BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000888-TA|BGIBMGA000888-PA|IPR003599|Immunoglobulin subtype, IPR003598|Immunoglobulin subtype 2, IPR003961|Fibronectin, type III, IPR013098|Immunoglobulin I-set, IPR013151|Immunoglobulin, IPR007110|Immunoglobulin-like, IPR008957|Fibronectin, type III-like fold (1207 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q174G3 Cluster: Roundabout; n=5; Aedes aegypti|Rep: Rou... 932 0.0 UniRef50_UPI0000D56E5C Cluster: PREDICTED: similar to CG5423-PA;... 925 0.0 UniRef50_Q9GPP6 Cluster: Roundabout 3; n=4; Diptera|Rep: Roundab... 880 0.0 UniRef50_Q9VQ08 Cluster: CG5481-PA; n=6; Diptera|Rep: CG5481-PA ... 722 0.0 UniRef50_UPI0000D55AA5 Cluster: PREDICTED: similar to CG13521-PA... 675 0.0 UniRef50_Q9W213 Cluster: CG13521-PB, isoform B; n=5; Sophophora|... 634 e-180 UniRef50_Q17BD3 Cluster: Roundabout 1; n=3; Culicidae|Rep: Round... 617 e-175 UniRef50_Q17BD5 Cluster: Roundabout; n=1; Aedes aegypti|Rep: Rou... 598 e-169 UniRef50_UPI0000DB7FD0 Cluster: PREDICTED: similar to roundabout... 580 e-163 UniRef50_Q98SW3 Cluster: Transmembrane receptor Roundabout3; n=2... 528 e-148 UniRef50_Q9HCK4 Cluster: Roundabout homolog 2 precursor; n=45; E... 508 e-142 UniRef50_O44928 Cluster: SAX-3; n=3; Caenorhabditis|Rep: SAX-3 -... 506 e-141 UniRef50_Q9Y6N7 Cluster: Roundabout homolog 1 precursor; n=74; C... 500 e-139 UniRef50_Q4RRT1 Cluster: Chromosome 16 SCAF15002, whole genome s... 444 e-123 UniRef50_Q96MS0 Cluster: Roundabout homolog 3 precursor; n=23; E... 436 e-120 UniRef50_UPI0000E4900E Cluster: PREDICTED: similar to transmembr... 429 e-118 UniRef50_UPI0000E46659 Cluster: PREDICTED: similar to roundabout... 412 e-113 UniRef50_UPI0000ECA411 Cluster: UPI0000ECA411 related cluster; n... 341 7e-92 UniRef50_A1XCJ3 Cluster: RoboA; n=1; Schmidtea mediterranea|Rep:... 281 8e-74 UniRef50_UPI0000EBE6C5 Cluster: PREDICTED: hypothetical protein;... 280 1e-73 UniRef50_Q172F7 Cluster: Roundabout, putative; n=2; Culicidae|Re... 268 6e-70 UniRef50_UPI00006A0174 Cluster: Roundabout homolog 4 precursor (... 237 1e-60 UniRef50_Q71B05 Cluster: Roundabout-like protein 4; n=5; Danio r... 227 2e-57 UniRef50_Q4SCT9 Cluster: Chromosome 7 SCAF14650, whole genome sh... 219 3e-55 UniRef50_UPI000065EA6D Cluster: Homolog of Brachydanio rerio "Ro... 219 5e-55 UniRef50_Q96RW7 Cluster: Hemicentin-1 precursor; n=40; Eumetazoa... 206 4e-51 UniRef50_Q4RJ20 Cluster: Chromosome 1 SCAF15039, whole genome sh... 204 9e-51 UniRef50_Q4SL83 Cluster: Chromosome 7 SCAF14557, whole genome sh... 203 2e-50 UniRef50_Q92626 Cluster: Peroxidasin homolog; n=49; Eumetazoa|Re... 201 8e-50 UniRef50_Q4SR23 Cluster: Chromosome 11 SCAF14528, whole genome s... 187 1e-45 UniRef50_Q4S2G3 Cluster: Chromosome undetermined SCAF14761, whol... 186 2e-45 UniRef50_UPI0000E460A7 Cluster: PREDICTED: similar to OTTHUMP000... 182 7e-44 UniRef50_P97798 Cluster: Neogenin precursor; n=37; Euteleostomi|... 177 1e-42 UniRef50_UPI0000D9D2C3 Cluster: PREDICTED: similar to peroxidasi... 177 2e-42 UniRef50_A7S5L2 Cluster: Predicted protein; n=1; Nematostella ve... 175 5e-42 UniRef50_UPI0000F2BDAE Cluster: PREDICTED: similar to hCG1996527... 174 1e-41 UniRef50_UPI0000DA21B5 Cluster: PREDICTED: similar to hemicentin... 170 2e-40 UniRef50_Q4S8U5 Cluster: Chromosome 7 SCAF14703, whole genome sh... 170 2e-40 UniRef50_UPI00004DA303 Cluster: UPI00004DA303 related cluster; n... 170 2e-40 UniRef50_Q02246 Cluster: Contactin-2 precursor; n=38; Euteleosto... 169 3e-40 UniRef50_UPI0000F34A69 Cluster: UPI0000F34A69 related cluster; n... 168 7e-40 UniRef50_Q92859 Cluster: Neogenin precursor; n=34; Euteleostomi|... 168 7e-40 UniRef50_O94779 Cluster: Contactin-5 precursor; n=52; Euteleosto... 167 2e-39 UniRef50_UPI0000F2B6E2 Cluster: PREDICTED: hypothetical protein;... 166 3e-39 UniRef50_UPI00004D4C52 Cluster: Roundabout homolog 4 precursor (... 166 3e-39 UniRef50_Q7Z5N4 Cluster: Protein sidekick-1 precursor; n=62; Eut... 165 6e-39 UniRef50_Q8TD84 Cluster: Down syndrome cell adhesion molecule-li... 164 1e-38 UniRef50_UPI0000DB7011 Cluster: PREDICTED: similar to CG33519-PB... 164 1e-38 UniRef50_A2CEC7 Cluster: Novel protein similar to Down syndrome ... 163 2e-38 UniRef50_Q8NDA2 Cluster: Hemicentin-2; n=28; Euteleostomi|Rep: H... 163 3e-38 UniRef50_Q5XNV8 Cluster: Neogenin/DCC long isoform; n=5; Vertebr... 162 5e-38 UniRef50_Q4RYE5 Cluster: Chromosome 2 SCAF14976, whole genome sh... 162 5e-38 UniRef50_Q8IVU1 Cluster: Putative neuronal cell adhesion molecul... 162 5e-38 UniRef50_Q9UQ52 Cluster: Contactin-6 precursor; n=78; Euteleosto... 162 5e-38 UniRef50_O76518 Cluster: Hemicentin precursor; n=4; Eukaryota|Re... 161 1e-37 UniRef50_UPI00005BDC8C Cluster: PREDICTED: similar to hemicentin... 161 1e-37 UniRef50_UPI0000F1ECB4 Cluster: PREDICTED: similar to hemicentin... 160 2e-37 UniRef50_Q9VS29 Cluster: CG32387-PA, isoform A; n=15; Endopteryg... 160 2e-37 UniRef50_UPI000065D4F5 Cluster: Homolog of Danio rerio "Novel he... 159 4e-37 UniRef50_UPI0000E48C89 Cluster: PREDICTED: similar to Nr-CAM pro... 159 6e-37 UniRef50_Q12860 Cluster: Contactin-1 precursor; n=31; Euteleosto... 159 6e-37 UniRef50_UPI0000D57997 Cluster: PREDICTED: similar to CG33519-PB... 157 2e-36 UniRef50_Q2VWP7 Cluster: Protogenin homolog; n=32; Euteleostomi|... 157 2e-36 UniRef50_Q6WRI0 Cluster: Immunoglobulin superfamily member 10 pr... 156 4e-36 UniRef50_Q49AK4 Cluster: DCC protein; n=9; Euteleostomi|Rep: DCC... 155 7e-36 UniRef50_UPI0000E47894 Cluster: PREDICTED: similar to scavenger ... 155 9e-36 UniRef50_UPI0000D8E943 Cluster: Down syndrome cell adhesion mole... 155 9e-36 UniRef50_A6BM71 Cluster: Connectin; n=8; Gallus gallus|Rep: Conn... 155 9e-36 UniRef50_P20241 Cluster: Neuroglian precursor; n=17; Endopterygo... 154 1e-35 UniRef50_Q0E9K8 Cluster: CG17800-PAN; n=84; Endopterygota|Rep: C... 153 3e-35 UniRef50_A5X6X5 Cluster: Titin a; n=10; Euteleostomi|Rep: Titin ... 152 5e-35 UniRef50_UPI0000D576E1 Cluster: PREDICTED: similar to CG12002-PA... 151 9e-35 UniRef50_Q4RJ21 Cluster: Chromosome 1 SCAF15039, whole genome sh... 151 1e-34 UniRef50_A7SM31 Cluster: Predicted protein; n=1; Nematostella ve... 151 1e-34 UniRef50_UPI000155CDCD Cluster: PREDICTED: similar to adlican; n... 151 1e-34 UniRef50_Q0E8G9 Cluster: CG33274-PB; n=9; Endopterygota|Rep: CG3... 149 3e-34 UniRef50_Q58EX2 Cluster: Protein sidekick-2 precursor; n=19; Eut... 148 8e-34 UniRef50_UPI0000E80BF7 Cluster: PREDICTED: similar to bone speci... 148 1e-33 UniRef50_UPI0000D56997 Cluster: PREDICTED: similar to CG8581-PA,... 147 1e-33 UniRef50_Q59E65 Cluster: CG33519-PB; n=5; Sophophora|Rep: CG3351... 147 1e-33 UniRef50_Q8WZ75 Cluster: Roundabout homolog 4 precursor; n=22; T... 146 2e-33 UniRef50_Q9NR99 Cluster: Matrix-remodeling-associated protein 5 ... 146 2e-33 UniRef50_Q4S6A5 Cluster: Chromosome 9 SCAF14729, whole genome sh... 146 3e-33 UniRef50_O18465 Cluster: Tractin; n=7; Coelomata|Rep: Tractin - ... 146 3e-33 UniRef50_O01761 Cluster: Muscle M-line assembly protein unc-89; ... 146 3e-33 UniRef50_Q13308 Cluster: Tyrosine-protein kinase-like 7 precurso... 146 3e-33 UniRef50_O00533 Cluster: Neural cell adhesion molecule L1-like p... 146 3e-33 UniRef50_Q4SR20 Cluster: Chromosome 11 SCAF14528, whole genome s... 145 6e-33 UniRef50_Q98902 Cluster: Neural cell adhesion molecule L1 precur... 145 6e-33 UniRef50_UPI0000E4A6A5 Cluster: PREDICTED: similar to heparan su... 145 7e-33 UniRef50_Q4T8B2 Cluster: Chromosome undetermined SCAF7849, whole... 145 7e-33 UniRef50_UPI0000F2E6F1 Cluster: PREDICTED: similar to L1 cell ad... 144 1e-32 UniRef50_UPI0000F1EDBC Cluster: PREDICTED: similar to adlican; n... 144 2e-32 UniRef50_Q4RVM2 Cluster: Chromosome 9 SCAF14991, whole genome sh... 144 2e-32 UniRef50_A4JYE0 Cluster: CDNA, clone cssl:d0205; n=2; Danio reri... 144 2e-32 UniRef50_P32004 Cluster: Neural cell adhesion molecule L1 precur... 143 2e-32 UniRef50_UPI0000E815E6 Cluster: PREDICTED: similar to roundabout... 143 3e-32 UniRef50_P98160 Cluster: Basement membrane-specific heparan sulf... 143 3e-32 UniRef50_UPI0000E46295 Cluster: PREDICTED: similar to Down syndr... 142 4e-32 UniRef50_Q4RE92 Cluster: Chromosome undetermined SCAF15134, whol... 142 5e-32 UniRef50_Q8WZ42 Cluster: Titin; n=65; Eukaryota|Rep: Titin - Hom... 141 9e-32 UniRef50_Q4SHH6 Cluster: Chromosome 5 SCAF14581, whole genome sh... 141 1e-31 UniRef50_UPI00004D93F2 Cluster: immunoglobulin superfamily, memb... 140 2e-31 UniRef50_UPI0000DB6D93 Cluster: PREDICTED: similar to CG32387-PB... 138 6e-31 UniRef50_O97394 Cluster: Protein sidekick precursor; n=9; Endopt... 138 9e-31 UniRef50_UPI0000E47478 Cluster: PREDICTED: similar to hemicentin... 138 1e-30 UniRef50_Q8C310-3 Cluster: Isoform 3 of Q8C310 ; n=2; Murinae|Re... 138 1e-30 UniRef50_UPI0000F33D9D Cluster: Perlecan; n=1; Bos taurus|Rep: P... 137 2e-30 UniRef50_Q4RVM0 Cluster: Chromosome 9 SCAF14991, whole genome sh... 136 3e-30 UniRef50_A2AT18 Cluster: Titin; n=11; Eukaryota|Rep: Titin - Mus... 136 3e-30 UniRef50_Q4RY92 Cluster: Chromosome 3 SCAF14978, whole genome sh... 136 5e-30 UniRef50_UPI0000DB6C79 Cluster: PREDICTED: similar to PTK7 prote... 134 2e-29 UniRef50_Q4S2G4 Cluster: Chromosome undetermined SCAF14761, whol... 134 2e-29 UniRef50_O94856 Cluster: Neurofascin precursor; n=64; Euteleosto... 133 2e-29 UniRef50_Q4SR22 Cluster: Chromosome 11 SCAF14528, whole genome s... 133 3e-29 UniRef50_UPI0000DB7802 Cluster: PREDICTED: similar to Neogenin p... 132 4e-29 UniRef50_Q4TAD5 Cluster: Chromosome undetermined SCAF7373, whole... 132 4e-29 UniRef50_Q7QEI6 Cluster: ENSANGP00000020451; n=1; Anopheles gamb... 132 6e-29 UniRef50_Q810U4 Cluster: Neuronal cell adhesion molecule precurs... 132 6e-29 UniRef50_UPI00006607E8 Cluster: Homolog of Homo sapiens "OTTHUMP... 132 7e-29 UniRef50_UPI000065FAD3 Cluster: Homolog of Brachydanio rerio "Ne... 131 1e-28 UniRef50_Q92823 Cluster: Neuronal cell adhesion molecule precurs... 131 1e-28 UniRef50_Q08CM9 Cluster: Zgc:152904; n=12; Euteleostomi|Rep: Zgc... 130 2e-28 UniRef50_Q03696 Cluster: Neuronal-glial cell adhesion molecule p... 130 2e-28 UniRef50_Q1JUB3 Cluster: L1-like cell adhesion molecule; n=1; Du... 130 2e-28 UniRef50_UPI0000E4747A Cluster: PREDICTED: similar to neuroglian... 129 4e-28 UniRef50_Q4RZE9 Cluster: Chromosome undetermined SCAF14935, whol... 129 4e-28 UniRef50_UPI000065D5B9 Cluster: Contactin-4 precursor (Brain-der... 128 7e-28 UniRef50_UPI0000E4A418 Cluster: PREDICTED: similar to axonin-1; ... 128 1e-27 UniRef50_UPI0000D5796D Cluster: PREDICTED: similar to CG31190-PA... 127 2e-27 UniRef50_Q4SIF9 Cluster: Chromosome 5 SCAF14581, whole genome sh... 126 4e-27 UniRef50_Q8TDY8 Cluster: Neighbor of punc e11 precursor; n=23; T... 126 4e-27 UniRef50_UPI00015B613E Cluster: PREDICTED: similar to frazzled p... 125 6e-27 UniRef50_Q9VN14 Cluster: Contactin precursor; n=4; Endopterygota... 125 6e-27 UniRef50_UPI0000519A30 Cluster: PREDICTED: similar to Peroxidasi... 124 1e-26 UniRef50_UPI0000D560FB Cluster: PREDICTED: similar to CG1084-PA;... 124 2e-26 UniRef50_UPI0000D55944 Cluster: PREDICTED: similar to CG8967-PA;... 123 3e-26 UniRef50_A7RGL7 Cluster: Predicted protein; n=1; Nematostella ve... 123 3e-26 UniRef50_UPI00006A0696 Cluster: DDM36; n=4; Tetrapoda|Rep: DDM36... 123 3e-26 UniRef50_Q4SI43 Cluster: Chromosome 5 SCAF14581, whole genome sh... 123 3e-26 UniRef50_UPI0000ECA0F8 Cluster: Neurofascin precursor.; n=3; Gal... 122 5e-26 UniRef50_Q59FX6 Cluster: Protein tyrosine phosphatase, receptor ... 122 6e-26 UniRef50_Q4RVZ3 Cluster: Chromosome 9 SCAF14991, whole genome sh... 122 8e-26 UniRef50_P13591 Cluster: Neural cell adhesion molecule 1, 140 kD... 122 8e-26 UniRef50_UPI0000DB6DF8 Cluster: PREDICTED: similar to leucine-ri... 121 1e-25 UniRef50_UPI00015B6341 Cluster: PREDICTED: similar to KLG; n=1; ... 120 2e-25 UniRef50_Q23991 Cluster: Peroxidasin precursor; n=7; Coelomata|R... 120 2e-25 UniRef50_A7RGM2 Cluster: Predicted protein; n=1; Nematostella ve... 120 2e-25 UniRef50_O15394 Cluster: Neural cell adhesion molecule 2 precurs... 120 2e-25 UniRef50_Q90478 Cluster: Neural cell adhesion molecule L1.1; n=9... 120 2e-25 UniRef50_UPI0000ECD748 Cluster: UPI0000ECD748 related cluster; n... 120 3e-25 UniRef50_A7S4D5 Cluster: Predicted protein; n=1; Nematostella ve... 118 7e-25 UniRef50_UPI00015B5045 Cluster: PREDICTED: similar to receptor t... 118 1e-24 UniRef50_Q4SPP8 Cluster: Chromosome 16 SCAF14537, whole genome s... 118 1e-24 UniRef50_Q94155 Cluster: Unc-40 protein; n=2; Caenorhabditis|Rep... 118 1e-24 UniRef50_A7RNP0 Cluster: Predicted protein; n=2; Nematostella ve... 117 2e-24 UniRef50_UPI00015A4156 Cluster: Neogenin precursor.; n=1; Danio ... 117 2e-24 UniRef50_Q4RRR9 Cluster: Chromosome 16 SCAF15002, whole genome s... 117 2e-24 UniRef50_Q8NFA8 Cluster: Transmembrane receptor PTK7-2; n=18; Eu... 117 2e-24 UniRef50_Q4KMQ7 Cluster: NRCAM protein; n=10; Euteleostomi|Rep: ... 117 2e-24 UniRef50_Q4S5S6 Cluster: Chromosome 9 SCAF14729, whole genome sh... 116 4e-24 UniRef50_A7SVH4 Cluster: Predicted protein; n=2; Nematostella ve... 116 4e-24 UniRef50_UPI0000D57760 Cluster: PREDICTED: similar to leucine-ri... 116 5e-24 UniRef50_O44329 Cluster: Receptor tyrosine phosphatase; n=1; Hir... 116 5e-24 UniRef50_P16621 Cluster: Tyrosine-protein phosphatase Lar precur... 116 5e-24 UniRef50_UPI00015A60B9 Cluster: UPI00015A60B9 related cluster; n... 115 7e-24 UniRef50_Q4RHM3 Cluster: Chromosome 19 SCAF15045, whole genome s... 115 7e-24 UniRef50_UPI00015B5487 Cluster: PREDICTED: similar to leucine-ri... 115 9e-24 UniRef50_UPI00015A3FB5 Cluster: hypothetical protein LOC553690; ... 115 9e-24 UniRef50_Q7KSE9 Cluster: CG31190-PB, isoform B; n=4; Diptera|Rep... 115 9e-24 UniRef50_Q6IDE9 Cluster: LP21844p; n=2; Sophophora|Rep: LP21844p... 115 9e-24 UniRef50_UPI0000E468FC Cluster: PREDICTED: similar to KLG; n=3; ... 114 1e-23 UniRef50_A0S6W8 Cluster: Hemicentin-like protein 2; n=2; Spodopt... 114 1e-23 UniRef50_UPI0000F1ECB5 Cluster: PREDICTED: similar to novel hemi... 114 2e-23 UniRef50_A7RGL8 Cluster: Predicted protein; n=1; Nematostella ve... 113 2e-23 UniRef50_A7RGM0 Cluster: Predicted protein; n=1; Nematostella ve... 113 4e-23 UniRef50_UPI0000E46E64 Cluster: PREDICTED: similar to SAPS287; n... 112 6e-23 UniRef50_UPI0000DB72ED Cluster: PREDICTED: similar to CG33950-PD... 112 6e-23 UniRef50_Q4SPP9 Cluster: Chromosome 16 SCAF14537, whole genome s... 112 6e-23 UniRef50_A7RQE6 Cluster: Predicted protein; n=3; Nematostella ve... 112 6e-23 UniRef50_O15146 Cluster: Muscle, skeletal receptor tyrosine prot... 112 6e-23 UniRef50_Q13332 Cluster: Receptor-type tyrosine-protein phosphat... 111 8e-23 UniRef50_Q15746 Cluster: Myosin light chain kinase, smooth muscl... 111 8e-23 UniRef50_Q96JA1 Cluster: Leucine-rich repeats and immunoglobulin... 111 8e-23 UniRef50_Q4KMG0 Cluster: Cell adhesion molecule-related/down-reg... 111 8e-23 UniRef50_UPI0000546958 Cluster: PREDICTED: hypothetical protein;... 111 1e-22 UniRef50_UPI0000DB7443 Cluster: PREDICTED: similar to Fasciclin ... 111 1e-22 UniRef50_Q8WR45 Cluster: Immunoglobulin domain-containing protei... 111 1e-22 UniRef50_A7SC07 Cluster: Predicted protein; n=1; Nematostella ve... 111 1e-22 UniRef50_Q8AXY6 Cluster: Muscle, skeletal receptor tyrosine prot... 110 2e-22 UniRef50_Q9I7U4-3 Cluster: Isoform B of Q9I7U4 ; n=6; Sophophora... 110 3e-22 UniRef50_Q4TBR4 Cluster: Chromosome undetermined SCAF7099, whole... 110 3e-22 UniRef50_Q0E8J3 Cluster: CG33484-PD, isoform D; n=9; Sophophora|... 110 3e-22 UniRef50_UPI00015B41E3 Cluster: PREDICTED: similar to fasciclin ... 109 3e-22 UniRef50_UPI00015B50B3 Cluster: PREDICTED: similar to cell adhes... 109 5e-22 UniRef50_A7SVH6 Cluster: Predicted protein; n=1; Nematostella ve... 109 5e-22 UniRef50_A7SSL0 Cluster: Predicted protein; n=1; Nematostella ve... 109 5e-22 UniRef50_UPI0000E4617C Cluster: PREDICTED: similar to novel immu... 109 6e-22 UniRef50_UPI0000DB6E73 Cluster: PREDICTED: similar to CG31190-PB... 109 6e-22 UniRef50_Q4SW90 Cluster: Chromosome undetermined SCAF13667, whol... 109 6e-22 UniRef50_A1Z920 Cluster: CG8581-PA, isoform A; n=8; Diptera|Rep:... 109 6e-22 UniRef50_O94898 Cluster: Leucine-rich repeats and immunoglobulin... 109 6e-22 UniRef50_Q61YY0 Cluster: Putative uncharacterized protein CBG033... 108 8e-22 UniRef50_UPI0000D55E60 Cluster: PREDICTED: similar to CG32796-PB... 108 1e-21 UniRef50_Q17AC3 Cluster: Leucine-rich transmembrane protein; n=2... 108 1e-21 UniRef50_UPI0000DB720E Cluster: PREDICTED: similar to zormin CG3... 107 1e-21 UniRef50_Q4S1C0 Cluster: Chromosome 13 SCAF14769, whole genome s... 107 1e-21 UniRef50_A4JYL6 Cluster: Sid4; n=4; Clupeocephala|Rep: Sid4 - Da... 107 1e-21 UniRef50_UPI0000E472F4 Cluster: PREDICTED: similar to SEC14 and ... 107 2e-21 UniRef50_UPI00004D1686 Cluster: Neogenin precursor.; n=1; Xenopu... 107 2e-21 UniRef50_Q4RKK6 Cluster: Chromosome 5 SCAF15028, whole genome sh... 107 2e-21 UniRef50_Q7Q0S6 Cluster: ENSANGP00000006166; n=5; cellular organ... 107 2e-21 UniRef50_P23468 Cluster: Receptor-type tyrosine-protein phosphat... 107 2e-21 UniRef50_UPI0000F2186B Cluster: PREDICTED: hypothetical protein;... 106 3e-21 UniRef50_Q6UXM1 Cluster: Leucine-rich repeats and immunoglobulin... 106 3e-21 UniRef50_Q8UVD6 Cluster: Brother of CDO; n=2; Danio rerio|Rep: B... 106 4e-21 UniRef50_Q4RRS5 Cluster: Chromosome 16 SCAF15002, whole genome s... 106 4e-21 UniRef50_Q1ENI8 Cluster: Peroxidasin (Drosophila peroxidase) hom... 106 4e-21 UniRef50_UPI0000DB6DA9 Cluster: PREDICTED: similar to CG32387-PB... 105 6e-21 UniRef50_Q7Q3K8 Cluster: ENSANGP00000009916; n=4; Endopterygota|... 104 1e-20 UniRef50_A7TCD9 Cluster: Predicted protein; n=1; Nematostella ve... 104 1e-20 UniRef50_UPI00015B5ECA Cluster: PREDICTED: similar to rCG56583; ... 103 2e-20 UniRef50_Q7SY58 Cluster: Muscle, skeletal, receptor tyrosine kin... 103 3e-20 UniRef50_A0JM54 Cluster: LOC100036605 protein; n=1; Xenopus trop... 103 4e-20 UniRef50_Q6UXZ4 Cluster: Netrin receptor UNC5D precursor; n=44; ... 103 4e-20 UniRef50_Q6PDN3 Cluster: Myosin light chain kinase, smooth muscl... 103 4e-20 UniRef50_Q9UPX0 Cluster: Protein turtle homolog B precursor; n=2... 102 5e-20 UniRef50_UPI0000E48847 Cluster: PREDICTED: similar to titin isof... 102 7e-20 UniRef50_Q9BMN8 Cluster: Tyrosine-protein phosphatase Lar-like p... 102 7e-20 UniRef50_A7RK32 Cluster: Predicted protein; n=2; Nematostella ve... 100 2e-19 UniRef50_Q8IZJ1 Cluster: Netrin receptor UNC5B precursor; n=38; ... 100 2e-19 UniRef50_Q6UWL6 Cluster: Kin of IRRE-like protein 2 precursor; n... 100 2e-19 UniRef50_UPI0000F20186 Cluster: PREDICTED: similar to cell adhes... 100 3e-19 UniRef50_Q4S556 Cluster: Chromosome 6 SCAF14737, whole genome sh... 100 3e-19 UniRef50_UPI0000E4A8AD Cluster: PREDICTED: similar to Ptprd prot... 99 4e-19 UniRef50_UPI000065CE26 Cluster: Homolog of Homo sapiens "Hemicen... 99 4e-19 UniRef50_P34082 Cluster: Fasciclin-2 precursor; n=7; Diptera|Rep... 99 4e-19 UniRef50_Q9W4Y3 Cluster: CG33950-PF, isoform F; n=13; Coelomata|... 100 5e-19 UniRef50_UPI0000D55C03 Cluster: PREDICTED: similar to CG33484-PA... 99 6e-19 UniRef50_A7SQE0 Cluster: Predicted protein; n=1; Nematostella ve... 99 6e-19 UniRef50_Q9P2J2 Cluster: Protein turtle homolog A precursor; n=2... 99 6e-19 UniRef50_UPI00015B59DF Cluster: PREDICTED: similar to turtle pro... 99 8e-19 UniRef50_Q4T1M4 Cluster: Chromosome undetermined SCAF10538, whol... 99 8e-19 UniRef50_Q4RHM4 Cluster: Chromosome 19 SCAF15045, whole genome s... 99 8e-19 UniRef50_A7RGM1 Cluster: Predicted protein; n=1; Nematostella ve... 99 8e-19 UniRef50_Q4RVM1 Cluster: Chromosome 9 SCAF14991, whole genome sh... 98 1e-18 UniRef50_Q9BWV1 Cluster: Brother of CDO precursor; n=27; Euteleo... 98 1e-18 UniRef50_Q4SCU0 Cluster: Chromosome 7 SCAF14650, whole genome sh... 97 2e-18 UniRef50_Q967D7 Cluster: Protein turtle; n=5; Drosophila melanog... 97 2e-18 UniRef50_A7RNL2 Cluster: Predicted protein; n=1; Nematostella ve... 97 3e-18 UniRef50_Q4RQ36 Cluster: Chromosome 17 SCAF15006, whole genome s... 97 3e-18 UniRef50_Q9I7U4 Cluster: Titin; n=7; Endopterygota|Rep: Titin - ... 97 3e-18 UniRef50_Q4RRD1 Cluster: Chromosome 16 SCAF15002, whole genome s... 96 6e-18 UniRef50_P11799 Cluster: Myosin light chain kinase, smooth muscl... 96 6e-18 UniRef50_Q8NFP4 Cluster: MAM domain-containing glycosylphosphati... 96 6e-18 UniRef50_P22648 Cluster: Fasciclin-2 precursor; n=1; Schistocerc... 96 6e-18 UniRef50_UPI0000E46FA4 Cluster: PREDICTED: similar to protein ty... 95 8e-18 UniRef50_Q1L8D0 Cluster: Cell adhesion molecule-related/down-reg... 95 8e-18 UniRef50_UPI0000E4A429 Cluster: PREDICTED: similar to guanine de... 95 1e-17 UniRef50_UPI0000D56C0A Cluster: PREDICTED: similar to CG6669-PA;... 95 1e-17 UniRef50_A7S831 Cluster: Predicted protein; n=1; Nematostella ve... 95 1e-17 UniRef50_O18466 Cluster: LeechCAM; n=1; Hirudo medicinalis|Rep: ... 94 2e-17 UniRef50_A7SVH5 Cluster: Predicted protein; n=1; Nematostella ve... 94 2e-17 UniRef50_A4JYK0 Cluster: Si:dkey-24p1.1; n=3; Danio rerio|Rep: S... 94 2e-17 UniRef50_A7T084 Cluster: Predicted protein; n=1; Nematostella ve... 94 2e-17 UniRef50_A7T3W0 Cluster: Predicted protein; n=1; Nematostella ve... 93 3e-17 UniRef50_A7RT26 Cluster: Predicted protein; n=1; Nematostella ve... 93 3e-17 UniRef50_UPI0000D56EF9 Cluster: PREDICTED: similar to CG12676-PA... 93 6e-17 UniRef50_Q6R3L9 Cluster: Hemolin; n=5; Bombyx|Rep: Hemolin - Bom... 93 6e-17 UniRef50_Q6UWL6-4 Cluster: Isoform 4 of Q6UWL6 ; n=6; Catarrhini... 92 1e-16 UniRef50_A7RTW2 Cluster: Predicted protein; n=1; Nematostella ve... 91 1e-16 UniRef50_O95185 Cluster: Netrin receptor UNC5C precursor; n=54; ... 91 1e-16 UniRef50_O75147 Cluster: Obscurin-like protein 1 precursor; n=35... 91 1e-16 UniRef50_UPI0000F1EF3F Cluster: PREDICTED: hypothetical protein;... 91 2e-16 UniRef50_UPI0000E46F13 Cluster: PREDICTED: similar to CG33141-PB... 91 2e-16 UniRef50_UPI0000D9DD6E Cluster: PREDICTED: similar to hemicentin... 91 2e-16 UniRef50_Q06561 Cluster: Basement membrane proteoglycan precurso... 91 2e-16 UniRef50_Q7YT99 Cluster: Twitchin; n=4; Mollusca|Rep: Twitchin -... 91 2e-16 UniRef50_UPI000051A210 Cluster: PREDICTED: similar to CG32796-PB... 90 3e-16 UniRef50_UPI00006602C0 Cluster: Netrin receptor UNC5D precursor ... 90 3e-16 UniRef50_UPI0000ECAAF1 Cluster: Netrin receptor UNC5A precursor ... 90 3e-16 UniRef50_UPI000065E234 Cluster: Homolog of Homo sapiens "OTTHUMP... 90 4e-16 UniRef50_Q9TWA6 Cluster: APCAM=CELL adhesion molecule from CDNA ... 90 4e-16 UniRef50_Q9BIA2 Cluster: Neuronal igcam protein 6, isoform b; n=... 90 4e-16 UniRef50_A7SWF5 Cluster: Predicted protein; n=3; Nematostella ve... 90 4e-16 UniRef50_UPI0000EB292A Cluster: Leucine-rich repeats and immunog... 89 7e-16 UniRef50_Q4SJF7 Cluster: Chromosome 4 SCAF14575, whole genome sh... 89 7e-16 UniRef50_O97137 Cluster: Fasciclin II transmembrane isoform; n=3... 89 7e-16 UniRef50_Q6PF50 Cluster: MGC68902 protein; n=2; Xenopus|Rep: MGC... 89 9e-16 UniRef50_Q9VNP2 Cluster: CG8779-PA, isoform A; n=3; Drosophila m... 89 9e-16 UniRef50_Q00872 Cluster: Myosin-binding protein C, slow-type; n=... 89 9e-16 UniRef50_UPI000065D2BB Cluster: Homolog of Homo sapiens "Palladi... 88 2e-15 UniRef50_Q53U87 Cluster: SAX-7 LONGFORM; n=6; Caenorhabditis|Rep... 88 2e-15 UniRef50_Q15772 Cluster: Striated muscle preferentially expresse... 88 2e-15 UniRef50_P31398 Cluster: Hemolin precursor; n=12; Obtectomera|Re... 88 2e-15 UniRef50_UPI0000E49A7A Cluster: PREDICTED: hypothetical protein,... 87 2e-15 UniRef50_UPI0000E46930 Cluster: PREDICTED: similar to sidekick-2... 87 2e-15 UniRef50_UPI0000DB7010 Cluster: PREDICTED: similar to CG33519-PB... 87 2e-15 UniRef50_Q5W9G3 Cluster: LAR splice variant 1; n=24; Eutheria|Re... 87 2e-15 UniRef50_Q95TU8 Cluster: Netrin receptor unc-5 precursor; n=3; D... 87 2e-15 UniRef50_UPI0000519C8D Cluster: PREDICTED: similar to echinoid C... 87 3e-15 UniRef50_Q4TAJ7 Cluster: Chromosome undetermined SCAF7304, whole... 87 3e-15 UniRef50_Q11WJ9 Cluster: CHU large protein; uncharacterized; n=1... 87 3e-15 UniRef50_Q7Z553 Cluster: MAM domain-containing glycosylphosphati... 87 3e-15 UniRef50_UPI0000DB8006 Cluster: PREDICTED: similar to sallimus C... 87 4e-15 UniRef50_UPI0000E815EC Cluster: PREDICTED: hypothetical protein;... 86 5e-15 UniRef50_Q4RFN0 Cluster: Chromosome 16 SCAF15113, whole genome s... 86 5e-15 UniRef50_A7SM30 Cluster: Predicted protein; n=1; Nematostella ve... 86 5e-15 UniRef50_UPI00006A231D Cluster: Brother of CDO precursor (Protei... 86 6e-15 UniRef50_UPI000065EC1F Cluster: Homolog of Homo sapiens "Obscuri... 86 6e-15 UniRef50_Q0E9F2 Cluster: CG33141-PB, isoform B; n=9; Diptera|Rep... 86 6e-15 UniRef50_A2AAJ9 Cluster: Obscurin; n=10; Eutheria|Rep: Obscurin ... 86 6e-15 UniRef50_Q9U8G8 Cluster: Lacunin precursor; n=1; Manduca sexta|R... 85 8e-15 UniRef50_P0C5E3 Cluster: Palladin; n=24; Amniota|Rep: Palladin -... 85 8e-15 UniRef50_Q5VST9 Cluster: Obscurin; n=50; Amniota|Rep: Obscurin -... 85 8e-15 UniRef50_Q7PMY4 Cluster: ENSANGP00000014155; n=2; Culicidae|Rep:... 85 1e-14 UniRef50_Q17AF2 Cluster: Myosin light chain kinase; n=1; Aedes a... 85 1e-14 UniRef50_Q308M3 Cluster: Protein tyrosine phosphatase receptor t... 85 1e-14 UniRef50_UPI00015B4DC5 Cluster: PREDICTED: similar to ENSANGP000... 85 1e-14 UniRef50_UPI0000F1F64B Cluster: PREDICTED: hypothetical protein;... 85 1e-14 UniRef50_Q4R5Y9 Cluster: Testis cDNA, clone: QtsA-19723, similar... 85 1e-14 UniRef50_Q9VCT4 Cluster: CG6669-PA; n=8; Diptera|Rep: CG6669-PA ... 85 1e-14 UniRef50_Q9U4G1 Cluster: CG16857-PA; n=8; Endopterygota|Rep: CG1... 85 1e-14 UniRef50_A7TAR2 Cluster: Predicted protein; n=1; Nematostella ve... 85 1e-14 UniRef50_A7T325 Cluster: Predicted protein; n=1; Nematostella ve... 85 1e-14 UniRef50_UPI0000F1FF89 Cluster: PREDICTED: hypothetical protein;... 84 2e-14 UniRef50_Q4S6A6 Cluster: Chromosome 9 SCAF14729, whole genome sh... 84 2e-14 UniRef50_A5PMX0 Cluster: Novel protein; n=4; Danio rerio|Rep: No... 84 2e-14 UniRef50_UPI0000E4A76B Cluster: PREDICTED: similar to NCAM-140; ... 84 3e-14 UniRef50_Q4SF99 Cluster: Chromosome undetermined SCAF14606, whol... 84 3e-14 UniRef50_Q2IPN8 Cluster: Putative vgr-related protein; n=1; Anae... 84 3e-14 UniRef50_Q7QJK9 Cluster: ENSANGP00000010739; n=1; Anopheles gamb... 84 3e-14 UniRef50_Q21043 Cluster: Putative uncharacterized protein pxn-2;... 84 3e-14 UniRef50_A7T5G7 Cluster: Predicted protein; n=1; Nematostella ve... 84 3e-14 UniRef50_Q8WX93 Cluster: Palladin; n=14; Euarchontoglires|Rep: P... 84 3e-14 UniRef50_UPI0000DB6FFA Cluster: PREDICTED: similar to Papilin CG... 83 3e-14 UniRef50_Q4SAP3 Cluster: Chromosome undetermined SCAF14681, whol... 83 3e-14 UniRef50_Q25198 Cluster: Receptor tyrosine kinase 90; n=1; Hydra... 83 3e-14 UniRef50_Q17HV8 Cluster: Myomesin; n=3; Culicidae|Rep: Myomesin ... 83 3e-14 UniRef50_A7S735 Cluster: Predicted protein; n=1; Nematostella ve... 83 3e-14 UniRef50_UPI0000DB7435 Cluster: PREDICTED: similar to unc-5 homo... 83 4e-14 UniRef50_UPI00015A6DFF Cluster: UPI00015A6DFF related cluster; n... 83 4e-14 UniRef50_Q4RQR3 Cluster: Chromosome 2 SCAF15004, whole genome sh... 83 4e-14 UniRef50_A7RYG0 Cluster: Predicted protein; n=1; Nematostella ve... 83 4e-14 UniRef50_Q4TBU1 Cluster: Chromosome undetermined SCAF7089, whole... 83 6e-14 UniRef50_P79757 Cluster: Connectin/titin; n=3; Amniota|Rep: Conn... 83 6e-14 UniRef50_O44328 Cluster: Receptor tyrosine phosphatase; n=6; Eum... 83 6e-14 UniRef50_Q9UBF9 Cluster: Myotilin; n=18; Tetrapoda|Rep: Myotilin... 83 6e-14 UniRef50_UPI00015B6345 Cluster: PREDICTED: similar to CG33141-PB... 82 8e-14 UniRef50_Q9W4Y6 Cluster: CG32796-PB, isoform B; n=4; Drosophila ... 82 8e-14 UniRef50_Q1RKQ9 Cluster: IP03437p; n=12; Diptera|Rep: IP03437p -... 82 8e-14 UniRef50_UPI000069DD8B Cluster: Leucine-rich repeats and immunog... 82 1e-13 UniRef50_UPI0000EB3119 Cluster: UPI0000EB3119 related cluster; n... 82 1e-13 UniRef50_UPI00015B4AAE Cluster: PREDICTED: hypothetical protein;... 81 1e-13 UniRef50_UPI00006A2827 Cluster: UPI00006A2827 related cluster; n... 81 1e-13 UniRef50_Q9BN17 Cluster: Echinoid; n=10; Diptera|Rep: Echinoid -... 81 1e-13 UniRef50_Q290N6 Cluster: GA21440-PA; n=1; Drosophila pseudoobscu... 81 1e-13 UniRef50_A7T115 Cluster: Predicted protein; n=2; Nematostella ve... 81 1e-13 UniRef50_Q8T101 Cluster: Titin-like protein; n=4; Endopterygota|... 81 2e-13 UniRef50_UPI0000F1EEC5 Cluster: PREDICTED: similar to Immunoglob... 81 2e-13 UniRef50_A2RVD9 Cluster: IP11255p; n=4; Diptera|Rep: IP11255p - ... 81 2e-13 UniRef50_Q9PVD5 Cluster: Netrin receptor unc-5 homolog; n=2; Pet... 81 2e-13 UniRef50_UPI0000F2138A Cluster: PREDICTED: hypothetical protein;... 80 3e-13 UniRef50_UPI0000DB6D94 Cluster: PREDICTED: similar to CG33274-PA... 80 3e-13 UniRef50_UPI00004D30C0 Cluster: Sialoadhesin precursor (Sialic a... 80 3e-13 UniRef50_Q24327 Cluster: Gp160-Dtrk precursor; n=4; Sophophora|R... 80 3e-13 UniRef50_A7RGL4 Cluster: Predicted protein; n=1; Nematostella ve... 80 3e-13 UniRef50_UPI00015B62AD Cluster: PREDICTED: similar to GA13389-PA... 80 4e-13 UniRef50_UPI00015B48D7 Cluster: PREDICTED: similar to lachesin; ... 80 4e-13 UniRef50_Q4S1S8 Cluster: Chromosome undetermined SCAF14764, whol... 80 4e-13 UniRef50_Q7PF94 Cluster: ENSANGP00000024414; n=1; Anopheles gamb... 80 4e-13 UniRef50_Q17AF0 Cluster: Novex-3; n=2; Culicidae|Rep: Novex-3 - ... 80 4e-13 UniRef50_Q501U7 Cluster: Ttnl protein; n=2; Danio rerio|Rep: Ttn... 79 6e-13 UniRef50_Q4THV8 Cluster: Chromosome undetermined SCAF2631, whole... 79 6e-13 UniRef50_Q2WF53 Cluster: Neurotrimin; n=9; Clupeocephala|Rep: Ne... 79 6e-13 UniRef50_A2A344 Cluster: ADAMTS-like 1; n=29; Euteleostomi|Rep: ... 79 6e-13 UniRef50_Q4RU89 Cluster: Chromosome 1 SCAF14995, whole genome sh... 79 7e-13 UniRef50_Q86GD6 Cluster: Projectin; n=1; Procambarus clarkii|Rep... 79 7e-13 UniRef50_Q7PRK4 Cluster: ENSANGP00000000600; n=1; Anopheles gamb... 79 7e-13 UniRef50_UPI0000E4754C Cluster: PREDICTED: similar to DDM36; n=1... 79 1e-12 UniRef50_UPI0000D55EBD Cluster: PREDICTED: similar to CG16857-PA... 79 1e-12 UniRef50_UPI00006A0C09 Cluster: obscurin, cytoskeletal calmoduli... 78 1e-12 UniRef50_Q4T3W5 Cluster: Chromosome undetermined SCAF9901, whole... 78 1e-12 UniRef50_Q4SXT7 Cluster: Chromosome undetermined SCAF12335, whol... 78 1e-12 UniRef50_Q3MHW8 Cluster: PALLD protein; n=7; Euteleostomi|Rep: P... 78 1e-12 UniRef50_Q28939 Cluster: Vascular cell adhesion molecule precurs... 78 1e-12 UniRef50_P17948 Cluster: Vascular endothelial growth factor rece... 78 1e-12 UniRef50_Q14982 Cluster: Opioid-binding protein/cell adhesion mo... 78 1e-12 UniRef50_Q03142 Cluster: Fibroblast growth factor receptor 4 pre... 78 1e-12 UniRef50_UPI00015B4F8B Cluster: PREDICTED: similar to lachesin, ... 78 2e-12 UniRef50_UPI0000F1E7B2 Cluster: PREDICTED: hypothetical protein;... 78 2e-12 UniRef50_UPI0000DBF2C2 Cluster: PTK7 protein tyrosine kinase 7; ... 78 2e-12 UniRef50_Q58EP4 Cluster: LOC572412 protein; n=2; Danio rerio|Rep... 78 2e-12 UniRef50_A5JTW0 Cluster: Kirrel; n=4; Clupeocephala|Rep: Kirrel ... 78 2e-12 UniRef50_Q8WR61 Cluster: Hemolin; n=2; Noctuoidea|Rep: Hemolin -... 78 2e-12 UniRef50_Q7PXZ1 Cluster: ENSANGP00000022061; n=1; Anopheles gamb... 78 2e-12 UniRef50_A7T347 Cluster: Predicted protein; n=7; Nematostella ve... 78 2e-12 UniRef50_Q5W433 Cluster: Sialic-acid binding protein-4 precursor... 77 2e-12 UniRef50_Q59F30 Cluster: Fibroblast growth factor receptor 4 var... 77 2e-12 UniRef50_Q62230 Cluster: Sialoadhesin precursor; n=9; Murinae|Re... 77 2e-12 UniRef50_Q4SLN7 Cluster: Chromosome 15 SCAF14556, whole genome s... 77 3e-12 UniRef50_A7MB72 Cluster: MGC166429 protein; n=4; Tetrapoda|Rep: ... 77 3e-12 UniRef50_A7SJL2 Cluster: Predicted protein; n=1; Nematostella ve... 77 3e-12 UniRef50_Q86TC9 Cluster: Myopalladin; n=20; Amniota|Rep: Myopall... 77 3e-12 UniRef50_Q965M2 Cluster: Putative uncharacterized protein; n=3; ... 77 4e-12 UniRef50_Q7JN85 Cluster: Twitchin; n=6; Bilateria|Rep: Twitchin ... 77 4e-12 UniRef50_A7S4M0 Cluster: Predicted protein; n=2; Nematostella ve... 77 4e-12 UniRef50_P15364 Cluster: Protein amalgam precursor; n=6; melanog... 77 4e-12 UniRef50_UPI0000DB7559 Cluster: PREDICTED: similar to sticks and... 76 5e-12 UniRef50_Q17G58 Cluster: Lachesin; n=3; Culicidae|Rep: Lachesin ... 76 5e-12 UniRef50_Q868Z9 Cluster: Papilin precursor; n=8; cellular organi... 76 5e-12 UniRef50_P43121 Cluster: Cell surface glycoprotein MUC18 precurs... 76 5e-12 UniRef50_Q8N3J6 Cluster: Cell adhesion molecule 2 precursor; n=3... 76 5e-12 UniRef50_UPI0000DB6DA8 Cluster: PREDICTED: similar to CG32387-PB... 76 7e-12 UniRef50_Q16UT3 Cluster: Papilin; n=1; Aedes aegypti|Rep: Papili... 76 7e-12 UniRef50_P06731 Cluster: Carcinoembryonic antigen-related cell a... 76 7e-12 UniRef50_Q7PW77 Cluster: ENSANGP00000005214; n=1; Anopheles gamb... 75 9e-12 UniRef50_A7RT95 Cluster: Predicted protein; n=1; Nematostella ve... 75 9e-12 UniRef50_Q9V787 Cluster: Hibris; n=4; Sophophora|Rep: Hibris - D... 75 1e-11 UniRef50_A7UQ11 Cluster: Putative uncharacterized protein; n=1; ... 75 1e-11 UniRef50_UPI0001556498 Cluster: PREDICTED: similar to obscurin, ... 75 2e-11 UniRef50_UPI0000DB7433 Cluster: PREDICTED: similar to unc-5 CG81... 75 2e-11 UniRef50_Q4T6R9 Cluster: Chromosome undetermined SCAF8634, whole... 75 2e-11 UniRef50_Q4T444 Cluster: Chromosome undetermined SCAF9829, whole... 75 2e-11 UniRef50_Q9VFU7 Cluster: CG14372-PB; n=5; Endopterygota|Rep: CG1... 75 2e-11 UniRef50_Q8IZU9 Cluster: Kin of IRRE-like protein 3 precursor; n... 75 2e-11 UniRef50_Q96J84 Cluster: Kin of IRRE-like protein 1 precursor; n... 75 2e-11 UniRef50_Q95YM9 Cluster: Fibroblast growth factor receptor precu... 75 2e-11 UniRef50_Q8NFZ8 Cluster: Cell adhesion molecule 4 precursor; n=2... 75 2e-11 UniRef50_UPI0000F20798 Cluster: PREDICTED: hypothetical protein;... 74 2e-11 UniRef50_Q8IP70 Cluster: CG31814-PA; n=9; Endopterygota|Rep: CG3... 74 2e-11 UniRef50_Q7PRJ5 Cluster: ENSANGP00000024207; n=3; Endopterygota|... 74 2e-11 UniRef50_UPI0001554C79 Cluster: PREDICTED: hypothetical protein;... 74 3e-11 UniRef50_UPI0000D55B25 Cluster: PREDICTED: similar to CG6669-PA;... 74 3e-11 UniRef50_UPI000051A102 Cluster: PREDICTED: similar to CG31646-PA... 74 3e-11 UniRef50_Q4RFF0 Cluster: Chromosome 8 SCAF15119, whole genome sh... 74 3e-11 UniRef50_Q4RE90 Cluster: Chromosome undetermined SCAF15134, whol... 74 3e-11 UniRef50_Q4RE89 Cluster: Chromosome undetermined SCAF15134, whol... 74 3e-11 UniRef50_Q16XM4 Cluster: Cell adhesion molecule; n=2; Culicidae|... 74 3e-11 UniRef50_Q6UY18 Cluster: Leucine-rich repeat neuronal protein 6D... 74 3e-11 UniRef50_UPI000065F0CA Cluster: Homolog of Homo sapiens "MAM dom... 73 4e-11 UniRef50_UPI000065EECD Cluster: Homolog of Brachydanio rerio "Ob... 73 4e-11 UniRef50_Q6NY23 Cluster: Zgc:64208; n=10; Clupeocephala|Rep: Zgc... 73 4e-11 UniRef50_Q2EGT7 Cluster: Limbic system-associated membrane prote... 73 4e-11 UniRef50_Q9VMN9 Cluster: CG14010-PA; n=2; Diptera|Rep: CG14010-P... 73 4e-11 UniRef50_Q173C9 Cluster: Netrin receptor; n=1; Aedes aegypti|Rep... 73 4e-11 UniRef50_A0NBD2 Cluster: ENSANGP00000031587; n=1; Anopheles gamb... 73 4e-11 UniRef50_Q9W4R3 Cluster: CG32791-PA; n=6; Endopterygota|Rep: CG3... 73 6e-11 UniRef50_Q9VHQ8 Cluster: CG31369-PA; n=8; Endopterygota|Rep: CG3... 73 6e-11 UniRef50_Q13449 Cluster: Limbic system-associated membrane prote... 73 6e-11 UniRef50_UPI00006A03AF Cluster: Sialic acid-binding Ig-like lect... 72 8e-11 UniRef50_UPI000065FE6C Cluster: Homolog of Homo sapiens "Carcino... 72 8e-11 UniRef50_Q5IFI2 Cluster: Gicerin; n=5; Danio rerio|Rep: Gicerin ... 72 8e-11 UniRef50_UPI00015B5C2D Cluster: PREDICTED: similar to lachesin; ... 72 1e-10 UniRef50_UPI00015B5A89 Cluster: PREDICTED: similar to papilin; n... 72 1e-10 UniRef50_UPI0000F2DD14 Cluster: PREDICTED: similar to IGSF4D pro... 72 1e-10 UniRef50_UPI0000D55579 Cluster: PREDICTED: similar to CG14521-PA... 72 1e-10 UniRef50_Q9VMN6 Cluster: CG31646-PA; n=9; Endopterygota|Rep: CG3... 72 1e-10 UniRef50_A7RZ85 Cluster: Predicted protein; n=1; Nematostella ve... 72 1e-10 UniRef50_Q4ACB4 Cluster: Mahya; n=3; Endopterygota|Rep: Mahya - ... 71 1e-10 UniRef50_UPI0000F1E3FB Cluster: PREDICTED: similar to novel immu... 71 2e-10 UniRef50_UPI0000F1DED3 Cluster: PREDICTED: similar to sialic-aci... 71 2e-10 UniRef50_UPI0000E80635 Cluster: PREDICTED: similar to papilin; n... 71 2e-10 UniRef50_Q22040 Cluster: Putative uncharacterized protein SSSD1.... 71 2e-10 UniRef50_A7SZ31 Cluster: Predicted protein; n=1; Nematostella ve... 71 2e-10 UniRef50_UPI0000E472F6 Cluster: PREDICTED: similar to myosin lig... 71 3e-10 UniRef50_Q58QC3 Cluster: Nephrin; n=3; Euteleostomi|Rep: Nephrin... 71 3e-10 UniRef50_Q17HV9 Cluster: Titin; n=5; Endopterygota|Rep: Titin - ... 71 3e-10 UniRef50_UPI00015B62AB Cluster: PREDICTED: similar to CG18255-PA... 70 3e-10 UniRef50_UPI0000D55947 Cluster: PREDICTED: similar to CG33141-PA... 70 3e-10 UniRef50_Q4SI34 Cluster: Chromosome 5 SCAF14581, whole genome sh... 70 3e-10 UniRef50_Q9VM64 Cluster: CG9211-PA; n=8; Sophophora|Rep: CG9211-... 70 3e-10 UniRef50_Q9U3P2 Cluster: Putative uncharacterized protein syg-2;... 70 3e-10 UniRef50_Q61PF2 Cluster: Putative uncharacterized protein CBG075... 70 3e-10 UniRef50_Q17J18 Cluster: Tyrosine-protein kinase; n=4; Endoptery... 70 3e-10 UniRef50_UPI00015B5C00 Cluster: PREDICTED: similar to VEGFR-A sp... 70 4e-10 UniRef50_UPI0000F1D6A2 Cluster: PREDICTED: hypothetical protein;... 70 4e-10 UniRef50_A0A4W4 Cluster: Kilon; n=5; Clupeocephala|Rep: Kilon - ... 70 4e-10 UniRef50_A7S0R0 Cluster: Predicted protein; n=1; Nematostella ve... 70 4e-10 UniRef50_Q9BZZ2 Cluster: Sialoadhesin precursor; n=17; Eutheria|... 70 4e-10 UniRef50_Q8MQ86 Cluster: Putative uncharacterized protein F02G3.... 69 6e-10 UniRef50_Q96LA6 Cluster: Fc receptor-like protein 1; n=19; Euthe... 69 6e-10 UniRef50_Q4S3Q6 Cluster: Chromosome 17 SCAF14747, whole genome s... 69 8e-10 UniRef50_Q16Q42 Cluster: Putative uncharacterized protein; n=1; ... 69 8e-10 UniRef50_A7TBA8 Cluster: Predicted protein; n=1; Nematostella ve... 69 8e-10 UniRef50_A1ZAB1 Cluster: CG8434-PA; n=2; Sophophora|Rep: CG8434-... 69 8e-10 UniRef50_UPI00006A1BAE Cluster: B-cell receptor CD22 precursor (... 69 1e-09 UniRef50_Q26475 Cluster: REGA-1 protein precursor; n=1; Schistoc... 68 1e-09 UniRef50_Q1HPN0 Cluster: Insulin-related peptide binding protein... 68 1e-09 UniRef50_A7T0T0 Cluster: Predicted protein; n=1; Nematostella ve... 68 1e-09 UniRef50_A7RNN5 Cluster: Predicted protein; n=1; Nematostella ve... 68 1e-09 UniRef50_UPI0000DB720F Cluster: PREDICTED: similar to CG14964-PA... 68 2e-09 UniRef50_UPI00004D96E1 Cluster: adlican; n=1; Xenopus tropicalis... 68 2e-09 UniRef50_UPI000066082B Cluster: Homolog of Homo sapiens "CD22 pr... 68 2e-09 UniRef50_Q9VAR6 Cluster: CG14521-PA; n=5; Diptera|Rep: CG14521-P... 68 2e-09 UniRef50_Q6ZNM1 Cluster: FLJ00259 protein; n=16; Amniota|Rep: FL... 68 2e-09 UniRef50_O95428 Cluster: Papilin; n=6; Eutheria|Rep: Papilin - H... 68 2e-09 UniRef50_UPI00004D91EC Cluster: WAP four-disulfide core domain p... 67 2e-09 UniRef50_Q9VZT8 Cluster: CG14964-PA; n=4; Diptera|Rep: CG14964-P... 67 2e-09 UniRef50_UPI00005A3E04 Cluster: PREDICTED: similar to protein ty... 67 3e-09 >UniRef50_Q174G3 Cluster: Roundabout; n=5; Aedes aegypti|Rep: Roundabout - Aedes aegypti (Yellowfever mosquito) Length = 1345 Score = 932 bits (2307), Expect = 0.0 Identities = 479/1042 (45%), Positives = 650/1042 (62%), Gaps = 34/1042 (3%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGLFFL 69 P IIE P+D TV RH+PATLNC+A G P+P I+WYK G L + +HR LPAG LFFL Sbjct: 83 PRIIEHPIDTTVPRHEPATLNCKAEGVPAPTIQWYKDGSLLKIFPGSHRIFLPAGELFFL 142 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 + + R SDAGVYWCEA N G ARSRNATL VAVLRE+FRLEP+S + AQG+TV+LEC Sbjct: 143 KVVNSRRESDAGVYWCEAHNENGVARSRNATLQVAVLREDFRLEPQSTRVAQGETVLLEC 202 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189 PP+G PEP V W+KNGQ L + R+ +VDGGNL IQD RQTD G+YQCIARN G R Sbjct: 203 GPPKGIPEPTVAWRKNGQKLDVESSKRIRVVDGGNLAIQDVRQTDEGQYQCIARNQVGVR 262 Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249 ESA+A LK+H+KP+LI GP D GSSVTFQCRVGGDP+PDVLWRRSA GGNMPL RV Sbjct: 263 ESAVAFLKVHVKPFLIRGPHDSTIVEGSSVTFQCRVGGDPMPDVLWRRSASGGNMPLDRV 322 Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309 +L+D SLRL+NV+L DEGEYSCEA+N+VG +SA+G L V+ PP + + P VE+ + Sbjct: 323 HILEDRSLRLENVVLDDEGEYSCEADNAVGTISATGTLNVHSPPHLVIRPVQQVVEAPHD 382 Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369 A F C + GRP+PT FWS+EGNRT+IFPG D++ + +G++VLTI T K D+ Sbjct: 383 ATFECRSEGRPKPTTFWSIEGNRTLIFPGSKFDRFETSTTVEGLSVLTIPQTTKADNGLI 442 Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429 +VCS+VN GS VR +LTV S DDRPPPII GPSNQTLP+ S+ PC A+ P PII Sbjct: 443 VVCSSVNSVGSISVRARLTVASQDDRPPPIIILGPSNQTLPLGSVVALPCKAVGNPNPII 502 Query: 430 AWYFEGEALIQNHRRNVTNDGTLVLKDLDKS-DSGTYTCVASSRHGKYVWSGALLVDSPI 488 +WY +G +I + R N+T++GTL++ DLDKS D G YTCVASSR GK WS L ++SP Sbjct: 503 SWYLDGNPVINSERTNMTDNGTLIIHDLDKSTDQGLYTCVASSRSGKATWSAYLRLESPT 562 Query: 489 NPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETL 548 NPNIHFFRA + S+ P P KP NVT++S+T+SW + K G+S I GY +EVF+ + Sbjct: 563 NPNIHFFRAHEPSAFPTAPGKPQVVNVTNSSITISWLPSIKSGASDINGYLIEVFATDM- 621 Query: 549 SGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVG 608 ++GW+ I ++ T Y + ++Y FIVR EN GL PS +SD VT+G Sbjct: 622 --------AKGWIPIPYKLSSTSYTYSPVTADVSYTFIVRAENDQGLGIPSLMSDPVTIG 673 Query: 609 DDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYF 668 D N G + N +E + + + +V L+EA DS +++L WEI+N Y+EG +IY Sbjct: 674 RDFN---HGEDI-NLSEAQATLSSGSVVNLLEANASDSSSVRLAWEIVNGQYVEGFYIYS 729 Query: 669 RPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLD 728 R + N Y+ T+LH S I L KYT+YEFFL+PF+K EG+PSNSR TL+ Sbjct: 730 RQI-NSNGTYKTLTVLHGGGASACTINGLEKYTEYEFFLVPFFKTIEGRPSNSRTTWTLE 788 Query: 729 DVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTT 788 DVP P+N+E +LNT+ V+LKW PP NG + Y++++ D+ N S V N T Sbjct: 789 DVPSASPVNMEAVLLNTSAVYLKWEPPANHSLNGKLKNYHIIIRGYDI-HNISKVLTNMT 847 Query: 789 VH-QATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDL-LSRYPMNG 846 V + L++ NL++GV+YSV IAA T +G+GP+S +D + LD +RYP+N Sbjct: 848 VDGDSPKLLLANLSAGVTYSVSIAASTRVGMGPYSAPSILRLDPHTKRLDQGYTRYPINH 907 Query: 847 EVSIVAGDFVMETWFYFLIGAIVLFKIIVIAGIIYVRKYNIFAKKSALPNIYDSNGTSLV 906 + S D + +TWF L+G+I+ + + + R+ F K S+L N++ ++ V Sbjct: 908 DYS---HDILTQTWFIILLGSIIAIIVFLFGATVIFRRIQ-FMKHSSLNNMHGNHAIGTV 963 Query: 907 TQMNIKAAVSLSHPLTSCYNKNTVTKTESLLWMENQPGVCLSGNQTSQSKEKTNFEYDKV 966 + + L+ V + S + E N + +Y+++ Sbjct: 964 RKF---PTLPLNPNGVWIDPGGGVWRQASEITKEAITDYAAVSNAPTLPLP----DYERL 1016 Query: 967 TH-QLPEYAEVT--SARANEWNTNKTATSPAAYASVTLVANTRQCVSSLGWFPPGGKNVD 1023 + +P+YAEV S+ N+ + + + AYAS TLV + +S G G + Sbjct: 1017 SPLNMPDYAEVAGCSSFKNDLGGSPSYDNYGAYASTTLVGRSIGNAASNGTSVASGAPMF 1076 Query: 1024 TFDNRYGADEELYPASNGGYYN 1045 + +Y A +YN Sbjct: 1077 AQQQNQFDGKNVYSAPTSCHYN 1098 >UniRef50_UPI0000D56E5C Cluster: PREDICTED: similar to CG5423-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG5423-PA - Tribolium castaneum Length = 1136 Score = 925 bits (2290), Expect = 0.0 Identities = 479/1055 (45%), Positives = 649/1055 (61%), Gaps = 59/1055 (5%) Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-----THRSILP 62 S + P I E P+D TVARH+PATLNC A G P P I W+K G+ + + +HR +LP Sbjct: 67 SQQPPRITEHPVDTTVARHEPATLNCHASGEPEPTITWFKDGMTLRTAPQDARSHRVLLP 126 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122 AG LFFLR R SDAGVYWCEA+N+ G ARSRNATL VAVLR+EFRLEP+S + A G Sbjct: 127 AGNLFFLRVVQSRKESDAGVYWCEASNALGKARSRNATLTVAVLRDEFRLEPQSTRVAAG 186 Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182 + +V+EC PPRG+PEP V+W+K+G TL +G R+ LVDG NL I D + +D GRYQC+A Sbjct: 187 EDIVMECAPPRGTPEPQVFWRKDGHTLEVEG--RLKLVDGSNLAITDTKPSDDGRYQCVA 244 Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242 +N AG RESA+A LK+++KP+LI PED A GS+V F C VGGDPLPDVLWRR+A GG Sbjct: 245 KNTAGVRESAVAILKVYVKPFLIKPPEDKTALVGSTVDFPCAVGGDPLPDVLWRRNAAGG 304 Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302 MPLGRV+VL+D +LRL+ + L D+G Y+CEA+N GA++A+ LTV+ PP++ P + Sbjct: 305 TMPLGRVRVLEDRTLRLERITLLDQGRYTCEADNYAGAITATALLTVHAPPTLTTRPLAQ 364 Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362 VES F C G P+P +FWS EG+RT+I+PG S Y T V +G + LT+ Sbjct: 365 TVESNRDVSFHCNVEGSPKPFIFWSFEGDRTLIYPGTSTGNYQVTTV-EGKSTLTLKQAQ 423 Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422 +S I+CSAVN AGS+ R +LTVTS ++ PPP+I GP NQTLPI S+A C A Sbjct: 424 PQNSGTVIICSAVNAAGSASTRTRLTVTSREEHPPPVIIRGPVNQTLPINSVAFLSCEAS 483 Query: 423 CTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482 P P+I+WY E + +R N TN G + + +L K DSG YTCVASSR GK WSG L Sbjct: 484 GNPTPVISWYKENHPVTSTNRINTTNPGLVEIHNLQKDDSGLYTCVASSRSGKATWSGHL 543 Query: 483 LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEV 542 LV++P NPNI+FF+A + LPGPP++P N ++ SVT++W QNNKIGSSS+LGYQ+E+ Sbjct: 544 LVENPKNPNINFFKAPEAIMLPGPPSRPHALNQSEGSVTITWGQNNKIGSSSLLGYQIEL 603 Query: 543 FSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602 F RE TP W V+ARRV Y L P + Y F+VR EN HGL PS +S Sbjct: 604 FGREE---GVTPT----WTVVARRVQGPTYTQHLLSPSVPYTFLVRAENGHGLGPPSQLS 656 Query: 603 DSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLE 662 D + VG D+ W V+ +E R +++ IV L EA P+ S IKL+WEIL+ Y+E Sbjct: 657 DIIIVGPDTAQNWGNPEVTVLSEARASLVKGDIVRLSEAIPVLSTAIKLVWEILDAQYVE 716 Query: 663 GLFIYFRPLD---NITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPS 719 GL+IY+ LD ++ Y M T+LH+ S F + +L K+++YEFFL+PFYK EG+PS Sbjct: 717 GLYIYYVTLDGPSDLPKPYSMLTVLHTGGASSFTVNNLAKWSRYEFFLVPFYKTVEGQPS 776 Query: 720 NSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPAN 779 NSR +TL+DVP P ++E +LN+T V+LKW PP + NG + GY + ++ AN Sbjct: 777 NSRTVRTLEDVPVEAPTSMEALLLNSTAVYLKWKPPPSETLNGDLQGYKI-----EIKAN 831 Query: 780 KSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLL 839 + TV +L++ NLT+GV+Y+V++AA T GLGPFS +D S D Sbjct: 832 GTGTTDTVTVGTTPTLLLGNLTAGVAYTVKVAAMTRAGLGPFSSAAILRLDPASRHNDHH 891 Query: 840 SRYPMNGEVSIVAGDFVMETWFYFLIGAIVLFKIIVIAGIIYVRKYNIFAKKSALPNIYD 899 + P + + +GDF+ ETWF L+ ++V +++ ++ VR+ + KK+ P+ Sbjct: 892 HQKP----IDMQSGDFITETWFMALLISMVSVMVLLFGAMLLVRRRQMLTKKTLTPS--R 945 Query: 900 SNGTSLVTQMNIKAAVSLSHPLTSCYNKNTVTKTESLLWMENQPGVCLSGNQTSQSKEKT 959 SNG L T + K L + + + S L E + + SK Sbjct: 946 SNGAVLTTPLASKTETPLWLDKDALPDYSNSLPEYSKLTPEVNLHLNPRPDHLDCSK-YM 1004 Query: 960 NFEYDKVTHQLPEYAEVTSARANEWNTNKTATSPAAYASVTLVANTRQCVSSLGWFPPGG 1019 E + + L +YAEV +++ TSPA YA+ TLV R+ V W Sbjct: 1005 QVEKEYASPNLADYAEVEASQ---------VTSPAPYATTTLVTGGRRMV----W----- 1046 Query: 1020 KNVDTFDNRYGADEELYPASNGGYYNRNVYSEKYF 1054 +E YP+ NGGYYNR VYS+ YF Sbjct: 1047 -----------VEEPPYPSHNGGYYNRKVYSDSYF 1070 >UniRef50_Q9GPP6 Cluster: Roundabout 3; n=4; Diptera|Rep: Roundabout 3 - Drosophila melanogaster (Fruit fly) Length = 1342 Score = 880 bits (2178), Expect = 0.0 Identities = 434/907 (47%), Positives = 596/907 (65%), Gaps = 28/907 (3%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV--LVVSDTHRSILPAGGLFFL 69 P I+E P+D TV RH+PATLNC+A GSP+P I+WYK GV ++ +HR LPAGGLFFL Sbjct: 23 PRIVEHPIDTTVPRHEPATLNCKAEGSPTPTIQWYKDGVPLKILPGSHRITLPAGGLFFL 82 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 + + R +DAG+YWCEA N G ARSRNATL VAVLR+EFRLEP++ + AQGDT +LEC Sbjct: 83 KVVNSRRETDAGIYWCEAKNELGVARSRNATLQVAVLRDEFRLEPQNTRIAQGDTALLEC 142 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189 PRG PEP V WKK GQ L +G R+ +VDGGNL IQDARQTD G+YQCIA+N G R Sbjct: 143 AAPRGIPEPTVTWKKGGQKLDLEGSKRVRIVDGGNLAIQDARQTDEGQYQCIAKNPVGVR 202 Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249 ES++ATLK+H+KPY+I GP D G+SVTF CRVGGDP+PDVLW R+A GGNMPL RV Sbjct: 203 ESSLATLKVHVKPYIIRGPHDQTVLEGASVTFPCRVGGDPMPDVLWLRTASGGNMPLDRV 262 Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309 VL+D SLRL+ V +ADEGEYSCEA+N VGA++A G LTVY PP P S +VE G Sbjct: 263 SVLEDRSLRLERVTIADEGEYSCEADNVVGAITAMGTLTVYAPPKFIQRPASKSVELGAD 322 Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGM-SRDKYHATAVFDGVTVLTINDTDKNDSRN 368 F C A G P+PT+FW+++ N T+IFPG D++H+ +G ++LT+ + D Sbjct: 323 TSFECRAIGNPKPTIFWTIKNNSTLIFPGAPPLDRFHSLNTEEGHSILTLTRFQRTDKDL 382 Query: 369 TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428 I+C+A+N S R +L++ S +DRPPPII +GP NQTLPIKS+A C AI P P Sbjct: 383 VILCNAMNEVASITSRVQLSLDSQEDRPPPIIISGPVNQTLPIKSLATLQCKAIGLPSPT 442 Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDK-SDSGTYTCVASSRHGKYVWSGALLVDSP 487 I+WY +G + + + N+T G L++ DLD+ D G YTCVASSR GK WSG L ++ P Sbjct: 443 ISWYRDGIPVQPSSKLNITTSGDLIISDLDRQQDQGLYTCVASSRAGKSTWSGFLRIELP 502 Query: 488 INPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRET 547 NPNI F+RA + + P P +P N T +++T+ W ++K G+SS LGY VE++ Sbjct: 503 TNPNIKFYRAPEQTKCPSAPGQPKILNATASALTIVWPTSDKAGASSFLGYSVEMY---- 558 Query: 548 LSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVT- 606 SR W+ IA R+ + + V+SL G YMFIVR ENS G S PSP+S+ +T Sbjct: 559 -----CTNQSRTWIPIASRLSEPIFTVESLTQGAAYMFIVRAENSLGFSPPSPISEPITA 613 Query: 607 ---VGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEG 663 VG S GT ++ + + +VEL+EA DS T +L W+I + Y+EG Sbjct: 614 GKLVGVRDGSESTGTSQLLLSDVETLLQANDVVELLEANASDSTTARLSWDIDSGQYIEG 673 Query: 664 LFIYFRPLDNITIEYEMKTILHSND-VSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSR 722 ++Y R L + EY+M T+L+ +S + L K + YEFFL+PFYK GKPSNSR Sbjct: 674 FYLYARELH--SSEYKMVTLLNKGQGLSSCTVPGLAKASTYEFFLVPFYKSIVGKPSNSR 731 Query: 723 VAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPE-LQLQNGIITGYNVVVNWLDVPANKS 781 +TL+DVP+ PP +E N T+V LKW PP+ + +NGI+T YNVVV LDV N + Sbjct: 732 RMRTLEDVPEAPPYGMEAIQFNRTSVFLKWLPPQPNRTRNGILTSYNVVVKGLDV-HNTT 790 Query: 782 MVAINTTVHQAT-SLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDL-L 839 + N T+ AT +L++ NLT+GV+Y + +AA T +G+GPFS+ ID+R+ LD Sbjct: 791 RIFKNMTIDAATPTLLLANLTTGVTYYIAVAAATRVGVGPFSKPAVLRIDARTQSLDTGY 850 Query: 840 SRYPMNGEVSIVAGDFVMETWFYFLIGAIVLFKIIVIAGIIYVRKYNIFAKKSALPNIYD 899 +RYP++ + +A DF+ +TWF L+G+I+ + ++ ++ ++Y F K+++L +++ Sbjct: 851 TRYPISRD---IADDFLTQTWFIVLLGSIIAIIVFLLGALVLFKRYQ-FIKQTSLGSLHG 906 Query: 900 SNGTSLV 906 ++ V Sbjct: 907 NHAIGTV 913 Score = 58.0 bits (134), Expect = 1e-06 Identities = 50/189 (26%), Positives = 76/189 (40%), Gaps = 16/189 (8%) Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 PP I P V A C A G P PT+ W +G I PG R T Sbjct: 22 PPRIVEHPIDTTVPRHEPATLNCKAEGSPTPTIQWYKDGVPLKILPGSHR----ITLPAG 77 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG---KLTVTSDDDRPPPIITNGPSNQT 408 G+ L + ++ + C A N G + R ++ V D+ R P N Sbjct: 78 GLFFLKVVNSRRETDAGIYWCEAKNELGVARSRNATLQVAVLRDEFRLE------PQNTR 131 Query: 409 LPIKSMAVFPCTA-ICTPEPIIAWYFEGEAL-IQNHRR-NVTNDGTLVLKDLDKSDSGTY 465 + A+ C A PEP + W G+ L ++ +R + + G L ++D ++D G Y Sbjct: 132 IAQGDTALLECAAPRGIPEPTVTWKKGGQKLDLEGSKRVRIVDGGNLAIQDARQTDEGQY 191 Query: 466 TCVASSRHG 474 C+A + G Sbjct: 192 QCIAKNPVG 200 >UniRef50_Q9VQ08 Cluster: CG5481-PA; n=6; Diptera|Rep: CG5481-PA - Drosophila melanogaster (Fruit fly) Length = 1463 Score = 722 bits (1784), Expect = 0.0 Identities = 343/693 (49%), Positives = 469/693 (67%), Gaps = 19/693 (2%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT--HRSILPAGGL 66 GE P IIE P+D TV ++ P T NC+A G+P+P I+W+K G + +DT HR +LPAGGL Sbjct: 88 GENPRIIEHPMDTTVPKNDPFTFNCQAEGNPTPTIQWFKDGRELKTDTGSHRIMLPAGGL 147 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126 FFL+ H R SDAG YWCEA N +G ARSRNATL VA LR+EFRLEP + + AQG+ + Sbjct: 148 FFLKVIHSRRESDAGTYWCEAKNEFGVARSRNATLQVAFLRDEFRLEPANTRVAQGEVAL 207 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186 +EC PRGSPEP + W+KNGQTL G+ R+ +VDGGNL IQ+ARQ+D GRYQC+ +N Sbjct: 208 MECGAPRGSPEPQISWRKNGQTLNLVGNKRIRIVDGGNLAIQEARQSDDGRYQCVVKNVV 267 Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 GTRESA A LK+H++P+LI GP++ A GSSV FQCR+GGDPLPDVLWRR+A GGNMPL Sbjct: 268 GTRESATAFLKVHVRPFLIRGPQNQTAVVGSSVVFQCRIGGDPLPDVLWRRTASGGNMPL 327 Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306 RV VL+D SL+LD+V L D GEY+CEA+N+VG ++A+G LTV+ PP + P + VE Sbjct: 328 RRVHVLEDRSLKLDDVTLEDMGEYTCEADNAVGGITATGILTVHAPPKFVIRPKNQLVEI 387 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 G+ F C A G P PT++WSVEGN +++ PG + T +G +VL+I + DS Sbjct: 388 GDEVLFECQANGHPRPTLYWSVEGNSSLLLPGYRDGRMEVTLTPEGRSVLSIARFAREDS 447 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426 + C+A+N GS R ++V + + PPPII GP NQTLP+KS+ V PC + TP Sbjct: 448 GKVVTCNALNAVGSVSSRTVVSVDTQFELPPPIIEQGPVNQTLPVKSIVVLPCRTLGTPV 507 Query: 427 PIIAWYFEGEAL-IQNH-RRNVTNDGTLVLKDLDK-SDSGTYTCVASSRHGKYVWSGALL 483 P ++WY +G + +Q H RRN+++ G L + DL + D G YTCVAS+R+GK WSG L Sbjct: 508 PQVSWYLDGIPIDVQEHERRNLSDAGALTISDLQRHEDEGLYTCVASNRNGKSSWSGYLR 567 Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543 +D+P NPNI FFRA ++S+ PGPP KP + SVTLSW+++NK+G SS++GY +E+F Sbjct: 568 LDTPTNPNIKFFRAPELSTYPGPPGKPQMVEKGENSVTLSWTRSNKVGGSSLVGYVIEMF 627 Query: 544 SRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603 + N T GWV + RV T + L+PG+ Y F++R ENSHGLS PSP+S+ Sbjct: 628 GK-----NETD----GWVAVGTRVQNTTFTQTGLLPGVNYFFLIRAENSHGLSLPSPMSE 678 Query: 604 SVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEG 663 +TVG + + +G+ S E R ++L+ +VEL A+ +DS ++KL W+I+N Y+EG Sbjct: 679 PITVG----TRYFNSGLDLS-EARASLLSGDVVELSNASVVDSTSMKLTWQIINGKYVEG 733 Query: 664 LFIYFRPLDNITIEYEMKTILHSNDVSGFEITS 696 ++Y R L N + ++N + G TS Sbjct: 734 FYVYARQLPNPIVNNPAPVTSNTNPLLGSTSTS 766 Score = 178 bits (434), Expect = 7e-43 Identities = 92/239 (38%), Positives = 143/239 (59%), Gaps = 7/239 (2%) Query: 674 ITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDG 733 + +Y M TIL+ S IT L +YT YEFF++PFYK EGKPSNSR+A+TL+DVP Sbjct: 804 LNTKYRMLTILNGGGASSCTITGLVQYTLYEFFIVPFYKSVEGKPSNSRIARTLEDVPSE 863 Query: 734 PPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT 793 P +E +LN++ V LKW PEL+ ++G++ Y+V+V +D N S + N T+ A+ Sbjct: 864 APYGMEALLLNSSAVFLKWKAPELKDRHGVLLNYHVIVRGIDTAHNFSRILTNVTIDAAS 923 Query: 794 -SLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLD--LLSRYPMNGEVSI 850 +L++ NLT GV Y+V +AA G+GP+ +D + LD + RYP+N + Sbjct: 924 PTLVLANLTEGVMYTVGVAAGNNAGVGPYCVPATLRLDPITKRLDPFINQRYPINQDH-- 981 Query: 851 VAGDFVMETWFYFLIGAIVLFKIIVIAGIIYVRKYNIFAKKSALPNIYDSNGTSLVTQM 909 D + + WF L+GAI+ ++ +++V++ ++ K+SAL N N TS V +M Sbjct: 982 -VNDVLTQPWFIILLGAILAVLMLSFGAMVFVKRKHMMMKQSAL-NTMRGNHTSDVLKM 1038 >UniRef50_UPI0000D55AA5 Cluster: PREDICTED: similar to CG13521-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG13521-PA, isoform A - Tribolium castaneum Length = 1073 Score = 675 bits (1667), Expect = 0.0 Identities = 378/907 (41%), Positives = 523/907 (57%), Gaps = 60/907 (6%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-----THRSILPAGG 65 +P I E P D+ VA+++P TLNC+A G P P I W+K G V + +HR +LPAG Sbjct: 18 SPRITEHPSDIIVAKNEPVTLNCKAEGRPEPTIEWFKDGEPVKTSPTDNKSHRVLLPAGS 77 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 LFFLR + + DAGVYWC A N+ G+A SRNATL VAVLR+EFR+ P + A G+T Sbjct: 78 LFFLRTMNSKKEQDAGVYWCVARNTAGSAVSRNATLQVAVLRDEFRVMPSDTRVAAGETA 137 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 +L+C PRG PEPN+ W+K+G+ L DG R+ +VDGGNL+I D RQ D GRYQC+A N Sbjct: 138 LLQCGAPRGHPEPNLMWRKDGEVLEVDG-RRIRIVDGGNLMISDVRQHDEGRYQCVAHNL 196 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 G+RE+ L +H+KP+ P+DVVA G V FQC V G+P+P+VLWRR G MP Sbjct: 197 VGSRETPPVMLTVHVKPFFNKEPQDVVALLGKRVVFQCAVDGEPVPNVLWRRE--DGKMP 254 Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305 +GR ++LDD SL +DNV +DEG Y C AEN VG+++A L V PP+ P V Sbjct: 255 IGRARILDDKSLLIDNVQTSDEGIYICAAENVVGSITAKASLVVNSPPTFIEKPRDQKVS 314 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365 V F C+ATG P P++FW+ EG++ ++FP S H A G L I + D Sbjct: 315 LNGVVEFHCSATGNPPPSVFWTKEGSQMLMFPDNSYGHMHVNA--HG--TLRIQGVQRED 370 Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425 + +VCSA++ AGSS VR L VTS D PPPII GP+NQTLP+ SM C A +P Sbjct: 371 A-GFLVCSALSVAGSSSVRAFLQVTSVADLPPPIIQIGPANQTLPLHSMVTLHCKA-SSP 428 Query: 426 E---PIIAWYFEGEALIQNH---RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479 E P I W +G+ L + R ++ GTL + DL DSG YTC A S G+ WS Sbjct: 429 EGEQPKIRWSKDGKVLQEERLPDRYTISETGTLDIDDLRLDDSGLYTCSAISESGESSWS 488 Query: 480 GALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQ 539 +L V + +H R+ D S+ P P +P N T++S+TL+W + G ++GY Sbjct: 489 ASLSVVEGSSALLH--RSPDPSTFPKAPNQPRILNATESSITLAWDDGPEAG---LVGYT 543 Query: 540 VEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599 VE +S P GWV+ A RV + VV+ L P +YMFIVR EN+HGLS S Sbjct: 544 VEYWS---------PDLQTGWVIAAHRV-SNYIVVRELKPDSSYMFIVRAENAHGLSPAS 593 Query: 600 PVSDSVTVGDDSNSLWEGTGVSNS-TEYRNNILTDHIVELIEATPIDSKTIKLMWEILNF 658 PVS + +L VS S + L+ +VEL +A P S ++KL W + Sbjct: 594 PVSSI------ARTLANSRAVSGSELDTARTALSTKLVELRDARPQSSSSVKLTWSLAAL 647 Query: 659 YYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKP 718 Y+EGL+I FR L + Y + T+L S + +++L+K+TKYEFF+ PFYK EG+P Sbjct: 648 DYIEGLYIRFRELSGGSHNYNILTVLDVQTKS-YTVSNLKKFTKYEFFIAPFYKSVEGQP 706 Query: 719 SNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPA 778 SNSRVAQTL+DVP PP + + N T ++WSPP Q NGII GY + + Sbjct: 707 SNSRVAQTLEDVPSAPPDGVTAGVFNDTAGWVRWSPPPPQHHNGIIIGYKIQIRG---SI 763 Query: 779 NKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDL 838 +S+ ++T TS++++NLTSG SY+ +IAA T G GP+S +V R+ Sbjct: 764 TRSLTVNSST----TSVLISNLTSGGSYNARIAALTHAGQGPYSNQVPLLTAPRAQSPRT 819 Query: 839 LSRYPMNGEVSIVAGDFVMETWFYFLIGAIVLFKIIVIAGIIYVRKYNIFAKKSALPNIY 898 L + V +TWF L+ +L +++ G++Y++K +K+ N+ Sbjct: 820 LGPFV----------PLVQQTWFVVLLATAILAILVITGGLLYLKKRQSLSKQLGHLNVP 869 Query: 899 DSNGTSL 905 N + L Sbjct: 870 VVNASQL 876 Score = 36.3 bits (80), Expect = 5.1 Identities = 28/102 (27%), Positives = 43/102 (42%), Gaps = 9/102 (8%) Query: 391 SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL------IQNHRR 444 +D P IT PS+ + C A PEP I W+ +GE + ++HR Sbjct: 12 NDSQFRSPRITEHPSDIIVAKNEPVTLNCKAEGRPEPTIEWFKDGEPVKTSPTDNKSHRV 71 Query: 445 NVTNDGTLVLKDLD---KSDSGTYTCVASSRHGKYVWSGALL 483 + L+ ++ + D+G Y CVA + G V A L Sbjct: 72 LLPAGSLFFLRTMNSKKEQDAGVYWCVARNTAGSAVSRNATL 113 >UniRef50_Q9W213 Cluster: CG13521-PB, isoform B; n=5; Sophophora|Rep: CG13521-PB, isoform B - Drosophila melanogaster (Fruit fly) Length = 1429 Score = 634 bits (1566), Expect = e-180 Identities = 337/838 (40%), Positives = 494/838 (58%), Gaps = 45/838 (5%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD---THRSILPAGGL 66 ++P IIE P D+ V +++PATLNC+ G P P I W+K G V ++ +HR G L Sbjct: 88 QSPRIIEHPTDLVVKKNEPATLNCKVEGKPEPTIEWFKDGEPVSTNEKKSHRVQFKDGAL 147 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126 FF R G+ D G YWC A N G A SR+A+L +AVLR++FR+EP+ + A+G+T + Sbjct: 148 FFYRTMQGKKEQDGGEYWCVAKNRVGQAVSRHASLQIAVLRDDFRVEPKDTRVAKGETAL 207 Query: 127 LECLPPRGSPEPNVYWKKNG------QTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180 LEC PP+G PEP + W K+G + + F SR+ +VDGGNL+I + D G Y+C Sbjct: 208 LECGPPKGIPEPTLIWIKDGVPLDDLKAMSFGASSRVRIVDGGNLLISNVEPIDEGNYKC 267 Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 IA+N GTRES+ A L + +KPY + P+D V G + TF C VGGDP P VLW++ G Sbjct: 268 IAQNLVGTRESSYAKLIVQVKPYFMKEPKDQVMLYGQTATFHCSVGGDPPPKVLWKKEEG 327 Query: 241 GGNMPLGRVKVL-DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299 N+P+ R ++L D+ SL + N+ DEG Y CEA N+VG +SA L V+ PP+ P Sbjct: 328 --NIPVSRARILHDEKSLEISNITPTDEGTYVCEAHNNVGQISARASLIVHAPPNFTKRP 385 Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359 ++ V V + C A+G P P++FW+ EG T++FP S + H A DG L I Sbjct: 386 SNKKVGLNGVVQLPCMASGNPPPSVFWTKEGVSTLMFPNSSHGRQHVAA--DGT--LQIT 441 Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419 D + D VCSA + SS VR L V+S D+RPPPII GP+NQTLP S+A PC Sbjct: 442 DVRQEDE-GYYVCSAFSVVDSSTVRVFLQVSSLDERPPPIIQIGPANQTLPKGSVATLPC 500 Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479 A P P I W+ +G A+ +R ++ +L + DL SDSGTYTC AS G+ W+ Sbjct: 501 RATGNPSPRIKWFHDGHAVQAGNRYSIIQGSSLRVDDLQLSDSGTYTCTASGERGETSWA 560 Query: 480 GALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN-NKIGS-SSILG 537 L V+ P + ++H RAAD S+ P PP P NV+ TS++L W+++ K G+ I+G Sbjct: 561 ATLTVEKPGSTSLH--RAADPSTYPAPPGTPKVLNVSRTSISLRWAKSQEKPGAVGPIIG 618 Query: 538 YQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSG 597 Y VE FS P GW+V A+RV T + L PG +Y+F+VR EN+ G+S Sbjct: 619 YTVEYFS---------PDLQTGWIVAAQRVGDTQVTISGLTPGTSYVFLVRAENTQGISV 669 Query: 598 PSPVSDSV-TVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEI- 655 PS +S+++ T+ D ++ +N +LT VELI+A+ I++ ++L W + Sbjct: 670 PSGLSNTIKTIEADFDA-----ASANDLSAARTLLTGKSVELIDASAINASAVRLEWMLH 724 Query: 656 --LNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKK 713 + Y+EGL I+++ + +Y T++ ++ F + +L+KYTKYEFFL PF++ Sbjct: 725 VSADEKYVEGLRIHYKDASVPSAQYHSITVMDAS-AESFVVGNLKKYTKYEFFLTPFFET 783 Query: 714 FEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNW 773 EG+PSNS+ A T +DVP PP NI++ + N T ++W+PP Q NG + GY + V+ Sbjct: 784 IEGQPSNSKTALTYEDVPSAPPDNIQIGMYNQTAGWVRWTPPPSQHHNGNLYGYKIEVS- 842 Query: 774 LDVPANKSMVAINTTVH-QATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNID 830 N V N T++ TS+++ NLT+G YSV++ + T G GP+S+ + +D Sbjct: 843 ---AGNTMKVLANMTLNATTTSVLLNNLTTGAVYSVRLNSFTKAGDGPYSKPISLFMD 897 Score = 50.8 bits (116), Expect = 2e-04 Identities = 52/208 (25%), Positives = 79/208 (37%), Gaps = 23/208 (11%) Query: 290 YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349 Y P I P + V+ A C G+PEPT+ W +G + K H Sbjct: 87 YQSPRIIEHPTDLVVKKNEPATLNCKVEGKPEPTIEWFKDGEPV----STNEKKSHRVQF 142 Query: 350 FDGVTVL--TINDTDKNDSRNTIVCSAVNYAGSSFVRG---KLTVTSDDDRPPPIITNGP 404 DG T+ + D C A N G + R ++ V DD R P T Sbjct: 143 KDGALFFYRTMQGKKEQDG-GEYWCVAKNRVGQAVSRHASLQIAVLRDDFRVEPKDTRVA 201 Query: 405 SNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ--------NHRRNVTNDGTLVLKD 456 +T ++ P I PEP + W +G L + R + + G L++ + Sbjct: 202 KGETALLE---CGPPKGI--PEPTLIWIKDGVPLDDLKAMSFGASSRVRIVDGGNLLISN 256 Query: 457 LDKSDSGTYTCVASSRHGKYVWSGALLV 484 ++ D G Y C+A + G S A L+ Sbjct: 257 VEPIDEGNYKCIAQNLVGTRESSYAKLI 284 >UniRef50_Q17BD3 Cluster: Roundabout 1; n=3; Culicidae|Rep: Roundabout 1 - Aedes aegypti (Yellowfever mosquito) Length = 1231 Score = 617 bits (1525), Expect = e-175 Identities = 337/901 (37%), Positives = 502/901 (55%), Gaps = 44/901 (4%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I E P DV V ++ P TLNC+A G P P IRWYK G V + +LP+G LFFLR Sbjct: 51 PRITEHPSDVLVPKNDPVTLNCKAEGKPEPEIRWYKDGEPVKFTPNHVLLPSGSLFFLRT 110 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131 H + D GVYWC A+N+ GT SRNATL +AVLR+EFR+EP+ + A G+T +LEC Sbjct: 111 VHSKKEQDGGVYWCVASNAAGTVNSRNATLQIAVLRDEFRVEPKDTRVAAGETALLECGA 170 Query: 132 PRGSPEPNVYWKKNGQTLLFDG----------DSRMHLVDGGNLVIQDARQTDAGRYQCI 181 P+G+PEP + W+K+ L D +R+ +VDGGNL+I D R TD GRYQCI Sbjct: 171 PKGNPEPTISWRKDEIMLELDDFRPASASGKEPARVRIVDGGNLLISDVRPTDEGRYQCI 230 Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241 A+N G+RES L + +KPY I P D+ G V FQC VGGDP P +LW++ Sbjct: 231 AQNMVGSRESGSGKLTVQVKPYFINEPTDITVLVGQRVQFQCTVGGDPHPQILWKKE--N 288 Query: 242 GNMPLGRVKVL-DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300 G++P+GR ++L +D SL + NV D+G Y CEA NSVG ++A L V P+ + P Sbjct: 289 GHIPVGRAEILEEDRSLVIKNVAQDDQGIYICEAHNSVGQINAKAQLVVNSSPTFIIKPQ 348 Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360 VA F CTA+G P P++FW+ EG++T++FP + H ++ G L + Sbjct: 349 DQRTNLNGVATFKCTASGNPPPSVFWTKEGSQTLMFPNNTYGNIHISS--QG--SLQVRG 404 Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD-DDRPPPIITNGPSNQTLPIKSMAVFPC 419 K D VCSA++ AGS+ R L VTS D PPP++ PSN TLP S+A+ PC Sbjct: 405 AQKEDD-GYFVCSALSVAGSTTSRAYLQVTSSFDSSPPPVLQEVPSNLTLPRGSIAMLPC 463 Query: 420 TAICTPEPIIAWYFEG-EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVW 478 P I W + R ++ GTL + D+ DSG Y+CVA S G+ W Sbjct: 464 RGSGPTSPKIYWKKNATDITALGPRFSIVQGGTLKIDDIQPEDSGWYSCVAYSEKGETSW 523 Query: 479 SGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGY 538 S L V+ ++ + R+ LP P+ P N+T+++VTL W+ KIG Sbjct: 524 SAFLQVEKNLSTMLP--RSGSPELLPVAPSIPKAVNITNSNVTLMWT---KIGGGGEDSL 578 Query: 539 QVEVFSRET---LSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGL 595 Q ++++ L +P +GW + A RV + +L P +Y+F+VR EN++G Sbjct: 579 QEKLWNNPVSGYLVEYYSPDEKKGW-IRAIRVPGNTATITNLSPSTSYIFVVRAENAYGY 637 Query: 596 SGPSPVSDSV-TVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWE 654 S PSP+S+ + T+ D +G + E +L I+EL++A I S +++L W+ Sbjct: 638 SAPSPLSNLIRTLSAD-----DGVTMPEELEAARMVLNGKILELVDAVAISSTSVRLEWQ 692 Query: 655 I---LNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFY 711 + Y+EGL++ +R L + +Y M TI +N IT+L K+T+YEFFL PF+ Sbjct: 693 LHISSTEEYIEGLYVRYRDLGANSQKYSMLTI-PNNAAEMHVITNLDKFTRYEFFLTPFF 751 Query: 712 KKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVV 771 K EG+PSNS+V QT +D P P+NI+ +LN T +KWSPP + QNG++ GY + V Sbjct: 752 KNVEGQPSNSKVVQTAEDAPTAAPVNIQTGMLNLTAGWVKWSPPPAEHQNGVLLGYKIQV 811 Query: 772 NWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDS 831 + + + +N+T TS+++ NLT+G +Y QI A +G GP+S+ Y +D Sbjct: 812 KAGNSSKTLASMTLNST---TTSVMLNNLTTGATYRAQIVAFNRVGAGPYSKPAYLIMDP 868 Query: 832 RSVGLDLLSRYPMNGEVSIVAGDFVMETWF--YFLIGAIVLFKIIVIAGIIYVRKYNIFA 889 V + ++ +F+ ETWF + ++ +++ V+ +++++K + Sbjct: 869 AHVIAPPRAHNSLSDIGGYRHHNFMHETWFMVFVVLALLIILTFTVVGVVVFIKKRQNMS 928 Query: 890 K 890 K Sbjct: 929 K 929 Score = 72.5 bits (170), Expect = 6e-11 Identities = 63/242 (26%), Positives = 104/242 (42%), Gaps = 17/242 (7%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG---VLVVSDTHRSI-LPAGGL 66 +P I +P D + AT C A G+P P++ W K G ++ ++T+ +I + + G Sbjct: 340 SPTFIIKPQDQRTNLNGVATFKCTASGNPPPSVFWTKEGSQTLMFPNNTYGNIHISSQGS 399 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-----FRLEPESKQSAQ 121 +R G D G + C A + G+ SR A L V + + P + + Sbjct: 400 LQVR---GAQKEDDGYFVCSALSVAGSTTSR-AYLQVTSSFDSSPPPVLQEVPSNLTLPR 455 Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181 G +L C G P +YWKKN + G R +V GG L I D + D+G Y C+ Sbjct: 456 GSIAMLPC-RGSGPTSPKIYWKKNATDITALG-PRFSIVQGGTLKIDDIQPEDSGWYSCV 513 Query: 182 ARNAAG-TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 A + G T SA ++ ++ L + S+ + + ++W + G Sbjct: 514 AYSEKGETSWSAFLQVEKNLSTMLPRSGSPELLPVAPSIPKAVNITNSNV-TLMWTKIGG 572 Query: 241 GG 242 GG Sbjct: 573 GG 574 Score = 35.9 bits (79), Expect = 6.7 Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 3/85 (3%) Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67 S P + E P ++T+ R A L CR G SP I W K + + R + GG Sbjct: 438 SSPPPVLQEVPSNLTLPRGSIAMLPCRGSGPTSPKIYWKKNATDITALGPRFSIVQGGTL 497 Query: 68 FLRATHGRVHSDAGVYWCEATNSYG 92 + D+G Y C A + G Sbjct: 498 KIDDIQ---PEDSGWYSCVAYSEKG 519 >UniRef50_Q17BD5 Cluster: Roundabout; n=1; Aedes aegypti|Rep: Roundabout - Aedes aegypti (Yellowfever mosquito) Length = 1117 Score = 598 bits (1476), Expect = e-169 Identities = 346/918 (37%), Positives = 501/918 (54%), Gaps = 57/918 (6%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64 Y +P I E P DVTV + P TLNC+A G P P ++W+K G V D++ +LPAG Sbjct: 20 YTAQYRSPRITEHPSDVTVPKGDPVTLNCQAEGKPQPVVQWFKDGDPVKLDSNHVLLPAG 79 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124 LFFLR H + D GVYWC A+N GT SRNATL VAVLR++FR+EP++ + A G+T Sbjct: 80 SLFFLRTLHSKKEQDDGVYWCVASNKAGTVHSRNATLQVAVLRDDFRVEPKNTRVAAGET 139 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGD------SRMHLVDGGNLVIQDARQTDAGRY 178 +LEC PRG+PEP++ WKK+ L D +R+ +VD GNL+I D R DAGRY Sbjct: 140 ALLECGAPRGNPEPSISWKKDDVLLDLDDYRVSKDLARIRIVDSGNLLISDVRPGDAGRY 199 Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238 QC+A+N G+RES A L + +KPY I P DV G+ V FQC VGGDP P VLW S Sbjct: 200 QCVAQNMVGSRESTYAKLAVQVKPYFIAKPSDVTVLEGNRVQFQCAVGGDPFPQVLW--S 257 Query: 239 AGGGNMPLGRVKVL-DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297 G++P+GR ++L +D SL + N D G+Y CEA NSVG +S L V PPS + Sbjct: 258 KENGHIPVGRAEILEEDRSLVIRNATPDDRGQYICEAHNSVGQISGRANLAVNTPPSFTV 317 Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 P V VA F C A+G P P++FW+ EG++T++FP + + + G L Sbjct: 318 RPQDQRVVPNGVATFRCDASGNPPPSVFWTKEGSQTLMFP----NNTYGSLQISGQGALQ 373 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD-DDRPPPIITNGPSNQTLPIKSMAV 416 I + D VCSA++ AGS R L VTS D PP++ P+NQ+LP S + Sbjct: 374 IRGVQRED-EGYYVCSALSVAGSVTSRVYLQVTSSLDSITPPVLQLVPTNQSLPTGSSTI 432 Query: 417 FPCTAICT---------PEPIIAWYFEGEALIQNHRRNVTN--DGTLVLKDLDKSDSGTY 465 PC T + I W G L +T G+L + DL DSG Y Sbjct: 433 LPCRFPPTSTNGQSNSMDDGRITWERNGFELSPASSTRITQLPAGSLKIDDLQVQDSGWY 492 Query: 466 TCVA--SSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLS 523 CVA S WS L V+ + + R + LP P P N+T+++VTL+ Sbjct: 493 RCVARVGSTVASSAWSAYLTVEDNLPTSQQ--RVFNGDLLPSAPGSPKALNITNSNVTLA 550 Query: 524 W---SQN----NKIGSSSILGYQVEVFSRETLSGNNTP----RNSRGWVVIARRVHQTHY 572 W S N +K SSS L Y +E F + S N+ P + GW + R + Sbjct: 551 WPIRSTNAPSPDKSRSSS-LTYTIEQFCLDDTSTNSLPTAPSQPDGGWEIALRHLAGNTA 609 Query: 573 VVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV-TVGDDSNSLWEGTGVSNSTEYRNNIL 631 V L P +Y+F+VR EN++G S PS VS + T+ D + V E N+L Sbjct: 610 TVTGLRPDTSYLFVVRAENAYGCSVPSAVSVPIRTLSSD-----DRVTVPAEMESARNVL 664 Query: 632 TDHIVELIEATPIDSKTIKLMWEI---LNFYYLEGLFIYFRPLDNITIEYEMKTILHSND 688 + I+ELI+ P+ S +++L W + + ++EG ++ +R LD+ T Y M +I +N+ Sbjct: 665 SGKILELIDIIPLSSTSVRLEWLLHVSSSEQFVEGFYVRYRELDSPTQRYSMLSI-PNNE 723 Query: 689 VSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTV 748 + IT+L K+TKYEFF PF+K EG+PSN+R+ QT++D+P P NI+ +LN T Sbjct: 724 IEQHIITNLAKFTKYEFFFTPFFKNLEGQPSNARIVQTMEDLPSIAPGNIQTGMLNLTAG 783 Query: 749 HLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSV 808 ++WSPP NG++ GY + V +V + + +N T TS+++ NLT+G SYS+ Sbjct: 784 WVRWSPPPKDQLNGVLQGYKIQVKAGNVSKLLAQMTLNAT---TTSVMLNNLTTGSSYSI 840 Query: 809 QIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETWF--YFLIG 866 ++ A +GLGP+S+ V+ +D V + N +F+ ETWF + ++ Sbjct: 841 RVGAFNRVGLGPYSKPVHLTMDPSFVIVPQGVHNSYNDYEDFRHHNFLHETWFMIFVVLS 900 Query: 867 AIVLFKIIVIAGIIYVRK 884 V+ ++ G+I+ ++ Sbjct: 901 LFVILLFTIVGGVIFFKR 918 >UniRef50_UPI0000DB7FD0 Cluster: PREDICTED: similar to roundabout CG13521-PA, isoform A, partial; n=1; Apis mellifera|Rep: PREDICTED: similar to roundabout CG13521-PA, isoform A, partial - Apis mellifera Length = 1389 Score = 580 bits (1431), Expect = e-163 Identities = 319/802 (39%), Positives = 466/802 (58%), Gaps = 38/802 (4%) Query: 100 TLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL 159 TL V VLR+EFR EP++ + A G+T +LEC PPRG PEP ++WK+NG T+ + R+ L Sbjct: 3 TLFVTVLRDEFRAEPQNTRVAAGETALLECGPPRGHPEPTLHWKRNGHTIDLETTKRITL 62 Query: 160 VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSV 219 VDGGNL+I D RQTD G+YQC+A N G +ESA+ATL +H+KP+ ++ P + + Sbjct: 63 VDGGNLMISDVRQTDQGKYQCVAENMVGVKESAVATLTVHVKPFFLSTPANQTILADQTA 122 Query: 220 TFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279 F CRVGGDP P++LWRR+ G MP+GR +LDD SLR++ V D+G Y C+AEN VG Sbjct: 123 EFACRVGGDPPPEILWRRN--DGKMPIGRAHILDDKSLRIERVTSQDQGTYICDAENGVG 180 Query: 280 AVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGM 339 A+SAS LTV+ P + P V G+ F+C A G P+P++FW+ EG++ ++FPG Sbjct: 181 AISASATLTVHSRPVFSSFPKDEIVSVGSNVSFSCAARGAPKPSIFWTREGSQELMFPGN 240 Query: 340 S-RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398 + +Y T DG L I D + VCSA++ AG+S L VTS ++ PPP Sbjct: 241 EYQSRYKITD--DG--SLHIKGVLGKDEGH-YVCSAISQAGASTATVFLQVTSVEEVPPP 295 Query: 399 IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE--ALIQNHRRNVTNDGTLVLKD 456 +I GP+NQTLP KS PC P P I WY E E + +++ + ++GTL +K+ Sbjct: 296 VIEIGPTNQTLPPKSDISMPCRVFGRPTPKIRWYKEDELVRIGSDNKFTIASNGTLSIKN 355 Query: 457 LDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVT 516 L SDSG Y CVASS G W +L + SP N H DVS+LP P+KP N T Sbjct: 356 LQLSDSGIYKCVASSESGNTSWIASLTI-SP-GANYHSI-IPDVSALPENPSKPRIVNTT 412 Query: 517 DTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKS 576 ++VTL+WS ++ G+S I+ Y VE F+ P+ S W+V + Y V + Sbjct: 413 SSTVTLTWSPGHE-GASKIIDYTVEYFA-------TNPKTS--WIVAGTEITDDIYTVTN 462 Query: 577 LIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIV 636 L P +Y+F+VR N+ GLS P P SD V +N + R+ L I+ Sbjct: 463 LTPDTSYVFLVRARNNQGLSVPGPFSD---VARTTNLDQHAIPQTELIRARDR-LNSEIL 518 Query: 637 ELIEATPIDSKTIKLMWEILNFYYL-EGLFIYFRPLDNITIEYEMKTILHSNDVSGFEIT 695 L + P+ S ++K++W+IL L EGL+I +R + EY M T+L++ S + +T Sbjct: 519 YLKDVQPLSSTSVKIVWDILGAADLVEGLYIRYREVSE-KPEYRMVTVLNAGATS-YVLT 576 Query: 696 SLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPP 755 +L KYT+YEFFL+PF+K EG+PSN ++A TL+D+P G P N+ + ++N T+ ++WSPP Sbjct: 577 NLNKYTRYEFFLVPFFKTIEGRPSNVKLATTLEDIPSGAPENVHVGMINITSAFVRWSPP 636 Query: 756 ELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETI 815 QNG + GY + + +NK + ++ TS+I+ +LT+G Y+ ++A T Sbjct: 637 PKSTQNGQLLGYKIQIK--SNSSNKILGQMSLNA-STTSVIINSLTTGGLYTARVAGYTR 693 Query: 816 IGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETWFYFLIGAIVLFKIIV 875 +G GPFS N+D L++ P + S V ETWF L+ +VL I Sbjct: 694 VGQGPFSNPTILNMDPGQ-----LTQLPPRTDPSQRNASVVSETWFLILMITVVLTVIAA 748 Query: 876 IAGIIYVRKYNIFAKKSALPNI 897 + G +YVR+ +K+ N+ Sbjct: 749 LLGAVYVRRRQAMSKQLGHLNV 770 Score = 149 bits (362), Expect = 3e-34 Identities = 101/325 (31%), Positives = 141/325 (43%), Gaps = 21/325 (6%) Query: 17 QPLDVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHG 74 +P + VA + A L C G P P + W + G + + T R L GG + Sbjct: 16 EPQNTRVAAGETALLECGPPRGHPEPTLHWKRNGHTIDLETTKRITLVDGGNLMISDVR- 74 Query: 75 RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRG 134 +D G Y C A N G S ATL V V + F L + Q+ D G Sbjct: 75 --QTDQGKYQCVAENMVGVKESAVATLTVHV--KPFFLSTPANQTILADQTAEFACRVGG 130 Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194 P P + W++N + R H++D +L I+ D G Y C A N G SA A Sbjct: 131 DPPPEILWRRNDGKMPI---GRAHILDDKSLRIERVTSQDQGTYICDAENGVGA-ISASA 186 Query: 195 TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG-----GGNMPLGRV 249 TL +H +P + P+D + GS+V+F C G P P + W R GN R Sbjct: 187 TLTVHSRPVFSSFPKDEIVSVGSNVSFSCAARGAPKPSIFWTREGSQELMFPGNEYQSRY 246 Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV-----YDPPSINLSPNSVNV 304 K+ DDGSL + V+ DEG Y C A + GA +A+ +L V PP I + P + + Sbjct: 247 KITDDGSLHIKGVLGKDEGHYVCSAISQAGASTATVFLQVTSVEEVPPPVIEIGPTNQTL 306 Query: 305 ESGNVARFTCTATGRPEPTMFWSVE 329 + C GRP P + W E Sbjct: 307 PPKSDISMPCRVFGRPTPKIRWYKE 331 Score = 118 bits (284), Expect = 1e-24 Identities = 92/326 (28%), Positives = 142/326 (43%), Gaps = 19/326 (5%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAGGLFFLR 70 P+ + P + T+ Q A CR GG P P I W + G + + H IL L R Sbjct: 105 PFFLSTPANQTILADQTAEFACRVGGDPPPEILWRRNDGKMPIGRAH--ILDDKSLRIER 162 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130 T D G Y C+A N G A S +ATL V R F P+ + + G V C Sbjct: 163 VT----SQDQGTYICDAENGVG-AISASATLTVH-SRPVFSSFPKDEIVSVGSNVSFSC- 215 Query: 131 PPRGSPEPNVYWKKNG-QTLLFDGD---SRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186 RG+P+P+++W + G Q L+F G+ SR + D G+L I+ D G Y C A + A Sbjct: 216 AARGAPKPSIFWTREGSQELMFPGNEYQSRYKITDDGSLHIKGVLGKDEGHYVCSAISQA 275 Query: 187 GTRESAIATLKIHIK----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242 G + + ++ P + GP + S ++ CRV G P P + W + Sbjct: 276 GASTATVFLQVTSVEEVPPPVIEIGPTNQTLPPKSDISMPCRVFGRPTPKIRWYKEDELV 335 Query: 243 NMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301 + + + +G+L + N+ L+D G Y C A + G S LT+ + + Sbjct: 336 RIGSDNKFTIASNGTLSIKNLQLSDSGIYKCVASSESGNTSWIASLTISPGANYHSIIPD 395 Query: 302 VNVESGNVARFTCTATGRPEPTMFWS 327 V+ N ++ T T+ WS Sbjct: 396 VSALPENPSKPRIVNTTSSTVTLTWS 421 Score = 57.2 bits (132), Expect = 3e-06 Identities = 48/202 (23%), Positives = 88/202 (43%), Gaps = 15/202 (7%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG---VLVVSDTHRS--I 60 +T P P D V+ + +C A G+P P+I W + G ++ + ++S Sbjct: 188 LTVHSRPVFSSFPKDEIVSVGSNVSFSCAARGAPKPSIFWTREGSQELMFPGNEYQSRYK 247 Query: 61 LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE----EFRLEPES 116 + G ++ G+ D G Y C A + G A + L V + E + P + Sbjct: 248 ITDDGSLHIKGVLGK---DEGHYVCSAISQAG-ASTATVFLQVTSVEEVPPPVIEIGPTN 303 Query: 117 KQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAG 176 + + + C G P P + W K + + D++ + G L I++ + +D+G Sbjct: 304 QTLPPKSDISMPC-RVFGRPTPKIRWYKEDELVRIGSDNKFTIASNGTLSIKNLQLSDSG 362 Query: 177 RYQCIARNAAGTRESAIATLKI 198 Y+C+A + +G S IA+L I Sbjct: 363 IYKCVASSESG-NTSWIASLTI 383 >UniRef50_Q98SW3 Cluster: Transmembrane receptor Roundabout3; n=23; Euteleostomi|Rep: Transmembrane receptor Roundabout3 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 1419 Score = 528 bits (1304), Expect = e-148 Identities = 308/829 (37%), Positives = 446/829 (53%), Gaps = 44/829 (5%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-----THRSILPAGG 65 AP I+E P D+ V++ +PATLNC+A G P+P + WYK G V +D +HR +LP+G Sbjct: 62 APRIVEHPSDLIVSKGEPATLNCKAEGRPTPMVEWYKDGERVETDREDPRSHRMLLPSGS 121 Query: 66 LFFLRATHGRVHS-DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124 LFFLR HGR D GVY C A N G A SRNA+L VA+LR++FR P A G+ Sbjct: 122 LFFLRIVHGRRSKPDEGVYVCVARNYLGEAVSRNASLEVAILRDDFRQTPSDVVVAAGEP 181 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 V+EC+PPRG PEP + WK+N + D D R+ + GG L+I + R++DAG Y C+ N Sbjct: 182 AVMECIPPRGHPEPTISWKRNN-VKVNDKDERI-TIRGGKLMISNTRKSDAGMYVCVGTN 239 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 G ++S A L + +P + P + V +V FQC V GDP P + W++ G + Sbjct: 240 MVGEKDSDPAELVVFERPMFVRRPVNQVVLADDTVDFQCEVQGDPAPTIRWKKEEG--EL 297 Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304 P GR ++ D SLRL V DEG Y+C +ENSVG ASG L V+ PP I + P Sbjct: 298 PRGRFEIRADNSLRLTQVKAEDEGSYTCLSENSVGKAEASGSLQVHVPPQIVVRPRDQIS 357 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV-FDGVTVLTINDTDK 363 G F C G P P +FW EG++ ++FP + +V G LTI D Sbjct: 358 AQGRTVTFLCGTKGNPPPAVFWQKEGSQVLLFPSQPPSQSGRFSVSLSG--ELTITDVHS 415 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTS-DDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422 DS +C A++ AGS + L V S DR PPII GP+NQTL + A C + Sbjct: 416 EDS-GYYICQAISVAGSILTKALLEVESTPSDRIPPIIRQGPANQTLAPGTTAQLQCHVM 474 Query: 423 CTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481 P P I W +G+ ++ + R ++ +GTL + L ++DSG YTCVASS G+ WSG Sbjct: 475 GNPLPSIQWERDGQRILGIDERISLMENGTLQITALQETDSGAYTCVASSLSGETSWSGV 534 Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541 L V + + ++ LPGPP KP+ +VT SVTL+W N G +++ Y +E Sbjct: 535 LTVKE--SGGLSASPVSEPYQLPGPPQKPVVTDVTRNSVTLTWQPNAHEGGAAVTSYIIE 592 Query: 542 VFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPV 601 FS+ S +T W +A V + V L P Y+FIVR N++GLS PSP+ Sbjct: 593 AFSQ---SAGST------WQTVADFVKLEKHTVTGLSPNTIYLFIVRAVNAYGLSDPSPI 643 Query: 602 SDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEI-LNFYY 660 S+ V D S + G GV + R L + V+L E + + ++K+ W + Y Sbjct: 644 SEPVRTQDVSPT---GQGVDHRQVQRE--LGEMSVQLHEPVLLTASSVKISWNVDRQSQY 698 Query: 661 LEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN 720 ++G + +RP+ + E+K + V I +L K T+YE + P++ +F+G S Sbjct: 699 IQGYRLLYRPVGGSWSQQEVKGATERSAV----IANLLKGTEYEIKIRPYFNEFQGLDSR 754 Query: 721 SRVAQTLDDVPDGPP--INIEMFIL-NTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVP 777 S+ +T ++VP PP +N+ L N++++ + W PP +QNG+I Y V W Sbjct: 755 SQTLRTPEEVPSAPPRAVNVATVKLSNSSSISVSWQPPPTDMQNGVIQEYKV---WCLGN 811 Query: 778 ANKSMVAINTTVH-QATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825 +++ IN TV S ++ L GV Y V++AA T G+G SQ V Sbjct: 812 DSQTRYNINQTVDGSVLSTVLKGLLPGVLYQVEVAAVTSAGVGKHSQPV 860 Score = 124 bits (300), Expect = 1e-26 Identities = 100/332 (30%), Positives = 147/332 (44%), Gaps = 26/332 (7%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P + +P++ V C G P+P IRW K + R L Sbjct: 255 ERPMFVRRPVNQVVLADDTVDFQCEVQGDPAPTIRWKK----EEGELPRGRFEIRADNSL 310 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 R T + D G Y C + NS G A + + +L V V + + P + SAQG TV C Sbjct: 311 RLTQVKA-EDEGSYTCLSENSVGKAEA-SGSLQVHV-PPQIVVRPRDQISAQGRTVTFLC 367 Query: 130 LPPRGSPEPNVYWKKNG-QTLLFDG-----DSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183 +G+P P V+W+K G Q LLF R + G L I D D+G Y C A Sbjct: 368 -GTKGNPPPAVFWQKEGSQVLLFPSQPPSQSGRFSVSLSGELTITDVHSEDSGYYICQAI 426 Query: 184 NAAGT-RESAI----ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238 + AG+ A+ +T I P + GP + G++ QC V G+PLP + W R Sbjct: 427 SVAGSILTKALLEVESTPSDRIPPIIRQGPANQTLAPGTTAQLQCHVMGNPLPSIQWERD 486 Query: 239 AGGGNMPLG---RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295 G LG R+ ++++G+L++ + D G Y+C A + G S SG LTV + + Sbjct: 487 ---GQRILGIDERISLMENGTLQITALQETDSGAYTCVASSLSGETSWSGVLTVKESGGL 543 Query: 296 NLSPNSVNVE-SGNVARFTCTATGRPEPTMFW 326 + SP S + G + T R T+ W Sbjct: 544 SASPVSEPYQLPGPPQKPVVTDVTRNSVTLTW 575 >UniRef50_Q9HCK4 Cluster: Roundabout homolog 2 precursor; n=45; Euteleostomi|Rep: Roundabout homolog 2 precursor - Homo sapiens (Human) Length = 1378 Score = 508 bits (1253), Expect = e-142 Identities = 300/827 (36%), Positives = 434/827 (52%), Gaps = 45/827 (5%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-----THRSILPAGGL 66 P I+E P DV V++ +P TLNC+A G P+P I WYK G V +D +HR +LP+G L Sbjct: 31 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSL 90 Query: 67 FFLRATHGRVHS-DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 FFLR HGR D G Y C A N G A SRNA+L VA+LR++FR P A G+ Sbjct: 91 FFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPA 150 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 +LEC PPRG PEP +YWKK+ + + D + R+ + GG L+I + R++DAG Y C+ N Sbjct: 151 ILECQPPRGHPEPTIYWKKD-KVRIDDKEERIS-IRGGKLMISNTRKSDAGMYTCVGTNM 208 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 G R+S A L + +P + P + V +V F+C+V GDP P V W++ ++P Sbjct: 209 VGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKD--DADLP 266 Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305 GR + DD +LR+ + DEG Y C AEN VG + AS LTV PP + P V Sbjct: 267 RGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVA 326 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365 G F C G P+P +FW EG++ ++FP + +V LTI + ++D Sbjct: 327 QGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSV-SPTGDLTITNIQRSD 385 Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSD-DDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424 + +C A+ AGS + +L VT DRPPPII GP+NQTL + A+ C A Sbjct: 386 A-GYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGD 444 Query: 425 PEPIIAWYFEGEALI-QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483 P P+I+W EG ++ R + GTL +K+L SD+GTYTCVA+S G+ WS L Sbjct: 445 PLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLD 504 Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543 V + D+S LPGPP+KP +VT SVTLSW Q G+ Y +E F Sbjct: 505 V---TESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSW-QPGTPGTLPASAYIIEAF 560 Query: 544 SRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603 S+ S W +A V T Y V+ L P Y+F+VR N GLS PSP+SD Sbjct: 561 SQSV---------SNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSD 611 Query: 604 SVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEI-LNFYYLE 662 V D S GV + + L D +V L + T+++ W + +++ Sbjct: 612 PVRTQDISP---PAQGVDHRQVQKE--LGDVLVRLHNPVVLTPTTVQVTWTVDRQPQFIQ 666 Query: 663 GLFIYFRPLDNI--TIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN 720 G + +R + T ++ + S + +L+K YE + P++ +F+G S Sbjct: 667 GYRVMYRQTSGLQATSSWQNLDAKVPTERSAV-LVNLKKGVTYEIKVRPYFNEFQGMDSE 725 Query: 721 SRVAQTLDDVPDGPPINIEMFIL---NTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVP 777 S+ +T ++ P PP ++ + + N+T++ + W PP QNGII Y + W Sbjct: 726 SKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKI---W--CL 780 Query: 778 ANKSMVAINTTVHQA-TSLIMTNLTSGVSYSVQIAAETIIGLGPFSQ 823 N++ IN TV A S+I+ L G+ Y V++AA T G+G S+ Sbjct: 781 GNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSE 827 Score = 120 bits (288), Expect = 3e-25 Identities = 85/295 (28%), Positives = 134/295 (45%), Gaps = 19/295 (6%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 +T E P + +P++ V + C+ G P P +RW K +D R Sbjct: 219 LTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDD----ADLPRGRYDIKD 274 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 + LR + +D G Y C A N G + +ATL V +F + P + AQG TV Sbjct: 275 DYTLRIKK-TMSTDEGTYMCIAENRVGKMEA-SATLTVRA-PPQFVVRPRDQIVAQGRTV 331 Query: 126 VLECLPPRGSPEPNVYWKKNG-QTLLFDG-----DSRMHLVDGGNLVIQDARQTDAGRYQ 179 C +G+P+P V+W+K G Q LLF +SR + G+L I + +++DAG Y Sbjct: 332 TFPC-ETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYI 390 Query: 180 CIARNAAGT-----RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL 234 C A AG+ + L P ++ GP + + +C+ GDPLP + Sbjct: 391 CQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVIS 450 Query: 235 WRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 W + R + + G+L++ N+ ++D G Y+C A +S G S S L V Sbjct: 451 WLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDV 505 Score = 61.7 bits (143), Expect = 1e-07 Identities = 49/190 (25%), Positives = 76/190 (40%), Gaps = 14/190 (7%) Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 PP I P+ V V G C A GRP PT+ W +G R + + H + Sbjct: 30 PPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGER--VETDKDDPRSHRMLLPS 87 Query: 352 G--VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG---KLTVTSDDDRPPPIITNGPSN 406 G + ++ + VC A NY G + R ++ + DD R P++ Sbjct: 88 GSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFR------QNPTD 141 Query: 407 QTLPIKSMAVFPC-TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465 + A+ C PEP I W + + R G L++ + KSD+G Y Sbjct: 142 VVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMY 201 Query: 466 TCVASSRHGK 475 TCV ++ G+ Sbjct: 202 TCVGTNMVGE 211 Score = 50.8 bits (116), Expect = 2e-04 Identities = 35/100 (35%), Positives = 48/100 (48%), Gaps = 4/100 (4%) Query: 4 DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63 D +T P I++ P + T+A A L C+A G P P I W K G R+ + Sbjct: 410 DVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQE 469 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103 G L+ + R+ SD G Y C AT+S G S +A L V Sbjct: 470 QGT--LQIKNLRI-SDTGTYTCVATSSSGET-SWSAVLDV 505 >UniRef50_O44928 Cluster: SAX-3; n=3; Caenorhabditis|Rep: SAX-3 - Caenorhabditis elegans Length = 1273 Score = 506 bits (1248), Expect = e-141 Identities = 333/1034 (32%), Positives = 510/1034 (49%), Gaps = 72/1034 (6%) Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSD-----THRSIL 61 S AP IIE P+DV V+R PATLNC G PS A I WYK G V+++ +HR +L Sbjct: 27 SNLAPVIIEHPIDVVVSRGSPATLNC--GAKPSTAKITWYKDGQPVITNKEQVNSHRIVL 84 Query: 62 PAGGLFFLRATHGR--VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS 119 G LF L+ G+ SDAG Y+C A+N +G +S +L +A+LRE+FR+ P + Q+ Sbjct: 85 DTGSLFLLKVNSGKNGKDSDAGAYYCVASNEHGEVKSNEGSLKLAMLREDFRVRPRTVQA 144 Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179 G+ VLEC PPRG PEP V W+K+ + L R L GNL+I ++D+G YQ Sbjct: 145 LGGEMAVLECSPPRGFPEPVVSWRKDDKELRIQDMPRYTLHSDGNLIIDPVDRSDSGTYQ 204 Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239 C+A N G R S A L + KP P+D+ G++V F CRV GDP P + W+R Sbjct: 205 CVANNMVGERVSNPARLSVFEKPKFEQEPKDMTVDVGAAVLFDCRVTGDPQPQITWKRK- 263 Query: 240 GGGNMPLGRVKVL-DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298 MP+ R + D+ LR++ V +DEGEY C A N G + AS +L V PPS Sbjct: 264 -NEPMPVTRAYIAKDNRGLRIERVQPSDEGEYVCYARNPAGTLEASAHLRVQAPPSFQTK 322 Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPG-MSRDKYHATAVFDGVTVLT 357 P +V +G A F CT G+P P FWS EG + ++FP +S D + +T+ Sbjct: 323 PADQSVPAGGTATFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGTLTIEE 382 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT------SDDDRPPPIITNGPSNQTLPI 411 + D+ VC+ +N AGSS + L VT + +PPP I +G NQTL + Sbjct: 383 VRQVDE----GAYVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQTLMV 438 Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470 S A+ PC A P P I+W +G + I + R + + G+L + DL K D+G YTC+A Sbjct: 439 GSSAILPCQASGKPTPGISWLRDGLPIDITDSRISQHSTGSLHIADLKKPDTGVYTCIAK 498 Query: 471 SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530 + G+ WS +L V+ + N F R D S+ P PT+PI NVTDT V L W+ + Sbjct: 499 NEDGESTWSASLTVEDHTS-NAQFVRMPDPSNFPSSPTQPIIVNVTDTEVELHWNAPSTS 557 Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590 G+ I GY ++ +S P + W I V T Y +K L P +YMF++R E Sbjct: 558 GAGPITGYIIQYYS---------PDLGQTWFNIPDYVASTEYRIKGLKPSHSYMFVIRAE 608 Query: 591 NSHGLSGPSPVSDSVTVGDDSNSL-WEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTI 649 N G+ PS S VT + + + + ++ +++L E I+S + Sbjct: 609 NEKGIGTPSVSSALVTTSKPAAQVALSDKNKMDMAIAEKRLTSEQLIKLEEVKTINSTAV 668 Query: 650 KLMWEILNFYYL-EGLFIYFR-PLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFL 707 +L W+ L +G +I +R P +Y T S + +++L +T YEFF+ Sbjct: 669 RLFWKKRKLEELIDGYYIKWRGPPRTNDNQYVNVT---SPSTENYVVSNLMPFTNYEFFV 725 Query: 708 IPFYK---KFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGII 764 IP++ G PSNS T + P PP ++ + +LN TT+ + W P+ NGI+ Sbjct: 726 IPYHSGVHSIHGAPSNSMDVLTAEAPPSLPPEDVRIRMLNLTTLRISWKAPKADGINGIL 785 Query: 765 TGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETI--IGLGPFS 822 G+ +V+ P N + TT +A S+ + +L +G++Y +++AA + +G+ + Sbjct: 786 KGFQIVIVG-QAPNNNRNI---TTNERAASVTLFHLVTGMTYKIRVAARSNGGVGVSHGT 841 Query: 823 QKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETWFYFLIGAIVLFKIIVIAGIIYV 882 +V N D+ L+ E + ++ +++F +I+IA + Sbjct: 842 SEVIMNQDT----LEKHLAAQQENESFLYGLINKSHVPVIVIVAILIIFVVIIIAYCYWR 897 Query: 883 RKYNIFAKKSALPNIYDSNGTSLVTQMNIKAAVSLSHPLTSCYNKNTVTKTESLLWMENQ 942 N K + I D G+ + N+ +P N+N + T + M N+ Sbjct: 898 NSRNSDGKDRSFIKIND--GSVHMASNNLWDVA--QNP-----NQNPMYNTAGRMTMNNR 948 Query: 943 PGVCL-SGNQTSQSKEKTNFEYDKVTHQLP-----EYAEVTSARANEWNT---NKTATSP 993 G L S +Q +Y H+ YA++T N +T N+ P Sbjct: 949 NGQALYSLTPNAQDFFNNCDDYSGTMHRPGSEHHYHYAQLTGGPGNAMSTFYGNQYHDDP 1008 Query: 994 AAYASVTLVANTRQ 1007 + YA+ TLV + +Q Sbjct: 1009 SPYATTTLVLSNQQ 1022 >UniRef50_Q9Y6N7 Cluster: Roundabout homolog 1 precursor; n=74; Coelomata|Rep: Roundabout homolog 1 precursor - Homo sapiens (Human) Length = 1651 Score = 500 bits (1232), Expect = e-139 Identities = 308/893 (34%), Positives = 458/893 (51%), Gaps = 64/893 (7%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-----THRSILPAGGL 66 P I+E P D+ V++ +PATLNC+A G P+P I WYKGG V +D +HR +LP+G L Sbjct: 68 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 127 Query: 67 FFLRATHGRV-HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 FFLR HGR D GVY C A N G A S NA+L VA+LR++FR P A G+ Sbjct: 128 FFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPA 187 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 V+EC PPRG PEP + WKK+G L D D R+ + GG L+I R++DAG+Y C+ N Sbjct: 188 VMECQPPRGHPEPTISWKKDGSPL-DDKDERI-TIRGGKLMITYTRKSDAGKYVCVGTNM 245 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 G RES +A L + +P + P ++ S F+C GDP+P V WR+ G +P Sbjct: 246 VGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKD--DGELP 303 Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305 R ++ DD +L++ V D G Y+C AEN VG AS LTV +PP + P V Sbjct: 304 KSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPRDQVVA 363 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIF---PGMSRDKYHATAVFDGVTVLTINDTD 362 G F C ATG P+P +FW EG++ ++F P S ++ + D LTI + Sbjct: 364 LGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGD----LTITNVQ 419 Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTS-DDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421 ++D +C +N AGS + L VT DRPPP+I GP NQT+ + V C A Sbjct: 420 RSDV-GYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVA 478 Query: 422 ICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480 +P P I W +G + Q+ R +G L ++ D+G YTC+AS+ G+ WS Sbjct: 479 TGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSA 538 Query: 481 ALLVDS---PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILG 537 + V P+ P R D + +P P+KP +V+ +VTLSW N G++ Sbjct: 539 YIEVQEFGVPVQPP----RPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATP-TS 593 Query: 538 YQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSG 597 Y +E FS SG++ W +A V +K L P Y+F+VR N++G+S Sbjct: 594 YIIEAFSH--ASGSS-------WQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISD 644 Query: 598 PSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEI-L 656 PS +SD V D L GV + R L + ++ L T + S +I++ W + Sbjct: 645 PSQISDPVKTQD---VLPTSQGVDHKQVQRE--LGNAVLHLHNPTVLSSSSIEVHWTVDQ 699 Query: 657 NFYYLEGLFIYFRPL-----DNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFY 711 Y++G I +RP ++ + +E++T ++ V I LRK YE PF+ Sbjct: 700 QSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKNSVV----IPDLRKGVNYEIKARPFF 755 Query: 712 KKFEGKPSNSRVAQTLDDVPDGPP--INIEMFILNTTTVHLKWSPPELQLQNGIITGYNV 769 +F+G S + A+TL++ P PP + + N T + + W PP QNG++ Y V Sbjct: 756 NEFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYKV 815 Query: 770 VVNWLDVPANKSMVAINTTVHQAT-SLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFN 828 W N++ IN TV +T S+++ L G+ YSV++AA T G G S+ + Sbjct: 816 ---W--CLGNETRYHINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSEPQFIQ 870 Query: 829 IDSRSVGLDLLSRYPMNGEVSIVAGDFVMETWFYFLIGAIVLFKIIVIAGIIY 881 +D+ + + + ++S D V + F IGA ++V + +Y Sbjct: 871 LDAHGNPVSPEDQVSLAQQIS----DVVKQPAFIAGIGAACWIILMVFSIWLY 919 Score = 115 bits (277), Expect = 7e-24 Identities = 98/333 (29%), Positives = 148/333 (44%), Gaps = 31/333 (9%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFF 68 E P +++P ++ V A C A G P P +RW K G L S I L Sbjct: 260 ERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS--RYEIRDDHTLKI 317 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128 + T G D G Y C A N G A + +ATL V F ++P + A G TV + Sbjct: 318 RKVTAG----DMGSYTCVAENMVGKAEA-SATLTVQE-PPHFVVKPRDQVVALGRTVTFQ 371 Query: 129 CLPPRGSPEPNVYWKKNG-QTLLF-----DGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182 C G+P+P ++W++ G Q LLF SR + G+L I + +++D G Y C Sbjct: 372 C-EATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQT 430 Query: 183 RNAAG---TRESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 N AG T+ T I + P + GP + + C G P+P +LWR+ Sbjct: 431 LNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRK 490 Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD------ 291 + R+K L++G L++ L D G Y+C A G + S Y+ V + Sbjct: 491 DGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQ 550 Query: 292 ---PPSINLSPNSVN-VESGNVARFTCTATGRP 320 P NL P++ + E +V+R T T + +P Sbjct: 551 PPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQP 583 Score = 79.4 bits (187), Expect = 6e-13 Identities = 62/195 (31%), Positives = 91/195 (46%), Gaps = 20/195 (10%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV--------SDTH 57 +T E P+ + +P D VA + T C A G+P PAI W + G + S + Sbjct: 345 LTVQEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSR 404 Query: 58 RSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA-VLREE----FRL 112 S+ G L SD G Y C+ N G+ ++ A L V V+ + R Sbjct: 405 FSVSQTGDLTITNVQ----RSDVGYYICQTLNVAGSIITK-AYLEVTDVIADRPPPVIRQ 459 Query: 113 EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ 172 P ++ A T VL C+ GSP P + W+K+G L+ DSR+ ++ G L I+ A+ Sbjct: 460 GPVNQTVAVDGTFVLSCV-ATGSPVPTILWRKDG-VLVSTQDSRIKQLENGVLQIRYAKL 517 Query: 173 TDAGRYQCIARNAAG 187 D GRY CIA +G Sbjct: 518 GDTGRYTCIASTPSG 532 Score = 64.5 bits (150), Expect = 2e-08 Identities = 51/190 (26%), Positives = 75/190 (39%), Gaps = 14/190 (7%) Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 PP I P+ + V G A C A GRP PT+ W G R + + H + Sbjct: 67 PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGER--VETDKDDPRSHRMLLPS 124 Query: 352 G--VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG---KLTVTSDDDRPPPIITNGPSN 406 G + ++ VC A NY G + ++ + DD R PS+ Sbjct: 125 GSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFR------QNPSD 178 Query: 407 QTLPIKSMAVFPC-TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465 + + AV C PEP I+W +G L R G L++ KSD+G Y Sbjct: 179 VMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKY 238 Query: 466 TCVASSRHGK 475 CV ++ G+ Sbjct: 239 VCVGTNMVGE 248 Score = 46.0 bits (104), Expect = 0.006 Identities = 31/91 (34%), Positives = 43/91 (47%), Gaps = 3/91 (3%) Query: 4 DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63 D + P I + P++ TVA L+C A GSP P I W K GVLV + R Sbjct: 447 DVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLE 506 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTA 94 G+ +R + ++ D G Y C A+ G A Sbjct: 507 NGVLQIR--YAKL-GDTGRYTCIASTPSGEA 534 >UniRef50_Q4RRT1 Cluster: Chromosome 16 SCAF15002, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 16 SCAF15002, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1098 Score = 444 bits (1094), Expect = e-123 Identities = 259/650 (39%), Positives = 345/650 (53%), Gaps = 30/650 (4%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-----THRSILPAGGL 66 P I E P D+ V++ +PATLNC+A G P+P I WYK G V +D +HR +LP+G L Sbjct: 17 PRIAEDPSDLIVSKGEPATLNCKAEGRPTPIIEWYKDGERVETDRDDPRSHRMLLPSGSL 76 Query: 67 FFLRATHGRVHS-DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 FFLR HGR D GVY C A N G A SRNA+L VA+LR++FR P A G+ Sbjct: 77 FFLRIVHGRRSKPDEGVYTCVARNYLGEAVSRNASLDVAILRDDFRQAPSDVVVAAGEPA 136 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 VLEC+PPRG PEP V+WK+N + D R+ + GG L+I AR++DAG Y C+ +N Sbjct: 137 VLECVPPRGHPEPIVFWKRNN-VRIGSKDDRIAM-RGGKLMISHARKSDAGMYVCVGKNM 194 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 G R+S A L ++ +P L+ P + V +V FQC V GDP P V WRR G +P Sbjct: 195 VGERDSDPAELVVYERPVLVRRPVNQVVMEEDTVDFQCEVHGDPAPTVRWRREEG--ELP 252 Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305 GR ++ + LRL +V DEG Y+C +ENSVG AS L V+ PP I P Sbjct: 253 RGRFEIHNGNILRLFHVKEEDEGMYTCTSENSVGKTEASAMLQVHVPPQIATKPRDQIAT 312 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365 G F C TG P P +FW EG++ ++FPG + +V LTI D D Sbjct: 313 QGRSVTFECGTTGNPPPAIFWQKEGSQMLLFPGQPPSQSGRYSVSMSGD-LTITDVHPED 371 Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVT-SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424 S +C A++ AGS + L V +R PPII GP+NQT + + C I Sbjct: 372 S-GFYICQAISVAGSVMSKVLLDVEGGPSNRIPPIIRQGPANQTATLGATVQLHCRVIGG 430 Query: 425 PEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483 P I+W GE L N R + +GTL + D+ ++DSGTYTC+ASS G+ WSG L Sbjct: 431 PSIHISWEKNGEELHGNEARLTLMENGTLQITDIKETDSGTYTCIASSATGESSWSGTLT 490 Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543 V R ++ LPGPP KP+ VT +VTL+W N G +++ Y +E F Sbjct: 491 VRE--YGVYSTSRISEFIQLPGPPQKPVMTEVTKNTVTLTWQSNPHEGGAAVTSYIIEAF 548 Query: 544 SRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603 S+ S W +A V Q + V L P Y+FIVR NS+GLS PSP+S+ Sbjct: 549 SQSVGS---------TWQTVADHVKQERHTVVGLFPNTVYLFIVRAVNSYGLSDPSPISE 599 Query: 604 SVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMW 653 V D S + G GV + R L D V L + + + L W Sbjct: 600 PVRTQDGSPT---GEGVDHRQVQRE--LGDVSVYLQKPVILSPTSASLSW 644 Score = 118 bits (284), Expect = 1e-24 Identities = 83/291 (28%), Positives = 133/291 (45%), Gaps = 19/291 (6%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P ++ +P++ V C G P+P +RW + + R L Sbjct: 209 ERPVLVRRPVNQVVMEEDTVDFQCEVHGDPAPTVRWRR----EEGELPRGRFEIHNGNIL 264 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 R H + D G+Y C + NS G + +A L V V + +P + + QG +V EC Sbjct: 265 RLFHVK-EEDEGMYTCTSENSVGKTEA-SAMLQVHV-PPQIATKPRDQIATQGRSVTFEC 321 Query: 130 LPPRGSPEPNVYWKKNG-QTLLFDG-----DSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183 G+P P ++W+K G Q LLF G R + G+L I D D+G Y C A Sbjct: 322 -GTTGNPPPAIFWQKEGSQMLLFPGQPPSQSGRYSVSMSGDLTITDVHPEDSGFYICQAI 380 Query: 184 NAAGTRESAI-----ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238 + AG+ S + I P + GP + A G++V CRV G P + W ++ Sbjct: 381 SVAGSVMSKVLLDVEGGPSNRIPPIIRQGPANQTATLGATVQLHCRVIGGPSIHISWEKN 440 Query: 239 AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 + R+ ++++G+L++ ++ D G Y+C A ++ G S SG LTV Sbjct: 441 GEELHGNEARLTLMENGTLQITDIKETDSGTYTCIASSATGESSWSGTLTV 491 Score = 58.4 bits (135), Expect = 1e-06 Identities = 51/201 (25%), Positives = 76/201 (37%), Gaps = 16/201 (7%) Query: 283 ASGYLTVYD--PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340 +SG T ++ PP I P+ + V G A C A GRP P + W +G R + Sbjct: 5 SSGSRTRFEDSPPRIAEDPSDLIVSKGEPATLNCKAEGRPTPIIEWYKDGER--VETDRD 62 Query: 341 RDKYHATAVFDG--VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG---KLTVTSDDDR 395 + H + G + ++ C A NY G + R + + DD R Sbjct: 63 DPRSHRMLLPSGSLFFLRIVHGRRSKPDEGVYTCVARNYLGEAVSRNASLDVAILRDDFR 122 Query: 396 PPPIITNGPSNQTLPIKSMAVFPCT-AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVL 454 PS+ + AV C PEPI+ W + R G L++ Sbjct: 123 ------QAPSDVVVAAGEPAVLECVPPRGHPEPIVFWKRNNVRIGSKDDRIAMRGGKLMI 176 Query: 455 KDLDKSDSGTYTCVASSRHGK 475 KSD+G Y CV + G+ Sbjct: 177 SHARKSDAGMYVCVGKNMVGE 197 >UniRef50_Q96MS0 Cluster: Roundabout homolog 3 precursor; n=23; Euteleostomi|Rep: Roundabout homolog 3 precursor - Homo sapiens (Human) Length = 1386 Score = 436 bits (1073), Expect = e-120 Identities = 283/834 (33%), Positives = 414/834 (49%), Gaps = 45/834 (5%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-----DTHRSILPAGGL 66 P I+EQP D+ V+R +PATL CRA G P P I WYK G V + HR +LP+G L Sbjct: 64 PRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGAL 123 Query: 67 FFLRATHGR-VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 FF R HGR D GVY C A N G A SRNA+L VAVLR++FR P + A G+ Sbjct: 124 FFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPA 183 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 VLEC+PPRG PEP+V W+K+G L + + R+ + GG L++ ++DAG Y C+A N Sbjct: 184 VLECVPPRGHPEPSVSWRKDGARLK-EEEGRI-TIRGGKLMMSHTLKSDAGMYVCVASNM 241 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 AG RESA A + + +P + P + V + VTF C V GDP P + WR+ G +P Sbjct: 242 AGERESAAAEVMVLERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKE--DGELP 299 Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305 GR ++ D SL + +V DEG Y+C AENSVG ASG L+V+ PP + P Sbjct: 300 TGRYEIRSDHSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQDQMAA 359 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365 G F C G P P +FW EG++ ++FP S +V L I + D Sbjct: 360 PGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSV-SPRGQLNITAVQRGD 418 Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDD-DRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424 + VC AV+ AGS + L + D PP+I GP+NQTL + S PC Sbjct: 419 A-GYYVCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGN 477 Query: 425 PEPIIAWYFEGEALIQNHRRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483 P+P + W +G+ L + + T +GTL + ++ + D G Y+CVA S G+ WSG L Sbjct: 478 PQPSVRWKKDGQWLQGDDLQFKTMANGTLYIANVQEMDMGFYSCVAKSSTGEATWSGWLK 537 Query: 484 V--DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541 + D ++P+ + SS PG P++P+ +T S+TL+W N + G +++ Y +E Sbjct: 538 MREDWGVSPD----PPTEPSSPPGAPSQPVVTEITKNSITLTWKPNPQTG-AAVTSYVIE 592 Query: 542 VFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPV 601 FS P W +A V + V L P Y+F+VR + GLS PSPV Sbjct: 593 AFS---------PAAGNTWRTVADGVQLETHTVSGLQPNTIYLFLVRAVGAWGLSEPSPV 643 Query: 602 SDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILN-FYY 660 S+ V D S S V + + L + V L E + +T+++ W + Sbjct: 644 SEPVRTQDSSPS----RPVEDPWRGQQG-LAEVAVRLQEPIVLGPRTLQVSWTVDGPVQL 698 Query: 661 LEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN 720 ++G + +R + M L S + L T+ + + ++ G S Sbjct: 699 VQGFRVSWRVAGPEGGSWTMLD-LQSPSQQSTVLRGLPPGTQIQIKVQAQGQEGLGAESL 757 Query: 721 SRVAQTLDDVPDGPPINIEMFI--LNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPA 778 S ++ P GPP + + + +++ + W PP QNG+IT Y + W Sbjct: 758 SVTRSIPEEAPSGPPQGVAVALGGDGNSSITVSWEPPLPSQQNGVITEYQI---W--CLG 812 Query: 779 NKSMVAIN-TTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDS 831 N+S +N + A S ++ L G+ Y +AA T G+G S V + S Sbjct: 813 NESRFHLNRSAAGWARSAMLRGLVPGLLYRTLVAAATSAGVGVPSAPVLVQLPS 866 Score = 126 bits (303), Expect = 5e-27 Identities = 102/339 (30%), Positives = 157/339 (46%), Gaps = 40/339 (11%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P + +P++ V P T C G P P +RW K LP G + + Sbjct: 256 ERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRK---------EDGELPT-GRYEI 305 Query: 70 RATH----GRVHS-DAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESKQSAQGD 123 R+ H G V + D G Y C A NS G A S + ++HV + +P+ + +A G+ Sbjct: 306 RSDHSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVP---PQLVTQPQDQMAAPGE 362 Query: 124 TVVLECLPPRGSPEPNVYWKKNG-QTLLFDGDS-----RMHLVDGGNLVIQDARQTDAGR 177 +V +C +G+P P ++W+K G Q LLF S R + G L I ++ DAG Sbjct: 363 SVAFQC-ETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGY 421 Query: 178 YQCIARNAAGT-RESAIATLK----IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232 Y C A + AG+ A+ +K + P ++ GP + GSSV CRV G+P P Sbjct: 422 YVCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPS 481 Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-- 290 V W++ + K + +G+L + NV D G YSC A++S G + SG+L + Sbjct: 482 VRWKKDGQWLQGDDLQFKTMANGTLYIANVQEMDMGFYSCVAKSSTGEATWSGWLKMRED 541 Query: 291 -----DPPSINLSPNSVNVES--GNVARFTCTATGRPEP 322 DPP+ SP + + + + T T +P P Sbjct: 542 WGVSPDPPTEPSSPPGAPSQPVVTEITKNSITLTWKPNP 580 Score = 45.2 bits (102), Expect = 0.011 Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 3/86 (3%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68 G P I++ P + T+ L CR G+P P++RW K G + D + A G + Sbjct: 448 GLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTMANGTLY 507 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTA 94 + D G Y C A +S G A Sbjct: 508 IANVQ---EMDMGFYSCVAKSSTGEA 530 >UniRef50_UPI0000E4900E Cluster: PREDICTED: similar to transmembrane receptor Roundabout3; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to transmembrane receptor Roundabout3 - Strongylocentrotus purpuratus Length = 1613 Score = 429 bits (1057), Expect = e-118 Identities = 290/859 (33%), Positives = 426/859 (49%), Gaps = 49/859 (5%) Query: 38 SPSPAIRWYKGG--VLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTAR 95 +P + W K G + + D H + L G LFFLR RV D GVY C ATNS G A Sbjct: 175 APRFQVNWLKDGQPLEMKGDGHLTALSTGALFFLRVIP-RV--DIGVYQCVATNSLGVAY 231 Query: 96 SRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155 S+NA+L +A LR +FR EP + G+ VVLEC PPRG PEP V W++NGQT++ DG Sbjct: 232 SKNASLDIAYLRGDFRQEPSDTMALLGEAVVLECSPPRGHPEPEVSWERNGQTVVEDG-I 290 Query: 156 RMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT 215 R+ ++ GNLVI + +D G Y C+A N+ G + SA L I+ +P P D +A Sbjct: 291 RVRILTDGNLVISQPKSSDIGNYVCVATNSEGAKRSAAGRLIINSRPAFTEVPFDTLAIP 350 Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAE 275 G ++T C G+P P + W + G +PL R +L D SLR+ N +D G Y C A+ Sbjct: 351 GETITLPCVAEGEPAPTIRWVKQ--DGTLPLNRNTMLQDSSLRISNAESSDSGTYICTAQ 408 Query: 276 NSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII 335 N+ G S +TV P P V G A F C ATG P P+++W G + ++ Sbjct: 409 NTWGDKSVEAIVTVSSAPMFTRVPVDRTVVVGQDAFFLCQATGLPTPSIYWKERGAKPLM 468 Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395 FPG ++ T DG L + T +N+ VCSA++ GS L V D+ Sbjct: 469 FPGDRNAQFEVTN--DGRLHL-FSVTRENE--GYYVCSAMSGRGSVEDSAYLRVLDDNLP 523 Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVL 454 PPII GPSNQTL S A C A +P I W +G L + R + GTL Sbjct: 524 LPPIIHIGPSNQTLVEGSPAQLICQAEGRSQPSIDWLKDGAPLQLVGTRITLDGSGTLKF 583 Query: 455 KDLDKSDSGTYTCVASSRHGKYVWSGAL-LVDSPINPNIHFFRAADVSSLPGPPTKPITH 513 L D+G+YTC A++ G WS +L ++ A V+ LP P PI Sbjct: 584 SSLTPDDAGSYTCSAANSVGATKWSSSLQVIRRAFAGTEQVHEAPSVTQLPQAPGFPIVD 643 Query: 514 NVTDTSVTLSWSQNNKI--GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTH 571 N+T T++ L+W + + S+ GY+VE F TP GW V A R+ Sbjct: 644 NITRTTMRLTWPSARPLPDRTVSLTGYRVEYF---------TPDRITGWTVAAVRIQGNS 694 Query: 572 YVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEG----TGVSN-STE- 625 + V++L PG TY+F+VR N+HG PSPVS + ++ G GV+ +TE Sbjct: 695 FEVRNLEPGFTYVFMVRGINAHGYGPPSPVSIAANTPTGTHREVPGPNAEPGVTTPATEG 754 Query: 626 -YRNNILTDHI----VELIEATPIDSKTIKLMWEIL-NFYYLEGLFIYFRPLDNITIEYE 679 +IL D + V + + ++ I + W+I+ N Y++G ++ P +E Sbjct: 755 AESRDILQDKLDNCGVYIKRVQVLGTQAINVTWQIIRNGDYIDGYYLKVTPQVKAPGIFE 814 Query: 680 MKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKF-EGKPSNSRVAQTLDDVPDGPPINI 738 M ++ ND + + L+ +T+Y + P++ + G+ S V +T DVP PP +I Sbjct: 815 MNRVV--NDKTAVQ-GGLQPWTEYAITIQPYHGAWHRGRESRKVVIKTAQDVPRAPPNSI 871 Query: 739 EMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMT 798 + +T++ + W PP + GII GY++ + P + + I T ++ + + Sbjct: 872 KARQNGSTSIKVSWRPPAVNQVPGIIAGYHIFCLSENPPHHPN---ITTRNNRTLEVAVP 928 Query: 799 NLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAG-DFVM 857 NL G Y V++AA TI G+GPFS VY + G D + N + G D + Sbjct: 929 NLRPGAQYGVKVAAYTIAGMGPFSDIVYVTLPP---GPDDPEKRGSNDGLDSGGGMDILS 985 Query: 858 ETWFYFLIGAIVLFKIIVI 876 E WFY + +LF I I Sbjct: 986 EPWFYAAVALALLFVITSI 1004 Score = 203 bits (495), Expect = 3e-50 Identities = 167/527 (31%), Positives = 249/527 (47%), Gaps = 46/527 (8%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG--VLVVSDTHRSILPAGGLFFL 69 P I E P ++ ++ PATLNCRA G P+P + W K G + + D H + L G LFFL Sbjct: 65 PRITEHPSGQSIRKNSPATLNCRAEGFPAPDLHWLKDGQPLEMKGDGHLTALSTGALFFL 124 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 R RV D GVY C ATNS G A S+NA+L +A ++ + ++ V+ C Sbjct: 125 RVI-PRV--DIGVYQCVATNSLGVAYSKNASLDIASFVMDWGI-------TSFESGVMAC 174 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNL-VIQDARQTDAGRYQCIARNAAGT 188 +P V W K+GQ L GD + + G L ++ + D G YQC+A N+ G Sbjct: 175 -----APRFQVNWLKDGQPLEMKGDGHLTALSTGALFFLRVIPRVDIGVYQCVATNSLGV 229 Query: 189 RESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVLWRRSAGGGNMPL 246 S A+L I +++ P D +A G +V +C G P P+V W R+ Sbjct: 230 AYSKNASLDIAYLRGDFRQEPSDTMALLGEAVVLECSPPRGHPEPEVSWERNGQTVVEDG 289 Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV-SASGYLTVYDPPSINLSPNSVNVE 305 RV++L DG+L + +D G Y C A NS GA SA+G L + P+ P Sbjct: 290 IRVRILTDGNLVISQPKSSDIGNYVCVATNSEGAKRSAAGRLIINSRPAFTEVPFDTLAI 349 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365 G C A G P PT+ W V+ + T+ ++R+ T + D + L I++ + +D Sbjct: 350 PGETITLPCVAEGEPAPTIRW-VKQDGTL---PLNRN----TMLQD--SSLRISNAESSD 399 Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425 S T +C+A N G V +TV+S P+ T P ++T+ + A F C A P Sbjct: 400 S-GTYICTAQNTWGDKSVEAIVTVSS-----APMFTRVPVDRTVVVGQDAFFLCQATGLP 453 Query: 426 EPIIAWYFEGEALI-----QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480 P I W G + +N + VTNDG L L + + + G Y C A S G S Sbjct: 454 TPSIYWKERGAKPLMFPGDRNAQFEVTNDGRLHLFSVTRENEGYYVCSAMSGRGSVEDSA 513 Query: 481 ALLV---DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSW 524 L V + P+ P IH ++ + + G P + I + ++ W Sbjct: 514 YLRVLDDNLPLPPIIH-IGPSNQTLVEGSPAQLICQAEGRSQPSIDW 559 Score = 62.5 bits (145), Expect = 7e-08 Identities = 65/240 (27%), Positives = 100/240 (41%), Gaps = 21/240 (8%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG---VLVVSDTHR--SI 60 VT AP P+D TV Q A C+A G P+P+I W + G ++ D + + Sbjct: 420 VTVSSAPMFTRVPVDRTVVVGQDAFFLCQATGLPTPSIYWKERGAKPLMFPGDRNAQFEV 479 Query: 61 LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV----AVLREEFRLEPES 116 G L T + G Y C A + G+ +A L V L + P + Sbjct: 480 TNDGRLHLFSVT----RENEGYYVCSAMSGRGSVED-SAYLRVLDDNLPLPPIIHIGPSN 534 Query: 117 KQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAG 176 + +G L C G +P++ W K+G L G +R+ L G L DAG Sbjct: 535 QTLVEGSPAQLIC-QAEGRSQPSIDWLKDGAPLQLVG-TRITLDGSGTLKFSSLTPDDAG 592 Query: 177 RYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 Y C A N+ G + + ++L++ + + G E V SVT + G P+ D + R Sbjct: 593 SYTCSAANSVGATKWS-SSLQVIRRAF--AGTEQV--HEAPSVTQLPQAPGFPIVDNITR 647 Score = 43.2 bits (97), Expect = 0.044 Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 3/85 (3%) Query: 393 DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI---QNHRRNVTND 449 ++ PP IT PS Q++ S A C A P P + W +G+ L H ++ Sbjct: 60 NEESPPRITEHPSGQSIRKNSPATLNCRAEGFPAPDLHWLKDGQPLEMKGDGHLTALSTG 119 Query: 450 GTLVLKDLDKSDSGTYTCVASSRHG 474 L+ + + D G Y CVA++ G Sbjct: 120 ALFFLRVIPRVDIGVYQCVATNSLG 144 >UniRef50_UPI0000E46659 Cluster: PREDICTED: similar to roundabout homolog 2; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to roundabout homolog 2 - Strongylocentrotus purpuratus Length = 1809 Score = 412 bits (1014), Expect = e-113 Identities = 239/655 (36%), Positives = 338/655 (51%), Gaps = 30/655 (4%) Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGG 65 T AP I EQP + V R PA+ NC+A G P P I W K G LV+ DT ++L +G Sbjct: 17 TEESAPTITEQPKSLIVTRGDPASFNCKAEGRPEPTISWLKNGQPLVIRDTRHTVLDSGS 76 Query: 66 LFFLRATHGRVHS-DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124 LFFL+ R D GVY C A NS GTA S NATL +A LRE+FR EP S Q GD+ Sbjct: 77 LFFLQVVGNRQGGQDGGVYQCMAHNSLGTAYSANATLEIAYLREDFREEPVSDQLISGDS 136 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 VLEC PPRG P P V W K+ Q ++ D ++R+ +V+ GNL++++ R+ D G Y+C A+N Sbjct: 137 AVLECTPPRGYPTPEVTWLKDDQPIILD-NNRVKIVEDGNLLLKELRKDDEGTYKCKAQN 195 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 AG R S A L + +KP I P+D + G + +C V GDP P V W R G + Sbjct: 196 VAGERISKDAYLTVQVKPAFINPPQDTITAPGEAAVLRCEVEGDPPPTVSWSREI--GEL 253 Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304 P GR + L D SLR+ + D+G Y C AEN G A L V P +P V Sbjct: 254 PDGRTQQLPDNSLRIRHTDELDDGVYICTAENIWGTSDAKARLRVSAVPDFIRAPRDKTV 313 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNR-TIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363 + RF C A G P P++ W G ++F R ++ +A + L IN Sbjct: 314 HVNEMVRFQCEAVGSPPPSIHWQKAGTEDNLLFINQQRGRFEVSASGE----LQINPVQM 369 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423 +D+ T +C A G + + L V + PPP+I GP+NQTL + S A F C + Sbjct: 370 DDA-GTYICYATGGTGVAEAKAVLRVLDESLAPPPLIQYGPANQTLVVGSTATFMCRSAG 428 Query: 424 TPEPIIAWYFEGEALIQNHRR--NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481 P P I W +G AL ++ R + D TL + + DSG Y+C+ASS G+ S Sbjct: 429 NPSPQIEWTKDGIALTTSNPRFSLMYPDNTLEITGVQVDDSGLYSCLASSNSGETSQSAT 488 Query: 482 LLV-DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQV 540 LLV +S I A ++ LPG P++P+ NVT +S+ + W+ + S+ GYQV Sbjct: 489 LLVIESTETSGIPVKTAPSINELPGSPSQPLRVNVTRSSIQVRWTAPAANRAPSVTGYQV 548 Query: 541 EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600 E FS P GWVV + Y + L+P +++ +VR NS+G+ P P Sbjct: 549 EYFS---------PERVTGWVVAGNGIQGETYNINHLVPSSSHLVVVRAINSNGIGPPGP 599 Query: 601 VSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEI 655 +S+S++ + E S E ++ + VE+ + S IK+ WE+ Sbjct: 600 MSESISTSE------ETANPPPSRECLSD-QSSITVEITTIIALSSTAIKVSWEV 647 Score = 116 bits (279), Expect = 4e-24 Identities = 106/355 (29%), Positives = 148/355 (41%), Gaps = 37/355 (10%) Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62 D Y+T P I P D A + A L C G P P + W + + + D LP Sbjct: 204 DAYLTVQVKPAFINPPQDTITAPGEAAVLRCEVEGDPPPTVSWSR-EIGELPDGRTQQLP 262 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122 LR H D GVY C A N +GT+ ++ A L V+ + +F P K Sbjct: 263 DNS---LRIRH-TDELDDGVYICTAENIWGTSDAK-ARLRVSAV-PDFIRAPRDKTVHVN 316 Query: 123 DTVVLECLPPRGSPEPNVYWKKNG--QTLLFDGD--SRMHLVDGGNLVIQDARQTDAGRY 178 + V +C GSP P+++W+K G LLF R + G L I + DAG Y Sbjct: 317 EMVRFQC-EAVGSPPPSIHWQKAGTEDNLLFINQQRGRFEVSASGELQINPVQMDDAGTY 375 Query: 179 QCIARNAAGTRESAIATLKIHIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233 C A G E A A L++ + P + GP + GS+ TF CR G+P P + Sbjct: 376 ICYATGGTGVAE-AKAVLRVLDESLAPPPLIQYGPANQTLVVGSTATFMCRSAGNPSPQI 434 Query: 234 LWRRSAGGGNMPLGRVKVL-DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD- 291 W + R ++ D +L + V + D G YSC A ++ G S S L V + Sbjct: 435 EWTKDGIALTTSNPRFSLMYPDNTLEITGVQVDDSGLYSCLASSNSGETSQSATLLVIES 494 Query: 292 ----------PPSINLSPNS------VNVESGNV-ARFTCTATGRPEPTMFWSVE 329 PSIN P S VNV ++ R+T A R + VE Sbjct: 495 TETSGIPVKTAPSINELPGSPSQPLRVNVTRSSIQVRWTAPAANRAPSVTGYQVE 549 Score = 87.8 bits (208), Expect = 2e-15 Identities = 90/375 (24%), Positives = 146/375 (38%), Gaps = 32/375 (8%) Query: 515 VTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVV 574 ++ T++ +SW + I GYQV + S + V ++ Sbjct: 636 LSSTAIKVSWEVHTPANEDQIDGYQVRYLLSDGASRTH----------FQTVVGMLSTIL 685 Query: 575 KSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDH 634 L P + Y VR + + SP + T+ + S L V N L Sbjct: 686 TGLDPSMDYTVSVRPQICNSKGQESPSVAARTMSEGSGPLC----VHGDNRILQNKLDGS 741 Query: 635 IVELIEATPIDSKTIKLMWEILNF--YYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGF 692 V ++ + S +++ WEI Y+EG I +R + + Y ++TI + F Sbjct: 742 DVHIVGTETVGSNALQVKWEIARHAAAYVEGFHIKYRTSSSSSSNYSVETI--TGPARTF 799 Query: 693 EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKW 752 + L + +Y + PF + G+ T D P GPP N+ T+ V ++W Sbjct: 800 VLNGLTSWQEYSISVQPFSGLYCGQEGEQIKTWTAADRPRGPPRNVIARSNGTSAVLVQW 859 Query: 753 SPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLI--MTNLTSGVSYSVQI 810 P L G I GY ++ N S A N T+ T+ I + L +G Y VQ+ Sbjct: 860 HAPGRDLVQGYIEGY-----YISCRGNISSHARNRTIQGNTTFIGRVGGLQAGKVYWVQV 914 Query: 811 AAETIIGLGPFSQKVYFNIDSR-SVGLDLLSRYPMNGEVSIVAGDFVMETWFYFLIGAIV 869 AA T G GP S V + S + L P N + G+ + W Y +I IV Sbjct: 915 AAFTAAGAGPSSPVVLVTVASPIPIDAGLADSDPEN-----IDGE-ATKPWVYAIIATIV 968 Query: 870 LFKIIVIAGIIYVRK 884 +V+ + R+ Sbjct: 969 FIIALVLIAFVLRRR 983 Score = 79.0 bits (186), Expect = 7e-13 Identities = 70/248 (28%), Positives = 102/248 (41%), Gaps = 19/248 (7%) Query: 285 GYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344 G T P+I P S+ V G+ A F C A GRPEPT+ W G +I RD Sbjct: 14 GRRTEESAPTITEQPKSLIVTRGDPASFNCKAEGRPEPTISWLKNGQPLVI-----RDTR 68 Query: 345 HATAVFDGVTVL-TINDTDKNDSRNTIVCSAVNYAGSSFVRG---KLTVTSDDDRPPPII 400 H + L + + C A N G+++ ++ +D R P+ Sbjct: 69 HTVLDSGSLFFLQVVGNRQGGQDGGVYQCMAHNSLGTAYSANATLEIAYLREDFREEPV- 127 Query: 401 TNGPSNQTLPIKSMAVFPCT-AICTPEPIIAWYFEGEALI-QNHRRNVTNDGTLVLKDLD 458 S+Q + S AV CT P P + W + + +I N+R + DG L+LK+L Sbjct: 128 ----SDQLISGDS-AVLECTPPRGYPTPEVTWLKDDQPIILDNNRVKIVEDGNLLLKELR 182 Query: 459 KSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDT 518 K D GTY C A + G+ + A L + P D + PG D Sbjct: 183 KDDEGTYKCKAQNVAGERISKDAYLT-VQVKP-AFINPPQDTITAPGEAAVLRCEVEGDP 240 Query: 519 SVTLSWSQ 526 T+SWS+ Sbjct: 241 PPTVSWSR 248 >UniRef50_UPI0000ECA411 Cluster: UPI0000ECA411 related cluster; n=1; Gallus gallus|Rep: UPI0000ECA411 UniRef100 entry - Gallus gallus Length = 1213 Score = 341 bits (838), Expect = 7e-92 Identities = 192/464 (41%), Positives = 257/464 (55%), Gaps = 20/464 (4%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD----THRSILPAGGL 66 AP I+E P D+ V+R +PATL+CRA G PSP + WYK G V +D +HR +LP+G L Sbjct: 10 APRIVEHPSDLLVSRGEPATLSCRAEGRPSPTVEWYKDGERVETDKDPRSHRMLLPSGSL 69 Query: 67 FFLRATHGRVHS-DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 FF R HGR D G+Y C A N YG A SRNA+L VAVLR++FR P A G+ Sbjct: 70 FF-RIVHGRRSKPDEGIYVCVARN-YGEATSRNASLEVAVLRDDFRQSPGDVVVAAGEPA 127 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 VLEC+PPRG PEP V WKK+G T L D D R+ + GG L++ R++DAG Y C+A N Sbjct: 128 VLECVPPRGHPEPTVTWKKDG-TRLSDKDERI-TIRGGKLMMATTRKSDAGIYVCVATNM 185 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 G R+S A L + +P P++ + F C GDPLP WRR G +P Sbjct: 186 VGERDSEPAELVVFERPAFGRRPQNQAVLEDQAAEFPCEALGDPLPTARWRRE--DGELP 243 Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305 GR ++L D +LR+ V DEG Y+C AENSVG ASG L V PP + P + V Sbjct: 244 AGRWELLADNTLRISRVRAEDEGTYTCMAENSVGRSEASGTLIVRVPPQLITRPRNQTVS 303 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD--GVTVLTINDTDK 363 G F C TG P P +FW EG++T++FPG S +V +T+ T+ TD Sbjct: 304 PGQTVTFQCETTGNPPPAVFWQKEGSQTLLFPGQSPPPASRISVASSGAMTIATVQPTD- 362 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP-PPIITNGPSNQT-LPIKSMAVFPCTA 421 +C A++ AGS + L V + P PP+I GP+N T LP+ + PC A Sbjct: 363 ---AGYYLCQAISVAGSILAKALLEVEAAPAEPRPPLIRWGPANLTVLPVGATVQLPCWA 419 Query: 422 ICTPEPIIAWYFEGEALIQNH-RRNVTNDGTLVLKDLDKSDSGT 464 P P + W +G + + R ++ +GTL + L S +GT Sbjct: 420 EGEPPPRVGWLKDGRTVPGSEGRASLLENGTLQISSLRVSCTGT 463 Score = 116 bits (279), Expect = 4e-24 Identities = 113/411 (27%), Positives = 163/411 (39%), Gaps = 39/411 (9%) Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH--LVDGGNL---VIQ 168 P ++G+ L C G P P V W K+G+ + D D R H L+ G+L ++ Sbjct: 17 PSDLLVSRGEPATLSCRA-EGRPSPTVEWYKDGERVETDKDPRSHRMLLPSGSLFFRIVH 75 Query: 169 DAR-QTDAGRYQCIARNAAGTRESAIATLKIHI-KPYLITGPEDVVAQTGSSVTFQC-RV 225 R + D G Y C+ARN G S A+L++ + + P DVV G +C Sbjct: 76 GRRSKPDEGIYVCVARNY-GEATSRNASLEVAVLRDDFRQSPGDVVVAAGEPAVLECVPP 134 Query: 226 GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV-SAS 284 G P P V W++ + R+ + G L + +D G Y C A N VG S Sbjct: 135 RGHPEPTVTWKKDGTRLSDKDERITIRG-GKLMMATTRKSDAGIYVCVATNMVGERDSEP 193 Query: 285 GYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344 L V++ P+ P + V A F C A G P PT W E + ++ Sbjct: 194 AELVVFERPAFGRRPQNQAVLEDQAAEFPCEALGDPLPTARWRREDGE------LPAGRW 247 Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404 A L I+ D T C A N G S G L V R PP + P Sbjct: 248 ELLAD----NTLRISRVRAEDE-GTYTCMAENSVGRSEASGTLIV-----RVPPQLITRP 297 Query: 405 SNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI--------QNHRRNVTNDGTLVLKD 456 NQT+ F C P P + W EG + R +V + G + + Sbjct: 298 RNQTVSPGQTVTFQCETTGNPPPAVFWQKEGSQTLLFPGQSPPPASRISVASSGAMTIAT 357 Query: 457 LDKSDSGTYTCVASSRHGKYVWSGALLVD-SPINPNIHFFR--AADVSSLP 504 + +D+G Y C A S G + L V+ +P P R A+++ LP Sbjct: 358 VQPTDAGYYLCQAISVAGSILAKALLEVEAAPAEPRPPLIRWGPANLTVLP 408 Score = 95.5 bits (227), Expect = 8e-18 Identities = 87/273 (31%), Positives = 127/273 (46%), Gaps = 24/273 (8%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFF 68 E P +P + V Q A C A G P P RW + G L R L A Sbjct: 200 ERPAFGRRPQNQAVLEDQAAEFPCEALGDPLPTARWRREDGELPAG---RWELLADNT-- 254 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128 LR + R D G Y C A NS G + + + TL V V + P ++ + G TV + Sbjct: 255 LRISRVRA-EDEGTYTCMAENSVGRSEA-SGTLIVRV-PPQLITRPRNQTVSPGQTVTFQ 311 Query: 129 CLPPRGSPEPNVYWKKNG-QTLLFDGD-----SRMHLVDGGNLVIQDARQTDAGRYQCIA 182 C G+P P V+W+K G QTLLF G SR+ + G + I + TDAG Y C A Sbjct: 312 C-ETTGNPPPAVFWQKEGSQTLLFPGQSPPPASRISVASSGAMTIATVQPTDAGYYLCQA 370 Query: 183 RNAAGTRESAIATLKIHI-----KPYLIT-GPEDV-VAQTGSSVTFQCRVGGDPLPDVLW 235 + AG+ A A L++ +P LI GP ++ V G++V C G+P P V W Sbjct: 371 ISVAGS-ILAKALLEVEAAPAEPRPPLIRWGPANLTVLPVGATVQLPCWAEGEPPPRVGW 429 Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268 + GR +L++G+L++ ++ ++ G Sbjct: 430 LKDGRTVPGSEGRASLLENGTLQISSLRVSCTG 462 Score = 91.5 bits (217), Expect = 1e-16 Identities = 87/295 (29%), Positives = 112/295 (37%), Gaps = 24/295 (8%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM---PLGRVKVLDDGSLR 258 P ++ P D++ G T CR G P P V W + P +L GSL Sbjct: 11 PRIVEHPSDLLVSRGEPATLSCRAEGRPSPTVEWYKDGERVETDKDPRSHRMLLPSGSLF 70 Query: 259 LDNV----ILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLSPNSVNVESGNVARFT 313 V DEG Y C A N A S + L V SP V V +G A Sbjct: 71 FRIVHGRRSKPDEGIYVCVARNYGEATSRNASLEVAVLRDDFRQSPGDVVVAAGEPAVLE 130 Query: 314 CTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372 C G PEPT+ W +G R DK + G ++ T K+D+ VC Sbjct: 131 CVPPRGHPEPTVTWKKDGTRL-------SDKDERITIRGGKLMMAT--TRKSDA-GIYVC 180 Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432 A N G V + P P NQ + A FPC A+ P P W Sbjct: 181 VATNMVGERDSEPAELVVFER----PAFGRRPQNQAVLEDQAAEFPCEALGDPLPTARWR 236 Query: 433 FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 E L R + D TL + + D GTYTC+A + G+ SG L+V P Sbjct: 237 REDGELPAG-RWELLADNTLRISRVRAEDEGTYTCMAENSVGRSEASGTLIVRVP 290 Score = 63.7 bits (148), Expect = 3e-08 Identities = 43/140 (30%), Positives = 63/140 (45%), Gaps = 7/140 (5%) Query: 691 GFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHL 750 G +T LR+ YE + PFY G S R + + P PP + + N T+V + Sbjct: 599 GALLTGLRRGQDYEVKVRPFYLHLHGPDSAVRALRMPEAAPSAPPRAVSV-AGNGTSVRI 657 Query: 751 KWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH-QATSLIMTNLTSGVSYSVQ 809 W PP QNG+I Y + W N+S IN +V + ++ L GV Y + Sbjct: 658 SWQPPPPAEQNGVILDYRI---W--CLGNESRFHINQSVEGTVLATVLRGLVPGVPYRAE 712 Query: 810 IAAETIIGLGPFSQKVYFNI 829 +AA T G+G S + I Sbjct: 713 VAAATGAGVGARSAPISIRI 732 >UniRef50_A1XCJ3 Cluster: RoboA; n=1; Schmidtea mediterranea|Rep: RoboA - Schmidtea mediterranea (Freshwater planarian flatworm) Length = 1402 Score = 281 bits (689), Expect = 8e-74 Identities = 189/608 (31%), Positives = 276/608 (45%), Gaps = 32/608 (5%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-----DTHRSILPAG 64 + P I E P Q +L C A G P P I WYK G +V S T ++ Sbjct: 24 QKPIISEHPASTHGLSLQRVSLRCSAKGDPMPNIIWYKDGQVVESYRDKPATSNRLVKDN 83 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124 L F+ D GVY+C A+N +G S NA++ +A L ++ + PESK ++ G+T Sbjct: 84 ELLFMHLDT----QDEGVYYCNASNIHGWTISNNASVLIAFLNKDI-IGPESKTASVGET 138 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 V++EC PP+G P+P V WK NG + + + R+ ++D GNL I A + D+GRY C+A+N Sbjct: 139 VLMECKPPKGVPKPTVIWKFNGNAI--EVNKRIKILDNGNLRIDKATRKDSGRYNCLAKN 196 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 A R+S A L + KP P ++ + + F C GDP P ++WRR + Sbjct: 197 FADERDSTSALLTVRQKPQFKIAPSNIEVKVNEAAVFPCVADGDPKPTIVWRRD-NQKKI 255 Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304 P R ++D+ +++ V L D G Y C A NS G + A L+V P +P++ V Sbjct: 256 PSSRATLIDNKGMQISKVQLTDMGNYICHASNSAGHLEAYAKLSVVSTPGFIETPDNQKV 315 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 G+ A F C TG P+PT+ WS G+ I SR D + LTIN + Sbjct: 316 RVGDTAIFNCRVTGSPQPTIIWSHNGDHFIADEENSRRSERIQV--DKLGSLTINPVKIS 373 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424 DS C A +Y G L V PP+I GP NQTL I A F C Sbjct: 374 DS-GKYECKASSYIGKIQSSASLHVIDAQKYVPPVIEVGPQNQTLRIGLTATFNCQPKQQ 432 Query: 425 PEPIIAWYFEGEA--LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482 + + W G L+ + R G L + L SD+G YTC +WS L Sbjct: 433 DDVTVHWLKNGHQLNLVSDPRIITLTTGKLKINLLRMSDAGNYTCKIVQNEAFTLWSVTL 492 Query: 483 -LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541 ++D D LP PT D+ +T W +N ++I Y +E Sbjct: 493 KILDKNDYETAIMQTIDDARMLPSAPTNFEVIERGDSWITFKW-ENPPQEETNINHYLIE 551 Query: 542 VFSRETLSGNNTPRNSR-GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600 +P SR GW + + + + +L P Y F++R+ N G+ P+ Sbjct: 552 Y----------SPYESRQGW-YMQSIILSSPGKITNLHPNTGYRFLIRSVNDIGIGNPNV 600 Query: 601 VSDSVTVG 608 +S V G Sbjct: 601 ISFVVFTG 608 Score = 95.1 bits (226), Expect = 1e-17 Identities = 68/278 (24%), Positives = 128/278 (46%), Gaps = 17/278 (6%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 +T + P P ++ V ++ A C A G P P I W + + + +++ G Sbjct: 208 LTVRQKPQFKIAPSNIEVKVNEAAVFPCVADGDPKPTIVWRRDNQKKIPSSRATLIDNKG 267 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 + + +D G Y C A+NS G + A L V V F P++++ GDT Sbjct: 268 MQISKVQ----LTDMGNYICHASNSAGHLEA-YAKLSV-VSTPGFIETPDNQKVRVGDTA 321 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDS-----RMHLVDGGNLVIQDARQTDAGRYQC 180 + C GSP+P + W NG + D ++ R+ + G+L I + +D+G+Y+C Sbjct: 322 IFNC-RVTGSPQPTIIWSHNGDHFIADEENSRRSERIQVDKLGSLTINPVKISDSGKYEC 380 Query: 181 IARNAAGTRESA----IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 A + G +S+ + + ++ P + GP++ + G + TF C+ V W Sbjct: 381 KASSYIGKIQSSASLHVIDAQKYVPPVIEVGPQNQTLRIGLTATFNCQPKQQDDVTVHWL 440 Query: 237 RSAGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCE 273 ++ N+ R+ L G L+++ + ++D G Y+C+ Sbjct: 441 KNGHQLNLVSDPRIITLTTGKLKINLLRMSDAGNYTCK 478 Score = 60.5 bits (140), Expect = 3e-07 Identities = 64/253 (25%), Positives = 110/253 (43%), Gaps = 27/253 (10%) Query: 694 ITSLRKYTKYEFFLIPF-----YKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTV 748 I+ L + Y+ ++ P+ + K G S + T D VP P ++ L+ T+V Sbjct: 733 ISKLEPFVCYDVYVQPYLDNNKFGKLTGTVSKAITILTYDSVPTKSPTDLTARWLSNTSV 792 Query: 749 HLKWSPPELQLQNGIITGYNVVVNWLDVPANKSM-VAINTTVHQATSLIMTNLTSGVSYS 807 + W P ++ NGI+ GY++ + D + +S+ V+ +TV + L++ + Y Sbjct: 793 EISWKPAPMRHINGILKGYSLHIIGNDTNSTRSIEVSPKSTVVRVQDLLI-----NMPYI 847 Query: 808 VQIAAETIIGLGPFSQKVYFNIDSRSVGLD---LLSRYPMNGEVSIVAGDFVMETWF--Y 862 V IAA T G G S + S + + L R N I+A + WF Sbjct: 848 VHIAASTCQGEGICSAGLMLTASSSLITMSPNYLERRLGQNFAKPIIA-SVTKQPWFISI 906 Query: 863 FLIGAIVLFKIIVIAGIIYVRKYNIFAKKSALPNIYDSNGTSLVTQMNIKAAVS------ 916 ++G + F +I I V +++ + + Y SNGT L++ N + V Sbjct: 907 MVVGGCLWF---MICAFILVVCRSMYLRGLIYKSGY-SNGTKLISNSNSQLPVGSSNGRL 962 Query: 917 LSHPLTSCYNKNT 929 SH + S N NT Sbjct: 963 TSHQIVSHMNTNT 975 >UniRef50_UPI0000EBE6C5 Cluster: PREDICTED: hypothetical protein; n=3; Bos taurus|Rep: PREDICTED: hypothetical protein - Bos taurus Length = 349 Score = 280 bits (687), Expect = 1e-73 Identities = 145/327 (44%), Positives = 189/327 (57%), Gaps = 10/327 (3%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-----THRSILPAGGL 66 P I+EQP D+ V+R +PATL CRA G P P I WYK G V + HR +LP+G L Sbjct: 20 PRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATAREDPRAHRLLLPSGAL 79 Query: 67 FFLRATHGR-VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 FF R HGR D GVY C A N G A SRNA+L VAVLR++FR P + A G+ Sbjct: 80 FFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPA 139 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 V+EC+PPRG PEP+V WKK+G L + + R+ + GG L++ ++DAG Y C+A N Sbjct: 140 VMECMPPRGHPEPSVSWKKDG-VRLKEEEGRI-TIRGGKLMMSHTFKSDAGMYVCVASNM 197 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 AG RES A L + +P + P + V G+ V F C V GDP P + WR+ G +P Sbjct: 198 AGERESGAAKLVVLERPSFLRRPVNQVVLAGAPVDFPCEVQGDPPPRLRWRKE--DGELP 255 Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305 GR ++ D SL++ V DEG Y+C AENSVG ASG L V+ PP + P Sbjct: 256 TGRYEIQSDHSLQIGRVSAEDEGTYTCVAENSVGRAEASGSLIVHVPPQLVTQPQDQMAA 315 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNR 332 G+ F C G P P +FW EG++ Sbjct: 316 PGDSVAFQCETKGNPPPAIFWQKEGSQ 342 Score = 116 bits (278), Expect = 5e-24 Identities = 74/230 (32%), Positives = 107/230 (46%), Gaps = 11/230 (4%) Query: 16 EQPLDVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74 + P +V VA +PA + C G P P++ W K GV + + R + G L +H Sbjct: 126 QSPGNVVVAVGEPAVMECMPPRGHPEPSVSWKKDGVRLKEEEGRITIRGGKLMM---SH- 181 Query: 75 RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRG 134 SDAG+Y C A+N G S A L V + R F P ++ G V C +G Sbjct: 182 TFKSDAGMYVCVASNMAGERESGAAKL-VVLERPSFLRRPVNQVVLAGAPVDFPC-EVQG 239 Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194 P P + W+K L R + +L I D G Y C+A N+ G R A Sbjct: 240 DPPPRLRWRKEDGEL---PTGRYEIQSDHSLQIGRVSAEDEGTYTCVAENSVG-RAEASG 295 Query: 195 TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 +L +H+ P L+T P+D +A G SV FQC G+P P + W++ N+ Sbjct: 296 SLIVHVPPQLVTQPQDQMAAPGDSVAFQCETKGNPPPAIFWQKEGSQANL 345 Score = 90.6 bits (215), Expect = 2e-16 Identities = 86/299 (28%), Positives = 126/299 (42%), Gaps = 29/299 (9%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGGGNMPLGRVKVLDDGSL 257 P ++ P D++ G T CR G P P++ W R A P +L G+L Sbjct: 20 PRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATAREDPRAHRLLLPSGAL 79 Query: 258 RLDNVILA-----DEGEYSCEAENSVGAV-SASGYLTVYD-PPSINLSPNSVNVESGNVA 310 ++ DEG Y+C A N +GA S + L V SP +V V G A Sbjct: 80 FFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPA 139 Query: 311 RFTCTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369 C G PEP++ W +G R +++ + G L ++ T K+D+ Sbjct: 140 VMECMPPRGHPEPSVSWKKDGVRL-------KEEEGRITIRGGK--LMMSHTFKSDA-GM 189 Query: 370 IVCSAVNYAGS-SFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428 VC A N AG KL V +RP P NQ + + FPC P P Sbjct: 190 YVCVASNMAGERESGAAKLVVL---ERPS--FLRRPVNQVVLAGAPVDFPCEVQGDPPPR 244 Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 + W E + + R + +D +L + + D GTYTCVA + G+ SG+L+V P Sbjct: 245 LRWRKE-DGELPTGRYEIQSDHSLQIGRVSAEDEGTYTCVAENSVGRAEASGSLIVHVP 302 Score = 62.9 bits (146), Expect = 5e-08 Identities = 43/143 (30%), Positives = 67/143 (46%), Gaps = 20/143 (13%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P + +P++ V P C G P P +RW K LP G + + Sbjct: 212 ERPSFLRRPVNQVVLAGAPVDFPCEVQGDPPPRLRWRK---------EDGELPT-GRYEI 261 Query: 70 RATH----GRVHS-DAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESKQSAQGD 123 ++ H GRV + D G Y C A NS G A S + +HV + +P+ + +A GD Sbjct: 262 QSDHSLQIGRVSAEDEGTYTCVAENSVGRAEASGSLIVHVP---PQLVTQPQDQMAAPGD 318 Query: 124 TVVLECLPPRGSPEPNVYWKKNG 146 +V +C +G+P P ++W+K G Sbjct: 319 SVAFQC-ETKGNPPPAIFWQKEG 340 >UniRef50_Q172F7 Cluster: Roundabout, putative; n=2; Culicidae|Rep: Roundabout, putative - Aedes aegypti (Yellowfever mosquito) Length = 1086 Score = 268 bits (657), Expect = 6e-70 Identities = 131/315 (41%), Positives = 179/315 (56%), Gaps = 3/315 (0%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I E P D A+ +P TLNC+A G P P I WY GV + R +LP G LFFL+ Sbjct: 16 PRIQEHPADAVAAKEEPLTLNCKAVGRPPPDINWYHNGVPLGPSDRRVVLPEGSLFFLKV 75 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131 + DAGVY CEA NS G A SRNATL +A+L++EFR P+ + G V+L C P Sbjct: 76 MQNKREQDAGVYHCEAHNSAGVAVSRNATLQIAMLKDEFRAMPKDTVALVGGPVILNCTP 135 Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191 PRG PEP+V W K+G+ L G R+ +VD G+L+I + + D G+Y+C A++ AGT+ + Sbjct: 136 PRGIPEPSVLWIKDGKLLDISG-KRLSMVDSGSLMISEIQPNDTGKYECSAQSMAGTKTT 194 Query: 192 AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251 A LK+ P ++ P D G C + GDP P V WR+ + G +P GR + Sbjct: 195 PPAYLKVLAPPTIVKSPHDTEVLEGEGFDLPCELAGDPKPVVTWRKES--GRLPEGRSRK 252 Query: 252 LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVAR 311 L D +LR+++ DEG+Y CE N G V+ S YL VY+ P+ +P V + G Sbjct: 253 LLDNTLRIEDARQDDEGKYICEGHNEGGNVTISVYLYVYEAPTFMEAPVDVVIREGEGIT 312 Query: 312 FTCTATGRPEPTMFW 326 C A GRP +FW Sbjct: 313 LPCRAKGRPGVRIFW 327 Score = 115 bits (277), Expect = 7e-24 Identities = 99/335 (29%), Positives = 138/335 (41%), Gaps = 24/335 (7%) Query: 103 VAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG 162 VA LR + P +A+ + + L C G P P++ W NG L D R+ L +G Sbjct: 11 VAQLRPRIQEHPADAVAAKEEPLTLNCKAV-GRPPPDINWYHNGVPL-GPSDRRVVLPEG 68 Query: 163 GNL---VIQDARQTDAGRYQCIARNAAGTRESAIATLKIH-IKPYLITGPEDVVAQTGSS 218 V+Q+ R+ DAG Y C A N+AG S ATL+I +K P+D VA G Sbjct: 69 SLFFLKVMQNKREQDAGVYHCEAHNSAGVAVSRNATLQIAMLKDEFRAMPKDTVALVGGP 128 Query: 219 VTFQCRVG-GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENS 277 V C G P P VLW + ++ R+ ++D GSL + + D G+Y C A++ Sbjct: 129 VILNCTPPRGIPEPSVLWIKDGKLLDISGKRLSMVDSGSLMISEIQPNDTGKYECSAQSM 188 Query: 278 VGA-VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF 336 G + YL V PP+I SP+ V G C G P+P + W E R + Sbjct: 189 AGTKTTPPAYLKVLAPPTIVKSPHDTEVLEGEGFDLPCELAGDPKPVVTWRKESGR--LP 246 Query: 337 PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP 396 G SR T L I D + D +C N G+ + L V Sbjct: 247 EGRSRKLLDNT--------LRIEDA-RQDDEGKYICEGHNEGGNVTISVYLYVYE----- 292 Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431 P P + + PC A P I W Sbjct: 293 APTFMEAPVDVVIREGEGITLPCRAKGRPGVRIFW 327 Score = 103 bits (247), Expect = 3e-20 Identities = 67/281 (23%), Positives = 136/281 (48%), Gaps = 21/281 (7%) Query: 631 LTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFR----PLDNITIEYEMKTILHS 686 +++ + L I + +I + W++ + L +Y+R P+DN ++ + + Sbjct: 497 VSEQFIVLNNVFTISASSIGISWDVTDSATKMPLRMYYRVASEPMDNFIYNSTFESQVTT 556 Query: 687 NDVSGFEITSLRKYTKYEFFL-IPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNT 745 +++ + LR +T+YE F IP + G SN R +TLD P PP ++ + ++NT Sbjct: 557 SNLKELTLNDLRPFTEYEIFASIP--EGLSGSVSNIRRGKTLDGPPSAPPTDVRVGVINT 614 Query: 746 TTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVS 805 T ++WSPP + + NG +TGY + + + +N+T S+++ +LT G Sbjct: 615 TAAFVRWSPPPVHMLNGELTGYKIQIKSNATNKVLGQMILNSTTQ---SVVINSLTPGAM 671 Query: 806 YSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETWFYFLI 865 Y ++A+ T G+GP+S ++D +++ RYP + M +W Sbjct: 672 YIAKVASLTSGGIGPYSLPTSLHMDPQNI-----VRYPKTDPTP----SYWMSSWMSGT- 721 Query: 866 GAIVLFKIIVIAGIIYVRKYNIFAKKSALPNIYDSNGTSLV 906 A+V+ + +I G I+ + + K+S + + T+++ Sbjct: 722 -ALVILCVCLIGGAIFAIFWTVRKKQSVKASYPGPSVTTII 761 Score = 88.6 bits (210), Expect = 9e-16 Identities = 69/222 (31%), Positives = 97/222 (43%), Gaps = 12/222 (5%) Query: 18 PLDVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGR 75 P D P LNC G P P++ W K G L+ +S S++ +G L Sbjct: 118 PKDTVALVGGPVILNCTPPRGIPEPSVLWIKDGKLLDISGKRLSMVDSGSLMISEIQP-- 175 Query: 76 VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGS 135 +D G Y C A + GT + A L V + P + +G+ L C G Sbjct: 176 --NDTGKYECSAQSMAGTKTTPPAYLKVLAPPTIVK-SPHDTEVLEGEGFDLPC-ELAGD 231 Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195 P+P V W+K L +G SR L+D L I+DARQ D G+Y C N G ++ Sbjct: 232 PKPVVTWRKESGRLP-EGRSRK-LLDN-TLRIEDARQDDEGKYICEGHNEGGNVTISVY- 287 Query: 196 LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 L ++ P + P DVV + G +T CR G P + W R Sbjct: 288 LYVYEAPTFMEAPVDVVIREGEGITLPCRAKGRPGVRIFWDR 329 Score = 81.8 bits (193), Expect = 1e-13 Identities = 80/305 (26%), Positives = 126/305 (41%), Gaps = 31/305 (10%) Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLR- 258 ++P + P D VA +T C+ G P PD+ W + G P R VL +GSL Sbjct: 14 LRPRIQEHPADAVAAKEEPLTLNCKAVGRPPPDINWYHN-GVPLGPSDRRVVLPEGSLFF 72 Query: 259 ---LDNVILADEGEYSCEAENSVG-AVSASGYLTVYD-PPSINLSPNSVNVESGNVARFT 313 + N D G Y CEA NS G AVS + L + P G Sbjct: 73 LKVMQNKREQDAGVYHCEAHNSAGVAVSRNATLQIAMLKDEFRAMPKDTVALVGGPVILN 132 Query: 314 CTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372 CT G PEP++ W +G + + G + ++ ++ + NDT K + C Sbjct: 133 CTPPRGIPEPSVLWIKDG-KLLDISGKRLSMVDSGSLM--ISEIQPNDTGKYE------C 183 Query: 373 SAVNYAGSSFVR-GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431 SA + AG+ L V + PP I+ + + L + + PC P+P++ W Sbjct: 184 SAQSMAGTKTTPPAYLKVLA----PPTIVKSPHDTEVLEGEGFDL-PCELAGDPKPVVTW 238 Query: 432 YFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK-------YVWSGALLV 484 E L + R + D TL ++D + D G Y C + G YV+ + Sbjct: 239 RKESGRLPEGRSRKLL-DNTLRIEDARQDDEGKYICEGHNEGGNVTISVYLYVYEAPTFM 297 Query: 485 DSPIN 489 ++P++ Sbjct: 298 EAPVD 302 Score = 41.1 bits (92), Expect = 0.18 Identities = 30/113 (26%), Positives = 47/113 (41%), Gaps = 4/113 (3%) Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTL----V 453 P I P++ + C A+ P P I WY G L + RR V +G+L V Sbjct: 16 PRIQEHPADAVAAKEEPLTLNCKAVGRPPPDINWYHNGVPLGPSDRRVVLPEGSLFFLKV 75 Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGP 506 +++ + D+G Y C A + G V A L + + V+ + GP Sbjct: 76 MQNKREQDAGVYHCEAHNSAGVAVSRNATLQIAMLKDEFRAMPKDTVALVGGP 128 Score = 36.7 bits (81), Expect = 3.9 Identities = 17/41 (41%), Positives = 22/41 (53%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRW 45 Y+ EAP +E P+DV + + TL CRA G P I W Sbjct: 287 YLYVYEAPTFMEAPVDVVIREGEGITLPCRAKGRPGVRIFW 327 >UniRef50_UPI00006A0174 Cluster: Roundabout homolog 4 precursor (Magic roundabout).; n=1; Xenopus tropicalis|Rep: Roundabout homolog 4 precursor (Magic roundabout). - Xenopus tropicalis Length = 1082 Score = 237 bits (580), Expect = 1e-60 Identities = 126/287 (43%), Positives = 166/287 (57%), Gaps = 10/287 (3%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT----HRSI--LPAGG 65 P IIE P D+ V + +PATL CRA G+P P I WY+ G V + T RS LP G Sbjct: 11 PRIIEHPSDLFVKKDKPATLYCRAEGNPQPTIEWYRNGEHVETSTDDKTQRSYVQLPEGP 70 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 LFF + SD G+Y C A N GTA SRNA+L+VA LR++FRL P A G + Sbjct: 71 LFFFSLNQRKGKSDEGIYTCVARNHLGTAFSRNASLYVAALRDDFRLNPSDAVVAVGKQL 130 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 +ECLPP+G PEPNV WKK+G + + ++ + + G L I A +TD+G Y C+A N Sbjct: 131 EIECLPPKGHPEPNVTWKKDG--IPINHNNSRYTISAGKLFIGKALKTDSGLYSCLASNQ 188 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 G RES A + + KP P DV A+ GS+V F C GDP P W S G++P Sbjct: 189 VGERESRAAKIVVLEKPMFTYKPSDVTAKFGSTVQFGCGAQGDPKPTFHW--SKENGDLP 246 Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292 GR ++ ++ +LR+ +V L D G+Y C A N + VSA LTV DP Sbjct: 247 QGRYEITNENTLRIRSVTLYDSGKYICTAGNQLETVSAKALLTVQDP 293 Score = 92.7 bits (220), Expect = 6e-17 Identities = 61/207 (29%), Positives = 93/207 (44%), Gaps = 12/207 (5%) Query: 134 GSPEPNVYWKKNGQTLLFDGDSR-----MHLVDGGNLVI---QDARQTDAGRYQCIARNA 185 G+P+P + W +NG+ + D + + L +G Q ++D G Y C+ARN Sbjct: 36 GNPQPTIEWYRNGEHVETSTDDKTQRSYVQLPEGPLFFFSLNQRKGKSDEGIYTCVARNH 95 Query: 186 AGTRESAIATLKIH-IKPYLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGN 243 GT S A+L + ++ P D V G + +C G P P+V W++ N Sbjct: 96 LGTAFSRNASLYVAALRDDFRLNPSDAVVAVGKQLEIECLPPKGHPEPNVTWKKDGIPIN 155 Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSV 302 R + G L + + D G YSC A N VG S + + V + P P+ V Sbjct: 156 HNNSRYTI-SAGKLFIGKALKTDSGLYSCLASNQVGERESRAAKIVVLEKPMFTYKPSDV 214 Query: 303 NVESGNVARFTCTATGRPEPTMFWSVE 329 + G+ +F C A G P+PT WS E Sbjct: 215 TAKFGSTVQFGCGAQGDPKPTFHWSKE 241 Score = 78.2 bits (184), Expect = 1e-12 Identities = 87/320 (27%), Positives = 141/320 (44%), Gaps = 24/320 (7%) Query: 636 VELIEATPIDSKTIKLMWEILNFY-YLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEI 694 V L T + S ++ + W++L + EG +++R L + E+ T N+ S I Sbjct: 314 VHLDNITALPSASVYVHWQVLTESPFTEGYSVFYRTLSSTESEWTEWTKSRINEYSTV-I 372 Query: 695 TSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILN--TTTVHLKW 752 SL + KYEF + PF K G SN + + ++VP+ P NI + + T+ + W Sbjct: 373 PSLWRGQKYEFKIRPFAGKNYGPDSNIKHLRIPEEVPNIAPQNINVTAVEGGNGTIVVSW 432 Query: 753 SPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT-SLIMTNLTSGVSYSVQIA 811 PP + + I GY V W N++ + V + T SL + L SG+ Y VQ+A Sbjct: 433 EPPPKNIHSSNIKGYKV---WCF--ENETHPKADWIVDEETKSLEIPMLASGIKYQVQVA 487 Query: 812 AETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETWFYFLIGAIVLF 871 A G+G S Y IDS V + + E+ + V F +G + Sbjct: 488 AINDAGIGMPSIPKYIMIDSPEV--KEVKDENIYFELIL---QVVRHPAFIGTVGTVAWI 542 Query: 872 KIIVIAGIIYVRKYNIFAKK--SALPNI---YDSNGTSLVTQMNIKAAVSLSH--PLTSC 924 ++V A + R ++ K S L N + S T + +M+I + LSH SC Sbjct: 543 LLMVAAVYVCQRHSKRYSTKQHSILGNSLYRFASEDTIIKHRMDISDSPWLSHTWKSASC 602 Query: 925 YN--KNTVTKTESLLWMENQ 942 +T++ LLW E + Sbjct: 603 SRNYSSTISMNSQLLWSETK 622 Score = 76.6 bits (180), Expect = 4e-12 Identities = 83/301 (27%), Positives = 117/301 (38%), Gaps = 29/301 (9%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG----GGNMPLGRVKV-LDDGS 256 P +I P D+ + T CR G+P P + W R+ + R V L +G Sbjct: 11 PRIIEHPSDLFVKKDKPATLYCRAEGNPQPTIEWYRNGEHVETSTDDKTQRSYVQLPEGP 70 Query: 257 LRLDNVIL----ADEGEYSCEAENSVGAV---SASGYLTVYDPPSINLSPNSVNVESGNV 309 L ++ +DEG Y+C A N +G +AS Y+ L+P+ V G Sbjct: 71 LFFFSLNQRKGKSDEGIYTCVARNHLGTAFSRNASLYVAALRD-DFRLNPSDAVVAVGKQ 129 Query: 310 ARFTCTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368 C G PEP + W +G I SR A +F G + K DS Sbjct: 130 LEIECLPPKGHPEPNVTWKKDG--IPINHNNSRYTISAGKLFIGKAL-------KTDS-G 179 Query: 369 TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428 C A N G R V + P+ T PS+ T S F C A P+P Sbjct: 180 LYSCLASNQVGERESRAAKIVVLEK----PMFTYKPSDVTAKFGSTVQFGCGAQGDPKPT 235 Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPI 488 W E L Q R +TN+ TL ++ + DSG Y C A ++ L V P+ Sbjct: 236 FHWSKENGDLPQG-RYEITNENTLRIRSVTLYDSGKYICTAGNQLETVSAKALLTVQDPL 294 Query: 489 N 489 + Sbjct: 295 D 295 Score = 64.1 bits (149), Expect = 2e-08 Identities = 55/241 (22%), Positives = 94/241 (39%), Gaps = 12/241 (4%) Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 PP I P+ + V+ A C A G P+PT+ W G + + Sbjct: 10 PPRIIEHPSDLFVKKDKPATLYCRAEGNPQPTIEWYRNGEHVETSTDDKTQRSYVQLPEG 69 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK---LTVTSDDDRPPPIITNGPSNQT 408 + ++N C A N+ G++F R + DD R PS+ Sbjct: 70 PLFFFSLNQRKGKSDEGIYTCVARNHLGTAFSRNASLYVAALRDDFRL------NPSDAV 123 Query: 409 LPIKSMAVFPCTAICT-PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467 + + C PEP + W +G + N+ R + G L + K+DSG Y+C Sbjct: 124 VAVGKQLEIECLPPKGHPEPNVTWKKDGIPINHNNSRYTISAGKLFIGKALKTDSGLYSC 183 Query: 468 VASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527 +AS++ G+ A +V + + ++ +DV++ G + D T WS+ Sbjct: 184 LASNQVGERESRAAKIV--VLEKPMFTYKPSDVTAKFGSTVQFGCGAQGDPKPTFHWSKE 241 Query: 528 N 528 N Sbjct: 242 N 242 >UniRef50_Q71B05 Cluster: Roundabout-like protein 4; n=5; Danio rerio|Rep: Roundabout-like protein 4 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 1134 Score = 227 bits (554), Expect = 2e-57 Identities = 121/286 (42%), Positives = 157/286 (54%), Gaps = 10/286 (3%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-----THRSILPAGGL 66 P I+ P DV V PATL+CRA G+P P I+W + G + +D + +LP G L Sbjct: 71 PRIVHHPSDVVVRVGSPATLSCRAEGNPEPTIQWLRNGQPLDTDKMDAQSQPIVLPDGSL 130 Query: 67 FFLRATHGRV-HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 FF GR S VY C A NS G A SRNA+LH+A LRE+FR++P + A G+ Sbjct: 131 FFFSVVPGRKGQSHEAVYACIAHNSIGNATSRNASLHIAALREDFRVQPSDVEVAIGEMA 190 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 + C PP G PEPNV W+K+G +L + + + G L+I A++ D+G Y CIA N Sbjct: 191 TINCSPPVGHPEPNVTWRKDG--ILINSSNEHYTELKGKLIIAPAQKNDSGVYSCIASNM 248 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 G RES A L + KP L+ PEDV Q G S F C GDP+P + W R G +P Sbjct: 249 IGVRESRAARLSVLAKPVLLRKPEDVSVQLGESAQFFCEADGDPMPSIEWSREQ--GPLP 306 Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291 GR + D SL++ V D G YSC EN +G AS L V D Sbjct: 307 NGRYLINPDHSLQIHYVTAQDMGRYSCTVENKLGVSVASAQLLVED 352 Score = 94.7 bits (225), Expect = 1e-17 Identities = 123/430 (28%), Positives = 181/430 (42%), Gaps = 52/430 (12%) Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242 R+ A R+ + +I++ P ++ P DVV + GS T CR G+P P + W R+ Sbjct: 53 RDRAHRRKGSRLVSEINL-PRIVHHPSDVVVRVGSPATLSCRAEGNPEPTIQWLRNG--- 108 Query: 243 NMPLGRVK--------VLDDGSLRLDNVILADEGE-----YSCEAENSVG-AVSASGYLT 288 PL K VL DGSL +V+ +G+ Y+C A NS+G A S + L Sbjct: 109 -QPLDTDKMDAQSQPIVLPDGSLFFFSVVPGRKGQSHEAVYACIAHNSIGNATSRNASLH 167 Query: 289 VYD-PPSINLSPNSVNVESGNVARFTCTA-TGRPEPTMFWSVEGNRTIIFPGMSRDKYHA 346 + + P+ V V G +A C+ G PEP + W +G I S + Y Sbjct: 168 IAALREDFRVQPSDVEVAIGEMATINCSPPVGHPEPNVTWRKDG----ILINSSNEHY-- 221 Query: 347 TAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG-KLTVTSDDDRPPPIITNGPS 405 G L I KNDS C A N G R +L+V + P++ P Sbjct: 222 -TELKGK--LIIAPAQKNDS-GVYSCIASNMIGVRESRAARLSVLAK-----PVLLRKPE 272 Query: 406 NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465 + ++ + A F C A P P I W E + + N R + D +L + + D G Y Sbjct: 273 DVSVQLGESAQFFCEADGDPMPSIEWSRE-QGPLPNGRYLINPDHSLQIHYVTAQDMGRY 331 Query: 466 TCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWS 525 +C ++ G V S LLV+ + ++S+L + NVT S + S Sbjct: 332 SCTVENKLGVSVASAQLLVEDAGGTRLRDLH-KELSAL-----RVSLENVTVMSTASNMS 385 Query: 526 QNN-KIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQ--THYVVKSLIPGIT 582 Q K+ S + +E F E L + P +S W A+RV Q H V L G Sbjct: 386 QVMWKLQSFGSQPHYLEGF--EVLYRSLLPASS-DWT--AQRVPQPSLHTHVGPLKRGYK 440 Query: 583 YMFIVRTENS 592 Y F VR S Sbjct: 441 YEFKVRPYGS 450 Score = 89.4 bits (212), Expect = 5e-16 Identities = 76/243 (31%), Positives = 105/243 (43%), Gaps = 18/243 (7%) Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTL---LFDGDSRMHLVDGGNL----VIQDAR-QT 173 G L C G+PEP + W +NGQ L D S+ ++ G+L V+ + Q+ Sbjct: 85 GSPATLSCRA-EGNPEPTIQWLRNGQPLDTDKMDAQSQPIVLPDGSLFFFSVVPGRKGQS 143 Query: 174 DAGRYQCIARNAAGTRESAIATLKIH-IKPYLITGPEDVVAQTGSSVTFQCRVG-GDPLP 231 Y CIA N+ G S A+L I ++ P DV G T C G P P Sbjct: 144 HEAVYACIAHNSIGNATSRNASLHIAALREDFRVQPSDVEVAIGEMATINCSPPVGHPEP 203 Query: 232 DVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVY 290 +V WR+ N L G L + D G YSC A N +G S + L+V Sbjct: 204 NVTWRKDGILINSSNEHYTELK-GKLIIAPAQKNDSGVYSCIASNMIGVRESRAARLSVL 262 Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVE-----GNRTIIFPGMSRDKYH 345 P + P V+V+ G A+F C A G P P++ WS E R +I P S ++ Sbjct: 263 AKPVLLRKPEDVSVQLGESAQFFCEADGDPMPSIEWSREQGPLPNGRYLINPDHSLQIHY 322 Query: 346 ATA 348 TA Sbjct: 323 VTA 325 Score = 72.1 bits (169), Expect = 8e-11 Identities = 63/240 (26%), Positives = 106/240 (44%), Gaps = 20/240 (8%) Query: 646 SKTIKLMWEILNF----YYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYT 701 S ++MW++ +F +YLEG + +R L + ++ + + + + + L++ Sbjct: 382 SNMSQVMWKLQSFGSQPHYLEGFEVLYRSLLPASSDWTAQRVPQPSLHT--HVGPLKRGY 439 Query: 702 KYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPP--INIEMFILNTTTVHLKWSPPELQL 759 KYEF + P+ G+ SN+R + + VP P ++I M TVHL W PP Sbjct: 440 KYEFKVRPYGSSLYGRESNTRHLRVPEIVPSAAPQDVSITMPAERNDTVHLSWEPPPHDA 499 Query: 760 QNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT-SLIMTNLTSGVSYSVQIAAETIIGL 818 NGII GY V W ++ + N TV T S+ + L Y V +AA G+ Sbjct: 500 HNGIIQGYQV---W--CVESEEQTSFNWTVDSGTHSIEIVTLLPSRLYWVSVAAVNGAGV 554 Query: 819 GPFSQKVYFNIDSR------SVGLDLLSRYPMNGEVSIVAGDFVMETWFYFLIGAIVLFK 872 G S I+SR G+ +S + + + G W +I A+ L++ Sbjct: 555 GVQSDPYKLLIESRLEATPYQTGILSMSHFVSVIKEPVFIGSVGTLLWCVLMITAVFLYR 614 >UniRef50_Q4SCT9 Cluster: Chromosome 7 SCAF14650, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 7 SCAF14650, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1450 Score = 219 bits (536), Expect = 3e-55 Identities = 139/443 (31%), Positives = 227/443 (51%), Gaps = 27/443 (6%) Query: 394 DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGTL 452 D PPP+I GP NQT+P+ S V C A+ P P+I W +G L + R ++T+ G+L Sbjct: 317 DHPPPVIKRGPLNQTVPVDSTVVLSCHAVGIPPPVIHWKKDGVVLSPADSRMSITDMGSL 376 Query: 453 VLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPIT 512 ++ D+G+YTCVA+S +G+ W+ L V+ + AD++ +PG P+KP Sbjct: 377 EIRYAKLGDTGSYTCVATSPNGEASWTAHLQVEGRVWSCCSLRPPADLNLIPGAPSKPEV 436 Query: 513 HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHY 572 ++T TSV L+W N G++ Y +E FS TL WV + V + Sbjct: 437 TDITRTSVMLTWKSNQSSGAAPT-SYLIEAFSY-TLGSR--------WVTLVEHVKTDTF 486 Query: 573 VVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILT 632 V+K+L P Y+F+VR NSHG+S PSP++DSV D +++ GV + + L Sbjct: 487 VLKNLRPATVYLFMVRAVNSHGISDPSPITDSVRTQDSPSTI---PGVDH--RHIQKELG 541 Query: 633 DHIVELIEATPIDSKTIKLMWEI-LNFYYLEGLFIYFRP-LDNITIEYEMKTI-LHSNDV 689 D +V L T + S ++L W + Y++G +++RP D+ E + + + + Sbjct: 542 DVVVHLHTPTIVSSSAVRLQWVVEQQSPYIQGYKVFYRPSADHGQPEGQWSIVEVQAPRD 601 Query: 690 SGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPP--INIEMFILNTTT 747 G I L+ + YEF + PF+ +F+G S +V +T +D P P + + +N T Sbjct: 602 DGVVIGQLKGGSIYEFKVRPFFDEFQGADSEVKVVRTSEDAPKRAPQDVTVTKSDVNGTA 661 Query: 748 VHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT-SLIMTNLTSGVSY 806 + + W PP G I Y + W N+S +N +V +T S+++ +L G+ Y Sbjct: 662 ILVAWKPPLEWEDTGRIQEYKI---W--CLGNESRYHVNQSVDGSTLSVVIPSLAPGIRY 716 Query: 807 SVQIAAETIIGLGPFSQKVYFNI 829 SV++AA G G S +F + Sbjct: 717 SVEVAASNGAGPGVKSDATFFQL 739 Score = 211 bits (516), Expect = 8e-53 Identities = 109/287 (37%), Positives = 156/287 (54%), Gaps = 6/287 (2%) Query: 104 AVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG 163 ++LR++FR P A G+ VLEC PPRG PEP + W+++G L D D R+ + G Sbjct: 3 SILRDDFRQNPVDVMVAVGEPAVLECQPPRGHPEPTISWRRDGANLN-DKDERI-TIRSG 60 Query: 164 NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223 L+I + +++DAG+Y C+ N G RES IA L + +P + P VV SV F C Sbjct: 61 KLMITNTKKSDAGKYICVGTNMVGERESEIAELTVLERPTFVKRPRSVVVLAEESVKFHC 120 Query: 224 RVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSA 283 V GDP+P V WR+ ++P GR ++LDD +L + V DEG Y+C EN VG A Sbjct: 121 VVQGDPVPTVRWRKD--DSDLPKGRFEILDDHTLNIRQVTSVDEGSYTCVVENMVGKSEA 178 Query: 284 SGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDK 343 S LTV+ PP+ + P + G + F C ATG P+P +FW EG+ +++F Sbjct: 179 SATLTVHVPPAFAVRPRNQEAAVGRIVTFQCEATGNPQPAIFWQKEGSESLLFSYQPPQP 238 Query: 344 YHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT 390 + +V LTI + +DS C A+N AGS + L VT Sbjct: 239 FSRLSV-SQTGSLTITNVQHSDS-GFYSCQALNIAGSVITKALLEVT 283 Score = 139 bits (336), Expect = 5e-31 Identities = 92/284 (32%), Positives = 126/284 (44%), Gaps = 18/284 (6%) Query: 16 EQPLDVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74 + P+DV VA +PA L C+ G P P I W + G + R + +G L Sbjct: 11 QNPVDVMVAVGEPAVLECQPPRGHPEPTISWRRDGANLNDKDERITIRSGKLMITNTKK- 69 Query: 75 RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRG 134 SDAG Y C TN G S A L V + R F P S ++V C+ +G Sbjct: 70 ---SDAGKYICVGTNMVGERESEIAELTV-LERPTFVKRPRSVVVLAEESVKFHCVV-QG 124 Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194 P P V W+K+ L R ++D L I+ D G Y C+ N G E++ A Sbjct: 125 DPVPTVRWRKDDSDL---PKGRFEILDDHTLNIRQVTSVDEGSYTCVVENMVGKSEAS-A 180 Query: 195 TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM-------PLG 247 TL +H+ P P + A G VTFQC G+P P + W++ + P Sbjct: 181 TLTVHVPPAFAVRPRNQEAAVGRIVTFQCEATGNPQPAIFWQKEGSESLLFSYQPPQPFS 240 Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291 R+ V GSL + NV +D G YSC+A N G+V L V D Sbjct: 241 RLSVSQTGSLTITNVQHSDSGFYSCQALNIAGSVITKALLEVTD 284 Score = 97.1 bits (231), Expect = 3e-18 Identities = 81/287 (28%), Positives = 119/287 (41%), Gaps = 27/287 (9%) Query: 208 PEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILAD 266 P DV+ G +C+ G P P + WRR N R+ + G L + N +D Sbjct: 13 PVDVMVAVGEPAVLECQPPRGHPEPTISWRRDGANLNDKDERITIRS-GKLMITNTKKSD 71 Query: 267 EGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325 G+Y C N VG S LTV + P+ P SV V + +F C G P PT+ Sbjct: 72 AGKYICVGTNMVGERESEIAELTVLERPTFVKRPRSVVVLAEESVKFHCVVQGDPVPTVR 131 Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385 W + + + + ++ + D T L I D + C N G S Sbjct: 132 WRKDDS------DLPKGRFE---ILDDHT-LNIRQVTSVDE-GSYTCVVENMVGKSEASA 180 Query: 386 KLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG-EALIQNH-- 442 LTV PP P NQ + + F C A P+P I W EG E+L+ ++ Sbjct: 181 TLTV-----HVPPAFAVRPRNQEAAVGRIVTFQCEATGNPQPAIFWQKEGSESLLFSYQP 235 Query: 443 -----RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 R +V+ G+L + ++ SDSG Y+C A + G + L V Sbjct: 236 PQPFSRLSVSQTGSLTITNVQHSDSGFYSCQALNIAGSVITKALLEV 282 Score = 76.2 bits (179), Expect = 5e-12 Identities = 55/185 (29%), Positives = 87/185 (47%), Gaps = 14/185 (7%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P +++P V V + +C G P P +RW K + IL L Sbjct: 97 ERPTFVKRPRSVVVLAEESVKFHCVVQGDPVPTVRWRKDDSDLPKGRF-EILDDHTLNIR 155 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 + T D G Y C N G + + +ATL V V F + P ++++A G V +C Sbjct: 156 QVT----SVDEGSYTCVVENMVGKSEA-SATLTVHV-PPAFAVRPRNQEAAVGRIVTFQC 209 Query: 130 LPPRGSPEPNVYWKKNG-QTLLFDGD-----SRMHLVDGGNLVIQDARQTDAGRYQCIAR 183 G+P+P ++W+K G ++LLF SR+ + G+L I + + +D+G Y C A Sbjct: 210 -EATGNPQPAIFWQKEGSESLLFSYQPPQPFSRLSVSQTGSLTITNVQHSDSGFYSCQAL 268 Query: 184 NAAGT 188 N AG+ Sbjct: 269 NIAGS 273 Score = 52.4 bits (120), Expect = 7e-05 Identities = 50/192 (26%), Positives = 74/192 (38%), Gaps = 18/192 (9%) Query: 298 SPNSVNVESGNVARFTCTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356 +P V V G A C G PEPT+ W +G DK + G ++ Sbjct: 12 NPVDVMVAVGEPAVLECQPPRGHPEPTISWRRDGANL-------NDKDERITIRSGKLMI 64 Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVR-GKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415 T +T K+D+ +C N G +LTV P P + + + Sbjct: 65 T--NTKKSDA-GKYICVGTNMVGERESEIAELTVLER-----PTFVKRPRSVVVLAEESV 116 Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 F C P P + W + L + R + +D TL ++ + D G+YTCV + GK Sbjct: 117 KFHCVVQGDPVPTVRWRKDDSDLPKG-RFEILDDHTLNIRQVTSVDEGSYTCVVENMVGK 175 Query: 476 YVWSGALLVDSP 487 S L V P Sbjct: 176 SEASATLTVHVP 187 Score = 52.4 bits (120), Expect = 7e-05 Identities = 28/64 (43%), Positives = 38/64 (59%), Gaps = 2/64 (3%) Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183 TVVL C G P P ++WKK+G +L DSRM + D G+L I+ A+ D G Y C+A Sbjct: 337 TVVLSCHAV-GIPPPVIHWKKDG-VVLSPADSRMSITDMGSLEIRYAKLGDTGSYTCVAT 394 Query: 184 NAAG 187 + G Sbjct: 395 SPNG 398 Score = 47.6 bits (108), Expect = 0.002 Identities = 33/84 (39%), Positives = 38/84 (45%), Gaps = 5/84 (5%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLFFLR 70 P I PL+ TV L+C A G P P I W K G VL +D+ SI G L Sbjct: 321 PVIKRGPLNQTVPVDSTVVLSCHAVGIPPPVIHWKKDGVVLSPADSRMSITDMGSLEIRY 380 Query: 71 ATHGRVHSDAGVYWCEATNSYGTA 94 A G D G Y C AT+ G A Sbjct: 381 AKLG----DTGSYTCVATSPNGEA 400 Score = 46.8 bits (106), Expect = 0.004 Identities = 26/91 (28%), Positives = 40/91 (43%) Query: 199 HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLR 258 H P + GP + S+V C G P P + W++ + R+ + D GSL Sbjct: 318 HPPPVIKRGPLNQTVPVDSTVVLSCHAVGIPPPVIHWKKDGVVLSPADSRMSITDMGSLE 377 Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTV 289 + L D G Y+C A + G S + +L V Sbjct: 378 IRYAKLGDTGSYTCVATSPNGEASWTAHLQV 408 >UniRef50_UPI000065EA6D Cluster: Homolog of Brachydanio rerio "Roundabout-like protein 4.; n=1; Takifugu rubripes|Rep: Homolog of Brachydanio rerio "Roundabout-like protein 4. - Takifugu rubripes Length = 1100 Score = 219 bits (534), Expect = 5e-55 Identities = 122/290 (42%), Positives = 163/290 (56%), Gaps = 10/290 (3%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSI----LPAGG 65 AP I+ P DV V PA L+CRA GSP ++ W + G L +S + LP G Sbjct: 71 APSIVHHPSDVVVKPGNPAQLSCRAEGSPQVSLEWLQNGQPLQMSKADGQMQPIMLPEGS 130 Query: 66 LFFLRATHG-RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124 LFFL G R S GVY C A N+ GTA SRNA+L +AVL+EEF ++P + A+G+ Sbjct: 131 LFFLSVGEGPRGPSHEGVYACVARNAVGTAISRNASLRIAVLQEEFHVQPSDVEVAEGEV 190 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 VL C PP G PEPNV WKK+G + + D ++ G L++ A + ++G Y C+A N Sbjct: 191 AVLNCGPPTGRPEPNVLWKKDGVPVNIN-DPHFTVL-SGKLIVAPAEKQNSGSYVCVATN 248 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 G RES A L + KP L+ PE+V + G S F C+ GDP P V+W R G + Sbjct: 249 TVGVRESRAARLSVLAKPTLLLKPENVSVKLGESAQFYCQAKGDPPPTVVWSREQ--GPL 306 Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294 P GR V + +L++ V D G Y+C A N VG V+AS L V + PS Sbjct: 307 PNGRYLVNPNQTLQIHYVTAQDAGLYTCTAANDVGVVTASAQLLVEEAPS 356 Score = 97.9 bits (233), Expect = 1e-18 Identities = 79/256 (30%), Positives = 117/256 (45%), Gaps = 19/256 (7%) Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLF---DGDSRMHLVDGGNLVIQDARQ-----T 173 G+ L C GSP+ ++ W +NGQ L DG + ++ G+L + + Sbjct: 86 GNPAQLSCRA-EGSPQVSLEWLQNGQPLQMSKADGQMQPIMLPEGSLFFLSVGEGPRGPS 144 Query: 174 DAGRYQCIARNAAGTRESAIATLKIHI-KPYLITGPEDVVAQTGSSVTFQCRVG-GDPLP 231 G Y C+ARNA GT S A+L+I + + P DV G C G P P Sbjct: 145 HEGVYACVARNAVGTAISRNASLRIAVLQEEFHVQPSDVEVAEGEVAVLNCGPPTGRPEP 204 Query: 232 DVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVY 290 +VLW++ N+ VL G L + + G Y C A N+VG S + L+V Sbjct: 205 NVLWKKDGVPVNINDPHFTVLS-GKLIVAPAEKQNSGSYVCVATNTVGVRESRAARLSVL 263 Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVE-----GNRTIIFPGMSRDKYH 345 P++ L P +V+V+ G A+F C A G P PT+ WS E R ++ P + ++ Sbjct: 264 AKPTLLLKPENVSVKLGESAQFYCQAKGDPPPTVVWSREQGPLPNGRYLVNPNQTLQIHY 323 Query: 346 ATAVFDGV-TVLTIND 360 TA G+ T ND Sbjct: 324 VTAQDAGLYTCTAAND 339 Score = 90.6 bits (215), Expect = 2e-16 Identities = 89/299 (29%), Positives = 134/299 (44%), Gaps = 29/299 (9%) Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL--GRVK--VLDDG 255 I P ++ P DVV + G+ CR G P + W ++ M G+++ +L +G Sbjct: 70 IAPSIVHHPSDVVVKPGNPAQLSCRAEGSPQVSLEWLQNGQPLQMSKADGQMQPIMLPEG 129 Query: 256 SLRLDNV-----ILADEGEYSCEAENSVG-AVSASGYLTV-YDPPSINLSPNSVNVESGN 308 SL +V + EG Y+C A N+VG A+S + L + ++ P+ V V G Sbjct: 130 SLFFLSVGEGPRGPSHEGVYACVARNAVGTAISRNASLRIAVLQEEFHVQPSDVEVAEGE 189 Query: 309 VARFTC-TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367 VA C TGRPEP + W +G P D H T V G L + +K +S Sbjct: 190 VAVLNCGPPTGRPEPNVLWKKDG-----VPVNINDP-HFT-VLSG--KLIVAPAEKQNS- 239 Query: 368 NTIVCSAVNYAGSSFVR-GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426 + VC A N G R +L+V + P + P N ++ + A F C A P Sbjct: 240 GSYVCVATNTVGVRESRAARLSVLA-----KPTLLLKPENVSVKLGESAQFYCQAKGDPP 294 Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485 P + W E + + N R V + TL + + D+G YTC A++ G S LLV+ Sbjct: 295 PTVVWSRE-QGPLPNGRYLVNPNQTLQIHYVTAQDAGLYTCTAANDVGVVTASAQLLVE 352 Score = 62.1 bits (144), Expect = 9e-08 Identities = 43/163 (26%), Positives = 74/163 (45%), Gaps = 8/163 (4%) Query: 659 YYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKP 718 +YL+G + +R L + ++ K + + + L++ KYEF + P+ G+ Sbjct: 400 HYLDGFEVLYRSLLPASSDWAAKKVTMPSFQC--HLGPLKRGFKYEFKVRPYGSNLYGRE 457 Query: 719 SNSRVAQTLDDVPDGPP--INIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDV 776 SN++ + + VP P ++I + T+HL W PP L NGI+ GY V W V Sbjct: 458 SNTQHLRVPETVPSASPQTVSISVSRQQNNTIHLSWEPPPLDTHNGILQGYQV---WC-V 513 Query: 777 PANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819 + + T L ++ L G Y + +AA G+G Sbjct: 514 ESEEERYQNWTVNSSQQKLDISALKPGKQYWITVAAVNGAGVG 556 >UniRef50_Q96RW7 Cluster: Hemicentin-1 precursor; n=40; Eumetazoa|Rep: Hemicentin-1 precursor - Homo sapiens (Human) Length = 5635 Score = 206 bits (502), Expect = 4e-51 Identities = 153/481 (31%), Positives = 219/481 (45%), Gaps = 30/481 (6%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFF 68 E P I QP ++ V + P L C A G+PSP I W K G+ V S + ++LP+GGL Sbjct: 3986 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQI 4045 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS--AQGDTVV 126 RA V DAG Y C A N GTA + L+V V + P K+ A + Sbjct: 4046 SRA----VREDAGTYMCVAQNPAGTALGK-IKLNVQVPPV---ISPHLKEYVIAVDKPIT 4097 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186 L C G P P++ W K+G+ ++ R ++ G+L I + DAG Y C+A N A Sbjct: 4098 LSC-EADGLPPPDITWHKDGRAIV--ESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVA 4154 Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 G+ S L +H+ P + + S C G P P + W++ L Sbjct: 4155 GS-SSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLL 4213 Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306 G+ G L L+NV+L D G Y+C A N+ G + + LTV+ P+ P V++ Sbjct: 4214 GKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNK 4273 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 G R +C ATG P P + W+ N I P H +V +G + L I K DS Sbjct: 4274 GEQLRLSCKATGIPLPKLTWTFNNN---IIPA------HFDSV-NGHSELVIERVSKEDS 4323 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426 T VC+A N G G + V PP + PSN P+ A+ C P Sbjct: 4324 -GTYVCTAENSVGFVKAIGFVYVKE----PPVFKGDYPSNWIEPLGGNAILNCEVKGDPT 4378 Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486 P I W +G + +HR +G+L + D+G YTCVA++ G S +L + S Sbjct: 4379 PTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQS 4438 Query: 487 P 487 P Sbjct: 4439 P 4439 Score = 187 bits (456), Expect = 1e-45 Identities = 147/478 (30%), Positives = 210/478 (43%), Gaps = 28/478 (5%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV--SDTHRSILPAGGLFFL 69 P I ++P D V +H PA + C A G P P+I W K G+ ++ D +R IL +G + L Sbjct: 3897 PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYR-ILSSGAIEIL 3955 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 AT + AG Y C A N+ G+A R+ TLHV + +P + ++L C Sbjct: 3956 -ATQ---LNHAGRYTCVARNAAGSAH-RHVTLHVHE-PPVIQPQPSELHVILNNPILLPC 4009 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189 G+P P + W+K G + G + L GG L I A + DAG Y C+A+N AGT Sbjct: 4010 -EATGTPSPFITWQKEGINVNTSGRNHAVLPSGG-LQISRAVREDAGTYMCVAQNPAGTA 4067 Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249 I L + + P + ++ V +T C G P PD+ W + G + R Sbjct: 4068 LGKIK-LNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKD-GRAIVESIRQ 4125 Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309 +VL GSL++ V D G Y+C A N G+ S S LTV+ PP I + V + Sbjct: 4126 RVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQ 4185 Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369 A C A G P P + W + ++ + KY A + L + + DS Sbjct: 4186 AILPCVADGIPTPAINWKKD---NVLLANL-LGKYTAEPYGE----LILENVVLEDS-GF 4236 Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429 C A N AG LTV P T P + +L C A P P + Sbjct: 4237 YTCVANNAAGEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKL 4291 Query: 430 AWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 W F +I H +V LV++ + K DSGTY C A + G G + V P Sbjct: 4292 TWTFNNN-IIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEP 4348 Score = 186 bits (452), Expect = 4e-45 Identities = 151/574 (26%), Positives = 247/574 (43%), Gaps = 34/574 (5%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 +T P I P + + ++ L C A G P+P I W K G ++ + R + G Sbjct: 3707 LTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENG 3766 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 +++ H +D G Y C ATN+ GT R R L V V P + Sbjct: 3767 FLHIQSAH---VTDTGRYLCMATNAAGTDR-RRIDLQVHV-PPSIAPGPTNMTVIVNVQT 3821 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH-LVDGGNLVIQDARQTDAGRYQCIARN 184 L C G P+P++ W+KNG L D + + L+ G+LVI D Y+C N Sbjct: 3822 TLAC-EATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTN 3880 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 AG + + L + + P + P D + + C G P P + W ++ G + Sbjct: 3881 GAGDDKRTV-DLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKN-GIRLL 3938 Query: 245 PLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303 P G ++L G++ + L G Y+C A N+ G+ L V++PP I P+ ++ Sbjct: 3939 PRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELH 3998 Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363 V N C ATG P P + W EG + + HA G L I+ + Sbjct: 3999 VILNNPILLPCEATGTPSPFITWQKEGINV-----NTSGRNHAVLPSGG---LQISRAVR 4050 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423 D+ T +C A N AG++ + KL V + PP+I+ + + C A Sbjct: 4051 EDA-GTYMCVAQNPAGTALGKIKLNV-----QVPPVISPHLKEYVIAVDKPITLSCEADG 4104 Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483 P P I W+ +G A++++ R+ V + G+L + + D+G YTC+A++ G S L Sbjct: 4105 LPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLT 4164 Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVT--LSWSQNNKIGSSSILGYQVE 541 V P P I R+ + ++ I V D T ++W ++N + ++ + Y E Sbjct: 4165 VHVP--PRI---RSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAE 4219 Query: 542 VFSRETLSGNNTPRNSRGWVVIARRV--HQTHYV 573 + E + N +S + +A TH V Sbjct: 4220 PYG-ELILENVVLEDSGFYTCVANNAAGEDTHTV 4252 Score = 182 bits (442), Expect = 7e-44 Identities = 137/480 (28%), Positives = 205/480 (42%), Gaps = 35/480 (7%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-----SDTHRSILPA 63 G P I++P DV++ TL C G P P I+W + + + S + S L Sbjct: 790 GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRT 849 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123 G LF L SD G Y CEA N +G +S ++ + P +G Sbjct: 850 GALFILNLW----ASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQ 905 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183 + L C G+P P W KN LL + + + G+L I+ + D G Y C+A Sbjct: 906 QLTLPCTLLAGNPIPERRWIKNSAMLL--QNPYITVRSDGSLHIERVQLQDGGEYTCVAS 963 Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 N AGT + + +H+ P + G + + G VT C+ G+P P V+W + + Sbjct: 964 NVAGTNNKTTSVV-VHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIS 1022 Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-----NLS 298 + DGSL + + + GEY C A N+ G LTVY P + LS Sbjct: 1023 TSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLS 1082 Query: 299 ---PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355 P ++V +G C P P + W+ E +I P R + + Sbjct: 1083 QDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKE--TQLISPFSPRHTFLPSG------S 1134 Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415 + I +T +DS +C A N AG+ KL V PP I GP + + + Sbjct: 1135 MKITETRTSDS-GMYLCVATNIAGNVTQAVKLNV-----HVPPKIQRGPKHLKVQVGQRV 1188 Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN-DGTLVLKDLDKSDSGTYTCVASSRHG 474 PC A TP P+I W G ++ + +V+N DGTL + SD+G YTCVA++ G Sbjct: 1189 DIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAG 1248 Score = 177 bits (431), Expect = 2e-42 Identities = 141/487 (28%), Positives = 213/487 (43%), Gaps = 36/487 (7%) Query: 10 EAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68 + P +I L + +A +P TL+C A G P P I W+K G +V + +L +G L Sbjct: 4076 QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQI 4135 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127 G DAG Y C A N G++ S T+HV R + +L Sbjct: 4136 AFVQPG----DAGHYTCMAANVAGSSSTSTKLTVHVP---PRIRSTEGHYTVNENSQAIL 4188 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 C+ G P P + WKK+ LL + + G L++++ D+G Y C+A NAAG Sbjct: 4189 PCVAD-GIPTPAINWKKDN-VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAG 4246 Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247 ++ +L +H+ P P DV G + C+ G PLP + W + +P Sbjct: 4247 -EDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTW--TFNNNIIPAH 4303 Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES- 306 V L ++ V D G Y C AENSVG V A G++ V +PP S +E Sbjct: 4304 FDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPL 4363 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 G A C G P PT+ W+ +G I + + + A++ T+N+ D D Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYG-----TVNE-DAGD- 4416 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426 C A N AG LT+ S PPIIT P + + C A P+ Sbjct: 4417 ---YTCVATNEAGVVERSMSLTLQS-----PPIITLEPVETVINAGGKIILNCQATGEPQ 4468 Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486 P I W +G ++ + R NV ++ +L + D K D+ + CVA + G++LV Sbjct: 4469 PTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARN------LMGSVLVRV 4522 Query: 487 PINPNIH 493 P+ +H Sbjct: 4523 PVIVQVH 4529 Score = 167 bits (406), Expect = 2e-39 Identities = 149/489 (30%), Positives = 207/489 (42%), Gaps = 36/489 (7%) Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-DTHRSILPAGGLFFLRATHG 74 E P DV+V + L C A G P+P I+W K G + S +T R + A G +G Sbjct: 3251 EIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTL--NIYG 3308 Query: 75 RVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133 + SD G Y C ATN G R N ++V + E E + ++ +EC Sbjct: 3309 ALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIEC-RAT 3367 Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193 G+P P + W KNG L R+ L G + I A+ +D Y C+A N AG ++ Sbjct: 3368 GTPPPQINWLKNGLPLPLSSHIRL-LAAGQVIRIVRAQVSDVAVYTCVASNRAGV-DNKH 3425 Query: 194 ATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---R 248 L++ P + G E++ GSS + C G P P + W R PLG Sbjct: 3426 YNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRD----GQPLGLDAH 3481 Query: 249 VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVNVE 305 + V G L+L D G+Y+C A N G VS L V +PP IN S ++V Sbjct: 3482 LTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVI 3541 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365 N TC A+G P P M W +G P D+ G VL I+ D Sbjct: 3542 VNNPLELTCIASGIPAPKMTWMKDGR-----PLPQTDQ---VQTLGGGEVLRISTAQVED 3593 Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIKSMAVFPCTAICT 424 + C A + AG + V PP I T+ P + T+ C + Sbjct: 3594 T-GRYTCLASSPAGDDDKEYLVRV----HVPPNIAGTDEPRDITVLRNRQVTLECKSDAV 3648 Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483 P P+I W GE L R + + G L + + D D+ YTCVAS+ GK L Sbjct: 3649 PPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILT 3708 Query: 484 VDSPINPNI 492 V+ P PNI Sbjct: 3709 VNVP--PNI 3715 Score = 165 bits (402), Expect = 5e-39 Identities = 132/475 (27%), Positives = 213/475 (44%), Gaps = 39/475 (8%) Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGLFFLRATHG 74 EQ +V+V +Q L C G+PSP I WYK V V S T +++ L RAT Sbjct: 1365 EQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATP- 1423 Query: 75 RVHSDAGVYWCEATNSYGTARSR---NATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131 DAG Y C+A N GT++ + + ++ F P V LEC Sbjct: 1424 ---EDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNF---PNEVSVVLNRDVALEC-Q 1476 Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRE 190 +G+P P+++W K+G+ L F GD + L+D G ++ +++AR+ D GRYQC NAAG + Sbjct: 1477 VKGTPFPDIHWFKDGKPL-FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQA 1535 Query: 191 SAIATLKIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248 I L I+I P + G D+ S + +C G P+P + W + G M + Sbjct: 1536 KDI-KLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKD-GQPIMSSSQ 1593 Query: 249 VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NL-SPNSVNV 304 +D G L + ++D Y+C N G S ++ VY PP I NL +P + V Sbjct: 1594 ALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQV 1653 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 + C A G P P + W +G P + D A + +++ + D Sbjct: 1654 VIAHSLTLECKAAGNPSPILTWLKDG-----VPVKANDNIRIEAGGKKLEIMSAQEID-- 1706 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ--TLPIKSMAVFPCTAI 422 R +C A + AG ++ ++ V PP I G + + ++ C Sbjct: 1707 --RGQYICVATSVAGEKEIKYEVDVL-----VPPAIEGGDETSYFIVMVNNLLELDCHVT 1759 Query: 423 CTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKY 476 +P P I W +G+ + + + +G LV+ S++G Y C+A++ G + Sbjct: 1760 GSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDH 1814 Score = 165 bits (402), Expect = 5e-39 Identities = 131/460 (28%), Positives = 211/460 (45%), Gaps = 31/460 (6%) Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS 78 L+ TV P L C+A G+P P I WYK L+ T + L G + + + S Sbjct: 1928 LNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQ---IS 1984 Query: 79 DAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137 DAG+Y C A NS G T + +HVA + V LEC RG P Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVHVA---PSISGSNNMVAVVVNNPVRLEC-EARGIPA 2040 Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197 P++ W K+G + + L G L + A+ +D GRY C+A NAAG ++ I L+ Sbjct: 2041 PSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDI-DLR 2099 Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS- 256 +++ P ++ ++V +V C+ P P + W + G + + + ++ S Sbjct: 2100 VYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKD-GHPLLKKPGLSISENRSV 2158 Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVNVESGNVARFTC 314 L++++ + D G Y+CEA N G + + ++ PP+I S + V GN+ C Sbjct: 2159 LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLC 2218 Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374 ++G P P + W +G+ ++ M R + G L I+ +K+D+ C A Sbjct: 2219 ESSGIPPPNLIWKKKGS-PVLTDSMGR-----VRILSGGRQLQISIAEKSDAA-LYSCVA 2271 Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI----KSMAVFPCTAICTPEPIIA 430 N AG++ L V P ITN S+ T I KS+++ C P P + Sbjct: 2272 SNVAGTAKKEYNLQVYI-----RPTITNSGSHPTEIIVTRGKSISL-ECEVQGIPPPTVT 2325 Query: 431 WYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVA 469 W +G LI+ + ++G L LK++ SD+G Y CVA Sbjct: 2326 WMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVA 2365 Score = 161 bits (391), Expect = 1e-37 Identities = 142/483 (29%), Positives = 205/483 (42%), Gaps = 42/483 (8%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64 ++T E P + P + + ++ C A G P P I W + +V +HR + + Sbjct: 605 FLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVG-SHRYRMTSD 663 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124 G F++ DAG+Y C A+NS GT + +N+TL + + + A GD Sbjct: 664 GTLFIK---NAAPKDAGIYGCLASNSAGTDK-QNSTLRY-IEAPKLMVVQSELLVALGDI 718 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIA 182 V+EC G P P V W K L S ++D G L IQ+ + DAG Y C+A Sbjct: 719 TVMEC-KTSGIPPPQVKWFKGDLEL---RPSTFLIIDPLLGLLKIQETQDLDAGDYTCVA 774 Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242 N AG R + TL + P I P DV + GS+VT C V G P P + WRR Sbjct: 775 INEAG-RATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRL---D 830 Query: 243 NMPL-------GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PP 293 NMP+ + L G+L + N+ +D+G Y CEAEN G + + +TV P Sbjct: 831 NMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAP 890 Query: 294 SINLSPNSVNVESGNVARFTCT-ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352 I +SP+ NV G CT G P P W I M + T DG Sbjct: 891 LIGISPSVANVIEGQQLTLPCTLLAGNPIPERRW-------IKNSAMLLQNPYITVRSDG 943 Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412 L I D C A N AG++ + V P I +G + Sbjct: 944 --SLHIERVQLQDG-GEYTCVASNVAGTNNKTTSVVV-----HVLPTIQHGQQILSTIEG 995 Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKDLDKSDSGTYTCVASS 471 PC A P+P + W +GE + + + + DG+L + +SG Y C A++ Sbjct: 996 IPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 1055 Query: 472 RHG 474 G Sbjct: 1056 TAG 1058 Score = 160 bits (389), Expect = 2e-37 Identities = 135/481 (28%), Positives = 205/481 (42%), Gaps = 49/481 (10%) Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77 P ++ V R + +L C G P P + W K G ++ IL G + L+ H Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIH---V 2355 Query: 78 SDAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136 SD G Y C A N G T + + ++H PE+ + ++V L C G P Sbjct: 2356 SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTC-EASGIP 2414 Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196 P++ W K+G + R+ L G L + DAG+Y C+ RNAAG E I L Sbjct: 2415 LPSITWFKDGWPVSLSNSVRI-LSGGRMLRLMQTTMEDAGQYTCVVRNAAG-EERKIFGL 2472 Query: 197 KIHIKPYLI--TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254 + + P+++ EDV + SVT C V G+P+P++ W + + Sbjct: 2473 SVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGG 2532 Query: 255 GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-----NLSPNSVNVESGNV 309 L++ NV + G Y+C A + G S S L V+ P+I + +P V V + Sbjct: 2533 RFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSP 2592 Query: 310 ARFTCTATGRPEPTMFW-----SVEGNRTI-IFPGMSRDKYHATAVFDGVTVLTINDTDK 363 C A P T+ W +E NR I I PG G T+ +N + Sbjct: 2593 TSLVCEAYSYPPATITWFKDGTPLESNRNIRILPG-------------GRTLQILNAQED 2639 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--------PSNQTLPIKSMA 415 N R + C A N AG ++ V PPII G P + + + Sbjct: 2640 NAGRYS--CVATNEAGEMIKHYEVKVYI-----PPIINKGDLWGPGLSPKEVKIKVNNTL 2692 Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474 C A P ++WY +G+ L + N+ +G TL +K+ SD+G YTCVAS+ G Sbjct: 2693 TLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAG 2752 Query: 475 K 475 + Sbjct: 2753 E 2753 Score = 156 bits (379), Expect = 3e-36 Identities = 132/470 (28%), Positives = 209/470 (44%), Gaps = 33/470 (7%) Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77 P +VTV ++ A + C + GSP+P W K G ++ D H L G + + T Sbjct: 2879 PEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQ---I 2935 Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137 +D G Y C A N+ G+A+ + L+V V + E+ + + L C G P Sbjct: 2936 TDIGRYVCVAENTAGSAK-KYFNLNVHVPPSVIGPKSENLTVVVNNFISLTC-EVSGFPP 2993 Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196 P++ W KN Q + + ++ +V GG L I A+ +D G Y CIA N AG + +L Sbjct: 2994 PDLSWLKNEQPIKLNTNTL--IVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKF-SL 3050 Query: 197 KIHIKPYLITGPED----VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL 252 +++ P + + V + G+SV+ +C P P + W ++ G V++L Sbjct: 3051 TVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKN-GRMITESTHVEIL 3109 Query: 253 DDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES-GNVA 310 DG L + ++D G+Y C A N G + +L VY PPSI V VE+ N Sbjct: 3110 ADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPV 3169 Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370 TC ATG P PT+ W R + + G + L I + +DS N Sbjct: 3170 TLTCDATGIPPPTIAWLKNHKR------IENSDSLEVRILSGGSKLQIARSQHSDSGN-Y 3222 Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--PSNQTLPIKSMAVFPCTAICTPEPI 428 C A N G + L++ + PP + PS+ ++ + C A P P+ Sbjct: 3223 TCIASNMEGKAQKYYFLSI-----QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3277 Query: 429 IAWYFEGEALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 I W +G+ + + N TL + SD+G YTCVA++ G+ Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327 Score = 155 bits (377), Expect = 5e-36 Identities = 133/483 (27%), Positives = 202/483 (41%), Gaps = 35/483 (7%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRA-GGSPSPAIRWYKGGVLVVSDTHRSILPAG 64 VT AP I P V Q TL C G+P P RW K +++ + + ++ G Sbjct: 884 VTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG 943 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124 L R D G Y C A+N GT ++ ++ V VL + + + +G Sbjct: 944 SLHIERVQL----QDGGEYTCVASNVAGT-NNKTTSVVVHVL-PTIQHGQQILSTIEGIP 997 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 V L C G+P+P+V W K G+ L+ ++ G+L + ++G Y C A N Sbjct: 998 VTLPC-KASGNPKPSVIWSKKGE-LISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 1055 Query: 185 AAGTRESAIATLKIHIKPYLITG--------PEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 AG + + L ++++P + P ++ G VT C V P P + W Sbjct: 1056 TAGYAKRKVQ-LTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWA 1114 Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296 + + R L GS+++ +D G Y C A N G V+ + L V+ PP I Sbjct: 1115 KETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQ 1174 Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356 P + V+ G C A G P P + WS G+ ++ D H + DG L Sbjct: 1175 RGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLV------DGEHHVSNPDG--TL 1226 Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD---DDRPPPIITNGPSNQTLPIKS 413 +I+ +D+ C A N AG+ L V +D PP T + Q Sbjct: 1227 SIDQATPSDA-GIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNT---TFQERVANQ 1282 Query: 414 MAVFPCTAICTPEPIIAWYFEGEALI-QNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASS 471 FPC A TP+P I W G L + ++ DGT LV+ + D+G Y CVA + Sbjct: 1283 RIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVN 1342 Query: 472 RHG 474 G Sbjct: 1343 EAG 1345 Score = 155 bits (377), Expect = 5e-36 Identities = 138/469 (29%), Positives = 195/469 (41%), Gaps = 34/469 (7%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLFFLR 70 P I P + V Q + C A G+P P I W KGG ++V H P G L + Sbjct: 1171 PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQ 1230 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ----GDTVV 126 AT SDAG+Y C ATN GT + TLHV LEP + Q + Sbjct: 1231 ATP----SDAGIYTCVATNIAGTDETE-ITLHVQEPPTVEDLEPPYNTTFQERVANQRIE 1285 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186 C P +G+P+P + W NG+ L L DG LVI D G Y C+A N A Sbjct: 1286 FPC-PAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEA 1344 Query: 187 GTRESAIATLKIHIKPYLITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 GT E LK+H+ P + + +V C V G P P ++W + Sbjct: 1345 GTTERKY-NLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKD-NVQVT 1402 Query: 245 PLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNS 301 ++ +++G L+L D G YSC+A N G + V PP+I PN Sbjct: 1403 ESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNE 1462 Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361 V+V C G P P + W +G +F G + D VL + + Sbjct: 1463 VSVVLNRDVALECQVKGTPFPDIHWFKDGKP--LFLGDPN-----VELLDRGQVLHLKNA 1515 Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--PSNQTLPIKSMAVFPC 419 +ND + C+ N AG KLT+ PP I G ++ ++ I S+ C Sbjct: 1516 RRND-KGRYQCTVSNAAGKQAKDIKLTIYI-----PPSIKGGNVTTDISVLINSLIKLEC 1569 Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTC 467 P P I WY +G+ ++ + + + G L + SDS TYTC Sbjct: 1570 ETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTC 1618 Score = 154 bits (373), Expect = 2e-35 Identities = 130/464 (28%), Positives = 214/464 (46%), Gaps = 37/464 (7%) Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAG 81 V +++P L C A G P+P+I W K V + + I +G + + T + DAG Sbjct: 1838 VVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKT---LLEDAG 1894 Query: 82 VYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ----GDTVVLECLPPRGSPE 137 Y C ATN+ G + ++ LHV E LE K + + V LEC G+P Sbjct: 1895 RYTCVATNAAGETQ-QHIQLHV---HEPPSLEDAGKMLNETVLVSNPVQLEC-KAAGNPV 1949 Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATL 196 P + W K+ + L G + M ++ G ++ I+ A+ +DAG Y+C+A N+AG E +L Sbjct: 1950 PVITWYKDNR--LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATE-LFYSL 2006 Query: 197 KIHIKPYLITGPEDVVA-QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255 ++H+ P I+G ++VA + V +C G P P + W + + ++VL G Sbjct: 2007 QVHVAP-SISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGG 2065 Query: 256 S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314 L L + ++D G Y+C A N+ G L VY PP+I +V+V C Sbjct: 2066 RILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLC 2125 Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374 + P PT+ W +G+ + PG+S + + +VL I D D+ C A Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLS--------ISENRSVLKIEDAQVQDT-GRYTCEA 2176 Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK-SMAVFPCTAICTPEPIIAWYF 433 N AG + + + PP I + Q I+ ++ C + P P + W Sbjct: 2177 TNVAGKTEKNYNVNIWV----PPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKK 2232 Query: 434 EGEALIQNH--RRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474 +G ++ + R + + G L + +KSD+ Y+CVAS+ G Sbjct: 2233 KGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAG 2276 Score = 152 bits (369), Expect = 5e-35 Identities = 131/473 (27%), Positives = 207/473 (43%), Gaps = 31/473 (6%) Query: 10 EAPYI--IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGL 66 E P+I E+ +++V + P L C A G P+P + W K G L +D +++ GG Sbjct: 3525 EPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL---GGG 3581 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 LR + +V D G Y C A++ G + +HV EP + V Sbjct: 3582 EVLRISTAQVE-DTGRYTCLASSPAGDDDKEYLVRVHVPP-NIAGTDEPRDITVLRNRQV 3639 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARN 184 LEC P P + W +NG+ L R+ ++ GG L I +A D Y C+A N Sbjct: 3640 TLECKSD-AVPPPVITWLRNGERL--QATPRVRILSGGRYLQINNADLGDTANYTCVASN 3696 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG--GG 242 AG + + L +++ P + GP+ +V S +C G P P + WR+ G Sbjct: 3697 IAG-KTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAG 3755 Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302 N R +L++G L + + + D G Y C A N+ G L V+ PPSI P ++ Sbjct: 3756 NH--ARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNM 3813 Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362 V C ATG P+P++ W G+ ++ +++ Y + G V+ + Sbjct: 3814 TVIVNVQTTLACEATGIPKPSINWRKNGH--LLNVDQNQNSYRLLS--SGSLVII---SP 3866 Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422 D T C+ N AG LTV + PP I + P++ + + AV CTA Sbjct: 3867 SVDDTATYECTVTNGAGDDKRTVDLTV-----QVPPSIADEPTDFLVTKHAPAVITCTAS 3921 Query: 423 CTPEPIIAWYFEGEALI-QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 P P I W G L+ + + + G + + + +G YTCVA + G Sbjct: 3922 GVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAG 3974 Score = 151 bits (366), Expect = 1e-34 Identities = 138/476 (28%), Positives = 204/476 (42%), Gaps = 32/476 (6%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 AP I V V + P L C A G P+P++ W K G V S ++ + +GG L Sbjct: 2011 APSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGR-ILA 2069 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130 T ++ SD G Y C A N+ G + R+ L V V E ++ V L C Sbjct: 2070 LTSAQI-SDTGRYTCVAVNAAG-EKQRDIDLRVYV-PPNIMGEEQNVSVLISQAVELLC- 2125 Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190 P P + W K+G LL + + L I+DA+ D GRY C A N AG E Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLSIS-ENRSVLKIEDAQVQDTGRYTCEATNVAGKTE 2184 Query: 191 SAIATLKIHIKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGG-NMPL 246 + I + P I G +++ T G+ ++ C G P P+++W++ + Sbjct: 2185 KNY-NVNIWVPPN-IGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSM 2242 Query: 247 GRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS---PNSV 302 GRV++L G L++ +D YSC A N G L VY P+I S P + Sbjct: 2243 GRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEI 2302 Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362 V G C G P PT+ W +G+ I K + D +L + + Sbjct: 2303 IVTRGKSISLECEVQGIPPPTVTWMKDGHPLI--------KAKGVEILDEGHILQLKNIH 2354 Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN--GPSNQTLPIKSMAVFPCT 420 +D+ VC AVN AG + + L+V + PP II N P N ++ K+ C Sbjct: 2355 VSDT-GRYVCVAVNVAGMTDKKYDLSVHA----PPSIIGNHRSPENISVVEKNSVSLTCE 2409 Query: 421 AICTPEPIIAWYFEG-EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 A P P I W+ +G + N R ++ L L D+G YTCV + G+ Sbjct: 2410 ASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGE 2465 Score = 149 bits (362), Expect = 3e-34 Identities = 128/454 (28%), Positives = 194/454 (42%), Gaps = 34/454 (7%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 L+C GSP P I W K G L+ IL G + +V S+ G+Y C A N+ Sbjct: 1754 LDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVI--AQAQV-SNTGLYRCMAANT 1810 Query: 91 YGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149 G + T+HV + L + + V L+C+ G P P++ W K+ Q + Sbjct: 1811 AGDHKKEFEVTVHVPPTIKSSGLS--ERVVVKYKPVALQCIA-NGIPNPSITWLKDDQPV 1867 Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209 + G L I DAGRY C+A NAAG + I L +H P L + Sbjct: 1868 NTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQ-LHVHEPPSLEDAGK 1926 Query: 210 --DVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGGGNMP-LGRVKVLDDGSLRLDNV 262 + + V +C+ G+P+P + W R +G +M L R +++D +++ Sbjct: 1927 MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIID-----IESA 1981 Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEP 322 ++D G Y C A NS GA L V+ PSI+ S N V V N R C A G P P Sbjct: 1982 QISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAP 2041 Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382 ++ W +G+ F + V G +L + +D+ C AVN AG Sbjct: 2042 SLTWLKDGSPVSSFS-------NGLQVLSGGRILALTSAQISDT-GRYTCVAVNAAGEKQ 2093 Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH 442 L V PP I N ++ I C + P P + W +G L++ Sbjct: 2094 RDIDLRV-----YVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKP 2148 Query: 443 RRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGK 475 +++ N L ++D D+G YTC A++ GK Sbjct: 2149 GLSISENRSVLKIEDAQVQDTGRYTCEATNVAGK 2182 Score = 149 bits (361), Expect = 5e-34 Identities = 136/491 (27%), Positives = 206/491 (41%), Gaps = 33/491 (6%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 EAP ++ ++ VA + C+ G P P ++W+KG + + T I P GL + Sbjct: 700 EAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKI 759 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 + T DAG Y C A N G A + TL V F EP G V L C Sbjct: 760 QETQDL---DAGDYTCVAINEAGRATGK-ITLDVGS-PPVFIQEPADVSMEIGSNVTLPC 814 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGD---SRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186 +G PEP + W++ +F S + + G L I + +D G Y C A N Sbjct: 815 YV-QGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQF 873 Query: 187 GTRES-AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLW-RRSAGGGN 243 G +S T+ + P + P G +T C + G+P+P+ W + SA Sbjct: 874 GKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ 933 Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303 P + V DGSL ++ V L D GEY+C A N G + + + V+ P+I ++ Sbjct: 934 NPY--ITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILS 991 Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363 G C A+G P+P++ WS +G S K+ A A DG + + Sbjct: 992 TIEGIPVTLPCKASGNPKPSVIWSKKGE----LISTSSAKFSAGA--DGSLYVV---SPG 1042 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK------SMAVF 417 + VC+A N AG + + +LTV RP +Q P++ Sbjct: 1043 GEESGEYVCTATNTAGYAKRKVQLTVYV---RPRVFGDQRGLSQDKPVEISVLAGEEVTL 1099 Query: 418 PCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476 PC P PII W E + + + R G++ + + SDSG Y CVA++ G Sbjct: 1100 PCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNV 1159 Query: 477 VWSGALLVDSP 487 + L V P Sbjct: 1160 TQAVKLNVHVP 1170 Score = 149 bits (361), Expect = 5e-34 Identities = 121/466 (25%), Positives = 198/466 (42%), Gaps = 24/466 (5%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80 +TV +L C + G P P + W K G V++D+ + G L+ + SDA Sbjct: 2206 LTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAE-KSDA 2264 Query: 81 GVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139 +Y C A+N GTA+ N +++ P +G ++ LEC +G P P Sbjct: 2265 ALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLEC-EVQGIPPPT 2323 Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKI 198 V W K+G L+ + ++D G+++ +++ +D GRY C+A N AG + L + Sbjct: 2324 VTWMKDGHPLI--KAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKY-DLSV 2380 Query: 199 HIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255 H P +I PE++ +SV+ C G PLP + W + ++ V++L G Sbjct: 2381 HAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLS-NSVRILSGG 2439 Query: 256 S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNVESGNVARF 312 LRL + D G+Y+C N+ G L+V PP I + V V+ Sbjct: 2440 RMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTL 2499 Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372 TC TG P P + W +G P + +H + G L I + + C Sbjct: 2500 TCEVTGNPVPEITWHKDGQ-----PLQEDEAHH---IISGGRFLQITNVQVPHT-GRYTC 2550 Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432 A + AG L V P + T+ + S C A P I W+ Sbjct: 2551 LASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWF 2610 Query: 433 FEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKYV 477 +G L N + G TL + + + ++G Y+CVA++ G+ + Sbjct: 2611 KDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMI 2656 Score = 147 bits (355), Expect = 2e-33 Identities = 138/533 (25%), Positives = 230/533 (43%), Gaps = 34/533 (6%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFF 68 E P +I+ P +VTV + A L C + + W + V +++ R A Sbjct: 518 EPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLE 577 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVL 127 L++ +DAG Y C ++ G++ A++ + V + + P+++ G V + Sbjct: 578 LKSVK---FNDAGEYHCMVSSEGGSSA---ASVFLTVQEPPKVTVMPKNQSFTGGSEVSI 631 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 C G P+P + W N ++ G R + G L I++A DAG Y C+A N+AG Sbjct: 632 MC-SATGYPKPKIAWTVNDMFIV--GSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAG 688 Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247 T + +TL+ P L+ +++ G +C+ G P P V W + G + Sbjct: 689 T-DKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFK--GDLELRPS 745 Query: 248 RVKVLDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305 ++D G L++ D G+Y+C A N G + L V PP P V++E Sbjct: 746 TFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSME 805 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTII---FPGMSRDKYHATAVFDGVTVLTINDTD 362 G+ C G PEPT+ W N I F S + A+F +L + +D Sbjct: 806 IGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF----ILNLWASD 861 Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422 K T +C A N G ++ + TVT P+I PS + PCT + Sbjct: 862 K----GTYICEAENQFGK--IQSETTVTV-TGLVAPLIGISPSVANVIEGQQLTLPCTLL 914 Query: 423 C-TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481 P P W L+QN V +DG+L ++ + D G YTCVAS+ G + + Sbjct: 915 AGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTS 974 Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSS 534 ++V + P I + +S++ G P + ++ WS+ ++ S+S Sbjct: 975 VVVH--VLPTIQHGQQI-LSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTS 1024 Score = 140 bits (339), Expect = 2e-31 Identities = 126/466 (27%), Positives = 185/466 (39%), Gaps = 31/466 (6%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80 V V +L C + P P I WYK G ++ TH IL G + ++ SD Sbjct: 3069 VNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAE---VSDT 3125 Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140 G Y C A N G +N L+V V E E + V L C G P P + Sbjct: 3126 GQYVCRAINVAG-RDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTC-DATGIPPPTI 3183 Query: 141 YWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199 W KN + + + ++ GG+ L I ++ +D+G Y CIA N G + L I Sbjct: 3184 AWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEG-KAQKYYFLSIQ 3242 Query: 200 IKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDGS 256 + P + P DV G +V C G P P + W + + R++V +GS Sbjct: 3243 VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS 3302 Query: 257 -LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV---ARF 312 L + + +D G+Y+C A N G L VY P+I + + V Sbjct: 3303 TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINI 3362 Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372 C ATG P P + W G + P S + A + ++D C Sbjct: 3363 ECRATGTPPPQINWLKNG---LPLPLSSHIRLLAAGQVIRIVRAQVSDV------AVYTC 3413 Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEPIIA 430 A N AG L V + PP + N + + + S C TP P +A Sbjct: 3414 VASNRAGVDNKHYNLQVFA-----PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 3468 Query: 431 WYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 W +G+ L + H T+ L L + DSG YTC+AS+ G+ Sbjct: 3469 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGE 3514 Score = 128 bits (309), Expect = 9e-28 Identities = 128/486 (26%), Positives = 195/486 (40%), Gaps = 50/486 (10%) Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77 P +++V +L C A G P P+I W+K G V IL G + L T Sbjct: 2393 PENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQT---TM 2449 Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEPESKQSAQGDTVVLECLPPRG 134 DAG Y C N+ G R + L V V + E LE + Q T+ E G Sbjct: 2450 EDAGQYTCVVRNAAGEER-KIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVT---G 2505 Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAI 193 +P P + W K+GQ L D H++ GG L I + + GRY C+A + AG + + Sbjct: 2506 NPVPEITWHKDGQPL--QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2563 Query: 194 ATLKIHIKPYLIT-----GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248 + L + + P + PEDV S + C P + W + G + R Sbjct: 2564 S-LNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKD--GTPLESNR 2620 Query: 249 -VKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN--------LS 298 +++L G +L++ N + G YSC A N G + + VY PP IN LS Sbjct: 2621 NIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLS 2680 Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358 P V ++ N C A P ++ W +G P S D H +G T L I Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQ-----PLKSDD--HVNIAANGHT-LQI 2732 Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP--------PIITNGPSNQTLP 410 + +D+ C A N AG + + + NG + + Sbjct: 2733 KEAQISDT-GRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVII 2791 Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVA 469 ++++ C P P + WY +G L + + + G L + D+G YTCVA Sbjct: 2792 NNPISLY-CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVA 2850 Query: 470 SSRHGK 475 + G+ Sbjct: 2851 VNEAGE 2856 Score = 126 bits (304), Expect = 4e-27 Identities = 132/495 (26%), Positives = 209/495 (42%), Gaps = 54/495 (10%) Query: 12 PYII-EQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 P+I+ E L DV V Q TL C G+P P I W+K G + D I+ G FL Sbjct: 2478 PHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGR--FL 2535 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL----EPESKQSAQGDTV 125 + T+ +V G Y C A++ G +SR+ +L+V V + PE Sbjct: 2536 QITNVQV-PHTGRYTCLASSPAG-HKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPT 2593 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 L C P + W K+G L + + R+ L G L I +A++ +AGRY C+A N Sbjct: 2594 SLVC-EAYSYPPATITWFKDGTPLESNRNIRI-LPGGRTLQILNAQEDNAGRYSCVATNE 2651 Query: 186 AGTRESAIATLKIHIKPYLITG--------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 AG +K++I P + G P++V + +++T +C P + W + Sbjct: 2652 AGEMIKHY-EVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYK 2710 Query: 238 SAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI- 295 G V + +G +L++ ++D G Y+C A N G + + PPS Sbjct: 2711 D-GQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQ 2769 Query: 296 ------NLSPNSVNVES-----GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344 N+ N E+ N C P PT+ W +G+ P S DK Sbjct: 2770 KLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGH-----PLTSSDK- 2823 Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG- 403 + G VL I D+ C AVN AG ++ + V PPII Sbjct: 2824 --VLILPGGRVLQIPRAKVEDA-GRYTCVAVNEAGEDSLQYDVRVL-----VPPIIKGAN 2875 Query: 404 ---PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDLDK 459 P T+ + A+ C + +P P +W +G+ L++ +H + ++N L + + Sbjct: 2876 SDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQI 2935 Query: 460 SDSGTYTCVASSRHG 474 +D G Y CVA + G Sbjct: 2936 TDIGRYVCVAENTAG 2950 Score = 123 bits (296), Expect = 3e-26 Identities = 107/421 (25%), Positives = 180/421 (42%), Gaps = 26/421 (6%) Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137 SD G Y C A +S GT R++ V+ ++ P + G+ VL CL + + Sbjct: 492 SDEGFYECIAVSSAGTGRAQ-TFFDVSEPPPVIQV-PNNVTVTPGERAVLTCL-IISAVD 548 Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197 N+ W++N + + +R+ + +L ++ + DAG Y C+ + G+ +A L Sbjct: 549 YNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGS-SAASVFLT 607 Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257 + P + P++ GS V+ C G P P + W + + R ++ DG+L Sbjct: 608 VQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVN-DMFIVGSHRYRMTSDGTL 666 Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317 + N D G Y C A NS G + L + P + + + + V G++ C + Sbjct: 667 FIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTS 726 Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT-VLTINDTDKNDSRNTIVCSAVN 376 G P P + W F G + + D + +L I +T D+ C A+N Sbjct: 727 GIPPPQVKW---------FKGDLELRPSTFLIIDPLLGLLKIQETQDLDA-GDYTCVAIN 776 Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436 AG + GK+T+ D PP+ P++ ++ I S PC PEP I W Sbjct: 777 EAGRA--TGKITL---DVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDN 831 Query: 437 ALIQNHRRNVTN-----DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPN 491 I + +V++ G L + +L SD GTY C A ++ GK + V + P Sbjct: 832 MPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPL 891 Query: 492 I 492 I Sbjct: 892 I 892 Score = 103 bits (246), Expect = 4e-20 Identities = 88/327 (26%), Positives = 144/327 (44%), Gaps = 20/327 (6%) Query: 164 NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223 NL I +D G Y+CIA ++AGT A + P +I P +V G C Sbjct: 483 NLDIAKVTLSDEGFYECIAVSSAGTGR-AQTFFDVSEPPPVIQVPNNVTVTPGERAVLTC 541 Query: 224 RVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVS 282 + ++ W+R+ + R++ L + SL L +V D GEY C + G+ + Sbjct: 542 LIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSA 601 Query: 283 ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRD 342 AS +LTV +PP + + P + + G+ C+ATG P+P + W+V N I + Sbjct: 602 ASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTV--NDMFI---VGSH 656 Query: 343 KYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN 402 +Y T+ DG L I + D+ C A N AG+ L + P ++ Sbjct: 657 RYRMTS--DG--TLFIKNAAPKDA-GIYGCLASNSAGTDKQNSTLRYI---EAPKLMVVQ 708 Query: 403 GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND--GTLVLKDLDKS 460 S + + + V C P P + W F+G+ ++ + + G L +++ Sbjct: 709 --SELLVALGDITVMECKTSGIPPPQVKW-FKGDLELRPSTFLIIDPLLGLLKIQETQDL 765 Query: 461 DSGTYTCVASSRHGKYVWSGALLVDSP 487 D+G YTCVA + G+ L V SP Sbjct: 766 DAGDYTCVAINEAGRATGKITLDVGSP 792 Score = 38.7 bits (86), Expect = 0.96 Identities = 24/92 (26%), Positives = 37/92 (40%), Gaps = 4/92 (4%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 +T P I +P++ + LNC+A G P P I W + G + D ++L Sbjct: 4434 LTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNS 4493 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97 L+ A D + C A N G+ R Sbjct: 4494 LYIADAQ----KEDTSEFECVARNLMGSVLVR 4521 >UniRef50_Q4RJ20 Cluster: Chromosome 1 SCAF15039, whole genome shotgun sequence; n=4; Eumetazoa|Rep: Chromosome 1 SCAF15039, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 3493 Score = 204 bits (499), Expect = 9e-51 Identities = 146/464 (31%), Positives = 208/464 (44%), Gaps = 26/464 (5%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFFLR 70 P+I ++P ++ V R P + C A G P P ++W K GV + ++ SILP+G L Sbjct: 1877 PFIADEPTEMVVTRLSPVVMGCSASGVPEPTVQWSKDGVALPNEERGYSILPSGPLEITS 1936 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130 A S G Y C A N+ G+ R+ L V + +P + + V L C Sbjct: 1937 AEL----SHTGRYTCTAENAAGSTH-RHVQLTVQEV-PVIASQPSTLDVILKNPVTLPCR 1990 Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190 GSP P + W+K G ++ G S ++ G+L I +D+G Y C+A+N AGT Sbjct: 1991 AT-GSPRPTISWQKEGMSISTTGGS-FTVLPNGSLRISTTSVSDSGTYMCVAQNPAGTAL 2048 Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250 I LK+ + P + + A T SSVT QC V G P P V W + G R + Sbjct: 2049 GKIK-LKVQVPPVIGSDTRTYRAPTDSSVTLQCHVDGSPPPSVTWNKD-GQPLAESVRRR 2106 Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310 VL GSL+L V D G Y+C A N G VS LTV PPSI V V + Sbjct: 2107 VLSSGSLQLAFVQSEDTGRYTCTAANPAGTVSLEMSLTVQVPPSIRGGEKEVAVVENSRV 2166 Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370 + C A G P+PT+ W +GN +F S T + G ++T + + Sbjct: 2167 QLVCVAEGVPQPTLSWEKDGN---LF---SESSEEPTVLPSGELIIT---RAQAEDAGRY 2217 Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA 430 C A N G L+V + P+ T + L + C P P I Sbjct: 2218 TCVATNELGQDRWTATLSVQTH-----PVFTELLGDVALKKGERLLLACGVNGIPTPHIT 2272 Query: 431 WYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 W F +++ H + LV++ + K DSGTYTCVA +R G Sbjct: 2273 WVF-NNSILPVHYDHANGHSQLVIERVTKEDSGTYTCVAENRVG 2315 Score = 198 bits (484), Expect = 6e-49 Identities = 155/526 (29%), Positives = 232/526 (44%), Gaps = 27/526 (5%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 AP I E V+ ++ A L C G P P + W K G ++ + R G L Sbjct: 1692 APSIEEGSQAVSAPVNKSAVLECVVNGVPPPQVTWRKHGAILAGNNPRYRFAEDGS--LH 1749 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 T +V SD G Y C ATN G R R + ++V E RL+ + + Q L C Sbjct: 1750 ITSAQV-SDTGRYLCMATNQAGIQRRRVDLQVYVPPSISEGRLDVKVTVNVQ---TALSC 1805 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMH-LVDGGNLVIQDARQTDAGRYQCIARNAAGT 188 G P P V W KNG+ + D + M+ L+ G+LV+ D Y+C+ N AG Sbjct: 1806 -EASGIPRPTVTWMKNGRVINTDQNQNMYRLLTSGSLVVIAPTVEDTAVYECVVSNEAGV 1864 Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248 S L +H+ P++ P ++V S V C G P P V W + Sbjct: 1865 A-SRFINLTVHVPPFIADEPTEMVVTRLSPVVMGCSASGVPEPTVQWSKDGVALPNEERG 1923 Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGN 308 +L G L + + L+ G Y+C AEN+ G+ LTV + P I P++++V N Sbjct: 1924 YSILPSGPLEITSAELSHTGRYTCTAENAAGSTHRHVQLTVQEVPVIASQPSTLDVILKN 1983 Query: 309 VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368 C ATG P PT+ W EG +I G S T + +G L I+ T +DS Sbjct: 1984 PVTLPCRATGSPRPTISWQKEG-MSISTTGGS-----FTVLPNGS--LRISTTSVSDS-G 2034 Query: 369 TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428 T +C A N AG++ + KL V + PP+I + P S C +P P Sbjct: 2035 TYMCVAQNPAGTALGKIKLKV-----QVPPVIGSDTRTYRAPTDSSVTLQCHVDGSPPPS 2089 Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPI 488 + W +G+ L ++ RR V + G+L L + D+G YTC A++ G +L V P Sbjct: 2090 VTWNKDGQPLAESVRRRVLSSGSLQLAFVQSEDTGRYTCTAANPAGTVSLEMSLTVQVP- 2148 Query: 489 NPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSS 534 P+I +V+ + + + TLSW ++ + S S Sbjct: 2149 -PSIR-GGEKEVAVVENSRVQLVCVAEGVPQPTLSWEKDGNLFSES 2192 Score = 178 bits (434), Expect = 7e-43 Identities = 133/480 (27%), Positives = 203/480 (42%), Gaps = 30/480 (6%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRS---ILPAGGLFF 68 P I E LDV V + L+C A G P P + W K G ++ +D +++ +L +G L Sbjct: 1784 PSISEGRLDVKVTVNVQTALSCEASGIPRPTVTWMKNGRVINTDQNQNMYRLLTSGSLVV 1843 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127 + T D VY C +N G A R N T+HV + EP + VV+ Sbjct: 1844 IAPTV----EDTAVYECVVSNEAGVASRFINLTVHVPPFIAD---EPTEMVVTRLSPVVM 1896 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 C G PEP V W K+G L + + ++ G L I A + GRY C A NAAG Sbjct: 1897 GC-SASGVPEPTVQWSKDGVALPNE-ERGYSILPSGPLEITSAELSHTGRYTCTAENAAG 1954 Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247 + + L + P + + P + + VT CR G P P + W++ + G Sbjct: 1955 STHRHVQ-LTVQEVPVIASQPSTLDVILKNPVTLPCRATGSPRPTISWQKEGMSISTTGG 2013 Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESG 307 VL +GSLR+ ++D G Y C A+N G L V PP I + + Sbjct: 2014 SFTVLPNGSLRISTTSVSDSGTYMCVAQNPAGTALGKIKLKVQVPPVIGSDTRTYRAPTD 2073 Query: 308 NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367 + C G P P++ W+ +G + + G L ++ + R Sbjct: 2074 SSVTLQCHVDGSPPPSVTWNKDGQPLA-------ESVRRRVLSSGSLQLAFVQSE-DTGR 2125 Query: 368 NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427 T C+A N AG+ + LTV + PP I G + S C A P+P Sbjct: 2126 YT--CTAANPAGTVSLEMSLTV-----QVPPSIRGGEKEVAVVENSRVQLVCVAEGVPQP 2178 Query: 428 IIAWYFEGEALIQNHRR-NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486 ++W +G ++ V G L++ D+G YTCVA++ G+ W+ L V + Sbjct: 2179 TLSWEKDGNLFSESSEEPTVLPSGELIITRAQAEDAGRYTCVATNELGQDRWTATLSVQT 2238 Score = 172 bits (418), Expect = 6e-41 Identities = 127/446 (28%), Positives = 190/446 (42%), Gaps = 27/446 (6%) Query: 30 TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89 TL C GSP P++ W K G + R +L +G L D G Y C A N Sbjct: 2077 TLQCHVDGSPPPSVTWNKDGQPLAESVRRRVLSSGSLQLAFVQS----EDTGRYTCTAAN 2132 Query: 90 SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149 GT S +L V V R + + V L C+ G P+P + W+K+G L Sbjct: 2133 PAGTV-SLEMSLTVQV-PPSIRGGEKEVAVVENSRVQLVCVA-EGVPQPTLSWEKDGN-L 2188 Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209 + ++ G L+I A+ DAGRY C+A N G ++ ATL + P Sbjct: 2189 FSESSEEPTVLPSGELIITRAQAEDAGRYTCVATNELG-QDRWTATLSVQTHPVFTELLG 2247 Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGE 269 DV + G + C V G P P + W +P+ L ++ V D G Sbjct: 2248 DVALKKGERLLLACGVNGIPTPHITW--VFNNSILPVHYDHANGHSQLVIERVTKEDSGT 2305 Query: 270 YSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES-GNVARFTCTATGRPEPTMFWSV 328 Y+C AEN VG + + G++++ +PP I+ S +E G A C G P PT+ WS Sbjct: 2306 YTCVAENRVGTIKSLGFVSILEPPIIDGDLRSNRIEPLGGNAVLNCEVRGDPPPTIRWSK 2365 Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT 388 G I + + + A++ V+ + + C A N AG+ V +T Sbjct: 2366 NGIHITIGDRIRQLNNGSLAIYGTVS----------EDAGSYTCVATNDAGA--VERSVT 2413 Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN 448 +T + P IT P + S V C A P P I W +G L+ N R + + Sbjct: 2414 LTL---QRAPTITEEPVGTVVDAGSTVVLNCQAEGEPTPTIEWSQQGRPLLGNDRFSSLS 2470 Query: 449 DGTLVLKDLDKSDSGTYTCVASSRHG 474 +G+L + + K D+ Y CVA + G Sbjct: 2471 NGSLRISSVQKEDTARYECVARNLVG 2496 Score = 171 bits (416), Expect = 1e-40 Identities = 143/471 (30%), Positives = 200/471 (42%), Gaps = 28/471 (5%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRS--ILPA 63 +T E P I QP + V P TL CRA GSP P I W K G + +S T S +LP Sbjct: 1962 LTVQEVPVIASQPSTLDVILKNPVTLPCRATGSPRPTISWQKEG-MSISTTGGSFTVLPN 2020 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123 G LR + V SD+G Y C A N GTA + L V V + + ++ Sbjct: 2021 GS---LRISTTSV-SDSGTYMCVAQNPAGTALGK-IKLKVQV-PPVIGSDTRTYRAPTDS 2074 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183 +V L+C GSP P+V W K+GQ L R ++ G+L + + D GRY C A Sbjct: 2075 SVTLQC-HVDGSPPPSVTWNKDGQPLA--ESVRRRVLSSGSLQLAFVQSEDTGRYTCTAA 2131 Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 N AGT S +L + + P + G ++V S V C G P P + W + + Sbjct: 2132 NPAGT-VSLEMSLTVQVPPSIRGGEKEVAVVENSRVQLVCVAEGVPQPTLSWEKDGNLFS 2190 Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303 VL G L + D G Y+C A N +G + L+V P V Sbjct: 2191 ESSEEPTVLPSGELIITRAQAEDAGRYTCVATNELGQDRWTATLSVQTHPVFTELLGDVA 2250 Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363 ++ G C G P P + W N +I+ H+ V + VT K Sbjct: 2251 LKKGERLLLACGVNGIPTPHITWVF--NNSILPVHYDHANGHSQLVIERVT--------K 2300 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423 DS T C A N G+ G +++ PP I + SN+ P+ AV C Sbjct: 2301 EDS-GTYTCVAENRVGTIKSLGFVSIL----EPPIIDGDLRSNRIEPLGGNAVLNCEVRG 2355 Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 P P I W G + R N+G+L + D+G+YTCVA++ G Sbjct: 2356 DPPPTIRWSKNGIHITIGDRIRQLNNGSLAIYGTVSEDAGSYTCVATNDAG 2406 Score = 170 bits (413), Expect = 2e-40 Identities = 144/481 (29%), Positives = 212/481 (44%), Gaps = 43/481 (8%) Query: 17 QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV 76 +P +V V + TL C A PSPA++WYK G ++ D H SI +G + ++ H RV Sbjct: 607 KPKEVKVKVNSSLTLECAAQAFPSPALQWYKDGQILQVDDHMSITASGRM--VQVEHARV 664 Query: 77 HSDAGVYWCEATNSYGTARSR---NATLHVAVLREEFRLEPESKQSAQGDT--VVLE--- 128 SD G Y C ATN G N + R S +GD V+L Sbjct: 665 -SDTGRYTCVATNIAGEDEKDFDVNVQVPPNFTRAGGAAGSTSSPGVEGDVRDVILNNPI 723 Query: 129 --CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186 P P + W K+GQ LL GD + L G L I A+ DAGRY C+A N A Sbjct: 724 SLYCETNAVPPPTLTWYKDGQ-LLASGDKVLILPGGRVLQIPRAQAEDAGRYICMAVNEA 782 Query: 187 GTRESAIATLKIHIKPYLITG-----PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241 G +S +++ + P +I G PE+V + +C G+P P V W + + Sbjct: 783 G-EDSIHYDVRVLLPP-IIRGTVSDFPEEVTVLVNKTTQLECHADGNPAPRVSWFQDSQP 840 Query: 242 GNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS-INLSP 299 P GR ++L +G L++ ++D G Y C A N G+ S L V+ PP I +P Sbjct: 841 VR-PDGRHRILSNGRILQVLTAQVSDTGRYVCVAANVAGSAEKSFNLNVHVPPMVIGSNP 899 Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359 SVNV + +C ATG P PT+ W + G + HA + G L I Sbjct: 900 ESVNVVVNSFVSLSCEATGLPPPTLTWLND-------RGPVQANTHA-LIMPGGRTLQIM 951 Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA---- 415 +D C A+N AG + LTV PP I + + + ++A Sbjct: 952 KAKVSDG-GKYSCVAMNAAGEAHRHIYLTVFI-----PPSIRGSSGDSPVVVNTLAGKAS 1005 Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHG 474 C P P I+WY G + ++ + +G ++ +K SD+G Y C A++ G Sbjct: 1006 TLECETSAVPAPSISWYKNGRVVTESANLRILKEGQMLEIKTTGVSDTGQYVCKATNIAG 1065 Query: 475 K 475 + Sbjct: 1066 Q 1066 Score = 156 bits (378), Expect = 4e-36 Identities = 138/475 (29%), Positives = 209/475 (44%), Gaps = 33/475 (6%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I + L+ TV P L+C++ P P + W K G + ++L G + LR Sbjct: 3 PNIQGEELNATVMLGGPVVLHCQSDAIPPPTLSWRKDGRPLFRKPGLTVLSDGSV--LRV 60 Query: 72 THGRVHSDAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130 +V D+G Y CEATN G T ++ N + VA EP +G+ + + C Sbjct: 61 DSAQV-QDSGRYSCEATNVAGKTEKNYNLNVWVAPSIRGSE-EPTPLTVIEGNPITMVC- 117 Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTR 189 G P P++ W+K+G L R+ ++ GG L I A +TD Y C A +A+G Sbjct: 118 ESSGIPPPSLVWRKDGSEL--KPTQRLRVLSGGRQLQISSAARTDTASYSCTASSASGI- 174 Query: 190 ESAIATLKIHIKP--YLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 S +L+++++P L G D VA T G VT QC G P P V W + G Sbjct: 175 TSKEYSLQVYVRPSIKLSEGLSDDVAVTKGGDVTLQCAAEGIPRPAVTWLKD-GRPVSGQ 233 Query: 247 GRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS---PNSV 302 R KVL++G L++ V ++D G Y+C A N+ G + ++V+ PP I P +V Sbjct: 234 HRAKVLNEGRLLQIKTVKVSDTGRYTCVAVNAAGQADSRHDVSVHVPPVITGQVDVPENV 293 Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362 +V N +C A+G P P + W +G P + H V G L + Sbjct: 294 SVVLKNPVALSCEASGIPLPAISWLKDGQ-----PVRASSSVH---VLSGGRSLRLMHAA 345 Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT-LPIKSMAVFPCTA 421 D C N AG L + PP I G T + K C Sbjct: 346 VGDG-GRYTCVVSNMAGEERKNFDLDILV----PPSIEEEGTVVDTKVKEKHNLTLTCEV 400 Query: 422 ICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGK 475 P P I W +G+ L+ + V ++G L + +D+G Y+C+AS+ G+ Sbjct: 401 SGNPVPGIKWLKDGQMLVSDRHHQVFSNGRFLQIFGTRVADTGRYSCLASNSAGE 455 Score = 155 bits (375), Expect = 9e-36 Identities = 136/462 (29%), Positives = 195/462 (42%), Gaps = 33/462 (7%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 +V+V + L C A G P+P++ W K G ++D R +L G + LR ++ D Sbjct: 1519 EVSVIVNNDLELQCEASGVPAPSLTWLKDG-RPLADGLR-VLQGGEV--LRVASAQLE-D 1573 Query: 80 AGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138 G Y C A + G + +HV + E + V LEC P P Sbjct: 1574 TGRYSCLANSPAGDDDKEFLVRVHVPP-NIAGKSETQDVSVLLNRPVTLECKSD-AVPPP 1631 Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG--TRESAIATL 196 + W K+G+ L R+ L G L I A D +Y C A N AG TR +A Sbjct: 1632 TLTWLKDGRPLQASARVRI-LSRGSYLQINQAELDDRAQYTCEASNIAGQTTRHFNVA-- 1688 Query: 197 KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG--GGNMPLGRVKVLDD 254 +H+ P + G + V A S +C V G P P V WR+ GN P R + +D Sbjct: 1689 -VHVAPSIEEGSQAVSAPVNKSAVLECVVNGVPPPQVTWRKHGAILAGNNP--RYRFAED 1745 Query: 255 GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314 GSL + + ++D G Y C A N G L VY PPSI+ V V +C Sbjct: 1746 GSLHITSAQVSDTGRYLCMATNQAGIQRRRVDLQVYVPPSISEGRLDVKVTVNVQTALSC 1805 Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL-TINDTDKNDSRNTIVCS 373 A+G P PT+ W G +I +++ Y V + T+ DT + C Sbjct: 1806 EASGIPRPTVTWMKNGR--VINTDQNQNMYRLLTSGSLVVIAPTVEDTAVYE------CV 1857 Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF 433 N AG + LTV PP I + P+ + S V C+A PEP + W Sbjct: 1858 VSNEAGVASRFINLTV-----HVPPFIADEPTEMVVTRLSPVVMGCSASGVPEPTVQWSK 1912 Query: 434 EGEALIQNHR-RNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 +G AL R ++ G L + + S +G YTC A + G Sbjct: 1913 DGVALPNEERGYSILPSGPLEITSAELSHTGRYTCTAENAAG 1954 Score = 153 bits (370), Expect = 4e-35 Identities = 132/471 (28%), Positives = 198/471 (42%), Gaps = 34/471 (7%) Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGLFFLRATH 73 E P ++ V ++ L C+A G+P+P I+W K G V + I P G + H Sbjct: 1233 ELPREMGVLLNESIQLVCQASGTPTPTIQWLKDGEAVNHTGSSELRISPDGTTLTVFGAH 1292 Query: 74 GRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP 132 +D G Y C ATN+ G R N ++ + E + + +V LEC+ Sbjct: 1293 A---TDGGTYACVATNAAGEEDRIFNLNVYAPPVINGDSETVEERTAVLDASVSLECVAT 1349 Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192 GSP P + W +NG L R+ L G L I ++ +D+G Y CIA N AG +S Sbjct: 1350 -GSPPPQLNWLRNGLPLPLSSHVRL-LSAGQVLRITRSQVSDSGAYSCIASNRAGV-DSR 1406 Query: 193 IATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250 L++H+ P L EDV G+ V+ C G P P V W + G P ++ Sbjct: 1407 HYNLQVHVPPGLDGAGSTEDVTVVGGNMVSLLCVADGTPTPTVSWLKE-GSALFPASNLR 1465 Query: 251 VLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVNVESG 307 L+ + S+++ + + G YSC A+N+ G S L V DPP IN S V+V Sbjct: 1466 FLNLNMSMQIPQAHVNNTGRYSCVAKNTAGQASRHFNLKVLDPPRINGSDVVTEVSVIVN 1525 Query: 308 NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367 N C A+G P P++ W +G R V G VL + D+ Sbjct: 1526 NDLELQCEASGVPAPSLTWLKDG----------RPLADGLRVLQGGEVLRVASAQLEDT- 1574 Query: 368 NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTP 425 C A + AG + V PP I Q + + C + P Sbjct: 1575 GRYSCLANSPAGDDDKEFLVRV-----HVPPNIAGKSETQDVSVLLNRPVTLECKSDAVP 1629 Query: 426 EPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGK 475 P + W +G L + R + + G+ L + + D YTC AS+ G+ Sbjct: 1630 PPTLTWLKDGRPLQASARVRILSRGSYLQINQAELDDRAQYTCEASNIAGQ 1680 Score = 150 bits (363), Expect = 3e-34 Identities = 118/374 (31%), Positives = 171/374 (45%), Gaps = 28/374 (7%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFFLRATHGRVHS 78 +V V + L C A G P P + W K G L + ++LP+G L RA Sbjct: 2157 EVAVVENSRVQLVCVAEGVPQPTLSWEKDGNLFSESSEEPTVLPSGELIITRAQA----E 2212 Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138 DAG Y C ATN G R ATL V F +G+ ++L C G P P Sbjct: 2213 DAGRYTCVATNELGQDRW-TATLSVQT-HPVFTELLGDVALKKGERLLLAC-GVNGIPTP 2269 Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198 ++ W N L D H LVI+ + D+G Y C+A N GT +S + + I Sbjct: 2270 HITWVFNNSILPVHYD---HANGHSQLVIERVTKEDSGTYTCVAENRVGTIKS-LGFVSI 2325 Query: 199 HIKPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDG 255 ++P +I G + + G + C V GDP P + W S G ++ +G R++ L++G Sbjct: 2326 -LEPPIIDGDLRSNRIEPLGGNAVLNCEVRGDPPPTIRW--SKNGIHITIGDRIRQLNNG 2382 Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315 SL + + D G Y+C A N GAV S LT+ P+I P V++G+ C Sbjct: 2383 SLAIYGTVSEDAGSYTCVATNDAGAVERSVTLTLQRAPTITEEPVGTVVDAGSTVVLNCQ 2442 Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375 A G P PT+ WS +G P + D++ +++ +G L I+ K D+ C A Sbjct: 2443 AEGEPTPTIEWSQQGR-----PLLGNDRF--SSLSNG--SLRISSVQKEDTAR-YECVAR 2492 Query: 376 NYAGSSFVRGKLTV 389 N GS R LTV Sbjct: 2493 NLVGSVLARVPLTV 2506 Score = 141 bits (341), Expect = 1e-31 Identities = 132/463 (28%), Positives = 199/463 (42%), Gaps = 32/463 (6%) Query: 78 SDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136 SD+G Y C A+N G A +S T+ V L P +++ L C G+P Sbjct: 1199 SDSGTYTCVASNVEGRAHKSYRLTIRVPPRISGSEL-PREMGVLLNESIQLVC-QASGTP 1256 Query: 137 EPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195 P + W K+G+ + G S + + DG L + A TD G Y C+A NAAG E I Sbjct: 1257 TPTIQWLKDGEAVNHTGSSELRISPDGTTLTVFGAHATDGGTYACVATNAAG-EEDRIFN 1315 Query: 196 LKIHIKPYLITGPEDVVAQTG---SSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKV 251 L ++ P + E V +T +SV+ +C G P P + W R+ G +PL V++ Sbjct: 1316 LNVYAPPVINGDSETVEERTAVLDASVSLECVATGSPPPQLNWLRN--GLPLPLSSHVRL 1373 Query: 252 LDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL--SPNSVNVESGN 308 L G LR+ ++D G YSC A N G S L V+ PP ++ S V V GN Sbjct: 1374 LSAGQVLRITRSQVSDSGAYSCIASNRAGVDSRHYNLQVHVPPGLDGAGSTEDVTVVGGN 1433 Query: 309 VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368 + C A G P PT+ W EG + +FP S ++ + + +N+T + Sbjct: 1434 MVSLLCVADGTPTPTVSWLKEG--SALFPA-SNLRFLNLNMSMQIPQAHVNNTGRYS--- 1487 Query: 369 TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIKSMAVFPCTAICTPEP 427 C A N AG + L V PP I ++ + ++ + + C A P P Sbjct: 1488 ---CVAKNTAGQASRHFNLKVLD----PPRINGSDVVTEVSVIVNNDLELQCEASGVPAP 1540 Query: 428 IIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 + W +G L R + L + D+G Y+C+A+S G LV Sbjct: 1541 SLTWLKDGRPLADG-LRVLQGGEVLRVASAQLEDTGRYSCLANSPAGDD--DKEFLVRVH 1597 Query: 488 INPNI-HFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529 + PNI DVS L P + TL+W ++ + Sbjct: 1598 VPPNIAGKSETQDVSVLLNRPVTLECKSDAVPPPTLTWLKDGR 1640 Score = 138 bits (335), Expect = 6e-31 Identities = 125/437 (28%), Positives = 189/437 (43%), Gaps = 39/437 (8%) Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75 E+P +TV P T+ C + G P P++ W K G + T R + +GG ++ R Sbjct: 100 EEPTPLTVIEGNPITMVCESSGIPPPSLVWRKDG-SELKPTQRLRVLSGGRQLQISSAAR 158 Query: 76 VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE---PESKQSAQGDTVVLECLPP 132 +D Y C A+++ G S+ +L V V R +L + +G V L+C Sbjct: 159 --TDTASYSCTASSASGIT-SKEYSLQVYV-RPSIKLSEGLSDDVAVTKGGDVTLQC-AA 213 Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRES 191 G P P V W K+G+ + G R +++ G L+ I+ + +D GRY C+A NAAG +S Sbjct: 214 EGIPRPAVTWLKDGRPV--SGQHRAKVLNEGRLLQIKTVKVSDTGRYTCVAVNAAGQADS 271 Query: 192 AIATLKIHIKPYLITG----PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247 + +H+ P +ITG PE+V + V C G PLP + W + G Sbjct: 272 R-HDVSVHVPP-VITGQVDVPENVSVVLKNPVALSCEASGIPLPAISWLKD-GQPVRASS 328 Query: 248 RVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN--V 304 V VL G SLRL + + D G Y+C N G + L + PPSI V+ V Sbjct: 329 SVHVLSGGRSLRLMHAAVGDGGRYTCVVSNMAGEERKNFDLDILVPPSIEEEGTVVDTKV 388 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 + + TC +G P P + W +G + D++H VF L I T Sbjct: 389 KEKHNLTLTCEVSGNPVPGIKWLKDGQMLV------SDRHH--QVFSNGRFLQIFGTRVA 440 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424 D+ C A N AG L V P I +GP + A P + +C Sbjct: 441 DT-GRYSCLASNSAGERSRHYNLNVLVS----PTIAGSGPEGSVEEVTVTASSPTSLLCD 495 Query: 425 ----PEPIIAWYFEGEA 437 P ++ W +G + Sbjct: 496 AQSYPPAVVTWLRDGSS 512 Score = 134 bits (323), Expect = 2e-29 Identities = 145/519 (27%), Positives = 212/519 (40%), Gaps = 77/519 (14%) Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77 P +VTV ++ L C A G+P+P + W++ V D IL G + L+ +V Sbjct: 807 PEEVTVLVNKTTQLECHADGNPAPRVSWFQDSQPVRPDGRHRILSNGRI--LQVLTAQV- 863 Query: 78 SDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136 SD G Y C A N G+A +S N +HV + PES V L C G P Sbjct: 864 SDTGRYVCVAANVAGSAEKSFNLNVHVPPM--VIGSNPESVNVVVNSFVSLSC-EATGLP 920 Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIAT 195 P + W + + ++ ++ GG L I A+ +D G+Y C+A NAAG I Sbjct: 921 PPTLTWLNDRGPV--QANTHALIMPGGRTLQIMKAKVSDGGKYSCVAMNAAGEAHRHIY- 977 Query: 196 LKIHIKPYL--ITGPEDVVAQT--GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251 L + I P + +G VV T G + T +C P P + W ++ G +++ Sbjct: 978 LTVFIPPSIRGSSGDSPVVVNTLAGKASTLECETSAVPAPSISWYKN-GRVVTESANLRI 1036 Query: 252 LDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD------------------- 291 L +G L + ++D G+Y C+A N G V + +L VY Sbjct: 1037 LKEGQMLEIKTTGVSDTGQYVCKATNIAGQVDKNFHLNVYGRARLSVFTHESSCICATMP 1096 Query: 292 ------PPSINLSPNSVNVES-GNVARFTCTATGRPEPTMFWSVEGNRT--IIFPGMSR- 341 PP I E+ GN F C ATG P P + W G FP SR Sbjct: 1097 SQFSAVPPRIEGPAEEDIAETLGNPVSFACDATGIPPPALAWLKNGRPIGGAAFPSFSRL 1156 Query: 342 --DKYHATA------------------VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381 +K A +F G L I + +DS T C A N G + Sbjct: 1157 EMEKCVPLAFTCPCELFSENSESLEMHIFSGGGKLQIARSQVSDS-GTYTCVASNVEGRA 1215 Query: 382 FVRGKLTVTSDDDRPPPIITNG--PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL- 438 +LT+ R PP I+ P + + C A TP P I W +GEA+ Sbjct: 1216 HKSYRLTI-----RVPPRISGSELPREMGVLLNESIQLVCQASGTPTPTIQWLKDGEAVN 1270 Query: 439 -IQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGK 475 + ++ DG TL + +D GTY CVA++ G+ Sbjct: 1271 HTGSSELRISPDGTTLTVFGAHATDGGTYACVATNAAGE 1309 Score = 109 bits (263), Expect = 3e-22 Identities = 136/525 (25%), Positives = 210/525 (40%), Gaps = 85/525 (16%) Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75 + P+ V + +TL C P+P+I WYK G +V + IL G + ++ T Sbjct: 992 DSPVVVNTLAGKASTLECETSAVPAPSISWYKNGRVVTESANLRILKEGQMLEIKTTG-- 1049 Query: 76 VHSDAGVYWCEAT------------NSYGTAR----SRNATLHVAVLREEF-----RLE- 113 SD G Y C+AT N YG AR + ++ A + +F R+E Sbjct: 1050 -VSDTGQYVCKATNIAGQVDKNFHLNVYGRARLSVFTHESSCICATMPSQFSAVPPRIEG 1108 Query: 114 PESKQSAQ--GDTVVLECLPPRGSPEPNVYWKKNGQTL---LFDGDSRMHL--------- 159 P + A+ G+ V C G P P + W KNG+ + F SR+ + Sbjct: 1109 PAEEDIAETLGNPVSFAC-DATGIPPPALAWLKNGRPIGGAAFPSFSRLEMEKCVPLAFT 1167 Query: 160 ----------------VDGGNLVIQDARQ--TDAGRYQCIARNAAGTRESAIATLKIHIK 201 + G +Q AR +D+G Y C+A N G R L I + Sbjct: 1168 CPCELFSENSESLEMHIFSGGGKLQIARSQVSDSGTYTCVASNVEG-RAHKSYRLTIRVP 1226 Query: 202 PYLITG---PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN-MPLGRVKVLDDG-S 256 P I+G P ++ S+ C+ G P P + W + N +++ DG + Sbjct: 1227 P-RISGSELPREMGVLLNESIQLVCQASGTPTPTIQWLKDGEAVNHTGSSELRISPDGTT 1285 Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV---ARFT 313 L + D G Y+C A N+ G L VY PP IN +V + + Sbjct: 1286 LTVFGAHATDGGTYACVATNAAGEEDRIFNLNVYAPPVINGDSETVEERTAVLDASVSLE 1345 Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373 C ATG P P + W G + P S H + G VL I + +DS C Sbjct: 1346 CVATGSPPPQLNWLRNG---LPLPLSS----HVRLLSAG-QVLRITRSQVSDS-GAYSCI 1396 Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEPIIAW 431 A N AG L V PP + S + + + +M C A TP P ++W Sbjct: 1397 ASNRAGVDSRHYNLQV-----HVPPGLDGAGSTEDVTVVGGNMVSLLCVADGTPTPTVSW 1451 Query: 432 YFEGEALI-QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 EG AL ++ R + + ++ + +++G Y+CVA + G+ Sbjct: 1452 LKEGSALFPASNLRFLNLNMSMQIPQAHVNNTGRYSCVAKNTAGQ 1496 Score = 102 bits (244), Expect = 7e-20 Identities = 85/283 (30%), Positives = 123/283 (43%), Gaps = 25/283 (8%) Query: 202 PYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR---VKVLDDGS- 256 P I G E + G V C+ P P + WR+ PL R + VL DGS Sbjct: 2 PPNIQGEELNATVMLGGPVVLHCQSDAIPPPTLSWRKDG----RPLFRKPGLTVLSDGSV 57 Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS--PNSVNVESGNVARFTC 314 LR+D+ + D G YSCEA N G + L V+ PSI S P + V GN C Sbjct: 58 LRVDSAQVQDSGRYSCEATNVAGKTEKNYNLNVWVAPSIRGSEEPTPLTVIEGNPITMVC 117 Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374 ++G P P++ W +G+ V G L I+ + D+ + C+A Sbjct: 118 ESSGIPPPSLVWRKDGSEL--------KPTQRLRVLSGGRQLQISSAARTDTA-SYSCTA 168 Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYF 433 + +G + L V RP ++ G S+ K V C A P P + W Sbjct: 169 SSASGITSKEYSLQVYV---RPSIKLSEGLSDDVAVTKGGDVTLQCAAEGIPRPAVTWLK 225 Query: 434 EGEALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHGK 475 +G + HR V N+G L+ +K + SD+G YTCVA + G+ Sbjct: 226 DGRPVSGQHRAKVLNEGRLLQIKTVKVSDTGRYTCVAVNAAGQ 268 Score = 92.3 bits (219), Expect = 7e-17 Identities = 90/318 (28%), Positives = 130/318 (40%), Gaps = 29/318 (9%) Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74 ++ P +V+V P L+C A G P PAI W K G V + + +L G LR H Sbjct: 287 VDVPENVSVVLKNPVALSCEASGIPLPAISWLKDGQPVRASSSVHVLSGGR--SLRLMHA 344 Query: 75 RVHSDAGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEPESKQSAQGDTVVLECLP 131 V D G Y C +N G R +N L + V + EE + + T+ E Sbjct: 345 AV-GDGGRYTCVVSNMAGEER-KNFDLDILVPPSIEEEGTVVDTKVKEKHNLTLTCEV-- 400 Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191 G+P P + W K+GQ L+ D ++ +G L I R D GRY C+A N+AG R S Sbjct: 401 -SGNPVPGIKWLKDGQMLVSDRHHQV-FSNGRFLQIFGTRVADTGRYSCLASNSAGER-S 457 Query: 192 AIATLKIHIKPYLI-TGP----EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 L + + P + +GP E+V S + C P V W R G Sbjct: 458 RHYNLNVLVSPTIAGSGPEGSVEEVTVTASSPTSLLCDAQSYPPAVVTWLRD-GSSFESS 516 Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306 V+VL + L + EG S A G++T L +N + Sbjct: 517 DHVRVLP--GVTLGMTVKMSEGIRSL-------AYGCHGFITPASAGGRTL--QILNAKE 565 Query: 307 GNVARFTCTATGRPEPTM 324 + R+TC A T+ Sbjct: 566 EDAGRYTCVAANEAGETL 583 Score = 88.6 bits (210), Expect = 9e-16 Identities = 91/353 (25%), Positives = 146/353 (41%), Gaps = 43/353 (12%) Query: 162 GGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL----ITG----PEDVVA 213 G L I +A++ DAGRY C+A N AG LK+ + P++ I G P++V Sbjct: 555 GRTLQILNAKEEDAGRYTCVAANEAGETLKHYE-LKVFVPPHINRNDIPGEGLKPKEVKV 613 Query: 214 QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL-RLDNVILADEGEYSC 272 + SS+T +C P P + W + G + + G + ++++ ++D G Y+C Sbjct: 614 KVNSSLTLECAAQAFPSPALQWYKD-GQILQVDDHMSITASGRMVQVEHARVSDTGRYTC 672 Query: 273 EAENSVGAVSASGYLTVYDPPSINL------SPNSVNVES-------GNVARFTCTATGR 319 A N G + V PP+ S +S VE N C Sbjct: 673 VATNIAGEDEKDFDVNVQVPPNFTRAGGAAGSTSSPGVEGDVRDVILNNPISLYCETNAV 732 Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379 P PT+ W +G S DK + G VL I D+ +C AVN AG Sbjct: 733 PPPTLTWYKDGQLLA-----SGDK---VLILPGGRVLQIPRAQAEDA-GRYICMAVNEAG 783 Query: 380 SSFVRGKLTVTSDDDRPPPII----TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG 435 + + V PPII ++ P T+ + C A P P ++W+ + Sbjct: 784 EDSIHYDVRVLL-----PPIIRGTVSDFPEEVTVLVNKTTQLECHADGNPAPRVSWFQDS 838 Query: 436 EALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 + + + R + ++G ++ + SD+G Y CVA++ G S L V P Sbjct: 839 QPVRPDGRHRILSNGRILQVLTAQVSDTGRYVCVAANVAGSAEKSFNLNVHVP 891 Score = 44.0 bits (99), Expect = 0.025 Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 4/92 (4%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 +T AP I E+P+ V LNC+A G P+P I W + G ++ + S L G Sbjct: 2414 LTLQRAPTITEEPVGTVVDAGSTVVLNCQAEGEPTPTIEWSQQGRPLLGNDRFSSLSNGS 2473 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97 L D Y C A N G+ +R Sbjct: 2474 LRISSVQ----KEDTARYECVARNLVGSVLAR 2501 >UniRef50_Q4SL83 Cluster: Chromosome 7 SCAF14557, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 7 SCAF14557, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 949 Score = 203 bits (496), Expect = 2e-50 Identities = 117/295 (39%), Positives = 160/295 (54%), Gaps = 13/295 (4%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSD---THRSILPAG 64 AP I+ P DV V PA L+CRA GSP + W + G + +D +L G Sbjct: 8 APRIVHHPSDVVVKPGNPARLSCRAEGSPQVSFEWLRNGQPLQVTKADGPMVQPMVLSEG 67 Query: 65 GLFFLRATHGRVH-SDAGVYWCEATNSYGTARSRNATLHVA-VLREEFRLEPESKQSAQG 122 LFFL GR S GVY C A N+ GTA SRNA+L +A +++EEF ++P + A+G Sbjct: 68 SLFFLSVGEGRGGPSHEGVYACVARNAAGTAVSRNASLRIAGMMKEEFSVQPSDVEVAEG 127 Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMH--LVDGGNLVIQDARQTDAGRYQ 179 + VL C PP G P+PNV WKK+G + + D + V G L++ A + ++G Y Sbjct: 128 EVAVLNCGPPTGRPDPNVLWKKDGVPINVTDPHFTVSGSKVLSGKLIVAPAEKKNSGSYV 187 Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239 C+A N G RES A L + KP L+ PE+ + G S F C+ GDP P V+W R Sbjct: 188 CVAANTVGVRESRAARLSVLAKPTLLLKPENASVRLGESAQFYCQAKGDPPPTVVWSREQ 247 Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294 G +P GR V D +L++ V + D G Y+C A N VG V+AS L V + S Sbjct: 248 --GPLPNGRYLVNPDQTLQIHYVTVQDAGTYTCTAANDVGVVTASAQLLVQEAAS 300 Score = 93.5 bits (222), Expect = 3e-17 Identities = 87/301 (28%), Positives = 131/301 (43%), Gaps = 28/301 (9%) Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-----GNMPLGRVKVLDD 254 + P ++ P DVV + G+ CR G P W R+ + P+ + VL + Sbjct: 7 VAPRIVHHPSDVVVKPGNPARLSCRAEGSPQVSFEWLRNGQPLQVTKADGPMVQPMVLSE 66 Query: 255 GSLRLDNVIL-----ADEGEYSCEAENSVG-AVSASGYLTVYD--PPSINLSPNSVNVES 306 GSL +V + EG Y+C A N+ G AVS + L + ++ P+ V V Sbjct: 67 GSLFFLSVGEGRGGPSHEGVYACVARNAAGTAVSRNASLRIAGMMKEEFSVQPSDVEVAE 126 Query: 307 GNVARFTC-TATGRPEPTMFWSVEGNR-TIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 G VA C TGRP+P + W +G + P + + V G L + +K Sbjct: 127 GEVAVLNCGPPTGRPDPNVLWKKDGVPINVTDPHFT---VSGSKVLSGK--LIVAPAEKK 181 Query: 365 DSRNTIVCSAVNYAGSSFVRG-KLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423 +S + VC A N G R +L+V + P + P N ++ + A F C A Sbjct: 182 NS-GSYVCVAANTVGVRESRAARLSVLAK-----PTLLLKPENASVRLGESAQFYCQAKG 235 Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483 P P + W E + + N R V D TL + + D+GTYTC A++ G S LL Sbjct: 236 DPPPTVVWSRE-QGPLPNGRYLVNPDQTLQIHYVTVQDAGTYTCTAANDVGVVTASAQLL 294 Query: 484 V 484 V Sbjct: 295 V 295 Score = 87.8 bits (208), Expect = 2e-15 Identities = 76/226 (33%), Positives = 104/226 (46%), Gaps = 20/226 (8%) Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLF---DGD--SRMHLVDGGN--LVIQDAR--Q 172 G+ L C GSP+ + W +NGQ L DG M L +G L + + R Sbjct: 23 GNPARLSCRA-EGSPQVSFEWLRNGQPLQVTKADGPMVQPMVLSEGSLFFLSVGEGRGGP 81 Query: 173 TDAGRYQCIARNAAGTRESAIATLKIH--IKPYLITGPEDVVAQTGSSVTFQCRVG-GDP 229 + G Y C+ARNAAGT S A+L+I +K P DV G C G P Sbjct: 82 SHEGVYACVARNAAGTAVSRNASLRIAGMMKEEFSVQPSDVEVAEGEVAVLNCGPPTGRP 141 Query: 230 LPDVLWRRSAGGGNMP-----LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSA 283 P+VLW++ N+ + KVL G L + + G Y C A N+VG S Sbjct: 142 DPNVLWKKDGVPINVTDPHFTVSGSKVLS-GKLIVAPAEKKNSGSYVCVAANTVGVRESR 200 Query: 284 SGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVE 329 + L+V P++ L P + +V G A+F C A G P PT+ WS E Sbjct: 201 AARLSVLAKPTLLLKPENASVRLGESAQFYCQAKGDPPPTVVWSRE 246 Score = 62.5 bits (145), Expect = 7e-08 Identities = 47/179 (26%), Positives = 79/179 (44%), Gaps = 8/179 (4%) Query: 659 YYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKP 718 +YL+G + +R L ++ K + + ++ L++ KYEF + P+ G+ Sbjct: 344 HYLDGFEVLYRSLLPAGSDWAAKKV--TMPAFQCQLGPLKRGFKYEFKVRPYGSNLYGRE 401 Query: 719 SNSRVAQTLDDVPDGPPINIEMFILN--TTTVHLKWSPPELQLQNGIITGYNVVVNWLDV 776 SN++ + + VP P + + + + T+HL W PP L NGI+ GY V W V Sbjct: 402 SNTQHLRVPETVPSASPQTVSISVSHEQNNTIHLSWEPPPLDTHNGILQGYQV---WC-V 457 Query: 777 PANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVG 835 + + T L + L G Y + IAA G+G S F I+ + G Sbjct: 458 ESEEQQYQNWTVNSSQKKLDIPALKPGKQYWITIAAVNGAGVGVPSDPHGFLINPQKNG 516 >UniRef50_Q92626 Cluster: Peroxidasin homolog; n=49; Eumetazoa|Rep: Peroxidasin homolog - Homo sapiens (Human) Length = 1496 Score = 201 bits (491), Expect = 8e-50 Identities = 122/387 (31%), Positives = 190/387 (49%), Gaps = 23/387 (5%) Query: 107 REEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV 166 R EP+ G+TV C G+P+P + W +N L DSR++L+D G L+ Sbjct: 262 RPRITSEPQDADVTSGNTVYFTCRA-EGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLM 320 Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATLKIH---IKPYLITGPEDVVAQTGSSVTFQC 223 IQ+ ++TD G YQC+A+N AG ++ TL+ +P + P++ G SVT +C Sbjct: 321 IQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLEC 380 Query: 224 RVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA 280 G P P + W R G PL RV + G L + NV+ D GEY+C A N++ + Sbjct: 381 SATGHPPPRISWTR---GDRTPLPVDPRVNITPSGGLYIQNVVQGDSGEYACSATNNIDS 437 Query: 281 VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340 V A+ ++ V P ++P V G F C A G P P + W+ G++ +S Sbjct: 438 VHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQ------LS 491 Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII 400 D+ H V T L I+ +D + C AVN GS V LTV R P+ Sbjct: 492 VDRRH--LVLSSGT-LRISGVALHD-QGQYECQAVNIIGSQKVVAHLTV---QPRVTPVF 544 Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS 460 + PS+ T+ + + PC++ PEP I W +G + ++ + +++ +G L + D+ + Sbjct: 545 ASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEGFLTINDVGPA 604 Query: 461 DSGTYTCVASSRHGKYVWSGALLVDSP 487 D+G Y CVA + G S L V+ P Sbjct: 605 DAGRYECVARNTIGSASVSMVLSVNVP 631 Score = 171 bits (417), Expect = 7e-41 Identities = 119/391 (30%), Positives = 181/391 (46%), Gaps = 26/391 (6%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG--VLVVSDTHRSILPAGGLF 67 E P I +P D V CRA G+P P I W + + + +D+ ++L G L Sbjct: 261 ERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLM 320 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV--AVLREEFRLEPESKQSAQGDTV 125 +D G+Y C A N G +++ TL + R F ++P++ + G++V Sbjct: 321 I----QNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESV 376 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 LEC G P P + W + +T L D R+++ G L IQ+ Q D+G Y C A N Sbjct: 377 TLEC-SATGHPPPRISWTRGDRTPL-PVDPRVNITPSGGLYIQNVVQGDSGEYACSATNN 434 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 + A A + + P P+D V G +V FQC G+P P + W + GG + Sbjct: 435 IDS-VHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTK--GGSQLS 491 Query: 246 LGRVK-VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PPSINLSPNSV 302 + R VL G+LR+ V L D+G+Y C+A N +G+ +LTV P P+ Sbjct: 492 VDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDT 551 Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362 VE G + C++ G PEP + W+ +G + K+H + +G LTIND Sbjct: 552 TVEVGANVQLPCSSQGEPEPAITWNKDGVQV-----TESGKFHISP--EG--FLTINDVG 602 Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393 D+ C A N GS+ V L+V D Sbjct: 603 PADA-GRYECVARNTIGSASVSMVLSVNVPD 632 Score = 138 bits (333), Expect = 1e-30 Identities = 91/291 (31%), Positives = 138/291 (47%), Gaps = 14/291 (4%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPA 63 Y S P + QP + V + TL C A G P P I W +G + D +I P+ Sbjct: 352 YFGSPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPS 411 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123 GGL+ G D+G Y C ATN+ + + A + V L +F + P+ + +G Sbjct: 412 GGLYIQNVVQG----DSGEYACSATNNIDSVHA-TAFIIVQAL-PQFTVTPQDRVVIEGQ 465 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIA 182 TV +C +G+P P + W K G L D R HLV G L I D G+Y+C A Sbjct: 466 TVDFQC-EAKGNPPPVIAWTKGGSQLSVD---RRHLVLSSGTLRISGVALHDQGQYECQA 521 Query: 183 RNAAGTRE-SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241 N G+++ A T++ + P + P D + G++V C G+P P + W + G Sbjct: 522 VNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKD-GV 580 Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292 G+ + +G L +++V AD G Y C A N++G+ S S L+V P Sbjct: 581 QVTESGKFHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVLSVNVP 631 Score = 107 bits (258), Expect = 1e-21 Identities = 82/295 (27%), Positives = 126/295 (42%), Gaps = 19/295 (6%) Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGSLRL 259 +P + + P+D +G++V F CR G+P P+++W R+ +M R+ +LDDG+L + Sbjct: 262 RPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLMI 321 Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVY--DP--PSINLSPNSVNVESGNVARFTCT 315 N D+G Y C A+N G V Y P P+ + P + V G C+ Sbjct: 322 QNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLECS 381 Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375 ATG P P + W+ G+RT + P R + G+ + + D + CSA Sbjct: 382 ATGHPPPRISWT-RGDRTPL-PVDPRVNITPSG---GLYIQNVVQGDSGE----YACSAT 432 Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG 435 N S + V + P T P ++ + F C A P P+IAW G Sbjct: 433 NNIDSVHATAFIIVQA-----LPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGG 487 Query: 436 EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490 L + R V + GTL + + D G Y C A + G L V + P Sbjct: 488 SQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTP 542 >UniRef50_Q4SR23 Cluster: Chromosome 11 SCAF14528, whole genome shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 11 SCAF14528, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 900 Score = 187 bits (456), Expect = 1e-45 Identities = 148/510 (29%), Positives = 219/510 (42%), Gaps = 51/510 (10%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 +NCRA G+P P RW G + +++ + A G ++ H V + GVY C ATN+ Sbjct: 24 INCRAKGNPPPHYRWTVDGREISTESDPNYSLAEGNLLIKNPH--VVNHRGVYQCIATNT 81 Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150 +GT SR A + A L R +G VVL C PP E W NG+ Sbjct: 82 FGTIVSRQAKVQFAFLENFSRKSRSIVSVREGQAVVLLCGPPLHYGEIKYSWVFNGRRGF 141 Query: 151 FDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG-- 207 D+R + GNL I DAG Y C RN + + ++ + G Sbjct: 142 LQQDARRFISQRTGNLYIAKVEALDAGNYTCAVRNMMTNATVFSSPTPVVVRGDAVMGEY 201 Query: 208 --------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLR 258 P+ + GSSVT +C G+P+P + WRR A G +P G++K+ G L Sbjct: 202 EPKIEVQFPDTLRVSKGSSVTLECFALGNPVPSISWRR-ADGNPLP-GKIKINHSTGVLE 259 Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL--SPNSVNVESGNVARFTCTA 316 + D G Y C AENS G A G L + + +P ++ G ++ C A Sbjct: 260 IPYFRPEDAGVYECVAENSRGLNVARGQLLFQNVEHLQWVHTPKDADIAIGASLQWECKA 319 Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376 G P P W G I P + + A +T ++++D+ C A N Sbjct: 320 MGNPRPAYKWLKNGQ---ILP--KEGEIYVEAGKLSITRISLSDSGMYQ------CVAHN 368 Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK--SMAVFPCTAICTPEPIIAWYFE 434 GS + +L V + PP T P ++ ++ AV C +P + +W+ Sbjct: 369 EHGSVYASAELKVVAS----PPDFTLRPVKKSTVVQRGGEAVLECRPYASPRAVTSWWRG 424 Query: 435 GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHF 494 GE L R+ V +DGTL + ++ K D G YTCVA + G +G L+V P Sbjct: 425 GELLKDTERQTVMDDGTLRITNISKFDGGRYTCVARNHFGTSSSTGTLVVKGP------- 477 Query: 495 FRAADVSSLPGPPTKPITHNVTDTSVTLSW 524 PGPP +++DT+V LSW Sbjct: 478 ---------PGPPEALAVTDISDTTVQLSW 498 Score = 91.9 bits (218), Expect = 1e-16 Identities = 72/218 (33%), Positives = 103/218 (47%), Gaps = 17/218 (7%) Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74 + P D +A C+A G+P PA +W K G ++ + + AG L R + Sbjct: 299 VHTPKDADIAIGASLQWECKAMGNPRPAYKWLKNGQILPKE-GEIYVEAGKLSITRIS-- 355 Query: 75 RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA--QGDTVVLECLPP 132 SD+G+Y C A N +G+ + +A L V +F L P K + +G VLEC P Sbjct: 356 --LSDSGMYQCVAHNEHGSVYA-SAELKVVASPPDFTLRPVKKSTVVQRGGEAVLEC-RP 411 Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192 SP W + G+ LL D + R ++D G L I + + D GRY C+ARN GT S+ Sbjct: 412 YASPRAVTSWWRGGE-LLKDTE-RQTVMDDGTLRITNISKFDGGRYTCVARNHFGT-SSS 468 Query: 193 IATLKIHIKPYLITGPEDVVAQTG-SSVTFQCRVGGDP 229 TL + P GP + +A T S T Q G P Sbjct: 469 TGTLVVKGPP----GPPEALAVTDISDTTVQLSWGSGP 502 Score = 65.7 bits (153), Expect = 7e-09 Identities = 45/122 (36%), Positives = 60/122 (49%), Gaps = 5/122 (4%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I P++ T+ R++ +C A GSP P+ RW G + S + +GG LR Sbjct: 738 PGSIVYPVE-TLERNKEVVFSCEAQGSPPPSYRWKLNGTEISSKYGSHYILSGGN--LRI 794 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLECL 130 DAG Y C A+NS+GT SR A+L A L E F+ S +G VVL C Sbjct: 795 NRLNKDQDAGTYQCLASNSFGTIVSREASLTFAYL-ENFKTHRRSSVFVREGQGVVLLCG 853 Query: 131 PP 132 PP Sbjct: 854 PP 855 Score = 51.2 bits (117), Expect = 2e-04 Identities = 34/101 (33%), Positives = 49/101 (48%), Gaps = 4/101 (3%) Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA-RQTDAGRYQCIAR 183 VV C +GSP P+ WK NG + S +++ GGNL I + DAG YQC+A Sbjct: 754 VVFSC-EAQGSPPPSYRWKLNGTEISSKYGSH-YILSGGNLRINRLNKDQDAGTYQCLAS 811 Query: 184 NAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQC 223 N+ GT S A+L +++ + V + G V C Sbjct: 812 NSFGTIVSREASLTFAYLENFKTHRRSSVFVREGQGVVLLC 852 Score = 44.8 bits (101), Expect = 0.015 Identities = 48/173 (27%), Positives = 78/173 (45%), Gaps = 13/173 (7%) Query: 663 GLFIYFRPLDNITIEYEMKTILHSNDVSGF--EITSLRKYTKYEFFLIPFYKKFEGKPSN 720 G + FRP + T ++T+L S D S + + S+ T +E + + EG+ S Sbjct: 565 GYIVAFRPAGSSTW---IQTVLASPDASRYIYKDDSIEPLTLFEVKVGVYNSIGEGQFSR 621 Query: 721 SRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANK 780 + ++ P+ PP NIE + N + + L W + +TGY VV A Sbjct: 622 MVRVFSAEEAPNRPPSNIEWKLTN-SKIFLNWEHVKAMENESEVTGYKVVYR----QAWN 676 Query: 781 SMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRS 833 SM ++ T TS+ + + SG +Y ++I A T G G S + SRS Sbjct: 677 SMTSVLET--NKTSMAL-QIPSGENYLIEIKALTEGGDGSSSGPIRIPKMSRS 726 Score = 42.7 bits (96), Expect = 0.059 Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 7/87 (8%) Query: 398 PIITNGPSNQTLPIKSM-----AVFPCTAICTPEPIIAWYFEGEALIQNHRRN-VTNDGT 451 P+ T P + P++++ VF C A +P P W G + + + + + G Sbjct: 732 PVFTKQPGSIVYPVETLERNKEVVFSCEAQGSPPPSYRWKLNGTEISSKYGSHYILSGGN 791 Query: 452 LVLKDLDKS-DSGTYTCVASSRHGKYV 477 L + L+K D+GTY C+AS+ G V Sbjct: 792 LRINRLNKDQDAGTYQCLASNSFGTIV 818 Score = 40.3 bits (90), Expect = 0.31 Identities = 25/95 (26%), Positives = 41/95 (43%), Gaps = 2/95 (2%) Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247 +R S + + +P I P + + + V F C G P P W+ + + G Sbjct: 724 SRSSILQSPVFTKQPGSIVYPVETL-ERNKEVVFSCEAQGSPPPSYRWKLNGTEISSKYG 782 Query: 248 RVKVLDDGSLRLDNVIL-ADEGEYSCEAENSVGAV 281 +L G+LR++ + D G Y C A NS G + Sbjct: 783 SHYILSGGNLRINRLNKDQDAGTYQCLASNSFGTI 817 >UniRef50_Q4S2G3 Cluster: Chromosome undetermined SCAF14761, whole genome shotgun sequence; n=2; Clupeocephala|Rep: Chromosome undetermined SCAF14761, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 2528 Score = 186 bits (454), Expect = 2e-45 Identities = 141/474 (29%), Positives = 211/474 (44%), Gaps = 33/474 (6%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 +T E+P I +V V H L C A G P P+I W + GV + + S+L G Sbjct: 1263 LTVQESPEIGPMAEEVQVVLHHGTVLPCEAQGFPRPSITWQREGVSIATGHRLSVLSNGA 1322 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNA-TLHVAVLREEFRLEPESKQSAQGDT 124 L F R T G DAG+Y C A N G A R L V + R+E S G Sbjct: 1323 LKFSRVTLG----DAGMYQCLAKNEAGVAVGRTRLVLQVPPVLSVPRME---YTSVLGQP 1375 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 V LEC+ G P P V W K + ++ +G + + + G L I +++DAG Y C A+N Sbjct: 1376 VSLECVAD-GQPPPEVAWLKERRPVI-EG-AHIRIFANGTLAIASTQRSDAGLYTCTAKN 1432 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GN 243 AG R S L I + P + D+ G C G P P + W ++ N Sbjct: 1433 LAG-RASHDMRLAIQVPPLISPAQTDLSVVQGFQALLPCAAQGSPEPRISWEKNGTPVPN 1491 Query: 244 MPLGRVKVLDDGSLRLDN--VILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301 +P G+ VL G L ++ V AD G ++C A N+ G+ L++ P+ P Sbjct: 1492 LP-GKYTVLRSGELIIERAEVSWADAGVFTCVATNTAGSARQDSRLSINMRPAFKELPGD 1550 Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361 V + G +C A G P P + W+V + G + D+ G + L I + Sbjct: 1551 VTLNKGQNLALSCHAQGTPPPVISWTVNNSPQT---GATLDE-------SGRSSLIIENV 1600 Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN-GPSNQTLPIKSMAVFPCT 420 + + T VC A N GS + V R PP++ +QT+ S A+ C Sbjct: 1601 TTSHA-GTYVCIAENSVGSIRALSFVRV-----REPPVLKGEARMSQTVVQGSSAILDCP 1654 Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 P P++ W +G L+++HR +G+LV+ ++ +D G Y C+A S G Sbjct: 1655 IHGDPSPVLQWLRDGHPLLRSHRIQALLNGSLVIYSINAADEGEYQCLAESEAG 1708 Score = 169 bits (412), Expect = 3e-40 Identities = 142/472 (30%), Positives = 217/472 (45%), Gaps = 40/472 (8%) Query: 17 QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV 76 + L+ T+ H TL+C+A G P P+I W K G + S G L Sbjct: 445 ESLNYTLGSH--VTLSCQASGFPVPSITWLKDGTPIESSLQWQWSIRGNRLELGPL---T 499 Query: 77 HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLECLPPRGS 135 + GVY C A NS G + ++ L V V E S+ SA G+ + LEC G+ Sbjct: 500 LAHGGVYTCVAENSEGQTQ-KDYALTVQVSPTILDSEHPSEVSAPMGEELSLEC-QATGN 557 Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLV---DGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192 P P++ W K+G ++ +G H+V +G L + D+G Y C+A + AG R++ Sbjct: 558 PTPHLSWLKDG--VIVEGSDNRHIVATPEGSALTLLRLSPDDSGTYTCLAVSPAG-RQTK 614 Query: 193 IATLKIHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249 I TL + + P + T P +V S VT +C+V G P P + W ++ G + R Sbjct: 615 IYTLFVLVPPSIAGETTVPREVPVTQDSVVTLECQVAGSPPPQISWLKN-GHPLLLSPRT 673 Query: 250 KVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN-LSP-NSVNVES 306 ++L D LR+ V L+D G Y+C A + G S + V PP ++ + P V + Sbjct: 674 RLLSADSVLRISPVQLSDSGVYTCVARSQAGLAELSYDVQVQVPPGVDHVEPVEPVTIVQ 733 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV-TVLTINDTDKND 365 G++ +C A G P PT+ W +G + H + DG T L + D +D Sbjct: 734 GSLVTLSCEARGVPPPTLTWFKDGQPLSL---------HRNLLLDGQETRLQLPDVATSD 784 Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN-GPSNQTLPIKSMAVFPCTAICT 424 + C A N AGSS LTV PP + ++ P T+ + S C+A Sbjct: 785 A-GLYSCVASNQAGSSTKTFNLTVLE----PPKMTSSTSPEELTIAVNSPLELECSATGV 839 Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHGK 475 P P + W +G L + V DG L+ + + D+G YTC+ASS G+ Sbjct: 840 PPPTLTWLKDGHPLELSD--IVQEDGHLIRISKVQVEDAGLYTCLASSLAGE 889 Score = 161 bits (391), Expect = 1e-37 Identities = 143/464 (30%), Positives = 198/464 (42%), Gaps = 29/464 (6%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 +V+V + +L C P P I W + G ++ + ILP G + L+ R+ D Sbjct: 261 EVSVTEGRMVSLLCDVQAYPPPEITWTRDGQVLAFGSGIHILPGGQM--LQLPRARLE-D 317 Query: 80 AGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEPESKQSAQGDTVVLECLPPRGSP 136 AG Y C ATNS G + ++ L V V L+ + G +V+L C G P Sbjct: 318 AGQYVCTATNSAGQDQ-KSILLSVYVRPSLKPRLDAASDLVTPQVGSSVILSC-EAHGVP 375 Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196 EP V W KNG L M D L I + D G Y C N AG + L Sbjct: 376 EPEVTWYKNGLQLAPRNGFEM---DRYQLEIVGVQVADDGTYTCKVSNVAGQVDRTFR-L 431 Query: 197 KIHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255 +H+ P L + + T GS VT C+ G P+P + W + L + Sbjct: 432 TVHVPPVLEGSLWESLNYTLGSHVTLSCQASGFPVPSITWLKDGTPIESSLQWQWSIRGN 491 Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS--PNSVNVESGNVARFT 313 L L + LA G Y+C AENS G LTV P+I S P+ V+ G Sbjct: 492 RLELGPLTLAHGGVYTCVAENSEGQTQKDYALTVQVSPTILDSEHPSEVSAPMGEELSLE 551 Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373 C ATG P P + W +G +I G D H A +G + LT+ +DS T C Sbjct: 552 CQATGNPTPHLSWLKDG---VIVEGS--DNRHIVATPEG-SALTLLRLSPDDS-GTYTCL 604 Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK--SMAVFPCTAICTPEPIIAW 431 AV+ AG L V PP I + +P+ S+ C +P P I+W Sbjct: 605 AVSPAGRQTKIYTLFVLV----PPSIAGETTVPREVPVTQDSVVTLECQVAGSPPPQISW 660 Query: 432 YFEGEALIQNHR-RNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 G L+ + R R ++ D L + + SDSG YTCVA S+ G Sbjct: 661 LKNGHPLLLSPRTRLLSADSVLRISPVQLSDSGVYTCVARSQAG 704 Score = 159 bits (386), Expect = 4e-37 Identities = 147/541 (27%), Positives = 242/541 (44%), Gaps = 46/541 (8%) Query: 4 DY-VTSGEAPYII--EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI 60 DY +T +P I+ E P +V+ + +L C+A G+P+P + W K GV+V +R I Sbjct: 520 DYALTVQVSPTILDSEHPSEVSAPMGEELSLECQATGNPTPHLSWLKDGVIVEGSDNRHI 579 Query: 61 L--PAG-GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEP 114 + P G L LR + D+G Y C A + G +++ TL V V + E + P Sbjct: 580 VATPEGSALTLLRLS----PDDSGTYTCLAVSPAG-RQTKIYTLFVLVPPSIAGETTV-P 633 Query: 115 ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTD 174 Q V LEC GSP P + W KNG LL +R+ D L I + +D Sbjct: 634 REVPVTQDSVVTLEC-QVAGSPPPQISWLKNGHPLLLSPRTRLLSAD-SVLRISPVQLSD 691 Query: 175 AGRYQCIARNAAGTRESAIATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPD 232 +G Y C+AR+ AG E + +++ + P + + E V GS VT C G P P Sbjct: 692 SGVYTCVARSQAGLAELSY-DVQVQVPPGVDHVEPVEPVTIVQGSLVTLSCEARGVPPPT 750 Query: 233 VLWRRSAGGGNMPLGRVKVLD--DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290 + W + G + L R +LD + L+L +V +D G YSC A N G+ + + LTV Sbjct: 751 LTWFKD--GQPLSLHRNLLLDGQETRLQLPDVATSDAGLYSCVASNQAGSSTKTFNLTVL 808 Query: 291 DPPSI--NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348 +PP + + SP + + + C+ATG P PT+ W +G+ + + D + Sbjct: 809 EPPKMTSSTSPEELTIAVNSPLELECSATGVPPPTLTWLKDGHPLELSDIVQEDGH---- 864 Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQ 407 ++ I+ D+ C A + AG + V PP + ++ Sbjct: 865 ------LIRISKVQVEDA-GLYTCLASSLAGEDGKNHWIRV----QVPPTLFGSDEVKTL 913 Query: 408 TLPIKSMAVFPCTAICTPEPIIAWY-FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYT 466 T+P+ C A P P I WY E + + + + L ++++ DSG Y+ Sbjct: 914 TVPVNGHLTLECLADSDPAPEIEWYKDEVKVQLGGRVQQLAGGQYLEIQEVRPEDSGLYS 973 Query: 467 CVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQ 526 CV ++ G S V+ + P I +++V++ G + D T++W + Sbjct: 974 CVVTNMAGSS--SLFFTVEILLPPKIR-ESSSEVTTHVGQDALLLCEVEEDAQATVTWRK 1030 Query: 527 N 527 + Sbjct: 1031 D 1031 Score = 159 bits (385), Expect = 6e-37 Identities = 132/477 (27%), Positives = 189/477 (39%), Gaps = 24/477 (5%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I E +VT Q A L C + W K G + D ++L G L Sbjct: 995 PKIRESSSEVTTHVGQDALLLCEVEEDAQATVTWRKDGFPITQDHKYTLLSEGSL----R 1050 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131 H SDAG Y+C +N G+ R L V V P + G VL C Sbjct: 1051 VHDVQLSDAGRYYCSVSNQAGSDH-RGIYLRVFVA-PAISPGPFNVTVTAGMRAVLSC-E 1107 Query: 132 PRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190 G P P V WK+NG+ L + L+ G+LV+ D G ++C A N AG E Sbjct: 1108 TTGIPPPKVSWKRNGKPLDVSQLSGAFRLLSSGSLVLLSPSDEDEGYFECTAVNDAG-EE 1166 Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250 + + + + P + V A S V C V G P P V+W +S + G + Sbjct: 1167 RRVVEVILQVPPTIEDDVTAVTAVKMSPVALPCHVQGRPQPTVVWTKSGAKLSSRGGTYR 1226 Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310 VL G L + V+ + G Y+C A NS G LTV + P I V V + Sbjct: 1227 VLPTGLLEITAVLPSHAGRYTCSARNSAGLAHKHISLTVQESPEIGPMAEEVQVVLHHGT 1286 Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370 C A G P P++ W EG +S H +V L + D+ Sbjct: 1287 VLPCEAQGFPRPSITWQREG--------VSIATGHRLSVLSN-GALKFSRVTLGDA-GMY 1336 Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA 430 C A N AG + R +L + + PP+++ T + C A P P +A Sbjct: 1337 QCLAKNEAGVAVGRTRLVL-----QVPPVLSVPRMEYTSVLGQPVSLECVADGQPPPEVA 1391 Query: 431 WYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 W E +I+ + +GTL + +SD+G YTC A + G+ L + P Sbjct: 1392 WLKERRPVIEGAHIRIFANGTLAIASTQRSDAGLYTCTAKNLAGRASHDMRLAIQVP 1448 Score = 156 bits (379), Expect = 3e-36 Identities = 126/468 (26%), Positives = 200/468 (42%), Gaps = 33/468 (7%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS--DTHRSILPAGGLFFL 69 P I + VT + P L C G P P + W K G + S T+R +LP G L + Sbjct: 1178 PTIEDDVTAVTAVKMSPVALPCHVQGRPQPTVVWTKSGAKLSSRGGTYR-VLPTG-LLEI 1235 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV-LREEFRLEP--ESKQSAQGDTVV 126 A + S AG Y C A NS G A H+++ ++E + P E Q V Sbjct: 1236 TAV---LPSHAGRYTCSARNSAGLAHK-----HISLTVQESPEIGPMAEEVQVVLHHGTV 1287 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186 L C +G P P++ W++ G ++ R+ ++ G L DAG YQC+A+N A Sbjct: 1288 LPC-EAQGFPRPSITWQREGVSIATG--HRLSVLSNGALKFSRVTLGDAGMYQCLAKNEA 1344 Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 G L + + P L + + G V+ +C G P P+V W + + Sbjct: 1345 GVAVGR-TRLVLQVPPVLSVPRMEYTSVLGQPVSLECVADGQPPPEVAWLKERRPV-IEG 1402 Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306 +++ +G+L + + +D G Y+C A+N G S L + PP I+ + ++V Sbjct: 1403 AHIRIFANGTLAIASTQRSDAGLYTCTAKNLAGRASHDMRLAIQVPPLISPAQTDLSVVQ 1462 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 G A C A G PEP + W G PG KY T + G ++ + D+ Sbjct: 1463 GFQALLPCAAQGSPEPRISWEKNGTPVPNLPG----KY--TVLRSGELIIERAEVSWADA 1516 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426 C A N AGS+ +L++ P P + TL C A TP Sbjct: 1517 -GVFTCVATNTAGSARQDSRLSINM-----RPAFKELPGDVTLNKGQNLALSCHAQGTPP 1570 Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 P+I+W + + +L+++++ S +GTY C+A + G Sbjct: 1571 PVISWTVNNSPQ-TGATLDESGRSSLIIENVTTSHAGTYVCIAENSVG 1617 Score = 156 bits (378), Expect = 4e-36 Identities = 146/541 (26%), Positives = 226/541 (41%), Gaps = 31/541 (5%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80 +TV + TL C A P+P I WYK V V L AGG + L R D+ Sbjct: 913 LTVPVNGHLTLECLADSDPAPEIEWYKDEVKVQLGGRVQQL-AGGQY-LEIQEVRPE-DS 969 Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140 G+Y C TN G++ S T+ + +L + R + G +L C + + V Sbjct: 970 GLYSCVVTNMAGSS-SLFFTVEI-LLPPKIRESSSEVTTHVGQDALLLCEVEEDA-QATV 1026 Query: 141 YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200 W+K+G + D + L+ G+L + D + +DAGRY C N AG+ I L++ + Sbjct: 1027 TWRKDGFPIT--QDHKYTLLSEGSLRVHDVQLSDAGRYYCSVSNQAGSDHRGIY-LRVFV 1083 Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL--GRVKVLDDGSLR 258 P + GP +V G C G P P V W+R+ ++ G ++L GSL Sbjct: 1084 APAISPGPFNVTVTAGMRAVLSCETTGIPPPKVSWKRNGKPLDVSQLSGAFRLLSSGSLV 1143 Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATG 318 L + DEG + C A N G + + PP+I +V + C G Sbjct: 1144 LLSPSDEDEGYFECTAVNDAGEERRVVEVILQVPPTIEDDVTAVTAVKMSPVALPCHVQG 1203 Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378 RP+PT+ W+ G + G R T + + VL + R T CSA N A Sbjct: 1204 RPQPTVVWTKSGAKLSSRGGTYR--VLPTGLLEITAVLP-----SHAGRYT--CSARNSA 1254 Query: 379 GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438 G + LTV + P + + V PC A P P I W EG ++ Sbjct: 1255 GLAHKHISLTVQESPEIGPMA-----EEVQVVLHHGTVLPCEAQGFPRPSITWQREGVSI 1309 Query: 439 IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAA 498 HR +V ++G L + D+G Y C+A + G V L++ P P + R Sbjct: 1310 ATGHRLSVLSNGALKFSRVTLGDAGMYQCLAKNEAGVAVGRTRLVLQVP--PVLSVPR-M 1366 Query: 499 DVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558 + +S+ G P ++W + + I G + +F+ TL+ +T R+ Sbjct: 1367 EYTSVLGQPVSLECVADGQPPPEVAWLKERR---PVIEGAHIRIFANGTLAIASTQRSDA 1423 Query: 559 G 559 G Sbjct: 1424 G 1424 Score = 154 bits (373), Expect = 2e-35 Identities = 157/610 (25%), Positives = 249/610 (40%), Gaps = 53/610 (8%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG----VLVVSDTHRSILPAGGL 66 AP I P +VTV A L+C G P P + W + G V +S R +L +G L Sbjct: 1084 APAISPGPFNVTVTAGMRAVLSCETTGIPPPKVSWKRNGKPLDVSQLSGAFR-LLSSGSL 1142 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARS-RNATLHVAVLREEFRLEPESKQSAQGDTV 125 L + D G + C A N G R L V E+ + + + + V Sbjct: 1143 VLLSPS----DEDEGYFECTAVNDAGEERRVVEVILQVPPTIED---DVTAVTAVKMSPV 1195 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 L C +G P+P V W K+G L G + ++ G L I + AGRY C ARN+ Sbjct: 1196 ALPC-HVQGRPQPTVVWTKSGAKLSSRGGT-YRVLPTGLLEITAVLPSHAGRYTCSARNS 1253 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 AG I +L + P + E+V C G P P + W+R G ++ Sbjct: 1254 AGLAHKHI-SLTVQESPEIGPMAEEVQVVLHHGTVLPCEAQGFPRPSITWQRE--GVSIA 1310 Query: 246 LG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304 G R+ VL +G+L+ V L D G Y C A+N G L + PP +++ Sbjct: 1311 TGHRLSVLSNGALKFSRVTLGDAGMYQCLAKNEAGVAVGRTRLVLQVPPVLSVPRMEYTS 1370 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 G C A G+P P + W E R +I + H +G L I T ++ Sbjct: 1371 VLGQPVSLECVADGQPPPEVAWLKE-RRPVI------EGAHIRIFANG--TLAIASTQRS 1421 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424 D+ C+A N AG + +L + + PP+I+ ++ ++ A+ PC A + Sbjct: 1422 DA-GLYTCTAKNLAGRASHDMRLAI-----QVPPLISPAQTDLSVVQGFQALLPCAAQGS 1475 Query: 425 PEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLK--DLDKSDSGTYTCVASSRHGKYVWSGA 481 PEP I+W G + + V G L+++ ++ +D+G +TCVA++ G Sbjct: 1476 PEPRISWEKNGTPVPNLPGKYTVLRSGELIIERAEVSWADAGVFTCVATNTAGSARQDSR 1535 Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541 L ++ + P DV+ G H +SW+ NN S G ++ Sbjct: 1536 LSIN--MRPAFKEL-PGDVTLNKGQNLALSCHAQGTPPPVISWTVNN----SPQTGATLD 1588 Query: 542 VFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPV 601 R +L N + G V + ++ + I + VR L G + + Sbjct: 1589 ESGRSSLIIENVTTSHAGTYVC---------IAENSVGSIRALSFVRVREPPVLKGEARM 1639 Query: 602 SDSVTVGDDS 611 S +V G + Sbjct: 1640 SQTVVQGSSA 1649 Score = 142 bits (345), Expect = 4e-32 Identities = 141/490 (28%), Positives = 203/490 (41%), Gaps = 49/490 (10%) Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS 78 LDV + P +L+C + P P + W+K G ++S +LP + + Sbjct: 75 LDVVLGH--PVSLSCESNAIPPPKLSWHKDGQKLMSGDGVVLLPGAQVLQIARVQ---KE 129 Query: 79 DAGVYWCEATNSYGTARSRNATLHVAV------LREEFRLEPESKQSAQGDTVVLECLPP 132 DAG Y C+A N G + LH+ V EEF E + TVVL C Sbjct: 130 DAGRYTCQAVNEAGEDH-MHFELHILVPPVITGATEEFM---EEMAAVVNSTVVLHC-DV 184 Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192 G P P V W K+GQ + D ++ DG L + + +D Y C+A N GT E Sbjct: 185 TGQPTPAVSWMKDGQPVQTDPQHQIS-KDGTQLHLLRVQVSDMAGYLCVAENKVGTVEK- 242 Query: 193 IATLKIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR-V 249 + +L + + P ITG E+V G V+ C V P P++ W R G + G + Sbjct: 243 LFSLTVQVPP-RITGRMEEEVSVTEGRMVSLLCDVQAYPPPEITWTRD--GQVLAFGSGI 299 Query: 250 KVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS----INLSPNSVNV 304 +L G L+L L D G+Y C A NS G S L+VY PS ++ + + V Sbjct: 300 HILPGGQMLQLPRARLEDAGQYVCTATNSAGQDQKSILLSVYVRPSLKPRLDAASDLVTP 359 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 + G+ +C A G PEP + W G + G D+Y V GV V Sbjct: 360 QVGSSVILSCEAHGVPEPEVTWYKNGLQLAPRNGFEMDRYQLEIV--GVQVA-------- 409 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP-SNQTLPIKSMAVFPCTAIC 423 T C N AG +LTV PP++ + + S C A Sbjct: 410 -DDGTYTCKVSNVAGQVDRTFRLTV-----HVPPVLEGSLWESLNYTLGSHVTLSCQASG 463 Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482 P P I W +G + + + + G L L L + G YTCVA + G+ AL Sbjct: 464 FPVPSITWLKDGTPIESSLQWQWSIRGNRLELGPLTLAHGGVYTCVAENSEGQTQKDYAL 523 Query: 483 LVDSPINPNI 492 V ++P I Sbjct: 524 TVQ--VSPTI 531 Score = 132 bits (318), Expect = 7e-29 Identities = 125/471 (26%), Positives = 195/471 (41%), Gaps = 41/471 (8%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 L+C A G P P + WYK G+ + + + L +V +D G Y C+ +N Sbjct: 367 LSCEAHGVPEPEVTWYKNGLQLAPRNGFEM----DRYQLEIVGVQV-ADDGTYTCKVSNV 421 Query: 91 YGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149 G R+ T+HV + E E S G V L C G P P++ W K+G T Sbjct: 422 AGQVDRTFRLTVHVPPVLEGSLWE--SLNYTLGSHVTLSC-QASGFPVPSITWLKDG-TP 477 Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG-- 207 + + G L + G Y C+A N+ G + A L + + P ++ Sbjct: 478 IESSLQWQWSIRGNRLELGPLTLAHGGVYTCVAENSEGQTQKDYA-LTVQVSPTILDSEH 536 Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA----GGGNMPLGRVKVLDDGSLRLDNVI 263 P +V A G ++ +C+ G+P P + W + G N + V + +L L + Sbjct: 537 PSEVSAPMGEELSLECQATGNPTPHLSWLKDGVIVEGSDNRHI--VATPEGSALTLLRLS 594 Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPPSI---NLSPNSVNVESGNVARFTCTATGRP 320 D G Y+C A + G + L V PPSI P V V +V C G P Sbjct: 595 PDDSGTYTCLAVSPAGRQTKIYTLFVLVPPSIAGETTVPREVPVTQDSVVTLECQVAGSP 654 Query: 321 EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGS 380 P + W G+ ++ P T + +VL I+ +DS C A + AG Sbjct: 655 PPQISWLKNGHPLLLSP--------RTRLLSADSVLRISPVQLSDS-GVYTCVARSQAGL 705 Query: 381 SFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK-SMAVFPCTAICTPEPIIAWYFEGEALI 439 + +L+ PP + P ++ S+ C A P P + W+ +G+ L Sbjct: 706 A----ELSYDVQVQVPPGVDHVEPVEPVTIVQGSLVTLSCEARGVPPPTLTWFKDGQPL- 760 Query: 440 QNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 + RN+ DG L L D+ SD+G Y+CVAS++ G + L V P Sbjct: 761 -SLHRNLLLDGQETRLQLPDVATSDAGLYSCVASNQAGSSTKTFNLTVLEP 810 Score = 116 bits (278), Expect = 5e-24 Identities = 89/282 (31%), Positives = 142/282 (50%), Gaps = 16/282 (5%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFFLR 70 P I D++V + A L C A GSP P I W K G V + + ++L +G L R Sbjct: 1449 PLISPAQTDLSVVQGFQALLPCAAQGSPEPRISWEKNGTPVPNLPGKYTVLRSGELIIER 1508 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130 A +DAGV+ C ATN+ G+AR +++ L + +R F+ P +G + L C Sbjct: 1509 AEVS--WADAGVFTCVATNTAGSAR-QDSRLSIN-MRPAFKELPGDVTLNKGQNLALSC- 1563 Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190 +G+P P + W N + + +L+I++ + AG Y CIA N+ G+ Sbjct: 1564 HAQGTPPPVISWTVNNSP---QTGATLDESGRSSLIIENVTTSHAGTYVCIAENSVGSIR 1620 Query: 191 SAIATLKIHIKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247 A++ +++ +P ++ G E ++QT GSS C + GDP P + W R G + Sbjct: 1621 -ALSFVRVR-EPPVLKG-EARMSQTVVQGSSAILDCPIHGDPSPVLQWLRD-GHPLLRSH 1676 Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 R++ L +GSL + ++ ADEGEY C AE+ G + L V Sbjct: 1677 RIQALLNGSLVIYSINAADEGEYQCLAESEAGTAERTITLKV 1718 Score = 87.8 bits (208), Expect = 2e-15 Identities = 66/200 (33%), Positives = 92/200 (46%), Gaps = 14/200 (7%) Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62 D ++ P E P DVT+ + Q L+C A G+P P I W S + L Sbjct: 1533 DSRLSINMRPAFKELPGDVTLNKGQNLALSCHAQGTPPPVISWTVNN----SPQTGATLD 1588 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRN--ATLHVAVLREEFRLEPESKQSA 120 G L S AG Y C A NS G+ R+ + VL+ E R+ S+ Sbjct: 1589 ESGRSSL-IIENVTTSHAGTYVCIAENSVGSIRALSFVRVREPPVLKGEARM---SQTVV 1644 Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180 QG + +L+C P G P P + W ++G LL R+ + G+LVI D G YQC Sbjct: 1645 QGSSAILDC-PIHGDPSPVLQWLRDGHPLL--RSHRIQALLNGSLVIYSINAADEGEYQC 1701 Query: 181 IARNAAGTRESAIATLKIHI 200 +A + AGT E I TLK+ + Sbjct: 1702 LAESEAGTAERTI-TLKVQV 1720 >UniRef50_UPI0000E460A7 Cluster: PREDICTED: similar to OTTHUMP00000065631; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to OTTHUMP00000065631 - Strongylocentrotus purpuratus Length = 3664 Score = 182 bits (442), Expect = 7e-44 Identities = 145/476 (30%), Positives = 219/476 (46%), Gaps = 33/476 (6%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64 YV+ E P I Q ATL+C G P P I W+KG + T+ I P G Sbjct: 791 YVSYHEPPRIQMTQYRYLTPPSQKATLSCPTSGVPPPEITWFKGDRDLTRVTYTRIWPNG 850 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GD 123 L + G SD+G Y C ATN G + T+H+ V L+P G Sbjct: 851 DLDIM----GVQDSDSGSYTCYATNEAGVV---SETVHLEVGSSPIILQPPIDLGVNYGM 903 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183 V + C+ G P P V W+K GQ+ L D + R+ + + GNL I+D + D+G Y C+A Sbjct: 904 NVSVTCIA-MGHPPPAVTWRKVGQSHL-DINPRITMTEDGNLFIRDMQVEDSGTYVCVAH 961 Query: 184 NAAGTRESAIATLKIH--IKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLWRRSAG 240 N G+ E++ A L+I I+P + ++ V V +C V G+P P V W S+ Sbjct: 962 NEHGSTEAS-AQLRITNLIQPQISATSQEEVVVVEDDVVVRCNVISGNPPPTVTWFHSSE 1020 Query: 241 GGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299 R+++ DGSL + +++D G Y+C AEN++G + + V++PPSI+ + Sbjct: 1021 RLYPEYSPRLELFPDGSLGIRGAVMSDAGNYTCVAENAIGNDTKITRIRVHNPPSISGTE 1080 Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359 S V C A G P P + W ++ +TI P + H +A LT++ Sbjct: 1081 TSYTVIHHESVTLLCPAAGHPPPLIEW-IKNGQTI--PNLG---LHQSA-------LTLS 1127 Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419 + D+ T +C N AG S + L + + T G N T PC Sbjct: 1128 YVTEQDA-GTYICRVSNLAGFSEIEITLFILVPPAH-EGVETTGVVNVTQ--GDSVTLPC 1183 Query: 420 TAICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 TP P I+W+ + L + R V DG LV++ + ++ G Y CVAS+ G Sbjct: 1184 NVRGTPPPQISWFKDNLPLPEAGRNFYVNTDGGLVIQQMSVAEEGQYRCVASNIAG 1239 Score = 175 bits (427), Expect = 5e-42 Identities = 125/462 (27%), Positives = 200/462 (43%), Gaps = 28/462 (6%) Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74 +E+ +T+ Q +L C G+P P + WYK G +S T ++ L + Sbjct: 1442 VEETFSITIG--QTVSLPCEVTGTPPPIVTWYKSGN-PISVTSSMVITQDSLDI----YS 1494 Query: 75 RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRG 134 D G+Y C A+N G +RN L + ++ + P ++ + G + LEC G Sbjct: 1495 TRPFDTGIYQCVASNVAGNV-TRNFRL-IVMIPPSIQDGPATRTTEVGAHIELECRAD-G 1551 Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194 P P++ W K+G+ L D R+ G L I + Q D+G Y C N AG + S Sbjct: 1552 IPLPDITWYKDGEPLGTYNDPRLRKTAFGTLQIVNVDQEDSGEYACYVSNDAG-KASKFV 1610 Query: 195 TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254 TL +++ P L+ P+ + + VT QC G P PDV W ++ N R + Sbjct: 1611 TLTVNLAPILLDSPDSYTSLIRNPVTLQCLAAGFPPPDVTWLKNGAPLNQEDVRYYITPS 1670 Query: 255 GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP-SINLSPNSVNVESGNVARFT 313 SL + + + D G Y+C N+ G LTVY PP SIN S +V N Sbjct: 1671 NSLLIASTMREDSGIYTCNVSNTAGHQYKHMELTVYLPPTSINSGDTSYDVTLNNPVSLP 1730 Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373 C P PT+ W +G + P + Y + + + D+ C Sbjct: 1731 CEVQSYPPPTITWLKDGR---VIP-YTNSHYRIQPSSLDIPMAVVRDS------GVYTCI 1780 Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF 433 A N G+ ++ V + PP I+ GP T + PC +I P P+ W Sbjct: 1781 ATNIVGNISRNYQINV-----QVPPYISPGPDTITAYLGQNVTLPCDSIGVPTPMTMWDK 1835 Query: 434 EGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 G L + R + ++G+L++ D+ + D+G Y C+ ++ G Sbjct: 1836 SGLQLNYDDSRFHKLDEGSLIISDVRELDAGAYYCLVVNQAG 1877 Score = 173 bits (421), Expect = 2e-41 Identities = 138/479 (28%), Positives = 199/479 (41%), Gaps = 30/479 (6%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-DTHRSILPAGGLFFLR 70 P I TV H+ TL C A G P P I W K G + + H+S L + Sbjct: 1074 PSISGTETSYTVIHHESVTLLCPAAGHPPPLIEWIKNGQTIPNLGLHQSALTLSYV---- 1129 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLEC 129 DAG Y C +N G + TL + V +E + QGD+V L C Sbjct: 1130 -----TEQDAGTYICRVSNLAGFSEIE-ITLFILVPPAHEGVETTGVVNVTQGDSVTLPC 1183 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189 RG+P P + W K+ L G + DGG LVIQ + G+Y+C+A N AG Sbjct: 1184 -NVRGTPPPQISWFKDNLPLPEAGRNFYVNTDGG-LVIQQMSVAEEGQYRCVASNIAGNV 1241 Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249 + + I + P + G + G S+ C G P+P+V+W++ ++ V Sbjct: 1242 SKDVR-ITILVPPSIEPGNTEYAVVAGGSIILSCEAYGIPMPEVVWQKDGAQLSIATRNV 1300 Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309 ++LD GSL++D G Y+C N G+ + L+V PP I V G Sbjct: 1301 RILDLGSLQIDVTSEEHTGTYTCLVTNEAGSTNRLITLSVIVPPRIFDGQTQYTVVQGQA 1360 Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369 C ATG P PT+ WS EG I P ++ Y + +T+ + TD T Sbjct: 1361 IILHCPATGTPPPTITWSKEG---IAIP-LNDPHYDVDEIAGTLTMFGVLPTD----FGT 1412 Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ-TLPIKSMAVFPCTAICTPEPI 428 C N GS + L+V P+I ++ I PC TP PI Sbjct: 1413 YKCVVRNDGGSVYKDITLSV-----HVAPVIEEAVEETFSITIGQTVSLPCEVTGTPPPI 1467 Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 + WY G + +T D +L + D+G Y CVAS+ G + L+V P Sbjct: 1468 VTWYKSGNPISVTSSMVITQD-SLDIYSTRPFDTGIYQCVASNVAGNVTRNFRLIVMIP 1525 Score = 172 bits (419), Expect = 4e-41 Identities = 140/457 (30%), Positives = 198/457 (43%), Gaps = 32/457 (7%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80 VT Q L C A G P+P I W K G V S ++ + G+ + SDA Sbjct: 3114 VTTQIGQSVRLFCDATGVPTPEILWQKDGQRV-SPMEGFLIISDGMLQINDAQP---SDA 3169 Query: 81 GVYWCEATNSYGTARSRNAT-LHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139 G Y C A N G + +H E E + A +V LEC G P+PN Sbjct: 3170 GRYDCIAKNGAGADVFKVILEVHEPPQIAETTKTYEIRVDA---SVELECRVG-GIPKPN 3225 Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG--TRESAIATLK 197 + W NG+ L G + L +G NL I R D+G Y C+A+N AG E + L Sbjct: 3226 IRWLFNGREL---GAQSLKLANG-NLKIPVVRAEDSGAYTCLAQNDAGFAQAERILVVLD 3281 Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257 + P ++ C G P P+V WR+ G P GR+ + ++ L Sbjct: 3282 VPRLPRPPREQSEMTISVNRRAVLTCPADGYPPPEVTWRKD-GILVEPAGRITMTENHEL 3340 Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317 +D V +D G Y+C A NS+G+ + YLTV P+ PN V + +GN C A Sbjct: 3341 IIDRVQESDSGTYTCVATNSIGSNRLNFYLTVQVAPTFTHFPNDVELAAGNRLELICEAI 3400 Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377 G P P + W V G I P FDG +VL I + K+DS T +C A N Sbjct: 3401 GVPMPDIAWLVNGTEMIPNP----------PTFDGRSVLAIGNVQKSDS-GTYMCRAENI 3449 Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437 G + +T+ R PP I PS+ TL + AV C P+P + W Sbjct: 3450 LGV-----RTAITAVRVRVPPRIHRIPSDTTLTLGERAVLNCAVNGDPKPEVTWLKNNRP 3504 Query: 438 LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 + ++DG+L++ SD+G Y C A + +G Sbjct: 3505 VALTDTMQQSSDGSLIIAPTAISDAGFYKCQALNLYG 3541 Score = 165 bits (400), Expect = 9e-39 Identities = 132/459 (28%), Positives = 188/459 (40%), Gaps = 24/459 (5%) Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77 P+ +++ L C A G P P IRWYK G LV + + G R+H Sbjct: 2833 PMMMSINEDDSTQLGCHASGYPPPTIRWYKDGRLVTHNEPGVAVSNSGEVLRINRVNRIH 2892 Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSP 136 AG + C A++ G S++ L+V V E E P + + L C P P Sbjct: 2893 --AGQFTCVASSIVGNI-SKSYVLNVRVRPEIEGAEFPHNVSVVNNMGIELRC-PTVAIP 2948 Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196 P + W K+G L + DG L I +A+ D G YQC+A N AG E + L Sbjct: 2949 VPEIVWYKDGHRLHPFQSGVLISPDGTTLRIPNAQLHDEGVYQCVATNVAG-EEMKLFNL 3007 Query: 197 KIHIKPYLITG-PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255 +I + P +++ P + G S T C G P P V W ++ + R + G Sbjct: 3008 QIDVPPVIVSREPNQIAVIAGGSTTIDCESYGVPKPTVTWTKNNAFISPASIRYDIDPAG 3067 Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315 L + V +ADEG + C NS G V+ L V P+I V + G R C Sbjct: 3068 LLHIATVTVADEGVFECFVSNSAGNVTRRIDLQVQVQPTITPGRGRVTTQIGQSVRLFCD 3127 Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375 ATG P P + W +G R G + DG +L IND +D+ C A Sbjct: 3128 ATGVPTPEILWQKDGQRVSPMEGF-------LIISDG--MLQINDAQPSDA-GRYDCIAK 3177 Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG 435 N AG+ + L V PP I + + + C P+P I W F G Sbjct: 3178 NGAGADVFKVILEV-----HEPPQIAETTKTYEIRVDASVELECRVGGIPKPNIRWLFNG 3232 Query: 436 EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 L + +G L + + DSG YTC+A + G Sbjct: 3233 RELGAQSLK--LANGNLKIPVVRAEDSGAYTCLAQNDAG 3269 Score = 158 bits (384), Expect = 7e-37 Identities = 147/527 (27%), Positives = 218/527 (41%), Gaps = 35/527 (6%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG--VLVVSDTHRSILPAGGLFFL 69 P I + P T L CRA G P P I WYK G + +D G L + Sbjct: 1526 PSIQDGPATRTTEVGAHIELECRADGIPLPDITWYKDGEPLGTYNDPRLRKTAFGTLQIV 1585 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 D+G Y C +N G A S+ TL V L P+S S + V L+C Sbjct: 1586 NVDQ----EDSGEYACYVSNDAGKA-SKFVTLTVN-LAPILLDSPDSYTSLIRNPVTLQC 1639 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189 L G P P+V W KNG L + D R ++ +L+I + D+G Y C N AG + Sbjct: 1640 LAA-GFPPPDVTWLKNGAPLNQE-DVRYYITPSNSLLIASTMREDSGIYTCNVSNTAGHQ 1697 Query: 190 ESAIATLKIHIKPYLI-TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248 + L +++ P I +G + V+ C V P P + W + G +P Sbjct: 1698 YKHME-LTVYLPPTSINSGDTSYDVTLNNPVSLPCEVQSYPPPTITWLKD--GRVIPYTN 1754 Query: 249 VKV-LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESG 307 + SL + ++ D G Y+C A N VG +S + + V PP I+ P+++ G Sbjct: 1755 SHYRIQPSSLDIPMAVVRDSGVYTCIATNIVGNISRNYQINVQVPPYISPGPDTITAYLG 1814 Query: 308 NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367 C + G P P W G + ++H + +G L I+D + D+ Sbjct: 1815 QNVTLPCDSIGVPTPMTMWDKSGLQL----NYDDSRFHK--LDEGS--LIISDVRELDA- 1865 Query: 368 NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427 C VN AG+ R LTV P II P + + PC A TP P Sbjct: 1866 GAYYCLVVNQAGADTRRITLTVKD----APRIINELPEVMEQIMNTEVRIPCQATGTPRP 1921 Query: 428 IIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 ++W+ +G + Q V D TL++ L D+G Y C A S G S + +D+ Sbjct: 1922 QVSWFKDGRPIEQLRGYTVLGDNTLLISSLQPYDNGRYECRAQSESG--FDSIDVFIDTQ 1979 Query: 488 INPNIHFFRAAD---VSSLPGPPTKPITHNVTDT--SVTLSWSQNNK 529 + P+I D V T + NVTD+ ++W QN + Sbjct: 1980 VRPHIAGENTPDDPVVVFTEEDQTVILECNVTDSHPPAEVTWYQNGQ 2026 Score = 155 bits (377), Expect = 5e-36 Identities = 140/526 (26%), Positives = 235/526 (44%), Gaps = 38/526 (7%) Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74 + P+ V Q L C S PA + WY+ G +++ I G LR + Sbjct: 1991 DDPVVVFTEEDQTVILECNVTDSHPPAEVTWYQNGQAILARADIGIHFETGDTSLRLPYL 2050 Query: 75 RVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133 R DAG Y CEATN G++ R + +HV + R E + Q G ++ + C Sbjct: 2051 RPE-DAGHYHCEATNGQGSSQRHFSLEVHVGPVIRNRRQEQVTVQV--GHSITIHC-EAS 2106 Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193 G P+ + W G + +SR H+ G+L +++ + D+G + CIA+N+AG ++ + Sbjct: 2107 GVPDARILWMF-GDIAISSQNSRYHIASNGSLHLREVQVIDSGVFTCIAKNSAGN-DTRV 2164 Query: 194 ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD 253 + + + P + G D+V SSV C G P P++ W ++ N+ ++ L Sbjct: 2165 VNINVIVPPSINDGTSDIVRTLSSSVILPCESAGVPFPEITWYKNGAPLNLSNPNLEKLF 2224 Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN-SVNVESG--NVA 310 GSLR+ +V D G Y C A N G L ++ PPS L P+ S NV +G Sbjct: 2225 SGSLRIRSVEEEDSGVYRCVAVNQAGHDYKMLTLWIHTPPS--LQPDASRNVSTGVDEKV 2282 Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370 C +G P+P W ++ NR ++ M+ K + DG L I D + D R + Sbjct: 2283 IIPCNISGSPKPQYRW-LKNNRELL---MNYGKME--LLEDG--SLMIRDVESID-RGSY 2333 Query: 371 VCSAVNYAG--SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT---P 425 C A N G S +R +++V P IT + P+ + T P Sbjct: 2334 TCEATNAVGVLSRDIRLEVSVA-------PKITGSKTPVEYPVGQYDSIELQCMVTDAFP 2386 Query: 426 EPIIAWYFEGEALI-QNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483 PII WY E L Q + + G TL + ++ +++G Y C A++ G + S Sbjct: 2387 PPIIKWYKGDETLTGQEEAVTIKDQGITLEIGSVNIANAGEYYCTATNDAG--MASMNWT 2444 Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529 +D + P+I + ++++ + + + T++W ++NK Sbjct: 2445 IDVQVTPSILNGQDEYLTTVQNIDITLLCEAEGNPTPTITWERDNK 2490 Score = 155 bits (377), Expect = 5e-36 Identities = 127/477 (26%), Positives = 201/477 (42%), Gaps = 30/477 (6%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P I E + L CR GG P P IRW G + + +S+ A G + Sbjct: 3193 EPPQIAETTKTYEIRVDASVELECRVGGIPKPNIRWLFNGRELGA---QSLKLANGNLKI 3249 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT-VVLE 128 D+G Y C A N G A++ + + V R +S+ + + VL Sbjct: 3250 PVVRAE---DSGAYTCLAQNDAGFAQAERILVVLDVPRLPRPPREQSEMTISVNRRAVLT 3306 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188 C P G P P V W+K+G +L + R+ + + L+I +++D+G Y C+A N+ G+ Sbjct: 3307 C-PADGYPPPEVTWRKDG--ILVEPAGRITMTENHELIIDRVQESDSGTYTCVATNSIGS 3363 Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248 L + + P P DV G+ + C G P+PD+ W + G + Sbjct: 3364 NRLNFY-LTVQVAPTFTHFPNDVELAAGNRLELICEAIGVPMPDIAWLVN---GTEMIPN 3419 Query: 249 VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESG 307 D S L + NV +D G Y C AEN +G +A + V PP I+ P+ + G Sbjct: 3420 PPTFDGRSVLAIGNVQKSDSGTYMCRAENILGVRTAITAVRVRVPPRIHRIPSDTTLTLG 3479 Query: 308 NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367 A C G P+P + W ++ NR + + + + + I+D Sbjct: 3480 ERAVLNCAVNGDPKPEVTW-LKNNRPVALTDTMQQSSDGSLI---IAPTAISDA------ 3529 Query: 368 NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427 C A+N G V L + S RP ++ P N T+ + C A PEP Sbjct: 3530 GFYKCQALNLYGLDEVSYHLEIQS---RPMFVVE--PQNTTVSHGENVLLDCIAQGEPEP 3584 Query: 428 IIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 + W EG ++ R + + TL + +DSG Y C+A ++ G+ V + L V Sbjct: 3585 SMRWQKEGFRVLPVGRVAILPNNTLKIVAAQLTDSGAYMCLAENQMGRAVMTIHLTV 3641 Score = 152 bits (368), Expect = 6e-35 Identities = 121/461 (26%), Positives = 188/461 (40%), Gaps = 24/461 (5%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 +V+ + + C GSP P RW K ++ + + L G +R D Sbjct: 2273 NVSTGVDEKVIIPCNISGSPKPQYRWLKNNRELLMNYGKMELLEDGSLMIRDVES---ID 2329 Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSPEP 138 G Y CEATN+ G SR+ L V+V + + P Q D++ L+C+ P P Sbjct: 2330 RGSYTCEATNAVGVL-SRDIRLEVSVAPKITGSKTPVEYPVGQYDSIELQCMVTDAFPPP 2388 Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198 + W K +TL ++ G L I +AG Y C A N AG S T+ + Sbjct: 2389 IIKWYKGDETLTGQEEAVTIKDQGITLEIGSVNIANAGEYYCTATNDAGMA-SMNWTIDV 2447 Query: 199 HIKPYLITGPEDVVAQTGS-SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257 + P ++ G ++ + + +T C G+P P + W R + + +DGSL Sbjct: 2448 QVTPSILNGQDEYLTTVQNIDITLLCEAEGNPTPTITWERDNKPLELRDSHYLIGEDGSL 2507 Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317 R+ D G Y C A N++G + +L V PP + V + C A Sbjct: 2508 RITAPQHTDSGGYVCVASNNIGYAIKNFHLVVKIPPKTSTQQEVVTIGLRQSVTLRCQAA 2567 Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377 G P PT+ W + + P +R A ++ LTIN T + DS C A N Sbjct: 2568 GFPAPTISWRKD---NLPIPLSTR----AFSISSNGGSLTINSTREGDS-GIYSCIASNE 2619 Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM----AVFPCTAICTPEPIIAWYF 433 G L + PP I+ N+ ++ + PC P+P +AW F Sbjct: 2620 VGEQ----SLDILLKVQEPPIILGELEVNRMQHVQLVEGDDIELPCPTTGYPKPRVAW-F 2674 Query: 434 EGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 ++ + +DGTLV+ D+G YTC A + G Sbjct: 2675 RDNRILSPPEYKIKDDGTLVIPGAMPFDAGVYTCSAVNEAG 2715 Score = 151 bits (366), Expect = 1e-34 Identities = 143/538 (26%), Positives = 235/538 (43%), Gaps = 42/538 (7%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFFLRATHGRVHSD 79 VT+ Q TL C+A G P+P I W K + + T SI GG + +T D Sbjct: 2552 VTIGLRQSVTLRCQAAGFPAPTISWRKDNLPIPLSTRAFSISSNGGSLTINSTR---EGD 2608 Query: 80 AGVYWCEATNSYGTARSRNATLHVA----VLREEFRLEPESKQSAQGDTVVLECLPPRGS 135 +G+Y C A+N G +S + L V +L E + Q +GD + L C P G Sbjct: 2609 SGIYSCIASNEVGE-QSLDILLKVQEPPIILGELEVNRMQHVQLVEGDDIELPC-PTTGY 2666 Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195 P+P V W ++ + L + D G LVI A DAG Y C A N AG +I Sbjct: 2667 PKPRVAWFRDNRIL---SPPEYKIKDDGTLVIPGAMPFDAGVYTCSAVNEAGNSSISI-N 2722 Query: 196 LKIHIKPYLITG--PEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGNMPLGRVKVL 252 + + + P L+ P D++ + C + P+ ++W++ G +++ Sbjct: 2723 VTVMVPPLLVDAYRPVDIIVILNNPARLYCEIDISIPMASIVWQKD-GISLREDSNIRIS 2781 Query: 253 DDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN----LSPNSVNVESG 307 DG L ++ V + +EG Y+C A N+ G + LTV+ PP ++P +++ Sbjct: 2782 RDGQILEINQVQVNNEGRYTCIATNNAGNATKFFGLTVHVPPIFPDGNPVNPMMMSINED 2841 Query: 308 NVARFTCTATGRPEPTMFWSVEGNR-TIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 + + C A+G P PT+ W +G T PG+ AV + VL IN ++ + Sbjct: 2842 DSTQLGCHASGYPPPTIRWYKDGRLVTHNEPGV--------AVSNSGEVLRINRVNRIHA 2893 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTP 425 C A + G+ K V + RP P N ++ + +M + C + P Sbjct: 2894 -GQFTCVASSIVGNI---SKSYVLNVRVRPEIEGAEFPHNVSV-VNNMGIELRCPTVAIP 2948 Query: 426 EPIIAWYFEGEALIQNHRRN-VTNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483 P I WY +G L ++ DGT L + + D G Y CVA++ G+ + L Sbjct: 2949 VPEIVWYKDGHRLHPFQSGVLISPDGTTLRIPNAQLHDEGVYQCVATNVAGEEMKLFNLQ 3008 Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541 +D P P I ++ + G T + T++W++NN S + + Y ++ Sbjct: 3009 IDVP--PVIVSREPNQIAVIAGGSTTIDCESYGVPKPTVTWTKNNAFISPASIRYDID 3064 Score = 148 bits (359), Expect = 8e-34 Identities = 112/413 (27%), Positives = 179/413 (43%), Gaps = 22/413 (5%) Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140 GVY C A N G+ARS T P + G V+ C + E N+ Sbjct: 592 GVYSCIAENEEGSARSE--TYLDITEPPPVIARPYNTSVLPGSDGVMSCFIS-STVEYNI 648 Query: 141 YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200 W K + G +R+ L++ G+LVIQD DAG Y+C A N G E + L + Sbjct: 649 TWDKPNTLVSLQGHNRVSLMNNGSLVIQDVHPGDAGSYRCRAWNEGGVTEEHV-YLYVQE 707 Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLD 260 +P + +V + ++T +C G P P++ W + G +P+ + ++ Sbjct: 708 RPQINAYQGNVTFTSSQNITLRCSANGYPHPELRWLKD--GQELPIVPGTRRGEIIHQIF 765 Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320 N D+G Y+C A N+ G+ + Y++ ++PP I ++ A +C +G P Sbjct: 766 NASREDQGIYTCLASNTAGSDLLNVYVSYHEPPRIQMTQYRYLTPPSQKATLSCPTSGVP 825 Query: 321 EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGS 380 P + W +G+R ++R Y + ++ + D+D + C A N AG Sbjct: 826 PPEITW-FKGDR-----DLTRVTYTRIWPNGDLDIMGVQDSDS----GSYTCYATNEAGV 875 Query: 381 SFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ 440 L V S PII P + + C A+ P P + W G++ + Sbjct: 876 VSETVHLEVGSS-----PIILQPPIDLGVNYGMNVSVTCIAMGHPPPAVTWRKVGQSHLD 930 Query: 441 -NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492 N R +T DG L ++D+ DSGTY CVA + HG S L + + I P I Sbjct: 931 INPRITMTEDGNLFIRDMQVEDSGTYVCVAHNEHGSTEASAQLRITNLIQPQI 983 Score = 142 bits (345), Expect = 4e-32 Identities = 130/491 (26%), Positives = 204/491 (41%), Gaps = 28/491 (5%) Query: 6 VTSGEAPYIIE--QPLDVTVARHQPATLNCRAGGS-PSPAIRWYKGGVLVVSDTHRSILP 62 VT P +++ +P+D+ V + PA L C S P +I W K G+ + D++ I Sbjct: 2723 VTVMVPPLLVDAYRPVDIIVILNNPARLYCEIDISIPMASIVWQKDGISLREDSNIRISR 2782 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVA-VLREEFRLEPESKQSA 120 G + L +V+++ G Y C ATN+ G A + T+HV + + + P Sbjct: 2783 DGQI--LEINQVQVNNE-GRYTCIATNNAGNATKFFGLTVHVPPIFPDGNPVNPMMMSIN 2839 Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180 + D+ L C G P P + W K+G+ + + G L I + AG++ C Sbjct: 2840 EDDSTQLGC-HASGYPPPTIRWYKDGRLVTHNEPGVAVSNSGEVLRINRVNRIHAGQFTC 2898 Query: 181 IARNAAGTRESAIATLKIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238 +A + G + L + ++P + P +V + +C P+P+++W + Sbjct: 2899 VASSIVGNISKSYV-LNVRVRPEIEGAEFPHNVSVVNNMGIELRCPTVAIPVPEIVWYKD 2957 Query: 239 AGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-N 296 + V + DG+ LR+ N L DEG Y C A N G L + PP I + Sbjct: 2958 GHRLHPFQSGVLISPDGTTLRIPNAQLHDEGVYQCVATNVAGEEMKLFNLQIDVPPVIVS 3017 Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356 PN + V +G C + G P+PT+ W+ N I P R + TV Sbjct: 3018 REPNQIAVIAGGSTTIDCESYGVPKPTVTWTK--NNAFISPASIRYDIDPAGLLHIATV- 3074 Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416 T+ D C N AG+ R L V + P IT G T I Sbjct: 3075 TVAD------EGVFECFVSNSAGNVTRRIDLQV-----QVQPTITPGRGRVTTQIGQSVR 3123 Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476 C A P P I W +G+ + + +DG L + D SD+G Y C+A + G Sbjct: 3124 LFCDATGVPTPEILWQKDGQRVSPMEGFLIISDGMLQINDAQPSDAGRYDCIAKNGAGAD 3183 Query: 477 VWSGALLVDSP 487 V+ L V P Sbjct: 3184 VFKVILEVHEP 3194 Score = 142 bits (344), Expect = 5e-32 Identities = 131/482 (27%), Positives = 194/482 (40%), Gaps = 37/482 (7%) Query: 2 SDDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI- 60 S+ Y+ E P +I +P + +V ++C + I W K LV H + Sbjct: 607 SETYLDITEPPPVIARPYNTSVLPGSDGVMSCFISSTVEYNITWDKPNTLVSLQGHNRVS 666 Query: 61 LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA 120 L G ++ H DAG Y C A N G + L+V R + + Sbjct: 667 LMNNGSLVIQDVH---PGDAGSYRCRAWNE-GGVTEEHVYLYVQE-RPQINAYQGNVTFT 721 Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179 + L C G P P + W K+GQ L + G R ++ I +A + D G Y Sbjct: 722 SSQNITLRC-SANGYPHPELRWLKDGQELPIVPGTRRGEIIH----QIFNASREDQGIYT 776 Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239 C+A N AG+ + + H P + + T C G P P++ W + Sbjct: 777 CLASNTAGS-DLLNVYVSYHEPPRIQMTQYRYLTPPSQKATLSCPTSGVPPPEITWFK-- 833 Query: 240 GGGNMPLGRV---KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296 G+ L RV ++ +G L + V +D G Y+C A N G VS + +L V P I Sbjct: 834 --GDRDLTRVTYTRIWPNGDLDIMGVQDSDSGSYTCYATNEAGVVSETVHLEVGSSPIIL 891 Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI-IFPGMSRDKYHATAVFDGVTV 355 P + V G TC A G P P + W G + I P T DG Sbjct: 892 QPPIDLGVNYGMNVSVTCIAMGHPPPAVTWRKVGQSHLDINP-------RITMTEDG--N 942 Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415 L I D DS T VC A N GS+ +L +T + P I+ + + ++ Sbjct: 943 LFIRDMQVEDS-GTYVCVAHNEHGSTEASAQLRIT---NLIQPQISATSQEEVVVVEDDV 998 Query: 416 VFPCTAIC-TPEPIIAWYFEGEALIQNH--RRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472 V C I P P + W+ E L + R + DG+L ++ SD+G YTCVA + Sbjct: 999 VVRCNVISGNPPPTVTWFHSSERLYPEYSPRLELFPDGSLGIRGAVMSDAGNYTCVAENA 1058 Query: 473 HG 474 G Sbjct: 1059 IG 1060 Score = 142 bits (344), Expect = 5e-32 Identities = 127/481 (26%), Positives = 196/481 (40%), Gaps = 37/481 (7%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAG 64 +T AP +++ P T P TL C A G P P + W K G L D I P+ Sbjct: 1612 LTVNLAPILLDSPDSYTSLIRNPVTLQCLAAGFPPPDVTWLKNGAPLNQEDVRYYITPSN 1671 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124 L + D+G+Y C +N+ G + ++ L V + S + Sbjct: 1672 SLLIAST----MREDSGIYTCNVSNTAGH-QYKHMELTVYLPPTSINSGDTSYDVTLNNP 1726 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 V L C + P P + W K+G+ + + + + +L I A D+G Y CIA N Sbjct: 1727 VSLPC-EVQSYPPPTITWLKDGRVIPYTNSH--YRIQPSSLDIPMAVVRDSGVYTCIATN 1783 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 G S + + + PY+ GP+ + A G +VT C G P P +W +S N Sbjct: 1784 IVGNI-SRNYQINVQVPPYISPGPDTITAYLGQNVTLPCDSIGVPTPMTMWDKSGLQLNY 1842 Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS-INLSPNSVN 303 R LD+GSL + +V D G Y C N GA + LTV D P IN P + Sbjct: 1843 DDSRFHKLDEGSLIISDVRELDAGAYYCLVVNQAGADTRRITLTVKDAPRIINELPEVME 1902 Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363 R C ATG P P + W +G R I ++ V G L I+ Sbjct: 1903 QIMNTEVRIPCQATGTPRPQVSWFKDG-RPI-------EQLRGYTVL-GDNTLLISSLQP 1953 Query: 364 NDSRNTIVCSAVNYAG----SSFVRGKLT--VTSDDDRPPPIITNGPSNQTLPIKSMAVF 417 D+ C A + +G F+ ++ + ++ P++ +QT+ + Sbjct: 1954 YDN-GRYECRAQSESGFDSIDVFIDTQVRPHIAGENTPDDPVVVFTEEDQTV------IL 2006 Query: 418 PCTAICTPEPI-IAWYFEGEALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRH 473 C + P + WY G+A++ + T D +L L L D+G Y C A++ Sbjct: 2007 ECNVTDSHPPAEVTWYQNGQAILARADIGIHFETGDTSLRLPYLRPEDAGHYHCEATNGQ 2066 Query: 474 G 474 G Sbjct: 2067 G 2067 Score = 137 bits (332), Expect = 1e-30 Identities = 128/487 (26%), Positives = 199/487 (40%), Gaps = 36/487 (7%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFLR 70 P I + D+ L C + G P P I WYK G L +S+ + L +G L +R Sbjct: 2173 PSINDGTSDIVRTLSSSVILPCESAGVPFPEITWYKNGAPLNLSNPNLEKLFSGSL-RIR 2231 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GDTVVL 127 + D+GVY C A N G + + + L+P++ ++ + V++ Sbjct: 2232 SVE---EEDSGVYRCVAVNQAG----HDYKMLTLWIHTPPSLQPDASRNVSTGVDEKVII 2284 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 C GSP+P W KN + LL + +M L++ G+L+I+D D G Y C A NA G Sbjct: 2285 PC-NISGSPKPQYRWLKNNRELLMN-YGKMELLEDGSLMIRDVESIDRGSYTCEATNAVG 2342 Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTG--SSVTFQCRV-GGDPLPDVLWRRSAGGGNM 244 I L++ + P + V G S+ QC V P P + W + Sbjct: 2343 VLSRDI-RLEVSVAPKITGSKTPVEYPVGQYDSIELQCMVTDAFPPPIIKWYKGDETLTG 2401 Query: 245 PLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303 V + D G +L + +V +A+ GEY C A N G S + + V PSI + Sbjct: 2402 QEEAVTIKDQGITLEIGSVNIANAGEYYCTATNDAGMASMNWTIDVQVTPSILNGQDEYL 2461 Query: 304 VESGNV-ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362 N+ C A G P PT+ W + P RD ++ + + TD Sbjct: 2462 TTVQNIDITLLCEAEGNPTPTITWERDNK-----PLELRDSHYLIGEDGSLRITAPQHTD 2516 Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422 VC A N G + L V + PP + T+ ++ C A Sbjct: 2517 SGG----YVCVASNNIGYAIKNFHLVV-----KIPPKTSTQQEVVTIGLRQSVTLRCQAA 2567 Query: 423 CTPEPIIAWYFEGEALIQNHR--RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480 P P I+W + + + R +N G+L + + DSG Y+C+AS+ G+ Sbjct: 2568 GFPAPTISWRKDNLPIPLSTRAFSISSNGGSLTINSTREGDSGIYSCIASNEVGEQSLDI 2627 Query: 481 ALLVDSP 487 L V P Sbjct: 2628 LLKVQEP 2634 Score = 134 bits (323), Expect = 2e-29 Identities = 137/487 (28%), Positives = 205/487 (42%), Gaps = 41/487 (8%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFLRATHGRVHSD 79 +T ++ TL C A G+P+P I W + L + D+H I G L R T + H+D Sbjct: 2461 LTTVQNIDITLLCEAEGNPTPTITWERDNKPLELRDSHYLIGEDGSL---RITAPQ-HTD 2516 Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139 +G Y C A+N+ G A +N L V + + + E +V L C G P P Sbjct: 2517 SGGYVCVASNNIGYA-IKNFHL-VVKIPPKTSTQQEVVTIGLRQSVTLRC-QAAGFPAPT 2573 Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199 + W+K+ + + +GG+L I R+ D+G Y CIA N G +S LK+ Sbjct: 2574 ISWRKDNLPIPLSTRAFSISSNGGSLTINSTREGDSGIYSCIASNEVG-EQSLDILLKVQ 2632 Query: 200 IKPYL-----ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254 P + + + V G + C G P P V W R + P K+ DD Sbjct: 2633 EPPIILGELEVNRMQHVQLVEGDDIELPCPTTGYPKPRVAWFRDNRILSPP--EYKIKDD 2690 Query: 255 GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNVESGNVARF 312 G+L + + D G Y+C A N G S S +TV PP + P + V N AR Sbjct: 2691 GTLVIPGAMPFDAGVYTCSAVNEAGNSSISINVTVMVPPLLVDAYRPVDIIVILNNPARL 2750 Query: 313 TCTA-TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371 C P ++ W +G R+ + DG +L IN N + Sbjct: 2751 YCEIDISIPMASIVWQKDGISL-------REDSNIRISRDG-QILEINQVQVN-NEGRYT 2801 Query: 372 CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG----PSNQTLPIKSMAVFPCTAICTPEP 427 C A N AG++ LTV PPI +G P ++ C A P P Sbjct: 2802 CIATNNAGNATKFFGLTV-----HVPPIFPDGNPVNPMMMSINEDDSTQLGCHASGYPPP 2856 Query: 428 IIAWYFEGEALIQNHRR-NVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485 I WY +G + N V+N G L + +++ +G +TCVASS G S + +++ Sbjct: 2857 TIRWYKDGRLVTHNEPGVAVSNSGEVLRINRVNRIHAGQFTCVASSIVGNI--SKSYVLN 2914 Query: 486 SPINPNI 492 + P I Sbjct: 2915 VRVRPEI 2921 Score = 128 bits (308), Expect = 1e-27 Identities = 130/478 (27%), Positives = 199/478 (41%), Gaps = 41/478 (8%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG--VLVVSDTHRSILP 62 Y+ E P I +VT Q TL C A G P P +RW K G + +V T R + Sbjct: 702 YLYVQERPQINAYQGNVTFTSSQNITLRCSANGYPHPELRWLKDGQELPIVPGTRRGEI- 760 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ--SA 120 + D G+Y C A+N TA S ++V+ E R++ + + Sbjct: 761 ------IHQIFNASREDQGIYTCLASN---TAGSDLLNVYVS-YHEPPRIQMTQYRYLTP 810 Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180 L C P G P P + W K + L +R + G+L I + +D+G Y C Sbjct: 811 PSQKATLSC-PTSGVPPPEITWFKGDRDLTRVTYTR--IWPNGDLDIMGVQDSDSGSYTC 867 Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 A N AG S L++ P ++ P D+ G +V+ C G P P V WR+ G Sbjct: 868 YATNEAGV-VSETVHLEVGSSPIILQPPIDLGVNYGMNVSVTCIAMGHPPPAVTWRK-VG 925 Query: 241 GGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PPSIN- 296 ++ + R+ + +DG+L + ++ + D G Y C A N G+ AS L + + P I+ Sbjct: 926 QSHLDINPRITMTEDGNLFIRDMQVEDSGTYVCVAHNEHGSTEASAQLRITNLIQPQISA 985 Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356 S V V +V +G P PT+ W R ++P S DG L Sbjct: 986 TSQEEVVVVEDDVVVRCNVISGNPPPTVTWFHSSER--LYPEYSP---RLELFPDG--SL 1038 Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416 I +D+ N C A N G+ ++ V + PP I+ ++ T+ Sbjct: 1039 GIRGAVMSDAGN-YTCVAENAIGNDTKITRIRVHN-----PPSISGTETSYTVIHHESVT 1092 Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 C A P P+I W G+ I N + L L + + D+GTY C S+ G Sbjct: 1093 LLCPAAGHPPPLIEWIKNGQT-IPNLG---LHQSALTLSYVTEQDAGTYICRVSNLAG 1146 Score = 120 bits (290), Expect = 2e-25 Identities = 88/289 (30%), Positives = 128/289 (44%), Gaps = 20/289 (6%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD----THRSI 60 Y+T AP P DV +A L C A G P P I W G ++ + RS+ Sbjct: 3369 YLTVQVAPTFTHFPNDVELAAGNRLELICEAIGVPMPDIAWLVNGTEMIPNPPTFDGRSV 3428 Query: 61 LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA 120 L G + SD+G Y C A N G R+ + V V R+ P Sbjct: 3429 LAIGNV---------QKSDSGTYMCRAENILG-VRTAITAVRVRVPPRIHRI-PSDTTLT 3477 Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180 G+ VL C G P+P V W KN + + M G+L+I +DAG Y+C Sbjct: 3478 LGERAVLNC-AVNGDPKPEVTWLKNNRPVAL--TDTMQQSSDGSLIIAPTAISDAGFYKC 3534 Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 A N G E + L+I +P + P++ G +V C G+P P + W++ G Sbjct: 3535 QALNLYGLDEVSY-HLEIQSRPMFVVEPQNTTVSHGENVLLDCIAQGEPEPSMRWQKE-G 3592 Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 +P+GRV +L + +L++ L D G Y C AEN +G + +LTV Sbjct: 3593 FRVLPVGRVAILPNNTLKIVAAQLTDSGAYMCLAENQMGRAVMTIHLTV 3641 Score = 105 bits (251), Expect = 1e-20 Identities = 95/382 (24%), Positives = 145/382 (37%), Gaps = 28/382 (7%) Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199 V W + G L DG I+++ G Y CIA N G+ S L I Sbjct: 558 VRWMRRGTPL--DGPIEFSETGSATWTIKNSDSRIEGVYSCIAENEEGSARSE-TYLDIT 614 Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP-LGRVKVLDDGSLR 258 P +I P + GS C + ++ W + ++ RV ++++GSL Sbjct: 615 EPPPVIARPYNTSVLPGSDGVMSCFISSTVEYNITWDKPNTLVSLQGHNRVSLMNNGSLV 674 Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATG 318 + +V D G Y C A N G YL V + P IN +V S C+A G Sbjct: 675 IQDVHPGDAGSYRCRAWNEGGVTEEHVYLYVQERPQINAYQGNVTFTSSQNITLRCSANG 734 Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378 P P + W +G I PG R G + I + + D + C A N A Sbjct: 735 YPHPELRWLKDGQELPIVPGTRR----------GEIIHQIFNASRED-QGIYTCLASNTA 783 Query: 379 GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438 GS + ++ PP I P A C P P I W+ L Sbjct: 784 GSDLLNVYVSY-----HEPPRIQMTQYRYLTPPSQKATLSCPTSGVPPPEITWFKGDRDL 838 Query: 439 IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY-------VWSGALLVDSPINPN 491 + + +G L + + SDSG+YTC A++ G V S +++ PI+ Sbjct: 839 TRVTYTRIWPNGDLDIMGVQDSDSGSYTCYATNEAGVVSETVHLEVGSSPIILQPPIDLG 898 Query: 492 IHFFRAADVSSLP-GPPTKPIT 512 +++ V+ + G P +T Sbjct: 899 VNYGMNVSVTCIAMGHPPPAVT 920 >UniRef50_P97798 Cluster: Neogenin precursor; n=37; Euteleostomi|Rep: Neogenin precursor - Mus musculus (Mouse) Length = 1493 Score = 177 bits (432), Expect = 1e-42 Identities = 192/741 (25%), Positives = 293/741 (39%), Gaps = 86/741 (11%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169 F +EP S +G +V+L C P PN+ WKK+G L + D R L+ G+L I + Sbjct: 66 FLVEPVDTLSVRGSSVILNC-SAYSEPSPNIEWKKDGTFLNLESDDRRQLLPDGSLFISN 124 Query: 170 A-----RQTDAGRYQCIAR-NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223 + D G YQC+A + GT S A L + P + PE G+S C Sbjct: 125 VVHSKHNKPDEGFYQCVATVDNLGTIVSRTAKLTVAGLPRFTSQPEPSSVYVGNSAILNC 184 Query: 224 RVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAENS-VG 279 V D +P V W ++ PL R+ L G+L + N D G Y C E+ Sbjct: 185 EVNADLVPFVRWEQN----RQPLLLDDRIVKLPSGTLVISNATEGDGGLYRCIVESGGPP 240 Query: 280 AVSASGYLTVY-DPPSIN-----LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRT 333 S L V DP I + P+S+ +G A C +G P P + W N Sbjct: 241 KFSDEAELKVLQDPEEIVDLVFLMRPSSMMKVTGQSAVLPCVVSGLPAPVVRWMK--NEE 298 Query: 334 IIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393 ++ S V L I+D ++D+ T C A N + + +LTV Sbjct: 299 VLDTESS-----GRLVLLAGGCLEISDVTEDDA-GTYFCIADNGNKTVEAQAELTV---- 348 Query: 394 DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLV 453 + PP P+N VF C P P + W G+ +I + + + L Sbjct: 349 -QVPPGFLKQPANIYAHESMDIVFECEVTGKPTPTVKWVKNGDVVIPSDNFKIVKEHNLQ 407 Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALL-----VDSPINPNIHFFRA-------ADVS 501 + L KSD G Y C+A + G L+ V P P A A Sbjct: 408 VLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHDVAIPTLPPTSLTSATTDHLAPATTG 467 Query: 502 SLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV 561 LP P + V+ + L+W L Y V +++E + S+ Sbjct: 468 PLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSV-FYTKEGVDRERVENTSQPG- 525 Query: 562 VIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVS 621 + +++L+P Y+F V +N HG SG S S + V G Sbjct: 526 -------EMQVTIQNLMPATVYIFKVMAQNKHG-SGES--SAPLRVETQPEVQLPGP-AP 574 Query: 622 NSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNF--YYLEGLFIYFRPLDNITIEYE 679 N Y + + + + TP+ EI N+ YY+E + D E + Sbjct: 575 NIRAYATSPTS---ITVTWETPLSGN-----GEIQNYKLYYME------KGTDK---EQD 617 Query: 680 MKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIE 739 + HS ++G L+KYT+Y F ++ + K G + +TL DVP P N+ Sbjct: 618 IDVSSHSYTING-----LKKYTEYSFRVVAYNKHGPGVSTQDVAVRTLSDVPSAAPQNLS 672 Query: 740 MFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTN 799 + + N+ ++ + W PP QNG ITGY + + KS V S ++ Sbjct: 673 LEVRNSKSIVIHWQPPSSTTQNGQITGYKIRYR---KASRKSDVTETLVTGTQLSQLIEG 729 Query: 800 LTSGVSYSVQIAAETIIGLGP 820 L G Y+ ++AA T+ G GP Sbjct: 730 LDRGTEYNFRVAALTVNGTGP 750 Score = 160 bits (388), Expect = 2e-37 Identities = 111/333 (33%), Positives = 148/333 (44%), Gaps = 15/333 (4%) Query: 13 YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGLFFLR 70 Y + +P+D R LNC A PSP I W K G + SD R +LP G LF Sbjct: 65 YFLVEPVDTLSVRGSSVILNCSAYSEPSPNIEWKKDGTFLNLESDDRRQLLPDGSLFISN 124 Query: 71 ATHGRVHS-DAGVYWCEAT-NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128 H + + D G Y C AT ++ GT SR A L VA L F +PE G++ +L Sbjct: 125 VVHSKHNKPDEGFYQCVATVDNLGTIVSRTAKLTVAGL-PRFTSQPEPSSVYVGNSAILN 183 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188 C P V W++N Q LL D R+ + G LVI +A + D G Y+CI + Sbjct: 184 C-EVNADLVPFVRWEQNRQPLLLD--DRIVKLPSGTLVISNATEGDGGLYRCIVESGGPP 240 Query: 189 RESAIATLKIHIKPYLITG------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG- 241 + S A LK+ P I P ++ TG S C V G P P V W ++ Sbjct: 241 KFSDEAELKVLQDPEEIVDLVFLMRPSSMMKVTGQSAVLPCVVSGLPAPVVRWMKNEEVL 300 Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301 GR+ +L G L + +V D G Y C A+N V A LTV PP P + Sbjct: 301 DTESSGRLVLLAGGCLEISDVTEDDAGTYFCIADNGNKTVEAQAELTVQVPPGFLKQPAN 360 Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334 + F C TG+P PT+ W G+ I Sbjct: 361 IYAHESMDIVFECEVTGKPTPTVKWVKNGDVVI 393 Score = 139 bits (336), Expect = 5e-31 Identities = 197/844 (23%), Positives = 325/844 (38%), Gaps = 78/844 (9%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 +T P QP +V A LNC P +RW + ++ D LP+G Sbjct: 157 LTVAGLPRFTSQPEPSSVYVGNSAILNCEVNADLVPFVRWEQNRQPLLLDDRIVKLPSGT 216 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-----FRLEPESKQSA 120 L AT G D G+Y C + S A L V EE F + P S Sbjct: 217 LVISNATEG----DGGLYRCIVESGGPPKFSDEAELKVLQDPEEIVDLVFLMRPSSMMKV 272 Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180 G + VL C+ G P P V W KN + L + R+ L+ GG L I D + DAG Y C Sbjct: 273 TGQSAVLPCVVS-GLPAPVVRWMKNEEVLDTESSGRLVLLAGGCLEISDVTEDDAGTYFC 331 Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 IA N T E A A L + + P + P ++ A + F+C V G P P V W ++ G Sbjct: 332 IADNGNKTVE-AQAELTVQVPPGFLKQPANIYAHESMDIVFECEVTGKPTPTVKWVKN-G 389 Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV--YDPPSINLS 298 +P K++ + +L++ ++ +DEG Y C AEN VG A L + +D L Sbjct: 390 DVVIPSDNFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHDVAIPTLP 449 Query: 299 PNSV-NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF--------PGMSRDKYHATAV 349 P S+ + + ++A T + S+ R I P Y Sbjct: 450 PTSLTSATTDHLAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYT 509 Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF-VRGKLTVTSDDDRPPPIITNGPSNQT 408 +GV + +T + + + + F V + S + P + P Q Sbjct: 510 KEGVDRERVENTSQPGEMQVTIQNLMPATVYIFKVMAQNKHGSGESSAPLRVETQPEVQ- 568 Query: 409 LP-----IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSG 463 LP I++ A P + T E ++ G IQN++ GT +D+D S S Sbjct: 569 LPGPAPNIRAYATSPTSITVTWETPLS----GNGEIQNYKLYYMEKGTDKEQDIDVS-SH 623 Query: 464 TYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAA--DVSSLPGPPTKPITHNVTDT-SV 520 +YT ++ +Y S ++ + P + A +S +P + ++ V ++ S+ Sbjct: 624 SYTINGLKKYTEY--SFRVVAYNKHGPGVSTQDVAVRTLSDVPSAAPQNLSLEVRNSKSI 681 Query: 521 TLSWS-QNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIP 579 + W ++ + I GY++ + + + + T G Q +++ L Sbjct: 682 VIHWQPPSSTTQNGQITGYKIR-YRKASRKSDVTETLVTG--------TQLSQLIEGLDR 732 Query: 580 GITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELI 639 G Y F V ++G P +D ++ + L E + L IV + Sbjct: 733 GTEYNFRVAALT---VNGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIV--V 787 Query: 640 EATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSN-DVSGFEITSLR 698 TP +++ I + Y G I I ++Y+ + N D S + +L+ Sbjct: 788 SWTPPENQNIVVRG------YAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLK 841 Query: 699 KYTKYEFFLIPFYKKFEGKPSNSR-------VAQTLDDVPDG----PPINIEMFILNTTT 747 + IP Y+ +P + VPD PP+ ++ IL+ T Sbjct: 842 AFNNVGEG-IPLYESAVTRPHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSHDT 900 Query: 748 VHLKWSPPELQLQNGIITGYNVVVNW-LDVPANKSMVAINTTVHQATSLIMTNLTSGVSY 806 + + W+ L I V W ++PAN N T S ++T L Y Sbjct: 901 IRITWADNSLPKHQKITDSRYYTVRWKTNIPANTKYKNANAT---TLSYLVTGLKPNTLY 957 Query: 807 SVQI 810 + Sbjct: 958 EFSV 961 Score = 82.2 bits (194), Expect = 8e-14 Identities = 82/317 (25%), Positives = 130/317 (41%), Gaps = 20/317 (6%) Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241 A + R+S A+++ Y + P D ++ GSSV C +P P++ W++ Sbjct: 44 ATKSGPRRQSQGASVRTFTPFYFLVEPVDTLSVRGSSVILNCSAYSEPSPNIEWKKDGTF 103 Query: 242 GNMPL-GRVKVLDDGSLRLDNVILA-----DEGEYSCEA--ENSVGAVSASGYLTVYDPP 293 N+ R ++L DGSL + NV+ + DEG Y C A +N VS + LTV P Sbjct: 104 LNLESDDRRQLLPDGSLFISNVVHSKHNKPDEGFYQCVATVDNLGTIVSRTAKLTVAGLP 163 Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353 P +V GN A C P + W E NR P + D+ + G Sbjct: 164 RFTSQPEPSSVYVGNSAILNCEVNADLVPFVRW--EQNRQ---PLLLDDR--IVKLPSGT 216 Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIK 412 V++ N T+ + + + S +L V D + ++ PS+ Sbjct: 217 LVIS-NATEGDGGLYRCIVESGGPPKFS-DEAELKVLQDPEEIVDLVFLMRPSSMMKVTG 274 Query: 413 SMAVFPCTAICTPEPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470 AV PC P P++ W E L + R + G L + D+ + D+GTY C+A Sbjct: 275 QSAVLPCVVSGLPAPVVRWMKNEEVLDTESSGRLVLLAGGCLEISDVTEDDAGTYFCIAD 334 Query: 471 SRHGKYVWSGALLVDSP 487 + + L V P Sbjct: 335 NGNKTVEAQAELTVQVP 351 Score = 46.0 bits (104), Expect = 0.006 Identities = 38/136 (27%), Positives = 57/136 (41%), Gaps = 5/136 (3%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILN--TTTVHLK 751 +T L+ T YEF ++ + S + T + VP PP ++ + T+ + Sbjct: 948 VTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGATFELVPTSPPKDVTVVSKEGKPRTIIVN 1007 Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811 W PP NG ITGY ++ DV A I V + + LT Y +I Sbjct: 1008 WQPPSEA--NGKITGY-IIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQ 1064 Query: 812 AETIIGLGPFSQKVYF 827 A G+GP S+ V F Sbjct: 1065 ARNSKGMGPMSEAVQF 1080 >UniRef50_UPI0000D9D2C3 Cluster: PREDICTED: similar to peroxidasin; n=1; Macaca mulatta|Rep: PREDICTED: similar to peroxidasin - Macaca mulatta Length = 754 Score = 177 bits (430), Expect = 2e-42 Identities = 111/351 (31%), Positives = 173/351 (49%), Gaps = 22/351 (6%) Query: 142 WKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH-- 199 W L DSR++L+D G L+IQ+ ++TD G YQC+A+N AG ++ TL+ Sbjct: 365 WGWVSNELSMKTDSRLNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGS 424 Query: 200 -IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---RVKVLDDG 255 +P + P++ G SVT +C G P P + W R G PL RV + G Sbjct: 425 PARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTR---GDRTPLPVDPRVNITPSG 481 Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315 L + NV+ D GEY+C A NS+ +V A+ ++ V P ++P V G F C Sbjct: 482 GLYIQNVVQEDSGEYACSATNSIDSVHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCE 541 Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375 A G P P + W+ G++ +S D+ H V T L I+ +D + C AV Sbjct: 542 AKGNPPPVIAWTKGGSQ------LSVDRRH--LVLSSGT-LRISGVALHD-QGQYECQAV 591 Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG 435 N GS V LTV R P+ + PS+ T+ + + PC++ PEP I W +G Sbjct: 592 NIIGSQKVVAHLTV---QPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDG 648 Query: 436 EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486 + ++ + +++ +G L + D+ +D+G Y CVA + G S L V++ Sbjct: 649 VQVTESGKFHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVLSVNA 699 Score = 152 bits (369), Expect = 5e-35 Identities = 105/352 (29%), Positives = 166/352 (47%), Gaps = 24/352 (6%) Query: 45 WYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV- 103 W + + +D+ ++L G L +D G+Y C A N G +++ TL Sbjct: 367 WVSNELSMKTDSRLNLLDDGTLMIQNTQE----TDQGIYQCMAKNVAGEVKTQEVTLRYF 422 Query: 104 -AVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG 162 + R F ++P++ + G++V LEC G P P + W + +T L D R+++ Sbjct: 423 GSPARPTFVIQPQNTEVLVGESVTLEC-SATGHPPPRISWTRGDRTPL-PVDPRVNITPS 480 Query: 163 GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQ 222 G L IQ+ Q D+G Y C A N+ + A A + + P P+D V G +V FQ Sbjct: 481 GGLYIQNVVQEDSGEYACSATNSIDS-VHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQ 539 Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGRVK-VLDDGSLRLDNVILADEGEYSCEAENSVGAV 281 C G+P P + W + GG + + R VL G+LR+ V L D+G+Y C+A N +G+ Sbjct: 540 CEAKGNPPPVIAWTK--GGSQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQ 597 Query: 282 SASGYLTVYD--PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGM 339 +LTV P P+ VE G + C++ G PEP + W+ +G + Sbjct: 598 KVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQV-----T 652 Query: 340 SRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTS 391 K+H + +G LTIND D+ C A N GS+ V L+V + Sbjct: 653 ESGKFHISP--EG--FLTINDVGPADA-GRYECVARNTIGSASVSMVLSVNA 699 Score = 137 bits (332), Expect = 1e-30 Identities = 91/288 (31%), Positives = 137/288 (47%), Gaps = 14/288 (4%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPA 63 Y S P + QP + V + TL C A G P P I W +G + D +I P+ Sbjct: 421 YFGSPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPS 480 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123 GGL+ V D+G Y C ATNS + + A + V L +F + P+ + +G Sbjct: 481 GGLYIQNV----VQEDSGEYACSATNSIDSVHA-TAFIIVQAL-PQFTVTPQDRVVIEGQ 534 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIA 182 TV +C +G+P P + W K G L D R HLV G L I D G+Y+C A Sbjct: 535 TVDFQC-EAKGNPPPVIAWTKGGSQLSVD---RRHLVLSSGTLRISGVALHDQGQYECQA 590 Query: 183 RNAAGTRE-SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241 N G+++ A T++ + P + P D + G++V C G+P P + W + G Sbjct: 591 VNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKD-GV 649 Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 G+ + +G L +++V AD G Y C A N++G+ S S L+V Sbjct: 650 QVTESGKFHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVLSV 697 Score = 90.6 bits (215), Expect = 2e-16 Identities = 64/200 (32%), Positives = 86/200 (43%), Gaps = 16/200 (8%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P P D V Q C A G+P P I W KGG + D +L +G L R Sbjct: 519 PQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSGTL---RI 575 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEPESKQSAQGDTVVLE 128 + +H D G Y C+A N G S+ H+ V + F P G V L Sbjct: 576 SGVALH-DQGQYECQAVNIIG---SQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLP 631 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188 C +G PEP + W K+G + G + H+ G L I D DAGRY+C+ARN G Sbjct: 632 C-SSQGEPEPAITWNKDGVQVTESG--KFHISPEGFLTINDVGPADAGRYECVARNTIG- 687 Query: 189 RESAIATLKIHIKPYLITGP 208 SA ++ + + L P Sbjct: 688 --SASVSMVLSVNARLFASP 705 Score = 79.4 bits (187), Expect = 6e-13 Identities = 68/247 (27%), Positives = 99/247 (40%), Gaps = 18/247 (7%) Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY--DP--PSINLSPNSVN 303 R+ +LDDG+L + N D+G Y C A+N G V Y P P+ + P + Sbjct: 379 RLNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTE 438 Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363 V G C+ATG P P + W+ G+RT + P R + G+ + + D Sbjct: 439 VLVGESVTLECSATGHPPPRISWT-RGDRTPL-PVDPRVNITPSG---GLYIQNVVQEDS 493 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423 + CSA N S + V + P T P ++ + F C A Sbjct: 494 GE----YACSATNSIDSVHATAFIIVQA-----LPQFTVTPQDRVVIEGQTVDFQCEAKG 544 Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483 P P+IAW G L + R V + GTL + + D G Y C A + G L Sbjct: 545 NPPPVIAWTKGGSQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLT 604 Query: 484 VDSPINP 490 V + P Sbjct: 605 VQPRVTP 611 >UniRef50_A7S5L2 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 298 Score = 175 bits (427), Expect = 5e-42 Identities = 111/294 (37%), Positives = 157/294 (53%), Gaps = 15/294 (5%) Query: 6 VTSGE-APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG--VLVVSDTHRSILP 62 VTS + AP+ +E+P D+ V +++ A L CRAGG PSP I W G + + D R ILP Sbjct: 10 VTSSQLAPFFLEEPSDIVVKKNRQALLKCRAGGLPSPRISWRHNGNDLNLAGDKRRKILP 69 Query: 63 AGGLFFLRATHGRVHS-DAGVYWCEATNSYGTA----RSRNATLHVAVLREEFRLEPESK 117 G L F+ H + D G Y C A++ RSR L VA +F + P S+ Sbjct: 70 DGSLLFITIEHTKSSKPDEGNYQCVASSQVNNLDYEIRSRIVKLQVAG-EADFVVTPPSR 128 Query: 118 QSA-QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAG 176 A +G VLEC +GSP+P V W KNGQ + +D SR+ ++ NL I +DAG Sbjct: 129 VVAIKGKHTVLECAV-KGSPKPVVKWYKNGQIVTYD--SRVTIIGESNLEIMQVVPSDAG 185 Query: 177 RYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 Y+C A ++ SA LK++ P I D A TGS VTF C G+P P+V W Sbjct: 186 TYKCEATSSGSQPVSAETRLKVNYPPVFIKRLRDHNAYTGSVVTFNCTADGNPKPNVYW- 244 Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290 S G + + DG L++++++ +D G Y C A NS+G++ AS L+VY Sbjct: 245 -SKNGYKIGSTDFTKVGDGFLKVEDLLPSDMGMYQCFATNSLGSIQASAELSVY 297 Score = 108 bits (259), Expect = 1e-21 Identities = 72/243 (29%), Positives = 110/243 (45%), Gaps = 13/243 (5%) Query: 99 ATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH 158 +T+ + L F EP + +L+C G P P + W+ NG L GD R Sbjct: 8 STVTSSQLAPFFLEEPSDIVVKKNRQALLKCRAG-GLPSPRISWRHNGNDLNLAGDKRRK 66 Query: 159 LVDGGNLVIQDARQT-----DAGRYQCIARNAAGTRESAIAT--LKIHIK---PYLITGP 208 ++ G+L+ T D G YQC+A + + I + +K+ + +++T P Sbjct: 67 ILPDGSLLFITIEHTKSSKPDEGNYQCVASSQVNNLDYEIRSRIVKLQVAGEADFVVTPP 126 Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268 VVA G +C V G P P V W ++ RV ++ + +L + V+ +D G Sbjct: 127 SRVVAIKGKHTVLECAVKGSPKPVVKWYKNGQIVTYD-SRVTIIGESNLEIMQVVPSDAG 185 Query: 269 EYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327 Y CEA +S VSA L V PP N +G+V F CTA G P+P ++WS Sbjct: 186 TYKCEATSSGSQPVSAETRLKVNYPPVFIKRLRDHNAYTGSVVTFNCTADGNPKPNVYWS 245 Query: 328 VEG 330 G Sbjct: 246 KNG 248 Score = 77.4 bits (182), Expect = 2e-12 Identities = 79/297 (26%), Positives = 116/297 (39%), Gaps = 27/297 (9%) Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLR 258 + P+ + P D+V + +CR GG P P + WR + N+ R K+L DGSL Sbjct: 15 LAPFFLEEPSDIVVKKNRQALLKCRAGGLPSPRISWRHNGNDLNLAGDKRRKILPDGSLL 74 Query: 259 LDNV-----ILADEGEYSCEAENSVGAV-----SASGYLTVYDPPSINLSPNS-VNVESG 307 + DEG Y C A + V + S L V ++P S V G Sbjct: 75 FITIEHTKSSKPDEGNYQCVASSQVNNLDYEIRSRIVKLQVAGEADFVVTPPSRVVAIKG 134 Query: 308 NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367 C G P+P + W G I+ Y + G + L I +D+ Sbjct: 135 KHTVLECAVKGSPKPVVKWYKNGQ--IV-------TYDSRVTIIGESNLEIMQVVPSDA- 184 Query: 368 NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427 T C A + +GS V + + + PP+ + S+ F CTA P+P Sbjct: 185 GTYKCEATS-SGSQPVSAETRLKVNY---PPVFIKRLRDHNAYTGSVVTFNCTADGNPKP 240 Query: 428 IIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 + W G + V DG L ++DL SD G Y C A++ G S L V Sbjct: 241 NVYWSKNGYKIGSTDFTKV-GDGFLKVEDLLPSDMGMYQCFATNSLGSIQASAELSV 296 Score = 61.3 bits (142), Expect = 2e-07 Identities = 61/245 (24%), Positives = 102/245 (41%), Gaps = 23/245 (9%) Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358 P+ + V+ A C A G P P + W GN ++ DK + +TI Sbjct: 23 PSDIVVKKNRQALLKCRAGGLPSPRISWRHNGNDL----NLAGDKRRKILPDGSLLFITI 78 Query: 359 NDT--DKNDSRN--TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414 T K D N + S VN +R ++ ++T P ++ + IK Sbjct: 79 EHTKSSKPDEGNYQCVASSQVNNLDYE-IRSRIVKLQVAGEADFVVT--PPSRVVAIKGK 135 Query: 415 -AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473 V C +P+P++ WY G+ + + R + + L + + SD+GTY C A+S Sbjct: 136 HTVLECAVKGSPKPVVKWYKNGQIVTYDSRVTIIGESNLEIMQVVPSDAGTYKCEATSSG 195 Query: 474 GKYVWSGALLVDSPIN-PNIHFFRAADVSSLPGPPTKPITHNVT---DTSVTLSWSQNN- 528 + V + L +N P + R D ++ G +T N T + + WS+N Sbjct: 196 SQPVSAETRL---KVNYPPVFIKRLRDHNAYTG---SVVTFNCTADGNPKPNVYWSKNGY 249 Query: 529 KIGSS 533 KIGS+ Sbjct: 250 KIGST 254 >UniRef50_UPI0000F2BDAE Cluster: PREDICTED: similar to hCG1996527,; n=1; Monodelphis domestica|Rep: PREDICTED: similar to hCG1996527, - Monodelphis domestica Length = 732 Score = 174 bits (423), Expect = 1e-41 Identities = 127/406 (31%), Positives = 186/406 (45%), Gaps = 29/406 (7%) Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67 +G +++P DV R P L C+ G P +I W + G + + + +++P G L Sbjct: 55 TGSELAFVQEPGDVVALREHPLLLRCQVEGEPPISISWQRDGTPLGNSSGATLMPDGSLH 114 Query: 68 F-----LRATHGRVHSDAGV--YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA 120 RA G + A V Y C A N YG SR A + +A L F PES Sbjct: 115 LGGFPTHRALQGSLLPPASVHEYNCVAQNRYGRLVSRRARVQLASL-SRFHQHPESMVVE 173 Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180 QG +CL RG PEP + W+ N +T L R L+ G L I + Q+D G Y+C Sbjct: 174 QGGVARFQCL-IRGVPEPTISWEHN-RTALSAAHHRFTLLPAGILQITNVGQSDVGTYRC 231 Query: 181 IARNAAGTRESAIATLKIHIK-------PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233 +ARN A TR S A L + K P +++GP+++ + +C G P P V Sbjct: 232 VARNVANTRYSQEAQLALSGKDDRALKEPEILSGPQNLTLTVHQTAVLECIATGHPRPLV 291 Query: 234 LWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV--SASGYLTVYD 291 W R G ++ + ++VL G+L + +V + G Y C A V +A G L V Sbjct: 292 SWSR-LDGRSIGVEGIQVLGTGNLMISDVSVQHSGVYVCAANRPGTRVRRTAQGVLLVQA 350 Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 PP P SV+ G+ A FTC A G PEP + W G ++ PG + H + Sbjct: 351 PPEFVQWPQSVSKPPGSSAIFTCVAQGVPEPRLIWLKNGK--VLSPGENVRLTH-----N 403 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397 T++ T +++ C A N AGS+ +L VT + PP Sbjct: 404 NSTLMLAGVTPADEA--IYQCVAENSAGSNQASARLAVTGAPEPPP 447 Score = 113 bits (271), Expect = 4e-23 Identities = 134/535 (25%), Positives = 204/535 (38%), Gaps = 57/535 (10%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL------LFDGDSRMHLVDGG 163 F EP + + ++L C G P ++ W+++G L D +HL GG Sbjct: 61 FVQEPGDVVALREHPLLLRC-QVEGEPPISISWQRDGTPLGNSSGATLMPDGSLHL--GG 117 Query: 164 ---NLVIQDARQTDAG--RYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSS 218 + +Q + A Y C+A+N G S A +++ PE +V + G Sbjct: 118 FPTHRALQGSLLPPASVHEYNCVAQNRYGRLVSRRARVQLASLSRFHQHPESMVVEQGGV 177 Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSV 278 FQC + G P P + W + + R +L G L++ NV +D G Y C A N Sbjct: 178 ARFQCLIRGVPEPTISWEHNRTALSAAHHRFTLLPAGILQITNVGQSDVGTYRCVARNVA 237 Query: 279 GA-VSASGYLTV-------YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330 S L + P I P ++ + A C ATG P P + WS Sbjct: 238 NTRYSQEAQLALSGKDDRALKEPEILSGPQNLTLTVHQTAVLECIATGHPRPLVSWSRLD 297 Query: 331 NRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT 390 R+I G+ G L I+D S VC+A N G+ R V Sbjct: 298 GRSIGVEGIQ---------VLGTGNLMISDVSVQHS-GVYVCAA-NRPGTRVRRTAQGVL 346 Query: 391 SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT-ND 449 + PP P + + P S A+F C A PEP + W G+ L +T N+ Sbjct: 347 L--VQAPPEFVQWPQSVSKPPGSSAIFTCVAQGVPEPRLIWLKNGKVLSPGENVRLTHNN 404 Query: 450 GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTK 509 TL+L + +D Y CVA + G S L V P P P Sbjct: 405 STLMLAGVTPADEAIYQCVAENSAGSNQASARLAVTGAPEP-------------PPAPQG 451 Query: 510 PITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQ 569 ++ ++V +SW SI+GY + L P +++ + Sbjct: 452 LQAAALSASAVRVSWEPPPARDKPSIIGYVL------LLQPEGEPPGREVQEAVSKGTFE 505 Query: 570 THYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNST 624 +V +L P TY +R ++ G S SP T+G+ +L T V N+T Sbjct: 506 --HVFTNLDPATTYSVRLRAYSAEGASHDSPPVHITTMGNAPAALGFSTKVLNAT 558 >UniRef50_UPI0000DA21B5 Cluster: PREDICTED: similar to hemicentin 1; n=1; Rattus norvegicus|Rep: PREDICTED: similar to hemicentin 1 - Rattus norvegicus Length = 2765 Score = 170 bits (414), Expect = 2e-40 Identities = 139/481 (28%), Positives = 215/481 (44%), Gaps = 37/481 (7%) Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFFLRATHG 74 + PL VTV + ATL+C A GSP+P + W K ++ T+R +L +G L ++ G Sbjct: 889 DAPLRVTVKAGEEATLDCEAQGSPTPLVTWTKDAHPLLPVTNRYELLSSGSLRLVQTQVG 948 Query: 75 RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRG 134 D+G+Y C A+N G A R L V V + + P + G+ + L C+ G Sbjct: 949 ----DSGLYECTASNPAG-ATFRRYILGVQV-PPQVQPGPRVLKVLAGEALDLNCVA-EG 1001 Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194 +P+P + W K+G L+ +G G++ + +D G Y C A +++GT + Sbjct: 1002 NPQPQLNWFKDGMVLMGEGPP-------GSVHFAAVKTSDTGLYHCEASSSSGTDTWKLE 1054 Query: 195 TLKIHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR--VKV 251 + + + D++ + G + + C G P P + WRR + GR V V Sbjct: 1055 LQVLEPPHWGVNETNDLLERVVGENASLLCPAQGSPKPRITWRRVPSSEALN-GRPDVAV 1113 Query: 252 LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE--SGNV 309 L++GSL L +V LAD GEY C+A N VG+ S L VY PPSI + N+ +G Sbjct: 1114 LNEGSLFLSSVSLADSGEYECQATNEVGSASRRVKLVVYVPPSIREEGRTANMSGLAGQP 1173 Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369 C A+G P P + W +G + P S ++ DG L +N S Sbjct: 1174 LTLECDASGFPVPEVVWLKDGQQ---IPEASAHRF-----LDGARSLHFPRIQENHS-GL 1224 Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPI 428 C A N AG + L V PP ++ G + + L + V C P P Sbjct: 1225 YSCQAENQAGRAQRDFNLAVFI----PPSLLGAGAAQEVLGLAGADVKLECQTSGVPTPQ 1280 Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDK--SDSGTYTCVASSRHGKYVWSGALLVDS 486 + W +G+ L+ + + VL+ + D G Y CVA S G+ L + S Sbjct: 1281 VEWIKDGQPLLPGDSHILLQEDGQVLRIISSHLGDEGRYQCVAFSPAGQQAKDFQLSIHS 1340 Query: 487 P 487 P Sbjct: 1341 P 1341 Score = 161 bits (390), Expect = 1e-37 Identities = 146/514 (28%), Positives = 206/514 (40%), Gaps = 44/514 (8%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL---PAGG 65 G AP + + P DVTV + L CRA G P P + W +G + RS +G Sbjct: 689 GYAPRLTDPPQDVTVELGKSVFLTCRATGRPPPTVTWRRGDGQALEPGRRSRTGQRDSGV 748 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 L F R + D Y CEA N +G A++ + + + +G V Sbjct: 749 LVFERVSL----EDQAPYVCEARNVFGKAQAEAQLVVTGHAPPQIASSASVVRVLEGQPV 804 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 L C+ G P P W K G+ L G+ DG +L + A Q DAGRY C+A N Sbjct: 805 SLTCVILAGRPLPERRWLKAGRPLP-PGNRHAVRADG-SLHLDRALQEDAGRYSCVATNV 862 Query: 186 AGTRESAIATLKIHIKPYL-------ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238 AG++ + L + KP + P V + G T C G P P V W + Sbjct: 863 AGSQHRDVE-LVVQAKPRIKINDSQATDAPLRVTVKAGEEATLDCEAQGSPTPLVTWTKD 921 Query: 239 AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298 A R ++L GSLRL + D G Y C A N GA L V PP + Sbjct: 922 AHPLLPVTNRYELLSSGSLRLVQTQVGDSGLYECTASNPAGATFRRYILGVQVPPQVQPG 981 Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358 P + V +G C A G P+P + W +G ++ H AV Sbjct: 982 PRVLKVLAGEALDLNCVAEGNPQPQLNWFKDG--MVLMGEGPPGSVHFAAV--------- 1030 Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP--IKSMAV 416 K C A + +G+ + +L V PP +N L + A Sbjct: 1031 ----KTSDTGLYHCEASSSSGTDTWKLELQVLE-----PPHWGVNETNDLLERVVGENAS 1081 Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVT--NDGTLVLKDLDKSDSGTYTCVASSRHG 474 C A +P+P I W + N R +V N+G+L L + +DSG Y C A++ G Sbjct: 1082 LLCPAQGSPKPRITWRRVPSSEALNGRPDVAVLNEGSLFLSSVSLADSGEYECQATNEVG 1141 Query: 475 KYVWSGALLVDSPINPNI-HFFRAADVSSLPGPP 507 L+V P P+I R A++S L G P Sbjct: 1142 SASRRVKLVVYVP--PSIREEGRTANMSGLAGQP 1173 Score = 156 bits (379), Expect = 3e-36 Identities = 145/500 (29%), Positives = 209/500 (41%), Gaps = 26/500 (5%) Query: 2 SDDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL 61 S V + P ++ P +VTV+ + A L+C+ G + W + + T R + Sbjct: 414 SAQIVITDPPPQLVPGP-NVTVSPGETAILSCQVLGETPYNLTWVRDWRALPVKTGR-VS 471 Query: 62 PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEPESKQS 119 L V SD G Y C A+N G R+ L +RE + + S++ Sbjct: 472 QLRDLSL--EVSSVVPSDGGQYQCVASNPNGLTRASTWLL----VREPPQVSINARSQRF 525 Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179 +QG V + C G P+P+V W + G L DSR+H+ G L+IQ DAG Y Sbjct: 526 SQGVEVRVSC-SASGYPKPHVSWSREG--LALPEDSRIHVDAQGTLIIQGVAPEDAGNYS 582 Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239 C A N GT E + TL P + V+ G C G P P V+W R Sbjct: 583 CQAANEVGTDEETV-TLYYTDPPSVSAINAVVLTAVGEEAVLLCAASGVPPPRVIWYR-- 639 Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299 GG + + G+LR+ D G Y+C+A N +G SA L V P + P Sbjct: 640 -GGLEVILAPEGSRSGTLRIPEAQERDAGLYTCKAVNELGDASAEIQLLVGYAPRLTDPP 698 Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359 V VE G TC ATGRP PT+ W G+ + PG + T D VL Sbjct: 699 QDVTVELGKSVFLTCRATGRPPPTVTWR-RGDGQALEPG----RRSRTGQRDS-GVLVFE 752 Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419 D + VC A N G + +L VT PP I ++ + L + +++ Sbjct: 753 RVSLED-QAPYVCEARNVFGKAQAEAQLVVTG--HAPPQIASSASVVRVLEGQPVSLTCV 809 Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479 P P W G L +R V DG+L L + D+G Y+CVA++ G Sbjct: 810 ILAGRPLPERRWLKAGRPLPPGNRHAVRADGSLHLDRALQEDAGRYSCVATNVAGSQHRD 869 Query: 480 GALLVDSPINPNIHFFRAAD 499 L+V + I+ +A D Sbjct: 870 VELVVQAKPRIKINDSQATD 889 Score = 155 bits (377), Expect = 5e-36 Identities = 139/457 (30%), Positives = 185/457 (40%), Gaps = 40/457 (8%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 ++C A G P P + W + G+ + D+ + G L G DAG Y C+A N Sbjct: 533 VSCSASGYPKPHVSWSREGLALPEDSRIHVDAQGTLII----QGVAPEDAGNYSCQAANE 588 Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG-QTL 149 GT TL+ + +A G+ VL C G P P V W + G + + Sbjct: 589 VGTDEE-TVTLYYTDPPSVSAINAVVL-TAVGEEAVLLCAAS-GVPPPRVIWYRGGLEVI 645 Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209 L SR G L I +A++ DAG Y C A N G + I L + P L P+ Sbjct: 646 LAPEGSR-----SGTLRIPEAQERDAGLYTCKAVNELGDASAEIQLL-VGYAPRLTDPPQ 699 Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDGSLRLDNVILADE 267 DV + G SV CR G P P V WRR G P R + D G L + V L D+ Sbjct: 700 DVTVELGKSVFLTCRATGRPPPTVTWRRGDGQALEPGRRSRTGQRDSGVLVFERVSLEDQ 759 Query: 268 GEYSCEAENSVGAVSASGYLTV--YDPPSINLSPNSVNVESGNVARFTCTA-TGRPEPTM 324 Y CEA N G A L V + PP I S + V V G TC GRP P Sbjct: 760 APYVCEARNVFGKAQAEAQLVVTGHAPPQIASSASVVRVLEGQPVSLTCVILAGRPLPER 819 Query: 325 FWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF-- 382 W G + PG HA DG L D + C A N AGS Sbjct: 820 RWLKAGRP--LPPG----NRHAVRA-DGSLHL---DRALQEDAGRYSCVATNVAGSQHRD 869 Query: 383 ----VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438 V+ K + +D + T+ P T+ A C A +P P++ W + L Sbjct: 870 VELVVQAKPRIKINDSQA----TDAPLRVTVKAGEEATLDCEAQGSPTPLVTWTKDAHPL 925 Query: 439 IQ-NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 + +R + + G+L L DSG Y C AS+ G Sbjct: 926 LPVTNRYELLSSGSLRLVQTQVGDSGLYECTASNPAG 962 Score = 142 bits (343), Expect = 7e-32 Identities = 127/474 (26%), Positives = 204/474 (43%), Gaps = 39/474 (8%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P + P + V + LNC A G+P P + W+K G++++ + P G + F Sbjct: 976 PQVQPGPRVLKVLAGEALDLNCVAEGNPQPQLNWFKDGMVLMGEG-----PPGSVHFAAV 1030 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK---QSAQGDTVVLE 128 SD G+Y CEA++S GT + L + VL E+ + G+ L Sbjct: 1031 K----TSDTGLYHCEASSSSGTDTWK---LELQVLEPPHWGVNETNDLLERVVGENASLL 1083 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188 C P +GSP+P + W++ + +G + +++ G+L + D+G Y+C A N G+ Sbjct: 1084 C-PAQGSPKPRITWRRVPSSEALNGRPDVAVLNEGSLFLSSVSLADSGEYECQATNEVGS 1142 Query: 189 RESAIATLKIHIKPYLIT--GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 + L +++ P + ++ G +T +C G P+P+V+W + G +P Sbjct: 1143 ASRRV-KLVVYVPPSIREEGRTANMSGLAGQPLTLECDASGFPVPEVVWLKD--GQQIPE 1199 Query: 247 GRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304 