKLLRIS 254
+ +Q W D RL++ R ++I + +RIW PD YN N ++R
Sbjct: 80 WLKQEWTDYRLTW-NSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNLIVR-- 136
Query: 255 QHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQ--LVYQWQNSQSVNFV 312
+G +L+ K+ C +E++ FP D+Q+C L S+ Y + + +V + +F
Sbjct: 137 SNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMDDFT 196
Query: 313 PGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWV 372
P ++D+++ P R T ++ + + F +KR ++ I + +PC+L +L+ +
Sbjct: 197 PS---GEWDIVALPGRR-TVNPQDPSYVDVTYDFIIKRKPLFYTINLIIPCVLTTLLAIL 252
Query: 373 SFWIHREVG 381
F++ + G
Sbjct: 253 VFYLPSDCG 261
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 79.8 bits (188), Expect = 2e-14
Identities = 55/249 (22%), Positives = 115/249 (46%), Gaps = 13/249 (5%)
Query: 139 NDAVSKNITSVLENLLKN--YENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDC 196
N V+ ++++LL Y N P ++ + + + V+E + + +
Sbjct: 20 NCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQIMTTNV 79
Query: 197 YFRQYWRDTRLSFLGPIRSLSLSIKML--ERIWRPDTYFYNGKHSYVHTITVPNKLLRIS 254
+ +Q W D RL++ R ++I + +RIW PD YN N ++R
Sbjct: 80 WLKQEWTDYRLTW-NSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNLIVR-- 136
Query: 255 QHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQ--LVYQWQNSQSVNFV 312
+G +L+ K+ C +E++ FP D+Q+C L S+ Y + + +V + +F
Sbjct: 137 SNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMDDFT 196
Query: 313 PGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWV 372
P ++D+++ P R T ++ + + F +KR ++ I + +PC+L +L+ +
Sbjct: 197 PS---GEWDIVALPGRR-TVNPQDPSYVDVTYDFIIKRKPLFYTINLIIPCVLTTLLAIL 252
Query: 373 SFWIHREVG 381
F++ + G
Sbjct: 253 VFYLPSDCG 261
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 79.8 bits (188), Expect = 2e-14
Identities = 55/249 (22%), Positives = 115/249 (46%), Gaps = 13/249 (5%)
Query: 139 NDAVSKNITSVLENLLKN--YENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDC 196
N V+ ++++LL Y N P ++ + + + V+E + + +
Sbjct: 20 NCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQIMTTNV 79
Query: 197 YFRQYWRDTRLSFLGPIRSLSLSIKML--ERIWRPDTYFYNGKHSYVHTITVPNKLLRIS 254
+ +Q W D RL++ R ++I + +RIW PD YN N ++R
Sbjct: 80 WLKQEWTDYRLTW-NSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNLIVR-- 136
Query: 255 QHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQ--LVYQWQNSQSVNFV 312
+G +L+ K+ C +E++ FP D+Q+C L S+ Y + + +V + +F
Sbjct: 137 SNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMDDFT 196
Query: 313 PGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWV 372
P ++D+++ P R T ++ + + F +KR ++ I + +PC+L +L+ +
Sbjct: 197 PS---GEWDIVALPGRR-TVNPQDPSYVDVTYDFIIKRKPLFYTINLIIPCVLTTLLAIL 252
Query: 373 SFWIHREVG 381
F++ + G
Sbjct: 253 VFYLPSDCG 261
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 78.2 bits (184), Expect = 7e-14
Identities = 49/213 (23%), Positives = 103/213 (48%), Gaps = 11/213 (5%)
Query: 173 VQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKML--ERIWRPD 230
++ + + + V+E D + + + +Q W D RL++ R ++I + +RIW PD
Sbjct: 9 IKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTW-NSSRYEGVNILRIPAKRIWLPD 67
Query: 231 TYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILG 290
YN N ++R +G +L+ K+ C +E++ FP D+Q+C L
Sbjct: 68 IVLYNNADGTYEVSVYTNLIVR--SNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFR 125
Query: 291 SYAYSNQQ--LVYQWQNSQSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNL 348
S+ Y + + +V + +F P ++D+++ P R T ++ + + F +
Sbjct: 126 SWTYDHTEIDMVLMTPTASMDDFTPS---GEWDIVALPGRR-TVNPQDPSYVDVTYDFII 181
Query: 349 KRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
KR ++ I + +PC+L +L+ + F++ + G
Sbjct: 182 KRKPLFYTINLIIPCVLTTLLAILVFYLPSDCG 214
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 73.3 bits (172), Expect = 2e-12
Identities = 52/234 (22%), Positives = 101/234 (43%), Gaps = 8/234 (3%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL 210
+ L+KNY + P P V ++ + + V E + + + + + W D L +
Sbjct: 8 KELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWN 67
Query: 211 GPIRSLSLSIKMLE-RIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKA 269
+++ + +IW+PD YN N L+ S H Y K+
Sbjct: 68 VSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQ--YLPPGIFKS 125
Query: 270 KCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRN 329
C +++R FP D Q C L GS++Y L Q Q + ++P ++DL+ P +
Sbjct: 126 SCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPN---GEWDLVGIPGKR 182
Query: 330 FT--FTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ + + + + ++R T Y+ + + +PC+LI L+ + F + + G
Sbjct: 183 SERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSG 236
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 73.3 bits (172), Expect = 2e-12
Identities = 52/234 (22%), Positives = 101/234 (43%), Gaps = 8/234 (3%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL 210
+ L+KNY + P P V ++ + + V E + + + + + W D L +
Sbjct: 31 KELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWN 90
Query: 211 GPIRSLSLSIKMLE-RIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKA 269
+++ + +IW+PD YN N L+ S H Y K+
Sbjct: 91 VSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQ--YLPPGIFKS 148
Query: 270 KCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRN 329
C +++R FP D Q C L GS++Y L Q Q + ++P ++DL+ P +
Sbjct: 149 SCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPN---GEWDLVGIPGKR 205
Query: 330 FT--FTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ + + + + ++R T Y+ + + +PC+LI L+ + F + + G
Sbjct: 206 SERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSG 259
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 73.3 bits (172), Expect = 2e-12
Identities = 52/234 (22%), Positives = 101/234 (43%), Gaps = 8/234 (3%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL 210
+ L+KNY + P P V ++ + + V E + + + + + W D L +
Sbjct: 31 KELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWN 90
Query: 211 GPIRSLSLSIKMLE-RIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKA 269
+++ + +IW+PD YN N L+ S H Y K+
Sbjct: 91 VSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQ--YLPPGIFKS 148
Query: 270 KCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRN 329
C +++R FP D Q C L GS++Y L Q Q + ++P ++DL+ P +
Sbjct: 149 SCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPN---GEWDLVGIPGKR 205
Query: 330 FT--FTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ + + + + ++R T Y+ + + +PC+LI L+ + F + + G
Sbjct: 206 SERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSG 259
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 73.3 bits (172), Expect = 2e-12
Identities = 52/234 (22%), Positives = 101/234 (43%), Gaps = 8/234 (3%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL 210
+ L+KNY + P P V ++ + + V E + + + + + W D L +
Sbjct: 31 KELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWN 90
Query: 211 GPIRSLSLSIKMLE-RIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKA 269
+++ + +IW+PD YN N L+ S H Y K+
Sbjct: 91 VSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQ--YLPPGIFKS 148
Query: 270 KCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRN 329
C +++R FP D Q C L GS++Y L Q Q + ++P ++DL+ P +
Sbjct: 149 SCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPN---GEWDLVGIPGKR 205
Query: 330 FT--FTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ + + + + ++R T Y+ + + +PC+LI L+ + F + + G
Sbjct: 206 SERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSG 259
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 73.3 bits (172), Expect = 2e-12
Identities = 52/234 (22%), Positives = 101/234 (43%), Gaps = 8/234 (3%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL 210
+ L+KNY + P P V ++ + + V E + + + + + W D L +
Sbjct: 31 KELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWN 90
Query: 211 GPIRSLSLSIKMLE-RIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKA 269
+++ + +IW+PD YN N L+ S H Y K+
Sbjct: 91 VSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQ--YLPPGIFKS 148
Query: 270 KCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRN 329
C +++R FP D Q C L GS++Y L Q Q + ++P ++DL+ P +
Sbjct: 149 SCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPN---GEWDLVGIPGKR 205
Query: 330 FT--FTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ + + + + ++R T Y+ + + +PC+LI L+ + F + + G
Sbjct: 206 SERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSG 259
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 72.5 bits (170), Expect = 3e-12
Identities = 52/237 (21%), Positives = 104/237 (43%), Gaps = 8/237 (3%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+ L +Y P P V + I + V E++ + + R W D +L
Sbjct: 37 LFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKLR 96
Query: 209 FLGPIRSLSLSIKML--ERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLT 266
+ P+ + + ++IW+PD YN LL+ + G I ++
Sbjct: 97 W-DPMEYDGIETLRVPADKIWKPDIVLYNNAVGDFQVEGKTKALLKYN--GMITWTPPAI 153
Query: 267 IKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLI-SF 325
K+ CPM++ FP D Q+C L GS+ Y ++ S+ V+ S++++I +
Sbjct: 154 FKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSK-VDMNDFWENSEWEIIDAS 212
Query: 326 PYR-NFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y+ + + E ++ + SF ++R ++ I + +PC+ I L+ + F++ + G
Sbjct: 213 GYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCG 269
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 72.5 bits (170), Expect = 3e-12
Identities = 52/237 (21%), Positives = 104/237 (43%), Gaps = 8/237 (3%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+ L +Y P P V + I + V E++ + + R W D +L
Sbjct: 37 LFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKLR 96
Query: 209 FLGPIRSLSLSIKML--ERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLT 266
+ P+ + + ++IW+PD YN LL+ + G I ++
Sbjct: 97 W-DPMEYDGIETLRVPADKIWKPDIVLYNNAVGDFQVEGKTKALLKYN--GMITWTPPAI 153
Query: 267 IKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLI-SF 325
K+ CPM++ FP D Q+C L GS+ Y ++ S+ V+ S++++I +
Sbjct: 154 FKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSK-VDMNDFWENSEWEIIDAS 212
Query: 326 PYR-NFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y+ + + E ++ + SF ++R ++ I + +PC+ I L+ + F++ + G
Sbjct: 213 GYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCG 269
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 72.5 bits (170), Expect = 3e-12
Identities = 52/234 (22%), Positives = 101/234 (43%), Gaps = 8/234 (3%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL 210
+ L+KNY + P P V ++ + + V E + + + + + W D L +
Sbjct: 31 KELVKNYNPLERPVANDSQPLTVYFSLNLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWN 90
Query: 211 GPIRSLSLSIKMLE-RIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKA 269
+++ + +IW+PD YN N L+ S H Y K+
Sbjct: 91 VSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGHCQ--YLPPGIFKS 148
Query: 270 KCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRN 329
C +++R FP D Q C L GS++Y L Q Q + ++P ++DL+ P +
Sbjct: 149 SCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPN---GEWDLVGIPGKR 205
Query: 330 FT--FTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ + + + + ++R T Y+ + + +PC+LI L+ + F + + G
Sbjct: 206 SERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSG 259
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 72.5 bits (170), Expect = 3e-12
Identities = 52/237 (21%), Positives = 104/237 (43%), Gaps = 8/237 (3%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+ L +Y P P V + I + V E++ + + R W D +L
Sbjct: 37 LFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKLR 96
Query: 209 FLGPIRSLSLSIKML--ERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLT 266
+ P+ + + ++IW+PD YN LL+ + G I ++
Sbjct: 97 W-DPMEYDGIETLRVPADKIWKPDIVLYNNAVGDFQVEGKTKALLKYN--GMITWTPPAI 153
Query: 267 IKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLI-SF 325
K+ CPM++ FP D Q+C L GS+ Y ++ S+ V+ S++++I +
Sbjct: 154 FKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSK-VDMNDFWENSEWEIIDAS 212
Query: 326 PYR-NFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y+ + + E ++ + SF ++R ++ I + +PC+ I L+ + F++ + G
Sbjct: 213 GYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCG 269
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 72.5 bits (170), Expect = 3e-12
Identities = 52/234 (22%), Positives = 101/234 (43%), Gaps = 8/234 (3%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL 210
+ L+KNY + P P V ++ + + V E + + + + + W D L +
Sbjct: 31 KELVKNYNPLERPVANDSQPLTVYFSLNLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWN 90
Query: 211 GPIRSLSLSIKMLE-RIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKA 269
+++ + +IW+PD YN N L+ S H Y K+
Sbjct: 91 VSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGHCQ--YLPPGIFKS 148
Query: 270 KCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRN 329
C +++R FP D Q C L GS++Y L Q Q + ++P ++DL+ P +
Sbjct: 149 SCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPN---GEWDLVGIPGKR 205
Query: 330 FT--FTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ + + + + ++R T Y+ + + +PC+LI L+ + F + + G
Sbjct: 206 SERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSG 259
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 72.5 bits (170), Expect = 3e-12
Identities = 52/237 (21%), Positives = 104/237 (43%), Gaps = 8/237 (3%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+ L +Y P P V + I + V E++ + + R W D +L
Sbjct: 37 LFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKLR 96
Query: 209 FLGPIRSLSLSIKML--ERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLT 266
+ P+ + + ++IW+PD YN LL+ + G I ++
Sbjct: 97 W-DPMEYDGIETLRVPADKIWKPDIVLYNNAVGDFQVEGKTKALLKYN--GMITWTPPAI 153
Query: 267 IKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLI-SF 325
K+ CPM++ FP D Q+C L GS+ Y ++ S+ V+ S++++I +
Sbjct: 154 FKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSK-VDMNDFWENSEWEIIDAS 212
Query: 326 PYR-NFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y+ + + E ++ + SF ++R ++ I + +PC+ I L+ + F++ + G
Sbjct: 213 GYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCG 269
>AC131948-1|AAY40916.1| 74|Homo sapiens unknown protein.