DG SL + G YSC+AEN G L V+ PPS+ + + V Sbjct: 1200 ASAHRFLDGARSLHFPRIQENHSGLYSCQAENQAGRAQRDFNLAVFIPPSLLGAGAAQEV 1259 Query: 305 --ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362 +G + C +G P P + W +G + PG S H DG VL I + Sbjct: 1260 LGLAGADVKLECQTSGVPTPQVEWIKDGQP--LLPGDS----HILLQEDG-QVLRIISSH 1312 Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS-MAVFPCTA 421 D C A + AG +L++ S PP I + + + ++ A C A Sbjct: 1313 LGD-EGRYQCVAFSPAGQQAKDFQLSIHS----PPTIWGSNETGEVTVLEGHTAQLLCEA 1367 Query: 422 ICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474 P P I WY +G L + + G L L SD+G YTC AS+ G Sbjct: 1368 RGMPAPDITWYKDGTLLAPSSEVIYSKGGRQLQLGKAQHSDAGLYTCQASNSAG 1421 Score = 122 bits (295), Expect = 5e-26 Identities = 94/308 (30%), Positives = 138/308 (44%), Gaps = 18/308 (5%) Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVG 226 I A + + G YQCIA + AGT ++ + P L+ GP +V G + C+V Sbjct: 389 IPRASKAEEGVYQCIAVSRAGTGRASAQIVITDPPPQLVPGP-NVTVSPGETAILSCQVL 447 Query: 227 GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY 286 G+ ++ W R + GRV L D SL + +V+ +D G+Y C A N G AS + Sbjct: 448 GETPYNLTWVRDWRALPVKTGRVSQLRDLSLEVSSVVPSDGGQYQCVASNPNGLTRASTW 507 Query: 287 LTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHA 346 L V +PP ++++ S G R +C+A+G P+P + WS EG + P SR H Sbjct: 508 LLVREPPQVSINARSQRFSQGVEVRVSCSASGYPKPHVSWSREG---LALPEDSR--IHV 562 Query: 347 TAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN 406 D L I D+ N C A N G+ + TVT PP + Sbjct: 563 ----DAQGTLIIQGVAPEDAGN-YSCQAANEVGTD----EETVTLYYTDPPSVSAINAVV 613 Query: 407 QTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYT 466 T + AV C A P P + WY G +I + GTL + + + D+G YT Sbjct: 614 LT-AVGEEAVLLCAASGVPPPRVIWYRGGLEVIL--APEGSRSGTLRIPEAQERDAGLYT 670 Query: 467 CVASSRHG 474 C A + G Sbjct: 671 CKAVNELG 678 Score = 121 bits (292), Expect = 1e-25 Identities = 117/435 (26%), Positives = 171/435 (39%), Gaps = 31/435 (7%) Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS-AQGDTVVLECLPPRGSP 136 ++ GVY C A + GT R A+ + + +L P + + G+T +L C G Sbjct: 395 AEEGVYQCIAVSRAGTGR---ASAQIVITDPPPQLVPGPNVTVSPGETAILSC-QVLGET 450 Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196 N+ W ++ + L R+ + +L + +D G+YQC+A N G A L Sbjct: 451 PYNLTWVRDWRALPVK-TGRVSQLRDLSLEVSSVVPSDGGQYQCVASNPNGLTR-ASTWL 508 Query: 197 KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDG 255 + P + G V C G P P V W R G +P R+ V G Sbjct: 509 LVREPPQVSINARSQRFSQGVEVRVSCSASGYPKPHVSWSRE--GLALPEDSRIHVDAQG 566 Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315 +L + V D G YSC+A N VG + L DPPS++ V G A C Sbjct: 567 TLIIQGVAPEDAGNYSCQAANEVGTDEETVTLYYTDPPSVSAINAVVLTAVGEEAVLLCA 626 Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375 A+G P P + W G I+ P SR L I + + D+ C AV Sbjct: 627 ASGVPPPRVIWYRGGLEVILAPEGSRS-----------GTLRIPEAQERDA-GLYTCKAV 674 Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-YFE 434 N G + +L V P +T+ P + T+ + C A P P + W + Sbjct: 675 NELGDASAEIQLLVGY-----APRLTDPPQDVTVELGKSVFLTCRATGRPPPTVTWRRGD 729 Query: 435 GEALIQNHRRNV--TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492 G+AL R + G LV + + D Y C A + GK L+V P I Sbjct: 730 GQALEPGRRSRTGQRDSGVLVFERVSLEDQAPYVCEARNVFGKAQAEAQLVVTGHAPPQI 789 Query: 493 HFFRAADVSSLPGPP 507 A+ V L G P Sbjct: 790 -ASSASVVRVLEGQP 803 Score = 110 bits (264), Expect = 3e-22 Identities = 97/301 (32%), Positives = 132/301 (43%), Gaps = 21/301 (6%) Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85 QP TL C A G P P + W K G + + HR + A L F R HS G+Y C Sbjct: 1172 QPLTLECDASGFPVPEVVWLKDGQQIPEASAHRFLDGARSLHFPRIQEN--HS--GLYSC 1227 Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPESKQSA---QGDTVVLECLPPRGSPEPNVYW 142 +A N G A+ ++AV L + Q G V LEC G P P V W Sbjct: 1228 QAENQAGRAQR---DFNLAVFIPPSLLGAGAAQEVLGLAGADVKLEC-QTSGVPTPQVEW 1283 Query: 143 KKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201 K+GQ LL GDS + L + G ++ I + D GRYQC+A + AG +++ L IH Sbjct: 1284 IKDGQPLL-PGDSHILLQEDGQVLRIISSHLGDEGRYQCVAFSPAG-QQAKDFQLSIHSP 1341 Query: 202 PYLITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG-SLR 258 P + E +V G + C G P PD+ W + G P V G L+ Sbjct: 1342 PTIWGSNETGEVTVLEGHTAQLLCEARGMPAPDITWYKD-GTLLAPSSEVIYSKGGRQLQ 1400 Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PPSINLSPNSVNVESGNVARFTCTA 316 L +D G Y+C+A NS G S L VY P + + + +TC+A Sbjct: 1401 LGKAQHSDAGLYTCQASNSAGITKKSTNLEVYGERPEGCSSGQLIEKADLRDEGVYTCSA 1460 Query: 317 T 317 T Sbjct: 1461 T 1461 Score = 106 bits (255), Expect = 3e-21 Identities = 81/285 (28%), Positives = 118/285 (41%), Gaps = 20/285 (7%) Query: 166 VIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV 225 +I+ A D G Y C A N AG + + TLK+ + P + GP + +SVT +C Sbjct: 1444 LIEKADLRDEGVYTCSATNLAGESKKDV-TLKVLVPPNIEPGPVNKAVLENASVTLECLA 1502 Query: 226 GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASG 285 G P PD+ W + + + D L ++ L+D G Y C A N VG+ + Sbjct: 1503 SGVPPPDISWFKGRQPISTQRHLIVSTDGRVLHIERAQLSDAGSYRCVATNVVGSAALQY 1562 Query: 286 YLTVYDPPSINLSPNSVN-VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344 L V PP I L P+ V G R TC ATG P P + W +GN +S + Sbjct: 1563 GLRVNVPPRITLPPSLPGPVVLGTPFRLTCNATGTPSPMLLWLKDGN------PVSPEGT 1616 Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD----------- 393 VF G VLT+ +D+ C AV+ G L V S+ Sbjct: 1617 PGLKVFPGGQVLTVASARASDA-GGYSCVAVSAVGEDRRDIVLQVHSESLAWDGVCGVSI 1675 Query: 394 DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438 + PP I N ++ + C + P P++ W +G L Sbjct: 1676 AKVPPSILGEELNISVVVNESVALECRSHAVPPPVLRWQKDGRPL 1720 Score = 87.0 bits (206), Expect = 3e-15 Identities = 83/290 (28%), Positives = 124/290 (42%), Gaps = 34/290 (11%) Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138 D GVY C ATN G ++ ++ TL V V P +K + +V LECL G P P Sbjct: 1452 DEGVYTCSATNLAGESK-KDVTLKVLV-PPNIEPGPVNKAVLENASVTLECL-ASGVPPP 1508 Query: 139 NVYWKKNGQTLLFDGDSRMHLV---DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195 ++ W K Q + ++ HL+ DG L I+ A+ +DAG Y+C+A N G+ Sbjct: 1509 DISWFKGRQPI----STQRHLIVSTDGRVLHIERAQLSDAGSYRCVATNVVGSAALQYG- 1563 Query: 196 LKIHIKPYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR--VKVL 252 L++++ P + P G+ C G P P +LW + G P G +KV Sbjct: 1564 LRVNVPPRITLPPSLPGPVVLGTPFRLTCNATGTPSPMLLWLKD-GNPVSPEGTPGLKVF 1622 Query: 253 DDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD----------------PPSI 295 G L + + +D G YSC A ++VG L V+ PPSI Sbjct: 1623 PGGQVLTVASARASDAGGYSCVAVSAVGEDRRDIVLQVHSESLAWDGVCGVSIAKVPPSI 1682 Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPG--MSRDK 343 +++V C + P P + W +G PG +S DK Sbjct: 1683 LGEELNISVVVNESVALECRSHAVPPPVLRWQKDGRPLEPHPGIRLSADK 1732 Score = 87.0 bits (206), Expect = 3e-15 Identities = 112/431 (25%), Positives = 163/431 (37%), Gaps = 51/431 (11%) Query: 55 DTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL-E 113 D+ +L G L +L + G Y CE +N GT+ S+ L V V + L E Sbjct: 1798 DSQEQVLAVGRLLYLGQAQS---AQEGTYTCECSNVAGTS-SQEQQLEVLVPPQVTGLWE 1853 Query: 114 PESKQSA-QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ 172 P + S Q L+C G P P V W+++GQ + + + +L + A+ Sbjct: 1854 PLTTVSVIQDGNATLDC-NATGKPLPVVTWERDGQPVRMELGIWLQN-QNHSLHVDRAQA 1911 Query: 173 TDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED----VVAQTGSSVTFQCRVGGD 228 + AG Y C+A N AG E A L + P+L TG D V A S+T C G Sbjct: 1912 SHAGGYSCVAENIAGRAERRFA-LSVLAPPHL-TGDSDSLTNVTATLHGSLTLLCEAEGI 1969 Query: 229 PLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288 P P V W R G + G L + AD G E A G +T Sbjct: 1970 PPPTVQWFRE--GQPISPGEGTYLLAVPPMFQKMGDADAGFELLPHEEE-----AQGRVT 2022 Query: 289 VYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348 Y V N A C P P + W EG G+S Sbjct: 2023 EYR-----------EVVENNPAYLYCDTNAIPPPELTWYREGQPLSAVDGVS-------- 2063 Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ- 407 V G +L + D+ C A N G ++ +L V + PP+I Sbjct: 2064 VLQGGRILQLPLVQAEDA-GRYSCKASNEVGEDWLHYELLVLT-----PPVIPGDTQELV 2117 Query: 408 ---TLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSG 463 T+ S C A+ P P ++W+ G + + R V +G L + + +D+ Sbjct: 2118 EEVTVNASSAVSLECPALGNPAPALSWFQNGLPVSPSPRLQVLEEGQVLKVSTAEVTDAA 2177 Query: 464 TYTCVASSRHG 474 Y CVA ++ G Sbjct: 2178 NYMCVAENQAG 2188 Score = 80.2 bits (189), Expect = 3e-13 Identities = 66/194 (34%), Positives = 88/194 (45%), Gaps = 12/194 (6%) Query: 146 GQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL 204 GQ L DGDS+ ++ G L+ + A+ G Y C N AGT S L++ + P Sbjct: 1790 GQPLPGDGDSQEQVLAVGRLLYLGQAQSAQEGTYTCECSNVAGT-SSQEQQLEVLVPPQ- 1847 Query: 205 ITG---PEDVVA--QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL 259 +TG P V+ Q G++ T C G PLP V W R M LG + SL + Sbjct: 1848 VTGLWEPLTTVSVIQDGNA-TLDCNATGKPLPVVTWERDGQPVRMELGIWLQNQNHSLHV 1906 Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV-NVESGNVARFT--CTA 316 D + G YSC AEN G L+V PP + +S+ NV + T C A Sbjct: 1907 DRAQASHAGGYSCVAENIAGRAERRFALSVLAPPHLTGDSDSLTNVTATLHGSLTLLCEA 1966 Query: 317 TGRPEPTMFWSVEG 330 G P PT+ W EG Sbjct: 1967 EGIPPPTVQWFREG 1980 Score = 80.2 bits (189), Expect = 3e-13 Identities = 61/213 (28%), Positives = 100/213 (46%), Gaps = 17/213 (7%) Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179 +G V L C G P P++ W K G L G +DG LV++ R D+G Y Sbjct: 2397 EGQEVRLGC-EAEGQPPPDIAWLKEGGPLDQHVGPHLRFYLDGSTLVLKGLRAADSGAYT 2455 Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPED---VVAQTGSSVTFQCRVGGDPLPDVLWR 236 C+A N AG ++ + T+ + + P + D +V++TG VT C V G P V W Sbjct: 2456 CVAHNPAG-EDARLHTVNVLVPPTIKQQASDTGTLVSRTGELVTMMCPVQGSPPIHVSWL 2514 Query: 237 RSAGGGNMPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV----- 289 + G + L + +L + +LR+ V LAD G ++C A + G + + L V Sbjct: 2515 KD--GLPLALSQRTLLHNSGRTLRISQVQLADSGVFTCVASSPAGVANRNFTLLVDKGSV 2572 Query: 290 -YDPPSINLSPNSVNVESGNVARFTCTATGRPE 321 D PS+ + P ++++ + + A+ PE Sbjct: 2573 LEDSPSVRV-PKALSMRATDCAKIQVPPILEPE 2604 Score = 78.2 bits (184), Expect = 1e-12 Identities = 88/320 (27%), Positives = 124/320 (38%), Gaps = 44/320 (13%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I P++ V + TL C A G P P I W+KG + + H + G + + Sbjct: 1479 PNIEPGPVNKAVLENASVTLECLASGVPPPDISWFKGRQPISTQRHLIVSTDGRVLHIER 1538 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131 SDAG Y C ATN G+A + L V V L P T Sbjct: 1539 AQ---LSDAGSYRCVATNVVGSAALQYG-LRVNV-PPRITLPPSLPGPVVLGTPFRLTCN 1593 Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRE 190 G+P P + W K+G + +G + + GG L + AR +DAG Y C+A +A G Sbjct: 1594 ATGTPSPMLLWLKDGNPVSPEGTPGLKVFPGGQVLTVASARASDAGGYSCVAVSAVGEDR 1653 Query: 191 SAIATLKIHIK---------------PYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVL 234 I L++H + P I G E ++ SV +CR P P + Sbjct: 1654 RDI-VLQVHSESLAWDGVCGVSIAKVPPSILGEELNISVVVNESVALECRSHAVPPPVLR 1712 Query: 235 W-------------RRSAGGGNMPLGRV------KVLDDG--SLRLDNVILADEGEYSCE 273 W R SA + + R K + G L +D V + D G Y+CE Sbjct: 1713 WQKDGRPLEPHPGIRLSADKALLEVCRCAARCPEKPNEQGRVDLWVDRVAVWDAGHYTCE 1772 Query: 274 AENSVGAVSASGYLTVYDPP 293 A N G L V+ P Sbjct: 1773 AINQAGRSEKHFNLHVWGQP 1792 Score = 77.0 bits (181), Expect = 3e-12 Identities = 77/313 (24%), Positives = 130/313 (41%), Gaps = 25/313 (7%) Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGS-LRLDNVILADEGEYSCE 273 G V C G P PD+ W + G + +G ++ DGS L L + AD G Y+C Sbjct: 2398 GQEVRLGCEAEGQPPPDIAWLKEGGPLDQHVGPHLRFYLDGSTLVLKGLRAADSGAYTCV 2457 Query: 274 AENSVGAVSASGYLTVYDPPSINLSPNSVNV---ESGNVARFTCTATGRPEPTMFWSVEG 330 A N G + + V PP+I + +G + C G P + W +G Sbjct: 2458 AHNPAGEDARLHTVNVLVPPTIKQQASDTGTLVSRTGELVTMMCPVQGSPPIHVSWLKDG 2517 Query: 331 ------NRTIIFPG-----MSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379 RT++ +S+ + + VF V ++N + S + + Sbjct: 2518 LPLALSQRTLLHNSGRTLRISQVQLADSGVFTCVASSPAGVANRNFTLLVDKGSVLEDSP 2577 Query: 380 SSFVRGKLTVTSDDD---RPPPIITNGP-SNQTLPIK-SMAVFPCTAICTPEPIIAWYFE 434 S V L++ + D + PPI+ N + + S V PC A +P P+++W + Sbjct: 2578 SVRVPKALSMRATDCAKIQVPPILEPEEFQNDVMAAQGSEVVLPCEARGSPLPLVSWMKD 2637 Query: 435 GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV-DSPINPNIH 493 GE L+ +++ L L+ + DSGTY+C+A+S G+ L V + + P H Sbjct: 2638 GEPLLP---QSLEQGPGLKLEAVSIGDSGTYSCMAASEAGEARRHFQLTVMELSLTPGAH 2694 Query: 494 FFRAADVSSLPGP 506 + +P P Sbjct: 2695 LELLCEARGIPPP 2707 Score = 69.3 bits (162), Expect = 6e-10 Identities = 52/179 (29%), Positives = 79/179 (44%), Gaps = 10/179 (5%) Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82 V + PA L C P P + WY+ G + + S+L G + L DAG Sbjct: 2027 VVENNPAYLYCDTNAIPPPELTWYREGQPLSAVDGVSVLQGGRILQLPLVQAE---DAGR 2083 Query: 83 YWCEATNSYGT--ARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140 Y C+A+N G L V+ + + E V LEC P G+P P + Sbjct: 2084 YSCKASNEVGEDWLHYELLVLTPPVIPGDTQELVEEVTVNASSAVSLEC-PALGNPAPAL 2142 Query: 141 YWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKI 198 W +NG L R+ +++ G ++ + A TDA Y C+A N AG+ E + TL++ Sbjct: 2143 SWFQNG--LPVSPSPRLQVLEEGQVLKVSTAEVTDAANYMCVAENQAGSAEK-LFTLRV 2198 Score = 68.9 bits (161), Expect = 8e-10 Identities = 90/337 (26%), Positives = 129/337 (38%), Gaps = 45/337 (13%) Query: 23 VARHQPATLNCRAGGSPSPAIRWYK-GGVLVVS-DTHRSILPAGGLFFLRATHGRVHSDA 80 V Q L C A G P P I W K GG L H G L+ G +D+ Sbjct: 2395 VLEGQEVRLGCEAEGQPPPDIAWLKEGGPLDQHVGPHLRFYLDGSTLVLK---GLRAADS 2451 Query: 81 GVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139 G Y C A N G AR + V ++ + + S G+ V + C P +GSP + Sbjct: 2452 GAYTCVAHNPAGEDARLHTVNVLVPPTIKQQASDTGTLVSRTGELVTMMC-PVQGSPPIH 2510 Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199 V W K+G L + +H G L I + D+G + C+A + AG TL + Sbjct: 2511 VSWLKDGLPLALSQRTLLH-NSGRTLRISQVQLADSGVFTCVASSPAGVANRNF-TLLVD 2568 Query: 200 IKPYLITGPEDVVAQTGSSVTFQC-RVGGDPL--PDVLWR--RSAGGGNM---------P 245 L P V + S C ++ P+ P+ +A G + P Sbjct: 2569 KGSVLEDSPSVRVPKALSMRATDCAKIQVPPILEPEEFQNDVMAAQGSEVVLPCEARGSP 2628 Query: 246 LGRVKVLDDG------------SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293 L V + DG L+L+ V + D G YSC A + G LTV + Sbjct: 2629 LPLVSWMKDGEPLLPQSLEQGPGLKLEAVSIGDSGTYSCMAASEAGEARRHFQLTVME-- 2686 Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330 ++L+P G C A G P P + W +G Sbjct: 2687 -LSLTP-------GAHLELLCEARGIPPPNIIWHKDG 2715 Score = 66.1 bits (154), Expect = 6e-09 Identities = 59/222 (26%), Positives = 98/222 (44%), Gaps = 16/222 (7%) Query: 115 ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLV-IQDARQ 172 E ++ + + L C P P + W + GQ L DG S ++ GG ++ + + Sbjct: 2023 EYREVVENNPAYLYC-DTNAIPPPELTWYREGQPLSAVDGVS---VLQGGRILQLPLVQA 2078 Query: 173 TDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP-----EDVVAQTGSSVTFQCRVGG 227 DAGRY C A N G E + + + P +I G E+V S+V+ +C G Sbjct: 2079 EDAGRYSCKASNEVG--EDWLHYELLVLTPPVIPGDTQELVEEVTVNASSAVSLECPALG 2136 Query: 228 DPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGY 286 +P P + W ++ G P R++VL++G L++ + D Y C AEN G+ Sbjct: 2137 NPAPALSWFQN-GLPVSPSPRLQVLEEGQVLKVSTAEVTDAANYMCVAENQAGSAEKLFT 2195 Query: 287 LTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328 L V ++ L+ + +SG GR + + SV Sbjct: 2196 LRVQGTHTLRLA-RAQPADSGTYLCEALNPAGRDQKMVQLSV 2236 Score = 63.3 bits (147), Expect = 4e-08 Identities = 63/222 (28%), Positives = 93/222 (41%), Gaps = 20/222 (9%) Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP-NSVNVESGNVARFTCTAT 317 ++ L DEG Y+C A N G L V PP+I P N +E+ +V C A+ Sbjct: 1445 IEKADLRDEGVYTCSATNLAGESKKDVTLKVLVPPNIEPGPVNKAVLENASVT-LECLAS 1503 Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377 G P P + W +G + I + H DG VL I +D+ + C A N Sbjct: 1504 GVPPPDISW-FKGRQPI------STQRHLIVSTDG-RVLHIERAQLSDA-GSYRCVATNV 1554 Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPS-NQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436 GS+ ++ L V PP IT PS + + + C A TP P++ W +G Sbjct: 1555 VGSAALQYGLRV-----NVPPRITLPPSLPGPVVLGTPFRLTCNATGTPSPMLLWLKDGN 1609 Query: 437 ALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 + + L + SD+G Y+CVA S G+ Sbjct: 1610 PVSPEGTPGLKVFPGGQVLTVASARASDAGGYSCVAVSAVGE 1651 Score = 61.7 bits (143), Expect = 1e-07 Identities = 97/372 (26%), Positives = 139/372 (37%), Gaps = 41/372 (11%) Query: 17 QPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75 +PL V+V + ATL+C A G P P + W + G V + I L + Sbjct: 1853 EPLTTVSVIQDGNATLDCNATGKPLPVVTWERDGQPVRMEL--GIWLQNQNHSLHVDRAQ 1910 Query: 76 VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDTVVLECLPPRG 134 S AG Y C A N G A R A +A + + +A ++ L C G Sbjct: 1911 A-SHAGGYSCVAENIAGRAERRFALSVLAPPHLTGDSDSLTNVTATLHGSLTLLC-EAEG 1968 Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194 P P V W + GQ + + + V + Q DAG ++ + E A Sbjct: 1969 IPPPTVQWFREGQPISPGEGTYLLAVPP---MFQKMGDADAG-FELLPHE-----EEAQG 2019 Query: 195 TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254 +T +VV + + C P P++ W R G + V VL Sbjct: 2020 R---------VTEYREVVENNPAYL--YCDTNAIPPPELTWYRE-GQPLSAVDGVSVLQG 2067 Query: 255 GS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI----NLSPNSVNVESGNV 309 G L+L V D G YSC+A N VG L V PP I V V + + Sbjct: 2068 GRILQLPLVQAEDAGRYSCKASNEVGEDWLHYELLVLTPPVIPGDTQELVEEVTVNASSA 2127 Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369 C A G P P + W G P + V + VL ++ + D+ N Sbjct: 2128 VSLECPALGNPAPALSWFQNGLPVSPSPRLQ--------VLEEGQVLKVSTAEVTDAAN- 2178 Query: 370 IVCSAVNYAGSS 381 +C A N AGS+ Sbjct: 2179 YMCVAENQAGSA 2190 Score = 57.2 bits (132), Expect = 3e-06 Identities = 67/230 (29%), Positives = 88/230 (38%), Gaps = 25/230 (10%) Query: 292 PPSINLS--PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349 PP I S NV G R C A G+P P + W EG G H Sbjct: 2381 PPQIQNSGMTQEHNVLEGQEVRLGCEAEGQPPPDIAWLKEGGPLDQHVGP-----HLRFY 2435 Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409 DG T L + DS C A N AG + V PP I TL Sbjct: 2436 LDGST-LVLKGLRAADS-GAYTCVAHNPAGEDARLHTVNVLV----PPTIKQQASDTGTL 2489 Query: 410 PIKS--MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYT 466 ++ + C +P ++W +G L + R + N G TL + + +DSG +T Sbjct: 2490 VSRTGELVTMMCPVQGSPPIHVSWLKDGLPLALSQRTLLHNSGRTLRISQVQLADSGVFT 2549 Query: 467 CVASSRHG-------KYVWSGALLVDSPI--NPNIHFFRAADVSSLPGPP 507 CVASS G V G++L DSP P RA D + + PP Sbjct: 2550 CVASSPAGVANRNFTLLVDKGSVLEDSPSVRVPKALSMRATDCAKIQVPP 2599 Score = 54.4 bits (125), Expect = 2e-05 Identities = 32/84 (38%), Positives = 42/84 (50%), Gaps = 4/84 (4%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 +VTV A L C A G P+P I WYK G L+ + G L HSD Sbjct: 1352 EVTVLEGHTAQLLCEARGMPAPDITWYKDGTLLAPSSEVIYSKGGRQLQLGKAQ---HSD 1408 Query: 80 AGVYWCEATNSYG-TARSRNATLH 102 AG+Y C+A+NS G T +S N ++ Sbjct: 1409 AGLYTCQASNSAGITKKSTNLEVY 1432 Score = 52.4 bits (120), Expect = 7e-05 Identities = 57/185 (30%), Positives = 80/185 (43%), Gaps = 15/185 (8%) Query: 362 DKNDSRNTIV--CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419 +K D R+ V CSA N AG S L V PP I GP N+ + + C Sbjct: 1446 EKADLRDEGVYTCSATNLAGESKKDVTLKVLV-----PPNIEPGPVNKAVLENASVTLEC 1500 Query: 420 TAICTPEPIIAWYFEGEALIQNHRRN-VTNDGTLV-LKDLDKSDSGTYTCVASSRHGKYV 477 A P P I+W F+G I R V+ DG ++ ++ SD+G+Y CVA++ G Sbjct: 1501 LASGVPPPDISW-FKGRQPISTQRHLIVSTDGRVLHIERAQLSDAGSYRCVATNVVGSAA 1559 Query: 478 WSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDT-SVTLSW-SQNNKIGSSSI 535 L V+ P P I + + G P + +T N T T S L W N + Sbjct: 1560 LQYGLRVNVP--PRITLPPSLPGPVVLGTPFR-LTCNATGTPSPMLLWLKDGNPVSPEGT 1616 Query: 536 LGYQV 540 G +V Sbjct: 1617 PGLKV 1621 Score = 50.8 bits (116), Expect = 2e-04 Identities = 41/128 (32%), Positives = 55/128 (42%), Gaps = 11/128 (8%) Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA----QGDTVVLECLPPR 133 +D+G Y CEA N G R + ++ F+ P Q A GD L C Sbjct: 2212 ADSGTYLCEALNPAG--RDQKMVQLSVLVPPSFKQAPGGPQEAVQVRAGDKATLNC-ETD 2268 Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193 PEP V W K+ Q L G L G L I D++ +D G Y C N AG A Sbjct: 2269 SLPEPAVTWFKDQQPLAL-GQRIQGLQGGQKLEILDSQVSDKGVYSCKVSNTAG---EAT 2324 Query: 194 ATLKIHIK 201 T +++I+ Sbjct: 2325 RTFELNIQ 2332 Score = 49.2 bits (112), Expect = 7e-04 Identities = 36/126 (28%), Positives = 57/126 (45%), Gaps = 9/126 (7%) Query: 170 ARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP----EDVVAQTGSSVTFQCRV 225 A+ D+G Y C A N AG R+ + L + + P P E V + G T C Sbjct: 2209 AQPADSGTYLCEALNPAG-RDQKMVQLSVLVPPSFKQAPGGPQEAVQVRAGDKATLNCET 2267 Query: 226 GGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSA 283 P P V W + + LG R++ L G L + + ++D+G YSC+ N+ G + Sbjct: 2268 DSLPEPAVTWFKDQQP--LALGQRIQGLQGGQKLEILDSQVSDKGVYSCKVSNTAGEATR 2325 Query: 284 SGYLTV 289 + L + Sbjct: 2326 TFELNI 2331 Score = 48.8 bits (111), Expect = 9e-04 Identities = 40/135 (29%), Positives = 61/135 (45%), Gaps = 10/135 (7%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 V G+ ++E+ VTV +L C A G+P+PA+ W++ G+ V +L G Sbjct: 2108 VIPGDTQELVEE---VTVNASSAVSLECPALGNPAPALSWFQNGLPVSPSPRLQVLEEGQ 2164 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 + L+ + V +DA Y C A N G+A + TL V + L Q A T Sbjct: 2165 V--LKVSTAEV-TDAANYMCVAENQAGSA-EKLFTLRV---QGTHTLRLARAQPADSGTY 2217 Query: 126 VLECLPPRGSPEPNV 140 + E L P G + V Sbjct: 2218 LCEALNPAGRDQKMV 2232 Score = 48.8 bits (111), Expect = 9e-04 Identities = 42/130 (32%), Positives = 55/130 (42%), Gaps = 20/130 (15%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 DV A+ L C A GSP P + W K G ++ +S+ GL + G D Sbjct: 2609 DVMAAQGSEVVLPCEARGSPLPLVSWMKDGEPLLP---QSLEQGPGLKLEAVSIG----D 2661 Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139 +G Y C A + G AR H + E L P G + L C RG P PN Sbjct: 2662 SGTYSCMAASEAGEARR-----HFQLTVMELSLTP-------GAHLELLC-EARGIPPPN 2708 Query: 140 VYWKKNGQTL 149 + W K+GQ L Sbjct: 2709 IIWHKDGQAL 2718 Score = 47.6 bits (108), Expect = 0.002 Identities = 30/90 (33%), Positives = 39/90 (43%), Gaps = 4/90 (4%) Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP- 299 G L ++V +LRL AD G Y CEA N G L+V PPS +P Sbjct: 2188 GSAEKLFTLRVQGTHTLRLARAQPADSGTYLCEALNPAGRDQKMVQLSVLVPPSFKQAPG 2247 Query: 300 ---NSVNVESGNVARFTCTATGRPEPTMFW 326 +V V +G+ A C PEP + W Sbjct: 2248 GPQEAVQVRAGDKATLNCETDSLPEPAVTW 2277 Score = 37.9 bits (84), Expect = 1.7 Identities = 32/129 (24%), Positives = 52/129 (40%), Gaps = 11/129 (8%) Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN--QTL 409 G L + DS T +C A+N AG +L+V PP P + + Sbjct: 2200 GTHTLRLARAQPADS-GTYLCEALNPAGRDQKMVQLSVLV-----PPSFKQAPGGPQEAV 2253 Query: 410 PIKS--MAVFPCTAICTPEPIIAWYFEGEALIQNHR-RNVTNDGTLVLKDLDKSDSGTYT 466 +++ A C PEP + W+ + + L R + + L + D SD G Y+ Sbjct: 2254 QVRAGDKATLNCETDSLPEPAVTWFKDQQPLALGQRIQGLQGGQKLEILDSQVSDKGVYS 2313 Query: 467 CVASSRHGK 475 C S+ G+ Sbjct: 2314 CKVSNTAGE 2322 Score = 37.5 bits (83), Expect = 2.2 Identities = 25/74 (33%), Positives = 32/74 (43%), Gaps = 3/74 (4%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80 V V ATLNC P PA+ W+K + L G L +V SD Sbjct: 2253 VQVRAGDKATLNCETDSLPEPAVTWFKDQQPLALGQRIQGLQGGQK--LEILDSQV-SDK 2309 Query: 81 GVYWCEATNSYGTA 94 GVY C+ +N+ G A Sbjct: 2310 GVYSCKVSNTAGEA 2323 >UniRef50_Q4S8U5 Cluster: Chromosome 7 SCAF14703, whole genome shotgun sequence; n=5; Tetraodontidae|Rep: Chromosome 7 SCAF14703, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 2095 Score = 170 bits (414), Expect = 2e-40 Identities = 205/832 (24%), Positives = 342/832 (41%), Gaps = 67/832 (8%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 D+T + + CR G P +I+W K G + + D HR ++ G LR T + +D Sbjct: 516 DMTAVAGRNTYITCRVIGYPYYSIKWLKDG-MQLPDNHRQVVFENGT--LRLTDVQKGAD 572 Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139 G Y C S N T+HV V + ++ G + + C+ G Sbjct: 573 EGTYLCSVLIQPQV--SINQTVHVTVKVPPLIQPFDIPSTSVGKLIYIACVVSSGDMPIR 630 Query: 140 VYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196 + W K+GQ ++ S + + +L I G Y CIA N A T S L Sbjct: 631 ITWHKDGQPIVPGSASGVAIETKDFMSSLQITKVTLKHNGNYTCIASNTAAT-VSWERQL 689 Query: 197 KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN------MPL-GRV 249 + + P + P + G + C V G P P V+W+ + G GN +PL GR+ Sbjct: 690 IVTVPPRFVVQPNNQDCIYGKAGVLNCSVEGYPPPKVMWKHAKGVGNPQQYHPVPLTGRI 749 Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSAS-GYLTVYDPPSINLSPNSVNVESG 307 +++ +GSL + +V+ D G Y C+A N VG+ +S ++TV P I PN+ G Sbjct: 750 QIMSNGSLLIRHVLEEDRGYYLCQASNGVGSDISREHDHVTVKIPAMITSHPNTTMARKG 809 Query: 308 NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG---VTVLTINDTDKN 364 CTA G + W E T+I +Y T G ++ L +N ++ Sbjct: 810 QTKELNCTARGEQPIIIRW--ERGDTVI-DAERNPRYSITINKKGDEVISTLKLNPAERG 866 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424 DS C A+N G +LTV D PP + ++++ ++ + F +I T Sbjct: 867 DSV-FFSCHAINSYGEGRGLIQLTVQEPPD-PPELEVREVKDRSMNLRWIQRFDGNSIIT 924 Query: 425 PEPIIAWYFEGEALIQNHR---RNV--TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479 I ++ ++ +H RN+ TN+ ++ +L + CV S R Y Sbjct: 925 SYDI---EYKNKSDSWDHMYTTRNISPTNNQANIV-ELHPA------CVYSIRMYSYNKI 974 Query: 480 GALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK-IGSSSILGY 538 G L P+ + + + GPP I +T S+ ++W K + + I GY Sbjct: 975 GRSL------PSKELTISTEEAPPDGPPMDVILQPMTSQSIRVTWRAPKKELQNGVIRGY 1028 Query: 539 QVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598 Q+ RE G+N V + Y + +L Y +V+ N G +GP Sbjct: 1029 QIGY--RENGPGSN---GQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAG-TGP 1082 Query: 599 SPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEI--- 655 S + T +D ++ + + + + + A + S + W Sbjct: 1083 SSTEINATTLEDEDARKQRPSAITDSYPPLFPVPSEPPQNVRAISVTSDEAVITWSEPPR 1142 Query: 656 LNFY-YLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKF 714 L + L+G + F L + EM+ I + + E+ L K+T Y ++ + + Sbjct: 1143 LTLHGVLKGYRVVFWSLFSNGEWGEMQNITTTREQ--VELRGLEKFTNYSVQVLAYTQAG 1200 Query: 715 EGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWL 774 +G SN QT +D+P GPP I+ + ++V + W PP NGII Y + + Sbjct: 1201 DGVRSNVLYIQTREDLP-GPPAGIKAVPSSPSSVVVSWLPP--NKPNGIIRKYTI---YC 1254 Query: 775 DVPANKSMVAINTTVH-QATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825 P + + + +T+L+ G Y + AA T G G FS KV Sbjct: 1255 SSPGSGQPAPSEYEANPEMLFYRITHLSRGKQYHIWAAAVTTAGKGNFSSKV 1306 Score = 123 bits (296), Expect = 3e-26 Identities = 138/538 (25%), Positives = 218/538 (40%), Gaps = 63/538 (11%) Query: 13 YIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAGGLFFL- 69 Y + L VT + +L C AGG+PS +RWY G + H + A G L Sbjct: 9 YFVNASLQRVTYSSSVGVSLPCPAGGTPSAILRWYLATGDDIYDVPHIRHVHANGTLQLY 68 Query: 70 ----RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 A + +H + Y+C A N G RS N + AV RE + + ++S +G+ Sbjct: 69 PFSPSAYNSYIHDND--YFCTAENQAGKIRSPNIRIK-AVFREPYTVRVADQRSMRGNVA 125 Query: 126 VLECLPPRGSPE--PNVYWKKNGQTLLFDGD------SRMH------------LVDGGNL 165 V +CL P E V W+++ +++ + D +R+H L G L Sbjct: 126 VFKCLIPAAVQEYVSVVSWERDTVSIVPEDDRSVWDWTRLHPGSTGIPGNRFSLTSFGAL 185 Query: 166 VIQDARQTDA-GRYQCIARN--AAGTRESAIATLKI----HIKPYLITGPEDVVAQTGSS 218 I + ++ DA Y+CI R+ + TR+S A L + P ++ + G S Sbjct: 186 YISEVQKEDALSTYRCITRHKYSGETRQSNGARLSVMDPNESSPTILDSFQAGEVYAGQS 245 Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSV 278 + C GG P P V W + G +P L + ++ L D G Y+CE NS Sbjct: 246 IELPCIAGGYPNPTVRWLKD--GRPLPSDARWTRRLTGLTISDLRLEDSGSYACEVTNSF 303 Query: 279 GAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPG 338 G+ SG L V DP + LSP ++ + FTC+ G PE T+ W N +I P Sbjct: 304 GSKEVSGQLHVIDPLRVTLSPKNLKTGISSTLFFTCSVEGSPEYTITWF--RNTELIVPD 361 Query: 339 MSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398 H + L I K S C A + ++ +D P Sbjct: 362 Q-----HISIQGQNNDTLQITAAQKFHS-GAYQCFA---SRKGHTAQDFSIILLEDGTPR 412 Query: 399 IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT----NDGTLV- 453 I+++ P + ++ C A P P I W + E ++++ + +DG V Sbjct: 413 IVSSFSERVVNPGEPFSLM-CAAKGAPPPSITWTLDDEPVVRDSTYKTSQYTLSDGLTVS 471 Query: 454 ---LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPT 508 + D G Y CVA + G + + V P P I R D++++ G T Sbjct: 472 HVNVSSPHIRDGGVYRCVARNSAGSAEYQARINVRGP--PRIRPMR--DMTAVAGRNT 525 Score = 122 bits (293), Expect = 8e-26 Identities = 121/490 (24%), Positives = 192/490 (39%), Gaps = 36/490 (7%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 +P I++ V Q L C AGG P+P +RW K G + SD + G L Sbjct: 228 SPTILDSFQAGEVYAGQSIELPCIAGGYPNPTVRWLKDGRPLPSDARWTRRLTG----LT 283 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130 + R+ D+G Y CE TNS+G+ + + LHV + L P++ ++ T+ C Sbjct: 284 ISDLRLE-DSGSYACEVTNSFGS-KEVSGQLHV-IDPLRVTLSPKNLKTGISSTLFFTC- 339 Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190 GSPE + W +N + ++ D + + L I A++ +G YQC A T + Sbjct: 340 SVEGSPEYTITWFRNTELIVPDQHISIQGQNNDTLQITAAQKFHSGAYQCFASRKGHTAQ 399 Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR---RSAGGGNMPLG 247 L P +++ + V G + C G P P + W + Sbjct: 400 DFSIILLEDGTPRIVSSFSERVVNPGEPFSLMCAAKGAPPPSITWTLDDEPVVRDSTYKT 459 Query: 248 RVKVLDDG----SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303 L DG + + + + D G Y C A NS G+ + V PP I + Sbjct: 460 SQYTLSDGLTVSHVNVSSPHIRDGGVYRCVARNSAGSAEYQARINVRGPPRIR-PMRDMT 518 Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363 +G TC G P ++ W + GM H VF+ T L + D K Sbjct: 519 AVAGRNTYITCRVIGYPYYSIKW--------LKDGMQLPDNHRQVVFENGT-LRLTDVQK 569 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423 T +CS + S + + VT + PP+I T + + C Sbjct: 570 GADEGTYLCSVLIQPQVS-INQTVHVTV---KVPPLIQPFDIPST-SVGKLIYIACVVSS 624 Query: 424 TPEPI-IAWYFEGEALIQNHRRNV---TND--GTLVLKDLDKSDSGTYTCVASSRHGKYV 477 PI I W+ +G+ ++ V T D +L + + +G YTC+AS+ Sbjct: 625 GDMPIRITWHKDGQPIVPGSASGVAIETKDFMSSLQITKVTLKHNGNYTCIASNTAATVS 684 Query: 478 WSGALLVDSP 487 W L+V P Sbjct: 685 WERQLIVTVP 694 Score = 110 bits (264), Expect = 3e-22 Identities = 210/871 (24%), Positives = 345/871 (39%), Gaps = 128/871 (14%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I+ + V +P +L C A G+P P+I W VV D+ L Sbjct: 411 PRIVSSFSERVVNPGEPFSLMCAAKGAPPPSITWTLDDEPVVRDSTYKTSQYTLSDGLTV 470 Query: 72 THGRVHS----DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVV 126 +H V S D GVY C A NS G+A + A ++V R R+ P +A G Sbjct: 471 SHVNVSSPHIRDGGVYRCVARNSAGSAEYQ-ARINV---RGPPRIRPMRDMTAVAGRNTY 526 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ-TDAGRYQC--IAR 183 + C G P ++ W K+G L + R + + G L + D ++ D G Y C + + Sbjct: 527 ITCRVI-GYPYYSIKWLKDGMQL--PDNHRQVVFENGTLRLTDVQKGADEGTYLCSVLIQ 583 Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLP-DVLWRRSAGG 241 ++ T+K+ P LI P D+ + + G + C V +P + W + Sbjct: 584 PQVSINQTVHVTVKV---PPLIQ-PFDIPSTSVGKLIYIACVVSSGDMPIRITWHKDGQP 639 Query: 242 ---GNMPLGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297 G+ ++ D SL++ V L G Y+C A N+ VS L V PP + Sbjct: 640 IVPGSASGVAIETKDFMSSLQITKVTLKHNGNYTCIASNTAATVSWERQLIVTVPPRFVV 699 Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 PN+ + G C+ G P P + W + + + P +YH + + +++ Sbjct: 700 QPNNQDCIYGKAGVLNCSVEGYPPPKVMW--KHAKGVGNP----QQYHPVPLTGRIQIMS 753 Query: 358 INDT----DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413 + R +C A N GS R VT + P +IT+ P N T+ K Sbjct: 754 NGSLLIRHVLEEDRGYYLCQASNGVGSDISREHDHVTV---KIPAMITSHP-NTTMARKG 809 Query: 414 MA-VFPCTAICTPEPIIAWYFEGEALI---QNHRRNVTND-------GTLVLKDLDKSDS 462 CTA +PII + G+ +I +N R ++T + TL L ++ DS Sbjct: 810 QTKELNCTA-RGEQPIIIRWERGDTVIDAERNPRYSITINKKGDEVISTLKLNPAERGDS 868 Query: 463 GTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTL 522 ++C A + +G+ L V P P PP + V D S+ L Sbjct: 869 VFFSCHAINSYGEGRGLIQLTVQEP----------------PDPPELEV-REVKDRSMNL 911 Query: 523 SWSQNNKIGSSSILGYQVEVFSR-ETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGI 581 W Q G+S I Y +E ++ ++ T RN I+ +Q + V L P Sbjct: 912 RWIQRFD-GNSIITSYDIEYKNKSDSWDHMYTTRN------ISPTNNQANIV--ELHPAC 962 Query: 582 TYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEA 641 Y + + N G S P S +T+ + + +G + D I++ Sbjct: 963 VYSIRMYSYNKIGRSLP---SKELTISTE-EAPPDGPPM------------DVILQ---- 1002 Query: 642 TPIDSKTIKLMWEI----LNFYYLEGLFIYFRPL-DNITIEYEMKTILHSNDVSGFEITS 696 P+ S++I++ W L + G I +R +Y + + + D + + + Sbjct: 1003 -PMTSQSIRVTWRAPKKELQNGVIRGYQIGYRENGPGSNGQYSIVEMKATGDSEVYTLDN 1061 Query: 697 LRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDD--------------------VPDGPPI 736 L+K+ +Y + F + G S A TL+D VP PP Sbjct: 1062 LKKFAQYGVVVQAFNRAGTGPSSTEINATTLEDEDARKQRPSAITDSYPPLFPVPSEPPQ 1121 Query: 737 NIEMFILNTTTVHLKWS-PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSL 795 N+ + + + WS PP L L +G++ GY VV W + +N + + Sbjct: 1122 NVRAISVTSDEAVITWSEPPRLTL-HGVLKGYRVVF-W-SLFSNGEWGEMQNITTTREQV 1178 Query: 796 IMTNLTSGVSYSVQIAAETIIGLGPFSQKVY 826 + L +YSVQ+ A T G G S +Y Sbjct: 1179 ELRGLEKFTNYSVQVLAYTQAGDGVRSNVLY 1209 Score = 108 bits (259), Expect = 1e-21 Identities = 141/571 (24%), Positives = 230/571 (40%), Gaps = 38/571 (6%) Query: 83 YWCEATNSYG--TARSRNATLHVAVLREEFRLEPESKQSAQ---GDTVVLECLPPRGSPE 137 Y C + Y T +S A L V E +S Q+ + G ++ L C+ G P Sbjct: 199 YRCITRHKYSGETRQSNGARLSVMDPNESSPTILDSFQAGEVYAGQSIELPCIAG-GYPN 257 Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197 P V W K+G+ L D L L I D R D+G Y C N+ G++E + L Sbjct: 258 PTVRWLKDGRPLPSDARWTRRLT---GLTISDLRLEDSGSYACEVTNSFGSKEVS-GQLH 313 Query: 198 IHIKPYLIT-GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDD 254 + I P +T P+++ S++ F C V G P + W R+ +P + + ++ Sbjct: 314 V-IDPLRVTLSPKNLKTGISSTLFFTCSVEGSPEYTITWFRNT-ELIVPDQHISIQGQNN 371 Query: 255 GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLSPNSVNVESGNVARFT 313 +L++ G Y C A + + D P I S + V G Sbjct: 372 DTLQITAAQKFHSGAYQCFASRKGHTAQDFSIILLEDGTPRIVSSFSERVVNPGEPFSLM 431 Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV-C 372 C A G P P++ W+++ + +Y + DG+TV +N + + + C Sbjct: 432 CAAKGAPPPSITWTLDDEPVVRDSTYKTSQY---TLSDGLTVSHVNVSSPHIRDGGVYRC 488 Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432 A N AGS+ + ++ V R PP I + T C I P I W Sbjct: 489 VARNSAGSAEYQARINV-----RGPPRI-RPMRDMTAVAGRNTYITCRVIGYPYYSIKWL 542 Query: 433 FEGEALIQNHRRNVTNDGTLVLKDLDK-SDSGTYTCVASSRHGKYVWSGALLVDSPINPN 491 +G L NHR+ V +GTL L D+ K +D GTY C + + + + V + P Sbjct: 543 KDGMQLPDNHRQVVFENGTLRLTDVQKGADEGTYLCSVLIQPQVSI-NQTVHVTVKVPPL 601 Query: 492 IHFFRAADVSSLPGPPTKPITHNVT--DTSVTLSWSQNNK---IGSSSILGYQVEVFSRE 546 I F D+ S I V+ D + ++W ++ + GS+S + + + F Sbjct: 602 IQPF---DIPSTSVGKLIYIACVVSSGDMPIRITWHKDGQPIVPGSASGVAIETKDFMSS 658 Query: 547 TLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD-SV 605 T +++ + IA T + LI + F+V+ N + G + V + SV Sbjct: 659 LQITKVTLKHNGNYTCIASNTAATVSWERQLIVTVPPRFVVQPNNQDCIYGKAGVLNCSV 718 Query: 606 TVGDDSNSLWE-GTGVSNSTEYRNNILTDHI 635 +W+ GV N +Y LT I Sbjct: 719 EGYPPPKVMWKHAKGVGNPQQYHPVPLTGRI 749 Score = 56.4 bits (130), Expect = 4e-06 Identities = 51/178 (28%), Positives = 85/178 (47%), Gaps = 27/178 (15%) Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429 I +AV AG K+TV P I++ G + T +K + + PC+++ P P I Sbjct: 1289 IWAAAVTTAGKGNFSSKVTVEPAGKVPAKILSFGGTVTTPWMKEVRL-PCSSVGEPAPTI 1347 Query: 430 AWYFEGE----ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485 W + E + + +R V ++GTLVL+ + DSG YTC A++ G ++V+ Sbjct: 1348 KWTKDSEDSAVPVTSDSQRQVLSNGTLVLRSVKAEDSGYYTCTATNTLG----FDTIIVN 1403 Query: 486 SPINPNIHFFRAADVSSLPGPPTKP-ITHNVTDT-SVTLSWSQNNKIGSSSILGYQVE 541 + PP +P +T + T T S+TL+W + G SSI G+ ++ Sbjct: 1404 LVVQV---------------PPDQPRLTVSTTSTSSITLAWIPGDN-GGSSIRGFVLQ 1445 Score = 43.6 bits (98), Expect = 0.034 Identities = 26/97 (26%), Positives = 44/97 (45%), Gaps = 6/97 (6%) Query: 134 GSPEPNVYWKKNGQ--TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191 G P P + W K+ + + DS+ ++ G LV++ + D+G Y C A N G ++ Sbjct: 1341 GEPAPTIKWTKDSEDSAVPVTSDSQRQVLSNGTLVLRSVKAEDSGYYTCTATNTLGF-DT 1399 Query: 192 AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228 I L + + P P V+ T +S + GD Sbjct: 1400 IIVNLVVQVPP---DQPRLTVSTTSTSSITLAWIPGD 1433 Score = 42.7 bits (96), Expect = 0.059 Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 8/76 (10%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYK----GGVLVVSDTHRSILPAGGLFFLRATHGRV 76 VT + L C + G P+P I+W K V V SD+ R +L + G LR+ Sbjct: 1325 VTTPWMKEVRLPCSSVGEPAPTIKWTKDSEDSAVPVTSDSQRQVL-SNGTLVLRSVKA-- 1381 Query: 77 HSDAGVYWCEATNSYG 92 D+G Y C ATN+ G Sbjct: 1382 -EDSGYYTCTATNTLG 1396 Score = 42.3 bits (95), Expect = 0.078 Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 3/78 (3%) Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAE 275 V C G+P P + W + + +P+ + +VL +G+L L +V D G Y+C A Sbjct: 1333 VRLPCSSVGEPAPTIKWTKDSEDSAVPVTSDSQRQVLSNGTLVLRSVKAEDSGYYTCTAT 1392 Query: 276 NSVGAVSASGYLTVYDPP 293 N++G + L V PP Sbjct: 1393 NTLGFDTIIVNLVVQVPP 1410 >UniRef50_UPI00004DA303 Cluster: UPI00004DA303 related cluster; n=2; Xenopus tropicalis|Rep: UPI00004DA303 UniRef100 entry - Xenopus tropicalis Length = 2690 Score = 170 bits (413), Expect = 2e-40 Identities = 144/460 (31%), Positives = 203/460 (44%), Gaps = 41/460 (8%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 L+C A GSPSP + K G + S + L R S AG Y C A NS Sbjct: 1151 LSCEAEGSPSPVVTSLKDGEPLDSGVWGVAIRGSRLQITRVQQ----SHAGRYRCIAQNS 1206 Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLECLPPRGSPEPNVYWKKNGQ-- 147 ++ L V V F E S+ S + V LEC G+P P + W K+G Sbjct: 1207 ISETH-KDFVLLVQVAPRIFGSEMPSEHSVPEKQEVKLEC-KTEGTPAPQILWFKDGNPL 1264 Query: 148 --TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL- 204 TL+ + + DG LV++ + +D+GRY C+ARN AG ++ + L I P L Sbjct: 1265 DVTLVPNTSGNLTKQDGNFLVLRSVQASDSGRYTCVARNNAG-EDTRVYVLNILGLPVLE 1323 Query: 205 -ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVI 263 E+V A G+SVTF C G PLP + W + N+ + L L++V Sbjct: 1324 RSESTEEVTAIKGASVTFTCEAHGTPLPSLSWEKDGQPLNLQSNLLPNGLGTRLHLESVR 1383 Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPPSIN--LSPNSVNVESGNVARFTCTATGRPE 321 D G YSC A N+ G VS +LTV +PP I P V++ + + CTATG P Sbjct: 1384 ALDSGIYSCIAVNAAGRVSKHFHLTVLEPPRIEGPALPTEVSIIADSPLELACTATGVPT 1443 Query: 322 PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG-- 379 P + W +G R H + TVL I D+ VC A + AG Sbjct: 1444 PEISWEKDG----------RPLSHPDLLTRNGTVLRIERVKAEDA-GIYVCVATSTAGRD 1492 Query: 380 --SSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436 +++VR K+ PP ++ + P + + + V C P P I WY Sbjct: 1493 SRATWVRMKV--------PPSVVGSTEPRSLAVSVGGQLVLECKVEADPPPTIQWYRGDI 1544 Query: 437 ALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHGK 475 L + R V + G V + L SDSG YTC+AS+ G+ Sbjct: 1545 PLQTDGRVQVLSKGRYVQIHSLRPSDSGEYTCIASNPAGR 1584 Score = 139 bits (336), Expect = 5e-31 Identities = 125/481 (25%), Positives = 206/481 (42%), Gaps = 39/481 (8%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I+ + L+ ++A +QP L C++ P P I W K G ++ ++ G +L+ Sbjct: 376 PTIMGEELNSSIAVNQPLLLECQSTAIPPPLITWLKDGRPLLQRPGVQVIDDG--HYLQI 433 Query: 72 THGRVHSDAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130 ++ DAG Y CEA+N G T + N + + P+ +G V +EC+ Sbjct: 434 DQAQLR-DAGRYTCEASNDAGRTEKHYNVIIWAQPMIAGSSNTPKQLMVNKGSLVTMECV 492 Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190 G P P+V W K+G L +G G L I A+ + +GRY C+A NAAG + Sbjct: 493 -VSGKPSPSVTWLKDGYP-LGNGPDLFFQNKGQQLTILKAQPSHSGRYVCVAVNAAGQTD 550 Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGS---SVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247 + + P L +++ + S + T C G P P + W R+ P Sbjct: 551 IKYEVF-VQVPPELPNTQTELLNVSTSLHGTFTITCEATGIPPPVITWFRN-NEALSPRE 608 Query: 248 RVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN-LSPNSVNVE 305 V + G LR+ + + D G Y+C N+ G ++ + PPSI+ N + V Sbjct: 609 NVHLQSGGRVLRITHAQIQDAGHYTCVVTNTAGQAKKDFFVDILVPPSIDGEDDNDLRVP 668 Query: 306 SGNVARFTCTATGRPEPTMFWSVE------GNRTIIFPGMSRDKYHATAVFD--GVTVLT 357 G +C +G P+P + W + G+ +I P S + VF+ T + Sbjct: 669 EGQSVTLSCKVSGHPKPLITWLRDSQPVQSGDEVLISPDGSELHIQSANVFNVGHYTCIA 728 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417 IN + SR+ IV V S + G L +++D +I N P + Sbjct: 729 INSIAER-SRSYIVTVLV----SPTISGPLDDEANED--VIVIVNNPFS----------L 771 Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKY 476 C A+ P P + W GE + + G L + + + DSG YTCV ++ G+ Sbjct: 772 ICEALGFPIPSVTWLKNGEPFKDSDNLRLLPGGHGLQILNAQEEDSGQYTCVVTNEVGEA 831 Query: 477 V 477 + Sbjct: 832 I 832 Score = 138 bits (335), Expect = 6e-31 Identities = 125/465 (26%), Positives = 188/465 (40%), Gaps = 31/465 (6%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFLRATHGRVHS 78 D+T L+C+A G P P + W K G L D H + G + L T S Sbjct: 12 DMTARDGSEVELHCKASGVPRPQVEWTKDGQPLPPGDAHIQLTEGGQVLQLNGTR---LS 68 Query: 79 DAGVYWCEATNSYGT-ARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137 D G Y C A N G + N +H E G TV L C R SP Sbjct: 69 DQGRYQCLAFNHAGQQVKDFNLRVHTPPTIWASNETTEVASLLHG-TVELRC-EARASPV 126 Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196 P + W K+ + ++ SR +GG +L + +D G Y C A N AGT E + L Sbjct: 127 PGITWFKDKRPIV--SSSRATYREGGRSLQLSRVLLSDVGTYTCRATNNAGTAEKSYR-L 183 Query: 197 KIHIKPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254 ++++ P ++ G E V + C G P P + W R+ + G V+VL+ Sbjct: 184 EVYVPPKVVIGEGSEHVTVTANDPLDLSCHATGYPTPTIQWLRNNHSLSHEDG-VEVLNG 242 Query: 255 ---GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVAR 311 L++++ +D GEY C A N+ G+ L V P I + Sbjct: 243 VQGPKLQIESAKSSDSGEYRCVASNTAGSTELQYNLLVNVAPRIVSMMDFATFLVNEQVW 302 Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371 C ATG PEP + W + + + ++ + + +L++ +DS Sbjct: 303 LECNATGVPEPAIMWLKD--QVPVSTAIA-----GLQIMEQGRILSLRAAHVSDS-GIYS 354 Query: 372 CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431 C AVN AG L V PP I N ++ + + C + P P+I W Sbjct: 355 CVAVNPAGEDSHHIALQVFV-----PPTIMGEELNSSIAVNQPLLLECQSTAIPPPLITW 409 Query: 432 YFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGK 475 +G L+Q V +DG L + D+G YTC AS+ G+ Sbjct: 410 LKDGRPLLQRPGVQVIDDGHYLQIDQAQLRDAGRYTCEASNDAGR 454 Score = 132 bits (319), Expect = 6e-29 Identities = 137/472 (29%), Positives = 195/472 (41%), Gaps = 39/472 (8%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFL 69 AP I+ T ++ L C A G P PAI W K V V + I+ G + L Sbjct: 283 APRIVSMMDFATFLVNEQVWLECNATGVPEPAIMWLKDQVPVSTAIAGLQIMEQGRILSL 342 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 RA H SD+G+Y C A N G S + L V V E + A ++LEC Sbjct: 343 RAAH---VSDSGIYSCVAVNPAG-EDSHHIALQVFV-PPTIMGEELNSSIAVNQPLLLEC 397 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189 P P + W K+G+ LL ++ + DG L I A+ DAGRY C A N AG Sbjct: 398 -QSTAIPPPLITWLKDGRPLLQRPGVQV-IDDGHYLQIDQAQLRDAGRYTCEASNDAGRT 455 Query: 190 ESAIATLKIHIKPYLITG----PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 E + I +P +I G P+ ++ GS VT +C V G P P V W + P Sbjct: 456 EKHYNVI-IWAQP-MIAGSSNTPKQLMVNKGSLVTMECVVSGKPSPSVTWLKD----GYP 509 Query: 246 LGRVKVL---DDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-NLSPN 300 LG L + G L + + G Y C A N+ G + V PP + N Sbjct: 510 LGNGPDLFFQNKGQQLTILKAQPSHSGRYVCVAVNAAGQTDIKYEVFVQVPPELPNTQTE 569 Query: 301 SVNVESGNVARF--TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358 +NV + F TC ATG P P + W N + P R+ H + G VL I Sbjct: 570 LLNVSTSLHGTFTITCEATGIPPPVITWF--RNNEALSP---RENVHLQS---GGRVLRI 621 Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418 D+ + C N AG + K D PP I ++ +P Sbjct: 622 THAQIQDAGH-YTCVVTNTAG----QAKKDFFVDILVPPSIDGEDDNDLRVPEGQSVTLS 676 Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVA 469 C P+P+I W + + + ++ DG+ L ++ + + G YTC+A Sbjct: 677 CKVSGHPKPLITWLRDSQPVQSGDEVLISPDGSELHIQSANVFNVGHYTCIA 728 Score = 132 bits (318), Expect = 7e-29 Identities = 122/481 (25%), Positives = 205/481 (42%), Gaps = 39/481 (8%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P + L+V+ + H T+ C A G P P I W++ +S L +GG L Sbjct: 562 ELPNTQTELLNVSTSLHGTFTITCEATGIPPPVITWFRNNE-ALSPRENVHLQSGGR-VL 619 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 R TH ++ DAG Y C TN+ G A+ ++ + + V + + +G +V L C Sbjct: 620 RITHAQI-QDAGHYTCVVTNTAGQAK-KDFFVDILVPPSIDGEDDNDLRVPEGQSVTLSC 677 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189 G P+P + W ++ Q + GD + DG L IQ A + G Y CIA N+ R Sbjct: 678 -KVSGHPKPLITWLRDSQPVQ-SGDEVLISPDGSELHIQSANVFNVGHYTCIAINSIAER 735 Query: 190 ESAIATLKIHIKPYLITGP------EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 S + + + P I+GP EDV+ + + C G P+P V W ++ G Sbjct: 736 -SRSYIVTVLVSP-TISGPLDDEANEDVIVIVNNPFSLICEALGFPIPSVTWLKN-GEPF 792 Query: 244 MPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI------- 295 +++L G L++ N D G+Y+C N VG + + V+ PP I Sbjct: 793 KDSDNLRLLPGGHGLQILNAQEEDSGQYTCVVTNEVGEAIRNYEVKVFIPPVIKRDDPHQ 852 Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355 ++ V + + C + P+PT+ W +G G+ + DG Sbjct: 853 DVGIKEVKTKVNSSLTLQCESQAVPKPTLHWYKDGQLLESSGGVQ-------ILSDG-QE 904 Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415 L + +DS C A N AG + V DD+ +T + + ++ Sbjct: 905 LQLQPIRLSDS-GRYTCVATNVAGEDEKEFYVNVQDDDEEE---LTE--HREVVATNPIS 958 Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHG 474 ++ C P PI+ WY +G+ L + + +G ++ + +G YTC A++ G Sbjct: 959 LY-CDTNAIPPPILTWYKDGQLLSSSDGVLILLEGRILQIPMAHAKHAGKYTCEATNEAG 1017 Query: 475 K 475 + Sbjct: 1018 E 1018 Score = 120 bits (289), Expect = 2e-25 Identities = 122/466 (26%), Positives = 195/466 (41%), Gaps = 34/466 (7%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG-GLFFLRATHGRVHS 78 DV V + P +L C A G P P++ W K G + +LP G GL L A Sbjct: 760 DVIVIVNNPFSLICEALGFPIPSVTWLKNGEPFKDSDNLRLLPGGHGLQILNAQE----E 815 Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK------QSAQGDTVVLECLPP 132 D+G Y C TN G A RN + V + R +P ++ ++ L+C Sbjct: 816 DSGQYTCVVTNEVGEA-IRNYEVKVFIPPVIKRDDPHQDVGIKEVKTKVNSSLTLQC-ES 873 Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192 + P+P ++W K+GQ L G ++ L DG L +Q R +D+GRY C+A N AG E Sbjct: 874 QAVPKPTLHWYKDGQLLESSGGVQI-LSDGQELQLQPIRLSDSGRYTCVATNVAGEDEKE 932 Query: 193 IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL 252 +T +VVA + ++ C P P + W + + G + +L Sbjct: 933 FYVNVQDDDEEELTEHREVVAT--NPISLYCDTNAIPPPILTWYKDGQLLSSSDGVLILL 990 Query: 253 DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP----SINLSPNSVNVESGN 308 + L++ G+Y+CEA N G L V PP ++ V+V Sbjct: 991 EGRILQIPMAHAKHAGKYTCEATNEAGEDRLHYELVVLTPPVMKGEVDELIQEVSVIYNQ 1050 Query: 309 VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368 A C A+G P P++ W + T+ + ++Y + +G T L I+ +D + Sbjct: 1051 TAELHCDASGIPPPSITW-LRNGLTL----STAERYQ--ILNEGKT-LQIHSVQVSDI-D 1101 Query: 369 TIVCSAVNYAGSS---FVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425 + VC A N AG + F ++ R P + + L I V C A +P Sbjct: 1102 SYVCVAENPAGFAERLFTLMVHELSFSSVRCP--VPPHTRDYVLIIGKSIVLSCEAEGSP 1159 Query: 426 EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471 P++ +GE L L + + +S +G Y C+A + Sbjct: 1160 SPVVTSLKDGEPLDSGVWGVAIRGSRLQITRVQQSHAGRYRCIAQN 1205 Score = 116 bits (278), Expect = 5e-24 Identities = 98/324 (30%), Positives = 152/324 (46%), Gaps = 25/324 (7%) Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG----VLVVSDTHRSILPAGGLFF-LR 70 E P + +V Q L C+ G+P+P I W+K G V +V +T ++ G F LR Sbjct: 1228 EMPSEHSVPEKQEVKLECKTEGTPAPQILWFKDGNPLDVTLVPNTSGNLTKQDGNFLVLR 1287 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLEC 129 + SD+G Y C A N+ G +R L++ L R E + +A +G +V C Sbjct: 1288 SVQA---SDSGRYTCVARNNAG-EDTRVYVLNILGLPVLERSESTEEVTAIKGASVTFTC 1343 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189 G+P P++ W+K+GQ L + + + G L ++ R D+G Y CIA NAAG R Sbjct: 1344 -EAHGTPLPSLSWEKDGQPLNLQSNLLPNGL-GTRLHLESVRALDSGIYSCIAVNAAG-R 1400 Query: 190 ESAIATLKIHIKPYLITG---PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 S L + ++P I G P +V S + C G P P++ W + PL Sbjct: 1401 VSKHFHLTV-LEPPRIEGPALPTEVSIIADSPLELACTATGVPTPEISWEKD----GRPL 1455 Query: 247 GRVKVLD-DGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSV 302 +L +G+ LR++ V D G Y C A ++ G S + ++ + PPS+ + P S+ Sbjct: 1456 SHPDLLTRNGTVLRIERVKAEDAGIYVCVATSTAGRDSRATWVRMKVPPSVVGSTEPRSL 1515 Query: 303 NVESGNVARFTCTATGRPEPTMFW 326 V G C P PT+ W Sbjct: 1516 AVSVGGQLVLECKVEADPPPTIQW 1539 Score = 104 bits (249), Expect = 2e-20 Identities = 81/276 (29%), Positives = 131/276 (47%), Gaps = 24/276 (8%) Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75 E +VT + T C A G+P P++ W K G + + ++LP G L R Sbjct: 1326 ESTEEVTAIKGASVTFTCEAHGTPLPSLSWEKDGQPL--NLQSNLLPNGLGTRLHLESVR 1383 Query: 76 VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPES---KQSAQGDTVVLECLPP 132 D+G+Y C A N+ G H+ VL E R+E + + S D+ + Sbjct: 1384 A-LDSGIYSCIAVNAAGRVSKH---FHLTVL-EPPRIEGPALPTEVSIIADSPLELACTA 1438 Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192 G P P + W+K+G+ L + +G L I+ + DAG Y C+A + AG R+S Sbjct: 1439 TGVPTPEISWEKDGRPL---SHPDLLTRNGTVLRIERVKAEDAGIYVCVATSTAG-RDSR 1494 Query: 193 IATLKIHIKPYLI--TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL---G 247 +++ + P ++ T P + G + +C+V DP P + W R G++PL G Sbjct: 1495 ATWVRMKVPPSVVGSTEPRSLAVSVGGQLVLECKVEADPPPTIQWYR----GDIPLQTDG 1550 Query: 248 RVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVS 282 RV+VL G +++ ++ +D GEY+C A N G S Sbjct: 1551 RVQVLSKGRYVQIHSLRPSDSGEYTCIASNPAGRTS 1586 Score = 85.8 bits (203), Expect = 6e-15 Identities = 82/285 (28%), Positives = 115/285 (40%), Gaps = 22/285 (7%) Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV-LDDGS--LRLDNVILA 265 +D+ A+ GS V C+ G P P V W + G +P G + L +G L+L+ L+ Sbjct: 11 QDMTARDGSEVELHCKASGVPRPQVEWTKD--GQPLPPGDAHIQLTEGGQVLQLNGTRLS 68 Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES--GNVARFTCTATGRPEPT 323 D+G Y C A N G L V+ PP+I S + V S C A P P Sbjct: 69 DQGRYQCLAFNHAGQQVKDFNLRVHTPPTIWASNETTEVASLLHGTVELRCEARASPVPG 128 Query: 324 MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383 + W + R I+ SR Y +G L ++ +D T C A N AG++ Sbjct: 129 ITW-FKDKRPIV--SSSRATYR-----EGGRSLQLSRVLLSDV-GTYTCRATNNAGTAEK 179 Query: 384 RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR 443 +L V P +I G + T+ C A P P I W +L Sbjct: 180 SYRLEVYVP---PKVVIGEGSEHVTVTANDPLDLSCHATGYPTPTIQWLRNNHSLSHEDG 236 Query: 444 RNVTN---DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485 V N L ++ SDSG Y CVAS+ G LLV+ Sbjct: 237 VEVLNGVQGPKLQIESAKSSDSGEYRCVASNTAGSTELQYNLLVN 281 Score = 59.3 bits (137), Expect = 6e-07 Identities = 63/242 (26%), Positives = 99/242 (40%), Gaps = 19/242 (7%) Query: 292 PPSINL--SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349 PPSI S + G+ C A+G P P + W+ +G + PG + + Sbjct: 1 PPSIYGAGSLQDMTARDGSEVELHCKASGVPRPQVEWTKDGQP--LPPGDAH-----IQL 53 Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409 +G VL +N T +D + C A N+AG L V + PP I + + + Sbjct: 54 TEGGQVLQLNGTRLSD-QGRYQCLAFNHAGQQVKDFNLRVHT----PPTIWASNETTEVA 108 Query: 410 PIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTC 467 + V C A +P P I W+ + ++ + R G +L L + SD GTYTC Sbjct: 109 SLLHGTVELRCEARASPVPGITWFKDKRPIVSSSRATYREGGRSLQLSRVLLSDVGTYTC 168 Query: 468 VASSRHGKYVWSGALLVDSPINPNIHFFRAAD-VSSLPGPPTKPITHNVTDTSVTLSWSQ 526 A++ G S L V P P + ++ V+ P H + T+ W + Sbjct: 169 RATNNAGTAEKSYRLEVYVP--PKVVIGEGSEHVTVTANDPLDLSCHATGYPTPTIQWLR 226 Query: 527 NN 528 NN Sbjct: 227 NN 228 >UniRef50_Q02246 Cluster: Contactin-2 precursor; n=38; Euteleostomi|Rep: Contactin-2 precursor - Homo sapiens (Human) Length = 1040 Score = 169 bits (412), Expect = 3e-40 Identities = 140/492 (28%), Positives = 209/492 (42%), Gaps = 42/492 (8%) Query: 12 PYIIEQPLDVTV---ARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLF 67 P +QPL V + + L CRA SP RW G + + R L G L Sbjct: 37 PVFEDQPLSVLFPEESTEEQVLLACRARASPPATYRWKMNGTEMKLEPGSRHQLVGGNLV 96 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127 + T + DAGVY C A+N GT SR A L L+E + E + ++ +G V+L Sbjct: 97 IMNPTKAQ---DAGVYQCLASNPVGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVML 153 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD--GGNLVIQDARQTDAGRYQCIARNA 185 C PP P + W N D R H V GNL I +D G Y C+A + Sbjct: 154 PCNPPAHYPGLSYRWLLNEFPNFIPTDGR-HFVSQTTGNLYIARTNASDLGNYSCLATSH 212 Query: 186 A--GTRE--SAIATLKIHIKPYLITGPE-------DVVAQTGSSVTFQCRVGGDPLPDVL 234 T+ S A L + + + P + A G VT +C G+P+P + Sbjct: 213 MDFSTKSVFSKFAQLNLAAEDTRLFAPSIKARFPAETYALVGQQVTLECFAFGNPVPRIK 272 Query: 235 WRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294 WR+ G L + +L++ +V DEG Y CEAENS G + G + V P Sbjct: 273 WRKVDGS----LSPQWTTAEPTLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQAQPE 328 Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354 + + G+ R+ C A G+P PT+ W G P S+++ A + Sbjct: 329 WLKVISDTEADIGSNLRWGCAAAGKPRPTVRWLRNGE-----PLASQNRVEVLAGDLRFS 383 Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK-- 412 L++ D+ C A N G+ + +L V + P P + +P Sbjct: 384 KLSLEDS------GMYQCVAENKHGTIYASAELAVQA----LAPDFRLNPVRRLIPAARG 433 Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472 + PC P+ ++ W E L+ + R VT DGTL+++++ +SD G YTC A + Sbjct: 434 GEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENF 493 Query: 473 HGKYVWSGALLV 484 GK +G L V Sbjct: 494 MGKANSTGILSV 505 Score = 108 bits (259), Expect = 1e-21 Identities = 87/309 (28%), Positives = 136/309 (44%), Gaps = 22/309 (7%) Query: 27 QPATLNCRAGGSPSPAIRWYK--GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYW 84 Q TL C A G+P P I+W K G + T L + F D G Y Sbjct: 255 QQVTLECFAFGNPVPRIKWRKVDGSLSPQWTTAEPTLQIPSVSF---------EDEGTYE 305 Query: 85 CEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK 144 CEA NS G + + A + E+ ++ G + C G P P V W + Sbjct: 306 CEAENSKGRDTVQGRIIVQA--QPEWLKVISDTEADIGSNLRWGCAAA-GKPRPTVRWLR 362 Query: 145 NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL 204 NG+ L +R+ ++ G+L D+G YQC+A N GT ++ + P Sbjct: 363 NGEPLA--SQNRVEVL-AGDLRFSKLSLEDSGMYQCVAENKHGTIYASAELAVQALAPDF 419 Query: 205 ITGPED--VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNV 262 P + A G + C+ P VLW + + RV V DG+L + N+ Sbjct: 420 RLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWSKGTEI-LVNSSRVTVTPDGTLIIRNI 478 Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP-- 320 +DEG+Y+C AEN +G +++G L+V D I L+P+S ++ G+ C A+ P Sbjct: 479 SRSDEGKYTCFAENFMGKANSTGILSVRDATKITLAPSSADINLGDNLTLQCHASHDPTM 538 Query: 321 EPTMFWSVE 329 + T W+++ Sbjct: 539 DLTFTWTLD 547 Score = 107 bits (257), Expect = 2e-21 Identities = 133/491 (27%), Positives = 192/491 (39%), Gaps = 58/491 (11%) Query: 59 SILPAGGLFFLRATHGRVH------SDAGVYWCEATN----SYGTARSRNATLHVAVLRE 108 + +P G F+ T G ++ SD G Y C AT+ S + S+ A L++A E Sbjct: 175 NFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHMDFSTKSVFSKFAQLNLAA--E 232 Query: 109 EFRLE--------PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV 160 + RL P + G V LEC G+P P + W+K +L S Sbjct: 233 DTRLFAPSIKARFPAETYALVGQQVTLECFA-FGNPVPRIKWRKVDGSL-----SPQWTT 286 Query: 161 DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVT 220 L I D G Y+C A N+ G R++ + + +P + D A GS++ Sbjct: 287 AEPTLQIPSVSFEDEGTYECEAENSKG-RDTVQGRIIVQAQPEWLKVISDTEADIGSNLR 345 Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA 280 + C G P P V W R+ G RV+VL G LR + L D G Y C AEN G Sbjct: 346 WGCAAAGKPRPTVRWLRN-GEPLASQNRVEVLA-GDLRFSKLSLEDSGMYQCVAENKHGT 403 Query: 281 VSASGYLTVYD-PPSINLSP--NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337 + AS L V P L+P + G C P+ + WS T I Sbjct: 404 IYASAELAVQALAPDFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWS---KGTEILV 460 Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397 SR T DG L I + ++D C A N+ G + G L+V R Sbjct: 461 NSSR----VTVTPDGT--LIIRNISRSDE-GKYTCFAENFMGKANSTGILSV-----RDA 508 Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL 457 IT PS+ + + C A P + + + + + + G + Sbjct: 509 TKITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWT----LDDFPIDFDKPGGHYRRTN 564 Query: 458 DKSDSGTYTCV-ASSRHG-KYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNV 515 K G T + A RHG KY +VDS R PGPP + ++ Sbjct: 565 VKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRGP-----PGPPGGVVVRDI 619 Query: 516 TDTSVTLSWSQ 526 DT++ LSWS+ Sbjct: 620 GDTTIQLSWSR 630 >UniRef50_UPI0000F34A69 Cluster: UPI0000F34A69 related cluster; n=2; Bos taurus|Rep: UPI0000F34A69 UniRef100 entry - Bos Taurus Length = 4164 Score = 168 bits (409), Expect = 7e-40 Identities = 135/464 (29%), Positives = 207/464 (44%), Gaps = 41/464 (8%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 DV V R L C A GSP P + W K G ++ +S+ GL A G Sbjct: 3276 DVAVVRGSLVFLPCEARGSPLPFVSWVKDGEPLLP---QSLEHGPGLLLEAAEAGH---- 3328 Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139 AG Y C A + G AR + E +PE G + L C RG+P PN Sbjct: 3329 AGTYSCVAVSEAGEARRHFQLTVMDPPYIEDSDQPEELLLTPGTPLELLC-DARGTPTPN 3387 Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLV--IQDARQTDAGRYQCIARNAAGTRESAIATLK 197 + W K+G+ L + D + G V ++ + +DAG Y C+A + AG E + ++ Sbjct: 3388 ITWHKDGRALSWPEDGQ-----GARRVLRVEGVQVSDAGLYTCLAHSPAGEVEKSFR-IR 3441 Query: 198 IHIKPYLIT--GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255 + P +I GP VV + +C V DP P++ W R G + ++G Sbjct: 3442 VQAPPNVIGSHGPRFVVGLAPGQLVLECSVEADPAPEIEWHRE-GVLLQADAHTQFPEEG 3500 Query: 256 S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314 L+L + AD G+YSC A N+ G+ S + ++ V+ PP++N S N + C Sbjct: 3501 RFLQLQALSTADSGDYSCTAHNAAGSTSLAFHVEVHRPPTVNASVNQTTL-------LPC 3553 Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374 A G P+P + W +G + PG +R + +G+ + + D +C A Sbjct: 3554 QADGVPQPLVSWLKDG--VPLDPGSTRWVLAREGLREGLRIQPVLAEDAGH----YLCLA 3607 Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFE 434 N AGS L V PP I GPSN TL + A PC A +P+P++AW+ + Sbjct: 3608 SNPAGSDRQGRDLQVFE-----PPAIAPGPSNLTLTAYTPASLPCEASGSPKPLVAWWKD 3662 Query: 435 GEAL---IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 G+ L +Q + L+L++ DS + CV S+ G+ Sbjct: 3663 GQKLDFRLQQGAYRLLPSNALLLEEPSPQDSALFECVVSNGVGE 3706 Score = 165 bits (401), Expect = 6e-39 Identities = 138/474 (29%), Positives = 201/474 (42%), Gaps = 33/474 (6%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV---VSDTHRSILPAGGL 66 E P I P ++T+ + PA+L C A GSP P + W+K G + + +LP+ L Sbjct: 3624 EPPAIAPGPSNLTLTAYTPASLPCEASGSPKPLVAWWKDGQKLDFRLQQGAYRLLPSNAL 3683 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRN-ATLHVAVLREEFRLEPESKQSAQGDTV 125 + D+ ++ C +N G AR T+HV + + + + A V Sbjct: 3684 LLEEPSP----QDSALFECVVSNGVGEARKLYWVTVHVPPAIADDQTDFTATIMAP---V 3736 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 VL C G P P V W K G L G+ + G L I A GRY C ARNA Sbjct: 3737 VLTC-HSTGVPAPVVSWSKAGTRLGVRGNG-YRVSPSGALEIGQALPIHTGRYTCAARNA 3794 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR---SAGGG 242 AG + L + P + P V A V C G P P + W++ S Sbjct: 3795 AGMAHKHVV-LTVQASPVVKPLPSVVWAVAKEEVLLPCEASGIPRPSIAWQKEGLSVPAA 3853 Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302 N G +VL G LR+ +V D G Y C A+NS G+ L V PP+I + Sbjct: 3854 NPGAG-TQVLPGGQLRIIHVSPEDAGNYFCLAQNSAGSAVRKTRLVVQVPPAIKTGLPDL 3912 Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362 ++ G A CTATG PEP + W +G +S K T G L + +++ Sbjct: 3913 SITEGAHALLPCTATGSPEPKVTWEKDGQP------VSGAKGKFTIQPSGE--LLVKNSE 3964 Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422 D+ T C+A N G + R LT+ + P+ T P +++L + C A Sbjct: 3965 SQDA-GTYTCTAENAVGRARRRVHLTILA-----LPVFTTLPGDRSLRLGDKLWLHCAAR 4018 Query: 423 CTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGK 475 +P P I W + + + G TL + + DSGTY C A +R G+ Sbjct: 4019 GSPTPQIGWTVNNRLVTATEGVSEQDGGSTLQRVAVTREDSGTYVCWAENRVGR 4072 Score = 161 bits (392), Expect = 8e-38 Identities = 139/458 (30%), Positives = 204/458 (44%), Gaps = 31/458 (6%) Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVS-DTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85 Q TL C A G P+P I W K G + + +HR + A L F R G D+G+Y C Sbjct: 1156 QSLTLECDANGFPAPEITWLKNGRQIPAVGSHRLLDGARALHFPRIQEG----DSGLYSC 1211 Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPESKQ-SAQGDTVVLECLPPRGSPEPNVYWKK 144 A N GTA+ R+ L V + E + G LEC G P P V W K Sbjct: 1212 RAENQAGTAQ-RDFDLLVLIPPSVLGAEAAQEVVGLAGAGAELECRT-LGVPTPQVEWTK 1269 Query: 145 NGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY 203 +GQ + F G+ R+ L + G ++ I ++ D G YQC+A + AG +++ L+IH P Sbjct: 1270 DGQPV-FLGEPRVQLQEDGQVLRITNSHLGDEGWYQCVAFSPAG-QQTKDFQLRIHAPPT 1327 Query: 204 LITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG-SLRLD 260 + E +V G V F C G P PD+ W + G +P V G L+L+ Sbjct: 1328 IWGSNETSEVAVMEGHPVWFLCEARGVPTPDITWFKD-GDPLVPSTEVVYTRGGRQLQLE 1386 Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI---NLSPNSVNVESGNVARFTCTAT 317 +D G YSC+A N+VG V + L VY PP+I P V +G C A Sbjct: 1387 RAQGSDAGTYSCKASNAVGVVEKTTRLEVYVPPTIEGTGEGPRVVKAVAGRPLTLECVAR 1446 Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377 G P PT+ W EG P + R + T + G VL++ + S C A + Sbjct: 1447 GYPPPTVSWYHEG-----LPVVDR---NGTWLGAGGGVLSLESLGE-ASGGLYSCVASSP 1497 Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437 AG + + + V P ++ G T + PC A +P P I W G Sbjct: 1498 AGEAVLHYSVEV---QVAPQLLVAEGLGQVTTLVGQSLYLPCYASGSPVPTIQWLQNGHP 1554 Query: 438 LIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474 + +VT++G TL + ++ +G + C A++ G Sbjct: 1555 AEELPGVHVTSEGTTLHIDHVELGHAGLFACQATNEAG 1592 Score = 159 bits (387), Expect = 3e-37 Identities = 145/472 (30%), Positives = 202/472 (42%), Gaps = 29/472 (6%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 V +G P ++ P +VTV+ + A L+C + W + ++ + T R A Sbjct: 483 VVTGPPPQLVPVP-NVTVSPGETAILSCLVLSEAPYNLTWVRDWRVLSASTGRVTQLADL 541 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDT 124 +R T SD G Y C A+NS G R A++ + V + + S++ +QG Sbjct: 542 SLEVRNT---TPSDGGRYQCMASNSNGVTR---ASVWLLVREAPQVSIHTRSQRFSQGME 595 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 V + C G P P++ W + G+ L DSR+ + G L+IQ DAG Y C A N Sbjct: 596 VRVRC-SASGYPAPHISWSREGRAL--QEDSRVRVDAQGTLIIQGVAPEDAGSYSCQAAN 652 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 G E + TL P + V+A G +C G P P V+W R G M Sbjct: 653 EIGRDEETV-TLYYTDPPSVSAVNGVVLAAKGEEAVLECEATGVPPPRVIWYR--GDLEM 709 Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304 L + G LR+ V D G Y+C A N +G SA L V P + P V V Sbjct: 710 ILAPEDSIS-GMLRIPVVRERDAGVYTCRAVNELGDASAEIRLEVGHAPQLLELPQDVTV 768 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 E G A C ATG P PT+ W ++ + G SR A DG L D Sbjct: 769 ELGRSALLACRATGHPLPTITWHRGDDQPLGLRG-SRHSIRA----DGSLHL---DQALL 820 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTV-TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423 + C N AGS +L V R P T+ +N+ +P A PC A Sbjct: 821 EDAGRYSCVVSNTAGSHHRDVQLVVQVKVPPRIQPTATHHITNEGVP----ASLPCVASG 876 Query: 424 TPEPIIAWYFEGEALI-QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 P P I W E AL ++ NV+ DGTLV+ D+G Y C A++ G Sbjct: 877 VPTPTITWTKETNALASRDPHYNVSKDGTLVIPRPSVQDAGAYVCTATNAVG 928 Score = 159 bits (387), Expect = 3e-37 Identities = 144/501 (28%), Positives = 203/501 (40%), Gaps = 47/501 (9%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 EAP + ++ + C A G P+P I W + G + D+ + G L Sbjct: 577 EAPQVSIHTRSQRFSQGMEVRVRCSASGYPAPHISWSREGRALQEDSRVRVDAQGTLII- 635 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 G DAG Y C+A N G TL+ + +A+G+ VLEC Sbjct: 636 ---QGVAPEDAGSYSCQAANEIGRDEE-TVTLYYTDPPSVSAVNGVVL-AAKGEEAVLEC 690 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189 G P P V W + ++ + + G L I R+ DAG Y C A N G Sbjct: 691 -EATGVPPPRVIWYRGDLEMILAPEDSI----SGMLRIPVVRERDAGVYTCRAVNELGDA 745 Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-- 247 + I L++ P L+ P+DV + G S CR G PLP + W R G + PLG Sbjct: 746 SAEIR-LEVGHAPQLLELPQDVTVELGRSALLACRATGHPLPTITWHR---GDDQPLGLR 801 Query: 248 --RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PPSINLSPNSVN 303 R + DGSL LD +L D G YSC N+ G+ L V PP I + Sbjct: 802 GSRHSIRADGSLHLDQALLEDAGRYSCVVSNTAGSHHRDVQLVVQVKVPPRIQPTATHHI 861 Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363 G A C A+G P PT+ W+ E N SRD ++ + DG L I Sbjct: 862 TNEGVPASLPCVASGVPTPTITWTKETNALA-----SRDPHYNVSK-DGT--LVIPRPSV 913 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSD-----DDR-----PPPIITNGPSNQTLPIKS 413 D+ VC+A N G S +L+V + D + P I+ NG P++ Sbjct: 914 QDA-GAYVCTATNAVGFSSQEMRLSVNMEPGFLLDPKHGATAKPRILVNGSHEADKPLRV 972 Query: 414 MA------VFPCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDLDKSDSGTYT 466 A C A +P P++ W + ++ R ++ G+L L SDSG Y Sbjct: 973 TAKAGDEVTLDCEAQGSPPPLVTWTKDSRHMLPITDRHHLLPPGSLHLAQAQVSDSGLYE 1032 Query: 467 CVASSRHGKYVWSGALLVDSP 487 C AS+ G L V P Sbjct: 1033 CTASNPAGSATQYYILRVQVP 1053 Score = 158 bits (383), Expect = 1e-36 Identities = 133/457 (29%), Positives = 199/457 (43%), Gaps = 34/457 (7%) Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82 + + PA L C P+ + WY+G + + S+L G + + DAG Sbjct: 2633 IVENNPAYLYCDTNAVPAAELTWYRGDRPLSIEDGVSVLQGGRVLQIPLVRAE---DAGR 2689 Query: 83 YWCEATNSYGTARSRNATLHVA---VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139 Y C+A+N G L + +L E L E +A TV L C P G+P P Sbjct: 2690 YSCKASNEVGEDWLHYELLVLTPPVILGETEELVEEVTVNANS-TVSLHC-PVLGNPAPT 2747 Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKI 198 + W +NG L F R+ +++ G ++ + A DA Y C+A N AG+ E + TL++ Sbjct: 2748 ISWLQNG--LPFSPSPRLQVLENGRILQVSTAEVADAASYMCVAENPAGSTEK-LFTLRV 2804 Query: 199 HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-- 256 +P L PE + A SSV+ C V P P+V W + G + LG L G+ Sbjct: 2805 QGEPGL--NPEQITATLNSSVSLPCDVRAHPSPEVTWYKD--GWTLSLGEEIFLLPGTHT 2860 Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316 L+L V L D G Y CEA N+ G L+V P + + + V V +G+ A +C Sbjct: 2861 LQLTRVQLLDSGMYICEALNAAGRDHKLVQLSVLAPGAPSRPQDVVLVSAGDKAVLSCET 2920 Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376 PEPT+ W +G + ++ P ++ A G L I D +D + C N Sbjct: 2921 DAFPEPTVAWQKDG-QPLVLP----ERIQALL---GGQRLEIQDAQVSD-KGLYSCRVSN 2971 Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK-SMAVFPCTAICTPEPIIAWYFEG 435 AG + LTV + PP N + + S V C P P + W + Sbjct: 2972 AAGEAMRAFSLTV-----QVPPTFENPETEMVSRVAGSPLVLSCDVTGVPAPAVTWLKDR 3026 Query: 436 EALIQNHRRN-VTNDGTLVLKDLDKSDSGTYTCVASS 471 + + R V+ G L L L +GTYTCVA + Sbjct: 3027 MPVESSMARGVVSRGGRLQLSHLQPDQAGTYTCVAEN 3063 Score = 157 bits (382), Expect = 1e-36 Identities = 127/472 (26%), Positives = 193/472 (40%), Gaps = 24/472 (5%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPA 63 +VT P I + D T P L C + G P+P + W K G L V + P+ Sbjct: 3712 WVTVHVPPAIADDQTDFTATIMAPVVLTCHSTGVPAPVVSWSKAGTRLGVRGNGYRVSPS 3771 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123 G L +A +H+ G Y C A N+ G A ++ L V L P + + Sbjct: 3772 GALEIGQALP--IHT--GRYTCAARNAAGMAH-KHVVLTVQASPVVKPL-PSVVWAVAKE 3825 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182 V+L C G P P++ W+K G ++ + + ++ GG L I DAG Y C+A Sbjct: 3826 EVLLPC-EASGIPRPSIAWQKEGLSVPAANPGAGTQVLPGGQLRIIHVSPEDAGNYFCLA 3884 Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242 +N+AG+ L + + P + TG D+ G+ C G P P V W + Sbjct: 3885 QNSAGSAVRK-TRLVVQVPPAIKTGLPDLSITEGAHALLPCTATGSPEPKVTWEKDGQPV 3943 Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302 + G+ + G L + N D G Y+C AEN+VG +LT+ P P Sbjct: 3944 SGAKGKFTIQPSGELLVKNSESQDAGTYTCTAENAVGRARRRVHLTILALPVFTTLPGDR 4003 Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362 ++ G+ C A G P P + W+V G+S DG + L Sbjct: 4004 SLRLGDKLWLHCAARGSPTPQIGWTVNNRLVTATEGVSEQ--------DGGSTLQRVAVT 4055 Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422 + DS T VC A N G V+ + P+ P + T+ C A Sbjct: 4056 REDS-GTYVCWAENRVGR-----VQAVSFVHVKGVPVFQVKPQDVTVRSGDSVALRCQAS 4109 Query: 423 CTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 P P + W G+ + + R DG+L L+ ++ D+G Y CVA + G Sbjct: 4110 GEPAPTMEWLRAGQPVRASQRLQTLPDGSLWLERVEARDAGPYECVAHNLLG 4161 Score = 157 bits (380), Expect = 2e-36 Identities = 139/469 (29%), Positives = 216/469 (46%), Gaps = 40/469 (8%) Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG--VLVVSDTHRSILPAGGLFFLRATH 73 ++PL VT TL+C A GSP P + W K +L ++D H +LP G L +A Sbjct: 967 DKPLRVTAKAGDEVTLDCEAQGSPPPLVTWTKDSRHMLPITDRHH-LLPPGSLHLAQAQ- 1024 Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133 SD+G+Y C A+N G+A ++ L V V + + P + G+ V L C+ Sbjct: 1025 ---VSDSGLYECTASNPAGSA-TQYYILRVQV-PPQVQPGPRVLKVLVGEAVDLNCV-AE 1078 Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193 GSPEP V W K+G L +G G++ + + AG Y+C A ++AG ++ Sbjct: 1079 GSPEPRVTWSKDGVALRGEGPE-------GSVHFAAIQTSHAGTYRCEASSSAGV-DAWE 1130 Query: 194 ATLKIHIKPYLITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP-LGRVK 250 L++ + P L +V G S+T +C G P P++ W ++ G +P +G + Sbjct: 1131 LDLRVLVPPSLREDGRRANVSGMAGQSLTLECDANGFPAPEITWLKN--GRQIPAVGSHR 1188 Query: 251 VLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE--SG 307 +LD +L + D G YSC AEN G L V PPS+ + + V +G Sbjct: 1189 LLDGARALHFPRIQEGDSGLYSCRAENQAGTAQRDFDLLVLIPPSVLGAEAAQEVVGLAG 1248 Query: 308 NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367 A C G P P + W+ +G +F G R + DG VL I ++ D Sbjct: 1249 AGAELECRTLGVPTPQVEWTKDGQP--VFLGEPRVQLQE----DG-QVLRITNSHLGD-E 1300 Query: 368 NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPE 426 C A + AG +L + + PP I + +++ ++ V F C A P Sbjct: 1301 GWYQCVAFSPAGQQTKDFQLRIHA----PPTIWGSNETSEVAVMEGHPVWFLCEARGVPT 1356 Query: 427 PIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474 P I W+ +G+ L+ + T G L L+ SD+GTY+C AS+ G Sbjct: 1357 PDITWFKDGDPLVPSTEVVYTRGGRQLQLERAQGSDAGTYSCKASNAVG 1405 Score = 156 bits (378), Expect = 4e-36 Identities = 122/463 (26%), Positives = 196/463 (42%), Gaps = 18/463 (3%) Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74 + +P V + +Q L C+A G P P + W K GV + + R +L GL Sbjct: 3535 VHRPPTVNASVNQTTLLPCQADGVPQPLVSWLKDGVPLDPGSTRWVLAREGLREGLRIQP 3594 Query: 75 RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRG 134 + DAG Y C A+N G+ R + L V P + L C G Sbjct: 3595 VLAEDAGHYLCLASNPAGSDR-QGRDLQVFE-PPAIAPGPSNLTLTAYTPASLPC-EASG 3651 Query: 135 SPEPNVYWKKNGQTLLFD-GDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193 SP+P V W K+GQ L F L+ L++++ D+ ++C+ N G + Sbjct: 3652 SPKPLVAWWKDGQKLDFRLQQGAYRLLPSNALLLEEPSPQDSALFECVVSNGVGEARK-L 3710 Query: 194 ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD 253 + +H+ P + D A + V C G P P V W ++ + +V Sbjct: 3711 YWVTVHVPPAIADDQTDFTATIMAPVVLTCHSTGVPAPVVSWSKAGTRLGVRGNGYRVSP 3770 Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313 G+L + + G Y+C A N+ G LTV P + P+ V + Sbjct: 3771 SGALEIGQALPIHTGRYTCAARNAAGMAHKHVVLTVQASPVVKPLPSVVWAVAKEEVLLP 3830 Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373 C A+G P P++ W EG + P + T V G + I+ D+ N C Sbjct: 3831 CEASGIPRPSIAWQKEG---LSVPAANPGA--GTQVLPGGQLRIIH-VSPEDAGNYF-CL 3883 Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF 433 A N AGS+ + +L V + PP I G + ++ + A+ PCTA +PEP + W Sbjct: 3884 AQNSAGSAVRKTRLVV-----QVPPAIKTGLPDLSITEGAHALLPCTATGSPEPKVTWEK 3938 Query: 434 EGEALI-QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 +G+ + + + G L++K+ + D+GTYTC A + G+ Sbjct: 3939 DGQPVSGAKGKFTIQPSGELLVKNSESQDAGTYTCTAENAVGR 3981 Score = 154 bits (373), Expect = 2e-35 Identities = 145/480 (30%), Positives = 209/480 (43%), Gaps = 45/480 (9%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P + P + V + LNC A GSP P + W K GV + R P G + F Sbjct: 1054 PQVQPGPRVLKVLVGEAVDLNCVAEGSPEPRVTWSKDGVAL-----RGEGPEGSVHFAAI 1108 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEPESKQSAQGDTVVLE 128 S AG Y CEA++S G + L V V LRE+ R S + G ++ LE Sbjct: 1109 Q----TSHAGTYRCEASSSAG-VDAWELDLRVLVPPSLREDGRRANVSGMA--GQSLTLE 1161 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAG 187 C G P P + W KNG+ + G R L+DG L ++ D+G Y C A N AG Sbjct: 1162 C-DANGFPAPEITWLKNGRQIPAVGSHR--LLDGARALHFPRIQEGDSGLYSCRAENQAG 1218 Query: 188 TRESAIATLKIHIKPYLI--TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 T + L + I P ++ ++VV G+ +CR G P P V W + + Sbjct: 1219 TAQRDF-DLLVLIPPSVLGAEAAQEVVGLAGAGAELECRTLGVPTPQVEWTKDGQPVFLG 1277 Query: 246 LGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSV 302 RV++ +DG LR+ N L DEG Y C A + G + L ++ PP+I + + V Sbjct: 1278 EPRVQLQEDGQVLRITNSHLGDEGWYQCVAFSPAGQQTKDFQLRIHAPPTIWGSNETSEV 1337 Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362 V G+ F C A G P P + W +G+ + P G L + Sbjct: 1338 AVMEGHPVWFLCEARGVPTPDITWFKDGDPLV--PSTE------VVYTRGGRQLQLERAQ 1389 Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422 +D+ T C A N G +L V PP I G + +K++A P T Sbjct: 1390 GSDA-GTYSCKASNAVGVVEKTTRLEVYV----PPTIEGTGEGPRV--VKAVAGRPLTLE 1442 Query: 423 CT----PEPIIAWYFEGEALI-QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477 C P P ++WY EG ++ +N G L L+ L ++ G Y+CVASS G+ V Sbjct: 1443 CVARGYPPPTVSWYHEGLPVVDRNGTWLGAGGGVLSLESLGEASGGLYSCVASSPAGEAV 1502 Score = 152 bits (368), Expect = 6e-35 Identities = 139/490 (28%), Positives = 209/490 (42%), Gaps = 37/490 (7%) Query: 10 EAPYIIEQPLDVTVAR--HQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67 + P E P V+R P L+C G P+PA+ W K + V S R ++ GG Sbjct: 2985 QVPPTFENPETEMVSRVAGSPLVLSCDVTGVPAPAVTWLKDRMPVESSMARGVVSRGGR- 3043 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127 L+ +H + AG Y C A N+ A + R + + +G V L Sbjct: 3044 -LQLSHLQP-DQAGTYTCVAENAQAEAHKDFVVAVLVAPRIQSSGTTQEHSVLEGQDVQL 3101 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFD-GDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186 +C G P P V W K+G L G ++G +LV++D R +D+G Y C+ARNAA Sbjct: 3102 DC-EVDGQPPPYVVWLKDGSPLDESVGPYLWFYLNGSSLVLKDLRASDSGAYTCVARNAA 3160 Query: 187 GTRESAIATLKIHIKPYLITGPE---DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 G ++ + T+ + + P + GPE +V + G V+ C V G P V W + G Sbjct: 3161 G-EDAKLYTVNVLVPPTIEQGPEGAGTLVHRLGDLVSMACPVRGSPPIHVSWLKD--GLP 3217 Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS--PNS 301 +PL L L V LAD G ++C A + G + L V PP + + N Sbjct: 3218 LPLSHRTHLHSSGRTL-RVQLADSGTFTCVAASPAGVANRHFILQVLVPPVLEPAEFQND 3276 Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361 V V G++ C A G P P + W +G P + + H + + + Sbjct: 3277 VAVVRGSLVFLPCEARGSPLPFVSWVKDGE-----PLLPQSLEHGPGL--------LLEA 3323 Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII--TNGPSNQTLPIKSMAVFPC 419 + T C AV+ AG + +LTV PP I ++ P L + C Sbjct: 3324 AEAGHAGTYSCVAVSEAGEARRHFQLTVMD-----PPYIEDSDQPEELLLTPGTPLELLC 3378 Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479 A TP P I W+ +G AL L ++ + SD+G YTC+A S G+ S Sbjct: 3379 DARGTPTPNITWHKDGRALSWPEDGQGAR-RVLRVEGVQVSDAGLYTCLAHSPAGEVEKS 3437 Query: 480 GALLVDSPIN 489 + V +P N Sbjct: 3438 FRIRVQAPPN 3447 Score = 142 bits (344), Expect = 5e-32 Identities = 131/464 (28%), Positives = 196/464 (42%), Gaps = 30/464 (6%) Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77 P +T + +L C PSP + WYK G + +LP G L+ T ++ Sbjct: 2812 PEQITATLNSSVSLPCDVRAHPSPEVTWYKDGWTLSLGEEIFLLP--GTHTLQLTRVQL- 2868 Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDTVVLECLPPRGSP 136 D+G+Y CEA N+ G + ++VL P+ GD VL C P Sbjct: 2869 LDSGMYICEALNAAGRDHK---LVQLSVLAPGAPSRPQDVVLVSAGDKAVLSC-ETDAFP 2924 Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196 EP V W+K+GQ L+ + L+ G L IQDA+ +D G Y C NAAG A + L Sbjct: 2925 EPTVAWQKDGQPLVLP-ERIQALLGGQRLEIQDAQVSDKGLYSCRVSNAAGEAMRAFS-L 2982 Query: 197 KIHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255 + + P ++V++ GS + C V G P P V W + + R V G Sbjct: 2983 TVQVPPTFENPETEMVSRVAGSPLVLSCDVTGVPAPAVTWLKDRMPVESSMARGVVSRGG 3042 Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV--NVESGNVARFT 313 L+L ++ G Y+C AEN+ + V P I S + +V G + Sbjct: 3043 RLQLSHLQPDQAGTYTCVAENAQAEAHKDFVVAVLVAPRIQSSGTTQEHSVLEGQDVQLD 3102 Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373 C G+P P + W +G+ G Y +G + L + D +DS C Sbjct: 3103 CEVDGQPPPYVVWLKDGSPLDESVGPYLWFY-----LNGSS-LVLKDLRASDS-GAYTCV 3155 Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ-TLP--IKSMAVFPCTAICTPEPIIA 430 A N AG + V PP I GP TL + + C +P ++ Sbjct: 3156 ARNAAGEDAKLYTVNVLV-----PPTIEQGPEGAGTLVHRLGDLVSMACPVRGSPPIHVS 3210 Query: 431 WYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 W +G L +HR ++ + G + L +DSGT+TCVA+S G Sbjct: 3211 WLKDGLPLPLSHRTHLHSSGRTLRVQL--ADSGTFTCVAASPAG 3252 Score = 141 bits (341), Expect = 1e-31 Identities = 134/477 (28%), Positives = 205/477 (42%), Gaps = 35/477 (7%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 V GE ++E+ VTV + +L+C G+P+P I W + G+ +L G Sbjct: 2714 VILGETEELVEE---VTVNANSTVSLHCPVLGNPAPTISWLQNGLPFSPSPRLQVLENGR 2770 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 + L+ + V +DA Y C A N G+ + TL V + E L PE + +V Sbjct: 2771 I--LQVSTAEV-ADAASYMCVAENPAGST-EKLFTLRV---QGEPGLNPEQITATLNSSV 2823 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 L C R P P V W K+G TL G+ L L + + D+G Y C A NA Sbjct: 2824 SLPC-DVRAHPSPEVTWYKDGWTLSL-GEEIFLLPGTHTLQLTRVQLLDSGMYICEALNA 2881 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 AG R+ + L + + P + P+DVV G C P P V W++ + Sbjct: 2882 AG-RDHKLVQLSV-LAPGAPSRPQDVVLVSAGDKAVLSCETDAFPEPTVAWQKDGQPLVL 2939 Query: 245 PLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-NLSPNSV 302 P R++ L G L + + ++D+G YSC N+ G + LTV PP+ N V Sbjct: 2940 P-ERIQALLGGQRLEIQDAQVSDKGLYSCRVSNAAGEAMRAFSLTVQVPPTFENPETEMV 2998 Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362 + +G+ +C TG P P + W + R + M+R G L+ D Sbjct: 2999 SRVAGSPLVLSCDVTGVPAPAVTWLKD--RMPVESSMAR----GVVSRGGRLQLSHLQPD 3052 Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTA 421 + + + +A A FV L P I ++G + + ++ V C Sbjct: 3053 QAGTYTCVAENAQAEAHKDFVVAVLVA-------PRIQSSGTTQEHSVLEGQDVQLDCEV 3105 Query: 422 ICTPEPIIAWYFEGEALIQN---HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 P P + W +G L ++ + N +LVLKDL SDSG YTCVA + G+ Sbjct: 3106 DGQPPPYVVWLKDGSPLDESVGPYLWFYLNGSSLVLKDLRASDSGAYTCVARNAAGE 3162 Score = 140 bits (340), Expect = 2e-31 Identities = 130/465 (27%), Positives = 186/465 (40%), Gaps = 37/465 (7%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 L C P+P I W++ GVL+ +D H G L+A +D+G Y C A N+ Sbjct: 3467 LECSVEADPAPEIEWHREGVLLQADAHTQFPEEGRFLQLQALST---ADSGDYSCTAHNA 3523 Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150 G S + HV V R P + ++ T +L C G P+P V W K+G L Sbjct: 3524 AG---STSLAFHVEVHR------PPTVNASVNQTTLLPCQAD-GVPQPLVSWLKDGVPL- 3572 Query: 151 FDGDSRMHLVDGG---NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG 207 G +R L G L IQ DAG Y C+A N AG+ L++ P + G Sbjct: 3573 DPGSTRWVLAREGLREGLRIQPVLAEDAGHYLCLASNPAGSDRQG-RDLQVFEPPAIAPG 3631 Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL--GRVKVLDDGSLRLDNVILA 265 P ++ + + C G P P V W + + L G ++L +L L+ Sbjct: 3632 PSNLTLTAYTPASLPCEASGSPKPLVAWWKDGQKLDFRLQQGAYRLLPSNALLLEEPSPQ 3691 Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325 D + C N VG ++TV+ PP+I TC +TG P P + Sbjct: 3692 DSALFECVVSNGVGEARKLYWVTVHVPPAIADDQTDFTATIMAPVVLTCHSTGVPAPVVS 3751 Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385 WS G R G+ + Y + G + + R T C+A N AG + Sbjct: 3752 WSKAGTRL----GVRGNGYRVSP--SGALEIG-QALPIHTGRYT--CAARNAAGMAHKHV 3802 Query: 386 KLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG---EALIQNH 442 LTV + P++ PS K + PC A P P IAW EG A Sbjct: 3803 VLTVQAS-----PVVKPLPSVVWAVAKEEVLLPCEASGIPRPSIAWQKEGLSVPAANPGA 3857 Query: 443 RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 V G L + + D+G Y C+A + G V L+V P Sbjct: 3858 GTQVLPGGQLRIIHVSPEDAGNYFCLAQNSAGSAVRKTRLVVQVP 3902 Score = 136 bits (330), Expect = 3e-30 Identities = 137/489 (28%), Positives = 203/489 (41%), Gaps = 59/489 (12%) Query: 28 PATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86 PA+L C A G P+P I W K L D H ++ G L R + DAG Y C Sbjct: 867 PASLPCVASGVPTPTITWTKETNALASRDPHYNVSKDGTLVIPRPSV----QDAGAYVCT 922 Query: 87 ATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---------------------GDTV 125 ATN+ G + S+ L V + F L+P+ +A+ GD V Sbjct: 923 ATNAVGFS-SQEMRLSVN-MEPGFLLDPKHGATAKPRILVNGSHEADKPLRVTAKAGDEV 980 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 L+C +GSP P V W K+ + +L D R HL+ G+L + A+ +D+G Y+C A N Sbjct: 981 TLDC-EAQGSPPPLVTWTKDSRHMLPITD-RHHLLPPGSLHLAQAQVSDSGLYECTASNP 1038 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS--AGGGN 243 AG+ + L++ + P + GP + G +V C G P P V W + A G Sbjct: 1039 AGSA-TQYYILRVQVPPQVQPGPRVLKVLVGEAVDLNCVAEGSPEPRVTWSKDGVALRGE 1097 Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303 P +GS+ + + G Y CEA +S G + L V PPS+ N Sbjct: 1098 GP--------EGSVHFAAIQTSHAGTYRCEASSSAGVDAWELDLRVLVPPSLREDGRRAN 1149 Query: 304 VE--SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361 V +G C A G P P + W G R I G R + DG L Sbjct: 1150 VSGMAGQSLTLECDANGFPAPEITWLKNG-RQIPAVGSHR-------LLDGARALHFPRI 1201 Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM-AVFPCT 420 + DS C A N AG++ L V PP ++ + + + + A C Sbjct: 1202 QEGDS-GLYSCRAENQAGTAQRDFDLLVLI----PPSVLGAEAAQEVVGLAGAGAELECR 1256 Query: 421 AICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLV-LKDLDKSDSGTYTCVASSRHGKYVW 478 + P P + W +G+ + R + DG ++ + + D G Y CVA S G+ Sbjct: 1257 TLGVPTPQVEWTKDGQPVFLGEPRVQLQEDGQVLRITNSHLGDEGWYQCVAFSPAGQQTK 1316 Query: 479 SGALLVDSP 487 L + +P Sbjct: 1317 DFQLRIHAP 1325 Score = 134 bits (324), Expect = 1e-29 Identities = 125/453 (27%), Positives = 191/453 (42%), Gaps = 32/453 (7%) Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88 A L CR G P+P + W K G V R L G LR T+ + D G Y C A Sbjct: 1251 AELECRTLGVPTPQVEWTKDGQPVFLGEPRVQLQEDGQV-LRITNSHL-GDEGWYQCVAF 1308 Query: 89 NSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLECLPPRGSPEPNVYWKKNGQ 147 + G ++++ L + + S+ + +G V C RG P P++ W K+G Sbjct: 1309 SPAGQ-QTKDFQLRIHAPPTIWGSNETSEVAVMEGHPVWFLC-EARGVPTPDITWFKDGD 1366 Query: 148 TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI-- 205 L+ ++ G L ++ A+ +DAG Y C A NA G E L++++ P + Sbjct: 1367 PLV-PSTEVVYTRGGRQLQLERAQGSDAGTYSCKASNAVGVVEKT-TRLEVYVPPTIEGT 1424 Query: 206 -TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264 GP V A G +T +C G P P V W G G L L+++ Sbjct: 1425 GEGPRVVKAVAGRPLTLECVARGYPPPTVSWYHEGLPVVDRNGTWLGAGGGVLSLESLGE 1484 Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES--GNVARFTCTATGRPEP 322 A G YSC A + G + V P + ++ V + G C A+G P P Sbjct: 1485 ASGGLYSCVASSPAGEAVLHYSVEVQVAPQLLVAEGLGQVTTLVGQSLYLPCYASGSPVP 1544 Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382 T+ W G+ PG+ H T+ +G T L I+ + + C A N AG++ Sbjct: 1545 TIQWLQNGHPAEELPGV-----HVTS--EGTT-LHIDHVELGHA-GLFACQATNEAGTAA 1595 Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH 442 +L+V P ++ G N T P C P P + W+ +G AL Sbjct: 1596 AEVELSV----HELPSVVIVGGENITAPFLQPVTLRCAGTGVPTPSLRWWKDGVAL---- 1647 Query: 443 RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 + G+L ++ +D D GTYTCVA++ G+ Sbjct: 1648 ---AASGGSLQIEKVDLKDEGTYTCVATNLAGE 1677 Score = 132 bits (320), Expect = 4e-29 Identities = 120/466 (25%), Positives = 193/466 (41%), Gaps = 28/466 (6%) Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDTVVLECLPPRGSP 136 ++ G Y C A + GT R++ + V +L P + G+T +L CL +P Sbjct: 460 AEEGTYECTAVSRAGTGRAKT---QIVVTGPPPQLVPVPNVTVSPGETAILSCLVLSEAP 516 Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196 N+ W ++ + L L D +L +++ +D GRYQC+A N+ G +++ L Sbjct: 517 Y-NLTWVRDWRVLSASTGRVTQLADL-SLEVRNTTPSDGGRYQCMASNSNGVTRASVWLL 574 Query: 197 KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS 256 + P + G V +C G P P + W R G RV+V G+ Sbjct: 575 -VREAPQVSIHTRSQRFSQGMEVRVRCSASGYPAPHISWSRE-GRALQEDSRVRVDAQGT 632 Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316 L + V D G YSC+A N +G + L DPPS++ V G A C A Sbjct: 633 LIIQGVAPEDAGSYSCQAANEIGRDEETVTLYYTDPPSVSAVNGVVLAAKGEEAVLECEA 692 Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376 TG P P + W I+ P S G+ L I + D+ C AVN Sbjct: 693 TGVPPPRVIWYRGDLEMILAPEDS---------ISGM--LRIPVVRERDA-GVYTCRAVN 740 Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF-EG 435 G + +L V P + P + T+ + A+ C A P P I W+ + Sbjct: 741 ELGDASAEIRLEVGH-----APQLLELPQDVTVELGRSALLACRATGHPLPTITWHRGDD 795 Query: 436 EAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHF 494 + L ++ R ++ DG+L L D+G Y+CV S+ G + L+V + P I Sbjct: 796 QPLGLRGSRHSIRADGSLHLDQALLEDAGRYSCVVSNTAGSHHRDVQLVVQVKVPPRIQP 855 Query: 495 FRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQV 540 +++ P + P + T T++W++ +S Y V Sbjct: 856 TATHHITNEGVPASLPCVASGVPTP-TITWTKETNALASRDPHYNV 900 Score = 132 bits (320), Expect = 4e-29 Identities = 133/508 (26%), Positives = 197/508 (38%), Gaps = 53/508 (10%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80 V A+ + A L C A G P P + WY+G + ++ SI G+ + R DA Sbjct: 678 VLAAKGEEAVLECEATGVPPPRVIWYRGDLEMILAPEDSI---SGMLRIPVVRER---DA 731 Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140 GVY C A N G A S L V + L P+ G + +L C G P P + Sbjct: 732 GVYTCRAVNELGDA-SAEIRLEVGHAPQLLEL-PQDVTVELGRSALLACRAT-GHPLPTI 788 Query: 141 YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA-TLKIH 199 W + L SR + G+L + A DAGRY C+ N AG+ + +++ Sbjct: 789 TWHRGDDQPLGLRGSRHSIRADGSLHLDQALLEDAGRYSCVVSNTAGSHHRDVQLVVQVK 848 Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL 259 + P + + G + C G P P + W + V DG+L + Sbjct: 849 VPPRIQPTATHHITNEGVPASLPCVASGVPTPTITWTKETNALASRDPHYNVSKDGTLVI 908 Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS------------------ 301 + D G Y C A N+VG S L+V P L P Sbjct: 909 PRPSVQDAGAYVCTATNAVGFSSQEMRLSVNMEPGFLLDPKHGATAKPRILVNGSHEADK 968 Query: 302 ---VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358 V ++G+ C A G P P + W+ + + D++H L + Sbjct: 969 PLRVTAKAGDEVTLDCEAQGSPPPLVTWTKDSRHMLPIT----DRHHLLPPGS----LHL 1020 Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418 +DS C+A N AGS+ L V + PP + GP + + Sbjct: 1021 AQAQVSDS-GLYECTASNPAGSATQYYILRV-----QVPPQVQPGPRVLKVLVGEAVDLN 1074 Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVW 478 C A +PEP + W +G AL R +G++ + S +GTY C ASS G W Sbjct: 1075 CVAEGSPEPRVTWSKDGVAL-----RGEGPEGSVHFAAIQTSHAGTYRCEASSSAGVDAW 1129 Query: 479 SGALLVDSPINPNI-HFFRAADVSSLPG 505 L V P P++ R A+VS + G Sbjct: 1130 ELDLRVLVP--PSLREDGRRANVSGMAG 1155 Score = 125 bits (302), Expect = 6e-27 Identities = 84/265 (31%), Positives = 125/265 (47%), Gaps = 13/265 (4%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 D+++ A L C A GSP P + W K G V + + G ++ + + D Sbjct: 3911 DLSITEGAHALLPCTATGSPEPKVTWEKDGQPVSGAKGKFTIQPSGELLVKNSESQ---D 3967 Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLR-EEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138 AG Y C A N+ G AR R +H+ +L F P + GD + L C RGSP P Sbjct: 3968 AGTYTCTAENAVGRARRR---VHLTILALPVFTTLPGDRSLRLGDKLWLHCAA-RGSPTP 4023 Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA-RQTDAGRYQCIARNAAGTRESAIATLK 197 + W N + L + DGG+ + + A + D+G Y C A N G R A++ + Sbjct: 4024 QIGWTVNNR--LVTATEGVSEQDGGSTLQRVAVTREDSGTYVCWAENRVG-RVQAVSFVH 4080 Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257 + P P+DV ++G SV +C+ G+P P + W R AG R++ L DGSL Sbjct: 4081 VKGVPVFQVKPQDVTVRSGDSVALRCQASGEPAPTMEWLR-AGQPVRASQRLQTLPDGSL 4139 Query: 258 RLDNVILADEGEYSCEAENSVGAVS 282 L+ V D G Y C A N +G+ + Sbjct: 4140 WLERVEARDAGPYECVAHNLLGSAT 4164 Score = 124 bits (300), Expect = 1e-26 Identities = 123/477 (25%), Positives = 191/477 (40%), Gaps = 37/477 (7%) Query: 6 VTSGEAPYI--IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63 +T + PYI +QP ++ + P L C A G+P+P I W+K G + Sbjct: 3349 LTVMDPPYIEDSDQPEELLLTPGTPLELLCDARGTPTPNITWHKDGRALSWPEDGQ---- 3404 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123 G LR +V SDAG+Y C A + G A P Sbjct: 3405 GARRVLRVEGVQV-SDAGLYTCLAHSPAGEVEKSFRIRVQAPPNVIGSHGPRFVVGLAPG 3463 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183 +VLEC P P + W + G L D ++ +G L +Q D+G Y C A Sbjct: 3464 QLVLEC-SVEADPAPEIEWHREGVLLQADAHTQFP-EEGRFLQLQALSTADSGDYSCTAH 3521 Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA---- 239 NAAG+ +L H++ + P V A + C+ G P P V W + Sbjct: 3522 NAAGS-----TSLAFHVE---VHRPPTVNASVNQTTLLPCQADGVPQPLVSWLKDGVPLD 3573 Query: 240 -GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298 G L R + L +G LR+ V+ D G Y C A N G+ L V++PP+I Sbjct: 3574 PGSTRWVLAR-EGLREG-LRIQPVLAEDAGHYLCLASNPAGSDRQGRDLQVFEPPAIAPG 3631 Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358 P+++ + + A C A+G P+P + W +G + + + Y L + Sbjct: 3632 PSNLTLTAYTPASLPCEASGSPKPLVAWWKDGQKLDF--RLQQGAYRLLP----SNALLL 3685 Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418 + DS C N G + +TV PP I + ++ T I + V Sbjct: 3686 EEPSPQDSA-LFECVVSNGVGEARKLYWVTV-----HVPPAIADDQTDFTATIMAPVVLT 3739 Query: 419 CTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 C + P P+++W G L ++ + V+ G L + +G YTC A + G Sbjct: 3740 CHSTGVPAPVVSWSKAGTRLGVRGNGYRVSPSGALEIGQALPIHTGRYTCAARNAAG 3796 Score = 122 bits (293), Expect = 8e-26 Identities = 133/497 (26%), Positives = 201/497 (40%), Gaps = 47/497 (9%) Query: 30 TLNCRAGGSPSPAIRWYKGGVLV----VSDTHR-SILPAGGLFFLRATHGRVHSDAGVYW 84 TL C + P P I WYK G + V+ R IL G L ++ T SD+G Y Sbjct: 2537 TLECESWAVPPPTISWYKDGQNLPEKPVTPNQRVRILGEGRLLQIQPTQV---SDSGRYL 2593 Query: 85 CEATNSYGTA-RSRNATLH---VAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSPEPN 139 C ATN G + N + EE R E ++ + + L C P Sbjct: 2594 CVATNVAGEDDQDFNVLIQDFETPFWGEEARGGVTEYREIVENNPAYLYC-DTNAVPAAE 2652 Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199 + W + + L + D L G L I R DAGRY C A N G E + + Sbjct: 2653 LTWYRGDRPLSIE-DGVSVLQGGRVLQIPLVRAEDAGRYSCKASNEVG--EDWLHYELLV 2709 Query: 200 IKPYLITGP-----EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254 + P +I G E+V S+V+ C V G+P P + W ++ G P R++VL++ Sbjct: 2710 LTPPVILGETEELVEEVTVNANSTVSLHCPVLGNPAPTISWLQN-GLPFSPSPRLQVLEN 2768 Query: 255 GS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313 G L++ +AD Y C AEN G+ L V P +N P + + Sbjct: 2769 GRILQVSTAEVADAASYMCVAENPAGSTEKLFTLRVQGEPGLN--PEQITATLNSSVSLP 2826 Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373 C P P + W +G T+ + + + + G L + DS +C Sbjct: 2827 CDVRAHPSPEVTWYKDG-WTL---SLGEEIF----LLPGTHTLQLTRVQLLDS-GMYICE 2877 Query: 374 AVNYAGSSFVRGKLTVTSDD--DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431 A+N AG +L+V + RP ++ ++ AV C PEP +AW Sbjct: 2878 ALNAAGRDHKLVQLSVLAPGAPSRPQDVVLVSAGDK-------AVLSCETDAFPEPTVAW 2930 Query: 432 YFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490 +G+ L+ R G L ++D SD G Y+C S+ G+ + + +L V P P Sbjct: 2931 QKDGQPLVLPERIQALLGGQRLEIQDAQVSDKGLYSCRVSNAAGEAMRAFSLTVQVP--P 2988 Query: 491 NIHFFRAADVSSLPGPP 507 VS + G P Sbjct: 2989 TFENPETEMVSRVAGSP 3005 Score = 120 bits (288), Expect = 3e-25 Identities = 136/481 (28%), Positives = 210/481 (43%), Gaps = 55/481 (11%) Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75 E P V +P TL C A G P P + WY G+ VV D + + L AGG + G Sbjct: 1426 EGPRVVKAVAGRPLTLECVARGYPPPTVSWYHEGLPVV-DRNGTWLGAGGGVLSLESLGE 1484 Query: 76 VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDTVVLECLPPRG 134 + G+Y C A++ G A + ++ V V + E + + G ++ L C G Sbjct: 1485 --ASGGLYSCVASSPAGEA-VLHYSVEVQVAPQLLVAEGLGQVTTLVGQSLYLPCYAS-G 1540 Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193 SP P + W +NG + +H+ +G L I AG + C A N AGT +A Sbjct: 1541 SPVPTIQWLQNGHPA--EELPGVHVTSEGTTLHIDHVELGHAGLFACQATNEAGT-AAAE 1597 Query: 194 ATLKIHIKP-YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL 252 L +H P +I G E++ A VT +C G P P + W + G Sbjct: 1598 VELSVHELPSVVIVGGENITAPFLQPVTLRCAGTGVPTPSLRWWKD--------GVALAA 1649 Query: 253 DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN---VESGNV 309 GSL+++ V L DEG Y+C A N G L V PP N+ P VN +E+ +V Sbjct: 1650 SGGSLQIEKVDLKDEGTYTCVATNLAGESRKEVILRVLVPP--NIEPGLVNKAVLENASV 1707 Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369 C A+G P P W + G+ D+ AV+ GV + + Sbjct: 1708 T-LECLASGVPPPGKVWEL---------GLGNDE---PAVW-GVLYSLL--------KIC 1745 Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI- 428 +V + G R LTV + P + PS ++P ++ A+F C+ + + Sbjct: 1746 LVGGLLAGVGCEGARLALTVLA-----PGCSSLCPSLPSIPSQTTAIF-CSHPSSFQAFS 1799 Query: 429 -IAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486 I+W+ + + R V+ DG L+++ SD+G+Y CVAS+ G +L V++ Sbjct: 1800 NISWFKGRQPISAWDRAMVSTDGRVLLIEQAQLSDAGSYRCVASNVVGSTELQYSLRVNA 1859 Query: 487 P 487 P Sbjct: 1860 P 1860 Score = 118 bits (285), Expect = 7e-25 Identities = 125/488 (25%), Positives = 191/488 (39%), Gaps = 33/488 (6%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG---GLFFLRATHGRV 76 +VT H P +L C A G P P IRW++G VS + L AG + L+ T + Sbjct: 2238 NVTATLHSPLSLFCEATGIPPPGIRWFRGEE-PVSPGENTYLLAGKKISGWMLKLTRAQ- 2295 Query: 77 HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136 D G+Y C A+N G AR V VL R P G P Sbjct: 2296 EQDRGLYSCLASNEAGEAR---RDFSVEVLGTSPRGSHGRPPILPSSLRASGSGPSTGHP 2352 Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196 +P V W K+GQ L GD+ DG L + A + AG Y C+A NA G + L Sbjct: 2353 QPKVTWFKDGQPLA-SGDAHHVSPDGALLWVLHANLSSAGHYACVAANAIGEKTKHF-QL 2410 Query: 197 KIHIKPYLITGPED-----VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251 + + P ++ ED V + ++ C P P + W + G L +++ Sbjct: 2411 SVLVVPTILGVTEDSMDEEVTVTINNPISLICETRAFPTPTITWMKD-GVPFEALNNIQL 2469 Query: 252 L-DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN-------LSPNSVN 303 L L++ N D G+Y+C N +G + ++ V PPSI+ +S V Sbjct: 2470 LPGTHGLQILNAQKEDAGQYTCVVTNELGEAMKNYHVEVLIPPSISKDDLFGEVSMKEVK 2529 Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363 + + C + P PT+ W +G P + +L I T Sbjct: 2530 TKVNSTLTLECESWAVPPPTISWYKDGQN---LPEKPVTPNQRVRILGEGRLLQIQPTQV 2586 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP--PPIITNGPSN-QTLPIKSMAVFPCT 420 +DS +C A N AG + + D + P G + + + + A C Sbjct: 2587 SDS-GRYLCVATNVAGEDDQDFNVLI-QDFETPFWGEEARGGVTEYREIVENNPAYLYCD 2644 Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS-DSGTYTCVASSRHGKYVWS 479 P + WY L +V G ++ L ++ D+G Y+C AS+ G+ Sbjct: 2645 TNAVPAAELTWYRGDRPLSIEDGVSVLQGGRVLQIPLVRAEDAGRYSCKASNEVGEDWLH 2704 Query: 480 GALLVDSP 487 LLV +P Sbjct: 2705 YELLVLTP 2712 Score = 112 bits (269), Expect = 6e-23 Identities = 98/367 (26%), Positives = 150/367 (40%), Gaps = 22/367 (5%) Query: 116 SKQSAQGDTVVLECLPPRGSPE-PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTD 174 S S T + C P N+ W K G+ + D M DG L+I+ A+ +D Sbjct: 1776 SLPSIPSQTTAIFCSHPSSFQAFSNISWFK-GRQPISAWDRAMVSTDGRVLLIEQAQLSD 1834 Query: 175 AGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL 234 AG Y+C+A N G+ E +L+++ P ++ ++V SV +CR P P + Sbjct: 1835 AGSYRCVASNVVGSTELQY-SLRVNAPPSILGEEQNVSVVANESVALECRSHAVPPPVLS 1893 Query: 235 WRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294 WR+ G D L +D + D G Y+CEA N VG L V+ PP Sbjct: 1894 WRKDGRPLEPRPGVYLSADKALLEVDRAEVGDTGRYTCEALNQVGRSEKHYNLNVWVPPV 1953 Query: 295 I-NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353 + P ++ V G+ AR +C G P P + W +G PG + + A V Sbjct: 1954 FPSREPRTLTVTEGHPARLSCDCRGVPFPKISWKKDGQP---LPG----EGVSLAQVSAV 2006 Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413 L + T C N AG+S +L V PP I GP + Sbjct: 2007 GRLLYLGRAQPAQEGTYTCECSNVAGNSSQDQQLVVYV----PPRIA--GPLEPYADVSV 2060 Query: 414 M----AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCV 468 + A C A P P + W +G + + N G +L ++ + +G Y+CV Sbjct: 2061 VQDEEASLECNATGKPAPRVTWERDGWPVGPESGLRLQNHGQSLHVERAQPAHAGRYSCV 2120 Query: 469 ASSRHGK 475 A + G+ Sbjct: 2121 AENEAGR 2127 Score = 99 bits (238), Expect = 4e-19 Identities = 86/309 (27%), Positives = 127/309 (41%), Gaps = 20/309 (6%) Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVG 226 I A + + G Y+C A + AGT + + P L+ P +V G + C V Sbjct: 454 IPRASKAEEGTYECTAVSRAGTGRAKTQIVVTGPPPQLVPVP-NVTVSPGETAILSCLVL 512 Query: 227 GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY 286 + ++ W R + GRV L D SL + N +D G Y C A NS G AS + Sbjct: 513 SEAPYNLTWVRDWRVLSASTGRVTQLADLSLEVRNTTPSDGGRYQCMASNSNGVTRASVW 572 Query: 287 LTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHA 346 L V + P +++ S G R C+A+G P P + WS EG R + R Sbjct: 573 LLVREAPQVSIHTRSQRFSQGMEVRVRCSASGYPAPHISWSREG-RALQEDSRVRVDAQG 631 Query: 347 TAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN 406 T + GV + + C A N G R + TVT PP + + + Sbjct: 632 TLIIQGVA---------PEDAGSYSCQAANEIG----RDEETVTLYYTDPPSV--SAVNG 676 Query: 407 QTLPIK-SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465 L K AV C A P P + WY +I +++ G L + + + D+G Y Sbjct: 677 VVLAAKGEEAVLECEATGVPPPRVIWYRGDLEMILAPEDSIS--GMLRIPVVRERDAGVY 734 Query: 466 TCVASSRHG 474 TC A + G Sbjct: 735 TCRAVNELG 743 Score = 97.5 bits (232), Expect = 2e-18 Identities = 82/284 (28%), Positives = 119/284 (41%), Gaps = 14/284 (4%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I+ + +V+V ++ L CR+ P P + W K G + + + + L Sbjct: 1861 PSILGEEQNVSVVANESVALECRSHAVPPPVLSWRKDGRPL--EPRPGVYLSADKALLEV 1918 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131 V D G Y CEA N G + ++ L+V V EP + +G L C Sbjct: 1919 DRAEV-GDTGRYTCEALNQVGRS-EKHYNLNVWVPPVFPSREPRTLTVTEGHPARLSC-D 1975 Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRE 190 RG P P + WKK+GQ L +G S + G L+ + A+ G Y C N AG Sbjct: 1976 CRGVPFPKISWKKDGQPLPGEGVSLAQVSAVGRLLYLGRAQPAQEGTYTCECSNVAG-NS 2034 Query: 191 SAIATLKIHIKPYLITGP----EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 S L +++ P I GP DV + +C G P P V W R G P Sbjct: 2035 SQDQQLVVYVPP-RIAGPLEPYADVSVVQDEEASLECNATGKPAPRVTWERD-GWPVGPE 2092 Query: 247 GRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 +++ + G SL ++ A G YSC AEN G L+V Sbjct: 2093 SGLRLQNHGQSLHVERAQPAHAGRYSCVAENEAGRAERRFSLSV 2136 Score = 93.1 bits (221), Expect = 4e-17 Identities = 86/299 (28%), Positives = 123/299 (41%), Gaps = 24/299 (8%) Query: 43 IRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTAR---SRNA 99 I W+KG +S R+++ G L SDAG Y C A+N G+ S Sbjct: 1801 ISWFKGRQ-PISAWDRAMVSTDGRVLL--IEQAQLSDAGSYRCVASNVVGSTELQYSLRV 1857 Query: 100 TLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL 159 ++L EE ++ ++V LEC P P + W+K+G+ L + ++L Sbjct: 1858 NAPPSILGEE-----QNVSVVANESVALEC-RSHAVPPPVLSWRKDGRPL--EPRPGVYL 1909 Query: 160 -VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGS 217 D L + A D GRY C A N G E L + + P + P + G Sbjct: 1910 SADKALLEVDRAEVGDTGRYTCEALNQVGRSEKHY-NLNVWVPPVFPSREPRTLTVTEGH 1968 Query: 218 SVTFQCRVGGDPLPDVLWRRSA---GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEA 274 C G P P + W++ G + L +V + L L A EG Y+CE Sbjct: 1969 PARLSCDCRGVPFPKISWKKDGQPLPGEGVSLAQVSAV-GRLLYLGRAQPAQEGTYTCEC 2027 Query: 275 ENSVGAVSASGYLTVYDPPSI--NLSPNS-VNVESGNVARFTCTATGRPEPTMFWSVEG 330 N G S L VY PP I L P + V+V A C ATG+P P + W +G Sbjct: 2028 SNVAGNSSQDQQLVVYVPPRIAGPLEPYADVSVVQDEEASLECNATGKPAPRVTWERDG 2086 Score = 88.6 bits (210), Expect = 9e-16 Identities = 118/476 (24%), Positives = 190/476 (39%), Gaps = 47/476 (9%) Query: 17 QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD--THRSILPAGGLFFLRATHG 74 +P +TV PA L+C G P P I W K G + + + + G L +L G Sbjct: 1958 EPRTLTVTEGHPARLSCDCRGVPFPKISWKKDGQPLPGEGVSLAQVSAVGRLLYL----G 2013 Query: 75 RVH-SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS-AQGDTVVLECLPP 132 R + G Y CE +N G + + R LEP + S Q + LEC Sbjct: 2014 RAQPAQEGTYTCECSNVAGNSSQDQQLVVYVPPRIAGPLEPYADVSVVQDEEASLEC-NA 2072 Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192 G P P V W+++G + + R+ G +L ++ A+ AGRY C+A N AG E Sbjct: 2073 TGKPAPRVTWERDGWPVGPESGLRLQ-NHGQSLHVERAQPAHAGRYSCVAENEAGRAERR 2131 Query: 193 IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV---GGDPLPDVLWRRSAG--GGNMPLG 247 + + P G ++ Q S ++ + G PL + S N Sbjct: 2132 FSLSVLGEDPQPSGGGQEAARQPLSPCSWGHLLVLPGARPLANAALSGSCEHCSQNQDRL 2191 Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSP-NSVNV 304 ++ ++ S L++ + G E + YL PP + +L P +V Sbjct: 2192 QIALISLPSPHLNSYCIPQGGGEEWEE-------TRREYLV---PPELIGDLGPLTNVTA 2241 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 + C ATG P P + W G + PG + Y +L + + Sbjct: 2242 TLHSPLSLFCEATGIPPPGIRW-FRGEEP-VSPG--ENTYLLAGKKISGWMLKLTRAQEQ 2297 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR----PPPIITNGPSNQTLPIKSMAVFPCT 420 D R C A N AG + + V R PPI+ PS+ +++ P T Sbjct: 2298 D-RGLYSCLASNEAGEARRDFSVEVLGTSPRGSHGRPPIL---PSS----LRASGSGPST 2349 Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHGK 475 P+P + W+ +G+ L +V+ DG L+ + + S +G Y CVA++ G+ Sbjct: 2350 G--HPQPKVTWFKDGQPLASGDAHHVSPDGALLWVLHANLSSAGHYACVAANAIGE 2403 Score = 62.1 bits (144), Expect = 9e-08 Identities = 67/246 (27%), Positives = 94/246 (38%), Gaps = 21/246 (8%) Query: 248 RVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306 R V DG L ++ L+D G Y C A N VG+ L V PPSI +V+V + Sbjct: 1815 RAMVSTDGRVLLIEQAQLSDAGSYRCVASNVVGSTELQYSLRVNAPPSILGEEQNVSVVA 1874 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPG--MSRDKYHATAVFDGVTVLTINDTDKN 364 C + P P + W +G PG +S DK +L ++ + Sbjct: 1875 NESVALECRSHAVPPPVLSWRKDGRPLEPRPGVYLSADK----------ALLEVDRAEVG 1924 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424 D+ C A+N G S L V PP + P T+ A C Sbjct: 1925 DT-GRYTCEALNQVGRSEKHYNLNVWV----PPVFPSREPRTLTVTEGHPARLSCDCRGV 1979 Query: 425 PEPIIAWYFEGEALIQN--HRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHGKYVWSGA 481 P P I+W +G+ L V+ G L+ L + GTYTC S+ G Sbjct: 1980 PFPKISWKKDGQPLPGEGVSLAQVSAVGRLLYLGRAQPAQEGTYTCECSNVAGNSSQDQQ 2039 Query: 482 LLVDSP 487 L+V P Sbjct: 2040 LVVYVP 2045 >UniRef50_Q92859 Cluster: Neogenin precursor; n=34; Euteleostomi|Rep: Neogenin precursor - Homo sapiens (Human) Length = 1461 Score = 168 bits (409), Expect = 7e-40 Identities = 186/730 (25%), Positives = 288/730 (39%), Gaps = 84/730 (11%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169 F +EP S +G +V+L C P P + WKK+G L D R L+ G+L I + Sbjct: 55 FLVEPVDTLSVRGSSVILNC-SAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISN 113 Query: 170 A-----RQTDAGRYQCIAR-NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223 + D G YQC+A + GT S A L + P + PE G++ C Sbjct: 114 VVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYAGNNAILNC 173 Query: 224 RVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA 280 V D +P V W ++ PL RV L G L + N D G Y C E+ G Sbjct: 174 EVNADLVPFVRWEQN----RQPLLLDDRVIKLPSGMLVISNATEGDGGLYRCVVESG-GP 228 Query: 281 VSASGYLTVY---DPPSIN-----LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332 S + + DP I+ P+ + G C A+G P PT+ W Sbjct: 229 PKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEE- 287 Query: 333 TIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD 392 + + + G + L I+D ++D+ T C A N + + +LTV + Sbjct: 288 -----ALDTESSERLVLLAGGS-LEISDVTEDDA-GTYFCIADNGNETIEAQAELTVQAQ 340 Query: 393 DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTL 452 P P+N VF C P P + W G+ +I + + + L Sbjct: 341 -----PEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNL 395 Query: 453 VLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPIT 512 + L KSD G Y C+A + G +GA L+ P A LP P + Sbjct: 396 QVLGLVKSDEGFYQCIAENDVGN-AQAGAQLIILEHAP-------ATTGPLPSAPRDVVA 447 Query: 513 HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHY 572 V+ + L+W L Y V +++E ++ S + Sbjct: 448 SLVSTRFIKLTWRTPASDPHGDNLTYSV-FYTKEGIARERVENTS--------HPGEMQV 498 Query: 573 VVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILT 632 +++L+P Y+F V +N HG SG S S + V G + R + Sbjct: 499 TIQNLMPATVYIFRVMAQNKHG-SGES--SAPLRVETQPEVQLPGP----APNLRAYAAS 551 Query: 633 DHIVELIEATPIDSKTIKLMWEILNF--YYLEGLFIYFRPLDNITIEYEMKTILHSNDVS 690 + + TP+ EI N+ YY+E + D E ++ HS ++ Sbjct: 552 PTSITVTWETPVSGN-----GEIQNYKLYYME------KGTDK---EQDVDVSSHSYTIN 597 Query: 691 GFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHL 750 G L+KYT+Y F ++ + K G + +TL DVP P N+ + + N+ ++ + Sbjct: 598 G-----LKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMI 652 Query: 751 KWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQI 810 W PP QNG ITGY + + KS V S ++ L G Y+ ++ Sbjct: 653 HWQPPAPATQNGQITGYKIRYR---KASRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRV 709 Query: 811 AAETIIGLGP 820 AA TI G GP Sbjct: 710 AALTINGTGP 719 Score = 162 bits (393), Expect = 6e-38 Identities = 144/569 (25%), Positives = 232/569 (40%), Gaps = 45/569 (7%) Query: 13 YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGLFFLR 70 Y + +P+D R LNC A PSP I W K G + VSD R +LP G LF Sbjct: 54 YFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISN 113 Query: 71 ATHGRVHS-DAGVYWCEAT-NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128 H + + D G Y C AT S GT SR A L VA L F +PE G+ +L Sbjct: 114 VVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGL-PRFTSQPEPSSVYAGNNAILN 172 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188 C P V W++N Q LL D R+ + G LVI +A + D G Y+C+ + Sbjct: 173 C-EVNADLVPFVRWEQNRQPLLLD--DRVIKLPSGMLVISNATEGDGGLYRCVVESGGPP 229 Query: 189 RESAIATLKIHIKPYLITG------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242 + S LK+ P +I+ P +V G V C G P P + W ++ Sbjct: 230 KYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEAL 289 Query: 243 NMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301 + R+ +L GSL + +V D G Y C A+N + A LTV P P + Sbjct: 290 DTESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTN 349 Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361 + F C TG+P PT+ W G+ ++ P Y + VL + + Sbjct: 350 IYAHESMDIVFECEVTGKPTPTVKWVKNGD--MVIP----SDYFKIVKEHNLQVLGLVKS 403 Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT- 420 D+ + C A N G++ +L + + + P + + S T Sbjct: 404 DEGFYQ----CIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTW 459 Query: 421 AICTPEP-----IIAWYFEGEALIQNHRRNVTNDGTL--VLKDLDKSDSGTYTCVASSRH 473 +P + ++ E + + N ++ G + +++L + + +A ++H Sbjct: 460 RTPASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKH 519 Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSS 533 G S L V++ P + LPGP + + TS+T++W + G+ Sbjct: 520 GSGESSAPLRVET--QPEV---------QLPGPAPNLRAYAASPTSITVTW-ETPVSGNG 567 Query: 534 SILGYQVEVFSRETLSGNNTPRNSRGWVV 562 I Y++ + T + +S + + Sbjct: 568 EIQNYKLYYMEKGTDKEQDVDVSSHSYTI 596 Score = 135 bits (326), Expect = 8e-30 Identities = 190/826 (23%), Positives = 326/826 (39%), Gaps = 74/826 (8%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P QP +V A LNC P +RW + ++ D LP+G L A Sbjct: 152 PRFTSQPEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPLLLDDRVIKLPSGMLVISNA 211 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHV----AVLRE-EFRLEPESKQSAQGDTVV 126 T G D G+Y C + S L V V+ + F +P G VV Sbjct: 212 TEG----DGGLYRCVVESGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVV 267 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186 L C+ G P P + W KN + L + R+ L+ GG+L I D + DAG Y CIA N Sbjct: 268 LPCV-ASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGN 326 Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 T E A A L + +P + P ++ A + F+C V G P P V W ++ G +P Sbjct: 327 ETIE-AQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKN-GDMVIPS 384 Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PPSINLSPNSV-N 303 K++ + +L++ ++ +DEG Y C AEN VG A L + + P + P++ + Sbjct: 385 DYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRD 444 Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIF--PGMSRDKYHATAVFDGVTVLTINDT 361 V + V+ T R + ++ + G++R++ T+ G +TI Sbjct: 445 VVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARERVENTS-HPGEMQVTI--- 500 Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421 +N T+ V A + G+ + + P + GP+ +++ A P + Sbjct: 501 -QNLMPATVYIFRV-MAQNKHGSGESSAPLRVETQPEVQLPGPAPN---LRAYAASPTSI 555 Query: 422 ICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481 T E ++ G IQN++ GT +D+D S S +YT ++ +Y S Sbjct: 556 TVTWETPVS----GNGEIQNYKLYYMEKGTDKEQDVDVS-SHSYTINGLKKYTEY--SFR 608 Query: 482 LLVDSPINPNIHFFRAA--DVSSLPGPPTKPITHNVTDT-SVTLSWS-QNNKIGSSSILG 537 ++ + P + A +S +P + ++ V ++ S+ + W + I G Sbjct: 609 VVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITG 668 Query: 538 YQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSG 597 Y++ + + + + T G Q +++ L G Y F V ++G Sbjct: 669 YKIR-YRKASRKSDVTETLVSG--------TQLSQLIEGLDRGTEYNFRVAALT---ING 716 Query: 598 PSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILN 657 P +D ++ + L E + L IV + TP +++ I + Sbjct: 717 TGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIV--VSWTPPENQNIVVRG---- 770 Query: 658 FYYLEGLFIYFRPLDNITIEYEMKTILHSN-DVSGFEITSLRKYTKYEFFLIPFYKKFEG 716 Y G I I ++Y+ + N D S + +L+ + IP Y+ Sbjct: 771 --YAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEG-IPLYESAVT 827 Query: 717 KPS-----------NSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIIT 765 +P N+ D P PP+ ++ IL+ T+ + W+ L I Sbjct: 828 RPHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITD 887 Query: 766 GYNVVVNW-LDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQI 810 V W ++PAN N T S ++T L Y + Sbjct: 888 SRYYTVRWKTNIPANTKYKNANAT---TLSYLVTGLKPNTLYEFSV 930 Score = 79.0 bits (186), Expect = 7e-13 Identities = 81/301 (26%), Positives = 127/301 (42%), Gaps = 20/301 (6%) Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241 A + +S A+++ Y + P D ++ GSSV C +P P + W++ Sbjct: 33 AARSGSAPQSPGASIRTFTPFYFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTF 92 Query: 242 GNMPL-GRVKVLDDGSLRLDNVILA-----DEGEYSCEAE-NSVGA-VSASGYLTVYDPP 293 N+ R ++L DGSL + NV+ + DEG Y C A S+G +S + L V P Sbjct: 93 LNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLP 152 Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353 P +V +GN A C P + W E NR P + D+ + G+ Sbjct: 153 RFTSQPEPSSVYAGNNAILNCEVNADLVPFVRW--EQNRQ---PLLLDDR--VIKLPSGM 205 Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIK 412 V++ N T+ + V + S +L V D + ++ PS I Sbjct: 206 LVIS-NATEGDGGLYRCVVESGGPPKYS-DEVELKVLPDPEVISDLVFLKQPSPLVRVIG 263 Query: 413 SMAVFPCTAICTPEPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470 V PC A P P I W EAL + R + G+L + D+ + D+GTY C+A Sbjct: 264 QDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIAD 323 Query: 471 S 471 + Sbjct: 324 N 324 Score = 46.0 bits (104), Expect = 0.006 Identities = 38/136 (27%), Positives = 57/136 (41%), Gaps = 5/136 (3%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILN--TTTVHLK 751 +T L+ T YEF ++ + S + T + VP PP ++ + T+ + Sbjct: 917 VTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVPTSPPKDVTVVSKEGKPKTIIVN 976 Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811 W PP NG ITGY ++ DV A I V + + LT Y +I Sbjct: 977 WQPPSEA--NGKITGY-IIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQ 1033 Query: 812 AETIIGLGPFSQKVYF 827 A G+GP S+ V F Sbjct: 1034 ARNSKGMGPMSEAVQF 1049 >UniRef50_O94779 Cluster: Contactin-5 precursor; n=52; Euteleostomi|Rep: Contactin-5 precursor - Homo sapiens (Human) Length = 1100 Score = 167 bits (405), Expect = 2e-39 Identities = 136/491 (27%), Positives = 206/491 (41%), Gaps = 33/491 (6%) Query: 12 PYIIEQPLDV---TVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68 P +++P D+ T + + LNC G+P P+ RW + G + ++ G F Sbjct: 99 PVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFI 158 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128 + ++ D+G Y C ATN+ G+ SR ATL A L + +G VVL Sbjct: 159 I--SNPSEAKDSGHYQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLM 216 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAG 187 C PP SPE W N DSR + + GNL I + +D G Y C+ +N Sbjct: 217 CSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTVT 276 Query: 188 TRESAIATLKIHIKPYLITG----------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 + ++ + G P V A G++V +C G+P+P + W + Sbjct: 277 NARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMK 336 Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297 G +P L + NV L D G Y C AENS G S G L VY P Sbjct: 337 V--NGYIPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVE 394 Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 N ++SG+ R+ C ATG+P PT W G + SR + +G VL Sbjct: 395 KLNDTQLDSGSPLRWECKATGKPRPTYRWLKNG---VPLSPQSR-----VEMVNG--VLM 444 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM-AV 416 I++ +++D+ C A N G+ + +L + + P N + K V Sbjct: 445 IHNVNQSDA-GMYQCLAENKYGAIYASAELKILAS---APTFALNQLKKTIIVTKDQEVV 500 Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476 C +P+P I+W A+ +N R + DG+L + + KSD G Y C + G Sbjct: 501 IECKPQGSPKPTISWKKGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSA 560 Query: 477 VWSGALLVDSP 487 +L V P Sbjct: 561 EIIASLSVKEP 571 Score = 119 bits (287), Expect = 4e-25 Identities = 98/336 (29%), Positives = 143/336 (42%), Gaps = 19/336 (5%) Query: 1 MSDDYVTSGEAPYI-IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRS 59 + +D V P I + P VT A+ + C A G+P P I W K + S Sbjct: 289 LRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLR 348 Query: 60 ILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS 119 A L + ++ DAG+Y C A NS G S L V + Q Sbjct: 349 KSQA----VLEIPNVQL-DDAGIYECRAENSRGK-NSFRGQLQVYTYPHWVE-KLNDTQL 401 Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179 G + EC G P P W KNG L SR+ +V+G L+I + Q+DAG YQ Sbjct: 402 DSGSPLRWEC-KATGKPRPTYRWLKNGVPL--SPQSRVEMVNGV-LMIHNVNQSDAGMYQ 457 Query: 180 CIARNAAGTRESAIATLKIHIK-PYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 C+A N G ++ A LKI P + ++ V +C+ G P P + W+ Sbjct: 458 CLAENKYGAIYAS-AELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWK 516 Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296 + R+ +L DGSLR+ N +DEG+Y C EN G+ L+V +P I Sbjct: 517 KGDRAVRENK-RIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIE 575 Query: 297 LSPNSVNVESGNVARFTCTA--TGRPEPTMFWSVEG 330 L+P + G C A + T +W+++G Sbjct: 576 LTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKG 611 Score = 107 bits (258), Expect = 1e-21 Identities = 91/320 (28%), Positives = 135/320 (42%), Gaps = 27/320 (8%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P+ +E+ D + P C+A G P P RW K GV +S R + G L Sbjct: 390 PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGV-PLSPQSRVEMVNGVLMI--- 445 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS--AQGDTVVLEC 129 H SDAG+Y C A N YG + +A L + F L K + VV+EC Sbjct: 446 -HNVNQSDAGMYQCLAENKYGAIYA-SAELKILASAPTFALNQLKKTIIVTKDQEVVIEC 503 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189 P+GSP+P + WKK + + + R+ ++ G+L I +A ++D G+Y C N G+ Sbjct: 504 -KPQGSPKPTISWKKGDRAVR--ENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSA 560 Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL--WRRSAG------- 240 E IA+L + + P+ G S+ C+ D DV W Sbjct: 561 E-IIASLSVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEE 619 Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300 GG+ R + L + N++L G Y C + + +VS L V PP P Sbjct: 620 GGHFESIRAQA-SSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPG---PPG 675 Query: 301 SVNVESGNVARFTCTATGRP 320 V VE + T T + P Sbjct: 676 IVIVE--EITESTATLSWSP 693 >UniRef50_UPI0000F2B6E2 Cluster: PREDICTED: hypothetical protein; n=1; Monodelphis domestica|Rep: PREDICTED: hypothetical protein - Monodelphis domestica Length = 3881 Score = 166 bits (404), Expect = 3e-39 Identities = 143/475 (30%), Positives = 198/475 (41%), Gaps = 34/475 (7%) Query: 11 APYIIEQ--PLDVTVARHQPATLNCRAGGSPSPAIRWYKGG--VLVVSDTHRSILPAGGL 66 AP I+ P + + Q L C A G P P I W K G + V + H G Sbjct: 2854 APRILSSGVPQEHNILEEQEVRLECEAEGQPQPDISWLKDGRPLGVHTAPHLRFYTDGSS 2913 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGT-ARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 L+ G SD+G Y C A NS G + ++ V E E+ S QG+ V Sbjct: 2914 LVLK---GLKSSDSGAYTCLAQNSVGEDTKLHTVSVLVPPTIERGANGSENLISVQGELV 2970 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 + C P RGSP + W K+G + + +H G L I + DAG + C+A + Sbjct: 2971 TMAC-PARGSPPIQINWLKDGLPMPLSQRTHLHS-SGRTLRISQVQVADAGTFTCVASSP 3028 Query: 186 AGTRESAIATLKIHIKPYLITGP-EDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 AG E + L+IH+ P L +D +A GS VT C G PLP V W + G + Sbjct: 3029 AGVAERTFS-LQIHVPPVLEPSETKDAMAVVRGSDVTLPCEARGSPLPAVSWLKD--GAS 3085 Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS--PNS 301 + L R+ + SL+L+ V D G YSC A N G + L V +PP I S Sbjct: 3086 LMLQRLGLGSGSSLQLEAVQADDVGTYSCVAINEAGEATRHFQLAVMEPPHIEDSGQAEE 3145 Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361 + + G C A G P P + W +G +++D +GV V Sbjct: 3146 MLLLPGAPLELICNALGSPMPNITWQKDGQVLARLGSITKD--GRVLRVEGVQV------ 3197 Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI-KSMAVFPCT 420 D C A N AG + V + PP I+ + + + + V C Sbjct: 3198 ---DDAGLYTCLAENPAGEDGKNFLVRVQA----PPNIVGSRETRTVIGLADGQLVLECP 3250 Query: 421 AICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 P P I W+ EG L H + N L L+ LD SDSG Y CVAS+ G Sbjct: 3251 VEADPPPKIEWHREGVLLQADAHTLFLENGRFLQLQALDTSDSGDYNCVASNAAG 3305 Score = 165 bits (400), Expect = 9e-39 Identities = 136/481 (28%), Positives = 213/481 (44%), Gaps = 34/481 (7%) Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGLFFLRATH 73 ++P+ +T + TL+C A GSPSP I W K L+ ++D H S+LP+G L + Sbjct: 987 DRPVTITALAGKELTLHCEAEGSPSPLITWTKDSQLLSPITDRH-SLLPSGSLKLAETSV 1045 Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133 D G+Y C A+N GTA SR+ L V V + + P+ + G+++ L C+ Sbjct: 1046 ----EDNGLYTCIASNPAGTA-SRSYVLGVQV-PPQIQQGPQLLKVLAGESLDLTCVAT- 1098 Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193 G P+P + W K+G TL G + G++ ++ + +D+G Y C+A + AG + Sbjct: 1099 GDPKPQLRWSKDGITLPQKG----WVGPDGSVHLESVQVSDSGHYHCVASSEAGEDAREL 1154 Query: 194 ATLKIHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR-VKV 251 + + E ++ + G + + C V G P P V+WR+ + + V Sbjct: 1155 ELEVLEPPRWEAEDAEALLERVAGENASLPCPVTGTPTPRVIWRKDPAPELLSSQPGLSV 1214 Query: 252 LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE--SGNV 309 L+D SL + +V D G+Y C A N VG+VS L VY PP VNV + Sbjct: 1215 LNDSSLFIASVSSQDSGDYECRATNEVGSVSRKVKLVVYVPPHFRGEEQRVNVSTLASRP 1274 Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369 C +G P P + W +G +S D H DG L K+DS + Sbjct: 1275 LTLNCDVSGFPTPAITWYKDGR------PVSEDNRHYFP--DGAPSLHFPQVQKSDS-DL 1325 Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPI 428 C AVN AG + L V PP + G + + + + V C P P Sbjct: 1326 YTCQAVNPAGMAQKDFNLLVLI----PPSVRGAGTAQEVSRLAGLEVELECRTSGVPLPQ 1381 Query: 429 IAWYFEGEALIQN--HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486 + W +G+ + H + V + L + D+G Y CVA S G+ L + + Sbjct: 1382 VEWTKDGQPVAPGDPHIQLVEDGQVLKIPSSHLGDAGHYQCVAFSPAGQQAKDFQLSIQT 1441 Query: 487 P 487 P Sbjct: 1442 P 1442 Score = 164 bits (399), Expect = 1e-38 Identities = 135/461 (29%), Positives = 197/461 (42%), Gaps = 31/461 (6%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80 + V R TL C A GSP PA+ W K G ++ R L +G L A D Sbjct: 3055 MAVVRGSDVTLPCEARGSPLPAVSWLKDGASLM--LQRLGLGSGSSLQLEAVQA---DDV 3109 Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140 G Y C A N G A + E + E G + L C GSP PN+ Sbjct: 3110 GTYSCVAINEAGEATRHFQLAVMEPPHIEDSGQAEEMLLLPGAPLELIC-NALGSPMPNI 3168 Query: 141 YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200 W+K+GQ L G DG L ++ + DAG Y C+A N AG + +++ Sbjct: 3169 TWQKDGQVLARLGSITK---DGRVLRVEGVQVDDAGLYTCLAENPAG-EDGKNFLVRVQA 3224 Query: 201 KPYLITGPED--VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-L 257 P ++ E V+ + +C V DP P + W R G L++G L Sbjct: 3225 PPNIVGSRETRTVIGLADGQLVLECPVEADPPPKIEWHRE-GVLLQADAHTLFLENGRFL 3283 Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317 +L + +D G+Y+C A N+ G+ S + ++ P+I P+ VNV A C Sbjct: 3284 QLQALDTSDSGDYNCVASNAAGSTSLPFSVEIHMAPTIQPGPSVVNVSVNETALLPCKTR 3343 Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377 G P + W +G + PG R ++ + DG L I DS +C A N Sbjct: 3344 GLPVSLVSWRKDGIPLV--PGSPRLEF----LSDGS--LRIQPVYPQDS-GYYLCQASNS 3394 Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437 AGS +L V PP I GPSN TL + + A PC A +P+P + W G+ Sbjct: 3395 AGSDRQGRELRVFE-----PPTIAPGPSNLTLTVHTQATLPCEARGSPKPHVVWKKNGQT 3449 Query: 438 L-IQNHRR--NVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 L + H+ + +LVL D D D+ + C+ S+ G+ Sbjct: 3450 LSLDRHQEAYRLLPSSSLVLTDPDLQDTAQFECLVSNDAGE 3490 Score = 162 bits (394), Expect = 5e-38 Identities = 140/470 (29%), Positives = 211/470 (44%), Gaps = 30/470 (6%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 + P + P +VTV+ + A L+C+ + W + ++ + R + A Sbjct: 427 DPPPQLASPQNVTVSPGETALLSCQVLDKAPYNLTWVRDWRVLPASPGRVVQLAN---LS 483 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVVL 127 G + SD G Y C A+N+ G R+ L +RE + + S+ +QG + + Sbjct: 484 LEISGIIPSDGGKYQCLASNANGITRASVWLL----IREPPQISINTSSRHFSQGVELRI 539 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 C G P P++ W+ N QT+ DG R + D G L+IQ DAG Y C A N G Sbjct: 540 SCTAS-GYPPPHISWRHNDQTIGMDG--RFLVDDQGTLIIQSVTPEDAGNYSCQATNEVG 596 Query: 188 TRESAIATLKIHIKPYLITGPEDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 T E + TL + +P ++ VV A G +C+ G P P V+W R GG M L Sbjct: 597 TDEQTV-TL-FYTEPPSVSALRPVVLAPIGEEAVLECKASGVPPPRVIWYR--GGLEMIL 652 Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV-YDPPSINLSPNSVNVE 305 +V G+LR+ V D G Y C+A N +GA SA L V Y P + S N V VE Sbjct: 653 AP-EVAHTGTLRIQEVQERDAGNYICKAVNELGAASADIRLEVGYAPRLVESSRNMV-VE 710 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365 G A C A GRP P + W+ + + P + A + GV L N T ++ Sbjct: 711 MGRNAILACRAEGRPSPRITWARVDGKPV--PAHPVEGNRARQLEAGVLFLE-NVTPEDQ 767 Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC-T 424 + +C A N G + +LTV + PP I + S + A PC + Sbjct: 768 A--LYICEAHNTFGKAQAEVQLTVIGHE---PPQIASSASMVRVLEGQPASLPCVVLAGK 822 Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 P P W EG+ L + R ++ DG+ + + D+G Y+CV ++ G Sbjct: 823 PFPQRHWLKEGQPL-PSSRYSIRTDGSFHIDRALQEDAGRYSCVVTNTVG 871 Score = 161 bits (391), Expect = 1e-37 Identities = 150/501 (29%), Positives = 214/501 (42%), Gaps = 46/501 (9%) Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG--LFFLRATH 73 EQ ++V+ +P TLNC G P+PAI WYK G VS+ +R P G L F + Sbjct: 1262 EQRVNVSTLASRPLTLNCDVSGFPTPAITWYKDG-RPVSEDNRHYFPDGAPSLHFPQVQK 1320 Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133 SD+ +Y C+A N G A+ L + + G V LEC Sbjct: 1321 ----SDSDLYTCQAVNPAGMAQKDFNLLVLIPPSVRGAGTAQEVSRLAGLEVELECRTS- 1375 Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESA 192 G P P V W K+GQ + GD + LV+ G ++ I + DAG YQC+A + AG +++ Sbjct: 1376 GVPLPQVEWTKDGQPVA-PGDPHIQLVEDGQVLKIPSSHLGDAGHYQCVAFSPAG-QQAK 1433 Query: 193 IATLKIHIKPYLITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250 L I P + E +V V QC G P P + W + G RV Sbjct: 1434 DFQLSIQTPPTIWGSNETGEVAVMEDHVVRLQCDARGVPTPAITWLKD-GDPLHASPRVA 1492 Query: 251 VLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI---NLSPNSVNVES 306 G L+L +D G Y+C+A N+ G + L VY PP+I + P V + Sbjct: 1493 YAKGGRHLQLGRARGSDSGLYTCQASNAAGIAEKAVRLDVYVPPTIEGADGGPLVVKAVA 1552 Query: 307 GNVARFTCTATGRPEPTMFWS------VEGNRTIIFPGMSRDKY----HATAVFDGVTVL 356 G C+A+G P PT+ W E N T + G ++ F GV V Sbjct: 1553 GRPLALGCSASGHPPPTLTWHQDENPLTENNGTWLQEGGRVLRWLRNGRPAEEFAGVEVS 1612 Query: 357 TIN-----DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411 T D + D C A N AG++ ++ V ++P + G N T P Sbjct: 1613 TDGAMLRIDHVQPDHNGLFACQATNEAGTAGAEVEVLV---HEQPSVTVLEG-ENITAPF 1668 Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471 C A P P ++W+ G +L VT G+L ++ +D D G YTCVA++ Sbjct: 1669 LQPVTIQCVAAGMPVPNLSWWKNGVSL-------VTTGGSLQIEKVDLRDEGNYTCVATN 1721 Query: 472 RHGKYVWSGALLVDSPINPNI 492 G+ L V P PNI Sbjct: 1722 LAGEAKRDVVLKVLVP--PNI 1740 Score = 158 bits (383), Expect = 1e-36 Identities = 133/479 (27%), Positives = 195/479 (40%), Gaps = 36/479 (7%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLV----VSDTHRSILPA 63 G AP ++E ++ V + A L CRA G PSP I W + G V V L A Sbjct: 695 GYAPRLVESSRNMVVEMGRNAILACRAEGRPSPRITWARVDGKPVPAHPVEGNRARQLEA 754 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123 G LF T D +Y CEA N++G A++ + + + +G Sbjct: 755 GVLFLENVT----PEDQALYICEAHNTFGKAQAEVQLTVIGHEPPQIASSASMVRVLEGQ 810 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183 L C+ G P P +W K GQ L SR + G+ I A Q DAGRY C+ Sbjct: 811 PASLPCVVLAGKPFPQRHWLKEGQPL---PSSRYSIRTDGSFHIDRALQEDAGRYSCVVT 867 Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 N G++ I L + + P ++ V G ++ C G P P + WR+ + Sbjct: 868 NTVGSQRQDI-ELAVQVLPSILPTASHYVTNEGVPISLPCVSRGIPTPTITWRKETNALS 926 Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS----- 298 +VL +GSL L D G Y C A N++G S L+V P I ++ Sbjct: 927 PRSSHHQVLKEGSLYLPQPSAQDSGTYVCTATNALGISSQEIQLSVNTKPRIIMNESLDS 986 Query: 299 --PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356 P ++ +G C A G P P + W+ + ++ P R + + G L Sbjct: 987 DRPVTITALAGKELTLHCEAEGSPSPLITWTKDSQ--LLSPITDRH----SLLPSGSLKL 1040 Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416 + N I + A S+V G + PP I GP + Sbjct: 1041 AETSVEDNGLYTCIASNPAGTASRSYVLGV--------QVPPQIQQGPQLLKVLAGESLD 1092 Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 C A P+P + W +G L Q + V DG++ L+ + SDSG Y CVASS G+ Sbjct: 1093 LTCVATGDPKPQLRWSKDGITLPQ--KGWVGPDGSVHLESVQVSDSGHYHCVASSEAGE 1149 Score = 155 bits (376), Expect = 7e-36 Identities = 130/500 (26%), Positives = 221/500 (44%), Gaps = 38/500 (7%) Query: 5 YVTSGEAPYIIEQPLDVTVAR--HQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62 +V + P I E P T+++ P L C G P+P + W K + V S R ++ Sbjct: 2755 FVLIVQVPPIFENPEKETLSQVAGNPLVLVCDVAGVPAPTVTWLKDRMPVESSVERGVVS 2814 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122 GG L S G Y C A N AR + + R P+ + Sbjct: 2815 RGGRLQLSRLQ---PSQEGTYTCVAENPEAEARKDFVVMVLVAPRILSSGVPQEHNILEE 2871 Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181 V LEC G P+P++ W K+G+ L + DG +LV++ + +D+G Y C+ Sbjct: 2872 QEVRLEC-EAEGQPQPDISWLKDGRPLGVHTAPHLRFYTDGSSLVLKGLKSSDSGAYTCL 2930 Query: 182 ARNAAGTRESAIATLKIHIKPYL---ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238 A+N+ G ++ + T+ + + P + G E++++ G VT C G P + W + Sbjct: 2931 AQNSVG-EDTKLHTVSVLVPPTIERGANGSENLISVQGELVTMACPARGSPPIQINWLKD 2989 Query: 239 AGGGNMPLG-RVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296 G MPL R + G +LR+ V +AD G ++C A + G + L ++ PP + Sbjct: 2990 --GLPMPLSQRTHLHSSGRTLRISQVQVADAGTFTCVASSPAGVAERTFSLQIHVPPVLE 3047 Query: 297 LS--PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354 S +++ V G+ C A G P P + W +G ++ + G + Sbjct: 3048 PSETKDAMAVVRGSDVTLPCEARGSPLPAVSWLKDGASLML---------QRLGLGSGSS 3098 Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414 + + + D T C A+N AG + +L V PP I +G + + L + Sbjct: 3099 LQL--EAVQADDVGTYSCVAINEAGEATRHFQLAVM----EPPHIEDSGQAEEMLLLPGA 3152 Query: 415 AV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSR 472 + C A+ +P P I W +G+ L + ++T DG L ++ + D+G YTC+A + Sbjct: 3153 PLELICNALGSPMPNITWQKDGQVLAR--LGSITKDGRVLRVEGVQVDDAGLYTCLAENP 3210 Query: 473 HGKYVWSGALLVDSPINPNI 492 G+ + + V +P PNI Sbjct: 3211 AGEDGKNFLVRVQAP--PNI 3228 Score = 153 bits (371), Expect = 3e-35 Identities = 134/469 (28%), Positives = 202/469 (43%), Gaps = 25/469 (5%) Query: 10 EAPYIIE--QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67 E P+I + Q ++ + P L C A GSP P I W K G ++ SI G + Sbjct: 3133 EPPHIEDSGQAEEMLLLPGAPLELICNALGSPMPNITWQKDGQVLAR--LGSITKDGRV- 3189 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV-AVLREEFRLEPESKQSAQGDTVV 126 LR +V DAG+Y C A N G +N + V A E + +V Sbjct: 3190 -LRVEGVQV-DDAGLYTCLAENPAGED-GKNFLVRVQAPPNIVGSRETRTVIGLADGQLV 3246 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186 LEC P P P + W + G L D + + L +G L +Q +D+G Y C+A NAA Sbjct: 3247 LEC-PVEADPPPKIEWHREGVLLQADAHT-LFLENGRFLQLQALDTSDSGDYNCVASNAA 3304 Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 G+ S +++IH+ P + GP V + C+ G P+ V WR+ Sbjct: 3305 GST-SLPFSVEIHMAPTIQPGPSVVNVSVNETALLPCKTRGLPVSLVSWRKDGIPLVPGS 3363 Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306 R++ L DGSLR+ V D G Y C+A NS G+ L V++PP+I P+++ + Sbjct: 3364 PRLEFLSDGSLRIQPVYPQDSGYYLCQASNSAGSDRQGRELRVFEPPTIAPGPSNLTLTV 3423 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 A C A G P+P + W G +S D++ + L + D D D+ Sbjct: 3424 HTQATLPCEARGSPKPHVVWKKNGQT------LSLDRHQEAYRLLPSSSLVLTDPDLQDT 3477 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426 C N AG + R VT PP I + ++ T+ + V C P Sbjct: 3478 AQ-FECLVSNDAGET--RRLFWVTV---YVPPTIADDRTDFTVTKMAPVVLTCHTTGVPT 3531 Query: 427 PIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 P+++W G L + V+ G L ++ +G YTC A + G Sbjct: 3532 PVVSWSKGGAQLGKRGSGYRVSPTGALEIEQALPIHTGRYTCTARNAAG 3580 Score = 151 bits (365), Expect = 1e-34 Identities = 131/482 (27%), Positives = 202/482 (41%), Gaps = 49/482 (10%) Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR-- 75 PL V +P L C A G P P + W++ +++ + + L GG +GR Sbjct: 1545 PLVVKAVAGRPLALGCSASGHPPPTLTWHQDEN-PLTENNGTWLQEGGRVLRWLRNGRPA 1603 Query: 76 -------VHSDA-------------GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPE 115 V +D G++ C+ATN GTA + L V LE E Sbjct: 1604 EEFAGVEVSTDGAMLRIDHVQPDHNGLFACQATNEAGTAGAEVEVL-VHEQPSVTVLEGE 1662 Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175 + + V ++C+ G P PN+ W KNG +L+ GG+L I+ D Sbjct: 1663 NITAPFLQPVTIQCVAA-GMPVPNLSWWKNGVSLV---------TTGGSLQIEKVDLRDE 1712 Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235 G Y C+A N AG + + LK+ + P + G + +S + +C G P P + W Sbjct: 1713 GNYTCVATNLAGEAKRDVV-LKVLVPPNIEPGLVNKAVLENTSASLECLASGVPTPRISW 1771 Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295 R + G + D LR+ L+D G Y C A N G+ L + PP I Sbjct: 1772 YRGRQPISSKPGLMVSSDGRVLRIKRAQLSDAGSYRCVASNVAGSSELKFGLRINVPPRI 1831 Query: 296 NLSPNSVN-VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354 L+P+ V R C ATG P P + W +GN + G S +F G Sbjct: 1832 TLAPSLPGPVLLNEPVRLVCNATGAPTPMLMWLKDGN-PVSATGTS-----GLQIFPGGH 1885 Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414 VLT+ + D+ T C AVN G + VT PP I+ N ++ + Sbjct: 1886 VLTLAGSRATDA-GTYTCVAVNAVGED----RRDVTLQVHLPPSIL-GEEQNVSVVVNQS 1939 Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRH 473 C + P P+++W +G AL +++ DG L+ ++ + D G YTC A ++ Sbjct: 1940 VTLECQSQAVPPPVLSWRKDGHALSPRPGVHLSADGVLLQVERAEVQDVGRYTCEALNKA 1999 Query: 474 GK 475 G+ Sbjct: 2000 GR 2001 Score = 150 bits (363), Expect = 3e-34 Identities = 134/507 (26%), Positives = 215/507 (42%), Gaps = 22/507 (4%) Query: 4 DYVTSGEAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62 D V P IE L + V + A+L C A G P+P I WY+G + S + Sbjct: 1729 DVVLKVLVPPNIEPGLVNKAVLENTSASLECLASGVPTPRISWYRGRQPISSKPGLMVSS 1788 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122 G + LR ++ SDAG Y C A+N G++ + L + V L P Sbjct: 1789 DGRV--LRIKRAQL-SDAGSYRCVASNVAGSSELKFG-LRINV-PPRITLAPSLPGPVLL 1843 Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCI 181 + V G+P P + W K+G + G S + + GG+ L + +R TDAG Y C+ Sbjct: 1844 NEPVRLVCNATGAPTPMLMWLKDGNPVSATGTSGLQIFPGGHVLTLAGSRATDAGTYTCV 1903 Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241 A NA G + TL++H+ P ++ ++V SVT +C+ P P + WR+ G Sbjct: 1904 AVNAVGEDRRDV-TLQVHLPPSILGEEQNVSVVVNQSVTLECQSQAVPPPVLSWRKD-GH 1961 Query: 242 GNMPLGRVKVLDDGSL-RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL-SP 299 P V + DG L +++ + D G Y+CEA N G L V+ PP + P Sbjct: 1962 ALSPRPGVHLSADGVLLQVERAEVQDVGRYTCEALNKAGRSEKHYNLNVWVPPEFSFWEP 2021 Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359 ++ V G+ +C G P P + W +G + G S + A +L + Sbjct: 2022 RTLAVTEGHPVSLSCECWGIPFPKITWKKDG-MLVPTDGGSTEPISAVG-----RLLYLG 2075 Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419 + N C N AG+S L V P ++ ++ C Sbjct: 2076 KAQPSQEGN-YTCECSNIAGNSSQEQHLEVYVAPKVPGS--SDFHKEVSVIHSGEVTLEC 2132 Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKYVW 478 A P P++ W +G+ + ++ + + G L ++ + +G YTC+A + G+ Sbjct: 2133 EATGKPPPVVTWEKDGQLVTRDQGLLLQHRGRALQVEQARAAHAGRYTCIAENEAGRAEQ 2192 Query: 479 SGALLVDSPINPNIHFFRAADVSSLPG 505 L V +P I +FR + S PG Sbjct: 2193 RFDLSVLGNPSPLIRWFRGEEPIS-PG 2218 Score = 146 bits (353), Expect = 4e-33 Identities = 140/492 (28%), Positives = 195/492 (39%), Gaps = 35/492 (7%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRA-GGSPSPAIRWYKGGVLVVSDTHRSILPAG 64 V E P I V V QPA+L C G P P W K G + S + SI G Sbjct: 789 VIGHEPPQIASSASMVRVLEGQPASLPCVVLAGKPFPQRHWLKEGQPLPSSRY-SIRTDG 847 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124 RA + DAG Y C TN+ G+ R ++ L V VL + +G Sbjct: 848 SFHIDRA----LQEDAGRYSCVVTNTVGSQR-QDIELAVQVLPSILPTASHYVTN-EGVP 901 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 + L C+ RG P P + W+K L S ++ G+L + D+G Y C A N Sbjct: 902 ISLPCVS-RGIPTPTITWRKETNALS-PRSSHHQVLKEGSLYLPQPSAQDSGTYVCTATN 959 Query: 185 AAGTRESAIATLKIHIKPYLITG-------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 A G I L ++ KP +I P + A G +T C G P P + W + Sbjct: 960 ALGISSQEIQ-LSVNTKPRIIMNESLDSDRPVTITALAGKELTLHCEAEGSPSPLITWTK 1018 Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297 + + R +L GSL+L + D G Y+C A N G S S L V PP I Sbjct: 1019 DSQLLSPITDRHSLLPSGSLKLAETSVEDNGLYTCIASNPAGTASRSYVLGVQVPPQIQQ 1078 Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 P + V +G TC ATG P+P + WS +G I P + + V V Sbjct: 1079 GPQLLKVLAGESLDLTCVATGDPKPQLRWSKDG---ITLPQKGWVGPDGSVHLESVQV-- 1133 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417 +DS + C A + AG +L V + P + + A Sbjct: 1134 ------SDSGH-YHCVASSEAGEDARELELEVL---EPPRWEAEDAEALLERVAGENASL 1183 Query: 418 PCTAICTPEPIIAWYFE--GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 PC TP P + W + E L +V ND +L + + DSG Y C A++ G Sbjct: 1184 PCPVTGTPTPRVIWRKDPAPELLSSQPGLSVLNDSSLFIASVSSQDSGDYECRATNEVGS 1243 Query: 476 YVWSGALLVDSP 487 L+V P Sbjct: 1244 VSRKVKLVVYVP 1255 Score = 141 bits (341), Expect = 1e-31 Identities = 137/522 (26%), Positives = 221/522 (42%), Gaps = 35/522 (6%) Query: 20 DVTVAR-HQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS 78 D TV R A L+C + P P I WYK G + D L G L + +V + Sbjct: 2679 DTTVVRVGDTAVLHCESDTLPEPVITWYKNGQQIALDQQVQTLLDGQK--LEIVNVQV-A 2735 Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138 D G+Y C+ +N G A R L V V E E+ G+ +VL C G P P Sbjct: 2736 DKGLYSCKVSNIVGEA-IRTFVLIVQVPPIFENPEKETLSQVAGNPLVLVC-DVAGVPAP 2793 Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198 V W K+ + + R + GG L + + + G Y C+A N + + Sbjct: 2794 TVTWLKD-RMPVESSVERGVVSRGGRLQLSRLQPSQEGTYTCVAENPEAEARKDFVVMVL 2852 Query: 199 HIKPYLITG-PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDG- 255 L +G P++ V +C G P PD+ W + G ++ DG Sbjct: 2853 VAPRILSSGVPQEHNILEEQEVRLECEAEGQPQPDISWLKDGRPLGVHTAPHLRFYTDGS 2912 Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI----NLSPNSVNVESGNVAR 311 SL L + +D G Y+C A+NSVG + ++V PP+I N S N ++V+ G + Sbjct: 2913 SLVLKGLKSSDSGAYTCLAQNSVGEDTKLHTVSVLVPPTIERGANGSENLISVQ-GELVT 2971 Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371 C A G P + W +G + P R H++ L I+ D+ T Sbjct: 2972 MACPARGSPPIQINWLKDG---LPMPLSQRTHLHSSG-----RTLRISQVQVADA-GTFT 3022 Query: 372 CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEPII 429 C A + AG + L + PP++ + + + S PC A +P P + Sbjct: 3023 CVASSPAGVAERTFSLQI-----HVPPVLEPSETKDAMAVVRGSDVTLPCEARGSPLPAV 3077 Query: 430 AWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPIN 489 +W +G +L+ R + + +L L+ + D GTY+CVA + G+ L V P Sbjct: 3078 SWLKDGASLML-QRLGLGSGSSLQLEAVQADDVGTYSCVAINEAGEATRHFQLAVMEP-- 3134 Query: 490 PNIH-FFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530 P+I +A ++ LPG P + I + + ++W ++ ++ Sbjct: 3135 PHIEDSGQAEEMLLLPGAPLELICNALGSPMPNITWQKDGQV 3176 Score = 138 bits (333), Expect = 1e-30 Identities = 129/475 (27%), Positives = 193/475 (40%), Gaps = 40/475 (8%) Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86 + A L C+A G P P + WY+GG+ ++ + G ++ R DAG Y C+ Sbjct: 625 EEAVLECKASGVPPPRVIWYRGGLEMILAPE---VAHTGTLRIQEVQER---DAGNYICK 678 Query: 87 ATNSYGTARSRNATLHVAVLREEFRLEPESKQSA--QGDTVVLECLPPRGSPEPNVYWKK 144 A N G A S + L V RL S+ G +L C G P P + W + Sbjct: 679 AVNELGAA-SADIRLEVGYAP---RLVESSRNMVVEMGRNAILACRA-EGRPSPRITWAR 733 Query: 145 -NGQTLLFDG--DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI-HI 200 +G+ + +R ++ G L +++ D Y C A N G ++ + I H Sbjct: 734 VDGKPVPAHPVEGNRARQLEAGVLFLENVTPEDQALYICEAHNTFGKAQAEVQLTVIGHE 793 Query: 201 KPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL 259 P + + V G + C V G P P W + G +P R + DGS + Sbjct: 794 PPQIASSASMVRVLEGQPASLPCVVLAGKPFPQRHWLKE--GQPLPSSRYSIRTDGSFHI 851 Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGR 319 D + D G YSC N+VG+ L V PSI + + G C + G Sbjct: 852 DRALQEDAGRYSCVVTNTVGSQRQDIELAVQVLPSILPTASHYVTNEGVPISLPCVSRGI 911 Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379 P PT+ W E N +S H + +G L + DS T VC+A N G Sbjct: 912 PTPTITWRKETN------ALSPRSSHHQVLKEG--SLYLPQPSAQDS-GTYVCTATNALG 962 Query: 380 SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV------FPCTAICTPEPIIAWYF 433 S +L+V + P II N + P+ A+ C A +P P+I W Sbjct: 963 ISSQEIQLSVNT----KPRIIMNESLDSDRPVTITALAGKELTLHCEAEGSPSPLITWTK 1018 Query: 434 EGEALIQ-NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 + + L R ++ G+L L + D+G YTC+AS+ G S L V P Sbjct: 1019 DSQLLSPITDRHSLLPSGSLKLAETSVEDNGLYTCIASNPAGTASRSYVLGVQVP 1073 Score = 129 bits (311), Expect = 5e-28 Identities = 136/504 (26%), Positives = 208/504 (41%), Gaps = 41/504 (8%) Query: 2 SDDYVTSGEAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI 60 S YV + P I+Q P + V + L C A G P P +RW K G+ + + Sbjct: 1063 SRSYVLGVQVPPQIQQGPQLLKVLAGESLDLTCVATGDPKPQLRWSKDGITL---PQKGW 1119 Query: 61 LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS- 119 + G L + SD+G Y C A++ G +R L V E R E E ++ Sbjct: 1120 VGPDGSVHLESVQV---SDSGHYHCVASSEAGED-ARELELEVL---EPPRWEAEDAEAL 1172 Query: 120 ---AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAG 176 G+ L C P G+P P V W+K+ L + +++ +L I D+G Sbjct: 1173 LERVAGENASLPC-PVTGTPTPRVIWRKDPAPELLSSQPGLSVLNDSSLFIASVSSQDSG 1231 Query: 177 RYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSS--VTFQCRVGGDPLPDVL 234 Y+C A N G+ + L +++ P+ + V T +S +T C V G P P + Sbjct: 1232 DYECRATNEVGSVSRKVK-LVVYVPPHFRGEEQRVNVSTLASRPLTLNCDVSGFPTPAIT 1290 Query: 235 WRRSAGGGNMPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292 W + G + DG SL V +D Y+C+A N G L V P Sbjct: 1291 WYKD--GRPVSEDNRHYFPDGAPSLHFPQVQKSDSDLYTCQAVNPAGMAQKDFNLLVLIP 1348 Query: 293 PSINLSPNSVNVE--SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350 PS+ + + V +G C +G P P + W+ +G + PG H V Sbjct: 1349 PSVRGAGTAQEVSRLAGLEVELECRTSGVPLPQVEWTKDGQP--VAPGDP----HIQLVE 1402 Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410 DG VL I + D+ + C A + AG +L++ + PP I + + + Sbjct: 1403 DG-QVLKIPSSHLGDAGH-YQCVAFSPAGQQAKDFQLSIQT----PPTIWGSNETGEVAV 1456 Query: 411 IKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCV 468 ++ V C A P P I W +G+ L + R G L L SDSG YTC Sbjct: 1457 MEDHVVRLQCDARGVPTPAITWLKDGDPLHASPRVAYAKGGRHLQLGRARGSDSGLYTCQ 1516 Query: 469 ASSRHGKYVWSGALLVDSPINPNI 492 AS+ G + A+ +D + P I Sbjct: 1517 ASNAAG--IAEKAVRLDVYVPPTI 1538 Score = 129 bits (311), Expect = 5e-28 Identities = 143/543 (26%), Positives = 217/543 (39%), Gaps = 65/543 (11%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89 L CR G P P + W K G V D H ++ G + + ++H DAG Y C A + Sbjct: 1370 LECRTSGVPLPQVEWTKDGQPVAPGDPHIQLVEDGQVLKIPSSH---LGDAGHYQCVAFS 1426 Query: 90 SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV-LECLPPRGSPEPNVYWKKNGQT 148 G ++++ L + + + + D VV L+C RG P P + W K+G Sbjct: 1427 PAGQ-QAKDFQLSIQTPPTIWGSNETGEVAVMEDHVVRLQC-DARGVPTPAITWLKDGDP 1484 Query: 149 LLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT- 206 L R+ GG +L + AR +D+G Y C A NAAG E A+ L +++ P + Sbjct: 1485 L--HASPRVAYAKGGRHLQLGRARGSDSGLYTCQASNAAGIAEKAVR-LDVYVPPTIEGA 1541 Query: 207 --GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG------------GGN----MPLGR 248 GP V A G + C G P P + W + GG + GR Sbjct: 1542 DGGPLVVKAVAGRPLALGCSASGHPPPTLTWHQDENPLTENNGTWLQEGGRVLRWLRNGR 1601 Query: 249 -------VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN-LSP 299 V+V DG+ LR+D+V G ++C+A N G A + V++ PS+ L Sbjct: 1602 PAEEFAGVEVSTDGAMLRIDHVQPDHNGLFACQATNEAGTAGAEVEVLVHEQPSVTVLEG 1661 Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359 ++ C A G P P + W G + G L I Sbjct: 1662 ENITAPFLQPVTIQCVAAGMPVPNLSWWKNGVSLVTTGGS----------------LQIE 1705 Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419 D D N C A N AG + L V PP I G N+ + + A C Sbjct: 1706 KVDLRDEGN-YTCVATNLAGEAKRDVVLKVLV-----PPNIEPGLVNKAVLENTSASLEC 1759 Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHGKYVW 478 A P P I+WY + + V++DG ++ +K SD+G+Y CVAS+ G Sbjct: 1760 LASGVPTPRISWYRGRQPISSKPGLMVSSDGRVLRIKRAQLSDAGSYRCVASNVAGSSEL 1819 Query: 479 SGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSW-SQNNKIGSSSILG 537 L ++ P P I + L P + + + + L W N + ++ G Sbjct: 1820 KFGLRINVP--PRITLAPSLPGPVLLNEPVRLVCNATGAPTPMLMWLKDGNPVSATGTSG 1877 Query: 538 YQV 540 Q+ Sbjct: 1878 LQI 1880 Score = 124 bits (298), Expect = 2e-26 Identities = 117/409 (28%), Positives = 166/409 (40%), Gaps = 30/409 (7%) Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ----GDTVVLECLPPR 133 SD G Y CEA N G R + L + P ++ GDT VL C Sbjct: 2640 SDTGTYTCEALNVAG--RDQKLVLLSVFAPPTIKQTPGGQRDTTVVRVGDTAVLHCESDT 2697 Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193 PEP + W KNGQ + D + L+DG L I + + D G Y C N G AI Sbjct: 2698 -LPEPVITWYKNGQQIALDQQVQT-LLDGQKLEIVNVQVADKGLYSCKVSNIVG---EAI 2752 Query: 194 ATLKIHIK-PYLITGPE-DVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250 T + ++ P + PE + ++Q G+ + C V G P P V W + + R Sbjct: 2753 RTFVLIVQVPPIFENPEKETLSQVAGNPLVLVCDVAGVPAPTVTWLKDRMPVESSVERGV 2812 Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS--PNSVNVESGN 308 V G L+L + + EG Y+C AEN + V P I S P N+ Sbjct: 2813 VSRGGRLQLSRLQPSQEGTYTCVAENPEAEARKDFVVMVLVAPRILSSGVPQEHNILEEQ 2872 Query: 309 VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368 R C A G+P+P + W +G P H DG + L + +DS Sbjct: 2873 EVRLECEAEGQPQPDISWLKDGR-----PLGVHTAPHLRFYTDG-SSLVLKGLKSSDS-G 2925 Query: 369 TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII--TNGPSNQTLPIKSMAVFPCTAICTPE 426 C A N G ++V PP I NG N + C A +P Sbjct: 2926 AYTCLAQNSVGEDTKLHTVSVLV----PPTIERGANGSENLISVQGELVTMACPARGSPP 2981 Query: 427 PIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474 I W +G + + R ++ + G TL + + +D+GT+TCVASS G Sbjct: 2982 IQINWLKDGLPMPLSQRTHLHSSGRTLRISQVQVADAGTFTCVASSPAG 3030 Score = 123 bits (297), Expect = 3e-26 Identities = 100/318 (31%), Positives = 147/318 (46%), Gaps = 22/318 (6%) Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74 IEQ L + R+ C A + A +K +L+V T IL +G L RA+ Sbjct: 3560 IEQALPIHTGRY-----TCTARNAAGVA---HKHVILMVQGTGAQILSSGQLRISRASA- 3610 Query: 75 RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRG 134 DAG Y C A N GTA + T V + + +A+G +L C+ +G Sbjct: 3611 ---EDAGNYLCIAKNPSGTALGK--TRLVVQVPPVIKGGHSDLSAAEGSQALLPCI-AQG 3664 Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194 PEP++ WKK+G ++ + + + G L+++++ + DAG Y CIA NAAG S Sbjct: 3665 IPEPHITWKKDG-FVVPSMEGKYTIQPSGELLVKNSERRDAGTYTCIAENAAG-HTSRRV 3722 Query: 195 TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254 L I P T P D+ G + +C G P P + W + + V D Sbjct: 3723 HLSILSLPTFTTLPGDLSLNHGDRLWLRCTARGSPTPHISWMVN---NRLVKEGVLEQDG 3779 Query: 255 GS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE-SGNVARF 312 GS L+ V D G Y+C AEN VG V A ++ V + P++ +S VE G+ AR Sbjct: 3780 GSTLQRAAVTREDSGTYTCWAENIVGKVQAVSFVHVKEAPALQGEASSHLVELLGDSARL 3839 Query: 313 TCTATGRPEPTMFWSVEG 330 C A G P P + W +G Sbjct: 3840 DCAARGDPAPVIRWIKDG 3857 Score = 122 bits (293), Expect = 8e-26 Identities = 128/463 (27%), Positives = 186/463 (40%), Gaps = 39/463 (8%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 ++T QP T+ C A G P P + W+K GV S++ GG + R D Sbjct: 1663 NITAPFLQPVTIQCVAAGMPVPNLSWWKNGV--------SLVTTGGSLQIEKVDLR---D 1711 Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP--ESKQSAQGDTVVLECLPPRGSPE 137 G Y C ATN G A+ R+ L V V +EP +K + + LECL G P Sbjct: 1712 EGNYTCVATNLAGEAK-RDVVLKVLV---PPNIEPGLVNKAVLENTSASLECL-ASGVPT 1766 Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197 P + W + G+ + M DG L I+ A+ +DAG Y+C+A N AG+ E L+ Sbjct: 1767 PRISWYR-GRQPISSKPGLMVSSDGRVLRIKRAQLSDAGSYRCVASNVAGSSELKFG-LR 1824 Query: 198 IHIKPYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP-LGRVKVLDDG 255 I++ P + P V C G P P ++W + + +++ G Sbjct: 1825 INVPPRITLAPSLPGPVLLNEPVRLVCNATGAPTPMLMWLKDGNPVSATGTSGLQIFPGG 1884 Query: 256 S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314 L L D G Y+C A N+VG L V+ PPSI +V+V C Sbjct: 1885 HVLTLAGSRATDAGTYTCVAVNAVGEDRRDVTLQVHLPPSILGEEQNVSVVVNQSVTLEC 1944 Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374 + P P + W +G+ PG+ H +A DGV +L + + D C A Sbjct: 1945 QSQAVPPPVLSWRKDGHALSPRPGV-----HLSA--DGV-LLQVERAEVQDV-GRYTCEA 1995 Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFE 434 +N AG S L V PP P + C P P I W + Sbjct: 1996 LNKAGRSEKHYNLNVWV----PPEFSFWEPRTLAVTEGHPVSLSCECWGIPFPKITWKKD 2051 Query: 435 GEALIQN--HRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHG 474 G + + ++ G L+ L S G YTC S+ G Sbjct: 2052 GMLVPTDGGSTEPISAVGRLLYLGKAQPSQEGNYTCECSNIAG 2094 Score = 115 bits (276), Expect = 9e-24 Identities = 116/428 (27%), Positives = 181/428 (42%), Gaps = 39/428 (9%) Query: 29 ATLNCRAGGSPSPAIRWYKGGV--LVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86 A+L C G+P+P + W K L+ S S+L LF + D+G Y C Sbjct: 1181 ASLPCPVTGTPTPRVIWRKDPAPELLSSQPGLSVLNDSSLFIASVSS----QDSGDYECR 1236 Query: 87 ATNSYGTARSRNATLHVAVLREEFRLEPE--SKQSAQGDTVVLECLPPRGSPEPNVYWKK 144 ATN G+ SR L V + FR E + + + + L C G P P + W K Sbjct: 1237 ATNEVGSV-SRKVKL-VVYVPPHFRGEEQRVNVSTLASRPLTLNC-DVSGFPTPAITWYK 1293 Query: 145 NGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY 203 +G+ + D+R + DG +L +++D+ Y C A N AG + L + I P Sbjct: 1294 DGRPV--SEDNRHYFPDGAPSLHFPQVQKSDSDLYTCQAVNPAGMAQKDF-NLLVLIPPS 1350 Query: 204 LITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLD 260 + ++V G V +CR G PLP V W + +++++DG L++ Sbjct: 1351 VRGAGTAQEVSRLAGLEVELECRTSGVPLPQVEWTKDGQPVAPGDPHIQLVEDGQVLKIP 1410 Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNVESGNVARFTCTATG 318 + L D G Y C A + G + L++ PP+I + V V +V R C A G Sbjct: 1411 SSHLGDAGHYQCVAFSPAGQQAKDFQLSIQTPPTIWGSNETGEVAVMEDHVVRLQCDARG 1470 Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378 P P + W +G+ P ++ K G L + +DS C A N A Sbjct: 1471 VPTPAITWLKDGDPLHASPRVAYAK--------GGRHLQLGRARGSDS-GLYTCQASNAA 1521 Query: 379 GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP----CTAICTPEPIIAWYFE 434 G + + V D PP I G L +K++A P C+A P P + W+ + Sbjct: 1522 GIA----EKAVRLDVYVPPTI--EGADGGPLVVKAVAGRPLALGCSASGHPPPTLTWHQD 1575 Query: 435 GEALIQNH 442 L +N+ Sbjct: 1576 ENPLTENN 1583 Score = 112 bits (269), Expect = 6e-23 Identities = 96/367 (26%), Positives = 152/367 (41%), Gaps = 26/367 (7%) Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT 173 P++ + G+T +L C +P N+ W ++ + L + L + +L I + Sbjct: 435 PQNVTVSPGETALLSCQVLDKAPY-NLTWVRDWRVLPASPGRVVQLANL-SLEISGIIPS 492 Query: 174 DAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233 D G+YQC+A NA G +++ L I P + G + C G P P + Sbjct: 493 DGGKYQCLASNANGITRASVWLL-IREPPQISINTSSRHFSQGVELRISCTASGYPPPHI 551 Query: 234 LWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293 WR + M GR V D G+L + +V D G YSC+A N VG + L +PP Sbjct: 552 SWRHNDQTIGMD-GRFLVDDQGTLIIQSVTPEDAGNYSCQATNEVGTDEQTVTLFYTEPP 610 Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353 S++ V G A C A+G P P + W G I+ P ++ Sbjct: 611 SVSALRPVVLAPIGEEAVLECKASGVPPPRVIWYRGGLEMILAPEVAH-----------T 659 Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413 L I + + D+ N I C AVN G++ +L V P + N + + Sbjct: 660 GTLRIQEVQERDAGNYI-CKAVNELGAASADIRLEVGY-----APRLVESSRNMVVEMGR 713 Query: 414 MAVFPCTAICTPEPIIAWY-FEGEAL----IQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468 A+ C A P P I W +G+ + ++ +R G L L+++ D Y C Sbjct: 714 NAILACRAEGRPSPRITWARVDGKPVPAHPVEGNRARQLEAGVLFLENVTPEDQALYICE 773 Query: 469 ASSRHGK 475 A + GK Sbjct: 774 AHNTFGK 780 Score = 106 bits (254), Expect = 4e-21 Identities = 77/296 (26%), Positives = 121/296 (40%), Gaps = 16/296 (5%) Query: 159 LVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSS 218 ++ G L I A DAG Y CIA+N +GT L + + P + G D+ A GS Sbjct: 3597 ILSSGQLRISRASAEDAGNYLCIAKNPSGTALGK-TRLVVQVPPVIKGGHSDLSAAEGSQ 3655 Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSV 278 C G P P + W++ G+ + G L + N D G Y+C AEN+ Sbjct: 3656 ALLPCIAQGIPEPHITWKKDGFVVPSMEGKYTIQPSGELLVKNSERRDAGTYTCIAENAA 3715 Query: 279 GAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPG 338 G S +L++ P+ P +++ G+ CTA G P P + W V N ++ G Sbjct: 3716 GHTSRRVHLSILSLPTFTTLPGDLSLNHGDRLWLRCTARGSPTPHISWMV--NNRLVKEG 3773 Query: 339 MSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398 + DG + L + DS T C A N G + V P Sbjct: 3774 VLEQ--------DGGSTLQRAAVTREDS-GTYTCWAENIVGKVQAVSFVHV----KEAPA 3820 Query: 399 IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVL 454 + S+ + A C A P P+I W +G ++ +H ++ +G+L + Sbjct: 3821 LQGEASSHLVELLGDSARLDCAARGDPAPVIRWIKDGLPVLSSHHKHQLQNGSLAI 3876 Score = 105 bits (253), Expect = 6e-21 Identities = 77/295 (26%), Positives = 124/295 (42%), Gaps = 8/295 (2%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 AP I P V V+ ++ A L C+ G P + W K G+ +V + R + G ++ Sbjct: 3318 APTIQPGPSVVNVSVNETALLPCKTRGLPVSLVSWRKDGIPLVPGSPRLEFLSDGSLRIQ 3377 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130 + + D+G Y C+A+NS G+ R + L V P + L C Sbjct: 3378 PVYPQ---DSGYYLCQASNSAGSDR-QGRELRVFE-PPTIAPGPSNLTLTVHTQATLPC- 3431 Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMH-LVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189 RGSP+P+V WKKNGQTL D + L+ +LV+ D D +++C+ N AG Sbjct: 3432 EARGSPKPHVVWKKNGQTLSLDRHQEAYRLLPSSSLVLTDPDLQDTAQFECLVSNDAGET 3491 Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249 + + +++ P + D + V C G P P V W + Sbjct: 3492 RR-LFWVTVYVPPTIADDRTDFTVTKMAPVVLTCHTTGVPTPVVSWSKGGAQLGKRGSGY 3550 Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304 +V G+L ++ + G Y+C A N+ G L V + LS + + Sbjct: 3551 RVSPTGALEIEQALPIHTGRYTCTARNAAGVAHKHVILMVQGTGAQILSSGQLRI 3605 Score = 93.1 bits (221), Expect = 4e-17 Identities = 98/338 (28%), Positives = 138/338 (40%), Gaps = 34/338 (10%) Query: 30 TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89 +L C + P P I WYK G LV D +L G L + T D+G Y C ATN Sbjct: 2351 SLECESWAMPPPTITWYKDGQLVSPDNRLHLLADGRLLQINPTKAW---DSGRYLCVATN 2407 Query: 90 SYGTA-RSRNATLHVAVL-------REEFRLEP----------ESKQSAQGDTVVLECLP 131 G + N + V + E F + E ++ + + L C Sbjct: 2408 VAGEDDKDFNVLVQVPPIFQKIGDPNEAFEVHHQEEELRGGVLEYREIVENNPAYLYC-D 2466 Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191 P P + W K+ Q L D + L G L I R DAGRY C A N G E Sbjct: 2467 TNAVPPPQLTWYKDDQPLS-DIEGISVLQGGRVLQIPMVRSEDAGRYTCKASNEVG--ED 2523 Query: 192 AIATLKIHIKPYLITG-PEDVVAQT----GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 + + + P +I G PE++V + S+V QC+ G P P + W R+ G +P Sbjct: 2524 WLHYELLVLTPPVIQGDPEELVEEVTVNANSTVNLQCQALGTPTPVISWLRN-GLPFIPS 2582 Query: 247 GRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305 + + L+DG L++ AD Y C AENS G+ L V ++ L P + Sbjct: 2583 SKHQALEDGQVLQVSVADAADSASYMCVAENSAGSSEKLFTLKVQGTHTLQL-PRPKPSD 2641 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTI-IFPGMSRD 342 +G GR + + SV TI PG RD Sbjct: 2642 TGTYTCEALNVAGRDQKLVLLSVFAPPTIKQTPGGQRD 2679 Score = 89.0 bits (211), Expect = 7e-16 Identities = 98/337 (29%), Positives = 140/337 (41%), Gaps = 36/337 (10%) Query: 17 QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD--THRSILPAGGLFFLRATHG 74 +P + V P +L+C G P P I W K G+LV +D + I G L +L Sbjct: 2020 EPRTLAVTEGHPVSLSCECWGIPFPKITWKKDGMLVPTDGGSTEPISAVGRLLYLGKAQ- 2078 Query: 75 RVHSDAGVYWCEATNSYG-TARSRNATLHVAVL---REEFRLEPESKQSAQGDTVVLECL 130 S G Y CE +N G +++ ++ ++VA +F E S + V LEC Sbjct: 2079 --PSQEGNYTCECSNIAGNSSQEQHLEVYVAPKVPGSSDFHKEVSVIHSGE---VTLEC- 2132 Query: 131 PPRGSPEPNVYWKKNGQTLLFD-GDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189 G P P V W+K+GQ + D G H G L ++ AR AGRY CIA N AG Sbjct: 2133 EATGKPPPVVTWEKDGQLVTRDQGLLLQH--RGRALQVEQARAAHAGRYTCIAENEAGRA 2190 Query: 190 ESAIATLKIHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 E + LI G E + G V F GG L + GG M L Sbjct: 2191 EQRFDLSVLGNPSPLIRWFRGEEPI--SPGEDVYF--LAGGRILKLTRVQEEEGGLYMCL 2246 Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306 +L+ + + G YSC A NSV + L+V + + +N + Sbjct: 2247 ANGSLLE-----ILQANFSSSGHYSCIASNSVSEKTKHYKLSVLGTHGLQI----LNAQE 2297 Query: 307 GNVARFTCTATGR-PEPTMFWSVEGNRTIIFPGMSRD 342 + R+TC T E + VE +I P +S+D Sbjct: 2298 QDAGRYTCVVTNEVGEAVKNYHVE---VLIPPSISKD 2331 Score = 86.2 bits (204), Expect = 5e-15 Identities = 103/358 (28%), Positives = 146/358 (40%), Gaps = 57/358 (15%) Query: 59 SILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ 118 S+L GL L A DAG Y C TN G A +N + V + + +P + Sbjct: 2283 SVLGTHGLQILNAQE----QDAGRYTCVVTNEVGEA-VKNYHVEVLIPPSISKDDPLDEF 2337 Query: 119 SAQ------GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDAR 171 S + T+ LEC P P + W K+GQ L D+R+HL+ DG L I + Sbjct: 2338 SVKEVKAKVNSTLSLEC-ESWAMPPPTITWYKDGQ--LVSPDNRLHLLADGRLLQINPTK 2394 Query: 172 QTDAGRYQCIARNAAGTRESAIATLKIHIKPYL--ITGPEDVV-------AQTGSSVTFQ 222 D+GRY C+A N AG + L + + P I P + G + ++ Sbjct: 2395 AWDSGRYLCVATNVAGEDDKDFNVL-VQVPPIFQKIGDPNEAFEVHHQEEELRGGVLEYR 2453 Query: 223 -----------CRVGGDPLPDVLWRRSAGGGNMPLGRVK---VLDDGS-LRLDNVILADE 267 C P P + W + + PL ++ VL G L++ V D Sbjct: 2454 EIVENNPAYLYCDTNAVPPPQLTWYKD----DQPLSDIEGISVLQGGRVLQIPMVRSEDA 2509 Query: 268 GEYSCEAENSVGAVSASGYLTVYDPPSINLSP----NSVNVESGNVARFTCTATGRPEPT 323 G Y+C+A N VG L V PP I P V V + + C A G P P Sbjct: 2510 GRYTCKASNEVGEDWLHYELLVLTPPVIQGDPEELVEEVTVNANSTVNLQCQALGTPTPV 2569 Query: 324 MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381 + W G P + K+ A+ DG VL ++ D DS + +C A N AGSS Sbjct: 2570 ISWLRNG-----LPFIPSSKHQ--ALEDG-QVLQVSVADAADSA-SYMCVAENSAGSS 2618 Score = 82.6 bits (195), Expect = 6e-14 Identities = 67/226 (29%), Positives = 96/226 (42%), Gaps = 15/226 (6%) Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309 ++L G LR+ D G Y C A+N G L V PP I + ++ G+ Sbjct: 3596 QILSSGQLRISRASAEDAGNYLCIAKNPSGTALGKTRLVVQVPPVIKGGHSDLSAAEGSQ 3655 Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369 A C A G PEP + W +G + P M KY T G L + ++++ D+ T Sbjct: 3656 ALLPCIAQGIPEPHITWKKDG---FVVPSM-EGKY--TIQPSG--ELLVKNSERRDA-GT 3706 Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429 C A N AG + R L++ S P T P + +L CTA +P P I Sbjct: 3707 YTCIAENAAGHTSRRVHLSILS-----LPTFTTLPGDLSLNHGDRLWLRCTARGSPTPHI 3761 Query: 430 AWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 +W L++ TL + + DSGTYTC A + GK Sbjct: 3762 SWMVNNR-LVKEGVLEQDGGSTLQRAAVTREDSGTYTCWAENIVGK 3806 Score = 77.0 bits (181), Expect = 3e-12 Identities = 87/343 (25%), Positives = 127/343 (37%), Gaps = 49/343 (14%) Query: 165 LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP-------EDVVAQTGS 217 L I +A++ DAGRY C+ N G +++ I P + ++V A+ S Sbjct: 2290 LQILNAQEQDAGRYTCVVTNEVGEAVKNYH-VEVLIPPSISKDDPLDEFSVKEVKAKVNS 2348 Query: 218 SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA-DEGEYSCEAEN 276 +++ +C P P + W + G P R+ +L DG L N A D G Y C A N Sbjct: 2349 TLSLECESWAMPPPTITWYKD-GQLVSPDNRLHLLADGRLLQINPTKAWDSGRYLCVATN 2407 Query: 277 SVGAVSASGYLTVYDPPSINL--SPNSV------------------NVESGNVARFTCTA 316 G + V PP PN + N A C Sbjct: 2408 VAGEDDKDFNVLVQVPPIFQKIGDPNEAFEVHHQEEELRGGVLEYREIVENNPAYLYCDT 2467 Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376 P P + W + G+S V G VL I D+ C A N Sbjct: 2468 NAVPPPQLTWYKDDQPLSDIEGIS--------VLQGGRVLQIPMVRSEDA-GRYTCKASN 2518 Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ----TLPIKSMAVFPCTAICTPEPIIAWY 432 G ++ +L V + PP+I P T+ S C A+ TP P+I+W Sbjct: 2519 EVGEDWLHYELLVLT-----PPVIQGDPEELVEEVTVNANSTVNLQCQALGTPTPVISWL 2573 Query: 433 FEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474 G I + + DG L + D +DS +Y CVA + G Sbjct: 2574 RNGLPFIPSSKHQALEDGQVLQVSVADAADSASYMCVAENSAG 2616 Score = 67.7 bits (158), Expect = 2e-09 Identities = 65/241 (26%), Positives = 101/241 (41%), Gaps = 22/241 (9%) Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297 ++ G + L +KV +L+L +D G Y+CEA N G L+V+ PP+I Sbjct: 2613 NSAGSSEKLFTLKVQGTHTLQLPRPKPSDTGTYTCEALNVAGRDQKLVLLSVFAPPTIKQ 2672 Query: 298 SP----NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353 +P ++ V G+ A C + PEP + W G + ++ D+ T + DG Sbjct: 2673 TPGGQRDTTVVRVGDTAVLHCESDTLPEPVITWYKNGQQ------IALDQQVQT-LLDGQ 2725 Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP--I 411 + +N + + C N G + L V + PPI N P +TL Sbjct: 2726 KLEIVN--VQVADKGLYSCKVSNIVGEAIRTFVLIV-----QVPPIFEN-PEKETLSQVA 2777 Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN-VTNDGTLVLKDLDKSDSGTYTCVAS 470 + V C P P + W + + + R V+ G L L L S GTYTCVA Sbjct: 2778 GNPLVLVCDVAGVPAPTVTWLKDRMPVESSVERGVVSRGGRLQLSRLQPSQEGTYTCVAE 2837 Query: 471 S 471 + Sbjct: 2838 N 2838 Score = 64.9 bits (151), Expect = 1e-08 Identities = 54/207 (26%), Positives = 82/207 (39%), Gaps = 9/207 (4%) Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82 + + PA L C P P + WYK + S+L G + + DAG Sbjct: 2455 IVENNPAYLYCDTNAVPPPQLTWYKDDQPLSDIEGISVLQGGRVLQIPMVRSE---DAGR 2511 Query: 83 YWCEATNSYGT--ARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140 Y C+A+N G L V++ + E TV L+C G+P P + Sbjct: 2512 YTCKASNEVGEDWLHYELLVLTPPVIQGDPEELVEEVTVNANSTVNLQC-QALGTPTPVI 2570 Query: 141 YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200 W +NG + L DG L + A D+ Y C+A N+AG+ E + TLK+ Sbjct: 2571 SWLRNGLPFI-PSSKHQALEDGQVLQVSVADAADSASYMCVAENSAGSSEK-LFTLKVQ- 2627 Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGG 227 + + P + TG+ V G Sbjct: 2628 GTHTLQLPRPKPSDTGTYTCEALNVAG 2654 Score = 53.2 bits (122), Expect = 4e-05 Identities = 68/268 (25%), Positives = 105/268 (39%), Gaps = 42/268 (15%) Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN-------LSPN 300 ++ VL L++ N D G Y+C N VG + ++ V PPSI+ S Sbjct: 2281 KLSVLGTHGLQILNAQEQDAGRYTCVVTNEVGEAVKNYHVEVLIPPSISKDDPLDEFSVK 2340 Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360 V + + C + P PT+ W +G ++ P ++ H A DG +L IN Sbjct: 2341 EVKAKVNSTLSLECESWAMPPPTITWYKDGQ--LVSPD---NRLHLLA--DG-RLLQINP 2392 Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN-GPSNQTLPI-------- 411 T DS +C A N AG + V + PPI G N+ + Sbjct: 2393 TKAWDS-GRYLCVATNVAGEDDKDFNVLV-----QVPPIFQKIGDPNEAFEVHHQEEELR 2446 Query: 412 -----------KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS 460 + A C P P + WY + + L +V G ++ + +S Sbjct: 2447 GGVLEYREIVENNPAYLYCDTNAVPPPQLTWYKDDQPLSDIEGISVLQGGRVLQIPMVRS 2506 Query: 461 -DSGTYTCVASSRHGKYVWSGALLVDSP 487 D+G YTC AS+ G+ LLV +P Sbjct: 2507 EDAGRYTCKASNEVGEDWLHYELLVLTP 2534 Score = 49.6 bits (113), Expect = 5e-04 Identities = 47/159 (29%), Positives = 67/159 (42%), Gaps = 15/159 (9%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P P D+++ L C A GSP+P I W LV + GG RA Sbjct: 3730 PTFTTLPGDLSLNHGDRLWLRCTARGSPTPHISWMVNNRLVKEGV---LEQDGGSTLQRA 3786 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ---SAQGDTVVLE 128 R D+G Y C A N G ++ + +HV +E L+ E+ GD+ L+ Sbjct: 3787 AVTR--EDSGTYTCWAENIVGKVQA-VSFVHV---KEAPALQGEASSHLVELLGDSARLD 3840 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVI 167 C RG P P + W K+G +L H + G+L I Sbjct: 3841 C-AARGDPAPVIRWIKDGLPVL--SSHHKHQLQNGSLAI 3876 Score = 46.0 bits (104), Expect = 0.006 Identities = 30/91 (32%), Positives = 41/91 (45%), Gaps = 5/91 (5%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPA 63 +VT P I + D TV + P L C G P+P + W KGG L + + P Sbjct: 3496 WVTVYVPPTIADDRTDFTVTKMAPVVLTCHTTGVPTPVVSWSKGGAQLGKRGSGYRVSPT 3555 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTA 94 G L +A +H+ G Y C A N+ G A Sbjct: 3556 GALEIEQAL--PIHT--GRYTCTARNAAGVA 3582 Score = 41.9 bits (94), Expect = 0.10 Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 6/89 (6%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 V G+ ++E+ VTV + L C+A G+P+P I W + G+ + + L G Sbjct: 2536 VIQGDPEELVEE---VTVNANSTVNLQCQALGTPTPVISWLRNGLPFIPSSKHQALEDGQ 2592 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTA 94 + + +D+ Y C A NS G++ Sbjct: 2593 VLQVSVADA---ADSASYMCVAENSAGSS 2618 >UniRef50_UPI00004D4C52 Cluster: Roundabout homolog 4 precursor (Magic roundabout).; n=1; Xenopus tropicalis|Rep: Roundabout homolog 4 precursor (Magic roundabout). - Xenopus tropicalis Length = 986 Score = 166 bits (404), Expect = 3e-39 Identities = 87/193 (45%), Positives = 114/193 (59%), Gaps = 8/193 (4%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT----HRSI--LPAGG 65 P IIE P D+ V + +PATL CRA G+P P I WY+ G V + T RS LP G Sbjct: 6 PRIIEHPSDLFVKKDKPATLYCRAEGNPQPTIEWYRNGEHVETSTDDKTQRSYVQLPEGP 65 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 LFF + SD G+Y C A N GTA SRNA+L+VA LR++FRL P A G + Sbjct: 66 LFFFSLNQRKGKSDEGIYTCVARNHLGTAFSRNASLYVAALRDDFRLNPSDAVVAVGKQL 125 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 +ECLPP+G PEPNV WKK+G + + ++ + + G L I A +TD+G Y C+A N Sbjct: 126 EIECLPPKGHPEPNVTWKKDG--IPINHNNSRYTISAGKLFIGKALKTDSGLYSCLASNQ 183 Query: 186 AGTRESAIATLKI 198 G RES A + + Sbjct: 184 VGERESRAAKIVV 196 Score = 78.2 bits (184), Expect = 1e-12 Identities = 87/320 (27%), Positives = 141/320 (44%), Gaps = 24/320 (7%) Query: 636 VELIEATPIDSKTIKLMWEILNFY-YLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEI 694 V L T + S ++ + W++L + EG +++R L + E+ T N+ S I Sbjct: 212 VHLDNITALPSASVYVHWQVLTESPFTEGYSVFYRTLSSTESEWTEWTKSRINEYSTV-I 270 Query: 695 TSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILN--TTTVHLKW 752 SL + KYEF + PF K G SN + + ++VP+ P NI + + T+ + W Sbjct: 271 PSLWRGQKYEFKIRPFAGKNYGPDSNIKHLRIPEEVPNIAPQNINVTAVEGGNGTIVVSW 330 Query: 753 SPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT-SLIMTNLTSGVSYSVQIA 811 PP + + I GY V W N++ + V + T SL + L SG+ Y VQ+A Sbjct: 331 EPPPKNIHSSNIKGYKV---WCF--ENETHPKADWIVDEETKSLEIPMLASGIKYQVQVA 385 Query: 812 AETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETWFYFLIGAIVLF 871 A G+G S Y IDS V + + E+ + V F +G + Sbjct: 386 AINDAGIGMPSIPKYIMIDSPEV--KEVKDENIYFELIL---QVVRHPAFIGTVGTVAWI 440 Query: 872 KIIVIAGIIYVRKYNIFAKK--SALPNI---YDSNGTSLVTQMNIKAAVSLSH--PLTSC 924 ++V A + R ++ K S L N + S T + +M+I + LSH SC Sbjct: 441 LLMVAAVYVCQRHSKRYSTKQHSILGNSLYRFASEDTIIKHRMDISDSPWLSHTWKSASC 500 Query: 925 YN--KNTVTKTESLLWMENQ 942 +T++ LLW E + Sbjct: 501 SRNYSSTISMNSQLLWSETK 520 Score = 63.3 bits (147), Expect = 4e-08 Identities = 45/156 (28%), Positives = 69/156 (44%), Gaps = 11/156 (7%) Query: 134 GSPEPNVYWKKNGQTLLFDGDSR-----MHLVDGGNLVI---QDARQTDAGRYQCIARNA 185 G+P+P + W +NG+ + D + + L +G Q ++D G Y C+ARN Sbjct: 31 GNPQPTIEWYRNGEHVETSTDDKTQRSYVQLPEGPLFFFSLNQRKGKSDEGIYTCVARNH 90 Query: 186 AGTRESAIATLKIH-IKPYLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGN 243 GT S A+L + ++ P D V G + +C G P P+V W++ N Sbjct: 91 LGTAFSRNASLYVAALRDDFRLNPSDAVVAVGKQLEIECLPPKGHPEPNVTWKKDGIPIN 150 Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279 R + G L + + D G YSC A N VG Sbjct: 151 HNNSRYTI-SAGKLFIGKALKTDSGLYSCLASNQVG 185 Score = 60.1 bits (139), Expect = 4e-07 Identities = 45/188 (23%), Positives = 74/188 (39%), Gaps = 10/188 (5%) Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 PP I P+ + V+ A C A G P+PT+ W G + + Sbjct: 5 PPRIIEHPSDLFVKKDKPATLYCRAEGNPQPTIEWYRNGEHVETSTDDKTQRSYVQLPEG 64 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK---LTVTSDDDRPPPIITNGPSNQT 408 + ++N C A N+ G++F R + DD R PS+ Sbjct: 65 PLFFFSLNQRKGKSDEGIYTCVARNHLGTAFSRNASLYVAALRDDFRL------NPSDAV 118 Query: 409 LPIKSMAVFPCTAICT-PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467 + + C PEP + W +G + N+ R + G L + K+DSG Y+C Sbjct: 119 VAVGKQLEIECLPPKGHPEPNVTWKKDGIPINHNNSRYTISAGKLFIGKALKTDSGLYSC 178 Query: 468 VASSRHGK 475 +AS++ G+ Sbjct: 179 LASNQVGE 186 >UniRef50_Q7Z5N4 Cluster: Protein sidekick-1 precursor; n=62; Euteleostomi|Rep: Protein sidekick-1 precursor - Homo sapiens (Human) Length = 2213 Score = 165 bits (401), Expect = 6e-39 Identities = 214/823 (26%), Positives = 320/823 (38%), Gaps = 89/823 (10%) Query: 22 TVARHQPATLNCRAGGS-PSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80 TV++ + A LN S P P + W++ G ++ +I L L T SDA Sbjct: 201 TVSQGRAAILNLLPITSYPRPQVTWFREGHKIIPSNRIAITLENQLVILATTT----SDA 256 Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLE--------PESKQS--AQGDTVVLECL 130 G Y+ +A N + +H+++ R+ E P +S A LEC+ Sbjct: 257 GAYYVQAVNEKNGENKTSPFIHLSIARDVGTPETMAPTIVVPPGNRSVVAGSSETTLECI 316 Query: 131 -PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189 R + +V WK+NG + S +H G +L I + D G Y C A Sbjct: 317 ASARPVEDLSVTWKRNGVRI----TSGLHSF-GRHLTISNPTSADTGPYVCEAALPGSAF 371 Query: 190 ESAIATLKIHI--KPYLITGPED-VVAQTGSSVTFQCRVGGDPLPDVLWRRSA-GGGNMP 245 E A AT + I PY PE + A+ +V C+ G PLP + W + A + Sbjct: 372 EPARATAFLFIIEPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQ 431 Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLSPNSVNV 304 R KVL G LR+ + D G + C A N G + YL V + P P V Sbjct: 432 NPRYKVLASGGLRIQKLRPEDSGIFQCFASNEGGEIQTHTYLDVTNIAPVFTQRPVDTTV 491 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 G A C +G P+P + W E + I+ G R G+ + + D Sbjct: 492 TDGMTAILRCEVSGAPKPAITWKRENH--ILASGSVRIPRFMLLESGGLQIAPVFIQDAG 549 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424 + C A N GS LTV + I + P + + + A C A Sbjct: 550 N----YTCYAANTEGSLNASATLTVWNRTS-----IVHPPEDHVVIKGTTATLHCGATHD 600 Query: 425 PEPII--AWYFEGEALI--QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480 P + W + AL R V DG+L++ D G Y+C S G Sbjct: 601 PRVSLRYVWKKDNVALTPSSTSRIVVEKDGSLLISQTWSGDIGDYSCEIVSEGGNDSRMA 660 Query: 481 AL-LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQ 539 L +++ P +P +L P +H +V LSW + G+S IL Y Sbjct: 661 RLEVIELPHSP----------QNLLVSPNSSHSH-----AVVLSWVRPFD-GNSPILYYI 704 Query: 540 VEVFSRETLSGNNTPRNSRGWVVIARRV--HQTHYVVKSLIPGITYMFIVRTENSHGLSG 597 VE LS N++P W V V T V L P TY F V N G Sbjct: 705 VE------LSENSSP-----WKVHLSNVGPEMTGVTVSGLTPARTYQFRVCAVNEVGRGQ 753 Query: 598 PSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILN 657 S + + + ++ S V++ R N I+ + P E + Sbjct: 754 YSAETSRLMLPEEPPSAPPKNIVASG---RTN---QSIMVQWQPPP----------ETEH 797 Query: 658 FYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGK 717 L G + +R L + EY+ + I S +V+ +T L +T+YE + + G Sbjct: 798 NGVLRGYILRYR-LAGLPGEYQQRNIT-SPEVNYCLVTDLIIWTQYEIQVAAYNGAGLGV 855 Query: 718 PSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVP 777 S + TL VP PP N++ +N+TT+ W+PP Q NGI GY ++ D P Sbjct: 856 FSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADAP 915 Query: 778 ANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGP 820 ++V I H +TNL +Y + T G GP Sbjct: 916 EAVTVVTIAPDFHGVHHGHITNLKKFTAYFTSVLCFTTPGDGP 958 Score = 124 bits (300), Expect = 1e-26 Identities = 94/322 (29%), Positives = 142/322 (44%), Gaps = 16/322 (4%) Query: 11 APYIIEQPLDVTV-ARHQPATLNCRAGGSPSP--AIRWYKGGVLVVSDTHRSILPAGGLF 67 AP I+ P + +V A TL C A P ++ W + GV + S H L Sbjct: 292 APTIVVPPGNRSVVAGSSETTLECIASARPVEDLSVTWKRNGVRITSGLHSF---GRHLT 348 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ-GDTV 125 T +D G Y CEA AT + ++ F EPES+ SA+ +TV Sbjct: 349 ISNPTS----ADTGPYVCEAALPGSAFEPARATAFLFIIEPPYFTAEPESRISAEVEETV 404 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 + C G P P + W K+ ++ + R ++ G L IQ R D+G +QC A N Sbjct: 405 DIGC-QAMGVPLPTLQWYKDAISISRLQNPRYKVLASGGLRIQKLRPEDSGIFQCFASNE 463 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS---AGGG 242 G ++ +I P P D G + +C V G P P + W+R G Sbjct: 464 GGEIQTHTYLDVTNIAPVFTQRPVDTTVTDGMTAILRCEVSGAPKPAITWKRENHILASG 523 Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302 ++ + R +L+ G L++ V + D G Y+C A N+ G+++AS LTV++ SI P Sbjct: 524 SVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAANTEGSLNASATLTVWNRTSIVHPPEDH 583 Query: 303 NVESGNVARFTCTATGRPEPTM 324 V G A C AT P ++ Sbjct: 584 VVIKGTTATLHCGATHDPRVSL 605 Score = 118 bits (285), Expect = 7e-25 Identities = 110/421 (26%), Positives = 185/421 (43%), Gaps = 34/421 (8%) Query: 10 EAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGL 66 E PY +P ++ + + C+A G P P ++WYK + + + + +L +GGL Sbjct: 384 EPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQNPRYKVLASGGL 443 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126 + D+G++ C A+N G ++ + L V + F P G T + Sbjct: 444 RIQKLRP----EDSGIFQCFASNEGGEIQT-HTYLDVTNIAPVFTQRPVDTTVTDGMTAI 498 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH---LVDGGNLVIQDARQTDAGRYQCIAR 183 L C G+P+P + WK+ +L G R+ L++ G L I DAG Y C A Sbjct: 499 LRC-EVSGAPKPAITWKRENH-ILASGSVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAA 556 Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV--LWRR-SAG 240 N G+ +A ATL + + ++ PED V G++ T C DP + +W++ + Sbjct: 557 NTEGSL-NASATLTVWNRTSIVHPPEDHVVIKGTTATLHCGATHDPRVSLRYVWKKDNVA 615 Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV----YDPPSIN 296 R+ V DGSL + D G+YSCE + G S L V + P ++ Sbjct: 616 LTPSSTSRIVVEKDGSLLISQTWSGDIGDYSCEIVSEGGNDSRMARLEVIELPHSPQNLL 675 Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356 +SPNS + V + G P +++ VE + S K H + V +T + Sbjct: 676 VSPNSSH-SHAVVLSWVRPFDGN-SPILYYIVE-----LSENSSPWKVHLSNVGPEMTGV 728 Query: 357 TINDTDKNDSRNTIVCSAVNYAGS---SFVRGKLTVTSDDDRPPP--IITNGPSNQTLPI 411 T++ + VC AVN G S +L + + PP I+ +G +NQ++ + Sbjct: 729 TVSGLTPARTYQFRVC-AVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIMV 787 Query: 412 K 412 + Sbjct: 788 Q 788 Score = 101 bits (243), Expect = 9e-20 Identities = 108/427 (25%), Positives = 162/427 (37%), Gaps = 40/427 (9%) Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138 DAG Y C N G R + + VA + F + K +QG +L LP P P Sbjct: 163 DAGFYRCVVRNRMGALLQRKSEVQVAYMGS-FMDTDQRKTVSQGRAAILNLLPITSYPRP 221 Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY--QCIARNAAGTRESAIATL 196 V W + G ++ +R+ + LVI +DAG Y Q + + S L Sbjct: 222 QVTWFREGHKII--PSNRIAITLENQLVILATTTSDAGAYYVQAVNEKNGENKTSPFIHL 279 Query: 197 KIH--------IKPYLITGPEDVVAQTGSS-VTFQCRVGGDPLPD--VLWRRSAGGGNMP 245 I + P ++ P + GSS T +C P+ D V W+R+ G + Sbjct: 280 SIARDVGTPETMAPTIVVPPGNRSVVAGSSETTLECIASARPVEDLSVTWKRN--GVRIT 337 Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAE---NSVGAVSASGYLTVYDPPSINLSPNS- 301 G L + N AD G Y CEA ++ A+ +L + +PP P S Sbjct: 338 SGLHSF--GRHLTISNPTSADTGPYVCEAALPGSAFEPARATAFLFIIEPPYFTAEPESR 395 Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361 ++ E C A G P PT+ W + I + +Y A G+ + + Sbjct: 396 ISAEVEETVDIGCQAMGVPLPTLQWYKDA---ISISRLQNPRYKVLAS-GGLRIQKLRPE 451 Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421 D C A N G L VT+ P+ T P + T+ A+ C Sbjct: 452 DSG----IFQCFASNEGGEIQTHTYLDVTNI----APVFTQRPVDTTVTDGMTAILRCEV 503 Query: 422 ICTPEPIIAWYFEGEAL----IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477 P+P I W E L ++ R + G L + + D+G YTC A++ G Sbjct: 504 SGAPKPAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAANTEGSLN 563 Query: 478 WSGALLV 484 S L V Sbjct: 564 ASATLTV 570 Score = 74.5 bits (175), Expect = 2e-11 Identities = 87/382 (22%), Positives = 155/382 (40%), Gaps = 37/382 (9%) Query: 110 FRLEPESKQ-SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ 168 F+ EP Q +G+ +VL CL P + + + + + + + +I Sbjct: 106 FKTEPGLPQIHLEGNRLVLTCLAEGSWPLEFKWMRDDSELTTYSSEYKY--------IIP 157 Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGG 227 ++ DAG Y+C+ RN G + +++ ++ ++ T V+Q +++ + Sbjct: 158 SLQKLDAGFYRCVVRNRMGALLQRKSEVQVAYMGSFMDTDQRKTVSQGRAAILNLLPITS 217 Query: 228 DPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSV-GAVSASGY 286 P P V W R G +P R+ + + L + +D G Y +A N G S + Sbjct: 218 YPRPQVTWFRE-GHKIIPSNRIAITLENQLVILATTTSDAGAYYVQAVNEKNGENKTSPF 276 Query: 287 L------TVYDP----PSINLSPNSVNVESGNV-ARFTCTATGRPEPTMFWSVEGNRTII 335 + V P P+I + P + +V +G+ C A+ RP + + + N I Sbjct: 277 IHLSIARDVGTPETMAPTIVVPPGNRSVVAGSSETTLECIASARPVEDLSVTWKRNGVRI 336 Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395 G+ H LTI++ D+ VC A GS+F + T Sbjct: 337 TSGLHSFGRH----------LTISNPTSADT-GPYVCEAA-LPGSAFEPARATAFLFIIE 384 Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL--IQNHRRNVTNDGTLV 453 PP S + ++ C A+ P P + WY + ++ +QN R V G L Sbjct: 385 PPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQNPRYKVLASGGLR 444 Query: 454 LKDLDKSDSGTYTCVASSRHGK 475 ++ L DSG + C AS+ G+ Sbjct: 445 IQKLRPEDSGIFQCFASNEGGE 466 Score = 66.5 bits (155), Expect = 4e-09 Identities = 53/187 (28%), Positives = 86/187 (45%), Gaps = 10/187 (5%) Query: 637 ELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNIT-IEYEMKT-ILHSNDVSGFEI 694 E + A + S I L W + GL + ++ L ++ E ++ I+ N + Sbjct: 1281 ENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFRAKDLDPEPRSHIVRGNHTQSALL 1340 Query: 695 TSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQ-TLDDVPDGPPINIEMFILNTTTVHLKWS 753 LRK+ YE ++ F + G PS + + T DD P GPP+ + + T+V + W Sbjct: 1341 AGLRKFVLYELQVLAFTRIGNGVPSTPLILERTKDDAP-GPPVRLVFPEVRLTSVRIVWQ 1399 Query: 754 PPELQLQNGIITGYNVVVNWL-DVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAA 812 PPE NGII GY + P + V + TV Q T+ T+L +Y +++A Sbjct: 1400 PPE--EPNGIILGYQIAYRLASSSPHTFTTVEVGATVRQFTA---TDLAPESAYIFRLSA 1454 Query: 813 ETIIGLG 819 +T G G Sbjct: 1455 KTRQGWG 1461 Score = 58.4 bits (135), Expect = 1e-06 Identities = 49/187 (26%), Positives = 93/187 (49%), Gaps = 14/187 (7%) Query: 639 IEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILH-SNDVSGFE---I 694 ++ ++S TI+ +W ++ G+ ++ L E T++ + D G I Sbjct: 876 VQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADAPEAVTVVTIAPDFHGVHHGHI 935 Query: 695 TSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSP 754 T+L+K+T Y ++ F +G PS ++ T +D P G ++ + T++ + W Sbjct: 936 TNLKKFTAYFTSVLCFTTPGDGPPSTPQLVWTQEDKP-GAVGHLSFTEILDTSLKVSWQE 994 Query: 755 PELQLQNGIITGYNVVVNWLDVPANKSMV--AINTTVHQATSLIMTNLTSGVSYSVQIAA 812 P L+ +NGIITGY ++W N S + +N+T H+ + L+S +Y++ +AA Sbjct: 995 P-LE-KNGIITGYQ--ISWEVYGRNDSRLTHTLNSTTHEYK---IQGLSSLTTYTIDVAA 1047 Query: 813 ETIIGLG 819 T +G G Sbjct: 1048 VTAVGTG 1054 Score = 58.4 bits (135), Expect = 1e-06 Identities = 83/336 (24%), Positives = 140/336 (41%), Gaps = 39/336 (11%) Query: 504 PGPPTKPITHN--VTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV 561 P PP + + VT S+ L W + G+S I + ++V RE PR W Sbjct: 1477 PAPPRELLVPQAEVTARSLRLQWVPGSD-GASPIRYFTMQV--REL------PRGE--WQ 1525 Query: 562 VIARRV-HQ-THYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTG 619 + + H+ T VV L P +Y ++ N G S S +++VT D E G Sbjct: 1526 TYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPG--EPPG 1583 Query: 620 VSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLE-----GLFIYFRPLDN- 673 ++T + + + LI+ P +++ + + YY E G + L N Sbjct: 1584 SVSATPHTTSSV------LIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNP 1637 Query: 674 ------ITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTL 727 +T + KT+ S+ + E+T L+KY +YE + Y P+++ V + Sbjct: 1638 IALHAELTAQSSFKTVNSSSTSTMCELTHLKKYRRYEVIMTA-YNIIGESPASAPVEVFV 1696 Query: 728 DDV-PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN 786 + P P N+++ L + + + W PP + QNG I GY + W + + + Sbjct: 1697 GEAAPAMAPQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYY-W-EADSQNETEKMK 1754 Query: 787 TTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFS 822 + + NLTS Y V I+A G GP S Sbjct: 1755 VLFLPEPVVRLKNLTSHTKYLVSISAFNAAGDGPKS 1790 Score = 53.2 bits (122), Expect = 4e-05 Identities = 44/182 (24%), Positives = 81/182 (44%), Gaps = 10/182 (5%) Query: 639 IEATPIDSKTIKLMWEI----LNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEI 694 ++ TP+ + +++ W+ ++G IY+ D+ +MK + V + Sbjct: 1708 VQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPV--VRL 1765 Query: 695 TSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSP 754 +L +TKY + F +G S+ + +T P G P + + +TT+++ W Sbjct: 1766 KNLTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAP-GAPSFLAFSEITSTTLNVSWGE 1824 Query: 755 PELQLQNGIITGYNVVVNWL-DVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAE 813 P NGI+ GY VV L V +V + + L + +LT GV+Y ++ A Sbjct: 1825 PAAA--NGILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQAR 1882 Query: 814 TI 815 TI Sbjct: 1883 TI 1884 Score = 51.6 bits (118), Expect = 1e-04 Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 4/129 (3%) Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751 F I L ++ +YE + F G S +T + VP P N+ +++T + L Sbjct: 1237 FTIEELEEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILLT 1296 Query: 752 WSPPELQLQNGIITGYNVVVNWLDV-PANKSMVAINTTVHQATSLIMTNLTSGVSYSVQI 810 W+ Q QNG+I GY ++ D+ P +S + + S ++ L V Y +Q+ Sbjct: 1297 WTSVPEQDQNGLILGYKILFRAKDLDPEPRSHIVRG---NHTQSALLAGLRKFVLYELQV 1353 Query: 811 AAETIIGLG 819 A T IG G Sbjct: 1354 LAFTRIGNG 1362 Score = 50.0 bits (114), Expect = 4e-04 Identities = 34/139 (24%), Positives = 60/139 (43%), Gaps = 3/139 (2%) Query: 688 DVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTL-DDVPDGPPINIEMFILNTT 746 +++G ++ L Y+F + + G+ S L ++ P PP NI Sbjct: 724 EMTGVTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQ 783 Query: 747 TVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSY 806 ++ ++W PP NG++ GY + +P N T + ++T+L Y Sbjct: 784 SIMVQWQPPPETEHNGVLRGYILRYRLAGLPGEYQQ--RNITSPEVNYCLVTDLIIWTQY 841 Query: 807 SVQIAAETIIGLGPFSQKV 825 +Q+AA GLG FS+ V Sbjct: 842 EIQVAAYNGAGLGVFSRAV 860 Score = 48.0 bits (109), Expect = 0.002 Identities = 37/140 (26%), Positives = 57/140 (40%), Gaps = 3/140 (2%) Query: 688 DVSGFEITSLRKYTKYEFFL--IPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNT 745 D EI +L YT Y F + + PS SRV QTL PD P ++ + + Sbjct: 1129 DAQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPS-SRVIQTLQAPPDVAPTSVTVRTASE 1187 Query: 746 TTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVS 805 T++ L+W P NG + + S VA + + L + Sbjct: 1188 TSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWME 1247 Query: 806 YSVQIAAETIIGLGPFSQKV 825 Y +Q+ A +G GP+S+ V Sbjct: 1248 YELQMQAFNAVGAGPWSEVV 1267 Score = 46.4 bits (105), Expect = 0.005 Identities = 73/352 (20%), Positives = 133/352 (37%), Gaps = 32/352 (9%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 PGPP + + V TSV + W Q + + ILGYQ+ R S +T V + Sbjct: 1378 PGPPVRLVFPEVRLTSVRIVW-QPPEEPNGIILGYQIAY--RLASSSPHTFTT----VEV 1430 Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNS 623 V Q + L P Y+F + + G P E T ++ Sbjct: 1431 GATVRQ--FTATDLAPESAYIFRLSAKTRQGWGEPL----------------EATVITTE 1472 Query: 624 TEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTI 683 R + +V E T +++++L W + + + + E++ + Sbjct: 1473 KRERPAPPRELLVPQAEVT---ARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQTYSS 1529 Query: 684 LHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGK-PSNSRVAQTLDDVPDGPPINIEMFI 742 S++ + + LR +T Y+ L + S + TL DVP PP ++ Sbjct: 1530 SISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATP 1589 Query: 743 LNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTS 802 T++V ++W PP + NG++ GY + L+ A A T+ +L LT+ Sbjct: 1590 HTTSSVLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEA--KTLKNPIAL-HAELTA 1646 Query: 803 GVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGD 854 S+ ++ T K Y + +++ P + V + G+ Sbjct: 1647 QSSFKTVNSSSTSTMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGE 1698 >UniRef50_Q8TD84 Cluster: Down syndrome cell adhesion molecule-like protein 1 precursor; n=63; Euteleostomi|Rep: Down syndrome cell adhesion molecule-like protein 1 precursor - Homo sapiens (Human) Length = 2053 Score = 164 bits (399), Expect = 1e-38 Identities = 207/832 (24%), Positives = 340/832 (40%), Gaps = 74/832 (8%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I ++T + +NCR G P +I+WYK +L+ D HR ++ G L+ Sbjct: 505 PPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLL-PDNHRQVVFENGT--LKL 561 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131 T + D G Y C + S++ +HVAV E ++ G + + C+ Sbjct: 562 TDVQKGMDEGEYLCSVLIQPQLSISQS--VHVAVKVPPLIQPFEFPPASIGQLLYIPCVV 619 Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRE 190 G + W+K+GQ ++ + + +L I G Y CIA NAA T Sbjct: 620 SSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAAT-V 678 Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN------M 244 S L + + P + P + G + C V G P P V+W+ + G GN + Sbjct: 679 SRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPV 738 Query: 245 PL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSV 302 PL GR+++L + SL + +V+ D G Y C+A N VG +S S +LTV P I PN+ Sbjct: 739 PLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSHPNTT 798 Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG----VTVLTI 358 G+ CTA G + W E T+I P R +A A D V+ L + Sbjct: 799 IAIKGHAKELNCTARGERPIIIRW--EKGDTVIDP--DRVMRYAIATKDNGDEVVSTLKL 854 Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418 D+ DS C A+N G +LTV D PP + +++ ++ F Sbjct: 855 KPADRGDS-VFFSCHAINSYGEDRGLIQLTVQEPPD-PPELEIREVKARSMNLRWTQRFD 912 Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGK 475 +I T I + RN++ N +V DL + + + ++ G+ Sbjct: 913 GNSIITGFDIEYKNKSDSWDFKQSTRNISPTINQANIV--DLHPASVYSIRMYSFNKIGR 970 Query: 476 YVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK-IGSSS 534 S L + + + ++ GPP VT S+ ++W K + + Sbjct: 971 SEPSKELTI------------STEEAAPDGPPMDVTLQPVTSQSIQVTWKAPKKELQNGV 1018 Query: 535 ILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHG 594 I GYQ+ RE G+N V + Y + +L Y +V+ N G Sbjct: 1019 IRGYQIGY--RENSPGSN---GQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAG 1073 Query: 595 LSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWE 654 +GPS + T +D S R +T + + + P S Sbjct: 1074 -TGPSSSEINATTLEDVPS-------QPPENVRALSITSDVAVISWSEPPRS-------- 1117 Query: 655 ILNFYYLEGLFIYFRPLDNITIEY-EMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKK 713 LN L+G + F L + E+ EM+ I + + E+ + K+T Y ++ + + Sbjct: 1118 TLN-GVLKGYRVIFWSL-YVDGEWGEMQNITTTRE--RVELRGMEKFTNYSVQVLAYTQA 1173 Query: 714 FEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNW 773 +G S+ QT +DVP GPP I+ + ++V + W PP NG+I Y + + Sbjct: 1174 GDGVRSSVLYIQTKEDVP-GPPAGIKAVPSSASSVVVSWLPP--TKPNGVIRKYTIFCS- 1229 Query: 774 LDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825 + + + T + + +L G Y + +AA T G G S+KV Sbjct: 1230 -SPGSGQPAPSEYETSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNSSEKV 1280 Score = 141 bits (341), Expect = 1e-31 Identities = 135/524 (25%), Positives = 224/524 (42%), Gaps = 47/524 (8%) Query: 9 GEAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAGGL 66 G + Y + L VT + + C A GSPS A+RWY G + H + A G Sbjct: 22 GTSLYFVNDSLQQVTFSSSVGVVVPCPAAGSPSAALRWYLATGDDIYDVPHIRHVHANGT 81 Query: 67 FFL-----RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121 L A + +H + Y+C A N+ G RS N + AV RE + + E ++S + Sbjct: 82 LQLYPFSPSAFNSFIHDND--YFCTAENAAGKIRSPNIRVK-AVFREPYTVRVEDQRSMR 138 Query: 122 GDTVVLECLPPRGSPE--PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRY 178 G+ V +CL P E V W+K+ +++ + R + G L I D ++ DA Y Sbjct: 139 GNVAVFKCLIPSSVQEYVSVVSWEKDTVSII--PEHRFFITYHGGLYISDVQKEDALSTY 196 Query: 179 QCIARN--AAGTRESAIATLKI----HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232 +CI ++ + TR+S A L + P ++ G G +V C G P+P Sbjct: 197 RCITKHKYSGETRQSNGARLSVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPA 256 Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292 + W + G +P L + ++ D G Y CE N+ G+ A+G L V DP Sbjct: 257 IRWLKD--GRPLPADSRWTKRITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVIDP 314 Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352 + L+P + G+ +C TG PE T+ W N ++ P D+ + Sbjct: 315 LHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRW--YRNTELVLP----DEAISIRGLSN 368 Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412 T+L I K+ S C A A ++ + + +D P I+++ P + Sbjct: 369 ETLL-ITSAQKSHS-GAYQCFATRKAQTA---QDFAIIALEDGTPRIVSSFSEKVVNPGE 423 Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQ--NHRRN--VTNDGTLV----LKDLDKSDSGT 464 ++ C A P P + W + E +++ +HR N +DGT + + D G Sbjct: 424 QFSLM-CAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGV 482 Query: 465 YTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPT 508 Y C A + G + + V P P+I R +++++ G T Sbjct: 483 YRCTARNLVGSAEYQARINVRGP--PSIRAMR--NITAVAGRDT 522 Score = 132 bits (319), Expect = 6e-29 Identities = 207/850 (24%), Positives = 335/850 (39%), Gaps = 109/850 (12%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-THRS---ILPAGGLF 67 P I+ + V + +L C A G+P P + W +V D +HR+ + G Sbjct: 408 PRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTI 467 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127 G D GVY C A N G+A + A ++V R A DT++ Sbjct: 468 SHMNVTGPQIRDGGVYRCTARNLVGSAEYQ-ARINVRG-PPSIRAMRNITAVAGRDTLI- 524 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ-TDAGRYQC--IARN 184 C G P ++ W K+ LL + R + + G L + D ++ D G Y C + + Sbjct: 525 NCRVI-GYPYYSIKWYKDA--LLLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQP 581 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRRSA---- 239 +S +K+ P LI E A G + C V +P + WR+ Sbjct: 582 QLSISQSVHVAVKV---PPLIQPFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVII 638 Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299 G + + + + SL++ +V L G Y+C A N+ VS L V PP + P Sbjct: 639 SGSGVTIESKEFMS--SLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPPRFVVQP 696 Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWS-VEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358 N+ + G C+ G P P + W +G+ + +YH + + +L Sbjct: 697 NNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSG-------NPQQYHPVPLTGRIQILPN 749 Query: 359 NDT----DKNDSRNTIVCSAVNYAGSSFVRGK-LTVTSDDDRPPPIITNGPSNQTLPIKS 413 + + +C A N G+ + LTV + P +IT+ P N T+ IK Sbjct: 750 SSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTV-----KIPAMITSHP-NTTIAIKG 803 Query: 414 MA-VFPCTAICTPEPIIAWYFEGEALIQNHR----RNVTND------GTLVLKDLDKSDS 462 A CTA PII + +G+ +I R T D TL LK D+ DS Sbjct: 804 HAKELNCTA-RGERPIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDS 862 Query: 463 GTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTL 522 ++C A + +G+ L V P P PP I V S+ L Sbjct: 863 VFFSCHAINSYGEDRGLIQLTVQEP----------------PDPPELEI-REVKARSMNL 905 Query: 523 SWSQNNKIGSSSILGYQVEVFSR-ETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGI 581 W+Q G+S I G+ +E ++ ++ + RN I+ ++Q + V L P Sbjct: 906 RWTQRFD-GNSIITGFDIEYKNKSDSWDFKQSTRN------ISPTINQANIV--DLHPAS 956 Query: 582 TYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEA 641 Y + + N G S P S +T+ STE D + Sbjct: 957 VYSIRMYSFNKIGRSEP---SKELTI---------------STE---EAAPDGPPMDVTL 995 Query: 642 TPIDSKTIKLMWEI----LNFYYLEGLFIYFRP-LDNITIEYEMKTILHSNDVSGFEITS 696 P+ S++I++ W+ L + G I +R +Y + + + D + + + Sbjct: 996 QPVTSQSIQVTWKAPKKELQNGVIRGYQIGYRENSPGSNGQYSIVEMKATGDSEVYTLDN 1055 Query: 697 LRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPE 756 L+K+ +Y + F + G S+ A TL+DVP PP N+ + + + WS P Sbjct: 1056 LKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPENVRALSITSDVAVISWSEPP 1115 Query: 757 LQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETII 816 NG++ GY V+ L V + TT + L + +YSVQ+ A T Sbjct: 1116 RSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTTRERVEL--RGMEKFTNYSVQVLAYTQA 1173 Query: 817 GLGPFSQKVY 826 G G S +Y Sbjct: 1174 GDGVRSSVLY 1183 Score = 118 bits (285), Expect = 7e-25 Identities = 156/610 (25%), Positives = 242/610 (39%), Gaps = 41/610 (6%) Query: 43 IRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG--TARSRNAT 100 + W K V ++ + I GGL+ + + Y C + Y T +S A Sbjct: 159 VSWEKDTVSIIPEHRFFITYHGGLYI---SDVQKEDALSTYRCITKHKYSGETRQSNGAR 215 Query: 101 LHVAVLREEFRLEPESKQSAQ---GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM 157 L V E + S + G TV L C G P P + W K+G+ L DSR Sbjct: 216 LSVTDPAESIPTILDGFHSQEVWAGHTVELPCTAS-GYPIPAIRWLKDGRPL--PADSRW 272 Query: 158 HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT-GPEDVVAQTG 216 G L I D R D+G Y C N G+ E A L + I P +T P+ + G Sbjct: 273 TKRITG-LTISDLRTEDSGTYICEVTNTFGSAE-ATGILMV-IDPLHVTLTPKKLKTGIG 329 Query: 217 SSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDGSLRLDNVILADEGEYSCEA 274 S+V C + G P + W R+ +P + + L + +L + + + G Y C A Sbjct: 330 STVILSCALTGSPEFTIRWYRNTELV-LPDEAISIRGLSNETLLITSAQKSHSGAYQCFA 388 Query: 275 ENSVGAVSASGYLTVYD-PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRT 333 + + D P I S + V G C A G P PT+ W+++ + Sbjct: 389 TRKAQTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALD-DEP 447 Query: 334 IIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV-CSAVNYAGSSFVRGKLTVTSD 392 I+ G R + + DG T+ +N T + C+A N GS+ + ++ V Sbjct: 448 IVRDGSHRTNQYTMS--DGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINV--- 502 Query: 393 DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTL 452 R PP I N T + C I P I WY + L NHR+ V +GTL Sbjct: 503 --RGPPSI-RAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDNHRQVVFENGTL 559 Query: 453 VLKDLDKS-DSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI 511 L D+ K D G Y C + + S ++ V + P I F +S+ P Sbjct: 560 KLTDVQKGMDEGEYLCSVLIQPQLSI-SQSVHVAVKVPPLIQPFEFPP-ASIGQLLYIPC 617 Query: 512 THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLS----GNNTPRNSRGWVVIARRV 567 + D + ++W K G I G V + S+E +S + + +++ + IA Sbjct: 618 VVSSGDMPIRITW---RKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNA 674 Query: 568 HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD-SVTVGDDSNSLWE-GTGVSNSTE 625 T + LI + F+V+ N G+ G + V + SV +W+ G N + Sbjct: 675 AATVSRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQ 734 Query: 626 YRNNILTDHI 635 Y LT I Sbjct: 735 YHPVPLTGRI 744 Score = 92.3 bits (219), Expect = 7e-17 Identities = 119/466 (25%), Positives = 189/466 (40%), Gaps = 47/466 (10%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 L+C GSP IRWY+ LV+ D SI L + + HS G Y C AT Sbjct: 334 LSCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHS--GAYQCFATRK 391 Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150 TA+ A + + K G+ L C +G+P P V W + + ++ Sbjct: 392 AQTAQDF-AIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAA-KGAPPPTVTWALDDEPIV 449 Query: 151 FDGDSRMH---LVDG---GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK-PY 203 DG R + + DG ++ + + D G Y+C ARN G+ E +I+++ P Sbjct: 450 RDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQA---RINVRGPP 506 Query: 204 LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNV 262 I ++ A G CRV G P + W + A +P R V ++G+L+L +V Sbjct: 507 SIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDAL--LLPDNHRQVVFENGTLKLTDV 564 Query: 263 ILA-DEGEYSCEAENSVG-AVSASGYLTVYDPPSIN---LSPNSVNVESGNVARFTCTAT 317 DEGEY C ++S S ++ V PP I P S+ G + C + Sbjct: 565 QKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFEFPPASI----GQLLYIPCVVS 620 Query: 318 GRPEPTMF-WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376 P W +G I G++ + + ++ L I+ + N C A N Sbjct: 621 SGDMPIRITWRKDGQVIISGSGVTIESK------EFMSSLQISSVSLKHNGN-YTCIASN 673 Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-YFEG 435 A + +L V R PP P+NQ V C+ P P + W + +G Sbjct: 674 AAATVSRERQLIV-----RVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKG 728 Query: 436 EALIQNH-------RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 Q + R + + +L+++ + + D G Y C AS+ G Sbjct: 729 SGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVG 774 Score = 61.3 bits (142), Expect = 2e-07 Identities = 43/186 (23%), Positives = 79/186 (42%), Gaps = 8/186 (4%) Query: 677 EYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPI 736 +++ T S ++ I L + Y + F K +PS T + PDGPP+ Sbjct: 932 DFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPM 991 Query: 737 NIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLI 796 ++ + + + ++ + W P+ +LQNG+I GY + + P + +I S + Sbjct: 992 DVTLQPVTSQSIQVTWKAPKKELQNGVIRGYQIGYR-ENSPGSNGQYSIVEMKATGDSEV 1050 Query: 797 MT--NLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGD 854 T NL Y V + A G GP S ++ + + D+ S+ P N + D Sbjct: 1051 YTLDNLKKFAQYGVVVQAFNRAGTGPSSSEI-----NATTLEDVPSQPPENVRALSITSD 1105 Query: 855 FVMETW 860 + +W Sbjct: 1106 VAVISW 1111 Score = 51.6 bits (118), Expect = 1e-04 Identities = 63/241 (26%), Positives = 102/241 (42%), Gaps = 35/241 (14%) Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432 +AV AG K+T+ P II+ G + T +K + + PC ++ P P + W Sbjct: 1266 AAVTSAGRGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRL-PCNSVGDPAPAVKWT 1324 Query: 433 FEGE-----ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 + E + HR TN GTL+L+ + DSG YTC A++ G LLV P Sbjct: 1325 KDSEDSAIPVSMDGHRLIHTN-GTLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVP 1383 Query: 488 INPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRET 547 P P ++ + +S+TL+W + G SSI G+ ++ +S + Sbjct: 1384 ----------------PDQPRLTVS-KTSASSITLTWIPGDN-GGSSIRGFVLQ-YSVD- 1423 Query: 548 LSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607 NS W + + + + SL G Y + +NS G S + ++ T Sbjct: 1424 --------NSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGRISEIIEAKTH 1475 Query: 608 G 608 G Sbjct: 1476 G 1476 Score = 43.2 bits (97), Expect = 0.044 Identities = 31/90 (34%), Positives = 43/90 (47%), Gaps = 9/90 (10%) Query: 8 SGEAPY-IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK----GGVLVVSDTHRSILP 62 +G+AP II VT + L C + G P+PA++W K + V D HR ++ Sbjct: 1285 AGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHR-LIH 1343 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYG 92 G LRA D+G Y C ATN+ G Sbjct: 1344 TNGTLLLRAVKA---EDSGYYTCTATNTGG 1370 Score = 38.7 bits (86), Expect = 0.96 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 3/78 (3%) Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAE 275 V C GDP P V W + + +P+ G + +G+L L V D G Y+C A Sbjct: 1307 VRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTAT 1366 Query: 276 NSVGAVSASGYLTVYDPP 293 N+ G + L V PP Sbjct: 1367 NTGGFDTIIVNLLVQVPP 1384 Score = 37.5 bits (83), Expect = 2.2 Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 10/99 (10%) Query: 134 GSPEPNVYWKKNGQT----LLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189 G P P V W K+ + + DG +H G L+++ + D+G Y C A N G Sbjct: 1315 GDPAPAVKWTKDSEDSAIPVSMDGHRLIHT--NGTLLLRAVKAEDSGYYTCTATNTGGF- 1371 Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228 ++ I L + + P P V++T +S + GD Sbjct: 1372 DTIIVNLLVQVPP---DQPRLTVSKTSASSITLTWIPGD 1407 >UniRef50_UPI0000DB7011 Cluster: PREDICTED: similar to CG33519-PB isoform 1; n=1; Apis mellifera|Rep: PREDICTED: similar to CG33519-PB isoform 1 - Apis mellifera Length = 2794 Score = 164 bits (398), Expect = 1e-38 Identities = 156/619 (25%), Positives = 251/619 (40%), Gaps = 53/619 (8%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG-GLFFLRATHGRVHS 78 DV + +P L + P+P ++W+K G+ + + G+ LR R Sbjct: 898 DVKIVVGEPLKLEAQVVAFPNPEVQWFKNGIPLRQTKEMYFINEPIGIIGLRIDSCRPE- 956 Query: 79 DAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137 DAG Y +NS G T + + R EF + + +G +E + G P Sbjct: 957 DAGTYSMTVSNSLGETTGTAKVEIEEKERRPEFVVNLQPLSVMEGFPAKME-VKVLGKPT 1015 Query: 138 PNVYWKKNGQTLLFDGD--SRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRE---- 190 P + W KNG+ ++ DG + + DG L+I+ A DAG YQ IA N GT Sbjct: 1016 PRLQWFKNGEEIVPDGKRVKAVSMADGSQALIIEKATPEDAGEYQVIAGNTEGTSSCKGT 1075 Query: 191 -SAIATLKIHI---KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 S + L+ + KP + DV + G + G+P+PDV W + G P Sbjct: 1076 ISVVGKLQSDVSEQKPGFVNPMRDVYVEEGQPLNLSVSFVGNPIPDVNWSKD-GAPLQPS 1134 Query: 247 GRVKVLDDGS---LRLDNVILADEGEYSCEAENSVG---AVSASGYLTVYDPPSINLSPN 300 R + DG L ++ D G Y C N +G S + ++ PPS + Sbjct: 1135 DRFTITCDGKKTELEINPCEGKDAGVYECRISNPLGEDSTRSTANVRKIFQPPSFIHAFK 1194 Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360 + A+F +G P P + W V + I+ DKY D L + D Sbjct: 1195 DLQQLPTFDAKFLARVSGVPRPDITWYVN-EKPIV---QDDDKYKIKRDGDACC-LYVKD 1249 Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR----PPPIITNGPSNQTLPIKSMAV 416 +DS C AVN G + LT+ + + PP + + A Sbjct: 1250 CTYDDS-GVYKCRAVNKGGEAECAANLTIVDEIGKIQKFEPPSFLKRIGDCEMYKGMPAK 1308 Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLV---LKDLDKSDSGTYTCVASSRH 473 F PEP W+ G+ + Q R + +G+L+ + ++D+ D+G YT S+ H Sbjct: 1309 FTACVTGIPEPDFEWFHNGDKMWQTDRIRMDQEGSLLRLTINNVDELDAGKYTLKISNPH 1368 Query: 474 GKYVWSGALLVDS-------PINPNIHFFRAADVSSLPGP-PTKPITHNVTDTSVTLSWS 525 G+ + L+ ++ + F S +P P +PI + D +TLSW Sbjct: 1369 GEDSCTADLIYETLEPRAKKSLGDQYADFDKYRKSGIPLPLADRPIISRMMDRHLTLSWK 1428 Query: 526 QNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMF 585 + IGS + YQ+E+ E G+ W + +++L P Y F Sbjct: 1429 PSIPIGSRIPVTYQIEMC--ELPDGD--------WFTARTGIRSCVCDIRNLEPFRDYKF 1478 Query: 586 IVRTENSHGLSGPSPVSDS 604 +R EN +G+S PSP + + Sbjct: 1479 RIRVENKYGISDPSPYAQT 1497 Score = 113 bits (271), Expect = 4e-23 Identities = 123/521 (23%), Positives = 209/521 (40%), Gaps = 36/521 (6%) Query: 34 RAGGSPSPAIRWYKGGVLVVSDTHRSIL---PAGGLFFLRATHGRVHSDAGVYWCEATNS 90 R G P P ++W + + D I+ + + + SD G C A+N Sbjct: 716 RCSGIPRPNLKWLRCNEEIREDDRYKIVIQEDGNNVESVCSITTFCPSDVGKITCRASNI 775 Query: 91 YGTARSRNATLHVAVLREEF-RLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149 YG+A++ + L V ++ F L P+S + +G + L+ GSP P + W K+G+ + Sbjct: 776 YGSAQT-SCDLLVQLITPSFVNLLPKSTEVDEGGCLELKA-KIDGSPMPEISWYKDGEKI 833 Query: 150 LFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGTRES--AIATLKIHIKPYLI 205 + D +R+ ++ G L+I + D G Y+ + N+ G + S A+A KP Sbjct: 834 VPDEHTRIEILPDGTTKLIIDCVQPLDCGAYKLVINNSTGEQSSLCAVAIKPERRKPSFS 893 Query: 206 TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK---VLDDG----SLR 258 EDV G + + +V P P+V W ++ +PL + K +++ LR Sbjct: 894 KSLEDVKIVVGEPLKLEAQVVAFPNPEVQWFKN----GIPLRQTKEMYFINEPIGIIGLR 949 Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDP---PSINLSPNSVNVESGNVARFTCT 315 +D+ D G YS NS+G + + + + + P ++ ++V G A+ Sbjct: 950 IDSCRPEDAGTYSMTVSNSLGETTGTAKVEIEEKERRPEFVVNLQPLSVMEGFPAKMEVK 1009 Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375 G+P P + W G I P R K A ++ DG L I D+ V A Sbjct: 1010 VLGKPTPRLQWFKNGEE--IVPDGKRVK--AVSMADGSQALIIEKATPEDAGEYQVI-AG 1064 Query: 376 NYAGSSFVRGKLTVT----SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431 N G+S +G ++V SD P N + + + + P P + W Sbjct: 1065 NTEGTSSCKGTISVVGKLQSDVSEQKPGFVNPMRDVYVEEGQPLNLSVSFVGNPIPDVNW 1124 Query: 432 YFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPI 488 +G L + R +T DG L + + D+G Y C S+ G+ V Sbjct: 1125 SKDGAPLQPSDRFTITCDGKKTELEINPCEGKDAGVYECRISNPLGEDSTRSTANVRKIF 1184 Query: 489 NPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529 P D+ LP K + ++W N K Sbjct: 1185 QPPSFIHAFKDLQQLPTFDAKFLARVSGVPRPDITWYVNEK 1225 Score = 106 bits (254), Expect = 4e-21 Identities = 131/473 (27%), Positives = 183/473 (38%), Gaps = 44/473 (9%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHR--SILPAGGLFFLRATHGRVHSDAGVYWCEAT 88 L + GSP P I WYK G +V D H ILP G + + D G Y Sbjct: 812 LKAKIDGSPMPEISWYKDGEKIVPDEHTRIEILPDGTTKLIIDCVQPL--DCGAYKLVIN 869 Query: 89 NSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147 NS G S A R+ F E + G+ + LE P P V W KNG Sbjct: 870 NSTGEQSSLCAVAIKPERRKPSFSKSLEDVKIVVGEPLKLEA-QVVAFPNPEVQWFKNGI 928 Query: 148 TLLFDGDSRMHLVDGG----NLVIQDARQTDAGRYQCIARNAAG--TRESAIATLKIHIK 201 L M+ ++ L I R DAG Y N+ G T + + + + Sbjct: 929 PL--RQTKEMYFINEPIGIIGLRIDSCRPEDAGTYSMTVSNSLGETTGTAKVEIEEKERR 986 Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLD--DGS-- 256 P + + + G + +V G P P + W ++ G +P G RVK + DGS Sbjct: 987 PEFVVNLQPLSVMEGFPAKMEVKVLGKPTPRLQWFKN-GEEIVPDGKRVKAVSMADGSQA 1045 Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS---PNSVN------VESG 307 L ++ D GEY A N+ G S G ++V ++S P VN VE G Sbjct: 1046 LIIEKATPEDAGEYQVIAGNTEGTSSCKGTISVVGKLQSDVSEQKPGFVNPMRDVYVEEG 1105 Query: 308 NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG-VTVLTINDTDKNDS 366 + + G P P + WS +G P D++ T DG T L IN + D+ Sbjct: 1106 QPLNLSVSFVGNPIPDVNWSKDG-----APLQPSDRF--TITCDGKKTELEINPCEGKDA 1158 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426 C N G R V +PP I Q LP A F P Sbjct: 1159 -GVYECRISNPLGEDSTRSTANVRK-IFQPPSFIHAFKDLQQLPTFD-AKFLARVSGVPR 1215 Query: 427 PIIAWYFEGEALIQ-NHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGK 475 P I WY + ++Q + + + DG L +KD DSG Y C A ++ G+ Sbjct: 1216 PDITWYVNEKPIVQDDDKYKIKRDGDACCLYVKDCTYDDSGVYKCRAVNKGGE 1268 Score = 93.9 bits (223), Expect = 2e-17 Identities = 94/340 (27%), Positives = 130/340 (38%), Gaps = 28/340 (8%) Query: 17 QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR--SILPAGGLFFLRATHG 74 QPL +V PA + + G P+P ++W+K G +V D R ++ A G L Sbjct: 994 QPL--SVMEGFPAKMEVKVLGKPTPRLQWFKNGEEIVPDGKRVKAVSMADGSQAL-IIEK 1050 Query: 75 RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR- 133 DAG Y A N+ GT+ + V L+ + + + D V E P Sbjct: 1051 ATPEDAGEYQVIAGNTEGTSSCKGTISVVGKLQSDVSEQKPGFVNPMRDVYVEEGQPLNL 1110 Query: 134 -----GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAA 186 G+P P+V W K+G L D DG L I DAG Y+C N Sbjct: 1111 SVSFVGNPIPDVNWSKDGAPLQ-PSDRFTITCDGKKTELEINPCEGKDAGVYECRISNPL 1169 Query: 187 G--TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 G + S KI P I +D+ F RV G P PD+ W + Sbjct: 1170 GEDSTRSTANVRKIFQPPSFIHAFKDLQQLPTFDAKFLARVSGVPRPDITWYVNEKPIVQ 1229 Query: 245 PLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---------P 292 + K+ DG L + + D G Y C A N G + LT+ D P Sbjct: 1230 DDDKYKIKRDGDACCLYVKDCTYDDSGVYKCRAVNKGGEAECAANLTIVDEIGKIQKFEP 1289 Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332 PS + G A+FT TG PEP W G++ Sbjct: 1290 PSFLKRIGDCEMYKGMPAKFTACVTGIPEPDFEWFHNGDK 1329 Score = 89.8 bits (213), Expect = 4e-16 Identities = 123/548 (22%), Positives = 200/548 (36%), Gaps = 46/548 (8%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWY-KGGVLVVSDTHRSILPAGGLFFLR 70 P IE DV VA + P P I WY KG + D+ I + Sbjct: 494 PKFIETLQDVDVANGKSGMFKAMFTADPVPDITWYFKGDEIHSEDSRLKITVDNKPGSDK 553 Query: 71 ATHGRV--------HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122 T V D G Y + N YG A S NA L++ + E L + G Sbjct: 554 LTETTVTLSVPKCSKDDTGEYTLKLKNKYGEAES-NAFLNLLLCPEIQELNDVTTNV--G 610 Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLL------FDGDSRMHLVDGGNLVIQDARQTDAG 176 +++ + + +G+P+P++ W K+G+ L F+ D R + LVI++ D G Sbjct: 611 ESLAWQAII-KGNPKPDITWSKDGKVLEKGERYDFEEDKRNNKF---TLVIKEVEIDDKG 666 Query: 177 RYQCIARNAAGTRESAIATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVL 234 YQ A+N G + P I + V + S V F+ R G P P++ Sbjct: 667 AYQVTAKNYLGEASAQAILTPYSETPIFSEILPKKPVECKDRSDVEFKVRCSGIPRPNLK 726 Query: 235 WRR-SAGGGNMPLGRVKVLDDGS-----LRLDNVILADEGEYSCEAENSVGAVSASGYLT 288 W R + ++ + +DG+ + +D G+ +C A N G+ S L Sbjct: 727 WLRCNEEIREDDRYKIVIQEDGNNVESVCSITTFCPSDVGKITCRASNIYGSAQTSCDLL 786 Query: 289 VY--DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHA 346 V P +NL P S V+ G G P P + W +G + I P D++ Sbjct: 787 VQLITPSFVNLLPKSTEVDEGGCLELKAKIDGSPMPEISWYKDGEK--IVP----DEHTR 840 Query: 347 TAVF-DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPS 405 + DG T L I+ D N G V +R P + Sbjct: 841 IEILPDGTTKLIIDCVQPLDC-GAYKLVINNSTGEQ--SSLCAVAIKPERRKPSFSKSLE 897 Query: 406 NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND--GTLVLK--DLDKSD 461 + + + + P P + W+ G L Q N+ G + L+ D Sbjct: 898 DVKIVVGEPLKLEAQVVAFPNPEVQWFKNGIPLRQTKEMYFINEPIGIIGLRIDSCRPED 957 Query: 462 SGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVT 521 +GTY+ S+ G+ + + ++ +S + G P K + + Sbjct: 958 AGTYSMTVSNSLGETTGTAKVEIEEKERRPEFVVNLQPLSVMEGFPAKMEVKVLGKPTPR 1017 Query: 522 LSWSQNNK 529 L W +N + Sbjct: 1018 LQWFKNGE 1025 Score = 79.4 bits (187), Expect = 6e-13 Identities = 106/499 (21%), Positives = 191/499 (38%), Gaps = 32/499 (6%) Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLFFLRATH 73 I++ DVT + G+P P I W K G VL + + F Sbjct: 599 IQELNDVTTNVGESLAWQAIIKGNPKPDITWSKDGKVLEKGERYDFEEDKRNNKFTLVIK 658 Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133 D G Y A N G A ++ + + P+ + + V + Sbjct: 659 EVEIDDKGAYQVTAKNYLGEASAQAILTPYSETPIFSEILPKKPVECKDRSDVEFKVRCS 718 Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-----IQDARQTDAGRYQCIARNAAGT 188 G P PN+ W + + + D ++ + + GN V I +D G+ C A N G+ Sbjct: 719 GIPRPNLKWLRCNEEIREDDRYKIVIQEDGNNVESVCSITTFCPSDVGKITCRASNIYGS 778 Query: 189 RESAIATLKIHIKPYLIT-GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP-- 245 +++ L I P + P+ G + + ++ G P+P++ W + G +P Sbjct: 779 AQTSCDLLVQLITPSFVNLLPKSTEVDEGGCLELKAKIDGSPMPEISWYKD-GEKIVPDE 837 Query: 246 LGRVKVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLSPN 300 R+++L DG+ +L D V D G Y NS G S+ + + PS + S Sbjct: 838 HTRIEILPDGTTKLIIDCVQPLDCGAYKLVINNSTGEQSSLCAVAIKPERRKPSFSKSLE 897 Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360 V + G + P P + W G I +++ Y G+ L I D Sbjct: 898 DVKIVVGEPLKLEAQVVAFPNPEVQWFKNG----IPLRQTKEMYFINEPI-GIIGLRI-D 951 Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN--QTLPIKSMAVFP 418 + + + T + N G + K+ + + RP ++ P + + P K M V Sbjct: 952 SCRPEDAGTYSMTVSNSLGETTGTAKVEIEEKERRPEFVVNLQPLSVMEGFPAK-MEV-- 1008 Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGT--LVLKDLDKSDSGTYTCVASSRH 473 + P P + W+ GE ++ + +R DG+ L+++ D+G Y +A + Sbjct: 1009 -KVLGKPTPRLQWFKNGEEIVPDGKRVKAVSMADGSQALIIEKATPEDAGEYQVIAGNTE 1067 Query: 474 GKYVWSGALLVDSPINPNI 492 G G + V + ++ Sbjct: 1068 GTSSCKGTISVVGKLQSDV 1086 Score = 70.5 bits (165), Expect = 3e-10 Identities = 77/298 (25%), Positives = 118/298 (39%), Gaps = 18/298 (6%) Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67 S + P + DV V QP L+ G+P P + W K G + + R + G Sbjct: 1087 SEQKPGFVNPMRDVYVEEGQPLNLSVSFVGNPIPDVNWSKDGA-PLQPSDRFTITCDGKK 1145 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127 + DAGVY C +N G +R +T +V + + K Q T Sbjct: 1146 TELEINPCEGKDAGVYECRISNPLGEDSTR-STANVRKIFQPPSFIHAFKDLQQLPTFDA 1204 Query: 128 ECLP-PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARN 184 + L G P P++ W N + ++ D D DG L ++D D+G Y+C A N Sbjct: 1205 KFLARVSGVPRPDITWYVNEKPIVQDDDKYKIKRDGDACCLYVKDCTYDDSGVYKCRAVN 1264 Query: 185 AAGTRESA--------IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 G E A I ++ P + D G F V G P PD W Sbjct: 1265 KGGEAECAANLTIVDEIGKIQKFEPPSFLKRIGDCEMYKGMPAKFTACVTGIPEPDFEWF 1324 Query: 237 RSAGGGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291 + G R+++ +GS L ++NV D G+Y+ + N G S + L +Y+ Sbjct: 1325 HN-GDKMWQTDRIRMDQEGSLLRLTINNVDELDAGKYTLKISNPHGEDSCTADL-IYE 1380 Score = 62.5 bits (145), Expect = 7e-08 Identities = 89/387 (22%), Positives = 143/387 (36%), Gaps = 37/387 (9%) Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT---DAGRYQC 180 T+V E + P + W K+G+ L R+ + G + + D G Y C Sbjct: 412 TIVFE-VEATSLPRADAKWFKDGKPLR--SGERVRIESSGERFRMELSKIIIEDEGVYTC 468 Query: 181 IARNAAGTRES----AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 N G + + T+ +P I +DV G S F+ DP+PD+ W Sbjct: 469 SFSNKLGEDMTEGYLTVQTVDELRRPKFIETLQDVDVANGKSGMFKAMFTADPVPDITWY 528 Query: 237 RSAGGGNMPLGRVKVLDD---GSLRLDNVILA---------DEGEYSCEAENSVGAVSAS 284 + R+K+ D GS +L + D GEY+ + +N G ++ Sbjct: 529 FKGDEIHSEDSRLKITVDNKPGSDKLTETTVTLSVPKCSKDDTGEYTLKLKNKYGEAESN 588 Query: 285 GYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344 +L + P I N V G + G P+P + WS +G ++ G D Sbjct: 589 AFLNLLLCPEIQ-ELNDVTTNVGESLAWQAIIKGNPKPDITWSKDGK--VLEKGERYDFE 645 Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404 + L I + + +D + +A NY G + + LT S+ I+ P Sbjct: 646 EDKR--NNKFTLVIKEVEIDD-KGAYQVTAKNYLGEASAQAILTPYSETPIFSEILPKKP 702 Query: 405 SNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT--NDGTLV-----LKDL 457 +S F P P + W E + ++ R + DG V + Sbjct: 703 VE--CKDRSDVEFKVRCSGIPRPNLKWLRCNEEIREDDRYKIVIQEDGNNVESVCSITTF 760 Query: 458 DKSDSGTYTCVASSRHGKYVWSGALLV 484 SD G TC AS+ +G S LLV Sbjct: 761 CPSDVGKITCRASNIYGSAQTSCDLLV 787 Score = 51.6 bits (118), Expect = 1e-04 Identities = 49/220 (22%), Positives = 88/220 (40%), Gaps = 30/220 (13%) Query: 381 SFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ 440 S+ + + S + P P + + A C A+ +P+P+I WY + + Sbjct: 2212 SYAEAEAMLESKKEGHLPFFREKPQIKPIEEGKPAQLACLAVGSPKPLIQWYKNDMMVQE 2271 Query: 441 NHRRNVTND----GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFR 496 +R +T D L + D G+Y VA + G+ V V + I + F Sbjct: 2272 TNRIKITEDQDGRSILSFNPTKEHDVGSYKVVARNSLGQTV------VRTRI---VEAF- 2321 Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556 +P P P +V+DT + + W Q G+S +L Y ++ +++ Sbjct: 2322 ------VPSGPDSPELVDVSDTEILVRWKQPKHDGNSPVLCYNLQYKEGDSID------- 2368 Query: 557 SRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596 W+ IA + Y++++L TY F + N G S Sbjct: 2369 ---WIDIASNIDHEFYLIRNLKADTTYNFRLAARNRIGWS 2405 Score = 50.4 bits (115), Expect = 3e-04 Identities = 42/161 (26%), Positives = 63/161 (39%), Gaps = 6/161 (3%) Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRES 191 G P+P + + N Q + G G L I + D G Y+ +A N G Sbjct: 1571 GYPKPKMTYYFNDQPIESGGRYDQSYTRNGQATLFINRMLERDEGLYEAVASNEHGEARQ 1630 Query: 192 AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS---AGGGNMPLGR 248 + L+I P I PE+ + RV G P P++ W + + Sbjct: 1631 RVC-LRIAEYPTFIHRPEETIVMIRRIGQLTARVTGVPYPEIKWYKDWKPLTTSSRIRIE 1689 Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 K D L + + ++ DEG YS A N G++S S L V Sbjct: 1690 FKEPDTSLLIISDTMVKDEGLYSVSARNVAGSISCSVMLHV 1730 Score = 48.4 bits (110), Expect = 0.001 Identities = 66/295 (22%), Positives = 111/295 (37%), Gaps = 32/295 (10%) Query: 202 PYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGS--- 256 P++I D ++ F+ P D W + G + G RV++ G Sbjct: 395 PHIIKSTLADKTVYETQTIVFEVEATSLPRADAKWFKD--GKPLRSGERVRIESSGERFR 452 Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-----PPSINLSPNSVNVESGNVAR 311 + L +I+ DEG Y+C N +G GYLTV P + V+V +G Sbjct: 453 MELSKIIIEDEGVYTCSFSNKLGEDMTEGYLTVQTVDELRRPKFIETLQDVDVANGKSGM 512 Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSR------DKYHATAVFDGVTVLTINDTDKND 365 F T P P + W +G+ I SR +K + + + L++ K+D Sbjct: 513 FKAMFTADPVPDITWYFKGDE--IHSEDSRLKITVDNKPGSDKLTETTVTLSVPKCSKDD 570 Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425 + N G + L + P I ++ T + + P Sbjct: 571 T-GEYTLKLKNKYGEAESNAFLNLL----LCPEI--QELNDVTTNVGESLAWQAIIKGNP 623 Query: 426 EPIIAWYFEGEALIQNHRRNVTNDG-----TLVLKDLDKSDSGTYTCVASSRHGK 475 +P I W +G+ L + R + D TLV+K+++ D G Y A + G+ Sbjct: 624 KPDITWSKDGKVLEKGERYDFEEDKRNNKFTLVIKEVEIDDKGAYQVTAKNYLGE 678 Score = 45.6 bits (103), Expect = 0.008 Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL--PAGGL 66 G P+ E+P + +PA L C A GSP P I+WYK ++V +T+R + G Sbjct: 2226 GHLPFFREKPQIKPIEEGKPAQLACLAVGSPKPLIQWYKND-MMVQETNRIKITEDQDGR 2284 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYG 92 L + H D G Y A NS G Sbjct: 2285 SILSFNPTKEH-DVGSYKVVARNSLG 2309 Score = 43.2 bits (97), Expect = 0.044 Identities = 26/100 (26%), Positives = 46/100 (46%), Gaps = 3/100 (3%) Query: 390 TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND 449 ++++ PP II + +++T+ VF A P W+ +G+ L R + + Sbjct: 388 STEESAPPHIIKSTLADKTVYETQTIVFEVEATSLPRADAKWFKDGKPLRSGERVRIESS 447 Query: 450 GTLVLKDLDK---SDSGTYTCVASSRHGKYVWSGALLVDS 486 G +L K D G YTC S++ G+ + G L V + Sbjct: 448 GERFRMELSKIIIEDEGVYTCSFSNKLGEDMTEGYLTVQT 487 Score = 41.5 bits (93), Expect = 0.14 Identities = 28/104 (26%), Positives = 54/104 (51%), Gaps = 11/104 (10%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV---DGGNLV 166 FR +P+ K +G L CL GSP+P + W KN ++ +R+ + DG +++ Sbjct: 2231 FREKPQIKPIEEGKPAQLACLAV-GSPKPLIQWYKND--MMVQETNRIKITEDQDGRSIL 2287 Query: 167 -IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209 ++ D G Y+ +ARN+ G + +I ++ ++ +GP+ Sbjct: 2288 SFNPTKEHDVGSYKVVARNSLG---QTVVRTRI-VEAFVPSGPD 2327 Score = 36.3 bits (80), Expect = 5.1 Identities = 33/112 (29%), Positives = 45/112 (40%), Gaps = 5/112 (4%) Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138 D G+Y A+N +G AR R L +A F PE + + G P P Sbjct: 1613 DEGLYEAVASNEHGEARQR-VCLRIAEY-PTFIHRPE-ETIVMIRRIGQLTARVTGVPYP 1669 Query: 139 NVYWKKNGQTLLFDGDSRMHLV--DGGNLVIQDARQTDAGRYQCIARNAAGT 188 + W K+ + L R+ D L+I D D G Y ARN AG+ Sbjct: 1670 EIKWYKDWKPLTTSSRIRIEFKEPDTSLLIISDTMVKDEGLYSVSARNVAGS 1721 >UniRef50_A2CEC7 Cluster: Novel protein similar to Down syndrome cell adhesion molecule; n=1; Danio rerio|Rep: Novel protein similar to Down syndrome cell adhesion molecule - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 1904 Score = 163 bits (397), Expect = 2e-38 Identities = 207/841 (24%), Positives = 340/841 (40%), Gaps = 91/841 (10%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT-HRS--ILPAGG--L 66 P I+ + V+ ++P +L C G+P P + W V+ D+ HR I+ G L Sbjct: 237 PKILSAFSEKVVSPNEPISLVCHVKGTPLPTVTWTLDDDPVIKDSNHRMDRIITTEGHVL 296 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTV 125 +L +H +V SD GVY C NS G+ S A ++V R + P +A G Sbjct: 297 SYLNVSHTQV-SDGGVYRCTCNNSAGSV-SYQARINV---RGPASIRPMKNVTAIAGRDT 351 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC--IAR 183 + C G P ++ W K+ L F+ R + G L + + + +D G Y C + Sbjct: 352 YIHCRII-GYPYYSIKWYKDSNLLPFNHRQRA-FENNGTLKLSNVQNSDEGEYTCYVLVD 409 Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRRSAGGG 242 S T+K+ P LI + A G V C V LP + W + Sbjct: 410 PEKQIHRSVHVTVKV---PPLIQHSDSQSASIGQRVFIPCVVISGDLPMSITWHKDGRPI 466 Query: 243 NMPLG-RVKVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300 N LG + +D SLR+ N+ G Y+C A N AV S L V PP + P Sbjct: 467 NASLGVTIDNIDFTSSLRISNLSEIHNGSYTCIARNEAAAVEHSIQLIVKVPPHFEVQPK 526 Query: 301 SVNVESGNVARFTCTATGRPEPTMFWS-VEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359 + G C+A G P PT+ W+ +G F ++ + + + ++L I Sbjct: 527 DQDGIYGKSVTLNCSAKGNPIPTIVWNHSKGAGVPQFQPIALNSGSRVQLLENGSLL-IK 585 Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGK-LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418 + D+ +C N G+ + LTV + P +IT+ P+ M Sbjct: 586 HVLEEDA-GFYLCKVSNDVGADISKSMYLTV-----KIPAMITSYPNTTRAEQGHMTEMS 639 Query: 419 CTAICTPEPIIAWYFEGEALIQNHRR---NVTNDGTLVLKDLD-----KSDSGTYTCVAS 470 CTA + W E + + R V G V+ L + DSG ++C+A Sbjct: 640 CTAHGEKPIKVRWEKESHIINPDMSRYVVTVKEVGDEVISTLQILHTVREDSGFFSCIAI 699 Query: 471 SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530 + +G+ D I I V P PP I V D ++ L W+ Sbjct: 700 NSYGE---------DKGIIQLI-------VQDRPDPPEVEI-REVKDRTIALRWTMGFD- 741 Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590 G+S I GY + + ++ S ++ ++ +++Q + L P TY + + Sbjct: 742 GNSPITGYDIN-YKNKSASWASSQMTKD----VSPQLNQA--TIIELHPASTYNIRMFAK 794 Query: 591 NSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIK 650 N G S P S+ +T+ D D + ++ I S+ IK Sbjct: 795 NQIGESRP---SNELTITTDEAP------------------PDGAPQDVQLEAISSQGIK 833 Query: 651 LMWEILNFYYLEGLF----IYFRPL-DNITIEYEMKTILHSNDVSGFEITSLRKYTKYEF 705 + W+ + + GL + +R + +Y + + D+ + +L+KYT+YE Sbjct: 834 VTWKPPHKHLQNGLIRSYQVCYREFGTGGSPQYNTINVDTTGDIETLTLDNLKKYTQYEV 893 Query: 706 FLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIIT 765 + + G S TL+DVP PP N+ T+ L WS + NG++ Sbjct: 894 RVQAANRAGMGPTSEEITITTLEDVPSRPPENVVTTATTPETISLSWSALPKEALNGMLL 953 Query: 766 GYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825 GY V+ W ++P + N T + SL + L +YS+Q+ A T G G S+++ Sbjct: 954 GYRVIF-WANLPDGELGEIRNITTTK-PSLELERLEKYTNYSIQVLAFTRAGDGVRSEQI 1011 Query: 826 Y 826 Y Sbjct: 1012 Y 1012 Score = 124 bits (300), Expect = 1e-26 Identities = 119/470 (25%), Positives = 195/470 (41%), Gaps = 38/470 (8%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDT--HRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88 L C+A G P P RW + + SD+ H+S+ GL + AT SDAG Y CE Sbjct: 74 LPCKASGHPPPRYRWLRDNSPLESDSRYHQSV---SGLL-IEATRP---SDAGSYVCEVW 126 Query: 89 NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148 NS+G A+ + L+ + P + + G V L C GS E ++ W +N + Sbjct: 127 NSFGNAKVVGRLVVKQPLKAV--VSPRKVRGSVGSQVSLFC-SVTGSDEFDITWYRNAEK 183 Query: 149 LLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208 + + R+ ++ NLV++ ++D G YQC ARN + + + + P +++ Sbjct: 184 IYQGINVRITGINNENLVMEGMAKSDGGAYQCFARNGKMSTQDLVQVVLEDGTPKILSAF 243 Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGGGNMPLGRVKVLDDGSLRLDNVI- 263 + V ++ C V G PLP V W N + R+ + L NV Sbjct: 244 SEKVVSPNEPISLVCHVKGTPLPTVTWTLDDDPVIKDSNHRMDRIITTEGHVLSYLNVSH 303 Query: 264 --LADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPE 321 ++D G Y C NS G+VS + V P SI N V +G C G P Sbjct: 304 TQVSDGGVYRCTCNNSAGSVSYQARINVRGPASIRPMKN-VTAIAGRDTYIHCRIIGYPY 362 Query: 322 PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381 ++ W + N + P R + F+ L +++ +D V+ Sbjct: 363 YSIKWYKDSN---LLPFNHRQR-----AFENNGTLKLSNVQNSDEGEYTCYVLVDPEKQI 414 Query: 382 FVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGEALIQ 440 +TV + PP+I + S Q+ I PC I P+ I W+ +G + Sbjct: 415 HRSVHVTV-----KVPPLIQHSDS-QSASIGQRVFIPCVVISGDLPMSITWHKDGRPINA 468 Query: 441 NHRRNVTN---DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 + + N +L + +L + +G+YTC+A + S L+V P Sbjct: 469 SLGVTIDNIDFTSSLRISNLSEIHNGSYTCIARNEAAAVEHSIQLIVKVP 518 Score = 74.5 bits (175), Expect = 2e-11 Identities = 88/350 (25%), Positives = 131/350 (37%), Gaps = 33/350 (9%) Query: 155 SRMHLVDGGNLVIQDARQTDAGR-YQCIARN--AAGTRESAIATL----KIHIKPYLITG 207 SR + G L I D + DA Y+C R+ TR+S A L + P ++ G Sbjct: 1 SRYLITSTGALYILDVQSEDAVNIYRCTTRHRYTGETRQSNSARLLLSEPVDSAPVILDG 60 Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD--GSLRLDNVILA 265 E G V C+ G P P W R N PL L ++ + Sbjct: 61 FERKEVMVGHRVELPCKASGHPPPRYRWLRD----NSPLESDSRYHQSVSGLLIEATRPS 116 Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325 D G Y CE NS G G L V P +SP V G+ C+ TG E + Sbjct: 117 DAGSYVCEVWNSFGNAKVVGRLVVKQPLKAVVSPRKVRGSVGSQVSLFCSVTGSDEFDIT 176 Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385 W N I+ G++ T + + L + K+D C A N G + Sbjct: 177 W--YRNAEKIYQGIN---VRITGINN--ENLVMEGMAKSDG-GAYQCFARN--GKMSTQD 226 Query: 386 KLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ--NHR 443 + V +D P I + S + + C TP P + W + + +I+ NHR Sbjct: 227 LVQVVLEDGTPK--ILSAFSEKVVSPNEPISLVCHVKGTPLPTVTWTLDDDPVIKDSNHR 284 Query: 444 --RNVTNDGTLV----LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 R +T +G ++ + SD G Y C ++ G + + V P Sbjct: 285 MDRIITTEGHVLSYLNVSHTQVSDGGVYRCTCNNSAGSVSYQARINVRGP 334 Score = 56.8 bits (131), Expect = 3e-06 Identities = 51/189 (26%), Positives = 79/189 (41%), Gaps = 9/189 (4%) Query: 637 ELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITI-EYEMKTILHSNDVS-GFEI 694 E + T +TI L W L L G+ + +R + + + E+ I + E+ Sbjct: 924 ENVVTTATTPETISLSWSALPKEALNGMLLGYRVIFWANLPDGELGEIRNITTTKPSLEL 983 Query: 695 TSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSP 754 L KYT Y ++ F + +G S +T +DVP GPP ++ ++ V + W P Sbjct: 984 ERLEKYTNYSIQVLAFTRAGDGVRSEQIYTRTKEDVP-GPPAGVKAAASTSSVVFVSWLP 1042 Query: 755 PELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAET 814 P NGII Y +V P S V+ +TNL YS+ + A T Sbjct: 1043 P--HKLNGIIRKY-IVFCSNPYPTVISEFEAAPDVYFRR---LTNLNQNWQYSIWVVAVT 1096 Query: 815 IIGLGPFSQ 823 G G S+ Sbjct: 1097 AAGRGNTSE 1105 Score = 47.2 bits (107), Expect = 0.003 Identities = 33/105 (31%), Positives = 45/105 (42%), Gaps = 5/105 (4%) Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF 433 AV AG +TV P I+T T P V PC A+ P P I W Sbjct: 1094 AVTAAGRGNTSEIITVEPQAKAPARILTFS-GTVTTPWMRDIVLPCKAVGDPPPTIKWLK 1152 Query: 434 EGEA----LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 + + RR+ N+G+ V++ + DSG Y CVAS+ G Sbjct: 1153 GNNGTPAPVSIDGRRSAHNNGSFVIRTVKAEDSGYYRCVASNNWG 1197 Score = 45.6 bits (103), Expect = 0.008 Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 6/95 (6%) Query: 125 VVLECLPPRGSPEPNVYWKK--NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182 +VL C G P P + W K NG D R + G+ VI+ + D+G Y+C+A Sbjct: 1134 IVLPCKAV-GDPPPTIKWLKGNNGTPAPVSIDGRRSAHNNGSFVIRTVKAEDSGYYRCVA 1192 Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGS 217 N G+ E L + ++ Y++ ED + GS Sbjct: 1193 SNNWGSDE---IMLNLQVQGYILQYSEDNSEEWGS 1224 Score = 41.1 bits (92), Expect = 0.18 Identities = 43/165 (26%), Positives = 66/165 (40%), Gaps = 23/165 (13%) Query: 181 IARNAAGT-RESAIATLKIHIKP--YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 +A AAG S I T++ K ++T V + C+ GDP P + W + Sbjct: 1093 VAVTAAGRGNTSEIITVEPQAKAPARILTFSGTVTTPWMRDIVLPCKAVGDPPPTIKWLK 1152 Query: 238 SAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA------VSASGYLT 288 G P+ GR ++GS + V D G Y C A N+ G+ + GY+ Sbjct: 1153 GNNGTPAPVSIDGRRSAHNNGSFVIRTVKAEDSGYYRCVASNNWGSDEIMLNLQVQGYIL 1212 Query: 289 VYDPP------SINLSPNS-----VNVESGNVARFTCTATGRPEP 322 Y S ++SP+ N++ G +FT TA P Sbjct: 1213 QYSEDNSEEWGSYSISPSERSYRLENLKCGTWYKFTLTAQNAVGP 1257 Score = 39.9 bits (89), Expect = 0.41 Identities = 32/135 (23%), Positives = 55/135 (40%), Gaps = 3/135 (2%) Query: 356 LTINDTDKNDSRNTIVCSAVN-YAGSSFVRGKLTVT-SDDDRPPPIITNGPSNQTLPIKS 413 L I D D+ N C+ + Y G + + S+ P+I +G + + + Sbjct: 11 LYILDVQSEDAVNIYRCTTRHRYTGETRQSNSARLLLSEPVDSAPVILDGFERKEVMVGH 70 Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473 PC A P P W + L + R + + G L+++ SD+G+Y C + Sbjct: 71 RVELPCKASGHPPPRYRWLRDNSPLESDSRYHQSVSG-LLIEATRPSDAGSYVCEVWNSF 129 Query: 474 GKYVWSGALLVDSPI 488 G G L+V P+ Sbjct: 130 GNAKVVGRLVVKQPL 144 Score = 38.3 bits (85), Expect = 1.3 Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 6/76 (7%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGG---VLVVSDTHRSILPAGGLFFLRATHGRVH 77 VT + L C+A G P P I+W KG VS R G F +R Sbjct: 1126 VTTPWMRDIVLPCKAVGDPPPTIKWLKGNNGTPAPVSIDGRRSAHNNGSFVIRTVKA--- 1182 Query: 78 SDAGVYWCEATNSYGT 93 D+G Y C A+N++G+ Sbjct: 1183 EDSGYYRCVASNNWGS 1198 >UniRef50_Q8NDA2 Cluster: Hemicentin-2; n=28; Euteleostomi|Rep: Hemicentin-2 - Homo sapiens (Human) Length = 1340 Score = 163 bits (395), Expect = 3e-38 Identities = 136/483 (28%), Positives = 200/483 (41%), Gaps = 31/483 (6%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64 ++T +P + P V + L C A G P P I W K G+ V + +LP G Sbjct: 838 FLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGG 897 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124 L R H DAG Y C A NS G+A + T V + + +G Sbjct: 898 QL---RIAHASPE-DAGNYLCIAKNSAGSAMGK--TRLVVQVPPVIENGLPDLSTTEGSH 951 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 L C RGSPEPN+ W K+GQ + + + + G L++++ DAG Y C A N Sbjct: 952 AFLPC-KARGSPEPNITWDKDGQPVS-GAEGKFTIQPSGELLVKNLEGQDAGTYTCTAEN 1009 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 A G + L I + P T P D + G + +C G P P + W + + Sbjct: 1010 AVGRARRRVH-LTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVN----DR 1064 Query: 245 PLGRVKVLDDGSLRLDNVILA--DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302 P+ DG L ++ D G Y C AEN VG A ++ V + P + S Sbjct: 1065 PVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGEAFSY 1124 Query: 303 NVES-GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361 VE G + C G P P + W +G P R + + +G LTI+ T Sbjct: 1125 LVEPVGGSIQLDCVVRGDPVPDIHWIKDG-----LP--LRGSHLRHQLQNGS--LTIHRT 1175 Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421 +++D+ C A N G V K+ + P + P + T+ C A Sbjct: 1176 ERDDA-GRYQCLAENEMG---VAKKVVILVLQSAP--VFQVEPQDMTVRSGDDVALRCQA 1229 Query: 422 ICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481 P P I W G+ L + R DG+L L++++ D+GTY CVA + G Sbjct: 1230 TGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARAF 1289 Query: 482 LLV 484 L+V Sbjct: 1290 LVV 1292 Score = 162 bits (394), Expect = 5e-38 Identities = 130/470 (27%), Positives = 196/470 (41%), Gaps = 26/470 (5%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAG 64 VT P I + D TV P L C + G P+P + W K G L + + P+G Sbjct: 748 VTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSG 807 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124 L +A +H AG Y C A NS G A ++ L V L P ++ + Sbjct: 808 ALEIGQALP--IH--AGRYTCSARNSAGVAH-KHVFLTVQASPVVKPL-PSVVRAVAEEE 861 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 V+L C G P P + W+K G + +++ + GG L I A DAG Y CIA+N Sbjct: 862 VLLPC-EASGIPRPTITWQKEGLNVATGVSTQV--LPGGQLRIAHASPEDAGNYLCIAKN 918 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 +AG+ L + + P + G D+ GS C+ G P P++ W + + Sbjct: 919 SAGSAMGK-TRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSG 977 Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304 G+ + G L + N+ D G Y+C AEN+VG +LT+ P P ++ Sbjct: 978 AEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSL 1037 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 G+ C A G P P + W+V N + G+S DG + L + Sbjct: 1038 RLGDRLWLRCAARGSPTPRIGWTV--NDRPVTEGVSEQ--------DGGSTLQRAAVSRE 1087 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424 DS T VC A N G + + V P + S P+ C Sbjct: 1088 DS-GTYVCWAENRVGRTQAVSFVHV----KEAPVLQGEAFSYLVEPVGGSIQLDCVVRGD 1142 Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 P P I W +G L +H R+ +G+L + ++ D+G Y C+A + G Sbjct: 1143 PVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMG 1192 Score = 140 bits (340), Expect = 2e-31 Identities = 130/452 (28%), Positives = 183/452 (40%), Gaps = 32/452 (7%) Query: 29 ATLNCRAGGSPSPAIRWYKGGVLV---VSDTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85 A L C A GSP P + W+K G + + +LP+ L L G D+ + C Sbjct: 678 ALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNAL--LLTAPG--PQDSAQFEC 733 Query: 86 EATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK 144 +N G A R T+HV + + + A VVL C G P P V W K Sbjct: 734 VVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMA---PVVLTC-HSTGIPAPTVSWSK 789 Query: 145 NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL 204 G L G S + G L I A AGRY C ARN+AG + L + P + Sbjct: 790 AGAQLGARG-SGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHV-FLTVQASPVV 847 Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNVI 263 P V A V C G P P + W++ G N+ G +VL G LR+ + Sbjct: 848 KPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKE--GLNVATGVSTQVLPGGQLRIAHAS 905 Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPT 323 D G Y C A+NS G+ L V PP I ++ G+ A C A G PEP Sbjct: 906 PEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPN 965 Query: 324 MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383 + W +G +S + T G L + + + D+ T C+A N G + Sbjct: 966 ITWDKDGQ------PVSGAEGKFTIQPSG--ELLVKNLEGQDA-GTYTCTAENAVGRARR 1016 Query: 384 RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR 443 R LT+ P+ T P +++L + C A +P P I W + + Sbjct: 1017 RVHLTIL-----VLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVS 1071 Query: 444 RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 TL + + DSGTY C A +R G+ Sbjct: 1072 EQ-DGGSTLQRAAVSREDSGTYVCWAENRVGR 1102 Score = 131 bits (316), Expect = 1e-28 Identities = 136/492 (27%), Positives = 209/492 (42%), Gaps = 36/492 (7%) Query: 10 EAPYIIEQPLDVTVAR--HQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67 + P E P TV++ P L C G P+P + W K + V S ++ GG Sbjct: 34 QVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRL 93 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127 L + AG Y C A N+ AR + R +G V L Sbjct: 94 QLSRLQP---AQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRL 150 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFD-GDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186 +C G P P+V W K+G L D G +DGG+LV++ +DAG Y C+A N A Sbjct: 151 DC-EADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLWASDAGAYTCVAHNPA 209 Query: 187 GTRESAIATLKIHIKPYLITGPE---DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 G ++ + T+ + + P + G + +V++ G VT C V G P V W + G Sbjct: 210 G-EDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKD--GLP 266 Query: 244 MPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301 +PL + +L +LR+ V LAD G ++C A + G A T+ P ++ S S Sbjct: 267 LPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGV--ADRNFTLQCP--LSWSRWS 322 Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361 + + RP S G + + + ++ G + L + Sbjct: 323 SRMTWWWFVAPWWNSRARPGAFPCLSCRGMK-------DGEPLLSQSLEQGPS-LQLEAV 374 Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG-PSNQTLPIKSMAVFPCT 420 DS T C AV+ AG + +LTV PP I +G P+ +L + C Sbjct: 375 GAGDS-GTYSCVAVSEAGEARRHFQLTVM----EPPHIEDSGQPTELSLTPGAPMELLCD 429 Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480 A TP+P I W+ +G+AL + N L ++++ D+G YTC+A S G S Sbjct: 430 AQGTPQPNITWHKDGQALTR-LENNSRATRVLRVENVQVRDAGLYTCLAESPAGAIEKSF 488 Query: 481 ALLVDSPINPNI 492 + V +P PNI Sbjct: 489 RVRVQAP--PNI 498 Score = 122 bits (294), Expect = 6e-26 Identities = 123/475 (25%), Positives = 190/475 (40%), Gaps = 48/475 (10%) Query: 6 VTSGEAPYIIE--QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63 +T E P+I + QP ++++ P L C A G+P P I W+K G + + S Sbjct: 399 LTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATR 458 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG- 122 LR + +V DAG+Y C A + G + V V + P + G Sbjct: 459 ----VLRVENVQVR-DAGLYTCLAESPAGAIEK---SFRVRVQAPPNIVGPRGPRFVVGL 510 Query: 123 --DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180 +VLEC P P + W ++G L D ++ G L +Q D+G Y C Sbjct: 511 APGQLVLEC-SVEAEPAPKITWHRDGIVLQEDAHTQFP-ERGRFLQLQALSTADSGDYSC 568 Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 ARNAAG+ A ++IH P + +GP V + C+ G P P V WR+ Sbjct: 569 TARNAAGSTSVAFR-VEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRV 627 Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300 + R ++L +GSLR+ V+ D G Y C A NS G+ L V Sbjct: 628 PLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRV----------- 676 Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360 +A C A+G P+P + W +G + + + Y L + Sbjct: 677 --------LALLPCEASGSPKPLVVWWKDGQKLDF--RLQQGAYRLLP----SNALLLTA 722 Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420 DS C N G + ++TV PP I + ++ T+ + + V C Sbjct: 723 PGPQDSAQ-FECVVSNEVGEAHRLYQVTV-----HVPPTIADDQTDFTVTMMAPVVLTCH 776 Query: 421 AICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 + P P ++W G L + V+ G L + +G YTC A + G Sbjct: 777 STGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAG 831 Score = 119 bits (287), Expect = 4e-25 Identities = 118/460 (25%), Positives = 175/460 (38%), Gaps = 45/460 (9%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 L C P+P I W++ G+++ D H G L+A +D+G Y C A N+ Sbjct: 517 LECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALST---ADSGDYSCTARNA 573 Query: 91 YG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149 G T+ + +H R P + + T +L C G P P V W+K+ + Sbjct: 574 AGSTSVAFRVEIHTV---PTIRSGPPAVNVSVNQTALLPCQAD-GVPAPLVSWRKD-RVP 628 Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209 L R ++ G+L IQ DAG Y C+A N+AG+ + + P Sbjct: 629 LDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLALLP------- 681 Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL--GRVKVLDDGSLRLDNVILADE 267 C G P P V+W + + L G ++L +L L D Sbjct: 682 -------------CEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDS 728 Query: 268 GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327 ++ C N VG +TV+ PP+I V TC +TG P PT+ WS Sbjct: 729 AQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWS 788 Query: 328 VEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387 G + G Y + G + + R T CSA N AG + L Sbjct: 789 KAGAQL----GARGSGYRVSP--SGALEIG-QALPIHAGRYT--CSARNSAGVAHKHVFL 839 Query: 388 TVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT 447 TV + P++ PS + + PC A P P I W EG + V Sbjct: 840 TVQAS-----PVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVL 894 Query: 448 NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 G L + D+G Y C+A + G + L+V P Sbjct: 895 PGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVP 934 Score = 110 bits (264), Expect = 3e-22 Identities = 73/252 (28%), Positives = 115/252 (45%), Gaps = 11/252 (4%) Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138 D+G Y C A + G AR + E +P G + L C +G+P+P Sbjct: 378 DSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLC-DAQGTPQP 436 Query: 139 NVYWKKNGQTLL-FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197 N+ W K+GQ L + +SR V L +++ + DAG Y C+A + AG E + ++ Sbjct: 437 NITWHKDGQALTRLENNSRATRV----LRVENVQVRDAGLYTCLAESPAGAIEKSFR-VR 491 Query: 198 IHIKPYLI--TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255 + P ++ GP VV + +C V +P P + W R G + + G Sbjct: 492 VQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRD-GIVLQEDAHTQFPERG 550 Query: 256 S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314 L+L + AD G+YSC A N+ G+ S + + ++ P+I P +VNV A C Sbjct: 551 RFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPC 610 Query: 315 TATGRPEPTMFW 326 A G P P + W Sbjct: 611 QADGVPAPLVSW 622 Score = 102 bits (244), Expect = 7e-20 Identities = 114/460 (24%), Positives = 200/460 (43%), Gaps = 53/460 (11%) Query: 30 TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89 T+ C GSP + W K G L + + R++L G LR + ++ +DAG++ C A + Sbjct: 245 TMVCPVRGSPPIHVSWLKDG-LPLPLSQRTLLHGSG-HTLRISKVQL-ADAGIFTCVAAS 301 Query: 90 SYGTARSRNATLHVAVL--REEFRLE----PESKQSAQGDTVVLECLPPRGSPEPNVYWK 143 G A RN TL + R R+ +++ CL RG Sbjct: 302 PAGVA-DRNFTLQCPLSWSRWSSRMTWWWFVAPWWNSRARPGAFPCLSCRGM-------- 352 Query: 144 KNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY 203 K+G+ LL L G +L ++ D+G Y C+A + AG L + P+ Sbjct: 353 KDGEPLLSQS-----LEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQ-LTVMEPPH 406 Query: 204 LITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS--LRL 259 + P ++ G+ + C G P P++ W + L R++ + LR+ Sbjct: 407 IEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDG----QALTRLENNSRATRVLRV 462 Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS----VNVESGNVARFTCT 315 +NV + D G Y+C AE+ GA+ S + V PP+I + P V + G + C+ Sbjct: 463 ENVQVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNI-VGPRGPRFVVGLAPGQLV-LECS 520 Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375 P P + W +G I+ + ++ F + + ++ D D C+A Sbjct: 521 VEAEPAPKITWHRDG---IVLQEDAHTQFPERGRF--LQLQALSTADSGDYS----CTAR 571 Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG 435 N AGS+ V ++ + + P I +GP + + A+ PC A P P+++W + Sbjct: 572 NAAGSTSVAFRVEIHT-----VPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDR 626 Query: 436 EAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 L ++ R + +G+L ++ + D+G Y C+AS+ G Sbjct: 627 VPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAG 666 Score = 85.0 bits (201), Expect = 1e-14 Identities = 84/316 (26%), Positives = 123/316 (38%), Gaps = 18/316 (5%) Query: 165 LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT-GSSVTFQC 223 L IQ+A+ +D G Y C N AG TL + + P + V+Q GS + C Sbjct: 1 LEIQEAQVSDKGLYSCKVSNVAGEAVRTF-TLTVQVPPTFENPKTETVSQVAGSPLVLTC 59 Query: 224 RVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSA 283 V G P P V W + V G L+L + A G Y+C AEN+ Sbjct: 60 DVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARK 119 Query: 284 SGYLTVYDPPSINLS--PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341 + V P I S +V G R C A G+P P + W +G+ G Sbjct: 120 DFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPL----GQDM 175 Query: 342 DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401 H DG + L + +D+ C A N AG + V PP I Sbjct: 176 GP-HLRFYLDGGS-LVLKGLWASDA-GAYTCVAHNPAGEDARLHTVNVLV----PPTIKQ 228 Query: 402 NGPSNQTLPIK--SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLD 458 + TL + + C +P ++W +G L + R + G TL + + Sbjct: 229 GADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQ 288 Query: 459 KSDSGTYTCVASSRHG 474 +D+G +TCVA+S G Sbjct: 289 LADAGIFTCVAASPAG 304 Score = 84.2 bits (199), Expect = 2e-14 Identities = 74/263 (28%), Positives = 106/263 (40%), Gaps = 17/263 (6%) Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137 SD G+Y C+ +N G A R TL V V + E+ G +VL C G P Sbjct: 9 SDKGLYSCKVSNVAGEA-VRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTC-DVSGVPA 66 Query: 138 PNVYWKKNGQTLLFDGDSRMHLV--DGGNLVIQDARQTDAGRYQCIARN--AAGTRESAI 193 P V W K+ + S +H V GG L + + AG Y C+A N A ++ + Sbjct: 67 PTVTWLKDRMPV---ESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVV 123 Query: 194 ATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKV 251 A L I+ + V+ G V C G P PDV W + +G ++ Sbjct: 124 AVLVAPRIRSSGVAREHHVLE--GQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRF 181 Query: 252 -LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV---ESG 307 LD GSL L + +D G Y+C A N G + + V PP+I + G Sbjct: 182 YLDGGSLVLKGLWASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPG 241 Query: 308 NVARFTCTATGRPEPTMFWSVEG 330 + C G P + W +G Sbjct: 242 ELVTMVCPVRGSPPIHVSWLKDG 264 Score = 41.1 bits (92), Expect = 0.18 Identities = 34/141 (24%), Positives = 60/141 (42%), Gaps = 6/141 (4%) Query: 403 GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL---IQNHRRNVTNDGTLVLKDLDK 459 G Q ++ +A+ PC A +P+P++ W+ +G+ L +Q + L+L Sbjct: 666 GSDRQGRDLRVLALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGP 725 Query: 460 SDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTS 519 DS + CV S+ G+ + V P P I + D + P H+ + Sbjct: 726 QDSAQFECVVSNEVGEAHRLYQVTVHVP--PTIADDQ-TDFTVTMMAPVVLTCHSTGIPA 782 Query: 520 VTLSWSQNNKIGSSSILGYQV 540 T+SWS+ + GY+V Sbjct: 783 PTVSWSKAGAQLGARGSGYRV 803 >UniRef50_Q5XNV8 Cluster: Neogenin/DCC long isoform; n=5; Vertebrata|Rep: Neogenin/DCC long isoform - Petromyzon marinus (Sea lamprey) Length = 1415 Score = 162 bits (394), Expect = 5e-38 Identities = 192/732 (26%), Positives = 298/732 (40%), Gaps = 89/732 (12%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVI-- 167 F LEP G VVL C P +K+G L D R HL+ G+L+I Sbjct: 47 FTLEPAGTVVVAGSPVVLSCTVDSDKPI-KFGTRKDGVLLDTVADERRHLLANGSLLIRT 105 Query: 168 ---QDARQTDAGRYQC-IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223 ++ + D+GRYQC + + G+ S A + + +P ++ + G SV C Sbjct: 106 GGHEELARIDSGRYQCEVTVHGLGSIISRPAAVTLIGEPRFVSSSLSTLVIQGDSVVLDC 165 Query: 224 RVGGDPL-PDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEA-------E 275 L +V W + G +V VL G L L N AD G+Y C+ Sbjct: 166 GAEVTGLWNEVRWFKE-GRSITEDSQVMVLSSGDLLLQNASKADGGKYFCQLVFGGRTFT 224 Query: 276 NSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII 335 N +S + P + P V+V G+ A C G P P++ W+ G +++ Sbjct: 225 NQGTNLSVLPEMESNRPCVVLRHPVDVSVRLGHTATLECVVAGFPAPSVHWT-RGTESVL 283 Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN-TIVCSAVNYAGSSFVRGKLTVTSDDD 394 S V G+ L I++ ++D+ + T + A N + KLTV Sbjct: 284 SERFS-------VVAGGI--LRIDNVQQDDAGDYTCIIKAQNETQRLYA--KLTVLE--- 329 Query: 395 RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVL 454 PP I +GP N+ + + C A P P+I+W+ G+ +I + + DG+L + Sbjct: 330 --PPRILHGPENRNASVSDDIILECQAEGRPRPVISWFQNGDLIIPDDFIQIV-DGSLHI 386 Query: 455 KDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHN 514 + SD G Y C+A S + L+V + P I L P + +T Sbjct: 387 LGVMASDEGVYQCMAESEVDGMQAAAQLVVINHAVPGI----------LASSPPRGMTAV 436 Query: 515 VTDTS-VTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYV 573 + T + LSW + S+L Y V + R + R R V +V + V Sbjct: 437 LVSTRFIRLSWRAPAE-SRGSVLHYSV-YYVRV-----GSVRERR---VDTLQVSELQLV 486 Query: 574 VKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTD 633 V L P Y F V N +GP G+ S L T + +L Sbjct: 487 VGELRPETGYSFQVVAVNQ---AGP---------GERSAPLRITT--QPEVQVPGPVLNL 532 Query: 634 HIVELIEATPIDSKTIKLMWE--ILNFYYLEGLFIYFRPLD-NITIEYEMKTILHSNDVS 690 H+V I + ++ L W+ F + +Y+ LD T E++ T D Sbjct: 533 HVV------AISTTSVSLQWDPPANVFSPIMHYKLYYMQLDGEATTEHDQDT-----DGP 581 Query: 691 GFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHL 750 F LRK+T+Y F ++ + K G S + +T DVP G P + + ++N+ +V + Sbjct: 582 SFTKEGLRKFTRYSFRVVAYNKHGPGVSSEDTIVRTYSDVPSGSPQELILEVVNSQSVLV 641 Query: 751 KWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQI 810 +W PP L+ NG ITGY ++ I T H S + L G YS ++ Sbjct: 642 RWKPPLLETHNGDITGYK---RHEGKAGRRAEAEIEETAH--LSYLAVGLDRGSEYSFRV 696 Query: 811 AAETIIGLGPFS 822 AA G GPFS Sbjct: 697 AAVNSNGTGPFS 708 Score = 109 bits (263), Expect = 3e-22 Identities = 80/284 (28%), Positives = 130/284 (45%), Gaps = 17/284 (5%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPS-PAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 P + L V + L+C A + +RW+K G + D+ +L +G L Sbjct: 144 PRFVSSSLSTLVIQGDSVVLDCGAEVTGLWNEVRWFKEGRSITEDSQVMVLSSGDLLLQN 203 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR-----LEPESKQSAQGDTV 125 A+ +D G Y+C+ T ++ L V E R P G T Sbjct: 204 ASK----ADGGKYFCQLVFGGRTFTNQGTNLSVLPEMESNRPCVVLRHPVDVSVRLGHTA 259 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 LEC+ G P P+V+W + +++L + R +V GG L I + +Q DAG Y CI + A Sbjct: 260 TLECVVA-GFPAPSVHWTRGTESVLSE---RFSVVAGGILRIDNVQQDDAGDYTCIIK-A 314 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 + A L + P ++ GPE+ A + +C+ G P P + W ++ G +P Sbjct: 315 QNETQRLYAKLTVLEPPRILHGPENRNASVSDDIILECQAEGRPRPVISWFQN-GDLIIP 373 Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 ++++D GSL + V+ +DEG Y C AE+ V + A+ L V Sbjct: 374 DDFIQIVD-GSLHILGVMASDEGVYQCMAESEVDGMQAAAQLVV 416 Score = 77.0 bits (181), Expect = 3e-12 Identities = 59/194 (30%), Positives = 95/194 (48%), Gaps = 14/194 (7%) Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73 ++ P+DV+V ATL C G P+P++ W +G V+S+ R + AGG+ LR + Sbjct: 244 VLRHPVDVSVRLGHTATLECVVAGFPAPSVHWTRGTESVLSE--RFSVVAGGI--LRIDN 299 Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPP 132 + DAG Y C T R + VL L PE++ ++ D ++LEC Sbjct: 300 VQ-QDDAGDYTCIIKAQNETQR---LYAKLTVLEPPRILHGPENRNASVSDDIILEC-QA 354 Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192 G P P + W +NG ++ D + +VD G+L I +D G YQC+A + ++A Sbjct: 355 EGRPRPVISWFQNGDLII--PDDFIQIVD-GSLHILGVMASDEGVYQCMAESEVDGMQAA 411 Query: 193 IATLKI-HIKPYLI 205 + I H P ++ Sbjct: 412 AQLVVINHAVPGIL 425 Score = 46.4 bits (105), Expect = 0.005 Identities = 63/225 (28%), Positives = 96/225 (42%), Gaps = 20/225 (8%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P I+ P + + L C+A G P P I W++ G L++ D I+ G L L Sbjct: 329 EPPRILHGPENRNASVSDDIILECQAEGRPRPVISWFQNGDLIIPDDFIQIVD-GSLHIL 387 Query: 70 RATHGRVHSDAGVYWCEATNSYG--TARSRNATLHVAVLREEFRLEPESKQSAQGDT--V 125 G + SD GVY C A + A ++ ++ AV P + T + Sbjct: 388 ----GVMASDEGVYQCMAESEVDGMQAAAQLVVINHAVPGILASSPPRGMTAVLVSTRFI 443 Query: 126 VLECLPP---RGSP-EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181 L P RGS +VY+ + G D+ V LV+ + R +Q + Sbjct: 444 RLSWRAPAESRGSVLHYSVYYVRVGSVRERRVDTLQ--VSELQLVVGELRPETGYSFQVV 501 Query: 182 ARNAAGTRESAIATLKIHIKPYL-ITGPE---DVVAQTGSSVTFQ 222 A N AG E + A L+I +P + + GP VVA + +SV+ Q Sbjct: 502 AVNQAGPGERS-APLRITTQPEVQVPGPVLNLHVVAISTTSVSLQ 545 Score = 44.0 bits (99), Expect = 0.025 Identities = 66/285 (23%), Positives = 107/285 (37%), Gaps = 26/285 (9%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPLGRVKVLDDGSLRL 259 P P V GS V C V D P R G + R +L +GSL + Sbjct: 45 PRFTLEPAGTVVVAGSPVVLSCTVDSDK-PIKFGTRKDGVLLDTVADERRHLLANGSLLI 103 Query: 260 -----DNVILADEGEYSCEAE-NSVGAV-SASGYLTVYDPPSINLSPNSVNVESGNVARF 312 + + D G Y CE + +G++ S +T+ P S S V G+ Sbjct: 104 RTGGHEELARIDSGRYQCEVTVHGLGSIISRPAAVTLIGEPRFVSSSLSTLVIQGDSVVL 163 Query: 313 TCTATGRPEPTMFWSVEGNRTIIFP-GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371 C A E T W N F G S + V +L + + K D Sbjct: 164 DCGA----EVTGLW----NEVRWFKEGRSITEDSQVMVLSSGDLL-LQNASKADG-GKYF 213 Query: 372 CSAVNYAGSSFVRG--KLTVTSD-DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428 C V + G +F L+V + + P ++ P + ++ + A C P P Sbjct: 214 CQLV-FGGRTFTNQGTNLSVLPEMESNRPCVVLRHPVDVSVRLGHTATLECVVAGFPAPS 272 Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473 + W G + + R +V G L + ++ + D+G YTC+ +++ Sbjct: 273 VHWT-RGTESVLSERFSVVAGGILRIDNVQQDDAGDYTCIIKAQN 316 >UniRef50_Q4RYE5 Cluster: Chromosome 2 SCAF14976, whole genome shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 2 SCAF14976, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 2095 Score = 162 bits (394), Expect = 5e-38 Identities = 195/772 (25%), Positives = 317/772 (41%), Gaps = 78/772 (10%) Query: 76 VHSDAGVYWCEATNSYGTARSRNATLHVAV---------LREEFRLEPESKQSAQGDT-V 125 V DAG Y+ +A N + + ++V + + P + G + V Sbjct: 14 VAPDAGRYYVQAVNDKNGDNKTSQPITLSVENVGGPADPIAPTIIIPPRNTSVVTGTSEV 73 Query: 126 VLECLP-PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC--IA 182 +EC+ R + ++ W+KNG L+ G S L I +DAG Y+C I Sbjct: 74 TMECVANARPLIKLSIVWRKNG-VLVSGGLSDF----SRRLTIFGPALSDAGYYECEAIL 128 Query: 183 RNAAGTRESAIATLKIHIKPYLITGPED-VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241 R+++ SA A L ++ P I PE + A+ V C+ G P PD++W + A Sbjct: 129 RSSSVPSVSAGAYLHVYEPPQFIKEPEKHITAEMEKVVDIPCQARGTPQPDIVWYKDALP 188 Query: 242 GN-MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLSP 299 + + + R +VL GSL+++ ++ D G + C A N G V + YL V P+I P Sbjct: 189 IDPVKMLRYRVLVGGSLQVNGLLPDDTGMFQCFARNVAGEVQTNTYLAVTSIAPNITAGP 248 Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359 + V G C +G P P + W +G R + + ++ T + G L I+ Sbjct: 249 SDSTVIDGMSIILHCETSGAPRPAITWQ-KGERVLASGSVQLPRF--TLLESGS--LLIS 303 Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419 + +D+ T C A N G L V + IT P +Q++ + A C Sbjct: 304 PSHISDA-GTYTCMASNSRGIDEAAADLVVWARTR-----ITTPPQDQSVIKGTKAFMTC 357 Query: 420 TAICTPEPIIA--WYFEGEAL-IQNHRRNVTN-DGTLVLKDLDKSDSGTYTCVASSRHGK 475 P + W EG A+ +Q R T+ DGTL + D GTYTC +S G Sbjct: 358 GVTHDPSVTVKHIWEKEGTAINVQAIPRMRTDPDGTLHISQTWSGDIGTYTCRVTSVGGN 417 Query: 476 YVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKP--ITHNVTDTSVTLSWSQNNKIGSS 533 S L V P+ P LP PP P + ++ L+W++ G+S Sbjct: 418 DSRSAHLRVSCPVPPYPR-------RQLPHPPENPTAVLSTSEKRAINLAWAKPFD-GNS 469 Query: 534 SILGYQVEVFSRETLSGNNTPRNSRGWVVIARRV--HQTHYVVKSLIPGITYMFIVRTEN 591 ++ Y +EV S NN P W ++ + T V LIP +Y F + N Sbjct: 470 PLIRYILEV------SENNAP-----WAILLASIEPESTEVTVNGLIPARSYQFRLCAVN 518 Query: 592 SHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKL 651 G S +D V++ ++ S +++ T+ + + P +S + Sbjct: 519 DVGKGQFSKETDRVSLPEEPPSAPPQNVIASGR-------TNQSIMIQWQPPPESHQNGI 571 Query: 652 MWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFY 711 L G + +R L + ++Y++K I S DV+ + L +T YE + F Sbjct: 572 ---------LRGYVVRYR-LTGLPVDYQLKNI-SSPDVTNLLLEDLIIWTNYEIEVAAFN 620 Query: 712 KKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVV 771 G S+ TL VP P N++ +N+TT+ W+ P Q NGI GY ++ Sbjct: 621 GAGLGAFSHKVTEWTLQGVPTIAPGNVQAEAVNSTTIRFTWTAPNPQFINGINQGYKLLT 680 Query: 772 NWLDVPANKSMVAINTTVHQATSL-IMTNLTSGVSYSVQIAAETIIGLGPFS 822 + +MV + + + +T L Y + T G GP S Sbjct: 681 WEPRKDKDVTMVIVRPNFQDSVHVGYVTGLKKFTEYYTSVLCFTTPGDGPRS 732 Score = 135 bits (327), Expect = 6e-30 Identities = 105/332 (31%), Positives = 147/332 (44%), Gaps = 22/332 (6%) Query: 11 APYIIEQPLDVTVARH-QPATLNCRAGGSP--SPAIRWYKGGVLVVSDTHRSILPAGGL- 66 AP II P + +V T+ C A P +I W K GVLV +GGL Sbjct: 54 APTIIIPPRNTSVVTGTSEVTMECVANARPLIKLSIVWRKNGVLV----------SGGLS 103 Query: 67 -FFLRAT-HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGD 123 F R T G SDAG Y CEA + S +A ++ V +F EPE +A+ + Sbjct: 104 DFSRRLTIFGPALSDAGYYECEAILRSSSVPSVSAGAYLHVYEPPQFIKEPEKHITAEME 163 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183 VV RG+P+P++ W K+ + R ++ GG+L + D G +QC AR Sbjct: 164 KVVDIPCQARGTPQPDIVWYKDALPIDPVKMLRYRVLVGGSLQVNGLLPDDTGMFQCFAR 223 Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR---RSAG 240 N AG ++ I P + GP D G S+ C G P P + W+ R Sbjct: 224 NVAGEVQTNTYLAVTSIAPNITAGPSDSTVIDGMSIILHCETSGAPRPAITWQKGERVLA 283 Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300 G++ L R +L+ GSL + ++D G Y+C A NS G A+ L V+ I P Sbjct: 284 SGSVQLPRFTLLESGSLLISPSHISDAGTYTCMASNSRGIDEAAADLVVWARTRITTPPQ 343 Query: 301 SVNVESGNVARFTCTATGRPEPTM--FWSVEG 330 +V G A TC T P T+ W EG Sbjct: 344 DQSVIKGTKAFMTCGVTHDPSVTVKHIWEKEG 375 Score = 68.1 bits (159), Expect = 1e-09 Identities = 47/149 (31%), Positives = 73/149 (48%), Gaps = 8/149 (5%) Query: 687 NDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQ-TLDDVPDGPPINIEMFILNT 745 N ++T L KY YE ++ F + +G+PS + + TLDDVP GPP+ I + T Sbjct: 1135 NATHSVQLTGLGKYVLYEIQVLAFTRMGDGRPSAPPILERTLDDVP-GPPVGILFPEVRT 1193 Query: 746 TTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMV-AINTTVHQATSLIMTNLTSGV 804 T+V L W P NGII Y + + +N + V +N + Q T +TNL Sbjct: 1194 TSVRLIWQSP--SEPNGIILAYQITYHHNSTNSNTATVDVLNPSARQYT---VTNLKPES 1248 Query: 805 SYSVQIAAETIIGLGPFSQKVYFNIDSRS 833 Y +I A+T G G ++ + + R+ Sbjct: 1249 VYVFRITAQTRKGWGEAAEALVVTTEKRA 1277 Score = 59.3 bits (137), Expect = 6e-07 Identities = 37/152 (24%), Positives = 67/152 (44%), Gaps = 3/152 (1%) Query: 673 NITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPD 732 +++ Y ++ + S+ + +E+ L K+ +YE + + EG S + + VP Sbjct: 1471 DLSAPYSIRNLTDSSLIQ-YELDKLSKHKRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPT 1529 Query: 733 GPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQA 792 PP N+ + T + + W PP + QNG I GY V W + + T Sbjct: 1530 APPQNVAIQSATATQLDVTWDPPPVDAQNGDIQGYKVYF-W-EFQRKNETERLRTLFMPE 1587 Query: 793 TSLIMTNLTSGVSYSVQIAAETIIGLGPFSQK 824 + + NLT +Y + +A G GP S++ Sbjct: 1588 GGVKLKNLTGYTTYMISVAPFNAAGDGPRSRR 1619 Score = 56.0 bits (129), Expect = 6e-06 Identities = 44/190 (23%), Positives = 90/190 (47%), Gaps = 13/190 (6%) Query: 639 IEATPIDSKTIKLMWEILNFYYLEGL-----FIYFRPLDNITIEYEMKTILHSNDVSGFE 693 ++A ++S TI+ W N ++ G+ + + P + + + + V Sbjct: 647 VQAEAVNSTTIRFTWTAPNPQFINGINQGYKLLTWEPRKDKDVTMVIVRPNFQDSVHVGY 706 Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753 +T L+K+T+Y ++ F +G S R A+T +D P G ++ + T++ + WS Sbjct: 707 VTGLKKFTEYYTSVLCFTTPGDGPRSPPRAARTHEDTP-GAVGHLSFTEILDTSLKVSWS 765 Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT-SLIMTNLTSGVSYSVQIAA 812 P +NG++TGY ++W + N++ + + T +T LT+ +Y++++A Sbjct: 766 EP--SEKNGVLTGYR--ISWEEY--NRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAG 819 Query: 813 ETIIGLGPFS 822 T G G S Sbjct: 820 MTSKGQGLLS 829 Score = 55.2 bits (127), Expect = 1e-05 Identities = 29/98 (29%), Positives = 50/98 (51%), Gaps = 2/98 (2%) Query: 728 DDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINT 787 ++ P PP N+ ++ ++W PP QNGI+ GY V +P + + I++ Sbjct: 536 EEPPSAPPQNVIASGRTNQSIMIQWQPPPESHQNGILRGYVVRYRLTGLPVDYQLKNISS 595 Query: 788 TVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825 T+L++ +L +Y +++AA GLG FS KV Sbjct: 596 P--DVTNLLLEDLIIWTNYEIEVAAFNGAGLGAFSHKV 631 Score = 47.6 bits (108), Expect = 0.002 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 4/107 (3%) Query: 721 SRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSP-PELQLQ-NGIITGYNVVVNWLDVPA 778 SR QTL PD P N+ + + T++ L+W P PE + N GY V + P Sbjct: 965 SRKIQTLPAPPDMAPANVTLRTASETSLWLRWMPLPEWEYNGNAEQVGYRVQYSRAGAP- 1023 Query: 779 NKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825 ++ ++ I T Q + +L + Y V++ A IG GP+SQ V Sbjct: 1024 SRPLIHI-ITDRQEREFTIEDLEEWMEYEVRVQALNGIGAGPWSQPV 1069 Score = 46.8 bits (106), Expect = 0.004 Identities = 45/171 (26%), Positives = 72/171 (42%), Gaps = 16/171 (9%) Query: 661 LEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN 720 ++G +YF ++T+ G ++ +L YT Y + PF +G S Sbjct: 1561 IQGYKVYFWEFQRKNETERLRTLFMPE--GGVKLKNLTGYTTYMISVAPFNAAGDGPRSR 1618 Query: 721 SRVAQTLDDV-PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWL----D 775 + V DG P I L TT+V++ W P NGII GY +V + Sbjct: 1619 RQEGAPSKQVCTDGVPSFIHFSELTTTSVNVSWGEP--AFPNGIIEGYRLVYEPCAPADE 1676 Query: 776 VPANKSMVAINTTVHQATS------LIMTNLTSGVSYSVQIAAETIIGLGP 820 P + S ++ TV L + +L GV+Y+ +I A+T + GP Sbjct: 1677 CPDSPSPPGVSKTVTVDMKGSGPLWLKLRDLADGVTYNFRIRAKTFM-YGP 1726 Score = 44.8 bits (101), Expect = 0.015 Identities = 37/129 (28%), Positives = 58/129 (44%), Gaps = 4/129 (3%) Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751 F I L ++ +YE + G S +T + VP P N+ F ++++ ++ Sbjct: 1039 FTIEDLEEWMEYEVRVQALNGIGAGPWSQPVRGRTRESVPSCGPTNVSAFATTSSSILVR 1098 Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT-SLIMTNLTSGVSYSVQI 810 W +NG+I GY VV D + S V T AT S+ +T L V Y +Q+ Sbjct: 1099 WLEVPDPDRNGLILGYKVVYKEKD---SDSAVHFWTVDGNATHSVQLTGLGKYVLYEIQV 1155 Query: 811 AAETIIGLG 819 A T +G G Sbjct: 1156 LAFTRMGDG 1164 Score = 39.1 bits (87), Expect = 0.72 Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 1/74 (1%) Query: 697 LRKYTKYEFFLIPFYKKFEGKPS-NSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPP 755 L+ +T Y+F + + + S S TL D PD P + + TT+V + W PP Sbjct: 1372 LKPFTSYQFRVKATNDIGDSEYSAESEAITTLQDAPDEVPAILSVTPHTTTSVLICWKPP 1431 Query: 756 ELQLQNGIITGYNV 769 + NGI+ G+ + Sbjct: 1432 SEEKINGILLGFRI 1445 >UniRef50_Q8IVU1 Cluster: Putative neuronal cell adhesion molecule precursor; n=30; Euteleostomi|Rep: Putative neuronal cell adhesion molecule precursor - Homo sapiens (Human) Length = 814 Score = 162 bits (394), Expect = 5e-38 Identities = 126/404 (31%), Positives = 178/404 (44%), Gaps = 29/404 (7%) Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67 S E + +E DV V QP L+CR G+P I W K GV + TH ++L G L Sbjct: 39 SAELAFAVEPSDDVAVPG-QPIVLDCRVEGTPPVRITWRKNGVELPESTHSTLLANGSLM 97 Query: 68 F--LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 R G SD G Y C A N +G SR A + A + +F + P++ +G Sbjct: 98 IRHFRLEPGGSPSDEGDYECVAQNRFGLVVSRKARIQAATM-SDFHVHPQATVGEEGGVA 156 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 +C G P+P + W+KN + D + R L+ G L I R D G + C+A N Sbjct: 157 RFQC-QIHGLPKPLITWEKNRVPIDTDNE-RYTLLPKGVLQITGLRAEDGGIFHCVASNI 214 Query: 186 AGTRESAIATLKI-------HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238 A R S A L + + +P ++ GPE++ + +C G+P P V W R Sbjct: 215 ASIRISHGARLTVSGSGSGAYKEPAILVGPENLTLTVHQTAVLECVATGNPRPIVSWSRL 274 Query: 239 AGGGNMPLG--RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV--SASGYLTVYDPPS 294 G P+G ++VL G+L + +V + G Y C A V +A G L V P Sbjct: 275 DG---RPIGVEGIQVLGTGNLIISDVTVQHSGVYVCAANRPGTRVRRTAQGRLVVQAPAE 331 Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354 P S++ +G A FTC A G P P + W G ++ PG H + T Sbjct: 332 FVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQ--VLGPG-----GHVRLKNNNST 384 Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398 LTI+ D C A N AGSS +LTV + P P Sbjct: 385 -LTISGIGPEDEA-IYQCVAENSAGSSQASARLTVLWAEGLPGP 426 Score = 134 bits (323), Expect = 2e-29 Identities = 134/518 (25%), Positives = 208/518 (40%), Gaps = 59/518 (11%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169 F +EP + G +VL+C G+P + W+KNG L + L+ G+L+I+ Sbjct: 44 FAVEPSDDVAVPGQPIVLDCRV-EGTPPVRITWRKNGVEL--PESTHSTLLANGSLMIRH 100 Query: 170 AR------QTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223 R +D G Y+C+A+N G S A ++ P+ V + G FQC Sbjct: 101 FRLEPGGSPSDEGDYECVAQNRFGLVVSRKARIQAATMSDFHVHPQATVGEEGGVARFQC 160 Query: 224 RVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG-AVS 282 ++ G P P + W ++ + R +L G L++ + D G + C A N +S Sbjct: 161 QIHGLPKPLITWEKNRVPIDTDNERYTLLPKGVLQITGLRAEDGGIFHCVASNIASIRIS 220 Query: 283 ASGYLTV-------YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII 335 LTV Y P+I + P ++ + A C ATG P P + WS R I Sbjct: 221 HGARLTVSGSGSGAYKEPAILVGPENLTLTVHQTAVLECVATGNPRPIVSWSRLDGRPIG 280 Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR---GKLTVTSD 392 G+ G L I+D S VC+A N G+ R G+L V Sbjct: 281 VEGIQ---------VLGTGNLIISDVTVQHS-GVYVCAA-NRPGTRVRRTAQGRLVV--- 326 Query: 393 DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGT 451 + P P + + P + A+F C A P P + W G+ L H R N+ T Sbjct: 327 --QAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQVLGPGGHVRLKNNNST 384 Query: 452 LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI 511 L + + D Y CVA + G S L V LPGPP Sbjct: 385 LTISGIGPEDEAIYQCVAENSAGSSQASARLTV-------------LWAEGLPGPPRNVR 431 Query: 512 THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTH 571 +V+ T V +SWS+ + I+GY + + R+ P +++ Q Sbjct: 432 AVSVSSTEVRVSWSE-PLANTKEIIGYVLHI--RKAAD----PPELEYQEAVSKSTFQ-- 482 Query: 572 YVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 ++V L P Y F ++ G S S + + T+G+ Sbjct: 483 HLVSDLEPSTAYSFYIKAYTPRGASSASVPTLASTLGE 520 Score = 107 bits (258), Expect = 1e-21 Identities = 88/289 (30%), Positives = 131/289 (45%), Gaps = 21/289 (7%) Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFFLRATHGRVHSDAGVYWCEA 87 A C+ G P P I W K V + +D R ++LP G L+ T R D G++ C A Sbjct: 156 ARFQCQIHGLPKPLITWEKNRVPIDTDNERYTLLPKG---VLQITGLRAE-DGGIFHCVA 211 Query: 88 TNSYGTARSRNATLHV------AVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVY 141 +N S A L V A + PE+ T VLEC+ G+P P V Sbjct: 212 SNIASIRISHGARLTVSGSGSGAYKEPAILVGPENLTLTVHQTAVLECVAT-GNPRPIVS 270 Query: 142 WKK-NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR--ESAIATLKI 198 W + +G+ + +G + ++ GNL+I D +G Y C A N GTR +A L + Sbjct: 271 WSRLDGRPIGVEG---IQVLGTGNLIISDVTVQHSGVYVCAA-NRPGTRVRRTAQGRLVV 326 Query: 199 HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-L 257 + P+ + G++ F C+ G+P P V W ++ G P G V++ ++ S L Sbjct: 327 QAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKN-GQVLGPGGHVRLKNNNSTL 385 Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306 + + DE Y C AENS G+ AS LTV + P +V S Sbjct: 386 TISGIGPEDEAIYQCVAENSAGSSQASARLTVLWAEGLPGPPRNVRAVS 434 Score = 38.7 bits (86), Expect = 0.96 Identities = 28/128 (21%), Positives = 55/128 (42%), Gaps = 9/128 (7%) Query: 639 IEATPIDSKTIKLMWE--ILNFYYLEGLFIYFRPL-DNITIEYEMKTILHSNDVSGFEIT 695 + A + S +++ W + N + G ++ R D +EY+ S ++ Sbjct: 430 VRAVSVSSTEVRVSWSEPLANTKEIIGYVLHIRKAADPPELEYQEAV---SKSTFQHLVS 486 Query: 696 SLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSP- 754 L T Y F++ + + S +A TL + P PP+++ +L ++++ L W P Sbjct: 487 DLEPSTAYSFYIKAYTPRGASSASVPTLASTLGEAPAPPPLSVR--VLGSSSLQLLWEPW 544 Query: 755 PELQLQNG 762 P L G Sbjct: 545 PRLAQHEG 552 >UniRef50_Q9UQ52 Cluster: Contactin-6 precursor; n=78; Euteleostomi|Rep: Contactin-6 precursor - Homo sapiens (Human) Length = 1028 Score = 162 bits (394), Expect = 5e-38 Identities = 137/490 (27%), Positives = 211/490 (43%), Gaps = 38/490 (7%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 + P+ + PLD++ + LNC A G PSP RW + G + GG + Sbjct: 30 QEPHDVIFPLDLSKSE---VILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAI 86 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLE 128 + H D G+Y C ATN GT SR A L A + E+F + S S +G VVL Sbjct: 87 NSPH--TDQDIGMYQCLATNLLGTILSRKAKLQFAYI-EDFETKTRSTVSVREGQGVVLL 143 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAG 187 C PP + + W N L D+R + + GNL I +D G Y C N Sbjct: 144 CGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEA 203 Query: 188 TRESAIATLKI---------HIKPYL-ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 R + +P + + PE + A SSV +C G+P+PD+ WRR Sbjct: 204 QRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRR 263 Query: 238 SAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296 G +P G+VK + L + N DEG Y C A N G A G L Y PP Sbjct: 264 -LDGSPLP-GKVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWE 321 Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356 + ++ + + C A+G+P P W G R + P + T + +T+L Sbjct: 322 QKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGER--LNPEERIQIENGTLI---ITML 376 Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT--LPIKSM 414 ++D+ C+A N + +L V + P + P + + + Sbjct: 377 NVSDS------GVYQCAAENKYQIIYANAELRVLAS----APDFSKSPVKKKSFVQVGGD 426 Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 V C P I+W E L Q+ R + DG+L + ++ +SD+G+YTC+A+++ G Sbjct: 427 IVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFG 486 Query: 475 KYVWSGALLV 484 +G+L+V Sbjct: 487 TAKNTGSLIV 496 Score = 106 bits (254), Expect = 4e-21 Identities = 164/729 (22%), Positives = 279/729 (38%), Gaps = 85/729 (11%) Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKK-NGQTLLFDGDSRMHLVDGGNLVIQDARQ 172 PE+ Q+A+ +V LEC G+P P++ W++ +G L G + + L I + +Q Sbjct: 234 PETIQAAKDSSVKLECFA-LGNPVPDISWRRLDGSPL--PGKVK-YSKSQAILEIPNFQQ 289 Query: 173 TDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232 D G Y+CIA N G R A L + P ++ ++ ++C+ G P P Sbjct: 290 EDEGFYECIASNLRG-RNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPW 348 Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-D 291 W ++ N P R+++ ++G+L + + ++D G Y C AEN + A+ L V Sbjct: 349 YTWLKNGERLN-PEERIQI-ENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLAS 406 Query: 292 PPSINLSPNSVN--VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349 P + SP V+ G C P + W G T+ R + Sbjct: 407 APDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWK-RGTETL------RQSKRIFLL 459 Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409 DG L I + ++D+ + C A N G++ G L V + +IT PS + Sbjct: 460 EDGS--LKIYNITRSDA-GSYTCIATNQFGTAKNTGSLIV-----KERTVITVPPSKMDV 511 Query: 410 PIKSMAVFPCTAICTP--EPIIAWYFEGEALIQN----HRRNVTND--GTLVLKDLDKSD 461 + V PC P E + W+F G+ + H + + G L+++++ Sbjct: 512 TVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHH 571 Query: 462 SGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVT 521 SG Y C + ++V P PGPP +++ T+ Sbjct: 572 SGKYLCTVQTTLESLSAVADIIVRGP----------------PGPPEDVQVEDISSTTSQ 615 Query: 522 LSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGI 581 LSW S +++F+ +T TP S GW +A V ++ G Sbjct: 616 LSWRAGPDNNSP------IQIFTIQT----RTPF-SVGWQAVA--------TVPEILNGK 656 Query: 582 TYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVEL-IE 640 TY V GLS V G NS+ G S R + + I Sbjct: 657 TYNATVV-----GLSPWVEYEFRVVAG---NSIGIGEPSEPSELLRTKASVPVVAPVNIH 708 Query: 641 ATPIDSKTIKLMWEILNFYYLEG----LFIYFRPLDNITIEYEMKTILHSNDVSGFEITS 696 + + WE + G I FRP+ + T E + + S+ + S Sbjct: 709 GGGGSRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRFV-YRNES 767 Query: 697 LRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPE 756 + + +E + + + EG S + + +D P P + + + + + W+ Sbjct: 768 IIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIA 827 Query: 757 LQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETII 816 G + GY V+ W D + +SM+ T+ +T L + Y + A Sbjct: 828 WNRNTGRVLGYEVLY-WTD-DSKESMIGKIRVSGNVTTKNITGLKANTIYFASVRAYNTA 885 Query: 817 GLGPFSQKV 825 G GP S V Sbjct: 886 GTGPSSPPV 894 Score = 99 bits (238), Expect = 4e-19 Identities = 80/282 (28%), Positives = 124/282 (43%), Gaps = 22/282 (7%) Query: 33 CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG 92 C+A G P+P W K G + + R + G L SD+GVY C A N Y Sbjct: 339 CKASGKPNPWYTWLKNGERL-NPEERIQIENGTLIITMLNV----SDSGVYQCAAENKYQ 393 Query: 93 TARSRNATLHVAVLREEFRLEPESKQS--AQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150 + NA L V +F P K+S G +V+ C P P + WK+ +TL Sbjct: 394 IIYA-NAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGC-KPNAFPRAAISWKRGTETLR 451 Query: 151 FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED 210 R+ L++ G+L I + ++DAG Y CIA N GT ++ +L + + + P Sbjct: 452 --QSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNT-GSLIVKERTVITVPPSK 508 Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-------RVKVLDDGSLRLDNVI 263 + G S+ C+V DP +V++ G + L R+ G L + N+ Sbjct: 509 MDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQ 568 Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305 L G+Y C + ++ ++SA + V PP P V VE Sbjct: 569 LHHSGKYLCTVQTTLESLSAVADIIVRGPPG---PPEDVQVE 607 Score = 91.5 bits (217), Expect = 1e-16 Identities = 78/318 (24%), Positives = 129/318 (40%), Gaps = 15/318 (4%) Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77 P + A+ L C A G+P P I W + L S + + L + + Sbjct: 234 PETIQAAKDSSVKLECFALGNPVPDISWRR---LDGSPLPGKVKYSKSQAILEIPNFQ-Q 289 Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137 D G Y C A+N G ++ + A E+ + ++ + D ++ EC G P Sbjct: 290 EDEGFYECIASNLRGRNLAKGQLIFYAP--PEWEQKIQNTHLSIYDNLLWEC-KASGKPN 346 Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197 P W KNG+ L + + R+ ++ G L+I +D+G YQC A N + Sbjct: 347 PWYTWLKNGERL--NPEERIQ-IENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRV 403 Query: 198 IHIKPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255 + P P + Q G + C+ P + W+R R+ +L+DG Sbjct: 404 LASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSK-RIFLLEDG 462 Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315 SL++ N+ +D G Y+C A N G +G L V + I + P+ ++V G C Sbjct: 463 SLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQ 522 Query: 316 ATGRP--EPTMFWSVEGN 331 + P E W G+ Sbjct: 523 VSHDPSIEVVFVWFFNGD 540 >UniRef50_O76518 Cluster: Hemicentin precursor; n=4; Eukaryota|Rep: Hemicentin precursor - Caenorhabditis elegans Length = 5198 Score = 161 bits (391), Expect = 1e-37 Identities = 145/510 (28%), Positives = 222/510 (43%), Gaps = 30/510 (5%) Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82 VA +QP + C G P P+I+W K G V D + I+ G + + T AG Sbjct: 3779 VAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDS---DHAGK 3835 Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW 142 + C A N G + L V ++ ++ A G+T+ L C G+P P + W Sbjct: 3836 WSCVAENDAGV-KELEMVLDVFT-PPVVSVKSDNPIKALGETITLFC-NASGNPYPQLKW 3892 Query: 143 KKNGQTLLFDG-DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201 K G +L+FD D + G L I ++TD G Y C A NAAGT E+++ ++ + + Sbjct: 3893 AKGG-SLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASV-SVDVLVP 3950 Query: 202 PYLITGPEDVVAQ--TGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LR 258 P + D+ + S+T QC G P+P + W + + V D + ++ Sbjct: 3951 PEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQ 4010 Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATG 318 ++NV L+D+G Y+C AEN G+ + + V P I+ + + V G +A C G Sbjct: 4011 INNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVIS-NGGTKQVIEGELAVIECLVEG 4069 Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378 P P + W GNR + G+ +Y V DG +LTI + DS +CSA N A Sbjct: 4070 YPAPQVSWLRNGNR--VETGVQGVRY----VTDG-RMLTIIEARSLDS-GIYLCSATNEA 4121 Query: 379 GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438 GS+ L V P IIT+ P T S PC P+PII+W G + Sbjct: 4122 GSAQQAYTLEVLVS----PKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDI 4177 Query: 439 IQNHR-RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRA 497 + DGTL ++ ++ Y C A + G V + + P I Sbjct: 4178 KDGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLE--FPVQTIVAPKISTSGN 4234 Query: 498 ADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527 ++ G T I + S SWS+N Sbjct: 4235 RYINGSEGTET-VIKCEIESESSEFSWSKN 4263 Score = 151 bits (367), Expect = 9e-35 Identities = 123/446 (27%), Positives = 189/446 (42%), Gaps = 29/446 (6%) Query: 33 CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG 92 C G+P P I WY G + ++ + A +R S +GVY C+ATNS G Sbjct: 1022 CVVSGTPPPIITWYLDGRPITPNSRDFTVTADNTLIVRKAD---KSYSGVYTCQATNSAG 1078 Query: 93 TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFD 152 + + ++ +S + D + G P+P + W LL D Sbjct: 1079 DNEQKTT---IRIMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITW------LLDD 1129 Query: 153 GDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDV 211 +V + G+L I + + G + C A+NAAG ++ TL +H P + ++ Sbjct: 1130 KPFTEGVVNEDGSLTIPNVNEAHRGTFTCHAQNAAG-NDTRTVTLTVHTTPTINAENQEK 1188 Query: 212 VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYS 271 +A + +C P P LW + L + +DG+L L NV L + G + Sbjct: 1189 IALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDGALVLQNVKLENTGVFV 1248 Query: 272 CEAENSVGAVSASGYLTVYDPPS-INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330 C+ N G S S LTV++ P I+ P V+V G C ATG PE W+ G Sbjct: 1249 CQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPEVIRTWNKNG 1308 Query: 331 NRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT 390 I M K+ D + L I + DKND N C N AG+S ++T Sbjct: 1309 ----IDLKMDEKKFSV----DNLGTLRIYEADKNDIGN-YNCVVTNEAGTS----QMTTH 1355 Query: 391 SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT-ND 449 D PP I+ + +N T + C +P + W+ G A+ + + V +D Sbjct: 1356 VDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRGIAIGTDTKGYVVESD 1415 Query: 450 GTLVLKDLDKSDSGTYTCVASSRHGK 475 GTLV++ D+ YTC AS+ GK Sbjct: 1416 GTLVIQSASVEDATIYTCKASNPAGK 1441 Score = 141 bits (342), Expect = 9e-32 Identities = 130/510 (25%), Positives = 225/510 (44%), Gaps = 45/510 (8%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 ++C+ G P P + W + G + I + +R +D G Y C A+N Sbjct: 3236 VHCQVTGRPVPYVTWKRNG--------KEIEQFNPVLHIR---NATRADEGKYSCIASNE 3284 Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150 GTA + L + F + +G++ +EC G P+P + W K G+ Sbjct: 3285 AGTAVAD--FLIDVFTKPTFETHETTFNIVEGESAKIECKID-GHPKPTISWLKGGRP-- 3339 Query: 151 FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI-TGPE 209 F+ D+ + G L+I A++ D G Y C+A N+ G E + ++ KPY+ T + Sbjct: 3340 FNMDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFK-VNVYTKPYIDETIDQ 3398 Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGSLRLDNVILADEG 268 A G + +C V G+P P V W+R G +P R ++++ L++++V D G Sbjct: 3399 TPKAVAGGEIILKCPVLGNPTPTVTWKR--GDDAVPNDSRHTIVNNYDLKINSVTTEDAG 3456 Query: 269 EYSCEAENSVGAVSASGYLTVYDPPS-INLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327 +YSC A N G ++ V P+ + N V + C T RP P++ W Sbjct: 3457 QYSCIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPLPSISW- 3515 Query: 328 VEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387 G++ + D+Y + DG + +TIN +D +C A N AG+S + L Sbjct: 3516 FRGDKPVYL----YDRYSISP--DG-SHITINKAKLSDG-GKYICRASNEAGTSDIDLIL 3567 Query: 388 TVTSDDDRPPPIITNGPSNQTLPIKSMAVF-PCTAICTPEPIIAWYFEGEALIQNHRRNV 446 + PP I + L I + ++ C P+P + W G + R + Sbjct: 3568 KILV----PPKIDKSNIIGNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDSRVI 3623 Query: 447 T--NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIH-----FFRAAD 499 N+ T ++++ +D G YTC A++R GK +L V SP +IH R D Sbjct: 3624 LAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGD 3683 Query: 500 VSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529 +L P + ++ D + +SW+++++ Sbjct: 3684 TITLTCP--IKLAEDIADQVMDVSWTKDSR 3711 Score = 138 bits (334), Expect = 9e-31 Identities = 122/451 (27%), Positives = 185/451 (41%), Gaps = 31/451 (6%) Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86 Q TL C A G P P +RW G + T I A F++ + + SD GVY C Sbjct: 3968 QSLTLQCLAQGKPVPQMRWTLNGTALTHSTP-GITVASDSTFIQINNVSL-SDKGVYTCY 4025 Query: 87 ATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146 A N G S N +V V++ +KQ +G+ V+ECL G P P V W +NG Sbjct: 4026 AENVAG---SDNLMYNVDVVQAPVISNGGTKQVIEGELAVIECLV-EGYPAPQVSWLRNG 4081 Query: 147 QTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT 206 + ++ DG L I +AR D+G Y C A N AG+ + A TL++ + P +IT Sbjct: 4082 NRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAY-TLEVLVSPKIIT 4140 Query: 207 G-PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA 265 P + +GS + C V G P P + W + + DG+L ++ A Sbjct: 4141 STPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEK---A 4197 Query: 266 DEGE--YSCEAENSVGAVSASGYLTVYDPPSINLSPNS-VNVESGNVARFTCTATGRPEP 322 +E Y C A+N GA + + P I+ S N +N G C Sbjct: 4198 EERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCEIESE-SS 4256 Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382 WS G P + + + + + +L+ +D+ + C+A N AG++ Sbjct: 4257 EFSWSKNG-----VPLLPSNNLIFSEDYKLIKILSTRLSDQGE----YSCTAANKAGNAT 4307 Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN- 441 + L V P I P Q + C A P+P I WY + E L Sbjct: 4308 QKTNLNV-----GVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTG 4362 Query: 442 -HRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471 T +++ + S +G YTC A + Sbjct: 4363 VDETATTKKKSVIFSSISPSQAGVYTCKAEN 4393 Score = 137 bits (331), Expect = 2e-30 Identities = 121/463 (26%), Positives = 195/463 (42%), Gaps = 28/463 (6%) Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88 A + C G P+P + W + G V + G L R D+G+Y C AT Sbjct: 4061 AVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRM-LTIIEAR-SLDSGIYLCSAT 4118 Query: 89 NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148 N G+A+ TL V V + P + G L C RG P+P + W NG Sbjct: 4119 NEAGSAQQAY-TLEVLVSPKIITSTPGVLTPSSGSKFSLPCAV-RGYPDPIISWTLNGND 4176 Query: 149 LLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG--TRESAIATLKIHIKPYLIT 206 + DG++ + G L I+ A + Y+C A+N AG T E + T+ + P + T Sbjct: 4177 IK-DGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTI---VAPKIST 4231 Query: 207 -GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL-RLDNVIL 264 G + G+ +C + + + W ++ G +P + +D L ++ + L Sbjct: 4232 SGNRYINGSEGTETVIKCEIESES-SEFSWSKN-GVPLLPSNNLIFSEDYKLIKILSTRL 4289 Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTM 324 +D+GEYSC A N G + L V P I P + V G+ C A+G P+P + Sbjct: 4290 SDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAI 4349 Query: 325 FWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR 384 W + N + G+ AT V +I+ + C A N+ S+ Sbjct: 4350 TW-YKDNELLTNTGVDET---ATTKKKSVIFSSISPSQAG----VYTCKAENWVASTEED 4401 Query: 385 GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR 444 L V PP ++ + T P + C A PEP+I+W + IQN+ + Sbjct: 4402 IDLIVMI----PPEVVPERMNVSTNP-RQTVFLSCNATGIPEPVISWMRDSNIAIQNNEK 4456 Query: 445 NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 TL ++++ D G Y C+A S G+ + + L+V+ P Sbjct: 4457 YQILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVNKP 4499 Score = 136 bits (329), Expect = 3e-30 Identities = 126/472 (26%), Positives = 200/472 (42%), Gaps = 23/472 (4%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 V + E+P I +V+V + A L+C + IRW + G V + + P G Sbjct: 514 VETRESPPEIFGVRNVSVPLGEAAFLHCSTRSAGEVEIRWTRYGATVFNGPNTERNPTNG 573 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 + H +DAGVY C A N+ G + +R L + + ++ P+ + V Sbjct: 574 TLKI---HHVTRADAGVYECMARNAGGMS-TRKMRLDI-MEPPSVKVTPQDVYFNMREGV 628 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 L C G P+P V+W G+ LL D ++ D L I+DA D G Y+C A + Sbjct: 629 NLSC-EAMGDPKPEVHWYFKGRHLLNDYKYQVGQ-DSKFLYIRDATHHDEGTYECRAMSQ 686 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVLWRRSAGGGNM 244 AG L + P + ++ G V+F+C+ + G P P + W ++ Sbjct: 687 AGQARDT-TDLMLATPPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIK 745 Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304 P +K+ ++G L + D G YSC EN G L+V P+I SP++V V Sbjct: 746 PDDYIKI-NEGQLHIMGAKDEDAGAYSCVGENMAGKDVQVANLSVGRVPTIIESPHTVRV 804 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 C A G P P + W +GN ++ ++ +Y T + DG L I D Sbjct: 805 NIERQVTLQCLAVGIPPPEIEWQ-KGN--VLLATLNNPRY--TQLADG--NLLITDAQIE 857 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC- 423 D + C A N G L VT P++ + P + L C + Sbjct: 858 D-QGQFTCIARNTYGQQSQSTTLMVTG---LVSPVLGHVPPEEQLIEGQDLTLSCVVVLG 913 Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHG 474 TP+P I W + + + + + G+L+ L+ + D G YTC+A S G Sbjct: 914 TPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEGKYTCIAVSPAG 965 Score = 135 bits (327), Expect = 6e-30 Identities = 129/474 (27%), Positives = 202/474 (42%), Gaps = 28/474 (5%) Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73 ++++ + T H TL+C A G P P I W+K G + + I+P G L + Sbjct: 2291 MLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGELNGNQLKI 2350 Query: 74 GRV-HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP 132 R+ DAG Y CEA NS G+ + + + E P +S Q + VV+ C P Sbjct: 2351 TRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQQNERVVISC-PV 2409 Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT--RE 190 P + W K G+ L D + +G L + R+TD+ +Y CIA N AGT R+ Sbjct: 2410 YARPPAKITWLKAGKPLQSDKFVKTS-ANGQKLYLFKLRETDSSKYTCIATNEAGTDKRD 2468 Query: 191 SAIATL--KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248 ++ L +P ++ + +G+ T C G P P + W + G P R Sbjct: 2469 FKVSMLVAPSFDEPNIV---RRITVNSGNPSTLHCPAKGSPSPTITWLKD-GNAIEPNDR 2524 Query: 249 VKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN-LSPNSVNVES 306 D G L++ +D+G Y+C A NSVG+ L V PP I+ +V V Sbjct: 2525 YVFFDAGRQLQISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIPPVIDGERREAVAVIE 2584 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 G + C + + W +G TI + D + + ++ K+DS Sbjct: 2585 GFSSELFCDSNS-TGVDVEWQKDG-LTINQDTLRGDSF--IQIPSSGKKMSFLSARKSDS 2640 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN---QTLPIKSMAVFPCTAIC 423 C N AG + KL + +D PP I++ S+ QT+ C Sbjct: 2641 -GRYTCIVRNPAGEA---RKLFDFAVND--PPSISDELSSANIQTIVPYYPVEINCVVSG 2694 Query: 424 TPEPIIAWYFEGEALIQNHRR-NVTNDG-TLVLKDLDKSDSGTYTCVASSRHGK 475 +P P + W F+ + L + +TN+G TL + +GTYTC A + GK Sbjct: 2695 SPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIVRSQVEHAGTYTCEAQNNVGK 2748 Score = 134 bits (323), Expect = 2e-29 Identities = 135/505 (26%), Positives = 215/505 (42%), Gaps = 57/505 (11%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGL 66 G P IIE P V V + TL C A G P P I W KG VL+ +++ + L G L Sbjct: 790 GRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEWQKGNVLLATLNNPRYTQLADGNL 849 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV-AVLREEFRLEPESKQSAQGDTV 125 T ++ D G + C A N+YG +S++ TL V ++ P +Q +G + Sbjct: 850 LI---TDAQI-EDQGQFTCIARNTYG-QQSQSTTLMVTGLVSPVLGHVPPEEQLIEGQDL 904 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARN 184 L C+ G+P+P++ W K+ + + + + + GG+L+ ++ D G+Y CIA + Sbjct: 905 TLSCVVVLGTPKPSIVWIKDDKPV--EEGPTIKIEGGGSLLRLRGGNPKDEGKYTCIAVS 962 Query: 185 AAGTRESAIATLKIHIKPYLITGPED-----------------VVAQT-----GSSVTFQ 222 AG I +++ KP + PE VV T G Sbjct: 963 PAGNSTLHI-NVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEGFAIP 1021 Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGR-VKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281 C V G P P + W G P R V D +L + + G Y+C+A NS G Sbjct: 1022 CVVSGTPPPIITWYLD-GRPITPNSRDFTVTADNTLIVRKADKSYSGVYTCQATNSAGDN 1080 Query: 282 SASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341 + + + P I+ +S N+ ++ C G P+P + W ++ Sbjct: 1081 EQKTTIRIMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLD------------ 1128 Query: 342 DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401 DK V + LTI + ++ R T C A N AG+ TVT P I Sbjct: 1129 DKPFTEGVVNEDGSLTIPNVNE-AHRGTFTCHAQNAAGND----TRTVTLTVHTTPTI-- 1181 Query: 402 NGPSNQTLPIKS-MAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDK 459 N + + + +++ V C A P P+ W +EGE + Q + DG LVL+++ Sbjct: 1182 NAENQEKIALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDGALVLQNVKL 1241 Query: 460 SDSGTYTCVASSRHGKYVWSGALLV 484 ++G + C S+ G+ S L V Sbjct: 1242 ENTGVFVCQVSNLAGEDSLSYTLTV 1266 Score = 133 bits (322), Expect = 2e-29 Identities = 139/501 (27%), Positives = 212/501 (42%), Gaps = 65/501 (12%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPAG 64 VT +P + P + + Q TL+C G+P P+I W K V I G Sbjct: 881 VTGLVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIKIEGGG 940 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVL---REEFRLEPES----- 116 L LR + + D G Y C A + G N+TLH+ V + EF +PE Sbjct: 941 SLLRLRGGNPK---DEGKYTCIAVSPAG-----NSTLHINVQLIKKPEFVYKPEGGIVFK 992 Query: 117 --------KQSA---------QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL 159 K A G+ + C+ G+P P + W +G+ + +SR Sbjct: 993 PTISGMDEKHVAVVNSTHDVLDGEGFAIPCVVS-GTPPPIITWYLDGRPIT--PNSRDFT 1049 Query: 160 VDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSS 218 V N L+++ A ++ +G Y C A N+AG E T++I P + G Sbjct: 1050 VTADNTLIVRKADKSYSGVYTCQATNSAGDNEQK-TTIRIMNTPMISPGQSSFNMVVDDL 1108 Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSV 278 T C V GDP P + W + P V +DGSL + NV A G ++C A+N+ Sbjct: 1109 FTIPCDVYGDPKPVITWLLD----DKPFTEGVVNEDGSLTIPNVNEAHRGTFTCHAQNAA 1164 Query: 279 GAVSASGYLTVYDPPSINL-SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR--TII 335 G + + LTV+ P+IN + + +++ ++ C A P P W+ EG + + + Sbjct: 1165 GNDTRTVTLTVHTTPTINAENQEKIALQNDDIV-LECPAKALPPPVRLWTYEGEKIDSQL 1223 Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395 P R+ DG VL K ++ VC N AG + LTV Sbjct: 1224 IPHTIRE--------DGALVL---QNVKLENTGVFVCQVSNLAGEDSLSYTLTV----HE 1268 Query: 396 PPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLV 453 P II+ P + +K + PC A PE I W G L + ++ +V N GTL Sbjct: 1269 KPKIISEVPGVVDV-VKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDEKKFSVDNLGTLR 1327 Query: 454 LKDLDKSDSGTYTCVASSRHG 474 + + DK+D G Y CV ++ G Sbjct: 1328 IYEADKNDIGNYNCVVTNEAG 1348 Score = 133 bits (321), Expect = 3e-29 Identities = 129/477 (27%), Positives = 195/477 (40%), Gaps = 40/477 (8%) Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62 D YV E P ++ + V + T+ C G+P P + W K G SD + Sbjct: 3118 DTYVEISEPPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKDGEPYTSDLLQFSTK 3177 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSA 120 L LR T +D G Y C ATN G +++ T V VL R+E E + Q Sbjct: 3178 LSYL-HLRET---TLADGGTYTCIATNKAGESQT---TTDVEVLVPP-RIEDEERVLQGK 3229 Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180 +G+T ++ C G P P V WK+NG+ + + + V L I++A + D G+Y C Sbjct: 3230 EGNTYMVHC-QVTGRPVPYVTWKRNGKEI-----EQFNPV----LHIRNATRADEGKYSC 3279 Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 IA N AGT A + + KP T G S +C++ G P P + W + G Sbjct: 3280 IASNEAGT-AVADFLIDVFTKPTFETHETTFNIVEGESAKIECKIDGHPKPTISWLK--G 3336 Query: 241 GGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS- 298 G + + + G +L + D G Y+C A NS G + VY P I+ + Sbjct: 3337 GRPFNMDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETI 3396 Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358 + +G C G P PT+ W G+ + P SR + +D L I Sbjct: 3397 DQTPKAVAGGEIILKCPVLGNPTPTVTWK-RGDDAV--PNDSR--HTIVNNYD----LKI 3447 Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418 N D+ C AVN AG+ V P + G + + Sbjct: 3448 NSVTTEDA-GQYSCIAVNEAGNLTTHYAAEVIG----KPTFVRKGGNLYEVIENDTITMD 3502 Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHG 474 C P P I+W+ + + R +++ DG+ + + SD G Y C AS+ G Sbjct: 3503 CGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAKLSDGGKYICRASNEAG 3559 Score = 128 bits (310), Expect = 7e-28 Identities = 129/484 (26%), Positives = 191/484 (39%), Gaps = 35/484 (7%) Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82 V + T++C P P+I W++G V SI P G + SD G Sbjct: 3493 VIENDTITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAK---LSDGGK 3549 Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLECLPPRGSPEPNVY 141 Y C A+N GT+ + L + V + + A T+ LEC P G P+P+V Sbjct: 3550 YICRASNEAGTS-DIDLILKILVPPKIDKSNIIGNPLAIVARTIYLEC-PISGIPQPDVI 3607 Query: 142 WKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200 W KNG + DSR+ L I++ + TD GRY C A N G + + Sbjct: 3608 WTKNGMDINMT-DSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSP 3666 Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVG-----GDPLPDVLWRRSAGGGNMPL-GRVKVLDD 254 + I G + + + G ++T C + D + DV W + + + L V + DD Sbjct: 3667 PEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDD 3726 Query: 255 G-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV--NVESGNVAR 311 G L + L + G Y+C A N G S + + PP I++S N V V Sbjct: 3727 GRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQPTI 3786 Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371 C TG P P++ W G D + V G VL I TD +D Sbjct: 3787 MRCAVTGHPFPSIKWLKNGKEV-------TDDENIRIVEQG-QVLQILRTD-SDHAGKWS 3837 Query: 372 CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431 C A N AG + L V + PP+++ N + C A P P + W Sbjct: 3838 CVAENDAGVKELEMVLDVFT-----PPVVSVKSDNPIKALGETITLFCNASGNPYPQLKW 3892 Query: 432 YFEGEALIQ--NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPIN 489 G + + R L + L K+D G YTC A + G ++ VD + Sbjct: 3893 AKGGSLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAG--TSEASVSVDVLVP 3950 Query: 490 PNIH 493 P I+ Sbjct: 3951 PEIN 3954 Score = 124 bits (299), Expect = 1e-26 Identities = 109/455 (23%), Positives = 187/455 (41%), Gaps = 20/455 (4%) Query: 22 TVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAG 81 T+ + P +NC GSP P + W + D+ L G L+ +V AG Sbjct: 2679 TIVPYYPVEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGET-LKIVRSQVEH-AG 2736 Query: 82 VYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVY 141 Y CEA N+ G AR ++ + V F E E + GDT++L C P +VY Sbjct: 2737 TYTCEAQNNVGKAR-KDFLVRVTA-PPHFEKEREEVVARVGDTMLLTCNAESSVPLSSVY 2794 Query: 142 WKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201 W + +++ + + + L + + + D G Y C A N AG + + I Sbjct: 2795 WHAHDESVQNGVITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIE-T 2853 Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDN 261 PY + + G +T C G P P +L+ + N V ++ +L +DN Sbjct: 2854 PYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLN-ESDEVDII-GSTLVIDN 2911 Query: 262 VILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPE 321 EG Y+C AEN G + V PP ++ +V V++G+ C Sbjct: 2912 PQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKEWINVEVQAGDPLTLECPIEDTSG 2971 Query: 322 PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381 + WS + + ++ + ++ + T D D + C AVN AG + Sbjct: 2972 VHITWSRQFGKDGQLDMRAQSSSDKSKLY--IMQATPEDAD------SYSCIAVNDAGGA 3023 Query: 382 FVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN 441 ++TV + PP I + S + + PC P P I+W+ +G+ +++ Sbjct: 3024 EAVFQVTVNT----PPKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFLDGKPILEM 3079 Query: 442 HRRNV-TNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 D +L + ++ + G YTCVA ++ G+ Sbjct: 3080 PGVTYKQGDLSLRIDNIKPNQEGRYTCVAENKAGR 3114 Score = 123 bits (297), Expect = 3e-26 Identities = 115/417 (27%), Positives = 170/417 (40%), Gaps = 27/417 (6%) Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138 DAG Y C ++ G + E F + S G+ L C R + E Sbjct: 493 DAGEYECRVISNNGNYSVKTRVETRESPPEIFGVRNVSVPL--GEAAFLHC-STRSAGEV 549 Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198 + W + G T+ F+G + G L I + DAG Y+C+ARNA G + L I Sbjct: 550 EIRWTRYGATV-FNGPNTERNPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMR-LDI 607 Query: 199 HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-L 257 P + P+DV V C GDP P+V W G + + +V D L Sbjct: 608 MEPPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFK-GRHLLNDYKYQVGQDSKFL 666 Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC-TA 316 + + DEG Y C A + G + L + PP + + N + V G+ F C T Sbjct: 667 YIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKMMVGRGDRVSFECKTI 726 Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376 G+P P + W G + +I P D Y + +G L I K++ C N Sbjct: 727 RGKPHPKIRWFKNG-KDLIKP----DDY--IKINEGQ--LHIMGA-KDEDAGAYSCVGEN 776 Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436 AG L+V R P II + P + I+ C A+ P P I W +G Sbjct: 777 MAGKDVQVANLSV----GRVPTIIES-PHTVRVNIERQVTLQCLAVGIPPPEIEWQ-KGN 830 Query: 437 ALI---QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490 L+ N R DG L++ D D G +TC+A + +G+ S L+V ++P Sbjct: 831 VLLATLNNPRYTQLADGNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVSP 887 Score = 121 bits (292), Expect = 1e-25 Identities = 109/470 (23%), Positives = 184/470 (39%), Gaps = 32/470 (6%) Query: 6 VTSGEAPYIIEQPLDVT-VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64 VT P I T + + CR G P P I W+ G ++ + Sbjct: 3029 VTVNTPPKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFLDGKPILEMP--GVTYKQ 3086 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124 G LR + + + + G Y C A N G A ++ + ++ + E + +G Sbjct: 3087 GDLSLRIDNIKPNQE-GRYTCVAENKAGRAE-QDTYVEISE-PPRVVMASEVMRVVEGRQ 3143 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 + C G+PEP V W K+G+ + D L +++ D G Y CIA N Sbjct: 3144 TTIRC-EVFGNPEPVVNWLKDGEP--YTSDLLQFSTKLSYLHLRETTLADGGTYTCIATN 3200 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 AG ++ +++ + P + + + G++ C+V G P+P V W+R+ Sbjct: 3201 KAGESQTT-TDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRN------ 3253 Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304 G+ + L + N ADEG+YSC A N G A + V+ P+ + N+ Sbjct: 3254 --GKEIEQFNPVLHIRNATRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNI 3311 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 G A+ C G P+PT+ W ++G R + D + D + +L D Sbjct: 3312 VEGESAKIECKIDGHPKPTISW-LKGGRP-----FNMDNIILSPRGDTLMILKAQRFD-- 3363 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424 C A N G S K+ V + P I + C + Sbjct: 3364 --GGLYTCVATNSYGDSEQDFKVNVYT----KPYIDETIDQTPKAVAGGEIILKCPVLGN 3417 Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 P P + W +A+ + R + N+ L + + D+G Y+C+A + G Sbjct: 3418 PTPTVTWKRGDDAVPNDSRHTIVNNYDLKINSVTTEDAGQYSCIAVNEAG 3467 Score = 120 bits (288), Expect = 3e-25 Identities = 121/466 (25%), Positives = 184/466 (39%), Gaps = 32/466 (6%) Query: 30 TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89 T+ C G P P I W +L ++ G + + + G + C A N Sbjct: 1110 TIPCDVYGDPKPVITW----LLDDKPFTEGVVNEDGSLTIPNVN---EAHRGTFTCHAQN 1162 Query: 90 SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149 + G +R TL V E + K + Q D +VLEC P + P P W G+ + Sbjct: 1163 AAGND-TRTVTLTVHTT-PTINAENQEKIALQNDDIVLEC-PAKALPPPVRLWTYEGEKI 1219 Query: 150 LFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208 D H + + G LV+Q+ + + G + C N AG +S TL +H KP +I+ Sbjct: 1220 --DSQLIPHTIREDGALVLQNVKLENTGVFVCQVSNLAG-EDSLSYTLTVHEKPKIISEV 1276 Query: 209 EDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267 VV G ++ CR G P W ++ M + V + G+LR+ D Sbjct: 1277 PGVVDVVKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDEKKFSVDNLGTLRIYEADKNDI 1336 Query: 268 GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE-SGNVARFTCTATGRPEPTMFW 326 G Y+C N G + ++ V +PP I S + N G+ C P ++ W Sbjct: 1337 GNYNCVVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTW 1396 Query: 327 SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386 G I G Y V + L I D+ C A N AG + + Sbjct: 1397 FRRG----IAIGTDTKGY----VVESDGTLVIQSASVEDA-TIYTCKASNPAGKAEANLQ 1447 Query: 387 LTV-TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN 445 +TV S D + P ++T ++ P C P P I+WY + LI + Sbjct: 1448 VTVIASPDIKDPDVVTQESIKESHPFS----LYCPVFSNPLPQISWYLNDKPLIDDKTSW 1503 Query: 446 VTNDGTLVLKDLDK--SDSGTYTCVASSRHGKYVWSGALLVDSPIN 489 T+D L +DSG Y CVA + G+ S + V P+N Sbjct: 1504 KTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLN 1549 Score = 120 bits (288), Expect = 3e-25 Identities = 121/472 (25%), Positives = 188/472 (39%), Gaps = 38/472 (8%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E PY ++Q + + TL+C A G+P P I + K G + I+ G + Sbjct: 2852 ETPYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDII--GSTLVI 2909 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 V G Y C A N G RS + +L + E + + GD + LEC Sbjct: 2910 DNPQKEVE---GRYTCIAENKAG--RSEKDMMVEVLLPPKLSKEWINVEVQAGDPLTLEC 2964 Query: 130 LPPRGSPEPNVYWKKN-GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188 P + ++ W + G+ D ++ D L I A DA Y CIA N AG Sbjct: 2965 -PIEDTSGVHITWSRQFGKDGQLDMRAQSSS-DKSKLYIMQATPEDADSYSCIAVNDAGG 3022 Query: 189 RESAIATLKIHIKPYLIT---GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 E A+ + ++ P + ++VA T ++ CR G P P++ W Sbjct: 3023 AE-AVFQVTVNTPPKIFGDSFSTTEIVADT--TLEIPCRTEGIPPPEISWFLDGKPILEM 3079 Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305 G D SLR+DN+ EG Y+C AEN G Y+ + +PP + ++ + V Sbjct: 3080 PGVTYKQGDLSLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEISEPPRVVMASEVMRVV 3139 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365 G C G PEP + W +G P S +T ++ L + +T D Sbjct: 3140 EGRQTTIRCEVFGNPEPVVNWLKDGE-----PYTSDLLQFSTK----LSYLHLRETTLAD 3190 Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425 T C A N AG S T T + PP I + + + C P Sbjct: 3191 G-GTYTCIATNKAGES-----QTTTDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRP 3244 Query: 426 EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477 P + W G+ + Q + L +++ ++D G Y+C+AS+ G V Sbjct: 3245 VPYVTWKRNGKEIEQ-------FNPVLHIRNATRADEGKYSCIASNEAGTAV 3289 Score = 118 bits (285), Expect = 7e-25 Identities = 128/483 (26%), Positives = 203/483 (42%), Gaps = 61/483 (12%) Query: 23 VARHQPATLNCRA-GGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAG 81 V R + C+ G P P IRW+K G ++ + G L + G DAG Sbjct: 713 VGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIKINEGQLHIM----GAKDEDAG 768 Query: 82 VYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSPEPNV 140 Y C N G +++V R +E P + + V L+CL G P P + Sbjct: 769 AYSCVGENMAGKDVQ---VANLSVGRVPTIIESPHTVRVNIERQVTLQCLAV-GIPPPEI 824 Query: 141 YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH- 199 W+K L + R + GNL+I DA+ D G++ CIARN G ++S TL + Sbjct: 825 EWQKGNVLLATLNNPRYTQLADGNLLITDAQIEDQGQFTCIARNTYG-QQSQSTTLMVTG 883 Query: 200 -IKPYLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGNMPLGR---VKVLDD 254 + P L P + G +T C V G P P ++W + + P+ +K+ Sbjct: 884 LVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKD----DKPVEEGPTIKIEGG 939 Query: 255 GS-LRLDNVILADEGEYSCEAENSVG--AVSASGYLT-----VYDPP-SINLSPNSVNVE 305 GS LRL DEG+Y+C A + G + + L VY P I P ++ Sbjct: 940 GSLLRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMD 999 Query: 306 SGNVA--------------RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 +VA C +G P P + W ++G I P SRD + TA Sbjct: 1000 EKHVAVVNSTHDVLDGEGFAIPCVVSGTPPPIITWYLDGRP--ITPN-SRD-FTVTA--- 1052 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411 L + DK+ S C A N AG + + + + + P+I+ G S+ + + Sbjct: 1053 -DNTLIVRKADKSYS-GVYTCQATNSAGDNEQKTTIRIMN-----TPMISPGQSSFNMVV 1105 Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471 + PC P+P+I W + + + V DG+L + +++++ GT+TC A + Sbjct: 1106 DDLFTIPCDVYGDPKPVITWLLDDKPFTEG---VVNEDGSLTIPNVNEAHRGTFTCHAQN 1162 Query: 472 RHG 474 G Sbjct: 1163 AAG 1165 Score = 116 bits (278), Expect = 5e-24 Identities = 125/466 (26%), Positives = 191/466 (40%), Gaps = 28/466 (6%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 ++TV + TL C + I W G +++T AGG F L + D Sbjct: 2015 ELTVNLTRSITLECDVDDAIGVGISWTVNGKPFLAETDGVQTLAGGRF-LHIVSAKT-DD 2072 Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139 G Y C TN G A ++ L V V E + +++VL C G P P Sbjct: 2073 HGSYACTVTNEAGVA-TKTFNLFVQVPPTIVN-EGGEYTVIENNSLVLPC-EVTGKPNPV 2129 Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199 V W K+G+ + D S L +G I A G Y C+A+N GT E + + I Sbjct: 2130 VTWTKDGRPV-GDLKSVQVLSEGQQFKIVHAEIAHKGSYICMAKNDVGTAEISF-DVDII 2187 Query: 200 IKPYLITGPEDVV-AQTGSSVTFQCRVGGDP--LPDVLWRRSAGGGNMPLGRVKVL---D 253 +P + G +++V A G ++ F+C + D ++W R+ ++ ++ + Sbjct: 2188 TRPMIQKGIKNIVTAIKGGALPFKCPIDDDKNFKGQIIWLRNYQPIDLEAEDARITRLSN 2247 Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI---NLSPNSVNVESGNVA 310 D L + NV DEG+YSC +N G S TV PP+I + N VE V Sbjct: 2248 DRRLTILNVTENDEGQYSCRVKNDAGENSFDFKATVLVPPTIIMLDKDKNKTAVEHSTVT 2307 Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370 +C ATG+PEP + W +G I ++ + + + + I + D Sbjct: 2308 -LSCPATGKPEPDITWFKDG-EAIHIENIADIIPNGELNGNQLKITRIKEGD----AGKY 2361 Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG-PSNQTLPIKSMAVFPCTAICTPEPII 429 C A N AGS + V + P I +G PS+ V C P I Sbjct: 2362 TCEADNSAGSVEQDVNVNVIT----IPKIEKDGIPSDYESQQNERVVISCPVYARPPAKI 2417 Query: 430 AWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 W G+ L + N L L L ++DS YTC+A++ G Sbjct: 2418 TWLKAGKPLQSDKFVKTSANGQKLYLFKLRETDSSKYTCIATNEAG 2463 Score = 110 bits (264), Expect = 3e-22 Identities = 114/460 (24%), Positives = 188/460 (40%), Gaps = 45/460 (9%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 L C SP ++ W++ G+ + +DT ++ + G +++ DA +Y C+A+N Sbjct: 1382 LKCYVEASPPASVTWFRRGIAIGTDTKGYVVESDGTLVIQSASVE---DATIYTCKASNP 1438 Query: 91 YGTARSRNATLHVAVLREEFRLEPE---SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147 G A A L V V+ +P+ + + L C P +P P + W N + Sbjct: 1439 AGKAE---ANLQVTVIASPDIKDPDVVTQESIKESHPFSLYC-PVFSNPLPQISWYLNDK 1494 Query: 148 TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT-----RESAIATLKIHIKP 202 L+ D S D L + A+ TD+G Y+C+ARNAAG + I L + Sbjct: 1495 PLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLNLDESK 1554 Query: 203 YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW---RRSAGGGNMPLGRVKVLDDGSLRL 259 Y + V A+ G VT C V G P+P + W G G D +L Sbjct: 1555 Y----KKKVFAKEGEEVTLGCPVSGFPVPQINWVVDGTVVEPGKKYKGATLSNDGLTLHF 1610 Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC-TATG 318 D+V + EG Y C A++ + L+V P + N + V G +C T Sbjct: 1611 DSVSVKQEGNYHCVAQSKGNILDIDVELSVLAVPIVGEDDN-LEVFLGKDISLSCDLQTE 1669 Query: 319 RPEPTMF-WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377 + T F WS+ G+ + D+ + L I D K ++ +C N Sbjct: 1670 SDDKTTFVWSINGSES--------DRPDNVQIPSDGHRLYITDA-KPENNGKYMCRVTNS 1720 Query: 378 AGSSFVRGKLTVTSDDDRPPPIITN-GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436 AG + + T+T D PP + +NQ L + + C P+P + W +G Sbjct: 1721 AG----KAERTLTLDVLEPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKIDGN 1776 Query: 437 ALIQNHRRNVTNDGTLVLKDLDK--SDSGTYTCVASSRHG 474 + ++ D +L L ++K S +C A ++ G Sbjct: 1777 DV----DKSWLFDESLSLLRIEKLTGKSAQISCTAENKAG 1812 Score = 104 bits (249), Expect = 2e-20 Identities = 98/387 (25%), Positives = 144/387 (37%), Gaps = 20/387 (5%) Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73 I P +T + +L C G P P I W G + + + A G + Sbjct: 4139 ITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKAE 4198 Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133 R H +Y C A N G A + + V + ++G V++C Sbjct: 4199 ER-HL---IYECTAKNDAG-ADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCEIES 4253 Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193 S E + W KNG LL ++ + D + I R +D G Y C A N AG Sbjct: 4254 ESSEFS--WSKNGVPLL-PSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQK- 4309 Query: 194 ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVL 252 L + + P ++ P V G VT C G P P + W + N + Sbjct: 4310 TNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATT 4369 Query: 253 DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARF 312 S+ ++ + G Y+C+AEN V + L V PP + +V+ Sbjct: 4370 KKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFL 4429 Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372 +C ATG PEP + W + N I + +KY T L I + +D C Sbjct: 4430 SCNATGIPEPVISWMRDSNIAI----QNNEKYQILG-----TTLAIRNVLPDDD-GFYHC 4479 Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPI 399 A + AG KL V DRP PI Sbjct: 4480 IAKSDAGQKIATRKLIVNKPSDRPAPI 4506 Score = 98.3 bits (234), Expect = 1e-18 Identities = 109/363 (30%), Positives = 152/363 (41%), Gaps = 31/363 (8%) Query: 6 VTSGEAPYII-EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPA 63 +T E P II E P V V + + CRA G P W K G+ L + + S+ Sbjct: 1264 LTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDEKKFSVDNL 1323 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL--EPESKQSAQ 121 G L A +D G Y C TN GT++ T HV V L + + Sbjct: 1324 GTLRIYEAD----KNDIGNYNCVVTNEAGTSQ---MTTHVDVQEPPIILPSTQTNNTAVV 1376 Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQC 180 GD V L+C SP +V W + G + D++ ++V+ G LVIQ A DA Y C Sbjct: 1377 GDRVELKCY-VEASPPASVTWFRRG--IAIGTDTKGYVVESDGTLVIQSASVEDATIYTC 1433 Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQ----TGSSVTFQCRVGGDPLPDVLWR 236 A N AG E A L++ + DVV Q + C V +PLP + W Sbjct: 1434 KASNPAGKAE---ANLQVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQISWY 1490 Query: 237 RSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295 + K DD L + + D G Y C A N+ G S S + V P ++ Sbjct: 1491 LNDKPLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLNL 1550 Query: 296 NLS--PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH-ATAVFDG 352 + S V + G C +G P P + W V+G T++ PG KY AT DG Sbjct: 1551 DESKYKKKVFAKEGEEVTLGCPVSGFPVPQINWVVDG--TVVEPG---KKYKGATLSNDG 1605 Query: 353 VTV 355 +T+ Sbjct: 1606 LTL 1608 Score = 97.5 bits (232), Expect = 2e-18 Identities = 87/342 (25%), Positives = 139/342 (40%), Gaps = 23/342 (6%) Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC--IARNAAGTRESAIATLK 197 +YW K G+ ++ G H D I + DAG Y+C I+ N + ++ + T + Sbjct: 460 IYWVKTGEDII-GGPLFYHNTDTSVWTIPELSLKDAGEYECRVISNNGNYSVKTRVETRE 518 Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR-SAGGGNMPLGRVKVLDDGS 256 P I G +V G + C ++ W R A N P + +G+ Sbjct: 519 ---SPPEIFGVRNVSVPLGEAAFLHCSTRSAGEVEIRWTRYGATVFNGP-NTERNPTNGT 574 Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316 L++ +V AD G Y C A N+ G + L + +PPS+ ++P V +C A Sbjct: 575 LKIHHVTRADAGVYECMARNAGGMSTRKMRLDIMEPPSVKVTPQDVYFNMREGVNLSCEA 634 Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376 G P+P + W +G ++ KY V L I D +D T C A++ Sbjct: 635 MGDPKPEVHWYFKGRHL-----LNDYKYQ---VGQDSKFLYIRDATHHD-EGTYECRAMS 685 Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI-CTPEPIIAWYFEG 435 AG + L + + PP + + + F C I P P I W+ G Sbjct: 686 QAGQARDTTDLMLAT-----PPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKIRWFKNG 740 Query: 436 EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477 + LI+ N+G L + D+G Y+CV + GK V Sbjct: 741 KDLIKPDDYIKINEGQLHIMGAKDEDAGAYSCVGENMAGKDV 782 Score = 93.5 bits (222), Expect = 3e-17 Identities = 106/471 (22%), Positives = 181/471 (38%), Gaps = 34/471 (7%) Query: 10 EAPYIIEQPLDVT--VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67 E P +E + + + P L C+ G+P P + W G +D +S L L Sbjct: 1734 EPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKIDG----NDVDKSWLFDESLS 1789 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ-SAQGDTVV 126 LR ++ + C A N GTA SR+ + + F+ E + + + +T+ Sbjct: 1790 LLRIE--KLTGKSAQISCTAENKAGTA-SRDFFIQ-NIAAPTFKNEGDQETIFRESETIT 1845 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186 L+C P + + W K G L + D+ + +D L I +A + Y C+A N A Sbjct: 1846 LDC--PVSLGDFQITWMKQGLPLT-ENDA-IFTLDNTRLTILNANRDHEDIYTCVANNTA 1901 Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 G + S + + + P + + G + C G+P P W G++P Sbjct: 1902 G-QVSKDFDVVVQVLPKIKNAVVTLEINEGEEIILTCDAEGNPTPTAKW--DFNQGDLPK 1958 Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNV 304 V V ++ ++ ++NV G Y C A N VG + + V P L+ + + V Sbjct: 1959 EAVFVNNNHTVVVNNVTKYHTGVYKCYATNKVGQAVKTINVHVRTKPRFESGLTESELTV 2018 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 C + W+V G P ++ + G L I K Sbjct: 2019 NLTRSITLECDVDDAIGVGISWTVNGK-----PFLA--ETDGVQTLAGGRFLHIVSA-KT 2070 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424 D + C+ N AG + L V + PP I N T+ + V PC Sbjct: 2071 DDHGSYACTVTNEAGVATKTFNLFV-----QVPPTIVNEGGEYTVIENNSLVLPCEVTGK 2125 Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474 P P++ W +G + V ++G + + + G+Y C+A + G Sbjct: 2126 PNPVVTWTKDGRPVGDLKSVQVLSEGQQFKIVHAEIAHKGSYICMAKNDVG 2176 Score = 92.7 bits (220), Expect = 6e-17 Identities = 114/453 (25%), Positives = 176/453 (38%), Gaps = 45/453 (9%) Query: 38 SPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97 S S W K GV ++ + L + +T SD G Y C A N G A ++ Sbjct: 4253 SESSEFSWSKNGVPLLPSNNLIFSEDYKLIKILSTR---LSDQGEYSCTAANKAGNA-TQ 4308 Query: 98 NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM 157 L+V V + P ++ +GD V L C G P+P + W K+ + L G Sbjct: 4309 KTNLNVGVAPKIME-RPRTQVVHKGDQVTLWC-EASGVPQPAITWYKDNELLTNTGVDET 4366 Query: 158 HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGS 217 +++ + AG Y C A N + E I L + I P ++ +V Sbjct: 4367 ATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDI-DLIVMIPPEVVPERMNVSTNPRQ 4425 Query: 218 SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENS 277 +V C G P P + W R + + ++L +L + NV+ D+G Y C A++ Sbjct: 4426 TVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGT-TLAIRNVLPDDDGFYHCIAKSD 4484 Query: 278 VGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337 G A+ L V P P + VE C G+P+ T + +I Sbjct: 4485 AGQKIATRKLIVNKPSD---RPAPIWVE--------CDEKGKPKKTEY--------MIDR 4525 Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397 G + D D +L D + + +I Y R TV P Sbjct: 4526 GDTPD--------DNPQLLPWKDVEDSSLNGSIA-----YRCMPGPRSSRTVLLH--AAP 4570 Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL 457 I P N T I ++ C+A P P I W +G+ LI++ + + V + Sbjct: 4571 QFIVK-PKNTTAAIGAIVELRCSAAGPPHPTITWAKDGK-LIEDSKFEIAYSHLKVTLN- 4627 Query: 458 DKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490 SDSG YTC+A + G S + VD+ I P Sbjct: 4628 STSDSGEYTCMAQNSVGSSTVSAFINVDNNILP 4660 Score = 89.8 bits (213), Expect = 4e-16 Identities = 124/473 (26%), Positives = 194/473 (41%), Gaps = 62/473 (13%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD--THRSILPAGGL 66 G AP I+E+P V + TL C A G P PAI WYK L+ + + + Sbjct: 4315 GVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATTKKKSV 4374 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126 F + S AGVY C+A N + + + L + ++ E E + + TV Sbjct: 4375 IFSSIS----PSQAGVYTCKAEN-WVASTEEDIDL-IVMIPPEVVPERMNVSTNPRQTVF 4428 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186 L C G PEP + W ++ + + + + + G L I++ D G Y CIA++ A Sbjct: 4429 LSC-NATGIPEPVISWMRDSNIAIQNNEK--YQILGTTLAIRNVLPDDDGFYHCIAKSDA 4485 Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD--VLWRRSAGGGNM 244 G + IAT K+ ++ P D A + +C G P ++ R N Sbjct: 4486 GQK---IATRKL-----IVNKPSDRPA----PIWVECDEKGKPKKTEYMIDRGDTPDDNP 4533 Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304 L K ++D SL N +A Y C + +S + ++ P + P + Sbjct: 4534 QLLPWKDVEDSSL---NGSIA----YRC-----MPGPRSSRTVLLHAAPQFIVKPKNTTA 4581 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 G + C+A G P PT+ W+ +G +I Y V T+N T + Sbjct: 4582 AIGAIVELRCSAAGPPHPTITWAKDGK--LIEDSKFEIAYSHLKV-------TLNST--S 4630 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC-TAIC 423 DS C A N GSS V + V ++ P P SNQ K++AV C Sbjct: 4631 DS-GEYTCMAQNSVGSSTVSAFINV-DNNILPTP---KPSSNQ----KNVAVITCYERNQ 4681 Query: 424 TPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKD---LDKSDSGTYTCVASSR 472 + W + G + +N + N+G+LV+ D L + D YTC +R Sbjct: 4682 AYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNR 4734 Score = 88.2 bits (209), Expect = 1e-15 Identities = 88/309 (28%), Positives = 130/309 (42%), Gaps = 26/309 (8%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 AP I +P + T A L C A G P P I W K G L + D+ I + L Sbjct: 4569 APQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKL-IEDSKFEIAYSHLKVTLN 4627 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130 +T SD+G Y C A NS G ++T+ + + L S Q + V+ C Sbjct: 4628 ST-----SDSGEYTCMAQNSVG-----SSTVSAFINVDNNILPTPKPSSNQKNVAVITCY 4677 Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA---RQTDAGRYQCIARNAAG 187 + + W+ NG + + +H ++ G+LVI D ++ D Y C RN Sbjct: 4678 ERNQAYSRGLTWEYNGVPMP-KNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRN--- 4733 Query: 188 TRESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPL-PDVLWRRSAGGGNM 244 R +I L + P + T + V G SV C V DPL V+W ++ + Sbjct: 4734 RRRHSIPHLTSAFEGVPEVKT-IDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKN-DQKML 4791 Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP---PSINLSPNS 301 + VL + SL L NV DEG Y C A NS+G L VY+ P + Sbjct: 4792 DDDAIYVLPNNSLVLLNVEKYDEGVYKCVASNSIGKAFDDTQLNVYEGDFLPLTGFEGSG 4851 Query: 302 VNVESGNVA 310 +N++ + A Sbjct: 4852 INIDDSSNA 4860 Score = 82.2 bits (194), Expect = 8e-14 Identities = 109/467 (23%), Positives = 178/467 (38%), Gaps = 52/467 (11%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P ++ + ++V+ Q L+C A G P P I W + + + + + + L A Sbjct: 4410 PEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTL----A 4465 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131 + D G Y C A + G + AT + V + R P + +EC Sbjct: 4466 IRNVLPDDDGFYHCIAKSDAG---QKIATRKLIVNKPSDRPAP----------IWVEC-D 4511 Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191 +G P+ Y G T D L+ + ++D+ + Y+C+ G R S Sbjct: 4512 EKGKPKKTEYMIDRGDT----PDDNPQLLPWKD--VEDSSLNGSIAYRCMP----GPRSS 4561 Query: 192 AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251 T+ +H P I P++ A G+ V +C G P P + W A G + Sbjct: 4562 R--TVLLHAAPQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITW---AKDGKLIEDSKFE 4616 Query: 252 LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVAR 311 + L++ +D GEY+C A+NSVG+ + S ++ V + P+S NVA Sbjct: 4617 IAYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSS---NQKNVAV 4673 Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD--KNDSRNT 369 TC + + T + G+ K A F L I DT K Sbjct: 4674 ITCYERNQ-------AYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLEL 4726 Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP-EPI 428 C N S +TS + P + T + V C P Sbjct: 4727 YTCKVRNRRRHSIPH----LTSAFEGVPEVKT--IDKVEVNNGDSVVLDCEVTSDPLTTH 4780 Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 + W + ++ + V + +LVL +++K D G Y CVAS+ GK Sbjct: 4781 VVWTKNDQKMLDDDAIYVLPNNSLVLLNVEKYDEGVYKCVASNSIGK 4827 Score = 77.8 bits (183), Expect = 2e-12 Identities = 79/334 (23%), Positives = 134/334 (40%), Gaps = 20/334 (5%) Query: 3 DDYVTSGEAPYIIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL 61 D ++ + AP + T+ R + TL+C I W K G+ + + L Sbjct: 1817 DFFIQNIAAPTFKNEGDQETIFRESETITLDCPVSLGDFQ-ITWMKQGLPLTENDAIFTL 1875 Query: 62 PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121 L L A R H D +Y C A N+ G S++ + V VL + + + + + Sbjct: 1876 DNTRLTILNAN--RDHED--IYTCVANNTAGQV-SKDFDVVVQVL-PKIKNAVVTLEINE 1929 Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181 G+ ++L C G+P P W N L + + + + +V+ + + G Y+C Sbjct: 1930 GEEIILTC-DAEGNPTPTAKWDFNQGDLPKEA---VFVNNNHTVVVNNVTKYHTGVYKCY 1985 Query: 182 ARNAAGTRESAIATLKIHI--KPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 A N G A+ T+ +H+ KP +G ++ S+T +C V + W Sbjct: 1986 ATNKVG---QAVKTINVHVRTKPRFESGLTESELTVNLTRSITLECDVDDAIGVGISWTV 2042 Query: 238 SAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296 + V+ L G L + + D G Y+C N G + + L V PP+I Sbjct: 2043 NGKPFLAETDGVQTLAGGRFLHIVSAKTDDHGSYACTVTNEAGVATKTFNLFVQVPPTIV 2102 Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330 V N C TG+P P + W+ +G Sbjct: 2103 NEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDG 2136 Score = 76.6 bits (180), Expect = 4e-12 Identities = 120/515 (23%), Positives = 196/515 (38%), Gaps = 46/515 (8%) Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85 + TL C G P P I W G +V ++ + L V + G Y C Sbjct: 1565 EEVTLGCPVSGFPVPQINWVVDGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQE-GNYHC 1623 Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC-LPPRGSPEPNVYWKK 144 A + + + ++VL E ++ + G + L C L + W Sbjct: 1624 VAQSK---GNILDIDVELSVLAVPIVGEDDNLEVFLGKDISLSCDLQTESDDKTTFVWSI 1680 Query: 145 NGQTLLFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY 203 NG D + + DG L I DA+ + G+Y C N+AG E + TL + ++P Sbjct: 1681 NGSE--SDRPDNVQIPSDGHRLYITDAKPENNGKYMCRVTNSAGKAERTL-TLDV-LEPP 1736 Query: 204 LITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG-SLRL 259 + P Q + + QC+V G+P P V+W+ GN + + + D+ SL Sbjct: 1737 VFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKID---GN-DVDKSWLFDESLSLLR 1792 Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV--ESGNVARFTCTAT 317 + + SC AEN G S ++ P+ + + ES + + Sbjct: 1793 IEKLTGKSAQISCTAENKAGTASRDFFIQNIAAPTFKNEGDQETIFRESETITLDCPVSL 1852 Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377 G + T W +G P D A D T LTI + ++ D + C A N Sbjct: 1853 GDFQIT--WMKQG-----LPLTEND---AIFTLDN-TRLTILNANR-DHEDIYTCVANNT 1900 Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437 AG + V + P I N + + C A P P W F + Sbjct: 1901 AGQVSKDFDVVV-----QVLPKIKNAVVTLEINEGEEIILTCDAEGNPTPTAKWDF-NQG 1954 Query: 438 LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRA 497 + V N+ T+V+ ++ K +G Y C A+++ G+ V + ++ + F Sbjct: 1955 DLPKEAVFVNNNHTVVVNNVTKYHTGVYKCYATNKVGQAVKT----INVHVRTKPRFESG 2010 Query: 498 ADVSSLPGPPTKPIT--HNVTDT-SVTLSWSQNNK 529 S L T+ IT +V D V +SW+ N K Sbjct: 2011 LTESELTVNLTRSITLECDVDDAIGVGISWTVNGK 2045 >UniRef50_UPI00005BDC8C Cluster: PREDICTED: similar to hemicentin; n=1; Bos taurus|Rep: PREDICTED: similar to hemicentin - Bos taurus Length = 2756 Score = 161 bits (390), Expect = 1e-37 Identities = 152/538 (28%), Positives = 230/538 (42%), Gaps = 31/538 (5%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 V +G P ++ P +VTV+ + A L+C + W + ++ + T R A Sbjct: 962 VVTGPPPQLVPVP-NVTVSPGETAILSCLVLSEAPYNLTWVRDWRVLSASTGRVTQLADL 1020 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDT 124 +R T SD G Y C A+NS G R A++ + V + + S++ +QG Sbjct: 1021 SLEVRNT---TPSDGGRYQCMASNSNGVTR---ASVWLLVREAPQVSIHTRSQRFSQGME 1074 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 V + C G P P++ W + G+ L DSR+ + G L+IQ DAG Y C A N Sbjct: 1075 VRVRC-SASGYPAPHISWSREGRAL--QEDSRVRVDAQGTLIIQGVAPEDAGSYSCQAAN 1131 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 G R+ TL P + V+A G +C G P P V+W R G M Sbjct: 1132 EIG-RDEETVTLYYTDPPSVSAVNGVVLAAKGEEAVLECEATGVPPPRVIWYR--GDLEM 1188 Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304 L + G LR+ V D G Y+C A N +G SA L V P + P V V Sbjct: 1189 ILAPEDSI-SGMLRIPVVRERDAGVYTCRAVNELGDASAEIRLEVGHAPQLLELPQDVTV 1247 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTI-IFPGMSRDKYHATAVFDGVTVLTINDTDK 363 E G A C ATG P PT+ W ++ + + PG SR + + V +V+ Sbjct: 1248 ELGRSALLACRATGHPLPTITWHRGDDQPLGLRPG-SRTGWPDSGVLFFESVVP------ 1300 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423 + + VC A N G L VT PP I ++ P+ + L + +++ PC + Sbjct: 1301 -EDQALYVCEAENVFGKVQAEAYLLVTG--HVPPQIASSAPTVRVLERQPVSL-PCIVLA 1356 Query: 424 -TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482 P P W G L R ++ DG+L L D+G Y+CV S+ G + L Sbjct: 1357 GRPRPERRWLKAGMPLPPGSRHSIRADGSLHLDQALLEDAGRYSCVVSNTAGSHHRDVQL 1416 Query: 483 LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQV 540 +V P P I +++ P + P + T T++W++ +S Y V Sbjct: 1417 VVQVP--PRIQPTATHHITNEGVPASLPCVASGVPTP-TITWTKETNALASRDPHYNV 1471 Score = 157 bits (381), Expect = 2e-36 Identities = 130/479 (27%), Positives = 194/479 (40%), Gaps = 34/479 (7%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG--VLVVSDTHRSILPAGGL 66 G AP ++E P DVTV + A L CRA G P P I W++G L + R+ P G+ Sbjct: 1233 GHAPQLLELPQDVTVELGRSALLACRATGHPLPTITWHRGDDQPLGLRPGSRTGWPDSGV 1292 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126 F + V D +Y CEA N +G ++ L + + + + + V Sbjct: 1293 LFFESV---VPEDQALYVCEAENVFGKVQAEAYLLVTGHVPPQIASSAPTVRVLERQPVS 1349 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186 L C+ G P P W K G L SR + G+L + A DAGRY C+ N A Sbjct: 1350 LPCIVLAGRPRPERRWLKAGMPL--PPGSRHSIRADGSLHLDQALLEDAGRYSCVVSNTA 1407 Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 G+ + L + + P + + G + C G P P + W + Sbjct: 1408 GSHHRDV-QLVVQVPPRIQPTATHHITNEGVPASLPCVASGVPTPTITWTKETNALASRD 1466 Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS-------P 299 V DG+L + + D G Y C A N+VG S L+V P I ++ P Sbjct: 1467 PHYNVSKDGTLVIPRPSVQDAGAYVCTATNAVGFSSQEMRLSVNTKPRILVNGSHEADKP 1526 Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359 V ++G+ C A G P P + W+ + + D++H L + Sbjct: 1527 LRVTAKAGDEVTLDCEAQGSPPPLVTWTKDSRHMLPI----TDRHHLLPPGS----LHLA 1578 Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419 +DS C+A N AGS+ L V + PP + GP + + C Sbjct: 1579 QAQVSDS-GLYECTASNPAGSATQYYILRV-----QVPPQVQPGPRVLKVLVGEAVDLNC 1632 Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVW 478 A +PEP + W +G AL R +G++ + S +GTY C ASS G W Sbjct: 1633 VAEGSPEPRVTWSKDGVAL-----RGEGPEGSVHFAAIQTSHAGTYRCEASSSAGVDAW 1686 Score = 155 bits (377), Expect = 5e-36 Identities = 140/477 (29%), Positives = 191/477 (40%), Gaps = 33/477 (6%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80 V A+ + A L C A G P P + WY+G + ++ SI G+ + R DA Sbjct: 1157 VLAAKGEEAVLECEATGVPPPRVIWYRGDLEMILAPEDSI---SGMLRIPVVRER---DA 1210 Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140 GVY C A N G A S L V + L P+ G + +L C G P P + Sbjct: 1211 GVYTCRAVNELGDA-SAEIRLEVGHAPQLLEL-PQDVTVELGRSALLACRAT-GHPLPTI 1267 Query: 141 YWKK-NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG-TRESAIATLKI 198 W + + Q L SR D G L + D Y C A N G + A + Sbjct: 1268 TWHRGDDQPLGLRPGSRTGWPDSGVLFFESVVPEDQALYVCEAENVFGKVQAEAYLLVTG 1327 Query: 199 HIKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257 H+ P + + V V+ C V G P P+ W + AG P R + DGSL Sbjct: 1328 HVPPQIASSAPTVRVLERQPVSLPCIVLAGRPRPERRWLK-AGMPLPPGSRHSIRADGSL 1386 Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317 LD +L D G YSC N+ G+ L V PP I + G A C A+ Sbjct: 1387 HLDQALLEDAGRYSCVVSNTAGSHHRDVQLVVQVPPRIQPTATHHITNEGVPASLPCVAS 1446 Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377 G P PT+ W+ E N SRD H DG L I D+ VC+A N Sbjct: 1447 GVPTPTITWTKETNAL-----ASRDP-HYNVSKDG--TLVIPRPSVQDA-GAYVCTATNA 1497 Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA------VFPCTAICTPEPIIAW 431 G S +L+V + P I+ NG P++ A C A +P P++ W Sbjct: 1498 VGFSSQEMRLSVNT----KPRILVNGSHEADKPLRVTAKAGDEVTLDCEAQGSPPPLVTW 1553 Query: 432 YFEGEALIQ-NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 + ++ R ++ G+L L SDSG Y C AS+ G L V P Sbjct: 1554 TKDSRHMLPITDRHHLLPPGSLHLAQAQVSDSGLYECTASNPAGSATQYYILRVQVP 1610 Score = 153 bits (370), Expect = 4e-35 Identities = 147/534 (27%), Positives = 221/534 (41%), Gaps = 50/534 (9%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 +V V P C A G P+P I W+K G +V T G L G SD Sbjct: 2128 EVAVMEGHPVWFLCEARGVPTPDITWFKDGDPLVPSTEVVYTRGGRQLQLERAQG---SD 2184 Query: 80 AGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138 AG Y C+A+N+ G ++ ++V E P ++ G + LEC+ RG P P Sbjct: 2185 AGTYSCKASNAVGVVEKTTRLEVYVPPTIEGTGEGPRVVKAVAGRPLTLECV-ARGYPPP 2243 Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI-ATLK 197 V W G ++ D + GG L ++ + G Y C+A + AG E+ + +++ Sbjct: 2244 TVSWYHEGLPVV-DRNGTWLGAGGGVLSLESLGEASGGLYSCVASSPAG--EAVLHYSVE 2300 Query: 198 IHIKPYLIT--GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255 + + P L+ G V G S+ C G P+P + W ++ G L V V +G Sbjct: 2301 VQVAPQLLVAEGLGQVTTLVGQSLYLPCYASGSPVPTIQWLQN-GHPAEELPGVHVTSEG 2359 Query: 256 -SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL-SPNSVNVESGNVARFT 313 +L +D+V L G ++C+A N G +A L+V++ PS+ + ++ Sbjct: 2360 TTLHIDHVELGHAGLFACQATNEAGTAAAEVELSVHELPSVVIVGGENITAPFLQPVTLR 2419 Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373 C TG P P++ W +G A A G L I D D T C Sbjct: 2420 CAGTGVPTPSLRWWKDG--------------VALAASGG--SLQIEKVDLKD-EGTYTCV 2462 Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF 433 A N AG S L V PP I G N+ + + C A P P I+W+ Sbjct: 2463 ATNLAGESRKEVILRVL-----VPPNIEPGLVNKAVLENASVTLECLASGVPPPDISWFK 2517 Query: 434 EGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492 + + R V+ DG L+++ SD+G+Y CVAS+ G +L V+ P P I Sbjct: 2518 GRQPISAWDRAMVSTDGRVLLIEQAQLSDAGSYRCVASNVVGSTELQYSLRVNVP--PRI 2575 Query: 493 HFFRAADVSSLPGP-----PTKPITHNVTDTSVTLSW-SQNNKIGSSSILGYQV 540 SLPGP P + S L W N + ++ G QV Sbjct: 2576 TL-----PPSLPGPVLLHSPVRLTCDAAGAPSPMLMWLKDGNPVSTAGTAGLQV 2624 Score = 134 bits (324), Expect = 1e-29 Identities = 140/470 (29%), Positives = 204/470 (43%), Gaps = 43/470 (9%) Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75 E P V +P TL C A G P P + WY G+ VV D + + L AGG + G Sbjct: 2218 EGPRVVKAVAGRPLTLECVARGYPPPTVSWYHEGLPVV-DRNGTWLGAGGGVLSLESLGE 2276 Query: 76 VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDTVVLECLPPRG 134 + G+Y C A++ G A + ++ V V + E + + G ++ L C G Sbjct: 2277 --ASGGLYSCVASSPAGEA-VLHYSVEVQVAPQLLVAEGLGQVTTLVGQSLYLPCYAS-G 2332 Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193 SP P + W +NG + +H+ +G L I AG + C A N AGT +A Sbjct: 2333 SPVPTIQWLQNGHPA--EELPGVHVTSEGTTLHIDHVELGHAGLFACQATNEAGT-AAAE 2389 Query: 194 ATLKIHIKP-YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL 252 L +H P +I G E++ A VT +C G P P + W + G Sbjct: 2390 VELSVHELPSVVIVGGENITAPFLQPVTLRCAGTGVPTPSLRWWKD--------GVALAA 2441 Query: 253 DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN---VESGNV 309 GSL+++ V L DEG Y+C A N G L V PP N+ P VN +E+ +V Sbjct: 2442 SGGSLQIEKVDLKDEGTYTCVATNLAGESRKEVILRVLVPP--NIEPGLVNKAVLENASV 2499 Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369 C A+G P P + W +G + P + D+ A DG VL I +D+ + Sbjct: 2500 T-LECLASGVPPPDISW-FKGRQ----PISAWDR--AMVSTDG-RVLLIEQAQLSDA-GS 2549 Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPS-NQTLPIKSMAVFPCTAICTPEPI 428 C A N GS+ ++ L V PP IT PS + + S C A P P+ Sbjct: 2550 YRCVASNVVGSTELQYSLRV-----NVPPRITLPPSLPGPVLLHSPVRLTCDAAGAPSPM 2604 Query: 429 IAWYFEGEALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 + W +G + + L+L SDSG+Y+CVA S G+ Sbjct: 2605 LMWLKDGNPVSTAGTAGLQVFPGGRVLMLASARVSDSGSYSCVAVSAVGE 2654 Score = 132 bits (318), Expect = 7e-29 Identities = 104/335 (31%), Positives = 139/335 (41%), Gaps = 21/335 (6%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRA-GGSPSPAIRWYKGGVLVVSDTHRSILPAG 64 VT P I V V QP +L C G P P RW K G+ + + SI G Sbjct: 1325 VTGHVPPQIASSAPTVRVLERQPVSLPCIVLAGRPRPERRWLKAGMPLPPGSRHSIRADG 1384 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ--SAQG 122 L +A + DAG Y C +N+ G+ R+ L V V R++P + + +G Sbjct: 1385 SLHLDQA----LLEDAGRYSCVVSNTAGS-HHRDVQLVVQVPP---RIQPTATHHITNEG 1436 Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182 L C+ G P P + W K L D ++ G LVI DAG Y C A Sbjct: 1437 VPASLPCVAS-GVPTPTITWTKETNALA-SRDPHYNVSKDGTLVIPRPSVQDAGAYVCTA 1494 Query: 183 RNAAGTRESAIATLKIHIKP-YLITG------PEDVVAQTGSSVTFQCRVGGDPLPDVLW 235 NA G + L ++ KP L+ G P V A+ G VT C G P P V W Sbjct: 1495 TNAVGFSSQEMR-LSVNTKPRILVNGSHEADKPLRVTAKAGDEVTLDCEAQGSPPPLVTW 1553 Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295 + + R +L GSL L ++D G Y C A N G+ + L V PP + Sbjct: 1554 TKDSRHMLPITDRHHLLPPGSLHLAQAQVSDSGLYECTASNPAGSATQYYILRVQVPPQV 1613 Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330 P + V G C A G PEP + WS +G Sbjct: 1614 QPGPRVLKVLVGEAVDLNCVAEGSPEPRVTWSKDG 1648 Score = 130 bits (314), Expect = 2e-28 Identities = 123/435 (28%), Positives = 172/435 (39%), Gaps = 43/435 (9%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80 VT Q L C A GSP P I+W + G + G L H + A Sbjct: 2316 VTTLVGQSLYLPCYASGSPVPTIQWLQNGHPAEELPGVHVTSEGTT--LHIDHVEL-GHA 2372 Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140 G++ C+ATN GTA + L V L + E+ + V L C G P P++ Sbjct: 2373 GLFACQATNEAGTAAAE-VELSVHELPSVVIVGGENITAPFLQPVTLRCAGT-GVPTPSL 2430 Query: 141 YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200 W K+G L GG+L I+ D G Y C+A N AG + L++ + Sbjct: 2431 RWWKDGVALA---------ASGGSLQIEKVDLKDEGTYTCVATNLAGESRKEVI-LRVLV 2480 Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---RVKVLDDGS- 256 P + G + +SVT +C G P PD+ W + G P+ R V DG Sbjct: 2481 PPNIEPGLVNKAVLENASVTLECLASGVPPPDISWFK----GRQPISAWDRAMVSTDGRV 2536 Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN-VESGNVARFTCT 315 L ++ L+D G Y C A N VG+ L V PP I L P+ V + R TC Sbjct: 2537 LLIEQAQLSDAGSYRCVASNVVGSTELQYSLRVNVPPRITLPPSLPGPVLLHSPVRLTCD 2596 Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375 A G P P + W +GN +S VF G VL + +DS + C AV Sbjct: 2597 AAGAPSPMLMWLKDGNP------VSTAGTAGLQVFPGGRVLMLASARVSDS-GSYSCVAV 2649 Query: 376 NYAGSSFVRGKLTVTSDDDRP------------PPIITNGPSNQTLPIKSMAVFPCTAIC 423 + G L V S+ P PP I N ++ C + Sbjct: 2650 SAVGEDRRDVVLRVHSESRAPEAAGCGLEAQDAPPSILGEEQNVSVVANESVALECRSHA 2709 Query: 424 TPEPIIAWYFEGEAL 438 P P+++W +G L Sbjct: 2710 VPPPVLSWRKDGRPL 2724 Score = 122 bits (293), Expect = 8e-26 Identities = 107/419 (25%), Positives = 166/419 (39%), Gaps = 28/419 (6%) Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS-AQGDTVVLECLPPRGSP 136 ++ G Y C A + GT R++ + V +L P + + G+T +L CL +P Sbjct: 939 AEEGTYECTAVSRAGTGRAKT---QIVVTGPPPQLVPVPNVTVSPGETAILSCLVLSEAP 995 Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196 N+ W ++ + L L D +L +++ +D GRYQC+A N+ G +++ L Sbjct: 996 Y-NLTWVRDWRVLSASTGRVTQLAD-LSLEVRNTTPSDGGRYQCMASNSNGVTRASV-WL 1052 Query: 197 KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS 256 + P + G V +C G P P + W R G RV+V G+ Sbjct: 1053 LVREAPQVSIHTRSQRFSQGMEVRVRCSASGYPAPHISWSRE-GRALQEDSRVRVDAQGT 1111 Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316 L + V D G YSC+A N +G + L DPPS++ V G A C A Sbjct: 1112 LIIQGVAPEDAGSYSCQAANEIGRDEETVTLYYTDPPSVSAVNGVVLAAKGEEAVLECEA 1171 Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376 TG P P + W G+ +I A D ++ + + C AVN Sbjct: 1172 TGVPPPRVIW-YRGDLEMIL-----------APEDSISGMLRIPVVRERDAGVYTCRAVN 1219 Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436 G + +L V P + P + T+ + A+ C A P P I W+ + Sbjct: 1220 ELGDASAEIRLEVGH-----APQLLELPQDVTVELGRSALLACRATGHPLPTITWHRGDD 1274 Query: 437 ---ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492 L R + G L + + D Y C A + GK LLV + P I Sbjct: 1275 QPLGLRPGSRTGWPDSGVLFFESVVPEDQALYVCEAENVFGKVQAEAYLLVTGHVPPQI 1333 Score = 109 bits (263), Expect = 3e-22 Identities = 92/284 (32%), Positives = 132/284 (46%), Gaps = 21/284 (7%) Query: 37 GSPSPAIRWYKG--GVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTA 94 G+P P + W KG + ++L G LF + SD G Y C+ATN G+A Sbjct: 1813 GTPKPQVTWRKGPSSEPLRDRPGLAVLDEGSLFLASVSP----SDGGDYECQATNEAGSA 1868 Query: 95 RSRNATLHVAV---LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLF 151 SR A L V V LRE+ R S + G ++ LEC G P P + W KNG+ + Sbjct: 1869 -SRRAKLVVHVPPSLREDGRRANVSGMA--GQSLTLEC-DANGFPAPEITWLKNGRQIPA 1924 Query: 152 DGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI--TGP 208 G R L+DG L ++ D+G Y C A N AGT + L + I P ++ Sbjct: 1925 VGSHR--LLDGARALHFPRIQEGDSGLYSCRAENQAGTAQRDFDLLVL-IPPSVLGAEAA 1981 Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADE 267 ++VV G+ +CR G P P V W + + RV++ +DG LR+ N L DE Sbjct: 1982 QEVVGLAGAGAELECRTLGVPTPQVEWTKDGQPVFLGEPRVQLQEDGQVLRITNSHLGDE 2041 Query: 268 GEYSCEAENSVGAVSASGYLTVYDPPS-INLSPNSVNVESGNVA 310 G Y C A + G + L ++ PS SP + + G +A Sbjct: 2042 GWYQCVAFSPAGQQTKDFQLRIHGEPSPFPSSPRAAHCVEGWLA 2085 Score = 99 bits (238), Expect = 4e-19 Identities = 86/309 (27%), Positives = 127/309 (41%), Gaps = 20/309 (6%) Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVG 226 I A + + G Y+C A + AGT + + P L+ P +V G + C V Sbjct: 933 IPRASKAEEGTYECTAVSRAGTGRAKTQIVVTGPPPQLVPVP-NVTVSPGETAILSCLVL 991 Query: 227 GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY 286 + ++ W R + GRV L D SL + N +D G Y C A NS G AS + Sbjct: 992 SEAPYNLTWVRDWRVLSASTGRVTQLADLSLEVRNTTPSDGGRYQCMASNSNGVTRASVW 1051 Query: 287 LTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHA 346 L V + P +++ S G R C+A+G P P + WS EG R + R Sbjct: 1052 LLVREAPQVSIHTRSQRFSQGMEVRVRCSASGYPAPHISWSREG-RALQEDSRVRVDAQG 1110 Query: 347 TAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN 406 T + GV + + C A N G R + TVT PP + + + Sbjct: 1111 TLIIQGVA---------PEDAGSYSCQAANEIG----RDEETVTLYYTDPPSV--SAVNG 1155 Query: 407 QTLPIK-SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465 L K AV C A P P + WY +I +++ G L + + + D+G Y Sbjct: 1156 VVLAAKGEEAVLECEATGVPPPRVIWYRGDLEMILAPEDSIS--GMLRIPVVRERDAGVY 1213 Query: 466 TCVASSRHG 474 TC A + G Sbjct: 1214 TCRAVNELG 1222 Score = 94.3 bits (224), Expect = 2e-17 Identities = 61/203 (30%), Positives = 95/203 (46%), Gaps = 9/203 (4%) Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193 G+P+P V W+K + + ++D G+L + +D G Y+C A N AG+ S Sbjct: 1813 GTPKPQVTWRKGPSSEPLRDRPGLAVLDEGSLFLASVSPSDGGDYECQATNEAGS-ASRR 1871 Query: 194 ATLKIHIKPYLITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP-LGRVK 