Length = 74
Score = 71.7 bits (168), Expect = 6e-12
Identities = 33/74 (44%), Positives = 48/74 (64%), Gaps = 1/74 (1%)
Query: 191 DYSMDCYFRQYWRDTRLSFLG-PIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNK 249
DY ++ + RQ W D RL++ P SL L ML+ IW+PD +F N K + H +T NK
Sbjct: 1 DYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNK 60
Query: 250 LLRISQHGDILYSM 263
LLRI ++G++LYS+
Sbjct: 61 LLRIFKNGNVLYSI 74
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 70.5 bits (165), Expect = 1e-11
Identities = 60/275 (21%), Positives = 121/275 (44%), Gaps = 12/275 (4%)
Query: 117 NYANSSFEQTDVFTWKQNKRSINDAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTN 176
N+++S ++ R+ A K + +L ++Y N+ P V
Sbjct: 2 NWSHSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQ 61
Query: 177 ILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKM-LERIWRPDTYFYN 235
I + + + E + + + RQ W D L++ SI++ + +WRPD YN
Sbjct: 62 ITLSQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYN 121
Query: 236 GKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYS 295
N +LR G I + K+ C +++ FP D Q C L GS+ Y+
Sbjct: 122 KADDESSEPVNTNVVLRYD--GLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYN 179
Query: 296 NQQL-VYQWQNSQSVN-FVPGMTLSQFDLISFP-YRN-FTFTRREGDFSVLQVSFNLKRH 351
Q+ ++ +S ++ F+ + ++++ P +N ++ + + + LKR
Sbjct: 180 GNQVDIFNALDSGDLSDFIEDV---EWEVHGMPAVKNVISYGCCSEPYPDVTFTLLLKRR 236
Query: 352 TGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIV 386
+ ++++ + +PC+LI L+ +SF++ SGE V
Sbjct: 237 SSFYIVNLLIPCVLISFLAPLSFYL--PAASGEKV 269
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 70.5 bits (165), Expect = 1e-11
Identities = 60/275 (21%), Positives = 121/275 (44%), Gaps = 12/275 (4%)
Query: 117 NYANSSFEQTDVFTWKQNKRSINDAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTN 176
N+++S ++ R+ A K + +L ++Y N+ P V
Sbjct: 2 NWSHSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQ 61
Query: 177 ILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKM-LERIWRPDTYFYN 235
I + + + E + + + RQ W D L++ SI++ + +WRPD YN
Sbjct: 62 ITLSQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYN 121
Query: 236 GKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYS 295
N +LR G I + K+ C +++ FP D Q C L GS+ Y+
Sbjct: 122 KADDESSEPVNTNVVLRYD--GLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYN 179
Query: 296 NQQL-VYQWQNSQSVN-FVPGMTLSQFDLISFP-YRN-FTFTRREGDFSVLQVSFNLKRH 351
Q+ ++ +S ++ F+ + ++++ P +N ++ + + + LKR
Sbjct: 180 GNQVDIFNALDSGDLSDFIEDV---EWEVHGMPAVKNVISYGCCSEPYPDVTFTLLLKRR 236
Query: 352 TGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIV 386
+ ++++ + +PC+LI L+ +SF++ SGE V
Sbjct: 237 SSFYIVNLLIPCVLISFLAPLSFYL--PAASGEKV 269
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 70.5 bits (165), Expect = 1e-11
Identities = 60/275 (21%), Positives = 121/275 (44%), Gaps = 12/275 (4%)
Query: 117 NYANSSFEQTDVFTWKQNKRSINDAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTN 176
N+++S ++ R+ A K + +L ++Y N+ P V
Sbjct: 2 NWSHSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQ 61
Query: 177 ILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKM-LERIWRPDTYFYN 235
I + + + E + + + RQ W D L++ SI++ + +WRPD YN
Sbjct: 62 ITLSQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYN 121
Query: 236 GKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYS 295
N +LR G I + K+ C +++ FP D Q C L GS+ Y+
Sbjct: 122 KADDESSEPVNTNVVLRYD--GLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYN 179
Query: 296 NQQL-VYQWQNSQSVN-FVPGMTLSQFDLISFP-YRN-FTFTRREGDFSVLQVSFNLKRH 351
Q+ ++ +S ++ F+ + ++++ P +N ++ + + + LKR
Sbjct: 180 GNQVDIFNALDSGDLSDFIEDV---EWEVHGMPAVKNVISYGCCSEPYPDVTFTLLLKRR 236
Query: 352 TGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIV 386
+ ++++ + +PC+LI L+ +SF++ SGE V
Sbjct: 237 SSFYIVNLLIPCVLISFLAPLSFYL--PAASGEKV 269
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 70.5 bits (165), Expect = 1e-11
Identities = 60/275 (21%), Positives = 121/275 (44%), Gaps = 12/275 (4%)
Query: 117 NYANSSFEQTDVFTWKQNKRSINDAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTN 176
N+++S ++ R+ A K + +L ++Y N+ P V
Sbjct: 2 NWSHSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQ 61
Query: 177 ILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKM-LERIWRPDTYFYN 235
I + + + E + + + RQ W D L++ SI++ + +WRPD YN
Sbjct: 62 ITLSQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYN 121
Query: 236 GKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYS 295
N +LR G I + K+ C +++ FP D Q C L GS+ Y+
Sbjct: 122 KADDESSEPVNTNVVLRYD--GLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYN 179
Query: 296 NQQL-VYQWQNSQSVN-FVPGMTLSQFDLISFP-YRN-FTFTRREGDFSVLQVSFNLKRH 351
Q+ ++ +S ++ F+ + ++++ P +N ++ + + + LKR
Sbjct: 180 GNQVDIFNALDSGDLSDFIEDV---EWEVHGMPAVKNVISYGCCSEPYPDVTFTLLLKRR 236
Query: 352 TGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIV 386
+ ++++ + +PC+LI L+ +SF++ SGE V
Sbjct: 237 SSFYIVNLLIPCVLISFLAPLSFYL--PAASGEKV 269
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 70.5 bits (165), Expect = 1e-11
Identities = 60/275 (21%), Positives = 121/275 (44%), Gaps = 12/275 (4%)
Query: 117 NYANSSFEQTDVFTWKQNKRSINDAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTN 176
N+++S ++ R+ A K + +L ++Y N+ P V
Sbjct: 2 NWSHSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQ 61
Query: 177 ILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKM-LERIWRPDTYFYN 235
I + + + E + + + RQ W D L++ SI++ + +WRPD YN
Sbjct: 62 ITLSQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYN 121
Query: 236 GKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYS 295
N +LR G I + K+ C +++ FP D Q C L GS+ Y+
Sbjct: 122 KADDESSEPVNTNVVLRYD--GLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYN 179
Query: 296 NQQL-VYQWQNSQSVN-FVPGMTLSQFDLISFP-YRN-FTFTRREGDFSVLQVSFNLKRH 351
Q+ ++ +S ++ F+ + ++++ P +N ++ + + + LKR
Sbjct: 180 GNQVDIFNALDSGDLSDFIEDV---EWEVHGMPAVKNVISYGCCSEPYPDVTFTLLLKRR 236
Query: 352 TGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIV 386
+ ++++ + +PC+LI L+ +SF++ SGE V
Sbjct: 237 SSFYIVNLLIPCVLISFLAPLSFYL--PAASGEKV 269
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 70.1 bits (164), Expect = 2e-11
Identities = 49/221 (22%), Positives = 100/221 (45%), Gaps = 10/221 (4%)
Query: 164 THGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKML 223
T+G TV Q + + + V E + + + + Q W D RL++ +++
Sbjct: 50 TNGSELVTV-QLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLP 108
Query: 224 ER-IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDR 282
+ IW PD YN N + +S G I + K+ C +E+++FP D+
Sbjct: 109 SKHIWLPDVVLYNNADGMYEVSFYSNAV--VSYDGSIFWLPPAIYKSACKIEVKHFPFDQ 166
Query: 283 QSCPLILGSYAYSNQQ--LVYQWQNSQSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFS 340
Q+C + S+ Y + LV + + + +F P ++D+++ P R + +
Sbjct: 167 QNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPS---GEWDIVALPGRR-NENPDDSTYV 222
Query: 341 VLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ F ++R ++ I + +PC+LI L+ + F++ + G
Sbjct: 223 DITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSDCG 263
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 70.1 bits (164), Expect = 2e-11
Identities = 49/221 (22%), Positives = 100/221 (45%), Gaps = 10/221 (4%)
Query: 164 THGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKML 223
T+G TV Q + + + V E + + + + Q W D RL++ +++
Sbjct: 50 TNGSELVTV-QLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLP 108
Query: 224 ER-IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDR 282
+ IW PD YN N + +S G I + K+ C +E+++FP D+
Sbjct: 109 SKHIWLPDVVLYNNADGMYEVSFYSNAV--VSYDGSIFWLPPAIYKSACKIEVKHFPFDQ 166
Query: 283 QSCPLILGSYAYSNQQ--LVYQWQNSQSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFS 340
Q+C + S+ Y + LV + + + +F P ++D+++ P R + +
Sbjct: 167 QNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPS---GEWDIVALPGRR-NENPDDSTYV 222
Query: 341 VLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ F ++R ++ I + +PC+LI L+ + F++ + G
Sbjct: 223 DITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSDCG 263
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 70.1 bits (164), Expect = 2e-11
Identities = 49/221 (22%), Positives = 100/221 (45%), Gaps = 10/221 (4%)
Query: 164 THGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKML 223
T+G TV Q + + + V E + + + + Q W D RL++ +++
Sbjct: 50 TNGSELVTV-QLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLP 108
Query: 224 ER-IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDR 282
+ IW PD YN N + +S G I + K+ C +E+++FP D+
Sbjct: 109 SKHIWLPDVVLYNNADGMYEVSFYSNAV--VSYDGSIFWLPPAIYKSACKIEVKHFPFDQ 166
Query: 283 QSCPLILGSYAYSNQQ--LVYQWQNSQSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFS 340
Q+C + S+ Y + LV + + + +F P ++D+++ P R + +
Sbjct: 167 QNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPS---GEWDIVALPGRR-NENPDDSTYV 222
Query: 341 VLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ F ++R ++ I + +PC+LI L+ + F++ + G
Sbjct: 223 DITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSDCG 263
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 70.1 bits (164), Expect = 2e-11
Identities = 49/221 (22%), Positives = 100/221 (45%), Gaps = 10/221 (4%)
Query: 164 THGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKML 223
T+G TV Q + + + V E + + + + Q W D RL++ +++
Sbjct: 50 TNGSELVTV-QLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLP 108
Query: 224 ER-IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDR 282
+ IW PD YN N + +S G I + K+ C +E+++FP D+
Sbjct: 109 SKHIWLPDVVLYNNADGMYEVSFYSNAV--VSYDGSIFWLPPAIYKSACKIEVKHFPFDQ 166
Query: 283 QSCPLILGSYAYSNQQ--LVYQWQNSQSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFS 340
Q+C + S+ Y + LV + + + +F P ++D+++ P R + +
Sbjct: 167 QNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPS---GEWDIVALPGRR-NENPDDSTYV 222
Query: 341 VLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ F ++R ++ I + +PC+LI L+ + F++ + G
Sbjct: 223 DITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSDCG 263
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 70.1 bits (164), Expect = 2e-11
Identities = 49/221 (22%), Positives = 100/221 (45%), Gaps = 10/221 (4%)
Query: 164 THGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKML 223
T+G TV Q + + + V E + + + + Q W D RL++ +++
Sbjct: 50 TNGSELVTV-QLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLP 108
Query: 224 ER-IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDR 282
+ IW PD YN N + +S G I + K+ C +E+++FP D+
Sbjct: 109 SKHIWLPDVVLYNNADGMYEVSFYSNAV--VSYDGSIFWLPPAIYKSACKIEVKHFPFDQ 166
Query: 283 QSCPLILGSYAYSNQQ--LVYQWQNSQSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFS 340
Q+C + S+ Y + LV + + + +F P ++D+++ P R + +
Sbjct: 167 QNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPS---GEWDIVALPGRR-NENPDDSTYV 222
Query: 341 VLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ F ++R ++ I + +PC+LI L+ + F++ + G
Sbjct: 223 DITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSDCG 263
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 70.1 bits (164), Expect = 2e-11
Identities = 49/221 (22%), Positives = 100/221 (45%), Gaps = 10/221 (4%)
Query: 164 THGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKML 223
T+G TV Q + + + V E + + + + Q W D RL++ +++
Sbjct: 50 TNGSELVTV-QLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLP 108
Query: 224 ER-IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDR 282
+ IW PD YN N + +S G I + K+ C +E+++FP D+
Sbjct: 109 SKHIWLPDVVLYNNADGMYEVSFYSNAV--VSYDGSIFWLPPAIYKSACKIEVKHFPFDQ 166
Query: 283 QSCPLILGSYAYSNQQ--LVYQWQNSQSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFS 340
Q+C + S+ Y + LV + + + +F P ++D+++ P R + +
Sbjct: 167 QNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPS---GEWDIVALPGRR-NENPDDSTYV 222
Query: 341 VLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ F ++R ++ I + +PC+LI L+ + F++ + G
Sbjct: 223 DITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSDCG 263
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 70.1 bits (164), Expect = 2e-11
Identities = 49/221 (22%), Positives = 100/221 (45%), Gaps = 10/221 (4%)
Query: 164 THGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKML 223
T+G TV Q + + + V E + + + + Q W D RL++ +++
Sbjct: 50 TNGSELVTV-QLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLP 108
Query: 224 ER-IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDR 282
+ IW PD YN N + +S G I + K+ C +E+++FP D+
Sbjct: 109 SKHIWLPDVVLYNNADGMYEVSFYSNAV--VSYDGSIFWLPPAIYKSACKIEVKHFPFDQ 166
Query: 283 QSCPLILGSYAYSNQQ--LVYQWQNSQSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFS 340
Q+C + S+ Y + LV + + + +F P ++D+++ P R + +
Sbjct: 167 QNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPS---GEWDIVALPGRR-NENPDDSTYV 222
Query: 341 VLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ F ++R ++ I + +PC+LI L+ + F++ + G
Sbjct: 223 DITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSDCG 263
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 70.1 bits (164), Expect = 2e-11
Identities = 49/221 (22%), Positives = 100/221 (45%), Gaps = 10/221 (4%)
Query: 164 THGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKML 223
T+G TV Q + + + V E + + + + Q W D RL++ +++
Sbjct: 50 TNGSELVTV-QLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLP 108
Query: 224 ER-IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDR 282
+ IW PD YN N + +S G I + K+ C +E+++FP D+
Sbjct: 109 SKHIWLPDVVLYNNADGMYEVSFYSNAV--VSYDGSIFWLPPAIYKSACKIEVKHFPFDQ 166
Query: 283 QSCPLILGSYAYSNQQ--LVYQWQNSQSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFS 340
Q+C + S+ Y + LV + + + +F P ++D+++ P R + +
Sbjct: 167 QNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPS---GEWDIVALPGRR-NENPDDSTYV 222
Query: 341 VLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
+ F ++R ++ I + +PC+LI L+ + F++ + G
Sbjct: 223 DITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSDCG 263
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 69.3 bits (162), Expect = 3e-11
Identities = 48/236 (20%), Positives = 105/236 (44%), Gaps = 6/236 (2%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+ E L ++Y P P ++ + + + V E++ + + +Q W D +L
Sbjct: 35 LFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLK 94
Query: 209 FLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
+ + +++ ++IW+PD YN T LL+ + G++ +
Sbjct: 95 WNPSGYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVTTKTKALLKYT--GEVTWIPPAIF 152
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFP- 326
K+ C +++ FP D Q+C + GS++Y ++ S S+N ++ +I P
Sbjct: 153 KSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGS-SMNLKDYWESGEWAIIKAPG 211
Query: 327 YR-NFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y+ + + E + + S +R ++ I + +PC+LI L+ + F++ + G
Sbjct: 212 YKHDIKYNCCEEIYPDITYSLYSRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCG 267
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 69.3 bits (162), Expect = 3e-11
Identities = 58/256 (22%), Positives = 114/256 (44%), Gaps = 12/256 (4%)
Query: 136 RSINDAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMD 195
R+ A K + +L ++Y N+ P V I + + + E + +
Sbjct: 15 RAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAY 74
Query: 196 CYFRQYWRDTRLSFLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRIS 254
+ RQ W D L++ SI++ + +WRPD YN N +LR
Sbjct: 75 LWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYD 134