250 A L +H+ P L +V G S+T +C G P P++ W ++ G +P +G + Sbjct: 1872 AKLVVHVPPSLREDGRRANVSGMAGQSLTLECDANGFPAPEITWLKN--GRQIPAVGSHR 1929 Query: 251 VLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE--SG 307 +LD +L + D G YSC AEN G L V PPS+ + + V +G Sbjct: 1930 LLDGARALHFPRIQEGDSGLYSCRAENQAGTAQRDFDLLVLIPPSVLGAEAAQEVVGLAG 1989 Query: 308 NVARFTCTATGRPEPTMFWSVEG 330 A C G P P + W+ +G Sbjct: 1990 AGAELECRTLGVPTPQVEWTKDG 2012 Score = 85.8 bits (203), Expect = 6e-15 Identities = 75/257 (29%), Positives = 109/257 (42%), Gaps = 23/257 (8%) Query: 227 GDPLPDVLWRRSAGGGNMPLGR---VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSA 283 G P P V WR+ G + PL + VLD+GSL L +V +D G+Y C+A N G+ S Sbjct: 1813 GTPKPQVTWRK--GPSSEPLRDRPGLAVLDEGSLFLASVSPSDGGDYECQATNEAGSASR 1870 Query: 284 SGYLTVYDPPSINLSPNSVNVE--SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341 L V+ PPS+ NV +G C A G P P + W ++ R I G R Sbjct: 1871 RAKLVVHVPPSLREDGRRANVSGMAGQSLTLECDANGFPAPEITW-LKNGRQIPAVGSHR 1929 Query: 342 DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401 + DG L + DS C A N AG++ L V PP ++ Sbjct: 1930 -------LLDGARALHFPRIQEGDS-GLYSCRAENQAGTAQRDFDLLVLI----PPSVLG 1977 Query: 402 NGPSNQTLPIKSM-AVFPCTAICTPEPIIAWYFEGEALIQNHRR-NVTNDG-TLVLKDLD 458 + + + + A C + P P + W +G+ + R + DG L + + Sbjct: 1978 AEAAQEVVGLAGAGAELECRTLGVPTPQVEWTKDGQPVFLGEPRVQLQEDGQVLRITNSH 2037 Query: 459 KSDSGTYTCVASSRHGK 475 D G Y CVA S G+ Sbjct: 2038 LGDEGWYQCVAFSPAGQ 2054 Score = 80.6 bits (190), Expect = 2e-13 Identities = 62/179 (34%), Positives = 89/179 (49%), Gaps = 11/179 (6%) Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVS-DTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85 Q TL C A G P+P I W K G + + +HR + A L F R G D+G+Y C Sbjct: 1897 QSLTLECDANGFPAPEITWLKNGRQIPAVGSHRLLDGARALHFPRIQEG----DSGLYSC 1952 Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPESKQ-SAQGDTVVLECLPPRGSPEPNVYWKK 144 A N GTA+ R+ L V + E + G LEC G P P V W K Sbjct: 1953 RAENQAGTAQ-RDFDLLVLIPPSVLGAEAAQEVVGLAGAGAELECRT-LGVPTPQVEWTK 2010 Query: 145 NGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKP 202 +GQ +F G+ R+ L + G ++ I ++ D G YQC+A + AG +++ L+IH +P Sbjct: 2011 DGQP-VFLGEPRVQLQEDGQVLRITNSHLGDEGWYQCVAFSPAG-QQTKDFQLRIHGEP 2067 Score = 51.6 bits (118), Expect = 1e-04 Identities = 53/193 (27%), Positives = 82/193 (42%), Gaps = 22/193 (11%) Query: 292 PPSI--NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349 PP+I + + V V G+ F C A G P P + W +G+ + S + + Sbjct: 2117 PPTIWGSNETSEVAVMEGHPVWFLCEARGVPTPDITWFKDGDPLV----PSTEVVYTR-- 2170 Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409 G L + +D+ T C A N G +L V PP I G + Sbjct: 2171 --GGRQLQLERAQGSDA-GTYSCKASNAVGVVEKTTRLEVYV----PPTIEGTGEGPRV- 2222 Query: 410 PIKSMAVFPCTAICT----PEPIIAWYFEGEALIQNHRRNV-TNDGTLVLKDLDKSDSGT 464 +K++A P T C P P ++WY EG ++ + + G L L+ L ++ G Sbjct: 2223 -VKAVAGRPLTLECVARGYPPPTVSWYHEGLPVVDRNGTWLGAGGGVLSLESLGEASGGL 2281 Query: 465 YTCVASSRHGKYV 477 Y+CVASS G+ V Sbjct: 2282 YSCVASSPAGEAV 2294 >UniRef50_UPI0000F1ECB4 Cluster: PREDICTED: similar to hemicentin 1,; n=1; Danio rerio|Rep: PREDICTED: similar to hemicentin 1, - Danio rerio Length = 413 Score = 160 bits (388), Expect = 2e-37 Identities = 126/429 (29%), Positives = 189/429 (44%), Gaps = 31/429 (7%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 EAP ++ P + + ++C A GSP P + W G + +S+ HR + G+ + Sbjct: 4 EAPSVVVSPQTQSFSLGAEVHISCSASGSPPPKVFWSHGNIF-LSNHHRMSISESGMLTI 62 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 R G D+G Y C ATN GTA S++ ++ A + + G+ LEC Sbjct: 63 R---GAAPEDSGNYTCLATNEVGTA-SQSVNVNYAE-PPSISVVQQMVMVVAGEDASLEC 117 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189 G+P P V W+K G L V G L I+ ++ D+G Y C+A N AG+ Sbjct: 118 -QASGTPSPIVKWQK-GDLDLGTAPFAEQDVHRGTLQIRGVQELDSGDYTCVASNIAGS- 174 Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG----GGNMP 245 SA+ L++ P P D+ A G ++T C G P P ++WRR G G + Sbjct: 175 SSAVVVLQVGAAPTFSESPVDITASVGDNITLPCIARGFPTPSLIWRRQDGRPIFGKSSG 234 Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV--YDPPSINLSPNSVN 303 L G+L++ +V + DEG Y CEA+N G++ A +TV +PP + S+ Sbjct: 235 HVGTSQLPSGALQIQSVWVDDEGVYLCEAKNQFGSIKALARVTVTGLEPPLLVQGAPSIT 294 Query: 304 VESGNVARFTC-TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362 C G P P W+ G + R DG L ++ Sbjct: 295 TMIAQPLNLPCRLLDGIPLPERIWTHNGKQV-------RVGGRVFLRSDG--SLHVDRAV 345 Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422 D+ T VC+AVN AGS+ +TVT + PP I GP + T + C A Sbjct: 346 PEDA-GTYVCTAVNVAGSA----NITVTVEVHAPPD-IKAGPLHYTASEGTPISLSCEAR 399 Query: 423 CTPEPIIAW 431 P+P I+W Sbjct: 400 GVPKPTISW 408 Score = 134 bits (323), Expect = 2e-29 Identities = 100/334 (29%), Positives = 147/334 (44%), Gaps = 26/334 (7%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV------LVVSDTHRS 59 V E P I V V + A+L C+A G+PSP ++W KG + D HR Sbjct: 90 VNYAEPPSISVVQQMVMVVAGEDASLECQASGTPSPIVKWQKGDLDLGTAPFAEQDVHRG 149 Query: 60 ILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS 119 L G+ L D+G Y C A+N G++ S L V F P + Sbjct: 150 TLQIRGVQEL---------DSGDYTCVASNIAGSS-SAVVVLQVGAA-PTFSESPVDITA 198 Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL----VDGGNLVIQDARQTDA 175 + GD + L C+ RG P P++ W++ +F G S H+ + G L IQ D Sbjct: 199 SVGDNITLPCIA-RGFPTPSLIWRRQDGRPIF-GKSSGHVGTSQLPSGALQIQSVWVDDE 256 Query: 176 GRYQCIARNAAGTRES-AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDV 233 G Y C A+N G+ ++ A T+ P L+ G + + CR+ G PLP+ Sbjct: 257 GVYLCEAKNQFGSIKALARVTVTGLEPPLLVQGAPSITTMIAQPLNLPCRLLDGIPLPER 316 Query: 234 LWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293 +W + + GRV + DGSL +D + D G Y C A N G+ + + + V+ PP Sbjct: 317 IWTHNGKQVRVG-GRVFLRSDGSLHVDRAVPEDAGTYVCTAVNVAGSANITVTVEVHAPP 375 Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327 I P G +C A G P+PT+ WS Sbjct: 376 DIKAGPLHYTASEGTPISLSCEARGVPKPTISWS 409 Score = 131 bits (317), Expect = 1e-28 Identities = 97/360 (26%), Positives = 152/360 (42%), Gaps = 15/360 (4%) Query: 112 LEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR 171 + P+++ + G V + C GSP P V+W + RM + + G L I+ A Sbjct: 10 VSPQTQSFSLGAEVHISC-SASGSPPPKVFWSHGN--IFLSNHHRMSISESGMLTIRGAA 66 Query: 172 QTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231 D+G Y C+A N GT ++ + P + + V+ G + +C+ G P P Sbjct: 67 PEDSGNYTCLATNEVGTASQSV-NVNYAEPPSISVVQQMVMVVAGEDASLECQASGTPSP 125 Query: 232 DVLWRRS-AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290 V W++ G P V G+L++ V D G+Y+C A N G+ SA L V Sbjct: 126 IVKWQKGDLDLGTAPFAEQDV-HRGTLQIRGVQELDSGDYTCVASNIAGSSSAVVVLQVG 184 Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350 P+ + SP + G+ C A G P P++ W + R I G S + + Sbjct: 185 AAPTFSESPVDITASVGDNITLPCIARGFPTPSLIWRRQDGRPIF--GKSSGHVGTSQLP 242 Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410 G L I +D +C A N GS ++TVT + PP++ G + T Sbjct: 243 SGA--LQIQSVWVDDE-GVYLCEAKNQFGSIKALARVTVTGLE---PPLLVQGAPSITTM 296 Query: 411 IKSMAVFPCTAIC-TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469 I PC + P P W G+ + R + +DG+L + D+GTY C A Sbjct: 297 IAQPLNLPCRLLDGIPLPERIWTHNGKQVRVGGRVFLRSDGSLHVDRAVPEDAGTYVCTA 356 Score = 93.9 bits (223), Expect = 2e-17 Identities = 70/235 (29%), Positives = 104/235 (44%), Gaps = 14/235 (5%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG---VLVVSDTH--RSILPA 63 G AP E P+D+T + TL C A G P+P++ W + + S H S LP+ Sbjct: 184 GAAPTFSESPVDITASVGDNITLPCIARGFPTPSLIWRRQDGRPIFGKSSGHVGTSQLPS 243 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQG 122 G L D GVY CEA N +G+ ++ A + V L ++ S + Sbjct: 244 GALQIQSVWV----DDEGVYLCEAKNQFGSIKAL-ARVTVTGLEPPLLVQGAPSITTMIA 298 Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182 + L C G P P W NG+ + G R+ L G+L + A DAG Y C A Sbjct: 299 QPLNLPCRLLDGIPLPERIWTHNGKQVRVGG--RVFLRSDGSLHVDRAVPEDAGTYVCTA 356 Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 N AG+ + T+++H P + GP A G+ ++ C G P P + W + Sbjct: 357 VNVAGSANITV-TVEVHAPPDIKAGPLHYTASEGTPISLSCEARGVPKPTISWSK 410 Score = 89.8 bits (213), Expect = 4e-16 Identities = 75/281 (26%), Positives = 107/281 (38%), Gaps = 26/281 (9%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---RVKVLDDGSLR 258 P ++ P+ G+ V C G P P V W GN+ L R+ + + G L Sbjct: 6 PSVVVSPQTQSFSLGAEVHISCSASGSPPPKVFWSH----GNIFLSNHHRMSISESGMLT 61 Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATG 318 + D G Y+C A N VG S S + +PPSI++ V V +G A C A+G Sbjct: 62 IRGAAPEDSGNYTCLATNEVGTASQSVNVNYAEPPSISVVQQMVMVVAGEDASLECQASG 121 Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378 P P + W P +D + T GV L D C A N A Sbjct: 122 TPSPIVKWQKGDLDLGTAPFAEQDVHRGTLQIRGVQELDSGD---------YTCVASNIA 172 Query: 379 GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-YFEGEA 437 GSS L V + P + P + T + PC A P P + W +G Sbjct: 173 GSSSAVVVLQVGA-----APTFSESPVDITASVGDNITLPCIARGFPTPSLIWRRQDGRP 227 Query: 438 LIQNHRRNVTN----DGTLVLKDLDKSDSGTYTCVASSRHG 474 + +V G L ++ + D G Y C A ++ G Sbjct: 228 IFGKSSGHVGTSQLPSGALQIQSVWVDDEGVYLCEAKNQFG 268 Score = 61.7 bits (143), Expect = 1e-07 Identities = 53/186 (28%), Positives = 82/186 (44%), Gaps = 18/186 (9%) Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350 + PS+ +SP + + G +C+A+G P P +FWS GN IF +H ++ Sbjct: 4 EAPSVVVSPQTQSFSLGAEVHISCSASGSPPPKVFWS-HGN---IF----LSNHHRMSIS 55 Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410 + +LTI DS N C A N G++ + PP I+ + Sbjct: 56 ES-GMLTIRGAAPEDSGN-YTCLATNEVGTASQSVNVNYAE-----PPSISVVQQMVMVV 108 Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQN--HRRNVTNDGTLVLKDLDKSDSGTYTCV 468 A C A TP PI+ W +G+ + + GTL ++ + + DSG YTCV Sbjct: 109 AGEDASLECQASGTPSPIVKWQ-KGDLDLGTAPFAEQDVHRGTLQIRGVQELDSGDYTCV 167 Query: 469 ASSRHG 474 AS+ G Sbjct: 168 ASNIAG 173 >UniRef50_Q9VS29 Cluster: CG32387-PA, isoform A; n=15; Endopterygota|Rep: CG32387-PA, isoform A - Drosophila melanogaster (Fruit fly) Length = 1770 Score = 160 bits (388), Expect = 2e-37 Identities = 200/847 (23%), Positives = 346/847 (40%), Gaps = 89/847 (10%) Query: 9 GEAPYIIEQPLDVTVARHQPA-TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI---LPAG 64 G+AP ++ + PA +L C A G+P+P I W G + S+ I + Sbjct: 385 GDAPPVLLYSFIEQTLQPGPAVSLKCSAAGNPTPQISWTLDGFPLPSNGRFMIGQYITVH 444 Query: 65 G--LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122 G + + +H V D G Y C A N G + A L++ L RL P+ + G Sbjct: 445 GDVISHVNISHVMVE-DGGEYACIAENRAGRVQHA-ARLNIYGL-PYIRLIPKVT-AVSG 500 Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ-TDAGRYQCI 181 +T+ L+C P G P ++W++ G+ L D R + G+L I ++ +D+G Y C Sbjct: 501 ETLNLKC-PVAGYPIEEIHWERGGREL--PDDIRQRVQPDGSLTISPVQKNSDSGVYTCW 557 Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAG 240 ARN G + + + P + G C V GDP ++W + Sbjct: 558 ARNKQGHSARRSGEVTVIVPPSIEPFAFQEGLAEGMRTRTVCGVSRGDPPLKLIWLKD-- 615 Query: 241 GGNMP--LG-RVKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295 G +P LG V +LD S L + ++ GEY+C A+N + + L V PP Sbjct: 616 GDPLPDLLGANVTMLDQYSSLLSIPSLSATHSGEYTCVAKNPAAEIKYTALLQVKVPPRW 675 Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFW-SVEGNRTIIFPGMSRDKYHATAVFDGVT 354 + P NVE C A G P P++ W G+++ + + R++ + +G Sbjct: 676 IVEPVDANVERNRHIMLHCQAQGVPTPSIVWKKATGSKSGEYEEV-RERPFTKLLGNGSL 734 Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414 +L K D +C A N G+ GK+ + P + S + K Sbjct: 735 LL---QHVKEDREGFYLCQANNGIGTGI--GKVIQLKVNSSP---YFSSTSRSVMVKKGD 786 Query: 415 AVFPCTAICTPEPI-IAWYFEGEALIQ---NHRRNVTNDGT-------LVLKDLDKSDSG 463 A+ +PI I W G+ + N++ +V + T L ++ +D +DSG Sbjct: 787 TALLQCAVSGDKPINIVWMRSGKNTLNPSTNYKISVKQEATPDGVSAELQIRTVDATDSG 846 Query: 464 TYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLS 523 Y C AS+ +G L V P P PP+ ++ SV + Sbjct: 847 PYFCRASNLYGNDQQLVQLQVQEP----------------PLPPSVLEAAMISSRSVNIK 890 Query: 524 WSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITY 583 W Q +G+ + Y VE + L + + + + + ++++L P Y Sbjct: 891 W-QPKTLGTGDVTKYIVEFREADPLFVDQWQQ------IEVKDPPHFNAMIENLKPATRY 943 Query: 584 MFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATP 643 F V E S G S P S + V + G S R T+ ++ + P Sbjct: 944 AFRVIAEGSAGRSAP---SQELIVRTEPQ---RPAGPPLSLSARPLSSTELLISWVAPLP 997 Query: 644 IDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFE--ITSLRKYT 701 L ++G + ++ + Y ++ D E ++ L K+ Sbjct: 998 -----------ELRHGDIQGYNVGYKLSSSGNTAYNFTSVSGDGDGGNGELLLSGLAKFA 1046 Query: 702 KYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQN 761 +Y + F + G S AQT++DVP PP ++ L++ ++ + W PP + N Sbjct: 1047 RYTVVVQAFNQVGPGPLSEPTAAQTMEDVPSRPPEDVRCAALSSQSLQVSWQPPPIYHTN 1106 Query: 762 GIITGYNVVVNWL--DVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819 G++ GY ++ + D+ +K V T A ++++T L +YS+Q+ A T +G G Sbjct: 1107 GLLQGYKLIFEPIIDDIQPSKDEVESRKTT--ALTMVLTGLRKYTNYSIQVLAHTRMGDG 1164 Query: 820 PFSQKVY 826 S+ ++ Sbjct: 1165 VVSKPLF 1171 Score = 137 bits (331), Expect = 2e-30 Identities = 126/490 (25%), Positives = 206/490 (42%), Gaps = 45/490 (9%) Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTH--RSILPAGGLFFLRAT 72 +E P V + L+C A GSP P + W V++ H R +L G L + Sbjct: 1 MEPPGRVEFSNSSGGWLDCSASGSPQPTVDWVHADGSAVTEIHGVRRVLRNGTLVLMPFA 60 Query: 73 HGRVHSDAG--VYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130 H D +Y C A+NS G SR+ + AV+ + ++++ E +A+G T +L C+ Sbjct: 61 AAAYHQDVHNTIYRCIASNSVGRIVSRDVQVR-AVVAQAYKVDVEVLSAARGCTAILRCV 119 Query: 131 PPRGSPE--PNVYWKKNGQTLLF---DGDSRMHLVDGGNLVIQDARQTDAGR-YQCIARN 184 P E V W ++ GD + HL+ G L+I + +++D + ++C + + Sbjct: 120 VPTFVKELVRVVSWVHEPAIYIYPSLQGDGKFHLLPTGELLIHNLQESDESQSFRCRSMH 179 Query: 185 AAGTRESAIAT---LKIH-----IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 TR+ +++ L+I+ I P ++ V C G P P+ W Sbjct: 180 RL-TRQVVVSSPTRLRINSHRGIISPSVVEHTAHVQVSQDEGAVLLCVAQGCPSPEYSWF 238 Query: 237 RSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293 G G +P+ RV++L L ++ V D G Y C A N G SA LTV P Sbjct: 239 THNGAGPLPVLSGPRVRLLGP-ILAIEAVTGEDSGVYKCTAGNVGGEASAELRLTVATPI 297 Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353 + +SPN ++V G A F C T P G + I++ R + V D + Sbjct: 298 QVEISPNVLSVHMGGTAEFRCLVTSNGSPV------GMQNILWYKDGRQLPSSGRVEDTL 351 Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413 V ++ ++R C G +F + T PP++ QTL Sbjct: 352 VVPRVS----RENRGMYQCVVRRPEGDTF---QATAELQLGDAPPVLLYSFIEQTLQPGP 404 Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHR----RNVTNDGTLV----LKDLDKSDSGTY 465 C+A P P I+W +G L N R + +T G ++ + + D G Y Sbjct: 405 AVSLKCSAAGNPTPQISWTLDGFPLPSNGRFMIGQYITVHGDVISHVNISHVMVEDGGEY 464 Query: 466 TCVASSRHGK 475 C+A +R G+ Sbjct: 465 ACIAENRAGR 474 Score = 133 bits (322), Expect = 2e-29 Identities = 142/497 (28%), Positives = 199/497 (40%), Gaps = 47/497 (9%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK---GGVLVVSDTHRSILPAGGLF 67 +P ++E V V++ + A L C A G PSP W+ G L V R L G + Sbjct: 203 SPSVVEHTAHVQVSQDEGAVLLCVAQGCPSPEYSWFTHNGAGPLPVLSGPRVRL-LGPIL 261 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127 + A G D+GVY C A N G A S L VA + + P G T Sbjct: 262 AIEAVTG---EDSGVYKCTAGNVGGEA-SAELRLTVAT-PIQVEISPNVLSVHMGGTAEF 316 Query: 128 ECL-PPRGSP--EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 CL GSP N+ W K+G+ L G R+ LV+ + + G YQC+ R Sbjct: 317 RCLVTSNGSPVGMQNILWYKDGRQLPSSG--RVE----DTLVVPRVSRENRGMYQCVVRR 370 Query: 185 AAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA---- 239 G A A L++ P L+ + Q G +V+ +C G+P P + W Sbjct: 371 PEGDTFQATAELQLGDAPPVLLYSFIEQTLQPGPAVSLKCSAAGNPTPQISWTLDGFPLP 430 Query: 240 GGGNMPLGR-VKVLDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296 G +G+ + V D + + +V++ D GEY+C AEN G V + L +Y P I Sbjct: 431 SNGRFMIGQYITVHGDVISHVNISHVMVEDGGEYACIAENRAGRVQHAARLNIYGLPYIR 490 Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356 L P V SG C G P + W G R + P R + DG L Sbjct: 491 LIP-KVTAVSGETLNLKCPVAGYPIEEIHWE-RGGREL--PDDIRQRVQP----DG--SL 540 Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVR-GKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415 TI+ KN C A N G S R G++TV PP I + L Sbjct: 541 TISPVQKNSDSGVYTCWARNKQGHSARRSGEVTVI-----VPPSIEPFAFQEGLAEGMRT 595 Query: 416 VFPCTAICTPEPI-IAWYFEGEALIQNHRRNVT----NDGTLVLKDLDKSDSGTYTCVAS 470 C P+ + W +G+ L NVT L + L + SG YTCVA Sbjct: 596 RTVCGVSRGDPPLKLIWLKDGDPLPDLLGANVTMLDQYSSLLSIPSLSATHSGEYTCVAK 655 Query: 471 SRHGKYVWSGALLVDSP 487 + + ++ L V P Sbjct: 656 NPAAEIKYTALLQVKVP 672 Score = 48.4 bits (110), Expect = 0.001 Identities = 45/211 (21%), Positives = 90/211 (42%), Gaps = 15/211 (7%) Query: 637 ELIEATPIDSKTIKLMWEILNFYYLEGLF----IYFRPLDNITIEYEMKTILHSNDVSGF 692 E + + S+++++ W+ Y+ GL + F P+ + + + Sbjct: 1081 EDVRCAALSSQSLQVSWQPPPIYHTNGLLQGYKLIFEPIIDDIQPSKDEVESRKTTALTM 1140 Query: 693 EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKW 752 +T LRKYT Y ++ + +G S + +DVP+ P +I++ ++ ++++ W Sbjct: 1141 VLTGLRKYTNYSIQVLAHTRMGDGVVSKPLFCHSEEDVPEA-PADIKVVSSSSQSLYISW 1199 Query: 753 SPPELQLQNGIITGYNV---VVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQ 809 PP NG+IT Y++ VVN + N+ + Q L + Y Sbjct: 1200 LPP--NEPNGVITKYSLYTRVVNGREELNNEK----RSLPSQQAYYEAKGLHPHMEYQFW 1253 Query: 810 IAAETIIGLGPFSQKVYFNIDSRSVGLDLLS 840 + A T +G G S +V I + + ++S Sbjct: 1254 VTASTRVGEGK-SSRVSSQITTNRIPARIIS 1283 Score = 46.8 bits (106), Expect = 0.004 Identities = 38/129 (29%), Positives = 57/129 (44%), Gaps = 5/129 (3%) Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP-LGRV 249 S I T +I + GP VV S+VT C G P + W +S L Sbjct: 1270 SQITTNRIPARIISFGGP--VVRPWRSTVTLPCTAVGKPKRE--WFKSDVALRQGGLHNS 1325 Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309 ++LD G L + ++ LAD G YSC+ +N +G + L V PP+ + + S + Sbjct: 1326 QLLDSGDLIISSLQLADGGNYSCQVDNGIGTDRLTHTLIVQVPPTAPVLYVTSATSSSIL 1385 Query: 310 ARFTCTATG 318 + C TG Sbjct: 1386 MHWKCGFTG 1394 Score = 45.2 bits (102), Expect = 0.011 Identities = 80/343 (23%), Positives = 125/343 (36%), Gaps = 28/343 (8%) Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG--DTVVLECLPPRGSPEPNV 140 +W A+ G +S + + R R+ + TV L C G P+ Sbjct: 1252 FWVTASTRVGEGKSSRVSSQITTNRIPARIISFGGPVVRPWRSTVTLPCTAV-GKPKRE- 1309 Query: 141 YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200 W K+ L G L+D G+L+I + D G Y C N GT + TL + + Sbjct: 1310 -WFKSDVALRQGGLHNSQLLDSGDLIISSLQLADGGNYSCQVDNGIGT-DRLTHTLIVQV 1367 Query: 201 KPYLITGPE-DVVAQTGSSVTFQCR---VGGDPLP--DVLWRRSAGG-GNMPLGRVKVLD 253 P T P V + T SS+ + G P+ + +RR+ G M L R Sbjct: 1368 PP---TAPVLYVTSATSSSILMHWKCGFTGNAPITGYTLFYRRANGNTDEMQLSR----H 1420 Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313 S L ++ + A+N VG S L V P S + + N Sbjct: 1421 ASSHELKGLMCGSTYQIHLSAQNKVGTSPTSTILHVRTQGQSPGHPASTALLAPNSTSLL 1480 Query: 314 CTATGRPE---PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370 P+ P +++ ++ P + + + IN+ + + + Sbjct: 1481 VRLHSWPDNGCPLLYFVLQYRAVTDDP--DAEWVLVSNALKPQRRIVINNLQPS-TLYQL 1537 Query: 371 VCSAVNYAGSSFVR-GKLTVTSDDDRPPP-IITNGPSNQTLPI 411 A N AG S +T+T D D PPP I+ G S QT I Sbjct: 1538 RMEAHNVAGISQAEFNFVTLTKDGDPPPPEIMHRGRSGQTTVI 1580 Score = 44.4 bits (100), Expect = 0.019 Identities = 32/121 (26%), Positives = 51/121 (42%), Gaps = 4/121 (3%) Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQN--HRRNVTNDGTLVLKDLDKSDSGTYTC 467 P +S PCTA+ P+ W+ AL Q H + + G L++ L +D G Y+C Sbjct: 1291 PWRSTVTLPCTAVGKPKR--EWFKSDVALRQGGLHNSQLLDSGDLIISSLQLADGGNYSC 1348 Query: 468 VASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527 + G + L+V P + + +A SS+ T N T TL + + Sbjct: 1349 QVDNGIGTDRLTHTLIVQVPPTAPVLYVTSATSSSILMHWKCGFTGNAPITGYTLFYRRA 1408 Query: 528 N 528 N Sbjct: 1409 N 1409 Score = 38.3 bits (85), Expect = 1.3 Identities = 67/304 (22%), Positives = 108/304 (35%), Gaps = 25/304 (8%) Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK-VLDDGSLRLDNVILAD 266 P V S C G P P V W + G + V+ VL +G+L L A Sbjct: 4 PGRVEFSNSSGGWLDCSASGSPQPTVDWVHADGSAVTEIHGVRRVLRNGTLVLMPFAAAA 63 Query: 267 EGE------YSCEAENSVGA-VSASGYLTVYDPPSINLSPNSVNVESGNVARFTC---TA 316 + Y C A NSVG VS + + + ++ G A C T Sbjct: 64 YHQDVHNTIYRCIASNSVGRIVSRDVQVRAVVAQAYKVDVEVLSAARGCTAILRCVVPTF 123 Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRD-KYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375 + W V I+P + D K+H + L I++ ++D + C ++ Sbjct: 124 VKELVRVVSW-VHEPAIYIYPSLQGDGKFHLLPTGE----LLIHNLQESDESQSFRCRSM 178 Query: 376 NYAGSSFVRG---KLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432 + V +L + S P + ++ + AV C A P P +W+ Sbjct: 179 HRLTRQVVVSSPTRLRINSHRGIISPSVVEHTAHVQVSQDEGAVLLCVAQGCPSPEYSWF 238 Query: 433 FEGEA----LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPI 488 A ++ R + L ++ + DSG Y C A + G+ L V +PI Sbjct: 239 THNGAGPLPVLSGPRVRLLGP-ILAIEAVTGEDSGVYKCTAGNVGGEASAELRLTVATPI 297 Query: 489 NPNI 492 I Sbjct: 298 QVEI 301 >UniRef50_UPI000065D4F5 Cluster: Homolog of Danio rerio "Novel hemicentin protein; n=1; Takifugu rubripes|Rep: Homolog of Danio rerio "Novel hemicentin protein - Takifugu rubripes Length = 2555 Score = 159 bits (386), Expect = 4e-37 Identities = 143/486 (29%), Positives = 220/486 (45%), Gaps = 49/486 (10%) Query: 4 DY-VTSGEAPYII--EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDT-HR 58 DY +T +P I+ E P +V+ + TL CRA G+P+P + W K GV V SD+ H Sbjct: 1418 DYALTVQVSPTILDSEHPSEVSAPMGEDMTLECRAAGNPTPHLSWLKDGVTVEGSDSRHI 1477 Query: 59 SILPAGG-LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEP 114 + P G L LR + D+G Y C A + G +++ TL V V + E + P Sbjct: 1478 GVTPEGSTLTLLRLS----PDDSGTYTCLAVSPAG-RQTKIYTLFVLVPPSISGETTV-P 1531 Query: 115 ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTD 174 Q Q V LEC GSP P + W KNG LL +R+ D L I + +D Sbjct: 1532 REVQVTQDGAVTLEC-QAVGSPPPQISWLKNGHPLLLSSRTRLLSAD-SVLRISPVQLSD 1589 Query: 175 AGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL 234 +G Y C+AR+ AG E + +++ ++P I GS VT C G P P + Sbjct: 1590 SGVYTCMARSQAGLAELSY-DVQVQVEPVTIV--------QGSLVTLSCEARGVPPPTLT 1640 Query: 235 WRRSAGGGNMPLGRVKVLD--DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292 W + G + L R +LD + L+L +V +D G YSC A N G+ + + LTV +P Sbjct: 1641 WLKD--GQPLSLHRNLLLDGQETRLQLPDVGPSDAGLYSCVASNQAGSSTKTFNLTVLEP 1698 Query: 293 PSI--NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350 P + + SP + + + C+ATG P PT+ W +G+ P RD F Sbjct: 1699 PKMTGSSSPEELFIAVNSPLELECSATGVPPPTLTWLKDGH-----PLERRDIVQEDGHF 1753 Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTL 409 ++ + + D C A + AG + V PP ++ ++ T+ Sbjct: 1754 VRISKVQVEDA------GLYTCLASSLAGEDGKNHWIRV----QVPPTLLGSDEVRTVTV 1803 Query: 410 PIKSMAVFPCTAICTPEPIIAWY-FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468 P+ C A P P I WY E + + + + L ++++ DSG Y+CV Sbjct: 1804 PVNGHLTLECLADSDPAPDIEWYKDEVKVQLGGRVQQLAGGQYLEIQEVKPEDSGLYSCV 1863 Query: 469 ASSRHG 474 ++ G Sbjct: 1864 VTNMAG 1869 Score = 156 bits (379), Expect = 3e-36 Identities = 137/470 (29%), Positives = 209/470 (44%), Gaps = 46/470 (9%) Query: 17 QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV 76 + L+ T+ H +L C+A G P P+I W K G + S G L Sbjct: 1343 ESLNYTLGSH--VSLPCQASGFPVPSITWLKDGTPIESSLQWQWSIRGSRLELGPL---A 1397 Query: 77 HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLECLPPRGS 135 + G+Y C A NS G A+ ++ L V V E S+ SA G+ + LEC G+ Sbjct: 1398 LAHGGLYTCLAKNSEGQAQ-KDYALTVQVSPTILDSEHPSEVSAPMGEDMTLECRAA-GN 1455 Query: 136 PEPNVYWKKNGQTLLFDGDSRMHL---VDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192 P P++ W K+G T+ +G H+ +G L + D+G Y C+A + AG R++ Sbjct: 1456 PTPHLSWLKDGVTV--EGSDSRHIGVTPEGSTLTLLRLSPDDSGTYTCLAVSPAG-RQTK 1512 Query: 193 IATLKIHIKPYL---ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249 I TL + + P + T P +V +VT +C+ G P P + W ++ G + R Sbjct: 1513 IYTLFVLVPPSISGETTVPREVQVTQDGAVTLECQAVGSPPPQISWLKN-GHPLLLSSRT 1571 Query: 250 KVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGN 308 ++L D LR+ V L+D G Y+C A + G S YD + + V + G+ Sbjct: 1572 RLLSADSVLRISPVQLSDSGVYTCMARSQAGLAELS-----YD---VQVQVEPVTIVQGS 1623 Query: 309 VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV-TVLTINDTDKNDSR 367 + +C A G P PT+ W +G + H + DG T L + D +D+ Sbjct: 1624 LVTLSCEARGVPPPTLTWLKDGQPLSL---------HRNLLLDGQETRLQLPDVGPSDA- 1673 Query: 368 NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIKSMAVFPCTAICTPE 426 C A N AGSS LTV PP + ++ P + + S C+A P Sbjct: 1674 GLYSCVASNQAGSSTKTFNLTVLE----PPKMTGSSSPEELFIAVNSPLELECSATGVPP 1729 Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHGK 475 P + W +G L R V DG V + + D+G YTC+ASS G+ Sbjct: 1730 PTLTWLKDGHPL--ERRDIVQEDGHFVRISKVQVEDAGLYTCLASSLAGE 1777 Score = 148 bits (358), Expect = 1e-33 Identities = 137/494 (27%), Positives = 210/494 (42%), Gaps = 59/494 (11%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS--DTHRSILPAGGLFFL 69 P I + VT + PA L C G P P + W KGG + S T+R +LP G L Sbjct: 2079 PSIEDDVTAVTAVKLAPAVLPCHVHGRPQPTVFWTKGGAKLSSRGGTYR-VLPTG---LL 2134 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 T + S AG Y C A NS G A ++ +L V E R E Q VL C Sbjct: 2135 EIT-SVLPSHAGRYTCSARNSAGVAH-KHVSLSVQE-SPEIRPMAEEVQVVLHHGTVLPC 2191 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189 +G P P++ W++ G + R+ L+ G L DAG YQC+A+N AG Sbjct: 2192 -EAQGFPRPSISWQREGVPIATG--HRLSLLSNGALKFSRVTLGDAGTYQCLAKNEAGAA 2248 Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGR 248 L +H+ P + ++ G C G P P + W ++ N+P G+ Sbjct: 2249 VGQ-TKLVLHVPPLISPAQTELSVIQGFQALLSCAAQGSPDPKISWEKNGSPVPNIP-GK 2306 Query: 249 VKVLDDGSLRLDN-----VILA---------------------DEGEYSCEAENSVGAVS 282 VL G L ++ +ILA D G ++C A N+ G+ Sbjct: 2307 YTVLRSGELIIERAEVCLLILAALRLEAHQNPLNQFWFLTQPADAGLFTCVATNAAGSAR 2366 Query: 283 ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRD 342 L++ P+ P V + G +C A G P P + W+V + G + D Sbjct: 2367 QDRRLSINMRPAFKELPGDVTLNKGQSLALSCHAQGTPSPVISWTVNNSPR---QGAAVD 2423 Query: 343 KYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT- 401 + G + L I + +D+ T VC A N GS VR T++ R PP++ Sbjct: 2424 E-------AGRSSLIIENVTTSDA-GTYVCVAENRVGS--VR---TLSFVRVREPPVLKG 2470 Query: 402 NGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLD-KS 460 + +QT+ S + C P P++ W +G AL+++HR +G+LV+ ++ + Sbjct: 2471 DAHMSQTVIQGSSTILDCPIHGDPSPVLQWLRDGNALLRSHRIQALLNGSLVIYSVNVNT 2530 Query: 461 DSGTYTCVASSRHG 474 G Y C+A + G Sbjct: 2531 HEGEYQCLAENEAG 2544 Score = 147 bits (356), Expect = 2e-33 Identities = 132/496 (26%), Positives = 197/496 (39%), Gaps = 49/496 (9%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRS--ILPAGGLFF 68 P I P +VTV A L+C G PSP + W + G L VS + +L +G L Sbjct: 1973 PSISPGPFNVTVTSGIRAVLSCETTGIPSPKVSWKRNGTPLDVSQLSGAFRLLSSGSLVL 2032 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARS------RNATLHVAVLREEFRLEPESKQSAQG 122 L ++ D G + C A N G R ++ V V F P S + Sbjct: 2033 LSPSN----EDEGYFECTAVNEAGEERRVIEVILQDGQTDVCVFM--FCSVPPSIEDDVT 2086 Query: 123 DTVVLECLPP------RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAG 176 ++ P G P+P V+W K G L G + ++ G L I + AG Sbjct: 2087 AVTAVKLAPAVLPCHVHGRPQPTVFWTKGGAKLSSRGGT-YRVLPTGLLEITSVLPSHAG 2145 Query: 177 RYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 RY C ARN+AG ++ L + P + E+V C G P P + W+ Sbjct: 2146 RYTCSARNSAGVAHKHVS-LSVQESPEIRPMAEEVQVVLHHGTVLPCEAQGFPRPSISWQ 2204 Query: 237 RSAGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295 R G + G R+ +L +G+L+ V L D G Y C A+N GA L ++ PP I Sbjct: 2205 RE--GVPIATGHRLSLLSNGALKFSRVTLGDAGTYQCLAKNEAGAAVGQTKLVLHVPPLI 2262 Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355 + + ++V G A +C A G P+P + W G+ PG + + V Sbjct: 2263 SPAQTELSVIQGFQALLSCAAQGSPDPKISWEKNGSPVPNIPGKYTVLRSGELIIERAEV 2322 Query: 356 ---------LTINDTDKND--------SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398 L + N C A N AGS+ +L++ P Sbjct: 2323 CLLILAALRLEAHQNPLNQFWFLTQPADAGLFTCVATNAAGSARQDRRLSINM-----RP 2377 Query: 399 IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLD 458 P + TL C A TP P+I+W Q + +L+++++ Sbjct: 2378 AFKELPGDVTLNKGQSLALSCHAQGTPSPVISWTVNNSPR-QGAAVDEAGRSSLIIENVT 2436 Query: 459 KSDSGTYTCVASSRHG 474 SD+GTY CVA +R G Sbjct: 2437 TSDAGTYVCVAENRVG 2452 Score = 146 bits (353), Expect = 4e-33 Identities = 135/483 (27%), Positives = 198/483 (40%), Gaps = 40/483 (8%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80 VTV + TL C A P+P I WYK V V L G ++ D+ Sbjct: 1801 VTVPVNGHLTLECLADSDPAPDIEWYKDEVKVQLGGRVQQLAGGQYLEIQEVKPE---DS 1857 Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDTVVLECLPPRGSPEPN 139 G+Y C TN G S + V +L E S+ + G +L C S Sbjct: 1858 GLYSCVVTNMAG---SSSLFFTVEILLPPIIRESSSEVTTHIGQDALLPCEVEEES-HAT 1913 Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199 V W+K+G + D+R L+ G+L I + +DAGRY C N AG+ + L++ Sbjct: 1914 VTWRKDGFPIT--QDNRYTLLSEGSLRIHGVQLSDAGRYYCTVSNQAGSDHRGVE-LRVF 1970 Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL--GRVKVLDDGSL 257 + P + GP +V +G C G P P V W+R+ ++ G ++L GSL Sbjct: 1971 VGPSISPGPFNVTVTSGIRAVLSCETTGIPSPKVSWKRNGTPLDVSQLSGAFRLLSSGSL 2030 Query: 258 RLDNVILADEGEYSCEAENSVG-------AVSASG------YLTVYDPPSINLSPNSVNV 304 L + DEG + C A N G + G ++ PPSI +V Sbjct: 2031 VLLSPSNEDEGYFECTAVNEAGEERRVIEVILQDGQTDVCVFMFCSVPPSIEDDVTAVTA 2090 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 A C GRP+PT+FW+ G + G R T + + +VL + Sbjct: 2091 VKLAPAVLPCHVHGRPQPTVFWTKGGAKLSSRGGTYR--VLPTGLLEITSVLP-----SH 2143 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424 R T CSA N AG + L+V P I + + V PC A Sbjct: 2144 AGRYT--CSARNSAGVAHKHVSLSVQES-----PEIRPMAEEVQVVLHHGTVLPCEAQGF 2196 Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 P P I+W EG + HR ++ ++G L + D+GTY C+A + G V L++ Sbjct: 2197 PRPSISWQREGVPIATGHRLSLLSNGALKFSRVTLGDAGTYQCLAKNEAGAAVGQTKLVL 2256 Query: 485 DSP 487 P Sbjct: 2257 HVP 2259 Score = 136 bits (329), Expect = 3e-30 Identities = 110/392 (28%), Positives = 161/392 (41%), Gaps = 15/392 (3%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 EAP ++ P +R + C A GSP P + W G +L+ + +I G L Sbjct: 82 EAPSVVIHPQSRVFSRGEEIRFVCSASGSPPPQLFWSHGNMLLTNRQRLNINHYGVL--- 138 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 G + DAG Y C ATN G A S++ +L + R+ ++ + G VLEC Sbjct: 139 -TIKGALPEDAGNYTCLATNEAGVA-SQSVSLTFSEA-PRIRVTQQAIHVSVGADAVLEC 195 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189 G+P P V W K G+ + V G+L I+ ++ DAGRY C+A + AGT Sbjct: 196 -QATGAPPPLVRWFK-GEFEVGSTPFAGQDVHHGDLHIRGVQEVDAGRYTCVASSPAGTA 253 Query: 190 ESAIATLKIHIKPYLI--TGPEDVV---AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 + LK+ P +I T + V + G+ V C G+P P V W R+ Sbjct: 254 TGTVI-LKVGAMPKIIGVTSNDKTVKMAVEVGTEVVLPCEAQGNPSPLVTWSRNGHPIPP 312 Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304 VL GSLR+ +V L D Y+C AEN G VS S L + P I + + Sbjct: 313 VTAGFTVLPSGSLRITDVRLIDSKRYTCTAENPAGNVSLSYNLHIQAKPRIQPAATLLKA 372 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 G C G P P + W G + + + H + D T + Sbjct: 373 RIGQTVTLPCVVQGEPSPEVTWFHNG-LPVGIKNATPLRIHQAKLGDQGTYRCVATNSAG 431 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP 396 + I + S+F + V S RP Sbjct: 432 QETSEIKLDILVRRNSAFAHSFVFVNSGSPRP 463 Score = 134 bits (325), Expect = 1e-29 Identities = 135/505 (26%), Positives = 208/505 (41%), Gaps = 49/505 (9%) Query: 17 QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV 76 + LDV + P +L+C + P P + W+K G ++S +LP G + + Sbjct: 945 EKLDVVLGH--PVSLSCESNAIPPPKLSWHKDGQKLLSGDGVVLLPGGQVLQIARVR--- 999 Query: 77 HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136 DAG Y C+A N G + LH+ E+F E + TVVL C G P Sbjct: 1000 KDDAGRYTCQAVNEAGEDH-MHFELHIL---EQFM---EEIAAVVNSTVVLHC-DVTGQP 1051 Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196 P V W ++GQ + D ++ DG L + + +D Y C+A N GT E + +L Sbjct: 1052 TPAVSWLRDGQPVQLDPQHQIS-KDGTQLQLLSVQVSDMAGYLCVAENKVGTVEK-LFSL 1109 Query: 197 KIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR-VKVLD 253 I + P I+G E+ G + + C V P P++ W R G + G V +L Sbjct: 1110 TIQVPP-RISGHMEEETSVIEGHTASLLCDVQAYPPPEITWTRD--GQILAFGTGVHILP 1166 Query: 254 DGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS----INLSPNSVNVESGN 308 G L+L L D G+Y C A NS G S L+VY P+ ++ + + V + G+ Sbjct: 1167 GGQMLQLPRARLEDAGQYVCTATNSAGQDQKSILLSVYVRPTMKPRLDAASDLVTPQVGS 1226 Query: 309 VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV-------FDGVTVLTINDT 361 +C G PEP + W G + G D+Y V FD + + Sbjct: 1227 SVTLSCETHGVPEPEVTWYKNGLQLAPRNGFEMDRYQLEIVGVQVRKTFDVTHLRLLECC 1286 Query: 362 DKNDSRNTIVCSAVNYA-----GSSFVRGKLTVTSDDDRP-------PPIITNGP-SNQT 408 +DSR C + G ++ V DR PP++ + Sbjct: 1287 QISDSRLNCQCGEFIFGSQVADGGTYTCKVSNVAGQVDRTFRLTVHVPPVLEGSLWESLN 1346 Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTC 467 + S PC A P P I W +G + + + + G+ L L L + G YTC Sbjct: 1347 YTLGSHVSLPCQASGFPVPSITWLKDGTPIESSLQWQWSIRGSRLELGPLALAHGGLYTC 1406 Query: 468 VASSRHGKYVWSGALLVDSPINPNI 492 +A + G+ AL V ++P I Sbjct: 1407 LAKNSEGQAQKDYALTVQ--VSPTI 1429 Score = 132 bits (319), Expect = 6e-29 Identities = 119/401 (29%), Positives = 169/401 (42%), Gaps = 51/401 (12%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E+P I +V V H L C A G P P+I W + GV + + S+L G L F Sbjct: 2168 ESPEIRPMAEEVQVVLHHGTVLPCEAQGFPRPSISWQREGVPIATGHRLSLLSNGALKFS 2227 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNA-TLHVAVLREEFRLEPESKQSAQGDTVVLE 128 R T G DAG Y C A N G A + LHV L + E QG +L Sbjct: 2228 RVTLG----DAGTYQCLAKNEAGAAVGQTKLVLHVPPLISPAQTE---LSVIQGFQALLS 2280 Query: 129 CLPPRGSPEPNVYWKKNGQ---------TLLFDGDSRMHLVDGGNLVIQ----DARQT-- 173 C +GSP+P + W+KNG T+L G+ + + L++ +A Q Sbjct: 2281 CAA-QGSPDPKISWEKNGSPVPNIPGKYTVLRSGELIIERAEVCLLILAALRLEAHQNPL 2339 Query: 174 ----------DAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223 DAG + C+A NAAG+ L I+++P P DV G S+ C Sbjct: 2340 NQFWFLTQPADAGLFTCVATNAAGSARQD-RRLSINMRPAFKELPGDVTLNKGQSLALSC 2398 Query: 224 RVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAV 281 G P P + W + N P V + G SL ++NV +D G Y C AEN VG+V Sbjct: 2399 HAQGTPSPVISWTVN----NSPRQGAAVDEAGRSSLIIENVTTSDAGTYVCVAENRVGSV 2454 Query: 282 SASGYLTVYDPPSINLSPN-SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340 ++ V +PP + + S V G+ C G P P + W +GN + Sbjct: 2455 RTLSFVRVREPPVLKGDAHMSQTVIQGSSTILDCPIHGDPSPVLQWLRDGNALL------ 2508 Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381 + A+ +G L I + N C A N AG++ Sbjct: 2509 -RSHRIQALLNG--SLVIYSVNVNTHEGEYQCLAENEAGTA 2546 Score = 131 bits (317), Expect = 1e-28 Identities = 124/464 (26%), Positives = 191/464 (41%), Gaps = 40/464 (8%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRS-ILPAGGLFFLRATHGRVHS 78 +VT + A L+C+ GS + WY+ G + + T RS +LP L G Sbjct: 1 NVTSSVGAVAVLSCKVEGSVRHNLTWYRAGRAIGAHTGRSKVLPDSSL----QISGVQIQ 56 Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138 DAG Y C ATN++G +R LHV + P+S+ ++G+ + C GSP P Sbjct: 57 DAGEYHCVATNAHGDSRI-IVWLHVPE-APSVVIHPQSRVFSRGEEIRFVC-SASGSPPP 113 Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198 ++W +L R+++ G L I+ A DAG Y C+A N AG ++ +L Sbjct: 114 QLFWSHG--NMLLTNRQRLNINHYGVLTIKGALPEDAGNYTCLATNEAGVASQSV-SLTF 170 Query: 199 HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW-RRSAGGGNMPLGRVKVLDDGSL 257 P + + + G+ +C+ G P P V W + G+ P V G L Sbjct: 171 SEAPRIRVTQQAIHVSVGADAVLECQATGAPPPLVRWFKGEFEVGSTPFAGQDV-HHGDL 229 Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-----NLSPNSVNVESGNVARF 312 + V D G Y+C A + G + + L V P I N + VE G Sbjct: 230 HIRGVQEVDAGRYTCVASSPAGTATGTVILKVGAMPKIIGVTSNDKTVKMAVEVGTEVVL 289 Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372 C A G P P + WS G+ P ++ T + G L I D DS+ C Sbjct: 290 PCEAQGNPSPLVTWSRNGHP---IPPVTAG---FTVLPSG--SLRITDVRLIDSKR-YTC 340 Query: 373 SAVNYAGSSFVRGKLTVTSDDD-RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431 +A N AG+ + L + + +P + QT+ + PC P P + W Sbjct: 341 TAENPAGNVSLSYNLHIQAKPRIQPAATLLKARIGQTVTL------PCVVQGEPSPEVTW 394 Query: 432 YFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 + G + + N L + D GTY CVA++ G+ Sbjct: 395 FHNGLPV------GIKNATPLRIHQAKLGDQGTYRCVATNSAGQ 432 Score = 130 bits (314), Expect = 2e-28 Identities = 119/437 (27%), Positives = 173/437 (39%), Gaps = 35/437 (8%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I E +VT Q A L C + W K G + D ++L G L Sbjct: 1883 PIIRESSSEVTTHIGQDALLPCEVEEESHATVTWRKDGFPITQDNRYTLLSEGSL----R 1938 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131 HG SDAG Y+C +N G+ R L V V P + G VL C Sbjct: 1939 IHGVQLSDAGRYYCTVSNQAGSDH-RGVELRVFV-GPSISPGPFNVTVTSGIRAVLSC-E 1995 Query: 132 PRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190 G P P V WK+NG L + L+ G+LV+ D G ++C A N AG Sbjct: 1996 TTGIPSPKVSWKRNGTPLDVSQLSGAFRLLSSGSLVLLSPSNEDEGYFECTAVNEAGEER 2055 Query: 191 SAIATL------KIHIKPYLITGP---EDVVAQTG---SSVTFQCRVGGDPLPDVLWRRS 238 I + + + + P +DV A T + C V G P P V W + Sbjct: 2056 RVIEVILQDGQTDVCVFMFCSVPPSIEDDVTAVTAVKLAPAVLPCHVHGRPQPTVFWTKG 2115 Query: 239 AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298 + G +VL G L + +V+ + G Y+C A NS G L+V + P I Sbjct: 2116 GAKLSSRGGTYRVLPTGLLEITSVLPSHAGRYTCSARNSAGVAHKHVSLSVQESPEIRPM 2175 Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358 V V + C A G P P++ W EG I G + + + +G L Sbjct: 2176 AEEVQVVLHHGTVLPCEAQGFPRPSISWQREG--VPIATG-----HRLSLLSNG--ALKF 2226 Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418 + D+ T C A N AG++ + KL + PP+I+ + ++ A+ Sbjct: 2227 SRVTLGDA-GTYQCLAKNEAGAAVGQTKLVL-----HVPPLISPAQTELSVIQGFQALLS 2280 Query: 419 CTAICTPEPIIAWYFEG 435 C A +P+P I+W G Sbjct: 2281 CAAQGSPDPKISWEKNG 2297 Score = 125 bits (301), Expect = 8e-27 Identities = 132/475 (27%), Positives = 192/475 (40%), Gaps = 43/475 (9%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 +T EAP I + V+ A L C+A G+P P +RW+KG V S G Sbjct: 168 LTFSEAPRIRVTQQAIHVSVGADAVLECQATGAPPPLVRWFKGEFEVGSTPFAGQDVHHG 227 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---- 121 +R G DAG Y C A++ GTA + L V + + + K Sbjct: 228 DLHIR---GVQEVDAGRYTCVASSPAGTA-TGTVILKVGAMPKIIGVTSNDKTVKMAVEV 283 Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181 G VVL C +G+P P V W +NG + + ++ G+L I D R D+ RY C Sbjct: 284 GTEVVLPC-EAQGNPSPLVTWSRNGHPIP-PVTAGFTVLPSGSLRITDVRLIDSKRYTCT 341 Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241 A N AG S L I KP + + A+ G +VT C V G+P P+V W + Sbjct: 342 AENPAG-NVSLSYNLHIQAKPRIQPAATLLKARIGQTVTLPCVVQGEPSPEVTWFHN--- 397 Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301 +P+G + + LR+ L D+G Y C A NS G ++ L I + NS Sbjct: 398 -GLPVG---IKNATPLRIHQAKLGDQGTYRCVATNSAGQETSEIKL------DILVRRNS 447 Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361 S F +G P P + W G I P S + DG V+ Sbjct: 448 AFAHS-----FVFVNSGSPRPKIRWFRNGLE--IHPEQS----DFSVGEDGALVIRAASA 496 Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN-GPSNQTLPIKSMAVFPCT 420 + C A N AGS + +L V + PP I + P N T+ +K C Sbjct: 497 SHS---GDFTCVATNEAGSVERKTRLKV----NVPPEIQDDTQPLNLTVTLKQPLTLGCD 549 Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 A P P I W +G + + L + + +G ++C A + G+ Sbjct: 550 AFGIPSPTITWSKDGHPVDTPGVYLQNGNRMLRIYRVQPEHAGRFSCTAQNSAGE 604 Score = 120 bits (288), Expect = 3e-25 Identities = 136/500 (27%), Positives = 196/500 (39%), Gaps = 56/500 (11%) Query: 17 QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV 76 QPL++TV QP TL C A G PSP I W K G V DT L G LR RV Sbjct: 532 QPLNLTVTLKQPLTLGCDAFGIPSPTITWSKDGHPV--DTPGVYLQNGNR-MLRIY--RV 586 Query: 77 HSD-AGVYWCEATNSYGTARSRNATL----HVAVLREEFRLEPESKQSAQ-----GDTVV 126 + AG + C A NS G AR + + H+ R S +A+ G V Sbjct: 587 QPEHAGRFSCTAQNSAGEARREYSIVVQGKHIKQPPLTTRTLTMSVSNAELTVALGQEVE 646 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCIARNA 185 +C RG P P V W ++G+ L DGD + DG L ++ R D G YQC+A N Sbjct: 647 FQC-QVRGKPPPRVEWSRDGEVLSRDGDPHVEFHEDGQVLKVKAVRLRDQGIYQCLASNN 705 Query: 186 AGTRESAI-ATLKIH------IKPYLITGP---EDVVAQTGSSVTFQCRVGGDPLPDVLW 235 AGT+ T+++ + P I GP +V G S C V G P P + W Sbjct: 706 AGTQMRQFRLTVQVRTIVVVCLSPPTIKGPSETSEVSVVLGFSTLLSCDVEGSPTPSITW 765 Query: 236 RRSAGGGNMPLGRVKVL----DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291 + N P+ L +LRL +V G Y+C A N G L V Sbjct: 766 LKD----NQPIVSSPQLTYTRGGQALRLGSVQGDSTGLYTCRATNPAGTAIKHYSLVVLV 821 Query: 292 PPSIN-----LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI--IFPGMSRDKY 344 PP I + V +C G PEP + W +G + G+ + Sbjct: 822 PPQIEGDSPVFGTHEEKVRMNGSLTLSCMTKGFPEPKIQWFKDGQLLTGSVHTGIQELGH 881 Query: 345 -----HATAVFDGVTVLTINDT---DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP 396 + V +G + ++ DK D TI V + ++ DD Sbjct: 882 SLLIENTMLVHEGQYTCVVTNSAGEDKRDFHVTIQVPPVFHRVTNREAAWGLGHEGDDED 941 Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLK 455 + + + C + P P ++W+ +G+ L+ + G L + Sbjct: 942 DTV-----EKLDVVLGHPVSLSCESNAIPPPKLSWHKDGQKLLSGDGVVLLPGGQVLQIA 996 Query: 456 DLDKSDSGTYTCVASSRHGK 475 + K D+G YTC A + G+ Sbjct: 997 RVRKDDAGRYTCQAVNEAGE 1016 Score = 119 bits (286), Expect = 6e-25 Identities = 121/465 (26%), Positives = 189/465 (40%), Gaps = 43/465 (9%) Query: 37 GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96 GSP P IRW++ G+ + + + G +RA S +G + C ATN G+ Sbjct: 459 GSPRPKIRWFRNGLEIHPEQSDFSVGEDGALVIRAASA---SHSGDFTCVATNEAGSVE- 514 Query: 97 RNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155 R L V V E + +P + + L C G P P + W K+G + G Sbjct: 515 RKTRLKVNVPPEIQDDTQPLNLTVTLKQPLTLGC-DAFGIPSPTITWSKDGHPVDTPG-- 571 Query: 156 RMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGT--RESAIATLKIHIK-PYLIT----- 206 ++L +G ++ I + AGR+ C A+N+AG RE +I HIK P L T Sbjct: 572 -VYLQNGNRMLRIYRVQPEHAGRFSCTAQNSAGEARREYSIVVQGKHIKQPPLTTRTLTM 630 Query: 207 --GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGS-LRLDNV 262 ++ G V FQC+V G P P V W R + V+ +DG L++ V Sbjct: 631 SVSNAELTVALGQEVEFQCQVRGKPPPRVEWSRDGEVLSRDGDPHVEFHEDGQVLKVKAV 690 Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVY---------DPPSIN--LSPNSVNVESGNVAR 311 L D+G Y C A N+ G LTV PP+I + V+V G Sbjct: 691 RLRDQGIYQCLASNNAGTQMRQFRLTVQVRTIVVVCLSPPTIKGPSETSEVSVVLGFSTL 750 Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371 +C G P P++ W + + P ++ + G L + + DS Sbjct: 751 LSCDVEGSPTPSITWLKDNQPIVSSPQLTYTR--------GGQALRLGSV-QGDSTGLYT 801 Query: 372 CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431 C A N AG++ L V G + + + C PEP I W Sbjct: 802 CRATNPAGTAIKHYSLVVLVPPQIEGDSPVFGTHEEKVRMNGSLTLSCMTKGFPEPKIQW 861 Query: 432 YFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGK 475 + +G+ L + + G +L++++ G YTCV ++ G+ Sbjct: 862 FKDGQLLTGSVHTGIQELGHSLLIENTMLVHEGQYTCVVTNSAGE 906 Score = 118 bits (284), Expect = 1e-24 Identities = 117/421 (27%), Positives = 175/421 (41%), Gaps = 40/421 (9%) Query: 78 SDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136 +D G Y C+ +N G R+ T+HV + E E S G V L C G P Sbjct: 1307 ADGGTYTCKVSNVAGQVDRTFRLTVHVPPVLEGSLWE--SLNYTLGSHVSLPC-QASGFP 1363 Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196 P++ W K+G T + + G L + G Y C+A+N+ G + A L Sbjct: 1364 VPSITWLKDG-TPIESSLQWQWSIRGSRLELGPLALAHGGLYTCLAKNSEGQAQKDYA-L 1421 Query: 197 KIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR-VKVLD 253 + + P ++ P +V A G +T +CR G+P P + W + R + V Sbjct: 1422 TVQVSPTILDSEHPSEVSAPMGEDMTLECRAAGNPTPHLSWLKDGVTVEGSDSRHIGVTP 1481 Query: 254 DGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN---LSPNSVNVESGNV 309 +GS L L + D G Y+C A + G + L V PPSI+ P V V Sbjct: 1482 EGSTLTLLRLSPDDSGTYTCLAVSPAGRQTKIYTLFVLVPPSISGETTVPREVQVTQDGA 1541 Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369 C A G P P + W G+ ++ SR T + +VL I+ +DS Sbjct: 1542 VTLECQAVGSPPPQISWLKNGHPLLL---SSR-----TRLLSADSVLRISPVQLSDS-GV 1592 Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429 C A + AG + + + V + P I G S+ C A P P + Sbjct: 1593 YTCMARSQAGLAELSYDVQVQVE----PVTIVQG---------SLVTLSCEARGVPPPTL 1639 Query: 430 AWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486 W +G+ L + RN+ DG L L D+ SD+G Y+CVAS++ G + L V Sbjct: 1640 TWLKDGQPL--SLHRNLLLDGQETRLQLPDVGPSDAGLYSCVASNQAGSSTKTFNLTVLE 1697 Query: 487 P 487 P Sbjct: 1698 P 1698 Score = 97.5 bits (232), Expect = 2e-18 Identities = 69/232 (29%), Positives = 109/232 (46%), Gaps = 14/232 (6%) Query: 13 YIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 +I+EQ ++ + + L+C G P+PA+ W + G V D I G L + Sbjct: 1024 HILEQFMEEIAAVVNSTVVLHCDVTGQPTPAVSWLRDGQPVQLDPQHQISKDGTQLQLLS 1083 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131 SD Y C A N GT + R +E E+ +G T L C Sbjct: 1084 VQV---SDMAGYLCVAENKVGTVEKLFSLTIQVPPRISGHMEEETSV-IEGHTASLLC-D 1138 Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRE 190 + P P + W ++GQ L F + +H++ GG ++ + AR DAG+Y C A N+AG + Sbjct: 1139 VQAYPPPEITWTRDGQILAFG--TGVHILPGGQMLQLPRARLEDAGQYVCTATNSAGQDQ 1196 Query: 191 SAIATLKIHIKPYL---ITGPEDVVA-QTGSSVTFQCRVGGDPLPDVLWRRS 238 +I L ++++P + + D+V Q GSSVT C G P P+V W ++ Sbjct: 1197 KSIL-LSVYVRPTMKPRLDAASDLVTPQVGSSVTLSCETHGVPEPEVTWYKN 1247 Score = 93.5 bits (222), Expect = 3e-17 Identities = 86/306 (28%), Positives = 143/306 (46%), Gaps = 39/306 (12%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFF-- 68 P I +++V + A L+C A GSP P I W K G V + + ++L +G L Sbjct: 2260 PLISPAQTELSVIQGFQALLSCAAQGSPDPKISWEKNGSPVPNIPGKYTVLRSGELIIER 2319 Query: 69 -------LRATHGRVH-------------SDAGVYWCEATNSYGTAR-SRNATLHVAVLR 107 L A H +DAG++ C ATN+ G+AR R +++ +R Sbjct: 2320 AEVCLLILAALRLEAHQNPLNQFWFLTQPADAGLFTCVATNAAGSARQDRRLSIN---MR 2376 Query: 108 EEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVI 167 F+ P +G ++ L C +G+P P + W N + + +L+I Sbjct: 2377 PAFKELPGDVTLNKGQSLALSC-HAQGTPSPVISWTVNNSP---RQGAAVDEAGRSSLII 2432 Query: 168 QDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT---GSSVTFQCR 224 ++ +DAG Y C+A N G+ + ++ +++ +P ++ G + ++QT GSS C Sbjct: 2433 ENVTTSDAGTYVCVAENRVGSVRT-LSFVRVR-EPPVLKG-DAHMSQTVIQGSSTILDCP 2489 Query: 225 VGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNV-ILADEGEYSCEAENSVGAVSA 283 + GDP P + W R G + R++ L +GSL + +V + EGEY C AEN G Sbjct: 2490 IHGDPSPVLQWLRD-GNALLRSHRIQALLNGSLVIYSVNVNTHEGEYQCLAENEAGTAER 2548 Query: 284 SGYLTV 289 + L V Sbjct: 2549 TIALKV 2554 Score = 37.9 bits (84), Expect = 1.7 Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 1/65 (1%) Query: 424 TPEPIIAWYFEG-EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482 +P P I W+ G E + +V DG LV++ S SG +TCVA++ G L Sbjct: 460 SPRPKIRWFRNGLEIHPEQSDFSVGEDGALVIRAASASHSGDFTCVATNEAGSVERKTRL 519 Query: 483 LVDSP 487 V+ P Sbjct: 520 KVNVP 524 >UniRef50_UPI0000E48C89 Cluster: PREDICTED: similar to Nr-CAM protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Nr-CAM protein - Strongylocentrotus purpuratus Length = 1235 Score = 159 bits (385), Expect = 6e-37 Identities = 133/474 (28%), Positives = 196/474 (41%), Gaps = 21/474 (4%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLR 70 P I+EQP + P TL CRA G P P+ WYK G L V + R+ L G L Sbjct: 24 PSIVEQPESINGDTRLPLTLTCRATGIPEPSYYWYKDGALFDVDNNDRASLDGGNLVIES 83 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC- 129 T +D G Y C A N GTA S+ +A + + PE+ Q QG + L C Sbjct: 84 LT----TADDGQYQCFANNRLGTAMSQKIMTSLAFMDQFENTAPETIQVDQGRPLKLRCG 139 Query: 130 -LP--PRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN- 184 P P G+P P +YW + ++R++ GNLV + +DA Y C A N Sbjct: 140 GSPGVPNGNPAPLIYWTDAAAKPTPITYNARINQDPEGNLVFSNVIASDAKGYYCQAINN 199 Query: 185 -AAGTRESAIATLKIHIK--PYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 ++ + TL + ++ LIT P + +A +C G P P + W+R Sbjct: 200 VVGSSQRTPKVTLMVSVESGASLITKPAANEIAIRTQLFKLKCIAYGYPTPVITWKRGEE 259 Query: 241 GGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299 GRV + + G L + V +D+G Y+C A N+ G S +TV P P Sbjct: 260 QLQSG-GRVSIEESGQELVISTVENSDKGTYTCVASNTGGDDEFSTVVTVESAPYFPAPP 318 Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF-PGMSRDKYHATAVFDGVTVLTI 358 + G C + G P P + W V G F + +++ + ++I Sbjct: 319 SDETKGPGESVDIECRSEGVPAPAVDWLVNGQPWADFESNIDTERWTVVTGNPQLATISI 378 Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418 ++ DS N C A N L V S R P T ++ S A F Sbjct: 379 SNLQTTDS-NVFQCIATNKYKEELTSVVLNVVSIPARIPS-FTPVTRKLSVVEDSSAAFT 436 Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTN-DGTLVLKDLDKSDSGTYTCVASS 471 C P P I W F+G L + + G++V+ + + DSG Y C A + Sbjct: 437 CHVEGRPTPTITWTFKGSVLTNGDKYTIDELAGSIVINNALEVDSGAYECTAEN 490 Score = 109 bits (262), Expect = 5e-22 Identities = 128/481 (26%), Positives = 196/481 (40%), Gaps = 57/481 (11%) Query: 18 PLDVTVARHQPATLNCRAG-----GSPSPAIRWYKGGVLVVSDTHRSIL---PAGGLFFL 69 P + V + +P L C G+P+P I W T+ + + P G L F Sbjct: 123 PETIQVDQGRPLKLRCGGSPGVPNGNPAPLIYWTDAAAKPTPITYNARINQDPEGNLVFS 182 Query: 70 RATHGRVHSDAGVYWCEATNSY--GTARSRNATLHVAVLREEFRL-EPESKQSA-QGDTV 125 + SDA Y+C+A N+ + R+ TL V+V + +P + + A + Sbjct: 183 NV----IASDAKGYYCQAINNVVGSSQRTPKVTLMVSVESGASLITKPAANEIAIRTQLF 238 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARN 184 L+C+ G P P + WK+ + L G R+ + + G LVI +D G Y C+A N Sbjct: 239 KLKCIA-YGYPTPVITWKRGEEQLQSGG--RVSIEESGQELVISTVENSDKGTYTCVASN 295 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--- 241 G E + + + PY P D G SV +CR G P P V W + Sbjct: 296 TGGDDEFS-TVVTVESAPYFPAPPSDETKGPGESVDIECRSEGVPAPAVDWLVNGQPWAD 354 Query: 242 --GNMPLGRVKVLDDG----SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-P-- 292 N+ R V+ ++ + N+ D + C A N S L V P Sbjct: 355 FESNIDTERWTVVTGNPQLATISISNLQTTDSNVFQCIATNKYKEELTSVVLNVVSIPAR 414 Query: 293 -PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 PS ++V + A FTC GRP PT+ W+ +G+ ++ G DKY + Sbjct: 415 IPSFTPVTRKLSVVEDSSAAFTCHVEGRPTPTITWTFKGS--VLTNG---DKYTIDELAG 469 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYA-GSSF-VRGKLTVTSDDDRPPPIITNGPSNQTL 409 + IN+ + DS C+A N G + G T+T IIT P++ T+ Sbjct: 470 SIV---INNALEVDS-GAYECTAENSIDGQDYEATGSATLTV---LGKTIITLPPADLTV 522 Query: 410 PIKSMAVFPCTAICTPE---PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYT 466 + A F C E P W +G+ L N ++ D + S+SGTYT Sbjct: 523 REDTTATFQCEITYDHELDKPETYWMKDGQRLEANQDNSLRIDNAMF------SNSGTYT 576 Query: 467 C 467 C Sbjct: 577 C 577 Score = 108 bits (259), Expect = 1e-21 Identities = 109/399 (27%), Positives = 165/399 (41%), Gaps = 43/399 (10%) Query: 115 ESKQSAQGDTVVLECLPPR--GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ 172 E +S GDT + L R G PEP+ YW K+G D + R L DGGNLVI+ Sbjct: 28 EQPESINGDTRLPLTLTCRATGIPEPSYYWYKDGALFDVDNNDRASL-DGGNLVIESLTT 86 Query: 173 TDAGRYQCIARNAAGTRESA-IATLKIHIKPYLITGPEDVVAQTGSSVTFQCR-----VG 226 D G+YQC A N GT S I T + + T PE + G + +C Sbjct: 87 ADDGQYQCFANNRLGTAMSQKIMTSLAFMDQFENTAPETIQVDQGRPLKLRCGGSPGVPN 146 Query: 227 GDPLPDVLWRRSAGGGNMPLGRVKVLDD--GSLRLDNVILADEGEYSCEAENSV-GAVSA 283 G+P P + W +A ++ D G+L NVI +D Y C+A N+V G+ Sbjct: 147 GNPAPLIYWTDAAAKPTPITYNARINQDPEGNLVFSNVIASDAKGYYCQAINNVVGSSQR 206 Query: 284 SGYLT----VYDPPSINLSP--NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337 + +T V S+ P N + + + + + C A G P P + W G + Sbjct: 207 TPKVTLMVSVESGASLITKPAANEIAIRT-QLFKLKCIAYGYPTPVITWK-RGEEQLQSG 264 Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397 G ++ + L I+ T +N + T C A N G +TV S P Sbjct: 265 GR-------VSIEESGQELVIS-TVENSDKGTYTCVASNTGGDDEFSTVVTVESAPYFPA 316 Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG------EALIQNHRRNVTNDG- 450 P PS++T C + P P + W G E+ I R V Sbjct: 317 P-----PSDETKGPGESVDIECRSEGVPAPAVDWLVNGQPWADFESNIDTERWTVVTGNP 371 Query: 451 ---TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486 T+ + +L +DS + C+A++++ + + S L V S Sbjct: 372 QLATISISNLQTTDSNVFQCIATNKYKEELTSVVLNVVS 410 Score = 106 bits (255), Expect = 3e-21 Identities = 78/304 (25%), Positives = 131/304 (43%), Gaps = 16/304 (5%) Query: 192 AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251 A TL + P ++ PE + T +T CR G P P W + ++ Sbjct: 14 ATLTLAYDVPPSIVEQPESINGDTRLPLTLTCRATGIPEPSYYWYKDGALFDVDNNDRAS 73 Query: 252 LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT--VYDPPSINLSPNSVNVESGNV 309 LD G+L ++++ AD+G+Y C A N +G + +T + N +P ++ V+ G Sbjct: 74 LDGGNLVIESLTTADDGQYQCFANNRLGTAMSQKIMTSLAFMDQFENTAPETIQVDQGRP 133 Query: 310 ARFTCTAT-----GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 + C + G P P ++W+ + Y+A D L ++ + Sbjct: 134 LKLRCGGSPGVPNGNPAPLIYWTDAAAKPTPIT------YNARINQDPEGNLVFSNVIAS 187 Query: 365 DSRNTIVCSAVN-YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423 D++ C A+N GSS K+T+ + +IT +N+ + C A Sbjct: 188 DAKG-YYCQAINNVVGSSQRTPKVTLMVSVESGASLITKPAANEIAIRTQLFKLKCIAYG 246 Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482 P P+I W E L R ++ G LV+ ++ SD GTYTCVAS+ G +S + Sbjct: 247 YPTPVITWKRGEEQLQSGGRVSIEESGQELVISTVENSDKGTYTCVASNTGGDDEFSTVV 306 Query: 483 LVDS 486 V+S Sbjct: 307 TVES 310 Score = 95.9 bits (228), Expect = 6e-18 Identities = 81/308 (26%), Positives = 132/308 (42%), Gaps = 28/308 (9%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-----DTHRSI 60 VT APY P D T + + CR+ G P+PA+ W G DT R Sbjct: 306 VTVESAPYFPAPPSDETKGPGESVDIECRSEGVPAPAVDWLVNGQPWADFESNIDTERWT 365 Query: 61 LPAGGLFFLRATHGRVH-SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPES-KQ 118 + G + + +D+ V+ C ATN Y + V++ P + K Sbjct: 366 VVTGNPQLATISISNLQTTDSNVFQCIATNKYKEELTSVVLNVVSIPARIPSFTPVTRKL 425 Query: 119 SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY 178 S D+ G P P + W G ++L +GD G++VI +A + D+G Y Sbjct: 426 SVVEDSSAAFTCHVEGRPTPTITWTFKG-SVLTNGDKYTIDELAGSIVINNALEVDSGAY 484 Query: 179 QCIARNAAGTRE---SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD---PLPD 232 +C A N+ ++ + ATL + K + P D+ + ++ TFQC + D P+ Sbjct: 485 ECTAENSIDGQDYEATGSATLTVLGKTIITLPPADLTVREDTTATFQCEITYDHELDKPE 544 Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSC-------EAENSVGAVSASG 285 W + R++ D SLR+DN + ++ G Y+C E+ ++V +V+AS Sbjct: 545 TYWMKDG-------QRLEANQDNSLRIDNAMFSNSGTYTCFVETTLDESTDTVHSVNASA 597 Query: 286 YLTVYDPP 293 L V P Sbjct: 598 QLVVKGHP 605 Score = 44.8 bits (101), Expect = 0.015 Identities = 31/147 (21%), Positives = 57/147 (38%), Gaps = 6/147 (4%) Query: 689 VSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTV 748 + F + + + Y +YEF + G + + P P + + ++ V Sbjct: 758 IQNFIVNARKPYEEYEFSVRSMNSGGPGPEPEIHYGFSGEAAPGASPSGVTVEAISANEV 817 Query: 749 HLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSV 808 ++ W P + + NG + GYNV N + + + ++ NL + +Y + Sbjct: 818 NVTWEPIDPEDANGKLGGYNVYYNVKIASGQDKQMCVK------SPCVVGNLQAATTYEI 871 Query: 809 QIAAETIIGLGPFSQKVYFNIDSRSVG 835 + A T G GP S V DS G Sbjct: 872 TVKAFTNAGEGPASDVVEVVTDSAPPG 898 Score = 39.9 bits (89), Expect = 0.41 Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 4/78 (5%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753 + +L+ T YE + F EG P++ V D P GP +++ + + V L W Sbjct: 860 VGNLQAATTYEITVKAFTNAGEG-PASDVVEVVTDSAPPGPVYKLKVDVYSYRLV-LNWQ 917 Query: 754 PPELQLQNGIITGYNVVV 771 P L NG +TGYNV++ Sbjct: 918 EPILT--NGDLTGYNVII 933 >UniRef50_Q12860 Cluster: Contactin-1 precursor; n=31; Euteleostomi|Rep: Contactin-1 precursor - Homo sapiens (Human) Length = 1018 Score = 159 bits (385), Expect = 6e-37 Identities = 139/497 (27%), Positives = 210/497 (42%), Gaps = 48/497 (9%) Query: 9 GEAPYIIEQPLDVTVARHQ---PATLNCRAGGSPSPAIRWY--KGGVLVVSDTHRSILPA 63 G P EQP++ +LNCRA SP P +W G V + SD + + Sbjct: 38 GFGPIFEEQPINTIYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMV--- 94 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123 GG + + DAG+Y+C A+N+YG RS ATL L E + +G Sbjct: 95 GGNLVINNPDKQ--KDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGK 152 Query: 124 TVVLECLPPRGSPEPNVY-WKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCI 181 +VL C PP P+ Y W N + D R + GNL I + +D G Y C Sbjct: 153 GMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCF 212 Query: 182 ARNAAGTR---ESAIATLKI---HIKPY---LITGPEDVVAQTGSSVTFQCRVGGDPLPD 232 + + T+ I + I KPY ++ +DV A G +VT +C G+P+PD Sbjct: 213 VSSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPD 272 Query: 233 VLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291 + WR+ MP ++ G+ L++ N+ L DEG Y CEAEN G + V Sbjct: 273 IRWRKVL--EPMP-STAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQA 329 Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 P N V+ G+ + C ATG+P PT+ W G YH Sbjct: 330 FPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGY-----------AYHKGE--- 375 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411 L + D ++ C A N G+ + +L + + P N + L Sbjct: 376 ----LRLYDV-TFENAGMYQCIAENTYGAIYANAELKILA---LAPTFEMNPMKKKILAA 427 Query: 412 K-SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470 K + C P+P +W E L+ + R + DG+L + ++ ++D G YTC A Sbjct: 428 KGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAE 487 Query: 471 SRHGKYVWSGALLVDSP 487 + GK +G L++ P Sbjct: 488 NNRGKANSTGTLVITDP 504 Score = 115 bits (276), Expect = 9e-24 Identities = 119/446 (26%), Positives = 188/446 (42%), Gaps = 36/446 (8%) Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73 I+ Q DV Q TL C A G+P P IRW K VL + I +G + L+ + Sbjct: 244 IVVQFKDVYALMGQNVTLECFALGNPVPDIRWRK--VLEPMPSTAEISTSGAV--LKIFN 299 Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133 ++ D G+Y CEA N G + + A ++V E +++ G + C+ Sbjct: 300 IQLE-DEGIYECEAENIRGKDKHQ-ARIYVQAFPEWVEHINDTEVDI-GSDLYWPCVAT- 355 Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193 G P P + W KNG + G L + D +AG YQCIA N G A Sbjct: 356 GKPIPTIRWLKNG-----------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIY-AN 403 Query: 194 ATLKI-HIKPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250 A LKI + P P + ++A G V +C+ P P W + + R+ Sbjct: 404 AELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEW-LVNSSRIL 462 Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310 + +DGSL ++N+ D G Y+C AEN+ G +++G L + DP I L+P + ++ G A Sbjct: 463 IWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENA 522 Query: 311 RFTCTATGRP--EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD-KNDSR 367 C A+ P + T WS G +I Y + D L I + K+ R Sbjct: 523 TMQCAASFDPALDLTFVWSFNG--YVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGR 580 Query: 368 NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427 T C+A +S L V R PP G + + S+A+ P Sbjct: 581 YT--CTAQTIVDNSSASADLVV-----RGPPGPPGGLRIEDIRATSVALTWSRGSDNHSP 633 Query: 428 IIAWYFEGEALIQNHRRNVTNDGTLV 453 I + + + ++ + ++ D ++ Sbjct: 634 ISKYTIQTKTILSDDWKDAKTDPPII 659 Score = 112 bits (269), Expect = 6e-23 Identities = 167/723 (23%), Positives = 274/723 (37%), Gaps = 101/723 (13%) Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181 G V LEC G+P P++ W+K + + + G L I + + D G Y+C Sbjct: 256 GQNVTLECFA-LGNPVPDIRWRKVLEPMPSTAEIS---TSGAVLKIFNIQLEDEGIYECE 311 Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241 A N G ++ A + + P + D GS + + C G P+P + W ++ Sbjct: 312 AENIRG-KDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNG-- 368 Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLSPN 300 G LRL +V + G Y C AEN+ GA+ A+ L + P+ ++P Sbjct: 369 --------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPM 420 Query: 301 SVNVESGNVAR--FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358 + + R C P+P WS +G ++ + DG L I Sbjct: 421 KKKILAAKGGRVIIECKPKAAPKPKFSWS-KGTEWLV------NSSRILIWEDGS--LEI 471 Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418 N+ +ND C A N G + G L +T P I P N + + A Sbjct: 472 NNITRNDG-GIYTCFAENNRGKANSTGTLVITD-----PTRIILAPINADITVGENATMQ 525 Query: 419 CTAICTP--EPIIAWYFEGEALIQN-----HRRN--VTNDGTLVLKDLDKSDSGTYTCVA 469 C A P + W F G + N ++RN + ++G L++++ +G YTC A Sbjct: 526 CAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTA 585 Query: 470 SSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529 + S L+V P PGPP ++ TSV L+WS+ + Sbjct: 586 QTIVDNSSASADLVVRGP----------------PGPPGGLRIEDIRATSVALTWSRGSD 629 Query: 530 IGSSSILGYQVE---VFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFI 586 S I Y ++ + S + P G + AR V LIP + Y F Sbjct: 630 -NHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAV--------DLIPWMEYEFR 680 Query: 587 VRTENSHGLSGPSPVSDSV-TVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPID 645 V N+ G PS S+ + T G N G RN LT I P+ Sbjct: 681 VVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGG---RNRELT------ITWAPLS 731 Query: 646 SKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEI---TSLRKYTK 702 + + N + G + F+P D E K + +N +G + ++ T Sbjct: 732 RE-----YHYGNNF---GYIVAFKPFDG----EEWKKVTVTNPDTGRYVHKDETMSPSTA 779 Query: 703 YEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNG 762 ++ + F K +G S V + D P P + + +L+++ + + W + Sbjct: 780 FQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWE----HVLEK 835 Query: 763 IITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFS 822 I+ Y + W ++ + T Q S + NL Y +++ A G GP S Sbjct: 836 IVESYQIRY-WAAHDKEEAANRVQVT-SQEYSARLENLLPDTQYFIEVGACNSAGCGPPS 893 Query: 823 QKV 825 + Sbjct: 894 DMI 896 Score = 39.9 bits (89), Expect = 0.41 Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 6/91 (6%) Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSM---AVFPCTAICTPEPIIAWYFE-GEALIQNHRR 444 V+ +D PI P N P +S+ C A +P P+ W G+ + + R Sbjct: 32 VSEEDKGFGPIFEEQPINTIYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRY 91 Query: 445 NVTNDGTLVLKDLDKS-DSGTYTCVASSRHG 474 ++ G LV+ + DK D+G Y C+AS+ +G Sbjct: 92 SMVG-GNLVINNPDKQKDAGIYYCLASNNYG 121 >UniRef50_UPI0000D57997 Cluster: PREDICTED: similar to CG33519-PB; n=2; Tribolium castaneum|Rep: PREDICTED: similar to CG33519-PB - Tribolium castaneum Length = 4089 Score = 157 bits (380), Expect = 2e-36 Identities = 157/619 (25%), Positives = 246/619 (39%), Gaps = 59/619 (9%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGV--LVVSDTHRSILPAGGLFFLRATHGRVH 77 DV + + L + P P ++W K GV V S+ H + P G + + Sbjct: 2353 DVKLPIGETLRLEAQVQAHPPPEVKWIKDGVPVRVSSNIHFEVHPDGKVALI--VDCAKP 2410 Query: 78 SDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136 +AG Y + +N YG A + + + EF + + +G V E + G P Sbjct: 2411 ENAGKYELQVSNKYGDAMGEASVEIEKKPTKPEFLVRLVPQTVVEGFPVKFE-VKAVGHP 2469 Query: 137 EPNVYWKKNGQTLLFDGD--SRMHLVDGGNLVIQDA--RQTDAGRYQCIARNAAGTRESA 192 P + W +NG ++ D L DG ++++ DA + D Y+ IA N AG E++ Sbjct: 2470 APKLTWSRNGAEVISDNKHVKISELPDGTSVLLLDAANQARDGLTYRAIAINEAGEAETS 2529 Query: 193 IATLKIHI--------KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 I KP + +DV A G S+ +P+P V W + G Sbjct: 2530 APLTVIPATNSESPEEKPMFLHPLKDVTADEGKSLVLSAPFTANPVPMVEWSKD-GVPLS 2588 Query: 245 PLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLS 298 P R+ V DG L + N + +D G YS + N +G S+ V+ PP + Sbjct: 2589 PSDRILVTCDGKKVGLEILNAVPSDAGRYSVKISNPLGEESSEANAAVHKVFMPPHFTQT 2648 Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358 + G A+F C +G P+P + W+ +G P DKYH D + + Sbjct: 2649 FTDLQQLPGRDAKFPCRVSGVPQPEVVWTKDG-----LPIKESDKYHIKRDGDLCCLYVL 2703 Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP----PPIITNGPSNQTLPIKSM 414 N + D A+N G L V PP + L Sbjct: 2704 NCSP--DDAAVYRARAINKEGEEVCTASLEVVDQIQAKKKIEPPTFLKRIGDTELFKGMT 2761 Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT----LVLKDLDKSDSGTYTCVAS 470 A F A PEP + WY + L ++R + D L++ DLD++D G Y+C + Sbjct: 2762 AKFTACASGYPEPEVEWYHNDQKLFPSNRIKMETDPNGLLRLIISDLDEADLGKYSCKIT 2821 Query: 471 SRHGKYVWSGALLVDS--------PINPNIHFFRAADVSSLPGPPTKP-ITHNVTDTSVT 521 + +G + L +D PI F + P P + P I +TD T Sbjct: 2822 NEYGGDICHANLNMDEGLETRAKRPITDQYTEFDKYKRTGAPVPLSDPPIISQMTDRHCT 2881 Query: 522 LSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGI 581 LSW + G + + YQ+E+ E +G+ W + + V++L P Sbjct: 2882 LSWKPSIPPGPRAPVTYQLEMC--ELPNGD--------WFTVRTGIRSCTCGVRNLEPFR 2931 Query: 582 TYMFIVRTENSHGLSGPSP 600 Y F VR EN +G+S PSP Sbjct: 2932 DYKFRVRVENKYGISDPSP 2950 Score = 115 bits (276), Expect = 9e-24 Identities = 137/523 (26%), Positives = 215/523 (41%), Gaps = 33/523 (6%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-THRSILPAGGLFF 68 E P II D V + ++ RA G P P IRW G +V D H+ A Sbjct: 2149 EKPTIITGLSDDQVEHTKEISVMVRADGLPKPQIRWLLNGKPIVEDEKHKIESHADAQVT 2208 Query: 69 LRATHGRVH-SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPE-SKQSAQGDTVV 126 T + SD+G+Y A N G A +A + + F + E S+ +G+ + Sbjct: 2209 STLTVSDFNDSDSGIYKAIAANVQGEA-DTSARITMVQTPPTFGKKLERSEDVIEGEPLE 2267 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNA 185 L+ GSP+P V W KNG+ + + L DG L I+ AR +D+G Y+ + +N Sbjct: 2268 LKA-KINGSPKPTVVWYKNGEPIDDERVKTSVLPDGTVKLNIEHARPSDSGAYKLVIQNP 2326 Query: 186 AGTRE--SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 G A+A + +P + +DV G ++ + +V P P+V W + Sbjct: 2327 NGESACLCAVAVQQKPQRPKFLKCFKDVKLPIGETLRLEAQVQAHPPPEVKWIKDGVPVR 2386 Query: 244 MPLG-RVKVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS-----I 295 + +V DG + L D + G+Y + N G + + P+ + Sbjct: 2387 VSSNIHFEVHPDGKVALIVDCAKPENAGKYELQVSNKYGDAMGEASVEIEKKPTKPEFLV 2446 Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY-HATAVFDGVT 354 L P +V VE G +F A G P P + WS G I S +K+ + + DG + Sbjct: 2447 RLVPQTV-VE-GFPVKFEVKAVGHPAPKLTWSRNGAEVI-----SDNKHVKISELPDGTS 2499 Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV----TSDDDRPPPIITNGPSNQTLP 410 VL ++ ++ T A+N AG + LTV S+ P+ + + T Sbjct: 2500 VLLLDAANQARDGLTYRAIAINEAGEAETSAPLTVIPATNSESPEEKPMFLHPLKDVTAD 2559 Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLV-LKDLD--KSDSGTYTC 467 V P P++ W +G L + R VT DG V L+ L+ SD+G Y+ Sbjct: 2560 EGKSLVLSAPFTANPVPMVEWSKDGVPLSPSDRILVTCDGKKVGLEILNAVPSDAGRYSV 2619 Query: 468 VASSRHGKYVWSGALLVDSPINPNIHFFRA-ADVSSLPGPPTK 509 S+ G+ V P HF + D+ LPG K Sbjct: 2620 KISNPLGEESSEANAAVHKVFMPP-HFTQTFTDLQQLPGRDAK 2661 Score = 98.7 bits (235), Expect = 8e-19 Identities = 99/342 (28%), Positives = 142/342 (41%), Gaps = 40/342 (11%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGLFF 68 + P + + D +A + + G P+P + ++K GV+V SD + I F Sbjct: 951 DKPEFVVKLKDTELAENTYLRFMVKVRGDPNPDVIFFKDGVIVEKSDRYEVIREHSDRGF 1010 Query: 69 LRATHGRVH-SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127 V SDAG Y C A+N +G S ATL V E K +G Sbjct: 1011 YELLIPEVQMSDAGEYKCVASNKWGED-SCEATLKVTT-------EDLHKDMPEG----- 1057 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-----LVIQDARQTDAGRYQCIA 182 E LPP +PE WKK+G F+ D R ++ G + LV Q R D G Y C+A Sbjct: 1058 EILPPGETPE--FQWKKDGAP--FEPDERFKVLMGDDEDSLALVFQHVRAEDVGLYTCVA 1113 Query: 183 RNAAGTRESAIATLKIH----------IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232 + + G S A L +H KP LI + V G S + +V G P P Sbjct: 1114 QTSRG-HISCSAELTVHGTVNQLVREPEKPVLIVEKRNPVVNAGGSAMIELQVKGFPKPQ 1172 Query: 233 VLWRRSAGGGNMPLGRVKVLDDG----SLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288 V W G G+ K L + SL + +V D G+Y C AEN +G+ +A LT Sbjct: 1173 VKWTHE-GKPIEAGGKYKFLYEDEETMSLVIKDVQKEDAGKYLCTAENEIGSDTAEMTLT 1231 Query: 289 VYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330 V PP + V+ + + G P P + + +G Sbjct: 1232 VKTPPKLRKKIEDVDAHADLLLEIPVEIEGTPRPKVVFYKDG 1273 Score = 98.3 bits (234), Expect = 1e-18 Identities = 122/468 (26%), Positives = 190/468 (40%), Gaps = 39/468 (8%) Query: 40 SPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS-DAGVYWCEATNSYG-TARSR 97 +P +W K G D +L L V + D G+Y C A S G + S Sbjct: 1065 TPEFQWKKDGAPFEPDERFKVLMGDDEDSLALVFQHVRAEDVGLYTCVAQTSRGHISCSA 1124 Query: 98 NATLHVAV---LREEFR----LEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150 T+H V +RE + +E + G + ++E L +G P+P V W G+ + Sbjct: 1125 ELTVHGTVNQLVREPEKPVLIVEKRNPVVNAGGSAMIE-LQVKGFPKPQVKWTHEGKPIE 1183 Query: 151 FDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208 G + D +LVI+D ++ DAG+Y C A N G+ ++A TL + P L Sbjct: 1184 AGGKYKFLYEDEETMSLVIKDVQKEDAGKYLCTAENEIGS-DTAEMTLTVKTPPKLRKKI 1242 Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILA 265 EDV A + + G P P V++ + G R+KV+++ L ++ +L Sbjct: 1243 EDVDAHADLLLEIPVEIEGTPRPKVVFYKD-GKEIKKDERIKVVEENEKVVLVIEKTMLK 1301 Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNVESGNVARFTCTATGRPEPT 323 D G YS A N + +S L V+ P I L + + V PE Sbjct: 1302 DSGSYSIVATNELAQISEFFNLHVHTKPKILEKLGKDKI-VSQEEKFELRVKIESEPEAE 1360 Query: 324 MFWSVEGNRTIIFPGMSRDKYHATAVFDGVT-VLTINDTDKNDSRNTIVCSAVNYAGSSF 382 + W + + H DG T +L I D+ V AVN GS Sbjct: 1361 VKWYKDDAEI-------KSSDHYVIKKDGETYILKITGAVTTDAARYKV-KAVNIHGS-- 1410 Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI-CTPEPIIAWYFEGEALIQN 441 V + V D + P IT G + T+ V + P+P + WY + + + Sbjct: 1411 VEDDIRV---DVKKAPKITKGLQDMTVNEHDKQVTLDVKVEAFPKPSVKWYLDEMEITET 1467 Query: 442 HR---RNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485 R ++DG LV+K+++ SG YTC S+ G S L V+ Sbjct: 1468 KTEFTRVDSDDGVKLVIKEVNSELSGKYTCKLSNECGSTETSAKLTVN 1515 Score = 94.7 bits (225), Expect = 1e-17 Identities = 116/485 (23%), Positives = 184/485 (37%), Gaps = 35/485 (7%) Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82 V +P L + GSP P + WYK G + + ++ + G L H R SD+G Sbjct: 2260 VIEGEPLELKAKINGSPKPTVVWYKNGEPIDDERVKTSVLPDGTVKLNIEHAR-PSDSGA 2318 Query: 83 YWCEATNSYGTARSRNA-TLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVY 141 Y N G + A + R +F + + G+T+ LE + P P V Sbjct: 2319 YKLVIQNPNGESACLCAVAVQQKPQRPKFLKCFKDVKLPIGETLRLEA-QVQAHPPPEVK 2377 Query: 142 WKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTR--ESAIATLK 197 W K+G + + + G L++ A+ +AG+Y+ N G E+++ K Sbjct: 2378 WIKDGVPVRVSSNIHFEVHPDGKVALIVDCAKPENAGKYELQVSNKYGDAMGEASVEIEK 2437 Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDG 255 KP + G V F+ + G P P + W R+ VK+ L DG Sbjct: 2438 KPTKPEFLVRLVPQTVVEGFPVKFEVKAVGHPAPKLTWSRNGAEVISDNKHVKISELPDG 2497 Query: 256 S--LRLDNVILADEG-EYSCEAENSVGAVSASGYLTVYDPPSINLSP----------NSV 302 + L LD A +G Y A N G S LTV P + + SP V Sbjct: 2498 TSVLLLDAANQARDGLTYRAIAINEAGEAETSAPLTVI-PATNSESPEEKPMFLHPLKDV 2556 Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362 + G + T P P + WS +G P D+ T V + +N Sbjct: 2557 TADEGKSLVLSAPFTANPVPMVEWSKDG-----VPLSPSDRILVTCDGKKVGLEILNAVP 2611 Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422 + R ++ S N G V PP Q LP + A FPC Sbjct: 2612 SDAGRYSVKIS--NPLGEESSEANAAV-HKVFMPPHFTQTFTDLQQLPGRD-AKFPCRVS 2667 Query: 423 CTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGKYVWS 479 P+P + W +G + ++ + ++ DG L + + D+ Y A ++ G+ V + Sbjct: 2668 GVPQPEVVWTKDGLPIKESDKYHIKRDGDLCCLYVLNCSPDDAAVYRARAINKEGEEVCT 2727 Query: 480 GALLV 484 +L V Sbjct: 2728 ASLEV 2732 Score = 88.6 bits (210), Expect = 9e-16 Identities = 73/288 (25%), Positives = 130/288 (45%), Gaps = 14/288 (4%) Query: 12 PYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 P I+E+ D V++ + L + P ++WYK + S H I G + L+ Sbjct: 1329 PKILEKLGKDKIVSQEEKFELRVKIESEPEAEVKWYKDDAEIKSSDHYVIKKDGETYILK 1388 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130 T G V +DA Y +A N +G+ + + V + + + + V L+ + Sbjct: 1389 IT-GAVTTDAARYKVKAVNIHGSVED-DIRVDVKKAPKITKGLQDMTVNEHDKQVTLD-V 1445 Query: 131 PPRGSPEPNVYWKKNGQTLLFDGD--SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188 P+P+V W + + +R+ DG LVI++ +G+Y C N G+ Sbjct: 1446 KVEAFPKPSVKWYLDEMEITETKTEFTRVDSDDGVKLVIKEVNSELSGKYTCKLSNECGS 1505 Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248 E++ A L ++ P +I +D + G+++ + V G P P V W R+ G R Sbjct: 1506 TETS-AKLTVNCAPRIIKQLKDTTVEEGATLHLEVEVEGCPTPTVKWLRN-GREVSADAR 1563 Query: 249 VKVLDDG------SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290 +K+ D +L ++ + +EGEY NS+G VS+ Y+TV+ Sbjct: 1564 IKISRDTQRHETFNLAVNLIKYEEEGEYEVVVTNSMGTVSSKSYVTVH 1611 Score = 88.6 bits (210), Expect = 9e-16 Identities = 102/426 (23%), Positives = 177/426 (41%), Gaps = 47/426 (11%) Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIARNAAG-TRE 190 +P P W NGQ L DSR+ + + G L I + DAG+ +CI +N G R+ Sbjct: 1878 NPPPKATWTINGQEL--KPDSRVRMTNKGEEFKLEIVKLKMDDAGKIECILKNPLGEARQ 1935 Query: 191 SAIATL---KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM--- 244 +A+ + K +P L G +D Q +++TF+ V GDP+PD W S G + Sbjct: 1936 TAMLEVTPEKELRRPKLKEGLKDQTIQKKNTLTFKAVVIGDPVPDATW--SVDGHELTSE 1993 Query: 245 PLGRVKV--------LDDG------SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290 + K+ + DG +L + + G+Y+ A+N G ++S LTV Sbjct: 1994 AFEKYKIILETEDHEIQDGLKECTYTLTIPRCERCNAGKYTFFAKNKWGECNSSAQLTVV 2053 Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350 P I P +V+V G C P+ + W+ + + K + Sbjct: 2054 LRPEIE-GPQNVSVIPGEATELVCKIQANPQAEVHWTKDDQ---VVKETENLKIVSDVAN 2109 Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410 + ++ ++ +V A N G S +L ++ P IIT +Q Sbjct: 2110 ETYRLVFKKALLSDEGYYKVV--AKNSLGESSSEARLKAVTE---KPTIITGLSDDQVEH 2164 Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN------DGTLVLKDLDKSDSGT 464 K ++V A P+P I W G+ ++++ + + + TL + D + SDSG Sbjct: 2165 TKEISVM-VRADGLPKPQIRWLLNGKPIVEDEKHKIESHADAQVTSTLTVSDFNDSDSGI 2223 Query: 465 YTCVASSRHGKYVWSGAL-LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLS 523 Y +A++ G+ S + +V +P R+ DV + G P + T+ Sbjct: 2224 YKAIAANVQGEADTSARITMVQTPPTFGKKLERSEDV--IEGEPLELKAKINGSPKPTVV 2281 Query: 524 WSQNNK 529 W +N + Sbjct: 2282 WYKNGE 2287 Score = 87.4 bits (207), Expect = 2e-15 Identities = 107/404 (26%), Positives = 152/404 (37%), Gaps = 36/404 (8%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR---SILPAGGLFF 68 P + + + TV P +A G P+P + W + G V+SD S LP G Sbjct: 2442 PEFLVRLVPQTVVEGFPVKFEVKAVGHPAPKLTWSRNGAEVISDNKHVKISELPDGTSVL 2501 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE------FRLEPESKQSA-Q 121 L + D Y A N G A + + E L P +A + Sbjct: 2502 LLDAANQAR-DGLTYRAIAINEAGEAETSAPLTVIPATNSESPEEKPMFLHPLKDVTADE 2560 Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQ 179 G ++VL P +P P V W K+G L D + DG L I +A +DAGRY Sbjct: 2561 GKSLVLSA-PFTANPVPMVEWSKDGVPLS-PSDRILVTCDGKKVGLEILNAVPSDAGRYS 2618 Query: 180 CIARNAAG--TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 N G + E+ A K+ + P+ D+ G F CRV G P P+V+W + Sbjct: 2619 VKISNPLGEESSEANAAVHKVFMPPHFTQTFTDLQQLPGRDAKFPCRVSGVPQPEVVWTK 2678 Query: 238 SAGGGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--- 291 G + + DG L + N D Y A N G + L V D Sbjct: 2679 D-GLPIKESDKYHIKRDGDLCCLYVLNCSPDDAAVYRARAINKEGEEVCTASLEVVDQIQ 2737 Query: 292 ------PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345 PP+ + G A+FT A+G PEP + W N +FP +R K Sbjct: 2738 AKKKIEPPTFLKRIGDTELFKGMTAKFTACASGYPEPEVEW--YHNDQKLFPS-NRIKME 2794 Query: 346 ATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389 +G+ L I+D D+ D C N G L + Sbjct: 2795 TDP--NGLLRLIISDLDEAD-LGKYSCKITNEYGGDICHANLNM 2835 Score = 81.0 bits (191), Expect = 2e-13 Identities = 107/466 (22%), Positives = 177/466 (37%), Gaps = 33/466 (7%) Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138 +AG Y A N +G S +A L V VLR E P++ G+ L C + +P+ Sbjct: 2029 NAGKYTFFAKNKWGECNS-SAQLTV-VLRPEIE-GPQNVSVIPGEATELVC-KIQANPQA 2084 Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGN----LVIQDARQTDAGRYQCIARNAAGTRESAIA 194 V+W K+ Q + + ++ + D N LV + A +D G Y+ +A+N+ G S Sbjct: 2085 EVHWTKDDQVVK-ETENLKIVSDVANETYRLVFKKALLSDEGYYKVVAKNSLGESSSEAR 2143 Query: 195 TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254 + KP +ITG D + ++ R G P P + W + G + + K+ Sbjct: 2144 LKAVTEKPTIITGLSDDQVEHTKEISVMVRADGLPKPQIRWLLN-GKPIVEDEKHKIESH 2202 Query: 255 GSLRLDNVIL------ADEGEYSCEAENSVGAVSASGYLT-VYDPPSINLS-PNSVNVES 306 ++ + + +D G Y A N G S +T V PP+ S +V Sbjct: 2203 ADAQVTSTLTVSDFNDSDSGIYKAIAANVQGEADTSARITMVQTPPTFGKKLERSEDVIE 2262 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 G G P+PT+ W G + ++ + + DG L I +DS Sbjct: 2263 GEPLELKAKINGSPKPTVVWYKNGE------PIDDERVKTSVLPDGTVKLNIEHARPSDS 2316 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426 N G S + V RP + LPI P Sbjct: 2317 -GAYKLVIQNPNGESACLCAVAVQQKPQRPK--FLKCFKDVKLPIGETLRLEAQVQAHPP 2373 Query: 427 PIIAWYFEG--EALIQNHRRNVTNDG--TLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482 P + W +G + N V DG L++ ++G Y S+++G + ++ Sbjct: 2374 PEVKWIKDGVPVRVSSNIHFEVHPDGKVALIVDCAKPENAGKYELQVSNKYGDAMGEASV 2433 Query: 483 LVD-SPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527 ++ P P R + + G P K V + L+WS+N Sbjct: 2434 EIEKKPTKPEF-LVRLVPQTVVEGFPVKFEVKAVGHPAPKLTWSRN 2478 Score = 68.9 bits (161), Expect = 8e-10 Identities = 76/300 (25%), Positives = 110/300 (36%), Gaps = 11/300 (3%) Query: 37 GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96 G+P P + +YK G + D ++ L + D+G Y ATN S Sbjct: 1261 GTPRPKVVFYKDGKEIKKDERIKVVEENEKVVL-VIEKTMLKDSGSYSIVATNELAQI-S 1318 Query: 97 RNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSR 156 LHV + + K +Q + L + PE V W K+ + D Sbjct: 1319 EFFNLHVHTKPKILEKLGKDKIVSQEEKFELR-VKIESEPEAEVKWYKDDAEIK-SSDHY 1376 Query: 157 MHLVDGGNLVIQ--DARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDV-VA 213 + DG +++ A TDA RY+ A N G+ E I + + P + G +D+ V Sbjct: 1377 VIKKDGETYILKITGAVTTDAARYKVKAVNIHGSVEDDIR-VDVKKAPKITKGLQDMTVN 1435 Query: 214 QTGSSVTFQCRVGGDPLPDVLW---RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEY 270 + VT +V P P V W RV D L + V G+Y Sbjct: 1436 EHDKQVTLDVKVEAFPKPSVKWYLDEMEITETKTEFTRVDSDDGVKLVIKEVNSELSGKY 1495 Query: 271 SCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330 +C+ N G+ S LTV P I VE G G P PT+ W G Sbjct: 1496 TCKLSNECGSTETSAKLTVNCAPRIIKQLKDTTVEEGATLHLEVEVEGCPTPTVKWLRNG 1555 Score = 64.1 bits (149), Expect = 2e-08 Identities = 92/453 (20%), Positives = 161/453 (35%), Gaps = 28/453 (6%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 V E P +I + + V A + + G P P ++W G + + L Sbjct: 1136 VREPEKPVLIVEKRNPVVNAGGSAMIELQVKGFPKPQVKWTHEGKPIEAGGKYKFLYEDE 1195 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 DAG Y C A N G S A + + V + A D + Sbjct: 1196 ETMSLVIKDVQKEDAGKYLCTAENEIG---SDTAEMTLTVKTPPKLRKKIEDVDAHADLL 1252 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIA 182 + + G+P P V + K+G+ + D R+ +V+ LVI+ D+G Y +A Sbjct: 1253 LEIPVEIEGTPRPKVVFYKDGKEI--KKDERIKVVEENEKVVLVIEKTMLKDSGSYSIVA 1310 Query: 183 RNAAGTRESAIATLKIHIKPYLI--TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 N + S L +H KP ++ G + +V+Q + ++ +P +V W + Sbjct: 1311 TNEL-AQISEFFNLHVHTKPKILEKLGKDKIVSQE-EKFELRVKIESEPEAEVKWYKD-D 1367 Query: 241 GGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297 + DG L++ + D Y +A N G+V + V P I Sbjct: 1368 AEIKSSDHYVIKKDGETYILKITGAVTTDAARYKVKAVNIHGSVEDDIRVDVKKAPKITK 1427 Query: 298 SPNSVNV-ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356 + V E P+P++ W ++ ++ ++ DGV L Sbjct: 1428 GLQDMTVNEHDKQVTLDVKVEAFPKPSVKWYLDEMEIT----ETKTEFTRVDSDDGVK-L 1482 Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416 I + + ++ C N GS+ KLTV P I + T+ + Sbjct: 1483 VIKEVN-SELSGKYTCKLSNECGSTETSAKLTVNC-----APRIIKQLKDTTVEEGATLH 1536 Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVTND 449 P P + W G + + R ++ D Sbjct: 1537 LEVEVEGCPTPTVKWLRNGREVSADARIKISRD 1569 Score = 60.5 bits (140), Expect = 3e-07 Identities = 50/165 (30%), Positives = 71/165 (43%), Gaps = 14/165 (8%) Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRES 191 G P+P V + N + + G M G L I + D G Y+ +A N G Sbjct: 3028 GYPKPKVSFYFNDELIESGGRFDMSYTRNGQATLFINKMLERDVGWYEAVATNEHGEARQ 3087 Query: 192 AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---R 248 + L+I P I PE A V F R+ G P P++ W + PL R Sbjct: 3088 RVR-LEIAEMPQFIRRPEIQYAMHRGKVRFDARIVGVPYPEIKWYKDW----KPLAASTR 3142 Query: 249 VKVL----DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 +KV D L ++++I DEG YS A N G++S+S L V Sbjct: 3143 IKVSSFFPDTAVLVINDIITKDEGLYSVSARNVAGSISSSAMLHV 3187 Score = 44.4 bits (100), Expect = 0.019 Identities = 51/198 (25%), Positives = 76/198 (38%), Gaps = 7/198 (3%) Query: 10 EAPYIIEQPLDVTVA-RHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68 +AP + Q D + Q L G P P + +Y L+ S + Sbjct: 3000 QAPRFLRQEHDTQYGVKDQNTNLFWFVYGYPKPKVSFYFNDELIESGGRFDMSYTRNGQA 3059 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128 + + D G Y ATN +G AR R L +A + +F PE + + V + Sbjct: 3060 TLFINKMLERDVGWYEAVATNEHGEARQR-VRLEIAEM-PQFIRRPEIQYAMHRGKVRFD 3117 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRM--HLVDGGNLVIQDARQTDAGRYQCIARNAA 186 G P P + W K+ + L ++ D LVI D D G Y ARN A Sbjct: 3118 ARIV-GVPYPEIKWYKDWKPLAASTRIKVSSFFPDTAVLVINDIITKDEGLYSVSARNVA 3176 Query: 187 GT-RESAIATLKIHIKPY 203 G+ SA+ ++ H Y Sbjct: 3177 GSISSSAMLHVEEHDHDY 3194 Score = 41.1 bits (92), Expect = 0.18 Identities = 32/118 (27%), Positives = 48/118 (40%), Gaps = 3/118 (2%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL--PAGGLFF 68 AP II+Q D TV L G P+P ++W + G V +D I F Sbjct: 1517 APRIIKQLKDTTVEEGATLHLEVEVEGCPTPTVKWLRNGREVSADARIKISRDTQRHETF 1576 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRN-ATLHVAVLREEFRLEPESKQSAQGDTV 125 A + + + G Y TNS GT S++ T+H + +E E + + V Sbjct: 1577 NLAVNLIKYEEEGEYEVVVTNSMGTVSSKSYVTVHKVTHTDAIEVEEEPPMQLKVEVV 1634 Score = 40.3 bits (90), Expect = 0.31 Identities = 25/95 (26%), Positives = 41/95 (43%), Gaps = 10/95 (10%) Query: 502 SLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV 561 S P P P + +DT + L+W Q G+S +L Y +E + + W Sbjct: 3627 STPEEPDSPESDQSSDTEIFLTWKQPRFDGNSPVLCYSLEYKLADDIE----------WT 3676 Query: 562 VIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596 A + Y+++ L P +YMF + N+ G S Sbjct: 3677 KKADNIDHEFYLMRGLTPSSSYMFRLAARNAIGWS 3711 >UniRef50_Q2VWP7 Cluster: Protogenin homolog; n=32; Euteleostomi|Rep: Protogenin homolog - Homo sapiens (Human) Length = 1150 Score = 157 bits (380), Expect = 2e-36 Identities = 136/475 (28%), Positives = 209/475 (44%), Gaps = 41/475 (8%) Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74 +++P DVTV R P L+C+A G + W K G + + +L G L ++ G Sbjct: 42 VKEPQDVTVTRKDPVVLDCQAHGEVPIKVTWLKNGAKMSENKRIEVLSNGSL-YISEVEG 100 Query: 75 R--VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP 132 R SD G Y C A N YG S+ A L ++ + F ++P S + +G C Sbjct: 101 RRGEQSDEGFYQCLAMNKYGAILSQKAHLALSTI-SAFEVQPISTEVHEGGVARFAC-KI 158 Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192 P + W+ N TL D R+ + G L I D Q D+G Y+CIA A R+S Sbjct: 159 SSHPPAVITWEFNRTTLPMTMD-RITALPTGVLQIYDVSQRDSGNYRCIAATVAHRRKSM 217 Query: 193 IATL--------KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 A+L K P +I GP+++ +V +C G+P P + W R ++ Sbjct: 218 EASLTVIPAKESKSFHTPTIIAGPQNITTSLHQTVVLECMATGNPKPIISWSR-LDHKSI 276 Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEA--ENSVGAVSASGYLTVYDPPSINLSPNSV 302 + +VL +G+L + +V L G Y C A + A LTV PPS P S+ Sbjct: 277 DVFNTRVLGNGNLMISDVRLQHAGVYVCRATTPGTRNFTVAMATLTVLAPPSFVEWPESL 336 Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362 ARF C A G P P M W ++ R I G + Y++ L IN Sbjct: 337 TRPRAGTARFVCQAEGIPSPKMSW-LKNGRKIHSNGRIK-MYNSK--------LVINQII 386 Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN---QTLPIKSMAVFPC 419 D C A N GS R +LTV +DRP + P N +T+ ++ + Sbjct: 387 PEDDA-IYQCMAENSQGSILSRARLTVVMSEDRP-----SAPYNVHAETMSSSAILLAWE 440 Query: 420 TAICTPEPIIAW---YFEGEAL-IQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVA 469 + + +IA+ Y + E L + ++ + ND T ++ DL+ + + T+ VA Sbjct: 441 RPLYNSDKVIAYSVHYMKAEGLNNEEYQVVIGNDTTHYIIDDLEPASNYTFYIVA 495 Score = 117 bits (281), Expect = 2e-24 Identities = 125/511 (24%), Positives = 191/511 (37%), Gaps = 56/511 (10%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169 F EP+ + D VVL+C G V W KNG + + R+ ++ G+L I + Sbjct: 41 FVKEPQDVTVTRKDPVVLDC-QAHGEVPIKVTWLKNGAKM--SENKRIEVLSNGSLYISE 97 Query: 170 AR-----QTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR 224 Q+D G YQC+A N G S A L + P G F C+ Sbjct: 98 VEGRRGEQSDEGFYQCLAMNKYGAILSQKAHLALSTISAFEVQPISTEVHEGGVARFACK 157 Query: 225 VGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAEN-SVGAVSA 283 + P + W + M + R+ L G L++ +V D G Y C A + S Sbjct: 158 ISSHPPAVITWEFNRTTLPMTMDRITALPTGVLQIYDVSQRDSGNYRCIAATVAHRRKSM 217 Query: 284 SGYLTV--------YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII 335 LTV + P+I P ++ C ATG P+P + WS +++I Sbjct: 218 EASLTVIPAKESKSFHTPTIIAGPQNITTSLHQTVVLECMATGNPKPIISWSRLDHKSI- 276 Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395 D ++ + +G L I+D + VC A +F T+T Sbjct: 277 ------DVFNTRVLGNG--NLMISDV-RLQHAGVYVCRATTPGTRNFTVAMATLTV---L 324 Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLK 455 PP P + T P A F C A P P ++W G + N R + N LV+ Sbjct: 325 APPSFVEWPESLTRPRAGTARFVCQAEGIPSPKMSWLKNGRKIHSNGRIKMYN-SKLVIN 383 Query: 456 DLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNV 515 + D Y C+A + G + L V P P + Sbjct: 384 QIIPEDDAIYQCMAENSQGSILSRARLTV-------------VMSEDRPSAPYNVHAETM 430 Query: 516 TDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVK 575 + +++ L+W + S ++ Y V E L+ N VVI THY++ Sbjct: 431 SSSAILLAW-ERPLYNSDKVIAYSVHYMKAEGLN------NEEYQVVIGN--DTTHYIID 481 Query: 576 SLIPGITYMFIVRTENSHGLSGPSPVSDSVT 606 L P Y F + ++ G S +SD VT Sbjct: 482 DLEPASNYTFYI---VAYMPMGASQMSDHVT 509 Score = 77.4 bits (182), Expect = 2e-12 Identities = 67/214 (31%), Positives = 93/214 (43%), Gaps = 15/214 (7%) Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67 S P II P ++T + HQ L C A G+P P I W + + + +L G L Sbjct: 231 SFHTPTIIAGPQNITTSLHQTVVLECMATGNPKPIISWSRLDHKSIDVFNTRVLGNGNLM 290 Query: 68 F--LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDT 124 +R H AGVY C AT GT A + VL +E PES + T Sbjct: 291 ISDVRLQH------AGVYVCRATTP-GTRNFTVAMATLTVLAPPSFVEWPESLTRPRAGT 343 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 C G P P + W KNG+ + +G +M+ LVI D YQC+A N Sbjct: 344 ARFVC-QAEGIPSPKMSWLKNGRKIHSNGRIKMY---NSKLVINQIIPEDDAIYQCMAEN 399 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSS 218 + G+ S A L + + + P +V A+T SS Sbjct: 400 SQGSILSR-ARLTVVMSEDRPSAPYNVHAETMSS 432 Score = 53.2 bits (122), Expect = 4e-05 Identities = 37/136 (27%), Positives = 63/136 (46%), Gaps = 11/136 (8%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753 + L TKYEF + + S TL + P GPP+ +++ ++ T + W Sbjct: 782 VQGLEPNTKYEFAVRLHVDQLSSPWSPVVYHSTLPEAPAGPPVGVKVTLIEDDTALVSWK 841 Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTV-HQ---ATSLIMTNLTSGVSYSVQ 809 PP+ ++T Y ++ + K+ +A V H+ T ++ NL +G Y V+ Sbjct: 842 PPD--GPETVVTRYTIL-----YASRKAWIAGEWQVLHREGAITMALLENLVAGNVYIVK 894 Query: 810 IAAETIIGLGPFSQKV 825 I+A +G GPFS V Sbjct: 895 ISASNEVGEGPFSNSV 910 Score = 51.2 bits (117), Expect = 2e-04 Identities = 42/186 (22%), Positives = 81/186 (43%), Gaps = 9/186 (4%) Query: 639 IEATPIDSKTIKLMWE--ILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITS 696 + A + S I L WE + N + +++ + + E E + ++ ND + + I Sbjct: 425 VHAETMSSSAILLAWERPLYNSDKVIAYSVHYMKAEGLNNE-EYQVVI-GNDTTHYIIDD 482 Query: 697 LRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPE 756 L + Y F+++ + + S+ TL+DVP PP I + + T + + W P Sbjct: 483 LEPASNYTFYIVAYMPMGASQMSDHVTQNTLEDVPLRPP-EISLTSRSPTDILISWLPIP 541 Query: 757 LQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETII 816 + + G + Y + L + ++ + T H+ ++ L Y V+I A T + Sbjct: 542 AKYRRGQVVLYRLSFR-LSTENSIQVLELPGTTHE---YLLEGLKPDSVYLVRITAATRV 597 Query: 817 GLGPFS 822 GLG S Sbjct: 598 GLGESS 603 >UniRef50_Q6WRI0 Cluster: Immunoglobulin superfamily member 10 precursor; n=20; Mammalia|Rep: Immunoglobulin superfamily member 10 precursor - Homo sapiens (Human) Length = 2623 Score = 156 bits (378), Expect = 4e-36 Identities = 144/502 (28%), Positives = 222/502 (44%), Gaps = 56/502 (11%) Query: 12 PYIIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTH----RSILPAGGL 66 P I+EQ V V + L C A G+P P++ W V + L + G Sbjct: 1842 PVILEQRRQVIVGTWGESLKLPCTAKGTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSNGT 1901 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GD 123 ++R SD G Y C AT+S G+ R R L + R+E S++ + GD Sbjct: 1902 LYIR---NLASSDRGTYECIATSSTGSER-RVVMLTMEERVTSPRIEAASQKRTEVNFGD 1957 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGD---SRMHLVDGGNLVIQDARQTDAGRYQC 180 ++L C G P+P + W+ + ++ S +H+ G+L I + D+G Y C Sbjct: 1958 KLLLNC-SATGEPKPQIMWRLPSKAVVDQQHRVGSWIHVYPNGSLFIGSVTEKDSGVYLC 2016 Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQ--CRVGGDPLPDVLWR-- 236 +ARN G + + + + +KP I + Q FQ C+ G P+P++ W Sbjct: 2017 VARNKMGD-DLILMHVSLRLKPAKIDHKQYFRKQVLHGKDFQVDCKASGSPVPEISWSLP 2075 Query: 237 --------RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288 A R + ++G+L + V +A+EG+Y+C A+N++G +LT Sbjct: 2076 DGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKDEMKVHLT 2135 Query: 289 VYDP-PSINLSPNSVN--VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345 V P I S N N +++G+ A C TG P+P +FW + N I F + R +H Sbjct: 2136 VITAAPRIRQS-NKTNKRIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISF-SIDRYTFH 2193 Query: 346 ATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPS 405 A LTIN DS VC A N +G KL V S PP+I + Sbjct: 2194 ANGS------LTINKVKLLDS-GEYVCVARNPSGDDTKMYKLDVVSK----PPLINGLYT 2242 Query: 406 NQTLPIKSMAV------FPCTAICTPEPIIAWYFEGEALIQ----NHRRNVTNDGTLVLK 455 N+T+ IK+ AV F C A TP P + W + R V +GTL ++ Sbjct: 2243 NRTV-IKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIR 2301 Query: 456 DLDKSDSGTYTCVASSRHGKYV 477 ++ SDS + CVA + G+ V Sbjct: 2302 NVRLSDSADFICVARNEGGESV 2323 Score = 126 bits (304), Expect = 4e-27 Identities = 102/375 (27%), Positives = 165/375 (44%), Gaps = 17/375 (4%) Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77 + T RH +CRA G+PSP + W + + + + S + L + R+ Sbjct: 2247 IKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRL- 2305 Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQ-GDTVVLECLPPRGS 135 SD+ + C A N G + + +LR FR K AQ G + L C G+ Sbjct: 2306 SDSADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGKSTALNC-SVDGN 2364 Query: 136 PEPNVYW-KKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193 P P + W NG S +L+ G+ +I + DAG+Y+C ARN G E + Sbjct: 2365 PPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEK-L 2423 Query: 194 ATLKIHIKPYLIT-GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG-GGNMPL--GRV 249 L+I KP ++T P V +G S++ C G P P++ W +G + P G+ Sbjct: 2424 VILEIGQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKY 2483 Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVG--AVSASGYLTVYDPPSINLSPNSVNVESG 307 + D+G+L + D G Y C+A+NSVG ++ + Y P N P S+ +G Sbjct: 2484 ILHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPRITNRPPRSIVTRTG 2543 Query: 308 NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367 + C A G P+P + W + + + S+++ H + L I + +DS Sbjct: 2544 AAFQLHCVALGVPKPEITWEMPDHS--LLSTASKERTHGSEQLHLQGTLVIQNPQTSDS- 2600 Query: 368 NTIVCSAVNYAGSSF 382 C+A N GS + Sbjct: 2601 GIYKCTAKNPLGSDY 2615 Score = 125 bits (301), Expect = 8e-27 Identities = 141/501 (28%), Positives = 201/501 (40%), Gaps = 54/501 (10%) Query: 10 EAPYIIE-QPLDVTVARHQPATLNCRAGGSPSPAIRWYK--GGVLVVSDTHRS---ILPA 63 E P I+ + T+ + A L C A G+P P I W + G+ + S +LP Sbjct: 1646 EKPRIVGGKAASFTIPANSDAFLPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPN 1705 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA--Q 121 G L R D G Y C A+N +GT + TL V LE +K+ Sbjct: 1706 GTLSIQRVE----IQDRGQYLCSASNLFGTDH-LHVTLSVVSYPPRI-LERRTKEITVHS 1759 Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGD--SRMHLVD-GGNLVIQDARQTDAGRY 178 G TV L+C G P P V W QT++ + SR +V G LV+ + D G Y Sbjct: 1760 GSTVELKC-RAEGRPSPTVTWILANQTVVSESSQGSRQAVVTVDGTLVLHNLSIYDRGFY 1818 Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRR 237 +C+A N G + I P ++ V+ T G S+ C G P P V W Sbjct: 1819 KCVASNPGGQDSLLVKIQVIAAPPVILEQRRQVIVGTWGESLKLPCTAKGTPQPSVYWVL 1878 Query: 238 SAGGGNMPL----GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-- 291 S G PL ++ + +G+L + N+ +D G Y C A +S G+ LT+ + Sbjct: 1879 SDGTEVKPLQFTNSKLFLFSNGTLYIRNLASSDRGTYECIATSSTGSERRVVMLTMEERV 1938 Query: 292 -PPSIN-LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349 P I S V G+ C+ATG P+P + W + + D+ H Sbjct: 1939 TSPRIEAASQKRTEVNFGDKLLLNCSATGEPKPQIMWRLPSKAVV-------DQQHRVGS 1991 Query: 350 FDGV---TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP-S 405 + V L I + DS +C A N G + L S +P I Sbjct: 1992 WIHVYPNGSLFIGSVTEKDS-GVYLCVARNKMGDDLI---LMHVSLRLKPAKIDHKQYFR 2047 Query: 406 NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN--------HR-RNVT--NDGTLVL 454 Q L K V C A +P P I+W +I N HR R T N+GTL Sbjct: 2048 KQVLHGKDFQV-DCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYF 2106 Query: 455 KDLDKSDSGTYTCVASSRHGK 475 + ++ G YTC A + GK Sbjct: 2107 NKVGVAEEGDYTCYAQNTLGK 2127 Score = 125 bits (301), Expect = 8e-27 Identities = 124/489 (25%), Positives = 205/489 (41%), Gaps = 39/489 (7%) Query: 12 PYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD----THRSILPAGGL 66 P I+E+ ++TV L CRA G PSP + W VVS+ + ++++ G Sbjct: 1745 PRILERRTKEITVHSGSTVELKCRAEGRPSPTVTWILANQTVVSESSQGSRQAVVTVDGT 1804 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ---SAQGD 123 L H D G Y C A+N G + + + V+ + + +Q G+ Sbjct: 1805 LVL---HNLSIYDRGFYKCVASNPGG---QDSLLVKIQVIAAPPVILEQRRQVIVGTWGE 1858 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQT----LLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179 ++ L C +G+P+P+VYW + T L F +S++ L G L I++ +D G Y+ Sbjct: 1859 SLKLPC-TAKGTPQPSVYWVLSDGTEVKPLQFT-NSKLFLFSNGTLYIRNLASSDRGTYE 1916 Query: 180 CIARNAAGT-RESAIATLKIHIKPYLITGPEDVVAQT--GSSVTFQCRVGGDPLPDVLWR 236 CIA ++ G+ R + T++ + I + G + C G+P P ++WR Sbjct: 1917 CIATSSTGSERRVVMLTMEERVTSPRIEAASQKRTEVNFGDKLLLNCSATGEPKPQIMWR 1976 Query: 237 ---RSAGGGNMPLGR-VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV-YD 291 ++ +G + V +GSL + +V D G Y C A N +G ++++ Sbjct: 1977 LPSKAVVDQQHRVGSWIHVYPNGSLFIGSVTEKDSGVYLCVARNKMGDDLILMHVSLRLK 2036 Query: 292 PPSINLSPN-SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT--- 347 P I+ V G + C A+G P P + WS+ I + D H T Sbjct: 2037 PAKIDHKQYFRKQVLHGKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRY 2096 Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407 +F+ T L N + C A N G ++ LTV + P I + +N+ Sbjct: 2097 TLFNNGT-LYFNKVGVAE-EGDYTCYAQNTLGKDEMKVHLTVIT---AAPRIRQSNKTNK 2151 Query: 408 TLPIKSMAVFPCTAICTPEPIIAWYFEGEALI--QNHRRNVTNDGTLVLKDLDKSDSGTY 465 + AV C P+P I W +I R +G+L + + DSG Y Sbjct: 2152 RIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVKLLDSGEY 2211 Query: 466 TCVASSRHG 474 CVA + G Sbjct: 2212 VCVARNPSG 2220 Score = 120 bits (288), Expect = 3e-25 Identities = 120/469 (25%), Positives = 189/469 (40%), Gaps = 38/469 (8%) Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVS-DTHRSILPAGGLFFLRATHGRVHSDAGVYWCEA 87 A L+C G P P I W ++S R A G + D+G Y C A Sbjct: 2159 AVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVK---LLDSGEYVCVA 2215 Query: 88 TNSYGTARSR---NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK 144 N G + ++ + K +A + G+P P V W Sbjct: 2216 RNPSGDDTKMYKLDVVSKPPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIM 2275 Query: 145 NGQTLLFDG--DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA--TLKIHI 200 L SR+ + G L I++ R +D+ + C+ARN G + L++ Sbjct: 2276 PDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLR 2335 Query: 201 KPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPLG-RVKVLDDG 255 +P P E +VAQ G S C V G+P P+++W G N P + + +G Sbjct: 2336 RP-TFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNG 2394 Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-NLSPNSVNVESGNVARFTC 314 S + D G+Y C A N VG + L + P I +P +V SG C Sbjct: 2395 SFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQKPVILTYAPGTVKGISGESLSLHC 2454 Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374 + G P+P + W++ + P ++ KY + D T L I + D R +C A Sbjct: 2455 VSDGIPKPNIKWTMPSGYVVDRPQIN-GKY---ILHDNGT-LVIKEATAYD-RGNYICKA 2508 Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP--CTAICTPEPIIAWY 432 N G + + + + + PP ITN P +++ ++ A F C A+ P+P I W Sbjct: 2509 QNSVGHTLITVPVMIVAY----PPRITNRPP-RSIVTRTGAAFQLHCVALGVPKPEITWE 2563 Query: 433 FEGEALIQNHRRNVTN-------DGTLVLKDLDKSDSGTYTCVASSRHG 474 +L+ + T+ GTLV+++ SDSG Y C A + G Sbjct: 2564 MPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLG 2612 Score = 117 bits (281), Expect = 2e-24 Identities = 123/476 (25%), Positives = 204/476 (42%), Gaps = 52/476 (10%) Query: 31 LNCRAGGSPSPAIRW-YKGGVLV-----VSDT-HRS----ILPAGGLFFLRATHGRVHSD 79 ++C+A GSP P I W G ++ D+ HR+ + G L+F + ++ Sbjct: 2058 VDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVGV----AE 2113 Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GDTVVLECLPPRGSP 136 G Y C A N+ G + +H+ V+ R+ +K + + GDT VL+C G P Sbjct: 2114 EGDYTCYAQNTLGKDEMK---VHLTVITAAPRIRQSNKTNKRIKAGDTAVLDC-EVTGDP 2169 Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196 +P ++W ++ R G+L I + D+G Y C+ARN +G ++ + L Sbjct: 2170 KPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVKLLDSGEYVCVARNPSGD-DTKMYKL 2228 Query: 197 KIHIKPYLITG---PEDVVAQTG---SSVTFQCRVGGDPLPDVLWRRSAG-GGNMPL--G 247 + KP LI G V+ T S F CR G P P+V+W P Sbjct: 2229 DVVSKPPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGS 2288 Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD----PPSINLSPNSVN 303 R+ V +G+L + NV L+D ++ C A N G L V + P N + Sbjct: 2289 RITVHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIV 2348 Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363 + G C+ G P P + W + N T G Y +G + I+ T + Sbjct: 2349 AQLGKSTALNCSVDGNPPPEIIW-ILPNGTRFSNG--PQSYQYLIASNGSFI--ISKTTR 2403 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN-QTLPIKSMAVFPCTAI 422 D+ C+A N G ++ KL + + + P I+T P + + +S+++ C + Sbjct: 2404 EDA-GKYRCAARNKVG--YIE-KLVIL-EIGQKPVILTYAPGTVKGISGESLSLH-CVSD 2457 Query: 423 CTPEPIIAWYFEGEALIQNHRRN----VTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 P+P I W ++ + N + ++GTLV+K+ D G Y C A + G Sbjct: 2458 GIPKPNIKWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVG 2513 Score = 91.9 bits (218), Expect = 1e-16 Identities = 70/273 (25%), Positives = 117/273 (42%), Gaps = 21/273 (7%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSD---THRSILPAGGLFFLRATHGRVHSDAGVYWCEA 87 LNC G+P P I W S+ +++ ++ + G F + T DAG Y C A Sbjct: 2357 LNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKT---TREDAGKYRCAA 2413 Query: 88 TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147 N G + L + P + + G+++ L C+ G P+PN+ W Sbjct: 2414 RNKVGYIE-KLVILEIGQKPVILTYAPGTVKGISGESLSLHCVSD-GIPKPNIKWTMPSG 2471 Query: 148 TLL----FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY 203 ++ +G +H D G LVI++A D G Y C A+N+ G + + + P Sbjct: 2472 YVVDRPQINGKYILH--DNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPR 2529 Query: 204 LIT-GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR------SAGGGNMPLGRVKVLDDGS 256 + P +V +TG++ C G P P++ W S G ++ G+ Sbjct: 2530 ITNRPPRSIVTRTGAAFQLHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGT 2589 Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 L + N +D G Y C A+N +G+ A+ Y+ V Sbjct: 2590 LVIQNPQTSDSGIYKCTAKNPLGSDYAATYIQV 2622 Score = 55.2 bits (127), Expect = 1e-05 Identities = 50/167 (29%), Positives = 74/167 (44%), Gaps = 13/167 (7%) Query: 122 GDTVVLECLPPRGSPEPNVYWK-KNGQTL---LFDGDSRMHLVDGGNLVIQDARQTDAGR 177 G TV L C P +G P P+V W +G + D R+ + G L +Q A D G Sbjct: 490 GGTVGLNC-PGQGDPTPHVDWLLADGSKVRAPYVSEDGRILIDKSGKLELQMADSFDTGV 548 Query: 178 YQCIARNAAGTRESAIATLKIHI-KPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDV 233 Y CI+ N ++ I T +I + +P + E+ + T G ++ C G P + Sbjct: 549 YHCISSNYD---DADILTYRITVVEPLVEAYQENGIHHTVFIGETLDLPCHSTGIPDASI 605 Query: 234 LWRRSAGGGNMPLGR-VKVLDDGSLRLDNVILADEGEYSCEAENSVG 279 W R KVL++G+LR+ V D+G Y C A N G Sbjct: 606 SWVIPGNNVLYQSSRDKKVLNNGTLRILQVTPKDQGYYRCVAANPSG 652 Score = 53.6 bits (123), Expect = 3e-05 Identities = 51/188 (27%), Positives = 77/188 (40%), Gaps = 15/188 (7%) Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGG-NMPL----GRVKVLDDGSLRLDNVILADEGEY 270 G +V C GDP P V W + G P GR+ + G L L D G Y Sbjct: 490 GGTVGLNCPGQGDPTPHVDWLLADGSKVRAPYVSEDGRILIDKSGKLELQMADSFDTGVY 549 Query: 271 SCEAENSVGAVSASGYLTVYDPPSINLSPNSVN--VESGNVARFTCTATGRPEPTMFWSV 328 C + N A + +TV +P N ++ V G C +TG P+ ++ W + Sbjct: 550 HCISSNYDDADILTYRITVVEPLVEAYQENGIHHTVFIGETLDLPCHSTGIPDASISWVI 609 Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT 388 GN + SRDK V + T+ + T K+ + C A N +G F+ +++ Sbjct: 610 PGNNVLY--QSSRDK----KVLNNGTLRILQVTPKD--QGYYRCVAANPSGVDFLIFQVS 661 Query: 389 VTSDDDRP 396 V RP Sbjct: 662 VKMKGQRP 669 Score = 50.8 bits (116), Expect = 2e-04 Identities = 46/175 (26%), Positives = 71/175 (40%), Gaps = 11/175 (6%) Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRWY-----KGGVLVVSDTHRSILPAGGLFFLRATH 73 L+ TV LNC G P+P + W K VS+ R ++ G L+ Sbjct: 483 LEHTVLVGGTVGLNCPGQGDPTPHVDWLLADGSKVRAPYVSEDGRILIDKSGKLELQMAD 542 Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAV-LREEFRLEPESKQSAQGDTVVLECLPP 132 D GVY C ++N Y A + V L E ++ G+T+ L C Sbjct: 543 S---FDTGVYHCISSN-YDDADILTYRITVVEPLVEAYQENGIHHTVFIGETLDLPC-HS 597 Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 G P+ ++ W G +L+ +++ G L I D G Y+C+A N +G Sbjct: 598 TGIPDASISWVIPGNNVLYQSSRDKKVLNNGTLRILQVTPKDQGYYRCVAANPSG 652 Score = 49.6 bits (113), Expect = 5e-04 Identities = 43/170 (25%), Positives = 68/170 (40%), Gaps = 9/170 (5%) Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 G C G P P + W + + P +S D + D L + D D+ Sbjct: 490 GGTVGLNCPGQGDPTPHVDWLLADGSKVRAPYVSED---GRILIDKSGKLELQMADSFDT 546 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426 C + NY + + ++TV + NG + T+ I PC + P+ Sbjct: 547 -GVYHCISSNYDDADILTYRITVV--EPLVEAYQENG-IHHTVFIGETLDLPCHSTGIPD 602 Query: 427 PIIAWYFEGE-ALIQNHR-RNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 I+W G L Q+ R + V N+GTL + + D G Y CVA++ G Sbjct: 603 ASISWVIPGNNVLYQSSRDKKVLNNGTLRILQVTPKDQGYYRCVAANPSG 652 >UniRef50_Q49AK4 Cluster: DCC protein; n=9; Euteleostomi|Rep: DCC protein - Homo sapiens (Human) Length = 772 Score = 155 bits (376), Expect = 7e-36 Identities = 178/699 (25%), Positives = 278/699 (39%), Gaps = 78/699 (11%) Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA-----RQTDAGRYQCIAR-NAAGTRES 191 P + WKK+G L D R + G+L+IQ+ + D G YQC A +G+ S Sbjct: 4 PVIKWKKDGIHLALGMDERKQQLSNGSLLIQNILHSRHHKPDEGLYQCEASLGDSGSIIS 63 Query: 192 AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG--RV 249 A + + ++ E V A G +V +C V G+P+P + W+++ G RV Sbjct: 64 RTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRV 123 Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSAS-GYLTVYDPPSINLS------PNSV 302 VL G+L++ + D G Y C A N + + + + + P ++ P++V Sbjct: 124 VVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEVRILSDPGLHRQLYFLQRPSNV 183 Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362 G A +G P P+ W + G I + KY ++ G +L N TD Sbjct: 184 VAIEGKDAVLEGCVSGYPPPSFTW-LRGEEVI---QLRSKKY---SLLGGSNLLISNVTD 236 Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTA 421 + T V + N S+ +LTV PP N PSN +SM + F CT Sbjct: 237 DDSGMYTCVVTYKNENISA--SAELTVLV-----PPWFLNHPSN-LYAYESMDIEFECTV 288 Query: 422 ICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481 P P + W G+ +I + + L + + KSD G Y CVA + G S Sbjct: 289 SGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQ 348 Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541 L+V P P+ S LP P + V+ V LSW + +I + V Sbjct: 349 LIVPKPAIPS--------SSVLPSAPRDVVPVLVSSRFVRLSWRPPAE-AKGNIQTFTV- 398 Query: 542 VFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPV 601 FSRE G+N R + + V +L P Y F V N GP Sbjct: 399 FFSRE---GDNRER-----ALNTTQPGSLQLTVGNLKPEAMYTFRVVAYNEW---GPGES 447 Query: 602 SDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYL 661 S + V G VE ++A +I + WE Y Sbjct: 448 SQPIKVATQPELQVPGP-----------------VENLQAVSTSPTSILITWE--PPAYA 488 Query: 662 EGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNS 721 G +R + + I D +++ L+K+T+Y + + + G ++ Sbjct: 489 NGPVQGYRLFCTEVSTGKEQNI--EVDGLSYKLEGLKKFTEYSLRFLAYNRYGPGVSTDD 546 Query: 722 RVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKS 781 TL DVP PP N+ + ++N+ ++ + W PP QNG ITGY + Sbjct: 547 ITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEME 606 Query: 782 MVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGP 820 + N + + T L G YS Q++A T+ G GP Sbjct: 607 TLEPNNLWY-----LFTGLEKGSQYSFQVSAMTVNGTGP 640 Score = 143 bits (346), Expect = 3e-32 Identities = 123/390 (31%), Positives = 173/390 (44%), Gaps = 34/390 (8%) Query: 41 PAIRWYKGGVLVV--SDTHRSILPAGGLFFLRATHGRVHS-DAGVYWCEAT-NSYGTARS 96 P I+W K G+ + D + L G L H R H D G+Y CEA+ G+ S Sbjct: 4 PVIKWKKDGIHLALGMDERKQQLSNGSLLIQNILHSRHHKPDEGLYQCEASLGDSGSIIS 63 Query: 97 RNATLHVA-VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL-FDGD 154 R A + VA LR F + ES + GDTV+L+C G P P ++W+KN Q L GD Sbjct: 64 RTAKVAVAGPLR--FLSQTESVTAFMGDTVLLKC-EVIGEPMPTIHWQKNQQDLTPIPGD 120 Query: 155 SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI------HIKPYLITGP 208 SR+ ++ G L I + D G Y+C ARN A +R A ++I H + Y + P Sbjct: 121 SRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEVRILSDPGLHRQLYFLQRP 180 Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268 +VVA G + V G P P W R + + +L +L + NV D G Sbjct: 181 SNVVAIEGKDAVLEGCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSG 240 Query: 269 EYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328 Y+C +SAS LTV PP P+++ F CT +G+P PT+ W Sbjct: 241 MYTCVVTYKNENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMK 300 Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT 388 G+ ++ P D + G + L I K+D C A N AG++ +L Sbjct: 301 NGD--VVIPS---DYFQIV----GGSNLRILGVVKSD-EGFYQCVAENEAGNAQTSAQLI 350 Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418 V P P I PS+ LP V P Sbjct: 351 V------PKPAI---PSSSVLPSAPRDVVP 371 Score = 118 bits (283), Expect = 1e-24 Identities = 83/298 (27%), Positives = 134/298 (44%), Gaps = 20/298 (6%) Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG---VLVVSDTHRSILPAGGLFFLRA 71 + Q VT L C G P P I W K + D+ +LP+G L R Sbjct: 77 LSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRL 136 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHV----AVLREEFRLE-PESKQSAQGDTVV 126 G D G+Y C A N + A + + + R+ + L+ P + + +G V Sbjct: 137 QPG----DIGIYRCSARNPASSRTGNEAEVRILSDPGLHRQLYFLQRPSNVVAIEGKDAV 192 Query: 127 LE-CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 LE C+ G P P+ W + G+ ++ + L+ G NL+I + D+G Y C+ Sbjct: 193 LEGCV--SGYPPPSFTWLR-GEEVIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVV-TY 248 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 SA A L + + P+ + P ++ A + F+C V G P+P V W ++ G +P Sbjct: 249 KNENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKN-GDVVIP 307 Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP--PSINLSPNS 301 +++ +LR+ V+ +DEG Y C AEN G S L V P PS ++ P++ Sbjct: 308 SDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSA 365 Score = 69.7 bits (163), Expect = 4e-10 Identities = 59/211 (27%), Positives = 87/211 (41%), Gaps = 14/211 (6%) Query: 13 YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAGGLFFLRA 71 Y +++P +V + A L G P P+ W +G V+ + S+L L Sbjct: 175 YFLQRPSNVVAIEGKDAVLEGCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNV 234 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131 T D+G+Y C T S +A L V V F P + + + + EC Sbjct: 235 T----DDDSGMYTCVVTYKNENI-SASAELTVLV-PPWFLNHPSNLYAYESMDIEFEC-T 287 Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191 G P P V W KNG ++ +V G NL I ++D G YQC+A N AG ++ Sbjct: 288 VSGKPVPTVNWMKNGDVVI--PSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQT 345 Query: 192 AIATL----KIHIKPYLITGPEDVVAQTGSS 218 + + I L + P DVV SS Sbjct: 346 SAQLIVPKPAIPSSSVLPSAPRDVVPVLVSS 376 Score = 46.0 bits (104), Expect = 0.006 Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 4/85 (4%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P+ + P ++ C G P P + W K G +V+ + I+ L L Sbjct: 265 PWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRIL-- 322 Query: 72 THGRVHSDAGVYWCEATNSYGTARS 96 G V SD G Y C A N G A++ Sbjct: 323 --GVVKSDEGFYQCVAENEAGNAQT 345 >UniRef50_UPI0000E47894 Cluster: PREDICTED: similar to scavenger receptor cysteine-rich protein type 12 precursor; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to scavenger receptor cysteine-rich protein type 12 precursor - Strongylocentrotus purpuratus Length = 2255 Score = 155 bits (375), Expect = 9e-36 Identities = 118/397 (29%), Positives = 177/397 (44%), Gaps = 33/397 (8%) Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAI---RWYKGGVL-----VVS 54 D V S P E+P + T+ A C+A G P+P + W K G + S Sbjct: 1769 DCTVVSSYPPTFAEEPKNRTINAGSGALFRCKADGRPTPRVTVSSWLKDGQPLSQRDLSS 1828 Query: 55 DTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP 114 R +G L F+R D+G Y C N+ G S +A L V P Sbjct: 1829 GRLRVYTSSGSLQFVRTR----REDSGNYTCVIRNTQGVNTS-SAFLVVKERPHIMSTHP 1883 Query: 115 ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTD 174 +++ G+T L C+ G PE V W++NGQ L+ G+ + G L+I+D R D Sbjct: 1884 DTR--ILGETAELGCIVV-GLPESTVSWRRNGQPLM--GERFQSFGENGTLLIRDVRLED 1938 Query: 175 AGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL 234 G Y+C+A N G + A L ++ P + GP+++ +TGS V+ C V G PLP++ Sbjct: 1939 NGMYECVAVNQLG-EDQASVKLTVYEVPTFLEGPQEMEVRTGSDVSIPCVVSGVPLPEIT 1997 Query: 235 WRRSAGGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293 W++ G + L GRV +L+D +L + D GEY+C A N V + L + PP Sbjct: 1998 WKKD--GQMISLNGRVTILEDNTLVIHKSQREDMGEYACIASNKVQTSARIAKLLIIGPP 2055 Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353 I +P + +G CT G P + W G + D+ H V D Sbjct: 2056 HITEAPTNQTRVTGETVVLPCTVIGAYNPVVTWQHNGEDVV------NDERH-LMVDDS- 2107 Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT 390 LT+ D D D VC+A N G+ +++T Sbjct: 2108 --LTVTDVDPADG-GLYVCTATNTEGAVSANAYVSIT 2141 Score = 147 bits (355), Expect = 2e-33 Identities = 114/391 (29%), Positives = 172/391 (43%), Gaps = 28/391 (7%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVY---WKKNGQTL----LFDGDSRMHLVDG 162 F EP+++ G + C G P P V W K+GQ L L G R++ Sbjct: 1780 FAEEPKNRTINAGSGALFRCKAD-GRPTPRVTVSSWLKDGQPLSQRDLSSGRLRVY-TSS 1837 Query: 163 GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQ 222 G+L R+ D+G Y C+ RN G S+ A L + +P++++ D G + Sbjct: 1838 GSLQFVRTRREDSGNYTCVIRNTQGVNTSS-AFLVVKERPHIMSTHPDTRI-LGETAELG 1895 Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVS 282 C V G P V WRR+ G M ++G+L + +V L D G Y C A N +G Sbjct: 1896 CIVVGLPESTVSWRRN-GQPLMGERFQSFGENGTLLIRDVRLEDNGMYECVAVNQLGEDQ 1954 Query: 283 ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRD 342 AS LTVY+ P+ P + V +G+ C +G P P + W +G + I G Sbjct: 1955 ASVKLTVYEVPTFLEGPQEMEVRTGSDVSIPCVVSGVPLPEITWKKDG-QMISLNG---- 2009 Query: 343 KYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN 402 T + D L I+ + + D C A N +S KL + PP IT Sbjct: 2010 --RVTILED--NTLVIHKSQRED-MGEYACIASNKVQTSARIAKLLIIG-----PPHITE 2059 Query: 403 GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDS 462 P+NQT V PCT I P++ W GE ++ N R++ D +L + D+D +D Sbjct: 2060 APTNQTRVTGETVVLPCTVIGAYNPVVTWQHNGEDVV-NDERHLMVDDSLTVTDVDPADG 2118 Query: 463 GTYTCVASSRHGKYVWSGALLVDSPINPNIH 493 G Y C A++ G + + + P+ H Sbjct: 2119 GLYVCTATNTEGAVSANAYVSITGPVRLGQH 2149 Score = 60.1 bits (139), Expect = 4e-07 Identities = 58/222 (26%), Positives = 93/222 (41%), Gaps = 18/222 (8%) Query: 259 LDNVILADEGEYSCEA-ENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317 +D V ++D+ E E VG ++ Y PP+ P + + +G+ A F C A Sbjct: 1744 VDCVTVSDDQSVCLECPEGQVGNGIDCTVVSSY-PPTFAEEPKNRTINAGSGALFRCKAD 1802 Query: 318 GRPEPTM---FWSVEGNRTIIFPGMSRD-KYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373 GRP P + W +G P RD V+ L T + DS N C Sbjct: 1803 GRPTPRVTVSSWLKDGQ-----PLSQRDLSSGRLRVYTSSGSLQFVRTRREDSGN-YTCV 1856 Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF 433 N G + L V P I++ P + L A C + PE ++W Sbjct: 1857 IRNTQGVNTSSAFLVV----KERPHIMSTHPDTRIL--GETAELGCIVVGLPESTVSWRR 1910 Query: 434 EGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 G+ L+ ++ +GTL+++D+ D+G Y CVA ++ G+ Sbjct: 1911 NGQPLMGERFQSFGENGTLLIRDVRLEDNGMYECVAVNQLGE 1952 >UniRef50_UPI0000D8E943 Cluster: Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).; n=1; Danio rerio|Rep: Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2). - Danio rerio Length = 1862 Score = 155 bits (375), Expect = 9e-36 Identities = 209/836 (25%), Positives = 341/836 (40%), Gaps = 79/836 (9%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I ++T + +NCR G P +I+WYK G+L+ D HR ++ G L+ Sbjct: 338 PPSIRAMRNITAVAGRNTFINCRVIGYPYYSIKWYKDGMLL-PDNHRQVVYENGT--LKL 394 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNA--TLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 + + D G Y C + S+ T+ V L + F P S G + + C Sbjct: 395 SDVQKGMDEGAYLCSVLIQPQLSISQTVYVTVKVPPLIQPFDFPPTSI----GKLMYIAC 450 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCIARNAA 186 + G + W+K+GQ ++ G + + + +L I G Y CIA N A Sbjct: 451 VVSSGDMPIRITWRKDGQEIV-SGTAGVTIETKEFMSSLQISKVSLKHNGNYTCIASNDA 509 Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN--- 243 T S L + + P P + G S C V G P P V+W+ + G GN Sbjct: 510 ATVSSE-RQLIVTVPPRFRVQPNNQDGIYGKSEVLNCSVEGYPPPKVVWKHAKGIGNPQQ 568 Query: 244 ---MPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLS 298 +PL GR+++L +GSL + +V+ D G Y C+A N VG+ +S S LTV P I Sbjct: 569 YHPVPLTGRIQILSNGSLLIRHVLEEDRGYYLCQASNGVGSDISKSMMLTVKIPAMITSH 628 Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV-----FDGV 353 PN+ G CTA G + W E T+I P + +Y T + + Sbjct: 629 PNTTMAIKGQNKELNCTARGEYPIIIRW--ERGDTVIDPDRN-PRYSITTSPNEKSDEVI 685 Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413 + L + ++ DS C A+N G +LTV D PP + ++++ ++ Sbjct: 686 STLKLKPAERGDSV-FFSCHAINSYGEGRGLIQLTVQEPPD-PPELEVREVKDRSMNLRW 743 Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNV--TNDGTLVLKDLDKSDSGTYTCVASS 471 F +I T I +++ R + TN+ ++ +L + + + + Sbjct: 744 TQRFDGNSIITSYDIEYKNKSDPWELKHATRKISPTNNQANIV-ELHPASVYSIRMYSYN 802 Query: 472 RHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK-I 530 + G+ S L + + P GPP + I +T S+ ++W K + Sbjct: 803 KIGRSQASKELTISTEEAPP------------DGPPMEVILQPMTSQSIRVTWKAPKKEL 850 Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590 + I GYQ+ RE G+N V + Y + +L Y +V+ Sbjct: 851 QNGVIRGYQIGY--RENGPGSN---GQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAF 905 Query: 591 NSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIK 650 N G +GPS + T +D V + +T V EA S+ + Sbjct: 906 NRAG-TGPSSSEINATTLED---------VPSQPPQNVRAIT---VTSDEAVITWSEPPR 952 Query: 651 LMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPF 710 + LN L+G + F L EM+ I + + E+ L K+T Y ++ + Sbjct: 953 MT---LNGV-LKGYRVVFWSLYPDGEWGEMQNITTTREQ--VELKGLEKFTNYSVQVLAY 1006 Query: 711 YKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVV 770 + +G SN QT +D P GPP I+ + ++V + W PP NGII Y + Sbjct: 1007 TQAGDGVRSNVLYIQTREDHP-GPPAGIKAVPSSASSVVVSWLPP--VKPNGIIRKYTI- 1062 Query: 771 VNWLDVPANKSMVAINTTVHQATSLI-MTNLTSGVSYSVQIAAETIIGLGPFSQKV 825 + P + + + +T+LT G Y + AA T G G S+KV Sbjct: 1063 --YCSSPGSGQPAPSEYEANPELLIYRITHLTRGQQYLIWAAAVTTAGRGNISEKV 1116 Score = 117 bits (282), Expect = 2e-24 Identities = 116/455 (25%), Positives = 184/455 (40%), Gaps = 39/455 (8%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 L C A G P+P IRW K G + +D+ + G L + R+ D+G Y CE TNS Sbjct: 78 LPCIASGYPNPTIRWLKDGRPLPADSRWTRRLTG----LTISDLRLE-DSGNYICEVTNS 132 Query: 91 YGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149 +G S+ T H+ V+ L P++ ++ TV+L C +GSP V W +N + + Sbjct: 133 FG---SKEVTGHLNVIEPLRVTLSPKNLKTGISSTVILSCAV-QGSPHFTVSWFRNTEPI 188 Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209 + D + L I A++ +G YQC A T + L P +++ Sbjct: 189 VPDQHFSIQGAHNETLFITAAQKRHSGAYQCFATRKGQTAQDFSIILLEDGTPRIVSSFS 248 Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWR---RSAGGGNMPLGRVKVLDDGS----LRLDNV 262 + V G + C G P P + W + L DGS + + N Sbjct: 249 ERVVAPGEPFSLMCAAKGAPPPTITWTLDDEPVARDSAHRASQYTLSDGSTVSHVNVTNP 308 Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEP 322 + D G Y C A NS G+ + V PPSI N + +G C G P Sbjct: 309 QIRDGGVYRCAARNSAGSAEYQARINVRGPPSIRAMRN-ITAVAGRNTFINCRVIGYPYY 367 Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382 ++ W +G ++ P H V++ T L ++D K +CS + S Sbjct: 368 SIKWYKDG---MLLP-----DNHRQVVYENGT-LKLSDVQKGMDEGAYLCSVLIQPQLS- 417 Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGEALIQN 441 + + VT + PP+I T I + C PI I W +G+ ++ Sbjct: 418 ISQTVYVTV---KVPPLIQPFDFPPT-SIGKLMYIACVVSSGDMPIRITWRKDGQEIVSG 473 Query: 442 HRRNVTND-----GTLVLKDLDKSDSGTYTCVASS 471 VT + +L + + +G YTC+AS+ Sbjct: 474 -TAGVTIETKEFMSSLQISKVSLKHNGNYTCIASN 507 Score = 102 bits (244), Expect = 7e-20 Identities = 138/561 (24%), Positives = 222/561 (39%), Gaps = 73/561 (13%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT-HRS----ILPAGGL 66 P I+ + VA +P +L C A G+P P I W V D+ HR+ + + Sbjct: 241 PRIVSSFSERVVAPGEPFSLMCAAKGAPPPTITWTLDDEPVARDSAHRASQYTLSDGSTV 300 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126 + T+ ++ D GVY C A NS G+A + + V + + G Sbjct: 301 SHVNVTNPQIR-DGGVYRCAARNSAGSAEYQ---ARINVRGPPSIRAMRNITAVAGRNTF 356 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ-TDAGRYQC--IAR 183 + C G P ++ W K+G +L + R + + G L + D ++ D G Y C + + Sbjct: 357 INCRVI-GYPYYSIKWYKDG--MLLPDNHRQVVYENGTLKLSDVQKGMDEGAYLCSVLIQ 413 Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRRSAGGG 242 ++ T+K+ P LI + G + C V +P + WR+ G Sbjct: 414 PQLSISQTVYVTVKV---PPLIQPFDFPPTSIGKLMYIACVVSSGDMPIRITWRKD--GQ 468 Query: 243 NMPLGRVKVLDD-----GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297 + G V + SL++ V L G Y+C A N VS+ L V PP + Sbjct: 469 EIVSGTAGVTIETKEFMSSLQISKVSLKHNGNYTCIASNDAATVSSERQLIVTVPPRFRV 528 Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 PN+ + G C+ G P P + W + + I P +YH + + +L+ Sbjct: 529 QPNNQDGIYGKSEVLNCSVEGYPPPKVVW--KHAKGIGNP----QQYHPVPLTGRIQILS 582 Query: 358 INDT----DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413 + R +C A N GS + + + P +IT+ P N T+ IK Sbjct: 583 NGSLLIRHVLEEDRGYYLCQASNGVGSDISKSMMLTV----KIPAMITSHP-NTTMAIKG 637 Query: 414 M-AVFPCTAICTPEPIIAWYFEGEALI---QNHRRNVTND---------GTLVLKDLDKS 460 CTA PII + G+ +I +N R ++T TL LK ++ Sbjct: 638 QNKELNCTA-RGEYPIIIRWERGDTVIDPDRNPRYSITTSPNEKSDEVISTLKLKPAERG 696 Query: 461 DSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSV 520 DS ++C A + +G+ L V P P PP + V D S+ Sbjct: 697 DSVFFSCHAINSYGEGRGLIQLTVQEP----------------PDPPELEV-REVKDRSM 739 Query: 521 TLSWSQNNKIGSSSILGYQVE 541 L W+Q G+S I Y +E Sbjct: 740 NLRWTQRFD-GNSIITSYDIE 759 Score = 83.0 bits (196), Expect = 4e-14 Identities = 87/357 (24%), Positives = 143/357 (40%), Gaps = 31/357 (8%) Query: 155 SRMHLVDGGNLVIQDARQTDA-GRYQCIARN--AAGTRESAIATLKI----HIKPYLITG 207 +R L G L I D ++ DA Y+CI ++ + TR+S A L + P ++ Sbjct: 5 NRFFLTSYGALYISDVQKEDALSTYRCITKHKYSGETRQSNGARLSVLDPTESTPSVMDS 64 Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267 + Q G S+ C G P P + W + G +P L + ++ L D Sbjct: 65 FQSGEVQVGRSIELPCIASGYPNPTIRWLKD--GRPLPADSRWTRRLTGLTISDLRLEDS 122 Query: 268 GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327 G Y CE NS G+ +G+L V +P + LSP ++ + +C G P T+ W Sbjct: 123 GNYICEVTNSFGSKEVTGHLNVIEPLRVTLSPKNLKTGISSTVILSCAVQGSPHFTVSWF 182 Query: 328 VEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387 N I P D++ + T L I K S C A ++ Sbjct: 183 --RNTEPIVP----DQHFSIQGAHNET-LFITAAQKRHS-GAYQCFATRKGQTA---QDF 231 Query: 388 TVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN--HRRN 445 ++ +D P I+++ P + ++ C A P P I W + E + ++ HR + Sbjct: 232 SIILLEDGTPRIVSSFSERVVAPGEPFSLM-CAAKGAPPPTITWTLDDEPVARDSAHRAS 290 Query: 446 --VTNDGTLV----LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFR 496 +DG+ V + + D G Y C A + G + + V P P+I R Sbjct: 291 QYTLSDGSTVSHVNVTNPQIRDGGVYRCAARNSAGSAEYQARINVRGP--PSIRAMR 345 Score = 66.1 bits (154), Expect = 6e-09 Identities = 71/267 (26%), Positives = 109/267 (40%), Gaps = 29/267 (10%) Query: 269 EYSCEAENSVGAVSASGYLTVYDP----PSINLSPNSVNVESGNVARFTCTATGRPEPTM 324 +YS E S GA L+V DP PS+ S S V+ G C A+G P PT+ Sbjct: 36 KYSGETRQSNGA-----RLSVLDPTESTPSVMDSFQSGEVQVGRSIELPCIASGYPNPTI 90 Query: 325 FWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR 384 W +G P SR T LTI+D DS N +C N GS V Sbjct: 91 RWLKDGRP---LPADSRWTRRLTG-------LTISDLRLEDSGN-YICEVTNSFGSKEVT 139 Query: 385 GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR 444 G L V P +T P N I S + C +P ++W+ E ++ + Sbjct: 140 GHLNVIE-----PLRVTLSPKNLKTGISSTVILSCAVQGSPHFTVSWFRNTEPIVPDQHF 194 Query: 445 NV--TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSS 502 ++ ++ TL + K SG Y C A +R G+ ++++ P I + V + Sbjct: 195 SIQGAHNETLFITAAQKRHSGAYQCFA-TRKGQTAQDFSIILLEDGTPRIVSSFSERVVA 253 Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNK 529 PG P + T++W+ +++ Sbjct: 254 -PGEPFSLMCAAKGAPPPTITWTLDDE 279 Score = 65.7 bits (153), Expect = 7e-09 Identities = 52/191 (27%), Positives = 85/191 (44%), Gaps = 11/191 (5%) Query: 643 PIDSKTIKLMWEI----LNFYYLEGLFIYFRPLD-NITIEYEMKTILHSNDVSGFEITSL 697 P+ S++I++ W+ L + G I +R +Y + + + D + + +L Sbjct: 833 PMTSQSIRVTWKAPKKELQNGVIRGYQIGYRENGPGSNGQYSIVEMKATGDSEVYTLDNL 892 Query: 698 RKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPEL 757 +K+ +Y + F + G S+ A TL+DVP PP N+ + + + WS P Sbjct: 893 KKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPQNVRAITVTSDEAVITWSEPPR 952 Query: 758 QLQNGIITGYNVVVNWLDVPANK--SMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETI 815 NG++ GY VV W P + M I TT Q + L +YSVQ+ A T Sbjct: 953 MTLNGVLKGYRVVF-WSLYPDGEWGEMQNITTTREQVE---LKGLEKFTNYSVQVLAYTQ 1008 Query: 816 IGLGPFSQKVY 826 G G S +Y Sbjct: 1009 AGDGVRSNVLY 1019 Score = 61.7 bits (143), Expect = 1e-07 Identities = 52/176 (29%), Positives = 83/176 (47%), Gaps = 23/176 (13%) Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429 I +AV AG + K+TV P I++ G + T +K + + PC+++ P P I Sbjct: 1099 IWAAAVTTAGRGNISEKVTVEPAGKAPAKILSFGGTVTTPWMKEVRL-PCSSVGEPTPTI 1157 Query: 430 AWYFEGE----ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485 W + E + Q+ RN+ ++GTLVL+ + DSG YTC A++ G LLV Sbjct: 1158 KWTKDSEDTAIPVTQDGHRNILSNGTLVLRSVKAEDSGYYTCTATNTLGFDTIIVNLLVQ 1217 Query: 486 SPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541 P P P ++ T +S+TL+W + G SSI G+ ++ Sbjct: 1218 VP----------------PDQPRLTVSTTST-SSITLAWIPGDN-GGSSIRGFVLQ 1255 Score = 56.0 bits (129), Expect = 6e-06 Identities = 41/169 (24%), Positives = 70/169 (41%), Gaps = 8/169 (4%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753 I L + Y + + K + S T + PDGPP+ + + + + ++ + W Sbjct: 785 IVELHPASVYSIRMYSYNKIGRSQASKELTISTEEAPPDGPPMEVILQPMTSQSIRVTWK 844 Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMT--NLTSGVSYSVQIA 811 P+ +LQNG+I GY + + P + +I S + T NL Y V + Sbjct: 845 APKKELQNGVIRGYQIGYR-ENGPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQ 903 Query: 812 AETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETW 860 A G GP S ++ + + D+ S+ P N V D + TW Sbjct: 904 AFNRAGTGPSSSEI-----NATTLEDVPSQPPQNVRAITVTSDEAVITW 947 Score = 45.2 bits (102), Expect = 0.011 Identities = 45/166 (27%), Positives = 68/166 (40%), Gaps = 15/166 (9%) Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190 P G P P+ Y + N + L++ HL G +I A T AGR + Sbjct: 1067 PGSGQPAPSEY-EANPELLIY---RITHLTRGQQYLIWAAAVTTAGRGNISEK--VTVEP 1120 Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL---G 247 + A KI +T P V C G+P P + W + + +P+ G Sbjct: 1121 AGKAPAKILSFGGTVTTP------WMKEVRLPCSSVGEPTPTIKWTKDSEDTAIPVTQDG 1174 Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293 +L +G+L L +V D G Y+C A N++G + L V PP Sbjct: 1175 HRNILSNGTLVLRSVKAEDSGYYTCTATNTLGFDTIIVNLLVQVPP 1220 Score = 44.0 bits (99), Expect = 0.025 Identities = 31/90 (34%), Positives = 44/90 (48%), Gaps = 9/90 (10%) Query: 8 SGEAPY-IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG----GVLVVSDTHRSILP 62 +G+AP I+ VT + L C + G P+P I+W K + V D HR+IL Sbjct: 1121 AGKAPAKILSFGGTVTTPWMKEVRLPCSSVGEPTPTIKWTKDSEDTAIPVTQDGHRNIL- 1179 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYG 92 + G LR+ D+G Y C ATN+ G Sbjct: 1180 SNGTLVLRSVKA---EDSGYYTCTATNTLG 1206 Score = 42.3 bits (95), Expect = 0.078 Identities = 38/153 (24%), Positives = 63/153 (41%), Gaps = 10/153 (6%) Query: 134 GSPEPNVYWKKNGQ--TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191 G P P + W K+ + + D +++ G LV++ + D+G Y C A N G ++ Sbjct: 1151 GEPTPTIKWTKDSEDTAIPVTQDGHRNILSNGTLVLRSVKAEDSGYYTCTATNTLGF-DT 1209 Query: 192 AIATLKIHIKPYLITGPEDVVAQTG-SSVTFQC---RVGGDPLPDVLWRRSAGGGNMPLG 247 I L + + P P V+ T SS+T GG + + + S Sbjct: 1210 IIVNLLVQVPP---DQPRLTVSTTSTSSITLAWIPGDNGGSSIRGFVLQYSVDNTEEWKD 1266 Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGA 280 + S +LDN+ + A+NSVGA Sbjct: 1267 VFISSSERSFKLDNLRCGTWYKVKLAAKNSVGA 1299 >UniRef50_A6BM71 Cluster: Connectin; n=8; Gallus gallus|Rep: Connectin - Gallus gallus (Chicken) Length = 8074 Score = 155 bits (375), Expect = 9e-36 Identities = 137/498 (27%), Positives = 208/498 (41%), Gaps = 30/498 (6%) Query: 2 SDDYVTSGEAPYIIEQPLDVT--VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRS 59 S ++T E P I++ LD + V +H C+ GGSP + WYKG + S Sbjct: 3266 STAFLTVTEPPRFIKK-LDSSRLVKQHDSTRYECKVGGSPEIKVTWYKGETEIHPSEKYS 3324 Query: 60 ILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS 119 + + L H D+G Y CEA N G+A S + +L V F +P Q+ Sbjct: 3325 MSFVDSVAVLEM-HNLSVEDSGDYSCEAQNPAGSA-STSTSLKVKA-PPAFTKKPHPVQT 3381 Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV----IQDARQTDA 175 +G V LEC +G+P + W K+ + + S+ + V N + I + D Sbjct: 3382 LKGSDVHLEC-ELQGTPPFQISWYKDKREIR---SSKKYKVMSENYLASIHILNVDTADV 3437 Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235 G Y C A N G+ +S I ++ + P + DV G ++ Q V G VLW Sbjct: 3438 GEYHCKAVNDVGS-DSCIGSVTLRAPPTFVKKLSDVTVVVGETIELQAAVEGAQPISVLW 3496 Query: 236 RRSAGGGNMPLGRVKVL---DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292 + G + + + SL++ N + G+Y C+ +N G LTV +P Sbjct: 3497 LKDKGEIIRESENLWISYSENVASLKIGNAEPTNAGKYICQIKNDAGFQECFAKLTVLEP 3556 Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352 I P V V +G+ CT G PE T W +GN +S D + + F+ Sbjct: 3557 AVIVEKPGPVKVTAGDSCTLECTVDGTPELTARWFKDGNE------LSTDHKYKISFFNK 3610 Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412 V+ L I + DS N G S L V+ D PP T + Sbjct: 3611 VSGLKILNAGLEDS-GEYTFEVKNSVGKSSCTASLQVS--DRIMPPSFTRKLKETYGQLG 3667 Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT-NDGTLVLK--DLDKSDSGTYTCVA 469 S AV C +P +++W+ +G+ + + T D T LK L +SD GTY+C A Sbjct: 3668 SSAVLECKVYGSPPILVSWFHDGQEITSGDKYQATLTDNTCSLKVNGLQESDMGTYSCTA 3727 Query: 470 SSRHGKYVWSGALLVDSP 487 ++ G S L V P Sbjct: 3728 TNVAGSDECSAFLSVREP 3745 Score = 139 bits (337), Expect = 4e-31 Identities = 136/541 (25%), Positives = 221/541 (40%), Gaps = 26/541 (4%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64 +++ E P +++P V + T GSP ++W++G + + +I Sbjct: 3739 FLSVREPPSFVKKPEPFNVLSGENITFTSIVKGSPPLEVKWFRGSIELAPGHKCNITLQD 3798 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR-EEFRLEPESKQSAQGD 123 + L + +G Y C+ +N G + T H+ V +F ++ +G Sbjct: 3799 SVAELELFDVQ-PLQSGDYTCQVSNEAGKI---SCTTHLFVKEPAKFVMKVNDLSVEKGK 3854 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIA 182 ++LEC G+P +V WKKNG L + + L I +++ D G+Y C Sbjct: 3855 NLILEC-TYTGTPPISVTWKKNGVILKHSEKCSITTTETSAILEIPNSKLEDQGQYSCHI 3913 Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR--SAG 240 N +G +++ + I PY +T E V G S + QC+V G P V W + + Sbjct: 3914 ENDSG-QDNCHGAITILEPPYFVTPLEPVQVTVGDSASLQCQVAGTPEMIVSWYKGDTKL 3972 Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINL 297 G + +L V D GEY C+ EN+VG ++S LTV + PPS Sbjct: 3973 RGTATVKMHFKNQVATLVFSQVDSDDSGEYICKVENTVGEATSSSLLTVQERKLPPSFTR 4032 Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 V+ G F C G + W + R + D T+ D V +L Sbjct: 4033 KLRDVHETVGLPVTFDCGIAGSEPIEVSWFKDNVR------VKEDYNVHTSFIDNVAILQ 4086 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417 I TDK+ C+A N G++ GKL +T + + PP + I A F Sbjct: 4087 ILKTDKS-LMGQYTCTASNAIGTASSSGKLVLT--EGKTPPFFDTPITPVDGIIGESADF 4143 Query: 418 PCTAICTPEPIIAWYFEGEALIQ--NHRRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 C T + W + + + N++ + V N L + +D+ DSG YTC AS+ G Sbjct: 4144 ECHISGTQPIRVTWAKDNQEIRTGGNYQISYVENTAHLTILRVDRGDSGKYTCYASNEVG 4203 Query: 475 KYVWSGALLVDSPINPNIHFFRAAD-VSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSS 533 K + L V P + ++ V G K +T+SW +NN+ S Sbjct: 4204 KDSCTAQLNVKERKTPPTFTRKLSEAVEETEGNELKLEGRVAGSQPLTVSWYKNNQEVHS 4263 Query: 534 S 534 S Sbjct: 4264 S 4264 Score = 133 bits (321), Expect = 3e-29 Identities = 128/483 (26%), Positives = 194/483 (40%), Gaps = 29/483 (6%) Query: 17 QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV 76 +PL+V V + A C +P+ +WYK G + SI + L L +V Sbjct: 3190 EPLEVAV--NHVAKFTCEVETTPNVKFQWYKAGREIYDGDKYSIRSSNYLSTLEIPRPQV 3247 Query: 77 HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136 D G Y C+A+N +G+ S A L V + S+ Q D+ EC GSP Sbjct: 3248 -VDCGEYSCKASNQHGSV-SSTAFLTVTEPPRFIKKLDSSRLVKQHDSTRYEC-KVGGSP 3304 Query: 137 EPNVYWKKNGQTLLFDGDS-RMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194 E V W K G+T + + M VD L + + D+G Y C A+N AG+ S Sbjct: 3305 EIKVTWYK-GETEIHPSEKYSMSFVDSVAVLEMHNLSVEDSGDYSCEAQNPAGS-ASTST 3362 Query: 195 TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254 +LK+ P P V GS V +C + G P + W + + KV+ + Sbjct: 3363 SLKVKAPPAFTKKPHPVQTLKGSDVHLECELQGTPPFQISWYKDKREIRSS-KKYKVMSE 3421 Query: 255 ---GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVAR 311 S+ + NV AD GEY C+A N VG+ S G +T+ PP+ + V V G Sbjct: 3422 NYLASIHILNVDTADVGEYHCKAVNDVGSDSCIGSVTLRAPPTFVKKLSDVTVVVGETIE 3481 Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF-DGVTVLTINDTDKNDSRNTI 370 G ++ W + I R+ + + + V L I + + ++ Sbjct: 3482 LQAAVEGAQPISVLWLKDKGEII------RESENLWISYSENVASLKIGNAEPTNA-GKY 3534 Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA 430 +C N AG KLTV P +I P + CT TPE Sbjct: 3535 ICQIKNDAGFQECFAKLTVLE-----PAVIVEKPGPVKVTAGDSCTLECTVDGTPELTAR 3589 Query: 431 WYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 W+ +G L +H+ ++ L + + DSG YT + GK + +L V Sbjct: 3590 WFKDGNELSTDHKYKISFFNKVSGLKILNAGLEDSGEYTFEVKNSVGKSSCTASLQVSDR 3649 Query: 488 INP 490 I P Sbjct: 3650 IMP 3652 Score = 127 bits (306), Expect = 2e-27 Identities = 123/508 (24%), Positives = 195/508 (38%), Gaps = 22/508 (4%) Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88 A L C+ GSP + W+ G + S L+ +G SD G Y C AT Sbjct: 3670 AVLECKVYGSPPILVSWFHDGQEITSGDKYQATLTDNTCSLKV-NGLQESDMGTYSCTAT 3728 Query: 89 NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148 N G+ +A L V F +PE G+ + + +GSP V W + Sbjct: 3729 NVAGSDEC-SAFLSVRE-PPSFVKKPEPFNVLSGENITFTSIV-KGSPPLEVKWFRGSIE 3785 Query: 149 LLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG 207 L + L D L + D + +G Y C N AG + S L + + Sbjct: 3786 LAPGHKCNITLQDSVAELELFDVQPLQSGDYTCQVSNEAG-KISCTTHLFVKEPAKFVMK 3844 Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG--GGNMPLGRVKVLDDGSLRLDNVILA 265 D+ + G ++ +C G P V W+++ + L + N L Sbjct: 3845 VNDLSVEKGKNLILECTYTGTPPISVTWKKNGVILKHSEKCSITTTETSAILEIPNSKLE 3904 Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325 D+G+YSC EN G + G +T+ +PP V V G+ A C G PE + Sbjct: 3905 DQGQYSCHIENDSGQDNCHGAITILEPPYFVTPLEPVQVTVGDSASLQCQVAGTPEMIVS 3964 Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385 W +G+ + G + K H + V L + D +DS +C N G + Sbjct: 3965 W-YKGDTKL--RGTATVKMHFK---NQVATLVFSQVDSDDS-GEYICKVENTVGEATSSS 4017 Query: 386 KLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGEALIQN--- 441 LTV + + PP T + + F C I EPI ++W+ + + ++ Sbjct: 4018 LLTV--QERKLPPSFTRKLRDVHETVGLPVTFDC-GIAGSEPIEVSWFKDNVRVKEDYNV 4074 Query: 442 HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVS 501 H + N L + DKS G YTC AS+ G SG L++ P V Sbjct: 4075 HTSFIDNVAILQILKTDKSLMGQYTCTASNAIGTASSSGKLVLTEGKTPPFFDTPITPVD 4134 Query: 502 SLPGPPTKPITHNVTDTSVTLSWSQNNK 529 + G H + ++W+++N+ Sbjct: 4135 GIIGESADFECHISGTQPIRVTWAKDNQ 4162 Score = 120 bits (290), Expect = 2e-25 Identities = 121/495 (24%), Positives = 201/495 (40%), Gaps = 45/495 (9%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 D++V + + L C G+P ++ W K GV++ SI L + ++ D Sbjct: 3847 DLSVEKGKNLILECTYTGTPPISVTWKKNGVILKHSEKCSITTTETSAILEIPNSKLE-D 3905 Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVLECLPPRGSPEP 138 G Y C N G A + +L + + P E Q GD+ L+C G+PE Sbjct: 3906 QGQYSCHIENDSGQDNCHGA---ITILEPPYFVTPLEPVQVTVGDSASLQC-QVAGTPEM 3961 Query: 139 NVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAG--TRESAIAT 195 V W K L +MH + LV D+G Y C N G T S + Sbjct: 3962 IVSWYKGDTKLRGTATVKMHFKNQVATLVFSQVDSDDSGEYICKVENTVGEATSSSLLTV 4021 Query: 196 LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255 + + P DV G VTF C + G +V W + V+V +D Sbjct: 4022 QERKLPPSFTRKLRDVHETVGLPVTFDCGIAGSEPIEVSWFKD---------NVRVKEDY 4072 Query: 256 SLR---LDNVIL-----ADE---GEYSCEAENSVGAVSASGYLTVYD---PPSINLSPNS 301 ++ +DNV + D+ G+Y+C A N++G S+SG L + + PP + Sbjct: 4073 NVHTSFIDNVAILQILKTDKSLMGQYTCTASNAIGTASSSGKLVLTEGKTPPFFDTPITP 4132 Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361 V+ G A F C +G + W+ + N+ I G + Y + LTI Sbjct: 4133 VDGIIGESADFECHISGTQPIRVTWAKD-NQEIRTGGNYQISY-----VENTAHLTILRV 4186 Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421 D+ DS C A N G +L V + + PP T S + + Sbjct: 4187 DRGDS-GKYTCYASNEVGKDSCTAQLNVK--ERKTPPTFTRKLSEAVEETEGNELKLEGR 4243 Query: 422 ICTPEPI-IAWYFEGEALIQNHRRNVT-NDGTLVL--KDLDKSDSGTYTCVASSRHGKYV 477 + +P+ ++WY + + + ++ + TL+L K + +SD+G YTC S+ G + Sbjct: 4244 VAGSQPLTVSWYKNNQEVHSSPHCEISFKNNTLLLHIKSVGQSDAGLYTCKVSNEAGSVL 4303 Query: 478 WSGALLVDSPINPNI 492 + ++++ P P + Sbjct: 4304 CTSSVVIREPKKPPV 4318 Score = 109 bits (263), Expect = 3e-22 Identities = 125/494 (25%), Positives = 199/494 (40%), Gaps = 31/494 (6%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAG 64 VT P +++ DVTV + L G+ ++ W K G ++ + I + Sbjct: 3457 VTLRAPPTFVKKLSDVTVVVGETIELQAAVEGAQPISVLWLKDKGEIIRESENLWISYSE 3516 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTAR--SRNATLHVAVLREEFRLEPESKQSAQG 122 + L+ + ++AG Y C+ N G ++ L AV+ E+ P + G Sbjct: 3517 NVASLKIGNAEP-TNAGKYICQIKNDAGFQECFAKLTVLEPAVIVEK----PGPVKVTAG 3571 Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCI 181 D+ LEC G+PE W K+G L D ++ + L I +A D+G Y Sbjct: 3572 DSCTLECTVD-GTPELTARWFKDGNELSTDHKYKISFFNKVSGLKILNAGLEDSGEYTFE 3630 Query: 182 ARNAAGTRESAIATLKI--HIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238 +N+ G + S A+L++ I P T ++ Q GSS +C+V G P V W Sbjct: 3631 VKNSVG-KSSCTASLQVSDRIMPPSFTRKLKETYGQLGSSAVLECKVYGSPPILVSWFHD 3689 Query: 239 AGGGNMPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296 L D SL+++ + +D G YSC A N G+ S +L+V +PPS Sbjct: 3690 GQEITSGDKYQATLTDNTCSLKVNGLQESDMGTYSCTATNVAGSDECSAFLSVREPPSFV 3749 Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356 P NV SG FT G P + W G+ + PG K + T + D V L Sbjct: 3750 KKPEPFNVLSGENITFTSIVKGSPPLEVKW-FRGSIELA-PG---HKCNIT-LQDSVAEL 3803 Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416 + D S C N AG L V + P ++ ++ + Sbjct: 3804 ELFDVQPLQS-GDYTCQVSNEAGKISCTTHLFV-----KEPAKFVMKVNDLSVEKGKNLI 3857 Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS---DSGTYTCVASSRH 473 CT TP + W G L + + ++T T + ++ S D G Y+C + Sbjct: 3858 LECTYTGTPPISVTWKKNGVILKHSEKCSITTTETSAILEIPNSKLEDQGQYSCHIENDS 3917 Query: 474 GKYVWSGALLVDSP 487 G+ GA+ + P Sbjct: 3918 GQDNCHGAITILEP 3931 Score = 103 bits (246), Expect = 4e-20 Identities = 122/486 (25%), Positives = 197/486 (40%), Gaps = 41/486 (8%) Query: 28 PATLNCRAGGSPSPAIRWYKGGVLVVSD--THRSILPAGGLFFLRATHGRVHSDAGVYWC 85 P T +C GS + W+K V V D H S + + + T S G Y C Sbjct: 4044 PVTFDCGIAGSEPIEVSWFKDNVRVKEDYNVHTSFIDNVAILQILKTD---KSLMGQYTC 4100 Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPESK-QSAQGDTVVLECLPPRGSPEPNVYWKK 144 A+N+ GTA S + F P + G++ EC G+ V W K Sbjct: 4101 TASNAIGTASSSGKLVLTEGKTPPFFDTPITPVDGIIGESADFEC-HISGTQPIRVTWAK 4159 Query: 145 NGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK-- 201 + Q + G+ ++ V+ +L I + D+G+Y C A N G ++S A L + + Sbjct: 4160 DNQEIRTGGNYQISYVENTAHLTILRVDRGDSGKYTCYASNEVG-KDSCTAQLNVKERKT 4218 Query: 202 -PYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLW-RRSAGGGNMPLGRVKVLDDGSL- 257 P + V +T G+ + + RV G V W + + + P + ++ L Sbjct: 4219 PPTFTRKLSEAVEETEGNELKLEGRVAGSQPLTVSWYKNNQEVHSSPHCEISFKNNTLLL 4278 Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP---PSINLSPNSVNVESGNVARFTC 314 + +V +D G Y+C+ N G+V + + + +P P + E G+ + +C Sbjct: 4279 HIKSVGQSDAGLYTCKVSNEAGSVLCTSSVVIREPKKPPVFDQPLQPAATEEGDTLQLSC 4338 Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF-DGVTVLTINDTDKNDSRNTIVCS 373 G EP ++ R I R + F +GV +L + K+DS VC Sbjct: 4339 HVRGS-EPIRIQWLKAGREI------RASERCSFSFANGVALLELAAVTKSDS-GEYVCK 4390 Query: 374 AVNYAGSSFVRGKLTVTSD----------DDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423 A N AG+ R K+TV D + P + + K++A F Sbjct: 4391 ASNVAGTDTCRSKVTVKEKAALVSAAKKADIEGKLYFVSEPQSIKVMEKTVATFIAKVGG 4450 Query: 424 TPEPIIAWYF-EGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWS 479 P P + W + L Q R + G L +KD K+DSG Y CVA ++HG+ S Sbjct: 4451 DPIPNVKWMKGKWRQLNQGGRIIIQQRGDEAKLEIKDTTKTDSGLYKCVAFNQHGEIERS 4510 Query: 480 GALLVD 485 L V+ Sbjct: 4511 VNLQVE 4516 Score = 101 bits (241), Expect = 2e-19 Identities = 138/521 (26%), Positives = 202/521 (38%), Gaps = 55/521 (10%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64 YV + E P II++ TV +PA G P P + WYK + L Sbjct: 2959 YVNAPEPPQIIQELQPTTVESGKPARFCAIISGKPQPKVSWYKDDQQLSPGFKCKFLHDA 3018 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-----EFRLEPESKQS 119 + L D+ VY CEA N YG A + +A+L V + E + P + Sbjct: 3019 QEYTLLLIE-TFPEDSAVYTCEAKNDYGVA-TTSASLSVEIPEVVSPELEVPVYPPAVIV 3076 Query: 120 AQGDTVVLECLPPR-----GSPEPNVYWKKNGQTLLFDGDSRM-HLVDGGNLVIQDARQT 173 D V E R + V W + + RM D L I +A Sbjct: 3077 PLRDAVTSEGQSARFQCRVTGTDLKVSWYSKDREIKPSRFFRMTQFEDTYQLEIAEAYPE 3136 Query: 174 DAGRYQCIARNAAG-TRESAIATL-----------------KIHIKPYLITGPEDVVAQT 215 D G Y +A N+ G +AI L ++ + P L E + Sbjct: 3137 DEGTYTFVASNSVGQVTSTAILKLEAPEKIMYEKLEEEIEMEVKVAPILRRRLEPLEVAV 3196 Query: 216 GSSVTFQCRVGGDPLPDVLW----RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYS 271 F C V P W R G + L +L + + D GEYS Sbjct: 3197 NHVAKFTCEVETTPNVKFQWYKAGREIYDGDKYSIRSSNYL--STLEIPRPQVVDCGEYS 3254 Query: 272 CEAENSVGAVSASGYLTVYDPPS-INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330 C+A N G+VS++ +LTV +PP I +S V+ + R+ C G PE + W +G Sbjct: 3255 CKASNQHGSVSSTAFLTVTEPPRFIKKLDSSRLVKQHDSTRYECKVGGSPEIKVTW-YKG 3313 Query: 331 NRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT 390 T I P +KY + V D V VL +++ DS C A N AGS+ T T Sbjct: 3314 -ETEIHPS---EKYSMSFV-DSVAVLEMHNLSVEDS-GDYSCEAQNPAGSA-----STST 3362 Query: 391 SDDDRPPPIITNGPSN-QTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND 449 S + PP T P QTL S C TP I+WY + + + + V ++ Sbjct: 3363 SLKVKAPPAFTKKPHPVQTLK-GSDVHLECELQGTPPFQISWYKDKREIRSSKKYKVMSE 3421 Query: 450 GTLV---LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 L + ++D +D G Y C A + G G++ + +P Sbjct: 3422 NYLASIHILNVDTADVGEYHCKAVNDVGSDSCIGSVTLRAP 3462 Score = 101 bits (241), Expect = 2e-19 Identities = 123/491 (25%), Positives = 191/491 (38%), Gaps = 42/491 (8%) Query: 6 VTSGEAPYIIE--QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63 +T E PY + +P+ VTV A+L C+ G+P + WYKG + + Sbjct: 3926 ITILEPPYFVTPLEPVQVTVG--DSASLQCQVAGTPEMIVSWYKGDTKLRGTATVKMHFK 3983 Query: 64 GGLFFLRATHGRVHS-DAGVYWCEATNSYGTARSRN-ATLHVAVLREEFRLEPESKQSAQ 121 + L +V S D+G Y C+ N+ G A S + T+ L F + Sbjct: 3984 NQVATL--VFSQVDSDDSGEYICKVENTVGEATSSSLLTVQERKLPPSFTRKLRDVHETV 4041 Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTD---AGRY 178 G V +C GS V W K+ + D + +D N+ I +TD G+Y Sbjct: 4042 GLPVTFDC-GIAGSEPIEVSWFKDNVRVKEDYNVHTSFID--NVAILQILKTDKSLMGQY 4098 Query: 179 QCIARNAAGTRESA--IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 C A NA GT S+ + + P+ T V G S F+C + G V W Sbjct: 4099 TCTASNAIGTASSSGKLVLTEGKTPPFFDTPITPVDGIIGESADFECHISGTQPIRVTWA 4158 Query: 237 RS----AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD- 291 + GGN + V+ + L + V D G+Y+C A N VG S + L V + Sbjct: 4159 KDNQEIRTGGNYQISYVE--NTAHLTILRVDRGDSGKYTCYASNEVGKDSCTAQLNVKER 4216 Query: 292 --PPSINLS-PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348 PP+ +V GN + G T+ W + N+ + H Sbjct: 4217 KTPPTFTRKLSEAVEETEGNELKLEGRVAGSQPLTVSW-YKNNQEV------HSSPHCEI 4269 Query: 349 VFDGVTVLT-INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407 F T+L I ++D+ C N AGS + + + + PP+ + P Sbjct: 4270 SFKNNTLLLHIKSVGQSDA-GLYTCKVSNEAGSVLCTSSVVIR--EPKKPPVF-DQPLQP 4325 Query: 408 TLPIKSMAVFPCTAICTPEPI-IAWYFEGEALIQNHRRNVTNDGTLVLKDL---DKSDSG 463 + + + EPI I W G + + R + + + L +L KSDSG Sbjct: 4326 AATEEGDTLQLSCHVRGSEPIRIQWLKAGREIRASERCSFSFANGVALLELAAVTKSDSG 4385 Query: 464 TYTCVASSRHG 474 Y C AS+ G Sbjct: 4386 EYVCKASNVAG 4396 Score = 78.6 bits (185), Expect = 1e-12 Identities = 178/812 (21%), Positives = 299/812 (36%), Gaps = 98/812 (12%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 D V Q NC + +WYK G + I+ ++ LR ++ D Sbjct: 6885 DQEVNEGQEIIFNCEVNKEGAKE-KWYKNGEAIFDSAKYIIVQKDLVYTLRIRDTQL-KD 6942 Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRL-EP-ESKQSAQGDTVVLECLPPRGSPE 137 Y +N G +A L VL E R+ EP E ++ + TV C R + Sbjct: 6943 QATYSISLSNHRGEHAESSAAL--TVLEEGLRIVEPLEDIETMEKKTVTFWCKVNRLNA- 6999 Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195 + W KNG+ + F+ ++ +D +L+I+D D G Y A ++ ++A Sbjct: 7000 -TLKWTKNGEEITFN-KRILYKIDKYKHSLIIKDCGFKDEGEYTVTAG-----QDKSVAE 7052 Query: 196 LKIHIKPY-LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD- 253 L I P I +D F C++ + V W R+ G + G+ + Sbjct: 7053 LLITEAPADFIEHLQDQTVTEFDDAVFTCQLSKEKA-SVKWYRN--GREIKEGKKYQFEK 7109 Query: 254 DGSLR---LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310 DG+L + + L DE EYSC ++ + L V + P + P E+ Sbjct: 7110 DGNLHRLIIKDCRLDDECEYSCGVDDR----KSRARLFVEEIPVEIIRPPQDVYEAPGAD 7165 Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370 + + W N II G + + + + V I D+ + R Sbjct: 7166 VIFMAELNKDGVEVKWL--RNNMIIIQG-DKHQMMSEGKVHRLQVCEIKPRDQGEYRFI- 7221 Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA 430 A R KL + + P I G N + + + P Sbjct: 7222 -------AKDKEARAKLELAA-----APRIKTGDQNLVVDVGNPLTMTVPYDAYPRAEAE 7269 Query: 431 WYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490 W E+L T+ T + + KSD G Y V ++H + ++ IN Sbjct: 7270 WLKGEESLPTTTVDTTTDCTTFKIYEAKKSDKGRYKVVLRNKHAQ--------AEAFIN- 7320 Query: 491 NIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSG 550 +V +PGP + D V L+W + G S I+GY VE R + Sbjct: 7321 -------VEVIDVPGPVRNLEVTEIYDGEVGLAWQEPESDGGSKIIGYVVE---RRDI-- 7368 Query: 551 NNTPRNSRGWVVIARRVHQTHYVVKSLIP-GITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 + W+V+ Y V L G+ Y+F V N G P V Sbjct: 7369 -----KRKTWIVVTDHAENCEYTVTGLQKGGVEYLFRVSARNRVGTGEPVETERPV---- 7419 Query: 610 DSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFR 669 ++ S +E G + +E T ++ L WE + + Y Sbjct: 7420 EAKSKFEVPGPPQN---------------VEVTDVNRFGRTLTWEAPEYDGGSPITGYVI 7464 Query: 670 PLDN-ITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLD 728 L N +I++E ++++S +T + + +Y F + GKPS+ A + Sbjct: 7465 ELRNRASIKWEPTMTTGADELSAV-LTDVVENEEYFFRVRAQNMVGVGKPSHPTRAVKIT 7523 Query: 729 DVPDGPP--INIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN 786 D + P IN++ T+V L W PP L+ I GY ++ + +K + N Sbjct: 7524 DPIERPSGNINLDHSDQTKTSVQLTWEPP-LEDGGSPILGY--IIERKEEGTDK-WIRCN 7579 Query: 787 TTVHQATSLIMTNLTSGVSYSVQIAAETIIGL 818 + A + +T L +G SY +++AE G+ Sbjct: 7580 PKLVPACAFKVTGLKAGSSYYYRVSAENAAGV 7611 Score = 76.2 bits (179), Expect = 5e-12 Identities = 114/450 (25%), Positives = 172/450 (38%), Gaps = 58/450 (12%) Query: 77 HSDAGVY-WCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGS 135 +SDAG Y + N NA +++E L+P + +S + C G Sbjct: 2939 YSDAGEYTFVAGRNRSSVVLYVNAPEPPQIIQE---LQPTTVESGKPARF---CAIISGK 2992 Query: 136 PEPNVYWKKNGQTLLFDGDSR-MHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194 P+P V W K+ Q L + +H L++ + D+ Y C A+N G ++ A Sbjct: 2993 PQPKVSWYKDDQQLSPGFKCKFLHDAQEYTLLLIETFPEDSAVYTCEAKNDYGVATTS-A 3051 Query: 195 TLKIHIK-------------PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241 +L + I P +I D V G S FQCRV G L + + Sbjct: 3052 SLSVEIPEVVSPELEVPVYPPAVIVPLRDAVTSEGQSARFQCRVTGTDLKVSWYSKDREI 3111 Query: 242 GNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI----- 295 R+ +D L + DEG Y+ A NSVG V+++ L + P I Sbjct: 3112 KPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNSVGQVTSTAILKLEAPEKIMYEKL 3171 Query: 296 --------NLSP------NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341 ++P + V +VA+FTC P W G I+ G Sbjct: 3172 EEEIEMEVKVAPILRRRLEPLEVAVNHVAKFTCEVETTPNVKFQWYKAGRE--IYDG--- 3226 Query: 342 DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401 DKY + + ++ L I D C A N GS LTVT PP I Sbjct: 3227 DKYSIRS-SNYLSTLEIPRPQVVDC-GEYSCKASNQHGSVSSTAFLTVT----EPPRFIK 3280 Query: 402 NGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN----VTNDGTLVLKDL 457 S++ + + C +PE + WY +GE I + V + L + +L Sbjct: 3281 KLDSSRLVKQHDSTRYECKVGGSPEIKVTWY-KGETEIHPSEKYSMSFVDSVAVLEMHNL 3339 Query: 458 DKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 DSG Y+C A + G S +L V +P Sbjct: 3340 SVEDSGDYSCEAQNPAGSASTSTSLKVKAP 3369 Score = 66.9 bits (156), Expect = 3e-09 Identities = 109/462 (23%), Positives = 185/462 (40%), Gaps = 43/462 (9%) Query: 44 RWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103 +W K GV + S T + + L + DA Y A G A S +ATL+V Sbjct: 2727 KWLKNGVEIKS-TDKCQIRTKKLTHSLSIRNVHFGDAAEYSFVA----GKAAS-SATLYV 2780 Query: 104 AVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG 163 EFR + + + + EC P+ V W K+GQ L GD RM + Sbjct: 2781 EARHIEFRKHIKDIKVVEKKRAIFEC--EISEPDVQVQWMKDGQELQI-GD-RMKIQREK 2836 Query: 164 ---NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVT 220 L+I + +DAG+Y +A + + + I+ I V+ + + + Sbjct: 2837 YVHRLIIPSTKMSDAGQYTVVAGGNTSSANLIVEGRDVRIRS--IRKEIQVIERQRAEIE 2894 Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGSLRLDNVI---LADEGEYSCEAEN 276 F+ V D + + W + N R + + + ++ +D GEY+ A Sbjct: 2895 FE--VNEDDI-EPQWYKDGIEINFHYEERYSYVVERRIHRMSIFETTYSDAGEYTFVAGR 2951 Query: 277 SVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF 336 + +V Y+ +PP I VESG ARF +G+P+P + W + + + Sbjct: 2952 NRSSVVL--YVNAPEPPQIIQELQPTTVESGKPARFCAIISGKPQPKVSWYKDDQQ--LS 3007 Query: 337 PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP 396 PG H + T+L I +T DS C A N G + L+V + Sbjct: 3008 PGFKCKFLHDAQEY---TLLLI-ETFPEDSA-VYTCEAKNDYGVATTSASLSVEIPEVVS 3062 Query: 397 PPI-ITNGPSNQTLPIK-------SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN 448 P + + P +P++ A F C T + ++WY + + + +T Sbjct: 3063 PELEVPVYPPAVIVPLRDAVTSEGQSARFQCRVTGT-DLKVSWYSKDREIKPSRFFRMTQ 3121 Query: 449 -DGT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 + T L + + D GTYT VAS+ G+ + L +++P Sbjct: 3122 FEDTYQLEIAEAYPEDEGTYTFVASNSVGQVTSTAILKLEAP 3163 Score = 64.5 bits (150), Expect = 2e-08 Identities = 48/181 (26%), Positives = 85/181 (46%), Gaps = 13/181 (7%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVI 167 F L+P S + +QG T + L G P P YW NGQ ++ D ++ + + G +L+I Sbjct: 1187 FVLKPTSVKCSQGQTARFD-LKVVGRPMPETYWFHNGQQVVNDYTHKIVIKEDGTQSLII 1245 Query: 168 QDARQTDAGRYQCIARNAAGTRESAIATLKIH-----IKPYLITGPEDVVAQTGSSVTFQ 222 A D+G + IA+N AG + S TL + ++P + +V + GS + Sbjct: 1246 VPAMPEDSGEWAVIAQNRAG-KASVSVTLSVEAKEDLVRPRFVERLRNVSVKEGSRLHMA 1304 Query: 223 CRVGGDPLPDVLWRRSAG---GGNMPLGRVK-VLDDGSLRLDNVILADEGEYSCEAENSV 278 + G+P PD++W +++ P R++ +L +++ D Y+ A N Sbjct: 1305 VKATGNPNPDIVWLKNSDIIVPHKYPRIRIEGTKGAAALNIESTARQDAAWYTATAINKA 1364 Query: 279 G 279 G Sbjct: 1365 G 1365 Score = 62.9 bits (146), Expect = 5e-08 Identities = 114/469 (24%), Positives = 175/469 (37%), Gaps = 55/469 (11%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 PY + D + TL C S ++WYK G +V+ + SI GL + Sbjct: 5900 PYFTVKLQDYSALEKDDITLQCEL--SKDVPVKWYKDGEELVASSRISI-KTDGLRRILT 5956 Query: 72 THGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130 D GVY C S GT ++ N + +++ E L + G+T E Sbjct: 5957 IKKATEGDKGVYEC----SCGTDKTNCNIGVEPRLIKVERPLY--GVEVFVGETARFEI- 6009 Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGT 188 P+ + WK G+TL + + + DG L++ R G A NA Sbjct: 6010 -EISEPDVHPIWKLKGETLTPSPECEI-IEDGKKHILILHQGRLDMTGEVSFQAANA--- 6064 Query: 189 RESAIATLKIHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247 + A LK+ P + P DV F+C V +P W + P Sbjct: 6065 --KSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGTQEIT-PDE 6120 Query: 248 RVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP-NSVN 303 R +++ DG+ L + +V DE +Y EAE+ S L + ++P V Sbjct: 6121 RFEIISDGTKHALIIKSVAFDDEAKYMFEAEDK----RTSAKLIIEGIRLKFITPLKDVT 6176 Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGN-RTIIFPGMSRD-KYHATAVFDGVTVLTINDT 361 + A FT + P +++ + T M+ D K+H + D LTI+DT Sbjct: 6177 KKERETAVFTVELSHENIPVVWFKNDQRLHTSKVVSMTDDGKFHTLTIKD----LTIDDT 6232 Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421 + V G S KLTV D P T + T K + C Sbjct: 6233 SQ---------IRVEAMGKSS-EAKLTVLEGD----PYFTGKLQDYTAVEKDEVILQCEI 6278 Query: 422 ICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTC 467 P+ W +G+ + + + DG L+LK K D G YTC Sbjct: 6279 SKADAPV-KWMKDGKPITPSKNVVIKADGKKRILILKKALKKDIGQYTC 6326 Score = 60.9 bits (141), Expect = 2e-07 Identities = 53/206 (25%), Positives = 84/206 (40%), Gaps = 13/206 (6%) Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW-RRSAGGGNMPLGRVKVLDDG--SL 257 KP + P V G + F +V G P+P+ W N ++ + +DG SL Sbjct: 1184 KPVFVLKPTSVKCSQGQTARFDLKVVGRPMPETYWFHNGQQVVNDYTHKIVIKEDGTQSL 1243 Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP-----PSINLSPNSVNVESGNVARF 312 + + D GE++ A+N G S S L+V P +V+V+ G+ Sbjct: 1244 IIVPAMPEDSGEWAVIAQNRAGKASVSVTLSVEAKEDLVRPRFVERLRNVSVKEGSRLHM 1303 Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372 ATG P P + W ++ + I+ R + T G L I T + D+ Sbjct: 1304 AVKATGNPNPDIVW-LKNSDIIVPHKYPRIRIEGT---KGAAALNIESTARQDAA-WYTA 1358 Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPP 398 +A+N AG R K+ V + P P Sbjct: 1359 TAINKAGRDTTRCKVNVEVEHAEPEP 1384 Score = 58.0 bits (134), Expect = 1e-06 Identities = 105/481 (21%), Positives = 182/481 (37%), Gaps = 54/481 (11%) Query: 13 YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRAT 72 Y + +P + V AT + GG P P ++W KG ++ R I+ G Sbjct: 4426 YFVSEPQSIKVMEKTVATFIAKVGGDPIPNVKWMKGKWRQLNQGGRIIIQQRGDEAKLEI 4485 Query: 73 HGRVHSDAGVYWCEATNSYGTARSRNATLHV-----AVLREEFRLE----PESKQSAQGD 123 +D+G+Y C A N +G R+ L V V+ E+ R + P K+ + Sbjct: 4486 KDTTKTDSGLYKCVAFNQHGEI-ERSVNLQVEERKQEVVEEDVRGKLKRIPTKKKEDEEQ 4544 Query: 124 TV-VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182 T+ +LE L E Y + G T D R L+ L ++ R+ ++ R + Sbjct: 4545 TIDILELLKNVDPKEYEKYARMYGIT-----DFR-GLLQAFEL-LKQTREEESHRLEIEL 4597 Query: 183 RNAAGTRESAIATLKIHIKPYLI-TGP-------EDVVAQTGSSVTFQCRVG-GDPLPDV 233 A + L I+ L T P E+ T F+C + P + Sbjct: 4598 TEKAQKEDQEFEELVAFIQQRLTQTEPVTLIRDIENQTVLTDEDAIFECEIKINYPEIKL 4657 Query: 234 LWRRSAGG-GNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291 W + + ++K+ D L++ N L D+G Y G AS LTV + Sbjct: 4658 SWYKGTQKLDSSDKYKIKIEGDRHILKIKNCQLEDQGNYRIVC----GPHIASARLTVIE 4713 Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 P++ + + GN +C + P W G R I G ++T V D Sbjct: 4714 -PAVERHLHDTTFKEGNTCTLSCQFS-IPNAKSQWYRNG-RPIKIGGR-----YSTQVSD 4765 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411 V L I D + + + C N ++ LT+ ++ P T N + Sbjct: 4766 KVHKLIIKDV-RTEDQGQYTCKLDNLETTA----DLTIEAE----PIQFTKSIQNIVVSE 4816 Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCV 468 A F C + + ++ WY L ++ + + ++G + + ++ D G Y+ + Sbjct: 4817 HQSATFEC-EVSFDDAVVTWYKGPTELTESPKYSFRSEGRCHYMTIHNVTAEDEGVYSVI 4875 Query: 469 A 469 A Sbjct: 4876 A 4876 Score = 56.8 bits (131), Expect = 3e-06 Identities = 107/439 (24%), Positives = 165/439 (37%), Gaps = 48/439 (10%) Query: 43 IRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLH 102 ++W+K G+ + I+ G L + + D Y CEA TAR+ Sbjct: 6642 VKWFKDGI-EIEKAEYDIISKGAERILVISKC-LFDDEAEYACEAK----TARTSGL--- 6692 Query: 103 VAVLREE--FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV 160 + V+ EE F + + +TV L C P V W K G + DG ++ Sbjct: 6693 LTVIEEEAVFTKNLHDLEVNENETVRLIC--EISKPNAEVTWFK-GDEEVPDGGRFEYIS 6749 Query: 161 DGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSS 218 DG LVI++A DAG+Y C +++ T + + L +T P+++ G Sbjct: 6750 DGRKRILVIRNAHPEDAGKYTCKLPSSSTTGKLTVHELAAE----FLTRPQNLEVLEGDK 6805 Query: 219 VTFQCRVGGDPLP-DVLWRRSAGGGNMPLGRVKVLDDGSLR---LDNVILADEGEYSCEA 274 F C V + + LW + P + ++ DG R + + ++ D G+Y+ Sbjct: 6806 AEFACSVSKEAITVQWLWGDTV---LEPGDKYDIISDGKKRTLVVKDSVVGDAGKYTV-- 6860 Query: 275 ENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334 VG A+ LTV + S V G F C ++ N Sbjct: 6861 --MVGEAKATARLTVIEKTQDYNSLKDQEVNEGQEIIFNCEVNKEGAKEKWYK---NGEA 6915 Query: 335 IFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGS-SFVRGKLTVTSDD 393 IF KY D V L I DT D + T S N+ G + LTV + Sbjct: 6916 IFDSA---KY-IIVQKDLVYTLRIRDTQLKD-QATYSISLSNHRGEHAESSAALTVLEEG 6970 Query: 394 DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND---G 450 R I+ +T+ K F C + + W GE + N R D Sbjct: 6971 LR---IVEPLEDIETME-KKTVTFWC-KVNRLNATLKWTKNGEEITFNKRILYKIDKYKH 7025 Query: 451 TLVLKDLDKSDSGTYTCVA 469 +L++KD D G YT A Sbjct: 7026 SLIIKDCGFKDEGEYTVTA 7044 Score = 54.4 bits (125), Expect = 2e-05 Identities = 35/129 (27%), Positives = 59/129 (45%), Gaps = 7/129 (5%) Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA---GGGNMPLGRVKVLDD-GSLRLDNVIL 264 + VVA GS+ TF+ + G P+P+V W R +P ++ D L + +V Sbjct: 13 QSVVALEGSAATFEAHISGFPVPEVSWYRDGQVLSAATLPGVQISFSDGRAKLVIPSVTE 72 Query: 265 ADEGEYSCEAENSVGAVSASGYLTV---YDPPSINLSPNSVNVESGNVARFTCTATGRPE 321 A+ G Y+ +A N G +++ L V PP+ + S+ G+ R TG P Sbjct: 73 ANSGRYTIQATNGSGQATSTAELLVTAGTAPPNFSQRLQSMTARQGSQVRLDVRVTGIPT 132 Query: 322 PTMFWSVEG 330 P + + +G Sbjct: 133 PVVKFYRDG 141 Score = 54.4 bits (125), Expect = 2e-05 Identities = 51/211 (24%), Positives = 77/211 (36%), Gaps = 14/211 (6%) Query: 271 SCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330 SC + +Y P + L P SV G ARF GRP P +W G Sbjct: 1164 SCSPARRLDETDEGQLERLYKPVFV-LKPTSVKCSQGQTARFDLKVVGRPMPETYWFHNG 1222 Query: 331 NRTIIFPGMSRDKYHATAV-FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389 + + D H + DG L I DS V A N AG + V L+V Sbjct: 1223 QQVV------NDYTHKIVIKEDGTQSLIIVPAMPEDSGEWAVI-AQNRAGKASVSVTLSV 1275 Query: 390 TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND 449 + +D P N ++ S A P P I W + ++ + + + Sbjct: 1276 EAKEDLVRPRFVERLRNVSVKEGSRLHMAVKATGNPNPDIVWLKNSDIIVPHKYPRIRIE 1335 Query: 450 GT-----LVLKDLDKSDSGTYTCVASSRHGK 475 GT L ++ + D+ YT A ++ G+ Sbjct: 1336 GTKGAAALNIESTARQDAAWYTATAINKAGR 1366 Score = 50.4 bits (115), Expect = 3e-04 Identities = 47/164 (28%), Positives = 68/164 (41%), Gaps = 9/164 (5%) Query: 134 GSPEPNVYWKKNGQTLLFDG--DSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRE 190 G P P V W ++GQ L ++ DG LVI + ++GRY A N +G Sbjct: 31 GFPVPEVSWYRDGQVLSAATLPGVQISFSDGRAKLVIPSVTEANSGRYTIQATNGSGQAT 90 Query: 191 SAIATLKIH--IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248 S L P + + A+ GS V RV G P P V + R G Sbjct: 91 STAELLVTAGTAPPNFSQRLQSMTARQGSQVRLDVRVTGIPTPVVKFYRD-GVEIQSSPD 149 Query: 249 VKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 ++L +G SL + D G YS A N+VG +++ L + Sbjct: 150 FQILQEGDLYSLIIAEAYPEDSGTYSVNATNNVGRATSTAELLI 193 Score = 50.0 bits (114), Expect = 4e-04 Identities = 47/197 (23%), Positives = 83/197 (42%), Gaps = 10/197 (5%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-THRSILPAGGLFFLR 70 P + +P V ++ Q A + + G P P W+ G VV+D TH+ ++ G L Sbjct: 1185 PVFVLKPTSVKCSQGQTARFDLKVVGRPMPETYWFHNGQQVVNDYTHKIVIKEDGTQSLI 1244 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR---LEPESKQSAQGDTVVL 127 + D+G + A N G A S + TL V + R +E S + + + Sbjct: 1245 IVPA-MPEDSGEWAVIAQNRAGKA-SVSVTLSVEAKEDLVRPRFVERLRNVSVKEGSRLH 1302 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL---VDGGNLVIQDARQTDAGRYQCIARN 184 + G+P P++ W KN ++ R+ + L I+ + DA Y A N Sbjct: 1303 MAVKATGNPNPDIVWLKNSDIIVPHKYPRIRIEGTKGAAALNIESTARQDAAWYTATAIN 1362 Query: 185 AAGTRESAIATLKIHIK 201 AG R++ + + ++ Sbjct: 1363 KAG-RDTTRCKVNVEVE 1378 Score = 48.4 bits (110), Expect = 0.001 Identities = 60/220 (27%), Positives = 93/220 (42%), Gaps = 18/220 (8%) Query: 17 QPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75 QPL VA AT G P P + WY+ G ++ + T LP + F Sbjct: 10 QPLQSVVALEGSAATFEAHISGFPVPEVSWYRDGQVLSAAT----LPGVQISFSDGRAKL 65 Query: 76 V-----HSDAGVYWCEATNSYGTARSRNATLHVA-VLREEFRLEPESKQSAQGDTVVLEC 129 V +++G Y +ATN G A S L A F +S + QG V L+ Sbjct: 66 VIPSVTEANSGRYTIQATNGSGQATSTAELLVTAGTAPPNFSQRLQSMTARQGSQVRLD- 124 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAG 187 + G P P V + ++G + D ++ L +G +L+I +A D+G Y A N G Sbjct: 125 VRVTGIPTPVVKFYRDGVEIQSSPDFQI-LQEGDLYSLIIAEAYPEDSGTYSVNATNNVG 183 Query: 188 TRESAIATLKIHIKPYLITG--PEDVVAQTGSSVTFQCRV 225 R ++ A L I + + + +V+ S T Q R+ Sbjct: 184 -RATSTAELLIQGEEEAVPAKKTKTIVSTAQISQTRQARI 222 Score = 48.4 bits (110), Expect = 0.001 Identities = 32/91 (35%), Positives = 49/91 (53%), Gaps = 8/91 (8%) Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKV---LDDG 255 + P+ I P G S+ F+C+VGG+P P VLW++ GG + G R KV + G Sbjct: 825 VPPFFIRKPVVHKLIEGGSIIFECQVGGNPKPHVLWKK--GGVPLTTGYRYKVSYKRETG 882 Query: 256 SLRLD-NVILADE-GEYSCEAENSVGAVSAS 284 +L+ ++ AD+ GEY+ N G SA+ Sbjct: 883 ECKLEISMTFADDAGEYTIVIRNKFGEASAT 913 Score = 47.2 bits (107), Expect = 0.003 Identities = 63/272 (23%), Positives = 97/272 (35%), Gaps = 23/272 (8%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPAG 64 +T E +I + TV + A C P + WYKG + S I G Sbjct: 4619 LTQTEPVTLIRDIENQTVLTDEDAIFECEIKINYPEIKLSWYKGTQKLDSSDKYKIKIEG 4678 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124 L+ + ++ D G Y +AR + V+ +G+T Sbjct: 4679 DRHILKIKNCQLE-DQGNYRIVCGPHIASAR-------LTVIEPAVERHLHDTTFKEGNT 4730 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIAR 183 L C P W +NG+ + G + D + L+I+D R D G+Y C Sbjct: 4731 CTLSC--QFSIPNAKSQWYRNGRPIKIGGRYSTQVSDKVHKLIIKDVRTEDQGQYTCKLD 4788 Query: 184 NAAGTRESAIATLKIHIKPYLIT-GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242 N T A L I +P T +++V S TF+C V D ++ Sbjct: 4789 NLETT-----ADLTIEAEPIQFTKSIQNIVVSEHQSATFECEVSFDDAVVTWYKGPTELT 4843 Query: 243 NMPLGRVKVLDDGS---LRLDNVILADEGEYS 271 P + +G + + NV DEG YS Sbjct: 4844 ESP--KYSFRSEGRCHYMTIHNVTAEDEGVYS 4873 Score = 46.8 bits (106), Expect = 0.004 Identities = 28/90 (31%), Positives = 38/90 (42%), Gaps = 2/90 (2%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL-- 259 P L+ G ++ G SVT +C + G P P V W R + G RL Sbjct: 690 PTLVWGLKNKTVTEGESVTLECHISGHPQPTVTWYREDYKIESSMDFQITFKAGLARLVI 749 Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTV 289 D G ++C A N G+VS S +L V Sbjct: 750 REAFAEDSGRFTCTATNKAGSVSTSCHLHV 779 Score = 46.0 bits (104), Expect = 0.006 Identities = 28/88 (31%), Positives = 45/88 (51%), Gaps = 5/88 (5%) Query: 115 ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQT 173 ++K +G++V LEC G P+P V W + + D ++ G LVI++A Sbjct: 697 KNKTVTEGESVTLEC-HISGHPQPTVTWYREDYKIESSMDFQITFKAGLARLVIREAFAE 755 Query: 174 DAGRYQCIARNAAGTRESAIATLKIHIK 201 D+GR+ C A N AG S + +H+K Sbjct: 756 DSGRFTCTATNKAG---SVSTSCHLHVK 780 Score = 45.6 bits (103), Expect = 0.008 Identities = 82/377 (21%), Positives = 138/377 (36%), Gaps = 32/377 (8%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 PY + D T L C + +P ++W K G ++ + ++ A G + Sbjct: 6255 PYFTGKLQDYTAVEKDEVILQCEISKADAP-VKWMKDGK-PITPSKNVVIKADGKKRILI 6312 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131 + D G Y C+ +A + ++R + +E ++A+ D + E Sbjct: 6313 LKKALKKDIGQYTCDCGTDQTSANLNIEDRDIEIIRPLYSVEVIETETARFDIEISE--- 6369 Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRE 190 + WK G+ L D + + L + + R AG A NA + Sbjct: 6370 ----EGVHGNWKLKGEPLTESPDCEIKEEGKKHFLTLYNVRLDQAGGVDFQAANA---KS 6422 Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250 A +K + L+ +DV G S TF C + + +P V W G P +V Sbjct: 6423 GAHLRVKPRVIG-LLRPLKDVTVTAGESATFDCELSYEGIP-VEWYLQ-GKKLEPSDKVV 6479 Query: 251 VLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP-NSVNVES 306 +G +L L +V L D GE S A++ L V +PP P VE Sbjct: 6480 TRAEGRAHTLILRDVKLTDAGEVSLTAKD----FRTQANLFVKEPPVEFTKPLEDQTVEE 6535 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 A C + R + W G + + K + V L I+ +D+ Sbjct: 6536 EATAILECEVS-RENAKVKWFKNGEE------IHKTKKYDIISEGRVRKLIIHGCTLDDA 6588 Query: 367 RNTIVCSAVNYAGSSFV 383 + T C A ++ S F+ Sbjct: 6589 K-TYTCDAKDFKTSCFL 6604 Score = 45.2 bits (102), Expect = 0.011 Identities = 33/89 (37%), Positives = 45/89 (50%), Gaps = 8/89 (8%) Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---RVKVLDDG--SLRLDNVILADEGEY 270 G+ VTF C+ G PLP + W + G + G ++VL DG SLRL V+ DEG Y Sbjct: 1049 GTGVTFHCKTTGYPLPKIAWYKD--GKRIRHGERYHMEVLQDGSASLRLPVVLPEDEGIY 1106 Query: 271 SCEAENSVGAVSASGYLTVYDPPSINLSP 299 + A N G S L V +P + +P Sbjct: 1107 TVFASNMKGNAICSAKLYV-EPVAPTATP 1134 Score = 44.8 bits (101), Expect = 0.015 Identities = 47/198 (23%), Positives = 79/198 (39%), Gaps = 16/198 (8%) Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGN--RTIIFPGMSRDKYHATAVF 350 P+ SV G+ A F +G P P + W +G PG+ + Sbjct: 6 PTFTQPLQSVVALEGSAATFEAHISGFPVPEVSWYRDGQVLSAATLPGVQ------ISFS 59 Query: 351 DGVTVLTIND-TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409 DG L I T+ N R TI A N +G + +L VT+ PP + + T Sbjct: 60 DGRAKLVIPSVTEANSGRYTI--QATNGSGQATSTAELLVTAGT--APPNFSQRLQSMTA 115 Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYT 466 S P P++ +Y +G + + + +G +L++ + DSGTY+ Sbjct: 116 RQGSQVRLDVRVTGIPTPVVKFYRDGVEIQSSPDFQILQEGDLYSLIIAEAYPEDSGTYS 175 Query: 467 CVASSRHGKYVWSGALLV 484 A++ G+ + LL+ Sbjct: 176 VNATNNVGRATSTAELLI 193 Score = 44.8 bits (101), Expect = 0.015 Identities = 28/87 (32%), Positives = 36/87 (41%), Gaps = 2/87 (2%) Query: 22 TVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAG 81 TV + TL C G P P + WY+ + S I GL L D+G Sbjct: 700 TVTEGESVTLECHISGHPQPTVTWYREDYKIESSMDFQITFKAGLARL-VIREAFAEDSG 758 Query: 82 VYWCEATNSYGTARSRNATLHVAVLRE 108 + C ATN G+ S + LHV V E Sbjct: 759 RFTCTATNKAGSV-STSCHLHVKVSEE 784 Score = 39.9 bits (89), Expect = 0.41 Identities = 84/327 (25%), Positives = 123/327 (37%), Gaps = 41/327 (12%) Query: 15 IEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFLRAT 72 I +PL D+TVA Q A C +P +W K G L ++D +R+ G+ Sbjct: 2349 ISKPLADLTVAESQRAVFECEVA-NPESEGQWLKNGKPLPMTDQYRA--ETDGVKRRLNI 2405 Query: 73 HGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131 D G Y SY A S+ +A LHV ++ + L+ + Q +E Sbjct: 2406 PAAKMDDMGEY------SYEIASSKTSAKLHVEAVKIKKTLKNLTVTETQEAVFSVELSH 2459 Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGTR 189 P W KNG L D V G L I+ TD Y Sbjct: 2460 P---DVKGALWIKNGVELE-SNDKYEISVKGTVHTLKIKHCVVTDESVYSFKLGKIGANA 2515 Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL--- 246 + T+KI I P+DV A + V+F+ V D +P V W N+ L Sbjct: 2516 RLHVETVKI------IKKPKDVTALENAVVSFELSVSHDTVP-VRWFHK----NVELKQS 2564 Query: 247 GRVKVLDD---GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303 + K++ L L N+ AD GEY+ VG + L V + I + S+ Sbjct: 2565 DKYKMISQRKVHKLMLHNISPADAGEYTA----FVGQLECKAKLFV-ETIHITKTMKSIE 2619 Query: 304 VESGNVARFTCTATGRPEPTMFWSVEG 330 + A F C + P++ W G Sbjct: 2620 IPETKTASFQCEVSHFNVPSV-WLKNG 2645 Score = 38.7 bits (86), Expect = 0.96 Identities = 21/81 (25%), Positives = 36/81 (44%), Gaps = 3/81 (3%) Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLV 453 PP + G N+T+ C P+P + WY E + + +T LV Sbjct: 689 PPTLVWGLKNKTVTEGESVTLECHISGHPQPTVTWYREDYKIESSMDFQITFKAGLARLV 748 Query: 454 LKDLDKSDSGTYTCVASSRHG 474 +++ DSG +TC A+++ G Sbjct: 749 IREAFAEDSGRFTCTATNKAG 769 Score = 38.3 bits (85), Expect = 1.3 Identities = 85/362 (23%), Positives = 135/362 (37%), Gaps = 43/362 (11%) Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV---DGGNLVIQDARQTDAGR 177 +GD V LE + E W K+G + R+H+V L+I+DA Q D+G Sbjct: 2096 EGDIVQLEVKVSVENVEG--VWMKDGHEI--QSSDRIHIVLDKQSHMLLIEDATQEDSGT 2151 Query: 178 YQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 Y + + G S + ++ +I +DV G+ +C+V + W Sbjct: 2152 Y---SFSIPGLELSTTGQVTVY-SVEIIVPLKDVHVVEGTKAILECKVSAPDVTSSKWYL 2207 Query: 238 SAGGGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294 + P RV+ + G+ L + +DEG Y VG V S +TV + Sbjct: 2208 N-DHQIKPDERVQAVCKGTKQRLVITRTHASDEGHYKL----MVGKVETSCNVTVEEIEI 2262 Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354 I + E+ NV+ F + W +G P + K A +T Sbjct: 2263 IRGLHDITCTETQNVS-FE-VELSHSGIDVIWHFKGQEIKAGP---KYKIEARGKIYKLT 2317 Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414 V+ + D+ + V YAG GKL V I+ ++ T+ Sbjct: 2318 VVKMMKDDEGE--------YVFYAGGKKTSGKLIVAGG------AISKPLADLTVAESQR 2363 Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTC-VAS 470 AVF C + PE W G+ L + DG L + D G Y+ +AS Sbjct: 2364 AVFEC-EVANPESEGQWLKNGKPLPMTDQYRAETDGVKRRLNIPAAKMDDMGEYSYEIAS 2422 Query: 471 SR 472 S+ Sbjct: 2423 SK 2424 Score = 38.3 bits (85), Expect = 1.3 Identities = 29/109 (26%), Positives = 42/109 (38%), Gaps = 10/109 (9%) Query: 501 SSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGW 560 +++P PP N T + L+W G + I GY VE R + W Sbjct: 7822 ATVPDPPENVKWRNPTSKGIFLTWEPPKYDGGARIKGYLVE----------KCQRGTDKW 7871 Query: 561 VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 + V +T V L G Y + V+ N G S PS +D + D Sbjct: 7872 EICGEPVIETKMEVTKLKEGEWYAYRVKALNRIGASKPSKPTDDIQAID 7920 Score = 37.9 bits (84), Expect = 1.7 Identities = 27/78 (34%), Positives = 36/78 (46%), Gaps = 5/78 (6%) Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHR--RNVTNDG--TLVLKDLDKSDSGTYTCVASSR 472 F C P P IAWY +G+ + R V DG +L L + D G YT AS+ Sbjct: 1054 FHCKTTGYPLPKIAWYKDGKRIRHGERYHMEVLQDGSASLRLPVVLPEDEGIYTVFASNM 1113 Query: 473 HGKYVWSGALLVDSPINP 490 G + S L V+ P+ P Sbjct: 1114 KGNAICSAKLYVE-PVAP 1130 Score = 37.9 bits (84), Expect = 1.7 Identities = 32/112 (28%), Positives = 55/112 (49%), Gaps = 11/112 (9%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAG--GSPSPAIRW-YKGGVLVVSDTHRSILPAGGL 66 + P+ ++ + + + PA CR G P+ + W + G L ++ R I G Sbjct: 1429 QKPFFKKKLTSLRLKQFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFG-- 1486 Query: 67 FFLRATHGRVHS-DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK 117 + +G +S D+GV C ATN YGT + +ATL ++++E L ES+ Sbjct: 1487 -YCSLDYGVAYSRDSGVITCRATNKYGTDHT-SATL---IVKDEKSLVEESQ 1533 Score = 37.9 bits (84), Expect = 1.7 Identities = 29/83 (34%), Positives = 37/83 (44%), Gaps = 3/83 (3%) Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLD 260 KP L+ PE G + F+CRV G PLP V W ++ R ++ DG LD Sbjct: 1568 KPELVLVPEPARVLEGETARFRCRVTGYPLPKVNWYLNSQLIRKS-KRFRLRYDGIHYLD 1626 Query: 261 NVILA--DEGEYSCEAENSVGAV 281 V D GE AEN G + Sbjct: 1627 IVDCKSYDTGEVKVTAENPEGFI 1649 Score = 37.9 bits (84), Expect = 1.7 Identities = 52/226 (23%), Positives = 81/226 (35%), Gaps = 7/226 (3%) Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGL 66 S EAP I E+ TVA+ A R G P P +W++ GV + +D P + Sbjct: 1801 SMEAPKIFERIQSQTVAQGTDAHFRVRVVGKPDPECQWFRNGVQIERTDRIYWYWPEDNV 1860 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV- 125 L D+ +A N G S L A F + + + D++ Sbjct: 1861 CEL-VIRDVTADDSASIMVKAVNIAGETSSHAFLLVQAKQLISFIQNLQDVVAKERDSMA 1919 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARN 184 EC P V W KNG + RMH + L + +DA Y C Sbjct: 1920 TFEC--ETSEPFIKVKWFKNGIEIHSGEKYRMHSDRKAHFLSVLAVEMSDADDYSCALVE 1977 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPL 230 + +A ++ + + I EDV + +C V + + Sbjct: 1978 DESVKTTAKLIVEGAVVEF-IKELEDVEVPESFTGELECEVSPEDI 2022 Score = 37.5 bits (83), Expect = 2.2 Identities = 28/109 (25%), Positives = 50/109 (45%), Gaps = 4/109 (3%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM-HLVDGG--NLV 166 F +P + +G +++ EC G+P+P+V WKK G L ++ + + G L Sbjct: 829 FIRKPVVHKLIEGGSIIFEC-QVGGNPKPHVLWKKGGVPLTTGYRYKVSYKRETGECKLE 887 Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT 215 I DAG Y + RN G + ++ L+ I ++++ QT Sbjct: 888 ISMTFADDAGEYTIVIRNKFGEASATVSLLEEADYEAYIKSQQEMMYQT 936 Score = 37.1 bits (82), Expect = 2.9 Identities = 64/286 (22%), Positives = 106/286 (37%), Gaps = 23/286 (8%) Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350 + P I S V G A F G+P+P W G + D+ + Sbjct: 1803 EAPKIFERIQSQTVAQGTDAHFRVRVVGKPDPECQWFRNGVQI-----ERTDRIYWYWPE 1857 Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410 D V L I D +DS +I+ AVN AG + L V + + I N Sbjct: 1858 DNVCELVIRDVTADDSA-SIMVKAVNIAGETSSHAFLLVQA--KQLISFIQNLQDVVAKE 1914 Query: 411 IKSMAVFPCTAICTPEPII--AWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTY 465 SMA F C T EP I W+ G + + + +D L + ++ SD+ Y Sbjct: 1915 RDSMATFECE---TSEPFIKVKWFKNGIEIHSGEKYRMHSDRKAHFLSVLAVEMSDADDY 1971 Query: 466 TCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWS 525 +C A + L+V+ + + F + + +P T + V+ + W Sbjct: 1972 SC-ALVEDESVKTTAKLIVEGAV---VEFIKELEDVEVPESFTGELECEVSPEDIEGKWY 2027 Query: 526 QNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRG---WVVIARRVH 568 + SS+ R L+ + ++ +G +VV +R H Sbjct: 2028 HGDVELSSNHKYVLASRRGRRILTIKDVNKDDQGEYSFVVDGKRTH 2073 Score = 36.3 bits (80), Expect = 5.1 Identities = 27/97 (27%), Positives = 47/97 (48%), Gaps = 7/97 (7%) Query: 724 AQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVV-NWLDVPANKSM 782 A++ +VP GPP N+E+ +N L W PE ITGY + + N + +M Sbjct: 7421 AKSKFEVP-GPPQNVEVTDVNRFGRTLTWEAPEYD-GGSPITGYVIELRNRASIKWEPTM 7478 Query: 783 VAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819 TT S ++T++ Y ++ A+ ++G+G Sbjct: 7479 ----TTGADELSAVLTDVVENEEYFFRVRAQNMVGVG 7511 Score = 35.9 bits (79), Expect = 6.7 Identities = 43/194 (22%), Positives = 79/194 (40%), Gaps = 16/194 (8%) Query: 142 WKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIAR--NAAGTRESAIATLK 197 W K+G + + + DG + L I D + +DAG Y C+ R N T + + + Sbjct: 5389 WMKDGSNIR-ESPKHKFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLIVEE 5447 Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA-----GGGNMPLGRVKVL 252 + ++ ++ T E+V G + C + + V+WRR G LG + + Sbjct: 5448 LPVR-FVKTLEEEVTVVKGQPLYLTCELNKE--RSVVWRRDGKIIKDKPGKFALGIIGL- 5503 Query: 253 DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARF 312 SL + + +D G Y+ E+S + S+ + + +V+ A F Sbjct: 5504 -SHSLTITDSDDSDAGTYTVTVEDSELSCSSCVKVVEVIRDWLVKPIRDQHVKPKGTATF 5562 Query: 313 TCTATGRPEPTMFW 326 TC + P + W Sbjct: 5563 TCDIV-KDTPNIKW 5575 >UniRef50_P20241 Cluster: Neuroglian precursor; n=17; Endopterygota|Rep: Neuroglian precursor - Drosophila melanogaster (Fruit fly) Length = 1302 Score = 154 bits (374), Expect = 1e-35 Identities = 173/633 (27%), Positives = 253/633 (39%), Gaps = 75/633 (11%) Query: 27 QPATLNCRA-GGSPSPAIRWY-----KGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80 +P L C A G PSP + W G + ++++ ++ P G L+F T SD Sbjct: 149 EPFMLKCAAPDGFPSPTVNWMIQESIDGSIKSINNSRMTLDPEGNLWFSNVTREDASSDF 208 Query: 81 GVYWCEATNSYGTA-RSRNATL----HVAVLREEFRLEP-----ESKQSA--QGDTVVLE 128 Y C AT+ + + + N L + V + + P +QS +G + L Sbjct: 209 -YYACSATSVFRSEYKIGNKVLLDVKQMGVSASQNKHPPVRQYVSRRQSLALRGKRMELF 267 Query: 129 CLPPRGSPEPNVYWKKNGQTLLF-DGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 C+ G+P P W K+GQ + + D ++ H G +LVI+ DAG Y C N G Sbjct: 268 CIYG-GTPLPQTVWSKDGQRIQWSDRITQGHY--GKSLVIRQTNFDDAGTYTCDVSNGVG 324 Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG--GGNMP 245 +S L ++ PY PE A V F+CR G P P + W + + P Sbjct: 325 NAQSFSIILNVNSVPYFTKEPEIATAAEDEEVVFECRAAGVPEPKISWIHNGKPIEQSTP 384 Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-DPPSINLSPNSVNV 304 R + + D ++R+ N++ D G Y C A NS+G V YL V +PP+I+ +P +V+ Sbjct: 385 NPR-RTVTDNTIRIINLVKGDTGNYGCNATNSLGYVYKDVYLNVQAEPPTISEAPAAVST 443 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 G C G P+P + W N ++ +Y+ A D L I D + Sbjct: 444 VDGRNVTIKCRVNGSPKPLVKWLRASN------WLTGGRYNVQANGD----LEIQDVTFS 493 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI-- 422 D+ C A N G G L V + R IT P N + A F C Sbjct: 494 DA-GKYTCYAQNKFGEIQADGSL-VVKEHTR----ITQEPQNYEVAAGQSATFRCNEAHD 547 Query: 423 CTPEPIIAWYFEGEAL-IQNHRRNV-TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480 T E I W+ +G+++ + R V TND +L + + DSG YTCVA +R + Sbjct: 548 DTLEIEIDWWKDGQSIDFEAQPRFVKTNDNSLTIAKTMELDSGEYTCVARTRLDEATARA 607 Query: 481 ALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQV 540 L+V PN P IT + W Q S IL Y + Sbjct: 608 NLIVQDV--PN-------------APKLTGITCQADKAEI--HWEQQGD-NRSPILHYTI 649 Query: 541 EVFSRETLSGNNTPRNSRGWVVIARRVHQT-HYVVKSLIPGITYMFIVRTENSHGLSGPS 599 + NT W +V T V + P Y F V N G S PS Sbjct: 650 QF---------NTSFTPASWDAAYEKVPNTDSSFVVQMSPWANYTFRVIAFNKIGASPPS 700 Query: 600 PVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILT 632 SDS T D V TE N +++ Sbjct: 701 AHSDSCTTQPDVPFKNPDNVVGQGTEPNNLVIS 733 Score = 123 bits (297), Expect = 3e-26 Identities = 124/479 (25%), Positives = 189/479 (39%), Gaps = 37/479 (7%) Query: 28 PATLNCRAGGSPSPAIRWYKGGVLVVSDTHRS-ILPAGGLFFLRATHGRVHSDAGVYWCE 86 P + C A G P P W K G + + +L G L T + D G Y C Sbjct: 54 PFIIECEADGQPEPEYSWIKNGKKFDWQAYDNRMLRQPGRGTLVITIPK-DEDRGHYQCF 112 Query: 87 ATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW---K 143 A+N +GTA S + + A L ++ ++ +G+ +L+C P G P P V W + Sbjct: 113 ASNEFGTATSNSVYVRKAELNAFKDEAAKTLEAVEGEPFMLKCAAPDGFPSPTVNWMIQE 172 Query: 144 KNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR---YQCIARNAAGTRESAIATLKIHI 200 ++ +SRM L GNL + + DA Y C A + + + + + Sbjct: 173 SIDGSIKSINNSRMTLDPEGNLWFSNVTREDASSDFYYACSATSVFRSEYKIGNKVLLDV 232 Query: 201 KPYLITGPED-------------VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247 K ++ ++ +A G + C GG PLP +W + G Sbjct: 233 KQMGVSASQNKHPPVRQYVSRRQSLALRGKRMELFCIYGGTPLPQTVWSKD-GQRIQWSD 291 Query: 248 RVKVLDDG-SLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSPNSVNVE 305 R+ G SL + D G Y+C+ N VG A S S L V P P Sbjct: 292 RITQGHYGKSLVIRQTNFDDAGTYTCDVSNGVGNAQSFSIILNVNSVPYFTKEPEIATAA 351 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365 F C A G PEP + W G P V D T+ IN K D Sbjct: 352 EDEEVVFECRAAGVPEPKISWIHNGK-----PIEQSTPNPRRTVTDN-TIRIIN-LVKGD 404 Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425 + N C+A N G + L V ++ PP I+ P+ + C +P Sbjct: 405 TGN-YGCNATNSLGYVYKDVYLNVQAE----PPTISEAPAAVSTVDGRNVTIKCRVNGSP 459 Query: 426 EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 +P++ W + R NV +G L ++D+ SD+G YTC A ++ G+ G+L+V Sbjct: 460 KPLVKW-LRASNWLTGGRYNVQANGDLEIQDVTFSDAGKYTCYAQNKFGEIQADGSLVV 517 Score = 102 bits (244), Expect = 7e-20 Identities = 78/288 (27%), Positives = 117/288 (40%), Gaps = 15/288 (5%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT--HRSILPAGGLFFL 69 PY ++P T A + CRA G P P I W G + T R + + + Sbjct: 339 PYFTKEPEIATAAEDEEVVFECRAAGVPEPKISWIHNGKPIEQSTPNPRRTVTDNTIRII 398 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 G D G Y C ATNS G ++ L+V P + + G V ++C Sbjct: 399 NLVKG----DTGNYGCNATNSLGYV-YKDVYLNVQAEPPTISEAPAAVSTVDGRNVTIKC 453 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189 GSP+P V W + L R ++ G+L IQD +DAG+Y C A+N G Sbjct: 454 -RVNGSPKPLVKWLRASNWLT---GGRYNVQANGDLEIQDVTFSDAGKYTCYAQNKFGEI 509 Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV---LWRRSAGGGNMPL 246 + A +L + + P++ G S TF+C D ++ W+ Sbjct: 510 Q-ADGSLVVKEHTRITQEPQNYEVAAGQSATFRCNEAHDDTLEIEIDWWKDGQSIDFEAQ 568 Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294 R +D SL + + D GEY+C A + +A L V D P+ Sbjct: 569 PRFVKTNDNSLTIAKTMELDSGEYTCVARTRLDEATARANLIVQDVPN 616 Score = 94.3 bits (224), Expect = 2e-17 Identities = 115/424 (27%), Positives = 171/424 (40%), Gaps = 47/424 (11%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDG-DSRMHLVDG-GNLVI 167 F++ ++K+S + ++EC G PEP W KNG+ + D+RM G G LVI Sbjct: 42 FKVAQQNKES--DNPFIIEC-EADGQPEPEYSWIKNGKKFDWQAYDNRMLRQPGRGTLVI 98 Query: 168 QDARQTDAGRYQCIARNAAGTRES-AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV- 225 + D G YQC A N GT S ++ K + + + + A G +C Sbjct: 99 TIPKDEDRGHYQCFASNEFGTATSNSVYVRKAELNAFKDEAAKTLEAVEGEPFMLKCAAP 158 Query: 226 GGDPLPDVLW--RRSAGGGNMPLGRVKV-LD-DGSLRLDNVILADEGE---YSCEA---- 274 G P P V W + S G + ++ LD +G+L NV D Y+C A Sbjct: 159 DGFPSPTVNWMIQESIDGSIKSINNSRMTLDPEGNLWFSNVTREDASSDFYYACSATSVF 218 Query: 275 --ENSVG--------AVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTM 324 E +G + S + P +S G C G P P Sbjct: 219 RSEYKIGNKVLLDVKQMGVSASQNKHPPVRQYVSRRQSLALRGKRMELFCIYGGTPLPQT 278 Query: 325 FWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR 384 WS +G R +++ Y + L I T+ +D+ T C N G++ Sbjct: 279 VWSKDGQRIQWSDRITQGHYGKS--------LVIRQTNFDDA-GTYTCDVSNGVGNA--- 326 Query: 385 GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ---N 441 ++ + + P T P T VF C A PEP I+W G+ + Q N Sbjct: 327 QSFSIILNVN-SVPYFTKEPEIATAAEDEEVVFECRAAGVPEPKISWIHNGKPIEQSTPN 385 Query: 442 HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVS 501 RR VT D T+ + +L K D+G Y C A++ G YV+ L P I AA VS Sbjct: 386 PRRTVT-DNTIRIINLVKGDTGNYGCNATNSLG-YVYKDVYLNVQAEPPTISEAPAA-VS 442 Query: 502 SLPG 505 ++ G Sbjct: 443 TVDG 446 Score = 76.6 bits (180), Expect = 4e-12 Identities = 49/177 (27%), Positives = 80/177 (45%), Gaps = 12/177 (6%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P I E P V+ + T+ CR GSP P ++W + + + ++ G L Sbjct: 430 EPPTISEAPAAVSTVDGRNVTIKCRVNGSPKPLVKWLRASNWLTGGRY-NVQANGDLEIQ 488 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL--EPESKQSAQGDTVVL 127 T SDAG Y C A N +G ++ + V++E R+ EP++ + A G + Sbjct: 489 DVT----FSDAGKYTCYAQNKFGEIQADGS----LVVKEHTRITQEPQNYEVAAGQSATF 540 Query: 128 ECLPPRGSP-EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183 C E + W K+GQ++ F+ R + +L I + D+G Y C+AR Sbjct: 541 RCNEAHDDTLEIEIDWWKDGQSIDFEAQPRFVKTNDNSLTIAKTMELDSGEYTCVAR 597 >UniRef50_Q0E9K8 Cluster: CG17800-PAN; n=84; Endopterygota|Rep: CG17800-PAN - Drosophila melanogaster (Fruit fly) Length = 2037 Score = 153 bits (371), Expect = 3e-35 Identities = 203/849 (23%), Positives = 332/849 (39%), Gaps = 98/849 (11%) Query: 12 PYIIEQPLDVTVARHQPAT-LNCRAGGSPSPAIRWYKGGVLVVSDTHRSI---LPAGGLF 67 P +I Q P+ L C AGG+P+P I W G + ++ + + G Sbjct: 429 PPVIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQYVTVNGDV 488 Query: 68 FLRATHGRVHS-DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126 VH+ D G+Y C A + G A +A L+V L + + E K G+T++ Sbjct: 489 VSYLNITSVHANDGGLYKCIAKSKVGVAE-HSAKLNVYGL--PYIRQMEKKAIVAGETLI 545 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA-RQTDAGRYQCIARNA 185 + C P G P ++ W+++ + L + + + G L+I++ R +D Y C+A+N Sbjct: 546 VTC-PVAGYPIDSIVWERDNRALPIN--RKQKVFPNGTLIIENVERNSDQATYTCVAKNQ 602 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGG 242 G +++ + P ++ P D +T V+ C V P L+ +A Sbjct: 603 EGYSARGSLEVQVMVPPQVV--PFDFGEETINMNDMVSATCTVNKGDTPLELYWTTAPDP 660 Query: 243 NMPLGRVKVLDD----------GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292 +GR+ D L +++V Y+C A N+ G + + L V P Sbjct: 661 TTGVGRLMSNDGILITKTTQRISMLSIESVHARHRANYTCVARNAAGVIYHTAELRVNVP 720 Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352 P L P G+ A+ C A G P+P + W T PG +D + + Sbjct: 721 PRWILEPTDKAFAQGSDAKVECKADGFPKPQVTWKKAVGDT---PGEYKDLKKSDNIRVE 777 Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412 L +++ K + +C A+N GS G V + PP T NQT Sbjct: 778 EGTLHVDNIQKT-NEGYYLCEAINGIGS----GLSAVIMISVQAPPEFTEKLRNQTARRG 832 Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNH------RRNVTNDG---TLVLKDLDKSDSG 463 AV C A I W L + R + + G +L +K ++SDS Sbjct: 833 EPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGVMSSLSIKRTERSDSA 892 Query: 464 TYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLS 523 +TCVA++ G D+ IN V +P P + + SV LS Sbjct: 893 LFTCVATNAFGS--------DDASIN--------MIVQEVPEMPYALKVLDKSGRSVQLS 936 Query: 524 WSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITY 583 W+Q G+S + Y +E F R S + R V++ H T V+ L P TY Sbjct: 937 WAQPYD-GNSPLDRYIIE-FKRSRASWSEIDR-----VIVPG--HTTEAQVQKLSPATTY 987 Query: 584 MFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATP 643 + EN+ G S S +T + + S + +N I+ P Sbjct: 988 NIRIVAENAIGTSQSSEAVTIITAEE-----------APSGKPQN----------IKVEP 1026 Query: 644 IDSKTIKLMWEILNFYYLEGLFI-YF--RPLDNITIEYEMKT---ILHSNDVSGFEITSL 697 ++ T+++ W+ G + Y+ L N Y +T I E+ +L Sbjct: 1027 VNQTTMRVTWKPPPRTEWNGEILGYYVGYKLSNTNSSYVFETINFITEEGKEHNLELQNL 1086 Query: 698 RKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPEL 757 R YT+Y + F K G S T + P PP + L + T+ + W P L Sbjct: 1087 RVYTQYSVVIQAFNKIGAGPLSEEEKQFTAEGTPSQPPSDTACTTLTSQTIRVGWVSPPL 1146 Query: 758 QLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817 + NG+I Y VV D +++ T T ++ L +Y++Q+ A T G Sbjct: 1147 ESANGVIKTYKVVYAPSDEWYDETKRHYKKTASSDT--VLHGLKKYTNYTMQVLATTAGG 1204 Query: 818 LGPFSQKVY 826 G S ++ Sbjct: 1205 DGVRSVPIH 1213 Score = 124 bits (299), Expect = 1e-26 Identities = 148/585 (25%), Positives = 235/585 (40%), Gaps = 68/585 (11%) Query: 10 EAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTH--RSILPAGGL 66 + P +++P + + + A + C+A G+P P I W + V D R I G L Sbjct: 37 KGPVFLKEPTNRIDFSNSTGAEIECKASGNPMPEIIWIRSDGTAVGDVPGLRQISSDGKL 96 Query: 67 FF--LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV-AVLREEFRLEPESKQSAQGD 123 F RA R A VY C A N +G+ SR+ +HV AV+ + + E ++ +G+ Sbjct: 97 VFPPFRAEDYRQEVHAQVYACLARNQFGSIISRD--VHVRAVVNQFYEAEIMTEYVIRGN 154 Query: 124 TVVLECLPPRGSPE---PNVYWKKNGQTLLFDG--DSRMHLVDGGNLVIQDARQTDAGR- 177 VL+C P + + G L F D + ++ G L I++ D + Sbjct: 155 AAVLKCSIPSFVADFVRVESWIDDEGNVLSFSDNYDGKYLVLPSGELHIREVGPEDGYKS 214 Query: 178 YQCIARN--AAGTRESAIATLKIHIKPYLITGPE---------DVVAQTGSSVTFQCRVG 226 YQC ++ TR SA + +P P D + Q + F C Sbjct: 215 YQCRTKHRLTGETRLSATKGRLVITEPVGSVAPRVNKKDGFSHDSIRQDRTIAIF-CPAQ 273 Query: 227 GDPLPDVLWRRSAGGGNMPLG-----RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281 P+P W + G RVK + G+L + + ++ D G+Y C NSVG Sbjct: 274 AYPVPFYRWYKFIEGTTRKQAVVLNDRVKQVS-GTLIIKDAVVEDSGKYLCVVNNSVGGE 332 Query: 282 SASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341 S LTV P S + P + V+ G A FTC TG P T+ W +G Sbjct: 333 SVETVLTVTAPLSAKIDPPTQTVDFGRPAVFTCQYTGNPIKTVSWMKDGK---------- 382 Query: 342 DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401 A+ VL I K D + C N S+ +L + D PP+I Sbjct: 383 ------AIGHSEPVLRIESVKKED-KGMYQCFVRNDQESAEASAELKLGGRFD--PPVIR 433 Query: 402 NGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR----RNVTNDGTLV---- 453 +T+ C A P P I+W +G+ + N R + VT +G +V Sbjct: 434 QAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQYVTVNGDVVSYLN 493 Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITH 513 + + +D G Y C+A S+ G S L V + + R + ++ T +T Sbjct: 494 ITSVHANDGGLYKCIAKSKVGVAEHSAKLNV-----YGLPYIRQMEKKAIVAGETLIVTC 548 Query: 514 NVTDTSV-TLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNS 557 V + ++ W ++N+ + + + +VF TL N RNS Sbjct: 549 PVAGYPIDSIVWERDNR---ALPINRKQKVFPNGTLIIENVERNS 590 Score = 111 bits (266), Expect = 1e-22 Identities = 108/414 (26%), Positives = 169/414 (40%), Gaps = 29/414 (7%) Query: 121 QGDTVVLECLPPRGSPEPNVYWKK--NGQTL--LFDGDSRMHLVDGGNLVIQDARQTDAG 176 Q T+ + C P + P P W K G T + R+ V G L+I+DA D+G Sbjct: 262 QDRTIAIFC-PAQAYPVPFYRWYKFIEGTTRKQAVVLNDRVKQVSG-TLIIKDAVVEDSG 319 Query: 177 RYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 +Y C+ N+ G ES L + P G F C+ G+P+ V W Sbjct: 320 KYLCVVNNSVGG-ESVETVLTVTAPLSAKIDPPTQTVDFGRPAVFTCQYTGNPIKTVSWM 378 Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDPP 293 + G+ + LR+++V D+G Y C N + AS L + +DPP Sbjct: 379 KD--------GKAIGHSEPVLRIESVKKEDKGMYQCFVRNDQESAEASAELKLGGRFDPP 430 Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353 I + +E G C A G P P + W ++G + +Y T D V Sbjct: 431 VIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQY-VTVNGDVV 489 Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413 + L I ND C A + G + KL V P I + ++ Sbjct: 490 SYLNITSVHANDG-GLYKCIAKSKVGVAEHSAKLNVYG-----LPYIRQMEKKAIVAGET 543 Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDK-SDSGTYTCVASSR 472 + V C P I W + AL N ++ V +GTL+++++++ SD TYTCVA ++ Sbjct: 544 LIV-TCPVAGYPIDSIVWERDNRALPINRKQKVFPNGTLIIENVERNSDQATYTCVAKNQ 602 Query: 473 HGKYVWSGALLVDSPINPN-IHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWS 525 G Y G+L V + P + F + ++ + T N DT + L W+ Sbjct: 603 EG-YSARGSLEVQVMVPPQVVPFDFGEETINMNDMVSATCTVNKGDTPLELYWT 655 Score = 60.1 bits (139), Expect = 4e-07 Identities = 32/104 (30%), Positives = 50/104 (48%) Query: 384 RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR 443 + K V D+ P I + T K A PC A+ P+P I W +G N R Sbjct: 1305 QSKSIVAMPSDQVPAKIASFDDTFTATFKEDAKMPCLAVGAPQPEITWKIKGVEFSANDR 1364 Query: 444 RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 V DG+L++K +++ D+G Y+C A + K + L+V +P Sbjct: 1365 MRVLPDGSLLIKSVNRQDAGDYSCHAENSIAKDSITHKLIVLAP 1408 Score = 52.4 bits (120), Expect = 7e-05 Identities = 34/108 (31%), Positives = 48/108 (44%), Gaps = 2/108 (1%) Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 G + +I + P I +D T C G P P++ W+ G Sbjct: 1303 GQQSKSIVAMPSDQVPAKIASFDDTFTATFKEDAKMPCLAVGAPQPEITWKIK-GVEFSA 1361 Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293 R++VL DGSL + +V D G+YSC AENS+ S + L V PP Sbjct: 1362 NDRMRVLPDGSLLIKSVNRQDAGDYSCHAENSIAKDSITHKLIVLAPP 1409 Score = 49.6 bits (113), Expect = 5e-04 Identities = 43/186 (23%), Positives = 75/186 (40%), Gaps = 8/186 (4%) Query: 642 TPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFE--ITSLRK 699 T + S+TI++ W G+ ++ + + E+ +T H + + + L+K Sbjct: 1130 TTLTSQTIRVGWVSPPLESANGVIKTYKVVYAPSDEWYDETKRHYKKTASSDTVLHGLKK 1189 Query: 700 YTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQL 759 YT Y ++ +G S QT DVP+ P +++ ++ + + W PP Sbjct: 1190 YTNYTMQVLATTAGGDGVRSVPIHCQTEPDVPEA-PTDVKALVMGNAAILVSWRPP--AQ 1246 Query: 760 QNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819 NGIIT Y V + ++ H S T L Y + A T IG G Sbjct: 1247 PNGIITQYTV---YSKAEGAETETKTQKVPHYQMSFEATELEKNKPYEFWVTASTTIGEG 1303 Query: 820 PFSQKV 825 S+ + Sbjct: 1304 QQSKSI 1309 Score = 46.8 bits (106), Expect = 0.004 Identities = 45/183 (24%), Positives = 77/183 (42%), Gaps = 12/183 (6%) Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193 G+P+P + WK G + F + RM ++ G+L+I+ + DAG Y C A N+ ++S Sbjct: 1344 GAPQPEITWKIKG--VEFSANDRMRVLPDGSLLIKSVNRQDAGDYSCHAENSI-AKDSIT 1400 Query: 194 ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV-GGD--PLPDVLWRRSAGGGNMPLGRVK 250 L + P + + A T ++T + + GD PL G V Sbjct: 1401 HKLIVLAPPQ--SPHVTLSATTTDALTVKLKPHEGDTAPLHGYTLHYKPEFGEWETSEVS 1458 Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYL---TVYDPPSINLSPNSVNVESG 307 V D ++ ++ + N++GA AS L T P + P + V S Sbjct: 1459 V-DSQKHNIEGLLCGSRYQVYATGFNNIGAGEASDILNTRTKGQKPKLPEKPRFIEVSSN 1517 Query: 308 NVA 310 +V+ Sbjct: 1518 SVS 1520 Score = 37.9 bits (84), Expect = 1.7 Identities = 23/69 (33%), Positives = 29/69 (42%), Gaps = 4/69 (5%) Query: 22 TVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAG 81 T + A + C A G+P P I W GV ++ +LP G L DAG Sbjct: 1329 TATFKEDAKMPCLAVGAPQPEITWKIKGVEFSANDRMRVLPDGSLLIKSVN----RQDAG 1384 Query: 82 VYWCEATNS 90 Y C A NS Sbjct: 1385 DYSCHAENS 1393 >UniRef50_A5X6X5 Cluster: Titin a; n=10; Euteleostomi|Rep: Titin a - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 32757 Score = 152 bits (369), Expect = 5e-35 Identities = 137/491 (27%), Positives = 201/491 (40%), Gaps = 24/491 (4%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 +T E I EQ V+V PATL CR G+ +W K G + S I + Sbjct: 5637 LTVKEPANITEQAKSVSVTVRDPATLECRYSGTKVLKAKWLKDGNELTSGRKYKIQSSDT 5696 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNA-TLHVAVLREEFRLEPESKQSAQGDT 124 L+ SDAG Y E +N G + T+ +++ F + + +S +G Sbjct: 5697 SSILKILSAE-KSDAGEYTFEVSNDAGRSSCEAVVTVLDQIIKPSFTRKLKETESIKGSF 5755 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSR-MHLVDGGNLVIQDARQTDAGRYQCIAR 183 LECL GS NV W K + + D + + + +L I +D+G Y CIA+ Sbjct: 5756 TQLECLVS-GSLPINVTWFKENKEIEADEKHKCIFFENAASLEISRLDSSDSGNYTCIAK 5814 Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG--G 241 N AG+ + + TLK+ P +I PE GS V F + G P + W + Sbjct: 5815 NQAGSDQCS-GTLKVKEPPSIIEKPESQDVIPGSKVQFNVLLSGTPPLTINWFKDTKEVS 5873 Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301 + K S+ L +D G+Y CE N VG+ S L V +PP P Sbjct: 5874 SGIDCSVQKNDTSSSIELFFAKPSDSGQYVCEVSNDVGSDSCQATLFVKEPPKFTRKPEK 5933 Query: 302 VN-VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360 + V+ + F C TG PE +W +GN I P DKY T V D + L I Sbjct: 5934 ITVVKPSQLVVFECQITGTPEIDTYWFKDGND--ISPS---DKYKMTFV-DSLARLEIIS 5987 Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420 +D DS C A N AGS L V + PP++ S + S A F C Sbjct: 5988 SDIKDS-GVYYCEARNEAGSESCSMDLRV-----KEPPVLVKPLSPLEVVNGSNAYFECL 6041 Query: 421 AICTPEPIIAWYFEGEALIQNHRRNV--TNDG--TLVLKDLDKSDSGTYTCVASSRHGKY 476 T + W + + + + + + ND TL ++ D D G Y C+ ++ G Sbjct: 6042 VKGTAPFEVTWEKDSKDIKSSLKHVILQKNDSIITLDVQKCDALDVGEYQCIVANEVGSC 6101 Query: 477 VWSGALLVDSP 487 L + P Sbjct: 6102 SSQSTLSIKEP 6112 Score = 139 bits (336), Expect = 5e-31 Identities = 122/487 (25%), Positives = 203/487 (41%), Gaps = 30/487 (6%) Query: 10 EAPYIIEQPLDVTVAR-HQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68 E P +P +TV + Q C+ G+P W+K G + + L Sbjct: 5923 EPPKFTRKPEKITVVKPSQLVVFECQITGTPEIDTYWFKDGNDISPSDKYKMTFVDSLAR 5982 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK-QSAQGDTVVL 127 L + D+GVY+CEA N G S + ++ + V ++P S + G Sbjct: 5983 LEIISSDI-KDSGVYYCEARNEAG---SESCSMDLRVKEPPVLVKPLSPLEVVNGSNAYF 6038 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV--DGGNLVIQDARQTDA---GRYQCIA 182 ECL +G+ V W+K+ + + S H++ +++ D ++ DA G YQCI Sbjct: 6039 ECLV-KGTAPFEVTWEKDSKDIK---SSLKHVILQKNDSIITLDVQKCDALDVGEYQCIV 6094 Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG- 241 N G+ S +TL I P + E+VV G V F+C V G P + W++ Sbjct: 6095 ANEVGSCSSQ-STLSIKEPPSFVERIENVVTVLGKMVEFKCVVRGSPPLSIQWQKDESWI 6153 Query: 242 -GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300 + + R + +L + G+Y+C+A N G L V +PP I P Sbjct: 6154 LEDPSIQRTFENNVATLTIPVCESIHSGKYTCQAMNEAGQEKCFSTLVVQEPPQIIEKPE 6213 Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360 +NV +G+ F C +G PE + WS +G I + H+ + + V+ L + Sbjct: 6214 VINVTAGDPVSFECKVSGTPELKVKWSKDGKEVI------PSRQHSLSYINNVSQLKLQS 6267 Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420 D + T V N+ + + L V + PP I + + K++ + C Sbjct: 6268 VQLED-KGTYVFEVSNHISACQCKVTLNVL-EQIIPPSFIKPLMEMEEIIGKNVQI-GCK 6324 Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKD---LDKSDSGTYTCVASSRHGKYV 477 + + W +G L + + D V D L+K+D+GTYTC +++ G Sbjct: 6325 ISGSLPITVEWEKDGTKLSGRTKHKILQDENSVSLDIECLEKADTGTYTCKLANKAGSCE 6384 Query: 478 WSGALLV 484 SG L V Sbjct: 6385 CSGTLRV 6391 Score = 138 bits (333), Expect = 1e-30 Identities = 129/531 (24%), Positives = 218/531 (41%), Gaps = 26/531 (4%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P + P V T GS ++W++G +VS I G L Sbjct: 6935 EPPSFVTTPQPVEALPGTTVTFTATVQGSTPMKLKWFRGSKEIVSGRSCEIALRGDTAIL 6994 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDTVVLE 128 H S AG Y C+ N G N +++ V ++ S + G +++LE Sbjct: 6995 EL-HNIDKSHAGEYTCQIINDAG---KENCPVNLFVKEAAHFVKKLKNLSVEMGKSLILE 7050 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAG 187 C GSP+ V W K+GQ + + + ++ ++ + AG+Y C N AG Sbjct: 7051 CTYA-GSPKILVKWHKDGQEIYSSYKYNITTTESSCILECLNSDKEAAGKYTCEVSNDAG 7109 Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPL 246 + A + I P+ I E + G +V +C++GG P + W ++ G + P Sbjct: 7110 -HDICEAAVSILEPPFFIESLEPMEVTAGDAVCLKCQIGGTPEIKISWFKADGKVRSSPT 7168 Query: 247 GRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLSPNSV 302 +++ L+L V +D GEY+C+AENS+G+ ++S +LTV D PPS S+ Sbjct: 7169 CKMEFFKGIACLKLAKVAKSDIGEYTCKAENSIGSATSSCHLTVQDVKTPPSFPKKITSI 7228 Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362 G +F C G + W +G + D + + D VL I + Sbjct: 7229 MQIEGQPVQFECRVAGSSPMEVSWLKDGE------ALRSDSEYTMSFDDNSAVLNIAKGE 7282 Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422 S C A N GS+ R KLT+ + R PP+ + + C Sbjct: 7283 MRHS-GEYTCVATNSVGSASCRAKLTL--QEPRYPPVFDKKLVPVDVSVGDTVELECHMT 7339 Query: 423 CTPEPIIAWYFEGEALIQ--NHRRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479 + + W + + + N++ + V N L + DK+DSG Y+C AS+ GK S Sbjct: 7340 GSMPIKVTWSKDHKDIRTGGNYKISCVENTPHLTILKADKADSGRYSCHASNDVGKDSCS 7399 Query: 480 GALLV-DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529 + V + I P+ + + + G K +T++W ++ + Sbjct: 7400 TEVSVKERKIPPSFTKKPSTTIEDIEGKVVKIEGRVAGSQPLTVNWYKDGR 7450 Score = 122 bits (293), Expect = 8e-26 Identities = 134/530 (25%), Positives = 213/530 (40%), Gaps = 29/530 (5%) Query: 10 EAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68 E P +++ P V +P L C+ G+ I WYK ++SD + Sbjct: 6465 EPPEFVQKLPAAKVVKMGEPLQLECKVTGTAPLRISWYKNDA-ILSDGGNLRMTFDNSVA 6523 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128 + D GVY CEA N GT +S + L + ++L P + +G L Sbjct: 6524 VLEISTSSFDDNGVYTCEAQNDAGT-KSCSTALTIKEPPSFYKL-PTPVEGLKGKDASLN 6581 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAA 186 C +GS + W K+ + L + + +G L I +DAG Y+C A N Sbjct: 6582 C-ELKGSAPFEITWFKDKKQLK-ESRKYKFVSEGCSATLHILGLEASDAGEYECKATNNV 6639 Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 G+ + ++K+ P + + A +G V V G V W + Sbjct: 6640 GS-DLCQGSVKLREPPAFVKKLSNTTAISGEEVVLLTTVKGSQPMTVSWVQDKDHILRDG 6698 Query: 247 GRVKVLDDGSLRLDNVILADE---GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303 K+ + + V AD G+Y+C+ +N G + LTV +P +I +S++ Sbjct: 6699 ENRKITFENNEVTLKVFKADSTTAGKYTCQLKNDAGVAECTANLTVLEPAAIVDKTDSIS 6758 Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363 V +G A CT +G PE W +G +S K + ++ L + T++ Sbjct: 6759 VTAGEAAALECTVSGTPELKPKWFKDGVE------LSSGKKYKITFSKMISSLKLLSTER 6812 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423 +D+ S N GS +LTV D PP Q++ KSM + C A Sbjct: 6813 SDT-GEYTFSIKNEVGSDSCAMQLTVL-DKIVPPLFSRKLKDTQSIVGKSMEL-DCKASG 6869 Query: 424 TPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480 + I+W+ ++ +T N TL + L SDSGTY C A + G S Sbjct: 6870 SAPLTISWFHNEVEIMSGPNYEITFTENTCTLKVPTLKLSDSGTYKCKAVNSAGAAETSA 6929 Query: 481 ALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVT-DTSVTLSWSQNNK 529 +L+V P P+ V +LPG T T V T + L W + +K Sbjct: 6930 SLVVKEP--PSF-VTTPQPVEALPG-TTVTFTATVQGSTPMKLKWFRGSK 6975 Score = 120 bits (289), Expect = 2e-25 Identities = 137/535 (25%), Positives = 217/535 (40%), Gaps = 35/535 (6%) Query: 13 YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRAT 72 ++++ L V ATL C+ GSP +IRWYK + SD + + LR + Sbjct: 5365 FVMKLDLTKLVLNGSLATLECKVAGSPEISIRWYKNETEIGSDDKYQMAFTDSVATLRIS 5424 Query: 73 HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP 132 V D+G Y C+A++ G+ R + L EF ESK+ +G VVLE Sbjct: 5425 SCCVE-DSGDYICQASSDAGSDRC--SCLVTVKEPPEFVKPFESKEIVKGTDVVLEGTVS 5481 Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLV----DGGNLVIQDARQTDAGRYQCIARNAAG- 187 +P +K + Q + R H++ D L I DAG+YQC N G Sbjct: 5482 GSAPFEISCFKDSKQIR----NDRRHIISLTKDVAALQILKFEPGDAGKYQCTVGNEVGQ 5537 Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247 T + T+K P + ++ V+ QC + G + W + Sbjct: 5538 TSCDFLVTMKE--PPSFVQKMDNTNVLLAKDVSLQCVLKGSMPMTISWMKD-DHEIKESE 5594 Query: 248 RVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304 V++ + + + +V L G+Y+C A+N G+ + LTV +P +I SV+V Sbjct: 5595 HVQISFENQTAVIYISSVQLKHGGKYTCHAQNEAGSQKCTAVLTVKEPANITEQAKSVSV 5654 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 + A C +G W +GN S KY + D ++L I +K+ Sbjct: 5655 TVRDPATLECRYSGTKVLKAKWLKDGNEL-----TSGRKYKIQS-SDTSSILKILSAEKS 5708 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK-SMAVFPCTAIC 423 D+ N AG S +TV D P T +T IK S C Sbjct: 5709 DA-GEYTFEVSNDAGRSSCEAVVTVL--DQIIKPSFTR-KLKETESIKGSFTQLECLVSG 5764 Query: 424 TPEPIIAWYFEGEALIQNHRRN---VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480 + + W+ E + + + + N +L + LD SDSG YTC+A ++ G SG Sbjct: 5765 SLPINVTWFKENKEIEADEKHKCIFFENAASLEISRLDSSDSGNYTCIAKNQAGSDQCSG 5824 Query: 481 ALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSI 535 L V P P+I + +PG + +T++W ++ K SS I Sbjct: 5825 TLKVKEP--PSI-IEKPESQDVIPGSKVQFNVLLSGTPPLTINWFKDTKEVSSGI 5876 Score = 119 bits (287), Expect = 4e-25 Identities = 124/482 (25%), Positives = 193/482 (40%), Gaps = 31/482 (6%) Query: 17 QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV 76 Q L+V V A C +P +W+K G + I+ L V Sbjct: 4622 QNLEVNVG--SSAKFECEIEEAPGVTFKWFKSGTELRHSEKCRIISRHHTSSLEIFSPAV 4679 Query: 77 HSDAGVYWCEATNSYGTARSRNATLHVAVL-REEFRLEPESKQSAQGDTVVLECLPPRGS 135 +D+G Y C+A+N +G + S +A L V L EF +P+S G +C+ GS Sbjct: 4680 -ADSGEYTCKASNRHG-SDSCSAKLTVTELFPPEFVSKPDSMTLFVGKQAKFQCV-ISGS 4736 Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAI 193 NV W K+ + D D D L I + + +D G Y C A N+ GT + Sbjct: 4737 EPMNVVWHKDNIAISLD-DHYKESSDKNRYFLEILNLQHSDQGTYLCKASNSVGT-ATCC 4794 Query: 194 ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD 253 L++ KP + E G+ + +C+V D ++W R + + + Sbjct: 4795 TELRVVDKPSFVKSFESTTVAVGNPLRLECQVDEDTGVSIIWMRDGKKLHTTMDCKLAFE 4854 Query: 254 D--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNVESGNV 309 + L + L D G Y+C A N G+ S S +TV +PP L P + + G Sbjct: 4855 EKIACLDIQKSKLKDTGTYTCTAANEAGSSSCSSSVTVQEPPVFVKRLEP-KILWKQGMS 4913 Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369 +R +CT G PE + W + P S +K+ T + T L I D ++DS N Sbjct: 4914 SRLSCTVKGSPELHVTWFLNDK-----PLNSSEKHKITFKTNQAT-LEIIDLSESDSGN- 4966 Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429 C +N AG ++TV + PP + A C T I Sbjct: 4967 YTCEVMNEAGCESCSSQVTV-----KEPPAFKKELRLVEVVKGCTAHLECEMTGTAPFEI 5021 Query: 430 AWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSG-ALLVD 485 W+ + + + + N+ + T L +K + +D G Y C S+ GK A L D Sbjct: 5022 TWFKDKNPVSSDTKYNIVSKETAAYLEIKTFESADVGDYQCCISNDVGKITTKAVAKLKD 5081 Query: 486 SP 487 P Sbjct: 5082 PP 5083 Score = 119 bits (287), Expect = 4e-25 Identities = 128/483 (26%), Positives = 186/483 (38%), Gaps = 37/483 (7%) Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86 QP CR GS + W K G + SD+ ++ L G + +G Y C Sbjct: 7234 QPVQFECRVAGSSPMEVSWLKDGEALRSDSEYTMSFDDNSAVLNIAKGEMRH-SGEYTCV 7292 Query: 87 ATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145 ATNS G+A R TL F + + GDTV LEC GS V W K+ Sbjct: 7293 ATNSVGSASCRAKLTLQEPRYPPVFDKKLVPVDVSVGDTVELEC-HMTGSMPIKVTWSKD 7351 Query: 146 GQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAG--TRESAIATLKIHIKP 202 + + G+ ++ V+ +L I A + D+GRY C A N G + + ++ + I P Sbjct: 7352 HKDIRTGGNYKISCVENTPHLTILKADKADSGRYSCHASNDVGKDSCSTEVSVKERKIPP 7411 Query: 203 YLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLR--- 258 P + G V + RV G V W + G V SL Sbjct: 7412 SFTKKPSTTIEDIEGKVVKIEGRVAGSQPLTVNWYKD-GREIFTSDFYDVTFKSSLAVLC 7470 Query: 259 LDNVILADEGEYSCEAENSVGAVS--ASGYLTVYD-PPSINLSPNSVNVESGNVARFTCT 315 + L+D G Y C+A N G S S ++T PPS +L V V G +C Sbjct: 7471 IKKSQLSDSGTYVCKATNEAGTASFEVSVHITAQKVPPSFDLPLKPVTVNEGETLTLSCH 7530 Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375 G P + W + +S DG L + K DS + + C A Sbjct: 7531 VRGSPPLKIQWMKDRRE------LSSSANTKITFVDGTATLEMTRVSKTDSGDYL-CKAT 7583 Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNG--------PSNQTLPIKSMAVFPCTAICTPEP 427 N AG+ G PP + P + + K A F P P Sbjct: 7584 NEAGNK--PGAPAPAQAAPSPPQEVKKFDNLFFIEVPKSVHIVEKGTATFIAKVGGDPIP 7641 Query: 428 IIAWYFEGEALIQNHRRNVT-----NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482 + W +G+ H ++ + + +K++ KSDSG Y CVAS++HG+ S L Sbjct: 7642 NVKW-MKGKWRQMTHGGRISIEQKGQEAKMEIKEVTKSDSGQYRCVASNKHGEIECSTDL 7700 Query: 483 LVD 485 VD Sbjct: 7701 NVD 7703 Score = 119 bits (286), Expect = 6e-25 Identities = 122/493 (24%), Positives = 198/493 (40%), Gaps = 31/493 (6%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 VT P + +P +T+ + A C GS + W+K + + D H Sbjct: 4704 VTELFPPEFVSKPDSMTLFVGKQAKFQCVISGSEPMNVVWHKDNIAISLDDHYKESSDKN 4763 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 +FL + + HSD G Y C+A+NS GTA T V + F ES A G+ + Sbjct: 4764 RYFLEILNLQ-HSDQGTYLCKASNSVGTATC--CTELRVVDKPSFVKSFESTTVAVGNPL 4820 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARN 184 LEC + ++ W ++G+ L D ++ + L IQ ++ D G Y C A N Sbjct: 4821 RLECQVDEDT-GVSIIWMRDGKKLHTTMDCKLAFEEKIACLDIQKSKLKDTGTYTCTAAN 4879 Query: 185 AAGTRESAIATLKIHIKPYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 AG+ S +++ + P + E ++ + G S C V G P V W + N Sbjct: 4880 EAGS-SSCSSSVTVQEPPVFVKRLEPKILWKQGMSSRLSCTVKGSPELHVTWFLNDKPLN 4938 Query: 244 MPLGRVKV---LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300 + K+ + +L + ++ +D G Y+CE N G S S +TV +PP+ Sbjct: 4939 SS-EKHKITFKTNQATLEIIDLSESDSGNYTCEVMNEAGCESCSSQVTVKEPPAFKKELR 4997 Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360 V V G A C TG + W + N P S KY+ + + L I Sbjct: 4998 LVEVVKGCTAHLECEMTGTAPFEITWFKDKN-----PVSSDTKYNIVSK-ETAAYLEIKT 5051 Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD-RPPPIITNGPSNQTLPIKSMAVFPC 419 + D + C + + GK+T + + PP N T + S Sbjct: 5052 FESADVGDYQCCISNDV-------GKITTKAVAKLKDPPSFVKKVENTTAVLGSAVKLQG 5104 Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVT-----NDGTLVLKDLDKSDSGTYTCVASSRHG 474 T I PI +F+ ++++ N+T N L + ++ + G YTC A + G Sbjct: 5105 T-IKGSAPITVQWFKDTEIVRDDDPNITTTFENNIAVLAISNVAINHGGKYTCQAENEAG 5163 Query: 475 KYVWSGALLVDSP 487 K + V P Sbjct: 5164 KQKCEATVTVQEP 5176 Score = 119 bits (286), Expect = 6e-25 Identities = 128/485 (26%), Positives = 198/485 (40%), Gaps = 37/485 (7%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 +T E P + P V + + A+LNC GS I W+K + + G Sbjct: 6555 LTIKEPPSFYKLPTPVEGLKGKDASLNCELKGSAPFEITWFKDKKQLKESRKYKFVSEGC 6614 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGD 123 L G SDAG Y C+ATN+ G+ + + LRE F + + + G+ Sbjct: 6615 SATLHIL-GLEASDAGEYECKATNNVGSDLCQGS----VKLREPPAFVKKLSNTTAISGE 6669 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ--DARQTDAGRYQCI 181 VVL +GS V W ++ +L DG++R + + ++ A T AG+Y C Sbjct: 6670 EVVL-LTTVKGSQPMTVSWVQDKDHILRDGENRKITFENNEVTLKVFKADSTTAGKYTCQ 6728 Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRS-- 238 +N AG E A L + ++P I D ++ T G + +C V G P W + Sbjct: 6729 LKNDAGVAE-CTANLTV-LEPAAIVDKTDSISVTAGEAAALECTVSGTPELKPKWFKDGV 6786 Query: 239 --AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PP 293 + G + K++ SL+L + +D GEY+ +N VG+ S + LTV D PP Sbjct: 6787 ELSSGKKYKITFSKMI--SSLKLLSTERSDTGEYTFSIKNEVGSDSCAMQLTVLDKIVPP 6844 Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353 + G C A+G T+ W N I MS Y T + Sbjct: 6845 LFSRKLKDTQSIVGKSMELDCKASGSAPLTISWF--HNEVEI---MSGPNYEITFT-ENT 6898 Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413 L + +DS T C AVN AG++ L V PP +T + LP + Sbjct: 6899 CTLKVPTLKLSDS-GTYKCKAVNSAGAAETSASLVV----KEPPSFVTTPQPVEALP-GT 6952 Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVAS 470 F T + + W+ + ++ + G L L ++DKS +G YTC Sbjct: 6953 TVTFTATVQGSTPMKLKWFRGSKEIVSGRSCEIALRGDTAILELHNIDKSHAGEYTCQII 7012 Query: 471 SRHGK 475 + GK Sbjct: 7013 NDAGK 7017 Score = 116 bits (279), Expect = 4e-24 Identities = 105/415 (25%), Positives = 164/415 (39%), Gaps = 21/415 (5%) Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140 G Y CEA G + + + + FR ++ + G + EC +P Sbjct: 4588 GEYTCEAVGEAGKTSTSSHLTVIPRVPPVFRQRIQNLEVNVGSSAKFEC-EIEEAPGVTF 4646 Query: 141 YWKKNGQTLLFDGDSRM-HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE-SAIATLKI 198 W K+G L R+ +L I D+G Y C A N G+ SA T+ Sbjct: 4647 KWFKSGTELRHSEKCRIISRHHTSSLEIFSPAVADSGEYTCKASNRHGSDSCSAKLTVTE 4706 Query: 199 HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLR 258 P ++ P+ + G FQC + G +V+W + ++ + D Sbjct: 4707 LFPPEFVSKPDSMTLFVGKQAKFQCVISGSEPMNVVWHKDNIAISLDDHYKESSDKNRYF 4766 Query: 259 LD--NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316 L+ N+ +D+G Y C+A NSVG + L V D PS S S V GN R C Sbjct: 4767 LEILNLQHSDQGTYLCKASNSVGTATCCTELRVVDKPSFVKSFESTTVAVGNPLRLECQV 4826 Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376 ++ W +G + + A + + L I + D+ T C+A N Sbjct: 4827 DEDTGVSIIWMRDGKK------LHTTMDCKLAFEEKIACLDIQKSKLKDT-GTYTCTAAN 4879 Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEG 435 AGSS +TV + PP+ + L + M+ CT +PE + W+ Sbjct: 4880 EAGSSSCSSSVTV-----QEPPVFVKRLEPKILWKQGMSSRLSCTVKGSPELHVTWFLND 4934 Query: 436 EALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 + L + + + TN TL + DL +SDSG YTC + G S + V P Sbjct: 4935 KPLNSSEKHKITFKTNQATLEIIDLSESDSGNYTCEVMNEAGCESCSSQVTVKEP 4989 Score = 108 bits (260), Expect = 8e-22 Identities = 118/468 (25%), Positives = 183/468 (39%), Gaps = 31/468 (6%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDT-HRSIL--PAGGLFFLRATHGRVHSDAGVYWCEA 87 L C GS + W+K + +D H+ I A L R SD+G Y C A Sbjct: 5758 LECLVSGSLPINVTWFKENKEIEADEKHKCIFFENAASLEISRLDS----SDSGNYTCIA 5813 Query: 88 TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147 N G+ + + TL V +PES+ G V L G+P + W K+ + Sbjct: 5814 KNQAGSDQC-SGTLKVKEPPSIIE-KPESQDVIPGSKVQFNVLLS-GTPPLTINWFKDTK 5870 Query: 148 TLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT 206 + D + D ++ + A+ +D+G+Y C N G+ +S ATL + P Sbjct: 5871 EVSSGIDCSVQKNDTSSSIELFFAKPSDSGQYVCEVSNDVGS-DSCQATLFVKEPPKFTR 5929 Query: 207 GPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVI-- 263 PE + V + V F+C++ G P D W + G P + K+ SL +I Sbjct: 5930 KPEKITVVKPSQLVVFECQITGTPEIDTYWFKD-GNDISPSDKYKMTFVDSLARLEIISS 5988 Query: 264 -LADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEP 322 + D G Y CEA N G+ S S L V +PP + + + V +G+ A F C G Sbjct: 5989 DIKDSGVYYCEARNEAGSESCSMDLRVKEPPVLVKPLSPLEVVNGSNAYFECLVKGTAPF 6048 Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382 + W + S K+ D + L + D D C N GS Sbjct: 6049 EVTWEKDSKDI-----KSSLKHVILQKNDSIITLDVQKCDALDV-GEYQCIVANEVGSCS 6102 Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN- 441 + L++ + PP N + M F C +P I W + ++++ Sbjct: 6103 SQSTLSI-----KEPPSFVERIENVVTVLGKMVEFKCVVRGSPPLSIQWQKDESWILEDP 6157 Query: 442 --HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 R N TL + + SG YTC A + G+ L+V P Sbjct: 6158 SIQRTFENNVATLTIPVCESIHSGKYTCQAMNEAGQEKCFSTLVVQEP 6205 Score = 108 bits (259), Expect = 1e-21 Identities = 111/490 (22%), Positives = 199/490 (40%), Gaps = 31/490 (6%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-THRSILPAGGLFF 68 E P +++ + T + L GS + W + ++ D +R I Sbjct: 6652 EPPAFVKKLSNTTAISGEEVVLLTTVKGSQPMTVSWVQDKDHILRDGENRKITFENNEVT 6711 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVL 127 L+ + AG Y C+ N G A T ++ VL ++ +S G+ L Sbjct: 6712 LKVFKAD-STTAGKYTCQLKNDAGVAE---CTANLTVLEPAAIVDKTDSISVTAGEAAAL 6767 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAA 186 EC G+PE W K+G L ++ +L + ++D G Y +N Sbjct: 6768 ECTVS-GTPELKPKWFKDGVELSSGKKYKITFSKMISSLKLLSTERSDTGEYTFSIKNEV 6826 Query: 187 GTRESAIA-TLKIHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA----G 240 G+ A+ T+ I P L + +D + G S+ C+ G + W + Sbjct: 6827 GSDSCAMQLTVLDKIVPPLFSRKLKDTQSIVGKSMELDCKASGSAPLTISWFHNEVEIMS 6886 Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300 G N + + + +L++ + L+D G Y C+A NS GA S L V +PPS +P Sbjct: 6887 GPNYEITFTE--NTCTLKVPTLKLSDSGTYKCKAVNSAGAAETSASLVVKEPPSFVTTPQ 6944 Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360 V G FT T G + W G++ I+ G S + A+ +L +++ Sbjct: 6945 PVEALPGTTVTFTATVQGSTPMKLKW-FRGSKEIV-SGRSCE----IALRGDTAILELHN 6998 Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420 DK+ + C +N AG L V + N ++ + + CT Sbjct: 6999 IDKSHA-GEYTCQIINDAGKENCPVNLFV-----KEAAHFVKKLKNLSVEMGKSLILECT 7052 Query: 421 AICTPEPIIAWYFEGEALIQNHRRNV-TNDGTLVLKDL--DKSDSGTYTCVASSRHGKYV 477 +P+ ++ W+ +G+ + +++ N+ T + + +L+ L DK +G YTC S+ G + Sbjct: 7053 YAGSPKILVKWHKDGQEIYSSYKYNITTTESSCILECLNSDKEAAGKYTCEVSNDAGHDI 7112 Query: 478 WSGALLVDSP 487 A+ + P Sbjct: 7113 CEAAVSILEP 7122 Score = 107 bits (256), Expect = 2e-21 Identities = 117/495 (23%), Positives = 190/495 (38%), Gaps = 35/495 (7%) Query: 6 VTSGEAPYIIEQPLDVTVARHQ--PATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63 VT E P +++ L+ + Q + L+C GSP + W+ + S I Sbjct: 4890 VTVQEPPVFVKR-LEPKILWKQGMSSRLSCTVKGSPELHVTWFLNDKPLNSSEKHKITFK 4948 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYG--TARSRNATLHVAVLREEFRLEPESKQSAQ 121 L SD+G Y CE N G + S+ ++E RL + + Sbjct: 4949 TNQATLEIID-LSESDSGNYTCEVMNEAGCESCSSQVTVKEPPAFKKELRLV----EVVK 5003 Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD---GGNLVIQDARQTDAGRY 178 G T LEC G+ + W K+ + D++ ++V L I+ D G Y Sbjct: 5004 GCTAHLEC-EMTGTAPFEITWFKDKNPV--SSDTKYNIVSKETAAYLEIKTFESADVGDY 5060 Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238 QC N G + + A K+ P + E+ A GS+V Q + G V W + Sbjct: 5061 QCCISNDVG-KITTKAVAKLKDPPSFVKKVENTTAVLGSAVKLQGTIKGSAPITVQWFKD 5119 Query: 239 AGGGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295 + + + L + NV + G+Y+C+AEN G +TV +P Sbjct: 5120 TEIVRDDDPNITTTFENNIAVLAISNVAINHGGKYTCQAENEAGKQKCEATVTVQEPARF 5179 Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355 P ++V +G+ A C +G P+ + W +G M+ + + + V V Sbjct: 5180 VEKPPCISVTAGDSATLECKVSGSPDLKVKWFKDGKE------MAGGRKYKITFKENVAV 5233 Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415 L I ++ DS V N G + V PP+ + P +Q + + Sbjct: 5234 LKILSAERGDSSEYKV-EVSNRVGKEQCSCSINVLE-----PPVFSLKPQSQDVIPGTTV 5287 Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHR---RNVTNDGTLVLKDLDKSDSGTYTCVASSR 472 V T +I W+ E + ++ + TN +L L L S S YTC S+ Sbjct: 5288 VLTAAFTGTAPFMIKWFREDKEMLTGGTCFIKKETNSSSLELHALKPSQSAKYTCQVSND 5347 Query: 473 HGKYVWSGALLVDSP 487 GK + AL V P Sbjct: 5348 AGKVSCTAALFVKEP 5362 Score = 107 bits (256), Expect = 2e-21 Identities = 121/496 (24%), Positives = 190/496 (38%), Gaps = 29/496 (5%) Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62 D VT E P +++ + V + +L C GS I W K + H I Sbjct: 5541 DFLVTMKEPPSFVQKMDNTNVLLAKDVSLQCVLKGSMPMTISWMKDDHEIKESEHVQISF 5600 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122 + + ++ G Y C A N G S+ T V ++E + ++K + Sbjct: 5601 ENQTAVIYISSVQL-KHGGKYTCHAQNEAG---SQKCTA-VLTVKEPANITEQAKSVSVT 5655 Query: 123 --DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQ 179 D LEC G+ W K+G L ++ D +++ I A ++DAG Y Sbjct: 5656 VRDPATLECRYS-GTKVLKAKWLKDGNELTSGRKYKIQSSDTSSILKILSAEKSDAGEYT 5714 Query: 180 CIARNAAGTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 N AG E+ + L IKP ++ + GS +C V G +V W + Sbjct: 5715 FEVSNDAGRSSCEAVVTVLDQIIKPSFTRKLKETESIKGSFTQLECLVSGSLPINVTWFK 5774 Query: 238 SAGGGNMPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295 + + SL + + +D G Y+C A+N G+ SG L V +PPSI Sbjct: 5775 ENKEIEADEKHKCIFFENAASLEISRLDSSDSGNYTCIAKNQAGSDQCSGTLKVKEPPSI 5834 Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355 P S +V G+ +F +G P T+ W + S K ++ + + Sbjct: 5835 IEKPESQDVIPGSKVQFNVLLSGTPPLTINWFKDTKEVSSGIDCSVQKNDTSS---SIEL 5891 Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS-M 414 +D VC N GS + L V + PP T P T+ S + Sbjct: 5892 FFAKPSDSGQ----YVCEVSNDVGSDSCQATLFV-----KEPPKFTRKPEKITVVKPSQL 5942 Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL---DKSDSGTYTCVASS 471 VF C TPE W+ +G + + + +T +L ++ D DSG Y C A + Sbjct: 5943 VVFECQITGTPEIDTYWFKDGNDISPSDKYKMTFVDSLARLEIISSDIKDSGVYYCEARN 6002 Query: 472 RHGKYVWSGALLVDSP 487 G S L V P Sbjct: 6003 EAGSESCSMDLRVKEP 6018 Score = 89.4 bits (212), Expect = 5e-16 Identities = 112/476 (23%), Positives = 179/476 (37%), Gaps = 29/476 (6%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 + P +++ + T L GS ++W+K +V D + Sbjct: 5081 DPPSFVKKVENTTAVLGSAVKLQGTIKGSAPITVQWFKDTEIVRDDDPNITTTFENNIAV 5140 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 A + G Y C+A N G + AT+ V F +P GD+ LEC Sbjct: 5141 LAISNVAINHGGKYTCQAENEAGKQKCE-ATVTVQE-PARFVEKPPCISVTAGDSATLEC 5198 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGT 188 GSP+ V W K+G+ + ++ + L I A + D+ Y+ N G Sbjct: 5199 -KVSGSPDLKVKWFKDGKEMAGGRKYKITFKENVAVLKILSAERGDSSEYKVEVSNRVG- 5256 Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGGGNM 244 +E ++ + P P+ G++V G + W R GG Sbjct: 5257 KEQCSCSINVLEPPVFSLKPQSQDVIPGTTVVLTAAFTGTAPFMIKWFREDKEMLTGGTC 5316 Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN- 303 + K + SL L + + +Y+C+ N G VS + L V +PP + + Sbjct: 5317 FIK--KETNSSSLELHALKPSQSAKYTCQVSNDAGKVSCTAALFVKEPPKFVMKLDLTKL 5374 Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363 V +G++A C G PE ++ W N T I S DKY A D V L I+ Sbjct: 5375 VLNGSLATLECKVAGSPEISIRW--YKNETEI---GSDDKYQ-MAFTDSVATLRISSCCV 5428 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423 DS +C A + AGS +TV PP + S + +K V + Sbjct: 5429 EDS-GDYICQASSDAGSDRCSCLVTV----KEPPEFVKPFESKEI--VKGTDVVLEGTVS 5481 Query: 424 TPEPIIAWYFEGEALIQNHRRNV---TND-GTLVLKDLDKSDSGTYTCVASSRHGK 475 P F+ I+N RR++ T D L + + D+G Y C + G+ Sbjct: 5482 GSAPFEISCFKDSKQIRNDRRHIISLTKDVAALQILKFEPGDAGKYQCTVGNEVGQ 5537 Score = 83.8 bits (198), Expect = 3e-14 Identities = 113/490 (23%), Positives = 186/490 (37%), Gaps = 52/490 (10%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P +E+ +V + C GSP +I+W K ++ D + L Sbjct: 6111 EPPSFVERIENVVTVLGKMVEFKCVVRGSPPLSIQWQKDESWILEDPSIQRTFENNVATL 6170 Query: 70 RA-THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128 +HS G Y C+A N G + + TL V + +PE GD V E Sbjct: 6171 TIPVCESIHS--GKYTCQAMNEAGQEKCFS-TLVVQEPPQIIE-KPEVINVTAGDPVSFE 6226 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAG 187 C G+PE V W K+G+ ++ + ++ L +Q + D G Y N Sbjct: 6227 C-KVSGTPELKVKWSKDGKEVIPSRQHSLSYINNVSQLKLQSVQLEDKGTYVFEVSNHIS 6285 Query: 188 TRESAIA--TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 + + L+ I P I ++ G +V C++ G V W + G Sbjct: 6286 ACQCKVTLNVLEQIIPPSFIKPLMEMEEIIGKNVQIGCKISGSLPITVEWEKD---GTKL 6342 Query: 246 LGRVK---VLDDGSLRLDNVIL--ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300 GR K + D+ S+ LD L AD G Y+C+ N G+ SG L V + ++ PN Sbjct: 6343 SGRTKHKILQDENSVSLDIECLEKADTGTYTCKLANKAGSCECSGTLRVKESQAV--IPN 6400 Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360 + RF + G P T+ W + I P + F G+ L+ Sbjct: 6401 T-------TVRFKGSFKGTPPFTVKWFKDDTELICGP----------SCFTGLEGLS--- 6440 Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420 + ++++G+ + S+D PP + P+ + + + C Sbjct: 6441 -----CFLDLFAVGISHSGTYSCQ-----ISNDAEPPEFVQKLPAAKVVKMGEPLQLECK 6490 Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS---DSGTYTCVASSRHGKYV 477 T I+WY L +T D ++ + ++ S D+G YTC A + G Sbjct: 6491 VTGTAPLRISWYKNDAILSDGGNLRMTFDNSVAVLEISTSSFDDNGVYTCEAQNDAGTKS 6550 Query: 478 WSGALLVDSP 487 S AL + P Sbjct: 6551 CSTALTIKEP 6560 Score = 79.4 bits (187), Expect = 6e-13 Identities = 81/284 (28%), Positives = 117/284 (41%), Gaps = 22/284 (7%) Query: 253 DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PPSINLSPNSVNVESGNVA 310 D +L + V+ EGEY+CEA G S S +LTV PP ++ V G+ A Sbjct: 4573 DTYTLVITKVMKDHEGEYTCEAVGEAGKTSTSSHLTVIPRVPPVFRQRIQNLEVNVGSSA 4632 Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370 +F C P T W G H T + L I DS Sbjct: 4633 KFECEIEEAPGVTFKWFKSGTELRHSEKCRIISRHHT------SSLEIFSPAVADS-GEY 4685 Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-I 429 C A N GS KLTVT + PP + P + TL + A F C I EP+ + Sbjct: 4686 TCKASNRHGSDSCSAKLTVT---ELFPPEFVSKPDSMTLFVGKQAKFQC-VISGSEPMNV 4741 Query: 430 AWYFEGEAL-IQNHRRNVTNDGTLVLK--DLDKSDSGTYTCVASSRHGKYVWSGAL-LVD 485 W+ + A+ + +H + ++ L+ +L SD GTY C AS+ G L +VD Sbjct: 4742 VWHKDNIAISLDDHYKESSDKNRYFLEILNLQHSDQGTYLCKASNSVGTATCCTELRVVD 4801 Query: 486 SPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529 P + F + V+ G P + DT V++ W ++ K Sbjct: 4802 KP--SFVKSFESTTVA--VGNPLRLECQVDEDTGVSIIWMRDGK 4841 Score = 73.7 bits (173), Expect = 3e-11 Identities = 80/287 (27%), Positives = 113/287 (39%), Gaps = 25/287 (8%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH-S 78 ++TV Q +T RW + GV + + A R T + S Sbjct: 2929 EITVLEKQRSTFEFEVNEDDIEG-RWLRNGVEIQFSVDQRFNYAIIRKIHRLTITETYRS 2987 Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138 DAG Y T G RS TLHV + + S + + G P+P Sbjct: 2988 DAGEY----TFIAGKNRSI-VTLHVNIPEPPQIIRHMQPLSVEAGKPARFSVEVTGIPQP 3042 Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIATL 196 V W KN Q L G L +G L++ + DA +Y C A+N G S+ A+L Sbjct: 3043 QVSWYKNSQALS-SGFKCKFLREGNEHTLLLIEVFPEDAAQYNCEAKNDYGVATSS-ASL 3100 Query: 197 KIHIK-------------PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 + + P ++T ++ A G S FQCRV G+ L + + Sbjct: 3101 NVEVPEVVSPDTGAPLSPPVVLTPIQNTSANEGQSARFQCRVSGEDLTITWYCKDKEIKQ 3160 Query: 244 MPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 + RV D+ L + V DEGEY+C A NS G VS S L V Sbjct: 3161 SDIFRVSQFDENCQLEITRVYPEDEGEYTCVARNSAGMVSCSALLKV 3207 Score = 73.3 bits (172), Expect = 4e-11 Identities = 112/450 (24%), Positives = 170/450 (37%), Gaps = 47/450 (10%) Query: 178 YQCIARNAAGTRESAIATLK-IHIKPYLITGPEDVVAQTGSSVTFQCRV----GGDPLPD 232 ++ IA N AG + + T + + P G DV+ T +SVT GG L Sbjct: 19884 FRVIAINVAGLGKPSRTTESLVALDPIDPPGKPDVINVTRNSVTLMWTAPKYDGGHKLTG 19943 Query: 233 VLWRRSAGGGN--MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV- 289 + + G M V V + + ++ E+ A+N+ GA+SA T Sbjct: 19944 YMVEKLEHPGKTWMKANHVNV-QSCAYTVTDLQEGCTCEFRIRAKNAAGAISAPSETTEP 20002 Query: 290 ------YDPPSINLSP---NSVNVESGNVARFTCTAT-GRPEPTMFWSVEGNRTIIFPGM 339 Y+PP+I + P + V V++G T ++ G+P PT WS G Sbjct: 20003 LVCKDEYEPPTITIDPEMKDGVTVKAGGTIVITASSILGKPPPTAVWSKAGREF-----K 20057 Query: 340 SRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPI 399 S D ++ T+ + KN TI S N G + K+ V P PI Sbjct: 20058 SSDIVQISSTPTSSTLSIKYASRKNTGEYTITAS--NPFGIKDEKVKVKVLDVPGPPGPI 20115 Query: 400 ITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDK 459 + S + + + C+ + I E L+ D V L K Sbjct: 20116 EASSVSAEKCTLTWLPPEEDGG-CSIKSYILEKRETSRLLWTKLAENVMDCRYVASKLIK 20174 Query: 460 SDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTS 519 + + A +++G +G + P+ + D PGPP+KP NV+ + Sbjct: 20175 GNEYIFRVSAVNQYG----TGDVTQSGPV-------KMVDSFGPPGPPSKPEIDNVSKNA 20223 Query: 520 VTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIP 579 VT+SW + G S I GY VE R+ G R S+ + V + V L Sbjct: 20224 VTISWKRPTVDGGSDIRGYIVE---RKERRGMRWVRASK------KTVSDLRFKVSGLSE 20274 Query: 580 GITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 I Y F V EN G PS S V D Sbjct: 20275 EIEYEFRVTAENKAGFGEPSEPSQPVMTKD 20304 Score = 72.9 bits (171), Expect = 5e-11 Identities = 125/524 (23%), Positives = 196/524 (37%), Gaps = 78/524 (14%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 D+ V + A C P+ + W K G + + + L R+ SD Sbjct: 2839 DIKVTEKKKAVFECELS-EPNVQVTWMKDGQELELSERYKVSTERHVHRLMIQTVRM-SD 2896 Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPE-SKQSAQGDTVVLECLPPRGSPEP 138 AG Y A +S A N T+ +R E E + Q T E + Sbjct: 2897 AGEYSVVAGSSVSKA---NLTVEGKDVRISEPAEKEITVLEKQRSTFEFEV----NEDDI 2949 Query: 139 NVYWKKNGQTLLFDGDSRMHLV---DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195 W +NG + F D R + L I + ++DAG Y IA + +I T Sbjct: 2950 EGRWLRNGVEIQFSVDQRFNYAIIRKIHRLTITETYRSDAGEYTFIAG-----KNRSIVT 3004 Query: 196 LKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD 253 L ++I P +I + + + G F V G P P V W +++ + + K L Sbjct: 3005 LHVNIPEPPQIIRHMQPLSVEAGKPARFSVEVTGIPQPQVSWYKNSQALSSGF-KCKFLR 3063 Query: 254 DGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP------------PSINLS 298 +G+ L L V D +Y+CEA+N G ++S L V P P + L+ Sbjct: 3064 EGNEHTLLLIEVFPEDAAQYNCEAKNDYGVATSSASLNVEVPEVVSPDTGAPLSPPVVLT 3123 Query: 299 P-NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 P + + G ARF C +G + T+ W + + + + FD L Sbjct: 3124 PIQNTSANEGQSARFQCRVSGE-DLTITWYCKDKE------IKQSDIFRVSQFDENCQLE 3176 Query: 358 INDTDKNDSRNTIVCSAVNYAG----SSFVR--GKLTVTSDDDRPPPIITNGP--SNQTL 409 I D C A N AG S+ ++ G+ V + PP T+ P S +T+ Sbjct: 3177 ITRVYPED-EGEYTCVARNSAGMVSCSALLKVDGETEVMDYSSKFPPQATSSPLTSIKTI 3235 Query: 410 -------------PIKSMAV-------FPCTAICTPEPIIAWYFEGEAL-----IQNHRR 444 PI S V F P+P I+W+ + + + H Sbjct: 3236 QKDAIGQKPSFFQPIMSSVVAHGEVARFHACVSGIPKPEISWFHNQQPIKPTKNVVYHFD 3295 Query: 445 NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPI 488 +TN TL++ D +G YTC A + G+ S L V + Sbjct: 3296 EMTNTATLIIVDTFSEHAGQYTCKAVNIRGEAACSANLAVTEEV 3339 Score = 72.1 bits (169), Expect = 8e-11 Identities = 116/475 (24%), Positives = 170/475 (35%), Gaps = 52/475 (10%) Query: 10 EAPYI-IEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67 E PY+ +PL DV V + A C S +RW++ G + ++ G Sbjct: 12086 EPPYVEFTKPLHDVEVKEKESARFECEVSRE-SAKVRWFRDGNEIRKGKKYEMISEGVKR 12144 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPE--SKQSAQGDTV 125 L + V D Y C+A S + + V+ EE R + + + D+V Sbjct: 12145 ILIISKS-VFDDEAEYECDARTSKSSGM-------LTVVEEEARFTKNLANIEGTETDSV 12196 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIAR 183 L C + S E V W K Q L G H+ DG L+I+ R DAG Y C Sbjct: 12197 KLICEVSKPSAE--VTWYKGDQELPEVGRYE-HITDGKKRILIIKGLRMDDAGEYHCKLP 12253 Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 + T I L I P++ G F C V D +V W + GN Sbjct: 12254 TSQTTGNLRINELAAEF----IARPQNQEVVEGEKAQFVCSVSKDTY-EVKWLK----GN 12304 Query: 244 MPL---GRVKVLDDGSLRL---DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297 L + +++ +G R+ N L DEG + +G AS LTV + I Sbjct: 12305 TELQSDDKYEIISEGKKRVLIVKNCELKDEGGFVV----LIGTTRASADLTVLEKLRIIT 12360 Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 G C W ++ N T+ K+ D V L Sbjct: 12361 PLKDTKANEGQETVLNCEVNTEGAKAK-W-LKNNETLF----ESSKFIMVQK-DNVFSLR 12413 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417 I DT K+D N + A + +TV +D R I P + K F Sbjct: 12414 IKDTQKSDEANYTITLTNQRAEQAKSSANITVHEEDLR----IVVPPEDVDTQEKKAISF 12469 Query: 418 PCTAICTPEPIIAWYFEGEALIQNHR---RNVTNDGTLVLKDLDKSDSGTYTCVA 469 C + + W G+ + + R R TL +KD +D G YT +A Sbjct: 12470 TCK-VNRQNVTVQWMKAGQEITLSKRILYRVDKEKHTLTIKDCSLADEGEYTVIA 12523 Score = 70.1 bits (164), Expect = 3e-10 Identities = 78/306 (25%), Positives = 119/306 (38%), Gaps = 39/306 (12%) Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369 A F G P+P + W G + I+ G K G L I++ D+ND+ Sbjct: 30578 ATFVTKVVGHPKPVVKWYKNG-KEILADGA---KIKVQEFKGGYFQLVISNADENDAAAY 30633 Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429 + A N GS L V P+ G + P+P++ Sbjct: 30634 QI-RATNQLGSISTSMNLDVEVPAKIYLPLHLQGMGAVHAIRGEVVTIKIPISGKPDPVV 30692 Query: 430 AWYFEGEALIQN---HRRNVTNDGT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 W +G+ +I N H+ +T T + LK + + DSG Y A +R G + L Sbjct: 30693 TWQ-KGQEIINNTAYHQVIITRSFTSLVFLKGVQRKDSGYYIICAKNRFGMDKQTVEL-- 30749 Query: 485 DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFS 544 DV+ +P PP ++ ++TL+WS N G S I+ Y +E Sbjct: 30750 --------------DVADVPDPPKDVKVSDIGRDTLTLTWSPGND-GGSEIINYIIE--- 30791 Query: 545 RETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDS 604 P W+ +A+ ++ Y V SL Y F V EN G+S PS +D Sbjct: 30792 -------KCPTTGDRWIRVAQ-TSESQYTVMSLFGKTKYQFRVIAENRFGVSDPSAPTDP 30843 Query: 605 VTVGDD 610 VT +D Sbjct: 30844 VTTKED 30849 Score = 68.1 bits (159), Expect = 1e-09 Identities = 104/497 (20%), Positives = 191/497 (38%), Gaps = 22/497 (4%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68 GEAP + E D T + L C+ G P P I+WY+ G ++ + G Sbjct: 30163 GEAPCLKEDIKDTTTKLGESGILTCQIIGRPLPEIKWYRYGKELIQSRKYKMSSDGRNHS 30222 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128 L D G+Y C A N G + L A + + K A T + Sbjct: 30223 LSVMTDE-QEDEGLYTCRAVNEAGEIETSGKLLLQAAPQFHPGFPLKEKYYAGCGTSLRL 30281 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDA-RQTDAGRYQCIARNAA 186 + G P P + W + L + + + +LVI++ R+T+AGRY+ N Sbjct: 30282 HVVYIGRPIPQIMWFYGKKPLNPSENVIIENTESYTHLVIRNVQRKTNAGRYKVQLSNKF 30341 Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV----GGDPLPD-VLWRRSAGG 241 GT ++ + ++I KP L GP V A SSV + GG + + ++ +R A Sbjct: 30342 GTVDT-VLRVEIQDKPLLPEGPVVVDALLKSSVIISWKPPKDDGGSMITNYIVEKREAKE 30400 Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG---AVSASGYLTVYDPPSINLS 298 G + + R+ N+I + + A+N G ++ + + P Sbjct: 30401 GEQWHLVSSAVSGTTCRVPNLIESSGYYFRVSAQNQYGISESLEIPSVVIIKSPFEKPGV 30460 Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHA--TAVFDGVTVL 356 P V S V + +C + +P + + N + ++K+ A T + Sbjct: 30461 PQRPFVSS--VTKDSCVVSWKPPTSDGGAKIKNYFLEKREKKQNKWIAVTTGEIHETSYT 30518 Query: 357 TINDTDKNDSRNTIVCSAVNYAGS-SFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415 + + + C + S + + SD P + + + K+ A Sbjct: 30519 AKGLLEGFEYEFRVKCENIGGESDWSEISEPVIPKSDTALRAPFFKDELRDMCVKYKANA 30578 Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND-----GTLVLKDLDKSDSGTYTCVAS 470 F + P+P++ WY G+ ++ + + + LV+ + D++D+ Y A+ Sbjct: 30579 TFVTKVVGHPKPVVKWYKNGKEILADGAKIKVQEFKGGYFQLVISNADENDAAAYQIRAT 30638 Query: 471 SRHGKYVWSGALLVDSP 487 ++ G S L V+ P Sbjct: 30639 NQLGSISTSMNLDVEVP 30655 Score = 67.3 bits (157), Expect = 2e-09 Identities = 185/808 (22%), Positives = 290/808 (35%), Gaps = 82/808 (10%) Query: 37 GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96 G P+P I W K G + T ++ L+ D+G Y ATN+ GT Sbjct: 23972 GRPTPKIGWMKDGQALKETTRLNVSSTATSTVLKIKEAN-REDSGKYTITATNNIGTVTE 24030 Query: 97 RNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP--RGSPEPNVYWKKNGQTLLFDGD 154 A + + + P VV+ PP G + N Y + T + Sbjct: 24031 EVAI--IILDKPGPPTGPVKIDEVSATYVVISWEPPVYTGGCQINNYVVEKRDTTTTNWQ 24088 Query: 155 SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL---ITGPEDV 211 + + + I + +++ A N G S +T + P+ G V Sbjct: 24089 TVSATIARTTIKISKLKTGSEYQFRVFAENRYGKSGSIDSTPVVVSYPFTEPAAPGAPFV 24148 Query: 212 VAQTGSSVTFQCRV----GGDPLPDVLWRRSAGGGNMPLGRVKVL-DDGSLRLDNVILAD 266 + T +T + + GG P+ R + K+L D LR + + Sbjct: 24149 SSVTKDHMTIEWKPPSNNGGSPIIGYHLERKEKNSILWTKLNKLLITDTRLRTNGLEEGI 24208 Query: 267 EGEYSCEAENSVG---AVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPT 323 E EY AEN G + S + DP +P ++ V + N+ T + Sbjct: 24209 EYEYRVFAENIAGISPSSKVSESVVARDPCDPPGTPEAI-VITRNLITLQWTKPQYDGGS 24267 Query: 324 MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383 + R + G K T + D T TI + + R A N AG V Sbjct: 24268 VITGYIIERKKLPDGRWM-KASFTNIID--TQFTITGLHE-EQRYEFRVIARNAAGILSV 24323 Query: 384 RGKLT--VTSDDD-RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI--IAWYFEGEAL 438 + T +T+ D+ P + + + +K+ F + +P+ I W +G+ + Sbjct: 24324 PSESTGPITAQDEIEAPSVSMDSRFKDVIIVKAGDSFSIDSDIAGKPLPDIVWLKDGKEI 24383 Query: 439 IQ-NHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHF 494 R + + T L +KD + D G + S+ G PIN Sbjct: 24384 DSATPRMEIKSTITRTVLTVKDCIRVDGGHFVLSLSNVGGTK--------QVPIN----- 24430 Query: 495 FRAADVSSLPGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNT 553 V PGPP P+ V L WS + G +SI Y +E RET Sbjct: 24431 ---VKVLDRPGPPDGPLKVTGVAAEKCYLHWSHPSHDGGASISHYIIE--KRET------ 24479 Query: 554 PRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNS 613 + W V+ ++ Y V L+PG Y+F V N +G+ P S+ V + N Sbjct: 24480 --SRLSWTVVEPKIQAISYKVTKLLPGNEYIFRVMAVNKYGIGEPLE-SEPVLAKNPFNK 24536 Query: 614 LWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDN 673 G ST + I D IV E D + ++G + R D Sbjct: 24537 --PG---PPSTPEASAITRDSIVLTWERPEDDGGS-----------QIDGFVLEKR--DK 24578 Query: 674 ITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN-SRVAQTLD-DVP 731 I + ND+ F T L + YEF + G PS S + D P Sbjct: 24579 EGIRWTKCNKKRLNDLR-FRATGLTEGHFYEFRVSAENAAGVGTPSEPSEYYKACDATYP 24637 Query: 732 DGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQ 791 GPP N ++ ++TTV L WS P + ++GY +V D+ ++ V T Q Sbjct: 24638 PGPPNNPKVTDHSSTTVSLAWSRP-IYDGGAPVSGY--IVEAKDINEDEWTVCTPPTGVQ 24694 Query: 792 ATSLIMTNLTSGVSYSVQIAAETIIGLG 819 AT + L Y+ +I A I G G Sbjct: 24695 ATHFTVKKLKENAEYNFRICAVNIEGAG 24722 Score = 66.5 bits (155), Expect = 4e-09 Identities = 42/108 (38%), Positives = 52/108 (48%), Gaps = 10/108 (9%) Query: 496 RAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPR 555 +A D LP PP KP + T TSVTLSW++ G S + GY VE NT Sbjct: 25711 KAEDPLFLPSPPAKPKIIDSTKTSVTLSWNKPLFDGGSPVTGYMVEY--------RNT-- 25760 Query: 556 NSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603 N W V T + V L G Y+F+VR+ N G S PSP +D Sbjct: 25761 NDDDWTVGVNNTKSTEFTVVGLTSGTEYVFVVRSINKIGPSEPSPETD 25808 Score = 62.9 bits (146), Expect = 5e-08 Identities = 99/403 (24%), Positives = 163/403 (40%), Gaps = 59/403 (14%) Query: 422 ICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVW 478 + P+ + W +G +L + R N L+LK+ + D G YT ++ G+ Sbjct: 21808 VAQPKAAVVWQKDGISLKETTRVNTEVAERHLYLLLKEATRDDVGKYTIKITNSAGE--- 21864 Query: 479 SGALLVDSPINPNIHFFRAADVSSLPGPPTKPIT-HNVTDTSVTLSWSQNNKIGSSSILG 537 + IN V PGPPT PI VT SVTLSW G SI Sbjct: 21865 -----ATADIN--------VIVLDKPGPPTGPIKIEEVTADSVTLSWQPPEYEGGCSINN 21911 Query: 538 YQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSG 597 Y VE R+T + N W +++ V +T L G Y F + EN +G S Sbjct: 21912 YIVE--KRDTSTTN--------WQIVSATVARTTTKAARLKTGCEYQFRIAAENRYGKS- 21960 Query: 598 PSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILN 657 S + V + G+ T + ++ P K++ Sbjct: 21961 -SVIVSEHVVAQYPFEIPHPPGIPAVQS-----ATKESMVVVWNKPSSDGGSKILG---- 22010 Query: 658 FYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGK 717 Y++E + +++ + KTI+ + F+I L + +YEF + + + G Sbjct: 22011 -YHIES-----KEKNSLLWVKQNKTIIPD---TRFKIGGLEEGIEYEFRV--YAENIVGL 22059 Query: 718 PSNSRVAQ-TLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGI-ITGYNVVVNWLD 775 S+V++ + P PP E I+ ++V L+W+PP Q GI ITGY VV + Sbjct: 22060 SKASKVSEIQVARDPCDPPGKPEAVIVKRSSVTLRWTPP--QFDGGIKITGY--VVEKKE 22115 Query: 776 VPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGL 818 +P + M A + + T +++ L Y ++ A G+ Sbjct: 22116 LPNGRWMKASFANIIE-TEFVVSGLVEEQQYEFRVIARNAAGV 22157 Score = 62.9 bits (146), Expect = 5e-08 Identities = 53/176 (30%), Positives = 77/176 (43%), Gaps = 30/176 (17%) Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481 P+P I W +G AL Q R NV + TL +KD + D G Y V ++ G+ + Sbjct: 22892 PKPTITWNKDGSALKQTTRVNVADTAHHTTLTIKDATREDGGMYNIVVANVLGQQEATVE 22951 Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPIT-HNVTDTSVTLSWSQNNKIGSSSILGYQV 540 +++ PGPPT P+ V+ S+TLSW G I Y V Sbjct: 22952 III----------------LEKPGPPTGPVRIDEVSAESITLSWDPPTYTGGCQISNYIV 22995 Query: 541 EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596 + R+T + N WVV++ V +T V +L G Y F + EN +G S Sbjct: 22996 Q--KRDTTTTN--------WVVVSATVARTTLKVGNLKTGAEYQFRIFAENRYGKS 23041 Score = 61.7 bits (143), Expect = 1e-07 Identities = 83/303 (27%), Positives = 121/303 (39%), Gaps = 34/303 (11%) Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363 V++G+ R G P PT W ++G I G ++ T F TVL+I D + Sbjct: 17191 VKAGSTIRLPALMRGLPVPTAKWVIDGEE-IKSEGNTKID---TDNFS--TVLSIADCTR 17244 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN--QTLPIKSMAVFPCTA 421 N + + + N AGS V L VT D PI GP N + P + + Sbjct: 17245 NHT-GIYILTVSNSAGSKTV--SLNVTVLDVPAAPI---GPVNILEVTPDSMVIDWRPPK 17298 Query: 422 ICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481 P++ + E + V++ T + + G V K + GA Sbjct: 17299 DDGGSPVMNYIVEKRESNKETWGGVSSGSTSTRLKISRLQQGVEYVVRIRAENK-MGIGA 17357 Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541 L +P H F A PG P KP+ ++++ ++TL W+ G S I GY +E Sbjct: 17358 ALESAPTVAR-HQFEA------PGHPGKPVASDLSEDALTLGWTMPLFDGGSPISGYIIE 17410 Query: 542 VFSRETLSGNNTPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600 R G W+ + + + Y V L G Y F V EN G SGPSP Sbjct: 17411 ---RRHKGGK--------WIRVNKTPCKELRYRVLGLFEGNEYEFRVFAENIAGFSGPSP 17459 Query: 601 VSD 603 VSD Sbjct: 17460 VSD 17462 Score = 61.7 bits (143), Expect = 1e-07 Identities = 48/171 (28%), Positives = 76/171 (44%), Gaps = 6/171 (3%) Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQ 172 P+S A+ T V +P G P P V WKK TL G + L+I+D + Sbjct: 19659 PDSSYVAKEGTTVRLNIPITGIPAPAVIWKKGDVTLSDSGRISVESTTTNTVLLIRDCHR 19718 Query: 173 TDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV----GGD 228 DAG++ I RN+AGT+E+AI +K+ KP + +GP T ++T + GG Sbjct: 19719 GDAGKFTIILRNSAGTKEAAI-DIKVVGKPGICSGPIKFDEITAEAITVEWGPPKDDGGS 19777 Query: 229 PLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279 + + + N + + S+R+ + E + AEN G Sbjct: 19778 EVTNYFLEKRHSTANKWVTVASAIQKNSMRVTRLHDGTEYIFRVCAENKYG 19828 Score = 61.3 bits (142), Expect = 2e-07 Identities = 103/410 (25%), Positives = 157/410 (38%), Gaps = 57/410 (13%) Query: 207 GPEDVVAQTGSSVTFQ-CRVGGDPLPDVL--WR--RSAGGGNMPLGRVKVLDDGSLRLDN 261 G D+++ T S+T R D ++L W R AG + D + Sbjct: 30068 GEFDIISITKDSITIHWLRPESDGGKEILGYWIEFRQAGESAWKKCNKERSKDRQFTIGG 30127 Query: 262 VILADEGEYSCEAENSVG-------AVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314 ++ A E E+ AEN G A+ L+V + P + + G TC Sbjct: 30128 LMEATEYEFRVFAENETGLSRPRRTAMGIKTKLSVGEAPCLKEDIKDTTTKLGESGILTC 30187 Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374 GRP P + W G I SR KY ++ DG TD+ + C A Sbjct: 30188 QIIGRPLPEIKWYRYGKELI----QSR-KYKMSS--DGRNHSLSVMTDEQEDEGLYTCRA 30240 Query: 375 VNYAGSSFVRGKLTVTSDDDRPP--PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432 VN AG GKL + + P P+ + ++ V+ I P P I W+ Sbjct: 30241 VNEAGEIETSGKLLLQAAPQFHPGFPLKEKYYAGCGTSLRLHVVY----IGRPIPQIMWF 30296 Query: 433 FEGEALIQNHRRNVTNDGT-----LVLKDLD-KSDSGTYTCVASSRHGKYVWSGALLVDS 486 + + L N NV + T LV++++ K+++G Y S++ G VD+ Sbjct: 30297 YGKKPL--NPSENVIIENTESYTHLVIRNVQRKTNAGRYKVQLSNKFG--------TVDT 30346 Query: 487 PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRE 546 + I D LP P + + +SV +SW G S I Y VE RE Sbjct: 30347 VLRVEIQ-----DKPLLPEGPV--VVDALLKSSVIISWKPPKDDGGSMITNYIVE--KRE 30397 Query: 547 TLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596 G W +++ V T V +LI Y F V +N +G+S Sbjct: 30398 AKEGEQ-------WHLVSSAVSGTTCRVPNLIESSGYYFRVSAQNQYGIS 30440 Score = 60.1 bits (139), Expect = 4e-07 Identities = 79/323 (24%), Positives = 135/323 (41%), Gaps = 38/323 (11%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 PGPP K ++ +VTLSW + ++ G S I GY VE + P + + W+ Sbjct: 13598 PGPPYKLEPSDIAKDAVTLSWYEPDEDGGSPITGYWVERYE---------PDHDK-WIRC 13647 Query: 564 AR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLW-EGTGVS 621 + + T++ VK L Y F V EN G PS +D + + D + W G Sbjct: 13648 NKLPIRDTNFRVKGLPTRKKYKFRVLAENLAGPGKPSKETDQILIKDPIDPPWAPGKPTV 13707 Query: 622 NSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNI-TIEYEM 680 + L E I+S ++L+ G + R DNI ++E+ + Sbjct: 13708 KDVAKTSAFLQWTKPEHDGGAKIESYIVELL--------KSGTDEWVRVADNIPSLEHFL 13759 Query: 681 KTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEM 740 K ++ + S F + ++ + E +PS+ + + + P PP + + Sbjct: 13760 KGLMEKQEYS-FRVRAVNVAGESE----------PSEPSDPVLCKERLN-PPSPPRWLLV 13807 Query: 741 FILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNL 800 + + LKW+ PE ++G N +V DV K A++TTV + +T L Sbjct: 13808 VSSSRNSAELKWTAPE---RDGGSPITNYIVEKRDV-RRKGWQAVDTTVKE-LKYTVTPL 13862 Query: 801 TSGVSYSVQIAAETIIGLGPFSQ 823 G Y ++AAE +G F + Sbjct: 13863 NEGSLYVFRVAAENAVGPSEFCE 13885 Score = 59.7 bits (138), Expect = 5e-07 Identities = 94/405 (23%), Positives = 156/405 (38%), Gaps = 36/405 (8%) Query: 99 ATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH 158 A L V EF + + + V EC P V W K+GQ L ++ Sbjct: 2822 AKLFVEARVIEFTKHIKDIKVTEKKKAVFEC--ELSEPNVQVTWMKDGQELELSERYKVS 2879 Query: 159 LVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP--EDVVAQT 215 + L+IQ R +DAG Y +A ++ A L + K I+ P +++ Sbjct: 2880 TERHVHRLMIQTVRMSDAGEYSVVAGSSVSK-----ANLTVEGKDVRISEPAEKEITVLE 2934 Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR----VKVLDDGSLRLDNVILADEGEYS 271 TF+ V D + + W R+ + + + L + +D GEY+ Sbjct: 2935 KQRSTFEFEVNEDDI-EGRWLRNGVEIQFSVDQRFNYAIIRKIHRLTITETYRSDAGEYT 2993 Query: 272 CEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGN 331 A + V+ ++ + +PP I ++VE+G ARF+ TG P+P + W N Sbjct: 2994 FIAGKNRSIVTL--HVNIPEPPQIIRHMQPLSVEAGKPARFSVEVTGIPQPQVSW--YKN 3049 Query: 332 RTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL---- 387 + G K + T+L I ++ ++ C A N G + L Sbjct: 3050 SQALSSGF---KCKFLREGNEHTLLLIEVFPEDAAQYN--CEAKNDYGVATSSASLNVEV 3104 Query: 388 --TVTSDDDRP--PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR 443 V+ D P PP++ N + A F C + + I WY + + + Q+ Sbjct: 3105 PEVVSPDTGAPLSPPVVLTPIQNTSANEGQSARFQC-RVSGEDLTITWYCKDKEIKQSDI 3163 Query: 444 RNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485 V+ + L + + D G YTCVA + G S L VD Sbjct: 3164 FRVSQFDENCQLEITRVYPEDEGEYTCVARNSAGMVSCSALLKVD 3208 Score = 59.7 bits (138), Expect = 5e-07 Identities = 55/199 (27%), Positives = 84/199 (42%), Gaps = 16/199 (8%) Query: 5 YVTSGEAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63 ++T+ + P + PL VTV + TL+C GSP I+W K + S + I Sbjct: 7500 HITAQKVPPSFDLPLKPVTVNEGETLTLSCHVRGSPPLKIQWMKDRRELSSSANTKITFV 7559 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE--------FRLE-P 114 G L T +D+G Y C+ATN G A A + F +E P Sbjct: 7560 DGTATLEMTRVS-KTDSGDYLCKATNEAGNKPGAPAPAQAAPSPPQEVKKFDNLFFIEVP 7618 Query: 115 ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG---NLVIQDAR 171 +S + T G P PNV W K + G R+ + G + I++ Sbjct: 7619 KSVHIVEKGTATF-IAKVGGDPIPNVKWMKGKWRQMTHG-GRISIEQKGQEAKMEIKEVT 7676 Query: 172 QTDAGRYQCIARNAAGTRE 190 ++D+G+Y+C+A N G E Sbjct: 7677 KSDSGQYRCVASNKHGEIE 7695 Score = 59.7 bits (138), Expect = 5e-07 Identities = 83/337 (24%), Positives = 137/337 (40%), Gaps = 39/337 (11%) Query: 274 AENSVGAVS----ASGYLTV---YDPPSINLSPNS---VNVESGNVARFTCTATGRPEPT 323 A+N+ G S ++G +TV DPP I + V +++G + R +GRP P Sbjct: 25396 AKNAAGLFSEPSESTGPVTVKDDVDPPRITIEDKLRQLVVIKAGEILRIDAEISGRPIPV 25455 Query: 324 MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383 + W+ +G ++ ++ ++ T++ + D + DS V + N AG+ + Sbjct: 25456 ISWAKDGKEI-----EAKARFEISSTLTSTTLI-VRDAIRRDS-GQYVLTLQNVAGTRSL 25508 Query: 384 RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR 443 V DRP GPS+ L I + CT P P E + I R Sbjct: 25509 AVNCKVL---DRP------GPSSGPLDITGLTAEKCTLTWGP-PQENGGAEIQHYIVEKR 25558 Query: 444 RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSL 503 TLV D+ K+ + T + + G + +A D ++ Sbjct: 25559 ETSRLAWTLVYADM-KATTCKVTKLLKGNEYIFRVRGVNKYGTGEALESDPAKAMDPFTV 25617 Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 P PT +VT ++T+ W + G SSI GY +E RE ++ WV + Sbjct: 25618 PAAPTDVEVTSVTSEAMTICWERPISDGGSSISGYVIE--KRE--------KSGLRWVRV 25667 Query: 564 ARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599 ++ V+ +L G Y + V EN+ GLS PS Sbjct: 25668 NKKPVYDLRVKASNLREGCEYEYRVFAENAAGLSAPS 25704 Score = 58.8 bits (136), Expect = 8e-07 Identities = 49/193 (25%), Positives = 86/193 (44%), Gaps = 7/193 (3%) Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGG 65 T+ AP+ ++ D+ V AT + G P P ++WYK G +++D + + G Sbjct: 30556 TALRAPFFKDELRDMCVKYKANATFVTKVVGHPKPVVKWYKNGKEILADGAKIKVQEFKG 30615 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGT-ARSRNATLHV-AVLREEFRLEPESKQSAQGD 123 +F +DA Y ATN G+ + S N + V A + L+ A Sbjct: 30616 GYFQLVISNADENDAAAYQIRATNQLGSISTSMNLDVEVPAKIYLPLHLQGMGAVHAIRG 30675 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLV-IQDARQTDAGRYQC 180 VV +P G P+P V W+K GQ ++ + ++ +LV ++ ++ D+G Y Sbjct: 30676 EVVTIKIPISGKPDPVVTWQK-GQEIINNTAYHQVIITRSFTSLVFLKGVQRKDSGYYII 30734 Query: 181 IARNAAGTRESAI 193 A+N G + + Sbjct: 30735 CAKNRFGMDKQTV 30747 Score = 58.4 bits (135), Expect = 1e-06 Identities = 109/457 (23%), Positives = 177/457 (38%), Gaps = 60/457 (13%) Query: 374 AVNYAGSSFVRGKLT--VTSDDD-RPPPIITNGPSNQTLPIKSMAVFPCTA--ICTPEPI 428 A N AG S V T +T+ D+ PP I + +Q + + + F A + P P Sbjct: 22151 ARNAAGVSSVPSDSTGAITAKDEVDPPQIDLDAKYSQNVVVNAGESFRIDAGILGKPIPS 22210 Query: 429 IAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485 + W GE L R + N TL +K+ + D G YT + + G+ +++++ Sbjct: 22211 VHWIKSGEELTNTARLEIKNTDFTTTLSVKEAIRVDGGQYTLLLKNVGGEK----SVIIN 22266 Query: 486 SPINPNIHFFRAADVSSLPGPPTKPIT-HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFS 544 V PGPP PI+ + VT +SW G + + Y VE Sbjct: 22267 ------------VKVLDRPGPPDGPISIYGVTSEKCCISWKTPLHDGGAEVSHYIVE--R 22312 Query: 545 RETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDS 604 RET + W V+ +V + + L+PG Y+F V N +G+ P SD Sbjct: 22313 RET--------SRLVWTVVELKVQTLNLKITKLLPGNEYIFRVIPVNKYGIGEPLE-SDP 22363 Query: 605 VTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGL 664 V +N SN +NI D +V E D + + G Sbjct: 22364 VIA---ANPFVTPEAPSNVEV--SNITKDSMVITWERPTNDGGSA-----------ITGY 22407 Query: 665 FIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRV- 723 + R + + K ++ F +T L + YEF + GKPS V Sbjct: 22408 IVEKRDKEGVRWTRCNKRVVSE---LRFRVTGLLEMRSYEFRVSAENAAGVGKPSPPTVY 22464 Query: 724 AQTLDDV-PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSM 782 + D V GPP N ++ ++ +V L WS P + +G + +V +V +++ + Sbjct: 22465 FKAADPVFKPGPPNNPKVAYVSRASVVLHWSKP---IYDGGCEIQSYIVEACEVTSDEWV 22521 Query: 783 VAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819 + + T L Y +I A IG+G Sbjct: 22522 MCTPPSGITETRFEAKKLLEKHEYKFRICAVNKIGVG 22558 Score = 58.4 bits (135), Expect = 1e-06 Identities = 82/316 (25%), Positives = 123/316 (38%), Gaps = 47/316 (14%) Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363 V G V R + G+P PT W+ EG R I M A + T L I + + Sbjct: 29781 VRQGGVIRLSVPIKGKPLPTCKWTKEG-RDISHRAM-------IATSEERTELVIKEAHR 29832 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP-PIITNGPSNQTLPIK--------SM 414 +D+ T N G V K+ V D P P+ + +++ + Sbjct: 29833 DDT-GTYDLVLENKCGRKAVYIKVKVIGRPDPPEGPLEFDDIQARSVRVSWRPPSDDGGS 29891 Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 +F P AWY ++ D +LV+K L ++ + A ++ G Sbjct: 29892 DIFGYIVERREVPKAAWYTVDSRVV---------DTSLVVKGLKENVEYHFKITAENQFG 29942 Query: 475 KYVWSGALLVDSPINPNIHFFRAADVSSLPGPPT-KPITHNVTDTSVTLSWSQNNKIGSS 533 S +L D + P P PP+ P +VT T++ LSWS+ G S Sbjct: 29943 I---SKSLKSDESVTPKTPLCP-------PEPPSFPPEIMDVTKTTIGLSWSRPKDDGGS 29992 Query: 534 SILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSH 593 + GY VE R +S R+++ + T Y + LIP Y F V +N Sbjct: 29993 RVTGYYVE---RREISTEKWVRHNK------THITTTMYTLTGLIPDAEYQFRVVAQNDI 30043 Query: 594 GLSGPSPVSDSVTVGD 609 G S P PVS+SV D Sbjct: 30044 GQSEPGPVSESVVCKD 30059 Score = 58.4 bits (135), Expect = 1e-06 Identities = 59/197 (29%), Positives = 85/197 (43%), Gaps = 15/197 (7%) Query: 134 GSPEPNVYWKKNGQTLLFDGDS-RMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGTRE 190 G P+P V W KNG+ +L DG ++ GG LVI +A + DA YQ A N G+ Sbjct: 30586 GHPKPVVKWYKNGKEILADGAKIKVQEFKGGYFQLVISNADENDAAAYQIRATNQLGSIS 30645 Query: 191 SAI-ATLKIHIKPYL---ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 +++ +++ K YL + G V A G VT + + G P P V W++ N Sbjct: 30646 TSMNLDVEVPAKIYLPLHLQGMGAVHAIRGEVVTIKIPISGKPDPVVTWQKGQEIINNTA 30705 Query: 247 GRVKVLD---DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303 ++ + L V D G Y A+N G + L V D P P V Sbjct: 30706 YHQVIITRSFTSLVFLKGVQRKDSGYYIICAKNRFGMDKQTVELDVADVPD---PPKDVK 30762 Query: 304 VESGNVARFTCTATGRP 320 V ++ R T T T P Sbjct: 30763 V--SDIGRDTLTLTWSP 30777 Score = 58.0 bits (134), Expect = 1e-06 Identities = 35/136 (25%), Positives = 72/136 (52%), Gaps = 7/136 (5%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVI 167 F +P S + ++G T + L G P P+ +W +GQ ++ D ++ + + G ++++ Sbjct: 1231 FVQKPSSFRCSEGQTARFD-LKVVGRPMPDTFWFHSGQQVVNDYTHKIVVKEDGTQSMIV 1289 Query: 168 QDARQTDAGRYQCIARNAAG-TRESAIATLKIH---IKPYLITGPEDVVAQTGSSVTFQC 223 A D+G + +A+N AG T S T++ ++P I +++ + GS V Sbjct: 1290 VPAMPQDSGEWTVVAQNRAGKTTVSMTLTVEAKENLVRPQFIEKLKNISVKEGSLVELAV 1349 Query: 224 RVGGDPLPDVLWRRSA 239 + G+PLPD++W +++ Sbjct: 1350 KAIGNPLPDIVWLKNS 1365 Score = 57.6 bits (133), Expect = 2e-06 Identities = 81/322 (25%), Positives = 120/322 (37%), Gaps = 39/322 (12%) Query: 292 PPSINLSPNS---VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348 PP I L + VN+ + + R GRP P + WS E + R T Sbjct: 21493 PPEIELDSDLRKVVNIRACSTLRLFVPVKGRPAPEIRWSREKGEPL-----DRASIEITP 21547 Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408 F T L I + D+ D ++ + N +G+ + V P Q Sbjct: 21548 SF---TTLLIENVDRFDGGKYML-TVENSSGTKTAFINVRVLDTPGAP----------QN 21593 Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468 L IK + + I P P+I +G + I+++ ++ S T + Sbjct: 21594 LTIKEITKDSVSLIWDP-PVI----DGGSRIRHYIVEKRESTRKAYSIVNASCPKTSWRI 21648 Query: 469 ASSRHGKYVWSGALLVDS-PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527 + G + L + + + A +S P PP K VT SVTLSW + Sbjct: 21649 GDLQEGNLYFFRILAENEYGVGLPVETMEAIKISERPLPPGKVTLKEVTSNSVTLSWEKP 21708 Query: 528 NKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIV 587 + G S I GY VE + G +NS W + V T VV L G Y F + Sbjct: 21709 DHDGGSRITGYIVE------MQG----KNSDKWTQV-MTVKVTEAVVVGLTQGEEYSFRI 21757 Query: 588 RTENSHGLSGPSPVSDSVTVGD 609 N G+S P P+S V D Sbjct: 21758 SATNEKGISDPRPLSVPVIAKD 21779 Score = 57.2 bits (132), Expect = 3e-06 Identities = 50/182 (27%), Positives = 79/182 (43%), Gaps = 25/182 (13%) Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 P P++ W E + L Q R N+ N + + ++++ + G+Y +G ++ Sbjct: 20729 PRPLVVWKKEDQELKQTQRINIENTASSTILNINE--------IKRKDGGQYSMTGKNIL 20780 Query: 485 DSPINPNIHFFRAADVSSLPGPPTKPIT-HNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543 + + NI V +PGPPT PI V+ V +SW G I Y VE+ Sbjct: 20781 GT-VTENI----TVQVHDIPGPPTGPIKLDEVSCDYVLISWEAPENDGGVPINNYIVEM- 20834 Query: 544 SRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603 RET W+ +A V +T + L GI Y F V+ +N +G+ GP S Sbjct: 20835 -RET--------TGTSWMELAATVIRTTFKAARLTTGIEYQFRVKAQNRYGV-GPYITSG 20884 Query: 604 SV 605 V Sbjct: 20885 PV 20886 Score = 56.8 bits (131), Expect = 3e-06 Identities = 84/332 (25%), Positives = 132/332 (39%), Gaps = 57/332 (17%) Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352 PS L+ N+ +V+SG + GRP P + W +G +R +TA Sbjct: 23947 PSFKLTFNTYSVQSGEDLKVEIPFKGRPTPKIGWMKDGQ---ALKETTRLNVSSTAT--- 24000 Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412 TVL I + ++ DS + +A N G TVT + II + P T P+K Sbjct: 24001 STVLKIKEANREDSGKYTI-TATNNIG--------TVT---EEVAIIILDKPGPPTGPVK 24048 Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNH---RRNVTNDG-----------TLVLKDLD 458 V + + EP + + G I N+ +R+ T T+ + L Sbjct: 24049 IDEVSATYVVISWEPPV---YTGGCQINNYVVEKRDTTTTNWQTVSATIARTTIKISKLK 24105 Query: 459 KSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDT 518 + A +R+GK SG+ + +P+ + F + P P P +VT Sbjct: 24106 TGSEYQFRVFAENRYGK---SGS-IDSTPVVVSYPF-------TEPAAPGAPFVSSVTKD 24154 Query: 519 SVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSL 577 +T+ W + G S I+GY +E +NS W + + + T L Sbjct: 24155 HMTIEWKPPSNNGGSPIIGYHLE----------RKEKNSILWTKLNKLLITDTRLRTNGL 24204 Query: 578 IPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 GI Y + V EN G+S S VS+SV D Sbjct: 24205 EEGIEYEYRVFAENIAGISPSSKVSESVVARD 24236 Score = 56.4 bits (130), Expect = 4e-06 Identities = 60/218 (27%), Positives = 91/218 (41%), Gaps = 33/218 (15%) Query: 388 TVTSDDD-RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-YFEGEALIQNHRR- 444 +VT+ D+ PP +Q L + + F A +PI A +F+G+ ++N R Sbjct: 23248 SVTAKDEVEPPTYEVASEYSQILTVNAGDTFSLEASVLGKPIPAMQWFKGDVEVENSARA 23307 Query: 445 ---NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVS 501 N LV+KD + D G YT S+ G ++ N+ V Sbjct: 23308 EIKNTDFKAVLVVKDAIRIDGGQYTLHLSNVAG----------SKSVSFNVR------VL 23351 Query: 502 SLPGPPTKPIT-HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGW 560 PGPP P+T VT+ +LSW G SSI Y ++ RET + W Sbjct: 23352 DRPGPPEGPLTVSGVTNEKCSLSWLPPRHDGGSSISYYVIQ--KRET--------SRLAW 23401 Query: 561 VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598 V++ T + V L+ G Y+F V N +G+ P Sbjct: 23402 TVVSGDCGATMFKVTKLLKGNEYIFRVMAVNKYGVGEP 23439 Score = 56.0 bits (129), Expect = 6e-06 Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 7/129 (5%) Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA---GGGNMPLGRVKVLDDGS-LRLDNVIL 264 + VVA GS+ TF+ +V G+P+P+V W R +P ++ D + L + V Sbjct: 13 QSVVALEGSAATFEAQVSGNPVPEVSWFRDGQVLTAAALPGAQISFSDGRAVLMIPAVTA 72 Query: 265 ADEGEYSCEAENSVGAVSASGYLTV---YDPPSINLSPNSVNVESGNVARFTCTATGRPE 321 A G +S A N G +++ L V PP+ S+ V G+ R TG P Sbjct: 73 AHSGRFSVRATNGAGQATSTAELLVTAETAPPNFIQRLQSLTVRQGSQVRLDVRVTGIPA 132 Query: 322 PTMFWSVEG 330 P + + EG Sbjct: 133 PVVKFYREG 141 Score = 56.0 bits (129), Expect = 6e-06 Identities = 74/298 (24%), Positives = 120/298 (40%), Gaps = 18/298 (6%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKV---LDDGSL 257 P+ + P G SV F C++GG P P + W++S G + G R +V D G Sbjct: 875 PFFVKKPVVQKLVEGGSVVFVCQIGGSPKPHIYWKKS--GVPLTTGYRYRVSHNKDTGEC 932 Query: 258 RLD-NVILADE-GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315 +L+ ++ AD+ GEY+ A+N G SAS L + + V + A Sbjct: 933 KLEISMTFADDAGEYTIFAKNQHGETSASTSLLEEEEFEAYMKKQDVTYVTEVTAMVQEP 992 Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN-TIVCSA 374 P + E + +I M++ + F T I+ ++ + I Sbjct: 993 KVADVPPVVVSEYE--KELIQRRMAQ-QTQMMQTFISETEFQISAIERKIIQEIEIRILK 1049 Query: 375 VNYAGSSFVRG-KLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWY 432 + Y G ++ + + + P ++ M V F C P P IAWY Sbjct: 1050 ITYQELVIEDGEEMVINVAEHEAVASSFSTPVKSYRILEGMGVTFHCKMGGKPLPKIAWY 1109 Query: 433 FEGEALIQ--NHRRNVTNDG--TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486 +G+ + ++ V DG +L L + D G YT AS+ G V SG L V+S Sbjct: 1110 KDGKRIKHGGRYQMEVLQDGRASLRLPVVLPEDEGIYTAFASNMKGNAVSSGKLYVES 1167 Score = 55.6 bits (128), Expect = 8e-06 Identities = 33/112 (29%), Positives = 53/112 (47%), Gaps = 2/112 (1%) Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556 A D PGPP + T TS+TLSW++ G + ++GY VE+ + + G Sbjct: 18155 AKDPIEPPGPPGSLKVVDSTKTSITLSWAKPVYDGGAPVIGYLVEMRDKVEMEGEQVRDP 18214 Query: 557 SRGW--VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVT 606 GW + ++ T Y + +L Y F V +N G+ P+ V D+V+ Sbjct: 18215 EEGWKKCNTSGQLVLTEYTISNLDERQEYEFRVSAQNQVGMGRPANVKDAVS 18266 Score = 55.6 bits (128), Expect = 8e-06 Identities = 47/185 (25%), Positives = 79/185 (42%), Gaps = 30/185 (16%) Query: 425 PEPIIAWYFEGEALIQNHR---RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481 P+PII W + L ++ + R N +L++++ K ++G YT V ++ K + Sbjct: 27226 PKPIIQWMKDDVILKESEQVRFRQTENKASLIVRNARKENAGKYTLVLDNKLVKNFFDIK 27285 Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSILGYQV 540 ++ P P P PI + + S+ +SW + G I Y V Sbjct: 27286 VITLGP----------------PSQPIGPIRFDEIKAQSIIISWDVPQEDGGGEITCYSV 27329 Query: 541 EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600 E RET + W ++ V +T + + +L+ G Y F VR EN +G+S P Sbjct: 27330 E--KRET--------SQAAWKIVCSSVVRTTFKIPNLVKGTEYQFRVRAENKYGVSDPLT 27379 Query: 601 VSDSV 605 D V Sbjct: 27380 SPDVV 27384 Score = 55.2 bits (127), Expect = 1e-05 Identities = 60/227 (26%), Positives = 89/227 (39%), Gaps = 20/227 (8%) Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241 AR T ES + L KP + P G + F +V G P+PD W S Sbjct: 1212 ARRLDDTDESQLERL---YKPVFVQKPSSFRCSEGQTARFDLKVVGRPMPDTFWFHSGQQ 1268 Query: 242 -GNMPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP-----P 293 N ++ V +DG S+ + + D GE++ A+N G + S LTV P Sbjct: 1269 VVNDYTHKIVVKEDGTQSMIVVPAMPQDSGEWTVVAQNRAGKTTVSMTLTVEAKENLVRP 1328 Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV--FD 351 +++V+ G++ A G P P + W N II P KY + Sbjct: 1329 QFIEKLKNISVKEGSLVELAVKAIGNPLPDIVWL--KNSDIISP----HKYPHIKIEGAK 1382 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398 G I T +DS +A+N AG R ++ V + P P Sbjct: 1383 GQAHFQIPQTSGSDSA-WYTATAINKAGRDTTRCRVNVEVEYTEPVP 1428 Score = 55.2 bits (127), Expect = 1e-05 Identities = 75/331 (22%), Positives = 137/331 (41%), Gaps = 33/331 (9%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 A I +P + V + A C + ++W KG + SD I+ G L Sbjct: 12267 AAEFIARPQNQEVVEGEKAQFVCSVS-KDTYEVKWLKGNTELQSDDKYEIISEGKKRVLI 12325 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVLEC 129 + + + G GT R A+ + VL + + P + ++ +G VL C Sbjct: 12326 VKNCELKDEGGFVVL-----IGTTR---ASADLTVLEKLRIITPLKDTKANEGQETVLNC 12377 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIARNAA 186 + W KN +TL F+ S+ +V N L I+D +++D Y N Sbjct: 12378 --EVNTEGAKAKWLKNNETL-FES-SKFIMVQKDNVFSLRIKDTQKSDEANYTITLTNQR 12433 Query: 187 GTRESAIATLKIHIKPY-LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 + + A + +H + ++ PEDV Q +++F C+V + V W ++ G + Sbjct: 12434 AEQAKSSANITVHEEDLRIVVPPEDVDTQEKKAISFTCKVNRQNV-TVQWMKA--GQEIT 12490 Query: 246 LGRVKVL-----DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS-INLSP 299 L + ++L + +L + + LADEGEY+ A G A+ L + + P+ Sbjct: 12491 LSK-RILYRVDKEKHTLTIKDCSLADEGEYTVIA----GPDKATAELIISEAPTDFTAQL 12545 Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEG 330 + + A F+C T + + + W +G Sbjct: 12546 SDQTITEFEDAEFSCELT-KEKADIKWYRDG 12575 Score = 54.4 bits (125), Expect = 2e-05 Identities = 82/325 (25%), Positives = 127/325 (39%), Gaps = 39/325 (12%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 PGPP +V V L W G S I Y V+ RET N W + Sbjct: 19058 PGPPASVRISHVFADRVKLRWEPPLADGGSEITNYIVD--KRETSRAN--------WAQV 19107 Query: 564 ARRVHQ--THYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVS 621 ++ T V+ LI G Y F + EN +G+ P V+ SV + + ++ G Sbjct: 19108 TANINGQITDCSVEKLIEGHEYEFRISAENKYGVGDPI-VTSSVM----AKNPFDVPGPC 19162 Query: 622 NSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNIT-IEYEM 680 N+ DH+ +A D K L G + R ++ ++ Sbjct: 19163 EPPVI-TNVTRDHMTVTWKAPANDGKATIL-----------GYMVEKRETQDLNWVKVNR 19210 Query: 681 KTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN-SRVAQTLDDV-PDGPPINI 738 + ++ +G L + T+YEF +I K GKPS+ S LD V P GPP Sbjct: 19211 RPVIDRTIKAG----GLTEGTEYEFRVIALNKAGLGKPSDPSSGVLALDPVYPPGPPAFP 19266 Query: 739 EMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMT 798 ++ +++ L W+ P I+ GY +V + A + M QAT +T Sbjct: 19267 KVVDSTHSSISLSWTKPAYDGGCEIL-GY--LVEFKRADAEEWMKCNVPKNLQATKFNVT 19323 Query: 799 NLTSGVSYSVQIAAETIIGLGPFSQ 823 L Y +++A IG G S+ Sbjct: 19324 GLIDNTEYQFRVSAVNKIGFGEPSE 19348 Score = 53.6 bits (123), Expect = 3e-05 Identities = 61/208 (29%), Positives = 81/208 (38%), Gaps = 20/208 (9%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64 +V E P II ++V +PA + G P P + WYK + S L G Sbjct: 3006 HVNIPEPPQIIRHMQPLSVEAGKPARFSVEVTGIPQPQVSWYKNSQALSSGFKCKFLREG 3065 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV-----------LREEFRLE 113 L DA Y CEA N YG A S +A+L+V V L L Sbjct: 3066 NEHTLLLIE-VFPEDAAQYNCEAKNDYGVATS-SASLNVEVPEVVSPDTGAPLSPPVVLT 3123 Query: 114 PESKQSA-QGDTVVLECLPPRGSPEP-NVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDA 170 P SA +G + +C R S E + W + + R+ D L I Sbjct: 3124 PIQNTSANEGQSARFQC---RVSGEDLTITWYCKDKEIKQSDIFRVSQFDENCQLEITRV 3180 Query: 171 RQTDAGRYQCIARNAAGTRESAIATLKI 198 D G Y C+ARN+AG S A LK+ Sbjct: 3181 YPEDEGEYTCVARNSAG-MVSCSALLKV 3207 Score = 53.6 bits (123), Expect = 3e-05 Identities = 75/319 (23%), Positives = 125/319 (39%), Gaps = 36/319 (11%) Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV------FDGVTVLT 357 V +G + T TGRP P + W +G +D+ H V D +V+T Sbjct: 15595 VRAGTPFKIPATITGRPAPKVTWEFDGKAKT----EKKDRLHILPVDSQVESTDTTSVVT 15650 Query: 358 INDTDKNDS-RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416 + + ++ S R TI +A N +G V ++ V P + + T+ + + Sbjct: 15651 VPVSLRSHSGRYTI--TAKNKSGQKHVNVRVNVLDVPGAPKELKVTDVTRTTMRL----I 15704 Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVTN----DGTLVLKDLDKSDSGTYTCVASSR 472 + E I +++ E +A + V N V+ +L + + A +R Sbjct: 15705 WKLPDNDGGERIKSYFIEKKA-VNGKAWTVANATCASMAFVVSNLLEGQDYFFRVRAENR 15763 Query: 473 HGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGS 532 G P RA D P PPTK + VT +VTL+W G Sbjct: 15764 LGF----------GPFTETTEPVRARDPIYPPDPPTKVKINLVTKNTVTLTWVPPKNDGG 15813 Query: 533 SSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENS 592 + + Y +E S +T SG P+ R V +T ++++ L G Y F V+ N Sbjct: 15814 APVKHYIIERLSWDT-SG---PQKETWKQCNKRDVEETTFIIEDLKEGGEYEFRVKAVNE 15869 Query: 593 HGLSGPSPVSDSVTVGDDS 611 G S PS + + + D + Sbjct: 15870 AGASRPSVTAGPIVIKDQT 15888 Score = 53.6 bits (123), Expect = 3e-05 Identities = 81/315 (25%), Positives = 128/315 (40%), Gaps = 34/315 (10%) Query: 506 PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565 PP KP +VT +SV+L WS+ G S ++GY VE + NS + Sbjct: 18861 PPGKPEIIDVTKSSVSLVWSRPKHDGGSKLIGYYVEFLKLKEDKWVRVNSNS-------Q 18913 Query: 566 RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTE 625 V + Y+V L G Y F + + + +S PS SD + + + V S E Sbjct: 18914 NVPKEEYIVPGLEEGAQYKFRIIAKTAINVSVPSEESDVIPIIAEH----VPPRVEISLE 18969 Query: 626 YRNNILTDHIVEL-IEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTIL 684 +N I+ + +EA K++W+ +G PL + +M + Sbjct: 18970 MKNLIVVKAGANVCLEAEVYGKPMPKVVWK------KDG-----APL-KLAEGMKMTQKV 19017 Query: 685 HSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILN 744 H + F +T RK + + I K +N ++ + LD GPP ++ + + Sbjct: 19018 HHLSLELFSVT--RKESGE--YTITAENPSGSKSANIKL-KVLD--KPGPPASVRISHVF 19070 Query: 745 TTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGV 804 V L+W PP L IT Y +V AN + V N Q T + L G Sbjct: 19071 ADRVKLRWEPP-LADGGSEITNY-IVDKRETSRANWAQVTANIN-GQITDCSVEKLIEGH 19127 Query: 805 SYSVQIAAETIIGLG 819 Y +I+AE G+G Sbjct: 19128 EYEFRISAENKYGVG 19142 Score = 53.6 bits (123), Expect = 3e-05 Identities = 108/447 (24%), Positives = 177/447 (39%), Gaps = 58/447 (12%) Query: 178 YQCIARNAAGTRE-SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC----RVGGDPLPD 232 ++ A+N AG S + K+ I P G + + T SVT Q R GG + Sbjct: 27464 FRVYAQNNAGMSPVSEQSKHKLAISPVDPPGTPNCIDVTRDSVTLQWEPPKRDGGSRIVA 27523 Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVS----ASGYLT 288 R G + + + + D E+ A N+VG VS +SGY+ Sbjct: 27524 YSVERRQGRARWLRCNFIDVSECQFTVTGLAAGDRFEFRVIARNAVGTVSPPSQSSGYIM 27583 Query: 289 VYDP---PSINL-SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344 D P I + S+ +++G + +C+ +GRP P + W +G + + Sbjct: 27584 TKDESVIPQIEFEAEKSLTIKAGENIKLSCSISGRPVPQVTWYKDGKE------VDKMLV 27637 Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404 T V G + L I D D+N R A N +G++ V + V D PP GP Sbjct: 27638 DITTVI-GSSSLFIRDADRN-HRGIYTVEAKNSSGTTKV--DVLVRVQDTPGPP---EGP 27690 Query: 405 SNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH--RRNVTNDGTLVLKDLDKSDS 462 L +++ T +P +G A I N+ + T+ + L K ++ Sbjct: 27691 ----LRFTNISAEKATLWWSPPE-----NDGCAAISNYVIEKRETSRISWALV-TSKCEA 27740 Query: 463 GTYTCVASSRHGKYVWSGALL----VDSPINPN-IHFFRAADVSSLPGPPTKPITHNVTD 517 ++ + +Y + + + V P+ + I V PG P TH VT Sbjct: 27741 CSFNATKLIKGNEYQFRVSAVNKFGVGKPLESDPIIAQMQYTVPDAPGTP--DCTH-VTG 27797 Query: 518 TSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIA--RRVHQTHYVVK 575 S+TL W++ G + I Y +E RE + S WV ++ R + + + V Sbjct: 27798 NSITLCWTRPRHDGGNEIKQYILE--RRE--------KKSLRWVKVSAKRPITELRHRVT 27847 Query: 576 SLIPGITYMFIVRTENSHGLSGPSPVS 602 +L G Y F V EN G+ S +S Sbjct: 27848 NLTEGNEYEFRVMAENGAGIGPASGIS 27874 Score = 53.6 bits (123), Expect = 3e-05 Identities = 55/247 (22%), Positives = 91/247 (36%), Gaps = 31/247 (12%) Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN--HRRNV 446 +T D+ P I + T+ C+ P P + WY +G+ + + V Sbjct: 27583 MTKDESVIPQIEFEAEKSLTIKAGENIKLSCSISGRPVPQVTWYKDGKEVDKMLVDITTV 27642 Query: 447 TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGP 506 +L ++D D++ G YT A + SG VD + V PGP Sbjct: 27643 IGSSSLFIRDADRNHRGIYTVEAKNS------SGTTKVDVLVR----------VQDTPGP 27686 Query: 507 PTKPITH-NVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565 P P+ N++ TL WS G ++I Y +E RET + W ++ Sbjct: 27687 PEGPLRFTNISAEKATLWWSPPENDGCAAISNYVIE--KRET--------SRISWALVTS 27736 Query: 566 RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTE 625 + + LI G Y F V N G+ P+ + ++ + G + T Sbjct: 27737 KCEACSFNATKLIKGNEYQFRVSAVNKFGVG--KPLESDPIIAQMQYTVPDAPGTPDCTH 27794 Query: 626 YRNNILT 632 N +T Sbjct: 27795 VTGNSIT 27801 Score = 52.8 bits (121), Expect = 5e-05 Identities = 92/397 (23%), Positives = 159/397 (40%), Gaps = 55/397 (13%) Query: 425 PEPIIAWYFEGEALIQNHRRN--VTNDGTLV-LKDLDKSDSGTYTCVASSRHGKYVWSGA 481 P P ++ +G+ L R N VT D ++ L++ SD+G Y AS+ +G Sbjct: 26139 PLPKVSLSKDGQVLKSTMRFNFDVTTDSLIIYLRESVASDAGRYDITASNSNGT------ 26192 Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITH-NVTDTSVTLSWSQNNKIGSSSILGYQV 540 S +N V PGP P+ ++T+ SV+L W G S I Y V Sbjct: 26193 --TKSFVN--------VVVLDRPGPAVGPVEMCDITEDSVSLKWLPPAYDGGSPITNYIV 26242 Query: 541 EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600 RET + N W+ ++ V + + L G+ Y F ++ EN G+S Sbjct: 26243 --LKRETTTAN--------WIEVSSAVARCTIKIMKLNTGVEYQFRIKAENRFGISEHID 26292 Query: 601 VSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYY 660 S +VTV SL V+ S + + + + IV + D + + Sbjct: 26293 -SQTVTV-----SLPYTLPVAPSQPWVSAVTKESIVVNWKEPSSDGGS-----------H 26335 Query: 661 LEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN 720 + G + + ++I + T++ + + F++T++ YEF + G S Sbjct: 26336 VFGYHLQMKDRNSILWQKVNTTVIRA---THFKVTNVNAGLIYEFKVAAENAAGIGPISK 26392 Query: 721 SRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANK 780 S D + PP ++ + + ++ L W P ITGY ++ D P + Sbjct: 26393 SSDPVLAIDACE-PPNSVRVTDITKNSISLAWQKPSYD-GGSKITGY--LIEMKDGPKGR 26448 Query: 781 SMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817 A N T T ++ LT SY ++ A+ +G Sbjct: 26449 WSKA-NLTNVTDTKFTVSGLTQNESYEFRVMAKNAVG 26484 Score = 52.4 bits (120), Expect = 7e-05 Identities = 50/180 (27%), Positives = 74/180 (41%), Gaps = 24/180 (13%) Query: 134 GSPEPNVYWKKNGQTLLFDGD-SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192 G P+P V W NG+ + + + D +L+I ++ G Y C A N G + + Sbjct: 3429 GFPKPKVQWFHNGKAITSSSIYTFVEERDEYSLIITKVKKDYEGEYSCTASNRFG-QTTC 3487 Query: 193 IATLKIHIK-------------------PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233 LK+ + P T + V GS V FQ +V G P PDV Sbjct: 3488 KTILKVELSQLSAAEKWVEKMFKIPGQPPCFTTQIQPVQCVEGSEVKFQYKVTGTPFPDV 3547 Query: 234 LW-RRSAGGGNMPLGRVKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290 W + ++ + V DGS L + N+ D G Y+C+A N G S S L V+ Sbjct: 3548 QWFKGNSQIKSSQTCSVVCNPDGSGFLIMSNIQQRDSGLYTCKAVNPFGEASCSAELIVF 3607 Score = 52.4 bits (120), Expect = 7e-05 Identities = 36/103 (34%), Positives = 46/103 (44%), Gaps = 9/103 (8%) Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556 A D P PP THN T SVTL+W G S I+GY +E + + G + Sbjct: 14290 AEDQKQRPDPPVDVETHNPTSESVTLTWKPPMYDGGSKIMGYILE----KMMKGEENFQR 14345 Query: 557 SRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599 ++V Y VK L Y F VR EN+ G+S PS Sbjct: 14346 CNDFLVPV-----LSYTVKGLTHEKQYQFRVRAENAAGVSDPS 14383 Score = 52.4 bits (120), Expect = 7e-05 Identities = 77/319 (24%), Positives = 126/319 (39%), Gaps = 41/319 (12%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV- 562 PGPP P + T +S++LSW++ G ILGY VE F R ++ W+ Sbjct: 19260 PGPPAFPKVVDSTHSSISLSWTKPAYDGGCEILGYLVE-FKR---------ADAEEWMKC 19309 Query: 563 -IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVS 621 + + + T + V LI Y F V N G PS V + D + Sbjct: 19310 NVPKNLQATKFNVTGLIDNTEYQFRVSAVNKIGFGEPSEVPEKHLAKD----ILLAPEAE 19365 Query: 622 NSTEYRNNILTDHIVELIEATPIDSKTI-KLMWEILNFYYLEGLFIYFRPLDNITIEYEM 680 + R ++ V + P+ + K W +N E + + T E++ Sbjct: 19366 LDADLRKALVLRAGVTMRIYVPLRGRPAPKATWTKVNANLKERQGLMIK-----TTEWD- 19419 Query: 681 KTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEM 740 T L+ D++ ++ KY L + G S + V + LD GPP+N+ + Sbjct: 19420 -TFLYCEDINRYDA------GKYVLTL----ENSSGTKSYTIVVKVLD--TPGPPVNLIV 19466 Query: 741 FILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNL 800 + V + W P + G VV L K+ + + TS +TNL Sbjct: 19467 KETSKDHVSITWDAP--LIDGGSPVKSYVVEKRL--AERKAWTCVAPECPK-TSFRITNL 19521 Query: 801 TSGVSYSVQIAAETIIGLG 819 +G +Y ++ AE I G+G Sbjct: 19522 EAGQAYCFRVLAENIYGIG 19540 Score = 52.4 bits (120), Expect = 7e-05 Identities = 36/101 (35%), Positives = 47/101 (46%), Gaps = 14/101 (13%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 PGPP KP+ NVT +T+ W G S I GY +E RNS W+ + Sbjct: 27392 PGPPGKPVVFNVTSDGMTVQWDAPGFDGGSPITGYHLE----------KKDRNSLLWMKV 27441 Query: 564 ARRVHQ-THYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603 V Y V LI G+ Y F V +N+ G+ SPVS+ Sbjct: 27442 NTSVISGREYRVIGLIEGLEYSFRVYAQNNAGM---SPVSE 27479 Score = 52.4 bits (120), Expect = 7e-05 Identities = 33/109 (30%), Positives = 48/109 (44%), Gaps = 11/109 (10%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 PG P +P +VT S +SW G + I Y +E RE + W+ + Sbjct: 30458 PGVPQRPFVSSVTKDSCVVSWKPPTSDGGAKIKNYFLE--KRE--------KKQNKWIAV 30507 Query: 564 AR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDS 611 +H+T Y K L+ G Y F V+ EN G S S +S+ V D+ Sbjct: 30508 TTGEIHETSYTAKGLLEGFEYEFRVKCENIGGESDWSEISEPVIPKSDT 30556 Score = 52.0 bits (119), Expect = 1e-04 Identities = 36/111 (32%), Positives = 48/111 (43%), Gaps = 4/111 (3%) Query: 499 DVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558 D S+LPGPP K + T + L+W G S I GY +E RE G + Sbjct: 15367 DPSALPGPPEKVTIAERSKTHMLLTWEPPKDSGGSMITGYWLE--KRE--KGTSYWSRVN 15422 Query: 559 GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 +V R + Y V L G+ Y F NS G+ PS +S+S D Sbjct: 15423 KILVSKRGMKGWEYQVTRLFEGVEYEFRAMACNSAGIGPPSAISESAVADD 15473 Score = 52.0 bits (119), Expect = 1e-04 Identities = 36/130 (27%), Positives = 59/130 (45%), Gaps = 6/130 (4%) Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPS-NSRVAQTLDDV-PDGPPINIEMFILNTTTVH 749 + T L + +YE+ + + GKPS NS+ +D + P G P+N + T+V Sbjct: 29624 YRATGLIEGLEYEYRVTAINSRGTGKPSANSKPTIAMDPIEPPGIPLNPRVTDTTRTSVS 29683 Query: 750 LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQ 809 L WSPPE + +TGY + + +D NTT + +T++ G Y + Sbjct: 29684 LAWSPPE-EEGGAAVTGYLIEMQKVD---QVEWTKCNTTPTKICEYTLTHMPQGAEYKFR 29739 Query: 810 IAAETIIGLG 819 + A G G Sbjct: 29740 VMACNAGGAG 29749 Score = 51.6 bits (118), Expect = 1e-04 Identities = 47/173 (27%), Positives = 74/173 (42%), Gaps = 10/173 (5%) Query: 39 PSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG--TARS 96 P P++ W K G + D + + + H SD Y A N +G + ++ Sbjct: 31349 PEPSVTWLKAGHRIKPDPKKYTFTSDKGLYQLMIHNVDLSDDAEYTVVANNKFGEDSCKA 31408 Query: 97 R-NATLHVAV---LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFD 152 R N H +R F+ + +G +V + L G+P P + W+KNG+ L F Sbjct: 31409 RLNVAPHAVAEDTMRPMFKRLLANIDCVEGQSVRFD-LRVSGTPAPTLKWEKNGKPLEFR 31467 Query: 153 GDSRM--HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY 203 + VD L I++ D+G Y+ A N AG+ S ATLK+ Y Sbjct: 31468 PQVEVVQEDVDYFILHIRETLIEDSGTYRVTATNTAGS-ASCQATLKVERLTY 31519 Score = 51.2 bits (117), Expect = 2e-04 Identities = 39/156 (25%), Positives = 63/156 (40%), Gaps = 14/156 (8%) Query: 458 DKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSS---LPGPPTKPITHN 514 D +DS YT R KY++ PN+ +A + +P P I N Sbjct: 12857 DCADSTEYTVTGLQRDSKYLFRVCARNRVGSGPNVETDKAVQAKNKFDVPDAPQNVIVGN 12916 Query: 515 VTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV-VIARRVHQTHYV 573 V T+SW G S I Y +E+ R ++ W V+ + H+ + Sbjct: 12917 VNKFGATVSWEPPLFDGGSEITSYIIELRDRTSVV----------WAPVMVTKPHERSAI 12966 Query: 574 VKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 + +I Y+F V+ EN G+ PS ++ V + D Sbjct: 12967 INDVIENKEYIFRVKAENKAGIGKPSAATNPVKIMD 13002 Score = 51.2 bits (117), Expect = 2e-04 Identities = 135/628 (21%), Positives = 227/628 (36%), Gaps = 64/628 (10%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA-----THGR 75 + V +++P + G P P I W K V++ T + + + + + G Sbjct: 15178 IRVRKNEPIEMPAEVTGLPMPKIEWLKDDVVIEKPTEKLLFETKEIDRVTSHTKLSIPGV 15237 Query: 76 VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGS 135 D G Y A+N GT S + T+ V R S A+ + + G Sbjct: 15238 TRLDKGTYTVTASNRLGTL-SHSVTVEVLDRPTPPRNVAVSSIKAESCNLSWDAPLDIGG 15296 Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA----RQTDAGRYQ--CIARNAAGTR 189 E Y + + L + + V +I+ G Y+ A N G Sbjct: 15297 SELTNYIVEM-KDLNVEDPEKAEWVQVTKSIIEKRYGVWNLVTGGNYKFRVKAENKYGIS 15355 Query: 190 ESAIATLKIHIK-PYLITGPEDVVAQTGSSVTFQC------RVGGDPLPDVLWRRSAGGG 242 E A T ++ IK P + GP + V S T + G + W G Sbjct: 15356 E-ACETEEVEIKDPSALPGPPEKVTIAERSKTHMLLTWEPPKDSGGSMITGYWLEKREKG 15414 Query: 243 NMPLGRV-KVL------DDGSLRLDNVILADEGEYSCEAENS--VGAVSASGYLTVYD-- 291 RV K+L ++ + E E+ A NS +G SA V D Sbjct: 15415 TSYWSRVNKILVSKRGMKGWEYQVTRLFEGVEYEFRAMACNSAGIGPPSAISESAVADDP 15474 Query: 292 --PPSINLSPNSVNVESGNVA-RFTCTAT--GRPEPTMFWSVEGNRTIIFPGMS-RDKYH 345 PPS+ +P + +V +T A GRP ++ T + ++ + H Sbjct: 15475 LTPPSMPAAPEIADKTKHSVTLAWTPPAKDGGRPIKGYIIEIQDEGTSEWARVNDAENLH 15534 Query: 346 ATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD--RPPPIITNG 403 + VF T+ + + K R I+ AVN G S + + +D P I + Sbjct: 15535 PSTVF---TIPNLPELKKYRFR--II--AVNEIGESEPSPRTSEVRIEDIKTAPKIFMDI 15587 Query: 404 PSNQTLPIKSMAVF--PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSD 461 +++ L +++ F P T P P + W F+G+A + R ++ D + Sbjct: 15588 SADELLCVRAGTPFKIPATITGRPAPKVTWEFDGKAKTEKKDRLHILPVDSQVESTDTTS 15647 Query: 462 SGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVT 521 T S G+Y + + H +V +PG P + +VT T++ Sbjct: 15648 VVTVPVSLRSHSGRYT-----ITAKNKSGQKHVNVRVNVLDVPGAPKELKVTDVTRTTMR 15702 Query: 522 LSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGI 581 L W + G I Y +E ++ ++G + W V +VV +L+ G Sbjct: 15703 LIWKLPDNDGGERIKSYFIE---KKAVNG-------KAWTVANATCASMAFVVSNLLEGQ 15752 Query: 582 TYMFIVRTENSHGLSGPSPVSDSVTVGD 609 Y F VR EN G + ++ V D Sbjct: 15753 DYFFRVRAENRLGFGPFTETTEPVRARD 15780 Score = 51.2 bits (117), Expect = 2e-04 Identities = 75/296 (25%), Positives = 120/296 (40%), Gaps = 36/296 (12%) Query: 259 LDNVILADEGEYSCEAENSVG------AVSASGYLTVYDPPSINLSPN---SVNVESGNV 309 + N+ E E+ A+N VG A V++ P I+L + ++V +G Sbjct: 18234 ISNLDERQEYEFRVSAQNQVGMGRPANVKDAVSPKEVHEHPEIDLDASLRKGLSVRAGCP 18293 Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS-RN 368 R T GRP P + W G +I G H + D +T L I ++ + DS + Sbjct: 18294 IRLFATIRGRPAPKVTWKRIGVDNVIRRG------HVDQI-DTMTFLVIPESSREDSGKY 18346 Query: 369 TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428 ++ S + + FVR K+ D P P+ ++ T +A P PI Sbjct: 18347 SLTLSNPSGEKAVFVRVKVL-----DTPGPVGGLDATDITKTSCQLAWLP-PENDGGSPI 18400 Query: 429 IAWYFEGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485 + + E + + N TND + + +L + +A +++G L D Sbjct: 18401 LNYIVEKREVDRKTWTNCTNDLKKTSFKITNLTPGIEYYFRVMAVNKYGI-----GLPQD 18455 Query: 486 SPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541 SP + + A D S P PP K +T S TL W + + G S I GY VE Sbjct: 18456 SPKS-----YLATDPKSEPDPPKKMDVLEITKNSATLGWLKPLRDGGSKINGYIVE 18506 Score = 51.2 bits (117), Expect = 2e-04 Identities = 35/106 (33%), Positives = 51/106 (48%), Gaps = 10/106 (9%) Query: 506 PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565 PP++P+ N+T VTL W++ G SI GY VE RE +G N Sbjct: 20995 PPSQPVALNITRHEVTLQWTKPEGDGGFSITGYTVE--KRELPNGRWLKAN-------FS 21045 Query: 566 RVHQTHYVVKSLIPGITYMFIVRTENSHG-LSGPSPVSDSVTVGDD 610 + +T++ V L ++Y F V NS G +S PS S+ + DD Sbjct: 21046 NILETNFTVSGLTEDVSYEFRVLARNSAGAVSKPSKPSEVIVCRDD 21091 Score = 50.8 bits (116), Expect = 2e-04 Identities = 76/327 (23%), Positives = 130/327 (39%), Gaps = 50/327 (15%) Query: 499 DVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558 D++ PGPP+ P + T T+ T +W + G + GY VE + Sbjct: 20304 DIAYPPGPPSNPRITDTTKTTATFNWGRPFYDGGLDVTGYIVE----------HKKEGDD 20353 Query: 559 GWV---VIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLW 615 WV I R+ T +VV +L G Y F V NS GL PS V V + D Sbjct: 20354 DWVQDTTIPLRI--TEFVVSNLQSGGKYHFRVSALNSEGLGEPSEVEQVVELVDRE---- 20407 Query: 616 EGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNIT 675 E E R ++ + PI + E++ +Y E + PL Sbjct: 20408 EVPDFELDAELRKTLVVKSGASIRIFVPIKGRPAP---EVV--WYKENV-----PL---- 20453 Query: 676 IEYEMKTILHSNDVSGFEITSLRKYTKYEF-FLIPFYKKFEGKPSNSRVAQTLDDVPDGP 734 K H + + + + + T+Y+ + + GK + V + D P GP Sbjct: 20454 -----KGRAHIDTTESYTLVVIPECTRYDAGKYVLTLENVAGKKTGF-VNVRVVDTP-GP 20506 Query: 735 PINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWL--DVPANKSMVAINTTVHQA 792 P+N++ + ++ L+W P +I G + + N++ A + ++ TT Q Sbjct: 20507 PVNLKPREITKHSITLQWEIP-------LIDGGSKIKNYIIEKREATRKAYSVITTNWQK 20559 Query: 793 TSLIMTNLTSGVSYSVQIAAETIIGLG 819 S + +L Y +++AE +G+G Sbjct: 20560 CSYKIPDLEEAAEYYFRVSAENEMGIG 20586 Score = 50.4 bits (115), Expect = 3e-04 Identities = 38/137 (27%), Positives = 54/137 (39%), Gaps = 7/137 (5%) Query: 196 LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255 L + P L +D + G S C++ G PLP++ W R G + + K+ DG Sbjct: 30160 LSVGEAPCLKEDIKDTTTKLGESGILTCQIIGRPLPEIKWYRY-GKELIQSRKYKMSSDG 30218 Query: 256 ---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS---PNSVNVESGNV 309 SL + DEG Y+C A N G + SG L + P + G Sbjct: 30219 RNHSLSVMTDEQEDEGLYTCRAVNEAGEIETSGKLLLQAAPQFHPGFPLKEKYYAGCGTS 30278 Query: 310 ARFTCTATGRPEPTMFW 326 R GRP P + W Sbjct: 30279 LRLHVVYIGRPIPQIMW 30295 Score = 50.0 bits (114), Expect = 4e-04 Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 2/92 (2%) Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL 259 + P LI G ++V G SVT +C++ G P P ++W R + + RL Sbjct: 740 VPPTLIAGLKNVTVTEGESVTLECQISGHPTPAIMWFREDYRIENSIDFQITYEKSYARL 799 Query: 260 --DNVILADEGEYSCEAENSVGAVSASGYLTV 289 D G ++C A + G +S S YL V Sbjct: 800 MIREAFAEDSGRFTCTATSEAGTISTSCYLLV 831 Score = 50.0 bits (114), Expect = 4e-04 Identities = 48/154 (31%), Positives = 62/154 (40%), Gaps = 7/154 (4%) Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGL 66 S EAP I+E+ TVA CR G P P +W+K G+L+ SD P + Sbjct: 1847 SMEAPKILERIQSQTVALADEVRFRCRVIGKPDPECQWFKNGILLEKSDRVYWYWPEDHV 1906 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126 L + D+ +A N G A S L A F E + + DT+V Sbjct: 1907 CEL-VIRDVLAEDSASIMVKAINIAGEASSHAFLLVQAKQVVSFTQTLEDAYAKEKDTMV 1965 Query: 127 -LECLPPRGSPEPNVYWKKNGQTLLFDGDS-RMH 158 EC P V W KN +F GD RMH Sbjct: 1966 TFEC--ETNEPFVKVKWMKNNAE-IFSGDKYRMH 1996 Score = 49.6 bits (113), Expect = 5e-04 Identities = 48/193 (24%), Positives = 72/193 (37%), Gaps = 14/193 (7%) Query: 289 VYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348 +Y P + P+S G ARF GRP P FW G + + D H Sbjct: 1226 LYKPVFVQ-KPSSFRCSEGQTARFDLKVVGRPMPDTFWFHSGQQVV------NDYTHKIV 1278 Query: 349 V-FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407 V DG + + DS V A N AG + V LTV + ++ P N Sbjct: 1279 VKEDGTQSMIVVPAMPQDSGEWTVV-AQNRAGKTTVSMTLTVEAKENLVRPQFIEKLKNI 1337 Query: 408 TLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-----LVLKDLDKSDS 462 ++ S+ AI P P I W + + + ++ +G + SDS Sbjct: 1338 SVKEGSLVELAVKAIGNPLPDIVWLKNSDIISPHKYPHIKIEGAKGQAHFQIPQTSGSDS 1397 Query: 463 GTYTCVASSRHGK 475 YT A ++ G+ Sbjct: 1398 AWYTATAINKAGR 1410 Score = 49.2 bits (112), Expect = 7e-04 Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 4/106 (3%) Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249 E ++ +K + ++T P ++ G S F C + G+P P V W G + R+ Sbjct: 32125 EVSVKKIKATLSAKILTKPHSLIVSEGDSARFVCDIDGEPAPTVTWMHE-GRTVVSSHRI 32183 Query: 250 KVLD---DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292 V +L + +V +DEG Y+ ENS G A L + P Sbjct: 32184 HVSTTQYKSTLEISSVEYSDEGNYTVVVENSEGKQEARCTLAINKP 32229 Score = 48.8 bits (111), Expect = 9e-04 Identities = 35/110 (31%), Positives = 46/110 (41%), Gaps = 11/110 (10%) Query: 500 VSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRG 559 ++ P PP K +VT SV+L+W + G S I Y VE + + Sbjct: 26006 ITEKPSPPPKLGVTDVTKESVSLAWLKPEHDGGSRITNYLVEALE----------KGQQK 26055 Query: 560 WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 W+ TH+VV L Y F VR EN GLS P + V V D Sbjct: 26056 WIKCG-STKSTHFVVDGLRENAEYYFRVRAENHAGLSDPKDMVLPVLVKD 26104 Score = 48.0 bits (109), Expect = 0.002 Identities = 50/197 (25%), Positives = 76/197 (38%), Gaps = 14/197 (7%) Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGN--RTIIFPGMSRDKYHATAVF 350 P+ SV G+ A F +G P P + W +G PG + Sbjct: 6 PTFTQPLQSVVALEGSAATFEAQVSGNPVPEVSWFRDGQVLTAAALPGAQ------ISFS 59 Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410 DG VL I S V A N AG + +L VT++ PP + T+ Sbjct: 60 DGRAVLMIPAVTAAHSGRFSV-RATNGAGQATSTAELLVTAET--APPNFIQRLQSLTVR 116 Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTC 467 S P P++ +Y EG + + + DG +L++ + DSGTY+ Sbjct: 117 QGSQVRLDVRVTGIPAPVVKFYREGAEIQSSADFQIVQDGDLYSLLIAEAFPEDSGTYSV 176 Query: 468 VASSRHGKYVWSGALLV 484 AS+ G+ + LLV Sbjct: 177 SASNSSGRATSTAELLV 193 Score = 48.0 bits (109), Expect = 0.002 Identities = 104/491 (21%), Positives = 183/491 (37%), Gaps = 67/491 (13%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 V GE PY + D T L C S S ++W+K G ++ + ++ A G Sbjct: 11713 VLEGE-PYFTTKLQDYTAVEKDEVVLMCEVSKS-SAQVKWFKDGN-EITPSKNVLIKADG 11769 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 + + G Y C+ + A+ + ++R + +E ++A+ +T Sbjct: 11770 KKRILTVKKAEKGNIGEYVCDCGSDKTAAKLNIEERDIKIVRPLYSVEVTETETARFETE 11829 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLL-----------FDGDSRM---HLVDGGN---LVIQ 168 + E + + +WK G L + + M + + G L++ Sbjct: 11830 ISE-------EDVHGHWKLKGDALHQSPVISFTPKHYFSITMMKDCEIKEEGTKHMLILY 11882 Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228 + R AG A NA + + I L+ +DV G + TF C + + Sbjct: 11883 NVRMDMAGAVDFSAANAKSKAQLRVKARVIG----LLRPLKDVTVTAGETATFDCELSYE 11938 Query: 229 PLPDVLWRRSAGGGNM-PLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSAS 284 +P V W GG + P RV +G +L L +V L + GE A++ + Sbjct: 11939 GIP-VEW--FLGGTKLEPSDRVVTRAEGRSHTLTLRDVKLTEAGEVKLTAKDFL----TQ 11991 Query: 285 GYLTVYDPPSINLSP-NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDK 343 L V +PP P VE A C + + + + W +G K Sbjct: 11992 AQLIVNEPPVEFTKPLEDQTVEEEATAELECEVS-KEKAEVRWFRDGQEI-----RKTKK 12045 Query: 344 YHATAVFDGV-TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN 402 Y A DG L I+D +DS+ T C A ++ S+F+ + PP + Sbjct: 12046 YDMVA--DGCKRKLVIHDCTLDDSK-TYTCDAKHFKTSAFL---------NVEPPYVEFT 12093 Query: 403 GPSNQT-LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS- 460 P + + K A F C + + W+ +G + + + + ++G + + KS Sbjct: 12094 KPLHDVEVKEKESARFEC-EVSRESAKVRWFRDGNEIRKGKKYEMISEGVKRILIISKSV 12152 Query: 461 --DSGTYTCVA 469 D Y C A Sbjct: 12153 FDDEAEYECDA 12163 Score = 48.0 bits (109), Expect = 0.002 Identities = 61/242 (25%), Positives = 95/242 (39%), Gaps = 32/242 (13%) Query: 374 AVNYAGSSFVRGKLTVTSDDDR--PPPIITNGPSNQTLPIKSMAVFPCTAICT--PEPII 429 AVN AG V DR PP + + + + + + V A + P P I Sbjct: 16165 AVNAAGVGEPGEVADVIEVKDRTIPPEVDLDATVKEKIVVHAGGVIRILAYVSGKPAPEI 16224 Query: 430 AWYFEGEALIQNHRRNVTN-DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPI 488 W + L + T+ LV+K + G YT A + G+ A++V+ Sbjct: 16225 IWNRDDAELPKEAAVETTSISSALVIKSCLRQHQGIYTLTAKNAGGER--KKAVIVE--- 16279 Query: 489 NPNIHFFRAADVSSLPGPPTKPIT-HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRET 547 V +PGP P + N+T+ S L+W G S+I Y +E RE Sbjct: 16280 -----------VLDVPGPVGLPFSGENLTNDSCKLTWYSPEDDGGSAITNYIIE--KREA 16326 Query: 548 LSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607 + RGW + V + + VV+ LI G Y F + EN G+ + + V + Sbjct: 16327 --------DRRGWTSVTYTVTRHNAVVQGLIDGKGYFFRIAAENIIGMGPFTETAAPVVI 16378 Query: 608 GD 609 D Sbjct: 16379 KD 16380 Score = 48.0 bits (109), Expect = 0.002 Identities = 31/107 (28%), Positives = 45/107 (42%), Gaps = 11/107 (10%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 PGPP P + +T+ W+ G SI GY +E + + WV + Sbjct: 18061 PGPPDAPEVTKIGKDEMTVVWAPPENDGGKSITGYILERKEKRAVR----------WVPV 18110 Query: 564 ARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 + + + V +LIP Y F V+ EN GL PS S +T D Sbjct: 18111 TKSPISERRMKVTNLIPNHDYQFRVKAENEVGLGEPSKASRPITAKD 18157 Score = 47.6 bits (108), Expect = 0.002 Identities = 47/175 (26%), Positives = 68/175 (38%), Gaps = 29/175 (16%) Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTL---VLKDLDKSDSGTYTCVASSRHGKYVWSGA 481 P P + W +G +L Q R NV TL +KD + D+G Y ++ G V S Sbjct: 25057 PSPEVTWKKDGHSLKQTTRVNVLTSKTLSKITIKDATREDAGKYEITLTNTFG--VKSAE 25114 Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541 + V V PGPP ++ ++LSW G I Y VE Sbjct: 25115 ISVI--------------VLDKPGPPGAIKVEEISADFISLSWDPPIYDGGCQINNYVVE 25160 Query: 542 VFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596 R+T + W +++ V +T V L G Y F + EN +G S Sbjct: 25161 --KRDT--------TTTAWQIVSATVARTSIKVSRLTQGTEYQFRIAAENRYGKS 25205 Score = 47.6 bits (108), Expect = 0.002 Identities = 36/106 (33%), Positives = 53/106 (50%), Gaps = 10/106 (9%) Query: 506 PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565 PP++P N+T TSV+LSW++ G + + GY VE R L + R Sbjct: 25322 PPSQPRVMNITRTSVSLSWTKPEFDGGAKVTGYIVE---RSELP------DGRWLKCNFT 25372 Query: 566 RVHQTHYVVKSLIPGITYMFIVRTENSHGL-SGPSPVSDSVTVGDD 610 + +T++ V LI Y F + +N+ GL S PS + VTV DD Sbjct: 25373 NLQETYFDVTGLIEDQRYDFRIIAKNAAGLFSEPSESTGPVTVKDD 25418 Score = 47.6 bits (108), Expect = 0.002 Identities = 103/495 (20%), Positives = 195/495 (39%), Gaps = 57/495 (11%) Query: 134 GSPEPNVYW--KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG-TRE 190 G + YW KK T+L+ ++++ V+ + + + +++ A N AG ++ Sbjct: 28500 GGSQVTGYWIEKKERNTILWVRENKIPCVEC-HYKVSTLIEGLEYQFRVYAMNIAGLSKA 28558 Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV----GGDPLPDVLWRRSAGGGNMPL 246 S + + + P G +V T +SV+ + V GG + + R A + Sbjct: 28559 SEPSRPVLALNPVDPPGTPEVYDVTKTSVSIRWSVPFNDGGSKIVGYVVERKASSDDEEA 28618 Query: 247 GRVK----VLDDGSLRLDNVILADEGEYSCEAENSVGAVS----ASGYLTV---YDPPSI 295 +K + + + +++ ++ E+ A N G S +SG +T Y PP Sbjct: 28619 RWLKCNYTTITENFFTVTSLVEGEQYEFRVIARNGAGVHSMPSASSGLITCKDEYTPPKA 28678 Query: 296 NLSPN----SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 L ++++ +G+ G+PEP +FW+ +G++ + PG +KY T Sbjct: 28679 ELDSKLVGETISIRAGSDLVLDAAVGGKPEPKVFWA-KGDKE-LDPG---EKYSLTYTST 28733 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411 + I D+ND+ I+ + N +G + V + T GP T+ I Sbjct: 28734 RAMAI-IKSCDRNDTGRYIL-TVKNASGIKTSAVNVKV---------LDTPGPPAGTITI 28782 Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471 + CT + P+ I RR + +++ +++ T +CV++ Sbjct: 28783 SRVTDEKCT-VSWKIPLEDGGDHVSHYIV-ERRETSRLNWVIM----ETECKTLSCVSTK 28836 Query: 472 --RHGKYVW--SGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527 ++ +Y++ G + A + ++P PP P + V + W + Sbjct: 28837 LIKNNEYIFRVRGVNKYGPGVPLESEPVIARNAYTVPTPPGTPDITAIGKEHVIIEWFKP 28896 Query: 528 NKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIV 587 G S I Y V+ RE S T N ++ T + L+ G Y F V Sbjct: 28897 ENDGGSEIKNYLVD--KREKSSVRWTRVNK------TYTIYDTRLKITGLLEGSDYQFRV 28948 Query: 588 RTENSHGLSGPSPVS 602 N+ G S PS S Sbjct: 28949 SAVNAAGTSAPSDAS 28963 Score = 47.6 bits (108), Expect = 0.002 Identities = 53/220 (24%), Positives = 84/220 (38%), Gaps = 17/220 (7%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DG---SL 257 P+ D+ + ++ TF +V G P P V W ++ ++KV + G L Sbjct: 30561 PFFKDELRDMCVKYKANATFVTKVVGHPKPVVKWYKNGKEILADGAKIKVQEFKGGYFQL 30620 Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL-----SPNSVNVESGNVARF 312 + N D Y A N +G++S S L V P I L +V+ G V Sbjct: 30621 VISNADENDAAAYQIRATNQLGSISTSMNLDVEVPAKIYLPLHLQGMGAVHAIRGEVVTI 30680 Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT-INDTDKNDSRNTIV 371 +G+P+P + W +G I + YH + T L + + DS I+ Sbjct: 30681 KIPISGKPDPVVTWQ-KGQEII-----NNTAYHQVIITRSFTSLVFLKGVQRKDSGYYII 30734 Query: 372 CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411 C A N G +L V D P + + TL + Sbjct: 30735 C-AKNRFGMDKQTVELDVADVPDPPKDVKVSDIGRDTLTL 30773 Score = 47.2 bits (107), Expect = 0.003 Identities = 45/156 (28%), Positives = 65/156 (41%), Gaps = 18/156 (11%) Query: 457 LDKSDSGTYTCVA-SSRH--GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITH 513 +D+ D+ T+ + SSR GKY +L + +P F R V PGP Sbjct: 18324 VDQIDTMTFLVIPESSREDSGKY----SLTLSNPSGEKAVFVRVK-VLDTPGPVGGLDAT 18378 Query: 514 NVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYV 573 ++T TS L+W G S IL Y VE RE + + W + +T + Sbjct: 18379 DITKTSCQLAWLPPENDGGSPILNYIVE--KREV--------DRKTWTNCTNDLKKTSFK 18428 Query: 574 VKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 + +L PGI Y F V N +G+ P S D Sbjct: 18429 ITNLTPGIEYYFRVMAVNKYGIGLPQDSPKSYLATD 18464 Score = 47.2 bits (107), Expect = 0.003 Identities = 27/85 (31%), Positives = 44/85 (51%), Gaps = 2/85 (2%) Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR--VKVLDDGSLRLDNVILADEG 268 +V + G++V + V G P+P V+W++ + G + + SL L +V + G Sbjct: 18974 IVVKAGANVCLEAEVYGKPMPKVVWKKDGAPLKLAEGMKMTQKVHHLSLELFSVTRKESG 19033 Query: 269 EYSCEAENSVGAVSASGYLTVYDPP 293 EY+ AEN G+ SA+ L V D P Sbjct: 19034 EYTITAENPSGSKSANIKLKVLDKP 19058 Score = 47.2 bits (107), Expect = 0.003 Identities = 38/108 (35%), Positives = 46/108 (42%), Gaps = 11/108 (10%) Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562 +PGP P+ NVT +T++W G ++ILGY VE RET N WV Sbjct: 19158 VPGPCEPPVITNVTRDHMTVTWKAPANDGKATILGYMVE--KRETQDLN--------WVK 19207 Query: 563 IARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 + RR V L G Y F V N GL PS S V D Sbjct: 19208 VNRRPVIDRTIKAGGLTEGTEYEFRVIALNKAGLGKPSDPSSGVLALD 19255 Score = 47.2 bits (107), Expect = 0.003 Identities = 36/128 (28%), Positives = 53/128 (41%), Gaps = 13/128 (10%) Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543 V +P P+ +++A D + PGPP P + + T+V+L+WS+ G + + GY VE Sbjct: 24619 VGTPSEPS-EYYKACDATYPPGPPNNPKVTDHSSTTVSLAWSRPIYDGGAPVSGYIVEA- 24676 Query: 544 SRETLSGNNTPRNSRGWVVIA--RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPV 601 N W V V TH+ VK L Y F + N G V Sbjct: 24677 ---------KDINEDEWTVCTPPTGVQATHFTVKKLKENAEYNFRICAVNIEGAGEHVDV 24727 Query: 602 SDSVTVGD 609 SV + Sbjct: 24728 PGSVIAAE 24735 Score = 47.2 bits (107), Expect = 0.003 Identities = 33/113 (29%), Positives = 46/113 (40%), Gaps = 11/113 (9%) Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556 A +S P PP K +VT +VTLSW + + G S I GY VE+ + + Sbjct: 24924 AVKISQAPLPPGKITVIDVTRHTVTLSWEKPDHDGGSKITGYMVEMMT----------KG 24973 Query: 557 SRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 S W + ++ L G Y F + N G S P P+ V D Sbjct: 24974 SDKWTACV-TIKALEATIEGLTTGEEYSFRITAINDKGKSDPKPLGAPVVARD 25025 Score = 47.2 bits (107), Expect = 0.003 Identities = 42/155 (27%), Positives = 71/155 (45%), Gaps = 14/155 (9%) Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC---- 129 G V + + +A N G ++ R+A V + +E R+EP + S+ D ++ C Sbjct: 28239 GLVENTEYEFRVKAQNDAGISQPRDALASVII--KEPRIEPTADLSSI-DKQLITCKTGN 28295 Query: 130 -----LPPRGSPEPNVYWKKNGQTLL-FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183 +P G P P V WK L D S D L+++DA++ D+G+Y Sbjct: 28296 SFAIDIPISGRPAPKVTWKLEEMKLKETDRVSIKISKDRTTLLVKDAKRGDSGKYYLTLE 28355 Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSS 218 NAAG++ + + I +P TGP ++ + S Sbjct: 28356 NAAGSKTFTVTVIVIG-RPTPPTGPVEISGVSSES 28389 Score = 47.2 bits (107), Expect = 0.003 Identities = 45/167 (26%), Positives = 67/167 (40%), Gaps = 14/167 (8%) Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGTRESAI 193 PEP+V W K G + D D G L+I + +D Y +A N G +S Sbjct: 31349 PEPSVTWLKAGHRIKPDPKKYTFTSDKGLYQLMIHNVDLSDDAEYTVVANNKFG-EDSCK 31407 Query: 194 ATLKI--H------IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM- 244 A L + H ++P ++ G SV F RV G P P + W ++ Sbjct: 31408 ARLNVAPHAVAEDTMRPMFKRLLANIDCVEGQSVRFDLRVSGTPAPTLKWEKNGKPLEFR 31467 Query: 245 PLGRV--KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 P V + +D L + ++ D G Y A N+ G+ S L V Sbjct: 31468 PQVEVVQEDVDYFILHIRETLIEDSGTYRVTATNTAGSASCQATLKV 31514 Score = 46.8 bits (106), Expect = 0.004 Identities = 37/116 (31%), Positives = 48/116 (41%), Gaps = 13/116 (11%) Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE---VFSRETLSGNNT 553 A D +P PP P+ + T SVTLSW G I GY +E E L N T Sbjct: 16775 AKDPIVIPSPPVLPVAIDKTKESVTLSWQPPKDCGRGKIFGYLLEYQKAGDEEWLQVNQT 16834 Query: 554 PRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 P + T + V +L G Y F V+ N+ G S P+ V + V D Sbjct: 16835 PDS----------CPSTTFKVINLEDGALYRFRVKAVNAAGESEPAYVPEPVRAQD 16880 Score = 46.8 bits (106), Expect = 0.004 Identities = 36/107 (33%), Positives = 51/107 (47%), Gaps = 9/107 (8%) Query: 506 PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI-A 564 PP P ++VT TSV++ WS G S I+GY VE R+ S + R W+ Sbjct: 28573 PPGTPEVYDVTKTSVSIRWSVPFNDGGSKIVGYVVE---RKASSDDEEAR----WLKCNY 28625 Query: 565 RRVHQTHYVVKSLIPGITYMFIVRTENSHGL-SGPSPVSDSVTVGDD 610 + + + V SL+ G Y F V N G+ S PS S +T D+ Sbjct: 28626 TTITENFFTVTSLVEGEQYEFRVIARNGAGVHSMPSASSGLITCKDE 28672 Score = 46.8 bits (106), Expect = 0.004 Identities = 73/305 (23%), Positives = 117/305 (38%), Gaps = 40/305 (13%) Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361 VNV +G GRP P WS G + + + R K TA F T LT+ +T Sbjct: 29380 VNVPAGKPIVLNIPIKGRPAPVCSWSFGGVK--MKDKLDRIKIETTAKF---TKLTVRET 29434 Query: 362 DKNDSRN-TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420 +D+ + T+ V+ + +R II + P P+K V + Sbjct: 29435 TIDDTGDYTLNVKNVSGTATEVIR-------------VIILDKPGVPVGPMKIEEVDATS 29481 Query: 421 AICTPEPIIAWYFEGEALIQNH---RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477 C+ EP +G A + + +R+ G + + + +T + +YV Sbjct: 29482 VTCSWEPPQK---DGGANVSGYIVEQRDAHRPGWMSVSESVTRPVFKFTRLVEGT--EYV 29536 Query: 478 WSGALLVDSPINPNIH--FFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSI 535 + A I + V ++PG P+ P +V+ +TL+W+ G S+I Sbjct: 29537 FRVAATNRFGIGGFLQSEVVECKSVKTVPGAPSTPEILDVSHDGMTLTWTPPEDNGGSTI 29596 Query: 536 LGYQVEVFSRETLSGNNTPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMFIVRTENSHG 594 GY +E S W+ I + V T Y LI G+ Y + V NS G Sbjct: 29597 AGYIIE----------RKEAGSDRWLSINKNPVTMTRYRATGLIEGLEYEYRVTAINSRG 29646 Query: 595 LSGPS 599 PS Sbjct: 29647 TGKPS 29651 Score = 46.4 bits (105), Expect = 0.005 Identities = 71/305 (23%), Positives = 111/305 (36%), Gaps = 21/305 (6%) Query: 10 EAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68 EAP L D T+ + A +C + I+WY+ G + G Sbjct: 12536 EAPTDFTAQLSDQTITEFEDAEFSCELTKEKAD-IKWYRDGREIREGPRYQFERDGKTCR 12594 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128 LR R + CE R+R A L V E P G VV E Sbjct: 12595 LRIKECRPDDE-----CEYACGVDDKRTR-ARLFVEETPVEIVRPPTDVFEPPGSDVVYE 12648 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAA 186 + E V W +N T++ GD + +G L + + R D G Y+ IA++ Sbjct: 12649 VELNKDRVE--VKWLRNNMTIV-QGDKYQMMSEGKIHRLQVCEIRPRDQGEYRVIAKD-- 12703 Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 + A A L++ P + T +D+V G PL + W + ++P Sbjct: 12704 ---KDARAKLELAAVPTIKTLDQDLVTDAGKPFVMGVPYNAYPLAEAEWFYN--DISLPK 12758 Query: 247 GRVKV-LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305 + +D RL + ++EG Y +N G A L V D P + V+ Sbjct: 12759 DNIHTSIDRTEYRLKDPKKSEEGRYKIIVQNKHGKGEAFINLKVIDVPGPVKNLQVVDTA 12818 Query: 306 SGNVA 310 G ++ Sbjct: 12819 DGEIS 12823 Score = 46.4 bits (105), Expect = 0.005 Identities = 82/359 (22%), Positives = 139/359 (38%), Gaps = 42/359 (11%) Query: 259 LDNVILADEGEYSCEAENSVGAVS---ASGYLTVYDP---PSINLSP---NSVNVESGNV 309 L+ ++ E E+ +A+N G A + + +P P+ +LS + ++GN Sbjct: 28237 LEGLVENTEYEFRVKAQNDAGISQPRDALASVIIKEPRIEPTADLSSIDKQLITCKTGNS 28296 Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369 +GRP P + W +E + D+ D T+L + D + DS Sbjct: 28297 FAIDIPISGRPAPKVTWKLEEMKL-----KETDRVSIKISKDRTTLL-VKDAKRGDSGKY 28350 Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPP-PIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428 + + N AGS + V P P+ +G S+++ + I Sbjct: 28351 YL-TLENAAGSKTFTVTVIVIGRPTPPTGPVEISGVSSESCVLTWGEPSDDGGTDITNYI 28409 Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG--KYVWSGALLVDS 486 + G Q +V T+ + L K T+ A ++ G K + S A++ + Sbjct: 28410 VEKRESGSTTWQVVNSSVKRT-TIKVTHLTKYMEYTFRVSAENKFGVSKSIESQAIVAEH 28468 Query: 487 PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRE 546 P +S P PPT+P +V ++++ W G S + GY +E R Sbjct: 28469 PF-----------IS--PSPPTRPDVVSVCANAISIRWDVPYHDGGSQVTGYWIEKKERN 28515 Query: 547 TLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605 T+ R ++ V + HY V +LI G+ Y F V N GLS S S V Sbjct: 28516 TILW---VRENKIPCV------ECHYKVSTLIEGLEYQFRVYAMNIAGLSKASEPSRPV 28565 Score = 46.4 bits (105), Expect = 0.005 Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 3/77 (3%) Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN---DGTLVLKDLDKSDSGTYTCVASS 471 A F C P P + W EG ++ +HR +V+ TL + ++ SD G YT V + Sbjct: 32154 ARFVCDIDGEPAPTVTWMHEGRTVVSSHRIHVSTTQYKSTLEISSVEYSDEGNYTVVVEN 32213 Query: 472 RHGKYVWSGALLVDSPI 488 GK L ++ PI Sbjct: 32214 SEGKQEARCTLAINKPI 32230 Score = 46.0 bits (104), Expect = 0.006 Identities = 38/135 (28%), Positives = 53/135 (39%), Gaps = 12/135 (8%) Query: 494 FFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNT 553 F++A D P PTK + T TS+TL W + G S I Y +E Sbjct: 26792 FYKAYDPIDPPSEPTKLRVVDSTKTSITLGWVKPVYDGGSEITSYVIE----------QR 26841 Query: 554 PRNSRGWVVIARR--VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDS 611 + WV I+ + V T +VV L PG+ Y + V N G + V D Sbjct: 26842 IADETEWVTISSKGEVRTTEFVVSHLKPGVYYYYRVSAVNCVGTGRSIEIVQPVQAKDIL 26901 Query: 612 NSLWEGTGVSNSTEY 626 +S ST+Y Sbjct: 26902 EEADVDLDISMSTQY 26916 Score = 45.2 bits (102), Expect = 0.011 Identities = 80/311 (25%), Positives = 124/311 (39%), Gaps = 40/311 (12%) Query: 15 IEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRS--ILPAGGLFFLR 70 I +PL DVTVA Q A + C +P+ +W K G V SD RS I L F+ Sbjct: 2395 INRPLHDVTVAESQTAVMECEV-ANPTSEGKWLKDGHSVDFSDIVRSEDIDAVRRLIFVI 2453 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC- 129 D G Y + NS +A L V ++ + L+ ++ Q LE Sbjct: 2454 TR----PQDIGEYTYQVANS-----KTSANLRVEAVKIKKTLKNQTVTETQEAVFSLELT 2504 Query: 130 -LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAA 186 L +GS W KNG + D VDG L I++ D Y + Sbjct: 2505 HLDVKGS-----QWIKNG-VEIEPSDKYEITVDGLVHTLKIKNCNSQDESVYGFKLGKLS 2558 Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 + T+KI + P+DV + + +F+ + D +P V W P Sbjct: 2559 ANARLNVETIKI------VKKPKDVTSLVNGTASFELSLSHDDIP-VKW-MFKNQELKPS 2610 Query: 247 GRVKVLDD---GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303 V+++ + L + NV +++GEY+ VG + S YL V + + ++ Sbjct: 2611 ANVQIMSERKAHKLVIQNVEESNDGEYTA----VVGHLQCSAYLHV-ESLRVTKPLKNLE 2665 Query: 304 VESGNVARFTC 314 V +VA F C Sbjct: 2666 VPETHVATFEC 2676 Score = 45.2 bits (102), Expect = 0.011 Identities = 54/223 (24%), Positives = 90/223 (40%), Gaps = 26/223 (11%) Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRW----YKGGV----------LV 52 T AP +I+ PL V +P + A + S ++ W Y GG L+ Sbjct: 16370 TETAAPVVIKDPLSVP---ERPEDVEVTAITNDSISVAWRSPKYDGGSDITSYVLEVRLI 16426 Query: 53 VSDTHRSILPAGGLFFLRATH-GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE--- 108 D I L + TH G + + A N G + +T V +E Sbjct: 16427 GQDNFSRIAKEDKLMDRKFTHAGLKEGSSYEFRVSAVNQIGQGKPSFSTKPVTCKKEFEP 16486 Query: 109 -EFRLEPESKQSAQ-GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NL 165 LE K + G+T +++ G PEP + W KN + L + + + +L Sbjct: 16487 PNLDLEFRDKLVVRVGETCIIQSRYT-GKPEPTIKWFKNDEELQANEEIALTTAKNRLSL 16545 Query: 166 VIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208 I+ A++ +G+Y + N+ GTR+ I T+ + +P GP Sbjct: 16546 TIEKAKRDHSGKYMVVLENSIGTRK-GICTVNVVDRPQPPEGP 16587 Score = 45.2 bits (102), Expect = 0.011 Identities = 20/53 (37%), Positives = 31/53 (58%) Query: 489 NPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541 +P+ F++A D PGPP P + T +S+T++W++ G S I GY VE Sbjct: 21377 SPSSPFYKACDTIFQPGPPGNPRVLDTTKSSITIAWNKPVYDGGSDITGYIVE 21429 Score = 45.2 bits (102), Expect = 0.011 Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 6/90 (6%) Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIARNAAGTRE 190 G P+P + W K+G L +R+++ D + L I+DA + D G Y + N G +E Sbjct: 22890 GHPKPTITWNKDGSAL--KQTTRVNVADTAHHTTLTIKDATREDGGMYNIVVANVLGQQE 22947 Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVT 220 + + + + KP TGP + + S+T Sbjct: 22948 ATVEIIILE-KPGPPTGPVRIDEVSAESIT 22976 Score = 44.8 bits (101), Expect = 0.015 Identities = 57/220 (25%), Positives = 95/220 (43%), Gaps = 18/220 (8%) Query: 17 QPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL--RAT- 72 QPL VA AT + G+P P + W++ G ++ + + LP + F RA Sbjct: 10 QPLQSVVALEGSAATFEAQVSGNPVPEVSWFRDGQVLTA----AALPGAQISFSDGRAVL 65 Query: 73 --HGRVHSDAGVYWCEATNSYGTARSRNATLHVA-VLREEFRLEPESKQSAQGDTVVLEC 129 + +G + ATN G A S L A F +S QG V L+ Sbjct: 66 MIPAVTAAHSGRFSVRATNGAGQATSTAELLVTAETAPPNFIQRLQSLTVRQGSQVRLD- 124 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAG 187 + G P P V + + G + D ++ + DG +L+I +A D+G Y A N++G Sbjct: 125 VRVTGIPAPVVKFYREGAEIQSSADFQI-VQDGDLYSLLIAEAFPEDSGTYSVSASNSSG 183 Query: 188 TRESAIATLKIHIKPYLITGPED--VVAQTGSSVTFQCRV 225 R ++ A L + + + + +++ + S T Q RV Sbjct: 184 -RATSTAELLVQGEEEAVPAKKSKTIISASQISQTRQTRV 222 Score = 44.8 bits (101), Expect = 0.015 Identities = 33/112 (29%), Positives = 51/112 (45%), Gaps = 9/112 (8%) Query: 505 GPPTKPITHNVTDTS---VTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV 561 GPP+ P ++T+ + + ++W K G S I+GY +E+ T NSR Sbjct: 13998 GPPSPPQELHITEAARDHICIAWKAPEKNGGSPIIGYHIELCEAGTEKWMRV--NSRPVK 14055 Query: 562 VIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNS 613 + R + ++P Y F VR NS G S PS +S++V D S Sbjct: 14056 ELKYRAGDE----EGIVPEKEYTFRVRAVNSVGASEPSDISENVFAIDSDCS 14103 Score = 44.8 bits (101), Expect = 0.015 Identities = 24/78 (30%), Positives = 44/78 (56%), Gaps = 6/78 (7%) Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRY 178 GD + ++ +P RG P P V WKK+G +L +R++++ + I+DA + DAG+Y Sbjct: 25044 GDDLKID-VPFRGRPSPEVTWKKDGHSL--KQTTRVNVLTSKTLSKITIKDATREDAGKY 25100 Query: 179 QCIARNAAGTRESAIATL 196 + N G + + I+ + Sbjct: 25101 EITLTNTFGVKSAEISVI 25118 Score = 44.8 bits (101), Expect = 0.015 Identities = 26/90 (28%), Positives = 46/90 (51%), Gaps = 6/90 (6%) Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHL---VDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190 G P P + W K+G+ + + +R + + L+++DA + D+G+Y +N AGTR Sbjct: 25450 GRPIPVISWAKDGKEI--EAKARFEISSTLTSTTLIVRDAIRRDSGQYVLTLQNVAGTRS 25507 Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVT 220 A+ K+ +P +GP D+ T T Sbjct: 25508 LAV-NCKVLDRPGPSSGPLDITGLTAEKCT 25536 Score = 44.8 bits (101), Expect = 0.015 Identities = 44/181 (24%), Positives = 76/181 (41%), Gaps = 30/181 (16%) Query: 422 ICTPEPIIAWYFEGEALIQNHRRNVTN--DGTLV-LKDLDKSDSGTYTCVASSRHGKYVW 478 + P+P I WY +G+ L + +++N + T + +++ + ++GTY + G Sbjct: 26532 VAKPQPTIEWYKDGKELESGAQISISNTTEFTCISVREATRLNTGTYELKIKNSLGSAYA 26591 Query: 479 SGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSILG 537 + +LV PGPP I +T ++T+ W G + + Sbjct: 26592 AVRVLVQDK----------------PGPPAGEIQFKKITADTMTIMWDPPADEGGAMVTH 26635 Query: 538 YQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSG 597 Y VE RET + W +I+ ++ V LI G Y+F VR N HG+ Sbjct: 26636 YIVE--KRET--------SRIMWSIISEKLQDCIVTVPRLIKGNEYIFRVRGVNKHGVGD 26685 Query: 598 P 598 P Sbjct: 26686 P 26686 Score = 44.4 bits (100), Expect = 0.019 Identities = 83/331 (25%), Positives = 133/331 (40%), Gaps = 34/331 (10%) Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556 A D + P P P + T SVTL+W+ K G I GY +E+ T Sbjct: 15471 ADDPLTPPSMPAAPEIADKTKHSVTLAWTPPAKDGGRPIKGYIIEI------QDEGTSEW 15524 Query: 557 SRGWVVIARRVH-QTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLW 615 +R V A +H T + + +L Y F + N G S PSP + V + D + Sbjct: 15525 AR--VNDAENLHPSTVFTIPNLPELKKYRFRIIAVNEIGESEPSPRTSEVRIEDIKTAPK 15582 Query: 616 EGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLF-IYFRPLDNI 674 +S T I AT K+ WE E ++ P+D+ Sbjct: 15583 IFMDISADELLCVRAGTPF---KIPATITGRPAPKVTWEFDGKAKTEKKDRLHILPVDS- 15638 Query: 675 TIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGP 734 +E T + + VS LR ++ + I K K N RV + DVP G Sbjct: 15639 QVESTDTTSVVTVPVS------LRSHSGR--YTITAKNKSGQKHVNVRV--NVLDVP-GA 15687 Query: 735 PINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPA--NKSMVAINTTVHQA 792 P +++ + TT+ L W P+ +G G + +++ A K+ N T + Sbjct: 15688 PKELKVTDVTRTTMRLIWKLPD---NDG---GERIKSYFIEKKAVNGKAWTVANATC-AS 15740 Query: 793 TSLIMTNLTSGVSYSVQIAAETIIGLGPFSQ 823 + +++NL G Y ++ AE +G GPF++ Sbjct: 15741 MAFVVSNLLEGQDYFFRVRAENRLGFGPFTE 15771 Score = 44.4 bits (100), Expect = 0.019 Identities = 35/115 (30%), Positives = 53/115 (46%), Gaps = 12/115 (10%) Query: 496 RAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPR 555 +A ++ + PGPPT +T + T ++V L W G S I GY VE + +E Sbjct: 16082 KARNLFTPPGPPTPKVT-DCTKSTVDLEWIPPLNDGGSMITGYFVE-YKQE--------- 16130 Query: 556 NSRGWVVIA-RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 W + + + T +VV L Y F VR N+ G+ P V+D + V D Sbjct: 16131 GQEEWEKVKDKEIRGTKFVVPGLKELGLYRFRVRAVNAAGVGEPGEVADVIEVKD 16185 Score = 44.0 bits (99), Expect = 0.025 Identities = 35/96 (36%), Positives = 46/96 (47%), Gaps = 13/96 (13%) Query: 504 PGPPTKPITHNVTD-TSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562 PGPP K + H D T V L W+ ++ G S I G+ VE + E + W+V Sbjct: 17079 PGPP-KDLHHVDADKTEVWLQWNWPDRTGGSDITGFLVE-YQEE---------GEKDWIV 17127 Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598 + V V L G TY F V+TEN+ GLS P Sbjct: 17128 F-KTVSIPECHVTGLEEGKTYRFRVKTENAIGLSRP 17162 Score = 44.0 bits (99), Expect = 0.025 Identities = 85/347 (24%), Positives = 127/347 (36%), Gaps = 43/347 (12%) Query: 269 EYSCEAENSVGAVSA----SGYLTVYDP---PSINLSPNS---VNVESGNVARFTCTATG 318 E+ A NS GAVS S + D P I+ + V V++G++ + TG Sbjct: 21064 EFRVLARNSAGAVSKPSKPSEVIVCRDDIEEPKIDADASFSSVVVVKAGDIFKLDAHVTG 21123 Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378 RP P++ W+ +G M D + L D+ + D +A N Sbjct: 21124 RPIPSIVWTKDGKELEDTAKME------IKTLDFYSCLINKDSLRRDG-GAYTLTASNPG 21176 Query: 379 GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438 G + + V DRP GP L + M V C P P+ + E Sbjct: 21177 GFAKFVFNVKVL---DRP------GPPEGPLHVTDMTVEKCVLSWLP-PLHDGGGKIEYY 21226 Query: 439 IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAA 498 I R T V DL + Y + +Y++ + + + A Sbjct: 21227 IIQRRETSRLTWTNVATDLQVN---RYKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPAV 21283 Query: 499 DVSS-LPG-PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556 + +P PP P +T S+ + W G SSI Y +E R +G Sbjct: 21284 ATNPYVPSDPPQAPEVTAITKDSMVVCWGHPEYNGGSSINTYIIE---RRDKTGLR---- 21336 Query: 557 SRGWVVIARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602 WV +R V + V L PG Y + + EN+ GLS PSP S Sbjct: 21337 ---WVKCNKRTVTDLRFKVSGLTPGHEYEYRILAENAAGLSAPSPSS 21380 Score = 43.6 bits (98), Expect = 0.034 Identities = 30/91 (32%), Positives = 45/91 (49%), Gaps = 4/91 (4%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM-HLVDGG--NLV 166 F +P ++ +G +VV C GSP+P++YWKK+G L R+ H D G L Sbjct: 877 FVKKPVVQKLVEGGSVVFVC-QIGGSPKPHIYWKKSGVPLTTGYRYRVSHNKDTGECKLE 935 Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATLK 197 I DAG Y A+N G ++ + L+ Sbjct: 936 ISMTFADDAGEYTIFAKNQHGETSASTSLLE 966 Score = 43.6 bits (98), Expect = 0.034 Identities = 34/114 (29%), Positives = 43/114 (37%), Gaps = 11/114 (9%) Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556 A D PGPP V+ T V L W G +L Y +E +E L Sbjct: 13892 AKDTFGTPGPPYNLTITEVSKTHVDLKWEAPQNDGGRPVLRYVIE--KKEKLGTR----- 13944 Query: 557 SRGWVVIARRV-HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 WV + HY V +I G F V EN G+ PS +D V + D Sbjct: 13945 ---WVKSGKTSGPDCHYRVTDVIEGTEVQFQVSAENEAGVGHPSEPTDIVVIED 13995 Score = 43.6 bits (98), Expect = 0.034 Identities = 37/104 (35%), Positives = 50/104 (48%), Gaps = 12/104 (11%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 P P KP +VT +S+ ++W + N GS+ I GY VE RE NS W + Sbjct: 14673 PDAPEKPEIKDVTASSMCVTWLEPNDNGSA-IEGYWVE--KREI--------NSTHWARV 14721 Query: 564 ARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVT 606 R V V+ L+ G+TY+F V EN G SP S+ T Sbjct: 14722 NRTMVPDLEINVEGLLEGLTYIFRVCAENIAGPGKFSPPSEPKT 14765 Score = 43.6 bits (98), Expect = 0.034 Identities = 35/114 (30%), Positives = 46/114 (40%), Gaps = 9/114 (7%) Query: 496 RAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPR 555 +A DV +P P P+ + + +SW Q G I Y VE +ET N R Sbjct: 16673 KAKDVFKVPDAPQAPVVKEIYKDTALISWLQPAD-GGKPITNYIVE--KKET-KANMWAR 16728 Query: 556 NSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 + R T Y V L+ G Y F V EN G+ PSP S + D Sbjct: 16729 AGKD-----RIFPNTEYWVPDLLKGCEYEFRVMAENVIGIGDPSPSSKPIYAKD 16777 Score = 43.6 bits (98), Expect = 0.034 Identities = 33/105 (31%), Positives = 45/105 (42%), Gaps = 14/105 (13%) Query: 506 PPTKPIT---HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562 PP++P+ + V+ V LSW + G S++ GY +E RNS WV Sbjct: 18760 PPSEPLNCCVNKVSKEFVVLSWEKPVNDGGSALTGYFIE----------RKERNSLLWVR 18809 Query: 563 IAR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVT 606 V T Y LI G+ Y F V N G PS +D +T Sbjct: 18810 TNEVLVRSTEYTCSGLIEGLEYTFRVSAVNKAGQGKPSKQTDFIT 18854 Score = 43.6 bits (98), Expect = 0.034 Identities = 36/108 (33%), Positives = 50/108 (46%), Gaps = 11/108 (10%) Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556 AA +PG P P T ++T+SW++ + G S ILGY +E +N Sbjct: 20888 AAYPFDVPGQPGIPQIVAFTKDAMTISWNEPSSDGGSPILGYHIE----------RKEKN 20937 Query: 557 SRGWVVIARRVHQTHYVVKS-LIPGITYMFIVRTENSHGLSGPSPVSD 603 S W I++ V + S L+ GI Y F V EN GLS S S+ Sbjct: 20938 SILWQRISKAVVVGNMFKSSGLMDGIAYEFRVIAENLAGLSKASKPSE 20985 Score = 43.6 bits (98), Expect = 0.034 Identities = 83/327 (25%), Positives = 123/327 (37%), Gaps = 47/327 (14%) Query: 291 DPPSINLSPN---SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347 D P I L + V +G R GRP P + W+ + G DK Sbjct: 23655 DAPEIELDSELRKGIVVHAGGSMRINIPFKGRPIPEINWTKDD-------GDLPDKAQID 23707 Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG--SSFVRGKLTVTSDDDRPPPIITNGPS 405 D T LTIN D+ND+ + N AG S+FV K+ D P P Sbjct: 23708 KGPD-FTHLTINICDRNDA-GKYTLTLQNSAGTKSAFVSVKVL-----DTP-----GAPQ 23755 Query: 406 NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH---RRNVTNDGTLVLKDLDKSDS 462 N L +K + T + P P+I +G + I+N+ +R T G + K Sbjct: 23756 N--LFVKDITRNYVTLVWEP-PLI----DGGSKIKNYIIDKRESTRQGFTNITT--KCSK 23806 Query: 463 GTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTL 522 ++ + G Y + + I + + + P K +VT T+ +L Sbjct: 23807 TSFRVGDLTEGGIYYFRVMAENEFGIGLPVETEESVKTADPPLSVGKVTLTDVTKTTASL 23866 Query: 523 SWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGIT 582 SW + + G S ILGY +E+ P+ S W+V A V L G Sbjct: 23867 SWDKPDHDGGSRILGYYIEM----------QPKGSEEWIV-ATVCKTCEGTVAGLSSGQE 23915 Query: 583 YMFIVRTENSHGLSGPSPVSDSVTVGD 609 Y+ V N G S P P++ V D Sbjct: 23916 YLLRVLAYNEKGKSDPRPLASPVIAKD 23942 Score = 43.2 bits (97), Expect = 0.044 Identities = 34/142 (23%), Positives = 62/142 (43%), Gaps = 6/142 (4%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-THRSILPAGGLFFLR 70 P +++P + Q A + + G P P W+ G VV+D TH+ ++ G + Sbjct: 1229 PVFVQKPSSFRCSEGQTARFDLKVVGRPMPDTFWFHSGQQVVNDYTHKIVVKEDGTQSMI 1288 Query: 71 ATHGRVHSDAGVYWCEATNSYG-TARSRNATLHVA--VLREEFRLEPESKQSAQGDTVVL 127 + D+G + A N G T S T+ ++R +F +E S + ++V Sbjct: 1289 VVPA-MPQDSGEWTVVAQNRAGKTTVSMTLTVEAKENLVRPQF-IEKLKNISVKEGSLVE 1346 Query: 128 ECLPPRGSPEPNVYWKKNGQTL 149 + G+P P++ W KN + Sbjct: 1347 LAVKAIGNPLPDIVWLKNSDII 1368 Score = 43.2 bits (97), Expect = 0.044 Identities = 39/135 (28%), Positives = 62/135 (45%), Gaps = 8/135 (5%) Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSN-SRVAQTLDDV-PDGPPINIEMFILNTTTVH 749 F+++ L + +YEF + K G+PS S+ T D P GPP N + TT Sbjct: 20267 FKVSGLSEEIEYEFRVTAENKAGFGEPSEPSQPVMTKDIAYPPGPPSNPRITDTTKTTAT 20326 Query: 750 LKWSPPELQLQNGI-ITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSV 808 W P G+ +TGY +V + + + V T + T +++NL SG Y Sbjct: 20327 FNWGRPFYD--GGLDVTGY-IVEHKKE--GDDDWVQDTTIPLRITEFVVSNLQSGGKYHF 20381 Query: 809 QIAAETIIGLGPFSQ 823 +++A GLG S+ Sbjct: 20382 RVSALNSEGLGEPSE 20396 Score = 43.2 bits (97), Expect = 0.044 Identities = 37/128 (28%), Positives = 53/128 (41%), Gaps = 13/128 (10%) Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543 V P P + +F+AAD PGPP P V+ SV L WS+ G I Y VE Sbjct: 22455 VGKPSPPTV-YFKAADPVFKPGPPNNPKVAYVSRASVVLHWSKPIYDGGCEIQSYIVE-- 22511 Query: 544 SRETLSGNNTPRNSRGWVVIA--RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPV 601 + E S WV+ + +T + K L+ Y F + N G+ + + Sbjct: 22512 ACEVTSDE--------WVMCTPPSGITETRFEAKKLLEKHEYKFRICAVNKIGVGETADI 22563 Query: 602 SDSVTVGD 609 SV + D Sbjct: 22564 PGSVIIED 22571 Score = 43.2 bits (97), Expect = 0.044 Identities = 32/107 (29%), Positives = 42/107 (39%), Gaps = 11/107 (10%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 PGPP P S+ + W + G S+ILGY +E +NS W I Sbjct: 23058 PGPPGTPFVSAFNKESMVVEWHKPVSDGGSAILGYHLE----------RKEKNSILWTKI 23107 Query: 564 AR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 + + T Y L GI Y F V EN G+ S S+ D Sbjct: 23108 NKILIQDTRYKTSPLEEGIEYEFRVYAENIVGIGKCSKTSEGCIARD 23154 Score = 43.2 bits (97), Expect = 0.044 Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 9/106 (8%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 PGPPT + T + + ++W++ G S I+GY +E + ++ + +RG + Sbjct: 25222 PGPPTSLQVSHATKSGMLVTWNRPASDGGSPIVGYHIECKDQSSILWT---KMNRGLIT- 25277 Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 +T + V L G+ Y + V EN G+ + D V+ D Sbjct: 25278 -----ETQFKVTGLEEGLQYQYRVYAENIAGIGPCTKACDPVSARD 25318 Score = 43.2 bits (97), Expect = 0.044 Identities = 36/120 (30%), Positives = 54/120 (45%), Gaps = 9/120 (7%) Query: 87 ATNSYGTARSRNATLHVAV-LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145 +++S+ S A LH A L PE G + + C G P P++ W + Sbjct: 32640 SSHSHAEETSVRAALHSAQGLAPRIEALPEDISVETGKVLTVACAFS-GEPAPHIEWSRG 32698 Query: 146 GQTLLFDGD-SRMHL---VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201 G+ L + D SR H+ D L+I ++TDAG Y N G S +AT+ I I+ Sbjct: 32699 GKKLPGEEDSSRFHIETTEDLTTLIITGVKETDAGAYTLKLSNEHG---SDLATVTISIR 32755 Score = 42.7 bits (96), Expect = 0.059 Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 4/111 (3%) Query: 1 MSDDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI 60 ++ D ++ P I+ P + V + A CR G P+P + WY G L++ + R Sbjct: 1602 VTGDDMSEKSKPEIVLLPEPIRVFEGETAKYRCRVTGYPTPKVNWYLNG-LLIRKSKRFR 1660 Query: 61 LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR 111 L G+ +L T + + D+G A N GTA L + +E+FR Sbjct: 1661 LHYDGIHYLEITDCKSY-DSGDVRVLAENPEGTA-EHTVKLEIQ-QKEDFR 1708 Score = 42.7 bits (96), Expect = 0.059 Identities = 30/102 (29%), Positives = 45/102 (44%), Gaps = 8/102 (7%) Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352 P I L P + V G A++ C TG P P + W + G ++ R + H +DG Sbjct: 1613 PEIVLLPEPIRVFEGETAKYRCRVTGYPTPKVNWYLNG---LLIRKSKRFRLH----YDG 1665 Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394 + L I D DS + V A N G++ KL + +D Sbjct: 1666 IHYLEITDCKSYDSGDVRVL-AENPEGTAEHTVKLEIQQKED 1706 Score = 42.7 bits (96), Expect = 0.059 Identities = 33/121 (27%), Positives = 51/121 (42%), Gaps = 12/121 (9%) Query: 481 ALLVDSPINPNIHFFRAADVSSL--PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGY 538 A + +N + DV+ L PGPP +T+ S L+W+ G S + Y Sbjct: 13474 ATYIIEAVNSSGRATATVDVNILDKPGPPAAFDISEITNESCVLAWNPPRDDGGSKVTNY 13533 Query: 539 QVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598 VE R+ + +S W ++ V QT Y L+ Y+F V EN G+ P Sbjct: 13534 IVE---RKAV-------DSEIWYKLSSTVKQTTYKATKLVAFKEYIFRVYAENQFGIGAP 13583 Query: 599 S 599 + Sbjct: 13584 A 13584 Score = 42.7 bits (96), Expect = 0.059 Identities = 32/107 (29%), Positives = 44/107 (41%), Gaps = 12/107 (11%) Query: 506 PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565 PP KP NVT SVTL W+ G + GY VE + W+ Sbjct: 19912 PPGKPDVINVTRNSVTLMWTAPKYDGGHKLTGYMVEKLEHP----------GKTWMKANH 19961 Query: 566 -RVHQTHYVVKSLIPGITYMFIVRTENSHG-LSGPSPVSDSVTVGDD 610 V Y V L G T F +R +N+ G +S PS ++ + D+ Sbjct: 19962 VNVQSCAYTVTDLQEGCTCEFRIRAKNAAGAISAPSETTEPLVCKDE 20008 Score = 42.3 bits (95), Expect = 0.078 Identities = 51/213 (23%), Positives = 73/213 (34%), Gaps = 20/213 (9%) Query: 20 DVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS 78 D T + A C P + WYKG + S I G L+ + Sbjct: 7816 DQTTTVKKEAVFECEIKINYPEITLSWYKGTQKLDSGDKYDIKIVGDRHILKIKDCQTR- 7874 Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138 D G Y +A+ + VL E + +G T L C P Sbjct: 7875 DEGNYRIVCGPHISSAK-------LTVLEAEVEKPMQDVAGKEGQTCTLTC--QLSVPNV 7925 Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGG---NLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195 W +NG+ L + SR L I+D R D G Y C +N T I Sbjct: 7926 KTQWFRNGK--LLEPHSRYTCAVANYTQKLSIKDVRPEDQGEYTCKYKNLETTANLWIEA 7983 Query: 196 LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228 +IH + +++V + S TF+C V D Sbjct: 7984 EQIHFTKRI----QNIVVREHQSATFECEVSFD 8012 Score = 42.3 bits (95), Expect = 0.078 Identities = 41/163 (25%), Positives = 72/163 (44%), Gaps = 15/163 (9%) Query: 122 GDTVVLECLPPRGSPEPNVY-WKKNGQTLLFDGDSRMHLVDGGNLVIQ--DARQTDAGRY 178 G + V EC + SP + W K+G L + DG + +Q D + +D G Y Sbjct: 10835 GSSAVFEC---QISPSTAITTWMKDGSNLR-ESPKHKFTSDGKDRKLQIIDVQLSDTGEY 10890 Query: 179 QCIAR--NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 C+A+ N T + + ++ +K + T E++ G + C + D DV+W+ Sbjct: 10891 TCVAKLGNKEKTSTAKLIVEELPVK-FTKTLEEEMSVIKGQPMYLTCELSKD--RDVVWK 10947 Query: 237 RSAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAEN 276 ++ G+V+V G S + + D G Y+CE E+ Sbjct: 10948 KNGKELKQIAGKVQVNVIGLQRSATIQDTNDDDAGVYTCECED 10990 Score = 42.3 bits (95), Expect = 0.078 Identities = 49/186 (26%), Positives = 68/186 (36%), Gaps = 29/186 (15%) Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481 P P W F AL R ++ T LV+ ++D GTY+ + Sbjct: 13137 PIPTAKWTFGENALTAGDRVSMVTKSTFTELVITPSVRADKGTYSLTLEN--------DV 13188 Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541 V I N+ ++S P P VT V L W G S I GYQVE Sbjct: 13189 ASVSGEIEVNV-------IAS-PSAPKDLKVAEVTRKHVHLMWEAPEHDGGSPITGYQVE 13240 Query: 542 VFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPV 601 RE + + WV + + Y V ++ G Y+F V N G P+ + Sbjct: 13241 --KREV--------SRKTWVKVMSGLQDQEYTVTDVVEGKEYLFRVIACNKCGPGEPAYI 13290 Query: 602 SDSVTV 607 D V V Sbjct: 13291 EDPVNV 13296 Score = 42.3 bits (95), Expect = 0.078 Identities = 43/156 (27%), Positives = 67/156 (42%), Gaps = 11/156 (7%) Query: 165 LVIQDARQTDAGRYQCIARNAAG---TRES-AIATLKIHIKPYLITGPEDVVAQTGSSVT 220 +V+ ++ R++ ARNA G RE+ I +K + I + V A+ GS + Sbjct: 18528 IVVAGLKENTKYRFRVAARNAIGCSLAREAEGIFEVKEQLMAPKIIVSDVVTARAGSKLI 18587 Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMPLGRV---KVLDDGSLRLDNVILADEGEYSCEAENS 277 V G P P W+R + + RV K L + +V D G YS AENS Sbjct: 18588 VDALVSGKPAPVTKWKRGS-DDIVTSDRVVIQKTPTTSLLMVKDVTRKDSGYYSLSAENS 18646 Query: 278 VGAVSASGYLTVYD---PPSINLSPNSVNVESGNVA 310 V+ + + D PP L V+V++ +A Sbjct: 18647 TAKVNQIIRIIIMDIPGPPQGPLQILEVDVDACTLA 18682 Score = 42.3 bits (95), Expect = 0.078 Identities = 47/182 (25%), Positives = 66/182 (36%), Gaps = 27/182 (14%) Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHGKYVWSGALL 483 P P + WY E L + T TLV + + + D+G Y + GK +G + Sbjct: 20440 PAPEVVWYKENVPLKGRAHIDTTESYTLVVIPECTRYDAGKYVLTLENVAGKK--TGFVN 20497 Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543 V R D PGPP +T S+TL W G S I Y +E Sbjct: 20498 V-----------RVVDT---PGPPVNLKPREITKHSITLQWEIPLIDGGSKIKNYIIE-- 20541 Query: 544 SRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603 RE + + VI + Y + L Y F V EN G+ P+ D Sbjct: 20542 KREA--------TRKAYSVITTNWQKCSYKIPDLEEAAEYYFRVSAENEMGIGEPAETPD 20593 Query: 604 SV 605 + Sbjct: 20594 PI 20595 Score = 42.3 bits (95), Expect = 0.078 Identities = 31/106 (29%), Positives = 52/106 (49%), Gaps = 7/106 (6%) Query: 106 LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN- 164 + F+L + G+ + +E +P +G P P + W K+GQ L +R+++ Sbjct: 23945 IEPSFKLTFNTYSVQSGEDLKVE-IPFKGRPTPKIGWMKDGQAL--KETTRLNVSSTATS 24001 Query: 165 --LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208 L I++A + D+G+Y A N GT +A + I KP TGP Sbjct: 24002 TVLKIKEANREDSGKYTITATNNIGTVTEEVAII-ILDKPGPPTGP 24046 Score = 42.3 bits (95), Expect = 0.078 Identities = 37/162 (22%), Positives = 60/162 (37%), Gaps = 14/162 (8%) Query: 444 RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSL 503 +N++ D +++ + S + V GKY+ L +++ + + V Sbjct: 26945 KNISGDARYAIRNTEYSTTLIIPKVTRDDTGKYL----LEIENGVGEPKTITVSVKVLDT 27000 Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 P + I NVT +TLSW G S I Y VE + + ++ Sbjct: 27001 PSACNRLIVKNVTRGKLTLSWEPPYIDGGSPITNYVVE----------KKDAKMKAFTIV 27050 Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605 T Y V L I+Y F V EN +G+ P V Sbjct: 27051 TNECANTTYKVDGLSEEISYFFRVSAENEYGVGDPCETEQPV 27092 Score = 42.3 bits (95), Expect = 0.078 Identities = 39/142 (27%), Positives = 66/142 (46%), Gaps = 20/142 (14%) Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP---GMSRDKYHATAVFDGV-- 353 P+S+ V G+ ARF C G P PT+ W EG RT++ +S +Y +T V Sbjct: 32143 PHSLIVSEGDSARFVCDIDGEPAPTVTWMHEG-RTVVSSHRIHVSTTQYKSTLEISSVEY 32201 Query: 354 ------TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407 TV+ N K ++R T+ A+N ++ ++T T P + + P + Sbjct: 32202 SDEGNYTVVVENSEGKQEARCTL---AIN---KPILKEEVTPTQVKSPEPSVASPVPPIK 32255 Query: 408 TLPIKSMAVFPCTAICTPEPII 429 + P +S P ++ +PEP + Sbjct: 32256 S-P-ESSVTSPVPSVKSPEPSV 32275 Score = 41.9 bits (94), Expect = 0.10 Identities = 52/195 (26%), Positives = 68/195 (34%), Gaps = 27/195 (13%) Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCE 273 G SV F V G P P V W + + V+ D+ SL + V EGEYSC Sbjct: 3418 GESVRFTVTVSGFPKPKVQWFHNGKAITSSSIYTFVEERDEYSLIITKVKKDYEGEYSCT 3477 Query: 274 AENSVGAVSASGYLTVY-------------------DPPSINLSPNSVNVESGNVARFTC 314 A N G + L V PP V G+ +F Sbjct: 3478 ASNRFGQTTCKTILKVELSQLSAAEKWVEKMFKIPGQPPCFTTQIQPVQCVEGSEVKFQY 3537 Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374 TG P P + W +GN I S DG L +++ + DS C A Sbjct: 3538 KVTGTPFPDVQW-FKGNSQI----KSSQTCSVVCNPDGSGFLIMSNIQQRDS-GLYTCKA 3591 Query: 375 VNYAGSSFVRGKLTV 389 VN G + +L V Sbjct: 3592 VNPFGEASCSAELIV 3606 Score = 41.9 bits (94), Expect = 0.10 Identities = 66/324 (20%), Positives = 120/324 (37%), Gaps = 38/324 (11%) Query: 499 DVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558 ++ PGPP + S+ W G S IL Y +E + + Sbjct: 14567 NILDTPGPPVNFKFEEIRKNSILCKWDPPLDDGGSEILNYILE--------RKDNSKAEL 14618 Query: 559 GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGT 618 GW+ + + ++V LI G Y+F V EN +G P +T + + ++ Sbjct: 14619 GWITVTSILRGCKFLVPKLIEGKEYLFRVTAENKYG-----PGKPCITKPVIARNPFDPP 14673 Query: 619 GVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEY 678 E ++ + V +E P D N +EG ++ R +++ Sbjct: 14674 DAPEKPEIKDVTASSMCVTWLE--PND-----------NGSAIEGYWVEKREINSTHWAR 14720 Query: 679 EMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGK---PSNSRVAQTLDDVPDGPP 735 +T++ +++ + L + Y F + GK PS + AQ +P GPP Sbjct: 14721 VNRTMVPDLEIN---VEGLLEGLTYIFRVCAENIAGPGKFSPPSEPKTAQA-PIMPPGPP 14776 Query: 736 INIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSL 795 I + + ++ ++W PP NG + V+ L V K H+ + Sbjct: 14777 IP-RIVDTSDYSIDIEWDPP---ADNGGAEVFGYHVDKL-VAGTKDWSRATERPHKTRTF 14831 Query: 796 IMTNLTSGVSYSVQIAAETIIGLG 819 + + G Y V++ A G G Sbjct: 14832 TVYGVREGAKYIVRVVAINCAGEG 14855 Score = 41.5 bits (93), Expect = 0.14 Identities = 28/104 (26%), Positives = 43/104 (41%), Gaps = 10/104 (9%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 PGPP VT +S T++W + G + + Y V++ RE GW I Sbjct: 25913 PGPPAHIEVKEVTKSSATITWDTPDNEGGAPVKNYLVDL--REA--------TKMGWSRI 25962 Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607 + + Y V +L G Y F V EN +G+ P + + Sbjct: 25963 SNSCPRLTYKVTNLQEGGVYYFRVTGENEYGVGVPLETKEGTKI 26006 Score = 41.5 bits (93), Expect = 0.14 Identities = 79/366 (21%), Positives = 131/366 (35%), Gaps = 40/366 (10%) Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVY---DPPSINLSPNSVNVESGNVARFTC 314 R+ N+ +E E+ AEN G ASG ++ +P S +P V V T Sbjct: 27845 RVTNLTEGNEYEFRVMAENGAGIGPASGISRLFKCREPTSAPSAPTLVKVIDSTKTSVTL 27904 Query: 315 TATGRPEPTMFWSVEGNRTII-FPGMSRDKYHATAVFDGV-TVLTINDTDKNDSRNTIVC 372 T +P +E II S +++H + T + + + + VC Sbjct: 27905 AWT---KPVFDGGLEIIGYIIEMCKASLEEWHRVNNQTCIQTHYRVTELESGEEYKFRVC 27961 Query: 373 SAVNYAGSSFVRGKLTVTSDDDR--PPPIITNGPSNQTLPIKSMAVFPCTAICT--PEPI 428 AVN AG + DR P I + QT +K+ P P+ Sbjct: 27962 -AVNGAGKGEFSETPHIVQAVDRLTSPEIDIDADFKQTHIVKNGGTVKLHIPFRGKPVPL 28020 Query: 429 IAWY-FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 W +G+ + TL +++ + D+G YT + G+ + Sbjct: 28021 ATWTKADGDLGVMVDINTTDTFSTLTIENCTRYDAGKYTLSLENNSGRKTIT-------- 28072 Query: 488 INPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRET 547 V PGPP +VT ++TL W + G + + Y VE Sbjct: 28073 --------LTVKVLDTPGPPGPLSFKDVTRGALTLMWDAPSNDGGARVHHYIVEKREASR 28124 Query: 548 LSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607 LS W ++ R + V +L G+ Y F V EN +G P +++ + Sbjct: 28125 LS----------WQEVSERCTRQILRVINLDIGVAYFFRVTAENQYGKGEPYEMTEPIIA 28174 Query: 608 GDDSNS 613 ++ S Sbjct: 28175 TEEPAS 28180 Score = 41.1 bits (92), Expect = 0.18 Identities = 33/110 (30%), Positives = 49/110 (44%), Gaps = 11/110 (10%) Query: 500 VSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRG 559 +S +P PP K +VT SV+L W + G S I Y+VE+ +++ Sbjct: 22762 ISEVPQPPGKVSVVDVTRKSVSLKWEKPEHDGGSRITYYEVEMQAKD----------QDK 22811 Query: 560 WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 W + A +V VV +L G Y+F V N G S P ++ V D Sbjct: 22812 WSLCA-QVKALDTVVTNLAQGGEYIFRVIAVNDKGKSDPRLLASPVVAKD 22860 Score = 41.1 bits (92), Expect = 0.18 Identities = 17/39 (43%), Positives = 27/39 (69%) Query: 785 INTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQ 823 +NTTV +AT +TN+ +G+ Y ++AAE G+GP S+ Sbjct: 26354 VNTTVIRATHFKVTNVNAGLIYEFKVAAENAAGIGPISK 26392 Score = 40.7 bits (91), Expect = 0.24 Identities = 29/90 (32%), Positives = 45/90 (50%), Gaps = 7/90 (7%) Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRY 178 GD + +E +P G P P V WKK Q L R+++ + + L I + ++ D G+Y Sbjct: 20716 GDNLKVE-IPVLGRPRPLVVWKKEDQEL--KQTQRINIENTASSTILNINEIKRKDGGQY 20772 Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGP 208 +N GT I T+++H P TGP Sbjct: 20773 SMTGKNILGTVTENI-TVQVHDIPGPPTGP 20801 Score = 40.7 bits (91), Expect = 0.24 Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 1/59 (1%) Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEV 542 V P P + +++A D + PG PT + T SVT++WS+ G I GY VE+ Sbjct: 23536 VGQPSQPTV-YYKACDPTFKPGQPTNAHLVDTTKNSVTVAWSRPIYDGGLDIQGYVVEI 23593 Score = 40.7 bits (91), Expect = 0.24 Identities = 52/202 (25%), Positives = 79/202 (39%), Gaps = 15/202 (7%) Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 PP L + + G RF T T PEP++ W G+R I P KY T+ Sbjct: 31321 PPEFTLPLFNRSAYIGEDVRFGVTITVHPEPSVTWLKAGHR--IKP--DPKKYTFTS-DK 31375 Query: 352 GVTVLTINDTD-KNDSRNTIVCSAVNYAGSSFVRGKLTVTSD---DDRPPPIITNGPSNQ 407 G+ L I++ D +D+ T+V A N G + +L V +D P+ +N Sbjct: 31376 GLYQLMIHNVDLSDDAEYTVV--ANNKFGEDSCKARLNVAPHAVAEDTMRPMFKRLLANI 31433 Query: 408 TLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT----LVLKDLDKSDSG 463 F TP P + W G+ L + V + L +++ DSG Sbjct: 31434 DCVEGQSVRFDLRVSGTPAPTLKWEKNGKPLEFRPQVEVVQEDVDYFILHIRETLIEDSG 31493 Query: 464 TYTCVASSRHGKYVWSGALLVD 485 TY A++ G L V+ Sbjct: 31494 TYRVTATNTAGSASCQATLKVE 31515 Score = 40.7 bits (91), Expect = 0.24 Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 4/92 (4%) Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86 Q + R G+P+P ++W K G + ++ +F+ + D+G Y Sbjct: 31439 QSVRFDLRVSGTPAPTLKWEKNGKPLEFRPQVEVVQEDVDYFILHIRETLIEDSGTYRVT 31498 Query: 87 ATNSYGTARSRNATLHVAVL---REEFRLEPE 115 ATN+ G+A S ATL V L R EF+ E E Sbjct: 31499 ATNTAGSA-SCQATLKVERLTYTRREFKSEEE 31529 Score = 40.3 bits (90), Expect = 0.31 Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 1/87 (1%) Query: 107 REEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV 166 + E L PE + +G+T C G P P V W NG + R+H L Sbjct: 1612 KPEIVLLPEPIRVFEGETAKYRCRVT-GYPTPKVNWYLNGLLIRKSKRFRLHYDGIHYLE 1670 Query: 167 IQDARQTDAGRYQCIARNAAGTRESAI 193 I D + D+G + +A N GT E + Sbjct: 1671 ITDCKSYDSGDVRVLAENPEGTAEHTV 1697 Score = 40.3 bits (90), Expect = 0.31 Identities = 51/204 (25%), Positives = 84/204 (41%), Gaps = 23/204 (11%) Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR---TIIFPGMS-RDKYHA--TAV- 349 L+P V + G RFT T +G P+P + W G + I+ + RD+Y T V Sbjct: 3410 LTPAEVTI--GESVRFTVTVSGFPKPKVQWFHNGKAITSSSIYTFVEERDEYSLIITKVK 3467 Query: 350 --FDGVTVLTINDTDKNDSRNTIVCSAVNY--AGSSFVRGKLTVTSDDDRPPPIITNGPS 405 ++G T ++ + TI+ ++ A +V + PP T Sbjct: 3468 KDYEGEYSCTASNRFGQTTCKTILKVELSQLSAAEKWVEKMFKIPGQ----PPCFTTQIQ 3523 Query: 406 NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR-----NVTNDGTLVLKDLDKS 460 S F TP P + W F+G + I++ + N G L++ ++ + Sbjct: 3524 PVQCVEGSEVKFQYKVTGTPFPDVQW-FKGNSQIKSSQTCSVVCNPDGSGFLIMSNIQQR 3582 Query: 461 DSGTYTCVASSRHGKYVWSGALLV 484 DSG YTC A + G+ S L+V Sbjct: 3583 DSGLYTCKAVNPFGEASCSAELIV 3606 Score = 40.3 bits (90), Expect = 0.31 Identities = 31/106 (29%), Positives = 43/106 (40%), Gaps = 10/106 (9%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 P PP + + + S L W+ + G S I Y VE R+ +GW + Sbjct: 13799 PSPPRWLLVVSSSRNSAELKWTAPERDGGSPITNYIVE--KRDV--------RRKGWQAV 13848 Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 V + Y V L G Y+F V EN+ G S + DSV D Sbjct: 13849 DTTVKELKYTVTPLNEGSLYVFRVAAENAVGPSEFCELEDSVLAKD 13894 Score = 40.3 bits (90), Expect = 0.31 Identities = 96/480 (20%), Positives = 169/480 (35%), Gaps = 46/480 (9%) Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193 G P P + W ++ L + + LVI+ + G Y A+NA G R+ A+ Sbjct: 16218 GKPAPEIIWNRDDAELPKEAAVETTSISSA-LVIKSCLRQHQGIYTLTAKNAGGERKKAV 16276 Query: 194 ATLKIHIK-PYLITGPEDVVAQTGSSVTFQCRV--GGDPLPD-VLWRRSAGGGNMPLGRV 249 + + P + + + +T+ GG + + ++ +R A Sbjct: 16277 IVEVLDVPGPVGLPFSGENLTNDSCKLTWYSPEDDGGSAITNYIIEKREADRRGWTSVTY 16336 Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGA---VSASGYLTVYDPPSINLSPNSVNVES 306 V ++ + +I + AEN +G + + + DP S+ P V V + Sbjct: 16337 TVTRHNAV-VQGLIDGKGYFFRIAAENIIGMGPFTETAAPVVIKDPLSVPERPEDVEVTA 16395 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD-KND 365 + + + R S + + + +D + A D + K Sbjct: 16396 --ITNDSISVAWRSPKYDGGSDITSYVLEVRLIGQDNFSRIAKEDKLMDRKFTHAGLKEG 16453 Query: 366 SRNTIVCSAVNYAGS---SFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422 S SAVN G SF +T + + PP + + + + Sbjct: 16454 SSYEFRVSAVNQIGQGKPSFSTKPVTCKKEFE-PPNLDLEFRDKLVVRVGETCIIQSRYT 16512 Query: 423 CTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479 PEP I W+ E L N +T N +L ++ + SG Y V + G Sbjct: 16513 GKPEPTIKWFKNDEELQANEEIALTTAKNRLSLTIEKAKRDHSGKYMVVLENSIGTR--K 16570 Query: 480 GALLVDSPINPNIHFFRAADVSSLPGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSILGY 538 G V+ V P PP P+ + + + +SW+ G ++I Y Sbjct: 16571 GICTVN--------------VVDRPQPPEGPVIFDEIYRNYMVISWNPPLDDGGAAISNY 16616 Query: 539 QVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598 VE R+T N W+ + +T V LI G Y+ + +N HG+S P Sbjct: 16617 IVE--KRDT--------NRDLWMPVTESCTRTSCKVPKLIEGREYIIRICAQNIHGISDP 16666 Score = 40.3 bits (90), Expect = 0.31 Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 1/84 (1%) Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGE 269 +V + G SV + + G P P V W + G+ P + D S L +D G+ Sbjct: 17879 IVVKAGESVRLEAGLRGKPQPTVTWVKDKATGDNPRISIDTGHDYSKFLLTKTKRSDTGK 17938 Query: 270 YSCEAENSVGAVSASGYLTVYDPP 293 Y A N G+ +A +TV D P Sbjct: 17939 YVVTATNPAGSFTAYANVTVLDIP 17962 Score = 40.3 bits (90), Expect = 0.31 Identities = 34/124 (27%), Positives = 49/124 (39%), Gaps = 10/124 (8%) Query: 495 FRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTP 554 F + V PG P ++T VTL W G S I Y ++ RE+ Sbjct: 23742 FVSVKVLDTPGAPQNLFVKDITRNYVTLVWEPPLIDGGSKIKNYIID--KRES------- 23792 Query: 555 RNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSL 614 +G+ I + +T + V L G Y F V EN G+ P +SV D S+ Sbjct: 23793 -TRQGFTNITTKCSKTSFRVGDLTEGGIYYFRVMAENEFGIGLPVETEESVKTADPPLSV 23851 Query: 615 WEGT 618 + T Sbjct: 23852 GKVT 23855 Score = 40.3 bits (90), Expect = 0.31 Identities = 30/101 (29%), Positives = 50/101 (49%), Gaps = 8/101 (7%) Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILADE 267 V + +++ + G P P+V W+++ G +P R ++ GS L +DNV D Sbjct: 24752 VTVRASATLRLFVTIRGRPEPEVKWKKA--DGTLP-ERAQIEVTGSYTGLVIDNVNRFDT 24808 Query: 268 GEYSCEAENSVGAVSASGYLTVYDPPS--INLSPNSVNVES 306 G+Y EN++G+ SA + V D PS +N V +S Sbjct: 24809 GKYVLTLENNIGSKSAFVNVKVLDSPSAPVNFEVKDVKRDS 24849 Score = 40.3 bits (90), Expect = 0.31 Identities = 24/84 (28%), Positives = 42/84 (50%), Gaps = 2/84 (2%) Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG-SLRLDNVILADEGE 269 V + G+++ V G P P + WR++ G G + ++ SL ++ V D G+ Sbjct: 29088 VCIRAGNTLRLNVTVSGRPAPVITWRKT-GIDLQSRGFIDTTENSTSLIVEKVHRYDAGK 29146 Query: 270 YSCEAENSVGAVSASGYLTVYDPP 293 Y+ EAEN G + + + +YD P Sbjct: 29147 YTIEAENPSGKKTITILVKIYDTP 29170 Score = 40.3 bits (90), Expect = 0.31 Identities = 35/128 (27%), Positives = 54/128 (42%), Gaps = 6/128 (4%) Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73 I+ +P + V+ A C G P+P + W G VVS +HR + Sbjct: 32139 ILTKPHSLIVSEGDSARFVCDIDGEPAPTVTWMHEGRTVVS-SHRIHVSTTQYKSTLEIS 32197 Query: 74 GRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP 132 +SD G Y NS G +R ++ +L+EE + P +S + V +PP Sbjct: 32198 SVEYSDEGNYTVVVENSEGKQEARCTLAINKPILKEE--VTPTQVKSPEPS--VASPVPP 32253 Query: 133 RGSPEPNV 140 SPE +V Sbjct: 32254 IKSPESSV 32261 Score = 40.3 bits (90), Expect = 0.31 Identities = 28/88 (31%), Positives = 41/88 (46%), Gaps = 4/88 (4%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRS---ILPAGG 65 G AP I P D++V + T+ C G P+P I W +GG + + S I Sbjct: 32659 GLAPRIEALPEDISVETGKVLTVACAFSGEPAPHIEWSRGGKKLPGEEDSSRFHIETTED 32718 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGT 93 L L T G +DAG Y + +N +G+ Sbjct: 32719 LTTLIIT-GVKETDAGAYTLKLSNEHGS 32745 Score = 39.9 bits (89), Expect = 0.41 Identities = 26/78 (33%), Positives = 39/78 (50%), Gaps = 4/78 (5%) Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTC 467 I S AVF C I I W +G L ++ + T+DG L + D+ SD+G YTC Sbjct: 10834 IGSSAVFECQ-ISPSTAITTWMKDGSNLRESPKHKFTSDGKDRKLQIIDVQLSDTGEYTC 10892 Query: 468 VASSRHGKYVWSGALLVD 485 VA + + + L+V+ Sbjct: 10893 VAKLGNKEKTSTAKLIVE 10910 Score = 39.9 bits (89), Expect = 0.41 Identities = 30/96 (31%), Positives = 41/96 (42%), Gaps = 11/96 (11%) Query: 504 PGPPTKPIT-HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562 PG P PI V + LSW+ G S I Y VE RE N + WV Sbjct: 15990 PGVPVGPIKIGEVFAERIGLSWNPPADDGGSKITNYVVE--KRE--------ENRKTWVH 16039 Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598 ++ + Y+V+ L G Y F V +N +G+ P Sbjct: 16040 VSSDPKECQYIVQRLTEGHEYEFRVMAQNKYGVGPP 16075 Score = 39.9 bits (89), Expect = 0.41 Identities = 36/115 (31%), Positives = 55/115 (47%), Gaps = 15/115 (13%) Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN----LVIQDARQTDAGR 177 G++V LE RG P+P V W K+ T GD+ +D G+ ++ +++D G+ Sbjct: 17884 GESVRLEA-GLRGKPQPTVTWVKDKAT----GDNPRISIDTGHDYSKFLLTKTKRSDTGK 17938 Query: 178 YQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232 Y A N AG+ T ++ I GP + +G S T +CRV DP D Sbjct: 17939 YVVTATNPAGS-----FTAYANVTVLDIPGPVRDMKISGIS-TDKCRVAWDPPED 17987 Score = 39.5 bits (88), Expect = 0.55 Identities = 23/88 (26%), Positives = 39/88 (44%), Gaps = 4/88 (4%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL--PAGGL 66 G+ P Q V + G+P P ++W+KG + S S++ P G Sbjct: 3513 GQPPCFTTQIQPVQCVEGSEVKFQYKVTGTPFPDVQWFKGNSQIKSSQTCSVVCNPDGSG 3572 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTA 94 F + + + D+G+Y C+A N +G A Sbjct: 3573 FLIMSNIQQ--RDSGLYTCKAVNPFGEA 3598 Score = 39.5 bits (88), Expect = 0.55 Identities = 33/106 (31%), Positives = 47/106 (44%), Gaps = 10/106 (9%) Query: 506 PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565 PP KP V +SVTL W+ G I GY VE ++ L N R Sbjct: 22077 PPGKPEAVIVKRSSVTLRWTPPQFDGGIKITGYVVE---KKELP------NGRWMKASFA 22127 Query: 566 RVHQTHYVVKSLIPGITYMFIVRTENSHGLSG-PSPVSDSVTVGDD 610 + +T +VV L+ Y F V N+ G+S PS + ++T D+ Sbjct: 22128 NIIETEFVVSGLVEEQQYEFRVIARNAAGVSSVPSDSTGAITAKDE 22173 Score = 39.5 bits (88), Expect = 0.55 Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 16/135 (11%) Query: 77 HSDAGVYW---CEATNSYGTARSRNATLHVAV--LREEFRLEPESKQSAQ-----GDTVV 126 H GVY+ A N GT RS V + EE ++ + S Q G V Sbjct: 26866 HLKPGVYYYYRVSAVNCVGTGRSIEIVQPVQAKDILEEADVDLDISMSTQYIAKAGRDVE 26925 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD---GGNLVIQDARQTDAGRYQCIAR 183 + +P +G P PNV W+K + + GD+R + + L+I + D G+Y Sbjct: 26926 I-VIPLKGRPAPNVTWRKGDKNI--SGDARYAIRNTEYSTTLIIPKVTRDDTGKYLLEIE 26982 Query: 184 NAAGTRESAIATLKI 198 N G ++ ++K+ Sbjct: 26983 NGVGEPKTITVSVKV 26997 Score = 38.7 bits (86), Expect = 0.96 Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 2/86 (2%) Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGE 269 + + G S+ + G P P+V W ++ G N ++ + SL ++NV D G+ Sbjct: 22588 ITVRAGGSLRLFVPIRGRPTPEVKWGKTEGEIN-EAAQIDITSSFTSLVIENVNRFDSGK 22646 Query: 270 YSCEAENSVGAVSASGYLTVYDPPSI 295 Y+ EN+ G SA + V D P + Sbjct: 22647 YTLTLENASGTKSAFISVRVLDTPDM 22672 Score = 38.7 bits (86), Expect = 0.96 Identities = 34/107 (31%), Positives = 46/107 (42%), Gaps = 12/107 (11%) Query: 506 PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIA- 564 PP P+ VT SV L W+ G S + GY VE R+ G W+ + Sbjct: 23158 PPGTPVPVIVTRHSVKLRWTPPEYDGGSLVTGYVVE--KRDLPEGR--------WMKASF 23207 Query: 565 RRVHQTHYVVKSLIPGITYMFIVRTENSHG-LSGPSPVSDSVTVGDD 610 + +T + V LI Y F V N G +S PS + SVT D+ Sbjct: 23208 ANILETEFTVTGLIEDCKYDFRVIARNGAGSVSRPSESTGSVTAKDE 23254 Score = 38.7 bits (86), Expect = 0.96 Identities = 31/104 (29%), Positives = 46/104 (44%), Gaps = 8/104 (7%) Query: 104 AVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-- 161 A L + +P S ++GD+ C G P P V W G+T++ R+H+ Sbjct: 32133 ATLSAKILTKPHSLIVSEGDSARFVC-DIDGEPAPTVTWMHEGRTVV--SSHRIHVSTTQ 32189 Query: 162 -GGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL 204 L I +D G Y + N+ G +E A TL I+ KP L Sbjct: 32190 YKSTLEISSVEYSDEGNYTVVVENSEGKQE-ARCTLAIN-KPIL 32231 Score = 38.3 bits (85), Expect = 1.3 Identities = 53/225 (23%), Positives = 84/225 (37%), Gaps = 33/225 (14%) Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW-----SVEGN------------RTI 334 PP++ +V V G C +G P P + W +E + R + Sbjct: 741 PPTLIAGLKNVTVTEGESVTLECQISGHPTPAIMWFREDYRIENSIDFQITYEKSYARLM 800 Query: 335 IFPGMSRD--KYHATAVFDGVTVLT-----INDTDKNDSRNTIVCS---AVNYAGSSFVR 384 I + D ++ TA + T+ T + +++ +SR I V A + Sbjct: 801 IREAFAEDSGRFTCTATSEAGTISTSCYLLVKVSEEIESREEITIQEKQTVVEAKDETMS 860 Query: 385 GKLTVTSDDDRPP-PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR 443 +V+ D P P P Q L VF C +P+P I W G L +R Sbjct: 861 EISSVSVDTGAPAAPFFVKKPVVQKLVEGGSVVFVCQIGGSPKPHIYWKKSGVPLTTGYR 920 Query: 444 RNV-----TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483 V T + L + D+G YT A ++HG+ S +LL Sbjct: 921 YRVSHNKDTGECKLEISMTFADDAGEYTIFAKNQHGETSASTSLL 965 Score = 38.3 bits (85), Expect = 1.3 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 2/97 (2%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P +I +VTV + TL C+ G P+PAI W++ + + I L Sbjct: 742 PTLIAGLKNVTVTEGESVTLECQISGHPTPAIMWFREDYRIENSIDFQITYEKSYARLMI 801 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE 108 D+G + C AT+ GT S + L V V E Sbjct: 802 REA-FAEDSGRFTCTATSEAGTI-STSCYLLVKVSEE 836 Score = 38.3 bits (85), Expect = 1.3 Identities = 39/153 (25%), Positives = 69/153 (45%), Gaps = 8/153 (5%) Query: 665 FIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVA 724 ++ F+ +++ + KT L V +T L + +YEF +I GKPS + + Sbjct: 19847 YVEFKDRNSLMWKRASKTQLR---VKECRVTGLVEGLEYEFRVIAINVAGLGKPSRTTES 19903 Query: 725 QTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVA 784 D P PP ++ + +V L W+ P+ +TGY +V L+ P M A Sbjct: 19904 LVALD-PIDPPGKPDVINVTRNSVTLMWTAPKYD-GGHKLTGY--MVEKLEHPGKTWMKA 19959 Query: 785 INTTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817 + V Q+ + +T+L G + +I A+ G Sbjct: 19960 NHVNV-QSCAYTVTDLQEGCTCEFRIRAKNAAG 19991 Score = 38.3 bits (85), Expect = 1.3 Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 2/83 (2%) Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGTRESA 192 G P P+V+W K+G+ L + D L +++A + D G+Y + +N G +S Sbjct: 22205 GKPIPSVHWIKSGEELTNTARLEIKNTDFTTTLSVKEAIRVDGGQYTLLLKNVGG-EKSV 22263 Query: 193 IATLKIHIKPYLITGPEDVVAQT 215 I +K+ +P GP + T Sbjct: 22264 IINVKVLDRPGPPDGPISIYGVT 22286 Score = 38.3 bits (85), Expect = 1.3 Identities = 27/96 (28%), Positives = 41/96 (42%), Gaps = 9/96 (9%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 PGPP N++ S+T+ W++ G + I+GY VE R + + Sbjct: 23454 PGPPQDLEITNISRDSMTVCWTRPESDGGNEIVGYIVEKRDRAGIRWTKCNK-------- 23505 Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599 RRV + V L Y F + EN+ G+ PS Sbjct: 23506 -RRVTDLRFRVTGLTEDHEYEFRLSAENAAGVGQPS 23540 Score = 38.3 bits (85), Expect = 1.3 Identities = 39/132 (29%), Positives = 60/132 (45%), Gaps = 16/132 (12%) Query: 733 GPPIN-IEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQ 791 GP + +EM + +V LKW PP IT Y +V+ AN + +++ V + Sbjct: 26206 GPAVGPVEMCDITEDSVSLKWLPPAYD-GGSPITNY-IVLKRETTTAN--WIEVSSAVAR 26261 Query: 792 ATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDL---LSRYPMNGEV 848 T IM L +GV Y +I AE G+ +IDS++V + L L P V Sbjct: 26262 CTIKIM-KLNTGVEYQFRIKAENRFGISE-------HIDSQTVTVSLPYTLPVAPSQPWV 26313 Query: 849 SIVAGDFVMETW 860 S V + ++ W Sbjct: 26314 SAVTKESIVVNW 26325 Score = 38.3 bits (85), Expect = 1.3 Identities = 35/136 (25%), Positives = 60/136 (44%), Gaps = 9/136 (6%) Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSR-VAQTLDDVPDGPPINIEMFILNTTTVHL 750 F+I +L K T+Y+F + K P S V P GPP +F + + + + Sbjct: 27351 FKIPNLVKGTEYQFRVRAENKYGVSDPLTSPDVVAQHQYKPPGPPGKPVVFNVTSDGMTV 27410 Query: 751 KWSPPELQLQNGIITGYNVVVNWLDVPANKSMV--AINTTVHQATSLIMTNLTSGVSYSV 808 +W P ITGY+ L+ S++ +NT+V + L G+ YS Sbjct: 27411 QWDAPGFD-GGSPITGYH-----LEKKDRNSLLWMKVNTSVISGREYRVIGLIEGLEYSF 27464 Query: 809 QIAAETIIGLGPFSQK 824 ++ A+ G+ P S++ Sbjct: 27465 RVYAQNNAGMSPVSEQ 27480 Score = 37.9 bits (84), Expect = 1.7 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 3/91 (3%) Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LV 453 PP + G N T+ C P P I W+ E + + +T + + L+ Sbjct: 741 PPTLIAGLKNVTVTEGESVTLECQISGHPTPAIMWFREDYRIENSIDFQITYEKSYARLM 800 Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 +++ DSG +TC A+S G S LLV Sbjct: 801 IREAFAEDSGRFTCTATSEAGTISTSCYLLV 831 Score = 37.9 bits (84), Expect = 1.7 Identities = 30/110 (27%), Positives = 43/110 (39%), Gaps = 13/110 (11%) Query: 502 SLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV 561 ++PGPP P + + T L W + K G S +LGY VE + W Sbjct: 17471 TVPGPPVNPKVKDYSCTYADLVWIKPTKDGGSPVLGYIVE-----------CQKGGAEWE 17519 Query: 562 VIAR--RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 + + + Q Y VK L Y F V+ N G + +SV D Sbjct: 17520 KVNKDDLIKQCAYRVKGLTEDTEYRFRVKAVNMIGEGETREIPESVIAKD 17569 Score = 37.9 bits (84), Expect = 1.7 Identities = 36/139 (25%), Positives = 63/139 (45%), Gaps = 7/139 (5%) Query: 87 ATNSYGTARSRNATLHV----AVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW 142 ATN G + R ++ V V+ F+L + GD + ++ +P P+ V W Sbjct: 21759 ATNEKGISDPRPLSVPVIAKDVVIAPAFKLLFSTFSVLAGDDLKID-VPYVAQPKAAVVW 21817 Query: 143 KKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201 +K+G +L + + L++++A + D G+Y N+AG + I + + K Sbjct: 21818 QKDGISLKETTRVNTEVAERHLYLLLKEATRDDVGKYTIKITNSAGEATADINVIVLD-K 21876 Query: 202 PYLITGPEDVVAQTGSSVT 220 P TGP + T SVT Sbjct: 21877 PGPPTGPIKIEEVTADSVT 21895 Score = 37.9 bits (84), Expect = 1.7 Identities = 27/102 (26%), Positives = 49/102 (48%), Gaps = 3/102 (2%) Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQC 180 G + +E +P G P P V K+GQ L + ++ ++++ +DAGRY Sbjct: 26126 GSNLKIE-IPLTGKPLPKVSLSKDGQVLKSTMRFNFDVTTDSLIIYLRESVASDAGRYDI 26184 Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQ 222 A N+ GT +S + + + +P GP ++ T SV+ + Sbjct: 26185 TASNSNGTTKSFVNVVVLD-RPGPAVGPVEMCDITEDSVSLK 26225 Score = 37.9 bits (84), Expect = 1.7 Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 10/105 (9%) Query: 506 PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565 PP ++T S++L+W + + G S I GY +E+ ++ G + N Sbjct: 26405 PPNSVRVTDITKNSISLAWQKPSYDGGSKITGYLIEM--KDGPKGRWSKAN-------LT 26455 Query: 566 RVHQTHYVVKSLIPGITYMFIVRTENSHG-LSGPSPVSDSVTVGD 609 V T + V L +Y F V +N+ G +S PS + VT D Sbjct: 26456 NVTDTKFTVSGLTQNESYEFRVMAKNAVGSVSNPSEIVGPVTCVD 26500 Score = 37.9 bits (84), Expect = 1.7 Identities = 26/85 (30%), Positives = 40/85 (47%), Gaps = 4/85 (4%) Query: 111 RLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGD--SRMHLVDGGNLVIQ 168 +L E+ G +VL+ G PEP V+W K G L G+ S + +I+ Sbjct: 28683 KLVGETISIRAGSDLVLDAAVG-GKPEPKVFWAK-GDKELDPGEKYSLTYTSTRAMAIIK 28740 Query: 169 DARQTDAGRYQCIARNAAGTRESAI 193 + D GRY +NA+G + SA+ Sbjct: 28741 SCDRNDTGRYILTVKNASGIKTSAV 28765 Score = 37.9 bits (84), Expect = 1.7 Identities = 25/97 (25%), Positives = 45/97 (46%), Gaps = 9/97 (9%) Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP------LGRVKVLD 253 + P + PED+ +TG +T C G+P P + W R GG +P ++ + Sbjct: 32660 LAPRIEALPEDISVETGKVLTVACAFSGEPAPHIEWSR--GGKKLPGEEDSSRFHIETTE 32717 Query: 254 D-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 D +L + V D G Y+ + N G+ A+ +++ Sbjct: 32718 DLTTLIITGVKETDAGAYTLKLSNEHGSDLATVTISI 32754 Score = 37.5 bits (83), Expect = 2.2 Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 2/70 (2%) Query: 134 GSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192 G P P V WKK+G L L +G V +L + + ++G Y A N +G++ SA Sbjct: 18990 GKPMPKVVWKKDGAPLKLAEGMKMTQKVHHLSLELFSVTRKESGEYTITAENPSGSK-SA 19048 Query: 193 IATLKIHIKP 202 LK+ KP Sbjct: 19049 NIKLKVLDKP 19058 Score = 37.5 bits (83), Expect = 2.2 Identities = 17/46 (36%), Positives = 26/46 (56%) Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEV 542 A D PG P P + T TSV+L+WS + G +++ GY +E+ Sbjct: 29659 AMDPIEPPGIPLNPRVTDTTRTSVSLAWSPPEEEGGAAVTGYLIEM 29704 Score = 37.1 bits (82), Expect = 2.9 Identities = 40/150 (26%), Positives = 60/150 (40%), Gaps = 11/150 (7%) Query: 712 KKFEGKPSNSRVAQTLD-DVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVV 770 K G+ + + + LD P G P + E L + L W PE IT Y + Sbjct: 16266 KNAGGERKKAVIVEVLDVPGPVGLPFSGEN--LTNDSCKLTWYSPEDD-GGSAITNYIIE 16322 Query: 771 VNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNID 830 D S V T H A ++ L G Y +IAAE IIG+GPF++ + Sbjct: 16323 KREADRRGWTS-VTYTVTRHNA---VVQGLIDGKGYFFRIAAENIIGMGPFTETAAPVVI 16378 Query: 831 SRSVGLDLLSRYPMNGEVSIVAGDFVMETW 860 + + P + EV+ + D + W Sbjct: 16379 KDPLS---VPERPEDVEVTAITNDSISVAW 16405 Score = 37.1 bits (82), Expect = 2.9 Identities = 31/134 (23%), Positives = 53/134 (39%), Gaps = 7/134 (5%) Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250 S + + I+P + T Q G + + R+ G P P + W + G RV Sbjct: 22854 SPVVAKDLAIEPTVRTKLSTYSVQVGYDLKIEARISGHPKPTITWNKD-GSALKQTTRVN 22912 Query: 251 VLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP---NSVNV 304 V D +L + + D G Y+ N +G A+ + + + P P + V+ Sbjct: 22913 VADTAHHTTLTIKDATREDGGMYNIVVANVLGQQEATVEIIILEKPGPPTGPVRIDEVSA 22972 Query: 305 ESGNVARFTCTATG 318 ES ++ T TG Sbjct: 22973 ESITLSWDPPTYTG 22986 Score = 37.1 bits (82), Expect = 2.9 Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 5/75 (6%) Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPG-MSRDKYHATAVFD 351 P I P ++VE+G V C +G P P + WS G + PG ++H D Sbjct: 32662 PRIEALPEDISVETGKVLTVACAFSGEPAPHIEWSRGGKK---LPGEEDSSRFHIETTED 32718 Query: 352 GVTVLTINDTDKNDS 366 +T L I + D+ Sbjct: 32719 -LTTLIITGVKETDA 32732 Score = 36.7 bits (81), Expect = 3.9 Identities = 31/142 (21%), Positives = 53/142 (37%), Gaps = 8/142 (5%) Query: 160 VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI--------TGPEDV 211 + G V+ ++ R++ A NAAG E I +K I T E + Sbjct: 16143 IRGTKFVVPGLKELGLYRFRVRAVNAAGVGEPGEVADVIEVKDRTIPPEVDLDATVKEKI 16202 Query: 212 VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYS 271 V G + V G P P+++W R +L + + + +G Y+ Sbjct: 16203 VVHAGGVIRILAYVSGKPAPEIIWNRDDAELPKEAAVETTSISSALVIKSCLRQHQGIYT 16262 Query: 272 CEAENSVGAVSASGYLTVYDPP 293 A+N+ G + + V D P Sbjct: 16263 LTAKNAGGERKKAVIVEVLDVP 16284 Score = 36.7 bits (81), Expect = 3.9 Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 9/96 (9%) Query: 499 DVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558 D + P PP+ P + T S++++W++ G S + GY VE+ T + Sbjct: 28970 DPTYTPAPPSVPRITDTTKHSISMTWTRPMYDGGSDVTGYIVEILEEGT---------EQ 29020 Query: 559 GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHG 594 + + + T Y V L Y F V N+ G Sbjct: 29021 WYRATQKTLTSTQYTVTGLASNKKYSFRVAAVNAMG 29056 Score = 36.7 bits (81), Expect = 3.9 Identities = 28/109 (25%), Positives = 46/109 (42%), Gaps = 11/109 (10%) Query: 500 VSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRG 559 V +P P + T ++V L W + G S + G+ +E T R Sbjct: 29263 VCEVPSVPQDLYLIDTTKSTVILGWEKPLHDGGSRLSGFVIEACK------TGTDR---- 29312 Query: 560 WVVIAR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607 W+ +A + + + SL Y+F +R ENS G+S P + VT+ Sbjct: 29313 WMNVAHVKSSVLQHTIVSLTENEQYLFRIRAENSRGVSEPRDLMTPVTI 29361 Score = 36.3 bits (80), Expect = 5.1 Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 2/69 (2%) Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQ 179 +G++V LEC G P P + W + + D ++ L+I++A D+GR+ Sbjct: 755 EGESVTLEC-QISGHPTPAIMWFREDYRIENSIDFQITYEKSYARLMIREAFAEDSGRFT 813 Query: 180 CIARNAAGT 188 C A + AGT Sbjct: 814 CTATSEAGT 822 Score = 36.3 bits (80), Expect = 5.1 Identities = 29/101 (28%), Positives = 46/101 (45%), Gaps = 8/101 (7%) Query: 717 KPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDV 776 K S +A+ D P G P+ + I+ +V L+W+PPE ++TGY VV D+ Sbjct: 23145 KTSEGCIARDPCD-PPGTPVPV---IVTRHSVKLRWTPPEYD-GGSLVTGY--VVEKRDL 23197 Query: 777 PANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817 P + M A + + T +T L Y ++ A G Sbjct: 23198 PEGRWMKASFANILE-TEFTVTGLIEDCKYDFRVIARNGAG 23237 Score = 36.3 bits (80), Expect = 5.1 Identities = 37/140 (26%), Positives = 61/140 (43%), Gaps = 12/140 (8%) Query: 688 DVSGFEITSLRKYTKYEFFLIPFYKKFEGKP--SNSRVAQTLDDVPDGPPINIEMFILNT 745 + F T L K +Y+F + K GKP S+ +AQ VPD P + + Sbjct: 27739 EACSFNATKLIKGNEYQFRVSAVNKFGVGKPLESDPIIAQMQYTVPDAPGTP-DCTHVTG 27797 Query: 746 TTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLI---MTNLTS 802 ++ L W+ P +G G + L+ KS+ + + + + + +TNLT Sbjct: 27798 NSITLCWTRPR---HDG---GNEIKQYILERREKKSLRWVKVSAKRPITELRHRVTNLTE 27851 Query: 803 GVSYSVQIAAETIIGLGPFS 822 G Y ++ AE G+GP S Sbjct: 27852 GNEYEFRVMAENGAGIGPAS 27871 Score = 36.3 bits (80), Expect = 5.1 Identities = 27/104 (25%), Positives = 41/104 (39%), Gaps = 11/104 (10%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 P P + + T T+ +L W + G S I GY VE + S W V Sbjct: 28178 PASPKRLDVIDTTSTTASLVWMKPEHDGGSRITGYIVE----------TRKKGSANW-VF 28226 Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607 + V++ L+ Y F V+ +N G+S P SV + Sbjct: 28227 GGQTKSLKMVLEGLVENTEYEFRVKAQNDAGISQPRDALASVII 28270 Score = 35.9 bits (79), Expect = 6.7 Identities = 29/93 (31%), Positives = 38/93 (40%), Gaps = 10/93 (10%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 PGP +V S LSW G + I + VE ++ S P+ WV I Sbjct: 16979 PGPVQHLRVSDVRSDSAQLSWKDPEDNGGARITNFVVE--KKDAAS----PQ----WVPI 17028 Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596 + + K LI G +YMF V EN G S Sbjct: 17029 CSSSKKRSMMAKHLIEGTSYMFRVAAENQFGRS 17061 Score = 35.9 bits (79), Expect = 6.7 Identities = 25/96 (26%), Positives = 38/96 (39%), Gaps = 10/96 (10%) Query: 500 VSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRG 559 V PGPP I + V+++W G S + Y VE E + Sbjct: 19454 VLDTPGPPVNLIVKETSKDHVSITWDAPLIDGGSPVKSYVVEKRLAE----------RKA 19503 Query: 560 WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGL 595 W +A +T + + +L G Y F V EN +G+ Sbjct: 19504 WTCVAPECPKTSFRITNLEAGQAYCFRVLAENIYGI 19539 Score = 35.9 bits (79), Expect = 6.7 Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 5/85 (5%) Query: 733 GPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQA 792 GPP I++ ++ + L W PP + +G N VV D + ++ TV + Sbjct: 25124 GPPGAIKVEEISADFISLSWDPP---IYDGGCQINNYVVEKRDTTTTAWQI-VSATVAR- 25178 Query: 793 TSLIMTNLTSGVSYSVQIAAETIIG 817 TS+ ++ LT G Y +IAAE G Sbjct: 25179 TSIKVSRLTQGTEYQFRIAAENRYG 25203 Score = 35.9 bits (79), Expect = 6.7 Identities = 38/155 (24%), Positives = 64/155 (41%), Gaps = 17/155 (10%) Query: 178 YQCIARNAAG-----TRESAIATLKIHIKPYLITGPED----VVAQTGSSVTFQCRVGGD 228 ++ IA+NAAG + + T+K + P IT + VV + G + + G Sbjct: 25392 FRIIAKNAAGLFSEPSESTGPVTVKDDVDPPRITIEDKLRQLVVIKAGEILRIDAEISGR 25451 Query: 229 PLPDVLWRRSAGGGNMPLGRVKV---LDDGSLRLDNVILADEGEYSCEAENSVGAVSASG 285 P+P + W + G R ++ L +L + + I D G+Y +N G S + Sbjct: 25452 PIPVISWAKD-GKEIEAKARFEISSTLTSTTLIVRDAIRRDSGQYVLTLQNVAGTRSLAV 25510 Query: 286 YLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320 V D P P+S ++ + CT T P Sbjct: 25511 NCKVLDRP----GPSSGPLDITGLTAEKCTLTWGP 25541 Score = 35.5 bits (78), Expect = 8.9 Identities = 25/98 (25%), Positives = 40/98 (40%), Gaps = 11/98 (11%) Query: 501 SSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGW 560 S P P I +V+ + TL+W++ G S I GY +E ++S W Sbjct: 20598 SQAPSAPDDLIVTDVSKDTATLAWTKPKHDGGSRITGYVIEA----------QLKDSDQW 20647 Query: 561 VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598 + + Y+ L+ Y+F + NS G S P Sbjct: 20648 AHVT-TIKALDYIATELVENAEYVFRIFAVNSSGRSEP 20684 Score = 35.5 bits (78), Expect = 8.9 Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 6/82 (7%) Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGLFFLRATH 73 E +T+ + L+C G P P + WYK G V + +++ + LF A Sbjct: 27596 EAEKSLTIKAGENIKLSCSISGRPVPQVTWYKDGKEVDKMLVDITTVIGSSSLFIRDA-- 27653 Query: 74 GRVHSDAGVYWCEATNSYGTAR 95 R H G+Y EA NS GT + Sbjct: 27654 DRNH--RGIYTVEAKNSSGTTK 27673 Score = 35.5 bits (78), Expect = 8.9 Identities = 21/81 (25%), Positives = 36/81 (44%), Gaps = 3/81 (3%) Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN-DGTLVLK- 455 P IT + +P F P+ I W+ G+ + ++H+ TN G L L+ Sbjct: 31919 PRITVRMRSHRVPCGQNTKFTLNVQSKPDANIQWFHNGQQIQESHKYQFTNMSGVLSLQI 31978 Query: 456 -DLDKSDSGTYTCVASSRHGK 475 D D+GTY + ++ G+ Sbjct: 31979 NDCQAEDTGTYRALCTNSKGE 31999 >UniRef50_UPI0000D576E1 Cluster: PREDICTED: similar to CG12002-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG12002-PA, isoform A - Tribolium castaneum Length = 1388 Score = 151 bits (367), Expect = 9e-35 Identities = 95/285 (33%), Positives = 148/285 (51%), Gaps = 17/285 (5%) Query: 11 APYIIEQPLDVTVARHQPA-TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 +P + P+ VT + P+ +L+C+A G+P P I W + G+ + + + R + G + Sbjct: 335 SPVFLVTPVSVTTSESDPSVSLHCKAFGNPHPTITWSRNGIQLTT-SQRHFIDEDGTLVI 393 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLE 128 R SD G Y C+ATNS G S + ++VA + F + P++ ++ G T+ LE Sbjct: 394 RPVKA---SDHGTYRCDATNSNGRISSEADVIVNVAPV---FTVHPQNTETTPGSTIKLE 447 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188 C GSP P + W K+ + DG + DG +L I +A++TD+G Y C ARN G Sbjct: 448 CFAV-GSPPPEITWFKDDLEVRSDGRLSIS-PDGSSLQIHNAKETDSGLYICEARNHLGF 505 Query: 189 RESAIATLKI----HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 RE + A +K+ P I P ++ A GS++ C+ GDP P + W++ G Sbjct: 506 REVS-AKVKVTPLARKPPKFIYKPYNIEALVGSTIELPCKADGDPTPGIQWQKD-GASLQ 563 Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 GR KV G+L + V+ D+G Y C A N G +AS Y+TV Sbjct: 564 RTGRTKVSLIGNLYIYGVVPDDQGRYECAAINDFGRSTASCYVTV 608 Score = 146 bits (353), Expect = 4e-33 Identities = 106/390 (27%), Positives = 177/390 (45%), Gaps = 28/390 (7%) Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT 173 P+ + + G T V C G P+P++YW ++ + + + D + ++D G+LVI+ ++ Sbjct: 240 PQDVEISWGSTAVFTCRVT-GDPKPSIYWMRDDKEIEMNND-KYDIMDNGSLVIKHTDES 297 Query: 174 DAGRYQCIARNAAGTRESAIATLKIHIKP------------YLITGPEDVVAQTGSSVTF 221 D+G Y+C+A+N G +S A + I ++P +L+T +++ SV+ Sbjct: 298 DSGHYECMAKNEDGEVKSRPARM-ILVRPDQQFRGGNGSPVFLVTPVSVTTSESDPSVSL 356 Query: 222 QCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVGA 280 C+ G+P P + W R+ G + + +D DG+L + V +D G Y C+A NS G Sbjct: 357 HCKAFGNPHPTITWSRN--GIQLTTSQRHFIDEDGTLVIRPVKASDHGTYRCDATNSNGR 414 Query: 281 VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340 +S+ + V P + P + G+ + C A G P P + W + Sbjct: 415 ISSEADVIVNVAPVFTVHPQNTETTPGSTIKLECFAVGSPPPEITWFKDDLEV------- 467 Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII 400 R + DG + L I++ + DS +C A N+ G V K+ VT +PP I Sbjct: 468 RSDGRLSISPDGSS-LQIHNAKETDS-GLYICEARNHLGFREVSAKVKVTPLARKPPKFI 525 Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS 460 P N + S PC A P P I W +G +L + R V+ G L + + Sbjct: 526 YK-PYNIEALVGSTIELPCKADGDPTPGIQWQKDGASLQRTGRTKVSLIGNLYIYGVVPD 584 Query: 461 DSGTYTCVASSRHGKYVWSGALLVDSPINP 490 D G Y C A + G+ S + V NP Sbjct: 585 DQGRYECAAINDFGRSTASCYVTVKENQNP 614 Score = 139 bits (336), Expect = 5e-31 Identities = 99/337 (29%), Positives = 156/337 (46%), Gaps = 25/337 (7%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 +AP I+E P DV ++ A CR G P P+I W + + + + + G + Sbjct: 232 KAPEIMEGPQDVEISWGSTAVFTCRVTGDPKPSIYWMRDDKEIEMNNDKYDIMDNGSLVI 291 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR---------LEPESKQSA 120 + T SD+G Y C A N G +SR A + + ++FR + P S ++ Sbjct: 292 KHTD---ESDSGHYECMAKNEDGEVKSRPARMILVRPDQQFRGGNGSPVFLVTPVSVTTS 348 Query: 121 QGD-TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRY 178 + D +V L C G+P P + W +NG L S+ H +D G LVI+ + +D G Y Sbjct: 349 ESDPSVSLHC-KAFGNPHPTITWSRNGIQLT---TSQRHFIDEDGTLVIRPVKASDHGTY 404 Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238 +C A N+ G R S+ A + +++ P P++ GS++ +C G P P++ W + Sbjct: 405 RCDATNSNG-RISSEADVIVNVAPVFTVHPQNTETTPGSTIKLECFAVGSPPPEITWFKD 463 Query: 239 AGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVG--AVSASGYLT--VYDPP 293 GR+ + DG SL++ N D G Y CEA N +G VSA +T PP Sbjct: 464 DLEVRSD-GRLSISPDGSSLQIHNAKETDSGLYICEARNHLGFREVSAKVKVTPLARKPP 522 Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330 P ++ G+ C A G P P + W +G Sbjct: 523 KFIYKPYNIEALVGSTIELPCKADGDPTPGIQWQKDG 559 Score = 99.5 bits (237), Expect = 5e-19 Identities = 83/296 (28%), Positives = 124/296 (41%), Gaps = 29/296 (9%) Query: 193 IATLKIHIK-PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251 + T H K P ++ GP+DV GS+ F CRV GDP P + W R M + + Sbjct: 224 MTTRDFHCKAPEIMEGPQDVEISWGSTAVFTCRVTGDPKPSIYWMRDDKEIEMNNDKYDI 283 Query: 252 LDDGSLRLDNVILADEGEYSCEAENSVGAV-SASGYLTVYDP----------PSINLSPN 300 +D+GSL + + +D G Y C A+N G V S + + P P ++P Sbjct: 284 MDNGSLVIKHTDESDSGHYECMAKNEDGEVKSRPARMILVRPDQQFRGGNGSPVFLVTPV 343 Query: 301 SVNV-ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359 SV ES C A G P PT+ WS G + ++ + H D L I Sbjct: 344 SVTTSESDPSVSLHCKAFGNPHPTITWSRNGIQ------LTTSQRH---FIDEDGTLVIR 394 Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419 +D T C A N G + V P+ T P N S C Sbjct: 395 PVKASD-HGTYRCDATNSNGRISSEADVIV-----NVAPVFTVHPQNTETTPGSTIKLEC 448 Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474 A+ +P P I W+ + + + R +++ DG +L + + ++DSG Y C A + G Sbjct: 449 FAVGSPPPEITWFKDDLEVRSDGRLSISPDGSSLQIHNAKETDSGLYICEARNHLG 504 Score = 78.6 bits (185), Expect = 1e-12 Identities = 58/190 (30%), Positives = 89/190 (46%), Gaps = 16/190 (8%) Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352 P I P V + G+ A FTC TG P+P+++W + ++ I M+ DKY + D Sbjct: 234 PEIMEGPQDVEISWGSTAVFTCRVTGDPKPSIYW-MRDDKEI---EMNNDKYD---IMDN 286 Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR-GKLTVTSDDDR-----PPPIITNGPSN 406 + L I TD++DS + C A N G R ++ + D + P+ P + Sbjct: 287 GS-LVIKHTDESDSGH-YECMAKNEDGEVKSRPARMILVRPDQQFRGGNGSPVFLVTPVS 344 Query: 407 QTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465 T +V C A P P I W G L + R + DGTLV++ + SD GTY Sbjct: 345 VTTSESDPSVSLHCKAFGNPHPTITWSRNGIQLTTSQRHFIDEDGTLVIRPVKASDHGTY 404 Query: 466 TCVASSRHGK 475 C A++ +G+ Sbjct: 405 RCDATNSNGR 414 >UniRef50_Q4RJ21 Cluster: Chromosome 1 SCAF15039, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1 SCAF15039, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1702 Score = 151 bits (366), Expect = 1e-34 Identities = 144/487 (29%), Positives = 215/487 (44%), Gaps = 49/487 (10%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG-GLFFLRATHGRVHS 78 +V++ Q +L C GSPSP I WYK + VV+ + IL G L L+A + Sbjct: 1115 NVSLVLSQSTSLVCDVTGSPSPVITWYKEEMPVVASDNVQILDMGKTLRLLKAD----PA 1170 Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG-DTVV-------LECL 130 D+G Y C+A N G+A VAVL + P K S DTV LEC Sbjct: 1171 DSGSYSCKAVNIAGSAEK---GFFVAVL-----VPPTIKGSGSSHDTVAMVTQEISLEC- 1221 Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTR 189 G P P + W K+ + +F GD + + + G ++ I+ AR D RYQC N AG + Sbjct: 1222 KVEGLPFPTIQWYKD-RKQVFLGDPNLEVTNRGQILRIKSARLGDKARYQCSVMNTAG-K 1279 Query: 190 ESAIATLKIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247 ES L +H+ P + G V A G+ VT +C G P P V W R+ G + Sbjct: 1280 ESRDFNLSVHVPPTIKGGNASTGVTALLGTVVTLECEGRGVPPPTVTWYRN-GQAILSGR 1338 Query: 248 RVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI---NLSPNSVN 303 + + + G L++ V D G Y+C+A + VG+ + L VY PP+I + P Sbjct: 1339 QTQYTERGRFLKILRVQATDAGRYTCKAASVVGSTEKTFELDVYLPPTIKGDDAGPTERK 1398 Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363 V C A GRP P++ W + G+ + V + + I+ Sbjct: 1399 VVLSASLILECEAGGRPPPSLTW--------LKDGVPVRHSQSLRVLELGGKIEISSATL 1450 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP--SNQTLPIKSMAVFPCTA 421 +DS VC A + AG V+ +TV PP I ++ T+ I C A Sbjct: 1451 SDS-GRYVCVATSVAGEKEVKYDVTVL-----VPPFIQGAGVITHSTVIINHPLEMECQA 1504 Query: 422 ICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480 TP P++ WY +G+ + Q V G L++ SD+ + CVA++ G Sbjct: 1505 TGTPTPVVTWYKDGKPIQQGEGWRVAAGGQRLLVSRAQISDTARFQCVAANEAGDIQRDF 1564 Query: 481 ALLVDSP 487 ++V P Sbjct: 1565 TVVVHEP 1571 Score = 131 bits (316), Expect = 1e-28 Identities = 133/476 (27%), Positives = 196/476 (41%), Gaps = 33/476 (6%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLFF 68 E P+ PL VA +Q C A G P P IRW + G L ++ SIL G L Sbjct: 1014 EPPF--NSPLQERVA-NQRIAFPCPAKGLPKPVIRWLRNGQELTGNEPGVSILEDGTLLL 1070 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS-AQGDTVVL 127 L + D+G Y C A N G+ R L V V + E S + L Sbjct: 1071 LASVS---PLDSGEYVCAAANDAGST-ERKYQLKVNVPPDFTDNEVSRNVSLVLSQSTSL 1126 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 C GSP P + W K ++ D+ L G L + A D+G Y C A N AG Sbjct: 1127 VC-DVTGSPSPVITWYKEEMPVV-ASDNVQILDMGKTLRLLKADPADSGSYSCKAVNIAG 1184 Query: 188 TRESAIATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 + E + + + P + D VA ++ +C+V G P P + W + + Sbjct: 1185 SAEKGF-FVAVLVPPTIKGSGSSHDTVAMVTQEISLECKVEGLPFPTIQWYKDRKQVFLG 1243 Query: 246 LGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304 ++V + G LR+ + L D+ Y C N+ G S L+V+ PP+I S V Sbjct: 1244 DPNLEVTNRGQILRIKSARLGDKARYQCSVMNTAGKESRDFNLSVHVPPTIKGGNASTGV 1303 Query: 305 ES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362 + G V C G P PT+ W G I G + +Y F + +L + TD Sbjct: 1304 TALLGTVVTLECEGRGVPPPTVTWYRNGQ--AILSG-RQTQYTERGRF--LKILRVQATD 1358 Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN--GPSNQTLPIKSMAVFPCT 420 R T C A + GS+ + T D PP I + GP+ + + + + + C Sbjct: 1359 A--GRYT--CKAASVVGST----EKTFELDVYLPPTIKGDDAGPTERKVVLSASLILECE 1410 Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTN-DGTLVLKDLDKSDSGTYTCVASSRHGK 475 A P P + W +G + + V G + + SDSG Y CVA+S G+ Sbjct: 1411 AGGRPPPSLTWLKDGVPVRHSQSLRVLELGGKIEISSATLSDSGRYVCVATSVAGE 1466 Score = 131 bits (316), Expect = 1e-28 Identities = 129/479 (26%), Positives = 194/479 (40%), Gaps = 38/479 (7%) Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85 Q +L C+ G P P I+WYK V + D + + G + LR R+ D Y C Sbjct: 1215 QEISLECKVEGLPFPTIQWYKDRKQVFLGDPNLEVTNRGQI--LRIKSARL-GDKARYQC 1271 Query: 86 EATNSYGT-ARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK 144 N+ G +R N ++HV + + G V LEC RG P P V W + Sbjct: 1272 SVMNTAGKESRDFNLSVHVPPTIKGGNAST-GVTALLGTVVTLEC-EGRGVPPPTVTWYR 1329 Query: 145 NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL 204 NGQ +L G + G L I + TDAGRY C A + G+ E L +++ P + Sbjct: 1330 NGQAIL-SGRQTQYTERGRFLKILRVQATDAGRYTCKAASVVGSTEKTFE-LDVYLPPTI 1387 Query: 205 I---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLD 260 GP + +S+ +C GG P P + W + G ++VL+ G + + Sbjct: 1388 KGDDAGPTERKVVLSASLILECEAGGRPPPSLTWLKD-GVPVRHSQSLRVLELGGKIEIS 1446 Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVNVESGNVARFTCTATG 318 + L+D G Y C A + G +TV PP I + V + C ATG Sbjct: 1447 SATLSDSGRYVCVATSVAGEKEVKYDVTVLVPPFIQGAGVITHSTVIINHPLEMECQATG 1506 Query: 319 RPEPTMFWSVEGNRTIIFPG-----------MSRDKYHATAVFDGVTVLTINDTDKNDSR 367 P P + W +G G +SR + TA F V D ++ + Sbjct: 1507 TPTPVVTWYKDGKPIQQGEGWRVAAGGQRLLVSRAQISDTARFQCVAANEAGDIQRDFTV 1566 Query: 368 NTIVCSAVNYAGS----SFVRGKLT-----VTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418 +V +AG + + G T T PP+I++ T+ + A Sbjct: 1567 VVHEPPSVPHAGDVINQTILAGFSTQLECKATGTPLPVPPVISSQGGTVTVLVNEPARLE 1626 Query: 419 CTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGK 475 C A P P W +G + H V ++G L L +D+GTYTCVA + G+ Sbjct: 1627 CEATGVPSPSFTWLKDGSPVASVPHGLQVLSEGRALSLNSALVTDTGTYTCVAVNAGGE 1685 Score = 120 bits (289), Expect = 2e-25 Identities = 120/434 (27%), Positives = 175/434 (40%), Gaps = 37/434 (8%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD---THRSILPAG-GL 66 AP +P D TL C G P P + W + L + T+ S+ + GL Sbjct: 593 APEFTREPSDTASDIGSNVTLWCLVRGYPDPQVTWRRQDGLPPFNRPRTYGSVTQSRRGL 652 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126 F TH V +A VY CEA N +G ++ ++ P + V Sbjct: 653 HF---THLWVEDEA-VYVCEAHNHFGKIEAKARITVTGLVLPVIARSPSVLSVVEDQPVT 708 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186 L C+ G+P P W N L D + + G+L I+ R G Y C+A N Sbjct: 709 LPCVLLAGNPLPARQWLHNYG--LVTTDQYVKVRKDGSLHIERVRLDHVGDYTCLAENVV 766 Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 G TL +++ P + GP+ G+ VT CR G P P++ W + G + L Sbjct: 767 GLYNHT-TTLNVYVIPTIQHGPQVFNTIEGTPVTLPCRAIGVPSPEITWTKE--GKLLYL 823 Query: 247 GRVK-VLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-------DPPSINL 297 G LD DGSL +++ + GE+ C A N+ G S LTVY + P + Sbjct: 824 GGPDFFLDSDGSLFINSPSGNESGEFICMATNAAGHASRRVQLTVYVRPRSNAEGPGSSA 883 Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 P ++V G A C P PT+ W+ E +I P R +H + Sbjct: 884 EPLRMSVTEGEDAILPCEVHSVPPPTITWAKE---RLISPFAPR--HHPLPSCS----MK 934 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417 I ++ +DS VC A N AG+ + L+V PP I GP + + Sbjct: 935 ILESKVSDS-GIYVCVASNIAGNLTLSVLLSVL-----VPPSIQPGPRVMKVQVGHPVEL 988 Query: 418 PCTAICTPEPIIAW 431 PC PEP + W Sbjct: 989 PCMVSGVPEPTLTW 1002 Score = 119 bits (287), Expect = 4e-25 Identities = 114/385 (29%), Positives = 154/385 (40%), Gaps = 17/385 (4%) Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LV 166 EF EP S G V L CL RG P+P V W++ F+ V L Sbjct: 595 EFTREPSDTASDIGSNVTLWCLV-RGYPDPQVTWRRQDGLPPFNRPRTYGSVTQSRRGLH 653 Query: 167 IQDARQTDAGRYQCIARNAAGTRES-AIATLKIHIKPYLITGPEDVVAQTGSSVTFQC-R 224 D Y C A N G E+ A T+ + P + P + VT C Sbjct: 654 FTHLWVEDEAVYVCEAHNHFGKIEAKARITVTGLVLPVIARSPSVLSVVEDQPVTLPCVL 713 Query: 225 VGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSAS 284 + G+PLP W + G VKV DGSL ++ V L G+Y+C AEN VG + + Sbjct: 714 LAGNPLPARQWLHNYGLVTTDQ-YVKVRKDGSLHIERVRLDHVGDYTCLAENVVGLYNHT 772 Query: 285 GYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344 L VY P+I P N G C A G P P + W+ EG +++ G D + Sbjct: 773 TTLNVYVIPTIQHGPQVFNTIEGTPVTLPCRAIGVPSPEITWTKEGK--LLYLG-GPDFF 829 Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT--VTSDDDRPPPIITN 402 D L IN N+S +C A N AG + R +LT V + P + Sbjct: 830 -----LDSDGSLFINSPSGNES-GEFICMATNAAGHASRRVQLTVYVRPRSNAEGPGSSA 883 Query: 403 GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDS 462 P ++ A+ PC P P I W E R + ++ + + SDS Sbjct: 884 EPLRMSVTEGEDAILPCEVHSVPPPTITWAKERLISPFAPRHHPLPSCSMKILESKVSDS 943 Query: 463 GTYTCVASSRHGKYVWSGALLVDSP 487 G Y CVAS+ G S L V P Sbjct: 944 GIYVCVASNIAGNLTLSVLLSVLVP 968 Score = 119 bits (286), Expect = 6e-25 Identities = 98/330 (29%), Positives = 140/330 (42%), Gaps = 18/330 (5%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNC-RAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64 VT P I P ++V QP TL C G+P PA +W LV +D + + G Sbjct: 684 VTGLVLPVIARSPSVLSVVEDQPVTLPCVLLAGNPLPARQWLHNYGLVTTDQYVKVRKDG 743 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124 L R V G Y C A N G + TL+V V+ + P+ + +G Sbjct: 744 SLHIERVRLDHV----GDYTCLAENVVGLY-NHTTTLNVYVI-PTIQHGPQVFNTIEGTP 797 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 V L C G P P + W K G+ LL+ G L G+L I ++G + C+A N Sbjct: 798 VTLPCRAI-GVPSPEITWTKEGK-LLYLGGPDFFLDSDGSLFINSPSGNESGEFICMATN 855 Query: 185 AAGTRESAIATLKIHIKPYL-ITGPEDVVAQTGSSVT------FQCRVGGDPLPDVLWRR 237 AAG S L ++++P GP SVT C V P P + W + Sbjct: 856 AAG-HASRRVQLTVYVRPRSNAEGPGSSAEPLRMSVTEGEDAILPCEVHSVPPPTITWAK 914 Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297 R L S+++ ++D G Y C A N G ++ S L+V PPSI Sbjct: 915 ERLISPFA-PRHHPLPSCSMKILESKVSDSGIYVCVASNIAGNLTLSVLLSVLVPPSIQP 973 Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWS 327 P + V+ G+ C +G PEPT+ W+ Sbjct: 974 GPRVMKVQVGHPVELPCMVSGVPEPTLTWT 1003 Score = 116 bits (279), Expect = 4e-24 Identities = 105/380 (27%), Positives = 161/380 (42%), Gaps = 32/380 (8%) Query: 103 VAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG 162 V VL F + + + Q + C P +G P+P + W +NGQ L + L DG Sbjct: 1010 VEVLEPPFNSPLQERVANQ--RIAFPC-PAKGLPKPVIRWLRNGQELTGNEPGVSILEDG 1066 Query: 163 GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG--PEDVVAQTGSSVT 220 L++ D+G Y C A N AG+ E LK+++ P +V S + Sbjct: 1067 TLLLLASVSPLDSGEYVCAAANDAGSTERKY-QLKVNVPPDFTDNEVSRNVSLVLSQSTS 1125 Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDG-SLRLDNVILADEGEYSCEAEN 276 C V G P P + W + MP+ V++LD G +LRL AD G YSC+A N Sbjct: 1126 LVCDVTGSPSPVITWYKE----EMPVVASDNVQILDMGKTLRLLKADPADSGSYSCKAVN 1181 Query: 277 SVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT--CTATGRPEPTMFWSVEGNRTI 334 G+ ++ V PP+I S +S + + + C G P PT+ W + R Sbjct: 1182 IAGSAEKGFFVAVLVPPTIKGSGSSHDTVAMVTQEISLECKVEGLPFPTIQWYKD--RKQ 1239 Query: 335 IFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394 +F G V + +L I D + CS +N AG L+V Sbjct: 1240 VFLGDPN-----LEVTNRGQILRIKSARLGD-KARYQCSVMNTAGKESRDFNLSV----- 1288 Query: 395 RPPPIITNGPSNQ--TLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT- 451 PP I G ++ T + ++ C P P + WY G+A++ + T G Sbjct: 1289 HVPPTIKGGNASTGVTALLGTVVTLECEGRGVPPPTVTWYRNGQAILSGRQTQYTERGRF 1348 Query: 452 LVLKDLDKSDSGTYTCVASS 471 L + + +D+G YTC A+S Sbjct: 1349 LKILRVQATDAGRYTCKAAS 1368 Score = 105 bits (253), Expect = 6e-21 Identities = 84/337 (24%), Positives = 144/337 (42%), Gaps = 15/337 (4%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80 VT TL C G P P + WY+ G ++S G FL+ + +DA Sbjct: 1303 VTALLGTVVTLECEGRGVPPPTVTWYRNGQAILSGRQTQYTERGR--FLKILRVQA-TDA 1359 Query: 81 GVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139 G Y C+A + G T ++ +++ + P ++ +++LEC G P P+ Sbjct: 1360 GRYTCKAASVVGSTEKTFELDVYLPPTIKGDDAGPTERKVVLSASLILEC-EAGGRPPPS 1418 Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199 + W K+G + R+ L GG + I A +D+GRY C+A + AG +E + + Sbjct: 1419 LTWLKDGVPVRHSQSLRV-LELGGKIEISSATLSDSGRYVCVATSVAGEKEVKY-DVTVL 1476 Query: 200 IKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS 256 + P+ I G + T + +C+ G P P V W + G Sbjct: 1477 VPPF-IQGAGVITHSTVIINHPLEMECQATGTPTPVVTWYKDGKPIQQGEGWRVAAGGQR 1535 Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN--VESGNVARFTC 314 L + ++D + C A N G + + V++PPS+ + + +N + +G + C Sbjct: 1536 LLVSRAQISDTARFQCVAANEAGDIQRDFTVVVHEPPSVPHAGDVINQTILAGFSTQLEC 1595 Query: 315 TATGR--PEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349 ATG P P + S G T++ +R + AT V Sbjct: 1596 KATGTPLPVPPVISSQGGTVTVLVNEPARLECEATGV 1632 Score = 92.7 bits (220), Expect = 6e-17 Identities = 69/232 (29%), Positives = 100/232 (43%), Gaps = 14/232 (6%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I P P TL CRA G PSP I W K G L+ L + G F+ + Sbjct: 781 PTIQHGPQVFNTIEGTPVTLPCRAIGVPSPEITWTKEGKLLYLGGPDFFLDSDGSLFINS 840 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE------FRLEPESKQSAQGDTV 125 G +++G + C ATN+ G A SR L V V EP +G+ Sbjct: 841 PSG---NESGEFICMATNAAGHA-SRRVQLTVYVRPRSNAEGPGSSAEPLRMSVTEGEDA 896 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 +L C P P + W K + L+ R H + ++ I +++ +D+G Y C+A N Sbjct: 897 ILPC-EVHSVPPPTITWAK--ERLISPFAPRHHPLPSCSMKILESKVSDSGIYVCVASNI 953 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 AG ++ L + + P + GP + Q G V C V G P P + W R Sbjct: 954 AGNLTLSVL-LSVLVPPSIQPGPRVMKVQVGHPVELPCMVSGVPEPTLTWTR 1004 Score = 89.4 bits (212), Expect = 5e-16 Identities = 69/232 (29%), Positives = 102/232 (43%), Gaps = 18/232 (7%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLD 260 P I+ +V A GS C V ++ W R GG + LG +V VLD+ SL+L Sbjct: 376 PPAISVKGNVTASPGSRAVLTCHVISTVSFNLTWLR--GGRDARLGPQVNVLDNRSLQLS 433 Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320 +V G Y C A N G S YLTV + P +++ P + G+ C+A+G P Sbjct: 434 SVSPDQSGWYECVAMNEGGVTSEQIYLTVQEEPRVSVHPANQTFSRGDEVHMRCSASGYP 493 Query: 321 EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGS 380 P + W+ + + SR + DG +L I +T++ D C A N AG+ Sbjct: 494 VPRLVWT---HNDMFVKASSRHRMGP----DG--MLAIRNTEQKDG-GVYRCLASNQAGT 543 Query: 381 SFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432 LT P++T + + + AV C A TP+P I WY Sbjct: 544 DATNSVLTYIES-----PVVTVALGDVLVALGEAAVLACAASGTPQPEIWWY 590 Score = 79.0 bits (186), Expect = 7e-13 Identities = 63/218 (28%), Positives = 97/218 (44%), Gaps = 12/218 (5%) Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77 P + V L C AGG P P++ W K GV V +L GG + + Sbjct: 1394 PTERKVVLSASLILECEAGGRPPPSLTWLKDGVPVRHSQSLRVLELGGKIEISSA---TL 1450 Query: 78 SDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136 SD+G Y C AT+ G + + T+ V + + S + +EC G+P Sbjct: 1451 SDSGRYVCVATSVAGEKEVKYDVTVLVPPFIQGAGVITHSTVII-NHPLEMEC-QATGTP 1508 Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196 P V W K+G+ + G+ G L++ A+ +D R+QC+A N AG + T+ Sbjct: 1509 TPVVTWYKDGKPIQ-QGEGWRVAAGGQRLLVSRAQISDTARFQCVAANEAGDIQRDF-TV 1566 Query: 197 KIHIKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLP 231 +H +P + DV+ QT G S +C+ G PLP Sbjct: 1567 VVH-EPPSVPHAGDVINQTILAGFSTQLECKATGTPLP 1603 Score = 77.4 bits (182), Expect = 2e-12 Identities = 59/235 (25%), Positives = 98/235 (41%), Gaps = 12/235 (5%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 ++S E P I +VT + A L C + S + W +GG ++L Sbjct: 370 ISSSEPPPAISVKGNVTASPGSRAVLTCHVISTVSFNLTWLRGGRDARLGPQVNVLDNRS 429 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDT 124 L + + +G Y C A N G + +++ V E + P ++ ++GD Sbjct: 430 LQLSSVSPDQ----SGWYECVAMNEGGVTSEQ---IYLTVQEEPRVSVHPANQTFSRGDE 482 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 V + C G P P + W N + SR + G L I++ Q D G Y+C+A N Sbjct: 483 VHMRC-SASGYPVPRLVWTHND--MFVKASSRHRMGPDGMLAIRNTEQKDGGVYRCLASN 539 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239 AGT ++ + L P + DV+ G + C G P P++ W ++A Sbjct: 540 QAGT-DATNSVLTYIESPVVTVALGDVLVALGEAAVLACAASGTPQPEIWWYKAA 593 Score = 73.7 bits (173), Expect = 3e-11 Identities = 84/306 (27%), Positives = 118/306 (38%), Gaps = 24/306 (7%) Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235 G +A A+GT + I K P P D + GS+VT C V G P P V W Sbjct: 570 GEAAVLACAASGTPQPEIWWYKA--APEFTREPSDTASDIGSNVTLWCLVRGYPDPQVTW 627 Query: 236 RRSAG--GGNMPLGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD- 291 RR G N P V L ++ + DE Y CEA N G + A +TV Sbjct: 628 RRQDGLPPFNRPRTYGSVTQSRRGLHFTHLWVEDEAVYVCEAHNHFGKIEAKARITVTGL 687 Query: 292 -PPSINLSPNSVNVESGNVARFTCT-ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349 P I SP+ ++V C G P P W N ++ + D+Y Sbjct: 688 VLPVIARSPSVLSVVEDQPVTLPCVLLAGNPLPARQWL--HNYGLV----TTDQY-VKVR 740 Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409 DG + + + D C A N G L V P I +GP Sbjct: 741 KDGSLHI---ERVRLDHVGDYTCLAENVVGLYNHTTTLNV-----YVIPTIQHGPQVFNT 792 Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468 + PC AI P P I W EG+ L + + +DG+L + ++SG + C+ Sbjct: 793 IEGTPVTLPCRAIGVPSPEITWTKEGKLLYLGGPDFFLDSDGSLFINSPSGNESGEFICM 852 Query: 469 ASSRHG 474 A++ G Sbjct: 853 ATNAAG 858 Score = 56.4 bits (130), Expect = 4e-06 Identities = 37/140 (26%), Positives = 60/140 (42%), Gaps = 7/140 (5%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64 Y+T E P + P + T +R + C A G P P + W + V + + + P Sbjct: 459 YLTVQEEPRVSVHPANQTFSRGDEVHMRCSASGYPVPRLVWTHNDMFVKASSRHRMGP-D 517 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124 G+ +R T D GVY C A+N GT + + ++ + A G+ Sbjct: 518 GMLAIRNTE---QKDGGVYRCLASNQAGTDATNSVLTYIE--SPVVTVALGDVLVALGEA 572 Query: 125 VVLECLPPRGSPEPNVYWKK 144 VL C G+P+P ++W K Sbjct: 573 AVLAC-AASGTPQPEIWWYK 591 Score = 50.0 bits (114), Expect = 4e-04 Identities = 47/198 (23%), Positives = 83/198 (41%), Gaps = 17/198 (8%) Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 PP+I++ N V G+ A TC + W G + P ++ V D Sbjct: 376 PPAISVKGN-VTASPGSRAVLTCHVISTVSFNLTWLRGGRDARLGPQVN--------VLD 426 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411 + L ++ + S C A+N G + + LTV + P ++ P+NQT Sbjct: 427 NRS-LQLSSVSPDQS-GWYECVAMNEGGVTSEQIYLTVQEE-----PRVSVHPANQTFSR 479 Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471 C+A P P + W + + R + DG L +++ ++ D G Y C+AS+ Sbjct: 480 GDEVHMRCSASGYPVPRLVWTHNDMFVKASSRHRMGPDGMLAIRNTEQKDGGVYRCLASN 539 Query: 472 RHGKYVWSGAL-LVDSPI 488 + G + L ++SP+ Sbjct: 540 QAGTDATNSVLTYIESPV 557 Score = 49.2 bits (112), Expect = 7e-04 Identities = 55/201 (27%), Positives = 80/201 (39%), Gaps = 36/201 (17%) Query: 22 TVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAG 81 TV + P + C+A G+P+P + WYK G + + AGG L + ++ SD Sbjct: 1491 TVIINHPLEMECQATGTPTPVVTWYKDGKPIQQGEGWRVA-AGGQRLL-VSRAQI-SDTA 1547 Query: 82 VYWCEATNSYGTA-RSRNATLHVA--------VLREE----FRLEPESKQ---------- 118 + C A N G R +H V+ + F + E K Sbjct: 1548 RFQCVAANEAGDIQRDFTVVVHEPPSVPHAGDVINQTILAGFSTQLECKATGTPLPVPPV 1607 Query: 119 -SAQGDTVV--------LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169 S+QG TV LEC G P P+ W K+G + L +G L + Sbjct: 1608 ISSQGGTVTVLVNEPARLEC-EATGVPSPSFTWLKDGSPVASVPHGLQVLSEGRALSLNS 1666 Query: 170 ARQTDAGRYQCIARNAAGTRE 190 A TD G Y C+A NA G ++ Sbjct: 1667 ALVTDTGTYTCVAVNAGGEQQ 1687 Score = 49.2 bits (112), Expect = 7e-04 Identities = 31/82 (37%), Positives = 39/82 (47%), Gaps = 4/82 (4%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTH-RSILPAGGLFFLR 70 P I Q VTV ++PA L C A G PSP+ W K G V S H +L G L Sbjct: 1606 PVISSQGGTVTVLVNEPARLECEATGVPSPSFTWLKDGSPVASVPHGLQVLSEGRALSLN 1665 Query: 71 ATHGRVHSDAGVYWCEATNSYG 92 + + +D G Y C A N+ G Sbjct: 1666 SA---LVTDTGTYTCVAVNAGG 1684 Score = 47.2 bits (107), Expect = 0.003 Identities = 34/106 (32%), Positives = 48/106 (45%), Gaps = 6/106 (5%) Query: 388 TVTSDDDRPPPI-ITNGPSNQTLPIK---SMAVFPCTAICTPEPIIAWYFEGEALIQNHR 443 T+T D PP + + P N L + FPC A P+P+I W G+ L N Sbjct: 999 TLTWTRDVPPVVEVLEPPFNSPLQERVANQRIAFPCPAKGLPKPVIRWLRNGQELTGNEP 1058 Query: 444 R-NVTNDGTLVL-KDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 ++ DGTL+L + DSG Y C A++ G L V+ P Sbjct: 1059 GVSILEDGTLLLLASVSPLDSGEYVCAAANDAGSTERKYQLKVNVP 1104 Score = 38.7 bits (86), Expect = 0.96 Identities = 31/107 (28%), Positives = 44/107 (41%), Gaps = 5/107 (4%) Query: 368 NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427 +++ S++ AG V G S + PP I G N T S AV C I T Sbjct: 351 SSVSFSSIKPAG---VEGDWEKISSSEPPPAISVKG--NVTASPGSRAVLTCHVISTVSF 405 Query: 428 IIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 + W G + NV ++ +L L + SG Y CVA + G Sbjct: 406 NLTWLRGGRDARLGPQVNVLDNRSLQLSSVSPDQSGWYECVAMNEGG 452 Score = 37.9 bits (84), Expect = 1.7 Identities = 24/93 (25%), Positives = 41/93 (44%), Gaps = 3/93 (3%) Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDG-SL 257 + P + + V +C G P P W + ++P G ++VL +G +L Sbjct: 1604 VPPVISSQGGTVTVLVNEPARLECEATGVPSPSFTWLKDGSPVASVPHG-LQVLSEGRAL 1662 Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290 L++ ++ D G Y+C A N+ G L VY Sbjct: 1663 SLNSALVTDTGTYTCVAVNAGGEQQREYDLRVY 1695 Score = 36.7 bits (81), Expect = 3.9 Identities = 18/46 (39%), Positives = 25/46 (54%) Query: 2 SDDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK 47 ++ +T E+P + DV VA + A L C A G+P P I WYK Sbjct: 546 TNSVLTYIESPVVTVALGDVLVALGEAAVLACAASGTPQPEIWWYK 591 >UniRef50_A7SM31 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 194 Score = 151 bits (366), Expect = 1e-34 Identities = 82/191 (42%), Positives = 111/191 (58%), Gaps = 7/191 (3%) Query: 106 LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNL 165 LR +FR EP+ G+ +L+C PP+G P P V W KN + + DG R+ V GNL Sbjct: 1 LRSKFRAEPKDLSITIGNRAILKCNPPKGRPAPTVTWLKNTKAYVPDG-VRIQKVSPGNL 59 Query: 166 VIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV 225 VI A++ D G YQC+A NA G R+S +AT+ I KP +I P+DVV G++ F C+ Sbjct: 60 VISIAQKADMGTYQCVAANAVGRRKSRVATVTIKAKPEIIQRPKDVVIVEGNTALFTCKA 119 Query: 226 GGDPLPDVLWRRSAGGGNM-PL---GRVKVLDDGSLRLDNVILADEGEYSCEAEN--SVG 279 G PLP V W + + G M P+ GR V +G LR+ +V DEGEY C A + +G Sbjct: 120 TGSPLPTVFWEKKSKGQPMFPMQDYGRFFVSSNGELRISSVKKEDEGEYVCSALSPAGLG 179 Query: 280 AVSASGYLTVY 290 A SA LTV+ Sbjct: 180 ASSARAMLTVW 190 Score = 81.8 bits (193), Expect = 1e-13 Identities = 61/187 (32%), Positives = 89/187 (47%), Gaps = 11/187 (5%) Query: 208 PEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNVILA 265 P+D+ G+ +C G P P V W ++ +P G R++ + G+L + A Sbjct: 9 PKDLSITIGNRAILKCNPPKGRPAPTVTWLKNTKA-YVPDGVRIQKVSPGNLVISIAQKA 67 Query: 266 DEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTM 324 D G Y C A N+VG S +T+ P I P V + GN A FTC ATG P PT+ Sbjct: 68 DMGTYQCVAANAVGRRKSRVATVTIKAKPEIIQRPKDVVIVEGNTALFTCKATGSPLPTV 127 Query: 325 FWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA--GSSF 382 FW + +FP ++ ++ +G L I+ K D VCSA++ A G+S Sbjct: 128 FWEKKSKGQPMFPMQDYGRFFVSS--NG--ELRISSVKKED-EGEYVCSALSPAGLGASS 182 Query: 383 VRGKLTV 389 R LTV Sbjct: 183 ARAMLTV 189 Score = 71.7 bits (168), Expect = 1e-10 Identities = 52/180 (28%), Positives = 78/180 (43%), Gaps = 9/180 (5%) Query: 17 QPLDVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75 +P D+++ A L C G P+P + W K V D R + G + Sbjct: 8 EPKDLSITIGNRAILKCNPPKGRPAPTVTWLKNTKAYVPDGVRIQKVSPGNLVISIAQ-- 65 Query: 76 VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGS 135 +D G Y C A N+ G +SR AT+ + + E P+ +G+T + C GS Sbjct: 66 -KADMGTYQCVAANAVGRRKSRVATVTIKA-KPEIIQRPKDVVIVEGNTALFTC-KATGS 122 Query: 136 PEPNVYWKK--NGQTLLFDGD-SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192 P P V+W+K GQ + D R + G L I ++ D G Y C A + AG S+ Sbjct: 123 PLPTVFWEKKSKGQPMFPMQDYGRFFVSSNGELRISSVKKEDEGEYVCSALSPAGLGASS 182 Score = 51.2 bits (117), Expect = 2e-04 Identities = 51/182 (28%), Positives = 81/182 (44%), Gaps = 19/182 (10%) Query: 299 PNSVNVESGNVARFTCTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 P +++ GN A C GRP PT+ W ++ + + G+ K V G V++ Sbjct: 9 PKDLSITIGNRAILKCNPPKGRPAPTVTW-LKNTKAYVPDGVRIQK-----VSPGNLVIS 62 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417 I K D T C A N G R K V + + P I P + + + A+F Sbjct: 63 I--AQKADM-GTYQCVAANAVG----RRKSRVATVTIKAKPEIIQRPKDVVIVEGNTALF 115 Query: 418 PCTAICTPEPIIAWY--FEGEAL--IQNHRRN-VTNDGTLVLKDLDKSDSGTYTCVASSR 472 C A +P P + W +G+ + +Q++ R V+++G L + + K D G Y C A S Sbjct: 116 TCKATGSPLPTVFWEKKSKGQPMFPMQDYGRFFVSSNGELRISSVKKEDEGEYVCSALSP 175 Query: 473 HG 474 G Sbjct: 176 AG 177 Score = 40.3 bits (90), Expect = 0.31 Identities = 31/103 (30%), Positives = 43/103 (41%), Gaps = 8/103 (7%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG----VLVVSDTHRSIL 61 VT P II++P DV + A C+A GSP P + W K + + D R + Sbjct: 90 VTIKAKPEIIQRPKDVVIVEGNTALFTCKATGSPLPTVFWEKKSKGQPMFPMQDYGRFFV 149 Query: 62 PAGGLFFLRATHGRVHSDAGVYWCEATNSYGT-ARSRNATLHV 103 + G + + D G Y C A + G A S A L V Sbjct: 150 SSNGELRISSVK---KEDEGEYVCSALSPAGLGASSARAMLTV 189 Score = 38.3 bits (85), Expect = 1.3 Identities = 35/129 (27%), Positives = 56/129 (43%), Gaps = 6/129 (4%) Query: 404 PSNQTLPIKSMAVFPCTAIC-TPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKDLDKSD 461 P + ++ I + A+ C P P + W +A + + R + G LV+ K+D Sbjct: 9 PKDLSITIGNRAILKCNPPKGRPAPTVTWLKNTKAYVPDGVRIQKVSPGNLVISIAQKAD 68 Query: 462 SGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSV- 520 GTY CVA++ G+ S V P I R DV + G T T T + + Sbjct: 69 MGTYQCVAANAVGRRK-SRVATVTIKAKPEI-IQRPKDVVIVEG-NTALFTCKATGSPLP 125 Query: 521 TLSWSQNNK 529 T+ W + +K Sbjct: 126 TVFWEKKSK 134 >UniRef50_UPI000155CDCD Cluster: PREDICTED: similar to adlican; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to adlican - Ornithorhynchus anatinus Length = 2908 Score = 151 bits (365), Expect = 1e-34 Identities = 144/500 (28%), Positives = 214/500 (42%), Gaps = 50/500 (10%) Query: 9 GEAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYK--GGVLVVSDT--HRSILPA 63 GE P I+ + +++ A L C A G P P + W + G L+ +T HR + Sbjct: 1941 GEKPRIVTKSAPTLSIPAETDAVLPCEATGEPRPFVTWTRIATGALMTPNTKTHRFEVLR 2000 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-G 122 G F +R + D G Y C ATN +G + A L VA E + G Sbjct: 2001 NGTFVIRNAQPQ---DGGRYLCTATNLHGLDKMAVA-LSVAARPPEMATAHYRDVTVYLG 2056 Query: 123 DTVVLECLPPRGSPEPNVYW----KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY 178 DT+ +ECL G P P++ W +K QT+ ++R+ L L I+DA +D G Y Sbjct: 2057 DTIAMECLAD-GVPPPHISWIFPDRKVWQTVS-TAEARITLHRNRTLSIKDATFSDRGVY 2114 Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 +C+A NAAGT +S L + P +I E++ G V C P P + WR Sbjct: 2115 KCVAGNAAGT-DSLAVRLHVAALPPIIQQEKRENISLPPGIGVNIHCSAKAAPPPTIRWR 2173 Query: 237 RSAGGGNMPL----GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV--- 289 G P G V V +G+L L +V D G Y C A N+VG + LTV Sbjct: 2174 LLDGTQIRPSQFANGNVFVFPNGTLYLRHVAPEDSGTYECVAANAVGVARRTVRLTVRQG 2233 Query: 290 -YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI--IFPGMSRDKYHA 346 + SP +V G R C+A+G P PT+ W + R I +F +R + A Sbjct: 2234 GAEARIARTSPRQTDVTYGGTLRLDCSASGDPRPTILWRLPSKRMIDSLFSLETRTRVLA 2293 Query: 347 TAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN 406 + V ++ D D D +C A N G ++ VT RP I + Sbjct: 2294 NG---SLVVQSVTDGDAGD----YLCVARNRLGDDSAALRVNVTM---RPARIERREEPD 2343 Query: 407 QTLPIKSMAVFPCTAICTPEPIIAWYF-EG---EALIQN-------HRRNVTNDGTLVLK 455 + + C A P P ++W +G AL+Q+ R + ++GTL Sbjct: 2344 RRVAYGGALTVDCVASGLPVPDVSWSLPDGSTVNALMQSDDGGGGAKRYVLFHNGTLYFH 2403 Query: 456 DLDKSDSGTYTCVASSRHGK 475 D+ + G YTC+A + G+ Sbjct: 2404 DVGLGEQGDYTCLAENPMGR 2423 Score = 135 bits (327), Expect = 6e-30 Identities = 140/481 (29%), Positives = 207/481 (43%), Gaps = 57/481 (11%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF-FLRATHGRVH---SDAGVYWCE 86 ++C A +P P IRW +L + S G +F F T H D+G Y C Sbjct: 2158 IHCSAKAAPPPTIRWR---LLDGTQIRPSQFANGNVFVFPNGTLYLRHVAPEDSGTYECV 2214 Query: 87 ATNSYGTARSRNATLHVAVLREEFRL---EPESKQSAQGDTVVLECLPPRGSPEPNVYWK 143 A N+ G AR R L V E R+ P G T+ L+C G P P + W+ Sbjct: 2215 AANAVGVAR-RTVRLTVRQGGAEARIARTSPRQTDVTYGGTLRLDC-SASGDPRPTILWR 2272 Query: 144 KNGQTL---LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200 + + LF ++R ++ G+LV+Q DAG Y C+ARN G +SA + + + Sbjct: 2273 LPSKRMIDSLFSLETRTRVLANGSLVVQSVTDGDAGDYLCVARNRLGD-DSAALRVNVTM 2331 Query: 201 KPYLITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG----------GNMPLGR 248 +P I E D G ++T C G P+PDV W G G R Sbjct: 2332 RPARIERREEPDRRVAYGGALTVDCVASGLPVPDVSWSLPDGSTVNALMQSDDGGGGAKR 2391 Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-DPPSINLSPNSV-NVES 306 + +G+L +V L ++G+Y+C AEN +G + V +P +I +SV +V Sbjct: 2392 YVLFHNGTLYFHDVGLGEQGDYTCLAENPMGRDEMRIRVRVLAEPAAIRNKGDSVADVLY 2451 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 G C + G P PT+ W N I P S KY + DG L I + ++D Sbjct: 2452 GEAVSVACESRGEPAPTVTWLSPANLPI--PPASA-KYRVSR--DG--TLLIREARRSDG 2504 Query: 367 RNTIVCSAVNYAGS--SFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA------VFP 418 N C N AG VR +++V R P I NG + ++ +A + Sbjct: 2505 GN-YTCVVRNGAGEDRKVVRVRVSV-----RRPRI--NGSPDAVTTVREIAARGDRKLID 2556 Query: 419 CTAICTPEPIIAWYF-EGEAL---IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 C A P P + W F +G L R V +GTL ++DL +SDS C+ + G Sbjct: 2557 CRAEGVPAPRVLWAFPQGVVLPAPYYGRRITVHRNGTLDVRDLRESDSVRLVCIGRNEGG 2616 Query: 475 K 475 + Sbjct: 2617 E 2617 Score = 116 bits (278), Expect = 5e-24 Identities = 140/537 (26%), Positives = 214/537 (39%), Gaps = 56/537 (10%) Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG----LFFLRA 71 E+P D VA T++C A G P P + W V+ +S GG + F Sbjct: 2340 EEP-DRRVAYGGALTVDCVASGLPVPDVSWSLPDGSTVNALMQSDDGGGGAKRYVLFHNG 2398 Query: 72 T---HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GDTV 125 T H + G Y C A N G R + V VL E + + A G+ V Sbjct: 2399 TLYFHDVGLGEQGDYTCLAENPMGRDEMR---IRVRVLAEPAAIRNKGDSVADVLYGEAV 2455 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 + C RG P P V W + ++ + G L+I++AR++D G Y C+ RN Sbjct: 2456 SVAC-ESRGEPAPTVTWLSPANLPIPPASAKYRVSRDGTLLIREARRSDGGNYTCVVRNG 2514 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVV------AQTGSSVTFQCRVGGDPLPDVLWRRSA 239 AG + + +++ ++ I G D V A G CR G P P VLW Sbjct: 2515 AG-EDRKVVRVRVSVRRPRINGSPDAVTTVREIAARGDRKLIDCRAEGVPAPRVLW-AFP 2572 Query: 240 GGGNMPL----GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295 G +P R+ V +G+L + ++ +D C N G LTV DP Sbjct: 2573 QGVVLPAPYYGRRITVHRNGTLDVRDLRESDSVRLVCIGRNEGGEARLVVQLTVLDPRGG 2632 Query: 296 NLSPNSVNVE----SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 + + V+ E +G+ C+A GRP+PT+ W + + PG R Sbjct: 2633 PVFRDPVDEEITAAAGHTINLNCSAEGRPDPTVLWILPDGSEV--PGGRR---LGRFFHK 2687 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411 G VL I+ D+ C A N AGS+ R L V RP + P +TL Sbjct: 2688 GDGVLHISALAPADA-GPYRCLARNPAGSAQRRVSLGVGPGPARPVSV----PGGETL-- 2740 Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQN----HRRNVTNDGTLVLKDLDKSDSGTYTC 467 + C + ++W G ++ R + +G+L +++ D GTY C Sbjct: 2741 ----LLHCGPPGSRPVGVSWTLPGGRVLDRPQTAGRFTLFENGSLSVREASGEDRGTYLC 2796 Query: 468 -VASSRHGKYVWSGALLVDSPINPNIHFFRAADV----SSLPGPPTKPITHNVTDTS 519 A+ HG + S + V +P P + RA ++ G P +T + D S Sbjct: 2797 RAAAVDHGPPLTSVPVAVVAPTAPRVVRSRAGSSVRLDCAVAGVPGAEVTWRLPDGS 2853 Score = 85.4 bits (202), Expect = 8e-15 Identities = 91/295 (30%), Positives = 129/295 (43%), Gaps = 40/295 (13%) Query: 14 IIEQPLD--VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG---GLFF 68 + P+D +T A LNC A G P P + W ++ D S +P G G FF Sbjct: 2634 VFRDPVDEEITAAAGHTINLNCSAEGRPDPTVLW------ILPDG--SEVPGGRRLGRFF 2685 Query: 69 LRATHGRVH------SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122 + G +H +DAG Y C A N G+A+ R +L V P S G Sbjct: 2686 HKGD-GVLHISALAPADAGPYRCLARNPAGSAQ-RRVSLGVG----PGPARPVSVPG--G 2737 Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS--RMHLVDGGNLVIQDARQTDAGRYQC 180 +T++L C PP GS V W G +L + R L + G+L +++A D G Y C Sbjct: 2738 ETLLLHCGPP-GSRPVGVSWTLPGGRVLDRPQTAGRFTLFENGSLSVREASGEDRGTYLC 2796 Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 R AA + ++ + + T P V ++ GSSV C V G P +V WR G Sbjct: 2797 --RAAAVDHGPPLTSVPVAV--VAPTAPRVVRSRAGSSVRLDCAVAGVPGAEVTWRLPDG 2852 Query: 241 -----GGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 G L K+L G+L + D G YSC A N +G+ S + Y+ V Sbjct: 2853 SPLTAGPRARLYGNKLLHPQGALLIQRATPGDAGFYSCTARNQLGSHSQTTYVHV 2907 Score = 46.0 bits (104), Expect = 0.006 Identities = 46/168 (27%), Positives = 70/168 (41%), Gaps = 13/168 (7%) Query: 122 GDTVVLECLPPRGSPEPNVYWK-KNGQTLLF--DG-DSRMHLVDGGNLVIQDARQTDAGR 177 G L C R S P + W +G L DG D R + + G L ++ A D+G Sbjct: 518 GSGFELRC-DARASESPEILWVLPDGSALRAPSDGRDGRFSVREDGRLTLRAAGYPDSGP 576 Query: 178 YQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVA---QTGSSVTFQCRVGGDPLPDVL 234 Y+C+AR T +S + + + P + G +V A + G +T C P + Sbjct: 577 YRCVARVRDET-DSVVHRVSVQ-PPEVRPGDGEVSAIEKRAGEPITLPCGALAIPEAQLS 634 Query: 235 W---RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279 W R R +L++G+L + +AD G Y C A N G Sbjct: 635 WILPSREVVSDFSNSSRGFLLENGTLLIPGGQVADTGYYRCVAVNRQG 682 Score = 40.7 bits (91), Expect = 0.24 Identities = 49/168 (29%), Positives = 70/168 (41%), Gaps = 19/168 (11%) Query: 31 LNCRAGGSPSPAIRWY--KGGVL-VVSDTH--RSILPAGGLFFLRATHGRVHSDAGVYWC 85 L C A S SP I W G L SD R + G LRA + D+G Y C Sbjct: 523 LRCDARASESPEILWVLPDGSALRAPSDGRDGRFSVREDGRLTLRAAG---YPDSGPYRC 579 Query: 86 EATNSYGTARSRNATLH-VAVLREEFRL---EPESKQSAQGDTVVLECLPPRGSPEPNVY 141 A T ++ +H V+V E R E + + G+ + L C PE + Sbjct: 580 VARVRDET----DSVVHRVSVQPPEVRPGDGEVSAIEKRAGEPITLPC-GALAIPEAQLS 634 Query: 142 WKKNGQTLL--FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 W + ++ F SR L++ G L+I + D G Y+C+A N G Sbjct: 635 WILPSREVVSDFSNSSRGFLLENGTLLIPGGQVADTGYYRCVAVNRQG 682 Score = 36.7 bits (81), Expect = 3.9 Identities = 17/61 (27%), Positives = 31/61 (50%), Gaps = 4/61 (6%) Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRN----VTNDGTLVLKDLDKSDSGTYTCVASSRH 473 PC A+ PE ++W ++ + + + +GTL++ +D+G Y CVA +R Sbjct: 622 PCGALAIPEAQLSWILPSREVVSDFSNSSRGFLLENGTLLIPGGQVADTGYYRCVAVNRQ 681 Query: 474 G 474 G Sbjct: 682 G 682 Score = 35.9 bits (79), Expect = 6.7 Identities = 34/138 (24%), Positives = 48/138 (34%), Gaps = 11/138 (7%) Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG-NMPL----GRVKVLDDGSLRL 259 + G V+A GS +C P++LW G P GR V +DG L L Sbjct: 509 VDGARTVLA--GSGFELRCDARASESPEILWVLPDGSALRAPSDGRDGRFSVREDGRLTL 566 Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV---ESGNVARFTCTA 316 D G Y C A S ++V PP + V+ +G C A Sbjct: 567 RAAGYPDSGPYRCVARVRDETDSVVHRVSV-QPPEVRPGDGEVSAIEKRAGEPITLPCGA 625 Query: 317 TGRPEPTMFWSVEGNRTI 334 PE + W + + Sbjct: 626 LAIPEAQLSWILPSREVV 643 >UniRef50_Q0E8G9 Cluster: CG33274-PB; n=9; Endopterygota|Rep: CG33274-PB - Drosophila melanogaster (Fruit fly) Length = 1876 Score = 149 bits (362), Expect = 3e-34 Identities = 175/779 (22%), Positives = 311/779 (39%), Gaps = 57/779 (7%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 PYI E P +T + C G P I W + G + + + G L + Sbjct: 382 PYIREMP-KITGISGSDLIVKCPVAGYPIDKIHWERDGQTLPINRRQRAYNNGTLIIEQL 440 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131 DAG Y C A N RN + V V + ++ + +G + C Sbjct: 441 QR---LEDAGTYTCMAQNKQKQTSRRNVEIQVLVPPKIMPIQAMTNMLREGMRAAISCQI 497 Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVD--GGNLVIQDARQTDAGRYQCIARNAAGTR 189 G + W++NG+ L+ G+ +D +LVI+ +G Y CIA N AGT Sbjct: 498 LEGDLPVSFRWERNGKPLIGTGNEVFRRLDEYSASLVIEHISSDHSGNYTCIASNVAGTE 557 Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GN---- 243 + L +++ P I P+D AQ G+ V C+ G P P + W+++ G G Sbjct: 558 RFTVP-LTVNVPPKWILEPKDSSAQAGADVLLHCQSSGYPTPTITWKKAIGPTPGEYKDF 616 Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSV 302 + V++ +G++ + +G + CEA+N++G+ VS +L V P + Sbjct: 617 LYEPTVQLFPNGTIFFKKISKESQGHFLCEAKNNIGSGVSKVIFLKVNVPAHFQTKTKQI 676 Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGM-SRDKYHATAVFDG-VTVLTIND 360 +V G C G W ++ + + + SR + DG V+ L I+ Sbjct: 677 SVAKGKQVHVQCNVQGDNPIDFKWKIQATQQYLDESLDSRYTIRDQVLDDGMVSELGISH 736 Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420 T + D+ +C A N G + +L V ++P + N +++L + F Sbjct: 737 TYRQDT-GIYICQASNAFGQDEMSIQLIVQEVPEQPKNLRINSQQSRSLQLTWSQPF--- 792 Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480 A +P Y++ + I + ++T G + ++ + + S K G Sbjct: 793 AGNSPIEEYHIYYKQISDIWQNAEHLTIAGAQTVINIQQLRPAKAYHIRMSAENKL---G 849 Query: 481 ALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSIL-GYQ 539 A S + + +V S GPP + T + ++W + + IL GY Sbjct: 850 A----SEFSEVVQVTTLEEVPS--GPPLAVRAEPKSSTEIFVTWDAPERDHWNGILLGYY 903 Query: 540 VEVFSRETLSGNNT-PRNSRGWVVIARRVHQTHYVVKSLIPGIT-YMFIVRTENSHGLSG 597 V T P + + R H V + + T Y IV+ S G SG Sbjct: 904 VGYQMSLTPEDKEVNPTQGFSFKTVEVRSHFGGETVLANLNKFTQYHVIVQAYTSQG-SG 962 Query: 598 PSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATP-IDSKTIKLMWEIL 656 P +V +D S S + ++L + + + P ID + K+ Sbjct: 963 PPSKEIAVQTMEDVPS-------SPPESPQCDVLGSTSIYITWSPPDIDGQNGKI----- 1010 Query: 657 NFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEG 716 +G +++ +D + E + + + +N E +LRKYT Y +++ + K +G Sbjct: 1011 -----KGYKVFYISVDEL-YETDPEVVKSTNQYVTIE--NLRKYTNYTVWVLAYTKVGDG 1062 Query: 717 KPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLD 775 + +T +DVP P I+ +++ + + W PP+ L NG ITGY ++ L+ Sbjct: 1063 MKTKPFYCRTHEDVPSAPQA-IKAIPASSSKIIISWLPPD--LPNGDITGYTFYMSMLE 1118 Score = 118 bits (285), Expect = 7e-25 Identities = 124/475 (26%), Positives = 194/475 (40%), Gaps = 39/475 (8%) Query: 30 TLNCRAGGSPSPAIRWYK---GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86 TL C A G P P RW+K +L + + R + + GL L+ T R+ D+G Y C Sbjct: 116 TLPCIAQGHPVPTYRWFKEENEQLLPLQLSERITIVSAGL--LKITKARL-EDSGKYLCW 172 Query: 87 ATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146 N+ G + + A L L+P+ + +C+ G P +V W +G Sbjct: 173 VNNTAGEETIQVSLTVTAPLTA--HLQPQVQTVDVDKDAQFQCI-VSGHPVHDVNWLHDG 229 Query: 147 QTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT 206 + +L D + L D L+I+ ++ D G YQC N +S P L+ Sbjct: 230 KPILRDNRVEI-LTDPPRLIIKKVQKEDPGMYQCFVSNEWEQIQSTAELQLGDASPELLY 288 Query: 207 GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP------LGR-VKVLDD--GSL 257 + Q G +V+ +C G+PLP W S G +P +G+ V + DD + Sbjct: 289 WFSEQTLQPGPTVSLKCVATGNPLPQFTW--SLDGFPIPDSSRFLVGQYVTIHDDVISHV 346 Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317 + NV D GEY+C A+N++G VS S + +Y P I P + SG+ C Sbjct: 347 NISNVKEEDGGEYTCTAQNAIGKVSHSAKVNIYGLPYIREMPKITGI-SGSDLIVKCPVA 405 Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377 G P + W +G +T+ R + T L I + + T C A N Sbjct: 406 GYPIDKIHWERDG-QTLPINRRQRAYNNGT--------LIIEQLQRLEDAGTYTCMAQNK 456 Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGE 436 + + V PP I+ L A C + P+ W G+ Sbjct: 457 QKQT---SRRNVEIQVLVPPKIMPIQAMTNMLREGMRAAISCQILEGDLPVSFRWERNGK 513 Query: 437 ALI----QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 LI + RR +LV++ + SG YTC+AS+ G ++ L V+ P Sbjct: 514 PLIGTGNEVFRRLDEYSASLVIEHISSDHSGNYTCIASNVAGTERFTVPLTVNVP 568 Score = 117 bits (281), Expect = 2e-24 Identities = 129/488 (26%), Positives = 204/488 (41%), Gaps = 38/488 (7%) Query: 127 LECLPPRGSPEPNVYWKK--NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 L C+ +G P P W K N Q L R+ +V G L I AR D+G+Y C N Sbjct: 117 LPCIA-QGHPVPTYRWFKEENEQLLPLQLSERITIVSAGLLKITKARLEDSGKYLCWVNN 175 Query: 185 AAGTRESAI-----ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239 AG + A L H++P + T D AQ FQC V G P+ DV W Sbjct: 176 TAGEETIQVSLTVTAPLTAHLQPQVQTVDVDKDAQ------FQCIVSGHPVHDVNWLHD- 228 Query: 240 GGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP-PSINL 297 G + RV++L D L + V D G Y C N + ++ L + D P + Sbjct: 229 GKPILRDNRVEILTDPPRLIIKKVQKEDPGMYQCFVSNEWEQIQSTAELQLGDASPELLY 288 Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY--HATAVFDGVTV 355 + ++ G C ATG P P WS++G P SR + T D ++ Sbjct: 289 WFSEQTLQPGPTVSLKCVATGNPLPQFTWSLDG---FPIPDSSRFLVGQYVTIHDDVISH 345 Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTS-DDDRPPPIITNGPSNQTLPIKSM 414 + I++ + D C+A N G K+ + R P IT G S L +K Sbjct: 346 VNISNVKEEDG-GEYTCTAQNAIGKVSHSAKVNIYGLPYIREMPKIT-GISGSDLIVK-- 401 Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDK-SDSGTYTCVASSRH 473 C P I W +G+ L N R+ N+GTL+++ L + D+GTYTC+A ++ Sbjct: 402 ----CPVAGYPIDKIHWERDGQTLPINRRQRAYNNGTLIIEQLQRLEDAGTYTCMAQNKQ 457 Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVT--DTSVTLSWSQNNK-- 529 K + + + P I +A + L I+ + D V+ W +N K Sbjct: 458 -KQTSRRNVEIQVLVPPKIMPIQAM-TNMLREGMRAAISCQILEGDLPVSFRWERNGKPL 515 Query: 530 IGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRT 589 IG+ + + +++ +S + + + +S + IA V T L + +I+ Sbjct: 516 IGTGNEVFRRLDEYSASLVIEHISSDHSGNYTCIASNVAGTERFTVPLTVNVPPKWILEP 575 Query: 590 ENSHGLSG 597 ++S +G Sbjct: 576 KDSSAQAG 583 Score = 97.5 bits (232), Expect = 2e-18 Identities = 116/480 (24%), Positives = 187/480 (38%), Gaps = 40/480 (8%) Query: 17 QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV 76 QP TV + A C G P + W G ++ D IL ++ Sbjct: 197 QPQVQTVDVDKDAQFQCIVSGHPVHDVNWLHDGKPILRDNRVEILTDPPRLIIKKVQ--- 253 Query: 77 HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDTVVLECLPPRGS 135 D G+Y C +N + +S A L + E L S+Q+ Q G TV L+C+ G+ Sbjct: 254 KEDPGMYQCFVSNEWEQIQS-TAELQLGDASPEL-LYWFSEQTLQPGPTVSLKCV-ATGN 310 Query: 136 PEPNVYWKKNG------QTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189 P P W +G L +H ++ I + ++ D G Y C A+NA G + Sbjct: 311 PLPQFTWSLDGFPIPDSSRFLVGQYVTIHDDVISHVNISNVKEEDGGEYTCTAQNAIG-K 369 Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-R 248 S A + I+ PY+ P+ + +GS + +C V G P+ + W R G +P+ R Sbjct: 370 VSHSAKVNIYGLPYIREMPK-ITGISGSDLIVKCPVAGYPIDKIHWERD--GQTLPINRR 426 Query: 249 VKVLDDGSLRLDNV-ILADEGEYSCEAENSVGAVSASGY-LTVYDPPSINLSPNSVN-VE 305 + ++G+L ++ + L D G Y+C A+N S + V PP I N + Sbjct: 427 QRAYNNGTLIIEQLQRLEDAGTYTCMAQNKQKQTSRRNVEIQVLVPPKIMPIQAMTNMLR 486 Query: 306 SGNVARFTCTATGRPEPTMF-WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 G A +C P F W G I G + + D + + + + Sbjct: 487 EGMRAAISCQILEGDLPVSFRWERNGKPLI---GTGNEVFRR---LDEYSASLVIEHISS 540 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424 D C A N AG+ + TV + PP I P + + + + C + Sbjct: 541 DHSGNYTCIASNVAGTE----RFTVPLTVNVPPKWILE-PKDSSAQAGADVLLHCQSSGY 595 Query: 425 PEPIIAWY-------FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477 P P I W E + + + +GT+ K + K G + C A + G V Sbjct: 596 PTPTITWKKAIGPTPGEYKDFLYEPTVQLFPNGTIFFKKISKESQGHFLCEAKNNIGSGV 655 Score = 76.6 bits (180), Expect = 4e-12 Identities = 49/178 (27%), Positives = 83/178 (46%), Gaps = 7/178 (3%) Query: 653 WEILNFYYLEGLFIYFRPLD---NITIEYEMKTILHSNDVSGFEI-TSLRKYTKYEFFLI 708 W + Y G + P D N T + KT+ + G + +L K+T+Y + Sbjct: 895 WNGILLGYYVGYQMSLTPEDKEVNPTQGFSFKTVEVRSHFGGETVLANLNKFTQYHVIVQ 954 Query: 709 PFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYN 768 + + G PS QT++DVP PP + + +L +T++++ WSPP++ QNG I GY Sbjct: 955 AYTSQGSGPPSKEIAVQTMEDVPSSPPESPQCDVLGSTSIYITWSPPDIDGQNGKIKGYK 1014 Query: 769 VVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVY 826 V +D + +T T + NL +Y+V + A T +G G ++ Y Sbjct: 1015 VFYISVDELYETDPEVVKSTNQYVT---IENLRKYTNYTVWVLAYTKVGDGMKTKPFY 1069 Score = 64.1 bits (149), Expect = 2e-08 Identities = 89/384 (23%), Positives = 142/384 (36%), Gaps = 47/384 (12%) Query: 122 GDTVVLECLPPRGSPE---PNVYWKKNGQTLLFDGD--SRMHLVDGGNLVIQDARQTDAG 176 G+T VL+C P E + + G L + D + ++ G L I +A DA Sbjct: 3 GNTAVLKCQVPSYMSEFVLVTAWVQDTGMHLYPNTDIGGKYTVLSNGELYINNAGPNDAY 62 Query: 177 R-YQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT-------------GSSVTFQ 222 + Y C N T E I+T I ++T P+ +V T Sbjct: 63 KSYTCRTVNRL-TGEVQISTYPGRI---IVTEPKGMVQPRINVEKHSMRHVVLNGQTTLP 118 Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLG---RVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279 C G P+P W + +PL R+ ++ G L++ L D G+Y C N+ G Sbjct: 119 CIAQGHPVPTYRWFKEENEQLLPLQLSERITIVSAGLLKITKARLEDSGKYLCWVNNTAG 178 Query: 280 AVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGM 339 + LTV P + +L P V+ A+F C +G P + W +G + Sbjct: 179 EETIQVSLTVTAPLTAHLQPQVQTVDVDKDAQFQCIVSGHPVHDVNWLHDGKPIL----- 233 Query: 340 SRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPI 399 RD + + L I K D C + + + + + T P Sbjct: 234 -RD--NRVEILTDPPRLIIKKVQKEDP-GMYQC----FVSNEWEQIQSTAELQLGDASPE 285 Query: 400 ITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR----RNVTNDGTLV-- 453 + S QTL C A P P W +G + + R + VT ++ Sbjct: 286 LLYWFSEQTLQPGPTVSLKCVATGNPLPQFTWSLDGFPIPDSSRFLVGQYVTIHDDVISH 345 Query: 454 --LKDLDKSDSGTYTCVASSRHGK 475 + ++ + D G YTC A + GK Sbjct: 346 VNISNVKEEDGGEYTCTAQNAIGK 369 Score = 61.3 bits (142), Expect = 2e-07 Identities = 52/217 (23%), Positives = 86/217 (39%), Gaps = 29/217 (13%) Query: 393 DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTL 452 +++ P I + P K PC + P P+ W +G + + R+ + +GTL Sbjct: 1172 NNKVPARIVSFSQRIVTPWKEHLELPCRKVGAPAPVTIWRQDGHNMETSARKTIAKNGTL 1231 Query: 453 VLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPIT 512 +K+ SD+G YTC + GK ++V P P P + Sbjct: 1232 YMKECQASDAGNYTCSVENTWGKDEIVYNIVVKVP----------------PEAPNLTVI 1275 Query: 513 HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHY 572 + TD S+ L W N+ G S ILGY + N R++ W + T + Sbjct: 1276 NAYTD-SLLLEWMDNSH-GGSPILGYVI-----------NYKRDNGDWEELQVDSKTTSH 1322 Query: 573 VVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 ++ +L G Y + N G P + +S T G+ Sbjct: 1323 LLTNLWCGTRYQLYITAYNKIGTGLPCDIVNSYTKGN 1359 Score = 57.6 bits (133), Expect = 2e-06 Identities = 48/190 (25%), Positives = 77/190 (40%), Gaps = 12/190 (6%) Query: 646 SKTIKLMWE--ILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKY 703 S++++L W +E IY++ + +I E TI + V I LR Y Sbjct: 781 SRSLQLTWSQPFAGNSPIEEYHIYYKQISDIWQNAEHLTIAGAQTV--INIQQLRPAKAY 838 Query: 704 EFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGI 763 + K + S TL++VP GPP+ + ++T + + W PE NGI Sbjct: 839 HIRMSAENKLGASEFSEVVQVTTLEEVPSGPPLAVRAEPKSSTEIFVTWDAPERDHWNGI 898 Query: 764 ITGYNVVVNWLDVPANK--------SMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETI 815 + GY V P +K S + H ++ NL Y V + A T Sbjct: 899 LLGYYVGYQMSLTPEDKEVNPTQGFSFKTVEVRSHFGGETVLANLNKFTQYHVIVQAYTS 958 Query: 816 IGLGPFSQKV 825 G GP S+++ Sbjct: 959 QGSGPPSKEI 968 Score = 46.0 bits (104), Expect = 0.006 Identities = 54/204 (26%), Positives = 83/204 (40%), Gaps = 22/204 (10%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG-GVL------VVSDTHR 58 +T P I +P D + L+C++ G P+P I W K G + + Sbjct: 563 LTVNVPPKWILEPKDSSAQAGADVLLHCQSSGYPTPTITWKKAIGPTPGEYKDFLYEPTV 622 Query: 59 SILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ 118 + P G +FF + + G + CEA N+ G+ S+ L V V F+ + + Sbjct: 623 QLFPNGTIFFKKIS----KESQGHFLCEAKNNIGSGVSKVIFLKVNV-PAHFQTKTKQIS 677 Query: 119 SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDG--DSRM----HLVDGG---NLVIQD 169 A+G V ++C +G + WK D DSR ++D G L I Sbjct: 678 VAKGKQVHVQC-NVQGDNPIDFKWKIQATQQYLDESLDSRYTIRDQVLDDGMVSELGISH 736 Query: 170 ARQTDAGRYQCIARNAAGTRESAI 193 + D G Y C A NA G E +I Sbjct: 737 TYRQDTGIYICQASNAFGQDEMSI 760 Score = 39.9 bits (89), Expect = 0.41 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 3/91 (3%) Query: 204 LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNV 262 +++ + +V + CR G P P +WR+ G NM R + +G+L + Sbjct: 1179 IVSFSQRIVTPWKEHLELPCRKVGAPAPVTIWRQD--GHNMETSARKTIAKNGTLYMKEC 1236 Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPP 293 +D G Y+C EN+ G + V PP Sbjct: 1237 QASDAGNYTCSVENTWGKDEIVYNIVVKVPP 1267 Score = 38.7 bits (86), Expect = 0.96 Identities = 16/69 (23%), Positives = 35/69 (50%), Gaps = 3/69 (4%) Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193 G+P P W+++G + + +R + G L +++ + +DAG Y C N G ++ + Sbjct: 1202 GAPAPVTIWRQDGHNM--ETSARKTIAKNGTLYMKECQASDAGNYTCSVENTWG-KDEIV 1258 Query: 194 ATLKIHIKP 202 + + + P Sbjct: 1259 YNIVVKVPP 1267 >UniRef50_Q58EX2 Cluster: Protein sidekick-2 precursor; n=19; Euteleostomi|Rep: Protein sidekick-2 precursor - Homo sapiens (Human) Length = 2170 Score = 148 bits (359), Expect = 8e-34 Identities = 198/813 (24%), Positives = 318/813 (39%), Gaps = 91/813 (11%) Query: 34 RAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG- 92 R P P + W++ G + + R+I L L V DAG Y+ +A N Sbjct: 136 RIASFPQPQVTWFRDG-RKIPPSSRAITLENTLVILST----VAPDAGRYYVQAVNDKNG 190 Query: 93 -TARSRNATLHVAV------LREEFRLEPESKQSAQGDT-VVLECLP-PRGSPEPNVYWK 143 S+ TL V V + + P++ G + V LEC+ R + ++ WK Sbjct: 191 DNKTSQPITLTVEVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWK 250 Query: 144 KNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI--ATLKIHIK 201 K+G +L G H L I + +DAG Y+C A + + S + A L + Sbjct: 251 KDG--VLLSGGISDH---NRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEP 305 Query: 202 PYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP-LGRVKVLDDGSLRL 259 P + PE + A+ V C+ G P P + W + A + L R + +DG L++ Sbjct: 306 PQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQI 365 Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLSPNSVNVESGNVARFTCTATG 318 ++ D G + C A N+ G V S YL V P+I P V G C +G Sbjct: 366 SGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSG 425 Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378 P P + W +G R + + ++ T + G L I+ T +D+ T C A N Sbjct: 426 APRPAITWQ-KGERILASGSVQLPRF--TPLESGS--LLISPTHISDA-GTYTCLATNSR 479 Query: 379 GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA--WYFEGE 436 G L V + IT P +Q++ + A C P I W +G Sbjct: 480 GVDEASADLVVWARTR-----ITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGA 534 Query: 437 AL-IQNHRR-NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHF 494 L ++H R + +G+L + D GTYTC S G S L Sbjct: 535 TLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHL------------ 582 Query: 495 FRAADVSSLPGPPTKPIT--HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNN 552 V LP P P+ V ++ L+W++ G+S ++ Y +E +S NN Sbjct: 583 ----RVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILE------MSENN 631 Query: 553 TPRNSRGWVVIARRV--HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDD 610 P W V+ V T VK L+P +Y F + N G S ++ V++ ++ Sbjct: 632 AP-----WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEE 686 Query: 611 SNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRP 670 + +++ T+ + + P +S ++ + Y L GL Sbjct: 687 PPTAPPQNVIASGR-------TNQSIMIQWQPPPESHQNGILKGYIIRYCLAGL------ 733 Query: 671 LDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDV 730 + Y+ K I + DV+ + L +T YE + + G S+ TL V Sbjct: 734 ----PVGYQFKNITDA-DVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGV 788 Query: 731 PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH 790 P PP N+ N+TT+ W+ P Q NGI GY ++ + +MV Sbjct: 789 PTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQ 848 Query: 791 QATSL-IMTNLTSGVSYSVQIAAETIIGLGPFS 822 + + ++ L Y + T G GP S Sbjct: 849 DSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRS 881 Score = 127 bits (306), Expect = 2e-27 Identities = 101/332 (30%), Positives = 142/332 (42%), Gaps = 22/332 (6%) Query: 11 APYIIEQPLDVTV-ARHQPATLNCRAGGSPSPAIR--WYKGGVLV---VSDTHRSILPAG 64 AP II P + +V A TL C A P + W K GVL+ +SD +R + Sbjct: 212 APTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGISDHNRRL---- 267 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGD 123 SDAG Y CEA + S +++VL +F EPE +A+ + Sbjct: 268 ------TIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEME 321 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183 VV +G P P++ W K+ + + +R + G L I D G +QC AR Sbjct: 322 KVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFAR 381 Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR---RSAG 240 NAAG +++ I P + GP D G SV C G P P + W+ R Sbjct: 382 NAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILA 441 Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300 G++ L R L+ GSL + ++D G Y+C A NS G AS L V+ I P Sbjct: 442 SGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQ 501 Query: 301 SVNVESGNVARFTCTATGRPEPTM--FWSVEG 330 +V G A C T P T+ W +G Sbjct: 502 DQSVIKGTQASMVCGVTHDPRVTIRYIWEKDG 533 Score = 103 bits (248), Expect = 2e-20 Identities = 81/298 (27%), Positives = 133/298 (44%), Gaps = 17/298 (5%) Query: 5 YVTSGEAPYIIEQP-LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD--THRSIL 61 Y++ E P +++P +T + + C+A G P P+I WYK +V + T Sbjct: 299 YLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQR 358 Query: 62 PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121 GGL G V D G++ C A N+ G ++ + L V + P Sbjct: 359 NDGGL----QISGLVPDDTGMFQCFARNAAGEVQT-STYLAVTSIAPNITRGPLDSTVID 413 Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGD---SRMHLVDGGNLVIQDARQTDAGRY 178 G +VVL C G+P P + W+K G+ +L G R ++ G+L+I +DAG Y Sbjct: 414 GMSVVLAC-ETSGAPRPAITWQK-GERILASGSVQLPRFTPLESGSLLISPTHISDAGTY 471 Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV--LWR 236 C+A N+ G E++ A L + + + P+D G+ + C V DP + +W Sbjct: 472 TCLATNSRGVDEAS-ADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWE 530 Query: 237 RSAGG-GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293 + G R+++ +GSL + D G Y+C ++ G S S +L V P Sbjct: 531 KDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLP 588 Score = 75.4 bits (177), Expect = 9e-12 Identities = 67/208 (32%), Positives = 91/208 (43%), Gaps = 15/208 (7%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR----SILPAGGL 66 AP I PLD TV L C G+P PAI W KG ++ S + + + L +G L Sbjct: 399 APNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSL 458 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126 + TH SDAG Y C ATNS G + +A L V R P+ + +G Sbjct: 459 L-ISPTH---ISDAGTYTCLATNSRGVDEA-SADL-VVWARTRITKPPQDQSVIKGTQAS 512 Query: 127 LECLPPRGSPEPNVY-WKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 + C Y W+K+G TL + R+ L G+L I D G Y C +A Sbjct: 513 MVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISA 572 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVA 213 G +S A L++ P+ PE VA Sbjct: 573 GG-NDSRSAHLRVRQLPH---APEHPVA 596 Score = 74.5 bits (175), Expect = 2e-11 Identities = 84/329 (25%), Positives = 142/329 (43%), Gaps = 26/329 (7%) Query: 504 PGPPTKPITH--NVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV 561 P PP++P+ +V SV LSW + G S + Y ++ +RE SG W Sbjct: 1398 PQPPSRPMVQQEDVRARSVLLSWEPGSD-GLSPVRYYTIQ--TRELPSGR--------WA 1446 Query: 562 VIARRV--HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV----GDDSNSLW 615 + + V + + ++V L P +Y F V+ N G S S S+S+T D++ ++ Sbjct: 1447 LHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTIL 1506 Query: 616 EGTG-VSNSTEYR-NNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDN 673 T + S R D I ++ I + +L++E L + L G+ Sbjct: 1507 SVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYR--ELLYEGLRGFTLRGINNPGATWAE 1564 Query: 674 ITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDG 733 +T Y M+ + + ++ +E+ +L K+ +YE + + EG S + + VP Sbjct: 1565 LTSMYSMRNLSRPS-LTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTA 1623 Query: 734 PPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT 793 P N+ + T + + W PP L QNG I GY + W + + T Sbjct: 1624 APRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYF-W-EAQRGNLTERVKTLFLAEN 1681 Query: 794 SLIMTNLTSGVSYSVQIAAETIIGLGPFS 822 S+ + NLT +Y V +AA G GP S Sbjct: 1682 SVKLKNLTGYTAYMVSVAAFNAAGDGPRS 1710 Score = 70.5 bits (165), Expect = 3e-10 Identities = 101/403 (25%), Positives = 159/403 (39%), Gaps = 48/403 (11%) Query: 110 FRLEPESKQ-SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL-FDGDSRMHLVDGGNLVI 167 F+ EP Q +G+ +VL C+ GS W N + L F + R +I Sbjct: 28 FKTEPVRTQVHLEGNRLVLTCMA-EGSWPLEFKWLHNNRELTKFSLEYRY--------MI 78 Query: 168 QDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC-RVG 226 +T AG Y+CI RN G +++ G + G + + R+ Sbjct: 79 TSLDRTHAGFYRCIVRNRMGALLQRQTEVQVADMGSFEEGEKHQSVSHGEAAVIRAPRIA 138 Query: 227 GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY 286 P P V W R G +P + + +L + + + D G Y +A N + + Sbjct: 139 SFPQPQVTWFRD--GRKIPPSSRAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQ 196 Query: 287 ---LTVY-----DP--PSINLSPNSVNVESG-NVARFTCTATGRP--EPTMFWSVEGNRT 333 LTV DP P+I + P + +V +G + C A RP + + W +G Sbjct: 197 PITLTVEVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDG--- 253 Query: 334 IIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGS--SFVRGKLTVTS 391 ++ G + D LTI + +D+ C AV + S S VRG Sbjct: 254 VLLSG---------GISDHNRRLTIPNPTGSDA-GYYECEAVLRSSSVPSVVRGAYLSVL 303 Query: 392 DDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRR-NVTND 449 + PP + + T ++ + PC A P P I WY + + ++ R ND Sbjct: 304 E---PPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRND 360 Query: 450 GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492 G L + L D+G + C A + G+ S L V S I PNI Sbjct: 361 GGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTS-IAPNI 402 Score = 66.1 bits (154), Expect = 6e-09 Identities = 46/151 (30%), Positives = 69/151 (45%), Gaps = 6/151 (3%) Query: 683 ILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQ-TLDDVPDGPPINIEMF 741 ++ N ++T L KY YE ++ F + +G PS+ + + TLDDVP GPP+ I Sbjct: 1250 LVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVP-GPPMGILFP 1308 Query: 742 ILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLT 801 + TT+V L W PP NGII Y + AN + V + A T L Sbjct: 1309 EVRTTSVRLIWQPP--AAPNGIILAYQITHRLNTTTANTATVEV--LAPSARQYTATGLK 1364 Query: 802 SGVSYSVQIAAETIIGLGPFSQKVYFNIDSR 832 Y +I A+T G G ++ + + R Sbjct: 1365 PESVYLFRITAQTRKGWGEAAEALVVTTEKR 1395 Score = 54.0 bits (124), Expect = 2e-05 Identities = 43/156 (27%), Positives = 70/156 (44%), Gaps = 8/156 (5%) Query: 661 LEGLFIYFRPLDNITIEYEMKTI-LHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPS 719 ++G IYF + +KT+ L N V ++ +L YT Y + F +G S Sbjct: 1654 IQGYKIYFWEAQRGNLTERVKTLFLAENSV---KLKNLTGYTAYMVSVAAFNAAGDGPRS 1710 Query: 720 NSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVN-WLDVPA 778 QT P P +++ L TT+V++ W P Q NGI+ GY +V V Sbjct: 1711 TPTQGQTQQAAPSAPS-SVKFSELTTTSVNVSWEAP--QFPNGILEGYRLVYEPCSPVDG 1767 Query: 779 NKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAET 814 +V ++ + L + +L GV+Y +I A+T Sbjct: 1768 VSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKT 1803 Score = 53.2 bits (122), Expect = 4e-05 Identities = 48/192 (25%), Positives = 93/192 (48%), Gaps = 17/192 (8%) Query: 639 IEATPIDSKTIKLMWEILNFYYLEGL-----FIYFRPL--DNITIEYEMKTILHSNDVSG 691 + A +S TI+ W + ++ G+ I + P + +T+ S V G Sbjct: 796 VHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHV-G 854 Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751 F ++ L+K+T+Y ++ F +G S ++ +T +DVP GP ++ + T++ + Sbjct: 855 F-VSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVP-GPVGHLSFSEILDTSLKVS 912 Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT-SLIMTNLTSGVSYSVQI 810 W P +NGI+TGY ++W + N++ + + T +T LT+ +Y++++ Sbjct: 913 WQEP--GEKNGILTGYR--ISWEEY--NRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEV 966 Query: 811 AAETIIGLGPFS 822 AA T G G S Sbjct: 967 AAMTSKGQGQVS 978 Score = 52.0 bits (119), Expect = 1e-04 Identities = 40/141 (28%), Positives = 59/141 (41%), Gaps = 5/141 (3%) Query: 688 DVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN-SRVAQTLDDVPDGPPINIEMFILNTT 746 D E+ L +T Y F + PS SR QTL PD P N+ + + T Sbjct: 1050 DARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASET 1109 Query: 747 TVHLKWSP-PELQLQ-NGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGV 804 ++ L+W P PE++ N GY + + D + V + + +L Sbjct: 1110 SLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVER--DYTIEDLEEWT 1167 Query: 805 SYSVQIAAETIIGLGPFSQKV 825 Y VQ+ A IG GP+SQ V Sbjct: 1168 EYRVQVQAFNAIGSGPWSQTV 1188 Score = 50.8 bits (116), Expect = 2e-04 Identities = 33/124 (26%), Positives = 56/124 (45%), Gaps = 3/124 (2%) Query: 703 YEFFLIPFYKKFEGKPSNSRVAQTL-DDVPDGPPINIEMFILNTTTVHLKWSPPELQLQN 761 Y+F L +G+ S +L ++ P PP N+ ++ ++W PP QN Sbjct: 659 YQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQN 718 Query: 762 GIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPF 821 GI+ GY + +P N T +L++ +L +Y +++AA GLG + Sbjct: 719 GILKGYIIRYCLAGLPVGYQFK--NITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVY 776 Query: 822 SQKV 825 S KV Sbjct: 777 SSKV 780 Score = 49.2 bits (112), Expect = 7e-04 Identities = 33/128 (25%), Positives = 57/128 (44%), Gaps = 2/128 (1%) Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751 + I L ++T+Y + F G S + V +T + VP P N+ ++++ ++ Sbjct: 1158 YTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVR 1217 Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811 WS +NG++ GY V+ D + + + S +T L V Y VQ+ Sbjct: 1218 WSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEG--NSSRSAQLTGLGKYVLYEVQVL 1275 Query: 812 AETIIGLG 819 A T IG G Sbjct: 1276 AFTRIGDG 1283 >UniRef50_UPI0000E80BF7 Cluster: PREDICTED: similar to bone specific CMF608; n=2; Gallus gallus|Rep: PREDICTED: similar to bone specific CMF608 - Gallus gallus Length = 1817 Score = 148 bits (358), Expect = 1e-33 Identities = 174/631 (27%), Positives = 266/631 (42%), Gaps = 66/631 (10%) Query: 12 PYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWY--KGGV---LVVSDTHRSILPAGG 65 P I+E+ + Q L C A G+P P + W KG L +T +LP G Sbjct: 1036 PIILEEKRQQIAATAGQDLNLPCTAEGNPQPHVHWVLSKGTAVKPLQFVNTRVLLLPNGT 1095 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---G 122 L V +D+G Y C AT+S G+ R R L V R+ S+ Q G Sbjct: 1096 L----QLSSIVPADSGNYECIATSSTGSER-RVVILTVRHRDTLPRIAAASQGMTQLSFG 1150 Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGD---SRMHLVDGGNLVIQDARQTDAGRYQ 179 D ++L C G P+P + W+ + ++ SR+H+ G+LVI+ + DAG Y Sbjct: 1151 DKLLLNCTAT-GEPQPRIMWRLPSKAVVDQWHRMGSRIHVYPNGSLVIEAVTEKDAGDYL 1209 Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 C+ARN G + + + I +KP I + + G C+ G P P++ W Sbjct: 1210 CVARNKIGD-DLILMKVSITMKPAKIDQKQYFKKLVPYGKDFQVDCKASGSPAPEISWSL 1268 Query: 238 SAGG--GNMPLG--------RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYL 287 G N L R + D+G+L L+ + +EG+Y+C A+NS+G ++ Sbjct: 1269 PDGMVINNAMLADDSGHRARRYVLFDNGTLYLNRAGVTEEGDYTCYAQNSLGRDEMKIHV 1328 Query: 288 TVYDP-PSINLSPNS-VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345 TV P I S + V V++G+ A C A G P+P +FW + + I S D+ H Sbjct: 1329 TVVTAAPQIKHSYKTYVKVKAGDTALLDCEAAGEPKPKIFWLLPSSDII---SSSTDR-H 1384 Query: 346 ATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPS 405 V ++V D + +C A N G KL V D PPII + Sbjct: 1385 LLHVNGSLSVRRAKLLDAGE----YMCVARNAGGDDTKLYKLDV----DAKPPIINGLYT 1436 Query: 406 NQTLPIKSMAV------FPCTAICTPEPIIAWYFEGEALIQ----NHRRNVTNDGTLVLK 455 N+T+ IK AV C A TP P I W + R + +GTL ++ Sbjct: 1437 NKTI-IKVTAVRHSKKQIDCRAEGTPPPQIMWIMPDNIFLTAPYYGSRIVIHKNGTLEIR 1495 Query: 456 DLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNV 515 +L SD+ + CVA + G+ V L V + + F+ + P K IT N Sbjct: 1496 NLRPSDTADFICVARNDWGESVLVVRLEVLEMLRRPM--FKNPFNEKIIAKPGKTITLNC 1553 Query: 516 T---DTSVTLSWSQNNKIGSSSILGY-QVEVFSRETLSGNNTPRNSRGWVVIARRVHQTH 571 + + +SW N + S G + S TLS N R+ G A + +Q Sbjct: 1554 SVDGNPPPEVSWMLPNGMWLSKGTGTPEFLPGSNGTLSIRNPSRDKAGKYRCAAK-NQVG 1612 Query: 572 YVVKSLIPGITYMFIVRTENS---HGLSGPS 599 Y+ K ++ + + T G+SG S Sbjct: 1613 YIEKLIVLEVAQKPTILTHPKGPMRGISGES 1643 Score = 146 bits (354), Expect = 3e-33 Identities = 131/480 (27%), Positives = 192/480 (40%), Gaps = 40/480 (8%) Query: 22 TVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSDTHRSILPAGGLFFLRATHGRVHS 78 TV + A + C A G+P P I W K S + ++LP G L +A Sbjct: 856 TVLANSDAFIPCEATGNPQPTIEWTKMSPDTDAPASGSRWTVLPNGTLAIAQA----ALQ 911 Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138 D G Y C ATN GTAR ATL V + G V + C P G P P Sbjct: 912 DGGQYRCTATNVLGTARLL-ATLAVVAYPPRIAGSTRLLTAHAGMPVAMRC-PAEGRPPP 969 Query: 139 NVYW-KKNGQ--TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195 ++ W NG + G+ ++ + G L I+D D G Y C A N AGT + Sbjct: 970 SISWVLANGTHVSSSSQGNQKVLVRPDGTLTIKDVTVYDRGLYTCTATNPAGTDALTVKL 1029 Query: 196 LKIHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL----GRVK 250 I P ++ +A T G + C G+P P V W S G PL RV Sbjct: 1030 QVIAAPPIILEEKRQQIAATAGQDLNLPCTAEGNPQPHVHWVLSKGTAVKPLQFVNTRVL 1089 Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD----PPSINLSPNSVNVES 306 +L +G+L+L +++ AD G Y C A +S G+ LTV P S + Sbjct: 1090 LLPNGTLQLSSIVPADSGNYECIATSSTGSERRVVILTVRHRDTLPRIAAASQGMTQLSF 1149 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 G+ CTATG P+P + W + + + H + + + + D D Sbjct: 1150 GDKLLLNCTATGEPQPRIMWRLPSKAVVDQWHRMGSRIHVYP-NGSLVIEAVTEKDAGD- 1207 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426 +C A N G + K+++T +P I + +P C A +P Sbjct: 1208 ---YLCVARNKIGDDLILMKVSITM---KPAKIDQKQYFKKLVPYGKDFQVDCKASGSPA 1261 Query: 427 PIIAWYFEGEALIQN--------HRRN---VTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 P I+W +I N HR + ++GTL L ++ G YTC A + G+ Sbjct: 1262 PEISWSLPDGMVINNAMLADDSGHRARRYVLFDNGTLYLNRAGVTEEGDYTCYAQNSLGR 1321 Score = 130 bits (313), Expect = 3e-28 Identities = 127/477 (26%), Positives = 199/477 (41%), Gaps = 38/477 (7%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRWY-KGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 V V A L+C A G P P I W ++ S T R +L G +R D Sbjct: 1345 VKVKAGDTALLDCEAAGEPKPKIFWLLPSSDIISSSTDRHLLHVNGSLSVRRAK---LLD 1401 Query: 80 AGVYWCEATNSYGTARSR---NATLHVAVLREEFRLEPESKQSA-QGDTVVLECLPPRGS 135 AG Y C A N+ G + ++ + + K +A + ++C G+ Sbjct: 1402 AGEYMCVARNAGGDDTKLYKLDVDAKPPIINGLYTNKTIIKVTAVRHSKKQIDCRA-EGT 1460 Query: 136 PEPNVYWKKNGQTLLFDG--DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193 P P + W L SR+ + G L I++ R +D + C+ARN G + Sbjct: 1461 PPPQIMWIMPDNIFLTAPYYGSRIVIHKNGTLEIRNLRPSDTADFICVARNDWGESVLVV 1520 Query: 194 A--TLKIHIKPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG-NMPLGR 248 L++ +P + P E ++A+ G ++T C V G+P P+V W G + G Sbjct: 1521 RLEVLEMLRRP-MFKNPFNEKIIAKPGKTITLNCSVDGNPPPEVSWMLPNGMWLSKGTGT 1579 Query: 249 VKVL--DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS-VNVE 305 + L +G+L + N G+Y C A+N VG + L V P+I P + Sbjct: 1580 PEFLPGSNGTLSIRNPSRDKAGKYRCAAKNQVGYIEKLIVLEVAQKPTILTHPKGPMRGI 1639 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365 SG C + G P+P+ W++ G + R + ++ + L I +D Sbjct: 1640 SGESLSLHCLSDGSPKPSTAWTLPGGHVL-----DRPQINSRHILLENGTLVIRAATIHD 1694 Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICT 424 R VC A N AG + +T+ + PP ITN P + AV CTA+ Sbjct: 1695 -RGNYVCRAHNPAGDFSITIPVTIVAY----PPRITNRPPQTIHTMPGAAVQLSCTALGI 1749 Query: 425 PEPIIAWYFEGEALIQ--NHRRNVTND-----GTLVLKDLDKSDSGTYTCVASSRHG 474 P P I W +++ NH R ++ GTL +++ SDSGTY C A + G Sbjct: 1750 PRPEITWELPDHSILSTGNHGRASGSELLHPQGTLRIQNPQPSDSGTYKCTARNHLG 1806 Score = 125 bits (302), Expect = 6e-27 Identities = 100/377 (26%), Positives = 166/377 (44%), Gaps = 21/377 (5%) Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTH---RSILPAGGLFFLRATHGR 75 + VT RH ++CRA G+P P I W + ++ + R ++ G +R Sbjct: 1441 IKVTAVRHSKKQIDCRAEGTPPPQIMWIMPDNIFLTAPYYGSRIVIHKNGTLEIRNLR-- 1498 Query: 76 VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ--SAQGDTVVLECLPPR 133 SD + C A N +G + + +LR P +++ + G T+ L C Sbjct: 1499 -PSDTADFICVARNDWGESVLVVRLEVLEMLRRPMFKNPFNEKIIAKPGKTITLNC-SVD 1556 Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGTRES 191 G+P P V W L G + G G L I++ + AG+Y+C A+N G E Sbjct: 1557 GNPPPEVSWMLPNGMWLSKGTGTPEFLPGSNGTLSIRNPSRDKAGKYRCAAKNQVGYIEK 1616 Query: 192 AIATLKIHIKPYLITGPEDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSAGGG-NMPL--G 247 I L++ KP ++T P+ + +G S++ C G P P W G + P Sbjct: 1617 LI-VLEVAQKPTILTHPKGPMRGISGESLSLHCLSDGSPKPSTAWTLPGGHVLDRPQINS 1675 Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV--YDPPSINLSPNSVNVE 305 R +L++G+L + + D G Y C A N G S + +T+ Y P N P +++ Sbjct: 1676 RHILLENGTLVIRAATIHDRGNYVCRAHNPAGDFSITIPVTIVAYPPRITNRPPQTIHTM 1735 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365 G + +CTA G P P + W + + +I+ G + + + + L I + +D Sbjct: 1736 PGAAVQLSCTALGIPRPEITWELP-DHSILSTG-NHGRASGSELLHPQGTLRIQNPQPSD 1793 Query: 366 SRNTIVCSAVNYAGSSF 382 S T C+A N+ GS F Sbjct: 1794 S-GTYKCTARNHLGSDF 1809 Score = 114 bits (275), Expect = 1e-23 Identities = 122/480 (25%), Positives = 199/480 (41%), Gaps = 56/480 (11%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDT-------HRS----ILPAGGLFFLRATHGRVHSD 79 ++C+A GSP+P I W +V+++ HR+ + G L+ RA ++ Sbjct: 1252 VDCKASGSPAPEISWSLPDGMVINNAMLADDSGHRARRYVLFDNGTLYLNRAGV----TE 1307 Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GDTVVLECLPPRGSP 136 G Y C A NS G + +HV V+ +++ K + GDT +L+C G P Sbjct: 1308 EGDYTCYAQNSLGRDEMK---IHVTVVTAAPQIKHSYKTYVKVKAGDTALLDC-EAAGEP 1363 Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196 +P ++W ++ R L G+L ++ A+ DAG Y C+ARNA G ++ + L Sbjct: 1364 KPKIFWLLPSSDIISSSTDRHLLHVNGSLSVRRAKLLDAGEYMCVARNAGGD-DTKLYKL 1422 Query: 197 KIHIKPYLITGPE------DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG-GGNMPL--G 247 + KP +I G V A S CR G P P ++W P Sbjct: 1423 DVDAKPPIINGLYTNKTIIKVTAVRHSKKQIDCRAEGTPPPQIMWIMPDNIFLTAPYYGS 1482 Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD----PPSINLSPNSVN 303 R+ + +G+L + N+ +D ++ C A N G L V + P N + Sbjct: 1483 RIVIHKNGTLEIRNLRPSDTADFICVARNDWGESVLVVRLEVLEMLRRPMFKNPFNEKII 1542 Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF--DGVTVLTINDT 361 + G C+ G P P + W + GM K T F L+I + Sbjct: 1543 AKPGKTITLNCSVDGNPPPEVSWMLPN-------GMWLSKGTGTPEFLPGSNGTLSIRNP 1595 Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCT 420 + D C+A N G ++ KL V + + P I+T+ P I ++ C Sbjct: 1596 SR-DKAGKYRCAAKNQVG--YIE-KLIVL-EVAQKPTILTH-PKGPMRGISGESLSLHCL 1649 Query: 421 AICTPEPIIAWYFEGEALIQ----NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476 + +P+P AW G ++ N R + +GTLV++ D G Y C A + G + Sbjct: 1650 SDGSPKPSTAWTLPGGHVLDRPQINSRHILLENGTLVIRAATIHDRGNYVCRAHNPAGDF 1709 Score = 111 bits (267), Expect = 1e-22 Identities = 122/478 (25%), Positives = 195/478 (40%), Gaps = 36/478 (7%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRS-----ILPAGGLFFLRATHGR 75 +T P + C A G P P+I W VS + + + P G L T Sbjct: 949 LTAHAGMPVAMRCPAEGRPPPSISWVLANGTHVSSSSQGNQKVLVRPDGTLTIKDVT--- 1005 Query: 76 VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA--QGDTVVLECLPPR 133 V+ D G+Y C ATN GT + L V + LE + +Q A G + L C Sbjct: 1006 VY-DRGLYTCTATNPAGT-DALTVKLQV-IAAPPIILEEKRQQIAATAGQDLNLPC-TAE 1061 Query: 134 GSPEPNVYW---KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT-R 189 G+P+P+V+W K L ++R+ L+ G L + D+G Y+CIA ++ G+ R Sbjct: 1062 GNPQPHVHWVLSKGTAVKPLQFVNTRVLLLPNGTLQLSSIVPADSGNYECIATSSTGSER 1121 Query: 190 ESAIATLKIHIKPYLITGPEDVVAQT--GSSVTFQCRVGGDPLPDVLWRRSAGG----GN 243 I T++ I + Q G + C G+P P ++WR + + Sbjct: 1122 RVVILTVRHRDTLPRIAAASQGMTQLSFGDKLLLNCTATGEPQPRIMWRLPSKAVVDQWH 1181 Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV-YDPPSINLSPNSV 302 R+ V +GSL ++ V D G+Y C A N +G +++ P I+ Sbjct: 1182 RMGSRIHVYPNGSLVIEAVTEKDAGDYLCVARNKIGDDLILMKVSITMKPAKIDQKQYFK 1241 Query: 303 N-VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT---AVFDGVTVLTI 358 V G + C A+G P P + WS+ I ++ D H +FD T L + Sbjct: 1242 KLVPYGKDFQVDCKASGSPAPEISWSLPDGMVINNAMLADDSGHRARRYVLFDNGT-LYL 1300 Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418 N + C A N G ++ +TV + P I + + + A+ Sbjct: 1301 NRAGVTE-EGDYTCYAQNSLGRDEMKIHVTVVT---AAPQIKHSYKTYVKVKAGDTALLD 1356 Query: 419 CTAICTPEPIIAWYFEGEALIQN--HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 C A P+P I W +I + R + +G+L ++ D+G Y CVA + G Sbjct: 1357 CEAAGEPKPKIFWLLPSSDIISSSTDRHLLHVNGSLSVRRAKLLDAGEYMCVARNAGG 1414 Score = 89.4 bits (212), Expect = 5e-16 Identities = 77/272 (28%), Positives = 109/272 (40%), Gaps = 17/272 (6%) Query: 30 TLNCRAGGSPSPAIRWY-KGGVLVVSDTHR-SILP-AGGLFFLRATHGRVHSDAGVYWCE 86 TLNC G+P P + W G+ + T LP + G +R AG Y C Sbjct: 1550 TLNCSVDGNPPPEVSWMLPNGMWLSKGTGTPEFLPGSNGTLSIRNPS---RDKAGKYRCA 1606 Query: 87 ATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146 A N G + L VA + G+++ L CL GSP+P+ W G Sbjct: 1607 AKNQVGYIE-KLIVLEVAQKPTILTHPKGPMRGISGESLSLHCLSD-GSPKPSTAWTLPG 1664 Query: 147 QTLLFDG--DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL 204 +L +SR L++ G LVI+ A D G Y C A N AG I + P + Sbjct: 1665 GHVLDRPQINSRHILLENGTLVIRAATIHDRGNYVCRAHNPAGDFSITIPVTIVAYPPRI 1724 Query: 205 ITGPEDVV-AQTGSSVTFQCRVGGDPLPDVLWR------RSAGGGNMPLGRVKVLDDGSL 257 P + G++V C G P P++ W S G G + G+L Sbjct: 1725 TNRPPQTIHTMPGAAVQLSCTALGIPRPEITWELPDHSILSTGNHGRASGSELLHPQGTL 1784 Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 R+ N +D G Y C A N +G+ Y+ V Sbjct: 1785 RIQNPQPSDSGTYKCTARNHLGSDFTVTYIHV 1816 Score = 61.3 bits (142), Expect = 2e-07 Identities = 42/170 (24%), Positives = 74/170 (43%), Gaps = 9/170 (5%) Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 G + C A G P P + W + + P +S D V G L DT Sbjct: 524 GGTVQLDCQAIGEPAPAIEWILADGSKVRAPYVSEDG-RIIVVKSGTFTLRTADTFDTGL 582 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426 + C NY + + ++TV D NG + + + S+ PCT+ P+ Sbjct: 583 YH---CIGTNYNDADILTFRITVV--DPYVEHSSVNG-AQLSAAVGSILDLPCTSTAVPD 636 Query: 427 PIIAWYFEGEALIQNHRRN--VTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 ++W ++ + RN + ++GTL ++ + + DSG + CVA+S++G Sbjct: 637 AAVSWVLPERVVLHHSVRNRHIFDNGTLRIQGVTERDSGYFRCVAASQYG 686 Score = 55.2 bits (127), Expect = 1e-05 Identities = 47/163 (28%), Positives = 67/163 (41%), Gaps = 11/163 (6%) Query: 31 LNCRAGGSPSPAIRWY-----KGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85 L+C+A G P+PAI W K VS+ R I+ G F LR D G+Y C Sbjct: 529 LDCQAIGEPAPAIEWILADGSKVRAPYVSEDGRIIVVKSGTFTLRTADT---FDTGLYHC 585 Query: 86 EATNSYGTARSRNATLHVA-VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK 144 TN Y A + V E + +A G + L C P+ V W Sbjct: 586 IGTN-YNDADILTFRITVVDPYVEHSSVNGAQLSAAVGSILDLPCTST-AVPDAAVSWVL 643 Query: 145 NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 + +L H+ D G L IQ + D+G ++C+A + G Sbjct: 644 PERVVLHHSVRNRHIFDNGTLRIQGVTERDSGYFRCVAASQYG 686 Score = 49.6 bits (113), Expect = 5e-04 Identities = 49/193 (25%), Positives = 80/193 (41%), Gaps = 15/193 (7%) Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGG-NMPL----GRVKVLDDGSLRLDNVILADEGEY 270 G +V C+ G+P P + W + G P GR+ V+ G+ L D G Y Sbjct: 524 GGTVQLDCQAIGEPAPAIEWILADGSKVRAPYVSEDGRIIVVKSGTFTLRTADTFDTGLY 583 Query: 271 SCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES--GNVARFTCTATGRPEPTMFWSV 328 C N A + +TV DP + S N + + G++ CT+T P+ + W V Sbjct: 584 HCIGTNYNDADILTFRITVVDPYVEHSSVNGAQLSAAVGSILDLPCTSTAVPDAAVSW-V 642 Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT 388 R ++ + R+++ +FD T L I + DS C A + G + ++ Sbjct: 643 LPERVVLHHSV-RNRH----IFDNGT-LRIQGVTERDS-GYFRCVAASQYGVDLLVFQVL 695 Query: 389 VTSDDDRPPPIIT 401 V D P + T Sbjct: 696 VRKDKSTPQEVPT 708 Score = 43.6 bits (98), Expect = 0.034 Identities = 44/168 (26%), Positives = 69/168 (41%), Gaps = 15/168 (8%) Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTL---LFDGDSRMHLVDGGNLVIQDARQTDAGR 177 G TV L+C G P P + W +G + D R+ +V G ++ A D G Sbjct: 524 GGTVQLDC-QAIGEPAPAIEWILADGSKVRAPYVSEDGRIIVVKSGTFTLRTADTFDTGL 582 Query: 178 YQCIARNAAGTRESAIATLKIHI-KPYL----ITGPEDVVAQTGSSVTFQCRVGGDPLPD 232 Y CI N ++ I T +I + PY+ + G + + A GS + C P Sbjct: 583 YHCIGTNY---NDADILTFRITVVDPYVEHSSVNGAQ-LSAAVGSILDLPCTSTAVPDAA 638 Query: 233 VLWRRSAGGG-NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279 V W + + + D+G+LR+ V D G + C A + G Sbjct: 639 VSWVLPERVVLHHSVRNRHIFDNGTLRIQGVTERDSGYFRCVAASQYG 686 Score = 36.3 bits (80), Expect = 5.1 Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 3/78 (3%) Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF---EGEALIQNHRRNVTNDGTLV 453 P II + T+ S A PC A P+P I W + +A R V +GTL Sbjct: 845 PRIIGGKLAAFTVLANSDAFIPCEATGNPQPTIEWTKMSPDTDAPASGSRWTVLPNGTLA 904 Query: 454 LKDLDKSDSGTYTCVASS 471 + D G Y C A++ Sbjct: 905 IAQAALQDGGQYRCTATN 922 >UniRef50_UPI0000D56997 Cluster: PREDICTED: similar to CG8581-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG8581-PA, isoform A - Tribolium castaneum Length = 1429 Score = 147 bits (357), Expect = 1e-33 Identities = 202/834 (24%), Positives = 323/834 (38%), Gaps = 81/834 (9%) Query: 8 SGEAPYIIEQPLDVTVARHQPATLNC--RAGGSPSPAIRWY---KGGVLVVSDTHRSILP 62 SG +P D V Q A L+C ++ S I+W + + + D +RS L Sbjct: 2 SGHVLEFTVEPTDTVVESGQSAVLDCVIKSSHPASVLIQWLDQDRQKLTYLGDLYRSQLT 61 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEAT-NSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121 G L+ + + G Y C A+ + G+ S+ ATL+VA + F EP + + Sbjct: 62 NGSLYINSVLEEQRLT--GTYQCMASLPNVGSIVSKAATLNVASI-SGFLEEPRDLRVYE 118 Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181 G C +P + W K+ + L D + RM L+ G L I + ++D G Y+C Sbjct: 119 GQRAHFACHVV-AAPPAKIRWLKDERPLQID-ELRMTLLPSGALEIDEVAESDQGAYRCN 176 Query: 182 ARNAAGTRESAIATLKIH--------IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233 A + S ATL + + P I P+ V G +V+ C G P P + Sbjct: 177 ATGLNLYKLSNKATLTVSGDREEAHFVPPTFIARPKSAVVVEGQNVSLDCAANGYPHPSI 236 Query: 234 LWRRSAGGGNMPL--GRV-KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290 W + +M R KV SLR+ N+ D G Y C A N ++ AS + V Sbjct: 237 TWLKDGSTIDMTFLDSRFSKVGSTSSLRITNIKEEDAGTYQCRAANREDSLDASATIQVQ 296 Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350 PP P + C+ G PEP + W +G I S D Y + Sbjct: 297 VPPRFRKKPQDKIENANKDIELECSVYGNPEPKISWFKDGEAII-----SNDYYQ---IV 348 Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410 +G L I +DS C A N AG+ L V + P N+ P Sbjct: 349 NGHN-LKIMGLMPSDS-GIFQCFASNPAGNIQAAASLKVLNPG---PKKRKKSKKNRDNP 403 Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470 I M F + P+ A + + R+N D + + + ++ + S Sbjct: 404 IDQMQSFTLFSHLKPDSS-ARLGDVDFGHFARRKNFMQDSSSSSQTI-YDPQRAFSSLKS 461 Query: 471 SRHGKYVWSG----ALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQ 526 S + G A S + A PGPP V VTLSW + Sbjct: 462 SESYDNINLGDTQHAFFPPSSTSITAESSVAKTTEGFPGPPQDLKAPIVKARFVTLSW-R 520 Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFI 586 + S +I Y V + +E SR R+ + + + L P Y F Sbjct: 521 APLVNSDNIHTYTV-YYRQEGSERWRVQNTSRS------RLEEIN--IAGLTPSKVYHFR 571 Query: 587 VRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDS 646 V NS G +G S S+S+TV S + ++ Y + T ++ TP + Sbjct: 572 VVAINSVG-AGVS--SESLTVTTQSEE-HVASAPTHFVAYATSPRTIYLNWRPPETP-NG 626 Query: 647 KTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFF 706 ++ M YY+E +D ++Y + L YT+Y + Sbjct: 627 NILRYM-----VYYMETSSSVEHNIDTTELKYHL--------------VGLSVYTEYSVW 667 Query: 707 LIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITG 766 ++ + G ++ ++ +TL P PP NI + +TT + ++W PP + QNG+ITG Sbjct: 668 VVAVNENGPGAATDEKIVRTLSASPSEPPSNITLEPTSTTVI-VRWEPPPPEYQNGVITG 726 Query: 767 YNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGP 820 Y + K V + T+ ++ ++ +L G Y V++ A + G P Sbjct: 727 YKLKYR----KQGKKGVTVTTSANE-RFYVLNDLERGAEYQVKLWAINVNGTSP 775 Score = 51.2 bits (117), Expect = 2e-04 Identities = 58/236 (24%), Positives = 98/236 (41%), Gaps = 14/236 (5%) Query: 675 TIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQ-TLDDVPDG 733 T E M+T + I L+ T YEF + K + P + V T + P+ Sbjct: 940 TAERTMRTRTVNVSDLNVMIDDLKPNTLYEF-AVKLVKGRKESPWSMVVQNATWELAPNA 998 Query: 734 PPINIEMFILNTTT--VHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQ 791 P ++++ + V L W PP++ +G ITGY ++ +++ +A T Sbjct: 999 SPRDLDVHLKEDEPQLVELTWQPPKIT--SGRITGYVILYTDNKTKSDREWLA-QATKGD 1055 Query: 792 ATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIV 851 S ++ +L Y ++ A G GPFS V F S L SR ++G+ I Sbjct: 1056 KHSAVLGDLKPNTEYYFKVQARNSKGYGPFSNVVIFTTGSNVGTLVSSSRQHLDGK-GIF 1114 Query: 852 AGDFVMETWFYFLIGA--IVLFKIIVIAGIIYVRKYNIFAKKSALPNIYDSNGTSL 905 +G ++ YFLIG I + I V+ ++ R+ + A Y S+ Sbjct: 1115 SGTVII----YFLIGGCIIAVTTIGVVTTVLCCRRRDAAASPDRSKKGYQKGNQSV 1166 >UniRef50_Q59E65 Cluster: CG33519-PB; n=5; Sophophora|Rep: CG33519-PB - Drosophila melanogaster (Fruit fly) Length = 4129 Score = 147 bits (357), Expect = 1e-33 Identities = 152/630 (24%), Positives = 258/630 (40%), Gaps = 60/630 (9%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL--PAGGLFFL 69 P ++ TV +P L + G P+P ++WYK G+L+ + + P G + + Sbjct: 2229 PKFLKPITSQTVVVGEPLKLEAQVTGFPAPEVKWYKDGMLLRPSPEINFINSPNGQIGLI 2288 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARS-RNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128 DAGVY C N G + + F E + S +G V ++ Sbjct: 2289 --IDAAQPLDAGVYKCLIANKGGEIEGVSKVEIVPKESKPVFVAELQDASSIEGFPVKMD 2346 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD----GGNLVIQDARQTDAGRYQCIARN 184 + G+P+P + W NG + D S + +V+ +L+I+ D+G Y+ IA+N Sbjct: 2347 -IKVVGNPKPKLQWFHNGHEIKPDA-SHIAIVENPDNSSSLIIEKTAPGDSGLYEVIAQN 2404 Query: 185 AAGTRESAIATLKIHIK---------PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235 G+ S A L + K P ++ DV A G + +P+P+V+W Sbjct: 2405 PEGSTASK-AKLYVAPKADETATEEAPQFVSALRDVNADEGQELVLSAPFISNPMPEVIW 2463 Query: 236 RRSAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSA---SGYLTV 289 + G P R+ + DG L + AD G Y+C N +G S+ + V Sbjct: 2464 SKD-GVTLTPNERLLMTCDGKHIGLTIKPAEAADSGNYTCLLANPLGEDSSACNANVRKV 2522 Query: 290 YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349 Y PP + GN A+ T +G P P + W + P +KY Sbjct: 2523 YKPPVFTQKISDQQQVFGNNAKIPVTVSGVPYPDLEWYFQDK-----PIPKSEKYSIKND 2577 Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR----PPPIITNGPS 405 D +L +N+ +K D + C A N G +G+L + ++ + PP+ Sbjct: 2578 GDH-HMLIVNNCEKGD-QGVYKCIASNREGKDITQGRLDIVNEIKKHSRSEPPVFLKKIG 2635 Query: 406 NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR--RNVTNDG--TLVLKDLDKSD 461 + + +A F A PEP + W+ + L + R ++ +G L +K++ + D Sbjct: 2636 DCDIYEGMVAKFTACATGYPEPEVEWFKNDQKLFPSDRFLIDIEPNGLLRLTIKNVTEYD 2695 Query: 462 SGTYTCVASSRHGKYVWSGALLVDS------PINPNIHFFRAADVSSLPGPPTK-PITHN 514 G Y+C + +G + L DS P+ F+ S P P ++ PI Sbjct: 2696 VGRYSCRIFNPYGDDICHAELFYDSLDSQQKPLEDQYTDFKKYKKSGAPPPLSEGPIISR 2755 Query: 515 VTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVV 574 +TD + LSW+ + + + YQ+E+ + P W + V + Sbjct: 2756 MTDRGLLLSWNPSVPLTPRYPITYQIEMM--------DLPEGD--WRTLRTGVRSCACDI 2805 Query: 575 KSLIPGITYMFIVRTENSHGLSGPSPVSDS 604 ++L P Y F VR EN G+S PSP + + Sbjct: 2806 RNLEPFRDYRFRVRVENKFGVSDPSPYTQT 2835 Score = 130 bits (314), Expect = 2e-28 Identities = 126/488 (25%), Positives = 205/488 (42%), Gaps = 45/488 (9%) Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGLFFLRATHGRVHSDAG 81 V + +P L C GSP P ++W K G V S++ + GL L + + D+G Sbjct: 2143 VLQGEPLVLECCVDGSPLPTVQWLKDGDEVKPSESIKISTNPDGLVKLEINSCQPN-DSG 2201 Query: 82 VYWCEATNSYGTARSRNATLHVAVLREEFR---LEPESKQSAQ-GDTVVLECLPPRGSPE 137 Y +N +G + A VAV EE + L+P + Q+ G+ + LE G P Sbjct: 2202 AYKLIISNPHG---EKVALCAVAVKPEEMQPKFLKPITSQTVVVGEPLKLEA-QVTGFPA 2257 Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGN----LVIQDARQTDAGRYQCIARNAAGTRE--S 191 P V W K+G +L ++ ++ N L+I A+ DAG Y+C+ N G E S Sbjct: 2258 PEVKWYKDG--MLLRPSPEINFINSPNGQIGLIIDAAQPLDAGVYKCLIANKGGEIEGVS 2315 Query: 192 AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251 + + KP + +D + G V +V G+P P + W + + + Sbjct: 2316 KVEIVPKESKPVFVAELQDASSIEGFPVKMDIKVVGNPKPKLQWFHNGHEIKPDASHIAI 2375 Query: 252 LDD----GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---------DPPSINLS 298 +++ SL ++ D G Y A+N G+ ++ L V + P + Sbjct: 2376 VENPDNSSSLIIEKTAPGDSGLYEVIAQNPEGSTASKAKLYVAPKADETATEEAPQFVSA 2435 Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV-LT 357 VN + G + P P + WS +G + P ++ T DG + LT Sbjct: 2436 LRDVNADEGQELVLSAPFISNPMPEVIWSKDG--VTLTPN---ERLLMTC--DGKHIGLT 2488 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417 I + DS N C N G V PP+ T S+Q + A Sbjct: 2489 IKPAEAADSGN-YTCLLANPLGEDSSACNANVRKV--YKPPVFTQKISDQQQVFGNNAKI 2545 Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHG 474 P T P P + WYF+ + + ++ + ++ NDG L++ + +K D G Y C+AS+R G Sbjct: 2546 PVTVSGVPYPDLEWYFQDKPIPKSEKYSIKNDGDHHMLIVNNCEKGDQGVYKCIASNREG 2605 Query: 475 KYVWSGAL 482 K + G L Sbjct: 2606 KDITQGRL 2613 Score = 97.1 bits (231), Expect = 3e-18 Identities = 106/422 (25%), Positives = 169/422 (40%), Gaps = 37/422 (8%) Query: 4 DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-THRSILP 62 + V P + + D + P ++ + G+P P ++W+ G + D +H +I+ Sbjct: 2318 EIVPKESKPVFVAELQDASSIEGFPVKMDIKVVGNPKPKLQWFHNGHEIKPDASHIAIVE 2377 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE--PE----- 115 D+G+Y A N G+ S+ A L+VA +E E P+ Sbjct: 2378 NPDNSSSLIIEKTAPGDSGLYEVIAQNPEGSTASK-AKLYVAPKADETATEEAPQFVSAL 2436 Query: 116 -SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQ 172 + +G +VL P +P P V W K+G TL + + DG + L I+ A Sbjct: 2437 RDVNADEGQELVLSA-PFISNPMPEVIWSKDGVTLT-PNERLLMTCDGKHIGLTIKPAEA 2494 Query: 173 TDAGRYQCIARNAAGTRESAI-ATLKIHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPL 230 D+G Y C+ N G SA A ++ KP + T D G++ V G P Sbjct: 2495 ADSGNYTCLLANPLGEDSSACNANVRKVYKPPVFTQKISDQQQVFGNNAKIPVTVSGVPY 2554 Query: 231 PDVLWRRSAGGGNMPLG-RVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGY 286 PD+ W +P + + +DG L ++N D+G Y C A N G G Sbjct: 2555 PDLEWYFQ--DKPIPKSEKYSIKNDGDHHMLIVNNCEKGDQGVYKCIASNREGKDITQGR 2612 Query: 287 LTVY---------DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337 L + +PP ++ G VA+FT ATG PEP + W + +FP Sbjct: 2613 LDIVNEIKKHSRSEPPVFLKKIGDCDIYEGMVAKFTACATGYPEPEVEWFKNDQK--LFP 2670 Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397 D++ +G+ LTI + + D C N G +L S D + Sbjct: 2671 S---DRFLIDIEPNGLLRLTIKNVTEYDV-GRYSCRIFNPYGDDICHAELFYDSLDSQQK 2726 Query: 398 PI 399 P+ Sbjct: 2727 PL 2728 Score = 96.7 bits (230), Expect = 3e-18 Identities = 123/474 (25%), Positives = 190/474 (40%), Gaps = 52/474 (10%) Query: 37 GSPSPAIRWYKGG--VLVVSDTHRSILPAGGLFFLRATHGRVH-SDAGVYWCEATNSYGT 93 G P P +++YK +L +D + I L F V +DAG Y C+ATN +G Sbjct: 1059 GDPKPRVKFYKDEKEILETNDRIQIIRDKDYLGFYELVIADVQKTDAGTYSCKATNKHGE 1118 Query: 94 ARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDG 153 A +A E+ P S Q + P G +P WK+NG+ FD Sbjct: 1119 ANCEA----IATTVED--KNPFGALSGQ--------ILPAGE-KPVFQWKRNGEE--FDP 1161 Query: 154 DSRMHLVDGGN-----LVIQDARQTDAGRYQCIARNAAG--------TRESAIATLKIHI 200 + R ++ G + LV Q + DAG Y C+A+ + G + + AI TL Sbjct: 1162 EERFKVLFGEDEDSLALVFQHVKPEDAGIYTCVAQTSTGNISCSAELSVQGAIQTLNREP 1221 Query: 201 -KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---S 256 KP L+ + A G S + + G P P V W+ + + +D S Sbjct: 1222 EKPTLVIEHREANASIGGSAILELQCKGFPKPAVQWKHDGEVIQVDDRHKFMYEDEESMS 1281 Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316 L + NV D G Y+ EA N +G +S L V PP I + +G + Sbjct: 1282 LVIKNVDTVDAGVYTIEAINELGQDESSINLVVKAPPKIK-KITDITCSAGETIKMEIEV 1340 Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV--TVLTINDTDKNDSRNTIVCSA 374 G P+PT+ V N + S K ++++ + V+ + + + + N + A Sbjct: 1341 EGFPQPTV--QVTNNGKDV-TAESNVKISSSSIGKSLEKVVVEVKEIKLSQAGNYSI-KA 1396 Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF- 433 N + TV S P I+ N S K PE + WY Sbjct: 1397 TNDLSQTSEYWSCTVKS----KPVIVKNFESEYIHGEKENVQMTVRIDAYPEAKLTWYHD 1452 Query: 434 EGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 E E I + + V++DG TL + + D+G YT A++ HG S LL+ Sbjct: 1453 ETEIKITDSKYTVSSDGNAYTLKITGATRVDAGKYTVKATNEHGSATSSTQLLI 1506 Score = 83.4 bits (197), Expect = 3e-14 Identities = 118/549 (21%), Positives = 213/549 (38%), Gaps = 67/549 (12%) Query: 31 LNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89 + R P + WY + ++D+ ++ G + L+ T G DAG Y +ATN Sbjct: 1435 MTVRIDAYPEAKLTWYHDETEIKITDSKYTVSSDGNAYTLKIT-GATRVDAGKYTVKATN 1493 Query: 90 SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149 +G+A S +T + EF + ++ A+GD+ V + P P+ W +G + Sbjct: 1494 EHGSATS--STQLLIKCAPEFTHKLKNITVAEGDSNVELVVGVDAYPRPHAKWYIDGIEI 1551 Query: 150 LFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG 207 + H+ +G + L++ G Y C N G E + ++ KP + G Sbjct: 1552 DEKRNDFRHVEEGNDFKLIMNQVATNMQGNYTCKIMNDYGKLEDN-CVVTVNCKPKVKRG 1610 Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA-- 265 ++V Q G S T + V +P + W + G R+K+ D + R++N L Sbjct: 1611 LKNVEVQEGKSFTLEVEVYSEPEAKIKWFKD-GHEIYEDARIKISRD-TQRIENYYLTLN 1668 Query: 266 -----DEGEYSCEAENSVGAVSASGYLTVYDPPSINLS-------------------PNS 301 D G Y +A N +G +++ + V +++L P Sbjct: 1669 LARTEDAGTYEMKATNFIGETTSTCKVAVLTSEALSLEQTVTKTLIATTEEPEEGAVPEI 1728 Query: 302 VNVE-------SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354 V+V+ ++ ATG P+P W +G ++ DK+ A V Sbjct: 1729 VHVDVFQQHSYESVPLKYEVIATGIPKPEAIWYHDGK------PITPDKHTAITVDGDHY 1782 Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK-- 412 L + D D+ V N G +G+L+++ + PI+T GP + + + Sbjct: 1783 KLEVQSLDLVDAGEYKVV-VQNKVGEKSHQGELSLSGIAEYRKPILTQGPGLKDIKVNKG 1841 Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG------------TLVLKDLDKS 460 P P P I +G+ +++ + + D TL + + + Sbjct: 1842 DKVCEPVVFTADPAPEIVLLKDGQPVVETNNVKLKVDKKDAENGLVQYTCTLNILEAEIK 1901 Query: 461 DSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSV 520 DSG Y +++G+ V SG +D P I D LPG + Sbjct: 1902 DSGRYELKVKNKYGELVTSG--WIDVLAKPEISGLN--DTKCLPGDTICFEALVQANPKP 1957 Query: 521 TLSWSQNNK 529 +SW++ N+ Sbjct: 1958 KVSWTRGNE 1966 Score = 79.8 bits (188), Expect = 4e-13 Identities = 106/422 (25%), Positives = 168/422 (39%), Gaps = 41/422 (9%) Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPE---------SKQSAQGDTVVLEC 129 DAG+Y C A S G S +A L V + EPE ++ G + +LE Sbjct: 1187 DAGIYTCVAQTSTGNI-SCSAELSVQGAIQTLNREPEKPTLVIEHREANASIGGSAILE- 1244 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD--GGNLVIQDARQTDAGRYQCIARNAAG 187 L +G P+P V WK +G+ + D + D +LVI++ DAG Y A N G Sbjct: 1245 LQCKGFPKPAVQWKHDGEVIQVDDRHKFMYEDEESMSLVIKNVDTVDAGVYTIEAINELG 1304 Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGGGN 243 ES+I L + P I D+ G ++ + V G P P V + N Sbjct: 1305 QDESSI-NLVVKAPP-KIKKITDITCSAGETIKMEIEVEGFPQPTVQVTNNGKDVTAESN 1362 Query: 244 MPLGRV---KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLS 298 + + K L+ + + + L+ G YS +A N + S TV P I N Sbjct: 1363 VKISSSSIGKSLEKVVVEVKEIKLSQAGNYSIKATNDLSQTSEYWSCTVKSKPVIVKNFE 1422 Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358 ++ E NV + T PE + W + I + KY ++ + T+ Sbjct: 1423 SEYIHGEKENV-QMTVRIDAYPEAKLTWYHDETEIKI----TDSKYTVSSDGNAYTLKIT 1477 Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418 T + + T+ A N GS+ +L + + P T+ N T+ V Sbjct: 1478 GATRVDAGKYTV--KATNEHGSATSSTQLLI-----KCAPEFTHKLKNITVAEGDSNVEL 1530 Query: 419 CTAI-CTPEPIIAWYFEGEALIQ--NHRRNVT--NDGTLVLKDLDKSDSGTYTCVASSRH 473 + P P WY +G + + N R+V ND L++ + + G YTC + + Sbjct: 1531 VVGVDAYPRPHAKWYIDGIEIDEKRNDFRHVEEGNDFKLIMNQVATNMQGNYTCKIMNDY 1590 Query: 474 GK 475 GK Sbjct: 1591 GK 1592 Score = 73.7 bits (173), Expect = 3e-11 Identities = 112/476 (23%), Positives = 187/476 (39%), Gaps = 43/476 (9%) Query: 35 AGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTA 94 A G P P WY G + D H +I G + L + DAG Y N G Sbjct: 1750 ATGIPKPEAIWYHDGKPITPDKHTAITVDGDHYKLEVQSLDL-VDAGEYKVVVQNKVGE- 1807 Query: 95 RSRNATLH---VAVLREEFRLE-PESKQSA--QGDTVVLECLPPRGSPEPNVYWKKNGQT 148 +S L +A R+ + P K +GD V E + P P + K+GQ Sbjct: 1808 KSHQGELSLSGIAEYRKPILTQGPGLKDIKVNKGDKVC-EPVVFTADPAPEIVLLKDGQP 1866 Query: 149 LLFDGDSRMHL--VDGGNLVIQ--------DARQTDAGRYQCIARNAAGTRESAIATLKI 198 ++ + ++ + D N ++Q +A D+GRY+ +N G ++ + + Sbjct: 1867 VVETNNVKLKVDKKDAENGLVQYTCTLNILEAEIKDSGRYELKVKNKYGELVTS-GWIDV 1925 Query: 199 HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGGGNMPLGRVKVLDD 254 KP I+G D G ++ F+ V +P P V W R N + D Sbjct: 1926 LAKPE-ISGLNDTKCLPGDTICFEALVQANPKPKVSWTRGNENLCNHENCEVIADVDADK 1984 Query: 255 GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV-YDPPSINLSPNSVNVESGNVARFT 313 L +V ++G+Y+ A NS G + L V + P+ + P S ++ Sbjct: 1985 YRLVFQSVSPCEDGKYTITATNSEGRAAVDFNLAVLVEKPTFIVQPESQSIHDYRPVSTK 2044 Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMS---RDKYHATA-VFDGV----TVLTINDTDKND 365 G P PT+ W + ++ I + ++ +DK +A G +VL I +ND Sbjct: 2045 VLVHGVPLPTIEW-FKDDKPINYEAINKPGKDKLYAKEDTKKGTDQIESVLDIKSFREND 2103 Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425 C A N G + KL + S P + + + V C +P Sbjct: 2104 V-GAYTCVATNEIGVTKAPFKLAMLS---LAPSFVKKLDNALDVLQGEPLVLECCVDGSP 2159 Query: 426 EPIIAWYFEGEALIQNHRRNV-TNDGTLVLKDLDK---SDSGTYTCVASSRHGKYV 477 P + W +G+ + + + TN LV +++ +DSG Y + S+ HG+ V Sbjct: 2160 LPTVQWLKDGDEVKPSESIKISTNPDGLVKLEINSCQPNDSGAYKLIISNPHGEKV 2215 Score = 73.7 bits (173), Expect = 3e-11 Identities = 101/477 (21%), Positives = 178/477 (37%), Gaps = 43/477 (9%) Query: 38 SPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS-DAGVYWCEATNSYGTARS 96 +P P + W +G + + + ++ R V + G Y ATNS G A + Sbjct: 1954 NPKPKVSWTRGNENLCNHENCEVIADVDADKYRLVFQSVSPCEDGKYTITATNSEGRA-A 2012 Query: 97 RNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFD---- 152 + L V V + F ++PES QS V + G P P + W K+ + + ++ Sbjct: 2013 VDFNLAVLVEKPTFIVQPES-QSIHDYRPVSTKVLVHGVPLPTIEWFKDDKPINYEAINK 2071 Query: 153 -GDSRMHLVDGGN---------LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKP 202 G +++ + L I+ R+ D G Y C+A N G ++ + + P Sbjct: 2072 PGKDKLYAKEDTKKGTDQIESVLDIKSFRENDVGAYTCVATNEIGVTKAPFKLAMLSLAP 2131 Query: 203 YLITGPEDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL--DDG--SL 257 + ++ + G + +C V G PLP V W + G P +K+ DG L Sbjct: 2132 SFVKKLDNALDVLQGEPLVLECCVDGSPLPTVQWLKD-GDEVKPSESIKISTNPDGLVKL 2190 Query: 258 RLDNVILADEGEYSCEAENSVG---AVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314 +++ D G Y N G A+ A P S V G + Sbjct: 2191 EINSCQPNDSGAYKLIISNPHGEKVALCAVAVKPEEMQPKFLKPITSQTVVVGEPLKLEA 2250 Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374 TG P P + W +G ++ P + ++ +G L I+ D+ C Sbjct: 2251 QVTGFPAPEVKWYKDG--MLLRPSPEINFINSP---NGQIGLIIDAAQPLDA-GVYKCLI 2304 Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPI--ITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432 N G K+ + + +P + + + S + P+K + P+P + W+ Sbjct: 2305 ANKGGEIEGVSKVEIVPKESKPVFVAELQDASSIEGFPVK----MDIKVVGNPKPKLQWF 2360 Query: 433 FEGEALIQNHR-----RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 G + + N N +L+++ DSG Y +A + G L V Sbjct: 2361 HNGHEIKPDASHIAIVENPDNSSSLIIEKTAPGDSGLYEVIAQNPEGSTASKAKLYV 2417 Score = 68.5 bits (160), Expect = 1e-09 Identities = 97/484 (20%), Positives = 180/484 (37%), Gaps = 35/484 (7%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPAGGLFF 68 E P ++ + + + A L + G P PA++W + G V+ V D H+ + Sbjct: 1222 EKPTLVIEHREANASIGGSAILELQCKGFPKPAVQWKHDGEVIQVDDRHKFMYEDEESMS 1281 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128 L + DAGVY EA N G S ++++ V + + G+T+ +E Sbjct: 1282 LVIKNVDT-VDAGVYTIEAINELGQDES---SINLVVKAPPKIKKITDITCSAGETIKME 1337 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN------LVIQDARQTDAGRYQCIA 182 + G P+P V NG+ + + + ++ G + +++ + + AG Y A Sbjct: 1338 -IEVEGFPQPTVQVTNNGKDVTAESNVKISSSSIGKSLEKVVVEVKEIKLSQAGNYSIKA 1396 Query: 183 RNAAGTRESAIATLKIHIKPYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241 N ++ S + + KP ++ E + + +V R+ P + W Sbjct: 1397 TNDL-SQTSEYWSCTVKSKPVIVKNFESEYIHGEKENVQMTVRIDAYPEAKLTWYHDETE 1455 Query: 242 GNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298 + + V DG +L++ D G+Y+ +A N G+ ++S L + P Sbjct: 1456 IKITDSKYTVSSDGNAYTLKITGATRVDAGKYTVKATNEHGSATSSTQLLIKCAPEFTHK 1515 Query: 299 PNSVNVESGNV-ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 ++ V G+ P P W ++G I D H V +G Sbjct: 1516 LKNITVAEGDSNVELVVGVDAYPRPHAKWYIDG---IEIDEKRNDFRH---VEEGNDFKL 1569 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417 I + + + C +N G +TV P + G N + Sbjct: 1570 IMNQVATNMQGNYTCKIMNDYGKLEDNCVVTVNC-----KPKVKRGLKNVEVQEGKSFTL 1624 Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT------LVLKDLDKSDSGTYTCVASS 471 PE I W+ +G + ++ R ++ D L L D+GTY A++ Sbjct: 1625 EVEVYSEPEAKIKWFKDGHEIYEDARIKISRDTQRIENYYLTLNLARTEDAGTYEMKATN 1684 Query: 472 RHGK 475 G+ Sbjct: 1685 FIGE 1688 Score = 51.6 bits (118), Expect = 1e-04 Identities = 54/220 (24%), Positives = 87/220 (39%), Gaps = 32/220 (14%) Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT--NDGTLVL 454 PP P + + C A+ P+P + W+ L ++ R ++ DG +L Sbjct: 3564 PPFFREKPQTIAITENQPSHIHCFAVGDPKPCVQWFKNDMVLTESKRIKISVDEDGRSIL 3623 Query: 455 K--DLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPIT 512 + D G Y VA ++ G+ V ++V ++LP P P Sbjct: 3624 RFEPALHFDVGVYKVVARNKVGQTVARCRIVV----------------ATLPDAPDSPEI 3667 Query: 513 HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHY 572 + T + L W Q G S++L Y ++ LS N W +A + Y Sbjct: 3668 SANSGTEILLRWKQPRDDGHSTVLCYSLQY----KLS------NCDAWTTVADNIDHEFY 3717 Query: 573 VVKSLIPGITYMFIVRTENSHGLSGPS-PVSDSVTVGDDS 611 ++ L P Y F + ++N G S PVS S TVG D+ Sbjct: 3718 LLHDLQPNTNYQFRLASKNRIGWSEMGIPVSAS-TVGGDA 3756 Score = 51.2 bits (117), Expect = 2e-04 Identities = 90/403 (22%), Positives = 159/403 (39%), Gaps = 51/403 (12%) Query: 165 LVIQDARQTDAGRYQCIARNAAGTR----ESAIATL------KIHIKPYLITGPEDVVAQ 214 L I++ +TDAG Y A++A+ T + A+ K + +P + +D Sbjct: 987 LDIKNCSETDAGTYTIRAQSASETTTVSAQLAVGQAPGHDETKTNTEPAFLVSLKDAEMI 1046 Query: 215 TGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS------LRLDNVILADEG 268 + F ++ GDP P V + + R++++ D L + +V D G Sbjct: 1047 ENTLFRFMVKIIGDPKPRVKFYKDEKEILETNDRIQIIRDKDYLGFYELVIADVQKTDAG 1106 Query: 269 EYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328 YSC+A N G + T + + + + + +G F G + Sbjct: 1107 TYSCKATNKHGEANCEAIATTVEDKNPFGALSGQILPAGEKPVFQWKRNGEE-----FDP 1161 Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVTV--LTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386 E ++F D+ VF V I S I CSA V+G Sbjct: 1162 EERFKVLF---GEDEDSLALVFQHVKPEDAGIYTCVAQTSTGNISCSA-----ELSVQGA 1213 Query: 387 L-TVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN 445 + T+ + ++P +I + +N ++ ++ C P+P + W +GE + + R Sbjct: 1214 IQTLNREPEKPTLVIEHREANASIGGSAILELQCKGF--PKPAVQWKHDGEVIQVDDRHK 1271 Query: 446 VTNDG----TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVS 501 + +LV+K++D D+G YT A + G+ S L+V +P P I + D++ Sbjct: 1272 FMYEDEESMSLVIKNVDTVDAGVYTIEAINELGQDESSINLVVKAP--PKIK--KITDIT 1327 Query: 502 SLPGPPTK---------PITHNVTDTSVTLSWSQNNKIGSSSI 535 G K T VT+ ++ N KI SSSI Sbjct: 1328 CSAGETIKMEIEVEGFPQPTVQVTNNGKDVTAESNVKISSSSI 1370 Score = 50.8 bits (116), Expect = 2e-04 Identities = 37/121 (30%), Positives = 57/121 (47%), Gaps = 8/121 (6%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLF 67 G P+ E+P + + +QP+ ++C A G P P ++W+K VL S + + G Sbjct: 3562 GYPPFFREKPQTIAITENQPSHIHCFAVGDPKPCVQWFKNDMVLTESKRIKISVDEDGRS 3621 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ-SAQGDTVV 126 LR +H D GVY A N G +R + VA L + P+S + SA T + Sbjct: 3622 ILR-FEPALHFDVGVYKVVARNKVGQTVAR-CRIVVATLPD----APDSPEISANSGTEI 3675 Query: 127 L 127 L Sbjct: 3676 L 3676 Score = 48.8 bits (111), Expect = 9e-04 Identities = 116/527 (22%), Positives = 188/527 (35%), Gaps = 61/527 (11%) Query: 11 APYIIEQPLDVTVARHQP-ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 AP + ++TVA L P P +WY G+ + + G F Sbjct: 1509 APEFTHKLKNITVAEGDSNVELVVGVDAYPRPHAKWYIDGIEIDEKRNDFRHVEEGNDFK 1568 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 + + G Y C+ N YG N + V + + + ++ + +G + LE Sbjct: 1569 LIMNQVATNMQGNYTCKIMNDYGKLED-NCVVTVNC-KPKVKRGLKNVEVQEGKSFTLE- 1625 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRM----HLVDGGNLVIQDARQTDAGRYQCIARNA 185 + PE + W K+G + D ++ ++ L + AR DAG Y+ A N Sbjct: 1626 VEVYSEPEAKIKWFKDGHEIYEDARIKISRDTQRIENYYLTLNLARTEDAGTYEMKATNF 1685 Query: 186 AGTRES----AIAT-----LKIHIKPYLITGPE-------------DVVAQTG-SSVTFQ 222 G S A+ T L+ + LI E DV Q SV + Sbjct: 1686 IGETTSTCKVAVLTSEALSLEQTVTKTLIATTEEPEEGAVPEIVHVDVFQQHSYESVPLK 1745 Query: 223 CRV--GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENS 277 V G P P+ +W G P + DG L + ++ L D GEY +N Sbjct: 1746 YEVIATGIPKPEAIWYHD-GKPITPDKHTAITVDGDHYKLEVQSLDLVDAGEYKVVVQNK 1804 Query: 278 VGAVSASGYLTV-----YDPPSINLSP--NSVNVESGNVARFTCTATGRPEPTMFWSVEG 330 VG S G L++ Y P + P + V G+ T P P + +G Sbjct: 1805 VGEKSHQGELSLSGIAEYRKPILTQGPGLKDIKVNKGDKVCEPVVFTADPAPEIVLLKDG 1864 Query: 331 NRTIIFPG--MSRDKYHA-TAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387 + + DK A + L I + + DS N G G + Sbjct: 1865 QPVVETNNVKLKVDKKDAENGLVQYTCTLNILEAEIKDS-GRYELKVKNKYGELVTSGWI 1923 Query: 388 TVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT 447 V + P I+ + LP ++ F P+P ++W E L + V Sbjct: 1924 DVLA-----KPEISGLNDTKCLPGDTIC-FEALVQANPKPKVSWTRGNENLCNHENCEVI 1977 Query: 448 ND-----GTLVLKDLDKSDSGTYTCVASSRHGKYV--WSGALLVDSP 487 D LV + + + G YT A++ G+ ++ A+LV+ P Sbjct: 1978 ADVDADKYRLVFQSVSPCEDGKYTITATNSEGRAAVDFNLAVLVEKP 2024 Score = 41.9 bits (94), Expect = 0.10 Identities = 32/124 (25%), Positives = 53/124 (42%), Gaps = 6/124 (4%) Query: 165 LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR 224 L I D G Y+ +A N G + L+I P + P++ + + + Sbjct: 2942 LFINKMLDRDVGWYEAVATNEHGEARQRVR-LEIAEHPRFLKRPDETFIMARKNGRIEAK 3000 Query: 225 VGGDPLPDVLWRRSAGGGNMPLGRVKVL----DDGSLRLDNVILADEGEYSCEAENSVGA 280 + G PLP+V W + + R+K+ D L + + I+ D G YS A N G+ Sbjct: 3001 LVGIPLPEVHWFKD-WKPIVDSSRIKISSYDPDIYVLSIHDSIIKDGGLYSISARNIAGS 3059 Query: 281 VSAS 284 +S S Sbjct: 3060 ISTS 3063 Score = 38.7 bits (86), Expect = 0.96 Identities = 20/101 (19%), Positives = 44/101 (43%), Gaps = 1/101 (0%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P +++P + + + + + G P P + W+K +V + I ++ Sbjct: 2976 EHPRFLKRPDETFIMARKNGRIEAKLVGIPLPEVHWFKDWKPIVDSSRIKISSYDPDIYV 3035 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEF 110 + H + D G+Y A N G+ S + T+H+ +++ Sbjct: 3036 LSIHDSIIKDGGLYSISARNIAGSI-STSVTVHIEENEDQY 3075 Score = 36.7 bits (81), Expect = 3.9 Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 8/125 (6%) Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138 D G Y ATN +G AR R L +A + E+ A+ + + L G P P Sbjct: 2951 DVGWYEAVATNEHGEARQR-VRLEIAEHPRFLKRPDETFIMARKNGRIEAKLV--GIPLP 3007 Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLV--IQDARQTDAGRYQCIARNAAGTRESAIATL 196 V+W K+ + ++ ++ D V I D+ D G Y ARN AG+ +++ Sbjct: 3008 EVHWFKDWKPIVDSSRIKISSYDPDIYVLSIHDSIIKDGGLYSISARNIAGSISTSVT-- 3065 Query: 197 KIHIK 201 +HI+ Sbjct: 3066 -VHIE 3069 >UniRef50_Q8WZ75 Cluster: Roundabout homolog 4 precursor; n=22; Theria|Rep: Roundabout homolog 4 precursor - Homo sapiens (Human) Length = 1007 Score = 147 bits (355), Expect = 2e-33 Identities = 86/212 (40%), Positives = 115/212 (54%), Gaps = 14/212 (6%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSDTHRSILPAGGLFF 68 P I+ P D PA ++C+A G P P IRW G +V D H +LP G L Sbjct: 32 PQILVHPQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPPDPHH-LLPDGTLLL 90 Query: 69 LRA-THGRVH------SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121 L+ G H +D GVY CEA+N GTA SR A L VAVLRE+F+++P + Sbjct: 91 LQPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARLSVAVLREDFQIQPRDMVAVV 150 Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181 G+ LEC PP G PEP V W K+G+ L H V GG+L++ A ++D G Y C+ Sbjct: 151 GEQFTLECGPPWGHPEPTVSWWKDGKPLAL--QPGRHTVSGGSLLMARAEKSDEGTYMCV 208 Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVA 213 A N+AG RES A + I +P T P +++A Sbjct: 209 ATNSAGHRESRAARVSIQ-EPQDYTEPVELLA 239 Score = 60.9 bits (141), Expect = 2e-07 Identities = 50/196 (25%), Positives = 84/196 (42%), Gaps = 25/196 (12%) Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 PP I + P + AR +C A+G+P PT+ W + G + P D +H D Sbjct: 31 PPQILVHPQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPP---DPHHLLP--D 85 Query: 352 GVTVLTINDTDKNDSRN---------TIVCSAVNYAGSSFVRG---KLTVTSDDDRPPPI 399 G T+L + + + + C A N G++ RG + V +D + P Sbjct: 86 G-TLLLLQPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARLSVAVLREDFQIQP- 143 Query: 400 ITNGPSNQTLPIKSMAVFPCTAICT-PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLD 458 + + C PEP ++W+ +G+ L R+ + G+L++ + Sbjct: 144 -----RDMVAVVGEQFTLECGPPWGHPEPTVSWWKDGKPLALQPGRHTVSGGSLLMARAE 198 Query: 459 KSDSGTYTCVASSRHG 474 KSD GTY CVA++ G Sbjct: 199 KSDEGTYMCVATNSAG 214 Score = 54.0 bits (124), Expect = 2e-05 Identities = 46/134 (34%), Positives = 61/134 (45%), Gaps = 8/134 (5%) Query: 693 EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKW 752 E+ L YEF + P + G SN + + + VP PP + + N T V + W Sbjct: 309 ELGGLHWGQDYEFKVRPSSGRARGPDSNVLLLRLPEKVPSAPPQEVTLKPGNGT-VFVSW 367 Query: 753 SPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN-TTVHQATSLIMTNLTSGVSYSVQIA 811 PP + NGII GY V W N S+ N T V + T L + G SY VQ+A Sbjct: 368 VPPPAENHNGIIRGYQV---W--SLGNTSLPPANWTVVGEQTQLEIATHMPG-SYCVQVA 421 Query: 812 AETIIGLGPFSQKV 825 A T G G S+ V Sbjct: 422 AVTGAGAGEPSRPV 435 Score = 51.2 bits (117), Expect = 2e-04 Identities = 55/214 (25%), Positives = 85/214 (39%), Gaps = 26/214 (12%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM-PLGRVKVLDDGSLRL- 259 P ++ P+D + Q C+ G P P + W + +M P +L DG+L L Sbjct: 32 PQILVHPQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPPDPHHLLPDGTLLLL 91 Query: 260 ----------DNVILADEGEYSCEAENSVG-AVSASGYLTV-YDPPSINLSPNSVNVESG 307 + D G Y+CEA N +G AVS L+V + P + G Sbjct: 92 QPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARLSVAVLREDFQIQPRDMVAVVG 151 Query: 308 NVARFTC-TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 C G PEPT+ W +G + PG H + G ++L +K+D Sbjct: 152 EQFTLECGPPWGHPEPTVSWWKDGKPLALQPGR-----HTVS---GGSLLMAR-AEKSD- 201 Query: 367 RNTIVCSAVNYAGSSFVR-GKLTVTSDDDRPPPI 399 T +C A N AG R ++++ D P+ Sbjct: 202 EGTYMCVATNSAGHRESRAARVSIQEPQDYTEPV 235 Score = 39.5 bits (88), Expect = 0.55 Identities = 33/103 (32%), Positives = 43/103 (41%), Gaps = 14/103 (13%) Query: 394 DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL--IQNHRRNVTNDGT 451 D PP I+ + P +Q A C A P P I W G+ L + ++ DGT Sbjct: 29 DSPPQILVH-PQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPPDPHHLLPDGT 87 Query: 452 LVLKDLD-----------KSDSGTYTCVASSRHGKYVWSGALL 483 L+L +D G YTC AS+R G V GA L Sbjct: 88 LLLLQPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARL 130 >UniRef50_Q9NR99 Cluster: Matrix-remodeling-associated protein 5 precursor; n=12; Amniota|Rep: Matrix-remodeling-associated protein 5 precursor - Homo sapiens (Human) Length = 2828 Score = 147 bits (355), Expect = 2e-33 Identities = 136/499 (27%), Positives = 208/499 (41%), Gaps = 48/499 (9%) Query: 9 GEAPYII-EQPLDVTVARHQPATLNCRAGGSPSPAIRWYK--GGVLVVSDTH--RSILPA 63 GE P I+ + P V+V C A G P P + W K G L+ +T R + Sbjct: 1850 GEKPQILTKSPQTVSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVLK 1909 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-G 122 G +R + D G Y C A+N +G R L V V + + + G Sbjct: 1910 NGTLVIRKVQVQ---DRGQYMCTASNLHGLDRMV-VLLSVTVQQPQILASHYQDVTVYLG 1965 Query: 123 DTVVLECLPPRGSPEPNVYW----KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY 178 DT+ +ECL +G+P P + W ++ QT+ +SR+ L + L I++A +D G Y Sbjct: 1966 DTIAMECLA-KGTPAPQISWIFPDRRVWQTVS-PVESRITLHENRTLSIKEASFSDRGVY 2023 Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 +C+A NAAG AI + P + E++ G S+ C PLP V W Sbjct: 2024 KCVASNAAGADSLAIRLHVAALPPVIHQEKLENISLPPGLSIHIHCTAKAAPLPSVRWVL 2083 Query: 238 SAGGGNMPL----GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293 G P G + V +G+L + N+ D G Y C A N VG+ + L V Sbjct: 2084 GDGTQIRPSQFLHGNLFVFPNGTLYIRNLAPKDSGRYECVAANLVGSARRTVQLNVQRAA 2143 Query: 294 S----INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI--IFPGMSRDKYHAT 347 + SP +V G + C+A+G P P + W + R I +F SR K A Sbjct: 2144 ANARITGTSPRRTDVRYGGTLKLDCSASGDPWPRILWRLPSKRMIDALFSFDSRIKVFAN 2203 Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407 + V ++ D D D +C A N G +V K+ V +P I ++ Sbjct: 2204 GT---LVVKSVTDKDAGD----YLCVARNKVGDDYVVLKVDVVM---KPAKIEHKEENDH 2253 Query: 408 TLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN-----------VTNDGTLVLKD 456 + C A P P I+W +L+ + ++ V N+GTL + Sbjct: 2254 KVFYGGDLKVDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNE 2313 Query: 457 LDKSDSGTYTCVASSRHGK 475 + + G YTC A ++ GK Sbjct: 2314 VGMREEGDYTCFAENQVGK 2332 Score = 138 bits (334), Expect = 9e-31 Identities = 136/480 (28%), Positives = 206/480 (42%), Gaps = 55/480 (11%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDT---HRS--ILPAGGLFFLRATHGRVHSDAGVYWC 85 ++C A +P P++RW G + + H + + P G L+ D+G Y C Sbjct: 2067 IHCTAKAAPLPSVRWVLGDGTQIRPSQFLHGNLFVFPNGTLYI----RNLAPKDSGRYEC 2122 Query: 86 EATNSYGTARSRNATLHVAVLREEFRL---EPESKQSAQGDTVVLECLPPRGSPEPNVYW 142 A N G+AR R L+V R+ P G T+ L+C G P P + W Sbjct: 2123 VAANLVGSAR-RTVQLNVQRAAANARITGTSPRRTDVRYGGTLKLDC-SASGDPWPRILW 2180 Query: 143 KKNGQTL---LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199 + + + LF DSR+ + G LV++ DAG Y C+ARN G + + + + Sbjct: 2181 RLPSKRMIDALFSFDSRIKVFANGTLVVKSVTDKDAGDYLCVARNKVGD-DYVVLKVDVV 2239 Query: 200 IKPYLITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-------GNMPLGRVK 250 +KP I E D G + C G P P++ W G + GR K Sbjct: 2240 MKPAKIEHKEENDHKVFYGGDLKVDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTK 2299 Query: 251 ---VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNVE 305 V ++G+L + V + +EG+Y+C AEN VG + V P+ N + +V V Sbjct: 2300 RYVVFNNGTLYFNEVGMREEGDYTCFAENQVGKDEMRVRVKVVTAPATIRNKTYLAVQVP 2359 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365 G+V C A G P P + W N+ I S +KY ++ T+L I ++D Sbjct: 2360 YGDVVTVACEAKGEPMPKVTWLSPTNKVI---PTSSEKYQ---IYQDGTLL-IQKAQRSD 2412 Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA------VFPC 419 S N C N AG + TV + PP I NG N ++ +A + C Sbjct: 2413 SGN-YTCLVRNSAGED----RKTVWIHVNVQPPKI-NGNPNPITTVREIAAGGSRKLIDC 2466 Query: 420 TAICTPEPIIAWYF-EGEAL---IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 A P P + W F EG L +R V +G+L ++ L KSDS C+A + G+ Sbjct: 2467 KAEGIPTPRVLWAFPEGVVLPAPYYGNRITVHGNGSLDIRSLRKSDSVQLVCMARNEGGE 2526 Score = 109 bits (262), Expect = 5e-22 Identities = 127/489 (25%), Positives = 206/489 (42%), Gaps = 58/489 (11%) Query: 31 LNCRAGGSPSPAIRW-YKGGVLVVS---------DTHRSILPAGGLFFLRATHGRVHSDA 80 ++C A G P+P I W G LV S T R ++ G + R D Sbjct: 2263 VDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNEVGMREEGD- 2321 Query: 81 GVYWCEATNSYGTARSRNATLHV---AVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137 Y C A N G R V A +R + L + Q GD V + C +G P Sbjct: 2322 --YTCFAENQVGKDEMRVRVKVVTAPATIRNKTYL---AVQVPYGDVVTVAC-EAKGEPM 2375 Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197 P V W ++ + + G L+IQ A+++D+G Y C+ RN+AG + + Sbjct: 2376 PKVTWLSPTNKVIPTSSEKYQIYQDGTLLIQKAQRSDSGNYTCLVRNSAGEDRKTV-WIH 2434 Query: 198 IHIKPYLITG-PEDV-----VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL----G 247 ++++P I G P + +A GS C+ G P P VLW G +P Sbjct: 2435 VNVQPPKINGNPNPITTVREIAAGGSRKLIDCKAEGIPTPRVLW-AFPEGVVLPAPYYGN 2493 Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP--PSINLSPNS--VN 303 R+ V +GSL + ++ +D + C A N G LTV +P I P S + Sbjct: 2494 RITVHGNGSLDIRSLRKSDSVQLVCMARNEGGEARLILQLTVLEPMEKPIFHDPISEKIT 2553 Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363 +G+ C+A G P P++ W V N T + G +++ A DG +L I+ Sbjct: 2554 AMAGHTISLNCSAAGTPTPSLVW-VLPNGTDLQSGQQLQRFYHKA--DG--MLHISGLSS 2608 Query: 364 NDSRNTIVCSAVNYAGSS--FVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421 D+ C A N AG + V K+ + + ++ + + + +TL + PCT Sbjct: 2609 VDA-GAYRCVARNAAGHTERLVSLKVGLKPEANKQYHNLVSIINGETLKL------PCTP 2661 Query: 422 ICTPEPIIAW------YFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 + +W + EG + R ++ ++GTL +++ D GTY C + +G Sbjct: 2662 PGAGQGRFSWTLPNGMHLEGPQTL--GRVSLLDNGTLTVREASVFDRGTYVCRMETEYGP 2719 Query: 476 YVWSGALLV 484 V S ++V Sbjct: 2720 SVTSIPVIV 2728 Score = 104 bits (249), Expect = 2e-20 Identities = 102/387 (26%), Positives = 164/387 (42%), Gaps = 22/387 (5%) Query: 10 EAPYIIEQPLDVTVARHQPA-----TLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPA 63 + P I P +T R A ++C+A G P+P + W + GV++ + + + + Sbjct: 2438 QPPKINGNPNPITTVREIAAGGSRKLIDCKAEGIPTPRVLWAFPEGVVLPAPYYGNRITV 2497 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ--SAQ 121 G L R SD+ C A N G AR + + + +P S++ + Sbjct: 2498 HGNGSLDIRSLR-KSDSVQLVCMARNEGGEARLILQLTVLEPMEKPIFHDPISEKITAMA 2556 Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS--RMHLVDGGNLVIQDARQTDAGRYQ 179 G T+ L C G+P P++ W T L G R + G L I DAG Y+ Sbjct: 2557 GHTISLNC-SAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKADGMLHISGLSSVDAGAYR 2615 Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQ-TGSSVTFQCRVGGDPLPDVLWRRS 238 C+ARNAAG E ++ LK+ +KP ++V+ G ++ C G W Sbjct: 2616 CVARNAAGHTERLVS-LKVGLKPEANKQYHNLVSIINGETLKLPCTPPGAGQGRFSWTLP 2674 Query: 239 AG---GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPS 294 G G LGRV +LD+G+L + + D G Y C E G +V++ + + PP Sbjct: 2675 NGMHLEGPQTLGRVSLLDNGTLTVREASVFDRGTYVCRMETEYGPSVTSIPVIVIAYPPR 2734 Query: 295 INLSPNSV-NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353 I P V GN + C A G P+ + W + +++ + G+ + + + Sbjct: 2735 ITSEPTPVIYTRPGNTVKLNCMAMGIPKADITWELP-DKSHLKAGV-QARLYGNRFLHPQ 2792 Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGS 380 LTI + D+ C A N GS Sbjct: 2793 GSLTIQHATQRDA-GFYKCMAKNILGS 2818 Score = 103 bits (246), Expect = 4e-20 Identities = 118/475 (24%), Positives = 184/475 (38%), Gaps = 36/475 (7%) Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRWYK--GGVLVVSDTHRSILPAGGLFFLRATHGRV 76 L V V T+ C A G P P + W V+ S I G L +A Sbjct: 2354 LAVQVPYGDVVTVACEAKGEPMPKVTWLSPTNKVIPTSSEKYQIYQDGTLLIQKAQ---- 2409 Query: 77 HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPE-----SKQSAQGDTVVLECLP 131 SD+G Y C NS G R + +HV V + P + +A G +++C Sbjct: 2410 RSDSGNYTCLVRNSAGEDR-KTVWIHVNVQPPKINGNPNPITTVREIAAGGSRKLIDC-K 2467 Query: 132 PRGSPEPNVYWKKNGQTLL---FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188 G P P V W +L + G +R+ + G+L I+ R++D+ + C+ARN G Sbjct: 2468 AEGIPTPRVLWAFPEGVVLPAPYYG-NRITVHGNGSLDIRSLRKSDSVQLVCMARNEGGE 2526 Query: 189 RESAI-ATLKIHIKPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG---GG 242 + T+ ++ + P E + A G +++ C G P P ++W G Sbjct: 2527 ARLILQLTVLEPMEKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQS 2586 Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS-PNS 301 L R DG L + + D G Y C A N+ G L V P N N Sbjct: 2587 GQQLQRFYHKADGMLHISGLSSVDAGAYRCVARNAAGHTERLVSLKVGLKPEANKQYHNL 2646 Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361 V++ +G + CT G + W++ + P ++ D T LT+ + Sbjct: 2647 VSIINGETLKLPCTPPGAGQGRFSWTLPNGMHLEGP----QTLGRVSLLDNGT-LTVREA 2701 Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR----PPPIITNGPSNQTLPIKSMAV- 416 D R T VC G S + V + R P P+I P N T+ + MA+ Sbjct: 2702 SVFD-RGTYVCRMETEYGPSVTSIPVIVIAYPPRITSEPTPVIYTRPGN-TVKLNCMAMG 2759 Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471 P I P + G R + G+L ++ + D+G Y C+A + Sbjct: 2760 IPKADITWELPDKSHLKAGVQARLYGNRFLHPQGSLTIQHATQRDAGFYKCMAKN 2814 Score = 89.4 bits (212), Expect = 5e-16 Identities = 77/282 (27%), Positives = 118/282 (41%), Gaps = 17/282 (6%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRWY-KGGVLVVS--DTHRSILPAGGLFFLRATHGRVH 77 +T +LNC A G+P+P++ W G + S R A G+ + G Sbjct: 2552 ITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKADGMLHIS---GLSS 2608 Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137 DAG Y C A N+ G R +L V + E + G+T+ L C PP G+ + Sbjct: 2609 VDAGAYRCVARNAAGHTE-RLVSLKVGLKPEANKQYHNLVSIINGETLKLPCTPP-GAGQ 2666 Query: 138 PNVYWK-KNGQTLLFDGD-SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195 W NG L R+ L+D G L +++A D G Y C G ++I Sbjct: 2667 GRFSWTLPNGMHLEGPQTLGRVSLLDNGTLTVREASVFDRGTYVCRMETEYGPSVTSIPV 2726 Query: 196 LKIHIKPYLITGPEDVV-AQTGSSVTFQCRVGGDPLPDVLW------RRSAGGGNMPLGR 248 + I P + + P V+ + G++V C G P D+ W AG G Sbjct: 2727 IVIAYPPRITSEPTPVIYTRPGNTVKLNCMAMGIPKADITWELPDKSHLKAGVQARLYGN 2786 Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290 + GSL + + D G Y C A+N +G+ S + Y+ V+ Sbjct: 2787 RFLHPQGSLTIQHATQRDAGFYKCMAKNILGSDSKTTYIHVF 2828 Score = 53.2 bits (122), Expect = 4e-05 Identities = 51/208 (24%), Positives = 84/208 (40%), Gaps = 13/208 (6%) Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW 142 Y+ + + + T +R A V+ E + +G L C + S P+++W Sbjct: 455 YYTQYSQTISTKDTRQARGRSWVMIEPSGAVQRDQTVLEGGPCQLSC-NVKASESPSIFW 513 Query: 143 K-KNGQTL---LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198 +G L + D DS+ ++ G L I+ +D+G YQCIA+ + + + + Sbjct: 514 VLPDGSILKAPMDDPDSKFSILSSGWLRIKSMEPSDSGLYQCIAQ-VRDEMDRMVYRVLV 572 Query: 199 HIKPYLITGPEDVVA---QTGSSVTFQCRVGGDPLPDVLW---RRSAGGGNMPLGRVKVL 252 P +D V G SVT C P + W R V +L Sbjct: 573 Q-SPSTQPAEKDTVTIGKNPGESVTLPCNALAIPEAHLSWILPNRRIINDLANTSHVYML 631 Query: 253 DDGSLRLDNVILADEGEYSCEAENSVGA 280 +G+L + V ++D G Y C A N GA Sbjct: 632 PNGTLSIPKVQVSDSGYYRCVAVNQQGA 659 Score = 48.4 bits (110), Expect = 0.001 Identities = 49/181 (27%), Positives = 76/181 (41%), Gaps = 23/181 (12%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWY--KGGVLVV----SDTHRSILPAGGLFFLRATH 73 D TV P L+C S SP+I W G +L D+ SIL +G L Sbjct: 488 DQTVLEGGPCQLSCNVKASESPSIFWVLPDGSILKAPMDDPDSKFSILSSGWL----RIK 543 Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-----QGDTVVLE 128 SD+G+Y C A R + VL + +P K + G++V L Sbjct: 544 SMEPSDSGLYQCIA-----QVRDEMDRMVYRVLVQSPSTQPAEKDTVTIGKNPGESVTLP 598 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFD--GDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186 C PE ++ W + ++ D S ++++ G L I + +D+G Y+C+A N Sbjct: 599 C-NALAIPEAHLSWILPNRRIINDLANTSHVYMLPNGTLSIPKVQVSDSGYYRCVAVNQQ 657 Query: 187 G 187 G Sbjct: 658 G 658 Score = 38.7 bits (86), Expect = 0.96 Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 6/62 (9%) Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRNVTN-----DGTLVLKDLDKSDSGTYTCVASSR 472 PC A+ PE ++W +I N N ++ +GTL + + SDSG Y CVA ++ Sbjct: 598 PCNALAIPEAHLSWILPNRRII-NDLANTSHVYMLPNGTLSIPKVQVSDSGYYRCVAVNQ 656 Query: 473 HG 474 G Sbjct: 657 QG 658 >UniRef50_Q4S6A5 Cluster: Chromosome 9 SCAF14729, whole genome shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 9 SCAF14729, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1693 Score = 146 bits (354), Expect = 3e-33 Identities = 139/475 (29%), Positives = 207/475 (43%), Gaps = 46/475 (9%) Query: 4 DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63 + + G+ + +P + V + ATL C A G P+P I W K + H+ + + Sbjct: 482 EVIVEGKPTASVPEP-QMVVVEGRTATLRCHAHGFPAPVITWSKLRS-PLPWRHKVVNSS 539 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123 + + GR D+G Y C A+N G +++ L V L L P++ G+ Sbjct: 540 ----LVLPSVGR--QDSGEYICRASNRMGASQA-TIKLDVETLPYATLL-PDNVAVRAGE 591 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183 + L+CL G+P W + L SR +V+GG+L I A DAG Y+C+A Sbjct: 592 VIRLQCLA-HGTPPLTYTWTRLDGRL----PSRA-VVNGGDLQINLAAADDAGSYKCVAS 645 Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 N+ G+ E IA + + + P+ V GS+V F C G + W + GG Sbjct: 646 NSVGSSE-VIAKVAVRSPLAVRVSPQVEVRAQGSAVEFTCSAAGGLDTTIEWLKE-GGAL 703 Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS--INLSPNS 301 P VK DG LR++++ ++EG Y C A +S G + LT+ P IN+ + Sbjct: 704 PPNHHVK---DGVLRIEDLEQSNEGVYICRASSSFGQAQDTARLTIQALPKVMINVRTSV 760 Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361 V GN F C A G PEPT+ WS G P H + + + + Sbjct: 761 QTVMIGNSVEFECQALGEPEPTVQWSKVGGS---LPA------HIMVKGGMLRIEQVTEV 811 Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421 D R C+A N GS + L V S P I+ P + + + S AV PC A Sbjct: 812 DAGQYR----CTATNDVGSVQSQVVLNVQS-----LPQISALPEKKEVTVGSDAVLPCVA 862 Query: 422 ICTPEPIIAWY-FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 P P I W EGE + + L + + DSGTY C AS++ GK Sbjct: 863 SGYPAPEIRWSKLEGEL----PSKCLQEVNVLTVPRVAHEDSGTYVCTASNKQGK 913 Score = 127 bits (306), Expect = 2e-27 Identities = 109/397 (27%), Positives = 171/397 (43%), Gaps = 34/397 (8%) Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLECLPPRGSPE 137 D+G Y C A + + ++ + V V + PE + +G T L C G P Sbjct: 462 DSGTYVCTARSGDSSTETK---VEVIVEGKPTASVPEPQMVVVEGRTATLRC-HAHGFPA 517 Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197 P + W K L + H V +LV+ + D+G Y C A N G ++ I L Sbjct: 518 PVITWSKLRSPLPW-----RHKVVNSSLVLPSVGRQDSGEYICRASNRMGASQATIK-LD 571 Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257 + PY P++V + G + QC G P W R G +P R V++ G L Sbjct: 572 VETLPYATLLPDNVAVRAGEVIRLQCLAHGTPPLTYTWTRL--DGRLP-SRA-VVNGGDL 627 Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317 +++ D G Y C A NSVG+ + V P ++ +SP G+ FTC+A Sbjct: 628 QINLAAADDAGSYKCVASNSVGSSEVIAKVAVRSPLAVRVSPQVEVRAQGSAVEFTCSAA 687 Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377 G + T+ W EG G +H V DGV L I D ++++ +C A + Sbjct: 688 GGLDTTIEWLKEG-------GALPPNHH---VKDGV--LRIEDLEQSNE-GVYICRASSS 734 Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437 G + +LT+ + P +I S QT+ I + F C A+ PEP + W G + Sbjct: 735 FGQAQDTARLTIQA---LPKVMINVRTSVQTVMIGNSVEFECQALGEPEPTVQWSKVGGS 791 Query: 438 LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 L + G L ++ + + D+G Y C A++ G Sbjct: 792 L---PAHIMVKGGMLRIEQVTEVDAGQYRCTATNDVG 825 Score = 120 bits (290), Expect = 2e-25 Identities = 125/404 (30%), Positives = 169/404 (41%), Gaps = 43/404 (10%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 PY P +V V + L C A G+P W + + S R+++ G L A Sbjct: 576 PYATLLPDNVAVRAGEVIRLQCLAHGTPPLTYTWTRLDGRLPS---RAVVNGGDLQINLA 632 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECL 130 DAG Y C A+NS G S VAV R+ P+ + AQG V C Sbjct: 633 AA----DDAGSYKCVASNSVG---SSEVIAKVAVRSPLAVRVSPQVEVRAQGSAVEFTC- 684 Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190 G + + W K G L H V G L I+D Q++ G Y C A ++ G + Sbjct: 685 SAAGGLDTTIEWLKEGGAL-----PPNHHVKDGVLRIEDLEQSNEGVYICRASSSFGQAQ 739 Query: 191 SAIATLKIHIKPYLITGPEDVV--AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248 A L I P ++ V G+SV F+C+ G+P P V W S GG++P Sbjct: 740 DT-ARLTIQALPKVMINVRTSVQTVMIGNSVEFECQALGEPEPTVQW--SKVGGSLP-AH 795 Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGN 308 + V G LR++ V D G+Y C A N VG+V + L V P I+ P V G+ Sbjct: 796 IMV-KGGMLRIEQVTEVDAGQYRCTATNDVGSVQSQVVLNVQSLPQISALPEKKEVTVGS 854 Query: 309 VARFTCTATGRPEPTMFWS-VEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367 A C A+G P P + WS +EG P + V VLT+ DS Sbjct: 855 DAVLPCVASGYPAPEIRWSKLEGE----LP---------SKCLQEVNVLTVPRVAHEDS- 900 Query: 368 NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP-SNQTLP 410 T VC+A N G +L V +R P P S TLP Sbjct: 901 GTYVCTASNKQGKVEAFTRLQV---HERVMPYFAQEPLSYLTLP 941 Score = 117 bits (282), Expect = 2e-24 Identities = 101/314 (32%), Positives = 140/314 (44%), Gaps = 26/314 (8%) Query: 162 GGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTF 221 G + I AR D+G Y C AR+ + E+ + + + KP +V G + T Sbjct: 450 GWTVTILAARPEDSGTYVCTARSGDSSTETKVEVI-VEGKPTASVPEPQMVVVEGRTATL 508 Query: 222 QCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281 +C G P P + W + +P R KV++ SL L +V D GEY C A N +GA Sbjct: 509 RCHAHGFPAPVITWSKLRSP--LPW-RHKVVNS-SLVLPSVGRQDSGEYICRASNRMGAS 564 Query: 282 SASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341 A+ L V P L P++V V +G V R C A G P T W+ R P Sbjct: 565 QATIKLDVETLPYATLLPDNVAVRAGEVIRLQCLAHGTPPLTYTWTRLDGR---LP---- 617 Query: 342 DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401 + AV +G L IN +D+ + C A N GSS V K+ V R P + Sbjct: 618 ----SRAVVNGGD-LQINLAAADDA-GSYKCVASNSVGSSEVIAKVAV-----RSPLAVR 666 Query: 402 NGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSD 461 P + S F C+A + I W EG AL NH DG L ++DL++S+ Sbjct: 667 VSPQVEVRAQGSAVEFTCSAAGGLDTTIEWLKEGGALPPNHH---VKDGVLRIEDLEQSN 723 Query: 462 SGTYTCVASSRHGK 475 G Y C ASS G+ Sbjct: 724 EGVYICRASSSFGQ 737 Score = 100 bits (239), Expect = 3e-19 Identities = 77/276 (27%), Positives = 124/276 (44%), Gaps = 29/276 (10%) Query: 78 SDAGVYWCEATNSYGTARSRNATL------HVAVLREEFRLEPESKQSAQGDTVVLECLP 131 +D G Y C+A N++G +R + + + + ++ P++ Q +GDT+ + C Sbjct: 25 ADEGEYTCKALNTHGEHVARVSLVVQKSGSGALGSQPQVQVSPQNIQVHEGDTLRMYCRA 84 Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191 GSP P + W KNG L +RM D G L+I D + +D+G Y C+ N+ G+ + Sbjct: 85 T-GSPTPRLSWLKNGG--LLPAQARMDRTDIGTLLIPDVQLSDSGTYMCVGSNSIGSNSA 141 Query: 192 AIATLKIHIK---PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248 + + P + P Q G S+ C G+P P V W R++G + Sbjct: 142 PVKVTVLKADQSFPAVSIQPSTADIQEGQSLELNCVAPGNPPPKVSWWRASGLSS----N 197 Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY-LTV----------YDPPSINL 297 +VL + LR+ + D GEY+C E + G S+ G+ TV P I + Sbjct: 198 HQVLGN-QLRILSATAEDSGEYTCRVEGNHGNPSSGGHQATVSVSVTSSSSRLQSPIIAI 256 Query: 298 SPNSVNVESGNVARFTCTATGRPEPT-MFWSVEGNR 332 P+S V G A F C +P + W V N+ Sbjct: 257 EPHSAVVRVGETATFRCRIYSGAQPVRLEWKVANNQ 292 Score = 86.2 bits (204), Expect = 5e-15 Identities = 70/291 (24%), Positives = 119/291 (40%), Gaps = 33/291 (11%) Query: 159 LVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL-------KIHIKPYLITGPEDV 211 ++ GG L D G Y C A N G + ++ + + +P + P+++ Sbjct: 11 VIRGGVLTFAAVDAADEGEYTCKALNTHGEHVARVSLVVQKSGSGALGSQPQVQVSPQNI 70 Query: 212 VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGSLRLDNVILADEGEY 270 G ++ CR G P P + W ++ GG +P R+ D G+L + +V L+D G Y Sbjct: 71 QVHEGDTLRMYCRATGSPTPRLSWLKN--GGLLPAQARMDRTDIGTLLIPDVQLSDSGTY 128 Query: 271 SCEAENSVGAVSASGYLTVYDP----PSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326 C NS+G+ SA +TV P++++ P++ +++ G C A G P P + W Sbjct: 129 MCVGSNSIGSNSAPVKVTVLKADQSFPAVSIQPSTADIQEGQSLELNCVAPGNPPPKVSW 188 Query: 327 ----SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382 + N ++ G ATA G + N S +G Sbjct: 189 WRASGLSSNHQVL--GNQLRILSATAEDSGEYTCRVEGNHGNPS-----------SGGHQ 235 Query: 383 VRGKLTVTSDDDR-PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAW 431 ++VTS R PII P + + + A F C +P+ + W Sbjct: 236 ATVSVSVTSSSSRLQSPIIAIEPHSAVVRVGETATFRCRIYSGAQPVRLEW 286 Score = 83.8 bits (198), Expect = 3e-14 Identities = 69/233 (29%), Positives = 98/233 (42%), Gaps = 25/233 (10%) Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVG--------AVSASGYLTVYDPPSINLSPNSV 302 V+ G L V ADEGEY+C+A N+ G V SG + P + +SP ++ Sbjct: 11 VIRGGVLTFAAVDAADEGEYTCKALNTHGEHVARVSLVVQKSGSGALGSQPQVQVSPQNI 70 Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR-DKYHATAVFDGVTVLTINDT 361 V G+ R C ATG P P + W G + P +R D+ + L I D Sbjct: 71 QVHEGDTLRMYCRATGSPTPRLSWLKNGG---LLPAQARMDR-------TDIGTLLIPDV 120 Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421 +DS T +C N GS+ K+TV D+ P ++ PS + C A Sbjct: 121 QLSDS-GTYMCVGSNSIGSNSAPVKVTVLK-ADQSFPAVSIQPSTADIQEGQSLELNCVA 178 Query: 422 ICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 P P ++W+ L NH+ V + +L DSG YTC HG Sbjct: 179 PGNPPPKVSWW-RASGLSSNHQ--VLGNQLRIL-SATAEDSGEYTCRVEGNHG 227 Score = 83.4 bits (197), Expect = 3e-14 Identities = 68/252 (26%), Positives = 103/252 (40%), Gaps = 29/252 (11%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68 G P + P ++ V + CRA GSP+P + W K G L+ + G L Sbjct: 58 GSQPQVQVSPQNIQVHEGDTLRMYCRATGSPTPRLSWLKNGGLLPAQARMDRTDIGTLLI 117 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-----FRLEPESKQSAQGD 123 SD+G Y C +NS G S +A + V VL+ + ++P + +G Sbjct: 118 PDVQ----LSDSGTYMCVGSNSIG---SNSAPVKVTVLKADQSFPAVSIQPSTADIQEGQ 170 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183 ++ L C+ P G+P P V W + G S H V G L I A D+G Y C Sbjct: 171 SLELNCVAP-GNPPPKVSWWR------ASGLSSNHQVLGNQLRILSATAEDSGEYTCRVE 223 Query: 184 NAAGTRESA--IATLKIHI--------KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233 G S AT+ + + P + P V + G + TF+CR+ P Sbjct: 224 GNHGNPSSGGHQATVSVSVTSSSSRLQSPIIAIEPHSAVVRVGETATFRCRIYSGAQPVR 283 Query: 234 LWRRSAGGGNMP 245 L + A ++P Sbjct: 284 LEWKVANNQHLP 295 >UniRef50_O18465 Cluster: Tractin; n=7; Coelomata|Rep: Tractin - Hirudo medicinalis (Medicinal leech) Length = 1880 Score = 146 bits (354), Expect = 3e-33 Identities = 138/485 (28%), Positives = 195/485 (40%), Gaps = 46/485 (9%) Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAG-GLFFLRATHGR 75 P + T + + C A G+P +W+K G L S+ R G L + Sbjct: 40 PYESTFKNMEEVEIPCEATGTPPLVFQWFKDGEPLEKSEAERPFKDEDQGTITL---YNN 96 Query: 76 VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL--EPESKQSAQGDTVVLECLPPR 133 D G Y C N YGTA S L +AV +E F EP+ GD + L C PP+ Sbjct: 97 ELKDEGYYQCIVKNKYGTAASVKTLLKMAV-QESFPTVKEPQIVNVRVGDNLTLRCNPPK 155 Query: 134 GSPEPNVYW---KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTD---AGRYQCIARNAAG 187 P P+VYW KK + L + R +L GN + + D Y CI+ N A Sbjct: 156 SYPTPDVYWGTVKKGAKLLPLENTMRYNLDYEGNFHFANVMEEDHREGAYYLCISHNNAM 215 Query: 188 TRE------------SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235 S+ ++ H + T P +A TG S +C G P P+V W Sbjct: 216 RSSVQGNDCIIRINGSSKDGVRKHAPGVMWTSPRKDLALTGQSKKLKCIFSGYPTPNVSW 275 Query: 236 RRSAGGGNMPLGRVKVLDD--GSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDP 292 S G + P ++ V + L + NV + D G Y C ++ G AV LTV Sbjct: 276 --SKRGSDFP-PKIVVSSELPHELEIRNVEVGDAGTYRCTGSSTYGKAVFVDIELTVESM 332 Query: 293 P--SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350 P N P VN A F C G P PT+ W + P R + + Sbjct: 333 PRWKDNKPPEDVNTSDEETAVFKCGVEGIPRPTVEWMLNKRPLEDLPPNPRMRMN----- 387 Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP-SNQTL 409 D TVLT ++ D + I C+A N G L V ++ PP + P S L Sbjct: 388 DERTVLTFSNVSSKDIQ-VIQCNASNVHGYILANAYLNVFAE----PPSFQDLPVSPMKL 442 Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469 V C+ P+P++ + +I R V G L++ +L SDSG Y C A Sbjct: 443 TEGKNTVVQCSVFGAPKPLVTC-LRNDTVISGDRFKVDTHGNLLVSNLQLSDSGNYICFA 501 Query: 470 SSRHG 474 S++ G Sbjct: 502 SNKFG 506 Score = 97.1 bits (231), Expect = 3e-18 Identities = 124/487 (25%), Positives = 194/487 (39%), Gaps = 49/487 (10%) Query: 15 IEQPLDVTVARHQPATLNCRAGGS-PSPAIRW---YKGGVLV-VSDTHRSILPAGGLFFL 69 +++P V V TL C S P+P + W KG L+ + +T R L G F Sbjct: 133 VKEPQIVNVRVGDNLTLRCNPPKSYPTPDVYWGTVKKGAKLLPLENTMRYNLDYEGNFHF 192 Query: 70 RATHGRVHSDAGVYWCEATNSY--GTARSRNATLHV-AVLREEFR--------LEPESKQ 118 H + Y C + N+ + + + + + ++ R P Sbjct: 193 ANVMEEDHREGAYYLCISHNNAMRSSVQGNDCIIRINGSSKDGVRKHAPGVMWTSPRKDL 252 Query: 119 SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY 178 + G + L+C+ G P PNV W K G F + L I++ DAG Y Sbjct: 253 ALTGQSKKLKCIFS-GYPTPNVSWSKRGSD--FPPKIVVSSELPHELEIRNVEVGDAGTY 309 Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLW- 235 +C + G L + P PEDV + F+C V G P P V W Sbjct: 310 RCTGSSTYGKAVFVDIELTVESMPRWKDNKPPEDVNTSDEETAVFKCGVEGIPRPTVEWM 369 Query: 236 -RRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-DP 292 + P R+++ D+ + L NV D C A N G + A+ YL V+ +P Sbjct: 370 LNKRPLEDLPPNPRMRMNDERTVLTFSNVSSKDIQVIQCNASNVHGYILANAYLNVFAEP 429 Query: 293 PSINLSPNS-VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 PS P S + + G C+ G P+P + + N T+I S D++ D Sbjct: 430 PSFQDLPVSPMKLTEGKNTVVQCSVFGAPKPLV--TCLRNDTVI----SGDRFKV----D 479 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411 L +++ +DS N I C A N G+ V L V + I+ PS+ + Sbjct: 480 THGNLLVSNLQLSDSGNYI-CFASNKFGNDSVGANLIVRRRTE-----ISRPPSDHVTTV 533 Query: 412 KSMAVFPCTAICTPEP----IIAWYFEGEAL-IQNHRRNVTN--DGTLVLKDLDKSDSGT 464 S V C A PE + W +GE + + V + D +L +K ++ +SGT Sbjct: 534 GSEVVLHCNATTDPEEKNSLSVKWLKDGEPITFEGSSPGVFDFRDNSLTIKKVEVKESGT 593 Query: 465 YTCVASS 471 Y C+AS+ Sbjct: 594 YVCIAST 600 Score = 83.4 bits (197), Expect = 3e-14 Identities = 108/379 (28%), Positives = 144/379 (37%), Gaps = 24/379 (6%) Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86 Q L C G P+P + W K G SD I+ + L DAG Y C Sbjct: 257 QSKKLKCIFSGYPTPNVSWSKRG----SDFPPKIVVSSELPHELEIRNVEVGDAGTYRCT 312 Query: 87 ATNSYGTARSRNATLHVAVL-REEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145 +++YG A + L V + R + PE ++ +T V +C G P P V W N Sbjct: 313 GSSTYGKAVFVDIELTVESMPRWKDNKPPEDVNTSDEETAVFKC-GVEGIPRPTVEWMLN 371 Query: 146 GQTLL-FDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY 203 + L + RM + D L + D QC A N G A A L + +P Sbjct: 372 KRPLEDLPPNPRMRMNDERTVLTFSNVSSKDIQVIQCNASNVHGYI-LANAYLNVFAEPP 430 Query: 204 LITG-PEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDN 261 P + T G + QC V G P P V R+ + R KV G+L + N Sbjct: 431 SFQDLPVSPMKLTEGKNTVVQCSVFGAPKPLVTCLRN--DTVISGDRFKVDTHGNLLVSN 488 Query: 262 VILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPE 321 + L+D G Y C A N G S L V I+ P+ G+ C AT PE Sbjct: 489 LQLSDSGNYICFASNKFGNDSVGANLIVRRRTEISRPPSDHVTTVGSEVVLHCNATTDPE 548 Query: 322 PTMFWSV---EGNRTIIFPGMSRDKYHATAVFD-GVTVLTINDTDKNDSRNTIVCSAVNY 377 SV + I F G S VFD LTI + +S T VC A Sbjct: 549 EKNSLSVKWLKDGEPITFEGSS------PGVFDFRDNSLTIKKVEVKES-GTYVCIASTD 601 Query: 378 AGSSFVRGKLTVTSDDDRP 396 S + +L V D P Sbjct: 602 LDSDNITVELVVKGVPDPP 620 Score = 50.4 bits (115), Expect = 3e-04 Identities = 25/91 (27%), Positives = 41/91 (45%), Gaps = 3/91 (3%) Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNV 446 +T + +RPP I + P T PC A TP + W+ +GE L ++ Sbjct: 23 MTFQKEVNRPPSITAHPPYESTFKNMEEVEIPCEATGTPPLVFQWFKDGEPLEKSEAERP 82 Query: 447 TND---GTLVLKDLDKSDSGTYTCVASSRHG 474 D GT+ L + + D G Y C+ +++G Sbjct: 83 FKDEDQGTITLYNNELKDEGYYQCIVKNKYG 113 Score = 50.0 bits (114), Expect = 4e-04 Identities = 55/239 (23%), Positives = 90/239 (37%), Gaps = 16/239 (6%) Query: 253 DDGSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINL--SPNSVNVESGNV 309 D G++ L N L DEG Y C +N G A S L + S P VNV G+ Sbjct: 87 DQGTITLYNNELKDEGYYQCIVKNKYGTAASVKTLLKMAVQESFPTVKEPQIVNVRVGDN 146 Query: 310 ARFTCTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG-VTVLTINDTDKNDSR 367 C P P ++W + P + +Y+ ++G + + D + Sbjct: 147 LTLRCNPPKSYPTPDVYWGTVKKGAKLLPLENTMRYNLD--YEGNFHFANVMEEDHREGA 204 Query: 368 NTIVCSAVNYAGSSFVRG-----KLTVTSDDD---RPPPIITNGPSNQTLPIKSMAVFPC 419 + C + N A S V+G ++ +S D P ++ P C Sbjct: 205 YYL-CISHNNAMRSSVQGNDCIIRINGSSKDGVRKHAPGVMWTSPRKDLALTGQSKKLKC 263 Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVW 478 P P ++W G + L +++++ D+GTY C SS +GK V+ Sbjct: 264 IFSGYPTPNVSWSKRGSDFPPKIVVSSELPHELEIRNVEVGDAGTYRCTGSSTYGKAVF 322 >UniRef50_O01761 Cluster: Muscle M-line assembly protein unc-89; n=12; Caenorhabditis|Rep: Muscle M-line assembly protein unc-89 - Caenorhabditis elegans Length = 8081 Score = 146 bits (354), Expect = 3e-33 Identities = 178/689 (25%), Positives = 281/689 (40%), Gaps = 110/689 (15%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAG 64 VT+ + P + DV QP L C+ SP P + WYK G +V SD + L Sbjct: 5695 VTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPD 5754 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARS----------RNATLHVAVLREEFR--- 111 G+ L V+ D G+Y ATN GTA+ R++ + R+ F Sbjct: 5755 GVATLLIP-SCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGARRSADRDVFDANK 5813 Query: 112 ----LEP-ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-- 164 +EP E+ + + + L C G P+P + W K+G+ + G R+ L++ + Sbjct: 5814 APKLMEPLENIRIPEKQSFRLRC-KFSGDPKPTIKWFKDGERVFPYG--RLQLIESPDGV 5870 Query: 165 --LVIQDARQTDAGRYQCIARNAAGTRESA--IATLKIHIKPYLI------------TGP 208 LV+ A + DAG Y+C+A N G+ ++ + ++ KP I T P Sbjct: 5871 CELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTP 5930 Query: 209 EDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDGSLRL--DNVI 263 + A+ G SVTF+C G+P P + W + G ++K+ DG+ RL +V Sbjct: 5931 LTIRRAKPGDSVTFECLPFGNPFPSIKWLKD-GLELFSDEKIKMEAAADGTQRLILSDVT 5989 Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDP--------PSINLSPN-----------SVNV 304 EG + C A N G S L + P +N P ++++ Sbjct: 5990 FLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGEPEECKPRIRRGLYNMSI 6049 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 GNV ATG P PT+ W +G + I+ G + T G+ L I + + Sbjct: 6050 HEGNVVEMIVCATGIPTPTVKWYKDG-QEIVGDGPDGKRVIFTDE-RGIHHLVIVNASPD 6107 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLT------VTSDDDRP----PPIITNGPSNQTLPIKSM 414 D A N GS+ G L + D+R PP N+ + Sbjct: 6108 D-EGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFVRQLKNKHVFNHMP 6166 Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG----TLVLKDLDKSDSGTYTCVAS 470 +F C + P P + W+ G+ ++ R + + G L++ D D+G Y A Sbjct: 6167 TIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIILDTTLEDAGEYVATAK 6226 Query: 471 SRHGKYVWSGALLVDSPINPNIHF---------------FRAADVSSLPGPPTK-PITHN 514 + HG S L V P +I F F+ + +SLP PP + P Sbjct: 6227 NSHGSASSSAVLDVTVPFLDSIKFNGEIDVTPYLTEEYGFKKLNTASLPTPPDRGPFIKE 6286 Query: 515 VTDTSVTLSWSQNNKIGSS-SILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYV 573 VT +TLSW + + Y +E+ RE + W ++ + + Sbjct: 6287 VTGHYLTLSWIPTKRAPPRYPQVTYVIEI--REL--------PEKQWSLLEYNIPEPVCK 6336 Query: 574 VKSLIPGITYMFIVRTENSHGLSGPSPVS 602 V++L G +Y F VR EN +G+S PSP S Sbjct: 6337 VRNLELGKSYQFRVRAENIYGISDPSPAS 6365 Score = 140 bits (339), Expect = 2e-31 Identities = 139/499 (27%), Positives = 208/499 (41%), Gaps = 62/499 (12%) Query: 28 PATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL-PAGGLFFLRATHGRVHSDAGVYWCE 86 P + C +P+ + W+K G + H I G ++ SD GVY C Sbjct: 5293 PMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIKIIPFE-ESDIGVYMCV 5351 Query: 87 ATNSYGTARSRNATLHVAVL-------REEF--RLEP--ESKQSAQGDTVVLECLPPRGS 135 A N G A ++ AT V +L R E+ ++ P E K G + L C Sbjct: 5352 AVNELGQAETQ-ATYQVEILEHVEEEKRREYAPKINPPLEDKTVNGGQPIRLSC-KVDAI 5409 Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGT-RESA 192 P +V W K+G L D + + + G L I D+ + D G Y+C+A NA GT S Sbjct: 5410 PRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINTSC 5469 Query: 193 IATLKI---HIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG-GGN 243 +K+ +K P+ G D+ A G S T +C V GDP P++ W R+ N Sbjct: 5470 SVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRN 5529 Query: 244 MPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY----------- 290 P ++ DG SL ++ ++DEG Y CEAEN+ G V Sbjct: 5530 GPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKM 5589 Query: 291 ---DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347 PP L + ++V GNV C TG P P++ WS +G I SR ++ + Sbjct: 5590 DEGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLI---EDSRFEW-SN 5645 Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT-NGPSN 406 GV L I + +D T C A N GS+ K V DD ++T + P Sbjct: 5646 EASKGVYQLRIKNATVHD-EGTYRCVATNENGSATT--KSFVRMDDGLGSGVVTASQPPR 5702 Query: 407 QTLPIKSMAV-------FPCTAICTPEPIIAWYFEGEALIQNHRRNV--TNDG--TLVLK 455 TL + + C +P P + WY +G + + R + + DG TL++ Sbjct: 5703 FTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDGVATLLIP 5762 Query: 456 DLDKSDSGTYTCVASSRHG 474 D G Y +A++ G Sbjct: 5763 SCVYDDDGIYRVIATNPSG 5781 Score = 139 bits (336), Expect = 5e-31 Identities = 142/521 (27%), Positives = 221/521 (42%), Gaps = 71/521 (13%) Query: 15 IEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73 I PL D TV QP L+C+ P ++ WYK G+ + +D+ SI A + Sbjct: 5385 INPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAIN 5444 Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK---------QSAQGDT 124 D G Y C ATN++GT + + +++V V ++E + E E + +GD+ Sbjct: 5445 DSTEEDIGAYRCVATNAHGTINT-SCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDS 5503 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM--HLVDGG-NLVIQDARQTDAGRYQCI 181 L+C G P P + W +NGQ LL +G + DG +L + ++ +D G Y+C Sbjct: 5504 FTLKC-AVTGDPFPEIKWYRNGQ-LLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCE 5561 Query: 182 ARNAAG-TRESAIATLKIHI----KPYLITGP--------EDVVAQTGSSVTFQCRVGGD 228 A NA G + A A +++ + KP + G D+ G+ + +C+V G Sbjct: 5562 AENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGL 5621 Query: 229 PLPDVLWRRSAGGGNMPLGRVKVLDDGS-----LRLDNVILADEGEYSCEAENSVGAVS- 282 P P V W + GG + R + ++ S LR+ N + DEG Y C A N G+ + Sbjct: 5622 PNPSVKWSKD-GGPLIEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATT 5680 Query: 283 ----------ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332 SG +T PP L V G + C P P M W +G Sbjct: 5681 KSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDG-- 5738 Query: 333 TIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV--- 389 I+ P D+ + DGV L I +D V A N +G++ +G TV Sbjct: 5739 AIVTPS---DRIQISLSPDGVATLLIPSCVYDDDGIYRVI-ATNPSGTAQDKGTATVKKL 5794 Query: 390 --------TSD----DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437 ++D D P + N +P K C P+P I W+ +GE Sbjct: 5795 PRDSGARRSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGER 5854 Query: 438 LIQNHRRNV--TNDGT--LVLKDLDKSDSGTYTCVASSRHG 474 + R + + DG LV+ + D+G Y CVA + +G Sbjct: 5855 VFPYGRLQLIESPDGVCELVVDSATRQDAGGYRCVAENTYG 5895 Score = 136 bits (328), Expect = 5e-30 Identities = 127/499 (25%), Positives = 210/499 (42%), Gaps = 32/499 (6%) Query: 7 TSGEAPYIIEQPLDVT-VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL--PA 63 T EAP + EQ L T V + + + GGS +P + W+K V D + + P Sbjct: 3184 TKVEAP-VFEQGLKKTSVKEKEEIKMEVKVGGS-APDVEWFKDDKPVSEDGNHEMKKNPE 3241 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQG 122 G+F L +DAG Y +A+N GTA S A + ++ + F E + + Sbjct: 3242 TGVFTLVVKQAAT-TDAGKYTAKASNPAGTAESSAEAEVTQSLEKPTFVRELVTTEVKIN 3300 Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG---NLVIQDARQTDAGRYQ 179 +T L + +G P+P+V W K+GQ + D + V+G ++ I+DAR D+G+Y Sbjct: 3301 ETATLS-VTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYA 3359 Query: 180 CIARNAAGTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 C A N AG E+ A +K + P + + + S T +V G P P V W + Sbjct: 3360 CRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFK 3419 Query: 238 SAGGGNMP----LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYD- 291 ++ + + + SL +++ D G YSC A N G A++ + + + D Sbjct: 3420 DDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRARNEAGEALTTANFGIIRDS 3479 Query: 292 -PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350 PP + V T G P P + W + ++ I + A Sbjct: 3480 IPPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEW-FKDDKPI---NIDNSHIFAKDEG 3535 Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410 G LTI + + C A N AG + + V + + P + G + Sbjct: 3536 SGHHTLTIKQA-RGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAP--LFVQGLKPYEVE 3592 Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-----TLVLKDLDKSDSGTY 465 A PEP + W+ +G + +++ + G TLV+KD + +D G Y Sbjct: 3593 QGKPAELVVRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLVIKDTNNADFGKY 3652 Query: 466 TCVASSRHGKYVWSGALLV 484 TC A+++ GK G L + Sbjct: 3653 TCQATNKAGKDETVGELKI 3671 Score = 135 bits (327), Expect = 6e-30 Identities = 129/483 (26%), Positives = 199/483 (41%), Gaps = 34/483 (7%) Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88 A + + G P P I WYK V + D + FF +D G Y C AT Sbjct: 565 AKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCMAT 624 Query: 89 NSYGTARSRNATLHVAVLREE-----FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWK 143 N YG A S +A V + +E F + K+ +GD + EC G PEP + W Sbjct: 625 NEYGQA-STSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFEC-EVEGWPEPELVWL 682 Query: 144 KNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGTRESAIATL----- 196 + Q L D R+ DG L I+DA+ D G Y +N G+ ES Sbjct: 683 VDDQPLRPSHDFRLQ-YDGQTAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADP 741 Query: 197 -KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK-VLDD 254 K H+ P E V G V F+ + GDP P+++W + G +VK + +D Sbjct: 742 DKNHVAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFIN-GKPLSESEKVKFISED 800 Query: 255 G--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---DPPSINLSPNSVNVESGNV 309 G L + +V +G +C+ N +G+ S G L V PP+ N V+ + Sbjct: 801 GICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDKTVQEKST 860 Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369 F +G PEPT+ +++ G + ++ DG ++I +T + Sbjct: 861 VVFEVDVSGWPEPTLTFTLCGKEL-----KNGEEGVEIVGHDGFYRISIPNTSMDKHDGE 915 Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDD--RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427 IV A N G++ R +LTV +++ R P +QT+ AVF T P P Sbjct: 916 IVAKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNP 975 Query: 428 IIAWYFEGEALIQNH---RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 + W+ G + Q + N + D +GT C A + G++ L+V Sbjct: 976 EVTWFINGHKMDQGSPGVKIEAHNHDHKLTID-SAQYAGTVLCRAENAVGRFETKARLVV 1034 Query: 485 DSP 487 +P Sbjct: 1035 LAP 1037 Score = 126 bits (303), Expect = 5e-27 Identities = 139/544 (25%), Positives = 222/544 (40%), Gaps = 78/544 (14%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68 GE P+ + +D+ R TL C G P P I+WY+ G L+ + I + Sbjct: 5484 GEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSC 5543 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV--AVLREE-----------FRLEPE 115 + SD G+Y CEA N++G A+++ AT HV A+ + E F LE Sbjct: 5544 SLTVNESTMSDEGIYRCEAENAHGKAKTQ-ATAHVQMALGKTEKPKMDEGKPPKFILELS 5602 Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-----LVIQDA 170 + G+ + LEC G P P+V W K+G L+ DSR + + L I++A Sbjct: 5603 DMSVSLGNVIDLEC-KVTGLPNPSVKWSKDGGPLI--EDSRFEWSNEASKGVYQLRIKNA 5659 Query: 171 RQTDAGRYQCIARNAAGTRES-AIATLKIHIKPYLITGPE---------DVVAQTGSSVT 220 D G Y+C+A N G+ + + + + ++T + DV G + Sbjct: 5660 TVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTTEGQPLK 5719 Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDG--SLRLDNVILADEGEYSCEAEN 276 +C+V PLP+++W + G P R+++ DG +L + + + D+G Y A N Sbjct: 5720 LECKVDASPLPEMVWYKD-GAIVTPSDRIQISLSPDGVATLLIPSCVYDDDGIYRVIATN 5778 Query: 277 SVGAVSASGYLTVYDPP--------------SINLSP------NSVNVESGNVARFTCTA 316 G G TV P N +P ++ + R C Sbjct: 5779 PSGTAQDKGTATVKKLPRDSGARRSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKF 5838 Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376 +G P+PT+ W +G R +FP + DGV L ++ + D+ C A N Sbjct: 5839 SGDPKPTIKWFKDGER--VFP---YGRLQLIESPDGVCELVVDSATRQDA-GGYRCVAEN 5892 Query: 377 YAGSSFVRGKLTVTSDDDRPPPI---ITNGPS-NQTLPIK-------SMAVFPCTAICTP 425 GS+ + V D +P I I G + T P+ F C P Sbjct: 5893 TYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTPLTIRRAKPGDSVTFECLPFGNP 5952 Query: 426 EPIIAWYFEGEALIQNH--RRNVTNDGT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481 P I W +G L + + DGT L+L D+ G + CVA++ HG Sbjct: 5953 FPSIKWLKDGLELFSDEKIKMEAAADGTQRLILSDVTFLSEGYFRCVATNEHGTASTKAE 6012 Query: 482 LLVD 485 L+++ Sbjct: 6013 LVIE 6016 Score = 124 bits (298), Expect = 2e-26 Identities = 126/498 (25%), Positives = 203/498 (40%), Gaps = 46/498 (9%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI--LPAGGLF 67 E P + + + V ++ ATL+ G P P++ W K G V +D+ I + G + Sbjct: 3284 EKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSY 3343 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEF--RLEPESKQSAQGDT 124 + R+ D+G Y C ATN G A++ N + ++ EF +L P + + T Sbjct: 3344 SITIKDARLE-DSGKYACRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKEKESTT 3402 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGD---SRMHLVDGGNLVIQDARQTDAGRYQCI 181 + ++ + G+PEP+V W K+ + D + V +L I DARQ D G Y C Sbjct: 3403 LSVKVV---GTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCR 3459 Query: 182 ARNAAG--TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239 ARN AG + ++ I P + + ++ + V G P+P+V W + Sbjct: 3460 ARNEAGEALTTANFGIIRDSIPPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEWFKDD 3519 Query: 240 GGGNMPLGRVKVLDDGS----LRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDP 292 N+ + D+GS L + D G Y+C+A N G + + V + Sbjct: 3520 KPINIDNSHIFAKDEGSGHHTLTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEA 3579 Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV--F 350 P VE G A G+PEP + W +G I D H Sbjct: 3580 PLFVQGLKPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAI------DNQHVIEKKGE 3633 Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV--------TSDDDRPPPIITN 402 +G L I DT+ D C A N AG G+L + T+++ +P + Sbjct: 3634 NGSHTLVIKDTNNADF-GKYTCQATNKAGKDETVGELKIPKYSFEKQTAEEVKP---LFI 3689 Query: 403 GPSNQTLPIK-SMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRR-NVTNDGT--LVLKDL 457 P +T ++ V C P I ++ + + I H + V DG L +++ Sbjct: 3690 EPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNIKLTIQNA 3749 Query: 458 DKSDSGTYTCVASSRHGK 475 K D G Y C A + GK Sbjct: 3750 KKEDVGAYRCEAVNVAGK 3767 Score = 112 bits (270), Expect = 5e-23 Identities = 127/493 (25%), Positives = 204/493 (41%), Gaps = 39/493 (7%) Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGG 65 T AP +E TV Q A L C+ G P P I+W K G V +S R+ G Sbjct: 3812 TGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDG 3871 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---- 121 L +DAG Y CEA N YG+A + + L +++ E+ Q Sbjct: 3872 TLTL-TFDNVTQADAGEYRCEAENEYGSAWTEGPI--IVTLEGAPKIDGEAPDFLQPVKP 3928 Query: 122 -----GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTD 174 G+T VLE G P+P+V W KNG+ L ++ +D G L + +A+ D Sbjct: 3929 AVVTVGETAVLEG-KISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLTVTNAKLDD 3987 Query: 175 AGRYQCIARNAAGTRESAIA-TLK--IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231 Y+C A N G S + T+K + P + + + F+C+V G P Sbjct: 3988 MDEYRCEASNEFGDVWSDVTLTVKEPAQVAPGFFKELSAIQVKETETAKFECKVSGTK-P 4046 Query: 232 DVLWRRSAGGGNMPLGRV--KVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYL 287 DV W + G RV + DDG+ RL ++ D+G Y E N G ++ L Sbjct: 4047 DVKWFKD-GTPLKEDKRVHFESTDDGTQRLVIEDSKTDDQGNYRIEVSNDAGVANSKVPL 4105 Query: 288 TVYDPPSINLSP--NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345 TV ++ + VNV G + G+P+ T+ W +G T+ S Sbjct: 4106 TVVPSETLKIKKGLTDVNVTQGTKILLSVEVEGKPK-TVKW-YKGTETV----TSSQTTK 4159 Query: 346 ATAVFDGVTVLTINDTDKNDS-RNTIVCSAVNYAGSSFVRGKLTVTSDDDR-PPPIITNG 403 V + L I + +D+ +V S +++ S +TVT ++ P G Sbjct: 4160 IVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVES--SATVTVTKAAEKISLPSFKKG 4217 Query: 404 PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDS 462 ++Q++P + V P+ + WY G+ + ++ N L + D + D Sbjct: 4218 LADQSVPKGTPLVLEVEIEGKPKD-VKWYKNGDEIKDGKVEDLGNGKYRLTIPDFQEKDV 4276 Query: 463 GTYTCVASSRHGK 475 G Y+ A++ G+ Sbjct: 4277 GEYSVTAANEAGE 4289 Score = 107 bits (257), Expect = 2e-21 Identities = 120/492 (24%), Positives = 196/492 (39%), Gaps = 35/492 (7%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P +++ P VT+ + A G P+P ++W +V + + ++ L+ Sbjct: 2075 PIVVDGPKSVTIKETETAEFKATISGFPAPTVKWTINEKIVEESRTITTIKTEDVYTLKI 2134 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGDTVVLEC 129 ++ ++ G A NS G S+ A L V V +F+ + K + +G+ + Sbjct: 2135 SNAKI-EQTGTVKVTAQNSAG-QDSKQADLKVEPNVKAPKFKSQLTDKVADEGEPLRWNL 2192 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG----NLVIQDARQTDAGRYQCIARNA 185 SP V W NGQ L + +VD G ++ I +A+ +G A+NA Sbjct: 2193 ELDGPSPGTEVSWLLNGQPL--TKSDTVQVVDHGDGTYHVTIAEAKPEMSGTLTAKAKNA 2250 Query: 186 AGTRE-SAIATLK-IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSA 239 AG E SA T+ + KP + P++ SV F V G P+P+V W ++ Sbjct: 2251 AGECETSAKVTVNGGNKKPEFVQAPQNHETTLEESVKFSAIVTGKPMPNVTWYLNNKKLI 2310 Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDPPSIN 296 + + V S+R+ ++ G EAEN G V A+ L V + P Sbjct: 2311 QSEEVKVKYVHETGKTSIRIQKPLMEHNGTIRVEAENVSGKVQATAQLKVDKKTEVPKFT 2370 Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS-RDKYHATAVFDGVTV 355 + + V+ G +FT G PEP++ W++ G P ++ DK DG Sbjct: 2371 TNMDDRQVKEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHPNITVTDK-------DGEHT 2423 Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415 + I+ + + C A N GS +L V D P ++ + + Sbjct: 2424 IEISAVTP-EQAGELSCEATNPVGSKKRDVQLAVKKVGD--APTFAKNLEDRLITEGELT 2480 Query: 416 VFPCTA-ICTPEPIIAWYFEG-EALIQNHRRNV-TNDGTLVLKDLDK--SDSGTYTCVAS 470 + I P+P I W +G E H + V DG+L L L D G T A Sbjct: 2481 LMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAE 2540 Query: 471 SRHGKYVWSGAL 482 S G S +L Sbjct: 2541 SEFGVAECSASL 2552 Score = 106 bits (255), Expect = 3e-21 Identities = 116/490 (23%), Positives = 195/490 (39%), Gaps = 39/490 (7%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 +AP I D T + L C+ G P P + W + ++ ++ G+ + Sbjct: 2992 KAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQES-ITVESVEGVERV 3050 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 T + S G Y C A N+ GT+++ A L V F E ++K+ + G+ +VL C Sbjct: 3051 TITSSEL-SHQGKYTCIAENTEGTSKT-EAFLTVQGEAPVFTKELQNKELSIGEKLVLSC 3108 Query: 130 LPPRGSPEPNVYWKKNGQTLLFD----GDSRMHLV-DGGN----LVIQDARQTDAGRYQC 180 +GSP+P+V + +T + SR+ + D N +VI + D Y+ Sbjct: 3109 -SVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDIVSYKA 3167 Query: 181 IARNAAGTRES-AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS- 238 IA N+ GT S + T K+ P G + + + + +VGG PDV W + Sbjct: 3168 IATNSIGTATSTSKITTKVE-APVFEQGLKKTSVKEKEEIKMEVKVGGS-APDVEWFKDD 3225 Query: 239 ---AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDP 292 + GN + + +L + D G+Y+ +A N G +S V + Sbjct: 3226 KPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQSLEK 3285 Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD- 351 P+ + V+ A + T G P+P++ W +G + D H A + Sbjct: 3286 PTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQ------PVQTDSSHVIAKVEG 3339 Query: 352 -GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410 G +TI D DS C A N AG + V + PP S + Sbjct: 3340 SGSYSITIKDARLEDS-GKYACRATNPAGEAKTEANFAVVK--NLVPPEFVEKLSPLEVK 3396 Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEAL-IQN----HRRNVTNDGTLVLKDLDKSDSGTY 465 K + TPEP + W+ + + I N ++ +L + D + D G Y Sbjct: 3397 EKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIY 3456 Query: 466 TCVASSRHGK 475 +C A + G+ Sbjct: 3457 SCRARNEAGE 3466 Score = 104 bits (249), Expect = 2e-20 Identities = 126/505 (24%), Positives = 191/505 (37%), Gaps = 36/505 (7%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68 GEAP ++ + ++ + L+C GSP P + +Y +T + + Sbjct: 3084 GEAPVFTKELQNKELSIGEKLVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEH 3143 Query: 69 LRA-THGRV------HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121 + TH R+ D Y ATNS GTA S T + E E K+++ Sbjct: 3144 DQTNTHWRMVISQITKEDIVSYKAIATNSIGTATS---TSKITTKVEAPVFEQGLKKTSV 3200 Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL-VDGG--NLVIQDARQTDAGRY 178 + ++ G P+V W K+ + + DG+ M + G LV++ A TDAG+Y Sbjct: 3201 KEKEEIKMEVKVGGSAPDVEWFKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKY 3260 Query: 179 QCIARNAAGTRES---AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235 A N AGT ES A T + KP + + + T V G P P V W Sbjct: 3261 TAKASNPAGTAESSAEAEVTQSLE-KPTFVRELVTTEVKINETATLSVTVKGVPDPSVEW 3319 Query: 236 RRSAGGGNMPLGRV--KVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291 + V KV G S+ + + L D G+Y+C A N G V Sbjct: 3320 LKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVK 3379 Query: 292 ---PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348 PP + + V+ + G PEP++ W + I K A Sbjct: 3380 NLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVG 3439 Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408 F LTIND + D C A N AG + + D PP T Sbjct: 3440 SFS----LTINDARQGDV-GIYSCRARNEAGEALTTANFGIIRDS--IPPEFTQKLRPLE 3492 Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDG----TLVLKDLDKSDSG 463 + + T I TP P + W+ + + + I N ++G TL +K D G Sbjct: 3493 VREQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQARGEDVG 3552 Query: 464 TYTCVASSRHGKYVWSGALLVDSPI 488 YTC A++ G+ + + V I Sbjct: 3553 VYTCKATNEAGEAKTTANMAVQEEI 3577 Score = 102 bits (245), Expect = 5e-20 Identities = 117/404 (28%), Positives = 165/404 (40%), Gaps = 33/404 (8%) Query: 11 APYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFF 68 AP +PL D TV G P P + + G L + I+ G + Sbjct: 842 APPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYR 901 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP------ESKQSAQG 122 + + + G +A N +GTA SR A L V EE R P E + G Sbjct: 902 ISIPNTSMDKHDGEIVAKAQNEHGTAESR-ARLTVEQEEEESRSAPTFLKDIEDQTVKTG 960 Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN----LVIQDARQTDAGRY 178 + V E RG+P P V W NG + D S ++ N L I A+ AG Sbjct: 961 EFAVFETTV-RGNPNPEVTWFINGHKM--DQGSPGVKIEAHNHDHKLTIDSAQY--AGTV 1015 Query: 179 QCIARNAAGTRES-----AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233 C A NA G E+ +A K P + D ++V F+ RV G+P P V Sbjct: 1016 LCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTV 1075 Query: 234 LWRRSAGGGNMPLGRVKVLD-DGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVY 290 W G RV++ + DGS+++ N+ + D GE A NS G+ LTV Sbjct: 1076 TWYLK-GEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQ 1134 Query: 291 DPP---SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347 P +L P S+ VE G+ A F+ A G P PT WSV G + +R + Sbjct: 1135 KKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWSVNGRKVRDGQEGARVTRDES 1194 Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAV--NYAGSSFVRGKLTV 389 V DG ++LTI+ N + S V N G+ +LT+ Sbjct: 1195 TV-DGASILTIDTATYYSEVNHLTISVVAENTLGAEETGAQLTI 1237 Score = 99.5 bits (237), Expect = 5e-19 Identities = 125/500 (25%), Positives = 188/500 (37%), Gaps = 54/500 (10%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA-GGLFFLRATHGRVHS 78 D V TL C G P P + W K GV++ D ++ A G LR + S Sbjct: 5079 DTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAK-KS 5137 Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREE-----FRLEPESKQSAQGDTVVLECLPPR 133 D G Y A N G+A S + + V E+ F + ++ + GD + R Sbjct: 5138 DIGQYRVTAKNEAGSATS-DCKVTVTEQGEQPSKPKFVIPLKTGAALPGDKKEFN-VKVR 5195 Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRES 191 G P+P + W NG + FD + + GN L I+D R+ D G +CIA+N GT E+ Sbjct: 5196 GLPKPTLQWFLNGIPIKFDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENGTDET 5255 Query: 192 AIATLK-----------IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 + + P D G + +C V +P +V W + Sbjct: 5256 VCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGK 5315 Query: 241 G-GNMPLGRVKVLDDGSLRLDNVIL--ADEGEYSCEAENSVG--AVSASGYLTVYD---- 291 + ++ DG+ R+ + +D G Y C A N +G A+ + + + Sbjct: 5316 KIEHTAHTEIRNTVDGACRIKIIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEE 5375 Query: 292 ------PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345 P IN V G R +C P ++ W +G P + + Sbjct: 5376 EKRREYAPKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDG-----LPLRADSRTS 5430 Query: 346 ATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG----SSFVRGKLTVTS-DDDRPPPII 400 DG L IND+ + D C A N G S V K+ + P Sbjct: 5431 IQYEEDGTATLAINDSTEEDI-GAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFF 5489 Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNV---TNDG--TLVLK 455 T G + C P P I WY G+ L++N R V + DG +L + Sbjct: 5490 TKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQ-LLRNGPRTVIETSPDGSCSLTVN 5548 Query: 456 DLDKSDSGTYTCVASSRHGK 475 + SD G Y C A + HGK Sbjct: 5549 ESTMSDEGIYRCEAENAHGK 5568 Score = 97.5 bits (232), Expect = 2e-18 Identities = 118/443 (26%), Positives = 172/443 (38%), Gaps = 64/443 (14%) Query: 4 DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63 D + +AP ++E ++ + Q L C+ G P P I+W+K G V ++ + Sbjct: 5807 DVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIES 5866 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARS----------RNATLHVAVLRE----E 109 DAG Y C A N+YG+AR+ R + +RE Sbjct: 5867 PDGVCELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPG 5926 Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVI 167 F +++ GD+V ECL P G+P P++ W K+G L D +M G L++ Sbjct: 5927 FTTPLTIRRAKPGDSVTFECL-PFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQRLIL 5985 Query: 168 QDARQTDAGRYQCIARNAAGTRESAIATLKI-------------------HIKPYLITGP 208 D G ++C+A N GT S A L I KP + G Sbjct: 5986 SDVTFLSEGYFRCVATNEHGT-ASTKAELVIEGDRTIGSRPLPEVNGEPEECKPRIRRGL 6044 Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPLGRVKVLDD----GSLRLDNV 262 ++ G+ V G P P V W + G+ P G+ + D L + N Sbjct: 6045 YNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDERGIHHLVIVNA 6104 Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSI---------NLSPNSV-NVESGNVAR- 311 DEGEYS EA N +G+ G L + P I P V +++ +V Sbjct: 6105 SPDDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFVRQLKNKHVFNH 6164 Query: 312 ----FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367 F C G P P + W G + I PG R K + G L I DT D+ Sbjct: 6165 MPTIFDCLVVGHPAPEVEWFHNGKK--IVPG-GRIKIQSCG--GGSHALIILDTTLEDA- 6218 Query: 368 NTIVCSAVNYAGSSFVRGKLTVT 390 V +A N GS+ L VT Sbjct: 6219 GEYVATAKNSHGSASSSAVLDVT 6241 Score = 96.3 bits (229), Expect = 4e-18 Identities = 125/542 (23%), Positives = 206/542 (38%), Gaps = 42/542 (7%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI--LPAGGLFFL 69 P ++ P + + + G P P + WY ++ + + G + Sbjct: 2269 PEFVQAPQNHETTLEESVKFSAIVTGKPMPNVTWYLNNKKLIQSEEVKVKYVHETGKTSI 2328 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVVL 127 R + + G EA N G ++ A L V E +F + +Q +G+ V Sbjct: 2329 RIQKPLMEHN-GTIRVEAENVSGKVQA-TAQLKVDKKTEVPKFTTNMDDRQVKEGEDVKF 2386 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAA 186 G PEP+V W NG+ + + + DG + + I AG C A N Sbjct: 2387 TA-NVEGYPEPSVAWTLNGEPVSKHPNITVTDKDGEHTIEISAVTPEQAGELSCEATNPV 2445 Query: 187 GT--RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGN 243 G+ R+ +A K+ P ED + G ++ P P + W + G Sbjct: 2446 GSKKRDVQLAVKKVGDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKD-GVEI 2504 Query: 244 MPLGRVKVLD--DGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVYD-----PPS 294 G K+++ DGSL+L L D+G + +AE+ G S L V P+ Sbjct: 2505 TSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAESEFGVAECSASLGVVKGRPMAKPA 2564 Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354 +N+ G+ TG P P + W + G + + + D + A +GV Sbjct: 2565 FQSDIAPINLTEGDTLECKLLITGDPTPFVKWYI-GTQLVC---ATEDTEISNA--NGVY 2618 Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPI-ITNGPSNQTLPIKS 413 + I+ D I C A N AG G L V + P P+ + T Sbjct: 2619 TMKIHGVTA-DMTGKIKCVAYNKAGEVSTEGPLKVVA----PIPVEFETSLCDATCREGD 2673 Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVAS 470 + PEP+++WY G+ L ++ + ++ T+ +KD+ SG C A Sbjct: 2674 TLKLRAVLLGEPEPVVSWYVNGKKLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAI 2733 Query: 471 SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVT---DTSVTLSWSQN 527 + +GK LLV P ++V + G TK + H V D +L+W N Sbjct: 2734 NEYGKATSEATLLVLPRGEPPDFLEWLSNVRARTG--TK-VVHKVVFTGDPKPSLTWYIN 2790 Query: 528 NK 529 NK Sbjct: 2791 NK 2792 Score = 92.7 bits (220), Expect = 6e-17 Identities = 126/525 (24%), Positives = 200/525 (38%), Gaps = 43/525 (8%) Query: 33 CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG 92 C G P P + W + +H L G D GVY + N +G Sbjct: 669 CEVEGWPEPELVWLVDDQ-PLRPSHDFRLQYDGQTAKLEIRDAQPDDTGVYTVKIQNEFG 727 Query: 93 TARSRNATLHVAV------LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146 + S+ A L V + EF+ E + +G+ V + + G P P + W NG Sbjct: 728 SIESK-AELFVQADPDKNHVAPEFQATIEYVECDEGEEVRFKSVIT-GDPNPEIIWFING 785 Query: 147 QTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205 + L + DG L I+D + G C N G+ S LK+ + P Sbjct: 786 KPLSESEKVKFISEDGICILTIKDVTRHFDGMVTCQGSNRLGSA-SCDGRLKVRVPPAPP 844 Query: 206 T--GP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR--VKVLD-DGSLRL 259 T P ED Q S+V F+ V G P P + + + G + G V+++ DG R+ Sbjct: 845 TFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTF--TLCGKELKNGEEGVEIVGHDGFYRI 902 Query: 260 D--NVIL-ADEGEYSCEAENSVGAVSASGYLTVYDP-------PSINLSPNSVNVESGNV 309 N + +GE +A+N G + LTV P+ V++G Sbjct: 903 SIPNTSMDKHDGEIVAKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEF 962 Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369 A F T G P P + W + G++ + G K A +T+ D T Sbjct: 963 AVFETTVRGNPNPEVTWFINGHK--MDQGSPGVKIEAHNHDHKLTI------DSAQYAGT 1014 Query: 370 IVCSAVNYAGSSFVRGKLTVTSDD-DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428 ++C A N G + +L V + + + PP ++T + + VF P+P Sbjct: 1015 VLCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPT 1074 Query: 429 IAWYFEGEALIQNHRRNVTN-DGT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485 + WY +GE L Q+ R + DG+ + +K++ D+G VA++ G L V Sbjct: 1075 VTWYLKGEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQ 1134 Query: 486 -SPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529 P P R ++ G H T WS N + Sbjct: 1135 KKPFAPEFD-LRPVSLTVEKGSEAVFSAHAFGIPLPTYEWSVNGR 1178 Score = 92.7 bits (220), Expect = 6e-17 Identities = 117/517 (22%), Positives = 201/517 (38%), Gaps = 69/517 (13%) Query: 32 NCRAGGSPSPAIRWYKGGVLVVSDTHRSILP-AGGLFFLRATHGRVHSDAGVYWCEATNS 90 N + G P P ++W+ G+ + D ++ A G + L R D G C A N Sbjct: 5191 NVKVRGLPKPTLQWFLNGIPIKFDDRITLDDMADGNYCLTIRDVR-EEDFGTLKCIAKNE 5249 Query: 91 YGTARS----RNATLHVAVLREEFRLEPE------SKQSAQGDTVVLECLPPRGSPEPNV 140 GT + + H R++ R P ++ GD + +EC +P V Sbjct: 5250 NGTDETVCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVD-ANPTAEV 5308 Query: 141 YWKKNGQTLLFDGDSRM-HLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198 W K+G+ + + + + VDG + I ++D G Y C+A N G E+ AT ++ Sbjct: 5309 EWFKDGKKIEHTAHTEIRNTVDGACRIKIIPFEESDIGVYMCVAVNELGQAETQ-ATYQV 5367 Query: 199 HIKPYL-----------ITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 I ++ I P ED G + C+V P V+W + +PL Sbjct: 5368 EILEHVEEEKRREYAPKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDG----LPL 5423 Query: 247 GR-----VKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP------- 292 ++ +DG+ L +++ D G Y C A N+ G ++ S + V P Sbjct: 5424 RADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKE 5483 Query: 293 ---PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349 P + + G+ C TG P P + W G + R + Sbjct: 5484 GEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQ---LLRNGPRTVIETSP- 5539 Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR---------GKLTVTSDDDRPPPII 400 DG LT+N++ +D C A N G + + GK D+ PP Sbjct: 5540 -DGSCSLTVNESTMSDE-GIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKF 5597 Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-----LVLK 455 S+ ++ + ++ C P P + W +G LI++ R +N+ + L +K Sbjct: 5598 ILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQLRIK 5657 Query: 456 DLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492 + D GTY CVA++ +G + +D + + Sbjct: 5658 NATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGV 5694 Score = 91.5 bits (217), Expect = 1e-16 Identities = 110/474 (23%), Positives = 186/474 (39%), Gaps = 49/474 (10%) Query: 38 SPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97 +P ++WYK + ++H G + A + D Y +N+ G S Sbjct: 4898 APVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSS 4957 Query: 98 NATLHVA--VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155 A V VL+ L+ + Q V L+ + G P+ + W KNGQ L D D Sbjct: 4958 AALTVVKPNVLKIVDGLKDVDVEEPQ--PVELK-VKVEGIPKV-IKWYKNGQELKPDADG 5013 Query: 156 RM--HLVDGG--NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP--- 208 + G +L I ++++D G Y+ + N G S +H+K + P Sbjct: 5014 FKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVYSGSV---VHVKSAKSSEPTSG 5070 Query: 209 -------EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA---GGGNMPLGRVKVLDDGSLR 258 +D + G +T QC + G+P P+V+W + + RV + +LR Sbjct: 5071 ANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLR 5130 Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYD------PPSINLSPNSVNVESGNVARF 312 + + +D G+Y A+N G+ ++ +TV + P + + G+ F Sbjct: 5131 IRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTGAALPGDKKEF 5190 Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372 G P+PT+ W + G P D+ + DG LTI D + D T+ C Sbjct: 5191 NVKVRGLPKPTLQWFLNG-----IPIKFDDRITLDDMADGNYCLTIRDVREEDF-GTLKC 5244 Query: 373 SAVNYAGSSFV-------RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425 A N G+ G + DD R PP ++ +P+ C P Sbjct: 5245 IAKNENGTDETVCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANP 5304 Query: 426 EPIIAWYFEGEALIQNHRRNVTN--DGTLVLK--DLDKSDSGTYTCVASSRHGK 475 + W+ +G+ + + N DG +K ++SD G Y CVA + G+ Sbjct: 5305 TAEVEWFKDGKKIEHTAHTEIRNTVDGACRIKIIPFEESDIGVYMCVAVNELGQ 5358 Score = 90.2 bits (214), Expect = 3e-16 Identities = 118/480 (24%), Positives = 194/480 (40%), Gaps = 35/480 (7%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I+ + TV + + AT N + G P ++WYK G + + + G + L Sbjct: 4400 PEIVSGLIPTTVKQGETATFNVKVKG-PVKQVKWYKNGKEIPNAKAKD--NGDGSYSLEI 4456 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131 + ++ D Y +N G A S +A L V + E + +G VL+ Sbjct: 4457 PNAQL-DDTADYKVVVSNDAGDADS-SAALTVKLPGIAIVKGLEDAEVPKGKKAVLQVET 4514 Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIARNAAG- 187 + E + W KNG+ + D DG N LVI DA DA Y+ + + G Sbjct: 4515 NKKPKE--IKWYKNGKEIT-PSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGN 4571 Query: 188 TRESAIA-TLKIHIK-PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG---GG 242 T +S+ A T+K+ K P +I G ED V GS + + G P V W ++ G Sbjct: 4572 TADSSCALTVKLPAKEPKIIKGLEDQVVSIGSPIKLEIETSGSP-KTVKWYKNGKELPGA 4630 Query: 243 NMPLGRVKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP- 299 +++ +DD L + + ++ D G+Y E N G+ ++SG +TV +P L P Sbjct: 4631 AAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITV-EPKITFLKPL 4689 Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359 ++ G A F+ +P + W G I P ++ D L I Sbjct: 4690 KDQSITEGENAEFSVETNTKPR-IVKWYKNGQE--IKP---NSRFIIEQKTDTKYQLVIK 4743 Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419 + ++D+ +T N AG + +LTV I+ G +Q + + VF Sbjct: 4744 NAVRDDA-DTYKIVLENTAGEAESSAQLTVKKAKAGLCKIV-KGLEDQVVAKGAKMVFEV 4801 Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTN-DGT---LVLKDLDKSDSGTYTCVASSRHGK 475 PE + W + + + D T L++ D D+G YT + GK Sbjct: 4802 KIQGEPED-VRWLRDANVISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGK 4860 Score = 88.2 bits (209), Expect = 1e-15 Identities = 79/284 (27%), Positives = 116/284 (40%), Gaps = 10/284 (3%) Query: 30 TLNCRA--GGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEA 87 TL C+ G P+P ++WY G LV + I A G++ ++ HG G C A Sbjct: 2579 TLECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMK-IHGVTADMTGKIKCVA 2637 Query: 88 TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147 N G + VA + EF +GDT+ L + G PEP V W NG+ Sbjct: 2638 YNKAGEVSTEGPLKVVAPIPVEFETSLCDATCREGDTLKLRAV-LLGEPEPVVSWYVNGK 2696 Query: 148 TLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAG--TRESAIATLKIHIKPYL 204 L + ++H G + I+D +G+ C A N G T E+ + L P Sbjct: 2697 KLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINEYGKATSEATLLVLPRGEPPDF 2756 Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSAGGGNMPLGRVKVLDDGSLRLDNVI 263 + +V A+TG+ V + GDP P + W + N L + D S N Sbjct: 2757 LEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDKTSTLTINSF 2816 Query: 264 LAD--EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305 D GE C+AEN G VS + + Y + S + E Sbjct: 2817 NPDVHVGEIICKAENDAGEVSCTANMITYTSDMFSESESEAQAE 2860 Score = 86.6 bits (205), Expect = 4e-15 Identities = 98/460 (21%), Positives = 167/460 (36%), Gaps = 28/460 (6%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P D V + G P P++ W G V + ++ G + Sbjct: 2365 EVPKFTTNMDDRQVKEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHPNITVTDKDGEHTI 2424 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE--FRLEPESKQSAQGDTVVL 127 + AG CEATN G+ + R+ L V + + F E + +G+ ++ Sbjct: 2425 EIS-AVTPEQAGELSCEATNPVGS-KKRDVQLAVKKVGDAPTFAKNLEDRLITEGELTLM 2482 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ--DARQTDAGRYQCIARNA 185 + P+P + W K+G + DG ++ + G+L + + D GR A + Sbjct: 2483 DAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAESE 2542 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSV--TFQCR--VGGDPLPDVLW----RR 237 G E + + + +P + +A + T +C+ + GDP P V W + Sbjct: 2543 FGVAECSASLGVVKGRPMAKPAFQSDIAPINLTEGDTLECKLLITGDPTPFVKWYIGTQL 2602 Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297 + + + ++++ V G+ C A N G VS G L V P + Sbjct: 2603 VCATEDTEISNANGVY--TMKIHGVTADMTGKIKCVAYNKAGEVSTEGPLKVVAPIPVEF 2660 Query: 298 SPN--SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355 + G+ + G PEP + W V G + K H+ G Sbjct: 2661 ETSLCDATCREGDTLKLRAVLLGEPEPVVSWYVNGKK---LEESQNIKIHSEK---GTYT 2714 Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415 +TI D D +VC A+N G + L V + PP SN + Sbjct: 2715 VTIKDITC-DYSGQVVCEAINEYGKATSEATLLVLPRGE--PPDFLEWLSNVRARTGTKV 2771 Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRN-VTNDGTLVL 454 V P+P + WY + ++ + VT+D T L Sbjct: 2772 VHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDKTSTL 2811 Score = 86.2 bits (204), Expect = 5e-15 Identities = 80/296 (27%), Positives = 130/296 (43%), Gaps = 31/296 (10%) Query: 17 QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAG-GLFFLRATHG 74 +PL+V + L G+P P + W+K + + ++H G G L Sbjct: 3489 RPLEVR--EQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQA 3546 Query: 75 RVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133 R D GVY C+ATN G A++ N + + F + + QG L + Sbjct: 3547 R-GEDVGVYTCKATNEAGEAKTTANMAVQEEIEAPLFVQGLKPYEVEQGKPAEL-VVRVE 3604 Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVD--GGN----LVIQDARQTDAGRYQCIARNAAG 187 G PEP V W K+G + D H+++ G N LVI+D D G+Y C A N AG Sbjct: 3605 GKPEPEVKWFKDGVPIAIDNQ---HVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAG 3661 Query: 188 TRESAIATLKI-----------HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 ++ + LKI +KP I ++ A G +V +C+V + P + + Sbjct: 3662 -KDETVGELKIPKYSFEKQTAEEVKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFF 3720 Query: 237 RSAGGGNMPLG-RVKVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTV 289 ++ + +++VL+DG+++L N D G Y CEA N G + + L + Sbjct: 3721 KNDQPVEIGQHMQLEVLEDGNIKLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKI 3776 Score = 81.0 bits (191), Expect = 2e-13 Identities = 123/534 (23%), Positives = 198/534 (37%), Gaps = 37/534 (6%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 AP ++ + V + A C+ G+ P ++W+K G + D Sbjct: 4017 APGFFKELSAIQVKETETAKFECKVSGT-KPDVKWFKDGTPLKEDKRVHFESTDDGTQRL 4075 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130 D G Y E +N G A S+ V + + QG ++L + Sbjct: 4076 VIEDSKTDDQGNYRIEVSNDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQGTKILLS-V 4134 Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCI-ARNAAG 187 G P+ V W K +T+ +++ V L I+ A +D G Y+ + + ++ Sbjct: 4135 EVEGKPK-TVKWYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFS 4193 Query: 188 TRESAIATL-----KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242 SA T+ KI + P G D G+ + + + G P DV W ++ G Sbjct: 4194 VESSATVTVTKAAEKISL-PSFKKGLADQSVPKGTPLVLEVEIEGKP-KDVKWYKN--GD 4249 Query: 243 NMPLGRVKVLDDGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300 + G+V+ L +G RL + D GEYS A N G + + + V P I Sbjct: 4250 EIKDGKVEDLGNGKYRLTIPDFQEKDVGEYSVTAANEAGEIESKAKVNVSAKPEIVSGLV 4309 Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360 V+ G A F G P + W G I ++D DG L I + Sbjct: 4310 PTTVKQGETATFNVKVKG-PVKGVKWYKNGKE--IPDAKTKDN------GDGSYSLEIPN 4360 Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTV-TSDD--DRPPPIITNGPSNQTLPIKSMAVF 417 D+ + V + N AG + LTV +DD D+ P I +G T+ A F Sbjct: 4361 AQVEDAADYKVVVS-NDAGDADSSAALTVKLADDGKDKVKPEIVSGLIPTTVKQGETATF 4419 Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG--TLVLKDLDKSDSGTYTCVASSRHGK 475 + P + WY G+ I N + DG +L + + D+ Y V S+ G Sbjct: 4420 N-VKVKGPVKQVKWYKNGKE-IPNAKAKDNGDGSYSLEIPNAQLDDTADYKVVVSNDAGD 4477 Query: 476 YVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529 S AL V P I + + + +P + + W +N K Sbjct: 4478 ADSSAALTVKL---PGIAIVKGLEDAEVPKGKKAVLQVETNKKPKEIKWYKNGK 4528 Score = 80.6 bits (190), Expect = 2e-13 Identities = 102/403 (25%), Positives = 167/403 (41%), Gaps = 33/403 (8%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPA-GGL 66 G+AP + D + + ++ + P P I W K GV + SD H I+ G Sbjct: 2460 GDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGS 2519 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA----VLREEFRLEPESKQSAQG 122 L ++ D G +A + +G A +A+L V + + F+ + +G Sbjct: 2520 LKLSILQTKLE-DKGRITIKAESEFGVAEC-SASLGVVKGRPMAKPAFQSDIAPINLTEG 2577 Query: 123 DTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQC 180 DT LEC L G P P V W Q + D+ + +G + I G+ +C Sbjct: 2578 DT--LECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMKIHGVTADMTGKIKC 2635 Query: 181 IARNAAGTRESAIATLKIHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 +A N AG S LK+ + P + T D + G ++ + + G+P P V W Sbjct: 2636 VAYNKAG-EVSTEGPLKV-VAPIPVEFETSLCDATCREGDTLKLRAVLLGEPEPVVSWYV 2693 Query: 238 SAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---D 291 + G +K+ + ++ + ++ G+ CEA N G ++ L V + Sbjct: 2694 N-GKKLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINEYGKATSEATLLVLPRGE 2752 Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 PP ++V +G TG P+P++ W + N+ I+ + D Y T V D Sbjct: 2753 PPDFLEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYIN-NKEIL----NSDLY--TIVTD 2805 Query: 352 GVT-VLTINDTDKNDSRNTIVCSAVNYAGS-SFVRGKLTVTSD 392 T LTIN + + I+C A N AG S +T TSD Sbjct: 2806 DKTSTLTINSFNPDVHVGEIICKAENDAGEVSCTANMITYTSD 2848 Score = 75.8 bits (178), Expect = 7e-12 Identities = 99/334 (29%), Positives = 140/334 (41%), Gaps = 50/334 (14%) Query: 3 DDYVTSGEAPYIIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTH-RSI 60 D + G+AP PL + A+ T C G+P P+I+W K G+ + SD + Sbjct: 5916 DSSIREGKAPGFTT-PLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKME 5974 Query: 61 LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR-------EEFRLE 113 A G L + S+ G + C ATN +GTA S A L + R E E Sbjct: 5975 AAADGTQRLILSDVTFLSE-GYFRCVATNEHGTA-STKAELVIEGDRTIGSRPLPEVNGE 6032 Query: 114 PES----------KQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV--- 160 PE S VV + G P P V W K+GQ ++ DG ++ Sbjct: 6033 PEECKPRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTD 6092 Query: 161 DGG--NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG---------PE 209 + G +LVI +A D G Y A N G+ ++ +L I I+P I P Sbjct: 6093 ERGIHHLVIVNASPDDEGEYSLEATNKLGSAKTE-GSLNI-IRPRHIADADERGGMPFPP 6150 Query: 210 DVVAQTGSS-------VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG----SLR 258 V Q + F C V G P P+V W + G +P GR+K+ G +L Sbjct: 6151 GFVRQLKNKHVFNHMPTIFDCLVVGHPAPEVEWFHN-GKKIVPGGRIKIQSCGGGSHALI 6209 Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292 + + L D GEY A+NS G+ S+S L V P Sbjct: 6210 ILDTTLEDAGEYVATAKNSHGSASSSAVLDVTVP 6243 Score = 75.4 bits (177), Expect = 9e-12 Identities = 74/289 (25%), Positives = 114/289 (39%), Gaps = 23/289 (7%) Query: 217 SSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DG--SLRLDNVILADEGEYSCE 273 SS +V G PLPD+ W + + D DG ++ +D V + D G Y+C Sbjct: 563 SSAKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCM 622 Query: 274 AENSVGAVSASGYLTVYD------PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327 A N G S S + V PP+ + G+V F C G PEP + W Sbjct: 623 ATNEYGQASTSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWL 682 Query: 328 VEGNRTIIFPGMSRDKYHATAVFDGVTV-LTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386 V+ R + +DG T L I D +D+ N GS + + Sbjct: 683 VDDQPL-------RPSHDFRLQYDGQTAKLEIRDAQPDDT-GVYTVKIQNEFGSIESKAE 734 Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT--PEPIIAWYFEGEALIQNHR- 443 L V +D D+ + + + ++ T P P I W+ G+ L ++ + Sbjct: 735 LFVQADPDKNHVAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKV 794 Query: 444 RNVTNDG--TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490 + ++ DG L +KD+ + G TC S+R G G L V P P Sbjct: 795 KFISEDGICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPAP 843 Score = 74.5 bits (175), Expect = 2e-11 Identities = 119/491 (24%), Positives = 192/491 (39%), Gaps = 40/491 (8%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL--PAGGLFFL 69 P II+ D V+ P L GSP ++WYK G + ++I ++ Sbjct: 4588 PKIIKGLEDQVVSIGSPIKLEIETSGSPK-TVKWYKNGKELPGAAAKTIKIQKIDDNKYV 4646 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS-AQGDTVVLE 128 V D G Y E N G+A N++ + V + L+P QS +G+ E Sbjct: 4647 LEIPSSVVEDTGDYKVEVANEAGSA---NSSGKITVEPKITFLKPLKDQSITEGENA--E 4701 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN----LVIQDARQTDAGRYQCIARN 184 + V W KNGQ + +SR + + LVI++A + DA Y+ + N Sbjct: 4702 FSVETNTKPRIVKWYKNGQEI--KPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLEN 4759 Query: 185 AAGTRESAIATLKIHIKPYL---ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241 AG ES+ K L + G ED V G+ + F+ ++ G+P DV W R A Sbjct: 4760 TAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKIQGEP-EDVRWLRDANV 4818 Query: 242 GNMPLGRV-KVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298 + + + +DD + RL + L D GEY+ E N G + V + P I Sbjct: 4819 ISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGKAKSDAKGEVDEKPEIVRG 4878 Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358 ++ + G+ F + P + W N I P A + L I Sbjct: 4879 LENIEIPEGDDDVFKVEVSA-PVRQVKW--YKNDQEIKP---NSHLEAKKIGPKKYELAI 4932 Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418 N +D + V + N AG LTV + I +G + + Sbjct: 4933 NRAQLDDGADYKVVLS-NAAGDCDSSAALTVVKPNVLK---IVDGLKDVDVEEPQPVELK 4988 Query: 419 CTAICTPEPIIAWYFEGEAL------IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472 P+ +I WY G+ L + + + + +L + KSD G Y V + Sbjct: 4989 VKVEGIPK-VIKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGND 5047 Query: 473 HGKYVWSGALL 483 G+ V+SG+++ Sbjct: 5048 KGE-VYSGSVV 5057 Score = 72.5 bits (170), Expect = 6e-11 Identities = 87/393 (22%), Positives = 159/393 (40%), Gaps = 30/393 (7%) Query: 105 VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN 164 V+ +F + + ++ +G + V EC+ P + W K+G+ + R+ G Sbjct: 2884 VMAPKFITKIKDTKAKKGHSAVFECVVP-DTKGVCCKWLKDGKEIELIARIRVQTRTGPE 2942 Query: 165 ------LVIQDARQTDAGRYQCIARNAAG--TRESAIATLKIHIK------PYLITGPED 210 LV+ + DAG+Y CI N AG T E+ + ++ K P I +D Sbjct: 2943 GHITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKKAPEFIVALQD 3002 Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGE 269 +T V +C+V G+P P V W V+ ++ + + + L+ +G+ Sbjct: 3003 KTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVEGVERVTITSSELSHQGK 3062 Query: 270 YSCEAENSVGAVSASGYLTVY-DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328 Y+C AEN+ G +LTV + P + + G +C+ G P+P + + Sbjct: 3063 YTCIAENTEGTSKTEAFLTVQGEAPVFTKELQNKELSIGEKLVLSCSVKGSPQPHVDFYS 3122 Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVT--VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386 T + ++ A T + I+ K D + A N G++ K Sbjct: 3123 FSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDI-VSYKAIATNSIGTATSTSK 3181 Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ--NH-- 442 +T + P+ G ++ K + P + W+ + + + + NH Sbjct: 3182 ITTKVE----APVFEQGLKKTSVKEKEEIKME-VKVGGSAPDVEWFKDDKPVSEDGNHEM 3236 Query: 443 RRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 ++N T TLV+K +D+G YT AS+ G Sbjct: 3237 KKNPETGVFTLVVKQAATTDAGKYTAKASNPAG 3269 Score = 72.5 bits (170), Expect = 6e-11 Identities = 119/493 (24%), Positives = 193/493 (39%), Gaps = 42/493 (8%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I+ + TV + + AT N + G P ++WYK G + + G + L Sbjct: 4302 PEIVSGLVPTTVKQGETATFNVKVKG-PVKGVKWYKNGKEIPDAKTKD--NGDGSYSLEI 4358 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSA------QGDT 124 + +V DA Y +N G A S +A L V + + + +++PE QG+T Sbjct: 4359 PNAQVE-DAADYKVVVSNDAGDADS-SAALTVKLADDGKDKVKPEIVSGLIPTTVKQGET 4416 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 + +G P V W KNG+ + + ++ + +L I +A+ D Y+ + N Sbjct: 4417 ATFN-VKVKG-PVKQVKWYKNGKEIP-NAKAKDNGDGSYSLEIPNAQLDDTADYKVVVSN 4473 Query: 185 AAGTRESAIA-TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 AG +S+ A T+K+ ++ G ED G Q P ++ W ++ G Sbjct: 4474 DAGDADSSAALTVKLP-GIAIVKGLEDAEVPKGKKAVLQVETNKKP-KEIKWYKN-GKEI 4530 Query: 244 MPLGRVKVLDDGSLRLDNVILA----DEGEYSCEAENSVG-AVSASGYLTVYDP---PSI 295 P + + DG + VI D EY + G +S LTV P P I Sbjct: 4531 TPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVKLPAKEPKI 4590 Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355 V G+ + +G P+ T+ W G PG + + D V Sbjct: 4591 IKGLEDQVVSIGSPIKLEIETSGSPK-TVKWYKNGKE---LPGAAAKTIKIQKIDDNKYV 4646 Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415 L I + D+ + V N AGS+ GK+TV P +Q++ A Sbjct: 4647 LEIPSSVVEDTGDYKV-EVANEAGSANSSGKITV-----EPKITFLKPLKDQSITEGENA 4700 Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHR----RNVTNDGTLVLKDLDKSDSGTYTCVASS 471 F P I+ WY G+ + N R + LV+K+ + D+ TY V + Sbjct: 4701 EFSVETNTKPR-IVKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLEN 4759 Query: 472 RHGKYVWSGALLV 484 G+ S L V Sbjct: 4760 TAGEAESSAQLTV 4772 Score = 64.5 bits (150), Expect = 2e-08 Identities = 54/207 (26%), Positives = 90/207 (43%), Gaps = 15/207 (7%) Query: 115 ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG---QTLLFDGDSRMHLVDGGN--LVIQD 169 E + A+ DT+ + L G P+P++ WK G T +++ G L I Sbjct: 6417 EKRYCAENDTLTI-VLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITG 6475 Query: 170 ARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP 229 + + G+YQC A+N G + I + + +P I + + + RV G+P Sbjct: 6476 FSKENVGQYQCFAKNDYGDAQQNIM-VDLATRPNFIQPLVNKTFSSAQPMRMDVRVDGEP 6534 Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDG----SLRLDNVILADEGEYSCEAENSVGAVSASG 285 P++ W + + R+K + DG SL +++ + D G YSC A N G + S Sbjct: 6535 FPELKWMKE-WRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSC 6593 Query: 286 YLTVY---DPPSINLSPNSVNVESGNV 309 +TV D + L V +ES V Sbjct: 6594 TVTVEAEGDYNDVELPRRRVTIESRRV 6620 Score = 64.1 bits (149), Expect = 2e-08 Identities = 94/423 (22%), Positives = 157/423 (37%), Gaps = 33/423 (7%) Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67 S AP ++ D TV + A G+P+P + W+ G + + + A Sbjct: 942 SRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFINGHKMDQGSPGVKIEAHNHD 1001 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPE-------SKQSA 120 + AG C A N+ G ++ + VL E + +P K Sbjct: 1002 HKLTIDSAQY--AGTVLCRAENAVGRFETK---ARLVVLAPEKQKKPPKFVEILVDKTET 1056 Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQ 179 +TVV E + G P+P V W G+ L + DG + I++ + DAG + Sbjct: 1057 VDNTVVFE-VRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIR 1115 Query: 180 CIARNAAGTRESAIATLKIHIKPY---LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 +A N+ G+ E+ A L + KP+ P + + GS F G PLP W Sbjct: 1116 AVATNSEGSDETK-AKLTVQKKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWS 1174 Query: 237 RSA-----GGGNMPLGRVKVLDDGS--LRLDNVILADEGEY---SCEAENSVGAVSASGY 286 + G + R + DG+ L +D E + S AEN++GA Sbjct: 1175 VNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISVVAENTLGAEETGAQ 1234 Query: 287 LTVYDPPSINLSPNSVNVESGNVARFTC--TATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344 LT+ +P ++ ++ S V + PE T ++E + T + Sbjct: 1235 LTI-EPKKESVVVEKQDLSSSEVQKEIAQQVKEASPEATTTITMETSLTST-KTTTMSTT 1292 Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404 T+ GVTV T +++ + I + S K+ V S D + P Sbjct: 1293 EVTSTVGGVTVET-KESESESATTVIGGGSGGVTEGSISVSKIEVVSKTDSQTDVREGTP 1351 Query: 405 SNQ 407 + Sbjct: 1352 KRR 1354 Score = 61.7 bits (143), Expect = 1e-07 Identities = 66/257 (25%), Positives = 93/257 (36%), Gaps = 16/257 (6%) Query: 277 SVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF 336 +VG ++S T P S V A C G P P + W+ EG Sbjct: 3801 TVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEV--- 3857 Query: 337 PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD--- 393 MS + A DG LT ++ + D+ C A N GS++ G + VT + Sbjct: 3858 -EMSA-RVRAEHKDDGTLTLTFDNVTQADA-GEYRCEAENEYGSAWTEGPIIVTLEGAPK 3914 Query: 394 -DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN--DG 450 D P + + AV P+P + WY GE L + R + N DG Sbjct: 3915 IDGEAPDFLQPVKPAVVTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDG 3974 Query: 451 T--LVLKDLDKSDSGTYTCVASSRHGKYVWSG-ALLVDSPINPNIHFFRAADVSSLPGPP 507 T L + + D Y C AS+ G VWS L V P FF+ + Sbjct: 3975 TQRLTVTNAKLDDMDEYRCEASNEFGD-VWSDVTLTVKEPAQVAPGFFKELSAIQVKETE 4033 Query: 508 TKPITHNVTDTSVTLSW 524 T V+ T + W Sbjct: 4034 TAKFECKVSGTKPDVKW 4050 Score = 60.9 bits (141), Expect = 2e-07 Identities = 54/215 (25%), Positives = 86/215 (40%), Gaps = 25/215 (11%) Query: 388 TVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT 447 T +DD PI T + L A+F C +P P + W F+G+ L N R + Sbjct: 7518 TKKNDDGTFAPIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIE 7577 Query: 448 NDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLP 504 D L+L D G Y C A + +G S L+ + + S P Sbjct: 7578 QDNNVARLILNHAAPYDLGEYVCTAINEYGTDKSSCRLI-------------SGETPSRP 7624 Query: 505 GPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIA 564 G P ++ +DT + + W G + + G + R ++G N + W+ ++ Sbjct: 7625 GRPEAELS---SDTEIFIQWEAPE--GPTYLEGITYRLEYR--VAGPND--HGDPWITVS 7675 Query: 565 RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599 ++ +VK L P Y F V +N GL PS Sbjct: 7676 EKIDDESVIVKHLSPLGIYQFRVTAQNGFGLGLPS 7710 Score = 60.5 bits (140), Expect = 3e-07 Identities = 89/376 (23%), Positives = 149/376 (39%), Gaps = 27/376 (7%) Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228 D +G +A NAAG+ E+ LK+ P PE VT V D Sbjct: 1944 DTTMFGSGTVSVVASNAAGSVETK-TELKVLETPKETKKPEFTDKLRDMEVTKGDTVQMD 2002 Query: 229 --PLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA---DEGEYSCEAENSVGAVSA 283 L L++ G + G+ V ++I+ D G+ + EA N VG+ + Sbjct: 2003 VIALHSPLYKWYQNGNLLEDGKNGVTIKNEENKSSLIIPNAQDSGKITVEASNEVGSSES 2062 Query: 284 SGYLTVYDP---PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340 S LTV P P + P SV ++ A F T +G P PT+ W++ N I+ Sbjct: 2063 SAQLTVNPPSTTPIVVDGPKSVTIKETETAEFKATISGFPAPTVKWTI--NEKIV----E 2116 Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP--PP 398 + T + V L I++ K + T+ +A N AG + L V + P Sbjct: 2117 ESRTITTIKTEDVYTLKISNA-KIEQTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKS 2175 Query: 399 IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN--DGT--LVL 454 +T+ +++ P++ +P ++W G+ L ++ V + DGT + + Sbjct: 2176 QLTDKVADEGEPLRWNLELDGP---SPGTEVSWLLNGQPLTKSDTVQVVDHGDGTYHVTI 2232 Query: 455 KDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHN 514 + SGT T A + G+ S + V+ N F +A + + Sbjct: 2233 AEAKPEMSGTLTAKAKNAAGECETSAKVTVNGG-NKKPEFVQAPQNHETTLEESVKFSAI 2291 Query: 515 VTDTSV-TLSWSQNNK 529 VT + ++W NNK Sbjct: 2292 VTGKPMPNVTWYLNNK 2307 Score = 51.6 bits (118), Expect = 1e-04 Identities = 47/171 (27%), Positives = 75/171 (43%), Gaps = 12/171 (7%) Query: 24 ARHQPATLNCRAGGSPSPAIRW-YKG-GVLVVSDTHR-SILPAGGLFFLRATHGRVHSDA 80 A + T+ G P P I+W ++G + S T + + GG A G + Sbjct: 6422 AENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSKENV 6481 Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140 G Y C A N YG A+ +N + +A R F ++P ++ + + G P P + Sbjct: 6482 GQYQCFAKNDYGDAQ-QNIMVDLAT-RPNF-IQPLVNKTFSSAQPMRMDVRVDGEPFPEL 6538 Query: 141 YWKKNGQTLLFDGDSRMHLVDGG----NLVIQDARQTDAGRYQCIARNAAG 187 W K + ++ SR+ V G +L+I D D+G Y C+A N AG Sbjct: 6539 KWMKEWRPIV--ESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAG 6587 Score = 48.4 bits (110), Expect = 0.001 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 1/86 (1%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 AP + DV + ++QPA C SP+P + W G ++ S+ +I + L Sbjct: 7527 APIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIEQDNNVARLI 7586 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARS 96 H + D G Y C A N YGT +S Sbjct: 7587 LNHAAPY-DLGEYVCTAINEYGTDKS 7611 Score = 39.9 bits (89), Expect = 0.41 Identities = 21/83 (25%), Positives = 36/83 (43%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I+ ++ T + QP ++ R G P P ++W K +V + + G Sbjct: 6507 PNFIQPLVNKTFSSAQPMRMDVRVDGEPFPELKWMKEWRPIVESSRIKFVQDGPYLCSLI 6566 Query: 72 THGRVHSDAGVYWCEATNSYGTA 94 + + D+G+Y C A N G A Sbjct: 6567 INDPMWRDSGIYSCVAVNDAGQA 6589 >UniRef50_Q13308 Cluster: Tyrosine-protein kinase-like 7 precursor; n=29; Tetrapoda|Rep: Tyrosine-protein kinase-like 7 precursor - Homo sapiens (Human) Length = 1070 Score = 146 bits (354), Expect = 3e-33 Identities = 127/486 (26%), Positives = 209/486 (43%), Gaps = 37/486 (7%) Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT------HRSILPAGGLF 67 ++ P DV VAR++ A +C+ P P+++W +++ R+ + A G Sbjct: 227 VVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSL 286 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127 L R +AG+Y C G ATLH+A + + EP + + V Sbjct: 287 LLTQVRPR---NAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVT- 342 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 CLPP+G PEP+V+W+ G L G R++ G LV+ + ++DAG Y C A N AG Sbjct: 343 -CLPPKGLPEPSVWWEHAGVRLPTHG--RVYQ-KGHELVLANIAESDAGVYTCHAANLAG 398 Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247 R + + + P + P+D + G C P P V+W R+ + Sbjct: 399 QRRQDV-NITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISED-S 456 Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN-VES 306 R +V +G+LR+++V + D Y C + G++ A + V + P +E Sbjct: 457 RFEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEF 516 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 A C+ATGR +PT+ W G S ++ V D L ++D+ Sbjct: 517 DKEATVPCSATGREKPTIKWERAD-------GSSLPEW----VTDNAGTLHFARVTRDDA 565 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426 N ++ G +LTV P T+ A+ C A P+ Sbjct: 566 GNYTCIASNGPQGQIRAHVQLTVAVFIT-----FKVEPERTTVYQGHTALLQCEAQGDPK 620 Query: 427 PIIAWYFEGEALIQNH---RRNVTNDGTLVLKDLDKSDSGTYTCVA-SSRHGKYVWSGAL 482 P+I W + L R ++ +G+LV+ D+ DSG YTC+A +S + K+ + Sbjct: 621 PLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLY 680 Query: 483 LVDSPI 488 +VD P+ Sbjct: 681 VVDKPV 686 Score = 112 bits (270), Expect = 5e-23 Identities = 106/373 (28%), Positives = 155/373 (41%), Gaps = 28/373 (7%) Query: 37 GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96 G P P++ W GV + TH + G L SDAGVY C A N G R Sbjct: 348 GLPEPSVWWEHAGVRL--PTHGRVYQKGHELVLANI---AESDAGVYTCHAANLAGQRR- 401 Query: 97 RNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSR 156 ++ + VA + + +P+ Q +G L+CL + +P+P V W +N +L DSR Sbjct: 402 QDVNITVATVPSWLK-KPQDSQLEEGKPGYLDCLT-QATPKPTVVWYRN--QMLISEDSR 457 Query: 157 MHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE-DVVAQT 215 + G L I D Y+C++ AG+ E A A +++ K P+ + Sbjct: 458 FEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIE-AQARVQVLEKLKFTPPPQPQQCMEF 516 Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGEYSCEA 274 T C G P + W R A G ++P V D+ G+L V D G Y+C A Sbjct: 517 DKEATVPCSATGREKPTIKWER-ADGSSLPEW---VTDNAGTLHFARVTRDDAGNYTCIA 572 Query: 275 ENSV-GAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRT 333 N G + A LTV + + P V G+ A C A G P+P + W +G Sbjct: 573 SNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQW--KGKDR 630 Query: 334 IIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393 I+ P + H +F + L I+D DS C A N L V Sbjct: 631 ILDPTKLGPRMH---IFQNGS-LVIHDVAPEDS-GRYTCIAGNSCNIKHTEAPLYVV--- 682 Query: 394 DRPPPIITNGPSN 406 D+P P + GP + Sbjct: 683 DKPVPEESEGPGS 695 Score = 108 bits (260), Expect = 8e-22 Identities = 127/474 (26%), Positives = 191/474 (40%), Gaps = 41/474 (8%) Query: 12 PYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFL 69 P +++ P + + TL C G P P +W++ G L ++ ++ L Sbjct: 128 PVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTL 187 Query: 70 RATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFR---LEPESKQSAQGDTV 125 R G HS G+Y C A +++G A S+N TL +A E F L P+ A+ + Sbjct: 188 RPA-GPEHS--GLYSCCAHSAFGQACSSQNFTLSIA--DESFARVVLAPQDVVVARYEEA 242 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL-----VDGGNLVIQDARQTDAGRYQC 180 + C P P++ W +T + + HL G+L++ R +AG Y+C Sbjct: 243 MFHC-QFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRC 301 Query: 181 IARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239 I + G ATL + I+ + P A + VT G P P V W + Sbjct: 302 IGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTC-LPPKGLPEPSVWWEHA- 359 Query: 240 GGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298 G +P GRV L L N+ +D G Y+C A N G +TV PS Sbjct: 360 -GVRLPTHGRV-YQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKK 417 Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358 P +E G C P+PT+ W N+ +I S D VF T L I Sbjct: 418 PQDSQLEEGKPGYLDCLTQATPKPTVVW--YRNQMLI----SEDS--RFEVFKNGT-LRI 468 Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418 N + D C + AGS + ++ V PP Q + A P Sbjct: 469 NSVEVYDG-TWYRCMSSTPAGSIEAQARVQVLEKLKFTPP----PQPQQCMEFDKEATVP 523 Query: 419 CTAICTPEPIIAW-YFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471 C+A +P I W +G +L + N GTL + + D+G YTC+AS+ Sbjct: 524 CSATGREKPTIKWERADGSSLPE---WVTDNAGTLHFARVTRDDAGNYTCIASN 574 Score = 101 bits (243), Expect = 9e-20 Identities = 126/479 (26%), Positives = 187/479 (39%), Gaps = 44/479 (9%) Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73 I+QP + + A L C +P P + W G V DT R L F A Sbjct: 35 IKQPSSQDALQGRRALLRCEVE-APGPVHVYWLLDGA-PVQDTERRFAQGSSLSF--AAV 90 Query: 74 GRVHSDAGVYWCEATNSYG--TARSRNATLHVAVLREE--FRLEPESKQSAQGDT-VVLE 128 R+ D+G + C A + ARS NA+ ++ + P S+ Q T V L Sbjct: 91 DRLQ-DSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 149 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAA 186 C G P P W ++G T L DG S H V NL ++ A +G Y C A +A Sbjct: 150 CHID-GHPRPTYQWFRDG-TPLSDGQSN-HTVSSKERNLTLRPAGPEHSGLYSCCAHSAF 206 Query: 187 GTR-ESAIATLKIHIKPY--LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSA 239 G S TL I + + ++ P+DVV F C+ P P + W Sbjct: 207 GQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPI 266 Query: 240 GGGNMP--LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSIN 296 + P L R V +GSL L V + G Y C + G + L + + + Sbjct: 267 TNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMP 326 Query: 297 LSPNSVNVESGNVARFTCTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355 L V +G+ R TC G PEP+++W G R P R V+ Sbjct: 327 LFEPRV-FTAGSEERVTCLPPKGLPEPSVWWEHAGVR---LPTHGR-------VYQKGHE 375 Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415 L + + ++D+ C A N AG +TV + P P + L Sbjct: 376 LVLANIAESDA-GVYTCHAANLAGQRRQDVNITVAT-----VPSWLKKPQDSQLEEGKPG 429 Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 C TP+P + WY + ++ R V +GTL + ++ D Y C++S+ G Sbjct: 430 YLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCMSSTPAG 488 Score = 92.3 bits (219), Expect = 7e-17 Identities = 78/296 (26%), Positives = 119/296 (40%), Gaps = 18/296 (6%) Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62 D +T P +++P D + +P L+C +P P + WY+ +L+ D+ + Sbjct: 403 DVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFK 462 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQ 121 G L R V+ D Y C ++ G S A V VL + +F P+ +Q + Sbjct: 463 NGTL---RINSVEVY-DGTWYRCMSSTPAG---SIEAQARVQVLEKLKFTPPPQPQQCME 515 Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV--DGGNLVIQDARQTDAGRYQ 179 D G +P + W++ DG S V + G L + DAG Y Sbjct: 516 FDKEATVPCSATGREKPTIKWERA------DGSSLPEWVTDNAGTLHFARVTRDDAGNYT 569 Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RS 238 CIA N + A L + + PE G + QC GDP P + W+ + Sbjct: 570 CIASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKD 629 Query: 239 AGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293 LG R+ + +GSL + +V D G Y+C A NS L V D P Sbjct: 630 RILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKP 685 Score = 83.0 bits (196), Expect = 4e-14 Identities = 97/384 (25%), Positives = 151/384 (39%), Gaps = 36/384 (9%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169 F +P S+ + QG +L C P +VYW +G + D+ G +L Sbjct: 34 FIKQPSSQDALQGRRALLRCEVEAPGPV-HVYWLLDGAPVQ---DTERRFAQGSSLSFAA 89 Query: 170 A-RQTDAGRYQCIARNAAGTRESAIATLKIHIK-----PYLITGP-EDVVAQTGSSVTFQ 222 R D+G +QC+AR+ E+ A +IK P ++ P + Q + VT + Sbjct: 90 VDRLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 149 Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVG-A 280 C + G P P W R + V + +L L G YSC A ++ G A Sbjct: 150 CHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQA 209 Query: 281 VSASGY-LTVYDPP--SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337 S+ + L++ D + L+P V V A F C + +P P++ W E I Sbjct: 210 CSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNR 269 Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV-RGKLTVTSDDDRP 396 AT +G +LT + + C G + L + +D P Sbjct: 270 SRPPHLRRATVFANGSLLLT---QVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMP 326 Query: 397 ---PPIITNGPSNQT--LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT 451 P + T G + LP K + PEP + W G L H R Sbjct: 327 LFEPRVFTAGSEERVTCLPPKGL----------PEPSVWWEHAGVRL-PTHGRVYQKGHE 375 Query: 452 LVLKDLDKSDSGTYTCVASSRHGK 475 LVL ++ +SD+G YTC A++ G+ Sbjct: 376 LVLANIAESDAGVYTCHAANLAGQ 399 >UniRef50_O00533 Cluster: Neural cell adhesion molecule L1-like protein precursor; n=25; Euteleostomi|Rep: Neural cell adhesion molecule L1-like protein precursor - Homo sapiens (Human) Length = 1208 Score = 146 bits (354), Expect = 3e-33 Identities = 120/485 (24%), Positives = 200/485 (41%), Gaps = 34/485 (7%) Query: 10 EAPYIIEQP-LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68 + P II+Q + V + + C A G+P P W K G HR I F Sbjct: 33 QVPTIIKQSKVQVAFPFDEYFQIECEAKGNPEPTFSWTKDGNPFYFTDHRIIPSNNSGTF 92 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128 G + G Y C A+N G A S V + + + + + + +GD +VL Sbjct: 93 RIPNEGHISHFQGKYRCFASNKLGIAMSEEIEFIVPSVPKFPKEKIDPLEVEEGDPIVLP 152 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIARNAAG 187 C PP+G P ++YW N + + D R+++ G+L + + D+ Y C A Sbjct: 153 CNPPKGLPPLHIYWM-NIELEHIEQDERVYMSQKGDLYFANVEEKDSRNDYCCFAAFPRL 211 Query: 188 TRESAIATLKIHI---------KPYLITGPEDVVAQT------GSSVTFQCRVGGDPLPD 232 +K+ + KP L+ P + +++ G + +C G P P Sbjct: 212 RTIVQKMPMKLTVNSSNSIKQRKPKLLLPPTESGSESSITILKGEILLLECFAEGLPTPQ 271 Query: 233 VLWRRSAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291 V W + GG++P GR + G +L+++NV D+G Y C A N +G + ++ V + Sbjct: 272 VDWNKI--GGDLPKGREAKENYGKTLKIENVSYQDKGNYRCTASNFLGTATHDFHVIVEE 329 Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 PP P S +G+ C A G P+PT+ W V G+ P + VF Sbjct: 330 PPRWTKKPQSAVYSTGSNGILLCEAEGEPQPTIKWRVNGSPVDNHP------FAGDVVFP 383 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411 ++ + N + C A N G+ + V D P I T N + Sbjct: 384 --REISFTNLQPNHTA-VYQCEASNVHGTILANANIDVV---DVRPLIQTKDGENYATVV 437 Query: 412 KSMAVFPCTAICTPEPIIAWY-FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470 A C +PE +++W E ++ R ++ +GTL + + D+G+Y+C Sbjct: 438 GYSAFLHCEFFASPEAVVSWQKVEEVKPLEGRRYHIYENGTLQINRTTEEDAGSYSCWVE 497 Query: 471 SRHGK 475 + GK Sbjct: 498 NAIGK 502 Score = 84.2 bits (199), Expect = 2e-14 Identities = 83/301 (27%), Positives = 124/301 (41%), Gaps = 20/301 (6%) Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62 D +V E P ++P + L C A G P P I+W G V D H Sbjct: 322 DFHVIVEEPPRWTKKPQSAVYSTGSNGILLCEAEGEPQPTIKWRVNGSPV--DNHPF--- 376 Query: 63 AGGLFFLR--ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL-EPESKQS 119 AG + F R + + VY CEA+N +GT + NA + V +R + + E+ + Sbjct: 377 AGDVVFPREISFTNLQPNHTAVYQCEASNVHGTILA-NANIDVVDVRPLIQTKDGENYAT 435 Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179 G + L C SPE V W+K + +G R H+ + G L I + DAG Y Sbjct: 436 VVGYSAFLHC-EFFASPEAVVSWQKVEEVKPLEG-RRYHIYENGTLQINRTTEEDAGSYS 493 Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP-LPDVL---W 235 C NA G + + A L I L P++ + C D L L W Sbjct: 494 CWVENAIG-KTAVTANLDIRNATKLRVSPKNPRIPKLHMLELHCESKCDSHLKHSLKLSW 552 Query: 236 RRSAGG---GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292 + GR+ ++D +L + NV L D+G Y C A ++ + + +TV D Sbjct: 553 SKDGEAFEINGTEDGRI-IIDGANLTISNVTLEDQGIYCCSAHTALDSAADITQVTVLDV 611 Query: 293 P 293 P Sbjct: 612 P 612 Score = 82.6 bits (195), Expect = 6e-14 Identities = 69/299 (23%), Positives = 119/299 (39%), Gaps = 17/299 (5%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80 +T+ + + L C A G P+P + W K G D + + D Sbjct: 250 ITILKGEILLLECFAEGLPTPQVDWNKIG----GDLPKGREAKENYGKTLKIENVSYQDK 305 Query: 81 GVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139 G Y C A+N GTA HV V + +P+S + G +L C G P+P Sbjct: 306 GNYRCTASNFLGTATH---DFHVIVEEPPRWTKKPQSAVYSTGSNGILLC-EAEGEPQPT 361 Query: 140 VYWKKNGQTL---LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196 + W+ NG + F GD +V + + + YQC A N GT + Sbjct: 362 IKWRVNGSPVDNHPFAGD----VVFPREISFTNLQPNHTAVYQCEASNVHGTILANANID 417 Query: 197 KIHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255 + ++P + T E+ G S C P V W++ + R + ++G Sbjct: 418 VVDVRPLIQTKDGENYATVVGYSAFLHCEFFASPEAVVSWQKVEEVKPLEGRRYHIYENG 477 Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314 +L+++ D G YSC EN++G + + L + + + +SP + + ++ C Sbjct: 478 TLQINRTTEEDAGSYSCWVENAIGKTAVTANLDIRNATKLRVSPKNPRIPKLHMLELHC 536 Score = 46.0 bits (104), Expect = 0.006 Identities = 65/283 (22%), Positives = 107/283 (37%), Gaps = 25/283 (8%) Query: 222 QCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNV--ILADEGEYSCEAENSV 278 +C G+P P W + R+ ++ G+ R+ N I +G+Y C A N + Sbjct: 56 ECEAKGNPEPTFSWTKDGNPFYFTDHRIIPSNNSGTFRIPNEGHISHFQGKYRCFASNKL 115 Query: 279 G-AVSASGYLTVYDPPSINLSP-NSVNVESGNVARFTCTAT-GRPEPTMFWSVEGNRTII 335 G A+S V P + + VE G+ C G P ++W I Sbjct: 116 GIAMSEEIEFIVPSVPKFPKEKIDPLEVEEGDPIVLPCNPPKGLPPLHIYWM-----NIE 170 Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG---KLTVTSD 392 + +D+ L + ++ DSRN C A + V+ KLTV S Sbjct: 171 LEHIEQDE---RVYMSQKGDLYFANVEEKDSRNDYCCFAAFPRLRTIVQKMPMKLTVNSS 227 Query: 393 DD----RP----PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR 444 + +P PP + S+ T+ + + C A P P + W G L + Sbjct: 228 NSIKQRKPKLLLPPTESGSESSITILKGEILLLECFAEGLPTPQVDWNKIGGDLPKGREA 287 Query: 445 NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 TL ++++ D G Y C AS+ G ++V+ P Sbjct: 288 KENYGKTLKIENVSYQDKGNYRCTASNFLGTATHDFHVIVEEP 330 Score = 39.9 bits (89), Expect = 0.41 Identities = 44/168 (26%), Positives = 64/168 (38%), Gaps = 11/168 (6%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSN-SRVAQTLDDVPDGPPINIEMFILNTTTVHLKW 752 I L + +Y+F +I + +PS S +T PD P NI + + +KW Sbjct: 673 ILPLAPFVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAPDRNPQNIRVQASQPKEMIIKW 732 Query: 753 SPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAA 812 P + QNG G V W P + TV T +MT Y V++ A Sbjct: 733 EPLKSMEQNG--PGLEYRVTW--KPQGAPVEWEEETVTNHTLRVMTPAVY-APYDVKVQA 787 Query: 813 ETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETW 860 +G GP Q V + G D P+ V ++ V TW Sbjct: 788 INQLGSGPDPQSV-----TLYSGEDYPDTAPVIHGVDVINSTLVKVTW 830 >UniRef50_Q4SR20 Cluster: Chromosome 11 SCAF14528, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 11 SCAF14528, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 786 Score = 145 bits (352), Expect = 6e-33 Identities = 139/510 (27%), Positives = 214/510 (41%), Gaps = 60/510 (11%) Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT 173 PES +A+ V LEC G+P P + W++ + F +M L I + +Q Sbjct: 83 PESVPAAKESAVKLECFA-LGNPVPEISWRRTSG-IPFPSKVKMKN-SNAVLEIPNFQQE 139 Query: 174 DAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233 DAG Y+C+A N G + +A L H KP+ + D +++ ++C+ G P P Sbjct: 140 DAGTYECVAENRRG-KNAARGRLSFHAKPHWLQTMADTALSIEANLFWECKANGKPKPSY 198 Query: 234 LWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-DP 292 W ++ G GR+++ D+G+L + + L+D G Y C AEN G + +S L V P Sbjct: 199 SWLKN-GEQVAAEGRIQI-DNGALSIAVLNLSDSGMYQCVAENKHGIIYSSAQLMVLASP 256 Query: 293 PSINLSPNS--VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350 P+ + SP + SG+ C P W +GN I P R + Sbjct: 257 PNFSKSPLKALLKARSGSEVTLECKPEAWPPAISLWK-KGNE--ILPRTERIN-----LL 308 Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410 T+ N T ++ T C A N G++ GKL +T P IT P+N + Sbjct: 309 PNGTIKIANATRQDAGSYT--CIAKNQFGTASTTGKLLITE-----PTRITMRPTNTEII 361 Query: 411 IKSMAVFPCTAICTP--EPIIAWYFEGEAL-IQ---NHRRNVTND--GTLVLKDLDKSDS 462 + AV PC P + +W F G+ + Q NH V G L+++++ S Sbjct: 362 VGESAVLPCQIAFDPALDVSFSWAFNGQLIDFQRDGNHFERVGGSVSGDLMIRNIQLSHG 421 Query: 463 GTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTL 522 G Y C+ + S L+V P PGPP K +TD++ L Sbjct: 422 GKYVCLIDTDVESLSTSAILVVKGP----------------PGPPDKVTVEEITDSTAQL 465 Query: 523 SWSQNNKIGSSSILGYQVEVFSRETL---SGNNTPRNSRGWVVIARRVHQTHYVVKSLIP 579 SW+ G S I GY ++ + T+ + + P G ++ A V L Sbjct: 466 SWTPGRDNG-SPITGYIIQARTPFTVGWQAVDTVPEVINGNMLTA--------TVVGLNA 516 Query: 580 GITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 + Y F V N+ GL PSP S D Sbjct: 517 WVEYEFRVVARNAVGLGEPSPASAKTRTED 546 Score = 107 bits (257), Expect = 2e-21 Identities = 88/335 (26%), Positives = 142/335 (42%), Gaps = 19/335 (5%) Query: 2 SDDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSI 60 SD + E + P V A+ L C A G+P P I W + G+ S Sbjct: 67 SDGVMGEYEPKIEVHFPESVPAAKESAVKLECFALGNPVPEISWRRTSGIPFPSKVKMKN 126 Query: 61 LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA 120 A L + + DAG Y C A N G +R L + ++ S Sbjct: 127 SNA----VLEIPNFQ-QEDAGTYECVAENRRGKNAARGR-LSFHAKPHWLQTMADTALSI 180 Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180 + + + EC G P+P+ W KNG+ + +G + +D G L I +D+G YQC Sbjct: 181 EAN-LFWEC-KANGKPKPSYSWLKNGEQVAAEGRIQ---IDNGALSIAVLNLSDSGMYQC 235 Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVV--AQTGSSVTFQCRVGGDPLPDVLWRRS 238 +A N G S+ + + P P + A++GS VT +C+ P LW++ Sbjct: 236 VAENKHGIIYSSAQLMVLASPPNFSKSPLKALLKARSGSEVTLECKPEAWPPAISLWKK- 294 Query: 239 AGGGNMP-LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297 G +P R+ +L +G++++ N D G Y+C A+N G S +G L + +P I + Sbjct: 295 -GNEILPRTERINLLPNGTIKIANATRQDAGSYTCIAKNQFGTASTTGKLLITEPTRITM 353 Query: 298 SPNSVNVESGNVARFTCTATGRP--EPTMFWSVEG 330 P + + G A C P + + W+ G Sbjct: 354 RPTNTEIIVGESAVLPCQIAFDPALDVSFSWAFNG 388 Score = 102 bits (245), Expect = 5e-20 Identities = 89/363 (24%), Positives = 156/363 (42%), Gaps = 37/363 (10%) Query: 142 WKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200 W N DSR + + G+L I ++D G Y C+ N + + + + Sbjct: 6 WIFNEYPHFVQQDSRRFISQETGSLYIAKVERSDVGNYTCVVNNTVTGDKVLSSPTPLVL 65 Query: 201 KPYLITG----------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRV 249 + + G PE V A S+V +C G+P+P++ WRR++G +P +V Sbjct: 66 RSDGVMGEYEPKIEVHFPESVPAAKESAVKLECFALGNPVPEISWRRTSG---IPFPSKV 122 Query: 250 KVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNVES 306 K+ + + L + N D G Y C AEN G +A G L+ + P ++ ++++E+ Sbjct: 123 KMKNSNAVLEIPNFQQEDAGTYECVAENRRGKNAARGRLSFHAKPHWLQTMADTALSIEA 182 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 + C A G+P+P+ W G + + D + + VL ++D+ Sbjct: 183 NLF--WECKANGKPKPSYSWLKNGEQVAAEGRIQIDNGALS-----IAVLNLSDSGMYQ- 234 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA--VFPCTAICT 424 C A N G + +L V + PP + P L +S + C Sbjct: 235 -----CVAENKHGIIYSSAQLMVLAS----PPNFSKSPLKALLKARSGSEVTLECKPEAW 285 Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 P I W E L + R N+ +GT+ + + + D+G+YTC+A ++ G +G LL+ Sbjct: 286 PPAISLWKKGNEILPRTERINLLPNGTIKIANATRQDAGSYTCIAKNQFGTASTTGKLLI 345 Query: 485 DSP 487 P Sbjct: 346 TEP 348 Score = 100 bits (239), Expect = 3e-19 Identities = 87/304 (28%), Positives = 128/304 (42%), Gaps = 24/304 (7%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P+ ++ D ++ C+A G P P+ W K G V ++ I G + Sbjct: 167 PHWLQTMADTALSIEANLFWECKANGKPKPSYSWLKNGEQVAAEGRIQI--DNGALSIAV 224 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTVVLEC 129 + SD+G+Y C A N +G S +A L V F P ++ G V LEC Sbjct: 225 LN---LSDSGMYQCVAENKHGIIYS-SAQLMVLASPPNFSKSPLKALLKARSGSEVTLEC 280 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189 P P ++ WKK + L R++L+ G + I +A + DAG Y CIA+N GT Sbjct: 281 KPEAWPPAISL-WKKGNEIL--PRTERINLLPNGTIKIANATRQDAGSYTCIAKNQFGT- 336 Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-------- 241 S L I + P + G S C++ DP DV + + G Sbjct: 337 ASTTGKLLITEPTRITMRPTNTEIIVGESAVLPCQIAFDPALDVSFSWAFNGQLIDFQRD 396 Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301 GN RV G L + N+ L+ G+Y C + V ++S S L V PP P+ Sbjct: 397 GN-HFERVGGSVSGDLMIRNIQLSHGGKYVCLIDTDVESLSTSAILVVKGPPG---PPDK 452 Query: 302 VNVE 305 V VE Sbjct: 453 VTVE 456 >UniRef50_Q98902 Cluster: Neural cell adhesion molecule L1 precursor; n=7; Clupeocephala|Rep: Neural cell adhesion molecule L1 precursor - Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) Length = 1277 Score = 145 bits (352), Expect = 6e-33 Identities = 170/727 (23%), Positives = 289/727 (39%), Gaps = 92/727 (12%) Query: 121 QGDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179 +G T+ LEC+ +G P P V W +K+G+ + + + D L + ++D G YQ Sbjct: 272 RGQTLELECIV-QGLPTPKVSWLRKDGE--MSESRISKDMFDR-RLQFTNISESDGGEYQ 327 Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239 C A N G R T+ + PY P + G +V C+ G P P + W + Sbjct: 328 CTAENVQG-RTFHTYTVTVEASPYWTNAPVSQLYAPGETVKLDCQADGIPSPTITWTVNG 386 Query: 240 G--GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSI- 295 R + + GSL L +VI D Y C+A N G + A+ + V + PP I Sbjct: 387 VPLSATSLEPRRSLTESGSLILKDVIFGDTAIYQCQASNKHGTILANTNVYVIELPPQIL 446 Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355 + N+ G A C G P+P + W ++ D G+ + Sbjct: 447 TENGNTYTFVEGQKALLECETFGSPKPKVTWESSSISLLL-----ADPRVNLLTNGGLEI 501 Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415 ++ D+ + S ++ V + + S PP + P A Sbjct: 502 ANVSHDDEGIYTCLVQGSNISVNAEVEVLNRTVILS----PPQALRLQPGKT-------A 550 Query: 416 VFPCTAICTPE---PIIAWYFEGEALIQNHR-RNVTNDGT-LVLKDLDKSDSGTYTCVAS 470 +F C + P+ P++ W + + ++H + T DG L++ +++ D G YTC Sbjct: 551 IFTCLYVTDPKLSSPLLQWRKNDQKIFESHSDKKYTFDGPGLIISNVEPGDEGVYTCQII 610 Query: 471 SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530 ++ S L + P PP N VTL+W+ + Sbjct: 611 TKLDMVEASSTLTL----------------CDRPDPPVHLQVTNAKHRVVTLNWTPGDD- 653 Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590 +S IL Y VE F + + N GW + R +V L P ++Y F V Sbjct: 654 NNSPILEYVVE-FEDQDMKEN-------GWEELKRVAADKKHVNLPLWPYMSYRFRVIAI 705 Query: 591 NSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIK 650 N G S PS +SD D+ SN + R+ E+T D T+ Sbjct: 706 NDQGKSDPSKLSDLYKTPADAPD-------SNPEDVRS-----------EST--DPDTLV 745 Query: 651 LMWEILNFYYLEG-----LFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEF 705 + WE ++ G L ++ R + + +E TI F +T ++ ++ +E Sbjct: 746 ITWEEMDKRNFNGPDFKYLVMWRRVVGSGPDWHEEYTI-----APPFIVTDVQNFSAFEI 800 Query: 706 FLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIIT 765 + KK G + + + +DVP P+N+ + + N+TT+ + WS + + G + Sbjct: 801 KVQAVNKKGLGPEPDPIIGYSGEDVPLEAPLNLGVLLENSTTIRVTWSAVDKETVRGHLL 860 Query: 766 GYNVVVNW-----LDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGP 820 GY + + W +++V + T ++ I TNL Y + I+A G GP Sbjct: 861 GYKIYLTWGHHRNSRAQEPENIVMVQTGANEEKKSI-TNLRPYCHYDLAISAFNSKGEGP 919 Query: 821 FSQKVYF 827 S+K F Sbjct: 920 LSEKTSF 926 Score = 144 bits (348), Expect = 2e-32 Identities = 127/477 (26%), Positives = 193/477 (40%), Gaps = 32/477 (6%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGG---L 66 P I QP VTV + + C A G+PSP W K G SD + G Sbjct: 51 PAITTQPESVTVFSVEDLVMRCEASGNPSPTFHWTKDGEEFDPSSDPEMKVTEEAGSSVF 110 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126 + L T + G Y C A+N GTA S A L + + + + ++++ G ++ Sbjct: 111 YTLSNTMDTLKQYQGKYICYASNELGTAVSNAAVLMIDAPPVQQKEKKVTEKAEAGHSIA 170 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG----NLVIQDARQTDAGRYQCIA 182 L C PP+ S +P ++W N + D M DG NL+ +D+R Q +A Sbjct: 171 LSCNPPQSSMQPIIHWMDNRLRHIRLSDRVMVGKDGNLYFANLLTEDSRNDYTCNIQYLA 230 Query: 183 RNAAGTRESAIATLKI------HIKPYLI--TGPEDVV-AQTGSSVTFQCRVGGDPLPDV 233 +E T+ + +P ++ TG A G ++ +C V G P P V Sbjct: 231 TRTILAKEPITLTVNPSNLVPRNRRPQMMRPTGSHSTYHALRGQTLELECIVQGLPTPKV 290 Query: 234 LWRRSAGGGNMPLGRV-KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292 W R G M R+ K + D L+ N+ +D GEY C AEN G + +TV Sbjct: 291 SWLRK--DGEMSESRISKDMFDRRLQFTNISESDGGEYQCTAENVQGRTFHTYTVTVEAS 348 Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352 P +P S G + C A G P PT+ W+V G P +S Sbjct: 349 PYWTNAPVSQLYAPGETVKLDCQADGIPSPTITWTVNG-----VP-LSATSLEPRRSLTE 402 Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412 L + D D+ C A N G+ + V + PP I+T + T Sbjct: 403 SGSLILKDVIFGDTA-IYQCQASNKHGTILANTNVYVI---ELPPQILTENGNTYTFVEG 458 Query: 413 SMAVFPCTAICTPEPIIAWYFEG-EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468 A+ C +P+P + W L+ + R N+ +G L + ++ D G YTC+ Sbjct: 459 QKALLECETFGSPKPKVTWESSSISLLLADPRVNLLTNGGLEIANVSHDDEGIYTCL 515 Score = 113 bits (272), Expect = 3e-23 Identities = 86/296 (29%), Positives = 137/296 (46%), Gaps = 18/296 (6%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS---DTHRSILP 62 VT +PY P+ A + L+C+A G PSP I W GV + + + RS+ Sbjct: 343 VTVEASPYWTNAPVSQLYAPGETVKLDCQADGIPSPTITWTVNGVPLSATSLEPRRSLTE 402 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS-AQ 121 +G L G D +Y C+A+N +GT + N ++V L + E + + + Sbjct: 403 SGSLILKDVIFG----DTAIYQCQASNKHGTILA-NTNVYVIELPPQILTENGNTYTFVE 457 Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181 G +LEC GSP+P V W+ + +LL D R++L+ G L I + D G Y C+ Sbjct: 458 GQKALLEC-ETFGSPKPKVTWESSSISLLL-ADPRVNLLTNGGLEIANVSHDDEGIYTCL 515 Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP---LPDVLWRRS 238 + G+ S A +++ + +++ P+ + Q G + F C DP P + WR++ Sbjct: 516 VQ---GSNISVNAEVEVLNRTVILSPPQALRLQPGKTAIFTCLYVTDPKLSSPLLQWRKN 572 Query: 239 AGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293 K DG L + NV DEG Y+C+ + V AS LT+ D P Sbjct: 573 DQKIFESHSDKKYTFDGPGLIISNVEPGDEGVYTCQIITKLDMVEASSTLTLCDRP 628 Score = 88.2 bits (209), Expect = 1e-15 Identities = 99/392 (25%), Positives = 156/392 (39%), Gaps = 49/392 (12%) Query: 113 EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVI---- 167 +PES + +V+ C G+P P +W K+G+ D M + + G+ V Sbjct: 56 QPESVTVFSVEDLVMRC-EASGNPSPTFHWTKDGEEFDPSSDPEMKVTEEAGSSVFYTLS 114 Query: 168 --QDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVV---AQTGSSVTFQ 222 D + G+Y C A N GT S A L I P + E V A+ G S+ Sbjct: 115 NTMDTLKQYQGKYICYASNELGTAVSNAAVLMIDAPP--VQQKEKKVTEKAEAGHSIALS 172 Query: 223 CRVGGDPL-PDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE-GEYSCEAEN-SVG 279 C + P + W + RV V DG+L N++ D +Y+C + + Sbjct: 173 CNPPQSSMQPIIHWMDNRLRHIRLSDRVMVGKDGNLYFANLLTEDSRNDYTCNIQYLATR 232 Query: 280 AVSASGYLTVYDPPSINLSP--------------NSVNVESGNVARFTCTATGRPEPTMF 325 + A +T+ PS NL P ++ + G C G P P + Sbjct: 233 TILAKEPITLTVNPS-NLVPRNRRPQMMRPTGSHSTYHALRGQTLELECIVQGLPTPKVS 291 Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385 W + + + +S+D + F I+++D + + C+A N G +F Sbjct: 292 W-LRKDGEMSESRISKDMFDRRLQFTN-----ISESDGGEYQ----CTAENVQGRTFHTY 341 Query: 386 KLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH--- 442 +TV + P TN P +Q C A P P I W G L Sbjct: 342 TVTVEAS-----PYWTNAPVSQLYAPGETVKLDCQADGIPSPTITWTVNGVPLSATSLEP 396 Query: 443 RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 RR++T G+L+LKD+ D+ Y C AS++HG Sbjct: 397 RRSLTESGSLILKDVIFGDTAIYQCQASNKHG 428 Score = 66.9 bits (156), Expect = 3e-09 Identities = 50/180 (27%), Positives = 75/180 (41%), Gaps = 13/180 (7%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPA 63 YV + E T Q A L C GSP P + W + L+++D ++L Sbjct: 437 YVIELPPQILTENGNTYTFVEGQKALLECETFGSPKPKVTWESSSISLLLADPRVNLLTN 496 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123 GGL + H D G+Y C G+ S NA + V + R P++ + G Sbjct: 497 GGLEIANVS----HDDEGIYTCLV---QGSNISVNAEVEV-LNRTVILSPPQALRLQPGK 548 Query: 124 TVVLECL---PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180 T + CL P+ S P + W+KN Q + + + DG L+I + D G Y C Sbjct: 549 TAIFTCLYVTDPKLS-SPLLQWRKNDQKIFESHSDKKYTFDGPGLIISNVEPGDEGVYTC 607 Score = 55.2 bits (127), Expect = 1e-05 Identities = 37/126 (29%), Positives = 58/126 (46%), Gaps = 4/126 (3%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753 IT+LR Y Y+ + F K EG S T + VP GPP++++M + + + L W+ Sbjct: 896 ITNLRPYCHYDLAISAFNSKGEGPLSEKTSFMTPEGVP-GPPMSMQMTSPSESEITLHWT 954 Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAE 813 PP NGI+ GY++ + N V ++ + T L + L Y + A Sbjct: 955 PP--SKPNGILLGYSLQYRKMQSDDNPLQV-VDIASPEITHLTLKGLDRHSHYQFLLMAR 1011 Query: 814 TIIGLG 819 T G G Sbjct: 1012 TAAGKG 1017 Score = 50.8 bits (116), Expect = 2e-04 Identities = 78/354 (22%), Positives = 136/354 (38%), Gaps = 39/354 (11%) Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG--RVKVLDD- 254 + I P + T PE V + + +C G+P P W + G P +KV ++ Sbjct: 47 LKIPPAITTQPESVTVFSVEDLVMRCEASGNPSPTFHWTKD-GEEFDPSSDPEMKVTEEA 105 Query: 255 GS---LRLDN---VILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV--NVES 306 GS L N + +G+Y C A N +G ++ + + D P + V E+ Sbjct: 106 GSSVFYTLSNTMDTLKQYQGKYICYASNELGTAVSNAAVLMIDAPPVQQKEKKVTEKAEA 165 Query: 307 GNVARFTCT-ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365 G+ +C +P + W R I F +LT D Sbjct: 166 GHSIALSCNPPQSSMQPIIHWMDNRLRHIRLSDRVMVGKDGNLYF--ANLLT------ED 217 Query: 366 SRNTIVCSAVNYAGSSFVRGK----LTVTSDD----DRPPPIITNGPSNQTL-PIKSMAV 416 SRN C+ + Y + + K LTV + +R P ++ S+ T ++ + Sbjct: 218 SRNDYTCN-IQYLATRTILAKEPITLTVNPSNLVPRNRRPQMMRPTGSHSTYHALRGQTL 276 Query: 417 -FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 C P P ++W + + ++ D L ++ +SD G Y C A + G+ Sbjct: 277 ELECIVQGLPTPKVSWLRKDGEMSESRISKDMFDRRLQFTNISESDGGEYQCTAENVQGR 336 Query: 476 YVWSGALLVDSPINPNIHFFRAADVSSL--PGPPTKPITHNVTDTSVTLSWSQN 527 + + V++ +P ++ A VS L PG K S T++W+ N Sbjct: 337 TFHTYTVTVEA--SP---YWTNAPVSQLYAPGETVKLDCQADGIPSPTITWTVN 385 Score = 35.9 bits (79), Expect = 6.7 Identities = 32/105 (30%), Positives = 44/105 (41%), Gaps = 10/105 (9%) Query: 393 DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL--IQNHRRNVTND- 449 D + PP IT P + T+ V C A P P W +GE + VT + Sbjct: 46 DLKIPPAITTQPESVTVFSVEDLVMRCEASGNPSPTFHWTKDGEEFDPSSDPEMKVTEEA 105 Query: 450 GTLVLKDLD------KSDSGTYTCVASSRHGKYVWSGA-LLVDSP 487 G+ V L K G Y C AS+ G V + A L++D+P Sbjct: 106 GSSVFYTLSNTMDTLKQYQGKYICYASNELGTAVSNAAVLMIDAP 150 >UniRef50_UPI0000E4A6A5 Cluster: PREDICTED: similar to heparan sulfate proteoglycan perlecan; n=4; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to heparan sulfate proteoglycan perlecan - Strongylocentrotus purpuratus Length = 2331 Score = 145 bits (351), Expect = 7e-33 Identities = 126/476 (26%), Positives = 208/476 (43%), Gaps = 47/476 (9%) Query: 15 IEQPL---DVTVARHQPATLNCRAGGSPSP-AIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 +EQ L ++ V + A +C + G+P+ I W + + S ++ + GL + Sbjct: 1263 VEQELLLRELEVIEGETAVFSCTSPGTPAGYTITWRRVSQRMPS----TVSISNGLLTIP 1318 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130 + AG Y+C N +G + TL+V VL + P ++ G+ + + C Sbjct: 1319 QARSQY---AGQYYCIVGNEHGYQQDL-VTLYVLVL-PSLSISPTTQTVTAGEIIRISCF 1373 Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190 G+ W K G +L + GG L I A TDAG+Y+C+ N AG R+ Sbjct: 1374 A-EGTQPITCEWSKYGGSL-----PPTAIQSGGILQISPATATDAGQYRCVCSNTAGFRD 1427 Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250 S + T+++ + P + P G SV F C+ G P P + W + G L Sbjct: 1428 SYM-TVRVQVIPTVTAIPARETRAIGGSVEFSCQATGTPPPQITWEKEDG----VLPAQH 1482 Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV--NVESGN 308 + +G L L ++ DEG Y C A N G+ A L ++ P++ ++ N+ + G Sbjct: 1483 RITNGVLSLISLRDGDEGRYVCTATNQAGSSKAYARLFLHAAPTVQITVNTTVHYIRVGE 1542 Query: 309 VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368 F C +TG P P + W+ + I + V G LTI +D Sbjct: 1543 TTTFECLSTGDPTPVVTWTKVNSEMPI-----------SVVLQGAR-LTIPQVSLSDV-G 1589 Query: 369 TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428 C+A N GS + L V + P +T PS +T P+ S F C A P P Sbjct: 1590 FYRCTATNIVGSRTSQVFLYVQA-----APQLTVVPSTRTAPVGSTLEFSCLAGGFPTPE 1644 Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 I W+ + L N++ ++G L + ++ ++D GTY C+A+++ G L+V Sbjct: 1645 ITWHKDDGDLPDNYQ---IDNGLLTITNVKEADEGTYVCIATNQGGSTEHRARLVV 1697 Score = 131 bits (317), Expect = 1e-28 Identities = 120/467 (25%), Positives = 201/467 (43%), Gaps = 40/467 (8%) Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL---EPESKQSAQGDTVVLECLPPRG 134 +DAG++ A+N +G S A + + V+ + R+ +P++ + +G+TV C Sbjct: 698 NDAGIFIFTASNRFG---SGTAEVRLEVVGQAMRVVINDPQTVEVPEGETVQFVCRGISQ 754 Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194 +P + W ++ TL + M G L I R +DAG+Y C+ N T + A A Sbjct: 755 TPAYTIAWSRSDGTLPTNARDFM-----GILTIDTVRLSDAGQYVCMGSNQRDTAD-AYA 808 Query: 195 TLKIHI---KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251 TL + +P + P + G V F+C G+P P + W GG L Sbjct: 809 TLIVTSSVQEPTVRIEPRFIRITEGDRVEFRCIATGNPTPTLRWSGGQGG---VLNSEST 865 Query: 252 LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP--PSINLSPNSVNVESGNV 309 ++G + +DE EY CEA NS G + L V PS+ +SP S +V G Sbjct: 866 FENGLFVIPKARASDEAEYFCEATNSAGMATIRTVLYVSPSRVPSVTISPASESVSEGER 925 Query: 310 ARFTCTATGRPEPTMFWS-VEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368 F C ATG P P WS ++G+ P +R++ + V VT + Sbjct: 926 VIFYCQATGDPAPERTWSRIDGD----MPSSAREE-NGYLVISAVTY---------EVEG 971 Query: 369 TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428 C+A N GS + ++T+++D R P + P+ T+ + V C P P Sbjct: 972 VYRCTATNSHGSDYSDAQITISTDSRRSPTARID-PAEITVTQGATQVLRCLTTGVPTPT 1030 Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPI 488 I W L N + +G L + + D +D Y+C A++ G + + ++ Sbjct: 1031 ITWTRGSGPLSANQQ---ALNGVLRIINADVTDRDMYSCTATNIAGSSTATAYVEIERRE 1087 Query: 489 NPNIHFFRAADVSSLPGPPTKPITHNVTD-TSVTLSWSQNNKIGSSS 534 +P I + ++ G + ++ + T+SWS+ N SS Sbjct: 1088 SPVIEILPYSTYIAIDGDNIQIQCRILSGIPTPTVSWSRANGAPLSS 1134 Score = 128 bits (308), Expect = 1e-27 Identities = 129/494 (26%), Positives = 209/494 (42%), Gaps = 55/494 (11%) Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWY--KGGVLVVSDTHRSILPAG 64 +S + P + +P + + C A G+P+P +RW +GGVL T + Sbjct: 814 SSVQEPTVRIEPRFIRITEGDRVEFRCIATGNPTPTLRWSGGQGGVLNSESTFEN----- 868 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR-EEFRLEPESKQSAQGD 123 GLF + SD Y+CEATNS G A R L+V+ R + P S+ ++G+ Sbjct: 869 GLFVIPKARA---SDEAEYFCEATNSAGMATIR-TVLYVSPSRVPSVTISPASESVSEGE 924 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCIA 182 V+ C G P P W + DGD + G LVI G Y+C A Sbjct: 925 RVIFYC-QATGDPAPERTWSR------IDGDMPSSAREENGYLVISAVTYEVEGVYRCTA 977 Query: 183 RNAAGTRES-AIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239 N+ G+ S A T+ + P P ++ G++ +C G P P + W R + Sbjct: 978 TNSHGSDYSDAQITISTDSRRSPTARIDPAEITVTQGATQVLRCLTTGVPTPTITWTRGS 1037 Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV--YDPPSINL 297 G PL + +G LR+ N + D YSC A N G+ +A+ Y+ + + P I + Sbjct: 1038 G----PLSANQQALNGVLRIINADVTDRDMYSCTATNIAGSSTATAYVEIERRESPVIEI 1093 Query: 298 SPNS--VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355 P S + ++ N+ +G P PT+ WS + ++ D + V Sbjct: 1094 LPYSTYIAIDGDNIQIQCRILSGIPTPTVSWSRANGAPL-----------SSNTNDEMGV 1142 Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT-LPIKSM 414 LTI +++ +C+ N AGS+ + V + P I+ P+N + Sbjct: 1143 LTIMGVTA-ENQGAYICTGTNSAGSATATATIRV-----QGLPQISITPTNPAEFRVGET 1196 Query: 415 AVFPCTAICTPEPIIAW-YFEGEALIQNHRR--NVTNDGTLV--LKDLDKSDSGTYTCVA 469 AV C A P P + W E + Q N+ + + + ++ + +D+G+Y C A Sbjct: 1197 AVLECVATGEPLPTVQWMVMNNERVYQPIAAAFNMEEESSAMHYIQSVSMNDAGSYMCRA 1256 Query: 470 SSRHGKYVWSGALL 483 + G YV LL Sbjct: 1257 ENGAG-YVEQELLL 1269 Score = 127 bits (306), Expect = 2e-27 Identities = 128/479 (26%), Positives = 193/479 (40%), Gaps = 52/479 (10%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64 YV+ P + P +V+ + C+A G P+P W + + D S Sbjct: 902 YVSPSRVPSVTISPASESVSEGERVIFYCQATGDPAPERTWSR----IDGDMPSSAREEN 957 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARS-RNATLHVAVLREEF-RLEPESKQSAQG 122 G + A V GVY C ATNS+G+ S T+ R R++P QG Sbjct: 958 GYLVISAVTYEVE---GVYRCTATNSHGSDYSDAQITISTDSRRSPTARIDPAEITVTQG 1014 Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182 T VL CL G P P + W + L S G L I +A TD Y C A Sbjct: 1015 ATQVLRCLTT-GVPTPTITWTRGSGPL-----SANQQALNGVLRIINADVTDRDMYSCTA 1068 Query: 183 RNAAGTRES-AIATLKIHIKPYLITGPEDV-VAQTGSSVTFQCRV-GGDPLPDVLWRRSA 239 N AG+ + A ++ P + P +A G ++ QCR+ G P P V W R+ Sbjct: 1069 TNIAGSSTATAYVEIERRESPVIEILPYSTYIAIDGDNIQIQCRILSGIPTPTVSWSRAN 1128 Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299 G PL + G L + V ++G Y C NS G+ +A+ + V P I+++P Sbjct: 1129 GA---PLSSNTNDEMGVLTIMGVTAENQGAYICTGTNSAGSATATATIRVQGLPQISITP 1185 Query: 300 -NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP-GMSRDKYHATAVFDGVTVLT 357 N G A C ATG P PT+ W V N + P + + ++ + ++ Sbjct: 1186 TNPAEFRVGETAVLECVATGEPLPTVQWMVMNNERVYQPIAAAFNMEEESSAMHYIQSVS 1245 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417 +ND + +C A N G+ +V +L + R +I AVF Sbjct: 1246 MNDA------GSYMCRAEN--GAGYVEQELLL-----RELEVIEG----------ETAVF 1282 Query: 418 PCTAICTPEP-IIAWYFEGEALIQNHRRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHG 474 CT+ TP I W + Q V+ ++G L + +G Y C+ + HG Sbjct: 1283 SCTSPGTPAGYTITW----RRVSQRMPSTVSISNGLLTIPQARSQYAGQYYCIVGNEHG 1337 Score = 122 bits (294), Expect = 6e-26 Identities = 110/380 (28%), Positives = 163/380 (42%), Gaps = 35/380 (9%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P + P TV + ++C A G+ W K G + + +GG+ + Sbjct: 1351 PSLSISPTTQTVTAGEIIRISCFAEGTQPITCEWSKYG----GSLPPTAIQSGGILQISP 1406 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131 +DAG Y C +N+ G R T+ V V+ + P + A G +V C Sbjct: 1407 ATA---TDAGQYRCVCSNTAGF-RDSYMTVRVQVIPTVTAI-PARETRAIGGSVEFSC-Q 1460 Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191 G+P P + W+K L H + G L + R D GRY C A N AG+ + Sbjct: 1461 ATGTPPPQITWEKEDGVL-----PAQHRITNGVLSLISLRDGDEGRYVCTATNQAGSSK- 1514 Query: 192 AIATLKIHIKPYL-ITGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249 A A L +H P + IT V + G + TF+C GDP P V W + MP+ Sbjct: 1515 AYARLFLHAAPTVQITVNTTVHYIRVGETTTFECLSTGDPTPVVTWTKV--NSEMPIS-- 1570 Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309 VL L + V L+D G Y C A N VG+ ++ +L V P + + P++ G+ Sbjct: 1571 VVLQGARLTIPQVSLSDVGFYRCTATNIVGSRTSQVFLYVQAAPQLTVVPSTRTAPVGST 1630 Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369 F+C A G P P + W + G D Y + +G +LTI + + D T Sbjct: 1631 LEFSCLAGGFPTPEITWHKD-------DGDLPDNYQ---IDNG--LLTITNVKEAD-EGT 1677 Query: 370 IVCSAVNYAGSSFVRGKLTV 389 VC A N GS+ R +L V Sbjct: 1678 YVCIATNQGGSTEHRARLVV 1697 Score = 116 bits (279), Expect = 4e-24 Identities = 136/510 (26%), Positives = 207/510 (40%), Gaps = 65/510 (12%) Query: 31 LNCRA-GGSPSPAIRWYKG-GVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88 + CR G P+P + W + G + S+T+ + G L + T + G Y C T Sbjct: 1109 IQCRILSGIPTPTVSWSRANGAPLSSNTNDEM---GVLTIMGVTA----ENQGAYICTGT 1161 Query: 89 NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWK-KNGQ 147 NS G+A + AT+ V L + + G+T VLEC+ G P P V W N + Sbjct: 1162 NSAGSATA-TATIRVQGLPQISITPTNPAEFRVGETAVLECVAT-GEPLPTVQWMVMNNE 1219 Query: 148 TLLFDGDSRMHLVDGGNLV--IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205 + + ++ + + + IQ DAG Y C A N AG +++ L+ Sbjct: 1220 RVYQPIAAAFNMEEESSAMHYIQSVSMNDAGSYMCRAENGAG-----------YVEQELL 1268 Query: 206 TGPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264 +V+ G + F C G P + WRR + MP + +G L + Sbjct: 1269 LRELEVIE--GETAVFSCTSPGTPAGYTITWRRVSQ--RMP--STVSISNGLLTIPQARS 1322 Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTM 324 G+Y C N G L V PS+++SP + V +G + R +C A G T Sbjct: 1323 QYAGQYYCIVGNEHGYQQDLVTLYVLVLPSLSISPTTQTVTAGEIIRISCFAEGTQPITC 1382 Query: 325 FWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS-RNTIVCSAVNYAGSSFV 383 WS G TA+ G +L I+ D+ + VCS N AG F Sbjct: 1383 EWSKYGG-----------SLPPTAIQSG-GILQISPATATDAGQYRCVCS--NTAG--FR 1426 Query: 384 RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR 443 +TV + P +T P+ +T I F C A TP P I W E L HR Sbjct: 1427 DSYMTVRV---QVIPTVTAIPARETRAIGGSVEFSCQATGTPPPQITWEKEDGVLPAQHR 1483 Query: 444 RNVTNDGTLVLKDLDKSDSGTYTCVASSRHG------KYVWSGALLVDSPINPNIHFFRA 497 +TN G L L L D G Y C A+++ G + A V +N +H+ R Sbjct: 1484 --ITN-GVLSLISLRDGDEGRYVCTATNQAGSSKAYARLFLHAAPTVQITVNTTVHYIRV 1540 Query: 498 ADVSSL----PGPPTKPITHNVTDTSVTLS 523 + ++ G PT +T ++ + +S Sbjct: 1541 GETTTFECLSTGDPTPVVTWTKVNSEMPIS 1570 Score = 108 bits (260), Expect = 8e-22 Identities = 113/453 (24%), Positives = 172/453 (37%), Gaps = 58/453 (12%) Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH-------SD 79 + A L C A G P P ++W +V + R P F + +H +D Sbjct: 1195 ETAVLECVATGEPLPTVQW------MVMNNERVYQPIAAAFNMEEESSAMHYIQSVSMND 1248 Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139 AG Y C A N G +LRE + +G+T V C P Sbjct: 1249 AGSYMCRAENGAGYVEQE------LLLRE--------LEVIEGETAVFSCTSPGTPAGYT 1294 Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199 + W++ Q + S + + G L I AR AG+Y CI N G ++ + TL + Sbjct: 1295 ITWRRVSQRM----PSTVS-ISNGLLTIPQARSQYAGQYYCIVGNEHGYQQDLV-TLYVL 1348 Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL 259 + P L P G + C G W S GG++P ++ G L++ Sbjct: 1349 VLPSLSISPTTQTVTAGEIIRISCFAEGTQPITCEW--SKYGGSLPPTAIQ--SGGILQI 1404 Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGR 319 D G+Y C N+ G + + V P++ P G F+C ATG Sbjct: 1405 SPATATDAGQYRCVCSNTAGFRDSYMTVRVQVIPTVTAIPARETRAIGGSVEFSCQATGT 1464 Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379 P P + W E + P R + +GV L I+ D ++ R VC+A N AG Sbjct: 1465 PPPQITWEKEDG---VLPAQHR-------ITNGVLSL-ISLRDGDEGR--YVCTATNQAG 1511 Query: 380 SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-YFEGEAL 438 SS +L + + P IT + + + F C + P P++ W E Sbjct: 1512 SSKAYARLFLHA---APTVQITVNTTVHYIRVGETTTFECLSTGDPTPVVTWTKVNSEMP 1568 Query: 439 IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471 I V L + + SD G Y C A++ Sbjct: 1569 IS----VVLQGARLTIPQVSLSDVGFYRCTATN 1597 Score = 93.1 bits (221), Expect = 4e-17 Identities = 83/317 (26%), Positives = 130/317 (41%), Gaps = 31/317 (9%) Query: 165 LVIQDARQTDAGRYQCIARN--AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQ 222 L I++ R DAG + A N +GT E + + ++ +I P+ V G +V F Sbjct: 690 LQIRNLRANDAGIFIFTASNRFGSGTAEVRLEVVGQAMR-VVINDPQTVEVPEGETVQFV 748 Query: 223 CR-VGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281 CR + P + W RS G +P + G L +D V L+D G+Y C N Sbjct: 749 CRGISQTPAYTIAWSRS--DGTLPTNARDFM--GILTIDTVRLSDAGQYVCMGSNQRDTA 804 Query: 282 SASGYLTV---YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPG 338 A L V P++ + P + + G+ F C ATG P PT+ WS G Sbjct: 805 DAYATLIVTSSVQEPTVRIEPRFIRITEGDRVEFRCIATGNPTPTLRWS----------G 854 Query: 339 MSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398 ++ + F+ + I +D C A N AG + +R L V+ P Sbjct: 855 GQGGVLNSESTFEN-GLFVIPKARASDEAE-YFCEATNSAGMATIRTVLYVSPS---RVP 909 Query: 399 IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-YFEGEALIQNHRRNVTNDGTLVLKDL 457 +T P+++++ +F C A P P W +G+ N G LV+ + Sbjct: 910 SVTISPASESVSEGERVIFYCQATGDPAPERTWSRIDGDMPSSAREEN----GYLVISAV 965 Query: 458 DKSDSGTYTCVASSRHG 474 G Y C A++ HG Sbjct: 966 TYEVEGVYRCTATNSHG 982 Score = 73.3 bits (172), Expect = 4e-11 Identities = 55/188 (29%), Positives = 85/188 (45%), Gaps = 19/188 (10%) Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH-SDAGVYWC 85 + T C + G P+P + W K V S+ S++ G R T +V SD G Y C Sbjct: 1542 ETTTFECLSTGDPTPVVTWTK----VNSEMPISVVLQGA----RLTIPQVSLSDVGFYRC 1593 Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145 ATN G+ R+ L+V + + P ++ + G T+ CL G P P + W K+ Sbjct: 1594 TATNIVGS-RTSQVFLYVQAA-PQLTVVPSTRTAPVGSTLEFSCLAG-GFPTPEITWHKD 1650 Query: 146 GQTLLFDGD-SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL 204 DGD + +D G L I + ++ D G Y CIA N G+ E + + PY Sbjct: 1651 ------DGDLPDNYQIDNGLLTITNVKEADEGTYVCIATNQGGSTEHRARLVVGELIPYF 1704 Query: 205 ITGPEDVV 212 + P+ + Sbjct: 1705 VQMPQSYI 1712 Score = 35.9 bits (79), Expect = 6.7 Identities = 34/106 (32%), Positives = 44/106 (41%), Gaps = 8/106 (7%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 AP + P T +C AGG P+P I W+K D + GL L Sbjct: 1613 APQLTVVPSTRTAPVGSTLEFSCLAGGFPTPEITWHKDD----GDLPDNYQIDNGL--LT 1666 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPES 116 T+ + +D G Y C ATN G+ R A L V L F P+S Sbjct: 1667 ITNVK-EADEGTYVCIATNQGGSTEHR-ARLVVGELIPYFVQMPQS 1710 >UniRef50_Q4T8B2 Cluster: Chromosome undetermined SCAF7849, whole genome shotgun sequence; n=3; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF7849, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1319 Score = 145 bits (351), Expect = 7e-33 Identities = 124/460 (26%), Positives = 197/460 (42%), Gaps = 46/460 (10%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 + P + E P +T + +L C A G+P P W K G + SD L A L Sbjct: 51 QPPVLSEVPKSLTAFSLEDISLPCEATGNPPPTFEWVKDGQRIRSDLASGTLQAKEDDLL 110 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 + G Y C A+N YGTA ++ + V + + + K++ +G++++L C Sbjct: 111 QQFEGH-------YRCYASNIYGTAMTQIVHVIVEAQPVLLKQQKDHKRAYEGESLILSC 163 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIARNAAGT 188 PP S P ++W + D M +DG NL + ++D+ + Y C A+ A Sbjct: 164 NPPESSTPPFIHWMDKQMIHISQSDRVMVGLDG-NLYFSNLLKSDSRKDYMCNAQYLA-- 220 Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248 + TL T S+++ + +P P+V W++ G GR Sbjct: 221 ---VMTTL------------------TESAISLTV-LPSEPTPEVEWKKKDGSLEETSGR 258 Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGN 308 + +++ L D+GEY C+A NS G + S +TV P P S G Sbjct: 259 GDKYNRW-FHFESIGLKDDGEYECKARNSHGFTTHSFTVTVEAAPYWVKEPTSQLYSPGE 317 Query: 309 VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368 R C A G P PT+ WS+ G P D+ +V GV +L D +D+ Sbjct: 318 TVRLDCQAEGIPTPTITWSINGQ-----PITEVDEEPRRSVSGGVLIL--RDVVFSDTA- 369 Query: 369 TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428 C A N GS+ + L V + PP I+T+ + + C A +P P Sbjct: 370 VYQCEATNKHGSALLNTFLHVV---ELPPQILTSDGLLYKVTEGKNVLMDCEAFGSPRPH 426 Query: 429 IAWYFEGE-ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467 I W E L+ N R ++ +GTLV+ ++D D+G Y+C Sbjct: 427 ITWEAEDRLPLLSNPRVSLMTNGTLVMSEVDHDDAGVYSC 466 Score = 126 bits (304), Expect = 4e-27 Identities = 90/297 (30%), Positives = 147/297 (49%), Gaps = 19/297 (6%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG---VLVVSDTHRSILP 62 VT APY +++P + + L+C+A G P+P I W G V + RS+ Sbjct: 296 VTVEAAPYWVKEPTSQLYSPGETVRLDCQAEGIPTPTITWSINGQPITEVDEEPRRSV-- 353 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121 +GG+ LR V SD VY CEATN +G+A N LHV L + + + + Sbjct: 354 SGGVLILRDV---VFSDTAVYQCEATNKHGSA-LLNTFLHVVELPPQILTSDGLLYKVTE 409 Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181 G V+++C GSP P++ W+ + L + R+ L+ G LV+ + DAG Y C Sbjct: 410 GKNVLMDC-EAFGSPRPHITWEAEDRLPLL-SNPRVSLMTNGTLVMSEVDHDDAGVYSCS 467 Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP-LP--DVLWRRS 238 ++ S A L+++ + ++ PED++ G+SV C+ DP LP V+W++ Sbjct: 468 VKH--NNNISINAHLEVYNRTVILKPPEDLLILRGTSVLLPCKFSTDPRLPKAQVVWKKD 525 Query: 239 AGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293 + + LD +L + +V +D YSCE +++ V+A+G +TV D P Sbjct: 526 GIKLMESKAANKYSFLDTDTLIVSDVQFSDSAPYSCEVISALDHVTATGSITVVDRP 582 Score = 105 bits (251), Expect = 1e-20 Identities = 127/493 (25%), Positives = 196/493 (39%), Gaps = 59/493 (11%) Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 + L LP P P V WKK +L + R + + D G Y+C ARN Sbjct: 230 ISLTVLP--SEPTPEVEWKKKDGSLE-ETSGRGDKYNRW-FHFESIGLKDDGEYECKARN 285 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 + G + T+ + PY + P + G +V C+ G P P + W S G Sbjct: 286 SHGFTTHSF-TVTVEAAPYWVKEPTSQLYSPGETVRLDCQAEGIPTPTITW--SING--Q 340 Query: 245 PLGRV-----KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLS 298 P+ V + + G L L +V+ +D Y CEA N G+ + +L V + PP I S Sbjct: 341 PITEVDEEPRRSVSGGVLILRDVVFSDTAVYQCEATNKHGSALLNTFLHVVELPPQILTS 400 Query: 299 PNSV-NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 + V G C A G P P + W E P +S + + + +G V++ Sbjct: 401 DGLLYKVTEGKNVLMDCEAFGSPRPHITWEAEDR----LPLLSNPR--VSLMTNGTLVMS 454 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417 D +D CS V + + + L V + +I P + + + + Sbjct: 455 EVD---HDDAGVYSCS-VKHNNNISINAHLEVYNRT-----VILKPPEDLLILRGTSVLL 505 Query: 418 PC---TAICTPEPIIAWYFEGEALIQNHRRN---VTNDGTLVLKDLDKSDSGTYTCVASS 471 PC T P+ + W +G L+++ N + TL++ D+ SDS Y+C S Sbjct: 506 PCKFSTDPRLPKAQVVWKKDGIKLMESKAANKYSFLDTDTLIVSDVQFSDSAPYSCEVIS 565 Query: 472 RHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIG 531 +G++ V P PP VTD S+TL+W+ Sbjct: 566 ALDHVTATGSI----------------TVVDRPDPPKHLFLSEVTDDSLTLNWTPGPS-H 608 Query: 532 SSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTEN 591 +S I + VE SRE +T + W + + ++ SL P TY F V T N Sbjct: 609 NSPITEFIVE--SREE---QHTEQEKWKWEETQKVPPNSQHLKLSLRPYCTYRFRVITVN 663 Query: 592 SHGLSGPSPVSDS 604 G S PS SDS Sbjct: 664 EVGRSDPSEPSDS 676 Score = 104 bits (250), Expect = 1e-20 Identities = 85/338 (25%), Positives = 142/338 (42%), Gaps = 17/338 (5%) Query: 79 DAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137 D G Y C+A NS+G T S T+ A + EP S+ + G+TV L+C G P Sbjct: 275 DDGEYECKARNSHGFTTHSFTVTVEAAPYWVK---EPTSQLYSPGETVRLDC-QAEGIPT 330 Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197 P + W NGQ + + V GG L+++D +D YQC A N G+ Sbjct: 331 PTITWSINGQPITEVDEEPRRSVSGGVLILRDVVFSDTAVYQCEATNKHGSALLNTFLHV 390 Query: 198 IHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS 256 + + P ++T + T G +V C G P P + W + RV ++ +G+ Sbjct: 391 VELPPQILTSDGLLYKVTEGKNVLMDCEAFGSPRPHITWEAEDRLPLLSNPRVSLMTNGT 450 Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC-- 314 L + V D G YSC +++ +S + +L VY+ I P + + G C Sbjct: 451 LVMSEVDHDDAGVYSCSVKHN-NNISINAHLEVYNRTVILKPPEDLLILRGTSVLLPCKF 509 Query: 315 -TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373 T P+ + W +G + + + +KY F L ++D +DS C Sbjct: 510 STDPRLPKAQVVWKKDGIK--LMESKAANKYS----FLDTDTLIVSDVQFSDSA-PYSCE 562 Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411 ++ G +TV D P + + ++ +L + Sbjct: 563 VISALDHVTATGSITVVDRPDPPKHLFLSEVTDDSLTL 600 Score = 38.3 bits (85), Expect = 1.3 Identities = 27/95 (28%), Positives = 42/95 (44%), Gaps = 8/95 (8%) Query: 382 FVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN 441 F +G + + D +PP +++ P + T PC A P P W +G+ + Sbjct: 38 FAQGAIEIPKDLSQPP-VLSEVPKSLTAFSLEDISLPCEATGNPPPTFEWVKDGQRI--- 93 Query: 442 HRRNVTNDGTLVLK--DLDKSDSGTYTCVASSRHG 474 R+ GTL K DL + G Y C AS+ +G Sbjct: 94 --RSDLASGTLQAKEDDLLQQFEGHYRCYASNIYG 126 >UniRef50_UPI0000F2E6F1 Cluster: PREDICTED: similar to L1 cell adhesion molecule; n=1; Monodelphis domestica|Rep: PREDICTED: similar to L1 cell adhesion molecule - Monodelphis domestica Length = 1344 Score = 144 bits (349), Expect = 1e-32 Identities = 132/483 (27%), Positives = 198/483 (40%), Gaps = 37/483 (7%) Query: 10 EAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI---LPAGG 65 + P I EQ P + V L C A G P RW K + + + +G Sbjct: 123 QPPNITEQSPEKLVVFPTDDIVLKCEASGKPEVQFRWTKENIHFSPEKELGATTHINSGS 182 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 T G Y C A+N GTA S L + + + + + +G +V Sbjct: 183 FIITGNTSNFAQRYQGTYRCFASNRLGTAMSHEIHLVAEGAPKWPKEKVQPFEVEEGQSV 242 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARN 184 VL C PP + +P +YW N + D R+ + GNL + D+ Y C A Sbjct: 243 VLPCNPPASAVQPRIYWM-NSRIFHIAQDERVTMGQNGNLYFANVLTNDSHSDYICHAHF 301 Query: 185 AAGTRESAIATLKIHIKPY--------LITGPEDV----VAQTGSSVTFQCRVGGDPLPD 232 + + +KP + PE + VA G + +C G P P Sbjct: 302 LGARTIMQKEPIDLRVKPTNNMIYRRPRLLLPEGLTSRLVALRGQPLVLECIAEGFPTPT 361 Query: 233 VLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291 + W S M GRV + + +LRL V D+GEY C AEN++G+ Y+TV Sbjct: 362 IKW--SYPSNQMQAGRVTYQNFNKTLRLVRVEEEDDGEYRCWAENTLGSAQHVYYVTVEA 419 Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 P P S+ + G AR C GRP P + W + G + ++RD V Sbjct: 420 APYWLQEPESLVLAPGETARLNCQVQGRPRPMVTWRING---VSLENLTRD--DKLRVQG 474 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL-P 410 G +L ++ ND+ T C A N G ++V P I+T P N+T Sbjct: 475 GALIL--SNVQPNDTMVT-QCEARNKHGLLLANAYISVV---QLPTKILT--PDNKTYRE 526 Query: 411 IK-SMAVFPCTAICTPEPIIAWYFEGEA-LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468 ++ S A C A P P I W +A ++Q+ R +GTL ++DL +D+G+Y C Sbjct: 527 VQGSTAYLLCNAFGVPMPSIQWLNRDQATVLQDERFVPYANGTLAIRDLQTNDTGSYFCQ 586 Query: 469 ASS 471 A + Sbjct: 587 ADN 589 Score = 143 bits (346), Expect = 3e-32 Identities = 198/849 (23%), Positives = 316/849 (37%), Gaps = 93/849 (10%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSP-SPAIRWYKGGVLVVSDTHRSILPAG 64 V G + E+ V Q L C S P I W + ++ R + Sbjct: 219 VAEGAPKWPKEKVQPFEVEEGQSVVLPCNPPASAVQPRIYWMNSRIFHIAQDERVTMGQN 278 Query: 65 G-LFFLRATHGRVHSDAGVYWCEA--TNSYGTARSRNATLHVA-----VLREEFRLEPES 116 G L+F HSD Y C A + + L V + R L PE Sbjct: 279 GNLYFANVLTNDSHSD---YICHAHFLGARTIMQKEPIDLRVKPTNNMIYRRPRLLLPEG 335 Query: 117 KQSA----QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ 172 S +G +VLEC+ G P P + W + + + L + + Sbjct: 336 LTSRLVALRGQPLVLECIA-EGFPTPTIKWSYPSNQMQAGRVTYQNF--NKTLRLVRVEE 392 Query: 173 TDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232 D G Y+C A N G+ + + + + PY + PE +V G + C+V G P P Sbjct: 393 EDDGEYRCWAENTLGSAQH-VYYVTVEAAPYWLQEPESLVLAPGETARLNCQVQGRPRPM 451 Query: 233 VLWR-RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291 V WR N+ + G+L L NV D CEA N G + A+ Y++V Sbjct: 452 VTWRINGVSLENLTRDDKLRVQGGALILSNVQPNDTMVTQCEARNKHGLLLANAYISVVQ 511 Query: 292 PPSINLSPNSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349 P+ L+P++ G+ A C A G P P++ W T++ +++ A Sbjct: 512 LPTKILTPDNKTYREVQGSTAYLLCNAFGVPMPSIQWLNRDQATVL----QDERFVPYA- 566 Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409 +G L I D ND+ + C A N ++ L V I GP ++T+ Sbjct: 567 -NGT--LAIRDLQTNDT-GSYFCQADNDQNRVSIKAHLQVKEATQ-----IKKGPEDRTV 617 Query: 410 PIKSMAVFPCTAICTPEPIIA--WYFEGEALIQNHRRN--VTNDGTLVLKDLDKSDSGTY 465 S FPC P I WY+ + + ++ + + + L + LD +D G Y Sbjct: 618 KKGSNVNFPCLVSFDPSLNIQIDWYWNDQNIKDFYKEDKYLIKEEELTIISLDYADQGNY 677 Query: 466 TCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWS 525 +CVA + +LV V S PGP + + D V LSWS Sbjct: 678 SCVAKTALDSVEKKATVLV---------------VGS-PGPVGQLELYKQKDFHVQLSWS 721 Query: 526 QNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMF 585 + +S I Y +E R G W +A L P + Y F Sbjct: 722 PAEE-HNSPIEKYNIEFEDRTMEPGT--------WYPLATVPGNETSTRLKLSPFVHYNF 772 Query: 586 IVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPID 645 V N G S PSP S+ + S T V NN++ Sbjct: 773 RVIANNKFGASEPSPDSEPF-ITPKSVPEKNPTNVKGEGNETNNMV-------------- 817 Query: 646 SKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEF 705 + W+ L + G + +R E E + ++ S + +++ + YE Sbjct: 818 -----ITWKPLKWIDWNGPELKYRVQWRQKNESEWREVMVR--ASKYVVSNTPTFVPYEI 870 Query: 706 FLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIIT 765 + + +G + + + +DVP PI + + +LN TTV +KW P +L G + Sbjct: 871 KVQAINEVGKGPDPHIVIGYSGEDVPQAIPI-VAIELLNATTVRIKWEPVDLNEVRGHLR 929 Query: 766 GYNVVVNWLDVPANKSMVAINTTV----HQATSLIMTNLTSGVSYSVQIAAETIIGLGPF 821 GY V W++ ++S T+ A ++ +L YSV + LGP Sbjct: 930 GYRVTYWWVNSRWSRSKRHTPKTIIDKPASAMEAVLPDLRPYSIYSVHVQVFNSRSLGPP 989 Query: 822 SQKVYFNID 830 S+ + F + Sbjct: 990 SETIKFETE 998 Score = 106 bits (254), Expect = 4e-21 Identities = 88/295 (29%), Positives = 131/295 (44%), Gaps = 14/295 (4%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA- 63 YVT APY +++P + +A + A LNC+ G P P + W GV + + T L Sbjct: 414 YVTVEAAPYWLQEPESLVLAPGETARLNCQVQGRPRPMVTWRINGVSLENLTRDDKLRVQ 473 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQ 121 GG L +D V CEA N +G + NA + V L + L P++K + Q Sbjct: 474 GGALILSNVQ---PNDTMVTQCEARNKHGLLLA-NAYISVVQLPTKI-LTPDNKTYREVQ 528 Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181 G T L C G P P++ W Q + D R G L I+D + D G Y C Sbjct: 529 GSTAYLLC-NAFGVPMPSIQWLNRDQATVLQ-DERFVPYANGTLAIRDLQTNDTGSYFCQ 586 Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL--WRRSA 239 A N R S A L++ + GPED + GS+V F C V DP ++ W + Sbjct: 587 ADNDQ-NRVSIKAHLQVKEATQIKKGPEDRTVKKGSNVNFPCLVSFDPSLNIQIDWYWND 645 Query: 240 GGGNMPLGRVK-VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293 K ++ + L + ++ AD+G YSC A+ ++ +V + V P Sbjct: 646 QNIKDFYKEDKYLIKEEELTIISLDYADQGNYSCVAKTALDSVEKKATVLVVGSP 700 Score = 41.9 bits (94), Expect = 0.10 Identities = 35/129 (27%), Positives = 56/129 (43%), Gaps = 10/129 (7%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753 + LR Y+ Y + F + G PS + +T + VPD P ++ + L+ T + L W Sbjct: 965 LPDLRPYSIYSVHVQVFNSRSLGPPSETIKFETEEGVPDRPQ-SLNLRRLSDTALQLSWR 1023 Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTS---GVSYSVQI 810 PP NG + GY ++ P N+ T + +M NL+ Y Q+ Sbjct: 1024 PP--LNPNGELKGYQLIYR----PFNQEPEENEMTEFLPPTTLMFNLSDLKPQTLYRFQL 1077 Query: 811 AAETIIGLG 819 A T +G G Sbjct: 1078 RATTKVGPG 1086 >UniRef50_UPI0000F1EDBC Cluster: PREDICTED: similar to adlican; n=1; Danio rerio|Rep: PREDICTED: similar to adlican - Danio rerio Length = 1903 Score = 144 bits (348), Expect = 2e-32 Identities = 132/476 (27%), Positives = 210/476 (44%), Gaps = 36/476 (7%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWY---KGGVLVVSDTHRSI-LPAGGLFFLRATHGR 75 DVTV A L C+A G P P I W + + VS+T + I L A G ++ T+ Sbjct: 1035 DVTVYIGNTALLQCQAQGLPIPNISWMLPDRSMLRSVSNTQQKIMLLANGTLQIKQTN-- 1092 Query: 76 VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVLECLPPRG 134 + D GVY C A+N+ G A + L + L + + E+ + G ++ C G Sbjct: 1093 -YLDTGVYKCIASNAAG-ADMLSVRLQITALAPVIQEQRWENYTLSDGHAALIHCTA-NG 1149 Query: 135 SPEPNVYWKKNGQTLLFDG---DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191 +P P V W + L +S + + G L I++ D+G Y+C+A ++ G + Sbjct: 1150 APNPTVRWVTSSGMQLRPSQFVNSNLFVFPNGTLFIRNPTVKDSGIYECVAVSSVGMAKR 1209 Query: 192 AIATLKIHIKP----YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG---GGNM 244 ++ L++ L T G ++ C G P P ++WR A Sbjct: 1210 SV-NLQVKRNSGSARILSTSAHSTDVHYGDQLSLNCSASGSPTPRIIWRTPAKKLVDSYY 1268 Query: 245 PLGR-VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS--INLSPNS 301 R +KVL +G+L + +V DEGEY C A N+ G +TV + + S + Sbjct: 1269 SFDRRMKVLSNGTLTITSVTEQDEGEYLCAARNNAGDDYVLLKVTVMMKAAKIDHKSLSE 1328 Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA----VFDGVTVLT 357 V G + C A+G P P + WS+ + T+I +S DK A +FD T L Sbjct: 1329 HKVLYGGELKVDCIASGLPNPEVSWSLP-DGTMINSVLSSDKNTIRAKRYVMFDNGT-LY 1386 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417 +N+ + C A N G ++ + V +D P I N S + A+ Sbjct: 1387 LNEVGMKE-EGDYTCYAKNQMGKDEMKVHIKVLAD---APVIRNNAYSVIKVTYGETAIL 1442 Query: 418 PCTAICTPEPIIAWYFEGEALI--QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471 C+A P P+I W + +I ++ ++NDGTL + K +SG YTC+A S Sbjct: 1443 NCSAKGEPTPVITWISPDKKVIVPMTNKYQISNDGTLHIHKTQKINSGNYTCMARS 1498 Score = 134 bits (324), Expect = 1e-29 Identities = 145/606 (23%), Positives = 245/606 (40%), Gaps = 54/606 (8%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI----LPAGGLFFLRATHGRV 76 V+V L C + G P P + W K V T+ + + G F +R H + Sbjct: 939 VSVNAGTDVQLPCNSVGEPRPLLTWTKVSTGAVMSTNTKVQRFEVHPNGTFTIRNVHLQ- 997 Query: 77 HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136 D G Y C A+N++GT + + +A + + G+T +L+C +G P Sbjct: 998 --DRGQYLCSASNAHGTDKMMVTLVVLAHVPRMTSPRHQDVTVYIGNTALLQC-QAQGLP 1054 Query: 137 EPNVYWKKNGQTLL---FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193 PN+ W +++L + ++ L+ G L I+ D G Y+CIA NAAG ++ Sbjct: 1055 IPNISWMLPDRSMLRSVSNTQQKIMLLANGTLQIKQTNYLDTGVYKCIASNAAGADMLSV 1114 Query: 194 ATLKIHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK-- 250 + P + E+ G + C G P P V W S+G P V Sbjct: 1115 RLQITALAPVIQEQRWENYTLSDGHAALIHCTANGAPNPTVRWVTSSGMQLRPSQFVNSN 1174 Query: 251 --VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY----DPPSINLSPNSVNV 304 V +G+L + N + D G Y C A +SVG S L V ++ S +S +V Sbjct: 1175 LFVFPNGTLFIRNPTVKDSGIYECVAVSSVGMAKRSVNLQVKRNSGSARILSTSAHSTDV 1234 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 G+ C+A+G P P + W + ++ S D+ +T+ ++ + D+ Sbjct: 1235 HYGDQLSLNCSASGSPTPRIIWRTPAKK-LVDSYYSFDRRMKVLSNGTLTITSVTEQDEG 1293 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424 + +C+A N AG +V K+TV + I S + C A Sbjct: 1294 E----YLCAARNNAGDDYVLLKVTVMM---KAAKIDHKSLSEHKVLYGGELKVDCIASGL 1346 Query: 425 PEPIIAWYFEGEALIQN-----------HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473 P P ++W +I + R + ++GTL L ++ + G YTC A ++ Sbjct: 1347 PNPEVSWSLPDGTMINSVLSSDKNTIRAKRYVMFDNGTLYLNEVGMKEEGDYTCYAKNQM 1406 Query: 474 GKYVWSG--ALLVDSPINPN-------IHFFRAADVS-SLPGPPTKPITHNVTDTSVTLS 523 GK +L D+P+ N + + A ++ S G PT IT D V + Sbjct: 1407 GKDEMKVHIKVLADAPVIRNNAYSVIKVTYGETAILNCSAKGEPTPVITWISPDKKVIVP 1466 Query: 524 WSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVV-KSLIPGIT 582 + +I + L + + ++ N +R V I R+V +V +I G Sbjct: 1467 MTNKYQISNDGTL----HIHKTQKINSGNYTCMARSVVGIDRKVVLVEVLVFPPVINGFE 1522 Query: 583 YMFIVR 588 + I+R Sbjct: 1523 HPGIIR 1528 Score = 120 bits (289), Expect = 2e-25 Identities = 125/497 (25%), Positives = 195/497 (39%), Gaps = 47/497 (9%) Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-----DTHRSILP 62 SG A + V +LNC A GSP+P I W +V D +L Sbjct: 1219 SGSARILSTSAHSTDVHYGDQLSLNCSASGSPTPRIIWRTPAKKLVDSYYSFDRRMKVLS 1278 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ- 121 G L T D G Y C A N+ G L V V+ + +++ +S + Sbjct: 1279 NGTLTITSVT----EQDEGEYLCAARNNAG---DDYVLLKVTVMMKAAKIDHKSLSEHKV 1331 Query: 122 --GDTVVLECLPPRGSPEPNVYWKKNGQTLL---FDGD------SRMHLVDGGNLVIQDA 170 G + ++C+ G P P V W T++ D R + D G L + + Sbjct: 1332 LYGGELKVDCI-ASGLPNPEVSWSLPDGTMINSVLSSDKNTIRAKRYVMFDNGTLYLNEV 1390 Query: 171 RQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDP 229 + G Y C A+N G E + + P + V+ T G + C G+P Sbjct: 1391 GMKEEGDYTCYAKNQMGKDEMKVHIKVLADAPVIRNNAYSVIKVTYGETAILNCSAKGEP 1450 Query: 230 LPDVLWRRSAGGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288 P + W +P+ + ++ +DG+L + + G Y+C A + VG + Sbjct: 1451 TPVITWISPDKKVIVPMTNKYQISNDGTLHIHKTQKINSGNYTCMARSVVGIDRKVVLVE 1510 Query: 289 V-YDPPSIN--LSPNSVNVESGNVAR--FTCTATGRPEPTMFWSVEGNRTIIFPGM-SRD 342 V PP IN P + + R F C A G P P + W N + P SR Sbjct: 1511 VLVFPPVINGFEHPGIIRKTAVRDQRVLFDCKANGNPFPRIIWLFPNNVVLPAPYYGSRI 1570 Query: 343 KYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN 402 H D + + ++D+ + ++C A N G + + KL VT D +P + N Sbjct: 1571 TVHRNGTLD-IHAVRMSDSVE------LICIARNEFGETKLHVKLEVTEDIIKPQ--LRN 1621 Query: 403 GPSNQ-TLPIKSMAVFPCTAICTPEPIIAWYF-EGEALIQN---HRRNVTNDGTLVLKDL 457 P++ L I C+ P P I W G +L Q R + +DG L++K+ Sbjct: 1622 SPTDSIQLTIGKPTTLNCSIEGNPAPQITWTLPNGTSLYQGTTFSRFHHRSDGALLIKEP 1681 Query: 458 DKSDSGTYTCVASSRHG 474 SD+G Y CV + G Sbjct: 1682 SSSDAGLYRCVGRNSGG 1698 Score = 117 bits (281), Expect = 2e-24 Identities = 114/481 (23%), Positives = 204/481 (42%), Gaps = 43/481 (8%) Query: 31 LNCRAGGSPSPAIRW-YKGGVL---VVSDTHRSILPAGGLFFLRAT---HGRVHSDAGVY 83 ++C A G P+P + W G + V+S +I + F T + + G Y Sbjct: 1339 VDCIASGLPNPEVSWSLPDGTMINSVLSSDKNTIRAKRYVMFDNGTLYLNEVGMKEEGDY 1398 Query: 84 WCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GDTVVLECLPPRGSPEPNV 140 C A N G + +H+ VL + + + + G+T +L C +G P P + Sbjct: 1399 TCYAKNQMGKDEMK---VHIKVLADAPVIRNNAYSVIKVTYGETAILNC-SAKGEPTPVI 1454 Query: 141 YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200 W + ++ ++ + + G L I ++ ++G Y C+AR+ G + + +++ + Sbjct: 1455 TWISPDKKVIVPMTNKYQISNDGTLHIHKTQKINSGNYTCMARSVVGI-DRKVVLVEVLV 1513 Query: 201 KPYLITGPE--DVVAQTG---SSVTFQCRVGGDPLPDVLWRRSAGGGNMPL----GRVKV 251 P +I G E ++ +T V F C+ G+P P ++W +P R+ V Sbjct: 1514 FPPVINGFEHPGIIRKTAVRDQRVLFDCKANGNPFPRIIW-LFPNNVVLPAPYYGSRITV 1572 Query: 252 LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLSP-NSVNVESG 307 +G+L + V ++D E C A N G L V + P + SP +S+ + G Sbjct: 1573 HRNGTLDIHAVRMSDSVELICIARNEFGETKLHVKLEVTEDIIKPQLRNSPTDSIQLTIG 1632 Query: 308 NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367 C+ G P P + W++ N T ++ G + ++H + DG L I + +D+ Sbjct: 1633 KPTTLNCSIEGNPAPQITWTLP-NGTSLYQGTTFSRFHHRS--DG--ALLIKEPSSSDA- 1686 Query: 368 NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427 C N G FV +T+ S +R P I S ++ C + P P Sbjct: 1687 GLYRCVGRNSGG--FVERNVTLVS--NRKPEITNQYSSLLSIINGEDLHLDCVSDAHPPP 1742 Query: 428 IIAWYFEGEALI----QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483 + W ++ + R +V N+GTL + D GTY C S+ HG S +++ Sbjct: 1743 KLTWTLPSGVVLSRAQSSGRHSVLNNGTLSIHRTSVYDRGTYRCQISNDHGSSSLSVSVI 1802 Query: 484 V 484 V Sbjct: 1803 V 1803 Score = 109 bits (262), Expect = 5e-22 Identities = 125/485 (25%), Positives = 197/485 (40%), Gaps = 38/485 (7%) Query: 10 EAPYIIEQPLDVT-VARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLF 67 +AP I V V + A LNC A G P+P I W ++V T++ + G Sbjct: 1420 DAPVIRNNAYSVIKVTYGETAILNCSAKGEPTPVITWISPDKKVIVPMTNKYQISNDGTL 1479 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR---EEFRLEPESKQSAQGDT 124 + T +++S G Y C A + G R + + V V F +++A D Sbjct: 1480 HIHKTQ-KINS--GNYTCMARSVVGIDR-KVVLVEVLVFPPVINGFEHPGIIRKTAVRDQ 1535 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLL---FDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181 VL G+P P + W +L + G SR+ + G L I R +D+ CI Sbjct: 1536 RVLFDCKANGNPFPRIIWLFPNNVVLPAPYYG-SRITVHRNGTLDIHAVRMSDSVELICI 1594 Query: 182 ARNAAGTRESAIA--TLKIHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRS 238 ARN G + + + IKP L P D + T G T C + G+P P + W Sbjct: 1595 ARNEFGETKLHVKLEVTEDIIKPQLRNSPTDSIQLTIGKPTTLNCSIEGNPAPQITWTLP 1654 Query: 239 AGGG---NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295 G R DG+L + +D G Y C NS G V + L P I Sbjct: 1655 NGTSLYQGTTFSRFHHRSDGALLIKEPSSSDAGLYRCVGRNSGGFVERNVTLVSNRKPEI 1714 Query: 296 -NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354 N + +++ +G C + P P + W++ ++ S ++ +V + T Sbjct: 1715 TNQYSSLLSIINGEDLHLDCVSDAHPPPKLTWTLPSG-VVLSRAQSSGRH---SVLNNGT 1770 Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414 L+I+ T D R T C N GSS + + V + PP IT+GP+ T + Sbjct: 1771 -LSIHRTSVYD-RGTYRCQISNDHGSSSLSVSVIVIAY----PPRITSGPAAVTYGRVGV 1824 Query: 415 AV-FPCTAICTPEPIIAWYF-EGEAL---IQNH---RRNVTNDGTLVLKDLDKSDSGTYT 466 A+ C ++ +P + W +G L +Q +++ G L + DSG Y Sbjct: 1825 ALTLDCRSLASPRAEVVWQMPDGLQLKVDVQPRLYGNKHLHPQGVLQIHSPSSRDSGVYK 1884 Query: 467 CVASS 471 C A + Sbjct: 1885 CTAKN 1889 Score = 103 bits (246), Expect = 4e-20 Identities = 96/371 (25%), Positives = 150/371 (40%), Gaps = 19/371 (5%) Query: 22 TVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80 T R Q +C+A G+P P I W + V++ + + S + L H SD+ Sbjct: 1530 TAVRDQRVLFDCKANGNPFPRIIWLFPNNVVLPAPYYGSRITVHRNGTLDI-HAVRMSDS 1588 Query: 81 GVYWCEATNSYGTARSRNATLHVA--VLREEFRLEP-ESKQSAQGDTVVLECLPPRGSPE 137 C A N +G + + L V +++ + R P +S Q G L C G+P Sbjct: 1589 VELICIARNEFGETKL-HVKLEVTEDIIKPQLRNSPTDSIQLTIGKPTTLNC-SIEGNPA 1646 Query: 138 PNVYWKKNGQTLLFDGD--SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195 P + W T L+ G SR H G L+I++ +DAG Y+C+ RN+ G E + T Sbjct: 1647 PQITWTLPNGTSLYQGTTFSRFHHRSDGALLIKEPSSSDAGLYRCVGRNSGGFVERNV-T 1705 Query: 196 LKIHIKPYLITGPEDVVA-QTGSSVTFQCRVGGDPLPDVLWRRSAG---GGNMPLGRVKV 251 L + KP + +++ G + C P P + W +G GR V Sbjct: 1706 LVSNRKPEITNQYSSLLSIINGEDLHLDCVSDAHPPPKLTWTLPSGVVLSRAQSSGRHSV 1765 Query: 252 LDDGSLRLDNVILADEGEYSCEAENSVGAVSAS-GYLTVYDPPSINLSPNSVNVESGNVA 310 L++G+L + + D G Y C+ N G+ S S + + PP I P +V VA Sbjct: 1766 LNNGTLSIHRTSVYDRGTYRCQISNDHGSSSLSVSVIVIAYPPRITSGPAAVTYGRVGVA 1825 Query: 311 -RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369 C + P + W + + R + VL I+ DS Sbjct: 1826 LTLDCRSLASPRAEVVWQMPDGLQLKVDVQPR--LYGNKHLHPQGVLQIHSPSSRDS-GV 1882 Query: 370 IVCSAVNYAGS 380 C+A N GS Sbjct: 1883 YKCTAKNVLGS 1893 Score = 88.6 bits (210), Expect = 9e-16 Identities = 80/293 (27%), Positives = 126/293 (43%), Gaps = 20/293 (6%) Query: 12 PYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILP--AGGLF 67 P + P D + + +P TLNC G+P+P I W G + T S + G Sbjct: 1617 PQLRNSPTDSIQLTIGKPTTLNCSIEGNPAPQITWTLPNGTSLYQGTTFSRFHHRSDGAL 1676 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVV 126 ++ SDAG+Y C NS G RN TL V+ + E + S S G+ + Sbjct: 1677 LIKEPSS---SDAGLYRCVGRNSGGFVE-RNVTL-VSNRKPEITNQYSSLLSIINGEDLH 1731 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDS--RMHLVDGGNLVIQDARQTDAGRYQCIARN 184 L+C+ P P + W +L S R +++ G L I D G Y+C N Sbjct: 1732 LDCVSD-AHPPPKLTWTLPSGVVLSRAQSSGRHSVLNNGTLSIHRTSVYDRGTYRCQISN 1790 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSAG--- 240 G+ +++ + I P + +GP V + G ++T CR P +V+W+ G Sbjct: 1791 DHGSSSLSVSVIVIAYPPRITSGPAAVTYGRVGVALTLDCRSLASPRAEVVWQMPDGLQL 1850 Query: 241 -GGNMP--LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290 P G + G L++ + D G Y C A+N +G+ S S Y+ V+ Sbjct: 1851 KVDVQPRLYGNKHLHPQGVLQIHSPSSRDSGVYKCTAKNVLGSDSRSTYVYVF 1903 Score = 54.4 bits (125), Expect = 2e-05 Identities = 44/182 (24%), Positives = 80/182 (43%), Gaps = 17/182 (9%) Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPG--MSRDKYHATAVFDGVTVLT 357 ++V+V +G + C + G P P + W+ ++ + R + H F T Sbjct: 937 HTVSVNAGTDVQLPCNSVGEPRPLLTWTKVSTGAVMSTNTKVQRFEVHPNGTF------T 990 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417 I + D R +CSA N G+ + L V + P + + + T+ I + A+ Sbjct: 991 IRNVHLQD-RGQYLCSASNAHGTDKMMVTLVVLA---HVPRMTSPRHQDVTVYIGNTALL 1046 Query: 418 PCTAICTPEPIIAWYFEGEAL---IQNHRRNV--TNDGTLVLKDLDKSDSGTYTCVASSR 472 C A P P I+W ++ + N ++ + +GTL +K + D+G Y C+AS+ Sbjct: 1047 QCQAQGLPIPNISWMLPDRSMLRSVSNTQQKIMLLANGTLQIKQTNYLDTGVYKCIASNA 1106 Query: 473 HG 474 G Sbjct: 1107 AG 1108 >UniRef50_Q4RVM2 Cluster: Chromosome 9 SCAF14991, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 9 SCAF14991, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1049 Score = 144 bits (348), Expect = 2e-32 Identities = 131/459 (28%), Positives = 197/459 (42%), Gaps = 35/459 (7%) Query: 44 RWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103 RW G L+ R +GG + + + D G+Y C A N+ G SR A+L Sbjct: 91 RWSLNGTLINLGLDRRRRLSGGNLIISSLDR--YQDVGMYQCMAFNTAGAILSRRASLQF 148 Query: 104 AVLREEFRLEPESKQSA-QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG 162 A L + F++ S S +G VVL C P S + W N D+R + Sbjct: 149 AYL-DHFKVHTRSAVSVREGQGVVLLCGTPTSSGDLAYAWVFNEYPYFVQQDNRRFVSQQ 207 Query: 163 -GNLVIQDARQTDAGRYQCIARNAA--GTRESAIATLKIHI-------KPYL-ITGPEDV 211 GNL I +D G Y C+ N+ G +S+ L + +P + + P++V Sbjct: 208 TGNLYIAKVEPSDVGNYTCVVTNSVTKGKVQSSPTALILRTDGMMGEYEPKIEVNFPDNV 267 Query: 212 VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV-LDDGSLRLDNVILADEGEY 270 A GS+VT +C G+P+P++ W+R A G P +VK+ + L + + D G Y Sbjct: 268 SAARGSTVTLECFALGNPVPEITWKR-ANGVPFP-SKVKMKYSNAVLEIPSFQQDDTGGY 325 Query: 271 SCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330 C AEN +G A+G L Y P + + + C A G+P+P+ W G Sbjct: 326 ECVAENRMGKNMATGRLAFYAKPQWIQAVKDTALAIEERLHWECRANGKPKPSYAWLKNG 385 Query: 331 NRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT 390 + + S D+ V DGV L++ +D+ C A N G + +L V Sbjct: 386 QQLL-----SGDRI---TVEDGV--LSVPALALSDA-GMYQCVAENKHGVIYFVAELMVL 434 Query: 391 SDDDRPPPIITNGPSNQTLPIKS--MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN 448 + PP T L K+ C P I W + N R +++ Sbjct: 435 AS----PPDFTGNLLRALLKAKAGTTVTLECKPQAYPVASILWKKGNLPIHINDRITLSS 490 Query: 449 DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 DGTL L ++ KSD+G YTC A +R G +G LLV P Sbjct: 491 DGTLRLANVSKSDAGGYTCFARNRFGMSSTTGRLLVTDP 529 Score = 142 bits (344), Expect = 5e-32 Identities = 149/544 (27%), Positives = 225/544 (41%), Gaps = 63/544 (11%) Query: 78 SDAGVYWCEATNSY--GTARSRNATLHV---AVLRE-EFRLE---PESKQSAQGDTVVLE 128 SD G Y C TNS G +S L + ++ E E ++E P++ +A+G TV LE Sbjct: 219 SDVGNYTCVVTNSVTKGKVQSSPTALILRTDGMMGEYEPKIEVNFPDNVSAARGSTVTLE 278 Query: 129 CLPPRGSPEPNVYWKK-NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 C G+P P + WK+ NG + F +M L I +Q D G Y+C+A N G Sbjct: 279 CFA-LGNPVPEITWKRANG--VPFPSKVKMKY-SNAVLEIPSFQQDDTGGYECVAENRMG 334 Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247 + A L + KP I +D + ++CR G P P W ++ G + G Sbjct: 335 -KNMATGRLAFYAKPQWIQAVKDTALAIEERLHWECRANGKPKPSYAWLKN--GQQLLSG 391 Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-DPPSI--NLSPNSVNV 304 ++DG L + + L+D G Y C AEN G + L V PP NL + Sbjct: 392 DRITVEDGVLSVPALALSDAGMYQCVAENKHGVIYFVAELMVLASPPDFTGNLLRALLKA 451 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 ++G C P ++ W +GN P D+ T DG L + + K+ Sbjct: 452 KAGTTVTLECKPQAYPVASILWK-KGN----LPIHINDRI--TLSSDGT--LRLANVSKS 502 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424 D+ C A N G S G+L VT P IT GP++ + + V PC Sbjct: 503 DAGG-YTCFARNRFGMSSTTGRLLVTD-----PTRITQGPADMEIIVGESIVLPCQVASD 556 Query: 425 P--EPIIAWYFEGEALIQN--HRRNV--TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVW 478 P + +W F G+ + + H V G L+++++ +G Y CV + Sbjct: 557 PVLDVSFSWAFNGQLIAKGDGHFELVGGRTAGDLMIRNIQLYHAGKYICVVDTDVESLSA 616 Query: 479 SGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGY 538 L+V P P PP VTD++ L+WS+ G S I+ Y Sbjct: 617 VAILIVKGP----------------PSPPDSVTVEEVTDSTAQLAWSRGRDNG-SPIVNY 659 Query: 539 QVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598 V+ + T+ N+ ++ + T V L + Y F V NS G+ P Sbjct: 660 FVQTRTPFTVGWQRV--NTVPEIIDGNTLTAT---VVDLNAWVEYEFRVLARNSVGVGEP 714 Query: 599 SPVS 602 SPVS Sbjct: 715 SPVS 718 Score = 113 bits (272), Expect = 3e-23 Identities = 97/322 (30%), Positives = 141/322 (43%), Gaps = 25/322 (7%) Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAGGLFFLRATHGRV 76 P +V+ AR TL C A G+P P I W + GV S A + Sbjct: 264 PDNVSAARGSTVTLECFALGNPVPEITWKRANGVPFPSKVKMKYSNA-----VLEIPSFQ 318 Query: 77 HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136 D G Y C A N G + A + ++ + A + + EC G P Sbjct: 319 QDDTGGYECVAENRMGKNMATGRLAFYA--KPQWIQAVKDTALAIEERLHWECRA-NGKP 375 Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196 +P+ W KNGQ LL GD R+ V+ G L + +DAG YQC+A N G +A L Sbjct: 376 KPSYAWLKNGQQLL-SGD-RI-TVEDGVLSVPALALSDAGMYQCVAENKHGVIYF-VAEL 431 Query: 197 KIHIKPYLITGP---EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL---GRVK 250 + P TG + A+ G++VT +C+ P+ +LW++ GN+P+ R+ Sbjct: 432 MVLASPPDFTGNLLRALLKAKAGTTVTLECKPQAYPVASILWKK----GNLPIHINDRIT 487 Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310 + DG+LRL NV +D G Y+C A N G S +G L V DP I P + + G Sbjct: 488 LSSDGTLRLANVSKSDAGGYTCFARNRFGMSSTTGRLLVTDPTRITQGPADMEIIVGESI 547 Query: 311 RFTCTATGRP--EPTMFWSVEG 330 C P + + W+ G Sbjct: 548 VLPCQVASDPVLDVSFSWAFNG 569 Score = 107 bits (258), Expect = 1e-21 Identities = 92/301 (30%), Positives = 130/301 (43%), Gaps = 20/301 (6%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I+ D +A + CRA G P P+ W K G ++S I G+ + A Sbjct: 348 PQWIQAVKDTALAIEERLHWECRANGKPKPSYAWLKNGQQLLSGDR--ITVEDGVLSVPA 405 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEF--RLEPESKQSAQGDTVVLEC 129 SDAG+Y C A N +G A L V +F L ++ G TV LEC Sbjct: 406 L---ALSDAGMYQCVAENKHGVIYF-VAELMVLASPPDFTGNLLRALLKAKAGTTVTLEC 461 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189 P+ P ++ WKK L + R+ L G L + + ++DAG Y C ARN G Sbjct: 462 -KPQAYPVASILWKKG--NLPIHINDRITLSSDGTLRLANVSKSDAGGYTCFARNRFG-M 517 Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-----GNM 244 S L + + GP D+ G S+ C+V DP+ DV + + G G+ Sbjct: 518 SSTTGRLLVTDPTRITQGPADMEIIVGESIVLPCQVASDPVLDVSFSWAFNGQLIAKGDG 577 Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304 V G L + N+ L G+Y C + V ++SA L V PPS P+SV V Sbjct: 578 HFELVGGRTAGDLMIRNIQLYHAGKYICVVDTDVESLSAVAILIVKGPPS---PPDSVTV 634 Query: 305 E 305 E Sbjct: 635 E 635 >UniRef50_A4JYE0 Cluster: CDNA, clone cssl:d0205; n=2; Danio rerio|Rep: CDNA, clone cssl:d0205 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 744 Score = 144 bits (348), Expect = 2e-32 Identities = 151/555 (27%), Positives = 235/555 (42%), Gaps = 52/555 (9%) Query: 10 EAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGL 66 + P I++Q L D V + C A G+P P +W + G V D ++ G Sbjct: 40 QPPTIVKQSLKDYIVDPRDNIIIECEAKGNPVPTFQWRRNGKFFNVGKDPRVTMRSRSGT 99 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV--LREEFRLEPESKQSAQGDT 124 +R++ G+ G Y C A+N+ GTA S L V+ L + LEP + + +G Sbjct: 100 LEIRSS-GKPEDYEGEYQCFASNNLGTAISNKILLRVSKSPLWPKEVLEPVTVR--EGSP 156 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIAR 183 +VL C PP G P P +W + + D R+ + G+L + DA Y C AR Sbjct: 157 LVLACNPPPGLPPPETFW-MDSFIMPIAQDRRVSMGLNGDLFFSNVLAKDAKTDYSCNAR 215 Query: 184 --NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVT----------FQCRVGGDPLP 231 ++ TLK+ + ++ TG S T +C G P P Sbjct: 216 FEFTHTIQQKNPYTLKVQTMRNIPETQPTFLSPTGLSSTKMVLRGEELLLECIAAGVPTP 275 Query: 232 DVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290 + W S GG++P +V++ + D +LR+ NV D G Y+C A N +G++ + + V Sbjct: 276 TITW--SKRGGDLPTKKVRIGNFDKTLRILNVSEEDIGSYTCMASNRIGSIRHTVEVQVK 333 Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR-TIIFPGMSRDKYHATAV 349 P P ++ + R C A G P+PT+ W V G P +R T + Sbjct: 334 AAPFWLEKPINLVLAPDESGRLVCRANGSPKPTIQWLVNGEPIESSLPNPNRRVLDDTII 393 Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409 F +T + +S C+A N G ++V D P ++ GP NQ + Sbjct: 394 F---------ETVQFESSAVYQCNASNEHGYLLANAFVSVL---DMAPRML--GPKNQLI 439 Query: 410 PI--KSMAVFPCTAICTPEPIIAWYFE--GEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465 + + C +P P++ W+ G L H R + ++GTL +K D GTY Sbjct: 440 KVIENNRTFLECPFFGSPLPLLRWFKNGLGSGLDGGHYR-LYHNGTLEIKQAQTEDQGTY 498 Query: 466 TCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVT-DTSV--TL 522 TCVAS GK L V P RA + + P T V D S+ T+ Sbjct: 499 TCVASIILGKMENQVRLEVKEP----TRIVRAPEHKTEPRGTTVRFDCRVKHDPSLPATV 554 Query: 523 SWSQNNKIGSSSILG 537 +W ++ K S S +G Sbjct: 555 TWLKDEKPLSFSWIG 569 Score = 116 bits (278), Expect = 5e-24 Identities = 94/301 (31%), Positives = 144/301 (47%), Gaps = 19/301 (6%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS---DTHRSILPAGGLF 67 AP+ +E+P+++ +A + L CRA GSP P I+W G + S + +R +L +F Sbjct: 335 APFWLEKPINLVLAPDESGRLVCRANGSPKPTIQWLVNGEPIESSLPNPNRRVLDDTIIF 394 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTV 125 + VY C A+N +G + NA + V + L P+++ + + + Sbjct: 395 -----ETVQFESSAVYQCNASNEHGYLLA-NAFVSVLDMAPRM-LGPKNQLIKVIENNRT 447 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 LEC P GSP P + W KNG DG L G L I+ A+ D G Y C+A Sbjct: 448 FLEC-PFFGSPLPLLRWFKNGLGSGLDG-GHYRLYHNGTLEIKQAQTEDQGTYTCVASII 505 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP-LP-DVLWRRSAGGGN 243 G E+ + L++ ++ PE G++V F CRV DP LP V W + + Sbjct: 506 LGKMENQV-RLEVKEPTRIVRAPEHKTEPRGTTVRFDCRVKHDPSLPATVTWLKDEKPLS 564 Query: 244 MP-LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302 +GR+K DD SL + NV D G Y+C A+ + +AS LTV + S + S S Sbjct: 565 FSWIGRLK-KDDESLTIYNVNPDDGGTYTCTAKTEIDEDTASARLTVTENDSSSASNRSA 623 Query: 303 N 303 + Sbjct: 624 S 624 Score = 111 bits (266), Expect = 1e-22 Identities = 145/603 (24%), Positives = 227/603 (37%), Gaps = 61/603 (10%) Query: 21 VTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPAGG-LFFLRATHGRVHS 78 VTV P L C G P P W ++ ++ R + G LFF + Sbjct: 149 VTVREGSPLVLACNPPPGLPPPETFWMDSFIMPIAQDRRVSMGLNGDLFFSNVLAKDAKT 208 Query: 79 DAGVYWCEATNSYG-TARSRNA-TLHVAVLREEFRLEP---------ESKQSAQGDTVVL 127 D Y C A + T + +N TL V +R +P +K +G+ ++L Sbjct: 209 D---YSCNARFEFTHTIQQKNPYTLKVQTMRNIPETQPTFLSPTGLSSTKMVLRGEELLL 265 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN----LVIQDARQTDAGRYQCIAR 183 EC+ G P P + W K G GD V GN L I + + D G Y C+A Sbjct: 266 ECIAA-GVPTPTITWSKRG------GDLPTKKVRIGNFDKTLRILNVSEEDIGSYTCMAS 318 Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-- 241 N G+ + +++ P+ + P ++V S CR G P P + W + Sbjct: 319 NRIGSIRHTVE-VQVKAAPFWLEKPINLVLAPDESGRLVCRANGSPKPTIQWLVNGEPIE 377 Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301 ++P +VLDD ++ + V Y C A N G + A+ +++V D L P + Sbjct: 378 SSLPNPNRRVLDD-TIIFETVQFESSAVYQCNASNEHGYLLANAFVSVLDMAPRMLGPKN 436 Query: 302 --VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359 + V N C G P P + W G G D H +G L I Sbjct: 437 QLIKVIENNRTFLECPFFGSPLPLLRWFKNGL------GSGLDGGHYRLYHNGT--LEIK 488 Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419 D + T C A G + +L V + P I P ++T P + F C Sbjct: 489 QAQTED-QGTYTCVASIILGKMENQVRLEV-----KEPTRIVRAPEHKTEPRGTTVRFDC 542 Query: 420 TAICTPE--PIIAWYFEGEALIQNH-RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476 P + W + + L + R +D +L + +++ D GTYTC A + + Sbjct: 543 RVKHDPSLPATVTWLKDEKPLSFSWIGRLKKDDESLTIYNVNPDDGGTYTCTAKTEIDED 602 Query: 477 VWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSIL 536 S L V N + + + P PP + + SV L+W N+ +S + Sbjct: 603 TASARLTVTE--NDSSSASNRSASAGRPDPPQDLELSDPSARSVRLTWVPGNE-NNSPVT 659 Query: 537 GYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596 + V+ G W ++ + V L P + Y F V N+ G S Sbjct: 660 HFLVQFEEDRWEPGK--------WQNLSIYDWNLNSVNLQLSPFVNYQFRVIAINAVGQS 711 Query: 597 GPS 599 PS Sbjct: 712 QPS 714 >UniRef50_P32004 Cluster: Neural cell adhesion molecule L1 precursor; n=68; Mammalia|Rep: Neural cell adhesion molecule L1 precursor - Homo sapiens (Human) Length = 1257 Score = 143 bits (347), Expect = 2e-32 Identities = 136/484 (28%), Positives = 202/484 (41%), Gaps = 37/484 (7%) Query: 10 EAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL----PAG 64 E P I EQ P + V +L C A G P RW + GV + P Sbjct: 33 EPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHS 92 Query: 65 GLFFLRATHGR-VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123 G F + + G+Y C A+N GTA S L + + + + +G+ Sbjct: 93 GSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGE 152 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIA 182 +VVL C PP + +YW N + L D R+ + GNL + +D Y C A Sbjct: 153 SVVLPCNPPPSAEPLRIYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA 211 Query: 183 RNAAGTR-----ESAIATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDP 229 + GTR E +K I KP L+ +VA G + +C G P Sbjct: 212 -HFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 270 Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288 P + W R +G MP RV + +L+L V D+GEY C AENS+G+ + Y+T Sbjct: 271 TPTIKWLRPSGP--MPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVT 328 Query: 289 VYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348 V P P S G AR C GRP+P + W + G I +++D+ + Sbjct: 329 VEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--R 383 Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408 + G +L ++ +D+ T C A N G + V P I+T Sbjct: 384 IQRGALIL--SNVQPSDTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYM 437 Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467 S A C A P P + W E G ++Q+ R +GTL ++DL +D+G Y C Sbjct: 438 AVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFC 497 Query: 468 VASS 471 +A++ Sbjct: 498 LAAN 501 Score = 127 bits (306), Expect = 2e-27 Identities = 159/609 (26%), Positives = 239/609 (39%), Gaps = 71/609 (11%) Query: 21 VTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGG-LFFLRATHGRVHS 78 V V + L C S P I W +L + R + G L+F HS Sbjct: 146 VEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHS 205 Query: 79 DAGVYWCEA--TNSYGTARSRNATLHVAVL-----REEFRLEPESKQS----AQGDTVVL 127 D Y C A + + L V R+ L P + S QG +VL Sbjct: 206 D---YICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVL 262 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 EC+ G P P + W + + D + L + + D G Y+C+A N+ G Sbjct: 263 ECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLG 319 Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSAGGGNMPL 246 + A + + PY + P+ + G + C+V G P P+V WR + Sbjct: 320 SARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK 378 Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306 + + G+L L NV +D CEA N G + A+ Y+ V P+ L+ ++ + Sbjct: 379 DQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMA 438 Query: 307 --GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 G+ A C A G P P++ W E T++ +++ A +G L I D N Sbjct: 439 VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LGIRDLQAN 490 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424 D+ C A N + + L V IT GP + S F C A Sbjct: 491 DT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTFTCQASFD 544 Query: 425 P--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480 P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+ Sbjct: 545 PSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRA 604 Query: 481 ALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKIGSSSILG 537 LLV V S PGP + + H +T + V +SWS ++ I Sbjct: 605 QLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED-HNAPIEK 647 Query: 538 YQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596 Y +E +E P W + + +QT +K L P + Y F V N +G Sbjct: 648 YDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPG 698 Query: 597 GPSPVSDSV 605 PSPVS++V Sbjct: 699 EPSPVSETV 707 Score = 116 bits (278), Expect = 5e-24 Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62 YVT APY + +P + A L+C+ G P P + W G+ V ++ + + Sbjct: 326 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 385 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121 G L SD V CEA N +G + NA ++V L + + ++ + Q Sbjct: 386 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 440 Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180 G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C Sbjct: 441 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 497 Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238 +A N + +A LK+ + GP + + GS VTF C+ DP P + W R Sbjct: 498 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 555 Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293 G LG ++DG L + ++ +D+G YSC A + V + L V P Sbjct: 556 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 612 Score = 40.7 bits (91), Expect = 0.24 Identities = 33/135 (24%), Positives = 57/135 (42%), Gaps = 6/135 (4%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753 +++ + YE + + +G + + +D P P + ILN++ V +KW Sbjct: 775 VSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWR 834 Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH-----QATSLIMTNLTSGVSYSV 808 P +L G + GYNV W + K H TS+I++ L SY + Sbjct: 835 PVDLAQVKGHLRGYNVTY-WREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHL 893 Query: 809 QIAAETIIGLGPFSQ 823 ++ A G GP S+ Sbjct: 894 EVQAFNGRGSGPASE 908 >UniRef50_UPI0000E815E6 Cluster: PREDICTED: similar to roundabout-like protein 4; n=2; Gallus gallus|Rep: PREDICTED: similar to roundabout-like protein 4 - Gallus gallus Length = 992 Score = 143 bits (346), Expect = 3e-32 Identities = 77/190 (40%), Positives = 106/190 (55%), Gaps = 4/190 (2%) Query: 100 TLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL 159 T A LR+ FRL+P G + L+C+PP G PEP V W+K+G L G H Sbjct: 35 TQRPAELRDNFRLQPGDLVVMAGQALELDCVPPAGQPEPRVTWRKDGVALRLAGGR--HQ 92 Query: 160 VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSV 219 + G L + AR++DAG Y C+A NAAG R S A + I KP ++ P DV A GS+V Sbjct: 93 LTRGKLWVASARRSDAGVYVCVAANAAGERHSRGAHVTILEKPVIVRRPSDVTAVAGSTV 152 Query: 220 TFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279 C GDP P V W + + G++P GR +V + +LRL V AD G Y C A++ +G Sbjct: 153 ELSCGAQGDPAPRVQWHKES--GDLPWGRHEVDQEHTLRLYAVTAADGGAYVCTAQSQLG 210 Query: 280 AVSASGYLTV 289 + +A+ L V Sbjct: 211 STAATARLRV 220 Score = 73.7 bits (173), Expect = 3e-11 Identities = 61/193 (31%), Positives = 81/193 (41%), Gaps = 15/193 (7%) Query: 17 QPLDVTVARHQPATLNC-RAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75 QP D+ V Q L+C G P P + W K GV + R L G L+ A Sbjct: 48 QPGDLVVMAGQALELDCVPPAGQPEPRVTWRKDGVALRLAGGRHQLTRGKLWVASARR-- 105 Query: 76 VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRG 134 SDAGVY C A N+ G SR A HV +L + + P + G TV L C +G Sbjct: 106 --SDAGVYVCVAANAAGERHSRGA--HVTILEKPVIVRRPSDVTAVAGSTVELSC-GAQG 160 Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194 P P V W K L + R + L + D G Y C A++ G S A Sbjct: 161 DPAPRVQWHKESGDLPW---GRHEVDQEHTLRLYAVTAADGGAYVCTAQSQLG---STAA 214 Query: 195 TLKIHIKPYLITG 207 T ++ ++ L G Sbjct: 215 TARLRVEGQLPAG 227 Score = 62.1 bits (144), Expect = 9e-08 Identities = 40/147 (27%), Positives = 63/147 (42%), Gaps = 3/147 (2%) Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC-RVGGDPLPDVLWRRSAGGGN 243 + G ES ++ P D+V G ++ C G P P V WR+ Sbjct: 26 SGGDMESPTTQRPAELRDNFRLQPGDLVVMAGQALELDCVPPAGQPEPRVTWRKDGVALR 85 Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASG-YLTVYDPPSINLSPNSV 302 + GR + L G L + + +D G Y C A N+ G + G ++T+ + P I P+ V Sbjct: 86 LAGGRHQ-LTRGKLWVASARRSDAGVYVCVAANAAGERHSRGAHVTILEKPVIVRRPSDV 144 Query: 303 NVESGNVARFTCTATGRPEPTMFWSVE 329 +G+ +C A G P P + W E Sbjct: 145 TAVAGSTVELSCGAQGDPAPRVQWHKE 171 Score = 53.6 bits (123), Expect = 3e-05 Identities = 50/196 (25%), Positives = 75/196 (38%), Gaps = 16/196 (8%) Query: 294 SINLSPNSVNVESGNVARFTCTA-TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352 + L P + V +G C G+PEP + W +G + G ++ T Sbjct: 44 NFRLQPGDLVVMAGQALELDCVPPAGQPEPRVTWRKDGVALRLAGG----RHQLTR---- 95 Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412 L + ++D+ VC A N AG RG + P+I PS+ T Sbjct: 96 -GKLWVASARRSDA-GVYVCVAANAAGERHSRGAHVTILEK----PVIVRRPSDVTAVAG 149 Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472 S C A P P + W+ E L R V + TL L + +D G Y C A S+ Sbjct: 150 STVELSCGAQGDPAPRVQWHKESGDLPWG-RHEVDQEHTLRLYAVTAADGGAYVCTAQSQ 208 Query: 473 HGKYVWSGALLVDSPI 488 G + L V+ + Sbjct: 209 LGSTAATARLRVEGQL 224 Score = 49.6 bits (113), Expect = 5e-04 Identities = 54/198 (27%), Positives = 85/198 (42%), Gaps = 14/198 (7%) Query: 627 RNNILTDHIVELIEATPIDSK-TIKLMWEILNFYYL-EGLFIYFRPLDNITIEYEMKTIL 684 R N+L + +L T + + T+ L W +L EG + +R L + + + + Sbjct: 233 RRNLLAVQL-QLDNGTALPTNATVWLRWRMLTPGPAPEGYVVLYRCLLPASTAWSQQDV- 290 Query: 685 HSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPP--INIEMFI 742 ++S I +L++ +YEF + P+ +G SNS ++VP P + + Sbjct: 291 -GRELSTI-IPALKRGYQYEFKVRPYAGGTQGLDSNSWHLWIPEEVPSAAPQRVTVGQAA 348 Query: 743 LNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTS 802 TV + W PP NGII GY V W + N TV T + T L Sbjct: 349 PGNGTVIVSWEPPPPDAHNGIIRGYQV---W--SLGEGWLQPTNHTVDGGTRRLETLLHG 403 Query: 803 -GVSYSVQIAAETIIGLG 819 G Y +Q+AA GLG Sbjct: 404 PGARYCIQVAAFNGAGLG 421 Score = 41.9 bits (94), Expect = 0.10 Identities = 17/43 (39%), Positives = 25/43 (58%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK 47 +VT E P I+ +P DVT L+C A G P+P ++W+K Sbjct: 128 HVTILEKPVIVRRPSDVTAVAGSTVELSCGAQGDPAPRVQWHK 170 Score = 38.3 bits (85), Expect = 1.3 Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 6/106 (5%) Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA--L 482 PEP + W +G AL R+ G L + +SD+G Y CVA++ G+ GA Sbjct: 71 PEPRVTWRKDGVALRLAGGRHQLTRGKLWVASARRSDAGVYVCVAANAAGERHSRGAHVT 130 Query: 483 LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNN 528 +++ P+ R +DV+++ G + D + + W + + Sbjct: 131 ILEKPVIVR----RPSDVTAVAGSTVELSCGAQGDPAPRVQWHKES 172 >UniRef50_P98160 Cluster: Basement membrane-specific heparan sulfate proteoglycan core protein precursor; n=26; Eumetazoa|Rep: Basement membrane-specific heparan sulfate proteoglycan core protein precursor - Homo sapiens (Human) Length = 4391 Score = 143 bits (346), Expect = 3e-32 Identities = 151/515 (29%), Positives = 212/515 (41%), Gaps = 61/515 (11%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 AP + + ++TV ATL C A GSP+P I W K + HR L L R Sbjct: 3211 APQVQAEEAELTVEAGHTATLRCSATGSPAPTIHWSKLRSPLPWQ-HR--LEGDTLIIPR 3267 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130 D+G Y C AT+ G A + LHV + PE G+TV L+CL Sbjct: 3268 VAQ----QDSGQYICNATSPAGHAEA-TIILHVESPPYATTV-PEHASVQAGETVQLQCL 3321 Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190 G+P W + G +L +R L L + A D+GRY+C N G+ E Sbjct: 3322 A-HGTPPLTFQWSRVGSSLPGRATARNEL-----LHFERAAPEDSGRYRCRVTNKVGSAE 3375 Query: 191 SAIATLKIHIKPYLITG--------------PEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 A A L + P + P+ G+SV F C V D + W Sbjct: 3376 -AFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWF 3434 Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS-- 294 + GG +P G + DG LR+ N+ + +G Y C+A G AS L + PS Sbjct: 3435 KE--GGQLPPGHS--VQDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVL 3490 Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354 IN+ + V G+ F C A G P+P + WS G + PG+ + V Sbjct: 3491 INIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGH--LRPGIVQSG-------GVVR 3541 Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414 + + D R C+A N AG++ L V + P I + P +P S Sbjct: 3542 IAHVELADAGQYR----CTATNAAGTTQSHVLLLVQA----LPQI--SMPQEVRVPAGSA 3591 Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 AVFPC A P P I+W +L + R + L+L + D+GTY C A++R G Sbjct: 3592 AVFPCIASGYPTPDISWSKLDGSLPPDSR---LENNMLMLPSVRPQDAGTYVCTATNRQG 3648 Query: 475 KYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTK 509 K L V + P +F S LP P K Sbjct: 3649 KVKAFAHLQVPERVVP---YFTQTPYSFLPLPTIK 3680 Score = 130 bits (313), Expect = 3e-28 Identities = 125/488 (25%), Positives = 192/488 (39%), Gaps = 35/488 (7%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSP-AIRWYKGGVLVVSDTHRSILPAGGLFFL 69 +P I P TV + Q A+ C +P ++ W + + H I P G + + Sbjct: 3021 SPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNVH--ISPNGSIITI 3078 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQ-GDTVVL 127 T H G Y C A+N+YG A+S N ++H + PE + G V L Sbjct: 3079 VGTRPSNH---GTYRCVASNAYGVAQSVVNLSVHGP---PTVSVLPEGPVWVKVGKAVTL 3132 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAA 186 EC+ G P + W + T L+D L I A+ +DAG Y C+A+NA Sbjct: 3133 ECVSA-GEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNAL 3191 Query: 187 GTRESAIATL-----KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241 GT + + + P + ++ + G + T +C G P P + W + Sbjct: 3192 GTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHWSKLRS- 3250 Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301 PL L+ +L + V D G+Y C A + G A+ L V PP P Sbjct: 3251 ---PLPWQHRLEGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVESPPYATTVPEH 3307 Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361 +V++G + C A G P T WS G+ PG + + + F+ D+ Sbjct: 3308 ASVQAGETVQLQCLAHGTPPLTFQWSRVGSS---LPGRATAR-NELLHFERAAP---EDS 3360 Query: 362 DKNDSRNTIVCSAVNYAGSSFVR---GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418 + R T + V+ G L TS P + P +T I + F Sbjct: 3361 GRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFH 3420 Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVW 478 C + W+ EG L H DG L +++LD+S GTY C A GK Sbjct: 3421 CAVPSDRGTQLRWFKEGGQLPPGHS---VQDGVLRIQNLDQSCQGTYICQAHGPWGKAQA 3477 Query: 479 SGALLVDS 486 S L++ + Sbjct: 3478 SAQLVIQA 3485 Score = 118 bits (283), Expect = 1e-24 Identities = 119/479 (24%), Positives = 182/479 (37%), Gaps = 38/479 (7%) Query: 8 SGEAPYIIE-QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66 + +AP ++E P V + +L C+ GSP W + V + L Sbjct: 1672 TNQAPLVVEVHPARSIVPQGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGSEL 1731 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GD 123 F SDAGVY C N + + SR L + + E ++S G Sbjct: 1732 HFPSVQP----SDAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGA 1787 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIA 182 V C SP + W T L +G +D G L I++ + +DAG Y C Sbjct: 1788 DVTFICTAKSKSPAYTLVW-----TRLHNGKLPTRAMDFNGILTIRNVQLSDAGTYVCTG 1842 Query: 183 RNAAGTRESAIATLKIHIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 N + ATL + P + P + Q G F+C G P P + W Sbjct: 1843 SNMF-AMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW-T 1900 Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY--DPPSI 295 GG +P + ++ G LRL V D+ +Y C A +S G A L V+ P + Sbjct: 1901 GGPGGQLP-AKAQI-HGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRV 1958 Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355 +SP V +G R C A G P T+ W EG P +R + A + + Sbjct: 1959 QVSPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGS---LPPQARSERTDIAT---LLI 2012 Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415 I D +C A + AG++ R ++ V S D PP + S+ ++ Sbjct: 2013 PAITTAD----AGFYLCVATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTL 2068 Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 C + + WY G +L + + + L L + +DSG Y C + G Sbjct: 2069 DLNCVVAGSAHAQVTWYRRGGSLPPHTQ---VHGSRLRLPQVSPADSGEYVCRVENGSG 2124 Score = 108 bits (260), Expect = 8e-22 Identities = 130/482 (26%), Positives = 184/482 (38%), Gaps = 52/482 (10%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 AP + P +TV Q A C A GSP+P + W GG I GG+ L Sbjct: 1865 APVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW-TGGPGGQLPAKAQI--HGGILRLP 1921 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHV-AVLREEFRLEPESKQSAQGDTVVLEC 129 A +D Y C A +S G +R A LHV ++ PE Q G TV L C Sbjct: 1922 AVE---PTDQAQYLCRAHSSAGQQVAR-AVLHVHGGGGPRVQVSPERTQVHAGRTVRLYC 1977 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189 G P + W+K G +L +R D L+I DAG Y C+A + AGT Sbjct: 1978 -RAAGVPSATITWRKEGGSL--PPQARSERTDIATLLIPAITTADAGFYLCVATSPAGTA 2034 Query: 190 ESAIATLKIHIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 ++ I + + P I V + G ++ C V G V W R GG++ Sbjct: 2035 QARIQVVVLSASDASPPPVKIESSSPSVTE-GQTLDLNCVVAGSAHAQVTWYRR--GGSL 2091 Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV----YDPPS------ 294 P +V LRL V AD GEY C EN G AS ++V + PS Sbjct: 2092 P-PHTQV-HGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPG 2149 Query: 295 ----INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350 I + P+S +V G C G+ + W G P +R + H Sbjct: 2150 STRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGS---LP--ARHQTHG---- 2200 Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV-TSDDDRPPPIITNGPSNQTL 409 ++L ++ DS VC V +G +T+ S P P + S+ T+ Sbjct: 2201 ---SLLRLHQVTPADS-GEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTV 2256 Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469 C + WY G +L H+ L + +D+G Y C A Sbjct: 2257 AEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQ---VRGSRLYIFQASPADAGQYVCRA 2313 Query: 470 SS 471 S+ Sbjct: 2314 SN 2315 Score = 103 bits (246), Expect = 4e-20 Identities = 125/496 (25%), Positives = 194/496 (39%), Gaps = 64/496 (12%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 V G P + + TVA Q L+C G + WYK G + + R + Sbjct: 2239 VIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPA---RHQVRGSR 2295 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNAT-------LHVAVLREEFRLEPESKQ 118 L+ +A+ +DAG Y C A+N + + T + A + R+EP S Q Sbjct: 2296 LYIFQASP----ADAGQYVCRASNGMEASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQ 2351 Query: 119 SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY 178 A+G T+ L C+ P G V W K G +L H G L + A D+G Y Sbjct: 2352 VAEGQTLDLNCVVP-GQSHAQVTWHKRGGSL-----PVRHQTHGSLLRLYQASPADSGEY 2405 Query: 179 QC-IARNAAGTRESAIATLK-------IHIKPYL-ITGPEDVVAQTGSSVTFQCRVGGDP 229 C + ++ S + T++ + + P + I VA+ G ++ C V G Sbjct: 2406 VCRVLGSSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAE-GQTLDLNCLVAGQA 2464 Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 V W + GG++P R +V LRL V AD GEY C S G AS +T+ Sbjct: 2465 HAQVTWHKR--GGSLP-ARHQV-HGSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTI 2520 Query: 290 YDPPS----------INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG----NRTII 335 S + + +S ++ +G+ C + T+ W G +R I Sbjct: 2521 QQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPSRHQI 2580 Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395 R T G V + ++ SR T + + +GSS V + Sbjct: 2581 VGSRLRIP-QVTPADSGEYVCHV--SNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESS 2637 Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLK 455 P ++ QTL + C P+ II WY G +L H+ T+ L L Sbjct: 2638 SPTVV----EGQTLDLN------CVVARQPQAIITWYKRGGSLPSRHQ---THGSHLRLH 2684 Query: 456 DLDKSDSGTYTCVASS 471 + +DSG Y C A++ Sbjct: 2685 QMSVADSGEYVCRANN 2700 Score = 96.3 bits (229), Expect = 4e-18 Identities = 126/512 (24%), Positives = 193/512 (37%), Gaps = 60/512 (11%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68 G P + + VA Q LNC G + W+K G + + R + L Sbjct: 2434 GVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPA---RHQVHGSRLRL 2490 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARS--------RNATLHVAVLREEFRLEPESKQSA 120 L+ T +D+G Y C S GT + R + H + R+E S A Sbjct: 2491 LQVTP----ADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLA 2546 Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180 G T+ L CL +P + W K G +L SR H + G L I D+G Y C Sbjct: 2547 NGHTLDLNCLVASQAPH-TITWYKRGGSL----PSR-HQIVGSRLRIPQVTPADSGEYVC 2600 Query: 181 IARNAAGTRE-SAIATLK----IHI----KPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231 N AG+RE S I T++ H+ P I V + G ++ C V P Sbjct: 2601 HVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVE-GQTLDLNCVVARQPQA 2659 Query: 232 DVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV-- 289 + W + GG++P R + LRL + +AD GEY C A N++ A+ AS ++V Sbjct: 2660 IITWYKR--GGSLP-SRHQT-HGSHLRLHQMSVADSGEYVCRANNNIDALEASIVISVSP 2715 Query: 290 -YDPPS-------INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF---PG 338 PS I + +S +V G C G+ + W G G Sbjct: 2716 SAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQTRG 2775 Query: 339 MSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398 +H + G V + + + +V + +GSS V + R P Sbjct: 2776 SRLRLHHVSPADSGEYVCRVMGSSGPLEASVLV--TIEASGSSAVHVPAPGGAPPIRIEP 2833 Query: 399 IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLD 458 + QTL +K C + W+ G L H+ + L L + Sbjct: 2834 SSSRVAEGQTLDLK------CVVPGQAHAQVTWHKRGGNLPARHQ---VHGPLLRLNQVS 2884 Query: 459 KSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490 +DSG Y+C + G + + L+ P +P Sbjct: 2885 PADSGEYSCQVTGSSGT-LEASVLVTIEPSSP 2915 Score = 94.3 bits (224), Expect = 2e-17 Identities = 134/512 (26%), Positives = 193/512 (37%), Gaps = 79/512 (15%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS--DTHRSILP 62 +V S P IE TV Q LNC P I WYK G + S TH S L Sbjct: 2624 HVPSVSPPIRIESS-SPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPSRHQTHGSHL- 2681 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE---------FRLE 113 H +D+G Y C A N+ A + + V+ R+E Sbjct: 2682 --------RLHQMSVADSGEYVCRANNNID-ALEASIVISVSPSAGSPSAPGSSMPIRIE 2732 Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT 173 S A+G+T+ L C+ P G V W K G +L H G L + Sbjct: 2733 SSSSHVAEGETLDLNCVVP-GQAHAQVTWHKRGGSL-----PSHHQTRGSRLRLHHVSPA 2786 Query: 174 DAGRYQCIARNAAGTRE-SAIATLK------IHIK-----PYLITGPEDVVAQTGSSVTF 221 D+G Y C ++G E S + T++ +H+ P + P G ++ Sbjct: 2787 DSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDL 2846 Query: 222 QCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281 +C V G V W + GGN+P R +V LRL+ V AD GEYSC+ S G + Sbjct: 2847 KCVVPGQAHAQVTWHKR--GGNLP-ARHQV-HGPLLRLNQVSPADSGEYSCQVTGSSGTL 2902 Query: 282 SASGYLTVYDPPS------------INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVE 329 AS +T+ +P S I + +S +V G C G+ + W Sbjct: 2903 EASVLVTI-EPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKR 2961 Query: 330 GNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389 G P +R + H + L ++ DS VC A + G TV Sbjct: 2962 GGS---LP--ARHQTHGSQ-------LRLHLVSPADS-GEYVCRAASGPGPE-QEASFTV 3007 Query: 390 T------SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGEALIQNH 442 T S P+I+ P + T+ A F C PI + W + L N Sbjct: 3008 TVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNV 3067 Query: 443 RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 + N + + S+ GTY CVAS+ +G Sbjct: 3068 HIS-PNGSIITIVGTRPSNHGTYRCVASNAYG 3098 Score = 93.9 bits (223), Expect = 2e-17 Identities = 82/286 (28%), Positives = 120/286 (41%), Gaps = 23/286 (8%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAG 64 + +G P + P T + +C +RW+K GG L + + Sbjct: 3394 IPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSVQD----- 3448 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124 G+ ++ S G Y C+A +G A++ + A+ + + G Sbjct: 3449 GVLRIQNLD---QSCQGTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHA 3505 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIAR 183 V ECL G P+P V W K G G R +V G +V I DAG+Y+C A Sbjct: 3506 VEFECLA-LGDPKPQVTWSKVG------GHLRPGIVQSGGVVRIAHVELADAGQYRCTAT 3558 Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 NAAGT +S + L + P I+ P++V GS+ F C G P PD+ W + G Sbjct: 3559 NAAGTTQSHVLLL-VQALPQ-ISMPQEVRVPAGSAAVFPCIASGYPTPDISWSK-LDGSL 3615 Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 P R L++ L L +V D G Y C A N G V A +L V Sbjct: 3616 PPDSR---LENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQV 3658 Score = 93.1 bits (221), Expect = 4e-17 Identities = 93/353 (26%), Positives = 137/353 (38%), Gaps = 46/353 (13%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64 +V G P + P V + L CRA G PS I W K G + Sbjct: 1949 HVHGGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARSERTDIA 2008 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE------FRLEPESKQ 118 L T +DAG Y C AT+ GTA++R + V VL ++E S Sbjct: 2009 TLLIPAIT----TADAGFYLCVATSPAGTAQAR---IQVVVLSASDASPPPVKIESSSPS 2061 Query: 119 SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY 178 +G T+ L C+ GS V W + G +L +++H G L + D+G Y Sbjct: 2062 VTEGQTLDLNCV-VAGSAHAQVTWYRRGGSL--PPHTQVH---GSRLRLPQVSPADSGEY 2115 Query: 179 QCIARNAAGTRESAIATLKIH--------------IKPYLITGPEDVVAQTGSSVTFQCR 224 C N +G +E++I +H +P I VA+ G ++ C Sbjct: 2116 VCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAE-GQTLDLNCV 2174 Query: 225 VGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSA 283 V G V W + GG++P + GS LRL V AD GEY C + G + A Sbjct: 2175 VPGQAHAQVTWHKR--GGSLP---ARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEA 2229 Query: 284 SGYLTVYDP------PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330 S +T+ P + + +S V G +C G+ + W G Sbjct: 2230 SVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRG 2282 Score = 82.6 bits (195), Expect = 6e-14 Identities = 117/500 (23%), Positives = 180/500 (36%), Gaps = 69/500 (13%) Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82 VA + LNC G + W+K G + S H++ G L H +D+G Sbjct: 2738 VAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSH-HQT---RGSRLRL---HHVSPADSGE 2790 Query: 83 YWCEATNSYGTAR---------SRNATLHVAVL--REEFRLEPESKQSAQGDTVVLECLP 131 Y C S G S ++ +HV R+EP S + A+G T+ L+C+ Sbjct: 2791 YVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVV 2850 Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191 P G V W K G L H V G L + D+G Y C ++GT E+ Sbjct: 2851 P-GQAHAQVTWHKRGGNL-----PARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEA 2904 Query: 192 AIATLKIHIKPYLITGP---EDVVAQTGSS-------VTFQCRVGGDPLPDVLWRRSAGG 241 ++ P I P + + + SS + C V G V W + G Sbjct: 2905 SVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKR--G 2962 Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP--------- 292 G++P LRL V AD GEY C A + G + + P Sbjct: 2963 GSLPARHQT--HGSQLRLHLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLR 3020 Query: 293 -PSINLSPNSVNVESGNVARFTCTATGRPEP-TMFWSVEGNRTIIFPGMSRDKYHATAVF 350 P I++ P S V+ G A F C P ++ W D H + Sbjct: 3021 SPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQEL-------EDNVH---IS 3070 Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT-L 409 +++TI T + + T C A N G + L+V PP ++ P + Sbjct: 3071 PNGSIITIVGT-RPSNHGTYRCVASNAYGVAQSVVNLSV-----HGPPTVSVLPEGPVWV 3124 Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN---VTNDGTLVLKDLDKSDSGTYT 466 + C + P W + +R + + L + SD+GTY Sbjct: 3125 KVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYV 3184 Query: 467 CVASSRHGKYVWSGALLVDS 486 C+A + G ++VD+ Sbjct: 3185 CLAQNALGTAQKQVEVIVDT 3204 Score = 70.1 bits (164), Expect = 3e-10 Identities = 73/291 (25%), Positives = 115/291 (39%), Gaps = 21/291 (7%) Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267 P + G S + +C+V G P W R G +P G + L +V +D Sbjct: 1683 PARSIVPQGGSHSLRCQVSGSPPHYFYWSRE-DGRPVPSGTQQRHQGSELHFPSVQPSDA 1741 Query: 268 GEYSCEAENSVGAVSASGYLTVYDPPSINLS-----PNSVNVESGNVARFTCTATGR-PE 321 G Y C N + ++ L V + PS ++ S +V G F CTA + P Sbjct: 1742 GVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAKSKSPA 1801 Query: 322 PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381 T+ W+ N + P + D F+G +LTI + +D+ T VC+ N Sbjct: 1802 YTLVWTRLHNGKL--PTRAMD-------FNG--ILTIRNVQLSDA-GTYVCTGSNMFAMD 1849 Query: 382 FVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN 441 L V + P+++ P T+ +A F C+A +P P + W G Q Sbjct: 1850 QGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW--TGGPGGQL 1907 Query: 442 HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492 + + G L L ++ +D Y C A S G+ V L V P + Sbjct: 1908 PAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRV 1958 Score = 51.6 bits (118), Expect = 1e-04 Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 4/82 (4%) Query: 397 PPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TL 452 PP + P + V F C AI P PII W + + R VT++G TL Sbjct: 405 PPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTL 464 Query: 453 VLKDLDKSDSGTYTCVASSRHG 474 +++D+ +SD G YTC A + G Sbjct: 465 IIRDVKESDQGAYTCEAMNARG 486 Score = 48.4 bits (110), Expect = 0.001 Identities = 32/85 (37%), Positives = 47/85 (55%), Gaps = 7/85 (8%) Query: 202 PYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDD---GS 256 P ++T P E + A G +VTF C G P P + WR G++P RV V + G+ Sbjct: 406 PQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWR--LNWGHIPSHPRVTVTSEGGRGT 463 Query: 257 LRLDNVILADEGEYSCEAENSVGAV 281 L + +V +D+G Y+CEA N+ G V Sbjct: 464 LIIRDVKESDQGAYTCEAMNARGMV 488 Score = 42.7 bits (96), Expect = 0.059 Identities = 25/74 (33%), Positives = 38/74 (51%), Gaps = 2/74 (2%) Query: 115 ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQT 173 ES Q+++G TV C+ G P P + W+ N + + G G L+I+D +++ Sbjct: 414 ESIQASRGQTVTFTCVAI-GVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKES 472 Query: 174 DAGRYQCIARNAAG 187 D G Y C A NA G Sbjct: 473 DQGAYTCEAMNARG 486 Score = 39.5 bits (88), Expect = 0.55 Identities = 25/82 (30%), Positives = 36/82 (43%), Gaps = 2/82 (2%) Query: 12 PYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 P ++ P + + +R Q T C A G P+P I W + S ++ GG L Sbjct: 406 PQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLI 465 Query: 71 ATHGRVHSDAGVYWCEATNSYG 92 + SD G Y CEA N+ G Sbjct: 466 IRDVK-ESDQGAYTCEAMNARG 486 >UniRef50_UPI0000E46295 Cluster: PREDICTED: similar to Down syndrome cell adhesion molecule, partial; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Down syndrome cell adhesion molecule, partial - Strongylocentrotus purpuratus Length = 2430 Score = 142 bits (345), Expect = 4e-32 Identities = 191/825 (23%), Positives = 318/825 (38%), Gaps = 86/825 (10%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSD---THRSILPAGGLFFLRATHGR-VHSDAGVYWCE 86 L+C G+P+P + W + G+ + +D T ++ R V D G+Y CE Sbjct: 866 LSCTVAGNPTPDVTWLRDGLPIPTDPRYTFNDVINEDSDVISYLNISRLVSEDGGLYRCE 925 Query: 87 ATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146 AT+ G + + ++V + R R P+ + G V + C G P ++ W K Sbjct: 926 ATSELGAVQHEDR-INV-IGRPLVRPLPDVI-AIDGTDVSIHCHVV-GFPITSITWYKGL 981 Query: 147 QTLLFDGDSRMHLVDGGNLVIQDARQT-DAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205 TL R ++ G LVI D D G Y C+A NA G R ++ L + + P +I Sbjct: 982 TTL--PSSMRHNVFPNGTLVIADVTSYGDGGEYTCVASNARGDRSASDMDLIVKVPP-VI 1038 Query: 206 TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR----VKVLDDGSLRLDN 261 E + + G C V P + +R G +P G V SL + + Sbjct: 1039 QPIEPLTLRQGQRTQLMCIVTRGDYP-IHFRWLKDGETIPHGVGIEFVNGTFSSSLLIAD 1097 Query: 262 VILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPE 321 +G Y+CEA N AV+ + LT+ PP + P++ V + C A G+P Sbjct: 1098 ASTVHDGRYTCEASNLAAAVNYTTALTIQVPPRFVVEPHNTAVVLNHTVVIACMANGKPN 1157 Query: 322 PTMFWSVEGN--RTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379 P + W T F + D L I + D+ +C N G Sbjct: 1158 PDVQWKKAPGPITTTNFRDLPDDPRFEMQENGS---LVIREARVEDA-GYYLCHISNSVG 1213 Query: 380 SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL- 438 LTV P N T+ + C A I W Sbjct: 1214 MESKTATLTVFV-----PATFEQQQQNVTVELTESITLECIATGHQPLEIMWSKNDVPFN 1268 Query: 439 -IQNHRRNV--TNDGTLVLKDLD-----KSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490 + R ++ DG VL + + D+ TY C+A + HG D + Sbjct: 1269 RLTTARYDIETVTDGDSVLSSMTIFSAVRDDTATYICLAQNLHG---------ADEHV-- 1317 Query: 491 NIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSG 550 I + V P PPT N T V LSW Q + G+S + G+ +E + Sbjct: 1318 -IQLW----VQEKPEPPTDLHVVNKTSRGVLLSW-QPSFDGNSPVTGFTLEYKNASDAWQ 1371 Query: 551 NNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDD 610 P+ +I + Y +K L P TY + N+ G+S PS + + Sbjct: 1372 TGLPQEHVPADLIGYQ-----YSIKHLHPAYTYHVRIFAFNAIGISDPSK---EILFDTE 1423 Query: 611 SNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRP 670 W+ TG+ E+ L + + P + +++ N + P Sbjct: 1424 EEDAWQ-TGLPQ--EHVPADLIGYQYSIKHLHPAYTYHVRIF--AFNAIGISD------P 1472 Query: 671 LDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDV 730 I + E + + +N + +T+L+K+T+Y L + + G S + TL+DV Sbjct: 1473 SKEILFDTEEEVPVETNYIESRTLTNLKKFTRYTIQLRAYNRVNVGPWSPQQFVTTLEDV 1532 Query: 731 PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTT-- 788 P P ++ + +T++ + W+ P+ NGI+ GY V + + N+ N + Sbjct: 1533 PSEAPHDVSARSVGSTSIMVFWNAPDQVSLNGILQGYRVY--YRPIRENEGFFLSNISFS 1590 Query: 789 -------VHQATSLI--MTNLTSGVSYSVQIAAETIIGLGPFSQK 824 +++ T L + NL +YS+ + A T +G G S++ Sbjct: 1591 EDELDYQIYETTELFAELHNLQKFTNYSLSVVAHTRVGEGVRSEE 1635 Score = 134 bits (325), Expect = 1e-29 Identities = 107/376 (28%), Positives = 162/376 (43%), Gaps = 22/376 (5%) Query: 17 QPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75 +PL DV +++C G P +I WYKG + S ++ P G L T Sbjct: 948 RPLPDVIAIDGTDVSIHCHVVGFPITSITWYKGLTTLPSSMRHNVFPNGTLVIADVTS-- 1005 Query: 76 VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGS 135 + D G Y C A+N+ G + + L V V +EP + + QG L C+ RG Sbjct: 1006 -YGDGGEYTCVASNARGDRSASDMDLIVKVPPVIQPIEPLTLR--QGQRTQLMCIVTRGD 1062 Query: 136 PEPNVYWKKNGQTLLFD-GDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194 + W K+G+T+ G ++ +L+I DA GRY C A N A A Sbjct: 1063 YPIHFRWLKDGETIPHGVGIEFVNGTFSSSLLIADASTVHDGRYTCEASNLAAAVNYTTA 1122 Query: 195 TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG------GNMPLG- 247 L I + P + P + +V C G P PDV W+++ G ++P Sbjct: 1123 -LTIQVPPRFVVEPHNTAVVLNHTVVIACMANGKPNPDVQWKKAPGPITTTNFRDLPDDP 1181 Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESG 307 R ++ ++GSL + + D G Y C NSVG S + LTV+ P + +V VE Sbjct: 1182 RFEMQENGSLVIREARVEDAGYYLCHISNSVGMESKTATLTVFVPATFEQQQQNVTVELT 1241 Query: 308 NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL---TINDTDKN 364 C ATG + WS + F ++ +Y V DG +VL TI ++ Sbjct: 1242 ESITLECIATGHQPLEIMWS---KNDVPFNRLTTARYDIETVTDGDSVLSSMTIFSAVRD 1298 Query: 365 DSRNTIVCSAVNYAGS 380 D+ T +C A N G+ Sbjct: 1299 DTA-TYICLAQNLHGA 1313 Score = 132 bits (319), Expect = 6e-29 Identities = 129/492 (26%), Positives = 195/492 (39%), Gaps = 44/492 (8%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 AP +I+ D T+ + L C A G P P +W K GV V RS+ GG L Sbjct: 666 APELIQSKADFTLRGGETVELPCVASGYPLPTYQWTKDGVPVTPGDSRSL--RGGNLLLS 723 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE--PESKQSAQGDTVVLE 128 +AG Y CEA N G +T ++R+ + P+ + G Sbjct: 724 NVQ---LENAGRYDCEAVNDLGAV----STTRNVIVRDSIAVYFYPQKRSVDVGAFATFN 776 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188 C G P V W KN Q L DGD R+ + + G +V+ R+ D G YQC+A N+ T Sbjct: 777 C-SVSGYPIEQVTWYKNAQPL--DGDDRVTVYENGTMVVGGMRRDDRGMYQCVASNSWQT 833 Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248 +E+ + KP ++ + Q G ++ C V G+P PDV W R G +P Sbjct: 834 QEATMQLSLGAAKPIMLAHFTNQTLQPGPNLQLSCTVAGNPTPDVTWLRD--GLPIPTDP 891 Query: 249 VKVLDD---------GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299 +D L + ++ D G Y CEA + +GAV + V P + P Sbjct: 892 RYTFNDVINEDSDVISYLNISRLVSEDGGLYRCEATSELGAVQHEDRINVIGRPLVRPLP 951 Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359 + + ++ +V+ C G P ++ W +G T+ P R VF T++ + Sbjct: 952 DVIAIDGTDVS-IHCHVVGFPITSITW-YKGLTTL--PSSMRHN-----VFPNGTLVIAD 1002 Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419 T D C A N G + + PP+I TL C Sbjct: 1003 VTSYGDG-GEYTCVASNARGDRSASDMDLIV----KVPPVI-QPIEPLTLRQGQRTQLMC 1056 Query: 420 TAICTPEPI-IAWYFEGEAL---IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 PI W +GE + + N T +L++ D G YTC AS+ Sbjct: 1057 IVTRGDYPIHFRWLKDGETIPHGVGIEFVNGTFSSSLLIADASTVHDGRYTCEASNLAAA 1116 Query: 476 YVWSGALLVDSP 487 ++ AL + P Sbjct: 1117 VNYTTALTIQVP 1128 Score = 116 bits (279), Expect = 4e-24 Identities = 131/491 (26%), Positives = 193/491 (39%), Gaps = 74/491 (15%) Query: 6 VTSGEAPYIIEQPLDVTV-ARHQPATLNCRAGGSPSPAIRWYKG--GVLVVSDTHRSILP 62 V+ + P + P V A Q L C A G P+P +RW G V + H I Sbjct: 493 VSGNKGPQFYQVPPSVVAFATTQGGRLTCSAIGDPTPVVRWVMAADGSAVQNIEHSRIAD 552 Query: 63 AGGL-----FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK 117 G F + VH GVY C ATN G+ RS P+ + Sbjct: 553 GNGTLSFPPFSSKEIIPEVHD--GVYRCIATNRIGSIRS-----------------PDIR 593 Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR 177 +A DT C+ ++Y + G+ R ++ G L I+D R DAG+ Sbjct: 594 VNA--DTWTSVCI--------SIYPRLRGE-------GRFSVLPSGELHIRDVRDRDAGQ 636 Query: 178 YQCIARNAAGTRESAIATLKIHIKPYLITGPE------DVVAQTGSSVTFQCRVGGDPLP 231 Y+C RN +H+ + T PE D + G +V C G PLP Sbjct: 637 YRCTVRNRLTNNNKVSPPAVLHVAEPVNTAPELIQSKADFTLRGGETVELPCVASGYPLP 696 Query: 232 DVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291 W + G + G + L G+L L NV L + G Y CEA N +GAVS + + V D Sbjct: 697 TYQWTKD--GVPVTPGDSRSLRGGNLLLSNVQLENAGRYDCEAVNDLGAVSTTRNVIVRD 754 Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 ++ P +V+ G A F C+ +G P + W P D+ V++ Sbjct: 755 SIAVYFYPQKRSVDVGAFATFNCSVSGYPIEQVTWYKNAQ-----PLDGDDR---VTVYE 806 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411 T++ + D R C A N S+ + T+ PI+ +NQTL Sbjct: 807 NGTMVV--GGMRRDDRGMYQCVASN----SWQTQEATMQLSLGAAKPIMLAHFTNQTLQP 860 Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHR---RNVTNDGTLVLKDLDKS-----DSG 463 CT P P + W +G + + R +V N+ + V+ L+ S D G Sbjct: 861 GPNLQLSCTVAGNPTPDVTWLRDGLPIPTDPRYTFNDVINEDSDVISYLNISRLVSEDGG 920 Query: 464 TYTCVASSRHG 474 Y C A+S G Sbjct: 921 LYRCEATSELG 931 Score = 106 bits (255), Expect = 3e-21 Identities = 124/495 (25%), Positives = 201/495 (40%), Gaps = 43/495 (8%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 A Y Q V V AT NC G P + WYK + D ++ G + Sbjct: 757 AVYFYPQKRSVDVGAF--ATFNCSVSGYPIEQVTWYKNAQPLDGDDRVTVYENGTM---- 810 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV-LREEFRLEPESKQSAQ-GDTVVLE 128 G D G+Y C A+NS+ T + AT+ +++ + L + Q+ Q G + L Sbjct: 811 VVGGMRRDDRGMYQCVASNSWQT---QEATMQLSLGAAKPIMLAHFTNQTLQPGPNLQLS 867 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN------LVIQDARQTDAGRYQCIA 182 C G+P P+V W ++G + D + V + L I D G Y+C A Sbjct: 868 CTVA-GNPTPDVTWLRDGLPIPTDPRYTFNDVINEDSDVISYLNISRLVSEDGGLYRCEA 926 Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242 + G + + + +P L+ DV+A G+ V+ C V G P+ + W + G Sbjct: 927 TSELGAVQHE-DRINVIGRP-LVRPLPDVIAIDGTDVSIHCHVVGFPITSITWYK--GLT 982 Query: 243 NMPLG-RVKVLDDGSLRLDNVI-LADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300 +P R V +G+L + +V D GEY+C A N+ G SAS + P + Sbjct: 983 TLPSSMRHNVFPNGTLVIADVTSYGDGGEYTCVASNARGDRSASDMDLIVKVPPVIQPIE 1042 Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360 + + G + C T P F ++ TI G+ + + T F ++L + Sbjct: 1043 PLTLRQGQRTQLMCIVTRGDYPIHFRWLKDGETIPH-GVGIEFVNGT--FSS-SLLIADA 1098 Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420 + +D R T C A N A + LT+ + PP P N + + V C Sbjct: 1099 STVHDGRYT--CEASNLAAAVNYTTALTI-----QVPPRFVVEPHNTAVVLNHTVVIACM 1151 Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTND--------GTLVLKDLDKSDSGTYTCVASSR 472 A P P + W + + R++ +D G+LV+++ D+G Y C S+ Sbjct: 1152 ANGKPNPDVQWKKAPGPITTTNFRDLPDDPRFEMQENGSLVIREARVEDAGYYLCHISNS 1211 Query: 473 HGKYVWSGALLVDSP 487 G + L V P Sbjct: 1212 VGMESKTATLTVFVP 1226 Score = 61.7 bits (143), Expect = 1e-07 Identities = 37/122 (30%), Positives = 57/122 (46%), Gaps = 3/122 (2%) Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTVVLECLPPRGSPEPNV 140 +W +A+ G S + + R R+ S + V L+CLP G P V Sbjct: 1717 FWVKASTIAGQGESSRIATEIPMSRVPARIMSFSTTLMTPWKRGVTLDCLPV-GDPVLTV 1775 Query: 141 YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200 WKKN + D R+ +++ G+LVIQ + TDAG Y C A N G+ +S +++ Sbjct: 1776 EWKKNRLPNVLKPDGRIDILENGSLVIQSVQSTDAGNYTCRAINEYGSSDSITVRVQVLA 1835 Query: 201 KP 202 P Sbjct: 1836 PP 1837 Score = 57.2 bits (132), Expect = 3e-06 Identities = 50/199 (25%), Positives = 93/199 (46%), Gaps = 20/199 (10%) Query: 639 IEATPIDSKTIKLMWEILNFYYLEGLF----IYFRP--------LDNITI-EYEMKTILH 685 + A + S +I + W + L G+ +Y+RP L NI+ E E+ ++ Sbjct: 1540 VSARSVGSTSIMVFWNAPDQVSLNGILQGYRVYYRPIRENEGFFLSNISFSEDELDYQIY 1599 Query: 686 SNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNT 745 E+ +L+K+T Y ++ + EG S ++ +T DVP+ P +I+ + Sbjct: 1600 ETTELFAELHNLQKFTNYSLSVVAHTRVGEGVRSEEKIVRTEQDVPEA-PADIKAHAASP 1658 Query: 746 TTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT-SLIMTNLTSGV 804 T++ + W PP L L NGIIT Y++ + + + ++ V + T ++ +L + Sbjct: 1659 TSIMVSWLPP-LYL-NGIITHYHLNIQYRE---GENEVRQEKELDPTTYYYLVEDLQTDY 1713 Query: 805 SYSVQIAAETIIGLGPFSQ 823 Y + A TI G G S+ Sbjct: 1714 EYDFWVKASTIAGQGESSR 1732 Score = 56.0 bits (129), Expect = 6e-06 Identities = 53/203 (26%), Positives = 83/203 (40%), Gaps = 17/203 (8%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P + +P + V + + C A G P+P ++W K + + R LP F ++ Sbjct: 1129 PRFVVEPHNTAVVLNHTVVIACMANGKPNPDVQWKKAPGPITTTNFRD-LPDDPRFEMQE 1187 Query: 72 THGRV-----HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126 V DAG Y C +NS G S+ ATL V V F + ++ +++ Sbjct: 1188 NGSLVIREARVEDAGYYLCHISNSVG-MESKTATLTVFV-PATFEQQQQNVTVELTESIT 1245 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL---VDG----GNLVIQDARQTDAGRYQ 179 LEC+ G + W KN +R + DG ++ I A + D Y Sbjct: 1246 LECI-ATGHQPLEIMWSKNDVPFNRLTTARYDIETVTDGDSVLSSMTIFSAVRDDTATYI 1304 Query: 180 CIARNAAGTRESAIATLKIHIKP 202 C+A+N G E I L + KP Sbjct: 1305 CLAQNLHGADEHVI-QLWVQEKP 1326 Score = 48.8 bits (111), Expect = 9e-04 Identities = 32/102 (31%), Positives = 51/102 (50%), Gaps = 4/102 (3%) Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNM-PLGRVKVLDDGSLRLDNVILADEGEYSCEAENS 277 VT C GDP+ V W+++ + P GR+ +L++GSL + +V D G Y+C A N Sbjct: 1761 VTLDCLPVGDPVLTVEWKKNRLPNVLKPDGRIDILENGSLVIQSVQSTDAGNYTCRAINE 1820 Query: 278 VGAV-SASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATG 318 G+ S + + V PP N ++ S N + +TG Sbjct: 1821 YGSSDSITVRVQVLAPP--NPPQLTIGSTSNNAIKVNWRSTG 1860 >UniRef50_Q4RE92 Cluster: Chromosome undetermined SCAF15134, whole genome shotgun sequence; n=488; root|Rep: Chromosome undetermined SCAF15134, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 10495 Score = 142 bits (344), Expect = 5e-32 Identities = 133/473 (28%), Positives = 202/473 (42%), Gaps = 34/473 (7%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 DV+V + +P TL C G+P + WYK G V + +I L Sbjct: 9214 DVSVEKGKPLTLECTYTGTPKITVNWYKDGQQVFASYKYNITTTESSCILECLSTDDKEA 9273 Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVLECLPPRGSPEP 138 AG Y CE +N G A V++L + +E E + GD V L+C G+PE Sbjct: 9274 AGKYLCEVSNDAGRDTCEAA---VSILEPPYFVESLEPMEVTAGDAVCLKC-KVAGTPEI 9329 Query: 139 NVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197 V W K + R+ G L + A + D G Y C A N G S+ Sbjct: 9330 KVSWFKADGKVRSSPTCRLEYTKGVACLKLSKATKADIGEYSCKAENRIGATSSSCRLNV 9389 Query: 198 IHIKPYLITGPEDVVA--QT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL-D 253 + K T P+ + + QT G + F+CR+ G +V W R G G +L D Sbjct: 9390 LEAKTPP-TFPKKITSLQQTEGQPIRFECRIAGSSPIEVSWLRD-GEPLKAGGEFSMLYD 9447 Query: 254 DGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP--PSI---NLSPNSVNVES 306 D + L+++ + GEY+C A NSVG+ S LT+ +P P + L+P V + Sbjct: 9448 DNTAVLQIERGEMRHSGEYTCVATNSVGSTSCRAKLTLQEPRYPPVFDRKLAPQEVTM-- 9505 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 G+ C TG + WS + ++ I S Y+ + V D LTI DK D+ Sbjct: 9506 GDSIELECHMTGSAPIKVTWS-KDHKDI----RSGGNYNISCV-DNTPHLTILKADKGDT 9559 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426 C A+N G V VT + + PP+ T PS + V + + Sbjct: 9560 -GKYFCHAMNDVGK--VSCSSDVTVKERKNPPVFTKKPSEHMEDTEGRLVKIEGRVSGSQ 9616 Query: 427 PI-IAWYFEGEALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 P+ ++WY E + + + ++ +N L +K +DSG YTC AS+ G+ Sbjct: 9617 PMSVSWYKEDAEIHSSDKYDISFKSNVAVLCIKSSHVTDSGRYTCQASNEAGR 9669 Score = 133 bits (321), Expect = 3e-29 Identities = 121/462 (26%), Positives = 187/462 (40%), Gaps = 22/462 (4%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P I+E+P + V N G+P I+W+K ++S S++ L Sbjct: 8055 EPPCILEKPESMNVLPGSKVHFNVLLSGTPPLTIKWFKNQKEILSSADCSVIKDNTSTSL 8114 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 + SD+G Y CE N G+ S ATL V + R + G V EC Sbjct: 8115 ALFFAK-SSDSGEYRCEIQNDVGST-SCQATLFVKEPPKFTRTPARVSVTRLGQNKVFEC 8172 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGT 188 G+PE +VYW K G + +M ++ +L + D+G Y C ARN AG+ Sbjct: 8173 -QVTGTPEIDVYWFKEGSEIHPSERYQMSFLNSLASLEVCGTETKDSGLYYCEARNEAGS 8231 Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248 ES LK+ P +I S+ +C+V G +V W R A Sbjct: 8232 -ESCSMELKVKEIPTIIKDLAPAELVKDSTAHLECQVTGTSPFEVTWYRDAKEIKSSAKH 8290 Query: 249 VKVLDDGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306 +G+L L+ AD GEY C N VG+ ++ L + +PP+ + + Sbjct: 8291 SFSQINGTLGLEVHKCGAADVGEYQCTVANEVGSCTSKATLKLKEPPTFTKKLENTDTVL 8350 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 G +A F C G P ++ W + N + P + R + V +L I + S Sbjct: 8351 GKMAVFQCVVEGSPTLSVQWQKDDNWILEDPKIER------TFENNVAILKIPACEAVHS 8404 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426 C VN AG + LTV + PP IT P + + C +P Sbjct: 8405 -GKYSCQVVNEAGQTKCSATLTV-----QEPPQITEKPEVIKVTVGDPVSLDCKVTGSPA 8458 Query: 427 PIIAWYFEGEAL--IQNHRRNVTND-GTLVLKDLDKSDSGTY 465 + W EG+ L I+ H+ N+ +L ++ ++ D G Y Sbjct: 8459 LKVKWMKEGKELQSIRQHKLVFENNISSLKIQAAEREDEGEY 8500 Score = 132 bits (319), Expect = 6e-29 Identities = 124/490 (25%), Positives = 197/490 (40%), Gaps = 23/490 (4%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 +T E I ++ ++V + PATL R G+ W K G ++S +L Sbjct: 7862 LTVKEPAEITDEAKSISVTQGDPATLEARFSGTKPLRAMWIKAGKELISGQRYKVLSTDS 7921 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDT 124 L+ + SD G Y +N G + T+ ++ F + + + + Sbjct: 7922 SSVLK-INKTDKSDGGEYTFRVSNDVGQSSCEVTLTILDQIIPPSFTRKLKQTEGIKASF 7980 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIAR 183 LECL GS V+W K+ + + D + + L I D D G Y CIA+ Sbjct: 7981 AHLECL-VSGSLPITVHWYKDDKEIQADHKHKCTFFENVAFLEISDLDSKDGGSYTCIAK 8039 Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-- 241 N AG + + A L + P ++ PE + GS V F + G P + W ++ Sbjct: 8040 NKAGAVQCS-AILLVKEPPCILEKPESMNVLPGSKVHFNVLLSGTPPLTIKWFKNQKEIL 8098 Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301 + +K SL L +D GEY CE +N VG+ S L V +PP +P Sbjct: 8099 SSADCSVIKDNTSTSLALFFAKSSDSGEYRCEIQNDVGSTSCQATLFVKEPPKFTRTPAR 8158 Query: 302 VNV-ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360 V+V G F C TG PE ++W EG+ I P ++Y + + + L + Sbjct: 8159 VSVTRLGQNKVFECQVTGTPEIDVYWFKEGSE--IHPS---ERYQ-MSFLNSLASLEVCG 8212 Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420 T+ DS C A N AGS +L V + P I + L S A C Sbjct: 8213 TETKDS-GLYYCEARNEAGSESCSMELKV-----KEIPTIIKDLAPAELVKDSTAHLECQ 8266 Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTN-DGTLVLK--DLDKSDSGTYTCVASSRHGKYV 477 T + WY + + + + + + + +GTL L+ +D G Y C ++ G Sbjct: 8267 VTGTSPFEVTWYRDAKEIKSSAKHSFSQINGTLGLEVHKCGAADVGEYQCTVANEVGSCT 8326 Query: 478 WSGALLVDSP 487 L + P Sbjct: 8327 SKATLKLKEP 8336 Score = 131 bits (317), Expect = 1e-28 Identities = 125/531 (23%), Positives = 214/531 (40%), Gaps = 28/531 (5%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E I+++P ++V A L + G+P +W+K G+ + S I + + L Sbjct: 8921 EPAKIVDKPDALSVTAGDIAALEVKVCGTPELVTKWFKDGIELASGNKYKISFSRMISCL 8980 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLE 128 D+G Y E N G S+ N T+ ++ F + + + G +E Sbjct: 8981 NVLSTE-KLDSGEYTFEIMNEVGKDLSKINLTVLDKIIPPSFSRKLKDCHTVVGKAGEME 9039 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAG 187 C GSP + W +G+ + + + + ++ + + +D+G Y+C A N AG Sbjct: 9040 C-KVSGSPPFAISWHHDGEEIQSGPNYEISFSNNSCILRVPTLKLSDSGLYKCKAVNEAG 9098 Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247 T E+A AT+ + P + P+ + A GS+VTF V G + W R G M G Sbjct: 9099 TSETA-ATMDVKEPPSFVVPPQSLEALPGSNVTFSAMVKGSAPLKLKWFR--GAKEMEPG 9155 Query: 248 R-----VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302 R + + L L NV + GEY+C+ N G S L++ +P + + V Sbjct: 9156 RTCSFSLTSTNQVMLELFNVDRSHAGEYTCQIINDAGKESWPVNLSIKEPAAFSKKLKDV 9215 Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362 +VE G CT TG P+ T+ W +G + +F KY+ T + +L TD Sbjct: 9216 SVEKGKPLTLECTYTGTPKITVNWYKDGQQ--VFASY---KYNITTT-ESSCILECLSTD 9269 Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422 ++ +C N AG +++ PP + C Sbjct: 9270 DKEAAGKYLCEVSNDAGRDTCEAAVSILE-----PPYFVESLEPMEVTAGDAVCLKCKVA 9324 Query: 423 CTPEPIIAWYFEGEALIQNH---RRNVTND-GTLVLKDLDKSDSGTYTCVASSRHGKYVW 478 TPE ++W F+ + +++ R T L L K+D G Y+C A +R G Sbjct: 9325 GTPEIKVSW-FKADGKVRSSPTCRLEYTKGVACLKLSKATKADIGEYSCKAENRIGATSS 9383 Query: 479 SGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529 S L V P + + G P + + + +SW ++ + Sbjct: 9384 SCRLNVLEAKTPPTFPKKITSLQQTEGQPIRFECRIAGSSPIEVSWLRDGE 9434 Score = 124 bits (300), Expect = 1e-26 Identities = 133/511 (26%), Positives = 207/511 (40%), Gaps = 27/511 (5%) Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86 Q + L CRA GSP +W+K + + ++ + L + +++G Y C Sbjct: 7604 QSSRLECRATGSPVIIFKWFKDEMEITPGPKYTMAADDLVASLEIVQCTL-AESGDYVCV 7662 Query: 87 ATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146 A++ G+ R A F ESK +G ++LE GS V KNG Sbjct: 7663 ASSEAGSDCCRGTVTVKAP--PSFVRSLESKDVVKGSELMLEG-QVSGSAPFTVTLCKNG 7719 Query: 147 QTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205 + + D R+ + D L + D G YQC N G R S + + P + Sbjct: 7720 KAIRNDKRHRITVKDELIALQVLAVEAGDVGLYQCTVENQVG-RVSCDCHVTLKDPPSFV 7778 Query: 206 TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNV 262 E++ + GS V+ C + G V W + +++ + + L + +V Sbjct: 7779 QKLENLSSLVGSEVSLLCVLKGSEPMVVSWMKD-NHELKEAEHIQITYESNTALLHITDV 7837 Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEP 322 G+YSC+A+N G+ + S LTV +P I S++V G+ A +G Sbjct: 7838 QRNHAGKYSCQAQNQAGSQTCSALLTVKEPAEITDEAKSISVTQGDPATLEARFSGTKPL 7897 Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382 W G I S +Y + D +VL IN TDK+D N G S Sbjct: 7898 RAMWIKAGKELI-----SGQRYKVLST-DSSSVLKINKTDKSDG-GEYTFRVSNDVGQSS 7950 Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIK-SMAVFPCTAICTPEPIIAWYFEGEALIQN 441 ++T+T D PP T QT IK S A C + + WY + + + + Sbjct: 7951 C--EVTLTILDQIIPPSFTR-KLKQTEGIKASFAHLECLVSGSLPITVHWYKDDKEIQAD 8007 Query: 442 HRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAA 498 H+ T N L + DLD D G+YTC+A ++ G S LLV P P I + Sbjct: 8008 HKHKCTFFENVAFLEISDLDSKDGGSYTCIAKNKAGAVQCSAILLVKEP--PCI-LEKPE 8064 Query: 499 DVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529 ++ LPG +T+ W +N K Sbjct: 8065 SMNVLPGSKVHFNVLLSGTPPLTIKWFKNQK 8095 Score = 120 bits (290), Expect = 2e-25 Identities = 122/495 (24%), Positives = 193/495 (38%), Gaps = 27/495 (5%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P + P + T + GS ++W++G + S + Sbjct: 9110 EPPSFVVPPQSLEALPGSNVTFSAMVKGSAPLKLKWFRGAKEMEPGRTCSFSLTSTNQVM 9169 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 S AG Y C+ N G S L + F + + +G + LEC Sbjct: 9170 LELFNVDRSHAGEYTCQIINDAGK-ESWPVNLSIKE-PAAFSKKLKDVSVEKGKPLTLEC 9227 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTD----AGRYQCIARNA 185 G+P+ V W K+GQ + + ++ + I + TD AG+Y C N Sbjct: 9228 TYT-GTPKITVNWYKDGQQVF--ASYKYNITTTESSCILECLSTDDKEAAGKYLCEVSND 9284 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNM 244 AG R++ A + I PY + E + G +V +C+V G P V W ++ G + Sbjct: 9285 AG-RDTCEAAVSILEPPYFVESLEPMEVTAGDAVCLKCKVAGTPEIKVSWFKADGKVRSS 9343 Query: 245 PLGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLSPN 300 P R++ L+L AD GEYSC+AEN +GA S+S L V + PP+ Sbjct: 9344 PTCRLEYTKGVACLKLSKATKADIGEYSCKAENRIGATSSSCRLNVLEAKTPPTFPKKIT 9403 Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360 S+ G RF C G + W +G P + ++ + D VL I Sbjct: 9404 SLQQTEGQPIRFECRIAGSSPIEVSWLRDGE-----PLKAGGEF-SMLYDDNTAVLQIER 9457 Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420 + S C A N GS+ R KLT+ + R PP+ + Q + + C Sbjct: 9458 GEMRHS-GEYTCVATNSVGSTSCRAKLTL--QEPRYPPVFDRKLAPQEVTMGDSIELECH 9514 Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477 + + W + + + N++ N L + DK D+G Y C A + GK Sbjct: 9515 MTGSAPIKVTWSKDHKDIRSGGNYNISCVDNTPHLTILKADKGDTGKYFCHAMNDVGKVS 9574 Query: 478 WSGALLVDSPINPNI 492 S + V NP + Sbjct: 9575 CSSDVTVKERKNPPV 9589 Score = 113 bits (271), Expect = 4e-23 Identities = 119/510 (23%), Positives = 202/510 (39%), Gaps = 28/510 (5%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 + C+ GSP AI W+ G + S + I + LR ++ SD+G+Y C+A N Sbjct: 9038 MECKVSGSPPFAISWHHDGEEIQSGPNYEISFSNNSCILRVPTLKL-SDSGLYKCKAVNE 9096 Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150 GT+ + AT+ V F + P+S ++ G V + +GS + W + + + Sbjct: 9097 AGTSETA-ATMDVKE-PPSFVVPPQSLEALPGSNVTFSAMV-KGSAPLKLKWFRGAKEME 9153 Query: 151 FDGDSRMHLVDGGNLVIQ--DARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208 L ++++ + ++ AG Y C N AG +ES L I Sbjct: 9154 PGRTCSFSLTSTNQVMLELFNVDRSHAGEYTCQIINDAG-KESWPVNLSIKEPAAFSKKL 9212 Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE- 267 +DV + G +T +C G P V W + + S L+ + D+ Sbjct: 9213 KDVSVEKGKPLTLECTYTGTPKITVNWYKDGQQVFASYKYNITTTESSCILECLSTDDKE 9272 Query: 268 --GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325 G+Y CE N G + +++ +PP S + V +G+ C G PE + Sbjct: 9273 AAGKYLCEVSNDAGRDTCEAAVSILEPPYFVESLEPMEVTAGDAVCLKCKVAGTPEIKVS 9332 Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385 W + P R +Y GV L ++ K D C A N G++ Sbjct: 9333 WFKADGKVRSSP-TCRLEYTK-----GVACLKLSKATKADI-GEYSCKAENRIGATSSSC 9385 Query: 386 KLTVTSDDDRP--PPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGEALIQNH 442 +L V P P IT+ + PI+ F C I PI ++W +GE L Sbjct: 9386 RLNVLEAKTPPTFPKKITSLQQTEGQPIR----FECR-IAGSSPIEVSWLRDGEPLKAGG 9440 Query: 443 RRNVTNDGTLVLKDLDKSD---SGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAAD 499 ++ D + +++ + SG YTCVA++ G L + P P + + A Sbjct: 9441 EFSMLYDDNTAVLQIERGEMRHSGEYTCVATNSVGSTSCRAKLTLQEPRYPPVFDRKLAP 9500 Query: 500 VSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529 G + H + ++WS+++K Sbjct: 9501 QEVTMGDSIELECHMTGSAPIKVTWSKDHK 9530 Score = 109 bits (263), Expect = 3e-22 Identities = 122/491 (24%), Positives = 198/491 (40%), Gaps = 42/491 (8%) Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86 QP CR GS + W + G + + S+L L+ G + +G Y C Sbjct: 9411 QPIRFECRIAGSSPIEVSWLRDGEPLKAGGEFSMLYDDNTAVLQIERGEMRH-SGEYTCV 9469 Query: 87 ATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145 ATNS G+ R TL F + ++ GD++ LEC GS V W K+ Sbjct: 9470 ATNSVGSTSCRAKLTLQEPRYPPVFDRKLAPQEVTMGDSIELEC-HMTGSAPIKVTWSKD 9528 Query: 146 GQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRE-SAIATLKIHIKPY 203 + + G+ + VD +L I A + D G+Y C A N G S+ T+K P Sbjct: 9529 HKDIRSGGNYNISCVDNTPHLTILKADKGDTGKYFCHAMNDVGKVSCSSDVTVKERKNPP 9588 Query: 204 LITG-PEDVVAQT-GSSVTFQCRVGGDPLPDVLW-RRSAGGGNMPLGRVKVLDDGS-LRL 259 + T P + + T G V + RV G V W + A + + + + L + Sbjct: 9589 VFTKKPSEHMEDTEGRLVKIEGRVSGSQPMSVSWYKEDAEIHSSDKYDISFKSNVAVLCI 9648 Query: 260 DNVILADEGEYSCEAENSVGAVSAS---GYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316 + + D G Y+C+A N G S G PP ++ + V+ G C Sbjct: 9649 KSSHVTDSGRYTCQASNEAGRASCCTTVGISEAKKPPVFDVPLKPLTVDEGEKMSLKCHV 9708 Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376 G + W ++ + + G ++ + DG L I+ + D+ + + C A N Sbjct: 9709 CGSAPLIIQW-MKDRKELTSGGNTKISFT-----DGTACLEISPASRKDAGDYL-CKATN 9761 Query: 377 YAGSSFVRGKLTV-------TSDDDRP---PPI-------ITNGPSNQTLPIKSMAVFPC 419 AGS F + K+ V + + P P+ P + KS A F Sbjct: 9762 DAGSEFSKAKVAVRQKPGAALAPAEAPAVAAPVKRQDNLFFIEEPKAVRVTEKSTATFMT 9821 Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTND-----GTLVLKDLDKSDSGTYTCVASSRHG 474 P P + W +G+ H ++ D L ++++ +SDSG Y C+AS++HG Sbjct: 9822 KVGGDPIPSVKW-MKGKWRQMTHGGRISVDQKGQEAKLEIREVTRSDSGQYRCIASNKHG 9880 Query: 475 KYVWSGALLVD 485 + S LLV+ Sbjct: 9881 EIECSSDLLVE 9891 Score = 106 bits (255), Expect = 3e-21 Identities = 93/384 (24%), Positives = 145/384 (37%), Gaps = 16/384 (4%) Query: 10 EAPYIIEQPLDVTVAR-HQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68 E P P V+V R Q C+ G+P + W+K G + + L Sbjct: 8148 EPPKFTRTPARVSVTRLGQNKVFECQVTGTPEIDVYWFKEGSEIHPSERYQMSFLNSLAS 8207 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128 L G D+G+Y+CEA N G+ S + L V + + + + + T LE Sbjct: 8208 LEVC-GTETKDSGLYYCEARNEAGS-ESCSMELKVKEIPTIIK-DLAPAELVKDSTAHLE 8264 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAG 187 C SP V W ++ + + ++G L + D G YQC N G Sbjct: 8265 CQVTGTSPF-EVTWYRDAKEIKSSAKHSFSQINGTLGLEVHKCGAADVGEYQCTVANEVG 8323 Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMP 245 + S ATLK+ P E+ G FQC V G P V W++ + Sbjct: 8324 SCTSK-ATLKLKEPPTFTKKLENTDTVLGKMAVFQCVVEGSPTLSVQWQKDDNWILEDPK 8382 Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305 + R + L++ G+YSC+ N G S LTV +PP I P + V Sbjct: 8383 IERTFENNVAILKIPACEAVHSGKYSCQVVNEAGQTKCSATLTVQEPPQITEKPEVIKVT 8442 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365 G+ C TG P + W EG + + H + ++ L I ++ D Sbjct: 8443 VGDPVSLDCKVTGSPALKVKWMKEGKE------LQSIRQHKLVFENNISSLKIQAAERED 8496 Query: 366 SRNTIVCSAVNYAGSSFVRGKLTV 389 I+ N+ + + +L V Sbjct: 8497 EGEYIL-EVANHISRTSCKVRLVV 8519 Score = 105 bits (253), Expect = 6e-21 Identities = 123/489 (25%), Positives = 188/489 (38%), Gaps = 28/489 (5%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA-GGLFF 68 E P ++ VT L GS ++W K + D L + F Sbjct: 7210 EPPSFTKRVDSVTAVLGTTVKLQGTVKGSSPITVKWMKDSEYLRDDDPSITLTFDNNVAF 7269 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQ-GDTVV 126 L + S G Y C+A N G +S ATL V +E R+ EP + S G++ Sbjct: 7270 LSIATVAI-SHGGKYVCQAENEAGQQKSE-ATLTV---QEPARVVEPAASISVTAGESAT 7324 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNA 185 LE GSPE V W K+G+ + +M + D + I A ++D+ Y N Sbjct: 7325 LESTIS-GSPELKVKWFKDGKEMTSGRKCKMTVKDNTATMKILSAEKSDSAEYIMQVSNK 7383 Query: 186 AGTRESAIA-TLKIHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 G E + T+ P T P V A G+ + C+V G + W + Sbjct: 7384 VGKDECTCSLTVLDRTMPPTFTKPLRRVDANIGNDASLDCKVSGSQPMTIAWFKDDHEIT 7443 Query: 244 M-PLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301 P + D +L++ + AD G Y C A NS G SG L V +PP+ + P+ Sbjct: 7444 AGPKFQAGFKDHSATLQIAGLEKADSGVYKCRATNSAGFKETSGTLYVKEPPTFTVKPDG 7503 Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361 +V G+ F TG T+ W E ++ I+ G K AT+ + L + Sbjct: 7504 QDVIPGSTVSFRAAFTGTAPLTVKWFKE-DKEIVSGGTYFIKKDATS-----SSLELQAV 7557 Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421 +DS C N AG L V PP + + + + C A Sbjct: 7558 KPSDSAR-YACQVSNDAGKVDCTALLFV----KEPPTFVRKLEATTLVTCGQSSRLECRA 7612 Query: 422 ICTPEPIIAWYFEGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTCVASSRHGKYVW 478 +P I W+ + + + + D +L + ++SG Y CVASS G Sbjct: 7613 TGSPVIIFKWFKDEMEITPGPKYTMAADDLVASLEIVQCTLAESGDYVCVASSEAGSDCC 7672 Query: 479 SGALLVDSP 487 G + V +P Sbjct: 7673 RGTVTVKAP 7681 Score = 105 bits (251), Expect = 1e-20 Identities = 129/555 (23%), Positives = 212/555 (38%), Gaps = 46/555 (8%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P + P + + + +L C G+ + W+K ++ +L G L Sbjct: 8734 EPPSFTKVPEPMEGLKGKDVSLYCELAGTAPFQVTWFKDKKPLMESRKYKMLSEGSSVTL 8793 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVVL 127 G +D G Y C+ +NS G+ + + LRE F + + G V L Sbjct: 8794 HII-GLESTDIGQYECKVSNSVGSDTCQT----LVKLREPPSFVKKLSNMTVVLGQEVTL 8848 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ--DARQTDAGRYQCIARNA 185 + +GS V W ++ +L DGD+R + + ++ A + AGRY C N Sbjct: 8849 QATV-KGSEPITVSWVQDKDHILRDGDNRRITFENNTVTLKVFKADASTAGRYTCHLTND 8907 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGG 241 AGT E A L + ++ P+ + G + +V G P W + A G Sbjct: 8908 AGTSE-CFANLNVLEPAKIVDKPDALSVTAGDIAALEVKVCGTPELVTKWFKDGIELASG 8966 Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLS 298 + +++ L + + D GEY+ E N VG + LTV D PPS + Sbjct: 8967 NKYKISFSRMI--SCLNVLSTEKLDSGEYTFEIMNEVGKDLSKINLTVLDKIIPPSFSRK 9024 Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358 + G C +G P + W +G P + + + +L + Sbjct: 9025 LKDCHTVVGKAGEMECKVSGSPPFAISWHHDGEEIQSGPN------YEISFSNNSCILRV 9078 Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418 +DS C AVN AG+S + T D PP + S + LP ++ Sbjct: 9079 PTLKLSDS-GLYKCKAVNEAGTS----ETAATMDVKEPPSFVVPPQSLEALPGSNVTF-- 9131 Query: 419 CTAICTPEPIIAWYFEGEALIQNHRR-----NVTNDGTLVLKDLDKSDSGTYTCVASSRH 473 + P+ +F G ++ R TN L L ++D+S +G YTC + Sbjct: 9132 SAMVKGSAPLKLKWFRGAKEMEPGRTCSFSLTSTNQVMLELFNVDRSHAGEYTCQIINDA 9191 Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPP-TKPITHNVTDTSVTLSWSQNNKIGS 532 GK W L + P + DVS G P T T+ T +T++W K G Sbjct: 9192 GKESWPVNLSIKEPA---AFSKKLKDVSVEKGKPLTLECTYTGT-PKITVNW---YKDGQ 9244 Query: 533 SSILGYQVEVFSRET 547 Y+ + + E+ Sbjct: 9245 QVFASYKYNITTTES 9259 Score = 100 bits (239), Expect = 3e-19 Identities = 124/537 (23%), Positives = 208/537 (38%), Gaps = 30/537 (5%) Query: 2 SDDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL 61 S+ +T E ++E ++V + ATL GSP ++W+K G + S + Sbjct: 7296 SEATLTVQEPARVVEPAASISVTAGESATLESTISGSPELKVKWFKDGKEMTSGRKCKMT 7355 Query: 62 PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESKQSA 120 ++ SD+ Y + +N G + + T+ + F + Sbjct: 7356 VKDNTATMKILSAE-KSDSAEYIMQVSNKVGKDECTCSLTVLDRTMPPTFTKPLRRVDAN 7414 Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQ 179 G+ L+C GS + W K+ + + D L I + D+G Y+ Sbjct: 7415 IGNDASLDC-KVSGSQPMTIAWFKDDHEITAGPKFQAGFKDHSATLQIAGLEKADSGVYK 7473 Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW---- 235 C A N+AG +E++ TL + P P+ GS+V+F+ G V W Sbjct: 7474 CRATNSAGFKETS-GTLYVKEPPTFTVKPDGQDVIPGSTVSFRAAFTGTAPLTVKWFKED 7532 Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS- 294 + GG + K SL L V +D Y+C+ N G V + L V +PP+ Sbjct: 7533 KEIVSGGTYFI--KKDATSSSLELQAVKPSDSARYACQVSNDAGKVDCTALLFVKEPPTF 7590 Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354 + + V G +R C ATG P W + I PG KY A D V Sbjct: 7591 VRKLEATTLVTCGQSSRLECRATGSPVIIFKWFKD--EMEITPG---PKY-TMAADDLVA 7644 Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414 L I +S VC A + AGS RG +TV + PP + + S + + Sbjct: 7645 SLEIVQCTLAES-GDYVCVASSEAGSDCCRGTVTVKA----PPSFVRSLESKDVVKGSEL 7699 Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT-NDGTLVLKDL--DKSDSGTYTCVASS 471 + + P + G+A+ + R +T D + L+ L + D G Y C + Sbjct: 7700 MLEGQVSGSAPFTVTLCK-NGKAIRNDKRHRITVKDELIALQVLAVEAGDVGLYQCTVEN 7758 Query: 472 RHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNN 528 + G+ + + P P+ + ++SSL G + + +SW ++N Sbjct: 7759 QVGRVSCDCHVTLKDP--PSF-VQKLENLSSLVGSEVSLLCVLKGSEPMVVSWMKDN 7812 Score = 93.1 bits (221), Expect = 4e-17 Identities = 120/529 (22%), Positives = 201/529 (37%), Gaps = 29/529 (5%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P ++ D++V ATL+ + + + W G LV + L Sbjct: 6742 EHPTVVTALEDISVDEDSKATLSTTI--THAAKVNWLFNGQLVKPGKEFRCSKEKDTYTL 6799 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 + G Y CEA N G + + V + FRL+ + + G + C Sbjct: 6800 VISKVVKEMHQGEYVCEAENEAGKTTTSSRLTVVPRVPPVFRLKIAALEINVGSSAKFYC 6859 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGT 188 +P+ N W K+G + R+ + L + + D+G Y C N G Sbjct: 6860 -EVSDAPDVNFRWYKSGVEIKQSEKYRIVSSSTSSALELVSPVKADSGEYSCKVSNPHGV 6918 Query: 189 RESAIATLKIHI-KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247 A + + + P ++ PE + G FQC + G DV+W + + Sbjct: 6919 DTCAASLIVTELYPPVFVSKPEPMTLFVGKEAVFQCSLTGSSPMDVVWHKDNLAISSEGK 6978 Query: 248 RVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305 V D SL + ++ LA +G Y C+A NSVG + S L V D PS + + Sbjct: 6979 YVMKSDKNKYSLHIQSLELAHQGVYLCKASNSVGTATFSTELWVIDKPSFVKPFDQASAA 7038 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365 + R C T+ W+ +G + S D + D V V+ I D Sbjct: 7039 VNDPVRLECQVNEDTGVTIIWTRDGKKV----HQSMD--CKLSFEDKVAVVEIPKAKLKD 7092 Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425 S VC+A N AGSS + V PP I + + L K + I Sbjct: 7093 S-GKYVCTATNEAGSSSCEAVVMV----QEPPSIRKELQTVEAL--KGGPAYLEYEIAGT 7145 Query: 426 EPI-IAWYFEGEALIQNHRRNVTNDGTLVLKDL---DKSDSGTYTCVASSRHGKYVWSGA 481 P I W + + + + N+ + +L ++ + +D G Y V S+ GK Sbjct: 7146 APFEITWSKNRKPITSDKKYNIISQQSLSRLEILTFESADVGDYQMVVSNEVGKVSTKAV 7205 Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTS-VTLSWSQNNK 529 + P P+ R V+++ G K + V +S +T+ W ++++ Sbjct: 7206 AKLKEP--PSF-TKRVDSVTAVLGTTVK-LQGTVKGSSPITVKWMKDSE 7250 Score = 68.5 bits (160), Expect = 1e-09 Identities = 107/465 (23%), Positives = 179/465 (38%), Gaps = 43/465 (9%) Query: 44 RWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH-SDAGVYWCEATNSYGTARSRNATLH 102 +W K GV V S + L T VH D G Y A ++ A S N + Sbjct: 2754 KWLKNGVEVKSSDRCQVRSRQLTHTL--TIRNVHFGDGGEYQFVAGSA---ATSANLFVE 2808 Query: 103 VAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG 162 V+ EF + + + + + EC P V W K+GQ L + + + Sbjct: 2809 ARVI--EFTRKIKDIKIIEKKKAIFEC--EVSEPNIQVMWMKDGQELDLSEERYVTTAEK 2864 Query: 163 --GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVT 220 L+IQ R +DAG Y +A ++ + + I I P D+ T Sbjct: 2865 YVHRLMIQTVRMSDAGEYSVVAGSSVSKAQLVVEGRDIRIAP---PAERDITVLEKHRAT 2921 Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMPLGR----VKVLDDGSLRLDNVILADEGEYSCEAEN 276 + V D DV R G + L V + + + +D GEY+ A Sbjct: 2922 IEFEVNED---DVEGRWLKNGAELSLEERFSYVVIRKVHRITISETFRSDAGEYTFIAGK 2978 Query: 277 SVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF 336 + +V+ + + +PP I +VE G +ARF+ +G P+P + W N ++ Sbjct: 2979 NRSSVNLR--VNIPEPPQILRHMEPQSVEVGKLARFSVEVSGVPQPQVSW--YKNSQMLS 3034 Query: 337 PGMSRDKYHATAVFDGVTVLTINDTD--------KNDSRNTIVCSAVNYAGSSFVRGKLT 388 G + K+ A + ++ + D KND +++N S V L Sbjct: 3035 AGF-KCKFLCEANQHSLLLIEVFPEDAAVYSCEAKNDYGAASSTASLNVEVSEVVSPDLA 3093 Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH--RRNV 446 PP+IT+ S+ + A F C + + I+W+ + + + Q+ R + Sbjct: 3094 AAV----APPVITSPISSTSAREGEPARFHC-RVHGDDVKISWFHKEKEIKQSEFFRMSQ 3148 Query: 447 TNDG-TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490 D L + + D G Y+CVA++ G S L +D P Sbjct: 3149 FEDSCQLEISRVYPEDEGEYSCVATNSGGTASCSATLTLDGQTLP 3193 Score = 66.9 bits (156), Expect = 3e-09 Identities = 77/287 (26%), Positives = 113/287 (39%), Gaps = 27/287 (9%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 D+TV AT+ RW K G + + S + + + + SD Sbjct: 2911 DITVLEKHRATIEFEVNEDDVEG-RWLKNGAELSLEERFSYVVIRKVHRITISE-TFRSD 2968 Query: 80 AGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138 AG Y A + + R N +LR +EP+S + + +E G P+P Sbjct: 2969 AGEYTFIAGKNRSSVNLRVNIPEPPQILRH---MEPQSVEVGKLARFSVEV---SGVPQP 3022 Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196 V W KN Q +L G L + +L++ + DA Y C A+N G S A+L Sbjct: 3023 QVSWYKNSQ-MLSAGFKCKFLCEANQHSLLLIEVFPEDAAVYSCEAKNDYGAASST-ASL 3080 Query: 197 KIHIK------------PYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 + + P +IT P A+ G F CRV GD + + + Sbjct: 3081 NVEVSEVVSPDLAAAVAPPVITSPISSTSAREGEPARFHCRVHGDDVKISWFHKEKEIKQ 3140 Query: 244 MPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 R+ +D L + V DEGEYSC A NS G S S LT+ Sbjct: 3141 SEFFRMSQFEDSCQLEISRVYPEDEGEYSCVATNSGGTASCSATLTL 3187 Score = 62.9 bits (146), Expect = 5e-08 Identities = 76/308 (24%), Positives = 118/308 (38%), Gaps = 25/308 (8%) Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG---LFFLRATHG 74 P +VT+ L C GS + W K + S + +I L L+A G Sbjct: 9500 PQEVTMG--DSIELECHMTGSAPIKVTWSKDHKDIRSGGNYNISCVDNTPHLTILKADKG 9557 Query: 75 RVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEP-ESKQSAQGDTVVLECLPP 132 D G Y+C A N G S + T+ F +P E + +G V +E Sbjct: 9558 ----DTGKYFCHAMNDVGKVSCSSDVTVKERKNPPVFTKKPSEHMEDTEGRLVKIEGRVS 9613 Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192 P ++K++ + D + L I+ + TD+GRY C A N AG R S Sbjct: 9614 GSQPMSVSWYKEDAEIHSSDKYDISFKSNVAVLCIKSSHVTDSGRYTCQASNEAG-RASC 9672 Query: 193 IATLKIHI--KPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGGGNMP 245 T+ I KP + P + + G ++ +C V G + W + GGN Sbjct: 9673 CTTVGISEAKKPPVFDVPLKPLTVDEGEKMSLKCHVCGSAPLIIQWMKDRKELTSGGNTK 9732 Query: 246 LGRVKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303 + DG+ L + D G+Y C+A N G+ + + V P L+P Sbjct: 9733 IS----FTDGTACLEISPASRKDAGDYLCKATNDAGSEFSKAKVAVRQKPGAALAPAEAP 9788 Query: 304 VESGNVAR 311 + V R Sbjct: 9789 AVAAPVKR 9796 Score = 60.1 bits (139), Expect = 4e-07 Identities = 44/129 (34%), Positives = 61/129 (47%), Gaps = 7/129 (5%) Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM-PLGRVKV-LDDGS--LRLDNVIL 264 + VVA GS+ TF+ +V G P+P+V W R ++ L V++ DG LRL V Sbjct: 13 QSVVALEGSAATFEAQVSGSPVPEVSWFRDGQVLSVAALPGVQISFSDGRAVLRLTAVTA 72 Query: 265 ADEGEYSCEAENSVGAVSASGYLTV---YDPPSINLSPNSVNVESGNVARFTCTATGRPE 321 A G YS A N G +++ L V PP+ S V G+ R TG P Sbjct: 73 AHSGRYSVRATNGAGQATSTAELLVTVETAPPNFVQRLQSSTVRQGSQVRLDVRVTGIPS 132 Query: 322 PTMFWSVEG 330 PT+ + EG Sbjct: 133 PTVKFYREG 141 Score = 59.3 bits (137), Expect = 6e-07 Identities = 45/153 (29%), Positives = 71/153 (46%), Gaps = 4/153 (2%) Query: 140 VYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198 V W+K+G+ + ++ D ++ I+ +DAGRY C NAAG+ ES+ +L++ Sbjct: 8521 VEWQKDGKKIFSGVKHKLIQQDNSVSVEIEQLEPSDAGRYSCKLTNAAGSCESS-GSLQV 8579 Query: 199 HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-- 256 P ++ PE A + V F+ G P V W + LD S Sbjct: 8580 KEPPSFVSPPEPQSAVPNAKVRFKGTFKGTPPFTVQWFKDDRELMTGPTCFTGLDGLSCF 8639 Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 L L +V ++ G YSC+ N+ G+ S LTV Sbjct: 8640 LELYSVNISQSGVYSCQVSNAAGSARCSANLTV 8672 Score = 58.4 bits (135), Expect = 1e-06 Identities = 67/224 (29%), Positives = 96/224 (42%), Gaps = 11/224 (4%) Query: 8 SGEAPYIIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHR-SILPAG 64 S +AP QPL VA AT + GSP P + W++ G VL V+ I + Sbjct: 2 STQAP-TFTQPLQSVVALEGSAATFEAQVSGSPVPEVSWFRDGQVLSVAALPGVQISFSD 60 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATL-HVAVLREEFRLEPESKQSAQGD 123 G LR T + +G Y ATN G A S L V F +S QG Sbjct: 61 GRAVLRLT-AVTAAHSGRYSVRATNGAGQATSTAELLVTVETAPPNFVQRLQSSTVRQGS 119 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCI 181 V L+ + G P P V + + G + D ++ L DG +L+I +A D+G Y Sbjct: 120 QVRLD-VRVTGIPSPTVKFYREGAEIQSSADFQI-LQDGDLYSLLIAEAFPEDSGTYSVT 177 Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV 225 A N++G R ++ A L + + + T V T T + RV Sbjct: 178 AANSSG-RATSTAELLVQGEEAMPTKKTKTVVSTSEIRTSKARV 220 Score = 58.4 bits (135), Expect = 1e-06 Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 2/92 (2%) Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL 259 + P LI G ++V G S+T +C++GG P P ++W R + DG RL Sbjct: 590 VPPTLIVGLKNVTVTEGESLTLECQIGGQPTPVIMWFREDYQIESSIDFHTSYTDGIARL 649 Query: 260 --DNVILADEGEYSCEAENSVGAVSASGYLTV 289 D G +SC A N G +S S YL V Sbjct: 650 VIREAFAEDSGRFSCTATNEAGTISTSCYLLV 681 Score = 54.0 bits (124), Expect = 2e-05 Identities = 72/281 (25%), Positives = 117/281 (41%), Gaps = 23/281 (8%) Query: 218 SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEA 274 S+TF V G P P+V W + + R+K+ DG SL + +V AD+GEY CEA Sbjct: 5190 SLTFFAEVFGLPSPEVKWFCNKTQ-LVEDDRIKMERDGDSISLTVLDVTKADQGEYICEA 5248 Query: 275 ENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334 N+VG + S L V + L P V +V F S + Sbjct: 5249 VNNVGE-ARSVTLVVVLSQEMRLMPPPPAVTHQHVMEFDVEDNDT-------SRSPSPQE 5300 Query: 335 IFPGMSRDKYHATAVFDGVTVLTIND-TDKNDSRNT---IVCSAVNYAGSSFV---RGKL 387 I + D+ V ++TI + T N S ++ S FV L Sbjct: 5301 ILLEVELDENEVKEFEKQVKIITIPEYTADNKSMIVSLDVLPSVYEEGAVDFVTHEHDDL 5360 Query: 388 TVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNV- 446 + + PP N + P + +F C+ + TP PI++W+ + + N ++ V Sbjct: 5361 KIAFEVTEMPPRFINPICDMETPEGTTILFECSLMGTPSPIVSWFKGDKKIPPNSKKYVH 5420 Query: 447 TNDG---TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 +++G L + + DSG Y C A + G+ + +L+V Sbjct: 5421 SSEGDNHILKICTVTTQDSGVYICRAINVVGETLSRASLVV 5461 Score = 51.2 bits (117), Expect = 2e-04 Identities = 38/116 (32%), Positives = 54/116 (46%), Gaps = 7/116 (6%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS--DTHRSILPAGGLFFL 69 P +I +VTV + TL C+ GG P+P I W++ + S D H S + Sbjct: 592 PTLIVGLKNVTVTEGESLTLECQIGGQPTPVIMWFREDYQIESSIDFHTSYTDGIARLVI 651 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDT 124 R D+G + C ATN GT S + L V V E E+R EP ++ + G T Sbjct: 652 REAFA---EDSGRFSCTATNEAGTI-STSCYLLVKVSEEIEYREEPVAEVTEVGVT 703 Score = 50.4 bits (115), Expect = 3e-04 Identities = 32/78 (41%), Positives = 42/78 (53%), Gaps = 5/78 (6%) Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG--RVKVLDDG--SLRLDNVILADEGEYS 271 G VTF CR+ G PLP + W + G P +++ L DG SLRL V+ DEG Y+ Sbjct: 968 GMGVTFHCRMSGKPLPKIAWFKD-GQRLRPSDHYQMETLQDGRASLRLAQVLPEDEGVYT 1026 Query: 272 CEAENSVGAVSASGYLTV 289 A N +G +SG L V Sbjct: 1027 AFAANVLGNAVSSGKLYV 1044 Score = 48.0 bits (109), Expect = 0.002 Identities = 31/80 (38%), Positives = 42/80 (52%), Gaps = 7/80 (8%) Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL---DDGS--LRLDNVILADEGEY 270 G+ V F +V GDP+PDV W + G + GR V+ DGS L L ++ D G Y Sbjct: 5741 GTEVFFHYQVSGDPVPDVKWYK--GAFQVQPGRNCVIISNPDGSGCLSLKSLKQEDSGMY 5798 Query: 271 SCEAENSVGAVSASGYLTVY 290 C A N+ G S+S L V+ Sbjct: 5799 MCRASNTFGEASSSAELAVF 5818 Score = 47.6 bits (108), Expect = 0.002 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 4/90 (4%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGGGNMPLGRVKVLDDGSL 257 P+ + P G SV F+C+VGG+P P V+W+++ G + + + L Sbjct: 740 PFFMKKPAAQKLVEGGSVVFECQVGGNPKPHVIWKKNGLPLTTGYRYRVAYKRETGECKL 799 Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYL 287 + D GEY+ +N G VSAS L Sbjct: 800 EISMTFADDAGEYAIFVKNPHGEVSASASL 829 Score = 47.6 bits (108), Expect = 0.002 Identities = 119/468 (25%), Positives = 177/468 (37%), Gaps = 56/468 (11%) Query: 15 IEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73 I +PL DVTVA Q A L C + + RW K G V + G + L T Sbjct: 2376 ITRPLQDVTVAESQTAVLECEVANAEAEG-RWMKEGQPVDFSENVVSEVKGAVRRLTITI 2434 Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133 R D G Y + NS TA N + +++ R + ++ T+ L + Sbjct: 2435 TR-PQDVGEYSYQVANSKTTA---NLRVEAVKIKKTLRNQTVTETQDAVFTLELTHADVK 2490 Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGTRES 191 GS W KNG L D DG +L I++ D Y + Sbjct: 2491 GS-----QWIKNGVELQ-SSDKYEISSDGMVQSLKIRNCNTQDESVYSFKLGKLSANARL 2544 Query: 192 AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251 + T+KI I +DV + +F+ + D +P V W G P R K+ Sbjct: 2545 NVETIKI------IKKTKDVTTLMDGTASFEMSLSHDDVP-VKW-MFKGAELKPSDRCKI 2596 Query: 252 LDD---GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGN 308 L + L L NV ++ GEY+ VG + S LTV + I +V Sbjct: 2597 LRERRAHKLILQNVNSSNAGEYTA----VVGHLQCSATLTV-EALQIVKPMKDASVAETQ 2651 Query: 309 VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368 A F C + P+ W +G + MS +K+ V + L I +T K+DS Sbjct: 2652 AATFECEVSHFNVPST-WLKDG----VEIEMS-EKFR-IVVQGKLHQLKIVNTSKDDSAE 2704 Query: 369 -TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427 T +C G+ V LTV+ P +IT+ + + F T E Sbjct: 2705 YTFIC------GNDRVSATLTVS------PVLITSMLKDLNAQERDTITFEVTV--NHEG 2750 Query: 428 I-IAWYFEGEALIQNHRRNVTN---DGTLVLKDLDKSDSGTYTCVASS 471 I W G + + R V + TL ++++ D G Y VA S Sbjct: 2751 ITYKWLKNGVEVKSSDRCQVRSRQLTHTLTIRNVHFGDGGEYQFVAGS 2798 Score = 47.2 bits (107), Expect = 0.003 Identities = 76/324 (23%), Positives = 111/324 (34%), Gaps = 47/324 (14%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P I+ +V + A + G P P + WYK ++ + L L Sbjct: 2991 EPPQILRHMEPQSVEVGKLARFSVEVSGVPQPQVSWYKNSQMLSAGFKCKFLCEANQHSL 3050 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHV-----------AVLREEFRLEPESKQ 118 DA VY CEA N YG A S A+L+V A + P S Sbjct: 3051 LLIE-VFPEDAAVYSCEAKNDYGAA-SSTASLNVEVSEVVSPDLAAAVAPPVITSPISST 3108 Query: 119 SA-QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR 177 SA +G+ C G ++ K + + D L I D G Sbjct: 3109 SAREGEPARFHC-RVHGDDVKISWFHKEKEIKQSEFFRMSQFEDSCQLEISRVYPEDEGE 3167 Query: 178 YQCIARNAAGTR--------------ESAIATLKIHIKPYLIT------GPEDVVAQTGS 217 Y C+A N+ GT E+ A + H+ L + G + Q Sbjct: 3168 YSCVATNSGGTASCSATLTLDGQTLPEAGAAVPQWHVSTSLTSIKKAPIGQKPTFIQPIR 3227 Query: 218 SVT--------FQCRVGGDPLPDVLW----RRSAGGGNMPLGRVKVLDDGSLRLDNVILA 265 S T F V G P P+V W R N+ + + +L + + Sbjct: 3228 SCTVAHGAVARFHACVSGMPKPEVSWFHNQRPIQPTTNVVFHFEEATNTATLIIVDAFTE 3287 Query: 266 DEGEYSCEAENSVGAVSASGYLTV 289 G+Y+C A NS G + S LT+ Sbjct: 3288 HAGQYTCRAANSAGEAACSATLTI 3311 Score = 46.4 bits (105), Expect = 0.005 Identities = 48/197 (24%), Positives = 76/197 (38%), Gaps = 14/197 (7%) Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII--FPGMSRDKYHATAVF 350 P+ SV G+ A F +G P P + W +G + PG+ + Sbjct: 6 PTFTQPLQSVVALEGSAATFEAQVSGSPVPEVSWFRDGQVLSVAALPGVQ------ISFS 59 Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410 DG VL + S V A N AG + +L VT + PP + T+ Sbjct: 60 DGRAVLRLTAVTAAHSGRYSV-RATNGAGQATSTAELLVTVET--APPNFVQRLQSSTVR 116 Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTC 467 S P P + +Y EG + + + DG +L++ + DSGTY+ Sbjct: 117 QGSQVRLDVRVTGIPSPTVKFYREGAEIQSSADFQILQDGDLYSLLIAEAFPEDSGTYSV 176 Query: 468 VASSRHGKYVWSGALLV 484 A++ G+ + LLV Sbjct: 177 TAANSSGRATSTAELLV 193 Score = 46.0 bits (104), Expect = 0.006 Identities = 23/71 (32%), Positives = 35/71 (49%) Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315 S+ ++ + +D G YSC+ N+ G+ +SG L V +PPS P + RF T Sbjct: 8546 SVEIEQLEPSDAGRYSCKLTNAAGSCESSGSLQVKEPPSFVSPPEPQSAVPNAKVRFKGT 8605 Query: 316 ATGRPEPTMFW 326 G P T+ W Sbjct: 8606 FKGTPPFTVQW 8616 Score = 44.8 bits (101), Expect = 0.015 Identities = 33/106 (31%), Positives = 45/106 (42%), Gaps = 4/106 (3%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68 G P ++ + V + T G PSP ++W+ +V D + G Sbjct: 5171 GVPPAFLKPLMKKRVCENDSLTFFAEVFGLPSPEVKWFCNKTQLVEDDRIKMERDGDSIS 5230 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP 114 L +D G Y CEA N+ G ARS TL V VL +E RL P Sbjct: 5231 LTVLDV-TKADQGEYICEAVNNVGEARS--VTL-VVVLSQEMRLMP 5272 Score = 44.0 bits (99), Expect = 0.025 Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 2/69 (2%) Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQ 179 +G+++ LEC G P P + W + + D DG LVI++A D+GR+ Sbjct: 605 EGESLTLEC-QIGGQPTPVIMWFREDYQIESSIDFHTSYTDGIARLVIREAFAEDSGRFS 663 Query: 180 CIARNAAGT 188 C A N AGT Sbjct: 664 CTATNEAGT 672 Score = 44.0 bits (99), Expect = 0.025 Identities = 24/80 (30%), Positives = 36/80 (45%) Query: 13 YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRAT 72 + IE+P V V AT + GG P P+++W KG ++ R + G Sbjct: 9801 FFIEEPKAVRVTEKSTATFMTKVGGDPIPSVKWMKGKWRQMTHGGRISVDQKGQEAKLEI 9860 Query: 73 HGRVHSDAGVYWCEATNSYG 92 SD+G Y C A+N +G Sbjct: 9861 REVTRSDSGQYRCIASNKHG 9880 Score = 43.2 bits (97), Expect = 0.044 Identities = 33/102 (32%), Positives = 44/102 (43%), Gaps = 8/102 (7%) Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352 P I L P V G++ARF C TG P P + W + G + R + H +DG Sbjct: 1572 PEIVLLPEPARVFEGDIARFRCRVTGYPAPKVNWYLNGQ---LIRKSKRYRLH----YDG 1624 Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394 + L I D DS V A N G++ KL V +D Sbjct: 1625 IYYLEIVDIKSYDSGEVRVV-ADNPLGTTEHTVKLEVQQKED 1665 Score = 43.2 bits (97), Expect = 0.044 Identities = 44/171 (25%), Positives = 72/171 (42%), Gaps = 8/171 (4%) Query: 43 IRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLH 102 + W K G + S ++ + SDAG Y C+ TN+ G+ S + Sbjct: 8521 VEWQKDGKKIFSGVKHKLIQQDNSVSVEIEQLEP-SDAGRYSCKLTNAAGSCESSGS--- 8576 Query: 103 VAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG 162 + V + P QSA + V +G+P V W K+ + L+ G + +DG Sbjct: 8577 LQVKEPPSFVSPPEPQSAVPNAKVRFKGTFKGTPPFTVQWFKDDRELM-TGPTCFTGLDG 8635 Query: 163 GN--LVIQDARQTDAGRYQCIARNAAGT-RESAIATLKIHIKPYLITGPED 210 + L + + +G Y C NAAG+ R SA T+K+ + G +D Sbjct: 8636 LSCFLELYSVNISQSGVYSCQVSNAAGSARCSANLTVKVAVLELQSAGFDD 8686 Score = 43.2 bits (97), Expect = 0.044 Identities = 47/211 (22%), Positives = 74/211 (35%), Gaps = 16/211 (7%) Query: 20 DVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS 78 D +V + A C P + WYKG + S I +G LR + S Sbjct: 10008 DQSVFTGKEAEFQCEVTINYPEITLSWYKGTQKLDSSDKYDISISGDRHLLRIRRCQT-S 10066 Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138 D G Y +A+ + V+ E + +G + L C P Sbjct: 10067 DQGNYRVVCGPHISSAK-------LTVMEAEVEKHLQDTSGKEGQSCTLSC--QLSIPNV 10117 Query: 139 NVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197 W KNG+ L G + L+I D + D GRY C ++ + + + + Sbjct: 10118 QAQWFKNGKRLEMKGKFTSEVKHKIQKLLISDLKPEDQGRYTCQYQSLESSADLWVEAEQ 10177 Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228 IH + ++ S TF+C V D Sbjct: 10178 IHFTKRI----HNIEVNERQSATFECEVSFD 10204 Score = 42.3 bits (95), Expect = 0.078 Identities = 27/87 (31%), Positives = 37/87 (42%), Gaps = 1/87 (1%) Query: 107 REEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV 166 + E L PE + +GD C G P P V W NGQ + R+H L Sbjct: 1571 KPEIVLLPEPARVFEGDIARFRCRVT-GYPAPKVNWYLNGQLIRKSKRYRLHYDGIYYLE 1629 Query: 167 IQDARQTDAGRYQCIARNAAGTRESAI 193 I D + D+G + +A N GT E + Sbjct: 1630 IVDIKSYDSGEVRVVADNPLGTTEHTV 1656 Score = 41.1 bits (92), Expect = 0.18 Identities = 26/82 (31%), Positives = 44/82 (53%), Gaps = 8/82 (9%) Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTL------LFDGDSRMHLVDGGNLVIQDARQTD 174 +G+ V L+C SP P++ W N +TL DS+MH+ +L+I ++ D Sbjct: 3380 EGEPVELKC-ELVASPPPSILWFHNNKTLGKARRRRICSDSQMHM-HTTSLIIDRVKEKD 3437 Query: 175 AGRYQCIARNAAGTRESAIATL 196 +G Y+ +A N+ G+ ES + L Sbjct: 3438 SGSYKVMAINSEGSAESTASLL 3459 Score = 40.7 bits (91), Expect = 0.24 Identities = 31/90 (34%), Positives = 45/90 (50%), Gaps = 5/90 (5%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM-HLVDGG--NLV 166 F +P +++ +G +VV EC G+P+P+V WKKNG L R+ + + G L Sbjct: 742 FMKKPAAQKLVEGGSVVFEC-QVGGNPKPHVIWKKNGLPLTTGYRYRVAYKRETGECKLE 800 Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATL 196 I DAG Y +N G SA A+L Sbjct: 801 ISMTFADDAGEYAIFVKNPHG-EVSASASL 829 Score = 39.9 bits (89), Expect = 0.41 Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 3/91 (3%) Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG---EALIQNHRRNVTNDGTLV 453 PP + G N T+ C P P+I W+ E E+ I H LV Sbjct: 591 PPTLIVGLKNVTVTEGESLTLECQIGGQPTPVIMWFREDYQIESSIDFHTSYTDGIARLV 650 Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 +++ DSG ++C A++ G S LLV Sbjct: 651 IREAFAEDSGRFSCTATNEAGTISTSCYLLV 681 Score = 39.1 bits (87), Expect = 0.72 Identities = 23/88 (26%), Positives = 43/88 (48%), Gaps = 3/88 (3%) Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT--DA 175 ++ +G T++ EC G+P P V W K + + + +H +G N +++ T D+ Sbjct: 5381 ETPEGTTILFEC-SLMGTPSPIVSWFKGDKKIPPNSKKYVHSSEGDNHILKICTVTTQDS 5439 Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPY 203 G Y C A N G S + + ++ K + Sbjct: 5440 GVYICRAINVVGETLSRASLVVVNAKAF 5467 Score = 39.1 bits (87), Expect = 0.72 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 1/84 (1%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 +T E P I E+P + V P +L+C+ GSP+ ++W K G + S ++ Sbjct: 8424 LTVQEPPQITEKPEVIKVTVGDPVSLDCKVTGSPALKVKWMKEGKELQSIRQHKLVFENN 8483 Query: 66 LFFLRATHGRVHSDAGVYWCEATN 89 + L+ D G Y E N Sbjct: 8484 ISSLK-IQAAEREDEGEYILEVAN 8506 Score = 38.7 bits (86), Expect = 0.96 Identities = 30/119 (25%), Positives = 45/119 (37%), Gaps = 6/119 (5%) Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350 + P+ N + + G F C +G+P P + W +G R + P D Y + Sbjct: 952 EQPAFNTPVKNYRIMEGMGVTFHCRMSGKPLPKIAWFKDGQR--LRPS---DHYQMETLQ 1006 Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409 DG L + D A N G++ GKL V PP T P+ Q + Sbjct: 1007 DGRASLRLAQVLPED-EGVYTAFAANVLGNAVSSGKLYVEPSGAFPPQRYTAQPAVQRI 1064 Score = 38.7 bits (86), Expect = 0.96 Identities = 22/86 (25%), Positives = 34/86 (39%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I D+ C G+PSP + W+KG + ++ + + + G + Sbjct: 5371 PRFINPICDMETPEGTTILFECSLMGTPSPIVSWFKGDKKIPPNSKKYVHSSEGDNHILK 5430 Query: 72 THGRVHSDAGVYWCEATNSYGTARSR 97 D+GVY C A N G SR Sbjct: 5431 ICTVTTQDSGVYICRAINVVGETLSR 5456 Score = 38.7 bits (86), Expect = 0.96 Identities = 25/78 (32%), Positives = 40/78 (51%), Gaps = 9/78 (11%) Query: 34 RAGGSPSPAIRWYKGGVLVVSDTHRSIL--PAG-GLFFLRATHGRVHSDAGVYWCEATNS 90 + G P P ++WYKG V + I+ P G G L++ D+G+Y C A+N+ Sbjct: 5749 QVSGDPVPDVKWYKGAFQVQPGRNCVIISNPDGSGCLSLKSLK---QEDSGMYMCRASNT 5805 Query: 91 YGTARSRNATLHVAVLRE 108 +G A S + +AV +E Sbjct: 5806 FGEASS---SAELAVFKE 5820 Score = 37.9 bits (84), Expect = 1.7 Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 5/105 (4%) Query: 386 KLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEAL--IQNH 442 +L VT+ + N P ++ M V F C P P IAW+ +G+ L ++ Sbjct: 941 ELMVTAAEGEAEQPAFNTPVKNYRIMEGMGVTFHCRMSGKPLPKIAWFKDGQRLRPSDHY 1000 Query: 443 RRNVTNDG--TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485 + DG +L L + D G YT A++ G V SG L V+ Sbjct: 1001 QMETLQDGRASLRLAQVLPEDEGVYTAFAANVLGNAVSSGKLYVE 1045 Score = 37.9 bits (84), Expect = 1.7 Identities = 56/219 (25%), Positives = 81/219 (36%), Gaps = 34/219 (15%) Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--------------- 52 S EAP I+E+ TVA R G P P +W+K G+LV Sbjct: 1804 SMEAPRILERIQSKTVAPMDEVRFRVRVVGRPEPECQWFKNGILVEKTERVYWFWPEDNV 1863 Query: 53 ---------VSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103 D+ ++ A + ++H + + T G+ S L Sbjct: 1864 CELVIRDVTAEDSASIMVKANNVAGEASSHAFLLVQGNAMLQDDTRCAGSCVSLPGFLIA 1923 Query: 104 AVLREEFRLEPESKQSAQGDTVV-LECLPPRGSPEPNVYWKKNGQTLLFDGDS-RMH--- 158 A F E + + DT+V EC P V W KN T +F GD RMH Sbjct: 1924 AKAAVSFTQHLEDATANEKDTMVTFEC--ETSEPFIKVKWLKN-NTEIFSGDKYRMHSDR 1980 Query: 159 LVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197 V +++I D R D Y C+ + R SA T++ Sbjct: 1981 KVHFLSVLIIDLR--DDAEYTCVLADDESVRTSARLTVE 2017 Score = 37.1 bits (82), Expect = 2.9 Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 4/100 (4%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I+ P V A CR G P+P + WY G L + + R L G+++L Sbjct: 1572 PEIVLLPEPARVFEGDIARFRCRVTGYPAPKVNWYLNGQL-IRKSKRYRLHYDGIYYLEI 1630 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR 111 + + D+G A N GT L V +E+FR Sbjct: 1631 VDIKSY-DSGEVRVVADNPLGTT-EHTVKLEVQ-QKEDFR 1667 Score = 37.1 bits (82), Expect = 2.9 Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 7/85 (8%) Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL-----DDGSLRLDNVIL 264 D+ G+++ F+C + G P P V W + G +P K + D+ L++ V Sbjct: 5379 DMETPEGTTILFECSLMGTPSPIVSWFK--GDKKIPPNSKKYVHSSEGDNHILKICTVTT 5436 Query: 265 ADEGEYSCEAENSVGAVSASGYLTV 289 D G Y C A N VG + L V Sbjct: 5437 QDSGVYICRAINVVGETLSRASLVV 5461 Score = 36.7 bits (81), Expect = 3.9 Identities = 25/107 (23%), Positives = 45/107 (42%), Gaps = 7/107 (6%) Query: 385 GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR 444 G + TS P T Q++ C + +P P I W+ + L + RR Sbjct: 3354 GCSSTTSGTGNVKPSFTKKLKFQSVLEGEPVELKCELVASPPPSILWFHNNKTLGKARRR 3413 Query: 445 NVTNDG-------TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 + +D +L++ + + DSG+Y +A + G + +LLV Sbjct: 3414 RICSDSQMHMHTTSLIIDRVKEKDSGSYKVMAINSEGSAESTASLLV 3460 Score = 36.3 bits (80), Expect = 5.1 Identities = 21/81 (25%), Positives = 34/81 (41%), Gaps = 3/81 (3%) Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTC 467 + M+ F C P P + W +G L N ++ N L + GTY C Sbjct: 4364 VGEMSEFTCQFHGDPLPTVTWLKDGHPLTNNPDFDIIDRANRSKLTVFYPTADHEGTYDC 4423 Query: 468 VASSRHGKYVWSGALLVDSPI 488 + +++HGK + S L + I Sbjct: 4424 IITNKHGKSLCSATLEIADKI 4444 Score = 35.9 bits (79), Expect = 6.7 Identities = 25/89 (28%), Positives = 38/89 (42%), Gaps = 7/89 (7%) Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 PP++ + +V V G C G+P P + W E + S +H T+ D Sbjct: 591 PPTLIVGLKNVTVTEGESLTLECQIGGQPTPVIMWFRED-----YQIESSIDFH-TSYTD 644 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGS 380 G+ L I + DS C+A N AG+ Sbjct: 645 GIARLVIREAFAEDS-GRFSCTATNEAGT 672 Score = 35.9 bits (79), Expect = 6.7 Identities = 23/101 (22%), Positives = 41/101 (40%), Gaps = 2/101 (1%) Query: 4 DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63 D G AP +++ + + + C+ G P P + W K G + ++ I+ Sbjct: 4343 DAAAGGAAPVFVKEMCPLKARVGEMSEFTCQFHGDPLPTVTWLKDGHPLTNNPDFDIIDR 4402 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA 104 L + + G Y C TN +G + +ATL +A Sbjct: 4403 ANRSKLTVFYPTADHE-GTYDCIITNKHGKSLC-SATLEIA 4441 Score = 35.9 bits (79), Expect = 6.7 Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 3/45 (6%) Query: 6 VTSGEAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGG 49 VT +II PL ++T A P L C G+P+P WYK G Sbjct: 5577 VTESPPKFII--PLTNITAAAGTPVILQCLVSGTPNPTAEWYKDG 5619 Score = 35.5 bits (78), Expect = 8.9 Identities = 25/68 (36%), Positives = 30/68 (44%), Gaps = 2/68 (2%) Query: 30 TLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88 T +CR G P P I W+K G L SD ++ G LR + D GVY A Sbjct: 972 TFHCRMSGKPLPKIAWFKDGQRLRPSDHYQMETLQDGRASLRLAQ-VLPEDEGVYTAFAA 1030 Query: 89 NSYGTARS 96 N G A S Sbjct: 1031 NVLGNAVS 1038 >UniRef50_Q8WZ42 Cluster: Titin; n=65; Eukaryota|Rep: Titin - Homo sapiens (Human) Length = 34350 Score = 141 bits (342), Expect = 9e-32 Identities = 138/492 (28%), Positives = 199/492 (40%), Gaps = 32/492 (6%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E PY IE V +PATL C+ G+P I WYK + S + + L Sbjct: 7945 EPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASL 8004 Query: 70 RATHGRVHSDAGVYWCEATNSYGT-ARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128 + HSD G Y C+A NS G A S + L F + + G V E Sbjct: 8005 -VINKVDHSDVGEYSCKADNSVGAVASSAVLVIKERKLPPFFARKLKDVHETLGFPVAFE 8063 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAG 187 C GS V W K+G L D + + V L I Q+ G+Y C A N G Sbjct: 8064 CRI-NGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLG 8122 Query: 188 TRES-AIATLKIH-IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGG 241 T S A L H + P+ P V G S TF+C V G + W R G Sbjct: 8123 TASSSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPG 8182 Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSP 299 GN + V+ + +L + V D G+Y+C A N G S S +L V +PP L P Sbjct: 8183 GNYKMTLVE--NTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAHLGVQEPPRFIKKLEP 8240 Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359 + + V+ R+ C G PE + W + K+ + V D V VL ++ Sbjct: 8241 SRI-VKQDEFTRYECKIGGSPEIKVLWYKDETEI-----QESSKFRMSFV-DSVAVLEMH 8293 Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FP 418 + DS C A N AGS+ L V + PPI P + +K V Sbjct: 8294 NLSVEDS-GDYTCEAHNAAGSASSSTSLKV-----KEPPIFRKKP-HPIETLKGADVHLE 8346 Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLV---LKDLDKSDSGTYTCVASSRHGK 475 C TP ++WY + L + + ++ L + ++D +D G Y C A++ G Sbjct: 8347 CELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGS 8406 Query: 476 YVWSGALLVDSP 487 G++ + +P Sbjct: 8407 DTCVGSIALKAP 8418 Score = 138 bits (334), Expect = 9e-31 Identities = 117/463 (25%), Positives = 193/463 (41%), Gaps = 23/463 (4%) Query: 33 CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG 92 C+ GGSP + WYK + + + + L H D+G Y CEA N+ G Sbjct: 8254 CKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEM-HNLSVEDSGDYTCEAHNAAG 8312 Query: 93 TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFD 152 +A S + +L V FR +P ++ +G V LEC +G+P +V W K+ + L Sbjct: 8313 SASS-STSLKVKE-PPIFRKKPHPIETLKGADVHLEC-ELQGTPPFHVSWYKDKRELR-S 8368 Query: 153 GDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED 210 G + + ++ I + D G YQC A N G+ ++ + ++ + P + D Sbjct: 8369 GKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGS-DTCVGSIALKAPPRFVKKLSD 8427 Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL---DDGSLRLDNVILADE 267 + G V Q + G V+W + G + + + +L+ V A+ Sbjct: 8428 ISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANA 8487 Query: 268 GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327 G+Y+C+ +N G L+V +P +I P S+ V +G+ CT G PE + W Sbjct: 8488 GKYTCQIKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWF 8547 Query: 328 VEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387 +G ++ D + + F+ V+ L I + +DS N G L Sbjct: 8548 KDGKE------LTSDNKYKISFFNKVSGLKIINVAPSDS-GVYSFEVQNPVGKDSCTASL 8600 Query: 388 TVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT 447 V+ D PP T S V C +P ++W+ EG + + T Sbjct: 8601 QVS--DRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTT 8658 Query: 448 ---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 N L + L++SDSG YTC+A++ G S L V P Sbjct: 8659 LTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREP 8701 Score = 138 bits (334), Expect = 9e-31 Identities = 136/536 (25%), Positives = 219/536 (40%), Gaps = 30/536 (5%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 +T E P +++P + V T G+P ++ W+KG +V ++ Sbjct: 8696 LTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDS 8755 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV-LREEFRLEPESKQSAQGDT 124 + L S +G Y C +N G A + T H+ + +F +G Sbjct: 8756 VAELELFDVDT-SQSGEYTCIVSNEAGKA---SCTTHLYIKAPAKFVKRLNDYSIEKGKP 8811 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIAR 183 ++LE G+P +V WKKNG + + + L I + DAG+Y C Sbjct: 8812 LILEG-TFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIE 8870 Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 NA+G ++S A + I PY + E V G S + QC++ G P V W + G Sbjct: 8871 NASG-KDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYK--GDTK 8927 Query: 244 M-PLGRVKV---LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSIN 296 + P K+ + +L + V + D GEY C+AENSVG VSAS +LTV + PPS + Sbjct: 8928 LRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFS 8987 Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356 V G F C +G ++ W +G P + T+ D L Sbjct: 8988 RQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQ------TSFLDNTATL 9041 Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416 I TD++ C+A N GS+ +L +T + + PP + + A Sbjct: 9042 NIFKTDRS-LAGQYSCTATNPIGSASSSARLILT--EGKNPPFFDIRLAPVDAVVGESAD 9098 Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRH 473 F C T ++W + + + ++ N L + +DK DSG YTC A + Sbjct: 9099 FECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEV 9158 Query: 474 GKYVWSGALLVDSPINPNIHFFRAAD-VSSLPGPPTKPITHNVTDTSVTLSWSQNN 528 GK + L + + P R ++ V G K +T++W +NN Sbjct: 9159 GKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNN 9214 Score = 137 bits (332), Expect = 1e-30 Identities = 133/499 (26%), Positives = 208/499 (41%), Gaps = 38/499 (7%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 V++ E PY + + + A +L C+ G+P + WYKG DT P Sbjct: 7000 VSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKG------DTKLRPTPEYR 7053 Query: 66 LFFLR--AT--HGRVH-SDAGVYWCEATNSYGTARSRNA-TLHVAVLREEFRLEPESKQS 119 +F AT +V+ +D+G Y C+A NS GTA S+ + L F + + + Sbjct: 7054 TYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQ 7113 Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRY 178 G V L C GS V W ++G L D + + VD L I + +G+Y Sbjct: 7114 TVGLPVTLTCRL-NGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQY 7172 Query: 179 QCIARNAAGTRESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 C A N GT S+ K P+ P + G S F+C V G + W Sbjct: 7173 SCSASNPLGTASSSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWS 7232 Query: 237 RS----AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292 + GGN + V + LR+ V D G+Y+C+A N VG S L+V +P Sbjct: 7233 KDNKEIRPGGNYTITCVG--NTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEP 7290 Query: 293 PS-INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 P + S + G + C +G PE + W N + + KY+ + + + Sbjct: 7291 PKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWF--RNDSELHESW---KYNMSFI-N 7344 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411 V +LTIN+ DS +C A N G + LTV + PP+ T PS Sbjct: 7345 SVALLTINEASAEDS-GDYICEAHNGVGDASCSTALTV-----KAPPVFTQKPSPVGALK 7398 Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN---DGTLVLKDLDKSDSGTYTCV 468 S + C TP + W + + + + + +T+ D +L + +L+ SD G Y C Sbjct: 7399 GSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCK 7458 Query: 469 ASSRHGKYVWSGALLVDSP 487 A++ G S ++ P Sbjct: 7459 ATNEVGSDTCSCSVKFKEP 7477 Score = 137 bits (332), Expect = 1e-30 Identities = 136/532 (25%), Positives = 214/532 (40%), Gaps = 32/532 (6%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E I+E+P + V TL C G+P + +W+K G + SD I + L Sbjct: 8511 EPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGL 8570 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGDTVVL 127 + + SD+GVY E N G S A+L V+ + F + + G +VV+ Sbjct: 8571 KIIN-VAPSDSGVYSFEVQNPVG-KDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVM 8628 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAA 186 EC GSP +V W G + + L D L + ++D+G Y CIA N A Sbjct: 8629 EC-KVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMA 8687 Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 G+ E + A L + P + P+ + TG++VTF V G P V W + + +P Sbjct: 8688 GSDECS-APLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGS-SELVPG 8745 Query: 247 GRVKV-LDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303 R V L+D L L +V + GEY+C N G S + +L + P N + Sbjct: 8746 DRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYS 8805 Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363 +E G T TG P ++ W G + +A+ + + T+ D + Sbjct: 8806 IEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILE-IPSSTVEDAGQ 8864 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423 + C N +G ++ + PP + + A C Sbjct: 8865 YN------CYIENASGKDSCSAQILILE-----PPYFVKQLEPVKVSVGDSASLQCQLAG 8913 Query: 424 TPEPIIAWYFEGEALI------QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477 TPE ++WY +G+ + + H RN N TLV +D +DSG Y C A + G+ Sbjct: 8914 TPEIGVSWY-KGDTKLRPTTTYKMHFRN--NVATLVFNQVDINDSGEYICKAENSVGEVS 8970 Query: 478 WSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529 S L V P + DV G P +++SW ++ K Sbjct: 8971 ASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGK 9022 Score = 127 bits (307), Expect = 2e-27 Identities = 127/507 (25%), Positives = 203/507 (40%), Gaps = 24/507 (4%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 + C+ GSP ++ W+ G + S L + SD+G Y C ATN Sbjct: 8628 MECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCAL-TVNMLEESDSGDYTCIATNM 8686 Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150 G+ +A L V F +P+ G V + +G+P +V W K L+ Sbjct: 8687 AGSDEC-SAPLTVRE-PPSFVQKPDPMDVLTGTNVTFTSIV-KGTPPFSVSWFKGSSELV 8743 Query: 151 FDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209 + L D L + D + +G Y CI N AG + S L I + Sbjct: 8744 PGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAG-KASCTTHLYIKAPAKFVKRLN 8802 Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD---DGSLRLDNVILAD 266 D + G + + G P V W+++ G P R + L + + + D Sbjct: 8803 DYSIEKGKPLILEGTFTGTPPISVTWKKN-GINVTPSQRCNITTTEKSAILEIPSSTVED 8861 Query: 267 EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326 G+Y+C EN+ G S S + + +PP V V G+ A C G PE + W Sbjct: 8862 AGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSW 8921 Query: 327 SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386 +G+ T + P + K H + V L N D NDS +C A N G V Sbjct: 8922 -YKGD-TKLRP-TTTYKMHFR---NNVATLVFNQVDINDS-GEYICKAENSVGE--VSAS 8972 Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGEALIQNHRRN 445 +T + + PP + + + VF C AI EPI ++WY +G+ L + Sbjct: 8973 TFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDC-AISGSEPISVSWYKDGKPLKDSPNVQ 9031 Query: 446 VT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSS 502 + N TL + D+S +G Y+C A++ G S L++ NP R A V + Sbjct: 9032 TSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDA 9091 Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNK 529 + G H + +SW+++++ Sbjct: 9092 VVGESADFECHVTGTQPIKVSWAKDSR 9118 Score = 124 bits (298), Expect = 2e-26 Identities = 129/507 (25%), Positives = 210/507 (41%), Gaps = 26/507 (5%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E IIE+P +TV P L C G+P + +W+K G + +D+ I + L Sbjct: 7570 EPARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASL 7629 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGDTVVL 127 + + SD G+Y E NS G + ++HV+ ++ F + + + G +VVL Sbjct: 7630 KIPCAEM-SDKGLYSFEVKNSVGKSNC-TVSVHVSDRIVPPSFIRKLKDVNAILGASVVL 7687 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAA 186 EC GS +V W ++G ++ + + L + +D G Y C+A N A Sbjct: 7688 ECRVS-GSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVA 7746 Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 G+ E + A L + P P+ V G S+TF + G P V W + + +P Sbjct: 7747 GSDECS-AVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRE-LVPG 7804 Query: 247 GRVKV-LDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303 + L+D L L V + G+YSC N G+ S + +L V +P + + Sbjct: 7805 ESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLADFS 7864 Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363 VE+G+ T TG P ++ W ++ I S+ + + + + T+L I ++ Sbjct: 7865 VETGSPIVLEATYTGTPPISVSW-IKDEYLI-----SQSERCSITMTEKSTILEILESTI 7918 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423 D C N AG ++V PP + I A C Sbjct: 7919 EDYAQ-YSCLIENEAGQDICEALVSVLE-----PPYFIEPLEHVEAVIGEPATLQCKVDG 7972 Query: 424 TPEPIIAWYFEGEAL--IQNHRRNVTND-GTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480 TPE I+WY E L ++ N+ +LV+ +D SD G Y+C A + G S Sbjct: 7973 TPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSA 8032 Query: 481 ALLVDSPINPNIHFFRAADVSSLPGPP 507 L++ P + DV G P Sbjct: 8033 VLVIKERKLPPFFARKLKDVHETLGFP 8059 Score = 122 bits (293), Expect = 8e-26 Identities = 124/467 (26%), Positives = 186/467 (39%), Gaps = 30/467 (6%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 L C GS +I+W+K + + FL + +D+G Y C ATN Sbjct: 5621 LECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLE-GTDSGTYTCSATNK 5679 Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150 G + H+ V + +E Q +T V G+ + W K+ + L Sbjct: 5680 AG---HNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKEL- 5735 Query: 151 FDGDSRMHLVD--GGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208 G +R D +L + A+ TD+G Y C N GT S ATL + P I P Sbjct: 5736 HSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSK-ATLFVKEPPQFIKKP 5794 Query: 209 EDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN-MPLGRVKVLDD-GSLRLDNVILA 265 V V + G S TF+C++ G P V W + + +D + ++ + Sbjct: 5795 SPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVE 5854 Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325 + G Y CEA N G S S L V +PP+ V V + C TG P + Sbjct: 5855 NSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVT 5914 Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT--DKNDSRNTIVCSAVNYAGSSFV 383 W ++ NR I S KY T D V+V ++ T D +D+ C N GS Sbjct: 5915 W-LKNNREI----RSSKKYTLT---DRVSVFNLHITKCDPSDT-GEYQCIVSNEGGSCSC 5965 Query: 384 RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN-- 441 ++ + + PP N T +KS A F T +P I W + + L ++ Sbjct: 5966 STRVAL-----KEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDN 6020 Query: 442 -HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 + V + TL ++ +D SG YTC A + G LLV P Sbjct: 6021 VYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEP 6067 Score = 122 bits (293), Expect = 8e-26 Identities = 127/492 (25%), Positives = 206/492 (41%), Gaps = 25/492 (5%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 +T E P + P V V T G+P ++W+KG +V +I Sbjct: 7755 LTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDF 7814 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDT 124 + L + ++G Y C TN G+A + T H+ V ++ + S + G Sbjct: 7815 VTELELFEVQP-LESGDYSCLVTNDAGSA---SCTTHLFVKEPATFVKRLADFSVETGSP 7870 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIAR 183 +VLE G+P +V W K+ + + + + ++ I ++ D +Y C+ Sbjct: 7871 IVLEATYT-GTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLIE 7929 Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW-RRSAGGG 242 N AG ++ A + + PY I E V A G T QC+V G P + W + Sbjct: 7930 NEAG-QDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLR 7988 Query: 243 NMPLGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLS 298 + P +++ ++ SL ++ V +D GEYSC+A+NSVGAV++S L + + PP Sbjct: 7989 SAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKERKLPPFFARK 8048 Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358 V+ G F C G + W +G ++ + D T+ V L I Sbjct: 8049 LKDVHETLGFPVAFECRINGSEPLQVSWYKDG---VL---LKDDANLQTSFVHNVATLQI 8102 Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418 TD++ CSA N G++ KL ++ + PP P + L + F Sbjct: 8103 LQTDQSHI-GQYNCSASNPLGTASSSAKLILS--EHEVPPFFDLKPVSVDLALGESGTFK 8159 Query: 419 CTAICTPEPIIAWYFEGEALIQ--NHRRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 C T I W + + N++ V N TL + + K D+G YTC AS+ GK Sbjct: 8160 CHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGK 8219 Query: 476 YVWSGALLVDSP 487 S L V P Sbjct: 8220 DSCSAHLGVQEP 8231 Score = 121 bits (292), Expect = 1e-25 Identities = 125/497 (25%), Positives = 190/497 (38%), Gaps = 29/497 (5%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64 ++T E PY +E+P V + L GG+ I+W+K + S RS+ Sbjct: 5688 HLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDD 5747 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124 L + +D+G Y C+ +N GTA S+ ATL V + + G + Sbjct: 5748 TSTSLELFAAKA-TDSGTYICQLSNDVGTATSK-ATLFVKEPPQFIKKPSPVLVLRNGQS 5805 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIAR 183 EC G+P+ V W +G + + +DG I AR ++G Y C AR Sbjct: 5806 TTFEC-QITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEAR 5864 Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSA 239 N AGT +I LK+ P I + V S V +C V G P +V W R Sbjct: 5865 NDAGTASCSI-ELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIR 5923 Query: 240 GGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298 L RV V +L + +D GEY C N G+ S S + + +PPS Sbjct: 5924 SSKKYTLTDRVSVF---NLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKK 5980 Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358 + + A F T G P ++ W + + D + D V L I Sbjct: 5981 IENTTTVLKSSATFQSTVAGSPPISITWLKDDQI------LDEDDNVYISFVDSVATLQI 6034 Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418 D N C A N +G L V P I+ S K Sbjct: 6035 RSVD-NGHSGRYTCQAKNESGVERCYAFLLV----QEPAQIVEKAKSVDVTE-KDPMTLE 6088 Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGK 475 C TPE + W +G+ ++ + +++ N + ++ + K DSG YT + G Sbjct: 6089 CVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGS 6148 Query: 476 YVWSGAL-LVDSPINPN 491 L ++D I P+ Sbjct: 6149 SSCDAYLRVLDQNIPPS 6165 Score = 121 bits (291), Expect = 1e-25 Identities = 124/492 (25%), Positives = 205/492 (41%), Gaps = 25/492 (5%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 +T E P +++P + V + T G+P + W++G +V +I Sbjct: 6814 LTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDT 6873 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDT 124 + L + + S +G Y C +N+ G A + T + V L+ S S + G + Sbjct: 6874 VAELELFNIDI-SQSGEYTCVVSNNAGQA---SCTTRLFVKEPAAFLKRLSDHSVEPGKS 6929 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIAR 183 ++LE G+ +V WKK+G + + + ++ I ++ + DAG+Y C Sbjct: 6930 IILES-TYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIE 6988 Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW-RRSAGGG 242 N AG R+ A + PY +T E + A G SV+ QC+V G P V W + Sbjct: 6989 NEAG-RDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLR 7047 Query: 243 NMPLGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLS 298 P R ++ +L + V + D GEY+C+AENS+G S+ + + PPS Sbjct: 7048 PTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQ 7107 Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358 + G TC G + W +G ++ + D+ T+ D V L I Sbjct: 7108 LKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDG---VL---LRDDENLQTSFVDNVATLKI 7161 Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418 TD + S CSA N G++ +L T+ + + P P + + A F Sbjct: 7162 LQTDLSHS-GQYSCSASNPLGTASSSARL--TAREPKKSPFFDIKPVSIDVIAGESADFE 7218 Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGK 475 C I W + + + +T N L + + K DSG YTC A++ GK Sbjct: 7219 CHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGK 7278 Query: 476 YVWSGALLVDSP 487 + S L V P Sbjct: 7279 DMCSAQLSVKEP 7290 Score = 117 bits (281), Expect = 2e-24 Identities = 125/490 (25%), Positives = 212/490 (43%), Gaps = 35/490 (7%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAGGLFFLR 70 P +++ D++ + L G+ ++ W+K G +V + I + + L+ Sbjct: 8419 PRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQ 8478 Query: 71 ATHGRVH-SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLE 128 + RV ++AG Y C+ N G ATL +VL +E PES + GDT LE Sbjct: 8479 FS--RVEPANAGKYTCQIKNDAGMQECF-ATL--SVLEPATIVEKPESIKVTTGDTCTLE 8533 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAG 187 C G+PE + W K+G+ L D ++ + L I + +D+G Y +N G Sbjct: 8534 CTVA-GTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVG 8592 Query: 188 TRESAIATLKIH---IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 ++S A+L++ + P ++ +GSSV +C+V G P V W G + Sbjct: 8593 -KDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHE--GNEI 8649 Query: 245 PLGRV--KVLDDGSLRLDNVIL--ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300 GR L D + L +L +D G+Y+C A N G+ S LTV +PPS P+ Sbjct: 8650 SSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPD 8709 Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360 ++V +G FT G P ++ W +G+ ++ PG D+ + ++ D V L + D Sbjct: 8710 PMDVLTGTNVTFTSIVKGTPPFSVSW-FKGSSELV-PG---DRCN-VSLEDSVAELELFD 8763 Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420 D + S C N AG + L + + P ++ ++ + T Sbjct: 8764 VDTSQS-GEYTCIVSNEAGKASCTTHLYI-----KAPAKFVKRLNDYSIEKGKPLILEGT 8817 Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS---DSGTYTCVASSRHGKYV 477 TP + W G + + R N+T + ++ S D+G Y C + GK Sbjct: 8818 FTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDS 8877 Query: 478 WSGALLVDSP 487 S +L+ P Sbjct: 8878 CSAQILILEP 8887 Score = 116 bits (280), Expect = 3e-24 Identities = 114/486 (23%), Positives = 190/486 (39%), Gaps = 22/486 (4%) Query: 10 EAPYIIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68 E P +++ VA+ + L C+ GSP + W++ + ++ + Sbjct: 7289 EPPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVAL 7348 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128 L D+G Y CEA N G A A A F +P + +G V+L+ Sbjct: 7349 LTINEASAE-DSGDYICEAHNGVGDASCSTALTVKAP--PVFTQKPSPVGALKGSDVILQ 7405 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAG 187 C G+P V W K+ + + ++ +L I + +D G Y C A N G Sbjct: 7406 C-EISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVG 7464 Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMP 245 + ++ ++K P + D G +V + V G V+W + G Sbjct: 7465 S-DTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESE 7523 Query: 246 LGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304 R+ +D+ +L+L + ++ G+Y C+ +N G S LTV +P I P + V Sbjct: 7524 NTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEPMTV 7583 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 +GN C TG PE + W +G +S D H + V L I + + Sbjct: 7584 TTGNPFALECVVTGTPELSAKWFKDGRE------LSADSKHHITFINKVASLKIPCAEMS 7637 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424 D + N G S ++V D PP + + + V C + Sbjct: 7638 D-KGLYSFEVKNSVGKS--NCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGS 7694 Query: 425 PEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481 + W+ +G ++ + + N TL L L+ SD+G YTCVA++ G S Sbjct: 7695 APISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAV 7754 Query: 482 LLVDSP 487 L V P Sbjct: 7755 LTVQEP 7760 Score = 115 bits (277), Expect = 7e-24 Identities = 125/481 (25%), Positives = 192/481 (39%), Gaps = 30/481 (6%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E PY ++Q V V+ A+L C+ G+P + WYKG + T + + L Sbjct: 8886 EPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATL 8945 Query: 70 RATHGRVHSDAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128 + +D+G Y C+A NS G + S T+ L F + Q G VV + Sbjct: 8946 VFNQVDI-NDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFD 9004 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAG 187 C GS +V W K+G+ L + + +D L I ++ AG+Y C A N G Sbjct: 9005 C-AISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIG 9063 Query: 188 TRESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGG 241 + S+ + K P+ V A G S F+C V G V W R G Sbjct: 9064 SASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSG 9123 Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLS 298 G + ++ + L + V D G+Y+C A N VG S + L + + PPS Sbjct: 9124 GKYQISYLE--NSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKR 9181 Query: 299 -PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 +V GN + G T+ W N I P + + + VL Sbjct: 9182 LSETVEETEGNSFKLEGRVAGSQPITVAW--YKNNIEIQPTSNCE----ITFKNNTLVLQ 9235 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417 + ND+ C N AGS+ + + + + PP+ + T+ Sbjct: 9236 VRKAGMNDA-GLYTCKVSNDAGSALCTSSIVI--KEPKKPPVFDQHLTPVTVSEGEYVQL 9292 Query: 418 PCTAICTPEPI-IAWYFEGEALIQNHRRNVT-NDGTLV--LKDLDKSDSGTYTCVASSRH 473 C + EPI I W G + + R + + GT V L+D+ K+DSG Y C AS+ Sbjct: 9293 SC-HVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVA 9351 Query: 474 G 474 G Sbjct: 9352 G 9352 Score = 115 bits (276), Expect = 9e-24 Identities = 121/518 (23%), Positives = 203/518 (39%), Gaps = 27/518 (5%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 D ++ + +P L G+P ++ W K G+ V +I L V D Sbjct: 8803 DYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVE-D 8861 Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVLECLPPRGSPEP 138 AG Y C N+ G + + + +L + ++ E + + GD+ L+C G+PE Sbjct: 8862 AGQYNCYIENASG---KDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQC-QLAGTPEI 8917 Query: 139 NVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAG--TRESAIAT 195 V W K L +MH + LV D+G Y C A N+ G + + + Sbjct: 8918 GVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTV 8977 Query: 196 LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDD 254 + + P DV G V F C + G V W + + P + LD+ Sbjct: 8978 QEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDN 9037 Query: 255 -GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLSPNSVNVESGNVA 310 +L + + G+YSC A N +G+ S+S L + + PP ++ V+ G A Sbjct: 9038 TATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGESA 9097 Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370 F C TG + W+ + +R I S KY + + + LT+ DK DS Sbjct: 9098 DFECHVTGTQPIKVSWAKD-SREI----RSGGKYQISYL-ENSAHLTVLKVDKGDS-GQY 9150 Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-I 429 C AVN G +L + + PP T S + + + +PI + Sbjct: 9151 TCYAVNEVGKDSCTAQLNIK--ERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITV 9208 Query: 430 AWYFEGEALIQNHRRNVT-NDGTLVL--KDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486 AWY + +T + TLVL + +D+G YTC S+ G + + ++++ Sbjct: 9209 AWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKE 9268 Query: 487 PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSW 524 P P + V+ G + H + + W Sbjct: 9269 PKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQW 9306 Score = 114 bits (275), Expect = 1e-23 Identities = 126/486 (25%), Positives = 197/486 (40%), Gaps = 40/486 (8%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 V AP I + + VA A C +P+ +W+K G + SI + Sbjct: 4377 VVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKY 4436 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA-VLREEFRLEPESKQSAQGDT 124 + L +V D G Y C+A+N YG+ S ATL V F P+S + G Sbjct: 4437 ISSLEILRTQV-VDCGEYTCKASNEYGSV-SCTATLTVTEAYPPTFLSRPKSLTTFVGKA 4494 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTL-------LFDGDSRMHLVDGGNLVIQDARQTDAGR 177 C G+P W+K+G L + D +++ H+++ NL IQ D G Sbjct: 4495 AKFIC-TVTGTPVIETIWQKDGAALSPSPNWKISDAENK-HILELSNLTIQ-----DRGV 4547 Query: 178 YQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 Y C A N G + A L I KP+ I E V + V +C+V D V W Sbjct: 4548 YSCKASNKFGA-DICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTW-- 4604 Query: 238 SAGGGNMPLGR-VKV-LDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293 S G +P G+ K+ +D +L + L D G Y C A N G+ S S +TV +PP Sbjct: 4605 SKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPP 4664 Query: 294 S-INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352 S + S + G AR C G P + W + N+ +S + Sbjct: 4665 SFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTW-FKNNKE-----LSESNTVRMYFVNS 4718 Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412 +L I D DS + C AVN GS ++ + + PP + Sbjct: 4719 EAILDITDVKVEDS-GSYSCEAVNDVGSDSCSTEIVI-----KEPPSFIKTLEPADIVRG 4772 Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL---DKSDSGTYTCVA 469 + A+ C T I+W+ + + + + + + + +LV ++ + +D G Y CV Sbjct: 4773 TNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVV 4832 Query: 470 SSRHGK 475 ++ GK Sbjct: 4833 ANEVGK 4838 Score = 114 bits (274), Expect = 2e-23 Identities = 125/493 (25%), Positives = 194/493 (39%), Gaps = 37/493 (7%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P P V ++ +L C G+P + WYK + S I + Sbjct: 6442 EPPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSI 6501 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVVL 127 + SD G Y C+A N G+ + + L+E F + S G+ L Sbjct: 6502 HILNVDT-SDIGEYHCKAQNEVGS----DTCVCTVKLKEPPRFVSKLNSLTVVAGEPAEL 6556 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDS-RMHLVDG-GNLVIQDARQTDAGRYQCIARNA 185 + G+ V W K + ++ + ++ R+ V+ L A +AG+Y C +N Sbjct: 6557 QA-SIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKND 6615 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 G E+ +ATL + ++ + G + T +C+V G P V W + G + Sbjct: 6616 GGMEEN-MATLMVLEPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKD---GKLL 6671 Query: 246 LGRVK-----VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINL 297 K SLR+ +V D G Y+ + +N+VG S + + V D PPS Sbjct: 6672 TSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTR 6731 Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 + G C G ++ W E + + S KY T D V L Sbjct: 6732 RLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIV-----SGAKYQ-TTFSDNVCTLQ 6785 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417 +N D +D N C A N AGS R LTV PP + + LP K++ F Sbjct: 6786 LNSLDSSDMGN-YTCVAANVAGSDECRAVLTV----QEPPSFVKEPEPLEVLPGKNV-TF 6839 Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHG 474 TP + W+ L++ R N+ + T L L ++D S SG YTCV S+ G Sbjct: 6840 TSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAG 6899 Query: 475 KYVWSGALLVDSP 487 + + L V P Sbjct: 6900 QASCTTRLFVKEP 6912 Score = 113 bits (272), Expect = 3e-23 Identities = 120/456 (26%), Positives = 178/456 (39%), Gaps = 27/456 (5%) Query: 43 IRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG-TARSRNATL 101 + WY LV SD L + L G Y CEA N G TA S T+ Sbjct: 4318 VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTV 4377 Query: 102 HVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL-FDGDSRMHLV 160 V + + E + A G C + +P W K G+ + D S Sbjct: 4378 -VKRAAPVIKRKIEPLEVALGHLAKFTC-EIQSAPNVRFQWFKAGREIYESDKCSIRSSK 4435 Query: 161 DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH--IKPYLITGPEDVVAQTGSS 218 +L I + D G Y C A N G+ S ATL + P ++ P+ + G + Sbjct: 4436 YISSLEILRTQVVDCGEYTCKASNEYGS-VSCTATLTVTEAYPPTFLSRPKSLTTFVGKA 4494 Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAE 275 F C V G P+ + +W++ G P K+ D + L L N+ + D G YSC+A Sbjct: 4495 AKFICTVTGTPVIETIWQKD-GAALSPSPNWKISDAENKHILELSNLTIQDRGVYSCKAS 4553 Query: 276 NSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII 335 N GA L + D P V C + T+ WS +G + + Sbjct: 4554 NKFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQK--L 4611 Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395 PG K + D + L I DS T VC+A N AGSS +TV Sbjct: 4612 PPG----KDYKICFEDKIATLEIPLAKLKDS-GTYVCTASNEAGSSSCSATVTVR----E 4662 Query: 396 PPPIITN-GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN---VTNDGT 451 PP + PS LP +S A C +P + W+ + L +++ V ++ Sbjct: 4663 PPSFVKKVDPSYLMLPGES-ARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAI 4721 Query: 452 LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 L + D+ DSG+Y+C A + G S +++ P Sbjct: 4722 LDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEP 4757 Score = 108 bits (259), Expect = 1e-21 Identities = 121/490 (24%), Positives = 190/490 (38%), Gaps = 30/490 (6%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P +++ D+ Q TL GS ++ W KG ++ D + + G+ L Sbjct: 4849 EPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVL 4908 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL--EPESKQSAQGDTVVL 127 ++ S G Y C A N G+ S + +++E ++ E Q GD L Sbjct: 4909 IIPDVQI-SFGGKYTCLAENEAGSQTS----VGELIVKEPAKIIERAELIQVTAGDPATL 4963 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAA 186 E G+PE W K+G+ L+ R+ + L A D+G+Y N Sbjct: 4964 E-YTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEV 5022 Query: 187 GTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 G+ E+ L I P+ +V + + C++ G V W + G Sbjct: 5023 GSSSCETTFTVLDRDIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKD-GKEIA 5081 Query: 245 PLGRVKVL---DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301 R ++ SL + V + D G ++C A NSVG+ +SG L V +PPS P S Sbjct: 5082 ASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGS 5141 Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361 +V G+ T G T+ W +GN+ ++ G Y + L + T Sbjct: 5142 KDVLPGSAVCLKSTFQGSTPLTIRW-FKGNKELVSGGSC---YITKEALESSLELYLVKT 5197 Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421 +DS T C N AG L V P + +Q L C Sbjct: 5198 --SDS-GTYTCKVSNVAGGVECSANLFV----KEPATFVEKLEPSQLLKKGDATQLACKV 5250 Query: 422 ICTPEPIIAWYFEGEALIQN--HRRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVW 478 TP I W+ + ++ HR + V + L L D+ DSG Y C A + G Sbjct: 5251 TGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHC 5310 Query: 479 SGALLV-DSP 487 S ++V +SP Sbjct: 5311 SSIVIVKESP 5320 Score = 107 bits (257), Expect = 2e-21 Identities = 113/425 (26%), Positives = 183/425 (43%), Gaps = 37/425 (8%) Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSP 136 S++G Y C+ N G R + + VL +E PE G+ LEC+ G+P Sbjct: 7544 SNSGKYICQIKNDAGM---RECSAVLTVLEPARIIEKPEPMTVTTGNPFALECVVT-GTP 7599 Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195 E + W K+G+ L D + ++ +L I A +D G Y +N+ G T Sbjct: 7600 ELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSN---CT 7656 Query: 196 LKIHIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250 + +H+ P I +DV A G+SV +CRV G V W + GN + K Sbjct: 7657 VSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQD---GNEIVSGPK 7713 Query: 251 VLDDGS-----LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305 S L L + +D G Y+C A N G+ S LTV +PPS +P+SV V Sbjct: 7714 CQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVL 7773 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365 G FT G P + W +G+R ++ PG S + ++ D VT L + + + Sbjct: 7774 PGMSLTFTSVIRGTPPFKVKW-FKGSRELV-PGESCN----ISLEDFVTELELFEVQPLE 7827 Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425 S C N AGS+ L V + P ++ ++ S V T TP Sbjct: 7828 S-GDYSCLVTNDAGSASCTTHLFV-----KEPATFVKRLADFSVETGSPIVLEATYTGTP 7881 Query: 426 EPIIAWYFEGEALIQNHRRNVT-NDGTLVLKDLDKS--DSGTYTCVASSRHGKYVWSGAL 482 ++W + + Q+ R ++T + + +L+ L+ + D Y+C+ + G+ + + Sbjct: 7882 PISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALV 7941 Query: 483 LVDSP 487 V P Sbjct: 7942 SVLEP 7946 Score = 101 bits (243), Expect = 9e-20 Identities = 121/511 (23%), Positives = 186/511 (36%), Gaps = 32/511 (6%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 L C+ GS ++ W+ +VS + + L+ + SD G Y C A N Sbjct: 6746 LECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQL-NSLDSSDMGNYTCVAANV 6804 Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150 G+ R A L V F EPE + G V + RG+P V W + + L+ Sbjct: 6805 AGSDECR-AVLTVQE-PPSFVKEPEPLEVLPGKNVTFTSVI-RGTPPFKVNWFRGARELV 6861 Query: 151 FDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209 ++ D L + + + +G Y C+ N AG + S L + + Sbjct: 6862 KGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAG-QASCTTRLFVKEPAAFLKRLS 6920 Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR----VKVLDDGSLRLDNVILA 265 D + G S+ + G V W++ G N+ V L + N Sbjct: 6921 DHSVEPGKSIILESTYTGTLPISVTWKKD--GFNITTSEKCNIVTTEKTCILEILNSTKR 6978 Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325 D G+YSCE EN G ++ +PP + G+ C G PE T+ Sbjct: 6979 DAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVS 7038 Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385 W +G+ T + P Y + V L N + NDS C A N G++ Sbjct: 7039 W-YKGD-TKLRPTPEYRTYFT----NNVATLVFNKVNINDS-GEYTCKAENSIGTA--SS 7089 Query: 386 KLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT---PEPI-IAWYFEGEALIQN 441 K + + PP + Q I+ P T C PI + WY +G L + Sbjct: 7090 KTVFRIQERQLPPSF----ARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDD 7145 Query: 442 HRRN---VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAA 498 V N TL + D S SG Y+C AS+ G S L P + Sbjct: 7146 ENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIKPV 7205 Query: 499 DVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529 + + G H + ++WS++NK Sbjct: 7206 SIDVIAGESADFECHVTGAQPMRITWSKDNK 7236 Score = 99.1 bits (236), Expect = 6e-19 Identities = 125/504 (24%), Positives = 195/504 (38%), Gaps = 45/504 (8%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS--DTHRSILPAGGLFFL 69 P Q DV P +C GS ++ WYK G + + S L + Sbjct: 8984 PSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNI 9043 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEF---RLEPESKQSAQGDTVV 126 T S AG Y C ATN G+A S + F RL P + G++ Sbjct: 9044 FKTD---RSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVD--AVVGESAD 9098 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRM-HLVDGGNLVIQDARQTDAGRYQCIARNA 185 EC G+ V W K+ + + G ++ +L + +L + + D+G+Y C A N Sbjct: 9099 FEC-HVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNE 9157 Query: 186 AGTRESAIATLKIH---IKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGG 241 G ++S A L I I P + V +T G+S + RV G V W ++ Sbjct: 9158 VG-KDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKN-NI 9215 Query: 242 GNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP---PSI 295 P ++ + L++ + D G Y+C+ N G+ + + + +P P Sbjct: 9216 EIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVF 9275 Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355 + V V G + +C G + W G I P D+ + + G V Sbjct: 9276 DQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGRE--IKPS---DRC-SFSFASGTAV 9329 Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP----------IITNGPS 405 L + D K DS + VC A N AGS + K+T+ P + P Sbjct: 9330 LELRDVAKADSGD-YVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQ 9388 Query: 406 NQTLPIKSMAVFPCTAICTPEPIIAWYF-EGEALIQNHRRNVTNDGT---LVLKDLDKSD 461 + + K+ A F P P + W + L Q R + G L ++D K+D Sbjct: 9389 SIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTD 9448 Query: 462 SGTYTCVASSRHGKYVWSGALLVD 485 SG Y CVA + HG+ + L VD Sbjct: 9449 SGLYRCVAFNEHGEIESNVNLQVD 9472 Score = 98.7 bits (235), Expect = 8e-19 Identities = 121/527 (22%), Positives = 194/527 (36%), Gaps = 26/527 (4%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I + DV L CR GS ++ W++ G +VS + + L Sbjct: 7668 PSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNL 7727 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131 + SD G+Y C A N G+ +A L V F P+S + G ++ + Sbjct: 7728 SLLEP-SDTGIYTCVAANVAGSDEC-SAVLTVQE-PPSFEQTPDSVEVLPGMSLTFTSVI 7784 Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRE 190 RG+P V W K + L+ + L D L + + + ++G Y C+ N AG Sbjct: 7785 -RGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAG--- 7840 Query: 191 SAIATLKIHIKP--YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248 SA T + +K + D +TGS + + G P V W + + Sbjct: 7841 SASCTTHLFVKEPATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERC 7900 Query: 249 VKVLDDGSLRLDNV--ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306 + + S L+ + + D +YSC EN G ++V +PP V Sbjct: 7901 SITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSVLEPPYFIEPLEHVEAVI 7960 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 G A C G PE + W E + P + + V L IN D +D Sbjct: 7961 GEPATLQCKVDGTPEIRISWYKEHTKLRSAPA------YKMQFKNNVASLVINKVDHSDV 8014 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426 C A N G+ V + + + PP + + F C I E Sbjct: 8015 -GEYSCKADNSVGA--VASSAVLVIKERKLPPFFARKLKDVHETLGFPVAFECR-INGSE 8070 Query: 427 PI-IAWYFEGEALIQNHRRN---VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482 P+ ++WY +G L + V N TL + D+S G Y C AS+ G S L Sbjct: 8071 PLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKL 8130 Query: 483 LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529 ++ P + V G H + ++W+++N+ Sbjct: 8131 ILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNR 8177 Score = 96.3 bits (229), Expect = 4e-18 Identities = 107/488 (21%), Positives = 186/488 (38%), Gaps = 27/488 (5%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P I++ + T AT GSP +I W K ++ D + I + L Sbjct: 5973 EPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVATL 6032 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS--AQGDTVVL 127 + + +G Y C+A N G R L ++E ++ ++K + D + L Sbjct: 6033 QI-RSVDNGHSGRYTCQAKNESGVERCYAFLL----VQEPAQIVEKAKSVDVTEKDPMTL 6087 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAA 186 EC+ G+PE V W K+G+ ++ M + + IQ + D+G+Y N Sbjct: 6088 ECVVA-GTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDF 6146 Query: 187 GTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 G+ ++ + L +I P + GSS+ +C+V G W + + Sbjct: 6147 GSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEIST 6206 Query: 245 PLGRVKVLDDGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302 V + S+ L+ N+ L D Y+C+ N G + SG LTV +PPS + P Sbjct: 6207 SAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQ 6266 Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362 + F G P + W + + P +T+ + +V D Sbjct: 6267 QAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSV----DAS 6322 Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422 K C N GS L VT PP + +++ + + C Sbjct: 6323 KT---GQYTCHVTNDVGSDSCTTMLLVT----EPPKFVKKLEASKIVKAGDSSRLECKIA 6375 Query: 423 CTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479 +PE + W+ L + + +T + + + +L DSG + C A + G S Sbjct: 6376 GSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCS 6435 Query: 480 GALLVDSP 487 ++V P Sbjct: 6436 TKVIVKEP 6443 Score = 95.1 bits (226), Expect = 1e-17 Identities = 125/526 (23%), Positives = 204/526 (38%), Gaps = 32/526 (6%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFF 68 E P + + +TV +PA L G+ ++W K V+ ++ I + Sbjct: 6535 EPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVAT 6594 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDTVVL 127 L+ ++AG Y C+ N G + ATL VL +E + G+T L Sbjct: 6595 LQFAKAEP-ANAGKYICQIKNDGGMEENM-ATL--MVLEPAVIVEKAGPMTVTVGETCTL 6650 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAA 186 EC G+PE +V W K+G+ L + + +L I + DAG Y +N Sbjct: 6651 EC-KVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNV 6709 Query: 187 GTRESAIATLKIH---IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 G + S A + + + P ++ G+S +C+V G V W Sbjct: 6710 G-KSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIV 6768 Query: 244 MPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301 D +L+L+++ +D G Y+C A N G+ LTV +PPS P Sbjct: 6769 SGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPEP 6828 Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361 + V G FT G P + W G R ++ G + Y D V L + + Sbjct: 6829 LEVLPGKNVTFTSVIRGTPPFKVNW-FRGARELV-KGDRCNIYFE----DTVAELELFNI 6882 Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421 D + S C N AG + +L V P + + P KS+ + T Sbjct: 6883 DISQS-GEYTCVVSNNAGQASCTTRLFV----KEPAAFLKRLSDHSVEPGKSI-ILESTY 6936 Query: 422 ICTPEPIIAWYFEGEALIQNHRRN-VTNDGTLVLKDLD--KSDSGTYTCVASSRHGKYVW 478 T + W +G + + + N VT + T +L+ L+ K D+G Y+C + G+ V Sbjct: 6937 TGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDV- 6995 Query: 479 SGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSW 524 GAL+ S + P + + G +T+SW Sbjct: 6996 CGALV--STLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSW 7039 Score = 94.7 bits (225), Expect = 1e-17 Identities = 113/472 (23%), Positives = 178/472 (37%), Gaps = 24/472 (5%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 + P+ I++ V A ++ L C+ + W K G + I + L Sbjct: 4569 DKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATL 4628 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 ++ D+G Y C A+N G++ S +AT+ V + S G++ L C Sbjct: 4629 EIPLAKL-KDSGTYVCTASNEAGSS-SCSATVTVREPPSFVKKVDPSYLMLPGESARLHC 4686 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGT 188 +GSP V W KN + L RM+ V+ ++ I D + D+G Y C A N G+ Sbjct: 4687 -KLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGS 4745 Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248 +S + I P I E G++ QC V G ++ W + + Sbjct: 4746 -DSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSK-K 4803 Query: 249 VKVLDDGSL---RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305 ++ SL + + AD GEY C N VG + +PP+ + + Sbjct: 4804 YRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKEPPTFVKKVDDLIAL 4863 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365 G G ++ W ++G I G + + +GV VL I D + Sbjct: 4864 GGQTVTLQAAVRGSEPISVTW-MKGQEVIREDGKIKMSFS-----NGVAVLIIPDVQISF 4917 Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425 C A N AGS G+L V P II Q + A T TP Sbjct: 4918 G-GKYTCLAENEAGSQTSVGELIV----KEPAKIIERAELIQ-VTAGDPATLEYTVAGTP 4971 Query: 426 EPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHG 474 E WY +G L+ + + ++ N L + DSG YT S+ G Sbjct: 4972 ELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVG 5023 Score = 94.3 bits (224), Expect = 2e-17 Identities = 113/465 (24%), Positives = 176/465 (37%), Gaps = 26/465 (5%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P + +P V L GS IRW+KG +VS I L Sbjct: 5131 EPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSL 5190 Query: 70 RATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128 + SD+G Y C+ +N G S N + E +LEP S+ +GD L Sbjct: 5191 ELYLVKT-SDSGTYTCKVSNVAGGVECSANLFVKEPATFVE-KLEP-SQLLKKGDATQLA 5247 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAG 187 C G+P + W N + + RM V+ ++ + D D+G Y C A+N AG Sbjct: 5248 C-KVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAG 5306 Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247 + + + + PY + + V V G P ++ W + Sbjct: 5307 SDHCSSIVI-VKESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRK 5365 Query: 248 RVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305 + D SL++ + AD GEY C N VG+ S +T+ +PPS S + Sbjct: 5366 YKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIESTSSL 5425 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD-KN 364 G A F T G T+ W + + ++ D + V L ++ + K+ Sbjct: 5426 RGGTAAFQATLKGSLPITVTWLKDSDE------ITEDDNIRMTFENNVASLYLSGIEVKH 5479 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424 D + VC A N AG L+V + P IT + + A T Sbjct: 5480 DGK--YVCQAKNDAGIQRCSALLSV-----KEPATITEEAVSIDVTQGDPATLQVKFSGT 5532 Query: 425 PEPIIAWYFEGEALIQNHRRNVT-NDGTLVLK--DLDKSDSGTYT 466 E W+ +G+ L + ++ D +LK +K DSG YT Sbjct: 5533 KEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYT 5577 Score = 94.3 bits (224), Expect = 2e-17 Identities = 116/490 (23%), Positives = 179/490 (36%), Gaps = 23/490 (4%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 VT E P I++ + R A GS + W K + D + + Sbjct: 5407 VTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENN 5466 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 + L + V D G Y C+A N G R +A L V E S QGD Sbjct: 5467 VASLYLSGIEVKHD-GKYVCQAKNDAGIQRC-SALLSVKE-PATITEEAVSIDVTQGDPA 5523 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARN 184 L+ + G+ E W K+GQ L ++ + D +++ I + D+G Y +N Sbjct: 5524 TLQ-VKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQN 5582 Query: 185 AAGTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242 G ++ I L + I P + + + GS + +C V G + W + Sbjct: 5583 DVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEI 5642 Query: 243 NMPLGRVKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300 + D + L + + D G Y+C A N G SG+LTV +PP P Sbjct: 5643 SASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQ 5702 Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360 S +V + G T+ W + + G +R + D T L + Sbjct: 5703 SQDVNPNTRVQLKALVGGTAPMTIKWFKDNKE--LHSGAARSVWKD----DTSTSLELFA 5756 Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420 DS T +C N G++ + L V PP I L F C Sbjct: 5757 AKATDS-GTYICQLSNDVGTATSKATLFV----KEPPQFIKKPSPVLVLRNGQSTTFECQ 5811 Query: 421 AICTPEPIIAWYFEGEAL--IQNHRRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477 TP+ ++WY +G + IQ H + + T + +SGTY C A + G Sbjct: 5812 ITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTAS 5871 Query: 478 WSGALLVDSP 487 S L V P Sbjct: 5872 CSIELKVKEP 5881 Score = 80.6 bits (190), Expect = 2e-13 Identities = 109/520 (20%), Positives = 209/520 (40%), Gaps = 44/520 (8%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 + C+ GS + +W+K G + + ++ L + + A Y C+ +N Sbjct: 6183 MECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTAN-YTCKVSNV 6241 Query: 91 YGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148 G +A + ++E F ++P +Q+ TV + + +G+P + W K+ Sbjct: 6242 AGD----DACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAIL-KGTPPFKIKWFKDDVE 6296 Query: 149 LLFDGDSRMHLVDGG----NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL 204 L+ G ++G NL DA +T G+Y C N G+ +S L + P Sbjct: 6297 LV-SGPKCFIGLEGSTSFLNLYSVDASKT--GQYTCHVTNDVGS-DSCTTMLLVTEPPKF 6352 Query: 205 ITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---RVKVLDDGS-LRL 259 + E + + G S +C++ G P V+W R+ +P R+ +D + +++ Sbjct: 6353 VKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEH--ELPASDKYRMTFIDSVAVIQM 6410 Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGR 319 +N+ D G++ CEA+N G+ S S + V +PP + P V C +G Sbjct: 6411 NNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLECELSGT 6470 Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379 P + W + + + K + + +L ++ +D + C A N G Sbjct: 6471 PPFEVVWYKDKRQ---LRSSKKYKIASKNFHTSIHILNVDTSDIGEYH----CKAQNEVG 6523 Query: 380 SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI 439 S V + + PP + ++ T+ A + + W E E +I Sbjct: 6524 SD-----TCVCTVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVI 6578 Query: 440 ---QNHRRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFF 495 +N R V N TL + +++G Y C + G L+V + P + Sbjct: 6579 RESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMEENMATLMV---LEPAVIVE 6635 Query: 496 RAADVSSLPGPPTKPITHNVTDT-SVTLSWSQNNKIGSSS 534 +A ++ G T + V T +++ W ++ K+ +SS Sbjct: 6636 KAGPMTVTVG-ETCTLECKVAGTPELSVEWYKDGKLLTSS 6674 Score = 78.2 bits (184), Expect = 1e-12 Identities = 111/491 (22%), Positives = 197/491 (40%), Gaps = 48/491 (9%) Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193 G P P V W N +TL + + ++VI++ +++ G Y +A+N AG R+ I Sbjct: 17477 GKPPPTVTWNMNERTLPQEATIETTAISS-SMVIKNCQRSHQGVYSLLAKNEAGERKKTI 17535 Query: 194 ATLKIHIKPYLITGP---EDVVAQTGSSVTFQCRV-GGDPLPDVLWRRSAGGGNMPLGRV 249 + + P + P ++ ++ F GG P+ + + + Sbjct: 17536 IVDVLDV-PGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVT 17594 Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGA---VSASGYLTVYDPPSINLSPNSVNVES 306 + + + +I + AENS+G V S L + +P ++ P + V+ Sbjct: 17595 YTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKE 17654 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT-VLTINDTDKND 365 V + T T T P S N + + +K+H + ++ T+ + D Sbjct: 17655 --VTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGD 17712 Query: 366 SRNTIVCSAVNYAGS---SFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422 + V SAVN G SF +T D+ PP + + T+ + Sbjct: 17713 TYEYRV-SAVNIVGQGKPSFCTKPITC-KDELAPPTLHLDFRDKLTIRVGEAFALTGRYS 17770 Query: 423 CTPEPIIAWYFEGEALIQNHRRNV-TNDGTLVLKDLD--KSDSGTYTCVASSRHGKYVWS 479 P+P ++W+ + ++++ R ++ T TL L+ + +SDSG Y V + G Sbjct: 17771 GKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSR--K 17828 Query: 480 GALLVDSPINPNIHFFRAADVSSLPGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSILGY 538 G F +V PGPP P++ + VT + +SW G S I Y Sbjct: 17829 G--------------FCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNY 17874 Query: 539 QVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598 +E +E G + W+ + +T V L+ G Y+F + EN +G+S P Sbjct: 17875 IIE--KKEV--GKDV------WMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDP 17924 Query: 599 SPVSDSVTVGD 609 VSDS+ D Sbjct: 17925 L-VSDSMKAKD 17934 Score = 75.8 bits (178), Expect = 7e-12 Identities = 162/702 (23%), Positives = 278/702 (39%), Gaps = 75/702 (10%) Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGT 188 +P +G P P + W K L + D + ++ + DAG+Y N+ G Sbjct: 20642 VPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGK 20701 Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV--GGDPLPD-VLWRRSAGGGNMP 245 +E I + + +++ + VT++ + GG P+ + V+ +R A + Sbjct: 20702 KEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWS 20761 Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV-NV 304 + S R+ N+ + AEN G + G D + +P V ++ Sbjct: 20762 TVTTEC-SKTSFRVANLEEGKSYFFRVFAENEYG-IGDPG--ETRDAVKASQTPGPVVDL 20817 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP-GMSRDKYHATAVFDGVTVLTINDTDK 363 + +V++ +C+ G +P S G+R I + ++ V ++ L + D Sbjct: 20818 KVRSVSKSSCSI-GWKKPH---SDGGSRIIGYVVDFLTEENKWQRVMKSLS-LQYSAKDL 20872 Query: 364 NDSRN-TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422 + + T SA N G V DD P + G + K + F Sbjct: 20873 TEGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIP 20932 Query: 423 CT--PEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGKYV 477 P P ++W + L + R +V + TL++ D KSD+G YT + G Sbjct: 20933 IKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTK- 20991 Query: 478 WSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSIL 536 G + + V PG PT PI + VT ++TL W+ G S I Sbjct: 20992 -EGTISIK--------------VVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEIT 21036 Query: 537 GYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596 Y +E R+++ NN WV A V +T + V L G+ Y F V EN +G+ Sbjct: 21037 NYILE--KRDSV--NNK------WVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGV- 21085 Query: 597 GPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEIL 656 G S+ + + V ++ N + H + + T D K K + Sbjct: 21086 GEGLKSEPIVARHPFD-------VPDAPPPPNIVDVRH--DSVSLTWTDPK--KTGGSPI 21134 Query: 657 NFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEG 716 Y+LE F+ +++ + KT + D F++T L + +YEF ++ G Sbjct: 21135 TGYHLE-----FKERNSLLWKRANKTPIRMRD---FKVTGLTEGLEYEFRVMAINLAGVG 21186 Query: 717 KPS-NSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLD 775 KPS S LD P PP E+ + +V L W+ P+ +TGY +V D Sbjct: 21187 KPSLPSEPVVALD--PIDPPGKPEVINITRNSVTLIWTEPKYD-GGHKLTGY--IVEKRD 21241 Query: 776 VPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817 +P+ M A + V + + +T+L G Y +I A+ G Sbjct: 21242 LPSKSWMKANHVNVPEC-AFTVTDLVEGGKYEFRIRAKNTAG 21282 Score = 72.5 bits (170), Expect = 6e-11 Identities = 67/228 (29%), Positives = 106/228 (46%), Gaps = 10/228 (4%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 +TSGEAP I ++ DVT + A L+C+ G P P I+WY+ G ++ + + + + G Sbjct: 31454 LTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELI-QSRKYKMSSDG 31512 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV--LREEFRLEPESKQSAQGD 123 D GVY C ATN G + + L A + L+ E A G Sbjct: 31513 RTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLK-EKYYGAVGS 31571 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM--HLVDGGNLVIQDA-RQTDAGRYQC 180 T+ L + G P P + W +GQ LL + ++ + +LV+++ R+T AG+Y+ Sbjct: 31572 TLRLHVM-YIGRPVPAMTW-FHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKV 31629 Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228 N GT + AI ++I KP TGP + A +S + D Sbjct: 31630 QLSNVFGTVD-AILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPAD 31676 Score = 72.1 bits (169), Expect = 8e-11 Identities = 114/458 (24%), Positives = 180/458 (39%), Gaps = 67/458 (14%) Query: 177 RYQCIARNAAGTRESAIATLKIHIK-PY---LITGPEDVVAQTGSSVTFQ-----CRVGG 227 +++ IA+N G E++ A+ + K P+ G ++++ + SVT Q C G Sbjct: 31328 QFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGK 31387 Query: 228 DPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG-------A 280 + L + R +G + + D + ++ A E E+ AEN G A Sbjct: 31388 EILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTA 31447 Query: 281 VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340 +S LT + P I V + G A+ +C GRP P + W G I S Sbjct: 31448 MSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELI----QS 31503 Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP--P 398 R KY ++ DG T T++ + C A N G KL + + P P Sbjct: 31504 R-KYKMSS--DGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYP 31560 Query: 399 IITN--GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT----- 451 + G TL + M I P P + W F G+ L+QN N+T + T Sbjct: 31561 LKEKYYGAVGSTLRLHVM------YIGRPVPAMTW-FHGQKLLQN-SENITIENTEHYTH 31612 Query: 452 LVLKDLD-KSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKP 510 LV+K++ K+ +G Y S+ G VD+ ++ ++ P PT P Sbjct: 31613 LVMKNVQRKTHAGKYKVQLSNVFG--------TVDAILD--------VEIQDKPDKPTGP 31656 Query: 511 IT-HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQ 569 I + S +SW G S I Y VE E G W +++ + Sbjct: 31657 IVIEALLKNSAVISWKPPADDGGSWITNYVVE--KCEAKEGAE-------WQLVSSAISV 31707 Query: 570 THYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607 T + +L Y F V +N+ G+S P VS V + Sbjct: 31708 TTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVII 31745 Score = 68.9 bits (161), Expect = 8e-10 Identities = 47/180 (26%), Positives = 90/180 (50%), Gaps = 11/180 (6%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVI 167 F L+P S + +G T + L G P P +W +GQ ++ D ++ + + G +L+I Sbjct: 1459 FVLKPVSFKCLEGQTARFD-LKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLII 1517 Query: 168 QDARQTDAGRYQCIARNAAGTRE-SAIATLKI---HIKPYLITGPEDVVAQTGSSVTFQC 223 A +D+G + +A+N AG S I T++ +KP + ++V + GS + + Sbjct: 1518 VPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSQLEMKV 1577 Query: 224 RVGGDPLPDVLWRRSAG---GGNMPLGRVK-VLDDGSLRLDNVILADEGEYSCEAENSVG 279 R G+P PD++W +++ P R++ + +L++D+ + D Y+ A N G Sbjct: 1578 RATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAG 1637 Score = 68.1 bits (159), Expect = 1e-09 Identities = 102/414 (24%), Positives = 171/414 (41%), Gaps = 38/414 (9%) Query: 92 GTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLF 151 G A S ATL+V EFR + + + + EC P+ V W K+ Q L Sbjct: 3043 GKATS-TATLYVEARHIEFRKHIKDIKVLEKKRAMFEC--EVSEPDITVQWMKDDQELQI 3099 Query: 152 DGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED 210 ++ + L+I R +DAG+Y +A T + + + I+ I Sbjct: 3100 TDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRS--IKKEVQ 3157 Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLR---LDNVILAD 266 V+ + + V F+ V D + D W + N + R K + + + + +D Sbjct: 3158 VIEKQRAVVEFE--VNEDDV-DAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSD 3214 Query: 267 EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326 GEY+ A + +V+ Y+ +PP + V V+SG ARF +GRP+P + W Sbjct: 3215 AGEYTFVAGRNRSSVTL--YVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISW 3272 Query: 327 SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386 E ++ G H + T+L I ++ + T C A N G + Sbjct: 3273 YKE--EQLLSTGFKCKFLHDGQEY---TLLLIEAFPEDAAVYT--CEAKNDYGVATTSAS 3325 Query: 387 LT-----VTSDDDR----PPPIITNGPSNQTLPIKSM-AVFPCTAICTPEPIIAWYFEGE 436 L+ V S D PP IIT P T+ + A F C T + ++WY + + Sbjct: 3326 LSVEVPEVVSPDQEMPVYPPAIIT--PLQDTVTSEGQPARFQCRVSGT-DLKVSWYSKDK 3382 Query: 437 ALIQNHRRNVTN-DGT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 + + +T + T L + + D GTYT VAS+ G+ + L +++P Sbjct: 3383 KIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAP 3436 Score = 68.1 bits (159), Expect = 1e-09 Identities = 83/320 (25%), Positives = 128/320 (40%), Gaps = 37/320 (11%) Query: 292 PPSINLSPNSVN---VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348 PPS+ L + V++G RF G P PT W+ +G+ + D+++ Sbjct: 18434 PPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSE------IKTDEHYTVE 18487 Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN-- 406 + +VLTI + + D+ + + N AGS V LTV D P P GP N Sbjct: 18488 TDNFSSVLTIKNCLRRDTGEYQI-TVSNAAGSKTVAVHLTVL---DVPGP--PTGPINIL 18541 Query: 407 QTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYT 466 P + P+I + E + ++ V++ + + G Sbjct: 18542 DVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGC-E 18600 Query: 467 CVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQ 526 V R + G L +P F S P PP KP+ ++T+ + T+SW+ Sbjct: 18601 YVFRVRAENKIGVGPPLDSTPTVAKHKF-------SPPSPPGKPVVTDITENAATVSWTL 18653 Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMF 585 G S I GY +E R ++G WV + + + + V L G TY F Sbjct: 18654 PKSDGGSPITGYYME---RREVTGK--------WVRVNKTPIADLKFRVTGLYEGNTYEF 18702 Query: 586 IVRTENSHGLSGPSPVSDSV 605 V EN GLS PSP SD + Sbjct: 18703 RVFAENLAGLSKPSPSSDPI 18722 Score = 68.1 bits (159), Expect = 1e-09 Identities = 156/706 (22%), Positives = 269/706 (38%), Gaps = 83/706 (11%) Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189 +P +G P P V W K+ L + + L+I + + D G++ N AG + Sbjct: 21725 VPIKGRPAPEVTWTKDNINLKNRANIE-NTESFTLLIIPECNRYDTGKFVMTIENPAGKK 21783 Query: 190 ESAIATLKIHIK-PYLITGPEDVVAQTGSSVTFQCRV----GGDPLPD-VLWRRSAGGGN 243 + + P L P D+ T SVT + GG + + ++ +R A + Sbjct: 21784 SGFVNVRVLDTPGPVLNLRPTDI---TKDSVTLHWDLPLIDGGSRITNYIVEKREATRKS 21840 Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303 K + ++ + E + AEN G + P+S+N Sbjct: 21841 YSTATTKC-HKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLN 21899 Query: 304 VESGNVARFTCT-ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362 + ++ + T + A +P+ + G I D++ G+ + N T+ Sbjct: 21900 IM--DITKSTVSLAWPKPKHDGGSKITGY-VIEAQRKGSDQWTHITTVKGLECVVRNLTE 21956 Query: 363 KNDSRNTIVCSAVNYAGSSFVR-GKLTVTSDDDRPPPIITNGPSNQTLPIKS--MAVFPC 419 + T AVN AG S R + + + P + G + + K+ Sbjct: 21957 GEEY--TFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEI 22014 Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLD---KSDSGTYTCVASSRHGKY 476 + P+P + W + L Q R N T + +++ +SDSG Y A + G+ Sbjct: 22015 PVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGE- 22073 Query: 477 VWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSI 535 V I +H +PGPPT PI + V+ VT SW G I Sbjct: 22074 -------VGDVITIQVH--------DIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPI 22118 Query: 536 LGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGL 595 Y VE+ R+T +S WV +A V +T Y L G+ Y F V+ +N +G+ Sbjct: 22119 SNYVVEM--RQT--------DSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGV 22168 Query: 596 SGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEI 655 GP S + +N ++ G + + + A DS TI + Sbjct: 22169 -GPGITSACIV----ANYPFKVPGPPGTPQ-------------VTAVTKDSMTISWHEPL 22210 Query: 656 LN-FYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKF 714 + + G + + + I + K ++ N F+ + L YEF +I Sbjct: 22211 SDGGSPILGYHVERKERNGILWQTVSKALVPGNI---FKSSGLTDGIAYEFRVIAENMAG 22267 Query: 715 EGKPSN-SRVAQTLDDV-PDGPPINIEMFILNTTTVHLKWSPPELQLQNGI-ITGYNVVV 771 + KPS S LD + P G P+ + + TV LKW+ PE G IT Y +V Sbjct: 22268 KSKPSKPSEPMLALDPIDPPGKPVPLN---ITRHTVTLKWAKPE--YTGGFKITSY--IV 22320 Query: 772 NWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817 D+P + + A + + + ++ LT +Y ++ A+ G Sbjct: 22321 EKRDLPNGRWLKANFSNILE-NEFTVSGLTEDAAYEFRVIAKNAAG 22365 Score = 66.9 bits (156), Expect = 3e-09 Identities = 77/272 (28%), Positives = 113/272 (41%), Gaps = 32/272 (11%) Query: 45 WYKGGVLV---VSDTHRSILPAG-GLFFLRATHGRVHSDAGVY-WCEATNSYGTARSRNA 99 WYK G+ + V + H+ ++ F+ T SDAG Y + N NA Sbjct: 3179 WYKDGIEINFQVQERHKYVVERRIHRMFISETR---QSDAGEYTFVAGRNRSSVTLYVNA 3235 Query: 100 TLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL 159 VL+E L+P + QS + C G P+P + W K Q LL G L Sbjct: 3236 PEPPQVLQE---LQPVTVQSGKPARF---CAVISGRPQPKISWYKEEQ-LLSTGFKCKFL 3288 Query: 160 VDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK-------------PYL 204 DG L++ +A DA Y C A+N G ++ A+L + + P + Sbjct: 3289 HDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTS-ASLSVEVPEVVSPDQEMPVYPPAI 3347 Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG-SLRLDNVI 263 IT +D V G FQCRV G L + + R+ +D L + Sbjct: 3348 ITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAY 3407 Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295 DEG Y+ A N+VG VS++ L++ P SI Sbjct: 3408 PEDEGTYTFVASNAVGQVSSTANLSLEAPESI 3439 Score = 66.5 bits (155), Expect = 4e-09 Identities = 83/325 (25%), Positives = 135/325 (41%), Gaps = 39/325 (12%) Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556 A D P PP P ++ T +SV+LSW + G S I+GY VEV + +N R Sbjct: 20509 ARDPQYPPAPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEV---KRADSDNWVRC 20565 Query: 557 SRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWE 616 + + + + +T + V L+ Y F V N G S PS V D D L Sbjct: 20566 N-----LPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKD---ILIP 20617 Query: 617 GTGVSNSTEYRNNILTDHIVELIEATPIDSK-TIKLMWEILNFYYLEGLFIYFRPLDNIT 675 G ++ + R ++ V + P+ + K+ W +P N+ Sbjct: 20618 PEGELDA-DLRKTLILRAGVTMRLYVPVKGRPPPKITWS--------------KP--NVN 20660 Query: 676 IEYEMKTILHSNDVSGF-EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGP 734 + + + S D F ++ KY ++ L + GK + V + LD GP Sbjct: 20661 LRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILT--LENSCGKKEYTIVVKVLD--TPGP 20716 Query: 735 PINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATS 794 P+N+ + ++ + ++ W PP + + II N VV D A + + TT TS Sbjct: 20717 PVNVTVKEISKDSAYVTWEPPIIDGGSPII---NYVVQKRD--AERKSWSTVTTECSKTS 20771 Query: 795 LIMTNLTSGVSYSVQIAAETIIGLG 819 + NL G SY ++ AE G+G Sbjct: 20772 FRVANLEEGKSYFFRVFAENEYGIG 20796 Score = 64.1 bits (149), Expect = 2e-08 Identities = 80/315 (25%), Positives = 132/315 (41%), Gaps = 36/315 (11%) Query: 504 PGPPTKPIT-HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562 PGPPT P+ ++T+ SVTL W G S + Y + RET ++ W Sbjct: 27497 PGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYIL--LKRET--------STAVWTE 27546 Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSN 622 ++ V +T V L G Y F ++ EN G+S S VTV L T Sbjct: 27547 VSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHID-SACVTV-----KLPYTTPGPP 27600 Query: 623 STEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKT 682 ST + N+ T + + P+ + ++ Y+LE + ++I + K Sbjct: 27601 STPWVTNV-TRESITVGWHEPVSNGGSAVVG-----YHLE-----MKDRNSILWQKANKL 27649 Query: 683 ILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFI 742 ++ + + F++T++ YEF + GKPS+ D + PP N+ + Sbjct: 27650 VIRT---THFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACE-PPRNVRITD 27705 Query: 743 LNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTS 802 ++ +V L W P ITGY +V D+P + A T V + T I++ LT Sbjct: 27706 ISKNSVSLSWQQPAFD-GGSKITGY--IVERRDLPDGRWTKASFTNVTE-TQFIISGLTQ 27761 Query: 803 GVSYSVQIAAETIIG 817 Y ++ A +G Sbjct: 27762 NSQYEFRVFARNAVG 27776 Score = 64.1 bits (149), Expect = 2e-08 Identities = 41/123 (33%), Positives = 60/123 (48%), Gaps = 8/123 (6%) Query: 487 PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRE 546 P + F++AAD PGPP K + T +S+TL WS+ G S++ GY VE+ R+ Sbjct: 28077 PFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEI--RQ 28134 Query: 547 TLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVT 606 T +++G V T YVV +L PG+ Y F V N G P +++ V Sbjct: 28135 GEEEEWTTVSTKG------EVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQ 28188 Query: 607 VGD 609 D Sbjct: 28189 AKD 28191 Score = 63.7 bits (148), Expect = 3e-08 Identities = 167/814 (20%), Positives = 292/814 (35%), Gaps = 92/814 (11%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 D V Q NC + A +W++ + + IL ++ LR + Sbjct: 13575 DTRVKEQQEVVFNCEVNTEGAKA-KWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQ 13633 Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRL-EP-ESKQSAQGDTVVLECLPPRGSPE 137 A Y TN G + + ++ V E+ R+ EP + ++ + +V C R + Sbjct: 13634 AN-YNVSLTNHRG--ENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNV- 13689 Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIAT 195 + W KNG+ + FD + + VD L I+D D G Y AG +S Sbjct: 13690 -TLKWTKNGEEVPFD-NRVSYRVDKYKHMLTIKDCGFPDEGEYIV----TAGQDKSVAEL 13743 Query: 196 LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR-VKVLDD 254 L I + ED F C++ + +V W R+ G + G+ K D Sbjct: 13744 LIIEAPTEFVEHLEDQTVTEFDDAVFSCQLSREKA-NVKWYRN--GREIKEGKKYKFEKD 13800 Query: 255 GSLRLDNVILAD-EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313 GS+ +I+ D + CE V + L V + P + P +E+ Sbjct: 13801 GSIH--RLIIKDCRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVF 13858 Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373 + + + W N ++ G + + + + + I D+ + R Sbjct: 13859 LAELNKDKVEVQWL--RNNMVVVQG-DKHQMMSEGKIHRLQICDIKPRDQGEYRFI---- 13911 Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF 433 A R KL + + P I + + + P+ W+ Sbjct: 13912 ----AKDKEARAKLELAA-----APKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFK 13962 Query: 434 EGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIH 493 E E L + + + K D G Y V ++HGK + IN Sbjct: 13963 ENEPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGK--------AEGFIN---- 14010 Query: 494 FFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNT 553 + DV PGP D V+L+W + G S I+GY VE R + Sbjct: 14011 -LKVIDV---PGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVE---RRDIK---- 14059 Query: 554 PRNSRGWVVIARRVHQTHYVVKSLIPG-ITYMFIVRTENSHGLSGPSPVSDSVTVGDDSN 612 + WV+ R + V L G + Y+F V N G P + V ++ Sbjct: 14060 ---RKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPV----EAR 14112 Query: 613 SLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPL- 671 S ++ G N +TD ++ + L WE + + Y L Sbjct: 14113 SKYDVPGPP-----LNVTITD----------VNRFGVSLTWEPPEYDGGAEITNYVIELR 14157 Query: 672 DNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSR-VAQTLDDV 730 D +I ++ + + D+S +T + + +Y F + + GKPS + + D + Sbjct: 14158 DKTSIRWDTAMTVRAEDLSA-TVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPI 14216 Query: 731 P-DGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTV 789 PP+N+ ++V LKW PP L+ I GY ++ + + + N + Sbjct: 14217 ERPSPPVNLTSSDQTQSSVQLKWEPP-LKDGGSPILGY--IIERCE-EGKDNWIRCNMKL 14272 Query: 790 HQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQ 823 + +T L G Y +++AE G+ S+ Sbjct: 14273 VPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSE 14306 Score = 63.3 bits (147), Expect = 4e-08 Identities = 61/205 (29%), Positives = 85/205 (41%), Gaps = 14/205 (6%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64 YV + E P ++++ VTV +PA G P P I WYK L+ + L G Sbjct: 3232 YVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDG 3291 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR-----EEFRLEPESKQS 119 + L DA VY CEA N YG A + +A+L V V +E + P + + Sbjct: 3292 QEYTLLLIEA-FPEDAAVYTCEAKNDYGVA-TTSASLSVEVPEVVSPDQEMPVYPPAIIT 3349 Query: 120 AQGDTVVLECLPPR-----GSPEPNVYWKKNGQTLLFDGDSRM-HLVDGGNLVIQDARQT 173 DTV E P R + V W + + RM D L I +A Sbjct: 3350 PLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPE 3409 Query: 174 DAGRYQCIARNAAGTRESAIATLKI 198 D G Y +A NA G + S+ A L + Sbjct: 3410 DEGTYTFVASNAVG-QVSSTANLSL 3433 Score = 63.3 bits (147), Expect = 4e-08 Identities = 95/355 (26%), Positives = 144/355 (40%), Gaps = 45/355 (12%) Query: 269 EYSCEAENSVGAVSASGYLTV-------YDPPSINLSP---NSVNVESGN-VARFTCTAT 317 E+ A+N+ GA+SA T Y+ P+I L P + + +++G+ + + Sbjct: 21272 EFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISIL 21331 Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377 G+P P WS G I P D T+ ++LTI + D+ + +A N Sbjct: 21332 GKPLPKSSWSKAGKD--IRPS---DITQITSTPTS-SMLTIKYATRKDAGEYTI-TATNP 21384 Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437 G+ K+TV D PP GP + I +++ T TP P+ ++ Sbjct: 21385 FGTKVEHVKVTVL-DVPGPP-----GP----VEISNVSAEKATLTWTP-PLEDGGSPIKS 21433 Query: 438 LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHF--F 495 I R T+V +D+ S + + +Y++ + + + Sbjct: 21434 YILEKRETSRLLWTVVSEDIQ---SCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPV 21490 Query: 496 RAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPR 555 + D PGPP KP NVT + T+SW + G S I GY VE RE + Sbjct: 21491 KMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVE--RRE--------K 21540 Query: 556 NSRGWV-VIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 S WV I V V L G TY F V EN G+ PS SDSV + D Sbjct: 21541 KSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD 21595 Score = 62.9 bits (146), Expect = 5e-08 Identities = 112/466 (24%), Positives = 179/466 (38%), Gaps = 49/466 (10%) Query: 17 QPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75 +PL D+ V + A C + ++W+K G + I+ G + L + Sbjct: 13305 RPLTDLQVREKEMARFECELSRE-NAKVKWFKDGAEIKKGKKYDIISKGAVRIL-VINKC 13362 Query: 76 VHSDAGVYWCEATNSYGTARSRNATLHVAVLREE--FRLEPESKQSAQGDTVVLECLPPR 133 + D Y CE TAR+ + VL EE F + + ++ DT+ L C + Sbjct: 13363 LLDDEAEYSCEVR----TARTSGM---LTVLEEEAVFTKNLANIEVSETDTIKLVCEVSK 13415 Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRES 191 P V W K + ++ G + L +G LVIQ+A DAG Y C R + + Sbjct: 13416 --PGAEVIWYKGDEEIIETGRYEI-LTEGRKRILVIQNAHLEDAGNYNC--RLPSSRTDG 13470 Query: 192 AIATLKIH-IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RV 249 + K+H + I+ P+++ G F C + + P V W+R + G + Sbjct: 13471 KV---KVHELAAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRD--DKTLESGDKY 13524 Query: 250 KVLDDGSLR---LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306 V+ DG R + + L D G Y VGA A+ +LTV + I + V+ Sbjct: 13525 DVIADGKKRVLVVKDATLQDMGTYVV----MVGAARAAAHLTVIEKLRIVVPLKDTRVKE 13580 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 F C ++ N IF KY D V L I D +D Sbjct: 13581 QQEVVFNCEVNTEGAKAKWFR---NEEAIF---DSSKY-IILQKDLVYTLRIRDAHLDDQ 13633 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426 N V S N+ G + + ++D I+ +T+ KS+ F C + Sbjct: 13634 ANYNV-SLTNHRGENVKSAANLIVEEEDL--RIVEPLKDIETMEKKSV-TFWC-KVNRLN 13688 Query: 427 PIIAWYFEGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTCVA 469 + W GE + ++R + D L +KD D G Y A Sbjct: 13689 VTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTA 13734 Score = 61.3 bits (142), Expect = 2e-07 Identities = 94/380 (24%), Positives = 141/380 (37%), Gaps = 43/380 (11%) Query: 30 TLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88 T +C+ G P P I WYK G + + ++ G LR + D G+Y A+ Sbjct: 1309 TFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVV-LPEDEGIYTAFAS 1367 Query: 89 NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148 N G A+ + +EP + A LE + S P + ++ Sbjct: 1368 NIKGN----------AICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSP----RSVSRS 1413 Query: 149 LLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208 + +RM + AR + R + T ES + L KP + P Sbjct: 1414 PIRMSPARMSPARMSPARMSPARMSPGRRLE-------ETDESQLERL---YKPVFVLKP 1463 Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDG--SLRLDNVILA 265 G + F +V G P+P+ W N +V + +DG SL + + Sbjct: 1464 VSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPS 1523 Query: 266 DEGEYSCEAENSVGAVSASGYLTV-----YDPPSINLSPNSVNVESGNVARFTCTATGRP 320 D GE++ A+N G S S LTV P +VN++ G+ ATG P Sbjct: 1524 DSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSQLEMKVRATGNP 1583 Query: 321 EPTMFWSVEGNRTIIFPGMSRDKYHATAV--FDGVTVLTINDTDKNDSRNTIVCSAVNYA 378 P + W N II P KY + G L I+ T DS +A+N A Sbjct: 1584 NPDIVWL--KNSDIIVP----HKYPKIRIEGTKGEAALKIDSTVSQDSA-WYTATAINKA 1636 Query: 379 GSSFVRGKLTVTSDDDRPPP 398 G R K+ V + P P Sbjct: 1637 GRDTTRCKVNVEVEFAEPEP 1656 Score = 61.3 bits (142), Expect = 2e-07 Identities = 104/467 (22%), Positives = 180/467 (38%), Gaps = 50/467 (10%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 PY + D T L C + +P ++W+K G + + +++ A G + Sbjct: 12945 PYFTGKLQDYTGVEKDEVILQCEISKADAP-VKWFKDGK-EIKPSKNAVIKADGKKRMLI 13002 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131 + SD G Y C+ + + + ++R +E ++A+ +T + E Sbjct: 13003 LKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEISE--- 13059 Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGTR 189 + + WK G+ LL D + +G +LV+ + R G + AA + Sbjct: 13060 ----DDIHANWKLKGEALLQTPDCEIK-EEGKIHSLVLHNCRLDQTGG---VDFQAANVK 13111 Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249 SA +K + L+ +DV G + TF C + + +P V W G P +V Sbjct: 13112 SSAHLRVKPRVIG-LLRPLKDVTVTAGETATFDCELSYEDIP-VEWYLK-GKKLEPSDKV 13168 Query: 250 KVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP-NSVNVE 305 +G +L L +V L D GE A++ L V +PP P VE Sbjct: 13169 VPRSEGKVHTLTLRDVKLEDAGEVQLTAKD----FKTHANLFVKEPPVEFTKPLEDQTVE 13224 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG-VTVLTINDTDKN 364 G A C + R + W G + KY A DG V L I+D Sbjct: 13225 EGATAVLECEVS-RENAKVKWFKNGTEI-----LKSKKYEIVA--DGRVRKLVIHDCTPE 13276 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP-SNQTLPIKSMAVFPCTAIC 423 D + T C A ++ S L V PP + P ++ + K MA F C + Sbjct: 13277 DIK-TYTCDAKDFKTSC----NLNVV-----PPHVEFLRPLTDLQVREKEMARFEC-ELS 13325 Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDK---SDSGTYTC 467 + W+ +G + + + ++ + G + + ++K D Y+C Sbjct: 13326 RENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSC 13372 Score = 61.3 bits (142), Expect = 2e-07 Identities = 78/315 (24%), Positives = 118/315 (37%), Gaps = 38/315 (12%) Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360 ++NV + A C TG P+P + W +G + II G+ KY G L I Sbjct: 31863 NLNVRYQSNATLVCKVTGHPKPIVKWYRQG-KEIIADGL---KYRIQEFKGGYHQLIIAS 31918 Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420 +D+ A N GS L V P G + Sbjct: 31919 VTDDDA-TVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIP 31977 Query: 421 AICTPEPIIAWYFEGEALIQNHRRN---VTNDGTLVL--KDLDKSDSGTYTCVASSRHGK 475 P+P+I W +G+ LI N+ VT T ++ +++ D+G Y A +R G Sbjct: 31978 FSGKPDPVITWQ-KGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFG- 32035 Query: 476 YVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSI 535 +D DV+ +P PP +V+ SV L+W++ G S I Sbjct: 32036 --------IDQKTVE-------LDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKI 32080 Query: 536 LGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGL 595 Y VE + W+ + + +T Y V +L +Y F V EN GL Sbjct: 32081 TNYIVE----------KCATTAERWLRVG-QARETRYTVINLFGKTSYQFRVIAENKFGL 32129 Query: 596 SGPSPVSDSVTVGDD 610 S PS S+ +D Sbjct: 32130 SKPSEPSEPTITKED 32144 Score = 60.9 bits (141), Expect = 2e-07 Identities = 54/191 (28%), Positives = 84/191 (43%), Gaps = 9/191 (4%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFF 68 +AP+ E+ ++ V ATL C+ G P P ++WY+ G +++D + I G + Sbjct: 31853 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 31912 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEPESKQSAQGDTV 125 DA VY ATN G+ S A+L V V + LE A V Sbjct: 31913 QLIIASVTDDDATVYQVRATNQGGSV-SGTASLEVEVPAKIHLPKTLEGMGAVHALRGEV 31971 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQD-ARQTDAGRYQCIA 182 V +P G P+P + W+K GQ L+ + +V +LV + + DAG Y A Sbjct: 31972 VSIKIPFSGKPDPVITWQK-GQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCA 32030 Query: 183 RNAAGTRESAI 193 +N G + + Sbjct: 32031 KNRFGIDQKTV 32041 Score = 60.1 bits (139), Expect = 4e-07 Identities = 97/403 (24%), Positives = 157/403 (38%), Gaps = 58/403 (14%) Query: 425 PEPIIAWYFEGEALIQNHRR----NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480 P P + W +G+ L + R + TLV+KD ++D G Y S+ G Sbjct: 25662 PIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTK---- 25717 Query: 481 ALLVDSPINPNIHFFRAADVSSLPGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQ 539 PI V PGPP P+ VT L+W+ + G ++I Y Sbjct: 25718 ----SIPIT--------VKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYI 25765 Query: 540 VEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599 +E RET + W ++ V +Y V L+PG Y+F V N +G+ P Sbjct: 25766 IE--KRET--------SRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPL 25815 Query: 600 PVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFY 659 S VT + ++ G ++ E + +T + + A P+D + Sbjct: 25816 E-SGPVTACNP----YKPPGPPSTPEV--SAITKDSMVVTWARPVDDGGTE--------- 25859 Query: 660 YLEGLFIYFRPLDNIT-IEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKP 718 +EG + R + + + KT+ D+ +T L + YEF + G+P Sbjct: 25860 -IEGYILEKRDKEGVRWTKCNKKTL---TDLR-LRVTGLTEGHSYEFRVAAENAAGVGEP 25914 Query: 719 SNSRVAQTLDDV--PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDV 776 S V D P GPP N ++ + ++V L WS P + + GY VV + Sbjct: 25915 SEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKP-IYDGGAPVKGY--VVEVKEA 25971 Query: 777 PANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819 A++ T Q +T L Y+ +I A G+G Sbjct: 25972 AADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVG 26014 Score = 60.1 bits (139), Expect = 4e-07 Identities = 106/451 (23%), Positives = 182/451 (40%), Gaps = 61/451 (13%) Query: 177 RYQCIARNAAG-TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQ----CRVGGDPLP 231 +++ A N+AG + S + + + P G D + T ++T + R GG + Sbjct: 28755 QFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIV 28814 Query: 232 DVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVS----ASGYL 287 + G + + + + D E+ A N+VG +S +SG + Sbjct: 28815 GYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGII 28874 Query: 288 TVYD---PPSINLSP---NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341 D PP + P + + ++SG R GRP P + W +G R Sbjct: 28875 MTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEI-----EKR 28929 Query: 342 DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401 T V G T L + D + D R A N +GS+ K+ V D P ++ Sbjct: 28930 MNMEITDVL-GSTSLFVRDATR-DHRGVYTVEAKNASGSAKAEIKVKV---QDTPGKVV- 28983 Query: 402 NGPSNQT-LPIKSMAVF---PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL 457 GP T + + M ++ P C P I Y +I+ +R + +++D Sbjct: 28984 -GPIRFTNITGEKMTLWWDAPLNDGCAP---ITHY-----IIE--KRETSRLAWALIED- 29031 Query: 458 DKSDSGTYTCVASSRHGKYVWSGALL----VDSPINPNIHFFRAADVSSLPGPPTKPITH 513 K ++ +YT + +Y + + + V P++ + A ++P P P Sbjct: 29032 -KCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVV--AQIQYTVPDAPGIPEPS 29088 Query: 514 NVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV-VIARR-VHQTH 571 N+T S+TL+W++ G S I Y +E RE + S WV VI++R + +T Sbjct: 29089 NITGNSITLTWARPESDGGSEIQQYILE--RRE--------KKSTRWVKVISKRPISETR 29138 Query: 572 YVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602 + V L G Y F V EN+ G+ S +S Sbjct: 29139 FKVTGLTEGNEYEFHVMAENAAGVGPASGIS 29169 Score = 60.1 bits (139), Expect = 4e-07 Identities = 82/312 (26%), Positives = 130/312 (41%), Gaps = 39/312 (12%) Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363 V G V R T G+P P W+ EG +S+ AT+ + T L I + D+ Sbjct: 31075 VRQGGVIRLTIPIKGKPFPICKWTKEGQ------DISKRAMIATS--ETHTELVIKEADR 31126 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN-QTLPIKSMAV-FPCTA 421 DS T N G V K+ V + P GP + ++S+ V + A Sbjct: 31127 GDS-GTYDLVLENKCGKKAVYIKVRVIGSPNSP-----EGPLEYDDIQVRSVRVSWRPPA 31180 Query: 422 ICTPEPIIAWYFEGEALIQNHRRNVTND--GT-LVLKDLDKSDSGTYTCVASSRHGKYVW 478 I+ + E + + + + GT LV+K L ++ + A ++ G Sbjct: 31181 DDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGI--- 31237 Query: 479 SGALLVDSPINPNIHFFRAADVSSLPGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILG 537 S L + P+ P + P PP+ P +VT +SV+LSWS+ G S + G Sbjct: 31238 SKPLKSEEPVTPKTPL-------NPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTG 31290 Query: 538 YQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSG 597 Y +E R+ S + R+++ ++ T Y V L+P Y F + +N GLS Sbjct: 31291 YYIE---RKETSTDKWVRHNK------TQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSE 31341 Query: 598 PSPVSDSVTVGD 609 SP S+ V D Sbjct: 31342 TSPASEPVVCKD 31353 Score = 59.7 bits (138), Expect = 5e-07 Identities = 93/402 (23%), Positives = 162/402 (40%), Gaps = 57/402 (14%) Query: 425 PEPIIAWYFEGEALIQNHR---RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481 P P I WY + + L N N T+ ++++KD D+ +SG Y + G S Sbjct: 27827 PAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSA--SAT 27884 Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSILGYQV 540 + V + PGPP PI VT +TL W G + I Y V Sbjct: 27885 IRVQ--------------ILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIV 27930 Query: 541 EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600 E RET + W +++ + + +I G Y+F VR N +G+ P Sbjct: 27931 E--KRET--------SRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLE 27980 Query: 601 VSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYY 660 SDSV V ++ G+ T+ N +T ++ + PI + + Y+ Sbjct: 27981 -SDSV-VAKNAFVTPGPPGIPEVTKITKNSMT-----VVWSRPIADGGSDI-----SGYF 28028 Query: 661 LEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN 720 LE D ++ + K + + + ++T L + + Y++ + +G S Sbjct: 28029 LE-------KRDKKSLGW-FKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSE 28080 Query: 721 -SRVAQTLDDV-PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPA 778 S + D + P GPP I + +++ L WS P +TGY V + + Sbjct: 28081 PSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYD-GGSAVTGYVVEIRQGE--- 28136 Query: 779 NKSMVAINTTVH-QATSLIMTNLTSGVSYSVQIAAETIIGLG 819 + ++T + T +++NL GV+Y +++A G G Sbjct: 28137 EEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQG 28178 Score = 59.7 bits (138), Expect = 5e-07 Identities = 60/224 (26%), Positives = 94/224 (41%), Gaps = 22/224 (9%) Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW 142 Y+C T + R T+ + EF L +K + G+ V + PEP+V W Sbjct: 32594 YYCRRTMK--KIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFG-VTITVHPEPHVTW 32650 Query: 143 KKNGQTLL-FDGDSRMHLV-DGG--NLVIQDARQTDAGRYQCIARNAAGTRE-SAIATLK 197 K+GQ + D D + D G L I D Y +ARN G A T+ Sbjct: 32651 YKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVT 32710 Query: 198 IH-------IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RV 249 +H ++P + Q G SV F+ RV G P P + W + G + LG + Sbjct: 32711 LHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKD--GQPLSLGPNI 32768 Query: 250 KVLDDG----SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 +++ +G +L + + + D G Y A N+ G+ S +L V Sbjct: 32769 EIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 32812 Score = 59.3 bits (137), Expect = 6e-07 Identities = 100/398 (25%), Positives = 156/398 (39%), Gaps = 57/398 (14%) Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481 P P I+W +GE L Q R NV T L +K+ +K D G YT A++ G + + Sbjct: 25266 PRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLS 25325 Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSILGYQV 540 ++V PGPP P+ + V+ V +SW G I Y V Sbjct: 25326 VIV----------------LEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIV 25369 Query: 541 EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600 E R+T + W +++ V +T + L G Y F + EN +G S +P Sbjct: 25370 E--KRDTTTTT--------WHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKS--AP 25417 Query: 601 VSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDH-IVELIEATPIDSKTIKLMWEILNFY 659 + + ++ G T + +I D +V+ E P++ K++ Y Sbjct: 25418 LDSKAVIVQYP---FKEPGPPG-TPFVTSISKDQMLVQWHE--PVNDGGTKIIG-----Y 25466 Query: 660 YLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPS 719 +LE + ++I KT + F+ T L + +YEF + GKPS Sbjct: 25467 HLEQ-----KEKNSILWVKLNKTPIQDTK---FKTTGLDEGLEYEFKVSAENIVGIGKPS 25518 Query: 720 NSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPAN 779 D P PP E ++ V LKW P ITGY +V D+P Sbjct: 25519 KVSECFVARD-PCDPPGRPEAIVITRNNVTLKWKKPAYD-GGSKITGY--IVEKKDLPDG 25574 Query: 780 KSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817 + M A T V + T ++ L Y ++ A G Sbjct: 25575 RWMKASFTNVLE-TEFTVSGLVEDQRYEFRVIARNAAG 25611 Score = 58.8 bits (136), Expect = 8e-07 Identities = 77/355 (21%), Positives = 140/355 (39%), Gaps = 30/355 (8%) Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAI-AT 195 +V W NG L + R + V G + L I+ A D G CI++ G + T Sbjct: 33994 DVKWVLNGVELTNSEEYR-YGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLT 34052 Query: 196 LKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGGGNMPLGRV 249 L + P I+ P G +V F C + G+P P++ W ++ + N+ + R Sbjct: 34053 LSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRS 34112 Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDPPS--INLSPNSVNV 304 + + SL + N ++D G+Y+ +A+N G SA+ L V + PS + L + Sbjct: 34113 R--NVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTS 34170 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 G+ + + + + F S + M+ K+ A+ ++ + + + + Sbjct: 34171 LQGSFSSQSVQMSASKQEASFSSFSSSSA---SSMTEMKF-ASMSAQSMSSMQESFVEMS 34226 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424 S + + S+ K + PP I PS+ ++ + C Sbjct: 34227 SSSFMGISNMTQLESSTSKMLKAGIRG----IPPKIEALPSDISIDEGKVLTVACAFTGE 34282 Query: 425 PEPIIAWYFEGEALIQN-----HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 P P + W G + H N + TL++ D+ K D G YT + G Sbjct: 34283 PTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 34337 Score = 58.4 bits (135), Expect = 1e-06 Identities = 91/356 (25%), Positives = 132/356 (37%), Gaps = 47/356 (13%) Query: 6 VTSGEAPYIIE---QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL- 61 +T G+ P + P+D V + A C G+ + W K + S I Sbjct: 9073 LTEGKNPPFFDIRLAPVDAVVG--ESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISY 9130 Query: 62 --PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLE-PES 116 + L L+ G D+G Y C A N G S A L++ ++ F E+ Sbjct: 9131 LENSAHLTVLKVDKG----DSGQYTCYAVNEVGKD-SCTAQLNIKERLIPPSFTKRLSET 9185 Query: 117 KQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ--DARQTD 174 + +G++ LE GS V W KN + + + + LV+Q A D Sbjct: 9186 VEETEGNSFKLEGRVA-GSQPITVAWYKNNIEIQPTSNCEITFKNN-TLVLQVRKAGMND 9243 Query: 175 AGRYQCIARNAAGTRESAIATLKIHIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDP 229 AG Y C N AG SA+ T I IK P V G V C V G Sbjct: 9244 AGLYTCKVSNDAG---SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSE 9300 Query: 230 LPDVLWRRSAGGGNMPLGRVKV-LDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGY 286 + W + AG P R G+ L L +V AD G+Y C+A N G+ + Sbjct: 9301 PIRIQWLK-AGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSK 9359 Query: 287 LTVYDPPSIN---------------LSPNSVNVESGNVARFTCTATGRPEPTMFWS 327 +T+ D P++ P S+ V A F G P P + W+ Sbjct: 9360 VTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWT 9415 Score = 58.4 bits (135), Expect = 1e-06 Identities = 109/456 (23%), Positives = 174/456 (38%), Gaps = 59/456 (12%) Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS--MAVFPCTAICTPEP 427 I +AVN + S +T+ +++ PP I + L +K+ T P P Sbjct: 20194 IARTAVNISPPSEPSDPVTILAENV-PPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMP 20252 Query: 428 IIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 ++W +G L + N TL L +++ DSG YT A + G S + + Sbjct: 20253 TVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSK--SATIKL 20310 Query: 485 DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFS 544 V PGPP + + LSW + G S I Y V+ Sbjct: 20311 K--------------VLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVD--K 20354 Query: 545 RETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDS 604 RET N W ++ V T V+ LI G Y F + EN +G+ P + Sbjct: 20355 RETSRPN--------WAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPA 20406 Query: 605 VTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGL 664 + + + ++ G + +NI DH+ + P D + +L + + Sbjct: 20407 I-----AKNPYDPPGRCDPPVI-SNITKDHMT-VSWKPPADDGGSPITGYLLEKRETQAV 20459 Query: 665 FIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN-SRV 723 N T + K I+ + T L++ T+YEF + K GKPS+ S+ Sbjct: 20460 --------NWT-KVNRKPIIERT----LKATGLQEGTEYEFRVTAINKAGPGKPSDASKA 20506 Query: 724 AQTLD-DVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSM 782 A D P PP +++ ++V L W P + II GY V V D + + Sbjct: 20507 AYARDPQYPPAPPAFPKVYDTTRSSVSLSWGKPAYDGGSPII-GYLVEVKRAD---SDNW 20562 Query: 783 VAINTTVH-QATSLIMTNLTSGVSYSVQIAAETIIG 817 V N + Q T +T L Y ++ A IG Sbjct: 20563 VRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIG 20598 Score = 58.4 bits (135), Expect = 1e-06 Identities = 72/290 (24%), Positives = 113/290 (38%), Gaps = 21/290 (7%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 +AP I QP + Q C G PSP I W+K + + ++ SI + ++ L Sbjct: 34059 DAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSL 34118 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 + V SD+G Y +A N G S A+L V L EE E + S GDT + Sbjct: 34119 EIRNASV-SDSGKYTIKAKNFRGQC-SATASLMVLPLVEEPSREVVLRTS--GDTSLQGS 34174 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG-- 187 + + + + S M + ++ Q + + + G Sbjct: 34175 FSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGIS 34234 Query: 188 ----TRESAIATLKIHIK---PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 S LK I+ P + P D+ G +T C G+P P+V W S G Sbjct: 34235 NMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTW--SCG 34292 Query: 241 G---GNMPLGR--VKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSAS 284 G + GR ++ DD +L + +V D G Y+ N G+ SA+ Sbjct: 34293 GRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSAT 34342 Score = 58.0 bits (134), Expect = 1e-06 Identities = 79/324 (24%), Positives = 134/324 (41%), Gaps = 35/324 (10%) Query: 500 VSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRG 559 VS +P P K +VT ++VTL+W + G S + GY +E T R Sbjct: 30558 VSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGT---------ERW 30608 Query: 560 WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTG 619 V+ + + V SL G Y+F +R +N G+S P +VTV D + Sbjct: 30609 MKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQD--LRVLPTID 30666 Query: 620 VSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYE 679 +S + ++ VEL+ PI + ++ G + R + +T+E Sbjct: 30667 LSTMPQKTIHVPAGRPVELV--IPIAGRPPPAA-----SWFFAGSKL--RESERVTVETH 30717 Query: 680 MKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIE 739 K + T++R +Y L K G S + + + D P P I+ Sbjct: 30718 TKVAKLT-----IRETTIRDTGEYTLEL----KNVTGTTSET-IKVIILDKPGPPTGPIK 30767 Query: 740 MFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTN 799 + ++ T++ + W PPEL ++GY VV D + ++ +V ++T T Sbjct: 30768 IDEIDATSITISWEPPELD-GGAPLSGY--VVEQRDA-HRPGWLPVSESVTRST-FKFTR 30822 Query: 800 LTSGVSYSVQIAAETIIGLGPFSQ 823 LT G Y ++AA G+G + Q Sbjct: 30823 LTEGNEYVFRVAATNRFGIGSYLQ 30846 Score = 57.6 bits (133), Expect = 2e-06 Identities = 89/364 (24%), Positives = 144/364 (39%), Gaps = 37/364 (10%) Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYD------PPSINLSPNSVNVESGNVARF 312 +++++ E E+ +A N+ G S + D PPSI+L + VE G Sbjct: 17005 VEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLK-EFMEVEEGTNVNI 17063 Query: 313 TCTATGRPEPTMFW-SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371 G P PT+ W + + D + V D L I + ++D+ Sbjct: 17064 VAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDT-GLYT 17122 Query: 372 CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431 +AVN G++ +L V RP P + GP + +S++ T P Sbjct: 17123 ITAVNNLGTASKEMRLNVLG---RPGPPV--GP----IKFESVSADQMTLSWFPPKD--- 17170 Query: 432 YFEGEALIQNH--RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVW----SGALLVD 485 +G + I N+ + N T V + + TYT +YV+ + Sbjct: 17171 --DGGSKITNYVIEKREANRKTWVHVSSEPKEC-TYTIPKLLEGHEYVFRIMAQNKYGIG 17227 Query: 486 SPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSR 545 P++ A ++ S+PG P KP +VT S+T++W + G S + GY +E+ + Sbjct: 17228 EPLDSEPE--TARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEM--K 17283 Query: 546 ETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605 +T S R +R I Y V LI G Y F V N+ G+ S SD Sbjct: 17284 DTTS-KRWKRVNRD--PIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPA 17340 Query: 606 TVGD 609 T D Sbjct: 17341 TARD 17344 Score = 57.6 bits (133), Expect = 2e-06 Identities = 36/101 (35%), Positives = 47/101 (46%), Gaps = 11/101 (10%) Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGW-V 561 +PGPP KP+ +NVT ++L+W G S + G+ VE RNS W Sbjct: 28683 IPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVE----------KKERNSILWQK 28732 Query: 562 VIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602 V + Y L+ G+ Y F V ENS GLS PS S Sbjct: 28733 VNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPS 28773 Score = 57.2 bits (132), Expect = 3e-06 Identities = 90/342 (26%), Positives = 138/342 (40%), Gaps = 51/342 (14%) Query: 273 EAENSVGAVSASGYLTVYDPPSINLSP---NSVNVESGNVARFTCTATGRPEPTMFWSVE 329 E S GA++A + DPP I++ P +++ V +G + G+P PT+ W ++ Sbjct: 23451 EPSESTGAITARDEV---DPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQW-IK 23506 Query: 330 GNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389 G++ + +R + +T D T L++ D + DS N I+ A N AG V + V Sbjct: 23507 GDQEL--SNTARLEIKST---DFATSLSVKDAVRVDSGNYIL-KAKNVAGERSVTVNVKV 23560 Query: 390 TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP------EPIIAWYFEGEALIQNHR 443 DRP GP + I + CT P II + E + Sbjct: 23561 L---DRP------GPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVW 23611 Query: 444 RNV-TNDGTLVLK--DLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADV 500 V N TL K L + + T+ +A +++G G L P+ F Sbjct: 23612 TVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGV----GEPLESEPVVAKNPFV----- 23662 Query: 501 SSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGW 560 +P P P VT S+ + W + G S ILGY +E +E + + Sbjct: 23663 --VPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHK----- 23715 Query: 561 VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602 R + + V LI Y F V EN+ GLS PSP S Sbjct: 23716 ----RLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPS 23753 Score = 57.2 bits (132), Expect = 3e-06 Identities = 75/320 (23%), Positives = 126/320 (39%), Gaps = 33/320 (10%) Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352 P + + +S +V+ G + +GRP+PT+ W+ +G P + + T D Sbjct: 24157 PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDG-----LPLKQTTRINVTDSLD- 24210 Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP--PIITNGPSNQTLP 410 +T L+I +T K+D + A N G ++ VT D PP P+ + S +++ Sbjct: 24211 LTTLSIKETHKDDGGQYGITVA-NVVGQKTASIEI-VTLDKPDPPKGPVKFDDVSAESIT 24268 Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470 + T C I + + + TL + L + A Sbjct: 24269 LSWNPPL-YTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAE 24327 Query: 471 SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530 +R+G+ S AL D PI + PGPP P ++ S+ + W + Sbjct: 24328 NRYGQ---SFALESD-PIVAQYPYKE-------PGPPGTPFATAISKDSMVIQWHEPVNN 24376 Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMFIVRT 589 G S ++GY +E RNS W + + +H T + ++L GI Y F V Sbjct: 24377 GGSPVIGYHLE----------RKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYA 24426 Query: 590 ENSHGLSGPSPVSDSVTVGD 609 EN G+ S S+ D Sbjct: 24427 ENIVGVGKASKNSECYVARD 24446 Score = 57.2 bits (132), Expect = 3e-06 Identities = 73/327 (22%), Positives = 124/327 (37%), Gaps = 23/327 (7%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I+ D TV+ A +A G P P W K G + + G FFL Sbjct: 33779 PVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLE- 33837 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR----EEFRLEPESKQSAQGDTVVL 127 H SD+G+Y C NS G+ S + L + ++ ++ + S+ + Q VV Sbjct: 33838 IHKTDTSDSGLYTCTVKNSAGSV-SSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQ 33896 Query: 128 ECLPPRG--SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 E + + S E + K+ + L ++ L+ ++ +++ A + + Sbjct: 33897 EEISQKALRSEEIKMSEAKSQEKLALKEEASKVLIS------EEVKKSAATSLEKSIVHE 33950 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW-RRSAGGGNM 244 T+ S A+ ++ + + G + + + G DV W N Sbjct: 33951 EITKTSQ-ASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG--ATDVKWVLNGVELTNS 34007 Query: 245 PLGRVKVL-DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT----VYDPPSINLSP 299 R V D +L + DEG +C ++ G V LT + D P+ P Sbjct: 34008 EEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQP 34067 Query: 300 NSVNVESGNVARFTCTATGRPEPTMFW 326 S N+ G FTC +G P P + W Sbjct: 34068 RSQNINEGQNVLFTCEISGEPSPEIEW 34094 Score = 56.8 bits (131), Expect = 3e-06 Identities = 94/378 (24%), Positives = 138/378 (36%), Gaps = 24/378 (6%) Query: 178 YQCIARNAAG-----TRESAIATLKIHIK-PYLITGPE--DV-VAQTGSSVTFQCRVGGD 228 ++ IARNAAG + S T + I P P+ DV V G + + + G Sbjct: 25602 FRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGK 25661 Query: 229 PLPDVLWRRSAGGGNMPLGRVKV---LDDGSLRLDNVILADEGEYSCEAENSVGAVSASG 285 P+PDV+W + R+++ + +L + + I D G+Y + N G S Sbjct: 25662 PIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPI 25721 Query: 286 YLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345 + V D P P V V C P P + II + Sbjct: 25722 TVKVLDRPGPPEGPLKVT----GVTAEKCYLAWNP-PLQDGGANISHYII-EKRETSRLS 25775 Query: 346 ATAVFDGVTVLTINDTDKNDSRNTIV-CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404 T V V L T I AVN G VT+ + PP + P Sbjct: 25776 WTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTP 25835 Query: 405 SNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGT 464 + SM V + I Y + + R N TL DL +G Sbjct: 25836 EVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT--DLRLRVTGL 25893 Query: 465 YTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSW 524 S + A V P P++ F+RA D PGPP+ P + + +SV+L+W Sbjct: 25894 TE--GHSYEFRVAAENAAGVGEPSEPSV-FYRACDALYPPGPPSNPKVTDTSRSSVSLAW 25950 Query: 525 SQNNKIGSSSILGYQVEV 542 S+ G + + GY VEV Sbjct: 25951 SKPIYDGGAPVKGYVVEV 25968 Score = 56.4 bits (130), Expect = 4e-06 Identities = 87/353 (24%), Positives = 141/353 (39%), Gaps = 41/353 (11%) Query: 269 EYSCEAENSVGAVS----ASGYLTVYD---PPSINLSP---NSVNVESGNVARFTCTATG 318 E+ A N+ +VS ++G + V D PP + + + + V++G V + G Sbjct: 26683 EFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAG 26742 Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378 RP P + W+ +G I +R + +T D T+LT+ D + D+ V + N A Sbjct: 26743 RPLPVISWAKDG---IEIEERARTEIIST---DNHTLLTVKDCIRRDT-GQYVLTLKNVA 26795 Query: 379 GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438 G+ V V D+P GP L I + C+ + P + + Sbjct: 26796 GTRSVAVNCKVL---DKP------GPPAGPLEINGLTAEKCS-LSWGRPQEDGGADIDYY 26845 Query: 439 IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH-GKYVWSGALLVDSPINPNIHFFRA 497 I R T+ +L + + + + + V P+ +A Sbjct: 26846 IVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVA--IKA 26903 Query: 498 ADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNS 557 D ++P PPT +VT S+TL WS+ G S I GY +E RE +NS Sbjct: 26904 LDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIE--RRE--------KNS 26953 Query: 558 RGWVVIARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 WV + ++ V+ L G Y + V EN+ GLS PS S + D Sbjct: 26954 LRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAED 27006 Score = 56.0 bits (129), Expect = 6e-06 Identities = 120/556 (21%), Positives = 206/556 (37%), Gaps = 70/556 (12%) Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRH 473 FP P P W +G + + V D L +K+ + D+G Y S+ Sbjct: 18457 FPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAA 18516 Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITH-NVTDTSVTLSWSQNNKIGS 532 G + +H V +PGPPT PI +VT +T+SW G Sbjct: 18517 GSKTVA------------VHL----TVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGG 18560 Query: 533 SSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENS 592 S ++ Y VE +T +++ W V++ +T + L G Y+F VR EN Sbjct: 18561 SPVINYIVEK--------QDTRKDT--WGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENK 18610 Query: 593 HGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLM 652 G+ GP P+ + TV S G T+ N T + Sbjct: 18611 IGV-GP-PLDSTPTVAKHKFSPPSPPGKPVVTDITENAAT------------------VS 18650 Query: 653 WEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEF--FLIPF 710 W + + Y+ +T ++ D+ F +T L + YEF F Sbjct: 18651 WTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLK-FRVTGLYEGNTYEFRVFAENL 18709 Query: 711 YKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVV 770 + PS+ + P GPPIN ++ + T L W+ P L I GY VV Sbjct: 18710 AGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKP-LSDGGSPILGY-VV 18767 Query: 771 VNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNID 830 A + + + + Q + + L G Y +I A I+G G + + Sbjct: 18768 ECQKPGTAQWNRINKDELIRQC-AFRVPGLIEGNEYRFRIKAANIVGEGEPRE-----LA 18821 Query: 831 SRSVGLDLLSRYPMNGEVSIVAGDFVMETWFYFLIGAIVLFKIIVIAGIIYVRKYNIFAK 890 + D+L +P E+ + D V+ I + K I + ++ + + Sbjct: 18822 ESVIAKDIL--HPPEVELDVTCRD-VITVRVGQTIRILARVKGRPEPDITWTKEGKVLVR 18878 Query: 891 KSALPNIYDSNGTSLVTQMNIKAAVSLSHP--LTSCYNKNTVTKTESLLWMENQPGVCLS 948 + + I D ++ IK AV H + S N + + +++ + ++PG C + Sbjct: 18879 EKRVDLIQDLPR----VELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQN 18934 Query: 949 GNQTSQSKEKTNFEYD 964 T+ +KE ++ Sbjct: 18935 LKVTNVTKENCTISWE 18950 Score = 55.6 bits (128), Expect = 8e-06 Identities = 64/270 (23%), Positives = 100/270 (37%), Gaps = 16/270 (5%) Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313 D SL+ E E +V A G L D P I+ E G++ T Sbjct: 4250 DESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLT 4309 Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373 + T E W E + P S +K+ + T L I+ + D + VC Sbjct: 4310 TSITNAKEVN--WYFENK---LVP--SDEKFKCLQDQNTYT-LVIDKVNTEDHQGEYVCE 4361 Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF 433 A+N +G + KLTV R P+I + + +A F C P W+ Sbjct: 4362 ALNDSGKTATSAKLTVVK---RAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFK 4418 Query: 434 EGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490 G + ++ + ++ + +L + D G YTC AS+ +G + L V P Sbjct: 4419 AGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPP 4478 Query: 491 NIHFFRAADVSSLPGPPTKPITHNVTDTSV 520 R +++ G K I VT T V Sbjct: 4479 TF-LSRPKSLTTFVGKAAKFIC-TVTGTPV 4506 Score = 55.2 bits (127), Expect = 1e-05 Identities = 51/186 (27%), Positives = 81/186 (43%), Gaps = 27/186 (14%) Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483 P P + W + GE+L + + ++ L++ ++++ DSG Y + G S + Sbjct: 22815 PAPEVKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSG----SKSAF 22870 Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543 V+ R D PGPP VT TSVTL+W G S I Y VE Sbjct: 22871 VN---------VRVLDT---PGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVE-- 22916 Query: 544 SRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603 RE+ + + +A H+T + V L G +Y F V EN +G+ P+ ++ Sbjct: 22917 KRES--------TRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAE 22968 Query: 604 SVTVGD 609 SV + Sbjct: 22969 SVKASE 22974 Score = 55.2 bits (127), Expect = 1e-05 Identities = 76/307 (24%), Positives = 117/307 (38%), Gaps = 36/307 (11%) Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363 V +G AR GRP P + WS E G DK + T L+I++ D+ Sbjct: 24963 VRAGGSARIHIPFKGRPTPEITWSRE-------EGEFTDKVQIEKGVN-YTQLSIDNCDR 25014 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423 ND+ I+ N +GS +TV D PP Q L +K + + Sbjct: 25015 NDAGKYIL-KLENSSGSK--SAFVTVKVLDTPGPP--------QNLAVKEVRKDSAFLVW 25063 Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483 P PII +G A ++N+ + ++ S T V + G + + Sbjct: 25064 EP-PII----DGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMA 25118 Query: 484 VDS-PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEV 542 + + + A + P PP K +V+ TS +L W + G S +LGY VE+ Sbjct: 25119 ENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEM 25178 Query: 543 FSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602 P+ + W ++A + VV L G Y F V+ N G S P + Sbjct: 25179 ----------QPKGTEKWSIVAES-KVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLG 25227 Query: 603 DSVTVGD 609 V D Sbjct: 25228 VPVIAKD 25234 Score = 54.8 bits (126), Expect = 1e-05 Identities = 107/394 (27%), Positives = 160/394 (40%), Gaps = 60/394 (15%) Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYT-CVASSRHGKYVWSG 480 P+ + W +G+ L + R NV++ T L +K+ K D GTY CV++S +G Sbjct: 26349 PQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNS-------AG 26401 Query: 481 ALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQV 540 ++ V PI V PGPP V+ S+T+SW+ G I Y V Sbjct: 26402 SITV--PIT--------IIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIV 26451 Query: 541 EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600 E +ET S W ++++ V +T + L G Y F V EN +G S S Sbjct: 26452 E--KKET--------TSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSE 26501 Query: 601 VSDSVTVGDDSNSLWEGT-GVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFY 659 S V S GT V ++T ++ +L V + + S+ I E Sbjct: 26502 SSAVVAEYPFSPPGPPGTPKVVHAT--KSTMLVTWQVPVNDG---GSRVIGYHLE----- 26551 Query: 660 YLEGLFIYFRPLDNITI-EYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKP 718 Y E I + + I I + +MK VSG + + +Y Y + GK Sbjct: 26552 YKERSSILWSKANKILIADTQMK-------VSGLDEGLMYEYRVYAENIAGI-----GKC 26599 Query: 719 SNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPA 778 S S D P PP E+ + +V LKWS P ITGY +V ++P Sbjct: 26600 SKSCEPVPARD-PCDPPGQPEVTNITRKSVSLKWSKPHYD-GGAKITGY--IVERRELPD 26655 Query: 779 NKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAA 812 + + N T Q T +T LT Y ++ A Sbjct: 26656 GR-WLKCNYTNIQETYFEVTELTEDQRYEFRVFA 26688 Score = 54.8 bits (126), Expect = 1e-05 Identities = 97/440 (22%), Positives = 164/440 (37%), Gaps = 58/440 (13%) Query: 389 VTSDDDRPPPIITNGPSN-QTLPIKSMAVFPCTAICT--PEPIIAWYFEGEALIQNHRRN 445 + + D+ PPI+ GP L IKS A+ P P + W+ +G + + Sbjct: 28874 IMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNME 28933 Query: 446 VTN---DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSS 502 +T+ +L ++D + G YT A + SG+ + + V Sbjct: 28934 ITDVLGSTSLFVRDATRDHRGVYTVEAKNA------SGSAKAEIKVK----------VQD 28977 Query: 503 LPGPPTKPITH-NVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV 561 PG PI N+T +TL W G + I Y +E RET + W Sbjct: 28978 TPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIE--KRET--------SRLAWA 29027 Query: 562 VIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVS 621 +I + Y LI G Y F V N G+ P+ V ++ + G+ Sbjct: 29028 LIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVG--RPLDSDPVVAQIQYTVPDAPGIP 29085 Query: 622 NSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMK 681 + +T + + L A P ++ IL + + + Sbjct: 29086 EPSN-----ITGNSITLTWARPESDGGSEIQQYILE------------RREKKSTRWVKV 29128 Query: 682 TILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN-SRVAQTLDDV-PDGPPINIE 739 + F++T L + +YEF ++ G S SR+ + + V P GPP ++ Sbjct: 29129 ISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVK 29188 Query: 740 MFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTN 799 + + TTV L+WS P II GY + + D+ +N T +T+ Sbjct: 29189 VTDTSKTTVSLEWSKPVFDGGMEII-GYIIEMCKADL---GDWHKVNAEACVKTRYTVTD 29244 Query: 800 LTSGVSYSVQIAAETIIGLG 819 L +G Y +++A G G Sbjct: 29245 LQAGEEYKFRVSAINGAGKG 29264 Score = 54.4 bits (125), Expect = 2e-05 Identities = 49/189 (25%), Positives = 70/189 (37%), Gaps = 13/189 (6%) Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV-FD 351 P L P S G ARF GRP P FW +G + + D H + D Sbjct: 1457 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIV------NDYTHKVVIKED 1510 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411 G L I +DS V A N AG S + LTV + + + P+ N + Sbjct: 1511 GTQSLIIVPATPSDSGEWTVV-AQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKE 1569 Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-----LVLKDLDKSDSGTYT 466 S A P P I W + ++ + + +GT L + DS YT Sbjct: 1570 GSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYT 1629 Query: 467 CVASSRHGK 475 A ++ G+ Sbjct: 1630 ATAINKAGR 1638 Score = 54.0 bits (124), Expect = 2e-05 Identities = 54/222 (24%), Positives = 85/222 (38%), Gaps = 29/222 (13%) Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT--PEPIIAWYFEGEALIQNHRRNV 446 + + + P + +TL +K+ A F T P P + W L + Sbjct: 27103 IAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDT 27162 Query: 447 TNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPG 505 T+ T L +++ +++DSG YT + V S A L V PG Sbjct: 27163 TDSRTSLTIENANRNDSGKYTLTIQN-----VLSAASLT-----------LVVKVLDTPG 27206 Query: 506 PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565 PPT +VT S LSW G + + Y +E RE + + WV + Sbjct: 27207 PPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIE--KREA--------SKKAWVSVTN 27256 Query: 566 RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607 ++ Y V +L G Y F V EN G+ P+ + V + Sbjct: 27257 NCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKI 27298 Score = 54.0 bits (124), Expect = 2e-05 Identities = 98/409 (23%), Positives = 156/409 (38%), Gaps = 59/409 (14%) Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHG-KYVWSG 480 PEP I W + L + ++ G T V+K D+SDSG YT + G K V Sbjct: 30002 PEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVM 30061 Query: 481 ALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQV 540 ++DSP GP K VT TL+WS + G + I Y V Sbjct: 30062 VKVLDSP-----------------GPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIV 30104 Query: 541 EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600 E RET N WV++ YVV LI Y+F VR N +G P Sbjct: 30105 E--RRETSRLN--------WVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPG--VP 30152 Query: 601 VSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYY 660 V V +S ++ G+ +HI+ I+ T +S EI N+ Sbjct: 30153 VESEPIVARNSFTIPSPPGIPEEV----GTGKEHII--IQWTKPESDGGN---EISNYLV 30203 Query: 661 --LEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKP 718 E + + ++ + Y+ + ++TSL + Y+F + +P Sbjct: 30204 DKREKKSLRWTRVNKDYVVYDTR----------LKVTSLMEGCDYQFRVTAVNAAGNSEP 30253 Query: 719 SNSR--VAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDV 776 S + ++ GPP + ++ L W+ P I+ GY + + D Sbjct: 30254 SEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIV-GYVLEMQEKDT 30312 Query: 777 PANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825 V N T+ T + +L G YS ++AA + G+ +S+ + Sbjct: 30313 D-QWYRVHTNATIRN-TEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESI 30359 Score = 53.6 bits (123), Expect = 3e-05 Identities = 50/186 (26%), Positives = 78/186 (41%), Gaps = 27/186 (14%) Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKD-LDKSDSGTYTCVASSRHGKYVWSGALL 483 P P+I W +G L + T +L++ D +++ D+G YT A ++ GK S +L Sbjct: 30401 PPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKK--SATVL 30458 Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543 V V PGP V+ SVT++W G + + Y VE Sbjct: 30459 V--------------KVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVE-- 30502 Query: 544 SRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603 RE R + + + +T Y + L+ G Y F V EN +G+ P SD Sbjct: 30503 KREAA--------MRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSD 30554 Query: 604 SVTVGD 609 +V V + Sbjct: 30555 AVLVSE 30560 Score = 53.6 bits (123), Expect = 3e-05 Identities = 73/376 (19%), Positives = 145/376 (38%), Gaps = 24/376 (6%) Query: 119 SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGR 177 + D+V + G P P W K+G+ + G ++ GG L I +D+G Sbjct: 33789 TVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGL 33848 Query: 178 YQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 Y C +N+AG S ++ K+ IK T + V Q S +T Q + + + + ++ Sbjct: 33849 YTCTVKNSAG---SVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKA---VVQEEISQK 33902 Query: 238 SAGGGNMPLGRVKVLDDGSLR--LDNVILADEGEYSC--EAENSV--GAVSASGYLTVYD 291 + + + K + +L+ V++++E + S E S+ ++ + + Sbjct: 33903 ALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEV 33962 Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 + S + R A + W + G ++ + + V Sbjct: 33963 RTHAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVE------LTNSEEYRYGVSG 34016 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411 LTI D + C + G + LT++ + P I+ P +Q + Sbjct: 34017 SDQTLTIKQASHRD-EGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQ-PRSQNINE 34074 Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCV 468 +F C P P I W+ + + +++ N +L +++ SDSG YT Sbjct: 34075 GQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIK 34134 Query: 469 ASSRHGKYVWSGALLV 484 A + G+ + +L+V Sbjct: 34135 AKNFRGQCSATASLMV 34150 Score = 53.2 bits (122), Expect = 4e-05 Identities = 35/118 (29%), Positives = 49/118 (41%), Gaps = 5/118 (4%) Query: 177 RYQCIARNAAGTRESAIATLKIHIK---PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233 R++ + A E+A + I P L++G ++V G SVT +C + G P P V Sbjct: 915 RFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTV 974 Query: 234 LWRRSAGGGNMPLGRVKVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTV 289 W R + G RL D G ++C A N G VS S YL V Sbjct: 975 TWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032 Score = 53.2 bits (122), Expect = 4e-05 Identities = 35/102 (34%), Positives = 47/102 (46%), Gaps = 10/102 (9%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 P PP KP +V TSV L+W++ G + I Y +E+ T WV + Sbjct: 14911 PWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDE----------WVRV 14960 Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605 A V T +++ L+ G Y F VR N G S PS SD V Sbjct: 14961 AEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPV 15002 Score = 53.2 bits (122), Expect = 4e-05 Identities = 29/95 (30%), Positives = 47/95 (49%), Gaps = 4/95 (4%) Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS- 256 I KP ++TG +D + S F + G+P P +W + G G+ K+ +D Sbjct: 33775 ISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKD-GKAITQGGKYKLSEDKGG 33833 Query: 257 --LRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 L + +D G Y+C +NS G+VS+S LT+ Sbjct: 33834 FFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 33868 Score = 52.8 bits (121), Expect = 5e-05 Identities = 101/478 (21%), Positives = 180/478 (37%), Gaps = 46/478 (9%) Query: 13 YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRAT 72 + + +P + V AT + GG P P ++W KG ++ R + G Sbjct: 9382 FFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEI 9441 Query: 73 HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP 132 +D+G+Y C A N +G S N L V +++ ++E + + + T +L+ Sbjct: 9442 RDTTKTDSGLYRCVAFNEHGEIES-NVNLQVDERKKQEKIEGDLRAMLK-KTPILKKGAG 9499 Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMH-LVDGGNLV-----IQDARQTDAGRYQCIARNAA 186 + KN ++ +RM+ + D L+ ++ +++ + R + + Sbjct: 9500 EEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFELLKQSQEEETHRLEIEEIERS 9559 Query: 187 GTRESAIATLKIHIKPYL-----ITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRS 238 E L I+ L +T +D+ QT + F+ + + P++ Sbjct: 9560 ERDEKEFEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDAVFEIDIKIN-YPEIKLSWY 9618 Query: 239 AGGGNM-PLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294 G + P + ++ DG +LR+ N L D+G Y G AS LTV +P + Sbjct: 9619 KGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVC----GPHIASAKLTVIEP-A 9673 Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354 V ++ G TC + P W G I R H T V V Sbjct: 9674 WERHLQDVTLKEGQTCTMTCQFSV-PNVKSEWFRNGR---ILKPQGR---HKTEVEHKVH 9726 Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414 LTI D D + C + S+ +R + P T N + Sbjct: 9727 KLTIADVRAED-QGQYTCKYEDLETSAELR--------IEAEPIQFTKRIQNIVVSEHQS 9777 Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVA 469 A F C + + I+ WY L ++ + N NDG + + ++ D G Y+ +A Sbjct: 9778 ATFECE-VSFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIA 9834 Score = 52.8 bits (121), Expect = 5e-05 Identities = 44/129 (34%), Positives = 55/129 (42%), Gaps = 14/129 (10%) Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE-- 541 + P P+ F A D + P PP P + T SV L+W G S ILGY VE Sbjct: 18021 IGDPSPPSKPVF-AKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQ 18079 Query: 542 -VFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600 V E N+TP + +T Y V L G TY F V N+ G S P+ Sbjct: 18080 KVGDEEWRRANHTPES----------CPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAH 18129 Query: 601 VSDSVTVGD 609 V + V V D Sbjct: 18130 VPEPVLVKD 18138 Score = 52.8 bits (121), Expect = 5e-05 Identities = 70/320 (21%), Positives = 117/320 (36%), Gaps = 33/320 (10%) Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352 PS+ L N+ ++++G + GRP P + W +G +R TA Sbjct: 25239 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEP---LKQTTRVNVEETATS-- 25293 Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412 TVL I + +K+D V +A N AG++ + V P + + + Sbjct: 25294 -TVLHIKEGNKDDFGKYTV-TATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVI 25351 Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472 S T C I + + T+ + L + A +R Sbjct: 25352 SWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENR 25411 Query: 473 HGKY--VWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530 +GK + S A++V P PGPP P +++ + + W + Sbjct: 25412 YGKSAPLDSKAVIVQYPFKE-------------PGPPGTPFVTSISKDQMLVQWHEPVND 25458 Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMFIVRT 589 G + I+GY +E +NS WV + + + T + L G+ Y F V Sbjct: 25459 GGTKIIGYHLE----------QKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSA 25508 Query: 590 ENSHGLSGPSPVSDSVTVGD 609 EN G+ PS VS+ D Sbjct: 25509 ENIVGIGKPSKVSECFVARD 25528 Score = 52.4 bits (120), Expect = 7e-05 Identities = 36/129 (27%), Positives = 57/129 (44%), Gaps = 7/129 (5%) Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA---GGGNMPLGRVKVLDD-GSLRLDNVIL 264 + VV GS+ TF+ + G P+P+V W R +P ++ D L + V Sbjct: 13 QSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTK 72 Query: 265 ADEGEYSCEAENSVGAVSASGYLTV---YDPPSINLSPNSVNVESGNVARFTCTATGRPE 321 A+ G YS +A N G +++ L V PP+ S+ V G+ R TG P Sbjct: 73 ANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPT 132 Query: 322 PTMFWSVEG 330 P + + +G Sbjct: 133 PVVKFYRDG 141 Score = 52.4 bits (120), Expect = 7e-05 Identities = 34/108 (31%), Positives = 50/108 (46%), Gaps = 10/108 (9%) Query: 496 RAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPR 555 RA D LP PP+KP + T++T++W + G + I GY VE + + + Sbjct: 27003 RAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQ 27062 Query: 556 NSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603 + RG T Y + L G Y+F V++ N G S PS SD Sbjct: 27063 SLRG----------TEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSD 27100 Score = 52.0 bits (119), Expect = 1e-04 Identities = 51/198 (25%), Positives = 77/198 (38%), Gaps = 10/198 (5%) Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDG--DSRMHLVDG-GNLVIQDARQTDAGR 177 +G T E G P P V W ++GQ + ++ DG L I + ++GR Sbjct: 19 EGSTATFEA-HISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGR 77 Query: 178 YQCIARNAAGTRESAIATL-KIHIKP-YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235 Y A N +G S L K P + + + + GS V Q RV G P P V + Sbjct: 78 YSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKF 137 Query: 236 RRSAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292 R L ++ +G SL + D G YS A NSVG +++ L V Sbjct: 138 YRDGAEIQSSLD-FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGE 196 Query: 293 PSINLSPNSVNVESGNVA 310 + V + ++ Sbjct: 197 EEVPAKKTKTIVSTAQIS 214 Score = 52.0 bits (119), Expect = 1e-04 Identities = 103/442 (23%), Positives = 168/442 (38%), Gaps = 42/442 (9%) Query: 38 SPSPAIR-WYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96 SPS AI W K G + + G L ++ SDAG Y C ++ Sbjct: 12070 SPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQL-SDAGEYTC-VLRLGNKEKT 12127 Query: 97 RNATLHVAVLREEF-RLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155 A L V L F + E +G + L C + E +V W+K+G+ ++ Sbjct: 12128 STAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSC---ELNKERDVVWRKDGKIVVEKPGR 12184 Query: 156 RMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVA 213 + V G L I DA TDAG Y NA S+ + I+ +L+ D Sbjct: 12185 IVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKPIRDQHV 12244 Query: 214 QTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDGS---LRLDNVILADEGE 269 + + F C + D P++ W + P + ++L DG+ L++ N + D E Sbjct: 12245 KPKGTAIFACDIAKD-TPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAE 12303 Query: 270 YSCEAENSVGAVSASGYLTVYDPPSINLSP-NSVNVESGNVARFTCTATGRPEPTMFWSV 328 Y+ E E LT+ + L P V + A F + P W + Sbjct: 12304 YAVEIEGK----RYPAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQ-WKL 12358 Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT 388 +G ++ P + + G LT+ K D ++ A+N + LT Sbjct: 12359 KGE--LLRPSPTCE----IKAEGGKRFLTLRKV-KLDQAGEVLYQALN----AITTAILT 12407 Query: 389 VTSDD-DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT 447 V + D P+ + T+P + A F C + T E + W + + + + ++ Sbjct: 12408 VKEIELDFAVPL-----KDVTVPERRQARFEC--VLTREANVIWSKGPDIIKSSDKFDII 12460 Query: 448 NDG---TLVLKDLDKSDSGTYT 466 DG LV+ D D G YT Sbjct: 12461 ADGKKHILVINDSQFDDEGVYT 12482 Score = 52.0 bits (119), Expect = 1e-04 Identities = 83/351 (23%), Positives = 137/351 (39%), Gaps = 51/351 (14%) Query: 269 EYSCEAENSVGAVSA----SGYLTVYDP---PSINLS---PNSVNVESGNVARFTCTATG 318 E+ A+N+ GA+S S +T D P I + ++V +++G R +G Sbjct: 22355 EFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSG 22414 Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378 RP PTM WS +G G ++ + + D T L D+ + DS +A N Sbjct: 22415 RPPPTMEWSKDGKE---LEGTAKLEIK---IADFSTNLVNKDSTRRDS-GAYTLTATNPG 22467 Query: 379 GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY---FEG 435 G F + V D PP GP +AV T + + + +++W+ +G Sbjct: 22468 G--FAKHIFNVKVLDRPGPP---EGP---------LAV---TEVTSEKCVLSWFPPLDDG 22510 Query: 436 EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG-KYVWSGALLVDSPINPNIHF 494 A I ++ L ++ T V G +Y++ + + + Sbjct: 22511 GAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLES 22570 Query: 495 FRAADVSSL--PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNN 552 V+ P PP P +T S+ + W + G S I+ Y VE R +G Sbjct: 22571 EPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVE---RRDKAGQR 22627 Query: 553 TPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602 W+ ++ + Y V L G Y F + EN+ G+S PSP S Sbjct: 22628 -------WIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTS 22671 Score = 52.0 bits (119), Expect = 1e-04 Identities = 49/176 (27%), Positives = 74/176 (42%), Gaps = 30/176 (17%) Query: 425 PEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481 P P + W+ + L Q R N N+ L +KD + D G Y ++ G+ + + Sbjct: 23102 PTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLN 23161 Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSILGYQV 540 ++V PGPPT P+ + VT S+TLSW G SSI Y V Sbjct: 23162 VIV----------------LDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIV 23205 Query: 541 EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596 E R+T ++ W +++ V +T L G Y F + EN +G S Sbjct: 23206 E--KRDT--------STTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKS 23251 Score = 51.6 bits (118), Expect = 1e-04 Identities = 34/110 (30%), Positives = 45/110 (40%), Gaps = 9/110 (8%) Query: 500 VSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRG 559 V PGPP + ++ TSV W G S I+ Y TL + + Sbjct: 15725 VLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINY--------TLEKKDKTKPDSE 15776 Query: 560 WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 W+V+ + Y V LI G Y+F VR EN G GP VS + D Sbjct: 15777 WIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFG-PGPPCVSKPLVAKD 15825 Score = 51.6 bits (118), Expect = 1e-04 Identities = 52/192 (27%), Positives = 74/192 (38%), Gaps = 14/192 (7%) Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 PP L + G RF T T PEP + W G + I PG DK + Sbjct: 32616 PPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQK--IKPG-DNDKKYTFESDK 32672 Query: 352 GVTVLTIND-TDKNDSRNTIVCSAVNYAGSSFVRGKLTVT----SDDDRPPPIITNGPSN 406 G+ LTIN T +D+ T+V A N G + KLTVT D P+ +N Sbjct: 32673 GLYQLTINSVTTDDDAEYTVV--ARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLAN 32730 Query: 407 QTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG----TLVLKDLDKSDS 462 F P P + W +G+ L + ++G L ++D D+ Sbjct: 32731 AECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDT 32790 Query: 463 GTYTCVASSRHG 474 G Y A++ G Sbjct: 32791 GYYRVTATNTAG 32802 Score = 51.2 bits (117), Expect = 2e-04 Identities = 30/99 (30%), Positives = 47/99 (47%), Gaps = 3/99 (3%) Query: 391 SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG 450 S+ + PI SN + + +A T I P+P I W+F G L + DG Sbjct: 3496 SEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDG 3555 Query: 451 ---TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486 +L++ D G YTC+AS+ +GK + S L ++S Sbjct: 3556 DDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINS 3594 Score = 50.8 bits (116), Expect = 2e-04 Identities = 74/318 (23%), Positives = 120/318 (37%), Gaps = 36/318 (11%) Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361 + V++G T TG+PEP + W+ +I + +DK + +TI D+ Sbjct: 14627 LTVKAGTKIELPATVTGKPEPKITWT---KADMI---LKQDKRITIENVPKKSTVTIVDS 14680 Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421 ++D+ T + AVN G + ++ V P +N++ + + Sbjct: 14681 KRSDT-GTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESC----LLTWNPPR 14735 Query: 422 ICTPEPIIAWYFEGEALIQN--HRRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGKYVW 478 I + E A H+ + T D L + + A + +G Sbjct: 14736 DDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGV--- 14792 Query: 479 SGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGY 538 G + SPI F PGPPT+ ++T +VTL+W + + G S I GY Sbjct: 14793 -GEPVQASPITAKYQF-------DPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGY 14844 Query: 539 QVEVFSRETLSGNNTPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSG 597 VE +T WV + V T Y VK L Y F V EN G Sbjct: 14845 WVERLDPDT----------DKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGK 14894 Query: 598 PSPVSDSVTVGDDSNSLW 615 PS ++ + + D + W Sbjct: 14895 PSKSTEPILIKDPIDPPW 14912 Score = 50.8 bits (116), Expect = 2e-04 Identities = 97/407 (23%), Positives = 161/407 (39%), Gaps = 63/407 (15%) Query: 425 PEPIIAWYFEGEALIQNH--RRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481 P+P I+W +G L ++ R + T N TL +K+ K G YT + + + Sbjct: 28518 PKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPIT 28577 Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSILGYQV 540 ++ P P P PI + + SV LSW G I Y + Sbjct: 28578 VITLGP----------------PSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSI 28621 Query: 541 EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600 E RET N W ++ V +T + V +L+ Y F VR EN +G+S P Sbjct: 28622 E--KRETSQTN--------WKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVS--QP 28669 Query: 601 VSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYY 660 + S+ V + G Y N+ +D + +A D + E+ F+ Sbjct: 28670 LVSSIIVAKHQFRIPGPPG--KPVIY--NVTSDGMSLTWDAPVYDGGS-----EVTGFHV 28720 Query: 661 LEGLFIYFRPLDNITIEYEMKTILHSNDVSG--FEITSLRKYTKYEFFLIPFYKKFEGKP 718 + +I ++ ++++ +SG + T L + Y+F + + + G Sbjct: 28721 --------EKKERNSILWQK---VNTSPISGREYRATGLVEGLDYQFRV--YAENSAGLS 28767 Query: 719 SNSRVAQ-TLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVP 777 S S ++ TL P PP + + T+ LKW+PP L+ I GY++ Sbjct: 28768 SPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPP-LRDGGSKIVGYSIEKR----Q 28822 Query: 778 ANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIG-LGPFSQ 823 N+ V N T +T L+ G Y +I A +G + P SQ Sbjct: 28823 GNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQ 28869 Score = 50.0 bits (114), Expect = 4e-04 Identities = 38/109 (34%), Positives = 47/109 (43%), Gaps = 11/109 (10%) Query: 501 SSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGW 560 S P PP K +VT SV+LSW + G S ILGY VE+ + S W Sbjct: 22973 SERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEM----------QTKGSDKW 23022 Query: 561 VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 A V T + LI G Y F V +N G+S P +S V D Sbjct: 23023 ATCA-TVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKD 23070 Score = 50.0 bits (114), Expect = 4e-04 Identities = 80/346 (23%), Positives = 137/346 (39%), Gaps = 41/346 (11%) Query: 269 EYSCEAENSVGAVS----ASGYLTVYDP---PSINLSP---NSVNVESGNVARFTCTATG 318 E+ A+N+ GA+S ++G +T D P I++ P +++ V +G R G Sbjct: 24519 EFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHG 24578 Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378 +P PT+ W + G++ I +R + T D +L + D + D I+ A N A Sbjct: 24579 KPLPTIEW-LRGDKEI--EESARCEIKNT---DFKALLIVKDAIRIDGGQYIL-RASNVA 24631 Query: 379 GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438 GS + V DRP GP + + + C+ +P P+ + Sbjct: 24632 GSKSFPVNVKVL---DRP------GPPEGPVQVTGVTSEKCSLTWSP-PLQDGGSDISHY 24681 Query: 439 IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS-GALLVDSPINPNIHFFRA 497 + R T+V ++ + + + + + + V P+ + Sbjct: 24682 VVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKN 24741 Query: 498 ADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNS 557 V LPGPP N+ S+T+ W++ + G S I+GY VE R+ Sbjct: 24742 PFV--LPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVE----------KRDRSG 24789 Query: 558 RGWVVI-ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602 W+ RR+ V L Y F V EN+ G+ PSP + Sbjct: 24790 IRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPAT 24835 Score = 49.6 bits (113), Expect = 5e-04 Identities = 35/117 (29%), Positives = 48/117 (41%), Gaps = 11/117 (9%) Query: 494 FFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNT 553 F + AD P PP + + T +SV L W K G S ILGY +E Sbjct: 14209 FVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIE----------RC 14258 Query: 554 PRNSRGWV-VIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 W+ + V + Y V L G Y++ V EN G+S PS + +T D Sbjct: 14259 EEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADD 14315 Score = 49.6 bits (113), Expect = 5e-04 Identities = 59/242 (24%), Positives = 89/242 (36%), Gaps = 23/242 (9%) Query: 374 AVNYAGSSF---VRGKLTVTSDDDRPPPIITNGPSNQTL-PIKSMAVFPCTAICTPEPII 429 AVN AG S G++ T + P I G + + S P P P Sbjct: 16710 AVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKS 16769 Query: 430 AWYFEGEA--LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 +W F+G+A +++ ++ D L + + S S GKY ++ + Sbjct: 16770 SWEFDGKAKKAMKDGVHDIPEDAQL--ETAENSSVIIIPECKRSHTGKY----SITAKNK 16823 Query: 488 INPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRET 547 R V +PGPP ++T S LSW + G I GY +E + T Sbjct: 16824 AGQKTANCRVK-VMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIE---KRT 16879 Query: 548 LSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607 + G + W + T +VV L+ Y F VR EN G+ P T Sbjct: 16880 IDG-------KAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTA 16932 Query: 608 GD 609 D Sbjct: 16933 RD 16934 Score = 49.6 bits (113), Expect = 5e-04 Identities = 32/108 (29%), Positives = 49/108 (45%), Gaps = 11/108 (10%) Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562 +PGPP P+ + S+ + W++ G S ++GY +E RNS WV Sbjct: 23267 VPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLE----------RKERNSILWVK 23316 Query: 563 IARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 + + + QT + L G+ Y F V EN G+ PS VS+ D Sbjct: 23317 LNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARD 23364 Score = 49.2 bits (112), Expect = 7e-04 Identities = 31/90 (34%), Positives = 39/90 (43%), Gaps = 4/90 (4%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGGGNMPLGRVKVLDDGSL 257 PY IT P G SV F C+VGG+P P V W++S G + K + L Sbjct: 1082 PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKL 1141 Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYL 287 + D GEY+ N G SAS L Sbjct: 1142 VISMTFADDAGEYTIVVRNKHGETSASASL 1171 Score = 49.2 bits (112), Expect = 7e-04 Identities = 52/179 (29%), Positives = 71/179 (39%), Gaps = 32/179 (17%) Query: 425 PEPIIAWYF-EGEALIQNHR--RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481 P P W E E + +H + L++KD+ + DSG Y+ A + G Sbjct: 19853 PHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIK 19912 Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDT-SVTLSWSQNNKIGSSSILGYQV 540 ++ V PGPP P + D + +LSW + G S+I Y V Sbjct: 19913 VV----------------VMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIV 19956 Query: 541 EVFSRETLSGNNTPRNSRG-WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598 E SRG WV V +T V LIPG Y+F VR EN G+S P Sbjct: 19957 EKCD-----------VSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEP 20004 Score = 49.2 bits (112), Expect = 7e-04 Identities = 97/385 (25%), Positives = 146/385 (37%), Gaps = 41/385 (10%) Query: 178 YQCIARNAAG-----TRESAIATLKIHIKPYLIT-GP---EDVVAQTGSSVTFQCRVGGD 228 ++ IARNAAG + + T + + P I+ P + +V G S + G Sbjct: 23438 FRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGK 23497 Query: 229 PLPDVLWRRSAGG-GNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGY 286 P+P + W + N +K D SL + + + D G Y +A+N G S + Sbjct: 23498 PIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVN 23557 Query: 287 LTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR---DK 343 + V D P P V SG A CT +P P +G II + R + Sbjct: 23558 VKVLDRPG---PPEGPVVISGVTAE-KCTLAWKP-PLQ----DGGSDIINYIVERRETSR 23608 Query: 344 YHATAVFDGVTVLTINDTDKNDSRN-TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN 402 T V V L+ T + T AVN G V + + P Sbjct: 23609 LVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPK 23668 Query: 403 GPSNQTLPIKSM-AVFPCTAICTPEPIIAWYF-----EGEALIQNHRRNVTNDGTLVLKD 456 P T+ SM V+ A I+ + EG + H+R + G L L+ Sbjct: 23669 APEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLI---GELRLRV 23725 Query: 457 LDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVT 516 ++ Y S+ + A + P P+ + +A D PGPP P ++T Sbjct: 23726 TGLIENHDYEFRVSAEN-------AAGLSEPSPPSA-YQKACDPIYKPGPPNNPKVIDIT 23777 Query: 517 DTSVTLSWSQNNKIGSSSILGYQVE 541 +SV LSWS+ G I GY VE Sbjct: 23778 RSSVFLSWSKPIYDGGCEIQGYIVE 23802 Score = 48.8 bits (111), Expect = 9e-04 Identities = 64/264 (24%), Positives = 102/264 (38%), Gaps = 33/264 (12%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 DVTV + A C + + W KG ++ S I+ A G + + D Sbjct: 12421 DVTVPERRQARFECVLTREAN--VIWSKGPDIIKSSDKFDII-ADGKKHILVINDSQFDD 12477 Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139 GVY E +AR L V +R +F E + +G+T C + + Sbjct: 12478 EGVYTAEVEGKKTSAR-----LFVTGIRLKFMSPLEDQTVKEGETATFVC--ELSHEKMH 12530 Query: 140 VYWKKN------GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193 V W KN +T+L + + H ++ + + D Q A + S+ Sbjct: 12531 VVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKEL----------SST 12580 Query: 194 ATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL 252 A LK+ PY D A +T +C V D +P V W + G +P + + Sbjct: 12581 AQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKD-VP-VKWFKD-GEEIVPSPKYSIK 12637 Query: 253 DDGS---LRLDNVILADEGEYSCE 273 DG L++ L D+GEY C+ Sbjct: 12638 ADGLRRILKIKKADLKDKGEYVCD 12661 Score = 48.8 bits (111), Expect = 9e-04 Identities = 86/376 (22%), Positives = 146/376 (38%), Gaps = 62/376 (16%) Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD------PPSINLSPNSVNV 304 V+ D SL + + + ++ A N+VG VY+ PP I L P + + Sbjct: 19779 VVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKI-LMPEQITI 19837 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 ++G R G+P PT W +G ++ + A D ++L I D + Sbjct: 19838 KAGKKLRIEAHVYGKPHPTCKWK-KGEDEVV-----TSSHLAVHKADSSSILIIKDVTRK 19891 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424 DS +A N +G+ + K+ V D P GP I + C+ Sbjct: 19892 DS-GYYSLTAENSSGTDTQKIKVVVM---DAP------GPPQPPFDISDIDADACS---- 19937 Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS-----SRHGKYV-- 477 ++W+ +++ N+TN +++ D S T +AS R GK + Sbjct: 19938 ----LSWHIP----LEDGGSNITN---YIVEKCDVSRGDWVTALASVTKTSCRVGKLIPG 19986 Query: 478 --WSGALLVDSPINPNIHFFRAADVSSLP-GPPTKPITHNVTDTS---VTLSWSQNNKIG 531 + + ++ + V+ P G P++P VT + + ++W + + G Sbjct: 19987 QEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDG 20046 Query: 532 SSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMFIVRTE 590 S I+GY +E RNS WV V T Y L+ G+ Y F + Sbjct: 20047 GSPIIGYLIE----------RKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYAL 20096 Query: 591 NSHGLSGPSPVSDSVT 606 N G S PS ++ VT Sbjct: 20097 NKAGSSPPSKPTEYVT 20112 Score = 48.8 bits (111), Expect = 9e-04 Identities = 34/108 (31%), Positives = 49/108 (45%), Gaps = 11/108 (10%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV-V 562 PG P KP VT S ++W G + I Y +E RE + W+ V Sbjct: 31752 PGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLE--KRE--------KKQNKWISV 31801 Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDD 610 + +T + VK+LI G+ Y F V+ EN G S S +S+ +T D Sbjct: 31802 TTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSD 31849 Score = 48.4 bits (110), Expect = 0.001 Identities = 39/114 (34%), Positives = 53/114 (46%), Gaps = 12/114 (10%) Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556 A D P P KPI +VT S+ + W++ GS ILGY +E RE N Sbjct: 15823 AKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSP-ILGYWLE--KREV--------N 15871 Query: 557 SRGWVVIARRV-HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 S W + + + + V L+ G+TY+F V EN+ G SP SD T D Sbjct: 15872 STHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHD 15925 Score = 47.6 bits (108), Expect = 0.002 Identities = 34/97 (35%), Positives = 50/97 (51%), Gaps = 6/97 (6%) Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL---VDGGNLVIQDARQTDAGRY 178 G+T VLE RG P P+V W K+G+ L + +RM + + LV++D +TD G+Y Sbjct: 25649 GETFVLEA-DIRGKPIPDVVWSKDGKE-LEETAARMEIKSTIQKTTLVVKDCIRTDGGQY 25706 Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT 215 N GT+ I T+K+ +P GP V T Sbjct: 25707 ILKLSNVGGTKSIPI-TVKVLDRPGPPEGPLKVTGVT 25742 Score = 47.2 bits (107), Expect = 0.003 Identities = 54/218 (24%), Positives = 82/218 (37%), Gaps = 27/218 (12%) Query: 4 DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63 D G P I++ + ++ ATL+ G P P I+W+ GVL+ + Sbjct: 3495 DSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFD 3554 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTA-------------RSRNATLHVAVLRE-- 108 G L ++ D G Y C A+N YG ++ AV + Sbjct: 3555 GDDHSLIILFTKL-EDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLE 3613 Query: 109 --------EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHL 159 F E + + AQG + E G P P V W K+N Q + +H Sbjct: 3614 KLGGPCPPHFLKELKPIRCAQGLPAIFE-YTVVGEPAPTVTWFKENKQLCTSVYYTIIHN 3672 Query: 160 VDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196 +G G ++ D ++ D+G Y C A N G A L Sbjct: 3673 PNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELL 3710 Score = 47.2 bits (107), Expect = 0.003 Identities = 32/109 (29%), Positives = 54/109 (49%), Gaps = 15/109 (13%) Query: 506 PPTKPITHNVTDTS---VTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV- 561 PP+ P+ +VTD + ++W K G S I+GY VE+ P + W+ Sbjct: 15211 PPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEM----------CPVGTEKWMR 15260 Query: 562 VIARRVHQTHY-VVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 V +R + + V + ++P Y+ VR N+ G+S PS +S++V D Sbjct: 15261 VNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKD 15309 Score = 47.2 bits (107), Expect = 0.003 Identities = 45/169 (26%), Positives = 68/169 (40%), Gaps = 18/169 (10%) Query: 444 RNVTNDGTLVLKDLDKSDSGTYTCVASSRH---GKYVWSGALLVDSPINPNIHFFRAADV 500 R V D + +D D+ + + +S GKY +L + +P F V Sbjct: 19568 RKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKY----SLTLVNPAGEKAVFVNVR-V 19622 Query: 501 SSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGW 560 PGP + +VT TS +SW+ G S + Y VE RE + + W Sbjct: 19623 LDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVE--KREA--------DRKTW 19672 Query: 561 VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 + V +T + V +L+PG Y F V N +G P+ V V D Sbjct: 19673 STVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASD 19721 Score = 47.2 bits (107), Expect = 0.003 Identities = 61/260 (23%), Positives = 101/260 (38%), Gaps = 36/260 (13%) Query: 357 TINDTDKNDSRNTIVCSAVNYAG---SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413 T+ +N N +C A+N G + + G + V + PP I + + + +++ Sbjct: 25991 TVTKLKENTEYNFRIC-AINSEGVGEPATLPGSV-VAQERIEPPEIELDADLRKVVVLRA 26048 Query: 414 MAVFPC--TAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVAS 470 A T PEP + W L + VT+ T LV+ ++ + DSG Y Sbjct: 26049 SATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLE 26108 Query: 471 SRHG-KYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529 + G K + ++DSP P V SVTLSW Sbjct: 26109 NNSGSKTAFVNVRVLDSP-----------------SAPVNLTIREVKKDSVTLSWEPPLI 26151 Query: 530 IGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRT 589 G + I Y VE RET + + I +T + +++L G +Y F V Sbjct: 26152 DGGAKITNYIVE--KRET--------TRKAYATITNNCTKTTFRIENLQEGCSYYFRVLA 26201 Query: 590 ENSHGLSGPSPVSDSVTVGD 609 N +G+ P+ ++ V V + Sbjct: 26202 SNEYGIGLPAETTEPVKVSE 26221 Score = 47.2 bits (107), Expect = 0.003 Identities = 38/124 (30%), Positives = 54/124 (43%), Gaps = 7/124 (5%) Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352 P I V S +VA+F ATG P PT W+ +G + I G KY + G Sbjct: 33779 PVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDG-KAITQGG----KYKLSEDKGG 33833 Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412 L I+ TD +DS C+ N AGS KLT+ + D ++ +++ P K Sbjct: 33834 F-FLEIHKTDTSDS-GLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQK 33891 Query: 413 SMAV 416 V Sbjct: 33892 KAVV 33895 Score = 46.8 bits (106), Expect = 0.004 Identities = 45/162 (27%), Positives = 67/162 (41%), Gaps = 14/162 (8%) Query: 39 PSPAIRWYKGGVLVV---SDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTAR 95 P P + WYK G + +D + GL+ L DA Y A N YG Sbjct: 32644 PEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDA-EYTVVARNKYGEDS 32702 Query: 96 SR---NATLHV----AVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148 + TLH + LR F+ + + +G +V E + G P P + W+K+GQ Sbjct: 32703 CKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFE-IRVSGIPPPTLKWEKDGQP 32761 Query: 149 LLFDGDSRM--HLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188 L + + +D L I+D D G Y+ A N AG+ Sbjct: 32762 LSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGS 32803 Score = 46.8 bits (106), Expect = 0.004 Identities = 30/103 (29%), Positives = 44/103 (42%), Gaps = 4/103 (3%) Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249 +S +K + ++T P + G S F C G+P+P V W R G R Sbjct: 33476 KSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRK-GQVLSTSARH 33534 Query: 250 KVLD---DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 +V + + +V +DEG YS ENS G A LT+ Sbjct: 33535 QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTI 33577 Score = 46.4 bits (105), Expect = 0.005 Identities = 54/219 (24%), Positives = 92/219 (42%), Gaps = 12/219 (5%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 +AP + V V AT G P P + W++ G ++ + T + + Sbjct: 4 QAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63 Query: 70 RATHGRV-HSDAGVYWCEATNSYGTARSRNATLHVA-VLREEFRLEPESKQSAQGDTVVL 127 + T V +++G Y +ATN G A S L A F +S QG V L Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRL 123 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAA 186 + + G P P V + ++G + D ++ D +L+I +A D+G Y A N+ Sbjct: 124 Q-VRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSV 182 Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV 225 G R ++ A L L+ G E+V A+ ++ ++ Sbjct: 183 G-RATSTAEL-------LVQGEEEVPAKKTKTIVSTAQI 213 Score = 46.4 bits (105), Expect = 0.005 Identities = 36/116 (31%), Positives = 53/116 (45%), Gaps = 13/116 (11%) Query: 496 RAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPR 555 +A D +P P +PI VT S ++W++ + G I Y +E RET+S Sbjct: 17931 KAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHD-GGKPITNYILE--KRETMS------ 17981 Query: 556 NSRGWVVIARR-VHQ-THYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 + W + + +H T + V L+ G Y F V EN G+ PSP S V D Sbjct: 17982 --KRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKD 18035 Score = 46.4 bits (105), Expect = 0.005 Identities = 34/110 (30%), Positives = 50/110 (45%), Gaps = 11/110 (10%) Query: 500 VSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRG 559 V+ +P PP K +VT SV+LSW++ G S I+ Y VE+ ++S Sbjct: 24054 VAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEM----------QAKHSEK 24103 Query: 560 WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 W A RV V+ +L G Y+F V N G S P ++ + D Sbjct: 24104 WSECA-RVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKD 24152 Score = 46.0 bits (104), Expect = 0.006 Identities = 32/102 (31%), Positives = 43/102 (42%), Gaps = 3/102 (2%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P ++ +VTV + TL C G PSP + WY+ + S I G+ L Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 1002 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE 113 D+G + C A N GT S + L V V EEF E Sbjct: 1003 REA-FAEDSGRFTCSAVNEAGTV-STSCYLAVQV-SEEFEKE 1041 Score = 46.0 bits (104), Expect = 0.006 Identities = 51/177 (28%), Positives = 77/177 (43%), Gaps = 29/177 (16%) Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 PEP I W EG+ L++ R ++ ++DL + + V + HGKY+ S Sbjct: 18863 PEPDITWTKEGKVLVREKRVDL-------IQDLPRVELQIKEAVRAD-HGKYIISAK--- 18911 Query: 485 DSPINPNIHFFRAADVSSL--PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEV 542 N + H +A V+ L PGP NVT + T+SW G S I + VE Sbjct: 18912 ----NSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEY 18967 Query: 543 FSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599 P N +GW ++A V + + +L+ Y F V EN G+ GP+ Sbjct: 18968 ---------RKP-NQKGWSIVASDVTK-RLIKANLLANNEYYFRVCAENKVGV-GPT 19012 Score = 46.0 bits (104), Expect = 0.006 Identities = 33/106 (31%), Positives = 48/106 (45%), Gaps = 10/106 (9%) Query: 506 PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565 PP KP+ N+T +VTL W++ G I Y VE R+ +G N Sbjct: 22286 PPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVE--KRDLPNGRWLKAN-------FS 22336 Query: 566 RVHQTHYVVKSLIPGITYMFIVRTENSHG-LSGPSPVSDSVTVGDD 610 + + + V L Y F V +N+ G +S PS SD++T DD Sbjct: 22337 NILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDD 22382 Score = 45.6 bits (103), Expect = 0.008 Identities = 33/106 (31%), Positives = 43/106 (40%), Gaps = 10/106 (9%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 P PP N+T + L W+ K G S I Y VE R+ +GW + Sbjct: 15011 PSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVE--KRDV--------RRKGWQTV 15060 Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 V T V L G Y+F V EN+ G S + + DSV D Sbjct: 15061 DTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKD 15106 Score = 45.6 bits (103), Expect = 0.008 Identities = 63/250 (25%), Positives = 89/250 (35%), Gaps = 40/250 (16%) Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPS--NQTLPIKS--MAVFPCTAICTPEPII 429 AVN G S L V DD PP I S T+ +K+ P P P I Sbjct: 16298 AVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKI 16357 Query: 430 AWYFEGEALIQN--HRRNVTNDGT--------LVLKDLDKSDSGTYTCVASSRHGKYVWS 479 W + E +I+ +T + L + + D GTYT AS+R G Sbjct: 16358 EWS-KNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGS---- 16412 Query: 480 GALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQ 539 + N+H +V P PP ++ S L+W G S I Y Sbjct: 16413 --------VFRNVH----VEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYV 16460 Query: 540 VEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599 ++ + R W + + Y + LIP Y F VR N +G+S Sbjct: 16461 IDK--------RDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDEC 16512 Query: 600 PVSDSVTVGD 609 SD V + D Sbjct: 16513 K-SDKVVIQD 16521 Score = 45.6 bits (103), Expect = 0.008 Identities = 78/327 (23%), Positives = 130/327 (39%), Gaps = 32/327 (9%) Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556 A D PGPP+ P + T +S++L W K G S I GY VE+ T Sbjct: 16625 AGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEP 16684 Query: 557 SRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD--DSNSL 614 + + VV +L Y F V+ N G S PS + + D + + Sbjct: 16685 D-------KLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEV 16737 Query: 615 WEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNI 674 + G + + I +I+ P T K WE + + + +I Sbjct: 16738 FIDIGAQDCLVCKAGSQI-RIPAVIKGRP----TPKSSWE----FDGKAKKAMKDGVHDI 16788 Query: 675 TIEYEMKTILHSNDVSGFEITSLRKYT-KYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDG 733 + +++T +S+ + E R +T KY I K K +N RV + DVP G Sbjct: 16789 PEDAQLETAENSSVIIIPECK--RSHTGKYS---ITAKNKAGQKTANCRV--KVMDVP-G 16840 Query: 734 PPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT 793 PP ++++ + + L W P+ I GY + +D K+ +N +T Sbjct: 16841 PPKDLKVSDITRGSCRLSWKMPD-DDGGDRIKGYVIEKRTID---GKAWTKVNPDC-GST 16895 Query: 794 SLIMTNLTSGVSYSVQIAAETIIGLGP 820 + ++ +L S Y ++ AE G+GP Sbjct: 16896 TFVVPDLLSEQQYFFRVRAENRFGIGP 16922 Score = 45.2 bits (102), Expect = 0.011 Identities = 48/198 (24%), Positives = 82/198 (41%), Gaps = 16/198 (8%) Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGN--RTIIFPGMSRDKYHATAVF 350 P+ SV V G+ A F +G P P + W +G T PG+ + Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQ------ISFS 59 Query: 351 DGVTVLTINDTDK-NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409 DG LTI K N R ++ A N +G + +L V ++ PP + T+ Sbjct: 60 DGRAKLTIPAVTKANSGRYSL--KATNGSGQATSTAELLVKAET--APPNFVQRLQSMTV 115 Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYT 466 S P P++ +Y +G + + ++ +G +L++ + DSGTY+ Sbjct: 116 RQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175 Query: 467 CVASSRHGKYVWSGALLV 484 A++ G+ + LLV Sbjct: 176 VNATNSVGRATSTAELLV 193 Score = 45.2 bits (102), Expect = 0.011 Identities = 49/209 (23%), Positives = 81/209 (38%), Gaps = 31/209 (14%) Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359 ++ ++ G+VA + T G P+P + W G ++ + K+ VFDG I Sbjct: 3510 SNADISMGDVATLSVTVIGIPKPKIQWFFNG---VLLTPSADYKF----VFDGDDHSLII 3562 Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTS------DDDRPPPIITN-----GPS--- 405 K + C A N G + L + S D + + + GP Sbjct: 3563 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 3622 Query: 406 --NQTLPIKSM----AVFPCTAICTPEPIIAWYFEGEALIQNHR----RNVTNDGTLVLK 455 + PI+ A+F T + P P + W+ E + L + N GT ++ Sbjct: 3623 FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 3682 Query: 456 DLDKSDSGTYTCVASSRHGKYVWSGALLV 484 D + DSG Y C A + G+ + LLV Sbjct: 3683 DPQREDSGLYICKAENMLGESTCAAELLV 3711 Score = 45.2 bits (102), Expect = 0.011 Identities = 36/111 (32%), Positives = 47/111 (42%), Gaps = 4/111 (3%) Query: 499 DVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558 D LPGPP KP T S+ +SW+ G S I GY +E RE R SR Sbjct: 16521 DPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLE--KREE-GSPYWSRVSR 16577 Query: 559 GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 + + + V L+ G+ Y F N+ G+ PS SD GD Sbjct: 16578 A-PITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGD 16627 Score = 45.2 bits (102), Expect = 0.011 Identities = 34/126 (26%), Positives = 55/126 (43%), Gaps = 6/126 (4%) Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD---GSLRLDN 261 +T + + + G ++ RV G P PD+ W + G + RV ++ D L++ Sbjct: 18839 VTCRDVITVRVGQTIRILARVKGRPEPDITWTKE-GKVLVREKRVDLIQDLPRVELQIKE 18897 Query: 262 VILADEGEYSCEAENSVGAVSASGYLTVYDPPS--INLSPNSVNVESGNVARFTCTATGR 319 + AD G+Y A+NS G S + V D P NL +V E+ ++ G Sbjct: 18898 AVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGG 18957 Query: 320 PEPTMF 325 E T F Sbjct: 18958 SEITNF 18963 Score = 45.2 bits (102), Expect = 0.011 Identities = 36/136 (26%), Positives = 57/136 (41%), Gaps = 6/136 (4%) Query: 164 NLVIQDARQTDAGRYQCIARNAAGT---RES-AIATLKIHIKPYLITGPEDVVAQTGSSV 219 +LV+ ++ +++ ARNA G RE+ + K + P I PE + + G + Sbjct: 19784 SLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKL 19843 Query: 220 TFQCRVGGDPLPDVLWRRSAGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENS 277 + V G P P W++ + L K L + +V D G YS AENS Sbjct: 19844 RIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENS 19903 Query: 278 VGAVSASGYLTVYDPP 293 G + + V D P Sbjct: 19904 SGTDTQKIKVVVMDAP 19919 Score = 45.2 bits (102), Expect = 0.011 Identities = 32/107 (29%), Positives = 51/107 (47%), Gaps = 12/107 (11%) Query: 506 PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565 PP KP N+T SVTL W++ G + GY VE + P S+ W+ Sbjct: 21203 PPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVE--------KRDLP--SKSWMKANH 21252 Query: 566 -RVHQTHYVVKSLIPGITYMFIVRTENSHG-LSGPSPVSDSVTVGDD 610 V + + V L+ G Y F +R +N+ G +S PS ++++ D+ Sbjct: 21253 VNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDE 21299 Score = 45.2 bits (102), Expect = 0.011 Identities = 30/115 (26%), Positives = 49/115 (42%), Gaps = 12/115 (10%) Query: 489 NPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETL 548 +P F++A D PGPP P + + +S++++W++ G S I GY VE+ E Sbjct: 22668 SPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPE-- 22725 Query: 549 SGNNTPRNSRGWVVIA--RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPV 601 W ++ + T Y + L Y + NS GL P+ V Sbjct: 22726 --------EDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALV 22772 Score = 45.2 bits (102), Expect = 0.011 Identities = 38/137 (27%), Positives = 60/137 (43%), Gaps = 11/137 (8%) Query: 174 DAGRYQCIARNAAGT------RESAIATLKIHIKPYLITGPE---DVVAQTGSSVTFQCR 224 D ++ IARNA GT I T ++ P + GPE ++ ++G S+ + Sbjct: 28849 DRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKAL 28908 Query: 225 VGGDPLPDVLWRRSAGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVS 282 V G P+P V W + M + VL SL + + G Y+ EA+N+ G+ Sbjct: 28909 VQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAK 28968 Query: 283 ASGYLTVYDPPSINLSP 299 A + V D P + P Sbjct: 28969 AEIKVKVQDTPGKVVGP 28985 Score = 44.8 bits (101), Expect = 0.015 Identities = 30/79 (37%), Positives = 40/79 (50%), Gaps = 7/79 (8%) Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---RVKVLDDG--SLRLDNVILADEGEY 270 G VTF C++ G PLP + W + G + G ++ L DG SLR+ V+ DEG Y Sbjct: 1305 GMGVTFHCKMSGYPLPKIAWYKD--GKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIY 1362 Query: 271 SCEAENSVGAVSASGYLTV 289 + A N G SG L V Sbjct: 1363 TAFASNIKGNAICSGKLYV 1381 Score = 44.8 bits (101), Expect = 0.015 Identities = 21/54 (38%), Positives = 30/54 (55%) Query: 489 NPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEV 542 +P +++A D PGPPT + T S+TL+W + G S ILGY VE+ Sbjct: 24832 SPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEI 24885 Score = 44.8 bits (101), Expect = 0.015 Identities = 31/99 (31%), Positives = 43/99 (43%), Gaps = 11/99 (11%) Query: 500 VSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRG 559 ++ P PP K +++ SV+L+W + G S I+ Y VE + + Sbjct: 27298 ITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALE----------KGQKN 27347 Query: 560 WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598 WV A TH+VV L Y F V EN GLS P Sbjct: 27348 WVKCA-VAKSTHHVVSGLRENSEYFFRVFAENQAGLSDP 27385 Score = 44.8 bits (101), Expect = 0.015 Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 3/80 (3%) Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVL 454 P+I G + T+ S+A F A P P W +G+A+ Q + ++ D L + Sbjct: 33779 PVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEI 33838 Query: 455 KDLDKSDSGTYTCVASSRHG 474 D SDSG YTC + G Sbjct: 33839 HKTDTSDSGLYTCTVKNSAG 33858 Score = 44.4 bits (100), Expect = 0.019 Identities = 32/109 (29%), Positives = 44/109 (40%), Gaps = 10/109 (9%) Query: 501 SSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGW 560 +++P PP + T S+ L+W G S I GY VE PR S W Sbjct: 14512 ATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVE----------RCPRGSDKW 14561 Query: 561 VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 V V +T V L G Y + V+ N G S PS ++ + D Sbjct: 14562 VACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVD 14610 Score = 44.4 bits (100), Expect = 0.019 Identities = 29/115 (25%), Positives = 46/115 (40%), Gaps = 10/115 (8%) Query: 495 FRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTP 554 F V P PP +T SV+++W G S I Y VE RE Sbjct: 23952 FVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVE--KREA------- 24002 Query: 555 RNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 + + + H+ + + L G +Y F V EN +G+ P+ +D + V + Sbjct: 24003 -TRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAE 24056 Score = 44.0 bits (99), Expect = 0.025 Identities = 36/104 (34%), Positives = 50/104 (48%), Gaps = 13/104 (12%) Query: 496 RAADVSSLPGPPTKPITH-NVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTP 554 +A D PGPP K + H +V T V+L W++ ++ G S I GY VE + E Sbjct: 18329 KALDPLHPPGPP-KDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVE-YQEE-------- 18378 Query: 555 RNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598 ++ W+ + V VV L G TY F V+ EN GL P Sbjct: 18379 -GTQDWIKF-KTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLP 18420 Score = 44.0 bits (99), Expect = 0.025 Identities = 33/112 (29%), Positives = 51/112 (45%), Gaps = 9/112 (8%) Query: 134 GSPEPNVYWKKNGQTLLFDG-DSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGTRE 190 G P+P V W + G+ ++ DG R+ GG L+I DA YQ A N G+ Sbjct: 31880 GHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGS-V 31938 Query: 191 SAIATLKIHIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 S A+L++ + P + G V A G V+ + G P P + W++ Sbjct: 31939 SGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQK 31990 Score = 43.6 bits (98), Expect = 0.034 Identities = 33/129 (25%), Positives = 58/129 (44%), Gaps = 4/129 (3%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL---VDGGNLV 166 F +P ++ +G +VV C G+P+P+VYWKK+G L ++ LV Sbjct: 1084 FITKPVVQKLVEGGSVVFGC-QVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLV 1142 Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVG 226 I DAG Y + RN G ++ + L+ L+ ++++ QT + Q Sbjct: 1143 ISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQTQVTAFVQEPKV 1202 Query: 227 GDPLPDVLW 235 G+ P ++ Sbjct: 1203 GETAPGFVY 1211 Score = 43.6 bits (98), Expect = 0.034 Identities = 56/215 (26%), Positives = 87/215 (40%), Gaps = 35/215 (16%) Query: 275 ENSVGAVSASGYLTV--YDPPSINLSPN-----------SVNVESGNVARFTCTATGRPE 321 E A++ G +T+ + P I LSP+ S V G+ A F G+P+ Sbjct: 2047 EEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPD 2106 Query: 322 PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381 P W G + D+ + D V L I D DS +I+ A+N AG + Sbjct: 2107 PECEWYKNGVKI-----ERSDRIYWYWPEDNVCELVIRDVTAEDSA-SIMVKAINIAGET 2160 Query: 382 FVRGKLTVTSDDDRPPPIITNGPSNQTLPIK---SMAVFPCTAICTPEPI--IAWYFEGE 436 L V + +IT Q + K +MA F C T EP + WY +G Sbjct: 2161 SSHAFLLVQAKQ-----LITFTQELQDVVAKEKDTMATFECE---TSEPFVKVKWYKDGM 2212 Query: 437 ALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCV 468 + + + + +D L + +D SD+ Y+CV Sbjct: 2213 EVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCV 2247 Score = 43.6 bits (98), Expect = 0.034 Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 5/93 (5%) Query: 731 PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH 790 P PP +E+ + T LKW+ PE ++G N +V DV K ++TTV Sbjct: 15010 PPSPPRWLEVINITKNTADLKWTVPE---KDGGSPITNYIVEKRDV-RRKGWQTVDTTV- 15064 Query: 791 QATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQ 823 + T +T LT G Y ++AAE IG +++ Sbjct: 15065 KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTE 15097 Score = 43.6 bits (98), Expect = 0.034 Identities = 75/327 (22%), Positives = 123/327 (37%), Gaps = 33/327 (10%) Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361 + ++G+ +GRP P + W +E R D+ T D T LT+ D+ Sbjct: 29584 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRL-----KETDRVSITTTKDRTT-LTVKDS 29637 Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421 + DS + + N AG + V RP P+ GP + + S++ C Sbjct: 29638 MRGDSGRYFL-TLENTAGVKTFSVTVVVIG---RPGPV--TGP----IEVSSVSAESCV- 29686 Query: 422 ICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS-G 480 + EP E I R + T LV + ++ + V S Sbjct: 29687 LSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSEN 29746 Query: 481 ALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQV 540 V P+ V P PT+P ++V+ ++++ W + G S I+GY V Sbjct: 29747 RFGVSKPLESAPIIAEHPFVP--PSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWV 29804 Query: 541 EVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599 E R T+ WV + + +Y V L+ G+ Y F N+ G+S S Sbjct: 29805 EKKERNTIL----------WVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKAS 29854 Query: 600 PVSDSVTVGD--DSNSLWEGTGVSNST 624 S + + D+ E T V+ ST Sbjct: 29855 EASRPIMAQNPVDAPGRPEVTDVTRST 29881 Score = 43.2 bits (97), Expect = 0.044 Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 6/97 (6%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 P PP K +T +V LSW G S + Y VE L+ + T W Sbjct: 16939 PDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVEC-----LAWDPTGTKKEAWRQC 16993 Query: 564 ARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599 +R V + + V+ L+ G Y F V+ N+ G+S PS Sbjct: 16994 NKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPS 17030 Score = 43.2 bits (97), Expect = 0.044 Identities = 36/113 (31%), Positives = 48/113 (42%), Gaps = 10/113 (8%) Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556 A D + PGPP +T + T +S L WS K G S + GY VE + E G Sbjct: 17342 ARDPIAPPGPPFPKVT-DWTKSSADLEWSPPLKDGGSKVTGYIVE-YKEE---GKEEWEK 17396 Query: 557 SRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 + + V T VV L G Y F V N G+ P V+D + + D Sbjct: 17397 GKD-----KEVRGTKLVVTGLKEGAFYKFRVSAVNIAGIGEPGEVTDVIEMKD 17444 Score = 43.2 bits (97), Expect = 0.044 Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 7/102 (6%) Query: 506 PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565 PP KP +VT ++V+L W++ G S I+GY VE L G+ R + Sbjct: 20119 PPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACK---LPGDKWVRCN----TAPH 20171 Query: 566 RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607 ++ Q Y L Y F + +S PS SD VT+ Sbjct: 20172 QIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTI 20213 Score = 43.2 bits (97), Expect = 0.044 Identities = 30/101 (29%), Positives = 45/101 (44%), Gaps = 3/101 (2%) Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQC 180 GD + +E +P G P+P V WKK Q L ++ I + ++D+G Y Sbjct: 22007 GDNIKVE-IPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPL 22065 Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTF 221 ARN G + T+++H P TGP + VTF Sbjct: 22066 TARNIVG-EVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTF 22105 Score = 43.2 bits (97), Expect = 0.044 Identities = 48/183 (26%), Positives = 73/183 (39%), Gaps = 29/183 (15%) Query: 425 PEPIIAWYFEGEALIQNHRRNVTND-GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483 P P W L + T+ TL +++ +++D+G YT + G Sbjct: 29312 PTPTAVWSKPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSG--------- 29362 Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITH-NVTDTSVTLSWSQNNKIGSSSILGYQVEV 542 + +I F V PGPP PIT +VT S TL W G + I Y VE Sbjct: 29363 -----SKSITF--TVKVLDTPGPPG-PITFKDVTRGSATLMWDAPLLDGGARIHHYVVE- 29413 Query: 543 FSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602 RE + R W VI+ + + + V L G+ Y F V N +G+ P + Sbjct: 29414 -KREA--------SRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMP 29464 Query: 603 DSV 605 + + Sbjct: 29465 EPI 29467 Score = 42.7 bits (96), Expect = 0.059 Identities = 51/178 (28%), Positives = 67/178 (37%), Gaps = 8/178 (4%) Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGL 66 S EAP I E+ TV + A R G P P WYK GV + SD P + Sbjct: 2074 SMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNV 2133 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV- 125 L D+ +A N G S L A F E + + + DT+ Sbjct: 2134 CEL-VIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMA 2192 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDS-RMHLVDGGN-LVIQDARQTDAGRYQCI 181 EC P V W K+G + +GD RMH + L I +DA Y C+ Sbjct: 2193 TFEC--ETSEPFVKVKWYKDGME-VHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCV 2247 Score = 42.7 bits (96), Expect = 0.059 Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 2/98 (2%) Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEY 270 +V + G S G P P++ W R G + K ++ L +DN D G+Y Sbjct: 24961 IVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKY 25020 Query: 271 SCEAENSVGAVSASGYLTVYDPPS--INLSPNSVNVES 306 + ENS G+ SA + V D P NL+ V +S Sbjct: 25021 ILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDS 25058 Score = 42.7 bits (96), Expect = 0.059 Identities = 36/114 (31%), Positives = 46/114 (40%), Gaps = 15/114 (13%) Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE---VFSRETLSGNNT 553 A D + PG P P + T TSV+L+WS G S + GY +E V E N T Sbjct: 30953 AMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTT 31012 Query: 554 PRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607 P R Y + L G Y F V N+ G P+ V +V V Sbjct: 31013 PTKIR------------EYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKV 31054 Score = 42.3 bits (95), Expect = 0.078 Identities = 32/111 (28%), Positives = 53/111 (47%), Gaps = 7/111 (6%) Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556 A D PGPPT + T S+TL W + G + I+GY VE+ R ++ + +P Sbjct: 19417 AKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEM--RPKIA-DASP-- 19471 Query: 557 SRGW--VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605 GW A ++ + + V SL Y F V +N G+ P+ + +++ Sbjct: 19472 DEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAI 19522 Score = 42.3 bits (95), Expect = 0.078 Identities = 34/107 (31%), Positives = 48/107 (44%), Gaps = 12/107 (11%) Query: 506 PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIA- 564 PP +P VT SVTL W + G S I GY VE +E G W+ + Sbjct: 23368 PPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVE--KKELPEGR--------WMKASF 23417 Query: 565 RRVHQTHYVVKSLIPGITYMFIVRTENSHGL-SGPSPVSDSVTVGDD 610 + TH+ V L+ Y F V N+ G+ S PS + ++T D+ Sbjct: 23418 TNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDE 23464 Score = 42.3 bits (95), Expect = 0.078 Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 6/123 (4%) Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSN-SRVAQTLDDV-PDGPPINIEMFILNTTTVH 749 + T L + +YE + + GKPS S+ +D + P G P N + T+V Sbjct: 30918 YRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVS 30977 Query: 750 LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQ 809 L WS PE + +TGY + + +D NTT + +T+L G Y + Sbjct: 30978 LAWSVPEDE-GGSKVTGYLIEMQKVD---QHEWTKCNTTPTKIREYTLTHLPQGAEYRFR 31033 Query: 810 IAA 812 + A Sbjct: 31034 VLA 31036 Score = 41.9 bits (94), Expect = 0.10 Identities = 30/107 (28%), Positives = 46/107 (42%), Gaps = 11/107 (10%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 PG P P V+ +T+ W+ G SI GY +E ++S WV + Sbjct: 19323 PGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLE----------KKEKHSTRWVPV 19372 Query: 564 AR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 + + + V++L+P Y F V+ EN G+ PS S V D Sbjct: 19373 NKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKD 19419 Score = 41.5 bits (93), Expect = 0.14 Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 2/69 (2%) Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQ 179 +G++V LEC G P P V W + + D ++ G L+I++A D+GR+ Sbjct: 956 EGESVTLEC-HISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFT 1014 Query: 180 CIARNAAGT 188 C A N AGT Sbjct: 1015 CSAVNEAGT 1023 Score = 41.5 bits (93), Expect = 0.14 Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 4/86 (4%) Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL---RLDNVILADE 267 + + G++V V G P+P V W++ G P +K+ +L L +V D Sbjct: 20232 LTVKAGTNVCLDATVFGKPMPTVSWKKD-GTLLKPAEGIKMAMQRNLCTLELFSVNRKDS 20290 Query: 268 GEYSCEAENSVGAVSASGYLTVYDPP 293 G+Y+ AENS G+ SA+ L V D P Sbjct: 20291 GDYTITAENSSGSKSATIKLKVLDKP 20316 Score = 41.5 bits (93), Expect = 0.14 Identities = 37/132 (28%), Positives = 65/132 (49%), Gaps = 15/132 (11%) Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPESK-----QSAQ-GDTVVLECLPPRGSPEPN 139 +A N G + R L V V+ ++ ++P K S Q G+ + +E +P G P PN Sbjct: 25213 KAYNEKGKSDPR--VLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIE-IPVIGRPRPN 25269 Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIARNAAGTRESAIATL 196 + W K+G+ L +R+++ + L I++ + D G+Y A N+AGT ++ + Sbjct: 25270 ISWVKDGEPL--KQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVI 25327 Query: 197 KIHIKPYLITGP 208 + KP GP Sbjct: 25328 VLE-KPGPPVGP 25338 Score = 41.5 bits (93), Expect = 0.14 Identities = 33/108 (30%), Positives = 46/108 (42%), Gaps = 12/108 (11%) Query: 506 PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV-VIA 564 PP P +VT ++TL W+ + G S I+GY +E R+ GN WV Sbjct: 28784 PPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIE--KRQ---GNER------WVRCNF 28832 Query: 565 RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSN 612 V + Y V L PG Y F + N+ G P S + + D N Sbjct: 28833 TDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDEN 28880 Score = 41.1 bits (92), Expect = 0.18 Identities = 30/102 (29%), Positives = 42/102 (41%), Gaps = 8/102 (7%) Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352 P I L P V V G ARF C TG P+P + W + G + R +DG Sbjct: 1841 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQ-------LIRKSKRFRVRYDG 1893 Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394 + L I D D+ + +A N G + KL + +D Sbjct: 1894 IHYLDIVDCKSYDT-GEVKVTAENPEGVIEHKVKLEIQQRED 1934 Score = 41.1 bits (92), Expect = 0.18 Identities = 45/186 (24%), Positives = 71/186 (38%), Gaps = 29/186 (15%) Query: 425 PEPIIAWYFEGEALIQNHR---RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481 P P W F + L R + ++ LV+ ++SD G YT +R Sbjct: 14349 PRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENR--------V 14400 Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541 + I+ N V + P P + ++T SV L+W + G S + GY VE Sbjct: 14401 KTISGEIDVN--------VIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVE 14452 Query: 542 VFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPV 601 RE + + W + V + V L+ G Y+F V N G P+ V Sbjct: 14453 --KREV--------SRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYV 14502 Query: 602 SDSVTV 607 + V + Sbjct: 14503 DEPVNM 14508 Score = 41.1 bits (92), Expect = 0.18 Identities = 31/99 (31%), Positives = 45/99 (45%), Gaps = 4/99 (4%) Query: 214 QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGEYSC 272 + G S+ + G P P+V W + G + V SL LDNV D G+Y+ Sbjct: 23882 RAGGSLRLFVPIKGRPTPEVKWGK-VDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTL 23940 Query: 273 EAENSVGAVSASGYLTVYDPPS--INLSPNSVNVESGNV 309 ENS G SA + V D PS +NL + +S ++ Sbjct: 23941 TLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSI 23979 Score = 40.7 bits (91), Expect = 0.24 Identities = 55/220 (25%), Positives = 72/220 (32%), Gaps = 35/220 (15%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL---DDGSLR 258 P I + G T V G P P + W + G P K + DD SL Sbjct: 3503 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFN-GVLLTPSADYKFVFDGDDHSLI 3561 Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYD-------------------------PP 293 + L DEGEY+C A N G S YL + PP Sbjct: 3562 ILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPP 3621 Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353 + G A F T G P PT+ W E + + Y +G Sbjct: 3622 HFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQL-----CTSVYYTIIHNPNGS 3676 Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393 +ND + DS +C A N G S +L V +D Sbjct: 3677 GTFIVNDPQREDS-GLYICKAENMLGESTCAAELLVLLED 3715 Score = 40.7 bits (91), Expect = 0.24 Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 2/84 (2%) Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL-DNVILADEGE 269 V + G+S+ V G P P + W + G + + SL + D V D G+ Sbjct: 30383 VTIRAGASLRLMVSVSGRPPPVITWSKQ-GIDLASRAIIDTTESYSLLIVDKVNRYDAGK 30441 Query: 270 YSCEAENSVGAVSASGYLTVYDPP 293 Y+ EAEN G SA+ + VYD P Sbjct: 30442 YTIEAENQSGKKSATVLVKVYDTP 30465 Score = 40.3 bits (90), Expect = 0.31 Identities = 25/96 (26%), Positives = 41/96 (42%), Gaps = 2/96 (2%) Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS--LRLDNVILAD 266 E +V + G++V F + G P+P W D+ S L + N + D Sbjct: 18445 EGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRD 18504 Query: 267 EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302 GEY N+ G+ + + +LTV D P P ++ Sbjct: 18505 TGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINI 18540 Score = 40.3 bits (90), Expect = 0.31 Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 1/56 (1%) Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGT 188 G P P WKK ++ +H D + L+I+D + D+G Y A N++GT Sbjct: 19851 GKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGT 19906 Score = 40.3 bits (90), Expect = 0.31 Identities = 33/106 (31%), Positives = 47/106 (44%), Gaps = 10/106 (9%) Query: 506 PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565 PP +P N+T SV+L WS+ + G + I GY VE RE G N Sbjct: 26614 PPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVE--RRELPDGRWLKCN-------YT 26664 Query: 566 RVHQTHYVVKSLIPGITYMFIVRTEN-SHGLSGPSPVSDSVTVGDD 610 + +T++ V L Y F V N + +S PS + + V DD Sbjct: 26665 NIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDD 26710 Score = 40.3 bits (90), Expect = 0.31 Identities = 50/190 (26%), Positives = 75/190 (39%), Gaps = 17/190 (8%) Query: 217 SSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---RVKVLDDG--SLRLDNVILADEGEYS 271 S+ T C+V G P P V W R G + G R++ G L + +V D Y Sbjct: 31870 SNATLVCKVTGHPKPIVKWYRQ-GKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQ 31928 Query: 272 CEAENSVGAVSASGYLTVYDPPSINL-----SPNSVNVESGNVARFTCTATGRPEPTMFW 326 A N G+VS + L V P I+L +V+ G V +G+P+P + W Sbjct: 31929 VRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITW 31988 Query: 327 SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386 +G I G Y +++ N ++ D+ +VC A N G + Sbjct: 31989 Q-KGQDLIDNNG----HYQVIVTRSFTSLVFPNGVERKDAGFYVVC-AKNRFGIDQKTVE 32042 Query: 387 LTVTSDDDRP 396 L V D P Sbjct: 32043 LDVADVPDPP 32052 Score = 39.9 bits (89), Expect = 0.41 Identities = 39/141 (27%), Positives = 69/141 (48%), Gaps = 18/141 (12%) Query: 87 ATNSYGTARSRNATLHVAVLREEFRLEPE-----SKQSAQ-GDTVVLECLPPRGSPEPNV 140 A N G RS +L V ++ ++ +EP+ S S Q G + +E +P G P+P + Sbjct: 24132 AVNEKG--RSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIE-VPISGRPKPTI 24188 Query: 141 YWKKNGQTLLFDGDSRMHLVDGGNLV---IQDARQTDAGRYQCIARNAAGTRESAIATLK 197 W K+G L +R+++ D +L I++ + D G+Y N G + ++I + Sbjct: 24189 TWTKDG--LPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVT 24246 Query: 198 IHIKPYLITGP---EDVVAQT 215 + KP GP +DV A++ Sbjct: 24247 LD-KPDPPKGPVKFDDVSAES 24266 Score = 39.5 bits (88), Expect = 0.55 Identities = 30/83 (36%), Positives = 37/83 (44%), Gaps = 3/83 (3%) Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLD 260 KP ++ PE V G + F+CRV G P P V W + G R +V DG LD Sbjct: 1840 KPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLN-GQLIRKSKRFRVRYDGIHYLD 1898 Query: 261 NVILA--DEGEYSCEAENSVGAV 281 V D GE AEN G + Sbjct: 1899 IVDCKSYDTGEVKVTAENPEGVI 1921 Score = 39.5 bits (88), Expect = 0.55 Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 4/92 (4%) Query: 729 DVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTT 788 D P GPPIN + T+V KW PP L I Y + P ++ +V +T Sbjct: 15727 DTP-GPPINFVFEDIRKTSVLCKWEPP-LDDGGSEIINYTLEKKDKTKPDSEWIVVTSTL 15784 Query: 789 VHQATSLIMTNLTSGVSYSVQIAAETIIGLGP 820 H S +T L G Y ++ AE G GP Sbjct: 15785 RHCKYS--VTKLIEGKEYLFRVRAENRFGPGP 15814 Score = 39.5 bits (88), Expect = 0.55 Identities = 35/130 (26%), Positives = 58/130 (44%), Gaps = 5/130 (3%) Query: 695 TSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDV-PDGPPINIEMFILNTTTVHLKWS 753 T L + +Y F + +G+P S + +D P GPP E+ + T + W Sbjct: 21461 TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWK 21520 Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAE 813 P + ITGY+ V + + + + AI T V + T L G +Y +++AE Sbjct: 21521 RP-VDDGGSEITGYH--VERREKKSLRWVRAIKTPVSDLRCKV-TGLQEGSTYEFRVSAE 21576 Query: 814 TIIGLGPFSQ 823 G+GP S+ Sbjct: 21577 NRAGIGPPSE 21586 Score = 39.5 bits (88), Expect = 0.55 Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 4/99 (4%) Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGE 269 VV + +++ + G P P+V W + A G +++V + L +DNV D G Sbjct: 26044 VVLRASATLRLFVTIKGRPEPEVKWEK-AEGILTDRAQIEVTSSFTMLVIDNVTRFDSGR 26102 Query: 270 YSCEAENSVGAVSASGYLTVYDPPS--INLSPNSVNVES 306 Y+ EN+ G+ +A + V D PS +NL+ V +S Sbjct: 26103 YNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDS 26141 Score = 39.5 bits (88), Expect = 0.55 Identities = 35/131 (26%), Positives = 57/131 (43%), Gaps = 5/131 (3%) Query: 690 SGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVP-DGPPINIEMFILNTTTV 748 S F+ T L + +Y F + + G S V + + GPP +++F ++ + Sbjct: 30816 STFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGM 30875 Query: 749 HLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSV 808 L W PPE +TGY +V +V A++ V +N T T LT G+ Y Sbjct: 30876 TLTWYPPE-DDGGSQVTGY--IVERKEVRADR-WVRVNKVPVTMTRYRSTGLTEGLEYEH 30931 Query: 809 QIAAETIIGLG 819 ++ A G G Sbjct: 30932 RVTAINARGSG 30942 Score = 39.1 bits (87), Expect = 0.72 Identities = 53/234 (22%), Positives = 86/234 (36%), Gaps = 39/234 (16%) Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW-----SVEGN------------RTI 334 PP++ +V V G C +G P PT+ W +E + R + Sbjct: 942 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 1001 Query: 335 IFPGMSRD--KYHATAVFDGVTV-----LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387 I + D ++ +AV + TV L + +++ + T V FV + Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRD 1061 Query: 388 TVTSDD----------DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437 V +D + P P Q L VF C P+P + W G Sbjct: 1062 VVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVP 1121 Query: 438 LIQNHRRNV-----TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486 L +R V T + LV+ D+G YT V ++HG+ S +LL ++ Sbjct: 1122 LTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEA 1175 Score = 39.1 bits (87), Expect = 0.72 Identities = 41/198 (20%), Positives = 81/198 (40%), Gaps = 12/198 (6%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-THRSILPAGGLFFLR 70 P + +P+ Q A + + G P P W+ G +V+D TH+ ++ G L Sbjct: 1457 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1516 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR---LEPESKQSAQGDTVVL 127 SD+G + A N G + S + L V + + + +E + + + + Sbjct: 1517 IVPA-TPSDSGEWTVVAQNRAGRS-SISVILTVEAVEHQVKPMFVEKLKNVNIKEGSQLE 1574 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG----GNLVIQDARQTDAGRYQCIAR 183 + G+P P++ W KN ++ ++ ++G L I D+ Y A Sbjct: 1575 MKVRATGNPNPDIVWLKNSDIIVPHKYPKIR-IEGTKGEAALKIDSTVSQDSAWYTATAI 1633 Query: 184 NAAGTRESAIATLKIHIK 201 N AG R++ + + ++ Sbjct: 1634 NKAG-RDTTRCKVNVEVE 1650 Score = 39.1 bits (87), Expect = 0.72 Identities = 32/112 (28%), Positives = 55/112 (49%), Gaps = 11/112 (9%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAG--GSPSPAIRW-YKGGVLVVSDTHRSILPAGGL 66 + P+ ++ + + R PA CR G P+ + W + G L ++ R I G Sbjct: 1701 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFG-- 1758 Query: 67 FFLRATHGRVHS-DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK 117 + +G +S D+G+ C ATN YGT + +ATL ++++E L ES+ Sbjct: 1759 -YCSLDYGVAYSRDSGIITCRATNKYGTDHT-SATL---IVKDEKSLVEESQ 1805 Score = 39.1 bits (87), Expect = 0.72 Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 5/84 (5%) Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL---VDGGNLVIQDARQTDAGRY 178 GDT+ LE RG P P V W K+ R+ + D + A+++D G+Y Sbjct: 19143 GDTIRLEA-GVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKY 19201 Query: 179 QCIARNAAGTRESAIATLKIHIKP 202 A N AG+ A AT+ + KP Sbjct: 19202 VVTATNTAGS-FVAYATVNVLDKP 19224 Score = 39.1 bits (87), Expect = 0.72 Identities = 37/132 (28%), Positives = 59/132 (44%), Gaps = 11/132 (8%) Query: 692 FEITSLRKYTKYEFFLIPF--YKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVH 749 F +T L + +Y F + Y EG S VA+ DVPD PP + + +V Sbjct: 21062 FRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPP-NIVDVRHDSVS 21120 Query: 750 LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMV--AINTTVHQATSLIMTNLTSGVSYS 807 L W+ P+ + ITGY+ L+ S++ N T + +T LT G+ Y Sbjct: 21121 LTWTDPK-KTGGSPITGYH-----LEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYE 21174 Query: 808 VQIAAETIIGLG 819 ++ A + G+G Sbjct: 21175 FRVMAINLAGVG 21186 Score = 39.1 bits (87), Expect = 0.72 Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 8/105 (7%) Query: 499 DVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558 D + PGPP+ P + T S +L+W + + G I GY VE + + +++ Sbjct: 21595 DAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVE---HQKVGDEAWIKDTT 21651 Query: 559 GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603 G A R+ T +VV L Y F + N G+ P+ + D Sbjct: 21652 G---TALRI--TQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPD 21691 Score = 38.7 bits (86), Expect = 0.96 Identities = 69/306 (22%), Positives = 114/306 (37%), Gaps = 19/306 (6%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 EA I + ++TV Q A ++W K GV++ S+ +I G ++ L Sbjct: 2705 EAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSL 2764 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 R + + D VY +AR LHV ++ +P+ + + TV E Sbjct: 2765 RIKNCAI-VDESVYGFRLGRLGASAR-----LHVETVK--IIKKPKDVTALENATVAFE- 2815 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189 + P ++ KN + D + L++Q+ +DAG Y + Sbjct: 2816 VSVSHDTVPVKWFHKNVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAVVGQLECKA 2875 Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249 + + TL I I PE A +F+C V +P +W ++ M + Sbjct: 2876 KLFVETLHITKTMKNIEVPETKTA------SFECEVSHFNVPS-MWLKNGVEIEMS-EKF 2927 Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309 K++ G L +I+ E S E G S LTV P I +N E + Sbjct: 2928 KIVVQGKLH-QLIIMNTSTEDSAEYTFVCGNDQVSATLTV-TPIMITSMLKDINAEEKDT 2985 Query: 310 ARFTCT 315 F T Sbjct: 2986 ITFEVT 2991 Score = 38.7 bits (86), Expect = 0.96 Identities = 25/89 (28%), Positives = 43/89 (48%), Gaps = 6/89 (6%) Query: 731 PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH 790 P GPP ++ ++ T V L W+ P+ ITGY +V + + + + T + Sbjct: 18336 PPGPPKDLHHVDVDKTEVSLVWNKPDRD-GGSPITGY--LVEYQE-EGTQDWIKFKTVTN 18391 Query: 791 QATSLIMTNLTSGVSYSVQIAAETIIGLG 819 ++T L G +Y ++ AE I+GLG Sbjct: 18392 --LECVVTGLQQGKTYRFRVKAENIVGLG 18418 Score = 38.7 bits (86), Expect = 0.96 Identities = 29/112 (25%), Positives = 49/112 (43%), Gaps = 9/112 (8%) Query: 87 ATNSYGTARSRNATLHVAVLREEFR-----LEPESKQSAQ---GDTVVLECLPPRGSPEP 138 A N+ G + + + + ++E+ L+P K GDT+VL + G P P Sbjct: 21277 AKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLP 21336 Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTR 189 W K G+ + +++ + L I+ A + DAG Y A N GT+ Sbjct: 21337 KSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTK 21388 Score = 38.7 bits (86), Expect = 0.96 Identities = 48/186 (25%), Positives = 75/186 (40%), Gaps = 17/186 (9%) Query: 41 PAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV--HSDAGVYWCEATNSYGTARSRN 98 P RW K + DTH + GL RV + AGV+ E + S G +R+ Sbjct: 23408 PEGRWMKASFTNIIDTHFEVT---GLVEDHRYEFRVIARNAAGVF-SEPSESTGAITARD 23463 Query: 99 ATLHVAVLREEFRLEPESKQSA---QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155 V ++P+ K + G++ ++ G P P + W K Q L Sbjct: 23464 E-----VDPPRISMDPKYKDTIVVHAGESFKVDA-DIYGKPIPTIQWIKGDQELSNTARL 23517 Query: 156 RMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQ 214 + D +L ++DA + D+G Y A+N AG R S +K+ +P GP + Sbjct: 23518 EIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGER-SVTVNVKVLDRPGPPEGPVVISGV 23576 Query: 215 TGSSVT 220 T T Sbjct: 23577 TAEKCT 23582 Score = 38.7 bits (86), Expect = 0.96 Identities = 32/107 (29%), Positives = 47/107 (43%), Gaps = 12/107 (11%) Query: 506 PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIA- 564 PP +P +T +VTL W + G S I GY VE ++ G W+ + Sbjct: 25532 PPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVE--KKDLPDGR--------WMKASF 25581 Query: 565 RRVHQTHYVVKSLIPGITYMFIVRTENSHG-LSGPSPVSDSVTVGDD 610 V +T + V L+ Y F V N+ G S PS S ++T D+ Sbjct: 25582 TNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDE 25628 Score = 38.7 bits (86), Expect = 0.96 Identities = 29/98 (29%), Positives = 48/98 (48%), Gaps = 6/98 (6%) Query: 134 GSPEPNVYWKKNGQTLLFDGDSRM-HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192 G P P + W K+ + L + + + D +++I+DA + ++G Y+ RNA G SA Sbjct: 27825 GKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMG---SA 27881 Query: 193 IATLKIHI--KPYLITGPEDVVAQTGSSVTFQCRVGGD 228 AT+++ I KP GP + T +T R D Sbjct: 27882 SATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPAD 27919 Score = 38.3 bits (85), Expect = 1.3 Identities = 31/117 (26%), Positives = 47/117 (40%), Gaps = 11/117 (9%) Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556 A D + PGPP +VT V L W G I Y +E +E L Sbjct: 15104 AKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIE--KKERLGTR----- 15156 Query: 557 SRGWVVIARRV-HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSN 612 WV + ++ V +I G F VR EN G+ PS ++ +++ D ++ Sbjct: 15157 ---WVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTS 15210 Score = 38.3 bits (85), Expect = 1.3 Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 11/113 (9%) Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556 A D S PGPP +T + + T++ L W G I+GY V+ ++ + N R Sbjct: 15923 AHDPISPPGPPIPRVT-DTSSTTIELEWEPPAFNGGGEIVGYFVD---KQLVGTNEWSRC 15978 Query: 557 SRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 + + +V Q Y VK + G Y V N+ G GP + VTV + Sbjct: 15979 TEKMI----KVRQ--YTVKEIREGADYKLRVSAVNAAG-EGPPGETQPVTVAE 16024 Score = 38.3 bits (85), Expect = 1.3 Identities = 27/92 (29%), Positives = 45/92 (48%), Gaps = 5/92 (5%) Query: 729 DVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTT 788 D+P P I+ +++ V W PPE +G + N VV + + V + TT Sbjct: 22084 DIPGPPTGPIKFDEVSSDFVTFSWDPPE---NDGGVPISNYVVEMRQTDST-TWVELATT 22139 Query: 789 VHQATSLIMTNLTSGVSYSVQIAAETIIGLGP 820 V + T+ T LT+G+ Y ++ A+ G+GP Sbjct: 22140 VIR-TTYKATRLTTGLEYQFRVKAQNRYGVGP 22170 Score = 38.3 bits (85), Expect = 1.3 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 6/91 (6%) Query: 729 DVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTT 788 D P PP+N+++ + +V + W PP L +G N +V + KS A+ T Sbjct: 23959 DTPS-PPVNLKVTEITKDSVSITWEPP---LLDGGSKIKNYIVEKREA-TRKSYAAVVTN 24013 Query: 789 VHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819 H+ S + L G SY ++ AE G+G Sbjct: 24014 CHK-NSWKIDQLQEGCSYYFRVTAENEYGIG 24043 Score = 38.3 bits (85), Expect = 1.3 Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 6/81 (7%) Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIARNAAGTRE 190 G P P + W K+G + + +R ++ N L ++D + D G+Y +N AGTR Sbjct: 26742 GRPLPVISWAKDG--IEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRS 26799 Query: 191 SAIATLKIHIKPYLITGPEDV 211 A+ K+ KP GP ++ Sbjct: 26800 VAV-NCKVLDKPGPPAGPLEI 26819 Score = 38.3 bits (85), Expect = 1.3 Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 1/70 (1%) Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGT 188 +P +G P P V W+K+ + L D + D +L+ I + D G+Y N G Sbjct: 28220 IPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGE 28279 Query: 189 RESAIATLKI 198 +S+ ++K+ Sbjct: 28280 PKSSTVSVKV 28289 Score = 38.3 bits (85), Expect = 1.3 Identities = 28/102 (27%), Positives = 51/102 (50%), Gaps = 7/102 (6%) Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD---GGNLVIQDARQTDAGRY 178 G+++ ++ L +G P P V W K+G + + M + D +L ++DA + G Y Sbjct: 28900 GESLRIKALV-QGRPVPRVTWFKDGVEI--EKRMNMEITDVLGSTSLFVRDATRDHRGVY 28956 Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVT 220 A+NA+G+ ++ I +K+ P + GP TG +T Sbjct: 28957 TVEAKNASGSAKAEI-KVKVQDTPGKVVGPIRFTNITGEKMT 28997 Score = 37.9 bits (84), Expect = 1.7 Identities = 77/332 (23%), Positives = 130/332 (39%), Gaps = 52/332 (15%) Query: 291 DPPSINLSPN---SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347 +PP++ L + + + +G R TGRP PT W+ E + +D+ Sbjct: 16027 EPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGE------LDKDR---- 16076 Query: 348 AVFDGV---TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404 V D V + L I D + D V +A N GS F ++ V D P P++ P Sbjct: 16077 VVIDNVGTKSELIIKDALRKD-HGRYVITATNSCGSKFAAARVEVF---DVPGPVLDLKP 16132 Query: 405 --SNQTLPIKSMAVFPCTAICTPEPIIAWYFE-GEALIQNHRRNV-TNDGTLVLKDLDKS 460 +N+ + + + + I + E +A + R+ + T + L + Sbjct: 16133 VVTNRKMCLLNWSDPEDDG---GSEITGFIIERKDAKMHTWRQPIETERSKCDITGLLEG 16189 Query: 461 DSGTYTCVASSRH--GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDT 518 + +A ++ G V G +L P+ P P P + T + Sbjct: 16190 QEYKFRVIAKNKFGCGPPVEIGPILAVDPLGP-------------PTSPERLTYTERTKS 16236 Query: 519 SVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLI 578 ++TL W + G S I GY +E R ++ P R V R T ++V++L Sbjct: 16237 TITLDWKEPRSNGGSPIQGYIIE--KRR----HDKPDFER---VNKRLCPTTSFLVENLD 16287 Query: 579 PGITYMFIVRTENSHGLSGPSPVSDSVTVGDD 610 Y F V+ N G S PS + +V + DD Sbjct: 16288 EHQMYEFRVKAVNEIGESEPS-LPLNVVIQDD 16318 Score = 37.9 bits (84), Expect = 1.7 Identities = 25/100 (25%), Positives = 42/100 (42%), Gaps = 4/100 (4%) Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKV---LDDGSLRLDNVILAD 266 + + G ++ + V G P P+V W + ++ RVK+ D L +D Sbjct: 19138 LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSD 19197 Query: 267 EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306 G+Y A N+ G+ A + V D P + V+V S Sbjct: 19198 GGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSS 19237 Score = 37.9 bits (84), Expect = 1.7 Identities = 40/185 (21%), Positives = 70/185 (37%), Gaps = 22/185 (11%) Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 P P + W + +N+ +D +++ D S T V + GKY+ + V Sbjct: 28226 PPPTVTW--------RKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGV 28277 Query: 485 DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFS 544 P + + + V P K +V+ +VTL W G S I+ Y +E Sbjct: 28278 GEPKSSTV----SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIE--K 28331 Query: 545 RETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDS 604 R+ R W V++ + T + + L + F V EN G+ P ++ Sbjct: 28332 RDA--------TKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEP 28383 Query: 605 VTVGD 609 V + Sbjct: 28384 VKAAE 28388 Score = 37.9 bits (84), Expect = 1.7 Identities = 31/120 (25%), Positives = 51/120 (42%), Gaps = 12/120 (10%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 P PP + + + +S L+W + + G S I GY +E+ + S WV Sbjct: 29473 PAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEM----------RQKGSDFWVE- 29521 Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDS-NSLWEGTGVSN 622 A Q + V+ L+ Y F V+ +N G S P SV + + + TG++N Sbjct: 29522 AGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITN 29581 Score = 37.9 bits (84), Expect = 1.7 Identities = 38/153 (24%), Positives = 64/153 (41%), Gaps = 9/153 (5%) Query: 44 RWYKGGVLVVSDTHRSI--LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATL 101 RW K +VSD ++ L G + R + AGV + + S G R+ Sbjct: 29914 RWLKCNYTIVSDNFFTVTALSEGDTYEFRVL---AKNAAGVI-SKGSESTGPVTCRDEYA 29969 Query: 102 HVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLV 160 + RL + G +VL+ G PEP + W K + L L + S + Sbjct: 29970 PPKA-ELDARLHGDLVTIRAGSDLVLDAAVG-GKPEPKIIWTKGDKELDLCEKVSLQYTG 30027 Query: 161 DGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193 VI+ ++D+G+Y +NA+GT+ ++ Sbjct: 30028 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSV 30060 Score = 37.5 bits (83), Expect = 2.2 Identities = 28/117 (23%), Positives = 50/117 (42%), Gaps = 10/117 (8%) Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---- 255 IK L + + + G V V G P+P + W ++ P +++ + Sbjct: 16324 IKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRS 16383 Query: 256 ----SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS--INLSPNSVNVES 306 L + + D+G Y+ A N +G+V + ++ VYD PS NL+ + ES Sbjct: 16384 EAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAES 16440 Score = 37.5 bits (83), Expect = 2.2 Identities = 35/127 (27%), Positives = 51/127 (40%), Gaps = 5/127 (3%) Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751 F+ T L + +YEF + GKPS D P PP E I+ +V L+ Sbjct: 23327 FKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARD-PCDPPGRPEAIIVTRNSVTLQ 23385 Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811 W P ITGY +V ++P + M A T + T +T L Y ++ Sbjct: 23386 WKKPTYD-GGSKITGY--IVEKKELPEGRWMKASFTNIID-THFEVTGLVEDHRYEFRVI 23441 Query: 812 AETIIGL 818 A G+ Sbjct: 23442 ARNAAGV 23448 Score = 37.5 bits (83), Expect = 2.2 Identities = 32/105 (30%), Positives = 45/105 (42%), Gaps = 10/105 (9%) Query: 506 PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565 PP +++ SV+LSW Q G S I GY VE R+ G T + Sbjct: 27697 PPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVE--RRDLPDGRWTKAS-------FT 27747 Query: 566 RVHQTHYVVKSLIPGITYMFIVRTENSHG-LSGPSPVSDSVTVGD 609 V +T +++ L Y F V N+ G +S PS V +T D Sbjct: 27748 NVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCID 27792 Score = 37.5 bits (83), Expect = 2.2 Identities = 30/106 (28%), Positives = 45/106 (42%), Gaps = 9/106 (8%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 PGPPT + + T+V+L WS+ G I+GY +E+ + G+ N+ V Sbjct: 29181 PGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADL--GDWHKVNAEACV-- 29236 Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 +T Y V L G Y F V N G V+ ++ D Sbjct: 29237 -----KTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVD 29277 Score = 37.5 bits (83), Expect = 2.2 Identities = 22/79 (27%), Positives = 32/79 (40%), Gaps = 3/79 (3%) Query: 400 ITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN---DGTLVLKD 456 I P + T+ A F C P P + W +G+ L + R VT T + Sbjct: 33490 ILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISS 33549 Query: 457 LDKSDSGTYTCVASSRHGK 475 + SD G Y+ V + GK Sbjct: 33550 VQASDEGNYSVVVENSEGK 33568 Score = 37.1 bits (82), Expect = 2.9 Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 2/89 (2%) Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRES 191 RG P P W +G + D + + + L I++ + D G YQ NAAG++ Sbjct: 18462 RGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTV 18521 Query: 192 AIATLKIHIKPYLITGPEDVVAQTGSSVT 220 A+ + + P TGP +++ T +T Sbjct: 18522 AVHLTVLDV-PGPPTGPINILDVTPEHMT 18549 Score = 37.1 bits (82), Expect = 2.9 Identities = 30/110 (27%), Positives = 41/110 (37%), Gaps = 11/110 (10%) Query: 500 VSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRG 559 VS P PP + +VT + T+ W + G S I GY VE+ + S Sbjct: 26219 VSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEM----------QTKGSEK 26268 Query: 560 WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 W +V + L G Y+F V N G S P + V D Sbjct: 26269 WST-CTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARD 26317 Score = 36.7 bits (81), Expect = 3.9 Identities = 16/52 (30%), Positives = 26/52 (50%), Gaps = 2/52 (3%) Query: 1 MSDDYVTSGE--APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV 50 ++++ GE APY I +P+ + C+ GG+P P + W K GV Sbjct: 1069 LTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1120 Score = 36.7 bits (81), Expect = 3.9 Identities = 37/124 (29%), Positives = 53/124 (42%), Gaps = 10/124 (8%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVI 167 F E + + GD L + G P+P + W NG L D + + DG + L+I Sbjct: 3505 FIKEVSNADISMGDVATLS-VTVIGIPKPKIQWFFNGVLLTPSADYKF-VFDGDDHSLII 3562 Query: 168 QDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGG 227 + D G Y C+A N G + A LKI+ K G +D +T S+V G Sbjct: 3563 LFTKLEDEGEYTCMASNDYG-KTICSAYLKINSKG---EGHKD--TETESAVAKSLEKLG 3616 Query: 228 DPLP 231 P P Sbjct: 3617 GPCP 3620 Score = 36.7 bits (81), Expect = 3.9 Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 2/83 (2%) Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGTRESA 192 G P P + W K+G+ L + + D NLV +D+ + D+G Y A N G + Sbjct: 22414 GRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKH- 22472 Query: 193 IATLKIHIKPYLITGPEDVVAQT 215 I +K+ +P GP V T Sbjct: 22473 IFNVKVLDRPGPPEGPLAVTEVT 22495 Score = 36.7 bits (81), Expect = 3.9 Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 9/103 (8%) Query: 719 SNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPA 778 S VAQ VP GPP + + + ++ ++W+ P + +G G V+ L+ Sbjct: 23256 SEPTVAQYPFKVP-GPPGTPVVTLSSRDSMEVQWNEP---ISDG---GSRVIGYHLERKE 23308 Query: 779 NKSM--VAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819 S+ V +N T T T L GV Y +++AE I+G+G Sbjct: 23309 RNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIG 23351 Score = 36.7 bits (81), Expect = 3.9 Identities = 20/62 (32%), Positives = 36/62 (58%), Gaps = 5/62 (8%) Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCIARNAA 186 +P +G P+ V W+K+GQTL +R+++ +L I++A + D G Y+ N+A Sbjct: 26343 VPFKGRPQATVNWRKDGQTL--KETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSA 26400 Query: 187 GT 188 G+ Sbjct: 26401 GS 26402 Score = 36.7 bits (81), Expect = 3.9 Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 6/123 (4%) Query: 702 KYEFFLIPFYKKFEGKPSNSR--VAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQL 759 +Y+F + K G+P +S VAQ VPD P I E + ++ L W+ PE Sbjct: 29048 EYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIP-EPSNITGNSITLTWARPE--- 29103 Query: 760 QNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819 +G ++ + + + + I+ T +T LT G Y + AE G+G Sbjct: 29104 SDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVG 29163 Query: 820 PFS 822 P S Sbjct: 29164 PAS 29166 Score = 36.3 bits (80), Expect = 5.1 Identities = 34/126 (26%), Positives = 51/126 (40%), Gaps = 10/126 (7%) Query: 177 RYQCIARNAAGTRESAIATLKIHIK-----PYLITGPEDVVAQ---TGSSVTFQCRVGGD 228 +++ +A NAAG + A + +K P LI Q G ++ + G Sbjct: 18113 KFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGV 18172 Query: 229 PLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYL 287 P P V W++ R+ V GS L + N D G YS EN G+ + S + Sbjct: 18173 PFPKVTWKKEDRDAPTK-ARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKV 18231 Query: 288 TVYDPP 293 V D P Sbjct: 18232 LVLDKP 18237 Score = 36.3 bits (80), Expect = 5.1 Identities = 28/89 (31%), Positives = 42/89 (47%), Gaps = 5/89 (5%) Query: 733 GPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQA 792 GPP ++E+ + + +L W P L +IT Y VV DV A+ ++ T + Sbjct: 18238 GPPRDLEVSEIRKDSCYLTWKEP-LDDGGSVITNY--VVERRDV-ASAQWSPLSAT-SKK 18292 Query: 793 TSLIMTNLTSGVSYSVQIAAETIIGLGPF 821 S +L G Y ++AAE G GPF Sbjct: 18293 KSHFAKHLNEGNQYLFRVAAENQYGRGPF 18321 Score = 36.3 bits (80), Expect = 5.1 Identities = 22/68 (32%), Positives = 39/68 (57%), Gaps = 6/68 (8%) Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCIARNAAG-T 188 +G PEP++ W K G+ L+ + R+ L+ L I++A + D G+Y A+N++G Sbjct: 18860 KGRPEPDITWTKEGKVLV--REKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHA 18917 Query: 189 RESAIATL 196 + SAI + Sbjct: 18918 QGSAIVNV 18925 Score = 36.3 bits (80), Expect = 5.1 Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 6/91 (6%) Query: 729 DVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTT 788 D P GPP ++++ + T+V L W PP L +G N +V + K+ + T Sbjct: 22877 DTP-GPPQDLKVKEVTKTSVTLTWDPP---LLDGGSKIKNYIVEKRE-STRKAYSTVATN 22931 Query: 789 VHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819 H+ TS + L G SY ++ AE G+G Sbjct: 22932 CHK-TSWKVDQLQEGCSYYFRVLAENEYGIG 22961 Score = 36.3 bits (80), Expect = 5.1 Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 4/99 (4%) Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGE 269 ++ + G+S T G P+P+VLW + V D SL ++N D G+ Sbjct: 27123 LIVKAGASFTMTVPFRGRPVPNVLWSK-PDTDLRTRAYVDTTDSRTSLTIENANRNDSGK 27181 Query: 270 YSCEAENSVGAVSASGYLTVYDPPS--INLSPNSVNVES 306 Y+ +N + A S + + V D P N++ V ES Sbjct: 27182 YTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKES 27220 Score = 36.3 bits (80), Expect = 5.1 Identities = 27/98 (27%), Positives = 42/98 (42%), Gaps = 4/98 (4%) Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86 Q R G P P ++W K G + + I+ G ++ + D G Y Sbjct: 32737 QSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVT 32796 Query: 87 ATNSYGTARSRNATLHVAVLR---EEFRLEPESKQSAQ 121 ATN+ G+ S A L V LR +EF+ + E ++ Q Sbjct: 32797 ATNTAGST-SCQAHLQVERLRYKKQEFKSKEEHERHVQ 32833 Score = 35.9 bits (79), Expect = 6.7 Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 4/102 (3%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 + P I+ P V V + A CR G P P + WY G L + + R + G+ +L Sbjct: 1839 QKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQL-IRKSKRFRVRYDGIHYL 1897 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR 111 + + D G A N G + L + RE+FR Sbjct: 1898 DIVDCKSY-DTGEVKVTAENPEGVIEHK-VKLEIQ-QREDFR 1936 Score = 35.9 bits (79), Expect = 6.7 Identities = 24/82 (29%), Positives = 33/82 (40%), Gaps = 1/82 (1%) Query: 112 LEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR 171 L PE + +G+T C G P+P V W NGQ + R+ L I D + Sbjct: 1845 LYPEPVRVLEGETARFRCRVT-GYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCK 1903 Query: 172 QTDAGRYQCIARNAAGTRESAI 193 D G + A N G E + Sbjct: 1904 SYDTGEVKVTAENPEGVIEHKV 1925 Score = 35.9 bits (79), Expect = 6.7 Identities = 33/132 (25%), Positives = 57/132 (43%), Gaps = 8/132 (6%) Query: 690 SGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDV---PDGPPINIEMFILNTT 746 + F +T+L +Y F + + G P++ D PD PP +E+ + Sbjct: 19682 TSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPD-PPRKLEVTEMTKN 19740 Query: 747 TVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSY 806 + L W PP L+ I GY + PA++ +V + SL++T L G Y Sbjct: 19741 SATLAWLPP-LRDGGAKIDGYITSYREEEQPADRWT---EYSVVKDLSLVVTGLKEGKKY 19796 Query: 807 SVQIAAETIIGL 818 ++AA +G+ Sbjct: 19797 KFRVAARNAVGV 19808 Score = 35.9 bits (79), Expect = 6.7 Identities = 23/82 (28%), Positives = 33/82 (40%), Gaps = 1/82 (1%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I P +T+ + + G P P +W KG VV+ +H ++ A L Sbjct: 19826 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSIL-I 19884 Query: 72 THGRVHSDAGVYWCEATNSYGT 93 D+G Y A NS GT Sbjct: 19885 IKDVTRKDSGYYSLTAENSSGT 19906 Score = 35.9 bits (79), Expect = 6.7 Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 6/94 (6%) Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGT 188 +P G P P V W K+ L + +L+ I+DA + D G Y N+AG Sbjct: 23096 VPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAG- 23154 Query: 189 RESAIATLKIHI--KPYLITGPEDVVAQTGSSVT 220 AI TL + + KP TGP + T S+T Sbjct: 23155 --EAIETLNVIVLDKPGPPTGPVKMDEVTADSIT 23186 Score = 35.9 bits (79), Expect = 6.7 Identities = 35/144 (24%), Positives = 51/144 (35%), Gaps = 10/144 (6%) Query: 166 VIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED--------VVAQTGS 217 V+ R+ ++ A N AG + L + IK L D V + GS Sbjct: 27360 VVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGS 27419 Query: 218 SVTFQCRVGGDPLPDVLWRRSAGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAE 275 ++ + G PLP V R M ++ ++ L + AD G Y A Sbjct: 27420 NLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAA 27479 Query: 276 NSVGAVSASGYLTVYDPPSINLSP 299 NS G A + V D P P Sbjct: 27480 NSSGTTKAFINIVVLDRPGPPTGP 27503 Score = 35.5 bits (78), Expect = 8.9 Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 5/80 (6%) Query: 411 IKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVT--NDG--TLVLKDLDKSDSGTY 465 ++ M V F C P P IAWY +G+ + R + DG +L + + D G Y Sbjct: 1303 LEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIY 1362 Query: 466 TCVASSRHGKYVWSGALLVD 485 T AS+ G + SG L V+ Sbjct: 1363 TAFASNIKGNAICSGKLYVE 1382 Score = 35.5 bits (78), Expect = 8.9 Identities = 30/108 (27%), Positives = 44/108 (40%), Gaps = 11/108 (10%) Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562 +PGPP +V+ +TL+W G S + GY VE R+ + + WV Sbjct: 30858 IPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVE---RKEVRADR-------WVR 30907 Query: 563 IAR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 + + V T Y L G+ Y V N+ G PS S + D Sbjct: 30908 VNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMD 30955 Score = 35.5 bits (78), Expect = 8.9 Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 6/71 (8%) Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLV---DGGNLVIQDARQTDAGRYQCIARNAAGTRE 190 G P P V W G+ + R H+ D L+I D ++ D G Y N G Sbjct: 34281 GEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG--- 34337 Query: 191 SAIATLKIHIK 201 S AT+ IHI+ Sbjct: 34338 SDSATVNIHIR 34348 >UniRef50_Q4SHH6 Cluster: Chromosome 5 SCAF14581, whole genome shotgun sequence; n=2; Tetraodon nigroviridis|Rep: Chromosome 5 SCAF14581, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1515 Score = 141 bits (341), Expect = 1e-31 Identities = 178/754 (23%), Positives = 291/754 (38%), Gaps = 82/754 (10%) Query: 112 LEPESKQSAQGDTVVLECLPPRGSPEP-NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA 170 +EP+ + +G + L C + P V WKK+G + D R ++ G+L+ Sbjct: 15 VEPQDTLAFRGTSAQLNCSAHSDAATPARVEWKKDGTFMSPASDERRRILPDGSLLFTHV 74 Query: 171 -----RQTDAGRYQCIAR-NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR 224 + D G YQC+A G+ S A L + P + P GSS C Sbjct: 75 VHSKHNKPDEGTYQCVATIENLGSISSRTARLSVAGTPRFTSQPTAATVHQGSSHVMPCE 134 Query: 225 VGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSA 283 V D P W + + LG R+ L G+L + N D G Y C EN VG+ + Sbjct: 135 VNADLAPFARWEKDRQP--LELGARLIQLPSGALVISNASEGDAGLYRCLLEN-VGSSKS 191 Query: 284 SGYLTVYDPPSIN--------LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII 335 S ++ P L P SV G A C TG P P + W + G++ + Sbjct: 192 SDEAQLHVVPEPGQERKLEFLLEPVSVTKVLGATALLPCVVTGYPAPHVRWML-GDKLV- 249 Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD--- 392 + V G ++ N T+++ T + + N G+ + +L+V Sbjct: 250 -----EESEGRVEVLGGASLQISNLTEEDAGVYTCMADSAN--GTIEAQAQLSVQVGLVG 302 Query: 393 DDRP---PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND 449 + +P PP P+N VF C +P P + W G+A+I + + + Sbjct: 303 NIQPVGVPPQFVRRPANIYAHESMDIVFECEVSGSPAPSVKWVKNGDAVIPSDYFKIVKE 362 Query: 450 GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTK 509 L + L KSD G Y C+A + G S L++ + + A P P Sbjct: 363 HNLQVLGLVKSDEGFYQCLAENEAGNIQSSAQLIILDHGSGGV----ANTAGPTPSAPRD 418 Query: 510 PITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQ 569 + V+ + L+W + L Y V +S+E SR VV R + Sbjct: 419 LVASLVSTRFIKLTWRPPAEPHGDE-LTYSV-FYSQE--------GTSRERVVNTSRPGE 468 Query: 570 THYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNN 629 +++L+P Y F V NS+G G S S + V ++ + G + + + +N Sbjct: 469 MQVTIQNLMPDTKYRFRVLAHNSNG-QGES--SAAARVATQCRTVLQVPGPAPNLQAVSN 525 Query: 630 ILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDV 689 T + E TP + + + +L P+D + D Sbjct: 526 TPTSVSLSW-EKTPDRKRRHRHLQAVLRRQKRRQRAATKAPVDEPVCPLVQDVDV---DA 581 Query: 690 SGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDD-------------------- 729 +T L+K T+Y F ++ K G + +TL D Sbjct: 582 QSHTVTGLKKNTEYSFRVVANNKHGPGVSTEDVTVRTLSDGRWSNETTFGWIQQANVCSP 641 Query: 730 ---VPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN 786 VP PP N+ + + N+ ++ L+W PP QNG I Y + + +S + + Sbjct: 642 SSTVPSAPPQNLTLEVQNSKSIMLRWQPPPPSSQNGEIINYKIKYR---KGSRRSETSDS 698 Query: 787 TTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGP 820 T+ Q LI + L G YS +++A T+ G GP Sbjct: 699 TSGSQLFKLI-SGLERGTEYSFRVSAMTVNGTGP 731 Score = 126 bits (303), Expect = 5e-27 Identities = 85/295 (28%), Positives = 134/295 (45%), Gaps = 22/295 (7%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P QP TV + + C +P RW K + LP+G L A Sbjct: 112 PRFTSQPTAATVHQGSSHVMPCEVNADLAPFARWEKDRQPLELGARLIQLPSGALVISNA 171 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVA-----VLREEFRLEPESKQSAQGDTVV 126 + G DAG+Y C N + S A LHV + EF LEP S G T + Sbjct: 172 SEG----DAGLYRCLLENVGSSKSSDEAQLHVVPEPGQERKLEFLLEPVSVTKVLGATAL 227 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186 L C+ G P P+V W G L+ + + R+ ++ G +L I + + DAG Y C+A +A Sbjct: 228 LPCV-VTGYPAPHVRWML-GDKLVEESEGRVEVLGGASLQISNLTEEDAGVYTCMADSAN 285 Query: 187 GTRES---------AIATLK-IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 GT E+ + ++ + + P + P ++ A + F+C V G P P V W Sbjct: 286 GTIEAQAQLSVQVGLVGNIQPVGVPPQFVRRPANIYAHESMDIVFECEVSGSPAPSVKWV 345 Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291 ++ G +P K++ + +L++ ++ +DEG Y C AEN G + +S L + D Sbjct: 346 KN-GDAVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCLAENEAGNIQSSAQLIILD 399 Score = 63.7 bits (148), Expect = 3e-08 Identities = 75/305 (24%), Positives = 123/305 (40%), Gaps = 27/305 (8%) Query: 203 YLITGPEDVVAQTGSSVTFQCRVGGDPLPD--VLWRRSAGGGNMPLG--RVKVLDDGSLR 258 +L P+D +A G+S C D V W++ G P R ++L DGSL Sbjct: 12 WLTVEPQDTLAFRGTSAQLNCSAHSDAATPARVEWKKD-GTFMSPASDERRRILPDGSLL 70 Query: 259 LDNVILA-----DEGEYSCEAE-NSVGAVSA-SGYLTVYDPPSINLSPNSVNVESGNVAR 311 +V+ + DEG Y C A ++G++S+ + L+V P P + V G+ Sbjct: 71 FTHVVHSKHNKPDEGTYQCVATIENLGSISSRTARLSVAGTPRFTSQPTAATVHQGSSHV 130 Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371 C P W E +R + G + + A L I++ + D+ Sbjct: 131 MPCEVNADLAPFARW--EKDRQPLELGARLIQLPSGA-------LVISNASEGDA-GLYR 180 Query: 372 CSAVNYAGS-SFVRGKLTVTSDDDRPPPI-ITNGPSNQTLPIKSMAVFPCTAICTPEPII 429 C N S S +L V + + + P + T + + A+ PC P P + Sbjct: 181 CLLENVGSSKSSDEAQLHVVPEPGQERKLEFLLEPVSVTKVLGATALLPCVVTGYPAPHV 240 Query: 430 AWYFEGEALIQNH--RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 W G+ L++ R V +L + +L + D+G YTC+A S +G L V Sbjct: 241 RWML-GDKLVEESEGRVEVLGGASLQISNLTEEDAGVYTCMADSANGTIEAQAQLSVQVG 299 Query: 488 INPNI 492 + NI Sbjct: 300 LVGNI 304 Score = 52.0 bits (119), Expect = 1e-04 Identities = 51/204 (25%), Positives = 84/204 (41%), Gaps = 13/204 (6%) Query: 639 IEATPIDSKTIKLMWEILNFYYLEGL----FIYFRPLDNITIEYEMKTILHSNDVS-GFE 693 ++A+ + TIK+ W + + + F R NI ++K +N S + Sbjct: 887 VQASVLSHDTIKVSWADNTLHKSQKITDNRFYTVRWKTNIPANTKVKM---ANTTSLNYM 943 Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTT--TVHLK 751 +T L+ T YEF ++ + S + T + VP P ++ + T+ + Sbjct: 944 VTGLKPNTLYEFSVMLTRGRRTSTWSMTAQGTTFEAVPSSSPKDVTVVSKENKPRTIIIN 1003 Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811 W PP NG ITGY ++ DV A I V + + LT +Y +I Sbjct: 1004 WQPPSEA--NGKITGY-IIYYSTDVNAEDHDWVIEPVVGNRLTHQIQELTLDTTYYFKIQ 1060 Query: 812 AETIIGLGPFSQKVYFNIDSRSVG 835 A G+GP S+ V+F R G Sbjct: 1061 ARNSKGMGPMSEAVHFRTPKRPSG 1084 Score = 50.0 bits (114), Expect = 4e-04 Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 4/88 (4%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68 G P + +P ++ C GSP+P+++W K G V+ + I+ L Sbjct: 308 GVPPQFVRRPANIYAHESMDIVFECEVSGSPAPSVKWVKNGDAVIPSDYFKIVKEHNLQV 367 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARS 96 L G V SD G Y C A N G +S Sbjct: 368 L----GLVKSDEGFYQCLAENEAGNIQS 391 >UniRef50_UPI00004D93F2 Cluster: immunoglobulin superfamily, member 10; n=3; Xenopus tropicalis|Rep: immunoglobulin superfamily, member 10 - Xenopus tropicalis Length = 2566 Score = 140 bits (340), Expect = 2e-31 Identities = 130/481 (27%), Positives = 199/481 (41%), Gaps = 39/481 (8%) Query: 22 TVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80 TV + A + C A G+PSP I W K VS T R + + D Sbjct: 1602 TVLANSDAFIPCEASGNPSPTILWTKVSSGTFVSKTRRVNKMEVFMNGTLSIPSVGIQDG 1661 Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA--QGDTVVLECLPPRGSPEP 138 G Y C A N G+ R TL V L+ S++ G++V + C GSP P Sbjct: 1662 GQYLCVANNQLGSDRLL-VTLSVITYPPRI-LQGRSREITVHSGNSVNVNC-QAEGSPFP 1718 Query: 139 NVYWKKNGQTLLF---DGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195 + W +T+ F + ++ + G L+I+D D G Y+C+A N AG + Sbjct: 1719 TITWTLKNETIPFGTSTSNRKIFVQPDGTLIIKDVTVYDRGIYRCLATNLAGEDTFTVRI 1778 Query: 196 LKIHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL----GRVK 250 I P ++ + V+A G ++ C G+P P V W G PL ++ Sbjct: 1779 QVIAAPPVIVEEKRQTVLAGPGENLKIPCTAKGNPQPTVHWVAFDGTKIKPLQYVNAKLF 1838 Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD----PPSINLSPNSVNVES 306 + +G+L + NV D G Y C A +S G+ L V P + SP + + Sbjct: 1839 LFSNGTLYIRNVASTDRGNYECIATSSTGSERRVVNLIVEQSDTFPKITDASPKATEMNF 1898 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG-VTVLTINDTDKND 365 G+ CTATG P+P + W + + + R +G + V ++ND D D Sbjct: 1899 GDKLMLNCTATGEPKPRIIWRLPSKAVV--DQLHRMGSRIQVFPNGTLFVDSVNDKDAGD 1956 Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425 +C A N G + K++VT +P II P + +P C A +P Sbjct: 1957 ----YLCVARNKMGDDVILMKVSVTM---KPAKIIQKQPLAKQVPYGKDFKVDCKASGSP 2009 Query: 426 EPIIAWYFEGEALIQN----------HRRNVTND-GTLVLKDLDKSDSGTYTCVASSRHG 474 P I+W +I N RR + D GTL L + ++ G YTC A ++ G Sbjct: 2010 LPDISWSLPDGTMINNILQADDSGRRKRRYILFDNGTLYLNKVGIAEEGDYTCYAENQLG 2069 Query: 475 K 475 + Sbjct: 2070 R 2070 Score = 126 bits (305), Expect = 3e-27 Identities = 123/480 (25%), Positives = 205/480 (42%), Gaps = 38/480 (7%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV---VSDTHRSIL--PAGGLFFLRATHG 74 ++TV +NC+A GSP P I W + S ++R I P G L T Sbjct: 1697 EITVHSGNSVNVNCQAEGSPFPTITWTLKNETIPFGTSTSNRKIFVQPDGTLIIKDVT-- 1754 Query: 75 RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA---QGDTVVLECLP 131 V+ D G+Y C ATN G T+ + V+ + E +Q+ G+ + + C Sbjct: 1755 -VY-DRGIYRCLATNLAG---EDTFTVRIQVIAAPPVIVEEKRQTVLAGPGENLKIPCTA 1809 Query: 132 PRGSPEPNVYWKK-NGQTL--LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188 +G+P+P V+W +G + L ++++ L G L I++ TD G Y+CIA ++ G+ Sbjct: 1810 -KGNPQPTVHWVAFDGTKIKPLQYVNAKLFLFSNGTLYIRNVASTDRGNYECIATSSTGS 1868 Query: 189 RESAIATLKIHIKPY-LIT--GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 + + + IT P+ G + C G+P P ++WR + Sbjct: 1869 ERRVVNLIVEQSDTFPKITDASPKATEMNFGDKLMLNCTATGEPKPRIIWRLPSKAVVDQ 1928 Query: 246 L----GRVKVLDDGSLRLDNVILADEGEYSCEAENSVG--AVSASGYLTVYDPPSINLSP 299 L R++V +G+L +D+V D G+Y C A N +G + +T+ I P Sbjct: 1929 LHRMGSRIQVFPNGTLFVDSVNDKDAGDYLCVARNKMGDDVILMKVSVTMKPAKIIQKQP 1988 Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSV-EGN--RTIIFPGMSRDKYHATAVFDGVTVL 356 + V G + C A+G P P + WS+ +G I+ S + +FD T L Sbjct: 1989 LAKQVPYGKDFKVDCKASGSPLPDISWSLPDGTMINNILQADDSGRRKRRYILFDNGT-L 2047 Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416 +N + C A N G ++ +TV + P I N + + Sbjct: 2048 YLNKVGIAE-EGDYTCYAENQLGRDEMKVHITVVT---AAPLIKLNMKTRYAAMAGESVI 2103 Query: 417 FPCTAICTPEPIIAWYFEGEALIQ-NHRRNVTND-GTLVLKDLDKSDSGTYTCVASSRHG 474 C A P+P I W +I +H R + ++ G+L + + D+G Y CVA + G Sbjct: 2104 LDCEANGEPKPKIFWLLPSSDMIAISHDRYLLHENGSLTVSQVKLLDAGEYMCVARNPAG 2163 Score = 126 bits (305), Expect = 3e-27 Identities = 126/500 (25%), Positives = 207/500 (41%), Gaps = 48/500 (9%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK------GGVLVVSDT--- 56 VT A I +QPL V + ++C+A GSP P I W +L D+ Sbjct: 1976 VTMKPAKIIQKQPLAKQVPYGKDFKVDCKASGSPLPDISWSLPDGTMINNILQADDSGRR 2035 Query: 57 -HRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE--FRLE 113 R IL G +L ++ G Y C A N G + +H+ V+ +L Sbjct: 2036 KRRYILFDNGTLYLNKVG---IAEEGDYTCYAENQLGRDEMK---VHITVVTAAPLIKLN 2089 Query: 114 PESKQSAQ-GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ 172 +++ +A G++V+L+C G P+P ++W ++ R L + G+L + + Sbjct: 2090 MKTRYAAMAGESVILDC-EANGEPKPKIFWLLPSSDMIAISHDRYLLHENGSLTVSQVKL 2148 Query: 173 TDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG---PEDVVAQTG---SSVTFQCRVG 226 DAG Y C+ARN AG ++ + L++H KP +I G + ++ T S C+ Sbjct: 2149 LDAGEYMCVARNPAGD-DTKLLRLEVHPKPPIINGLYSNKSIIKDTAIKHSRKLIDCKAE 2207 Query: 227 GDPLPDVLWRRSAG---GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSA 283 G V+W R+ V +G+L + N+ +D E++C A N G Sbjct: 2208 GAAPLQVMWIMPDNIYLTAPYHGSRILVHQNGTLEIRNIRPSDTAEFTCVARNDGGESML 2267 Query: 284 SGYLTVYDPPSINLSPNSVN----VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGM 339 L V + + N N +S +A C A G P P + W + N T G Sbjct: 2268 VVQLEVLEMLRRPMFKNPFNEKFIAKSSKMAILNCFAEGNPTPEIIWLLP-NGTRFLNGP 2326 Query: 340 SRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPI 399 S KYHA + +G ++ + D C+A N G ++ KL + + + P I Sbjct: 2327 SISKYHAGS--NGTFIIY---SPTKDDAGKYRCAARNKVG--YIE-KLIIL-EVGQKPNI 2377 Query: 400 ITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ----NHRRNVTNDGTLVLK 455 +T+ I C + P P + W I+ R + +GTLV++ Sbjct: 2378 LTHPRGPIKSIIGEALSLHCLSDGMPRPSVTWILPSGYAIERPQVQGRYKLLENGTLVIQ 2437 Query: 456 DLDKSDSGTYTCVASSRHGK 475 + D G Y C A + G+ Sbjct: 2438 ETALHDRGNYQCKAKNYAGE 2457 Score = 126 bits (305), Expect = 3e-27 Identities = 96/381 (25%), Positives = 160/381 (41%), Gaps = 21/381 (5%) Query: 22 TVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTH--RSILPAGGLFFLRATHGRVHS 78 T +H ++C+A G+ + W + + + H R ++ G +R S Sbjct: 2193 TAIKHSRKLIDCKAEGAAPLQVMWIMPDNIYLTAPYHGSRILVHQNGTLEIRNIRP---S 2249 Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ--SAQGDTVVLECLPPRGSP 136 D + C A N G + + +LR P +++ + +L C G+P Sbjct: 2250 DTAEFTCVARNDGGESMLVVQLEVLEMLRRPMFKNPFNEKFIAKSSKMAILNCFA-EGNP 2308 Query: 137 EPNVYWKKNGQTLLFDGDS--RMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194 P + W T +G S + H G +I + DAG+Y+C ARN G E I Sbjct: 2309 TPEIIWLLPNGTRFLNGPSISKYHAGSNGTFIIYSPTKDDAGKYRCAARNKVGYIEKLII 2368 Query: 195 TLKIHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGG-NMPL--GRVK 250 L++ KP ++T P + G +++ C G P P V W +G P GR K Sbjct: 2369 -LEVGQKPNILTHPRGPIKSIIGEALSLHCLSDGMPRPSVTWILPSGYAIERPQVQGRYK 2427 Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVG--AVSASGYLTVYDPPSINLSPNSVNVESGN 308 +L++G+L + L D G Y C+A+N G A++ + + Y P N P +++ +G+ Sbjct: 2428 LLENGTLVIQETALHDRGNYQCKAKNYAGETAITVTVVVVAYPPRITNKPPQTIHTRAGS 2487 Query: 309 VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368 R C A G P+P +FW + + S+ T + L I + +DS Sbjct: 2488 AVRLNCMAIGIPKPDIFWELPD--LSVLSTASQGSLTGTELLHPQGTLVIQNPQSSDS-G 2544 Query: 369 TIVCSAVNYAGSSFVRGKLTV 389 C A N G+ + L V Sbjct: 2545 IYKCIAKNSLGTDMSKTYLNV 2565 Score = 109 bits (262), Expect = 5e-22 Identities = 122/469 (26%), Positives = 200/469 (42%), Gaps = 42/469 (8%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTH-RSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89 L+C A G P P I W +++ +H R +L G L + ++ DAG Y C A N Sbjct: 2104 LDCEANGEPKPKIFWLLPSSDMIAISHDRYLLHENGS--LTVSQVKL-LDAGEYMCVARN 2160 Query: 90 SYGT-ARSRNATLHVA--VLREEFRLEPESKQSA-QGDTVVLECLPPRGSPEPNVYWKKN 145 G + +H ++ + + K +A + +++C G+ V W Sbjct: 2161 PAGDDTKLLRLEVHPKPPIINGLYSNKSIIKDTAIKHSRKLIDC-KAEGAAPLQVMWIMP 2219 Query: 146 GQTLL---FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA--TLKIHI 200 L + G SR+ + G L I++ R +D + C+ARN G + L++ Sbjct: 2220 DNIYLTAPYHG-SRILVHQNGTLEIRNIRPSDTAEFTCVARNDGGESMLVVQLEVLEMLR 2278 Query: 201 KPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG--NMP-LGRVKVLDDG 255 +P + P E +A++ C G+P P+++W G N P + + +G Sbjct: 2279 RP-MFKNPFNEKFIAKSSKMAILNCFAEGNPTPEIIWLLPNGTRFLNGPSISKYHAGSNG 2337 Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS-VNVESGNVARFTC 314 + + + D G+Y C A N VG + L V P+I P + G C Sbjct: 2338 TFIIYSPTKDDAGKYRCAARNKVGYIEKLIILEVGQKPNILTHPRGPIKSIIGEALSLHC 2397 Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374 + G P P++ W + I P + + +Y + + T L I +T +D R C A Sbjct: 2398 LSDGMPRPSVTWILPSGYAIERPQV-QGRYK---LLENGT-LVIQETALHD-RGNYQCKA 2451 Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK--SMAVFPCTAICTPEPIIAWY 432 NYAG + + TVT PP ITN P QT+ + S C AI P+P I W Sbjct: 2452 KNYAGETAI----TVTVVVVAYPPRITNKPP-QTIHTRAGSAVRLNCMAIGIPKPDIFWE 2506 Query: 433 FEGEALIQNHRR-NVTN------DGTLVLKDLDKSDSGTYTCVASSRHG 474 +++ + ++T GTLV+++ SDSG Y C+A + G Sbjct: 2507 LPDLSVLSTASQGSLTGTELLHPQGTLVIQNPQSSDSGIYKCIAKNSLG 2555 Score = 105 bits (253), Expect = 6e-21 Identities = 86/301 (28%), Positives = 139/301 (46%), Gaps = 24/301 (7%) Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTF-QCRVGGDPLPDVLWRRSAGGGNMP- 245 T ++ +T KP +I G +S F C G+P P +LW + + G + Sbjct: 1577 TVSTSFSTQNSRSKPRIIGGKAASFTVLANSDAFIPCEASGNPSPTILWTKVSSGTFVSK 1636 Query: 246 ---LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV--YDPPSINLSPN 300 + +++V +G+L + +V + D G+Y C A N +G+ L+V Y P + Sbjct: 1637 TRRVNKMEVFMNGTLSIPSVGIQDGGQYLCVANNQLGSDRLLVTLSVITYPPRILQGRSR 1696 Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360 + V SGN C A G P PT+ W+++ N TI F G S DG L I D Sbjct: 1697 EITVHSGNSVNVNCQAEGSPFPTITWTLK-NETIPF-GTSTSNRKIFVQPDG--TLIIKD 1752 Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL--PIKSMAVFP 418 D R C A N AG ++ V + PP+I L P +++ + P Sbjct: 1753 VTVYD-RGIYRCLATNLAGEDTFTVRIQVIA----APPVIVEEKRQTVLAGPGENLKI-P 1806 Query: 419 CTAICTPEPIIAWY-FEGEAL--IQ--NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473 CTA P+P + W F+G + +Q N + + ++GTL ++++ +D G Y C+A+S Sbjct: 1807 CTAKGNPQPTVHWVAFDGTKIKPLQYVNAKLFLFSNGTLYIRNVASTDRGNYECIATSST 1866 Query: 474 G 474 G Sbjct: 1867 G 1867 Score = 61.3 bits (142), Expect = 2e-07 Identities = 72/267 (26%), Positives = 110/267 (41%), Gaps = 18/267 (6%) Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360 S V + + A C A+G P PT+ W+ + T F +R + + VF T L+I Sbjct: 1600 SFTVLANSDAFIPCEASGNPSPTILWTKVSSGT--FVSKTR-RVNKMEVFMNGT-LSIPS 1655 Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ-TLPIKSMAVFPC 419 D +C A N GS +L VT PP I G S + T+ + C Sbjct: 1656 VGIQDG-GQYLCVANNQLGSD----RLLVTLSVITYPPRILQGRSREITVHSGNSVNVNC 1710 Query: 420 TAICTPEPIIAWYFEGEAL-----IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 A +P P I W + E + N + V DGTL++KD+ D G Y C+A++ G Sbjct: 1711 QAEGSPFPTITWTLKNETIPFGTSTSNRKIFVQPDGTLIIKDVTVYDRGIYRCLATNLAG 1770 Query: 475 KYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSW--SQNNKIGS 532 + ++ + V + P I + V + PG K + T+ W KI Sbjct: 1771 EDTFTVRIQVIA-APPVIVEEKRQTVLAGPGENLKIPCTAKGNPQPTVHWVAFDGTKIKP 1829 Query: 533 SSILGYQVEVFSRETLSGNNTPRNSRG 559 + ++ +FS TL N RG Sbjct: 1830 LQYVNAKLFLFSNGTLYIRNVASTDRG 1856 Score = 57.2 bits (132), Expect = 3e-06 Identities = 45/163 (27%), Positives = 71/163 (43%), Gaps = 11/163 (6%) Query: 31 LNCRAGGSPSPAIRWY-----KGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85 ++C G P+PAI W K S R + G F L++ + D G+Y C Sbjct: 492 MDCEVLGEPTPAIEWILPDGSKIRAPYASQEGRITITKNGKFILKSAD---NFDTGIYHC 548 Query: 86 EATNSYGT-ARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK 144 ATN S T+ + + E+F E S GD + L C G P+ +V W Sbjct: 549 IATNYIDADVLSFRITVVSSDVEEQFVNGVELSVS-NGDYINLPC-GSSGVPDASVSWIL 606 Query: 145 NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 ++L++ ++ G L IQ + D+G ++C+A N G Sbjct: 607 PDHSVLYEPSRNKIILANGTLKIQGISERDSGHFRCLAANQYG 649 Score = 54.0 bits (124), Expect = 2e-05 Identities = 41/180 (22%), Positives = 75/180 (41%), Gaps = 9/180 (5%) Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 G C G P P + W + I P S++ T +G +L D N Sbjct: 487 GGTVEMDCEVLGEPTPAIEWILPDGSKIRAPYASQEG-RITITKNGKFILKSAD---NFD 542 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426 C A NY + + ++TV S D NG ++ PC + P+ Sbjct: 543 TGIYHCIATNYIDADVLSFRITVVSSDVEEQ--FVNGVE-LSVSNGDYINLPCGSSGVPD 599 Query: 427 PIIAWYFEGEALIQNHRRN--VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 ++W +++ RN + +GTL ++ + + DSG + C+A++++G + + +LV Sbjct: 600 ASVSWILPDHSVLYEPSRNKIILANGTLKIQGISERDSGHFRCLAANQYGLDILTHRVLV 659 Score = 49.2 bits (112), Expect = 7e-04 Identities = 41/165 (24%), Positives = 65/165 (39%), Gaps = 9/165 (5%) Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTL---LFDGDSRMHLVDGGNLVIQDARQTDAGR 177 G TV ++C G P P + W +G + + R+ + G +++ A D G Sbjct: 487 GGTVEMDC-EVLGEPTPAIEWILPDGSKIRAPYASQEGRITITKNGKFILKSADNFDTGI 545 Query: 178 YQCIARNA--AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235 Y CIA N A I + ++ + G E V+ G + C G P V W Sbjct: 546 YHCIATNYIDADVLSFRITVVSSDVEEQFVNGVELSVSN-GDYINLPCGSSGVPDASVSW 604 Query: 236 RRSAGGGNMPLGRVKV-LDDGSLRLDNVILADEGEYSCEAENSVG 279 R K+ L +G+L++ + D G + C A N G Sbjct: 605 ILPDHSVLYEPSRNKIILANGTLKIQGISERDSGHFRCLAANQYG 649 Score = 45.2 bits (102), Expect = 0.011 Identities = 34/136 (25%), Positives = 56/136 (41%), Gaps = 7/136 (5%) Query: 213 AQTGSSVTFQCRVGGDPLPDVLWRRSAGGG-NMPL----GRVKVLDDGSLRLDNVILADE 267 A G +V C V G+P P + W G P GR+ + +G L + D Sbjct: 484 AVIGGTVEMDCEVLGEPTPAIEWILPDGSKIRAPYASQEGRITITKNGKFILKSADNFDT 543 Query: 268 GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV--NVESGNVARFTCTATGRPEPTMF 325 G Y C A N + A S +TV N V +V +G+ C ++G P+ ++ Sbjct: 544 GIYHCIATNYIDADVLSFRITVVSSDVEEQFVNGVELSVSNGDYINLPCGSSGVPDASVS 603 Query: 326 WSVEGNRTIIFPGMSR 341 W + + + P ++ Sbjct: 604 WILPDHSVLYEPSRNK 619 >UniRef50_UPI0000DB6D93 Cluster: PREDICTED: similar to CG32387-PB, isoform B; n=3; Apocrita|Rep: PREDICTED: similar to CG32387-PB, isoform B - Apis mellifera Length = 792 Score = 138 bits (335), Expect = 6e-31 Identities = 111/371 (29%), Positives = 167/371 (45%), Gaps = 38/371 (10%) Query: 122 GDTVVLECLPPRGSPEPNVYWKKN---GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY 178 G+T+VL C+ +G P P W + G ++F+ + R++ G LV+Q AR DAGRY Sbjct: 204 GETIVLSCIS-QGIPPPMYLWFRESVTGTAMIFNSE-RIY-ARAGVLVLQSARAEDAGRY 260 Query: 179 QCIARNAAGTRE-----SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233 C A N AG+ S I++L IH+ P + V G FQC V G P+P + Sbjct: 261 VCHANNTAGSEMVELEVSIISSLSIHLVP------QQVTVDLGKDAEFQCSVTGQPIPVI 314 Query: 234 LWRRSA-GGGNMPLGRVKVL-DDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290 W + G GR K+ +DGS LR+ +V+ D+G Y C A+N V A+ L + Sbjct: 315 FWTKDGLPVGESASGRSKITGNDGSTLRISSVVRDDKGMYQCFAKNDYEMVQATAELRLG 374 Query: 291 DP-PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY----H 345 D P + ++ G C ATG P P W+++G FP D++ + Sbjct: 375 DAAPQLLYKFIEQTIQPGPSVSLKCIATGNPTPHFSWTLDG-----FPLPQNDRFMIGQY 429 Query: 346 ATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPS 405 T D ++ + I+ D C+A N +L + P + G Sbjct: 430 VTVHGDVISHVNISVVHVEDG-GEYRCTAANRMAKVHHSARLNIYG----LPHVRPMG-- 482 Query: 406 NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS-DSGT 464 N V C P I W +G+ L + R+ V +GTLVL +D+S D G Sbjct: 483 NYAAVAGETTVIKCPVAGFPIASITWEKDGKVLPTSRRQEVFPNGTLVLHHVDRSTDHGA 542 Query: 465 YTCVASSRHGK 475 YTC A ++ G+ Sbjct: 543 YTCTAKNKQGR 553 Score = 128 bits (309), Expect = 9e-28 Identities = 131/480 (27%), Positives = 200/480 (41%), Gaps = 39/480 (8%) Query: 31 LNCRAGGSPSPAIRWYKGGVL-VVSDTH-RSILPAGGLFFLR--ATHGRVHSDAGVYWCE 86 ++C A GSP P I W G V+ H R +L G ++FL A R + VY C+ Sbjct: 2 IHCSAQGSPLPRIDWLMGDESPVLPIPHIREMLVNGSMYFLPFGAETYRHDVHSAVYRCQ 61 Query: 87 ATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE--PNVYWKK 144 A+NS G R T+ AV+R+++ ++ G+T VL C P E W + Sbjct: 62 ASNSVGRVLGREITVK-AVVRQKYEVQVRDAYVLPGNTGVLRCEIPTFVKEYVAVTSWVR 120 Query: 145 NGQTLLFD---GDSRMHLVDGGNLVIQDARQTDA-GRYQC--IARNAAGTRESAIATLKI 198 + +F D R H++ G L++ +DA Y+C + R T ES+ + Sbjct: 121 DSAYNIFPTPKSDDRHHMLPTGELLVFSVTSSDAQSSYRCRTVHRVTGDTVESSSYARLV 180 Query: 199 HIKPYLITGPE------DVVAQTGSSVTFQCRVGGDPLPDVLW-RRSAGGGNMPLGRVKV 251 P+ P +TG ++ C G P P LW R S G M ++ Sbjct: 181 VTDPHTPVPPRFNERVSPAPIRTGETIVLSCISQGIPPPMYLWFRESVTGTAMIFNSERI 240 Query: 252 LDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310 G L L + D G Y C A N+ G+ +++ SI+L P V V+ G A Sbjct: 241 YARAGVLVLQSARAEDAGRYVCHANNTAGSEMVELEVSIISSLSIHLVPQQVTVDLGKDA 300 Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370 F C+ TG+P P +FW+ +G + G S DG T L I+ ++D + Sbjct: 301 EFQCSVTGQPIPVIFWTKDG----LPVGESASGRSKITGNDGST-LRISSVVRDD-KGMY 354 Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA 430 C A N +L + D P ++ P S+++ C A P P + Sbjct: 355 QCFAKNDYEMVQATAELRL---GDAAPQLLYKFIEQTIQPGPSVSL-KCIATGNPTPHFS 410 Query: 431 WYFEGEALIQNHR----RNVTNDGTLV----LKDLDKSDSGTYTCVASSRHGKYVWSGAL 482 W +G L QN R + VT G ++ + + D G Y C A++R K S L Sbjct: 411 WTLDGFPLPQNDRFMIGQYVTVHGDVISHVNISVVHVEDGGEYRCTAANRMAKVHHSARL 470 Score = 111 bits (268), Expect = 8e-23 Identities = 128/497 (25%), Positives = 197/497 (39%), Gaps = 47/497 (9%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG---GVLVVSDTHRSILPAGGLFF 68 P E+ + + L+C + G P P W++ G ++ ++ R I G+ Sbjct: 190 PRFNERVSPAPIRTGETIVLSCISQGIPPPMYLWFRESVTGTAMIFNSER-IYARAGVLV 248 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVL 127 L++ DAG Y C A N TA S L V+++ L P+ G Sbjct: 249 LQSARAE---DAGRYVCHANN---TAGSEMVELEVSIISSLSIHLVPQQVTVDLGKDAEF 302 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV--DGGNLVIQDARQTDAGRYQCIARNA 185 +C G P P ++W K+G + R + DG L I + D G YQC A+N Sbjct: 303 QC-SVTGQPIPVIFWTKDGLPVGESASGRSKITGNDGSTLRISSVVRDDKGMYQCFAKND 361 Query: 186 AGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA----G 240 + A A L++ P L+ + Q G SV+ +C G+P P W Sbjct: 362 YEMVQ-ATAELRLGDAAPQLLYKFIEQTIQPGPSVSLKCIATGNPTPHFSWTLDGFPLPQ 420 Query: 241 GGNMPLGR-VKVLDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297 +G+ V V D + + V + D GEY C A N + V S L +Y P + Sbjct: 421 NDRFMIGQYVTVHGDVISHVNISVVHVEDGGEYRCTAANRMAKVHHSARLNIYGLPHVRP 480 Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 N V +G C G P ++ W +G + P R + VF T L Sbjct: 481 MGNYAAV-AGETTVIKCPVAGFPIASITWEKDGK---VLPTSRRQE-----VFPNGT-LV 530 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT-NGPSNQTLPIKSMAV 416 ++ D++ C+A N G S TV + PP I + P+N + V Sbjct: 531 LHHVDRSTDHGAYTCTAKNKQGRS---DSQTVHIEVKVPPKIDPFSFPANIQEGARVHVV 587 Query: 417 FPCTAICTPEPI-IAWYFEGEALIQNHRRNVTN-----DGTLVLKDLDKSDSGTYTCVAS 470 C P+ I W +G L N T+ D TL+++ + +G YTCVAS Sbjct: 588 --CVVSEGDSPLKITWLKDGRPL--NSTETTTHHIGEYDLTLMIQSATTAHNGNYTCVAS 643 Query: 471 SRHGKYVWSGALLVDSP 487 + + + +LLV P Sbjct: 644 NDAAETSRTASLLVHVP 660 Score = 95.9 bits (228), Expect = 6e-18 Identities = 85/330 (25%), Positives = 136/330 (41%), Gaps = 17/330 (5%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI---LPAGGLF 67 AP ++ + ++ T+ +L C A G+P+P W G + + I + G Sbjct: 377 APQLLYKFIEQTIQPGPSVSLKCIATGNPTPHFSWTLDGFPLPQNDRFMIGQYVTVHGDV 436 Query: 68 FLRATHGRVH-SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTV 125 VH D G Y C A N +A L++ L + P +A G+T Sbjct: 437 ISHVNISVVHVEDGGEYRCTAANRMAKVH-HSARLNIYGLPH---VRPMGNYAAVAGETT 492 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA-RQTDAGRYQCIARN 184 V++C P G P ++ W+K+G+ L R + G LV+ R TD G Y C A+N Sbjct: 493 VIKC-PVAGFPIASITWEKDGKVL--PTSRRQEVFPNGTLVLHHVDRSTDHGAYTCTAKN 549 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGN 243 G +S +++ + P + Q G+ V C V GD + W + N Sbjct: 550 KQGRSDSQTVHIEVKVPPKIDPFSFPANIQEGARVHVVCVVSEGDSPLKITWLKDGRPLN 609 Query: 244 MPLGRVKVLD--DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301 + D +L + + A G Y+C A N S + L V+ PP+I + Sbjct: 610 STETTTHHIGEYDLTLMIQSATTAHNGNYTCVASNDAAETSRTASLLVHVPPTIAPFSFN 669 Query: 302 VNVESGNVARFTC-TATGRPEPTMFWSVEG 330 ++ G A+ TC G P T+ WS +G Sbjct: 670 KDLSEGVRAQVTCMVEKGDPPFTIAWSKDG 699 Score = 95.5 bits (227), Expect = 8e-18 Identities = 126/504 (25%), Positives = 202/504 (40%), Gaps = 56/504 (11%) Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRV 76 P VTV + A C G P P I W K G+ V S + RS + LR + V Sbjct: 289 PQQVTVDLGKDAEFQCSVTGQPIPVIFWTKDGLPVGESASGRSKITGNDGSTLRIS-SVV 347 Query: 77 HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136 D G+Y C A N Y ++ A L + + + + G +V L+C+ G+P Sbjct: 348 RDDKGMYQCFAKNDYEMVQA-TAELRLGDAAPQLLYKFIEQTIQPGPSVSLKCI-ATGNP 405 Query: 137 EPNVYWKKNGQTLLFDGDSRM---HLVDGGNLV----IQDARQTDAGRYQCIARNAAGTR 189 P+ W +G L D M ++ G+++ I D G Y+C A N Sbjct: 406 TPHFSWTLDGFPLP-QNDRFMIGQYVTVHGDVISHVNISVVHVEDGGEYRCTAANRMAKV 464 Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-R 248 + A L I+ P+ + + A G + +C V G P+ + W + G +P R Sbjct: 465 HHS-ARLNIYGLPH-VRPMGNYAAVAGETTVIKCPVAGFPIASITWEKD--GKVLPTSRR 520 Query: 249 VKVLDDGSLRLDNVILA-DEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSPNSVNVES 306 +V +G+L L +V + D G Y+C A+N G + S + ++ V PP I+ N++ Sbjct: 521 QEVFPNGTLVLHHVDRSTDHGAYTCTAKNKQGRSDSQTVHIEVKVPPKIDPFSFPANIQE 580 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 G C + P ++ R + + H +D +T++ + T ++ Sbjct: 581 GARVHVVCVVSEGDSPLKITWLKDGRPL---NSTETTTHHIGEYD-LTLMIQSATTAHNG 636 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426 T C A N A + L V PP I N+ L A C Sbjct: 637 NYT--CVASNDAAETSRTASLLV-----HVPPTIAPFSFNKDLSEGVRAQVTCMVEKGDP 689 Query: 427 PI-IAWYFEGEAL--------------IQNHRR-------NVTN----DGTLVLKDLDKS 460 P IAW +GEA+ I R VTN T+V++ + + Sbjct: 690 PFTIAWSKDGEAIAGPSPAAAGFGNTGITGPRHTQTPAGLRVTNIDAHSSTIVIERVSAA 749 Query: 461 DSGTYTCVASSRHGKYVWSGALLV 484 SG YTC+A + + +W+ L+V Sbjct: 750 HSGNYTCMARNSVAEVLWTAELIV 773 >UniRef50_O97394 Cluster: Protein sidekick precursor; n=9; Endopterygota|Rep: Protein sidekick precursor - Drosophila melanogaster (Fruit fly) Length = 2224 Score = 138 bits (334), Expect = 9e-31 Identities = 190/756 (25%), Positives = 297/756 (39%), Gaps = 74/756 (9%) Query: 39 PSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRN 98 P P++ W + D + A L L A +D Y +A N+ + Sbjct: 189 PVPSVMWQSEDGPLNYDIKYAFTHANQLIILSADE----NDRKGYRAKAINTQLGKEESS 244 Query: 99 ATLHVAV-------LREEFRLEPESKQSAQGDTVV-LECLP-PRGSPEPNVYWKKNGQTL 149 A +H+ V + E + P+ + G VV L+C+ R E W K+G + Sbjct: 245 AFVHLNVSGDPYIEVAPEIIVRPQDVKVKVGTGVVELQCIANARPLHELETLWLKDGLAV 304 Query: 150 LFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI-KPYLIT 206 G R L D N L + A + +G Y C R +G + A+ ++ I +P L Sbjct: 305 ETAG-VRHTLNDPWNRTLALLQANSSHSGEYTCQVRLRSGGYPAVSASARLQILEPPLFF 363 Query: 207 GP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPLGRVKVLDDGSLRLDNV 262 P + + G V C V G+P P V W R+A ++ GR + D +L + + Sbjct: 364 TPMRAETFGEFGGQVQLTCDVVGEPTPQVKWFRNAESVDAHIESGRYTLNTDNTLVIKKL 423 Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVY-DPPSINLSPNSVNVESGNVARFTCTATGRPE 321 IL D + C A N G SAS +L V P + L P +V G A +C A G P Sbjct: 424 ILDDAAMFQCLAINEAGENSASTWLRVKTSAPIMELPPQNVTALDGKDATISCRAVGSPN 483 Query: 322 PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381 P + W N T + SR + + +L N ++ +C N AGS Sbjct: 484 PNITWIY--NETQLVDISSR-----VQILESGDLLISN--IRSVDAGLYICVRANEAGSV 534 Query: 382 FVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE-PI-IAWYFEGEAL- 438 L+V I P + T+ + A C P P I WY EG++ Sbjct: 535 KGEAYLSVLVRTQ-----IIQPPVDTTVLLGLTATLQCKVSSDPSVPYNIDWYREGQSST 589 Query: 439 -IQNHRR-NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL-LVDSPINPNIHFF 495 I N +R V DG L ++ + SD G+Y CV +S G + L +++ P P+ Sbjct: 590 PISNSQRIGVQADGQLEIQAVRASDVGSYACVVTSPGGNETRAARLSVIELPFPPS---- 645 Query: 496 RAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPR 555 V LP P + I + S T + N+ I S + + EV E G P Sbjct: 646 -NVKVERLPEPQQRSI-----NVSWTPGFDGNSPI--SKFIIQRREVSELEKFVG-PVPD 696 Query: 556 NSRGWVVIARRV--HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNS 613 W+ V Q ++++L Y F V N G PS S+ V + ++ S Sbjct: 697 PLLNWITELSNVSADQRWILLENLKAATVYQFRVSAVNRVGEGSPSEPSNVVELPQEAPS 756 Query: 614 LWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDN 673 G S + I+T P++ +IL + LF Y +N Sbjct: 757 -GPPVGFVGSARSMSEIITQW------QPPLEEHR---NGQILGYILRYRLFGY----NN 802 Query: 674 ITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDG 733 + Y+ T + F I L + Y + + G + +T + VP+ Sbjct: 803 VPWSYQNIT---NEAQRNFLIQELITWKDYIVQIAAYNNMGVGVYTEGSKIKTKEGVPEA 859 Query: 734 PPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNV 769 PP N+++ +N+T +W+PP Q NGI GY + Sbjct: 860 PPTNVKVEAINSTAARCRWTPPNPQQINGINQGYKI 895 Score = 111 bits (267), Expect = 1e-22 Identities = 123/465 (26%), Positives = 183/465 (39%), Gaps = 46/465 (9%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 L C A G P P RW K GV V D S F R H DAG Y C A N Sbjct: 93 LQCHALGYPQPTYRWLKDGV-PVGDFSSS-------QFYR-FHSTRREDAGSYQCIARND 143 Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLECLPPRGSPEPNVYWKKNGQTL 149 G+ S + + VA + F E + + G + + P P P+V W+ L Sbjct: 144 AGSIFSEKSDVVVAYM-GIFENTTEGRLTVISGHPAIFDMPPIESIPVPSVMWQSEDGPL 202 Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK--------IHIK 201 + D + L+I A + D Y+ A N +E + A + I + Sbjct: 203 NY--DIKYAFTHANQLIILSADENDRKGYRAKAINTQLGKEESSAFVHLNVSGDPYIEVA 260 Query: 202 PYLITGPEDVVAQTGSSVT-FQCRVGGDPLPDV--LWRRSAGGGNMPLGRVKVLDD---G 255 P +I P+DV + G+ V QC PL ++ LW + G G L+D Sbjct: 261 PEIIVRPQDVKVKVGTGVVELQCIANARPLHELETLWLKD-GLAVETAGVRHTLNDPWNR 319 Query: 256 SLRLDNVILADEGEYSCEAENSVG---AVSASGYLTVYDPPSINLSPNSVNV--ESGNVA 310 +L L + GEY+C+ G AVSAS L + +PP + +P E G Sbjct: 320 TLALLQANSSHSGEYTCQVRLRSGGYPAVSASARLQILEPP-LFFTPMRAETFGEFGGQV 378 Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370 + TC G P P + W N + + +Y + L I +D+ Sbjct: 379 QLTCDVVGEPTPQVKWF--RNAESVDAHIESGRY----TLNTDNTLVIKKLILDDAA-MF 431 Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA 430 C A+N AG + L V + PI+ P N T A C A+ +P P I Sbjct: 432 QCLAINEAGENSASTWLRVKTS----APIMELPPQNVTALDGKDATISCRAVGSPNPNIT 487 Query: 431 WYFEGEALIQ-NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 W + L+ + R + G L++ ++ D+G Y CV ++ G Sbjct: 488 WIYNETQLVDISSRVQILESGDLLISNIRSVDAGLYICVRANEAG 532 Score = 98.3 bits (234), Expect = 1e-18 Identities = 88/317 (27%), Positives = 128/317 (40%), Gaps = 10/317 (3%) Query: 11 APYIIEQPLDVTVARHQPAT-LNCRAGGSPSPAIR--WYKGGVLVVSDTHRSILPAGGLF 67 AP II +P DV V L C A P + W K G+ V + R L Sbjct: 260 APEIIVRPQDVKVKVGTGVVELQCIANARPLHELETLWLKDGLAVETAGVRHTLNDPWNR 319 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ--GDTV 125 L S +G Y C+ G + +A+ + +L P ++ G V Sbjct: 320 TLALLQAN-SSHSGEYTCQVRLRSGGYPAVSASARLQILEPPLFFTPMRAETFGEFGGQV 378 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARN 184 L C G P P V W +N +++ +S + ++ N LVI+ DA +QC+A N Sbjct: 379 QLTC-DVVGEPTPQVKWFRNAESVDAHIESGRYTLNTDNTLVIKKLILDDAAMFQCLAIN 437 Query: 185 AAGTRESAIATLKIHIK-PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 AG SA L++ P + P++V A G T CR G P P++ W + Sbjct: 438 EAG-ENSASTWLRVKTSAPIMELPPQNVTALDGKDATISCRAVGSPNPNITWIYNETQLV 496 Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303 RV++L+ G L + N+ D G Y C N G+V YL+V I P Sbjct: 497 DISSRVQILESGDLLISNIRSVDAGLYICVRANEAGSVKGEAYLSVLVRTQIIQPPVDTT 556 Query: 304 VESGNVARFTCTATGRP 320 V G A C + P Sbjct: 557 VLLGLTATLQCKVSSDP 573 Score = 65.3 bits (152), Expect = 1e-08 Identities = 89/387 (22%), Positives = 151/387 (39%), Gaps = 40/387 (10%) Query: 110 FRLEPESKQS--AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVI 167 F P S S ++G T +L+C G P+P W K+G + S+ + Sbjct: 74 FTTHPSSSGSIVSEGSTKILQC-HALGYPQPTYRWLKDGVPVGDFSSSQFYR-------F 125 Query: 168 QDARQTDAGRYQCIARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQC-RV 225 R+ DAG YQCIARN AG+ S + + + ++ + T + +G F + Sbjct: 126 HSTRREDAGSYQCIARNDAGSIFSEKSDVVVAYMGIFENTTEGRLTVISGHPAIFDMPPI 185 Query: 226 GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENS-VGAVSAS 284 P+P V+W+ G N + + L + + D Y +A N+ +G +S Sbjct: 186 ESIPVPSVMWQSEDGPLNYDI-KYAFTHANQLIILSADENDRKGYRAKAINTQLGKEESS 244 Query: 285 GYLTVY---DP-----PSINLSPNSVNVESG-NVARFTCTATGRP--EPTMFWSVEG--N 331 ++ + DP P I + P V V+ G V C A RP E W +G Sbjct: 245 AFVHLNVSGDPYIEVAPEIIVRPQDVKVKVGTGVVELQCIANARPLHELETLWLKDGLAV 304 Query: 332 RTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTS 391 T D ++ T + +L N + + + + Y S +L + Sbjct: 305 ETAGVRHTLNDPWNRT-----LALLQANSSHSGEYTCQVRLRSGGYPAVS-ASARLQIL- 357 Query: 392 DDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL---IQNHRRNVTN 448 PP T + C + P P + W+ E++ I++ R + Sbjct: 358 ---EPPLFFTPMRAETFGEFGGQVQLTCDVVGEPTPQVKWFRNAESVDAHIESGRYTLNT 414 Query: 449 DGTLVLKDLDKSDSGTYTCVASSRHGK 475 D TLV+K L D+ + C+A + G+ Sbjct: 415 DNTLVIKKLILDDAAMFQCLAINEAGE 441 Score = 60.5 bits (140), Expect = 3e-07 Identities = 47/200 (23%), Positives = 85/200 (42%), Gaps = 13/200 (6%) Query: 639 IEATPIDSKTIKLMWEILNFYYLEG------LFIYFRPLDNI--TIEYEMKTILHSNDVS 690 ++ PI + ++++ W L G I ++ L + ++ KT +H + + Sbjct: 1579 LKVVPITTTSVRVQWSALETALWNGDASTGGYRILYQQLSDFPTALQSTPKTDVHGINEN 1638 Query: 691 GFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHL 750 ++ L++ YE ++PF + G + + VP G P ++ +++T V L Sbjct: 1639 SVVLSDLQQDRNYEIVVLPFNSQGPGPATPPAAVYVGEAVPTGEPRAVDAAPISSTEVRL 1698 Query: 751 KWSPPELQLQNGIITGYNV--VVNWLD---VPANKSMVAINTTVHQATSLIMTNLTSGVS 805 W PP+ +QNG I GY + +V + P K I ATS + L Sbjct: 1699 LWKPPKQSMQNGDILGYKIYYLVTYSPQALEPGRKWEEEIEVVSATATSHSLVFLDKFTE 1758 Query: 806 YSVQIAAETIIGLGPFSQKV 825 Y +Q+ A G GP S + Sbjct: 1759 YRIQLLAFNPAGDGPRSAPI 1778 Score = 54.0 bits (124), Expect = 2e-05 Identities = 37/123 (30%), Positives = 59/123 (47%), Gaps = 6/123 (4%) Query: 697 LRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPE 756 L K+T+Y ++ F +G S+ T+DDVPD + ++ +V + W+PP Sbjct: 935 LEKFTEYNISVLCFTDPGDGVASSQVAVMTMDDVPD-EVTGLHFDDVSDRSVKVLWAPP- 992 Query: 757 LQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETII 816 + NGI+TGY V D P ++ + N T T L + L + Y +I A T + Sbjct: 993 -RASNGILTGYTVRYQVKDRP--DTLKSFNLTADD-TELTVNQLQATTHYWFEIVAWTRV 1048 Query: 817 GLG 819 G G Sbjct: 1049 GSG 1051 Score = 54.0 bits (124), Expect = 2e-05 Identities = 41/151 (27%), Positives = 75/151 (49%), Gaps = 7/151 (4%) Query: 675 TIEYEMKTI-LHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDG 733 TI+Y +++ + + + + SL ++T YE + K S++ V +T + VP Sbjct: 1215 TIKYVPRSVVIEDHTANSHVLDSLEEWTLYEVKMNACNDVGCSKESDTAVERTREAVPSY 1274 Query: 734 PPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTV-HQA 792 P++++ ++TTV ++W Q +NG I GY V A++ ++ T+ + A Sbjct: 1275 GPLDVQANATSSTTVVVQWGEVPRQHRNGQIDGYKVFY----AAADRGQQVLHKTIPNNA 1330 Query: 793 T-SLIMTNLTSGVSYSVQIAAETIIGLGPFS 822 T + +T L V Y VQ+ A T +G G S Sbjct: 1331 TFTTTLTELKKYVVYHVQVLAYTRLGNGALS 1361 Score = 50.8 bits (116), Expect = 2e-04 Identities = 43/191 (22%), Positives = 82/191 (42%), Gaps = 14/191 (7%) Query: 639 IEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITI---------EYEMKTILHSNDV 689 ++A PI S ++L+W+ G + ++ +T ++E + + S Sbjct: 1686 VDAAPISSTEVRLLWKPPKQSMQNGDILGYKIYYLVTYSPQALEPGRKWEEEIEVVSATA 1745 Query: 690 SGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVH 749 + + L K+T+Y L+ F +G S +TL VP P+++ + ++ Sbjct: 1746 TSHSLVFLDKFTEYRIQLLAFNPAGDGPRSAPITVKTLPGVPSA-PLHLRFSDITMQSLE 1804 Query: 750 LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQ 809 + W PP + NG I GY +V + N+ T+L + NL V+Y+ Sbjct: 1805 VTWDPP--KFLNGEILGY--LVTYETTEENEKFSKQVKQKVSNTTLRVQNLEEEVTYTFT 1860 Query: 810 IAAETIIGLGP 820 + A+T + GP Sbjct: 1861 VRAQTSVDYGP 1871 Score = 50.0 bits (114), Expect = 4e-04 Identities = 35/131 (26%), Positives = 61/131 (46%), Gaps = 2/131 (1%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSN-SRVAQTLDDVPDGPPINIEMFILNTTTVHLKW 752 + +L+ T Y+F + + EG PS S V + + P GPP+ + + + +W Sbjct: 717 LENLKAATVYQFRVSAVNRVGEGSPSEPSNVVELPQEAPSGPPVGFVGSARSMSEIITQW 776 Query: 753 SPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAA 812 PP + +NG I GY ++ L N N T + ++ L + Y VQIAA Sbjct: 777 QPPLEEHRNGQILGY-ILRYRLFGYNNVPWSYQNITNEAQRNFLIQELITWKDYIVQIAA 835 Query: 813 ETIIGLGPFSQ 823 +G+G +++ Sbjct: 836 YNNMGVGVYTE 846 Score = 41.5 bits (93), Expect = 0.14 Identities = 32/138 (23%), Positives = 57/138 (41%), Gaps = 4/138 (2%) Query: 684 LHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNS-RVAQTLDDVPDGPPINIEMFI 742 ++ D +T L +T+Y L KPS + + QT+ P PP N+ + Sbjct: 1118 INDPDAETLTVTGLVPFTQYRLRLSASNVVGSSKPSEATKDFQTIQARPKHPPFNVTVRA 1177 Query: 743 LNTTTVHLKWSPPELQLQNGIITGYNVVVNWL-DVPANKSMVAINTTV--HQATSLIMTN 799 ++ + ++W P + G GYN+ L P V + + H A S ++ + Sbjct: 1178 MSAQQLRVRWIPLQQTEWYGNPRGYNISYKQLVKTPGTIKYVPRSVVIEDHTANSHVLDS 1237 Query: 800 LTSGVSYSVQIAAETIIG 817 L Y V++ A +G Sbjct: 1238 LEEWTLYEVKMNACNDVG 1255 Score = 41.1 bits (92), Expect = 0.18 Identities = 34/97 (35%), Positives = 45/97 (46%), Gaps = 8/97 (8%) Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPA--IRWYKGG--VLVVSDTHRSILPAGGLFFL 69 II+ P+D TV ATL C+ PS I WY+ G +S++ R + A G + Sbjct: 548 IIQPPVDTTVLLGLTATLQCKVSSDPSVPYNIDWYREGQSSTPISNSQRIGVQADGQLEI 607 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVL 106 +A SD G Y C T S G +R A L V L Sbjct: 608 QAVRA---SDVGSYACVVT-SPGGNETRAARLSVIEL 640 Score = 37.1 bits (82), Expect = 2.9 Identities = 33/139 (23%), Positives = 59/139 (42%), Gaps = 9/139 (6%) Query: 689 VSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINI---EMFILNT 745 +S F LR Y Y+F + G + SR + + +P P + + ++ + T Sbjct: 1529 LSSFTAVGLRPYMTYQFRIQATNDL--GPSAFSRESVIVRTLPAAPAVGVGGLKVVPITT 1586 Query: 746 TTVHLKWSPPELQLQNGIIT--GYNVVVNWLDVPANKSMVAINTTVH--QATSLIMTNLT 801 T+V ++WS E L NG + GY ++ L T VH S+++++L Sbjct: 1587 TSVRVQWSALETALWNGDASTGGYRILYQQLSDFPTALQSTPKTDVHGINENSVVLSDLQ 1646 Query: 802 SGVSYSVQIAAETIIGLGP 820 +Y + + G GP Sbjct: 1647 QDRNYEIVVLPFNSQGPGP 1665 Score = 36.3 bits (80), Expect = 5.1 Identities = 43/199 (21%), Positives = 79/199 (39%), Gaps = 13/199 (6%) Query: 639 IEATPIDSKTIKLMW-EILNFY---YLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEI 694 ++A S T+ + W E+ + ++G +++ D + KTI +N + Sbjct: 1279 VQANATSSTTVVVQWGEVPRQHRNGQIDGYKVFYAAADRGQ-QVLHKTI-PNNATFTTTL 1336 Query: 695 TSLRKYTKYEFFLIPFYKKFEGKPSNSRV-AQTLDDVPDGPPINIEMFILNTTTVHLKWS 753 T L+KY Y ++ + + G S + QT +D P G P N+ ++ T + W Sbjct: 1337 TELKKYVVYHVQVLAYTRLGNGALSTPPIRVQTFEDTP-GVPSNVSFPDVSLTMARIIWD 1395 Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAE 813 P NG I Y V + + + + T L G YS A+ Sbjct: 1396 VP--VDPNGKILAYQVTYT---LNGSAMLNYSREFPPSDRTFRATELLPGKYYSFSCTAQ 1450 Query: 814 TIIGLGPFSQKVYFNIDSR 832 T +G G + + + ++R Sbjct: 1451 TRLGWGKIATALVYTTNNR 1469 >UniRef50_UPI0000E47478 Cluster: PREDICTED: similar to hemicentin, partial; n=6; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to hemicentin, partial - Strongylocentrotus purpuratus Length = 1839 Score = 138 bits (333), Expect = 1e-30 Identities = 135/480 (28%), Positives = 196/480 (40%), Gaps = 42/480 (8%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTH-RSILPAGGLFFLR 70 P I+EQP VT + P TL CRA G+P PA W K G L D++ R+ L G L Sbjct: 515 PSIVEQPESVTGDQRIPLTLTCRAIGTPEPAYYWEKDGALFDMDSNDRASLDGGNLVIES 574 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC- 129 T +D G Y C A N V+ + P Q +QG + L C Sbjct: 575 LT----TADDGQYQCFANNR-------------LVMEQFENTAPAMVQLSQGQPLKLRCG 617 Query: 130 -LP--PRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA-RN 184 P P G+P P +YW + + ++R++ GNLV + +DA Y C+A N Sbjct: 618 GSPGIPNGNPAPLIYWTDASPKHTSITYNARINQDLEGNLVFSNIIASDAKGYYCLAINN 677 Query: 185 AAGT-RESAIATLKIHIKP------YLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 G + S L + P +L + P VA S +C G P P + W+ Sbjct: 678 VVGLFQRSPKIMLSVTDLPAVASAAHLDSHPAASEVANRTQSFKLKCIAFGYPTPVITWK 737 Query: 237 RSAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295 R GRV + + G +L + V +DEG Y+C A N+ G S +TV P Sbjct: 738 RGEEQLQSG-GRVSIEESGQALVISAVENSDEGTYTCVASNTGGDDEFSTVVTVESAPYF 796 Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF-PGMSRDKYHATAVFDGVT 354 P+ G C + G P PT+ W V G F + +++ + Sbjct: 797 LAPPSDKTKGPGESVDIECRSEGVPPPTVEWLVNGQTWADFESNIDTERWTVVTGDPQLA 856 Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--K 412 + I + DS N C A N L V S P I + P + L + Sbjct: 857 TIAITNLQTTDS-NVFQCIATNKYKEELTSVVLNVVS---FPARITSFTPLTRRLSVVED 912 Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT-NDGTLVLKDLDKSDSGTYTCVASS 471 A F C + P+P I W F+G L + + +G+LV+ ++ K D G Y C A + Sbjct: 913 DSAKFICHSRGRPDPTITWTFKGSVLTNGIKYTINETEGSLVINNVKKVDGGEYECRAEN 972 Score = 133 bits (322), Expect = 2e-29 Identities = 135/502 (26%), Positives = 205/502 (40%), Gaps = 46/502 (9%) Query: 4 DYVTSGEAPYIIEQPLDVTVA-RHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62 D A ++ P VA R Q L C A G P+P I W +G + S SI Sbjct: 694 DLPAVASAAHLDSHPAASEVANRTQSFKLKCIAFGYPTPVITWKRGEEQLQSGGRVSIEE 753 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122 +G + A +SD G Y C A+N+ G +T+ F P K G Sbjct: 754 SGQALVISAVE---NSDEGTYTCVASNTGGD--DEFSTVVTVESAPYFLAPPSDKTKGPG 808 Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLL-FDGD---SRMHLVDG----GNLVIQDARQTD 174 ++V +EC G P P V W NGQT F+ + R +V G + I + + TD Sbjct: 809 ESVDIECRS-EGVPPPTVEWLVNGQTWADFESNIDTERWTVVTGDPQLATIAITNLQTTD 867 Query: 175 AGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTG----SSVTFQCRVGGDPL 230 + +QCIA N E L + P IT + + S F C G P Sbjct: 868 SNVFQCIATNKY-KEELTSVVLNVVSFPARITSFTPLTRRLSVVEDDSAKFICHSRGRPD 926 Query: 231 PDVLWRRSAGGGNMPLGRVKVLDD--GSLRLDNVILADEGEYSCEAENSVGA----VSAS 284 P + W + G + G +++ GSL ++NV D GEY C AEN++ + S Sbjct: 927 PTITW--TFKGSVLTNGIKYTINETEGSLVINNVKKVDGGEYECRAENAIDGEDYEATGS 984 Query: 285 GYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP---EPTMFWSVEGNRTIIFPGMSR 341 LT+ +I LSP ++ + GN A F C T EP ++W +G R + Sbjct: 985 ATLTMLGKTTIYLSPANLMIREGNTATFQCEITYDEELIEPYVYWMKDGQR------LEA 1038 Query: 342 DKYHATAVFDGVTVL-TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR----- 395 +++ + + L + + +S + + A+ AG + + + D R Sbjct: 1039 NQFLDSGGVRFMRCLPPLATSASRESISRSIVEAIQAAGPEGLLPEGRTRAHDTRRYIGY 1098 Query: 396 --PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTL 452 PP I P + + C A TPEP W +G + ++ R + G L Sbjct: 1099 NDVPPSIVEQPESINGDQRVPLTLTCRATGTPEPTYYWEKDGALFNVDSNDRVSLDGGNL 1158 Query: 453 VLKDLDKSDSGTYTCVASSRHG 474 V+K L +D G Y C A +R G Sbjct: 1159 VIKSLTTADDGQYQCFAKNRLG 1180 Score = 105 bits (251), Expect = 1e-20 Identities = 129/462 (27%), Positives = 187/462 (40%), Gaps = 48/462 (10%) Query: 38 SPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97 SP+P I W +G + S SI + A +SD G Y C A+NS G Sbjct: 1290 SPTPVITWKRGEEQLQSGGRVSIHEHE--LVISAVE---NSDEGTYTCVASNSGGD--DE 1342 Query: 98 NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL-FDGD-- 154 +T+ F P + G++V +EC G P P V W NGQ F+ + Sbjct: 1343 FSTVVTVESAPYFPYPPSDESKRPGESVDIEC-RSEGVPAPTVDWFVNGQPWADFESNRD 1401 Query: 155 -SRMHLVDG----GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK---PYLIT 206 R +V G + I + + TD+ +QCIA N +++ I P Sbjct: 1402 TERWEVVTGDPQLATISITNLQTTDSNVFQCIATNMYKEELTSVVLNVFSIPASIPSFTP 1461 Query: 207 GPEDVVAQTGSSVTFQCRVGG-----------DPLPDVLWRRSAGGGNMPLGRVKVLDDG 255 + S F C V G DP P + W+R GRV + + G Sbjct: 1462 LTRKLSVVQNDSAKFTCHVEGRPLPIIKISVLDPTPVITWKRGEEQLQSG-GRVSIQEFG 1520 Query: 256 -SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV-YD-PPSINLSPNSVNVESGNVARF 312 L + ++DEG Y+C A N+ G S +TV YD PPSI P S+N + Sbjct: 1521 QELVIFAFEISDEGTYTCVASNTGGDDEFSTVVTVEYDVPPSIVEQPESINGDERIPLTL 1580 Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372 TC ATG PEPT +W +G +F S D+ DG ++ + T +D + C Sbjct: 1581 TCRATGTPEPTYYWEKDG---ALFNVDSNDR----VSLDGGNLVIESLTTADDGQ--YQC 1631 Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPI-ITNGPSNQTLPIK-SMAVFPCTAICTPEPIIA 430 A N G++ + LT + D+ I +Q P+K P TP P+I Sbjct: 1632 FAKNRLGTAMSQKILTSLAFMDQFENIEPARIQVSQGQPLKLRCGGSPGVPNGTPAPLIY 1691 Query: 431 WYF---EGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469 W + + N R N G LV ++ SD+ Y C A Sbjct: 1692 WTDATPKPTPITYNARINQDPQGNLVFSNVIASDAKGYYCQA 1733 Score = 105 bits (251), Expect = 1e-20 Identities = 105/414 (25%), Positives = 172/414 (41%), Gaps = 41/414 (9%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-----DTHRSI 60 VT APY P D + + + CR+ G P+P + W+ G DT R Sbjct: 1347 VTVESAPYFPYPPSDESKRPGESVDIECRSEGVPAPTVDWFVNGQPWADFESNRDTERWE 1406 Query: 61 LPAGG--LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEF-RLEPESK 117 + G L + T+ + +D+ V+ C ATN Y + + L+V + P ++ Sbjct: 1407 VVTGDPQLATISITNLQT-TDSNVFQCIATNMYKEELT-SVVLNVFSIPASIPSFTPLTR 1464 Query: 118 QSA--QGDTVVLEC------LPPRG----SPEPNVYWKKNGQTLLFDGDSRMHLVD-GGN 164 + + Q D+ C LP P P + WK+ + L G R+ + + G Sbjct: 1465 KLSVVQNDSAKFTCHVEGRPLPIIKISVLDPTPVITWKRGEEQLQSGG--RVSIQEFGQE 1522 Query: 165 LVIQDARQTDAGRYQCIARNAAGTRE-SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223 LVI +D G Y C+A N G E S + T++ + P ++ PE + +T C Sbjct: 1523 LVIFAFEISDEGTYTCVASNTGGDDEFSTVVTVEYDVPPSIVEQPESINGDERIPLTLTC 1582 Query: 224 RVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSA 283 R G P P W + N+ LD G+L ++++ AD+G+Y C A+N +G + Sbjct: 1583 RATGTPEPTYYWEKDGALFNVDSNDRVSLDGGNLVIESLTTADDGQYQCFAKNRLGTAMS 1642 Query: 284 SGYLT--VYDPPSINLSPNSVNVESGNVARFTC-----TATGRPEPTMFWSVEGNRTIIF 336 LT + N+ P + V G + C G P P ++W T Sbjct: 1643 QKILTSLAFMDQFENIEPARIQVSQGQPLKLRCGGSPGVPNGTPAPLIYW------TDAT 1696 Query: 337 PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV-NYAGSSFVRGKLTV 389 P + Y+A D L ++ +D++ C A+ N GSS K+T+ Sbjct: 1697 PKPTPITYNARINQDPQGNLVFSNVIASDAKG-YYCQAINNVVGSSQRSPKVTL 1749 Score = 104 bits (250), Expect = 1e-20 Identities = 136/503 (27%), Positives = 200/503 (39%), Gaps = 64/503 (12%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I+EQP + + P TL CRA G+P P W K G L D++ + GG +++ Sbjct: 1103 PSIVEQPESINGDQRVPLTLTCRATGTPEPTYYWEKDGALFNVDSNDRVSLDGGNLVIKS 1162 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC-- 129 +D G Y C A N GTA S+ +A + + EP Q +G + L C Sbjct: 1163 L---TTADDGQYQCFAKNRLGTAMSQKILTSLAFMDQFENTEPAWIQVRRGRPLKLLCGG 1219 Query: 130 LP--PRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA-RNA 185 P P G+P P +YW + ++R+ GNLV A +DA Y C A N Sbjct: 1220 SPGIPNGNPAPLIYWTNAAAKPTPITYNARIAQDPEGNLVFSHAIASDAQGYYCQAINNI 1279 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 G+ + P I P V+ T Q + GG R S + Sbjct: 1280 VGSSQRT---------P--IISPTPVI--TWKRGEEQLQSGG--------RVSIHEHELV 1318 Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP-NSVNV 304 + V+ D+G+ + E+S +V V ++ Y Y P + P SV++ Sbjct: 1319 ISAVENSDEGTYTCVASNSGGDDEFS-----TVVTVESAPYFP-YPPSDESKRPGESVDI 1372 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD-K 363 E C + G P PT+ W V G F +RD V + TI+ T+ + Sbjct: 1373 E--------CRSEGVPAPTVDWFVNGQPWADFES-NRDTERWEVVTGDPQLATISITNLQ 1423 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPC-- 419 N C A N L V S P I + P + L + A F C Sbjct: 1424 TTDSNVFQCIATNMYKEELTSVVLNVFS---IPASIPSFTPLTRKLSVVQNDSAKFTCHV 1480 Query: 420 ---------TAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVA 469 ++ P P+I W E L R ++ G LV+ + SD GTYTCVA Sbjct: 1481 EGRPLPIIKISVLDPTPVITWKRGEEQLQSGGRVSIQEFGQELVIFAFEISDEGTYTCVA 1540 Query: 470 SSRHGKYVWSGALLVDSPINPNI 492 S+ G +S + V+ + P+I Sbjct: 1541 SNTGGDDEFSTVVTVEYDVPPSI 1563 Score = 99.5 bits (237), Expect = 5e-19 Identities = 95/357 (26%), Positives = 145/357 (40%), Gaps = 25/357 (7%) Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194 SP P + WK+ + L G +H + LVI +D G Y C+A N+ G E + Sbjct: 1290 SPTPVITWKRGEEQLQSGGRVSIHEHE---LVISAVENSDEGTYTCVASNSGGDDEFS-T 1345 Query: 195 TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-----GNMPLGRV 249 + + PY P D + G SV +CR G P P V W + N R Sbjct: 1346 VVTVESAPYFPYPPSDESKRPGESVDIECRSEGVPAPTVDWFVNGQPWADFESNRDTERW 1405 Query: 250 KVLDD----GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSI-NLSP--NS 301 +V+ ++ + N+ D + C A N S L V+ P SI + +P Sbjct: 1406 EVVTGDPQLATISITNLQTTDSNVFQCIATNMYKEELTSVVLNVFSIPASIPSFTPLTRK 1465 Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHA---TAVFDGVTVLTI 358 ++V + A+FTC GRP P + SV +I ++ + ++ + L I Sbjct: 1466 LSVVQNDSAKFTCHVEGRPLPIIKISVLDPTPVITWKRGEEQLQSGGRVSIQEFGQELVI 1525 Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418 + +D T C A N G +TV D PP I P + + Sbjct: 1526 FAFEISDE-GTYTCVASNTGGDDEFSTVVTVEYD---VPPSIVEQPESINGDERIPLTLT 1581 Query: 419 CTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 C A TPEP W +G + ++ R + G LV++ L +D G Y C A +R G Sbjct: 1582 CRATGTPEPTYYWEKDGALFNVDSNDRVSLDGGNLVIESLTTADDGQYQCFAKNRLG 1638 Score = 94.7 bits (225), Expect = 1e-17 Identities = 90/329 (27%), Positives = 129/329 (39%), Gaps = 34/329 (10%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLR 70 P I+EQP + + P TL CRA G P P W K G L V R+ L G L Sbjct: 32 PSIVEQPESINGDQRIPLTLTCRATGIPEPTYYWEKDGSLFDVDSNDRASLDGGNLVIES 91 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC- 129 T +D G Y C A N + N E+ Q QG + L C Sbjct: 92 LT----TADDGQYQCFANNRLVMDQFENTAW-------------ETIQVDQGRPLKLRCG 134 Query: 130 -LP--PRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN- 184 P P G+P P +YW + ++R+ G+LV + +DA Y C A N Sbjct: 135 GSPGVPNGNPAPLMYWTDAAAKPTPISYNARISQDPEGSLVFSNVIASDAKGYYCQAINN 194 Query: 185 -AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVT-------FQCRVGGDPLPDVLWR 236 +++S TL + P + +G V S + +C G P P++ W+ Sbjct: 195 VVGSSQQSPKVTLMVSDLPAVDSGASLVTKPAASEIAIRTQSFKLKCIAYGYPTPEITWK 254 Query: 237 RSAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295 R GR+ + + G L + V +D+G Y+C A N G S +TV P Sbjct: 255 RGEEQLQSG-GRISIEESGQELVISTVENSDKGTYTCVASNCEGIDEFSTVVTVESAPYF 313 Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTM 324 P+ G C + G P PT+ Sbjct: 314 PAPPSDETKRPGESVDIECRSKGVPAPTL 342 Score = 92.7 bits (220), Expect = 6e-17 Identities = 110/451 (24%), Positives = 178/451 (39%), Gaps = 56/451 (12%) Query: 113 EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ 172 +PES Q + L C G+PEP YW+K+G D + R L DGGNLVI+ Sbjct: 520 QPESVTGDQRIPLTLTCRAI-GTPEPAYYWEKDGALFDMDSNDRASL-DGGNLVIESLTT 577 Query: 173 TDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR-----VGG 227 D G+YQC A N ++ ++ + T P V G + +C G Sbjct: 578 ADDGQYQCFANN------------RLVMEQFENTAPAMVQLSQGQPLKLRCGGSPGIPNG 625 Query: 228 DPLPDVLWRRSAGGGNMPLGRVKVLDD--GSLRLDNVILADEGEYSCEAENSVGAV---S 282 +P P + W ++ ++ D G+L N+I +D Y C A N+V + S Sbjct: 626 NPAPLIYWTDASPKHTSITYNARINQDLEGNLVFSNIIASDAKGYYCLAINNVVGLFQRS 685 Query: 283 ASGYLTVYDPPSI----NLSPNSVNVESGNVA---RFTCTATGRPEPTMFWSVEGNRTII 335 L+V D P++ +L + E N + C A G P P + W G + Sbjct: 686 PKIMLSVTDLPAVASAAHLDSHPAASEVANRTQSFKLKCIAFGYPTPVITWK-RGEEQLQ 744 Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395 G ++ + L I+ + +D T C A N G +TV S Sbjct: 745 SGGR-------VSIEESGQALVISAVENSDE-GTYTCVASNTGGDDEFSTVVTVES---- 792 Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG------EALIQNHRRNV-TN 448 P PS++T C + P P + W G E+ I R V T Sbjct: 793 -APYFLAPPSDKTKGPGESVDIECRSEGVPPPTVEWLVNGQTWADFESNIDTERWTVVTG 851 Query: 449 D---GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL-LVDSPINPNIHFFRAADVSSLP 504 D T+ + +L +DS + C+A++++ + + S L +V P +S + Sbjct: 852 DPQLATIAITNLQTTDSNVFQCIATNKYKEELTSVVLNVVSFPARITSFTPLTRRLSVVE 911 Query: 505 GPPTKPITHNVTDTSVTLSWSQNNKIGSSSI 535 K I H+ T++W+ + ++ I Sbjct: 912 DDSAKFICHSRGRPDPTITWTFKGSVLTNGI 942 Score = 88.2 bits (209), Expect = 1e-15 Identities = 60/196 (30%), Positives = 90/196 (45%), Gaps = 10/196 (5%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I+EQP + P TL CRA G+P P W K G L D++ + GG + + Sbjct: 1561 PSIVEQPESINGDERIPLTLTCRATGTPEPTYYWEKDGALFNVDSNDRVSLDGGNLVIES 1620 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC-- 129 +D G Y C A N GTA S+ +A + + +EP Q +QG + L C Sbjct: 1621 L---TTADDGQYQCFAKNRLGTAMSQKILTSLAFMDQFENIEPARIQVSQGQPLKLRCGG 1677 Query: 130 LP--PRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN-- 184 P P G+P P +YW + ++R++ GNLV + +DA Y C A N Sbjct: 1678 SPGVPNGTPAPLIYWTDATPKPTPITYNARINQDPQGNLVFSNVIASDAKGYYCQAINNV 1737 Query: 185 AAGTRESAIATLKIHI 200 ++ S TL++ + Sbjct: 1738 VGSSQRSPKVTLRVRV 1753 Score = 87.0 bits (206), Expect = 3e-15 Identities = 102/379 (26%), Positives = 153/379 (40%), Gaps = 59/379 (15%) Query: 113 EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ 172 +PES Q + L C G PEP YW+K+G D + R L DGGNLVI+ Sbjct: 37 QPESINGDQRIPLTLTCRAT-GIPEPTYYWEKDGSLFDVDSNDRASL-DGGNLVIESLTT 94 Query: 173 TDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR-----VGG 227 D G+YQC A N ++ + + T E + G + +C G Sbjct: 95 ADDGQYQCFANN------------RLVMDQFENTAWETIQVDQGRPLKLRCGGSPGVPNG 142 Query: 228 DPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEA-ENSVGAVSA 283 +P P + W A P+ R+ +GSL NVI +D Y C+A N VG+ Sbjct: 143 NPAPLMYW-TDAAAKPTPISYNARISQDPEGSLVFSNVIASDAKGYYCQAINNVVGSSQQ 201 Query: 284 SGYLT--VYDPPSINLSPNSVNVESGN-VA------RFTCTATGRPEPTMFWSVEGNRTI 334 S +T V D P+++ + V + + +A + C A G P P + W G + Sbjct: 202 SPKVTLMVSDLPAVDSGASLVTKPAASEIAIRTQSFKLKCIAYGYPTPEITWK-RGEEQL 260 Query: 335 IFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394 G ++ + L I+ T +N + T C A N G +TV S Sbjct: 261 QSGG-------RISIEESGQELVIS-TVENSDKGTYTCVASNCEGIDEFSTVVTVESAPY 312 Query: 395 RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN--DGTL 452 P P PS++T C + P P + N + N +G+L Sbjct: 313 