Query: 255 QHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQL-VYQWQNSQSVN-FV 312
G I + K+ C +++ FP D Q C L GS+ Y+ Q+ ++ +S ++ F+
Sbjct: 135 --GLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFI 192
Query: 313 PGMTLSQFDLISFP-YRN-FTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLS 370
+ ++++ P +N ++ + + + LKR + ++++ + +PC+LI L+
Sbjct: 193 EDV---EWEVHGMPAVKNVISYGCCSEPYPDVTFTLLLKRRSSFYIVNLLIPCVLISFLA 249
Query: 371 WVSFWIHREVGSGEIV 386
+SF++ SGE V
Sbjct: 250 PLSFYL--PAASGEKV 263
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 68.5 bits (160), Expect = 6e-11
Identities = 55/245 (22%), Positives = 105/245 (42%), Gaps = 16/245 (6%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL 210
E L Y++S P G V +++ + ++E D + S Y W D RLS+
Sbjct: 32 EKLFSGYDSSVRPAREVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLEWTDYRLSWD 91
Query: 211 GPIRSLSLSIKML-ERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKA 269
S+++ E +W PD N + + ++ +S G + + ++
Sbjct: 92 PAEHDGIDSLRITAESVWLPDVVLLNNNDGNFD-VALDISVV-VSSDGSVRWQPPGIYRS 149
Query: 270 KCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQ------WQNSQSVNFVPGMTL--SQFD 321
C +++ FP D Q+C ++ SY+Y + ++ Q Q Q ++ G + Q++
Sbjct: 150 SCSIQVTYFPFDWQNCTMVFSSYSYDSSEVSLQTGLGPDGQGHQEIHIHEGTFIENGQWE 209
Query: 322 LISFPYR-----NFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
+I P R REG + ++R ++L+ V PCILI +L+ F++
Sbjct: 210 IIHKPSRLIQPPGDPRGGREGQRQEVIFYLIIRRKPLFYLVNVIAPCILITLLAIFVFYL 269
Query: 377 HREVG 381
+ G
Sbjct: 270 PPDAG 274
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 68.1 bits (159), Expect = 7e-11
Identities = 47/236 (19%), Positives = 105/236 (44%), Gaps = 6/236 (2%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+ E L ++Y P P ++ + + + V E++ + + +Q W D +L
Sbjct: 36 LFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLK 95
Query: 209 FLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
+ + +++ ++IW+PD YN LL+ + G++ +
Sbjct: 96 WNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYT--GEVTWIPPAIF 153
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFP- 326
K+ C +++ FP D Q+C + GS++Y ++ S S+N ++ +I P
Sbjct: 154 KSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGS-SMNLKDYWESGEWAIIKAPG 212
Query: 327 YR-NFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y+ + + E + + S ++R ++ I + +PC+LI L+ + F++ + G
Sbjct: 213 YKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCG 268
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 68.1 bits (159), Expect = 7e-11
Identities = 47/236 (19%), Positives = 105/236 (44%), Gaps = 6/236 (2%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+ E L ++Y P P ++ + + + V E++ + + +Q W D +L
Sbjct: 7 LFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLK 66
Query: 209 FLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
+ + +++ ++IW+PD YN LL+ + G++ +
Sbjct: 67 WNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYT--GEVTWIPPAIF 124
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFP- 326
K+ C +++ FP D Q+C + GS++Y ++ S S+N ++ +I P
Sbjct: 125 KSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGS-SMNLKDYWESGEWAIIKAPG 183
Query: 327 YR-NFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y+ + + E + + S ++R ++ I + +PC+LI L+ + F++ + G
Sbjct: 184 YKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCG 239
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 68.1 bits (159), Expect = 7e-11
Identities = 47/236 (19%), Positives = 105/236 (44%), Gaps = 6/236 (2%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+ E L ++Y P P ++ + + + V E++ + + +Q W D +L
Sbjct: 37 LFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLK 96
Query: 209 FLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
+ + +++ ++IW+PD YN LL+ + G++ +
Sbjct: 97 WNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYT--GEVTWIPPAIF 154
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFP- 326
K+ C +++ FP D Q+C + GS++Y ++ S S+N ++ +I P
Sbjct: 155 KSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGS-SMNLKDYWESGEWAIIKAPG 213
Query: 327 YR-NFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y+ + + E + + S ++R ++ I + +PC+LI L+ + F++ + G
Sbjct: 214 YKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCG 269
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 68.1 bits (159), Expect = 7e-11
Identities = 47/236 (19%), Positives = 105/236 (44%), Gaps = 6/236 (2%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+ E L ++Y P P ++ + + + V E++ + + +Q W D +L
Sbjct: 36 LFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLK 95
Query: 209 FLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
+ + +++ ++IW+PD YN LL+ + G++ +
Sbjct: 96 WNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYT--GEVTWIPPAIF 153
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFP- 326
K+ C +++ FP D Q+C + GS++Y ++ S S+N ++ +I P
Sbjct: 154 KSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGS-SMNLKDYWESGEWAIIKAPG 212
Query: 327 YR-NFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y+ + + E + + S ++R ++ I + +PC+LI L+ + F++ + G
Sbjct: 213 YKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCG 268
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 68.1 bits (159), Expect = 7e-11
Identities = 47/236 (19%), Positives = 105/236 (44%), Gaps = 6/236 (2%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+ E L ++Y P P ++ + + + V E++ + + +Q W D +L
Sbjct: 38 LFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLK 97
Query: 209 FLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
+ + +++ ++IW+PD YN LL+ + G++ +
Sbjct: 98 WNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYT--GEVTWIPPAIF 155
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFP- 326
K+ C +++ FP D Q+C + GS++Y ++ S S+N ++ +I P
Sbjct: 156 KSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGS-SMNLKDYWESGEWAIIKAPG 214
Query: 327 YR-NFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y+ + + E + + S ++R ++ I + +PC+LI L+ + F++ + G
Sbjct: 215 YKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCG 270
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 68.1 bits (159), Expect = 7e-11
Identities = 47/236 (19%), Positives = 105/236 (44%), Gaps = 6/236 (2%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+ E L ++Y P P ++ + + + V E++ + + +Q W D +L
Sbjct: 38 LFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLK 97
Query: 209 FLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
+ + +++ ++IW+PD YN LL+ + G++ +
Sbjct: 98 WNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYT--GEVTWIPPAIF 155
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFP- 326
K+ C +++ FP D Q+C + GS++Y ++ S S+N ++ +I P
Sbjct: 156 KSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGS-SMNLKDYWESGEWAIIKAPG 214
Query: 327 YR-NFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y+ + + E + + S ++R ++ I + +PC+LI L+ + F++ + G
Sbjct: 215 YKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCG 270
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 68.1 bits (159), Expect = 7e-11
Identities = 47/236 (19%), Positives = 105/236 (44%), Gaps = 6/236 (2%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+ E L ++Y P P ++ + + + V E++ + + +Q W D +L
Sbjct: 37 LFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLK 96
Query: 209 FLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
+ + +++ ++IW+PD YN LL+ + G++ +
Sbjct: 97 WNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYT--GEVTWIPPAIF 154
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFP- 326
K+ C +++ FP D Q+C + GS++Y ++ S S+N ++ +I P
Sbjct: 155 KSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGS-SMNLKDYWESGEWAIIKAPG 213
Query: 327 YR-NFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y+ + + E + + S ++R ++ I + +PC+LI L+ + F++ + G
Sbjct: 214 YKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCG 269
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 68.1 bits (159), Expect = 7e-11
Identities = 47/236 (19%), Positives = 105/236 (44%), Gaps = 6/236 (2%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+ E L ++Y P P ++ + + + V E++ + + +Q W D +L
Sbjct: 38 LFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLK 97
Query: 209 FLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
+ + +++ ++IW+PD YN LL+ + G++ +
Sbjct: 98 WNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYT--GEVTWIPPAIF 155
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFP- 326
K+ C +++ FP D Q+C + GS++Y ++ S S+N ++ +I P
Sbjct: 156 KSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGS-SMNLKDYWESGEWAIIKAPG 214
Query: 327 YR-NFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y+ + + E + + S ++R ++ I + +PC+LI L+ + F++ + G
Sbjct: 215 YKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCG 270
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 68.1 bits (159), Expect = 7e-11
Identities = 47/236 (19%), Positives = 105/236 (44%), Gaps = 6/236 (2%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+ E L ++Y P P ++ + + + V E++ + + +Q W D +L
Sbjct: 38 LFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLK 97
Query: 209 FLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
+ + +++ ++IW+PD YN LL+ + G++ +
Sbjct: 98 WNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYT--GEVTWIPPAIF 155
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFP- 326
K+ C +++ FP D Q+C + GS++Y ++ S S+N ++ +I P
Sbjct: 156 KSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGS-SMNLKDYWESGEWAIIKAPG 214
Query: 327 YR-NFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y+ + + E + + S ++R ++ I + +PC+LI L+ + F++ + G
Sbjct: 215 YKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCG 270
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 68.1 bits (159), Expect = 7e-11
Identities = 47/236 (19%), Positives = 105/236 (44%), Gaps = 6/236 (2%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+ E L ++Y P P ++ + + + V E++ + + +Q W D +L
Sbjct: 38 LFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLK 97
Query: 209 FLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
+ + +++ ++IW+PD YN LL+ + G++ +
Sbjct: 98 WNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYT--GEVTWIPPAIF 155
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFP- 326
K+ C +++ FP D Q+C + GS++Y ++ S S+N ++ +I P
Sbjct: 156 KSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGS-SMNLKDYWESGEWAIIKAPG 214
Query: 327 YR-NFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y+ + + E + + S ++R ++ I + +PC+LI L+ + F++ + G
Sbjct: 215 YKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCG 270
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 68.1 bits (159), Expect = 7e-11
Identities = 47/236 (19%), Positives = 105/236 (44%), Gaps = 6/236 (2%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+ E L ++Y P P ++ + + + V E++ + + +Q W D +L
Sbjct: 38 LFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLK 97
Query: 209 FLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
+ + +++ ++IW+PD YN LL+ + G++ +
Sbjct: 98 WNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYT--GEVTWIPPAIF 155
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFP- 326
K+ C +++ FP D Q+C + GS++Y ++ S S+N ++ +I P
Sbjct: 156 KSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGS-SMNLKDYWESGEWAIIKAPG 214
Query: 327 YR-NFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y+ + + E + + S ++R ++ I + +PC+LI L+ + F++ + G
Sbjct: 215 YKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCG 270
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 68.1 bits (159), Expect = 7e-11
Identities = 47/236 (19%), Positives = 105/236 (44%), Gaps = 6/236 (2%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+ E L ++Y P P ++ + + + V E++ + + +Q W D +L
Sbjct: 37 LFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLK 96
Query: 209 FLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
+ + +++ ++IW+PD YN LL+ + G++ +
Sbjct: 97 WNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYT--GEVTWIPPAIF 154
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFP- 326
K+ C +++ FP D Q+C + GS++Y ++ S S+N ++ +I P
Sbjct: 155 KSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGS-SMNLKDYWESGEWAIIKAPG 213
Query: 327 YR-NFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y+ + + E + + S ++R ++ I + +PC+LI L+ + F++ + G
Sbjct: 214 YKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCG 269
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 68.1 bits (159), Expect = 7e-11
Identities = 47/236 (19%), Positives = 105/236 (44%), Gaps = 6/236 (2%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+ E L ++Y P P ++ + + + V E++ + + +Q W D +L
Sbjct: 32 LFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLK 91
Query: 209 FLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
+ + +++ ++IW+PD YN LL+ + G++ +
Sbjct: 92 WNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYT--GEVTWIPPAIF 149
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFP- 326
K+ C +++ FP D Q+C + GS++Y ++ S S+N ++ +I P
Sbjct: 150 KSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGS-SMNLKDYWESGEWAIIKAPG 208
Query: 327 YR-NFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y+ + + E + + S ++R ++ I + +PC+LI L+ + F++ + G
Sbjct: 209 YKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCG 264
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 67.7 bits (158), Expect = 1e-10
Identities = 54/243 (22%), Positives = 105/243 (43%), Gaps = 16/243 (6%)
Query: 153 LLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGP 212
L Y++S P G V +++ + ++E D + S Y W D RLS+
Sbjct: 34 LFSGYDSSVRPAREVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLEWTDYRLSWDPA 93
Query: 213 IRSLSLSIKML-ERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKC 271
S+++ E +W PD N + + + ++ +S G + + ++ C
Sbjct: 94 EHDGIDSLRITAESVWLPDVVLLNNNDGNFY-VALDISVV-VSSDGSVRWQPPGIYRSSC 151
Query: 272 PMELRNFPMDRQSCPLILGSYAYSNQQLVYQ------WQNSQSVNFVPGMTL--SQFDLI 323
+++ FP D Q+C ++ SY+Y + ++ Q Q Q ++ G + Q+++I
Sbjct: 152 SIQVTYFPFDWQNCTMVFSSYSYDSSEVSLQTGLGPDGQGHQEIHIHEGTFIENGQWEII 211
Query: 324 SFPYR-----NFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHR 378
P R REG + ++R ++L+ V PCILI +L+ F++
Sbjct: 212 HKPSRLIQPPGDPRGGREGQRQEVIFYLIIRRKPLFYLVNVIAPCILITLLAIFVFYLPP 271
Query: 379 EVG 381
+ G
Sbjct: 272 DAG 274
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 66.5 bits (155), Expect = 2e-10
Identities = 55/245 (22%), Positives = 104/245 (42%), Gaps = 16/245 (6%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL 210
E L Y++S P G V +++ + ++E D + S Y W D RLS+
Sbjct: 32 EKLFSGYDSSVRPAREVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLEWTDYRLSWD 91
Query: 211 GPIRSLSLSIKML-ERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKA 269
S+++ E +W PD N + + ++ +S G + + ++
Sbjct: 92 PAEHDGIDSLRITAESVWLPDVVLLNNNDGNFD-VALDISVV-VSSDGSVRWQPPGIYRS 149
Query: 270 KCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQ------WQNSQSVNFVPGMTL--SQFD 321
C +++ FP D Q+C ++ SY+Y + ++ Q Q Q ++ G + Q++
Sbjct: 150 SCSIQVTYFPFDWQNCTMVFSSYSYDSSEVSLQTGLGPDGQGHQEIHIHEGTFIENGQWE 209
Query: 322 LISFPYR-----NFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
I P R REG + ++R ++L+ V PCILI +L+ F++
Sbjct: 210 NIHKPSRLIQPPGDPRGGREGQRQEVIFYLIIRRKPLFYLVNVIAPCILITLLAIFVFYL 269
Query: 377 HREVG 381
+ G
Sbjct: 270 PPDAG 274
>D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor
protein.
Length = 478
Score = 65.7 bits (153), Expect = 4e-10
Identities = 53/234 (22%), Positives = 107/234 (45%), Gaps = 18/234 (7%)
Query: 153 LLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF--- 209
LL NY P PT V ++++ ++ V E + + ++RQYW D L +
Sbjct: 41 LLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPE 100
Query: 210 -LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPN-KLLRISQHGDILYSMRLTI 267
I LS+ + IW PD + +V PN + I G++ L +
Sbjct: 101 DFDNITKLSIP---TDSIWVPDILI----NEFVDVGKSPNIPYVYIRHQGEVQNYKPLQV 153
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQL-VYQWQNSQSVNFVPGMTLSQ--FDLIS 324
C +++ NFP D Q+C L S+ ++ Q + + W+ + V + ++Q ++L+
Sbjct: 154 VTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLG 213
Query: 325 -FPY-RNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
PY R F+ ++ ++ ++R ++++ + +P I ++V+ V F++
Sbjct: 214 VLPYFREFSM-ESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYL 266
>BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 484
Score = 65.7 bits (153), Expect = 4e-10
Identities = 53/234 (22%), Positives = 107/234 (45%), Gaps = 18/234 (7%)
Query: 153 LLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF--- 209
LL NY P PT V ++++ ++ V E + + ++RQYW D L +
Sbjct: 47 LLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPE 106
Query: 210 -LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPN-KLLRISQHGDILYSMRLTI 267
I LS+ + IW PD + +V PN + I G++ L +
Sbjct: 107 DFDNITKLSIP---TDSIWVPDILI----NEFVDVGKSPNIPYVYIRHQGEVQNYKPLQV 159
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQL-VYQWQNSQSVNFVPGMTLSQ--FDLIS 324
C +++ NFP D Q+C L S+ ++ Q + + W+ + V + ++Q ++L+
Sbjct: 160 VTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLG 219
Query: 325 -FPY-RNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
PY R F+ ++ ++ ++R ++++ + +P I ++V+ V F++
Sbjct: 220 VLPYFREFSM-ESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYL 272
>BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 65.7 bits (153), Expect = 4e-10
Identities = 53/234 (22%), Positives = 107/234 (45%), Gaps = 18/234 (7%)
Query: 153 LLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF--- 209
LL NY P PT V ++++ ++ V E + + ++RQYW D L +
Sbjct: 41 LLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPE 100
Query: 210 -LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPN-KLLRISQHGDILYSMRLTI 267
I LS+ + IW PD + +V PN + I G++ L +
Sbjct: 101 DFDNITKLSIP---TDSIWVPDILI----NEFVDVGKSPNIPYVYIRHQGEVQNYKPLQV 153
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQL-VYQWQNSQSVNFVPGMTLSQ--FDLIS 324
C +++ NFP D Q+C L S+ ++ Q + + W+ + V + ++Q ++L+
Sbjct: 154 VTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLG 213
Query: 325 -FPY-RNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
PY R F+ ++ ++ ++R ++++ + +P I ++V+ V F++
Sbjct: 214 VLPYFREFSM-ESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYL 266
>BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 65.7 bits (153), Expect = 4e-10
Identities = 53/234 (22%), Positives = 107/234 (45%), Gaps = 18/234 (7%)
Query: 153 LLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF--- 209
LL NY P PT V ++++ ++ V E + + ++RQYW D L +
Sbjct: 41 LLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPE 100
Query: 210 -LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPN-KLLRISQHGDILYSMRLTI 267
I LS+ + IW PD + +V PN + I G++ L +
Sbjct: 101 DFDNITKLSIP---TDSIWVPDILI----NEFVDVGKSPNIPYVYIRHQGEVQNYKPLQV 153
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQL-VYQWQNSQSVNFVPGMTLSQ--FDLIS 324
C +++ NFP D Q+C L S+ ++ Q + + W+ + V + ++Q ++L+
Sbjct: 154 VTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLG 213
Query: 325 -FPY-RNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
PY R F+ ++ ++ ++R ++++ + +P I ++V+ V F++
Sbjct: 214 VLPYFREFSM-ESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYL 266
>AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor
protein.
Length = 478
Score = 65.7 bits (153), Expect = 4e-10
Identities = 53/234 (22%), Positives = 107/234 (45%), Gaps = 18/234 (7%)
Query: 153 LLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF--- 209
LL NY P PT V ++++ ++ V E + + ++RQYW D L +
Sbjct: 41 LLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPE 100
Query: 210 -LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPN-KLLRISQHGDILYSMRLTI 267
I LS+ + IW PD + +V PN + I G++ L +
Sbjct: 101 DFDNITKLSIP---TDSIWVPDILI----NEFVDVGKSPNIPYVYIRHQGEVQNYKPLQV 153
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQL-VYQWQNSQSVNFVPGMTLSQ--FDLIS 324
C +++ NFP D Q+C L S+ ++ Q + + W+ + V + ++Q ++L+
Sbjct: 154 VTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLG 213
Query: 325 -FPY-RNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
PY R F+ ++ ++ ++R ++++ + +P I ++V+ V F++
Sbjct: 214 VLPYFREFSM-ESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYL 266
>AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3
receptor protein.
Length = 478
Score = 65.7 bits (153), Expect = 4e-10
Identities = 53/234 (22%), Positives = 107/234 (45%), Gaps = 18/234 (7%)
Query: 153 LLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF--- 209
LL NY P PT V ++++ ++ V E + + ++RQYW D L +
Sbjct: 41 LLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPE 100
Query: 210 -LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPN-KLLRISQHGDILYSMRLTI 267
I LS+ + IW PD + +V PN + I G++ L +
Sbjct: 101 DFDNITKLSIP---TDSIWVPDILI----NEFVDVGKSPNIPYVYIRHQGEVQNYKPLQV 153
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQL-VYQWQNSQSVNFVPGMTLSQ--FDLIS 324
C +++ NFP D Q+C L S+ ++ Q + + W+ + V + ++Q ++L+
Sbjct: 154 VTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLG 213
Query: 325 -FPY-RNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
PY R F+ ++ ++ ++R ++++ + +P I ++V+ V F++
Sbjct: 214 VLPYFREFSM-ESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYL 266
>AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor
protein.
Length = 510
Score = 65.7 bits (153), Expect = 4e-10
Identities = 53/234 (22%), Positives = 107/234 (45%), Gaps = 18/234 (7%)
Query: 153 LLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF--- 209
LL NY P PT V ++++ ++ V E + + ++RQYW D L +
Sbjct: 41 LLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPE 100
Query: 210 -LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPN-KLLRISQHGDILYSMRLTI 267
I LS+ + IW PD + +V PN + I G++ L +
Sbjct: 101 DFDNITKLSIP---TDSIWVPDILI----NEFVDVGKSPNIPYVYIRHQGEVQNYKPLQV 153
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQL-VYQWQNSQSVNFVPGMTLSQ--FDLIS 324
C +++ NFP D Q+C L S+ ++ Q + + W+ + V + ++Q ++L+
Sbjct: 154 VTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLG 213
Query: 325 -FPY-RNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
PY R F+ ++ ++ ++R ++++ + +P I ++V+ V F++
Sbjct: 214 VLPYFREFSM-ESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYL 266
>AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine
receptor 3A protein.
Length = 478
Score = 65.7 bits (153), Expect = 4e-10
Identities = 53/234 (22%), Positives = 107/234 (45%), Gaps = 18/234 (7%)
Query: 153 LLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF--- 209
LL NY P PT V ++++ ++ V E + + ++RQYW D L +
Sbjct: 41 LLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPE 100
Query: 210 -LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPN-KLLRISQHGDILYSMRLTI 267
I LS+ + IW PD + +V PN + I G++ L +
Sbjct: 101 DFDNITKLSIP---TDSIWVPDILI----NEFVDVGKSPNIPYVYIRHQGEVQNYKPLQV 153
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQL-VYQWQNSQSVNFVPGMTLSQ--FDLIS 324
C +++ NFP D Q+C L S+ ++ Q + + W+ + V + ++Q ++L+
Sbjct: 154 VTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLG 213
Query: 325 -FPY-RNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
PY R F+ ++ ++ ++R ++++ + +P I ++V+ V F++
Sbjct: 214 VLPYFREFSM-ESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYL 266
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 64.1 bits (149), Expect = 1e-09
Identities = 50/245 (20%), Positives = 104/245 (42%), Gaps = 11/245 (4%)
Query: 143 SKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYW 202
S++ T ++ L K+Y + P V + + + V E++ + + +Q W
Sbjct: 21 SEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVDEVNQIVTTNVRLKQQW 80
Query: 203 RDTRLSF----LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGD 258
D L + G ++ + + E+IWRPD YN + LL+ + H
Sbjct: 81 VDYNLKWNPDDYGGVKKIHIPS---EKIWRPDLVLYNNADGDFAIVKFTKVLLQYTGH-- 135
Query: 259 ILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQS--VNFVPGMT 316
I ++ K+ C + + +FP D Q+C + LG++ Y + ++ Q NF+
Sbjct: 136 ITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPESDQPDLSNFMESGE 195
Query: 317 LSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
+ + + + + + F ++R YF++ V +PC+L L+ + F++
Sbjct: 196 WVIKESRGWKHSVTYSCCPDTPYLDITYHFVMQRLPLYFIVNVIIPCLLFSFLTGLVFYL 255
Query: 377 HREVG 381
+ G
Sbjct: 256 PTDSG 260
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 64.1 bits (149), Expect = 1e-09
Identities = 50/245 (20%), Positives = 104/245 (42%), Gaps = 11/245 (4%)
Query: 143 SKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYW 202
S++ T ++ L K+Y + P V + + + V E++ + + +Q W
Sbjct: 21 SEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVDEVNQIVTTNVRLKQQW 80
Query: 203 RDTRLSF----LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGD 258
D L + G ++ + + E+IWRPD YN + LL+ + H
Sbjct: 81 VDYNLKWNPDDYGGVKKIHIPS---EKIWRPDLVLYNNADGDFAIVKFTKVLLQYTGH-- 135
Query: 259 ILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQS--VNFVPGMT 316
I ++ K+ C + + +FP D Q+C + LG++ Y + ++ Q NF+
Sbjct: 136 ITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPESDQPDLSNFMESGE 195
Query: 317 LSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
+ + + + + + F ++R YF++ V +PC+L L+ + F++
Sbjct: 196 WVIKESRGWKHSVTYSCCPDTPYLDITYHFVMQRLPLYFIVNVIIPCLLFSFLTGLVFYL 255
Query: 377 HREVG 381
+ G
Sbjct: 256 PTDSG 260
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 64.1 bits (149), Expect = 1e-09
Identities = 50/245 (20%), Positives = 104/245 (42%), Gaps = 11/245 (4%)
Query: 143 SKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYW 202
S++ T ++ L K+Y + P V + + + V E++ + + +Q W
Sbjct: 21 SEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVDEVNQIVTTNVRLKQQW 80
Query: 203 RDTRLSF----LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGD 258
D L + G ++ + + E+IWRPD YN + LL+ + H
Sbjct: 81 VDYNLKWNPDDYGGVKKIHIPS---EKIWRPDLVLYNNADGDFAIVKFTKVLLQYTGH-- 135
Query: 259 ILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQS--VNFVPGMT 316
I ++ K+ C + + +FP D Q+C + LG++ Y + ++ Q NF+
Sbjct: 136 ITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPESDQPDLSNFMESGE 195
Query: 317 LSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
+ + + + + + F ++R YF++ V +PC+L L+ + F++
Sbjct: 196 WVIKESRGWKHSVTYSCCPDTPYLDITYHFVMQRLPLYFIVNVIIPCLLFSFLTGLVFYL 255
Query: 377 HREVG 381
+ G
Sbjct: 256 PTDSG 260
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 64.1 bits (149), Expect = 1e-09
Identities = 50/245 (20%), Positives = 104/245 (42%), Gaps = 11/245 (4%)
Query: 143 SKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYW 202
S++ T ++ L K+Y + P V + + + V E++ + + +Q W
Sbjct: 21 SEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVDEVNQIVTTNVRLKQQW 80
Query: 203 RDTRLSF----LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGD 258
D L + G ++ + + E+IWRPD YN + LL+ + H
Sbjct: 81 VDYNLKWNPDDYGGVKKIHIPS---EKIWRPDLVLYNNADGDFAIVKFTKVLLQYTGH-- 135
Query: 259 ILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQS--VNFVPGMT 316
I ++ K+ C + + +FP D Q+C + LG++ Y + ++ Q NF+
Sbjct: 136 ITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPESDQPDLSNFMESGE 195
Query: 317 LSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
+ + + + + + F ++R YF++ V +PC+L L+ + F++
Sbjct: 196 WVIKESRGWKHSVTYSCCPDTPYLDITYHFVMQRLPLYFIVNVIIPCLLFSFLTGLVFYL 255
Query: 377 HREVG 381
+ G
Sbjct: 256 PTDSG 260
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 64.1 bits (149), Expect = 1e-09
Identities = 50/245 (20%), Positives = 104/245 (42%), Gaps = 11/245 (4%)
Query: 143 SKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYW 202
S++ T ++ L K+Y + P V + + + V E++ + + +Q W
Sbjct: 21 SEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVDEVNQIVTTNVRLKQQW 80
Query: 203 RDTRLSF----LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGD 258
D L + G ++ + + E+IWRPD YN + LL+ + H
Sbjct: 81 VDYNLKWNPDDYGGVKKIHIPS---EKIWRPDLVLYNNADGDFAIVKFTKVLLQYTGH-- 135
Query: 259 ILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQS--VNFVPGMT 316
I ++ K+ C + + +FP D Q+C + LG++ Y + ++ Q NF+
Sbjct: 136 ITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPESDQPDLSNFMESGE 195
Query: 317 LSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
+ + + + + + F ++R YF++ V +PC+L L+ + F++
Sbjct: 196 WVIKESRGWKHSVTYSCCPDTPYLDITYHFVMQRLPLYFIVNVIIPCLLFSFLTGLVFYL 255
Query: 377 HREVG 381
+ G
Sbjct: 256 PTDSG 260
>S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type 3AS
receptor subunit protein.