FPAP-----PSDETKRPGESVDIECRSKGVPAPTLT----------NRDKYTVNETEGSL 357 Query: 453 VLKDLDKSDSGTYTCVASS 471 V+ ++ K DSG Y C A + Sbjct: 358 VINNVKKVDSGEYECRAEN 376 Score = 85.8 bits (203), Expect = 6e-15 Identities = 79/305 (25%), Positives = 130/305 (42%), Gaps = 32/305 (10%) Query: 195 TLKIH-IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD 253 T+ IH + P ++ PE + +T CR G P P W + ++ LD Sbjct: 24 TVPIHDVPPSIVEQPESINGDQRIPLTLTCRATGIPEPTYYWEKDGSLFDVDSNDRASLD 83 Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313 G+L ++++ AD+G+Y C A N + V D N + ++ V+ G + Sbjct: 84 GGNLVIESLTTADDGQYQCFANNRL----------VMDQFE-NTAWETIQVDQGRPLKLR 132 Query: 314 CTAT-----GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368 C + G P P M+W+ + Y+A D L ++ +D++ Sbjct: 133 CGGSPGVPNGNPAPLMYWTDAAAKPTPI------SYNARISQDPEGSLVFSNVIASDAKG 186 Query: 369 TIVCSAVN-YAGSSFVRGKLTVTSDD----DRPPPIITNGPSNQTLPIKSMAV-FPCTAI 422 C A+N GSS K+T+ D D ++T P+ + I++ + C A Sbjct: 187 -YYCQAINNVVGSSQQSPKVTLMVSDLPAVDSGASLVTK-PAASEIAIRTQSFKLKCIAY 244 Query: 423 CTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481 P P I W E L R ++ G LV+ ++ SD GTYTCVAS+ G +S Sbjct: 245 GYPTPEITWKRGEEQLQSGGRISIEESGQELVISTVENSDKGTYTCVASNCEGIDEFSTV 304 Query: 482 LLVDS 486 + V+S Sbjct: 305 VTVES 309 Score = 83.8 bits (198), Expect = 3e-14 Identities = 76/275 (27%), Positives = 118/275 (42%), Gaps = 34/275 (12%) Query: 21 VTVARHQPATLNCRAG-----GSPSPAIRWYKGGVLVVSDTHRSIL---PAGGLFFLRAT 72 + V + +P L C G+P+P + W ++ + + P G L F Sbjct: 121 IQVDQGRPLKLRCGGSPGVPNGNPAPLMYWTDAAAKPTPISYNARISQDPEGSLVFSNV- 179 Query: 73 HGRVHSDAGVYWCEATNSY--GTARSRNATLHVAVLRE-----EFRLEPESKQSA-QGDT 124 + SDA Y+C+A N+ + +S TL V+ L +P + + A + + Sbjct: 180 ---IASDAKGYYCQAINNVVGSSQQSPKVTLMVSDLPAVDSGASLVTKPAASEIAIRTQS 236 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIAR 183 L+C+ G P P + WK+ + L G R+ + + G LVI +D G Y C+A Sbjct: 237 FKLKCIA-YGYPTPEITWKRGEEQLQSGG--RISIEESGQELVISTVENSDKGTYTCVAS 293 Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 N G E + + + PY P D + G SV +CR G P P L R N Sbjct: 294 NCEGIDEFS-TVVTVESAPYFPAPPSDETKRPGESVDIECRSKGVPAP-TLTNRDKYTVN 351 Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSV 278 +GSL ++NV D GEY C AEN++ Sbjct: 352 ET--------EGSLVINNVKKVDSGEYECRAENAI 378 Score = 83.8 bits (198), Expect = 3e-14 Identities = 76/303 (25%), Positives = 124/303 (40%), Gaps = 29/303 (9%) Query: 195 TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254 TL P ++ PE V +T CR G P P W + +M LD Sbjct: 508 TLLDDFPPSIVEQPESVTGDQRIPLTLTCRAIGTPEPAYYWEKDGALFDMDSNDRASLDG 567 Query: 255 GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314 G+L ++++ AD+G+Y C A N + + ++ N +P V + G + C Sbjct: 568 GNLVIESLTTADDGQYQCFANNRL-------VMEQFE----NTAPAMVQLSQGQPLKLRC 616 Query: 315 TAT-----GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369 + G P P ++W T P + Y+A D L ++ +D++ Sbjct: 617 GGSPGIPNGNPAPLIYW------TDASPKHTSITYNARINQDLEGNLVFSNIIASDAKG- 669 Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPI----ITNGPSNQTLPIKSMAV-FPCTAICT 424 C A+N F R + S D P + + P+ + ++ + C A Sbjct: 670 YYCLAINNVVGLFQRSPKIMLSVTDLPAVASAAHLDSHPAASEVANRTQSFKLKCIAFGY 729 Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483 P P+I W E L R ++ G LV+ ++ SD GTYTCVAS+ G +S + Sbjct: 730 PTPVITWKRGEEQLQSGGRVSIEESGQALVISAVENSDEGTYTCVASNTGGDDEFSTVVT 789 Query: 484 VDS 486 V+S Sbjct: 790 VES 792 Score = 77.8 bits (183), Expect = 2e-12 Identities = 82/337 (24%), Positives = 126/337 (37%), Gaps = 38/337 (11%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 ++V A C + G P P I W +KG VL + G L D Sbjct: 907 LSVVEDDSAKFICHSRGRPDPTITWTFKGSVLTNGIKYTINETEGSLVINNVKK----VD 962 Query: 80 AGVYWCEATNSY-GTARSRNATLHVAVL-REEFRLEPESKQSAQGDTVVLECLPPRGSP- 136 G Y C A N+ G + + +L + L P + +G+T +C Sbjct: 963 GGEYECRAENAIDGEDYEATGSATLTMLGKTTIYLSPANLMIREGNTATFQCEITYDEEL 1022 Query: 137 -EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ-------DARQTDAGRYQCIARNAAGT 188 EP VYW K+GQ L ++ L GG ++ A + R A AAG Sbjct: 1023 IEPYVYWMKDGQRL----EANQFLDSGGVRFMRCLPPLATSASRESISRSIVEAIQAAGP 1078 Query: 189 -------RESAIATLKI----HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 R A T + + P ++ PE + +T CR G P P W + Sbjct: 1079 EGLLPEGRTRAHDTRRYIGYNDVPPSIVEQPESINGDQRVPLTLTCRATGTPEPTYYWEK 1138 Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT--VYDPPSI 295 N+ LD G+L + ++ AD+G+Y C A+N +G + LT + Sbjct: 1139 DGALFNVDSNDRVSLDGGNLVIKSLTTADDGQYQCFAKNRLGTAMSQKILTSLAFMDQFE 1198 Query: 296 NLSPNSVNVESGNVARFTCTAT-----GRPEPTMFWS 327 N P + V G + C + G P P ++W+ Sbjct: 1199 NTEPAWIQVRRGRPLKLLCGGSPGIPNGNPAPLIYWT 1235 >UniRef50_Q8C310-3 Cluster: Isoform 3 of Q8C310 ; n=2; Murinae|Rep: Isoform 3 of Q8C310 - Mus musculus (Mouse) Length = 1057 Score = 138 bits (333), Expect = 1e-30 Identities = 82/209 (39%), Positives = 113/209 (54%), Gaps = 18/209 (8%) Query: 5 YVTSGEA----PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSDTH 57 ++ GEA P I+ P D + PA + CR+ G P P IRW G + D H Sbjct: 21 FIMGGEALDSPPQILVHPQDQLLQGSGPAKMRCRSSGQPPPTIRWLLNGQPLSMATPDLH 80 Query: 58 RSILPAGGLFFLR-ATHGRVHSDA-------GVYWCEATNSYGTARSRNATLHVAVLREE 109 +LP G L R + GR D GVY CEA+N GTA SR A L VAVL+E+ Sbjct: 81 Y-LLPDGTLLLHRPSVQGRPQDDQNILSAILGVYTCEASNRLGTAVSRGARLSVAVLQED 139 Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169 F+++P + G+++VLEC PP G P+P+V W K+G+ L+ R V G +L++ Sbjct: 140 FQIQPRDTVAVVGESLVLECGPPWGYPKPSVSWWKDGKPLVLQPGRR--TVSGDSLMVSR 197 Query: 170 ARQTDAGRYQCIARNAAGTRESAIATLKI 198 A + D+G Y C+A N AG RES A + I Sbjct: 198 AEKNDSGTYMCMATNNAGQRESRAARVSI 226 Score = 60.5 bits (140), Expect = 3e-07 Identities = 48/192 (25%), Positives = 90/192 (46%), Gaps = 14/192 (7%) Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR-TIIFPGMSRDKYHATAVF 350 PP I + P ++ A+ C ++G+P PT+ W + G ++ P + T + Sbjct: 31 PPQILVHPQDQLLQGSGPAKMRCRSSGQPPPTIRWLLNGQPLSMATPDLHYLLPDGTLLL 90 Query: 351 DGVTVLTINDTDKNDSRNTI---VCSAVNYAGSSFVRG---KLTVTSDDDRPPPIITNGP 404 +V D+N + C A N G++ RG + V +D + P T Sbjct: 91 HRPSVQGRPQDDQNILSAILGVYTCEASNRLGTAVSRGARLSVAVLQEDFQIQPRDTVAV 150 Query: 405 SNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI-QNHRRNVTNDGTLVLKDLDKSDSG 463 ++L ++ + P+P ++W+ +G+ L+ Q RR V+ D +V + +K+DSG Sbjct: 151 VGESLVLECGPPWGY-----PKPSVSWWKDGKPLVLQPGRRTVSGDSLMVSR-AEKNDSG 204 Query: 464 TYTCVASSRHGK 475 TY C+A++ G+ Sbjct: 205 TYMCMATNNAGQ 216 Score = 57.2 bits (132), Expect = 3e-06 Identities = 43/124 (34%), Positives = 59/124 (47%), Gaps = 8/124 (6%) Query: 703 YEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNG 762 YEF + P + G SN + + + VP PP + + N + V + W+PP + NG Sbjct: 320 YEFKVRPSSGRARGPDSNVLLLRLPEQVPSAPPQGVTLRSGNGS-VFVSWAPPPAESHNG 378 Query: 763 IITGYNVVVNWLDVPANKSMVAIN-TTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPF 821 +I GY V W N S+ A N T V + T L + G SY VQ+AA T G G Sbjct: 379 VIRGYQV---W--SLGNASLPAANWTVVGEQTQLEIATRLPG-SYCVQVAAVTGAGAGEL 432 Query: 822 SQKV 825 S V Sbjct: 433 STPV 436 Score = 54.8 bits (126), Expect = 1e-05 Identities = 53/194 (27%), Positives = 80/194 (41%), Gaps = 26/194 (13%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK-VLDDGSLRL- 259 P ++ P+D + Q +CR G P P + W + +M + +L DG+L L Sbjct: 32 PQILVHPQDQLLQGSGPAKMRCRSSGQPPPTIRWLLNGQPLSMATPDLHYLLPDGTLLLH 91 Query: 260 -----------DNVILADEGEYSCEAENSVG-AVSASGYLTV-YDPPSINLSPNSVNVES 306 N++ A G Y+CEA N +G AVS L+V + P Sbjct: 92 RPSVQGRPQDDQNILSAILGVYTCEASNRLGTAVSRGARLSVAVLQEDFQIQPRDTVAVV 151 Query: 307 GNVARFTC-TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365 G C G P+P++ W +G ++ PG T D L ++ +KND Sbjct: 152 GESLVLECGPPWGYPKPSVSWWKDGKPLVLQPG------RRTVSGDS---LMVSRAEKND 202 Query: 366 SRNTIVCSAVNYAG 379 S T +C A N AG Sbjct: 203 S-GTYMCMATNNAG 215 Score = 35.5 bits (78), Expect = 8.9 Identities = 32/104 (30%), Positives = 44/104 (42%), Gaps = 15/104 (14%) Query: 394 DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN--HRRNVTNDGT 451 D PP I+ + P +Q L A C + P P I W G+ L + DGT Sbjct: 29 DSPPQILVH-PQDQLLQGSGPAKMRCRSSGQPPPTIRWLLNGQPLSMATPDLHYLLPDGT 87 Query: 452 LVL------------KDLDKSDSGTYTCVASSRHGKYVWSGALL 483 L+L +++ + G YTC AS+R G V GA L Sbjct: 88 LLLHRPSVQGRPQDDQNILSAILGVYTCEASNRLGTAVSRGARL 131 >UniRef50_UPI0000F33D9D Cluster: Perlecan; n=1; Bos taurus|Rep: Perlecan - Bos Taurus Length = 3005 Score = 137 bits (331), Expect = 2e-30 Identities = 147/525 (28%), Positives = 209/525 (39%), Gaps = 67/525 (12%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVS-DTHRSILPAGGL 66 G AP I + VA Q L C G + W++ GG L TH S L Sbjct: 1879 GGAPPIRIETSSSHVAEGQTLDLKCVVPGQAHAQVTWHRRGGSLPARHQTHGSRL----- 1933 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126 H SD+G Y C G+ + + T+ V + ++P S QG Sbjct: 1934 ----RLHHVSQSDSGEYVCRVVGGSGSEQEASFTITVRLRSPVISIDPPSSTVQQGQDAS 1989 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNA 185 +CL G+ ++ WK Q L + + + G+++ I AR ++ G Y+C+A NA Sbjct: 1990 FKCLVHDGAAPISLEWKTRNQEL----EDNVRISPNGSIITIVGARPSNHGAYRCVASNA 2045 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 G +S + L +H PY T PE + G +V QC G P W R GG++P Sbjct: 2046 YGVAQS-VVNLSVHGPPYATTVPEHASVRAGEAVQLQCLAHGTPPLTFQWSRV--GGHLP 2102 Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAEN--------SVGAV---------SASGYLT 288 G + L + D G Y C+ N SV V AS +L Sbjct: 2103 AG--ATARNELLLFEAAAPEDSGRYRCQVTNRHREGLQSSVAHVLLLLKASGQPASPHLL 2160 Query: 289 VYDP--PS--INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344 P PS IN+ + +V G+ F C A G P+P + WS G R + PG+ + Sbjct: 2161 PSSPALPSVLINIRTSVQSVVVGHAVEFECLALGDPKPQVTWSKVGGR--LRPGIVQSG- 2217 Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404 V + + D R C+A N AG++ L V + P I T P Sbjct: 2218 ------GIVRIARVELADAGQYR----CTATNAAGTTQSHVLLLVQA----LPQIST--P 2261 Query: 405 SNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGT 464 +P S AVFPC P P I W L + R + L+L + D+GT Sbjct: 2262 PEVRVPAGSTAVFPCMVSGYPAPEITWSKLDGNLPPDSR---LENHMLLLPSVQPQDAGT 2318 Query: 465 YTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTK 509 Y C A++R GK L V + P +F S LP P K Sbjct: 2319 YVCTATNRQGKVKAFAQLQVPERVVP---YFTQTPYSFLPLPTIK 2360 Score = 109 bits (261), Expect = 6e-22 Identities = 135/513 (26%), Positives = 200/513 (38%), Gaps = 54/513 (10%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWY--KGGVL-VVSDTHRSILPAGGLF 67 AP + P +TV Q A C A G P P++ W GG L + HR IL Sbjct: 1402 APVVSIHPPQLTVQPGQMAEFRCSATGHPMPSLEWTGGPGGQLPQKAQVHRGILR----- 1456 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV-AVLREEFRLEPESKQSAQGDTVV 126 L A SD G Y C A +S G +R A LHV ++ PE Q +G TV Sbjct: 1457 -LPAVEA---SDQGQYLCRAHSSAGQHVAR-AVLHVHGGNGPRVQVSPERTQVHEGRTVR 1511 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186 L C G P + W+K G +L +R D L+I DAG Y C+A + A Sbjct: 1512 LYC-RAAGVPSATITWRKEGGSL--PPQARAERTDIATLLIPAITAADAGFYLCVATSPA 1568 Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQT-----GSSVTFQCRVGGDPLPDVLWRRSAGG 241 GT A A +++ + P T P + + + G ++ C V G + W + GG Sbjct: 1569 GT---AQARIQVVVLPGATTPPVRIESSSPSVTEGQTLDLNCVVAGLAHSQITWYK-RGG 1624 Query: 242 GNMPLGRVKVLDDGSLR-LDNVILADEGEYSCEAENSVGAVSASGYLTV--YDPPSINLS 298 P +V+ GSL + AD GEY C EN G AS ++V P + + Sbjct: 1625 SLPPHAQVR----GSLSPVVGAPRADSGEYVCRVENDSGPKEASIIVSVPPGPVPPVRIE 1680 Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358 +S V G C G+ + W G P + V G + Sbjct: 1681 SSSPTVAEGQTLDLNCVVAGQAHAPVTWYKRGG---TLPARHQ-------VPGGRKIFQA 1730 Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-F 417 + D + VC A N +S +TVT +T +N+ + + Sbjct: 1731 SPADAGE----YVCRASNGVEASIT---VTVTKTQGANFAYLTPKNNNKAKVAEGQTLDL 1783 Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477 C P + W+ G +L H+ + ++ L + + +DSG Y C S+ G Sbjct: 1784 NCLVSGQPHAQVTWHKRGGSLPARHQLHSESE-LLRIPQVTPADSGEYVCHVSNGAGSQE 1842 Query: 478 WSGALLVDSPINPNIHFFRAADVSSLPGPPTKP 510 S L+V + + H A+ + P T P Sbjct: 1843 TS--LIVTIQGSDSSHAGAGAEGARSPSSLTSP 1873 Score = 97.9 bits (233), Expect = 1e-18 Identities = 121/486 (24%), Positives = 181/486 (37%), Gaps = 46/486 (9%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64 +V G P + P V + L CRA G PS I W K G + Sbjct: 1486 HVHGGNGPRVQVSPERTQVHEGRTVRLYCRAAGVPSATITWRKEGGSLPPQARAERTDIA 1545 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGD 123 L T +DAG Y C AT+ GTA++R + R+E S +G Sbjct: 1546 TLLIPAIT----AADAGFYLCVATSPAGTAQARIQVVVLPGATTPPVRIESSSPSVTEGQ 1601 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183 T+ L C+ G + W K G +L R G + A + D+G Y C Sbjct: 1602 TLDLNCV-VAGLAHSQITWYKRGGSLPPHAQVR-----GSLSPVVGAPRADSGEYVCRVE 1655 Query: 184 NAAGTRESAI--ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241 N +G +E++I + + P I VA+ G ++ C V G V W + G Sbjct: 1656 NDSGPKEASIIVSVPPGPVPPVRIESSSPTVAE-GQTLDLNCVVAGQAHAPVTWYKR--G 1712 Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN---LS 298 G +P R +V G ++ AD GEY C A N V AS +TV N L+ Sbjct: 1713 GTLP-ARHQV--PGGRKIFQASPADAGEYVCRASN---GVEASITVTVTKTQGANFAYLT 1766 Query: 299 P---NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY-----HATAVF 350 P N V G C +G+P + W G + + T Sbjct: 1767 PKNNNKAKVAEGQTLDLNCLVSGQPHAQVTWHKRGGSLPARHQLHSESELLRIPQVTPAD 1826 Query: 351 DGVTVLTINDTDKNDSRNTIVC-----SAVNYAGSSFVRGKLTVTSD----DDRPPPIIT 401 G V +++ + + IV S+ AG+ R ++TS PPI Sbjct: 1827 SGEYVCHVSNGAGSQETSLIVTIQGSDSSHAGAGAEGARSPSSLTSPCGPAPGGAPPIRI 1886 Query: 402 NGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSD 461 S+ +++ + C + W+ G +L H+ T+ L L + +SD Sbjct: 1887 ETSSSHVAEGQTLDL-KCVVPGQAHAQVTWHRRGGSLPARHQ---THGSRLRLHHVSQSD 1942 Query: 462 SGTYTC 467 SG Y C Sbjct: 1943 SGEYVC 1948 Score = 93.9 bits (223), Expect = 2e-17 Identities = 101/393 (25%), Positives = 147/393 (37%), Gaps = 40/393 (10%) Query: 111 RLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA 170 ++ P QG L C GSP YW + L + H G L Sbjct: 1308 QVHPTRSVVPQGGPHSLRC-QVSGSPPHYFYWSREDGRPLPSSTQQRH--QGSELHFPSV 1364 Query: 171 RQTDAGRYQCIARN---AAGTRESAIAT----LKIHIKPYLITGPEDVVAQTGSSVTFQC 223 + +DAG Y C RN A +R + T P + P + Q G F+C Sbjct: 1365 QPSDAGVYICTCRNLHHANTSRAELLVTDPSPSATPSAPVVSIHPPQLTVQPGQMAEFRC 1424 Query: 224 RVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSA 283 G P+P + W GG L + + G LRL V +D+G+Y C A +S G A Sbjct: 1425 SATGHPMPSLEWTGGPGG---QLPQKAQVHRGILRLPAVEASDQGQYLCRAHSSAGQHVA 1481 Query: 284 SGYLTVY--DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341 L V+ + P + +SP V G R C A G P T+ W EG P +R Sbjct: 1482 RAVLHVHGGNGPRVQVSPERTQVHEGRTVRLYCRAAGVPSATITWRKEGGS---LPPQAR 1538 Query: 342 DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP-PII 400 A + L I D+ +C A + AG++ R ++ V PP I Sbjct: 1539 ------AERTDIATLLIPAITAADA-GFYLCVATSPAGTAQARIQVVVLPGATTPPVRIE 1591 Query: 401 TNGPS---NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL 457 ++ PS QTL + C I WY G +L + + + Sbjct: 1592 SSSPSVTEGQTLDLN------CVVAGLAHSQITWYKRGGSLPPHAQ---VRGSLSPVVGA 1642 Query: 458 DKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490 ++DSG Y C + G +++V P P Sbjct: 1643 PRADSGEYVCRVENDSGPK--EASIIVSVPPGP 1673 Score = 81.0 bits (191), Expect = 2e-13 Identities = 80/333 (24%), Positives = 120/333 (36%), Gaps = 23/333 (6%) Query: 10 EAPYIIE-QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68 +AP +++ P V + P +L C+ GSP W + + + + L F Sbjct: 1302 QAPLVVQVHPTRSVVPQGGPHSLRCQVSGSPPHYFYWSREDGRPLPSSTQQRHQGSELHF 1361 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATL------HVAVLREEFRLEPESKQSAQG 122 SDAGVY C N + SR L + P G Sbjct: 1362 PSVQP----SDAGVYICTCRNLHHANTSRAELLVTDPSPSATPSAPVVSIHPPQLTVQPG 1417 Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182 C G P P++ W G +++H G L + +D G+Y C A Sbjct: 1418 QMAEFRC-SATGHPMPSLEW-TGGPGGQLPQKAQVH---RGILRLPAVEASDQGQYLCRA 1472 Query: 183 RNAAGTRESAIATLKIH--IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 ++AG + A A L +H P + PE G +V CR G P + WR+ G Sbjct: 1473 HSSAG-QHVARAVLHVHGGNGPRVQVSPERTQVHEGRTVRLYCRAAGVPSATITWRKE-G 1530 Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---DPPSINL 297 G P R + D +L + + AD G Y C A + G A + V P + + Sbjct: 1531 GSLPPQARAERTDIATLLIPAITAADAGFYLCVATSPAGTAQARIQVVVLPGATTPPVRI 1590 Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330 +S +V G C G + W G Sbjct: 1591 ESSSPSVTEGQTLDLNCVVAGLAHSQITWYKRG 1623 Score = 52.8 bits (121), Expect = 5e-05 Identities = 50/204 (24%), Positives = 81/204 (39%), Gaps = 15/204 (7%) Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 P + + P V G C +G P +WS E R + P ++ ++ + Sbjct: 1304 PLVVQVHPTRSVVPQGGPHSLRCQVSGSPPHYFYWSREDGRPL--PSSTQQRHQGSE--- 1358 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT--SDDDRPP-PIITNGPSNQT 408 L +D+ +C+ N ++ R +L VT S P P+++ P T Sbjct: 1359 ----LHFPSVQPSDA-GVYICTCRNLHHANTSRAELLVTDPSPSATPSAPVVSIHPPQLT 1413 Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468 + MA F C+A P P + W G Q ++ + G L L ++ SD G Y C Sbjct: 1414 VQPGQMAEFRCSATGHPMPSLEW--TGGPGGQLPQKAQVHRGILRLPAVEASDQGQYLCR 1471 Query: 469 ASSRHGKYVWSGALLVDSPINPNI 492 A S G++V L V P + Sbjct: 1472 AHSSAGQHVARAVLHVHGGNGPRV 1495 Score = 51.6 bits (118), Expect = 1e-04 Identities = 32/85 (37%), Positives = 50/85 (58%), Gaps = 7/85 (8%) Query: 202 PYLITGPEDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDG---S 256 P ++T P++++ A G +VTF C G P P + WR + G++P RV V +G + Sbjct: 122 PQVVTPPQELIQASRGQTVTFTCVAIGVPTPIINWRLN--WGHIPSHPRVTVTSEGGRGT 179 Query: 257 LRLDNVILADEGEYSCEAENSVGAV 281 L + +V AD+G Y+CEA N+ G V Sbjct: 180 LTIHDVKEADQGAYTCEAMNARGMV 204 Score = 48.4 bits (110), Expect = 0.001 Identities = 35/116 (30%), Positives = 50/116 (43%), Gaps = 8/116 (6%) Query: 397 PPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TL 452 PP + P + V F C AI P PII W + + R VT++G TL Sbjct: 121 PPQVVTPPQELIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTL 180 Query: 453 VLKDLDKSDSGTYTCVASSRHGKY--VWSGA--LLVDSPINPNIHFFRAADVSSLP 504 + D+ ++D G YTC A + G + G L+ P+ HF+ S LP Sbjct: 181 TIHDVKEADQGAYTCEAMNARGMVFGIPDGVLELIPQRGPCPDGHFYLEHSASCLP 236 Score = 41.5 bits (93), Expect = 0.14 Identities = 25/82 (30%), Positives = 36/82 (43%), Gaps = 2/82 (2%) Query: 12 PYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 P ++ P + + +R Q T C A G P+P I W + S ++ GG L Sbjct: 122 PQVVTPPQELIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTL- 180 Query: 71 ATHGRVHSDAGVYWCEATNSYG 92 H +D G Y CEA N+ G Sbjct: 181 TIHDVKEADQGAYTCEAMNARG 202 Score = 38.3 bits (85), Expect = 1.3 Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 2/71 (2%) Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAG 176 Q+++G TV C+ G P P + W+ N + + G G L I D ++ D G Sbjct: 133 QASRGQTVTFTCVAI-GVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLTIHDVKEADQG 191 Query: 177 RYQCIARNAAG 187 Y C A NA G Sbjct: 192 AYTCEAMNARG 202 >UniRef50_Q4RVM0 Cluster: Chromosome 9 SCAF14991, whole genome shotgun sequence; n=8; Euteleostomi|Rep: Chromosome 9 SCAF14991, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 478 Score = 136 bits (330), Expect = 3e-30 Identities = 132/434 (30%), Positives = 181/434 (41%), Gaps = 38/434 (8%) Query: 32 NCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 +C A G P+P RW + R L G L R D GVY C A+NS Sbjct: 43 SCEAQGHPAPFYRWKLNDSFIHPRPGSRYSLMGGNLHISRLNKDE---DVGVYQCLASNS 99 Query: 91 YGTARSRNATLHVAVLREEFRLEPESK-QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149 +GT SR A+LHVA L E+F+ S + +G VVL C PP S E W N Sbjct: 100 FGTIVSREASLHVAYL-EDFKTHRRSPVRVREGQGVVLLCGPPPHSGELTFTWIFNEYPS 158 Query: 150 LFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGTRESAIA-----TLKI----- 198 D+R + GNL I +D G Y C+ N T+ S L++ Sbjct: 159 FVTQDTRRFVSQKTGNLYIAKVVPSDVGNYTCVVTNTV-TKSSVQGPPTPLVLRVDGVMG 217 Query: 199 HIKPYL-ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD--DG 255 +P + + PE V S+VT +C G+P+P + WRR+ G GR ++ G Sbjct: 218 EYEPKIEVQFPEVVPVAKSSTVTLECFALGNPVPTISWRRADGAS---FGRKVDVNKASG 274 Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315 L + + D G Y C AENS G S G L+ Y P ++ P V + C Sbjct: 275 VLEIPYFQIEDAGMYECVAENSRGRNSVKGKLSFYAAPQLSEKPQDVQKTIDETLVWECK 334 Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375 A+ +P+P+ W G D+ V +G VLTI+ + D C A Sbjct: 335 ASAKPKPSYRWLKNGEPL----DHMEDRLQ---VNNG--VLTISSLNLADI-GMYQCVAE 384 Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFE 434 N G F +L V + P N QTL + V C +P II+W Sbjct: 385 NRHGRVFTNAELRVIA---IAPDFSQNLLKAQTLTRQGGDVLIECKPRMSPRGIISWRKG 441 Query: 435 GEALIQNHRRNVTN 448 EAL +NHR + N Sbjct: 442 KEALRENHRPELQN 455 Score = 102 bits (244), Expect = 7e-20 Identities = 101/376 (26%), Positives = 147/376 (39%), Gaps = 33/376 (8%) Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA-RQTDAGRYQCIAR 183 VV C +G P P WK N + SR L+ GGNL I + D G YQC+A Sbjct: 40 VVFSC-EAQGHPAPFYRWKLNDSFIHPRPGSRYSLM-GGNLHISRLNKDEDVGVYQCLAS 97 Query: 184 NAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRV---GGDPLPDVLWRRSA 239 N+ GT S A+L + +++ + V + G V C G+ ++ Sbjct: 98 NSFGTIVSREASLHVAYLEDFKTHRRSPVRVREGQGVVLLCGPPPHSGELTFTWIFNEYP 157 Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV---------- 289 R G+L + V+ +D G Y+C N+V S G T Sbjct: 158 SFVTQDTRRFVSQKTGNLYIAKVVPSDVGNYTCVVTNTVTKSSVQGPPTPLVLRVDGVMG 217 Query: 290 -YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348 Y+P P V V + C A G P PT+ W + G D A+ Sbjct: 218 EYEPKIEVQFPEVVPVAKSSTVTLECFALGNPVPTISWRRADGASF---GRKVDVNKASG 274 Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408 V + + I D + C A N G + V+GKL+ + P ++ P + Sbjct: 275 VLE-IPYFQIEDAGMYE------CVAENSRGRNSVKGKLSFYA-----APQLSEKPQDVQ 322 Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468 I V+ C A P+P W GE L R N+G L + L+ +D G Y CV Sbjct: 323 KTIDETLVWECKASAKPKPSYRWLKNGEPLDHMEDRLQVNNGVLTISSLNLADIGMYQCV 382 Query: 469 ASSRHGKYVWSGALLV 484 A +RHG+ + L V Sbjct: 383 AENRHGRVFTNAELRV 398 Score = 71.3 bits (167), Expect = 1e-10 Identities = 62/225 (27%), Positives = 92/225 (40%), Gaps = 11/225 (4%) Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74 ++ P V VA+ TL C A G+P P I W + + A G+ L + Sbjct: 225 VQFPEVVPVAKSSTVTLECFALGNPVPTISWRRADGASFG-RKVDVNKASGV--LEIPYF 281 Query: 75 RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRG 134 ++ DAG+Y C A NS G + A + +P+ Q +T+V EC Sbjct: 282 QI-EDAGMYECVAENSRGRNSVKGKLSFYAA--PQLSEKPQDVQKTIDETLVWEC-KASA 337 Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194 P+P+ W KNG+ L D R+ V+ G L I D G YQC+A N G + Sbjct: 338 KPKPSYRWLKNGEPLDHMED-RLQ-VNNGVLTISSLNLADIGMYQCVAENRHGRVFTNAE 395 Query: 195 TLKIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 I I P + + G V +C+ P + WR+ Sbjct: 396 LRVIAIAPDFSQNLLKAQTLTRQGGDVLIECKPRMSPRGIISWRK 440 Score = 57.6 bits (133), Expect = 2e-06 Identities = 40/141 (28%), Positives = 63/141 (44%), Gaps = 8/141 (5%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 AP + E+P DV + C+A P P+ RW K G + + G+ + Sbjct: 311 APQLSEKPQDVQKTIDETLVWECKASAKPKPSYRWLKNGE-PLDHMEDRLQVNNGVLTIS 369 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEF--RLEPESKQSAQGDTVVLE 128 + + +D G+Y C A N +G + NA L V + +F L + QG V++E Sbjct: 370 SLN---LADIGMYQCVAENRHGRVFT-NAELRVIAIAPDFSQNLLKAQTLTRQGGDVLIE 425 Query: 129 CLPPRGSPEPNVYWKKNGQTL 149 C PR SP + W+K + L Sbjct: 426 C-KPRMSPRGIISWRKGKEAL 445 >UniRef50_A2AT18 Cluster: Titin; n=11; Eukaryota|Rep: Titin - Mus musculus (Mouse) Length = 8268 Score = 136 bits (329), Expect = 3e-30 Identities = 128/504 (25%), Positives = 195/504 (38%), Gaps = 25/504 (4%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 ++P+ +P+ + V + A C G+ + W K + + +I G L Sbjct: 2930 KSPFFDIKPVSIDVIAGESADFECHVTGAQPMRVTWSKDNKEIRPGGNYTITCVGNTPHL 2989 Query: 70 RATH-GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128 R G+ D+G Y C+ATN G +A L V + + SK + QG+++ LE Sbjct: 2990 RILKVGK--GDSGQYTCQATNDVGKDMC-SAQLSVKEPPKFIKKLDASKVAKQGESIQLE 3046 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAG 187 C GSPE V W +N L M V+ L I +A D G Y C A N G Sbjct: 3047 C-KISGSPEIKVVWFRNDSELHESWKYNMSFVNSVALLTINEASAEDTGDYICEAHNGVG 3105 Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW--RRSAGGGNMP 245 + A LK+ P P V A GS V QC + G P +V+W R + Sbjct: 3106 DASCSTA-LKVKAPPVFTQKPPPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRSSKK 3164 Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305 D SL + N+ D GEY C+A N VG+ + + + +PP + + Sbjct: 3165 FKITSKNFDTSLHIFNLEAPDIGEYHCKATNEVGSDTCACTVKFKEPPRFVKKLSDASTL 3224 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF-DGVTVLTINDTDKN 364 G+ G ++ W + I R+ + F D + L + + + Sbjct: 3225 IGDPVELQAVVEGFQPISVVWLKDKGEVI------RESENVRISFVDNIATLQLGSPEAS 3278 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424 S VC N AG LTV P I P T+ + C T Sbjct: 3279 QS-GKYVCQIKNDAGMRECSAVLTVLE-----PATIVEKPEPMTVTTGNPFTLECVVAGT 3332 Query: 425 PEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481 PE W+ +G L R ++T N +L + + +D G YT +R GK + + Sbjct: 3333 PELSAKWFKDGRELSSGSRHHITFVRNLASLKIPSAEMNDKGLYTFEVENRVGKSSCTVS 3392 Query: 482 LLVDSPINPNIHFFRAADVSSLPG 505 + V + P R D S+ G Sbjct: 3393 VHVSDRVVPPSFVRRLKDTSATLG 3416 Score = 136 bits (328), Expect = 5e-30 Identities = 137/527 (25%), Positives = 207/527 (39%), Gaps = 31/527 (5%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E PY IE V A +P TL C+ G+P I WYK + S + + L Sbjct: 3679 EPPYFIEPLEHVEAAIGEPITLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASL 3738 Query: 70 RATHGRVHSDAGVYWCEATNSYGT-ARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128 + HSD G Y C+A NS G A S + L F + + G V E Sbjct: 3739 -VINKVDHSDVGEYTCKAENSVGAVASSAVLVIKERKLPPSFARKLKDVHETLGFPVAFE 3797 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAG 187 C GS V W K+G+ L D + +M V L I Q+ G+Y C A N G Sbjct: 3798 CRI-NGSEPLQVSWYKDGELLKDDANLQMSFVHHVATLQILQTDQSHVGQYNCSASNPLG 3856 Query: 188 TRES-AIATLKIH-IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGG 241 T S A L H + P+ P V G S +F+C V G + W R G Sbjct: 3857 TASSSAKLILSEHEVPPFFDLKPVSVDLALGESGSFKCHVTGTAPIKITWAKDNREIRPG 3916 Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS-INLSPN 300 GN + V+ + +L + V D G+Y+C A N G S S L V +PP I Sbjct: 3917 GNYKMTLVE--NTATLTVLKVAKGDAGQYTCYASNVAGKDSCSAQLGVQEPPRFIKKLDQ 3974 Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360 S V+ R+ C G PE + W + + + D V +L ++ Sbjct: 3975 SRIVKQDEYTRYECKIGGSPEIKVLWYKDEVE------IQESSKFRMSFEDSVAILEMHS 4028 Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420 DS C A N AGS+ L V + PP+ P + C Sbjct: 4029 LSVEDS-GDYTCEARNAAGSASSSTSLKV-----KEPPVFRKKPFPVETLKGADVHLECE 4082 Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLV---LKDLDKSDSGTYTCVASSRHGKYV 477 TP ++W+ + L + + ++ L + ++D +D G Y C A++ G Sbjct: 4083 LQGTPPFQVSWHKDKRELRSGKKYKIMSENLLTSIHILNVDTADIGEYQCKATNDVGSDT 4142 Query: 478 WSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSW 524 G++ + +P P + D+S++ G + T ++++W Sbjct: 4143 CVGSVTMKAP--PQF-VKKLTDISTIIGKEVQLQTTIEGAEPISVAW 4186 Score = 133 bits (321), Expect = 3e-29 Identities = 134/521 (25%), Positives = 213/521 (40%), Gaps = 35/521 (6%) Query: 3 DDYVTSGEAPYIIEQ--PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI 60 D V++ E PY + + PL+ +V +L C+ G+P + W+KG + S Sbjct: 2731 DALVSTLEPPYFVTELEPLEASVG--DSVSLQCQVAGTPEITVSWFKGDTKLRSTPEYRT 2788 Query: 61 LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNA-TLHVAVLREEFRLEPESKQS 119 + L + +D+G Y C A NS GTA S+ + L F + + + Sbjct: 2789 YFTNNVATLVFNKVSI-NDSGEYTCMAENSIGTAASKTIFRIQERQLPPSFARQLKDIEQ 2847 Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRY 178 G V L C GS V W ++G L D + +M VD L I + +G+Y Sbjct: 2848 TVGLPVTLTC-RLNGSAPIQVCWYRDGVLLRDDENLQMSFVDNVATLKILQTDLSHSGQY 2906 Query: 179 QCIARNAAGTRESA--IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 C A N GT S + + P+ P + G S F+C V G V W Sbjct: 2907 SCSASNPLGTASSTARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRVTWS 2966 Query: 237 RS----AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292 + GGN + V + LR+ V D G+Y+C+A N VG S L+V +P Sbjct: 2967 KDNKEIRPGGNYTI--TCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEP 3024 Query: 293 PS-INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 P I S + G + C +G PE + W N + + KY+ + V + Sbjct: 3025 PKFIKKLDASKVAKQGESIQLECKISGSPEIKVVWF--RNDSELHESW---KYNMSFV-N 3078 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411 V +LTIN+ D+ +C A N G + L V + PP+ T P Sbjct: 3079 SVALLTINEASAEDT-GDYICEAHNGVGDASCSTALKV-----KAPPVFTQKPPPVGALK 3132 Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN---DGTLVLKDLDKSDSGTYTCV 468 S + C TP + W + + + + + +T+ D +L + +L+ D G Y C Sbjct: 3133 GSDVILQCEISGTPPFEVVWVKDRKQVRSSKKFKITSKNFDTSLHIFNLEAPDIGEYHCK 3192 Query: 469 ASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTK 509 A++ G + + P P + +D S+L G P + Sbjct: 3193 ATNEVGSDTCACTVKFKEP--PRF-VKKLSDASTLIGDPVE 3230 Score = 130 bits (314), Expect = 2e-28 Identities = 114/465 (24%), Positives = 192/465 (41%), Gaps = 27/465 (5%) Query: 33 CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG 92 C+ GGSP + WYK V + + + + L H D+G Y CEA N+ G Sbjct: 3988 CKIGGSPEIKVLWYKDEVEIQESSKFRMSFEDSVAILEM-HSLSVEDSGDYTCEARNAAG 4046 Query: 93 TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFD 152 +A S + +L V FR +P ++ +G V LEC +G+P V W K+ + L Sbjct: 4047 SASS-STSLKVKE-PPVFRKKPFPVETLKGADVHLEC-ELQGTPPFQVSWHKDKRELR-- 4101 Query: 153 GDSRMHLVDGGNLV----IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208 + + + NL+ I + D G YQC A N G+ ++ + ++ + P + Sbjct: 4102 -SGKKYKIMSENLLTSIHILNVDTADIGEYQCKATNDVGS-DTCVGSVTMKAPPQFVKKL 4159 Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL---DDGSLRLDNVILA 265 D+ G V Q + G V W + G + + + +L+ A Sbjct: 4160 TDISTIIGKEVQLQTTIEGAEPISVAWFKDKGEIVRESDNIWISYSENIATLQFSRAEPA 4219 Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325 + G+Y+C+ +N G L+V +P +I P S+ V +G+ CT +G PE + Sbjct: 4220 NAGKYTCQIKNDAGMQECYATLSVLEPAAIVEKPESIKVTTGDTCTLECTVSGTPELSTK 4279 Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385 W +G ++ D + + F+ V+ L I + DS N G Sbjct: 4280 WFKDGKE------LTSDNKYKISFFNKVSGLKIINVVPGDS-GVYSFEVQNPVGKDSC-- 4330 Query: 386 KLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN 445 K+++ D PP T S V C +P + W+ +G + + Sbjct: 4331 KVSIQVSDRIIPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVLWFHDGNEISSGRKYQ 4390 Query: 446 VT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 T N L + L+++D+G YTC+A++ G S L V P Sbjct: 4391 TTLTDNTCALTVNMLEEADAGDYTCIATNVAGSDECSAPLTVREP 4435 Score = 128 bits (310), Expect = 7e-28 Identities = 131/496 (26%), Positives = 206/496 (41%), Gaps = 25/496 (5%) Query: 2 SDDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL 61 S +T E P + P V V T G+P ++W+KG +VS +I Sbjct: 3485 SSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVSGEACTIS 3544 Query: 62 PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121 + L +G Y C TN G+A + T H+ V ++ + S + Sbjct: 3545 LEDFVTELELLEVEP-GQSGDYSCLVTNDAGSA---SCTTHLFVKEPATFVKRLADTSVE 3600 Query: 122 -GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQ 179 G +VLE G+P +V W KN L + + + +++ I ++ D +Y Sbjct: 3601 TGSPIVLEATYS-GTPPISVSWMKNEYPLSQSPNCGITTTEKSSILEILESTIEDYAQYA 3659 Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW-RRS 238 C+ N AG ++ A + + PY I E V A G +T QC+V G P + W + Sbjct: 3660 CLIENEAG-QDICEALVSVLEPPYFIEPLEHVEAAIGEPITLQCKVDGTPEIRISWYKEH 3718 Query: 239 AGGGNMPLGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPS 294 + P +++ ++ SL ++ V +D GEY+C+AENSVGAV++S L + + PPS Sbjct: 3719 TKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYTCKAENSVGAVASSAVLVIKERKLPPS 3778 Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354 V+ G F C G + W +G + D + V Sbjct: 3779 FARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGEL------LKDDANLQMSFVHHVA 3832 Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414 L I TD++ CSA N G++ KL ++ + PP P + L + Sbjct: 3833 TLQILQTDQSHV-GQYNCSASNPLGTASSSAKLILS--EHEVPPFFDLKPVSVDLALGES 3889 Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQ--NHRRN-VTNDGTLVLKDLDKSDSGTYTCVASS 471 F C T I W + + N++ V N TL + + K D+G YTC AS+ Sbjct: 3890 GSFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVAKGDAGQYTCYASN 3949 Query: 472 RHGKYVWSGALLVDSP 487 GK S L V P Sbjct: 3950 VAGKDSCSAQLGVQEP 3965 Score = 126 bits (304), Expect = 4e-27 Identities = 132/495 (26%), Positives = 216/495 (43%), Gaps = 33/495 (6%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAG 64 VT P +++ D++ + L G+ ++ W+K G +V + I + Sbjct: 4147 VTMKAPPQFVKKLTDISTIIGKEVQLQTTIEGAEPISVAWFKDKGEIVRESDNIWISYSE 4206 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGD 123 + L+ + ++AG Y C+ N G ATL +VL +E PES + GD Sbjct: 4207 NIATLQFSRAEP-ANAGKYTCQIKNDAGMQECY-ATL--SVLEPAAIVEKPESIKVTTGD 4262 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIA 182 T LEC G+PE + W K+G+ L D ++ + L I + D+G Y Sbjct: 4263 TCTLECTVS-GTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVVPGDSGVYSFEV 4321 Query: 183 RNAAGTRESAIATLKIH---IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239 +N G ++S ++++ I P ++ +GSSV +C+V G P VLW Sbjct: 4322 QNPVG-KDSCKVSIQVSDRIIPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVLWFHD- 4379 Query: 240 GGGNMPLGRV--KVLDDGSLRLDNVIL--ADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295 G + GR L D + L +L AD G+Y+C A N G+ S LTV +PPS Sbjct: 4380 -GNEISSGRKYQTTLTDNTCALTVNMLEEADAGDYTCIATNVAGSDECSAPLTVREPPSF 4438 Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355 P+ ++V +G+ FT G P T+ W +G+ T + PG + ++ D V Sbjct: 4439 VQKPDPMDVLTGSNVTFTSIVKGSPPFTVSW-FKGS-TELVPGARCN----VSLQDSVGE 4492 Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415 L + D D + S C N AG + +L V + P I ++ ++ Sbjct: 4493 LELFDVDTSQS-GEYTCIVSNEAGRASCTTRLFV-----KAPAIFVKRLNDYSIEKGKPL 4546 Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNV-TNDGTLVLKDLDKS--DSGTYTCVASSR 472 + T TP + W G +I + R N+ T + + +L+ L + DSG Y C + Sbjct: 4547 ILEGTFSGTPPISVTWKKNGINVIASQRCNITTTEKSAILEILSSTVEDSGQYNCYIENA 4606 Query: 473 HGKYVWSGALLVDSP 487 GK S +L+ P Sbjct: 4607 SGKDSCSAQILILEP 4621 Score = 121 bits (291), Expect = 1e-25 Identities = 123/507 (24%), Positives = 200/507 (39%), Gaps = 24/507 (4%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 + C+ GSP ++ W+ G + S L + +DAG Y C ATN Sbjct: 4362 MECKVYGSPPISVLWFHDGNEISSGRKYQTTLTDNTCAL-TVNMLEEADAGDYTCIATNV 4420 Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150 G+ +A L V F +P+ G V + +GSP V W K L+ Sbjct: 4421 AGSDEC-SAPLTVRE-PPSFVQKPDPMDVLTGSNVTFTSIV-KGSPPFTVSWFKGSTELV 4477 Query: 151 FDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209 + L D G L + D + +G Y CI N AG R S L + + Sbjct: 4478 PGARCNVSLQDSVGELELFDVDTSQSGEYTCIVSNEAG-RASCTTRLFVKAPAIFVKRLN 4536 Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD---DGSLRLDNVILAD 266 D + G + + G P V W+++ G + R + L + + + D Sbjct: 4537 DYSIEKGKPLILEGTFSGTPPISVTWKKN-GINVIASQRCNITTTEKSAILEILSSTVED 4595 Query: 267 EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326 G+Y+C EN+ G S S + + +PP V V G+ A C G PE + W Sbjct: 4596 SGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVTVGDSASLQCQLAGTPEIGVSW 4655 Query: 327 SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386 +G+ T + P + K H + V L D +DS +C A N G V Sbjct: 4656 -YKGD-TKLRP-TATCKMHFK---NNVATLVFTQVDSSDS-GEYICRAENSVGE--VSSS 4706 Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGEALIQNHRRN 445 +T + + PP + + + VF C A+ EPI ++WY +G+ L + Sbjct: 4707 TFLTVQEQKLPPSFSRQLRDVQETVGLPVVFEC-AVSGSEPISVSWYKDGKPLKDSPNIQ 4765 Query: 446 VT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSS 502 + N TL + D+S SG Y+C A++ G L++ NP A + + Sbjct: 4766 TSFLDNIATLNIFKTDRSLSGQYSCTATNPIGSASSGAKLILTEGKNPPFFDIPLAPMDA 4825 Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNK 529 + G H + ++W+++N+ Sbjct: 4826 VVGESADLECHVTGTQPIKVTWAKDNR 4852 Score = 120 bits (289), Expect = 2e-25 Identities = 124/529 (23%), Positives = 210/529 (39%), Gaps = 28/529 (5%) Query: 10 EAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68 +AP I + L D ++ + +P L G+P ++ W K G+ V++ +I Sbjct: 4526 KAPAIFVKRLNDYSIEKGKPLILEGTFSGTPPISVTWKKNGINVIASQRCNITTTEKSAI 4585 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVL 127 L V D+G Y C N+ G + + + +L + ++ E + GD+ L Sbjct: 4586 LEILSSTVE-DSGQYNCYIENASG---KDSCSAQILILEPPYFVKQLEPVKVTVGDSASL 4641 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAA 186 +C G+PE V W K L +MH + LV +D+G Y C A N+ Sbjct: 4642 QC-QLAGTPEIGVSWYKGDTKLRPTATCKMHFKNNVATLVFTQVDSSDSGEYICRAENSV 4700 Query: 187 GTRESA--IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GN 243 G S+ + + + P DV G V F+C V G V W + + Sbjct: 4701 GEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWYKDGKPLKD 4760 Query: 244 MPLGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLSP 299 P + LD+ +L + + G+YSC A N +G+ S+ L + + PP ++ Sbjct: 4761 SPNIQTSFLDNIATLNIFKTDRSLSGQYSCTATNPIGSASSGAKLILTEGKNPPFFDIPL 4820 Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359 ++ G A C TG + W+ + NR I G + Y + LTI Sbjct: 4821 APMDAVVGESADLECHVTGTQPIKVTWAKD-NREIRSGGNYQISY-----LENSAHLTIV 4874 Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419 DK DS C AVN G +L + + PP T S + + Sbjct: 4875 KVDKGDS-GQYTCYAVNEVGKDSCTAQLNIK--ERLIPPSFTKKLSETVEETEGNSFKLE 4931 Query: 420 TAICTPEPI-IAWYFEGEAL--IQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHGK 475 + +PI +AWY + N N+ L+ +K +D+G YTC A++ G Sbjct: 4932 GRVAGSQPITVAWYKNNVEIHPTSNCEIMFKNNALLLQVKRASMADAGLYTCKATNDAGS 4991 Query: 476 YVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSW 524 + + ++++ P P + A V++ G + H + + W Sbjct: 4992 ALCTSSIVIKEPKKPPVFDQHLAPVTASEGDSVQLSCHVQGSEPIRIQW 5040 Score = 120 bits (288), Expect = 3e-25 Identities = 120/475 (25%), Positives = 191/475 (40%), Gaps = 28/475 (5%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 AP I + + VA A C G+P+ +W+K G + SI + + L Sbjct: 116 APVIKRRIEPLEVALGHLAKFTCEIQGAPNVRFQWFKAGREIYESDKCSIRSSNYVSSLE 175 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA-VLREEFRLEPESKQSAQGDTVVLEC 129 +V D G Y C+A+N YG+ S ATL V F P++ + G C Sbjct: 176 ILRTQV-VDCGEYTCKASNEYGSV-SCTATLTVTEAYPPTFLSRPKALTTFVGKAAKFLC 233 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGT 188 G+P + W+K+G L D R+ D +L + + D G Y C A N G Sbjct: 234 -TVSGTPVIEIIWQKDGAALSPSPDCRVTDADNKHSLELSNLTVQDRGIYSCKASNKFGA 292 Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248 + A L I KP+ I E V + + +C+V D + W S G +P G+ Sbjct: 293 -DICQAELTIIDKPHFIKELEAVQSAINKKIHLECQVDEDRKVTITW--SKDGQKLPAGK 349 Query: 249 -VKV-LDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS-INLSPNSVN 303 K+ +D SL + L D G Y+C A N G+ S+S + V +PPS + S Sbjct: 350 DYKIYFEDKIASLEIPLAKLKDSGTYTCTASNEAGSSSSSAAVAVREPPSFVKKVDPSYL 409 Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363 + G AR C G P + W + N+ +S + + +L I D Sbjct: 410 MLPGESARLHCKLKGSPVIQVTW-FKNNKE-----LSESNTVRMSFVNSEAILDITDVKV 463 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423 +DS T C A N GS ++ + + PP + + A+ C Sbjct: 464 DDS-GTYSCEATNDVGSDSCSTEVVI-----KEPPSFIKTLEPADIVRGANALLQCEIAG 517 Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLV---LKDLDKSDSGTYTCVASSRHGK 475 T + W+ + + + + + + T V + + +D G Y CV ++ GK Sbjct: 518 TGPFEVNWFKDKKQIRSSKKYRLFTQKTFVYLEISSFNSADVGDYECVVANEVGK 572 Score = 119 bits (287), Expect = 4e-25 Identities = 119/477 (24%), Positives = 191/477 (40%), Gaps = 25/477 (5%) Query: 37 GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96 G+P I+W K V +VS I G FL + S G Y C+ TN G+ Sbjct: 2016 GTPPFKIKWLKDDVELVSGPKCFIGLEGSTSFLNL-YSVDSSKTGQYTCQVTNDVGSDSC 2074 Query: 97 RNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSR 156 L + +LE SK GD+ LEC GSPE V W +N L + Sbjct: 2075 TTMLLVTEPPKFVKKLEA-SKIIKAGDSARLEC-KITGSPEIQVVWYRNEHELTASDKYQ 2132 Query: 157 MHLVDGGNLVIQDARQT-DAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT 215 M +D ++ ++ T D+G + C A+N AG+ + + + P + P V Sbjct: 2133 MTFIDSVAVIQMNSLGTEDSGDFICEAQNPAGSTSCSTKVI-VKEPPVFSSFPPIVETLK 2191 Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSC 272 + V+ +C + G P +V+W + + KV S+ + NV D GEY C Sbjct: 2192 NTEVSLECELSGTPPFEVVWYKDKRQLRSSK-KYKVASKNFHASIHILNVESTDIGEYHC 2250 Query: 273 EAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332 +A+N VG+ + + + +PP NS+ V +G A + G ++ W E Sbjct: 2251 KAQNEVGSDACVCAVKLKEPPKFISKLNSLTVVAGEPAELQASIEGAQPISVQWLKEKEE 2310 Query: 333 TIIFPGMSRDKYHATAVF-DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTS 391 I R+ + F + V L + ++ +C N G LTV Sbjct: 2311 VI------RESENIRISFVNNVATLQFAKVEPANA-GKYICQVKNDGGVRENMATLTVLE 2363 Query: 392 DDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI--QNHRRNVTND 449 P +I + T+ + C TPE + WY +G+ L Q H+ + N Sbjct: 2364 -----PAVIIEKAGSMTVTVGETCALECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNK 2418 Query: 450 -GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPG 505 +L + ++K D+GTYT + GK + + V + P R D + G Sbjct: 2419 ISSLKILSVEKEDAGTYTFQVQNNVGKSSCTAVVDVSDRMVPPSFTRRLKDTGGVLG 2475 Score = 119 bits (286), Expect = 6e-25 Identities = 121/496 (24%), Positives = 193/496 (38%), Gaps = 27/496 (5%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64 ++T E PY +E+P V L GG+ I+W+K + RS+ Sbjct: 1422 HLTVKEPPYFVEKPQSQDVNPGTRVQLKALVGGTAPMTIKWFKDNKELHPGAARSVWKDD 1481 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124 L + +D+G Y C+ +N GT S+ AT+ V + + G + Sbjct: 1482 TSTILELFSAKA-ADSGTYICQLSNDVGTTSSK-ATIFVKEPPQFIKKPSPVLVLRNGQS 1539 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIAR 183 EC G+PE V W +G + + VDG I +AR ++G Y C AR Sbjct: 1540 TTFEC-QVTGTPEIRVSWYLDGNEITDLRKYGISFVDGLATFQISNARVENSGTYVCEAR 1598 Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 N AGT +I LK+ P I E V S V +C V G +V W ++ Sbjct: 1599 NDAGTASCSIE-LKVKEPPIFIRELEPVEVVKDSDVELECEVMGTTPFEVTWLKN--NKE 1655 Query: 244 MPLGRVKVLDDGS----LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299 + G+ + + L + +D GEY C N G+ + S + + +PPS Sbjct: 1656 IRSGKKYTMSEKMSVFYLHITKCDPSDVGEYQCIIANEGGSCACSARVALKEPPSFIKKI 1715 Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359 +V + A F T G P ++ W ++ ++ + D H + D V L + Sbjct: 1716 ENVTTVLKSSATFQSTVAGSPPISITW-LKDDQIL----EENDNVH-ISFEDSVATLQVR 1769 Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419 D N C A N +G L V P II S K C Sbjct: 1770 SVD-NGHSGRYTCQAKNESGIERCYAFLLV----QEPAQIIEKAKSVDVTE-KDPVTLEC 1823 Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKY 476 TPE + W +G+ ++ + +++ N + ++ + K DSG YT + G Sbjct: 1824 VVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSS 1883 Query: 477 VWSGAL-LVDSPINPN 491 L ++D I P+ Sbjct: 1884 SCDAYLRVLDQDIPPS 1899 Score = 118 bits (284), Expect = 1e-24 Identities = 117/489 (23%), Positives = 196/489 (40%), Gaps = 24/489 (4%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 VT P + +P +T + A C G+P I W K G + + A Sbjct: 206 VTEAYPPTFLSRPKALTTFVGKAAKFLCTVSGTPVIEIIWQKDGAALSPSPDCRVTDADN 265 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 L ++ V D G+Y C+A+N +G A A L + + + F E E+ QSA + Sbjct: 266 KHSLELSNLTVQ-DRGIYSCKASNKFG-ADICQAELTI-IDKPHFIKELEAVQSAINKKI 322 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARN 184 LEC + + W K+GQ L D +++ D +L I A+ D+G Y C A N Sbjct: 323 HLECQVDEDR-KVTITWSKDGQKLPAGKDYKIYFEDKIASLEIPLAKLKDSGTYTCTASN 381 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW-RRSAGGGN 243 AG+ S+ A ++ + G S C++ G P+ V W + + Sbjct: 382 EAGSSSSSAAVAVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSE 441 Query: 244 MPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302 R+ ++ + L + +V + D G YSCEA N VG+ S S + + +PPS + Sbjct: 442 SNTVRMSFVNSEAILDITDVKVDDSGTYSCEATNDVGSDSCSTEVVIKEPPSFIKTLEPA 501 Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362 ++ G A C G + W + + + + F + + + N D Sbjct: 502 DIVRGANALLQCEIAGTGPFEVNWFKDKKQ---IRSSKKYRLFTQKTFVYLEISSFNSAD 558 Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422 D +V + V G V + + PP + T + V A+ Sbjct: 559 VGD-YECVVANEVGKCG--------CVATHLLKEPPTFVKKVDDFT-ALAGQTVTLQAAV 608 Query: 423 CTPEPIIAWYFEGEALIQNH---RRNVTND-GTLVLKDLDKSDSGTYTCVASSRHGKYVW 478 EPI + +G+ +I+ + + +N L + D+ S G YTC+A + G Sbjct: 609 RGSEPISVMWMKGQEVIKEDGKIKMSFSNGVAVLTIPDVQISLGGKYTCLAENEAGSQTS 668 Query: 479 SGALLVDSP 487 G L+V P Sbjct: 669 VGELIVKEP 677 Score = 117 bits (281), Expect = 2e-24 Identities = 126/494 (25%), Positives = 197/494 (39%), Gaps = 39/494 (7%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P P V ++ +L C G+P + WYK + S + A F Sbjct: 2176 EPPVFSSFPPIVETLKNTEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKV--ASKNFHA 2233 Query: 70 RATHGRVHS-DAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVV 126 V S D G Y C+A N G+ +A + L+E +F + S G+ Sbjct: 2234 SIHILNVESTDIGEYHCKAQNEVGS----DACVCAVKLKEPPKFISKLNSLTVVAGEPAE 2289 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDS-RMHLVDG-GNLVIQDARQTDAGRYQCIARN 184 L+ G+ +V W K + ++ + ++ R+ V+ L +AG+Y C +N Sbjct: 2290 LQA-SIEGAQPISVQWLKEKEEVIRESENIRISFVNNVATLQFAKVEPANAGKYICQVKN 2348 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 G RE+ +ATL + +I + G + +C+V G P V W + G + Sbjct: 2349 DGGVREN-MATLTVLEPAVIIEKAGSMTVTVGETCALECKVAGTPELSVEWYKD---GKL 2404 Query: 245 PLGRVK-----VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSIN 296 K SL++ +V D G Y+ + +N+VG S + + V D PPS Sbjct: 2405 LTSSQKHKFSFYNKISSLKILSVEKEDAGTYTFQVQNNVGKSSCTAVVDVSDRMVPPSFT 2464 Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356 G C G ++ W E + + S KY T D V L Sbjct: 2465 RRLKDTGGVLGTSCILECKVAGSSPISIAWFHEKTKIV-----SGAKYQ-TTFSDNVCTL 2518 Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416 +N D +D + C A N AGS R LTV PP + + LP K++ Sbjct: 2519 QLNSLDSSD-MGSYTCVAANVAGSDECRALLTV----QEPPSFVKEPEPLEVLPGKNI-T 2572 Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRH 473 F TP + W+ L++ +R N+ + T L L ++D S SG YTCV S+ Sbjct: 2573 FTSVIRGTPPFKVGWFRGARELVKGNRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNA 2632 Query: 474 GKYVWSGALLVDSP 487 G+ + L V P Sbjct: 2633 GQASCTTRLFVKEP 2646 Score = 116 bits (280), Expect = 3e-24 Identities = 123/494 (24%), Positives = 205/494 (41%), Gaps = 29/494 (5%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 +T E P +++P + V + T G+P + W++G +V +I Sbjct: 2548 LTVQEPPSFVKEPEPLEVLPGKNITFTSVIRGTPPFKVGWFRGARELVKGNRCNIYFEDT 2607 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDT 124 + L + + S +G Y C +N+ G A + T + V ++ S S + G + Sbjct: 2608 VAELELFNIDI-SQSGEYTCVVSNNAGQA---SCTTRLFVKEPATFVKKLSDHSVEPGKS 2663 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCI 181 ++LE G+ +V WKK+G ++ R ++V L I + + DAG Y C Sbjct: 2664 IILEG-TYTGTLPISVTWKKDGVSI--TPSERCNIVTTEKTCILEILSSTKGDAGHYSCE 2720 Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW-RRSAG 240 N AG R++ A + PY +T E + A G SV+ QC+V G P V W + Sbjct: 2721 IENEAG-RDACDALVSTLEPPYFVTELEPLEASVGDSVSLQCQVAGTPEITVSWFKGDTK 2779 Query: 241 GGNMPLGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSIN 296 + P R ++ +L + V + D GEY+C AENS+G ++ + + PPS Sbjct: 2780 LRSTPEYRTYFTNNVATLVFNKVSINDSGEYTCMAENSIGTAASKTIFRIQERQLPPSFA 2839 Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356 + G TC G + W +G ++ + D+ + D V L Sbjct: 2840 RQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDG---VL---LRDDENLQMSFVDNVATL 2893 Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416 I TD + S CSA N G++ +L T+ + + P P + + A Sbjct: 2894 KILQTDLSHS-GQYSCSASNPLGTASSTARL--TAREPKKSPFFDIKPVSIDVIAGESAD 2950 Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRH 473 F C + W + + + +T N L + + K DSG YTC A++ Sbjct: 2951 FECHVTGAQPMRVTWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDV 3010 Query: 474 GKYVWSGALLVDSP 487 GK + S L V P Sbjct: 3011 GKDMCSAQLSVKEP 3024 Score = 113 bits (273), Expect = 2e-23 Identities = 124/485 (25%), Positives = 187/485 (38%), Gaps = 24/485 (4%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P Q D+ P TL CR GS + WY+ GVL+ D + + + L+ Sbjct: 2836 PSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQMSFVDNVATLKI 2895 Query: 72 THGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130 + S +G Y C A+N GTA S T F ++P S G++ EC Sbjct: 2896 LQTDL-SHSGQYSCSASNPLGTASSTARLTAREPKKSPFFDIKPVSIDVIAGESADFEC- 2953 Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTR 189 G+ V W K+ + + G+ + V +L I + D+G+Y C A N G + Sbjct: 2954 HVTGAQPMRVTWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVG-K 3012 Query: 190 ESAIATLKIHIKPYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPL 246 + A L + P I + VA+ G S+ +C++ G P V+W R+ + Sbjct: 3013 DMCSAQLSVKEPPKFIKKLDASKVAKQGESIQLECKISGSPEIKVVWFRNDSELHESWKY 3072 Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306 V L ++ D G+Y CEA N VG S S L V PP P V Sbjct: 3073 NMSFVNSVALLTINEASAEDTGDYICEAHNGVGDASCSTALKVKAPPVFTQKPPPVGALK 3132 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV-FDGVTVLTINDTDKND 365 G+ C +G P + W V+ + + S K+ T+ FD T L I + + D Sbjct: 3133 GSDVILQCEISGTPPFEVVW-VKDRKQV----RSSKKFKITSKNFD--TSLHIFNLEAPD 3185 Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425 C A N GS T PP + TL + + P Sbjct: 3186 I-GEYHCKATNEVGSD----TCACTVKFKEPPRFVKKLSDASTLIGDPVELQAVVEGFQP 3240 Query: 426 EPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482 ++ +GE + ++ ++ N TL L + S SG Y C + G S L Sbjct: 3241 ISVVWLKDKGEVIRESENVRISFVDNIATLQLGSPEASQSGKYVCQIKNDAGMRECSAVL 3300 Query: 483 LVDSP 487 V P Sbjct: 3301 TVLEP 3305 Score = 110 bits (265), Expect = 2e-22 Identities = 124/481 (25%), Positives = 185/481 (38%), Gaps = 30/481 (6%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E PY ++Q V V A+L C+ G+P + WYKG + + + L Sbjct: 4620 EPPYFVKQLEPVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATCKMHFKNNVATL 4679 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRN-ATLHVAVLREEFRLEPESKQSAQGDTVVLE 128 T SD+G Y C A NS G S T+ L F + Q G VV E Sbjct: 4680 VFTQVD-SSDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFE 4738 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAG 187 C GS +V W K+G+ L + + +D L I ++ +G+Y C A N G Sbjct: 4739 C-AVSGSEPISVSWYKDGKPLKDSPNIQTSFLDNIATLNIFKTDRSLSGQYSCTATNPIG 4797 Query: 188 TRESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGG 241 + S + K P+ + A G S +C V G V W R G Sbjct: 4798 SASSGAKLILTEGKNPPFFDIPLAPMDAVVGESADLECHVTGTQPIKVTWAKDNREIRSG 4857 Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLS 298 GN + ++ + L + V D G+Y+C A N VG S + L + + PPS Sbjct: 4858 GNYQISYLE--NSAHLTIVKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKK 4915 Query: 299 -PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 +V GN + G T+ W N I P + + + +L Sbjct: 4916 LSETVEETEGNSFKLEGRVAGSQPITVAW--YKNNVEIHPTSNCE----IMFKNNALLLQ 4969 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417 + D+ C A N AGS+ + + + + PP+ + T Sbjct: 4970 VKRASMADA-GLYTCKATNDAGSALCTSSIVI--KEPKKPPVFDQHLAPVTASEGDSVQL 5026 Query: 418 PCTAICTPEPI-IAWYFEGEALIQNHRRNVT-NDGT--LVLKDLDKSDSGTYTCVASSRH 473 C + EPI I W G + + R + + GT L LK+ K+DSG Y C AS+ Sbjct: 5027 SC-HVQGSEPIRIQWLKAGREVKPSDRCSFSFASGTAMLELKETAKADSGDYVCKASNVA 5085 Query: 474 G 474 G Sbjct: 5086 G 5086 Score = 107 bits (258), Expect = 1e-21 Identities = 121/490 (24%), Positives = 192/490 (39%), Gaps = 30/490 (6%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P +++ D T Q TL GS ++ W KG ++ D + + G+ L Sbjct: 583 EPPTFVKKVDDFTALAGQTVTLQAAVRGSEPISVMWMKGQEVIKEDGKIKMSFSNGVAVL 642 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL--EPESKQSAQGDTVVL 127 ++ S G Y C A N G+ S + +++E ++ E Q GD L Sbjct: 643 TIPDVQI-SLGGKYTCLAENEAGSQTS----VGELIVKEPAKIIERAELIQVTAGDPATL 697 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAA 186 E G+PE W K+G+ L+ R+ + L A D+G+Y N Sbjct: 698 E-YTVSGTPELKPKWYKDGRPLVASKKYRISFKNNIAQLKFYSAELHDSGQYTFEISNEV 756 Query: 187 GTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 G+ E+ L I P +V + G + C++ G V W + G Sbjct: 757 GSSSCETTFTVLDRDIAPLFTKPLRNVDSVVGGACRLDCKIAGSLPMRVSWFKD-GKELT 815 Query: 245 PLGRVKVL---DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301 R ++ SL + V + D G ++C A NSVG+ +SG L V +PPS P S Sbjct: 816 ASDRYQIAFVEGTASLEISRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGS 875 Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361 +V G+ G T+ W +G++ ++ G Y + + L + Sbjct: 876 RDVLPGSAVCLKSAFQGSAPLTIKW-FKGDKELVSGGSC---YITKETSE--SSLELYAV 929 Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421 +DS T C N AGS L V P I +Q L C Sbjct: 930 KTSDS-GTYTCKVSNVAGSVECSADLFV----KEPATFIEKLEPSQLLKKGDGTQLACKV 984 Query: 422 ICTPEPIIAWYFEGEALIQNHRRNVT-NDGTLVLK--DLDKSDSGTYTCVASSRHGKYVW 478 TP I W+ L ++ + ++ + T VL+ D+ DSG Y C A + G Sbjct: 985 TGTPPIKITWFANDRELRESSKHKMSFAESTAVLRLTDVAIEDSGEYMCEAQNEAGSDHC 1044 Query: 479 SGALLV-DSP 487 +G ++V +SP Sbjct: 1045 TGIVIVKESP 1054 Score = 103 bits (248), Expect = 2e-20 Identities = 122/502 (24%), Positives = 193/502 (38%), Gaps = 42/502 (8%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I+ D + +PA C+ G+ + WY + + + L Sbjct: 6 PAIVTPLQDTVTSEGRPARFQCQVSGTDLK-VSWYCKDKKIKPSRFFRMTQFEDTYQLEI 64 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHV----AVLRE--------EFRLEPESKQS 119 D G Y A N+ G S ATL + ++L E E + P K+ Sbjct: 65 AEA-YPEDEGTYAFVANNAVGQVSS-TATLRLEAPESILHERIGQQIEMEMKAAPVIKRR 122 Query: 120 AQGDTVVLECLPP-----RGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQT 173 + V L L +G+P W K G+ + + + +L I + Sbjct: 123 IEPLEVALGHLAKFTCEIQGAPNVRFQWFKAGREIYESDKCSIRSSNYVSSLEILRTQVV 182 Query: 174 DAGRYQCIARNAAGTRESAIATLKIH--IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231 D G Y C A N G+ S ATL + P ++ P+ + G + F C V G P+ Sbjct: 183 DCGEYTCKASNEYGS-VSCTATLTVTEAYPPTFLSRPKALTTFVGKAAKFLCTVSGTPVI 241 Query: 232 DVLWRRSAGG-GNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 +++W++ P RV D+ SL L N+ + D G YSC+A N GA LT+ Sbjct: 242 EIIWQKDGAALSPSPDCRVTDADNKHSLELSNLTVQDRGIYSCKASNKFGADICQAELTI 301 Query: 290 YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349 D P +V C + T+ WS +G + + K + Sbjct: 302 IDKPHFIKELEAVQSAINKKIHLECQVDEDRKVTITWSKDGQK------LPAGKDYKIYF 355 Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN-GPSNQT 408 D + L I DS T C+A N AGSS + V PP + PS Sbjct: 356 EDKIASLEIPLAKLKDS-GTYTCTASNEAGSSSSSAAVAVR----EPPSFVKKVDPSYLM 410 Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN---VTNDGTLVLKDLDKSDSGTY 465 LP +S A C +P + W+ + L +++ V ++ L + D+ DSGTY Sbjct: 411 LPGES-ARLHCKLKGSPVIQVTWFKNNKELSESNTVRMSFVNSEAILDITDVKVDDSGTY 469 Query: 466 TCVASSRHGKYVWSGALLVDSP 487 +C A++ G S +++ P Sbjct: 470 SCEATNDVGSDSCSTEVVIKEP 491 Score = 103 bits (246), Expect = 4e-20 Identities = 117/490 (23%), Positives = 184/490 (37%), Gaps = 23/490 (4%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 VT E P I++ + R A GS + W K + D + + Sbjct: 1141 VTLREPPSFIKKIEATSSLRGGTAAFQATLKGSLPITVTWLKDNDEITEDDNIRMTFENN 1200 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 + L + V D G Y C+A N G R +A L V E S QGD Sbjct: 1201 VASLYLSGIEVKHD-GKYVCQAKNDAGIQRC-SALLSVKEPATIME-EAVSIDVTQGDPA 1257 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARN 184 L+ + G+ E + W K+GQ L ++ + D +++ I + D+G Y +N Sbjct: 1258 TLQ-VKFSGTKEISAKWFKDGQELTLGPKYKISVTDTVSILKIISTEKKDSGEYTFEVQN 1316 Query: 185 AAGTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242 G +++I L + I P + + GS + +C V G + W + Sbjct: 1317 DVGRSSCKASINVLDLIIPPSFTKKLRKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEI 1376 Query: 243 NMPLGRVKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300 + D + L + + D G Y+C A N G SG+LTV +PP P Sbjct: 1377 SASDKHKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHSQCSGHLTVKEPPYFVEKPQ 1436 Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360 S +V G + G T+ W + + PG +R + D T+L + Sbjct: 1437 SQDVNPGTRVQLKALVGGTAPMTIKWFKDNKE--LHPGAARSVWKD----DTSTILELFS 1490 Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420 DS T +C N G++ + + V PP I L F C Sbjct: 1491 AKAADS-GTYICQLSNDVGTTSSKATIFV----KEPPQFIKKPSPVLVLRNGQSTTFECQ 1545 Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVT-NDG--TLVLKDLDKSDSGTYTCVASSRHGKYV 477 TPE ++WY +G + + ++ DG T + + +SGTY C A + G Sbjct: 1546 VTGTPEIRVSWYLDGNEITDLRKYGISFVDGLATFQISNARVENSGTYVCEARNDAGTAS 1605 Query: 478 WSGALLVDSP 487 S L V P Sbjct: 1606 CSIELKVKEP 1615 Score = 103 bits (246), Expect = 4e-20 Identities = 118/510 (23%), Positives = 188/510 (36%), Gaps = 30/510 (5%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 L C+ GS +I W+ +VS + + L+ + SD G Y C A N Sbjct: 2480 LECKVAGSSPISIAWFHEKTKIVSGAKYQTTFSDNVCTLQL-NSLDSSDMGSYTCVAANV 2538 Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150 G+ R A L V F EPE + G + + RG+P V W + + L+ Sbjct: 2539 AGSDECR-ALLTVQE-PPSFVKEPEPLEVLPGKNITFTSVI-RGTPPFKVGWFRGARELV 2595 Query: 151 FDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209 ++ D L + + + +G Y C+ N AG + S L + + Sbjct: 2596 KGNRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAG-QASCTTRLFVKEPATFVKKLS 2654 Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA---D 266 D + G S+ + G V W++ G P R ++ + ++ + D Sbjct: 2655 DHSVEPGKSIILEGTYTGTLPISVTWKKD-GVSITPSERCNIVTTEKTCILEILSSTKGD 2713 Query: 267 EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326 G YSCE EN G + ++ +PP + G+ C G PE T+ W Sbjct: 2714 AGHYSCEIENEAGRDACDALVSTLEPPYFVTELEPLEASVGDSVSLQCQVAGTPEITVSW 2773 Query: 327 SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386 +G+ + S +Y T + V L N NDS C A N G++ K Sbjct: 2774 -FKGDTKL----RSTPEYR-TYFTNNVATLVFNKVSINDS-GEYTCMAENSIGTA--ASK 2824 Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT---PEPI-IAWYFEGEALIQNH 442 + + PP + Q I+ P T C PI + WY +G L + Sbjct: 2825 TIFRIQERQLPPSF----ARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDE 2880 Query: 443 RRN---VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAAD 499 V N TL + D S SG Y+C AS+ G + L P + Sbjct: 2881 NLQMSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSTARLTAREPKKSPFFDIKPVS 2940 Query: 500 VSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529 + + G H + ++WS++NK Sbjct: 2941 IDVIAGESADFECHVTGAQPMRVTWSKDNK 2970 Score = 101 bits (243), Expect = 9e-20 Identities = 116/488 (23%), Positives = 185/488 (37%), Gaps = 27/488 (5%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDT-HRSILPAGGLF 67 E P I++ +VT AT GSP +I W K +L +D H S + Sbjct: 1707 EPPSFIKKIENVTTVLKSSATFQSTVAGSPPISITWLKDDQILEENDNVHISFEDSVATL 1766 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127 +R+ HS G Y C+A N G R A L V + + +S + D V L Sbjct: 1767 QVRSVDNG-HS--GRYTCQAKNESGIERCY-AFLLVQEPAQIIE-KAKSVDVTEKDPVTL 1821 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAA 186 EC+ G+PE V W K+G+ ++ M + + IQ + D+G+Y N Sbjct: 1822 ECVVA-GTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDF 1880 Query: 187 GTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 G+ ++ + L I P + GSS+ +C+V G W + + Sbjct: 1881 GSSSCDAYLRVLDQDIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEIST 1940 Query: 245 PLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302 V + SL + N+ L D Y+C+ N G + SG LTV +PPS + P Sbjct: 1941 SAKYRLVCHENTVSLEVSNLELEDTANYTCKVSNVAGDNACSGILTVKEPPSFLVKPERQ 2000 Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362 + F G P + W + + P +T+ + +V D+ Sbjct: 2001 QAIPDSTVEFKAVLKGTPPFKIKWLKDDVELVSGPKCFIGLEGSTSFLNLYSV----DSS 2056 Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422 K C N GS L VT PP + +++ + A C Sbjct: 2057 KT---GQYTCQVTNDVGSDSCTTMLLVT----EPPKFVKKLEASKIIKAGDSARLECKIT 2109 Query: 423 CTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479 +PE + WY L + + +T + + + L DSG + C A + G S Sbjct: 2110 GSPEIQVVWYRNEHELTASDKYQMTFIDSVAVIQMNSLGTEDSGDFICEAQNPAGSTSCS 2169 Query: 480 GALLVDSP 487 ++V P Sbjct: 2170 TKVIVKEP 2177 Score = 101 bits (243), Expect = 9e-20 Identities = 118/527 (22%), Positives = 191/527 (36%), Gaps = 26/527 (4%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P + + D + L CR GS ++ W+ G ++S A + L Sbjct: 3402 PSFVRRLKDTSATLGASVVLECRVSGSAPISVGWFLDGNEIISSPKCQSSFADNVCTLTL 3461 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131 + SD G Y C A N G S +A L V F P+S + G ++ + Sbjct: 3462 S-SLEPSDTGAYTCVAANVAGQDES-SAVLTVQE-PPSFEQTPDSVEVLPGMSLTFTSVI 3518 Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRE 190 RG+P V W K + L+ + L D L + + +G Y C+ N AG Sbjct: 3519 -RGTPPFKVKWFKGSRELVSGEACTISLEDFVTELELLEVEPGQSGDYSCLVTNDAG--- 3574 Query: 191 SAIATLKIHIKP--YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLG 247 SA T + +K + D +TGS + + G P V W ++ P Sbjct: 3575 SASCTTHLFVKEPATFVKRLADTSVETGSPIVLEATYSGTPPISVSWMKNEYPLSQSPNC 3634 Query: 248 RVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306 + + S L + + D +Y+C EN G ++V +PP V Sbjct: 3635 GITTTEKSSILEILESTIEDYAQYACLIENEAGQDICEALVSVLEPPYFIEPLEHVEAAI 3694 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 G C G PE + W E + P + + V L IN D +D Sbjct: 3695 GEPITLQCKVDGTPEIRISWYKEHTKLRSAPA------YKMQFKNNVASLVINKVDHSDV 3748 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426 C A N G+ V + + + PP + + F C I E Sbjct: 3749 -GEYTCKAENSVGA--VASSAVLVIKERKLPPSFARKLKDVHETLGFPVAFECR-INGSE 3804 Query: 427 PI-IAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482 P+ ++WY +GE L + ++ + TL + D+S G Y C AS+ G S L Sbjct: 3805 PLQVSWYKDGELLKDDANLQMSFVHHVATLQILQTDQSHVGQYNCSASNPLGTASSSAKL 3864 Query: 483 LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529 ++ P + V G H + ++W+++N+ Sbjct: 3865 ILSEHEVPPFFDLKPVSVDLALGESGSFKCHVTGTAPIKITWAKDNR 3911 Score = 101 bits (242), Expect = 1e-19 Identities = 118/477 (24%), Positives = 189/477 (39%), Gaps = 29/477 (6%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFF 68 E P I + +TV +PA L G+ +++W K V+ ++ I + Sbjct: 2269 EPPKFISKLNSLTVVAGEPAELQASIEGAQPISVQWLKEKEEVIRESENIRISFVNNVAT 2328 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDTVVL 127 L+ ++AG Y C+ N G R ATL VL +E + G+T L Sbjct: 2329 LQFAKVEP-ANAGKYICQVKND-GGVRENMATL--TVLEPAVIIEKAGSMTVTVGETCAL 2384 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAA 186 EC G+PE +V W K+G+ L + + +L I + DAG Y +N Sbjct: 2385 EC-KVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLKILSVEKEDAGTYTFQVQNNV 2443 Query: 187 GTRESAIATLKIH---IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 G + S A + + + P +D G+S +C+V G + W Sbjct: 2444 G-KSSCTAVVDVSDRMVPPSFTRRLKDTGGVLGTSCILECKVAGSSPISIAWFHEKTKIV 2502 Query: 244 MPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301 D +L+L+++ +D G Y+C A N G+ LTV +PPS P Sbjct: 2503 SGAKYQTTFSDNVCTLQLNSLDSSDMGSYTCVAANVAGSDECRALLTVQEPPSFVKEPEP 2562 Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361 + V G FT G P + W G R ++ G + Y D V L + + Sbjct: 2563 LEVLPGKNITFTSVIRGTPPFKVGW-FRGARELV-KGNRCNIYFE----DTVAELELFNI 2616 Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421 D + S C N AG + +L V P + + P KS+ + T Sbjct: 2617 DISQS-GEYTCVVSNNAGQASCTTRLFV----KEPATFVKKLSDHSVEPGKSI-ILEGTY 2670 Query: 422 ICTPEPIIAWYFEGEALIQNHRRN-VTNDGTLVLKDLD--KSDSGTYTCVASSRHGK 475 T + W +G ++ + R N VT + T +L+ L K D+G Y+C + G+ Sbjct: 2671 TGTLPISVTWKKDGVSITPSERCNIVTTEKTCILEILSSTKGDAGHYSCEIENEAGR 2727 Score = 101 bits (242), Expect = 1e-19 Identities = 122/500 (24%), Positives = 199/500 (39%), Gaps = 37/500 (7%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P Q DV P C GS ++ WYK G + + + L Sbjct: 4718 PSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWYKDGKPLKDSPNIQTSFLDNIATLNI 4777 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDTVVLECL 130 S +G Y C ATN G+A S + F P + A G++ LEC Sbjct: 4778 FKTD-RSLSGQYSCTATNPIGSASSGAKLILTEGKNPPFFDIPLAPMDAVVGESADLEC- 4835 Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRM-HLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189 G+ V W K+ + + G+ ++ +L + +L I + D+G+Y C A N G + Sbjct: 4836 HVTGTQPIKVTWAKDNREIRSGGNYQISYLENSAHLTIVKVDKGDSGQYTCYAVNEVG-K 4894 Query: 190 ESAIATLKIH---IKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 +S A L I I P + V +T G+S + RV G V W ++ + P Sbjct: 4895 DSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNVEIH-P 4953 Query: 246 LGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP---PSINLSP 299 +++ + L++ +AD G Y+C+A N G+ + + + +P P + Sbjct: 4954 TSNCEIMFKNNALLLQVKRASMADAGLYTCKATNDAGSALCTSSIVIKEPKKPPVFDQHL 5013 Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359 V G+ + +C G + W G + P D+ + + G +L + Sbjct: 5014 APVTASEGDSVQLSCHVQGSEPIRIQWLKAGRE--VKPS---DRC-SFSFASGTAMLELK 5067 Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP----------IITNGPSNQTL 409 +T K DS + VC A N AGS + K+T+ P + P + + Sbjct: 5068 ETAKADSGD-YVCKASNVAGSDTSKCKVTIKEKPAAAPAAKKAAVDGKLFFVSEPQSIRV 5126 Query: 410 PIKSMAVFPCTAICTPEPIIAWYF-EGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTY 465 K+ A F P P + W + L Q R + G L ++D K+DSG Y Sbjct: 5127 VEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRILIHQKGDEAKLEIRDTTKTDSGLY 5186 Query: 466 TCVASSRHGKYVWSGALLVD 485 CVA ++HG+ + L VD Sbjct: 5187 RCVAFNKHGEIESNVNLQVD 5206 Score = 100 bits (239), Expect = 3e-19 Identities = 118/492 (23%), Positives = 192/492 (39%), Gaps = 35/492 (7%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P +++ D + P L G ++ W K V+ ++ + Sbjct: 3210 EPPRFVKKLSDASTLIGDPVELQAVVEGFQPISVVWLKDKGEVIRESENVRISFVDNIAT 3269 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLE 128 S +G Y C+ N G R + + VL +E PE G+ LE Sbjct: 3270 LQLGSPEASQSGKYVCQIKNDAGM---RECSAVLTVLEPATIVEKPEPMTVTTGNPFTLE 3326 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV---IQDARQTDAGRYQCIARNA 185 C+ G+PE + W K+G+ L SR H+ NL I A D G Y N Sbjct: 3327 CVVA-GTPELSAKWFKDGREL--SSGSRHHITFVRNLASLKIPSAEMNDKGLYTFEVENR 3383 Query: 186 AGTRESAIATLKIHIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 G + T+ +H+ P + +D A G+SV +CRV G V W Sbjct: 3384 VG---KSSCTVSVHVSDRVVPPSFVRRLKDTSATLGASVVLECRVSGSAPISVGWFLDGN 3440 Query: 241 GG-NMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298 + P + D+ +L L ++ +D G Y+C A N G +S LTV +PPS + Sbjct: 3441 EIISSPKCQSSFADNVCTLTLSSLEPSDTGAYTCVAANVAGQDESSAVLTVQEPPSFEQT 3500 Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358 P+SV V G FT G P + W +G+R ++ + ++ D VT L + Sbjct: 3501 PDSVEVLPGMSLTFTSVIRGTPPFKVKW-FKGSRELV-----SGEACTISLEDFVTELEL 3554 Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418 + + S C N AGS+ L V + P ++ ++ S V Sbjct: 3555 LEVEPGQS-GDYSCLVTNDAGSASCTTHLFV-----KEPATFVKRLADTSVETGSPIVLE 3608 Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNV-TNDGTLVLKDLDKS--DSGTYTCVASSRHGK 475 T TP ++W L Q+ + T + + +L+ L+ + D Y C+ + G+ Sbjct: 3609 ATYSGTPPISVSWMKNEYPLSQSPNCGITTTEKSSILEILESTIEDYAQYACLIENEAGQ 3668 Query: 476 YVWSGALLVDSP 487 + + V P Sbjct: 3669 DICEALVSVLEP 3680 Score = 89.4 bits (212), Expect = 5e-16 Identities = 110/465 (23%), Positives = 176/465 (37%), Gaps = 26/465 (5%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P + +P V L GS I+W+KG +VS I L Sbjct: 865 EPPSFVTKPGSRDVLPGSAVCLKSAFQGSAPLTIKWFKGDKELVSGGSCYITKETSESSL 924 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEF-RLEPESKQSAQGDTVVLE 128 + SD+G Y C+ +N G+ +A L V +LEP S+ +GD L Sbjct: 925 ELYAVKT-SDSGTYTCKVSNVAGSVEC-SADLFVKEPATFIEKLEP-SQLLKKGDGTQLA 981 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAG 187 C G+P + W N + L +M + ++ + D D+G Y C A+N AG Sbjct: 982 C-KVTGTPPIKITWFANDRELRESSKHKMSFAESTAVLRLTDVAIEDSGEYMCEAQNEAG 1040 Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247 + + + + PY + + V V G P ++ W + Sbjct: 1041 S-DHCTGIVIVKESPYFTKEFKSIEVLKEYDVMLLAEVAGTPPFEITWFKDNTTLRSGRK 1099 Query: 248 RVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305 L D SL++ + AD GEY C N VG+ + S +T+ +PPS + + Sbjct: 1100 YKTFLQDQLVSLQVLKFVAADAGEYQCRVTNEVGSSTCSARVTLREPPSFIKKIEATSSL 1159 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD-KN 364 G A F T G T+ W + + ++ D + V L ++ + K+ Sbjct: 1160 RGGTAAFQATLKGSLPITVTWLKDNDE------ITEDDNIRMTFENNVASLYLSGIEVKH 1213 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424 D + VC A N AG L+V + P I + + A T Sbjct: 1214 DGK--YVCQAKNDAGIQRCSALLSV-----KEPATIMEEAVSIDVTQGDPATLQVKFSGT 1266 Query: 425 PEPIIAWYFEGEALIQNHRRNVT-NDGTLVLK--DLDKSDSGTYT 466 E W+ +G+ L + ++ D +LK +K DSG YT Sbjct: 1267 KEISAKWFKDGQELTLGPKYKISVTDTVSILKIISTEKKDSGEYT 1311 Score = 39.1 bits (87), Expect = 0.72 Identities = 31/121 (25%), Positives = 56/121 (46%), Gaps = 12/121 (9%) Query: 122 GDTVVLECLPPRGSPEPNVY-WKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRY 178 G + + ECL SP + W K+G + + + DG + L I D + +DAG Y Sbjct: 8126 GSSAIFECLV---SPSTAITTWMKDGSNIR-ESPKHRFIADGKDRKLHIIDVQLSDAGEY 8181 Query: 179 QCIAR--NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 C+ R N T + + ++ ++ ++ T E+V G + C + + DV+WR Sbjct: 8182 TCVLRLGNKEKTSTAKLIVEELPVR-FVKTLEEEVTVVKGQPLYLSCELNKE--RDVVWR 8238 Query: 237 R 237 + Sbjct: 8239 K 8239 >UniRef50_Q4RY92 Cluster: Chromosome 3 SCAF14978, whole genome shotgun sequence; n=4; Vertebrata|Rep: Chromosome 3 SCAF14978, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 2222 Score = 136 bits (328), Expect = 5e-30 Identities = 144/545 (26%), Positives = 236/545 (43%), Gaps = 69/545 (12%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYK--GGVLVVSDT---HRSILPAGGLFFLRATHG 74 ++T+A ++C G+ IRW G L S + + P G + G Sbjct: 1523 NITLAEGSDVYIHCNISGALQAKIRWITPDGTQLTTSQFSTGNNRVFPNGTIHI----PG 1578 Query: 75 RVHSDAGVYWCEATNSYGTAR-----SRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 + G Y C ATNS ++R S +L + R F P+ G++++L+C Sbjct: 1579 LTKKNTGRYECLATNSLVSSRRVVMLSLKRSLSSSKARVVFS-SPQRTDVIYGESLLLDC 1637 Query: 130 LPPRGSPEPNVYWKKNGQTLL---FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186 + G P P + W+ + L+ + DSR+ ++ G + I+ + D+G Y C+ARN Sbjct: 1638 VTT-GEPTPRIIWRTPSKKLVDAQYSFDSRIMVLANGTIAIRSVTEKDSGDYLCVARNKI 1696 Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 G + + + + +P I + +Q G + C G P P++ W G Sbjct: 1697 GD-DYILLRVNVMTRPAKIKQKQQHSSQEVIYGGDLKVDCVASGLPNPEISWALPDGTMV 1755 Query: 244 MPL-------GRVK---VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY--- 290 P+ GR + V D+G+L ++V + +EG+Y+C AEN +G + V Sbjct: 1756 DPVKTRDSSGGRSRRYVVFDNGTLYFNDVGMPEEGDYTCYAENKLGKDEMKVTVKVKVAT 1815 Query: 291 DPPSI-NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349 +PP I + N V G+ TC A G P P + W +R I + DK+ + Sbjct: 1816 NPPKIQDKKQNLVKGFYGDTVVLTCNAKGEPLPVITWISPTSRVIT---STVDKHQI--L 1870 Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT--NGPSN- 406 DG L I + D N C A N AG F +L V P+I +G SN Sbjct: 1871 NDGT--LIIQKVQRFDGGN-YSCVARNNAGQDFKVTRLEVLVTS----PVINGLSGTSNI 1923 Query: 407 --QTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI----QNHRRNVTNDGTLVLKDLDKS 460 T + C A TP P + W G ++ ++R V +GTL ++ L ++ Sbjct: 1924 ITVTAVQDQIKFLDCVAKGTPTPRVMWLLPGNVILPAPYNSNRMTVHQNGTLEIRSLKRT 1983 Query: 461 DSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSV 520 D+G TC+A + G+ L V+ +N AA+ S + GP T+ ++ V T + Sbjct: 1984 DAGKLTCIARNEGGEV----RLSVNLSVN------EAAEKSHISGPKTQSLSLTVGST-M 2032 Query: 521 TLSWS 525 TL+ S Sbjct: 2033 TLNCS 2037 Score = 119 bits (287), Expect = 4e-25 Identities = 129/512 (25%), Positives = 212/512 (41%), Gaps = 46/512 (8%) Query: 12 PYIIEQPL--DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT--------HRSIL 61 P +I QP DVTV L+C G P+P + W + V+ H SIL Sbjct: 1413 PPLILQPRQRDVTVNLGGKIHLDCAVEGHPTPRVTWVLPNRVHVAPVPHGTPSWQHVSIL 1472 Query: 62 PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA-VLREEFRLEPESKQSA 120 G L A +D G+Y C +++ G+ +HV+ +L E + + ++ A Sbjct: 1473 SNGTLRISEAAF----ADRGIYKCIGSSTAGSDAVL-VRVHVSGILSEVQQTQYQNITLA 1527 Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGD---SRMHLVDGGNLVIQDARQTDAGR 177 +G V + C G+ + + W T L + G + I + + GR Sbjct: 1528 EGSDVYIHC-NISGALQAKIRWITPDGTQLTTSQFSTGNNRVFPNGTIHIPGLTKKNTGR 1586 Query: 178 YQCIARNA-AGTRESAIATLKIHIKP----YLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232 Y+C+A N+ +R + +LK + + + P+ G S+ C G+P P Sbjct: 1587 YECLATNSLVSSRRVVMLSLKRSLSSSKARVVFSSPQRTDVIYGESLLLDCVTTGEPTPR 1646 Query: 233 VLWR----RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288 ++WR + R+ VL +G++ + +V D G+Y C A N +G + Sbjct: 1647 IIWRTPSKKLVDAQYSFDSRIMVLANGTIAIRSVTEKDSGDYLCVARNKIGDDYILLRVN 1706 Query: 289 VYDPPSI---NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRD--- 342 V P+ +S V G + C A+G P P + W++ T++ P +RD Sbjct: 1707 VMTRPAKIKQKQQHSSQEVIYGGDLKVDCVASGLPNPEISWALPDG-TMVDPVKTRDSSG 1765 Query: 343 -KYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401 + VFD T L ND + + C A N G + K+TV PP I Sbjct: 1766 GRSRRYVVFDNGT-LYFNDVGMPEEGD-YTCYAENKLGKDEM--KVTVKVKVATNPPKIQ 1821 Query: 402 NGPSNQTLPIKS-MAVFPCTAICTPEPIIAWYFEGEALIQN--HRRNVTNDGTLVLKDLD 458 + N V C A P P+I W +I + + + NDGTL+++ + Sbjct: 1822 DKKQNLVKGFYGDTVVLTCNAKGEPLPVITWISPTSRVITSTVDKHQILNDGTLIIQKVQ 1881 Query: 459 KSDSGTYTCVASSRHGK--YVWSGALLVDSPI 488 + D G Y+CVA + G+ V +LV SP+ Sbjct: 1882 RFDGGNYSCVARNNAGQDFKVTRLEVLVTSPV 1913 Score = 108 bits (259), Expect = 1e-21 Identities = 123/496 (24%), Positives = 199/496 (40%), Gaps = 49/496 (9%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV----SDTHRSIL 61 ++S +A + P V + L+C G P+P I W +V S R ++ Sbjct: 1610 LSSSKARVVFSSPQRTDVIYGESLLLDCVTTGEPTPRIIWRTPSKKLVDAQYSFDSRIMV 1669 Query: 62 PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121 A G +R+ D+G Y C A N G L V V+ +++ + + S+Q Sbjct: 1670 LANGTIAIRSV---TEKDSGDYLCVARNKIG---DDYILLRVNVMTRPAKIKQKQQHSSQ 1723 Query: 122 ----GDTVVLECLPPRGSPEPNVYWKKNGQTLL--------FDGDSRMHLV-DGGNLVIQ 168 G + ++C+ G P P + W T++ G SR ++V D G L Sbjct: 1724 EVIYGGDLKVDCV-ASGLPNPEISWALPDGTMVDPVKTRDSSGGRSRRYVVFDNGTLYFN 1782 Query: 169 DARQTDAGRYQCIARNAAGTRESAIAT-LKIHIKPYLITGPED--VVAQTGSSVTFQCRV 225 D + G Y C A N G E + +K+ P I + V G +V C Sbjct: 1783 DVGMPEEGDYTCYAENKLGKDEMKVTVKVKVATNPPKIQDKKQNLVKGFYGDTVVLTCNA 1842 Query: 226 GGDPLPDVLW-RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSA 283 G+PLP + W ++ + + ++L+DG+L + V D G YSC A N+ G Sbjct: 1843 KGEPLPVITWISPTSRVITSTVDKHQILNDGTLIIQKVQRFDGGNYSCVARNNAGQDFKV 1902 Query: 284 SGYLTVYDPPSIN-LSPNS----VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPG 338 + + P IN LS S V + C A G P P + W + GN +I P Sbjct: 1903 TRLEVLVTSPVINGLSGTSNIITVTAVQDQIKFLDCVAKGTPTPRVMWLLPGN--VILPA 1960 Query: 339 MSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398 + T +G L I + D+ + C A N G + L+V ++ Sbjct: 1961 -PYNSNRMTVHQNG--TLEIRSLKRTDA-GKLTCIARNEGGEVRLSVNLSVNEAAEKSH- 2015 Query: 399 IITNGPSNQ--TLPIKSMAVFPCTAICTPEPIIAWYF-EGEAL---IQNHRRNVTNDGTL 452 +GP Q +L + S C++ P + W G L Q + DG+L Sbjct: 2016 --ISGPKTQSLSLTVGSTMTLNCSSEGAHLPRVIWILPNGTPLNSGAQLSKFFNRPDGSL 2073 Query: 453 VLKDLDKSDSGTYTCV 468 ++ + S++GTY C+ Sbjct: 2074 IITNPSVSEAGTYRCL 2089 Score = 102 bits (244), Expect = 7e-20 Identities = 116/499 (23%), Positives = 189/499 (37%), Gaps = 57/499 (11%) Query: 31 LNCRAGGSPSPAIRWYK--GGVLVVSDT--HRSILPAGGLFFLRATHGRVHSDAGVYWCE 86 L C A G P P + W K G ++ +T HR + G +R T D G Y C+ Sbjct: 1337 LPCEADGEPRPFLSWTKVVSGTVIAQNTRVHRFEVHPNGTLTIRNTQ---PMDGGEYLCK 1393 Query: 87 ATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSA--QGDTVVLECLPPRGSPEPNVYW- 142 N +GT +V +L + L+P + G + L+C G P P V W Sbjct: 1394 VQNQHGT---DTMVANVVILSQPPLILQPRQRDVTVNLGGKIHLDC-AVEGHPTPRVTWV 1449 Query: 143 ---KKNGQTLLFDGDSRMH--LVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197 + + + S H ++ G L I +A D G Y+CI + AG S ++ Sbjct: 1450 LPNRVHVAPVPHGTPSWQHVSILSNGTLRISEAAFADRGIYKCIGSSTAG---SDAVLVR 1506 Query: 198 IHIKPYLI----TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG----GGNMPLGRV 249 +H+ L T +++ GS V C + G + W G G Sbjct: 1507 VHVSGILSEVQQTQYQNITLAEGSDVYIHCNISGALQAKIRWITPDGTQLTTSQFSTGNN 1566 Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENS------VGAVSASGYLTVYDPPSINLSPNSVN 303 +V +G++ + + + G Y C A NS V +S L+ + SP + Sbjct: 1567 RVFPNGTIHIPGLTKKNTGRYECLATNSLVSSRRVVMLSLKRSLSSSKARVVFSSPQRTD 1626 Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363 V G C TG P P + W ++ ++ S D + + ++ + D Sbjct: 1627 VIYGESLLLDCVTTGEPTPRIIWRTP-SKKLVDAQYSFDSRIMVLANGTIAIRSVTEKDS 1685 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP-SNQTLPIKSMAVFPCTAI 422 D +C A N G ++ ++ V + RP I S+Q + C A Sbjct: 1686 GD----YLCVARNKIGDDYILLRVNVMT---RPAKIKQKQQHSSQEVIYGGDLKVDCVAS 1738 Query: 423 CTPEPIIAWYFEGEALI-----------QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471 P P I+W ++ ++ R V ++GTL D+ + G YTC A + Sbjct: 1739 GLPNPEISWALPDGTMVDPVKTRDSSGGRSRRYVVFDNGTLYFNDVGMPEEGDYTCYAEN 1798 Query: 472 RHGKYVWSGALLVDSPINP 490 + GK + V NP Sbjct: 1799 KLGKDEMKVTVKVKVATNP 1817 Score = 102 bits (244), Expect = 7e-20 Identities = 112/466 (24%), Positives = 198/466 (42%), Gaps = 45/466 (9%) Query: 31 LNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRATHGRVH-SDAGV-----Y 83 ++C A G P+P I W G +V R ++ +G ++ +D G+ Y Sbjct: 1733 VDCVASGLPNPEISWALPDGTMVDPVKTRDSSGGRSRRYVVFDNGTLYFNDVGMPEEGDY 1792 Query: 84 WCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG---DTVVLECLPPRGSPEPNV 140 C A N G + T+ V V +++ + + +G DTVVL C +G P P + Sbjct: 1793 TCYAENKLGKDEMK-VTVKVKVATNPPKIQDKKQNLVKGFYGDTVVLTC-NAKGEPLPVI 1850 Query: 141 YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200 W ++ + +++ G L+IQ ++ D G Y C+ARN AG ++ + L++ + Sbjct: 1851 TWISPTSRVITSTVDKHQILNDGTLIIQKVQRFDGGNYSCVARNNAG-QDFKVTRLEVLV 1909 Query: 201 -KPYL--ITGPEDVVAQTG--SSVTF-QCRVGGDPLPDVLWRRSAGGGNMPL----GRVK 250 P + ++G +++ T + F C G P P V+W G +P R+ Sbjct: 1910 TSPVINGLSGTSNIITVTAVQDQIKFLDCVAKGTPTPRVMW-LLPGNVILPAPYNSNRMT 1968 Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLS---PNSVNVES 306 V +G+L + ++ D G+ +C A N G V S L+V + ++S S+++ Sbjct: 1969 VHQNGTLEIRSLKRTDAGKLTCIARNEGGEVRLSVNLSVNEAAEKSHISGPKTQSLSLTV 2028 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 G+ C++ G P + W + N T + G K+ DG ++T Sbjct: 2029 GSTMTLNCSSEGAHLPRVIW-ILPNGTPLNSGAQLSKFFNRP--DGSLIIT---NPSVSE 2082 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426 T C ++ G V K+T+T R P I S + I + C + E Sbjct: 2083 AGTYRCLWRDFQG--LVERKITLT--PGRKPEITNRYNSPISTMIGERLLLHC--LTNSE 2136 Query: 427 PI-IAWYFEGEALIQN----HRRNVTNDGTLVLKDLDKSDSGTYTC 467 P+ + W ++ R NV ++GTL + + D G+Y C Sbjct: 2137 PLRLTWTLPSGVVLNRPQKAGRYNVLSNGTLAIHQISTYDRGSYVC 2182 Score = 89.8 bits (213), Expect = 4e-16 Identities = 89/376 (23%), Positives = 145/376 (38%), Gaps = 26/376 (6%) Query: 119 SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD---GGNLVIQDARQTDA 175 +A+ +T V G P P + W K + ++R+H + G L I++ + D Sbjct: 1328 TAKAETDVQLPCEADGEPRPFLSWTKVVSGTVIAQNTRVHRFEVHPNGTLTIRNTQPMDG 1387 Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDV 233 G Y C +N GT ++ +A + I +P LI P DV G + C V G P P V Sbjct: 1388 GEYLCKVQNQHGT-DTMVANVVILSQPPLILQPRQRDVTVNLGGKIHLDCAVEGHPTPRV 1446 Query: 234 LW--RRSAGGGNMPLG-----RVKVLDDGSLRLDNVILADEGEYSCEAENSVG--AVSAS 284 W +P G V +L +G+LR+ AD G Y C ++ G AV Sbjct: 1447 TWVLPNRVHVAPVPHGTPSWQHVSILSNGTLRISEAAFADRGIYKCIGSSTAGSDAVLVR 1506 Query: 285 GYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344 +++ ++ + G+ C +G + + W + S Sbjct: 1507 VHVSGILSEVQQTQYQNITLAEGSDVYIHCNISGALQAKIRWITPDGTQLTTSQFSTGN- 1565 Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV-TSDDDRPPPIITNG 403 VF T+ T KN R C A N SS L++ S ++ + Sbjct: 1566 --NRVFPNGTIHIPGLTKKNTGR--YECLATNSLVSSRRVVMLSLKRSLSSSKARVVFSS 1621 Query: 404 PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ-----NHRRNVTNDGTLVLKDLD 458 P + + C P P I W + L+ + R V +GT+ ++ + Sbjct: 1622 PQRTDVIYGESLLLDCVTTGEPTPRIIWRTPSKKLVDAQYSFDSRIMVLANGTIAIRSVT 1681 Query: 459 KSDSGTYTCVASSRHG 474 + DSG Y CVA ++ G Sbjct: 1682 EKDSGDYLCVARNKIG 1697 Score = 76.6 bits (180), Expect = 4e-12 Identities = 72/269 (26%), Positives = 116/269 (43%), Gaps = 17/269 (6%) Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS---DTHRSILPAGGLFFLRATHGR 75 + VT + Q L+C A G+P+P + W G +++ +++R + G +R+ Sbjct: 1924 ITVTAVQDQIKFLDCVAKGTPTPRVMWLLPGNVILPAPYNSNRMTVHQNGTLEIRSLK-- 1981 Query: 76 VHSDAGVYWCEATNSYGTAR-SRNATLHVAVLREEFR-LEPESKQSAQGDTVVLECLPPR 133 +DAG C A N G R S N +++ A + + +S G T+ L C Sbjct: 1982 -RTDAGKLTCIARNEGGEVRLSVNLSVNEAAEKSHISGPKTQSLSLTVGSTMTLNC-SSE 2039 Query: 134 GSPEPNVYWKKNGQTLLFDGD--SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191 G+ P V W T L G S+ G+L+I + ++AG Y+C+ R+ G E Sbjct: 2040 GAHLPRVIWILPNGTPLNSGAQLSKFFNRPDGSLIITNPSVSEAGTYRCLWRDFQGLVER 2099 Query: 192 AIATLKIHIKPYLITGPEDVVA-QTGSSVTFQCRVGGDPLPDVLWRRSAGGG-NMP--LG 247 I TL KP + ++ G + C +PL + W +G N P G Sbjct: 2100 KI-TLTPGRKPEITNRYNSPISTMIGERLLLHCLTNSEPL-RLTWTLPSGVVLNRPQKAG 2157 Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAEN 276 R VL +G+L + + D G Y C N Sbjct: 2158 RYNVLSNGTLAIHQISTYDRGSYVCRVAN 2186 Score = 63.7 bits (148), Expect = 3e-08 Identities = 69/285 (24%), Positives = 111/285 (38%), Gaps = 21/285 (7%) Query: 201 KPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG----NMPLGRVKVLDDG 255 KP + G + A+ + V C G+P P + W + G N + R +V +G Sbjct: 1316 KPRITKGSFQTFTAKAETDVQLPCEADGEPRPFLSWTKVVSGTVIAQNTRVHRFEVHPNG 1375 Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVNVESGNVARFT 313 +L + N D GEY C+ +N G + + + P + L P V V G Sbjct: 1376 TLTIRNTQPMDGGEYLCKVQNQHGTDTMVANVVILSQPPLILQPRQRDVTVNLGGKIHLD 1435 Query: 314 CTATGRPEPTMFWSVEGNRTII--FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371 C G P P + W V NR + P + H + + +G L I++ D R Sbjct: 1436 CAVEGHPTPRVTW-VLPNRVHVAPVPHGTPSWQHVSILSNG--TLRISEAAFAD-RGIYK 1491 Query: 372 CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431 C + AGS V ++ V+ + N TL S C + I W Sbjct: 1492 CIGSSTAGSDAVLVRVHVSGILSE---VQQTQYQNITLAEGSDVYIHCNISGALQAKIRW 1548 Query: 432 YF-EGEALIQNH----RRNVTNDGTLVLKDLDKSDSGTYTCVASS 471 +G L + V +GT+ + L K ++G Y C+A++ Sbjct: 1549 ITPDGTQLTTSQFSTGNNRVFPNGTIHIPGLTKKNTGRYECLATN 1593 Score = 55.2 bits (127), Expect = 1e-05 Identities = 49/167 (29%), Positives = 71/167 (42%), Gaps = 17/167 (10%) Query: 31 LNCRAGGSPSPAIRWY-----KGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85 LNC S P I+W K S +R + GG ++A H+D G+Y+C Sbjct: 378 LNCNVHSSGHPVIQWTLPDGSKVEAPYSSPDNRVSVSNGGQLVIKAVS---HTDTGIYYC 434 Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPESK---QSAQGDTVVLECLPPRGSPEPNVYW 142 A A H+ V E Q G + L C+ GSP+ VYW Sbjct: 435 TAKVQGDFA---VLPFHLTVQESSSPSPGEDVSPFQGFAGKPISLPCI-TFGSPDAEVYW 490 Query: 143 -KKNGQTLLFDGD-SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 + + + F G+ SR H++ G L I + +D+G Y+CIA N G Sbjct: 491 ILPSSKIVSFHGNSSRAHVLLNGTLHIPQTQLSDSGHYKCIAINQHG 537 Score = 47.2 bits (107), Expect = 0.003 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 18/137 (13%) Query: 154 DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP---ED 210 D+R+ + +GG LVI+ TD G Y C A+ + A L H+ + P ED Sbjct: 408 DNRVSVSNGGQLVIKAVSHTDTGIYYCTAK-----VQGDFAVLPFHLTVQESSSPSPGED 462 Query: 211 V---VAQTGSSVTFQCRVGGDPLPDVLW-----RRSAGGGNMPLGRVKVLDDGSLRLDNV 262 V G ++ C G P +V W + + GN R VL +G+L + Sbjct: 463 VSPFQGFAGKPISLPCITFGSPDAEVYWILPSSKIVSFHGNS--SRAHVLLNGTLHIPQT 520 Query: 263 ILADEGEYSCEAENSVG 279 L+D G Y C A N G Sbjct: 521 QLSDSGHYKCIAINQHG 537 Score = 45.6 bits (103), Expect = 0.008 Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 8/87 (9%) Query: 395 RPPPIITNGPSNQTLPIKSMA--VFPCTAICTPEPIIAW--YFEGEALIQN---HRRNVT 447 R P IT G S QT K+ PC A P P ++W G + QN HR V Sbjct: 1314 RGKPRITKG-SFQTFTAKAETDVQLPCEADGEPRPFLSWTKVVSGTVIAQNTRVHRFEVH 1372 Query: 448 NDGTLVLKDLDKSDSGTYTCVASSRHG 474 +GTL +++ D G Y C ++HG Sbjct: 1373 PNGTLTIRNTQPMDGGEYLCKVQNQHG 1399 Score = 45.2 bits (102), Expect = 0.011 Identities = 40/185 (21%), Positives = 74/185 (40%), Gaps = 11/185 (5%) Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353 S N++ ++ G+ + C P + W++ + P S D + + + Sbjct: 360 SKNITRKVLSALLGSQSELNCNVHSSGHPVIQWTLPDGSKVEAPYSSPDNRVSVSNGGQL 419 Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413 + ++ TD C+A + + LTV + P P P Q K Sbjct: 420 VIKAVSHTDTG----IYYCTAKVQGDFAVLPFHLTV-QESSSPSPGEDVSPF-QGFAGKP 473 Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNH----RRNVTNDGTLVLKDLDKSDSGTYTCVA 469 +++ PC +P+ + W ++ H R +V +GTL + SDSG Y C+A Sbjct: 474 ISL-PCITFGSPDAEVYWILPSSKIVSFHGNSSRAHVLLNGTLHIPQTQLSDSGHYKCIA 532 Query: 470 SSRHG 474 ++HG Sbjct: 533 INQHG 537 Score = 41.9 bits (94), Expect = 0.10 Identities = 47/194 (24%), Positives = 72/194 (37%), Gaps = 13/194 (6%) Query: 213 AQTGSSVTFQCRVGGDPLPDVLWRRSAGGG-----NMPLGRVKVLDDGSLRLDNVILADE 267 A GS C V P + W G + P RV V + G L + V D Sbjct: 370 ALLGSQSELNCNVHSSGHPVIQWTLPDGSKVEAPYSSPDNRVSVSNGGQLVIKAVSHTDT 429 Query: 268 GEYSCEAENSVGAVSASGYLTVYD--PPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325 G Y C A+ +LTV + PS + +G C G P+ ++ Sbjct: 430 GIYYCTAKVQGDFAVLPFHLTVQESSSPSPGEDVSPFQGFAGKPISLPCITFGSPDAEVY 489 Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385 W + ++ + F G S A + +G L I T +DS + C A+N G + Sbjct: 490 WILPSSKIVSFHGNSS---RAHVLLNG--TLHIPQTQLSDSGH-YKCIAINQHGVDTLVT 543 Query: 386 KLTVTSDDDRPPPI 399 K T+ + P+ Sbjct: 544 KTTLIKQNGPIMPL 557 >UniRef50_UPI0000DB6C79 Cluster: PREDICTED: similar to PTK7 protein tyrosine kinase 7 isoform a precursor; n=1; Apis mellifera|Rep: PREDICTED: similar to PTK7 protein tyrosine kinase 7 isoform a precursor - Apis mellifera Length = 1112 Score = 134 bits (323), Expect = 2e-29 Identities = 138/488 (28%), Positives = 205/488 (42%), Gaps = 45/488 (9%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWY-KGGVLVVSDTHRSILPAG 64 V+S E + P D+ R +PA L+C + S ++W+ K + +D R++ G Sbjct: 211 VSSNETASVKVVPRDLIAKRGEPAVLHCVFEDADS--VQWFFKDMGPLETDDERTVFENG 268 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEP--ESKQSA 120 L A H D G Y C T S L +A L EP S+ + Sbjct: 269 TLVIRSAEH----RDQGFYSCHGDRGESTI-SYTVDLQIAYLMNLSAASFEPLLSSQVAV 323 Query: 121 QGDTVVLE--CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ-TDAGR 177 G+ L+ CL P G P P VYW+ ++ DS V L++ AR D G Sbjct: 324 VGEEQELQVSCLEPSGLPPPRVYWRDPKGHII--SDSGPVRVQDNTLIVAKARMGEDDGN 381 Query: 178 YQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGG--DPLPDVLW 235 Y C+A N AG + + A + I P LI+ PE++ G SVT C G P+ V W Sbjct: 382 YTCVAENMAGETDIS-AQVVISTPPTLISSPENLSVMEGDSVTMTCSYSGMDAPVTHVRW 440 Query: 236 RRSAGGGNMPLG--RVKVLD---DGSLRLDNVILADEGEYSCE--AENSVGAVSASGYLT 288 + G R +V D + +L L + L+D+G Y+CE + S LT Sbjct: 441 LKDGEPLKESGGPTRHRVTDHHGNVTLHLKSADLSDKGGYACEITTKGFPPIFSERAGLT 500 Query: 289 VYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348 V + + P +E G+ A+ C + G PT+ W EG+ FP +D + T Sbjct: 501 VEEKLKFSPQPVDKRLELGSTAKVPCKSQGATNPTVKWIKEGSGEE-FPKHVQD-INGTL 558 Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408 F+GV + + C A N GS + +++ D P T P N T Sbjct: 559 HFNGVL---------EEDKGRYTCIASNAQGS--INHTISI---DVVIAPKFTIQPQNPT 604 Query: 409 LPIKSMAVF-PCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYT 466 I+ V C A P+P I W + + N R V +G+L +K++ SD G Y Sbjct: 605 EAIEGYPVMLHCAAEGDPKPTIQWDRDSRMNNLNNSRFEVLGNGSLYIKEVYMSDEGKYG 664 Query: 467 CVASSRHG 474 C A + G Sbjct: 665 CTAGNSGG 672 Score = 112 bits (270), Expect = 5e-23 Identities = 92/309 (29%), Positives = 133/309 (43%), Gaps = 17/309 (5%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPA--IRWYKGGVLVVSD---THRSILPAGGL 66 P +I P +++V T+ C G +P +RW K G + T + G Sbjct: 405 PTLISSPENLSVMEGDSVTMTCSYSGMDAPVTHVRWLKDGEPLKESGGPTRHRVTDHHGN 464 Query: 67 FFLRATHGRVHSDAGVYWCE-ATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 L + SD G Y CE T + S A L V + +F +P K+ G T Sbjct: 465 VTLHLKSADL-SDKGGYACEITTKGFPPIFSERAGLTVEE-KLKFSPQPVDKRLELGSTA 522 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARN 184 + C +G+ P V W K G F H+ D G L + D GRY CIA N Sbjct: 523 KVPC-KSQGATNPTVKWIKEGSGEEFP----KHVQDINGTLHFNGVLEEDKGRYTCIASN 577 Query: 185 AAGTRESAIATLKIHIKPYLITGPED-VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 A G+ I ++ + I P P++ A G V C GDP P + W R + N Sbjct: 578 AQGSINHTI-SIDVVIAPKFTIQPQNPTEAIEGYPVMLHCAAEGDPKPTIQWDRDSRMNN 636 Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303 + R +VL +GSL + V ++DEG+Y C A NS G L V D S++ N ++ Sbjct: 637 LNNSRFEVLGNGSLYIKEVYMSDEGKYGCTAGNSGGLKREEVQLNVKD-TSVDERVNHLS 695 Query: 304 VESGNVARF 312 +G+ RF Sbjct: 696 STAGDTYRF 704 Score = 105 bits (252), Expect = 7e-21 Identities = 122/544 (22%), Positives = 205/544 (37%), Gaps = 33/544 (6%) Query: 10 EAPYIIEQP-LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68 EA ++QP L + L C GS W++ V+ + R + L Sbjct: 121 EASVQLQQPKLPSAIRVGGEIELRCHVDGSGDIKYEWFRNRE-PVARSDRIEIKKKKLHV 179 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVV 126 RA V D+G+Y C A N G++ + + E ++ P + +G+ V Sbjct: 180 HRA----VAEDSGMYNCLAKNDAGSSPKMESFPLIVSSNETASVKVVPRDLIAKRGEPAV 235 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186 L C+ +V W L D R + + G LVI+ A D G Y C Sbjct: 236 LHCV---FEDADSVQWFFKDMGPLETDDERT-VFENGTLVIRSAEHRDQGFYSCHGDRGE 291 Query: 187 GTRESAIATLKIHIKPYLITGPEDV----VAQTGSSVTFQ--C-RVGGDPLPDVLWRRSA 239 T + ++ E + VA G Q C G P P V WR Sbjct: 292 STISYTVDLQIAYLMNLSAASFEPLLSSQVAVVGEEQELQVSCLEPSGLPPPRVYWRDPK 351 Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299 G G V+V D+ + + D+G Y+C AEN G S + + PP++ SP Sbjct: 352 GHIISDSGPVRVQDNTLIVAKARMGEDDGNYTCVAENMAGETDISAQVVISTPPTLISSP 411 Query: 300 NSVNVESGNVARFTCTATGRPEPT--MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 +++V G+ TC+ +G P + W +G G +R H G L Sbjct: 412 ENLSVMEGDSVTMTCSYSGMDAPVTHVRWLKDGEPLKESGGPTR---HRVTDHHGNVTLH 468 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417 + D +D + C + +T ++ + P ++ L + S A Sbjct: 469 LKSADLSD-KGGYACEITTKGFPPIFSERAGLTVEEKLK---FSPQPVDKRLELGSTAKV 524 Query: 418 PCTAICTPEPIIAWYFEGEA-LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476 PC + P + W EG H +++ +GTL + + D G YTC+AS+ G Sbjct: 525 PCKSQGATNPTVKWIKEGSGEEFPKHVQDI--NGTLHFNGVLEEDKGRYTCIASNAQGSI 582 Query: 477 VWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSIL 536 + + +D I P ++ G P D T+ W +++++ + + Sbjct: 583 --NHTISIDVVIAPKFTIQPQNPTEAIEGYPVMLHCAAEGDPKPTIQWDRDSRMNNLNNS 640 Query: 537 GYQV 540 ++V Sbjct: 641 RFEV 644 >UniRef50_Q4S2G4 Cluster: Chromosome undetermined SCAF14761, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF14761, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 912 Score = 134 bits (323), Expect = 2e-29 Identities = 117/431 (27%), Positives = 177/431 (41%), Gaps = 33/431 (7%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK--GGVLVVSDTHRSILPAGGLF 67 E P E P D+ + TL C A GSP P + W++ G ++ R + G Sbjct: 505 EDPLFSETPADLMAKIGENVTLRCSARGSPQPTVSWHRHDGRQILTGSRSRMVQLEDGHL 564 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127 ++ G SD G+Y CEA N +GT ++ ++ E P + +G ++ L Sbjct: 565 LIQ---GVWLSDEGLYVCEAKNPFGTIKTGARLSVTGLVPPEIHAGPYHYIANEGVSITL 621 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 C G P+P+V W G +L + + I DAG Y C + N G Sbjct: 622 FC-KSSGVPKPDVVW---GGSLSLGTMLPVSVHQMATFHIPHPTTDDAGIYVCTSTNPVG 677 Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247 I L ++ KP + + A G SVT C V G+P P+V W + +P+G Sbjct: 678 YASREI-QLSVNTKPRIQPAATLLKALIGQSVTLPCVVQGEPSPEVTWFHN----GLPVG 732 Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE-- 305 + + LR+ L D+G Y C A NS G ++ L + D PS P +E Sbjct: 733 ---IKNTTPLRIQKAKLNDQGTYKCVATNSAGQETSEIKLDILDAPSF-AEPGDALLEKV 788 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365 + C A G P P + W G I P S + + DG LTI+ + Sbjct: 789 ANTKVIIPCPAEGSPRPKIRWYRNGLE--IHPEQSSPELFVSE--DG--ALTISSASASH 842 Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425 S +C A N AGS + +L + D PP+ G + + + C P Sbjct: 843 S-GDFMCVATNEAGSVERKTRLKIEGD----PPVF--GIQEEKVRMNGSLTLACMTKGFP 895 Query: 426 EPIIAWYFEGE 436 EP I W+ +G+ Sbjct: 896 EPKIQWFKDGQ 906 Score = 128 bits (309), Expect = 9e-28 Identities = 106/373 (28%), Positives = 150/373 (40%), Gaps = 34/373 (9%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN-GQTLLFDGDSRMHLVDGGNLVIQ 168 F P + G+ V L C RGSP+P V W ++ G+ +L SRM ++ G+L+IQ Sbjct: 509 FSETPADLMAKIGENVTLRC-SARGSPQPTVSWHRHDGRQILTGSRSRMVQLEDGHLLIQ 567 Query: 169 DARQTDAGRYQCIARNAAGT-RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGG 227 +D G Y C A+N GT + A ++ + P + GP +A G S+T C+ G Sbjct: 568 GVWLSDEGLYVCEAKNPFGTIKTGARLSVTGLVPPEIHAGPYHYIANEGVSITLFCKSSG 627 Query: 228 DPLPDVLWRRSAGGGNMPLGR---VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSAS 284 P PDV+W GG++ LG V V + + + D G Y C + N VG S Sbjct: 628 VPKPDVVW-----GGSLSLGTMLPVSVHQMATFHIPHPTTDDAGIYVCTSTNPVGYASRE 682 Query: 285 GYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344 L+V P I + + G C G P P + W G I Sbjct: 683 IQLSVNTKPRIQPAATLLKALIGQSVTLPCVVQGEPSPEVTWFHNGLPVGI--------- 733 Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404 T L I ND + T C A N AG KL + P G Sbjct: 734 ------KNTTPLRIQKAKLND-QGTYKCVATNSAGQETSEIKLDILD----APSFAEPGD 782 Query: 405 SNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN---VTNDGTLVLKDLDKSD 461 + + + PC A +P P I WY G + V+ DG L + S Sbjct: 783 ALLEKVANTKVIIPCPAEGSPRPKIRWYRNGLEIHPEQSSPELFVSEDGALTISSASASH 842 Query: 462 SGTYTCVASSRHG 474 SG + CVA++ G Sbjct: 843 SGDFMCVATNEAG 855 Score = 92.3 bits (219), Expect = 7e-17 Identities = 74/278 (26%), Positives = 112/278 (40%), Gaps = 26/278 (9%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDGSLRL 259 P P D++A+ G +VT +C G P P V W R G + R ++ L+DG L + Sbjct: 507 PLFSETPADLMAKIGENVTLRCSARGSPQPTVSWHRHDGRQILTGSRSRMVQLEDGHLLI 566 Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYD--PPSINLSPNSVNVESGNVARFTCTAT 317 V L+DEG Y CEA+N G + L+V PP I+ P G C ++ Sbjct: 567 QGVWLSDEGLYVCEAKNPFGTIKTGARLSVTGLVPPEIHAGPYHYIANEGVSITLFCKSS 626 Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377 G P+P + W + + P H A F T D VC++ N Sbjct: 627 GVPKPDVVWGGSLSLGTMLP----VSVHQMATFHIPHPTT-------DDAGIYVCTSTNP 675 Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437 G + +L+V + P I + I PC P P + W+ G Sbjct: 676 VGYASREIQLSVNT-----KPRIQPAATLLKALIGQSVTLPCVVQGEPSPEVTWFHNGLP 730 Query: 438 LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 + + N L ++ +D GTY CVA++ G+ Sbjct: 731 V------GIKNTTPLRIQKAKLNDQGTYKCVATNSAGQ 762 Score = 49.6 bits (113), Expect = 5e-04 Identities = 51/226 (22%), Positives = 87/226 (38%), Gaps = 40/226 (17%) Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTI--------------IFPG---------MSRDK 343 G+ RF C+A+G P P +FWS GN + +FPG +D Sbjct: 381 GDEIRFVCSASGSPTPQLFWS-HGNTFLTNRLRYITDQYCLCMFPGEFEVGSTLFAGQDD 439 Query: 344 YHATAVFDGVTVLT------INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR-- 395 YH T GV + + + + T+ + + T+ SD + Sbjct: 440 YHGTLHIRGVQKVDAGQYTCVASSPAGTATGTVSLKVGGESAFQCFNTEPTLPSDCTQRR 499 Query: 396 -----PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY-FEGEALIQNHRRNVTN- 448 P+ + P++ I C+A +P+P ++W+ +G ++ R + Sbjct: 500 FSPLTEDPLFSETPADLMAKIGENVTLRCSARGSPQPTVSWHRHDGRQILTGSRSRMVQL 559 Query: 449 -DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIH 493 DG L+++ + SD G Y C A + G L V + P IH Sbjct: 560 EDGHLLIQGVWLSDEGLYVCEAKNPFGTIKTGARLSVTGLVPPEIH 605 >UniRef50_O94856 Cluster: Neurofascin precursor; n=64; Euteleostomi|Rep: Neurofascin precursor - Homo sapiens (Human) Length = 1347 Score = 133 bits (322), Expect = 2e-29 Identities = 125/469 (26%), Positives = 202/469 (43%), Gaps = 44/469 (9%) Query: 31 LNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGLFFLR-ATHGRVHSDAGVYWCEA 87 + C A G+P+P+ W + + D S+ G + + GR G Y C A Sbjct: 61 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 120 Query: 88 TNSYGTARSRNATLHVAV--LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145 N +GTA S L V+ L + L+P Q +G + L+C PP G P P ++W + Sbjct: 121 RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQ--EGAPLTLQCNPPPGLPSPVIFWMSS 178 Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIAR-NAAGT-RESAIATLKI---- 198 + D R+ G+L + D Y C AR + T ++ TLK+ Sbjct: 179 SMEPITQ-DKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTR 237 Query: 199 ---HIKPYLI----TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251 P + T +V + G + +C G P PD+ W + GG++P + K Sbjct: 238 GVAERTPSFMYPQGTASSQMVLR-GMDLLLECIASGVPTPDIAWYKK--GGDLPSDKAKF 294 Query: 252 LD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310 + + +LR+ NV D GEY C A N +G++ + + V P P ++ + G Sbjct: 295 ENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDG 354 Query: 311 RFTCTATGRPEPTMFWSVEGN-RTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369 R C A G P+PT+ W V G P +R+ T +F DT + SR Sbjct: 355 RLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIF--------RDT-QISSRAV 405 Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEP 427 C+ N G ++V D PP +++ P NQ + + + C +P P Sbjct: 406 YQCNTSNEHGYLLANAFVSVL---DVPPRMLS--PRNQLIRVILYNRTRLDCPFFGSPIP 460 Query: 428 IIAWYFEGE-ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 + W+ G+ + + +V +G+L +K + K D G YTCVA++ GK Sbjct: 461 TLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGK 509 Score = 114 bits (275), Expect = 1e-23 Identities = 86/284 (30%), Positives = 134/284 (47%), Gaps = 15/284 (5%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS---DTHRSILPAGGLF 67 APY +++P ++ +A + L CRA G+P P ++W G + S + +R + AG Sbjct: 336 APYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREV--AGDTI 393 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTV 125 R T S VY C +N +G + NA + V + L P ++ + + Sbjct: 394 IFRDTQ---ISSRAVYQCNTSNEHGYLLA-NAFVSVLDVPPRM-LSPRNQLIRVILYNRT 448 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 L+C P GSP P + W KNGQ DG H+ + G+L I+ R+ D G Y C+A N Sbjct: 449 RLDC-PFFGSPIPTLRWFKNGQGSNLDG-GNYHVYENGSLEIKMIRKEDQGIYTCVATNI 506 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 G E+ + L++ + PED VA+ G++V +CRV DP + + Sbjct: 507 LGKAENQV-RLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLY 565 Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 +G +D SL + V D+G Y+C A + A YLTV Sbjct: 566 IGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 609 Score = 113 bits (272), Expect = 3e-23 Identities = 159/620 (25%), Positives = 249/620 (40%), Gaps = 65/620 (10%) Query: 10 EAPYIIEQPLD-VTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHR-SILPAGGL 66 ++P ++ LD V V P TL C G PSP I W + ++ R S G L Sbjct: 138 KSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDL 197 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYG-TARSRNA-TLHVAVLREEFR-----LEPESKQS 119 +F + +D Y C A + T + +N TL V R + P+ S Sbjct: 198 YFSNVMLQDMQTD---YSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTAS 254 Query: 120 AQ----GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175 +Q G ++LEC+ G P P++ W K G L D + L I + + D+ Sbjct: 255 SQMVLRGMDLLLECIAS-GVPTPDIAWYKKGGDLPSDKAKFENFNKA--LRITNVSEEDS 311 Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235 G Y C+A N G+ I+ +++ PY + P++++ G CR G+P P V W Sbjct: 312 GEYFCLASNKMGSIRHTIS-VRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQW 370 Query: 236 RRSAGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293 + P +V D + D I + Y C N G + A+ +++V D P Sbjct: 371 MVNGEPLQSAPPNPNREVAGDTIIFRDTQI-SSRAVYQCNTSNEHGYLLANAFVSVLDVP 429 Query: 294 SINLSPNS--VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 LSP + + V N R C G P PT+ W G + + G YH V++ Sbjct: 430 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGG----NYH---VYE 482 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411 + L I K D + C A N G + + +L V + P I P +Q Sbjct: 483 NGS-LEIKMIRKED-QGIYTCVATNILGKAENQVRLEV-----KDPTRIYRMPEDQVARR 535 Query: 412 KSMAVFPCTAICTP--EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469 + C P + ++W + E L +R +D +L + + + D G+YTCVA Sbjct: 536 GTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDD-SLTIFGVAERDQGSYTCVA 594 Query: 470 SSRHGKYVWSGAL--LVDSPINPNIHFFRAADVSSLP-GPPTKPITHNVTD---TSVTLS 523 S+ + + L L D N +++LP G P +P +TD SV L+ Sbjct: 595 STELDQDLAKAYLTVLADQATPTN-------RLAALPKGRPDRPRDLELTDLAERSVRLT 647 Query: 524 WSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITY 583 W + +S I Y V+ + G W ++ + V L P + Y Sbjct: 648 WIPGD-ANNSPITDYVVQFEEDQFQPG--------VWHDHSKYPGSVNSAVLRLSPYVNY 698 Query: 584 MFIVRTENSHGLSGPSPVSD 603 F V N G S PS S+ Sbjct: 699 QFRVIAINEVGSSHPSLPSE 718 Score = 88.2 bits (209), Expect = 1e-15 Identities = 103/395 (26%), Positives = 157/395 (39%), Gaps = 44/395 (11%) Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR-----QTDAGR 177 D +++EC +G+P P+ +W +N + D R+ + ++ D R + G Sbjct: 57 DNILIEC-EAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGE 115 Query: 178 YQCIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVLW 235 YQC ARN GT S L++ P + + VV Q G+ +T QC G P P + W Sbjct: 116 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFW 175 Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILAD-EGEYSCEAE-NSVGAVSASGYLTV---- 289 S+ RV +G L NV+L D + +YSC A + + T+ Sbjct: 176 MSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLT 235 Query: 290 -----YDPPSINL---SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341 PS + +S V G C A+G P P + W +G + Sbjct: 236 TRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGG------DLPS 289 Query: 342 DKYHATAVFDGVT-VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII 400 DK A F+ L I + + DS C A N GS +R ++V + P Sbjct: 290 DK----AKFENFNKALRITNVSEEDS-GEYFCLASNKMGS--IRHTISVRV---KAAPYW 339 Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ---NHRRNVTNDGTLVLKDL 457 + P N L C A P+P + W GE L N R V D T++ +D Sbjct: 340 LDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD-TIIFRDT 398 Query: 458 DKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492 S Y C S+ HG Y+ + A + + P + Sbjct: 399 QISSRAVYQCNTSNEHG-YLLANAFVSVLDVPPRM 432 Score = 62.9 bits (146), Expect = 5e-08 Identities = 70/279 (25%), Positives = 111/279 (39%), Gaps = 17/279 (6%) Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLD-DGSLRLD----NV 262 +D + ++ +C G+P P W R++ N+ RV + G+L +D Sbjct: 49 KDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGR 108 Query: 263 ILADEGEYSCEAENSVG-AVSASGYLTVYDPP---SINLSPNSVNVESGNVARFTCTAT- 317 EGEY C A N G A+S L V P NL P V V+ G C Sbjct: 109 PEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDP--VVVQEGAPLTLQCNPPP 166 Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377 G P P +FW I ++ F V +L TD + + + Sbjct: 167 GLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNV-MLQDMQTDYSCNARFHFTHTIQQ 225 Query: 378 AGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIKSM-AVFPCTAICTPEPIIAWYFEG 435 + F LT +R P + G ++ + ++ M + C A P P IAWY +G Sbjct: 226 K-NPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKG 284 Query: 436 EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 L + + + L + ++ + DSG Y C+AS++ G Sbjct: 285 GDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMG 323 >UniRef50_Q4SR22 Cluster: Chromosome 11 SCAF14528, whole genome shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 11 SCAF14528, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1154 Score = 133 bits (321), Expect = 3e-29 Identities = 89/298 (29%), Positives = 139/298 (46%), Gaps = 10/298 (3%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 + + + + L C A G P+P + W K G + T +I G L F+ D Sbjct: 226 EARLVKGEDLNLECIAAGFPTPQVEWVKMGQRL--PTKATIESHGKLLFVPTVE---QED 280 Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139 G Y C+A N+ G A T+ V E+ EPES+ S G V+++C G+P+P Sbjct: 281 GGKYMCKAKNTLGEA-VHYFTVTVEG-PPEWVSEPESQLSMIGSDVLIKC-SVSGTPQPT 337 Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199 V W+ NG L D + V G +V+ + + +D+ YQC A N GT S + ++ Sbjct: 338 VTWRVNGNRLQ-DSPAPNRRVLGDTIVLHNTKPSDSAVYQCEASNRHGTLLSNANIMIMN 396 Query: 200 IKPYLIT-GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLR 258 P ++T ED A G V C+V P P + W + ++ R V D+G+L Sbjct: 397 FPPMILTENDEDYSAVEGKRVMMHCKVFSSPSPTITWSKDDTSDSVDGPRFSVHDNGTLE 456 Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316 + D G Y+C A+N+ G+ + + L+V DP I P + G A+F+C A Sbjct: 457 IYRAEKEDAGPYTCFAKNTEGSSAINAMLSVKDPTRIVEPPEDSRILKGTTAQFSCLA 514 Score = 130 bits (313), Expect = 3e-28 Identities = 123/481 (25%), Positives = 194/481 (40%), Gaps = 40/481 (8%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTH-RSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89 + C A G+P P RW K G R I F+ +G + G+Y C A+N Sbjct: 26 MKCEAKGNPEPQFRWTKNGQQFDPFLDPRLIKEEDSGTFVIPNNGNLTEYQGIYRCFASN 85 Query: 90 SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149 GTA SR V + + + + +G VL+C PP G P +YW Sbjct: 86 VLGTAISREIEFIVPNVPKFPKETIDPVVVEEGQPFVLKCNPPDGIPPLQIYWMTISLQH 145 Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIA----------RNAAG----TRESA-- 192 + + D R+ G+L A D+ R Y C A + A T++ A Sbjct: 146 I-EQDERVSTSLNGDLYFSHAVDKDSRRDYCCFAAFPRIRTIVQKTAMSVIVKTKKDASP 204 Query: 193 -IATLKIHIKPYLITGP---EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248 +A + +P ++T P + G + +C G P P V W + G +P + Sbjct: 205 EVANAILQRRPSIMTPPGGKSEARLVKGEDLNLECIAAGFPTPQVEWVKM--GQRLPT-K 261 Query: 249 VKVLDDGSLR-LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESG 307 + G L + V D G+Y C+A+N++G +TV PP P S G Sbjct: 262 ATIESHGKLLFVPTVEQEDGGKYMCKAKNTLGEAVHYFTVTVEGPPEWVSEPESQLSMIG 321 Query: 308 NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367 + C+ +G P+PT+ W V GNR P +R T V +++T +DS Sbjct: 322 SDVLIKCSVSGTPQPTVTWRVNGNRLQDSPAPNRRVLGDTIV--------LHNTKPSDSA 373 Query: 368 NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427 C A N G+ + + + PP I+T + + + C +P P Sbjct: 374 -VYQCEASNRHGTLLSNANIMIM---NFPPMILTENDEDYSAVEGKRVMMHCKVFSSPSP 429 Query: 428 IIAWYFEGEA-LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486 I W + + + R +V ++GTL + +K D+G YTC A + G + L V Sbjct: 430 TITWSKDDTSDSVDGPRFSVHDNGTLEIYRAEKEDAGPYTCFAKNTEGSSAINAMLSVKD 489 Query: 487 P 487 P Sbjct: 490 P 490 Score = 113 bits (272), Expect = 3e-23 Identities = 108/425 (25%), Positives = 176/425 (41%), Gaps = 41/425 (9%) Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180 +G+ + LEC+ G P P V W K GQ L H G L + Q D G+Y C Sbjct: 231 KGEDLNLECIAA-GFPTPQVEWVKMGQRLPTKATIESH---GKLLFVPTVEQEDGGKYMC 286 Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 A+N G T+ + P ++ PE ++ GS V +C V G P P V WR + Sbjct: 287 KAKNTLGEAVHYF-TVTVEGPPEWVSEPESQLSMIGSDVLIKCSVSGTPQPTVTWRVNGN 345 Query: 241 G-GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299 + P +VL D ++ L N +D Y CEA N G + ++ + + + P + L+ Sbjct: 346 RLQDSPAPNRRVLGD-TIVLHNTKPSDSAVYQCEASNRHGTLLSNANIMIMNFPPMILTE 404 Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 N + + G C P PT+ WS + + ++ +V D T L Sbjct: 405 NDEDYSAVEGKRVMMHCKVFSSPSPTITWSKDDTSDSV----DGPRF---SVHDNGT-LE 456 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417 I +K D+ C A N GSS + L+V + P I P + + + A F Sbjct: 457 IYRAEKEDA-GPYTCFAKNTEGSSAINAMLSV-----KDPTRIVEPPEDSRILKGTTAQF 510 Query: 418 PCTA----ICTPEPIIAWYFEGEALIQNHRRN---VTNDGTLVLKDLDKSDSGTYTCVA- 469 C A + + I W + + + N+ N DG L + ++ D G YTC+A Sbjct: 511 SCLAEYDKSFSNDFEILWEKDDKEIAVNYTENSRYFVEDGLLQIVNVSHLDKGVYTCLAR 570 Query: 470 SSRHGKYVWSGALLVDSPINPNI-----HFFRAADVSSLPGPPTKPITHNVTDTSVTLSW 524 + G + L++D P P H ++ + +PG HN + T + + Sbjct: 571 TPMDGDKATALLLVIDVPDAPQYLVLSEHKSKSVKLKWIPGD-----DHNSSTTEFIIEY 625 Query: 525 SQNNK 529 ++ + Sbjct: 626 EESQR 630 Score = 97.9 bits (233), Expect = 1e-18 Identities = 79/271 (29%), Positives = 116/271 (42%), Gaps = 16/271 (5%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 + C G+P P + W G + + G L H SD+ VY CEA+N Sbjct: 326 IKCSVSGTPQPTVTWRVNGNRLQDSPAPNRRVLGDTIVL---HNTKPSDSAVYQCEASNR 382 Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLECLPPRGSPEPNVYWKKNGQTL 149 +GT S NA + + E + SA +G V++ C SP P + W K+ + Sbjct: 383 HGTLLS-NANIMIMNFPPMILTENDEDYSAVEGKRVMMHC-KVFSSPSPTITWSKDDTSD 440 Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI-ATLKIHIKPYLITGP 208 DG R + D G L I A + DAG Y C A+N G+ SAI A L + ++ P Sbjct: 441 SVDGP-RFSVHDNGTLEIYRAEKEDAGPYTCFAKNTEGS--SAINAMLSVKDPTRIVEPP 497 Query: 209 EDVVAQTGSSVTFQCRVGGDPLP----DVLWRRSAG--GGNMPLGRVKVLDDGSLRLDNV 262 ED G++ F C D ++LW + N ++DG L++ NV Sbjct: 498 EDSRILKGTTAQFSCLAEYDKSFSNDFEILWEKDDKEIAVNYTENSRYFVEDGLLQIVNV 557 Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPP 293 D+G Y+C A + A+ L V D P Sbjct: 558 SHLDKGVYTCLARTPMDGDKATALLLVIDVP 588 Score = 54.4 bits (125), Expect = 2e-05 Identities = 49/177 (27%), Positives = 77/177 (43%), Gaps = 15/177 (8%) Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFFLRAT 72 + E D + + ++C+ SPSP I W K D R S+ G L RA Sbjct: 402 LTENDEDYSAVEGKRVMMHCKVFSSPSPTITWSKDDTSDSVDGPRFSVHDNGTLEIYRAE 461 Query: 73 HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL--EPESKQSAQGDTVVLECL 130 DAG Y C A N+ G++ + NA L V ++ R+ PE + +G T CL Sbjct: 462 ----KEDAGPYTCFAKNTEGSS-AINAMLSV---KDPTRIVEPPEDSRILKGTTAQFSCL 513 Query: 131 PPRGSPEPN---VYWKKNGQTLLFD-GDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183 N + W+K+ + + + ++ + V+ G L I + D G Y C+AR Sbjct: 514 AEYDKSFSNDFEILWEKDDKEIAVNYTENSRYFVEDGLLQIVNVSHLDKGVYTCLAR 570 >UniRef50_UPI0000DB7802 Cluster: PREDICTED: similar to Neogenin precursor; n=1; Apis mellifera|Rep: PREDICTED: similar to Neogenin precursor - Apis mellifera Length = 1492 Score = 132 bits (320), Expect = 4e-29 Identities = 98/334 (29%), Positives = 139/334 (41%), Gaps = 16/334 (4%) Query: 13 YIIEQPLDVTVARHQPATLNCRAGGS-PSPAIRWYKGG---VLVVSDTHRSILPAGGLFF 68 Y +P DV V + PA L+C A S P I+W + + D++RS L G L+ Sbjct: 26 YFTIEPQDVVVEQGNPARLDCEANSSFGKPNIQWRTDDGQPINFIGDSYRSQLSNGSLY- 84 Query: 69 LRATHGRVHSDAGVYWCEAT-NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127 + + +G G Y C A+ + G SR AT+ +A L F EP+ G L Sbjct: 85 INSVYGTSLELTGSYQCLASVDDIGAIVSRIATIKIASL-PGFEKEPQDTMVYPGQIAYL 143 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 C S + W K+ L+ DSRM ++ G L I + + D G Y+C A + Sbjct: 144 SCTLLATSSSLIIQWLKDEHPLIISMDSRMTILPSGALEIDNVKTEDVGSYRCNASSYGQ 203 Query: 188 TRESAIATLKI-------HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 R S A L + P I P V GS++T +C G P P +LW + Sbjct: 204 YRLSNKAQLGLLSDIDQESTPPVFIAKPLQQVIIEGSTITLECAANGYPKPSILWLKDGV 263 Query: 241 GGNMPL--GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298 ++ R + SL + NV D G Y C AEN V + A+ L V PP Sbjct: 264 AIDLTSFKSRYSRIAASSLVISNVEEIDNGSYQCRAENEVEILDATADLIVQVPPRFIKK 323 Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332 P F C G+P+P + W G R Sbjct: 324 PEDKIASENQDLEFECEIYGKPQPKITWLKNGER 357 Score = 103 bits (248), Expect = 2e-20 Identities = 99/394 (25%), Positives = 157/394 (39%), Gaps = 29/394 (7%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN-GQTLLFDGDSRMHLVDGGNLVIQ 168 F +EP+ QG+ L+C +PN+ W+ + GQ + F GDS + G+L I Sbjct: 27 FTIEPQDVVVEQGNPARLDCEANSSFGKPNIQWRTDDGQPINFIGDSYRSQLSNGSLYIN 86 Query: 169 DARQTD---AGRYQCIAR-NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR 224 T G YQC+A + G S IAT+KI P P+D + G C Sbjct: 87 SVYGTSLELTGSYQCLASVDDIGAIVSRIATIKIASLPGFEKEPQDTMVYPGQIAYLSCT 146 Query: 225 VGGDPLPDVL-WRRSAGGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVS 282 + ++ W + + + R+ +L G+L +DNV D G Y C A +S G Sbjct: 147 LLATSSSLIIQWLKDEHPLIISMDSRMTILPSGALEIDNVKTEDVGSYRCNA-SSYGQYR 205 Query: 283 AS-----GYLTVYD----PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRT 333 S G L+ D PP P + G+ C A G P+P++ W +G Sbjct: 206 LSNKAQLGLLSDIDQESTPPVFIAKPLQQVIIEGSTITLECAANGYPKPSILWLKDGVAI 265 Query: 334 IIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393 + SR Y A + L I++ ++ D+ + C A N L V Sbjct: 266 DLTSFKSR--YSRIAA----SSLVISNVEEIDN-GSYQCRAENEVEILDATADLIV---- 314 Query: 394 DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLV 453 + PP P ++ F C P+P I W GE + + + N L Sbjct: 315 -QVPPRFIKKPEDKIASENQDLEFECEIYGKPQPKITWLKNGERITLSAYWQIVNGYNLR 373 Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 + L D+G + C+ ++ G + L ++ P Sbjct: 374 INGLLPIDAGIFQCIGTNSAGTVQAAARLTINQP 407 Score = 81.4 bits (192), Expect = 1e-13 Identities = 56/182 (30%), Positives = 83/182 (45%), Gaps = 8/182 (4%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I +PL + TL C A G P P+I W K GV + + +S L Sbjct: 225 PVFIAKPLQQVIIEGSTITLECAANGYPKPSILWLKDGVAIDLTSFKSRYSRIAASSLVI 284 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAV-LREEFRLEPESKQSAQGDTVVLECL 130 ++ D G Y C A N +AT + V + F +PE K +++ + EC Sbjct: 285 SNVE-EIDNGSYQCRAENE---VEILDATADLIVQVPPRFIKKPEDKIASENQDLEFEC- 339 Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190 G P+P + W KNG+ + + +V+G NL I DAG +QCI N+AGT + Sbjct: 340 EIYGKPQPKITWLKNGERITL--SAYWQIVNGYNLRINGLLPIDAGIFQCIGTNSAGTVQ 397 Query: 191 SA 192 +A Sbjct: 398 AA 399 Score = 62.9 bits (146), Expect = 5e-08 Identities = 43/168 (25%), Positives = 76/168 (45%), Gaps = 5/168 (2%) Query: 693 EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKW 752 ++ L YT+Y + + G S V +T P PP N+ + ++ T++ ++W Sbjct: 637 DLIDLVPYTEYSIKVQAVNENGPGVFSRDIVVRTYSAQPTQPPHNVTVEPVSPTSIMIRW 696 Query: 753 SPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAA 812 PP L+ QNGIITGY + D + +A T S ++T L V Y V+I A Sbjct: 697 EPP-LEGQNGIITGYKIRYRRHDRASPPVNIA---TEGNQRSRVLTGLEKHVVYQVRICA 752 Query: 813 ETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETW 860 + G GP+++ + + + P N +++ D++ W Sbjct: 753 LNVNGTGPWTEWIQIETYETESDENRVPNTPSNLRTKVMS-DYIQVFW 799 Score = 46.0 bits (104), Expect = 0.006 Identities = 38/131 (29%), Positives = 58/131 (44%), Gaps = 5/131 (3%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNT--TTVHLK 751 I L+ T YEF + K E S QT + P P N+ + + T+V L+ Sbjct: 944 INDLKPNTLYEFTVKLVKGKRESLWSMVVSNQTQEAAPSSAPRNLTIQSIEDRPTSVLLR 1003 Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811 W PP+ NG ITGY + + + ++ + I + T I+ L ++Y +I Sbjct: 1004 WQPPKQP--NGPITGYIIFYSIDNTKWDRDWL-IEGVIGDKTEFIVKGLQPSMTYYFKIQ 1060 Query: 812 AETIIGLGPFS 822 A G GPFS Sbjct: 1061 ARNSKGYGPFS 1071 >UniRef50_Q4TAD5 Cluster: Chromosome undetermined SCAF7373, whole genome shotgun sequence; n=28; Euteleostei|Rep: Chromosome undetermined SCAF7373, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1090 Score = 132 bits (320), Expect = 4e-29 Identities = 132/546 (24%), Positives = 222/546 (40%), Gaps = 40/546 (7%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 +T E P ++ P + R + A+L+C GSP + W K L+ I+ AG Sbjct: 286 LTVQEPPSFVKTPSPLEGIRGKDASLHCEVAGSPPFQVTWSKEQKLLKDSRKYKIIKAGS 345 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDT 124 L V DAGVY C+ +N+ GT +R A +++ ++ QS G+ Sbjct: 346 SVTLHIIKLEV-DDAGVYECQVSNNVGTESTRTA---ISLKEPPAFVKKLMDQSVMVGEQ 401 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIA 182 + L +GS ++ W ++ +L DGD+R + +L++ A AG+Y C Sbjct: 402 LTLTA-TVKGSEPLDISWIQDNDHVLRDGDNRTITFEKSVVSLIVPQADSATAGKYTCRL 460 Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRS 238 N +G S + + + ++ PE + QTG +V + + G W R Sbjct: 461 SNQSGVALS-VCHVTLLEPAAIVDSPESLNIQTGEAVALEVTICGSAELKTRWFKGDREL 519 Query: 239 AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSI 295 + G + K + +L++ + AD GEY E N VG S + L V D PPS Sbjct: 520 SAGNKYQMSSTKKV--ATLKIQSADKADAGEYKLEVSNHVGVASCTVTLAVSDKLIPPSF 577 Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355 ++ G C G T W +G I G+S D + D + Sbjct: 578 IRKLRDSHLVVGKSGDLDCKVIGSAPLTASWFHDGKE--IKSGLSYD----ISYVDNICK 631 Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415 L + D C A N AG+S + V PP + + ++LP +++ Sbjct: 632 LRLQTVQTTDG-GRYTCKAANAAGTSETSASVNVA----EPPSFVETPEAQESLPGNNVS 686 Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRR---NVTND-GTLVLKDLDKSDSGTYTCVASS 471 C + P+ +F G + + R ++ +D TLVL ++ +G YTC + Sbjct: 687 F--CAKVRGSSPLKVKWFRGSREMLHGRGCHISLKDDVATLVLNKVEMHHAGEYTCQVLN 744 Query: 472 RHGKYVWSGALLVDSPINPNIHFF-RAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530 GK + L V P +HF + D+S G P + V ++W ++ + Sbjct: 745 PVGKKSYPVYLSVREP----VHFVKKLRDISCEKGKPLRLEVSFAGTPRVNVTWKKDGGL 800 Query: 531 GSSSIL 536 +S L Sbjct: 801 IWASYL 806 Score = 107 bits (257), Expect = 2e-21 Identities = 116/485 (23%), Positives = 188/485 (38%), Gaps = 27/485 (5%) Query: 13 YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRAT 72 ++ + P V ++ +L CR S S I WYK + + ++ G L Sbjct: 200 FVQKLPPTTFVKLNEGHSLECRVSSSQSLNICWYKNDHKITDGANTKLM-FGDLSARLQL 258 Query: 73 HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP 132 D+G+Y CE N G+A S ++ L V F P + +G L C Sbjct: 259 LSAAFEDSGIYTCEVHNDAGSA-SCSSVLTVQE-PPSFVKTPSPLEGIRGKDASLHC-EV 315 Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT--DAGRYQCIARNAAGTRE 190 GSP V W K Q LL D + G ++ + + DAG Y+C N GT E Sbjct: 316 AGSPPFQVTWSKE-QKLLKDSRKYKIIKAGSSVTLHIIKLEVDDAGVYECQVSNNVGT-E 373 Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS-----AGGGNMP 245 S + + P + D G +T V G D+ W + G N Sbjct: 374 STRTAISLKEPPAFVKKLMDQSVMVGEQLTLTATVKGSEPLDISWIQDNDHVLRDGDNRT 433 Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305 + K + SL + A G+Y+C N G + ++T+ +P +I SP S+N++ Sbjct: 434 ITFEKSVV--SLIVPQADSATAGKYTCRLSNQSGVALSVCHVTLLEPAAIVDSPESLNIQ 491 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365 +G T G E W +G+R + + +KY ++ V L I DK D Sbjct: 492 TGEAVALEVTICGSAELKTRW-FKGDREL----SAGNKYQMSST-KKVATLKIQSADKAD 545 Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425 + N+ G + +T+ D PP + L + C I + Sbjct: 546 A-GEYKLEVSNHVGVASC--TVTLAVSDKLIPPSFIRKLRDSHLVVGKSGDLDCKVIGSA 602 Query: 426 EPIIAWYFEGEAL---IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482 +W+ +G+ + + V N L L+ + +D G YTC A++ G S ++ Sbjct: 603 PLTASWFHDGKEIKSGLSYDISYVDNICKLRLQTVQTTDGGRYTCKAANAAGTSETSASV 662 Query: 483 LVDSP 487 V P Sbjct: 663 NVAEP 667 Score = 103 bits (247), Expect = 3e-20 Identities = 114/482 (23%), Positives = 193/482 (40%), Gaps = 24/482 (4%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64 +VT E I++ P + + + L GS RW+KG + + + Sbjct: 472 HVTLLEPAAIVDSPESLNIQTGEAVALEVTICGSAELKTRWFKGDRELSAGNKYQMSSTK 531 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQG 122 + L+ +DAG Y E +N G A S TL V+ ++ F + G Sbjct: 532 KVATLKIQSAD-KADAGEYKLEVSNHVGVA-SCTVTLAVSDKLIPPSFIRKLRDSHLVVG 589 Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCI 181 + L+C GS W +G+ + + VD L +Q + TD GRY C Sbjct: 590 KSGDLDC-KVIGSAPLTASWFHDGKEIKSGLSYDISYVDNICKLRLQTVQTTDGGRYTCK 648 Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241 A NAAGT E++ A++ + P + PE + G++V+F +V G V W R G Sbjct: 649 AANAAGTSETS-ASVNVAEPPSFVETPEAQESLPGNNVSFCAKVRGSSPLKVKWFR--GS 705 Query: 242 GNMPLGR---VKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297 M GR + + DD +L L+ V + GEY+C+ N VG S YL+V +P Sbjct: 706 REMLHGRGCHISLKDDVATLVLNKVEMHHAGEYTCQVLNPVGKKSYPVYLSVREPVHFVK 765 Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 ++ E G R + G P + W +G +I+ + D +L Sbjct: 766 KLRDISCEKGKPLRLEVSFAGTPRVNVTWKKDGG--LIWASY----LYNVITTDTSCILE 819 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417 + ++D+ ++ T C N G+ +++ P + S + S+ + Sbjct: 820 VLNSDRMEAAGTYSCHLDNGVGNDVCEAHVSIL----ERPSFVERMESVEINEGDSL-LL 874 Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477 C TPE ++W+ ++ T L+ L VA ++ GK + Sbjct: 875 RCLIEGTPEISVSWFKAEPVHFTRKLKDTTFTLGQPLQLLCTYSGSPRVSVAWTKDGKPI 934 Query: 478 WS 479 W+ Sbjct: 935 WA 936 Score = 66.9 bits (156), Expect = 3e-09 Identities = 86/386 (22%), Positives = 146/386 (37%), Gaps = 37/386 (9%) Query: 127 LECLPPRGSPEP-NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR----QTDAGRYQCI 181 L CL P P NV W +NG+ + + + Q +R Y C Sbjct: 122 LVCLVTGFYPAPVNVSWTRNGEEVTQGTSINVPYPNNEGTFTQISRLDFVPQQGDIYSCR 181 Query: 182 ARNAAGTRESAIATLKIHIKPYLITG-PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 ++ A + A ++ P + P + + +CRV ++ W ++ Sbjct: 182 VQHPALSE----ADTRMWKPPQFVQKLPPTTFVKLNEGHSLECRVSSSQSLNICWYKNDH 237 Query: 241 GGNMPLGRVKVLDDGSLRLDNVILA--DEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298 + D S RL + A D G Y+CE N G+ S S LTV +PPS + Sbjct: 238 KITDGANTKLMFGDLSARLQLLSAAFEDSGIYTCEVHNDAGSASCSSVLTVQEPPSFVKT 297 Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358 P+ + G A C G P + WS E KY VT+ I Sbjct: 298 PSPLEGIRGKDASLHCEVAGSPPFQVTWSKEQKLL-----KDSRKYKIIKAGSSVTLHII 352 Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418 + D C N G+ R +++ + PP +Q++ + Sbjct: 353 K--LEVDDAGVYECQVSNNVGTESTRTAISL-----KEPPAFVKKLMDQSVMVGEQLTLT 405 Query: 419 CTAICTPEPI-IAWYFEGEALIQN-HRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRH 473 T + EP+ I+W + + ++++ R +T + +L++ D + +G YTC S++ Sbjct: 406 AT-VKGSEPLDISWIQDNDHVLRDGDNRTITFEKSVVSLIVPQADSATAGKYTCRLSNQS 464 Query: 474 G-------KYVWSGALLVDSPINPNI 492 G + A +VDSP + NI Sbjct: 465 GVALSVCHVTLLEPAAIVDSPESLNI 490 Score = 56.4 bits (130), Expect = 4e-06 Identities = 43/173 (24%), Positives = 74/173 (42%), Gaps = 13/173 (7%) Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 G + CT +G P ++ W+ +G P + +Y+ + VL I ++D+ + Sbjct: 908 GQPLQLLCTYSGSPRVSVAWTKDGK-----PIWASYQYNVRTT-NSSCVLEILNSDRPAA 961 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426 T C+ N AGS ++++ + + P T P + + V + + Sbjct: 962 GGTYACAISNGAGSDKCHARVSL---EHKTAPSFTRRPPESLVDSEGKTVKIEARVSGSQ 1018 Query: 427 PI-IAWYFEGEALIQNHRRN---VTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 P+ + WY + + H V N L LK+ KS SG YTC AS+ GK Sbjct: 1019 PLNVTWYKDNNEICSCHNYEMSFVNNLAILCLKNSSKSQSGVYTCSASNEAGK 1071 Score = 46.4 bits (105), Expect = 0.005 Identities = 41/164 (25%), Positives = 65/164 (39%), Gaps = 10/164 (6%) Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNL--VIQDARQTDAGRYQCIARNAAGTRES 191 GSP +V W K+G+ + + + + ++ R G Y C N AG+ + Sbjct: 919 GSPRVSVAWTKDGKPIWASYQYNVRTTNSSCVLEILNSDRPAAGGTYACAISNGAGSDKC 978 Query: 192 -AIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGGGNMP 245 A +L+ P + PE +V G +V + RV G +V W + N Sbjct: 979 HARVSLEHKTAPSFTRRPPESLVDSEGKTVKIEARVSGSQPLNVTWYKDNNEICSCHNYE 1038 Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 + V L L L N + G Y+C A N G S +T+ Sbjct: 1039 MSFVNNL--AILCLKNSSKSQSGVYTCSASNEAGKASCLVSVTI 1080 >UniRef50_Q7QEI6 Cluster: ENSANGP00000020451; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000020451 - Anopheles gambiae str. PEST Length = 1228 Score = 132 bits (319), Expect = 6e-29 Identities = 133/508 (26%), Positives = 196/508 (38%), Gaps = 54/508 (10%) Query: 12 PYIIEQPLDVT-----VARHQPATLNCRAGGSPSPAIRWYK-----GGVLVVS----DTH 57 PY I QP+D T + + TL+C AGG P+P WYK + V+ Sbjct: 214 PYFIRQPVDTTYDTGKASITRDVTLSCLAGGYPTPRYTWYKEEYVKDNLTVIQIDPLRNA 273 Query: 58 RSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK 117 R + G L R + + D G Y C A N+YG S + L+ + E F L+ + Sbjct: 274 RHTVSGGNLIIHRPSQ---NLDQGTYHCTAQNAYGKILSESVQLNFGYILE-FNLQRAPE 329 Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR 177 + + L C P+ P+ YW +N D R+ + G+L D Sbjct: 330 KGEENWGKALVCEEPQHYPDVKFYWSRNYFPNFVYEDQRVFVSHDGSLYFSSLEVMDRAN 389 Query: 178 YQCIARNAAGT--RESAIATLKIHIKPY---LI---TGPEDV--VAQTGSSVTFQCRVGG 227 Y C + R L + P+ LI T P+ V G V +C G Sbjct: 390 YSCTVMSTVSDTGRNGPFFELSVSPSPHYQDLIFANTFPKAFPKVPLAGKDVRLECMTYG 449 Query: 228 DPLPDVLWRRSAGGGNMPLGRVKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASG 285 P+ W R GN+P R+ L++ + L + N + D GEY C A N +++ S Sbjct: 450 YPVASYNWTRR--NGNLP--RLSRLENYNRVLLIQNATVNDNGEYVCTARNGKKSITQSI 505 Query: 286 YLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR----TIIFPG-MS 340 +L V P+ + + + F C A P+ W G + G ++ Sbjct: 506 FLNVQMEPNFTIPLRDRTKDFQSSVSFLCEAYAMPDVNYTWYKNGELMEEDSATGGGRLN 565 Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII 400 RDKY + D + L IN D + C A N + +L V S P Sbjct: 566 RDKY---TIQDNL--LKINYLDPEEDNGMYQCKATNQLKGVYSAAQLRVLS----MKPSF 616 Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPE----PIIAWYFEGEALIQNHRRNVTNDGTLVLKD 456 P I S+A T C PE P I W +G + R + GTL + Sbjct: 617 KKRPLESE--IYSIANGNTTIRCEPEAAPTPKIVWKKDGNVIGSGGHRKIYPTGTLHISP 674 Query: 457 LDKSDSGTYTCVASSRHGKYVWSGALLV 484 + D GTYTC+AS+ G L+V Sbjct: 675 TSRDDEGTYTCIASNTQGMAESKARLIV 702 Score = 83.4 bits (197), Expect = 3e-14 Identities = 81/330 (24%), Positives = 127/330 (38%), Gaps = 41/330 (12%) Query: 33 CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF----------FLRATHGRVHSDAGV 82 C A P WYK G L+ D+ GG L+ + D G+ Sbjct: 534 CEAYAMPDVNYTWYKNGELMEEDS----ATGGGRLNRDKYTIQDNLLKINYLDPEEDNGM 589 Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFR---LEPESKQSAQGDTVVLECLPPRGSPEPN 139 Y C+ATN S A L V ++ F+ LE E A G+T + C P +P P Sbjct: 590 YQCKATNQLKGVYSA-AQLRVLSMKPSFKKRPLESEIYSIANGNTTI-RC-EPEAAPTPK 646 Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199 + WKK+G + G +++ G L I + D G Y CIA N G ES + + Sbjct: 647 IVWKKDGNVIGSGGHRKIYPT--GTLHISPTSRDDEGTYTCIASNTQGMAESKARLIVLQ 704 Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV--LWR-----------------RSAG 240 + P + Q G + +C V D L DV +W R Sbjct: 705 ELRFTEQLPPKQIKQIGEMLFLRCDVTYDQLLDVAFVWTHNGQLLTGHDDADEQRLRQQP 764 Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300 G P G + +L + N+ L D GEY C A++SV + + + + PP + Sbjct: 765 IGPAPDGARIRIHYNTLEVHNLTLVDGGEYECVAKSSVNRIVSRATVLIQGPPGAPGAVK 824 Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEG 330 ++++ P +++++ G Sbjct: 825 VIDIKKTEALLEWTNGNDNGRPILYYNILG 854 Score = 38.3 bits (85), Expect = 1.3 Identities = 31/132 (23%), Positives = 58/132 (43%), Gaps = 7/132 (5%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753 I L T Y ++ + EG S + +T P PP +++++ +N +T+ + W Sbjct: 1091 IVGLEPDTYYFVKVMAYNAAGEGPESERYLERTYRKAPQKPPSSVQIYGINPSTIKVTWR 1150 Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTT---VHQATSLIMTNLTSGVSYSVQI 810 + GY + + W ++ M + N T V + + NLT G SY++++ Sbjct: 1151 YIAPSQDEEPVQGYKIRI-W---EKDQDMSSANDTVVLVGRKLEKYIDNLTPGKSYNLRV 1206 Query: 811 AAETIIGLGPFS 822 A + G G S Sbjct: 1207 LAFSNGGDGRMS 1218 >UniRef50_Q810U4 Cluster: Neuronal cell adhesion molecule precursor; n=48; Euteleostomi|Rep: Neuronal cell adhesion molecule precursor - Mus musculus (Mouse) Length = 1256 Score = 132 bits (319), Expect = 6e-29 Identities = 160/660 (24%), Positives = 260/660 (39%), Gaps = 63/660 (9%) Query: 117 KQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAG 176 K+ +G+ + LEC+ G P P +YW K L + + L I + D+G Sbjct: 274 KEELRGNVLSLECIA-EGLPTPIIYWIKEDGML--PANRTFYRNFKKTLQITHVSEADSG 330 Query: 177 RYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 YQCIA+NA G I+ + + PY I P+++V G + T CR G+P P + W Sbjct: 331 NYQCIAKNALGAVHHTIS-VTVKAAPYWIVAPQNLVLSPGENGTLICRANGNPKPRISWL 389 Query: 237 RSAGGGNMPLGRV-KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-DPPS 294 + + L + +D ++ NV + Y C A N G + A+ ++ V +PP Sbjct: 390 TNGVPIEIALDDPSRKIDGDTIIFSNVQESSSAVYQCNASNKYGYLLANAFVNVLAEPPR 449 Query: 295 INLSPNSV-NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353 I S N++ V + A C G P PT+ W +G + + D Y + D Sbjct: 450 ILTSANTLYQVIANRPALLDCAFFGSPMPTIEW-FKGTKG---SALHEDIY---VLHDNG 502 Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413 T L I K DS T C A N G + L + + P I P + S Sbjct: 503 T-LEIPVAQK-DSTGTYTCVARNKLGMAKNEVHLEI-----KDPTRIIKQPEYAVVQRGS 555 Query: 414 MAVFPCTAIC--TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471 F C T P I W + L N R T+ LV+ D+ D GTYTC A++ Sbjct: 556 KVSFECRVKHDHTLIPTIMWLKDNGEL-PNDERFSTDKDHLVVSDVKDDDGGTYTCTANT 614 Query: 472 RHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIG 531 S L V +P P A + +P PP N D SV L+W+ + Sbjct: 615 TLDSASASAVLRVVAP-TPT-----PAPIYDVPNPPFDLELTNQLDKSVQLTWTPGDD-N 667 Query: 532 SSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTEN 591 +S I + +E + ++ W A L P + Y F V EN Sbjct: 668 NSPITKFIIEY--------EDAMHDAGLWRHQAEVSGTQTTAQLKLSPYVNYSFRVMAEN 719 Query: 592 SHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKL 651 S G S PS S+ ++ + E N + +E + + + Sbjct: 720 SIGRSMPSEASEQY--------------LTKAAEPDQNPMA------VEGLGTEPDNLVI 759 Query: 652 MWEILNFYYLEGLFIYFR-PLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPF 710 W+ LN + G + ++ + E +++ +N VS + ++ + Y + Sbjct: 760 TWKPLNGFQSNGPGLQYKVSWRQKDGDDEWTSVVVAN-VSKYIVSGTPTFVPY-LIKVQA 817 Query: 711 YKKFEGKPSNSRV-AQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNV 769 P + V + +D+P P N+ + ++N+T + W P + G + GY + Sbjct: 818 LNDVGFAPEPAAVMGHSGEDLPMVAPGNVRVSVVNSTLAEVHWDPVPPKSVRGHLQGYRI 877 Score = 113 bits (273), Expect = 2e-23 Identities = 93/295 (31%), Positives = 132/295 (44%), Gaps = 21/295 (7%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSDTHRSILP 62 VT APY I P ++ ++ + TL CRA G+P P I W GV + + D R I Sbjct: 349 VTVKAAPYWIVAPQNLVLSPGENGTLICRANGNPKPRISWLTNGVPIEIALDDPSRKI-D 407 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK---QS 119 + F S + VY C A+N YG A V VL E R+ + Q Sbjct: 408 GDTIIFSNVQ----ESSSAVYQCNASNKYGYLL---ANAFVNVLAEPPRILTSANTLYQV 460 Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179 +L+C GSP P + W K + D + L D G L I A++ G Y Sbjct: 461 IANRPALLDC-AFFGSPMPTIEWFKGTKGSALHEDIYV-LHDNGTLEIPVAQKDSTGTYT 518 Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRR 237 C+ARN G ++ + L+I +I PE V Q GS V+F+CRV D +P ++W + Sbjct: 519 CVARNKLGMAKNEV-HLEIKDPTRIIKQPEYAVVQRGSKVSFECRVKHDHTLIPTIMWLK 577 Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292 G +P D L + +V D G Y+C A ++ + SAS L V P Sbjct: 578 D--NGELPNDERFSTDKDHLVVSDVKDDDGGTYTCTANTTLDSASASAVLRVVAP 630 Score = 107 bits (258), Expect = 1e-21 Identities = 182/813 (22%), Positives = 312/813 (38%), Gaps = 87/813 (10%) Query: 30 TLNCRAGGSPSPAIRWYK-GGVLVVSDT-HRSILPAGGLFFLRATHGRVHSDAGVYWCEA 87 +L C A G P+P I W K G+L + T +R+ L+ TH +D+G Y C A Sbjct: 283 SLECIAEGLPTPIIYWIKEDGMLPANRTFYRNFKKT-----LQITHVS-EADSGNYQCIA 336 Query: 88 TNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146 N+ G T+ V V + + P++ + G+ L C G+P+P + W NG Sbjct: 337 KNALGAVHH---TISVTVKAAPYWIVAPQNLVLSPGENGTLICRA-NGNPKPRISWLTNG 392 Query: 147 QTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT 206 + D +DG ++ + +++ + YQC A N G A A + + +P I Sbjct: 393 VPIEIALDDPSRKIDGDTIIFSNVQESSSAVYQCNASNKYGYL-LANAFVNVLAEPPRIL 451 Query: 207 GPEDVVAQTGSS--VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264 + + Q ++ C G P+P + W + G + + D+G+L + Sbjct: 452 TSANTLYQVIANRPALLDCAFFGSPMPTIEWFKGTKGSALHEDIYVLHDNGTLEIPVAQK 511 Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPE--P 322 G Y+C A N +G +L + DP I P V+ G+ F C P Sbjct: 512 DSTGTYTCVARNKLGMAKNEVHLEIKDPTRIIKQPEYAVVQRGSKVSFECRVKHDHTLIP 571 Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382 T+ W + S DK H L ++D K+D T C+A S+ Sbjct: 572 TIMWLKDNGELPNDERFSTDKDH----------LVVSDV-KDDDGGTYTCTANTTLDSAS 620 Query: 383 VRGKLTVTSDDDRPPPI--ITNGPSNQTLP---IKSMAVFPCTAICTPEPIIAWYFEGE- 436 L V + P PI + N P + L KS+ + PI + E E Sbjct: 621 ASAVLRVVAPTPTPAPIYDVPNPPFDLELTNQLDKSVQLTWTPGDDNNSPITKFIIEYED 680 Query: 437 ----ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492 A + H+ V+ T L + ++ +A + G+ + S A Sbjct: 681 AMHDAGLWRHQAEVSGTQTTAQLKLSPYVNYSFRVMAENSIGRSMPSEA--------SEQ 732 Query: 493 HFFRAADVSSLP----GPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETL 548 + +AA+ P G T+P ++ ++W N S+ G Q +V R+ Sbjct: 733 YLTKAAEPDQNPMAVEGLGTEP-------DNLVITWKPLNGFQSNG-PGLQYKVSWRQK- 783 Query: 549 SGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVG 608 G++ + VV+A + + Y+V + Y+ V+ N G + P P + G Sbjct: 784 DGDDEWTS----VVVA---NVSKYIVSGTPTFVPYLIKVQALNDVGFA-PEPAAVMGHSG 835 Query: 609 DDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYF 668 +D + G R +++ + E + P+ K+++ + YY + Sbjct: 836 EDLPMVAPG-------NVRVSVVNSTLAE-VHWDPVPPKSVRGHLQGYRIYYWKTQSSSK 887 Query: 669 RPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLD 728 R +I E K + + + L+ Y+ Y + K EG S R T + Sbjct: 888 RNRRHI----EKKILTFQGTKTHGMLPGLQPYSHYALNVRVVNGKGEGPASTDRGFHTPE 943 Query: 729 DVPDGPPINIEMFILNTT--TVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN 786 VP P + I+N T ++ L+W PP NGI+T Y + ++ + Sbjct: 944 GVPSAPS---SLKIVNPTLDSLTLEWDPP--SHPNGILTEYILQYQPINSTHELGPLVDL 998 Query: 787 TTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819 T + NL Y A+T +G G Sbjct: 999 KIPANKTRWTLKNLNFSTRYKFYFYAQTSVGPG 1031 Score = 64.1 bits (149), Expect = 2e-08 Identities = 51/181 (28%), Positives = 77/181 (42%), Gaps = 10/181 (5%) Query: 10 EAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGL 66 + P I +Q P D + + + C A G P P+ W + G + D ++ P G Sbjct: 38 QPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGSGT 97 Query: 67 FFLRA-THGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGD 123 + + G+ + GVY C A N G A S N + + L + RLEP Q+ G Sbjct: 98 LVINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKERLEPIVLQN--GQ 155 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIA 182 ++VL C PP G P ++W N L + R+ G+L + D Y C A Sbjct: 156 SLVLPCRPPIGLPPAIIFWMDNSFQRLPQSE-RVSQGLNGDLYFSNVLPEDTREDYICYA 214 Query: 183 R 183 R Sbjct: 215 R 215 Score = 52.4 bits (120), Expect = 7e-05 Identities = 47/160 (29%), Positives = 68/160 (42%), Gaps = 9/160 (5%) Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVI----QDARQTDAGR 177 + +V++C +G P P+ W +NG D D + + G G LVI + +T G Sbjct: 56 ENIVIQC-EAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGSGTLVINIMSEGKAETYEGV 114 Query: 178 YQCIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLW 235 YQC ARN G S ++ P + E +V Q G S+ CR G P + W Sbjct: 115 YQCTARNERGAAVSNNIVVRPSRSPLWTKERLEPIVLQNGQSLVLPCRPPIGLPPAIIFW 174 Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGE-YSCEA 274 ++ RV +G L NV+ D E Y C A Sbjct: 175 MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYA 214 >UniRef50_UPI00006607E8 Cluster: Homolog of Homo sapiens "OTTHUMP00000065309; n=2; Clupeocephala|Rep: Homolog of Homo sapiens "OTTHUMP00000065309 - Takifugu rubripes Length = 1211 Score = 132 bits (318), Expect = 7e-29 Identities = 129/484 (26%), Positives = 194/484 (40%), Gaps = 37/484 (7%) Query: 10 EAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGL 66 + P I++Q D V + C A G+ P W + G V D ++ G Sbjct: 9 QPPTIVKQSAKDYIVDPRDNIIIECEAKGNTLPTFSWRRNGKFFNVGKDPRVTMRKRSGT 68 Query: 67 FFLRATHG-RVHSDAGVYWCEATNSYGTARSRNATLHV--AVLREEFRLEPESKQSAQGD 123 + G R G Y C A N G A S L V A L + L+P +G Sbjct: 69 LEISFRRGGRPEDYEGEYQCFANNELGVALSNKILLRVSKAPLWPKEVLDPVLVN--EGS 126 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIA 182 ++L C PP G P P ++W N T + D R+ + G+L + DA Y+C A Sbjct: 127 PLILPCNPPPGLPPPLIFWMDNTMTPIVQ-DKRVSMGLNGDLYFSNVMTKDALNEYKCNA 185 Query: 183 RN--AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGG----DPLPDVLWR 236 R ++ LK+ L +++ GS + G DP P + W Sbjct: 186 RCRLTQTIQQKNPFILKVQTSRKLPQSMPTLLSPVGSQSSKMVLRGQELLLDPTPSIKWY 245 Query: 237 RSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295 R GG++P +VK + + +L + V D GEY C A N +G+V S + V P Sbjct: 246 RK--GGDLPERKVKFENFNKTLVVMGVSEEDAGEYVCMANNHLGSVRHSILVQVKAAPYW 303 Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF-PGMSRDKYHATAVFDGVT 354 P ++ + R C A G P+P + W + G P R T +F V Sbjct: 304 LDKPTNLVLAPDEHGRLVCRANGNPKPNIQWLINGQPIETSPPNPGRQVLGDTIIFRSVQ 363 Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--K 412 + S C+A N G ++V D PP ++ GP NQ + + Sbjct: 364 M---------GSSAVYQCNASNQYGYLLANAFISVL---DMPPRML--GPKNQLIKVIEN 409 Query: 413 SMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471 + C +P P + W+ G+ + V N+GTL +K D GTYTCVA++ Sbjct: 410 THTFLDCPFFGSPLPDLRWFKNGQGSGVDGGHYTVHNNGTLEIKRARAEDEGTYTCVANN 469 Query: 472 RHGK 475 GK Sbjct: 470 LLGK 473 Score = 112 bits (270), Expect = 5e-23 Identities = 89/284 (31%), Positives = 135/284 (47%), Gaps = 15/284 (5%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWY-KGGVLVVSDTHRSILPAGGLFFL 69 APY +++P ++ +A + L CRA G+P P I+W G + S + G Sbjct: 300 APYWLDKPTNLVLAPDEHGRLVCRANGNPKPNIQWLINGQPIETSPPNPGRQVLGDTIIF 359 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTVVL 127 R+ + VY C A+N YG + NA + V + L P+++ + + L Sbjct: 360 RSVQ---MGSSAVYQCNASNQYGYLLA-NAFISVLDMPPRM-LGPKNQLIKVIENTHTFL 414 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 +C P GSP P++ W KNGQ DG + + G L I+ AR D G Y C+A N G Sbjct: 415 DC-PFFGSPLPDLRWFKNGQGSGVDG-GHYTVHNNGTLEIKRARAEDEGTYTCVANNLLG 472 Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP-LP-DVLWRRSAGGGNMP 245 E+ + L++ +I P+ A GS+ F+C+V DP LP V W + N+ Sbjct: 473 KAENQVR-LEVKEATRIIGVPQHQSAVRGSTARFKCQVKSDPSLPVTVTWTKDDKPLNVG 531 Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 K D+ L + V DEG Y+C ++ + A SAS LTV Sbjct: 532 WRLRK--DEDLLSISAVNEGDEGMYTCTVKSEIDADSASARLTV 573 Score = 103 bits (246), Expect = 4e-20 Identities = 197/844 (23%), Positives = 310/844 (36%), Gaps = 87/844 (10%) Query: 10 EAPYIIEQPLD-VTVARHQPATLNCRAG-GSPSPAIRWYKGGVL-VVSDTHRSILPAGGL 66 +AP ++ LD V V P L C G P P I W + +V D S+ G L Sbjct: 108 KAPLWPKEVLDPVLVNEGSPLILPCNPPPGLPPPLIFWMDNTMTPIVQDKRVSMGLNGDL 167 Query: 67 FFLRATHGRVHSDA-GVYWCEAT-NSYGTARSRNA-TLHVAVLREEFRLEPE--SKQSAQ 121 +F + DA Y C A T + +N L V R+ + P S +Q Sbjct: 168 YFSNV----MTKDALNEYKCNARCRLTQTIQQKNPFILKVQTSRKLPQSMPTLLSPVGSQ 223 Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQ 179 +VL P P++ W + G L R + N LV+ + DAG Y Sbjct: 224 SSKMVLRGQELLLDPTPSIKWYRKGGDL----PERKVKFENFNKTLVVMGVSEEDAGEYV 279 Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239 C+A N G+ +I +++ PY + P ++V CR G+P P++ W + Sbjct: 280 CMANNHLGSVRHSIL-VQVKAAPYWLDKPTNLVLAPDEHGRLVCRANGNPKPNIQWLING 338 Query: 240 GG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297 + P +VL D ++ +V + Y C A N G + A+ +++V D P L Sbjct: 339 QPIETSPPNPGRQVLGD-TIIFRSVQMGSSAVYQCNASNQYGYLLANAFISVLDMPPRML 397 Query: 298 SPNS--VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355 P + + V C G P P + W G G D H T +G Sbjct: 398 GPKNQLIKVIENTHTFLDCPFFGSPLPDLRWFKNGQ------GSGVDGGHYTVHNNGT-- 449 Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415 L I D T C A N G + + +L V + I P +Q+ S A Sbjct: 450 LEIKRARAEDE-GTYTCVANNLLGKAENQVRLEV-----KEATRIIGVPQHQSAVRGSTA 503 Query: 416 VFPCTAICTPE-PI-IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473 F C P P+ + W + + L R D L + +++ D G YTC S Sbjct: 504 RFKCQVKSDPSLPVTVTWTKDDKPLNVGWRLRKDED-LLSISAVNEGDEGMYTCTVKSEI 562 Query: 474 GKYVWSGALLV--DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIG 531 S L V P+ I F + P PP + + SV L+W N+ Sbjct: 563 DADSASARLTVLGHEPVFDMISGF----YTGCPDPPVELDLSDPAARSVRLTWIPGNE-H 617 Query: 532 SSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTEN 591 S + + V+ G W ++ + V+ L P + Y F V N Sbjct: 618 RSPVTHFLVQFEEDRWEPGQ--------WRNMSSYPGHLNSVILQLAPFVNYQFRVIAIN 669 Query: 592 SHGLSGPS-PVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIK 650 S G S PS P T G + + G S + I + +++L + Sbjct: 670 SVGQSEPSTPSPQYKTSGAAPDVIPRGLRGWGSMKDNMEITWEPLLDLERNGA--NLIYS 727 Query: 651 LMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPF 710 L W + +N+T K ++HS + Y YE + Sbjct: 728 LWWRRKDM---------SEDWNNVTTAGN-KHMVHSTET----------YVPYEIKIQAG 767 Query: 711 YKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNV- 769 + G SN V + +D P P ++ + +++T ++ W P +L+ G Y + Sbjct: 768 NEFGSGPVSNVVVGYSGEDTPTTAPTDLRVSKVDSTKAYIHWKPVDLKSVQGEFKEYRLY 827 Query: 770 ------VVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQ 823 +V L+V K + +TV + +SL+ L + A T GP S Sbjct: 828 YWRDASLVPGLEVSKEKQIKGFYSTVSEPSSLLSELLPFSKYKMFMVVANTRYE-GPASN 886 Query: 824 KVYF 827 V F Sbjct: 887 TVEF 890 Score = 49.6 bits (113), Expect = 5e-04 Identities = 46/173 (26%), Positives = 80/173 (46%), Gaps = 11/173 (6%) Query: 597 GPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEIL 656 G PVS+ V VG E T + T+ R + + D I P+D K+++ ++ Sbjct: 771 GSGPVSN-VVVGYSG----EDTPTTAPTDLRVSKV-DSTKAYIHWKPVDLKSVQGEFKEY 824 Query: 657 NFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEG 716 YY + P ++ E ++K + ++ L ++KY+ F++ ++EG Sbjct: 825 RLYYWRDASLV--PGLEVSKEKQIKGFYSTVSEPSSLLSELLPFSKYKMFMVVANTRYEG 882 Query: 717 KPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNV 769 SN+ T + VPD P + + N T+ LKW P L+ NGI+ GY + Sbjct: 883 PASNTVEFTTKEGVPDIPRL-FTINWKNLDTIQLKWGKP-LE-PNGILIGYQL 932 >UniRef50_UPI000065FAD3 Cluster: Homolog of Brachydanio rerio "Neural adhesion molecule L1.2.; n=1; Takifugu rubripes|Rep: Homolog of Brachydanio rerio "Neural adhesion molecule L1.2. - Takifugu rubripes Length = 1204 Score = 131 bits (316), Expect = 1e-28 Identities = 134/485 (27%), Positives = 202/485 (41%), Gaps = 60/485 (12%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 + P + E P +T L C+A G+P P W K GVL+ S H L A L Sbjct: 4 QPPVLSEVPESITAFSPVDIHLPCKAKGNPPPTFHWMKDGVLIRSGLHLGTLKAEEEEPL 63 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 + G Y C A+N YGTA +++ + V + + K+S +G++++L C Sbjct: 64 QQFEGH-------YRCYASNDYGTAMTQSVQVIVEAQPVLPKQQQVHKESYEGESIILSC 116 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG----GNLVIQDARQTDAGRYQCIARNA 185 PP S P ++W + + + +DG NL+ D+R TD Y C A+ Sbjct: 117 NPPESSTPPVIHWMDKLMVHISQSERVLVGLDGKLYFSNLLRNDSR-TD---YMCNAQYL 172 Query: 186 AGTR---ESAIATLKIHI-------KPYLI--TGPED-VVAQTGSSVTFQCRVGGDPLPD 232 A ES I+ + KP+ TGP V+A G VT +C G P P Sbjct: 173 AARTILTESVISLTVVPSNDVAQARKPHFFKHTGPHSSVLALRGHKVTLECIPKGLPTPK 232 Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292 V W++ G G++ + +++ L D+GEY C+A NS G + S +TV Sbjct: 233 VEWKKKDGRLGETSGQLDK-HNRWFHFESIGLNDDGEYECKAWNSHGFTTHSFTVTVEAA 291 Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352 P P S G R C A G P P++ WS+ G R I ++ +V G Sbjct: 292 PYWVKKPASQLYSPGETVRLDCQAEGIPTPSITWSING-RNI----TEVEEEPRRSVSGG 346 Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412 V +L D D+ C A N GS+ + L V + PP I+T+ + Sbjct: 347 VLIL--RDVVFADTA-VYQCEATNKHGSALLNTFLHVV---ELPPQILTSDGLLYRVTEG 400 Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472 + C +P P I GTLV+ ++D D+G Y+C S + Sbjct: 401 RNILMDCEVFGSPRPHITC------------------GTLVISEVDHDDAGVYSC--SVK 440 Query: 473 HGKYV 477 H V Sbjct: 441 HNNNV 445 Score = 101 bits (241), Expect = 2e-19 Identities = 85/297 (28%), Positives = 135/297 (45%), Gaps = 38/297 (12%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG---VLVVSDTHRSILP 62 VT APY +++P + + L+C+A G P+P+I W G V + RS+ Sbjct: 286 VTVEAAPYWVKKPASQLYSPGETVRLDCQAEGIPTPSITWSINGRNITEVEEEPRRSV-- 343 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK-QSAQ 121 +GG+ LR V +D VY CEATN +G+A N LHV L + + + Sbjct: 344 SGGVLILRDV---VFADTAVYQCEATNKHGSALL-NTFLHVVELPPQILTSDGLLYRVTE 399 Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181 G ++++C GSP P++ G LVI + DAG Y C Sbjct: 400 GRNILMDC-EVFGSPRPHITC--------------------GTLVISEVDHDDAGVYSCS 438 Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP-LP--DVLWRRS 238 ++ S A L+++ + + P+++ G++ C DP LP V+WRR Sbjct: 439 VKH--NNNVSINAHLEVYNRTVIPAPPQNLRFLRGTNALLTCGFYTDPRLPPAQVVWRRD 496 Query: 239 AGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293 G+ + V +DG+L++ N+ D +YSCE + + V A G +TV D P Sbjct: 497 GHKLMGSETANKYSVFEDGTLKVSNIQFNDSAQYSCEVISLLDHVKAMGSITVVDRP 553 Score = 98.7 bits (235), Expect = 8e-19 Identities = 157/674 (23%), Positives = 252/674 (37%), Gaps = 102/674 (15%) Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRY 178 +G V LEC+P +G P P V WKK L G++ L D N + D G Y Sbjct: 215 RGHKVTLECIP-KGLPTPKVEWKKKDGRL---GETSGQL-DKHNRWFHFESIGLNDDGEY 269 Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238 +C A N+ G + T+ + PY + P + G +V C+ G P P + W S Sbjct: 270 ECKAWNSHGFTTHSF-TVTVEAAPYWVKKPASQLYSPGETVRLDCQAEGIPTPSITW--S 326 Query: 239 AGGGNMPLGRV---KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPS 294 G N+ + + G L L +V+ AD Y CEA N G+ + +L V + PP Sbjct: 327 INGRNITEVEEEPRRSVSGGVLILRDVVFADTAVYQCEATNKHGSALLNTFLHVVELPPQ 386 Query: 295 INLSPNSV-NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353 I S + V G C G P P H T Sbjct: 387 ILTSDGLLYRVTEGRNILMDCEVFGSPRP----------------------HITC----- 419 Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413 L I++ D +D+ CS V + + + L V + P P P N + Sbjct: 420 GTLVISEVDHDDA-GVYSCS-VKHNNNVSINAHLEVYNRTVIPAP-----PQNLRFLRGT 472 Query: 414 MAVFPC---TAICTPEPIIAWYFEGEALIQNHRRN---VTNDGTLVLKDLDKSDSGTYTC 467 A+ C T P + W +G L+ + N V DGTL + ++ +DS Y+C Sbjct: 473 NALLTCGFYTDPRLPPAQVVWRRDGHKLMGSETANKYSVFEDGTLKVSNIQFNDSAQYSC 532 Query: 468 VASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527 S L+D ++ + V P PP VTD ++TL+W+ Sbjct: 533 EVIS-----------LLD-----HVKAMGSITVVDRPDPPKYLSLAEVTDHNLTLNWTPG 576 Query: 528 NKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIV 587 + +S ++ + VE F E +T W + + +V SL P TY F V Sbjct: 577 S-AHNSPMIDFIVE-FREE----QHTEGKKWKWEEMKKVPADVQHVQLSLRPFCTYRFRV 630 Query: 588 RTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNN-ILTDHIVELIEATPIDS 646 N G S PS SD+ YR + + D + + D Sbjct: 631 IAVNEVGRSDPSEPSDT---------------------YRTSPAVPDRNPTGVRSESADP 669 Query: 647 KTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFF 706 ++ + W+ ++ Y G + + + + F + + YT +E Sbjct: 670 DSLVITWDEMDKMYHNGHGFLYEVSWREARKRDARWNSAEVKSPPFLVQNTGTYTPFEIK 729 Query: 707 LIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITG 766 + G + + +D P PP ++ ++N +TV +KW Q G++ G Sbjct: 730 VKAVNSLGSGPAPEPEIGHSGEDKPAEPPTGVKTTVIN-STVTVKWD--AAQDVRGLLLG 786 Query: 767 YNVVVNWLDVPANK 780 Y + + L P + Sbjct: 787 YKIHILRLGPPTER 800 Score = 91.9 bits (218), Expect = 1e-16 Identities = 99/383 (25%), Positives = 158/383 (41%), Gaps = 43/383 (11%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80 V R TL C G P+P + W K + + + L +F + G +D Sbjct: 211 VLALRGHKVTLECIPKGLPTPKVEWKKKDGRLGETSGQ--LDKHNRWFHFESIGL--NDD 266 Query: 81 GVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139 G Y C+A NS+G T S T+ A + +P S+ + G+TV L+C G P P+ Sbjct: 267 GEYECKAWNSHGFTTHSFTVTVEAAPYWVK---KPASQLYSPGETVRLDC-QAEGIPTPS 322 Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199 + W NG+ + + V GG L+++D D YQC A N G+ + Sbjct: 323 ITWSINGRNITEVEEEPRRSVSGGVLILRDVVFADTAVYQCEATNKHGSALLNTFLHVVE 382 Query: 200 IKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLR 258 + P ++T + T G ++ C V G P P + G+L Sbjct: 383 LPPQILTSDGLLYRVTEGRNILMDCEVFGSPRPHITC-------------------GTLV 423 Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC---T 315 + V D G YSC +++ VS + +L VY+ I P ++ G A TC T Sbjct: 424 ISEVDHDDAGVYSCSVKHN-NNVSINAHLEVYNRTVIPAPPQNLRFLRGTNALLTCGFYT 482 Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375 P + W +G++ + + +KY +VF+ T L +++ NDS C + Sbjct: 483 DPRLPPAQVVWRRDGHK--LMGSETANKY---SVFEDGT-LKVSNIQFNDSAQ-YSCEVI 535 Query: 376 NYAGSSFVRGKLTVTSDDDRPPP 398 + G +TV DRP P Sbjct: 536 SLLDHVKAMGSITVV---DRPDP 555 Score = 50.8 bits (116), Expect = 2e-04 Identities = 37/128 (28%), Positives = 58/128 (45%), Gaps = 5/128 (3%) Query: 693 EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKW 752 E+T LR ++ YE + + K EG S+ T + P GPP ++ + + T+V L W Sbjct: 835 EVTGLRLFSLYELSVTAYNSKGEGPHSDPHRFSTPEGAP-GPPASLRLQSPSETSVILYW 893 Query: 753 SPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAA 812 +PP NGI+ GY V+ AN + + T + +L Y ++ A Sbjct: 894 APP--TEANGILLGY--VIQHKQEGANSESLLQMISDPSVTHFELHHLDPNSYYIFKVIA 949 Query: 813 ETIIGLGP 820 T G GP Sbjct: 950 YTAAGEGP 957 Score = 48.0 bits (109), Expect = 0.002 Identities = 76/365 (20%), Positives = 133/365 (36%), Gaps = 36/365 (9%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG--GGNMPLGRVKVLDDGSLRL 259 P L PE + A + + C+ G+P P W + + LG +K ++ L+ Sbjct: 6 PVLSEVPESITAFSPVDIHLPCKAKGNPPPTFHWMKDGVLIRSGLHLGTLKAEEEEPLQ- 64 Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES--GNVARFTCTAT 317 EG Y C A N G + + + V+ ES G +C Sbjct: 65 -----QFEGHYRCYASNDYGTAMTQSVQVIVEAQPVLPKQQQVHKESYEGESIILSCNPP 119 Query: 318 -GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376 P + W ++ ++ S DG L ++ +NDSR +C+A Sbjct: 120 ESSTPPVIHWM---DKLMVHISQSE---RVLVGLDGK--LYFSNLLRNDSRTDYMCNAQY 171 Query: 377 YAGSSFVRGK---LTVTSDDD----RPPPIITN-GPSNQTLPIKSMAV-FPCTAICTPEP 427 A + + LTV +D R P + GP + L ++ V C P P Sbjct: 172 LAARTILTESVISLTVVPSNDVAQARKPHFFKHTGPHSSVLALRGHKVTLECIPKGLPTP 231 Query: 428 IIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD-S 486 + W + L + + ++ + + +D G Y C A + HG S + V+ + Sbjct: 232 KVEWKKKDGRLGETSGQLDKHNRWFHFESIGLNDDGEYECKAWNSHGFTTHSFTVTVEAA 291 Query: 487 PI---NPNIHFFRAADVSSL----PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQ 539 P P + + L G PT IT ++ ++T + + S +L + Sbjct: 292 PYWVKKPASQLYSPGETVRLDCQAEGIPTPSITWSINGRNITEVEEEPRRSVSGGVLILR 351 Query: 540 VEVFS 544 VF+ Sbjct: 352 DVVFA 356 Score = 36.7 bits (81), Expect = 3.9 Identities = 25/79 (31%), Positives = 37/79 (46%), Gaps = 4/79 (5%) Query: 689 VSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTV 748 V+ FE+ L + Y F +I + EG P R A L+ V PP N+ + + TT+ Sbjct: 929 VTHFELHHLDPNSYYIFKVIAYTAAGEGPPIQLRGATMLEGV---PPSNVTI-VTGTTSF 984 Query: 749 HLKWSPPELQLQNGIITGY 767 +L W P E +G Y Sbjct: 985 NLSWVPEERNRNHGFHVEY 1003 >UniRef50_Q92823 Cluster: Neuronal cell adhesion molecule precursor; n=22; Euteleostomi|Rep: Neuronal cell adhesion molecule precursor - Homo sapiens (Human) Length = 1304 Score = 131 bits (316), Expect = 1e-28 Identities = 139/497 (27%), Positives = 201/497 (40%), Gaps = 47/497 (9%) Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175 +K+ +G+ + LEC+ G P P +YW K L + ++ L I + D+ Sbjct: 279 NKEELRGNVLSLECIA-EGLPTPIIYWAKEDGML--PKNRTVYKNFEKTLQIIHVSEADS 335 Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235 G YQCIA+NA G I+ +++ PY IT P+++V G T CR G+P P + W Sbjct: 336 GNYQCIAKNALGAIHHTIS-VRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISW 394 Query: 236 RRSAGGGNM-PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-DPP 293 + + P + +D ++ NV Y C A N G + A+ ++ V +PP Sbjct: 395 LTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPP 454 Query: 294 SINLSPNSV-NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA-VFD 351 I N++ V + A C G P PT+ W F G H V Sbjct: 455 RILTPANTLYQVIANRPALLDCAFFGSPLPTIEW---------FKGAKGSALHEDIYVLH 505 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411 L I K DS T C A N G + L + + P I P + Sbjct: 506 ENGTLEIPVAQK-DSTGTYTCVARNKLGMAKNEVHLEI-----KDPTWIVKQPEYAVVQR 559 Query: 412 KSMAVFPCTAIC--TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469 SM F C T + W + L + R V D LV+ D+ DSGTYTCVA Sbjct: 560 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH-LVVADVSDDDSGTYTCVA 618 Query: 470 SSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWS---Q 526 ++ S L V +P P A V +P PP + D SV LSW+ Sbjct: 619 NTTLDSVSASAVLSVVAP-TPT-----PAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDD 672 Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFI 586 NN + I+ Y+ + + L + T + QT +K L P + Y F Sbjct: 673 NNSPITKFIIEYE-DAMHKPGLWHHQTEVSGT----------QTTAQLK-LSPYVNYSFR 720 Query: 587 VRTENSHGLSGPSPVSD 603 V NS G S PS S+ Sbjct: 721 VMAVNSIGKSLPSEASE 737 Score = 107 bits (256), Expect = 2e-21 Identities = 91/290 (31%), Positives = 130/290 (44%), Gaps = 21/290 (7%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSDTHRSILPAGGLF 67 APY I P ++ ++ + TL CRA G+P P I W GV + D R I G Sbjct: 360 APYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKI--DGDTI 417 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR-LEPESK--QSAQGDT 124 R + VY C A+N YG A V VL E R L P + Q Sbjct: 418 IFSNVQER---SSAVYQCNASNEYGYLL---ANAFVNVLAEPPRILTPANTLYQVIANRP 471 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 +L+C GSP P + W K + D + L + G L I A++ G Y C+ARN Sbjct: 472 ALLDC-AFFGSPLPTIEWFKGAKGSALHEDIYV-LHENGTLEIPVAQKDSTGTYTCVARN 529 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD--VLWRRSAGGG 242 G ++ + L+I +++ PE V Q GS V+F+C+V D VLW + Sbjct: 530 KLGMAKNEV-HLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKD--NR 586 Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292 +P +D L + +V D G Y+C A ++ +VSAS L+V P Sbjct: 587 ELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAP 636 Score = 101 bits (241), Expect = 2e-19 Identities = 183/808 (22%), Positives = 308/808 (38%), Gaps = 77/808 (9%) Query: 30 TLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88 +L C A G P+P I W K G+L + T L+ H +D+G Y C A Sbjct: 289 SLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT----LQIIHVS-EADSGNYQCIAK 343 Query: 89 NSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147 N+ G T+ V V + + P++ + G+ L C G+P+P + W NG Sbjct: 344 NALGAIHH---TISVRVKAAPYWITAPQNLVLSPGEDGTLICRA-NGNPKPRISWLTNGV 399 Query: 148 TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG 207 + D +DG ++ + ++ + YQC A N G A A + + +P I Sbjct: 400 PIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYL-LANAFVNVLAEPPRILT 458 Query: 208 PEDVVAQTGSS--VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA 265 P + + Q ++ C G PLP + W + A G + + ++G+L + Sbjct: 459 PANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKD 518 Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA--TGRPEPT 323 G Y+C A N +G +L + DP I P V+ G++ F C T Sbjct: 519 STGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLT 578 Query: 324 MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383 + W ++ NR + P R T D + V ++D D T C A S Sbjct: 579 VLW-LKDNREL--PSDER----FTVDKDHLVVADVSD----DDSGTYTCVANTTLDSVSA 627 Query: 384 RGKLTVTSDDDRPPPI--ITNGPSNQTLP---IKSMAVFPCTAICTPEPIIAWYFEGEAL 438 L+V + P P+ + N P + L KS+ + PI + E E Sbjct: 628 SAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDA 687 Query: 439 IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV-WSGALLVDSPINPNIHFFRA 497 + H+ + + T V SGT T A + YV +S ++ + I ++ + Sbjct: 688 M--HKPGLWHHQTEV--------SGTQT-TAQLKLSPYVNYSFRVMAVNSIGKSLPSEAS 736 Query: 498 ADVSSLPGPPTKPITH----NVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNT 553 + P K T ++ ++W N S+ G Q +V R+ G++ Sbjct: 737 EQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNG-PGLQYKVSWRQK-DGDDE 794 Query: 554 PRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNS 613 + VV+A + + Y+V + Y+ V+ N G + P P G+D Sbjct: 795 WTS----VVVA---NVSKYIVSGTPTFVPYLIKVQALNDMGFA-PEPAVVMGHSGEDLPM 846 Query: 614 LWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDN 673 + G R N++ + E + P+ K+I+ + YY + R + Sbjct: 847 VAPG-------NVRVNVVNSTLAE-VHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRH 898 Query: 674 ITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDG 733 I E K + + + L ++ Y + K EG S RV T + VP Sbjct: 899 I----EKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSA 954 Query: 734 PPINIEMFILNTT--TVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQ 791 P + I+N T ++ L+W PP NGI+T Y + ++ + Sbjct: 955 PS---SLKIVNPTLDSLTLEWDPP--SHPNGILTEYTLKYQPINSTHELGPLVDLKIPAN 1009 Query: 792 ATSLIMTNLTSGVSYSVQIAAETIIGLG 819 T + NL Y A+T G G Sbjct: 1010 KTRWTLKNLNFSTRYKFYFYAQTSAGSG 1037 Score = 68.1 bits (159), Expect = 1e-09 Identities = 52/181 (28%), Positives = 79/181 (43%), Gaps = 10/181 (5%) Query: 10 EAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGL 66 + P I +Q P D + + + C A G P P+ W + G + D ++ P G Sbjct: 44 QPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGT 103 Query: 67 FFLRA-THGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGD 123 + + G+ + GVY C A N G A S N + + L + +LEP + QS G Sbjct: 104 LIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQS--GQ 161 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIA 182 ++VL C PP G P P ++W N L + R+ G+L + D Y C A Sbjct: 162 SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSE-RVSQGLNGDLYFSNVLPEDTREDYICYA 220 Query: 183 R 183 R Sbjct: 221 R 221 Score = 58.4 bits (135), Expect = 1e-06 Identities = 67/305 (21%), Positives = 116/305 (38%), Gaps = 30/305 (9%) Query: 200 IKPYLIT--GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257 ++P IT P+D + ++ QC G P P W R+ ++ + + G+ Sbjct: 43 VQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTG 102 Query: 258 RLDNVILAD------EGEYSCEAENSVGAVSASGYLT--VYDPPSINLSPNSVNVESGNV 309 L I+++ EG Y C A N GA ++ + P + ++SG Sbjct: 103 TLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQS 162 Query: 310 ARFTCTAT-GRPEPTMFWSVEGNRTI-----IFPGMSRDKYHATAV-----FDGVTVLTI 358 C G P P +FW + + + G++ D Y + + D + Sbjct: 163 LVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARF 222 Query: 359 NDTDKNDSRNTIVCSAVNYAG-SSFVRGKLTVT------SDDDRPPPIIT--NGPSNQTL 409 N T + I ++ + + L+ T S +RPP +T SN+ Sbjct: 223 NHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEE 282 Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469 ++ C A P PII W E L +N + TL + + ++DSG Y C+A Sbjct: 283 LRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIA 342 Query: 470 SSRHG 474 + G Sbjct: 343 KNALG 347 Score = 54.4 bits (125), Expect = 2e-05 Identities = 56/218 (25%), Positives = 90/218 (41%), Gaps = 12/218 (5%) Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVI----QDARQTDAGR 177 + +V++C +G P P+ W +NG D D + + G G L+I + +T G Sbjct: 62 ENIVIQC-EAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGV 120 Query: 178 YQCIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLW 235 YQC ARN G S ++ P + E + Q+G S+ CR G P P + W Sbjct: 121 YQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFW 180 Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGE-YSCEAE-NSVGAVSASGYLTVYDPP 293 ++ RV +G L NV+ D E Y C A N + ++V Sbjct: 181 MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISV-KVI 239 Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGN 331 S++ +++ + F + R P F + EGN Sbjct: 240 SVDELNDTIAANLSD-TEFYGAKSSRERPPTFLTPEGN 276 >UniRef50_Q08CM9 Cluster: Zgc:152904; n=12; Euteleostomi|Rep: Zgc:152904 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 809 Score = 130 bits (315), Expect = 2e-28 Identities = 108/371 (29%), Positives = 165/371 (44%), Gaps = 31/371 (8%) Query: 29 ATLNCRAGGSPSPAIRW-YKGGVLVVSDTHR-SILPAGGLFFLRATHGRVHSDAGVYWCE 86 A + C SP PA+ W YK + R +LP L L+ G+ +D G Y CE Sbjct: 101 AEVVCDVISSPVPAVSWFYKNREITSEPNSRFQVLPTNNLQILKV--GK--ADEGAYRCE 156 Query: 87 A-TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD---TVVLECLPPRGSPEPNVYW 142 A + G R+ + V V P+ +A D +V C+ GSP+P V W Sbjct: 157 ARVEARGEIDFRDIVVQVNV--PPVLSVPQQSFNATADYQESVTFTCVTS-GSPDPQVTW 213 Query: 143 KKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200 G + ++ ++GG L +++ +QTD G Y C A N AG+ ES + LK+ + Sbjct: 214 YWKGHAIEHSEQYVLNTMNGGKSTLTVKNIKQTDGGPYMCRASNKAGSSESQLF-LKVFV 272 Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG------RVKVLD- 253 +P+ IT +V A GS+ C G+PLP++ WRR++ G + G RV+V Sbjct: 273 QPH-ITQLRNVTAVEGSAAMISCTAEGEPLPEISWRRASDGHSFTDGEKSKDGRVEVRGR 331 Query: 254 --DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVAR 311 L + V L+D G + CEA + +G S +L + P + + GN Sbjct: 332 HGKSMLTISGVQLSDWGRFDCEALSRIGGHQKSMFLDIEYAPKFQTNQSIFYSWEGNPVN 391 Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371 +C P TM W E TI G S + H+T DG ++L + D Sbjct: 392 ISCEVKSNPAATMLWRRE-RFTISSQGTSNIRIHST---DGRSLLEVTPVSDRDF-GRYN 446 Query: 372 CSAVNYAGSSF 382 C+A N G+ + Sbjct: 447 CTARNNIGARY 457 Score = 109 bits (263), Expect = 3e-22 Identities = 127/517 (24%), Positives = 213/517 (41%), Gaps = 37/517 (7%) Query: 33 CRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSY 91 C A G P +I W+ G ++S+ R I+ G+ + + +AG+Y C+A ++ Sbjct: 11 CTAIGEPV-SINWFSPQGERIISN-ERVIVHTEGVRSRLTIYNAIIENAGIYRCQAADAK 68 Query: 92 GTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150 G +S+ AT+ + + ++ FR ++ QGD + C SP P V W + + Sbjct: 69 G--QSQEATVVLEIYQKLTFREVKTPQEFRQGDDAEVVC-DVISSPVPAVSWFYKNREIT 125 Query: 151 FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR-NAAGTRESAIATLKIHIKPYLITGPE 209 + +SR ++ NL I + D G Y+C AR A G + +++++ P L + Sbjct: 126 SEPNSRFQVLPTNNLQILKVGKADEGAYRCEARVEARGEIDFRDIVVQVNVPPVLSVPQQ 185 Query: 210 --DVVAQTGSSVTFQCRVGGDPLPDVLWR-RSAGGGNMPLGRVKVLDDG--SLRLDNVIL 264 + A SVTF C G P P V W + + + ++ G +L + N+ Sbjct: 186 SFNATADYQESVTFTCVTSGSPDPQVTWYWKGHAIEHSEQYVLNTMNGGKSTLTVKNIKQ 245 Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTM 324 D G Y C A N G+ + +L V+ P I N VE G+ A +CTA G P P + Sbjct: 246 TDGGPYMCRASNKAGSSESQLFLKVFVQPHITQLRNVTAVE-GSAAMISCTAEGEPLPEI 304 Query: 325 FWSVEGNRTIIFPG-MSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383 W + G S+D G ++LTI+ +D C A++ G Sbjct: 305 SWRRASDGHSFTDGEKSKDGRVEVRGRHGKSMLTISGVQLSD-WGRFDCEALSRIGGH-- 361 Query: 384 RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR 443 + ++ D + P TN + + + C P + W E + Sbjct: 362 --QKSMFLDIEYAPKFQTNQSIFYSWEGNPVNI-SCEVKSNPAATMLWRRERFTISSQGT 418 Query: 444 RNV---TNDGTLVLK--DLDKSDSGTYTCVA----SSRHGKYVWSGALLVDSPINPNIHF 494 N+ + DG +L+ + D G Y C A +R+ +++ + A + SP + + Sbjct: 419 SNIRIHSTDGRSLLEVTPVSDRDFGRYNCTARNNIGARYQEFILAQADVPSSPYSVRMTA 478 Query: 495 F--RAADVS-----SLPGPPTKPITHNVTDTSVTLSW 524 R A VS S G P N DTS W Sbjct: 479 VSQRMATVSFMKPDSHGGVPISFYIINYRDTSSAQEW 515 Score = 87.4 bits (207), Expect = 2e-15 Identities = 84/306 (27%), Positives = 129/306 (42%), Gaps = 30/306 (9%) Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWY-KGGVLVVSDTHRSILPAGGLFFLRATHG 74 +Q + T + T C GSP P + WY KG + S+ + GG L + Sbjct: 184 QQSFNATADYQESVTFTCVTSGSPDPQVTWYWKGHAIEHSEQYVLNTMNGGKSTLTVKNI 243 Query: 75 RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRG 134 + +D G Y C A+N G++ S+ L + V + + + + +G ++ C G Sbjct: 244 K-QTDGGPYMCRASNKAGSSESQ---LFLKVFVQPHITQLRNVTAVEGSAAMISC-TAEG 298 Query: 135 SPEPNVYWKKNGQTLLF-DG----DSRMHLVDGGN----LVIQDARQTDAGRYQCIARNA 185 P P + W++ F DG D R+ V G + L I + +D GR+ C A + Sbjct: 299 EPLPEISWRRASDGHSFTDGEKSKDGRVE-VRGRHGKSMLTISGVQLSDWGRFDCEALSR 357 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR------SA 239 G + ++ L I P T + G+ V C V +P +LWRR S Sbjct: 358 IGGHQKSM-FLDIEYAPKFQTNQSIFYSWEGNPVNISCEVKSNPAATMLWRRERFTISSQ 416 Query: 240 GGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298 G N+ R+ D S L + V D G Y+C A N++GA L D PS S Sbjct: 417 GTSNI---RIHSTDGRSLLEVTPVSDRDFGRYNCTARNNIGARYQEFILAQADVPS---S 470 Query: 299 PNSVNV 304 P SV + Sbjct: 471 PYSVRM 476 Score = 70.5 bits (165), Expect = 3e-10 Identities = 69/269 (25%), Positives = 112/269 (41%), Gaps = 22/269 (8%) Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSC 272 G S F C G+P+ + W G + RV V +G L + N I+ + G Y C Sbjct: 4 GESKFFTCTAIGEPV-SINWFSPQGERIISNERVIVHTEGVRSRLTIYNAIIENAGIYRC 62 Query: 273 EAENSVG-AVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGN 331 +A ++ G + A+ L +Y + G+ A C P P + W + N Sbjct: 63 QAADAKGQSQEATVVLEIYQKLTFREVKTPQEFRQGDDAEVVCDVISSPVPAVSWFYK-N 121 Query: 332 RTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA-VNYAGSSFVRGKLTVT 390 R I SR + T + + +L + D+ R C A V G R + Sbjct: 122 REITSEPNSRFQVLPT---NNLQILKVGKADEGAYR----CEARVEARGEIDFRD---IV 171 Query: 391 SDDDRPPPIITNGPS-NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL--IQNHRRNVT 447 + PP + S N T + F C +P+P + WY++G A+ + + N Sbjct: 172 VQVNVPPVLSVPQQSFNATADYQESVTFTCVTSGSPDPQVTWYWKGHAIEHSEQYVLNTM 231 Query: 448 NDG--TLVLKDLDKSDSGTYTCVASSRHG 474 N G TL +K++ ++D G Y C AS++ G Sbjct: 232 NGGKSTLTVKNIKQTDGGPYMCRASNKAG 260 Score = 58.4 bits (135), Expect = 1e-06 Identities = 59/221 (26%), Positives = 94/221 (42%), Gaps = 22/221 (9%) Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLFFLRATH 73 I Q +VT A ++C A G P P I W + +D +S G +R H Sbjct: 276 ITQLRNVTAVEGSAAMISCTAEGEPLPEISWRRASDGHSFTDGEKS---KDGRVEVRGRH 332 Query: 74 GRVH--------SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 G+ SD G + CEA + G ++ L + +F+ S +G+ V Sbjct: 333 GKSMLTISGVQLSDWGRFDCEALSRIG-GHQKSMFLDIE-YAPKFQTNQSIFYSWEGNPV 390 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDS--RMHLVDGGNLV-IQDARQTDAGRYQCIA 182 + C + +P + W++ T+ G S R+H DG +L+ + D GRY C A Sbjct: 391 NISC-EVKSNPAATMLWRRERFTISSQGTSNIRIHSTDGRSLLEVTPVSDRDFGRYNCTA 449 Query: 183 RNAAGTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTF 221 RN G R E +A + PY + V+Q ++V+F Sbjct: 450 RNNIGARYQEFILAQADVPSSPYSVR--MTAVSQRMATVSF 488 >UniRef50_Q03696 Cluster: Neuronal-glial cell adhesion molecule precursor; n=2; Gallus gallus|Rep: Neuronal-glial cell adhesion molecule precursor - Gallus gallus (Chicken) Length = 1266 Score = 130 bits (315), Expect = 2e-28 Identities = 134/496 (27%), Positives = 194/496 (39%), Gaps = 37/496 (7%) Query: 10 EAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR--SILPAGGL 66 + P + E+P + + V L C A G+P RW + V + H S++P G Sbjct: 34 QPPELTEEPPEQLVVFPSDDIVLKCVATGNPPVQYRWSREDQPFVPEEHGGVSVVPGSGT 93 Query: 67 FFLRAT-HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 + AT R+ G + C ATN+ GTA S A + + + + + +GD V Sbjct: 94 LVINATLAARLQ---GRFRCFATNALGTAVSPEANVIAENTPQWPKEKVTPVEVEEGDPV 150 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIARN 184 VL C PP + P +YW N + D R+ + GNL +A D+ Y C A Sbjct: 151 VLPCDPPESAVPPKIYWL-NSDIVHIAQDERVSMGQDGNLYFSNAMVGDSHPDYICHAHF 209 Query: 185 AAGTRESAIATLKIHIKPY--------LITGPED----VVAQTGSSVTFQCRVGGDPLPD 232 L + + P + P D +A G SV +C G P P Sbjct: 210 LGPRTIIQKEPLDLRVAPSNAVRSRRPRLLLPRDPQTTTIALRGGSVVLECIAEGLPTPW 269 Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292 V WRR G +P G + +LRL V +D+GEY C AEN G + +TV Sbjct: 270 VRWRR-LNGPLLPGGVGNF--NKTLRLWGVTESDDGEYECVAENGRGTARGTHSVTVEAA 326 Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352 P P S G AR C G+P P + WS+ G I G R A Sbjct: 327 PYWVRRPQSGVFGPGETARLDCEVGGKPRPQIQWSING-VPIEAAGAERRWLRGGA---- 381 Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412 L + + NDS + C A N G L V + P ++T + Sbjct: 382 ---LVLPELRPNDSA-VLQCEARNRHGPLLANAFLHVV---ELPLRMLTADEQRYEVVEN 434 Query: 413 SMAVFPCTAICTPEPIIAWYFEG-EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471 C P P + W E +Q+ R V +G+L + + D G YTC+A + Sbjct: 435 QTVFLHCRTFGAPAPNVEWLTPTLEPALQDDRSFVFTNGSLRVSAVRGGDGGVYTCMAQN 494 Query: 472 RHGKYVWSGALLVDSP 487 H + L V +P Sbjct: 495 AHSNGSLTALLEVRAP 510 Score = 111 bits (266), Expect = 1e-22 Identities = 93/310 (30%), Positives = 127/310 (40%), Gaps = 16/310 (5%) Query: 18 PLDVTVA-RHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH--G 74 P T+A R L C A G P+P +RW + + +LP G F + G Sbjct: 244 PQTTTIALRGGSVVLECIAEGLPTPWVRWRR--------LNGPLLPGGVGNFNKTLRLWG 295 Query: 75 RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRG 134 SD G Y C A N GTAR ++ A + P+S G+T L+C G Sbjct: 296 VTESDDGEYECVAENGRGTARGTHSVTVEAA--PYWVRRPQSGVFGPGETARLDC-EVGG 352 Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194 P P + W NG + G R L GG LV+ + R D+ QC ARN G + Sbjct: 353 KPRPQIQWSINGVPIEAAGAERRWL-RGGALVLPELRPNDSAVLQCEARNRHGPLLANAF 411 Query: 195 TLKIHIKPYLITGPEDVVAQTGSSVTF-QCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD 253 + + ++T E + F CR G P P+V W + R V Sbjct: 412 LHVVELPLRMLTADEQRYEVVENQTVFLHCRTFGAPAPNVEWLTPTLEPALQDDRSFVFT 471 Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313 +GSLR+ V D G Y+C A+N+ S + L V P I+ P S + G F Sbjct: 472 NGSLRVSAVRGGDGGVYTCMAQNAHSNGSLTALLEVRAPTRISAPPRSATAKKGETVTFH 531 Query: 314 CTATGRPEPT 323 C AT P T Sbjct: 532 CGATFDPAVT 541 Score = 103 bits (248), Expect = 2e-20 Identities = 89/304 (29%), Positives = 125/304 (41%), Gaps = 17/304 (5%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAG 64 VT APY + +P + A L+C GG P P I+W GV + + R L G Sbjct: 321 VTVEAAPYWVRRPQSGVFGPGETARLDCEVGGKPRPQIQWSINGVPIEAAGAERRWLRGG 380 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK-QSAQGD 123 L +D+ V CEA N +G + NA LHV L E + + + Sbjct: 381 ALVLPELR----PNDSAVLQCEARNRHGPLLA-NAFLHVVELPLRMLTADEQRYEVVENQ 435 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183 TV L C G+P PNV W D R + G+L + R D G Y C+A+ Sbjct: 436 TVFLHC-RTFGAPAPNVEWLTPTLEPALQ-DDRSFVFTNGSLRVSAVRGGDGGVYTCMAQ 493 Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPL---PDVLWRRSAG 240 N A + S A L++ + P A+ G +VTF C DP ++ W R G Sbjct: 494 N-AHSNGSLTALLEVRAPTRISAPPRSATAKKGETVTFHCGATFDPAVTPGELRWLR--G 550 Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLSP 299 G +P + + + NV DEG C A + + A L V PPS +L Sbjct: 551 GQPLP-DDPRYSVAAEMTVSNVDYGDEGTIQCRASTPLDSAEAEAQLRVVGRPPSRDLQV 609 Query: 300 NSVN 303 V+ Sbjct: 610 MEVD 613 >UniRef50_Q1JUB3 Cluster: L1-like cell adhesion molecule; n=1; Dugesia japonica|Rep: L1-like cell adhesion molecule - Dugesia japonica (Planarian) Length = 1351 Score = 130 bits (314), Expect = 2e-28 Identities = 126/485 (25%), Positives = 201/485 (41%), Gaps = 40/485 (8%) Query: 12 PYIIEQPLDVTVARHQPAT-LNCRAGGSPSPAIRWYKGGVLV---VSDTHRSILPAGGLF 67 P + QP V ++ A L C A GSPSP W K + ++ + P G Sbjct: 26 PSFVYQPNKNEVYQNLEALMLRCVATGSPSPTYTWLKNNKVFDFSINVGRYTKWPNEGTM 85 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127 L + D G+Y C A NS+G A S + + A ++ +PE + QG+ ++L Sbjct: 86 ILALPND---DDDGIYQCIAENSHGKAYSIKSNVRRAEIQNFKNKDPEKITARQGEYLLL 142 Query: 128 ECLPPRGSPEPNVYWK--KNGQTLLFDGDSRMHLVDGGNLVIQD-ARQTDAGRYQCIARN 184 +C P P P V W+ KNG L S+ + GNL I + D ++ C N Sbjct: 143 KCEVPVCFPPPIVVWQKIKNGIAELIKESSKYVMDIDGNLYITGLTMEDDQAKFSCTVYN 202 Query: 185 -----AAGTRESAIATL--KIHIKPYL-ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 +E I + + ++ L + + + G + +C + G P P+ W Sbjct: 203 QRMRMTKSDKEHWITVIPGQSNLPVVLRFRSLQPMNGRVGDKLVLRCILSGYPSPNYKW- 261 Query: 237 RSAGGGNMPLGRVKVLDD--GSLRLDN-VILADEGEYSCEAENSVG--AVSASGYLTVYD 291 G L R + D G++ + N V AD+ + C EN+V + + V Sbjct: 262 TVKGQDKSILERPNFITDAGGAILIINPVTTADQDTFQCTGENAVSNIPIVIDFQVNVEM 321 Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG-NRTIIFPGMSRDKYHATAVF 350 P + + NV F+C A GRP P + W+V G G ++ K Sbjct: 322 TPILTTKLSDANVPYNGSHVFSCEAIGRPNPVITWTVNGVGLDTYLNGQNKRKI------ 375 Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410 G T+ N + + C+A NY G + G + V D P NGP + Sbjct: 376 -GNTIYLTNLLPGDHA--VFQCNASNYIGYDYSNGYINVLRD----KPEFINGPQATLIK 428 Query: 411 IKSM-AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469 ++ A C A P+ I+ W +G I R + ++G L++ L +DSGTYTC A Sbjct: 429 AENKPATINCQAFSAPKAIVTWTKDGFP-INGGRYMIQDNGDLLITKLITADSGTYTCTA 487 Query: 470 SSRHG 474 ++ +G Sbjct: 488 TNLYG 492 Score = 90.2 bits (214), Expect = 3e-16 Identities = 95/362 (26%), Positives = 145/362 (40%), Gaps = 29/362 (8%) Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180 GD +VL C+ G P PN W GQ + + + + G L+I D +QC Sbjct: 242 GDKLVLRCILS-GYPSPNYKWTVKGQDKSILERPNFITDAGGAILIINPVTTADQDTFQC 300 Query: 181 IARNAAGTRESAIA-TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239 NA I + + + P L T D S F C G P P + W + Sbjct: 301 TGENAVSNIPIVIDFQVNVEMTPILTTKLSDANVPYNGSHVFSCEAIGRPNPVITWTVNG 360 Query: 240 GGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-DPPSINL 297 G + L G+ K ++ L N++ D + C A N +G ++GY+ V D P Sbjct: 361 VGLDTYLNGQNKRKIGNTIYLTNLLPGDHAVFQCNASNYIGYDYSNGYINVLRDKPEFIN 420 Query: 298 SPNSVNVESGNV-ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356 P + +++ N A C A P+ + W+ +G FP ++ +Y D L Sbjct: 421 GPQATLIKAENKPATINCQAFSAPKAIVTWTKDG-----FP-INGGRYMIQDNGD----L 470 Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416 I DS T C+A N GS + G V R + P N + Sbjct: 471 LITKLITADS-GTYTCTATNLYGS--ISGTCVVFV---RQRTELMIRPINTWVYFGQEVK 524 Query: 417 FPCTA----ICTPEPIIAWYFEGEAL-IQNHRRNVTN--DGTLVLKDLDKSDSGTYTCVA 469 F CTA + T I WY + + I + R TN D +L++ +D+G YTC A Sbjct: 525 FVCTAKTDRLETQNLKIVWYKDNSPITIGPYERTNTNLQDNSLIIMGAQTTDTGIYTCNA 584 Query: 470 SS 471 ++ Sbjct: 585 TN 586 Score = 64.1 bits (149), Expect = 2e-08 Identities = 72/290 (24%), Positives = 111/290 (38%), Gaps = 17/290 (5%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFLR 70 P + + D V + +C A G P+P I W GV L ++ G +L Sbjct: 323 PILTTKLSDANVPYNGSHVFSCEAIGRPNPVITWTVNGVGLDTYLNGQNKRKIGNTIYLT 382 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ-SAQGDTVVLEC 129 + D V+ C A+N G S N ++V + EF P++ A+ + C Sbjct: 383 ---NLLPGDHAVFQCNASNYIGYDYS-NGYINVLRDKPEFINGPQATLIKAENKPATINC 438 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189 +P+ V W K+G + R + D G+L+I D+G Y C A N G+ Sbjct: 439 -QAFSAPKAIVTWTKDGFPI---NGGRYMIQDNGDLLITKLITADSGTYTCTATNLYGS- 493 Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP----DVLWRRSAGGGNM- 244 S + + + L+ P + G V F C D L ++W + + Sbjct: 494 ISGTCVVFVRQRTELMIRPINTWVYFGQEVKFVCTAKTDRLETQNLKIVWYKDNSPITIG 553 Query: 245 PLGRVKV-LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293 P R L D SL + D G Y+C A N + A L V P Sbjct: 554 PYERTNTNLQDNSLIIMGAQTTDTGIYTCNATNGLDFDVAYATLIVQGKP 603 Score = 62.5 bits (145), Expect = 7e-08 Identities = 54/199 (27%), Positives = 83/199 (41%), Gaps = 13/199 (6%) Query: 10 EAPYIIEQPLDVTV-ARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68 + P I P + A ++PAT+NC+A +P + W K G ++ I G L Sbjct: 414 DKPEFINGPQATLIKAENKPATINCQAFSAPKAIVTWTKDG-FPINGGRYMIQDNGDLLI 472 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128 + + +D+G Y C ATN YG+ S + V R E + P + G V Sbjct: 473 TKL----ITADSGTYTCTATNLYGSI-SGTCVVFVR-QRTELMIRPINTWVYFGQEVKFV 526 Query: 129 CLPPRGSPEP---NVYWKKNGQTLLFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCIARN 184 C E + W K+ + R + + +L+I A+ TD G Y C A N Sbjct: 527 CTAKTDRLETQNLKIVWYKDNSPITIGPYERTNTNLQDNSLIIMGAQTTDTGIYTCNATN 586 Query: 185 AAGTRESAIATLKIHIKPY 203 + A ATL + KP+ Sbjct: 587 GLDF-DVAYATLIVQGKPH 604 Score = 37.9 bits (84), Expect = 1.7 Identities = 20/84 (23%), Positives = 33/84 (39%), Gaps = 4/84 (4%) Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE----ALIQNHRRNVTNDGT 451 PP + N+ + C A +P P W + ++ N+GT Sbjct: 25 PPSFVYQPNKNEVYQNLEALMLRCVATGSPSPTYTWLKNNKVFDFSINVGRYTKWPNEGT 84 Query: 452 LVLKDLDKSDSGTYTCVASSRHGK 475 ++L + D G Y C+A + HGK Sbjct: 85 MILALPNDDDDGIYQCIAENSHGK 108 >UniRef50_UPI0000E4747A Cluster: PREDICTED: similar to neuroglian; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to neuroglian - Strongylocentrotus purpuratus Length = 762 Score = 129 bits (312), Expect = 4e-28 Identities = 107/334 (32%), Positives = 144/334 (43%), Gaps = 20/334 (5%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLR 70 P I+EQP VT + P TL CRA G+P P W K G L V R+ L G L Sbjct: 117 PSIVEQPESVTGDQRIPLTLPCRAIGTPEPTYYWEKDGSLFDVDSNDRTRLDGGNLVIES 176 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC- 129 T +D G Y C A N GTA S+ +A + + P Q +QG + L C Sbjct: 177 LT----TADDGQYQCFANNRLGTAMSQKIRTSLAFMEQFVNTAPAMVQMSQGQPLKLRCG 232 Query: 130 -LP--PRGSPEPNVYWKKNGQTLLFDG-DSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 P P G+P P +YW G D+R++ GNLV + +DA Y C+A N Sbjct: 233 GSPGVPNGNPAPLIYWTDAAPKPTPIGYDARINQDLEGNLVFSNVIASDAKGYYCLAINN 292 Query: 186 AGT-RESAIATLKIHIKP------YLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 G+ + S TL + P +L + P VA S +C G P P + W+R Sbjct: 293 VGSFQRSPKITLSVTDLPAVASAAHLDSHPAASEVANRTQSFKLKCIAFGYPTPVITWKR 352 Query: 238 SAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296 GRV + + G +L + V +DEG Y+C A N+ G S +TV P Sbjct: 353 GEEQLQSG-GRVSIEESGQALVISAVENSDEGTYTCVASNTGGDDEFSTVVTVESAPYFP 411 Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330 P G C + G P PT+ W V G Sbjct: 412 APPFDETKGPGESFDIECRSEGVPPPTVEWLVNG 445 Score = 107 bits (257), Expect = 2e-21 Identities = 88/346 (25%), Positives = 146/346 (42%), Gaps = 30/346 (8%) Query: 163 GNLVIQDARQTDAGRYQCIARNAAGTRES---------AIATLKIHIKPYLITGPEDVVA 213 G+L+I + ++ D+G Y+C A N+ ++ + TL P ++ PE V Sbjct: 69 GSLMINNVKKVDSGEYECTAENSIDGQDHEATGSATLIVLGTLLDDFPPSIVEQPESVTG 128 Query: 214 QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCE 273 +T CR G P P W + ++ LD G+L ++++ AD+G+Y C Sbjct: 129 DQRIPLTLPCRAIGTPEPTYYWEKDGSLFDVDSNDRTRLDGGNLVIESLTTADDGQYQCF 188 Query: 274 AENSVGAVSASGYLT--VYDPPSINLSPNSVNVESGNVARFTCTAT-----GRPEPTMFW 326 A N +G + T + +N +P V + G + C + G P P ++W Sbjct: 189 ANNRLGTAMSQKIRTSLAFMEQFVNTAPAMVQMSQGQPLKLRCGGSPGVPNGNPAPLIYW 248 Query: 327 SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386 T P + Y A D L ++ +D++ C A+N GS F R Sbjct: 249 ------TDAAPKPTPIGYDARINQDLEGNLVFSNVIASDAKG-YYCLAINNVGS-FQRSP 300 Query: 387 LTVTSDDDRPPPI----ITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQN 441 S D P + + P+ + ++ + C A P P+I W E L Sbjct: 301 KITLSVTDLPAVASAAHLDSHPAASEVANRTQSFKLKCIAFGYPTPVITWKRGEEQLQSG 360 Query: 442 HRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486 R ++ G LV+ ++ SD GTYTCVAS+ G +S + V+S Sbjct: 361 GRVSIEESGQALVISAVENSDEGTYTCVASNTGGDDEFSTVVTVES 406 Score = 64.9 bits (151), Expect = 1e-08 Identities = 64/236 (27%), Positives = 96/236 (40%), Gaps = 20/236 (8%) Query: 254 DGSLRLDNVILADEGEYSCEAENSVGA----VSASGYL----TVYD--PPSINLSPNSVN 303 +GSL ++NV D GEY C AENS+ + S L T+ D PPSI P SV Sbjct: 68 EGSLMINNVKKVDSGEYECTAENSIDGQDHEATGSATLIVLGTLLDDFPPSIVEQPESVT 127 Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363 + C A G PEPT +W +G+ +F S D+ T + G V+ T Sbjct: 128 GDQRIPLTLPCRAIGTPEPTYYWEKDGS---LFDVDSNDR---TRLDGGNLVIESLTTAD 181 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423 + + + A S +R L P + Q L ++ P Sbjct: 182 DGQYQCFANNRLGTAMSQKIRTSLAFMEQFVNTAPAMVQMSQGQPLKLR-CGGSPGVPNG 240 Query: 424 TPEPIIAWYF---EGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476 P P+I W + + + R N +G LV ++ SD+ Y C+A + G + Sbjct: 241 NPAPLIYWTDAAPKPTPIGYDARINQDLEGNLVFSNVIASDAKGYYCLAINNVGSF 296 Score = 60.5 bits (140), Expect = 3e-07 Identities = 40/124 (32%), Positives = 58/124 (46%), Gaps = 11/124 (8%) Query: 218 SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD--GSLRLDNVILADEGEYSCEAE 275 S F C G P P + W + G + G L++ GS+ ++NV D GEY C AE Sbjct: 475 SAKFICHFKGRPTPTITW--TFKGSVLTNGIKYTLNETEGSVVINNVKKVDSGEYECRAE 532 Query: 276 NSVGA----VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP---EPTMFWSV 328 N++ + S LTV +I LSP ++ + GN A F C EP ++W Sbjct: 533 NAIDGEDYEATGSATLTVLGKTTIYLSPANLMIREGNTATFQCEIMYDEELIEPYVYWMK 592 Query: 329 EGNR 332 +G R Sbjct: 593 DGQR 596 Score = 53.2 bits (122), Expect = 4e-05 Identities = 43/145 (29%), Positives = 59/145 (40%), Gaps = 7/145 (4%) Query: 4 DYVTSGEAPYIIEQPLDVTVA-RHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62 D A ++ P VA R Q L C A G P+P I W +G + S SI Sbjct: 308 DLPAVASAAHLDSHPAASEVANRTQSFKLKCIAFGYPTPVITWKRGEEQLQSGGRVSIEE 367 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122 +G + A +SD G Y C A+N+ G +T+ F P + G Sbjct: 368 SGQALVISAVE---NSDEGTYTCVASNTGGD--DEFSTVVTVESAPYFPAPPFDETKGPG 422 Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQ 147 ++ +EC G P P V W NGQ Sbjct: 423 ESFDIECRS-EGVPPPTVEWLVNGQ 446 Score = 50.4 bits (115), Expect = 3e-04 Identities = 27/96 (28%), Positives = 50/96 (52%), Gaps = 4/96 (4%) Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE-- 190 +G P P + W G ++L +G G++VI + ++ D+G Y+C A NA + Sbjct: 483 KGRPTPTITWTFKG-SVLTNGIKYTLNETEGSVVINNVKKVDSGEYECRAENAIDGEDYE 541 Query: 191 -SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV 225 + ATL + K + P +++ + G++ TFQC + Sbjct: 542 ATGSATLTVLGKTTIYLSPANLMIREGNTATFQCEI 577 Score = 42.7 bits (96), Expect = 0.059 Identities = 36/134 (26%), Positives = 53/134 (39%), Gaps = 9/134 (6%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 ++V A C G P+P I W +KG VL + G + D Sbjct: 468 LSVVEDDSAKFICHFKGRPTPTITWTFKGSVLTNGIKYTLNETEGSVVINNVKK----VD 523 Query: 80 AGVYWCEATNSY-GTARSRNATLHVAVL-REEFRLEPESKQSAQGDTVVLEC--LPPRGS 135 +G Y C A N+ G + + VL + L P + +G+T +C + Sbjct: 524 SGEYECRAENAIDGEDYEATGSATLTVLGKTTIYLSPANLMIREGNTATFQCEIMYDEEL 583 Query: 136 PEPNVYWKKNGQTL 149 EP VYW K+GQ L Sbjct: 584 IEPYVYWMKDGQRL 597 Score = 37.5 bits (83), Expect = 2.2 Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 1/58 (1%) Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN-DGTLVLKDLDKSDSGTYTCVASS 471 A F C P P I W F+G L + + +G++V+ ++ K DSG Y C A + Sbjct: 476 AKFICHFKGRPTPTITWTFKGSVLTNGIKYTLNETEGSVVINNVKKVDSGEYECRAEN 533 >UniRef50_Q4RZE9 Cluster: Chromosome undetermined SCAF14935, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF14935, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 735 Score = 129 bits (312), Expect = 4e-28 Identities = 86/275 (31%), Positives = 131/275 (47%), Gaps = 17/275 (6%) Query: 29 ATLNCRAGGSPSPAIRWYKGG----VLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYW 84 A L C+ G PSPAIRW K V D+ ++LP+G L R D+ +Y Sbjct: 20 ALLECKVSGEPSPAIRWQKNREDLPVTSEPDSQLAMLPSGSLQVSRVQP----PDSAMYR 75 Query: 85 CEATNSYGTARSRNATLHV----AVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139 C A N + +A L V + R +F P + G VVLEC G P P+ Sbjct: 76 CLADNPGSSRTGADAELRVLPEPGLPRSLQFLQRPSRVTALLGSDVVLEC-SASGYPTPS 134 Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199 + W+K G+ L+ + L+ G NL+I+ D+G Y C A N SA A L + Sbjct: 135 IQWRK-GEELIQSWSKKYSLLVGSNLIIRSVTDDDSGSYSCTAANR-NQNISATAELSVL 192 Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL 259 + P + P + A + V +C V G+P P V W ++ G +P +++D +L++ Sbjct: 193 VPPQFLNYPSNTYAYESTDVELECAVTGNPPPTVRWMKN-GEEVIPSDYFQMVDGSNLQI 251 Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294 ++ +DEG Y C AEN+ G+ A L + +P S Sbjct: 252 LGLVKSDEGFYQCVAENAAGSSQAMAQLLLREPVS 286 Score = 94.7 bits (225), Expect = 1e-17 Identities = 83/337 (24%), Positives = 138/337 (40%), Gaps = 31/337 (9%) Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG---GNMPLGRVKVLDDGSLRLDN 261 +T + V + G + +C+V G+P P + W+++ + P ++ +L GSL++ Sbjct: 6 VTPTKSVSSYLGDTALLECKVSGEPSPAIRWQKNREDLPVTSEPDSQLAMLPSGSLQVSR 65 Query: 262 VILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLS------PNSVNVESGNVARFTC 314 V D Y C A+N + A L V P + S P+ V G+ C Sbjct: 66 VQPPDSAMYRCLADNPGSSRTGADAELRVLPEPGLPRSLQFLQRPSRVTALLGSDVVLEC 125 Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374 +A+G P P++ W +G I S K ++ V + + ++ D D + C+A Sbjct: 126 SASGYPTPSIQWR-KGEELI----QSWSKKYSLLVGSNLIIRSVTDDDSG----SYSCTA 176 Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFE 434 N + +L+V PP N PSN + C P P + W Sbjct: 177 ANRNQNISATAELSVLV-----PPQFLNYPSNTYAYESTDVELECAVTGNPPPTVRWMKN 231 Query: 435 GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHF 494 GE +I + + + L + L KSD G Y CVA + G LL+ P++P Sbjct: 232 GEEVIPSDYFQMVDGSNLQILGLVKSDEGFYQCVAENAAGSSQAMAQLLLREPVSP---- 287 Query: 495 FRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIG 531 + ++LP P + V+ V LSW + G Sbjct: 288 ---SPGAALPSAPRDLVPVLVSSRFVRLSWRPPEESG 321 Score = 91.9 bits (218), Expect = 1e-16 Identities = 67/210 (31%), Positives = 103/210 (49%), Gaps = 15/210 (7%) Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74 +++P VT L C A G P+P+I+W KG L+ S + + L G +R+ Sbjct: 107 LQRPSRVTALLGSDVVLECSASGYPTPSIQWRKGEELIQSWSKKYSLLVGSNLIIRSV-- 164 Query: 75 RVHSDAGVYWCEATNSYGTARSRNATLHVAVL-REEFRLEPESKQSAQGDTVVLECLPPR 133 D+G Y C A N ++ +AT ++VL +F P + + + V LEC Sbjct: 165 -TDDDSGSYSCTAANRN---QNISATAELSVLVPPQFLNYPSNTYAYESTDVELECAVT- 219 Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES-A 192 G+P P V W KNG+ ++ +VDG NL I ++D G YQC+A NAAG+ ++ A Sbjct: 220 GNPPPTVRWMKNGEEVI--PSDYFQMVDGSNLQILGLVKSDEGFYQCVAENAAGSSQAMA 277 Query: 193 IATLKIHIKP----YLITGPEDVVAQTGSS 218 L+ + P L + P D+V SS Sbjct: 278 QLLLREPVSPSPGAALPSAPRDLVPVLVSS 307 Score = 67.3 bits (157), Expect = 2e-09 Identities = 37/131 (28%), Positives = 61/131 (46%), Gaps = 5/131 (3%) Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751 +++ L K+T+Y ++ + + + T DVP PP NI + ++ + ++ + Sbjct: 493 YKMDGLNKFTEYTVRVLALNRYGPSPATEAAGVTTHSDVPSAPPQNITLEVVLSRSIKVL 552 Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811 W PP QNG+IT Y + +K + N + + T L G YS Q+A Sbjct: 553 WQPPPRSSQNGVITAYKIKYRKTGRRGDKEAIEPNNFWY-----LFTGLEKGSQYSFQVA 607 Query: 812 AETIIGLGPFS 822 A T G GPFS Sbjct: 608 AMTANGTGPFS 618 Score = 45.6 bits (103), Expect = 0.008 Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 4/85 (4%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P + P + L C G+P P +RW K G V+ + ++ L L Sbjct: 195 PQFLNYPSNTYAYESTDVELECAVTGNPPPTVRWMKNGEEVIPSDYFQMVDGSNLQIL-- 252 Query: 72 THGRVHSDAGVYWCEATNSYGTARS 96 G V SD G Y C A N+ G++++ Sbjct: 253 --GLVKSDEGFYQCVAENAAGSSQA 275 Score = 38.3 bits (85), Expect = 1.3 Identities = 40/170 (23%), Positives = 70/170 (41%), Gaps = 18/170 (10%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDD--VPDGPPINIEMFILNTTTVHLK 751 +++L+ Y F +I + G+ S T D VP ++ + L+ T+V + Sbjct: 399 VSNLKPEETYSFRVIAYNDVGPGESSAPLKITTKPDLQVPSRAE-SLRLVALSPTSVQVS 457 Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSM-VAINTTVHQATSLIMTNLTSGVSYSVQI 810 W PP NG I GY ++ W + P+ K V +N+ ++ M L Y+V++ Sbjct: 458 WEPP--SHPNGPILGYRLL--WTESPSGKEQSVEVNSLTYK-----MDGLNKFTEYTVRV 508 Query: 811 AAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETW 860 A G P ++ S D+ S P N + +V + W Sbjct: 509 LALNRYGPSPATEAAGVTTHS-----DVPSAPPQNITLEVVLSRSIKVLW 553 >UniRef50_UPI000065D5B9 Cluster: Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).; n=3; Euteleostomi|Rep: Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2). - Takifugu rubripes Length = 1100 Score = 128 bits (310), Expect = 7e-28 Identities = 123/429 (28%), Positives = 169/429 (39%), Gaps = 38/429 (8%) Query: 32 NCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 +C A G P P RW + R L G L R D G+Y C +NS Sbjct: 31 SCEAQGHPPPFYRWKLNDSFIHPRPGSRYSLVGGNLHISRLNKDE---DVGIYQCLGSNS 87 Query: 91 YGTARSRNATLHVAVLREEFRLEPESK-QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149 +GT SR A+LHVA L E+F+ + + +G VVL C PP S E W N Sbjct: 88 FGTIVSREASLHVAYL-EDFKTHRRNPVRVREGQGVVLLCGPPSHSGELTFKWIFNEYPS 146 Query: 150 LFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGTRESAIA-----TLKI----- 198 D+R + GNL I +D G Y C+ N T+ S L++ Sbjct: 147 FVTQDTRRFVSQKTGNLYIAKVDPSDVGNYTCVVTNTV-TKSSVQGPPTPLVLRVDGVMG 205 Query: 199 HIKPYL-ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD--DG 255 +P + + PE V S+V +C G+P+P + WRR G GR ++ G Sbjct: 206 EYEPKIEVQFPEVVPVAKSSTVKLECFALGNPVPTISWRREGGAS---FGRKVDVNKASG 262 Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315 L + + D G Y C AENS G G L+ Y P + P V + + C Sbjct: 263 VLEIPYFQMEDAGVYECVAENSRGRNLVKGKLSFYAAPQLTEKPQDVQKTIDDTLVWECK 322 Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375 A G+P+P+ W G D+ +T L + D C A Sbjct: 323 ANGKPKPSYRWLKNGEPL----DHMEDRLQVNNGVLNITSLNLADI------GMYQCVAE 372 Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFE 434 N G F +L V + P N QTL + V C +P II+W Sbjct: 373 NRHGRVFTNAELRVVA---IAPDFSQNLLKAQTLARQGGDVLIECKPRMSPRGIISWRKG 429 Query: 435 GEALIQNHR 443 EAL +NHR Sbjct: 430 KEALRENHR 438 Score = 103 bits (247), Expect = 3e-20 Identities = 103/376 (27%), Positives = 148/376 (39%), Gaps = 33/376 (8%) Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA-RQTDAGRYQCIAR 183 VV C +G P P WK N + SR LV GGNL I + D G YQC+ Sbjct: 28 VVFSC-EAQGHPPPFYRWKLNDSFIHPRPGSRYSLV-GGNLHISRLNKDEDVGIYQCLGS 85 Query: 184 NAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRV---GGDPLPDVLWRRSA 239 N+ GT S A+L + +++ + V + G V C G+ ++ Sbjct: 86 NSFGTIVSREASLHVAYLEDFKTHRRNPVRVREGQGVVLLCGPPSHSGELTFKWIFNEYP 145 Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV---------- 289 R G+L + V +D G Y+C N+V S G T Sbjct: 146 SFVTQDTRRFVSQKTGNLYIAKVDPSDVGNYTCVVTNTVTKSSVQGPPTPLVLRVDGVMG 205 Query: 290 -YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348 Y+P P V V + + C A G P PT+ W EG + G D A+ Sbjct: 206 EYEPKIEVQFPEVVPVAKSSTVKLECFALGNPVPTISWRREGGASF---GRKVDVNKASG 262 Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408 V + + + D + C A N G + V+GKL+ + P +T P + Sbjct: 263 VLE-IPYFQMEDAGVYE------CVAENSRGRNLVKGKLSFYA-----APQLTEKPQDVQ 310 Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468 I V+ C A P+P W GE L R N+G L + L+ +D G Y CV Sbjct: 311 KTIDDTLVWECKANGKPKPSYRWLKNGEPLDHMEDRLQVNNGVLNITSLNLADIGMYQCV 370 Query: 469 ASSRHGKYVWSGALLV 484 A +RHG+ + L V Sbjct: 371 AENRHGRVFTNAELRV 386 Score = 74.9 bits (176), Expect = 1e-11 Identities = 65/225 (28%), Positives = 94/225 (41%), Gaps = 11/225 (4%) Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74 ++ P V VA+ L C A G+P P I W + G + A G+ L + Sbjct: 213 VQFPEVVPVAKSSTVKLECFALGNPVPTISWRREGGASFG-RKVDVNKASGV--LEIPYF 269 Query: 75 RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRG 134 ++ DAGVY C A NS G + A + +P+ Q DT+V EC G Sbjct: 270 QM-EDAGVYECVAENSRGRNLVKGKLSFYAA--PQLTEKPQDVQKTIDDTLVWEC-KANG 325 Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194 P+P+ W KNG+ L D R+ V+ G L I D G YQC+A N G + Sbjct: 326 KPKPSYRWLKNGEPLDHMED-RLQ-VNNGVLNITSLNLADIGMYQCVAENRHGRVFTNAE 383 Query: 195 TLKIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 + I P +A+ G V +C+ P + WR+ Sbjct: 384 LRVVAIAPDFSQNLLKAQTLARQGGDVLIECKPRMSPRGIISWRK 428 Score = 60.5 bits (140), Expect = 3e-07 Identities = 44/141 (31%), Positives = 63/141 (44%), Gaps = 8/141 (5%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 AP + E+P DV C+A G P P+ RW K G + R + G L Sbjct: 299 APQLTEKPQDVQKTIDDTLVWECKANGKPKPSYRWLKNGEPLDHMEDRLQVNNG---VLN 355 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEF--RLEPESKQSAQGDTVVLE 128 T + +D G+Y C A N +G + NA L V + +F L + QG V++E Sbjct: 356 ITSLNL-ADIGMYQCVAENRHGRVFT-NAELRVVAIAPDFSQNLLKAQTLARQGGDVLIE 413 Query: 129 CLPPRGSPEPNVYWKKNGQTL 149 C PR SP + W+K + L Sbjct: 414 C-KPRMSPRGIISWRKGKEAL 433 Score = 54.0 bits (124), Expect = 2e-05 Identities = 27/73 (36%), Positives = 39/73 (53%) Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESG 307 +V VLD+GSLR+ NV D+G Y+C A N G S++G L V +P +I ++V G Sbjct: 488 QVTVLDNGSLRISNVTRLDDGLYTCVARNQFGVASSAGSLLVKEPTAITSPAGHLDVTVG 547 Query: 308 NVARFTCTATGRP 320 C + P Sbjct: 548 ESIVLPCQVSHDP 560 Score = 53.2 bits (122), Expect = 4e-05 Identities = 42/143 (29%), Positives = 67/143 (46%), Gaps = 10/143 (6%) Query: 159 LVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT-GS 217 ++D G+L I + + D G Y C+ARN G SA +L + +P IT P + T G Sbjct: 491 VLDNGSLRISNVTRLDDGLYTCVARNQFGVASSA-GSLLVK-EPTAITSPAGHLDVTVGE 548 Query: 218 SVTFQCRVGGDPLPDV--LW---RRSAGGGNMPLGRVKV--LDDGSLRLDNVILADEGEY 270 S+ C+V DP ++ W + GN+ KV G + + N+ G+Y Sbjct: 549 SIVLPCQVSHDPTLELKFTWFFNEQLIHFGNLWAFFEKVGGRSSGDIMIRNIQPKHAGKY 608 Query: 271 SCEAENSVGAVSASGYLTVYDPP 293 +C + V +VS + + V PP Sbjct: 609 TCAVQTKVDSVSIATDVVVRGPP 631 Score = 35.9 bits (79), Expect = 6.7 Identities = 16/42 (38%), Positives = 27/42 (64%) Query: 446 VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 V ++G+L + ++ + D G YTCVA ++ G +G+LLV P Sbjct: 491 VLDNGSLRISNVTRLDDGLYTCVARNQFGVASSAGSLLVKEP 532 >UniRef50_UPI0000E4A418 Cluster: PREDICTED: similar to axonin-1; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to axonin-1 - Strongylocentrotus purpuratus Length = 1053 Score = 128 bits (308), Expect = 1e-27 Identities = 131/496 (26%), Positives = 202/496 (40%), Gaps = 46/496 (9%) Query: 12 PYIIEQPLDV---TVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68 P +++QP + T +L+CRA G W K G + T+ ++ G Sbjct: 23 PILMQQPEETIFDTATNVDSVSLHCRATGDEPITYTWEKDGAPLSQATNARLVITPGQLT 82 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS-AQGDTVVL 127 + + V D G Y C A+N G+ RS A L A + + F S QS G + Sbjct: 83 ITSPERTV--DGGEYVCMASNQVGSVRSLPAELVFAYV-DSFDPSATSTQSLTAGQGGCV 139 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC------I 181 C PP P V W L+ DSR+ ++D G L A +DAG Y+C I Sbjct: 140 TCNPPPHFPGILVNWFHENM-LVDSSDSRIRVMDDGRLCFFYALASDAGAYRCQVKSNVI 198 Query: 182 ARNAAGTRESAIATLKIH-------IKPYLITGPEDVVAQTGSSVTFQCRV-GGDP---L 230 + R S + T+ ++ I+ P DV G V F+C G P + Sbjct: 199 SDGGVEMRVSPLVTVTVNAGSSSSAIRIVQENRPTDVTTIAGEDVKFECFFYGPQPTGQI 258 Query: 231 PDVLW-RRSAGGGNMPLGRVKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYL 287 P V W R S G +P GR VL++G L + V L D G Y C ++ SA L Sbjct: 259 PRVQWVRTSPPGAGLPTGRA-VLEEGGEILSIVGVQLEDAGSYLCYIDDVNSGASAG--L 315 Query: 288 TVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347 V + P+ P + + + A + T W G I R ++ Sbjct: 316 NVAEAPAWVSEPMDAMKDINTMQEWNVEAEEADQYT--WYRNGE---ILTARDRHQFR-- 368 Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407 + + L I+D D+ C A N G + +L+V + PP ++ +++ Sbjct: 369 ---NNLETLIISDLMTTDTA-MYQCFASNDHGMIYSAAQLSVRAF---PPEFLSPMETDK 421 Query: 408 TLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND-GTLVLKDLDKSDSGTYT 466 P+ + C P P + W +G+ + R N+T D LV+ D+ SD GTY Sbjct: 422 PAPLTATVTVVCDVDAAPAPTVTWQHDGQPITDGARYNLTADPPNLVIIDVQMSDGGTYQ 481 Query: 467 CVASSRHGKYVWSGAL 482 C A++ +G G+L Sbjct: 482 CTATNSNGTVTGEGSL 497 Score = 99 bits (238), Expect = 4e-19 Identities = 86/327 (26%), Positives = 138/327 (42%), Gaps = 18/327 (5%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLFF 68 EAP + +P+D + N A + WY+ G +L D H+ L Sbjct: 319 EAPAWVSEPMDAMKDINTMQEWNVEA--EEADQYTWYRNGEILTARDRHQFRNNLETLII 376 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128 + +D +Y C A+N +G S A L V EF E+ + A V Sbjct: 377 ----SDLMTTDTAMYQCFASNDHGMIYSA-AQLSVRAFPPEFLSPMETDKPAPLTATVTV 431 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188 +P P V W+ +GQ + DG D NLVI D + +D G YQC A N+ GT Sbjct: 432 VCDVDAAPAPTVTWQHDGQPIT-DGARYNLTADPPNLVIIDVQMSDGGTYQCTATNSNGT 490 Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG- 247 + +L I + P++ + + G S T +C+ D ++ + G + L Sbjct: 491 -VTGEGSLDIKDATVITGHPDNTLVEVGQSTTLKCKAAHDEYLELTYLWEHNGVEIDLSE 549 Query: 248 --RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305 R ++ D+G+L + + L D GEY+C A + +S L + PP P+ ++VE Sbjct: 550 IERYRMRDNGNLEIVSAQLRDGGEYTCVALTVADSDRSSATLDIAGPPG---PPSGLSVE 606 Query: 306 SGNVARFT--CTATGRPEPTMFWSVEG 330 N+A T P +++EG Sbjct: 607 VENLAANLRWVPGTDNNSPITSFTIEG 633 Score = 74.1 bits (174), Expect = 2e-11 Identities = 90/335 (26%), Positives = 126/335 (37%), Gaps = 22/335 (6%) Query: 7 TSGEAPYIIEQ--PLDVTVARHQPATLNCRA-GGSPS---PAIRWYKGGVLVVS-DTHRS 59 +S A I+++ P DVT + C G P+ P ++W + T R+ Sbjct: 219 SSSSAIRIVQENRPTDVTTIAGEDVKFECFFYGPQPTGQIPRVQWVRTSPPGAGLPTGRA 278 Query: 60 ILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS 119 +L GG + G DAG Y C + A +A L+VA + EP Sbjct: 279 VLEEGGEIL--SIVGVQLEDAGSYLCYIDDVNSGA---SAGLNVAEA-PAWVSEP---MD 329 Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179 A D ++ W +NG+ +L D + L+I D TD YQ Sbjct: 330 AMKDINTMQEWNVEAEEADQYTWYRNGE-ILTARDRHQFRNNLETLIISDLMTTDTAMYQ 388 Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 C A N G SA A L + P P D A ++VT C V P P V W+ Sbjct: 389 CFASNDHGMIYSA-AQLSVRAFPPEFLSPMETDKPAPLTATVTVVCDVDAAPAPTVTWQH 447 Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297 D +L + +V ++D G Y C A NS G V+ G L + D I Sbjct: 448 DGQPITDGARYNLTADPPNLVIIDVQMSDGGTYQCTATNSNGTVTGEGSLDIKDATVITG 507 Query: 298 SPNSVNVESGNVARFTCTATGRP--EPTMFWSVEG 330 P++ VE G C A E T W G Sbjct: 508 HPDNTLVEVGQSTTLKCKAAHDEYLELTYLWEHNG 542 Score = 72.5 bits (170), Expect = 6e-11 Identities = 106/457 (23%), Positives = 166/457 (36%), Gaps = 52/457 (11%) Query: 39 PSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN---SYGTA 94 P + W+ +LV SD+ ++ G L F A + SDAG Y C+ + S G Sbjct: 148 PGILVNWFHENMLVDSSDSRIRVMDDGRLCFFYA----LASDAGAYRCQVKSNVISDGGV 203 Query: 95 RSR---------NATLHVAVLREEFRLEPESKQSAQGDTVVLECL---PPRGSPEPNVYW 142 R NA + +R P + G+ V EC P P V W Sbjct: 204 EMRVSPLVTVTVNAGSSSSAIRIVQENRPTDVTTIAGEDVKFECFFYGPQPTGQIPRVQW 263 Query: 143 KKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201 + R L +GG ++ I + DAG Y C + A A L + Sbjct: 264 VRTSPPGAGLPTGRAVLEEGGEILSIVGVQLEDAGSYLCYIDDV---NSGASAGLNVAEA 320 Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLR--- 258 P ++ P D + + + V + W R+ G + R + +L Sbjct: 321 PAWVSEPMDAMKDINTMQEWN--VEAEEADQYTWYRN---GEILTARDRHQFRNNLETLI 375 Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT--CTA 316 + +++ D Y C A N G + ++ L+V P LSP + + A T C Sbjct: 376 ISDLMTTDTAMYQCFASNDHGMIYSAAQLSVRAFPPEFLSPMETDKPAPLTATVTVVCDV 435 Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376 P PT+ W +G P +Y+ TA + ++ + +D T C+A N Sbjct: 436 DAAPAPTVTWQHDGQ-----PITDGARYNLTADPPNLVIIDVQMSDGG----TYQCTATN 486 Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP--EPIIAWYFE 434 G+ G L D + +IT P N + + C A E W Sbjct: 487 SNGTVTGEGSL-----DIKDATVITGHPDNTLVEVGQSTTLKCKAAHDEYLELTYLWEHN 541 Query: 435 GEA--LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469 G L + R + ++G L + D G YTCVA Sbjct: 542 GVEIDLSEIERYRMRDNGNLEIVSAQLRDGGEYTCVA 578 Score = 36.7 bits (81), Expect = 3.9 Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 2/123 (1%) Query: 700 YTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQL 759 YT+Y + + EG S V + + P P ++ + TT+++ W + Sbjct: 766 YTQYNVRVQAKNDEGEGPFSEWAVIYSYQEAPKTAPTGVKAERASGTTINVSWDAIDEST 825 Query: 760 QNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819 G + GY + W D +N++ ++ TS + L Y+V +AA + G G Sbjct: 826 FEGELMGYKLKY-WSD-DSNEANANTAVSLGVGTSNTIAGLEPSTRYTVMVAAYSGGGNG 883 Query: 820 PFS 822 P S Sbjct: 884 PDS 886 >UniRef50_UPI0000D5796D Cluster: PREDICTED: similar to CG31190-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG31190-PA, isoform A - Tribolium castaneum Length = 1613 Score = 127 bits (307), Expect = 2e-27 Identities = 134/508 (26%), Positives = 204/508 (40%), Gaps = 49/508 (9%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL--PAGGLFFLRATHGRVHS 78 V+ R L C A G+P P W++ + H S P+ + +R Sbjct: 13 VSADRETDIHLTCSAQGNPPPTFNWFREIEGHLQPVHSSARFEPSQDILHIRRLKSE--- 69 Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPE 137 DAG + C+ +N++G R +H+ V + P+ + G++ + C GSP Sbjct: 70 DAGRWTCKVSNNFGEQR---LDIHLTVTAHLSVHVLPQLQVINSGESAIFNCTVS-GSPV 125 Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197 + W +NG+ LL DG+ ++ L+ L + + D G YQC+ RN RESA + + Sbjct: 126 GRILWFRNGEPLLTDGNRKVKLLSPLVLAVYGVTRHDRGMYQCVVRN---DRESAQGSAE 182 Query: 198 IHIK---PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA------GGGNMPLGR 248 + + P L + + G V+ +C G P P W G+ Sbjct: 183 LRLGDTIPELQYTFIEQAMRPGPQVSLRCSASGSPPPQFRWLLDGEPLSDISSGHRYAIS 242 Query: 249 VKVLDDGS----LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304 V +G L + NV + D G YSC A NS+G+ S L +Y PP I S V Sbjct: 243 QYVDQNGDVISHLNISNVRVEDGGLYSCRALNSLGSTEHSARLNIYGPPFIR-SIGPVKA 301 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 +G C +G P ++ W G + D H +G LTI+ D Sbjct: 302 VAGADITLHCPYSGYPIGSVRWERHGQE------LPLDLRHRLGE-EGS--LTISRLDPA 352 Query: 365 DSRNTIVCSAVNYAGSSFVRG-KLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423 C + G R +L V S PPI+ +L A C+ Sbjct: 353 TDSGFYACFVTSRDGEVARREIQLIVNS-----PPILEPFRFPASLQEGGRAQVTCSVTS 407 Query: 424 TPEPI-IAWYFEGE---ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479 PI AWY +GE A +Q R L+ K++ SG+YTCVAS+ + ++ Sbjct: 408 GDMPIHFAWYKDGEHISAALQVEERAAEFYSILIFKEISSKHSGSYTCVASNSAARANYT 467 Query: 480 GALLVDSPINPNIHFFRAADVSSLPGPP 507 L+V + P DVS L G P Sbjct: 468 AQLMV--KVTPQ-WVTEPQDVSVLLGNP 492 Score = 81.4 bits (192), Expect = 1e-13 Identities = 84/309 (27%), Positives = 123/309 (39%), Gaps = 19/309 (6%) Query: 30 TLNCRAGGSPSPAIRWYKGGVLV--VSDTHR----SILPAGG--LFFLRATHGRVHSDAG 81 +L C A GSP P RW G + +S HR + G + L ++ RV D G Sbjct: 208 SLRCSASGSPPPQFRWLLDGEPLSDISSGHRYAISQYVDQNGDVISHLNISNVRVE-DGG 266 Query: 82 VYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVY 141 +Y C A NS G+ +A L++ F ++ G + L C P G P +V Sbjct: 267 LYSCRALNSLGSTE-HSARLNI--YGPPFIRSIGPVKAVAGADITLHC-PYSGYPIGSVR 322 Query: 142 WKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ-TDAGRYQCIARNAAGTRESAIATLKIHI 200 W+++GQ L D R L + G+L I TD+G Y C + G L ++ Sbjct: 323 WERHGQELPLD--LRHRLGEEGSLTISRLDPATDSGFYACFVTSRDGEVARREIQLIVNS 380 Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRRSAGGGNMPLG-RVKVLDDGSLR 258 P L Q G C V +P W + + L + + S+ Sbjct: 381 PPILEPFRFPASLQEGGRAQVTCSVTSGDMPIHFAWYKDGEHISAALQVEERAAEFYSIL 440 Query: 259 LDNVILADE-GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317 + I + G Y+C A NS + + L V P P V+V GN C+A Sbjct: 441 IFKEISSKHSGSYTCVASNSAARANYTAQLMVKVTPQWVTEPQDVSVLLGNPVLVGCSAK 500 Query: 318 GRPEPTMFW 326 G PEP + W Sbjct: 501 GFPEPQITW 509 Score = 70.9 bits (166), Expect = 2e-10 Identities = 56/214 (26%), Positives = 89/214 (41%), Gaps = 10/214 (4%) Query: 30 TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89 TL+C G P ++RW + G + D + G L R +D+G Y C T+ Sbjct: 308 TLHCPYSGYPIGSVRWERHGQELPLDLRHRLGEEGSLTISRLDPA---TDSGFYACFVTS 364 Query: 90 SYGTARSRNATLHV--AVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147 G R L V + E FR P S Q +G + C G + W K+G+ Sbjct: 365 RDGEVARREIQLIVNSPPILEPFRF-PASLQ--EGGRAQVTCSVTSGDMPIHFAWYKDGE 421 Query: 148 TLLFDGDSRMHLVDGGNLVI-QDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT 206 + + +++I ++ +G Y C+A N+A R + A L + + P +T Sbjct: 422 HISAALQVEERAAEFYSILIFKEISSKHSGSYTCVASNSAA-RANYTAQLMVKVTPQWVT 480 Query: 207 GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 P+DV G+ V C G P P + W + G Sbjct: 481 EPQDVSVLLGNPVLVGCSAKGFPEPQITWLKGQG 514 Score = 62.9 bits (146), Expect = 5e-08 Identities = 40/138 (28%), Positives = 65/138 (47%), Gaps = 8/138 (5%) Query: 693 EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKW 752 ++T LRK+T+Y+ + F G S + + T + VP+ PP NI +++ ++ + W Sbjct: 767 QLTGLRKFTRYDINVRAFNSISTGPASPTVIGTTKEGVPEAPPQNIACSQISSQSMKISW 826 Query: 753 SPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH----QATSLIMTNLTSGVSYSV 808 +PP L G+I GY V P V I TT +T + L +YS+ Sbjct: 827 TPPPQTLHGGLIQGYKVYYR----PLPNENVDIPTTGEVKRTSSTETYLHTLFKYTNYSI 882 Query: 809 QIAAETIIGLGPFSQKVY 826 ++ A T G G S +Y Sbjct: 883 KVLAYTGAGDGLMSTPLY 900 Score = 54.0 bits (124), Expect = 2e-05 Identities = 54/222 (24%), Positives = 83/222 (37%), Gaps = 29/222 (13%) Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNV 446 + + + R P I + PIKS + PC A+ P P W + + + + Sbjct: 1001 IVAQATNSRAPSRIASFSQTIKKPIKSKILLPCLAVGNPTPRTRWIHREKPITFSSFYEI 1060 Query: 447 TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGP 506 T++G L + D+S SG YTC A + G + L+V P P Sbjct: 1061 TSEGHLNIHSADQSLSGNYTCSAKNLFGDDNITYTLMVLMP----------------PSA 1104 Query: 507 PTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARR 566 P + + T S+ L W+Q G S I GY + NT + W + Sbjct: 1105 PILEVQFS-TSRSIRLHWTQPED-GGSIIQGYTL-----------NTKHETDDWTSLELS 1151 Query: 567 VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVG 608 + Y + +L G Y + N G PSP+ T G Sbjct: 1152 PEHSVYNLDNLRCGSIYHIYLLAHNRVGNGSPSPILTVNTKG 1193 Score = 52.8 bits (121), Expect = 5e-05 Identities = 35/135 (25%), Positives = 64/135 (47%), Gaps = 7/135 (5%) Query: 639 IEATPIDSKTIKLMW----EILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEI 694 I + I S+++K+ W + L+ ++G +Y+RPL N ++ + + + Sbjct: 812 IACSQISSQSMKISWTPPPQTLHGGLIQGYKVYYRPLPNENVDIPTTGEVKRTSSTETYL 871 Query: 695 TSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSP 754 +L KYT Y ++ + +G S T +D+P GPP +I+ L ++ + W P Sbjct: 872 HTLFKYTNYSIKVLAYTGAGDGLMSTPLYCVTEEDLP-GPPADIKAAALTGESILVSWLP 930 Query: 755 PELQLQNGIITGYNV 769 P NG I+ Y V Sbjct: 931 P--SKPNGRISHYTV 943 Score = 37.9 bits (84), Expect = 1.7 Identities = 31/122 (25%), Positives = 49/122 (40%), Gaps = 6/122 (4%) Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG--DTVVLECLPPRGSPEPNV 140 +W AT S G R R+ S+ + ++L CL G+P P Sbjct: 985 FWISATTSIGEGEPTAIVAQATNSRAPSRIASFSQTIKKPIKSKILLPCLAV-GNPTPRT 1043 Query: 141 YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200 W + + F S + G+L I A Q+ +G Y C A+N G ++ TL + + Sbjct: 1044 RWIHREKPITFS--SFYEITSEGHLNIHSADQSLSGNYTCSAKNLFGD-DNITYTLMVLM 1100 Query: 201 KP 202 P Sbjct: 1101 PP 1102 Score = 36.3 bits (80), Expect = 5.1 Identities = 15/37 (40%), Positives = 19/37 (51%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG 48 P + +P DV+V P + C A G P P I W KG Sbjct: 476 PQWVTEPQDVSVLLGNPVLVGCSAKGFPEPQITWLKG 512 Score = 35.9 bits (79), Expect = 6.7 Identities = 25/104 (24%), Positives = 45/104 (43%), Gaps = 3/104 (2%) Query: 723 VAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSM 782 + +T ++ P P ++ + + + L W+ P + NG + GY +V+W + + Sbjct: 695 IVKTQEEEPSEAPKDVRVESVGPGELFLTWAVPARESWNGELLGY--IVSWNEHGGLPNQ 752 Query: 783 VAINTTVHQATS-LIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825 T AT+ L +T L Y + + A I GP S V Sbjct: 753 TKSLTVKGWATTKLQLTGLRKFTRYDINVRAFNSISTGPASPTV 796 >UniRef50_Q4SIF9 Cluster: Chromosome 5 SCAF14581, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 5 SCAF14581, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 676 Score = 126 bits (304), Expect = 4e-27 Identities = 98/343 (28%), Positives = 142/343 (41%), Gaps = 31/343 (9%) Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77 P VTV R + L+C A G +RW K G V + +L G L+ R Sbjct: 1 PRHVTVTRREAVVLDCHARGEAPVDVRWLKNGARVAQNQRVYLLANGSLYISEVESRRGD 60 Query: 78 -SDAGVYWCEATNSYGTARSRNATLHVAVLREE-----------------FRLEPESKQS 119 SD G+Y C A N +G S+ A L +A L F ++P S Sbjct: 61 KSDEGLYQCLAQNRHGAILSQKARLTIATLCRSAPCFKRGVEKLWARISPFTIQPASLVV 120 Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179 QG C P P + W+ N L + RM ++ G L I ++TDAG Y+ Sbjct: 121 TQGSVARFSC-KITAHPPPIITWEFNRVPLPLITE-RMTVLPSGVLQIYGVQRTDAGSYR 178 Query: 180 CIARNAAGTRESAIATLKIHI--------KPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231 C A N R SA L + +P +I GP+++ + +C G+P P Sbjct: 179 CTATNIGSRRRSAEGFLTVTPAPNPPLPQRPRIIAGPQNISVSLHHNAILECMATGNPRP 238 Query: 232 DVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAEN--SVGAVSASGYLTV 289 + W R A ++ + KVL +G+L + +V G Y C A + A+ +TV Sbjct: 239 IISWSR-ADSKSIDVYNTKVLGNGNLIITDVKPQHGGVYVCRATTPGTRNYTVAAANITV 297 Query: 290 YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332 PPS+ P S+ ARF C A G P P + W G + Sbjct: 298 LAPPSLVEWPESLTRPRAGTARFVCQAEGVPAPQITWLKNGEK 340 Score = 101 bits (242), Expect = 1e-19 Identities = 100/355 (28%), Positives = 147/355 (41%), Gaps = 52/355 (14%) Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR-----QTDAGR 177 + VVL+C RG +V W KNG + + R++L+ G+L I + ++D G Sbjct: 10 EAVVLDC-HARGEAPVDVRWLKNGARVA--QNQRVYLLANGSLYISEVESRRGDKSDEGL 66 Query: 178 YQCIARNAAGTRESAIATLKI-------------------HIKPYLITGPEDVVAQTGSS 218 YQC+A+N G S A L I I P+ I P +V GS Sbjct: 67 YQCLAQNRHGAILSQKARLTIATLCRSAPCFKRGVEKLWARISPFTIQ-PASLVVTQGSV 125 Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSV 278 F C++ P P + W + + R+ VL G L++ V D G Y C A N + Sbjct: 126 ARFSCKITAHPPPIITWEFNRVPLPLITERMTVLPSGVLQIYGVQRTDAGSYRCTATN-I 184 Query: 279 GAV--SASGYLTVYDPPS--------INLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328 G+ SA G+LTV P+ I P +++V + A C ATG P P + WS Sbjct: 185 GSRRRSAEGFLTVTPAPNPPLPQRPRIIAGPQNISVSLHHNAILECMATGNPRPIISWSR 244 Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT 388 +++I D Y+ + +G ++T D K VC A ++ Sbjct: 245 ADSKSI-------DVYNTKVLGNGNLIIT--DV-KPQHGGVYVCRATTPGTRNYTVAAAN 294 Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR 443 +T PP + P + T P A F C A P P I W GE + N R Sbjct: 295 ITV---LAPPSLVEWPESLTRPRAGTARFVCQAEGVPAPQITWLKNGEKVHSNGR 346 Score = 84.6 bits (200), Expect = 1e-14 Identities = 69/253 (27%), Positives = 108/253 (42%), Gaps = 20/253 (7%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFFL 69 +P+ I QP + V + A +C+ P P I W V + T R ++LP+G L Sbjct: 109 SPFTI-QPASLVVTQGSVARFSCKITAHPPPIITWEFNRVPLPLITERMTVLPSGVL--- 164 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVL-------REEFRLEPESKQSAQG 122 +G +DAG Y C ATN RS L V R P++ + Sbjct: 165 -QIYGVQRTDAGSYRCTATNIGSRRRSAEGFLTVTPAPNPPLPQRPRIIAGPQNISVSLH 223 Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182 +LEC+ G+P P + W + + +++ ++ GNL+I D + G Y C A Sbjct: 224 HNAILECM-ATGNPRPIISWSRADSKSIDVYNTK--VLGNGNLIITDVKPQHGGVYVCRA 280 Query: 183 RNAAGTRESAIATLKIHI--KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 GTR +A I + P L+ PE + + F C+ G P P + W ++ G Sbjct: 281 -TTPGTRNYTVAAANITVLAPPSLVEWPESLTRPRAGTARFVCQAEGVPAPQITWLKN-G 338 Query: 241 GGNMPLGRVKVLD 253 GR+K+ D Sbjct: 339 EKVHSNGRIKMYD 351 Score = 82.2 bits (194), Expect = 8e-14 Identities = 83/292 (28%), Positives = 120/292 (41%), Gaps = 38/292 (13%) Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL--- 264 P V +V C G+ DV W ++ G RV +L +GSL + V Sbjct: 1 PRHVTVTRREAVVLDCHARGEAPVDVRWLKN-GARVAQNQRVYLLANGSLYISEVESRRG 59 Query: 265 --ADEGEYSCEAENSVGAV-SASGYLTVY----DPPSIN--------------LSPNSVN 303 +DEG Y C A+N GA+ S LT+ P + P S+ Sbjct: 60 DKSDEGLYQCLAQNRHGAILSQKARLTIATLCRSAPCFKRGVEKLWARISPFTIQPASLV 119 Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363 V G+VARF+C T P P + W E NR + P ++ T + GV L I + Sbjct: 120 VTQGSVARFSCKITAHPPPIITW--EFNR-VPLPLITE---RMTVLPSGV--LQIYGVQR 171 Query: 364 NDSRNTIVCSAVNYAGSS-FVRGKLTVTSDDDRP---PPIITNGPSNQTLPIKSMAVFPC 419 D+ + C+A N G LTVT + P P I GP N ++ + A+ C Sbjct: 172 TDA-GSYRCTATNIGSRRRSAEGFLTVTPAPNPPLPQRPRIIAGPQNISVSLHHNAILEC 230 Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471 A P PII+W I + V +G L++ D+ G Y C A++ Sbjct: 231 MATGNPRPIISWSRADSKSIDVYNTKVLGNGNLIITDVKPQHGGVYVCRATT 282 Score = 65.3 bits (152), Expect = 1e-08 Identities = 46/152 (30%), Positives = 68/152 (44%), Gaps = 11/152 (7%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF- 68 + P II P +++V+ H A L C A G+P P I W + + + +L G L Sbjct: 207 QRPRIIAGPQNISVSLHHNAILECMATGNPRPIISWSRADSKSIDVYNTKVLGNGNLIIT 266 Query: 69 -LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVV 126 ++ HG GVY C AT GT A ++ VL +E PES + T Sbjct: 267 DVKPQHG------GVYVCRATTP-GTRNYTVAAANITVLAPPSLVEWPESLTRPRAGTAR 319 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH 158 C G P P + W KNG+ + +G +M+ Sbjct: 320 FVC-QAEGVPAPQITWLKNGEKVHSNGRIKMY 350 Score = 50.0 bits (114), Expect = 4e-04 Identities = 45/206 (21%), Positives = 87/206 (42%), Gaps = 9/206 (4%) Query: 639 IEATPIDSKTIKLMWE--ILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITS 696 ++A + S I L WE + N + +++ + + E E + ++ ND + + I Sbjct: 433 VQADTVSSSAILLAWERPLYNSDKVIAYSVHYMKAEGLNNE-EYQVVI-GNDTTRYIIDD 490 Query: 697 LRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPE 756 L Y F+++ + + S+ T +DVP P + + + T + + W P Sbjct: 491 LEPARNYTFYIVAYMALGASRMSDHVFQCTFEDVPLRAP-ELSLTSHSPTDIQVSWQPLP 549 Query: 757 LQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETII 816 +L G ++ Y++ D A S V ++ + T ++ NL +Y ++IAA T + Sbjct: 550 EKLSRGRVSAYSLSYRSGDGGA-VSQVELS---GEQTQHLLENLQPDTTYLLRIAAATSV 605 Query: 817 GLGPFSQKVYFNIDSRSVGLDLLSRY 842 G G S S D +Y Sbjct: 606 GWGEQSVWTSHRTPKASTARDPRKKY 631 Score = 41.5 bits (93), Expect = 0.14 Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 5/76 (6%) Query: 404 PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL-----D 458 P + T+ + V C A + W G + QN R + +G+L + ++ D Sbjct: 1 PRHVTVTRREAVVLDCHARGEAPVDVRWLKNGARVAQNQRVYLLANGSLYISEVESRRGD 60 Query: 459 KSDSGTYTCVASSRHG 474 KSD G Y C+A +RHG Sbjct: 61 KSDEGLYQCLAQNRHG 76 >UniRef50_Q8TDY8 Cluster: Neighbor of punc e11 precursor; n=23; Theria|Rep: Neighbor of punc e11 precursor - Homo sapiens (Human) Length = 1250 Score = 126 bits (304), Expect = 4e-27 Identities = 102/338 (30%), Positives = 151/338 (44%), Gaps = 32/338 (9%) Query: 18 PLDVTVARHQPATLNCRAGGS---PSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR--AT 72 PL V + Q A LNC G + P + W K G ++ H +LP G L+ + A Sbjct: 42 PLQVILGPEQAAVLNCSLGAAAAGPPTRVTWSKDGDTLLEHDHLHLLPNGSLWLSQPLAP 101 Query: 73 HGRVHS--DA-----GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 +G S +A G Y C A G S+ A + +A L + F L PES+ + T Sbjct: 102 NGSDESVPEAVGVIEGNYSCLAHGPLGVLASQTAVVKLATLAD-FSLHPESQTVEENGTA 160 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 EC G P P + W+K+ TL + R+ ++ G L I D +++DAG Y+C+A N+ Sbjct: 161 RFEC-HIEGLPAPIITWEKDQVTL--PEEPRLIVLPNGVLQILDVQESDAGPYRCVATNS 217 Query: 186 AGTRESAIATLKIHIKPYL----------ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235 A S A L + + L + PE+ +G SV +C DP P V W Sbjct: 218 ARQHFSQEALLSVAHRGSLASTRGQDVVIVAAPENTTVVSGQSVVMECVASADPTPFVSW 277 Query: 236 RRSAGGGNMPLGR-VKVLDDGSLRLDNVILADEGEYSCEAEN--SVGAVSASGYLTVYDP 292 R G P+ V VL +L + N G Y C A + +A+ L V Sbjct: 278 VRQDG---KPISTDVIVLGRTNLLIANAQPWHSGVYVCRANKPRTRDFATAAAELRVLAA 334 Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330 P+I +P +++ + ARF C A+G P P + W G Sbjct: 335 PAITQAPEALSRTRASTARFVCRASGEPRPALRWLHNG 372 Score = 112 bits (269), Expect = 6e-23 Identities = 95/298 (31%), Positives = 135/298 (45%), Gaps = 24/298 (8%) Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77 P TV + A C G P+P I W K V + + +LP G L L Sbjct: 149 PESQTVEENGTARFECHIEGLPAPIITWEKDQVTLPEEPRLIVLPNGVLQILDVQE---- 204 Query: 78 SDAGVYWCEATNSYGTARSRNATLHVA-------VLREEFRL--EPESKQSAQGDTVVLE 128 SDAG Y C ATNS S+ A L VA ++ + PE+ G +VV+E Sbjct: 205 SDAGPYRCVATNSARQHFSQEALLSVAHRGSLASTRGQDVVIVAAPENTTVVSGQSVVME 264 Query: 129 CLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 C+ P P V W +++G+ + D + ++ NL+I +A+ +G Y C A N Sbjct: 265 CVAS-ADPTPFVSWVRQDGKPISTD----VIVLGRTNLLIANAQPWHSGVYVCRA-NKPR 318 Query: 188 TRE--SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 TR+ +A A L++ P + PE + S+ F CR G+P P + W + G P Sbjct: 319 TRDFATAAAELRVLAAPAITQAPEALSRTRASTARFVCRASGEPRPALRWLHN-GAPLRP 377 Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302 GRVKV G SL + + L D G Y C AENS G A+ L V + +P V Sbjct: 378 NGRVKVQGGGGSLVITQIGLQDAGYYQCVAENSAGMACAAASLAVVVREGLPSAPTRV 435 Score = 86.6 bits (205), Expect = 4e-15 Identities = 108/431 (25%), Positives = 162/431 (37%), Gaps = 58/431 (13%) Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ--------DARQTDA-----GRYQCIA 182 P V W K+G TLL +HL+ G+L + D +A G Y C+A Sbjct: 66 PPTRVTWSKDGDTLL--EHDHLHLLPNGSLWLSQPLAPNGSDESVPEAVGVIEGNYSCLA 123 Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242 G S A +K+ PE + + F+C + G P P + W + Sbjct: 124 HGPLGVLASQTAVVKLATLADFSLHPESQTVEENGTARFECHIEGLPAPIITWEKDQ--V 181 Query: 243 NMP-LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPS------ 294 +P R+ VL +G L++ +V +D G Y C A NS S L+V S Sbjct: 182 TLPEEPRLIVLPNGVLQILDVQESDAGPYRCVATNSARQHFSQEALLSVAHRGSLASTRG 241 Query: 295 ----INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350 I +P + V SG C A+ P P + W + + I S D + Sbjct: 242 QDVVIVAAPENTTVVSGQSVVMECVASADPTPFVSWVRQDGKPI-----STD-----VIV 291 Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410 G T L I + S VC A F + P IT P + Sbjct: 292 LGRTNLLIANAQPWHS-GVYVCRANKPRTRDFATAAAELRV---LAAPAITQAPEALSRT 347 Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT-NDGTLVLKDLDKSDSGTYTCVA 469 S A F C A P P + W G L N R V G+LV+ + D+G Y CVA Sbjct: 348 RASTARFVCRASGEPRPALRWLHNGAPLRPNGRVKVQGGGGSLVITQIGLQDAGYYQCVA 407 Query: 470 SSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529 + G + +L V LP PT+ ++ ++V ++W + + Sbjct: 408 ENSAGMACAAASLAV-------------VVREGLPSAPTRVTATPLSSSAVLVAW-ERPE 453 Query: 530 IGSSSILGYQV 540 + S I+G+ + Sbjct: 454 MHSEQIIGFSL 464 Score = 73.7 bits (173), Expect = 3e-11 Identities = 64/213 (30%), Positives = 90/213 (42%), Gaps = 10/213 (4%) Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66 T G+ I+ P + TV Q + C A P+P + W + +S ++ G Sbjct: 239 TRGQDVVIVAAPENTTVVSGQSVVMECVASADPTPFVSWVRQDGKPIST---DVIVLGRT 295 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTV 125 L A HS GVY C A N T A + VL + PE+ + T Sbjct: 296 NLLIANAQPWHS--GVYVCRA-NKPRTRDFATAAAELRVLAAPAITQAPEALSRTRASTA 352 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 C G P P + W NG L +G ++ GG+LVI DAG YQC+A N+ Sbjct: 353 RFVCRAS-GEPRPALRWLHNGAPLRPNGRVKVQ-GGGGSLVITQIGLQDAGYYQCVAENS 410 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSS 218 AG A A+L + ++ L + P V A SS Sbjct: 411 AG-MACAAASLAVVVREGLPSAPTRVTATPLSS 442 Score = 67.3 bits (157), Expect = 2e-09 Identities = 50/199 (25%), Positives = 89/199 (44%), Gaps = 17/199 (8%) Query: 639 IEATPIDSKTIKLMWEILNFY--YLEGLFIYF---RPLDNITIEYEMKTILHSNDVSGFE 693 + ATP+ S + + WE + + G +++ R +DN+ EY+ +ND + + Sbjct: 435 VTATPLSSSAVLVAWERPEMHSEQIIGFSLHYQKARGMDNV--EYQFAV---NNDTTELQ 489 Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753 + L T YEF+++ + + + S + TLDDVP P + + N + + + W Sbjct: 490 VRDLEPNTDYEFYVVAYSQLGASRTSTPALVHTLDDVPSAAP-QLSLSSPNPSDIRVAWL 548 Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH-QATSLIMTNLTSGVSYSVQIAA 812 P L NG + Y + + K +T V T L++ +L Y V+I+A Sbjct: 549 PLPPSLSNGQVVKYKI-----EYGLGKEDQIFSTEVRGNETQLMLNSLQPNKVYRVRISA 603 Query: 813 ETIIGLGPFSQKVYFNIDS 831 T G G SQ ++ S Sbjct: 604 GTAAGFGAPSQWMHHRTPS 622 Score = 52.0 bits (119), Expect = 1e-04 Identities = 38/130 (29%), Positives = 56/130 (43%), Gaps = 3/130 (2%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753 I L+ +TKYEF + +G + TL D P PP ++ + L +TV L W Sbjct: 810 IGGLKPFTKYEFAVQSHGVDMDGPFGSVVERSTLPDRPSTPPSDLRLSPLTPSTVRLHWC 869 Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAE 813 PP NG I Y ++ + + TT S + L S Y ++ A Sbjct: 870 PP--TEPNGEIVEYLILYSSNHTQPEHQWTLL-TTQGNIFSAEVHGLESDTRYFFKMGAR 926 Query: 814 TIIGLGPFSQ 823 T +G GPFS+ Sbjct: 927 TEVGPGPFSR 936 >UniRef50_UPI00015B613E Cluster: PREDICTED: similar to frazzled protein; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to frazzled protein - Nasonia vitripennis Length = 1478 Score = 125 bits (302), Expect = 6e-27 Identities = 87/298 (29%), Positives = 141/298 (47%), Gaps = 18/298 (6%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFLR 70 P +P D V Q A L+C+ S I+W K L++ ++ +ILP+G L Sbjct: 133 PGFDREPQDTMVYPGQIAYLSCKLATSDQVNIQWLKDEQPLLLDESRMTILPSGALEIDE 192 Query: 71 ATHGRVHSDAGVYWCEATN--SYGTARSRNATLHVAVLREE-----FRLEPESKQSAQGD 123 G D G Y C A+ Y + L + + E F +P ++ + + Sbjct: 193 VLPG----DVGSYRCNASGFGQYRLSTKAQLALQTSDIGEGESMPVFVAKPFNQVAIEKS 248 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182 T+ LEC G+P+P VYW K+G ++ L DSR V +L+I+D + D G YQC A Sbjct: 249 TITLECAA-NGNPKPEVYWLKDGTSIDLASLDSRYQTVAASSLMIKDVTEEDNGSYQCRA 307 Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242 +N T + A+A + + + P I P+D A + F+C + G P P + W ++ G Sbjct: 308 KNDIDTLD-AVAEVVVQVPPRFIKRPQDKEASEHQELEFECEIYGKPPPLITWLKN--GE 364 Query: 243 NMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299 + L L +G +L+++ ++ D G + C N G+V AS LT++ P P Sbjct: 365 VIKLSNYWQLTNGYNLKINGLLNIDAGIFQCMGTNPAGSVQASARLTIHQPKKERKGP 422 Score = 109 bits (262), Expect = 5e-22 Identities = 92/336 (27%), Positives = 137/336 (40%), Gaps = 29/336 (8%) Query: 17 QPLDVTVARHQPATLNCRA------GG--SPSPAIRWY-KGG--VLVVSDTHRSILPAGG 65 +P D+ + + A L+C A GG P I W + G + + D +RS L G Sbjct: 35 EPEDLVLELGKSARLDCEAKIEATPGGLLQDLPVITWRTEDGQPINFIGDKYRSQLENGS 94 Query: 66 LFFLRATHGRVHSDAGVYWCEAT-NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124 L+ A + G Y C A+ + G SR A + +A L F EP+ G Sbjct: 95 LYISAANQESI----GSYQCVASIENVGAIASRTAVVKLASL-PGFDREPQDTMVYPGQI 149 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 L C S + N+ W K+ Q LL D +SRM ++ G L I + D G Y+C A Sbjct: 150 AYLSCKLAT-SDQVNIQWLKDEQPLLLD-ESRMTILPSGALEIDEVLPGDVGSYRCNASG 207 Query: 185 AAGTRESAIATLKIHIK--------PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 R S A L + P + P + VA S++T +C G+P P+V W Sbjct: 208 FGQYRLSTKAQLALQTSDIGEGESMPVFVAKPFNQVAIEKSTITLECAANGNPKPEVYWL 267 Query: 237 RSAGGGNMPL--GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294 + ++ R + + SL + +V D G Y C A+N + + A + V PP Sbjct: 268 KDGTSIDLASLDSRYQTVAASSLMIKDVTEEDNGSYQCRAKNDIDTLDAVAEVVVQVPPR 327 Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330 P F C G+P P + W G Sbjct: 328 FIKRPQDKEASEHQELEFECEIYGKPPPLITWLKNG 363 Score = 103 bits (246), Expect = 4e-20 Identities = 95/398 (23%), Positives = 154/398 (38%), Gaps = 32/398 (8%) Query: 109 EFRLEPESKQSAQGDTVVLEC-----LPPRGSPE--PNVYWK-KNGQTLLFDGDSRMHLV 160 +F EPE G + L+C P G + P + W+ ++GQ + F GD + Sbjct: 31 QFSHEPEDLVLELGKSARLDCEAKIEATPGGLLQDLPVITWRTEDGQPINFIGDKYRSQL 90 Query: 161 DGGNLVIQDARQTDAGRYQCIAR-NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSV 219 + G+L I A Q G YQC+A G S A +K+ P P+D + G Sbjct: 91 ENGSLYISAANQESIGSYQCVASIENVGAIASRTAVVKLASLPGFDREPQDTMVYPGQIA 150 Query: 220 TFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAEN-SV 278 C++ ++ W + + R+ +L G+L +D V+ D G Y C A Sbjct: 151 YLSCKLATSDQVNIQWLKDEQPLLLDESRMTILPSGALEIDEVLPGDVGSYRCNASGFGQ 210 Query: 279 GAVSASGYLTVYDP--------PSINLSP-NSVNVESGNVARFTCTATGRPEPTMFWSVE 329 +S L + P P N V +E + C A G P+P ++W + Sbjct: 211 YRLSTKAQLALQTSDIGEGESMPVFVAKPFNQVAIEKSTIT-LECAANGNPKPEVYWLKD 269 Query: 330 GNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389 G T I +Y A + L I D + D+ + C A N + ++ V Sbjct: 270 G--TSIDLASLDSRYQTVAA----SSLMIKDVTEEDN-GSYQCRAKNDIDTLDAVAEVVV 322 Query: 390 TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND 449 + PP P ++ F C P P+I W GE + ++ +TN Sbjct: 323 -----QVPPRFIKRPQDKEASEHQELEFECEIYGKPPPLITWLKNGEVIKLSNYWQLTNG 377 Query: 450 GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 L + L D+G + C+ ++ G S L + P Sbjct: 378 YNLKINGLLNIDAGIFQCMGTNPAGSVQASARLTIHQP 415 Score = 79.0 bits (186), Expect = 7e-13 Identities = 59/199 (29%), Positives = 85/199 (42%), Gaps = 16/199 (8%) Query: 6 VTSGEA-PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSDTHRSIL 61 + GE+ P + +P + TL C A G+P P + W K G L D+ + Sbjct: 226 IGEGESMPVFVAKPFNQVAIEKSTITLECAANGNPKPEVYWLKDGTSIDLASLDSRYQTV 285 Query: 62 PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV-LREEFRLEPESKQSA 120 A L T D G Y C A N T +A V V + F P+ K+++ Sbjct: 286 AASSLMIKDVT----EEDNGSYQCRAKNDIDTL---DAVAEVVVQVPPRFIKRPQDKEAS 338 Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180 + + EC G P P + W KNG+ + + L +G NL I DAG +QC Sbjct: 339 EHQELEFEC-EIYGKPPPLITWLKNGEVIKL--SNYWQLTNGYNLKINGLLNIDAGIFQC 395 Query: 181 IARNAAGTRESAIATLKIH 199 + N AG+ + A A L IH Sbjct: 396 MGTNPAGSVQ-ASARLTIH 413 Score = 70.1 bits (164), Expect = 3e-10 Identities = 63/237 (26%), Positives = 103/237 (43%), Gaps = 17/237 (7%) Query: 588 RTENSHGLSGPSPVSDSV--TVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPID 645 R E + +SG P + + V + SN L + V T + H + L P Sbjct: 580 REETTVTISGLQPGTTYLFRAVANVSNVLSASSKVLELTTESEPNVPSHPLNL-RGWPTS 638 Query: 646 SKTIKLMWE--ILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKY 703 S++I L WE + G I + D YE +N + +E+T L+ Y +Y Sbjct: 639 SQSIMLSWEEPTTTNGRISGYLITYAEGD-----YEELNRNTTN--TSYELTGLKPYREY 691 Query: 704 EFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGI 763 ++ G ++ +T DVP PP N+ + T++ ++W PP + QNGI Sbjct: 692 NIWVQAINDNGPGASTSEIRVRTFGDVPSNPP-NVTIEAGGATSIVIRWEPPS-EGQNGI 749 Query: 764 ITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGP 820 ITGY + D + S++ TT A ++ L +SY V++ A + G GP Sbjct: 750 ITGYKIRYRPTDRRIHSSLI---TTDGNARYYVLNRLQKNISYQVRVCAFNVNGTGP 803 Score = 49.6 bits (113), Expect = 5e-04 Identities = 32/114 (28%), Positives = 52/114 (45%), Gaps = 6/114 (5%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I++P D + HQ C G P P I W K G ++ + + L Sbjct: 326 PRFIKRPQDKEASEHQELEFECEIYGKPPPLITWLKNGEVIKLSNYWQLTNGYNL----K 381 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 +G ++ DAG++ C TN G+ ++ +A L + ++E R P +SA G V Sbjct: 382 INGLLNIDAGIFQCMGTNPAGSVQA-SARLTIHQPKKE-RKGPGRHRSANGKPV 433 Score = 43.2 bits (97), Expect = 0.044 Identities = 39/145 (26%), Positives = 65/145 (44%), Gaps = 7/145 (4%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNT--TTVHLK 751 I L+ T+YEF + + E S + +TL+ P PP ++ + ++ +V L+ Sbjct: 986 IHDLKPNTEYEFTVKVVKGRRESPWSMVVMNKTLEAKPSSPPRDLTVQSIDEYPKSVLLR 1045 Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIM-TNLTSGVSYSVQI 810 W PP+L NG I GY ++ D ++ V T ++ L +Y +I Sbjct: 1046 WLPPKLS--NGDINGY-IIRYTTDNNKDERDWKTEAFVGDKTEFVLPAELQPSTTYYFKI 1102 Query: 811 AAETIIGLGPFSQKV-YFNIDSRSV 834 A G GPFS V Y + S+ + Sbjct: 1103 GARNAKGYGPFSSTVPYRTLKSKHI 1127 >UniRef50_Q9VN14 Cluster: Contactin precursor; n=4; Endopterygota|Rep: Contactin precursor - Drosophila melanogaster (Fruit fly) Length = 1390 Score = 125 bits (302), Expect = 6e-27 Identities = 116/489 (23%), Positives = 193/489 (39%), Gaps = 42/489 (8%) Query: 12 PYIIEQPLDVT--VARHQ---PATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP-AGG 65 PY ++QP D T V +++ TL+C A G P+P+ WY+ + ++ I P A Sbjct: 362 PYFVKQPNDTTFDVNKNRLINDVTLSCLANGYPTPSYTWYREVYVDDRLEYQKIDPLAQD 421 Query: 66 LFFLRATHGRVHS-----DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA 120 + + + ++ D G Y C A N +G RS +A L+ + E F L+ ++ S Sbjct: 422 RYTISGGNLIIYEPKQALDQGAYHCVAENKFGRIRSESAHLNFGFIME-FNLKRSAETSE 480 Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180 + C PP+ P+ YW ++ + D R+ + G L D Y C Sbjct: 481 MNWGKSIFCDPPQHYPDVRYYWARDYFPNFVEEDQRVFVSRDGALYFSFIETVDRANYSC 540 Query: 181 IARNAAGT--RESAIATLKI----HIKPYLITG------PEDVVAQTGSSVTFQCRVGGD 228 + R L++ + + + PE VA G + +C G Sbjct: 541 TVQTLVSDTGRNGPFFPLRVTPNSNYQALIFANTFPKVFPEAPVA--GDEIRLECMAFGY 598 Query: 229 PLPDVLWRRSAGGGNMPLGR-VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGY 286 P+P W R +PL R ++ G L + N D GEYSC N + S Y Sbjct: 599 PIPSYNWTRQG----LPLQRNAYTINYGRVLIIQNATTNDNGEYSCTITNPRKTLMKSIY 654 Query: 287 LTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHA 346 + + P + + + + F C A P+ W R + ++RD+Y Sbjct: 655 INIQMRPQFTIPLKDMIKDYNSDVTFICEAFAIPDANYTWYKNAER-LDPANINRDRY-- 711 Query: 347 TAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN 406 + D V + + DK+D+ C A N +SF +L V S P + + Sbjct: 712 -IIQDNVLTIKFLEKDKDDAMYQ--CGAQNQLKTSFSSAQLRVLS---MKPSFKKHPLES 765 Query: 407 QTLPI-KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465 + + C P P W +G+ + R + GTL + + D G Y Sbjct: 766 EVYAVYNGNTTIVCDPEAAPRPKFQWKKDGQVIGSGGHRRILPSGTLTISPTSRDDEGIY 825 Query: 466 TCVASSRHG 474 TC+AS++ G Sbjct: 826 TCIASNQAG 834 Score = 91.5 bits (217), Expect = 1e-16 Identities = 66/234 (28%), Positives = 111/234 (47%), Gaps = 17/234 (7%) Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSA--QGDTVVLECLPPRGS 135 D +Y C A N T+ S +A L V ++ F+ P ES+ A G+T ++ C P + Sbjct: 728 DDAMYQCGAQNQLKTSFS-SAQLRVLSMKPSFKKHPLESEVYAVYNGNTTIV-C-DPEAA 784 Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195 P P WKK+GQ + G R ++ G L I + D G Y CIA N AGT ES Sbjct: 785 PRPKFQWKKDGQVIGSGGHRR--ILPSGTLTISPTSRDDEGIYTCIASNQAGTDESHARV 842 Query: 196 LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV--LWRRSA---GGGNMPLGRVK 250 + + ++ T P+ +V++ + C D L D+ +W+ + + GR+ Sbjct: 843 IVLQEIRFIETPPQRIVSKEHDLIFLHCEAAFDELLDIAYVWKHNGEVLKNNHDGTGRI- 901 Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304 ++D L + N + D G+Y C +++V +S+ +++ P +P V V Sbjct: 902 IVDWNRLTVHNTSMRDAGDYECVVKSAVNEISSKTSVSIEGAPG---APGGVQV 952 Score = 82.6 bits (195), Expect = 6e-14 Identities = 156/719 (21%), Positives = 261/719 (36%), Gaps = 74/719 (10%) Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQC 180 GD + LEC+ G P P+ W + G L + ++ G L+IQ+A D G Y C Sbjct: 586 GDEIRLECMA-FGYPIPSYNWTRQGLPL----QRNAYTINYGRVLIIQNATTNDNGEYSC 640 Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA- 239 N T +I + I ++P +D++ S VTF C P + W ++A Sbjct: 641 TITNPRKTLMKSIY-INIQMRPQFTIPLKDMIKDYNSDVTFICEAFAIPDANYTWYKNAE 699 Query: 240 --GGGNMPLGRVKVLDDGSLRLDNVIL-ADEGEYSCEAENSVGAVSASGYLTVYD-PPSI 295 N+ R ++ D L + + D+ Y C A+N + +S L V PS Sbjct: 700 RLDPANINRDRY-IIQDNVLTIKFLEKDKDDAMYQCGAQNQLKTSFSSAQLRVLSMKPSF 758 Query: 296 NLSP---NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352 P V +GN C P P W +G +I G H + G Sbjct: 759 KKHPLESEVYAVYNGNTT-IVCDPEAAPRPKFQWKKDGQ--VIGSG-----GHRRILPSG 810 Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412 LTI+ T ++D C A N AG+ ++ V + I P Sbjct: 811 --TLTISPTSRDD-EGIYTCIASNQAGTDESHARVIVLQE----IRFIETPPQRIVSKEH 863 Query: 413 SMAVFPCTAICTPEPIIA--WYFEGEALIQNH---RRNVTNDGTLVLKDLDKSDSGTYTC 467 + C A IA W GE L NH R + + L + + D+G Y C Sbjct: 864 DLIFLHCEAAFDELLDIAYVWKHNGEVLKNNHDGTGRIIVDWNRLTVHNTSMRDAGDYEC 923 Query: 468 VASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527 V V S +N I + + PG P ++ T + W Sbjct: 924 V---------------VKSAVN-EISSKTSVSIEGAPGAPGGVQVIQISKTKAIIEWVDG 967 Query: 528 NKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIV 587 + G +I Y + + + N + + V Q VV +L P Y F V Sbjct: 968 SHNG-RAIRYYNILGRTNWNRTWVNVSTHVQAREVDRYTSRQQAEVV-NLTPWSAYEFSV 1025 Query: 588 RTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSK 647 N G+ PS S + +D + + + D + P + Sbjct: 1026 TAVNDLGIGTPSAPSPIYSTYEDKPYI-----APRNVGGGGGKIGDLTITWDPLLPQEQH 1080 Query: 648 TIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFL 707 + + +++ F+ L+G + D I + M + + ++ + YT+YE + Sbjct: 1081 SHGIHYKV--FWKLKGAIEW--ASDEIKKQDHMGVAVVNIPLNNY-------YTEYEVKV 1129 Query: 708 IPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQN--GIIT 765 +G S V + +D+P P N+T ++ W P ++ +N G + Sbjct: 1130 QAINSVGKGPESEIAVIHSAEDMPQVAPQKPIALAYNSTCFNVTWQPIDMSRENIRGKLI 1189 Query: 766 GYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQK 824 G+ + W + V + + +LI+ L Y V++ A G GP S++ Sbjct: 1190 GHRLKY-WKTTHQEEDSVYYLSRTTRNWALIV-GLQPDTYYFVKVMAYNAAGEGPESER 1246 Score = 73.3 bits (172), Expect = 4e-11 Identities = 52/161 (32%), Positives = 75/161 (46%), Gaps = 13/161 (8%) Query: 30 TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89 T+ C +P P +W K G ++ S HR ILP+G L + D G+Y C A+N Sbjct: 776 TIVCDPEAAPRPKFQWKKDGQVIGSGGHRRILPSGTLTISPTS----RDDEGIYTCIASN 831 Query: 90 SYGTARSRNATLHVAVLREEFRLE--PESKQSAQGDTVVLECLPPRGSPEPNVY-WKKNG 146 GT S V VL+E +E P+ S + D + L C Y WK NG Sbjct: 832 QAGTDESH---ARVIVLQEIRFIETPPQRIVSKEHDLIFLHCEAAFDELLDIAYVWKHNG 888 Query: 147 QTLL--FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 + L DG R+ +VD L + + DAG Y+C+ ++A Sbjct: 889 EVLKNNHDGTGRI-IVDWNRLTVHNTSMRDAGDYECVVKSA 928 Score = 43.2 bits (97), Expect = 0.044 Identities = 33/132 (25%), Positives = 59/132 (44%), Gaps = 7/132 (5%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753 I L+ T Y ++ + EG S +T P PP ++ ++ +N +TV + W Sbjct: 1219 IVGLQPDTYYFVKVMAYNAAGEGPESERFEERTYRKAPQKPPSSVHVYGINPSTVRVVWR 1278 Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTV---HQATSLIMTNLTSGVSYSVQI 810 + GY V + W ++++M+ N T+ Q + NLT G SY++++ Sbjct: 1279 YVSPSQDEEPVEGYKVRI-W---ESDQNMITANNTIVPIGQKLESYINNLTPGKSYNMRV 1334 Query: 811 AAETIIGLGPFS 822 A + G G S Sbjct: 1335 LAYSNGGDGRMS 1346 >UniRef50_UPI0000519A30 Cluster: PREDICTED: similar to Peroxidasin CG12002-PA, isoform A; n=2; Apocrita|Rep: PREDICTED: similar to Peroxidasin CG12002-PA, isoform A - Apis mellifera Length = 1293 Score = 124 bits (300), Expect = 1e-26 Identities = 89/292 (30%), Positives = 131/292 (44%), Gaps = 15/292 (5%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I+ P DV V + C G P P I+W + V +D + ++ G + Sbjct: 237 PRIMNGPQDVEVRLGGTISFTCEVIGDPIPEIKWMRDSNEVSADGNHYVIQEDGTLIISD 296 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECL 130 D G Y C A + G +SR A + V F PES+ G V C Sbjct: 297 V---TEQDTGEYECVAKSEMGLTKSRKARAVITVSPSLRFTELPESQTVQIGVDVSFTC- 352 Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTR 189 G P PN+ W +NGQ L G R+ + + G+L+ I ++TD RY C ARN+ G Sbjct: 353 KVDGRPTPNIQWWRNGQLLNVGG--RVAIENEGSLLKIFAVKETDTARYVCQARNSNGYA 410 Query: 190 ESAIATLKI----HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 E++ A L + + P + P D+ A+ G+ + CRV G P P + W++ G M Sbjct: 411 ETS-ADLNVVDESYSPPRMTYEPHDMEAEPGTIIEVPCRVEGVPKPVIQWKKD--GTAME 467 Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297 R ++ GSL L NV D G Y C A N G +A + V P + ++ Sbjct: 468 GERFRISRGGSLYLYNVTAGDTGRYECSAVNQYGRATAQALVRVRQPEATDV 519 Score = 123 bits (297), Expect = 3e-26 Identities = 81/300 (27%), Positives = 139/300 (46%), Gaps = 14/300 (4%) Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLD 260 +P ++ GP+DV + G +++F C V GDP+P++ W R + + + +DG+L + Sbjct: 236 EPRIMNGPQDVEVRLGGTISFTCEVIGDPIPEIKWMRDSNEVSADGNHYVIQEDGTLIIS 295 Query: 261 NVILADEGEYSCEAENSVGAV-SASGYLTVYDPPSINLS--PNSVNVESGNVARFTCTAT 317 +V D GEY C A++ +G S + PS+ + P S V+ G FTC Sbjct: 296 DVTEQDTGEYECVAKSEMGLTKSRKARAVITVSPSLRFTELPESQTVQIGVDVSFTCKVD 355 Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377 GRP P + W G ++ G A+ + ++L I + D+ VC A N Sbjct: 356 GRPTPNIQWWRNGQ--LLNVG------GRVAIENEGSLLKIFAVKETDTAR-YVCQARNS 406 Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437 G + L V D+ PP +T P + ++ PC P+P+I W +G A Sbjct: 407 NGYAETSADLNVV-DESYSPPRMTYEPHDMEAEPGTIIEVPCRVEGVPKPVIQWKKDGTA 465 Query: 438 LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRA 497 + + R ++ G+L L ++ D+G Y C A +++G+ + V P ++ RA Sbjct: 466 M-EGERFRISRGGSLYLYNVTAGDTGRYECSAVNQYGRATAQALVRVRQPEATDVLVIRA 524 Score = 118 bits (283), Expect = 1e-24 Identities = 76/247 (30%), Positives = 116/247 (46%), Gaps = 15/247 (6%) Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT 173 P+ + G T+ C G P P + W ++ + DG+ + + + G L+I D + Sbjct: 243 PQDVEVRLGGTISFTC-EVIGDPIPEIKWMRDSNEVSADGNHYV-IQEDGTLIISDVTEQ 300 Query: 174 DAGRYQCIARNAAGTRESAIATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLP 231 D G Y+C+A++ G +S A I + P L PE Q G V+F C+V G P P Sbjct: 301 DTGEYECVAKSEMGLTKSRKARAVITVSPSLRFTELPESQTVQIGVDVSFTCKVDGRPTP 360 Query: 232 DVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTV- 289 ++ W R+ N+ GRV + ++GS L++ V D Y C+A NS G S L V Sbjct: 361 NIQWWRNGQLLNVG-GRVAIENEGSLLKIFAVKETDTARYVCQARNSNGYAETSADLNVV 419 Query: 290 ---YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW-----SVEGNRTIIFPGMSR 341 Y PP + P+ + E G + C G P+P + W ++EG R I G S Sbjct: 420 DESYSPPRMTYEPHDMEAEPGTIIEVPCRVEGVPKPVIQWKKDGTAMEGERFRISRGGSL 479 Query: 342 DKYHATA 348 Y+ TA Sbjct: 480 YLYNVTA 486 >UniRef50_UPI0000D560FB Cluster: PREDICTED: similar to CG1084-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG1084-PA - Tribolium castaneum Length = 1192 Score = 124 bits (298), Expect = 2e-26 Identities = 118/498 (23%), Positives = 190/498 (38%), Gaps = 45/498 (9%) Query: 12 PYIIEQPLDVTVAR-----HQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP---- 62 PY I+QP+D T + +L+C AGG P+P W++ + R I P Sbjct: 251 PYFIKQPVDATFDSSKKMLYNDISLSCLAGGFPTPTYEWFREDYEIDKLVARRIDPLSDP 310 Query: 63 ----AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESK 117 +GG+ + + D Y C+A+N +GT S + L+ ++E + PES Sbjct: 311 RYTISGGMLIIHEPEEK--RDHATYHCKASNKFGTIISESVQLNFGFIKEFVLKRSPESG 368 Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR 177 G + C PP P W ++ + D R+ + G L D Sbjct: 369 DKNWGKAIY--CDPPNHFPSVRYSWSRDYFPNFVEEDRRVFVSYDGALYFSALETIDKAN 426 Query: 178 YQCIARN--AAGTRESAIATLKI--HIKPYLITGPEDVVAQ------TGSSVTFQCRVGG 227 Y C ++ + R L + H + P + G V +C G Sbjct: 427 YSCSVQSEFSDSGRNGPFFPLMVNPHSHYQQLKFPNNFPKAFPDAPIAGKEVRLECMAFG 486 Query: 228 DPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYL 287 P+P W R G +P V + L + +V + D+GEY C A N + S L Sbjct: 487 YPVPSYNWTRR--GAPLPRSAVLSSFNRVLTIPHVQVEDQGEYVCRAYNDRASTENSLIL 544 Query: 288 TVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347 + P+ + + +S + +TC A G P+ W G + + RD+ Sbjct: 545 NIQAEPNFTIPLADRHADSKSELVWTCEAFGIPDVNYTWWKNGRQ------LERDRIR-- 596 Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407 + D V LTI D+ C A N + + +L V + P + + Sbjct: 597 -IQDNV--LTIRYLDQERDPGMYQCRATNSLKTKYSSAQLRVLAFR---PTFKKHPLEAE 650 Query: 408 TLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYT 466 T + +V C P P W +G L R + +G LV+ + + D G YT Sbjct: 651 TYAAEGGSVTIKCNPEAAPRPEFVWKKDGNVLGSGGHRRILENGNLVISSVSRDDEGQYT 710 Query: 467 CVASSRHGKYVWSGALLV 484 C AS++ G G L+V Sbjct: 711 CRASNQFGVDESKGRLIV 728 Score = 100 bits (239), Expect = 3e-19 Identities = 80/270 (29%), Positives = 117/270 (43%), Gaps = 19/270 (7%) Query: 33 CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG 92 C A G P W+K G + D R + +R D G+Y C ATNS Sbjct: 571 CEAFGIPDVNYTWWKNGRQLERDRIRI---QDNVLTIRYLDQE--RDPGMYQCRATNSLK 625 Query: 93 TARSRNATLHVAVLREEFRLEPESKQS--AQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150 T S +A L V R F+ P ++ A+G +V ++C P +P P WKK+G L Sbjct: 626 TKYS-SAQLRVLAFRPTFKKHPLEAETYAAEGGSVTIKC-NPEAAPRPEFVWKKDGNVLG 683 Query: 151 FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG-PE 209 G R +++ GNLVI + D G+Y C A N G ES L + P LI Sbjct: 684 SGGHRR--ILENGNLVISSVSRDDEGQYTCRASNQFGVDESK-GRLIVLRGPRLIESLTP 740 Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL------DDGSLRLDNVI 263 +V G +C + + D+ + S G + +K + D G L + N Sbjct: 741 KIVTTVGRYFDLRCLAETEEMLDIAYVWSHNGIKIRDIDIKNMNYRLRIDGGFLSVTNAT 800 Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPP 293 D GEY C +++VG +S+ + V PP Sbjct: 801 FTDAGEYECTIKSTVGKISSRSVVVVEGPP 830 Score = 91.9 bits (218), Expect = 1e-16 Identities = 76/276 (27%), Positives = 120/276 (43%), Gaps = 16/276 (5%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 L C A G P P+ W + G + RS + + L H +V D G Y C A N Sbjct: 480 LECMAFGYPVPSYNWTRRG----APLPRSAVLSSFNRVLTIPHVQVE-DQGEYVCRAYND 534 Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150 A + N+ + F + + + +V C G P+ N W KNG+ L Sbjct: 535 --RASTENSLILNIQAEPNFTIPLADRHADSKSELVWTC-EAFGIPDVNYTWWKNGRQLE 591 Query: 151 FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP-- 208 D R+ + D + ++ D G YQC A N+ T+ S+ + +P P Sbjct: 592 RD---RIRIQDNVLTIRYLDQERDPGMYQCRATNSLKTKYSSAQLRVLAFRPTFKKHPLE 648 Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268 + A G SVT +C P P+ +W++ G G ++L++G+L + +V DEG Sbjct: 649 AETYAAEGGSVTIKCNPEAAPRPEFVWKKD-GNVLGSGGHRRILENGNLVISSVSRDDEG 707 Query: 269 EYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSV 302 +Y+C A N G + G L V P + +L+P V Sbjct: 708 QYTCRASNQFGVDESKGRLIVLRGPRLIESLTPKIV 743 Score = 60.5 bits (140), Expect = 3e-07 Identities = 50/182 (27%), Positives = 72/182 (39%), Gaps = 11/182 (6%) Query: 12 PYIIEQPLDVTV--ARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 P + PL+ A T+ C +P P W K G ++ S HR IL G L Sbjct: 640 PTFKKHPLEAETYAAEGGSVTIKCNPEAAPRPEFVWKKDGNVLGSGGHRRILENGNLVIS 699 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 + D G Y C A+N +G S+ + + R L P+ + G L C Sbjct: 700 SVS----RDDEGQYTCRASNQFGVDESKGRLIVLRGPRLIESLTPKIVTTV-GRYFDLRC 754 Query: 130 LPPRGSPEPNVY-WKKNGQTLLFDGDSRMHL---VDGGNLVIQDARQTDAGRYQCIARNA 185 L Y W NG + M+ +DGG L + +A TDAG Y+C ++ Sbjct: 755 LAETEEMLDIAYVWSHNGIKIRDIDIKNMNYRLRIDGGFLSVTNATFTDAGEYECTIKST 814 Query: 186 AG 187 G Sbjct: 815 VG 816 >UniRef50_UPI0000D55944 Cluster: PREDICTED: similar to CG8967-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG8967-PA - Tribolium castaneum Length = 1094 Score = 123 bits (297), Expect = 3e-26 Identities = 116/416 (27%), Positives = 172/416 (41%), Gaps = 33/416 (7%) Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREE---FRLEPESKQSAQGDTVVLECLPPRG 134 SD GVY C A N+ G AR +AV EE ++ P + QG T +C + Sbjct: 183 SDNGVYRCLANNTAG-ARYSTTNFALAVAGEETALIQVVPRDQLVPQGGTAYFDCQYQQA 241 Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR--ESA 192 Y+KK+ + L + + + G L I D + D G Y C+ + T +S Sbjct: 242 EVT-EWYFKKDTRPL--ENGKKFVIHSNGTLQINDVQGKDQGFYSCVGIRSESTEIPQSY 298 Query: 193 IATLKI---------HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 IA LK+ +P L VVA G C P W + GG Sbjct: 299 IAELKLAYLSEFTVNSFEPPLSENSNQVVAPEGGLFQLTCLEPDSLPPAKKWWLNTGGHT 358 Query: 244 MP-LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302 + G V+V DDG L ++ V + G Y+C AEN G L V + P + P SV Sbjct: 359 VSDSGEVRV-DDGRLIIEKVRMDHAGNYTCVAENMAGKTEKIIELVVLNKPVVTAQPLSV 417 Query: 303 NVESGNVARFTCTATGRPEPTMF-WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361 V+ + TC + T+ W +G G + +F L I +T Sbjct: 418 TVDENEPSMLTCDYEPKNHFTIVKWRKDGKSLRHDFGENSLDRQRIKIFKHNASLVIRET 477 Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR---PPPIITNGPSNQTLPIKSMAVFP 418 + +D R VC + + T++ + PPP+ N+ L + S+A Sbjct: 478 ESHD-RGEYVCEVLAKGFEPVLSEPATISVIEKLKFVPPPV------NKKLELGSVAKVH 530 Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 C A TP PII W GE+ ++ R ++ +GTLV + D G YTCVA++ G Sbjct: 531 CKAQGTPPPIITWEKLGESF--DNSRIISMNGTLVFNGVLNEDKGKYTCVATNSQG 584 Score = 103 bits (247), Expect = 3e-20 Identities = 79/276 (28%), Positives = 125/276 (45%), Gaps = 15/276 (5%) Query: 12 PYIIEQPLDVTVARHQPATLNCR-AGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 P + QPL VTV ++P+ L C + ++W K G + D + L + + Sbjct: 408 PVVTAQPLSVTVDENEPSMLTCDYEPKNHFTIVKWRKDGKSLRHDFGENSLDRQRIKIFK 467 Query: 71 ATHGRV-----HSDAGVYWCEA-TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124 V D G Y CE + S AT+ V + + +F P +K+ G Sbjct: 468 HNASLVIRETESHDRGEYVCEVLAKGFEPVLSEPATISV-IEKLKFVPPPVNKKLELGSV 526 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 + C +G+P P + W+K G++ FD +SR+ ++G LV D G+Y C+A N Sbjct: 527 AKVHC-KAQGTPPPIITWEKLGES--FD-NSRIISMNG-TLVFNGVLNEDKGKYTCVATN 581 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 + G I + + + P P++ T G SVT C V GDP P + W ++ + Sbjct: 582 SQGVINVTI-NIDVVVAPKFSVEPKNPTEVTEGQSVTIDCVVEGDPKPTIHWDKNLKMND 640 Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279 R VL++G+L + V DE +Y C A NS G Sbjct: 641 FDHSRFTVLENGTLFISEVHREDENKYGCTAGNSAG 676 Score = 102 bits (245), Expect = 5e-20 Identities = 124/493 (25%), Positives = 188/493 (38%), Gaps = 52/493 (10%) Query: 8 SGEAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWY-KGGVLVVSDTHRSILPAGG 65 +GE +I+ P D V + A +C+ + WY K + + + ++ + G Sbjct: 210 AGEETALIQVVPRDQLVPQGGTAYFDCQY--QQAEVTEWYFKKDTRPLENGKKFVIHSNG 267 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTA--RSRNATLHVAVLRE------EFRLEPESK 117 + G+ D G Y C S T +S A L +A L E E L S Sbjct: 268 TLQINDVQGK---DQGFYSCVGIRSESTEIPQSYIAELKLAYLSEFTVNSFEPPLSENSN 324 Query: 118 Q--SAQGDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTD 174 Q + +G L CL P P +W G T+ G+ R VD G L+I+ R Sbjct: 325 QVVAPEGGLFQLTCLEPDSLPPAKKWWLNTGGHTVSDSGEVR---VDDGRLIIEKVRMDH 381 Query: 175 AGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGG-DPLPDV 233 AG Y C+A N AG E I + ++ KP + P V C + V Sbjct: 382 AGNYTCVAENMAGKTEKIIELVVLN-KPVVTAQPLSVTVDENEPSMLTCDYEPKNHFTIV 440 Query: 234 LWRRSA-------GGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCE--AENSVGAVSA 283 WR+ G ++ R+K+ + SL + D GEY CE A+ +S Sbjct: 441 KWRKDGKSLRHDFGENSLDRQRIKIFKHNASLVIRETESHDRGEYVCEVLAKGFEPVLSE 500 Query: 284 SGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDK 343 ++V + P + +E G+VA+ C A G P P + W G F Sbjct: 501 PATISVIEKLKFVPPPVNKKLELGSVAKVHCKAQGTPPPIITWEKLGES---FDNSRIIS 557 Query: 344 YHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG 403 + T VF+GV N+ + C A N G V + V P + Sbjct: 558 MNGTLVFNGVL---------NEDKGKYTCVATNSQGVINVTINIDVVV-----APKFSVE 603 Query: 404 PSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKDLDKSD 461 P N T + +V C P+P I W + +H R V +GTL + ++ + D Sbjct: 604 PKNPTEVTEGQSVTIDCVVEGDPKPTIHWDKNLKMNDFDHSRFTVLENGTLFISEVHRED 663 Query: 462 SGTYTCVASSRHG 474 Y C A + G Sbjct: 664 ENKYGCTAGNSAG 676 Score = 87.0 bits (206), Expect = 3e-15 Identities = 101/409 (24%), Positives = 167/409 (40%), Gaps = 33/409 (8%) Query: 1 MSDDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRS 59 +S+ V S E P + E V L C S PA +W+ G VSD+ Sbjct: 307 LSEFTVNSFEPP-LSENSNQVVAPEGGLFQLTCLEPDSLPPAKKWWLNTGGHTVSDSGEV 365 Query: 60 ILPAGGLFFLRATHGRVHSD-AGVYWCEATNSYGTARSRNATLHVAVLREEF-RLEPESK 117 + G L +V D AG Y C A N G + + VL + +P S Sbjct: 366 RVDDGRLII-----EKVRMDHAGNYTCVAENMAGKTEK---IIELVVLNKPVVTAQPLSV 417 Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFD-GDSRMH------LVDGGNLVIQDA 170 + + +L C + V W+K+G++L D G++ + +LVI++ Sbjct: 418 TVDENEPSMLTCDYEPKNHFTIVKWRKDGKSLRHDFGENSLDRQRIKIFKHNASLVIRET 477 Query: 171 RQTDAGRYQC-IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP 229 D G Y C + S AT+ + K + P + + GS C+ G P Sbjct: 478 ESHDRGEYVCEVLAKGFEPVLSEPATISVIEKLKFVPPPVNKKLELGSVAKVHCKAQGTP 537 Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 P + W + G + R+ + +G+L + V+ D+G+Y+C A NS G ++ + + V Sbjct: 538 PPIITWEKL--GESFDNSRI-ISMNGTLVFNGVLNEDKGKYTCVATNSQGVINVTINIDV 594 Query: 290 YDPPSINLSP-NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348 P ++ P N V G C G P+PT+ W ++ + ++ T Sbjct: 595 VVAPKFSVEPKNPTEVTEGQSVTIDCVVEGDPKPTIHW----DKNLKMNDFDHSRF--TV 648 Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397 + +G L I++ + D N C+A N AG + +L V S D P Sbjct: 649 LENG--TLFISEVHRED-ENKYGCTAGNSAGLNRQEVQLIVHSRDGYHP 694 Score = 78.6 bits (185), Expect = 1e-12 Identities = 119/496 (23%), Positives = 195/496 (39%), Gaps = 59/496 (11%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 V E PY E P +V V + + TL C+ W G + + T R Sbjct: 17 VIGKEDPYFSESPRNVDVVQGKSVTLPCKVTPGIGMTYYWELNGSKIANTTRRH-QQGSN 75 Query: 66 LFFLRATHGRVHSDAGVYWCEATNS----YGTARSRNATLHVAVLRE-EFRL-EPESKQ- 118 L R R D+G + C A +S G+ RS A+L++ + E +L EPES Sbjct: 76 LHITRVDRER---DSGQFTCIAEDSTSSLAGSIRSSEASLNIQWIDEVSVQLQEPESASF 132 Query: 119 SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY 178 ++G V L C S + + W +N LL S + L I++ +D G Y Sbjct: 133 ISRGSDVTLRC-HTDASGDVHYEWFRNSDRLL---KSDKIEIKKKRLHIKNVGPSDNGVY 188 Query: 179 QCIARNAAGTRESA--IATLKIHIKPYLI-TGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235 +C+A N AG R S A + LI P D + G + F C+ + + W Sbjct: 189 RCLANNTAGARYSTTNFALAVAGEETALIQVVPRDQLVPQGGTAYFDCQYQQAEVTE--W 246 Query: 236 RRSAGGGNMPLGRVKVL-DDGSLRLDNVILADEGEYSC--------EAENSVGAVSASGY 286 + G+ V+ +G+L++++V D+G YSC E S A Y Sbjct: 247 YFKKDTRPLENGKKFVIHSNGTLQINDVQGKDQGFYSCVGIRSESTEIPQSYIAELKLAY 306 Query: 287 LTVYD----PPSINLSPNSVNVESGNVARFTC-TATGRPEPTMFWSVEGNRTIIFPGMSR 341 L+ + P ++ + N V G + + TC P +W G T+ G R Sbjct: 307 LSEFTVNSFEPPLSENSNQVVAPEGGLFQLTCLEPDSLPPAKKWWLNTGGHTVSDSGEVR 366 Query: 342 DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401 V DG ++ + + D C A N AG + +L V + P++T Sbjct: 367 -------VDDGRLII---EKVRMDHAGNYTCVAENMAGKTEKIIELVVLN-----KPVVT 411 Query: 402 NGPSNQTLPIKSMAVFPCTAICTPE-PIIAWYFEGEALIQNHRRN---------VTNDGT 451 P + T+ ++ C I+ W +G++L + N ++ + Sbjct: 412 AQPLSVTVDENEPSMLTCDYEPKNHFTIVKWRKDGKSLRHDFGENSLDRQRIKIFKHNAS 471 Query: 452 LVLKDLDKSDSGTYTC 467 LV+++ + D G Y C Sbjct: 472 LVIRETESHDRGEYVC 487 >UniRef50_A7RGL7 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 553 Score = 123 bits (297), Expect = 3e-26 Identities = 116/387 (29%), Positives = 163/387 (42%), Gaps = 28/387 (7%) Query: 105 VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN 164 +LR E K A+ D E L EP+V W +N ++ DG SR DG Sbjct: 179 ILRSEEEDAGSYKCLARNDVGSAERLFEVQVEEPSVTWYRNKNEIVPDGRSRTTF-DGET 237 Query: 165 --LVIQDARQTDAGRYQCIARNAAGTRE-SAIATLKIHIKPYLITGPEDVVAQTGSSVTF 221 L++QD + DAG+Y+CIA N G +A T+ P ++ + G +V++ Sbjct: 238 YKLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKREAPVFVSKLRPLFVTEGDNVSW 297 Query: 222 QCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDG---SLRLDNVILADEGEYSCEAE 275 C+V G P P V W R N PL R K+ DG SL L D+G Y+C Sbjct: 298 MCKVAGMPRPTVEWYRD----NQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVIT 353 Query: 276 NSVGAVSASGYLTV---YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332 NS G+ +S L V + P + N V G ARF +G P P + W + Sbjct: 354 NSAGSAFSSAELQVDKKANKPKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSIK 413 Query: 333 TIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD 392 + ++H + D + LTI DT D+ T C A N G RG L V Sbjct: 414 V-----RNESRFHLSEDGDRYS-LTITDTKLVDT-GTYKCVATNEGGKITSRGDLDVRER 466 Query: 393 DDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG- 450 P + + +S A+ F P P I WY +GE + R + + G Sbjct: 467 QFAPEFYGDDELKEPVVVQESDAINFKVRVRGKPVPTIVWYKDGEMVRDVRRFEIRSRGD 526 Query: 451 --TLVLKDLDKSDSGTYTCVASSRHGK 475 T D+GTYTC AS++ GK Sbjct: 527 IYTFATYSASAEDAGTYTCEASNKLGK 553 Score = 115 bits (277), Expect = 7e-24 Identities = 126/491 (25%), Positives = 202/491 (41%), Gaps = 59/491 (12%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68 G+ P + + + + L+C G P P ++W++ VL+ G + Sbjct: 13 GDTPTFMSKLEPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSA 72 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVL 127 L + D GVY C TN++G+ S+ + T+ LR E P ++ + + + Sbjct: 73 LTVKEAELDDD-GVYKCVVTNNFGSVSSKADVTVLKKHLRPERDYAPIFEEKQFLEPLEI 131 Query: 128 ECLPP-------RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG---NLVIQDARQTDAGR 177 + P RG P+P V W KNG+ L DG + + GG L I + + DAG Sbjct: 132 QVRQPVEVSYHVRGRPKPTVTWWKNGKELR-DG-KHVEIRSGGTYHTLYILRSEEEDAGS 189 Query: 178 YQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 Y+C+ARN G SA ++ ++ SVT+ R + +PD R Sbjct: 190 YKCLARNDVG---SAERLFEVQVEE--------------PSVTWY-RNKNEIVPDGRSRT 231 Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV--YDPPSI 295 + G L +L D + + D G+Y C A N +G + +TV + P Sbjct: 232 TFDGETYKL----ILQD-------IKIKDAGQYECIASNPIGKAFCTAEMTVNKREAPVF 280 Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG-VT 354 + V G+ + C G P PT+ W N+ + R FDG V Sbjct: 281 VSKLRPLFVTEGDNVSWMCKVAGMPRPTVEW-YRDNQPL------RADTRWKMDFDGRVC 333 Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414 L +++ D D + C N AGS+F +L V ++ P +I QT+ + Sbjct: 334 SLFLSEADCKD-KGVYNCVITNSAGSAFSSAELQVDKKANK-PKVIEKMNDVQTVE-GTE 390 Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASS 471 A F P P + WY + R +++ DG +L + D D+GTY CVA++ Sbjct: 391 ARFDVRFSGLPRPEVTWYRNSIKVRNESRFHLSEDGDRYSLTITDTKLVDTGTYKCVATN 450 Query: 472 RHGKYVWSGAL 482 GK G L Sbjct: 451 EGGKITSRGDL 461 Score = 91.5 bits (217), Expect = 1e-16 Identities = 77/287 (26%), Positives = 123/287 (42%), Gaps = 19/287 (6%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 V EAP + + + V + C+ G P P + WY+ + +DT + G Sbjct: 272 VNKREAPVFVSKLRPLFVTEGDNVSWMCKVAGMPRPTVEWYRDNQPLRADTRWKMDFDGR 331 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL--EPESKQSAQGD 123 + L + D GVY C TNS G+A S +A L V + ++ + Q+ +G Sbjct: 332 VCSLFLSEADC-KDKGVYNCVITNSAGSAFS-SAELQVDKKANKPKVIEKMNDVQTVEGT 389 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG---NLVIQDARQTDAGRYQC 180 + + G P P V W +N ++ +SR HL + G +L I D + D G Y+C Sbjct: 390 EARFD-VRFSGLPRPEVTWYRN--SIKVRNESRFHLSEDGDRYSLTITDTKLVDTGTYKC 446 Query: 181 IARNAAG--TRESAIATLKIHIKPYLITG---PEDVVAQTGSSVTFQCRVGGDPLPDVLW 235 +A N G T + + P E VV Q ++ F+ RV G P+P ++W Sbjct: 447 VATNEGGKITSRGDLDVRERQFAPEFYGDDELKEPVVVQESDAINFKVRVRGKPVPTIVW 506 Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILA---DEGEYSCEAENSVG 279 + G + R ++ G + A D G Y+CEA N +G Sbjct: 507 YKD-GEMVRDVRRFEIRSRGDIYTFATYSASAEDAGTYTCEASNKLG 552 Score = 90.2 bits (214), Expect = 3e-16 Identities = 89/311 (28%), Positives = 129/311 (41%), Gaps = 33/311 (10%) Query: 41 PAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG-------- 92 P++ WY+ +V D G + L ++ DAG Y C A+N G Sbjct: 212 PSVTWYRNKNEIVPDGRSRTTFDGETYKLILQDIKI-KDAGQYECIASNPIGKAFCTAEM 270 Query: 93 TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFD 152 T R A + V+ LR F E GD V C G P P V W ++ Q L D Sbjct: 271 TVNKREAPVFVSKLRPLFVTE--------GDNVSWMC-KVAGMPRPTVEWYRDNQPLRAD 321 Query: 153 GDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGTRESA--IATLKIHIKPYLITGP 208 +M DG +L + +A D G Y C+ N+AG+ S+ + K KP +I Sbjct: 322 TRWKMDF-DGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKANKPKVIEKM 380 Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---SLRLDNVILA 265 DV G+ F R G P P+V W R++ R + +DG SL + + L Sbjct: 381 NDVQTVEGTEARFDVRFSGLPRPEVTWYRNSIKVRNE-SRFHLSEDGDRYSLTITDTKLV 439 Query: 266 DEGEYSCEAENSVGAVSASGYLTVYD---PPSI---NLSPNSVNVESGNVARFTCTATGR 319 D G Y C A N G +++ G L V + P + V V+ + F G+ Sbjct: 440 DTGTYKCVATNEGGKITSRGDLDVRERQFAPEFYGDDELKEPVVVQESDAINFKVRVRGK 499 Query: 320 PEPTMFWSVEG 330 P PT+ W +G Sbjct: 500 PVPTIVWYKDG 510 Score = 53.6 bits (123), Expect = 3e-05 Identities = 49/188 (26%), Positives = 71/188 (37%), Gaps = 13/188 (6%) Query: 321 EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGS 380 EP++ W N I+ G SR FDG T I K C A N G Sbjct: 211 EPSVTWYRNKNE-IVPDGRSR------TTFDGETYKLILQDIKIKDAGQYECIASNPIGK 263 Query: 381 SFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ 440 +F ++TV R P+ + + + C P P + WY + + L Sbjct: 264 AFCTAEMTVNK---REAPVFVSKLRPLFVTEGDNVSWMCKVAGMPRPTVEWYRDNQPLRA 320 Query: 441 NHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRA 497 + R + DG +L L + D D G Y CV ++ G S L VD N + Sbjct: 321 DTRWKMDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKANKPKVIEKM 380 Query: 498 ADVSSLPG 505 DV ++ G Sbjct: 381 NDVQTVEG 388 Score = 43.2 bits (97), Expect = 0.044 Identities = 40/154 (25%), Positives = 60/154 (38%), Gaps = 15/154 (9%) Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250 S +A K P ++ E + G C V G P P+V W R P R K Sbjct: 5 SLLALQKKGDTPTFMSKLEPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIK-PSRRFK 63 Query: 251 VLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP---PSINLSP----- 299 DG+ L + L D+G Y C N+ G+VS+ +TV P + +P Sbjct: 64 ASYDGNVSALTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKKHLRPERDYAPIFEEK 123 Query: 300 ---NSVNVESGNVARFTCTATGRPEPTMFWSVEG 330 + ++ + GRP+PT+ W G Sbjct: 124 QFLEPLEIQVRQPVEVSYHVRGRPKPTVTWWKNG 157 >UniRef50_UPI00006A0696 Cluster: DDM36; n=4; Tetrapoda|Rep: DDM36 - Xenopus tropicalis Length = 932 Score = 123 bits (296), Expect = 3e-26 Identities = 131/474 (27%), Positives = 182/474 (38%), Gaps = 52/474 (10%) Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198 NV WKK+G L D R+ L +G L+ Q R GRY C A+++ G T+++ Sbjct: 32 NVTWKKDGVQLNSDEALRV-LRNGSLLISQMERDNIEGRYSCAAQDSVGIVTGRSHTVRL 90 Query: 199 HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGSL 257 P PE S F+C G P P+V W++ +P R L G L Sbjct: 91 ASLPSFHQQPESQTVMLNSMARFECGFSGFPPPEVTWQKDQAP--VPAESRFLTLPTGVL 148 Query: 258 RLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPS---------INLSPNSVNVESG 307 ++ V DEG Y C A N + + S+ +L+V S I +P ++ VE G Sbjct: 149 QISGVQEKDEGFYRCMATNILNSSYSSEAHLSVEQDASVYTLAEELTITRAPQNITVEEG 208 Query: 308 NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367 + A C A G P + W E + I S D G T L + + Sbjct: 209 HSAIMECMAKGNIVPLVSWIREDGKPI-----SSD-----VKLLGETNLLVPQAQPPHA- 257 Query: 368 NTIVCSAVNYAGSSFVRGKLTVTSD-DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426 VC A R +T T+ PIIT P T A F C A PE Sbjct: 258 GVYVCRA----NKPHTRHFITATAQLHILVHPIITQPPETITRARAGTARFVCRAEGEPE 313 Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486 P I W G+ L+ N R + G+LV+ L D G Y C+A + G + L V Sbjct: 314 PTIHWLKNGQPLLSNGRVRIQPRGSLVITQLALEDVGYYQCLAENSVGSACATAKLYVTV 373 Query: 487 PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRE 546 LPGPP V+ SVT+ W Q ++G+ + Sbjct: 374 Q-------------DGLPGPPQAVKAVTVSSRSVTVGWEQPES-NWERVIGFSLHY---- 415 Query: 547 TLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600 T +G + + A T V+ L PG Y F V + G S SP Sbjct: 416 TKTGGSDNMEYQ----FAVNNDTTELYVRDLEPGTKYTFYVVAYSQQGASSASP 465 Score = 121 bits (292), Expect = 1e-25 Identities = 112/399 (28%), Positives = 177/399 (44%), Gaps = 30/399 (7%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P +QP TV + A C G P P + W K V +++ LP G L Sbjct: 94 PSFHQQPESQTVMLNSMARFECGFSGFPPPEVTWQKDQAPVPAESRFLTLPTGVL----Q 149 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVA------VLREEFRLE--PESKQSAQGD 123 G D G Y C ATN ++ S A L V L EE + P++ +G Sbjct: 150 ISGVQEKDEGFYRCMATNILNSSYSSEAHLSVEQDASVYTLAEELTITRAPQNITVEEGH 209 Query: 124 TVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182 + ++EC+ +G+ P V W +++G+ + D + L+ NL++ A+ AG Y C A Sbjct: 210 SAIMECMA-KGNIVPLVSWIREDGKPISSD----VKLLGETNLLVPQAQPPHAGVYVCRA 264 Query: 183 RNAAGTRESAIATLKIHI--KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 N TR AT ++HI P + PE + + F CR G+P P + W ++ G Sbjct: 265 -NKPHTRHFITATAQLHILVHPIITQPPETITRARAGTARFVCRAEGEPEPTIHWLKN-G 322 Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASG--YLTVYDP-PSINL 297 + GRV++ GSL + + L D G Y C AENSVG+ A+ Y+TV D P Sbjct: 323 QPLLSNGRVRIQPRGSLVITQLALEDVGYYQCLAENSVGSACATAKLYVTVQDGLPGPPQ 382 Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 + +V V S +V E + +S+ +T G S + + AV + T L Sbjct: 383 AVKAVTVSSRSVTVGWEQPESNWERVIGFSLHYTKT----GGSDNMEYQFAVNNDTTELY 438 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP 396 + D + ++ T A + G+S + + + D+ P Sbjct: 439 VRDLEPG-TKYTFYVVAYSQQGASSASPPVVIKTLDEVP 476 Score = 121 bits (291), Expect = 1e-25 Identities = 124/466 (26%), Positives = 191/466 (40%), Gaps = 40/466 (8%) Query: 27 QPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85 Q A L+C G P + W K GV + SD +L G L + + G Y C Sbjct: 16 QEAILHCEVGSREVPYNVTWKKDGVQLNSDEALRVLRNGSLLISQMERDNIE---GRYSC 72 Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145 A +S G R+ T+ +A L F +PES+ EC G P P V W+K+ Sbjct: 73 AAQDSVGIVTGRSHTVRLASL-PSFHQQPESQTVMLNSMARFEC-GFSGFPPPEVTWQKD 130 Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205 + +SR + G L I ++ D G Y+C+A N + S+ A L + + Sbjct: 131 QAPV--PAESRFLTLPTGVLQISGVQEKDEGFYRCMATNILNSSYSSEAHLSVEQDASVY 188 Query: 206 T---------GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR-VKVLDDG 255 T P+++ + G S +C G+ +P V W R G P+ VK+L + Sbjct: 189 TLAEELTITRAPQNITVEEGHSAIMECMAKGNIVPLVSWIREDG---KPISSDVKLLGET 245 Query: 256 SLRLDNVILADEGEYSCEAE--NSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313 +L + G Y C A ++ ++A+ L + P I P ++ ARF Sbjct: 246 NLLVPQAQPPHAGVYVCRANKPHTRHFITATAQLHILVHPIITQPPETITRARAGTARFV 305 Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373 C A G PEPT+ W G + ++ G R + + V +T L + D C Sbjct: 306 CRAEGEPEPTIHWLKNG-QPLLSNGRVRIQPRGSLV---ITQLALEDVGYYQ------CL 355 Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF 433 A N GS+ KL VT D P P T+ +S+ V E +I + Sbjct: 356 AENSVGSACATAKLYVTVQDGLPGP--PQAVKAVTVSSRSVTVGWEQPESNWERVIGFSL 413 Query: 434 E----GEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHG 474 G + ++ V ND T L ++DL+ T+ VA S+ G Sbjct: 414 HYTKTGGSDNMEYQFAVNNDTTELYVRDLEPGTKYTFYVVAYSQQG 459 Score = 82.6 bits (195), Expect = 6e-14 Identities = 75/236 (31%), Positives = 105/236 (44%), Gaps = 16/236 (6%) Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGG 65 T E I P ++TV A + C A G+ P + W + G + SD +L Sbjct: 189 TLAEELTITRAPQNITVEEGHSAIMECMAKGNIVPLVSWIREDGKPISSDV--KLLGETN 246 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDT 124 L +A AGVY C A N T AT + +L + PE+ A+ T Sbjct: 247 LLVPQAQ----PPHAGVYVCRA-NKPHTRHFITATAQLHILVHPIITQPPETITRARAGT 301 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 C G PEP ++W KNGQ LL +G R+ + G+LVI D G YQC+A N Sbjct: 302 ARFVC-RAEGEPEPTIHWLKNGQPLLSNG--RVRIQPRGSLVITQLALEDVGYYQCLAEN 358 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 + G+ A A L + ++ L P+ V A T SS + VG + P+ W R G Sbjct: 359 SVGS-ACATAKLYVTVQDGLPGPPQAVKAVTVSSRS--VTVGWEQ-PESNWERVIG 410 Score = 71.7 bits (168), Expect = 1e-10 Identities = 72/294 (24%), Positives = 119/294 (40%), Gaps = 20/294 (6%) Query: 207 GPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA 265 G V C VG +P +V W++ N ++VL +GSL + + Sbjct: 6 GQTHTVLLPDQEAILHCEVGSREVPYNVTWKKDGVQLNSDEA-LRVLRNGSLLISQMERD 64 Query: 266 D-EGEYSCEAENSVGAVSASGY-LTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPT 323 + EG YSC A++SVG V+ + + + PS + P S V ++ARF C +G P P Sbjct: 65 NIEGRYSCAAQDSVGIVTGRSHTVRLASLPSFHQQPESQTVMLNSMARFECGFSGFPPPE 124 Query: 324 MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383 + W + P SR T V + + + D+ R C A N SS+ Sbjct: 125 VTWQKDQAPV---PAESRFLTLPTGVLQ---ISGVQEKDEGFYR----CMATNILNSSYS 174 Query: 384 -RGKLTVTSDDD----RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438 L+V D IT P N T+ A+ C A P+++W E Sbjct: 175 SEAHLSVEQDASVYTLAEELTITRAPQNITVEEGHSAIMECMAKGNIVPLVSWIREDGKP 234 Query: 439 IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492 I + + + + L++ +G Y C A+ H ++ + + ++P I Sbjct: 235 ISSDVK-LLGETNLLVPQAQPPHAGVYVCRANKPHTRHFITATAQLHILVHPII 287 Score = 56.8 bits (131), Expect = 3e-06 Identities = 45/169 (26%), Positives = 72/169 (42%), Gaps = 6/169 (3%) Query: 685 HSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILN 744 H++ + L+ YTKYEF + +G S+ TL D P PP ++ + L+ Sbjct: 748 HTSASEEILVAGLKPYTKYEFQVRSNGVFVDGPYSDIVEKMTLPDRPSSPPADLVLQPLS 807 Query: 745 TTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGV 804 +V L W PP NGII Y +++ + M T S + L SG Sbjct: 808 QFSVQLHWRPP--VESNGIIAQY-LIMYTTNSSHPDEMWTFLTREGNIFSTEVQGLQSGA 864 Query: 805 SYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAG 853 Y ++ A+T+ G GP++ + + D+L MN I+ G Sbjct: 865 KYYFKMGAKTVSGWGPYTSALVVETLPPTPSADVLD---MNSVTGIIVG 910 Score = 53.6 bits (123), Expect = 3e-05 Identities = 39/186 (20%), Positives = 86/186 (46%), Gaps = 11/186 (5%) Query: 637 ELIEATPIDSKTIKLMWEI--LNFYYLEGLFIYFRPLDNI-TIEYEMKTILHSNDVSGFE 693 + ++A + S+++ + WE N+ + G +++ +EY+ +ND + Sbjct: 382 QAVKAVTVSSRSVTVGWEQPESNWERVIGFSLHYTKTGGSDNMEYQFAV---NNDTTELY 438 Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753 + L TKY F+++ + ++ S V +TLD+VP P ++ + + + +H+ W Sbjct: 439 VRDLEPGTKYTFYVVAYSQQGASSASPPVVIKTLDEVPAAAP-SLNLHNHSPSQLHVSWQ 497 Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAE 813 P +L NG I Y + + ++ ++ +++M + + Y V+I+A Sbjct: 498 PLLPELSNGQIIKYRIEYG---TQKDDDFSSVEVLGNETQAILMPVQLNSL-YKVRISAS 553 Query: 814 TIIGLG 819 T G G Sbjct: 554 TAAGYG 559 >UniRef50_Q4SI43 Cluster: Chromosome 5 SCAF14581, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 5 SCAF14581, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 782 Score = 123 bits (296), Expect = 3e-26 Identities = 133/512 (25%), Positives = 212/512 (41%), Gaps = 55/512 (10%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169 F ++PES + + +C G PEP + W+K+ + + D R L+ G L I Sbjct: 55 FHVQPESVHAEESGVARFQC-QIHGLPEPVISWEKDSRPV-DTSDERYTLLPTGVLQITG 112 Query: 170 ARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP 229 R D+GR+ C+A N+AG + SA A LK+ PY + SV+ Q V Sbjct: 113 LRLEDSGRFCCVAHNSAGVKHSAEAVLKVS-GPYSSALAHNKFIM--KSVSQQAFVLPQM 169 Query: 230 LPDVLWRRSAGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSAS--- 284 V++R+ + G + + ++ + L I SC + A+ S Sbjct: 170 YSSVIFRQYSQDFPGLLFIRLIREIQHIELMYSRGIQCKGSHPSCSFSSHAPALLLSFLP 229 Query: 285 ---GYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341 +VY P I + P ++ + A C ATG P P + WS R I G+ Sbjct: 230 PSGSQSSVYKEPMILVGPENLTLTVHQTAILECVATGYPRPIVSWSRLDGRPIGVEGIQ- 288 Query: 342 DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR---GKLTVTSDDDRPPP 398 G L I+D S VC+A N G+ R G+L V + P Sbjct: 289 --------VLGTGNLMISDVGVQHS-GVYVCAA-NKPGTRVRRTAQGRLVV-----QAPA 333 Query: 399 IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDL 457 P + + P+ + A+F C A PEP + W G+ L H + N+ TL + + Sbjct: 334 EFVQPPQSISRPVGTTAIFTCQARGEPEPQLTWLKNGQVLEPGGHVKLRNNNSTLTIYGI 393 Query: 458 DKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTD 517 + D Y C+A + G S L V AD LPG PT ++ Sbjct: 394 SQDDEAIYQCIAENSAGSTQASARLTV-----------LWAD--GLPGVPTGVQAEALSP 440 Query: 518 TSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSL 577 T++ +SW + ++ + I+GY + + R T + P +++ Q +V++ L Sbjct: 441 TTIQVSWKEPDQ-NTQEIIGYVLHI--RRT----SDPVEEEYEEAVSKVTLQ--HVIRDL 491 Query: 578 IPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 P +Y F V+ SHG S PS + T G+ Sbjct: 492 EPSTSYTFYVKAYTSHGASKPSESTTESTPGE 523 Score = 87.4 bits (207), Expect = 2e-15 Identities = 72/212 (33%), Positives = 93/212 (43%), Gaps = 9/212 (4%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I+ P ++T+ HQ A L C A G P P + W + + +L G L + Sbjct: 241 PMILVGPENLTLTVHQTAILECVATGYPRPIVSWSRLDGRPIGVEGIQVLGTGNLMI--S 298 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECL 130 G HS GVY C A N GT R A + V EF P+S G T + C Sbjct: 299 DVGVQHS--GVYVC-AANKPGTRVRRTAQGRLVVQAPAEFVQPPQSISRPVGTTAIFTC- 354 Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190 RG PEP + W KNGQ L G ++ + L I Q D YQCIA N+AG+ + Sbjct: 355 QARGEPEPQLTWLKNGQVLEPGGHVKLR-NNNSTLTIYGISQDDEAIYQCIAENSAGSTQ 413 Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQ 222 A A L + L P V A+ S T Q Sbjct: 414 -ASARLTVLWADGLPGVPTGVQAEALSPTTIQ 444 Score = 83.4 bits (197), Expect = 3e-14 Identities = 101/406 (24%), Positives = 159/406 (39%), Gaps = 48/406 (11%) Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG--RVKVLDDG 255 ++ +P ++ GPE++ + +C G P P V W R G P+G ++VL G Sbjct: 237 VYKEPMILVGPENLTLTVHQTAILECVATGYPRPIVSWSRLDG---RPIGVEGIQVLGTG 293 Query: 256 SLRLDNVILADEGEYSCEAENSVGAV--SASGYLTVYDPPSINLSPNSVNVESGNVARFT 313 +L + +V + G Y C A V +A G L V P P S++ G A FT Sbjct: 294 NLMISDVGVQHSGVYVCAANKPGTRVRRTAQGRLVVQAPAEFVQPPQSISRPVGTTAIFT 353 Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373 C A G PEP + W G ++ PG + + + LTI ++D C Sbjct: 354 CQARGEPEPQLTWLKNGQ--VLEPGGH------VKLRNNNSTLTIYGISQDDEA-IYQCI 404 Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF 433 A N AGS+ +LTV D P + G + L ++ V + II + Sbjct: 405 AENSAGSTQASARLTVLWADGLPG--VPTGVQAEALSPTTIQVSWKEPDQNTQEIIGYVL 462 Query: 434 EGEAL---IQNHRRNVTNDGTL--VLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPI 488 ++ + TL V++DL+ S S T+ A + HG S + +P Sbjct: 463 HIRRTSDPVEEEYEEAVSKVTLQHVIRDLEPSTSYTFYVKAYTSHGASKPSESTTESTP- 521 Query: 489 NPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETL 548 +P PPT T V + + W ++K+G GY R Sbjct: 522 ------------GEVPAPPTLH-TKVVNSSVIQAWWEPSSKMGQHQ--GY------RLYY 560 Query: 549 SGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHG 594 G P + G +++ Q Y + L P + Y + N HG Sbjct: 561 KGAQAPLFA-GPIILPPNASQ--YTITQLDPSLVYEIKLLAYNQHG 603 Score = 41.5 bits (93), Expect = 0.14 Identities = 31/89 (34%), Positives = 39/89 (43%), Gaps = 5/89 (5%) Query: 17 QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGR 75 QP V A C+ G P P I W K V SD ++LP G L+ T R Sbjct: 58 QPESVHAEESGVARFQCQIHGLPEPVISWEKDSRPVDTSDERYTLLPTG---VLQITGLR 114 Query: 76 VHSDAGVYWCEATNSYGTARSRNATLHVA 104 + D+G + C A NS G S A L V+ Sbjct: 115 L-EDSGRFCCVAHNSAGVKHSAEAVLKVS 142 Score = 38.3 bits (85), Expect = 1.3 Identities = 40/189 (21%), Positives = 74/189 (39%), Gaps = 14/189 (7%) Query: 639 IEATPIDSKTIKLMWEI--LNFYYLEGLFIYFRPL-DNITIEYEMKTILHSNDVSGFEIT 695 ++A + TI++ W+ N + G ++ R D + EYE S I Sbjct: 433 VQAEALSPTTIQVSWKEPDQNTQEIIGYVLHIRRTSDPVEEEYEEAV---SKVTLQHVIR 489 Query: 696 SLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPP 755 L T Y F++ + KPS S T +VP P ++ + ++N++ + W P Sbjct: 490 DLEPSTSYTFYVKAYTSHGASKPSESTTESTPGEVPAPPTLHTK--VVNSSVIQAWWEPS 547 Query: 756 ELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETI 815 Q+ GY + P + + Q T +T L + Y +++ A Sbjct: 548 SKMGQH---QGYRLYYKGAQAPLFAGPIILPPNASQYT---ITQLDPSLVYEIKLLAYNQ 601 Query: 816 IGLGPFSQK 824 G G +++ Sbjct: 602 HGDGNATER 610 Score = 37.5 bits (83), Expect = 2.2 Identities = 15/33 (45%), Positives = 19/33 (57%) Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326 S ++ P SV+ E VARF C G PEP + W Sbjct: 54 SFHVQPESVHAEESGVARFQCQIHGLPEPVISW 86 >UniRef50_UPI0000ECA0F8 Cluster: Neurofascin precursor.; n=3; Gallus gallus|Rep: Neurofascin precursor. - Gallus gallus Length = 1249 Score = 122 bits (295), Expect = 5e-26 Identities = 95/288 (32%), Positives = 144/288 (50%), Gaps = 15/288 (5%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGLFFL 69 APY +++P ++ +A + L CRA G+P P+I+W G + S + S AG Sbjct: 352 APYWLDEPQNLILAPGEDGRLVCRANGNPKPSIQWLVNGEPIEGSPPNPSREVAGDTIVF 411 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTVVL 127 R T ++ S A VY C A+N +G + NA + V + L P ++ + Q + L Sbjct: 412 RDT--QIGSSA-VYQCNASNEHGYLLA-NAFVSVLDVPPRI-LAPRNQLIKVIQYNRTRL 466 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDS-RMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186 +C P GSP P + W KNGQ + DG + + H + G+L + AR+ D G Y C+A N Sbjct: 467 DC-PFFGSPIPTLRWFKNGQGNMLDGGNYKAH--ENGSLEMSMARKEDQGIYTCVATNIL 523 Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 G E+ + L++ ++ GPED V + GS CRV DP + + + Sbjct: 524 GKVEAQV-RLEVKDPTRIVRGPEDQVVKRGSMPRLHCRVKHDPTLKLTVTWLKDDAPLYI 582 Query: 247 G-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293 G R+K DDG L + V D+G+Y+C A + SA YLTV P Sbjct: 583 GNRMKKEDDG-LTIYGVAEKDQGDYTCVASTELDKDSAKAYLTVLALP 629 Score = 120 bits (290), Expect = 2e-25 Identities = 132/522 (25%), Positives = 210/522 (40%), Gaps = 44/522 (8%) Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175 S+ +G ++LEC+ G P P++ W K G L G +++ + L I + + D+ Sbjct: 271 SQMVLRGVDLLLECIAS-GVPAPDIMWYKKGGELPA-GKTKLENFNKA-LRISNVSEEDS 327 Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235 G Y C+A N G+ I+ +++ PY + P++++ G CR G+P P + W Sbjct: 328 GEYFCLASNKMGSIRHTIS-VRVKAAPYWLDEPQNLILAPGEDGRLVCRANGNPKPSIQW 386 Query: 236 RRSAGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293 + G+ P +V D + D I Y C A N G + A+ +++V D P Sbjct: 387 LVNGEPIEGSPPNPSREVAGDTIVFRDTQI-GSSAVYQCNASNEHGYLLANAFVSVLDVP 445 Query: 294 SINLSPNS--VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 L+P + + V N R C G P PT+ W G ++ G K H Sbjct: 446 PRILAPRNQLIKVIQYNRTRLDCPFFGSPIPTLRWFKNGQGNMLDGG--NYKAHENGS-- 501 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411 L ++ K D + C A N G + +L V + P I GP +Q + Sbjct: 502 ----LEMSMARKED-QGIYTCVATNILGKVEAQVRLEV-----KDPTRIVRGPEDQVVKR 551 Query: 412 KSMAVFPCTAICTP--EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469 SM C P + + W + L +R +DG L + + + D G YTCVA Sbjct: 552 GSMPRLHCRVKHDPTLKLTVTWLKDDAPLYIGNRMKKEDDG-LTIYGVAEKDQGDYTCVA 610 Query: 470 SSRHGKYVWSGALLVDS-PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNN 528 S+ K L V + PI P A+ P P ++ + SV L+W + Sbjct: 611 STELDKDSAKAYLTVLALPITP-------AEKPERPDRPRDLELSDLAERSVKLTWIPGD 663 Query: 529 KIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVR 588 +S I Y V+ F + W +R + + SL P + Y F V Sbjct: 664 D-NNSPITDYIVQ-FEEDRFQPGT-------WHNHSRYPGNVNSALLSLSPYVNYQFRVI 714 Query: 589 TENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNI 630 N G S PS S+ + TGV + +NN+ Sbjct: 715 AVNDVGSSLPSMPSERYQTSGARPEI-NPTGVQGAGTQKNNM 755 Score = 112 bits (270), Expect = 5e-23 Identities = 94/348 (27%), Positives = 149/348 (42%), Gaps = 21/348 (6%) Query: 23 VARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAG 81 V R L C A G P+P I WYK GG L T LR ++ D+G Sbjct: 274 VLRGVDLLLECIASGVPAPDIMWYKKGGELPAGKTKLENFNKA----LRISNVS-EEDSG 328 Query: 82 VYWCEATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNV 140 Y+C A+N G+ R T+ V V + L EP++ A G+ L C G+P+P++ Sbjct: 329 EYFCLASNKMGSIRH---TISVRVKAAPYWLDEPQNLILAPGEDGRLVCRA-NGNPKPSI 384 Query: 141 YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200 W NG+ + + V G +V +D + + YQC A N G + + + Sbjct: 385 QWLVNGEPIEGSPPNPSREVAGDTIVFRDTQIGSSAVYQCNASNEHGYLLANAFVSVLDV 444 Query: 201 KPYLITGPEDVVAQTGSSVT-FQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL 259 P ++ ++ + T C G P+P + W ++ G + G K ++GSL + Sbjct: 445 PPRILAPRNQLIKVIQYNRTRLDCPFFGSPIPTLRWFKNGQGNMLDGGNYKAHENGSLEM 504 Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGR 319 D+G Y+C A N +G V A L V DP I P V+ G++ R C Sbjct: 505 SMARKEDQGIYTCVATNILGKVEAQVRLEVKDPTRIVRGPEDQVVKRGSMPRLHCRVKHD 564 Query: 320 P--EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365 P + T+ W + I M ++ DG+T+ + + D+ D Sbjct: 565 PTLKLTVTWLKDDAPLYIGNRMKKED-------DGLTIYGVAEKDQGD 605 Score = 61.3 bits (142), Expect = 2e-07 Identities = 50/160 (31%), Positives = 72/160 (45%), Gaps = 9/160 (5%) Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQ---DARQTD-AGR 177 D + +EC +G+P P W +NG+ D ++ + G LVI R D G Sbjct: 56 DNIFIEC-EAKGNPVPTFSWTRNGKFFNVAKDPKVSMRRRSGTLVIDFHGGGRPDDYEGE 114 Query: 178 YQCIARNAAGTRESAIATLKIHIKPYLITGPEDVV-AQTGSSVTFQCR-VGGDPLPDVLW 235 YQC ARN GT S+ L++ P DV+ G+ ++ QC G P P + W Sbjct: 115 YQCFARNDYGTALSSKIHLQVSRSPLWPKEKVDVIEVDEGAPLSLQCNPPPGLPPPVIFW 174 Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILAD-EGEYSCEA 274 S+ RV +G L NV+L D + +YSC A Sbjct: 175 MSSSMEPIHQDKRVSQGQNGDLYFSNVMLQDAQTDYSCNA 214 Score = 60.9 bits (141), Expect = 2e-07 Identities = 53/183 (28%), Positives = 75/183 (40%), Gaps = 14/183 (7%) Query: 10 EAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGL 66 + P I +Q + D V + C A G+P P W + G V D S+ G Sbjct: 38 QPPTITKQSVKDYIVDPRDNIFIECEAKGNPVPTFSWTRNGKFFNVAKDPKVSMRRRSGT 97 Query: 67 FFLRATHGRVHSD-AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA----Q 121 + G D G Y C A N YGTA S + +H+ V R L P+ K + Sbjct: 98 LVIDFHGGGRPDDYEGEYQCFARNDYGTALS--SKIHLQVSRSP--LWPKEKVDVIEVDE 153 Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQC 180 G + L+C PP G P P ++W + + D R+ G+L + DA Y C Sbjct: 154 GAPLSLQCNPPPGLPPPVIFWMSSSMEPIHQ-DKRVSQGQNGDLYFSNVMLQDAQTDYSC 212 Query: 181 IAR 183 AR Sbjct: 213 NAR 215 Score = 52.0 bits (119), Expect = 1e-04 Identities = 66/292 (22%), Positives = 115/292 (39%), Gaps = 26/292 (8%) Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLD-DGSLRLD--NVIL 264 +D + ++ +C G+P+P W R+ N+ +V + G+L +D Sbjct: 48 KDYIVDPRDNIFIECEAKGNPVPTFSWTRNGKFFNVAKDPKVSMRRRSGTLVIDFHGGGR 107 Query: 265 AD--EGEYSCEAENSVG-AVSASGYLTVYDPPSINLSP-NSVNVESGNVARFTCTAT-GR 319 D EGEY C A N G A+S+ +L V P + + V+ G C G Sbjct: 108 PDDYEGEYQCFARNDYGTALSSKIHLQVSRSPLWPKEKVDVIEVDEGAPLSLQCNPPPGL 167 Query: 320 PEPTMFWSVEGNRTI-----IFPGMSRDKYHATAVF-DGVTVLTIN------DTDKNDSR 367 P P +FW I + G + D Y + + D T + N T + + Sbjct: 168 PPPVIFWMSSSMEPIHQDKRVSQGQNGDLYFSNVMLQDAQTDYSCNARFHFTHTIQQKNP 227 Query: 368 NTIVCSAVNYAGSSFVRGKLTVTS----DDDRPPPIITNGPSNQTLPIKSM-AVFPCTAI 422 T+ + +R + S + P + G S+ + ++ + + C A Sbjct: 228 YTLKVKTKKPHNETSLRNHTDMYSARGVTETTPSFMYPYGTSSSQMVLRGVDLLLECIAS 287 Query: 423 CTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 P P I WY +G L + + L + ++ + DSG Y C+AS++ G Sbjct: 288 GVPAPDIMWYKKGGELPAGKTKLENFNKALRISNVSEEDSGEYFCLASNKMG 339 Score = 37.1 bits (82), Expect = 2.9 Identities = 29/134 (21%), Positives = 61/134 (45%), Gaps = 11/134 (8%) Query: 644 IDSKTIKLMWEILNFYYLEGLFIYFRP--------LDNITIEYEMKTILHSNDVSGFEIT 695 ++S I L W ++ ++G +R L N+ + + + + D + ++ Sbjct: 848 LNSTAIALTWTRVHLDTIQGQLKEYRAYFWRDSSLLKNLWVSKKRQYVSFPGDRNRGIVS 907 Query: 696 SLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPP 755 L Y+ Y+ ++ + +G S + T + VP P + + N +++L+W P Sbjct: 908 RLFPYSNYKLEMVVTNGRGDGPRSEVKEFPTPEGVPSSPRY-LRIRQPNLESINLEWDHP 966 Query: 756 ELQLQNGIITGYNV 769 E NG++TGYN+ Sbjct: 967 EHP--NGVLTGYNL 978 >UniRef50_Q59FX6 Cluster: Protein tyrosine phosphatase, receptor type, sigma isoform 3 variant; n=14; Amniota|Rep: Protein tyrosine phosphatase, receptor type, sigma isoform 3 variant - Homo sapiens (Human) Length = 1560 Score = 122 bits (294), Expect = 6e-26 Identities = 158/612 (25%), Positives = 238/612 (38%), Gaps = 67/612 (10%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI-LPAGGLFF 68 E P I++P D A+ C+A G P P + W K G V S +I Sbjct: 57 EPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAV 116 Query: 69 LRATHGRVHSDAGVYWCEATNSYG--TARSRNATLHVAVLREEFR---LEPESKQSAQGD 123 LR R D VY C A NS G T ++ L L F + P+ K + Sbjct: 117 LRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTR 176 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182 T + C G+P+P + W K+ + + R+ + G L I+ + +TD G+Y+C+A Sbjct: 177 TATMLCAAS-GNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVA 235 Query: 183 RNAAGTRESAIATLKIHIK---PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239 N+AG R S+ A L + ++ P P G +V C G P+P V W + A Sbjct: 236 TNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGA 295 Query: 240 GG----GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295 +MP+GR L L +V D Y+C A +S+G + A +TV P Sbjct: 296 EDLTPEDDMPVGR------NVLELTDV--KDSANYTCVAMSSLGVIEAVAQITVKSLPK- 346 Query: 296 NLSPNSVNVESGNVARFTCT-ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354 +P + V T T +G P+P ++ +E + S+D + T Sbjct: 347 --APGTPMVTENTATSITITWDSGNPDPVSYYVIE------YKSKSQDGPYQIKEDITTT 398 Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414 +I N S I SAVN G + VT ++ P + L +M Sbjct: 399 RYSIGGLSPN-SEYEIWVSAVNSIGQG-PPSESVVTRTGEQAPASAPRNVQARMLSATTM 456 Query: 415 AVFPCTAICTPEPIIAWY-----FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469 V P +I Y E E + N +++ +D L D TYT Sbjct: 457 IV-QWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDE-TYTV-- 512 Query: 470 SSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529 V + + D P++ I + +PG P ++TS+TLSWS + Sbjct: 513 ------RVLAFTSVGDGPLSDPI---QVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQ 563 Query: 530 IGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRT 589 SI+ Y E+ RE G R T YVV+ L P Y F + Sbjct: 564 ---ESIIKY--ELLFREGDHGREVGRTFD---------PTTSYVVEDLKPNTEYAFRLAA 609 Query: 590 ENSHGLSGPSPV 601 + GL +PV Sbjct: 610 RSPQGLGAFTPV 621 Score = 103 bits (247), Expect = 3e-20 Identities = 161/670 (24%), Positives = 255/670 (38%), Gaps = 90/670 (13%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LR 258 P I P+D + +G +F C+ GDP P V W + N D+ + LR Sbjct: 59 PRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLR 118 Query: 259 LDNVILA-DEGEYSCEAENSVGAVSASGYLTVYDP-------PSINLSPNSVNVESGNVA 310 + + DE Y C A+NSVG ++ LTV P+I++ P VE A Sbjct: 119 IQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTA 178 Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370 C A+G P+P + W + + P S + G L I +++ D + Sbjct: 179 TMLCAASGNPDPEITWFKDF--LPVDPSASNGRIKQLR--SGA--LQIESSEETD-QGKY 231 Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA 430 C A N AG + P S++ +P ++ + C A+ +P P + Sbjct: 232 ECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMPGGNVNI-TCVAVGSPMPYVK 290 Query: 431 WYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490 W E L V G VL+ D DS YTCVA S G Sbjct: 291 WMQGAEDLTPEDDMPV---GRNVLELTDVKDSANYTCVAMSSLGV--------------- 332 Query: 491 NIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSG 550 I V SLP P P+ T TS+T++W N + Y +E S+ Sbjct: 333 -IEAVAQITVKSLPKAPGTPMVTENTATSITITWDSGNP---DPVSYYVIEYKSK----- 383 Query: 551 NNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDD 610 + G I + T Y + L P Y V NS G GP S G+ Sbjct: 384 -----SQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIG-QGPPSESVVTRTGEQ 437 Query: 611 SNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRP 670 + + + + R T IV+ E P++ + + + +Y +E P Sbjct: 438 APA-----SAPRNVQARMLSATTMIVQWEE--PVEPNGLIRGYRV--YYTMEPE----HP 484 Query: 671 LDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDV 730 + N ++ + +D + SL + Y ++ F +G S+ +T V Sbjct: 485 VGN----WQKHNV---DDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGV 537 Query: 731 PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH 790 P G P+N+ + T++ L WSPP Q II Y ++ D + T Sbjct: 538 P-GQPMNLRAEARSETSITLSWSPPR---QESIIK-YELLFREGDHGRE-----VGRTFD 587 Query: 791 QATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSI 850 TS ++ +L Y+ ++AA + GLG F+ V R L +S P N +V + Sbjct: 588 PTTSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVV------RQRTLQSIS--PKNFKVKM 639 Query: 851 VAGDFVMETW 860 + V+ +W Sbjct: 640 IMKTSVLLSW 649 >UniRef50_Q4RVZ3 Cluster: Chromosome 9 SCAF14991, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 9 SCAF14991, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 882 Score = 122 bits (293), Expect = 8e-26 Identities = 103/329 (31%), Positives = 142/329 (43%), Gaps = 24/329 (7%) Query: 25 RHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVY 83 R Q L C G P+P + W + G + S T + + L+F + SD G Y Sbjct: 17 RGQTLELECIVQGLPTPKVSWLRRDGEMSESRTSKEMFDRR-LYFNNISE----SDGGEY 71 Query: 84 WCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSPEPNVYW 142 C A NS G T V V + + P S+ A G+TV L+C G P P + W Sbjct: 72 QCIAENSQGKIVH---TYTVTVEASPYWINAPASQLYAPGETVKLDCQAD-GIPPPTITW 127 Query: 143 KKNGQTLLFDG-DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201 NG L + R L D G+L+++D D YQC A N GT + I + Sbjct: 128 TVNGVPLSATAVEPRRLLTDSGSLILKDVSFGDTAIYQCQASNKHGTILTNTNVYVIELP 187 Query: 202 PYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLR 258 P ++T ED T G +C G P P V W S+ + RV +L +G L Sbjct: 188 PQILT--EDGSTYTFVEGQKAVLECETFGSPKPKVTWESSSTSLPLADPRVNLLTNGGLE 245 Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATG 318 + NV DEG Y+C +NS VS S L V + I P ++ ++ G A FTC Sbjct: 246 VSNVSHDDEGIYTCSIQNS--NVSVSAELEVLNRTVILSPPQALRMQPGKTAIFTCMYIT 303 Query: 319 RPE---PTMFWSVEGNRTIIFPGMSRDKY 344 P+ P + W N IF S +KY Sbjct: 304 DPKLHSPVLQW--RKNDQKIFESHSDEKY 330 Score = 105 bits (252), Expect = 7e-21 Identities = 82/292 (28%), Positives = 129/292 (44%), Gaps = 18/292 (6%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSDTHRSILP 62 VT +PY I P A + L+C+A G P P I W GV + R + Sbjct: 88 VTVEASPYWINAPASQLYAPGETVKLDCQADGIPPPTITWTVNGVPLSATAVEPRRLLTD 147 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS-AQ 121 +G L + G D +Y C+A+N +GT + N ++V L + E S + + Sbjct: 148 SGSLILKDVSFG----DTAIYQCQASNKHGTILT-NTNVYVIELPPQILTEDGSTYTFVE 202 Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181 G VLEC GSP+P V W+ + +L D R++L+ G L + + D G Y C Sbjct: 203 GQKAVLEC-ETFGSPKPKVTWESSSTSLPL-ADPRVNLLTNGGLEVSNVSHDDEGIYTCS 260 Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP---LPDVLWRRS 238 +N + S A L++ + +++ P+ + Q G + F C DP P + WR++ Sbjct: 261 IQN---SNVSVSAELEVLNRTVILSPPQALRMQPGKTAIFTCMYITDPKLHSPVLQWRKN 317 Query: 239 AGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 K +G L + NV DEG Y+C+ + AS LT+ Sbjct: 318 DQKIFESHSDEKYTFEGPDLIISNVEPGDEGVYTCQIITKLDMAEASSNLTL 369 Score = 94.3 bits (224), Expect = 2e-17 Identities = 76/265 (28%), Positives = 109/265 (41%), Gaps = 14/265 (5%) Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV-KVLDDGSLRLDNVI 263 I G A G ++ +C V G P P V W R G M R K + D L +N+ Sbjct: 7 IGGHSTYHALRGQTLELECIVQGLPTPKVSWLRR--DGEMSESRTSKEMFDRRLYFNNIS 64 Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPT 323 +D GEY C AENS G + + +TV P +P S G + C A G P PT Sbjct: 65 ESDGGEYQCIAENSQGKIVHTYTVTVEASPYWINAPASQLYAPGETVKLDCQADGIPPPT 124 Query: 324 MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383 + W+V G P +S + L + D D+ C A N G+ Sbjct: 125 ITWTVNG-----VP-LSATAVEPRRLLTDSGSLILKDVSFGDTA-IYQCQASNKHGTILT 177 Query: 384 RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNH 442 + V + PP I+T S T AV C +P+P + W +L + + Sbjct: 178 NTNVYVI---ELPPQILTEDGSTYTFVEGQKAVLECETFGSPKPKVTWESSSTSLPLADP 234 Query: 443 RRNVTNDGTLVLKDLDKSDSGTYTC 467 R N+ +G L + ++ D G YTC Sbjct: 235 RVNLLTNGGLEVSNVSHDDEGIYTC 259 Score = 62.9 bits (146), Expect = 5e-08 Identities = 45/180 (25%), Positives = 71/180 (39%), Gaps = 13/180 (7%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPA 63 YV + E T Q A L C GSP P + W L ++D ++L Sbjct: 182 YVIELPPQILTEDGSTYTFVEGQKAVLECETFGSPKPKVTWESSSTSLPLADPRVNLLTN 241 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123 GGL + H D G+Y C NS + + L+ V+ P++ + G Sbjct: 242 GGLEVSNVS----HDDEGIYTCSIQNSNVSVSAELEVLNRTVILS----PPQALRMQPGK 293 Query: 124 TVVLECL---PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180 T + C+ P+ P + W+KN Q + + +G +L+I + D G Y C Sbjct: 294 TAIFTCMYITDPK-LHSPVLQWRKNDQKIFESHSDEKYTFEGPDLIISNVEPGDEGVYTC 352 Score = 50.8 bits (116), Expect = 2e-04 Identities = 45/171 (26%), Positives = 65/171 (38%), Gaps = 18/171 (10%) Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 G C G P P + W + G + + +FD L N+ ++D Sbjct: 18 GQTLELECIVQGLPTPKVSW-------LRRDGEMSESRTSKEMFD--RRLYFNNISESDG 68 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426 C A N G +TV + P N P++Q C A P Sbjct: 69 -GEYQCIAENSQGKIVHTYTVTVEAS-----PYWINAPASQLYAPGETVKLDCQADGIPP 122 Query: 427 PIIAWYFEG---EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 P I W G A RR +T+ G+L+LKD+ D+ Y C AS++HG Sbjct: 123 PTITWTVNGVPLSATAVEPRRLLTDSGSLILKDVSFGDTAIYQCQASNKHG 173 Score = 41.1 bits (92), Expect = 0.18 Identities = 24/87 (27%), Positives = 40/87 (45%), Gaps = 2/87 (2%) Query: 733 GPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQA 792 GPP+++ + + T + L W+PP+ NGI+ GY + + + M + Q Sbjct: 589 GPPMSLVLDSPSETEITLHWTPPD--QPNGILIGYELQYQQIMQSDDSPMQVEDKVNPQT 646 Query: 793 TSLIMTNLTSGVSYSVQIAAETIIGLG 819 TSL++ L Y + T GLG Sbjct: 647 TSLMLKGLDRHSHYRFYLMGRTAAGLG 673 Score = 39.5 bits (88), Expect = 0.55 Identities = 15/76 (19%), Positives = 40/76 (52%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753 + + ++ +E + ++ G + + + +DVP PP+++ + + N+TT+ + W+ Sbjct: 462 VNDTQNFSAFEIKVQAVNERGRGPEPDPVIGYSGEDVPLEPPLDVGILMENSTTIKVTWA 521 Query: 754 PPELQLQNGIITGYNV 769 P + + G + GY + Sbjct: 522 PIDKETVRGRLLGYKI 537 Score = 35.9 bits (79), Expect = 6.7 Identities = 23/113 (20%), Positives = 53/113 (46%), Gaps = 7/113 (6%) Query: 495 FRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTP 554 F + D++ +PGPP + + ++T +TL W+ ++ + ++GY+++ ++ + +++P Sbjct: 579 FSSYDIAVIPGPPMSLVLDSPSETEITLHWTPPDQ-PNGILIGYELQY--QQIMQSDDSP 635 Query: 555 RNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607 V T ++K L Y F + + GL P + T+ Sbjct: 636 MQVEDKV----NPQTTSLMLKGLDRHSHYRFYLMGRTAAGLGEPIKKDGATTL 684 >UniRef50_P13591 Cluster: Neural cell adhesion molecule 1, 140 kDa isoform precursor; n=109; Euteleostomi|Rep: Neural cell adhesion molecule 1, 140 kDa isoform precursor - Homo sapiens (Human) Length = 848 Score = 122 bits (293), Expect = 8e-26 Identities = 111/429 (25%), Positives = 177/429 (41%), Gaps = 28/429 (6%) Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPE 137 DAG+Y C T G+ AT++V + ++ F+ P ++ +G+ V+ C P Sbjct: 90 DAGIYKCVVTGEDGS--ESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLP- 146 Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197 P + WK G+ ++ D R ++ L I+ ++TD G Y+C R A E ++ Sbjct: 147 PTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILA-RGEINFKDIQ 205 Query: 198 IHIK-PYLITGPEDVV---AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL- 252 + + P I +++V A G SVT C G P P + W + K + Sbjct: 206 VIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIF 265 Query: 253 -DDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310 DD S L + V DE EY C AEN G A+ +L V+ P I N +E Sbjct: 266 SDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQV 325 Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370 TC A+G P P++ W R I + D + V+ LT+ D+ Sbjct: 326 TLTCEASGDPIPSITWRT-STRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDA-GEY 383 Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPI-ITNGPSNQTLPIKSMAVFPCTAICTPEPII 429 +C+A N G L V P+ + NQ C P I Sbjct: 384 ICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQ-------VNITCEVFAYPSATI 436 Query: 430 AWYFEGEALIQNHRRNVTNDGT-----LVLKDLDKSDSGTYTCVASSRHGKYVWSGALL- 483 +W+ +G+ L ++ N+ T L + ++D G Y C A +R G+ L+ Sbjct: 437 SWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQ 496 Query: 484 VDSPINPNI 492 D+P +P+I Sbjct: 497 ADTPSSPSI 505 Score = 101 bits (241), Expect = 2e-19 Identities = 96/380 (25%), Positives = 147/380 (38%), Gaps = 30/380 (7%) Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLV----DGGNLVIQ 168 P + + G++ C + + ++ W NG+ L R+ +V L I Sbjct: 26 PSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLT-PNQQRISVVWNDDSSSTLTIY 84 Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228 +A DAG Y+C+ G+ A +KI K P + G C V Sbjct: 85 NANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSS 144 Query: 229 PLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAE-NSVGAVSASGY 286 P ++W+ + R VL + L++ + DEG Y CE + G ++ Sbjct: 145 LPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDI 204 Query: 287 LTVYD-PPSINLSPNSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDK 343 + + PP+I N VN + G C A G PEPTM W+ +G + I +K Sbjct: 205 QVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQ--IEQEEDDEK 262 Query: 344 YHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG 403 Y D + LTI DKND +C A N AG L V + P IT Sbjct: 263 Y---IFSDDSSQLTIKKVDKNDEAE-YICIAENKAGEQDATIHLKVFA-----KPKITYV 313 Query: 404 PSNQTLPIKSMAVFPCTAICTPEPIIAW------YFEGEALIQNHR--RNVTNDGTLVLK 455 + + ++ C A P P I W E + H R+ +L LK Sbjct: 314 ENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLK 373 Query: 456 DLDKSDSGTYTCVASSRHGK 475 + +D+G Y C AS+ G+ Sbjct: 374 SIQYTDAGEYICTASNTIGQ 393 Score = 71.3 bits (167), Expect = 1e-10 Identities = 81/303 (26%), Positives = 122/303 (40%), Gaps = 30/303 (9%) Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGLFFLRATHGRV 76 ++ T Q TL C A G P P + W K G + D + I + T +V Sbjct: 221 VNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDS---SQLTIKKV 277 Query: 77 -HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGS 135 +D Y C A N G ++AT+H+ V + E++ + + + V G Sbjct: 278 DKNDEAEYICIAENKAG---EQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGD 334 Query: 136 PEPNVYWKKNGQTL-----LFDGDS--RMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188 P P++ W+ + + + DG R H +L ++ + TDAG Y C A N G Sbjct: 335 PIPSITWRTSTRNISSEEKTLDGHMVVRSH-ARVSSLTLKSIQYTDAGEYICTASNTIG- 392 Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP--- 245 ++S L++ P L GP V G+ V C V P + W R G +P Sbjct: 393 QDSQSMYLEVQYAPKL-QGPVAVYTWEGNQVNITCEVFAYPSATISWFRD--GQLLPSSN 449 Query: 246 LGRVKVLDDGSLRLDNVILADE---GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302 +K+ + S V E G Y+C A N +G S L D PS SP+ Sbjct: 450 YSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPS---SPSID 506 Query: 303 NVE 305 VE Sbjct: 507 QVE 509 >UniRef50_UPI0000DB6DF8 Cluster: PREDICTED: similar to leucine-rich repeats and immunoglobulin-like domains 3; n=1; Apis mellifera|Rep: PREDICTED: similar to leucine-rich repeats and immunoglobulin-like domains 3 - Apis mellifera Length = 909 Score = 121 bits (292), Expect = 1e-25 Identities = 90/304 (29%), Positives = 130/304 (42%), Gaps = 18/304 (5%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIR--WYKGGVLVVSD--------THRSIL 61 P IIE+P + TL CRA + + W + + D T + Sbjct: 479 PRIIEEPKSQMGIKGDNVTLVCRATSTAIARLHFTWKHDNIEINDDNLQINTDSTENGVT 538 Query: 62 PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121 A + L H++AG Y C TN+YGT S A L + + F P + Sbjct: 539 EATSILHLTNV---THANAGKYQCMVTNTYGTTYSAKAKLSILIY-PSFSKIPHDIRVIA 594 Query: 122 GDTVVLECLPPRGSPEPNVYWKKNG-QTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQ 179 G T LEC G P P + W+K+G + RMH++ + L I D + D+G Y Sbjct: 595 GSTARLEC-SAEGQPSPQIAWQKDGGNDFPAARERRMHMMPTDDVLFIVDVKTADSGVYS 653 Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239 C A+N AG A ATL I P + E+ G S+ +C G P P + WR++ Sbjct: 654 CTAQNLAGLIV-ANATLTILETPSFVKPMENKEVTVGGSIVLECMASGMPRPKLSWRKNG 712 Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299 +D L + + ++D G Y CE NS+G+V + +LTV P SP Sbjct: 713 NPLLATERHFFTAEDQLLIIVDTRISDAGSYECEMSNSLGSVVGASHLTVKPAPISTPSP 772 Query: 300 NSVN 303 SVN Sbjct: 773 GSVN 776 Score = 113 bits (272), Expect = 3e-23 Identities = 90/306 (29%), Positives = 133/306 (43%), Gaps = 27/306 (8%) Query: 113 EPESKQSAQGDTVVLECLPPRGS-PEPNVYWKK-----NGQTLLFDGDSRMHLVDGGNLV 166 EP+S+ +GD V L C + + WK N L + DS + V + Sbjct: 484 EPKSQMGIKGDNVTLVCRATSTAIARLHFTWKHDNIEINDDNLQINTDSTENGVTEATSI 543 Query: 167 IQ--DARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR 224 + + +AG+YQC+ N GT SA A L I I P P D+ GS+ +C Sbjct: 544 LHLTNVTHANAGKYQCMVTNTYGTTYSAKAKLSILIYPSFSKIPHDIRVIAGSTARLECS 603 Query: 225 VGGDPLPDVLWRRSAGGGNMPLGRVKVL----DDGSLRLDNVILADEGEYSCEAENSVGA 280 G P P + W++ GG + P R + + D L + +V AD G YSC A+N G Sbjct: 604 AEGQPSPQIAWQKD-GGNDFPAARERRMHMMPTDDVLFIVDVKTADSGVYSCTAQNLAGL 662 Query: 281 VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340 + A+ LT+ + PS + V G C A+G P P + W GN P ++ Sbjct: 663 IVANATLTILETPSFVKPMENKEVTVGGSIVLECMASGMPRPKLSWRKNGN-----PLLA 717 Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII 400 +++ TA +L I DT +D+ + C N GS LTV +P PI Sbjct: 718 TERHFFTAEDQ---LLIIVDTRISDA-GSYECEMSNSLGSVVGASHLTV-----KPAPIS 768 Query: 401 TNGPSN 406 T P + Sbjct: 769 TPSPGS 774 Score = 98.3 bits (234), Expect = 1e-18 Identities = 84/302 (27%), Positives = 126/302 (41%), Gaps = 24/302 (7%) Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV--LWRRS---AGGGNMPLGRVK----V 251 KP +I P+ + G +VT CR + + W+ N+ + V Sbjct: 478 KPRIIEEPKSQMGIKGDNVTLVCRATSTAIARLHFTWKHDNIEINDDNLQINTDSTENGV 537 Query: 252 LDDGS-LRLDNVILADEGEYSCEAENSVGAV-SASGYLTVYDPPSINLSPNSVNVESGNV 309 + S L L NV A+ G+Y C N+ G SA L++ PS + P+ + V +G+ Sbjct: 538 TEATSILHLTNVTHANAGKYQCMVTNTYGTTYSAKAKLSILIYPSFSKIPHDIRVIAGST 597 Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369 AR C+A G+P P + W +G FP + H D VL I D DS Sbjct: 598 ARLECSAEGQPSPQIAWQKDGGND--FPAARERRMHMMPTDD---VLFIVDVKTADS-GV 651 Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429 C+A N AG LT+ P+ N+ + + V C A P P + Sbjct: 652 YSCTAQNLAGLIVANATLTILETPSFVKPM-----ENKEVTVGGSIVLECMASGMPRPKL 706 Query: 430 AWYFEGEALIQNHRRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV-DSP 487 +W G L+ R T D L++ D SD+G+Y C S+ G V + L V +P Sbjct: 707 SWRKNGNPLLATERHFFTAEDQLLIIVDTRISDAGSYECEMSNSLGSVVGASHLTVKPAP 766 Query: 488 IN 489 I+ Sbjct: 767 IS 768 Score = 37.9 bits (84), Expect = 1.7 Identities = 26/84 (30%), Positives = 37/84 (44%), Gaps = 3/84 (3%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P ++ + V L C A G P P + W K G +++ T R A + Sbjct: 673 ETPSFVKPMENKEVTVGGSIVLECMASGMPRPKLSWRKNGNPLLA-TERHFFTAEDQLLI 731 Query: 70 RATHGRVHSDAGVYWCEATNSYGT 93 R+ SDAG Y CE +NS G+ Sbjct: 732 -IVDTRI-SDAGSYECEMSNSLGS 753 >UniRef50_UPI00015B6341 Cluster: PREDICTED: similar to KLG; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to KLG - Nasonia vitripennis Length = 1117 Score = 120 bits (289), Expect = 2e-25 Identities = 90/279 (32%), Positives = 128/279 (45%), Gaps = 15/279 (5%) Query: 18 PLDVTVARHQPATLNC--RAGGSPSPAIRWYKGGVLVVSDT---HRSIL-PAGGLFFLRA 71 P V+V +PATL C RA P +RW + G ++S +R + PAG L + Sbjct: 421 PKPVSVMEDEPATLTCSFRAMEPPITQVRWLRDGEALLSKDGVRYRIVEEPAGNLSLIFK 480 Query: 72 THGRVHSDAGVYWCE-ATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130 + D G Y CE T + RS A L V + +F EP +++ + + C Sbjct: 481 NVQLI--DRGNYVCEIVTKGFSPVRSAPAALSVEE-KLKFSPEPVNRKLELNSSPKISC- 536 Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190 +GS W KNG F R L G L + D G Y C+A N+ G + Sbjct: 537 KAQGSTPVTFKWYKNGADS-FPKHVRDEL--NGTLHFNGVLEEDKGNYTCVASNSQGQIK 593 Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250 I + + I P PE+V A GSSV C GDP P + W + + N+ R + Sbjct: 594 HTIK-IDVVISPKFTIKPENVTAIEGSSVLLHCAAEGDPKPAIQWDKDSRMNNLNGDRFE 652 Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 V+ +GSL + V L+DEG+Y C A NS G G+L+V Sbjct: 653 VMANGSLHIKEVYLSDEGKYGCTAGNSAGLKREEGHLSV 691 Score = 114 bits (275), Expect = 1e-23 Identities = 128/488 (26%), Positives = 194/488 (39%), Gaps = 46/488 (9%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWY---KGGVLVVSDTHRSILP 62 V S E I P V R++PA+ +C + + ++W+ KG + SD RSIL Sbjct: 221 VPSNETATIKLVPQKAIVRRYEPASFSCVFDNADN--VQWFFEDKGPI--ESDDERSILD 276 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVL----REEFRLEPESKQ 118 G L L+A G Y C + T + A L +A L E F E + Sbjct: 277 NGTLVVLKAEDRH----KGYYACHGLRA-DTVQVYAAELQIAYLYNLTSESFEPPLEDRL 331 Query: 119 SAQGDTVVLE--CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAG 176 + G+ L+ CL P G P P ++W++ ++ D + + D +V + R D G Sbjct: 332 AVVGENQELQVSCLAPGGLPTPKLFWREPQGRIVSD-TGPVRVQDDTLIVAKARRNADEG 390 Query: 177 RYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC--RVGGDPLPDVL 234 Y C A N AG ++ + + + L + P+ V T C R P+ V Sbjct: 391 NYTCHAENMAGATQATVRIV-VSWPAELKSSPKPVSVMEDEPATLTCSFRAMEPPITQVR 449 Query: 235 WRRSAGGGNMPLG-RVKVLDD--GSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTV 289 W R G R +++++ G+L L NV L D G Y CE + S + Sbjct: 450 WLRDGEALLSKDGVRYRIVEEPAGNLSLIFKNVQLIDRGNYVCEIVTKGFSPVRSAPAAL 509 Query: 290 YDPPSINLSPNSVN--VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347 + SP VN +E + + +C A G T W G + FP RD+ + T Sbjct: 510 SVEEKLKFSPEPVNRKLELNSSPKISCKAQGSTPVTFKWYKNGADS--FPKHVRDELNGT 567 Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407 F+GV + + C A N G K+ V P T P N Sbjct: 568 LHFNGVL---------EEDKGNYTCVASNSQGQIKHTIKIDVVIS-----PKFTIKPENV 613 Query: 408 TLPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYT 466 T S + C A P+P I W + + R V +G+L +K++ SD G Y Sbjct: 614 TAIEGSSVLLHCAAEGDPKPAIQWDKDSRMNNLNGDRFEVMANGSLHIKEVYLSDEGKYG 673 Query: 467 CVASSRHG 474 C A + G Sbjct: 674 CTAGNSAG 681 Score = 102 bits (244), Expect = 7e-20 Identities = 100/389 (25%), Positives = 161/389 (41%), Gaps = 28/389 (7%) Query: 16 EQPLD---VTVARHQPATLNCRA-GGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 E PL+ V +Q ++C A GG P+P + W + +VSDT + L +A Sbjct: 324 EPPLEDRLAVVGENQELQVSCLAPGGLPTPKLFWREPQGRIVSDTGPVRVQDDTLIVAKA 383 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVL-REEFRLEPESKQSAQGDTVVLEC- 129 R ++D G Y C A N G + AT+ + V E + P+ + + L C Sbjct: 384 ---RRNADEGNYTCHAENMAGATQ---ATVRIVVSWPAELKSSPKPVSVMEDEPATLTCS 437 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD--GGNL--VIQDARQTDAGRYQC-IARN 184 P V W ++G+ LL R +V+ GNL + ++ + D G Y C I Sbjct: 438 FRAMEPPITQVRWLRDGEALLSKDGVRYRIVEEPAGNLSLIFKNVQLIDRGNYVCEIVTK 497 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 SA A L + K P + + SS C+ G W ++ G + Sbjct: 498 GFSPVRSAPAALSVEEKLKFSPEPVNRKLELNSSPKISCKAQGSTPVTFKWYKN-GADSF 556 Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304 P V+ +G+L + V+ D+G Y+C A NS G + + + V P + P +V Sbjct: 557 PK-HVRDELNGTLHFNGVLEEDKGNYTCVASNSQGQIKHTIKIDVVISPKFTIKPENVTA 615 Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 G+ C A G P+P + W + ++ D++ A +G L I + + Sbjct: 616 IEGSSVLLHCAAEGDPKPAIQWDKDSRMN----NLNGDRFEVMA--NG--SLHIKEVYLS 667 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393 D C+A N AG G L+V + D Sbjct: 668 D-EGKYGCTAGNSAGLKREEGHLSVRAGD 695 Score = 62.5 bits (145), Expect = 7e-08 Identities = 145/636 (22%), Positives = 239/636 (37%), Gaps = 67/636 (10%) Query: 13 YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRAT 72 Y P D V Q TL C A W G + R P G + Sbjct: 38 YFTVSPSDHQVVEGQSVTLRCEAEPGAPVRYSWKIDGQPLAPSPRRH--PKSGNLLISRV 95 Query: 73 HGRVHSDAGVYWCEATN--SYGTARSRNATLHVAVLRE-EFRLE-PESKQSAQ-GDTVVL 127 + + D+G + C ATN S + S A + + + E +L+ P+ + + G V L Sbjct: 96 NRML--DSGSFVCVATNEKSGDSIESSPAKIDIQWISEASVQLQQPKLAPNIRAGGKVEL 153 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 C GS E W +N +++ + R+ + L+IQ+A D G Y+C+ARN AG Sbjct: 154 RCHVD-GSGELKYEWFRNTKSVA--PNDRVEM-KRNLLLIQEASPEDNGVYRCLARNQAG 209 Query: 188 TRESAIATLKIHIKPYLITG-----PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242 S +A I P T P+ + + +F C D +V W G Sbjct: 210 A--SPLAHSYPLIVPSNETATIKLVPQKAIVRRYEPASFSCVF--DNADNVQWFFEDKGP 265 Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEA--ENSVGAVSASGYLT-VYDPPSINLSP 299 +LD+G+L + +G Y+C ++V +A + +Y+ S + P Sbjct: 266 IESDDERSILDNGTLVVLKAEDRHKGYYACHGLRADTVQVYAAELQIAYLYNLTSESFEP 325 Query: 300 ----NSVNVESGNVARFTCTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354 V + +C A G P P +FW R + G R V D Sbjct: 326 PLEDRLAVVGENQELQVSCLAPGGLPTPKLFWREPQGRIVSDTGPVR-------VQD--D 376 Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414 L + +N C A N AG++ ++ V+ P + + P ++ Sbjct: 377 TLIVAKARRNADEGNYTCHAENMAGATQATVRIVVSW-----PAELKSSPKPVSVMEDEP 431 Query: 415 AVFPCTAICTPEPI--IAWYFEGEALIQNH--RRNVTNDG----TLVLKDLDKSDSGTYT 466 A C+ PI + W +GEAL+ R + + +L+ K++ D G Y Sbjct: 432 ATLTCSFRAMEPPITQVRWLRDGEALLSKDGVRYRIVEEPAGNLSLIFKNVQLIDRGNYV 491 Query: 467 CVASSRHGKYVWS--GALLVDSPINPNIH-FFRAADVSSLPGPPTKPITHNVTDTSVTLS 523 C ++ V S AL V+ + + R +++S P K T VT Sbjct: 492 CEIVTKGFSPVRSAPAALSVEEKLKFSPEPVNRKLELNSSPKISCKA----QGSTPVTFK 547 Query: 524 WSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRG--WVVIARRVHQTHYVVKSLIPGI 581 W +N G+ S + V TL N +G V + Q + +K + I Sbjct: 548 WYKN---GADSFPKH-VRDELNGTLHFNGVLEEDKGNYTCVASNSQGQIKHTIKIDVV-I 602 Query: 582 TYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSL-WE 616 + F ++ EN + G S + GD ++ W+ Sbjct: 603 SPKFTIKPENVTAIEGSSVLLHCAAEGDPKPAIQWD 638 Score = 42.7 bits (96), Expect = 0.059 Identities = 34/122 (27%), Positives = 51/122 (41%), Gaps = 11/122 (9%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 +P +P +VT L+C A G P PAI+W K + + R + A G ++ Sbjct: 603 SPKFTIKPENVTAIEGSSVLLHCAAEGDPKPAIQWDKDSRMNNLNGDRFEVMANGSLHIK 662 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV-----LREEFRLEPESKQSAQGDTV 125 + SD G Y C A NS G R H++V R + L+ S TV Sbjct: 663 EVY---LSDEGKYGCTAGNSAGLKREEG---HLSVRAGDGYRSDMELDAAEDGSMMTKTV 716 Query: 126 VL 127 ++ Sbjct: 717 II 718 >UniRef50_Q23991 Cluster: Peroxidasin precursor; n=7; Coelomata|Rep: Peroxidasin precursor - Drosophila melanogaster (Fruit fly) Length = 1535 Score = 120 bits (289), Expect = 2e-25 Identities = 95/302 (31%), Positives = 140/302 (46%), Gaps = 20/302 (6%) Query: 8 SGEAPYIIEQPLDVTVARHQPA--TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 S P+ QP D VA H L+C A G P P I+W+ G ++ T L A G Sbjct: 365 SHSPPHFTHQPHDQIVALHSSGHVLLDCAASGWPQPDIQWFVNGRQLLQSTPSLQLQANG 424 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 L + AG Y CEA NS G+ ++ A + + L E P+S+ G Sbjct: 425 SLILLQPN---QLSAGTYRCEARNSLGSVQA-TARIELKEL-PEILTAPQSQTIKLGKAF 479 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 VLEC G+P P + W+ NG L + + LV+ ARQ AG Y+C A N Sbjct: 480 VLEC-DADGNPLPTIDWQLNGVPLPGNTPDLQLENENTELVVGAARQEHAGVYRCTAHNE 538 Query: 186 AGTRESAIATLKI---HIKPYLITGPEDVVAQTGSSVTFQCRVG--GDPLPDVLWRRSAG 240 G S AT+K+ P L P ++VA TG+++ C+ D L + WR Sbjct: 539 NG-ETSVEATIKVERSQSPPQLAIEPSNLVAITGTTIELPCQADQPEDGL-QISWRHDGR 596 Query: 241 --GGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297 N+ L + ++ GSL + NV + D G Y C+ +N G SAS +T+ + +++L Sbjct: 597 LIDPNVQLAEKYQISGAGSLFVKNVTIPDGGRYECQLKNQFGRASASALVTIRN--NVDL 654 Query: 298 SP 299 +P Sbjct: 655 AP 656 Score = 90.2 bits (214), Expect = 3e-16 Identities = 75/309 (24%), Positives = 130/309 (42%), Gaps = 19/309 (6%) Query: 199 HIKPYLITGPEDVVAQTGSS--VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS 256 H P+ P D + SS V C G P PD+ W + +++ +GS Sbjct: 366 HSPPHFTHQPHDQIVALHSSGHVLLDCAASGWPQPDIQWFVNGRQLLQSTPSLQLQANGS 425 Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316 L L G Y CEA NS+G+V A+ + + + P I +P S ++ G C A Sbjct: 426 LILLQPNQLSAGTYRCEARNSLGSVQATARIELKELPEILTAPQSQTIKLGKAFVLECDA 485 Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376 G P PT+ W + G + PG + D + + T L + + + C+A N Sbjct: 486 DGNPLPTIDWQLNG---VPLPGNTPD----LQLENENTELVVG-AARQEHAGVYRCTAHN 537 Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEG 435 G + V + T+ + + PP + PSN + PC A + + I+W +G Sbjct: 538 ENGETSV--EATIKVERSQSPPQLAIEPSNLVAITGTTIELPCQADQPEDGLQISWRHDG 595 Query: 436 EALIQN----HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPIN-- 489 + N + ++ G+L +K++ D G Y C ++ G+ S + + + ++ Sbjct: 596 RLIDPNVQLAEKYQISGAGSLFVKNVTIPDGGRYECQLKNQFGRASASALVTIRNNVDLA 655 Query: 490 PNIHFFRAA 498 P + R A Sbjct: 656 PGDRYVRIA 664 Score = 86.2 bits (204), Expect = 5e-15 Identities = 70/279 (25%), Positives = 123/279 (44%), Gaps = 16/279 (5%) Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 V+L+C G P+P++ W NG+ LL S + L G+L++ Q AG Y+C ARN Sbjct: 388 VLLDCAAS-GWPQPDIQWFVNGRQLLQSTPS-LQLQANGSLILLQPNQLSAGTYRCEARN 445 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG--GG 242 + G+ + A A +++ P ++T P+ + G + +C G+PLP + W+ + G Sbjct: 446 SLGSVQ-ATARIELKELPEILTAPQSQTIKLGKAFVLECDADGNPLPTIDWQLNGVPLPG 504 Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDPPSINLSP 299 N P +++ ++ L + G Y C A N G S + V PP + + P Sbjct: 505 NTPDLQLE-NENTELVVGAARQEHAGVYRCTAHNENGETSVEATIKVERSQSPPQLAIEP 563 Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS-RDKYHATAVFDGVTVLTI 358 +++ +G C A +PE + S + +I P + +KY G L + Sbjct: 564 SNLVAITGTTIELPCQA-DQPEDGLQISWRHDGRLIDPNVQLAEKYQ----ISGAGSLFV 618 Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397 + D C N G + +T+ ++ D P Sbjct: 619 KNVTIPDG-GRYECQLKNQFGRASASALVTIRNNVDLAP 656 Score = 57.2 bits (132), Expect = 3e-06 Identities = 36/130 (27%), Positives = 57/130 (43%), Gaps = 1/130 (0%) Query: 102 HVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD 161 H + +F + P+ Q A G+ V L C G P + W N Q L + ++ ++ Sbjct: 232 HFKCAKPQFLVAPQDAQVAAGEQVELSC-EVTGLHRPQITWMHNTQELGLEEQTQAEILP 290 Query: 162 GGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTF 221 G+L+ + A +D G YQCIARN G S L ++ + + P D + + Sbjct: 291 SGSLLHRSADTSDMGIYQCIARNEMGALRSQPVRLVVNGGNHPLDSPIDARSNQVWADAG 350 Query: 222 QCRVGGDPLP 231 G PLP Sbjct: 351 TPTHGATPLP 360 Score = 44.0 bits (99), Expect = 0.025 Identities = 24/82 (29%), Positives = 35/82 (42%), Gaps = 1/82 (1%) Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDGSLRL 259 KP + P+D G V C V G P + W + G + ++L GSL Sbjct: 237 KPQFLVAPQDAQVAAGEQVELSCEVTGLHRPQITWMHNTQELGLEEQTQAEILPSGSLLH 296 Query: 260 DNVILADEGEYSCEAENSVGAV 281 + +D G Y C A N +GA+ Sbjct: 297 RSADTSDMGIYQCIARNEMGAL 318 Score = 42.7 bits (96), Expect = 0.059 Identities = 30/94 (31%), Positives = 38/94 (40%), Gaps = 6/94 (6%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG--VLVVSDTHRSILPAGGLFFL 69 P + P D VA + L+C G P I W + + T ILP+G L Sbjct: 238 PQFLVAPQDAQVAAGEQVELSCEVTGLHRPQITWMHNTQELGLEEQTQAEILPSGSLLHR 297 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103 A SD G+Y C A N G RS+ L V Sbjct: 298 SADT----SDMGIYQCIARNEMGALRSQPVRLVV 327 >UniRef50_A7RGM2 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 545 Score = 120 bits (289), Expect = 2e-25 Identities = 110/382 (28%), Positives = 169/382 (44%), Gaps = 26/382 (6%) Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQ 172 ++ + D V LE + G P+P V W G+ + + + R++ + G+ LVI++A Sbjct: 177 AENEVENDAVRLE-VEVTGEPKPVVLWFCEGKPI--EENRRVYTMRDGSTSVLVIENAEL 233 Query: 173 TDAGRYQCIARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231 D Y C A N G E + L P + E GS + V G P P Sbjct: 234 DDEAMYTCKAINDLGEVECSSEMLPTDEAGPKFLQRLELKEVVEGSRTDLEVEVSGKPKP 293 Query: 232 DVLWRRSAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288 V W + G P + + +G +L + N L DEGEY+C A+N VG VS + L Sbjct: 294 VVEWLKD-GELVKPSSLMTLETEGQVHTLTIMNTTLDDEGEYTCIAKNKVGEVSCTAELL 352 Query: 289 VYD---PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345 V + PP + P+S+ + G +A+F +G P P + W +G I PG ++ Sbjct: 353 VEEGMRPPQFIVKPSSLQIMEGKMAKFEARVSGLPGPEVEWLRDGRP--IKPGR---RFQ 407 Query: 346 ATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPS 405 D +VLTI D ND C A + AG +L V D+ PP S Sbjct: 408 IEFEKDR-SVLTIIDAKLND-EGEYTCVATSKAGKDSCSVELLV--DEAVVPPEFVRKIS 463 Query: 406 NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDS 462 N L +A F TP P + WY + + R + +D +LV++D SD+ Sbjct: 464 NIELTEGEIARFDVRITGTPAPEVTWYKDEVPIEDGGRFEIYSDDDKHSLVIRDCALSDT 523 Query: 463 GTYTCVASSRHGKYVWSGALLV 484 G+Y+C A++ G+ G L + Sbjct: 524 GSYSCKATNEAGQASCYGELTI 545 Score = 117 bits (281), Expect = 2e-24 Identities = 133/488 (27%), Positives = 198/488 (40%), Gaps = 60/488 (12%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR--SILPAGGLFFLRATHGRVH 77 D+ V TL GSP P + W+K G V HR + G ++ L R Sbjct: 11 DIEVNEGNTVTLRIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVYTLVIKEAR-G 69 Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC-----LPP 132 SD G Y C+A NS G S + +V VL + P+ +++ + T+ C + Sbjct: 70 SDTGKYLCKAYNSAGEVTS---SCNVDVLHVAPKEPPKFERNLKDITIAEGCSTRFDVQV 126 Query: 133 RGSPEPNVYWKKNGQTLL-FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191 GSPEP V+W NG+ + D +H + +L++ +G+Y C+A N E+ Sbjct: 127 TGSPEPKVFWYHNGKLVQPRDHVDIVHDDEHSSLILMHCPLDLSGKYTCVAENEV---EN 183 Query: 192 AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251 L++ +TG +P P VLW G RV Sbjct: 184 DAVRLEVE-----VTG--------------------EPKPVVLW-FCEGKPIEENRRVYT 217 Query: 252 LDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP--PSINLSPNSVNVES 306 + DGS L ++N L DE Y+C+A N +G V S + D P V Sbjct: 218 MRDGSTSVLVIENAELDDEAMYTCKAINDLGEVECSSEMLPTDEAGPKFLQRLELKEVVE 277 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG-VTVLTINDTDKND 365 G+ +G+P+P + W +G ++ P T +G V LTI +T +D Sbjct: 278 GSRTDLEVEVSGKPKPVVEWLKDGE--LVKPSSL-----MTLETEGQVHTLTIMNTTLDD 330 Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425 C A N G +L V + RPP I PS+ + MA F P Sbjct: 331 -EGEYTCIAKNKVGEVSCTAELLV-EEGMRPPQFIVK-PSSLQIMEGKMAKFEARVSGLP 387 Query: 426 EPIIAWYFEGEALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482 P + W +G + R + + L + D +D G YTCVA+S+ GK S L Sbjct: 388 GPEVEWLRDGRPIKPGRRFQIEFEKDRSVLTIIDAKLNDEGEYTCVATSKAGKDSCSVEL 447 Query: 483 LVDSPINP 490 LVD + P Sbjct: 448 LVDEAVVP 455 Score = 94.7 bits (225), Expect = 1e-17 Identities = 73/269 (27%), Positives = 113/269 (42%), Gaps = 16/269 (5%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 L G P P + W K G LV + ++ G + L + + D G Y C A N Sbjct: 283 LEVEVSGKPKPVVEWLKDGELVKPSSLMTLETEGQVHTLTIMNTTL-DDEGEYTCIAKNK 341 Query: 91 YGTARSRNATLHVAVLR-EEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149 G L +R +F ++P S Q +G E G P P V W ++G+ + Sbjct: 342 VGEVSCTAELLVEEGMRPPQFIVKPSSLQIMEGKMAKFEA-RVSGLPGPEVEWLRDGRPI 400 Query: 150 LFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL--KIHIKPYLIT 206 ++ D L I DA+ D G Y C+A + AG ++ L + + P + Sbjct: 401 KPGRRFQIEFEKDRSVLTIIDAKLNDEGEYTCVATSKAGKDSCSVELLVDEAVVPPEFVR 460 Query: 207 GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDG---SLRLD 260 ++ G F R+ G P P+V W + +P+ GR ++ D SL + Sbjct: 461 KISNIELTEGEIARFDVRITGTPAPEVTWYKD----EVPIEDGGRFEIYSDDDKHSLVIR 516 Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTV 289 + L+D G YSC+A N G S G LT+ Sbjct: 517 DCALSDTGSYSCKATNEAGQASCYGELTI 545 Score = 85.4 bits (202), Expect = 8e-15 Identities = 95/411 (23%), Positives = 161/411 (39%), Gaps = 46/411 (11%) Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---L 165 EF+ + +G+TV L + GSP+P V W K+G+ + R + G L Sbjct: 4 EFKSALRDIEVNEGNTVTLR-IHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVYTL 62 Query: 166 VIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY----LITGPEDVVAQTGSSVTF 221 VI++AR +D G+Y C A N+AG S+ +H+ P +D+ G S F Sbjct: 63 VIKEARGSDTGKYLCKAYNSAGEVTSSCNVDVLHVAPKEPPKFERNLKDITIAEGCSTRF 122 Query: 222 QCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281 +V G P P V W + G P V ++ D ++IL C + Sbjct: 123 DVQVTGSPEPKVFWYHN-GKLVQPRDHVDIVHDDEH--SSLILMH-----CPLD------ 168 Query: 282 SASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341 SG T ++ N V + R TG P+P + W EG Sbjct: 169 -LSGKYTC-------VAENEVE---NDAVRLEVEVTGEPKPVVLWFCEGKPI-------E 210 Query: 342 DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401 + + DG T + + + + D C A+N G ++ T D+ P + Sbjct: 211 ENRRVYTMRDGSTSVLVIENAELDDEAMYTCKAINDLGEVECSSEMLPT--DEAGPKFLQ 268 Query: 402 NGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLD 458 + + S P+P++ W +GE + + + +G TL + + Sbjct: 269 RLELKEVVE-GSRTDLEVEVSGKPKPVVEWLKDGELVKPSSLMTLETEGQVHTLTIMNTT 327 Query: 459 KSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTK 509 D G YTC+A ++ G+ + LLV+ + P + + + + G K Sbjct: 328 LDDEGEYTCIAKNKVGEVSCTAELLVEEGMRPPQFIVKPSSLQIMEGKMAK 378 Score = 62.5 bits (145), Expect = 7e-08 Identities = 58/210 (27%), Positives = 88/210 (41%), Gaps = 19/210 (9%) Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDG--- 255 I P + D+ G++VT + V G P P+V W + +P R +V G Sbjct: 1 IPPEFKSALRDIEVNEGNTVTLRIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVY 60 Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-----DPPSINLSPNSVNVESGNVA 310 +L + +D G+Y C+A NS G V++S + V +PP + + + G Sbjct: 61 TLVIKEARGSDTGKYLCKAYNSAGEVTSSCNVDVLHVAPKEPPKFERNLKDITIAEGCST 120 Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370 RF TG PEP +FW G ++ P RD H V D I D Sbjct: 121 RFDVQVTGSPEPKVFWYHNGK--LVQP---RD--HVDIVHDDEHSSLILMHCPLDLSGKY 173 Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPII 400 C A N + VR ++ VT + P P++ Sbjct: 174 TCVAENEVENDAVRLEVEVTGE---PKPVV 200 Score = 56.8 bits (131), Expect = 3e-06 Identities = 43/183 (23%), Positives = 70/183 (38%), Gaps = 8/183 (4%) Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 PP + + V GN TG P+P + W +G G+ ++ V + Sbjct: 2 PPEFKSALRDIEVNEGNTVTLRIHVTGSPKPEVDWFKDGKPV---SGLPHRRFEVGCVGE 58 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411 V L I + +D+ +C A N AG + V + PP + T+ Sbjct: 59 -VYTLVIKEARGSDT-GKYLCKAYNSAGEVTSSCNVDVLHVAPKEPPKFERNLKDITIAE 116 Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTCV 468 F +PEP + WY G+ + ++ +D +L+L SG YTCV Sbjct: 117 GCSTRFDVQVTGSPEPKVFWYHNGKLVQPRDHVDIVHDDEHSSLILMHCPLDLSGKYTCV 176 Query: 469 ASS 471 A + Sbjct: 177 AEN 179 Score = 54.4 bits (125), Expect = 2e-05 Identities = 45/178 (25%), Positives = 74/178 (41%), Gaps = 4/178 (2%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I +P + + + A R G P P + W + G + I L Sbjct: 360 PQFIVKPSSLQIMEGKMAKFEARVSGLPGPEVEWLRDGRPIKPGRRFQIEFEKDRSVLTI 419 Query: 72 THGRVHSDAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130 ++ +D G Y C AT+ G + S + AV+ EF + + + +G+ + + Sbjct: 420 IDAKL-NDEGEYTCVATSKAGKDSCSVELLVDEAVVPPEFVRKISNIELTEGEIARFD-V 477 Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAG 187 G+P P V W K+ + G ++ D +LVI+D +D G Y C A N AG Sbjct: 478 RITGTPAPEVTWYKDEVPIEDGGRFEIYSDDDKHSLVIRDCALSDTGSYSCKATNEAG 535 >UniRef50_O15394 Cluster: Neural cell adhesion molecule 2 precursor; n=35; Tetrapoda|Rep: Neural cell adhesion molecule 2 precursor - Homo sapiens (Human) Length = 837 Score = 120 bits (289), Expect = 2e-25 Identities = 148/604 (24%), Positives = 239/604 (39%), Gaps = 56/604 (9%) Query: 6 VTSGEAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64 V+SG+A + L V ++ + C A G P +I WY + T R ++ G Sbjct: 14 VSSGQALLQVTISLSKVELSVGESKFFTCTAIGEPR-SIDWYNPQGEKIISTQRVVVQKG 72 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124 G+ + DAG+Y C+AT++ G + L + + FR ++ QG+ Sbjct: 73 GVRSRLTIYNANIEDAGIYRCQATDAKGQTQEATVVLEI-YQKLTFREVVSPQEFKQGED 131 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR- 183 + C SP P V W + + + D+R+ ++ NL I + ++D G Y+C R Sbjct: 132 AEVVC-RVSSSPAPAVSWLYHNEEVTTISDNRLAMLANNNLQILNINKSDEGIYRCEGRV 190 Query: 184 NAAGTRESAIATLKIHIKPYLITGPE---DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 A G + + +++ P I+ P+ + A+ G +TF CR G P P + W R+ Sbjct: 191 EARGEIDFRDIIVIVNVPP-AISMPQKSFNATAERGEEMTFSCRASGSPEPAISWFRN-- 247 Query: 241 GGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297 G + K + GS L + N+I +D G Y C A N G +L V+ P I Sbjct: 248 -GKLIEENEKYILKGSNTELTVRNIINSDGGPYVCRATNKAGEDEKQAFLQVFVQPHIIQ 306 Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFW--SVEGNRTIIFPGMSRDKYHATAVFDGVTV 355 N E+G V C A G P P + W +V+G T S D G + Sbjct: 307 LKNETTYENGQVT-LVCDAEGEPIPEITWKRAVDG-FTFTEGDKSPDGRIEVKGQHGSSS 364 Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415 L I D K C A + G + ++ D + P I+N + + Sbjct: 365 LHIKDV-KLSGSGRYDCEAASRIGGH----QKSMYLDIEYAPKFISNQTIYYSWEGNPIN 419 Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDS--GTYTCVAS 470 + C P I W + L + N+ T ++L+ SD+ G Y C A+ Sbjct: 420 I-SCDVKSNPPASIHWRRDKLVLPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTAT 478 Query: 471 SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530 + G + ADV P P ++ T+ +S+++ + Sbjct: 479 NHIGTRFQE-------------YILALADV---PSSPYGVKIIELSQTTAKVSFNKPDSH 522 Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590 G I YQV+V +E S W ++ QT V+ +L P TY V Sbjct: 523 GGVPIHHYQVDV--KEVA--------SEIWKIVRSHGVQTMVVLNNLEPNTTYEIRVAAV 572 Query: 591 NSHG 594 N G Sbjct: 573 NGKG 576 >UniRef50_Q90478 Cluster: Neural cell adhesion molecule L1.1; n=9; Cyprinidae|Rep: Neural cell adhesion molecule L1.1 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 1197 Score = 120 bits (289), Expect = 2e-25 Identities = 129/516 (25%), Positives = 210/516 (40%), Gaps = 44/516 (8%) Query: 39 PSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRN 98 PSP+ RW K G +L G T +H G Y C A N GTA S Sbjct: 7 PSPSFRWVKDG-----KQFGEVLSESGTLTPHPTMD-LHFYQGTYRCYAANELGTAVSNL 60 Query: 99 ATLHVAVLREEFRLEPESKQSAQ-GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM 157 L + +++ + +++ + G++ VL C PP+ S P ++W + Q + R+ Sbjct: 61 VHLTTEPVPSLAKVKKQKRRAYEVGESAVLRCNPPKSSVTPKIHW-MDMQFHHIPLNERV 119 Query: 158 HLVDGGNLVIQDARQTDA-GRYQCIARNAAGTRESAIATLKIHIKP-------------Y 203 + GNL + D+ Y C A + + I++ P + Sbjct: 120 TISRDGNLYFANLIANDSRDDYTCNAHYINASIILPKEPMSIYVTPSNSVVKNRRAKLHH 179 Query: 204 LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVI 263 + G ++T QC G P P+V W R P K+ ++ L++DNV+ Sbjct: 180 PAGARSSYLVLRGQTLTLQCIPEGLPTPEVHWDR-IDSALSPNRTKKLYNNRWLQIDNVL 238 Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPT 323 +D+GEY C A NS +V +TV P SP G R C A G P P Sbjct: 239 ESDDGEYVCTARNSENSVKHHYTVTVEAAPYWTRSPEEHLYAPGETVRLDCKADGIPAPN 298 Query: 324 MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383 + WS+ G P D V G +L ++ + +D+ C AVN GS + Sbjct: 299 ITWSING-----VPVSGTDVDPRRRVSSGKLIL--SNVEFSDTA-VYQCEAVNKHGSILI 350 Query: 384 RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-YFEGEALIQNH 442 + V + P I+T + C +P P I W + + N Sbjct: 351 NTHVHVV---ELPAQILTPDERLYQATAGQTVMLDCRTFGSPLPKIHWEILDSIPALSNA 407 Query: 443 RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPI-NP--NIHFFRAAD 499 + + T +G+L + ++ + DS YTC S + +L + I P N+H R +D Sbjct: 408 KISQTTNGSLKISNVSEEDSNRYTCSVSETNKSISADVEVLNRTKIVGPPQNLHVIRGSD 467 Query: 500 VSSLPGPPTKPITHNVTDTSVTLSWSQN-NKIGSSS 534 + L T + HN+ S T+ W+++ +KI +S+ Sbjct: 468 -AILHCKYT--VDHNL--KSPTVQWNKDGHKITAST 498 Score = 111 bits (266), Expect = 1e-22 Identities = 180/806 (22%), Positives = 312/806 (38%), Gaps = 64/806 (7%) Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82 V R Q TL C G P+P + W + + + + + L + SD G Sbjct: 189 VLRGQTLTLQCIPEGLPTPEVHWDRIDSALSPNRTKKLYNNRWL----QIDNVLESDDGE 244 Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW 142 Y C A NS + + + T+ V R PE A G+TV L+C G P PN+ W Sbjct: 245 YVCTARNSENSVK-HHYTVTVEAAPYWTR-SPEEHLYAPGETVRLDC-KADGIPAPNITW 301 Query: 143 KKNGQTLL-FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI- 200 NG + D D R V G L++ + +D YQC A N G S + +H+ Sbjct: 302 SINGVPVSGTDVDPRRR-VSSGKLILSNVEFSDTAVYQCEAVNKHG---SILINTHVHVV 357 Query: 201 -KPYLITGPEDVV--AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257 P I P++ + A G +V CR G PLP + W + ++ +GSL Sbjct: 358 ELPAQILTPDERLYQATAGQTVMLDCRTFGSPLPKIHWEILDSIPALSNAKISQTTNGSL 417 Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317 ++ NV D Y+C + ++SA + V + I P +++V G+ A C T Sbjct: 418 KISNVSEEDSNRYTCSVSETNKSISAD--VEVLNRTKIVGPPQNLHVIRGSDAILHCKYT 475 Query: 318 ---GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374 PT+ W+ +G++ I S DKYH + + VL + D C Sbjct: 476 VDHNLKSPTVQWNKDGHK--ITASTSNDKYH--EIEGSLKVLDVQMED----MGIYSCEV 527 Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFE 434 S G +TV D P + + +++ I M + T E +I E Sbjct: 528 STTLDSDTASGYITVQDKPDPPQSLKLSEKMERSVTISWMPSVENNSPVT-EYVIEMN-E 585 Query: 435 GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHF 494 GE + + + V +D+ DS C S H + ++ +P ++ + Sbjct: 586 GETPDEGQWQKYRS----VSQDI---DSWRSICSYSKYHFQIRAVNSIGTSAPTESSLSY 638 Query: 495 FRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETL-SGNNT 553 + + P +T + S+ +SW + ++ + G+Q +VF R SG + Sbjct: 639 --STPAAKPDTNPENVMTLSTDPKSMIISWQEMDRRQFNG-PGFQYKVFWRRAADSGAHW 695 Query: 554 PRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNS 613 +S V +V + +++ V+ N G + P P++ G+D Sbjct: 696 TESS---------VSNPPLMVNNTGTFVSFEIKVQAVNDLG-AAPEPLTVIGYSGEDFP- 744 Query: 614 LWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDN 673 E + TE + T +V P + L ++I + ++G + P Sbjct: 745 -LEAPSALSVTELQK---TSVMVRWSPVRPESVRGHLLGYKI--YLRMKG-SQWETPGRA 797 Query: 674 ITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDG 733 ++ I D + ++ L+ Y+ Y + F K EG P + T + P G Sbjct: 798 VSSSGNPTVIEVPADAAEKIVSDLQFYSDYTLTITAFNSKGEG-PHSEESFSTPEGAP-G 855 Query: 734 PPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT 793 P + + + + + L+W P NG I GY + + + + + + T Sbjct: 856 PVLFLPFDSPSESEITLRWEAP--HKPNGEIRGYLLQYQEVVIGSESPQHVESIDLPAVT 913 Query: 794 SLIMTNLTSGVSYSVQIAAETIIGLG 819 + NL Y+ ++A G G Sbjct: 914 EFTLKNLNPESRYTFHLSARNDAGDG 939 Score = 108 bits (260), Expect = 8e-22 Identities = 84/295 (28%), Positives = 136/295 (46%), Gaps = 17/295 (5%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAG 64 VT APY P + A + L+C+A G P+P I W GV V +D + Sbjct: 262 VTVEAAPYWTRSPEEHLYAPGETVRLDCKADGIPAPNITWSINGVPVSGTDVDPRRRVSS 321 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQG 122 G L SD VY CEA N +G+ N +HV L + L P+ + Q+ G Sbjct: 322 GKLILSNVE---FSDTAVYQCEAVNKHGSILI-NTHVHVVELPAQI-LTPDERLYQATAG 376 Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182 TV+L+C GSP P ++W+ ++++ G+L I + + D+ RY C Sbjct: 377 QTVMLDCRT-FGSPLPKIHWEILDSIPALS-NAKISQTTNGSLKISNVSEEDSNRYTC-- 432 Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD---PLPDVLWRRSA 239 + + T +S A +++ + ++ P+++ GS C+ D P V W + Sbjct: 433 -SVSETNKSISADVEVLNRTKIVGPPQNLHVIRGSDAILHCKYTVDHNLKSPTVQWNKDG 491 Query: 240 GGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293 K + +GSL++ +V + D G YSCE ++ + +ASGY+TV D P Sbjct: 492 HKITASTSNDKYHEIEGSLKVLDVQMEDMGIYSCEVSTTLDSDTASGYITVQDKP 546 >UniRef50_UPI0000ECD748 Cluster: UPI0000ECD748 related cluster; n=1; Gallus gallus|Rep: UPI0000ECD748 UniRef100 entry - Gallus gallus Length = 2179 Score = 120 bits (288), Expect = 3e-25 Identities = 106/352 (30%), Positives = 151/352 (42%), Gaps = 25/352 (7%) Query: 2 SDDYVTSGEAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYK--GGVLVVSDTH- 57 S ++ T GE P II + +++ A + C A G P P I W K G L+ + T Sbjct: 1828 SSNFRTPGERPKIITKGSQSISILAETDALIPCDAVGEPKPFITWTKVSTGALMTAHTRL 1887 Query: 58 -RSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPES 116 R + G F +R + D G Y C A N +G + A VA + + Sbjct: 1888 QRFEVLKNGTFLIRNAQLQ---DRGQYLCTAQNLHGIDKMIFALTVVAHQPKILLSRYQD 1944 Query: 117 KQSAQGDTVVLECLPPRGSPEPNVYW----KKNGQTLLFDGDSRMHLVDGGNLVIQDARQ 172 GDT+ LEC G+P P++ W K QT+ +SR+ L + L I+ A Sbjct: 1945 VTVYFGDTIALEC-QASGTPSPHISWIFPDTKILQTVTTT-ESRIMLHENRTLSIKQATF 2002 Query: 173 TDAGRYQCIARNAAGTRESAIATLKIHIKPYLI--TGPEDVVAQTGSSVTFQCRVGGDPL 230 +D G Y+C+A NAAG +S L I P +I E++ GSS+ C P Sbjct: 2003 SDRGVYKCVASNAAGA-DSIAVRLHIAALPPIIQQDKQENISLPLGSSINIHCTAKAAPS 2061 Query: 231 PDVLWRRSAGGGNMPL----GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY 286 P + W G P G + V +G+L + NV D G Y C A N VGA Sbjct: 2062 PSIRWVLFDGTQIRPSQFVNGNLFVFPNGTLYIRNVSPKDSGIYECIAANMVGAARRIIQ 2121 Query: 287 LTVYDPPS----INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334 L V S SP +V G++ C+A+G P P + W + R I Sbjct: 2122 LHVKKQASNAKITGSSPQRTDVTYGSILHLDCSASGDPWPRILWRLPSKRMI 2173 Score = 94.7 bits (225), Expect = 1e-17 Identities = 82/288 (28%), Positives = 123/288 (42%), Gaps = 24/288 (8%) Query: 201 KPYLIT-GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP----LGRVKVLDDG 255 +P +IT G + + + C G+P P + W + + G M L R +VL +G Sbjct: 1837 RPKIITKGSQSISILAETDALIPCDAVGEPKPFITWTKVSTGALMTAHTRLQRFEVLKNG 1896 Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-DPPSINLSP-NSVNVESGNVARFT 313 + + N L D G+Y C A+N G LTV P I LS V V G+ Sbjct: 1897 TFLIRNAQLQDRGQYLCTAQNLHGIDKMIFALTVVAHQPKILLSRYQDVTVYFGDTIALE 1956 Query: 314 CTATGRPEPTMFWSVEGNRTI--IFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371 C A+G P P + W + + + SR H L+I +D R Sbjct: 1957 CQASGTPSPHISWIFPDTKILQTVTTTESRIMLHENRT------LSIKQATFSD-RGVYK 2009 Query: 372 CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431 C A N AG+ + +L + + PP I + N +LP+ S CTA P P I W Sbjct: 2010 CVASNAAGADSIAVRLHIAA---LPPIIQQDKQENISLPLGSSINIHCTAKAAPSPSIRW 2066 Query: 432 -YFEGEAL----IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 F+G + N V +GTL ++++ DSG Y C+A++ G Sbjct: 2067 VLFDGTQIRPSQFVNGNLFVFPNGTLYIRNVSPKDSGIYECIAANMVG 2114 Score = 51.2 bits (117), Expect = 2e-04 Identities = 35/110 (31%), Positives = 52/110 (47%), Gaps = 6/110 (5%) Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-YFEGEALIQNHRR----NVTNDGT 451 P IIT G + ++ ++ A+ PC A+ P+P I W AL+ H R V +GT Sbjct: 1838 PKIITKGSQSISILAETDALIPCDAVGEPKPFITWTKVSTGALMTAHTRLQRFEVLKNGT 1897 Query: 452 LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVS 501 ++++ D G Y C A + HG AL V + P I R DV+ Sbjct: 1898 FLIRNAQLQDRGQYLCTAQNLHGIDKMIFALTVVAH-QPKILLSRYQDVT 1946 Score = 50.0 bits (114), Expect = 4e-04 Identities = 47/188 (25%), Positives = 79/188 (42%), Gaps = 17/188 (9%) Query: 105 VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL---FDG-DSRMHLV 160 ++ E+ + +++ +G L C + S P + W T L F+ DSR ++ Sbjct: 470 IMIEQNQSTRKAQSVVEGSECQLNC-NVKASERPFIQWLFPDGTKLQAPFNQKDSRFSIL 528 Query: 161 DGGNLVIQDARQTDAGRYQCIARNAAGTRESA-IATLKIHIKPYLI-TGPEDVV---AQT 215 G LVI+ TDAG Y CIA+ R+ + ++ ++P I D+V Sbjct: 529 TSGQLVIKPVSYTDAGLYHCIAQ----VRDDIDVMAYRLLVQPPAIQVADSDIVRVEKNV 584 Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK---VLDDGSLRLDNVILADEGEYSC 272 G + C P + W + L VLD+G+L + ++D G Y C Sbjct: 585 GDPIVLPCSAIASPEAQLSWILPSSQVLNVLSNFSKGYVLDNGTLLIPKSHISDSGHYRC 644 Query: 273 EAENSVGA 280 A N +G+ Sbjct: 645 VAVNQLGS 652 Score = 47.6 bits (108), Expect = 0.002 Identities = 46/177 (25%), Positives = 77/177 (43%), Gaps = 17/177 (9%) Query: 22 TVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVS-----DTHRSILPAGGLFFLRATHGR 75 +V LNC S P I+W + G + + D+ SIL +G L + Sbjct: 483 SVVEGSECQLNCNVKASERPFIQWLFPDGTKLQAPFNQKDSRFSILTSGQLVIKPVS--- 539 Query: 76 VHSDAGVYWC--EATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133 ++DAG+Y C + + R A+ + + K GD +VL C Sbjct: 540 -YTDAGLYHCIAQVRDDIDVMAYRLLVQPPAIQVADSDIVRVEKN--VGDPIVLPC-SAI 595 Query: 134 GSPEPNVYW-KKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188 SPE + W + Q L + S+ +++D G L+I + +D+G Y+C+A N G+ Sbjct: 596 ASPEAQLSWILPSSQVLNVLSNFSKGYVLDNGTLLIPKSHISDSGHYRCVAVNQLGS 652 Score = 40.7 bits (91), Expect = 0.24 Identities = 22/63 (34%), Positives = 35/63 (55%), Gaps = 4/63 (6%) Query: 416 VFPCTAICTPEPIIAWYFEGEALIQ---NHRRN-VTNDGTLVLKDLDKSDSGTYTCVASS 471 V PC+AI +PE ++W ++ N + V ++GTL++ SDSG Y CVA + Sbjct: 589 VLPCSAIASPEAQLSWILPSSQVLNVLSNFSKGYVLDNGTLLIPKSHISDSGHYRCVAVN 648 Query: 472 RHG 474 + G Sbjct: 649 QLG 651 Score = 37.1 bits (82), Expect = 2.9 Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 6/75 (8%) Query: 419 CTAICTPEPIIAWYFEGEALIQ------NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472 C + P I W F +Q + R ++ G LV+K + +D+G Y C+A R Sbjct: 494 CNVKASERPFIQWLFPDGTKLQAPFNQKDSRFSILTSGQLVIKPVSYTDAGLYHCIAQVR 553 Query: 473 HGKYVWSGALLVDSP 487 V + LLV P Sbjct: 554 DDIDVMAYRLLVQPP 568 >UniRef50_A7S4D5 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 637 Score = 118 bits (285), Expect = 7e-25 Identities = 66/193 (34%), Positives = 97/193 (50%), Gaps = 8/193 (4%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 + P +E+P V R +NC +P W K G + D +L +G L + Sbjct: 23 QPPRFVEEPSAVIALRKSTVQINCSTIATPVARTIWLKDGARIKPDDRHVVLTSGALR-I 81 Query: 70 RATHGR---VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126 ++ GR +D GVY C A+N GT SR TLH+AVL +F +P+S + +G T Sbjct: 82 QSVQGRRKGFGNDEGVYQCLASNRAGTVASRKVTLHIAVLSRKFEEQPQSINAWEGTTAR 141 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNA 185 C + P P++ W+ NGQ ++ S+ H+V G L I + +Q D G YQC+A N Sbjct: 142 FSCKVKKAYPAPSISWEHNGQVIV---PSKRHVVLPNGALQIHNVQQVDQGTYQCVASNI 198 Query: 186 AGTRESAIATLKI 198 A R S ATL + Sbjct: 199 ARIRRSNTATLTV 211 Score = 71.3 bits (167), Expect = 1e-10 Identities = 46/152 (30%), Positives = 