Length = 478
Score = 63.7 bits (148), Expect = 2e-09
Identities = 53/234 (22%), Positives = 106/234 (45%), Gaps = 18/234 (7%)
Query: 153 LLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF--- 209
LL NY P PT V ++++ ++ V E + + ++RQYW D L +
Sbjct: 41 LLTNYTKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPE 100
Query: 210 -LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPN-KLLRISQHGDILYSMRLTI 267
I LS+ + IW PD + V PN + I G++ L +
Sbjct: 101 DFDNITKLSIP---TDSIWVPDILI----NELVDVGKSPNIPYVYIRHQGEVQNYKPLQV 153
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQL-VYQWQNSQSVNFVPGMTLSQ--FDLIS 324
C +++ NFP D Q+C L S+ ++ Q + + W+ + V + ++Q ++L+
Sbjct: 154 VTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLG 213
Query: 325 -FPY-RNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
PY R F+ ++ ++ ++R ++++ + +P I ++V+ V F++
Sbjct: 214 VLPYFREFSM-ESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYL 266
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 63.3 bits (147), Expect = 2e-09
Identities = 49/245 (20%), Positives = 115/245 (46%), Gaps = 8/245 (3%)
Query: 140 DAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFR 199
+++++N ++L +L + Y+ P V + I + V E + + + + +
Sbjct: 23 NSIAENEDALLRHLFQGYQKWVRPVLHSNDTIKVYFGLKISQLVDVDEKNQLMTTNVWLK 82
Query: 200 QYWRDTRLSFLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGD 258
Q W D +L + SIK+ E +W PD + ++ K++ + +G
Sbjct: 83 QEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEG-SLMTKVI-VKSNGT 140
Query: 259 ILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLS 318
++++ + K+ C M++ FP DRQ+C + GS+ Y + N ++V+
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILIN-ENVDRKDFFDNG 199
Query: 319 QFDLISFPYRNFTFTRREGDFS--VLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
++++++ + RR+G +S + SF L+R ++ + + +PC+ + L+ + F++
Sbjct: 200 EWEILN--AKGMKGNRRDGVYSYPFITYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYL 257
Query: 377 HREVG 381
+ G
Sbjct: 258 PSDEG 262
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 63.3 bits (147), Expect = 2e-09
Identities = 49/245 (20%), Positives = 115/245 (46%), Gaps = 8/245 (3%)
Query: 140 DAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFR 199
+++++N ++L +L + Y+ P V + I + V E + + + + +
Sbjct: 23 NSIAENEDALLRHLFQGYQKWVRPVLHSNDTIKVYFGLKISQLVDVDEKNQLMTTNVWLK 82
Query: 200 QYWRDTRLSFLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGD 258
Q W D +L + SIK+ E +W PD + ++ K++ + +G
Sbjct: 83 QEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEG-SLMTKVI-VKSNGT 140
Query: 259 ILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLS 318
++++ + K+ C M++ FP DRQ+C + GS+ Y + N ++V+
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILIN-ENVDRKDFFDNG 199
Query: 319 QFDLISFPYRNFTFTRREGDFS--VLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
++++++ + RR+G +S + SF L+R ++ + + +PC+ + L+ + F++
Sbjct: 200 EWEILN--AKGMKGNRRDGVYSYPFITYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYL 257
Query: 377 HREVG 381
+ G
Sbjct: 258 PSDEG 262
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 63.3 bits (147), Expect = 2e-09
Identities = 49/245 (20%), Positives = 115/245 (46%), Gaps = 8/245 (3%)
Query: 140 DAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFR 199
+++++N ++L +L + Y+ P V + I + V E + + + + +
Sbjct: 23 NSIAENEDALLRHLFQGYQKWVRPVLHSNDTIKVYFGLKISQLVDVDEKNQLMTTNVWLK 82
Query: 200 QYWRDTRLSFLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGD 258
Q W D +L + SIK+ E +W PD + ++ K++ + +G
Sbjct: 83 QEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEG-SLMTKVI-VKSNGT 140
Query: 259 ILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLS 318
++++ + K+ C M++ FP DRQ+C + GS+ Y + N ++V+
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILIN-ENVDRKDFFDNG 199
Query: 319 QFDLISFPYRNFTFTRREGDFS--VLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
++++++ + RR+G +S + SF L+R ++ + + +PC+ + L+ + F++
Sbjct: 200 EWEILN--AKGMKGNRRDGVYSYPFITYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYL 257
Query: 377 HREVG 381
+ G
Sbjct: 258 PSDEG 262
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 63.3 bits (147), Expect = 2e-09
Identities = 49/245 (20%), Positives = 115/245 (46%), Gaps = 8/245 (3%)
Query: 140 DAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFR 199
+++++N ++L +L + Y+ P V + I + V E + + + + +
Sbjct: 23 NSIAENEDALLRHLFQGYQKWVRPVLHSNDTIKVYFGLKISQLVDVDEKNQLMTTNVWLK 82
Query: 200 QYWRDTRLSFLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGD 258
Q W D +L + SIK+ E +W PD + ++ K++ + +G
Sbjct: 83 QEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEG-SLMTKVI-VKSNGT 140
Query: 259 ILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLS 318
++++ + K+ C M++ FP DRQ+C + GS+ Y + N ++V+
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILIN-ENVDRKDFFDNG 199
Query: 319 QFDLISFPYRNFTFTRREGDFS--VLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
++++++ + RR+G +S + SF L+R ++ + + +PC+ + L+ + F++
Sbjct: 200 EWEILN--AKGMKGNRRDGVYSYPFITYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYL 257
Query: 377 HREVG 381
+ G
Sbjct: 258 PSDEG 262
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 63.3 bits (147), Expect = 2e-09
Identities = 49/245 (20%), Positives = 115/245 (46%), Gaps = 8/245 (3%)
Query: 140 DAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFR 199
+++++N ++L +L + Y+ P V + I + V E + + + + +
Sbjct: 23 NSIAENEDALLRHLFQGYQKWVRPVLHSNDTIKVYFGLKISQLVDVDEKNQLMTTNVWLK 82
Query: 200 QYWRDTRLSFLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGD 258
Q W D +L + SIK+ E +W PD + ++ K++ + +G
Sbjct: 83 QEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEG-SLMTKVI-VKSNGT 140
Query: 259 ILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLS 318
++++ + K+ C M++ FP DRQ+C + GS+ Y + N ++V+
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILIN-ENVDRKDFFDNG 199
Query: 319 QFDLISFPYRNFTFTRREGDFS--VLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
++++++ + RR+G +S + SF L+R ++ + + +PC+ + L+ + F++
Sbjct: 200 EWEILN--AKGMKGNRRDGVYSYPFITYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYL 257
Query: 377 HREVG 381
+ G
Sbjct: 258 PSDEG 262
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 63.3 bits (147), Expect = 2e-09
Identities = 49/245 (20%), Positives = 115/245 (46%), Gaps = 8/245 (3%)
Query: 140 DAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFR 199
+++++N ++L +L + Y+ P V + I + V E + + + + +
Sbjct: 23 NSIAENEDALLRHLFQGYQKWVRPVLHSNDTIKVYFGLKISQLVDVDEKNQLMTTNVWLK 82
Query: 200 QYWRDTRLSFLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGD 258
Q W D +L + SIK+ E +W PD + ++ K++ + +G
Sbjct: 83 QEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEG-SLMTKVI-VKSNGT 140
Query: 259 ILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLS 318
++++ + K+ C M++ FP DRQ+C + GS+ Y + N ++V+
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILIN-ENVDRKDFFDNG 199
Query: 319 QFDLISFPYRNFTFTRREGDFS--VLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
++++++ + RR+G +S + SF L+R ++ + + +PC+ + L+ + F++
Sbjct: 200 EWEILN--AKGMKGNRRDGVYSYPFITYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYL 257
Query: 377 HREVG 381
+ G
Sbjct: 258 PSDEG 262
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 61.3 bits (142), Expect = 8e-09
Identities = 51/236 (21%), Positives = 98/236 (41%), Gaps = 6/236 (2%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L+ L Y P +V+ + I + V E + + + + +Q W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 209 FLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
+ SI++ E IWRPD YN +T K + G + ++
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNADGDF-AVTHLTKA-HLFHDGRVQWTPPAIY 157
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQ--LVYQWQNSQSVNFVPGMTLSQFDLISF 325
K+ C +++ FP D+Q+C + GS+ Y + LV ++F D +
Sbjct: 158 KSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVDAVG- 216
Query: 326 PYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y + + + +F ++R ++ I + +PC+LI L+ + F++ E G
Sbjct: 217 TYNTRKYECCAEIYPDITYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECG 272
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 61.3 bits (142), Expect = 8e-09
Identities = 51/236 (21%), Positives = 98/236 (41%), Gaps = 6/236 (2%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L+ L Y P +V+ + I + V E + + + + +Q W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 209 FLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
+ SI++ E IWRPD YN +T K + G + ++
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNADGDF-AVTHLTKA-HLFHDGRVQWTPPAIY 157
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQ--LVYQWQNSQSVNFVPGMTLSQFDLISF 325
K+ C +++ FP D+Q+C + GS+ Y + LV ++F D +
Sbjct: 158 KSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVDAVG- 216
Query: 326 PYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y + + + +F ++R ++ I + +PC+LI L+ + F++ E G
Sbjct: 217 TYNTRKYECCAEIYPDITYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECG 272
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 61.3 bits (142), Expect = 8e-09
Identities = 51/236 (21%), Positives = 98/236 (41%), Gaps = 6/236 (2%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L+ L Y P +V+ + I + V E + + + + +Q W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 209 FLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
+ SI++ E IWRPD YN +T K + G + ++
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNADGDF-AVTHLTKA-HLFHDGRVQWTPPAIY 132
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQ--LVYQWQNSQSVNFVPGMTLSQFDLISF 325
K+ C +++ FP D+Q+C + GS+ Y + LV ++F D +
Sbjct: 133 KSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVDAVG- 191
Query: 326 PYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y + + + +F ++R ++ I + +PC+LI L+ + F++ E G
Sbjct: 192 TYNTRKYECCAEIYPDITYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECG 247
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 61.3 bits (142), Expect = 8e-09
Identities = 51/236 (21%), Positives = 98/236 (41%), Gaps = 6/236 (2%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L+ L Y P +V+ + I + V E + + + + +Q W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 209 FLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
+ SI++ E IWRPD YN +T K + G + ++
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNADGDF-AVTHLTKA-HLFHDGRVQWTPPAIY 157
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQ--LVYQWQNSQSVNFVPGMTLSQFDLISF 325
K+ C +++ FP D+Q+C + GS+ Y + LV ++F D +
Sbjct: 158 KSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVDAVG- 216
Query: 326 PYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y + + + +F ++R ++ I + +PC+LI L+ + F++ E G
Sbjct: 217 TYNTRKYECCAEIYPDITYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECG 272
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 61.3 bits (142), Expect = 8e-09
Identities = 51/236 (21%), Positives = 98/236 (41%), Gaps = 6/236 (2%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L+ L Y P +V+ + I + V E + + + + +Q W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 209 FLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
+ SI++ E IWRPD YN +T K + G + ++
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNADGDF-AVTHLTKA-HLFHDGRVQWTPPAIY 157
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQ--LVYQWQNSQSVNFVPGMTLSQFDLISF 325
K+ C +++ FP D+Q+C + GS+ Y + LV ++F D +
Sbjct: 158 KSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVDAVG- 216
Query: 326 PYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y + + + +F ++R ++ I + +PC+LI L+ + F++ E G
Sbjct: 217 TYNTRKYECCAEIYPDITYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECG 272
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 61.3 bits (142), Expect = 8e-09
Identities = 51/236 (21%), Positives = 98/236 (41%), Gaps = 6/236 (2%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L+ L Y P +V+ + I + V E + + + + +Q W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 209 FLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
+ SI++ E IWRPD YN +T K + G + ++
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNADGDF-AVTHLTKA-HLFHDGRVQWTPPAIY 157
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQ--LVYQWQNSQSVNFVPGMTLSQFDLISF 325
K+ C +++ FP D+Q+C + GS+ Y + LV ++F D +
Sbjct: 158 KSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVDAVG- 216
Query: 326 PYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y + + + +F ++R ++ I + +PC+LI L+ + F++ E G
Sbjct: 217 TYNTRKYECCAEIYPDITYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECG 272
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 61.3 bits (142), Expect = 8e-09
Identities = 51/236 (21%), Positives = 98/236 (41%), Gaps = 6/236 (2%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L+ L Y P +V+ + I + V E + + + + +Q W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 209 FLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
+ SI++ E IWRPD YN +T K + G + ++
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNADGDF-AVTHLTKA-HLFHDGRVQWTPPAIY 157
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQ--LVYQWQNSQSVNFVPGMTLSQFDLISF 325
K+ C +++ FP D+Q+C + GS+ Y + LV ++F D +
Sbjct: 158 KSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVDAVG- 216
Query: 326 PYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y + + + +F ++R ++ I + +PC+LI L+ + F++ E G
Sbjct: 217 TYNTRKYECCAEIYPDITYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECG 272
>AL121827-20|CAC36119.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 61.3 bits (142), Expect = 8e-09
Identities = 51/236 (21%), Positives = 98/236 (41%), Gaps = 6/236 (2%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L+ L Y P +V+ + I + V E + + + + +Q W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 209 FLGPIRSLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
+ SI++ E IWRPD YN +T K + G + ++
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNADGDF-AVTHLTKA-HLFHDGRVQWTPPAIY 157
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQ--LVYQWQNSQSVNFVPGMTLSQFDLISF 325
K+ C +++ FP D+Q+C + GS+ Y + LV ++F D +
Sbjct: 158 KSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVDAVG- 216
Query: 326 PYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y + + + +F ++R ++ I + +PC+LI L+ + F++ E G
Sbjct: 217 TYNTRKYECCAEIYPDITYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECG 272
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 60.9 bits (141), Expect = 1e-08
Identities = 50/239 (20%), Positives = 105/239 (43%), Gaps = 12/239 (5%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+ ++L + Y P +V+ + I + V E + + + + +Q W D +L
Sbjct: 62 LFKHLFRGYNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLR 121
Query: 209 F----LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
+ G I SL + +M IW PD YN +T K S G + +
Sbjct: 122 WNPADFGNITSLRVPSEM---IWIPDIVLYNNADGEF-AVTHMTKAHLFST-GTVHWVPP 176
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLIS 324
K+ C +++ FP D+Q+C + GS+ Y ++ + Q Q+V+ ++ +++
Sbjct: 177 AIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLE-QMEQTVDLKDYWESGEWAIVN 235
Query: 325 F--PYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y + + + + +F ++R ++ I + +PC+LI L+ + F++ + G
Sbjct: 236 ATGTYNSKKYDCCAEIYPDVTYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCG 294
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 60.9 bits (141), Expect = 1e-08
Identities = 50/239 (20%), Positives = 105/239 (43%), Gaps = 12/239 (5%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+ ++L + Y P +V+ + I + V E + + + + +Q W D +L
Sbjct: 62 LFKHLFRGYNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLR 121
Query: 209 F----LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
+ G I SL + +M IW PD YN +T K S G + +
Sbjct: 122 WNPADFGNITSLRVPSEM---IWIPDIVLYNNADGEF-AVTHMTKAHLFST-GTVHWVPP 176
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLIS 324
K+ C +++ FP D+Q+C + GS+ Y ++ + Q Q+V+ ++ +++
Sbjct: 177 AIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLE-QMEQTVDLKDYWESGEWAIVN 235
Query: 325 F--PYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
Y + + + + +F ++R ++ I + +PC+LI L+ + F++ + G
Sbjct: 236 ATGTYNSKKYDCCAEIYPDVTYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCG 294
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 59.3 bits (137), Expect = 3e-08
Identities = 53/246 (21%), Positives = 104/246 (42%), Gaps = 18/246 (7%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+ +L NY ++ P V + + + + E + ++ + RQ W D L
Sbjct: 33 LFRDLFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTLYLWIRQEWTDAYLR 92
Query: 209 F----LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
+ G + ++ + + +WRPD YN + N +LR G + +
Sbjct: 93 WDPNAYGGLDAIRIPSSL---VWRPDIVLYNKADAQPPGSASTNVVLR--HDGAVRWDAP 147
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQS--VNFVPGMTLSQFDL 322
++ C +++ FP D Q C L GS+ + QL + + + + +FV + ++ +
Sbjct: 148 AITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLDVRPRGAAASLADFVENV---EWRV 204
Query: 323 ISFPYRNFTFTRREGDFSVLQVSFN--LKRHTGYFLIQVYVPCILIVVLSWVSFWIHREV 380
+ P R T V+F L+R ++ + +PC+LI +L+ ++F H
Sbjct: 205 LGMPARRRVLTYGCCSEPYPDVTFTLLLRRRAAAYVCNLLLPCVLISLLAPLAF--HLPA 262
Query: 381 GSGEIV 386
SGE V
Sbjct: 263 DSGEKV 268
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 59.3 bits (137), Expect = 3e-08
Identities = 53/246 (21%), Positives = 104/246 (42%), Gaps = 18/246 (7%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+ +L NY ++ P V + + + + E + ++ + RQ W D L
Sbjct: 33 LFRDLFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTLYLWIRQEWTDAYLR 92
Query: 209 F----LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
+ G + ++ + + +WRPD YN + N +LR G + +
Sbjct: 93 WDPNAYGGLDAIRIPSSL---VWRPDIVLYNKADAQPPGSASTNVVLR--HDGAVRWDAP 147
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQS--VNFVPGMTLSQFDL 322
++ C +++ FP D Q C L GS+ + QL + + + + +FV + ++ +
Sbjct: 148 AITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLDVRPRGAAASLADFVENV---EWRV 204
Query: 323 ISFPYRNFTFTRREGDFSVLQVSFN--LKRHTGYFLIQVYVPCILIVVLSWVSFWIHREV 380
+ P R T V+F L+R ++ + +PC+LI +L+ ++F H
Sbjct: 205 LGMPARRRVLTYGCCSEPYPDVTFTLLLRRRAAAYVCNLLLPCVLISLLAPLAF--HLPA 262
Query: 381 GSGEIV 386
SGE V
Sbjct: 263 DSGEKV 268
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 59.3 bits (137), Expect = 3e-08
Identities = 53/246 (21%), Positives = 104/246 (42%), Gaps = 18/246 (7%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+ +L NY ++ P V + + + + E + ++ + RQ W D L
Sbjct: 33 LFRDLFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTLYLWIRQEWTDAYLR 92
Query: 209 F----LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
+ G + ++ + + +WRPD YN + N +LR G + +
Sbjct: 93 WDPNAYGGLDAIRIPSSL---VWRPDIVLYNKADAQPPGSASTNVVLR--HDGAVRWDAP 147
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQS--VNFVPGMTLSQFDL 322
++ C +++ FP D Q C L GS+ + QL + + + + +FV + ++ +
Sbjct: 148 AITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLDVRPRGAAASLADFVENV---EWRV 204
Query: 323 ISFPYRNFTFTRREGDFSVLQVSFN--LKRHTGYFLIQVYVPCILIVVLSWVSFWIHREV 380
+ P R T V+F L+R ++ + +PC+LI +L+ ++F H
Sbjct: 205 LGMPARRRVLTYGCCSEPYPDVTFTLLLRRRAAAYVCNLLLPCVLISLLAPLAF--HLPA 262
Query: 381 GSGEIV 386
SGE V
Sbjct: 263 DSGEKV 268
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 59.3 bits (137), Expect = 3e-08
Identities = 53/246 (21%), Positives = 104/246 (42%), Gaps = 18/246 (7%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+ +L NY ++ P V + + + + E + ++ + RQ W D L
Sbjct: 33 LFRDLFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTLYLWIRQEWTDAYLR 92
Query: 209 F----LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMR 264
+ G + ++ + + +WRPD YN + N +LR G + +
Sbjct: 93 WDPNAYGGLDAIRIPSSL---VWRPDIVLYNKADAQPPGSASTNVVLR--HDGAVRWDAP 147
Query: 265 LTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQS--VNFVPGMTLSQFDL 322
++ C +++ FP D Q C L GS+ + QL + + + + +FV + ++ +
Sbjct: 148 AITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLDVRPRGAAASLADFVENV---EWRV 204
Query: 323 ISFPYRNFTFTRREGDFSVLQVSFN--LKRHTGYFLIQVYVPCILIVVLSWVSFWIHREV 380
+ P R T V+F L+R ++ + +PC+LI +L+ ++F H
Sbjct: 205 LGMPARRRVLTYGCCSEPYPDVTFTLLLRRRAAAYVCNLLLPCVLISLLAPLAF--HLPA 262
Query: 381 GSGEIV 386
SGE V
Sbjct: 263 DSGEKV 268
>AF018157-1|AAC39918.1| 219|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 219
Score = 57.6 bits (133), Expect = 1e-07
Identities = 21/42 (50%), Positives = 32/42 (76%)
Query: 346 FNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVGSGEIVI 387
F+L+R GY+LIQ+Y+P +LIV+LSWVSFWI+ + + +
Sbjct: 2 FHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVAL 43
Score = 36.3 bits (80), Expect = 0.27
Identities = 13/30 (43%), Positives = 19/30 (63%)
Query: 491 INSVSHIDRAARVLFPASFALLNLFYWMIY 520
I+ ID +R FP +F + N+FYW+IY
Sbjct: 177 IDRAKKIDTISRACFPLAFLIFNIFYWVIY 206
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 57.2 bits (132), Expect = 1e-07
Identities = 49/246 (19%), Positives = 110/246 (44%), Gaps = 13/246 (5%)
Query: 141 AVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQ 200
+++K+ S+L++L ++YE P ++ + I + V E + + + + +Q
Sbjct: 42 SIAKHEDSLLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQ 101
Query: 201 YWRDTRLSFLGPIRSLSLSIKML--ERIWRPDTYFYN---GKHSYVHTITVPNKLLRISQ 255
W D +L + P + + + + +W PD ++ G+ T TV I
Sbjct: 102 EWIDVKLRW-NPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTV------IRY 154
Query: 256 HGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGM 315
+G + ++ K+ C +++ FP D Q+C + GS+ Y Q+ ++ Q V+
Sbjct: 155 NGTVTWTPPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILED-QDVDKRDFF 213
Query: 316 TLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFW 375
+++++S T + + SF +KR ++ + + +PCI + L+ + F+
Sbjct: 214 DNGEWEIVSATGSKGNRTDSCCWYPYVTYSFVIKRLPLFYTLFLIIPCIGLSFLTVLVFY 273
Query: 376 IHREVG 381
+ G
Sbjct: 274 LPSNEG 279
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 57.2 bits (132), Expect = 1e-07
Identities = 49/246 (19%), Positives = 110/246 (44%), Gaps = 13/246 (5%)
Query: 141 AVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQ 200
+++K+ S+L++L ++YE P ++ + I + V E + + + + +Q
Sbjct: 42 SIAKHEDSLLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQ 101
Query: 201 YWRDTRLSFLGPIRSLSLSIKML--ERIWRPDTYFYN---GKHSYVHTITVPNKLLRISQ 255
W D +L + P + + + + +W PD ++ G+ T TV I
Sbjct: 102 EWIDVKLRW-NPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTV------IRY 154
Query: 256 HGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGM 315
+G + ++ K+ C +++ FP D Q+C + GS+ Y Q+ ++ Q V+
Sbjct: 155 NGTVTWTPPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILED-QDVDKRDFF 213
Query: 316 TLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFW 375
+++++S T + + SF +KR ++ + + +PCI + L+ + F+
Sbjct: 214 DNGEWEIVSATGSKGNRTDSCCWYPYVTYSFVIKRLPLFYTLFLIIPCIGLSFLTVLVFY 273
Query: 376 IHREVG 381
+ G
Sbjct: 274 LPSNEG 279
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 57.2 bits (132), Expect = 1e-07
Identities = 49/246 (19%), Positives = 110/246 (44%), Gaps = 13/246 (5%)
Query: 141 AVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQ 200
+++K+ S+L++L ++YE P ++ + I + V E + + + + +Q
Sbjct: 42 SIAKHEDSLLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQ 101
Query: 201 YWRDTRLSFLGPIRSLSLSIKML--ERIWRPDTYFYN---GKHSYVHTITVPNKLLRISQ 255
W D +L + P + + + + +W PD ++ G+ T TV I
Sbjct: 102 EWIDVKLRW-NPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTV------IRY 154
Query: 256 HGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGM 315
+G + ++ K+ C +++ FP D Q+C + GS+ Y Q+ ++ Q V+
Sbjct: 155 NGTVTWTPPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILED-QDVDKRDFF 213
Query: 316 TLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFW 375
+++++S T + + SF +KR ++ + + +PCI + L+ + F+
Sbjct: 214 DNGEWEIVSATGSKGNRTDSCCWYPYVTYSFVIKRLPLFYTLFLIIPCIGLSFLTVLVFY 273
Query: 376 IHREVG 381
+ G
Sbjct: 274 LPSNEG 279
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 57.2 bits (132), Expect = 1e-07
Identities = 49/246 (19%), Positives = 110/246 (44%), Gaps = 13/246 (5%)
Query: 141 AVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQ 200
+++K+ S+L++L ++YE P ++ + I + V E + + + + +Q
Sbjct: 42 SIAKHEDSLLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQ 101
Query: 201 YWRDTRLSFLGPIRSLSLSIKML--ERIWRPDTYFYN---GKHSYVHTITVPNKLLRISQ 255
W D +L + P + + + + +W PD ++ G+ T TV I
Sbjct: 102 EWIDVKLRW-NPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTV------IRY 154
Query: 256 HGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGM 315
+G + ++ K+ C +++ FP D Q+C + GS+ Y Q+ ++ Q V+
Sbjct: 155 NGTVTWTPPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILED-QDVDKRDFF 213
Query: 316 TLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFW 375
+++++S T + + SF +KR ++ + + +PCI + L+ + F+
Sbjct: 214 DNGEWEIVSATGSKGNRTDSCCWYPYVTYSFVIKRLPLFYTLFLIIPCIGLSFLTVLVFY 273
Query: 376 IHREVG 381
+ G
Sbjct: 274 LPSNEG 279
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 56.8 bits (131), Expect = 2e-07
Identities = 47/230 (20%), Positives = 104/230 (45%), Gaps = 8/230 (3%)
Query: 155 KNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIR 214
K Y+ P V + I + V E + + + + +Q W D +L +
Sbjct: 3 KGYQKWVRPVLHSNDTIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDDY 62
Query: 215 SLSLSIKM-LERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPM 273
SIK+ E +W PD + ++ K++ + +G ++++ + K+ C M
Sbjct: 63 GGIHSIKVPSESLWLPDIVLFENADGRFEG-SLMTKVI-VKSNGTVVWTPPASYKSSCTM 120
Query: 274 ELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRNFTFT 333
++ FP DRQ+C + GS+ Y + N ++V+ ++++++ +
Sbjct: 121 DVTFFPFDRQNCSMKFGSWTYDGTMVDLILIN-ENVDRKDFFDNGEWEILN--AKGMKGN 177
Query: 334 RREGDFS--VLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREVG 381
RR+G +S + SF L+R ++ + + +PC+ + L+ + F++ + G
Sbjct: 178 RRDGVYSYPFITYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEG 227
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 55.2 bits (127), Expect = 5e-07
Identities = 49/246 (19%), Positives = 109/246 (44%), Gaps = 13/246 (5%)
Query: 141 AVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQ 200
+++K+ S+L++L ++YE P ++ + I + V E + + + + +Q
Sbjct: 42 SIAKHEDSLLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQ 101
Query: 201 YWRDTRLSFLGPIRSLSLSIKML--ERIWRPDTYFYN---GKHSYVHTITVPNKLLRISQ 255
W D +L + P + + + + W PD ++ G+ T TV I
Sbjct: 102 EWIDVKLRW-NPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTV------IRY 154
Query: 256 HGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGM 315
+G + ++ K+ C +++ FP D Q+C + GS+ Y Q+ ++ Q V+
Sbjct: 155 NGTVTWTPPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILED-QDVDKRDFF 213
Query: 316 TLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFW 375
+++++S T + + SF +KR ++ + + +PCI + L+ + F+
Sbjct: 214 DNGEWEIVSATGSKGNRTDSCCWYPYVTYSFVIKRLPLFYTLFLIIPCIGLSFLTVLVFY 273
Query: 376 IHREVG 381
+ G
Sbjct: 274 LPSNEG 279
>BC101348-1|AAI01349.1| 412|Homo sapiens CHRNA7 (cholinergic
receptor, nicotinic, alpha 7, exons 5-10) and FAM7A
(family protein.
Length = 412
Score = 54.0 bits (124), Expect = 1e-06
Identities = 31/131 (23%), Positives = 62/131 (47%), Gaps = 5/131 (3%)
Query: 253 ISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFV 312
++ G Y K+ C +++R FP D Q C L GS++Y L Q Q + ++
Sbjct: 42 VNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYI 101
Query: 313 PGMTLSQFDLISFPYRNFT--FTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLS 370
P ++DL+ P + + + + + + ++R T Y+ + + +PC+LI L+
Sbjct: 102 PN---GEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALA 158
Query: 371 WVSFWIHREVG 381
+ F + + G
Sbjct: 159 LLVFLLPADSG 169
>BC101347-1|AAI01348.1| 412|Homo sapiens CHRNA7 (cholinergic
receptor, nicotinic, alpha 7, exons 5-10) and FAM7A
(family protein.
Length = 412
Score = 54.0 bits (124), Expect = 1e-06
Identities = 31/131 (23%), Positives = 62/131 (47%), Gaps = 5/131 (3%)
Query: 253 ISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFV 312
++ G Y K+ C +++R FP D Q C L GS++Y L Q Q + ++
Sbjct: 42 VNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYI 101
Query: 313 PGMTLSQFDLISFPYRNFT--FTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLS 370
P ++DL+ P + + + + + + ++R T Y+ + + +PC+LI L+
Sbjct: 102 PN---GEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALA 158
Query: 371 WVSFWIHREVG 381
+ F + + G
Sbjct: 159 LLVFLLPADSG 169
>BC101346-1|AAI01347.1| 412|Homo sapiens CHRNA7 (cholinergic
receptor, nicotinic, alpha 7, exons 5-10) and FAM7A
(family protein.
Length = 412
Score = 54.0 bits (124), Expect = 1e-06
Identities = 31/131 (23%), Positives = 62/131 (47%), Gaps = 5/131 (3%)
Query: 253 ISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFV 312
++ G Y K+ C +++R FP D Q C L GS++Y L Q Q + ++
Sbjct: 42 VNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYI 101
Query: 313 PGMTLSQFDLISFPYRNFT--FTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLS 370
P ++DL+ P + + + + + + ++R T Y+ + + +PC+LI L+
Sbjct: 102 PN---GEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALA 158
Query: 371 WVSFWIHREVG 381
+ F + + G
Sbjct: 159 LLVFLLPADSG 169
>AF169255-1|AAF03691.1| 441|Homo sapiens 5-hydroxytryptamine 3
receptor B subunit protein.
Length = 441
Score = 54.0 bits (124), Expect = 1e-06
Identities = 47/234 (20%), Positives = 100/234 (42%), Gaps = 15/234 (6%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF- 209
+ LL+ Y P + T V ++ + ++ V + ++++ W D LS+
Sbjct: 37 KQLLQKYHKEVRPVYNWTKATTVYLDLFVHAILDVDAENQILKTSVWYQEVWNDEFLSWN 96
Query: 210 ---LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPN-KLLRISQHGDILYSMRL 265
IR +SL L IW PD + +V P+ + ++ G I +
Sbjct: 97 SSMFDEIREISLP---LSAIWAPDIII----NEFVDIERYPDLPYVYVNSSGTIENYKPI 149
Query: 266 TIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNS-QSVNFVPGMTL--SQFDL 322
+ + C +E FP D Q+C L S ++ + + + S + + L S+++L
Sbjct: 150 QVVSACSLETYAFPFDVQNCSLTFKSILHTVEDVDLAFLRSPEDIQHDKKAFLNDSEWEL 209
Query: 323 ISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
+S G F+ +Q + ++RH +++ + +P I ++++ SF++
Sbjct: 210 LSVSSTYSILQSSAGGFAQIQFNVVMRRHPLVYVVSLLIPSIFLMLVDLGSFYL 263
>AF080582-1|AAD12242.1| 441|Homo sapiens 5-hydroxytryptamine 3
receptor B subunit precursor protein.
Length = 441
Score = 54.0 bits (124), Expect = 1e-06
Identities = 47/234 (20%), Positives = 100/234 (42%), Gaps = 15/234 (6%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF- 209
+ LL+ Y P + T V ++ + ++ V + ++++ W D LS+
Sbjct: 37 KQLLQKYHKEVRPVYNWTKATTVYLDLFVHAILDVDAENQILKTSVWYQEVWNDEFLSWN 96
Query: 210 ---LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPN-KLLRISQHGDILYSMRL 265
IR +SL L IW PD + +V P+ + ++ G I +
Sbjct: 97 SSMFDEIREISLP---LSAIWAPDIII----NEFVDIERYPDLPYVYVNSSGTIENYKPI 149
Query: 266 TIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNS-QSVNFVPGMTL--SQFDL 322
+ + C +E FP D Q+C L S ++ + + + S + + L S+++L
Sbjct: 150 QVVSACSLETYAFPFDVQNCSLTFKSILHTVEDVDLAFLRSPEDIQHDKKAFLNDSEWEL 209
Query: 323 ISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
+S G F+ +Q + ++RH +++ + +P I ++++ SF++
Sbjct: 210 LSVSSTYSILQSSAGGFAQIQFNVVMRRHPLVYVVSLLIPSIFLMLVDLGSFYL 263
>AM293589-1|CAL25321.1| 430|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit B protein.
Length = 430
Score = 53.6 bits (123), Expect = 2e-06
Identities = 47/234 (20%), Positives = 100/234 (42%), Gaps = 15/234 (6%)
Query: 151 ENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF- 209
+ LL+ Y P + T V ++ + ++ V + ++++ W D LS+
Sbjct: 26 KQLLQKYHKEVRPVYNWTKATTVYLDLFVHAILDVDAENQILKTSVWYQEVWNDEFLSWN 85
Query: 210 ---LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPN-KLLRISQHGDILYSMRL 265
IR +SL L IW PD + +V P+ + ++ G I +
Sbjct: 86 SSMFDEIREISLP---LSAIWAPDIII----NEFVDIERSPDLPYVYVNSSGTIENYKPI 138
Query: 266 TIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNS-QSVNFVPGMTL--SQFDL 322
+ + C +E FP D Q+C L S ++ + + + S + + L S+++L
Sbjct: 139 QVVSACSLETYAFPFDVQNCSLTFKSILHTVEDVDLAFLRSPEDIQHDKKAFLNDSEWEL 198
Query: 323 ISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWI 376
+S G F+ +Q + ++RH +++ + +P I ++++ SF++
Sbjct: 199 LSVSSTYSILQSSAGGFAQIQFNVVMRRHPLVYVVSLLIPSIFLMLVDLGSFYL 252
>AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor
protein.
Length = 238
Score = 52.4 bits (120), Expect = 4e-06
Identities = 38/149 (25%), Positives = 65/149 (43%), Gaps = 12/149 (8%)
Query: 153 LLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF--- 209
LL NY P PT V ++++ ++ V E + + ++RQYW D L +
Sbjct: 41 LLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPE 100
Query: 210 -LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPN-KLLRISQHGDILYSMRLTI 267
I LS+ + IW PD + +V PN + I G++ L +
Sbjct: 101 DFDNITKLSIP---TDSIWVPDILI----NEFVDVGKSPNIPYVYIRHQGEVQNYKPLQV 153
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSN 296
C +++ NFP D Q+C L S+ +++
Sbjct: 154 VTACSLDIYNFPFDVQNCSLTFTSWLHTS 182
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 48.0 bits (109), Expect = 8e-05
Identities = 40/154 (25%), Positives = 63/154 (40%), Gaps = 7/154 (4%)
Query: 152 NLLKNYENS-QLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL 210
NL K + S Q+P +G P +V + + ++ V L S R W DTRL++
Sbjct: 40 NLSKKVQESIQIPNNGSA-PLLVDVRVFVSNVFNVDILRYTMSSMLLLRLSWLDTRLAWN 98
Query: 211 GPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAK 270
E +W P +V + R+ Q G + ++ LT +
Sbjct: 99 TSAHPRHAITLPWESLWTPRLTILEAL--WVDWRD-QSPQARVDQDGHVKLNLALTTETN 155
Query: 271 CPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQ 304
C EL +FP D +C L YA SN + ++Q
Sbjct: 156 CNFELLHFPRDHSNCS--LSFYALSNTAMELEFQ 187
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 48.0 bits (109), Expect = 8e-05
Identities = 40/154 (25%), Positives = 63/154 (40%), Gaps = 7/154 (4%)
Query: 152 NLLKNYENS-QLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL 210
NL K + S Q+P +G P +V + + ++ V L S R W DTRL++
Sbjct: 40 NLSKKVQESIQIPNNGSA-PLLVDVRVFVSNVFNVDILRYTMSSMLLLRLSWLDTRLAWN 98
Query: 211 GPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAK 270
E +W P +V + R+ Q G + ++ LT +
Sbjct: 99 TSAHPRHAITLPWESLWTPRLTILEAL--WVDWRD-QSPQARVDQDGHVKLNLALTTETN 155
Query: 271 CPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQ 304
C EL +FP D +C L YA SN + ++Q
Sbjct: 156 CNFELLHFPRDHSNCS--LSFYALSNTAMELEFQ 187
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 46.4 bits (105), Expect = 3e-04
Identities = 36/168 (21%), Positives = 71/168 (42%), Gaps = 7/168 (4%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L +L++NY+ + P V + + ++ ++E + + + + W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 209 FLGPIRSLSLSIKMLER--IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLT 266
+ P L + + +WRPD N N L +S G I +
Sbjct: 92 W-DPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVFEVALYCNVL--VSPDGCIYWLPPAI 148
Query: 267 IKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQ--WQNSQSVNFV 312
++ C + + FP D Q+C LI S YS ++ Q ++ Q++ ++
Sbjct: 149 FRSACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQLSQEDGQTIEWI 196
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 46.4 bits (105), Expect = 3e-04
Identities = 36/168 (21%), Positives = 71/168 (42%), Gaps = 7/168 (4%)
Query: 149 VLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLS 208
+L +L++NY+ + P V + + ++ ++E + + + + W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 209 FLGPIRSLSLSIKMLER--IWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLT 266
+ P L + + +WRPD N N L +S G I +
Sbjct: 92 W-DPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVFEVALYCNVL--VSPDGCIYWLPPAI 148
Query: 267 IKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQ--WQNSQSVNFV 312
++ C + + FP D Q+C LI S YS ++ Q ++ Q++ ++
Sbjct: 149 FRSACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQLSQEDGQTIEWI 196
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 46.0 bits (104), Expect = 3e-04
Identities = 39/146 (26%), Positives = 59/146 (40%), Gaps = 7/146 (4%)
Query: 152 NLLKNYENS-QLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL 210
NL K + S Q+P +G P +V + + ++ V L S R W DTRL++
Sbjct: 41 NLSKKVQESIQIPNNGSA-PLLVDVRVFVSNVFNVDILRYTMSSMLLLRLSWLDTRLAWN 99
Query: 211 GPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAK 270
E +W P +V + R+ Q G + ++ LT +
Sbjct: 100 TSAHPRHAITLPWESLWTPRLTILEAL--WVDWRD-QSPQARVDQDGHVKLNLALTTETN 156
Query: 271 CPMELRNFPMDRQSCPLILGSYAYSN 296
C EL +FP D +C L YA SN
Sbjct: 157 CNFELLHFPRDHSNCS--LSFYALSN 180
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 46.0 bits (104), Expect = 3e-04
Identities = 39/154 (25%), Positives = 62/154 (40%), Gaps = 7/154 (4%)
Query: 152 NLLKNYENS-QLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFL 210
NL K + S Q+P +G P +V + + ++ V L S R W DTRL++
Sbjct: 40 NLSKKVQESIQIPNNGSA-PLLVDVRVFVSNVFNVDILRYTMSSMLLLRLSWLDTRLAWN 98
Query: 211 GPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAK 270
E +W P +V + R+ Q G + ++ L +
Sbjct: 99 TSAHPRHAITLPWESLWTPRLTILEAL--WVDWRD-QSPQARVDQDGHVKLNLALATETN 155
Query: 271 CPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQ 304
C EL +FP D +C L YA SN + ++Q
Sbjct: 156 CNFELLHFPRDHSNCS--LSFYALSNTAMELEFQ 187
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 45.6 bits (103), Expect = 4e-04
Identities = 46/252 (18%), Positives = 107/252 (42%), Gaps = 22/252 (8%)
Query: 152 NLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF-- 209
+L NY+ P + + + ++ ++E + + + W+D RL++
Sbjct: 30 HLFNNYDPGSRPVREPEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSK 89
Query: 210 --LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
G I +L + ++ +W P+ N N L + + G + +
Sbjct: 90 DDFGGIETLRVPSEL---VWLPEIVLENNIDGQFGVAYDANVL--VYEGGSVTWLPPAIY 144
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW---QNSQSVNFVPGMTLSQFD--- 321
++ C +E+ FP D Q+C LI S Y+ +++ + + + +++N + T + +
Sbjct: 145 RSVCAVEVTYFPFDWQNCSLIFRSQTYNAEEVEFTFAVDNDGKTINKIDIDTEAYTENGE 204
Query: 322 -LISF-----PYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFW 375
I F + T G+ V+ S ++R +++I + VPC+LI L ++++
Sbjct: 205 WAIDFCPGVIRRHHGGATDGPGETDVI-YSLIIRRKPLFYVINIIVPCVLISGLVLLAYF 263
Query: 376 IHREVGSGEIVI 387
+ + G + +
Sbjct: 264 LPAQAGGQKCTV 275
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 45.6 bits (103), Expect = 4e-04
Identities = 46/252 (18%), Positives = 107/252 (42%), Gaps = 22/252 (8%)
Query: 152 NLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSF-- 209
+L NY+ P + + + ++ ++E + + + W+D RL++
Sbjct: 30 HLFNNYDPGSRPVREPEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSK 89
Query: 210 --LGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTI 267
G I +L + ++ +W P+ N N L + + G + +
Sbjct: 90 DDFGGIETLRVPSEL---VWLPEIVLENNIDGQFGVAYDANVL--VYEGGSVTWLPPAIY 144
Query: 268 KAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQW---QNSQSVNFVPGMTLSQFD--- 321
++ C +E+ FP D Q+C LI S Y+ +++ + + + +++N + T + +
Sbjct: 145 RSVCAVEVTYFPFDWQNCSLIFRSQTYNAEEVEFTFAVDNDGKTINKIDIDTEAYTENGE 204
Query: 322 -LISF-----PYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFW 375
I F + T G+ V+ S ++R +++I + VPC+LI L ++++
Sbjct: 205 WAIDFCPGVIRRHHGGATDGPGETDVI-YSLIIRRKPLFYVINIIVPCVLISGLVLLAYF 263
Query: 376 IHREVGSGEIVI 387
+ + G + +
Sbjct: 264 LPAQAGGQKCTV 275
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 44.4 bits (100), Expect = 0.001
Identities = 46/242 (19%), Positives = 96/242 (39%), Gaps = 17/242 (7%)
Query: 155 KNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGP-I 213
K Y P K V + + ++ + E++ + + + W D RL +
Sbjct: 36 KGYNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEF 95
Query: 214 RSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPM 273
++S+ + +W P+ N N L + +G + + ++ CP+
Sbjct: 96 GNISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVL--VYHYGFVYWLPPAIFRSSCPI 153
Query: 274 ELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFV----------PGMTLS-QFDL 322
+ FP D Q+C L S Y+ +++ + N G T + ++++
Sbjct: 154 SVTYFPFDWQNCSLKFSSLKYTAKEITLSLKQDAKENRTYPVEWIIIDPEGFTENGEWEI 213
Query: 323 ISFPYRNFTFTRREGDFSVLQ-VSFNL--KRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
+ P R R D Q ++F L +R +++I + VPC+LI + + F++ +
Sbjct: 214 VHRPARVNVDPRAPLDSPSRQDITFYLIIRRKPLFYIINILVPCVLISFMVNLVFYLPAD 273
Query: 380 VG 381
G
Sbjct: 274 SG 275
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 44.4 bits (100), Expect = 0.001
Identities = 46/242 (19%), Positives = 96/242 (39%), Gaps = 17/242 (7%)
Query: 155 KNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGP-I 213
K Y P K V + + ++ + E++ + + + W D RL +
Sbjct: 36 KGYNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEF 95
Query: 214 RSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPM 273
++S+ + +W P+ N N L + +G + + ++ CP+
Sbjct: 96 GNISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVL--VYHYGFVYWLPPAIFRSSCPI 153
Query: 274 ELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFV----------PGMTLS-QFDL 322
+ FP D Q+C L S Y+ +++ + N G T + ++++
Sbjct: 154 SVTYFPFDWQNCSLKFSSLKYTAKEITLSLKQDAKENRTYPVEWIIIDPEGFTENGEWEI 213
Query: 323 ISFPYRNFTFTRREGDFSVLQ-VSFNL--KRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
+ P R R D Q ++F L +R +++I + VPC+LI + + F++ +
Sbjct: 214 VHRPARVNVDPRAPLDSPSRQDITFYLIIRRKPLFYIINILVPCVLISFMVNLVFYLPAD 273
Query: 380 VG 381
G
Sbjct: 274 SG 275
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 44.4 bits (100), Expect = 0.001
Identities = 46/242 (19%), Positives = 96/242 (39%), Gaps = 17/242 (7%)
Query: 155 KNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGP-I 213
K Y P K V + + ++ + E++ + + + W D RL +
Sbjct: 36 KGYNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEF 95
Query: 214 RSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPM 273
++S+ + +W P+ N N L + +G + + ++ CP+
Sbjct: 96 GNISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVL--VYHYGFVYWLPPAIFRSSCPI 153
Query: 274 ELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFV----------PGMTLS-QFDL 322
+ FP D Q+C L S Y+ +++ + N G T + ++++
Sbjct: 154 SVTYFPFDWQNCSLKFSSLKYTAKEITLSLKQDAKENRTYPVEWIIIDPEGFTENGEWEI 213
Query: 323 ISFPYRNFTFTRREGDFSVLQ-VSFNL--KRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
+ P R R D Q ++F L +R +++I + VPC+LI + + F++ +
Sbjct: 214 VHRPARVNVDPRAPLDSPSRQDITFYLIIRRKPLFYIINILVPCVLISFMVNLVFYLPAD 273
Query: 380 VG 381
G
Sbjct: 274 SG 275
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 44.4 bits (100), Expect = 0.001
Identities = 46/242 (19%), Positives = 96/242 (39%), Gaps = 17/242 (7%)
Query: 155 KNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGP-I 213
K Y P K V + + ++ + E++ + + + W D RL +
Sbjct: 36 KGYNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEF 95
Query: 214 RSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPM 273
++S+ + +W P+ N N L + +G + + ++ CP+
Sbjct: 96 GNISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVL--VYHYGFVYWLPPAIFRSSCPI 153
Query: 274 ELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFV----------PGMTLS-QFDL 322
+ FP D Q+C L S Y+ +++ + N G T + ++++
Sbjct: 154 SVTYFPFDWQNCSLKFSSLKYTAKEITLSLKQDAKENRTYPVEWIIIDPEGFTENGEWEI 213
Query: 323 ISFPYRNFTFTRREGDFSVLQ-VSFNL--KRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
+ P R R D Q ++F L +R +++I + VPC+LI + + F++ +
Sbjct: 214 VHRPARVNVDPRAPLDSPSRQDITFYLIIRRKPLFYIINILVPCVLISFMVNLVFYLPAD 273
Query: 380 VG 381
G
Sbjct: 274 SG 275
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 43.6 bits (98), Expect = 0.002
Identities = 31/164 (18%), Positives = 68/164 (41%), Gaps = 11/164 (6%)
Query: 222 MLERIWRPDTYFYNGKHSYVHTITVPNKLLR-ISQHGDILYSMRLTIKAKCPMELRNFPM 280
+ E +W PD + + P+ L IS G I Y + + + C +++ FP
Sbjct: 116 LAENLWLPDIFIVES----MDVDQTPSGLTAYISSEGRIKYDKPMRVTSICKLDIFYFPF 171
Query: 281 DRQSCPLILGSYAYSNQQLVY-----QWQNSQSVNFVPGMTLSQFDLISFPYRNFTFTRR 335
D+Q+C S+ Y+ ++ W+ + + V T +++L+ +
Sbjct: 172 DQQNCTFTFSSFLYTVDSMLLGMDKEVWEITDTSRKVI-QTQGEWELLGINKATPKMSMG 230
Query: 336 EGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
+ + ++R ++I + VP +V + +SF++ E
Sbjct: 231 NNLYDQIMFYVAIRRRPSLYIINLLVPSSFLVAIDALSFYLPAE 274
>AF053072-1|AAD19830.1| 74|Homo sapiens GABA subunit A receptor
alpha 6 precursor protein.
Length = 74
Score = 43.6 bits (98), Expect = 0.002
Identities = 20/47 (42%), Positives = 33/47 (70%), Gaps = 1/47 (2%)
Query: 143 SKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELD 189
S+N++ +L+NLL+ Y+N P G G T V+T+I + S GPVS+++
Sbjct: 29 SENVSRILDNLLEGYDNRLRPGFG-GAVTEVKTDIYVTSFGPVSDVE 74
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 43.2 bits (97), Expect = 0.002
Identities = 31/164 (18%), Positives = 68/164 (41%), Gaps = 11/164 (6%)
Query: 222 MLERIWRPDTYFYNGKHSYVHTITVPNKLLR-ISQHGDILYSMRLTIKAKCPMELRNFPM 280
+ E +W PD + + P+ L IS G I Y + + + C +++ FP
Sbjct: 116 LAENLWLPDIFIVES----MDVDQTPSGLTAYISSEGRIKYDKPMRVTSICNLDIFYFPF 171
Query: 281 DRQSCPLILGSYAYSNQQLVY-----QWQNSQSVNFVPGMTLSQFDLISFPYRNFTFTRR 335
D+Q+C S+ Y+ ++ W+ + + V T +++L+ +
Sbjct: 172 DQQNCTFTFSSFLYTVDSMLLGMDKEVWEITDTSRKVI-QTQGEWELLGINKATPKMSMG 230
Query: 336 EGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHRE 379
+ + ++R ++I + VP +V + +SF++ E
Sbjct: 231 NNLYDQIMFYVAIRRRPSLYIINLLVPSSFLVAIDALSFYLPAE 274
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 41.9 bits (94), Expect = 0.005
Identities = 27/136 (19%), Positives = 61/136 (44%), Gaps = 8/136 (5%)
Query: 253 ISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQ-----WQ-NS 306
+S G I Y + + + C +++ FP D+Q+C L S+ Y+ ++ W+
Sbjct: 159 VSNEGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITD 218
Query: 307 QSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILI 366
S N + T +++L+ +R + + ++R ++I + VP +
Sbjct: 219 ASRNIL--QTHGEWELLGLSKATAKLSRGGNLYDQIVFYVAIRRRPSLYVINLLVPSGFL 276
Query: 367 VVLSWVSFWIHREVGS 382
V + +SF++ + G+
Sbjct: 277 VAIDALSFYLPVKSGN 292
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 41.9 bits (94), Expect = 0.005
Identities = 27/136 (19%), Positives = 61/136 (44%), Gaps = 8/136 (5%)
Query: 253 ISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQ-----WQ-NS 306
+S G I Y + + + C +++ FP D+Q+C L S+ Y+ ++ W+
Sbjct: 159 VSNEGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITD 218
Query: 307 QSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILI 366
S N + T +++L+ +R + + ++R ++I + VP +
Sbjct: 219 ASRNIL--QTHGEWELLGLSKATAKLSRGGNLYDQIVFYVAIRRRPSLYVINLLVPSGFL 276
Query: 367 VVLSWVSFWIHREVGS 382
V + +SF++ + G+
Sbjct: 277 VAIDALSFYLPVKSGN 292
>BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein.
Length = 556
Score = 41.9 bits (94), Expect = 0.005
Identities = 27/127 (21%), Positives = 57/127 (44%), Gaps = 3/127 (2%)
Query: 257 GDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQ--LVYQWQNSQSVNFVPG 314
G + ++ K+ C +++ FP D+Q+C + GS+ Y + LV ++F
Sbjct: 76 GRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWES 135
Query: 315 MTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSF 374
D + Y + + + +F ++R ++ I + +PC+LI L+ + F
Sbjct: 136 GEWVIVDAVG-TYNTRKYECCAEIYPDITYAFVIRRLPLFYTINLIIPCLLISCLTVLVF 194
Query: 375 WIHREVG 381
++ E G
Sbjct: 195 YLPSECG 201
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 41.9 bits (94), Expect = 0.005
Identities = 27/136 (19%), Positives = 61/136 (44%), Gaps = 8/136 (5%)
Query: 253 ISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQ-----WQ-NS 306
+S G I Y + + + C +++ FP D+Q+C L S+ Y+ ++ W+
Sbjct: 144 VSNEGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITD 203
Query: 307 QSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILI 366
S N + T +++L+ +R + + ++R ++I + VP +
Sbjct: 204 ASRNIL--QTHGEWELLGLSKATAKLSRGGNLYDQIVFYVAIRRRPSLYVINLLVPSGFL 261
Query: 367 VVLSWVSFWIHREVGS 382
V + +SF++ + G+
Sbjct: 262 VAIDALSFYLPVKSGN 277
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 41.9 bits (94), Expect = 0.005
Identities = 27/136 (19%), Positives = 61/136 (44%), Gaps = 8/136 (5%)
Query: 253 ISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQ-----WQ-NS 306
+S G I Y + + + C +++ FP D+Q+C L S+ Y+ ++ W+
Sbjct: 129 VSNEGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITD 188
Query: 307 QSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILI 366
S N + T +++L+ +R + + ++R ++I + VP +
Sbjct: 189 ASRNIL--QTHGEWELLGLSKATAKLSRGGNLYDQIVFYVAIRRRPSLYVINLLVPSGFL 246
Query: 367 VVLSWVSFWIHREVGS 382
V + +SF++ + G+
Sbjct: 247 VAIDALSFYLPVKSGN 262
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 41.9 bits (94), Expect = 0.005
Identities = 27/136 (19%), Positives = 61/136 (44%), Gaps = 8/136 (5%)
Query: 253 ISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQ-----WQ-NS 306
+S G I Y + + + C +++ FP D+Q+C L S+ Y+ ++ W+
Sbjct: 159 VSNEGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITD 218
Query: 307 QSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILI 366
S N + T +++L+ +R + + ++R ++I + VP +
Sbjct: 219 ASRNIL--QTHGEWELLGLSKATAKLSRGGNLYDQIVFYVAIRRRPSLYVINLLVPSGFL 276
Query: 367 VVLSWVSFWIHREVGS 382
V + +SF++ + G+
Sbjct: 277 VAIDALSFYLPVKSGN 292
>AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 precursor variant
protein.
Length = 533
Score = 41.9 bits (94), Expect = 0.005
Identities = 27/127 (21%), Positives = 57/127 (44%), Gaps = 3/127 (2%)
Query: 257 GDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQ--LVYQWQNSQSVNFVPG 314
G + ++ K+ C +++ FP D+Q+C + GS+ Y + LV ++F
Sbjct: 53 GRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWES 112
Query: 315 MTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSF 374
D + Y + + + +F ++R ++ I + +PC+LI L+ + F
Sbjct: 113 GEWVIVDAVG-TYNTRKYECCAEIYPDITYAFVIRRLPLFYTINLIIPCLLISCLTVLVF 171
Query: 375 WIHREVG 381
++ E G
Sbjct: 172 YLPSECG 178
>Y18994-1|CAB60835.1| 99|Homo sapiens GABA-C receptor rho3 subunit
protein.
Length = 99
Score = 41.1 bits (92), Expect = 0.010
Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 7/77 (9%)
Query: 449 LTMERTTQTETRVPRWRQLLYCLAGDDRYRRQRQREAGSRGHINSV----SH-IDRAARV 503
+ M++T+ + R+ C D R +R++ G GH+ + +H ID +R+
Sbjct: 24 IDMDQTSLSLNSEDFMRRKSICSPSTDSSRIKRRKSLG--GHVGRIILENNHVIDTYSRI 81
Query: 504 LFPASFALLNLFYWMIY 520
LFP + L NLFYW +Y
Sbjct: 82 LFPIVYILFNLFYWGVY 98
>AK127001-1|BAC86784.1| 133|Homo sapiens protein ( Homo sapiens
cDNA FLJ45056 fis, clone BRAWH3023156, highly similar
to Gamma-aminobutyric-acid receptor beta-1 subunit
precursor. ).
Length = 133
Score = 36.3 bits (80), Expect = 0.27
Identities = 15/45 (33%), Positives = 26/45 (57%)
Query: 476 RYRRQRQREAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIY 520
R RR+ + + V+ ID+ +R+ FP +F+L N+ YW+ Y
Sbjct: 87 RIRRRASQLKVKIPDLTDVNSIDKWSRMFFPITFSLFNVVYWLYY 131
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 35.1 bits (77), Expect = 0.63
Identities = 13/43 (30%), Positives = 24/43 (55%)
Query: 253 ISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYS 295
+S G I Y + + + C +++ FP D+Q+C L S+ Y+
Sbjct: 73 VSNEGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYT 115
>BC050330-1|AAH50330.1| 1459|Homo sapiens ALMS1 protein protein.
Length = 1459
Score = 31.5 bits (68), Expect = 7.7
Identities = 13/30 (43%), Positives = 20/30 (66%)
Query: 475 DRYRRQRQREAGSRGHINSVSHIDRAARVL 504
+R R+QRQ E G R ++ V +DR A++L
Sbjct: 1207 ERQRQQRQPELGDRKELSLVDRLDRLAKIL 1236
>BC035025-1|AAH35025.1| 1459|Homo sapiens ALMS1 protein protein.
Length = 1459
Score = 31.5 bits (68), Expect = 7.7
Identities = 13/30 (43%), Positives = 20/30 (66%)
Query: 475 DRYRRQRQREAGSRGHINSVSHIDRAARVL 504
+R R+QRQ E G R ++ V +DR A++L
Sbjct: 1207 ERQRQQRQPELGDRKELSLVDRLDRLAKIL 1236
>AJ417593-1|CAD10391.2| 4169|Homo sapiens ALMS1 protein protein.
Length = 4169
Score = 31.5 bits (68), Expect = 7.7
Identities = 13/30 (43%), Positives = 20/30 (66%)
Query: 475 DRYRRQRQREAGSRGHINSVSHIDRAARVL 504
+R R+QRQ E G R ++ V +DR A++L
Sbjct: 3608 ERQRQQRQPELGDRKELSLVDRLDRLAKIL 3637
>AC096546-1|AAX82023.1| 1291|Homo sapiens unknown protein.
Length = 1291
Score = 31.5 bits (68), Expect = 7.7
Identities = 13/30 (43%), Positives = 20/30 (66%)
Query: 475 DRYRRQRQREAGSRGHINSVSHIDRAARVL 504
+R R+QRQ E G R ++ V +DR A++L
Sbjct: 1049 ERQRQQRQPELGDRKELSLVDRLDRLAKIL 1078
>AB002326-1|BAA20786.3| 2055|Homo sapiens KIAA0328 protein protein.
Length = 2055
Score = 31.5 bits (68), Expect = 7.7
Identities = 13/30 (43%), Positives = 20/30 (66%)
Query: 475 DRYRRQRQREAGSRGHINSVSHIDRAARVL 504
+R R+QRQ E G R ++ V +DR A++L
Sbjct: 1541 ERQRQQRQPELGDRKELSLVDRLDRLAKIL 1570
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.319 0.133 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 76,564,656
Number of Sequences: 224733
Number of extensions: 3130797
Number of successful extensions: 6251
Number of sequences better than 10.0: 222
Number of HSP's better than 10.0 without gapping: 208
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 5668
Number of HSP's gapped (non-prelim): 328
length of query: 539
length of database: 73,234,838
effective HSP length: 94
effective length of query: 445
effective length of database: 52,109,936
effective search space: 23188921520
effective search space used: 23188921520
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 68 (31.5 bits)
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