73/152 (48%), Gaps = 9/152 (5%) Query: 666 IYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQ 725 I ++P D + E + ++ + D + I SL +TKY F++ PF+ K +G S Q Sbjct: 494 INYQPADKSSKELQ---VVLAKDFTSEVIRSLSGFTKYTFYVTPFFTKGQGLNSEVITVQ 550 Query: 726 TLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAI 785 TL P P NI + L ++ + W PP + +NGI+T Y + + NKS+ Sbjct: 551 TLPGKPSTSPGNIVLNSLTPDSIDVSWDPPPKRYRNGILTSYIIKYH------NKSISET 604 Query: 786 NTTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817 ++ L SG Y VQ+AA T +G Sbjct: 605 ILLPSSMQKKTISGLASGEVYMVQVAAATKMG 636 Score = 69.3 bits (162), Expect = 6e-10 Identities = 53/171 (30%), Positives = 79/171 (46%), Gaps = 10/171 (5%) Query: 113 EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV--IQDA 170 EP + + + TV + C +P W K+G + D D + L G + +Q Sbjct: 30 EPSAVIALRKSTVQINC-STIATPVARTIWLKDGARIKPD-DRHVVLTSGALRIQSVQGR 87 Query: 171 RQ---TDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG-PEDVVAQTGSSVTFQCRVG 226 R+ D G YQC+A N AGT S TL I + P+ + A G++ F C+V Sbjct: 88 RKGFGNDEGVYQCLASNRAGTVASRKVTLHIAVLSRKFEEQPQSINAWEGTTARFSCKVK 147 Query: 227 -GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAEN 276 P P + W + G +P R VL +G+L++ NV D+G Y C A N Sbjct: 148 KAYPAPSISWEHN-GQVIVPSKRHVVLPNGALQIHNVQQVDQGTYQCVASN 197 Score = 60.5 bits (140), Expect = 3e-07 Identities = 83/344 (24%), Positives = 131/344 (38%), Gaps = 39/344 (11%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDN 261 P + P V+A S+V C P+ +W + G P R VL G+LR+ + Sbjct: 25 PRFVEEPSAVIALRKSTVQINCSTIATPVARTIWLKD-GARIKPDDRHVVLTSGALRIQS 83 Query: 262 V------ILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLSPNSVNVESGNVARF 312 V DEG Y C A N G V AS +T++ P S+N G ARF Sbjct: 84 VQGRRKGFGNDEGVYQCLASNRAGTV-ASRKVTLHIAVLSRKFEEQPQSINAWEGTTARF 142 Query: 313 TC-TATGRPEPTMFWS------VEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365 +C P P++ W V R ++ P + ++ V G ++ + Sbjct: 143 SCKVKKAYPAPSISWEHNGQVIVPSKRHVVLPNGALQIHNVQQVDQGTYQCVASNIARIR 202 Query: 366 SRN--TIVCSAVNYAG----SSFV-RGKL-------TVTSDDDRPPPIITNGPSNQTLPI 411 N T+ V + G ++F+ + K+ + P T PSN ++ Sbjct: 203 RSNTATLTVQQVLWQGRIAPTAFLPKVKVIYLGTYCSFIKTKSSKQPNFTTIPSNTSVIS 262 Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG--TLVLKDLDKSDSGTYTCVA 469 AV C A P P + W G A + + ++ G L ++ D G Y C+ Sbjct: 263 GEEAVLECIATGVPVPTVQWKKVGGA-DRAYDYSLAKPGGCNLRIRSASPKDGGEYMCIV 321 Query: 470 SSRHGKYVWSGALLVDSPINPNIHFFRAAD---VSSLPGPPTKP 510 S+ S L V + ++ FF + V LP +KP Sbjct: 322 SASGRSMTHSTFLSVQGRL-VDLDFFVVCNFRRVFFLPSVYSKP 364 Score = 59.7 bits (138), Expect = 5e-07 Identities = 55/206 (26%), Positives = 86/206 (41%), Gaps = 16/206 (7%) Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR------TIIFPGMSRDKYHA 346 P+ P++ +V SG A C ATG P PT+ W G ++ PG + + Sbjct: 249 PNFTTIPSNTSVISGEEAVLECIATGVPVPTVQWKKVGGADRAYDYSLAKPGGCNLRIRS 308 Query: 347 TAVFDGVTVLTI-NDTDKNDSRNTIVCSAVNYAGSSFV-----RGKLTVTSDDDRPPPII 400 + DG + I + + ++ + +T + F R + S +PP I Sbjct: 309 ASPKDGGEYMCIVSASGRSMTHSTFLSVQGRLVDLDFFVVCNFRRVFFLPSVYSKPPHFI 368 Query: 401 TNGPS--NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLD 458 N P L I + C+A P P I W G+ L+ N R++ N+ LV++ L Sbjct: 369 -NTPKLPKGLLDIGATLTLQCSATGVPPPRITWLKNGKELVGNQRQSGINN-DLVIQSLS 426 Query: 459 KSDSGTYTCVASSRHGKYVWSGALLV 484 DSG Y C A + G S +LV Sbjct: 427 TKDSGVYQCFAENDIGSVQTSTRVLV 452 Score = 52.0 bits (119), Expect = 1e-04 Identities = 56/218 (25%), Positives = 87/218 (39%), Gaps = 34/218 (15%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK-NGQTLLFDGDSRMHLVDGGNLVIQ 168 F P + G+ VLEC+ G P P V WKK G +D + G NL I+ Sbjct: 251 FTTIPSNTSVISGEEAVLECIAT-GVPVPTVQWKKVGGADRAYDYS--LAKPGGCNLRIR 307 Query: 169 DARQTDAGRYQCI--ARNAAGTRESAIATL---------------------KIHIKP-YL 204 A D G Y CI A + T + ++ ++ KP + Sbjct: 308 SASPKDGGEYMCIVSASGRSMTHSTFLSVQGRLVDLDFFVVCNFRRVFFLPSVYSKPPHF 367 Query: 205 ITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDN 261 I P+ + G+++T QC G P P + W ++ G +G + + L + + Sbjct: 368 INTPKLPKGLLDIGATLTLQCSATGVPPPRITWLKN---GKELVGNQRQSGINNDLVIQS 424 Query: 262 VILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299 + D G Y C AEN +G+V S + V +N P Sbjct: 425 LSTKDSGVYQCFAENDIGSVQTSTRVLVRRSGKLNTYP 462 Score = 47.2 bits (107), Expect = 0.003 Identities = 46/199 (23%), Positives = 72/199 (36%), Gaps = 18/199 (9%) Query: 279 GAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPG 338 G + G + PP P++V + + C+ P W +G R Sbjct: 11 GNFAVLGSSNLLQPPRFVEEPSAVIALRKSTVQINCSTIATPVARTIWLKDGAR------ 64 Query: 339 MSRDKYHATAVFDGVTVLTINDTDKN--DSRNTIVCSAVNYAG---SSFVRGKLTVTSDD 393 + D H + + ++ K + C A N AG S V + V S Sbjct: 65 IKPDDRHVVLTSGALRIQSVQGRRKGFGNDEGVYQCLASNRAGTVASRKVTLHIAVLSRK 124 Query: 394 DRPPPIITNGPSNQTLPIKSMAVFPCTAI-CTPEPIIAWYFEGEALIQNHRRNVTNDGTL 452 P N T A F C P P I+W G+ ++ + R V +G L Sbjct: 125 FEEQPQSINAWEGTT------ARFSCKVKKAYPAPSISWEHNGQVIVPSKRHVVLPNGAL 178 Query: 453 VLKDLDKSDSGTYTCVASS 471 + ++ + D GTY CVAS+ Sbjct: 179 QIHNVQQVDQGTYQCVASN 197 Score = 46.8 bits (106), Expect = 0.004 Identities = 30/100 (30%), Positives = 43/100 (43%), Gaps = 5/100 (5%) Query: 16 EQPLDVTVARHQPATLNCRAGGS-PSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74 EQP + A +C+ + P+P+I W G ++V +LP G L H Sbjct: 127 EQPQSINAWEGTTARFSCKVKKAYPAPSISWEHNGQVIVPSKRHVVLPNGAL----QIHN 182 Query: 75 RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP 114 D G Y C A+N RS ATL V + + R+ P Sbjct: 183 VQQVDQGTYQCVASNIARIRRSNTATLTVQQVLWQGRIAP 222 Score = 39.1 bits (87), Expect = 0.72 Identities = 36/123 (29%), Positives = 51/123 (41%), Gaps = 15/123 (12%) Query: 30 TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89 TL C A G P P I W K G +V + +S G+ D+GVY C A N Sbjct: 385 TLQCSATGVPPPRITWLKNGKELVGNQRQS-----GINNDLVIQSLSTKDSGVYQCFAEN 439 Query: 90 SYGTARSRNATLHVAVLREEFRLEPESKQSAQG-----DTVVLECLPPRGSPEPNVYWKK 144 G+ ++ L +R +L + G + V + LPPRG PE + + Sbjct: 440 DIGSVQTSTRVL----VRRSGKLNTYPPLNVTGVGISSEEVNISWLPPRG-PEQVLAYSI 494 Query: 145 NGQ 147 N Q Sbjct: 495 NYQ 497 Score = 38.7 bits (86), Expect = 0.96 Identities = 30/104 (28%), Positives = 46/104 (44%), Gaps = 3/104 (2%) Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 GT S I T K +P T P + +G +C G P+P V W++ GG + Sbjct: 235 GTYCSFIKT-KSSKQPNFTTIPSNTSVISGEEAVLECIATGVPVPTVQWKK-VGGADRAY 292 Query: 247 GRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 G +LR+ + D GEY C S +++ S +L+V Sbjct: 293 DYSLAKPGGCNLRIRSASPKDGGEYMCIVSASGRSMTHSTFLSV 336 Score = 36.7 bits (81), Expect = 3.9 Identities = 24/84 (28%), Positives = 34/84 (40%), Gaps = 6/84 (7%) Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKD 456 PP PS KS C+ I TP W +G + + R V G L ++ Sbjct: 24 PPRFVEEPSAVIALRKSTVQINCSTIATPVARTIWLKDGARIKPDDRHVVLTSGALRIQS 83 Query: 457 LDK------SDSGTYTCVASSRHG 474 + +D G Y C+AS+R G Sbjct: 84 VQGRRKGFGNDEGVYQCLASNRAG 107 >UniRef50_UPI00015B5045 Cluster: PREDICTED: similar to receptor tyrosine phosphatase type r2a; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to receptor tyrosine phosphatase type r2a - Nasonia vitripennis Length = 2046 Score = 118 bits (284), Expect = 1e-24 Identities = 99/359 (27%), Positives = 157/359 (43%), Gaps = 30/359 (8%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRS---ILPAGGLFF 68 P I++P V A+ C A GSP P I W K ++S + + P Sbjct: 40 PRFIQKPQSQMVKNGGIASFFCSASGSPPPQIFWRKNNKKIMSTNQSNRFMVYPYENGTL 99 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATL---HVAVLREEFRL---EPESKQSAQG 122 LR R + DA Y C A N G A S A+L V L + F + P +K +G Sbjct: 100 LRIEPVRSNRDAIAYECLAENGVGDAVSATASLTIYEVDKLPKGFPMITQAPTTKVVEKG 159 Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182 L C GSP P + W +N Q + + R +++ G L I D+ D G+Y+C+A Sbjct: 160 HNAQLSC-SAMGSPMPIISWMRN-QLPIDTSNPRYVVLESGALQITDSDPDDQGKYECVA 217 Query: 183 RNAAGTRESAIATLKIHIK---PYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRS 238 N+ GT S L + I+ P+ P+ VV T G S C G P+P V WR+ Sbjct: 218 TNSVGTEYSKSTQLYVKIRRVLPHFSRQPDPVVEVTLGESTNLTCVAYGSPMPYVKWRKE 277 Query: 239 AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298 P ++ + L L NV + Y+C A++ +G ++ + Y+ V S+ L+ Sbjct: 278 PATDLTPDNQMPPIGKNVLHLKNV--HESANYTCIAQSDLGVINTTTYVKV---RSLPLA 332 Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 P +V V+ T T+ + WS +G ++ + + HA + ++ +T Sbjct: 333 PENV-----QVSEITATSV-----KLTWSYKGPESLAYYVIQHKPKHAHQAYAEISGIT 381 Score = 82.2 bits (194), Expect = 8e-14 Identities = 57/187 (30%), Positives = 85/187 (45%), Gaps = 7/187 (3%) Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 PP P S V++G +A F C+A+G P P +FW + N+ I+ S +++ + Sbjct: 39 PPRFIQKPQSQMVKNGGIASFFCSASGSPPPQIFWR-KNNKKIMSTNQS-NRFMVYPYEN 96 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSF-VRGKLTVTSDDDRPP--PIITNGPSNQT 408 G T+L I N C A N G + LT+ D P P+IT P+ + Sbjct: 97 G-TLLRIEPVRSNRDAIAYECLAENGVGDAVSATASLTIYEVDKLPKGFPMITQAPTTKV 155 Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467 + A C+A+ +P PII+W + N R V G L + D D D G Y C Sbjct: 156 VEKGHNAQLSCSAMGSPMPIISWMRNQLPIDTSNPRYVVLESGALQITDSDPDDQGKYEC 215 Query: 468 VASSRHG 474 VA++ G Sbjct: 216 VATNSVG 222 Score = 68.5 bits (160), Expect = 1e-09 Identities = 57/207 (27%), Positives = 90/207 (43%), Gaps = 8/207 (3%) Query: 619 GVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEY 678 GV N+T Y E ++ + I + ++KL W L I +P Sbjct: 316 GVINTTTYVKVRSLPLAPENVQVSEITATSVKLTWSYKGPESLAYYVIQHKPKHAHQAYA 375 Query: 679 EMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINI 738 E+ I + + SL YT+YEFF+I G PS+ V T + P P + Sbjct: 376 EISGIT----TMYYMVRSLSPYTEYEFFVIAVNDIGRGPPSSPVVVTTGETKPGSAPRRV 431 Query: 739 EMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMT 798 ++ L++TT ++W PE NG +TGY V D S T + + I + Sbjct: 432 QVRPLSSTTALIQWDEPE--TPNGQVTGYKVYYT-TDSGQPMSNWQFQTVDNNQLTTI-S 487 Query: 799 NLTSGVSYSVQIAAETIIGLGPFSQKV 825 +LT+ Y++++ A T +G GP S V Sbjct: 488 DLTAHAIYTIRVQALTSVGPGPLSSPV 514 Score = 66.9 bits (156), Expect = 3e-09 Identities = 55/213 (25%), Positives = 100/213 (46%), Gaps = 13/213 (6%) Query: 639 IEATPIDSKTIKLMWEILNFYYLEGLFIYFRP--LDNITIEYEMKTILHSNDVSGFEITS 696 + P +I + WE G +Y++ ++N + E +I+ N F + Sbjct: 625 VTGLPTSPTSILVKWEPPPVERSNGRIVYYKLHYVENGRSDSE-SSIVTLNGTE-FVLDE 682 Query: 697 LRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPE 756 L+K+T+Y +++ +G PS +T +DVP G P N++ +N T ++++W PP+ Sbjct: 683 LKKWTEYRIWVVAGTSVGDGPPSYPITVRTHEDVP-GDPQNVKATPINATAIYVEWEPPK 741 Query: 757 LQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTS---GVSYSVQIAAE 813 + +NGII GY+V V + + ++ ++ N++ Y VQ+AA Sbjct: 742 SKERNGIIRGYHVHVQEVSEETKNQLNDPIRSISLEEDVLHVNISGLQPDTRYDVQVAAL 801 Query: 814 TIIGLG----PFSQKVYFNIDSR-SVGLDLLSR 841 T G G P S K + SR S+ + +SR Sbjct: 802 TRKGDGARSIPVSVKTPGGVPSRPSLIIKTISR 834 Score = 58.4 bits (135), Expect = 1e-06 Identities = 41/134 (30%), Positives = 60/134 (44%), Gaps = 12/134 (8%) Query: 728 DDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINT 787 + P GPP N+ TV + W PP+ + +NG I YN V + + S V N Sbjct: 917 EGAPTGPPTNLSFHFQTPDTVCVTWDPPQQKFRNGKIVSYN--VQFHKKSDHTSEVTRNI 974 Query: 788 TVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGE 847 T T + TNL Y + A T G GP+S+K+ D + +G R PM+ + Sbjct: 975 T---KTRAVFTNLDENTEYVFHVKAYTSRGGGPYSEKITILTD-KDIG-----RAPMSVK 1025 Query: 848 VSIVAGDFVMETWF 861 +I D E W+ Sbjct: 1026 -AIATSDSSAEVWW 1038 Score = 51.2 bits (117), Expect = 2e-04 Identities = 34/134 (25%), Positives = 62/134 (46%), Gaps = 4/134 (2%) Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751 + +T+L T Y +L ++ EG + +T VP PP N+ + T++ +K Sbjct: 579 YTLTNLYPNTLYYVWLAARSQRGEGATTIPLPVRTEQYVPGAPPRNVTGLPTSPTSILVK 638 Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811 W PP ++ NG I Y +++++ + S +I T T ++ L Y + + Sbjct: 639 WEPPPVERSNGRIVYYK--LHYVENGRSDSESSIVTL--NGTEFVLDELKKWTEYRIWVV 694 Query: 812 AETIIGLGPFSQKV 825 A T +G GP S + Sbjct: 695 AGTSVGDGPPSYPI 708 Score = 35.5 bits (78), Expect = 8.9 Identities = 43/205 (20%), Positives = 83/205 (40%), Gaps = 13/205 (6%) Query: 639 IEATPIDSKTIKLMWEILNFY----YLEGLFIYFRPLDNIT---IEYEMKTILHSNDVSG 691 ++ATPI++ I + WE + G ++ + + T + +++I DV Sbjct: 723 VKATPINATAIYVEWEPPKSKERNGIIRGYHVHVQEVSEETKNQLNDPIRSISLEEDVLH 782 Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFIL-NTTTVHL 750 I+ L+ T+Y+ + +K +G S +T VP P + I+ + + L Sbjct: 783 VNISGLQPDTRYDVQVAALTRKGDGARSIPVSVKTPGGVPSRPSLIIKTISREDPIEMQL 842 Query: 751 KWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQI 810 W+ P G I GY + ++ K + +VH I GV Y ++ Sbjct: 843 DWTRPTQTY--GQILGYRIRYGIINQTL-KEVFLEGDSVHSYR--IKDLEERGVDYEFRV 897 Query: 811 AAETIIGLGPFSQKVYFNIDSRSVG 835 A + +G G + +F+ + G Sbjct: 898 AGKNEVGFGQEQVRNWFSQEGAPTG 922 >UniRef50_Q4SPP8 Cluster: Chromosome 16 SCAF14537, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 16 SCAF14537, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 590 Score = 118 bits (284), Expect = 1e-24 Identities = 91/319 (28%), Positives = 145/319 (45%), Gaps = 20/319 (6%) Query: 24 ARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTH---RSILPAGGLFFLRATHGRVHSDA 80 A+ ++C+A G+P+P+I W + ++ + R + G +R +D Sbjct: 219 AKFSRKLIDCKAEGNPTPSITWIMPDNIFLTVPYFGSRINVHRNGTLEIRNVR---PTDT 275 Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ--SAQGDTVVLECLPPRGSPEP 138 + C A N G A +LR P +++ S G T++L C G P P Sbjct: 276 AEFICLARNDGGEAVMVVQLEVTGLLRRPIFKNPFNERIVSQIGKTIILNC-SADGHPSP 334 Query: 139 NVYWK-KNGQTLLFDGD--SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195 + W NG + S H+ G+LVI+ ++ DAG Y+C ARN G E I Sbjct: 335 QIVWTFPNGTRFSNKAEHGSHFHIRKDGSLVIRPGKE-DAGNYRCGARNYMGYIEKLI-I 392 Query: 196 LKIHIKPYLITGPEDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSAG---GGNMPLGRVKV 251 L++ KPY++T P V+ + +G + C G P P + W G LGR ++ Sbjct: 393 LEVGQKPYIMTRPRGVIRSVSGEPLFLHCLSDGSPTPKIYWTIPGGHTLSHPQILGRHQL 452 Query: 252 LDDGSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSP-NSVNVESGNV 309 L++G+L +++ L D G Y C A N G AV + V PP I + P +V G Sbjct: 453 LENGTLVVEHTTLHDRGNYICRARNDAGEAVIIVPVVIVAYPPRITIGPLPNVKATRGTP 512 Query: 310 ARFTCTATGRPEPTMFWSV 328 + +C A G P+P + W + Sbjct: 513 LQLSCAAIGIPKPEITWEL 531 Score = 113 bits (273), Expect = 2e-23 Identities = 123/487 (25%), Positives = 199/487 (40%), Gaps = 49/487 (10%) Query: 18 PLDVTVARHQPA---TLNCRAGGSPSPAIRWY-KGGVLVVSDTHRSILPAGGLFFLRATH 73 P T AR +P +C A G P P I W ++ + R ++ G +R Sbjct: 112 PPSQTYARVKPGGSIRFDCEAVGEPKPKIFWMLPTNDVIAASNERYLVHVNGSLDIRDI- 170 Query: 74 GRVHSDAGVYWCEATNSYGTARS---RNATLHVAVLREEFRLEPESKQ-SAQGDTVVLEC 129 RV SD G Y C A N G R + + V+ + K +A+ +++C Sbjct: 171 -RV-SDTGEYVCMARNPAGENRKVYKLDIDGNPPVINGHRQNRTVIKDVAAKFSRKLIDC 228 Query: 130 LPPRGSPEPNVYWKKNGQTLL---FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186 G+P P++ W L + G SR+++ G L I++ R TD + C+ARN Sbjct: 229 -KAEGNPTPSITWIMPDNIFLTVPYFG-SRINVHRNGTLEIRNVRPTDTAEFICLARNDG 286 Query: 187 GTRESAIATLKIHIKPYL----ITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 G A+ +++ + L P E +V+Q G ++ C G P P ++W G Sbjct: 287 G---EAVMVVQLEVTGLLRRPIFKNPFNERIVSQIGKTIILNCSADGHPSPQIVWTFPNG 343 Query: 241 ---GGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296 G + DGSL + D G Y C A N +G + L V P I Sbjct: 344 TRFSNKAEHGSHFHIRKDGSLVI-RPGKEDAGNYRCGARNYMGYIEKLIILEVGQKPYIM 402 Query: 297 LSPNSV-NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355 P V SG C + G P P ++W++ G T+ P + + + T Sbjct: 403 TRPRGVIRSVSGEPLFLHCLSDGSPTPKIYWTIPGGHTLSHPQI----LGRHQLLENGT- 457 Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415 L + T +D R +C A N AG + + + + + PP IT GP + Sbjct: 458 LVVEHTTLHD-RGNYICRARNDAGEAVIIVPVVIVAY----PPRITIGPLPNVKATRGTP 512 Query: 416 V-FPCTAICTPEPIIAWYFEGEALIQNHRRN-------VTNDGTLVLKDLDKSDSGTYTC 467 + C AI P+P I W +++ + ++ + GTL+++ SD+G Y C Sbjct: 513 LQLSCAAIGIPKPEITWELPDRSVLSSTQQGRPTGGELLHPQGTLIIQRPSVSDTGRYKC 572 Query: 468 VASSRHG 474 +A + G Sbjct: 573 LAKNYLG 579 Score = 113 bits (272), Expect = 3e-23 Identities = 138/560 (24%), Positives = 221/560 (39%), Gaps = 59/560 (10%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF--FLRATHGRVH------SDAGV 82 ++C+A G+P P I W +VS ++ + +GG + +G ++ S+ G Sbjct: 24 VDCKASGAPKPEISWGLPDGTMVSSAFQADVSSGGQAQRYTLFDNGTLYLNQVSISEEGD 83 Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GDTVVLECLPPRGSPEPN 139 Y C A N G T+H++V+ + P S+ A+ G ++ +C G P+P Sbjct: 84 YICYAENHLG---KDEMTVHISVMTVTPVIHPPSQTYARVKPGGSIRFDC-EAVGEPKPK 139 Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199 ++W ++ + R + G+L I+D R +D G Y C+ARN AG + L I Sbjct: 140 IFWMLPTNDVIAASNERYLVHVNGSLDIRDIRVSDTGEYVCMARNPAGENRK-VYKLDID 198 Query: 200 IKPYLITGP-------EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG-GGNMPL--GRV 249 P +I G +DV A+ S C+ G+P P + W +P R+ Sbjct: 199 GNPPVINGHRQNRTVIKDVAAKF-SRKLIDCKAEGNPTPSITWIMPDNIFLTVPYFGSRI 257 Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD----PPSINLSPNSVNVE 305 V +G+L + NV D E+ C A N G L V P N + + Sbjct: 258 NVHRNGTLEIRNVRPTDTAEFICLARNDGGEAVMVVQLEVTGLLRRPIFKNPFNERIVSQ 317 Query: 306 SGNVARFTCTATGRPEPTMFWSV-EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 G C+A G P P + W+ G R F + H DG V+ D Sbjct: 318 IGKTIILNCSADGHPSPQIVWTFPNGTR---FSNKAEHGSHFHIRKDGSLVIRPGKEDAG 374 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF-PCTAIC 423 + R C A NY G ++ KL + + P I P + +F C + Sbjct: 375 NYR----CGARNYMG--YIE-KLIILEVGQK--PYIMTRPRGVIRSVSGEPLFLHCLSDG 425 Query: 424 TPEPIIAWYFEGEALIQN----HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK-YVW 478 +P P I W G + + R + +GTLV++ D G Y C A + G+ + Sbjct: 426 SPTPKIYWTIPGGHTLSHPQILGRHQLLENGTLVVEHTTLHDRGNYICRARNDAGEAVII 485 Query: 479 SGALLVDSPIN------PNIHFFRAADVS---SLPGPPTKPITHNVTDTSVTLSWSQNNK 529 ++V P PN+ R + + G P IT + D SV S Q Sbjct: 486 VPVVIVAYPPRITIGPLPNVKATRGTPLQLSCAAIGIPKPEITWELPDRSVLSSTQQGRP 545 Query: 530 IGSSSILGYQVEVFSRETLS 549 G + + R ++S Sbjct: 546 TGGELLHPQGTLIIQRPSVS 565 Score = 94.3 bits (224), Expect = 2e-17 Identities = 79/285 (27%), Positives = 128/285 (44%), Gaps = 36/285 (12%) Query: 216 GSSVTFQCRVGGDPLPDVLWR-------RSAGGGNMPLG----RVKVLDDGSLRLDNVIL 264 G+ V C+ G P P++ W SA ++ G R + D+G+L L+ V + Sbjct: 19 GNGVKVDCKASGAPKPEISWGLPDGTMVSSAFQADVSSGGQAQRYTLFDNGTLYLNQVSI 78 Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS--VNVESGNVARFTCTATGRPEP 322 ++EG+Y C AEN +G + +++V + P+ V+ G RF C A G P+P Sbjct: 79 SEEGDYICYAENHLGKDEMTVHISVMTVTPVIHPPSQTYARVKPGGSIRFDCEAVGEPKP 138 Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382 +FW + N +I R H D + + ++DT + VC A N AG + Sbjct: 139 KIFWMLPTN-DVIAASNERYLVHVNGSLD-IRDIRVSDTGE------YVCMARNPAGENR 190 Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA------VFPCTAICTPEPIIAWYFEGE 436 KL D D PP+I N+T+ IK +A + C A P P I W Sbjct: 191 KVYKL----DIDGNPPVINGHRQNRTV-IKDVAAKFSRKLIDCKAEGNPTPSITWIMPDN 245 Query: 437 ALIQ----NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477 + R NV +GTL ++++ +D+ + C+A + G+ V Sbjct: 246 IFLTVPYFGSRINVHRNGTLEIRNVRPTDTAEFICLARNDGGEAV 290 Score = 89.4 bits (212), Expect = 5e-16 Identities = 80/274 (29%), Positives = 111/274 (40%), Gaps = 23/274 (8%) Query: 31 LNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRATHGRV----HSDAGVYWC 85 LNC A G PSP I W + G + G F +R V DAG Y C Sbjct: 324 LNCSADGHPSPQIVWTFPNGTRFSNKAEH-----GSHFHIRKDGSLVIRPGKEDAGNYRC 378 Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPESK-QSAQGDTVVLECLPPRGSPEPNVYWK- 143 A N G + L V + P +S G+ + L CL GSP P +YW Sbjct: 379 GARNYMGYIE-KLIILEVGQ-KPYIMTRPRGVIRSVSGEPLFLHCLSD-GSPTPKIYWTI 435 Query: 144 KNGQTLLFDGDSRMH-LVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKP 202 G TL H L++ G LV++ D G Y C ARN AG + + + P Sbjct: 436 PGGHTLSHPQILGRHQLLENGTLVVEHTTLHDRGNYICRARNDAGEAVIIVPVVIVAYPP 495 Query: 203 YLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRR------SAGGGNMPLGRVKVLDDG 255 + GP +V A G+ + C G P P++ W S+ P G + G Sbjct: 496 RITIGPLPNVKATRGTPLQLSCAAIGIPKPEITWELPDRSVLSSTQQGRPTGGELLHPQG 555 Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 +L + ++D G Y C A+N +G S Y+ V Sbjct: 556 TLIIQRPSVSDTGRYKCLAKNYLGIDSKVTYVRV 589 Score = 60.5 bits (140), Expect = 3e-07 Identities = 57/191 (29%), Positives = 86/191 (45%), Gaps = 19/191 (9%) Query: 9 GEAPYIIEQPLDVTVA-RHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67 G+ PYI+ +P V + +P L+C + GSP+P I W G +S H IL L Sbjct: 396 GQKPYIMTRPRGVIRSVSGEPLFLHCLSDGSPTPKIYWTIPGGHTLS--HPQILGRHQLL 453 Query: 68 ---FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGD 123 L H +H D G Y C A N G A + VA + P + ++ +G Sbjct: 454 ENGTLVVEHTTLH-DRGNYICRARNDAGEAVIIVPVVIVAY-PPRITIGPLPNVKATRGT 511 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFD-------GDSRMHLVDGGNLVIQDARQTDAG 176 + L C G P+P + W+ +++L G +H G L+IQ +D G Sbjct: 512 PLQLSCAAI-GIPKPEITWELPDRSVLSSTQQGRPTGGELLH--PQGTLIIQRPSVSDTG 568 Query: 177 RYQCIARNAAG 187 RY+C+A+N G Sbjct: 569 RYKCLAKNYLG 579 Score = 53.2 bits (122), Expect = 4e-05 Identities = 48/181 (26%), Positives = 81/181 (44%), Gaps = 17/181 (9%) Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRD-----KYHATAVFDGVTVLTI 358 V GN + C A+G P+P + W + + T++ D + +FD T L + Sbjct: 16 VTYGNGVKVDCKASGAPKPEISWGLP-DGTMVSSAFQADVSSGGQAQRYTLFDNGT-LYL 73 Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK--SMAV 416 N ++ +C A N+ G + ++TV P+I + PS +K Sbjct: 74 NQVSISE-EGDYICYAENHLG----KDEMTVHISVMTVTPVI-HPPSQTYARVKPGGSIR 127 Query: 417 FPCTAICTPEPIIAWYFEGEALI--QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 F C A+ P+P I W +I N R V +G+L ++D+ SD+G Y C+A + G Sbjct: 128 FDCEAVGEPKPKIFWMLPTNDVIAASNERYLVHVNGSLDIRDIRVSDTGEYVCMARNPAG 187 Query: 475 K 475 + Sbjct: 188 E 188 >UniRef50_Q94155 Cluster: Unc-40 protein; n=2; Caenorhabditis|Rep: Unc-40 protein - Caenorhabditis elegans Length = 1415 Score = 118 bits (284), Expect = 1e-24 Identities = 175/745 (23%), Positives = 293/745 (39%), Gaps = 91/745 (12%) Query: 109 EFRLEPESKQSA-QGDTVVLEC----LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG 163 +F +EP + + + +LEC R + + WK++G L SR+ ++ G Sbjct: 42 QFVMEPRRNVTVMESSSHLLECSYVLAHERLVHDVRIEWKRDGVLLSERTSSRIKVMSNG 101 Query: 164 NLVIQDARQTDAGRYQC---IARNAAGTRE-----SAIATLKI-HIKPYLITGPEDVVAQ 214 +L I+ + G YQC + + T + S ATL++ + + + + +A+ Sbjct: 102 SLWIESVSSAEEGTYQCAVHVTTKSDQTSDTWTFLSRKATLRLADLAKFELQAIDRTLAK 161 Query: 215 TGSSVTFQCRVGGDPLPDVLWRRS----AGGGNMPLGRVKVLDDGSLRLDNVILADEGEY 270 G F C + P P +W + GG + V +L + + EG Y Sbjct: 162 -GQPTAFHCLINSKPTPTAVWLHNDEPIVNGGEYHILPV----SNTLEISSTQSRHEGTY 216 Query: 271 SCEAENS-VGAVSASGYLTVYDPPSIN-----LSPNSVNVESGNVARFTCTATGRPEPTM 324 C E + S + LTV N +P VE G+ C P + Sbjct: 217 RCTVEGAGKRRSSQTARLTVTTETVSNELVFITTPRLQVVEQGDEFLLECLVASLIRPQV 276 Query: 325 FWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR 384 W ++ +R II G+ + +++ V+ +I DT C A N S R Sbjct: 277 RW-LKDSRQIIVDGVRIRRVGVSSIL--VSRASIEDT------GLYTCRASN-NDDSIDR 326 Query: 385 GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC-TAICTPEPIIAWYFEGEALIQNHR 443 S + R PP IT P+ + + C TA PE + WY GEA+I Sbjct: 327 ----AVSVEVRAPPRITTRPTTKVAVETADVELECGTAAARPEARVNWYKNGEAII-GSE 381 Query: 444 RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSL 503 V L + + ++D Y C+A + G S LLVD+P + ++ A S + Sbjct: 382 YFVIEPNRLRILGVVRADQAIYQCIAENDVGSEQASAQLLVDAPDSSSV-----AASSGV 436 Query: 504 PGPPTKPITHNVTDTS---VTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGW 560 P + P+ T + + + W + + +I+ Y +F ++ L NS Sbjct: 437 PMTSSAPLGLRSTSSGSRFINVEWDPPVQ-RNGNIMRY--HIFYKDNLIDRERMINS--- 490 Query: 561 VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGV 620 T + SL P Y+ V EN G+ SDS+ V + G Sbjct: 491 -------SSTSATLTSLQPSTMYLIRVTAENEAGM---GKFSDSLKVTTNKEQAVPGKVA 540 Query: 621 SNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEM 680 S +T D I +P L ++I FY + PL+ + E Sbjct: 541 SLTTTATGPETID-----IRWSPPSGGQPALRYKI--FYSHD-------PLE----KNEK 582 Query: 681 KTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEM 740 +T++ + + + + + KYT Y+ + G S++ +T D P PP+NI+ Sbjct: 583 ETLI-TTSTTHYTLHGMDKYTGYQIRIEAEGSNGSGLSSDTVKVRTQSDEPSAPPVNIQA 641 Query: 741 FILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNL 800 ++T+V + W PE + NG ITGY + A + + I+ T + T M NL Sbjct: 642 EADSSTSVRVSWDEPEEESVNGEITGYRLKYKTKARGAKGNTLVIDATAREYT---MGNL 698 Query: 801 TSGVSYSVQIAAETIIGLGPFSQKV 825 Y +++A G GPFS V Sbjct: 699 EPNTQYLIRMAVVNHNGTGPFSDWV 723 Score = 101 bits (243), Expect = 9e-20 Identities = 80/291 (27%), Positives = 129/291 (44%), Gaps = 15/291 (5%) Query: 17 QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV 76 Q +D T+A+ QP +C P+P W +V+ ILP + +T R Sbjct: 153 QAIDRTLAKGQPTAFHCLINSKPTPTAVWLHNDEPIVNGGEYHILPVSNTLEISSTQSR- 211 Query: 77 HSDAGVYWC--EATNSYGTARSRNATLHVAVLREE--FRLEPESKQSAQGDTVVLECLPP 132 H G Y C E ++++ T+ + E F P + QGD +LECL Sbjct: 212 HE--GTYRCTVEGAGKRRSSQTARLTVTTETVSNELVFITTPRLQVVEQGDEFLLECLVA 269 Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192 P V W K+ + ++ DG R+ V ++++ A D G Y C A N + + A Sbjct: 270 -SLIRPQVRWLKDSRQIIVDG-VRIRRVGVSSILVSRASIEDTGLYTCRASNNDDSIDRA 327 Query: 193 IATLKIHIKPYLITGPEDVVAQTGSSVTFQC-RVGGDPLPDVLWRRSAGGGNMPLG-RVK 250 ++ +++ P + T P VA + V +C P V W ++ G +G Sbjct: 328 VS-VEVRAPPRITTRPTTKVAVETADVELECGTAAARPEARVNWYKN---GEAIIGSEYF 383 Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301 V++ LR+ V+ AD+ Y C AEN VG+ AS L V P S +++ +S Sbjct: 384 VIEPNRLRILGVVRADQAIYQCIAENDVGSEQASAQLLVDAPDSSSVAASS 434 Score = 35.9 bits (79), Expect = 6.7 Identities = 46/169 (27%), Positives = 67/169 (39%), Gaps = 12/169 (7%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVA---QTLDDVPDGPPINIEMFILNTTTVH- 749 + LR T+YEF + G+ S +A +TL P P ++ + + H Sbjct: 906 VEGLRPATEYEFAVRAVASN--GQLSTWSMATRNRTLAAPPSSAPRDLTVLPAESGDPHS 963 Query: 750 --LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYS 807 L W PP+ NG I Y V A+K IN S ++NL +Y Sbjct: 964 SSLHWQPPKYS--NGEIEEYLVFYTDRASLADKDWT-INYVAGDKLSHQVSNLLPKANYF 1020 Query: 808 VQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFV 856 +I A G GPFS V + ++ L R+ G S +GD V Sbjct: 1021 FKIQARNEKGHGPFSSVVGYTPSGGAI-LSGKDRHNARGHGSAASGDTV 1068 >UniRef50_A7RNP0 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1874 Score = 117 bits (282), Expect = 2e-24 Identities = 85/291 (29%), Positives = 130/291 (44%), Gaps = 30/291 (10%) Query: 33 CRAGGSPSPAIRWYKGGVLVVSDTHRSI-LPAGGLFFLRATHGRVHSDAGVYWCEATNSY 91 C GSP P + WYK G ++ + + +P GGL + ++H Y CEA N Sbjct: 22 CNVTGSPMPTLTWYKNGSVIRNSRIQIFTMPYGGLIRIGPLRAKIHK--ATYECEADNGV 79 Query: 92 GTARSRNATL--HVAVLRE----EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145 G ++TL H A + P KQ GD V C G+P PN+ W K+ Sbjct: 80 GPPLRDSSTLIVHTASTKPAGFPRIAKHPSFKQRRSGDDVTFTCAAV-GTPTPNITWFKD 138 Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG---TRESAIATLKIHI-- 200 ++ + L DG L I D R++D G+Y C+ARNA G + ++ A L I++ Sbjct: 139 RLPIVLNDPRVSVLSDGRKLRITDLRESDNGKYSCVARNALGMVFSSQAMPARLFIYLTL 198 Query: 201 -----KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255 KP P+D + V +C G P P ++W G+ G+ +G Sbjct: 199 SVVRSKPEFTLRPQDKTVDPDTDVELKCSARGSPTPSIVWEVD---GSRISGQ-----NG 250 Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306 L + + G YSC A++++G V A Y+TV P PN+ ++ S Sbjct: 251 ELIIRGI--QRSGNYSCIADSNMGRVQAYAYVTVRLLPFAPSRPNAASITS 299 Score = 101 bits (241), Expect = 2e-19 Identities = 153/641 (23%), Positives = 254/641 (39%), Gaps = 100/641 (15%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD---DGSLR 258 P + P+D T V C V G P+P + W ++ G + R+++ G +R Sbjct: 1 PTVTLTPKDFAGVTRGFVYMICNVTGSPMPTLTWYKN--GSVIRNSRIQIFTMPYGGLIR 58 Query: 259 LDNV-ILADEGEYSCEAENSVG-AVSASGYLTVYDP-------PSINLSPNSVNVESGNV 309 + + + Y CEA+N VG + S L V+ P I P+ SG+ Sbjct: 59 IGPLRAKIHKATYECEADNGVGPPLRDSSTLIVHTASTKPAGFPRIAKHPSFKQRRSGDD 118 Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369 FTC A G P P + W + P + D + + DG L I D ++D+ Sbjct: 119 VTFTCAAVGTPTPNITWFKDR-----LPIVLNDP-RVSVLSDG-RKLRITDLRESDN-GK 170 Query: 370 IVCSAVNYAGSSF------VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423 C A N G F R + +T R P T P ++T+ + C+A Sbjct: 171 YSCVARNALGMVFSSQAMPARLFIYLTLSVVRSKPEFTLRPQDKTVDPDTDVELKCSARG 230 Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483 +P P I W +G R +G L+++ + + SG Y+C+A S G+ Sbjct: 231 SPTPSIVWEVDGS-------RISGQNGELIIRGIQR--SGNYSCIADSNMGR-------- 273 Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543 + + V LP P++P ++T ++ ++W G+ + Y+V+ Sbjct: 274 --------VQAYAYVTVRLLPFAPSRPNAASITSDAIKITWHPR---GAHVVTSYEVQY- 321 Query: 544 SRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603 L G W I VV L P +Y F V NS G S PS +++ Sbjct: 322 ---RLKGKTE------WQEITNVRGMQSLVVSGLRPFSSYEFRVFAVNSLGRSRPSLMAE 372 Query: 604 SVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMW--EILNFYYL 661 T + G+ N IEA + + K W I + Sbjct: 373 YTT-----SETKPGSAPRN----------------IEAMGVSDTSFKAGWLPPISANGRI 411 Query: 662 EGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNS 721 G +Y+ LD +E + ++ + +T L + T + F ++ + +G S Sbjct: 412 RGYRLYY-SLD--LLEDISQWRFMASSTNSTTVTGLTRQTTHFFRILAYNIAGDGPLSEV 468 Query: 722 RVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKS 781 +T VP G P ++++ +L++T + + WSPP +GI GY+V N + + Sbjct: 469 VAVKTQKGVP-GQPRSVQLSVLSSTAIRVTWSPPRYP-GDGIF-GYDVYYN----KSKQD 521 Query: 782 MVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFS 822 M + T IM LT Y V +AA++ G+GP S Sbjct: 522 MDTVIGAFQMNTKEIM-GLTPYTVYKVAVAAKSDKGVGPMS 561 Score = 89.4 bits (212), Expect = 5e-16 Identities = 66/219 (30%), Positives = 95/219 (43%), Gaps = 20/219 (9%) Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR-QTDAGRYQCIARNAAGTRESA 192 GSP P + W KNG + + GG + I R + Y+C A N G Sbjct: 26 GSPMPTLTWYKNGSVIRNSRIQIFTMPYGGLIRIGPLRAKIHKATYECEADNGVGPPLRD 85 Query: 193 IATLKIHIK-------PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 +TL +H P + P ++G VTF C G P P++ W + + Sbjct: 86 SSTLIVHTASTKPAGFPRIAKHPSFKQRRSGDDVTFTCAAVGTPTPNITWFKDRLPIVLN 145 Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASG--------YLT---VYDPP 293 RV VL DG LR+ ++ +D G+YSC A N++G V +S YLT V P Sbjct: 146 DPRVSVLSDGRKLRITDLRESDNGKYSCVARNALGMVFSSQAMPARLFIYLTLSVVRSKP 205 Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332 L P V+ C+A G P P++ W V+G+R Sbjct: 206 EFTLRPQDKTVDPDTDVELKCSARGSPTPSIVWEVDGSR 244 Score = 70.9 bits (166), Expect = 2e-10 Identities = 61/189 (32%), Positives = 90/189 (47%), Gaps = 26/189 (13%) Query: 30 TLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88 T C A G+P+P I W+K + +V++D S+L G LR T R SD G Y C A Sbjct: 120 TFTCAAVGTPTPNITWFKDRLPIVLNDPRVSVLSDGRK--LRITDLR-ESDNGKYSCVAR 176 Query: 89 NSYGTARSRNA---------TLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139 N+ G S A TL V + EF L P+ K V L+C RGSP P+ Sbjct: 177 NALGMVFSSQAMPARLFIYLTLSVVRSKPEFTLRPQDKTVDPDTDVELKC-SARGSPTPS 235 Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199 + W+ +G + G + G L+I+ ++ +G Y CIA + G R A A + + Sbjct: 236 IVWEVDGSRI--SGQN-------GELIIRGIQR--SGNYSCIADSNMG-RVQAYAYVTVR 283 Query: 200 IKPYLITGP 208 + P+ + P Sbjct: 284 LLPFAPSRP 292 Score = 66.9 bits (156), Expect = 3e-09 Identities = 47/186 (25%), Positives = 86/186 (46%), Gaps = 6/186 (3%) Query: 639 IEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLR 698 I+ DS T+++ W+ + GL +F + K + + + +L Sbjct: 580 IQGRSRDSTTLEISWDPPRPEHRNGLITHFTIKYRAKGQRGAKYLTVDATKTSVVLHNLD 639 Query: 699 KYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQ 758 K+T Y ++ K+ +G S+ T +DVP+G P ++ + + N+TT+ +KW+PP + Sbjct: 640 KFTNYFIWVQASTKQGDGPFSDKHTVSTAEDVPNGAPRDVRIRVHNSTTMTVKWNPPTTK 699 Query: 759 LQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATS-----LIMTNLTSGVSYSVQIAAE 813 Q+G I GY V +D N+ + S + +T L +Y +++AA Sbjct: 700 -QDGKILGYMVFYTRVDDQGNQLRPPAQPESKDSMSEENHKVHLTGLAPETTYQIEVAAY 758 Query: 814 TIIGLG 819 TI G G Sbjct: 759 TIKGDG 764 Score = 64.1 bits (149), Expect = 2e-08 Identities = 49/186 (26%), Positives = 86/186 (46%), Gaps = 7/186 (3%) Query: 639 IEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLR 698 ++ + + S I++ W Y +G+F Y + + +M T++ + ++ EI L Sbjct: 484 VQLSVLSSTAIRVTWSPPR-YPGDGIFGYDVYYNKS--KQDMDTVIGAFQMNTKEIMGLT 540 Query: 699 KYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQ 758 YT Y+ + K G S A+T +D P P NI+ ++TT+ + W PP + Sbjct: 541 PYTVYKVAVAAKSDKGVGPMSFVLTARTDEDRPSDAPQNIQGRSRDSTTLEISWDPPRPE 600 Query: 759 LQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGL 818 +NG+IT + + K + T TS+++ NL +Y + + A T G Sbjct: 601 HRNGLITHFTIKYRAKGQRGAKYLTVDAT----KTSVVLHNLDKFTNYFIWVQASTKQGD 656 Query: 819 GPFSQK 824 GPFS K Sbjct: 657 GPFSDK 662 Score = 62.9 bits (146), Expect = 5e-08 Identities = 41/147 (27%), Positives = 69/147 (46%), Gaps = 7/147 (4%) Query: 679 EMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINI 738 +MK I + + + SL Y F + K P SR + P GPP+N+ Sbjct: 831 KMKEIKFKSHTTKQKFQSLANGIWY-LFNVSLRTKAGWSPETSRWIEIPPGPPSGPPLNV 889 Query: 739 EMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANK--SMVAINTTVHQATSLI 796 +++T+V + WS P++ + G I GY+V+ N PANK + N T ++ Sbjct: 890 RAVAVSSTSVEVTWSAPDIWNRGGPILGYSVMYN----PANKRGDVTVKNVTSPNIFKVV 945 Query: 797 MTNLTSGVSYSVQIAAETIIGLGPFSQ 823 + L Y V++ A ++G+GP S+ Sbjct: 946 LKRLKKFREYEVRVRAIGMLGMGPASE 972 Score = 52.8 bits (121), Expect = 5e-05 Identities = 51/220 (23%), Positives = 90/220 (40%), Gaps = 15/220 (6%) Query: 641 ATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKY 700 A I S IK+ W + + + +R + + E + I + + ++ LR + Sbjct: 294 AASITSDAIKITWHPRGAHVVTSYEVQYR----LKGKTEWQEITNVRGMQSLVVSGLRPF 349 Query: 701 TKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQ 760 + YEF + +PS T + P P NIE ++ T+ W PP Sbjct: 350 SSYEFRVFAVNSLGRSRPSLMAEYTTSETKPGSAPRNIEAMGVSDTSFKAGWLPP--ISA 407 Query: 761 NGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGP 820 NG I GY + + LD+ + S + +T+ +T LT ++ +I A I G GP Sbjct: 408 NGRIRGYRLYYS-LDLLEDISQWRFMASSTNSTT--VTGLTRQTTHFFRILAYNIAGDGP 464 Query: 821 FSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETW 860 S+ V G P + ++S+++ + TW Sbjct: 465 LSEVVAVKTQKGVPG------QPRSVQLSVLSSTAIRVTW 498 >UniRef50_UPI00015A4156 Cluster: Neogenin precursor.; n=1; Danio rerio|Rep: Neogenin precursor. - Danio rerio Length = 1088 Score = 117 bits (281), Expect = 2e-24 Identities = 84/285 (29%), Positives = 128/285 (44%), Gaps = 13/285 (4%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P + QP V+V L+C P RW + V D+ LP+G L A Sbjct: 7 PRFLSQPEGVSVRSGGTEMLSCEVTEELVPFTRWDRDARPVELDSRVIQLPSGALVISNA 66 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHV-----AVLREEFRLEPESKQSAQGDTVV 126 + +DAG+Y C + A L V A + E P + G++V+ Sbjct: 67 SQ----ADAGLYRCTIDGLGPPKTTEEAELQVVTDSGAGEKLETLQGPVAVAKVVGESVL 122 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186 L C+ +G P P + W N Q + + R ++ GG+L I + + DAG Y C A + Sbjct: 123 LPCVM-KGHPIPAIRWTFNDQPIE-EAHERFSVIGGGSLQIVNLTEEDAGIYVCQADSGN 180 Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 T E A L +H+ P +T P + AQ + F+C V G P P V W + G +P Sbjct: 181 MTSEIQ-AELTVHVPPRFLTRPSNTYAQESMDIIFECDVTGSPPPTVKWMKD-GDTVIPS 238 Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291 +++ +L++ ++ +DEG Y C AEN G V AS L + D Sbjct: 239 DYFRIVKQHNLQVLGLVKSDEGFYQCLAENDAGNVQASAQLIILD 283 Score = 90.6 bits (215), Expect = 2e-16 Identities = 64/231 (27%), Positives = 98/231 (42%), Gaps = 9/231 (3%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169 F +PE G T +L C P W ++ + + + DSR+ + G LVI + Sbjct: 9 FLSQPEGVSVRSGGTEMLSCEVTE-ELVPFTRWDRDARPV--ELDSRVIQLPSGALVISN 65 Query: 170 ARQTDAGRYQCIARNAAGTRESAIATLKIHI------KPYLITGPEDVVAQTGSSVTFQC 223 A Q DAG Y+C + + A L++ K + GP V G SV C Sbjct: 66 ASQADAGLYRCTIDGLGPPKTTEEAELQVVTDSGAGEKLETLQGPVAVAKVVGESVLLPC 125 Query: 224 RVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSA 283 + G P+P + W + R V+ GSL++ N+ D G Y C+A++ Sbjct: 126 VMKGHPIPAIRWTFNDQPIEEAHERFSVIGGGSLQIVNLTEEDAGIYVCQADSGNMTSEI 185 Query: 284 SGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334 LTV+ PP P++ + F C TG P PT+ W +G+ I Sbjct: 186 QAELTVHVPPRFLTRPSNTYAQESMDIIFECDVTGSPPPTVKWMKDGDTVI 236 Score = 74.1 bits (174), Expect = 2e-11 Identities = 53/195 (27%), Positives = 88/195 (45%), Gaps = 12/195 (6%) Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPAGGL 66 +GE ++ P+ V + L C G P PAIRW + + + S++ G L Sbjct: 100 AGEKLETLQGPVAVAKVVGESVLLPCVMKGHPIPAIRWTFNDQPIEEAHERFSVIGGGSL 159 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTV 125 + T DAG+Y C+A + T+ + T+HV F P + + + + Sbjct: 160 QIVNLTE----EDAGIYVCQADSGNMTSEIQAELTVHVP---PRFLTRPSNTYAQESMDI 212 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 + EC GSP P V W K+G T++ +V NL + ++D G YQC+A N Sbjct: 213 IFEC-DVTGSPPPTVKWMKDGDTVI--PSDYFRIVKQHNLQVLGLVKSDEGFYQCLAEND 269 Query: 186 AGTRESAIATLKIHI 200 AG +++ + + I Sbjct: 270 AGNVQASAQLIILDI 284 Score = 71.3 bits (167), Expect = 1e-10 Identities = 68/290 (23%), Positives = 111/290 (38%), Gaps = 22/290 (7%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDN 261 P ++ PE V ++G + C V + +P W R A + RV L G+L + N Sbjct: 7 PRFLSQPEGVSVRSGGTEMLSCEVTEELVPFTRWDRDARPVELD-SRVIQLPSGALVISN 65 Query: 262 VILADEGEYSCEAEN-SVGAVSASGYLTVYDPPSIN------LSPNSVNVESGNVARFTC 314 AD G Y C + + L V P +V G C Sbjct: 66 ASQADAGLYRCTIDGLGPPKTTEEAELQVVTDSGAGEKLETLQGPVAVAKVVGESVLLPC 125 Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374 G P P + W+ + + +V G ++ +N T+++ VC A Sbjct: 126 VMKGHPIPAIRWTFNDQPI-------EEAHERFSVIGGGSLQIVNLTEED--AGIYVCQA 176 Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFE 434 + +S ++ +LTV PP +T PSN +F C +P P + W + Sbjct: 177 DSGNMTSEIQAELTVHV----PPRFLTR-PSNTYAQESMDIIFECDVTGSPPPTVKWMKD 231 Query: 435 GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 G+ +I + + L + L KSD G Y C+A + G S L++ Sbjct: 232 GDTVIPSDYFRIVKQHNLQVLGLVKSDEGFYQCLAENDAGNVQASAQLII 281 Score = 68.9 bits (161), Expect = 8e-10 Identities = 31/84 (36%), Positives = 51/84 (60%), Gaps = 2/84 (2%) Query: 688 DVSG--FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNT 745 DVSG + +TSL+K+T+Y F ++ + K G + +TL DVP P N+ + +LN+ Sbjct: 444 DVSGLSYTMTSLKKFTEYSFRVVAYNKHGPGVSTEDVTVRTLSDVPSAAPQNLTLDVLNS 503 Query: 746 TTVHLKWSPPELQLQNGIITGYNV 769 T++ ++W PP NG +TGY + Sbjct: 504 TSIMVRWQPPPAGSLNGELTGYKL 527 Score = 51.6 bits (118), Expect = 1e-04 Identities = 55/227 (24%), Positives = 92/227 (40%), Gaps = 17/227 (7%) Query: 612 NSLWEGTGVSNSTEYRNNILTDHIVEL----IEATPIDSKTIKLMWE----ILNFYYLEG 663 N++ EG + NS R D L ++A+ + T+K+ W N + Sbjct: 670 NNMGEGVPIYNSATTRPQSAPDPTPMLPPVGVQASVLSHDTVKVSWADNSLAKNQKITDA 729 Query: 664 LFIYFRPLDNITIEYEMKTILHSNDVSGFE-ITSLRKYTKYEFFLIPFYKKFEGKPSNSR 722 + R NI + K +N S F +++L+ T YEF ++ + S + Sbjct: 730 RYYTIRWKTNIPANTKYKM---ANTTSLFHTVSALKPNTLYEFSVMVTKNRRSSTWSMTA 786 Query: 723 VAQTLDDVPDGPPINIEMFIL--NTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANK 780 + T + +P P ++ + N +++ W PP NG ITGY ++ DV A Sbjct: 787 HSTTHESIPSSAPKDVTVISKEGNPRIININWQPPTEA--NGKITGY-IIYYSTDVNAEV 843 Query: 781 SMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYF 827 + V + + LT SY +I A G+GP S V F Sbjct: 844 HDWVVEPVVGNRLTHQIQGLTLDTSYFFKIQARNSKGMGPMSDAVQF 890 Score = 39.9 bits (89), Expect = 0.41 Identities = 27/117 (23%), Positives = 49/117 (41%), Gaps = 8/117 (6%) Query: 674 ITIEYEMKTILHSN-DVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPD 732 +T++Y+ + N D S + +L+ Y +P Y +P ++ D P Sbjct: 642 VTLDYKQRFYSIDNLDASSHYVITLKAYNNMGEG-VPIYNSATTRPQSAP-----DPTPM 695 Query: 733 GPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNW-LDVPANKSMVAINTT 788 PP+ ++ +L+ TV + W+ L I + W ++PAN NTT Sbjct: 696 LPPVGVQASVLSHDTVKVSWADNSLAKNQKITDARYYTIRWKTNIPANTKYKMANTT 752 >UniRef50_Q4RRR9 Cluster: Chromosome 16 SCAF15002, whole genome shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 16 SCAF15002, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 875 Score = 117 bits (281), Expect = 2e-24 Identities = 112/421 (26%), Positives = 174/421 (41%), Gaps = 37/421 (8%) Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPE 137 DAGVY C ATN A S T+ V + ++ FR P ++ +GD + C SP Sbjct: 80 DAGVYKCIATNGDQQAES---TVKVKIFQKITFRNAPSPQEFTEGDIADIIC-DIESSPP 135 Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR-NAAGTRESAIATL 196 P V WK G+ + D D R + +L I+ ++TD G Y C R + G + + + Sbjct: 136 PTVLWKYKGRKIQMDKDVRFKELSNNHLQIRGIKKTDEGPYTCEGRLMSRGEIDFRVIKV 195 Query: 197 KIHIKPYLITGPEDV--VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLD 253 +++ P + +V A G V C V G P P V W R+ G + G + + Sbjct: 196 IVNVLPTIRVWQTEVNATADVGQPVKLTCAVDGYPEPMVTWTRN--GVVLEAGEKYSFNE 253 Query: 254 DGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-------PPSINLSPNSVNVE 305 DGS + L V DEGEY+C A+N G L V+D P I N+ +E Sbjct: 254 DGSEMTLLEVAKLDEGEYTCIAKNKAGESEQELSLRVFDSVLVFAVKPKITYIINTTALE 313 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365 + TC A+G P PT+ WS GN +F ++ H ++ + + +D Sbjct: 314 TEEQVTLTCEASGDPTPTISWSYGGN---VF--SEGEQAHLNRIYQSLDGNVVTRSDARV 368 Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDD------RPPPIITNGPSNQTLPIKSMAVFPC 419 S + AG + + D+ R P I + T ++ + C Sbjct: 369 SSLNLKHVKYTDAGQYLCTARSAIGEDEQSAYLEVRYAPKIHGDVAVYTWEENAVNI-SC 427 Query: 420 TAICTPEPI-IAWYFEGEALIQNHRRNV-----TNDGTLVLKDLDKSDSGTYTCVASSRH 473 P + I W +G L + NV + L + ++D G+Y C AS+ Sbjct: 428 EVQAHPSDVSIVWLRDGLQLPNANATNVKIFRTPSSSYLQINPGSENDFGSYNCTASNEL 487 Query: 474 G 474 G Sbjct: 488 G 488 Score = 81.0 bits (191), Expect = 2e-13 Identities = 92/352 (26%), Positives = 133/352 (37%), Gaps = 35/352 (9%) Query: 165 LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR 224 L + A DAG Y+CIA N ES + +KI K P G C Sbjct: 71 LTLYKAGTEDAGVYKCIATNGDQQAESTV-KVKIFQKITFRNAPSPQEFTEGDIADIICD 129 Query: 225 VGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAE-NSVGAVS 282 + P P VLW+ M R K L + L++ + DEG Y+CE S G + Sbjct: 130 IESSPPPTVLWKYKGRKIQMDKDVRFKELSNNHLQIRGIKKTDEGPYTCEGRLMSRGEID 189 Query: 283 ASGYLTVYDP-PSINLSPNSVN--VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGM 339 + + P+I + VN + G + TC G PEP + W+ G ++ G Sbjct: 190 FRVIKVIVNVLPTIRVWQTEVNATADVGQPVKLTCAVDGYPEPMVTWTRNG--VVLEAG- 246 Query: 340 SRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD--DDRPP 397 +KY +T+L + D+ + C A N AG S L V Sbjct: 247 --EKYSFNEDGSEMTLLEVAKLDEGE----YTCIAKNKAGESEQELSLRVFDSVLVFAVK 300 Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN-----DGTL 452 P IT + L + C A P P I+W + G + + ++ DG + Sbjct: 301 PKITYIINTTALETEEQVTLTCEASGDPTPTISWSYGGNVFSEGEQAHLNRIYQSLDGNV 360 Query: 453 V-----------LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIH 493 V LK + +D+G Y C A S G+ S L V P IH Sbjct: 361 VTRSDARVSSLNLKHVKYTDAGQYLCTARSAIGEDEQSAYLEV--RYAPKIH 410 Score = 66.1 bits (154), Expect = 6e-09 Identities = 79/295 (26%), Positives = 113/295 (38%), Gaps = 36/295 (12%) Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86 QP L C G P P + W + GV++ + S G L D G Y C Sbjct: 218 QPVKLTCAVDGYPEPMVTWTRNGVVLEAGEKYSFNEDGSEMTLLEV---AKLDEGEYTCI 274 Query: 87 ATNSYGTARSRNATLHVAVLREEFRLEPE------SKQSAQGDTVVLECLPPRGSPEPNV 140 A N G + + +L V F ++P+ + + V L C G P P + Sbjct: 275 AKNKAGES-EQELSLRVFDSVLVFAVKPKITYIINTTALETEEQVTLTC-EASGDPTPTI 332 Query: 141 YWKKNGQTLLFDGDSRMHL------VDGGNLVIQDAR----------QTDAGRYQCIARN 184 W G +F + HL +DG + DAR TDAG+Y C AR+ Sbjct: 333 SWSYGGN--VFSEGEQAHLNRIYQSLDGNVVTRSDARVSSLNLKHVKYTDAGQYLCTARS 390 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRRSA-GGG 242 A G E + A L++ P I G V ++V C V P ++W R Sbjct: 391 AIGEDEQS-AYLEVRYAP-KIHGDVAVYTWEENAVNISCEVQAHPSDVSIVWLRDGLQLP 448 Query: 243 NMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294 N VK+ S L+++ D G Y+C A N +G S L + PS Sbjct: 449 NANATNVKIFRTPSSSYLQINPGSENDFGSYNCTASNELGTESKEFLLIQAEVPS 503 Score = 61.7 bits (143), Expect = 1e-07 Identities = 84/378 (22%), Positives = 144/378 (38%), Gaps = 32/378 (8%) Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG---NMPLG 247 S++ +L++ I P T E G S F C V G + W +G N P Sbjct: 7 SSVVSLEVQITP---THGE---ISLGESKFFMCEVAG-VAKHIDWFGPSGDRIEQNSPDI 59 Query: 248 RVKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305 V D+ S L L D G Y C A N ++ + ++ + +P+ Sbjct: 60 TVTRNDESSSILTLYKAGTEDAGVYKCIATNGDQQAESTVKVKIFQKITFRNAPSPQEFT 119 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365 G++A C P PT+ W +G + M +D + + + I TD+ Sbjct: 120 EGDIADIICDIESSPPPTVLWKYKGRKI----QMDKDVRFKELSNNHLQIRGIKKTDEGP 175 Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425 T ++ F K+ V P + N T + C P Sbjct: 176 Y--TCEGRLMSRGEIDFRVIKVIVNV---LPTIRVWQTEVNATADVGQPVKLTCAVDGYP 230 Query: 426 EPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 EP++ W G L + + DG+ + L ++ K D G YTC+A ++ G+ +L V Sbjct: 231 EPMVTWTRNGVVLEAGEKYSFNEDGSEMTLLEVAKLDEGEYTCIAKNKAGESEQELSLRV 290 Query: 485 -DS----PINPNIHFFRAADVSSLPGPPTKPITHNVT-DTSVTLSWSQNNKIGSSSILGY 538 DS + P I + + ++L +T + D + T+SWS + S + Sbjct: 291 FDSVLVFAVKPKITYI--INTTALETEEQVTLTCEASGDPTPTISWSYGGNVFSEGEQAH 348 Query: 539 QVEVFSRETLSGNNTPRN 556 ++ ++L GN R+ Sbjct: 349 LNRIY--QSLDGNVVTRS 364 >UniRef50_Q8NFA8 Cluster: Transmembrane receptor PTK7-2; n=18; Euteleostomi|Rep: Transmembrane receptor PTK7-2 - Homo sapiens (Human) Length = 1030 Score = 117 bits (281), Expect = 2e-24 Identities = 87/321 (27%), Positives = 146/321 (45%), Gaps = 23/321 (7%) Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT------HRSILPAGGLF 67 ++ P DV VAR++ A +C+ P P+++W +++ R+ + A G Sbjct: 227 VVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSL 286 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127 L R +AG+Y C G ATLH+A + + EP + + V Sbjct: 287 LLTQVRPR---NAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVT- 342 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 CLPP+G PEP+V+W+ G L G R++ G LV+ + ++DAG Y C A N AG Sbjct: 343 -CLPPKGLPEPSVWWEHAGVRLPTHG--RVYQ-KGHELVLANIAESDAGVYTCHAANLAG 398 Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247 R + + + P + P+D + G C P P V+W R+ + Sbjct: 399 QRRQDV-NITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISED-S 456 Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN--LSPNSVNVE 305 R +V +G+LR+++V + D Y C + G++ A + V D S+ ++ N+ + Sbjct: 457 RFEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLDGSSLPEWVTDNAGTLH 516 Query: 306 SGNVAR-----FTCTATGRPE 321 V R +TC A+ P+ Sbjct: 517 FARVTRDDAGNYTCIASNGPQ 537 Score = 101 bits (243), Expect = 9e-20 Identities = 126/479 (26%), Positives = 187/479 (39%), Gaps = 44/479 (9%) Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73 I+QP + + A L C +P P + W G V DT R L F A Sbjct: 35 IKQPSSQDALQGRRALLRCEVE-APGPVHVYWLLDGA-PVQDTERRFAQGSSLSF--AAV 90 Query: 74 GRVHSDAGVYWCEATNSYG--TARSRNATLHVAVLREE--FRLEPESKQSAQGDT-VVLE 128 R+ D+G + C A + ARS NA+ ++ + P S+ Q T V L Sbjct: 91 DRLQ-DSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 149 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAA 186 C G P P W ++G T L DG S H V NL ++ A +G Y C A +A Sbjct: 150 CHID-GHPRPTYQWFRDG-TPLSDGQSN-HTVSSKERNLTLRPAGPEHSGLYSCCAHSAF 206 Query: 187 GTR-ESAIATLKIHIKPY--LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSA 239 G S TL I + + ++ P+DVV F C+ P P + W Sbjct: 207 GQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPI 266 Query: 240 GGGNMP--LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSIN 296 + P L R V +GSL L V + G Y C + G + L + + + Sbjct: 267 TNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMP 326 Query: 297 LSPNSVNVESGNVARFTCTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355 L V +G+ R TC G PEP+++W G R P R V+ Sbjct: 327 LFEPRV-FTAGSEERVTCLPPKGLPEPSVWWEHAGVR---LPTHGR-------VYQKGHE 375 Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415 L + + ++D+ C A N AG +TV + P P + L Sbjct: 376 LVLANIAESDA-GVYTCHAANLAGQRRQDVNITVAT-----VPSWLKKPQDSQLEEGKPG 429 Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 C TP+P + WY + ++ R V +GTL + ++ D Y C++S+ G Sbjct: 430 YLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCMSSTPAG 488 Score = 88.6 bits (210), Expect = 9e-16 Identities = 88/328 (26%), Positives = 134/328 (40%), Gaps = 23/328 (7%) Query: 12 PYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFL 69 P +++ P + + TL C G P P +W++ G L ++ ++ L Sbjct: 128 PVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTL 187 Query: 70 RATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFR---LEPESKQSAQGDTV 125 R G HS G+Y C A +++G A S+N TL +A E F L P+ A+ + Sbjct: 188 RPA-GPEHS--GLYSCCAHSAFGQACSSQNFTLSIA--DESFARVVLAPQDVVVARYEEA 242 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL-----VDGGNLVIQDARQTDAGRYQC 180 + C P P++ W +T + + HL G+L++ R +AG Y+C Sbjct: 243 MFHC-QFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRC 301 Query: 181 IARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239 I + G ATL + I+ + P A + VT G P P V W + Sbjct: 302 IGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTC-LPPKGLPEPSVWWEHA- 359 Query: 240 GGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298 G +P GRV L L N+ +D G Y+C A N G +TV PS Sbjct: 360 -GVRLPTHGRV-YQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKK 417 Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFW 326 P +E G C P+PT+ W Sbjct: 418 PQDSQLEEGKPGYLDCLTQATPKPTVVW 445 Score = 83.0 bits (196), Expect = 4e-14 Identities = 97/384 (25%), Positives = 151/384 (39%), Gaps = 36/384 (9%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169 F +P S+ + QG +L C P +VYW +G + D+ G +L Sbjct: 34 FIKQPSSQDALQGRRALLRCEVEAPGPV-HVYWLLDGAPVQ---DTERRFAQGSSLSFAA 89 Query: 170 A-RQTDAGRYQCIARNAAGTRESAIATLKIHIK-----PYLITGP-EDVVAQTGSSVTFQ 222 R D+G +QC+AR+ E+ A +IK P ++ P + Q + VT + Sbjct: 90 VDRLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 149 Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVG-A 280 C + G P P W R + V + +L L G YSC A ++ G A Sbjct: 150 CHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQA 209 Query: 281 VSASGY-LTVYDPP--SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337 S+ + L++ D + L+P V V A F C + +P P++ W E I Sbjct: 210 CSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNR 269 Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV-RGKLTVTSDDDRP 396 AT +G +LT + + C G + L + +D P Sbjct: 270 SRPPHLRRATVFANGSLLLT---QVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMP 326 Query: 397 ---PPIITNGPSNQT--LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT 451 P + T G + LP K + PEP + W G L H R Sbjct: 327 LFEPRVFTAGSEERVTCLPPKGL----------PEPSVWWEHAGVRL-PTHGRVYQKGHE 375 Query: 452 LVLKDLDKSDSGTYTCVASSRHGK 475 LVL ++ +SD+G YTC A++ G+ Sbjct: 376 LVLANIAESDAGVYTCHAANLAGQ 399 Score = 74.9 bits (176), Expect = 1e-11 Identities = 53/143 (37%), Positives = 71/143 (49%), Gaps = 12/143 (8%) Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122 AG L F R T DAG Y C A+N + L VAV F++EPE QG Sbjct: 512 AGTLHFARVTR----DDAGNYTCIASNGPQGQIRAHVQLTVAVFIT-FKVEPERTTVYQG 566 Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS---RMHLVDGGNLVIQDARQTDAGRYQ 179 T +L+C +G P+P + WK G+ + D RMH+ G+LVI D D+GRY Sbjct: 567 HTALLQC-EAQGDPKPLIQWK--GKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYT 623 Query: 180 CIARNAAGTRESAIATLKIHIKP 202 CIA N+ + + A L + KP Sbjct: 624 CIAGNSCNIKHTE-APLYVVDKP 645 Score = 60.1 bits (139), Expect = 4e-07 Identities = 44/148 (29%), Positives = 60/148 (40%), Gaps = 4/148 (2%) Query: 150 LFDGDSRMHLV--DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG 207 + DG S V + G L + DAG Y CIA N + A L + + Sbjct: 498 VLDGSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFITFKVE 557 Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSAGGGNMPLG-RVKVLDDGSLRLDNVILA 265 PE G + QC GDP P + W+ + LG R+ + +GSL + +V Sbjct: 558 PERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPE 617 Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPP 293 D G Y+C A NS L V D P Sbjct: 618 DSGRYTCIAGNSCNIKHTEAPLYVVDKP 645 Score = 49.6 bits (113), Expect = 5e-04 Identities = 44/153 (28%), Positives = 61/153 (39%), Gaps = 11/153 (7%) Query: 255 GSLRLDNVILADEGEYSCEAENSV-GAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313 G+L V D G Y+C A N G + A LTV + + P V G+ A Sbjct: 513 GTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQ 572 Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373 C A G P+P + W +G I+ P + H +F + L I+D DS C Sbjct: 573 CEAQGDPKPLIQW--KGKDRILDPTKLGPRMH---IFQNGS-LVIHDVAPEDS-GRYTCI 625 Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN 406 A N L V D+P P + GP + Sbjct: 626 AGNSCNIKHTEAPLYVV---DKPVPEESEGPGS 655 Score = 44.4 bits (100), Expect = 0.019 Identities = 27/89 (30%), Positives = 45/89 (50%), Gaps = 4/89 (4%) Query: 404 PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH---RRNVTNDGTLVLKDLDKS 460 P T+ A+ C A P+P+I W + L R ++ +G+LV+ D+ Sbjct: 558 PERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPE 617 Query: 461 DSGTYTCVA-SSRHGKYVWSGALLVDSPI 488 DSG YTC+A +S + K+ + +VD P+ Sbjct: 618 DSGRYTCIAGNSCNIKHTEAPLYVVDKPV 646 Score = 38.3 bits (85), Expect = 1.3 Identities = 16/64 (25%), Positives = 30/64 (46%) Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62 D +T P +++P D + +P L+C +P P + WY+ +L+ D+ + Sbjct: 403 DVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFK 462 Query: 63 AGGL 66 G L Sbjct: 463 NGTL 466 >UniRef50_Q4KMQ7 Cluster: NRCAM protein; n=10; Euteleostomi|Rep: NRCAM protein - Homo sapiens (Human) Length = 771 Score = 117 bits (281), Expect = 2e-24 Identities = 134/497 (26%), Positives = 197/497 (39%), Gaps = 57/497 (11%) Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175 +K+ +G+ + LEC+ G P P +YW K L + ++ L I + D+ Sbjct: 273 NKEELRGNVLSLECIA-EGLPTPIIYWAKEDGML--PKNRTVYKNFEKTLQIIHVSEADS 329 Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235 G YQCIA+NA G I+ +++ PY IT P+++V G T CR G+P P + W Sbjct: 330 GNYQCIAKNALGAIHHTIS-VRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISW 388 Query: 236 RRSAGGGNM-PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-DPP 293 + + P + +D ++ NV Y C A N G + A+ ++ V +PP Sbjct: 389 LTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPP 448 Query: 294 SINLSPNSV-NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA-VFD 351 I N++ V + A C G P PT+ W F G H V Sbjct: 449 RILTPANTLYQVIANRPALLDCAFFGSPLPTIEW---------FKGAKGSALHEDIYVLH 499 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411 L I K DS T C A N G + L + + I P + Sbjct: 500 ENGTLEIPVAQK-DSTGTYTCVARNKLGMAKNEVHLEI-----KDATWIVKQPEYAVVQR 553 Query: 412 KSMAVFPCTAIC--TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469 SM F C T + W + L + R V D LV+ D+ DSGTYTCVA Sbjct: 554 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH-LVVADVSDDDSGTYTCVA 612 Query: 470 SSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWS---Q 526 ++ +DS + V +P PP + D SV LSW+ Sbjct: 613 NT-----------TLDS-----VSASAVLSVVDVPNPPFDLELTDQLDKSVQLSWTPGDD 656 Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFI 586 NN + I+ Y+ + + L + T + QT +K L P + Y F Sbjct: 657 NNSPITKFIIEYE-DAMHKPGLWHHQTEVSGT----------QTTAQLK-LSPYVNYSFR 704 Query: 587 VRTENSHGLSGPSPVSD 603 V NS G S PS S+ Sbjct: 705 VMAVNSIGKSLPSEASE 721 Score = 109 bits (263), Expect = 3e-22 Identities = 92/292 (31%), Positives = 132/292 (45%), Gaps = 21/292 (7%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSDTHRSILPAGGLF 67 APY I P ++ ++ + TL CRA G+P P I W GV + D R I G Sbjct: 354 APYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKI--DGDTI 411 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR-LEPESK--QSAQGDT 124 R + VY C A+N YG A V VL E R L P + Q Sbjct: 412 IFSNVQER---SSAVYQCNASNEYGYLL---ANAFVNVLAEPPRILTPANTLYQVIANRP 465 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 +L+C GSP P + W K + D + L + G L I A++ G Y C+ARN Sbjct: 466 ALLDC-AFFGSPLPTIEWFKGAKGSALHEDIYV-LHENGTLEIPVAQKDSTGTYTCVARN 523 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD--VLWRRSAGGG 242 G ++ + L+I +++ PE V Q GS V+F+C+V D VLW + Sbjct: 524 KLGMAKNEV-HLEIKDATWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKD--NR 580 Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294 +P +D L + +V D G Y+C A ++ +VSAS L+V D P+ Sbjct: 581 ELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPN 632 Score = 87.0 bits (206), Expect = 3e-15 Identities = 73/289 (25%), Positives = 121/289 (41%), Gaps = 14/289 (4%) Query: 30 TLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88 +L C A G P+P I W K G+L + T L+ H +D+G Y C A Sbjct: 283 SLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT----LQIIHVS-EADSGNYQCIAK 337 Query: 89 NSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147 N+ G T+ V V + + P++ + G+ L C G+P+P + W NG Sbjct: 338 NALGAIHH---TISVRVKAAPYWITAPQNLVLSPGEDGTLICRA-NGNPKPRISWLTNGV 393 Query: 148 TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG 207 + D +DG ++ + ++ + YQC A N G A A + + +P I Sbjct: 394 PIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYL-LANAFVNVLAEPPRILT 452 Query: 208 PEDVVAQTGSS--VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA 265 P + + Q ++ C G PLP + W + A G + + ++G+L + Sbjct: 453 PANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKD 512 Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314 G Y+C A N +G +L + D I P V+ G++ F C Sbjct: 513 STGTYTCVARNKLGMAKNEVHLEIKDATWIVKQPEYAVVQRGSMVSFEC 561 Score = 68.1 bits (159), Expect = 1e-09 Identities = 52/181 (28%), Positives = 79/181 (43%), Gaps = 10/181 (5%) Query: 10 EAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGL 66 + P I +Q P D + + + C A G P P+ W + G + D ++ P G Sbjct: 38 QPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGT 97 Query: 67 FFLRA-THGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGD 123 + + G+ + GVY C A N G A S N + + L + +LEP + QS G Sbjct: 98 LIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQS--GQ 155 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIA 182 ++VL C PP G P P ++W N L + R+ G+L + D Y C A Sbjct: 156 SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSE-RVSQGLNGDLYFSNVLPEDTREDYICYA 214 Query: 183 R 183 R Sbjct: 215 R 215 Score = 58.4 bits (135), Expect = 1e-06 Identities = 67/305 (21%), Positives = 116/305 (38%), Gaps = 30/305 (9%) Query: 200 IKPYLIT--GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257 ++P IT P+D + ++ QC G P P W R+ ++ + + G+ Sbjct: 37 VQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTG 96 Query: 258 RLDNVILAD------EGEYSCEAENSVGAVSASGYLT--VYDPPSINLSPNSVNVESGNV 309 L I+++ EG Y C A N GA ++ + P + ++SG Sbjct: 97 TLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQS 156 Query: 310 ARFTC-TATGRPEPTMFWSVEGNRTI-----IFPGMSRDKYHATAV-----FDGVTVLTI 358 C G P P +FW + + + G++ D Y + + D + Sbjct: 157 LVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARF 216 Query: 359 NDTDKNDSRNTIVCSAVNYAG-SSFVRGKLTVT------SDDDRPPPIIT--NGPSNQTL 409 N T + I ++ + + L+ T S +RPP +T SN+ Sbjct: 217 NHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEE 276 Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469 ++ C A P PII W E L +N + TL + + ++DSG Y C+A Sbjct: 277 LRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIA 336 Query: 470 SSRHG 474 + G Sbjct: 337 KNALG 341 Score = 54.4 bits (125), Expect = 2e-05 Identities = 56/218 (25%), Positives = 90/218 (41%), Gaps = 12/218 (5%) Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVI----QDARQTDAGR 177 + +V++C +G P P+ W +NG D D + + G G L+I + +T G Sbjct: 56 ENIVIQC-EAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGV 114 Query: 178 YQCIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLW 235 YQC ARN G S ++ P + E + Q+G S+ CR G P P + W Sbjct: 115 YQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFW 174 Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGE-YSCEAE-NSVGAVSASGYLTVYDPP 293 ++ RV +G L NV+ D E Y C A N + ++V Sbjct: 175 MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISV-KVI 233 Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGN 331 S++ +++ + F + R P F + EGN Sbjct: 234 SVDELNDTIAANLSD-TEFYGAKSSRERPPTFLTPEGN 270 Score = 37.9 bits (84), Expect = 1.7 Identities = 47/192 (24%), Positives = 71/192 (36%), Gaps = 12/192 (6%) Query: 287 LTVYDPPSINL-SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345 L + PP+I SP ++ C A G+P P+ W+ G I +D Sbjct: 34 LDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDI----DKDPLV 89 Query: 346 ATAVFDGVTVLTINDTDKNDSRNTIV-CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404 G ++ I K ++ + C+A N G++ V + V R P Sbjct: 90 TMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAA-VSNNIVVR--PSRSPLWTKEKL 146 Query: 405 SNQTLPIKSMAVFPC-TAICTPEPIIAWYFEG-EALIQNHRRNVTNDGTLVLKDLDKSDS 462 TL V PC I P PII W + L Q+ R + +G L ++ D+ Sbjct: 147 EPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDT 206 Query: 463 -GTYTCVASSRH 473 Y C A H Sbjct: 207 REDYICYARFNH 218 >UniRef50_Q4S5S6 Cluster: Chromosome 9 SCAF14729, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 9 SCAF14729, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1238 Score = 116 bits (279), Expect = 4e-24 Identities = 83/286 (29%), Positives = 130/286 (45%), Gaps = 12/286 (4%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 AP+ +E+P D+ +A + L CR+ G+P P + W+ G + T + + G + Sbjct: 338 APFWLEKPADLVLAPEEDGRLVCRSDGAPRPTVTWFINGEPIDPSTLQPNVEVSGETVVL 397 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL---EPESKQSAQGDTVVL 127 T +++ VY C A+N YG A V VL R+ E + +G L Sbjct: 398 RTVTTLNN--AVYQCNASNPYGYLL---ANAFVNVLHATPRILGSRNEYLKVIEGSRAFL 452 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 +C GSP P + W K GQ L R H G L I++ + D G Y C+ N AG Sbjct: 453 DCRY-FGSPVPELRWSKYGQGSLEGNRFRTH--SNGTLEIKNIQVVDQGAYLCVVSNVAG 509 Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247 E+ + +++ ++T P D+ G+ V F+C V D V G + LG Sbjct: 510 RDENQVR-IEVKEPTLIVTRPTDMKVIRGADVRFECAVKTDATTPVTTTWMKGTKPVTLG 568 Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293 +D+ +L + N+ AD G Y+C ++ + SAS L V D P Sbjct: 569 WRISMDESNLVISNINTADGGNYTCLVKSELEQKSASARLMVMDRP 614 Score = 91.9 bits (218), Expect = 1e-16 Identities = 85/308 (27%), Positives = 124/308 (40%), Gaps = 13/308 (4%) Query: 31 LNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89 L C A G P+P I W K G LVV RS + A + DAG Y C ATN Sbjct: 267 LECIAAGVPTPHITWRKDGEDLVV----RSPVKAKNFNKMIQIPRASFEDAGEYVCTATN 322 Query: 90 SYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148 + T+ V V F LE P A + L C G+P P V W NG+ Sbjct: 323 KLDYIQH---TITVQVKAAPFWLEKPADLVLAPEEDGRLVCRSD-GAPRPTVTWFINGEP 378 Query: 149 LLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI-TG 207 + V G +V++ + YQC A N G + +H P ++ + Sbjct: 379 IDPSTLQPNVEVSGETVVLRTVTTLNNAVYQCNASNPYGYLLANAFVNVLHATPRILGSR 438 Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267 E + GS CR G P+P++ W + G G++ R + +G+L + N+ + D+ Sbjct: 439 NEYLKVIEGSRAFLDCRYFGSPVPELRWSK-YGQGSLEGNRFRTHSNGTLEIKNIQVVDQ 497 Query: 268 GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA-TGRPEPTMFW 326 G Y C N G + V +P I P + V G RF C T P Sbjct: 498 GAYLCVVSNVAGRDENQVRIEVKEPTLIVTRPTDMKVIRGADVRFECAVKTDATTPVTTT 557 Query: 327 SVEGNRTI 334 ++G + + Sbjct: 558 WMKGTKPV 565 Score = 89.4 bits (212), Expect = 5e-16 Identities = 90/376 (23%), Positives = 158/376 (42%), Gaps = 27/376 (7%) Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT--DAGRYQ 179 G+ ++LEC+ G P P++ W+K+G+ L+ + N +IQ R + DAG Y Sbjct: 262 GEELLLECIAA-GVPTPHITWRKDGEDLVVRSPVK---AKNFNKMIQIPRASFEDAGEYV 317 Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239 C A N + I T+++ P+ + P D+V CR G P P V W + Sbjct: 318 CTATNKLDYIQHTI-TVQVKAAPFWLEKPADLVLAPEEDGRLVCRSDGAPRPTVTWFING 376 Query: 240 GGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV-YDPPSINL 297 + + V G ++ L V + Y C A N G + A+ ++ V + P I Sbjct: 377 EPIDPSTLQPNVEVSGETVVLRTVTTLNNAVYQCNASNPYGYLLANAFVNVLHATPRILG 436 Query: 298 SPNS-VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356 S N + V G+ A C G P P + WS G ++ G +R + H+ + + Sbjct: 437 SRNEYLKVIEGSRAFLDCRYFGSPVPELRWSKYGQGSL--EG-NRFRTHSNGTLEIKNIQ 493 Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416 ++ + +C N AG + ++ V + P +I P++ + + Sbjct: 494 VVD-------QGAYLCVVSNVAGRDENQVRIEV-----KEPTLIVTRPTDMKVIRGADVR 541 Query: 417 FPCTAIC-TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 F C P+ + +G + R ++ LV+ +++ +D G YTC+ S + Sbjct: 542 FECAVKTDATTPVTTTWMKGTKPVTLGWRISMDESNLVISNINTADGGNYTCLVKSELEQ 601 Query: 476 YVWSGALLV-DSPINP 490 S L+V D P P Sbjct: 602 KSASARLMVMDRPDPP 617 Score = 74.9 bits (176), Expect = 1e-11 Identities = 76/319 (23%), Positives = 125/319 (39%), Gaps = 22/319 (6%) Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEA 274 G + +C G P P + WR+ G + VK + + +++ D GEY C A Sbjct: 262 GEELLLECIAAGVPTPHITWRKD-GEDLVVRSPVKAKNFNKMIQIPRASFEDAGEYVCTA 320 Query: 275 ENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334 N + + + + V P P + + R C + G P PT+ W + G Sbjct: 321 TNKLDYIQHTITVQVKAAPFWLEKPADLVLAPEEDGRLVCRSDGAPRPTVTWFINGEP-- 378 Query: 335 IFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394 I P + + G TV+ T N++ C+A N G + V Sbjct: 379 IDPSTLQPNVEVS----GETVVLRTVTTLNNA--VYQCNASNPYGYLLANAFVNVLH--- 429 Query: 395 RPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTL 452 P I+ G N+ L + S A C +P P + W G+ ++ +R ++GTL Sbjct: 430 ATPRIL--GSRNEYLKVIEGSRAFLDCRYFGSPVPELRWSKYGQGSLEGNRFRTHSNGTL 487 Query: 453 VLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPIT 512 +K++ D G Y CV S+ G+ + V P + R D+ + G + Sbjct: 488 EIKNIQVVDQGAYLCVVSNVAGRDENQVRIEVK---EPTLIVTRPTDMKVIRGADVRFEC 544 Query: 513 HNVTD--TSVTLSWSQNNK 529 TD T VT +W + K Sbjct: 545 AVKTDATTPVTTTWMKGTK 563 Score = 55.6 bits (128), Expect = 8e-06 Identities = 41/144 (28%), Positives = 62/144 (43%), Gaps = 4/144 (2%) Query: 10 EAPYIIEQPLDVTVARHQPA-TLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGL 66 + P II+Q + + + A + C A G+P P W + G V D S+ G Sbjct: 1 QPPTIIKQSMKEHIVDAKDAMVIECEAKGNPHPIFSWRRNGRYYNVARDPQASMRRHSGT 60 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126 + A + +A Y C A+N YG+A S L + R E + G +V Sbjct: 61 LDIYARNNPEQYEAE-YQCVASNMYGSAYSNKIRLRLYRAPVWPREIIEPVVISAGLPLV 119 Query: 127 LECLPPRGSPEPNVYWKKNGQTLL 150 L C PP G P+P YW + + +L Sbjct: 120 LSCDPPPGPPKPETYWMSSCECVL 143 Score = 42.3 bits (95), Expect = 0.078 Identities = 32/121 (26%), Positives = 54/121 (44%), Gaps = 6/121 (4%) Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQ--TLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQ 179 D +V+EC +G+P P W++NG+ + D + M G ++ ++ + YQ Sbjct: 19 DAMVIEC-EAKGNPHPIFSWRRNGRYYNVARDPQASMRRHSGTLDIYARNNPEQYEAEYQ 77 Query: 180 CIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQC-RVGGDPLPDVLWRR 237 C+A N G+ S L+++ P + E VV G + C G P P+ W Sbjct: 78 CVASNMYGSAYSNKIRLRLYRAPVWPREIIEPVVISAGLPLVLSCDPPPGPPKPETYWMS 137 Query: 238 S 238 S Sbjct: 138 S 138 Score = 41.9 bits (94), Expect = 0.10 Identities = 56/257 (21%), Positives = 96/257 (37%), Gaps = 20/257 (7%) Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 S +S V G C A G P P + W +G ++ + ++ ++ Sbjct: 253 SSSSTLVLLGEELLLECIAAGVPTPHITWRKDGEDLVVRSPVKAKNFN--------KMIQ 304 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417 I D+ VC+A N +++ +TV + P P++ L + Sbjct: 305 IPRASFEDA-GEYVCTATNKL--DYIQHTITV---QVKAAPFWLEKPADLVLAPEEDGRL 358 Query: 418 PCTAICTPEPIIAWYFEGEALIQNH-RRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGK 475 C + P P + W+ GE + + + NV G T+VL+ + ++ Y C AS+ +G Sbjct: 359 VCRSDGAPRPTVTWFINGEPIDPSTLQPNVEVSGETVVLRTVTTLNNAVYQCNASNPYG- 417 Query: 476 YVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSI 535 Y+ + A + P I R + + G L WS K G S+ Sbjct: 418 YLLANAFVNVLHATPRILGSRNEYLKVIEGSRAFLDCRYFGSPVPELRWS---KYGQGSL 474 Query: 536 LGYQVEVFSRETLSGNN 552 G + S TL N Sbjct: 475 EGNRFRTHSNGTLEIKN 491 >UniRef50_A7SVH4 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 412 Score = 116 bits (279), Expect = 4e-24 Identities = 108/418 (25%), Positives = 176/418 (42%), Gaps = 49/418 (11%) Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSP 136 +DAG Y C A N+ G ++ V F+ + + + +G + L C G P Sbjct: 12 TDAGRYVCTAVNAIGIIH-KSTNYIVWYENRPFKTKIGNNLTTMKGRKLTLIC-HATGRP 69 Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196 P + W + G+ + R + + G+L+++ +D GRY C ARNA G + T+ Sbjct: 70 RPTITWFRGGEEM------RTKVTNNGSLILEKVSSSDIGRYTCTARNAFGKDNANSTTI 123 Query: 197 KIHI-KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL-DD 254 P ++ +++ T + + C V G P P V+W + G + +G V+ D+ Sbjct: 124 PPGDGSPVKVSVGDNITVITDTPLLIDCEVSGIPFPSVVWVKD---GRVLMGEGYVIFDN 180 Query: 255 GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP------------PSINLSPNSV 302 G+L L AD G Y+C A NS G S T+ P P+I ++ Sbjct: 181 GTLVLRRARPADSGRYTCTANNSRGKDHISSQPTIERPVAPRDIPLGDGSPTIARIADNA 240 Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362 V +G+ C ATG P+P++ W +G R +I G + + + V Sbjct: 241 TVLTGSRLTIDCVATGVPKPSIIWRKDG-RELIGAGSYMAPGNGSLLIQQVAA------- 292 Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD-----DRPPPIITNGPSNQTLPIKSMAVF 417 C+A N G V + V + D D P + G +L + + Sbjct: 293 --SHHGVFTCTATNPVGEDSVSSNIRVRTTDKVEKSDMKPVDVRIGGQVTSLSGVDITL- 349 Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 C+A P P I W G+ + R LVL+++ SDSG YTC+AS+ G+ Sbjct: 350 NCSARGLPPPDIEWMNGGKMITVQGPR-------LVLRNVMSSDSGNYTCIASNVVGR 400 Score = 116 bits (279), Expect = 4e-24 Identities = 97/361 (26%), Positives = 154/361 (42%), Gaps = 40/361 (11%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 ++T + + TL C A G P P I W++GG + + G L + + SD Sbjct: 50 NLTTMKGRKLTLICHATGRPRPTITWFRGG----EEMRTKVTNNGSLILEKVSS----SD 101 Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139 G Y C A N++G + + T+ ++ + DT +L G P P+ Sbjct: 102 IGRYTCTARNAFGKDNANSTTIPPGD-GSPVKVSVGDNITVITDTPLLIDCEVSGIPFPS 160 Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG--------TRES 191 V W K+G+ L+ +G + D G LV++ AR D+GRY C A N+ G T E Sbjct: 161 VVWVKDGRVLMGEG---YVIFDNGTLVLRRARPADSGRYTCTANNSRGKDHISSQPTIER 217 Query: 192 AIATLKIHI---KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248 +A I + P + ++ TGS +T C G P P ++WR+ G + G Sbjct: 218 PVAPRDIPLGDGSPTIARIADNATVLTGSRLTIDCVATGVPKPSIIWRKD-GRELIGAGS 276 Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI---NLSPNSVNVE 305 +GSL + V + G ++C A N VG S S + V + ++ P V + Sbjct: 277 YMAPGNGSLLIQQVAASHHGVFTCTATNPVGEDSVSSNIRVRTTDKVEKSDMKPVDVRIG 336 Query: 306 ------SGNVARFTCTATGRPEPTMFW-------SVEGNRTIIFPGMSRDKYHATAVFDG 352 SG C+A G P P + W +V+G R ++ MS D + T + Sbjct: 337 GQVTSLSGVDITLNCSARGLPPPDIEWMNGGKMITVQGPRLVLRNVMSSDSGNYTCIASN 396 Query: 353 V 353 V Sbjct: 397 V 397 Score = 104 bits (249), Expect = 2e-20 Identities = 90/323 (27%), Positives = 140/323 (43%), Gaps = 26/323 (8%) Query: 163 GNLVIQDARQTDAGRYQCIARNAAGT-RESAIATLKIHIKPYLITGPEDVVAQTGSSVTF 221 G L I R TDAGRY C A NA G +S + +P+ ++ G +T Sbjct: 2 GTLSIVLRRTTDAGRYVCTAVNAIGIIHKSTNYIVWYENRPFKTKIGNNLTTMKGRKLTL 61 Query: 222 QCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281 C G P P + W R GG M R KV ++GSL L+ V +D G Y+C A N+ G Sbjct: 62 ICHATGRPRPTITWFR--GGEEM---RTKVTNNGSLILEKVSSSDIGRYTCTARNAFGKD 116 Query: 282 SA-SGYLTVYDPPSINLSP-NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGM 339 +A S + D + +S +++ V + C +G P P++ W +G R ++ G Sbjct: 117 NANSTTIPPGDGSPVKVSVGDNITVITDTPLLIDCEVSGIPFPSVVWVKDG-RVLMGEGY 175 Query: 340 SRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV---TSDDDRP 396 +FD T++ + R T C+A N G + + T+ + D P Sbjct: 176 --------VIFDNGTLVLRRARPADSGRYT--CTANNSRGKDHISSQPTIERPVAPRDIP 225 Query: 397 ----PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTL 452 P I N T+ S C A P+P I W +G LI +G+L Sbjct: 226 LGDGSPTIARIADNATVLTGSRLTIDCVATGVPKPSIIWRKDGRELIGAGSYMAPGNGSL 285 Query: 453 VLKDLDKSDSGTYTCVASSRHGK 475 +++ + S G +TC A++ G+ Sbjct: 286 LIQQVAASHHGVFTCTATNPVGE 308 Score = 93.1 bits (221), Expect = 4e-17 Identities = 78/290 (26%), Positives = 129/290 (44%), Gaps = 38/290 (13%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 ++TV P ++C G P P++ W K G +++ + + I G L RA +D Sbjct: 138 NITVITDTPLLIDCEVSGIPFPSVVWVKDGRVLMGEGY-VIFDNGTLVLRRARP----AD 192 Query: 80 AGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESKQSAQ---------GDTVVLEC 129 +G Y C A NS G S T+ V + L S A+ G + ++C Sbjct: 193 SGRYTCTANNSRGKDHISSQPTIERPVAPRDIPLGDGSPTIARIADNATVLTGSRLTIDC 252 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGT 188 + G P+P++ W+K+G+ L+ G ++ G G+L+IQ + G + C A N G Sbjct: 253 VAT-GVPKPSIIWRKDGRELIGAGS---YMAPGNGSLLIQQVAASHHGVFTCTATNPVG- 307 Query: 189 RESAIATLKIH---------IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239 +S + +++ +KP + V + +G +T C G P PD+ W Sbjct: 308 EDSVSSNIRVRTTDKVEKSDMKPVDVRIGGQVTSLSGVDITLNCSARGLPPPDIEWMNG- 366 Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 G++ + L L NV+ +D G Y+C A N VG SAS + V Sbjct: 367 -------GKMITVQGPRLVLRNVMSSDSGNYTCIASNVVGRASASTMVNV 409 Score = 69.7 bits (163), Expect = 4e-10 Identities = 60/227 (26%), Positives = 93/227 (40%), Gaps = 20/227 (8%) Query: 266 DEGEYSCEAENSVGAVSAS-GYLTVYDP-PSINLSPNSVNVESGNVARFTCTATGRPEPT 323 D G Y C A N++G + S Y+ Y+ P N++ G C ATGRP PT Sbjct: 13 DAGRYVCTAVNAIGIIHKSTNYIVWYENRPFKTKIGNNLTTMKGRKLTLICHATGRPRPT 72 Query: 324 MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383 + W G T V + +++ + + R T C+A N G Sbjct: 73 ITWFRGGEEM------------RTKVTNNGSLILEKVSSSDIGRYT--CTARNAFGKD-- 116 Query: 384 RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR 443 T D P ++ G N T+ + + C P P + W +G L+ Sbjct: 117 NANSTTIPPGDGSPVKVSVG-DNITVITDTPLLIDCEVSGIPFPSVVWVKDGRVLM-GEG 174 Query: 444 RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490 + ++GTLVL+ +DSG YTC A++ GK S ++ P+ P Sbjct: 175 YVIFDNGTLVLRRARPADSGRYTCTANNSRGKDHISSQPTIERPVAP 221 Score = 62.9 bits (146), Expect = 5e-08 Identities = 54/195 (27%), Positives = 82/195 (42%), Gaps = 22/195 (11%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 +P I + TV T++C A G P P+I W K G ++ + P G ++ Sbjct: 230 SPTIARIADNATVLTGSRLTIDCVATGVPKPSIIWRKDGRELIG-AGSYMAPGNGSLLIQ 288 Query: 71 ATHGRVHSDAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQ------SAQGD 123 H GV+ C ATN G + S N + E+ ++P + S G Sbjct: 289 QVAASHH---GVFTCTATNPVGEDSVSSNIRVRTTDKVEKSDMKPVDVRIGGQVTSLSGV 345 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183 + L C RG P P++ W G +M V G LV+++ +D+G Y CIA Sbjct: 346 DITLNC-SARGLPPPDIEWMNGG---------KMITVQGPRLVLRNVMSSDSGNYTCIAS 395 Query: 184 NAAGTRESAIATLKI 198 N G R SA + + Sbjct: 396 NVVG-RASASTMVNV 409 >UniRef50_UPI0000D57760 Cluster: PREDICTED: similar to leucine-rich repeats and immunoglobulin-like domains 2; n=1; Tribolium castaneum|Rep: PREDICTED: similar to leucine-rich repeats and immunoglobulin-like domains 2 - Tribolium castaneum Length = 756 Score = 116 bits (278), Expect = 5e-24 Identities = 68/230 (29%), Positives = 109/230 (47%), Gaps = 13/230 (5%) Query: 113 EPESKQSA-QGDTVVLECLPPRGSPEPNVY-WKKNGQTLLFDGDSRMHLVDG------GN 164 EPE + A +G+ + L C S P + WKK+ ++ + DG Sbjct: 321 EPEPEIMALKGENITLSCTAMSSSNSPMTFQWKKDNVDIINMNINENSSSDGKTTEAVSK 380 Query: 165 LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR 224 L I + ++AG+YQC+ N GT S +++ + I P + P++V + G C Sbjct: 381 LNIYRVQHSNAGKYQCVVSNIFGTTYSQKSSISVLIFPTFLKRPDNVTVKAGDVAKLVCA 440 Query: 225 VGGDPLPDVLWRRSAGGGNMPLGRVKVLD----DGSLRLDNVILADEGEYSCEAENSVGA 280 G+P P++ W++ GG + P R + + D S + NV D G YSC A N+ G Sbjct: 441 AHGEPQPEIAWQKD-GGNDFPAARERRMHVLPADDSFFISNVKPTDMGIYSCTAHNAAGT 499 Query: 281 VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330 + + LTVY+ PS S + V +G + C A+G P+PT+ W G Sbjct: 500 IVTNASLTVYEKPSFVKSMENKEVTAGELVVLQCMASGTPKPTITWYKNG 549 Score = 105 bits (252), Expect = 7e-21 Identities = 74/287 (25%), Positives = 127/287 (44%), Gaps = 12/287 (4%) Query: 12 PYIIEQPL-DVTVARHQPATLNCRA-GGSPSP-AIRWYKGGVLVVSDTHRSILPAGGLFF 68 P + E+P ++ + + TL+C A S SP +W K V +++ + G Sbjct: 316 PRLTEEPEPEIMALKGENITLSCTAMSSSNSPMTFQWKKDNVDIINMNINENSSSDGKTT 375 Query: 69 LRATHGRV----HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124 + + HS+AG Y C +N +GT S+ +++ V + F P++ GD Sbjct: 376 EAVSKLNIYRVQHSNAGKYQCVVSNIFGTTYSQKSSISVLIF-PTFLKRPDNVTVKAGDV 434 Query: 125 VVLECLPPRGSPEPNVYWKKN-GQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIA 182 L C G P+P + W+K+ G + RMH++ + I + + TD G Y C A Sbjct: 435 AKLVC-AAHGEPQPEIAWQKDGGNDFPAARERRMHVLPADDSFFISNVKPTDMGIYSCTA 493 Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242 NAAGT + A+L ++ KP + E+ G V QC G P P + W ++ Sbjct: 494 HNAAGTIVTN-ASLTVYEKPSFVKSMENKEVTAGELVVLQCMASGTPKPTITWYKNGEPI 552 Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 ++ + + + + +D G+Y C NS+G + L V Sbjct: 553 RATERHFFTAEEQLMIIVDTVQSDSGKYECHLNNSLGEKTGYSLLRV 599 Score = 92.7 bits (220), Expect = 6e-17 Identities = 73/287 (25%), Positives = 116/287 (40%), Gaps = 23/287 (8%) Query: 201 KPYLITGPE-DVVAQTGSSVTFQCRV---GGDPLPDVLWRRSAGGGNMPLGRVKVLDD-- 254 KP L PE +++A G ++T C P+ + + NM + D Sbjct: 315 KPRLTEEPEPEIMALKGENITLSCTAMSSSNSPMTFQWKKDNVDIINMNINENSSSDGKT 374 Query: 255 ----GSLRLDNVILADEGEYSCEAENSVGAV-SASGYLTVYDPPSINLSPNSVNVESGNV 309 L + V ++ G+Y C N G S ++V P+ P++V V++G+V Sbjct: 375 TEAVSKLNIYRVQHSNAGKYQCVVSNIFGTTYSQKSSISVLIFPTFLKRPDNVTVKAGDV 434 Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369 A+ C A G P+P + W +G FP + H D + + TD Sbjct: 435 AKLVCAAHGEPQPEIAWQKDGGND--FPAARERRMHVLPADDSFFISNVKPTDMG----I 488 Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429 C+A N AG+ LTV P N+ + + V C A TP+P I Sbjct: 489 YSCTAHNAAGTIVTNASLTVYEK-----PSFVKSMENKEVTAGELVVLQCMASGTPKPTI 543 Query: 430 AWYFEGEALIQNHRRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGK 475 WY GE + R T + +++ D +SDSG Y C ++ G+ Sbjct: 544 TWYKNGEPIRATERHFFTAEEQLMIIVDTVQSDSGKYECHLNNSLGE 590 Score = 43.6 bits (98), Expect = 0.034 Identities = 26/87 (29%), Positives = 36/87 (41%), Gaps = 3/87 (3%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 +T E P ++ + V + L C A G+P P I WYK G + + Sbjct: 506 LTVYEKPSFVKSMENKEVTAGELVVLQCMASGTPKPTITWYKNGEPIRATERHFFTAEEQ 565 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYG 92 L + T V SD+G Y C NS G Sbjct: 566 LMIIVDT---VQSDSGKYECHLNNSLG 589 Score = 39.5 bits (88), Expect = 0.55 Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 4/91 (4%) Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG----EALIQNHRRNVTNDGTLV 453 P P N T+ +A C A P+P IAW +G A + + D + Sbjct: 418 PTFLKRPDNVTVKAGDVAKLVCAAHGEPQPEIAWQKDGGNDFPAARERRMHVLPADDSFF 477 Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 + ++ +D G Y+C A + G V + +L V Sbjct: 478 ISNVKPTDMGIYSCTAHNAAGTIVTNASLTV 508 >UniRef50_O44329 Cluster: Receptor tyrosine phosphatase; n=1; Hirudo medicinalis|Rep: Receptor tyrosine phosphatase - Hirudo medicinalis (Medicinal leech) Length = 1437 Score = 116 bits (278), Expect = 5e-24 Identities = 91/304 (29%), Positives = 142/304 (46%), Gaps = 29/304 (9%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD---THRSILP 62 V +AP I P D V + A+ C+A G+P+P + W +G + D T S +P Sbjct: 29 VDHDDAPRITTAPRDQKVMEGKIASFFCKASGNPAPEVYWKRGWKESLHDKNETKTSNMP 88 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYG-TARSRNATLHVAVLREEFR-----LE-PE 115 G + LR + D + C A + G A + A LH+ EE + LE PE Sbjct: 89 HGSV--LRVDPTKWQKDETIIECVAESGIGHQAATATARLHIYRENEEPKGFPRLLETPE 146 Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175 + + +L+C G PEP+VYW K+ + D R+ ++ GG+L I++ + +D Sbjct: 147 MRSVEKDRNFILKC-SATGDPEPSVYWLKDNIPVDM-SDKRIQVLPGGSLSIRNGQGSDE 204 Query: 176 GRYQCIARNAAGTRESAIATLKIHIK---PYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232 G+Y+C+A N GT S A+L I I+ P+ ++ G S+ C VGG P+P Sbjct: 205 GKYECVAENIHGTVHSFPASLYIRIRRVPPHFSVQIQNKEVPLGGSLNVTCVVGGAPMPH 264 Query: 233 VLWRRS----AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288 V W+ N+P+G+ LRL++V G Y C + +G V +T Sbjct: 265 VRWKHGDIDLTPENNIPIGK------NVLRLEDV--KQSGTYKCIGSSELGNVEQEINVT 316 Query: 289 VYDP 292 V P Sbjct: 317 VVVP 320 Score = 87.8 bits (208), Expect = 2e-15 Identities = 66/229 (28%), Positives = 103/229 (44%), Gaps = 18/229 (7%) Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFD-GDSRMHLVDGGNLVIQDAR- 171 P ++ +G C G+P P VYWK+ + L D +++ + G+++ D Sbjct: 41 PRDQKVMEGKIASFFC-KASGNPAPEVYWKRGWKESLHDKNETKTSNMPHGSVLRVDPTK 99 Query: 172 -QTDAGRYQCIARNAAGTRESAIATLKIHIK---------PYLITGPEDVVAQTGSSVTF 221 Q D +C+A + G ++A AT ++HI P L+ PE + + Sbjct: 100 WQKDETIIECVAESGIG-HQAATATARLHIYRENEEPKGFPRLLETPEMRSVEKDRNFIL 158 Query: 222 QCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281 +C GDP P V W + +M R++VL GSL + N +DEG+Y C AEN G V Sbjct: 159 KCSATGDPEPSVYWLKDNIPVDMSDKRIQVLPGGSLSIRNGQGSDEGKYECVAENIHGTV 218 Query: 282 ---SASGYLTVYD-PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326 AS Y+ + PP ++ + V G TC G P P + W Sbjct: 219 HSFPASLYIRIRRVPPHFSVQIQNKEVPLGGSLNVTCVVGGAPMPHVRW 267 Score = 69.3 bits (162), Expect = 6e-10 Identities = 75/286 (26%), Positives = 114/286 (39%), Gaps = 26/286 (9%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDGS-LR 258 P + T P D G +F C+ G+P P+V W+R K + GS LR Sbjct: 35 PRITTAPRDQKVMEGKIASFFCKASGNPAPEVYWKRGWKESLHDKNETKTSNMPHGSVLR 94 Query: 259 LD-NVILADEGEYSCEAENSVG--AVSASGYLTVY----DP---PSINLSPNSVNVESGN 308 +D DE C AE+ +G A +A+ L +Y +P P + +P +VE Sbjct: 95 VDPTKWQKDETIIECVAESGIGHQAATATARLHIYRENEEPKGFPRLLETPEMRSVEKDR 154 Query: 309 VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368 C+ATG PEP+++W + P DK V G ++ N ++ + Sbjct: 155 NFILKCSATGDPEPSVYWLKDN-----IPVDMSDK--RIQVLPGGSLSIRNGQGSDEGKY 207 Query: 369 TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428 V ++ SF ++ R PP + N+ +P+ C P P Sbjct: 208 ECVAENIHGTVHSF---PASLYIRIRRVPPHFSVQIQNKEVPLGGSLNVTCVVGGAPMPH 264 Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 + W G+ I N G VL+ D SGTY C+ SS G Sbjct: 265 VRWK-HGD--IDLTPENNIPIGKNVLRLEDVKQSGTYKCIGSSELG 307 Score = 65.7 bits (153), Expect = 7e-09 Identities = 47/190 (24%), Positives = 82/190 (43%), Gaps = 12/190 (6%) Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHA-TAV 349 D P I +P V G +A F C A+G P P ++W ++ DK T+ Sbjct: 33 DAPRITTAPRDQKVMEGKIASFFCKASGNPAPEVYWKRGWKESL------HDKNETKTSN 86 Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAG--SSFVRGKLTVTSDDDRPP--PIITNGPS 405 +VL ++ T I C A + G ++ +L + +++ P P + P Sbjct: 87 MPHGSVLRVDPTKWQKDETIIECVAESGIGHQAATATARLHIYRENEEPKGFPRLLETPE 146 Query: 406 NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKDLDKSDSGT 464 +++ + C+A PEP + W + + + +R V G+L +++ SD G Sbjct: 147 MRSVEKDRNFILKCSATGDPEPSVYWLKDNIPVDMSDKRIQVLPGGSLSIRNGQGSDEGK 206 Query: 465 YTCVASSRHG 474 Y CVA + HG Sbjct: 207 YECVAENIHG 216 Score = 44.0 bits (99), Expect = 0.025 Identities = 34/100 (34%), Positives = 50/100 (50%), Gaps = 7/100 (7%) Query: 730 VPDGPPINIEM--FILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINT 787 VP G P NI + F + T+ L+W+ P+++++ G T Y VV + L NK + N Sbjct: 319 VPAGAPQNITIHPFGSSATSAKLQWNAPDIRIKQGDSTLYEVVYH-LRQDQNKEW-STNI 376 Query: 788 TVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYF 827 T +I NL Y QI A T G GP+S ++ F Sbjct: 377 T---EEFIIFENLLPNSEYIFQIRAHTYKGPGPWSYQLPF 413 >UniRef50_P16621 Cluster: Tyrosine-protein phosphatase Lar precursor; n=37; cellular organisms|Rep: Tyrosine-protein phosphatase Lar precursor - Drosophila melanogaster (Fruit fly) Length = 2029 Score = 116 bits (278), Expect = 5e-24 Identities = 90/305 (29%), Positives = 142/305 (46%), Gaps = 27/305 (8%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPA- 63 V + P II +P + V A+ C A G P P+I W K G V R ++L Sbjct: 30 VDAAHPPEIIRKPQNQGVRVGGVASFYCAARGDPPPSIVWRKNGKKVSGTQSRYTVLEQP 89 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE------FRLEPESK 117 GG+ LR R D Y C A N G A S +ATL + + P ++ Sbjct: 90 GGISILRIEPVRAGRDDAPYECVAENGVGDAVSADATLTIYEGDKTPAGFPVITQGPGTR 149 Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR 177 G TV++ C G+P PN+YW KN QT + + R L DG L I+++R+ D G+ Sbjct: 150 VIEVGHTVLMTC-KAIGNPTPNIYWIKN-QTKVDMSNPRYSLKDGF-LQIENSREEDQGK 206 Query: 178 YQCIARNAAGTRESAIATLKIHIK--PYLITGPEDVVAQT--GSSVTFQCRVGGDPLPDV 233 Y+C+A N+ GT S L + ++ P + P + +++ GS++ C G P+P V Sbjct: 207 YECVAENSMGTEHSKATNLYVKVRRVPPTFSRPPETISEVMLGSNLNLSCIAVGSPMPHV 266 Query: 234 LWRRSAGG----GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 W + + MP+GR L+L N+ + Y+C A +++G + + + V Sbjct: 267 KWMKGSEDLTPENEMPIGR------NVLQLINI--QESANYTCIAASTLGQIDSVSVVKV 318 Query: 290 YDPPS 294 P+ Sbjct: 319 QSLPT 323 Score = 111 bits (266), Expect = 1e-22 Identities = 151/636 (23%), Positives = 250/636 (39%), Gaps = 94/636 (14%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS----L 257 P +I P++ + G +F C GDP P ++WR++ + R VL+ L Sbjct: 36 PEIIRKPQNQGVRVGGVASFYCAARGDPPPSIVWRKNGKKVSGTQSRYTVLEQPGGISIL 95 Query: 258 RLDNVILA-DEGEYSCEAENSVG-AVSASGYLTVYDP-------PSINLSPNSVNVESGN 308 R++ V D+ Y C AEN VG AVSA LT+Y+ P I P + +E G+ Sbjct: 96 RIEPVRAGRDDAPYECVAENGVGDAVSADATLTIYEGDKTPAGFPVITQGPGTRVIEVGH 155 Query: 309 VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368 TC A G P P ++W N+T + MS +Y ++ DG + + + + + Sbjct: 156 TVLMTCKAIGNPTPNIYWIK--NQTKV--DMSNPRY---SLKDGFLQI---ENSREEDQG 205 Query: 369 TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN-QTLPIKSMAVFPCTAICTPEP 427 C A N G+ + + R PP + P + + S C A+ +P P Sbjct: 206 KYECVAENSMGTEHSKAT-NLYVKVRRVPPTFSRPPETISEVMLGSNLNLSCIAVGSPMP 264 Query: 428 IIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 + W E L + + G VL+ ++ +S YTC+A+S G+ +DS Sbjct: 265 HVKWMKGSEDLTPENEMPI---GRNVLQLINIQESANYTCIAASTLGQ--------IDS- 312 Query: 488 INPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRET 547 V SLP PT VT TSV L WS G + Y ++ Sbjct: 313 -------VSVVKVQSLPTAPTDVQISEVTATSVRLEWSYK---GPEDLQYYVIQY----- 357 Query: 548 LSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607 P+N+ + +YVV++L P Y F V N+ G GP + T Sbjct: 358 -----KPKNANQAFSEISGIITMYYVVRALSPYTEYEFYVIAVNNIG-RGPPSAPATCTT 411 Query: 608 GDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNF--YYLEGLF 665 G+ T + ++ RN ++ + S T+ + WE + G Sbjct: 412 GE--------TKMESAP--RN----------VQVRTLSSSTMVITWEPPETPNGQVTGYK 451 Query: 666 IYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFL--IPFYKKFEGKPSNSRV 723 +Y+ N + + +S V E+T++ + T + + + Y P ++ V Sbjct: 452 VYYTTNSN-----QPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAGPMSTPV 506 Query: 724 AQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMV 783 P N + T V L+W+ P +N I Y + W D AN+ Sbjct: 507 QVKAQQGVPSQPSNFRATDIGETAVTLQWTKPTHSSEN--IVHYELY--WNDTYANQ--- 559 Query: 784 AINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819 A + + + + + L Y + +AA + G G Sbjct: 560 AHHKRISNSEAYTLDGLYPDTLYYIWLAARSQRGEG 595 Score = 80.6 bits (190), Expect = 2e-13 Identities = 51/186 (27%), Positives = 76/186 (40%), Gaps = 7/186 (3%) Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 PP I P + V G VA F C A G P P++ W G + ++ +Y Sbjct: 35 PPEIIRKPQNQGVRVGGVASFYCAARGDPPPSIVWRKNGKKV----SGTQSRYTVLEQPG 90 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSF-VRGKLTVTSDDDRPP--PIITNGPSNQT 408 G+++L I C A N G + LT+ D P P+IT GP + Sbjct: 91 GISILRIEPVRAGRDDAPYECVAENGVGDAVSADATLTIYEGDKTPAGFPVITQGPGTRV 150 Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468 + + + C AI P P I W + ++ R DG L +++ + D G Y CV Sbjct: 151 IEVGHTVLMTCKAIGNPTPNIYWIKNQTKVDMSNPRYSLKDGFLQIENSREEDQGKYECV 210 Query: 469 ASSRHG 474 A + G Sbjct: 211 AENSMG 216 Score = 66.1 bits (154), Expect = 6e-09 Identities = 46/188 (24%), Positives = 90/188 (47%), Gaps = 10/188 (5%) Query: 639 IEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLR 698 ++ + + + +++L W L+ I ++P + E+ I+ + + +L Sbjct: 328 VQISEVTATSVRLEWSYKGPEDLQYYVIQYKPKNANQAFSEISGII----TMYYVVRALS 383 Query: 699 KYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQ 758 YT+YEF++I G PS T + + P N+++ L+++T+ + W PPE Sbjct: 384 PYTEYEFYVIAVNNIGRGPPSAPATCTTGETKMESAPRNVQVRTLSSSTMVITWEPPE-- 441 Query: 759 LQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSL-IMTNLTSGVSYSVQIAAETIIG 817 NG +TGY V + +N+ + N+ + + L ++ LT Y+V++ A T +G Sbjct: 442 TPNGQVTGYKV---YYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMG 498 Query: 818 LGPFSQKV 825 GP S V Sbjct: 499 AGPMSTPV 506 Score = 66.1 bits (154), Expect = 6e-09 Identities = 51/189 (26%), Positives = 87/189 (46%), Gaps = 4/189 (2%) Query: 639 IEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLD-NITIEYEMKTILHSNDVSGFEITSL 697 I A S TI L W G IY++ + E + T + N ++ + L Sbjct: 617 ITAIATSSTTISLSWLPPPVERSNGRIIYYKVFFVEVGREDDEATTMTLN-MTSIVLDEL 675 Query: 698 RKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPEL 757 +++T+Y+ +++ +G S+ + +T +DVP G P +++ LN+T++H+ W PP Sbjct: 676 KRWTEYKIWVLAGTSVGDGPRSHPIILRTQEDVP-GDPQDVKATPLNSTSIHVSWKPPLE 734 Query: 758 QLQNGIITGYNVVVNWL-DVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETII 816 + +NGII GY++ L D V +T L YS+Q+AA T Sbjct: 735 KDRNGIIRGYHIHAQELRDEGKGFLNEPFKFDVVDTLEFNVTGLQPDTKYSIQVAALTRK 794 Query: 817 GLGPFSQKV 825 G G S + Sbjct: 795 GDGDRSAAI 803 Score = 55.2 bits (127), Expect = 1e-05 Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 4/134 (2%) Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751 + + L T Y +L ++ EG + +T VP PP NI ++TT+ L Sbjct: 571 YTLDGLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQYVPGAPPRNITAIATSSTTISLS 630 Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811 W PP ++ NG I Y V V + T TS+++ L Y + + Sbjct: 631 WLPPPVERSNGRIIYYKVFF----VEVGREDDEATTMTLNMTSIVLDELKRWTEYKIWVL 686 Query: 812 AETIIGLGPFSQKV 825 A T +G GP S + Sbjct: 687 AGTSVGDGPRSHPI 700 Score = 53.6 bits (123), Expect = 3e-05 Identities = 34/105 (32%), Positives = 51/105 (48%), Gaps = 7/105 (6%) Query: 722 RVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVN-WLDVPANK 780 ++ QT + P GPP NI + + + W PP + +NGIIT Y+V + +D Sbjct: 900 KIFQTPEGTPGGPPSNITIRFQTPDVLCVTWDPPTREHRNGIITRYDVQFHKKIDHGLGS 959 Query: 781 SMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825 N T+ +A + TNL Y ++ A T G GPFS K+ Sbjct: 960 ER---NMTLRKA---VFTNLEENTEYIFRVRAYTKQGAGPFSDKL 998 Score = 45.6 bits (103), Expect = 0.008 Identities = 35/140 (25%), Positives = 61/140 (43%), Gaps = 7/140 (5%) Query: 688 DVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNT-T 746 D F +T L+ TKY + +K +G S + V +T VP P +++++ Sbjct: 769 DTLEFNVTGLQPDTKYSIQVAALTRKGDGDRSAAIVVKTPGGVPVRPTVSLKIMEREPIV 828 Query: 747 TVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSY 806 ++ L+W P G + GY + D + M++ Q T NL GV Y Sbjct: 829 SIELEWERPAQTY--GELRGYRLRWGVKDQALKEEMLS----GPQMTKKRFDNLERGVEY 882 Query: 807 SVQIAAETIIGLGPFSQKVY 826 ++A IG+G + K++ Sbjct: 883 EFRVAGSNHIGIGQETVKIF 902 Score = 41.5 bits (93), Expect = 0.14 Identities = 38/144 (26%), Positives = 60/144 (41%), Gaps = 6/144 (4%) Query: 695 TSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSP 754 T+L + T+Y F + + K+ G S+ + +T D+ P ++++ + T + W P Sbjct: 971 TNLEENTEYIFRVRAYTKQGAGPFSDKLIVETERDMGRAP-MSLQAEATSEQTAEIWWEP 1029 Query: 755 PELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAET 814 G + GY + V TV S + NL Y+V IAA Sbjct: 1030 VT---SRGKLLGYKIFYTMTAVEDLDDWQT--KTVGLTESADLVNLEKFAQYAVAIAARF 1084 Query: 815 IIGLGPFSQKVYFNIDSRSVGLDL 838 GLG S+KV I V L+L Sbjct: 1085 KNGLGRLSEKVTVRIKPEDVPLNL 1108 >UniRef50_UPI00015A60B9 Cluster: UPI00015A60B9 related cluster; n=3; Danio rerio|Rep: UPI00015A60B9 UniRef100 entry - Danio rerio Length = 3050 Score = 115 bits (277), Expect = 7e-24 Identities = 131/527 (24%), Positives = 216/527 (40%), Gaps = 63/527 (11%) Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRY 178 +G V + L G P+P +YW ++ T+ + + GN ++I+ A+++D G Y Sbjct: 684 EGQEVTMSVLVT-GQPKPMLYWLRDRVTIKTGTRHIVQETEEGNFEMIIKSAQRSDTGVY 742 Query: 179 QCIARNAAGTRESAIATLKIHIKPY-----LITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233 C N GT++ L++ +P +I DV+ + G + F+C V G DV Sbjct: 743 TCKIINEYGTKQCE-GKLEVKARPVEPGLAIIRPVRDVMVKAGETALFECHVIGPQDTDV 801 Query: 234 LWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290 W L K+ DG L L++V D G Y+C+ + +++S L V Sbjct: 802 DWLSDGKLIQPALLNCKMHFDGKRCRLLLNSVHEDDSGTYTCKLSTAKEELTSSAKLKVI 861 Query: 291 DP--PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWS-----VEGNRTI-IFPGMSRD 342 P + + V G ARF C +G P P + WS +E N I I R Sbjct: 862 ASIEPLFTRKLDVLEVIEGRNARFDCKVSGTPPPQVIWSHFDRPLEENEDIRILKEGGRH 921 Query: 343 KY---HATAVFDGV-TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398 H + +G+ TV N +++ + A SS + KL P Sbjct: 922 SLIISHVSNEDEGLYTVAARNSHGEDECAAELYVQEPRPAISSQI-AKLEKMPSIPEEPE 980 Query: 399 IITNGPSNQTLP--IKSM----------AVFPCTAICTPEPIIAWYFEGEALIQNHRRNV 446 + N T+P +K + AV C P P I W+ G+ + R + Sbjct: 981 VPENEIERFTMPDFVKPLYDMDVVEGREAVLRCKVAGLPYPTITWFHNGKRIDSTEDRKM 1040 Query: 447 T---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSL 503 T + +LV++ + + G Y CV S++ GK L V D+ L Sbjct: 1041 TQFRDVHSLVVRCVCHAHGGVYKCVISNKVGKATCYSHLYV-------------TDI--L 1085 Query: 504 PGPPT-KPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562 P PP P+ ++T ++TLSW + ++ S + ++ L S W + Sbjct: 1086 PDPPDGAPVVESITGKTITLSWKKPKRLDPSIDPSSLMYAIQQQAL-------GSIQWTI 1138 Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 IA + QT Y + +L G+ Y F V + S S PSP ++ + + D Sbjct: 1139 IASCLKQTTYTISNLSKGVRYAFRVLSITSKAFSKPSPATEPMQLLD 1185 Score = 77.8 bits (183), Expect = 2e-12 Identities = 85/304 (27%), Positives = 128/304 (42%), Gaps = 26/304 (8%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P + D +V Q T++ G P P + W + V + + T + F Sbjct: 669 EPPAFLAVIGDQSVIEGQEVTMSVLVTGQPKPMLYWLRDRVTIKTGTRHIVQETEEGNFE 728 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL---EP-ESKQSAQGDTV 125 SD GVY C+ N YGT + L V E L P G+T Sbjct: 729 MIIKSAQRSDTGVYTCKIINEYGT-KQCEGKLEVKARPVEPGLAIIRPVRDVMVKAGETA 787 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLL-FDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIA 182 + EC G + +V W +G+ + + +MH DG L++ + D+G Y C Sbjct: 788 LFEC-HVIGPQDTDVDWLSDGKLIQPALLNCKMHF-DGKRCRLLLNSVHEDDSGTYTCKL 845 Query: 183 RNAAGTRESAIATLKI--HIKPYLITGPEDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSA 239 A S+ A LK+ I+P L T DV+ G + F C+V G P P V+W Sbjct: 846 STAKEELTSS-AKLKVIASIEP-LFTRKLDVLEVIEGRNARFDCKVSGTPPPQVIWSHF- 902 Query: 240 GGGNMPLGR---VKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP- 292 + PL +++L +G SL + +V DEG Y+ A NS G + L V +P Sbjct: 903 ---DRPLEENEDIRILKEGGRHSLIISHVSNEDEGLYTVAARNSHGEDECAAELYVQEPR 959 Query: 293 PSIN 296 P+I+ Sbjct: 960 PAIS 963 Score = 70.5 bits (165), Expect = 3e-10 Identities = 78/318 (24%), Positives = 122/318 (38%), Gaps = 26/318 (8%) Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR-VKVLDDGSLRL--DN 261 + G + V+ G VT V G P P + W R V+ ++G+ + + Sbjct: 676 VIGDQSVIE--GQEVTMSVLVTGQPKPMLYWLRDRVTIKTGTRHIVQETEEGNFEMIIKS 733 Query: 262 VILADEGEYSCEAENSVGAVSASGYLTV----YDPPSINLSP-NSVNVESGNVARFTCTA 316 +D G Y+C+ N G G L V +P + P V V++G A F C Sbjct: 734 AQRSDTGVYTCKIINEYGTKQCEGKLEVKARPVEPGLAIIRPVRDVMVKAGETALFECHV 793 Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV-LTINDTDKNDSRNTIVCSAV 375 G + + W +G +I P + K H FDG L +N ++DS T C Sbjct: 794 IGPQDTDVDWLSDGK--LIQPALLNCKMH----FDGKRCRLLLNSVHEDDS-GTYTCKLS 846 Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG 435 KL V + + P+ T + A F C TP P + W Sbjct: 847 TAKEELTSSAKLKVIASIE---PLFTRKLDVLEVIEGRNARFDCKVSGTPPPQVIWSHFD 903 Query: 436 EALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492 L +N + +G +L++ + D G YT A + HG+ + L V P P I Sbjct: 904 RPLEENEDIRILKEGGRHSLIISHVSNEDEGLYTVAARNSHGEDECAAELYVQEP-RPAI 962 Query: 493 HFFRAADVSSLPGPPTKP 510 + A + +P P +P Sbjct: 963 S-SQIAKLEKMPSIPEEP 979 Score = 68.1 bits (159), Expect = 1e-09 Identities = 49/158 (31%), Positives = 73/158 (46%), Gaps = 7/158 (4%) Query: 139 NVYWKKNGQTLLFDGDSRMHLV----DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194 +V WK+ G L + L D L + + +D G+ CIA N G+ +S + Sbjct: 1223 SVTWKRIGGVTLSNRPGLFELSMPDDDQHTLKLCKVKSSDVGQLTCIANNKYGS-DSCVL 1281 Query: 195 TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254 TL++ + P T ED+ G + F V G P+PD+LW + + V DD Sbjct: 1282 TLEMAVAPTFETIMEDLDVNVGETPRFAVVVEGKPVPDILWYKGDTLLSESSHFTFVYDD 1341 Query: 255 G--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290 SL + N D G Y+C A+N G+VS LTV+ Sbjct: 1342 NECSLVVLNTQADDSGVYTCTAKNLAGSVSCKAELTVH 1379 Score = 55.2 bits (127), Expect = 1e-05 Identities = 55/215 (25%), Positives = 87/215 (40%), Gaps = 14/215 (6%) Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350 +PP+ +V G + TG+P+P ++W + R I G ++ Sbjct: 669 EPPAFLAVIGDQSVIEGQEVTMSVLVTGQPKPMLYWLRD--RVTIKTGT---RHIVQETE 723 Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410 +G + I ++D+ C +N G+ GKL V + P I + + Sbjct: 724 EGNFEMIIKSAQRSDT-GVYTCKIINEYGTKQCEGKLEVKARPVEPGLAIIRPVRDVMVK 782 Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN--DGT---LVLKDLDKSDSGTY 465 A+F C I + + W +G+ LIQ N DG L+L + + DSGTY Sbjct: 783 AGETALFECHVIGPQDTDVDWLSDGK-LIQPALLNCKMHFDGKRCRLLLNSVHEDDSGTY 841 Query: 466 TCVASSRHGKYVWSGALLVDSPINPNIHFFRAADV 500 TC S+ + S L V + I P F R DV Sbjct: 842 TCKLSTAKEELTSSAKLKVIASIEP--LFTRKLDV 874 Score = 54.0 bits (124), Expect = 2e-05 Identities = 55/195 (28%), Positives = 86/195 (44%), Gaps = 12/195 (6%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD---THRSILPAGGL 66 EAP II++P V + QP ++ + ++ W + G + +S+ +P Sbjct: 1192 EAPVIIDKPDIVYMVEKQPLSITVTL-NHVNASVTWKRIGGVTLSNRPGLFELSMPDDDQ 1250 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126 L+ + SD G C A N YG + S TL +AV F E G+T Sbjct: 1251 HTLKLCKVK-SSDVGQLTCIANNKYG-SDSCVLTLEMAV-APTFETIMEDLDVNVGETPR 1307 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARN 184 + G P P++ W K G TLL + + D +LV+ + + D+G Y C A+N Sbjct: 1308 F-AVVVEGKPVPDILWYK-GDTLLSESSHFTFVYDDNECSLVVLNTQADDSGVYTCTAKN 1365 Query: 185 AAGTRESAIATLKIH 199 AG+ S A L +H Sbjct: 1366 LAGS-VSCKAELTVH 1379 Score = 53.6 bits (123), Expect = 3e-05 Identities = 47/163 (28%), Positives = 73/163 (44%), Gaps = 14/163 (8%) Query: 233 VLWRRSAGG--GNMP-LGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYL 287 V W+R G N P L + + DD +L+L V +D G+ +C A N G+ S L Sbjct: 1224 VTWKRIGGVTLSNRPGLFELSMPDDDQHTLKLCKVKSSDVGQLTCIANNKYGSDSCVLTL 1283 Query: 288 TVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347 + P+ ++V G RF G+P P + W +G+ + + H T Sbjct: 1284 EMAVAPTFETIMEDLDVNVGETPRFAVVVEGKPVPDILW-YKGDTLL------SESSHFT 1336 Query: 348 AVF-DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389 V+ D L + +T +DS C+A N AGS + +LTV Sbjct: 1337 FVYDDNECSLVVLNTQADDS-GVYTCTAKNLAGSVSCKAELTV 1378 Score = 52.4 bits (120), Expect = 7e-05 Identities = 30/83 (36%), Positives = 46/83 (55%), Gaps = 2/83 (2%) Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRR-SAGGGNMPLGRVKVLDD-GSLRLDNVILAD 266 +D VA TG+ V +C + G PLP+V+W++ + N P VK+ + SL + +D Sbjct: 540 QDTVASTGTEVLLKCIISGTPLPEVIWKKDNTEVKNSPTHVVKIEGERHSLLIKWTKPSD 599 Query: 267 EGEYSCEAENSVGAVSASGYLTV 289 G Y+ A N VG VS+S L + Sbjct: 600 AGTYTVTAVNEVGEVSSSATLFI 622 Score = 51.6 bits (118), Expect = 1e-04 Identities = 30/76 (39%), Positives = 44/76 (57%), Gaps = 7/76 (9%) Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV---DGGNLV-IQDARQTDAG 176 +GD V L CLP GSP P++ W K+ + L + D RM+++ DG L+ I + DAG Sbjct: 2388 EGDPVTLSCLPA-GSPHPHISWMKDKKPL--EIDPRMNMISCPDGRQLLMIMKTTKKDAG 2444 Query: 177 RYQCIARNAAGTRESA 192 Y+C+A N T S+ Sbjct: 2445 LYECVAANPLATVTSS 2460 Score = 40.7 bits (91), Expect = 0.24 Identities = 23/83 (27%), Positives = 34/83 (40%), Gaps = 1/83 (1%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P ++ D+ V + A L C+ G P P I W+ G + S R + + L Sbjct: 992 PDFVKPLYDMDVVEGREAVLRCKVAGLPYPTITWFHNGKRIDSTEDRKMTQFRDVHSL-V 1050 Query: 72 THGRVHSDAGVYWCEATNSYGTA 94 H+ GVY C +N G A Sbjct: 1051 VRCVCHAHGGVYKCVISNKVGKA 1073 Score = 40.3 bits (90), Expect = 0.31 Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 2/85 (2%) Query: 37 GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96 G P P I WYKG L+ +H + + L + + D+GVY C A N G+ Sbjct: 1314 GKPVPDILWYKGDTLLSESSHFTFVYDDNECSLVVLNTQA-DDSGVYTCTAKNLAGSVSC 1372 Query: 97 R-NATLHVAVLREEFRLEPESKQSA 120 + T+H + ++++ +P +++ Sbjct: 1373 KAELTVHTNITSKQYKDDPMEDEAS 1397 Score = 39.9 bits (89), Expect = 0.41 Identities = 36/106 (33%), Positives = 45/106 (42%), Gaps = 8/106 (7%) Query: 3 DDYVTSGEAPY---IIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVV-SDTH 57 D YV++GE P + E PL TVA L C G+P P + W K V S TH Sbjct: 520 DSYVSAGEDPLEAPVFEFPLQDTVASTGTEVLLKCIISGTPLPEVIWKKDNTEVKNSPTH 579 Query: 58 RSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103 ++ G SDAG Y A N G S +ATL + Sbjct: 580 --VVKIEGERHSLLIKWTKPSDAGTYTVTAVNEVGEV-SSSATLFI 622 Score = 37.9 bits (84), Expect = 1.7 Identities = 23/77 (29%), Positives = 30/77 (38%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 D + P TL+C GSP P I W K + D +++ L D Sbjct: 2383 DHVLLEGDPVTLSCLPAGSPHPHISWMKDKKPLEIDPRMNMISCPDGRQLLMIMKTTKKD 2442 Query: 80 AGVYWCEATNSYGTARS 96 AG+Y C A N T S Sbjct: 2443 AGLYECVAANPLATVTS 2459 Score = 37.1 bits (82), Expect = 2.9 Identities = 30/95 (31%), Positives = 50/95 (52%), Gaps = 7/95 (7%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVI 167 F + ++ G V+L+C+ G+P P V WKK+ T + + + + ++G +L+I Sbjct: 535 FEFPLQDTVASTGTEVLLKCIIS-GTPLPEVIWKKD-NTEVKNSPTHVVKIEGERHSLLI 592 Query: 168 QDARQTDAGRYQCIARNAAGTRESAIATLKIHIKP 202 + + +DAG Y A N G S+ ATL IKP Sbjct: 593 KWTKPSDAGTYTVTAVNEVG-EVSSSATL--FIKP 624 >UniRef50_Q4RHM3 Cluster: Chromosome 19 SCAF15045, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 19 SCAF15045, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1292 Score = 115 bits (277), Expect = 7e-24 Identities = 86/293 (29%), Positives = 136/293 (46%), Gaps = 21/293 (7%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGLFF 68 AP+ I P ++ +A ++ L CR GG P P I W+ GV + + HR + + Sbjct: 567 APFWISAPRNLILAPNETGILTCRVGGDPKPKITWFINGVSMENAPEDHRRSVDGDTVIL 626 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVL 127 G + VY C A+N +G + NA ++V P + Q + +L Sbjct: 627 SNVQSG----SSAVYQCNASNEFGYLMA-NAFVNVLAEAPRILTPPNQVYQVITNNPALL 681 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 C GSP P + W K+ QT + GD + + + G L I A+ ++G+Y CIA N G Sbjct: 682 HC-ASFGSPIPVITWFKDVQTSVKSGDPYV-IHENGTLEIHVAQLVNSGKYTCIATNNLG 739 Query: 188 TRESAI-------ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238 +E+ + A L ++ PE V Q G S F+C+V DP +P + W + Sbjct: 740 IKENHVFLEVKAGAFLSTSEPTRILKQPEYKVVQRGMSAAFECKVKHDPTLIPTMTWLKD 799 Query: 239 AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291 + G +P V+D +L + +V D+G Y+C S+ SAS LTV + Sbjct: 800 S--GELPDDERFVVDADTLTIMDVTDRDKGTYTCFMNTSLDHDSASAVLTVVE 850 Score = 79.8 bits (188), Expect = 4e-13 Identities = 69/273 (25%), Positives = 103/273 (37%), Gaps = 16/273 (5%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSAGGGNMPLGRVKVLDDGSLRLD 260 P+ I+ P +++ + CRVGGDP P + W N P + +D ++ L Sbjct: 568 PFWISAPRNLILAPNETGILTCRVGGDPKPKITWFINGVSMENAPEDHRRSVDGDTVILS 627 Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVY-DPPSINLSPNSV-NVESGNVARFTCTATG 318 NV Y C A N G + A+ ++ V + P I PN V V + N A C + G Sbjct: 628 NVQSGSSAVYQCNASNEFGYLMANAFVNVLAEAPRILTPPNQVYQVITNNPALLHCASFG 687 Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKY--HATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376 P P + W + ++ S D Y H + +N + N Sbjct: 688 SPIPVITWFKDVQTSV----KSGDPYVIHENGTLEIHVAQLVNSGKYTCIATNNLGIKEN 743 Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE--PIIAWYFE 434 + G TS+ R I P + + A F C P P + W + Sbjct: 744 HVFLEVKAGAFLSTSEPTR----ILKQPEYKVVQRGMSAAFECKVKHDPTLIPTMTWLKD 799 Query: 435 GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467 L + R V D TL + D+ D GTYTC Sbjct: 800 SGELPDDERFVVDAD-TLTIMDVTDRDKGTYTC 831 Score = 65.7 bits (153), Expect = 7e-09 Identities = 44/172 (25%), Positives = 72/172 (41%), Gaps = 4/172 (2%) Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGLFFLRAT 72 ++ P D + ++C A G P P+ W + G V D+ + P G + + Sbjct: 228 LQSPKDYIFDPRENIVIHCEAKGKPHPSFSWTRNGTHFDVEKDSKVLMKPGSGTLVIDIS 287 Query: 73 HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP 132 + + G Y C A N +GTA S + + + E+ +G ++VL+C PP Sbjct: 288 GEKAEAYEGTYQCTAQNDHGTAVSNKIVIRQSRSPLWSKERNEAVVVQKGVSLVLQCRPP 347 Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIAR 183 G P P ++W N L D R+ G+L + D+ Y C AR Sbjct: 348 AGLPPPVIFWMDNNFHRL-PLDKRVSQALNGDLYFSNVLPEDSRPDYICYAR 398 Score = 59.7 bits (138), Expect = 5e-07 Identities = 50/160 (31%), Positives = 73/160 (45%), Gaps = 10/160 (6%) Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQ---DARQTDAGRY 178 + +V+ C +G P P+ W +NG + DS++ + G G LVI + + G Y Sbjct: 240 ENIVIHC-EAKGKPHPSFSWTRNGTHFDVEKDSKVLMKPGSGTLVIDISGEKAEAYEGTY 298 Query: 179 QCIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVLWR 236 QC A+N GT S ++ P + E VV Q G S+ QCR G P P + W Sbjct: 299 QCTAQNDHGTAVSNKIVIRQSRSPLWSKERNEAVVVQKGVSLVLQCRPPAGLPPPVIFWM 358 Query: 237 RSAGGGNMPLG-RVKVLDDGSLRLDNVILAD-EGEYSCEA 274 + +PL RV +G L NV+ D +Y C A Sbjct: 359 DN-NFHRLPLDKRVSQALNGDLYFSNVLPEDSRPDYICYA 397 Score = 53.2 bits (122), Expect = 4e-05 Identities = 45/180 (25%), Positives = 81/180 (45%), Gaps = 16/180 (8%) Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 +P ++ + TC G P+P + W + G + D H +V DG TV+ Sbjct: 573 APRNLILAPNETGILTCRVGGDPKPKITWFING---VSMENAPED--HRRSV-DGDTVIL 626 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMA 415 N ++ S C+A N G + V ++ P I+T P NQ + + A Sbjct: 627 SNV--QSGSSAVYQCNASNEFGYLMANAFVNVLAE---APRILT--PPNQVYQVITNNPA 679 Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND-GTLVLKDLDKSDSGTYTCVASSRHG 474 + C + +P P+I W+ + + +++ V ++ GTL + +SG YTC+A++ G Sbjct: 680 LLHCASFGSPIPVITWFKDVQTSVKSGDPYVIHENGTLEIHVAQLVNSGKYTCIATNNLG 739 Score = 50.8 bits (116), Expect = 2e-04 Identities = 23/65 (35%), Positives = 37/65 (56%), Gaps = 3/65 (4%) Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEA 274 G ++ +C G P PD+ W++ GG +P GRV + +L++ +V+ D GEY C A Sbjct: 462 GETLELECIAEGLPTPDISWQKD--GGELPSGRVSIQTYQKTLKISDVVETDAGEYRCTA 519 Query: 275 ENSVG 279 N +G Sbjct: 520 TNRLG 524 Score = 50.4 bits (115), Expect = 3e-04 Identities = 35/109 (32%), Positives = 51/109 (46%), Gaps = 7/109 (6%) Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175 +K +G+T+ LEC+ G P P++ W+K+G L G + L I D +TDA Sbjct: 456 TKMVLRGETLELECIA-EGLPTPDISWQKDGGELP-SGRVSIQTYQK-TLKISDVVETDA 512 Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR 224 G Y+C A N GT I +P+ VV ++ V QCR Sbjct: 513 GEYRCTATNRLGTAHHIIQVTVKGRRPFW----RQVVEESPLRVGLQCR 557 Score = 37.1 bits (82), Expect = 2.9 Identities = 34/130 (26%), Positives = 51/130 (39%), Gaps = 8/130 (6%) Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS--LRLD-- 260 + P+D + ++ C G P P W R+ ++ ++ GS L +D Sbjct: 228 LQSPKDYIFDPRENIVIHCEAKGKPHPSFSWTRNGTHFDVEKDSKVLMKPGSGTLVIDIS 287 Query: 261 -NVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSPN-SVNVESGNVARFTC-TA 316 A EG Y C A+N G AVS + P + N +V V+ G C Sbjct: 288 GEKAEAYEGTYQCTAQNDHGTAVSNKIVIRQSRSPLWSKERNEAVVVQKGVSLVLQCRPP 347 Query: 317 TGRPEPTMFW 326 G P P +FW Sbjct: 348 AGLPPPVIFW 357 Score = 36.7 bits (81), Expect = 3.9 Identities = 19/56 (33%), Positives = 28/56 (50%) Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 C A P P I+W +G L T TL + D+ ++D+G Y C A++R G Sbjct: 469 CIAEGLPTPDISWQKDGGELPSGRVSIQTYQKTLKISDVVETDAGEYRCTATNRLG 524 Score = 35.9 bits (79), Expect = 6.7 Identities = 29/77 (37%), Positives = 35/77 (45%), Gaps = 14/77 (18%) Query: 23 VARHQPATLNCRAGGSPSPAIRWYK-GGVL----VVSDTHRSILPAGGLFFLRATHGRVH 77 V R + L C A G P+P I W K GG L V T++ L + V Sbjct: 459 VLRGETLELECIAEGLPTPDISWQKDGGELPSGRVSIQTYQKTLKISDV---------VE 509 Query: 78 SDAGVYWCEATNSYGTA 94 +DAG Y C ATN GTA Sbjct: 510 TDAGEYRCTATNRLGTA 526 >UniRef50_UPI00015B5487 Cluster: PREDICTED: similar to leucine-rich repeats and immunoglobulin-like domains 3; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to leucine-rich repeats and immunoglobulin-like domains 3 - Nasonia vitripennis Length = 957 Score = 115 bits (276), Expect = 9e-24 Identities = 81/292 (27%), Positives = 128/292 (43%), Gaps = 19/292 (6%) Query: 113 EPESKQSAQGDTVVLECLPPRGSPEPNVY-WKKNGQTL---LFDGDSRMHLVDGGNLV-- 166 EP+S+ S +G V L+C + P ++ WK + L DS DG L Sbjct: 517 EPKSQLSIKGRNVTLKCRATSTADAPLIFTWKHDNLELRDRTLQMDSEPVFSDGITLASS 576 Query: 167 ---IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223 + + DAG+YQC+ N GT S A + + + P P D+ GS+ +C Sbjct: 577 VLNLVNVTNADAGKYQCMVSNNYGTTYSGKAKISVQVYPSFTKKPHDIRVAAGSTARLEC 636 Query: 224 RVGGDPLPDVLWRRSAGGGNMPLGRV----KVLDDGSLRLDNVILADEGEYSCEAENSVG 279 G P P + W++ GG + P R K+ D L + NV AD G YSC A+N G Sbjct: 637 SAEGLPSPQIAWQKD-GGNDFPAARERRMHKMPTDDVLFIINVKTADSGVYSCTAQNLAG 695 Query: 280 AVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGM 339 ++A+ LT+ + PS + V +G C A+G P P + W G+ P Sbjct: 696 IITANATLTILETPSFVKPMENKEVIAGGSIVMECMASGSPRPQLSWRKNGS-----PLQ 750 Query: 340 SRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTS 391 + +++ TA + ++ +D ++ S N G+S + K TS Sbjct: 751 ATERHFFTAENQLLIIVNTVPSDAGTYECEMINSLGNETGASLLTIKAAPTS 802 Score = 110 bits (264), Expect = 3e-22 Identities = 84/293 (28%), Positives = 132/293 (45%), Gaps = 13/293 (4%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSP-SPAIRWYKGGVLVVSDTHRSI----LPAGGL 66 P I+E+P + + TL CRA + +P I +K L + D + + + G+ Sbjct: 512 PRIVEEPKSQLSIKGRNVTLKCRATSTADAPLIFTWKHDNLELRDRTLQMDSEPVFSDGI 571 Query: 67 FFLRATHGRVH---SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123 + V+ +DAG Y C +N+YGT S A + V V F +P + A G Sbjct: 572 TLASSVLNLVNVTNADAGKYQCMVSNNYGTTYSGKAKISVQVY-PSFTKKPHDIRVAAGS 630 Query: 124 TVVLECLPPRGSPEPNVYWKKN-GQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCI 181 T LEC G P P + W+K+ G + RMH + + L I + + D+G Y C Sbjct: 631 TARLEC-SAEGLPSPQIAWQKDGGNDFPAARERRMHKMPTDDVLFIINVKTADSGVYSCT 689 Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241 A+N AG +A ATL I P + E+ G S+ +C G P P + WR++ Sbjct: 690 AQNLAGI-ITANATLTILETPSFVKPMENKEVIAGGSIVMECMASGSPRPQLSWRKNGSP 748 Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294 ++ L + N + +D G Y CE NS+G + + LT+ P+ Sbjct: 749 LQATERHFFTAENQLLIIVNTVPSDAGTYECEMINSLGNETGASLLTIKAAPT 801 Score = 89.4 bits (212), Expect = 5e-16 Identities = 70/280 (25%), Positives = 111/280 (39%), Gaps = 24/280 (8%) Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL--WRRS---AGGGNMPLGRVKVLDDG 255 KP ++ P+ ++ G +VT +CR ++ W+ + + V DG Sbjct: 511 KPRIVEEPKSQLSIKGRNVTLKCRATSTADAPLIFTWKHDNLELRDRTLQMDSEPVFSDG 570 Query: 256 S------LRLDNVILADEGEYSCEAENSVGAV-SASGYLTVYDPPSINLSPNSVNVESGN 308 L L NV AD G+Y C N+ G S ++V PS P+ + V +G+ Sbjct: 571 ITLASSVLNLVNVTNADAGKYQCMVSNNYGTTYSGKAKISVQVYPSFTKKPHDIRVAAGS 630 Query: 309 VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368 AR C+A G P P + W +G FP + H D + ++ + D Sbjct: 631 TARLECSAEGLPSPQIAWQKDGGND--FPAARERRMHKMPTDDVLFIINVKTADSG---- 684 Query: 369 TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428 C+A N AG LT+ P+ N+ + V C A +P P Sbjct: 685 VYSCTAQNLAGIITANATLTILETPSFVKPM-----ENKEVIAGGSIVMECMASGSPRPQ 739 Query: 429 IAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTC 467 ++W G L R T + L++ + SD+GTY C Sbjct: 740 LSWRKNGSPLQATERHFFTAENQLLIIVNTVPSDAGTYEC 779 Score = 87.0 bits (206), Expect = 3e-15 Identities = 66/219 (30%), Positives = 101/219 (46%), Gaps = 14/219 (6%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG---VLVVSDTHRSILPAGGLFF 68 P ++P D+ VA A L C A G PSP I W K G + +P + F Sbjct: 615 PSFTKKPHDIRVAAGSTARLECSAEGLPSPQIAWQKDGGNDFPAARERRMHKMPTDDVLF 674 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVL 127 + +D+GVY C A N G + NATL +L ++P E+K+ G ++V+ Sbjct: 675 IINVK---TADSGVYSCTAQNLAGII-TANATL--TILETPSFVKPMENKEVIAGGSIVM 728 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 EC+ GSP P + W+KNG L + + L+I + +DAG Y+C N+ G Sbjct: 729 ECM-ASGSPRPQLSWRKNGSPLQAT-ERHFFTAENQLLIIVNTVPSDAGTYECEMINSLG 786 Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVG 226 E+ + L I P + +D++ +V C VG Sbjct: 787 -NETGASLLTIKAAPTSVVNEDDMLGLIIITVVC-CAVG 823 Score = 39.9 bits (89), Expect = 0.41 Identities = 26/83 (31%), Positives = 33/83 (39%), Gaps = 3/83 (3%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P ++ + V + C A GSP P + W K G + T R A + Sbjct: 707 ETPSFVKPMENKEVIAGGSIVMECMASGSPRPQLSWRKNG-SPLQATERHFFTAENQLLI 765 Query: 70 RATHGRVHSDAGVYWCEATNSYG 92 V SDAG Y CE NS G Sbjct: 766 IV--NTVPSDAGTYECEMINSLG 786 Score = 38.3 bits (85), Expect = 1.3 Identities = 47/194 (24%), Positives = 76/194 (39%), Gaps = 16/194 (8%) Query: 290 YDPPSINLSPNSVNVESGNVARFTCTATGRPE-PTMFWSVEGNRTIIFPGMSRDKYHATA 348 + P I P S G C AT + P +F N + + D + Sbjct: 509 FPKPRIVEEPKSQLSIKGRNVTLKCRATSTADAPLIFTWKHDNLELRDRTLQMD---SEP 565 Query: 349 VF-DGVTVLT--INDTD-KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404 VF DG+T+ + +N + N C N G+++ GK ++ + P T P Sbjct: 566 VFSDGITLASSVLNLVNVTNADAGKYQCMVSNNYGTTY-SGKAKISV---QVYPSFTKKP 621 Query: 405 SNQTLPIKSMAVFPCTAICTPEPIIAWYFEG----EALIQNHRRNVTNDGTLVLKDLDKS 460 + + S A C+A P P IAW +G A + + D L + ++ + Sbjct: 622 HDIRVAAGSTARLECSAEGLPSPQIAWQKDGGNDFPAARERRMHKMPTDDVLFIINVKTA 681 Query: 461 DSGTYTCVASSRHG 474 DSG Y+C A + G Sbjct: 682 DSGVYSCTAQNLAG 695 >UniRef50_UPI00015A3FB5 Cluster: hypothetical protein LOC553690; n=3; Danio rerio|Rep: hypothetical protein LOC553690 - Danio rerio Length = 981 Score = 115 bits (276), Expect = 9e-24 Identities = 74/283 (26%), Positives = 128/283 (45%), Gaps = 14/283 (4%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTH-----RSILPAGGL 66 P + +P D+ V +++ A +C+ P PA+ WY LV + + R + + G Sbjct: 190 PQPLVKPEDLVVMKNEEAVFHCQFTAEPMPAVEWYHENELVANKSRTGHFIRVFILSNGS 249 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126 + R + G+Y C A G S A+L +A + + + +S+ + Sbjct: 250 LLITQVKQR---NTGLYKCVAQGPRGPPVSLEASLRIAEIED--MMAKQSRVFSADSLER 304 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186 + C P G P+P V+W++ GQ + D G +L+ D+G Y C A+N A Sbjct: 305 VTCRAPYGHPQPEVWWERAGQRV---PDHGRVFQKGHDLIFSPTHGEDSGIYTCFAQNKA 361 Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 G ++ + T+ + KP + P D + G + C +P P V W R+ + Sbjct: 362 GQKKQEL-TVTVATKPEWVQKPVDSQLEEGRAGFLHCHTRANPEPQVTWYRNLQPISAED 420 Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 R K+ +G+LR++NV + D YSCE+ G V+A + V Sbjct: 421 VRFKLFSNGTLRINNVEVYDGHMYSCESRTEAGRVNAQARVFV 463 Score = 102 bits (245), Expect = 5e-20 Identities = 128/499 (25%), Positives = 201/499 (40%), Gaps = 42/499 (8%) Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75 ++P + A L C + W + G V+++ R L G L F Sbjct: 3 KEPKPQDALHGRSAMLRCEVNDPQGVSYSWIQNGE-PVTNSERRFLDGGNLKFTAIDRTL 61 Query: 76 VHSDAGVYWCEAT-NSYGTA-RSRNATLHVAVLRE-EFRLE-PESKQSAQGDT-VVLECL 130 D+G + C A+ NS G R+ + ++ L L+ PES Q + V+L C Sbjct: 62 ---DSGNFQCIASKNSTGEEERTAETSFNIKWLESGAVSLKSPESVAEIQSSSQVILRCN 118 Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG-TR 189 G P P W K+G T + + + +++ + ++ + +A D G Y C A+NAAG Sbjct: 119 ID-GYPRPTNRWFKDG-TQITEKNYKINNKER-SVTLLNASPDDNGLYHCCAKNAAGQVC 175 Query: 190 ESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW--RRSAGGGNMP 245 S TL I K P + PED+V F C+ +P+P V W Sbjct: 176 SSDNFTLNIIDKSFPQPLVKPEDLVVMKNEEAVFHCQFTAEPMPAVEWYHENELVANKSR 235 Query: 246 LG---RVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNS 301 G RV +L +GSL + V + G Y C A+ G VS L + + + + Sbjct: 236 TGHFIRVFILSNGSLLITQVKQRNTGLYKCVAQGPRGPPVSLEASLRIAEIEDMMAKQSR 295 Query: 302 VNVESGNVARFTCTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360 V + ++ R TC A G P+P ++W G R P R VF L + Sbjct: 296 V-FSADSLERVTCRAPYGHPQPEVWWERAGQRV---PDHGR-------VFQKGHDLIFSP 344 Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420 T DS C A N AG + +LTVT P P + L C Sbjct: 345 THGEDS-GIYTCFAQNKAGQK--KQELTVTV---ATKPEWVQKPVDSQLEEGRAGFLHCH 398 Query: 421 AICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479 PEP + WY + + ++ R + ++GTL + +++ D Y+C + + G+ Sbjct: 399 TRANPEPQVTWYRNLQPISAEDVRFKLFSNGTLRINNVEVYDGHMYSCESRTEAGRVNAQ 458 Query: 480 GA--LLVDSPINPNIHFFR 496 +L P IH+ R Sbjct: 459 ARVFVLAKGRQTPTIHWMR 477 Score = 80.6 bits (190), Expect = 2e-13 Identities = 93/381 (24%), Positives = 148/381 (38%), Gaps = 33/381 (8%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVY-WKKNGQTLLFDGDSRMHLVDGGNLVIQ 168 F EP+ + + G + +L C P+ Y W +NG+ + +S +DGGNL Sbjct: 1 FTKEPKPQDALHGRSAMLRC--EVNDPQGVSYSWIQNGEPVT---NSERRFLDGGNLKFT 55 Query: 169 DARQT-DAGRYQCIARNAAGTRESAIATLKIHIK-----PYLITGPEDVV-AQTGSSVTF 221 +T D+G +QCIA + E A +IK + PE V Q+ S V Sbjct: 56 AIDRTLDSGNFQCIASKNSTGEEERTAETSFNIKWLESGAVSLKSPESVAEIQSSSQVIL 115 Query: 222 QCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVGA 280 +C + G P P W + G + K+ + + S+ L N D G Y C A+N+ G Sbjct: 116 RCNIDGYPRPTNRWFKD--GTQITEKNYKINNKERSVTLLNASPDDNGLYHCCAKNAAGQ 173 Query: 281 VSASGYLT--VYDP--PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF 336 V +S T + D P + P + V A F C T P P + W E N + Sbjct: 174 VCSSDNFTLNIIDKSFPQPLVKPEDLVVMKNEEAVFHCQFTAEPMPAVEWYHE-NELVAN 232 Query: 337 PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF-VRGKLTVTSDDDR 395 + + +G ++T K + C A G + L + +D Sbjct: 233 KSRTGHFIRVFILSNGSLLIT---QVKQRNTGLYKCVAQGPRGPPVSLEASLRIAEIED- 288 Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTA-ICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVL 454 ++ S+ C A P+P + W G+ + +H R L+ Sbjct: 289 -----MMAKQSRVFSADSLERVTCRAPYGHPQPEVWWERAGQR-VPDHGRVFQKGHDLIF 342 Query: 455 KDLDKSDSGTYTCVASSRHGK 475 DSG YTC A ++ G+ Sbjct: 343 SPTHGEDSGIYTCFAQNKAGQ 363 Score = 60.5 bits (140), Expect = 3e-07 Identities = 36/93 (38%), Positives = 47/93 (50%), Gaps = 3/93 (3%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169 F+L+PE+ QG T VL C G P P + WKK + L G SR + G+LVI D Sbjct: 510 FKLKPENTTVYQGHTAVLHC-QATGDPPPFIQWKKKDK-FLEAGKSRFQKMANGSLVIHD 567 Query: 170 ARQTDAGRYQCIARNAAGTRESAIATLKIHIKP 202 D G Y CIA N+ ++ A L + KP Sbjct: 568 VSTEDTGSYTCIAGNSCNIAHTS-AELYVVEKP 599 Score = 48.8 bits (111), Expect = 9e-04 Identities = 25/86 (29%), Positives = 38/86 (44%) Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267 PE+ G + C+ GDP P + W++ R + + +GSL + +V D Sbjct: 514 PENTTVYQGHTAVLHCQATGDPPPFIQWKKKDKFLEAGKSRFQKMANGSLVIHDVSTEDT 573 Query: 268 GEYSCEAENSVGAVSASGYLTVYDPP 293 G Y+C A NS S L V + P Sbjct: 574 GSYTCIAGNSCNIAHTSAELYVVEKP 599 Score = 42.3 bits (95), Expect = 0.078 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 1/69 (1%) Query: 404 PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKDLDKSDS 462 P N T+ AV C A P P I W + + L R +G+LV+ D+ D+ Sbjct: 514 PENTTVYQGHTAVLHCQATGDPPPFIQWKKKDKFLEAGKSRFQKMANGSLVIHDVSTEDT 573 Query: 463 GTYTCVASS 471 G+YTC+A + Sbjct: 574 GSYTCIAGN 582 Score = 40.3 bits (90), Expect = 0.31 Identities = 30/101 (29%), Positives = 44/101 (43%), Gaps = 4/101 (3%) Query: 17 QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV 76 +P + TV + A L+C+A G P P I+W K + + R A G + H Sbjct: 513 KPENTTVYQGHTAVLHCQATGDPPPFIQWKKKDKFLEAGKSRFQKMANGSLVI---HDVS 569 Query: 77 HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK 117 D G Y C A NS A + +A L+V + L + K Sbjct: 570 TEDTGSYTCIAGNSCNIAHT-SAELYVVEKPVQHSLSDDEK 609 Score = 37.1 bits (82), Expect = 2.9 Identities = 27/101 (26%), Positives = 45/101 (44%), Gaps = 6/101 (5%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 VT P +++P+D + + L+C +P P + WY+ + ++ R L + G Sbjct: 370 VTVATKPEWVQKPVDSQLEEGRAGFLHCHTRANPEPQVTWYRNLQPISAEDVRFKLFSNG 429 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVL 106 LR + V+ D +Y CE+ G NA V VL Sbjct: 430 T--LRINNVEVY-DGHMYSCESRTEAGRV---NAQARVFVL 464 >UniRef50_Q7KSE9 Cluster: CG31190-PB, isoform B; n=4; Diptera|Rep: CG31190-PB, isoform B - Drosophila melanogaster (Fruit fly) Length = 2046 Score = 115 bits (276), Expect = 9e-24 Identities = 122/492 (24%), Positives = 196/492 (39%), Gaps = 41/492 (8%) Query: 29 ATLNCRAGGSPSPAIRWY--KGGVLVVSDTHRSILPAGGLFF--LRATHGRVHSDAGVYW 84 A + C A GSP P + W G + R I G L F A + R Y Sbjct: 56 AQVTCTAHGSPPPLVTWVLRDGSLATQVPGLRKISGNGTLHFPPFLAQYYRTDVHEATYR 115 Query: 85 CEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC-LPPRGSPEPNVY-W 142 C A+N GT SRN +H AV+R +F + E+ + G++ +++C +P P V W Sbjct: 116 CRASNEAGTVLSRNVQVH-AVVRRQFHVHVENTEVYLGNSALIKCAIPEYVRPYVRVASW 174 Query: 143 KKNGQTLLFD----GDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAA-GTRESAIAT- 195 + + LL D + L G+L ++ R D ++ C+ N G R+ + A Sbjct: 175 HRGEEILLPDLSDVAGRYVVLAASGDLYVRSVRSEDGLMKFSCLVTNTLNGERQRSDAVM 234 Query: 196 -----LKIHIKPYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRR---SAGGGNMPL 246 L ++ P P ++ + G+ V C + G+P P W R SA +P Sbjct: 235 LQVKELSKNLAPRTTQKPVMEIHVERGNDVHLPCNIQGNPFPIFTWYRVSDSAALYPIPS 294 Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306 + +L L + N D G++ C+A N G L+V S+++ P V S Sbjct: 295 SQRVILSRTLLLIKNADERDAGKWICQASNQFGEQRIEIRLSVNSYVSVHILPQVQIVNS 354 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 G A F CT TG + W G ++ + + F + L + + + D Sbjct: 355 GGTANFNCTTTGSAIDAIDWLHNGKPLQANNALTTGRDNIR--FLSKSSLLVQNVGRRD- 411 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426 R C N S+ +L + D P +I P + C+A +P Sbjct: 412 RGVYQCLVENQRASAQAMAELKL---GDTVPELIYTFIEQNVRP-GPLISLKCSASGSPP 467 Query: 427 PIIAWYFEGEALIQ---NHR----RNVTNDGTLV----LKDLDKSDSGTYTCVASSRHGK 475 P AW + + ++ +HR + V G ++ + + D G Y CVAS+ G Sbjct: 468 PQFAWLLDSQPIMDVSLHHRFAIGQFVDMSGDVISHLNISHVRPDDGGLYKCVASNSMGS 527 Query: 476 YVWSGALLVDSP 487 S L V P Sbjct: 528 VQHSARLNVYGP 539 Score = 101 bits (242), Expect = 1e-19 Identities = 120/502 (23%), Positives = 200/502 (39%), Gaps = 50/502 (9%) Query: 11 APYIIEQP-LDVTVARHQPATLNCRAGGSPSPAIRWYK---GGVLVVSDTHRSILPAGGL 66 AP ++P +++ V R L C G+P P WY+ L + + ++ + L Sbjct: 245 APRTTQKPVMEIHVERGNDVHLPCNIQGNPFPIFTWYRVSDSAALYPIPSSQRVILSRTL 304 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSR---NATLHVAVLREEFRLEPESKQSAQGD 123 ++ R DAG + C+A+N +G R + +V+V + P+ + G Sbjct: 305 LLIKNADER---DAGKWICQASNQFGEQRIEIRLSVNSYVSV-----HILPQVQIVNSGG 356 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTL-----LFDGDSRMHLVDGGNLVIQDARQTDAGRY 178 T C GS + W NG+ L L G + + +L++Q+ + D G Y Sbjct: 357 TANFNC-TTTGSAIDAIDWLHNGKPLQANNALTTGRDNIRFLSKSSLLVQNVGRRDRGVY 415 Query: 179 QCIARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 QC+ N + + A+A LK+ P LI + + G ++ +C G P P W Sbjct: 416 QCLVENQRASAQ-AMAELKLGDTVPELIYTFIEQNVRPGPLISLKCSASGSPPPQFAWLL 474 Query: 238 SAG-------GGNMPLGR-VKVLDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYL 287 + +G+ V + D L + +V D G Y C A NS+G+V S L Sbjct: 475 DSQPIMDVSLHHRFAIGQFVDMSGDVISHLNISHVRPDDGGLYKCVASNSMGSVQHSARL 534 Query: 288 TVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347 VY PP + + + +G C G P + W + ++ + + + Y Sbjct: 535 NVYGPPYVR-AIGPIKAVAGEDIIVHCPFAGYPVEQIRWE-KAHQEL----TTSNHYELA 588 Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG-KLTVTSDDDRPPPIITNGPSN 406 +V DG L I + + + C + AG R +L V S PP+I Sbjct: 589 SVADG-GQLVIKNVEPGRDQGIYTCIVRSRAGEEARRDMQLNVNS-----PPVIEPFKFP 642 Query: 407 QTLPIKSMAVFPCTAICTPEPI-IAWYFEGEAL---IQNHRRNVTNDGTLVLKDLDKSDS 462 + L A C PI +W + ++ +Q + LV KD+ S Sbjct: 643 KNLQEGGRAQITCAVSSGDMPIYFSWKKDDSSIPSSLQITEKKEEFYSLLVFKDISARHS 702 Query: 463 GTYTCVASSRHGKYVWSGALLV 484 G YTC AS+ K ++ L V Sbjct: 703 GKYTCYASNAAAKVNYTAELQV 724 Score = 90.6 bits (215), Expect = 2e-16 Identities = 82/310 (26%), Positives = 126/310 (40%), Gaps = 18/310 (5%) Query: 30 TLNCRAGGSPSPAIRWYKGG--VLVVSDTHR----SILPAGG--LFFLRATHGRVHSDAG 81 +L C A GSP P W ++ VS HR + G + L +H R D G Sbjct: 457 SLKCSASGSPPPQFAWLLDSQPIMDVSLHHRFAIGQFVDMSGDVISHLNISHVRP-DDGG 515 Query: 82 VYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVY 141 +Y C A+NS G+ + +A L+V + P ++ G+ +++ C P G P + Sbjct: 516 LYKCVASNSMGSVQ-HSARLNVYGPPYVRAIGPI--KAVAGEDIIVHC-PFAGYPVEQIR 571 Query: 142 WKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQ-TDAGRYQCIARNAAGTRESAIATLKIH 199 W+K Q L + V DGG LVI++ D G Y CI R+ AG L ++ Sbjct: 572 WEKAHQELTTSNHYELASVADGGQLVIKNVEPGRDQGIYTCIVRSRAGEEARRDMQLNVN 631 Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL-WRR--SAGGGNMPLGRVKVLDDGS 256 P + Q G C V +P W++ S+ ++ + K Sbjct: 632 SPPVIEPFKFPKNLQEGGRAQITCAVSSGDMPIYFSWKKDDSSIPSSLQITEKKEEFYSL 691 Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316 L ++ G+Y+C A N+ V+ + L V P P + GN C A Sbjct: 692 LVFKDISARHSGKYTCYASNAAAKVNYTAELQVRVAPRWRYEPMDTAIMLGNTISINCEA 751 Query: 317 TGRPEPTMFW 326 G P PT+ W Sbjct: 752 EGYPIPTITW 761 Score = 66.9 bits (156), Expect = 3e-09 Identities = 55/223 (24%), Positives = 92/223 (41%), Gaps = 21/223 (9%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTH---RSILPAGGLFFLRATHGRVHSDAGVYWCEA 87 ++C G P IRW K + + H S+ G L GR D G+Y C Sbjct: 558 VHCPFAGYPVEQIRWEKAHQELTTSNHYELASVADGGQLVIKNVEPGR---DQGIYTCIV 614 Query: 88 TNSYGTARSRNATLHV--AVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145 + G R+ L+V + E F+ P++ Q +G + C G WKK+ Sbjct: 615 RSRAGEEARRDMQLNVNSPPVIEPFKF-PKNLQ--EGGRAQITCAVSSGDMPIYFSWKKD 671 Query: 146 GQTLLFDGDSRMHLVDGGN-----LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200 ++ S + + + LV +D +G+Y C A NAA + + A L++ + Sbjct: 672 DSSI----PSSLQITEKKEEFYSLLVFKDISARHSGKYTCYASNAAA-KVNYTAELQVRV 726 Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 P P D G++++ C G P+P + W + G G+ Sbjct: 727 APRWRYEPMDTAIMLGNTISINCEAEGYPIPTITWFKGQGKGS 769 Score = 57.2 bits (132), Expect = 3e-06 Identities = 47/167 (28%), Positives = 74/167 (44%), Gaps = 14/167 (8%) Query: 673 NITIEYEMKTILHSNDVSGFEITS-----LRKYTKYEFFLIPFYKKFEGKPSNSRVAQTL 727 NI + + L S VSG+ T LRKY++Y + G S + T Sbjct: 1043 NINFISVVNSSLKSTIVSGWATTKATLRGLRKYSRYAVTIRAMNSFGSGPWSAAIFGTTA 1102 Query: 728 DDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNV----VVNWLDVPANKSMV 783 + VP+ P N+ L++ ++ + W P LQ GII GY + +V+ +D PA + Sbjct: 1103 EGVPEAAPQNVNCTALSSQSLKISWLEPPLQFHGGIIQGYKILYRPIVHQIDFPAK---L 1159 Query: 784 AINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNID 830 I T + T L L +YS+++ A T G G S ++ D Sbjct: 1160 EIKRTSNLETYL--HTLHKASNYSIRVLAYTATGDGLASHPLFCQTD 1204 Score = 55.2 bits (127), Expect = 1e-05 Identities = 94/424 (22%), Positives = 157/424 (37%), Gaps = 32/424 (7%) Query: 157 MHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTG 216 M L++ LV++ A A +A T + T + P L+ G + TG Sbjct: 1 MSLLEPPCLVLEKALLLGALLLAVLATPLLATSGLRVPTFLLEPAPRLLFGND-----TG 55 Query: 217 SSVTFQCRVGGDPLPDVLW-RRSAGGGNMPLGRVKVLDDGSLRLDNVIL------ADEGE 269 + VT C G P P V W R G K+ +G+L + E Sbjct: 56 AQVT--CTAHGSPPPLVTWVLRDGSLATQVPGLRKISGNGTLHFPPFLAQYYRTDVHEAT 113 Query: 270 YSCEAENSVGAV-SASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTM-FWS 327 Y C A N G V S + + ++ + V GN A C P + S Sbjct: 114 YRCRASNEAGTVLSRNVQVHAVVRRQFHVHVENTEVYLGNSALIKCAIPEYVRPYVRVAS 173 Query: 328 VEGNRTIIFPGMS--RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385 I+ P +S +Y A + V ++ D + +V + +N Sbjct: 174 WHRGEEILLPDLSDVAGRYVVLAASGDLYVRSVRSEDGLMKFSCLVTNTLNGERQRSDAV 233 Query: 386 KLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWY--FEGEAL--IQ 440 L V P T P + + V PC P PI WY + AL I Sbjct: 234 MLQVKELSKNLAPRTTQKPVMEIHVERGNDVHLPCNIQGNPFPIFTWYRVSDSAALYPIP 293 Query: 441 NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADV 500 + +R + + L++K+ D+ D+G + C AS++ G+ L V+S + ++H + Sbjct: 294 SSQRVILSRTLLLIKNADERDAGKWICQASNQFGEQRIEIRLSVNSYV--SVHILPQVQI 351 Query: 501 SSLPGPPTKPITHNVTDTSV-TLSWSQNNK-IGSSSILGY---QVEVFSRETLSGNNTPR 555 + G T T +++ + W N K + +++ L + S+ +L N R Sbjct: 352 VNSGG--TANFNCTTTGSAIDAIDWLHNGKPLQANNALTTGRDNIRFLSKSSLLVQNVGR 409 Query: 556 NSRG 559 RG Sbjct: 410 RDRG 413 Score = 49.2 bits (112), Expect = 7e-04 Identities = 45/187 (24%), Positives = 82/187 (43%), Gaps = 11/187 (5%) Query: 639 IEATPIDSKTIKLMW--EILNFY--YLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEI 694 + T + S+++K+ W L F+ ++G I +RP+ + I++ K + + Sbjct: 1113 VNCTALSSQSLKISWLEPPLQFHGGIIQGYKILYRPIVH-QIDFPAKLEIKRTSNLETYL 1171 Query: 695 TSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSP 754 +L K + Y ++ + +G S+ QT DDVPD P I+ L ++ + W Sbjct: 1172 HTLHKASNYSIRVLAYTATGDGLASHPLFCQTDDDVPDAPAA-IKAAALTADSILISWLT 1230 Query: 755 PELQLQNGIITGYNVVVN--WLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAA 812 P + +NGII+ Y V A MV ++ + T +L Y ++A Sbjct: 1231 P--KNRNGIISHYTVYSREAGRKGQAKTHMVRVDENGYPVT-FESRSLAENQMYEFWVSA 1287 Query: 813 ETIIGLG 819 T +G G Sbjct: 1288 STSVGEG 1294 Score = 42.7 bits (96), Expect = 0.059 Identities = 50/225 (22%), Positives = 89/225 (39%), Gaps = 14/225 (6%) Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTVVLECLPPRGSPEPNV 140 +W A+ S G + R R+ + + A G +VLECL G+P P Sbjct: 1283 FWVSASTSVGEGEPTSVIAQATNTRAPARIASFGQVVRKAVGTGLVLECLAV-GNPTPRA 1341 Query: 141 YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200 W + + F + + GNL I + +G Y C A N G+ E I I + Sbjct: 1342 RWLTRDRPVTFS--PFYEVTNEGNLKIHRVEGSLSGNYTCTANNLFGSDE--IQYQVIAM 1397 Query: 201 KPYLITGPEDVVAQTGSS---VTFQC-RVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS 256 KP + P+ +V + V++ GG PL G + + + + ++ + Sbjct: 1398 KP--PSAPQIIVQYASADSIRVSWDAPDDGGAPLQGYTISYHTAGESWSITEL-LPENNA 1454 Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301 + + ++ A N VG+ AS + V+ + +PN+ Sbjct: 1455 FTISGLKCGNQYIIKMSAHNMVGSGVASEEINVWTKGKASQAPNA 1499 Score = 38.3 bits (85), Expect = 1.3 Identities = 19/59 (32%), Positives = 28/59 (47%) Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 V C A+ P P W + + VTN+G L + ++ S SG YTC A++ G Sbjct: 1328 VLECLAVGNPTPRARWLTRDRPVTFSPFYEVTNEGNLKIHRVEGSLSGNYTCTANNLFG 1386 Score = 35.9 bits (79), Expect = 6.7 Identities = 26/111 (23%), Positives = 48/111 (43%), Gaps = 8/111 (7%) Query: 723 VAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNV-------VVNWLD 775 V +T ++ P P N+++ + + + W P + NG + GY V +N++ Sbjct: 989 VLKTQEEAPTEAPSNVQVQTGGESELIVTWQIPPRESWNGELIGYTVNCSEEKQNINFIS 1048 Query: 776 VPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVY 826 V N S+ + + T + L Y+V I A G GP+S ++ Sbjct: 1049 V-VNSSLKSTIVSGWATTKATLRGLRKYSRYAVTIRAMNSFGSGPWSAAIF 1098 Score = 35.5 bits (78), Expect = 8.9 Identities = 14/38 (36%), Positives = 20/38 (52%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG 48 AP +P+D + ++NC A G P P I W+KG Sbjct: 727 APRWRYEPMDTAIMLGNTISINCEAEGYPIPTITWFKG 764 >UniRef50_Q6IDE9 Cluster: LP21844p; n=2; Sophophora|Rep: LP21844p - Drosophila melanogaster (Fruit fly) Length = 1006 Score = 115 bits (276), Expect = 9e-24 Identities = 122/492 (24%), Positives = 196/492 (39%), Gaps = 41/492 (8%) Query: 29 ATLNCRAGGSPSPAIRWY--KGGVLVVSDTHRSILPAGGLFF--LRATHGRVHSDAGVYW 84 A + C A GSP P + W G + R I G L F A + R Y Sbjct: 56 AQVTCTAHGSPPPLVTWVLRDGSLATQVPGLRKISGNGTLHFPPFLAQYYRTDVHEATYR 115 Query: 85 CEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC-LPPRGSPEPNVY-W 142 C A+N GT SRN +H AV+R +F + E+ + G++ +++C +P P V W Sbjct: 116 CRASNEAGTVLSRNVQVH-AVVRRQFHVHVENTEVYLGNSALIKCAIPEYVRPYVRVASW 174 Query: 143 KKNGQTLLFD----GDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAA-GTRESAIAT- 195 + + LL D + L G+L ++ R D ++ C+ N G R+ + A Sbjct: 175 HRGEEILLPDLSDVAGRYVVLAASGDLYVRSVRSEDGLMKFSCLVTNTLNGERQRSDAVM 234 Query: 196 -----LKIHIKPYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRR---SAGGGNMPL 246 L ++ P P ++ + G+ V C + G+P P W R SA +P Sbjct: 235 LQVKELSKNLAPRTTQKPVMEIHVERGNDVHLPCNIQGNPFPIFTWYRVSDSAALYPIPS 294 Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306 + +L L + N D G++ C+A N G L+V S+++ P V S Sbjct: 295 SQRVILSRTLLLIKNADERDAGKWICQASNQFGEQRIEIRLSVNSYVSVHILPQVQIVNS 354 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 G A F CT TG + W G ++ + + F + L + + + D Sbjct: 355 GGTANFNCTTTGSAIDAIDWLHNGKPLQANNALTTGRDNIR--FLSKSSLLVQNVGRRD- 411 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426 R C N S+ +L + D P +I P + C+A +P Sbjct: 412 RGVYQCLVENQRASAQAMAELKL---GDTVPELIYTFIEQNVRP-GPLISLKCSASGSPP 467 Query: 427 PIIAWYFEGEALIQ---NHR----RNVTNDGTLV----LKDLDKSDSGTYTCVASSRHGK 475 P AW + + ++ +HR + V G ++ + + D G Y CVAS+ G Sbjct: 468 PQFAWLLDSQPIMDVSLHHRFAIGQFVDMSGDVISHLNISHVRPDDGGLYKCVASNSMGS 527 Query: 476 YVWSGALLVDSP 487 S L V P Sbjct: 528 VQHSARLNVYGP 539 Score = 101 bits (242), Expect = 1e-19 Identities = 120/502 (23%), Positives = 200/502 (39%), Gaps = 50/502 (9%) Query: 11 APYIIEQP-LDVTVARHQPATLNCRAGGSPSPAIRWYK---GGVLVVSDTHRSILPAGGL 66 AP ++P +++ V R L C G+P P WY+ L + + ++ + L Sbjct: 245 APRTTQKPVMEIHVERGNDVHLPCNIQGNPFPIFTWYRVSDSAALYPIPSSQRVILSRTL 304 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSR---NATLHVAVLREEFRLEPESKQSAQGD 123 ++ R DAG + C+A+N +G R + +V+V + P+ + G Sbjct: 305 LLIKNADER---DAGKWICQASNQFGEQRIEIRLSVNSYVSV-----HILPQVQIVNSGG 356 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTL-----LFDGDSRMHLVDGGNLVIQDARQTDAGRY 178 T C GS + W NG+ L L G + + +L++Q+ + D G Y Sbjct: 357 TANFNC-TTTGSAIDAIDWLHNGKPLQANNALTTGRDNIRFLSKSSLLVQNVGRRDRGVY 415 Query: 179 QCIARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 QC+ N + + A+A LK+ P LI + + G ++ +C G P P W Sbjct: 416 QCLVENQRASAQ-AMAELKLGDTVPELIYTFIEQNVRPGPLISLKCSASGSPPPQFAWLL 474 Query: 238 SAG-------GGNMPLGR-VKVLDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYL 287 + +G+ V + D L + +V D G Y C A NS+G+V S L Sbjct: 475 DSQPIMDVSLHHRFAIGQFVDMSGDVISHLNISHVRPDDGGLYKCVASNSMGSVQHSARL 534 Query: 288 TVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347 VY PP + + + +G C G P + W + ++ + + + Y Sbjct: 535 NVYGPPYVR-AIGPIKAVAGEDIIVHCPFAGYPVEQIRWE-KAHQEL----TTSNHYELA 588 Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG-KLTVTSDDDRPPPIITNGPSN 406 +V DG L I + + + C + AG R +L V S PP+I Sbjct: 589 SVADG-GQLVIKNVEPGRDQGIYTCIVRSRAGEEARRDMQLNVNS-----PPVIEPFKFP 642 Query: 407 QTLPIKSMAVFPCTAICTPEPI-IAWYFEGEAL---IQNHRRNVTNDGTLVLKDLDKSDS 462 + L A C PI +W + ++ +Q + LV KD+ S Sbjct: 643 KNLQEGGRAQITCAVSSGDMPIYFSWKKDDSSIPSSLQITEKKEEFYSLLVFKDISARHS 702 Query: 463 GTYTCVASSRHGKYVWSGALLV 484 G YTC AS+ K ++ L V Sbjct: 703 GKYTCYASNAAAKVNYTAELQV 724 Score = 99.1 bits (236), Expect = 6e-19 Identities = 118/469 (25%), Positives = 184/469 (39%), Gaps = 44/469 (9%) Query: 30 TLNCRAGGSPSPAIRWYKGG--VLVVSDTHR----SILPAGG--LFFLRATHGRVHSDAG 81 +L C A GSP P W ++ VS HR + G + L +H R D G Sbjct: 457 SLKCSASGSPPPQFAWLLDSQPIMDVSLHHRFAIGQFVDMSGDVISHLNISHVRP-DDGG 515 Query: 82 VYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVY 141 +Y C A+NS G+ + +A L+V + P ++ G+ +++ C P G P + Sbjct: 516 LYKCVASNSMGSVQ-HSARLNVYGPPYVRAIGPI--KAVAGEDIIVHC-PFAGYPVEQIR 571 Query: 142 WKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQ-TDAGRYQCIARNAAGTRESAIATLKIH 199 W+K Q L + V DGG LVI++ D G Y CI R+ AG L ++ Sbjct: 572 WEKAHQELTTSNHYELASVADGGQLVIKNVEPGRDQGIYTCIVRSRAGEEARRDMQLNVN 631 Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL-WRR--SAGGGNMPLGRVKVLDDGS 256 P + Q G C V +P W++ S+ ++ + K Sbjct: 632 SPPVIEPFKFPKNLQEGGRAQITCAVSSGDMPIYFSWKKDDSSIPSSLQITEKKEEFYSL 691 Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316 L ++ G+Y+C A N+ V+ + L V P P + GN C A Sbjct: 692 LVFKDISARHSGKYTCYASNAAAKVNYTAELQVRVAPRWRYEPMDTAIMLGNTISINCEA 751 Query: 317 TGRPEPTMFW-SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375 G P PT+ W +G + F +S + H+ L +N ND +C A Sbjct: 752 EGYPIPTITWFKGQGKGSKDFKPLSM-RNHS---------LLLNLATDNDE-GYYMCQAT 800 Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAW-YF 433 N G+ + ++ R N S + P+ C A EPI I W Sbjct: 801 NEIGAGLKKTIRINVNEPARFEQSARNISSRRNDPV----TLDCHAK-GDEPITIGWTQN 855 Query: 434 EGEALIQNHRRNVTN-------DGTLVLKDLDKSDSGTYTCVASSRHGK 475 G + N R ++ D L + D+ DSG Y C+A + +G+ Sbjct: 856 NGRIDLNNFRFSIAEMKTEKGVDSQLTIGHSDRHDSGVYRCIAENPYGR 904 Score = 93.1 bits (221), Expect = 4e-17 Identities = 94/378 (24%), Positives = 152/378 (40%), Gaps = 27/378 (7%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTH---RSILPAGGLFFLRATHGRVHSDAGVYWCEA 87 ++C G P IRW K + + H S+ G L GR D G+Y C Sbjct: 558 VHCPFAGYPVEQIRWEKAHQELTTSNHYELASVADGGQLVIKNVEPGR---DQGIYTCIV 614 Query: 88 TNSYGTARSRNATLHV--AVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145 + G R+ L+V + E F+ P++ Q +G + C G WKK+ Sbjct: 615 RSRAGEEARRDMQLNVNSPPVIEPFKF-PKNLQ--EGGRAQITCAVSSGDMPIYFSWKKD 671 Query: 146 GQTLLFDGDSRMHLVDGGN-----LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200 ++ S + + + LV +D +G+Y C A NAA + + A L++ + Sbjct: 672 DSSI----PSSLQITEKKEEFYSLLVFKDISARHSGKYTCYASNAAA-KVNYTAELQVRV 726 Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLD 260 P P D G++++ C G P+P + W + G G+ + + + SL L+ Sbjct: 727 APRWRYEPMDTAIMLGNTISINCEAEGYPIPTITWFKGQGKGSKDFKPLS-MRNHSLLLN 785 Query: 261 NVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGR 319 DEG Y C+A N +GA + + + V +P S +++ + C A G Sbjct: 786 LATDNDEGYYMCQATNEIGAGLKKTIRINVNEPARFEQSARNISSRRNDPVTLDCHAKGD 845 Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV-TVLTINDTDKNDSRNTIVCSAVNYA 378 T+ W+ R I R GV + LTI +D++DS C A N Sbjct: 846 EPITIGWTQNNGR--IDLNNFRFSIAEMKTEKGVDSQLTIGHSDRHDS-GVYRCIAENPY 902 Query: 379 GSSFVRGKLTVTSDDDRP 396 G + L V D P Sbjct: 903 GRAEQIIFLAVQERPDTP 920 Score = 89.0 bits (211), Expect = 7e-16 Identities = 126/548 (22%), Positives = 217/548 (39%), Gaps = 55/548 (10%) Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS----DAGVYW 84 A NC GS AI W G + ++ + + FL + V + D GVY Sbjct: 358 ANFNCTTTGSAIDAIDWLHNGKPLQANNALTT-GRDNIRFLSKSSLLVQNVGRRDRGVYQ 416 Query: 85 CEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK 144 C N +A++ A L + E + G + L+C GSP P W Sbjct: 417 CLVENQRASAQAM-AELKLGDTVPELIYTFIEQNVRPGPLISLKC-SASGSPPPQFAWLL 474 Query: 145 NGQTLLFDGDSRMH-------LVD-GGNLV----IQDARQTDAGRYQCIARNAAGTRESA 192 + Q ++ D +H VD G+++ I R D G Y+C+A N+ G+ + + Sbjct: 475 DSQPIM---DVSLHHRFAIGQFVDMSGDVISHLNISHVRPDDGGLYKCVASNSMGSVQHS 531 Query: 193 IATLKIHIKPYL-ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPLGRV 249 A L ++ PY+ GP VA G + C G P+ + W ++ + Sbjct: 532 -ARLNVYGPPYVRAIGPIKAVA--GEDIIVHCPFAGYPVEQIRWEKAHQELTTSNHYELA 588 Query: 250 KVLDDGSLRLDNVILA-DEGEYSCEAENSVGAVSASGY-LTVYDPPSINLSPNSVNVESG 307 V D G L + NV D+G Y+C + G + L V PP I N++ G Sbjct: 589 SVADGGQLVIKNVEPGRDQGIYTCIVRSRAGEEARRDMQLNVNSPPVIEPFKFPKNLQEG 648 Query: 308 NVARFTCTATGRPEPTMF-WSVEGNR--TIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 A+ TC + P F W + + + + ++++++ VF ++ ++ Sbjct: 649 GRAQITCAVSSGDMPIYFSWKKDDSSIPSSLQITEKKEEFYSLLVFKDISA-------RH 701 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424 + T C A N A +L V R P P + + + + C A Sbjct: 702 SGKYT--CYASNAAAKVNYTAELQV-----RVAPRWRYEPMDTAIMLGNTISINCEAEGY 754 Query: 425 PEPIIAWYFEGEALIQNHRRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483 P P I W F+G+ + ++ + +L+L +D G Y C A++ G + Sbjct: 755 PIPTITW-FKGQGKGSKDFKPLSMRNHSLLLNLATDNDEGYYMCQATNEIGAGLKK---T 810 Query: 484 VDSPINPNIHFFRAA-DVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEV 542 + +N F ++A ++SS P H D +T+ W+QNN G + ++ + Sbjct: 811 IRINVNEPARFEQSARNISSRRNDPVTLDCHAKGDEPITIGWTQNN--GRIDLNNFRFSI 868 Query: 543 FSRETLSG 550 +T G Sbjct: 869 AEMKTEKG 876 Score = 62.5 bits (145), Expect = 7e-08 Identities = 52/191 (27%), Positives = 78/191 (40%), Gaps = 16/191 (8%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 AP +P+D + ++NC A G P P I W+KG D + L Sbjct: 727 APRWRYEPMDTAIMLGNTISINCEAEGYPIPTITWFKGQGKGSKDFKPLSMRNHSLLLNL 786 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTVVLE 128 AT +D G Y C+ATN G + ++V E R E ++ S + D V L+ Sbjct: 787 AT----DNDEGYYMCQATNEIGAGLKKTIRINV---NEPARFEQSARNISSRRNDPVTLD 839 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFD----GDSRMHLVDG--GNLVIQDARQTDAGRYQCIA 182 C +G + W +N + + + M G L I + + D+G Y+CIA Sbjct: 840 C-HAKGDEPITIGWTQNNGRIDLNNFRFSIAEMKTEKGVDSQLTIGHSDRHDSGVYRCIA 898 Query: 183 RNAAGTRESAI 193 N G E I Sbjct: 899 ENPYGRAEQII 909 Score = 55.2 bits (127), Expect = 1e-05 Identities = 94/424 (22%), Positives = 157/424 (37%), Gaps = 32/424 (7%) Query: 157 MHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTG 216 M L++ LV++ A A +A T + T + P L+ G + TG Sbjct: 1 MSLLEPPCLVLEKALLLGALLLAVLATPLLATSGLRVPTFLLEPAPRLLFGND-----TG 55 Query: 217 SSVTFQCRVGGDPLPDVLW-RRSAGGGNMPLGRVKVLDDGSLRLDNVIL------ADEGE 269 + VT C G P P V W R G K+ +G+L + E Sbjct: 56 AQVT--CTAHGSPPPLVTWVLRDGSLATQVPGLRKISGNGTLHFPPFLAQYYRTDVHEAT 113 Query: 270 YSCEAENSVGAV-SASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTM-FWS 327 Y C A N G V S + + ++ + V GN A C P + S Sbjct: 114 YRCRASNEAGTVLSRNVQVHAVVRRQFHVHVENTEVYLGNSALIKCAIPEYVRPYVRVAS 173 Query: 328 VEGNRTIIFPGMS--RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385 I+ P +S +Y A + V ++ D + +V + +N Sbjct: 174 WHRGEEILLPDLSDVAGRYVVLAASGDLYVRSVRSEDGLMKFSCLVTNTLNGERQRSDAV 233 Query: 386 KLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWY--FEGEAL--IQ 440 L V P T P + + V PC P PI WY + AL I Sbjct: 234 MLQVKELSKNLAPRTTQKPVMEIHVERGNDVHLPCNIQGNPFPIFTWYRVSDSAALYPIP 293 Query: 441 NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADV 500 + +R + + L++K+ D+ D+G + C AS++ G+ L V+S + ++H + Sbjct: 294 SSQRVILSRTLLLIKNADERDAGKWICQASNQFGEQRIEIRLSVNSYV--SVHILPQVQI 351 Query: 501 SSLPGPPTKPITHNVTDTSV-TLSWSQNNK-IGSSSILGY---QVEVFSRETLSGNNTPR 555 + G T T +++ + W N K + +++ L + S+ +L N R Sbjct: 352 VNSGG--TANFNCTTTGSAIDAIDWLHNGKPLQANNALTTGRDNIRFLSKSSLLVQNVGR 409 Query: 556 NSRG 559 RG Sbjct: 410 RDRG 413 >UniRef50_UPI0000E468FC Cluster: PREDICTED: similar to KLG; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to KLG - Strongylocentrotus purpuratus Length = 1013 Score = 114 bits (275), Expect = 1e-23 Identities = 110/402 (27%), Positives = 171/402 (42%), Gaps = 43/402 (10%) Query: 79 DAGVYWC---EATNSYGTARSRNATLHVAVLREEFRLE---PESKQSAQ-GDTVVLECLP 131 DAG Y C ++ + S A ++V + EE R++ P + + G V L C Sbjct: 55 DAGQYRCVVEPSSTAEAPMSSDPANVNVTWISEELRVQLNRPNLPEDVEEGGKVTLICRA 114 Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191 G+P P V W + QT + G + + G L I+ A D+G Y C+A N AG+ S Sbjct: 115 S-GNPVPMVTWYHD-QTPVVAGSNVD--ISGTRLKIKSATPLDSGIYSCMATNVAGSMPS 170 Query: 192 AIATLKIHI----KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW-RRSAGGGNMPL 246 ++ +I P + P D + G S+ F C+ GDP P V W S GG +P Sbjct: 171 T-ENVQFNIVDSNTPVVEVAPTDAIRVLGDSIMFHCQFSGDPTPPVEWYTTSKAGGEIPP 229 Query: 247 GRVK-------VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299 + ++ +GSL L N+ DEGE+ C ++ G AS LT+ ++N P Sbjct: 230 QLMNDTETGTYIIGNGSLSLANLTAGDEGEFQCVCDSPHGRPFASARLTI---ATVNPLP 286 Query: 300 N--SVNVESGNVARFTCT-----ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352 + + G+ C+ G P P++ W R + G K V + Sbjct: 287 EFEAQLIPEGDTKTINCSYPAGDVGGIPTPSIHWLKPSLREVPLDGT---KTKRVRVEEQ 343 Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412 +L + K+D N C + N AG + K+ V + P IT P + + + Sbjct: 344 KNLLVFDPIKKSDEGN-YTCVSSNMAGETTQILKVVVAT-----APKITTRPVDVHIRER 397 Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVL 454 A C A TP P I+W F + V+ DG+LV+ Sbjct: 398 EEATLRCNATGTPTPTISWTFGTRDITNKQGIEVSADGSLVI 439 Score = 104 bits (250), Expect = 1e-20 Identities = 119/487 (24%), Positives = 205/487 (42%), Gaps = 66/487 (13%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWY----KGGVL---VVSDTHR 58 + P + P D +C+ G P+P + WY GG + +++DT Sbjct: 178 IVDSNTPVVEVAPTDAIRVLGDSIMFHCQFSGDPTPPVEWYTTSKAGGEIPPQLMNDTET 237 Query: 59 S--ILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPES 116 I+ G L T G D G + C + +G + +A L +A + E E+ Sbjct: 238 GTYIIGNGSLSLANLTAG----DEGEFQCVCDSPHGRPFA-SARLTIATVNP--LPEFEA 290 Query: 117 KQSAQGDTVVLECLPPRGS----PEPNVYW-KKNGQTLLFDG--DSRMHLVDGGNLVIQD 169 + +GDT + C P G P P+++W K + + + DG R+ + + NL++ D Sbjct: 291 QLIPEGDTKTINCSYPAGDVGGIPTPSIHWLKPSLREVPLDGTKTKRVRVEEQKNLLVFD 350 Query: 170 -ARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228 +++D G Y C++ N AG + I + + P + T P DV + T +C G Sbjct: 351 PIKKSDEGNYTCVSSNMAG-ETTQILKVVVATAPKITTRPVDVHIREREEATLRCNATGT 409 Query: 229 PLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288 P P + W G ++V DGSL +++ A++ + Sbjct: 410 PTPTISWTFGTRDITNKQG-IEVSADGSLVINS------------------AMTRHNAIL 450 Query: 289 VYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348 ++P I ++ +++ G + R C AT +P + W +G II G D H + Sbjct: 451 KFNPRPIAVT----SLDRGEMNRLVCHATASIQPFIAWHKQG---II--GTWPD--HISE 499 Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408 G VL N + +D+ T +C A + R TV D P + N T Sbjct: 500 PNSG--VLQFNPAEASDA-GTYIC----IASTGLERINTTVRIDVVVKPKFVI--IPNNT 550 Query: 409 LPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467 + + ++ CTA PEP I W + H ++ N GTL+++++ +D+G Y C Sbjct: 551 IGFEGYSLKIDCTAHGDPEPTITWISKPIMNYPEHFTHLPN-GTLIIQEVHANDAGRYQC 609 Query: 468 VASSRHG 474 +A S G Sbjct: 610 IAGSDAG 616 Score = 101 bits (243), Expect = 9e-20 Identities = 90/325 (27%), Positives = 143/325 (44%), Gaps = 30/325 (9%) Query: 30 TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89 TL CRA G+P P + WY VV+ ++ I +G +++ D+G+Y C ATN Sbjct: 109 TLICRASGNPVPMVTWYHDQTPVVAGSNVDI--SGTRLKIKSA---TPLDSGIYSCMATN 163 Query: 90 SYGTARS-RNATLHVAVLREEF-RLEPESKQSAQGDTVVLECLPPRGSPEPNVYW----K 143 G+ S N ++ + P GD+++ C G P P V W K Sbjct: 164 VAGSMPSTENVQFNIVDSNTPVVEVAPTDAIRVLGDSIMFHC-QFSGDPTPPVEWYTTSK 222 Query: 144 KNGQT---LLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200 G+ L+ D ++ +++ G+L + + D G +QC+ + G R A A L I Sbjct: 223 AGGEIPPQLMNDTETGTYIIGNGSLSLANLTAGDEGEFQCVCDSPHG-RPFASARLTIAT 281 Query: 201 KPYLITGPEDVVAQTGSSVTFQCR-----VGGDPLPDVLWRRSAGGGNMPLG-----RVK 250 L ++ + G + T C VGG P P + W + + +PL RV+ Sbjct: 282 VNPLPEFEAQLIPE-GDTKTINCSYPAGDVGGIPTPSIHWLKPSLR-EVPLDGTKTKRVR 339 Query: 251 VLDDGSLRL-DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309 V + +L + D + +DEG Y+C + N G + + V P I P V++ Sbjct: 340 VEEQKNLLVFDPIKKSDEGNYTCVSSNMAGETTQILKVVVATAPKITTRPVDVHIREREE 399 Query: 310 ARFTCTATGRPEPTMFWSVEGNRTI 334 A C ATG P PT+ W+ G R I Sbjct: 400 ATLRCNATGTPTPTISWTF-GTRDI 423 Score = 77.8 bits (183), Expect = 2e-12 Identities = 88/382 (23%), Positives = 155/382 (40%), Gaps = 43/382 (11%) Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180 +G +++L C + NV + + + SR+ + +L I D + DAG+Y+C Sbjct: 5 EGTSIILSCEVDQAE---NVVFSWTLNNVPVEDSSRIFMDTSNSLKIGDVSREDAGQYRC 61 Query: 181 IARNAAGTRESAIATLKIHIKPYLITG-----------PEDVVAQTGSSVTFQCRVGGDP 229 + ++ T E+ +++ ++ I+ PEDV + G VT CR G+P Sbjct: 62 VVEPSS-TAEAPMSSDPANVNVTWISEELRVQLNRPNLPEDV--EEGGKVTLICRASGNP 118 Query: 230 LPDVLWRRS----AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASG 285 +P V W G N+ + + L++ + D G YSC A N G++ ++ Sbjct: 119 VPMVTWYHDQTPVVAGSNVDISGTR------LKIKSATPLDSGIYSCMATNVAGSMPSTE 172 Query: 286 YL--TVYDP--PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRT-IIFPGMS 340 + + D P + ++P G+ F C +G P P + W I P + Sbjct: 173 NVQFNIVDSNTPVVEVAPTDAIRVLGDSIMFHCQFSGDPTPPVEWYTTSKAGGEIPPQLM 232 Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII 400 D T + ++ N T ++ VC + + G F +LT+ + + P Sbjct: 233 NDTETGTYIIGNGSLSLANLTAGDEGEFQCVCDSPH--GRPFASARLTIATVNPLPEFEA 290 Query: 401 TNGPSNQTLPIKSMAVFPCTAIC-TPEPIIAWYFEGEALI-----QNHRRNVTNDGTLVL 454 P T I +P + P P I W + + R V L++ Sbjct: 291 QLIPEGDTKTINCS--YPAGDVGGIPTPSIHWLKPSLREVPLDGTKTKRVRVEEQKNLLV 348 Query: 455 KD-LDKSDSGTYTCVASSRHGK 475 D + KSD G YTCV+S+ G+ Sbjct: 349 FDPIKKSDEGNYTCVSSNMAGE 370 Score = 75.8 bits (178), Expect = 7e-12 Identities = 64/202 (31%), Positives = 99/202 (49%), Gaps = 14/202 (6%) Query: 17 QPLDVT-VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75 +P+ VT + R + L C A S P I W+K G++ H S +G L F A Sbjct: 455 RPIAVTSLDRGEMNRLVCHATASIQPFIAWHKQGIIGTWPDHISEPNSGVLQFNPAEA-- 512 Query: 76 VHSDAGVYWCEATNSYGTARSRNATLHV-AVLREEFRLEPESKQSAQGDTVVLECLPPRG 134 SDAG Y C A S G R N T+ + V++ +F + P + +G ++ ++C G Sbjct: 513 --SDAGTYICIA--STGLERI-NTTVRIDVVVKPKFVIIPNNTIGFEGYSLKIDCTA-HG 566 Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194 PEP + W + ++ + HL +G L+IQ+ DAGRYQCIA + AG + I Sbjct: 567 DPEPTITWIS--KPIMNYPEHFTHLPNG-TLIIQEVHANDAGRYQCIAGSDAGLNTTEIT 623 Query: 195 -TLKIHIKPYLITGPEDVVAQT 215 T++ P + P V+ +T Sbjct: 624 LTVQKGTPPDQVPVPAQVMTRT 645 Score = 57.6 bits (133), Expect = 2e-06 Identities = 75/300 (25%), Positives = 120/300 (40%), Gaps = 46/300 (15%) Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSC 272 G+S+ C V D +V++ + N+P+ R+ + SL++ +V D G+Y C Sbjct: 6 GTSIILSCEV--DQAENVVFSWTLN--NVPVEDSSRIFMDTSNSLKIGDVSREDAGQYRC 61 Query: 273 EAENSVGAVSASGYLTVYDPPSINLS------------PN-SVNVESGNVARFTCTATGR 319 E S A + DP ++N++ PN +VE G C A+G Sbjct: 62 VVEPSSTAEAPMSS----DPANVNVTWISEELRVQLNRPNLPEDVEEGGKVTLICRASGN 117 Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379 P P + W + +T + G + D G T L I DS C A N AG Sbjct: 118 PVPMVTWYHD--QTPVVAGSNVD-------ISG-TRLKIKSATPLDS-GIYSCMATNVAG 166 Query: 380 SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA-- 437 S + D P ++ P++ + +F C P P + WY +A Sbjct: 167 SMPSTENVQFNIVDSNTP-VVEVAPTDAIRVLGDSIMFHCQFSGDPTPPVEWYTTSKAGG 225 Query: 438 ----LIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490 + N T +G+L L +L D G + CV S HG+ ++ A L + +NP Sbjct: 226 EIPPQLMNDTETGTYIIGNGSLSLANLTAGDEGEFQCVCDSPHGR-PFASARLTIATVNP 284 Score = 56.4 bits (130), Expect = 4e-06 Identities = 90/379 (23%), Positives = 138/379 (36%), Gaps = 50/379 (13%) Query: 30 TLNCR-----AGGSPSPAIRWYKGGVLVV--SDTHRSILPAGGLFFLRATHGRVHSDAGV 82 T+NC GG P+P+I W K + V T + L SD G Sbjct: 300 TINCSYPAGDVGGIPTPSIHWLKPSLREVPLDGTKTKRVRVEEQKNLLVFDPIKKSDEGN 359 Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW 142 Y C ++N G + V + P + + L C G+P P + W Sbjct: 360 YTCVSSNMAG--ETTQILKVVVATAPKITTRPVDVHIREREEATLRC-NATGTPTPTISW 416 Query: 143 KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKP 202 + + + + G+LVI N+A TR +AI LK + +P Sbjct: 417 TFGTRDIT--NKQGIEVSADGSLVI----------------NSAMTRHNAI--LKFNPRP 456 Query: 203 YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNV 262 +T + G C P + W + G P + + G L+ + Sbjct: 457 IAVTSLD-----RGEMNRLVCHATASIQPFIAWHKQGIIGTWP-DHISEPNSGVLQFNPA 510 Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEP 322 +D G Y C A + ++ + + V P + PN+ G + CTA G PEP Sbjct: 511 EASDAGTYICIASTGLERINTTVRIDVVVKPKFVIIPNNTIGFEGYSLKIDCTAHGDPEP 570 Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382 T+ W I P M+ + H T + +G L I + ND+ C A + AG + Sbjct: 571 TITW-------ISKPIMNYPE-HFTHLPNG--TLIIQEVHANDA-GRYQCIAGSDAGLNT 619 Query: 383 VRGKLTV---TSDDDRPPP 398 LTV T D P P Sbjct: 620 TEITLTVQKGTPPDQVPVP 638 >UniRef50_A0S6W8 Cluster: Hemicentin-like protein 2; n=2; Spodoptera frugiperda|Rep: Hemicentin-like protein 2 - Spodoptera frugiperda (Fall armyworm) Length = 881 Score = 114 bits (275), Expect = 1e-23 Identities = 135/497 (27%), Positives = 205/497 (41%), Gaps = 54/497 (10%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 VT AP I + P +V + + TL C+ G P P I+W G + G Sbjct: 22 VTGIAAPKI-QMPANVKAVKGKAVTLECKVSGVPKPTIKWQFRG--KSGSKFVPLAETGS 78 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK-QSAQGD- 123 + LR + D G Y C A N+ A+ T + + P + QS +GD Sbjct: 79 V--LRINNVEAKHD-GQYKCVAENA--LAKDEKVTTLIVQETPKIVSRPTTTYQSTEGDA 133 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183 T+ + C+ G P+P + WK +G+ + S + V+ G L+I+ TD Y+C+A Sbjct: 134 TLKIPCVAV-GDPKPTITWKMDGRPIAV--PSSKYAVEDGALIIKYPTVTDTKSYECVAT 190 Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVLW-RRSAGG 241 N AG+ + T I KP + G G V +C+ V G P P++ W ++G Sbjct: 191 NEAGSVTTTFKTF-IRQKPQ-VAGVATKKVYLGMPVDIECKIVKGWPKPNIRWFVNNSGK 248 Query: 242 GNMPLGRVKVLDDGSLRLDNVILADE---GEYSCEAENSVGAVSASGYLTVYDPPSINLS 298 +P+ G+L + +++ A+ G Y C A+N G LTV P I Sbjct: 249 QFVPIA-------GALDVMHIVKAENKHTGRYKCVAQNEAGTAEHITSLTVESRPEIVTK 301 Query: 299 PNSVNVESGNVA-RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 P V G++A + C G P P + W ++G +I P KY FD + L Sbjct: 302 PKPVEAIEGDLAIKIPCDVVGVPRPVITWKLKG--AVIKP---NSKYS----FDNGS-LV 351 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417 I +K+D C A NY GS LT + RP T L Sbjct: 352 IQKPNKSDVAK-YTCEANNYLGSVSSTTDLTF---EKRPSTFGTK--HFVYLLYGENKNI 405 Query: 418 PCTAICTPEPIIAWY-FEGE---ALIQNHRRNVTNDGTLVLKDLDK-SDSGTYTCVASSR 472 C A + + W+ EGE IQ + +V+NDG DK + T+T + + Sbjct: 406 ECEAYRSKSQTLKWFDNEGELNKKSIQITKASVSNDGNYTCHVSDKQGHTETHTYIVN-- 463 Query: 473 HGKYVWSGALLVDSPIN 489 LL D+P+N Sbjct: 464 ---VGGPPKLLADNPLN 477 >UniRef50_UPI0000F1ECB5 Cluster: PREDICTED: similar to novel hemicentin protein; n=1; Danio rerio|Rep: PREDICTED: similar to novel hemicentin protein - Danio rerio Length = 841 Score = 114 bits (274), Expect = 2e-23 Identities = 128/496 (25%), Positives = 196/496 (39%), Gaps = 72/496 (14%) Query: 4 DYVTSGEAPYIIEQPL---DVTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVS-DTHR 58 +Y +AP +I +VT+ Q + CR G P P++ W + G VL + D H Sbjct: 367 EYTIEVQAPPVISGTSGVQEVTIMAGQEVDMQCRVSGRPLPSVEWTHDGEVLSPNGDPHV 426 Query: 59 SILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGT-ARSRNATLHVAVLREEFRLEPESK 117 L G + +++ R D G+Y C ATN+ GT R T+ A L + E Sbjct: 427 EFLEKGQVLRVKSVRPR---DRGLYQCVATNNAGTQTRQFRLTIQAAPLIRDSG-EDSEV 482 Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAG 176 G VL C G P P + W K+ Q ++ ++ GG +L + AR DAG Sbjct: 483 TVVLGFPAVLHC-EVEGIPLPTITWLKDNQPIV--SSPQLTYTQGGQSLRVAAARGEDAG 539 Query: 177 RYQCIARNAAGTRESAIATLKIHIKPY-------LITGPEDVVAQTGSSVTFQCRVGGDP 229 Y C A N AGT TL+I + P L G + + ++T C G P Sbjct: 540 AYTCRATNPAGTAHRHY-TLRIMVPPQIEGDSTILSFGRREEKVRINGTLTLSCLAKGFP 598 Query: 230 LPDVLWRRSAG--GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYL 287 P W + GN G ++ L +DN +L+ EG+Y+C NS G +L Sbjct: 599 EPVTQWFKDGQLLNGNTHSGLS--VNSHMLHVDNAMLSHEGQYTCVVSNSAGEDKRDFHL 656 Query: 288 TVYDPPSINL---------------------SPNSV----NVESGNVARFTCTATGRPEP 322 T+ PP + SP+ + V G+ +C + P P Sbjct: 657 TIQVPPVFHRVINGAADFTLGEREGDEEDPDSPDGMVERREVLLGHSISLSCESNAIPPP 716 Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382 + W +G + G+ H +L I D+ C AVN AG Sbjct: 717 RLSWYRQGRQLTSSDGVVLAPGH---------ILQIPRVQLEDA-GKYTCQAVNEAGEDK 766 Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLP-----IKSMAVFPCTAICTPEPIIAWYFEGEA 437 + L V PP+I +G +++ + + S C P P ++W +G Sbjct: 767 MHYDLEVL-----VPPVI-SGQTDEFMQDVDTVVNSTVSLRCDVSGHPSPSVSWIKDGLP 820 Query: 438 LIQNHRRNVTNDGTLV 453 L + R N+ DG L+ Sbjct: 821 LYSDSRHNILEDGKLL 836 Score = 104 bits (249), Expect = 2e-20 Identities = 115/417 (27%), Positives = 170/417 (40%), Gaps = 38/417 (9%) Query: 79 DAGVYWCEATNSYG-TARSRNATLHVA--VLREEFRLEPESKQSAQGDTVVLECLPPRGS 135 DAGVY C AT++ G T+R + ++ ++ + + G V+L C +GS Sbjct: 58 DAGVYICTATSAVGYTSREMHLIVNSKPRIVGADGSQVTVKMAAEVGSEVILPC-EVQGS 116 Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195 P P V W +NGQT+ + ++ G+L I D R D+ Y C A N AG S Sbjct: 117 PTPLVTWSRNGQTIP-PVTAWFTMLPSGSLKISDVRVVDSKLYTCSAVNPAG-NVSLTYN 174 Query: 196 LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255 L++ KP + P + A G +V C V G+P P V W + + V D Sbjct: 175 LQVQAKPRIHPAPSTLKALIGQTVVLPCVVQGEPSPQVSWLHNG---------LPVASDR 225 Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS--INLSPNSVNV-----ESG- 307 L++ V +D G Y C A NS G + L V P+ + N + V E G Sbjct: 226 MLKIQAVQHSDSGTYRCVARNSAGEDTIQIVLDVLGSPAPQVRWFKNGLEVHMERSEHGV 285 Query: 308 NVARFTCTATGRPEPTM---FWSVEGNRTIIFPGMSRDKYHAT-AVF--DGVTVLTINDT 361 ++A G + F V N +R K T V+ +G +L I Sbjct: 286 SLAEDGALVIGSASASHSGDFKCVATNEAGSVERKTRLKVLETPGVYLQNGKRLLKIYRV 345 Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIKSMAVFPCT 420 ++D C+A N AG + K T + PP I T+G T+ C Sbjct: 346 -QHDHAGRFSCTAQNSAGEA----KREYTIEVQAPPVISGTSGVQEVTIMAGQEVDMQCR 400 Query: 421 AICTPEPIIAWYFEGEALIQN---HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 P P + W +GE L N H + L +K + D G Y CVA++ G Sbjct: 401 VSGRPLPSVEWTHDGEVLSPNGDPHVEFLEKGQVLRVKSVRPRDRGLYQCVATNNAG 457 Score = 104 bits (249), Expect = 2e-20 Identities = 94/330 (28%), Positives = 142/330 (43%), Gaps = 22/330 (6%) Query: 157 MHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL--ITGPEDVVA 213 ++L +G L+ I + AGR+ C A+N+AG + T+++ P + +G ++V Sbjct: 331 VYLQNGKRLLKIYRVQHDHAGRFSCTAQNSAGEAKREY-TIEVQAPPVISGTSGVQEVTI 389 Query: 214 QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG--RVKVLDDGS-LRLDNVILADEGEY 270 G V QCRV G PLP V W G P G V+ L+ G LR+ +V D G Y Sbjct: 390 MAGQEVDMQCRVSGRPLPSVEWTHD-GEVLSPNGDPHVEFLEKGQVLRVKSVRPRDRGLY 448 Query: 271 SCEAENSVGAVSASGYLTVYDPPSINLS--PNSVNVESGNVARFTCTATGRPEPTMFWSV 328 C A N+ G + LT+ P I S + V V G A C G P PT+ W + Sbjct: 449 QCVATNNAGTQTRQFRLTIQAAPLIRDSGEDSEVTVVLGFPAVLHCEVEGIPLPTITW-L 507 Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG--K 386 + N+ I+ S + T + V D C A N AG++ + Sbjct: 508 KDNQPIV----SSPQLTYTQGGQSLRVAAARGEDAG----AYTCRATNPAGTAHRHYTLR 559 Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN-HRRN 445 + V + I++ G + + I C A PEP+ W+ +G+ L N H Sbjct: 560 IMVPPQIEGDSTILSFGRREEKVRINGTLTLSCLAKGFPEPVTQWFKDGQLLNGNTHSGL 619 Query: 446 VTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 N L + + S G YTCV S+ G+ Sbjct: 620 SVNSHMLHVDNAMLSHEGQYTCVVSNSAGE 649 Score = 80.2 bits (189), Expect = 3e-13 Identities = 52/173 (30%), Positives = 77/173 (44%), Gaps = 6/173 (3%) Query: 163 GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI--TGPEDVV---AQTGS 217 G+L I + DAG Y C A +A G + + ++ KP ++ G + V A+ GS Sbjct: 47 GSLYISSPTEEDAGVYICTATSAVGYTSREMHLI-VNSKPRIVGADGSQVTVKMAAEVGS 105 Query: 218 SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENS 277 V C V G P P V W R+ +L GSL++ +V + D Y+C A N Sbjct: 106 EVILPCEVQGSPTPLVTWSRNGQTIPPVTAWFTMLPSGSLKISDVRVVDSKLYTCSAVNP 165 Query: 278 VGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330 G VS + L V P I+ +P+++ G C G P P + W G Sbjct: 166 AGNVSLTYNLQVQAKPRIHPAPSTLKALIGQTVVLPCVVQGEPSPQVSWLHNG 218 Score = 78.2 bits (184), Expect = 1e-12 Identities = 84/292 (28%), Positives = 125/292 (42%), Gaps = 49/292 (16%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFFLRATHGRVHSDAGVYWCEATN 89 L C GSP+P + W + G + T ++LP+G L + + RV D+ +Y C A N Sbjct: 109 LPCEVQGSPTPLVTWSRNGQTIPPVTAWFTMLPSGSL---KISDVRV-VDSKLYTCSAVN 164 Query: 90 SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149 G S L V + P + ++ G TVVL C+ +G P P V W NG + Sbjct: 165 PAGNV-SLTYNLQVQA-KPRIHPAPSTLKALIGQTVVLPCVV-QGEPSPQVSWLHNGLPV 221 Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209 D RM L IQ + +D+G Y+C+ARN+AG E I Sbjct: 222 ASD---RM-------LKIQAVQHSDSGTYRCVARNSAG--EDTI---------------- 253 Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGE 269 +V S Q R + L +V RS G V + +DG+L + + + G+ Sbjct: 254 QIVLDVLGSPAPQVRWFKNGL-EVHMERSEHG-------VSLAEDGALVIGSASASHSGD 305 Query: 270 YSCEAENSVGAVSASGYLTVYDPPSINLSPNS-----VNVESGNVARFTCTA 316 + C A N G+V L V + P + L V+ + RF+CTA Sbjct: 306 FKCVATNEAGSVERKTRLKVLETPGVYLQNGKRLLKIYRVQHDHAGRFSCTA 357 Score = 70.5 bits (165), Expect = 3e-10 Identities = 77/259 (29%), Positives = 106/259 (40%), Gaps = 27/259 (10%) Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-NLSPNS 301 N P+ DGSL + + D G Y C A ++VG S +L V P I + Sbjct: 35 NRPVSAPFEAADGSLYISSPTEEDAGVYICTATSAVGYTSREMHLIVNSKPRIVGADGSQ 94 Query: 302 VNV----ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 V V E G+ C G P P + WS G +TI P ++ T + G L Sbjct: 95 VTVKMAAEVGSEVILPCEVQGSPTPLVTWSRNG-QTI--PPVTA---WFTMLPSG--SLK 146 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417 I+D DS+ CSAVN AG+ + L V + P I PS I V Sbjct: 147 ISDVRVVDSK-LYTCSAVNPAGNVSLTYNLQV-----QAKPRIHPAPSTLKALIGQTVVL 200 Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477 PC P P ++W G V +D L ++ + SDSGTY CVA + G+ Sbjct: 201 PCVVQGEPSPQVSWLHNG--------LPVASDRMLKIQAVQHSDSGTYRCVARNSAGEDT 252 Query: 478 WSGALLVDSPINPNIHFFR 496 L V P + +F+ Sbjct: 253 IQIVLDVLGSPAPQVRWFK 271 Score = 36.3 bits (80), Expect = 5.1 Identities = 26/81 (32%), Positives = 33/81 (40%), Gaps = 12/81 (14%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I P + Q L C G PSP + W G+ V SD + ++A Sbjct: 181 PRIHPAPSTLKALIGQTVVLPCVVQGEPSPQVSWLHNGLPVASDR---------MLKIQA 231 Query: 72 THGRVHSDAGVYWCEATNSYG 92 HSD+G Y C A NS G Sbjct: 232 VQ---HSDSGTYRCVARNSAG 249 >UniRef50_A7RGL8 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 578 Score = 113 bits (273), Expect = 2e-23 Identities = 93/327 (28%), Positives = 138/327 (42%), Gaps = 21/327 (6%) Query: 22 TVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAG 81 TV + TL CR G P P I W++ V +D G + L ++ SDAG Sbjct: 188 TVGKCDKYTLVCRVSGKPKPTITWFRDNTPVHTDNRVVASYEGSVSALELKEMKL-SDAG 246 Query: 82 VYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140 +Y C ATNS G T+ S T+ F + + + + + L+ + G P P V Sbjct: 247 LYKCTATNSQGSTSSSAEVTIKRKDAIPTFVVGLKETEGLESSDMRLD-VKIGGFPRPTV 305 Query: 141 YWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAG--TRESAIATL 196 + K+ L+ D + L DG +L+I + R DAG Y+C+ N G T E+ I Sbjct: 306 EFYKD-YDLIVDSERHKILEDGDRCSLIITNLRPEDAGTYKCVITNLLGVETSEAVIRVQ 364 Query: 197 ------KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA----GGGNMPL 246 + +KP + EDV A V F+ + G P P V W R GG + Sbjct: 365 EREHAPRFDVKPEFLRKVEDVTALETEQVWFEIPIQGYPRPIVEWYRGTTRIKDGGRFTI 424 Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLSPNSVN 303 + D SL +D D G Y C A N G +A L V + P + + Sbjct: 425 SESEENDMYSLVIDEARTEDSGPYKCVASNDAGKTTALLNLDVNEKVVQPEFDKEVKPIE 484 Query: 304 VESGNVARFTCTATGRPEPTMFWSVEG 330 V+ G A + G+P+P + W +G Sbjct: 485 VKHGEEATTSLEIKGKPKPKVTWYKDG 511 Score = 91.9 bits (218), Expect = 1e-16 Identities = 80/276 (28%), Positives = 119/276 (43%), Gaps = 22/276 (7%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 L+ + GG P P + +YK L+V IL G L T+ R DAG Y C TN Sbjct: 293 LDVKIGGFPRPTVEFYKDYDLIVDSERHKILEDGDRCSLIITNLRPE-DAGTYKCVITNL 351 Query: 91 YGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVVLEC------LPPRGSPEPNVYW 142 G S A + V F ++PE + + D LE +P +G P P V W Sbjct: 352 LGVETSE-AVIRVQEREHAPRFDVKPEFLRKVE-DVTALETEQVWFEIPIQGYPRPIVEW 409 Query: 143 KKNGQTLLFDGD----SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198 + G T + DG S D +LVI +AR D+G Y+C+A N AG + +A+ L + Sbjct: 410 YR-GTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDAG-KTTALLNLDV 467 Query: 199 H---IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG--GGNMPLGRVKVLD 253 + ++P + + + G T + G P P V W + + + + D Sbjct: 468 NEKVVQPEFDKEVKPIEVKHGEEATTSLEIKGKPKPKVTWYKDGKVLRESKNIQLKSIGD 527 Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 S+R+ D G Y CEA N G S +T+ Sbjct: 528 TYSIRIVRTAPEDVGTYMCEATNKAGLASRKFDITI 563 Score = 73.3 bits (172), Expect = 4e-11 Identities = 53/198 (26%), Positives = 86/198 (43%), Gaps = 6/198 (3%) Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67 +G+AP + Q + V V L C+ +P P + WYKG LV D R G F Sbjct: 11 AGDAPSLSSQLMPVEVTEGNDIDLVCKVSVNPKPTVTWYKGDALVKLD-DRISAHFDGRF 69 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVV 126 + D G+Y C+ N G A S+ T+ ++ + E + + + V Sbjct: 70 SRLSIQKATKDDEGIYICDVQNELGKAFSKVELTVRKRNVKPQIVGEIKDAEEVERGEVR 129 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGD--SRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 E + G P+P V W + G L DG S D +L ++D ++ D+G Y+ +A+N Sbjct: 130 FE-VRVTGFPKPRVEWYR-GPVHLTDGGRFSISEKEDMYSLTVRDLKRDDSGTYKLVAQN 187 Query: 185 AAGTRESAIATLKIHIKP 202 G + ++ KP Sbjct: 188 TVGKCDKYTLVCRVSGKP 205 Score = 69.7 bits (163), Expect = 4e-10 Identities = 87/364 (23%), Positives = 149/364 (40%), Gaps = 48/364 (13%) Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRY 178 +G+ + L C +P+P V W K + D H DG L IQ A + D G Y Sbjct: 28 EGNDIDLVC-KVSVNPKPTVTWYKGDALVKLDDRISAHF-DGRFSRLSIQKATKDDEGIY 85 Query: 179 QCIARNAAGTRESAI--ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 C +N G S + K ++KP ++ +D V F+ RV G P P V W Sbjct: 86 ICDVQNELGKAFSKVELTVRKRNVKPQIVGEIKDAEEVERGEVRFEVRVTGFPKPRVEWY 145 Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296 R G V + D G + E YS + S + L Sbjct: 146 R---------GPVHLTDGGRFSISE----KEDMYSLTVRDLKRDDSGTYKL--------- 183 Query: 297 LSPNSVNVESGNVARFT--CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG-V 353 ++ N+V G ++T C +G+P+PT+ W + P + ++ A ++G V Sbjct: 184 VAQNTV----GKCDKYTLVCRVSGKPKPTITWFRDNT-----PVHTDNR--VVASYEGSV 232 Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413 + L + + +D+ C+A N GS+ ++T+ D P + + L Sbjct: 233 SALELKEMKLSDA-GLYKCTATNSQGSTSSSAEVTIKRKD-AIPTFVVGLKETEGLESSD 290 Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVAS 470 M + P P + +Y + + ++ + R + DG +L++ +L D+GTY CV + Sbjct: 291 MRL-DVKIGGFPRPTVEFYKDYDLIVDSERHKILEDGDRCSLIITNLRPEDAGTYKCVIT 349 Query: 471 SRHG 474 + G Sbjct: 350 NLLG 353 Score = 60.1 bits (139), Expect = 4e-07 Identities = 46/180 (25%), Positives = 75/180 (41%), Gaps = 6/180 (3%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA--GGLFFL 69 P + + DVT + G P P + WY+G + +I + ++ L Sbjct: 376 PEFLRKVEDVTALETEQVWFEIPIQGYPRPIVEWYRGTTRIKDGGRFTISESEENDMYSL 435 Query: 70 RATHGRVHSDAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128 R D+G Y C A+N G T N ++ V++ EF E + + G+ Sbjct: 436 VIDEART-EDSGPYKCVASNDAGKTTALLNLDVNEKVVQPEFDKEVKPIEVKHGEEATTS 494 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAG 187 L +G P+P V W K+G+ L + ++ + D ++ I D G Y C A N AG Sbjct: 495 -LEIKGKPKPKVTWYKDGKVLRESKNIQLKSIGDTYSIRIVRTAPEDVGTYMCEATNKAG 553 Score = 56.0 bits (129), Expect = 6e-06 Identities = 55/212 (25%), Positives = 89/212 (41%), Gaps = 17/212 (8%) Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350 D PS++ V V GN C + P+PT+ W +G+ + +A F Sbjct: 13 DAPSLSSQLMPVEVTEGNDIDLVCKVSVNPKPTVTW-YKGDALVKLDD------RISAHF 65 Query: 351 DG-VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409 DG + L+I K+D +C N G +F + +LTV + +P + G Sbjct: 66 DGRFSRLSIQKATKDDE-GIYICDVQNELGKAFSKVELTVRKRNVKPQIV---GEIKDAE 121 Query: 410 PIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTY 465 ++ V F P+P + WY L R +++ +L ++DL + DSGTY Sbjct: 122 EVERGEVRFEVRVTGFPKPRVEWYRGPVHLTDGGRFSISEKEDMYSLTVRDLKRDDSGTY 181 Query: 466 TCVASSRHGKY-VWSGALLVDSPINPNIHFFR 496 VA + GK ++ V P I +FR Sbjct: 182 KLVAQNTVGKCDKYTLVCRVSGKPKPTITWFR 213 Score = 46.0 bits (104), Expect = 0.006 Identities = 28/98 (28%), Positives = 41/98 (41%), Gaps = 2/98 (2%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80 + V + AT + G P P + WYK G ++ + + G + +R D Sbjct: 483 IEVKHGEEATTSLEIKGKPKPKVTWYKDGKVLRESKNIQLKSIGDTYSIRIVR-TAPEDV 541 Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ 118 G Y CEATN G A SR + + +L ES Q Sbjct: 542 GTYMCEATNKAGLA-SRKFDITIKGRFRCIKLHRESSQ 578 >UniRef50_A7RGM0 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 621 Score = 113 bits (271), Expect = 4e-23 Identities = 119/462 (25%), Positives = 188/462 (40%), Gaps = 55/462 (11%) Query: 30 TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89 +L+ G P+P + W+K V + L+ G+ D+G Y A + Sbjct: 183 SLDLTVTGKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHSLKIKGGKP-DDSGKYTVVAES 241 Query: 90 SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149 G +R +++ + EF+ + + Q +GD V E G+ L Sbjct: 242 PAGRD-TRTYEVNIKGEKPEFKQKMQPLQVLEGDEKVAE----------------EGRFL 284 Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT--- 206 + D + D +L+I +A+ D+G Y C A N G A A +I I+ L+ Sbjct: 285 IVDDEEG----DLFSLIIGNAKPLDSGVYICQATNDTG---KATAEAEIQIEELLVAPEF 337 Query: 207 GPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLD 260 E+ T +T + V G P P+V W + N PL R+ + G + Sbjct: 338 AEEEATQLTLIEDDDMTLELHVTGKPKPEVHWTKD----NKPLTEDDRIIIDHKGDSCIV 393 Query: 261 NVILA---DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317 +++ D G Y CEA+N G + + + V + P I S + GN TC T Sbjct: 394 DIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNVEEAPEITESLQEMEELEGNPVTLTCKFT 453 Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377 G P P W P D+Y D T L I T ++D +T C A N Sbjct: 454 GTPAPVAEWFKAST-----PLTDTDRYEFIEEGDSYT-LIIKTTVRDDD-DTYKCVASNQ 506 Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEPIIAWYFEG 435 G RG L VT + PP IT + + + K V T + P P + W+ +G Sbjct: 507 VGKVTCRGDLKVT--EKMFPPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKDG 564 Query: 436 EALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHG 474 + + Q+ R N+ G TL + + D+G+YTC A ++ G Sbjct: 565 KPIRQSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMG 606 Score = 88.6 bits (210), Expect = 9e-16 Identities = 118/494 (23%), Positives = 188/494 (38%), Gaps = 53/494 (10%) Query: 11 APYIIEQPL--DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68 AP II+ PL ++ V L C G P + WYK L+ D R + G Sbjct: 70 APIIIK-PLNDEIDVLEGDSVRLECVISGGPDAQVLWYKDDYLLEED-ERIMYDTDGDQH 127 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTVV 126 D Y C TN G+ + ++ EF+ EPE GD V Sbjct: 128 TLIIQSAELDDEAEYKCVVTNIAGSVDVKTEL----IIAPEFQKEPEKSTFDVNTGDDVS 183 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV---DGGNLVIQDARQTDAGRYQCIAR 183 L+ L G P P V W K+ + + G R+ + D +L I+ + D+G+Y +A Sbjct: 184 LD-LTVTGKPTPKVEWFKDDKPV--KGTRRLEVKAKDDEHSLKIKGGKPDDSGKYTVVAE 240 Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 + AG R++ T +++IK G + Q + + GD + A G Sbjct: 241 SPAG-RDTR--TYEVNIK-----GEKPEFKQKMQPLQV---LEGD-------EKVAEEGR 282 Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD----PPSINLSP 299 + + D SL + N D G Y C+A N G +A + + + P Sbjct: 283 FLIVDDEEGDLFSLIIGNAKPLDSGVYICQATNDTGKATAEAEIQIEELLVAPEFAEEEA 342 Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359 + + + TG+P+P + W+ + + D + + D + +T N Sbjct: 343 TQLTLIEDDDMTLELHVTGKPKPEVHWTKDNKPLTEDDRIIIDHKGDSCIVD-IMAVTPN 401 Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419 D+ T C A N AG V + + + ++ P IT + C Sbjct: 402 DS------GTYKCEAKNKAG---VNTRTFIVNVEEAPE--ITESLQEMEELEGNPVTLTC 450 Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGKY 476 TP P+ W+ L R +G TL++K + D TY CVAS++ GK Sbjct: 451 KFTGTPAPVAEWFKASTPLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTYKCVASNQVGKV 510 Query: 477 VWSGALLVDSPINP 490 G L V + P Sbjct: 511 TCRGDLKVTEKMFP 524 Score = 79.0 bits (186), Expect = 7e-13 Identities = 74/279 (26%), Positives = 115/279 (41%), Gaps = 17/279 (6%) Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75 E+ +T+ TL G P P + W K + D R I+ G + Sbjct: 340 EEATQLTLIEDDDMTLELHVTGKPKPEVHWTKDNKPLTEDD-RIIIDHKGDSCIVDIMAV 398 Query: 76 VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGS 135 +D+G Y CEA N G +R ++V E + + +G+ V L C G+ Sbjct: 399 TPNDSGTYKCEAKNKAGV-NTRTFIVNVEEA-PEITESLQEMEELEGNPVTLTC-KFTGT 455 Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAI 193 P P W K T L D D + +G + L+I+ + D Y+C+A N G + + Sbjct: 456 PAPVAEWFK-ASTPLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTYKCVASNQVG-KVTCR 513 Query: 194 ATLKIHIK--PYLITGPE---DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248 LK+ K P IT PE +V + + G+P PDV W + G R Sbjct: 514 GDLKVTEKMFPPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKD-GKPIRQSSR 572 Query: 249 VKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSAS 284 + + G +L + D G Y+CEA+N +G S + Sbjct: 573 LNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSSTT 611 Score = 77.0 bits (181), Expect = 3e-12 Identities = 74/251 (29%), Positives = 105/251 (41%), Gaps = 18/251 (7%) Query: 37 GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG-TAR 95 G P P I+W+K V + + L G D Y C+ATN G T R Sbjct: 4 GEPKPEIQWFKDDKPVKPSQKIRVDYRDDIHSLTIV-GASPDDTAKYTCKATNKSGTTTR 62 Query: 96 SRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155 + N + ++ + E + +GD+V LEC+ G P+ V W K+ LL + + Sbjct: 63 NINVDISAPIIIKPLNDEID---VLEGDSVRLECV-ISGGPDAQVLWYKD-DYLLEEDER 117 Query: 156 RMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVV- 212 M+ DG L+IQ A D Y+C+ N AG S ++ I P PE Sbjct: 118 IMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAG---SVDVKTELIIAPEFQKEPEKSTF 174 Query: 213 -AQTGSSVTFQCRVGGDPLPDVLWRR--SAGGGNMPLGRVKVLDD-GSLRLDNVILADEG 268 TG V+ V G P P V W + G L VK DD SL++ D G Sbjct: 175 DVNTGDDVSLDLTVTGKPTPKVEWFKDDKPVKGTRRL-EVKAKDDEHSLKIKGGKPDDSG 233 Query: 269 EYSCEAENSVG 279 +Y+ AE+ G Sbjct: 234 KYTVVAESPAG 244 Score = 65.3 bits (152), Expect = 1e-08 Identities = 51/199 (25%), Positives = 82/199 (41%), Gaps = 10/199 (5%) Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESA 192 G P+P + W K+ + + R+ D +L I A D +Y C A N +GT Sbjct: 4 GEPKPEIQWFKDDKPVKPSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGT---T 60 Query: 193 IATLKIHIKPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250 + + I +I P +++ G SV +C + G P VLW + R+ Sbjct: 61 TRNINVDISAPIIIKPLNDEIDVLEGDSVRLECVISGGPDAQVLWYKDDYLLEED-ERIM 119 Query: 251 VLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESG 307 DG +L + + L DE EY C N G+V L + ++ +V +G Sbjct: 120 YDTDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIIAPEFQKEPEKSTFDVNTG 179 Query: 308 NVARFTCTATGRPEPTMFW 326 + T TG+P P + W Sbjct: 180 DDVSLDLTVTGKPTPKVEW 198 Score = 64.1 bits (149), Expect = 2e-08 Identities = 51/190 (26%), Positives = 79/190 (41%), Gaps = 10/190 (5%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 EAP I E ++ P TL C+ G+P+P W+K ++DT R G + Sbjct: 427 EAPEITESLQEMEELEGNPVTLTCKFTGTPAPVAEWFKAST-PLTDTDRYEFIEEGDSYT 485 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS---AQGDTVV 126 V D Y C A+N G R + PE + + + +V Sbjct: 486 LIIKTTVRDDDDTYKCVASNQVGKVTCRGDLKVTEKMFPPEITRPERTEKIVLLEKEELV 545 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIAR 183 + + G+P P+V W K+G+ + SR+++ G+ L I DAG Y C A+ Sbjct: 546 IN-VTILGNPRPDVKWFKDGKPI--RQSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQ 602 Query: 184 NAAGTRESAI 193 N GT + I Sbjct: 603 NKMGTSSTTI 612 Score = 52.8 bits (121), Expect = 5e-05 Identities = 57/258 (22%), Positives = 101/258 (39%), Gaps = 19/258 (7%) Query: 224 RVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDD-GSLRLDNVILADEGEYSCEAENSVGA 280 ++ G+P P++ W + P +++V DD SL + D +Y+C+A N G Sbjct: 1 KITGEPKPEIQWFKDDKPVK-PSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGT 59 Query: 281 VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340 + + + + P I + ++V G+ R C +G P+ + W + + Sbjct: 60 TTRNINVDISAPIIIKPLNDEIDVLEGDSVRLECVISGGPDAQVLWYKDD---YLLEEDE 116 Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII 400 R Y DG I + + D C N AGS V+ +L + + + P Sbjct: 117 RIMYDT----DGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIIAPEFQKEPE-- 170 Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDL 457 S + T P P + W+ + + + R V ++ +L +K Sbjct: 171 ---KSTFDVNTGDDVSLDLTVTGKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHSLKIKGG 227 Query: 458 DKSDSGTYTCVASSRHGK 475 DSG YT VA S G+ Sbjct: 228 KPDDSGKYTVVAESPAGR 245 >UniRef50_UPI0000E46E64 Cluster: PREDICTED: similar to SAPS287; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to SAPS287 - Strongylocentrotus purpuratus Length = 1243 Score = 112 bits (269), Expect = 6e-23 Identities = 86/297 (28%), Positives = 130/297 (43%), Gaps = 26/297 (8%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSP-EPNVYWKKNGQTLLFDGD----SRMHLVDGGN 164 F ++PE+ S + D V L C S + + WKK+ + ++ D + R++ G N Sbjct: 474 FSVDPETVTSLKNDNVSLICTAGSTSDVQVTMLWKKD-KAIMEDANPIYFERLN-PSGVN 531 Query: 165 -----LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSV 219 L + ++ D GR+QCI N G S A + +HI P P V + G Sbjct: 532 EYTSVLNLPHIKEADQGRFQCIISNEFGVTYSKKARVTVHIYPSFTVTPRHVSVRVGGIA 591 Query: 220 TFQCRVGGDPLPDVLWRRSAGGGNMPLGR---VKVLDD-GSLRLDNVILADEGEYSCEAE 275 C G P P + W++ GG N P R +KV + +DNV ++D G Y+C A Sbjct: 592 ELPCAATGHPTPKIAWQKD-GGINFPAARQRRIKVKTELAEFYIDNVQISDTGVYTCTAL 650 Query: 276 NSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII 335 N+ G +S + LTV +PP + VE G A C G P P++ W + + Sbjct: 651 NAAGTISTNATLTVLEPPLFTRQMKDLTVEVGEPAVLECNVEGSPRPSIRWFKDEEPFTL 710 Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD 392 GM H T FD ++ +N ++ T C A N G KL VT + Sbjct: 711 SDGM-----HLTD-FDRYLII-MNAAGRDG--GTYTCEATNSLGVRTDTAKLVVTQN 758 Score = 94.7 bits (225), Expect = 1e-17 Identities = 65/230 (28%), Positives = 105/230 (45%), Gaps = 13/230 (5%) Query: 257 LRLDNVILADEGEYSCEAENSVGAV-SASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315 L L ++ AD+G + C N G S +TV+ PS ++P V+V G +A C Sbjct: 537 LNLPHIKEADQGRFQCIISNEFGVTYSKKARVTVHIYPSFTVTPRHVSVRVGGIAELPCA 596 Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375 ATG P P + W +G I FP + + V + I++ +D+ C+A+ Sbjct: 597 ATGHPTPKIAWQKDGG--INFPAARQRRIK---VKTELAEFYIDNVQISDT-GVYTCTAL 650 Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG 435 N AG+ LTV PP+ T + T+ + AV C +P P I W+ + Sbjct: 651 NAAGTISTNATLTVLE-----PPLFTRQMKDLTVEVGEPAVLECNVEGSPRPSIRWFKDE 705 Query: 436 EALIQNHRRNVTN-DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 E + ++T+ D L++ + D GTYTC A++ G + L+V Sbjct: 706 EPFTLSDGMHLTDFDRYLIIMNAAGRDGGTYTCEATNSLGVRTDTAKLVV 755 Score = 77.0 bits (181), Expect = 3e-12 Identities = 65/181 (35%), Positives = 84/181 (46%), Gaps = 10/181 (5%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFFLR 70 P P V+V A L C A G P+P I W K GG+ + R I L Sbjct: 574 PSFTVTPRHVSVRVGGIAELPCAATGHPTPKIAWQKDGGINFPAARQRRIKVKTELAEFY 633 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130 + ++ SD GVY C A N+ GT S NATL V + F + + G+ VLEC Sbjct: 634 IDNVQI-SDTGVYTCTALNAAGTI-STNATLTV-LEPPLFTRQMKDLTVEVGEPAVLEC- 689 Query: 131 PPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGT 188 GSP P++ W K+ + L DG MHL D L+I +A D G Y C A N+ G Sbjct: 690 NVEGSPRPSIRWFKDEEPFTLSDG---MHLTDFDRYLIIMNAAGRDGGTYTCEATNSLGV 746 Query: 189 R 189 R Sbjct: 747 R 747 Score = 53.6 bits (123), Expect = 3e-05 Identities = 34/94 (36%), Positives = 41/94 (43%), Gaps = 4/94 (4%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E P Q D+TV +PA L C GSP P+IRW+K + + Sbjct: 666 EPPLFTRQMKDLTVEVGEPAVLECNVEGSPRPSIRWFKDEEPFTLSDGMHLTDFDRYLII 725 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103 GR D G Y CEATNS G R+ A L V Sbjct: 726 MNAAGR---DGGTYTCEATNSLG-VRTDTAKLVV 755 Score = 41.1 bits (92), Expect = 0.18 Identities = 46/198 (23%), Positives = 78/198 (39%), Gaps = 11/198 (5%) Query: 296 NLSPNSVNVESGNVARFTCTA--TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353 ++ P +V + CTA T + TM W + + ++ + + V + Sbjct: 475 SVDPETVTSLKNDNVSLICTAGSTSDVQVTMLWKKDKAIMEDANPIYFERLNPSGVNEYT 534 Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413 +VL + + D + C N G ++ + K VT P T P + ++ + Sbjct: 535 SVLNLPHIKEAD-QGRFQCIISNEFGVTYSK-KARVTV---HIYPSFTVTPRHVSVRVGG 589 Query: 414 MAVFPCTAICTPEPIIAWYFEG----EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469 +A PC A P P IAW +G A Q + T + ++ SD+G YTC A Sbjct: 590 IAELPCAATGHPTPKIAWQKDGGINFPAARQRRIKVKTELAEFYIDNVQISDTGVYTCTA 649 Query: 470 SSRHGKYVWSGALLVDSP 487 + G + L V P Sbjct: 650 LNAAGTISTNATLTVLEP 667 >UniRef50_UPI0000DB72ED Cluster: PREDICTED: similar to CG33950-PD, isoform D; n=1; Apis mellifera|Rep: PREDICTED: similar to CG33950-PD, isoform D - Apis mellifera Length = 3382 Score = 112 bits (269), Expect = 6e-23 Identities = 96/326 (29%), Positives = 141/326 (43%), Gaps = 23/326 (7%) Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVVLECLPPRGSP 136 D+G+Y C N GT + + V + ++ PE + QG ++C G P Sbjct: 1869 DSGIYKCTTINYIGTVAQKTINITVTPRKPLPTVKVTPEKQTVPQGSIAEVKCFTT-GEP 1927 Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE-SAIAT 195 V W K + + + + G L I + + D G Y C ++G+ E SAI Sbjct: 1928 GVQVKWSKYLEQM----SPNVQQI-GDTLRIVNIQIADRGVYVCRVTGSSGSHEASAIIE 1982 Query: 196 LKIHIKPYLITGPEDVVAQT-GSSVTFQCR-VGGDPLPDVLWRRSAGGGNMPLGRVKVLD 253 ++ P + P++V G S QCR + G P+P + W S G +K L Sbjct: 1983 VEPREPPLVEIYPKNVPPVILGGSTDLQCRAIAGIPIPVLQW--SHEDGRPFASNIKHLP 2040 Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS--VNVESGNVAR 311 G LRL N+ D G Y C A NSVG+ SA+ Y+ V P I ++P S + V+ G+ R Sbjct: 2041 GGVLRLSNITTNDGGSYVCSAVNSVGSNSATVYIEVQSVPIILITPKSGILTVKPGDRVR 2100 Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371 C+ATG P+PT+ WS N I P + + V I ND + Sbjct: 2101 LVCSATGYPQPTVAWSKHMN---IVPLTTNEVIDTPQ----KAVYEIYSASPND-EGSYT 2152 Query: 372 CSAVNYAGSSFVRGKLTVTSDDDRPP 397 C A N AG R + V + PP Sbjct: 2153 CHANNAAGIVEERVYIRVEDSEVYPP 2178 Score = 111 bits (267), Expect = 1e-22 Identities = 130/482 (26%), Positives = 191/482 (39%), Gaps = 53/482 (10%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 AP I P + V A C A G+P P I W + V + ++ G + L+ Sbjct: 1714 APRTIVIPPSLQVVEGHSAEFRCEASGNPPPQIEW----IRVHGPMNPEVIVYNGAWILK 1769 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-------EFRLEPESKQSAQGD 123 A SDA Y C A N+ G R L+V E + P + GD Sbjct: 1770 AVS---KSDAAEYKCIARNNIG-VDERTVILYVKDNFETPPSHSIPPTITPPQWIGSVGD 1825 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183 T+V+ C+P S + NV W + L ++ G L I + D+G Y+C Sbjct: 1826 TIVITCIP---SLDANVTWTRERNIPLPPTANQR----DGILTIVNPSTYDSGIYKCTTI 1878 Query: 184 NAAGTRESAIATLKIHIK---PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 N GT + + + P + PE GS +C G+P V W + Sbjct: 1879 NYIGTVAQKTINITVTPRKPLPTVKVTPEKQTVPQGSIAEVKCFTTGEPGVQVKWSKYL- 1937 Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV--YDPPSINLS 298 V+ + D +LR+ N+ +AD G Y C S G+ AS + V +PP + + Sbjct: 1938 --EQMSPNVQQIGD-TLRIVNIQIADRGVYVCRVTGSSGSHEASAIIEVEPREPPLVEIY 1994 Query: 299 PNSV-NVESGNVARFTCTA-TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356 P +V V G C A G P P + WS E R P S K+ G VL Sbjct: 1995 PKNVPPVILGGSTDLQCRAIAGIPIPVLQWSHEDGR----PFASNIKH-----LPG-GVL 2044 Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK--SM 414 +++ ND + VCSAVN GS+ + V S PII P + L +K Sbjct: 2045 RLSNITTNDG-GSYVCSAVNSVGSNSATVYIEVQS-----VPIILITPKSGILTVKPGDR 2098 Query: 415 AVFPCTAICTPEPIIAW--YFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472 C+A P+P +AW + L N + + +D G+YTC A++ Sbjct: 2099 VRLVCSATGYPQPTVAWSKHMNIVPLTTNEVIDTPQKAVYEIYSASPNDEGSYTCHANNA 2158 Query: 473 HG 474 G Sbjct: 2159 AG 2160 Score = 93.1 bits (221), Expect = 4e-17 Identities = 119/513 (23%), Positives = 201/513 (39%), Gaps = 63/513 (12%) Query: 43 IRWYK-GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATL 101 I+W K GG L RS+ GL +R +V SD+G+Y C+ ++ +N TL Sbjct: 1647 IKWEKEGGQLPPG---RSVDDNHGLLVIRDV--KV-SDSGIYVCQVSDGVHIGY-KNVTL 1699 Query: 102 HVAVLREEFR---------LEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFD 152 V + + P S Q +G + C G+P P + W + + Sbjct: 1700 TVGAFPQSLLDIPTAPRTIVIPPSLQVVEGHSAEFRC-EASGNPPPQIEWIRVHGPM--- 1755 Query: 153 GDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI--------ATLKIHIKPYL 204 + +V G +++ ++DA Y+CIARN G E + T H P Sbjct: 1756 --NPEVIVYNGAWILKAVSKSDAAEYKCIARNNIGVDERTVILYVKDNFETPPSHSIPPT 1813 Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264 IT P+ + G ++ C D +V W R N+PL DG L + N Sbjct: 1814 ITPPQ-WIGSVGDTIVITCIPSLD--ANVTWTRER---NIPLPPTANQRDGILTIVNPST 1867 Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDP----PSINLSPNSVNVESGNVARFTCTATGRP 320 D G Y C N +G V+ P P++ ++P V G++A C TG P Sbjct: 1868 YDSGIYKCTTINYIGTVAQKTINITVTPRKPLPTVKVTPEKQTVPQGSIAEVKCFTTGEP 1927 Query: 321 EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGS 380 + WS + + + + D + ++ I D R VC +GS Sbjct: 1928 GVQVKWS---------KYLEQMSPNVQQIGDTLRIVNIQIAD----RGVYVCRVTGSSGS 1974 Query: 381 SFVRGKLTVTSDDDRPPPIITNGPSN-QTLPIKSMAVFPCTAIC-TPEPIIAWYFEGEAL 438 + V + R PP++ P N + + C AI P P++ W E Sbjct: 1975 HEASAIIEV---EPREPPLVEIYPKNVPPVILGGSTDLQCRAIAGIPIPVLQWSHEDGRP 2031 Query: 439 IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAA 498 ++ +++ G L L ++ +D G+Y C A + G S + ++ P I + Sbjct: 2032 FASNIKHLPG-GVLRLSNITTNDGGSYVCSAVNSVGSN--SATVYIEVQSVPIILITPKS 2088 Query: 499 DVSSL-PGPPTKPITHNVTDTSVTLSWSQNNKI 530 + ++ PG + + T++WS++ I Sbjct: 2089 GILTVKPGDRVRLVCSATGYPQPTVAWSKHMNI 2121 Score = 68.5 bits (160), Expect = 1e-09 Identities = 88/325 (27%), Positives = 126/325 (38%), Gaps = 39/325 (12%) Query: 31 LNCRA-GGSPSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88 L CRA G P P ++W ++ G S+ LP G L T +D G Y C A Sbjct: 2009 LQCRAIAGIPIPVLQWSHEDGRPFASNIKH--LPGGVLRLSNITT----NDGGSYVCSAV 2062 Query: 89 NSYGTARSRNATLHVAVLREEFRL-EPESK--QSAQGDTVVLECLPPRGSPEPNVYWKKN 145 NS G S +AT+++ V L P+S GD V L C G P+P V W K+ Sbjct: 2063 NSVG---SNSATVYIEVQSVPIILITPKSGILTVKPGDRVRLVC-SATGYPQPTVAWSKH 2118 Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK---- 201 + + + I A D G Y C A NAAG E + +++ Sbjct: 2119 MNIVPLTTNEVIDTPQKAVYEIYSASPNDEGSYTCHANNAAGIVEERVY-IRVEDSEVYP 2177 Query: 202 ------PYLITGPEDVVAQ------TGSSVTFQCRVGGDPLPDVL--WRRSAGGGNMPLG 247 P T +D + + G V +C V + + W+R+ +P G Sbjct: 2178 PCRGDVPCHDTTSDDPIPKDYLRIPNGGKVEMRCHVHDNDGNHIYLDWKRTDHRA-LPNG 2236 Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV--SASGYLTVYDPPSINLSPNSVNVE 305 + +G L + V + GEY C + G + A +L V PP I L P V Sbjct: 2237 --SSVHNGVLIIPAVDKSAAGEYVCSGMDQAGNLLFKAKSHLEVLSPPRIVLIPPRQTVR 2294 Query: 306 SGNVARFTCTATGRPEPTMFWSVEG 330 SG C G T+ W+ G Sbjct: 2295 SGESPSIECRTNGDEPMTIEWNAIG 2319 Score = 52.4 bits (120), Expect = 7e-05 Identities = 38/133 (28%), Positives = 60/133 (45%), Gaps = 12/133 (9%) Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264 I GPE + +TG++V + C + + GG +P GR + G L + +V + Sbjct: 1617 IRGPEFQIIETGTTVRYHCSGTSVDNGSLYIKWEKEGGQLPPGRSVDDNHGLLVIRDVKV 1676 Query: 265 ADEGEYSCEAEN-----------SVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313 +D G Y C+ + +VGA S L + P + P S+ V G+ A F Sbjct: 1677 SDSGIYVCQVSDGVHIGYKNVTLTVGAFPQS-LLDIPTAPRTIVIPPSLQVVEGHSAEFR 1735 Query: 314 CTATGRPEPTMFW 326 C A+G P P + W Sbjct: 1736 CEASGNPPPQIEW 1748 Score = 49.2 bits (112), Expect = 7e-04 Identities = 62/260 (23%), Positives = 102/260 (39%), Gaps = 28/260 (10%) Query: 5 YVTSGEAPYIIEQPLD--VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI-L 61 Y+ P I+ P +TV L C A G P P + W K +V T+ I Sbjct: 2073 YIEVQSVPIILITPKSGILTVKPGDRVRLVCSATGYPQPTVAWSKHMNIVPLTTNEVIDT 2132 Query: 62 PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSA 120 P ++ + + +D G Y C A N+ G R + + + R + + Sbjct: 2133 PQKAVYEI---YSASPNDEGSYTCHANNAAGIVEERVYIRVEDSEVYPPCRGDVPCHDTT 2189 Query: 121 QGDTVVLECL--PPRGSPEP----------NVY--WKKNGQTLLFDGDSRMHLVDGGNLV 166 D + + L P G E ++Y WK+ L +G S V G L+ Sbjct: 2190 SDDPIPKDYLRIPNGGKVEMRCHVHDNDGNHIYLDWKRTDHRALPNGSS----VHNGVLI 2245 Query: 167 IQDARQTDAGRYQCIARNAAGTRE-SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV 225 I ++ AG Y C + AG A + L++ P ++ P ++G S + +CR Sbjct: 2246 IPAVDKSAAGEYVCSGMDQAGNLLFKAKSHLEVLSPPRIVLIPPRQTVRSGESPSIECRT 2305 Query: 226 GGDPLPDVLWRRSAGGGNMP 245 GD + W +A G ++P Sbjct: 2306 NGDEPMTIEW--NAIGRSLP 2323 Score = 47.2 bits (107), Expect = 0.003 Identities = 35/96 (36%), Positives = 44/96 (45%), Gaps = 8/96 (8%) Query: 204 LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVI 263 L T P + V + V FQCR G V W R G N+PL +G L + N+ Sbjct: 179 LKTYPSEQVIKESREVVFQCRDEGPLRAKVRWLR---GNNLPLPSGSRDINGRLEIPNIQ 235 Query: 264 LADEGEYSCEAEN---SVGAVSASGYLTV--YDPPS 294 L G Y CEA + S S YLTV +DPP+ Sbjct: 236 LNHSGSYICEAVDYPPSTPGQQVSVYLTVEKFDPPA 271 Score = 47.2 bits (107), Expect = 0.003 Identities = 50/200 (25%), Positives = 77/200 (38%), Gaps = 12/200 (6%) Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLR-EEFRLEPESKQSAQGDTVVLECLPPRGSPE 137 D+G Y C+ S+G + S L+V+ +E GDT+ + C G+ Sbjct: 2394 DSGRYICQIQTSHGVS-SDYINLNVSPTPIPAVSVEVSQDPVNIGDTIDIRCACS-GTHN 2451 Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197 P +W + L + G L + + +D+G Y+C A G + L Sbjct: 2452 PRYHWSRPNHMSLPENAQEY----GNVLRLSNVAVSDSGLYRCTADTPEGVFKQDF-NLV 2506 Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257 +H E A GSS+ CR DP W + GG +P + + L Sbjct: 2507 VHGGNNDAPAIETKYAPYGSSLEMDCRPNIDPPMKFHWSKL--GGFLPPDAQ--IFESKL 2562 Query: 258 RLDNVILADEGEYSCEAENS 277 +L NV D G Y C N+ Sbjct: 2563 KLINVKAEDAGTYICSVNNN 2582 Score = 46.4 bits (105), Expect = 0.005 Identities = 53/198 (26%), Positives = 78/198 (39%), Gaps = 26/198 (13%) Query: 288 TVYDPPSINL---SPNSVNVESGNVARFTCTATGRPEPTMF--WSVEGNRTIIFPGMSRD 342 T PP I + P +E+G R+ C+ T +++ W EG + + PG S D Sbjct: 1606 TTITPPMILIYIRGPEFQIIETGTTVRYHCSGTSVDNGSLYIKWEKEGGQ--LPPGRSVD 1663 Query: 343 KYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTS------DDDRP 396 H +L I D +DS VC + + LTV + D Sbjct: 1664 DNHG--------LLVIRDVKVSDS-GIYVCQVSDGVHIGYKNVTLTVGAFPQSLLDIPTA 1714 Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKD 456 P I PS Q + S A F C A P P I W + + + +G +LK Sbjct: 1715 PRTIVIPPSLQVVEGHS-AEFRCEASGNPPPQIEWIRVHGPM---NPEVIVYNGAWILKA 1770 Query: 457 LDKSDSGTYTCVASSRHG 474 + KSD+ Y C+A + G Sbjct: 1771 VSKSDAAEYKCIARNNIG 1788 Score = 44.4 bits (100), Expect = 0.019 Identities = 49/213 (23%), Positives = 79/213 (37%), Gaps = 18/213 (8%) Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181 G V L+C+ + ++W ++GQ L S + ++ L + R D+GRY C Sbjct: 2350 GQPVRLQCMVRE---KATIHWVRDGQPL----PSNVR-IEEDYLELPRVRPEDSGRYICQ 2401 Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT----GSSVTFQCRVGGDPLPDVLWRR 237 + + G I +++ P I V+Q G ++ +C G P W R Sbjct: 2402 IQTSHGVSSDYI---NLNVSPTPIPAVSVEVSQDPVNIGDTIDIRCACSGTHNPRYHWSR 2458 Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297 +M L LRL NV ++D G Y C A+ G L V+ + Sbjct: 2459 P---NHMSLPENAQEYGNVLRLSNVAVSDSGLYRCTADTPEGVFKQDFNLVVHGGNNDAP 2515 Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330 + + G+ C P WS G Sbjct: 2516 AIETKYAPYGSSLEMDCRPNIDPPMKFHWSKLG 2548 Score = 43.6 bits (98), Expect = 0.034 Identities = 31/113 (27%), Positives = 46/113 (40%), Gaps = 4/113 (3%) Query: 175 AGRYQCIARNAAGTRESAI--ATLKIHIKPYLITGPED--VVAQTGSSVTFQCRVGGDPL 230 A QCI ++ E A+ ++ P I P + G +T C G P Sbjct: 368 ASNNQCIPKSYHCDMEKDCLDASDEVGCSPVFIVKPPVPMITLNIGEVLTITCTAIGVPT 427 Query: 231 PDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSA 283 P++ WR + G + G+L N+ D+G YSCE N+ G V A Sbjct: 428 PEINWRLNWGHVPPKCTMTSINGTGTLTCPNIQPEDQGAYSCEGLNNAGFVFA 480 Score = 35.9 bits (79), Expect = 6.7 Identities = 20/68 (29%), Positives = 28/68 (41%), Gaps = 1/68 (1%) Query: 408 TLPIKSMAVFPCTAICTPEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYT 466 TL I + CTAI P P I W G + ++ GTL ++ D G Y+ Sbjct: 409 TLNIGEVLTITCTAIGVPTPEINWRLNWGHVPPKCTMTSINGTGTLTCPNIQPEDQGAYS 468 Query: 467 CVASSRHG 474 C + G Sbjct: 469 CEGLNNAG 476 Score = 35.9 bits (79), Expect = 6.7 Identities = 40/184 (21%), Positives = 69/184 (37%), Gaps = 16/184 (8%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 + C G+ +P W + + + + + G + LR ++ V SD+G+Y C A Sbjct: 2442 IRCACSGTHNPRYHWSRPNHMSLPENAQEY---GNV--LRLSNVAV-SDSGLYRCTADTP 2495 Query: 91 YGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149 G + N +H E+K + G ++ ++C P P +W K G L Sbjct: 2496 EGVFKQDFNLVVHGG---NNDAPAIETKYAPYGSSLEMDCRP-NIDPPMKFHWSKLGGFL 2551 Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209 D + L + + + DAG Y C N E + + PY P Sbjct: 2552 PPDAQ-----IFESKLKLINVKAEDAGTYICSVNNNHENIEIPTVLVVTGVVPYFSQAPR 2606 Query: 210 DVVA 213 +A Sbjct: 2607 SFIA 2610 >UniRef50_Q4SPP9 Cluster: Chromosome 16 SCAF14537, whole genome shotgun sequence; n=2; cellular organisms|Rep: Chromosome 16 SCAF14537, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 838 Score = 112 bits (269), Expect = 6e-23 Identities = 76/237 (32%), Positives = 114/237 (48%), Gaps = 16/237 (6%) Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVN 303 +G+ +VL +G+L + N + D G+Y C AEN G L+V PS L P + Sbjct: 527 MGKYEVLHNGTLSIHNTNIKDRGQYLCTAENDHGMDKLLVTLSVVAYPSRILEPKLRQIK 586 Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363 V +GN A TC A GRP P++ W + NRT + G++ + + +G L I D Sbjct: 587 VLAGNTAEVTCKAEGRPTPSISW-ILPNRTQV-RGLNTEWGRVSVTPEG--ALVIKDLSM 642 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423 ND R C A N AG +L V + PP I+ + + A+ PCT Sbjct: 643 ND-RGHYKCIASNQAGGDIATVQLHVVA---APPGIMEEKRQQVNIGVSQSALLPCTGQG 698 Query: 424 TPEPIIAW------YFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 P+P I W + + L N R V +GTL ++++ ++DSG Y C+A+S G Sbjct: 699 RPQPTIHWVLHDGSHLPSKRLTSNTRTLVHENGTLYIENVTQADSGKYECIATSSTG 755 Score = 98.3 bits (234), Expect = 1e-18 Identities = 79/309 (25%), Positives = 120/309 (38%), Gaps = 15/309 (4%) Query: 146 GQTLLFDGD-SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL 204 G +++ G + ++ G L I + D G+Y C A N G + + TL + P Sbjct: 518 GNSIIIKGKMGKYEVLHNGTLSIHNTNIKDRGQYLCTAENDHGM-DKLLVTLSVVAYPSR 576 Query: 205 ITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGGGNMPLGRVKVLDDGSLR 258 I P+ + G++ C+ G P P + W R G N GRV V +G+L Sbjct: 577 ILEPKLRQIKVLAGNTAEVTCKAEGRPTPSISWILPNRTQVRGLNTEWGRVSVTPEGALV 636 Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYL-TVYDPPSI-NLSPNSVNVESGNVARFTCTA 316 + ++ + D G Y C A N G A+ L V PP I VN+ A CT Sbjct: 637 IKDLSMNDRGHYKCIASNQAGGDIATVQLHVVAAPPGIMEEKRQQVNIGVSQSALLPCTG 696 Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376 GRP+PT+ W + + P T V + T+ N T + + C A + Sbjct: 697 QGRPQPTIHWVLHDGSHL--PSKRLTSNTRTLVHENGTLYIENVTQADSGK--YECIATS 752 Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436 GS R + V P I+ L C+A+ P P I W + Sbjct: 753 STGSE-KRVVILVVEKAASAPHIVETFQRKMELFFGDQLRLNCSAVGDPRPKIMWRLPSK 811 Query: 437 ALIQNHRRN 445 A++ N Sbjct: 812 AMLDQGHSN 820 Score = 70.9 bits (166), Expect = 2e-10 Identities = 59/239 (24%), Positives = 105/239 (43%), Gaps = 24/239 (10%) Query: 14 IIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-----SILPAGGLF 67 I+E L + V A + C+A G P+P+I W V + S+ P G L Sbjct: 577 ILEPKLRQIKVLAGNTAEVTCKAEGRPTPSISWILPNRTQVRGLNTEWGRVSVTPEGALV 636 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GDT 124 + +D G Y C A+N G AT+ + V+ + E +Q + Sbjct: 637 IKDLS----MNDRGHYKCIASNQAG---GDIATVQLHVVAAPPGIMEEKRQQVNIGVSQS 689 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLL----FDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180 +L C +G P+P ++W + + L ++R + + G L I++ Q D+G+Y+C Sbjct: 690 ALLPC-TGQGRPQPTIHWVLHDGSHLPSKRLTSNTRTLVHENGTLYIENVTQADSGKYEC 748 Query: 181 IARNAAGTRESAIATL--KIHIKPYLI-TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 IA ++ G+ + + + K P+++ T + G + C GDP P ++WR Sbjct: 749 IATSSTGSEKRVVILVVEKAASAPHIVETFQRKMELFFGDQLRLNCSAVGDPRPKIMWR 807 Score = 41.9 bits (94), Expect = 0.10 Identities = 40/149 (26%), Positives = 61/149 (40%), Gaps = 15/149 (10%) Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRW--YKGGVL----VVSDTHRSILPAGGLFFL 69 E+ V + Q A L C G P P I W + G L + S+T + G L+ Sbjct: 677 EKRQQVNIGVSQSALLPCTGQGRPQPTIHWVLHDGSHLPSKRLTSNTRTLVHENGTLYIE 736 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GDTVV 126 T +D+G Y C AT+S G+ + R L V + ++ + GD + Sbjct: 737 NVT----QADSGKYECIATSSTGSEK-RVVILVVEKAASAPHIVETFQRKMELFFGDQLR 791 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDS 155 L C G P P + W+ + +L G S Sbjct: 792 LNC-SAVGDPRPKIMWRLPSKAMLDQGHS 819 >UniRef50_A7RQE6 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 807 Score = 112 bits (269), Expect = 6e-23 Identities = 103/346 (29%), Positives = 154/346 (44%), Gaps = 45/346 (13%) Query: 158 HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL-----------KIHIKPYLIT 206 H + LVI++ R +D G Y C ARN G R+ + + + HI ++ Sbjct: 366 HPITQSTLVIKETRGSDTGTYTCRARNMMGARDYHVDLIVQGNQSKSQKHRTHIPVAIVV 425 Query: 207 GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILAD 266 PE+ G+ V+ C G P P + W R GG MP+ V +G L + N+ + Sbjct: 426 RPENQTELEGNEVSLNCNASGIPAPSITWYRQ-DGGYMPVNHRVV--NGDLIISNITKSL 482 Query: 267 EGEYSCEAENSVGAVSASGYLTVYDPPSI-NLSPNSVNVESGNVARFTCTATGRPEPTMF 325 EG Y CEA+N +GA + + V P + +L + + + A CT+TG P P + Sbjct: 483 EGTYVCEAKNVLGARTKEATVLVNIAPRLTSLHKTPLTIVENSTAVVPCTSTGFPTPEIS 542 Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385 WS GN +SR Y + A L I D +D R T VCSA N G V G Sbjct: 543 WSKIGNSM----DVSRMSYDSQA-------LIIKDVRYSD-RGTYVCSATNEEGR--VNG 588 Query: 386 KLT----VTSDDDRPPPIITNG--PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI 439 +T V + P I G P+++ L ++ VF P P I W G AL Sbjct: 589 TVTVIVQVAPRVHQQPKAIEFGYRPASKELQLR---VFG-----FPPPNITW--SGPALR 638 Query: 440 QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485 + R +DG+L++ + DSG Y + + G+ V L+V+ Sbjct: 639 HSKSRVNQSDGSLMIMRTEFRDSGEYQAIVKNVVGQAVIRTFLVVN 684 Score = 103 bits (247), Expect = 3e-20 Identities = 115/397 (28%), Positives = 161/397 (40%), Gaps = 42/397 (10%) Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK--GGVLVVSDTHRSILPAGGLFFLRA 71 I+ +P + T +LNC A G P+P+I WY+ GG + V+ HR + G L Sbjct: 423 IVVRPENQTELEGNEVSLNCNASGIPAPSITWYRQDGGYMPVN--HRVV--NGDLIISNI 478 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131 T S G Y CEA N G AR++ AT+ V + L + T V+ C Sbjct: 479 T----KSLEGTYVCEAKNVLG-ARTKEATVLVNIAPRLTSLHKTPLTIVENSTAVVPC-T 532 Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191 G P P + W K G ++ SRM D L+I+D R +D G Y C A N G R + Sbjct: 533 STGFPTPEISWSKIGNSM---DVSRMS-YDSQALIIKDVRYSDRGTYVCSATNEEG-RVN 587 Query: 192 AIATLKIHIKPYLITGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250 T+ + + P + P+ + +S Q RV G P P++ W S RV Sbjct: 588 GTVTVIVQVAPRVHQQPKAIEFGYRPASKELQLRVFGFPPPNITW--SGPALRHSKSRVN 645 Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV-----YDPPSINLSPNSVNVE 305 DGSL + D GEY +N VG +L V + I+L V Sbjct: 646 -QSDGSLMIMRTEFRDSGEYQAIVKNVVGQAVIRTFLVVNQGDFFKVFIIDLGQQLVRHS 704 Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFP----GMSRDKYHATAVFDGV-------- 353 G PT ++ N T + P G + T + + + Sbjct: 705 WGMFPLLLVAPLLMSFPTTPLTIVENSTAVVPCISTGFPAPVINWTKIENSMDPSRMSYD 764 Query: 354 -TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389 LTI D +D T VCSA N AG V G +TV Sbjct: 765 SRALTIKDVRLSDV-GTYVCSATNVAGQ--VNGNVTV 798 Score = 88.6 bits (210), Expect = 9e-16 Identities = 102/424 (24%), Positives = 170/424 (40%), Gaps = 39/424 (9%) Query: 78 SDAGVYWCEATNSYGTARSRNATL-----------HVAVLREEFRLEPESKQSAQGDTVV 126 SD G Y C A N G AR + L H + + PE++ +G+ V Sbjct: 381 SDTGTYTCRARNMMG-ARDYHVDLIVQGNQSKSQKHRTHIPVAIVVRPENQTELEGNEVS 439 Query: 127 LECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 L C G P P++ W +++G + + H V G+L+I + ++ G Y C A+N Sbjct: 440 LNC-NASGIPAPSITWYRQDGGYMPVN-----HRVVNGDLIISNITKSLEGTYVCEAKNV 493 Query: 186 AGTRESAIATLKIHIKPYLIT-GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 G R AT+ ++I P L + + S+ C G P P++ W S G +M Sbjct: 494 LGARTKE-ATVLVNIAPRLTSLHKTPLTIVENSTAVVPCTSTGFPTPEISW--SKIGNSM 550 Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304 + R+ D +L + +V +D G Y C A N G V+ + + V P ++ P ++ Sbjct: 551 DVSRMS-YDSQALIIKDVRYSDRGTYVCSATNEEGRVNGTVTVIVQVAPRVHQQPKAIEF 609 Query: 305 ESGNVAR-FTCTATGRPEPTMFWSVEGNR------------TIIFPGMSRDKYHATAVFD 351 ++ G P P + WS R +I RD A+ Sbjct: 610 GYRPASKELQLRVFGFPPPNITWSGPALRHSKSRVNQSDGSLMIMRTEFRDSGEYQAIVK 669 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411 V + T ++ + G VR + P +++ + T+ Sbjct: 670 NVVGQAVIRTFLVVNQGDFFKVFIIDLGQQLVRHSWGMFPLLLVAPLLMSFPTTPLTIVE 729 Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471 S AV PC + P P+I W ++ + R + L +KD+ SD GTY C A++ Sbjct: 730 NSTAVVPCISTGFPAPVINWTKIENSM--DPSRMSYDSRALTIKDVRLSDVGTYVCSATN 787 Query: 472 RHGK 475 G+ Sbjct: 788 VAGQ 791 >UniRef50_O15146 Cluster: Muscle, skeletal receptor tyrosine protein kinase precursor; n=53; Euteleostomi|Rep: Muscle, skeletal receptor tyrosine protein kinase precursor - Homo sapiens (Human) Length = 869 Score = 112 bits (269), Expect = 6e-23 Identities = 81/275 (29%), Positives = 129/275 (46%), Gaps = 16/275 (5%) Query: 10 EAPYIIEQPLDVTVAR-HQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLF 67 +AP +I PL+ A + AT C P P I W + +L+ + DT SI G L Sbjct: 26 KAP-VITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLL 84 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127 + + SD G+Y C A N G A L V ++ + P + + +G VL Sbjct: 85 TILSVED---SDDGIYCCTANNGVGGAVESCGALQVK-MKPKITRPPINVKIIEGLKAVL 140 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 C G+P+P+V W K L +SR+ +++ G+L I + ++ DAG+Y+C+A+N+ G Sbjct: 141 PCTT-MGNPKPSVSWIKGDSPLR--ENSRIAVLESGSLRIHNVQKEDAGQYRCVAKNSLG 197 Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247 T S + L++ + ++ PE GS VT C G P+P + W + + Sbjct: 198 TAYSKVVKLEVEVFARILRAPESHNVTFGSFVTLHCTATGIPVPTITWIENGNAVSSGSI 257 Query: 248 RVKVLD---DGSLRLDNVILADEGEYSCEAENSVG 279 + V D D L+L + G Y+C A N G Sbjct: 258 QESVKDRVIDSRLQL---FITKPGLYTCIATNKHG 289 Score = 91.5 bits (217), Expect = 1e-16 Identities = 77/284 (27%), Positives = 122/284 (42%), Gaps = 17/284 (5%) Query: 195 TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254 T K+ P + T E V A TF C V P P++ W R+ + R + ++ Sbjct: 21 TEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIREN 80 Query: 255 GSL-RLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSPNSVNVESGNVARF 312 G L + +V +D+G Y C A N VG AV + G L V P I P +V + G A Sbjct: 81 GQLLTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMKPKITRPPINVKIIEGLKAVL 140 Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372 CT G P+P++ W ++G+ + R+ + G L I++ K D+ C Sbjct: 141 PCTTMGNPKPSVSW-IKGDSPL------RENSRIAVLESG--SLRIHNVQKEDA-GQYRC 190 Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432 A N G+++ + V + I P + + S CTA P P I W Sbjct: 191 VAKNSLGTAYSK----VVKLEVEVFARILRAPESHNVTFGSFVTLHCTATGIPVPTITWI 246 Query: 433 FEGEALIQNHRRNVTNDGTLVLK-DLDKSDSGTYTCVASSRHGK 475 G A+ + D + + L + G YTC+A+++HG+ Sbjct: 247 ENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGE 290 Score = 68.1 bits (159), Expect = 1e-09 Identities = 67/258 (25%), Positives = 109/258 (42%), Gaps = 19/258 (7%) Query: 281 VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340 V+ SG + P I +V+ VA F C P+P + W+ R I + Sbjct: 16 VAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEISWT----RNKILIKLF 71 Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR-GKLTVTSDDDRPPPI 399 +Y +T+L++ D+D C+A N G + G L V + P Sbjct: 72 DTRYSIRENGQLLTILSVEDSDDG----IYCCTANNGVGGAVESCGALQV-----KMKPK 122 Query: 400 ITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDK 459 IT P N + AV PCT + P+P ++W L +N R V G+L + ++ K Sbjct: 123 ITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVLESGSLRIHNVQK 182 Query: 460 SDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTS 519 D+G Y CVA + G +S + ++ + I RA + ++ + T Sbjct: 183 EDAGQYRCVAKNSLGT-AYSKVVKLEVEVFARI--LRAPESHNVTFGSFVTLHCTATGIP 239 Query: 520 V-TLSWSQN-NKIGSSSI 535 V T++W +N N + S SI Sbjct: 240 VPTITWIENGNAVSSGSI 257 >UniRef50_Q13332 Cluster: Receptor-type tyrosine-protein phosphatase S precursor; n=34; Craniata|Rep: Receptor-type tyrosine-protein phosphatase S precursor - Homo sapiens (Human) Length = 1948 Score = 111 bits (268), Expect = 8e-23 Identities = 159/625 (25%), Positives = 236/625 (37%), Gaps = 80/625 (12%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI-LPAGGLFF 68 E P I++P D A+ C+A G P P + W K G V S +I Sbjct: 31 EPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAV 90 Query: 69 LRATHGRVHSDAGVYWCEATNSYG--TARSRNATLHVAVLREEFR---LEPESKQSAQGD 123 LR R D VY C A NS G T ++ L L F + P+ K + Sbjct: 91 LRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTR 150 Query: 124 TVVLECLPPRGSPEPNVYWKK----------NGQTLLFDGDSRMHLVDGGNLVIQDARQT 173 T + C G+P+P + W K NG+ ++ G L I+ + +T Sbjct: 151 TATMLCAAS-GNPDPEITWFKDFLPVDPSASNGRIKQLRSETFESTPIRGALQIESSEET 209 Query: 174 DAGRYQCIARNAAGTRESAIATLKI-------HIKPYLITGPEDVVAQTGSSVTFQCRVG 226 D G+Y+C+A N+AG R S+ A L + + P P G +V C Sbjct: 210 DQGKYECVATNSAGVRYSSPANLYVRELREVRRVAPRFSILPMSHEIMPGGNVNITCVAV 269 Query: 227 GDPLPDVLWRRSAGG----GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVS 282 G P+P V W + A +MP+GR L L +V D Y+C A +S+G + Sbjct: 270 GSPMPYVKWMQGAEDLTPEDDMPVGR------NVLELTDV--KDSANYTCVAMSSLGVIE 321 Query: 283 ASGYLTVYDPPSINLSPNSVNVESGNVARFTCT-ATGRPEPTMFWSVEGNRTIIFPGMSR 341 A +TV P +P + V T T +G P+P ++ +E + S+ Sbjct: 322 AVAQITVKSLPK---APGTPMVTENTATSITITWDSGNPDPVSYYVIE------YKSKSQ 372 Query: 342 DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401 D + T +I N S I SAVN G + VT ++ P Sbjct: 373 DGPYQIKEDITTTRYSIGGLSPN-SEYEIWVSAVNSIGQG-PPSESVVTRTGEQAPASAP 430 Query: 402 NGPSNQTLPIKSMAVFPCTAICTPEPIIAWY-----FEGEALIQNHRRNVTNDGTLVLKD 456 + L +M V P +I Y E E + N +++ +D L Sbjct: 431 RNVQARMLSATTMIV-QWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVG 489 Query: 457 LDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVT 516 D TYT V + + D P++ I + +PG P + Sbjct: 490 SLLEDE-TYTV--------RVLAFTSVGDGPLSDPI---QVKTQQGVPGQPMNLRAEARS 537 Query: 517 DTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKS 576 +TS+TLSWS + SI+ Y E+ RE G R T YVV+ Sbjct: 538 ETSITLSWSPPRQ---ESIIKY--ELLFREGDHGREVGRTFD---------PTTSYVVED 583 Query: 577 LIPGITYMFIVRTENSHGLSGPSPV 601 L P Y F + + GL +PV Sbjct: 584 LKPNTEYAFRLAARSPQGLGAFTPV 608 Score = 107 bits (258), Expect = 1e-21 Identities = 157/642 (24%), Positives = 248/642 (38%), Gaps = 83/642 (12%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LR 258 P I P+D + +G +F C+ GDP P V W + N D+ + LR Sbjct: 33 PRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLR 92 Query: 259 LDNVILA-DEGEYSCEAENSVGAVSASGYLTVYDP-------PSINLSPNSVNVESGNVA 310 + + DE Y C A+NSVG ++ LTV P+I++ P VE A Sbjct: 93 IQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTA 152 Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV---LTINDTDKNDSR 367 C A+G P+P + W + R K + F+ + L I +++ D + Sbjct: 153 TMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSETFESTPIRGALQIESSEETD-Q 211 Query: 368 NTIVCSAVNYAG---SSFVRGKLTVTSDDDRPPPIITNGP-SNQTLPIKSMAVFPCTAIC 423 C A N AG SS + + R P + P S++ +P ++ + C A+ Sbjct: 212 GKYECVATNSAGVRYSSPANLYVRELREVRRVAPRFSILPMSHEIMPGGNVNI-TCVAVG 270 Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483 +P P + W E L V G VL+ D DS YTCVA S G Sbjct: 271 SPMPYVKWMQGAEDLTPEDDMPV---GRNVLELTDVKDSANYTCVAMSSLGV-------- 319 Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543 I V SLP P P+ T TS+T++W N + Y +E Sbjct: 320 --------IEAVAQITVKSLPKAPGTPMVTENTATSITITWDSGNP---DPVSYYVIEYK 368 Query: 544 SRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603 S+ + G I + T Y + L P Y V NS G GP S Sbjct: 369 SK----------SQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIG-QGPPSESV 417 Query: 604 SVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEG 663 G+ + + + + R T IV+ E P++ + + + +Y +E Sbjct: 418 VTRTGEQAPA-----SAPRNVQARMLSATTMIVQWEE--PVEPNGLIRGYRV--YYTMEP 468 Query: 664 LFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRV 723 P+ N ++ + +D + SL + Y ++ F +G S+ Sbjct: 469 E----HPVGN----WQKHNV---DDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQ 517 Query: 724 AQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMV 783 +T VP G P+N+ + T++ L WSPP Q II Y ++ D Sbjct: 518 VKTQQGVP-GQPMNLRAEARSETSITLSWSPPR---QESIIK-YELLFREGDHGRE---- 568 Query: 784 AINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825 + T TS ++ +L Y+ ++AA + GLG F+ V Sbjct: 569 -VGRTFDPTTSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVV 609 Score = 54.4 bits (125), Expect = 2e-05 Identities = 39/140 (27%), Positives = 65/140 (46%), Gaps = 10/140 (7%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753 + +L K+T+Y + + G S+ V +T +DVP PP +E LN T + + W Sbjct: 683 LEALEKWTQYRITTVAHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWR 742 Query: 754 PPELQLQNGIITGYNVVVNWLD------VPANKSMVAIN----TTVHQATSLIMTNLTSG 803 P Q+G I GY V ++ P K ++ + T +++TNL Sbjct: 743 SPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQWETDDTAEYEMVITNLQPE 802 Query: 804 VSYSVQIAAETIIGLGPFSQ 823 +YS+ +AA T+ G G S+ Sbjct: 803 TAYSITVAAYTMKGDGARSK 822 Score = 53.2 bits (122), Expect = 4e-05 Identities = 46/187 (24%), Positives = 78/187 (41%), Gaps = 10/187 (5%) Query: 670 PLDNITIEYEMKT------ILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRV 723 P+ IEY+ K+ I + + I L ++YE ++ +G PS S V Sbjct: 359 PVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVV 418 Query: 724 AQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMV 783 +T + P P N++ +L+ TT+ ++W P NG+I GY V + P + Sbjct: 419 TRTGEQAPASAPRNVQARMLSATTMIVQWEEP--VEPNGLIRGYRVY--YTMEPEHPVGN 474 Query: 784 AINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYP 843 V + + +L +Y+V++ A T +G GP S + G + R Sbjct: 475 WQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAE 534 Query: 844 MNGEVSI 850 E SI Sbjct: 535 ARSETSI 541 Score = 52.0 bits (119), Expect = 1e-04 Identities = 36/143 (25%), Positives = 61/143 (42%), Gaps = 5/143 (3%) Query: 690 SGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVH 749 + + + L+ T+Y F L + G + +TL P PP +++ + +T + Sbjct: 577 TSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAIL 636 Query: 750 LKWSPPELQLQNGIITGYNVVVNWL--DVPANKSMVAINTTVHQATSLIMTNLTSGVSYS 807 + W PP + NG + GY+V L + P K + I T T +++ L Y Sbjct: 637 VSWRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPT---TTQILLEALEKWTQYR 693 Query: 808 VQIAAETIIGLGPFSQKVYFNID 830 + A T +G GP S V D Sbjct: 694 ITTVAHTEVGPGPESSPVVVRTD 716 Score = 45.6 bits (103), Expect = 0.008 Identities = 39/136 (28%), Positives = 60/136 (44%), Gaps = 9/136 (6%) Query: 728 DDVPDGPPINIEMF-ILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDV--PANKSMVA 784 +D P G P +E + TV L+W PP +NG I Y V V PA ++ + Sbjct: 925 EDTPRGHPQILEAAGNASAGTVLLRWLPPVPAERNGAIVKYTVAVREAGALGPARETELP 984 Query: 785 INTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPM 844 +L + L +Y +Q+ A T G GPFS V + R+ D +S P Sbjct: 985 AAAEPGAENALTLQGLKPDTAYDLQVRAHTRRGPGPFSPPVRY----RTFLRDQVS--PK 1038 Query: 845 NGEVSIVAGDFVMETW 860 N +V ++ V+ +W Sbjct: 1039 NFKVKMIMKTSVLLSW 1054 >UniRef50_Q15746 Cluster: Myosin light chain kinase, smooth muscle; n=40; Theria|Rep: Myosin light chain kinase, smooth muscle - Homo sapiens (Human) Length = 1914 Score = 111 bits (268), Expect = 8e-23 Identities = 104/353 (29%), Positives = 140/353 (39%), Gaps = 42/353 (11%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLR 70 P +P V +Q C G P P + W+ G V + + G +L Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHV---AVLREEFRLEPESKQSA--QGDTV 125 R D+G Y C A+N+ G S + TL V AV+ K A +G Sbjct: 474 LLKARTR-DSGTYSCTASNAQGQV-SCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDF 531 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARN 184 VL+C RG+P P + W NGQ + + +R G L IQDA D G Y C+A N Sbjct: 532 VLQC-SVRGTPVPRITWLLNGQPIQY---ARSTCEAGVAELHIQDALPEDHGTYTCLAEN 587 Query: 185 AAGTRESAIATLKIHIK-------------------PYLITGPEDVVAQTGSSVTFQCRV 225 A G + S A + +H K P + G D+ GS VT +V Sbjct: 588 ALG-QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQV 646 Query: 226 GGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVS 282 G+P P+V+W + G G SL + V D G Y+CEA NS G V Sbjct: 647 SGNPPPEVIWLHN-GNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVR 705 Query: 283 ASGYLTVYDP-----PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330 LTV +P P P SV G +C G P PT+ W +G Sbjct: 706 TQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDG 758 Score = 104 bits (249), Expect = 2e-20 Identities = 103/400 (25%), Positives = 163/400 (40%), Gaps = 45/400 (11%) Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LV 166 +F +P+S++ + TV C G P+P V W G + S D G+ L Sbjct: 415 KFESKPQSQEVKENQTVKFRC-EVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATLKIH------IKPYLITGPEDVVAQTGSSVT 220 + AR D+G Y C A NA G + S TL++ + P + +D G Sbjct: 474 LLKARTRDSGTYSCTASNAQG-QVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFV 532 Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSV 278 QC V G P+P + W + G + R + G L + + + D G Y+C AEN++ Sbjct: 533 LQCSVRGTPVPRITWLLN--GQPIQYAR-STCEAGVAELHIQDALPEDHGTYTCLAENAL 589 Query: 279 GAVSASGYLTVYD-------------PPSINLSP------NSVNVESGNVARFTCTATGR 319 G VS S ++TV++ PS +P + + V G+ T +G Sbjct: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649 Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379 P P + W GN + +H + L I + D+ T C A N AG Sbjct: 650 PPPEVIWLHNGNEI-----QESEDFHFEQRGTQHS-LWIQEVFPEDT-GTYTCEAWNSAG 702 Query: 380 SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI 439 + LTV D P + P + T + + C P P + W +G+AL Sbjct: 703 EVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALC 762 Query: 440 QN--HRRNVTNDG--TLVLKDLDKSDSGTYTCVASSRHGK 475 ++ H + N+ TLVLK + +G Y + +R G+ Sbjct: 763 KDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802 Score = 78.2 bits (184), Expect = 1e-12 Identities = 88/289 (30%), Positives = 116/289 (40%), Gaps = 32/289 (11%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 D V Q L C G+P P I W G + RS AG + D Sbjct: 522 DCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI--QYARSTCEAGVAEL--HIQDALPED 577 Query: 80 AGVYWCEATNSYGTAR-SRNATLHV--AVLREEFRLE-PESKQSA----QG--DTVVLE- 128 G Y C A N+ G S T+H + + E+ L SK +A QG D V++ Sbjct: 578 HGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDG 637 Query: 129 -----CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG---NLVIQDARQTDAGRYQC 180 + G+P P V W NG + D H G +L IQ+ D G Y C Sbjct: 638 SQVTMTVQVSGNPPPEVIWLHNGNEIQESED--FHFEQRGTQHSLWIQEVFPEDTGTYTC 695 Query: 181 IARNAAG-TRESAIATLKI-H--IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 A N+AG R A+ T++ H +P+ I+ P V A G SV C + GDP P V W Sbjct: 696 EAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWL 755 Query: 237 RSAGGGNMPLGRVKVL---DDGSLRLDNVILADEGEYSCEAENSVGAVS 282 R G +VL D +L L V G+Y +N VG S Sbjct: 756 RDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804 Score = 68.5 bits (160), Expect = 1e-09 Identities = 78/312 (25%), Positives = 113/312 (36%), Gaps = 36/312 (11%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GS--LR 258 P + P+ + +V F+C V G P P+V W G ++V +D GS L Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN------SVNVESGNVARF 312 L D G YSC A N+ G VS S L V + ++P+ V G Sbjct: 474 LLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533 Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372 C+ G P P + W + G +Y + GV L I D D T C Sbjct: 534 QCSVRGTPVPRITWLLNGQPI---------QYARSTCEAGVAELHIQDALPED-HGTYTC 583 Query: 373 SAVNYAGSSFVRGKLTV--TSDDDRPPPIITNGPSNQTLPI------------KSMAVFP 418 A N G +TV + ++ PS T PI S Sbjct: 584 LAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT 643 Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHGK 475 P P + W G + ++ + GT L ++++ D+GTYTC A + G+ Sbjct: 644 VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGE 703 Query: 476 YVWSGALLVDSP 487 L V P Sbjct: 704 VRTQAVLTVQEP 715 Score = 56.0 bits (129), Expect = 6e-06 Identities = 47/183 (25%), Positives = 76/183 (41%), Gaps = 9/183 (4%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 AP ++ D+ V T+ + G+P P + W G + G L Sbjct: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLW 681 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE----FRLEPESKQSAQGDTVV 126 D G Y CEA NS G R++ A L V + F +P S ++ G +V+ Sbjct: 682 IQEV-FPEDTGTYTCEAWNSAGEVRTQ-AVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 739 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGD--SRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 + C G P P V+W ++G+ L D + D LV++ + AG+Y+ + +N Sbjct: 740 ISC-AIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 798 Query: 185 AAG 187 G Sbjct: 799 RVG 801 Score = 54.8 bits (126), Expect = 1e-05 Identities = 43/169 (25%), Positives = 76/169 (44%), Gaps = 12/169 (7%) Query: 457 LDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVT 516 ++ S++G+ + ++R ++ LLV++ + V P P ++ Sbjct: 1286 VENSENGSKLTILAARQ-EHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIR 1344 Query: 517 DTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKS 576 +S+TLSW ++ G S++ Y +E++ S N T W +A T + V+ Sbjct: 1345 SSSLTLSWYGSSYDGGSAVQSYSIEIWD----SANKT------WKELAT-CRSTSFNVQD 1393 Query: 577 LIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTE 625 L+P Y F VR N +G S PS S+ TVG+ + VS+ E Sbjct: 1394 LLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDE 1442 Score = 52.8 bits (121), Expect = 5e-05 Identities = 31/101 (30%), Positives = 52/101 (51%), Gaps = 3/101 (2%) Query: 192 AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW-RRSAGGGNMPLGRVK 250 A+A K H+KPY D+ GS+ F C++ G P P+V+W + ++ Sbjct: 1799 AVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID 1858 Query: 251 VLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 +DG SL + +V D+ +Y+C+A NS+G + + L V Sbjct: 1859 YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899 Score = 48.8 bits (111), Expect = 9e-04 Identities = 35/114 (30%), Positives = 55/114 (48%), Gaps = 7/114 (6%) Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 I++ + S + ++ + P I P ++ + G++ F+ RV G P P V W R+ Sbjct: 12 ISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRN-- 69 Query: 241 GGNMPLGRVKVLDDG-----SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 G + G +LD G SL + V D G+Y+CEA N GA + LTV Sbjct: 70 GQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123 Score = 46.0 bits (104), Expect = 0.006 Identities = 29/86 (33%), Positives = 40/86 (46%), Gaps = 3/86 (3%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVI 167 F L P + +G T E RG PEP V W +NGQ + G + G +LVI Sbjct: 35 FILPPRNLCIKEGATAKFEGRV-RGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVI 93 Query: 168 QDARQTDAGRYQCIARNAAGTRESAI 193 + D G+Y C A N +G R+ + Sbjct: 94 HAVHEEDRGKYTCEATNGSGARQVTV 119 Score = 45.6 bits (103), Expect = 0.008 Identities = 31/96 (32%), Positives = 39/96 (40%), Gaps = 3/96 (3%) Query: 9 GEAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67 GE P L V V Q +C+ G P P + W KG V + S+ G+ Sbjct: 157 GECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQ 216 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103 L HG D GVY C N G A S +A L + Sbjct: 217 VLE-IHGVNQDDVGVYTCLVVNGSGKA-SMSAELSI 250 Score = 45.2 bits (102), Expect = 0.011 Identities = 32/98 (32%), Positives = 43/98 (43%), Gaps = 7/98 (7%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG--GLF 67 EAP I P ++ + A R G P P + W++ G + S R +L G G F Sbjct: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSG-GRFLLDCGIRGTF 89 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV 105 L H D G Y CEATN G +R T+ + V Sbjct: 90 SL-VIHAVHEEDRGKYTCEATNGSG---ARQVTVELTV 123 Score = 45.2 bits (102), Expect = 0.011 Identities = 31/116 (26%), Positives = 50/116 (43%), Gaps = 6/116 (5%) Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242 R AGT ++ + P +DV G + QC+V DP ++W + G Sbjct: 1079 RGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIW--TLNGK 1136 Query: 243 NMPLGRVKVLD-DGSL---RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294 + + +L +GSL ++ + D G Y C A+N G S +TV D P+ Sbjct: 1137 TLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192 Score = 42.3 bits (95), Expect = 0.078 Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 7/102 (6%) Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 PP V V+ G + RF+C TGRP+P + W ++GN P + + + + Sbjct: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTW-LKGN----VP-LQPSARVSVSEKN 213 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393 G+ VL I+ +++D C VN +G + + +L++ D Sbjct: 214 GMQVLEIHGVNQDDV-GVYTCLVVNGSGKASMSAELSIQGLD 254 Score = 42.3 bits (95), Expect = 0.078 Identities = 31/94 (32%), Positives = 41/94 (43%), Gaps = 10/94 (10%) Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGS---LRLDNVIL 264 VV + G F C++ G P P V W + GN+PL RV V + L + V Sbjct: 170 VVVKEGQMGRFSCKITGRPQPQVTWLK----GNVPLQPSARVSVSEKNGMQVLEIHGVNQ 225 Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298 D G Y+C N G S S L++ S N S Sbjct: 226 DDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259 Score = 41.1 bits (92), Expect = 0.18 Identities = 19/62 (30%), Positives = 29/62 (46%), Gaps = 1/62 (1%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT-HRSILPAGGLF 67 G P+ I +P VT + Q ++C G P P + W + G + DT H +L +F Sbjct: 718 GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF 777 Query: 68 FL 69 L Sbjct: 778 TL 779 Score = 40.7 bits (91), Expect = 0.24 Identities = 29/104 (27%), Positives = 43/104 (41%), Gaps = 4/104 (3%) Query: 386 KLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRR 444 ++ + D P + P +Q + F C P+P +AW+ EG + Q Sbjct: 402 RIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSI 461 Query: 445 NVTNDG---TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485 V D L L DSGTY+C AS+ G+ S L V+ Sbjct: 462 EVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVE 505 Score = 37.5 bits (83), Expect = 2.2 Identities = 27/99 (27%), Positives = 42/99 (42%), Gaps = 6/99 (6%) Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350 + P+ L P ++ ++ G A+F G PEP + W G P S ++ Sbjct: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQ-----PITSGGRFLLDCGI 85 Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389 G L I+ + D R C A N +G+ V +LTV Sbjct: 86 RGTFSLVIHAVHEED-RGKYTCEATNGSGARQVTVELTV 123 Score = 36.7 bits (81), Expect = 3.9 Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 6/84 (7%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV--- 166 F+ + + A+G ++L+C P + W NG+TL + L G+L Sbjct: 1100 FKQKLQDVHVAEGKKLLLQC-QVSSDPPATIIWTLNGKTL--KTTKFIILSQEGSLCSVS 1156 Query: 167 IQDARQTDAGRYQCIARNAAGTRE 190 I+ A D G Y+C+A+N AG E Sbjct: 1157 IEKALPEDRGLYKCVAKNDAGQAE 1180 Score = 35.5 bits (78), Expect = 8.9 Identities = 32/112 (28%), Positives = 43/112 (38%), Gaps = 3/112 (2%) Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66 + G AP ++ DV VA + L C+ P I W G + T IL G Sbjct: 1093 SQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGS 1151 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESK 117 + + D G+Y C A N G A S T+ A E + PE K Sbjct: 1152 LCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTK-APEMK 1202 >UniRef50_Q96JA1 Cluster: Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor; n=22; Euteleostomi|Rep: Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor - Homo sapiens (Human) Length = 1093 Score = 111 bits (268), Expect = 8e-23 Identities = 82/298 (27%), Positives = 132/298 (44%), Gaps = 24/298 (8%) Query: 106 LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVY-WKKNGQTLL---FDGDSRMHLVD 161 L+ + +PE+ + G + C S P + WKK+ + L + +H D Sbjct: 493 LKPQIITQPETTMAMVGKDIRFTCSAASSSSSPMTFAWKKDNEVLTNADMENFVHVHAQD 552 Query: 162 GGNL---VIQDARQTD---AGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT 215 G + I RQ GRYQC+ N G+ S A L +++ P P D+ +T Sbjct: 553 GEVMEYTTILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVNVLPSFTKTPHDITIRT 612 Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL----DDGSLRLDNVILADEGEYS 271 + +C G P P + W++ GG + P R + + DD + +V + D G YS Sbjct: 613 TTMARLECAATGHPNPQIAWQKD-GGTDFPAARERRMHVMPDDDVFFITDVKIDDAGVYS 671 Query: 272 CEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGN 331 C A+NS G++SA+ LTV + PS+ + V G C ATG P P + W +G+ Sbjct: 672 CTAQNSAGSISANATLTVLETPSLVVPLEDRVVSVGETVALQCKATGNPPPRITW-FKGD 730 Query: 332 RTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389 R P +++H T D ++ N ++ R T C N G+ +L+V Sbjct: 731 R----PLSLTERHHLTP--DNQLLVVQNVVAEDAGRYT--CEMSNTLGTERAHSQLSV 780 Score = 94.3 bits (224), Expect = 2e-17 Identities = 78/289 (26%), Positives = 111/289 (38%), Gaps = 25/289 (8%) Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL--WRRS---AGGGNMPLGRVKVLDD 254 +KP +IT PE +A G + F C + W++ +M D Sbjct: 493 LKPQIITQPETTMAMVGKDIRFTCSAASSSSSPMTFAWKKDNEVLTNADMENFVHVHAQD 552 Query: 255 GS-------LRLDNVILADEGEYSCEAENSVGAV-SASGYLTVYDPPSINLSPNSVNVES 306 G L L V EG Y C N G+ S LTV PS +P+ + + + Sbjct: 553 GEVMEYTTILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVNVLPSFTKTPHDITIRT 612 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 +AR C ATG P P + W +G FP + H D V I D K D Sbjct: 613 TTMARLECAATGHPNPQIAWQKDGGTD--FPAARERRMHVMPDDD---VFFITDV-KIDD 666 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426 C+A N AGS LTV P+ ++ + + C A P Sbjct: 667 AGVYSCTAQNSAGSISANATLTVLETPSLVVPL-----EDRVVSVGETVALQCKATGNPP 721 Query: 427 PIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474 P I W+ L R ++T D LV++++ D+G YTC S+ G Sbjct: 722 PRITWFKGDRPLSLTERHHLTPDNQLLVVQNVVAEDAGRYTCEMSNTLG 770 Score = 89.4 bits (212), Expect = 5e-16 Identities = 66/191 (34%), Positives = 90/191 (47%), Gaps = 14/191 (7%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG---VLVVSDTHRSILP 62 +T P + P D+T+ A L C A G P+P I W K G + ++P Sbjct: 593 LTVNVLPSFTKTPHDITIRTTTMARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMP 652 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQ 121 +FF+ T ++ DAGVY C A NS G+ S NATL VL + P E + + Sbjct: 653 DDDVFFI--TDVKI-DDAGVYSCTAQNSAGSI-SANATL--TVLETPSLVVPLEDRVVSV 706 Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQC 180 G+TV L+C G+P P + W K + L R HL D LV+Q+ DAGRY C Sbjct: 707 GETVALQC-KATGNPPPRITWFKGDRPLSL--TERHHLTPDNQLLVVQNVVAEDAGRYTC 763 Query: 181 IARNAAGTRES 191 N GT + Sbjct: 764 EMSNTLGTERA 774 Score = 51.6 bits (118), Expect = 1e-04 Identities = 49/202 (24%), Positives = 81/202 (40%), Gaps = 17/202 (8%) Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA---- 348 P I P + G RFTC+A M ++ + + ++ + H A Sbjct: 495 PQIITQPETTMAMVGKDIRFTCSAASSSSSPMTFAWKKDNEVLTNADMENFVHVHAQDGE 554 Query: 349 VFDGVTVLTIND-TDKNDSRNTIVCSAVNYAGSSFV-RGKLTVTSDDDRPPPIITNGPSN 406 V + T+L + T ++ R C N+ GS++ + +LTV P T P + Sbjct: 555 VMEYTTILHLRQVTFGHEGRYQ--CVITNHFGSTYSHKARLTVNV-----LPSFTKTPHD 607 Query: 407 QTLPIKSMAVFPCTAICTPEPIIAWYFEG----EALIQNHRRNVTNDGTLVLKDLDKSDS 462 T+ +MA C A P P IAW +G A + + +D + D+ D+ Sbjct: 608 ITIRTTTMARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDDA 667 Query: 463 GTYTCVASSRHGKYVWSGALLV 484 G Y+C A + G + L V Sbjct: 668 GVYSCTAQNSAGSISANATLTV 689 Score = 48.8 bits (111), Expect = 9e-04 Identities = 29/90 (32%), Positives = 46/90 (51%), Gaps = 5/90 (5%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLFF 68 E P ++ D V+ + L C+A G+P P I W+KG L +++ H + P L Sbjct: 691 ETPSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHH-LTPDNQLLV 749 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRN 98 ++ V DAG Y CE +N+ GT R+ + Sbjct: 750 VQNV---VAEDAGRYTCEMSNTLGTERAHS 776 >UniRef50_Q4KMG0 Cluster: Cell adhesion molecule-related/down-regulated by oncogenes precursor; n=27; Tetrapoda|Rep: Cell adhesion molecule-related/down-regulated by oncogenes precursor - Homo sapiens (Human) Length = 1287 Score = 111 bits (268), Expect = 8e-23 Identities = 121/451 (26%), Positives = 174/451 (38%), Gaps = 31/451 (6%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 V+S APY +PL P L+C A + I W G + + + G Sbjct: 23 VSSDLAPYFTSEPLSAVQKLGGPVVLHCSAQ-PVTTRISWLHNGKTLDGNLEHIKIHQGT 81 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 L L + G Y C A NS G S AT+ VAVL + + + Sbjct: 82 LTILSLNSSLL----GYYQCLANNSIGAIVSGPATVSVAVLGDFGSSTKHVITAEEKSAG 137 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 + C P +P+ V +K G+ L ++ + ++ GNL I + D G Y+C A N Sbjct: 138 FIGCRVPESNPKAEVRYKIRGKWLEHSTENYL-ILPSGNLQILNVSLEDKGSYKCAAYNP 196 Query: 186 AG--TRESAIATLKIHIKP-----YLI--TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 + I + +P +++ T + + + S VT +C V G P P V W Sbjct: 197 VTHQLKVEPIGRKLLVSRPSSDDVHILHPTHSQALAVLSRSPVTLECVVSGVPAPQVYWL 256 Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT-VYDPPSI 295 + G P + L L D+V AD G YSC A N G V Y+ V + SI Sbjct: 257 KD-GQDIAPESNWRRLYS-HLATDSVDPADSGNYSCMAGNKSGDVKYVTYMVNVLEHASI 314 Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355 + V G FTC G P P W N I P H TA +G+ + Sbjct: 315 SKGLQDQIVSLGATVHFTCDVHGNPAPNCTWF--HNAQPIHPSAR----HLTAG-NGLKI 367 Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415 + D + C A N G G+L + +D P IIT P + + Sbjct: 368 SGVTVEDVGMYQ----CVADNGIGFMHSTGRLEIENDGGFKPVIIT-APVSAKVADGDFV 422 Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNV 446 C A P P+I WY + LI +H V Sbjct: 423 TLSCNASGLPVPVIRWY-DSHGLITSHPSQV 452 Score = 84.6 bits (200), Expect = 1e-14 Identities = 99/390 (25%), Positives = 154/390 (39%), Gaps = 34/390 (8%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169 F EP S G VVL C + + W NG+TL DG+ + G L I Sbjct: 31 FTSEPLSAVQKLGGPVVLHCSAQPVTTR--ISWLHNGKTL--DGNLEHIKIHQGTLTILS 86 Query: 170 ARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTF-QCRVG-G 227 + G YQC+A N+ G S AT+ + + + + V+ S F CRV Sbjct: 87 LNSSLLGYYQCLANNSIGAIVSGPATVSVAVLGDFGSSTKHVITAEEKSAGFIGCRVPES 146 Query: 228 DPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG---AVSAS 284 +P +V ++ +L G+L++ NV L D+G Y C A N V V Sbjct: 147 NPKAEVRYKIRGKWLEHSTENYLILPSGNLQILNVSLEDKGSYKCAAYNPVTHQLKVEPI 206 Query: 285 GYLTVYDPPSIN----LSP---NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337 G + PS + L P ++ V S + C +G P P ++W +G I P Sbjct: 207 GRKLLVSRPSSDDVHILHPTHSQALAVLSRSPVTLECVVSGVPAPQVYWLKDGQD--IAP 264 Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGS-SFVRGKLTVTSDDDRP 396 + + ++ D V D DS N C A N +G +V + V Sbjct: 265 ESNWRRLYSHLATDSV--------DPADSGN-YSCMAGNKSGDVKYVTYMVNVLEHAS-- 313 Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKD 456 I+ G +Q + + + F C P P W+ + I R++T L + Sbjct: 314 ---ISKGLQDQIVSLGATVHFTCDVHGNPAPNCTWFHNAQP-IHPSARHLTAGNGLKISG 369 Query: 457 LDKSDSGTYTCVASSRHGKYVWSGALLVDS 486 + D G Y CVA + G +G L +++ Sbjct: 370 VTVEDVGMYQCVADNGIGFMHSTGRLEIEN 399 Score = 42.3 bits (95), Expect = 0.078 Identities = 58/232 (25%), Positives = 93/232 (40%), Gaps = 32/232 (13%) Query: 501 SSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGW 560 S +P P +P ++TSV ++W G S I ++VE + R S W Sbjct: 718 SGVPEAPDRPTISTASETSVYVTWIPRAN-GGSPITAFKVE-YKRMRTSN---------W 766 Query: 561 VVIARRV--HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGT 618 +V A + + V+SL PG TY F V N +G S S S V Sbjct: 767 LVAAEDIPPSKLSVEVRSLEPGSTYKFRVIAINHYGESFRSSASRPYQV----------V 816 Query: 619 GVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEIL----NFYYLEGLFIYFRPLDNI 674 G N + + +T + EA + I L W + N ++G +IY+RP D+ Sbjct: 817 GFPN--RFSSRPITGPHIAYTEA--VSDTQIMLKWTYIPSSNNNTPIQGFYIYYRPTDSD 872 Query: 675 TIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQT 726 + + K + I L+ T Y+ + F + E + SN + +T Sbjct: 873 N-DSDYKRDVVEGSKQWHMIGHLQPETSYDIKMQCFNEGGESEFSNVMICET 923 >UniRef50_UPI0000546958 Cluster: PREDICTED: hypothetical protein; n=1; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 1563 Score = 111 bits (267), Expect = 1e-22 Identities = 119/497 (23%), Positives = 201/497 (40%), Gaps = 58/497 (11%) Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181 G ++ L+C +G+P P + W K+G + ++ +V+G +R+ AG+YQC Sbjct: 151 GRSLTLKCAA-QGNPRPTITWSKDGAPI--KPQHKVKMVNGSVSFHAVSREA-AGQYQCY 206 Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV--LWRRSA 239 N+ G + + LKI P +I P D V +C+ DP P++ +W+R Sbjct: 207 TSNSEGNA-THVTRLKIIGPPVIIIPPSDTVLNMSQDAKLKCQAEADP-PNMTYVWQRQG 264 Query: 240 GGG---NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSI 295 + R+KV+ DG+L + + D G Y+C N + + SAS LTV P + Sbjct: 265 VDIYHIDSLKSRIKVIVDGTLLISRLAPEDSGNYTCMPTNGLPVSPSASAVLTVQHPAQV 324 Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMF-WSVEGNRTII--FPGMSRDKYHATAVFDG 352 P + +G C P + W +G + +PG T DG Sbjct: 325 IQMPKLTFLPTGMRGAIVCPVRAEPPLSHIDWIKDGKPLDLGMYPGW-------TLASDG 377 Query: 353 -VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ-TLP 410 + + T+ND D+ +C+ N G++ TV D PP P N+ Sbjct: 378 SIVIATVND----DAAGVYICTPYNSFGTTGQSEPTTVILQD---PPSFKVSPRNEYRQD 430 Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470 + +M V PC + P P + W G A + +G+L+L L K G + C +S Sbjct: 431 VGTMLVIPCQMVGNPAPKVNWRKIGAA--TRSLFTLAGNGSLILHPLSKDHQGEWECSSS 488 Query: 471 SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530 +R +LV + + H + VS +PG +SW Sbjct: 489 NRVATVSIKTMVLV---LGTSPH--AVSSVSVIPG-----------TNQANVSWVAGFDG 532 Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590 G + V+ ++ +G + W+ + + +V +L+P Y F V + Sbjct: 533 GYTQTF----TVWYKQVSAGRTEEKQE--WLSFSDLSTENSLLVTNLLPATEYQFSVMAQ 586 Query: 591 NSHGLSGPSPVSDSVTV 607 N G P S+ +TV Sbjct: 587 NK---IGTGPFSEIITV 600 Score = 97.5 bits (232), Expect = 2e-18 Identities = 90/332 (27%), Positives = 126/332 (37%), Gaps = 19/332 (5%) Query: 12 PYIIE-QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 P + E P +V V + TL C A G+P P I W K G + H+ + G + F Sbjct: 136 PVLTETSPPEVEVFVGRSLTLKCAAQGNPRPTITWSKDGA-PIKPQHKVKMVNGSVSF-- 192 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130 H AG Y C +NS G A + T + + P L+C Sbjct: 193 --HAVSREAAGQYQCYTSNSEGNAT--HVTRLKIIGPPVIIIPPSDTVLNMSQDAKLKCQ 248 Query: 131 PPRGSPEPNVYWKKNGQTLL-FDG-DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188 P W++ G + D SR+ ++ G L+I D+G Y C+ N Sbjct: 249 AEADPPNMTYVWQRQGVDIYHIDSLKSRIKVIVDGTLLISRLAPEDSGNYTCMPTNGLPV 308 Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD-PLPDVLWRRSAGGGNMPLG 247 SA A L + +I P+ TG C V + PL + W + G + LG Sbjct: 309 SPSASAVLTVQHPAQVIQMPKLTFLPTGMRGAIVCPVRAEPPLSHIDWIKD--GKPLDLG 366 Query: 248 RV---KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV--YDPPSINLSP-NS 301 + DGS+ + V G Y C NS G S TV DPPS +SP N Sbjct: 367 MYPGWTLASDGSIVIATVNDDAAGVYICTPYNSFGTTGQSEPTTVILQDPPSFKVSPRNE 426 Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRT 333 + G + C G P P + W G T Sbjct: 427 YRQDVGTMLVIPCQMVGNPAPKVNWRKIGAAT 458 Score = 76.6 bits (180), Expect = 4e-12 Identities = 83/334 (24%), Positives = 127/334 (38%), Gaps = 24/334 (7%) Query: 152 DGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT-----LKIHIKPYLI- 205 D D R+ L G +L + + D G Y+C T E A ++ L + P L Sbjct: 81 DYDGRVSLFGGTSLQMSGLQLEDEGWYECRILPLDQTTEEAGSSGSWTRLSVTAPPVLTE 140 Query: 206 TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA 265 T P +V G S+T +C G+P P + W + G P +VK++ +GS+ V Sbjct: 141 TSPPEVEVFVGRSLTLKCAAQGNPRPTITWSKD-GAPIKPQHKVKMV-NGSVSFHAVSRE 198 Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA-TGRPEPTM 324 G+Y C NS G + L + PP I + P+ + A+ C A P T Sbjct: 199 AAGQYQCYTSNSEGNATHVTRLKIIGPPVIIIPPSDTVLNMSQDAKLKCQAEADPPNMTY 258 Query: 325 FWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR 384 W +G + + K + DG L I+ DS N S Sbjct: 259 VWQRQG---VDIYHIDSLKSRIKVIVDG--TLLISRLAPEDSGNYTCMPTNGLPVSPSAS 313 Query: 385 GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI--IAWYFEGEALIQNH 442 LTV + P + P LP C P P+ I W +G+ L Sbjct: 314 AVLTV-----QHPAQVIQMPKLTFLPTGMRGAIVCPVRAEP-PLSHIDWIKDGKPLDLGM 367 Query: 443 RRNVT--NDGTLVLKDLDKSDSGTYTCVASSRHG 474 T +DG++V+ ++ +G Y C + G Sbjct: 368 YPGWTLASDGSIVIATVNDDAAGVYICTPYNSFG 401 Score = 61.7 bits (143), Expect = 1e-07 Identities = 48/216 (22%), Positives = 87/216 (40%), Gaps = 10/216 (4%) Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139 AGVY C NS+GT T + F++ P ++ T+++ G+P P Sbjct: 389 AGVYICTPYNSFGTTGQSEPTTVILQDPPSFKVSPRNEYRQDVGTMLVIPCQMVGNPAPK 448 Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199 V W+K G S L G+L++ + G ++C + N T L + Sbjct: 449 VNWRKIGAAT----RSLFTLAGNGSLILHPLSKDHQGEWECSSSNRVATVSIKTMVLVLG 504 Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLWRRSAGGGNMP-----LGRVKVLD 253 P+ ++ + ++V++ GG +W + G L + Sbjct: 505 TSPHAVSSVSVIPGTNQANVSWVAGFDGGYTQTFTVWYKQVSAGRTEEKQEWLSFSDLST 564 Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 + SL + N++ A E ++S A+N +G S +TV Sbjct: 565 ENSLLVTNLLPATEYQFSVMAQNKIGTGPFSEIITV 600 >UniRef50_UPI0000DB7443 Cluster: PREDICTED: similar to Fasciclin 2 CG3665-PB, isoform B isoform 1; n=1; Apis mellifera|Rep: PREDICTED: similar to Fasciclin 2 CG3665-PB, isoform B isoform 1 - Apis mellifera Length = 741 Score = 111 bits (266), Expect = 1e-22 Identities = 107/407 (26%), Positives = 172/407 (42%), Gaps = 23/407 (5%) Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139 AG Y C+AT + ++ T+ ++ + P ++ G+ ++C R P P+ Sbjct: 89 AGKYTCKATYANSIQLQKSVTIDT-IVAITWDNAPLNQYPILGEDFAIQC-KVRARPSPS 146 Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN-AAGTRESAIATLKI 198 V W NG+ L+ D +++D L I++ +++D G Y C A + G + +++ Sbjct: 147 VDWLYNGE-LIKTNDH--YIIDTYALKIKNVQESDDGVYTCRASVFSTGELKERPIRVEV 203 Query: 199 HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP-LGRVKV-LDDGS 256 HI+P + P + G + +C G P P W +S N+ + R V D G Sbjct: 204 HIRPTVSEMPNPINMIEGKDASIKCEARGKPPPKFTWVKSLTHQNLSNVDRFSVDPDTGV 263 Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316 L + NV D GEY C A N G + + + V P I NS VE A C A Sbjct: 264 LTITNVNRDDAGEYQCTATNLAGTANTNIMVNVIVKPKIIEFLNSTVVEDKE-ATLVCKA 322 Query: 317 TGRPEPTM-FWSVEGNRTIIF-PGMSRDKYHA-TAVFDGVTVLTINDTDKNDSRNTIV-C 372 GRP P + F + + + P + D+ + D T+ T+ + S + + C Sbjct: 323 FGRPPPQVTFRKLTAEKAYVKGPQLDDDRIILENSGDDSETIGTLTISQSLRSNDGLYEC 382 Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432 A N G + G LTV + PP + ++ + C A P I W Sbjct: 383 IAQNAGGDARRIGHLTV----EFPPSFASMSNTSVWSWDQKPVNISCIAESIPNATIRWT 438 Query: 433 FEGEALIQNHRRNVTNDGT-----LVLKDLDKSDSGTYTCVASSRHG 474 G+ I N + +T G L + LDK TY C+AS+ HG Sbjct: 439 MYGDQKIDNDKM-ITQIGNGPRSILTIVPLDKRYYTTYKCIASNAHG 484 Score = 104 bits (249), Expect = 2e-20 Identities = 101/367 (27%), Positives = 158/367 (43%), Gaps = 33/367 (8%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 + C+ PSP++ W G L+ ++ H I + L+ + + SD GVY C A+ Sbjct: 135 IQCKVRARPSPSVDWLYNGELIKTNDHYII----DTYALKIKNVQ-ESDDGVYTCRAS-V 188 Query: 91 YGTARSRNATLHVAV-LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149 + T + + V V +R P +G ++C RG P P W K+ Sbjct: 189 FSTGELKERPIRVEVHIRPTVSEMPNPINMIEGKDASIKC-EARGKPPPKFTWVKSLTHQ 247 Query: 150 LFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208 R + D G L I + + DAG YQC A N AGT + I + + +KP +I Sbjct: 248 NLSNVDRFSVDPDTGVLTITNVNRDDAGEYQCTATNLAGTANTNI-MVNVIVKPKIIEFL 306 Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG------GGNMPLGRVKVL---DD----G 255 V + T C+ G P P V +R+ G + R+ + DD G Sbjct: 307 NSTVVE-DKEATLVCKAFGRPPPQVTFRKLTAEKAYVKGPQLDDDRIILENSGDDSETIG 365 Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-NLSPNSVNVESGNVARFTC 314 +L + + +++G Y C A+N+ G G+LTV PPS ++S SV +C Sbjct: 366 TLTISQSLRSNDGLYECIAQNAGGDARRIGHLTVEFPPSFASMSNTSVWSWDQKPVNISC 425 Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV-TVLTINDTDKNDSRNTIVCS 373 A P T+ W++ G++ I DK T + +G ++LTI DK T C Sbjct: 426 IAESIPNATIRWTMYGDQKI-----DNDKM-ITQIGNGPRSILTIVPLDKR-YYTTYKCI 478 Query: 374 AVNYAGS 380 A N G+ Sbjct: 479 ASNAHGT 485 Score = 79.8 bits (188), Expect = 4e-13 Identities = 84/350 (24%), Positives = 144/350 (41%), Gaps = 33/350 (9%) Query: 155 SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQ 214 + +H + +L ++ AG+Y C A A + T+ + P + Sbjct: 69 TELHQDNSLSLFFNSLQEQQAGKYTCKATYANSIQLQKSVTIDTIVAITWDNAPLNQYPI 128 Query: 215 TGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEA 274 G QC+V P P V W + G + ++D +L++ NV +D+G Y+C A Sbjct: 129 LGEDFAIQCKVRARPSPSVDWLYN--GELIKTNDHYIIDTYALKIKNVQESDDGVYTCRA 186 Query: 275 EN-SVGAVSASGY-LTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332 S G + + V+ P+++ PN +N+ G A C A G+P P W + Sbjct: 187 SVFSTGELKERPIRVEVHIRPTVSEMPNPINMIEGKDASIKCEARGKPPPKFTWV----K 242 Query: 333 TIIFPGMSR-DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTS 391 ++ +S D++ +V VLTI + +++D+ C+A N AG++ + V Sbjct: 243 SLTHQNLSNVDRF---SVDPDTGVLTITNVNRDDA-GEYQCTATNLAGTANTNIMVNVIV 298 Query: 392 DDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW--------YFEGEAL----- 438 P II N T+ A C A P P + + Y +G L Sbjct: 299 K----PKIIEF--LNSTVVEDKEATLVCKAFGRPPPQVTFRKLTAEKAYVKGPQLDDDRI 352 Query: 439 -IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 ++N + GTL + +S+ G Y C+A + G G L V+ P Sbjct: 353 ILENSGDDSETIGTLTISQSLRSNDGLYECIAQNAGGDARRIGHLTVEFP 402 Score = 56.0 bits (129), Expect = 6e-06 Identities = 53/190 (27%), Positives = 83/190 (43%), Gaps = 21/190 (11%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHR-SILPAGGLFFL 69 P + E P + + + A++ C A G P P W K +S+ R S+ P G+ + Sbjct: 207 PTVSEMPNPINMIEGKDASIKCEARGKPPPKFTWVKSLTHQNLSNVDRFSVDPDTGVLTI 266 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 + DAG Y C ATN GTA N + V V+ + +E + + L C Sbjct: 267 TNVN---RDDAGEYQCTATNLAGTA---NTNIMVNVIVKPKIIEFLNSTVVEDKEATLVC 320 Query: 130 LPPRGSPEPNVYWKK-NGQTLLFDG----DSRMHLVDGGN-------LVIQDARQTDAGR 177 G P P V ++K + G D R+ L + G+ L I + +++ G Sbjct: 321 -KAFGRPPPQVTFRKLTAEKAYVKGPQLDDDRIILENSGDDSETIGTLTISQSLRSNDGL 379 Query: 178 YQCIARNAAG 187 Y+CIA+NA G Sbjct: 380 YECIAQNAGG 389 Score = 49.6 bits (113), Expect = 5e-04 Identities = 45/170 (26%), Positives = 68/170 (40%), Gaps = 14/170 (8%) Query: 337 PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP 396 PG S+ + D L N + + C A YA S ++ +T+ D Sbjct: 60 PGHSKPPMYTELHQDNSLSLFFNSLQEQQA-GKYTCKAT-YANSIQLQKSVTI---DTIV 114 Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKD 456 N P NQ + C P P + W + GE LI+ + + + L +K+ Sbjct: 115 AITWDNAPLNQYPILGEDFAIQCKVRARPSPSVDWLYNGE-LIKTNDHYIIDTYALKIKN 173 Query: 457 LDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGP 506 + +SD G YTC AS V+S L + PI +H VS +P P Sbjct: 174 VQESDDGVYTCRAS------VFSTGELKERPIRVEVHI--RPTVSEMPNP 215 Score = 36.7 bits (81), Expect = 3.9 Identities = 43/170 (25%), Positives = 73/170 (42%), Gaps = 18/170 (10%) Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG----GLFFLRATHGRVHSDAGV 82 +P ++C A P+ IRW G + D + I G + + R ++ Sbjct: 419 KPVNISCIAESIPNATIRWTMYGDQKI-DNDKMITQIGNGPRSILTIVPLDKRYYT---T 474 Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP---- 138 Y C A+N++GT R RN L A E ++ +A T+ + +PP PE Sbjct: 475 YKCIASNAHGT-RQRNIELREATKPGEMLQAKMAEITA--TTIRFDLVPPSTHPEQPLRT 531 Query: 139 -NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 NV +K++GQT + ++ VD V++ + ++ ARN G Sbjct: 532 INVQYKEDGQTWI-QARNKTWSVD-SYYVLEGLKPQTMYEFRFAARNDVG 579 >UniRef50_Q8WR45 Cluster: Immunoglobulin domain-containing protein Y54G2A.25; n=4; Caenorhabditis elegans|Rep: Immunoglobulin domain-containing protein Y54G2A.25 - Caenorhabditis elegans Length = 1187 Score = 111 bits (266), Expect = 1e-22 Identities = 112/477 (23%), Positives = 194/477 (40%), Gaps = 53/477 (11%) Query: 30 TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP----AGGLFFLRATHGRVHSDAGVYWC 85 TL C A + + W K G V D+ + +G + F + H S G Y C Sbjct: 50 TLRCEADEN-TDRYSWLKDGEPFVIDSEDVLWEKESQSGSIVFTKP-HA---SHQGYYQC 104 Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW--- 142 A+N +GTA S L + L + + + + +G+++ L C PPRG+P+P + W Sbjct: 105 FASNIFGTALSNKMHLRLGSLEHFPKRDVKLLRVKEGESLTLNCTPPRGTPDPKIVWLYR 164 Query: 143 KKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGR---YQCIARNAAGTRESAIAT-LK 197 + +++ SR VD G+L +D Y+C A + E ++ Sbjct: 165 SLDDSSVIETIRSRHITVDNEGHLHFSSVELSDGKATLVYECAATSPVLRGEYRSGDRIQ 224 Query: 198 IHIKPY---------LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248 + I+P + P +V + G + QC GG PLP + W S G +P R Sbjct: 225 LDIEPSQDKSHPVKKMSVSPSEVTVRAGGQLKLQCIFGGRPLPTIFW--SKIDGELPKSR 282 Query: 249 VKVL-----DDG-SLRLDNVILADEGEYSCEAENSVGAVSA---SGYLTVYDPPSINLSP 299 +K L D G SL ++NV D G Y C + V V+ + +DP P Sbjct: 283 IKDLTSHESDFGRSLIVENVHPDDAGAYECRGRHLVHTVNVRVMAAPFWEFDP------P 336 Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359 +++ + C A G+P P + WS+ G ++ D + D +L + Sbjct: 337 RDISLPEESTGELECLAGGQPTPIITWSMNGK---FLHELAEDS--RRVLLDHGRILRVR 391 Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419 + + + C+A N G F + V + P + + + S V C Sbjct: 392 NLNHDLDTGVYQCNASNPLGYVFANAFVHVRA---HAPFFRMPAARHWKVVLHSTVVLDC 448 Query: 420 TAICTPEPIIAWYFEGEALIQ--NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 PE ++ W + +Q + + + T ++ D++ +D G Y C S+++G Sbjct: 449 DVDAAPEAMVRWVDADDRPLQVVEGKNKLFPNHTFMVYDVNSADEGLYYCNVSNKYG 505 Score = 81.4 bits (192), Expect = 1e-13 Identities = 89/326 (27%), Positives = 128/326 (39%), Gaps = 22/326 (6%) Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77 P +VTV L C GG P P I W K + + + F VH Sbjct: 244 PSEVTVRAGGQLKLQCIFGGRPLPTIFWSKIDGELPKSRIKDLTSHESDFGRSLIVENVH 303 Query: 78 -SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136 DAG Y C + T R +A EF P + T LECL G P Sbjct: 304 PDDAGAYECRGRHLVHTVNVR----VMAAPFWEFD-PPRDISLPEESTGELECL-AGGQP 357 Query: 137 EPNVYWKKNGQTL-LFDGDSRMHLVDGGNLV-IQDA-RQTDAGRYQCIARNAAG-TRESA 192 P + W NG+ L DSR L+D G ++ +++ D G YQC A N G +A Sbjct: 358 TPIITWSMNGKFLHELAEDSRRVLLDHGRILRVRNLNHDLDTGVYQCNASNPLGYVFANA 417 Query: 193 IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL----GR 248 ++ H + + S+V C V P V W + PL G+ Sbjct: 418 FVHVRAHAPFFRMPAARHWKVVLHSTVVLDCDVDAAPEAMVRW---VDADDRPLQVVEGK 474 Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP-SINL-SPNSVNVES 306 K+ + + + +V ADEG Y C N G A+ L V+ P + + +P + +E+ Sbjct: 475 NKLFPNHTFMVYDVNSADEGLYYCNVSNKYGINRATNRLQVFKPTYFVRIPTPKRLILEA 534 Query: 307 GNVARFTCTATGRPE-PTMF-WSVEG 330 G A C A P P + W++ G Sbjct: 535 GETAEVFCEAVADPRLPIRYQWTING 560 Score = 81.0 bits (191), Expect = 2e-13 Identities = 74/286 (25%), Positives = 113/286 (39%), Gaps = 13/286 (4%) Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL---VVSDTHRSILPAGGLFFLRAT 72 + P D+++ L C AGG P+P I W G + D+ R +L G + LR Sbjct: 334 DPPRDISLPEESTGELECLAGGQPTPIITWSMNGKFLHELAEDSRRVLLDHGRI--LRVR 391 Query: 73 HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTVVLECL 130 + D GVY C A+N G + NA +HV FR+ P ++ + TVVL+C Sbjct: 392 NLNHDLDTGVYQCNASNPLGYVFA-NAFVHVRAHAPFFRM-PAARHWKVVLHSTVVLDC- 448 Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190 +PE V W L + + L ++ D D G Y C N G Sbjct: 449 DVDAAPEAMVRWVDADDRPLQVVEGKNKLFPNHTFMVYDVNSADEGLYYCNVSNKYGINR 508 Query: 191 SAIATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248 A L++ Y I P+ ++ + G + C DP + ++ + G + + Sbjct: 509 -ATNRLQVFKPTYFVRIPTPKRLILEAGETAEVFCEAVADPRLPIRYQWTINGKVLTESQ 567 Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294 + LR +V G C A V AS L V D P+ Sbjct: 568 YYEILPDRLRFRSVRGRHSGIIDCAAITDVDVKLASMQLIVKDVPA 613 Score = 42.3 bits (95), Expect = 0.078 Identities = 43/183 (23%), Positives = 73/183 (39%), Gaps = 15/183 (8%) Query: 642 TPIDSKTIKLMWEILNFYYLEGLFIYFR----PLDNITIEYEMKTILHSNDVSGFEITSL 697 T I+ TI W ++ + G F+ + +N +Y +K +S I S Sbjct: 831 TQINFTTINFTWNPVDANTVNGHFVGYEIEYWKAENTIRKYSIKIPANSTYKV---INSF 887 Query: 698 RKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPEL 757 T Y + K+ PS+ V+ + + P G N+ ++ + +T + L+W P L Sbjct: 888 HAVTNYSAHIRTRNKRLRSAPSDY-VSFAMPEGPPGKVHNLRVYSVGSTAILLQWDAP-L 945 Query: 758 QLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817 Q NG I GY ++ K+ +H+ + Y V + AET G Sbjct: 946 Q-PNGRIRGY-----FISFQNEKNETEETYVIHRQKHYLHEKSEPDTGYKVSVWAETRAG 999 Query: 818 LGP 820 GP Sbjct: 1000 EGP 1002 >UniRef50_A7SC07 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 862 Score = 111 bits (266), Expect = 1e-22 Identities = 84/272 (30%), Positives = 121/272 (44%), Gaps = 21/272 (7%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDN 261 P I P + + F C G P P ++W + G M K+L +G L L+N Sbjct: 209 PNAIVSPALITINASDTAVFHCAASGVPKPVLIWSKVDGAPLME-SSYKMLGNGRLVLEN 267 Query: 262 VILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESG-NVARFTCTATGRP 320 L D G Y C+A N +G SA+ L V PPS+++ V+ G NV C TG P Sbjct: 268 TTLEDAGLYECKAINLLGESSATMRLVVTVPPSVSIDIGPTYVQEGDNVMLPKCHVTGFP 327 Query: 321 EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGS 380 P + W+ S + V L+I NDS CSA N+ GS Sbjct: 328 LPEINWT-----------RSAGQLPRRRVMTSGGQLSILAARANDS-GDYFCSARNHIGS 375 Query: 381 SFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP-IIAWYFEGEALI 439 + R +L V + P I + P + + S + PC A +P P +I W+ G+++ Sbjct: 376 TIARTQLVVFA----LPRFIISPPKSLKAEVGSDVILPCKAYGSPPPLVITWHRHGKSIP 431 Query: 440 QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471 Q R+ DG L L D+ +DSG Y C A+S Sbjct: 432 Q--ERSGVIDGVLRLIDVTTADSGVYVCTATS 461 Score = 109 bits (262), Expect = 5e-22 Identities = 82/269 (30%), Positives = 123/269 (45%), Gaps = 16/269 (5%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 AP I P +T+ A +C A G P P + W K + ++ +L G L Sbjct: 208 APNAIVSPALITINASDTAVFHCAASGVPKPVLIWSKVDGAPLMESSYKMLGNGRLVLEN 267 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV-LREEFRLEPESKQSAQGDTVVLEC 129 T DAG+Y C+A N G + +AT+ + V + ++ +GD V+L Sbjct: 268 TTL----EDAGLYECKAINLLGES---SATMRLVVTVPPSVSIDIGPTYVQEGDNVMLPK 320 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189 G P P + W ++ L R + GG L I AR D+G Y C ARN G+ Sbjct: 321 CHVTGFPLPEINWTRSAGQL----PRRRVMTSGGQLSILAARANDSGDYFCSARNHIGST 376 Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL-WRRSAGGGNMPLGR 248 + + + ++I+ P+ + A+ GS V C+ G P P V+ W R G ++P R Sbjct: 377 IARTQLVVFALPRFIISPPKSLKAEVGSDVILPCKAYGSPPPLVITWHRH--GKSIPQER 434 Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENS 277 V+ DG LRL +V AD G Y C A +S Sbjct: 435 SGVI-DGVLRLIDVTTADSGVYVCTATSS 462 Score = 45.6 bits (103), Expect = 0.008 Identities = 33/111 (29%), Positives = 55/111 (49%), Gaps = 3/111 (2%) Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-YFEGEALIQN 441 VRG+ D P I + P+ T+ AVF C A P+P++ W +G L+++ Sbjct: 195 VRGEKGAPGDTLSAPNAIVS-PALITINASDTAVFHCAASGVPKPVLIWSKVDGAPLMES 253 Query: 442 HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492 + + N G LVL++ D+G Y C A + G+ + L+V P + +I Sbjct: 254 SYKMLGN-GRLVLENTTLEDAGLYECKAINLLGESSATMRLVVTVPPSVSI 303 >UniRef50_Q8AXY6 Cluster: Muscle, skeletal receptor tyrosine protein kinase precursor; n=18; Gnathostomata|Rep: Muscle, skeletal receptor tyrosine protein kinase precursor - Gallus gallus (Chicken) Length = 947 Score = 110 bits (265), Expect = 2e-22 Identities = 73/231 (31%), Positives = 116/231 (50%), Gaps = 10/231 (4%) Query: 7 TSGEAPYIIEQPLDVTVARHQPAT-LNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAG 64 T +AP+I PL+ A + C P P I W + + + + DT SI G Sbjct: 23 TLQKAPFI-STPLETVDALVEDVPKFVCVVESYPEPEITWTRNSIPIRLFDTRYSIQRNG 81 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124 L + + SD GVY C A N G A L V +R + P + + +G Sbjct: 82 QLLTILSVED---SDDGVYCCTADNGVGAAAQSCGALQVK-MRPKITRPPVNVEIIEGLK 137 Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 VL C G+P+P+V W K G+T++ + ++R+ ++D GNL I + ++ DAG+Y+C+A+N Sbjct: 138 AVLPCTT-MGNPKPSVSWIK-GETVVKE-NARIAVLDSGNLRIHNVQREDAGQYRCVAKN 194 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235 + G+ S AT+ + + ++ PE GS VT +C G P+P V W Sbjct: 195 SLGSAYSKPATVVVEVFARILKAPESQNITFGSMVTLRCTAAGAPVPTVTW 245 Score = 102 bits (244), Expect = 7e-20 Identities = 64/198 (32%), Positives = 92/198 (46%), Gaps = 6/198 (3%) Query: 136 PEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAI 193 PEP + W +N + LFD +R + G L+ I +D G Y C A N G + Sbjct: 55 PEPEITWTRNSIPIRLFD--TRYSIQRNGQLLTILSVEDSDDGVYCCTADNGVGAAAQSC 112 Query: 194 ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD 253 L++ ++P + P +V G C G+P P V W + R+ VLD Sbjct: 113 GALQVKMRPKITRPPVNVEIIEGLKAVLPCTTMGNPKPSVSWIKGETVVKEN-ARIAVLD 171 Query: 254 DGSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSPNSVNVESGNVARF 312 G+LR+ NV D G+Y C A+NS+G A S + V I +P S N+ G++ Sbjct: 172 SGNLRIHNVQREDAGQYRCVAKNSLGSAYSKPATVVVEVFARILKAPESQNITFGSMVTL 231 Query: 313 TCTATGRPEPTMFWSVEG 330 CTA G P PT+ W G Sbjct: 232 RCTAAGAPVPTVTWLENG 249 Score = 89.4 bits (212), Expect = 5e-16 Identities = 75/277 (27%), Positives = 120/277 (43%), Gaps = 17/277 (6%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLD 260 P++ T E V A F C V P P++ W R++ + R + +G L + Sbjct: 28 PFISTPLETVDALVEDVPKFVCVVESYPEPEITWTRNSIPIRLFDTRYSIQRNGQLLTIL 87 Query: 261 NVILADEGEYSCEAENSVGAVSAS-GYLTVYDPPSINLSPNSVNVESGNVARFTCTATGR 319 +V +D+G Y C A+N VGA + S G L V P I P +V + G A CT G Sbjct: 88 SVEDSDDGVYCCTADNGVGAAAQSCGALQVKMRPKITRPPVNVEIIEGLKAVLPCTTMGN 147 Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379 P+P++ W ++G + + AV D L I++ + D+ C A N G Sbjct: 148 PKPSVSW-IKGETVV-------KENARIAVLDSGN-LRIHNVQREDA-GQYRCVAKNSLG 197 Query: 380 SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI 439 S++ + V R I P +Q + SM CTA P P + W G+A+ Sbjct: 198 SAYSKPATVVVEVFAR----ILKAPESQNITFGSMVTLRCTAAGAPVPTVTWLENGKAVS 253 Query: 440 QNHRRNVTNDGTLVLK-DLDKSDSGTYTCVASSRHGK 475 D + + + + G +TC+A+++H K Sbjct: 254 AGSIAESVKDRVVDSRLQVYVTRPGLFTCLATNKHSK 290 Score = 79.8 bits (188), Expect = 4e-13 Identities = 47/138 (34%), Positives = 67/138 (48%), Gaps = 6/138 (4%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I P++V + A L C G+P P++ W KG +V + ++L +G L Sbjct: 121 PKITRPPVNVEIIEGLKAVLPCTTMGNPKPSVSWIKGETVVKENARIAVLDSGNL----R 176 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131 H DAG Y C A NS G+A S+ AT+ V V + PES+ G V L C Sbjct: 177 IHNVQREDAGQYRCVAKNSLGSAYSKPATVVVEVFARILKA-PESQNITFGSMVTLRCTA 235 Query: 132 PRGSPEPNVYWKKNGQTL 149 G+P P V W +NG+ + Sbjct: 236 A-GAPVPTVTWLENGKAV 252 Score = 66.1 bits (154), Expect = 6e-09 Identities = 62/257 (24%), Positives = 110/257 (42%), Gaps = 20/257 (7%) Query: 288 TVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347 T+ P I+ +V+ +V +F C PEP + W+ R I + +Y Sbjct: 23 TLQKAPFISTPLETVDALVEDVPKFVCVVESYPEPEITWT----RNSIPIRLFDTRYSIQ 78 Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR-GKLTVTSDDDRPPPIITNGPSN 406 +T+L++ D+D C+A N G++ G L V + P IT P N Sbjct: 79 RNGQLLTILSVEDSDDG----VYCCTADNGVGAAAQSCGALQV-----KMRPKITRPPVN 129 Query: 407 QTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI-QNHRRNVTNDGTLVLKDLDKSDSGTY 465 + AV PCT + P+P ++W +GE ++ +N R V + G L + ++ + D+G Y Sbjct: 130 VEIIEGLKAVLPCTTMGNPKPSVSW-IKGETVVKENARIAVLDSGNLRIHNVQREDAGQY 188 Query: 466 TCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSV-TLSW 524 CVA + G A +V + +A + ++ + V T++W Sbjct: 189 RCVAKNSLGSAYSKPATVV---VEVFARILKAPESQNITFGSMVTLRCTAAGAPVPTVTW 245 Query: 525 SQNNKIGSSSILGYQVE 541 +N K S+ + V+ Sbjct: 246 LENGKAVSAGSIAESVK 262 >UniRef50_Q9I7U4-3 Cluster: Isoform B of Q9I7U4 ; n=6; Sophophora|Rep: Isoform B of Q9I7U4 - Drosophila melanogaster (Fruit fly) Length = 17903 Score = 110 bits (264), Expect = 3e-22 Identities = 117/420 (27%), Positives = 184/420 (43%), Gaps = 48/420 (11%) Query: 119 SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGR 177 S +GD V EC G+PEP V W K+G ++ + D + G LVI++ D+ R Sbjct: 236 SREGDRFVFEC-EVTGTPEPAVEWFKDGISIQTNSDYKTTFDKGICRLVIEETFAADSAR 294 Query: 178 YQCIARNAAGTRESAIATLKIH--------IKPYLITGPEDVVAQTGSSVTFQCRVGGDP 229 + C A N GT ++ ATL + + P ++ + A GSS F C V G P Sbjct: 295 FSCRASNLVGTCDTN-ATLSVRENAAEVQLVPPRILRFLQSGKATEGSSFQFACVVAGVP 353 Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYL 287 LP V W ++ + V ++G +L+ + V L D+ Y+C A N G S L Sbjct: 354 LPTVQWFKNDKCIDDSPDYVISYNNGEATLKFEEVFLEDDAVYTCSASNPAGIEHCSASL 413 Query: 288 TV--YDP---PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRD 342 V +P PS + ++ G + G P P ++W G P RD Sbjct: 414 IVEPLEPTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWLHNGK-----PFQPRD 468 Query: 343 KYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF------VRGKL-TVTSDDDR 395 + G L I ND+ + V SA N AG ++ V+G+L TSD + Sbjct: 469 SKYEY----GRVTLIIPQAYPNDA-GSYVLSAKNLAGEAYTSCNVIVKGRLPNETSDSEM 523 Query: 396 PPPIITNGPSNQTLPIKSMAVFP-------CTAICTPEPIIAWYFEGEALIQNHRRNVTN 448 I P+ LP+K +++F C + PEP + WY + ++ + Sbjct: 524 ASDIEPIKPAVH-LPLKDVSIFEGKPVRLDCVIVGQPEPEVIWYHNERPVKESADVQLLF 582 Query: 449 DG---TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRA-ADVSSLP 504 G +L+++++ + D+G Y VA + G+ S L V +P+N RA A+ SLP Sbjct: 583 QGDRCSLIIQEVYQEDAGHYKVVAINSAGEASSSCELKV-TPLNQAEPATRAQAERQSLP 641 Score = 96.7 bits (230), Expect = 3e-18 Identities = 96/383 (25%), Positives = 160/383 (41%), Gaps = 45/383 (11%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV--- 166 F +P+++ + V+LEC PEP++ W NG+ + + + +V ++ Sbjct: 16059 FSKKPKAQYVDENTNVILECRLV-AVPEPDIVWTFNGEDIDEEEIKNVRIVTESDMHMYC 16117 Query: 167 ----IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK----PYLITGPEDVVAQTGSS 218 I +++ G Y+ IA N G I TLK+ P ++ ++V + G S Sbjct: 16118 SVVHISKVKKSQEGTYEVIATNREGEARLPI-TLKVRTTDKEAPQILEPLRNMVIREGES 16176 Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGEYSCEAENS 277 V ++ G+P P V W + P+ K D +L L +++GEY+ +A N Sbjct: 16177 VVLSTQIVGNPPPKVTWYKDG----KPVKNAKSDKDLHTLTLITPQKSEKGEYTVKAVNP 16232 Query: 278 VGAVSASGYLTVYDPPSINLSP-------NSVNVESGNVARFTCTATGRPEPTMFWSVEG 330 +G+V + LT+ +P N P NV R +G P P + W Sbjct: 16233 LGSVETTANLTIEEPAGGNAEPPLFVERFEEQNVPQKGEIRLPAKVSGNPVPEVQWLF-- 16290 Query: 331 NRTIIFPGMSRDKYHATAVFDGVTV-LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389 N T +FP + V+DG + L I D + C A N G + ++ V Sbjct: 16291 NNTPLFPSERIQQ-----VYDGENIELIIKDANPETDSGDYKCIASNPIGKTSHGARVIV 16345 Query: 390 TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA--WYFEGEALIQNHRRNVT 447 D+ + +T+ I+ V T C ++ W+F G+ L R V Sbjct: 16346 EVDE-----VTFTKKLKKTITIEE--VQSLTLECETSHVVTTKWFFNGKELSGMDHRVVV 16398 Query: 448 NDGT---LVLKDLDKSDSGTYTC 467 DG LV+++ + DSGTYTC Sbjct: 16399 EDGKTHKLVIRNTNLRDSGTYTC 16421 Score = 94.7 bits (225), Expect = 1e-17 Identities = 102/356 (28%), Positives = 148/356 (41%), Gaps = 34/356 (9%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 V +AP ++ V ++ A G P+P ++WY+ + + I G Sbjct: 6024 VKPAKAPVFTKKIQPCRVFENEQAKFEVEFEGEPNPTVKWYRESFPIQNSPDLQIHTFSG 6083 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR--LEPES-KQSAQG 122 L V D+ V+ C A N GTA+ +A L V R + ++P S + Q Sbjct: 6084 KSILIIRQVFVE-DSAVFSCVAENRGGTAKC-SANLVVEERRRAGKGGIQPPSFVTTIQS 6141 Query: 123 DTVVLECLPP-----RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAG 176 TV L G+ +VYW KNG + +M D + L+I + D+G Sbjct: 6142 TTVATGQLARFDAKVTGTRPLDVYWLKNGMKIQPSIKFKMLEEDSVHTLLIIEPFAEDSG 6201 Query: 177 RYQCIARNAAG-TRESAIATLKIHIKPYLITGP---------EDVVAQT---GSSVTFQC 223 RY+C+A NAAG R ++ KP T P E + +QT GS V F+C Sbjct: 6202 RYECVAVNAAGEARCDGDCIVQSPSKPEKPTTPGSEKAPHIVEQLKSQTVEEGSKVIFRC 6261 Query: 224 RVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGA 280 RV G P P W R P ++ G L + DEG Y C AEN +G+ Sbjct: 6262 RVDGKPTPTARWMRGENFVK-PSRYFQMSRQGEYYQLVISEAFPEDEGTYKCVAENKLGS 6320 Query: 281 VSASGYLTV-----YDPPSINLSPNSVNVESGNVARFTCTATGRPEPT-MFWSVEG 330 + S L V D P + V+V G A+F T TG+ + T + W EG Sbjct: 6321 IQTSAQLKVRPIENLDAPPTITALKDVSVTEGMPAQFKTTVTGKVKATSVQWFREG 6376 Score = 87.4 bits (207), Expect = 2e-15 Identities = 105/435 (24%), Positives = 172/435 (39%), Gaps = 43/435 (9%) Query: 14 IIEQPLDVTVARHQPA-TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRAT 72 + +PL V+R C G+P PA+ W+K G+ + +++ G+ L Sbjct: 226 LFTRPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTFDKGICRL-VI 284 Query: 73 HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-------ESKQSAQGDTV 125 +D+ + C A+N GT + NATL V E +L P +S ++ +G + Sbjct: 285 EETFAADSARFSCRASNLVGTCDT-NATLSVRENAAEVQLVPPRILRFLQSGKATEGSSF 343 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARN 184 C+ G P P V W KN + + D + +G L ++ D Y C A N Sbjct: 344 QFACVVA-GVPLPTVQWFKNDKCIDDSPDYVISYNNGEATLKFEEVFLEDDAVYTCSASN 402 Query: 185 AAGTRESAIATLKIHIKPYLITG---P-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 AG + + + ++P + P + +A+ G + + VGG P P+V W + Sbjct: 403 PAGIEHCSASLIVEPLEPTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWLHNGK 462 Query: 241 -----GGNMPLGRVKVL-------DDGSLRLDNVILADEGEYSCEA---ENSVGAVSASG 285 GRV ++ D GS L LA E SC S S Sbjct: 463 PFQPRDSKYEYGRVTLIIPQAYPNDAGSYVLSAKNLAGEAYTSCNVIVKGRLPNETSDSE 522 Query: 286 YLTVYDP--PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDK 343 + +P P+++L V++ G R C G+PEP + W R + ++ Sbjct: 523 MASDIEPIKPAVHLPLKDVSIFEGKPVRLDCVIVGQPEPEVIW-YHNERPV------KES 575 Query: 344 YHATAVFDGVTV-LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN 402 +F G L I + + D+ + V A+N AG + +L VT + P Sbjct: 576 ADVQLLFQGDRCSLIIQEVYQEDAGHYKVV-AINSAGEASSSCELKVTPLNQAEPATRAQ 634 Query: 403 GPSNQTLPIKSMAVF 417 Q+LP S F Sbjct: 635 A-ERQSLPKDSQPKF 648 Score = 84.6 bits (200), Expect = 1e-14 Identities = 108/496 (21%), Positives = 185/496 (37%), Gaps = 42/496 (8%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I E+ +P L C+ G P P I+WY +L+ + I + L+ Sbjct: 8090 PRITEKLRPRQCVPEEPTVLECKVEGVPFPEIKWYFNDILLFASEKYEITVMEQVAKLKI 8149 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131 SD GVY CEA N G A SR + + + ++E ++ + V + C Sbjct: 8150 AK-VTPSDVGVYTCEAKNEAGVATSR-TNIILGKFTKPLKIEFIEEKQPERLKVTVTC-Q 8206 Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQT--DAGRYQCIARNAAGT 188 G P P V W + + ++ +M + G++ ++ T +A Y A+N G Sbjct: 8207 VTGKPNPEVKWYRGIEEVIPSETVQMFYDEKTGDVALEVINPTPNEAVVYSVQAQNQFGR 8266 Query: 189 RESAIATL-------KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241 L + +K +T VV TG ++ F+ + G P P+V W R+ G Sbjct: 8267 AIGNANILSRVDEVPREILKAPTVTPLSAVVVPTGGTLFFEAKYDGLPRPEVKWMRN--G 8324 Query: 242 GNMPLGRVKVLD----DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD------ 291 + +++ ++++ N+ G+Y A+N VG +SG + V D Sbjct: 8325 REIIENEETIIETTETTTTIKVVNMTRKRTGKYEVWAKNKVGEAKSSGSVVVSDQKPDEQ 8384 Query: 292 --PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349 PP VA P + W V P S ++ + Sbjct: 8385 IKPPRFIQPLEPKYFGEHEVAIIEAIVESEPLSSFQWFVHNE-----PIKSSNEVRIVSQ 8439 Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409 + T+L N K C A N GS + + ++ Sbjct: 8440 ANKSTLLIENFQSK--FVGPFTCRAENVGGSVTSTATVNLIPQEEAEEFESPRFVEELVQ 8497 Query: 410 PIKSM----AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND--GT--LVLKDLDKSD 461 P++ M + C P P + WY E + +N ++ D G L + ++ + Sbjct: 8498 PVEVMDGEALLLTCQVTGKPTPKVEWYHNAEKITENKETTISQDLQGVCQLQITEVFPEN 8557 Query: 462 SGTYTCVASSRHGKYV 477 G Y CVA+++ GK V Sbjct: 8558 EGQYECVATNKIGKSV 8573 Score = 84.2 bits (199), Expect = 2e-14 Identities = 77/312 (24%), Positives = 126/312 (40%), Gaps = 30/312 (9%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 +AP I ++P + A R G +P P + W+ G +V+ I + G+ L Sbjct: 1978 QAPQISQKPRSSKLIEGSDAVFTARVGSNPKPRLTWFHNGQRLVASQKYEISYSSGVATL 2037 Query: 70 RATHGRVHSDAGVYWCEATNSYG------------TARSRNATLHVAVLREEF---RLEP 114 R + D G Y A N G A + V V+ E+ + P Sbjct: 2038 RVKNATAR-DGGHYTLLAENLQGCVVSSAVLAVEPAAETAYEPKPVDVMAEQLEAGKALP 2096 Query: 115 ESKQSAQGDTVVLECLPPR------GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LV 166 + A GD + E R G+P P V+W NG+ + D ++ + + G+ L+ Sbjct: 2097 PAFVKAFGDREITEGRMTRFDCRVTGNPYPEVFWLINGRQVRDDASHKILVNESGSHSLM 2156 Query: 167 IQDARQTDAGRYQCIARNAAG--TRESAIATLKIH--IKPYLITGPEDVVAQTGSSVTFQ 222 I + + DAG QC+ARN AG E+ + L+ + P + + + G +T Sbjct: 2157 ITNVTRLDAGAVQCLARNKAGEVAIEAQLNVLEKEQVVAPQFVQRFSTMTVREGEPITMS 2216 Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS--LRLDNVILADEGEYSCEAENSVGA 280 G P P + W++ + R +D G+ L + V D G Y C A+N G+ Sbjct: 2217 ANAIGTPQPRITWQKDGVQISSTAERFVGIDGGATCLEIPRVTANDAGWYQCTAQNIAGS 2276 Query: 281 VSASGYLTVYDP 292 + L V P Sbjct: 2277 TANRARLYVEVP 2288 Score = 79.0 bits (186), Expect = 7e-13 Identities = 94/352 (26%), Positives = 132/352 (37%), Gaps = 47/352 (13%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS----L 257 P + P GS F RVG +P P + W + G + + + S L Sbjct: 1980 PQISQKPRSSKLIEGSDAVFTARVGSNPKPRLTWFHN--GQRLVASQKYEISYSSGVATL 2037 Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYL-------TVYDPPSIN-----------LSP 299 R+ N D G Y+ AEN G V +S L T Y+P ++ L P Sbjct: 2038 RVKNATARDGGHYTLLAENLQGCVVSSAVLAVEPAAETAYEPKPVDVMAEQLEAGKALPP 2097 Query: 300 NSVN------VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD-G 352 V + G + RF C TG P P +FW + G + + D H V + G Sbjct: 2098 AFVKAFGDREITEGRMTRFDCRVTGNPYPEVFWLINGRQ------VRDDASHKILVNESG 2151 Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412 L I + + D+ + C A N AG + +L V + P S T+ Sbjct: 2152 SHSLMITNVTRLDA-GAVQCLARNKAGEVAIEAQLNVLEKEQVVAPQFVQRFSTMTVREG 2210 Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVA 469 AI TP+P I W +G + R V DG L + + +D+G Y C A Sbjct: 2211 EPITMSANAIGTPQPRITWQKDGVQISSTAERFVGIDGGATCLEIPRVTANDAGWYQCTA 2270 Query: 470 SSRHGKYVWSGALLVDSP-INPNIHFFRAADVSSLPGPPTKPITHNVTDTSV 520 + G L V+ P PN R +LP PTK I TSV Sbjct: 2271 QNIAGSTANRARLYVEVPREQPNYEQRRL----NLP-RPTKVIEPGARATSV 2317 Score = 72.1 bits (169), Expect = 8e-11 Identities = 92/335 (27%), Positives = 130/335 (38%), Gaps = 48/335 (14%) Query: 221 FQCRVGGDPLPDVLW-RRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSV 278 F+ G+P P V W R S N P ++ S L + V + D +SC AEN Sbjct: 6049 FEVEFEGEPNPTVKWYRESFPIQNSPDLQIHTFSGKSILIIRQVFVEDSAVFSCVAENRG 6108 Query: 279 GAVSASGYLTVYD----------PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328 G S L V + PPS + S V +G +ARF TG ++W Sbjct: 6109 GTAKCSANLVVEERRRAGKGGIQPPSFVTTIQSTTVATGQLARFDAKVTGTRPLDVYWLK 6168 Query: 329 EGNR---TIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385 G + +I F + D H T+L I ++ R C AVN AG + G Sbjct: 6169 NGMKIQPSIKFKMLEEDSVH--------TLLIIEPFAEDSGRYE--CVAVNAAGEARCDG 6218 Query: 386 KLTVTSDD--DRPP-------PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436 V S ++P P I +QT+ S +F C P P W GE Sbjct: 6219 DCIVQSPSKPEKPTTPGSEKAPHIVEQLKSQTVEEGSKVIFRCRVDGKPTPTARW-MRGE 6277 Query: 437 ALIQNHRR-NVTNDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV------DS 486 ++ R ++ G LV+ + D GTY CVA ++ G S L V D+ Sbjct: 6278 NFVKPSRYFQMSRQGEYYQLVISEAFPEDEGTYKCVAENKLGSIQTSAQLKVRPIENLDA 6337 Query: 487 PINPNIHFFRAADVS-SLPGPPTKPITHNVTDTSV 520 P P I + V+ +P +T V TSV Sbjct: 6338 P--PTITALKDVSVTEGMPAQFKTTVTGKVKATSV 6370 Score = 70.1 bits (164), Expect = 3e-10 Identities = 74/338 (21%), Positives = 131/338 (38%), Gaps = 30/338 (8%) Query: 166 VIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV 225 +I ++ +D G + +RES++A + I P P+ ++V +CR+ Sbjct: 16021 LIVESPLSDHGSDATALSRRSMSRESSLADILEGIPPTFSKKPKAQYVDENTNVILECRL 16080 Query: 226 GGDPLPDVLWRRSAGG-GNMPLGRVKVLDDGSL-------RLDNVILADEGEYSCEAENS 277 P PD++W + + V+++ + + + V + EG Y A N Sbjct: 16081 VAVPEPDIVWTFNGEDIDEEEIKNVRIVTESDMHMYCSVVHISKVKKSQEGTYEVIATNR 16140 Query: 278 VG----AVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRT 333 G ++ T + P I ++ + G + G P P + W +G Sbjct: 16141 EGEARLPITLKVRTTDKEAPQILEPLRNMVIREGESVVLSTQIVGNPPPKVTWYKDGKPV 16200 Query: 334 IIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV--TS 391 DK T +T++T ++K + AVN GS LT+ + Sbjct: 16201 ---KNAKSDKDLHT-----LTLITPQKSEKGE----YTVKAVNPLGSVETTANLTIEEPA 16248 Query: 392 DDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG- 450 + PP+ Q +P K P P P + W F L + R DG Sbjct: 16249 GGNAEPPLFVERFEEQNVPQKGEIRLPAKVSGNPVPEVQWLFNNTPLFPSERIQQVYDGE 16308 Query: 451 --TLVLKDLD-KSDSGTYTCVASSRHGKYVWSGALLVD 485 L++KD + ++DSG Y C+AS+ GK ++V+ Sbjct: 16309 NIELIIKDANPETDSGDYKCIASNPIGKTSHGARVIVE 16346 Score = 66.9 bits (156), Expect = 3e-09 Identities = 77/322 (23%), Positives = 114/322 (35%), Gaps = 24/322 (7%) Query: 204 LITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL--D 260 L T P +D V++ G F+C V G P P V W + D G RL + Sbjct: 226 LFTRPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTFDKGICRLVIE 285 Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVYD--------PPSINLSPNSVNVESGNVARF 312 AD +SC A N VG + L+V + PP I S G+ +F Sbjct: 286 ETFAADSARFSCRASNLVGTCDTNATLSVRENAAEVQLVPPRILRFLQSGKATEGSSFQF 345 Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372 C G P PT+ W + ++ I S D + + +G L + D C Sbjct: 346 ACVVAGVPLPTVQW-FKNDKCI---DDSPD--YVISYNNGEATLKFEEVFLEDDA-VYTC 398 Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432 SA N AG L V + P SN + P P + W Sbjct: 399 SASNPAGIEHCSASLIVEPLEPTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWL 458 Query: 433 FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPI-NPN 491 G+ + TL++ +D+G+Y A + G+ S ++V + N Sbjct: 459 HNGKPFQPRDSKYEYGRVTLIIPQAYPNDAGSYVLSAKNLAGEAYTSCNVIVKGRLPNET 518 Query: 492 IHFFRAADVSSLPGPPTKPITH 513 A+D+ P KP H Sbjct: 519 SDSEMASDIE-----PIKPAVH 535 Score = 66.1 bits (154), Expect = 6e-09 Identities = 122/490 (24%), Positives = 183/490 (37%), Gaps = 57/490 (11%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD---THRSILP 62 + G P ++P V + L CR P P I W G + + R + Sbjct: 16051 ILEGIPPTFSKKPKAQYVDENTNVILECRLVAVPEPDIVWTFNGEDIDEEEIKNVRIVTE 16110 Query: 63 AGGLFFLRATH-GRVH-SDAGVYWCEATNSYGTARSRNATLHVAVLREEFR--LEP-ESK 117 + + H +V S G Y ATN G AR TL V +E LEP + Sbjct: 16111 SDMHMYCSVVHISKVKKSQEGTYEVIATNREGEARLP-ITLKVRTTDKEAPQILEPLRNM 16169 Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL-FDGDSRMHLVDGGNLVIQDARQTDAG 176 +G++VVL G+P P V W K+G+ + D +H L + ++++ G Sbjct: 16170 VIREGESVVLSTQIV-GNPPPKVTWYKDGKPVKNAKSDKDLH-----TLTLITPQKSEKG 16223 Query: 177 RYQCIARNAAGTRESAIATLKI------HIKPYLITG--PEDVVAQTGSSVTFQCRVGGD 228 Y A N G+ E+ A L I + +P L E V Q G + +V G+ Sbjct: 16224 EYTVKAVNPLGSVETT-ANLTIEEPAGGNAEPPLFVERFEEQNVPQKGE-IRLPAKVSGN 16281 Query: 229 PLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL-----ADEGEYSCEAENSVGAVSA 283 P+P+V W + P R++ + DG ++ +I D G+Y C A N +G S Sbjct: 16282 PVPEVQWLFN-NTPLFPSERIQQVYDGE-NIELIIKDANPETDSGDYKCIASNPIGKTS- 16338 Query: 284 SGYLTVYDPPSINLSPN-SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRD 342 G + + + + + V T T W G GM Sbjct: 16339 HGARVIVEVDEVTFTKKLKKTITIEEVQSLTLECETSHVVTTKWFFNGKE---LSGMD-- 16393 Query: 343 KYHATAVFDGVT-VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401 H V DG T L I +T+ DS T C S V R P I Sbjct: 16394 --HRVVVEDGKTHKLVIRNTNLRDS-GTYTCKVKKQETQSTVEVL-------QRKPDFI- 16442 Query: 402 NGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI-QNHRRNVTNDGT---LVLKDL 457 + + K A+ + T + WY +GE + +N DG LV++D+ Sbjct: 16443 KVLEDYEVTEKDTAILD-VELTTEATEVTWYKDGEKITPENKNVEFIKDGKARRLVIRDV 16501 Query: 458 DKSDSGTYTC 467 D G YTC Sbjct: 16502 TIHDEGQYTC 16511 Score = 62.1 bits (144), Expect = 9e-08 Identities = 48/159 (30%), Positives = 74/159 (46%), Gaps = 6/159 (3%) Query: 37 GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96 G PSP I+ K G + D H I + V DAG Y A+N+ G + S Sbjct: 1002 GFPSPEIKVEKNGGQLFEDAHTRISNKCNRVTIELKQVGV-GDAGRYAVTASNTVGQSTS 1060 Query: 97 R-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155 + + + F +++ S +G+ + +E + G PEP V W K+ + L G S Sbjct: 1061 TADLVVKKTIFPPVFGRRLQAQVSKKGEKLTME-VEVTGLPEPTVTWLKDDKPLKDAGIS 1119 Query: 156 RMHLVDGGN---LVIQDARQTDAGRYQCIARNAAGTRES 191 L+ GN L+I+ A+ TD+G+Y A NA G +S Sbjct: 1120 EHRLLAQGNSYRLIIEKAQTTDSGKYMVRATNAGGEAKS 1158 Score = 60.9 bits (141), Expect = 2e-07 Identities = 106/473 (22%), Positives = 178/473 (37%), Gaps = 38/473 (8%) Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPAGGL 66 + E P +E+ + V + L + G+P P ++W + L S+ + + G Sbjct: 16251 NAEPPLFVERFEEQNVPQKGEIRLPAKVSGNPVPEVQWLFNNTPLFPSERIQQVYD-GEN 16309 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126 L +D+G Y C A+N G S A + V V +E + K++ + V Sbjct: 16310 IELIIKDANPETDSGDYKCIASNPIGKT-SHGARVIVEV--DEVTFTKKLKKTITIEEVQ 16366 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIARN 184 L S W NG+ L D R+ + DG LVI++ D+G Y C + Sbjct: 16367 SLTLECETSHVVTTKWFFNGKE-LSGMDHRVVVEDGKTHKLVIRNTNLRDSGTYTCKVKK 16425 Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 +E+ + KP I ED + + + +V W + Sbjct: 16426 ----QETQSTVEVLQRKPDFIKVLEDYEVTEKDTAILDVELTTE-ATEVTWYKDGEKITP 16480 Query: 245 PLGRVKVLDDGSLR---LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301 V+ + DG R + +V + DEG+Y+C+ E G + + + PP I N Sbjct: 16481 ENKNVEFIKDGKARRLVIRDVTIHDEGQYTCKIE---GQECSCELVVIELPPEIVEPLND 16537 Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361 V V G A F + + + W G + I+F ++ A+ L I Sbjct: 16538 VAVTKGENAVFE-VELSKGDALVKWFKNG-KEIVF-----NERIQLAIDGKKQSLRIVKA 16590 Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421 D V G + KLTV + P + TL K+ Sbjct: 16591 KPEDVGEYSV-----QVGEQTSKAKLTV----EEPLVDFVIRLPDITLATKTTDAEFTVQ 16641 Query: 422 ICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASS 471 + P+ + W +G+ + N + V +GT LV+ D D+G +CVA + Sbjct: 16642 LSQPDVEVTWCKKGKPIKPNQKHEVFVEGTVRRLVIHDASDEDAGEISCVAEN 16694 Score = 56.4 bits (130), Expect = 4e-06 Identities = 35/99 (35%), Positives = 50/99 (50%), Gaps = 2/99 (2%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 AP +++ +TV +P T++ A G+P P I W K GV + S R + GG L Sbjct: 2195 APQFVQRFSTMTVREGEPITMSANAIGTPQPRITWQKDGVQISSTAERFVGIDGGATCLE 2254 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE 109 +DAG Y C A N G+ +R A L+V V RE+ Sbjct: 2255 IPRVTA-NDAGWYQCTAQNIAGSTANR-ARLYVEVPREQ 2291 Score = 54.0 bits (124), Expect = 2e-05 Identities = 55/228 (24%), Positives = 91/228 (39%), Gaps = 16/228 (7%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I+E DV V + + A + ++W+K G +V + + G LR Sbjct: 16529 PEIVEPLNDVAVTKGENAVFEVELSKGDA-LVKWFKNGKEIVFNERIQLAIDGKKQSLRI 16587 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131 + D G Y + A+ T+ ++ RL P+ + + T E Sbjct: 16588 VKAKPE-DVGEYSVQVGEQTSKAK---LTVEEPLVDFVIRL-PDITLATK--TTDAEFTV 16640 Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGTR 189 P+ V W K G+ + + + V+G LVI DA DAG C+A N + Sbjct: 16641 QLSQPDVEVTWCKKGKPIKPNQKHEV-FVEGTVRRLVIHDASDEDAGEISCVAENVTSST 16699 Query: 190 ESAIATLKIHIKPYLITGPED--VVAQTGSSVTFQCRVGGDPLPDVLW 235 + + LK+ P +IT +D + + VTF + G P P+ W Sbjct: 16700 KLCVEELKL---PPVITSDKDQTIKVKENDDVTFTVKYTGVPTPEACW 16744 Score = 54.0 bits (124), Expect = 2e-05 Identities = 43/196 (21%), Positives = 81/196 (41%), Gaps = 14/196 (7%) Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD--GSLRLDNV 262 +T +DVV++ VT C GG P P V W+++ G + R ++ ++ Sbjct: 16768 LTIKKDVVSELDKEVTLSCVFGGIPEPKVTWKKN---GQVFESRSIRYENRVAKYTIEKT 16824 Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN--SVNVESGNVARFTCTATGRP 320 + E Y+C A N G+ S L + P + + + + +G++ T G P Sbjct: 16825 TIETEATYTCVATNEKGSAETSCRLKLQQKPVLEVEDKYLTQKLRTGSILTIPATVRGYP 16884 Query: 321 EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGS 380 +PT+ W E ++ + T+ + T+ + S V +A N +G+ Sbjct: 16885 QPTVTWHKETIEQKTTKSVTIETTETTSTY------TVKKVTREQSGKYKV-TATNESGT 16937 Query: 381 SFVRGKLTVTSDDDRP 396 ++V + V RP Sbjct: 16938 TYVECTVQVIDKPSRP 16953 Score = 50.0 bits (114), Expect = 4e-04 Identities = 77/311 (24%), Positives = 130/311 (41%), Gaps = 35/311 (11%) Query: 43 IRWYKGGVLVVSDTHR-SILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATL 101 + WYK G + + + G L +H D G Y C+ + + L Sbjct: 16469 VTWYKDGEKITPENKNVEFIKDGKARRLVIRDVTIH-DEGQYTCKIEG-----QECSCEL 16522 Query: 102 HVAVLREEFRLEPESKQSA-QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL- 159 V L E +EP + + +G+ V E +G + V W KNG+ ++F+ R+ L Sbjct: 16523 VVIELPPEI-VEPLNDVAVTKGENAVFEVELSKG--DALVKWFKNGKEIVFN--ERIQLA 16577 Query: 160 VDGG--NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGS 217 +DG +L I A+ D G Y A T++ + ++I P+ +A + Sbjct: 16578 IDGKKQSLRIVKAKPEDVGEYSV---QVGEQTSKAKLTVEEPLVDFVIRLPDITLATKTT 16634 Query: 218 SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLR---LDNVILADEGEYSCEA 274 F ++ P +V W + G P + +V +G++R + + D GE SC A Sbjct: 16635 DAEFTVQLS-QPDVEVTWCKK-GKPIKPNQKHEVFVEGTVRRLVIHDASDEDAGEISCVA 16692 Query: 275 ENSVGAVSASGYLTVYD---PPSINLSPN-SVNVESGNVARFTCTATGRPEPTMFWSVEG 330 EN V++S L V + PP I + ++ V+ + FT TG P P W+ Sbjct: 16693 EN----VTSSTKLCVEELKLPPVITSDKDQTIKVKENDDVTFTVKYTGVPTPEACWT--- 16745 Query: 331 NRTIIFPGMSR 341 R ++ P R Sbjct: 16746 TRKVVIPKSKR 16756 Score = 48.4 bits (110), Expect = 0.001 Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 5/101 (4%) Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA--ICTPEPIIAWYFEGEALIQNHRRNV 446 V DD PP P + + ++A F C I P + W+ G+AL R Sbjct: 5166 VPDDDTGKPPEFITSPFDMVIGENALAHFECRLQPINDPSMRVDWFHNGKALWAGSRIKT 5225 Query: 447 TNDGTLVLKDLD---KSDSGTYTCVASSRHGKYVWSGALLV 484 ND V+ ++ + DSG YTC A+++HG+ S L V Sbjct: 5226 INDFGFVILEIAGCYQRDSGLYTCKATNKHGEATVSCKLQV 5266 Score = 45.2 bits (102), Expect = 0.011 Identities = 31/92 (33%), Positives = 49/92 (53%), Gaps = 10/92 (10%) Query: 111 RLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQ 168 +LEP++ + +GD C+ G P P V W NG T++ SR L + G +L + Sbjct: 5733 KLEPQTVE--EGDPARF-CVRVTGHPRPRVMWLINGHTVVH--GSRYKLTNDGMFHLDVP 5787 Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKIHI 200 RQ D G+ + IARN+ G +IAT ++ + Sbjct: 5788 KTRQYDTGKVEVIARNSVG---ESIATTELKV 5816 Score = 45.2 bits (102), Expect = 0.011 Identities = 44/173 (25%), Positives = 72/173 (41%), Gaps = 12/173 (6%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 DV + TL+C GG P P + W K G + S RSI + + ++ Sbjct: 16773 DVVSELDKEVTLSCVFGGIPEPKVTWKKNGQVFES---RSIRYENRVAKYTIEKTTIETE 16829 Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK---QSAQGDTVVLECLPPRGSP 136 A Y C ATN G+A + + L L+++ LE E K Q + +++ RG P Sbjct: 16830 A-TYTCVATNEKGSAET-SCRLK---LQQKPVLEVEDKYLTQKLRTGSILTIPATVRGYP 16884 Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGT 188 +P V W K + + ++ + +G+Y+ A N +GT Sbjct: 16885 QPTVTWHKETIEQKTTKSVTIETTETTSTYTVKKVTREQSGKYKVTATNESGT 16937 Score = 44.8 bits (101), Expect = 0.015 Identities = 27/107 (25%), Positives = 48/107 (44%), Gaps = 6/107 (5%) Query: 379 GSSFVRGKLT-VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437 G ++V LT V + D PP+ N A+F P+P + W +G Sbjct: 1792 GGAYVPPSLTHVYAQGDISPPVFEQIFKNARFAQGGNALFEGRLRGNPKPFVTWTRKGAP 1851 Query: 438 LIQNHR-----RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479 L+++ + T D +L++ + D G YTC A +++G+ + S Sbjct: 1852 LLESQKFRMSYNEATGDVSLLINQIGPGDEGEYTCTARNQYGEAICS 1898 Score = 44.8 bits (101), Expect = 0.015 Identities = 49/160 (30%), Positives = 64/160 (40%), Gaps = 13/160 (8%) Query: 37 GSPSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTAR 95 G S I W Y G VL S R+I A G L ++ D G Y C ATN +GTA Sbjct: 4693 GDQSMVIEWFYNGKVLEASHRVRTIY-AFGTVALEVLGTKIE-DTGTYTCRATNKHGTAE 4750 Query: 96 -SRNATLHVAVLREEFRLEPESKQ---SAQGDTVVLEC-LPPRGSPEPNVYWKKNGQTLL 150 S N ++ R + G + EC L P P+ V W NG+ L Sbjct: 4751 ISCNLECVDKPRGQKPRFTSHIQPLEGLKDGQSAHFECTLIPVNDPDLKVEWYHNGK--L 4808 Query: 151 FDGDSRMHLVDGGNLVIQD---ARQTDAGRYQCIARNAAG 187 +R+ V V+ D + D+G Y C A N G Sbjct: 4809 MRHSNRIKTVSDFGYVVLDISYLQDHDSGEYVCRAWNKYG 4848 Score = 44.0 bits (99), Expect = 0.025 Identities = 34/113 (30%), Positives = 51/113 (45%), Gaps = 12/113 (10%) Query: 428 IIAWYFEGEALIQNHR-RNVTNDGTLVLKDLDKS--DSGTYTCVASSRHGKYVWSGAL-L 483 +I W++ G+ L +HR R + GT+ L+ L D+GTYTC A+++HG S L Sbjct: 4698 VIEWFYNGKVLEASHRVRTIYAFGTVALEVLGTKIEDTGTYTCRATNKHGTAEISCNLEC 4757 Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITH------NVTDTSVTLSWSQNNKI 530 VD P F + + L G H V D + + W N K+ Sbjct: 4758 VDKPRGQKPRF--TSHIQPLEGLKDGQSAHFECTLIPVNDPDLKVEWYHNGKL 4808 Score = 43.2 bits (97), Expect = 0.044 Identities = 26/88 (29%), Positives = 37/88 (42%), Gaps = 4/88 (4%) Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAG----GGNMPLGRVKVLDDGSLRLDNVILADEGEYS 271 G + F+ R+ G+P P V W R + + D SL ++ + DEGEY+ Sbjct: 1826 GGNALFEGRLRGNPKPFVTWTRKGAPLLESQKFRMSYNEATGDVSLLINQIGPGDEGEYT 1885 Query: 272 CEAENSVGAVSASGYLTVYDPPSINLSP 299 C A N G S Y+ P L P Sbjct: 1886 CTARNQYGEAICSVYIQPEGAPMPALQP 1913 Score = 43.2 bits (97), Expect = 0.044 Identities = 24/89 (26%), Positives = 39/89 (43%), Gaps = 3/89 (3%) Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAG--GSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 +G+ P I P D+ + + A CR PS + W+ G + + + + G Sbjct: 5171 TGKPPEFITSPFDMVIGENALAHFECRLQPINDPSMRVDWFHNGKALWAGSRIKTINDFG 5230 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTA 94 L G D+G+Y C+ATN +G A Sbjct: 5231 FVILEIA-GCYQRDSGLYTCKATNKHGEA 5258 Score = 42.7 bits (96), Expect = 0.059 Identities = 46/184 (25%), Positives = 73/184 (39%), Gaps = 21/184 (11%) Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372 +C G PEP + W G +F S +Y + V TI T ++ T C Sbjct: 16785 SCVFGGIPEPKVTWKKNGQ---VFESRSI-RYE-----NRVAKYTIEKTTI-ETEATYTC 16834 Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432 A N GS+ +L + +P + + Q L S+ P T P+P + W+ Sbjct: 16835 VATNEKGSAETSCRLKL---QQKPVLEVEDKYLTQKLRTGSILTIPATVRGYPQPTVTWH 16891 Query: 433 FEGEALIQNHRRNVT-----NDGTLVLKDLDKSDSGTYTCVASSRHG-KYVWSGALLVDS 486 E + Q ++VT T +K + + SG Y A++ G YV ++D Sbjct: 16892 --KETIEQKTTKSVTIETTETTSTYTVKKVTREQSGKYKVTATNESGTTYVECTVQVIDK 16949 Query: 487 PINP 490 P P Sbjct: 16950 PSRP 16953 Score = 42.3 bits (95), Expect = 0.078 Identities = 42/200 (21%), Positives = 74/200 (37%), Gaps = 4/200 (2%) Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 PP+ + P + V+ C PEP + W+ G + + + Sbjct: 16056 PPTFSKKPKAQYVDENTNVILECRLVAVPEPDIVWTFNGEDIDEEEIKNVRIVTESDMHM 16115 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411 +V+ I+ K+ T A N G + + L V + D P I+ N + Sbjct: 16116 YCSVVHISKVKKSQE-GTYEVIATNREGEARLPITLKVRTTDKEAPQIL-EPLRNMVIRE 16173 Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471 V + P P + WY +G+ + + ++ + TL L KS+ G YT A + Sbjct: 16174 GESVVLSTQIVGNPPPKVTWYKDGKPV--KNAKSDKDLHTLTLITPQKSEKGEYTVKAVN 16231 Query: 472 RHGKYVWSGALLVDSPINPN 491 G + L ++ P N Sbjct: 16232 PLGSVETTANLTIEEPAGGN 16251 Score = 39.9 bits (89), Expect = 0.41 Identities = 34/130 (26%), Positives = 55/130 (42%), Gaps = 7/130 (5%) Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT-VTSDDDRPPPIITNGPSNQTLP 410 G L + T D+ T C A N G++ + L V + P ++ + L Sbjct: 4721 GTVALEVLGTKIEDT-GTYTCRATNKHGTAEISCNLECVDKPRGQKPRFTSHIQPLEGLK 4779 Query: 411 IKSMAVFPCTAICTPEPI--IAWYFEGEALIQNHRRNVTNDGTLVLKD---LDKSDSGTY 465 A F CT I +P + WY G+ + ++R +D V+ D L DSG Y Sbjct: 4780 DGQSAHFECTLIPVNDPDLKVEWYHNGKLMRHSNRIKTVSDFGYVVLDISYLQDHDSGEY 4839 Query: 466 TCVASSRHGK 475 C A +++G+ Sbjct: 4840 VCRAWNKYGE 4849 Score = 39.5 bits (88), Expect = 0.55 Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 6/92 (6%) Query: 389 VTSDDDRPPPIITNG-PSNQTLPIKSMAVFPCTAICTPEPI--IAWYFEGEALIQNHRRN 445 VT D+ PP T N +P F C +P I W++ G + R + Sbjct: 5303 VTEDEQPNPPKFTEEIKDNLDVPEGGPIHFDCRVEPVGDPTMRIEWFYNGHVMATGSRVH 5362 Query: 446 VTNDGTLVLKDLD---KSDSGTYTCVASSRHG 474 ND + D+D DSG YTC A+++ G Sbjct: 5363 QLNDFGFIALDVDYIYARDSGEYTCRATNKWG 5394 Score = 39.5 bits (88), Expect = 0.55 Identities = 47/190 (24%), Positives = 70/190 (36%), Gaps = 17/190 (8%) Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369 A+F G P PT+ W E FP + F G ++L I DS Sbjct: 6047 AKFEVEFEGEPNPTVKWYRES-----FPIQNSPDLQIHT-FSGKSILIIRQVFVEDSA-V 6099 Query: 370 IVCSAVNYAGSSFVRGKLTVTS------DDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423 C A N G++ L V +PP +T S T+ +A F Sbjct: 6100 FSCVAENRGGTAKCSANLVVEERRRAGKGGIQPPSFVTTIQST-TVATGQLARFDAKVTG 6158 Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480 T + W G + + + + + TL++ + DSG Y CVA + G+ G Sbjct: 6159 TRPLDVYWLKNGMKIQPSIKFKMLEEDSVHTLLIIEPFAEDSGRYECVAVNAAGEARCDG 6218 Query: 481 ALLVDSPINP 490 +V SP P Sbjct: 6219 DCIVQSPSKP 6228 Score = 39.1 bits (87), Expect = 0.72 Identities = 32/137 (23%), Positives = 55/137 (40%), Gaps = 7/137 (5%) Query: 196 LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255 L+ I P T + G+ V+ + G P P++ ++ GG ++ + Sbjct: 971 LRREIAPRFTTPLSGKIVDQGADVSMEAIYDGFPSPEIKVEKN-GGQLFEDAHTRISNKC 1029 Query: 256 S---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLSPNSVNVESGNV 309 + + L V + D G Y+ A N+VG +++ L V PP + + G Sbjct: 1030 NRVTIELKQVGVGDAGRYAVTASNTVGQSTSTADLVVKKTIFPPVFGRRLQAQVSKKGEK 1089 Query: 310 ARFTCTATGRPEPTMFW 326 TG PEPT+ W Sbjct: 1090 LTMEVEVTGLPEPTVTW 1106 Score = 39.1 bits (87), Expect = 0.72 Identities = 20/66 (30%), Positives = 35/66 (53%), Gaps = 3/66 (4%) Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL---DKSDSGTYTCVASSRHGKY 476 T I P+ ++ WYF G+ L HR +D +V+ D+ + +SG Y A +++G+ Sbjct: 4924 TPITDPDLVVEWYFNGKKLPHGHRFRTFHDFGIVILDILYCYEENSGVYEARARNKYGED 4983 Query: 477 VWSGAL 482 V +L Sbjct: 4984 VTRASL 4989 Score = 39.1 bits (87), Expect = 0.72 Identities = 29/101 (28%), Positives = 43/101 (42%), Gaps = 8/101 (7%) Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363 VE G+ ARF TG P P + W + G+ + +Y T DG+ L + T + Sbjct: 5739 VEEGDPARFCVRVTGHPRPRVMWLINGHTVV-----HGSRYKLTN--DGMFHLDVPKTRQ 5791 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404 D+ V A N G S +L V + D ++ N P Sbjct: 5792 YDTGKVEVI-ARNSVGESIATTELKVVARSDDYRNVLKNSP 5831 Score = 38.3 bits (85), Expect = 1.3 Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 5/89 (5%) Query: 392 DDDRPPPIITNGPSNQTLPIKSMAVFPC--TAICTPEPIIAWYFEGEALIQNHRRNVTND 449 D +PP +T TL ++ F C + P + W+F G+ L+ +R D Sbjct: 5585 DRKQPPRFVTQIKEQLTLTEMAVTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFQPIYD 5644 Query: 450 GTLVLKDLD---KSDSGTYTCVASSRHGK 475 V + DSG Y C A++ +GK Sbjct: 5645 FGYVAMNFGWVYPEDSGEYVCRATNLYGK 5673 Score = 37.9 bits (84), Expect = 1.7 Identities = 28/79 (35%), Positives = 38/79 (48%), Gaps = 8/79 (10%) Query: 216 GSSVTFQCRVG--GDPLPDVLWRRSAGGGNMPLG-RVKVLDDG---SLRLDNVILADEGE 269 G + F CRV GDP + W + G M G RV L+D +L +D + D GE Sbjct: 5327 GGPIHFDCRVEPVGDPTMRIEWFYN--GHVMATGSRVHQLNDFGFIALDVDYIYARDSGE 5384 Query: 270 YSCEAENSVGAVSASGYLT 288 Y+C A N G + S +T Sbjct: 5385 YTCRATNKWGTATTSAKVT 5403 Score = 37.5 bits (83), Expect = 2.2 Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 8/117 (6%) Query: 86 EATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWK 143 ++ N+ RS +++ + + EF+ KQ + + EC+ +G P P V+W Sbjct: 738 KSVNAPENRRSSQSSVEIIERHQCPEFKELFSDKQGEIDEVIKFECIV-KGKPTPKVHWF 796 Query: 144 KNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198 N Q + G + + G L IQ G+ C+A N AG + + +A L I Sbjct: 797 FNDQPV--HGHNFLVSTSGERQVLTIQKLTHDAVGKISCVAENEAG-KATCVAFLNI 850 Score = 37.5 bits (83), Expect = 2.2 Identities = 30/131 (22%), Positives = 65/131 (49%), Gaps = 10/131 (7%) Query: 157 MHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVV-AQT 215 + ++ +L+++ ++ + Q + ++ R S ++I+P +T P+ + + Sbjct: 3016 VRIIAKNDLILETQNESGLQKIQYL-EDSTRHRRSEFVDEVVNIRPRFLTHPKSLTNTRE 3074 Query: 216 GSSVTFQCRVGG--DPLPDVLWRRSAGGGNMPLG-RVKVLDD-GSLRLD--NVILADEGE 269 G F+C++ DP V W ++ G + +G R + + D G + LD ++I D G Sbjct: 3075 GGHAHFECKIEPVTDPNLKVEWFKN--GRPITVGHRFRPIHDFGYVALDIVHLIAEDSGV 3132 Query: 270 YSCEAENSVGA 280 Y+C A N +G+ Sbjct: 3133 YTCRAVNLIGS 3143 Score = 37.5 bits (83), Expect = 2.2 Identities = 26/98 (26%), Positives = 40/98 (40%), Gaps = 5/98 (5%) Query: 392 DDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI--IAWYFEGEALIQNHRRNVTND 449 + + P+ T N + A F C I +P + WY L R TN+ Sbjct: 3188 ESTKQAPVFTTSLKNVEIKENQRAHFECRLIPVSDPSMRVEWYHNNLPLKSGSRFTETNN 3247 Query: 450 GTLVLKDLDKS---DSGTYTCVASSRHGKYVWSGALLV 484 V D+ + D+GTYTC A + G+ + S +V Sbjct: 3248 FGFVALDIMSTLPEDAGTYTCRAYNAVGEAITSAVAVV 3285 Score = 37.5 bits (83), Expect = 2.2 Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 3/65 (4%) Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLV---LKDLDKSDSGTYTCVASSRHGKYVWSGA 481 P+ + W G+ + ++R +D V +K ++ DSGTYTC A + G+ V S + Sbjct: 3356 PKLTVEWLRNGQPIEASNRTTTMHDFGYVALNMKYVNPEDSGTYTCRAVNELGQAVTSAS 3415 Query: 482 LLVDS 486 L+V S Sbjct: 3416 LIVQS 3420 Score = 37.5 bits (83), Expect = 2.2 Identities = 30/95 (31%), Positives = 40/95 (42%), Gaps = 3/95 (3%) Query: 197 KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS 256 K KP ++ E + G F RV G P P V+W + G + R K+ +DG Sbjct: 5723 KPRTKPVFVSKLEPQTVEEGDPARFCVRVTGHPRPRVMWLIN-GHTVVHGSRYKLTNDGM 5781 Query: 257 LRLD--NVILADEGEYSCEAENSVGAVSASGYLTV 289 LD D G+ A NSVG A+ L V Sbjct: 5782 FHLDVPKTRQYDTGKVEVIARNSVGESIATTELKV 5816 Score = 37.1 bits (82), Expect = 2.9 Identities = 30/103 (29%), Positives = 43/103 (41%), Gaps = 6/103 (5%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVG--GDPLPDVLWRRSAGGGNMPLGRVKVLDDGS--- 256 P IT P D+V + F+CR+ DP V W + G R+K ++D Sbjct: 5175 PEFITSPFDMVIGENALAHFECRLQPINDPSMRVDWFHN-GKALWAGSRIKTINDFGFVI 5233 Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299 L + D G Y+C+A N G + S L V I + P Sbjct: 5234 LEIAGCYQRDSGLYTCKATNKHGEATVSCKLQVKGRQGIVMEP 5276 Score = 36.3 bits (80), Expect = 5.1 Identities = 25/71 (35%), Positives = 32/71 (45%), Gaps = 4/71 (5%) Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG---NLVIQDARQTDAG 176 AQG + E RG+P+P V W + G LL RM + +L+I D G Sbjct: 1824 AQGGNALFEGRL-RGNPKPFVTWTRKGAPLLESQKFRMSYNEATGDVSLLINQIGPGDEG 1882 Query: 177 RYQCIARNAAG 187 Y C ARN G Sbjct: 1883 EYTCTARNQYG 1893 Score = 36.3 bits (80), Expect = 5.1 Identities = 38/148 (25%), Positives = 61/148 (41%), Gaps = 8/148 (5%) Query: 14 IIEQPLDVT--VARHQPATLNCRA--GGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 + QPL + HQ A R G P+ + WY+ ++ + + G L Sbjct: 3993 VFTQPLQNIDRINEHQTAHFEARLIPVGDPNLKVEWYRNEKIIEDSSRITKQHDFGFVSL 4052 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 +H R D GVY C A N G A + A++ V V +++ + S + + Sbjct: 4053 DISHIR-KEDEGVYMCRAVNPLGEAVT-TASMRV-VSEASIQMDTQHPDSISRIHQLEKP 4109 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRM 157 L PR + EP ++K T L G S + Sbjct: 4110 LAPRPT-EPERLFEKPIFTQLLTGPSEL 4136 Score = 36.3 bits (80), Expect = 5.1 Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 4/90 (4%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRV--GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL 259 P IT ++ + +V F+C V DP + W + + D G L Sbjct: 4390 PVFITHLNNIECKESDNVRFECNVEPARDPTMSIEWFYNGQPLQAAAKFKSIYDFGYCAL 4449 Query: 260 D--NVILADEGEYSCEAENSVGAVSASGYL 287 D N + G Y+C+A NS G+ + SG L Sbjct: 4450 DLTNSYAENSGVYTCKATNSKGSATTSGTL 4479 Score = 36.3 bits (80), Expect = 5.1 Identities = 24/83 (28%), Positives = 33/83 (39%), Gaps = 4/83 (4%) Query: 395 RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGT 451 +PP I Q +P + V C P P I WYF L + + +T Sbjct: 8088 KPPRITEKLRPRQCVP-EEPTVLECKVEGVPFPEIKWYFNDILLFASEKYEITVMEQVAK 8146 Query: 452 LVLKDLDKSDSGTYTCVASSRHG 474 L + + SD G YTC A + G Sbjct: 8147 LKIAKVTPSDVGVYTCEAKNEAG 8169 Score = 36.3 bits (80), Expect = 5.1 Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 3/90 (3%) Query: 10 EAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI-LPAGGLF 67 E+P +E+ + V V + L C+ G P+P + WY + + +I G+ Sbjct: 8487 ESPRFVEELVQPVEVMDGEALLLTCQVTGKPTPKVEWYHNAEKITENKETTISQDLQGVC 8546 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSR 97 L+ T ++ G Y C ATN G + S+ Sbjct: 8547 QLQITEVFPENE-GQYECVATNKIGKSVSK 8575 Score = 35.9 bits (79), Expect = 6.7 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 3/68 (4%) Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDK---SDSGTYTCVASSRHGKYVWSGA 481 P I WYF G+ L R +T++ V D+ + D G YTC A ++ G+ S Sbjct: 4558 PNLFIEWYFNGKMLNHGSRFKMTSEFGFVTMDMIEVYARDQGIYTCKAYNKAGEAFTSTT 4617 Query: 482 LLVDSPIN 489 + S N Sbjct: 4618 IFCSSKEN 4625 Score = 35.5 bits (78), Expect = 8.9 Identities = 29/87 (33%), Positives = 39/87 (44%), Gaps = 5/87 (5%) Query: 121 QGDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGR 177 +G V+LE + PR P + W KNG +L G D G L I R D+ Sbjct: 4272 EGQHVLLEAQVEPRADPNLRIEWFKNGISLT-TGSRIRSTFDFGLVTLSINGLRADDSAI 4330 Query: 178 YQCIARNAAGTRESAIATLKIHIKPYL 204 Y C A N G S ++LKI + +L Sbjct: 4331 YTCKATNQVGEAVST-SSLKIEDRHWL 4356 Score = 35.5 bits (78), Expect = 8.9 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 7/90 (7%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIR--WYKGGVLVVSD-THRSILPAGGLFF 68 P Q VTV + C+ P++R WY+ G + S +R+I G + Sbjct: 5447 PKFTTQITSVTVDEAEAVRFECQVEPKTDPSLRVEWYRNGKPLPSGHRYRNIFDMGFVSL 5506 Query: 69 -LRATHGRVHSDAGVYWCEATNSYGTARSR 97 + +G D+G Y C A N+YG R+R Sbjct: 5507 DILYVYGE---DSGEYVCRAINNYGEDRTR 5533 >UniRef50_Q4TBR4 Cluster: Chromosome undetermined SCAF7099, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome undetermined SCAF7099, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1000 Score = 110 bits (264), Expect = 3e-22 Identities = 75/256 (29%), Positives = 115/256 (44%), Gaps = 9/256 (3%) Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195 P +V W KN +++ + G L + R++D+G Y CIA N G + Sbjct: 32 PPADVTWTKNNHPIMYYDPRYVTQAQGQMLTVPHVRESDSGEYCCIATNGVGEPAKSCGA 91 Query: 196 LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255 L++ +KP + P ++ S C G+P PDV W + + RV +LD G Sbjct: 92 LQLKMKPQIKRHPTNLTLLVESKAVLPCVTLGNPKPDVTWLKDDELIKIS-DRVTILDYG 150 Query: 256 SLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314 +L++ NV D G+Y C A NS G ++S + V P I P V G + C Sbjct: 151 ALKIHNVRKEDAGQYRCVARNSFGLSISKPVTIEVQVPARILQVPKESKVAYGGLVSLQC 210 Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374 ATG P PT+ W GN TI G S D+ + V V + ++ + T + S Sbjct: 211 NATGNPVPTITWLENGN-TI--SGASVDEALSGDVIQSVLKVRVS----KPALYTCLASN 263 Query: 375 VNYAGSSFVRGKLTVT 390 + AG++ V+ VT Sbjct: 264 RHSAGANTVKASARVT 279 Score = 100 bits (239), Expect = 3e-19 Identities = 77/283 (27%), Positives = 125/283 (44%), Gaps = 10/283 (3%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 AP II + V AT C P + W K ++ R + A G L Sbjct: 4 APRIITLLETLDVLTDHNATFICEVESRPPADVTWTKNNHPIMYYDPRYVTQAQGQM-LT 62 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130 H R SD+G Y C ATN G L + ++ + + P + VL C+ Sbjct: 63 VPHVR-ESDSGEYCCIATNGVGEPAKSCGALQLK-MKPQIKRHPTNLTLLVESKAVLPCV 120 Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190 G+P+P+V W K+ + + R+ ++D G L I + R+ DAG+Y+C+ARN+ G Sbjct: 121 T-LGNPKPDVTWLKDDELIKIS--DRVTILDYGALKIHNVRKEDAGQYRCVARNSFGLSI 177 Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250 S T+++ + ++ P++ G V+ QC G+P+P + W + + Sbjct: 178 SKPVTIEVQVPARILQVPKESKVAYGGLVSLQCNATGNPVPTITWLENGNTISGASVDEA 237 Query: 251 VLDDGSLRLDNVILADEGEYSCEAEN--SVGA--VSASGYLTV 289 + D + V ++ Y+C A N S GA V AS +TV Sbjct: 238 LSGDVIQSVLKVRVSKPALYTCLASNRHSAGANTVKASARVTV 280 Score = 63.7 bits (148), Expect = 3e-08 Identities = 71/275 (25%), Positives = 106/275 (38%), Gaps = 17/275 (6%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLD 260 P +IT E + T + TF C V P DV W ++ R G L + Sbjct: 5 PRIITLLETLDVLTDHNATFICEVESRPPADVTWTKNNHPIMYYDPRYVTQAQGQMLTVP 64 Query: 261 NVILADEGEYSCEAENSVGAVSAS-GYLTVYDPPSINLSPNSVNVESGNVARFTCTATGR 319 +V +D GEY C A N VG + S G L + P I P ++ + + A C G Sbjct: 65 HVRESDSGEYCCIATNGVGEPAKSCGALQLKMKPQIKRHPTNLTLLVESKAVLPCVTLGN 124 Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379 P+P + W + I ++ Y A L I++ K D+ C A N G Sbjct: 125 PKPDVTWLKDDELIKISDRVTILDYGA---------LKIHNVRKEDA-GQYRCVARNSFG 174 Query: 380 SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI 439 S + VT + P I+ P + + C A P P I W G + Sbjct: 175 LSISK---PVTIEVQVPARIL-QVPKESKVAYGGLVSLQCNATGNPVPTITWLENGNTIS 230 Query: 440 -QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473 + ++ D + + S YTC+AS+RH Sbjct: 231 GASVDEALSGDVIQSVLKVRVSKPALYTCLASNRH 265 Score = 63.7 bits (148), Expect = 3e-08 Identities = 60/246 (24%), Positives = 107/246 (43%), Gaps = 19/246 (7%) Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352 P I +++V + + A F C RP + W+ + N I++ +Y A Sbjct: 5 PRIITLLETLDVLTDHNATFICEVESRPPADVTWT-KNNHPIMYYD---PRYVTQAQGQM 60 Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR-GKLTVTSDDDRPPPIITNGPSNQTLPI 411 +TV + ++D + C A N G G L + + P I P+N TL + Sbjct: 61 LTVPHVRESDSGE----YCCIATNGVGEPAKSCGALQL-----KMKPQIKRHPTNLTLLV 111 Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471 +S AV PC + P+P + W + E + + R + + G L + ++ K D+G Y CVA + Sbjct: 112 ESKAVLPCVTLGNPKPDVTWLKDDELIKISDRVTILDYGALKIHNVRKEDAGQYRCVARN 171 Query: 472 RHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSV-TLSWSQN-NK 529 G + S + ++ + I + S + + N T V T++W +N N Sbjct: 172 SFGLSI-SKPVTIEVQVPARI--LQVPKESKVAYGGLVSLQCNATGNPVPTITWLENGNT 228 Query: 530 IGSSSI 535 I +S+ Sbjct: 229 ISGASV 234 >UniRef50_Q0E8J3 Cluster: CG33484-PD, isoform D; n=9; Sophophora|Rep: CG33484-PD, isoform D - Drosophila melanogaster (Fruit fly) Length = 3651 Score = 110 bits (264), Expect = 3e-22 Identities = 117/420 (27%), Positives = 184/420 (43%), Gaps = 48/420 (11%) Query: 119 SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGR 177 S +GD V EC G+PEP V W K+G ++ + D + G LVI++ D+ R Sbjct: 1388 SREGDRFVFEC-EVTGTPEPAVEWFKDGISIQTNSDYKTTFDKGICRLVIEETFAADSAR 1446 Query: 178 YQCIARNAAGTRESAIATLKIH--------IKPYLITGPEDVVAQTGSSVTFQCRVGGDP 229 + C A N GT ++ ATL + + P ++ + A GSS F C V G P Sbjct: 1447 FSCRASNLVGTCDTN-ATLSVRENAAEVQLVPPRILRFLQSGKATEGSSFQFACVVAGVP 1505 Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYL 287 LP V W ++ + V ++G +L+ + V L D+ Y+C A N G S L Sbjct: 1506 LPTVQWFKNDKCIDDSPDYVISYNNGEATLKFEEVFLEDDAVYTCSASNPAGIEHCSASL 1565 Query: 288 TV--YDP---PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRD 342 V +P PS + ++ G + G P P ++W G P RD Sbjct: 1566 IVEPLEPTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWLHNGK-----PFQPRD 1620 Query: 343 KYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF------VRGKL-TVTSDDDR 395 + G L I ND+ + V SA N AG ++ V+G+L TSD + Sbjct: 1621 SKYEY----GRVTLIIPQAYPNDA-GSYVLSAKNLAGEAYTSCNVIVKGRLPNETSDSEM 1675 Query: 396 PPPIITNGPSNQTLPIKSMAVFP-------CTAICTPEPIIAWYFEGEALIQNHRRNVTN 448 I P+ LP+K +++F C + PEP + WY + ++ + Sbjct: 1676 ASDIEPIKPAVH-LPLKDVSIFEGKPVRLDCVIVGQPEPEVIWYHNERPVKESADVQLLF 1734 Query: 449 DG---TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRA-ADVSSLP 504 G +L+++++ + D+G Y VA + G+ S L V +P+N RA A+ SLP Sbjct: 1735 QGDRCSLIIQEVYQEDAGHYKVVAINSAGEASSSCELKV-TPLNQAEPATRAQAERQSLP 1793 Score = 87.4 bits (207), Expect = 2e-15 Identities = 105/435 (24%), Positives = 172/435 (39%), Gaps = 43/435 (9%) Query: 14 IIEQPLDVTVARHQPA-TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRAT 72 + +PL V+R C G+P PA+ W+K G+ + +++ G+ L Sbjct: 1378 LFTRPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTFDKGICRL-VI 1436 Query: 73 HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-------ESKQSAQGDTV 125 +D+ + C A+N GT + NATL V E +L P +S ++ +G + Sbjct: 1437 EETFAADSARFSCRASNLVGTCDT-NATLSVRENAAEVQLVPPRILRFLQSGKATEGSSF 1495 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARN 184 C+ G P P V W KN + + D + +G L ++ D Y C A N Sbjct: 1496 QFACVVA-GVPLPTVQWFKNDKCIDDSPDYVISYNNGEATLKFEEVFLEDDAVYTCSASN 1554 Query: 185 AAGTRESAIATLKIHIKPYLITG---P-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 AG + + + ++P + P + +A+ G + + VGG P P+V W + Sbjct: 1555 PAGIEHCSASLIVEPLEPTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWLHNGK 1614 Query: 241 -----GGNMPLGRVKVL-------DDGSLRLDNVILADEGEYSCEA---ENSVGAVSASG 285 GRV ++ D GS L LA E SC S S Sbjct: 1615 PFQPRDSKYEYGRVTLIIPQAYPNDAGSYVLSAKNLAGEAYTSCNVIVKGRLPNETSDSE 1674 Query: 286 YLTVYDP--PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDK 343 + +P P+++L V++ G R C G+PEP + W R + ++ Sbjct: 1675 MASDIEPIKPAVHLPLKDVSIFEGKPVRLDCVIVGQPEPEVIW-YHNERPV------KES 1727 Query: 344 YHATAVFDGVTV-LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN 402 +F G L I + + D+ + V A+N AG + +L VT + P Sbjct: 1728 ADVQLLFQGDRCSLIIQEVYQEDAGHYKVV-AINSAGEASSSCELKVTPLNQAEPATRAQ 1786 Query: 403 GPSNQTLPIKSMAVF 417 Q+LP S F Sbjct: 1787 A-ERQSLPKDSQPKF 1800 Score = 66.9 bits (156), Expect = 3e-09 Identities = 77/322 (23%), Positives = 114/322 (35%), Gaps = 24/322 (7%) Query: 204 LITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL--D 260 L T P +D V++ G F+C V G P P V W + D G RL + Sbjct: 1378 LFTRPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTFDKGICRLVIE 1437 Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVYD--------PPSINLSPNSVNVESGNVARF 312 AD +SC A N VG + L+V + PP I S G+ +F Sbjct: 1438 ETFAADSARFSCRASNLVGTCDTNATLSVRENAAEVQLVPPRILRFLQSGKATEGSSFQF 1497 Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372 C G P PT+ W + ++ I S D + + +G L + D C Sbjct: 1498 ACVVAGVPLPTVQW-FKNDKCI---DDSPD--YVISYNNGEATLKFEEVFLEDDA-VYTC 1550 Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432 SA N AG L V + P SN + P P + W Sbjct: 1551 SASNPAGIEHCSASLIVEPLEPTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWL 1610 Query: 433 FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPI-NPN 491 G+ + TL++ +D+G+Y A + G+ S ++V + N Sbjct: 1611 HNGKPFQPRDSKYEYGRVTLIIPQAYPNDAGSYVLSAKNLAGEAYTSCNVIVKGRLPNET 1670 Query: 492 IHFFRAADVSSLPGPPTKPITH 513 A+D+ P KP H Sbjct: 1671 SDSEMASDIE-----PIKPAVH 1687 Score = 62.1 bits (144), Expect = 9e-08 Identities = 48/159 (30%), Positives = 74/159 (46%), Gaps = 6/159 (3%) Query: 37 GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96 G PSP I+ K G + D H I + V DAG Y A+N+ G + S Sbjct: 2154 GFPSPEIKVEKNGGQLFEDAHTRISNKCNRVTIELKQVGV-GDAGRYAVTASNTVGQSTS 2212 Query: 97 R-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155 + + + F +++ S +G+ + +E + G PEP V W K+ + L G S Sbjct: 2213 TADLVVKKTIFPPVFGRRLQAQVSKKGEKLTME-VEVTGLPEPTVTWLKDDKPLKDAGIS 2271 Query: 156 RMHLVDGGN---LVIQDARQTDAGRYQCIARNAAGTRES 191 L+ GN L+I+ A+ TD+G+Y A NA G +S Sbjct: 2272 EHRLLAQGNSYRLIIEKAQTTDSGKYMVRATNAGGEAKS 2310 Score = 48.4 bits (110), Expect = 0.001 Identities = 31/93 (33%), Positives = 44/93 (47%), Gaps = 6/93 (6%) Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD--DG--S 256 +P IT +D+ G + F+C V P P V W + GG + G ++ +G Sbjct: 3552 QPLFITPLKDIAVGVGGTARFECIVQAHPQPQVNWTHN--GGLLESGSRHCIEYRNGVCR 3609 Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 L L D G Y+C A N +GA + SG LTV Sbjct: 3610 LTLPQAYPDDNGSYACTAINPLGAATTSGNLTV 3642 Score = 41.1 bits (92), Expect = 0.18 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 7/90 (7%) Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361 + V G ARF C P+P + W+ G + SR H +GV LT+ Sbjct: 3562 IAVGVGGTARFECIVQAHPQPQVNWTHNGG---LLESGSR---HCIEYRNGVCRLTLPQA 3615 Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTS 391 +D+ + C+A+N G++ G LTV+S Sbjct: 3616 YPDDN-GSYACTAINPLGAATTSGNLTVSS 3644 Score = 39.1 bits (87), Expect = 0.72 Identities = 32/137 (23%), Positives = 55/137 (40%), Gaps = 7/137 (5%) Query: 196 LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255 L+ I P T + G+ V+ + G P P++ ++ GG ++ + Sbjct: 2123 LRREIAPRFTTPLSGKIVDQGADVSMEAIYDGFPSPEIKVEKN-GGQLFEDAHTRISNKC 2181 Query: 256 S---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLSPNSVNVESGNV 309 + + L V + D G Y+ A N+VG +++ L V PP + + G Sbjct: 2182 NRVTIELKQVGVGDAGRYAVTASNTVGQSTSTADLVVKKTIFPPVFGRRLQAQVSKKGEK 2241 Query: 310 ARFTCTATGRPEPTMFW 326 TG PEPT+ W Sbjct: 2242 LTMEVEVTGLPEPTVTW 2258 Score = 37.5 bits (83), Expect = 2.2 Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 8/117 (6%) Query: 86 EATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWK 143 ++ N+ RS +++ + + EF+ KQ + + EC+ +G P P V+W Sbjct: 1890 KSVNAPENRRSSQSSVEIIERHQCPEFKELFSDKQGEIDEVIKFECIV-KGKPTPKVHWF 1948 Query: 144 KNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198 N Q + G + + G L IQ G+ C+A N AG + + +A L I Sbjct: 1949 FNDQPV--HGHNFLVSTSGERQVLTIQKLTHDAVGKISCVAENEAG-KATCVAFLNI 2002 >UniRef50_UPI00015B41E3 Cluster: PREDICTED: similar to fasciclin ii (fas ii); n=1; Nasonia vitripennis|Rep: PREDICTED: similar to fasciclin ii (fas ii) - Nasonia vitripennis Length = 772 Score = 109 bits (263), Expect = 3e-22 Identities = 107/415 (25%), Positives = 174/415 (41%), Gaps = 30/415 (7%) Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139 AG Y C T + S+ + ++ + P ++ G+ ++C R P P Sbjct: 116 AGQYICRGTYANTELLSKTVIIET-IVAITWDDAPLNQFPILGEDFAIKC-QVRARPSPK 173 Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR-NAAGTRESAIATLKI 198 V W NG+ + + ++++ L I++ +++D G Y C A G + +++ Sbjct: 174 VDWLFNGEVIRTNDH---YVIETHALRIKNVKESDDGIYTCRASVEQTGELQERAIRVEV 230 Query: 199 HIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDD-G 255 H +P ++ V T G S C+ G P P W ++ N+ + R V +D G Sbjct: 231 HTRPSIVEAENSVYEVTEGESAQILCKGTGKPPPKFTWIKTLTKENLAVTDRFSVNEDTG 290 Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315 L + NV D GEY C A N+ G + + V P I N + G +C Sbjct: 291 LLTISNVKRDDSGEYQCTATNAAGMAIMNIQVNVIVKPKIMEFLNQ-TIAQGEKTVLSCK 349 Query: 316 ATGRPEPTMFWSVEGNRTIIFPGM--SRDKYHATAVFD---GVTV--LTINDTDKNDSRN 368 A G+P PT+ + + G+ D+ H T FD G TV LTI+ T ++D Sbjct: 350 AFGKPPPTITFRKHTSEKPFIRGVQPEDDRIHLTNDFDDQQGETVGNLTIDHTLRSDD-G 408 Query: 369 TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPE 426 C A N G +F G LTV + PP + SN+T+ C A P Sbjct: 409 LYECIANNKGGMAFKNGHLTV----EFPPSFAS--MSNRTIYSWDNRPVNLTCIAESIPN 462 Query: 427 PIIAWYFEGEALIQNHRRNVTND----GTLVLKDLDKSDSGTYTCVASSRHGKYV 477 I W + G ++N ++ D +L +K LD+ Y C A +R G+ + Sbjct: 463 ATIHWTYYGNDKVENDQQITVYDNGPISSLYIKPLDRRYYTQYKCHAKNRLGEAI 517 Score = 100 bits (239), Expect = 3e-19 Identities = 84/334 (25%), Positives = 137/334 (41%), Gaps = 26/334 (7%) Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75 + PL+ + + C+ PSP + W G ++ ++ H I LR + + Sbjct: 147 DAPLNQFPILGEDFAIKCQVRARPSPKVDWLFNGEVIRTNDHYVIETHA----LRIKNVK 202 Query: 76 VHSDAGVYWCEAT-NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRG 134 SD G+Y C A+ G + R + V E + +G++ + C G Sbjct: 203 -ESDDGIYTCRASVEQTGELQERAIRVEVHTRPSIVEAENSVYEVTEGESAQILC-KGTG 260 Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193 P P W K R + D G L I + ++ D+G YQC A NAAG I Sbjct: 261 KPPPKFTWIKTLTKENLAVTDRFSVNEDTGLLTISNVKRDDSGEYQCTATNAAGMAIMNI 320 Query: 194 ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG------GGNMPLG 247 + + +KP ++ +AQ G C+ G P P + +R+ G Sbjct: 321 -QVNVIVKPKIMEFLNQTIAQ-GEKTVLSCKAFGKPPPTITFRKHTSEKPFIRGVQPEDD 378 Query: 248 RVKVLDD---------GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-NL 297 R+ + +D G+L +D+ + +D+G Y C A N G +G+LTV PPS ++ Sbjct: 379 RIHLTNDFDDQQGETVGNLTIDHTLRSDDGLYECIANNKGGMAFKNGHLTVEFPPSFASM 438 Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGN 331 S ++ TC A P T+ W+ GN Sbjct: 439 SNRTIYSWDNRPVNLTCIAESIPNATIHWTYYGN 472 Score = 75.8 bits (178), Expect = 7e-12 Identities = 88/354 (24%), Positives = 150/354 (42%), Gaps = 37/354 (10%) Query: 155 SRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVA 213 + +H D +L ++ AG+Y C A S ++ + P + Sbjct: 95 TELHPQDNSISLFFNSLQEDQAGQYICRGTYANTELLSKTVIIETIVAITWDDAPLNQFP 154 Query: 214 QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCE 273 G +C+V P P V W + G + V++ +LR+ NV +D+G Y+C Sbjct: 155 ILGEDFAIKCQVRARPSPKVDWLFN--GEVIRTNDHYVIETHALRIKNVKESDDGIYTCR 212 Query: 274 AE-NSVGAVSASGY-LTVYDPPSINLSPNSV-NVESGNVARFTCTATGRPEPTMFWSVEG 330 A G + + V+ PSI + NSV V G A+ C TG+P P W Sbjct: 213 ASVEQTGELQERAIRVEVHTRPSIVEAENSVYEVTEGESAQILCKGTGKPPPKFTWI--- 269 Query: 331 NRTIIFPGMS-RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389 +T+ ++ D++ +V + +LTI++ ++DS C+A N AG + + ++ V Sbjct: 270 -KTLTKENLAVTDRF---SVNEDTGLLTISNVKRDDS-GEYQCTATNAAGMAIMNIQVNV 324 Query: 390 TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW--YFEGEALI-----QNH 442 P I+ NQT+ V C A P P I + + + I ++ Sbjct: 325 IVK----PKIMEF--LNQTIAQGEKTVLSCKAFGKPPPTITFRKHTSEKPFIRGVQPEDD 378 Query: 443 RRNVTND---------GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 R ++TND G L + +SD G Y C+A+++ G +G L V+ P Sbjct: 379 RIHLTNDFDDQQGETVGNLTIDHTLRSDDGLYECIANNKGGMAFKNGHLTVEFP 432 Score = 42.3 bits (95), Expect = 0.078 Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 1/91 (1%) Query: 402 NGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSD 461 + P NQ + C P P + W F GE +I+ + V L +K++ +SD Sbjct: 147 DAPLNQFPILGEDFAIKCQVRARPSPKVDWLFNGE-VIRTNDHYVIETHALRIKNVKESD 205 Query: 462 SGTYTCVASSRHGKYVWSGALLVDSPINPNI 492 G YTC AS + A+ V+ P+I Sbjct: 206 DGIYTCRASVEQTGELQERAIRVEVHTRPSI 236 >UniRef50_UPI00015B50B3 Cluster: PREDICTED: similar to cell adhesion molecule; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to cell adhesion molecule - Nasonia vitripennis Length = 977 Score = 109 bits (262), Expect = 5e-22 Identities = 83/281 (29%), Positives = 130/281 (46%), Gaps = 25/281 (8%) Query: 30 TLNCRAGGSPSPAIRWYKGGV---LVVSD-----THRSILPAGGLFFLRATHGRVHSDAG 81 TL+C A G P+P W+K +VS +H +GG + + + D G Sbjct: 260 TLSCLADGYPTPTYEWFKEDFENDRLVSKKIDPLSHNRYTISGGTLIIFSPNQT--EDRG 317 Query: 82 VYWCEATNSYGTARSRNATLHVAVLREEFR---LEPESKQSAQGDTVVLECLPPRGSPEP 138 Y C+ATN +GT RS + + A L+ F+ LEPE+ +A+G V L C P +P P Sbjct: 318 TYHCKATNKFGTIRSESVDIFAA-LKPSFKKRPLEPET-YAAEGGNVTLIC-NPEAAPRP 374 Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198 WKK+G L G R + D G+L+I + D G Y C N G ES + + Sbjct: 375 KFTWKKDGNVLGSGG--RRRITDTGSLIISPVSRDDEGTYVCQVSNEYGNDESRGRLIVL 432 Query: 199 HIKPYLITG-PEDVVAQTGSSVTFQCRVGGDPLPDV--LWRRS---AGGGNMPLGRVKVL 252 + P LI P + + T +C D + DV +W + ++ V+ Sbjct: 433 N-GPVLIESLPPTIRTAVNLNQTLRCMAYTDEMLDVAYIWMHNDMRIRDKDLKANPHIVI 491 Query: 253 DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293 + G L + N A+ G+Y C +++VG +S+ +T+ PP Sbjct: 492 NGGQLDIINATFAEAGDYECIVKSTVGRISSRTTITIEGPP 532 Score = 71.3 bits (167), Expect = 1e-10 Identities = 61/199 (30%), Positives = 81/199 (40%), Gaps = 17/199 (8%) Query: 110 FRLEPESK-----QSAQGDTVVLECLPPRGSPEPNVYWKK----NGQTLLFDGDSRMH-- 158 F +PE+K + + V L CL G P P W K N + + D H Sbjct: 239 FTKQPENKVFDVTKRVVNNDVTLSCLAD-GYPTPTYEWFKEDFENDRLVSKKIDPLSHNR 297 Query: 159 -LVDGGNLVIQDARQT-DAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP--EDVVAQ 214 + GG L+I QT D G Y C A N GT S + +KP P + A Sbjct: 298 YTISGGTLIIFSPNQTEDRGTYHCKATNKFGTIRSESVDIFAALKPSFKKRPLEPETYAA 357 Query: 215 TGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEA 274 G +VT C P P W++ G GR ++ D GSL + V DEG Y C+ Sbjct: 358 EGGNVTLICNPEAAPRPKFTWKKD-GNVLGSGGRRRITDTGSLIISPVSRDDEGTYVCQV 416 Query: 275 ENSVGAVSASGYLTVYDPP 293 N G + G L V + P Sbjct: 417 SNEYGNDESRGRLIVLNGP 435 Score = 65.7 bits (153), Expect = 7e-09 Identities = 131/578 (22%), Positives = 213/578 (36%), Gaps = 74/578 (12%) Query: 266 DEGEYSCEAENSVGAV-SASGYLTVYDPPSIN---LSPNSVNVESGNVARFTCTATGRPE 321 D G Y C+A N G + S S + PS L P + E GNV C P Sbjct: 315 DRGTYHCKATNKFGTIRSESVDIFAALKPSFKKRPLEPETYAAEGGNVT-LICNPEAAPR 373 Query: 322 PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381 P W +GN + R + T L I+ ++D T VC N G+ Sbjct: 374 PKFTWKKDGN---VLGSGGRRRITDTGS------LIISPVSRDDE-GTYVCQVSNEYGND 423 Query: 382 FVRGKLTVTSD----DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437 RG+L V + + PP I T NQTL + MA T I + + Sbjct: 424 ESRGRLIVLNGPVLIESLPPTIRTAVNLNQTL--RCMAY---TDEMLDVAYIWMHNDMRI 478 Query: 438 LIQNHRRN---VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHF 494 ++ + N V N G L + + +++G Y C+ S G+ + ++ P Sbjct: 479 RDKDLKANPHIVINGGQLDIINATFAEAGDYECIVKSTVGRISSRTTITIEGP------- 531 Query: 495 FRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTP 554 PGPP NV TSV LSW+ + I Y + + + N Sbjct: 532 ---------PGPPGGIQVLNVVKTSVDLSWT-DGAYNGRPIDRYTISAKTNWNQTWFNLT 581 Query: 555 RNSRGWVVIARRVHQTHYVVKSLI-PGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNS 613 + + + R + +++++ P TY F ++ N G PS S + D Sbjct: 582 EDFTAYTIGDRNTGRKRAHLENVLRPFTTYEFRIQAGNELGYGPPSLPSPQYSTPSDK-- 639 Query: 614 LWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEIL--NFYYLEGLF--IYFR 669 + + R + TIK W+ L + Y G+F +Y+R Sbjct: 640 -----PIVAPSNIRGG-----------GGKLGDLTIK--WDPLKSSEQYGPGIFYKVYWR 681 Query: 670 PLDNITIEYEMKTILHSN-DVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLD 728 + + H N +S I S YT+YE + G S + + Sbjct: 682 RKKGESEFQSLALKEHGNVGMSVVPIQSQYYYTEYEVMVQAANDVGYGPKSEIFTIYSAE 741 Query: 729 DVPDGPPINIEMFILNTTTVHLKWSPPELQLQ--NGIITGYNVVVNWLDVPANKSMVAIN 786 D+P P + F N T +++ W+P E + G + G+ + W + + V Sbjct: 742 DMPQVAPQLVTAFSYNGTALNVTWNPIEQTRERVRGRLIGHRIKY-WKENGREEDAVYYL 800 Query: 787 TTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQK 824 + + SL++ L Y V++ A G GP S++ Sbjct: 801 SRTTRPWSLVV-GLQPDTYYYVKVMAYNSAGEGPESER 837 Score = 57.2 bits (132), Expect = 3e-06 Identities = 46/179 (25%), Positives = 67/179 (37%), Gaps = 6/179 (3%) Query: 308 NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY-HATAVFDGVTVLTINDTDKNDS 366 N +C A G P PT W E D H G T++ + D Sbjct: 257 NDVTLSCLADGYPTPTYEWFKEDFENDRLVSKKIDPLSHNRYTISGGTLIIFSPNQTED- 315 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTP 425 R T C A N G+ +R + +V P +T + V C P Sbjct: 316 RGTYHCKATNKFGT--IRSE-SVDIFAALKPSFKKRPLEPETYAAEGGNVTLICNPEAAP 372 Query: 426 EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 P W +G L RR +T+ G+L++ + + D GTY C S+ +G G L+V Sbjct: 373 RPKFTWKKDGNVLGSGGRRRITDTGSLIISPVSRDDEGTYVCQVSNEYGNDESRGRLIV 431 Score = 35.9 bits (79), Expect = 6.7 Identities = 42/170 (24%), Positives = 76/170 (44%), Gaps = 8/170 (4%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753 + L+ T Y ++ + EG S + +T P PP ++ +F N T+V + W Sbjct: 810 VVGLQPDTYYYVKVMAYNSAGEGPESERYLQRTFRRAPQKPPSSVNVFGRNPTSVRVTWR 869 Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTV-HQATSLIMTNLTSGVSYSVQIAA 812 + + G+ + V W + + S A++T V A I+ NL G Y +++ A Sbjct: 870 YVQNPNGEEPVIGFKIRV-W-ETDQDMS-TAVDTLVPPDAIVAIIENLGVGKEYFLRMLA 926 Query: 813 ETIIGLGPFSQKVY-FNI-DSRSVGLDLLSRYPMNGEVSIVAGDFVMETW 860 + G G S + F + D+ G D SR ++ + IV+ F ++ W Sbjct: 927 YSNGGDGRMSSPAHRFRMGDATDYGND-ASRRKLDSMLLIVSILF-LKVW 974 >UniRef50_A7SVH6 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 336 Score = 109 bits (262), Expect = 5e-22 Identities = 100/357 (28%), Positives = 151/357 (42%), Gaps = 40/357 (11%) Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181 G +VL+C P G P P+ W NG+ L G + + G LVI D+G+YQC Sbjct: 3 GAKLVLQC-PSTGVPLPSTSWSLNGEPLEKGGRADLR---GTELVIPAVAGVDSGKYQCT 58 Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS--- 238 A N A +LK P ++T + V TG+ V+ C V G P P V W ++ Sbjct: 59 ASNVIALDSRASDSLKSR-DPVIVTIGDKVETLTGTEVSIICPVEGLPPPKVTWAKNGPI 117 Query: 239 AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298 A G + R L S + + D G YSC A N++G +A V ++ + Sbjct: 118 ASGDKFTIARSTDLVFNSGKAS---VFDSGRYSCRAVNNLGQDTAYSEFIVNATFTVTIG 174 Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358 N V+ G+ TCTA G P P + W +G T+ G T+ Sbjct: 175 AN-VSALRGSSITLTCTAEGLPVPAVVWK-KGGATLQ---------------QGGRAFTL 217 Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418 + T+ DS C A N G++ +T+ P G + ++ Sbjct: 218 SSTESADS-GRYDCVATNLKGTAMASSAVTIHGTLGDPHLGRKVGGTRTSIS-------- 268 Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHG 474 C A P P+I W GE+++ + DG+ L+L + K D+G Y C+AS+ G Sbjct: 269 CPATGFPNPLIRWSRNGESVVPGGHLKI--DGSKLLLTNPQKEDNGVYKCLASNPGG 323 Score = 89.4 bits (212), Expect = 5e-16 Identities = 82/306 (26%), Positives = 124/306 (40%), Gaps = 26/306 (8%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 L C + G P P+ W G + + G + A G D+G Y C A+N Sbjct: 8 LQCPSTGVPLPSTSWSLNGEPLEKGGRADL--RGTELVIPAVAG---VDSGKYQCTASNV 62 Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150 + +L R+ + K T V P G P P V W KNG + Sbjct: 63 IALDSRASDSLKS---RDPVIVTIGDKVETLTGTEVSIICPVEGLPPPKVTWAKNGP--I 117 Query: 151 FDGDSRMHLVDGGNLVIQDARQT--DAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208 GD + + +LV + + D+GRY C A N G +++A + ++ + +T Sbjct: 118 ASGD-KFTIARSTDLVFNSGKASVFDSGRYSCRAVNNLG-QDTAYSEFIVNAT-FTVTIG 174 Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268 +V A GSS+T C G P+P V+W++ GG + G + L + AD G Sbjct: 175 ANVSALRGSSITLTCTAEGLPVPAVVWKK--GGATLQQG------GRAFTLSSTESADSG 226 Query: 269 EYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328 Y C A N G AS +T++ P+ G +C ATG P P + WS Sbjct: 227 RYDCVATNLKGTAMASSAVTIHGTLG---DPHLGRKVGGTRTSISCPATGFPNPLIRWSR 283 Query: 329 EGNRTI 334 G + Sbjct: 284 NGESVV 289 Score = 81.4 bits (192), Expect = 1e-13 Identities = 75/259 (28%), Positives = 109/259 (42%), Gaps = 28/259 (10%) Query: 33 CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS-DAGVYWCEATNSY 91 C G P P + W K G + D +I + L F G+ D+G Y C A N+ Sbjct: 99 CPVEGLPPPKVTWAKNGPIASGDKF-TIARSTDLVF---NSGKASVFDSGRYSCRAVNNL 154 Query: 92 GTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150 G ++ ++ F + + SA +G ++ L C G P P V WKK G TL Sbjct: 155 G----QDTAYSEFIVNATFTVTIGANVSALRGSSITLTCTA-EGLPVPAVVWKKGGATLQ 209 Query: 151 FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED 210 G + + D+GRY C+A N GT A+A+ + I L G Sbjct: 210 QGGRA---------FTLSSTESADSGRYDCVATNLKGT---AMASSAVTIHGTL--GDPH 255 Query: 211 VVAQTGSSVT-FQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGE 269 + + G + T C G P P + W R+ G +P G +K+ D L L N D G Sbjct: 256 LGRKVGGTRTSISCPATGFPNPLIRWSRN-GESVVPGGHLKI-DGSKLLLTNPQKEDNGV 313 Query: 270 YSCEAENSVGAVSASGYLT 288 Y C A N G +A+ +T Sbjct: 314 YKCLASNPGGDATATSNMT 332 Score = 76.6 bits (180), Expect = 4e-12 Identities = 53/178 (29%), Positives = 85/178 (47%), Gaps = 22/178 (12%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 A + + +V+ R TL C A G P PA+ W KGG ++ G F L Sbjct: 167 ATFTVTIGANVSALRGSSITLTCTAEGLPVPAVVWKKGGA--------TLQQGGRAFTLS 218 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNA-TLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 +T +D+G Y C ATN GTA + +A T+H + +P + G + C Sbjct: 219 STES---ADSGRYDCVATNLKGTAMASSAVTIHGTL------GDPHLGRKVGGTRTSISC 269 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 P G P P + W +NG++++ G + +DG L++ + ++ D G Y+C+A N G Sbjct: 270 -PATGFPNPLIRWSRNGESVVPGGHLK---IDGSKLLLTNPQKEDNGVYKCLASNPGG 323 Score = 68.1 bits (159), Expect = 1e-09 Identities = 73/270 (27%), Positives = 100/270 (37%), Gaps = 26/270 (9%) Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAE 275 G+ + QC G PLP W S G + G L L + V D G+Y C A Sbjct: 3 GAKLVLQCPSTGVPLPSTSW--SLNGEPLEKGGRADLRGTELVIPAVAGVDSGKYQCTAS 60 Query: 276 NSVGAVS-ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334 N + S AS L DP + + + V +G C G P P + W+ G Sbjct: 61 NVIALDSRASDSLKSRDPVIVTIG-DKVETLTGTEVSIICPVEGLPPPKVTWAKNG---- 115 Query: 335 IFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394 P S DK+ D V DS C AVN G + V + Sbjct: 116 --PIASGDKFTIARSTD--LVFNSGKASVFDS-GRYSCRAVNNLGQDTAYSEFIVNATF- 169 Query: 395 RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVL 454 +T G + L S+ + CTA P P + W G L Q R L Sbjct: 170 ----TVTIGANVSALRGSSITL-TCTAEGLPVPAVVWKKGGATLQQGGR-------AFTL 217 Query: 455 KDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 + +DSG Y CVA++ G + S A+ + Sbjct: 218 SSTESADSGRYDCVATNLKGTAMASSAVTI 247 >UniRef50_A7SSL0 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 270 Score = 109 bits (262), Expect = 5e-22 Identities = 83/285 (29%), Positives = 127/285 (44%), Gaps = 26/285 (9%) Query: 30 TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89 TL C A G P P I+WYKG LVV D R + G + A SD G Y C A N Sbjct: 12 TLECLATGYPPPKIQWYKGRELVVPD-RRIATSSRGHLVINAIQ---QSDTGYYTCVAVN 67 Query: 90 SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149 TA S + ++ +V + + + P+ D ++CL G P P V W K+ + L Sbjct: 68 ---TAGSDSVSVSFSVDQTDVFVFPD-------DNSAVQCLGV-GIPPPVVTWYKDDKPL 116 Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209 G R++ G L+I A D+G Y C+AR++AG+ +A+ + + + P ++ P Sbjct: 117 GVGG--RVYSTTQGELIISRATPEDSGTYSCVARSSAGS-VTAVVQVSVGVPPAILKRPS 173 Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGE 269 D+ G + +C G P P V W+ + G N+ +++ + + D G Sbjct: 174 DIAVNMGDVIRLECVFQGVPTPRVTWQHN--GRNLQYMTPRLV------IRDARPQDAGL 225 Query: 270 YSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314 Y C N G SA +TV P I P + G +C Sbjct: 226 YRCTGTNLAGRASAETSVTVRITPKIIQPPTDRTLNEGETLILSC 270 Score = 98.3 bits (234), Expect = 1e-18 Identities = 72/212 (33%), Positives = 102/212 (48%), Gaps = 19/212 (8%) Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181 GD++ LECL G P P + W K G+ L+ D R+ G+LVI +Q+D G Y C+ Sbjct: 8 GDSITLECLAT-GYPPPKIQWYK-GRELVVP-DRRIATSSRGHLVINAIQQSDTGYYTCV 64 Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241 A N AG+ +S + + + P+D S+V QC G P P V W + Sbjct: 65 AVNTAGS-DSVSVSFSVDQTDVFVF-PDD-----NSAV--QCLGVGIPPPVVTWYKD--- 112 Query: 242 GNMPLG---RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298 + PLG RV G L + D G YSC A +S G+V+A ++V PP+I Sbjct: 113 -DKPLGVGGRVYSTTQGELIISRATPEDSGTYSCVARSSAGSVTAVVQVSVGVPPAILKR 171 Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330 P+ + V G+V R C G P P + W G Sbjct: 172 PSDIAVNMGDVIRLECVFQGVPTPRVTWQHNG 203 Score = 78.6 bits (185), Expect = 1e-12 Identities = 64/205 (31%), Positives = 87/205 (42%), Gaps = 19/205 (9%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 DV V + + C G P P + WYK + G L RAT D Sbjct: 84 DVFVFPDDNSAVQCLGVGIPPPVVTWYKDDKPLGVGGRVYSTTQGELIISRAT----PED 139 Query: 80 AGVYWCEATNSYGTARSRNATLHVAV-LREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138 +G Y C A +S G S A + V+V + P GD + LEC+ +G P P Sbjct: 140 SGTYSCVARSSAG---SVTAVVQVSVGVPPAILKRPSDIAVNMGDVIRLECV-FQGVPTP 195 Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198 V W+ NG+ L + LVI+DAR DAG Y+C N AG R SA ++ + Sbjct: 196 RVTWQHNGRNLQYMTP---------RLVIRDARPQDAGLYRCTGTNLAG-RASAETSVTV 245 Query: 199 HIKPYLITGPEDVVAQTGSSVTFQC 223 I P +I P D G ++ C Sbjct: 246 RITPKIIQPPTDRTLNEGETLILSC 270 Score = 56.8 bits (131), Expect = 3e-06 Identities = 65/267 (24%), Positives = 103/267 (38%), Gaps = 31/267 (11%) Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268 +D A+ G S+T +C G P P + W + +P R+ G L ++ + +D G Sbjct: 1 KDRSARIGDSITLECLATGYPPPKIQWYKGR-ELVVPDRRIATSSRGHLVINAIQQSDTG 59 Query: 269 EYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328 Y+C A N+ G+ S S S ++ V V + + C G P P + W Sbjct: 60 YYTCVAVNTAGSDSVS--------VSFSVDQTDVFVFPDDNSAVQCLGVGIPPPVVTWYK 111 Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT 388 + G+ Y T L I+ DS T C A + AGS +++ Sbjct: 112 DDKPL----GVGGRVYSTTQ-----GELIISRATPEDS-GTYSCVARSSAGSVTAVVQVS 161 Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN 448 V PP I PS+ + + + C P P + W G L R Sbjct: 162 V-----GVPPAILKRPSDIAVNMGDVIRLECVFQGVPTPRVTWQHNGRNLQYMTPR---- 212 Query: 449 DGTLVLKDLDKSDSGTYTCVASSRHGK 475 LV++D D+G Y C ++ G+ Sbjct: 213 ---LVIRDARPQDAGLYRCTGTNLAGR 236 Score = 44.8 bits (101), Expect = 0.015 Identities = 24/67 (35%), Positives = 35/67 (52%) Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVW 478 C A P P I WY E ++ + R ++ G LV+ + +SD+G YTCVA + G Sbjct: 15 CLATGYPPPKIQWYKGRELVVPDRRIATSSRGHLVINAIQQSDTGYYTCVAVNTAGSDSV 74 Query: 479 SGALLVD 485 S + VD Sbjct: 75 SVSFSVD 81 >UniRef50_UPI0000E4617C Cluster: PREDICTED: similar to novel immunoglobulin domain containing protein; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to novel immunoglobulin domain containing protein - Strongylocentrotus purpuratus Length = 2128 Score = 109 bits (261), Expect = 6e-22 Identities = 91/339 (26%), Positives = 135/339 (39%), Gaps = 17/339 (5%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 V G +I P V + A+L C+ G P P I+WY+ G L+ S++ R L Sbjct: 135 VILGPPKFISTPPDHVVFQENAEASLQCQGSGVPFPTIKWYRQGELITSNS-RITLSGDT 193 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 + R G D G Y C A NS G+ N T V + P+ G + Sbjct: 194 ITIKRVVRG----DVGTYSCVAENSEGSV--INDTRFVVEGPPYIFVPPQDTSVTLGQSA 247 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLL-FDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIA 182 L C W G + + R V G L+I+ + D G Y C Sbjct: 248 TLSCEALSSPDNLTQQWFYEGLLVQNVEQLQRRVTVSAPLGELLIRGTERGDRGTYSCTP 307 Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP-LPDVLWRRSAGG 241 N GT +A A L + +++ P +V A G C +P L +WR+ Sbjct: 308 TNGLGTPPTASAFLDVQYAAQVVSMPTEVYATRGEDAIIPCNTSANPALLYAIWRKDEAE 367 Query: 242 GNM-PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV--SASGYLTVYDPPSINLS 298 + R + ++GSL L L D+G Y+C N +G S L V DPP ++ Sbjct: 368 LRITQTNRYSITEEGSLVLGVATLNDQGSYTCTPYNDLGTAGQSTPTRLIVIDPPEFSIQ 427 Query: 299 PNSVNVES-GNVARFTCTAT-GRPEPTMFW-SVEGNRTI 334 P + +S + CTAT + T+ W V G+ +I Sbjct: 428 PEPMYEKSVDDSVSMPCTATESAVDTTLTWRKVNGDLSI 466 Score = 103 bits (247), Expect = 3e-20 Identities = 117/460 (25%), Positives = 193/460 (41%), Gaps = 55/460 (11%) Query: 118 QSAQGDTVVLECLPPRGSPEPN-------VYWKKNGQT----LLFDGDS---------RM 157 ++ GDTV+L C +P P+ + W++ + +LFD R+ Sbjct: 32 EARDGDTVILPCDRVLPTPPPDFPVALFILQWQRQDISQPFFVLFDSSDAIISPAFQGRV 91 Query: 158 HLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATLK--IHIKP--YLITGPEDVV 212 VD G +L + DAG Y+C + T + + P ++ T P+ VV Sbjct: 92 SQVDSGASLAMTGVTVDDAGIYECQIIELSDLESIGNGTFVNLVILGPPKFISTPPDHVV 151 Query: 213 AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV-LDDGSLRLDNVILADEGEYS 271 Q + + QC+ G P P + W R G + ++ L ++ + V+ D G YS Sbjct: 152 FQENAEASLQCQGSGVPFPTIKWYRQ---GELITSNSRITLSGDTITIKRVVRGDVGTYS 208 Query: 272 CEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEP-TMFWSVEG 330 C AENS G+V V PP I + P +V G A +C A P+ T W EG Sbjct: 209 CVAENSEGSVINDTRFVVEGPPYIFVPPQDTSVTLGQSATLSCEALSSPDNLTQQWFYEG 268 Query: 331 NRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT 390 ++ + + + T V + L I T++ D R T C+ N G+ Sbjct: 269 ---LLVQNVEQLQRRVT-VSAPLGELLIRGTERGD-RGTYSCTPTNGLGTPPTASAFL-- 321 Query: 391 SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA---LIQNHRRNVT 447 D + + + P+ A+ PC P + A + + EA + Q +R ++T Sbjct: 322 --DVQYAAQVVSMPTEVYATRGEDAIIPCNTSANPALLYAIWRKDEAELRITQTNRYSIT 379 Query: 448 NDGTLVLKDLDKSDSGTYTCVASS---RHGKYVWSGALLVDSP---INPNIHFFRAADVS 501 +G+LVL +D G+YTC + G+ + +++D P I P + ++ D Sbjct: 380 EEGSLVLGVATLNDQGSYTCTPYNDLGTAGQSTPTRLIVIDPPEFSIQPEPMYEKSVD-D 438 Query: 502 SLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541 S+ P T T + DT TL+W + N G SI + E Sbjct: 439 SVSMPCT--ATESAVDT--TLTWRKVN--GDLSIRAFITE 472 Score = 81.4 bits (192), Expect = 1e-13 Identities = 107/437 (24%), Positives = 172/437 (39%), Gaps = 40/437 (9%) Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNAT-LHVAVLREE--FRLEPESKQSAQGDTVVL 127 A G DAG+Y C+ N T +++ +L P+ + L Sbjct: 101 AMTGVTVDDAGIYECQIIELSDLESIGNGTFVNLVILGPPKFISTPPDHVVFQENAEASL 160 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 +C G P P + W + G+ L +SR+ L G + I+ + D G Y C+A N+ G Sbjct: 161 QC-QGSGVPFPTIKWYRQGE--LITSNSRITL-SGDTITIKRVVRGDVGTYSCVAENSEG 216 Query: 188 TRESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 S I + ++ PY+ P+D G S T C P D L ++ G + Sbjct: 217 ---SVINDTRFVVEGPPYIFVPPQDTSVTLGQSATLSCEALSSP--DNLTQQWFYEGLLV 271 Query: 246 LG------RVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAV-SASGYLTVYDPPSINL 297 RV V G L + D G YSC N +G +AS +L V + Sbjct: 272 QNVEQLQRRVTVSAPLGELLIRGTERGDRGTYSCTPTNGLGTPPTASAFLDVQYAAQVVS 331 Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 P V G A C + P + +++ ++Y T +G VL Sbjct: 332 MPTEVYATRGEDAIIPCNTSANP--ALLYAIWRKDEAELRITQTNRYSITE--EGSLVLG 387 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ-TLPIKSMAV 416 + ND + + C+ N G++ G+ T T PP + P + Sbjct: 388 V--ATLND-QGSYTCTPYNDLGTA---GQSTPTRLIVIDPPEFSIQPEPMYEKSVDDSVS 441 Query: 417 FPCTAI-CTPEPIIAWY-FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 PCTA + + W G+ I R +T +G ++K + K D GTY C+A+++ Sbjct: 442 MPCTATESAVDTTLTWRKVNGDLSI---RAFITENGLDIMK-ISKEDHGTYECMATNQVA 497 Query: 475 KYVWSGALLVDSPINPN 491 + S L+V SP +P+ Sbjct: 498 TVIASADLIV-SPTSPH 513 Score = 64.5 bits (150), Expect = 2e-08 Identities = 58/216 (26%), Positives = 91/216 (42%), Gaps = 18/216 (8%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIR-WYKGGV-LVVSDTHR-SILPAGGLF 67 A ++ P +V R + A + C +P+ W K L ++ T+R SI G L Sbjct: 326 AAQVVSMPTEVYATRGEDAIIPCNTSANPALLYAIWRKDEAELRITQTNRYSITEEGSLV 385 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK-QSAQGDTVV 126 AT +D G Y C N GTA T + + EF ++PE + + D+V Sbjct: 386 LGVATL----NDQGSYTCTPYNDLGTAGQSTPTRLIVIDPPEFSIQPEPMYEKSVDDSVS 441 Query: 127 LECLPPRGSPEPNVYWKK-NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 + C + + + W+K NG D R + + G L I + D G Y+C+A N Sbjct: 442 MPCTATESAVDTTLTWRKVNG-----DLSIRAFITENG-LDIMKISKEDHGTYECMATNQ 495 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTF 221 T IA+ + + P P DV T S+ + Sbjct: 496 VAT---VIASADLIVSPTSPHTPTDVAVVTSSTSAY 528 >UniRef50_UPI0000DB6E73 Cluster: PREDICTED: similar to CG31190-PB, isoform B, partial; n=2; Apocrita|Rep: PREDICTED: similar to CG31190-PB, isoform B, partial - Apis mellifera Length = 1985 Score = 109 bits (261), Expect = 6e-22 Identities = 95/351 (27%), Positives = 145/351 (41%), Gaps = 26/351 (7%) Query: 4 DYVTSGEAP-YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG----GVLVVSDTHR 58 + V + P +++E P + + + L+C A GSP+P + W V V R Sbjct: 4 ELVVGQQGPVFVLEPPSTLVFSNTTGSQLSCSAHGSPTPHVTWITSPDQRSVTAVPGL-R 62 Query: 59 SILPAGGLFF--LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPES 116 +L G L+F A R Y C AT+S GT SR TL + + + Sbjct: 63 QLLGNGTLYFPPFLAQDFRAEVHNARYRCRATSSVGTVLSREVTLRAVLTVPGYDVRVNR 122 Query: 117 KQSAQGDTVVLECLPPRGSPEPNVY--WKKNGQTLL---FDGDSRMHLVDGGNLVIQDAR 171 +G VL C E W ++ LL D R + G+L I+ AR Sbjct: 123 SPVLEGCNAVLSCTAREDVKEHLTVTSWFRDDAILLPGSTDTGGRFVVTSQGDLHIRAAR 182 Query: 172 QTDA-GRYQCIARNA--AGTRESAIATLKIH-----IKPYLITGPEDVV-AQTGSSVTFQ 222 D Y C+ +A R S ATL + + P L+ + + A++GS V Sbjct: 183 PDDGRATYSCLTFHALTGERRRSEPATLTVTEPTGTMPPRLMQRSQIAISAESGSDVHLT 242 Query: 223 CRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279 C G+P P W R G ++P+ GR+++ D +++ V D G Y C A N VG Sbjct: 243 CSAQGNPAPQFAWYRDVNGHSIPVESFGRIQLWGD-LMQIRRVDAQDAGRYICRASNQVG 301 Query: 280 AVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330 A +L+V + + P + SG A CT G P ++ W +G Sbjct: 302 EQRAETHLSVTSKLNARIQPRVQIINSGESATMNCTVEGYPVESVEWLHDG 352 Score = 103 bits (247), Expect = 3e-20 Identities = 97/380 (25%), Positives = 151/380 (39%), Gaps = 24/380 (6%) Query: 30 TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89 T+ C G P ++ W +GGV + D + G L +DAG Y C Sbjct: 550 TIACPYSGYPITSVEWSRGGVALPLDIRHRVDSEGHLTIANVD----PNDAGTYTCMVRA 605 Query: 90 SYGTARSRNATLHVA--VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147 G SR+ L V+ + F P + Q +G + C G W K+G+ Sbjct: 606 RSGETASRDIRLTVSSPPIMTPFNF-PSNLQ--EGSRAQVTCTVTSGDLPIYFSWLKDGE 662 Query: 148 TLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT 206 L + + + LV ++ +G+Y C+A N+A + + A L + + P I Sbjct: 663 PLPSSLRIEERVAEFFSLLVFKELSSRHSGKYTCVATNSA-AKVNHTAELLVKVPPQWIF 721 Query: 207 GPEDVVAQTGSSVTFQCRVGGDPLPDVLW---RRSAGGGNMPL-----GRVKVLDDGSLR 258 P+DV G+ + C G P P V W R PL GR+ +L +GSL Sbjct: 722 EPQDVATLLGNPLNVHCEAKGFPPPRVTWLRARERTSNDYQPLIDGTDGRLTILPNGSLW 781 Query: 259 LDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317 + DEG Y C A N +G+ +S Y++V++P +V + G CT Sbjct: 782 TASAGPQDEGHYLCRANNGIGSGLSKVIYVSVHEPARFEFQSKNVTIRRGESVTLDCTVI 841 Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV-TVLTINDTDKNDSRNTIVCSAVN 376 G + W +R + R +G+ + L+I +D+ DS C+A N Sbjct: 842 GDNPIEVQWMHNSDR--LDTNNHRLSISQIKTDNGLKSQLSIGSSDRQDS-GVYRCTADN 898 Query: 377 YAGSSFVRGKLTVTSDDDRP 396 G S L V D P Sbjct: 899 AYGRSEHLIYLAVQERPDPP 918 Score = 83.0 bits (196), Expect = 4e-14 Identities = 105/412 (25%), Positives = 160/412 (38%), Gaps = 30/412 (7%) Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138 D G+Y C A N+ T + A L++ + P ++ G + C P G P Sbjct: 506 DGGLYACVAANTLATVEHK-ARLNIYGPPYIRSIGPV--RAIAGVDTTIAC-PYSGYPIT 561 Query: 139 NVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197 +V W + G L D H VD G+L I + DAG Y C+ R +G S L Sbjct: 562 SVEWSRGGVALPLD---IRHRVDSEGHLTIANVDPNDAGTYTCMVRARSGETASRDIRLT 618 Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RV--KVLDD 254 + P + Q GS C V LP + + G +P R+ +V + Sbjct: 619 VSSPPIMTPFNFPSNLQEGSRAQVTCTVTSGDLP-IYFSWLKDGEPLPSSLRIEERVAEF 677 Query: 255 GSLRLDNVILA-DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313 SL + + + G+Y+C A NS V+ + L V PP P V GN Sbjct: 678 FSLLVFKELSSRHSGKYTCVATNSAAKVNHTAELLVKVPPQWIFEPQDVATLLGNPLNVH 737 Query: 314 CTATGRPEPTMFWSVEGNRTI--IFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371 C A G P P + W RT P + T + +G ++ T + +++ + Sbjct: 738 CEAKGFPPPRVTWLRARERTSNDYQPLIDGTDGRLTILPNG-SLWTASAGPQDEGH--YL 794 Query: 372 CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431 C A N GS K+ S + P N T+ CT I + W Sbjct: 795 CRANNGIGSGL--SKVIYVSVHE--PARFEFQSKNVTIRRGESVTLDCTVIGDNPIEVQW 850 Query: 432 YFEGEAL-IQNHRRNV----TNDGT---LVLKDLDKSDSGTYTCVASSRHGK 475 + L NHR ++ T++G L + D+ DSG Y C A + +G+ Sbjct: 851 MHNSDRLDTNNHRLSISQIKTDNGLKSQLSIGSSDRQDSGVYRCTADNAYGR 902 Score = 82.2 bits (194), Expect = 8e-14 Identities = 110/472 (23%), Positives = 183/472 (38%), Gaps = 53/472 (11%) Query: 45 WYKGGVLVV---SDTH-RSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNAT 100 W++ +++ +DT R ++ + G +RA R Y C ++ R R+ Sbjct: 150 WFRDDAILLPGSTDTGGRFVVTSQGDLHIRAA--RPDDGRATYSCLTFHALTGERRRSEP 207 Query: 101 LHVAVLREEFRLEPESKQSAQ-------GDTVVLECLPPRGSPEPNVYWKK--NGQTLLF 151 + V + P Q +Q G V L C +G+P P W + NG ++ Sbjct: 208 ATLTVTEPTGTMPPRLMQRSQIAISAESGSDVHLTC-SAQGNPAPQFAWYRDVNGHSIPV 266 Query: 152 DGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDV 211 + R+ L G + I+ DAGRY C A N G + A L + K P Sbjct: 267 ESFGRIQLW-GDLMQIRRVDAQDAGRYICRASNQVG-EQRAETHLSVTSKLNARIQPRVQ 324 Query: 212 VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNVILADEGEY 270 + +G S T C V G P+ V W R+++L L + +V D+G Y Sbjct: 325 IINSGESATMNCTVEGYPVESVEWLHDGVPVLTAQDTRIRLLAPLVLVIGSVGRKDKGMY 384 Query: 271 SCEAENSVGAVSASGYLTVYDP-PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWS-- 327 C + A+ L + D P + + + G C+ATG P P+ W Sbjct: 385 QCLVRSDKENAQATAELKLGDTVPELQYTFIEQALRPGPPVSLRCSATGSPPPSFTWLLD 444 Query: 328 -------------VEGNRTIIFPGMSRDKY------HATAVF-----DGVTVLTINDTDK 363 V G+ +I P ++R +A + D ++ L I+ Sbjct: 445 GEPLSEIASGHRFVSGSPSINNPLLNRCTMAGWLYRYAIGQYVDQSGDVISHLNISSAGA 504 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423 D C A N + + +L + PP I + GP + + P + Sbjct: 505 EDG-GLYACVAANTLATVEHKARLNIYG----PPYIRSIGPVRAIAGVDTTIACPYSGY- 558 Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 P + W G AL + R V ++G L + ++D +D+GTYTC+ +R G+ Sbjct: 559 -PITSVEWSRGGVALPLDIRHRVDSEGHLTIANVDPNDAGTYTCMVRARSGE 609 Score = 78.2 bits (184), Expect = 1e-12 Identities = 98/378 (25%), Positives = 143/378 (37%), Gaps = 32/378 (8%) Query: 164 NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT-GPEDVVAQTGSSVTFQ 222 +L I A D G Y C+A N T E A L I+ PY+ + GP +A G T Sbjct: 496 HLNISSAGAEDGGLYACVAANTLATVEHK-ARLNIYGPPYIRSIGPVRAIA--GVDTTIA 552 Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281 C G P+ V W R GG +PL R +V +G L + NV D G Y+C G Sbjct: 553 CPYSGYPITSVEWSR--GGVALPLDIRHRVDSEGHLTIANVDPNDAGTYTCMVRARSGET 610 Query: 282 SASGY-LTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF-WSVEGNRTIIFPGM 339 ++ LTV PP + N++ G+ A+ TCT T P F W +G P Sbjct: 611 ASRDIRLTVSSPPIMTPFNFPSNLQEGSRAQVTCTVTSGDLPIYFSWLKDGEP---LPSS 667 Query: 340 SRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPI 399 R + F ++L + S C A N A +L V PP Sbjct: 668 LRIEERVAEFF---SLLVFKELSSRHS-GKYTCVATNSAAKVNHTAELLVKV----PPQW 719 Query: 400 ITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH---------RRNVTNDG 450 I TL + V C A P P + W E ++ R + +G Sbjct: 720 IFEPQDVATLLGNPLNVH-CEAKGFPPPRVTWLRARERTSNDYQPLIDGTDGRLTILPNG 778 Query: 451 TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKP 510 +L D G Y C A++ G + ++ S P F++ +V+ G Sbjct: 779 SLWTASAGPQDEGHYLCRANNGIGSGL--SKVIYVSVHEPARFEFQSKNVTIRRGESVTL 836 Query: 511 ITHNVTDTSVTLSWSQNN 528 + D + + W N+ Sbjct: 837 DCTVIGDNPIEVQWMHNS 854 Score = 77.4 bits (182), Expect = 2e-12 Identities = 67/245 (27%), Positives = 104/245 (42%), Gaps = 19/245 (7%) Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139 +G Y C ATNS + A L V V ++ EP+ + G+ + + C +G P P Sbjct: 691 SGKYTCVATNSAAKV-NHTAELLVKV-PPQWIFEPQDVATLLGNPLNVHC-EAKGFPPPR 747 Query: 140 VYWKK------NGQTLLFDG-DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192 V W + N L DG D R+ ++ G+L A D G Y C A N G+ S Sbjct: 748 VTWLRARERTSNDYQPLIDGTDGRLTILPNGSLWTASAGPQDEGHYLCRANNGIGSGLSK 807 Query: 193 IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW-----RRSAGGGNMPLG 247 + + +H ++V + G SVT C V GD +V W R + + Sbjct: 808 VIYVSVHEPARFEFQSKNVTIRRGESVTLDCTVIGDNPIEVQWMHNSDRLDTNNHRLSIS 867 Query: 248 RVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304 ++K D+G L + + D G Y C A+N+ G YL V + P S + + Sbjct: 868 QIKT-DNGLKSQLSIGSSDRQDSGVYRCTADNAYGRSEHLIYLAVQERPDPPASLEVIEI 926 Query: 305 ESGNV 309 S ++ Sbjct: 927 GSRSI 931 Score = 76.2 bits (179), Expect = 5e-12 Identities = 60/211 (28%), Positives = 96/211 (45%), Gaps = 16/211 (7%) Query: 31 LNCRAGGSPSPAIRWYK--GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88 L C A G+P+P WY+ G + ++ I G L +R + DAG Y C A+ Sbjct: 241 LTCSAQGNPAPQFAWYRDVNGHSIPVESFGRIQLWGDLMQIRRVDAQ---DAGRYICRAS 297 Query: 89 NSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147 N G R A H++V + R++P + G++ + C G P +V W +G Sbjct: 298 NQVGEQR---AETHLSVTSKLNARIQPRVQIINSGESATMNCTV-EGYPVESVEWLHDGV 353 Query: 148 TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI---KPYL 204 +L D+R+ L+ LVI + D G YQC+ R+ +E+A AT ++ + P L Sbjct: 354 PVLTAQDTRIRLLAPLVLVIGSVGRKDKGMYQCLVRS---DKENAQATAELKLGDTVPEL 410 Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235 + + G V+ +C G P P W Sbjct: 411 QYTFIEQALRPGPPVSLRCSATGSPPPSFTW 441 Score = 62.1 bits (144), Expect = 9e-08 Identities = 39/136 (28%), Positives = 65/136 (47%), Gaps = 4/136 (2%) Query: 693 EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKW 752 ++T LRK+TKY+ + F G S V T + VP+ PP + L++ +V + W Sbjct: 1110 QLTGLRKFTKYDISIRAFNSIASGPASVPIVGTTQEGVPETPPTQVTCVPLSSQSVKVSW 1169 Query: 753 SPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSL--IMTNLTSGVSYSVQI 810 S P GII GY V + VP + ++ V + +S+ + L +YS+++ Sbjct: 1170 SAPPPHQHGGIIQGYKVY--YRPVPTDNMDISTVREVKKTSSVETYLHTLYKYTNYSIRV 1227 Query: 811 AAETIIGLGPFSQKVY 826 A T G G S ++ Sbjct: 1228 LAYTGAGDGVLSPPIF 1243 Score = 58.0 bits (134), Expect = 1e-06 Identities = 58/200 (29%), Positives = 86/200 (43%), Gaps = 27/200 (13%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG---------GVLVVSDTHRSILP 62 P I +P DV P ++C A G P P + W + ++ +D +ILP Sbjct: 717 PQWIFEPQDVATLLGNPLNVHCEAKGFPPPRVTWLRARERTSNDYQPLIDGTDGRLTILP 776 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-- 120 G L+ T D G Y C A N G+ S+ ++V+V E R E +SK Sbjct: 777 NGSLW----TASAGPQDEGHYLCRANNGIGSGLSK--VIYVSV-HEPARFEFQSKNVTIR 829 Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL----VDGG---NLVIQDARQT 173 +G++V L+C +P V W N L + R+ + D G L I + + Sbjct: 830 RGESVTLDCTVIGDNP-IEVQWMHNSDR-LDTNNHRLSISQIKTDNGLKSQLSIGSSDRQ 887 Query: 174 DAGRYQCIARNAAGTRESAI 193 D+G Y+C A NA G E I Sbjct: 888 DSGVYRCTADNAYGRSEHLI 907 Score = 56.8 bits (131), Expect = 3e-06 Identities = 57/223 (25%), Positives = 90/223 (40%), Gaps = 30/223 (13%) Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470 IKS C + P P W + + +T DG L ++ L++S +G YTC AS Sbjct: 1367 IKSSITLSCLVVGNPTPRPIWTYRNSQISTGRHYELTADGHLNIRGLEQSVAGNYTCSAS 1426 Query: 471 SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530 + G + L+V P P P + + T+ S+ W+ N Sbjct: 1427 NLFGDDSITYTLVVVMP----------------PRAPILELQYTTTN-SIRFRWNHPNN- 1468 Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590 G ++I GY V S + R+ GW IA QT +++ L G +Y+ + Sbjct: 1469 GGATIQGY---VLSYK--------RDQGGWEEIALSPEQTEFILSGLKCGSSYLAHLTAH 1517 Query: 591 NSHGLSGPSPVSDSVTVGDDSNSLWEGTGVS-NSTEYRNNILT 632 N G PS + + T G E +S N T + N+L+ Sbjct: 1518 NRVGTGDPSSLISATTKGTAPLLPKERDIISANGTSVKLNLLS 1560 Score = 52.0 bits (119), Expect = 1e-04 Identities = 37/137 (27%), Positives = 69/137 (50%), Gaps = 11/137 (8%) Query: 639 IEATPIDSKTIKLMWEILNFYY----LEGLFIYFRPL--DNITIEYEMKTILHSNDVSGF 692 + P+ S+++K+ W + ++G +Y+RP+ DN+ I ++ + ++ V + Sbjct: 1155 VTCVPLSSQSVKVSWSAPPPHQHGGIIQGYKVYYRPVPTDNMDIS-TVREVKKTSSVETY 1213 Query: 693 EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKW 752 + +L KYT Y ++ + +G S T +DVP GPP I+ L ++ + W Sbjct: 1214 -LHTLYKYTNYSIRVLAYTGAGDGVLSPPIFCTTEEDVP-GPPAGIKALALTAESILVSW 1271 Query: 753 SPPELQLQNGIITGYNV 769 PP LQ NG ++ Y V Sbjct: 1272 LPP-LQ-PNGNVSKYTV 1286 Score = 50.8 bits (116), Expect = 2e-04 Identities = 72/308 (23%), Positives = 114/308 (37%), Gaps = 20/308 (6%) Query: 203 YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL--GRVKVLDDGSLRLD 260 +++ P +V + C G P P V W S ++ G ++L +G+L Sbjct: 14 FVLEPPSTLVFSNTTGSQLSCSAHGSPTPHVTWITSPDQRSVTAVPGLRQLLGNGTLYFP 73 Query: 261 NVILAD------EGEYSCEAENSVGAVSASGYL--TVYDPPSINLSPNSVNVESGNVARF 312 + D Y C A +SVG V + V P ++ N V G A Sbjct: 74 PFLAQDFRAEVHNARYRCRATSSVGTVLSREVTLRAVLTVPGYDVRVNRSPVLEGCNAVL 133 Query: 313 TCTATGR-PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371 +CTA E S + I+ PG + G L I +D R T Sbjct: 134 SCTAREDVKEHLTVTSWFRDDAILLPGSTDTGGRFVVTSQGD--LHIRAARPDDGRATYS 191 Query: 372 CSAVNYAGSSFVRGK---LTVTSDDDRPPP-IITNGPSNQTLPIKSMAVFPCTAICTPEP 427 C + R + LTVT PP ++ + S C+A P P Sbjct: 192 CLTFHALTGERRRSEPATLTVTEPTGTMPPRLMQRSQIAISAESGSDVHLTCSAQGNPAP 251 Query: 428 IIAWYFE--GEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 AWY + G ++ +++ R + ++ +D D+G Y C AS++ G+ L V Sbjct: 252 QFAWYRDVNGHSIPVESFGRIQLWGDLMQIRRVDAQDAGRYICRASNQVGEQRAETHLSV 311 Query: 485 DSPINPNI 492 S +N I Sbjct: 312 TSKLNARI 319 Score = 47.2 bits (107), Expect = 0.003 Identities = 32/109 (29%), Positives = 53/109 (48%), Gaps = 6/109 (5%) Query: 718 PSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVP 777 P++ VA+T ++ P PP NI++ + + W PP + NG + GY +V W + Sbjct: 1030 PTDPVVAKTQEEAPTEPPQNIKVQSAGPGELMVSWQPPPKESCNGDLLGY--IVTWSEHS 1087 Query: 778 ANKSMV--AINTTVH--QATSLIMTNLTSGVSYSVQIAAETIIGLGPFS 822 ++ S V + + TV+ T + +T L Y + I A I GP S Sbjct: 1088 SSTSGVNQSKSLTVNGWATTKVQLTGLRKFTKYDISIRAFNSIASGPAS 1136 Score = 43.2 bits (97), Expect = 0.044 Identities = 35/133 (26%), Positives = 54/133 (40%), Gaps = 4/133 (3%) Query: 17 QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV 76 QP + + AT+NC G P ++ W GV V++ I L + + GR Sbjct: 320 QPRVQIINSGESATMNCTVEGYPVESVEWLHDGVPVLTAQDTRIRLLAPLVLVIGSVGR- 378 Query: 77 HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136 D G+Y C + A++ A L + E + + G V L C GSP Sbjct: 379 -KDKGMYQCLVRSDKENAQA-TAELKLGDTVPELQYTFIEQALRPGPPVSLRC-SATGSP 435 Query: 137 EPNVYWKKNGQTL 149 P+ W +G+ L Sbjct: 436 PPSFTWLLDGEPL 448 Score = 40.3 bits (90), Expect = 0.31 Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 3/78 (3%) Query: 217 SSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR-VKVLDDGSLRLDNVILADEGEYSCEAE 275 SS+T C V G+P P +W + + GR ++ DG L + + + G Y+C A Sbjct: 1369 SSITLSCLVVGNPTPRPIW--TYRNSQISTGRHYELTADGHLNIRGLEQSVAGNYTCSAS 1426 Query: 276 NSVGAVSASGYLTVYDPP 293 N G S + L V PP Sbjct: 1427 NLFGDDSITYTLVVVMPP 1444 Score = 38.7 bits (86), Expect = 0.96 Identities = 36/132 (27%), Positives = 50/132 (37%), Gaps = 8/132 (6%) Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTVVLECLP 131 G V S +W AT G R R+ S+ + A ++ L CL Sbjct: 1318 GLVESQLYEFWVSATTGLGEGEPTTIVTQTTNTRAPARVASFSQLLRRAIKSSITLSCLV 1377 Query: 132 PRGSPEPNVYWK-KNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190 G+P P W +N Q L G+L I+ Q+ AG Y C A N G + Sbjct: 1378 V-GNPTPRPIWTYRNSQ---ISTGRHYELTADGHLNIRGLEQSVAGNYTCSASNLFGD-D 1432 Query: 191 SAIATLKIHIKP 202 S TL + + P Sbjct: 1433 SITYTLVVVMPP 1444 Score = 37.9 bits (84), Expect = 1.7 Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 4/92 (4%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR----SI 60 YV+ E Q +VT+ R + TL+C G ++W + ++ HR I Sbjct: 810 YVSVHEPARFEFQSKNVTIRRGESVTLDCTVIGDNPIEVQWMHNSDRLDTNNHRLSISQI 869 Query: 61 LPAGGLFFLRATHGRVHSDAGVYWCEATNSYG 92 GL + D+GVY C A N+YG Sbjct: 870 KTDNGLKSQLSIGSSDRQDSGVYRCTADNAYG 901 >UniRef50_Q4SW90 Cluster: Chromosome undetermined SCAF13667, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF13667, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1278 Score = 109 bits (261), Expect = 6e-22 Identities = 134/562 (23%), Positives = 219/562 (38%), Gaps = 58/562 (10%) Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEA 274 G + +C G P P + W R GG++P +VK + + +L + V D GEY C A Sbjct: 340 GQQLLLECIAAGVPTPTIKWYRK--GGDLPERKVKFENFNKTLLVVGVSEEDAGEYVCMA 397 Query: 275 ENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334 N G++ S + V P P ++ + R C A G P+P + W + G Sbjct: 398 INHQGSIRHSILVQVKAAPYWLDKPTNLVLAPNENGRLVCRANGNPKPNIQWLINGQPIE 457 Query: 335 IFP-GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393 P SRD T +F V + S C+A N G ++V Sbjct: 458 SSPQNPSRDVLGDTIIFRSVQM---------GSSAVYQCNASNQYGYLLSNAFVSVL--- 505 Query: 394 DRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDG 450 D PP ++ GP NQ + + + C +P P + W+ G+ + +V N+G Sbjct: 506 DMPPRML--GPKNQLIKVIENNHTFLDCPFFGSPLPDLRWFKNGQGSGVDGGHYSVHNNG 563 Query: 451 TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV--DSPINPNIHFFRAADVSSLPGPPT 508 TL +K D GTYTCVASS GK L V ++ +NP++ +A P PP Sbjct: 564 TLEIKRARSEDEGTYTCVASSLLGKAENQVRLEVKEEASLNPSV---SSALPPDRPDPPL 620 Query: 509 KPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVH 568 + + SV L+W N S + + V+ G W ++ Sbjct: 621 ELDLSDPAVRSVRLTWIPGND-NRSPVTHFLVQFEEDRWEPGR--------WRNLSSYPG 671 Query: 569 QTHYVVKSLIPGITYMFIVRTENSHGLSGPS-PVSDSVTVGDDSNSLWEGTGVSNSTEYR 627 + V+ L P + Y F V NS G S PS P T G + + G S + Sbjct: 672 HLNSVILQLAPFVNYQFRVIAINSVGQSEPSLPSPQYKTSGAAPDVIPRGLRGWGSMKGN 731 Query: 628 NNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSN 687 I + +++L N YY ++++ D + ++ T + + Sbjct: 732 MEITWEPLLDLER-------------NGANLYY----SVWWKRKDT-SEDWNNVTTVRTK 773 Query: 688 DVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTT 747 V + + Y Y+ + + G SN + + +D P P + + ++T Sbjct: 774 HV----VHNTETYVPYQIKIQAGNEFGSGPESNIIIGYSGEDTPTDAPTELRVSRVDTNR 829 Query: 748 VHLKWSPPELQLQNGIITGYNV 769 H+ W +L+ G Y V Sbjct: 830 AHIHWKSVDLKSVQGEFKEYRV 851 Score = 99 bits (238), Expect = 4e-19 Identities = 76/281 (27%), Positives = 119/281 (42%), Gaps = 10/281 (3%) Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82 V R Q L C A G P+P I+WY+ G D + G DAG Sbjct: 337 VLRGQQLLLECIAAGVPTPTIKWYRKG----GDLPERKVKFENFNKTLLVVGVSEEDAGE 392 Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSPEPNVY 141 Y C A N G+ R ++ V V + L+ P + A + L C G+P+PN+ Sbjct: 393 YVCMAINHQGSIRH---SILVQVKAAPYWLDKPTNLVLAPNENGRLVCRA-NGNPKPNIQ 448 Query: 142 WKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201 W NGQ + + V G ++ + + + YQC A N G S + + Sbjct: 449 WLINGQPIESSPQNPSRDVLGDTIIFRSVQMGSSAVYQCNASNQYGYLLSNAFVSVLDMP 508 Query: 202 PYLITGPEDVVAQTGSSVTF-QCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLD 260 P ++ ++ ++ TF C G PLPD+ W ++ G + G V ++G+L + Sbjct: 509 PRMLGPKNQLIKVIENNHTFLDCPFFGSPLPDLRWFKNGQGSGVDGGHYSVHNNGTLEIK 568 Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301 DEG Y+C A + +G L V + S+N S +S Sbjct: 569 RARSEDEGTYTCVASSLLGKAENQVRLEVKEEASLNPSVSS 609 Score = 81.4 bits (192), Expect = 1e-13 Identities = 59/188 (31%), Positives = 93/188 (49%), Gaps = 14/188 (7%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS---DTHRSILPAGGLF 67 APY +++P ++ +A ++ L CRA G+P P I+W G + S + R +L G Sbjct: 415 APYWLDKPTNLVLAPNENGRLVCRANGNPKPNIQWLINGQPIESSPQNPSRDVL--GDTI 472 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTV 125 R+ + VY C A+N YG S NA + V + L P+++ + + + Sbjct: 473 IFRSVQ---MGSSAVYQCNASNQYGYLLS-NAFVSVLDMPPRM-LGPKNQLIKVIENNHT 527 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 L+C P GSP P++ W KNGQ DG + + G L I+ AR D G Y C+A + Sbjct: 528 FLDC-PFFGSPLPDLRWFKNGQGSGVDG-GHYSVHNNGTLEIKRARSEDEGTYTCVASSL 585 Query: 186 AGTRESAI 193 G E+ + Sbjct: 586 LGKAENQV 593 Score = 70.1 bits (164), Expect = 3e-10 Identities = 126/523 (24%), Positives = 199/523 (38%), Gaps = 70/523 (13%) Query: 10 EAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGL 66 + P I++Q + D V + C A G+P P W + G + D + G Sbjct: 1 QPPTIVKQSVKDYIVDPRDNIIIECEAKGNPVPDFSWRRNGKFFNLGKDPRVATQKDSGT 60 Query: 67 FFLRATHGRVHSD-AGVYWCEATNSYGTARSRNATL---------------HVAVLRE-- 108 + G D G Y C A+N G A S L H +V+ + Sbjct: 61 LEINFRSGGKQEDYEGEYQCFASNELGVALSNKILLRVSSEDTLLNTCRFSHSSVVSDCF 120 Query: 109 -----EFRLEPESKQS----AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL 159 E L P+ +G +++L C PP G P P ++W + T + D R+ + Sbjct: 121 CATTLEAPLWPKEVLDPVLVTEGSSLILPCNPPPGLPPPLIFWMDSTMTPIVQ-DKRVSM 179 Query: 160 VDGGNLVIQDARQTDA-GRYQCIARN--AAGTRESAIATLKIHIK-PYLITGPEDVVAQT 215 G+L + DA Y+C AR ++ LK+H K P+ T D Sbjct: 180 GLNGDLYFSNVMAKDAHNEYKCNARCRLTQTIQQKNPFILKVHTKEPFNDTSHNDTDPYG 239 Query: 216 GSSVTFQCRVGG-DPL----PDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEY 270 + ++ PL V R GG P LD L N ++ E Sbjct: 240 EDEEDARGQISQISPLIVKRASVHPVRCCGGKERP--DQDGLDMPREGLVNKMVERYLES 297 Query: 271 SCEAEN-SVGAVSASGYLTVYDP--PSINLSP----NSVNVESGNVARFTCTATGRPEPT 323 + +AE+ G + G P++ LSP +S V G C A G P PT Sbjct: 298 NSQAEDPEEGLMDGCGRSRKLPQTMPTL-LSPTGSQSSKMVLRGQQLLLECIAAGVPTPT 356 Query: 324 MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383 + W +G + + + ++ T + GV+ + VC A+N+ GS + Sbjct: 357 IKWYRKGG-DLPERKVKFENFNKTLLVVGVS---------EEDAGEYVCMAINHQGS--I 404 Query: 384 RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG---EALIQ 440 R + V + P + P+N L C A P+P I W G E+ Q Sbjct: 405 RHSILV---QVKAAPYWLDKPTNLVLAPNENGRLVCRANGNPKPNIQWLINGQPIESSPQ 461 Query: 441 NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483 N R+V D T++ + + S Y C AS+++G Y+ S A + Sbjct: 462 NPSRDVLGD-TIIFRSVQMGSSAVYQCNASNQYG-YLLSNAFV 502 Score = 50.4 bits (115), Expect = 3e-04 Identities = 34/126 (26%), Positives = 57/126 (45%), Gaps = 4/126 (3%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753 ++ L ++KY+ F++ +EG PSN+ T + VPD P + N TVHL+W Sbjct: 911 LSELVPFSKYKMFMVVANTHYEGPPSNTVEFTTKEGVPDAPRF-FTINRKNVDTVHLEWG 969 Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAE 813 P L+ NGI+ GY + ++ + T + T + Y ++A Sbjct: 970 KP-LE-PNGILIGYQLKYQTVN-GSTVGRAQFETFLPNVTEFTLRLPDRAARYKFYLSAV 1026 Query: 814 TIIGLG 819 T +G G Sbjct: 1027 TQVGSG 1032 >UniRef50_A1Z920 Cluster: CG8581-PA, isoform A; n=8; Diptera|Rep: CG8581-PA, isoform A - Drosophila melanogaster (Fruit fly) Length = 1526 Score = 109 bits (261), Expect = 6e-22 Identities = 75/259 (28%), Positives = 121/259 (46%), Gaps = 18/259 (6%) Query: 42 AIRWYKGGVLVVSDTHRSI-LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNAT 100 +++W K + + D R + LP G L SD G Y C T+ + S Sbjct: 179 SVQWLKDDLPLPLDKLRMVVLPNGALEIDEVGP----SDRGSYQCNVTSGSSSRLSSKTN 234 Query: 101 LHVAV---------LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLF 151 L++ + F + P K +GDTV L+C+ G P+P + W +NG L F Sbjct: 235 LNIKKPSDPGAENSVAPSFLVGPSPKTVREGDTVTLDCVA-NGVPKPQIKWLRNGMDLDF 293 Query: 152 -DGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED 210 D DSR +V G+L I A D+G YQC A N + + A AT+++ P I P+D Sbjct: 294 NDLDSRFSIVGTGSLQISSAEDIDSGNYQCRASNTVDSLD-AQATVQVQEPPKFIKAPKD 352 Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEY 270 A +C + G P P + W ++ G P ++++D +L++ ++ +D G + Sbjct: 353 TTAHEKDEPELKCDIWGKPKPVIRWLKN-GDLITPNDYMQLVDGHNLKILGLLNSDAGMF 411 Query: 271 SCEAENSVGAVSASGYLTV 289 C N+ G+V A+ L V Sbjct: 412 QCVGTNAAGSVHAAARLRV 430 Score = 97.1 bits (231), Expect = 3e-18 Identities = 81/314 (25%), Positives = 129/314 (41%), Gaps = 28/314 (8%) Query: 40 SPAIRWYKG----GVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT-NSYGTA 94 S +IRW +G +++V DT R+ L G L+ R G Y C T G+ Sbjct: 75 SVSIRW-RGPDGQDLVIVGDTFRTQLKNGSLYISSVEENR--GLTGAYQCLLTAEGVGSI 131 Query: 95 RSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPEP----NVYWKKNGQTL 149 SR A VA++R+ + + G T C+ + + +V W K+ L Sbjct: 132 LSRPAL--VAIVRQPDLNQDFLETYLLPGQTAYFRCMLGEANWQEGVKHSVQWLKDDLPL 189 Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH---------- 199 D RM ++ G L I + +D G YQC + + +R S+ L I Sbjct: 190 PLD-KLRMVVLPNGALEIDEVGPSDRGSYQCNVTSGSSSRLSSKTNLNIKKPSDPGAENS 248 Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPLGRVKVLDDGSL 257 + P + GP + G +VT C G P P + W R+ N R ++ GSL Sbjct: 249 VAPSFLVGPSPKTVREGDTVTLDCVANGVPKPQIKWLRNGMDLDFNDLDSRFSIVGTGSL 308 Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317 ++ + D G Y C A N+V ++ A + V +PP +P + C Sbjct: 309 QISSAEDIDSGNYQCRASNTVDSLDAQATVQVQEPPKFIKAPKDTTAHEKDEPELKCDIW 368 Query: 318 GRPEPTMFWSVEGN 331 G+P+P + W G+ Sbjct: 369 GKPKPVIRWLKNGD 382 Score = 83.8 bits (198), Expect = 3e-14 Identities = 65/200 (32%), Positives = 96/200 (48%), Gaps = 13/200 (6%) Query: 2 SDDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS---DTHR 58 SD + AP + P TV TL+C A G P P I+W + G+ + D+ Sbjct: 241 SDPGAENSVAPSFLVGPSPKTVREGDTVTLDCVANGVPKPQIKWLRNGMDLDFNDLDSRF 300 Query: 59 SILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ 118 SI+ G L A D+G Y C A+N+ + ++ AT+ V +F P+ Sbjct: 301 SIVGTGSLQISSAED----IDSGNYQCRASNTVDSLDAQ-ATVQVQE-PPKFIKAPKDTT 354 Query: 119 SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY 178 + + D L+C G P+P + W KNG L + M LVDG NL I +DAG + Sbjct: 355 AHEKDEPELKC-DIWGKPKPVIRWLKNGD--LITPNDYMQLVDGHNLKILGLLNSDAGMF 411 Query: 179 QCIARNAAGTRESAIATLKI 198 QC+ NAAG+ +A A L++ Sbjct: 412 QCVGTNAAGSVHAA-ARLRV 430 Score = 83.0 bits (196), Expect = 4e-14 Identities = 96/398 (24%), Positives = 155/398 (38%), Gaps = 47/398 (11%) Query: 110 FRLEPESKQSAQGDTVVLEC-----LPPRGSPEPN------VYWK-KNGQTLLFDGDSRM 157 F LEP+ +G +V+L+C + G + N + W+ +GQ L+ GD+ Sbjct: 37 FTLEPQDAVVPEGHSVLLQCAGTASIGRGGKSKSNLPSSVSIRWRGPDGQDLVIVGDTFR 96 Query: 158 HLVDGGNLVIQDARQTDA--GRYQCI-ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQ 214 + G+L I + G YQC+ G+ S A + I +P L + Sbjct: 97 TQLKNGSLYISSVEENRGLTGAYQCLLTAEGVGSILSRPALVAIVRQPDLNQDFLETYLL 156 Query: 215 TGSSVTFQCRVGGDPLPD-----VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGE 269 G + F+C +G + V W + + R+ VL +G+L +D V +D G Sbjct: 157 PGQTAYFRCMLGEANWQEGVKHSVQWLKDDLPLPLDKLRMVVLPNGALEIDEVGPSDRGS 216 Query: 270 YSCEAEN-SVGAVSASGYLTVYDP----------PSINLSPNSVNVESGNVARFTCTATG 318 Y C + S +S+ L + P PS + P+ V G+ C A G Sbjct: 217 YQCNVTSGSSSRLSSKTNLNIKKPSDPGAENSVAPSFLVGPSPKTVREGDTVTLDCVANG 276 Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD--GVTVLTINDTDKNDSRNTIVCSAVN 376 P+P + W + GM D + F G L I+ + DS N C A N Sbjct: 277 VPKPQIKW--------LRNGMDLDFNDLDSRFSIVGTGSLQISSAEDIDSGN-YQCRASN 327 Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436 S + + V + PP P + T K C P+P+I W G+ Sbjct: 328 TVDSLDAQATVQV-----QEPPKFIKAPKDTTAHEKDEPELKCDIWGKPKPVIRWLKNGD 382 Query: 437 ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 + N + + L + L SD+G + CV ++ G Sbjct: 383 LITPNDYMQLVDGHNLKILGLLNSDAGMFQCVGTNAAG 420 Score = 74.9 bits (176), Expect = 1e-11 Identities = 82/323 (25%), Positives = 134/323 (41%), Gaps = 43/323 (13%) Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562 LP P + V VTLSW + + + ++ Y V NN+ R + Sbjct: 610 LPSQPRDLVAQIVKSRFVTLSWVEPLQ-NAGDVVYYTVYY------KMNNSEREQK---- 658 Query: 563 IARRVHQTHYV-VKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVS 621 + + H V ++SL+PG TY F V + G SG S V+ + N G Sbjct: 659 MVTKSHDDQQVNIQSLLPGRTYQFRVEANTNFG-SGASSAPLEVSTQPEVNI----AGPP 713 Query: 622 NSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMK 681 + E + V+ E T + + +K +Y+ D+ Y Sbjct: 714 RNFEGYARSHKEIYVKWEEPTVTNGEILKYR-------------VYYSENDSGADLYHDS 760 Query: 682 TILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMF 741 T L + +T LR +T Y ++PF + G S +T P PP N+ + Sbjct: 761 TALEA------VLTELRPHTDYVISVVPFNRNGMGDSSAEIRVKTFSSTPSEPPNNVTLE 814 Query: 742 ILNTTTVHLKWSPPELQLQNGIITGYNV-VVNWLDVPANKSMVAINTTVHQATSLIMTNL 800 + +++++ + W PP + +NG ITGY + + D P KS A N + ++NL Sbjct: 815 VTSSSSITVHWEPPAEEDRNGQITGYKIRYRKFKDAPQVKSTPA-NIRYFE-----LSNL 868 Query: 801 TSGVSYSVQIAAETIIGLGPFSQ 823 Y V+IAA T+ G GPF++ Sbjct: 869 DRNAEYQVKIAAMTVNGSGPFTE 891 Score = 55.2 bits (127), Expect = 1e-05 Identities = 51/191 (26%), Positives = 83/191 (43%), Gaps = 17/191 (8%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPP--INIEMFILNTTTVHLK 751 I LR T+YEF + + E S S + T +VP PP + + + +N TV ++ Sbjct: 1069 INDLRPNTQYEFAVKVVKGRRESSWSMSVLNSTYQNVPVTPPREVTVRLDEMNPPTVIVQ 1128 Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811 W PP+ L G ITGYN+ D ++ + T L++ NL +Y ++ Sbjct: 1129 WIPPKHTL--GQITGYNIYYT-TDTTKRDRDWSVEAFAGEETMLMLPNLKPYTTYYFKVQ 1185 Query: 812 AETIIGL--GPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETWFYFLIGAIV 869 A T G PFS V + S +V + E +A E Y +I A Sbjct: 1186 ARTTKGANNAPFSALVSYT-TSAAVTMQ---------EPDTIAKGIDNEKLLYIIIAATA 1235 Query: 870 LFKIIVIAGII 880 + ++V+ G++ Sbjct: 1236 VVLLVVLLGVL 1246 Score = 35.5 bits (78), Expect = 8.9 Identities = 38/152 (25%), Positives = 60/152 (39%), Gaps = 13/152 (8%) Query: 677 EYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVP-DGPP 735 E E K + S+D I SL Y+F + G S T +V GPP Sbjct: 654 EREQKMVTKSHDDQQVNIQSLLPGRTYQFRVEANTNFGSGASSAPLEVSTQPEVNIAGPP 713 Query: 736 INIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSL 795 N E + + +++KW P + NG I Y V + D A+ H +T+L Sbjct: 714 RNFEGYARSHKEIYVKWEEP--TVTNGEILKYRVYYSENDSGAD--------LYHDSTAL 763 Query: 796 --IMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825 ++T L Y + + G+G S ++ Sbjct: 764 EAVLTELRPHTDYVISVVPFNRNGMGDSSAEI 795 >UniRef50_O94898 Cluster: Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor; n=10; Euteleostomi|Rep: Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor - Homo sapiens (Human) Length = 1065 Score = 109 bits (261), Expect = 6e-22 Identities = 70/245 (28%), Positives = 113/245 (46%), Gaps = 17/245 (6%) Query: 106 LREEFRLEPESKQSAQGDTVVLECLPPRGSPEP-NVYWKKNGQTLLFDGDSR---MHLVD 161 L+ + R PE+ + +G V L C S P + W+K+ + +L+D D+ + Sbjct: 496 LKPQIRTHPETIIALRGMNVTLTCTAVSSSDSPMSTVWRKDSE-ILYDVDTENFVRYWQQ 554 Query: 162 GGN-------LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQ 214 G L + + TD G+YQCI N G+ S A L ++ P + P D+ + Sbjct: 555 AGEALEYTSILHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEMPSFLKTPMDLTIR 614 Query: 215 TGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL----DDGSLRLDNVILADEGEY 270 TG+ +C G P P + W++ GG + P R + + +D + NV + D G Y Sbjct: 615 TGAMARLECAAEGHPAPQISWQKD-GGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIY 673 Query: 271 SCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330 SC A+N+ G +SA+ LTV + PS V G A C A G P P + W+ + Sbjct: 674 SCMAQNTAGGLSANASLTVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDD 733 Query: 331 NRTII 335 ++ Sbjct: 734 GPLLV 738 Score = 94.7 bits (225), Expect = 1e-17 Identities = 88/305 (28%), Positives = 127/305 (41%), Gaps = 14/305 (4%) Query: 12 PYIIEQPLDVTVARHQPATLNCRA-GGSPSP-AIRWYKGG-VLVVSDTHRSIL---PAG- 64 P I P + R TL C A S SP + W K +L DT + AG Sbjct: 498 PQIRTHPETIIALRGMNVTLTCTAVSSSDSPMSTVWRKDSEILYDVDTENFVRYWQQAGE 557 Query: 65 GLFFLRATH--GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122 L + H +D G Y C TN +G+ S+ A L V + F P G Sbjct: 558 ALEYTSILHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEM-PSFLKTPMDLTIRTG 616 Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQT-LLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQC 180 LEC G P P + W+K+G T + RMH++ ++ I + + D G Y C Sbjct: 617 AMARLECAA-EGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSC 675 Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 +A+N AG SA A+L + P I ED G + QC GG P P + W + G Sbjct: 676 MAQNTAGGL-SANASLTVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDG 734 Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300 + + L + + L D G+Y+C N++G YL V P+ + S + Sbjct: 735 PLLVTERHFFAAANQLLIIVDAGLEDAGKYTCIMSNTLGTERGHIYLNVISSPNCDSSQS 794 Query: 301 SVNVE 305 S+ E Sbjct: 795 SIGHE 799 Score = 93.5 bits (222), Expect = 3e-17 Identities = 65/194 (33%), Positives = 93/194 (47%), Gaps = 16/194 (8%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG---VLVVSDTHRSILP 62 +T E P ++ P+D+T+ A L C A G P+P I W K G + ++P Sbjct: 596 LTVNEMPSFLKTPMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMP 655 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQ 121 +FF+ + ++ D G+Y C A N+ G S NA+L VL + P E K + Sbjct: 656 EDDVFFI--ANVKI-EDMGIYSCMAQNTAG-GLSANASL--TVLETPSFIRPLEDKTVTR 709 Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQ 179 G+T VL+C+ GSP P + W K+ LL + H N L+I DA DAG+Y Sbjct: 710 GETAVLQCI-AGGSPAPRLNWTKDDGPLLV---TERHFFAAANQLLIIVDAGLEDAGKYT 765 Query: 180 CIARNAAGTRESAI 193 CI N GT I Sbjct: 766 CIMSNTLGTERGHI 779 Score = 88.2 bits (209), Expect = 1e-15 Identities = 77/289 (26%), Positives = 115/289 (39%), Gaps = 25/289 (8%) Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRV--GGDPLPDVLWRRSA----GGGNMPLGRV---- 249 +KP + T PE ++A G +VT C D +WR+ + R Sbjct: 496 LKPQIRTHPETIIALRGMNVTLTCTAVSSSDSPMSTVWRKDSEILYDVDTENFVRYWQQA 555 Query: 250 -KVLDDGS-LRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSVNVES 306 + L+ S L L NV DEG+Y C N G+ S LTV + PS +P + + + Sbjct: 556 GEALEYTSILHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEMPSFLKTPMDLTIRT 615 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 G +AR C A G P P + W +G FP + H D + + K + Sbjct: 616 GAMARLECAAEGHPAPQISWQKDGGTD--FPAARERRMHVMPEDDVFFIANV----KIED 669 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426 C A N AG LTV P+ ++T+ AV C A +P Sbjct: 670 MGIYSCMAQNTAGGLSANASLTVLETPSFIRPL-----EDKTVTRGETAVLQCIAGGSPA 724 Query: 427 PIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 P + W + G L+ + L++ D D+G YTC+ S+ G Sbjct: 725 PRLNWTKDDGPLLVTERHFFAAANQLLIIVDAGLEDAGKYTCIMSNTLG 773 >UniRef50_Q61YY0 Cluster: Putative uncharacterized protein CBG03355; n=1; Caenorhabditis briggsae|Rep: Putative uncharacterized protein CBG03355 - Caenorhabditis briggsae Length = 1055 Score = 108 bits (260), Expect = 8e-22 Identities = 102/423 (24%), Positives = 170/423 (40%), Gaps = 40/423 (9%) Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137 S G Y C A+N +GTA S L + L + E + + +G+++ L C PPRG P Sbjct: 73 SHQGYYQCFASNIFGTALSNKMHLRLGSLEHFPKREIQILKIKEGESLTLNCTPPRGIPP 132 Query: 138 PNVYW---KKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGR---YQCIARNAAGTRE 190 P + W + +++ SR VD G L +D Y+C A + E Sbjct: 133 PKIIWLYRSLDDSSVIETIRSRHITVDNNGRLHFSSVELSDGKPTLVYECAATSPILRGE 192 Query: 191 SAIAT-LKIHIKPY---------LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 +++ I+P L P +V + G + QC GG PLP + W S Sbjct: 193 YRSGDRVQLDIEPSQDKSYPVKKLSVSPSEVTVRAGGQLKLQCVFGGRPLPTIFW--SKV 250 Query: 241 GGNMPLGRVKVL-----DDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294 G +P R+K L D G SL ++NV D G Y C + V V+ + V P Sbjct: 251 DGELPKSRIKDLTTHESDFGRSLIVENVHPDDAGVYECRGRHLVHTVN----VRVMAAPF 306 Query: 295 INLSP-NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353 P +++ + C A G+P P + WS+ G ++ D + D Sbjct: 307 WEFEPPRDISLPEESTGELECLAGGQPTPIITWSMNGK---FLHELAEDSRRV--LLDHG 361 Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413 +L + + + C+A N G F + V + P + + + S Sbjct: 362 RILRVRSLNHDLDTGVYQCNASNPLGYVFANAFVHVRA---HAPFFRMPAARHWKVVLHS 418 Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQ--NHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471 + C PE I+ W + +Q + + + T ++ D++ +D G Y C S+ Sbjct: 419 TVILDCDVDAAPEAIVRWVDADDRPLQVVEGKNKLFPNHTFMIYDVNSADEGLYYCNVSN 478 Query: 472 RHG 474 ++G Sbjct: 479 KYG 481 Score = 70.1 bits (164), Expect = 3e-10 Identities = 81/281 (28%), Positives = 107/281 (38%), Gaps = 22/281 (7%) Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77 P +VTV L C GG P P I W K + + + F VH Sbjct: 220 PSEVTVRAGGQLKLQCVFGGRPLPTIFWSKVDGELPKSRIKDLTTHESDFGRSLIVENVH 279 Query: 78 -SDAGVYWCEATNSYGTARSRNATLHVAVLREEF-RLEPESKQS-AQGDTVVLECLPPRG 134 DAGVY C R T++V V+ F EP S + T LECL G Sbjct: 280 PDDAGVYECR-------GRHLVHTVNVRVMAAPFWEFEPPRDISLPEESTGELECL-AGG 331 Query: 135 SPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNL--VIQDARQTDAGRYQCIARNAAG-TRE 190 P P + W NG+ L DSR L+D G + V D G YQC A N G Sbjct: 332 QPTPIITWSMNGKFLHELAEDSRRVLLDHGRILRVRSLNHDLDTGVYQCNASNPLGYVFA 391 Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL---- 246 +A ++ H + + S+V C V P V W + PL Sbjct: 392 NAFVHVRAHAPFFRMPAARHWKVVLHSTVILDCDVDAAPEAIVRW---VDADDRPLQVVE 448 Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYL 287 G+ K+ + + + +V ADEG Y C N G A+ L Sbjct: 449 GKNKLFPNHTFMIYDVNSADEGLYYCNVSNKYGINRATNRL 489 Score = 68.1 bits (159), Expect = 1e-09 Identities = 94/371 (25%), Positives = 156/371 (42%), Gaps = 44/371 (11%) Query: 142 WKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199 W K+G+ + D + + G++V + G YQC A N GT S L++ Sbjct: 40 WLKDGEPFEINSDDVVWQKESQSGSIVFMKPHISHQGYYQCFASNIFGTALSNKMHLRLG 99 Query: 200 IKPYLITGPEDVVA-QTGSSVTFQCRVG-GDPLPDVLWR-RSAGGGNM----PLGRVKVL 252 + ++ + G S+T C G P P ++W RS ++ + V Sbjct: 100 SLEHFPKREIQILKIKEGESLTLNCTPPRGIPPPKIIWLYRSLDDSSVIETIRSRHITVD 159 Query: 253 DDGSLRLDNVILADEGE---YSCEAENSV--GAVSASGYLTVYDPPS---------INLS 298 ++G L +V L+D Y C A + + G + + + PS +++S Sbjct: 160 NNGRLHFSSVELSDGKPTLVYECAATSPILRGEYRSGDRVQLDIEPSQDKSYPVKKLSVS 219 Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWS-VEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 P+ V V +G + C GRP PT+FWS V+G P SR K T D L Sbjct: 220 PSEVTVRAGGQLKLQCVFGGRPLPTIFWSKVDGE----LP-KSRIKDLTTHESDFGRSLI 274 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417 + + +D+ C + + VR + + PP I +LP +S Sbjct: 275 VENVHPDDA-GVYECRGRHLVHTVNVR-VMAAPFWEFEPPRDI-------SLPEESTGEL 325 Query: 418 PCTAICTPEPIIAWYFEGE---ALIQNHRRNVTNDGTLV-LKDLDKS-DSGTYTCVASSR 472 C A P PII W G+ L ++ RR + + G ++ ++ L+ D+G Y C AS+ Sbjct: 326 ECLAGGQPTPIITWSMNGKFLHELAEDSRRVLLDHGRILRVRSLNHDLDTGVYQCNASNP 385 Query: 473 HGKYVWSGALL 483 G YV++ A + Sbjct: 386 LG-YVFANAFV 395 Score = 68.1 bits (159), Expect = 1e-09 Identities = 51/177 (28%), Positives = 76/177 (42%), Gaps = 10/177 (5%) Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL---VVSDTHRSILPAGGLFFLRAT 72 E P D+++ L C AGG P+P I W G + D+ R +L G + +R+ Sbjct: 310 EPPRDISLPEESTGELECLAGGQPTPIITWSMNGKFLHELAEDSRRVLLDHGRILRVRSL 369 Query: 73 HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTVVLECL 130 + + D GVY C A+N G + NA +HV FR+ P ++ + TV+L+C Sbjct: 370 NHDL--DTGVYQCNASNPLGYVFA-NAFVHVRAHAPFFRM-PAARHWKVVLHSTVILDC- 424 Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 +PE V W L + + L +I D D G Y C N G Sbjct: 425 DVDAAPEAIVRWVDADDRPLQVVEGKNKLFPNHTFMIYDVNSADEGLYYCNVSNKYG 481 >UniRef50_UPI0000D55E60 Cluster: PREDICTED: similar to CG32796-PB, isoform B; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG32796-PB, isoform B - Tribolium castaneum Length = 827 Score = 108 bits (259), Expect = 1e-21 Identities = 80/258 (31%), Positives = 115/258 (44%), Gaps = 15/258 (5%) Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139 AG Y C A S L +A + E E G+TV C PP +PEP Sbjct: 110 AGDYQCLAYYGASVVASIPWRLTIANISEFPPQEKIDVTVIPGNTVNWRCEPPEANPEPY 169 Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA-TLKI 198 + + KNG + V +L+I + ++G Y C A N + S + LK+ Sbjct: 170 IDYHKNGVYV-----PPFVQVVTKSLIIPNVTSGNSGSYTCKAGNVCTEKFSPVLFNLKV 224 Query: 199 HIK-----PYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL 252 + P I P V T G V +C G+PLP V+WR+ G +P GR + L Sbjct: 225 DKRAPREPPKFIVRPRSVYNVTKGDKVLLECSAVGNPLPKVVWRKITG--IIPEGRSE-L 281 Query: 253 DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARF 312 G L + N+ +D G Y C +NS+G V S L + P+IN +S++V G Sbjct: 282 TPGGLIIKNISASDNGIYECTHDNSLGKVVHSITLNYNEAPTINCPQDSIDVNQGEDLEL 341 Query: 313 TCTATGRPEPTMFWSVEG 330 CT TG P+P + W + G Sbjct: 342 ECTVTGNPDPEITWFLNG 359 Score = 64.5 bits (150), Expect = 2e-08 Identities = 55/186 (29%), Positives = 81/186 (43%), Gaps = 14/186 (7%) Query: 10 EAPYIIEQPLDV-TVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68 E P I +P V V + L C A G+P P + W K + + RS L GGL Sbjct: 231 EPPKFIVRPRSVYNVTKGDKVLLECSAVGNPLPKVVWRK--ITGIIPEGRSELTPGGLII 288 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128 + SD G+Y C NS G + TL+ +S QG+ + LE Sbjct: 289 KNISA----SDNGIYECTHDNSLGKV-VHSITLNYNEA-PTINCPQDSIDVNQGEDLELE 342 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188 C G+P+P + W NG D+++ + +G + + + AG Q ARN AGT Sbjct: 343 CTVT-GNPDPEITWFLNG---FVTKDNKI-ITEGNKIFFKPTEKRHAGNLQVFARNIAGT 397 Query: 189 RESAIA 194 S+I+ Sbjct: 398 VYSSIS 403 Score = 40.3 bits (90), Expect = 0.31 Identities = 36/124 (29%), Positives = 50/124 (40%), Gaps = 7/124 (5%) Query: 359 NDTDKNDSRNTIVCSAVNYAGSSF--VRGKLTVTSDDDRPPP-IITNGPSNQTLPIKSMA 415 N T N T C A N F V L V R PP I S + Sbjct: 194 NVTSGNSGSYT--CKAGNVCTEKFSPVLFNLKVDKRAPREPPKFIVRPRSVYNVTKGDKV 251 Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 + C+A+ P P + W + +I R +T G L++K++ SD+G Y C + GK Sbjct: 252 LLECSAVGNPLPKVVWR-KITGIIPEGRSELTPGG-LIIKNISASDNGIYECTHDNSLGK 309 Query: 476 YVWS 479 V S Sbjct: 310 VVHS 313 >UniRef50_Q17AC3 Cluster: Leucine-rich transmembrane protein; n=2; Culicidae|Rep: Leucine-rich transmembrane protein - Aedes aegypti (Yellowfever mosquito) Length = 743 Score = 108 bits (259), Expect = 1e-21 Identities = 82/289 (28%), Positives = 127/289 (43%), Gaps = 23/289 (7%) Query: 113 EPESKQSAQGDTVVLECLPPRGSPEPNVY-WKKNGQTLLFDGDSRMHLV-DGGN-----L 165 EP+++ +G V L C +P+ + WK + L G L D G L Sbjct: 415 EPKTQFGIRGTNVTLVCTATSTAPDVMTFKWKHDNLELPDSGSIVTQLNNDNGTVGTTQL 474 Query: 166 VIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV 225 I + + AG+YQCI NA G S + + P+ P D+ Q G C Sbjct: 475 TIPNIQNGAAGKYQCIITNAYGVVYSQKVKVTVGTFPFFKKTPSDISVQAGKMARLDCAA 534 Query: 226 GGDPLPDVLWRRSAGGGNMPLGRVKVL----DDGSLRLDNVILADEGEYSCEAENSVGAV 281 GDP P + W + GG + P + + + DDG+ + N + D G Y+C AEN+ G + Sbjct: 535 AGDPKPQISWEKD-GGNDFPAAKDRRMHISADDGAFFIMNAQIVDMGVYTCSAENAAGVI 593 Query: 282 SASGYLTVYDPPSINLSPNSVNV-ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340 AS + V + P + L P V E G C+A+G P+P + W +G P + Sbjct: 594 KASASVLVLESPML-LKPLETKVAELGTSIVLDCSASGYPKPVILWFKDGE-----PLLV 647 Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389 +++ A DG ++ + TD +D+ C N GS KL+V Sbjct: 648 TERHFIIA--DGQLMIIVK-TDFDDA-GDYECQVENEFGSQRGLMKLSV 692 Score = 100 bits (240), Expect = 2e-19 Identities = 67/219 (30%), Positives = 100/219 (45%), Gaps = 7/219 (3%) Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139 AG Y C TN+YG S+ + V F+ P G L+C G P+P Sbjct: 484 AGKYQCIITNAYGVVYSQKVKVTVGTF-PFFKKTPSDISVQAGKMARLDCAAA-GDPKPQ 541 Query: 140 VYWKKNG-QTLLFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197 + W+K+G D RMH+ D G I +A+ D G Y C A NAAG +++ + L Sbjct: 542 ISWEKDGGNDFPAAKDRRMHISADDGAFFIMNAQIVDMGVYTCSAENAAGVIKASASVLV 601 Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257 + P L+ E VA+ G+S+ C G P P +LW + G + R ++ DG L Sbjct: 602 LE-SPMLLKPLETKVAELGTSIVLDCSASGYPKPVILWFKD-GEPLLVTERHFIIADGQL 659 Query: 258 RLD-NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295 + D G+Y C+ EN G+ L+V + P + Sbjct: 660 MIIVKTDFDDAGDYECQVENEFGSQRGLMKLSVIEGPEL 698 Score = 90.2 bits (214), Expect = 3e-16 Identities = 61/188 (32%), Positives = 91/188 (48%), Gaps = 12/188 (6%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG---VLVVSDTHRSILP 62 VT G P+ + P D++V + A L+C A G P P I W K G D I Sbjct: 505 VTVGTFPFFKKTPSDISVQAGKMARLDCAAAGDPKPQISWEKDGGNDFPAAKDRRMHISA 564 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQ 121 G FF+ + ++ D GVY C A N+ G + A+ V VL L+P E+K + Sbjct: 565 DDGAFFI--MNAQI-VDMGVYTCSAENAAGVIK---ASASVLVLESPMLLKPLETKVAEL 618 Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181 G ++VL+C G P+P + W K+G+ LL + + DG ++I DAG Y+C Sbjct: 619 GTSIVLDC-SASGYPKPVILWFKDGEPLLVT-ERHFIIADGQLMIIVKTDFDDAGDYECQ 676 Query: 182 ARNAAGTR 189 N G++ Sbjct: 677 VENEFGSQ 684 Score = 89.4 bits (212), Expect = 5e-16 Identities = 72/286 (25%), Positives = 116/286 (40%), Gaps = 24/286 (8%) Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL---WRRS------AGGGNMPLGRVK- 250 KP+LI P+ G++VT C PDV+ W+ +G L Sbjct: 409 KPHLIDEPKTQFGIRGTNVTLVC-TATSTAPDVMTFKWKHDNLELPDSGSIVTQLNNDNG 467 Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAV-SASGYLTVYDPPSINLSPNSVNVESGNV 309 + L + N+ G+Y C N+ G V S +TV P +P+ ++V++G + Sbjct: 468 TVGTTQLTIPNIQNGAAGKYQCIITNAYGVVYSQKVKVTVGTFPFFKKTPSDISVQAGKM 527 Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369 AR C A G P+P + W +G FP + H +A ++ D Sbjct: 528 ARLDCAAAGDPKPQISWEKDGGND--FPAAKDRRMHISADDGAFFIMNAQIVDMG----V 581 Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429 CSA N AG + V P++ + + + V C+A P+P+I Sbjct: 582 YTCSAENAAGVIKASASVLVLES-----PMLLKPLETKVAELGTSIVLDCSASGYPKPVI 636 Query: 430 AWYFEGEALIQNHRRNVTNDGTL-VLKDLDKSDSGTYTCVASSRHG 474 W+ +GE L+ R + DG L ++ D D+G Y C + G Sbjct: 637 LWFKDGEPLLVTERHFIIADGQLMIIVKTDFDDAGDYECQVENEFG 682 Score = 47.6 bits (108), Expect = 0.002 Identities = 31/88 (35%), Positives = 47/88 (53%), Gaps = 7/88 (7%) Query: 10 EAPYIIEQPLDVTVARHQPA-TLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLF 67 E+P +++ PL+ VA + L+C A G P P I W+K G L+V++ H I+ G L Sbjct: 603 ESPMLLK-PLETKVAELGTSIVLDCSASGYPKPVILWFKDGEPLLVTERH-FIIADGQLM 660 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTAR 95 + T DAG Y C+ N +G+ R Sbjct: 661 IIVKTD---FDDAGDYECQVENEFGSQR 685 Score = 45.6 bits (103), Expect = 0.008 Identities = 56/216 (25%), Positives = 90/216 (41%), Gaps = 14/216 (6%) Query: 281 VSASGYLTVYDPPSINL--SPNSVNVESGNVARFTCTATGR-PEPTMFWSVEGNRTIIFP 337 +SAS + + YD P +L P + G CTAT P+ F N + Sbjct: 397 LSASNF-SCYDSPKPHLIDEPKTQFGIRGTNVTLVCTATSTAPDVMTFKWKHDNLELPDS 455 Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397 G + + G T LTI + +N + C N G + + K+ VT Sbjct: 456 GSIVTQLNNDNGTVGTTQLTIPNI-QNGAAGKYQCIITNAYGVVYSQ-KVKVTVGTF--- 510 Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE---ALIQNHRRNVT-NDGTLV 453 P PS+ ++ MA C A P+P I+W +G ++ R +++ +DG Sbjct: 511 PFFKKTPSDISVQAGKMARLDCAAAGDPKPQISWEKDGGNDFPAAKDRRMHISADDGAFF 570 Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLV-DSPI 488 + + D G YTC A + G S ++LV +SP+ Sbjct: 571 IMNAQIVDMGVYTCSAENAAGVIKASASVLVLESPM 606 >UniRef50_UPI0000DB720E Cluster: PREDICTED: similar to zormin CG33484-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to zormin CG33484-PA - Apis mellifera Length = 3593 Score = 107 bits (258), Expect = 1e-21 Identities = 122/506 (24%), Positives = 196/506 (38%), Gaps = 55/506 (10%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 D TV + T C G P+P + WYK G+ ++++ G+ L D Sbjct: 1742 DATVQEGEKFTFQCNLIGQPTPEVIWYKDGISILNNPDYLTTYIHGICTL-TIEETFAED 1800 Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREE-------FRLEPESKQSAQGDTVVLECLPP 132 + Y C+A N G+A + +ATL V E F E + + + + L C Sbjct: 1801 SAKYTCKAFNIAGSAET-SATLTVKETAPEEQPSSPVFVKELMASVALENSSHQLNC-TV 1858 Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRES 191 +G+P P V W KN + D + +G L ++ D Y C A N G + S Sbjct: 1859 KGNPLPTVQWFKNDVNIDNSPDYVITYNNGEAVLKFEEVFLEDKATYTCKATNKLG-QAS 1917 Query: 192 AIATLKIH------IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 A L + KPY +T + + + G V +C G+P+P + W Sbjct: 1918 TSAFLDVEPAEFTSEKPYFVTPLSNAMGRAGQRVKLECEAKGNPMPALTWYHDGRPVEES 1977 Query: 246 LGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGA------VSASGYL---------- 287 + +D G SL + D G Y+ A+N G VS G L Sbjct: 1978 MNLKIQMDGGRTSLVISEAFAKDAGCYTVVAKNEAGEATVTCNVSVKGRLPHETSDSEFA 2037 Query: 288 -TVYDP--PSINLSPNSVNVESGNVARFTCTATGRPEPTMFW-------SVEGNRTIIFP 337 + +P P I + + V+ G R C G+PEP + W + ++F Sbjct: 2038 CSDMEPVVPKIQMPLKDLKVQEGLSVRLDCVIVGQPEPEVIWYHDDQPVKESADFQLLFQ 2097 Query: 338 GMSRDKYHATAVFD--GV-TVLTINDTDKNDSRNTIVCSAVNYAGS-SFVRGKLTVTSDD 393 G A D GV V+ IN + S+ T+ + V + R ++ T Sbjct: 2098 GDKCSLVIHEAFLDDAGVYKVVAINSGGEASSQCTLTVTPVTVSEKLDRARTEIEETFVA 2157 Query: 394 DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNV--TNDGT 451 PP + P++ + A+F C + P+P + W+ + + +N R + DGT Sbjct: 2158 GSPPRFV-KLPTDSLVAEGETAIFECAVVGEPKPELKWFSDSGEVTENERILIQRKEDGT 2216 Query: 452 LVLK--DLDKSDSGTYTCVASSRHGK 475 +LK D G Y A + HG+ Sbjct: 2217 SILKISSAIPEDKGNYVVKAFNEHGE 2242 Score = 95.9 bits (228), Expect = 6e-18 Identities = 135/609 (22%), Positives = 222/609 (36%), Gaps = 74/609 (12%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 +P +++ + + LNC G+P P ++W+K V + + I G L+ Sbjct: 1834 SPVFVKELMASVALENSSHQLNCTVKGNPLPTVQWFKNDVNIDNSPDYVITYNNGEAVLK 1893 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA----VLREEFRLEPESKQSAQ-GDTV 125 + D Y C+ATN G A S +A L V + + + P S + G V Sbjct: 1894 FEEVFL-EDKATYTCKATNKLGQA-STSAFLDVEPAEFTSEKPYFVTPLSNAMGRAGQRV 1951 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIAR 183 LEC +G+P P + W +G+ + + ++ + DGG +LVI +A DAG Y +A+ Sbjct: 1952 KLEC-EAKGNPMPALTWYHDGRPVEESMNLKIQM-DGGRTSLVISEAFAKDAGCYTVVAK 2009 Query: 184 NAAG-----------------TRESAIATLKIH-IKPYLITGPEDVVAQTGSSVTFQCRV 225 N AG T +S A + + P + +D+ Q G SV C + Sbjct: 2010 NEAGEATVTCNVSVKGRLPHETSDSEFACSDMEPVVPKIQMPLKDLKVQEGLSVRLDCVI 2069 Query: 226 GGDPLPDVLWRRSAGGGNMPLGRVKVL--DDGSLRLDNVILADEGEYSCEAENSVGAVSA 283 G P P+V+W + D SL + L D G Y A NS G S+ Sbjct: 2070 VGQPEPEVIWYHDDQPVKESADFQLLFQGDKCSLVIHEAFLDDAGVYKVVAINSGGEASS 2129 Query: 284 SGYLTVY----------------------DPPSINLSPNSVNVESGNVARFTCTATGRPE 321 LTV PP P V G A F C G P+ Sbjct: 2130 QCTLTVTPVTVSEKLDRARTEIEETFVAGSPPRFVKLPTDSLVAEGETAIFECAVVGEPK 2189 Query: 322 PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381 P + W + ++ DG ++L I+ D N +V A N G + Sbjct: 2190 PELKWFSDSGEV-----TENERILIQRKEDGTSILKISSAIPEDKGNYVV-KAFNEHGEA 2243 Query: 382 FVRGKLTVTS-------------DDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428 +L + S ++ P ++ + F C + P P Sbjct: 2244 KAFARLVIRSLGDFRRKEEFVKMEEKLIAPTFKERFEDRRVMEGVSTKFECIVVGKPSPK 2303 Query: 429 IAWYFEGEALI-QNHRRNVTND-GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486 I W F + ++ +V+ D L + + + +GT +CVA + GK + S L + Sbjct: 2304 IQWLFNDRPVHGKDFLVSVSGDRQVLTIPETGSTHAGTISCVAENAAGKAICSARLEIGG 2363 Query: 487 PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRE 546 + V L H + + S ++ G S +L + + Sbjct: 2364 RSVEEVRKVGEKRVVDLVERSPADEMHAASSSEKHFSSEKSEGEGESQVLTKMSQTITES 2423 Query: 547 TLSGNNTPR 555 T + T + Sbjct: 2424 TTTHKTTKK 2432 Score = 79.8 bits (188), Expect = 4e-13 Identities = 76/306 (24%), Positives = 115/306 (37%), Gaps = 25/306 (8%) Query: 188 TRESAIATLKIHIKPYL---ITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-- 241 TRE ++ + P L T P D Q G TFQC + G P P+V+W + Sbjct: 1716 TREKSVERMHKESVPPLAPEFTIPLHDATVQEGEKFTFQCNLIGQPTPEVIWYKDGISIL 1775 Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PPSINLSP 299 N + +L ++ D +Y+C+A N G+ S LTV + P SP Sbjct: 1776 NNPDYLTTYIHGICTLTIEETFAEDSAKYTCKAFNIAGSAETSATLTVKETAPEEQPSSP 1835 Query: 300 NSVNVESGNVA------RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353 V +VA + CT G P PT+ W + + +G Sbjct: 1836 VFVKELMASVALENSSHQLNCTVKGNPLPTVQWFKND------VNIDNSPDYVITYNNGE 1889 Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT-SDDDRPPPIITNGPSNQTLPIK 412 VL + D + T C A N G + L V ++ P SN Sbjct: 1890 AVLKFEEVFLED-KATYTCKATNKLGQASTSAFLDVEPAEFTSEKPYFVTPLSNAMGRAG 1948 Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVA 469 C A P P + WY +G + ++ + DG +LV+ + D+G YT VA Sbjct: 1949 QRVKLECEAKGNPMPALTWYHDGRPVEESMNLKIQMDGGRTSLVISEAFAKDAGCYTVVA 2008 Query: 470 SSRHGK 475 + G+ Sbjct: 2009 KNEAGE 2014 Score = 78.2 bits (184), Expect = 1e-12 Identities = 111/443 (25%), Positives = 173/443 (39%), Gaps = 72/443 (16%) Query: 8 SGEAPYIIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66 + E PY + PL + R Q L C A G+P PA+ WY G V + I GG Sbjct: 1930 TSEKPYFVT-PLSNAMGRAGQRVKLECEAKGNPMPALTWYHDGRPVEESMNLKIQMDGGR 1988 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLRE----EFR---LEP---- 114 L + DAG Y A N G A + N ++ + E EF +EP Sbjct: 1989 TSLVISEA-FAKDAGCYTVVAKNEAGEATVTCNVSVKGRLPHETSDSEFACSDMEPVVPK 2047 Query: 115 -----ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQ 168 + + +G +V L+C+ G PEP V W + Q + D ++ D +LVI Sbjct: 2048 IQMPLKDLKVQEGLSVRLDCVIV-GQPEPEVIWYHDDQPVKESADFQLLFQGDKCSLVIH 2106 Query: 169 DARQTDAGRYQCIARNAAGTRES----AIATLKIHIK-----------------PYLITG 207 +A DAG Y+ +A N+ G S + + + K P + Sbjct: 2107 EAFLDDAGVYKVVAINSGGEASSQCTLTVTPVTVSEKLDRARTEIEETFVAGSPPRFVKL 2166 Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDGS--LRLDNVIL 264 P D + G + F+C V G+P P++ W +G ++ +DG+ L++ + I Sbjct: 2167 PTDSLVAEGETAIFECAVVGEPKPELKWFSDSGEVTENERILIQRKEDGTSILKISSAIP 2226 Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA-------------- 310 D+G Y +A N G A L + V +E +A Sbjct: 2227 EDKGNYVVKAFNEHGEAKAFARLVIRSLGDFRRKEEFVKMEEKLIAPTFKERFEDRRVME 2286 Query: 311 ----RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366 +F C G+P P + W + +R + K +V VLTI +T + Sbjct: 2287 GVSTKFECIVVGKPSPKIQW-LFNDRPV------HGKDFLVSVSGDRQVLTIPETGSTHA 2339 Query: 367 RNTIVCSAVNYAGSSFVRGKLTV 389 TI C A N AG + +L + Sbjct: 2340 -GTISCVAENAAGKAICSARLEI 2361 Score = 67.3 bits (157), Expect = 2e-09 Identities = 56/200 (28%), Positives = 83/200 (41%), Gaps = 15/200 (7%) Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352 P + + V+ G F C G+P P + W +G + P + T G Sbjct: 1734 PEFTIPLHDATVQEGEKFTFQCNLIGQPTPEVIWYKDGISILNNPD------YLTTYIHG 1787 Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV--TSDDDRP-PPIITNGPSNQTL 409 + LTI +T DS C A N AGS+ LTV T+ +++P P+ Sbjct: 1788 ICTLTIEETFAEDSAK-YTCKAFNIAGSAETSATLTVKETAPEEQPSSPVFVKELMASVA 1846 Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT--NDGTLVLK--DLDKSDSGTY 465 S CT P P + W F+ + I N V N+G VLK ++ D TY Sbjct: 1847 LENSSHQLNCTVKGNPLPTVQW-FKNDVNIDNSPDYVITYNNGEAVLKFEEVFLEDKATY 1905 Query: 466 TCVASSRHGKYVWSGALLVD 485 TC A+++ G+ S L V+ Sbjct: 1906 TCKATNKLGQASTSAFLDVE 1925 Score = 63.3 bits (147), Expect = 4e-08 Identities = 47/178 (26%), Positives = 75/178 (42%), Gaps = 7/178 (3%) Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179 QG ++LE + G P+P++ W KNGQ L DG + + + L ++ DAGRY Sbjct: 2542 QGTDIILEGIID-GFPQPSISWSKNGQELKTKDGITITYAHNHVRLELKKVNVKDAGRYT 2600 Query: 180 CIARNAAGTRESA--IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 C A N G+ S + K P + V + G V + + G P P V W + Sbjct: 2601 CTASNEVGSASSTADLVVKKTIFPPVFGRRLQAQVVKRGERVNMEVEITGTPEPTVTWFK 2660 Query: 238 SAGGGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292 +++ G+ L +D A G+Y A N+ G + V++P Sbjct: 2661 DDVPIKERPPELRIKQQGNCYMLIIDKAEKAHAGKYMVRATNAGGEAQSIADFAVFEP 2718 Score = 55.6 bits (128), Expect = 8e-06 Identities = 56/219 (25%), Positives = 94/219 (42%), Gaps = 30/219 (13%) Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL- 61 ++ +G P ++ P D VA + A C G P P ++W+ V++ R ++ Sbjct: 2152 EETFVAGSPPRFVKLPTDSLVAEGETAIFECAVVGEPKPELKWFSDSG-EVTENERILIQ 2210 Query: 62 -PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVL-----REEF-RLEP 114 G L+ + + D G Y +A N +G A++ A L + L +EEF ++E Sbjct: 2211 RKEDGTSILKIS-SAIPEDKGNYVVKAFNEHGEAKA-FARLVIRSLGDFRRKEEFVKMEE 2268 Query: 115 -----------ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG 163 E ++ +G + EC+ G P P + W N + + G + V G Sbjct: 2269 KLIAPTFKERFEDRRVMEGVSTKFECIVV-GKPSPKIQWLFNDRPV--HGKDFLVSVSGD 2325 Query: 164 N--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200 L I + T AG C+A NAAG AI + ++ I Sbjct: 2326 RQVLTIPETGSTHAGTISCVAENAAG---KAICSARLEI 2361 Score = 54.0 bits (124), Expect = 2e-05 Identities = 45/159 (28%), Positives = 71/159 (44%), Gaps = 7/159 (4%) Query: 37 GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96 G P P+I W K G + + +I A L V DAG Y C A+N G+A S Sbjct: 2554 GFPQPSISWSKNGQELKTKDGITITYAHNHVRLELKKVNV-KDAGRYTCTASNEVGSASS 2612 Query: 97 -RNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155 + + + F +++ +G+ V +E + G+PEP V W K+ + + Sbjct: 2613 TADLVVKKTIFPPVFGRRLQAQVVKRGERVNME-VEITGTPEPTVTWFKD-DVPIKERPP 2670 Query: 156 RMHLVDGGN---LVIQDARQTDAGRYQCIARNAAGTRES 191 + + GN L+I A + AG+Y A NA G +S Sbjct: 2671 ELRIKQQGNCYMLIIDKAEKAHAGKYMVRATNAGGEAQS 2709 Score = 49.2 bits (112), Expect = 7e-04 Identities = 32/130 (24%), Positives = 53/130 (40%), Gaps = 5/130 (3%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLD- 260 P ++ ++ G+ + + + G P P + W ++ G +RL+ Sbjct: 2529 PRFVSPLTGMIVDQGTDIILEGIIDGFPQPSISWSKNGQELKTKDGITITYAHNHVRLEL 2588 Query: 261 -NVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLSPNSVNVESGNVARFTCTA 316 V + D G Y+C A N VG+ S++ L V PP + V+ G Sbjct: 2589 KKVNVKDAGRYTCTASNEVGSASSTADLVVKKTIFPPVFGRRLQAQVVKRGERVNMEVEI 2648 Query: 317 TGRPEPTMFW 326 TG PEPT+ W Sbjct: 2649 TGTPEPTVTW 2658 Score = 37.5 bits (83), Expect = 2.2 Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 3/71 (4%) Query: 425 PEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481 P+P I+W G+ L +T N L LK ++ D+G YTC AS+ G + Sbjct: 2556 PQPSISWSKNGQELKTKDGITITYAHNHVRLELKKVNVKDAGRYTCTASNEVGSASSTAD 2615 Query: 482 LLVDSPINPNI 492 L+V I P + Sbjct: 2616 LVVKKTIFPPV 2626 >UniRef50_Q4S1C0 Cluster: Chromosome 13 SCAF14769, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 13 SCAF14769, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 620 Score = 107 bits (258), Expect = 1e-21 Identities = 62/184 (33%), Positives = 88/184 (47%), Gaps = 3/184 (1%) Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74 I +P D+TV PA L+C+A G P +RW K GV + LP G L+ + H Sbjct: 27 ITEPSDLTVLPKDPAVLDCQAHGQPPVTVRWLKNGVRLAESERVHFLPNGSLYIPKIKHT 86 Query: 75 RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRG 134 SD G Y C + N YG S+ + L +A + EF L P +G C+ Sbjct: 87 EEESDEGFYQCLSQNKYGAILSQRSHLTIARI-SEFVLHPVPAVVTEGSVARFSCV-VTS 144 Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194 SP + W+ N Q L R+ ++ G L I + R DAG+Y+C+A NAA +S A Sbjct: 145 SPPATITWEFN-QNALAVHTERITVLPNGVLQIHNVRPEDAGQYRCVAANAASRLKSKEA 203 Query: 195 TLKI 198 L + Sbjct: 204 ALTV 207 Score = 84.2 bits (199), Expect = 2e-14 Identities = 79/293 (26%), Positives = 113/293 (38%), Gaps = 27/293 (9%) Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264 IT P D+ C+ G P V W ++ G RV L +GSL + + Sbjct: 27 ITEPSDLTVLPKDPAVLDCQAHGQPPVTVRWLKN-GVRLAESERVHFLPNGSLYIPKIKH 85 Query: 265 ----ADEGEYSCEAENSVGAV-SASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGR 319 +DEG Y C ++N GA+ S +LT+ L P V G+VARF+C T Sbjct: 86 TEEESDEGFYQCLSQNKYGAILSQRSHLTIARISEFVLHPVPAVVTEGSVARFSCVVTSS 145 Query: 320 PEPTMFW-------SVEGNRTIIFPGMSRDKYHATAVFDG-VTVLTINDTDKNDSRN-TI 370 P T+ W +V R + P ++ G + N + S+ + Sbjct: 146 PPATITWEFNQNALAVHTERITVLPNGVLQIHNVRPEDAGQYRCVAANAASRLKSKEAAL 205 Query: 371 VCSAVNYAGSSFVRGK------LTVTSD------DDRPPPIITNGPSNQTLPIKSMAVFP 418 + SSF GK L V+ R P I GP N T + V Sbjct: 206 TVTRGTDPDSSFPAGKADSVLLLRVSFSCKGPHYKPRQRPRILAGPQNVTASLHQTVVLE 265 Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471 C A P PII+W I + V +G LV+ D+ SG Y C A++ Sbjct: 266 CLATGNPSPIISWSRADSKAIDVYNAKVLGNGNLVIADVSSKHSGVYLCRATT 318 Score = 77.0 bits (181), Expect = 3e-12 Identities = 57/185 (30%), Positives = 77/185 (41%), Gaps = 8/185 (4%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169 F EP D VL+C G P V W KNG L R+H + G+L I Sbjct: 26 FITEPSDLTVLPKDPAVLDC-QAHGQPPVTVRWLKNGVRLA--ESERVHFLPNGSLYIPK 82 Query: 170 ARQT----DAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV 225 + T D G YQC+++N G S + L I + P V GS F C V Sbjct: 83 IKHTEEESDEGFYQCLSQNKYGAILSQRSHLTIARISEFVLHPVPAVVTEGSVARFSCVV 142 Query: 226 GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV-SAS 284 P + W + + R+ VL +G L++ NV D G+Y C A N+ + S Sbjct: 143 TSSPPATITWEFNQNALAVHTERITVLPNGVLQIHNVRPEDAGQYRCVAANAASRLKSKE 202 Query: 285 GYLTV 289 LTV Sbjct: 203 AALTV 207 Score = 52.8 bits (121), Expect = 5e-05 Identities = 64/227 (28%), Positives = 95/227 (41%), Gaps = 34/227 (14%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 + P I+ P +VT + HQ L C A G+PSP I W + + + +L G L Sbjct: 243 QRPRILAGPQNVTASLHQTVVLECLATGNPSPIISWSRADSKAIDVYNAKVLGNGNLVI- 301 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 A HS GVY C AT T +RN T+ A L + ++++ T+VL Sbjct: 302 -ADVSSKHS--GVYLCRAT----TPGTRNYTVAAA------NLTVQGTENSREATLVL-F 347 Query: 130 LPPRGSP-----EPNVYWKKNGQTLLFDGDSRM---------HLVD----GGNLVIQDAR 171 L P P P++ + QT G +R H G LVI Sbjct: 348 LQPTNQPTSVSVPPSIVERPESQTRPRAGTARFMCQAEGVPRHASAGSRMGSKLVITQII 407 Query: 172 QTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSS 218 D YQC+A + G+ S +A L + + + P ++ A+T SS Sbjct: 408 PEDDAIYQCLAESEEGSVLS-LARLIVVMSEDRPSAPRNIHAETISS 453 Score = 49.2 bits (112), Expect = 7e-04 Identities = 40/181 (22%), Positives = 76/181 (41%), Gaps = 9/181 (4%) Query: 639 IEATPIDSKTIKLMWE--ILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITS 696 I A I S I L WE + N + I++ + + E E + ++ ND + + + Sbjct: 446 IHAETISSSAILLAWEKPLYNADKVIAYSIHYMKAEGLNNE-EYQVVI-GNDTTSYIVDD 503 Query: 697 LRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPE 756 L Y F+++ + + S+ TL+DVP P + + ++T + + W P Sbjct: 504 LESARNYSFYIVAYMPMGASRMSDQVSQHTLEDVPLRTP-ELSLTSHSSTDIQVNWQPLP 562 Query: 757 LQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETII 816 ++ G ++ Y + A S VA +T ++ L Y +++AA T Sbjct: 563 AKVSRGRLSAYRLSYR----TAADSTVASVEIPQNSTQYLLEGLQPDTIYLLRMAAATRA 618 Query: 817 G 817 G Sbjct: 619 G 619 Score = 46.0 bits (104), Expect = 0.006 Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLD 260 +P ++ GP++V A +V +C G+P P + W R A + + KVL +G+L + Sbjct: 244 RPRILAGPQNVTASLHQTVVLECLATGNPSPIISWSR-ADSKAIDVYNAKVLGNGNLVIA 302 Query: 261 NVILADEGEYSCEA 274 +V G Y C A Sbjct: 303 DVSSKHSGVYLCRA 316 Score = 45.2 bits (102), Expect = 0.011 Identities = 53/218 (24%), Positives = 86/218 (39%), Gaps = 43/218 (19%) Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT 173 P++ ++ TVVLECL G+P P + W + + ++++ + GNLVI D Sbjct: 251 PQNVTASLHQTVVLECLAT-GNPSPIISWSRADSKAIDVYNAKV--LGNGNLVIADVSSK 307 Query: 174 DAGRYQCIA-----RN---------AAGTRESAIATL-----------KIHIKPYLITGP 208 +G Y C A RN GT S ATL + + P ++ P Sbjct: 308 HSGVYLCRATTPGTRNYTVAAANLTVQGTENSREATLVLFLQPTNQPTSVSVPPSIVERP 367 Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268 E + F C+ G P R ++ G M L + +I D+ Sbjct: 368 ESQTRPRAGTARFMCQAEGVP------RHASAGSRM---------GSKLVITQIIPEDDA 412 Query: 269 EYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306 Y C AE+ G+V + L V +P +++ E+ Sbjct: 413 IYQCLAESEEGSVLSLARLIVVMSEDRPSAPRNIHAET 450 Score = 44.8 bits (101), Expect = 0.015 Identities = 48/201 (23%), Positives = 79/201 (39%), Gaps = 21/201 (10%) Query: 277 SVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF 336 SV + S+ + + S P+ + V + A C A G+P T+ W G R Sbjct: 8 SVSSPSSPPGVWSFSELSFITEPSDLTVLPKDPAVLDCQAHGQPPVTVRWLKNGVRLA-- 65 Query: 337 PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV-RGKLTVTSDDD- 394 ++ H + + I T++ C + N G+ R LT+ + Sbjct: 66 ---ESERVHFLPN-GSLYIPKIKHTEEESDEGFYQCLSQNKYGAILSQRSHLTIARISEF 121 Query: 395 --RP-PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDG 450 P P ++T G S+A F C +P I W F AL + R V +G Sbjct: 122 VLHPVPAVVTEG---------SVARFSCVVTSSPPATITWEFNQNALAVHTERITVLPNG 172 Query: 451 TLVLKDLDKSDSGTYTCVASS 471 L + ++ D+G Y CVA++ Sbjct: 173 VLQIHNVRPEDAGQYRCVAAN 193 Score = 38.7 bits (86), Expect = 0.96 Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 4/75 (5%) Query: 404 PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL----DK 459 PS+ T+ K AV C A P + W G L ++ R + +G+L + + ++ Sbjct: 30 PSDLTVLPKDPAVLDCQAHGQPPVTVRWLKNGVRLAESERVHFLPNGSLYIPKIKHTEEE 89 Query: 460 SDSGTYTCVASSRHG 474 SD G Y C++ +++G Sbjct: 90 SDEGFYQCLSQNKYG 104 Score = 37.9 bits (84), Expect = 1.7 Identities = 50/214 (23%), Positives = 81/214 (37%), Gaps = 24/214 (11%) Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352 P I P +V C ATG P P + WS ++ I D Y+A + +G Sbjct: 245 PRILAGPQNVTASLHQTVVLECLATGNPSPIISWSRADSKAI-------DVYNAKVLGNG 297 Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSF--VRGKLTVT-SDDDRPPPII-----TNGP 404 L I D S +C A ++ LTV +++ R ++ TN P Sbjct: 298 --NLVIADVSSKHS-GVYLCRATTPGTRNYTVAAANLTVQGTENSREATLVLFLQPTNQP 354 Query: 405 SNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGT 464 ++ ++P S+ P + + + E + ++ LV+ + D Sbjct: 355 TSVSVP-PSIVERPESQTRPRAGTARFMCQAEGVPRHASAGSRMGSKLVITQIIPEDDAI 413 Query: 465 YTCVASSRHGKYVWSGALLV----DSPINP-NIH 493 Y C+A S G + L+V D P P NIH Sbjct: 414 YQCLAESEEGSVLSLARLIVVMSEDRPSAPRNIH 447 >UniRef50_A4JYL6 Cluster: Sid4; n=4; Clupeocephala|Rep: Sid4 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 381 Score = 107 bits (258), Expect = 1e-21 Identities = 101/367 (27%), Positives = 145/367 (39%), Gaps = 27/367 (7%) Query: 112 LEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK-NGQTLLFDGDSRMHLVDGGNLVIQDA 170 + P + G+TV +C G+ + W+K N Q L GD+ DG L I + Sbjct: 26 VRPRTAAVRLGETVSFQCRVTSGAQPVMLEWRKINNQPL---GDNVKIGPDGAVLTIANV 82 Query: 171 RQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED-VVAQTGSSVTFQCRVGGDP 229 R + G Y+CIA NA G + + A L + P + P + + G VT C V G P Sbjct: 83 RLNNQGGYRCIATNAQG-KSTVTANLSVKHPPKVRVSPAGPLTLRVGEIVTLDCSVSGKP 141 Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 P V W R GG L SL++ + G Y C A+N G L + Sbjct: 142 RPSVSWIRRQAGGETELVSTTTDSTTSLQVTMATAENAGMYVCRAQNGEGLAEGEVELVM 201 Query: 290 YDP--PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347 P ++S + G C A+G P + WS + P + K Sbjct: 202 EGGAFPQASVSETELTAVEGQSVSMHCQASGSPAAVLSWS-----KLRAPLPWQHKV--- 253 Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407 DG T LT+++ + DS +C+A + G S +L V S PP T Sbjct: 254 ---DGGT-LTLSNVGRQDS-GQYICNATSALGFSEAYVQLEVDS-----PPYATVLTEVV 303 Query: 408 TLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467 L + C A + W G A + + T DG L + L SDSGTY C Sbjct: 304 VLRVGDALRLQCLAHGSHPIRFRWMRVGGACMSTGAES-TKDGLLRIPQLKSSDSGTYKC 362 Query: 468 VASSRHG 474 A++ G Sbjct: 363 TATNHVG 369 Score = 94.7 bits (225), Expect = 1e-17 Identities = 102/387 (26%), Positives = 159/387 (41%), Gaps = 34/387 (8%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGGLFF 68 +AP + +P V + + CR P + W K + D + I P G + Sbjct: 20 QAPSVSVRPRTAAVRLGETVSFQCRVTSGAQPVMLEWRKINNQPLGDNVK-IGPDGAV-- 76 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQ-GDTVV 126 L + R+++ G Y C ATN+ G + T +++V + R+ P + + G+ V Sbjct: 77 LTIANVRLNNQGG-YRCIATNAQGKS---TVTANLSVKHPPKVRVSPAGPLTLRVGEIVT 132 Query: 127 LECLPPRGSPEPNVYW---KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183 L+C G P P+V W + G+T L + +L + A +AG Y C A+ Sbjct: 133 LDC-SVSGKPRPSVSWIRRQAGGETELVSTTTDSTT----SLQVTMATAENAGMYVCRAQ 187 Query: 184 NAAGTRESAIA-TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242 N G E + ++ P ++ A G SV+ C+ G P + W + Sbjct: 188 NGEGLAEGEVELVMEGGAFPQASVSETELTAVEGQSVSMHCQASGSPAAVLSWSKLRA-- 245 Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302 PL +D G+L L NV D G+Y C A +++G A L V PP + V Sbjct: 246 --PLPWQHKVDGGTLTLSNVGRQDSGQYICNATSALGFSEAYVQLEVDSPPYATVLTEVV 303 Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362 + G+ R C A G W G MS A + DG +L I Sbjct: 304 VLRVGDALRLQCLAHGSHPIRFRWMRVGGAC-----MSTG---AESTKDG--LLRIPQLK 353 Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTV 389 +DS T C+A N+ GSS ++TV Sbjct: 354 SSDS-GTYKCTATNHVGSSEALSRVTV 379 Score = 46.0 bits (104), Expect = 0.006 Identities = 48/184 (26%), Positives = 77/184 (41%), Gaps = 15/184 (8%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68 G P ++T Q +++C+A GSP+ + W K + H+ GG Sbjct: 204 GAFPQASVSETELTAVEGQSVSMHCQASGSPAAVLSWSKLRA-PLPWQHK---VDGGTLT 259 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEF-RLEPESKQSAQGDTVVL 127 L + GR D+G Y C AT++ G + A + + V + + E GD + L Sbjct: 260 L-SNVGR--QDSGQYICNATSALGFS---EAYVQLEVDSPPYATVLTEVVVLRVGDALRL 313 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 +CL GS W + G + G G L I + +D+G Y+C A N G Sbjct: 314 QCL-AHGSHPIRFRWMRVGGACMSTG---AESTKDGLLRIPQLKSSDSGTYKCTATNHVG 369 Query: 188 TRES 191 + E+ Sbjct: 370 SSEA 373 Score = 45.2 bits (102), Expect = 0.011 Identities = 53/237 (22%), Positives = 88/237 (37%), Gaps = 19/237 (8%) Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMF-WSVEGNRTIIFPGMSRDKYHATAVFD 351 PS+++ P + V G F C T +P M W N+ + D D Sbjct: 22 PSVSVRPRTAAVRLGETVSFQCRVTSGAQPVMLEWRKINNQPL------GDNVKIGP--D 73 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411 G VLTI + N+ + C A N G S V L+V PP + + TL + Sbjct: 74 GA-VLTIANVRLNN-QGGYRCIATNAQGKSTVTANLSVK----HPPKVRVSPAGPLTLRV 127 Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT--LVLKDLDKSDSGTYTCVA 469 + C+ P P ++W +A + + T D T L + ++G Y C A Sbjct: 128 GEIVTLDCSVSGKPRPSVSW-IRRQAGGETELVSTTTDSTTSLQVTMATAENAGMYVCRA 186 Query: 470 SSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQ 526 + G L+++ P +++++ G + LSWS+ Sbjct: 187 QNGEGLAEGEVELVMEGGAFPQAS-VSETELTAVEGQSVSMHCQASGSPAAVLSWSK 242 >UniRef50_UPI0000E472F4 Cluster: PREDICTED: similar to SEC14 and spectrin domains 1; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to SEC14 and spectrin domains 1 - Strongylocentrotus purpuratus Length = 3464 Score = 107 bits (256), Expect = 2e-21 Identities = 136/551 (24%), Positives = 214/551 (38%), Gaps = 67/551 (12%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68 G APY + D V + + L+C G P+P + W+K GV V + + + Sbjct: 2418 GYAPYFTRKIRDNLVKQGRATQLDCVVKGDPAPEVEWFKDGVPVRTSNNLRVECGDAGIC 2477 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE--------------- 113 + + AGVY +A N G A + A LHV ++EEF L Sbjct: 2478 ALSFYNTQPEAAGVYSIKAFNVIGEAVCK-AELHVQAVQEEFVLPKEVPKVSTGHIKLTH 2536 Query: 114 ----------PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG 163 P K +G ++LE + P+PNV W K+G + G+ + VD Sbjct: 2537 NATMPKFIEIPGDKNVEEGKPLILE-VTVDAYPQPNVVWSKDG--IKVKGEPYILKVDKK 2593 Query: 164 N--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK---PYLITGPEDVVAQTGSS 218 L+I +A D G + C A N AG R I +K++ P +T + A+ G+ Sbjct: 2594 THTLIIPEADLEDEGIFICTATNPAG-RAECIIQVKVNEAEEPPVFLTPLVNAQAKKGTP 2652 Query: 219 VTFQCRVGGDPLPDVLWRRS---AGGGNMPLGRVKVLDDGSLRL--DNVILADEGEYSCE 273 F+C + GDP+P V W ++ N + + G RL D V D YSC Sbjct: 2653 FAFECVLKGDPVPVVEWLKNNKPVKEENPDYNLKRNTETGVCRLEIDEVFPEDAARYSCR 2712 Query: 274 AENSVGAVSASGYLTVYD-------PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326 A N G + L+V P I P + ++ G+ R TC G ++ W Sbjct: 2713 ATNEAGKAETTCMLSVMGLDDDDLRAPVIISHPEDMTLQEGDPIRLTCQIGGELPLSVNW 2772 Query: 327 SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386 E + + G + +G+ VL +N++ D C A N G + Sbjct: 2773 FKE-DEALDEAGEFLMTFDDQ---EGLAVLKVNESFAEDE-GVYTCQATNAWGRTASSAN 2827 Query: 387 L-TVTSDDDRPPPIITNGPSNQTLPIKSMAV-------FPCTAICTPE---PIIAWYFEG 435 L VT+ D+ P ++ I S P C + PI A +++G Sbjct: 2828 LIVVTAVDEIDAAAADVSPKHEAACILSKLENVTVQEGAPFKLACVVDGIAPITAQWYKG 2887 Query: 436 EALIQNHRRNV----TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPN 491 E + V +N TL + + DSG YTC ++ G S + V +P Sbjct: 2888 EEALDEGYEYVMKFQSNMATLHVNESFPEDSGMYTCRVTNAIGSDESSAQVTVLEDSSPT 2947 Query: 492 IHFFRAADVSS 502 + + + S Sbjct: 2948 APWIQPLKLES 2958 Score = 99 bits (238), Expect = 4e-19 Identities = 120/502 (23%), Positives = 187/502 (37%), Gaps = 50/502 (9%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P IE P D V +P L P P + W K G+ V + + IL Sbjct: 2541 PKFIEIPGDKNVEEGKPLILEVTVDAYPQPNVVWSKDGIKVKGEPY--ILKVDKKTHTLI 2598 Query: 72 THGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130 D G++ C ATN G A ++ A F + Q+ +G EC+ Sbjct: 2599 IPEADLEDEGIFICTATNPAGRAECIIQVKVNEAEEPPVFLTPLVNAQAKKGTPFAFECV 2658 Query: 131 PPRGSPEPNVYWKKNGQTLLF---DGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAA 186 +G P P V W KN + + D + + + G L I + DA RY C A N A Sbjct: 2659 L-KGDPVPVVEWLKNNKPVKEENPDYNLKRNTETGVCRLEIDEVFPEDAARYSCRATNEA 2717 Query: 187 GTRESAIATLKIHIK------PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 G E+ + + P +I+ PED+ Q G + C++GG+ V W + Sbjct: 2718 GKAETTCMLSVMGLDDDDLRAPVIISHPEDMTLQEGDPIRLTCQIGGELPLSVNWFKEDE 2777 Query: 241 GGNMPLGRVKVLDD----GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV------Y 290 + + DD L+++ DEG Y+C+A N+ G ++S L V Sbjct: 2778 ALDEAGEFLMTFDDQEGLAVLKVNESFAEDEGVYTCQATNAWGRTASSANLIVVTAVDEI 2837 Query: 291 DPPSINLSP-----------NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGM 339 D + ++SP +V V+ G + C G T W +G + Sbjct: 2838 DAAAADVSPKHEAACILSKLENVTVQEGAPFKLACVVDGIAPITAQW-YKGEEAL----- 2891 Query: 340 SRDKYHATAVF-DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398 + Y F + L +N++ DS C N GS ++TV D P Sbjct: 2892 -DEGYEYVMKFQSNMATLHVNESFPEDS-GMYTCRVTNAIGSDESSAQVTVLEDSSPTAP 2949 Query: 399 II--TNGPSNQ-TLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLK 455 I SN + + PEP + W+ + L + R V + T Sbjct: 2950 WIQPLKLESNSLEITVGQPIKLAFKVSGNPEPTVTWHHDDRPLRPDGRIKVVKEDTTYTM 3009 Query: 456 DLDKS---DSGTYTCVASSRHG 474 + +S D+G YT A + G Sbjct: 3010 QISRSEPDDTGKYTIRAENESG 3031 Score = 65.3 bits (152), Expect = 1e-08 Identities = 74/304 (24%), Positives = 124/304 (40%), Gaps = 35/304 (11%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGLFF 68 AP II P D+T+ P L C+ GG ++ W+K + + + GL Sbjct: 2738 APVIISHPEDMTLQEGDPIRLTCQIGGELPLSVNWFKEDEALDEAGEFLMTFDDQEGLAV 2797 Query: 69 LRATHGRVHSDAGVYWCEATNSYG-TARSRNATLHVAVLREEFR---LEPESKQSA---- 120 L+ D GVY C+ATN++G TA S N + AV + + P+ + + Sbjct: 2798 LKVNESFAE-DEGVYTCQATNAWGRTASSANLIVVTAVDEIDAAAADVSPKHEAACILSK 2856 Query: 121 -------QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDAR 171 +G L C+ +P ++K G+ L +G + L + ++ Sbjct: 2857 LENVTVQEGAPFKLACVVDGIAPITAQWYK--GEEALDEGYEYVMKFQSNMATLHVNESF 2914 Query: 172 QTDAGRYQCIARNAAGTRESAIATLKIH--------IKPYLITGPEDVVAQTGSSVTFQC 223 D+G Y C NA G+ ES+ + I+P + + G + Sbjct: 2915 PEDSGMYTCRVTNAIGSDESSAQVTVLEDSSPTAPWIQPLKLES-NSLEITVGQPIKLAF 2973 Query: 224 RVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGA 280 +V G+P P V W P GR+KV+ + + +++ D G+Y+ AEN G Sbjct: 2974 KVSGNPEPTVTWHHD-DRPLRPDGRIKVVKEDTTYTMQISRSEPDDTGKYTIRAENESGH 3032 Query: 281 VSAS 284 S+S Sbjct: 3033 ESSS 3036 Score = 64.5 bits (150), Expect = 2e-08 Identities = 81/359 (22%), Positives = 126/359 (35%), Gaps = 40/359 (11%) Query: 6 VTSGEAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64 V E P + PL + + P C G P P + W K V + L Sbjct: 2629 VNEAEEPPVFLTPLVNAQAKKGTPFAFECVLKGDPVPVVEWLKNNKPVKEENPDYNLKRN 2688 Query: 65 ---GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL-----EPES 116 G+ L DA Y C ATN G A + + + ++ R PE Sbjct: 2689 TETGVCRLEIDE-VFPEDAARYSCRATNEAGKAETTCMLSVMGLDDDDLRAPVIISHPED 2747 Query: 117 KQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT--- 173 +GD + L C G +V W K + L G+ M D L + ++ Sbjct: 2748 MTLQEGDPIRLTC-QIGGELPLSVNWFKEDEALDEAGEFLMTFDDQEGLAVLKVNESFAE 2806 Query: 174 DAGRYQCIARNAAGTRESAIATLKI----------------HIKPYLITGPEDVVAQTGS 217 D G Y C A NA G S+ + + H +++ E+V Q G+ Sbjct: 2807 DEGVYTCQATNAWGRTASSANLIVVTAVDEIDAAAADVSPKHEAACILSKLENVTVQEGA 2866 Query: 218 SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD--GSLRLDNVILADEGEYSCEAE 275 C V G W + + V +L ++ D G Y+C Sbjct: 2867 PFKLACVVDGIAPITAQWYKGEEALDEGYEYVMKFQSNMATLHVNESFPEDSGMYTCRVT 2926 Query: 276 NSVGAVSASGYLTVYDPPS--------INLSPNSVNVESGNVARFTCTATGRPEPTMFW 326 N++G+ +S +TV + S + L NS+ + G + +G PEPT+ W Sbjct: 2927 NAIGSDESSAQVTVLEDSSPTAPWIQPLKLESNSLEITVGQPIKLAFKVSGNPEPTVTW 2985 Score = 54.0 bits (124), Expect = 2e-05 Identities = 52/179 (29%), Positives = 74/179 (41%), Gaps = 17/179 (9%) Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDG-----DSRMHLVDGGN---LVIQDARQTDA 175 TVV E RG+ N+ +G F+ R+ V G+ LVI+ DA Sbjct: 3287 TVVAE--NERGTETVNIVINVSGVQWFFNNTPIQPSDRVEFVRDGDVYYLVIKRPTSGDA 3344 Query: 176 GRYQCIARNAAGTRESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233 G YQC A + T+ ++ K P I E VVA GS++ +CR+ G P P V Sbjct: 3345 GLYQCRAETEVSVVTTE-CTIMVNDKQSPDFIAPLESVVASEGSTIRLECRMSGSPAPTV 3403 Query: 234 LWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 W + RV+ L +G L + V +D G Y N G +S L + Sbjct: 3404 KWTKDE-RSITETSRVRFLTEGDRQILMIIQVRPSDAGNYRITLTNDFGVSVSSATLLI 3461 Score = 53.6 bits (123), Expect = 3e-05 Identities = 52/202 (25%), Positives = 82/202 (40%), Gaps = 16/202 (7%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 EA I+ + +VTV P L C G +WYKG + + + ++ Sbjct: 2849 EAACILSKLENVTVQEGAPFKLACVVDGIAPITAQWYKGEE-ALDEGYEYVMKFQSNMAT 2907 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE---------FRLEPESKQSA 120 + D+G+Y C TN+ G S ++ V VL + +LE S + Sbjct: 2908 LHVNESFPEDSGMYTCRVTNAIG---SDESSAQVTVLEDSSPTAPWIQPLKLESNSLEIT 2964 Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQ 179 G + L G+PEP V W + + L DG ++ D + I + D G+Y Sbjct: 2965 VGQPIKL-AFKVSGNPEPTVTWHHDDRPLRPDGRIKVVKEDTTYTMQISRSEPDDTGKYT 3023 Query: 180 CIARNAAGTRESAIATLKIHIK 201 A N +G ES+ K+ IK Sbjct: 3024 IRAENESG-HESSSTDYKLVIK 3044 Score = 46.8 bits (106), Expect = 0.004 Identities = 45/176 (25%), Positives = 72/176 (40%), Gaps = 8/176 (4%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 D+ V+ +P + R G P+P I WYK + + + L + D Sbjct: 3122 DIEVSEGEPIEIAIRVTGQPAPRITWYKDDEPINGKPQYEMSFVESVARLDVREAFL-ED 3180 Query: 80 AGVYWCEATNSYG-TARSRNATLHV-AVLREEFRLEPESKQSAQGDTVVLECL----PPR 133 G Y C+ATN G + T++V A L + P Q + D V + + R Sbjct: 3181 EGRYVCKATNPAGQDTTTCQITVNVNAALTPAPHVVPLQTQFSHLDIPVGQPIRLHFRIR 3240 Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGT 188 G P P V W +N ++ + + + LVI++ R G+Y +A N GT Sbjct: 3241 GQPPPKVTWLQNDVEIVETEEVEIIKEETVHTLVIKNPRPDAGGKYTVVAENERGT 3296 Score = 42.7 bits (96), Expect = 0.059 Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 5/88 (5%) Query: 245 PLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN-LSP- 299 P RV+ + DG L + D G Y C AE V V+ + V D S + ++P Sbjct: 3319 PSDRVEFVRDGDVYYLVIKRPTSGDAGLYQCRAETEVSVVTTECTIMVNDKQSPDFIAPL 3378 Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWS 327 SV G+ R C +G P PT+ W+ Sbjct: 3379 ESVVASEGSTIRLECRMSGSPAPTVKWT 3406 Score = 41.5 bits (93), Expect = 0.14 Identities = 34/150 (22%), Positives = 58/150 (38%), Gaps = 11/150 (7%) Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247 T+ A+ + + P + +D+ G + RV G P P + W + N Sbjct: 3100 TQPDAMPVMGAAMPPRFQSRLKDIEVSEGEPIEIAIRVTGQPAPRITWYKDDEPINGKPQ 3159 Query: 248 RVKVLDDGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305 + RLD L DEG Y C+A N G + + +TV ++ +P+ V ++ Sbjct: 3160 YEMSFVESVARLDVREAFLEDEGRYVCKATNPAGQDTTTCQITVNVNAALTPAPHVVPLQ 3219 Query: 306 S---------GNVARFTCTATGRPEPTMFW 326 + G R G+P P + W Sbjct: 3220 TQFSHLDIPVGQPIRLHFRIRGQPPPKVTW 3249 Score = 41.1 bits (92), Expect = 0.18 Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 2/96 (2%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 V ++P I V + L CR GSP+P ++W K + + L G Sbjct: 3366 VNDKQSPDFIAPLESVVASEGSTIRLECRMSGSPAPTVKWTKDERSITETSRVRFLTEGD 3425 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATL 101 L R SDAG Y TN +G + S +ATL Sbjct: 3426 RQILMIIQVR-PSDAGNYRITLTNDFGVSVS-SATL 3459 Score = 37.9 bits (84), Expect = 1.7 Identities = 41/191 (21%), Positives = 67/191 (35%), Gaps = 16/191 (8%) Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 PP + V G TG+P P + W + P + +Y + V + Sbjct: 3113 PPRFQSRLKDIEVSEGEPIEIAIRVTGQPAPRITWYKDDE-----PINGKPQYEMSFV-E 3166 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP-----PIITNGPSN 406 V L + + D VC A N AG ++TV + P P+ T S+ Sbjct: 3167 SVARLDVREAFLEDE-GRYVCKATNPAGQDTTTCQITVNVNAALTPAPHVVPLQTQF-SH 3224 Query: 407 QTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSG 463 +P+ P P + W +++ + + T LV+K+ G Sbjct: 3225 LDIPVGQPIRLHFRIRGQPPPKVTWLQNDVEIVETEEVEIIKEETVHTLVIKNPRPDAGG 3284 Query: 464 TYTCVASSRHG 474 YT VA + G Sbjct: 3285 KYTVVAENERG 3295 >UniRef50_UPI00004D1686 Cluster: Neogenin precursor.; n=1; Xenopus tropicalis|Rep: Neogenin precursor. - Xenopus tropicalis Length = 918 Score = 107 bits (256), Expect = 2e-21 Identities = 78/224 (34%), Positives = 111/224 (49%), Gaps = 23/224 (10%) Query: 29 ATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGLFFLRATHGRVHS-DAGVYWC 85 A LNC A P+P I W K G + VSD R +LP G L H + + D G+Y C Sbjct: 2 AVLNCSAYADPTPKIEWKKDGTFLNLVSDDRRRLLPDGSLLITSVVHSKHNKPDEGIYQC 61 Query: 86 EAT-NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE--PNVYW 142 AT S G+ SR A L VA L F +PES GD++VL C SPE P V+W Sbjct: 62 VATVESLGSIVSRTARLSVAGL-PRFTSQPESSSVYVGDSIVLNC---DVSPELVPFVHW 117 Query: 143 KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI-HIK 201 ++N + + D+R+ ++ G+LVI +A ++DAG Y+C + + S A +++ K Sbjct: 118 EQNKASR--ELDNRVAVLLNGSLVISNANESDAGLYRCAVGGGSSIKYSEEAEIRVLQGK 175 Query: 202 PYLITG----------PEDVVAQTGSSVTFQCRVGGDPLPDVLW 235 +L TG P + +G + C V G P P V W Sbjct: 176 FFLDTGDERPMLFLRQPLPLTRVSGQTALLTCVVSGYPTPSVRW 219 Score = 93.5 bits (222), Expect = 3e-17 Identities = 122/580 (21%), Positives = 224/580 (38%), Gaps = 56/580 (9%) Query: 218 SVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNVILA-----DEGEYS 271 + C DP P + W++ N+ R ++L DGSL + +V+ + DEG Y Sbjct: 1 AAVLNCSAYADPTPKIEWKKDGTFLNLVSDDRRRLLPDGSLLITSVVHSKHNKPDEGIYQ 60 Query: 272 CEAE-NSVGA-VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVE 329 C A S+G+ VS + L+V P P S +V G+ C + P + W E Sbjct: 61 CVATVESLGSIVSRTARLSVAGLPRFTSQPESSSVYVGDSIVLNCDVSPELVPFVHW--E 118 Query: 330 GNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC-SAVNYAGSSFVR---G 385 N+ D A + + + N++D R + S++ Y+ + +R G Sbjct: 119 QNKA----SRELDNRVAVLLNGSLVISNANESDAGLYRCAVGGGSSIKYSEEAEIRVLQG 174 Query: 386 KLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN 445 K + + D+RP + P T A+ C P P + W + ++ R Sbjct: 175 KFFLDTGDERPM-LFLRQPLPLTRVSGQTALLTCVVSGYPTPSVRWTHNQKEILTEKRTM 233 Query: 446 VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPG 505 +L + + G C G + SP P++ A +V++ PG Sbjct: 234 TCRCLVWLLGNSGLPEVGQQ-C-----------QGVTIPTSP-TPSLTRATAHNVAATPG 280 Query: 506 PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565 P N T T + + ++L + + + + + P+ R +V A Sbjct: 281 GPLPSSPRNSTCTCTGKQKKKKKSRLAVNMLRLALALANPDQTKQSVKPQ--RSVLVSAV 338 Query: 566 RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV------------TVGDDSNS 613 + + S P T+ E S P + ++ V + N Sbjct: 339 LASRVAFAGNSSAPAYTFSNNNPMERVENTSRPGEMQVTIQNLLPETVYYFRVVAQNQNG 398 Query: 614 LWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWE--ILNFYYLEGLFIYF--R 669 E + + E + + +ATP+ ++ + WE + ++ +Y+ + Sbjct: 399 AGESS-LPLKVETQPEVQVPGPAPNFKATPVSPTSVSVSWETPLSGNGEIQSYKLYYMEK 457 Query: 670 PLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDD 729 DN + + K V ++ L+KYT+Y F ++ F K G + +TL D Sbjct: 458 GADNEQVRWRFK-----EGVVILKVNGLKKYTEYTFRVVAFNKHGPGVSTQDVTVRTLSD 512 Query: 730 VPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNV 769 VP P N+ + + ++ ++ ++W PP + QNG I GY V Sbjct: 513 VPSAAPQNLTLEVRSSQSILVQWQPPPIGSQNGQIVGYKV 552 Score = 79.0 bits (186), Expect = 7e-13 Identities = 63/220 (28%), Positives = 92/220 (41%), Gaps = 20/220 (9%) Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA-----RQTDAGRYQC 180 VL C P P + WKK+G L D R L+ G+L+I + D G YQC Sbjct: 3 VLNC-SAYADPTPKIEWKKDGTFLNLVSDDRRRLLPDGSLLITSVVHSKHNKPDEGIYQC 61 Query: 181 IAR-NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239 +A + G+ S A L + P + PE G S+ C V + +P V W ++ Sbjct: 62 VATVESLGSIVSRTARLSVAGLPRFTSQPESSSVYVGDSIVLNCDVSPELVPFVHWEQNK 121 Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSC----------EAENSVGAVSASGYLTV 289 + RV VL +GSL + N +D G Y C E + + +L Sbjct: 122 ASRELD-NRVAVLLNGSLVISNANESDAGLYRCAVGGGSSIKYSEEAEIRVLQGKFFLDT 180 Query: 290 YDP-PSINL-SPNSVNVESGNVARFTCTATGRPEPTMFWS 327 D P + L P + SG A TC +G P P++ W+ Sbjct: 181 GDERPMLFLRQPLPLTRVSGQTALLTCVVSGYPTPSVRWT 220 Score = 35.9 bits (79), Expect = 6.7 Identities = 37/149 (24%), Positives = 52/149 (34%), Gaps = 15/149 (10%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P QP +V LNC P + W + D ++L G L A Sbjct: 84 PRFTSQPESSSVYVGDSIVLNCDVSPELVPFVHWEQNKASRELDNRVAVLLNGSLVISNA 143 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR------EE----FRLEPESKQSAQ 121 SDAG+Y C S A + V + +E F +P Sbjct: 144 N----ESDAGLYRCAVGGGSSIKYSEEAEIRVLQGKFFLDTGDERPMLFLRQPLPLTRVS 199 Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLL 150 G T +L C+ G P P+V W N + +L Sbjct: 200 GQTALLTCV-VSGYPTPSVRWTHNQKEIL 227 Score = 35.5 bits (78), Expect = 8.9 Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 1/40 (2%) Query: 7 TSGEAPYI-IEQPLDVTVARHQPATLNCRAGGSPSPAIRW 45 T E P + + QPL +T Q A L C G P+P++RW Sbjct: 180 TGDERPMLFLRQPLPLTRVSGQTALLTCVVSGYPTPSVRW 219 >UniRef50_Q4RKK6 Cluster: Chromosome 5 SCAF15028, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 5 SCAF15028, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 875 Score = 107 bits (256), Expect = 2e-21 Identities = 90/283 (31%), Positives = 124/283 (43%), Gaps = 22/283 (7%) Query: 17 QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI-LPAGGLFFLRATHGR 75 +P T+ A C+ G P+P I W K V V +T I LP GGL L T Sbjct: 7 EPSPQTIPLGGAARFECQIEGVPTPTIMWEKDRVAVPEETSSFISLPNGGLQILGVTK-- 64 Query: 76 VHSDAGVYWCEATNSYGTARSRNATLHVAVLREE------FRLEPESKQSAQGDTVVLEC 129 D G Y +NS T SR A V E + P + G V+EC Sbjct: 65 --KDEGAYRFVLSNSASTDVSREARRTVTTDPTENLNRIVIVVPPRNTTVMLGRLAVMEC 122 Query: 130 LPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188 + G P+P V W +++G+ + D +V NLVI+D R AG Y C A N T Sbjct: 123 MA-EGRPKPLVSWSRQDGKPISTDV-----VVLATNLVIRDTRSHHAGVYVCRA-NKPRT 175 Query: 189 RESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 RE A ++H+ P +I PE G++ F C G+P P + W ++ G Sbjct: 176 REFVTAAAELHVPAPPVIIQPPETASLSRGNTARFVCNSTGEPSPVLHWLKN-GQPVKSF 234 Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 RVK G L ++ + D G Y C A+N +G A+ LTV Sbjct: 235 RRVKSQSPGVLLINQLAPEDAGYYQCIADNGLGTACATAKLTV 277 Score = 95.9 bits (228), Expect = 6e-18 Identities = 101/410 (24%), Positives = 154/410 (37%), Gaps = 31/410 (7%) Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267 P G + F+C++ G P P ++W + L +G L++ V DE Sbjct: 8 PSPQTIPLGGAARFECQIEGVPTPTIMWEKDRVAVPEETSSFISLPNGGLQILGVTKKDE 67 Query: 268 GEYSCEAENSVGA-VSASGYLTVYDPPSINLS-------PNSVNVESGNVARFTCTATGR 319 G Y NS VS TV P+ NL+ P + V G +A C A GR Sbjct: 68 GAYRFVLSNSASTDVSREARRTVTTDPTENLNRIVIVVPPRNTTVMLGRLAVMECMAEGR 127 Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379 P+P + WS + + I +T V T L I DT ++ VC A Sbjct: 128 PKPLVSWSRQDGKPI-----------STDVVVLATNLVIRDT-RSHHAGVYVCRANKPRT 175 Query: 380 SSFVRGKLTVTSDDDRP-PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438 FV T ++ P PP+I P +L + A F C + P P++ W G+ + Sbjct: 176 REFV----TAAAELHVPAPPVIIQPPETASLSRGNTARFVCNSTGEPSPVLHWLKNGQPV 231 Query: 439 IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL--LVDSPINPNIHFFR 496 R + G L++ L D+G Y C+A + G + L +V + H Sbjct: 232 KSFRRVKSQSPGVLLINQLAPEDAGYYQCIADNGLGTACATAKLTVIVREGLPSAPHHLT 291 Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETL---SGNNT 553 A SS T + +D + S G ++ + F ++ Sbjct: 292 ATPYSSTSALLTWEKPEHNSDQIIGYSVHCQRATGLFLVMCLWMSRFLQQAYFFWIFPTF 351 Query: 554 PRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS-PVS 602 P + A T Y++K L P Y F V + G S PS PV+ Sbjct: 352 PGSDNVEYQFAMNNDTTEYLIKELAPYTAYTFFVVAYSPMGASRPSVPVT 401 Score = 90.6 bits (215), Expect = 2e-16 Identities = 124/525 (23%), Positives = 209/525 (39%), Gaps = 44/525 (8%) Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358 P+ + G ARF C G P PT+ W E +R + S + G+ +L + Sbjct: 8 PSPQTIPLGGAARFECQIEGVPTPTIMW--EKDRVAVPEETSS---FISLPNGGLQILGV 62 Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418 D+ R + SA S R +T ++ +I P N T+ + +AV Sbjct: 63 TKKDEGAYRFVLSNSASTDV-SREARRTVTTDPTENLNRIVIVVPPRNTTVMLGRLAVME 121 Query: 419 CTAICTPEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477 C A P+P+++W + G+ + + TN LV++D +G Y C A+ + Sbjct: 122 CMAEGRPKPLVSWSRQDGKPISTDVVVLATN---LVIRDTRSHHAGVYVCRANKPRTREF 178 Query: 478 WSGALLVDSPINPNIHFFRAADVSSLP-GPPTKPITHNVTDTSVTLSWSQNNKIGSSSIL 536 + A + P P I + + +SL G + + ++ + S L W +N + S Sbjct: 179 VTAAAELHVPAPPVI--IQPPETASLSRGNTARFVCNSTGEPSPVLHWLKNGQPVKSF-- 234 Query: 537 GYQVEVFSRETLSGNN-TPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGL 595 +V+ S L N P ++ + IA T L IVR GL Sbjct: 235 -RRVKSQSPGVLLINQLAPEDAGYYQCIADNGLGTACATAKLT------VIVR----EGL 283 Query: 596 -SGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWE 654 S P ++ + + WE E+ ++ + + V AT + M Sbjct: 284 PSAPHHLTATPYSSTSALLTWE------KPEHNSDQIIGYSVHCQRATGLFLVMCLWMSR 337 Query: 655 ILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKF 714 L Y +F F DN+ ++ M +ND + + I L YT Y FF++ + Sbjct: 338 FLQQAYFFWIFPTFPGSDNVEYQFAM-----NNDTTEYLIKELAPYTAYTFFVVAYSPMG 392 Query: 715 EGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWL 774 +PS + ++DVP PP + + + T + L W P + G +T Y + + L Sbjct: 393 ASRPSVPVTVEMMEDVPSSPP-QLAIASTSPTEIRLTWHPLPSERSRGTVTHYRIEYSTL 451 Query: 775 DVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819 V + V + V Q T + L Y V+I+A T IG G Sbjct: 452 -VQDSVFSVEVRGNVTQFT---LRELEPNQVYRVRISAATGIGFG 492 Score = 70.5 bits (165), Expect = 3e-10 Identities = 67/211 (31%), Positives = 93/211 (44%), Gaps = 18/211 (8%) Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73 I+ P + TV + A + C A G P P + W + +S T +L +R T Sbjct: 103 IVVPPRNTTVMLGRLAVMECMAEGRPKPLVSWSRQDGKPIS-TDVVVLATN--LVIRDT- 158 Query: 74 GRVHSDAGVYWCEA----TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 R H AGVY C A T + TA A LHV + PE+ ++G+T C Sbjct: 159 -RSH-HAGVYVCRANKPRTREFVTAA---AELHVPAPPVIIQ-PPETASLSRGNTARFVC 212 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189 G P P ++W KNGQ + R+ G L+I DAG YQCIA N GT Sbjct: 213 -NSTGEPSPVLHWLKNGQPV--KSFRRVKSQSPGVLLINQLAPEDAGYYQCIADNGLGT- 268 Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVT 220 A A L + ++ L + P + A SS + Sbjct: 269 ACATAKLTVIVREGLPSAPHHLTATPYSSTS 299 Score = 54.8 bits (126), Expect = 1e-05 Identities = 37/129 (28%), Positives = 67/129 (51%), Gaps = 3/129 (2%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753 + L+ +T+YE + G S++ TL D P PP +++ L++++V + W Sbjct: 712 LEGLKPFTRYELAVQSNGADVAGPFSDTVEESTLPDRPSTPPEELQLNPLDSSSVLVSWR 771 Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAE 813 PP L+ NGIITGY ++ + ++ + + TS+ + L+SG Y ++ A Sbjct: 772 PP-LE-PNGIITGYFILYSG-NLSQPDDLWEKLSQDGSITSVEVQGLSSGTHYFFKLGAA 828 Query: 814 TIIGLGPFS 822 T +G GP+S Sbjct: 829 TEVGPGPYS 837 Score = 44.8 bits (101), Expect = 0.015 Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 4/83 (4%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P II+ P +++R A C + G PSP + W K G V S R + G+ + Sbjct: 191 PVIIQPPETASLSRGNTARFVCNSTGEPSPVLHWLKNGQPVKS-FRRVKSQSPGVLLINQ 249 Query: 72 THGRVHSDAGVYWCEATNSYGTA 94 DAG Y C A N GTA Sbjct: 250 L---APEDAGYYQCIADNGLGTA 269 >UniRef50_Q7Q0S6 Cluster: ENSANGP00000006166; n=5; cellular organisms|Rep: ENSANGP00000006166 - Anopheles gambiae str. PEST Length = 1286 Score = 107 bits (256), Expect = 2e-21 Identities = 129/492 (26%), Positives = 191/492 (38%), Gaps = 69/492 (14%) Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74 E PL +V R Q A L C P P ++W + G + S +I H Sbjct: 232 ENPL--SVERDQTAKLECNIDAKPKPEQVKWTRNGRFISSHPTHTI------------HR 277 Query: 75 RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRG 134 DAG Y C A N + TL+V + ++E ++K + + +TV ++C Sbjct: 278 VSLQDAGRYTCSADNGLDKIGEQEITLNV-LYPPIVQIETKAKTAEEKETVHIKCNVTAN 336 Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN-----AAGTR 189 P + W K G D D R + G LV++D R DAG Y C N T Sbjct: 337 PPPVTIEWLKEG-----DIDFRRN---GDTLVLRDVRAEDAGTYICRGINMMKPYGGKTL 388 Query: 190 E----SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVG--GDPLPDVLWRRSAGGGN 243 E +++A L H + PE V G+SV+ C+ G P P W R GG Sbjct: 389 EREGNASVALLVRHRPGQAVITPEKPVVHVGNSVSLMCKADPPGYPDPQYRWYRDVGG-- 446 Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSPNSV 302 + + + L+ EG+Y C A N +G AS L ++ PP S Sbjct: 447 -EVSTTVIAQGAQYLIPKAALSSEGKYHCHASNELGNGGMASATLEIHQPPQFLAKLQSN 505 Query: 303 NVESGNVARF--TCTATGRPEPTMFW-------SVEGNRTIIFPGMSRDKYHATAV---- 349 ++ A F TC+A G+PEP++ W + E +R + + + V Sbjct: 506 MIKRAGEADFFVTCSAKGKPEPSITWLKDDVEITPELHRYEVKTNVDKGPNGMVTVQSML 565 Query: 350 -FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408 F G ND D R C N + L + + PI+ + + Sbjct: 566 KFTGKARPNGNDLISTD-RGQYTCLYENEVNKANSTMHLKIEHE-----PIVLHQYNKVA 619 Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ--NHRRNVTN-DG----TLVLK--DLDK 459 IK A C P+P W+F G L+ H +TN DG T +LK ++ Sbjct: 620 NDIKETAEVLCKVQSYPKPEFLWHF-GTTLLSTGGHYEIITNSDGNDVYTSILKISNVRH 678 Query: 460 SDSGTYTCVASS 471 D G Y C S+ Sbjct: 679 QDYGEYHCRVSN 690 Score = 62.1 bits (144), Expect = 9e-08 Identities = 70/308 (22%), Positives = 115/308 (37%), Gaps = 39/308 (12%) Query: 30 TLNCRAG--GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEA 87 +L C+A G P P RWY+ V + +++ G + + S G Y C A Sbjct: 423 SLMCKADPPGYPDPQYRWYRD---VGGEVSTTVIAQGAQYLIPKA---ALSSEGKYHCHA 476 Query: 88 TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147 +N G +ATL + + + G+ +G PEP++ W K+ Sbjct: 477 SNELGNGGMASATLEIHQPPQFLAKLQSNMIKRAGEADFFVTCSAKGKPEPSITWLKDDV 536 Query: 148 TLL-----FDGDSRMHLVDGGNLVIQ--------------DARQTDAGRYQCIARNAAGT 188 + ++ + + G + +Q D TD G+Y C+ N Sbjct: 537 EITPELHRYEVKTNVDKGPNGMVTVQSMLKFTGKARPNGNDLISTDRGQYTCLYENEVNK 596 Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGGGNM 244 S + LKI +P ++ V + C+V P P+ LW + GG+ Sbjct: 597 ANSTMH-LKIEHEPIVLHQYNKVANDIKETAEVLCKVQSYPKPEFLWHFGTTLLSTGGHY 655 Query: 245 PLGRVKVLDD---GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301 + +D L++ NV D GEY C NS+ + L PP PN Sbjct: 656 EIITNSDGNDVYTSILKISNVRHQDYGEYHCRVSNSLNHIQVPIRLQPKGPPE---KPNK 712 Query: 302 VN-VESGN 308 + VE G+ Sbjct: 713 LKAVELGS 720 Score = 61.7 bits (143), Expect = 1e-07 Identities = 103/441 (23%), Positives = 159/441 (36%), Gaps = 54/441 (12%) Query: 12 PYIIEQPLDVTVARHQPATLNCRA-GGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 P +I + T + L C + GGSP P I WY+ G + L GG ++ Sbjct: 124 PPLIFPGSETTATEDKKQELTCSSVGGSPDPTISWYREGSTTPLAAN---LIYGGSRDMQ 180 Query: 71 ATHG-----RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE--PESKQSAQGD 123 T R D + C N R T+ +R R+E PE+ S + D Sbjct: 181 TTSTLTIIPRREDDGAKFTCVVWNRAMPESQRLETVTTLSVRYYPRVEIGPENPLSVERD 240 Query: 124 -TVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181 T LEC + + PE V W +NG+ + +H V +QDA GRY C Sbjct: 241 QTAKLECNIDAKPKPE-QVKWTRNGRFISSHPTHTIHRVS-----LQDA-----GRYTCS 289 Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRRSA- 239 A N TL + P + + A+ +V +C V +P P + W + Sbjct: 290 ADNGLDKIGEQEITLNVLYPPIVQIETKAKTAEEKETVHIKCNVTANPPPVTIEWLKEGD 349 Query: 240 -----GGGNMPLGRVKVLDDGSLRLDNV-ILADEGEYSCEAENSVGAVSASGYLTVYDPP 293 G + L V+ D G+ + ++ G + E E + ++ L + P Sbjct: 350 IDFRRNGDTLVLRDVRAEDAGTYICRGINMMKPYGGKTLEREGN----ASVALLVRHRPG 405 Query: 294 SINLSPNSVNVESGNVARFTCTA--TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 ++P V GN C A G P+P W + + T + Sbjct: 406 QAVITPEKPVVHVGNSVSLMCKADPPGYPDPQYRWYRDVGGEV----------STTVIAQ 455 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411 G L ++ + C A N G+ G + T + +PP + SN Sbjct: 456 GAQYLIPKAALSSEGK--YHCHASNELGNG---GMASATLEIHQPPQFLAKLQSNMIKRA 510 Query: 412 KSMAVF-PCTAICTPEPIIAW 431 F C+A PEP I W Sbjct: 511 GEADFFVTCSAKGKPEPSITW 531 Score = 43.6 bits (98), Expect = 0.034 Identities = 60/224 (26%), Positives = 92/224 (41%), Gaps = 22/224 (9%) Query: 257 LRLDNVILA-DEGEYSCEAEN--SVGAVSASGY-LTVYDPPSINLS-PNSVNVESGNVAR 311 L++ NV A D G + C + S A+ Y LTV PP L P S + + + Sbjct: 82 LQIFNVSYARDNGRFECRIKQIGSDNAIYEDYYNLTVLTPPQPPLIFPGSETTATEDKKQ 141 Query: 312 -FTCTATG-RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369 TC++ G P+PT+ W EG+ T P + Y + + LTI ++D Sbjct: 142 ELTCSSVGGSPDPTISWYREGSTT---PLAANLIYGGSRDMQTTSTLTIIPRREDDGAK- 197 Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ-TLPIKSMAVFPCTAICTPEP- 427 C N A R + TVT+ R P + GP N ++ A C P+P Sbjct: 198 FTCVVWNRAMPESQRLE-TVTTLSVRYYPRVEIGPENPLSVERDQTAKLECNIDAKPKPE 256 Query: 428 IIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471 + W G R +++ T + + D+G YTC A + Sbjct: 257 QVKWTRNG--------RFISSHPTHTIHRVSLQDAGRYTCSADN 292 >UniRef50_P23468 Cluster: Receptor-type tyrosine-protein phosphatase delta precursor; n=183; Eumetazoa|Rep: Receptor-type tyrosine-protein phosphatase delta precursor - Homo sapiens (Human) Length = 1912 Score = 107 bits (256), Expect = 2e-21 Identities = 156/644 (24%), Positives = 245/644 (38%), Gaps = 87/644 (13%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LR 258 P P D +G +F C+ GDP P ++W + + V DDGS LR Sbjct: 24 PRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLR 83 Query: 259 LDNVILA-DEGEYSCEAENSVGAVSASGYLTVYDP-------PSINLSPNSVNVESGNVA 310 + + DE Y C A N+VG +S S LTV P+I++ P VE A Sbjct: 84 IQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTA 143 Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV---LTINDTDKNDSR 367 C A+G P+P + W + R K + G + L I ++++D + Sbjct: 144 TMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESD-Q 202 Query: 368 NTIVCSAVNYAGSSF-VRGKLTVTS--DDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424 C A N AG+ + L V + R PP + P+N + C A+ + Sbjct: 203 GKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGS 262 Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 P P + W E L + G VL+ D S YTCVA S G Sbjct: 263 PMPYVKWMLGAEDLTPEDDMPI---GRNVLELNDVRQSANYTCVAMSTLGV--------- 310 Query: 485 DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFS 544 I V +LP PP P+ T TS+TL+W N + Y ++ Sbjct: 311 -------IEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGN---PEPVSYYIIQ--- 357 Query: 545 RETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS-PVSD 603 + P+NS V T Y V L P Y F V N+ G PS PV Sbjct: 358 -------HKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPV-- 408 Query: 604 SVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILN--FYYL 661 L + + + S+ R+ ++A + S TI + W+ + Sbjct: 409 ----------LTQTSEQAPSSAPRD----------VQARMLSSTTILVQWKEPEEPNGQI 448 Query: 662 EGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNS 721 +G +Y+ + MK + + ++ I +L Y ++ F +G S+ Sbjct: 449 QGYRVYYTMDPTQHVNNWMKHNVADSQIT--TIGNLVPQKTYSVKVLAFTSIGDGPLSSD 506 Query: 722 RVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKS 781 T VP G P+N + + T++ L W+PP ++ I Y +V + D + Sbjct: 507 IQVITQTGVP-GQPLNFKAEPESETSILLSWTPP----RSDTIANYELV--YKDGEHGEE 559 Query: 782 MVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825 T+ TS + L Y ++AA + GLG + ++ Sbjct: 560 Q---RITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEI 600 Score = 97.1 bits (231), Expect = 3e-18 Identities = 94/349 (26%), Positives = 142/349 (40%), Gaps = 46/349 (13%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI-LPAGGLFFLR 70 P P+D T A+ C+A G P P I W K G V + I G LR Sbjct: 24 PRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLR 83 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE--------FRLEPESKQSAQG 122 R D +Y C A+N+ G + + + VLRE+ + P+ K + Sbjct: 84 IQPLRTPRDEAIYECVASNNVGEI---SVSTRLTVLREDQIPRGFPTIDMGPQLKVVERT 140 Query: 123 DTVVLECLPPRGSPEPNVYWKK----------NGQTLLFDGDSRMHLVDGGNLVIQDARQ 172 T + C G+P+P + W K NG+ +S G L I+ + + Sbjct: 141 RTATMLCAAS-GNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEE 199 Query: 173 TDAGRYQCIARNAAGTRESAIATLKI-------HIKPYLITGPEDVVAQTGSSVTFQCRV 225 +D G+Y+C+A N+AGTR SA A L + + P P + G SV C Sbjct: 200 SDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVA 259 Query: 226 GGDPLPDVLWRRSAGG----GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281 G P+P V W A +MP+GR VL+ +R Y+C A +++G + Sbjct: 260 VGSPMPYVKWMLGAEDLTPEDDMPIGR-NVLELNDVR-------QSANYTCVAMSTLGVI 311 Query: 282 SASGYLTVYDPPSINLSPNSVNVESGNVARFTCT-ATGRPEPTMFWSVE 329 A +TV P P + V T T +G PEP ++ ++ Sbjct: 312 EAIAQITVKALPK---PPGTPVVTESTATSITLTWDSGNPEPVSYYIIQ 357 Score = 70.1 bits (164), Expect = 3e-10 Identities = 102/422 (24%), Positives = 171/422 (40%), Gaps = 36/422 (8%) Query: 505 GPPTKPITHNVTDTSVTLSWSQN--NKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562 GPP K V TSV +SW NK I GYQV E P + Sbjct: 713 GPPRKVEVEAVNSTSVKVSWRSPVPNK-QHGQIRGYQVHYVRMENGEPKGQPMLKDVMLA 771 Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSN 622 A+ +I G+ + E S+ L+ V+ T GD + S + + Sbjct: 772 DAQWEFDDTTEHDMIISGL------QPETSYSLT----VTAYTTKGDGARSKPKLVSTTG 821 Query: 623 STEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKT 682 + + ++ +H T +++ I+ + F L+G + F D +E + T Sbjct: 822 AVPGKPRLVINH-------TQMNTALIQWHPPVDTFGPLQGYRLKFGRKD---ME-PLTT 870 Query: 683 ILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFI 742 + S F T + K Y F L K G+ ++ ++VP G P N+ Sbjct: 871 LEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIP-EEVPTGFPQNLHSEG 929 Query: 743 LNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTS 802 +T+V L W PP L +NGIIT Y ++ +++P + V T++ +T L Sbjct: 930 TTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPL---LPMEQLIVPADTTMTLTGLKP 986 Query: 803 GVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETW-F 861 +Y V++ A T G GP+S V F R++ +D + + N V V V+ +W Sbjct: 987 DTTYDVKVRAHTSKGPGPYSPSVQF----RTLPVDQV--FAKNFHVKAVMKTSVLLSWEI 1040 Query: 862 YFLIGAIVLFKIIVIAGIIYVRKYNIFAKKSALPNIYDSNGTSLVTQMNIKAAVSLSHPL 921 + + FKI+ G + V + + A + + N+ S V +A L H + Sbjct: 1041 PENYNSAMPFKILYDDGKM-VEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSAGGLQHRV 1099 Query: 922 TS 923 T+ Sbjct: 1100 TA 1101 Score = 65.7 bits (153), Expect = 7e-09 Identities = 55/198 (27%), Positives = 78/198 (39%), Gaps = 21/198 (10%) Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 PP +P SG VA F C ATG P P + W+ +G + +S ++ D Sbjct: 23 PPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKK------VSNQRFEVIEFDD 76 Query: 352 GV-TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP--PIITNGPSNQT 408 G +VL I C A N G V +LTV +D P P I GP + Sbjct: 77 GSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKV 136 Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFE--------GEALIQNHRRNVTND----GTLVLKD 456 + A C A P+P I W+ + I+ R G L ++ Sbjct: 137 VERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQ 196 Query: 457 LDKSDSGTYTCVASSRHG 474 ++SD G Y CVA++ G Sbjct: 197 SEESDQGKYECVATNSAG 214 Score = 64.5 bits (150), Expect = 2e-08 Identities = 52/210 (24%), Positives = 90/210 (42%), Gaps = 8/210 (3%) Query: 642 TPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYT 701 T + +I L W+ N + I +P ++ + E+ + + + + L Y+ Sbjct: 332 TESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTR----YSVAGLSPYS 387 Query: 702 KYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQN 761 YEF ++ G PS + QT + P P +++ +L++TT+ ++W PE N Sbjct: 388 DYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPE--EPN 445 Query: 762 GIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPF 821 G I GY V + + N Q T++ NL +YSV++ A T IG GP Sbjct: 446 GQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTI--GNLVPQKTYSVKVLAFTSIGDGPL 503 Query: 822 SQKVYFNIDSRSVGLDLLSRYPMNGEVSIV 851 S + + G L + E SI+ Sbjct: 504 SSDIQVITQTGVPGQPLNFKAEPESETSIL 533 Score = 59.7 bits (138), Expect = 5e-07 Identities = 42/171 (24%), Positives = 72/171 (42%), Gaps = 6/171 (3%) Query: 690 SGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVH 749 + + + L+ + Y F L + G + A+T+ P PP +I ++T++ Sbjct: 568 TSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSIL 627 Query: 750 LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQ 809 + W PP ++ QNGIIT Y++ +D +K + T ++ L Y + Sbjct: 628 VSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIP-SDTTKYLLEQLEKWTEYRIT 686 Query: 810 IAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETW 860 + A T +G GP S V + D+ S P EV V V +W Sbjct: 687 VTAHTDVGPGPESLSVLIRTNE-----DVPSGPPRKVEVEAVNSTSVKVSW 732 Score = 54.0 bits (124), Expect = 2e-05 Identities = 27/83 (32%), Positives = 44/83 (53%) Query: 687 NDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTT 746 +D + + + L K+T+Y + G S S + +T +DVP GPP +E+ +N+T Sbjct: 667 SDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNST 726 Query: 747 TVHLKWSPPELQLQNGIITGYNV 769 +V + W P Q+G I GY V Sbjct: 727 SVKVSWRSPVPNKQHGQIRGYQV 749 Score = 38.3 bits (85), Expect = 1.3 Identities = 33/98 (33%), Positives = 44/98 (44%), Gaps = 7/98 (7%) Query: 393 DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT--NDG 450 D PP T P +QT +A F C A P P I W +G+ + N R V +DG Sbjct: 19 DAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKK-VSNQRFEVIEFDDG 77 Query: 451 T---LVLKDL-DKSDSGTYTCVASSRHGKYVWSGALLV 484 + L ++ L D Y CVAS+ G+ S L V Sbjct: 78 SGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTV 115 >UniRef50_UPI0000F2186B Cluster: PREDICTED: hypothetical protein; n=1; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 11202 Score = 106 bits (255), Expect = 3e-21 Identities = 130/517 (25%), Positives = 198/517 (38%), Gaps = 49/517 (9%) Query: 6 VTSGEAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64 +T+ P E L D VA + L C G+P + WYK G + + + G Sbjct: 597 ITTFTEPARFELKLKDKQVAMSKNLKLECTFTGAPKIFVTWYKDGKQLYASYRYNTTVVG 656 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGD 123 L H G Y CE +NSYG T R L +S Q QG Sbjct: 657 NTCTLECLHECTKETPGKYSCEVSNSYGKDICHAEVTTFSGPARFVKTLTDQSLQ--QGQ 714 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTD---AGRYQC 180 + LE +G + V W K+G+ ++ G V++ + D G+Y C Sbjct: 715 KLRLEA-SFKGIGKIFVTWYKDGKQAYASYRCNTKVI-GNTCVLEYLHECDENTPGKYSC 772 Query: 181 IARNAAGTRE-SAIATL--KIHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 N G+ A+ TL + I P P E + G V + RV G V+W Sbjct: 773 EVMNEDGSDICHALVTLGTERKIPPTFTKKPSEHIEDAEGKLVKLESRVSGSQPLSVIWY 832 Query: 237 RSAGGGN-MPLGRVKVLDDGSLR-LDNVILADEGEYSCEAENSVGAVSASGYLTVYD--- 291 + N + V + ++ L + D G Y+C A N G S + + + Sbjct: 833 KDNKEINTSDIYDVSFKSNVAVMCLRKATVTDSGVYTCSASNEAGTASFQVVVNITEQKR 892 Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 PP+ ++ + V G +C G P + W ++ R + ++ + D Sbjct: 893 PPTFDIPLKPMTVSEGERLNLSCHVCGSPPVKIQW-MKDRREVTSSASTKMTF-----VD 946 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN----- 406 G L IN K D+ +C A N AGS F + K+T+ P P+ Sbjct: 947 GTATLEINQASKTDA-GDYLCKATNNAGSEFSKTKVTIKDKAGVAPAAAPAAPTTPQATK 1005 Query: 407 -----------QTLPI--KSMAVFPCTAICTPEPIIAWYFEGEALIQNH--RRNVTNDG- 450 +++ I K A F P P + W +G+ H R N+ G Sbjct: 1006 KLDNLFFIEEPKSIHIVEKGTATFIAKVGGDPIPNVKW-MKGKWRQMTHGGRINIQQKGQ 1064 Query: 451 --TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485 L +K++ KSDSG Y CVAS++HG+ S L VD Sbjct: 1065 ESKLEIKEVTKSDSGQYRCVASNKHGEIECSTDLNVD 1101 Score = 93.5 bits (222), Expect = 3e-17 Identities = 109/545 (20%), Positives = 201/545 (36%), Gaps = 29/545 (5%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 +T+ E + + ++++ Q L C+ G + WYK G + + + Sbjct: 313 ITASEPARFLRKLSNISIPMSQKLRLECKFTGDRKLFVTWYKDGKQLYASYRYNTTVTDN 372 Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125 L + ++ G+Y CE +N++G +AT+ F + + Sbjct: 373 SCTLESLQECDNTTTGIYSCEVSNAFG-REICHATVTAVTEPARFVKKLTDMSIPMSQKL 431 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV--IQDARQTDAGRYQCIAR 183 LEC G+P+ V W K+G+ L + ++ + + GRY C Sbjct: 432 RLEC-TFTGAPKLFVTWYKDGKQLYASYRYNTKVTSNSCILECLHECNNETTGRYSCEVS 490 Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 N GT + + + + DV + +C G P V W + G Sbjct: 491 NIYGTDKCHAQVVAVTEPARFVKKLTDVAIPVTQKLRLECTFTGAPKIFVTWYKD--GKQ 548 Query: 244 MPLG---RVKVLDDGSLR--LDNVILADEGEYSCEAENSVGAVSASGYLTVY-DPPSINL 297 + KV+ D + L A G+YSCE NS+G +T + +P L Sbjct: 549 LYASYRYNTKVIGDTCILECLHECNDATPGKYSCEVSNSIGTDICHANITTFTEPARFEL 608 Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 V + CT TG P+ + W +G + + +Y+ T V + T+ Sbjct: 609 KLKDKQVAMSKNLKLECTFTGAPKIFVTWYKDGKQL-----YASYRYNTTVVGNTCTLEC 663 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417 +++ K ++ C N G ++T S R +T+ Q ++ A F Sbjct: 664 LHECTK-ETPGKYSCEVSNSYGKDICHAEVTTFSGPARFVKTLTDQSLQQGQKLRLEASF 722 Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLK---DLDKSDSGTYTCVASSRH 473 + + WY +G+ ++R N G T VL+ + D++ G Y+C + Sbjct: 723 KGIG----KIFVTWYKDGKQAYASYRCNTKVIGNTCVLEYLHECDENTPGKYSCEVMNED 778 Query: 474 GKYVWSG--ALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK-I 530 G + L + I P + + G K + +++ W ++NK I Sbjct: 779 GSDICHALVTLGTERKIPPTFTKKPSEHIEDAEGKLVKLESRVSGSQPLSVIWYKDNKEI 838 Query: 531 GSSSI 535 +S I Sbjct: 839 NTSDI 843 Score = 83.4 bits (197), Expect = 3e-14 Identities = 113/565 (20%), Positives = 203/565 (35%), Gaps = 29/565 (5%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 E +++ D+++ Q L C G+P + WYK G + + + L Sbjct: 412 EPARFVKKLTDMSIPMSQKLRLECTFTGAPKLFVTWYKDGKQLYASYRYNTKVTSNSCIL 471 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT--VVL 127 H + G Y CE +N YGT + V + E R + A T + L Sbjct: 472 ECLHECNNETTGRYSCEVSNIYGTDKCH---AQVVAVTEPARFVKKLTDVAIPVTQKLRL 528 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV--IQDARQTDAGRYQCIARNA 185 EC G+P+ V W K+G+ L ++ ++ + + G+Y C N+ Sbjct: 529 EC-TFTGAPKIFVTWYKDGKQLYASYRYNTKVIGDTCILECLHECNDATPGKYSCEVSNS 587 Query: 186 AGTRESAIATLKIHIKPYLI-TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--G 242 GT + A + +P +D ++ +C G P V W + Sbjct: 588 IGT-DICHANITTFTEPARFELKLKDKQVAMSKNLKLECTFTGAPKIFVTWYKDGKQLYA 646 Query: 243 NMPLGRVKVLDDGSLR-LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP-N 300 + V + +L L G+YSCE NS G +T + P+ + Sbjct: 647 SYRYNTTVVGNTCTLECLHECTKETPGKYSCEVSNSYGKDICHAEVTTFSGPARFVKTLT 706 Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHA-TAVFDGVTVLT-I 358 +++ G R + G + + W +G + Y T V VL + Sbjct: 707 DQSLQQGQKLRLEASFKGIGKIFVTWYKDGKQAYA-------SYRCNTKVIGNTCVLEYL 759 Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418 ++ D+N + C +N GS +T+ + + PP T PS + V Sbjct: 760 HECDEN-TPGKYSCEVMNEDGSDICHALVTL-GTERKIPPTFTKKPSEHIEDAEGKLVKL 817 Query: 419 CTAICTPEPI-IAWYFEGEALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRHG 474 + + +P+ + WY + + + + +V +N + L+ +DSG YTC AS+ G Sbjct: 818 ESRVSGSQPLSVIWYKDNKEINTSDIYDVSFKSNVAVMCLRKATVTDSGVYTCSASNEAG 877 Query: 475 KYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSS 534 + + + P ++ G H V + W ++ + +SS Sbjct: 878 TASFQVVVNITEQKRPPTFDIPLKPMTVSEGERLNLSCHVCGSPPVKIQWMKDRREVTSS 937 Query: 535 ILGYQVEVFSRETLSGNNTPRNSRG 559 V TL N + G Sbjct: 938 ASTKMTFVDGTATLEINQASKTDAG 962 Score = 79.4 bits (187), Expect = 6e-13 Identities = 105/489 (21%), Positives = 180/489 (36%), Gaps = 31/489 (6%) Query: 2 SDDYVTSGEAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI 60 S + S E P + ++ + ++ P C +P+ +W+K G + I Sbjct: 213 SQGFTRSEEVPPVFKKKICNMESNIGNPVKFECEIEETPNVTFKWFKAGSEIKQSDKVRI 272 Query: 61 LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS- 119 + L D+G Y C A+N +G + + +A L++ L S S Sbjct: 273 ISRQTTSSLELP-SPTKDDSGEYSCRASNKHG-SDTCSAQLNITASEPARFLRKLSNISI 330 Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV--IQDARQTDAGR 177 + LEC G + V W K+G+ L + D + +Q+ T G Sbjct: 331 PMSQKLRLEC-KFTGDRKLFVTWYKDGKQLYASYRYNTTVTDNSCTLESLQECDNTTTGI 389 Query: 178 YQCIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 Y C NA G RE AT+ +P + D+ + +C G P V W Sbjct: 390 YSCEVSNAFG-REICHATVTAVTEPARFVKKLTDMSIPMSQKLRLECTFTGAPKLFVTWY 448 Query: 237 RSAGGGNMPLG---RVKVLDDGSLR--LDNVILADEGEYSCEAENSVGAVSA-SGYLTVY 290 + G + KV + + L G YSCE N G + + V Sbjct: 449 KD--GKQLYASYRYNTKVTSNSCILECLHECNNETTGRYSCEVSNIYGTDKCHAQVVAVT 506 Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350 +P V + R CT TG P+ + W +G + + +Y+ + Sbjct: 507 EPARFVKKLTDVAIPVTQKLRLECTFTGAPKIFVTWYKDGKQL-----YASYRYNTKVIG 561 Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410 D + +++ + + + C N G+ +T ++ P Q Sbjct: 562 DTCILECLHECN-DATPGKYSCEVSNSIGTDICHANITTFTE---PARFELKLKDKQVAM 617 Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTL-VLKDLDKSDSGTYT 466 K++ + CT P+ + WY +G+ L ++R N T N TL L + K G Y+ Sbjct: 618 SKNLKL-ECTFTGAPKIFVTWYKDGKQLYASYRYNTTVVGNTCTLECLHECTKETPGKYS 676 Query: 467 CVASSRHGK 475 C S+ +GK Sbjct: 677 CEVSNSYGK 685 Score = 79.4 bits (187), Expect = 6e-13 Identities = 114/474 (24%), Positives = 174/474 (36%), Gaps = 46/474 (9%) Query: 10 EAPYI-IEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67 E P++ +PL DV V + A C S +RW+K G + I+ A GL Sbjct: 3733 EPPFVEFSKPLHDVEVKEKESAKFECEVSRE-SAKVRWFKDGAEIRKGKKYEII-AKGLQ 3790 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127 + V D Y C+A S + + V+ EE R +T + Sbjct: 3791 RILIISKAVFDDEAEYECDARTSKSSGM-------LTVVEEEARFTKNLANVEGTETDSI 3843 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNA 185 + + P V W K Q + +G H+ DG L+IQD R DAG Y C + Sbjct: 3844 KMVCEVSKPSAEVTWHKGDQEIP-EGGRYEHVADGKKRILIIQDLRMDDAGEYHCKLPAS 3902 Query: 186 AGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 T TLKI + I P++ G F C V D +V W + G + Sbjct: 3903 ETT-----GTLKISELAAEFIARPQNQETVEGEKAEFVCSVSKDNY-EVKWFK--GDKEL 3954 Query: 245 PL-GRVKVLDDGSLR---LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300 + +++ DG R + N L DEG ++ ++G+V AS L V + I Sbjct: 3955 TTDDKYEIVVDGKRRALIIKNCELKDEGAFTA----NIGSVKASANLLVIEKLRIITPLK 4010 Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360 V+ G C W ++ N T M A D V L I Sbjct: 4011 DTQVKEGQEIVLNCEVNSEGAKAK-W-LKNNET-----MFESSKFVMAQRDTVFSLRIKA 4063 Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420 +K+D + + + N G + K + I + + K F C Sbjct: 4064 AEKSDEASYTI-TLTNQRGE---QAKCSANISVHEEALKIIEPLEDCEIEEKKTITFTC- 4118 Query: 421 AICTPEPIIAWYFEGEALIQNHR---RNVTNDGTLVLKDLDKSDSGTYTCVASS 471 + P + W G+ + + R R + TL +KD +D G YT VA + Sbjct: 4119 KVNRPNVTVQWMKAGQEITLSKRILYRVDKDKHTLTIKDCSLADEGEYTVVAGT 4172 Score = 63.7 bits (148), Expect = 3e-08 Identities = 107/456 (23%), Positives = 175/456 (38%), Gaps = 57/456 (12%) Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK--SMAVFPCTAICTPEP 427 I +AVN + S + + V++++ PP I + + LP+K S P P Sbjct: 10361 IAKTAVNISRPSEITDPILVSAENV-PPRIELSVQMKKMLPVKAGSDVCLEAEVFGKPMP 10419 Query: 428 IIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 + W GE L + ++ L LD V G Y G ++ Sbjct: 10420 KVTWSKNGETLKADKEFKMSQKRHLFSLSLD--------AVTKLHAGNY---GIHAANAS 10468 Query: 488 INPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRET 547 N + +PGPP + V LSW G S I Y V+ RET Sbjct: 10469 GNTTAEI--QLKILDIPGPPASVKLDEILSDRVKLSWEAPLVDGGSPITNYVVD--KRET 10524 Query: 548 LSGNNTPRNSRGWVVIARRVHQ--THYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605 W ++ ++ + T V+ LI G Y F VR EN +G +G + +S+ V Sbjct: 10525 SRAE--------WAQVSAKISRDTTECSVERLIEGHEYQFRVRAENHYG-TGDAIISEPV 10575 Query: 606 TVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLF 665 + + + G + NI +H+ + D K+ L G Sbjct: 10576 V----ARNPFTVPGACDPPVL-TNITKEHMTVSWKEPSDDGKSPIL-----------GYL 10619 Query: 666 IYFRPLDNIT-IEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN-SRV 723 + R + + K +L E+ L + +YEF +I K GKPS+ S Sbjct: 10620 VEKRETKEVNWTKINRKPLLERT----LEVGGLSEGAQYEFRVIAVNKAGLGKPSDPSNA 10675 Query: 724 AQTLDDV-PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSM 782 A LD + P GPPI+ + +T+ L W+ P + I+ GY V ++ Sbjct: 10676 ASALDPLYPPGPPISPKAIDTTNSTIKLTWTKPANDGGSDIL-GYLVECKRIN---TTDW 10731 Query: 783 VAINTTVH-QATSLIMTNLTSGVSYSVQIAAETIIG 817 + N + Q T+ ++T L Y ++++A IG Sbjct: 10732 IRCNVPKNLQDTNYVVTGLLENSEYQLRVSAVNKIG 10767 Score = 63.3 bits (147), Expect = 4e-08 Identities = 83/324 (25%), Positives = 136/324 (41%), Gaps = 40/324 (12%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRET---LSGNNTPRNSRGW 560 PG PT+ ++T +VTL+W + ++ G S I GY VE F ET + N P Sbjct: 5245 PGAPTRVQPSDITRDAVTLTWYEPDEDGGSPITGYWVERFDPETDKWIKSNKLP------ 5298 Query: 561 VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGV 620 + T + VK L Y F V EN G PS +D V + D + W Sbjct: 5299 ------IKDTTFRVKGLPTKKKYKFRVLAENLAGQGKPSVETDPVLIKDPIDPPW----- 5347 Query: 621 SNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNI-TIEYE 679 + + +I +L P K+ I+ G + R +++ T E+ Sbjct: 5348 APGKPFVKDIAKTS-ADLQWTRPEHDGGAKIESYIIEL-QKTGTEEWVRVAEDVPTTEHS 5405 Query: 680 MKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIE 739 +K ++ + S F + ++ + E PS+ V + VP+ PP +E Sbjct: 5406 LKGLMEKQEYS-FRVKAINVAGESE----------PSDPSDPVVCKERLYVPN-PPRWLE 5453 Query: 740 MFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTN 799 + + LKW+ P+ IT Y VV DV ++ A++TTV + T +T Sbjct: 5454 VVNITKINCDLKWTEPDSD-GGSPITNY--VVEKRDV-RRRTWQAVDTTV-KDTKYTVTP 5508 Query: 800 LTSGVSYSVQIAAETIIGLGPFSQ 823 L+ G Y ++AAE +G+ F + Sbjct: 5509 LSEGSLYVFRVAAENAVGISEFCE 5532 Score = 58.8 bits (136), Expect = 8e-07 Identities = 75/327 (22%), Positives = 125/327 (38%), Gaps = 36/327 (11%) Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV------FD 351 S +N +G + T +G+P P + W +G P +++ H V D Sbjct: 7183 SQELLNCRAGTTLKIPATISGKPLPNVTWEFDGTA----PSEKKNERHTLPVDSDISSSD 7238 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411 +V+TI ++ + S I+ +A N AG+ V+ ++ V P I + + T + Sbjct: 7239 TTSVVTIPESKLHHSGRYII-TANNQAGTKIVKVRVNVLDLPGAPKDITISDITRGTCRL 7297 Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG----TLVLKDLDKSDSGTYTC 467 C I YF + ++ N +LV+ DL + + Sbjct: 7298 SWKP-----PDCDGGDRIKSYFIEKKTVEGKAWTKVNPACTTQSLVVPDLIEGQEYLFRI 7352 Query: 468 VASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527 A +R G P I +A D P PPT+ +V+ VTL+W Sbjct: 7353 RAENRFGY----------GPHTTTIEGTKARDPIHPPDPPTRVKIIDVSKGIVTLTWKPP 7402 Query: 528 NKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMFI 586 G + + Y +E ++ SGN W RR + T + V+ L G Y F Sbjct: 7403 KNDGGAPVTHYNIERLWWDS-SGN----QQESWRQCNRRDIDTTTFKVEDLHEGAEYEFR 7457 Query: 587 VRTENSHGLSGPSPVSDSVTVGDDSNS 613 V+ N G S PS + + V D + + Sbjct: 7458 VKAVNEVGASRPSSTAGPIIVKDQNRA 7484 Score = 57.2 bits (132), Expect = 3e-06 Identities = 81/305 (26%), Positives = 129/305 (42%), Gaps = 36/305 (11%) Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363 V++G+ G P PT W EGN + K+ + T LTI++ + Sbjct: 8666 VKAGSTILLPAVMLGIPTPTAKWQSEGNEL-----KTEGKFKIVTEGNSTT-LTISECAR 8719 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN--QTLPIKSMAVFPCTA 421 DS + + N AGS V L VT D P+ GP N + P + + Sbjct: 8720 TDSGEYSL-TVSNPAGSKSVA--LHVTVLDVPSAPV---GPVNILEVTPDHMIIQWRAPK 8773 Query: 422 ICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLK-DLDKSDSGTYTCVASSRHGKYVWS 479 P++++ E + + + +V + G+ K + + + G V K + Sbjct: 8774 DDGGSPLMSYVVEKKDVKKPWEPWSVVSSGSTSTKAKVPRLEKGREYIVRVRAENK-IGI 8832 Query: 480 GALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQ 539 GA L +SP P I A + PGPP +P ++T+ +VT+SW++ G S + GY Sbjct: 8833 GAGL-ESP--PTI----AKQMFDPPGPPGQPTCSDITENAVTVSWAEPETDGGSPVSGYI 8885 Query: 540 VEVFSRETLSGNNTPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598 VE R ++G W+ + + V Y V L G +Y F + EN G+S P Sbjct: 8886 VE---RREMTGK--------WIRVNKTPVLDIRYRVCGLFEGNSYEFRIFAENVAGVSQP 8934 Query: 599 SPVSD 603 S SD Sbjct: 8935 SYPSD 8939 Score = 56.8 bits (131), Expect = 3e-06 Identities = 72/276 (26%), Positives = 113/276 (40%), Gaps = 46/276 (16%) Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562 +P PP N+T + L W++ + G S I Y VE R+ R W Sbjct: 5445 VPNPPRWLEVVNITKINCDLKWTEPDSDGGSPITNYVVE--KRDV--------RRRTWQA 5494 Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSN 622 + V T Y V L G Y+F V EN+ G+S + DSV D T + Sbjct: 5495 VDTTVKDTKYTVTPLSEGSLYVFRVAAENAVGISEFCELEDSVLAKD--------TFTTP 5546 Query: 623 STEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKT 682 Y LT +VE + + + L WE N +G RP+ IE + K Sbjct: 5547 GPPY---ALT--VVE------VSKRHVDLKWEPPN---SDG----GRPITKYVIEKKEKV 5588 Query: 683 ---ILHSNDVSG----FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDV--PDG 733 + S SG + +T + + T+ +F + + G PS V T++D P Sbjct: 5589 GTRWVKSGKTSGPESKYRVTDVDEGTEVQFQVRAENEAGVGHPSEPTVIMTIEDAISPPS 5648 Query: 734 PPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNV 769 PP+ +++ + +++ W PE + ITGY+V Sbjct: 5649 PPLEVKIVDASREHINITWKAPE-KNGGSPITGYHV 5683 Score = 55.6 bits (128), Expect = 8e-06 Identities = 51/179 (28%), Positives = 75/179 (41%), Gaps = 32/179 (17%) Query: 425 PEPIIAWYFEGEALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481 P P W ++ + R V N L++KD+ + DSG Y+ VA + GK + Sbjct: 10020 PAPACQWKRGENNVVSSSRLAVHKSQNMCVLIIKDVSRQDSGEYSLVAENSSGKIEQTLK 10079 Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSV-TLSWSQNNKIGSSSILGYQV 540 +++ +PGPP P + D+ TLSW++ + G S+I Y V Sbjct: 10080 III----------------RDIPGPPEPPFEISDIDSDACTLSWNKPTEDGGSNITNYVV 10123 Query: 541 EVFSRETLSGNNTPRNSRG-WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598 E SRG WV + + LIPG Y+F VR EN G+S P Sbjct: 10124 EKCD-----------VSRGDWVTALSSCGKAGCRIGKLIPGKEYIFRVRAENRFGISDP 10171 Score = 53.6 bits (123), Expect = 3e-05 Identities = 126/538 (23%), Positives = 183/538 (34%), Gaps = 62/538 (11%) Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73 II D V Q LNC + A +W K + + + +F LR Sbjct: 4005 IITPLKDTQVKEGQEIVLNCEVNSEGAKA-KWLKNNETMFESSKFVMAQRDTVFSLRIKA 4063 Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL-EP-ESKQSAQGDTVVLECLP 131 SD Y TN G +A +++V E ++ EP E + + T+ C Sbjct: 4064 AE-KSDEASYTITLTNQRGEQAKCSA--NISVHEEALKIIEPLEDCEIEEKKTITFTCKV 4120 Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190 R P V W K GQ + + D L I+D D G Y +A T E Sbjct: 4121 NR--PNVTVQWMKAGQEITLSKRILYRVDKDKHTLTIKDCSLADEGEYTVVAGTDKATAE 4178 Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RV 249 I+ L D F C++ + V W R+ G + G R Sbjct: 4179 LIISEAPADFAAQL----RDQTITEFEDAEFTCKLSKEK-AHVKWYRN--GREIREGPRY 4231 Query: 250 KVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306 + DG L + DE EY+C E+ S + P I P V Sbjct: 4232 HLERDGKECKLVVKECRPDDECEYACGVEDK---RSRARLFVEEIPVEIVRPPTDVFEPP 4288 Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH--ATAVFDGVTVLTINDTDKN 364 G+ F + + W N II G DKY + + V I D+ Sbjct: 4289 GSDIVFE-AELNKDRVEVKWM--RNNMIIVQG---DKYQMISEGKVHRLQVCEIRPRDQG 4342 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424 + R IV A R KL + + P I N V Sbjct: 4343 EYR--IV------AKEKDARAKLELAA-----IPKIKTTDQNLVTDAGKPFVMAVPYDAY 4389 Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483 P W+F+ + + + +N+ T LK+ KSD G Y V ++HG +G Sbjct: 4390 PRAEAEWFFD-DISLPGQNIDTSNERTEYRLKEPKKSDQGRYKIVIKNKHG----TGEAF 4444 Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541 ++ DV +PGP + D V+L+W + G S IL Y VE Sbjct: 4445 IN------------LDVIDVPGPVKNLHVVDTADGEVSLAWEEPESDGGSKILAYVVE 4490 Score = 52.0 bits (119), Expect = 1e-04 Identities = 62/230 (26%), Positives = 94/230 (40%), Gaps = 22/230 (9%) Query: 374 AVNYAGSSFVRGKLT-VTSDDDRPPPIITNGPSNQTL---PIKSMAVFPCTAICTPEPII 429 AVN AG S + + + D P+IT ++Q L + P T P P + Sbjct: 7150 AVNAAGESEPSPRTSDIIVQDILEEPVITIDVTSQELLNCRAGTTLKIPATISGKPLPNV 7209 Query: 430 AWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPIN 489 W F+G A + ++N + TL + D D S S T T V + K SG ++ + Sbjct: 7210 TWEFDGTA--PSEKKNERH--TLPV-DSDISSSDT-TSVVTIPESKLHHSGRYIITANNQ 7263 Query: 490 PNIHFFRA-ADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETL 548 + +V LPG P ++T + LSW + G I Y +E ++T+ Sbjct: 7264 AGTKIVKVRVNVLDLPGAPKDITISDITRGTCRLSWKPPDCDGGDRIKSYFIE---KKTV 7320 Query: 549 SGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598 G + W + VV LI G Y+F +R EN G GP Sbjct: 7321 EG-------KAWTKVNPACTTQSLVVPDLIEGQEYLFRIRAENRFGY-GP 7362 Score = 51.2 bits (117), Expect = 2e-04 Identities = 49/211 (23%), Positives = 86/211 (40%), Gaps = 17/211 (8%) Query: 273 EAENSVGAVSASGYLTVYDPPSINLSPNSVNVES--GNVARFTCTATGRPEPTMFWSVEG 330 E ++++ ++ G+ + P + N+ES GN +F C P T W G Sbjct: 203 EEKHTLTGETSQGFTRSEEVPPV-FKKKICNMESNIGNPVKFECEIEETPNVTFKWFKAG 261 Query: 331 NRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT 390 + DK + + L + K+DS C A N GS +L +T Sbjct: 262 SEI-----KQSDKVRIIS-RQTTSSLELPSPTKDDS-GEYSCRASNKHGSDTCSAQLNIT 314 Query: 391 SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT--- 447 + + P SN ++P+ C + + WY +G+ L ++R N T Sbjct: 315 ASE---PARFLRKLSNISIPMSQKLRLECKFTGDRKLFVTWYKDGKQLYASYRYNTTVTD 371 Query: 448 NDGTL-VLKDLDKSDSGTYTCVASSRHGKYV 477 N TL L++ D + +G Y+C S+ G+ + Sbjct: 372 NSCTLESLQECDNTTTGIYSCEVSNAFGREI 402 Score = 50.4 bits (115), Expect = 3e-04 Identities = 59/231 (25%), Positives = 94/231 (40%), Gaps = 31/231 (13%) Query: 6 VTSGEAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64 +T + P + PL +TV+ + L+C GSP I+W K V S + Sbjct: 887 ITEQKRPPTFDIPLKPMTVSEGERLNLSCHVCGSPPVKIQWMKDRREVTSSASTKMTFVD 946 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNA------------------TLHVAVL 106 G L +DAG Y C+ATN+ G+ S+ T A Sbjct: 947 GTATLEINQAS-KTDAGDYLCKATNNAGSEFSKTKVTIKDKAGVAPAAAPAAPTTPQATK 1005 Query: 107 REE---FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG 163 + + F EP+S + T G P PNV W K + G R+++ G Sbjct: 1006 KLDNLFFIEEPKSIHIVEKGTATF-IAKVGGDPIPNVKWMKGKWRQMTHG-GRINIQQKG 1063 Query: 164 N---LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDV 211 L I++ ++D+G+Y+C+A N G E + +++ +GPE V Sbjct: 1064 QESKLEIKEVTKSDSGQYRCVASNKHGEIE---CSTDLNVDEKKESGPEVV 1111 Score = 50.4 bits (115), Expect = 3e-04 Identities = 35/114 (30%), Positives = 50/114 (43%), Gaps = 4/114 (3%) Query: 499 DVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558 D LPGPP +P + T +S+ ++W G S+I GY +E R + + R Sbjct: 6961 DPFGLPGPPQRPRIISHTRSSMVVTWEPPKDNGGSTIQGYWLEKRERGAVYWSRVNRAP- 7019 Query: 559 GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSN 612 V V Y V LI G Y F V +N+ G+ PS ++ V D N Sbjct: 7020 ---VTKPAVKGLEYNVLHLIEGAEYKFRVMAQNAAGVGPPSEATECVFALDPRN 7070 Score = 48.8 bits (111), Expect = 9e-04 Identities = 45/185 (24%), Positives = 72/185 (38%), Gaps = 29/185 (15%) Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRNV-TNDG--TLVLKDLDKSDSGTYTCVASSRHG 474 P + PEP + W L R + T G TL + + +SD+ TY A + G Sbjct: 5073 PADVLGKPEPRVKWTKADLVLKPEERITIDTKPGHSTLSIANTTRSDTATYIIEAVNTSG 5132 Query: 475 KYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSS 534 + VD ++ PGPP +T+ S L+W+ G S Sbjct: 5133 R----ATATVD------------VNILDKPGPPAAFDISEITNESCCLAWNAPRDDGGSP 5176 Query: 535 ILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHG 594 + Y VE+ P + W ++ + QT + L+P Y+F V EN +G Sbjct: 5177 VANYIVEM----------RPTDKEEWQKLSATIKQTAFKATKLVPLKEYVFRVSAENQYG 5226 Query: 595 LSGPS 599 + P+ Sbjct: 5227 IGTPA 5231 Score = 48.0 bits (109), Expect = 0.002 Identities = 35/104 (33%), Positives = 50/104 (48%), Gaps = 4/104 (3%) Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRY 178 +G V L+ +P G P P V WKK L D N L+I+D ++TDA +Y Sbjct: 11092 EGSNVRLK-IPIIGKPTPAVSWKKGEDENLTDTGRVCVESTAVNTTLLIRDCQRTDASKY 11150 Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQ 222 RN+AGT+ES I +++ KP + GP T T + Sbjct: 11151 TITLRNSAGTKESTI-FVRVVGKPGIPNGPIKFKEVTADGATLK 11193 Score = 47.6 bits (108), Expect = 0.002 Identities = 28/97 (28%), Positives = 47/97 (48%), Gaps = 4/97 (4%) Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILA 265 E +V + GS++ + G P P W+ S G G+ K++ +G+ L + Sbjct: 8662 EGLVVKAGSTILLPAVMLGIPTPTAKWQ-SEGNELKTEGKFKIVTEGNSTTLTISECART 8720 Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302 D GEYS N G+ S + ++TV D PS + P ++ Sbjct: 8721 DSGEYSLTVSNPAGSKSVALHVTVLDVPSAPVGPVNI 8757 Score = 47.2 bits (107), Expect = 0.003 Identities = 30/102 (29%), Positives = 46/102 (45%), Gaps = 12/102 (11%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV-- 561 PGPP P + T++++ L+W++ G S ILGY VE N+ W+ Sbjct: 10685 PGPPISPKAIDTTNSTIKLTWTKPANDGGSDILGYLVEC----------KRINTTDWIRC 10734 Query: 562 VIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603 + + + T+YVV L+ Y V N G S P V + Sbjct: 10735 NVPKNLQDTNYVVTGLLENSEYQLRVSAVNKIGFSQPCEVPE 10776 Score = 46.8 bits (106), Expect = 0.004 Identities = 37/132 (28%), Positives = 56/132 (42%), Gaps = 13/132 (9%) Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543 V P P + D S P PP + + + + ++W K G S I GY VE+ Sbjct: 5628 VGHPSEPTV-IMTIEDAISPPSPPLEVKIVDASREHINITWKAPEKNGGSPITGYHVELS 5686 Query: 544 SRETLSGNNTPRNSRGWVVI-ARRVHQTHY-VVKSLIPGITYMFIVRTENSHGLSGPSPV 601 ET W+ I R V + + + +IP Y+ VR N+ G+S PS + Sbjct: 5687 EAET----------EKWMRINPRPVKELRFKAEEGIIPEKKYVLRVRAINAIGVSDPSEI 5736 Query: 602 SDSVTVGDDSNS 613 SD V D ++ Sbjct: 5737 SDGVFAKDPDSA 5748 Score = 46.0 bits (104), Expect = 0.006 Identities = 37/112 (33%), Positives = 48/112 (42%), Gaps = 12/112 (10%) Query: 491 NIHFFRAA--DVSSL--PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRE 546 N H F A DV+ L PGPP + +TSV +W G S I+ Y +E Sbjct: 6152 NAHGFATASCDVNVLDKPGPPVNFGFDEIRNTSVVCTWDAPLDDGGSEIINYILE----- 6206 Query: 547 TLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598 +NT + GWV + +Y V LI G Y+F V EN G P Sbjct: 6207 --KKDNTS-DDIGWVTVTSTHKGYNYPVTKLIEGKEYIFRVTAENKFGCGHP 6255 Score = 46.0 bits (104), Expect = 0.006 Identities = 33/116 (28%), Positives = 52/116 (44%), Gaps = 11/116 (9%) Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRY 178 G T++L + G P P W+ G L +G + +V GN L I + +TD+G Y Sbjct: 8669 GSTILLPAVM-LGIPTPTAKWQSEGNELKTEG--KFKIVTEGNSTTLTISECARTDSGEY 8725 Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV----GGDPL 230 N AG++ A+ + + P GP +++ T + Q R GG PL Sbjct: 8726 SLTVSNPAGSKSVALHVTVLDV-PSAPVGPVNILEVTPDHMIIQWRAPKDDGGSPL 8780 Score = 45.6 bits (103), Expect = 0.008 Identities = 74/330 (22%), Positives = 128/330 (38%), Gaps = 37/330 (11%) Query: 496 RAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPR 555 +A D+ +P P +P +V + S + W++ G I Y +E ++ S R Sbjct: 8242 KAKDLFRVPEAPEQPTVKDVYNDSALVIWNRPRD-GGKPITNYILE---KKEPSAKRWSR 8297 Query: 556 NSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLW 615 +R + A T Y V+ L+ G Y F V EN G PS S + D Sbjct: 8298 ATRDPIYPA-----TQYRVQELVEGCEYEFRVTAENEIGTGDPSVPSKPILAKDP----- 8347 Query: 616 EGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNI- 674 I+ L EA ++ L W + +F Y Sbjct: 8348 --------------IVLPSPPVLPEAVDKTKDSVSLSWRVPRHDGKGKIFGYLIEYQKPG 8393 Query: 675 TIEY-EMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPD- 732 IE+ + S + F +T+L + +++F ++ + +P+ + + D D Sbjct: 8394 AIEWVKANETPESCPDTKFVVTNLPEGEEFQFRIMAVNAAGKSEPAYVKEPVKVHDRLDK 8453 Query: 733 -GPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQ 791 GPP N+ + + + + +L W PE +I+ Y +V DV A ++ V + + Sbjct: 8454 PGPPRNLAISEITSESAYLTWQKPE-DDGGAVISHY--IVQKKDVAA-ENWVPV-CAASK 8508 Query: 792 ATSLIMTNLTSGVSYSVQIAAETIIGLGPF 821 SL+ L G Y ++AAE G F Sbjct: 8509 KLSLMAQYLMEGTQYLFRVAAENQFGRSAF 8538 Score = 45.6 bits (103), Expect = 0.008 Identities = 30/105 (28%), Positives = 49/105 (46%), Gaps = 7/105 (6%) Query: 507 PTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARR 566 P KP +VT +V+L W++ G S I+GY VE L G+ R + ++ Sbjct: 10287 PGKPEVLDVTKNAVSLVWTKPKNDGGSKIIGYYVEAM---RLPGDTWVRCNTS----SQN 10339 Query: 567 VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDS 611 V + Y L G Y F V + + +S PS ++D + V ++ Sbjct: 10340 VPREEYTATGLEEGANYQFRVIAKTAVNISRPSEITDPILVSAEN 10384 Score = 44.8 bits (101), Expect = 0.015 Identities = 38/153 (24%), Positives = 64/153 (41%), Gaps = 18/153 (11%) Query: 460 SDSGTYTCVAS-SRH--GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVT 516 +D+ T CV +R+ GKY+ L +DS ++ V PGPP + + Sbjct: 10841 TDTDTLVCVEKVNRYDAGKYI----LNLDSVSGMKMYTV-IVKVLDTPGPPLNLMIKETS 10895 Query: 517 DTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKS 576 S ++ W + G S I GY V+ E + W + +T + ++ Sbjct: 10896 KDSASILWDEPLIDGGSEITGYIVDKRDAER----------KAWSNVTTSCTKTSFKIED 10945 Query: 577 LIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 L PG +Y F V +N +G+ P D+V + Sbjct: 10946 LEPGRSYCFRVLAQNQYGIGEPCETVDAVRASE 10978 Score = 44.4 bits (100), Expect = 0.019 Identities = 78/335 (23%), Positives = 127/335 (37%), Gaps = 38/335 (11%) Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGN--NTP 554 A D + P P P+ + + +SV+LSW+ ++ G S I GY VEV + NTP Sbjct: 7065 ALDPRNPPSQPPAPVVTDKSPSSVSLSWTPPDRDGGSPIKGYIVEVQDEGSHEWKRINTP 7124 Query: 555 RNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSL 614 + + Y V L F + N+ G S PSP + + V D Sbjct: 7125 ---------DKLILTNSYTVPGLKENKKCRFRIVAVNAAGESEPSPRTSDIIVQDILEEP 7175 Query: 615 WEGTGVSNSTEYRN--NILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLD 672 V+ S E N T I I P+ + T WE F P + Sbjct: 7176 VITIDVT-SQELLNCRAGTTLKIPATISGKPLPNVT----WE----------FDGTAPSE 7220 Query: 673 NITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPD 732 + E T+ +D+S + TS+ + + Y + +++ + +V D Sbjct: 7221 K---KNERHTLPVDSDISSSDTTSVVTIPESKLHHSGRYIITANNQAGTKIVKVRVNVLD 7277 Query: 733 --GPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH 790 G P +I + + T L W PP+ I Y + ++ K+ +N Sbjct: 7278 LPGAPKDITISDITRGTCRLSWKPPDCD-GGDRIKSYFIEKKTVE---GKAWTKVNPAC- 7332 Query: 791 QATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825 SL++ +L G Y +I AE G GP + + Sbjct: 7333 TTQSLVVPDLIEGQEYLFRIRAENRFGYGPHTTTI 7367 Score = 44.0 bits (99), Expect = 0.025 Identities = 37/127 (29%), Positives = 55/127 (43%), Gaps = 13/127 (10%) Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543 V P P+ F ++ P PPT +T + T T+ L W K G S I+GY VE + Sbjct: 7641 VGPPSEPSEPTFAREPIAP-PSPPTPKVT-DWTKTTADLEWIPPLKDGGSKIIGYFVE-Y 7697 Query: 544 SRETLSGNNTPRNSRGWVVIA-RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602 E + WV + V T +V+ L + F V N+ GL P V+ Sbjct: 7698 KEE---------GTEAWVKAKDKEVRGTKFVITGLKENALFKFRVIALNAAGLGEPGEVA 7748 Query: 603 DSVTVGD 609 D++ + D Sbjct: 7749 DALEMKD 7755 Score = 43.6 bits (98), Expect = 0.034 Identities = 30/84 (35%), Positives = 42/84 (50%), Gaps = 5/84 (5%) Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRY 178 GD V +E G P+P V W K G T R+ + G N L + ++R+ D G+Y Sbjct: 9361 GDAVSIEA-ELLGKPQPEVKWSKEGDTRDISKGLRVQVETGTNFTKLQLSNSRRGDTGKY 9419 Query: 179 QCIARNAAGTRESAIATLKIHIKP 202 A NAAGT SA A + + +P Sbjct: 9420 IITATNAAGTC-SAEAKVNVLDRP 9442 Score = 43.6 bits (98), Expect = 0.034 Identities = 38/136 (27%), Positives = 54/136 (39%), Gaps = 15/136 (11%) Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSS 533 GKY +L V SP F V PGP ++T +S L+WS G S Sbjct: 9728 GKY----SLNVSSPAGEKAVFVNVK-VLDTPGPVDGLEVTDMTMSSCNLTWSPPETDGGS 9782 Query: 534 SILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSH 593 ++ Y VE RE + + W + V +T + + +L+PG Y F V N + Sbjct: 9783 NVTHYIVE--KREI--------DRKTWATVKANVEKTTFKISNLVPGTEYYFRVVAVNEY 9832 Query: 594 GLSGPSPVSDSVTVGD 609 G P S D Sbjct: 9833 GPGVPRVTPKSYLASD 9848 Score = 43.2 bits (97), Expect = 0.044 Identities = 66/294 (22%), Positives = 126/294 (42%), Gaps = 36/294 (12%) Query: 495 FRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTP 554 F A D PGP + + + TS+TL+W++ G + ++GY VE+ + T Sbjct: 9633 FTARDPVEPPGPVSNLKVTDSSKTSITLAWTKPTYDGGAPLIGYVVEIRVKGT-----GK 9687 Query: 555 RNSRGW--VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSN 612 + GW +A ++ T + V SL + Y F V ++ SG ++ S G+ Sbjct: 9688 KGDEGWKRCNVAAQLIGTEFTVSSLDEKLEYEFRVTRDD----SGKYSLNVSSPAGE--K 9741 Query: 613 SLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMW---EILNFYYLEGLFIYFR 669 +++ V + T V+ +E T + + L W E + + R Sbjct: 9742 AVFVNVKVLD---------TPGPVDGLEVTDMTMSSCNLTWSPPETDGGSNVTHYIVEKR 9792 Query: 670 PLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKP---SNSRVAQT 726 +D T T+ + + + F+I++L T+Y F ++ + G P S +A Sbjct: 9793 EIDRKT----WATVKANVEKTTFKISNLVPGTEYYFRVVAVNEYGPGVPRVTPKSYLASD 9848 Query: 727 LDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANK 780 PD PP +++ ++ + + W P ++ I GY V+++L++P K Sbjct: 9849 PVSKPD-PPQKVDVLEISKNSATVGWVKP-MRDGGAKIDGY--VIDYLELPMPK 9898 Score = 42.7 bits (96), Expect = 0.059 Identities = 34/137 (24%), Positives = 55/137 (40%), Gaps = 6/137 (4%) Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LV 453 PP+ N I + F C TP W+ G + Q+ + + + T L Sbjct: 223 PPVFKKKICNMESNIGNPVKFECEIEETPNVTFKWFKAGSEIKQSDKVRIISRQTTSSLE 282 Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITH 513 L K DSG Y+C AS++HG S L + + + F R S+P + Sbjct: 283 LPSPTKDDSGEYSCRASNKHGSDTCSAQLNITA--SEPARFLRKLSNISIPMSQKLRLEC 340 Query: 514 NVT-DTSVTLSWSQNNK 529 T D + ++W ++ K Sbjct: 341 KFTGDRKLFVTWYKDGK 357 Score = 42.3 bits (95), Expect = 0.078 Identities = 37/141 (26%), Positives = 60/141 (42%), Gaps = 6/141 (4%) Query: 159 LVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL----ITGPEDVVAQ 214 +V G ++ I ++ R++ ARN+ G+ IK + I E V A+ Sbjct: 9946 VVKGLSISIAGLKEGRKYRFRVAARNSMGSSLPTETREAYEIKEQMFEPKIIMTELVTAK 10005 Query: 215 TGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSC 272 G+ + + V G P P W+R + L K + L + +V D GEYS Sbjct: 10006 AGAKLRVEALVSGKPAPACQWKRGENNVVSSSRLAVHKSQNMCVLIIKDVSRQDSGEYSL 10065 Query: 273 EAENSVGAVSASGYLTVYDPP 293 AENS G + + + + D P Sbjct: 10066 VAENSSGKIEQTLKIIIRDIP 10086 Score = 41.9 bits (94), Expect = 0.10 Identities = 33/104 (31%), Positives = 47/104 (45%), Gaps = 13/104 (12%) Query: 496 RAADVSSLPGPPTKPITHNVTD-TSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTP 554 +A D PGPP K + H D T V L W ++ G S I G+ VE + Sbjct: 8546 KAVDPLYPPGPP-KNLHHVDADKTEVWLQWEWPDRTGGSEITGFIVE----------HQE 8594 Query: 555 RNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598 + WV + V V L+ G TY F V+++N+ G+S P Sbjct: 8595 EGATDWVTF-KTVSNPQCHVTGLVEGKTYRFRVKSQNAIGISRP 8637 Score = 41.5 bits (93), Expect = 0.14 Identities = 32/100 (32%), Positives = 47/100 (47%), Gaps = 5/100 (5%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 PG KP +VT S+T++W + G S I GY +E R+ + R +R V Sbjct: 7555 PGQCEKPTISSVTIDSMTVNWEEPESDGGSPITGYWLE---RKETTSKRWSRVTRD-PVR 7610 Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603 + +H V LI G Y+F V N+ G+ PS S+ Sbjct: 7611 PMPMGVSHRVT-GLIEGSQYLFRVSAINAAGVGPPSEPSE 7649 Score = 41.1 bits (92), Expect = 0.18 Identities = 31/106 (29%), Positives = 42/106 (39%), Gaps = 9/106 (8%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 P PP + N T S+T++W G I GY +E ++ G+ R + Sbjct: 5942 PDPPIEVAGLNPTSNSITVTWMAPPYDGGCPITGYIIEKIEKD---GDRFER------CV 5992 Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 V Y V L G Y F VR EN G S PS + + D Sbjct: 5993 PNLVPGFSYTVTGLTEGKEYQFRVRAENIAGASDPSRSTPLIMAAD 6038 Score = 41.1 bits (92), Expect = 0.18 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 4/87 (4%) Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS----LRLDNVILAD 266 +V + G +V+ + + G P P+V W + ++ G ++ G+ L+L N D Sbjct: 9356 LVVKAGDAVSIEAELLGKPQPEVKWSKEGDTRDISKGLRVQVETGTNFTKLQLSNSRRGD 9415 Query: 267 EGEYSCEAENSVGAVSASGYLTVYDPP 293 G+Y A N+ G SA + V D P Sbjct: 9416 TGKYIITATNAAGTCSAEAKVNVLDRP 9442 Score = 40.7 bits (91), Expect = 0.24 Identities = 38/163 (23%), Positives = 71/163 (43%), Gaps = 15/163 (9%) Query: 122 GDTVVLECLPPRGSPEPNVY-WKKNGQTLLFDGDSRMHLVDGGNLVIQ--DARQTDAGRY 178 G + V EC + SP + W K+G + + DG + +Q D + +D G Y Sbjct: 2676 GSSAVFEC---QISPSTAITTWMKDGSNIR-ESPKHKFTSDGKDRKLQIIDVQLSDTGEY 2731 Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 C+A+ +++ A L + P T E+ G + C + D DV+W+ Sbjct: 2732 TCVAK-LGNKEKTSTAKLVVEELPVKFTKNLEEETSVLKGQPMYLTCELSKD--KDVVWK 2788 Query: 237 RSAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAEN 276 ++ G++++ G ++ + ++ D G Y+CE EN Sbjct: 2789 KNGKELKEIPGKIQINIIGLQRAVTIQDMNDDDAGVYTCECEN 2831 Score = 40.3 bits (90), Expect = 0.31 Identities = 35/100 (35%), Positives = 48/100 (48%), Gaps = 15/100 (15%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV-V 562 P P P VT ++V LSW + GS ILGY VE RE NS+ W+ V Sbjct: 6270 PDAPNVPRIGEVTSSTVALSWHEPKDNGSP-ILGYWVE--RREV--------NSKYWIRV 6318 Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602 + + + V+ L+ G+ Y+F V EN L+GP S Sbjct: 6319 NSNLLSALNVKVEGLMEGLVYVFRVCAEN---LAGPGEFS 6355 Score = 39.9 bits (89), Expect = 0.41 Identities = 23/65 (35%), Positives = 38/65 (58%), Gaps = 7/65 (10%) Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMH----LVDGGNLVIQDARQTDAGRYQCIARNAAGT 188 +G P+P + W K+ + L D + M+ LV+ LVIQDA + D G+Y A+N++G Sbjct: 9078 KGRPDPEITWTKDARVLGRDKRTEMNNNFPLVE---LVIQDAVRADYGKYAIQAKNSSGQ 9134 Query: 189 RESAI 193 ++ I Sbjct: 9135 AQATI 9139 Score = 39.9 bits (89), Expect = 0.41 Identities = 43/158 (27%), Positives = 64/158 (40%), Gaps = 11/158 (6%) Query: 134 GSPEPNVYWKKNGQTLLFDGDSRM----HLVDGGNLVIQDARQTDAGRYQCIARNAAG-- 187 G P P V W KNG+TL D + +M HL +L + + AG Y A NA+G Sbjct: 10415 GKPMPKVTWSKNGETLKADKEFKMSQKRHLF---SLSLDAVTKLHAGNYGIHAANASGNT 10471 Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD-VLWRRSAGGGNMPL 246 T E + L I P + E + + S GG P+ + V+ +R Sbjct: 10472 TAEIQLKILDIPGPPASVKLDEILSDRVKLSWEAPLVDGGSPITNYVVDKRETSRAEWAQ 10531 Query: 247 GRVKV-LDDGSLRLDNVILADEGEYSCEAENSVGAVSA 283 K+ D ++ +I E ++ AEN G A Sbjct: 10532 VSAKISRDTTECSVERLIEGHEYQFRVRAENHYGTGDA 10569 Score = 39.5 bits (88), Expect = 0.55 Identities = 35/123 (28%), Positives = 53/123 (43%), Gaps = 9/123 (7%) Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTC 467 I S AVF C I I W +G + ++ + T+DG L + D+ SD+G YTC Sbjct: 2675 IGSSAVFECQ-ISPSTAITTWMKDGSNIRESPKHKFTSDGKDRKLQIIDVQLSDTGEYTC 2733 Query: 468 VASSRHGKYVWSGALLVDS-PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQ 526 VA + + + L+V+ P+ + + S L G P D V W + Sbjct: 2734 VAKLGNKEKTSTAKLVVEELPVKFTKNL--EEETSVLKGQPMYLTCELSKDKDVV--WKK 2789 Query: 527 NNK 529 N K Sbjct: 2790 NGK 2792 Score = 39.5 bits (88), Expect = 0.55 Identities = 69/310 (22%), Positives = 117/310 (37%), Gaps = 34/310 (10%) Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363 V++G+ G+P+P + WS EG+ I G+ T T L ++++ + Sbjct: 9358 VKAGDAVSIEAELLGKPQPEVKWSKEGDTRDISKGLRVQVETGT----NFTKLQLSNSRR 9413 Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA--VFPCTA 421 D+ I+ +A N AG+ K+ V DRP PI S+ ++ +A + Sbjct: 9414 GDTGKYII-TATNAAGTCSAEAKVNVL---DRPGPIRDLKVSDISIDRCKLAWEIPEDDG 9469 Query: 422 ICTPEPIIAWYFEGEALIQN-HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480 C I E + + + H + + V + L + + + A ++ G +G Sbjct: 9470 GCEIYNYIIEKCEAKRGVWSIHSAAIITNSAKVTR-LIEGNEYIFRVRAENKMG----AG 9524 Query: 481 ALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQV 540 + I F R P P +T DT V + W + G I GY + Sbjct: 9525 PAVESESIIARTQFSR----PGAPDAP--EVTKITKDTMVVM-WCSPDNDGGKPITGYIL 9577 Query: 541 EVFSRETLSGNNTPRNSRGWVVIARRVHQ-THYVVKSLIPGITYMFIVRTENSHGLSGPS 599 E + W + + + T V SL+P Y F V+ EN G+ S Sbjct: 9578 EKKEEHAIR----------WAPVVKSPYAGTQMTVTSLLPNHEYQFRVKAENEIGVGDAS 9627 Query: 600 PVSDSVTVGD 609 S + T D Sbjct: 9628 KPSRTFTARD 9637 Score = 39.1 bits (87), Expect = 0.72 Identities = 30/105 (28%), Positives = 41/105 (39%), Gaps = 11/105 (10%) Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562 +PG P + V + ++W + G S + GY +E RNS WV Sbjct: 10185 VPGEPLNCRINKVNKDCMFVAWDKPESDGGSPVTGYYIE----------RKERNSLLWVK 10234 Query: 563 IARRV-HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVT 606 V T Y LI G+ Y F V N G PS +D +T Sbjct: 10235 ANDSVVRTTEYPCAGLIEGLEYTFRVSAINRAGQGKPSKKTDFIT 10279 Score = 38.7 bits (86), Expect = 0.96 Identities = 39/146 (26%), Positives = 58/146 (39%), Gaps = 16/146 (10%) Query: 160 VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK-----PYL---ITGPEDV 211 V G VI ++ +++ IA NAAG E + +K P L ++ E + Sbjct: 7713 VRGTKFVITGLKENALFKFRVIALNAAGLGEPGEVADALEMKDRTILPVLELDVSVKEKM 7772 Query: 212 VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVI----LADE 267 V G + V G P P + W R P+ V++ S+ VI A Sbjct: 7773 VIHAGGVIRILAYVSGQPPPVITWSRD----EYPVPSEAVIETTSISCSMVIKDCTRAQR 7828 Query: 268 GEYSCEAENSVGAVSASGYLTVYDPP 293 G Y+ A+N G V S + V D P Sbjct: 7829 GVYTITAKNDGGEVKKSVIVEVLDVP 7854 Score = 38.3 bits (85), Expect = 1.3 Identities = 29/109 (26%), Positives = 52/109 (47%), Gaps = 11/109 (10%) Query: 367 RNTIVCSA--VNYAGSSFV-RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423 R+ I+ A V FV + KLTV + PP + +QT+ ++ A+ C + Sbjct: 3618 RDVIMTEAGEVKLTAKDFVTQAKLTV----NEPPVEFSKPLEDQTVEEEATAILECE-LS 3672 Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVA 469 + + W+ +G+ + + + + +G L++KD DS TYTC A Sbjct: 3673 REKADVKWFRDGQEIRKTKKHEMVAEGRIRRLIIKDCSLDDSKTYTCDA 3721 Score = 38.3 bits (85), Expect = 1.3 Identities = 37/118 (31%), Positives = 48/118 (40%), Gaps = 15/118 (12%) Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556 A S PGP T VT S TLSW + G S I+ Y +EV L+G + Sbjct: 10973 AVRASEQPGPVMDFKTLLVTKDSCTLSWKKPISDGGSRIIAYVLEV-----LNGEDK--- 11024 Query: 557 SRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSL 614 W + R + Y K L+ G Y + V N SG PV + + D N L Sbjct: 11025 ---WKELLRSKNM-QYSAKDLVEGREYKYRVFATND---SGDGPVKELSVLAKDINVL 11075 Score = 37.9 bits (84), Expect = 1.7 Identities = 31/109 (28%), Positives = 42/109 (38%), Gaps = 10/109 (9%) Query: 499 DVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558 +V + P P VT V L W G S + GY VE RE + + Sbjct: 4845 NVIACPSAPKDFKVAEVTRHHVHLMWEAPEHDGGSPVSGYNVE--KREV--------SRK 4894 Query: 559 GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607 WV + V Y V +I G Y+F V N G P+ + + V V Sbjct: 4895 TWVKVISGVQDLEYTVTDVIEGKEYLFSVIACNKCGPGEPAYIDEPVNV 4943 Score = 37.9 bits (84), Expect = 1.7 Identities = 37/129 (28%), Positives = 49/129 (37%), Gaps = 17/129 (13%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 PGPP I +VT+T++ +SW G ILGY VE L G + WV Sbjct: 6370 PGPPVPKIV-DVTNTTIDISWQPPLYNGGGEILGYHVE----RCLVG------EKDWVRC 6418 Query: 564 AR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSN 622 R Y V L G Y V N G P +++ V + E GV Sbjct: 6419 TEFRCKDRKYTVTGLTEGADYNLRVYAVNEGGHGAPG-MTEPVQAKEPE----EAPGVEF 6473 Query: 623 STEYRNNIL 631 RN ++ Sbjct: 6474 DISVRNGVI 6482 Score = 37.5 bits (83), Expect = 2.2 Identities = 27/100 (27%), Positives = 41/100 (41%), Gaps = 11/100 (11%) Query: 500 VSSLPGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558 V+ P PP P+ + V + +SW G S I Y +E R+ N Sbjct: 8146 VADRPLPPEGPVVFDEVHRDHMVISWKPPLDDGGSEISNYIIE--KRDV--------NRD 8195 Query: 559 GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598 W + +TH V L+ G Y+ + EN +G+S P Sbjct: 8196 MWTTVTSATTKTHCKVPKLVEGREYILRISAENMYGISDP 8235 Score = 37.1 bits (82), Expect = 2.9 Identities = 18/43 (41%), Positives = 24/43 (55%) Query: 499 DVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541 DV +PGP T NV+ ++L+WS G S I+GY VE Sbjct: 6559 DVMDVPGPVVDLKTVNVSKKMISLTWSDPLDNGGSDIMGYVVE 6601 Score = 37.1 bits (82), Expect = 2.9 Identities = 26/80 (32%), Positives = 40/80 (50%), Gaps = 10/80 (12%) Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIARNAAGTRE 190 G P P WK+ ++ SR+ + N L+I+D + D+G Y +A N++G E Sbjct: 10018 GKPAPACQWKRGENNVV--SSSRLAVHKSQNMCVLIIKDVSRQDSGEYSLVAENSSGKIE 10075 Query: 191 SAIATLKIHIKPYLITGPED 210 TLKI I+ I GP + Sbjct: 10076 Q---TLKIIIRD--IPGPPE 10090 Score = 36.3 bits (80), Expect = 5.1 Identities = 30/117 (25%), Positives = 50/117 (42%), Gaps = 10/117 (8%) Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556 A D +P P K T ++TL+W G S I+GY +E +++ + RN Sbjct: 6655 AVDPKGVPSAPEKLRYTERTKNTITLTWEAPRSDGGSPIIGYYIEKMRQDSNEYDVANRN 6714 Query: 557 SRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNS 613 + I +++L + + F V+ N G PS + SV + +D NS Sbjct: 6715 LCKDLTI---------TLENLTENMMFDFRVKAVNEVGNGEPSK-AISVNIQEDENS 6761 Score = 36.3 bits (80), Expect = 5.1 Identities = 25/89 (28%), Positives = 42/89 (47%), Gaps = 10/89 (11%) Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS------LRLDNVIL 264 + + G + RV G P P++ W + A LGR K + + L + + + Sbjct: 9063 LTVRAGQIINLVTRVKGRPDPEITWTKDA----RVLGRDKRTEMNNNFPLVELVIQDAVR 9118 Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPP 293 AD G+Y+ +A+NS G A+ + V D P Sbjct: 9119 ADYGKYAIQAKNSSGQAQATIIVNVLDIP 9147 Score = 35.9 bits (79), Expect = 6.7 Identities = 32/132 (24%), Positives = 58/132 (43%), Gaps = 9/132 (6%) Query: 177 RYQCIARNAAG---TRESAIATLKIHIKPY--LITGPE-DVVAQTGSSVTFQCRVGGDPL 230 +Y+ A N +G +E ++ I++ P L P + +A+ GS+V + + G P Sbjct: 11048 KYRVFATNDSGDGPVKELSVLAKDINVLPSCDLRDLPNLNYIAKEGSNVRLKIPIIGKPT 11107 Query: 231 PDVLWRRSAGGGNMPLGRVKVLD---DGSLRLDNVILADEGEYSCEAENSVGAVSASGYL 287 P V W++ GRV V + +L + + D +Y+ NS G ++ ++ Sbjct: 11108 PAVSWKKGEDENLTDTGRVCVESTAVNTTLLIRDCQRTDASKYTITLRNSAGTKESTIFV 11167 Query: 288 TVYDPPSINLSP 299 V P I P Sbjct: 11168 RVVGKPGIPNGP 11179 Score = 35.5 bits (78), Expect = 8.9 Identities = 39/164 (23%), Positives = 68/164 (41%), Gaps = 17/164 (10%) Query: 209 EDVVAQT----GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDN 261 +D+V Q GSS F+C++ P + G + K DG L++ + Sbjct: 2665 QDIVLQEAESIGSSAVFECQIS--PSTAITTWMKDGSNIRESPKHKFTSDGKDRKLQIID 2722 Query: 262 VILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN---SVNVESGNVARFTCTATG 318 V L+D GEY+C A+ +++ L V + P + + N +V G TC + Sbjct: 2723 VQLSDTGEYTCVAKLGNKEKTSTAKLVVEELP-VKFTKNLEEETSVLKGQPMYLTCELS- 2780 Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362 + + W G PG + + + + VT+ +ND D Sbjct: 2781 -KDKDVVWKKNGKELKEIPG--KIQINIIGLQRAVTIQDMNDDD 2821 Score = 35.5 bits (78), Expect = 8.9 Identities = 31/114 (27%), Positives = 44/114 (38%), Gaps = 11/114 (9%) Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556 A D + PGPP V+ V L W N G I Y +E +E + Sbjct: 5539 AKDTFTTPGPPYALTVVEVSKRHVDLKWEPPNSDGGRPITKYVIE--KKEKVGTR----- 5591 Query: 557 SRGWVVIARRV-HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 WV + ++ Y V + G F VR EN G+ PS + +T+ D Sbjct: 5592 ---WVKSGKTSGPESKYRVTDVDEGTEVQFQVRAENEAGVGHPSEPTVIMTIED 5642 Score = 35.5 bits (78), Expect = 8.9 Identities = 30/107 (28%), Positives = 48/107 (44%), Gaps = 11/107 (10%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 PGPP+ + + + L W++ ++ G S ILGY VE+ SG S W I Sbjct: 8950 PGPPSNIKLKDWSKSYADLVWTKPSRDGGSPILGYVVEI----QRSG------SAQWDKI 8999 Query: 564 AR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 + + + V L GI Y F ++ N G P ++++V D Sbjct: 9000 NKDLIKFCAFRVPGLNEGIEYRFRIKASNKVGDGEPRELTETVLAKD 9046 >UniRef50_Q6UXM1 Cluster: Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor; n=43; Euteleostomi|Rep: Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor - Homo sapiens (Human) Length = 1119 Score = 106 bits (255), Expect = 3e-21 Identities = 77/298 (25%), Positives = 136/298 (45%), Gaps = 26/298 (8%) Query: 107 REEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVY-WKKNGQTLLFDGDSR--MHL-VDG 162 + + ++PE++ + +G + C S P + WKK+ + LL D + HL G Sbjct: 498 KPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNE-LLHDAEMENYAHLRAQG 556 Query: 163 GNLV-------IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT 215 G ++ +++ G+YQC+ N G+ S A L +++ P P D+ + Sbjct: 557 GEVMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRA 616 Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL----DDGSLRLDNVILADEGEYS 271 G+ +C G P P + W++ GG + P R + + +D + +V + D G YS Sbjct: 617 GAMARLECAAVGHPAPQIAWQKD-GGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYS 675 Query: 272 CEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGN 331 C A+NS G++SA+ LTV + PS V G A C A G P P + W+ + + Sbjct: 676 CTAQNSAGSISANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDS 735 Query: 332 RTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389 ++ +++ A G +L I D+D +D+ C N G+ +L+V Sbjct: 736 PLVV-----TERHFFAA---GNQLLIIVDSDVSDA-GKYTCEMSNTLGTERGNVRLSV 784 Score = 88.2 bits (209), Expect = 1e-15 Identities = 64/220 (29%), Positives = 93/220 (42%), Gaps = 13/220 (5%) Query: 257 LRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315 LRL V A EG+Y C N G+ S LTV PS +P + + +G +AR C Sbjct: 566 LRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLECA 625 Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375 A G P P + W +G FP + H D ++ + K + C+A Sbjct: 626 AVGHPAPQIAWQKDGGTD--FPAARERRMHVMPEDDVFFIVDV----KIEDIGVYSCTAQ 679 Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG 435 N AGS LTV P++ ++T+ AV C A +P P + W + Sbjct: 680 NSAGSISANATLTVLETPSFLRPLL-----DRTVTKGETAVLQCIAGGSPPPKLNWTKDD 734 Query: 436 EALIQNHRRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 L+ R + L++ D D SD+G YTC S+ G Sbjct: 735 SPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLG 774 Score = 87.4 bits (207), Expect = 2e-15 Identities = 63/194 (32%), Positives = 91/194 (46%), Gaps = 16/194 (8%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG---VLVVSDTHRSILP 62 +T P + P+D+T+ A L C A G P+P I W K G + ++P Sbjct: 597 LTVNMLPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMP 656 Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQ 121 +FF+ ++ D GVY C A NS G+ S NATL VL L P + + Sbjct: 657 EDDVFFI--VDVKI-EDIGVYSCTAQNSAGSI-SANATL--TVLETPSFLRPLLDRTVTK 710 Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQ 179 G+T VL+C+ GSP P + W K+ L+ + H GN L+I D+ +DAG+Y Sbjct: 711 GETAVLQCI-AGGSPPPKLNWTKDDSPLVV---TERHFFAAGNQLLIIVDSDVSDAGKYT 766 Query: 180 CIARNAAGTRESAI 193 C N GT + Sbjct: 767 CEMSNTLGTERGNV 780 Score = 82.2 bits (194), Expect = 8e-14 Identities = 62/216 (28%), Positives = 97/216 (44%), Gaps = 5/216 (2%) Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140 G Y C +N +G++ S A L V +L F P G LEC G P P + Sbjct: 577 GKYQCVISNHFGSSYSVKAKLTVNML-PSFTKTPMDLTIRAGAMARLECAAV-GHPAPQI 634 Query: 141 YWKKNGQT-LLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKI 198 W+K+G T + RMH++ ++ I D + D G Y C A+N+AG+ SA ATL + Sbjct: 635 AWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSI-SANATLTV 693 Query: 199 HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLR 258 P + D G + QC GG P P + W + + + L Sbjct: 694 LETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLI 753 Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294 + + ++D G+Y+CE N++G + L+V P+ Sbjct: 754 IVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPTPT 789 Score = 62.9 bits (146), Expect = 5e-08 Identities = 55/218 (25%), Positives = 91/218 (41%), Gaps = 16/218 (7%) Query: 277 SVGAVSASGYLTVYDP-PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII 335 S+ AVS G++ P P I + P + + G+ F C+A + M ++ + + ++ Sbjct: 482 SIFAVSPDGFVCDDFPKPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNELL 541 Query: 336 FPGMSRDKYHATA----VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF-VRGKLTVT 390 + H A V + T+L + + + S C N+ GSS+ V+ KLTV Sbjct: 542 HDAEMENYAHLRAQGGEVMEYTTILRLREVEFA-SEGKYQCVISNHFGSSYSVKAKLTVN 600 Query: 391 SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG----EALIQNHRRNV 446 P T P + T+ +MA C A+ P P IAW +G A + + Sbjct: 601 M-----LPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVM 655 Query: 447 TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 D + D+ D G Y+C A + G + L V Sbjct: 656 PEDDVFFIVDVKIEDIGVYSCTAQNSAGSISANATLTV 693 Score = 56.0 bits (129), Expect = 6e-06 Identities = 39/95 (41%), Positives = 47/95 (49%), Gaps = 6/95 (6%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFF 68 E P + LD TV + + A L C AGGSP P + W K LVV++ H A G Sbjct: 695 ETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERH---FFAAGNQL 751 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103 L V SDAG Y CE +N+ GT R N L V Sbjct: 752 LIIVDSDV-SDAGKYTCEMSNTLGTERG-NVRLSV 784 >UniRef50_Q8UVD6 Cluster: Brother of CDO; n=2; Danio rerio|Rep: Brother of CDO - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 1032 Score = 106 bits (254), Expect = 4e-21 Identities = 89/344 (25%), Positives = 146/344 (42%), Gaps = 29/344 (8%) Query: 1 MSDDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGG--VLVVSDTH 57 + D + + P E+P V TL C A P+ I W+ G + D Sbjct: 29 LQDSNAVTDDVPVFTEEPFSVVQKLGGSVTLRCSA--LPNHVNISWHLNGRELPAGGDEE 86 Query: 58 RSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK 117 +L G ++ + + G Y C AT S G+ S A + A LR+ EP+ + Sbjct: 87 LGVLVRPGSLYIPSL---TNLTVGRYQCVATTSVGSCASVPANVTAAKLRD---FEPDDQ 140 Query: 118 QSAQ---GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTD 174 Q + G+T V+EC P P+ V + Q L ++ GNL I +A + D Sbjct: 141 QEIEVDEGNTAVIECHLPESQPKAQVRYSVK-QEWLETSKGNYLIMPSGNLQIANATRDD 199 Query: 175 AGRYQCIARNAAGTR-ESAIATLKIHIK------PYLITGP--EDVVAQTGSSVTFQCRV 225 G Y C A N +++ +T ++ I+ +I P ++ G + +C Sbjct: 200 EGPYICAAYNPVTQEIKTSTSTDRLRIRRSTSEAARIIYPPASRSIMVNKGQRLVLECVA 259 Query: 226 GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASG 285 G P P V W + G + L +L +D +D G Y C A+N +G+ S++ Sbjct: 260 SGIPTPQVTWAKD-GLDLRNHNNTRFLLS-NLLIDAASESDSGTYVCLADNGIGSTSSAQ 317 Query: 286 YL---TVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326 L V++PP + + +V G+ RF+C G+P PT+ W Sbjct: 318 VLYDVQVFEPPQVRVELQQQDVAWGDTVRFSCQVRGKPAPTVVW 361 Score = 91.1 bits (216), Expect = 2e-16 Identities = 88/288 (30%), Positives = 132/288 (45%), Gaps = 23/288 (7%) Query: 20 DVTVARHQPATLNCRAGGS-PSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77 ++ V A + C S P +R+ K L S + I+P+G L AT Sbjct: 142 EIEVDEGNTAVIECHLPESQPKAQVRYSVKQEWLETSKGNYLIMPSGNLQIANATR---- 197 Query: 78 SDAGVYWCEATNSYGTA-RSRNATLHVAVLR---EEFRL-EPESKQSA---QGDTVVLEC 129 D G Y C A N ++ +T + + R E R+ P + +S +G +VLEC Sbjct: 198 DDEGPYICAAYNPVTQEIKTSTSTDRLRIRRSTSEAARIIYPPASRSIMVNKGQRLVLEC 257 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189 + G P P V W K+G L ++R L NL+I A ++D+G Y C+A N G+ Sbjct: 258 VAS-GIPTPQVTWAKDGLDLRNHNNTRFLL---SNLLIDAASESDSGTYVCLADNGIGST 313 Query: 190 ESAIATLKIHI--KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247 SA + + P + + G +V F C+V G P P V+W +A + P Sbjct: 314 SSAQVLYDVQVFEPPQVRVELQQQDVAWGDTVRFSCQVRGKPAPTVVWLHNAQPLS-PSP 372 Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPS 294 R +V LR+ NV D+G Y C AEN VG + +A+ LT+ PS Sbjct: 373 RHRV-SAQVLRVLNVGPQDDGMYQCMAENGVGSSQAATRLLTLPTVPS 419 Score = 79.4 bits (187), Expect = 6e-13 Identities = 90/378 (23%), Positives = 142/378 (37%), Gaps = 29/378 (7%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH-LVDGGNLVIQ 168 F EP S G +V L C N+ W NG+ L GD + LV G+L I Sbjct: 42 FTEEPFSVVQKLGGSVTLRCSALPN--HVNISWHLNGRELPAGGDEELGVLVRPGSLYIP 99 Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVG- 226 GRYQC+A + G+ S A + ++ + +++ G++ +C + Sbjct: 100 SLTNLTVGRYQCVATTSVGSCASVPANVTAAKLRDFEPDDQQEIEVDEGNTAVIECHLPE 159 Query: 227 GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY 286 P V + G ++ G+L++ N DEG Y C A N V + Sbjct: 160 SQPKAQVRYSVKQEWLETSKGNYLIMPSGNLQIANATRDDEGPYICAAYNPVTQEIKTST 219 Query: 287 LT--------VYDPPSINLSP--NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF 336 T + I P S+ V G C A+G P P + W+ + Sbjct: 220 STDRLRIRRSTSEAARIIYPPASRSIMVNKGQRLVLECVASGIPTPQVTWAKD------- 272 Query: 337 PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP 396 G+ ++ T ++ L I+ ++DS T VC A N GS+ L + Sbjct: 273 -GLDLRNHNNTRFL--LSNLLIDAASESDS-GTYVCLADNGIGSTSSAQVLYDVQVFE-- 326 Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKD 456 PP + Q + F C P P + W + L + R V+ VL + Sbjct: 327 PPQVRVELQQQDVAWGDTVRFSCQVRGKPAPTVVWLHNAQPLSPSPRHRVSAQVLRVL-N 385 Query: 457 LDKSDSGTYTCVASSRHG 474 + D G Y C+A + G Sbjct: 386 VGPQDDGMYQCMAENGVG 403 Score = 39.5 bits (88), Expect = 0.55 Identities = 55/227 (24%), Positives = 88/227 (38%), Gaps = 25/227 (11%) Query: 502 SLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV 561 S P P +P T+TS ++W G+ ++ F E + S W Sbjct: 577 SPPEAPDRPTVSMATETSAYVTWIPRGN------RGFPIQSFRVE---HKKLRKGSGDWE 627 Query: 562 VIARRVHQTHYVVK--SLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTG 619 V + + V+ L G +Y F V N G S PS S + TV G+G Sbjct: 628 VAVNNIPPSRLSVEVTGLEKGTSYKFRVLAVNVLGASPPSAPSKAYTV--------VGSG 679 Query: 620 VSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYE 679 N +T + E I T I +K + LN + G +I++RP D+ + + Sbjct: 680 PPNRRPIDGPYITYN--EAINETTI---ILKWTYTPLNNTPIYGFYIFYRPTDSDN-DSD 733 Query: 680 MKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQT 726 K + D IT L+ T Y+ + F + E + N + +T Sbjct: 734 YKKDVVEGDRYWHSITDLQPETAYDIKMQCFNEGGESEFGNVVILET 780 >UniRef50_Q4RRS5 Cluster: Chromosome 16 SCAF15002, whole genome shotgun sequence; n=4; Euteleostomi|Rep: Chromosome 16 SCAF15002, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1278 Score = 106 bits (254), Expect = 4e-21 Identities = 134/522 (25%), Positives = 204/522 (39%), Gaps = 60/522 (11%) Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT 173 P+ ++ +G + VL C +G+P+P + W + G+ L + + V G+L I + Sbjct: 151 PQYVEAKEGGSTVLSC-SAQGNPKPMISWLREGEELATNAKYTVRKVHDGSLTILGITRD 209 Query: 174 DAGRYQCIARNAAG-----TR---ESAIATLKIHIK-----PYLITGPEDVVAQTGSSVT 220 D G Y C A + G TR + + +H K PY+++ PE+V + Sbjct: 210 DRGAYTCRAYSDQGEVLHTTRLLVQGIAISPALHYKSTLWPPYIVSPPENVTVNISQNAL 269 Query: 221 FQCRV---GGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAEN 276 F C+ G+ W L RV++L DG+L + V D G+Y+C N Sbjct: 270 FTCQAEAYPGNLTYTWFWEEDNVYFKNDLKLRVRILIDGTLIIFRVKPEDAGKYTCTPSN 329 Query: 277 SVG-AVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPT-MFWSVEGNRTI 334 S+G + SAS +LTV P + P + V C P T + W +G Sbjct: 330 SLGISPSASAHLTVQYPARVINMPPVIYVPRKLPGIIRCPVDANPPVTSVKWEKDG---- 385 Query: 335 IFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394 +P + +KY ++ ++ T+ DS T C N G+ + + T+ D Sbjct: 386 -YP-LRVEKYPGWSLTPDGSIRVAEATE--DSLGTYTCVPYNALGTMGMSPQATLVLKD- 440 Query: 395 RPPPIITNGPSNQ-TLPIKSMAVFPCTAICTPE-PIIAWYFEGEALIQNHRRNVTNDGTL 452 PP P + V PC A P+ P I W G+ H NV G+L Sbjct: 441 --PPYFNVRPGGEYRQEAGRELVIPCAASGDPDIPTITWRKVGKPSKSKH--NVLPSGSL 496 Query: 453 VLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPIT 512 L K D G + CVA++ S +LV I + H ++ LP Sbjct: 497 QFLSLSKEDHGEWECVATNVVTSITASTRILV---IGTSPH--APGNIHVLP-------- 543 Query: 513 HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHY 572 + TS +SW G S+ T G P + W + QT Sbjct: 544 ---SMTSANVSWEPGYDGGFEQTFSVWYGPVSKRTDFG---PHD---WHSMPVSGAQTWL 594 Query: 573 VVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSL 614 VV L PG Y F V +N G P S+ VTV + L Sbjct: 595 VVPGLEPGTEYQFSVLAQNK---LGTGPFSEVVTVNTTGSPL 633 Score = 96.7 bits (230), Expect = 3e-18 Identities = 82/286 (28%), Positives = 118/286 (41%), Gaps = 16/286 (5%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIR---WYKGGVLVVSDTHRS--ILPAGGL 66 PYI+ P +VTV Q A C+A P W + V +D IL G L Sbjct: 251 PYIVSPPENVTVNISQNALFTCQAEAYPGNLTYTWFWEEDNVYFKNDLKLRVRILIDGTL 310 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126 R DAG Y C +NS G + S +A L V + P + ++ Sbjct: 311 IIFRVKP----EDAGKYTCTPSNSLGISPSASAHLTVQYPARVINMPPVIYVPRKLPGII 366 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186 C P +V W+K+G L + L G++ + +A + G Y C+ NA Sbjct: 367 -RCPVDANPPVTSVKWEKDGYPLRVEKYPGWSLTPDGSIRVAEATEDSLGTYTCVPYNAL 425 Query: 187 GTR-ESAIATLKIHIKPYLITGPEDVVAQ-TGSSVTFQCRVGGDP-LPDVLWRRSAGGGN 243 GT S ATL + PY P Q G + C GDP +P + WR+ G Sbjct: 426 GTMGMSPQATLVLKDPPYFNVRPGGEYRQEAGRELVIPCAASGDPDIPTITWRKV---GK 482 Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 + VL GSL+ ++ D GE+ C A N V +++AS + V Sbjct: 483 PSKSKHNVLPSGSLQFLSLSKEDHGEWECVATNVVTSITASTRILV 528 Score = 69.3 bits (162), Expect = 6e-10 Identities = 98/401 (24%), Positives = 149/401 (37%), Gaps = 55/401 (13%) Query: 111 RLEPESKQSAQGDTVVLEC--LPPRGSPEPN--VYWKKNGQTLLF-------------DG 153 R EP + G++V+L C PP +P V W K G + F + Sbjct: 32 REEPRFVTARAGESVILGCDVSPPLDGQQPPYVVEWFKFGVPIPFFINFRFYPPHVDPEY 91 Query: 154 DSRMHLVDGGNLVIQDARQTDAGRYQC----IARNAAGTRESAIATLKIHIKP-YLITGP 208 R L +L I R D G Y+C + + + L ++ P + T P Sbjct: 92 TGRASLHGKASLQIDPVRSEDQGWYECRVLMLEQQYDTFHNGSWVHLTVNAPPSFTATPP 151 Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDGSLRLDNVILADE 267 + V A+ G S C G+P P + W R V+ + DGSL + + D Sbjct: 152 QYVEAKEGGSTVLSCSAQGNPKPMISWLREGEELATNAKYTVRKVHDGSLTILGITRDDR 211 Query: 268 GEYSCEAENSVGAV--------------SASGYLTVYDPPSINLSPNSVNVESGNVARFT 313 G Y+C A + G V A Y + PP I P +V V A FT Sbjct: 212 GAYTCRAYSDQGEVLHTTRLLVQGIAISPALHYKSTLWPPYIVSPPENVTVNISQNALFT 271 Query: 314 CTATGRP-EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372 C A P T W E + + K + DG ++ K + C Sbjct: 272 CQAEAYPGNLTYTWFWEEDNVYFKNDL---KLRVRILIDGTLIIF---RVKPEDAGKYTC 325 Query: 373 SAVNYAG-SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI--I 429 + N G S LTV + P + N P +P K + C P P+ + Sbjct: 326 TPSNSLGISPSASAHLTV-----QYPARVINMPPVIYVPRKLPGIIRCPVDANP-PVTSV 379 Query: 430 AWYFEGEAL-IQNHRR-NVTNDGTLVLKDLDKSDSGTYTCV 468 W +G L ++ + ++T DG++ + + + GTYTCV Sbjct: 380 KWEKDGYPLRVEKYPGWSLTPDGSIRVAEATEDSLGTYTCV 420 Score = 60.1 bits (139), Expect = 4e-07 Identities = 37/128 (28%), Positives = 60/128 (46%), Gaps = 4/128 (3%) Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNV--TNDGTLV 453 PP P V C+A P+P+I+W EGE L N + V +DG+L Sbjct: 143 PPSFTATPPQYVEAKEGGSTVLSCSAQGNPKPMISWLREGEELATNAKYTVRKVHDGSLT 202 Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS-PINPNIHFFRAADVSSLPGPPTKPIT 512 + + + D G YTC A S G+ + + LLV I+P +H+ + PP + +T Sbjct: 203 ILGITRDDRGAYTCRAYSDQGEVLHTTRLLVQGIAISPALHYKSTLWPPYIVSPP-ENVT 261 Query: 513 HNVTDTSV 520 N++ ++ Sbjct: 262 VNISQNAL 269 >UniRef50_Q1ENI8 Cluster: Peroxidasin (Drosophila peroxidase) homolog protein 1; n=2; Caenorhabditis|Rep: Peroxidasin (Drosophila peroxidase) homolog protein 1 - Caenorhabditis elegans Length = 1285 Score = 106 bits (254), Expect = 4e-21 Identities = 63/183 (34%), Positives = 88/183 (48%), Gaps = 4/183 (2%) Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ 168 +F +P +G V + C G+P+P + W NG+ + ++ L L I Sbjct: 316 QFTYKPRDNSFREGSEVKVNC-EVMGNPKPTINWYHNGKRFISSRKRQLGL-SNNVLRIY 373 Query: 169 DARQTDAGRYQCIARNAAG-TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGG 227 + D+GRY C A N+ G R + L + P + GP+ V G SV F C+ G Sbjct: 374 PFLEEDSGRYTCEAVNSVGKVRHAFSLDLISSVPPNIYEGPQSVSQNLGGSVVFVCKANG 433 Query: 228 DPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGY 286 +P+PD W GR V DDG+ LR+ N+ DEG YSC A N VGA+SA Sbjct: 434 NPVPDYTWSFDGSTIGHIKGRFMVSDDGTELRISNIEKKDEGYYSCMAGNPVGAMSADAK 493 Query: 287 LTV 289 LTV Sbjct: 494 LTV 496 Score = 81.4 bits (192), Expect = 1e-13 Identities = 63/196 (32%), Positives = 85/196 (43%), Gaps = 10/196 (5%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDN 261 P P D + GS V C V G+P P + W + R L + LR+ Sbjct: 315 PQFTYKPRDNSFREGSEVKVNCEVMGNPKPTINWYHNGKRFISSRKRQLGLSNNVLRIYP 374 Query: 262 VILADEGEYSCEAENSVGAVSASGYLTVYD--PPSINLSPNSVNVESGNVARFTCTATGR 319 + D G Y+CEA NSVG V + L + PP+I P SV+ G F C A G Sbjct: 375 FLEEDSGRYTCEAVNSVGKVRHAFSLDLISSVPPNIYEGPQSVSQNLGGSVVFVCKANGN 434 Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379 P P WS +G+ TI G + ++ V D T L I++ +K D C A N G Sbjct: 435 PVPDYTWSFDGS-TI---GHIKGRF---MVSDDGTELRISNIEKKD-EGYYSCMAGNPVG 486 Query: 380 SSFVRGKLTVTSDDDR 395 + KLTV + R Sbjct: 487 AMSADAKLTVIGGETR 502 Score = 75.8 bits (178), Expect = 7e-12 Identities = 54/188 (28%), Positives = 80/188 (42%), Gaps = 5/188 (2%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 +P +P D + +NC G+P P I WY G +S R + + + LR Sbjct: 314 SPQFTYKPRDNSFREGSEVKVNCEVMGNPKPTINWYHNGKRFISSRKRQLGLSNNV--LR 371 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130 + + D+G Y CEA NS G R + ++ + P+S G +VV C Sbjct: 372 -IYPFLEEDSGRYTCEAVNSVGKVRHAFSLDLISSVPPNIYEGPQSVSQNLGGSVVFVC- 429 Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190 G+P P+ W +G T+ M DG L I + + D G Y C+A N G Sbjct: 430 KANGNPVPDYTWSFDGSTIGHIKGRFMVSDDGTELRISNIEKKDEGYYSCMAGNPVGAM- 488 Query: 191 SAIATLKI 198 SA A L + Sbjct: 489 SADAKLTV 496 Score = 64.1 bits (149), Expect = 2e-08 Identities = 53/184 (28%), Positives = 76/184 (41%), Gaps = 14/184 (7%) Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352 P P + G+ + C G P+PT+ W G R I SR + + Sbjct: 315 PQFTYKPRDNSFREGSEVKVNCEVMGNPKPTINWYHNGKRFI----SSRKRQLGLSN--- 367 Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412 VL I + DS C AVN G L + S PP I GP + + + Sbjct: 368 -NVLRIYPFLEEDS-GRYTCEAVNSVGKVRHAFSLDLISS---VPPNIYEGPQSVSQNLG 422 Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGT-LVLKDLDKSDSGTYTCVAS 470 VF C A P P W F+G + R V++DGT L + +++K D G Y+C+A Sbjct: 423 GSVVFVCKANGNPVPDYTWSFDGSTIGHIKGRFMVSDDGTELRISNIEKKDEGYYSCMAG 482 Query: 471 SRHG 474 + G Sbjct: 483 NPVG 486 Score = 46.8 bits (106), Expect = 0.004 Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 1/97 (1%) Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNV-TNDGTLVLKD 456 P T P + + S C + P+P I WY G+ I + +R + ++ L + Sbjct: 315 PQFTYKPRDNSFREGSEVKVNCEVMGNPKPTINWYHNGKRFISSRKRQLGLSNNVLRIYP 374 Query: 457 LDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIH 493 + DSG YTC A + GK + +L + S + PNI+ Sbjct: 375 FLEEDSGRYTCEAVNSVGKVRHAFSLDLISSVPPNIY 411 >UniRef50_UPI0000DB6DA9 Cluster: PREDICTED: similar to CG32387-PB, isoform B; n=1; Apis mellifera|Rep: PREDICTED: similar to CG32387-PB, isoform B - Apis mellifera Length = 829 Score = 105 bits (253), Expect = 6e-21 Identities = 89/339 (26%), Positives = 141/339 (41%), Gaps = 23/339 (6%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65 + S P I E+ + ++ + C A G+P+P RWY + + + G Sbjct: 249 IRSTMPPMINEKVVYMSARLKDTVVIPCVAYGNPTPTNRWYYNR----NQREEPVEDSSG 304 Query: 66 LFFLR----ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121 + +R G SD G Y C A+NS G + S L V+ ++P + Sbjct: 305 HYVVRDGSLIIQGVQESDGGSYMCTASNSEG-SESMEVRLTVSA-PLNVHVQPSIQTVDL 362 Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181 G L C G P+ +YW K+GQ L +R+ V + + + D G YQC Sbjct: 363 GKAAHLTC-SASGFPQAALYWLKDGQPL--RTGARIRAVSRERISVMSVAREDRGMYQCF 419 Query: 182 ARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA- 239 RN + IA L++ I P L+ + QTG SV+ +C G+P P + W Sbjct: 420 VRNEYEMAQ-GIAELRLGEIAPQLVYRFIEQTMQTGPSVSLKCSAAGNPTPQISWLLDGF 478 Query: 240 ---GGGNMPLGR-VKVLDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293 + +G+ V V D + + +V D GEY C A + G S S L +Y P Sbjct: 479 PLPQNDRLLIGQYVTVYGDVISHVNISSVKSEDGGEYECIASSRAGEASHSARLNIYGLP 538 Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332 + ++V+ +G C G P ++ W +G R Sbjct: 539 YVR-PMSTVSAVAGKQFHIKCPVAGYPIESIVWEKDGVR 576 Score = 103 bits (247), Expect = 3e-20 Identities = 123/521 (23%), Positives = 211/521 (40%), Gaps = 66/521 (12%) Query: 13 YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK--GGVLVVSDTHRSILPAGGLFF-- 68 ++ E P V ++C G+P+P + W GG + R +L G + F Sbjct: 27 FVSEPPSRVEFTNVNGGRVDCTVRGNPAPTVDWLAADGGSITSIPGIRHVLGNGTIHFPG 86 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATL--------------HV-------AVLR 107 A R +Y C A NS G SR+ T+ H+ ++ Sbjct: 87 FEAEVFRQDVHWAIYKCSAVNSVGAIVSRDVTVRAVCGLFVVFQAMAHIPRRPGVWGMVN 146 Query: 108 EEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVY--WKKNGQTLLFD---GDSRMHLVDG 162 + + E + G+ V++ C P + W + ++ GD + H++ Sbjct: 147 QRYDPEVQCPGGFLGNNVLMRCNVPSFVRDHVTITSWLQEPSFNIYPSTMGDGKYHMLSS 206 Query: 163 GNLVIQDARQTDAGR-YQCIARNAAGTRESAIATL--KIHIKPYLITGP----EDVV--- 212 G L+I + + DA R Y+C + T+E+ +++ ++ + T P E VV Sbjct: 207 GELMILNITREDAERTYRCRTHHRL-TQETVVSSNVGRLQLTEIRSTMPPMINEKVVYMS 265 Query: 213 AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK---VLDDGSLRLDNVILADEGE 269 A+ +V C G+P P W + P+ V+ DGSL + V +D G Sbjct: 266 ARLKDTVVIPCVAYGNPTPTNRWYYNRNQREEPVEDSSGHYVVRDGSLIIQGVQESDGGS 325 Query: 270 YSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVE 329 Y C A NS G+ S LTV P ++++ P+ V+ G A TC+A+G P+ ++W + Sbjct: 326 YMCTASNSEGSESMEVRLTVSAPLNVHVQPSIQTVDLGKAAHLTCSASGFPQAALYWLKD 385 Query: 330 GNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389 G P + + A + + ++V+++ + R C N +G + Sbjct: 386 GQ-----PLRTGARIRAVS-RERISVMSV----AREDRGMYQCFVRN--EYEMAQGIAEL 433 Query: 390 TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR----RN 445 + P + QT+ C+A P P I+W +G L QN R + Sbjct: 434 RLGEIAPQLVYRF--IEQTMQTGPSVSLKCSAAGNPTPQISWLLDGFPLPQNDRLLIGQY 491 Query: 446 VTNDGTLV----LKDLDKSDSGTYTCVASSRHGKYVWSGAL 482 VT G ++ + + D G Y C+ASSR G+ S L Sbjct: 492 VTVYGDVISHVNISSVKSEDGGEYECIASSRAGEASHSARL 532 Score = 96.7 bits (230), Expect = 3e-18 Identities = 97/420 (23%), Positives = 172/420 (40%), Gaps = 37/420 (8%) Query: 123 DTVVLECLPPRGSPEPNVYW--KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180 DTVV+ C+ G+P P W +N + + S ++V G+L+IQ +++D G Y C Sbjct: 270 DTVVIPCVA-YGNPTPTNRWYYNRNQREEPVEDSSGHYVVRDGSLIIQGVQESDGGSYMC 328 Query: 181 IARNAAGT-----RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235 A N+ G+ R + A L +H++P + T G + C G P + W Sbjct: 329 TASNSEGSESMEVRLTVSAPLNVHVQPSIQT------VDLGKAAHLTCSASGFPQAALYW 382 Query: 236 RRSAGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-PP 293 + G + G R++ + + + +V D G Y C N L + + P Sbjct: 383 LKD--GQPLRTGARIRAVSRERISVMSVAREDRGMYQCFVRNEYEMAQGIAELRLGEIAP 440 Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDK----YHATAV 349 + +++G C+A G P P + W ++G FP D+ + T Sbjct: 441 QLVYRFIEQTMQTGPSVSLKCSAAGNPTPQISWLLDG-----FPLPQNDRLLIGQYVTVY 495 Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409 D ++ + I+ K++ C A + AG + +L + P + + + Sbjct: 496 GDVISHVNISSV-KSEDGGEYECIASSRAGEASHSARLNIYGLPYVRPMSTVSAVAGKQF 554 Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDK-SDSGTYTCV 468 IK C P I W +G L N R+ V N G+L + + + +D GTYTC Sbjct: 555 HIK------CPVAGYPIESIVWEKDGVRLPTNMRQRVAN-GSLFIDTVQRAADQGTYTCT 607 Query: 469 ASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNN 528 A ++H + ++ V + P I F A ++ + D +T +W ++N Sbjct: 608 ARNKH-NFTSQRSVEVRVLVPPKITPFSFARDLNVGDRTSVQCVVVTGDLPLTFTWLKDN 666 Score = 83.8 bits (198), Expect = 3e-14 Identities = 84/320 (26%), Positives = 130/320 (40%), Gaps = 21/320 (6%) Query: 17 QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV 76 QP TV + A L C A G P A+ W K G + + + + + Sbjct: 354 QPSIQTVDLGKAAHLTCSASGFPQAALYWLKDGQPLRTGARIRAVSRERISVMSV----A 409 Query: 77 HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136 D G+Y C N Y A+ A L + + + + G +V L+C G+P Sbjct: 410 REDRGMYQCFVRNEYEMAQG-IAELRLGEIAPQLVYRFIEQTMQTGPSVSLKC-SAAGNP 467 Query: 137 EPNVYWKKNGQTLLFDGDSRM---HLVDGGNLV----IQDARQTDAGRYQCIARNAAGTR 189 P + W +G L D + ++ G+++ I + D G Y+CIA + AG Sbjct: 468 TPQISWLLDGFPLP-QNDRLLIGQYVTVYGDVISHVNISSVKSEDGGEYECIASSRAG-E 525 Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249 S A L I+ PY + V A G +C V G P+ ++W + G +P Sbjct: 526 ASHSARLNIYGLPY-VRPMSTVSAVAGKQFHIKCPVAGYPIESIVWEKD--GVRLPTNMR 582 Query: 250 KVLDDGSLRLDNV-ILADEGEYSCEAENSVGAVS-ASGYLTVYDPPSINLSPNSVNVESG 307 + + +GSL +D V AD+G Y+C A N S S + V PP I + ++ G Sbjct: 583 QRVANGSLFIDTVQRAADQGTYTCTARNKHNFTSQRSVEVRVLVPPKITPFSFARDLNVG 642 Query: 308 NVARFTC-TATGRPEPTMFW 326 + C TG T W Sbjct: 643 DRTSVQCVVVTGDLPLTFTW 662 Score = 63.7 bits (148), Expect = 3e-08 Identities = 65/279 (23%), Positives = 109/279 (39%), Gaps = 26/279 (9%) Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR- 384 W E + I M KYH + ++ +N T + D+ T C + V Sbjct: 183 WLQEPSFNIYPSTMGDGKYH---MLSSGELMILNIT-REDAERTYRCRTHHRLTQETVVS 238 Query: 385 ---GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG----EA 437 G+L +T PP+I + +K V PC A P P WY+ E Sbjct: 239 SNVGRLQLTEIRSTMPPMINEKVVYMSARLKDTVVIPCVAYGNPTPTNRWYYNRNQREEP 298 Query: 438 LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRA 497 + + V DG+L+++ + +SD G+Y C AS+ G L V +P+N ++ Sbjct: 299 VEDSSGHYVVRDGSLIIQGVQESDGGSYMCTASNSEGSESMEVRLTVSAPLNVHVQ---- 354 Query: 498 ADVSSLPGPPTKPITHNVTD-TSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556 + ++ +T + + L W K G G ++ SRE +S + R Sbjct: 355 PSIQTVDLGKAAHLTCSASGFPQAALYWL---KDGQPLRTGARIRAVSRERISVMSVARE 411 Query: 557 SRG-WVVIARRVHQTHYVVKSL-----IPGITYMFIVRT 589 RG + R ++ + L P + Y FI +T Sbjct: 412 DRGMYQCFVRNEYEMAQGIAELRLGEIAPQLVYRFIEQT 450 Score = 59.3 bits (137), Expect = 6e-07 Identities = 56/226 (24%), Positives = 93/226 (41%), Gaps = 12/226 (5%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 AP ++ + ++ T+ +L C A G+P+P I W G + + I ++ Sbjct: 439 APQLVYRFIEQTMQTGPSVSLKCSAAGNPTPQISWLLDGFPLPQNDRLLIGQYVTVYGDV 498 Query: 71 ATHGRVHS----DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTV 125 +H + S D G Y C A++ G A S +A L++ L + P S SA G Sbjct: 499 ISHVNISSVKSEDGGEYECIASSRAGEA-SHSARLNIYGLP---YVRPMSTVSAVAGKQF 554 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 ++C P G P ++ W+K+G L + R + +G + R D G Y C ARN Sbjct: 555 HIKC-PVAGYPIESIVWEKDGVRL--PTNMRQRVANGSLFIDTVQRAADQGTYTCTARNK 611 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231 +++ + P + G + QC V LP Sbjct: 612 HNFTSQRSVEVRVLVPPKITPFSFARDLNVGDRTSVQCVVVTGDLP 657 Score = 36.3 bits (80), Expect = 5.1 Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 6/91 (6%) Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW-SVEGNRTIIFPGMSRDKYHATAVF 350 P ++ P+ V + N R CT G P PT+ W + +G PG+ + T F Sbjct: 25 PSFVSEPPSRVEFTNVNGGRVDCTVRGNPAPTVDWLAADGGSITSIPGIRHVLGNGTIHF 84 Query: 351 DGVTVLTINDTDKNDSRNTIV-CSAVNYAGS 380 G + + D I CSAVN G+ Sbjct: 85 PGFEA----EVFRQDVHWAIYKCSAVNSVGA 111 >UniRef50_Q7Q3K8 Cluster: ENSANGP00000009916; n=4; Endopterygota|Rep: ENSANGP00000009916 - Anopheles gambiae str. PEST Length = 1448 Score = 104 bits (250), Expect = 1e-20 Identities = 132/531 (24%), Positives = 203/531 (38%), Gaps = 54/531 (10%) Query: 78 SDAGVYWCEATN-SYGTARSRNAT-LHVAV-LREEFRLEPESKQSAQ-GDTVVLECLPPR 133 SD G Y C+ + + +N T H+ V F + PE GD+++L C Sbjct: 221 SDQGWYECKVVFLNRPPKQHKNGTWFHLDVHAPPRFSVTPEDIIYVNLGDSIILNCQAD- 279 Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192 G+P P + W K+ + D S + + DG L I R D G Y CIARN G + S Sbjct: 280 GTPTPEILWYKDANPV--DPSSTVGIFNDGTELRISTIRHEDIGDYTCIARNGEG-QVSH 336 Query: 193 IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP-LPDVLWRRSAGGGNMPLG---R 248 A + I ++ P + G V F C P V W R R Sbjct: 337 TARVIIAGGAVIMVPPTNQTKLEGEKVQFTCEAKAMPGNVTVRWFREGSPVREVAALETR 396 Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAV-SASGYLTVYDPPSINLSPNSVNVESG 307 V + DGSL ++ V D G+Y+CE N +G SAS YL + P + +P + Sbjct: 397 VTIRKDGSLIINPVSADDSGQYTCEVSNGIGEPQSASAYLNIEYPAKVTFTPTIQYLPFR 456 Query: 308 NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367 C P P + + ++ ++ P ++D + + ++L + R Sbjct: 457 LAGVVQCYIKANP-PLQYVTWTKDKRLLEPYQTKD----IVIMNNGSLLFTRVNQNHQGR 511 Query: 368 NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN-QTLPIKSMAVFPCTAI---C 423 T C+ N G+ G + V R PP T P + C A Sbjct: 512 YT--CTPYNAQGTQGSSGHMEVLV---RKPPAFTVEPDPLYQRKVGESVEMHCDAQEAEG 566 Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483 T +P I W +Q +R + N G + +++L +SD G Y CVAS+ V + L+ Sbjct: 567 TSKPNIQWQRRDGQPLQKNRVRI-NSGNITIENLRRSDFGYYQCVASNEVATIVSATQLV 625 Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543 ++ + P P ++ + T+ SVTLSW G Y + Sbjct: 626 IE---------------GTQPHAPYN-LSGSATEFSVTLSWMPGYSGGPDYKQDYTIWYR 669 Query: 544 SRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHG 594 + P G T + L PG TY F V +N+ G Sbjct: 670 EAGVSEWSTIPVTPSG---------STQVTINRLSPGTTYEFQVIGKNALG 711 Score = 95.5 bits (227), Expect = 8e-18 Identities = 83/332 (25%), Positives = 138/332 (41%), Gaps = 23/332 (6%) Query: 164 NLVIQDARQTDAGRYQC----IARNAAGTRESAIATLKIHIKPYLITGPEDVV-AQTGSS 218 +L + D R++D G Y+C + R + L +H P PED++ G S Sbjct: 212 SLNLTDIRESDQGWYECKVVFLNRPPKQHKNGTWFHLDVHAPPRFSVTPEDIIYVNLGDS 271 Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENS 277 + C+ G P P++LW + A + P V + +DG+ LR+ + D G+Y+C A N Sbjct: 272 IILNCQADGTPTPEILWYKDANPVD-PSSTVGIFNDGTELRISTIRHEDIGDYTCIARNG 330 Query: 278 VGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP-EPTMFWSVEGNRTIIF 336 G VS + + + I + P + G +FTC A P T+ W EG+ Sbjct: 331 EGQVSHTARVIIAGGAVIMVPPTNQTKLEGEKVQFTCEAKAMPGNVTVRWFREGSPVREV 390 Query: 337 PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGS-SFVRGKLTVTSDDDR 395 + + T DG L IN +DS C N G L + Sbjct: 391 AAL---ETRVTIRKDG--SLIINPVSADDS-GQYTCEVSNGIGEPQSASAYLNI-----E 439 Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN---VTNDGTL 452 P +T P+ Q LP + V C P + + + L++ ++ + N+G+L Sbjct: 440 YPAKVTFTPTIQYLPFRLAGVVQCYIKANPPLQYVTWTKDKRLLEPYQTKDIVIMNNGSL 499 Query: 453 VLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 + ++++ G YTC + G SG + V Sbjct: 500 LFTRVNQNHQGRYTCTPYNAQGTQGSSGHMEV 531 Score = 81.8 bits (193), Expect = 1e-13 Identities = 78/306 (25%), Positives = 124/306 (40%), Gaps = 15/306 (4%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 LNC+A G+P+P I WYK V + I G LR + R H D G Y C A N Sbjct: 274 LNCQADGTPTPEILWYKDANPVDPSSTVGIFNDG--TELRISTIR-HEDIGDYTCIARNG 330 Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL- 149 G S A + +A + P ++ +G+ V C V W + G + Sbjct: 331 EGQV-SHTARVIIAG-GAVIMVPPTNQTKLEGEKVQFTCEAKAMPGNVTVRWFREGSPVR 388 Query: 150 -LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208 + ++R+ + G+L+I D+G+Y C N G +SA A L I + P Sbjct: 389 EVAALETRVTIRKDGSLIINPVSADDSGQYTCEVSNGIGEPQSASAYLNIEYPAKVTFTP 448 Query: 209 EDVVAQTGSSVTFQCRV-GGDPLPDVLWRRSAG-GGNMPLGRVKVLDDGSLRLDNVILAD 266 + QC + PL V W + + ++++GSL V Sbjct: 449 TIQYLPFRLAGVVQCYIKANPPLQYVTWTKDKRLLEPYQTKDIVIMNNGSLLFTRVNQNH 508 Query: 267 EGEYSCEAENSVGAVSASGYLTVY--DPPSINLSPNSV-NVESGNVARFTC---TATGRP 320 +G Y+C N+ G +SG++ V PP+ + P+ + + G C A G Sbjct: 509 QGRYTCTPYNAQGTQGSSGHMEVLVRKPPAFTVEPDPLYQRKVGESVEMHCDAQEAEGTS 568 Query: 321 EPTMFW 326 +P + W Sbjct: 569 KPNIQW 574 Score = 58.0 bits (134), Expect = 1e-06 Identities = 65/244 (26%), Positives = 106/244 (43%), Gaps = 29/244 (11%) Query: 60 ILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESK- 117 I+ G L F R G Y C N+ GT S + + V V + F +EP+ Sbjct: 493 IMNNGSLLFTRVNQNH----QGRYTCTPYNAQGTQGS-SGHMEVLVRKPPAFTVEPDPLY 547 Query: 118 QSAQGDTVVLEC--LPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTD 174 Q G++V + C G+ +PN+ W +++GQ L +R+ ++ GN+ I++ R++D Sbjct: 548 QRKVGESVEMHCDAQEAEGTSKPNIQWQRRDGQPLQ---KNRVR-INSGNITIENLRRSD 603 Query: 175 AGRYQCIARNAAGTRESA----IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPL 230 G YQC+A N T SA I + H PY ++G + T SVT G Sbjct: 604 FGYYQCVASNEVATIVSATQLVIEGTQPH-APYNLSG-----SATEFSVTLSWMPGYSGG 657 Query: 231 PD-----VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASG 285 PD +W R AG V + ++ + E+ +N++G S Sbjct: 658 PDYKQDYTIWYREAGVSEWSTIPVTPSGSTQVTINRLSPGTTYEFQVIGKNALGDGMMSK 717 Query: 286 YLTV 289 +T+ Sbjct: 718 VITI 721 >UniRef50_A7TCD9 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 303 Score = 104 bits (250), Expect = 1e-20 Identities = 78/219 (35%), Positives = 105/219 (47%), Gaps = 22/219 (10%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 ++T P TL C+A G P P +RW KGG +VS H I+ G LF +AT G D Sbjct: 97 NLTAFEKAPVTLTCKATGLPLPTVRWIKGGRQLVSKGH-EIVAGGRLFLGKATLG----D 151 Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ--SAQGDTVVLECLPPRGSPE 137 +G Y C AT+ G S + L + VLR + K + G+TV L C G P Sbjct: 152 SGEYECTATSPLGYV-SAKSNLEIKVLRRDKISTDLGKNVTTLSGNTVSLLC-NATGVPS 209 Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197 P + W K+G+TL + H V L + +D+G YQC ARN G ++ Sbjct: 210 PKLSWYKDGETL-----NISHAV----LTLPTLSPSDSGLYQCEARNLKGIDDADSYLTN 260 Query: 198 IHIKPYLITG-PEDVVAQTGSSVTFQCRVGGDPLPDVLW 235 I Y++TG DVV S+V C V G PLP + W Sbjct: 261 I---AYIVTGIGSDVVTLLSSNVEVTCPVRGFPLPSITW 296 Score = 91.9 bits (218), Expect = 1e-16 Identities = 91/311 (29%), Positives = 129/311 (41%), Gaps = 28/311 (9%) Query: 30 TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH-SDAGVYWCEAT 88 T+NC G P P++ W V L A + R T ++ SD+GVY C A Sbjct: 8 TINCPTEGLPRPSVTW---SVTRTQAPGVEGLQAVPIVTSRLTVAKLQLSDSGVYTCTAR 64 Query: 89 NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT------VVLECLPPRGSPEPNVYW 142 N G + T V V + LEP S T V L C G P P V W Sbjct: 65 NLKGNDTMTSVTSIVPVEALK-NLEPVSVLIGANLTAFEKAPVTLTC-KATGLPLPTVRW 122 Query: 143 KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI-- 200 K G+ L+ G +V GG L + A D+G Y+C A + G SA + L+I + Sbjct: 123 IKGGRQLVSKGHE---IVAGGRLFLGKATLGDSGEYECTATSPLGY-VSAKSNLEIKVLR 178 Query: 201 KPYLITG-PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL 259 + + T ++V +G++V+ C G P P + W + G + L L Sbjct: 179 RDKISTDLGKNVTTLSGNTVSLLCNATGVPSPKLSWYKD--------GETLNISHAVLTL 230 Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGR 319 + +D G Y CEA N G A YLT + + V + S NV TC G Sbjct: 231 PTLSPSDSGLYQCEARNLKGIDDADSYLTNIAYIVTGIGSDVVTLLSSNV-EVTCPVRGF 289 Query: 320 PEPTMFWSVEG 330 P P++ W +G Sbjct: 290 PLPSITWLKDG 300 Score = 87.8 bits (208), Expect = 2e-15 Identities = 66/220 (30%), Positives = 98/220 (44%), Gaps = 16/220 (7%) Query: 122 GDTVVLECLPPRGSPEPNVYWK-KNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180 G + + C P G P P+V W Q +G + +V L + + +D+G Y C Sbjct: 4 GSALTINC-PTEGLPRPSVTWSVTRTQAPGVEGLQAVPIVTS-RLTVAKLQLSDSGVYTC 61 Query: 181 IARNAAG--TRESAIATLKI----HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL 234 ARN G T S + + + +++P + ++ A + VT C+ G PLP V Sbjct: 62 TARNLKGNDTMTSVTSIVPVEALKNLEPVSVLIGANLTAFEKAPVTLTCKATGLPLPTVR 121 Query: 235 WRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV----Y 290 W + GG + +++ G L L L D GEY C A + +G VSA L + Sbjct: 122 WIK--GGRQLVSKGHEIVAGGRLFLGKATLGDSGEYECTATSPLGYVSAKSNLEIKVLRR 179 Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330 D S +L N V SGN C ATG P P + W +G Sbjct: 180 DKISTDLGKN-VTTLSGNTVSLLCNATGVPSPKLSWYKDG 218 Score = 74.5 bits (175), Expect = 2e-11 Identities = 75/268 (27%), Positives = 114/268 (42%), Gaps = 30/268 (11%) Query: 216 GSSVTFQCRVGGDPLPDVLWR--RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCE 273 GS++T C G P P V W R+ G L V ++ L + + L+D G Y+C Sbjct: 4 GSALTINCPTEGLPRPSVTWSVTRTQAPGVEGLQAVPIVTS-RLTVAKLQLSDSGVYTCT 62 Query: 274 AENSVGAVSASGYLTVYDPPSI-NLSPNSVNVESGNVA------RFTCTATGRPEPTMFW 326 A N G + + ++ ++ NL P SV + + A TC ATG P PT+ W Sbjct: 63 ARNLKGNDTMTSVTSIVPVEALKNLEPVSVLIGANLTAFEKAPVTLTCKATGLPLPTVRW 122 Query: 327 SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386 ++G R ++ G + +F G T+ D+ + + C+A + G +V K Sbjct: 123 -IKGGRQLVSKG--HEIVAGGRLFLGKA--TLGDSGEYE------CTATSPLG--YVSAK 169 Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNV 446 + R I T+ N T + C A P P ++WY +GE L +H Sbjct: 170 SNLEIKVLRRDKISTDLGKNVTTLSGNTVSLLCNATGVPSPKLSWYKDGETLNISH---- 225 Query: 447 TNDGTLVLKDLDKSDSGTYTCVASSRHG 474 L L L SDSG Y C A + G Sbjct: 226 ---AVLTLPTLSPSDSGLYQCEARNLKG 250 Score = 46.8 bits (106), Expect = 0.004 Identities = 51/226 (22%), Positives = 83/226 (36%), Gaps = 11/226 (4%) Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365 +G+ C G P P++ WSV + PG+ + A + + LT+ +D Sbjct: 3 AGSALTINCPTEGLPRPSVTWSVTRTQA---PGV--EGLQAVPIV--TSRLTVAKLQLSD 55 Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDD--DRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423 S C+A N G+ + ++ + P+ +N T K+ C A Sbjct: 56 S-GVYTCTARNLKGNDTMTSVTSIVPVEALKNLEPVSVLIGANLTAFEKAPVTLTCKATG 114 Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483 P P + W G L+ V G L L DSG Y C A+S G L Sbjct: 115 LPLPTVRWIKGGRQLVSKGHEIVAG-GRLFLGKATLGDSGEYECTATSPLGYVSAKSNLE 173 Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529 + I +V++L G + + S LSW ++ + Sbjct: 174 IKVLRRDKISTDLGKNVTTLSGNTVSLLCNATGVPSPKLSWYKDGE 219 Score = 46.8 bits (106), Expect = 0.004 Identities = 38/130 (29%), Positives = 59/130 (45%), Gaps = 15/130 (11%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 +VT +L C A G PSP + WYK G + + ++L L SD Sbjct: 189 NVTTLSGNTVSLLCNATGVPSPKLSWYKDGETL--NISHAVLTLPTLS---------PSD 237 Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139 +G+Y CEA N G + + ++A + + + S+ V + C P RG P P+ Sbjct: 238 SGLYQCEARNLKGIDDADSYLTNIAYIVTGIGSDVVTLLSSN---VEVTC-PVRGFPLPS 293 Query: 140 VYWKKNGQTL 149 + W K+GQ L Sbjct: 294 ITWLKDGQPL 303 >UniRef50_UPI00015B5ECA Cluster: PREDICTED: similar to rCG56583; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to rCG56583 - Nasonia vitripennis Length = 1130 Score = 103 bits (248), Expect = 2e-20 Identities = 96/347 (27%), Positives = 141/347 (40%), Gaps = 27/347 (7%) Query: 71 ATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 AT +S Y C A SYG + RS + A L FR PE +G+ L C Sbjct: 115 ATVSSRNSQRNEYRCVARTSYGASLRSAPTNILYAELAHTFRESPEDSTVREGEVARLSC 174 Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMH-LVDGGNLVIQDARQTDAGRYQCIARN---- 184 L PN+ W +G+ + D + + + G L I+ + +DAG Y+C+A N Sbjct: 175 LIDSVPFPPNITWLHDGELVPTDHNKTKYAFIPPGVLYIRATKLSDAGSYRCVAANDFIN 234 Query: 185 -AAGTRESAIATLKIHIKPYLITG----PEDVVAQT---GSSVTFQCRVGGDPLPDVLWR 236 ++E+ + + H + P+ + T GS + C G P P W Sbjct: 235 ATKKSKEAKLTVISRHESKESSSSVSLFPQTSYSHTPLIGSHLKLACAASGYPPPKTSWT 294 Query: 237 RSAGGGNMPLGRVKVLDDGS-----LRLDNVILADEGEYSCEAENSVGAVSASGYLTV-- 289 A + + + L + S L L N+ D G Y C N + LTV Sbjct: 295 FVAQYADTETAKHRALLNSSSGLAVLELKNITTTDAGTYVCSVNNITSNATEIQNLTVEV 354 Query: 290 YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349 Y PP+ P + +G ARF C A G P P ++W ++ I G R Y Sbjct: 355 YVPPTFVKKPTNQACPNGRTARFECQARGFPTPRIYW-LKNAADITING-RRTVYEKE-- 410 Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP 396 F+ V L I+ T +DS C AVN AG G+L V + + P Sbjct: 411 FNKVE-LAISATVPSDS-GIYQCVAVNAAGEVSAAGRLQVNTSRNSP 455 Score = 101 bits (242), Expect = 1e-19 Identities = 156/675 (23%), Positives = 252/675 (37%), Gaps = 86/675 (12%) Query: 163 GNLVIQDARQTDAGRYQCIARNAAGT--RESAIATLKIHIKPYLITGPEDVVAQTGSSVT 220 GN + +R + Y+C+AR + G R + L + PED + G Sbjct: 113 GNATVS-SRNSQRNEYRCVARTSYGASLRSAPTNILYAELAHTFRESPEDSTVREGEVAR 171 Query: 221 FQCRVGGDPLP-DVLWRRSAGGGNMPLGRVKV----LDDGSLRLDNVILADEGEYSCEAE 275 C + P P ++ W G +P K + G L + L+D G Y C A Sbjct: 172 LSCLIDSVPFPPNITWLHD--GELVPTDHNKTKYAFIPPGVLYIRATKLSDAGSYRCVAA 229 Query: 276 NS-VGAVSAS--GYLTVYD-------PPSINLSPNSVNVES---GNVARFTCTATGRPEP 322 N + A S LTV S++L P + + G+ + C A+G P P Sbjct: 230 NDFINATKKSKEAKLTVISRHESKESSSSVSLFPQTSYSHTPLIGSHLKLACAASGYPPP 289 Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382 W+ R ++++ G+ VL + + D+ T VCS N ++ Sbjct: 290 KTSWTFVAQYADTETAKHRALLNSSS---GLAVLELKNITTTDA-GTYVCSVNNITSNAT 345 Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH 442 LTV + PP P+NQ P A F C A P P I W + N Sbjct: 346 EIQNLTV---EVYVPPTFVKKPTNQACPNGRTARFECQARGFPTPRIYWLKNAADITING 402 Query: 443 RRNV----TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAA 498 RR V N L + SDSG Y CVA + G+ +G L V++ N Sbjct: 403 RRTVYEKEFNKVELAISATVPSDSGIYQCVAVNAAGEVSAAGRLQVNTSRNS-------- 454 Query: 499 DVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558 P PT + + +SW + ++I Y V R G Sbjct: 455 -----PAAPTSLKCEARSPVKIFISWEPPKFLPFTNI-AYTVHY--RPVEGGKEEVSPEP 506 Query: 559 GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGT 618 G V K L P Y F VR N+H GPS SD++T + Sbjct: 507 GNTTSVE-------VTKLLEPFTNYTFYVRLWNNH---GPSDQSDTITCSTNE------- 549 Query: 619 GVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEY 678 GV + I I+S + + W+ L +G+ ++ + Sbjct: 550 GVPKA------------APKISVDAINSTKLNVTWKPLTKKEAQGIVTEYKLEWRLFQHP 597 Query: 679 EMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPI-N 737 ++ V + +T + Y+ ++ K+ +NS+ +P + Sbjct: 598 SVRVRTLPATVEQYVLTDMIPGEPYDIRVLARTKQGWPNVNNSQFGWITVTMPQSNDLTQ 657 Query: 738 IEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIM 797 ++FILN+T + +KW+ ++ I +N + ++V++N T AT ++ Sbjct: 658 TQVFILNSTAIQVKWN-----VKAYSILHFNSWKLYCKNEDGVTIVSVNLT-KNATEYLL 711 Query: 798 TNLTSGVSYSVQIAA 812 TNL S +SYSV++ A Sbjct: 712 TNLESNISYSVELCA 726 Score = 96.3 bits (229), Expect = 4e-18 Identities = 88/314 (28%), Positives = 133/314 (42%), Gaps = 28/314 (8%) Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSD---THRSILPAGGLFFLRA 71 E P D TV + A L+C P P I W G LV +D T + +P G L+ +RA Sbjct: 157 ESPEDSTVREGEVARLSCLIDSVPFPPNITWLHDGELVPTDHNKTKYAFIPPGVLY-IRA 215 Query: 72 THGRVHSDAGVYWCEATNSY--GTARSRNATLHVAVLREE------FRLEPESKQSAQ-- 121 T SDAG Y C A N + T +S+ A L V E L P++ S Sbjct: 216 TK---LSDAGSYRCVAANDFINATKKSKEAKLTVISRHESKESSSSVSLFPQTSYSHTPL 272 Query: 122 -GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN----LVIQDARQTDAG 176 G + L C G P P W Q + L++ + L +++ TDAG Sbjct: 273 IGSHLKLACAAS-GYPPPKTSWTFVAQYADTETAKHRALLNSSSGLAVLELKNITTTDAG 331 Query: 177 RYQCIARN-AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235 Y C N + E T+++++ P + P + G + F+C+ G P P + W Sbjct: 332 TYVCSVNNITSNATEIQNLTVEVYVPPTFVKKPTNQACPNGRTARFECQARGFPTPRIYW 391 Query: 236 RRSAGGGNMPLGRV---KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292 ++A + R K + L + + +D G Y C A N+ G VSA+G L V Sbjct: 392 LKNAADITINGRRTVYEKEFNKVELAISATVPSDSGIYQCVAVNAAGEVSAAGRLQVNTS 451 Query: 293 PSINLSPNSVNVES 306 + +P S+ E+ Sbjct: 452 RNSPAAPTSLKCEA 465 Score = 44.4 bits (100), Expect = 0.019 Identities = 32/130 (24%), Positives = 51/130 (39%), Gaps = 2/130 (1%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P +++P + + A C+A G P+P I W K + + R++ A Sbjct: 358 PTFVKKPTNQACPNGRTARFECQARGFPTPRIYWLKNAADITINGRRTVYEKEFNKVELA 417 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT-VVLECL 130 V SD+G+Y C A N+ G S L V R K A+ + + Sbjct: 418 ISATVPSDSGIYQCVAVNAAGEV-SAAGRLQVNTSRNSPAAPTSLKCEARSPVKIFISWE 476 Query: 131 PPRGSPEPNV 140 PP+ P N+ Sbjct: 477 PPKFLPFTNI 486 >UniRef50_Q7SY58 Cluster: Muscle, skeletal, receptor tyrosine kinase; n=2; Danio rerio|Rep: Muscle, skeletal, receptor tyrosine kinase - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 351 Score = 103 bits (247), Expect = 3e-20 Identities = 61/203 (30%), Positives = 98/203 (48%), Gaps = 5/203 (2%) Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIA 194 P+ ++ W +N + + DSR + + G L+I + + +D+G Y CIA N G +S A Sbjct: 53 PQADIIWTRNNYPIRYY-DSRYVIQENGQMLIIPNVKDSDSGEYCCIANNGVGEAKSCGA 111 Query: 195 TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254 L++ +KP + P ++ S C G P P++ W + R+ +L+ Sbjct: 112 -LQLKMKPQIKRHPTNMTLILESKAVLPCLSLGYPKPEISWIKEDDLIKAN-NRIAILES 169 Query: 255 GSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313 GSL++ N+ D G+Y C A NS G A S + V P I P V+ G+ Sbjct: 170 GSLKITNIKKEDAGQYRCVARNSFGIAFSRPVTIEVQAPAKILKVPKEKRVQIGSEVTLE 229 Query: 314 CTATGRPEPTMFWSVEGNRTIIF 336 C ATG P P++ W GN I++ Sbjct: 230 CNATGNPIPSITWLENGNTVILY 252 Score = 95.1 bits (226), Expect = 1e-17 Identities = 57/207 (27%), Positives = 97/207 (46%), Gaps = 7/207 (3%) Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88 AT C P I W + + R ++ G + SD+G Y C A Sbjct: 43 ATFICEVDSYPQADIIWTRNNYPIRYYDSRYVIQENGQMLI--IPNVKDSDSGEYCCIAN 100 Query: 89 NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148 N G A+S A L + ++ + + P + VL CL G P+P + W K Sbjct: 101 NGVGEAKSCGA-LQLK-MKPQIKRHPTNMTLILESKAVLPCLS-LGYPKPEISWIKEDD- 156 Query: 149 LLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208 L ++R+ +++ G+L I + ++ DAG+Y+C+ARN+ G S T+++ ++ P Sbjct: 157 -LIKANNRIAILESGSLKITNIKKEDAGQYRCVARNSFGIAFSRPVTIEVQAPAKILKVP 215 Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLW 235 ++ Q GS VT +C G+P+P + W Sbjct: 216 KEKRVQIGSEVTLECNATGNPIPSITW 242 Score = 75.4 bits (177), Expect = 9e-12 Identities = 47/139 (33%), Positives = 72/139 (51%), Gaps = 6/139 (4%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I P ++T+ A L C + G P P I W K L+ ++ +IL +G L+ Sbjct: 118 PQIKRHPTNMTLILESKAVLPCLSLGYPKPEISWIKEDDLIKANNRIAILESGS---LKI 174 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131 T+ + DAG Y C A NS+G A SR T+ V + ++ P+ K+ G V LEC Sbjct: 175 TNIK-KEDAGQYRCVARNSFGIAFSRPVTIEVQAPAKILKV-PKEKRVQIGSEVTLEC-N 231 Query: 132 PRGSPEPNVYWKKNGQTLL 150 G+P P++ W +NG T++ Sbjct: 232 ATGNPIPSITWLENGNTVI 250 Score = 72.1 bits (169), Expect = 8e-11 Identities = 65/239 (27%), Positives = 99/239 (41%), Gaps = 15/239 (6%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLD 260 P + T E V + + TF C V P D++W R+ R + ++G L + Sbjct: 26 PRITTLLETVDSSLDHNATFICEVDSYPQADIIWTRNNYPIRYYDSRYVIQENGQMLIIP 85 Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320 NV +D GEY C A N VG + G L + P I P ++ + + A C + G P Sbjct: 86 NVKDSDSGEYCCIANNGVGEAKSCGALQLKMKPQIKRHPTNMTLILESKAVLPCLSLGYP 145 Query: 321 EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGS 380 +P + W E + + +R A+ + + L I + K D+ C A N G Sbjct: 146 KPEISWIKEDD---LIKANNR-----IAILESGS-LKITNIKKEDA-GQYRCVARNSFGI 195 Query: 381 SFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI 439 +F R VT + P I+ P + + I S C A P P I W G +I Sbjct: 196 AFSR---PVTIEVQAPAKIL-KVPKEKRVQIGSEVTLECNATGNPIPSITWLENGNTVI 250 Score = 64.9 bits (151), Expect = 1e-08 Identities = 48/182 (26%), Positives = 81/182 (44%), Gaps = 13/182 (7%) Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352 P I +V+ + A F C P+ + W+ +P D + + + Sbjct: 26 PRITTLLETVDSSLDHNATFICEVDSYPQADIIWTRNN-----YPIRYYDSRYV--IQEN 78 Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412 +L I + +DS C A N G + G L + + P I P+N TL ++ Sbjct: 79 GQMLIIPNVKDSDS-GEYCCIANNGVGEAKSCGALQL-----KMKPQIKRHPTNMTLILE 132 Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472 S AV PC ++ P+P I+W E + + N+R + G+L + ++ K D+G Y CVA + Sbjct: 133 SKAVLPCLSLGYPKPEISWIKEDDLIKANNRIAILESGSLKITNIKKEDAGQYRCVARNS 192 Query: 473 HG 474 G Sbjct: 193 FG 194 >UniRef50_A0JM54 Cluster: LOC100036605 protein; n=1; Xenopus tropicalis|Rep: LOC100036605 protein - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 1423 Score = 103 bits (246), Expect = 4e-20 Identities = 158/660 (23%), Positives = 257/660 (38%), Gaps = 69/660 (10%) Query: 79 DAGVYWCEAT---NSYGTARSRNAT-LHVAVLRE-EFRLEPESKQSAQ-GDTVVLECLPP 132 D G Y C +G +N T +H+ V FR P + + GDT+ L C+ Sbjct: 102 DQGWYECRVLFLDRHHGEEDFQNGTWVHLTVNSPPSFRETPPTYVEVRVGDTLTLTCVA- 160 Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192 G+P+P V WK++G TL GD G+L I + +AG Y C A + G Sbjct: 161 YGNPQPVVTWKRDGVTLE-SGDKVQ--ASNGSLSIVGVERGNAGVYTCHAFSDEGEVTHT 217 Query: 193 IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-----G 247 L + P ++ PE+ C+ P ++ + G N+ L Sbjct: 218 SRVL-VQGPPIIVVPPENTTVNVSQDAFLTCQAEAYPA-NLTYTWFQGSNNVFLLNRLQP 275 Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSPNSVNVES 306 RV++L DGS + V D G+Y+C N + + SAS YLTV P + P + Sbjct: 276 RVRILVDGSFLIQRVTPEDAGKYTCIPSNGMWKSPSASAYLTVLHPAYVTSMPAETYLPI 335 Query: 307 GNVARFTCTATGRPEPTMF-WSVEGNRTIIFPGMSRDKYHATAVF-DGVTVLTINDTDKN 364 G C P + W+ +G+ + DKY V DG V+ T + Sbjct: 336 GMRGVIKCPVRANPPLLLVNWTKDGH------ALELDKYPGWYVDEDGSLVIA---TGND 386 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP-IKSMAVFPCTAIC 423 D+ C+ N G+ V V + PP + PS + + V PC+A+ Sbjct: 387 DALGIYTCTPYNSYGTGGVSLPTEVILKE---PPSFIDVPSEEYFQDVGRELVIPCSAVG 443 Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483 P P+I W G L + + +LV + L K + G + C A++ A+ Sbjct: 444 DPPPLIRWSKLG--LPGKSAAQMDANSSLVFRPLTKEEHGIWECSATNHVATISARTAIY 501 Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543 V + + H ++S+L +SV +SW G + V+ Sbjct: 502 V---LGTSPH--AVTNISALS-----------LVSSVNVSWEP----GFDGGYFQRFSVW 541 Query: 544 SRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603 + R W+ ++ V TH +V +L Y F + ++N G P S+ Sbjct: 542 YAPLV--KRLTRGHHDWISLSAAVGATHLLVGNLQADTAYQFSILSQNK---LGTGPFSE 596 Query: 604 SVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMW--EILNFYYL 661 VT + + ++E +++ + E S+ + L W + + L Sbjct: 597 IVTATPLNFPVTTVPPPVPTSEPSDSLSPPRYLSANET----SEGVFLQWLPPLRSSLPL 652 Query: 662 EGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNS 721 G + FR D E ++I S + + L K T YEF L+ F + +PSNS Sbjct: 653 RGYGLEFR-RDEGAWELLDESIPESQ--TELVVRKLVKDTMYEFRLVAFAGDYISEPSNS 709 Score = 85.0 bits (201), Expect = 1e-14 Identities = 83/329 (25%), Positives = 134/329 (40%), Gaps = 21/329 (6%) Query: 156 RMHLVDGGNLVIQDARQTDAGRYQC---IARNAAGTRESAIAT---LKIHIKP-YLITGP 208 R + +G +L I+ R D G Y+C G + T L ++ P + T P Sbjct: 84 RTRIEEGASLHIESLRSEDQGWYECRVLFLDRHHGEEDFQNGTWVHLTVNSPPSFRETPP 143 Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268 V + G ++T C G+P P V W+R G + G +GSL + V + G Sbjct: 144 TYVEVRVGDTLTLTCVAYGNPQPVVTWKRD--GVTLESGDKVQASNGSLSIVGVERGNAG 201 Query: 269 EYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328 Y+C A + G V+ + + V PP I + P + V A TC A P + Sbjct: 202 VYTCHAFSDEGEVTHTSRVLVQGPPIIVVPPENTTVNVSQDAFLTCQAEAYPANLTYTWF 261 Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT 388 +G+ + ++R + + DG + L T ++ + T + S + S LT Sbjct: 262 QGSNNVFL--LNRLQPRVRILVDG-SFLIQRVTPEDAGKYTCIPSNGMWKSPS-ASAYLT 317 Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA-WYFEGEALIQNHRRN-- 445 V P +T+ P+ LPI V C P ++ W +G AL + Sbjct: 318 VLH-----PAYVTSMPAETYLPIGMRGVIKCPVRANPPLLLVNWTKDGHALELDKYPGWY 372 Query: 446 VTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 V DG+LV+ + G YTC + +G Sbjct: 373 VDEDGSLVIATGNDDALGIYTCTPYNSYG 401 Score = 77.0 bits (181), Expect = 3e-12 Identities = 84/321 (26%), Positives = 122/321 (38%), Gaps = 16/321 (4%) Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77 P V V TL C A G+P P + W + GV + S + G L + G Sbjct: 143 PTYVEVRVGDTLTLTCVAYGNPQPVVTWKRDGVTLESG-DKVQASNGSLSIVGVERG--- 198 Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137 +AGVY C A + G + L + PE+ L C Sbjct: 199 -NAGVYTCHAFSDEGEVTHTSRVLVQG--PPIIVVPPENTTVNVSQDAFLTCQAEAYPAN 255 Query: 138 PNVYW--KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195 W N LL R+ ++ G+ +IQ DAG+Y CI N SA A Sbjct: 256 LTYTWFQGSNNVFLLNRLQPRVRILVDGSFLIQRVTPEDAGKYTCIPSNGMWKSPSASAY 315 Query: 196 LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK---VL 252 L + Y+ + P + G +C V +P P +L + G + L + V Sbjct: 316 LTVLHPAYVTSMPAETYLPIGMRGVIKCPVRANP-PLLLVNWTKDGHALELDKYPGWYVD 374 Query: 253 DDGSLRLDNVILADEGEYSCEAENS--VGAVSASGYLTVYDPPS-INLSPNSVNVESGNV 309 +DGSL + G Y+C NS G VS + + +PPS I++ + G Sbjct: 375 EDGSLVIATGNDDALGIYTCTPYNSYGTGGVSLPTEVILKEPPSFIDVPSEEYFQDVGRE 434 Query: 310 ARFTCTATGRPEPTMFWSVEG 330 C+A G P P + WS G Sbjct: 435 LVIPCSAVGDPPPLIRWSKLG 455 Score = 73.7 bits (173), Expect = 3e-11 Identities = 81/310 (26%), Positives = 128/310 (41%), Gaps = 21/310 (6%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSP-AIRWYKGG--VLVVS--DTHRSILPAGGL 66 P I+ P + TV Q A L C+A P+ W++G V +++ IL G Sbjct: 226 PIIVVPPENTTVNVSQDAFLTCQAEAYPANLTYTWFQGSNNVFLLNRLQPRVRILVDGSF 285 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTV 125 R T DAG Y C +N G +S +A+ ++ VL + P G Sbjct: 286 LIQRVTP----EDAGKYTCIPSN--GMWKSPSASAYLTVLHPAYVTSMPAETYLPIGMRG 339 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 V++C P V W K+G L D ++ + G+LVI G Y C N+ Sbjct: 340 VIKCPVRANPPLLLVNWTKDGHALELDKYPGWYVDEDGSLVIATGNDDALGIYTCTPYNS 399 Query: 186 AGTRESAIATLKIHIKP--YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 GT ++ T I +P ++ E+ G + C GDP P + W + G Sbjct: 400 YGTGGVSLPTEVILKEPPSFIDVPSEEYFQDVGRELVIPCSAVGDPPPLIRWSKLGLPGK 459 Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSA--SGYLTVYDPPSI-NLSPN 300 ++ + SL + + G + C A N V +SA + Y+ P ++ N+S Sbjct: 460 ---SAAQMDANSSLVFRPLTKEEHGIWECSATNHVATISARTAIYVLGTSPHAVTNISAL 516 Query: 301 SVNVESGNVA 310 S+ V S NV+ Sbjct: 517 SL-VSSVNVS 525 Score = 68.1 bits (159), Expect = 1e-09 Identities = 62/239 (25%), Positives = 104/239 (43%), Gaps = 29/239 (12%) Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEA---ENSVGAVSASG----YLTVYDPPSINLS 298 LGR ++ + SL ++++ D+G Y C + G +LTV PPS + Sbjct: 82 LGRTRIEEGASLHIESLRSEDQGWYECRVLFLDRHHGEEDFQNGTWVHLTVNSPPSFRET 141 Query: 299 PNS-VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 P + V V G+ TC A G P+P + W +G S DK A+ +G L+ Sbjct: 142 PPTYVEVRVGDTLTLTCVAYGNPQPVVTWKRDGVTL-----ESGDKVQAS---NG--SLS 191 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417 I ++ ++ C A + G ++ V + PPII P N T+ + A Sbjct: 192 IVGVERGNA-GVYTCHAFSDEGEVTHTSRVLV-----QGPPIIVVPPENTTVNVSQDAFL 245 Query: 418 PCTAICTPEPIIAWYFEG--EALIQNH---RRNVTNDGTLVLKDLDKSDSGTYTCVASS 471 C A P + +F+G + N R + DG+ +++ + D+G YTC+ S+ Sbjct: 246 TCQAEAYPANLTYTWFQGSNNVFLLNRLQPRVRILVDGSFLIQRVTPEDAGKYTCIPSN 304 >UniRef50_Q6UXZ4 Cluster: Netrin receptor UNC5D precursor; n=44; Euteleostomi|Rep: Netrin receptor UNC5D precursor - Homo sapiens (Human) Length = 953 Score = 103 bits (246), Expect = 4e-20 Identities = 63/203 (31%), Positives = 101/203 (49%), Gaps = 13/203 (6%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRS---ILPAGG 65 G P+ IE+P D + + P L C+A P+ I + G V + H S + + G Sbjct: 51 GTLPHFIEEPDDAYIIKSNPIALRCKA--RPAMQIFFKCNGEWVHQNEHVSEETLDESSG 108 Query: 66 L----FFLRATHGRVHSDAGV--YWCE--ATNSYGTARSRNATLHVAVLREEFRLEPESK 117 L F+ T +V G YWC+ A + GT++SR A++ +A LR+ F +P+ + Sbjct: 109 LKVREVFINVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGR 168 Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR 177 + +VL C PP G P V W KN + + + D + NL+I+ AR +D+G Sbjct: 169 EVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGN 228 Query: 178 YQCIARNAAGTRESAIATLKIHI 200 Y C+A N R S AT+ +++ Sbjct: 229 YTCMAANIVAKRRSLSATVVVYV 251 Score = 35.9 bits (79), Expect = 6.7 Identities = 20/71 (28%), Positives = 32/71 (45%), Gaps = 3/71 (4%) Query: 404 PSNQTLPIKSMAVFPCTAI-CTPEPIIAWYFEGEALIQNHRRNVTN--DGTLVLKDLDKS 460 P + +PI+ M V C P + W E + N+ D L+++ S Sbjct: 165 PQGREVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLS 224 Query: 461 DSGTYTCVASS 471 DSG YTC+A++ Sbjct: 225 DSGNYTCMAAN 235 >UniRef50_Q6PDN3 Cluster: Myosin light chain kinase, smooth muscle; n=34; Euteleostomi|Rep: Myosin light chain kinase, smooth muscle - Mus musculus (Mouse) Length = 1941 Score = 103 bits (246), Expect = 4e-20 Identities = 100/353 (28%), Positives = 133/353 (37%), Gaps = 42/353 (11%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-DTHRSILPAGGLFFLR 70 P QP V Q C G P P + W+ G+ V + + G L Sbjct: 402 PRFESQPQSQEVTEGQTVKFICEVSGIPKPDVGWFLEGIPVRRREGITEVYEDGVSHHLC 461 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATL----HVAVLREEFRLEPESKQSAQGDTVV 126 R D+ Y C A+NS G + L ++A F + +G V Sbjct: 462 LLRARTR-DSRKYSCTASNSLGQVSCSWSLLVDRPNLAQTAPSFSSVLKDSVVIEGQDFV 520 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARN 184 L C +G+P P V W NGQ + F + + G L IQDA D G Y C+A N Sbjct: 521 LRC-SVQGTPAPRVTWLLNGQPIQFAHS----ICEAGVAELHIQDALPEDRGTYTCLAEN 575 Query: 185 AAGTRESAIATLKIH-------------------IKPYLITGPEDVVAQTGSSVTFQCRV 225 A G + S AT+ + I P + G D+ GS VT +V Sbjct: 576 AMG-QVSCSATVTVQEKKGEGEREHRLSPARSKPIAPIFLQGLSDLKVMDGSQVTMTVQV 634 Query: 226 GGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVS 282 G+P P+V+W G G SL + V D G Y+CEA NS G V Sbjct: 635 SGNPPPEVIWLHD-GNEIQESEDFHFEQKGGWHSLCIQEVFPEDTGTYTCEAWNSAGEVR 693 Query: 283 ASGYLTVYDP-----PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330 LTV +P P P SV G +C G P PT+ W +G Sbjct: 694 TRAVLTVQEPHDGTQPWFISKPRSVTATLGQSVLISCAIAGDPFPTVHWLRDG 746 Score = 96.7 bits (230), Expect = 3e-18 Identities = 104/400 (26%), Positives = 164/400 (41%), Gaps = 47/400 (11%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLF-DGDSRMHLVDG--GNLV 166 F +P+S++ +G TV C G P+P+V W G + +G + ++ DG +L Sbjct: 404 FESQPQSQEVTEGQTVKFIC-EVSGIPKPDVGWFLEGIPVRRREGITEVY-EDGVSHHLC 461 Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP------EDVVAQTGSSVT 220 + AR D+ +Y C A N+ G + S +L + T P +D V G Sbjct: 462 LLRARTRDSRKYSCTASNSLG-QVSCSWSLLVDRPNLAQTAPSFSSVLKDSVVIEGQDFV 520 Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSV 278 +C V G P P V W + G + + + G L + + + D G Y+C AEN++ Sbjct: 521 LRCSVQGTPAPRVTWLLN--GQPIQFAH-SICEAGVAELHIQDALPEDRGTYTCLAENAM 577 Query: 279 GAVSASGYLTVYDPPSIN-----LSP--------------NSVNVESGNVARFTCTATGR 319 G VS S +TV + LSP + + V G+ T +G Sbjct: 578 GQVSCSATVTVQEKKGEGEREHRLSPARSKPIAPIFLQGLSDLKVMDGSQVTMTVQVSGN 637 Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379 P P + W +GN + +H G L I + D+ T C A N AG Sbjct: 638 PPPEVIWLHDGNEI-----QESEDFHFEQK-GGWHSLCIQEVFPEDT-GTYTCEAWNSAG 690 Query: 380 SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI 439 R LTV D P + P + T + + C P P + W +G AL Sbjct: 691 EVRTRAVLTVQEPHDGTQPWFISKPRSVTATLGQSVLISCAIAGDPFPTVHWLRDGRALS 750 Query: 440 QN--HRRNVTNDG--TLVLKDLDKSDSGTYTCVASSRHGK 475 ++ H + N+ TLVLK++ +G Y + +R G+ Sbjct: 751 KDSGHFELLQNEDVFTLVLKNVQPWHAGQYEILLKNRVGE 790 Score = 89.4 bits (212), Expect = 5e-16 Identities = 92/300 (30%), Positives = 126/300 (42%), Gaps = 30/300 (10%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 D V Q L C G+P+P + W G + H SI AG + D Sbjct: 510 DSVVIEGQDFVLRCSVQGTPAPRVTWLLNGQ-PIQFAH-SICEAGVAEL--HIQDALPED 565 Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLR----EEFRLEP-ESKQSA----QG--DTVVLE 128 G Y C A N+ G S +AT+ V + E RL P SK A QG D V++ Sbjct: 566 RGTYTCLAENAMGQV-SCSATVTVQEKKGEGEREHRLSPARSKPIAPIFLQGLSDLKVMD 624 Query: 129 ------CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCI 181 + G+P P V W +G + D G + L IQ+ D G Y C Sbjct: 625 GSQVTMTVQVSGNPPPEVIWLHDGNEIQESEDFHFEQKGGWHSLCIQEVFPEDTGTYTCE 684 Query: 182 ARNAAG-TRESAIATLKI-H--IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 A N+AG R A+ T++ H +P+ I+ P V A G SV C + GDP P V W R Sbjct: 685 AWNSAGEVRTRAVLTVQEPHDGTQPWFISKPRSVTATLGQSVLISCAIAGDPFPTVHWLR 744 Query: 238 SAGGGNMPLGRVKVL---DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294 + G ++L D +L L NV G+Y +N VG S L +++ PS Sbjct: 745 DGRALSKDSGHFELLQNEDVFTLVLKNVQPWHAGQYEILLKNRVGECSCQVSLMLHNSPS 804 Score = 70.1 bits (164), Expect = 3e-10 Identities = 82/312 (26%), Positives = 117/312 (37%), Gaps = 36/312 (11%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---SLR 258 P + P+ G +V F C V G P PDV W G +V +DG L Sbjct: 402 PRFESQPQSQEVTEGQTVKFICEVSGIPKPDVGWFLEGIPVRRREGITEVYEDGVSHHLC 461 Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA------RF 312 L D +YSC A NS+G VS S L V P +P+ +V +V Sbjct: 462 LLRARTRDSRKYSCTASNSLGQVSCSWSLLVDRPNLAQTAPSFSSVLKDSVVIEGQDFVL 521 Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372 C+ G P P + W + G + I F H+ GV L I D D R T C Sbjct: 522 RCSVQGTPAPRVTWLLNG-QPIQFA-------HSICE-AGVAELHIQDALPED-RGTYTC 571 Query: 373 SAVNYAGSSFVRGKLTV---TSDDDRP-----------PPIITNGPSNQTLPIKSMAVFP 418 A N G +TV + +R PI G S+ + S Sbjct: 572 LAENAMGQVSCSATVTVQEKKGEGEREHRLSPARSKPIAPIFLQGLSDLKVMDGSQVTMT 631 Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGK 475 P P + W +G + ++ + G +L ++++ D+GTYTC A + G+ Sbjct: 632 VQVSGNPPPEVIWLHDGNEIQESEDFHFEQKGGWHSLCIQEVFPEDTGTYTCEAWNSAGE 691 Query: 476 YVWSGALLVDSP 487 L V P Sbjct: 692 VRTRAVLTVQEP 703 Score = 64.1 bits (149), Expect = 2e-08 Identities = 53/198 (26%), Positives = 83/198 (41%), Gaps = 10/198 (5%) Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70 AP ++ D+ V T+ + G+P P + W G + GG L Sbjct: 610 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHDGNEIQESEDFHFEQKGGWHSL- 668 Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE----FRLEPESKQSAQGDTVV 126 D G Y CEA NS G R+R A L V + F +P S + G +V+ Sbjct: 669 CIQEVFPEDTGTYTCEAWNSAGEVRTR-AVLTVQEPHDGTQPWFISKPRSVTATLGQSVL 727 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGD--SRMHLVDGGNLVIQDARQTDAGRYQCIARN 184 + C G P P V+W ++G+ L D + D LV+++ + AG+Y+ + +N Sbjct: 728 ISC-AIAGDPFPTVHWLRDGRALSKDSGHFELLQNEDVFTLVLKNVQPWHAGQYEILLKN 786 Query: 185 AAGTRESAIATLKIHIKP 202 G S +L +H P Sbjct: 787 RVG-ECSCQVSLMLHNSP 803 Score = 56.4 bits (130), Expect = 4e-06 Identities = 60/223 (26%), Positives = 85/223 (38%), Gaps = 21/223 (9%) Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF-D 351 P P S V G +F C +G P+P + W +EG P R+ T V+ D Sbjct: 402 PRFESQPQSQEVTEGQTVKFICEVSGIPKPDVGWFLEG-----IPVRRREGI--TEVYED 454 Query: 352 GVTV-LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410 GV+ L + DSR C+A N G L V DRP + PS ++ Sbjct: 455 GVSHHLCLLRARTRDSRK-YSCTASNSLGQVSCSWSLLV----DRPN-LAQTAPSFSSVL 508 Query: 411 IKSMA------VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGT 464 S+ V C+ TP P + W G+ + H L ++D D GT Sbjct: 509 KDSVVIEGQDFVLRCSVQGTPAPRVTWLLNGQPIQFAHSICEAGVAELHIQDALPEDRGT 568 Query: 465 YTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPP 507 YTC+A + G+ S + V R + S P P Sbjct: 569 YTCLAENAMGQVSCSATVTVQEKKGEGEREHRLSPARSKPIAP 611 Score = 54.0 bits (124), Expect = 2e-05 Identities = 61/216 (28%), Positives = 87/216 (40%), Gaps = 41/216 (18%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVI 167 F L P + +G T E RG PEP V W + GQ + G + G +LVI Sbjct: 35 FILPPRNLCVKEGATAKFEGRV-RGYPEPQVTWHRKGQAITNGGRFLLDCGVRGTFSLVI 93 Query: 168 QDARQTDAGRYQCIARNAAGTRESAIA------TLKIHIKPYL-------------ITG- 207 R+ D G+Y C A N +G R+ + ++K +P L I G Sbjct: 94 HTVREEDKGKYTCEASNGSGARQVTVELTVEGNSMKKRDQPVLSKASGFPGETRPSIWGE 153 Query: 208 -PEDVVAQTGSSVT-------FQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGS 256 P + G +V F C++ G P P V W + GN+PL RV + + Sbjct: 154 CPPKFATKLGRAVVKEGQMWRFSCKITGRPPPQVTWLK----GNVPLQPSARVSMSEKNG 209 Query: 257 ---LRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 L + V D G Y+C N G S S L++ Sbjct: 210 MQILEIRGVTRDDLGVYTCMVVNGSGKASMSAELSI 245 Score = 52.8 bits (121), Expect = 5e-05 Identities = 31/101 (30%), Positives = 52/101 (51%), Gaps = 3/101 (2%) Query: 192 AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW-RRSAGGGNMPLGRVK 250 A+A K H+KPY D+ GS+ F C++ G P P+V+W + ++ Sbjct: 1821 AVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID 1880 Query: 251 VLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 +DG SL + +V D+ +Y+C+A NS+G + + L V Sbjct: 1881 YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1921 Score = 51.6 bits (118), Expect = 1e-04 Identities = 36/123 (29%), Positives = 56/123 (45%), Gaps = 12/123 (9%) Query: 504 PGPPT-KPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562 P PP P ++ +S+TLSW ++ G S++ Y VE++ E + W Sbjct: 1353 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYNVEIWDTE----------DKVWKE 1402 Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSN 622 +A T + V+ L+P Y F VR N +G S PS S+ VG+ + VS+ Sbjct: 1403 LAT-CRSTSFNVQDLLPDREYKFRVRAVNVYGTSEPSQESELTAVGEKPEEPKDEVEVSD 1461 Query: 623 STE 625 E Sbjct: 1462 DDE 1464 Score = 49.6 bits (113), Expect = 5e-04 Identities = 34/104 (32%), Positives = 52/104 (50%), Gaps = 7/104 (6%) Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250 S ++++ + P I P ++ + G++ F+ RV G P P V W R G + G Sbjct: 22 SKVSSMPLTEAPAFILPPRNLCVKEGATAKFEGRVRGYPEPQVTWHRK--GQAITNGGRF 79 Query: 251 VLDDG-----SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 +LD G SL + V D+G+Y+CEA N GA + LTV Sbjct: 80 LLDCGVRGTFSLVIHTVREEDKGKYTCEASNGSGARQVTVELTV 123 Score = 46.0 bits (104), Expect = 0.006 Identities = 33/113 (29%), Positives = 48/113 (42%), Gaps = 4/113 (3%) Query: 379 GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438 G+ FV G + S + P + P +Q + F C P+P + W+ EG + Sbjct: 383 GNKFVTGNIPRESQRESTFPRFESQPQSQEVTEGQTVKFICEVSGIPKPDVGWFLEGIPV 442 Query: 439 IQNHR-RNVTNDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 + V DG L L DS Y+C AS+ G+ S +LLVD P Sbjct: 443 RRREGITEVYEDGVSHHLCLLRARTRDSRKYSCTASNSLGQVSCSWSLLVDRP 495 Score = 42.7 bits (96), Expect = 0.059 Identities = 33/116 (28%), Positives = 44/116 (37%), Gaps = 3/116 (2%) Query: 9 GEAPYIIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67 GE P L V + Q +C+ G P P + W KG V + S+ G+ Sbjct: 152 GECPPKFATKLGRAVVKEGQMWRFSCKITGRPPPQVTWLKGNVPLQPSARVSMSEKNGMQ 211 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123 L G D GVY C N G A S +A L + L RL ++ D Sbjct: 212 ILE-IRGVTRDDLGVYTCMVVNGSGKA-SMSAELSIPGLDNASRLAVRGTKAPSPD 265 Score = 42.3 bits (95), Expect = 0.078 Identities = 31/98 (31%), Positives = 44/98 (44%), Gaps = 7/98 (7%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG--GLF 67 EAP I P ++ V A R G P P + W++ G +++ R +L G G F Sbjct: 31 EAPAFILPPRNLCVKEGATAKFEGRVRGYPEPQVTWHRKG-QAITNGGRFLLDCGVRGTF 89 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV 105 L H D G Y CEA+N G +R T+ + V Sbjct: 90 SL-VIHTVREEDKGKYTCEASNGSG---ARQVTVELTV 123 Score = 41.1 bits (92), Expect = 0.18 Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 6/87 (6%) Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL-DDGS---LRLDNVIL 264 +DV G + QC+V DP V W S G + + VL +GS + ++ + Sbjct: 1127 QDVHVAEGEKLLLQCQVISDPPATVTW--SLNGKTLKTTKFIVLAQEGSRFSVSIEKALP 1184 Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYD 291 D G Y C A+NS G S +TV D Sbjct: 1185 EDRGLYKCVAKNSAGQAECSCQVTVDD 1211 Score = 39.9 bits (89), Expect = 0.41 Identities = 33/112 (29%), Positives = 45/112 (40%), Gaps = 3/112 (2%) Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66 + G AP E+ DV VA + L C+ P + W G + T +L G Sbjct: 1115 SQGSAPVFKEKLQDVHVAEGEKLLLQCQVISDPPATVTWSLNG-KTLKTTKFIVLAQEGS 1173 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESK 117 F + + D G+Y C A NS G A S T+ A E + PE K Sbjct: 1174 RFSVSIEKALPEDRGLYKCVAKNSAGQAECSCQVTVDDAQTSENTK-APEMK 1224 Score = 37.9 bits (84), Expect = 1.7 Identities = 18/62 (29%), Positives = 28/62 (45%), Gaps = 1/62 (1%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT-HRSILPAGGLF 67 G P+ I +P VT Q ++C G P P + W + G + D+ H +L +F Sbjct: 706 GTQPWFISKPRSVTATLGQSVLISCAIAGDPFPTVHWLRDGRALSKDSGHFELLQNEDVF 765 Query: 68 FL 69 L Sbjct: 766 TL 767 Score = 37.5 bits (83), Expect = 2.2 Identities = 26/103 (25%), Positives = 47/103 (45%), Gaps = 7/103 (6%) Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 PP V+ G + RF+C TGRP P + W ++GN P + + + + Sbjct: 155 PPKFATKLGRAVVKEGQMWRFSCKITGRPPPQVTW-LKGN----VP-LQPSARVSMSEKN 208 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394 G+ +L I ++D C VN +G + + +L++ D+ Sbjct: 209 GMQILEIRGVTRDD-LGVYTCMVVNGSGKASMSAELSIPGLDN 250 Score = 37.5 bits (83), Expect = 2.2 Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 6/84 (7%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LV 166 F+ + + A+G+ ++L+C P V W NG+TL + L G+ + Sbjct: 1122 FKEKLQDVHVAEGEKLLLQC-QVISDPPATVTWSLNGKTL--KTTKFIVLAQEGSRFSVS 1178 Query: 167 IQDARQTDAGRYQCIARNAAGTRE 190 I+ A D G Y+C+A+N+AG E Sbjct: 1179 IEKALPEDRGLYKCVAKNSAGQAE 1202 >UniRef50_Q9UPX0 Cluster: Protein turtle homolog B precursor; n=21; Euteleostomi|Rep: Protein turtle homolog B precursor - Homo sapiens (Human) Length = 1349 Score = 102 bits (245), Expect = 5e-20 Identities = 87/301 (28%), Positives = 128/301 (42%), Gaps = 17/301 (5%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSP-AIRWY--KGGVLVVSDTHRS--ILPAGGL 66 P+I+ P ++TV Q A L CRA P WY V +D IL G L Sbjct: 229 PFIVSPPENITVNISQDALLTCRAEAYPGNLTYTWYWQDENVYFQNDLKLRVRILIDGTL 288 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126 R D+G Y C +NS G + S +A L V + P G Sbjct: 289 IIFRVKP----EDSGKYTCVPSNSLGRSPSASAYLTVQYPARVLNMPPVIYVPV-GIHGY 343 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186 + C P V W K+G+ L + + L++ G++ I++A + G Y C+ N Sbjct: 344 IRCPVDAEPPATVVKWNKDGRPLQVEKNLGWTLMEDGSIRIEEATEEALGTYTCVPYNTL 403 Query: 187 GTR-ESAIATLKIHIKPYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244 GT +SA A L + PY P + + G + C GDP P + WR+ G Sbjct: 404 GTMGQSAPARLVLKDPPYFTVLPGWEYRQEAGRELLIPCAAAGDPFPVITWRKV---GKP 460 Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304 + L GSL+ + D GE+ C A N V +++AS +LTV + +P SV V Sbjct: 461 SRSKHSALPSGSLQFRALSKEDHGEWECVATNVVTSITASTHLTVIG--TSPHAPGSVRV 518 Query: 305 E 305 + Sbjct: 519 Q 519 Score = 99.5 bits (237), Expect = 5e-19 Identities = 97/366 (26%), Positives = 151/366 (41%), Gaps = 27/366 (7%) Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT 173 P+ ++ +G ++ + C G+P+P V W K G TLL G S + V G+L + + Sbjct: 146 PQYIEAKEGGSITMTCTA-FGNPKPIVTWLKEG-TLL--GASGKYQVSDGSLTVTSVSRE 201 Query: 174 DAGRYQCIARNAAGTRESAIAT-LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--- 229 D G Y C A + G E+ T L + P++++ PE++ CR P Sbjct: 202 DRGAYTCRAYSIQG--EAVHTTHLLVQGPPFIVSPPENITVNISQDALLTCRAEAYPGNL 259 Query: 230 LPDVLWR-RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG-AVSASGYL 287 W+ + N RV++L DG+L + V D G+Y+C NS+G + SAS YL Sbjct: 260 TYTWYWQDENVYFQNDLKLRVRILIDGTLIIFRVKPEDSGKYTCVPSNSLGRSPSASAYL 319 Query: 288 TVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF-WSVEGNRTIIFPGMSRDKYHA 346 TV P + P + V G C P T+ W+ +G P Sbjct: 320 TVQYPARVLNMPPVIYVPVGIHGYIRCPVDAEPPATVVKWNKDGR-----PLQVEKNLGW 374 Query: 347 TAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPS- 405 T + DG + I + + ++ T C N G+ + D PP T P Sbjct: 375 TLMEDGS--IRIEEATE-EALGTYTCVPYNTLGTMGQSAPARLVLKD---PPYFTVLPGW 428 Query: 406 NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465 + PC A P P+I W G+ H + G+L + L K D G + Sbjct: 429 EYRQEAGRELLIPCAAAGDPFPVITWRKVGKPSRSKH--SALPSGSLQFRALSKEDHGEW 486 Query: 466 TCVASS 471 CVA++ Sbjct: 487 ECVATN 492 Score = 95.5 bits (227), Expect = 8e-18 Identities = 82/336 (24%), Positives = 132/336 (39%), Gaps = 19/336 (5%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPA-TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63 ++T P E P A+ + T+ C A G+P P + W K G L+ + + Sbjct: 132 HLTINAPPTFTETPPQYIEAKEGGSITMTCTAFGNPKPIVTWLKEGTLLGASGKYQVSD- 190 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-G 122 G L + D G Y C A + G A T H+ V F + P + Sbjct: 191 GSLTVTSVSR----EDRGAYTCRAYSIQGEAVH---TTHLLVQGPPFIVSPPENITVNIS 243 Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS--RMHLVDGGNLVIQDARQTDAGRYQC 180 +L C W + + F D R+ ++ G L+I + D+G+Y C Sbjct: 244 QDALLTCRAEAYPGNLTYTWYWQDENVYFQNDLKLRVRILIDGTLIIFRVKPEDSGKYTC 303 Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL-WRRSA 239 + N+ G SA A L + ++ P + G +C V +P V+ W + Sbjct: 304 VPSNSLGRSPSASAYLTVQYPARVLNMPPVIYVPVGIHGYIRCPVDAEPPATVVKWNKDG 363 Query: 240 GGGNMP--LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV--SASGYLTVYDPPSI 295 + LG +++DGS+R++ G Y+C N++G + SA L + DPP Sbjct: 364 RPLQVEKNLGWT-LMEDGSIRIEEATEEALGTYTCVPYNTLGTMGQSAPARLVLKDPPYF 422 Query: 296 NLSPN-SVNVESGNVARFTCTATGRPEPTMFWSVEG 330 + P E+G C A G P P + W G Sbjct: 423 TVLPGWEYRQEAGRELLIPCAAAGDPFPVITWRKVG 458 Score = 87.4 bits (207), Expect = 2e-15 Identities = 77/248 (31%), Positives = 111/248 (44%), Gaps = 27/248 (10%) Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEA-----ENSVGAVSASGYLTVYDPPSINLSPNS 301 GR + D SLRL+ V D+G Y C+ + + +LT+ PP+ +P Sbjct: 88 GRASLHDKASLRLEQVRSEDQGWYECKVLMLDQQYDTFHNGSWVHLTINAPPTFTETPPQ 147 Query: 302 -VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360 + + G TCTA G P+P + W EG T++ G S KY V DG LT+ Sbjct: 148 YIEAKEGGSITMTCTAFGNPKPIVTWLKEG--TLL--GAS-GKYQ---VSDGS--LTVTS 197 Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420 + D R C A + G + L V PP I + P N T+ I A+ C Sbjct: 198 VSRED-RGAYTCRAYSIQGEAVHTTHLLVQG-----PPFIVSPPENITVNISQDALLTCR 251 Query: 421 AICTPEPII-AWYFEGEAL-IQNH---RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 A P + WY++ E + QN R + DGTL++ + DSG YTCV S+ G+ Sbjct: 252 AEAYPGNLTYTWYWQDENVYFQNDLKLRVRILIDGTLIIFRVKPEDSGKYTCVPSNSLGR 311 Query: 476 YVWSGALL 483 + A L Sbjct: 312 SPSASAYL 319 Score = 85.4 bits (202), Expect = 8e-15 Identities = 98/383 (25%), Positives = 155/383 (40%), Gaps = 36/383 (9%) Query: 111 RLEPESKQSAQGDTVVLEC---LPPRGSPEPNVY-WKKNGQTL-LF------------DG 153 R EPE + G++VVL C P G P P V W K G + +F + Sbjct: 27 REEPEFVTARAGESVVLRCDVIHPVTGQPPPYVVEWFKFGVPIPIFIKFGYYPPHVDPEY 86 Query: 154 DSRMHLVDGGNLVIQDARQTDAGRYQC----IARNAAGTRESAIATLKIHIKP-YLITGP 208 R L D +L ++ R D G Y+C + + + L I+ P + T P Sbjct: 87 AGRASLHDKASLRLEQVRSEDQGWYECKVLMLDQQYDTFHNGSWVHLTINAPPTFTETPP 146 Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268 + + A+ G S+T C G+P P V W + G G+ +V DGSL + +V D G Sbjct: 147 QYIEAKEGGSITMTCTAFGNPKPIVTWLKE-GTLLGASGKYQV-SDGSLTVTSVSREDRG 204 Query: 269 EYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328 Y+C A + G + +L V PP I P ++ V A TC A P + Sbjct: 205 AYTCRAYSIQGEAVHTTHLLVQGPPFIVSPPENITVNISQDALLTCRAEAYPGNLTYTWY 264 Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT 388 + + F + K + DG T++ ++ + T V S + S LT Sbjct: 265 WQDENVYF--QNDLKLRVRILIDG-TLIIFRVKPEDSGKYTCVPSN-SLGRSPSASAYLT 320 Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC-TPEPIIAWYFEGEAL--IQNHRRN 445 V + P + N P +P+ C P ++ W +G L +N Sbjct: 321 V-----QYPARVLNMPPVIYVPVGIHGYIRCPVDAEPPATVVKWNKDGRPLQVEKNLGWT 375 Query: 446 VTNDGTLVLKDLDKSDSGTYTCV 468 + DG++ +++ + GTYTCV Sbjct: 376 LMEDGSIRIEEATEEALGTYTCV 398 Score = 53.6 bits (123), Expect = 3e-05 Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 2/92 (2%) Query: 397 PPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLK 455 PP T P + ++ CTA P+PI+ W EG L + + V+ DG+L + Sbjct: 138 PPTFTETPPQYIEAKEGGSITMTCTAFGNPKPIVTWLKEGTLLGASGKYQVS-DGSLTVT 196 Query: 456 DLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 + + D G YTC A S G+ V + LLV P Sbjct: 197 SVSREDRGAYTCRAYSIQGEAVHTTHLLVQGP 228 Score = 42.3 bits (95), Expect = 0.078 Identities = 61/260 (23%), Positives = 112/260 (43%), Gaps = 22/260 (8%) Query: 39 PSPAIRWYKGG--VLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGT-AR 95 P+ ++W K G + V + +++ G + AT + G Y C N+ GT + Sbjct: 353 PATVVKWNKDGRPLQVEKNLGWTLMEDGSIRIEEATEEAL----GTYTCVPYNTLGTMGQ 408 Query: 96 SRNATLHVAVLREE--FRLEP--ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLF 151 S A L VL++ F + P E +Q A G +++ C G P P + W+K G+ Sbjct: 409 SAPARL---VLKDPPYFTVLPGWEYRQEA-GRELLIPCAAA-GDPFPVITWRKVGKP--- 460 Query: 152 DGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDV 211 S+ + G+L + + D G ++C+A N + ++ I P+ Sbjct: 461 -SRSKHSALPSGSLQFRALSKEDHGEWECVATNVVTSITASTHLTVIGTSPHAPGSVRVQ 519 Query: 212 VAQTGSSVTFQCRV-GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGE 269 V+ T ++V+++ GG +W + A G + V S L +D + + Sbjct: 520 VSMTTANVSWEPGYDGGYEQTFSVWMKRAQFGPHDWLSLPVPPGPSWLLVDTLEPETAYQ 579 Query: 270 YSCEAENSVGAVSASGYLTV 289 +S A+N +G + S +TV Sbjct: 580 FSVLAQNKLGTSAFSEVVTV 599 >UniRef50_UPI0000E48847 Cluster: PREDICTED: similar to titin isoform N2-A; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to titin isoform N2-A - Strongylocentrotus purpuratus Length = 10984 Score = 102 bits (244), Expect = 7e-20 Identities = 144/591 (24%), Positives = 226/591 (38%), Gaps = 55/591 (9%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFFLRATHGRVHSD 79 V +PA C + I W K + D + + +G L+ V SD Sbjct: 1360 VQAVEDEPAVFTCEISDDNAEVI-WLKNEEEIKPDDEKYEFVVSGKKRGLKIKSTDV-SD 1417 Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139 + C+ + +A S T H+ + + + K + VV EC + Sbjct: 1418 TAEFTCKTKDKTSSA-SLTVTEHIPTISHTLK---DVKIEEGSNEVVFEC--ETDVETAD 1471 Query: 140 VYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197 V W G+ ++ D + G +L+++D DAG + C G E+ IA L Sbjct: 1472 VAWLHKGKDIVEDNSKFVIKRKGRRHSLIVKDVSVEDAGEFTC----RIGVHET-IAELI 1526 Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS- 256 + ++ +L P++ A G +TF+ + D DV W + G P VK++ DG Sbjct: 1527 VEVE-FLAPLPKEQSAIPGDEITFEVELTKDT-EDVFWLKD-GQKIKPGDNVKIVKDGKK 1583 Query: 257 --LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN--SVNVESGNVARF 312 L + V D+ YS A G L V PP IN+ P +++V++G Sbjct: 1584 HKLIIKKVDFDDDAVYSFNA----GDQKCDCNLNVSAPPKINVDPKLTNISVKAGTKIAI 1639 Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372 T TG P WS +G+ I R K A LTI+ T+++D T Sbjct: 1640 EATVTGSPAAVTTWS-KGDTPI--ESTKRFKIEAGKGPKASIRLTIDKTERSDL-GTYTL 1695 Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432 +A N G+ + V D +PP T+ +T P V+ P+I + Sbjct: 1696 TAANDLGTDTAIIFIIVL-DKPQPP---TSLSITETTPESVTLVWTAPEDDGGSPVIEYV 1751 Query: 433 FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492 E + +N V L + + K G S + S P+ Sbjct: 1752 IEKRDMKRNTWTKVDTTSELTCR-VPKLVEGNEYLFRVSATNELGTSEPFTTSEPVTAKY 1810 Query: 493 HFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNN 552 F +P P+KP T +V T +TL+W+ + G S + GY +E Sbjct: 1811 QF-------DVPHAPSKPETSDVIQTEMTLTWTPPDFNGGSEVTGYIIE----------R 1853 Query: 553 TPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602 + WV I + V + + VK LI G +Y F V N G S PS S Sbjct: 1854 KEADKTRWVKITKETVTELTFRVKDLIEGTSYEFRVYAINKAGTSKPSEPS 1904 Score = 91.1 bits (216), Expect = 2e-16 Identities = 197/828 (23%), Positives = 309/828 (37%), Gaps = 115/828 (13%) Query: 15 IEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73 I +PL D T A L C +P ++W K G ++ + ++ + G Sbjct: 1264 ITKPLEDTTTAFETTVVLECEVDNEKAP-VKWMKNGK-EITKMPKYLMESKGKKRRLTIF 1321 Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133 + D G Y C + S A L V EF E +S Q+ + + V C Sbjct: 1322 ETIPEDEGDYTCVVGDE-----STVAVLAVEPAPIEFLSEIQSVQAVEDEPAVFTCEISD 1376 Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRES 191 + E V W KN + + D + +V G L I+ +D + C ++ S Sbjct: 1377 DNAE--VIWLKNEEEIKPDDEKYEFVVSGKKRGLKIKSTDVSDTAEFTCKTKDKTS---S 1431 Query: 192 AIATLKIHIKPYLITGPEDVVAQTGSS-VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250 A T+ HI P + +DV + GS+ V F+C + DV W + Sbjct: 1432 ASLTVTEHI-PTISHTLKDVKIEEGSNEVVFECETDVETA-DVAWLHKGKDIVEDNSKFV 1489 Query: 251 VLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESG 307 + G SL + +V + D GE++C +G L V + + P + G Sbjct: 1490 IKRKGRRHSLIVKDVSVEDAGEFTCR----IGVHETIAELIV-EVEFLAPLPKEQSAIPG 1544 Query: 308 NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT-VLTINDTDKNDS 366 + F T E +FW +G + I PG + V DG L I D +D Sbjct: 1545 DEITFEVELTKDTED-VFWLKDGQK--IKPGDN-----VKIVKDGKKHKLIIKKVDFDDD 1596 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426 + N AG L V++ PP I P + +K+ A T Sbjct: 1597 ----AVYSFN-AGDQKCDCNLNVSA-----PPKINVDPKLTNISVKAGTKIAIEATVTGS 1646 Query: 427 PI-IAWYFEGEALIQNHRRNVTNDGT-------LVLKDLDKSDSGTYTCVASSRHGKYVW 478 P + + +G+ I++ +R G L + ++SD GTYT A++ Sbjct: 1647 PAAVTTWSKGDTPIESTKRFKIEAGKGPKASIRLTIDKTERSDLGTYTLTAAN------- 1699 Query: 479 SGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGY 538 D + I F D P PPT T SVTL W+ G S ++ Y Sbjct: 1700 ------DLGTDTAIIFIIVLDK---PQPPTSLSITETTPESVTLVWTAPEDDGGSPVIEY 1750 Query: 539 QVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598 +E + RN+ W + T V K L+ G Y+F V N G S P Sbjct: 1751 VIEK--------RDMKRNT--WTKVDTTSELTCRVPK-LVEGNEYLFRVSATNELGTSEP 1799 Query: 599 SPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNF 658 S+ VT +Y+ ++ H E + + + L W +F Sbjct: 1800 FTTSEPVTA-----------------KYQFDV--PHAPSKPETSDVIQTEMTLTWTPPDF 1840 Query: 659 Y---YLEGLFIYFRPLDNIT-IEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKF 714 + G I + D ++ +T+ F + L + T YEF + K Sbjct: 1841 NGGSEVTGYIIERKEADKTRWVKITKETVTELT----FRVKDLIEGTSYEFRVYAINKAG 1896 Query: 715 EGKPSNSRV---AQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVV 771 KPS A+ DVP GPP +N TT+ + W+PPE +TGY V+ Sbjct: 1897 TSKPSEPSTPTKAKAPYDVP-GPPAQPTCENVNKTTITVSWTPPE-DDGGSPVTGY--VI 1952 Query: 772 NWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819 DV + + V + T +++LT G Y +I+AE G+G Sbjct: 1953 ERCDVSRGRWVKCNRDKVTELT-FTVSDLTDGGQYQFRISAENAAGVG 1999 Score = 82.6 bits (195), Expect = 6e-14 Identities = 89/325 (27%), Positives = 141/325 (43%), Gaps = 36/325 (11%) Query: 502 SLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV 561 S P P +P NVT S TL+WS G SSI GY +E ++ S PR +R Sbjct: 6571 SQPAAPNEPQISNVTADSATLTWSPPRDDGGSSITGYFIE--KKDKFS----PRWTR--- 6621 Query: 562 VIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVS 621 V V T + V +L+PG Y F V +N G S PS ++S V N G Sbjct: 6622 VNHDAVTDTKFTVPALVPGEEYQFRVVAQNKAGASKPSEPTESTLVRSPFNE----PGAP 6677 Query: 622 NSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMK 681 + E N +T+ + L P + + YY+E D +++ + Sbjct: 6678 GAPETSN--VTETTLTLTWTPPFSDGGSR-----ITGYYVE-------KKDRMSLRWSPV 6723 Query: 682 TILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRV---AQTLDDVPDGPPINI 738 + D ++T L + T+YEF ++ KPS A++ D+P P Sbjct: 6724 NFESTEDTK-LKVTGLTEGTEYEFRVVAENDAGRSKPSAPSYPVKAKSPFDLPSAPG-TP 6781 Query: 739 EMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMT 798 + +++T + L+W+PPE IIT +V + + + V I+ T+ +T Sbjct: 6782 SISDISSTNMTLRWAPPESDGGTVIIT---FIVERREQFSTR-WVQISRFDFTETTFSVT 6837 Query: 799 NLTSGVSYSVQIAAETIIGLGPFSQ 823 L G Y ++AA+ IG+G FS+ Sbjct: 6838 GLKDGNDYEFRVAAKNKIGIGKFSE 6862 Score = 82.6 bits (195), Expect = 6e-14 Identities = 115/440 (26%), Positives = 177/440 (40%), Gaps = 52/440 (11%) Query: 178 YQCIARNAAG----TRESAIATLKIHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPD 232 ++ A N AG ++ SA K I+ P +DV A+ G VT +CR+ +P + Sbjct: 9035 FRVAAENEAGLGAFSKTSAPIVSKTPIELAEFVEPLKDVSAKAGKIVTLECRIS-NPNAE 9093 Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLR---LDNVILADEGEYSCEAENSVGAVSASGYLTV 289 V W + G RV + +G R L NV D G+YSCE G S S +L+V Sbjct: 9094 VKWMKD-GFQIFGYDRVNEIKEGQRRAITLRNVGDRDTGKYSCEC----GKQSTSCWLSV 9148 Query: 290 YDPPSINLSP--NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347 PP+I++ + V V++GN R TG P P + W R +S D Sbjct: 9149 TAPPTIDVKAYKDVVVVKTGNTLRLLVPYTGCPSPKVEWHRHDAR------ISEDTRTHI 9202 Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407 D T +TI + + D+ + + N AG ++ V D P GP Sbjct: 9203 ETRDNRTQITIRNVVRGDTGKFSI-TLTNEAGQETAIIRVNVI---DVP------GPPTG 9252 Query: 408 TLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGT-YT 466 L I + C ++ P +G + IQ++ + + S +T Sbjct: 9253 PLEITDVGRH-CVSLSWEPP----KDDGGSPIQSYTVEQREANRRMWTSVSNYVSHVPFT 9307 Query: 467 CVASSRHGKYVWSGALLVDSPINPNIHFFRAADV---SSLPGPPTKPITHNVTDTSVTLS 523 S +Y + + + P +H + S+P PP KP NV +TL+ Sbjct: 9308 VSGLSEKVEYEFRVCAENINGVGPPLHGIEPVVIVAPYSVPTPPGKPEISNVQRDRMTLT 9367 Query: 524 WSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGIT 582 WS+ + G I GY +E RE S+ W + R + T + +K L G Sbjct: 9368 WSEPSHDGGKPIQGYIIE--RRENF--------SKQWNRVNRDLIKDTTFTIKGLTEGSN 9417 Query: 583 YMFIVRTENSHGLSGPSPVS 602 Y F + N G+ PS VS Sbjct: 9418 YEFRISAVNDTGIGNPSEVS 9437 Score = 79.8 bits (188), Expect = 4e-13 Identities = 120/500 (24%), Positives = 196/500 (39%), Gaps = 56/500 (11%) Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGT 188 +P + +P P V W +NG T+ + + G L + A +TD+G Y A N AG Sbjct: 8491 IPYKATPTPTVSWTQNGDTVQKSNRITIDSNNYGTTLTARTAERTDSGDYVIRASNKAG- 8549 Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV----GGDPLPD-VLWRRSAGGGN 243 ++ T+ + P GP +V + VT GG P+ VL +R G G+ Sbjct: 8550 EDTVTVTVNVVDSPSPPQGPLALVKLGSNEVTLSWSRPRDDGGSPITGYVLEKREGGYGS 8609 Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA--------VSASGYLTVYDPPSI 295 K+ D + R+ + E ++ AEN++G + G V D P Sbjct: 8610 WTNVSSKI-PDTTFRVTKLTEDREYQFRVRAENNLGVSEPLESERIIPKGDYDVPDQPG- 8667 Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355 + +++ +S ++ G T + + R G +R Y + + V Sbjct: 8668 KIKVDTIQSDSVSLTWSRPQRDGGAPVTGYIVEKRERGQPEAGWNRTSYKPV-MDTTIRV 8726 Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT--VTSDDDRPPPIITNGPSNQTLPIKS 413 +++ + + R SAVN AG S + P I + +++ Sbjct: 8727 PRLSEGKEYEFR----VSAVNKAGMSTPAATAAPVIVERPSYAPKIDLGSQFRDVITVRA 8782 Query: 414 MAVFPCTAIC--TPEPIIAWYFEGEALIQNHRR----NVTNDGTLVLKDLDKSDSGTYTC 467 +F TP P +AW + E + + RR T L KD ++DSGTYT Sbjct: 8783 GTLFHLDVPISGTPTPTVAWLMD-EKQVDDGRRIKASTTTYSAVLTNKDARRTDSGTYTI 8841 Query: 468 VASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527 S++ G + + V D S P P K +T ++T SVTL+W Sbjct: 8842 KISNKAGTDTATIRVAV-------------LDKPSAPEGPIK-VT-SITCDSVTLAWEPP 8886 Query: 528 NKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIV 587 G + I GY +E RE P R W + + Y V L G +Y+F V Sbjct: 8887 KDDGGADITGYILE--RRE-------PDQFR-WTRVTSTLSSPRYAVTGLKDGRSYLFRV 8936 Query: 588 RTENSHGLSGPSPVSDSVTV 607 R + +G S P D++ + Sbjct: 8937 RAVSKYGESEPLETEDAILI 8956 Score = 76.6 bits (180), Expect = 4e-12 Identities = 94/318 (29%), Positives = 135/318 (42%), Gaps = 40/318 (12%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 P P++P VT+ SVTLSWS G S + Y VE RE + WV Sbjct: 5669 PDAPSRPDIKKVTENSVTLSWSPPESDGGSPVTSYIVE--RREP--------DRDYWVKA 5718 Query: 564 ARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSN 622 R + T + V+ L P Y F V EN GL G S S SV + ++ V Sbjct: 5719 TRYPITDTTFTVQDLTPKHKYEFRVIAENKAGLGGASEASKSVI----AKPPYDVPDVPV 5774 Query: 623 STEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKT 682 + N +T + EL P+D I N Y +E D + + T Sbjct: 5775 DLDVTN--ITKNSAELFWNPPMDDGGSP----ITN-YVVE-------MKDKFGVRW---T 5817 Query: 683 ILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSR---VAQTLDDVPDGPPINIE 739 L + F++T+L+ ++YEF + K EG+P S VA+ DVPD P E Sbjct: 5818 SLGKPTKTSFKVTNLKTGSEYEFQVRAENKAGEGEPIQSTKPIVAKDAYDVPDAPE-KPE 5876 Query: 740 MFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTN 799 L T+V L WSPP ITGY +V + + + A +H+ T+L + + Sbjct: 5877 PSSLTETSVTLTWSPPASD-GGSQITGY--IVEKKEDFMTRWVNATRDAIHK-TTLTLND 5932 Query: 800 LTSGVSYSVQIAAETIIG 817 L G Y+ ++ AE G Sbjct: 5933 LREGSEYTFRVIAENKAG 5950 Score = 67.7 bits (158), Expect = 2e-09 Identities = 91/370 (24%), Positives = 152/370 (41%), Gaps = 41/370 (11%) Query: 495 FRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTP 554 F A +P P+ P ++T +S+TLSW G S++ GY VE RE+ G Sbjct: 7166 FTAKAQYGVPDAPSPPSVSDITPSSMTLSWEPPASDGGSTVTGYIVE--KRESPVGR--- 7220 Query: 555 RNSRGWVVIARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNS 613 WV + R + +T + V L Y F V EN+ G+ PS V++ + S Sbjct: 7221 -----WVPVNRAPIKETTFKVNDLSEDRKYEFRVSAENAAGVGKPS----EVSLPRVAKS 7271 Query: 614 LWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDN 673 ++ N T+ ++E A D + I N Y +E D Sbjct: 7272 PYDAPSAPGRPTATNVDSTELVLEWT-APVADGGS-----PITN-YVIEAR-------DK 7317 Query: 674 ITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN---SRVAQTLDDV 730 + + D + F++T L+ +Y+F +I K G+PS+ S VA+ D Sbjct: 7318 FGLRWSKINRQTVTDTT-FKVTGLKPNDEYQFRVIAENKVGLGRPSDNTESIVAKPPYDT 7376 Query: 731 PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH 790 PD P ++++ ++ L+WSPP +TGY V D + +N Sbjct: 7377 PDAPE-SVQVTGTTASSASLEWSPP-FSDGGSPVTGY--FVERKD-QYSARWTRVNRVPV 7431 Query: 791 QATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSI 850 T++++ +L G+ Y ++ AE G+G S + V D S P+ ++ Sbjct: 7432 TETNMVVGDLKEGLQYQFRVCAENRAGIGRSSDSTKPTVIKDPV--DAPSA-PLEPTIAS 7488 Query: 851 VAGDFVMETW 860 + D TW Sbjct: 7489 ITADSATLTW 7498 Score = 66.1 bits (154), Expect = 6e-09 Identities = 76/313 (24%), Positives = 127/313 (40%), Gaps = 28/313 (8%) Query: 6 VTSGEAPYIIEQPLDVTVARHQP-ATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPA 63 +T E P + PL A AT C P + W KG VV SD ++ + + Sbjct: 502 LTVNEKPLEVLSPLTKLFAYLTGNATFECEVS-EPWANVTWLKGDKEVVPSDKYK--MES 558 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE--PESKQSAQ 121 G F G D Y C + + +A L +LRE ++ PE + S + Sbjct: 559 DGRFRRMIIQGIAEDDVSDYTCVLRD-----KKTSADL---LLRETIKITKPPEDEDSRE 610 Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG---NLVIQDARQTDAGRY 178 +V C + + +V WKK GQ + D R +++ G LVI+D +DAG+Y Sbjct: 611 RQSVKFVCELTGDAAKADVKWKKGGQVV--RKDKRHKIINEGLVSTLVIEDLSPSDAGKY 668 Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL---- 234 + N ++ LK P T P+ V Q G S F+ + G P+P++ Sbjct: 669 SVLVDNMEMPFTLSVQALK---PPVFTTKPKAVDTQEGMSAIFRYVIAGYPVPEIKFTKD 725 Query: 235 WRR-SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293 W+ + ++ + + + V D G+Y A+N G V + + V P Sbjct: 726 WKEITPENSDVTFQFDEATQEHKVIFHEVTPKDAGKYLVIAKNESGEVKQAVSMMVTPRP 785 Query: 294 SINLSPNSVNVES 306 L +++++ Sbjct: 786 PEELMKRKMSLKA 798 Score = 65.7 bits (153), Expect = 7e-09 Identities = 122/506 (24%), Positives = 194/506 (38%), Gaps = 45/506 (8%) Query: 112 LEPESKQSAQ-GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVI 167 +EP SA+ G V LEC +P V W K+G + G R++ + G + + Sbjct: 9067 VEPLKDVSAKAGKIVTLECRI--SNPNAEVKWMKDGFQIF--GYDRVNEIKEGQRRAITL 9122 Query: 168 QDARQTDAGRYQC-IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVG 226 ++ D G+Y C + + S A I +K Y + VV +TG+++ Sbjct: 9123 RNVGDRDTGKYSCECGKQSTSCWLSVTAPPTIDVKAY----KDVVVVKTGNTLRLLVPYT 9178 Query: 227 GDPLPDVLWRR-SAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSAS 284 G P P V W R A ++ D+ + + + NV+ D G++S N G +A Sbjct: 9179 GCPSPKVEWHRHDARISEDTRTHIETRDNRTQITIRNVVRGDTGKFSITLTNEAGQETAI 9238 Query: 285 GYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344 + V D P P + +E +V R + + P S + T+ +R + Sbjct: 9239 IRVNVIDVP----GPPTGPLEITDVGRHCVSLSWEPPKDDGGSPIQSYTVEQREANRRMW 9294 Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSA-VNYAGSSFVRGKLTVTSDDDRPPPIITNG 403 + + + T++ + VC+ +N G + G V P Sbjct: 9295 TSVSNYVSHVPFTVSGLSEKVEYEFRVCAENINGVGPP-LHGIEPVVIVAPYSVPTPPGK 9353 Query: 404 PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSG 463 P + M + EP + I R N + V +DL K Sbjct: 9354 PEISNVQRDRM------TLTWSEPSHDGGKPIQGYIIERRENFSKQWNRVNRDLIKDT-- 9405 Query: 464 TYTCVASSRHGKYVWSGALLVDSPI-NP---NIHFFRAADVSSLPGPPTKPITHNVTDTS 519 T+T + Y + + + D+ I NP + A + P PP PI ++T TS Sbjct: 9406 TFTIKGLTEGSNYEFRISAVNDTGIGNPSEVSAPPKLARSPAGRPTPPGAPIIGDITATS 9465 Query: 520 VTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIP 579 V+LSWS + G S I Y VE L G S W + VH T V +L+ Sbjct: 9466 VSLSWSAPSTDGGSEITHYIVE----RRLKG------SYMW-IDRTVVHDTSCSVNNLVE 9514 Query: 580 GITYMFIVRTENSHG-LSGPSPVSDS 604 Y F V N+ G S PS S+S Sbjct: 9515 DKEYTFRVTAVNAAGNESDPSRASES 9540 Score = 65.3 bits (152), Expect = 1e-08 Identities = 96/380 (25%), Positives = 161/380 (42%), Gaps = 50/380 (13%) Query: 108 EEFRLEPESKQSA--QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN- 164 EE++ E K + +GDT L C V W K+G+ L + L + G Sbjct: 329 EEWKFTEELKPAKGFKGDTCELVC--EVNDENAIVEWVKHGKVL--KPSDKYELKEDGTK 384 Query: 165 --LVIQDARQTDAGRYQC-IARNAAGTRESAIATLKI--HIKPYLITGPEDVVAQTGSSV 219 LVI+DA D RY C + + G +KI +KP IT E V Sbjct: 385 RILVIKDAVPVDGARYTCQLPKTKTGASLDVQIPVKIVGDLKPLTITERETAV------- 437 Query: 220 TFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAEN 276 C V V W + ++ L + +VLD+G LR+ N+ D EY+C+ Sbjct: 438 -LTCEVSNTKAA-VTWLKDGEPIDITLDKYEVLDEGRRKKLRIKNISPEDAAEYTCQLPR 495 Query: 277 SVGAVSASGYLTVYDPPSINLSPNSVNVE--SGNVARFTCTATGRPEPTMFWSVEGNRTI 334 S S++ LTV + P LSP + +GN A F C + P + W ++G++ + Sbjct: 496 S----SSTMTLTVNEKPLEVLSPLTKLFAYLTGN-ATFECEVS-EPWANVTW-LKGDKEV 548 Query: 335 IFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394 + P + K + F + + I + D +D T V + +R + +T Sbjct: 549 V-PS-DKYKMESDGRFRRMIIQGIAEDDVSDY--TCVLRDKKTSADLLLRETIKIT---- 600 Query: 395 RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---T 451 +PP + S + +K + A + + W G+ + ++ R + N+G T Sbjct: 601 KPPE---DEDSRERQSVKFVCELTGDAA---KADVKWKKGGQVVRKDKRHKIINEGLVST 654 Query: 452 LVLKDLDKSDSGTYTCVASS 471 LV++DL SD+G Y+ + + Sbjct: 655 LVIEDLSPSDAGKYSVLVDN 674 Score = 65.3 bits (152), Expect = 1e-08 Identities = 84/325 (25%), Positives = 133/325 (40%), Gaps = 38/325 (11%) Query: 495 FRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTP 554 F A +PG P+ P+ +++ TS TLSWS G S I Y +E+ Sbjct: 4579 FIAKPPYDVPGAPSTPVASDISPTSATLSWSPPYSDGGSPITSYTIEM----------KD 4628 Query: 555 RNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSL 614 R S W V + + + SL Y F V EN G PSP TV + Sbjct: 4629 RFSSRWTKAKDMVTEETFQLNSLKENNEYQFRVIAENKAGPGEPSP-----TVNVTAKYE 4683 Query: 615 WEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNI 674 ++ + R T VEL P K+ I+ ++G P + Sbjct: 4684 FDTPQAPAEPDVRRTSPTS--VELSWVKPKSDGGSKIKGYIIE-KKVKG-----EPWTQV 4735 Query: 675 TIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGP 734 T + T+ D + F + L + EF + K G PSN+ V + P GP Sbjct: 4736 TTD----TV----DGTSFTVRGLPEDEDVEFRISAVNKAGAGSPSNTVV---IAFKPPGP 4784 Query: 735 PINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATS 794 P E+ ++ T+V L W+PP+L + +I GY +V + ++ V IN + + + Sbjct: 4785 PGTPEVSDVDKTSVTLTWTPPKLDGGSKVI-GY--IVEKREKGRDR-WVRINRSPVREVT 4840 Query: 795 LIMTNLTSGVSYSVQIAAETIIGLG 819 + +T+L Y ++ AE +G G Sbjct: 4841 MSITDLVEKNEYEFRVIAENKVGPG 4865 Score = 61.3 bits (142), Expect = 2e-07 Identities = 80/310 (25%), Positives = 127/310 (40%), Gaps = 27/310 (8%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSD 79 +T+ + A L C + + A+ W K G + ++ +L G LR + D Sbjct: 428 LTITERETAVLTCEVSNTKA-AVTWLKDGEPIDITLDKYEVLDEGRRKKLRIKNISPE-D 485 Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDTVVLECLPPRGSPEP 138 A Y C+ S T TL V E L P +K A EC P Sbjct: 486 AAEYTCQLPRSSSTM-----TLTVNEKPLEV-LSPLTKLFAYLTGNATFEC--EVSEPWA 537 Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196 NV W K + ++ +M DG ++IQ + D Y C+ R+ + SA L Sbjct: 538 NVTWLKGDKEVVPSDKYKMES-DGRFRRMIIQGIAEDDVSDYTCVLRDK---KTSADLLL 593 Query: 197 KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRRSAGGGNMPLGRVKVLDDG 255 + IK + PED ++ SV F C + GD DV W++ G R K++++G Sbjct: 594 RETIK--ITKPPEDEDSRERQSVKFVCELTGDAAKADVKWKKG-GQVVRKDKRHKIINEG 650 Query: 256 ---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARF 312 +L ++++ +D G+YS +N + S + PP P +V+ + G A F Sbjct: 651 LVSTLVIEDLSPSDAGKYSVLVDNMEMPFTLS--VQALKPPVFTTKPKAVDTQEGMSAIF 708 Query: 313 TCTATGRPEP 322 G P P Sbjct: 709 RYVIAGYPVP 718 Score = 60.9 bits (141), Expect = 2e-07 Identities = 45/180 (25%), Positives = 79/180 (43%), Gaps = 8/180 (4%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P + +P + VA + T+ C+ G P+P +RWY+ G + I G + L A Sbjct: 9994 PQFVSKPQNAHVAEGKSVTVTCQVSGYPAPEVRWYRLGREIAHGRKFQIGGDGNIHTLTA 10053 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GDTVVLE 128 D G TN GT L+V V+ + L + G+ ++L+ Sbjct: 10054 NQ-LFPEDVGEISVTVTNKGGTITDA-FELNVLVM-PKLTLPARLRTPIHLLLGEYIMLK 10110 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAG 187 +P G+P P++ W ++G+ ++ G + L+I+ + DAG+Y +A N G Sbjct: 10111 -VPFSGTPRPSIKWDRDGEDVVDGGRFEIKATPHDTTLIIRGITKEDAGKYSVVASNELG 10169 Score = 59.3 bits (137), Expect = 6e-07 Identities = 85/328 (25%), Positives = 133/328 (40%), Gaps = 45/328 (13%) Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRG-WV 561 +PGPP +P NV T++T+SW+ G S + GY +E SRG WV Sbjct: 1915 VPGPPAQPTCENVNKTTITVSWTPPEDDGGSPVTGYVIERCDV-----------SRGRWV 1963 Query: 562 VIAR-RVHQTHYVVKSLIPGITYMFIVRTENSH--GLSGPSPVSDSVTVGDDSNSLWEGT 618 R +V + + V L G Y F + EN+ G P+ + + + D+ Sbjct: 1964 KCNRDKVTELTFTVSDLTDGGQYQFRISAENAAGVGQPSPTSATFTAKLPFDAPG---AP 2020 Query: 619 GVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEY 678 G TEY +T I TP +S + + +E +T E Sbjct: 2021 GKPQVTEYNITKMT------ITWTPPESDG----GSPVTGFVVERKEKTSSRWVRVTKET 2070 Query: 679 EMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEG---KPSNSRVAQTLDDVPDGPP 735 +T L +T L + ++Y+F +I G +PS+ + A+ DVP P Sbjct: 2071 VTETTL--------TVTGLTEGSEYQFRVIAENLAGPGPASEPSDLQKAKLPFDVPTAPG 2122 Query: 736 INIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSL 795 ++ + T + L W+ PE ITGY + K AI T V + T+ Sbjct: 2123 -KPDITSADKTEMELTWTIPESD-GGSPITGYTIEKK---EKTGKWTKAIKTVVTETTTT 2177 Query: 796 IMTNLTSGVSYSVQIAAETIIGLGPFSQ 823 + T L Y ++AA + G GPFS+ Sbjct: 2178 V-TKLIEKKEYQFRVAAINLAGTGPFSE 2204 Score = 58.8 bits (136), Expect = 8e-07 Identities = 90/376 (23%), Positives = 152/376 (40%), Gaps = 45/376 (11%) Query: 444 RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSL 503 R + N+ T+ + DL + + + +A ++ G P NP+I F A + Sbjct: 4145 RTLVNETTMTVSDLVEKNDYEFRVIAENKVGP---------GEPSNPSIKFVAKAPFD-V 4194 Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 P P P NVT T+ TL+W+ + G S I GY +E+ R +R V Sbjct: 4195 PAAPDAPEPSNVTPTTATLTWTPPKRDGGSPITGYILEMKDRFA---------TRWTQVN 4245 Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNS 623 + + +K+L G Y F V N G S PS +++V + + Sbjct: 4246 TDSMTEVTCTLKTLKEGTEYQFRVIAVNKAGQSKPS--AETVVIAKHPFDVPGAPSTPTI 4303 Query: 624 TEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTI 683 T+ T + + L P + + + YY+E + +RP + + +K Sbjct: 4304 TK-----ATPNSISLAWRPPKVNGGSR-----VTGYYIE-MKDEYRPRWSPINKVAIKD- 4351 Query: 684 LHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFIL 743 + +++ L K KY F + K +GKPS A T D P I+ ++ + Sbjct: 4352 ------TDYKVMDLTKNEKYYFRVKAENKAGQGKPSLDTKA-TAKYPFDAPTID-DVSRI 4403 Query: 744 NTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSG 803 + T+ +KW+PP I+GY ++ D A K I T+ TS + NL G Sbjct: 4404 SETSAKIKWTPPSND-GGAEISGY--IIEKKDRLAVKWSPVIEDTLDN-TSFTVKNLREG 4459 Query: 804 VSYSVQIAAETIIGLG 819 +++A G G Sbjct: 4460 EDVEFRVSAVNKAGTG 4475 Score = 58.8 bits (136), Expect = 8e-07 Identities = 103/443 (23%), Positives = 166/443 (37%), Gaps = 42/443 (9%) Query: 178 YQCIARNAAGTRE-SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV----GGDPLPD 232 ++ +A+N AG + S++AT I KP D+ T +SVT GG P+ Sbjct: 5645 FRVVAKNKAGASQPSSVATFSI--KPPDAPSRPDIKKVTENSVTLSWSPPESDGGSPVTS 5702 Query: 233 VLWRRSAGGGNMPLGRVKV-LDDGSLRLDNVILADEGEYSCEAENSVGAVSAS-GYLTVY 290 + R + + + + D + + ++ + E+ AEN G AS +V Sbjct: 5703 YIVERREPDRDYWVKATRYPITDTTFTVQDLTPKHKYEFRVIAENKAGLGGASEASKSVI 5762 Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350 P ++ V+++ N+ + + P S N + +DK+ Sbjct: 5763 AKPPYDVPDVPVDLDVTNITKNSAELFWNPPMDDGGSPITNYVVEM----KDKFGVRWTS 5818 Query: 351 DGV-TVLTINDTD-KNDSRNTIVCSAVNYAGSSF-VRGKLTVTSDDDRPPPIITNGPSNQ 407 G T + T+ K S A N AG ++ + + D P P Sbjct: 5819 LGKPTKTSFKVTNLKTGSEYEFQVRAENKAGEGEPIQSTKPIVAKDAYDVPDAPEKPEPS 5878 Query: 408 TLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG----TLVLKDLDKSDS 462 +L S+ + + A I + E + N T D TL L DL + Sbjct: 5879 SLTETSVTLTWSPPASDGGSQITGYIVEKKEDFMTRWVNATRDAIHKTTLTLNDLREGSE 5938 Query: 463 GTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTL 522 T+ +A ++ G+ S P P F+A +P P P N+T+TS TL Sbjct: 5939 YTFRVIAENKAGQSKPS------EPCRP----FKAKKPYGVPDTPGSPEASNITETSATL 5988 Query: 523 SWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGI 581 +W G S I Y++E RE SG W R V +T + V+ L G Sbjct: 5989 NWKAPTSDGGSPITNYEIE--KREGASGR--------WTTCNRFDVSETSFTVRDLRAGH 6038 Query: 582 TYMFIVRTENSHGLSGPSPVSDS 604 Y F V N G PS S++ Sbjct: 6039 EYSFRVAAVNKAGSGKPSVPSET 6061 Score = 58.4 bits (135), Expect = 1e-06 Identities = 87/331 (26%), Positives = 139/331 (41%), Gaps = 40/331 (12%) Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562 LPGPP P +N +D SV L W+ + G + I+GY +E E N WV Sbjct: 5372 LPGPPGTPEVYNPSDKSVDLRWTPPTEQGGTRIIGYFIE--KCEVGKDN--------WVR 5421 Query: 563 IAR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVS 621 I R + + +YVV L + F V EN G+ PS S+SV + L S Sbjct: 5422 INRSSIREANYVVGDLTLNCRFKFRVCAENRAGVGPPSDYSESVLI-----KLPYDVPES 5476 Query: 622 NSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMK 681 T +++ D +V I P S + E Y +E Y +T K Sbjct: 5477 PDTPKISDVTNDSMV--ISWQPPYSDGGSKVTE----YIIEKKEPYSSKWVPVT-----K 5525 Query: 682 TILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGK---PSNSRVAQTLDDVPDGPPINI 738 T D+S ++IT L++ YEF + K + P+ S A+ DVP P ++ Sbjct: 5526 T----RDLS-YKITGLKENGDYEFRVAAVNKAGASEFSVPTPSTKAKLPYDVP-SQPHSL 5579 Query: 739 EMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMT 798 ++ ++ T++ L+WS P+ + ++GY ++ D + +N T T +T Sbjct: 5580 KIADVSPTSLTLEWSEPDSDGGDN-VSGY--IIEKKD-RFSPRWTPVNQTAISDTKFKVT 5635 Query: 799 NLTSGVSYSVQIAAETIIGLGPFSQKVYFNI 829 L G ++ A+ G S F+I Sbjct: 5636 GLKDGQDCEFRVVAKNKAGASQPSSVATFSI 5666 Score = 57.6 bits (133), Expect = 2e-06 Identities = 52/190 (27%), Positives = 83/190 (43%), Gaps = 30/190 (15%) Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480 TP P ++W G+ + +++R + ++ TL + +++DSG Y AS++ G+ Sbjct: 8496 TPTPTVSWTQNGDTVQKSNRITIDSNNYGTTLTARTAERTDSGDYVIRASNKAGEDT--- 8552 Query: 481 ALLVDSPINPNIHFFRAADVSSLPGPPTKPITH-NVTDTSVTLSWSQNNKIGSSSILGYQ 539 V +N V P PP P+ + VTLSWS+ G S I GY Sbjct: 8553 ---VTVTVN----------VVDSPSPPQGPLALVKLGSNEVTLSWSRPRDDGGSPITGYV 8599 Query: 540 VEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599 +E RE G+ W ++ ++ T + V L Y F VR EN+ G+S P Sbjct: 8600 LE--KREGGYGS--------WTNVSSKIPDTTFRVTKLTEDREYQFRVRAENNLGVSEPL 8649 Query: 600 PVSDSVTVGD 609 + GD Sbjct: 8650 ESERIIPKGD 8659 Score = 56.8 bits (131), Expect = 3e-06 Identities = 35/104 (33%), Positives = 50/104 (48%), Gaps = 11/104 (10%) Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562 +PGPP+KP T N+ T++T++W+ G S + GY VE E G WV Sbjct: 2217 VPGPPSKPTTENINKTTITITWTPPENDGGSPVTGYIVE--KCEGARGR--------WVK 2266 Query: 563 IAR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605 + V + + L G Y F V EN+ G+ P P SD+V Sbjct: 2267 CNKDLVTELTLTISDLHEGNDYQFRVSAENAAGVGQPGPPSDTV 2310 Score = 56.4 bits (130), Expect = 4e-06 Identities = 40/132 (30%), Positives = 67/132 (50%), Gaps = 9/132 (6%) Query: 688 DVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTT 747 D + F I L++ + EF ++ K GKPS + V L P GPP + + + T+ Sbjct: 5038 DDTNFTIKGLKEGEEAEFRVVAVNKAGSGKPSQTTVLAAL---PPGPPESPSISDVKQTS 5094 Query: 748 VHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYS 807 V L W+PPE + II GY +V D+ V +N + + T++++T+L Y Sbjct: 5095 VTLSWTPPESDGGSKII-GY--IVEKKDM---GRWVKVNRSPVRETTMVVTDLVEKSEYE 5148 Query: 808 VQIAAETIIGLG 819 ++ AE +G+G Sbjct: 5149 FRVMAENKVGVG 5160 Score = 55.6 bits (128), Expect = 8e-06 Identities = 84/319 (26%), Positives = 133/319 (41%), Gaps = 43/319 (13%) Query: 507 PTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARR 566 P+ P N+T S+TL+W+ G S I GY +E RE P S GW V+ R Sbjct: 6876 PSTPDVSNITGESMTLNWTAPRTDGGSPITGYVIE--KRE-------PGRS-GWTVVNRS 6925 Query: 567 -VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTE 625 + VV +L G Y F V EN GL PS V+ T + + G+ + E Sbjct: 6926 PITSLSCVVPNLRQGAEYEFRVIAENKAGLGRPSQVTHPFT----AKPPYTTPGIPDQPE 6981 Query: 626 YRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILH 685 VE + AT TI + W + Y G I +++ + + M+ + Sbjct: 6982 ----------VEDVTAT-----TITISWSPPS--YDGGSKITGYTIESKS-DATMRWVKI 7023 Query: 686 SNDVSGFEITS--LRKYTKYEFFLIPFYKKFEG---KPSNSRVAQTLDDVPDGPPINIEM 740 + V T+ L++ ++Y+F + K G KPS + D P PP ++ Sbjct: 7024 ESTVPDTTYTAARLKELSEYQFRVAAINKAGRGDFSKPSRPVTCKPPYD-PPPPPDAPDV 7082 Query: 741 FILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNL 800 + + T+ L WS P Q ITGY V++ D + + V + T + L Sbjct: 7083 YNITPTSAALTWSTPR-QDGGSPITGY--VIDKKDKYSTR-WVKADEVPAGTTDFTIKGL 7138 Query: 801 TSGVSYSVQIAAETIIGLG 819 +G Y +++A G+G Sbjct: 7139 QAGNDYEFRVSAVNAAGVG 7157 Score = 55.6 bits (128), Expect = 8e-06 Identities = 89/344 (25%), Positives = 129/344 (37%), Gaps = 49/344 (14%) Query: 267 EGEYSCEAENSVGAV---SASGYLTVYDP-----PSINLSPNSVNVESGNVARFTCTATG 318 E E+ AENS+GA + S + V DP P P + +V G TC +G Sbjct: 9960 EYEFRVMAENSMGASEPSTVSQRVLVRDPIDTVPPQFVSKPQNAHVAEGKSVTVTCQVSG 10019 Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378 P P + W G ++ + + LT N D I + N Sbjct: 10020 YPAPEVRWYRLGRE------IAHGRKFQIGGDGNIHTLTANQLFPEDV-GEISVTVTNKG 10072 Query: 379 GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438 G+ +L V P P + L M P + TP P I W +GE + Sbjct: 10073 GTITDAFELNVLVMPKLTLPARLRTPIHLLLGEYIMLKVPFSG--TPRPSIKWDRDGEDV 10130 Query: 439 IQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFF 495 + R + +D TL+++ + K D+G Y+ VAS+ G S I NI Sbjct: 10131 VDGGRFEIKATPHDTTLIIRGITKEDAGKYSVVASNELGHDTCS--------IQVNI--- 10179 Query: 496 RAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPR 555 P P +T ++ L+W+ G S+I Y VE RE G T Sbjct: 10180 -----LRHPDSPRNLECLEITSEAIRLAWNPPIYDGGSNISSYMVE--KREV--GVLT-- 10228 Query: 556 NSRGWV-VIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598 W VI+ + TH+ V +L Y F V N +G S P Sbjct: 10229 ----WARVISSK--NTHHTVINLRSDTQYQFRVTAFNMYGASEP 10266 Score = 54.8 bits (126), Expect = 1e-05 Identities = 38/103 (36%), Positives = 47/103 (45%), Gaps = 13/103 (12%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 PGPP P +V TSVTLSW+ G S I+GY VE ++ WV + Sbjct: 5079 PGPPESPSISDVKQTSVTLSWTPPESDGGSKIIGYIVE------------KKDMGRWVKV 5126 Query: 564 ARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605 R V +T VV L+ Y F V EN G+ PS S V Sbjct: 5127 NRSPVRETTMVVTDLVEKSEYEFRVMAENKVGVGEPSAPSSRV 5169 Score = 54.8 bits (126), Expect = 1e-05 Identities = 47/166 (28%), Positives = 70/166 (42%), Gaps = 21/166 (12%) Query: 37 GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96 G P P ++WY + H G+ L G D G Y E +N YG+ + Sbjct: 10811 GMPEPKVKWYHEDRPLKPGAHYHFYEEDGVHTLEID-GTTEKDKGQYTAEISNQYGSIAT 10869 Query: 97 RNATLHVAVL---------REEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147 + L V L + F L +G L+C G PEPN+ W K+ + Sbjct: 10870 K-CRLDVNELFLTKFKDYRKPHFDLHLRDIFIVEGSAARLDC-KVTGVPEPNIRWFKDHK 10927 Query: 148 TLLFDGDSRMHLVDGG------NLVIQDARQTDAGRYQCIARNAAG 187 +FDG + + ++ G +L+IQ+A DAG Y C+A N G Sbjct: 10928 E-IFDG--QHYSIEFGEDDETCSLIIQEAFLQDAGTYTCLASNLLG 10970 Score = 54.4 bits (125), Expect = 2e-05 Identities = 72/264 (27%), Positives = 107/264 (40%), Gaps = 27/264 (10%) Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408 V G+ L + D ++ DS T AVN G + ++ V DRP P GP + Sbjct: 9748 VVGGIAELYVKDAEREDS-GTYTLEAVNELGRHSITARVNVL---DRPGP--PQGPISIQ 9801 Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLD--KSDSGTYT 466 + A F T ++ ++ +++R + GT +L + K T+ Sbjct: 9802 SITNNSATFTWTLPLDDGGAPIQRYQ-VSIRESNRTHWQPLGTSLLPNFTAKKLKDNTHY 9860 Query: 467 CVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQ 526 + + +Y S L + I F D S PG PT N+ SV +SW+ Sbjct: 9861 VLRVTAENQYGTSRPLEIREAILVKSPF----DPPSAPGRPT---ISNIQRDSVHVSWTA 9913 Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMF 585 + G SSI GY +E R+T S+ W+ V T + + +L Y F Sbjct: 9914 PSSDGGSSITGYIIE--RRDT--------TSQRWIKANHEPVTTTSHTLINLREDTEYEF 9963 Query: 586 IVRTENSHGLSGPSPVSDSVTVGD 609 V ENS G S PS VS V V D Sbjct: 9964 RVMAENSMGASEPSTVSQRVLVRD 9987 Score = 54.0 bits (124), Expect = 2e-05 Identities = 81/324 (25%), Positives = 134/324 (41%), Gaps = 39/324 (12%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 PGPP P +V TSVTL+W+ G S ++GY VE RE + WV I Sbjct: 4782 PGPPGTPEVSDVDKTSVTLTWTPPKLDGGSKVIGYIVE--KRE--------KGRDRWVRI 4831 Query: 564 ARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSN 622 R V + + L+ Y F V EN G PS S+ + + + +E Sbjct: 4832 NRSPVREVTMSITDLVEKNEYEFRVIAENKVGPGEPSSPSERIV----AKAPYEVPSPPK 4887 Query: 623 STEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKT 682 S + + LT V L + P+ + ++ Y +E + N++ E+ + T Sbjct: 4888 SLKATD--LTPISVTLNWSAPLSNGGSPIVG-----YTIEMKDKFSTRWTNVS-EHMVTT 4939 Query: 683 ILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN--SRVAQTLDDVPDGP-PINIE 739 + + +L++ Y+F +I K G+PS S A+ + P+ P P +IE Sbjct: 4940 L-------SLNVPNLKEKNDYQFRVIAHNKAGPGQPSEPISVTAKFPFNAPEAPSPPSIE 4992 Query: 740 MFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTN 799 ++ T+V L WSPP +TGY ++ D + + + + T+ + Sbjct: 4993 R--ISPTSVKLAWSPPNSD-GGDKVTGY--IIEKKDRFSGR-WTPVTKDIIDDTNFTIKG 5046 Query: 800 LTSGVSYSVQIAAETIIGLGPFSQ 823 L G ++ A G G SQ Sbjct: 5047 LKEGEEAEFRVVAVNKAGSGKPSQ 5070 Score = 53.6 bits (123), Expect = 3e-05 Identities = 79/317 (24%), Positives = 113/317 (35%), Gaps = 35/317 (11%) Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562 LP P KP N+ +TL+WS G S I+GYQ+E R ++ R + Sbjct: 6371 LPDAPAKPDITNIDAKQITLAWSPPWSDGGSPIIGYQIEKKDRYSVRWTRATRET----- 6425 Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSN 622 +H Y ++ L G F V EN G+ GP + + + G Sbjct: 6426 ----IHDMQYTLRELTEGGEVEFRVAAENKAGV-GPFSETTGTVIAKSPFDVPSAPGTPK 6480 Query: 623 STEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKT 682 ++ L ++ TP S EI NF +E Y R + +KT Sbjct: 6481 ISDITGTSL------VLTWTPPSSDG---GTEITNF-IIELRDRYGR-WTRVNRTQVLKT 6529 Query: 683 ILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFI 742 GF + +L + YEF + K GKPS+S T P E I Sbjct: 6530 --------GFNVMNLSEGDSYEFRVTAENKMGVGKPSDSTQKVTAKPPYSQPAAPNEPQI 6581 Query: 743 LNTT--TVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNL 800 N T + L WSPP ITGY + P +N T + L Sbjct: 6582 SNVTADSATLTWSPPR-DDGGSSITGYFIEKKDKFSP---RWTRVNHDAVTDTKFTVPAL 6637 Query: 801 TSGVSYSVQIAAETIIG 817 G Y ++ A+ G Sbjct: 6638 VPGEEYQFRVVAQNKAG 6654 Score = 53.2 bits (122), Expect = 4e-05 Identities = 35/101 (34%), Positives = 47/101 (46%), Gaps = 9/101 (8%) Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562 +PGPP KP V TS+T++W+ G S + GY VE R+ +S SR V Sbjct: 2519 VPGPPGKPTILEVDSTSMTITWTPPETDGGSPVTGYVVE--KRDRVS-------SRWTKV 2569 Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603 + + Y + L G Y F V EN G+ PS SD Sbjct: 2570 KETSIEEVVYTIIDLKEGNDYQFRVSAENKAGVGKPSEPSD 2610 Score = 52.8 bits (121), Expect = 5e-05 Identities = 43/170 (25%), Positives = 67/170 (39%), Gaps = 14/170 (8%) Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGT---- 188 G PEP V W + L + DG + L I + D G+Y N G+ Sbjct: 10811 GMPEPKVKWYHEDRPLKPGAHYHFYEEDGVHTLEIDGTTEKDKGQYTAEISNQYGSIATK 10870 Query: 189 -----RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSA 239 E + K + KP+ D+ GS+ C+V G P P++ W + Sbjct: 10871 CRLDVNELFLTKFKDYRKPHFDLHLRDIFIVEGSAARLDCKVTGVPEPNIRWFKDHKEIF 10930 Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 G + + + + SL + L D G Y+C A N +G +S Y+ V Sbjct: 10931 DGQHYSIEFGEDDETCSLIIQEAFLQDAGTYTCLASNLLGRISCDSYVRV 10980 Score = 52.4 bits (120), Expect = 7e-05 Identities = 41/178 (23%), Positives = 76/178 (42%), Gaps = 16/178 (8%) Query: 171 RQTDAGRYQCIARNAAGTRESAIATLKIHIK-------PYLITGPEDVVAQTGSSVTFQC 223 R+ ++ +A N+ G E + + ++ ++ P ++ P++ G SVT C Sbjct: 9956 REDTEYEFRVMAENSMGASEPSTVSQRVLVRDPIDTVPPQFVSKPQNAHVAEGKSVTVTC 10015 Query: 224 RVGGDPLPDVLWRRSAGGGNMPLGR-VKVLDDG---SLRLDNVILADEGEYSCEAENSVG 279 +V G P P+V W R G + GR ++ DG +L + + D GE S N G Sbjct: 10016 QVSGYPAPEVRWYRL--GREIAHGRKFQIGGDGNIHTLTANQLFPEDVGEISVTVTNKGG 10073 Query: 280 AVSASGYLTVYDPPSINLSP---NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334 ++ + L V P + L +++ G +G P P++ W +G + Sbjct: 10074 TITDAFELNVLVMPKLTLPARLRTPIHLLLGEYIMLKVPFSGTPRPSIKWDRDGEDVV 10131 Score = 51.2 bits (117), Expect = 2e-04 Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 11/173 (6%) Query: 365 DSRNTIVCSAVNYAG--SSFVRGKLTVTSDDDRP--PPIITNGPSNQTLPIKSMAVFPCT 420 D T +AVN AG S R + ++ P P I N + +F C Sbjct: 9515 DKEYTFRVTAVNAAGNESDPSRASESFVAESQLPGAAPSILIEIQNAMVAEGQTGMFMCK 9574 Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGKYV 477 +P+P ++W G L+ + N+T D +V+ + ++G YT +A ++HG Sbjct: 9575 ISGSPKPKVSWMHHGRELMPGRKHNITEDNGVFKIVVFSVTDYETGMYTIIAKNKHGSVR 9634 Query: 478 WSGALLVDSPINPNIHFFR-AADVSSLPGPPTK-PITHNVTDTSVTLSWSQNN 528 S LL+ P P + R D+S G P+T T +W +++ Sbjct: 9635 SSAELLIQRP--PQLSIDRHLQDLSVRAGQEIHIPVTLTYGTPKPTFTWRRHD 9685 Score = 51.2 bits (117), Expect = 2e-04 Identities = 33/131 (25%), Positives = 61/131 (46%), Gaps = 7/131 (5%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---SLR 258 P ++ ++ + G + F C++ G P P V W G MP + + +D + Sbjct: 9552 PSILIEIQNAMVAEGQTGMFMCKISGSPKPKVSWMHH-GRELMPGRKHNITEDNGVFKIV 9610 Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN--SVNVESGNVARFTCTA 316 + +V + G Y+ A+N G+V +S L + PP +++ + ++V +G T Sbjct: 9611 VFSVTDYETGMYTIIAKNKHGSVRSSAELLIQRPPQLSIDRHLQDLSVRAGQEIHIPVTL 9670 Query: 317 T-GRPEPTMFW 326 T G P+PT W Sbjct: 9671 TYGTPKPTFTW 9681 Score = 50.4 bits (115), Expect = 3e-04 Identities = 71/332 (21%), Positives = 127/332 (38%), Gaps = 18/332 (5%) Query: 157 MHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT 215 +++V G L ++DA + D+G Y A N G R S A + + +P GP + + T Sbjct: 9746 VNVVGGIAELYVKDAEREDSGTYTLEAVNELG-RHSITARVNVLDRPGPPQGPISIQSIT 9804 Query: 216 GSSVTFQCRV----GGDPLP--DVLWRRSAGGGNMPLGRVKVLDDGSLRL-DNV--ILAD 266 +S TF + GG P+ V R S PLG + + + +L DN +L Sbjct: 9805 NNSATFTWTLPLDDGGAPIQRYQVSIRESNRTHWQPLGTSLLPNFTAKKLKDNTHYVLRV 9864 Query: 267 EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV-ARFTCTATGRPEPTMF 325 E + A + +DPPS P N++ +V +T ++ Sbjct: 9865 TAENQYGTSRPLEIREAILVKSPFDPPSAPGRPTISNIQRDSVHVSWTAPSSDGGSSITG 9924 Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385 + +E T + + H T++ + + + + R + +++ + S V Sbjct: 9925 YIIERRDTTSQRWIKAN--HEPVTTTSHTLINLREDTEYEFR-VMAENSMGASEPSTVSQ 9981 Query: 386 KLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN 445 ++ V D PP + P N + C P P + WY G + + Sbjct: 9982 RVLVRDPIDTVPPQFVSKPQNAHVAEGKSVTVTCQVSGYPAPEVRWYRLGREIAHGRKFQ 10041 Query: 446 VTNDG---TLVLKDLDKSDSGTYTCVASSRHG 474 + DG TL L D G + +++ G Sbjct: 10042 IGGDGNIHTLTANQLFPEDVGEISVTVTNKGG 10073 Score = 50.0 bits (114), Expect = 4e-04 Identities = 40/129 (31%), Positives = 67/129 (51%), Gaps = 7/129 (5%) Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751 F +T+++ + EF +I K EGKPS S V+ T +P GPP E++ + +V L+ Sbjct: 5336 FTVTNVQDDAECEFHVIAINKAGEGKPSPS-VSLTFR-LP-GPPGTPEVYNPSDKSVDLR 5392 Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811 W+PP Q II GY + +V + V IN + + + ++ +LT + ++ Sbjct: 5393 WTPPTEQGGTRII-GY--FIEKCEV-GKDNWVRINRSSIREANYVVGDLTLNCRFKFRVC 5448 Query: 812 AETIIGLGP 820 AE G+GP Sbjct: 5449 AENRAGVGP 5457 Score = 48.8 bits (111), Expect = 9e-04 Identities = 50/208 (24%), Positives = 81/208 (38%), Gaps = 19/208 (9%) Query: 444 RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSL 503 +++ D TL + DL + + + +A ++ G P NP+ F A Sbjct: 3171 KSLVKDTTLKVNDLTEKNQYEFRVIAENKVGP---------GEPSNPSARFTAKAPFDE- 3220 Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 P P ++T TS TLSW + G S ILGY +E R +SR V Sbjct: 3221 PEAPYSLAASDITPTSATLSWLPPDSDGGSPILGYTLETKDR---------FSSRWTKVN 3271 Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNS 623 + +T + V +L Y++ V EN G S PS + G V+ Sbjct: 3272 KGLLQETSFKVTNLEENNEYVYRVIAENKAGPSKPSNECKFIAKHQFETPEAPGNVVAKD 3331 Query: 624 TEYRNNILTDHIVELIEATPIDSKTIKL 651 T + ++T +PI T+++ Sbjct: 3332 TTPTSTVITWREPSFDGGSPITGYTVEM 3359 Score = 48.8 bits (111), Expect = 9e-04 Identities = 38/114 (33%), Positives = 47/114 (41%), Gaps = 10/114 (8%) Query: 493 HFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNN 552 H F A + PG P +P +VT T++T+SWS + G S I GY +E S T+ Sbjct: 6963 HPFTAKPPYTTPGIPDQPEVEDVTATTITISWSPPSYDGGSKITGYTIESKSDATMR--- 7019 Query: 553 TPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVT 606 WV I V T Y L Y F V N G S S VT Sbjct: 7020 -------WVKIESTVPDTTYTAARLKELSEYQFRVAAINKAGRGDFSKPSRPVT 7066 Score = 48.0 bits (109), Expect = 0.002 Identities = 34/97 (35%), Positives = 44/97 (45%), Gaps = 12/97 (12%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 PGPP P +V VTL+W+ G S+I+GY VE RE R W+ + Sbjct: 4095 PGPPGMPEVSDVDKNCVTLNWTPPTSDGGSTIIGYTVE--KRE---------KGRSWIRV 4143 Query: 564 ARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599 R V++T V L+ Y F V EN G PS Sbjct: 4144 NRTLVNETTMTVSDLVEKNDYEFRVIAENKVGPGEPS 4180 Score = 48.0 bits (109), Expect = 0.002 Identities = 73/329 (22%), Positives = 119/329 (36%), Gaps = 44/329 (13%) Query: 495 FRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTP 554 F+A + P P+ P+ VT SV LSW G S I+ Y VE ++ S T Sbjct: 6062 FKAQPPYAAPEAPSAPVIEEVTANSVKLSWEPPRLDGGSHIIDYVVE--KKDAFSIRWTE 6119 Query: 555 RNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSL 614 N R +T + V L G F V N G PS SVTV Sbjct: 6120 VN---------RTPETTFTVPKLKEGDAVQFRVTAVNKAGPGKPS--QSSVTV------- 6161 Query: 615 WEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNI 674 + A +D+ +I + W + Y + Sbjct: 6162 ----------TLKPEFTVPEAPSQPTAVEVDAVSITVRWSAPKNDGGSRITNYILEMKEQ 6211 Query: 675 TIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN------SRVAQTLD 728 + + + +++T L++ EF +I K EGKPS+ ++ T+ Sbjct: 6212 FSSFWKRVSTKESSELTYQVTGLKENQTLEFRVIAVNKAGEGKPSSVGGPFTTKATYTVP 6271 Query: 729 DVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTT 788 P P ++ + T++ + W+ + ITGY V+ DV + V +N Sbjct: 6272 SAPGAPDVS----NVKATSMTVTWT-KSISDGGSPITGY--VLEKCDVSTGR-WVPVNRV 6323 Query: 789 VHQATSLIMTNLTSGVSYSVQIAAETIIG 817 + TSL++ L Y ++ A + G Sbjct: 6324 PLRETSLVVDQLREKSEYCFRVVAHNVAG 6352 Score = 47.6 bits (108), Expect = 0.002 Identities = 35/108 (32%), Positives = 55/108 (50%), Gaps = 5/108 (4%) Query: 716 GKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLD 775 G PS++ A+ D P G P ++ N T + + WSPPE +TG+ VV + Sbjct: 2304 GPPSDTVKAKLPFDAP-GAPGKPQVTEYNITKMTITWSPPESD-GGSPVTGF--VVERKE 2359 Query: 776 VPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQ 823 +++ + TV + T+LI+T LT G Y ++ AE G GP S+ Sbjct: 2360 STSSRWVRVTKETVTE-TTLIVTGLTEGSEYQFRVIAENPAGPGPASE 2406 Score = 46.8 bits (106), Expect = 0.004 Identities = 72/267 (26%), Positives = 109/267 (40%), Gaps = 34/267 (12%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 P P+KP ++ TS ++W+ G S + GY VE RE + WV + Sbjct: 3504 PSAPSKPEVTDIQKTSAVVTWTAPKNDGGSQVTGYTVE--KRE--------KGRDQWVRV 3553 Query: 564 ARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSN 622 R+ V +T V L+ Y F V EN G S S S T + GV Sbjct: 3554 NRKPVTETTMKVPDLVEKNNYEFRVIAENRAGPGEASDASASFTAKAPFDEP-SAPGVPK 3612 Query: 623 STEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKT 682 ++ +T V L P DS + E Y LE Y +T + T Sbjct: 3613 ASN-----ITPTSVTLSWTAP-DSDGGSPITE----YILESKDKYSSKFSPVTRD----T 3658 Query: 683 ILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSR--VAQTLDDVPDGPPINIEM 740 + D++ F + +L++ +Y+F +I K +PS VA+ +VP P E+ Sbjct: 3659 V---TDLT-FTVKNLKENGEYQFRVIAQNKAGPSEPSRETKVVAKYEFEVPQAPSAP-EV 3713 Query: 741 FILNTTTVHLKWSPPELQLQNGIITGY 767 L+ T++ L W+PP ITGY Sbjct: 3714 RRLSPTSIQLDWTPPFAD-GGSDITGY 3739 Score = 46.8 bits (106), Expect = 0.004 Identities = 32/104 (30%), Positives = 48/104 (46%), Gaps = 11/104 (10%) Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV- 561 +P PP +P N+T SVTL+W+ + G S + GY VE R S WV Sbjct: 7775 VPSPPGEPTISNITAKSVTLNWTPPSSDGGSPVTGYTVE----------RADRFSTRWVP 7824 Query: 562 VIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605 V + + T + L +Y F + N+ G S P+ +DS+ Sbjct: 7825 VNSHPIKDTKMDIHDLPATGSYQFRIVACNAAGTSKPTSPTDSI 7868 Score = 46.8 bits (106), Expect = 0.004 Identities = 45/162 (27%), Positives = 68/162 (41%), Gaps = 10/162 (6%) Query: 112 LEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQD 169 +E ++ A+G T + C GSP+P V W +G+ L+ G D G +V+ Sbjct: 9556 IEIQNAMVAEGQTGMFMC-KISGSPKPKVSWMHHGRELM-PGRKHNITEDNGVFKIVVFS 9613 Query: 170 ARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP--EDVVAQTGSSVTFQCRVG- 226 + G Y IA+N G+ S+ A L I P L +D+ + G + + Sbjct: 9614 VTDYETGMYTIIAKNKHGSVRSS-AELLIQRPPQLSIDRHLQDLSVRAGQEIHIPVTLTY 9672 Query: 227 GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268 G P P WRR G GR + G R+ + L D G Sbjct: 9673 GTPKPTFTWRRHDGEELDTRGRYSTKEQG--RVHDFELPDLG 9712 Score = 46.4 bits (105), Expect = 0.005 Identities = 36/129 (27%), Positives = 63/129 (48%), Gaps = 8/129 (6%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEG---KPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHL 750 +T L + +Y+F + G +PS++++A+ DVP GPP +N TT+ + Sbjct: 2178 VTKLIEKKEYQFRVAAINLAGTGPFSEPSDNKMAKAPYDVP-GPPSKPTTENINKTTITI 2236 Query: 751 KWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQI 810 W+PPE +TGY +V + A V N + +L +++L G Y ++ Sbjct: 2237 TWTPPEND-GGSPVTGY--IVEKCE-GARGRWVKCNKDLVTELTLTISDLHEGNDYQFRV 2292 Query: 811 AAETIIGLG 819 +AE G+G Sbjct: 2293 SAENAAGVG 2301 Score = 46.4 bits (105), Expect = 0.005 Identities = 41/140 (29%), Positives = 63/140 (45%), Gaps = 7/140 (5%) Query: 688 DVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTT 747 D + F + +LR+ EF + K GKPS+ TL P GPP E ++ + Sbjct: 4447 DNTSFTVKNLREGEDVEFRVSAVNKAGTGKPSS---IATLAAKPPGPPGVPEASNIDKIS 4503 Query: 748 VHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYS 807 L W+PPE +TGY +V + ++ M +N + +L + +LT Y Sbjct: 4504 ATLTWTPPESD-GGSKVTGY--IVEKRERGLDRWM-KVNRAPVKDVTLKVLDLTEKKHYE 4559 Query: 808 VQIAAETIIGLGPFSQKVYF 827 ++ AE GLG S V F Sbjct: 4560 FRVTAENKAGLGEPSDSVSF 4579 Score = 46.0 bits (104), Expect = 0.006 Identities = 33/102 (32%), Positives = 45/102 (44%), Gaps = 9/102 (8%) Query: 505 GPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIA 564 G P+ P+ + T TSVTL W+ G S I GY +E +E S P S+ Sbjct: 7676 GRPSPPVVTDFTKTSVTLQWNPPESDGGSHITGYVLE--KKEAYSVRWFPCTSQS----- 7728 Query: 565 RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVT 606 + + + VK L G Y F V N G+ PS S+ T Sbjct: 7729 --ILKPEFTVKDLKEGAQYEFRVMALNKAGIGPPSDGSELAT 7768 Score = 45.6 bits (103), Expect = 0.008 Identities = 35/107 (32%), Positives = 46/107 (42%), Gaps = 11/107 (10%) Query: 495 FRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTP 554 F A +P P KP +++ TSVTL+W+ G S I GY VE+ Sbjct: 2916 FVAKPPYDVPDAPGKPAPSDLSPTSVTLTWTPPPSDGGSPITGYTVEM----------KD 2965 Query: 555 RNSRGWVVIARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600 + S W R + +T V+ L Y F V EN G S PSP Sbjct: 2966 KFSTRWTKATRELISETTVVLPDLKEKEEYQFRVIAENKAGQSKPSP 3012 Score = 45.6 bits (103), Expect = 0.008 Identities = 33/99 (33%), Positives = 43/99 (43%), Gaps = 10/99 (10%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 P PPT P ++ TSV L+WS G S + Y VE ++ SG TP V Sbjct: 3409 PKPPTPPEVKRLSPTSVQLNWSAPTSDGGSEVTAYIVE---KKDKSGRWTP-------VT 3458 Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602 + + T + VK L G F V N G PS V+ Sbjct: 3459 SDSIEDTSFTVKGLKEGEDVEFRVSAVNKAGTGKPSEVT 3497 Score = 45.6 bits (103), Expect = 0.008 Identities = 40/134 (29%), Positives = 64/134 (47%), Gaps = 8/134 (5%) Query: 693 EITSLRKYTKYEFFLIPFYKKFEGKPSNS---RVAQTLDDVPDGPPINIEMFILNTTTVH 749 +I+ L++ +Y+F ++ K + PSN +VA++ DVP+ P ++ + T+V Sbjct: 7536 KISGLKEGNEYQFRVVATNKAGQSAPSNPSQPKVAKSPYDVPEAPS-KPQVTEVKATSVT 7594 Query: 750 LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQ 809 LKW PP ITGY VV + A + +NTT T +T LT Y + Sbjct: 7595 LKWRPPGSD-GGSPITGY--VVQKKERLALR-WTPVNTTPVGDTIFTVTGLTQKSEYEFR 7650 Query: 810 IAAETIIGLGPFSQ 823 + A G G S+ Sbjct: 7651 VVAANKKGFGQPSE 7664 Score = 45.6 bits (103), Expect = 0.008 Identities = 88/401 (21%), Positives = 150/401 (37%), Gaps = 52/401 (12%) Query: 226 GGDPLPDVLWRRSAGGGNMPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVG---A 280 GG P+ + + N +V + G S R+ ++ +E E+ AEN G A Sbjct: 8097 GGAPISGYIIEKKETSSNY-WSKVTTVSSGVTSHRIPRLMRGEEYEFRVSAENRAGPGPA 8155 Query: 281 VSASGYLTVYD----PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF 336 + S + D P + + G R TG P P + WS +G Sbjct: 8156 STPSAPIRAEDTTVLPKFSGRFDEPIMAKVGESFRIEVPYTGIPTPAVTWSFDGRP---- 8211 Query: 337 PGMSRDKYHATAVFDGVTVLTINDTDK-NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395 + + + + +T+ + +K N R TI + N AG+ + ++ V DR Sbjct: 8212 --LKPSAHIRIDTSNRASTITVKNVEKANGGRYTI--NLKNTAGAESLDVEVRVF---DR 8264 Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTP--EPIIAWYFEGEALIQNHRRNVTNDG--- 450 P P GP + +S + I + + I+ ++V D Sbjct: 8265 PGP--PRGPLEMSNVSESTVTLSWSPPSDDGGSRIFTYVVQKRGEIETKWKHVNKDYIID 8322 Query: 451 -TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTK 509 T + L ++ + +A +++G+ L I P + ++P PP+ Sbjct: 8323 LTYKVTGLKENKKYQFRVLAENQYGQ----SKPLEGQSITPQGQY-------NVPDPPSA 8371 Query: 510 PITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV-VIARRVH 568 P N+ SVT+ W+ + G + + GY VE+ R+T S PR W+ Sbjct: 8372 PKVTNIIGDSVTVGWTPPSNDGGAPVTGYVVEM--RQTTS----PR----WIKATLTPTP 8421 Query: 569 QTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609 + LI G Y F V N G P S++V V D Sbjct: 8422 DMTFRASRLIRGTEYEFRVCAVNRAGTGRPGEPSNTVMVED 8462 Score = 45.2 bits (102), Expect = 0.011 Identities = 37/146 (25%), Positives = 64/146 (43%), Gaps = 9/146 (6%) Query: 683 ILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFI 742 + S D + F + L++ EF + K + KPS + P GPP E+ Sbjct: 4049 VTDSVDGTSFTVKGLKEGENVEFRVSAVNKAGQSKPSEVSLVAVK---PPGPPGMPEVSD 4105 Query: 743 LNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTS 802 ++ V L W+PP + II GY V +S + +N T+ T++ +++L Sbjct: 4106 VDKNCVTLNWTPPTSDGGSTII-GYTVEKR----EKGRSWIRVNRTLVNETTMTVSDLVE 4160 Query: 803 GVSYSVQIAAETIIGLG-PFSQKVYF 827 Y ++ AE +G G P + + F Sbjct: 4161 KNDYEFRVIAENKVGPGEPSNPSIKF 4186 Score = 44.8 bits (101), Expect = 0.015 Identities = 37/133 (27%), Positives = 67/133 (50%), Gaps = 8/133 (6%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEG---KPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHL 750 I SL + +YEF + G +PS+ ++A+ DVP GPP + +++T++ + Sbjct: 2480 IKSLIEKKEYEFRVAAVNLAGTGPFSEPSDYQIAKAPYDVP-GPPGKPTILEVDSTSMTI 2538 Query: 751 KWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQI 810 W+PPE +TGY VV D +++ T++ + I+ +L G Y ++ Sbjct: 2539 TWTPPETD-GGSPVTGY--VVEKRDRVSSRWTKVKETSIEEVVYTII-DLKEGNDYQFRV 2594 Query: 811 AAETIIGLGPFSQ 823 +AE G+G S+ Sbjct: 2595 SAENKAGVGKPSE 2607 Score = 44.8 bits (101), Expect = 0.015 Identities = 36/105 (34%), Positives = 45/105 (42%), Gaps = 9/105 (8%) Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562 +P P+KP V TSVTL W G S I GY V+ +E L+ TP N+ Sbjct: 7576 VPEAPSKPQVTEVKATSVTLKWRPPGSDGGSPITGYVVQ--KKERLALRWTPVNT----- 7628 Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607 V T + V L Y F V N G PS ++SV V Sbjct: 7629 --TPVGDTIFTVTGLTQKSEYEFRVVAANKKGFGQPSEPTNSVLV 7671 Score = 44.8 bits (101), Expect = 0.015 Identities = 30/137 (21%), Positives = 53/137 (38%), Gaps = 1/137 (0%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68 G AP I+ + + VA Q C+ GSP P + W G ++ +I G+F Sbjct: 9549 GAAPSILIEIQNAMVAEGQTGMFMCKISGSPKPKVSWMHHGRELMPGRKHNITEDNGVFK 9608 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128 + + G+Y A N +G+ RS L + + G + + Sbjct: 9609 I-VVFSVTDYETGMYTIIAKNKHGSVRSSAELLIQRPPQLSIDRHLQDLSVRAGQEIHIP 9667 Query: 129 CLPPRGSPEPNVYWKKN 145 G+P+P W+++ Sbjct: 9668 VTLTYGTPKPTFTWRRH 9684 Score = 44.4 bits (100), Expect = 0.019 Identities = 45/159 (28%), Positives = 63/159 (39%), Gaps = 19/159 (11%) Query: 450 GTLVLKDLDKSDSGTYTCVASSRHGKYVW----SGALLVDSPINPNIHFFRAADVSSLPG 505 G V + DK T+T + G+Y + A V P +P F A PG Sbjct: 1960 GRWVKCNRDKVTELTFTVSDLTDGGQYQFRISAENAAGVGQP-SPTSATFTAKLPFDAPG 2018 Query: 506 PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565 P KP T +T++W+ G S + G+ VE + S WV + + Sbjct: 2019 APGKPQVTEYNITKMTITWTPPESDGGSPVTGFVVE----------RKEKTSSRWVRVTK 2068 Query: 566 R-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603 V +T V L G Y F V EN L+GP P S+ Sbjct: 2069 ETVTETTLTVTGLTEGSEYQFRVIAEN---LAGPGPASE 2104 Score = 44.4 bits (100), Expect = 0.019 Identities = 31/104 (29%), Positives = 43/104 (41%), Gaps = 11/104 (10%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 P PP P +N+T TS L+WS + G S I GY ++ + S WV Sbjct: 7074 PPPPDAPDVYNITPTSAALTWSTPRQDGGSPITGYVID----------KKDKYSTRWVKA 7123 Query: 564 AR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVT 606 T + +K L G Y F V N+ G+ PS + T Sbjct: 7124 DEVPAGTTDFTIKGLQAGNDYEFRVSAVNAAGVGKPSAPCERFT 7167 Score = 44.0 bits (99), Expect = 0.025 Identities = 45/194 (23%), Positives = 75/194 (38%), Gaps = 14/194 (7%) Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ 168 +F +P++ A+G +V + C G P P V W + G+ + + + GN+ Sbjct: 9995 QFVSKPQNAHVAEGKSVTVTC-QVSGYPAPEVRWYRLGREIAHG--RKFQIGGDGNIHTL 10051 Query: 169 DARQT---DAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE---DVVAQTGSSVTFQ 222 A Q D G N GT A L + + P L + G + + Sbjct: 10052 TANQLFPEDVGEISVTVTNKGGTITDAFE-LNVLVMPKLTLPARLRTPIHLLLGEYIMLK 10110 Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGRVKVL---DDGSLRLDNVILADEGEYSCEAENSVG 279 G P P + W R G + GR ++ D +L + + D G+YS A N +G Sbjct: 10111 VPFSGTPRPSIKWDRD-GEDVVDGGRFEIKATPHDTTLIIRGITKEDAGKYSVVASNELG 10169 Query: 280 AVSASGYLTVYDPP 293 + S + + P Sbjct: 10170 HDTCSIQVNILRHP 10183 Score = 43.6 bits (98), Expect = 0.034 Identities = 32/101 (31%), Positives = 45/101 (44%), Gaps = 14/101 (13%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 PG P KP T +T++WS G S + G+ VE +E+ S WV + Sbjct: 2319 PGAPGKPQVTEYNITKMTITWSPPESDGGSPVTGFVVE--RKESTSSR--------WVRV 2368 Query: 564 ARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603 + V +T +V L G Y F V EN +GP P S+ Sbjct: 2369 TKETVTETTLIVTGLTEGSEYQFRVIAENP---AGPGPASE 2406 Score = 43.6 bits (98), Expect = 0.034 Identities = 41/159 (25%), Positives = 65/159 (40%), Gaps = 21/159 (13%) Query: 444 RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSL 503 R + ++ T+VL DL + + + +A ++ G+ S +P +H + Sbjct: 2976 RELISETTVVLPDLKEKEEYQFRVIAENKAGQ----------SKPSPELHVTAKYPFETP 3025 Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 P +T + TS T+ WS G S I GY +E +E +S PR W + Sbjct: 3026 QAPTIDNVTRE-SPTSATVKWSPPKSDGGSEITGYVLE--KKEKMS----PR----WSPV 3074 Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602 +T + VK L G F V N G PS V+ Sbjct: 3075 IESETETSFTVKGLPDGENVEFRVSAVNKAGTGKPSQVA 3113 Score = 43.6 bits (98), Expect = 0.034 Identities = 77/322 (23%), Positives = 123/322 (38%), Gaps = 35/322 (10%) Query: 499 DVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558 D P P +P ++T S TL+W ++ G S++ GY VE P +R Sbjct: 7473 DPVDAPSAPLEPTIASITADSATLTWIAPSRDGGSAVTGYIVE---------RKDPYTAR 7523 Query: 559 GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGT 618 W I R T+ + L G Y F V N G S PS S V + E Sbjct: 7524 -WTPI-ERCTDTNCKISGLKEGNEYQFRVVATNKAGQSAPSNPSQP-KVAKSPYDVPEAP 7580 Query: 619 GVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEY 678 TE + +T L P + ++ E L + + P++ + Sbjct: 7581 SKPQVTEVKATSVT-----LKWRPPGSDGGSPITGYVVQ--KKERLALRWTPVNTTPVGD 7633 Query: 679 EMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINI 738 + T V+G +T +Y EF ++ KK G+PS L P G P Sbjct: 7634 TIFT------VTG--LTQKSEY---EFRVVAANKKGFGQPSEP-TNSVLVKPPYGRPSPP 7681 Query: 739 EMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMT 798 + T+V L+W+PPE ITGY V+ + + + + ++ + + Sbjct: 7682 VVTDFTKTSVTLQWNPPESD-GGSHITGY--VLEKKEAYSVRWFPCTSQSILK-PEFTVK 7737 Query: 799 NLTSGVSYSVQIAAETIIGLGP 820 +L G Y ++ A G+GP Sbjct: 7738 DLKEGAQYEFRVMALNKAGIGP 7759 Score = 43.2 bits (97), Expect = 0.044 Identities = 31/100 (31%), Positives = 42/100 (42%), Gaps = 11/100 (11%) Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562 +P P+ P ++ TSV LSW+ G + I GY + ++ SG W Sbjct: 4000 IPQEPSAPEVKRLSPTSVELSWTPPRSDGGADITGY---ILEKKDKSGR--------WTP 4048 Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602 + V T + VK L G F V N G S PS VS Sbjct: 4049 VTDSVDGTSFTVKGLKEGENVEFRVSAVNKAGQSKPSEVS 4088 Score = 42.7 bits (96), Expect = 0.059 Identities = 36/117 (30%), Positives = 55/117 (47%), Gaps = 10/117 (8%) Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562 +P P+KP+ NVT SVTL W G + I GY +E +ET S N + + Sbjct: 8069 VPEAPSKPLVTNVTSDSVTLEWHSPKSDGGAPISGYIIE--KKET-SSNYWSKVT----T 8121 Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTG 619 ++ V T + + L+ G Y F V EN G GP+ + +D+ L + +G Sbjct: 8122 VSSGV--TSHRIPRLMRGEEYEFRVSAENRAG-PGPASTPSAPIRAEDTTVLPKFSG 8175 Score = 42.7 bits (96), Expect = 0.059 Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 12/86 (13%) Query: 253 DDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV----------YDPPSINLSPN 300 +DG +L +D D+G+Y+ E N G+++ L V Y P +L Sbjct: 10837 EDGVHTLEIDGTTEKDKGQYTAEISNQYGSIATKCRLDVNELFLTKFKDYRKPHFDLHLR 10896 Query: 301 SVNVESGNVARFTCTATGRPEPTMFW 326 + + G+ AR C TG PEP + W Sbjct: 10897 DIFIVEGSAARLDCKVTGVPEPNIRW 10922 Score = 42.3 bits (95), Expect = 0.078 Identities = 44/170 (25%), Positives = 78/170 (45%), Gaps = 11/170 (6%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSN---SRVAQTLDDVPDGPPINIEMFILNTTTVHL 750 + LR+ ++Y F ++ E KPS + +A+ +PD P ++ ++ + L Sbjct: 6332 VDQLREKSEYCFRVVAHNVAGESKPSEPSKAYIAKPPYGLPDAPA-KPDITNIDAKQITL 6390 Query: 751 KWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQI 810 WSPP + II GY + D + + A T+H + LT G ++ Sbjct: 6391 AWSPPWSDGGSPII-GYQIEKK--DRYSVRWTRATRETIHDM-QYTLRELTEGGEVEFRV 6446 Query: 811 AAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETW 860 AAE G+GPFS+ + ++S D+ S P ++S + G ++ TW Sbjct: 6447 AAENKAGVGPFSETT-GTVIAKS-PFDVPSA-PGTPKISDITGTSLVLTW 6493 Score = 41.1 bits (92), Expect = 0.18 Identities = 78/350 (22%), Positives = 133/350 (38%), Gaps = 37/350 (10%) Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNA 185 EC R + ++ W K+GQ + D ++ DG +L IQD D+G+Y + Sbjct: 1013 ECDVSRDVKDEDIVWMKDGQKITPDEKFQVKR-DGRRLSLSIQDTSPEDSGQYTIKIGDK 1071 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 T + + + +KP T A+ ++ +C + + +P ++ P Sbjct: 1072 TQTADLKVQAAEF-VKPLNNTS----AAEYDETIVLECELSNELVPCQWYKDDVLITVGP 1126 Query: 246 LGRVKVLDDGSLR---LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302 +V+V+DDG R L +V D G + C VG +S L V + Sbjct: 1127 --KVEVIDDGKKRKLVLHDVRPEDTGNFRC----VVGDKESSATLDVKASEIMKPLAEVT 1180 Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG-VTVLTINDT 361 E A C + P+ W +G + I ++ KY V DG L I+D Sbjct: 1181 APEFAETAVLECEVS-HPKAEATWLKDG-QPITPEELTSKKYE--VVSDGRKRRLIIHDV 1236 Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421 K+D+ C + + V K+ P IT + T ++ V C Sbjct: 1237 VKDDNAE-FTCKVGDNQTVANVNVKV----------PSITKPLEDTTTAFETTVVLECEV 1285 Query: 422 ICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCV 468 P + W G+ + + + + + G L + + D G YTCV Sbjct: 1286 DNEKAP-VKWMKNGKEITKMPKYLMESKGKKRRLTIFETIPEDEGDYTCV 1334 Score = 41.1 bits (92), Expect = 0.18 Identities = 37/134 (27%), Positives = 61/134 (45%), Gaps = 7/134 (5%) Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPS---NSRVAQTLDDVPDGPPINIEMFILNTTTV 748 + I L++ Y+F + K GKPS + R A+ DVP GPP ++ ++ + Sbjct: 2579 YTIIDLKEGNDYQFRVSAENKAGVGKPSEPSDQRRAKPPYDVP-GPPGIPDISDVDKNRM 2637 Query: 749 HLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSV 808 L W+PP I GY +V D + A + +L + +LT G +Y Sbjct: 2638 TLTWTPPTDD-GGAKILGY--IVEKCDADRKRWTKAHKEDLVTELTLTVYDLTEGTNYMF 2694 Query: 809 QIAAETIIGLGPFS 822 +++AE G+G S Sbjct: 2695 RVSAENAAGVGESS 2708 Score = 41.1 bits (92), Expect = 0.18 Identities = 33/97 (34%), Positives = 39/97 (40%), Gaps = 11/97 (11%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 PGPP P N+ S TL+W+ G S + GY VE RE R W+ + Sbjct: 4488 PGPPGVPEASNIDKISATLTWTPPESDGGSKVTGYIVE--KRE--------RGLDRWMKV 4537 Query: 564 ARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599 R V V L Y F V EN GL PS Sbjct: 4538 NRAPVKDVTLKVLDLTEKKHYEFRVTAENKAGLGEPS 4574 Score = 41.1 bits (92), Expect = 0.18 Identities = 34/143 (23%), Positives = 63/143 (44%), Gaps = 8/143 (5%) Query: 158 HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT--LKIHIKPYLITGP--EDVVA 213 H + + I D T + +++ +A NAAGT + T + + + P L T + +V Sbjct: 7828 HPIKDTKMDIHDLPATGSYQFRIVACNAAGTSKPTSPTDSIGMAVAPKLDTYKYHDTMVV 7887 Query: 214 QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LD-DGSLRLDNVILADEGEY 270 + G++ P P V W + G R+K+ D D + + N + DEG + Sbjct: 7888 RVGATFNLDVPFKATPKPTVKWTKD-GSTLQASSRIKIDTTDRDTIVTIKNCVREDEGSF 7946 Query: 271 SCEAENSVGAVSASGYLTVYDPP 293 + N+ G+ + + + V D P Sbjct: 7947 KLDVSNTAGSDAITIRVQVLDRP 7969 Score = 41.1 bits (92), Expect = 0.18 Identities = 44/168 (26%), Positives = 68/168 (40%), Gaps = 17/168 (10%) Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377 G PEP + W E + PG Y DGV L I+ T + D + N Sbjct: 10811 GMPEPKVKWYHEDRP--LKPGAHYHFYEE----DGVHTLEIDGTTEKD-KGQYTAEISNQ 10863 Query: 378 AGSSFVRGKLTV-----TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432 GS + +L V T D P + + S A C PEP I W+ Sbjct: 10864 YGSIATKCRLDVNELFLTKFKDYRKPHFDLHLRDIFIVEGSAARLDCKVTGVPEPNIRWF 10923 Query: 433 FEGEALIQNHRRNVT---NDGT--LVLKDLDKSDSGTYTCVASSRHGK 475 + + + ++ +D T L++++ D+GTYTC+AS+ G+ Sbjct: 10924 KDHKEIFDGQHYSIEFGEDDETCSLIIQEAFLQDAGTYTCLASNLLGR 10971 Score = 40.7 bits (91), Expect = 0.24 Identities = 36/137 (26%), Positives = 59/137 (43%), Gaps = 7/137 (5%) Query: 683 ILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFI 742 ++ S + F + L EF + K GKPS +VA TL P G P E+ Sbjct: 3074 VIESETETSFTVKGLPDGENVEFRVSAVNKAGTGKPS--QVA-TLSAKPPGAPDAPEVSD 3130 Query: 743 LNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTS 802 ++ T+ + W+ P L ITGY + +N ++ + T+L + +LT Sbjct: 3131 IDRTSATVIWTVPSLD-GGSTITGYTIERR---EKGRDRWTRVNKSLVKDTTLKVNDLTE 3186 Query: 803 GVSYSVQIAAETIIGLG 819 Y ++ AE +G G Sbjct: 3187 KNQYEFRVIAENKVGPG 3203 Score = 40.7 bits (91), Expect = 0.24 Identities = 31/100 (31%), Positives = 44/100 (44%), Gaps = 11/100 (11%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 PG P +P ++ TS T++W ++ G S+I GY VE RE + WV + Sbjct: 3800 PGAPGRPEVSDINKTSATVTWKPSSSDGGSTITGYIVE--KRE--------KGRDRWVPV 3849 Query: 564 ARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602 R+ ++ V L Y F V EN G PS S Sbjct: 3850 NRKPINAVTMKVTDLTEKTDYEFRVIAENRIGQGQPSEPS 3889 Score = 40.7 bits (91), Expect = 0.24 Identities = 39/136 (28%), Positives = 58/136 (42%), Gaps = 15/136 (11%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSN------SRVAQTLDDVPDGPPINIEMFILNTTT 747 + +LR+ +YEF +I K G+PS ++ T +PD P E+ + TT Sbjct: 6934 VPNLRQGAEYEFRVIAENKAGLGRPSQVTHPFTAKPPYTTPGIPDQP----EVEDVTATT 6989 Query: 748 VHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYS 807 + + WSPP ITGY + A V I +TV T+ L Y Sbjct: 6990 ITISWSPPSYD-GGSKITGYTIESK---SDATMRWVKIESTVPD-TTYTAARLKELSEYQ 7044 Query: 808 VQIAAETIIGLGPFSQ 823 ++AA G G FS+ Sbjct: 7045 FRVAAINKAGRGDFSK 7060 Score = 40.7 bits (91), Expect = 0.24 Identities = 31/99 (31%), Positives = 43/99 (43%), Gaps = 9/99 (9%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 P P P NV D S+TLSW + G + I Y +E+ +ET R +R Sbjct: 8963 PPAPGVPKASNVRDDSITLSWQPPHSDGGAEIHNYILEI--KET-------RGTRWLRAT 9013 Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602 +++ ++ V L G Y F V EN GL S S Sbjct: 9014 RKQLKSPNFRVTGLSKGREYEFRVAAENEAGLGAFSKTS 9052 Score = 40.3 bits (90), Expect = 0.31 Identities = 30/103 (29%), Positives = 43/103 (41%), Gaps = 11/103 (10%) Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563 PGPP P +V TS+ L+WS + G S + GY L + RN W + Sbjct: 2723 PGPPPPPTPTHVDRTSIHLTWSPPDDDGGSEVTGY--------ILEKRDKARNK--WTKV 2772 Query: 564 ARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605 + + + + V L Y F V N G PS SD++ Sbjct: 2773 NKEPIPEISFTVTGLTEDAIYDFRVSAVNKAGEGPPSLPSDTL 2815 Score = 40.3 bits (90), Expect = 0.31 Identities = 40/144 (27%), Positives = 61/144 (42%), Gaps = 9/144 (6%) Query: 682 TILHSNDVSG--FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIE 739 T + S+ V G F + L EF + K + KPS V L P G P E Sbjct: 3751 TPVSSDSVDGTTFTVKGLPDDEDVEFRISAVNKAGQSKPSQVTV---LTAKPPGAPGRPE 3807 Query: 740 MFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTN 799 + +N T+ + W P ITGY +V + ++ V +N A ++ +T+ Sbjct: 3808 VSDINKTSATVTWKPSSSD-GGSTITGY--IVEKREKGRDR-WVPVNRKPINAVTMKVTD 3863 Query: 800 LTSGVSYSVQIAAETIIGLGPFSQ 823 LT Y ++ AE IG G S+ Sbjct: 3864 LTEKTDYEFRVIAENRIGQGQPSE 3887 Score = 40.3 bits (90), Expect = 0.31 Identities = 27/78 (34%), Positives = 41/78 (52%), Gaps = 4/78 (5%) Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSR--VAQTLDDVPDGPPINIEMFILNTTTVH 749 F++T L+ T+Y F +I K+ + +PS VA+ D+P P E+ L+ T+V Sbjct: 3960 FKVTGLKDKTEYTFRIIAENKEGQSEPSKETVVVAKYGFDIPQEPSAP-EVKRLSPTSVE 4018 Query: 750 LKWSPPELQLQNGIITGY 767 L W+PP ITGY Sbjct: 4019 LSWTPPRSD-GGADITGY 4035 Score = 39.9 bits (89), Expect = 0.41 Identities = 30/104 (28%), Positives = 41/104 (39%), Gaps = 8/104 (7%) Query: 496 RAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPR 555 RA +PGPP P +V +TL+W+ G + ILGY VE + + Sbjct: 2613 RAKPPYDVPGPPGIPDISDVDKNRMTLTWTPPTDDGGAKILGYIVEKCDADRKRWTKAHK 2672 Query: 556 NSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599 V + V L G YMF V EN+ G+ S Sbjct: 2673 ED--------LVTELTLTVYDLTEGTNYMFRVSAENAAGVGESS 2708 Score = 39.9 bits (89), Expect = 0.41 Identities = 31/104 (29%), Positives = 44/104 (42%), Gaps = 11/104 (10%) Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562 +P P +P ++ +T+ WS G S I GY VE+ P +SR W Sbjct: 5177 VPDKPDQPDVTDIDKNEMTVKWSSPYSDGGSKITGYIVEM---------KEPYSSR-WSQ 5226 Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVT 606 + + T + V L G Y F + EN G S PS S + T Sbjct: 5227 VTKTTDFT-FKVTRLTEGKDYQFRIIAENKAGQSQPSEPSRTFT 5269 Score = 39.9 bits (89), Expect = 0.41 Identities = 60/250 (24%), Positives = 92/250 (36%), Gaps = 26/250 (10%) Query: 226 GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVS--- 282 GG + + R G M + R V+ D S ++N++ E + A N+ G S Sbjct: 9477 GGSEITHYIVERRLKGSYMWIDRT-VVHDTSCSVNNLVEDKEYTFRVTAVNAAGNESDPS 9535 Query: 283 -ASGYLTVYDP-----PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF 336 AS PSI + + V G F C +G P+P + W G + Sbjct: 9536 RASESFVAESQLPGAAPSILIEIQNAMVAEGQTGMFMCKISGSPKPKVSWMHHGRE--LM 9593 Query: 337 PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP 396 PG + VF ++ + TD TI+ A N GS +L + RP Sbjct: 9594 PGRKHNITEDNGVF---KIVVFSVTDYETGMYTII--AKNKHGSVRSSAELLI----QRP 9644 Query: 397 PPI-ITNGPSNQTLPIKSMAVFPCT-AICTPEPIIAW-YFEGEALIQNHRRNVTNDGTLV 453 P + I + ++ P T TP+P W +GE L R + G Sbjct: 9645 PQLSIDRHLQDLSVRAGQEIHIPVTLTYGTPKPTFTWRRHDGEELDTRGRYSTKEQGR-- 9702 Query: 454 LKDLDKSDSG 463 + D + D G Sbjct: 9703 VHDFELPDLG 9712 Score = 39.1 bits (87), Expect = 0.72 Identities = 41/137 (29%), Positives = 62/137 (45%), Gaps = 12/137 (8%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSR---VAQTLDDVPDGPPINIEMFILNTTTVHL 750 IT L + +YEF +I K G+PS+ VA+ +VP PP +++ L +V L Sbjct: 4843 ITDLVEKNEYEFRVIAENKVGPGEPSSPSERIVAKAPYEVP-SPPKSLKATDLTPISVTL 4901 Query: 751 KWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT--SLIMTNLTSGVSYSV 808 WS P L NG G +V +++ S N + H T SL + NL Y Sbjct: 4902 NWSAP---LSNG---GSPIVGYTIEMKDKFSTRWTNVSEHMVTTLSLNVPNLKEKNDYQF 4955 Query: 809 QIAAETIIGLGPFSQKV 825 ++ A G G S+ + Sbjct: 4956 RVIAHNKAGPGQPSEPI 4972 Score = 38.7 bits (86), Expect = 0.96 Identities = 42/187 (22%), Positives = 78/187 (41%), Gaps = 20/187 (10%) Query: 97 RNATLHVAVLREEFRLEPESKQSAQGD-TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155 + T + V EF + +A+ D T+VLEC + W K+ +L Sbjct: 1071 KTQTADLKVQAAEFVKPLNNTSAAEYDETIVLEC--ELSNELVPCQWYKDD--VLITVGP 1126 Query: 156 RMHLVDGGN---LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVV 212 ++ ++D G LV+ D R D G ++C+ G +ES+ ATL + + E Sbjct: 1127 KVEVIDDGKKRKLVLHDVRPEDTGNFRCV----VGDKESS-ATLDVKASEIMKPLAEVTA 1181 Query: 213 AQTGSSVTFQCRVGGDPLPDVLWRRSA---GGGNMPLGRVKVLDDGSLR---LDNVILAD 266 + + +C V P + W + + + +V+ DG R + +V+ D Sbjct: 1182 PEFAETAVLECEV-SHPKAEATWLKDGQPITPEELTSKKYEVVSDGRKRRLIIHDVVKDD 1240 Query: 267 EGEYSCE 273 E++C+ Sbjct: 1241 NAEFTCK 1247 Score = 38.7 bits (86), Expect = 0.96 Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 3/55 (5%) Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEV---FSRETLSGNNTP 554 +PG P+ P+ ++T+TSV L WS + G + I Y VE FS TP Sbjct: 2823 VPGAPSTPVPSDITETSVHLEWSPPSNNGGAEITEYIVEQKDRFSSRWTKAGETP 2877 Score = 38.7 bits (86), Expect = 0.96 Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 6/127 (4%) Query: 693 EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGP--PINIEMFILNTTTVHL 750 ++ L + +YEF +I K G+PSN T D P P ++ + T+ L Sbjct: 3180 KVNDLTEKNQYEFRVIAENKVGPGEPSNPSARFTAKAPFDEPEAPYSLAASDITPTSATL 3239 Query: 751 KWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQI 810 W PP+ + I+ GY + D +++ +N + Q TS +TNL Y ++ Sbjct: 3240 SWLPPDSDGGSPIL-GYTLETK--DRFSSR-WTKVNKGLLQETSFKVTNLEENNEYVYRV 3295 Query: 811 AAETIIG 817 AE G Sbjct: 3296 IAENKAG 3302 Score = 38.3 bits (85), Expect = 1.3 Identities = 36/139 (25%), Positives = 62/139 (44%), Gaps = 9/139 (6%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEG---KPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHL 750 +T L + ++Y+F +I G +PS+ + A+ D P P E+ + T + L Sbjct: 2380 VTGLTEGSEYQFRVIAENPAGPGPASEPSDLQKAKLPFDAPSAPG-KPEVTSADKTQMEL 2438 Query: 751 KWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQI 810 W+ P+ ITGY + K ++ TT + T+ I + L Y ++ Sbjct: 2439 TWAVPDSD-GGSPITGYIIQKK---ENTGKWTQSLKTTTTETTATIKS-LIEKKEYEFRV 2493 Query: 811 AAETIIGLGPFSQKVYFNI 829 AA + G GPFS+ + I Sbjct: 2494 AAVNLAGTGPFSEPSDYQI 2512 Score = 38.3 bits (85), Expect = 1.3 Identities = 36/131 (27%), Positives = 56/131 (42%), Gaps = 8/131 (6%) Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPS---NSRVAQTLDDVPDGPPINIEMFILNTTTV 748 F +T L + Y+F + K EG PS ++ A+ DVP P + I T+ V Sbjct: 2782 FTVTGLTEDAIYDFRVSAVNKAGEGPPSLPSDTLKAKLPFDVPGAPSTPVPSDITETS-V 2840 Query: 749 HLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSV 808 HL+WSPP NG +V D +++ A T ++ + +L G Y Sbjct: 2841 HLEWSPPS---NNGGAEITEYIVEQKDRFSSRWTKA-GETPGDTVTITLKDLKEGNEYQF 2896 Query: 809 QIAAETIIGLG 819 ++ A G G Sbjct: 2897 RVIAVNPAGPG 2907 Score = 38.3 bits (85), Expect = 1.3 Identities = 32/102 (31%), Positives = 46/102 (45%), Gaps = 11/102 (10%) Query: 502 SLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV 561 ++P P P NV TS+T++W+++ G S I GY +E + +G WV Sbjct: 6269 TVPSAPGAPDVSNVKATSMTVTWTKSISDGGSPITGYVLE--KCDVSTGR--------WV 6318 Query: 562 VIAR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602 + R + +T VV L Y F V N G S PS S Sbjct: 6319 PVNRVPLRETSLVVDQLREKSEYCFRVVAHNVAGESKPSEPS 6360 Score = 38.3 bits (85), Expect = 1.3 Identities = 30/115 (26%), Positives = 49/115 (42%), Gaps = 8/115 (6%) Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---SLRLDNVILA 265 E ++A+ G S + G P P V W G P +++ ++ + NV A Sbjct: 8179 EPIMAKVGESFRIEVPYTGIPTPAVTWSFD-GRPLKPSAHIRIDTSNRASTITVKNVEKA 8237 Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320 + G Y+ +N+ GA S + V+D P P +E NV+ T T + P Sbjct: 8238 NGGRYTINLKNTAGAESLDVEVRVFDRPGPPRGP----LEMSNVSESTVTLSWSP 8288 Score = 37.1 bits (82), Expect = 2.9 Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 4/88 (4%) Query: 733 GPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQA 792 GPP ++ T++HL WSPP+ +TGY ++ D NK +N Sbjct: 2724 GPPPPPTPTHVDRTSIHLTWSPPD-DDGGSEVTGY--ILEKRDKARNK-WTKVNKEPIPE 2779 Query: 793 TSLIMTNLTSGVSYSVQIAAETIIGLGP 820 S +T LT Y +++A G GP Sbjct: 2780 ISFTVTGLTEDAIYDFRVSAVNKAGEGP 2807 Score = 36.7 bits (81), Expect = 3.9 Identities = 30/100 (30%), Positives = 43/100 (43%), Gaps = 10/100 (10%) Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562 +P P+ P ++ TS+ L W+ G S I GY +E ++ SG TP V Sbjct: 3704 VPQAPSAPEVRRLSPTSIQLDWTPPFADGGSDITGYIIE---KKEKSGRWTP-------V 3753 Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602 + V T + VK L F + N G S PS V+ Sbjct: 3754 SSDSVDGTTFTVKGLPDDEDVEFRISAVNKAGQSKPSQVT 3793 Score = 36.3 bits (80), Expect = 5.1 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 4/83 (4%) Query: 404 PSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDK 459 P T+ I+ A F C EP+I W+ + LI + + + D TL+++D + Sbjct: 10652 PLENTMAIEGNAGRFECEVSALSEPLITWFRGKKELIISIKYKMLYDDHKYTLIVQDSEF 10711 Query: 460 SDSGTYTCVASSRHGKYVWSGAL 482 D YTC A + +G S +L Sbjct: 10712 DDIDEYTCKAVNSYGHATSSASL 10734 Score = 35.9 bits (79), Expect = 6.7 Identities = 35/133 (26%), Positives = 59/133 (44%), Gaps = 8/133 (6%) Query: 688 DVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSR---VAQTLDDVPDGPPINIEMFILN 744 D + L++ +Y+F +I G PS++ VA+ DVPD P L+ Sbjct: 2879 DTVTITLKDLKEGNEYQFRVIAVNPAGPGSPSDACKPFVAKPPYDVPDAPGKPAPSD-LS 2937 Query: 745 TTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGV 804 T+V L W+PP ITGY V + D + + A + + T++++ +L Sbjct: 2938 PTSVTLTWTPPPSD-GGSPITGYTVEMK--DKFSTRWTKATRELISE-TTVVLPDLKEKE 2993 Query: 805 SYSVQIAAETIIG 817 Y ++ AE G Sbjct: 2994 EYQFRVIAENKAG 3006 Score = 35.9 bits (79), Expect = 6.7 Identities = 30/124 (24%), Positives = 57/124 (45%), Gaps = 8/124 (6%) Query: 693 EITSLRKYTKYEFFLIPFYKKFEGKPSNSR---VAQTLDDVPDGPPINIEMFILNTTTVH 749 ++T L + T YEF +I + +G+PS +A++ DVP P + + T++ Sbjct: 3860 KVTDLTEKTDYEFRVIAENRIGQGQPSEPSAKFIAKSPFDVPTAPGAP-KASDITPTSLT 3918 Query: 750 LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQ 809 L W+PP +G N ++ W D + + + + + + +T L Y+ + Sbjct: 3919 LTWTPP---TDDGGSPITNFIIEWKDKFSTRFTI-LKKDLFVELTFKVTGLKDKTEYTFR 3974 Query: 810 IAAE 813 I AE Sbjct: 3975 IIAE 3978 Score = 35.9 bits (79), Expect = 6.7 Identities = 22/74 (29%), Positives = 29/74 (39%), Gaps = 1/74 (1%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI-LPAGGLFFLRATHGRVHS 78 D+ + A L+C+ G P P IRW+K + H SI Sbjct: 10897 DIFIVEGSAARLDCKVTGVPEPNIRWFKDHKEIFDGQHYSIEFGEDDETCSLIIQEAFLQ 10956 Query: 79 DAGVYWCEATNSYG 92 DAG Y C A+N G Sbjct: 10957 DAGTYTCLASNLLG 10970 >UniRef50_Q9BMN8 Cluster: Tyrosine-protein phosphatase Lar-like precursor; n=6; Caenorhabditis|Rep: Tyrosine-protein phosphatase Lar-like precursor - Caenorhabditis elegans Length = 2200 Score = 102 bits (244), Expect = 7e-20 Identities = 86/309 (27%), Positives = 129/309 (41%), Gaps = 20/309 (6%) Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP-AGGLFFLRAT 72 ++ +P TV + CRA G+P P++ W G + SI A GL LR Sbjct: 50 LVVRPDSSTVVDESKISFFCRADGNPLPSVIWRVNGKSITDHNRISIKSLATGLSTLRFE 109 Query: 73 HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE------EFRLEPESKQSAQGDTVV 126 + +A V C A N A+L V + + L P K QG T Sbjct: 110 RVSLDDNATVVSCSADNGVANPVVAEASLTVVPRDKVPIGFPQIELHPSLKSVEQGKTAY 169 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIAR 183 + C RG P V W ++ L D R + GN L+IQ AR+ D G+Y+CIAR Sbjct: 170 VSCRV-RGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGALMIQHAREEDQGKYECIAR 228 Query: 184 NAAGTRESAIATLKIHIK---PYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239 N G S A L + ++ PY E V G ++ C G P+P V W+++ Sbjct: 229 NTLGVAHSKAANLYVKVRRVPPYFSYKLERQYVVGVGGNINLTCVAVGYPMPRVFWKKT- 287 Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PPSINL 297 M L G L + ++C A +++G + A+ + + PP +N+ Sbjct: 288 --DLMVLDDPSTAPIGKNVLTLTHVESTENFTCVAVSALGNIEATTTVIAKELPPPPVNI 345 Query: 298 SPNSVNVES 306 +SV ES Sbjct: 346 VVSSVTSES 354 Score = 64.9 bits (151), Expect = 1e-08 Identities = 77/286 (26%), Positives = 119/286 (41%), Gaps = 35/286 (12%) Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT---DAGRYQCIARNAAGTRE 190 G+P P+V W+ NG+++ + + G ++ R + +A C A N Sbjct: 73 GNPLPSVIWRVNGKSITDHNRISIKSLATGLSTLRFERVSLDDNATVVSCSADNGVANPV 132 Query: 191 SAIATL------KIHIK-PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 A A+L K+ I P + P + G + CRV GDP VLW R + Sbjct: 133 VAEASLTVVPRDKVPIGFPQIELHPSLKSVEQGKTAYVSCRVRGDPRAKVLWLRDLIPLD 192 Query: 244 MPL-GRVKVL---DDGSLRLDNVILADEGEYSCEAENSVGAV---SASGYLTVYDPP--- 293 + GR V + G+L + + D+G+Y C A N++G +A+ Y+ V P Sbjct: 193 IRADGRYSVSTIGNPGALMIQHAREEDQGKYECIARNTLGVAHSKAANLYVKVRRVPPYF 252 Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353 S L V GN+ TC A G P P +FW + P +TA G Sbjct: 253 SYKLERQYVVGVGGNI-NLTCVAVGYPMPRVFWKKTDLMVLDDP--------STAPI-GK 302 Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPI 399 VLT+ +S C AV+ G+ + TV + + PPP+ Sbjct: 303 NVLTLTHV---ESTENFTCVAVSALGN--IEATTTVIAKELPPPPV 343 Score = 61.7 bits (143), Expect = 1e-07 Identities = 64/276 (23%), Positives = 110/276 (39%), Gaps = 15/276 (5%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGLFFL 69 P I P +V + + A ++CR G P + W + + + +D S+ G L Sbjct: 151 PQIELHPSLKSVEQGKTAYVSCRVRGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGAL 210 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE----EFRLEPESKQSAQGDTV 125 H R D G Y C A N+ G A S+ A L+V V R ++LE + G + Sbjct: 211 MIQHAR-EEDQGKYECIARNTLGVAHSKAANLYVKVRRVPPYFSYKLERQYVVGV-GGNI 268 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 L C+ G P P V+WKK +L D + + L + T+ + C+A +A Sbjct: 269 NLTCVAV-GYPMPRVFWKKTDLMVLDDPSTAP--IGKNVLTLTHVESTE--NFTCVAVSA 323 Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD--VLWRRSAGGGN 243 G E+ + + P + V +T++ + + V +R G Sbjct: 324 LGNIEATTTVIAKELPPPPVNIVVSSVTSESVVITWKPPKYNEAINKYVVNYRLKYSEGR 383 Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279 G+ + SL +D ++ E++ + VG Sbjct: 384 SSRGKTMETLENSLVIDGLVAFQTYEFTVRSAGPVG 419 Score = 52.8 bits (121), Expect = 5e-05 Identities = 47/192 (24%), Positives = 76/192 (39%), Gaps = 13/192 (6%) Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350 DP + + P+S V + F C A G P P++ W V G ++ ++ Sbjct: 46 DPARLVVRPDSSTVVDESKISFFCRADGNPLPSVIWRVNGKSI-----TDHNRISIKSLA 100 Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV-RGKLTVTSDDDRPP--PIITNGPSNQ 407 G++ L +D+ + CSA N + V LTV D P P I PS + Sbjct: 101 TGLSTLRFERVSLDDNATVVSCSADNGVANPVVAEASLTVVPRDKVPIGFPQIELHPSLK 160 Query: 408 TLPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRR----NVTNDGTLVLKDLDKSDS 462 ++ A C P + W + L I+ R + N G L+++ + D Sbjct: 161 SVEQGKTAYVSCRVRGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGALMIQHAREEDQ 220 Query: 463 GTYTCVASSRHG 474 G Y C+A + G Sbjct: 221 GKYECIARNTLG 232 Score = 51.6 bits (118), Expect = 1e-04 Identities = 80/352 (22%), Positives = 138/352 (39%), Gaps = 39/352 (11%) Query: 485 DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFS 544 DSP++ + A +PG P + + L+W + + SS ++GY V + Sbjct: 521 DSPLSTLV---TVATRQGIPGQPPMLTVKALDSRRMQLTWDK--PLYSSPVVGYTVRYNT 575 Query: 545 RETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPG-----ITYMFIVRTENSHGLSGPS 599 + VV + +Y + T I +T S LS P+ Sbjct: 576 SDGEKELTLTSPHEKHVVTGLHPDKYYYFRVAAYSDRGQGEFTEPMISKTIASIPLSSPT 635 Query: 600 PVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFY 659 VS + T W+G + N +LT + + DSKT L E + Sbjct: 636 IVSAAATSSKSVEIRWKGP----EQKKLNGVLTAYRINYFRLE--DSKTANL--ESVE-- 685 Query: 660 YLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPS 719 Y +D+ + + +++ +D + + ++ L Y+ YE + G S Sbjct: 686 -------YDEDMDDSSSFLDRMSVVVPSDATSYVLSDLLPYSSYEITVAASTMDGYGPES 738 Query: 720 NSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNV----VVNW-- 773 + RV +TL+DVP P N + + T+V L W P NG + GY V +VN Sbjct: 739 SIRVVKTLEDVPSAPR-NFNAELTSATSVKLTWDAP--AAANGALLGYYVYLDRMVNGEP 795 Query: 774 -LDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQK 824 ++ + K +V I + + L +L YS ++ A G G FS++ Sbjct: 796 VVEKGSKKRIVMIRDSSKRYFEL--DSLDPNTEYSFRLNAFNRNGDGEFSER 845 Score = 51.2 bits (117), Expect = 2e-04 Identities = 32/117 (27%), Positives = 58/117 (49%), Gaps = 6/117 (5%) Query: 715 EGKPSNS-RVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNW 773 EG+ N+ T PDG PI+++ ++ V + W PP + +NG IT Y +++ Sbjct: 940 EGRSQNATETIATPVGSPDGEPIDVQYEVMKGKIV-VSWRPPSEEKRNGNITSYKAILSA 998 Query: 774 LDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNID 830 +D A++ + +S N+ +Y ++AA T+ G+GP+S + N D Sbjct: 999 MDATADRYEQPV--PAPSTSSTFEVNVRR--AYLFKVAAATMKGIGPYSPVLTINPD 1051 Score = 37.1 bits (82), Expect = 2.9 Identities = 34/124 (27%), Positives = 52/124 (41%), Gaps = 4/124 (3%) Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTV--H 749 FE+ SL T+Y F L F + +G+ S + T P+ P I + V Sbjct: 816 FELDSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQGIPPEAPEIVSVSLDRDEPPVVAR 875 Query: 750 LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQ 809 ++W P+++ I YN+ + P S V T S ++ L GV Y V Sbjct: 876 IEWKMPKMKPNETPIEKYNLWLRAQGYP--DSYVKAKTVDGTDLSTTISGLWMGVVYDVL 933 Query: 810 IAAE 813 +AAE Sbjct: 934 LAAE 937 >UniRef50_A7RK32 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1103 Score = 100 bits (240), Expect = 2e-19 Identities = 76/300 (25%), Positives = 123/300 (41%), Gaps = 25/300 (8%) Query: 109 EFRLEPESKQSAQGDTVVLEC---LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNL 165 + + P S+++ +GD V L C + R S + W+ + + + D ++ Sbjct: 537 QISVHPPSQKAMRGDNVTLRCRVQVVQRNSSSVRLQWRLGYEVISERDITDFVRTDDDDI 596 Query: 166 VIQDARQ-------TDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSS 218 V ++ +DAG YQCIA N G++ S A L++ P L P DV G Sbjct: 597 VTYNSDLFLISVDFSDAGLYQCIASNKYGSQFSKKARLEVLEFPVLTRKPHDVSVHVGGL 656 Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD----DGSLRLDNVILADEGEYSCEA 274 + C G P+P + WR G P K ++ + + N D G Y+C A Sbjct: 657 IKLPCAATGYPVPVISWRMGDGKSKFPAAEEKRIEHLPSEHLFIIRNARGVDTGAYTCTA 716 Query: 275 ENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334 N G+++A+ Y+TV + P S S V +G A C A+G P P W + + Sbjct: 717 TNGAGSINATAYVTVLEVPRFMQSMVSKRVRTGESAVLECKASGSPMPRFTWYKDDKKVT 776 Query: 335 IFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394 + A V G ++ + T D T C N G++ +LTV + Sbjct: 777 L---------SARVVAHGQLLVFV--TVLRDDEGTYTCQVSNSLGTARQNTRLTVVEGSE 825 Score = 88.6 bits (210), Expect = 9e-16 Identities = 83/300 (27%), Positives = 122/300 (40%), Gaps = 23/300 (7%) Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAG----GSPSPAIRWYKGGVLV----VSDTHR 58 TS P I P R TL CR S S ++W G ++ ++D R Sbjct: 531 TSNPIPQISVHPPSQKAMRGDNVTLRCRVQVVQRNSSSVRLQWRLGYEVISERDITDFVR 590 Query: 59 S----ILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP 114 + I+ FL + SDAG+Y C A+N YG+ S+ A L V R +P Sbjct: 591 TDDDDIVTYNSDLFLISVD---FSDAGLYQCIASNKYGSQFSKKARLEVLEFPVLTR-KP 646 Query: 115 ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDG--DSRM-HLVDGGNLVIQDAR 171 G + L C G P P + W+ F + R+ HL +I++AR Sbjct: 647 HDVSVHVGGLIKLPC-AATGYPVPVISWRMGDGKSKFPAAEEKRIEHLPSEHLFIIRNAR 705 Query: 172 QTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231 D G Y C A N AG+ +A A + + P + +TG S +C+ G P+P Sbjct: 706 GVDTGAYTCTATNGAGS-INATAYVTVLEVPRFMQSMVSKRVRTGESAVLECKASGSPMP 764 Query: 232 DVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291 W + + L V L V+ DEG Y+C+ NS+G + LTV + Sbjct: 765 RFTWYKD--DKKVTLSARVVAHGQLLVFVTVLRDDEGTYTCQVSNSLGTARQNTRLTVVE 822 Score = 68.9 bits (161), Expect = 8e-10 Identities = 59/222 (26%), Positives = 90/222 (40%), Gaps = 12/222 (5%) Query: 254 DGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSVNVESGNVARF 312 + L L +V +D G Y C A N G+ S L V + P + P+ V+V G + + Sbjct: 600 NSDLFLISVDFSDAGLYQCIASNKYGSQFSKKARLEVLEFPVLTRKPHDVSVHVGGLIKL 659 Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372 C ATG P P + W + G+ FP + + I + D+ C Sbjct: 660 PCAATGYPVPVISWRM-GDGKSKFPAAEEKRIEH---LPSEHLFIIRNARGVDT-GAYTC 714 Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432 +A N AGS +TV P ++ + AV C A +P P WY Sbjct: 715 TATNGAGSINATAYVTVLE-----VPRFMQSMVSKRVRTGESAVLECKASGSPMPRFTWY 769 Query: 433 FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474 + + + + R V + LV + + D GTYTC S+ G Sbjct: 770 KDDKKVTLS-ARVVAHGQLLVFVTVLRDDEGTYTCQVSNSLG 810 Score = 52.4 bits (120), Expect = 7e-05 Identities = 35/99 (35%), Positives = 47/99 (47%), Gaps = 6/99 (6%) Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64 YVT E P ++ + V + A L C+A GSP P WYK V T + + A Sbjct: 728 YVTVLEVPRFMQSMVSKRVRTGESAVLECKASGSPMPRFTWYKDDKKV---TLSARVVAH 784 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103 G + T + D G Y C+ +NS GTAR +N L V Sbjct: 785 GQLLVFVT--VLRDDEGTYTCQVSNSLGTAR-QNTRLTV 820 >UniRef50_Q8IZJ1 Cluster: Netrin receptor UNC5B precursor; n=38; Euteleostomi|Rep: Netrin receptor UNC5B precursor - Homo sapiens (Human) Length = 945 Score = 100 bits (240), Expect = 2e-19 Identities = 63/200 (31%), Positives = 98/200 (49%), Gaps = 13/200 (6%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTH---RSILPAGGLFF 68 PY +++P D + +++P L CRA P+ I + G V + H + A GL Sbjct: 48 PYFLQEPQDAYIVKNKPVELRCRA--FPATQIYFKCNGEWVSQNDHVTQEGLDEATGLRV 105 Query: 69 ----LRATHGRVHSDAGV--YWCE--ATNSYGTARSRNATLHVAVLREEFRLEPESKQSA 120 + + +V G+ YWC+ A +S GT +SR A + +A LR+ F EP K+ Sbjct: 106 REVQIEVSRQQVEELFGLEDYWCQCVAWSSAGTTKSRRAYVRIAYLRKNFDQEPLGKEVP 165 Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180 V+L+C PP G P V W KN + D+ L NL+I+ AR +D Y C Sbjct: 166 LDHEVLLQCRPPEGVPVAEVEWLKNEDVIDPTQDTNFLLTIDHNLIIRQARLSDTANYTC 225 Query: 181 IARNAAGTRESAIATLKIHI 200 +A+N R S AT+ +++ Sbjct: 226 VAKNIVAKRRSTTATVIVYV 245 >UniRef50_Q6UWL6 Cluster: Kin of IRRE-like protein 2 precursor; n=19; Theria|Rep: Kin of IRRE-like protein 2 precursor - Homo sapiens (Human) Length = 708 Score = 100 bits (240), Expect = 2e-19 Identities = 107/396 (27%), Positives = 159/396 (40%), Gaps = 37/396 (9%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGS--PSPAIRWYKGGVLVVSDT-HRSILPAGGL 66 EAP ++ P V++ PA L CR+ G P+P + W++ GVL+ T H+++L G Sbjct: 124 EAPQVLGGP-SVSLVAGVPANLTCRSRGDARPTPELLWFRDGVLLDGATFHQTLLKEGTP 182 Query: 67 FFLRATHGRV---HSDAGVYWCEA-TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122 + +T H D + C A + + T R TL + E L +G Sbjct: 183 GSVESTLTLTPFSHDDGATFVCRARSQALPTGRDTAITLSLQY-PPEVTLSASPHTVQEG 241 Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182 + V+ C P W K G +L R+ +V + + + C Sbjct: 242 EKVIFLCQATAQPPVTGYRWAKGGSPVLGARGPRLEVVADASFLTEPV--------SCEV 293 Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242 NA G+ + A L + P L PE V G +F C G+PLP V W R GG Sbjct: 294 SNAVGSANRSTA-LDVLFGPILQAKPEPVSVDVGEDASFSCAWRGNPLPRVTWTRR--GG 350 Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV---SASGYLTVYDPPSINLSP 299 LG +LRL +V D G+Y C AE + + +A LTV PP + + Sbjct: 351 AQVLG-----SGATLRLPSVGPEDAGDYVCRAEAGLSGLRGGAAEARLTVNAPPVVT-AL 404 Query: 300 NSVNVESGNVARFTCTATGRPEP-TMFWS-VEGNRTIIFPG-MSRDKYHATAVFDG---- 352 +S AR C P P + WS EG G + + A G Sbjct: 405 HSAPAFLRGPARLQCLVFASPAPDAVVWSWDEGFLEAGSQGRFLVETFPAPESRGGLGPG 464 Query: 353 -VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387 ++VL I+ T ++D + CSA N G + L Sbjct: 465 LISVLHISGTQESDFSRSFNCSARNRLGEGGAQASL 500 Score = 89.0 bits (211), Expect = 7e-16 Identities = 121/455 (26%), Positives = 187/455 (41%), Gaps = 67/455 (14%) Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67 +G +P+ ++QP D+ V + A L C A G+ ++W K G+ + LP + Sbjct: 20 AGPSPHFLQQPEDLVVLLGEEARLPC-ALGAYWGLVQWTKSGLALGGQRD---LPGWSRY 75 Query: 68 FL--RATHGR--VH------SDAGVYWCEATNSYGTARSRNATLHVAVLREEFR-LEPES 116 ++ A +G+ +H D Y C+AT + RSR A LHV V E + L S Sbjct: 76 WISGNAANGQHDLHIRPVELEDEASYECQATQA--GLRSRPAQLHVLVPPEAPQVLGGPS 133 Query: 117 KQSAQGDTVVLECLPPRGS--PEPNVYWKKNGQTLLFDGDS--RMHLVDG------GNLV 166 G L C RG P P + W ++G +L DG + + L +G L Sbjct: 134 VSLVAGVPANLTCRS-RGDARPTPELLWFRDG--VLLDGATFHQTLLKEGTPGSVESTLT 190 Query: 167 IQDARQTDAGRYQCIARNAA--GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR 224 + D + C AR+ A R++AI TL + P + Q G V F C+ Sbjct: 191 LTPFSHDDGATFVCRARSQALPTGRDTAI-TLSLQYPPEVTLSASPHTVQEGEKVIFLCQ 249 Query: 225 VGGDPLPDVLWRRSAGGGNMPLG----RVKVLDDGSLRLDNVILADEGEYSCEAENSVGA 280 P V R A GG+ LG R++V+ D S + V SCE N+VG+ Sbjct: 250 ATAQP--PVTGYRWAKGGSPVLGARGPRLEVVADASFLTEPV--------SCEVSNAVGS 299 Query: 281 VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340 + S L V P + P V+V+ G A F+C G P P + W+ G ++ G + Sbjct: 300 ANRSTALDVLFGPILQAKPEPVSVDVGEDASFSCAWRGNPLPRVTWTRRGGAQVLGSGAT 359 Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII 400 + + ++ D D VC A AG S +RG PP++ Sbjct: 360 ------------LRLPSVGPEDAGD----YVCRA--EAGLSGLRGGAAEARLTVNAPPVV 401 Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEP-IIAWYFE 434 T S ++ A C +P P + W ++ Sbjct: 402 TALHSAPAF-LRGPARLQCLVFASPAPDAVVWSWD 435 >UniRef50_UPI0000F20186 Cluster: PREDICTED: similar to cell adhesion molecule NCAM; n=7; Danio rerio|Rep: PREDICTED: similar to cell adhesion molecule NCAM - Danio rerio Length = 1157 Score = 100 bits (239), Expect = 3e-19 Identities = 75/288 (26%), Positives = 125/288 (43%), Gaps = 10/288 (3%) Query: 43 IRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLH 102 I W K G V +D H L + ++ SD G Y CE +S G ++ N+ ++ Sbjct: 528 INWLKDGEDVDTDRHVVEKNDESSSTLNLKNVQL-SDTGRYTCEFEDSNGNKKTTNSQIY 586 Query: 103 VAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG 162 V +F + T ++ C+ G PE ++W +N + + DG S + ++ Sbjct: 587 V-YKTPDFGQTRTFHEFLVNQTAIIPCMVT-GKPEVEIHWFRNDRMIHDDGRSHLKILPD 644 Query: 163 GNLVIQDARQTDAGRYQCIARNAAG--TRESAIATLKIHIKPYLITGPE--DVVAQTGSS 218 L+I + D G Y C + TR I+ + ++ P ++ E V A +S Sbjct: 645 RTLMIVGIQHEDRGTYICEGKIKGRPITRNLPISVV-VNEPPTVLIHEEKKSVFAGPNTS 703 Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSV 278 ++ C V G P+P + W + + D L + V +D GEY C A N + Sbjct: 704 LSIACLVKGAPVPTITWTTPSSFNDYRYSYNT--DKSELTISAVTRSDYGEYICTASNKI 761 Query: 279 GAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326 G SA L V + P++ + N +++ G A C ATG P P + W Sbjct: 762 GESSAIFVLDVSELPTVVFTENKLSIIPGESASVFCNATGHPAPAVQW 809 Score = 86.2 bits (204), Expect = 5e-15 Identities = 77/283 (27%), Positives = 114/283 (40%), Gaps = 24/283 (8%) Query: 26 HQPATLNCRAGGSPSPAIRWYKGGVLVVSD--THRSILPAGGLFFLRATHGRVHSDAGVY 83 +Q A + C G P I W++ ++ D +H ILP L + G H D G Y Sbjct: 605 NQTAIIPCMVTGKPEVEIHWFRNDRMIHDDGRSHLKILPDRTLMIV----GIQHEDRGTY 660 Query: 84 WCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA---QGDTVVLECLPPRGSPEPNV 140 CE G +RN + V V L E K+S ++ + CL +G+P P + Sbjct: 661 ICEGKIK-GRPITRNLPISVVVNEPPTVLIHEEKKSVFAGPNTSLSIACLV-KGAPVPTI 718 Query: 141 YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200 W F+ + D L I ++D G Y C A N G SAI L + Sbjct: 719 TWTTPSS---FNDYRYSYNTDKSELTISAVTRSDYGEYICTASNKIG-ESSAIFVLDVSE 774 Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLD 260 P ++ + G S + C G P P V W R + K+ + L L+ Sbjct: 775 LPTVVFTENKLSIIPGESASVFCNATGHPAPAVQWVRKDT-------QQKMSGEPELILE 827 Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVY--DPPSINLSPNS 301 N++ +D G YSC A N VG + L + P ++S S Sbjct: 828 NIMPSDGGFYSCIATNIVGTTTGDFQLITWPETPSQFSMSAGS 870 Score = 78.2 bits (184), Expect = 1e-12 Identities = 82/363 (22%), Positives = 164/363 (45%), Gaps = 45/363 (12%) Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-----GGNLVIQDARQTDAG 176 G++++L C + E ++ W K+G+ D D+ H+V+ L +++ + +D G Sbjct: 513 GNSILLLC---KADTEGDINWLKDGE----DVDTDRHVVEKNDESSSTLNLKNVQLSDTG 565 Query: 177 RYQCIARNAAGTRESAIATLKIHIKP---YLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233 RY C ++ G +++ + + ++ P T E +V QT C V G P ++ Sbjct: 566 RYTCEFEDSNGNKKTTNSQIYVYKTPDFGQTRTFHEFLVNQTA---IIPCMVTGKPEVEI 622 Query: 234 LW-RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-- 290 W R + +K+L D +L + + D G Y CE + ++ + ++V Sbjct: 623 HWFRNDRMIHDDGRSHLKILPDRTLMIVGIQHEDRGTYICEGKIKGRPITRNLPISVVVN 682 Query: 291 DPPSINLSPNSVNVESG-NVA-RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348 +PP++ + +V +G N + C G P PT+ W+ + + DK Sbjct: 683 EPPTVLIHEEKKSVFAGPNTSLSIACLVKGAPVPTITWTTPSSFNDYRYSYNTDK----- 737 Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408 + LTI+ ++D +C+A N G S + V + P + T + Sbjct: 738 -----SELTISAVTRSDY-GEYICTASNKIGES---SAIFVLDVSELPTVVFTENKLS-I 787 Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468 +P +S +VF C A P P + W + ++ ++ ++ + L+L+++ SD G Y+C+ Sbjct: 788 IPGESASVF-CNATGHPAPAVQW------VRKDTQQKMSGEPELILENIMPSDGGFYSCI 840 Query: 469 ASS 471 A++ Sbjct: 841 ATN 843 Score = 71.7 bits (168), Expect = 1e-10 Identities = 79/332 (23%), Positives = 131/332 (39%), Gaps = 24/332 (7%) Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS- 256 I K +I G DV Q G+S+ C+ D D+ W + + V+ D+ S Sbjct: 497 IDAKLDIILGDPDV--QVGNSILLLCKA--DTEGDINWLKDGEDVDTDRHVVEKNDESSS 552 Query: 257 -LRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314 L L NV L+D G Y+CE E+S G + + + VY P + A C Sbjct: 553 TLNLKNVQLSDTGRYTCEFEDSNGNKKTTNSQIYVYKTPDFGQTRTFHEFLVNQTAIIPC 612 Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374 TG+PE + W +R I G S K + T++ + +++ R T +C Sbjct: 613 MVTGKPEVEIHW-FRNDRMIHDDGRSHLK-----ILPDRTLMIVGI--QHEDRGTYICEG 664 Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL--PIKSMAVFPCTAICTPEPIIAWY 432 G R L ++ + PP ++ + P S+++ C P P I W Sbjct: 665 -KIKGRPITRN-LPISVVVNEPPTVLIHEEKKSVFAGPNTSLSI-ACLVKGAPVPTITWT 721 Query: 433 FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492 + N T+ L + + +SD G Y C AS++ G+ S ++D P + Sbjct: 722 TPSSFNDYRYSYN-TDKSELTISAVTRSDYGEYICTASNKIGES--SAIFVLDVSELPTV 778 Query: 493 HFFRAADVSSLPGPPTKPITHNVTDTSVTLSW 524 F +S +PG + + + W Sbjct: 779 -VFTENKLSIIPGESASVFCNATGHPAPAVQW 809 Score = 39.1 bits (87), Expect = 0.72 Identities = 47/186 (25%), Positives = 73/186 (39%), Gaps = 20/186 (10%) Query: 6 VTSGEAPYII--EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63 V E P ++ E+ V + ++ C G+P P I W +D S Sbjct: 679 VVVNEPPTVLIHEEKKSVFAGPNTSLSIACLVKGAPVPTITWTTPSSF--NDYRYSYNTD 736 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS-AQG 122 + A SD G Y C A+N G + S L V+ L + E+K S G Sbjct: 737 KSELTISAV---TRSDYGEYICTASNKIGES-SAIFVLDVSELPTV--VFTENKLSIIPG 790 Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182 ++ + C G P P V W + D++ + L++++ +D G Y CIA Sbjct: 791 ESASVFC-NATGHPAPAVQWVRK--------DTQQKMSGEPELILENIMPSDGGFYSCIA 841 Query: 183 RNAAGT 188 N GT Sbjct: 842 TNIVGT 847 >UniRef50_Q4S556 Cluster: Chromosome 6 SCAF14737, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 6 SCAF14737, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1089 Score = 100 bits (239), Expect = 3e-19 Identities = 96/304 (31%), Positives = 134/304 (44%), Gaps = 35/304 (11%) Query: 20 DVTVARHQPATLNCRAGGS-PSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77 ++ V A + C S P +R+ K L S + I+P+G L AT Sbjct: 165 EIEVDEGNTAVIECHLPESQPKAQVRYSVKQEWLETSKGNYLIMPSGNLQIANATQ---- 220 Query: 78 SDAGVYWCEATN----------SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127 D G Y C A N S R R +T A R + S + +G +VL Sbjct: 221 EDEGPYKCAAYNPVTQEVKTSISADRLRIRRSTSEAA--RIIYPPASRSIMATKGQRLVL 278 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 EC+ G P P V W K+GQ L + ++R L NL+I ++D+G Y C A N Sbjct: 279 ECVAS-GIPTPQVTWAKDGQDLRYVNNTRFLL---SNLLIDAVGESDSGTYACQADNGIL 334 Query: 188 TRESAIATLKIHI-KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 SA+ + + +P +T ++ G +V F C+ G P P V W +A + P Sbjct: 335 ASASAMVLYNVQVSEPPQVT--VELQQVYGGTVRFTCQARGKPAPSVTWLHNARPLS-PS 391 Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--------PPSINLS 298 R + L LR+ NV L DEG Y C AEN VG+ AS L + PPSI LS Sbjct: 392 PRHR-LTSRMLRVSNVGLQDEGLYQCMAENGVGSSQASARLIIASAVVPPRGKPPSIFLS 450 Query: 299 PNSV 302 P+ V Sbjct: 451 PDKV 454 Score = 98.3 bits (234), Expect = 1e-18 Identities = 89/333 (26%), Positives = 144/333 (43%), Gaps = 31/333 (9%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGGLFF 68 E P E+P V +L C A P+ A I W G ++ ++L L+ Sbjct: 64 EVPVFTEEPASVVQKLGGSVSLRCSA--RPALANISWRLNGQELLDGDFGAVLGPNSLYI 121 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GDTV 125 ++ + G Y C A+ G S A + A LR+ EP+ Q + G+T Sbjct: 122 PSLSNLTL----GRYQCVASTGVGALASVLANVTAAKLRD---FEPDDHQEIEVDEGNTA 174 Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185 V+EC P P+ V + Q L ++ GNL I +A Q D G Y+C A N Sbjct: 175 VIECHLPESQPKAQVRYSVK-QEWLETSKGNYLIMPSGNLQIANATQEDEGPYKCAAYNP 233 Query: 186 AGTR-ESAIATLKIHIK------PYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 +++I+ ++ I+ +I P ++A G + +C G P P V W Sbjct: 234 VTQEVKTSISADRLRIRRSTSEAARIIYPPASRSIMATKGQRLVLECVASGIPTPQVTWA 293 Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYL---TVYDPP 293 + G + + L +L +D V +D G Y+C+A+N + A +++ L V +PP Sbjct: 294 KD-GQDLRYVNNTRFL-LSNLLIDAVGESDSGTYACQADNGILASASAMVLYNVQVSEPP 351 Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326 + + V G RFTC A G+P P++ W Sbjct: 352 QVTVELQQV---YGGTVRFTCQARGKPAPSVTW 381 Score = 77.4 bits (182), Expect = 2e-12 Identities = 91/393 (23%), Positives = 148/393 (37%), Gaps = 33/393 (8%) Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169 F EP S G +V L C N+ W+ NGQ LL DGD ++ +L I Sbjct: 68 FTEEPASVVQKLGGSVSLRCSARPALA--NISWRLNGQELL-DGDFGA-VLGPNSLYIPS 123 Query: 170 ARQTDAGRYQCIARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVG-G 227 GRYQC+A G S +A + ++ + +++ G++ +C + Sbjct: 124 LSNLTLGRYQCVASTGVGALASVLANVTAAKLRDFEPDDHQEIEVDEGNTAVIECHLPES 183 Query: 228 DPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG-----AVS 282 P V + G ++ G+L++ N DEG Y C A N V ++S Sbjct: 184 QPKAQVRYSVKQEWLETSKGNYLIMPSGNLQIANATQEDEGPYKCAAYNPVTQEVKTSIS 243 Query: 283 ASGYL---TVYDPPSINLSP--NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337 A + + I P S+ G C A+G P P + W+ +G Sbjct: 244 ADRLRIRRSTSEAARIIYPPASRSIMATKGQRLVLECVASGIPTPQVTWAKDG------- 296 Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397 +D + ++ L I+ ++DS T C A N G + + + P Sbjct: 297 ---QDLRYVNNTRFLLSNLLIDAVGESDS-GTYACQADN--GILASASAMVLYNVQVSEP 350 Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL 457 P +T F C A P P + W L + R +T+ L + ++ Sbjct: 351 PQVT---VELQQVYGGTVRFTCQARGKPAPSVTWLHNARPLSPSPRHRLTS-RMLRVSNV 406 Query: 458 DKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490 D G Y C+A + G S L++ S + P Sbjct: 407 GLQDEGLYQCMAENGVGSSQASARLIIASAVVP 439 Score = 40.3 bits (90), Expect = 0.31 Identities = 57/239 (23%), Positives = 94/239 (39%), Gaps = 30/239 (12%) Query: 492 IHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGN 551 + F A + P P KP T+TS ++W G I ++VE + + +G Sbjct: 628 VPFHTAPPPPAAPEAPDKPTVSAATETSAYVTWIPRGNRG-FPIQSFRVE-YKKVKKAGE 685 Query: 552 NTPRNSRGWVVIARRVHQTHYVVK--SLIPGITYMFIVRTENSHGLSGPSPVSD--SVTV 607 + WV + + V+ L G +Y F V N G S PS S +V V Sbjct: 686 D-------WVTAVENIPPSRLSVEITGLEKGTSYKFRVVAVNVIGSSPPSAPSKAYAVVV 738 Query: 608 GDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIY 667 G +G ++ Y I I+ TP+++ I G +IY Sbjct: 739 GRTPERPVDGPYIT----YNEAINETSIILKWTYTPVNNTPI------------YGFYIY 782 Query: 668 FRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQT 726 +RP D+ + + K + D IT+L+ T Y+ + F +K E + N + +T Sbjct: 783 YRPTDSDN-DSDYKKDVVEGDKYWHSITNLQPETAYDIKMQSFNEKGESEFGNVVILET 840 >UniRef50_UPI0000E4A8AD Cluster: PREDICTED: similar to Ptprd protein, partial; n=5; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Ptprd protein, partial - Strongylocentrotus purpuratus Length = 1773 Score = 99 bits (238), Expect = 4e-19 Identities = 133/537 (24%), Positives = 211/537 (39%), Gaps = 75/537 (13%) Query: 293 PSINLSPNS-VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 P I +P + VE+ A C ATG PEP + W E P + D+ T Sbjct: 70 PEITSNPRRYMVVENNRPATIYCGATGNPEPEILWFKE-----FVPIEANDRISMTDSGL 124 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411 + ++D + + C+A N G+ + + V D + P T P NQ + Sbjct: 125 QFSRAQLSDQGRYE------CAAKNSLGTRY-SVEAQVYVKDRQVEPRFTILPENQEVVP 177 Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471 C A +P P + W G L + G VL+ D +S YTCVA+S Sbjct: 178 GGSVNLTCAAYGSPMPRVRWMKAGMDLDDMDDLPI---GRNVLQLRDIYESANYTCVATS 234 Query: 472 RHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIG 531 G +D+ V + P P P+ T +S+T+ WS + Sbjct: 235 LLGT--------IDTSAR--------VTVRTRPSVPNSPVVTGYTSSSLTVEWST---LS 275 Query: 532 SSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTEN 591 S ++ + +E + R G+ T T + ++ L+P Y + N Sbjct: 276 SDTVTSHVLE-YKRSRSGGSFTEMEIPS-------PQDTSFTIEGLLPYTEYAVRLLAVN 327 Query: 592 SHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKL 651 S G S PS D VT G V + E E I + I+L Sbjct: 328 SIGRSNPS---DEVTA-------MTGEDVPSQPEQ------------FEGVAISASQIRL 365 Query: 652 MWEILNFYYLEGLFIYFRPLDNI-TIEYEM-KTILHSNDVSGFEITSLRKYTKYEFFLIP 709 W + + E I + N+ T + +M KTI + D + + +LR T Y L Sbjct: 366 TWMMRD---TEPQIIRYELYYNVSTNDNDMHKTITPTTD---YVLDNLRPNTLYHIRLAA 419 Query: 710 FYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNV 769 + EG S +T P PP + +L++T++ ++WSPP L+ QNG ITGY + Sbjct: 420 RSETGEGASSPVITVRTQQSAPGAPPQEVSGTVLSSTSIEVRWSPPPLEDQNGDITGYKI 479 Query: 770 VVNWLDVPANKSMVAINTTVH-QATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825 + + + + + +N V S I+ L Y +++ A T IG GP S + Sbjct: 480 IYRKMSLVSTNN-PEMNVPVEADVRSYILEALRKYTLYDIRVVACTAIGDGPPSDSL 535 Score = 93.1 bits (221), Expect = 4e-17 Identities = 85/284 (29%), Positives = 132/284 (46%), Gaps = 18/284 (6%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80 + V ++PAT+ C A G+P P I W+K V + ++ S+ + GL F RA SD Sbjct: 80 MVVENNRPATIYCGATGNPEPEILWFKEFVPIEANDRISMTDS-GLQFSRAQ----LSDQ 134 Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREE--FRLEPESKQSAQGDTVVLECLPPRGSPEP 138 G Y C A NS GT S A ++V + E F + PE+++ G +V L C GSP P Sbjct: 135 GRYECAAKNSLGTRYSVEAQVYVKDRQVEPRFTILPENQEVVPGGSVNLTC-AAYGSPMP 193 Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198 V W K G L D L G N V+Q ++ Y C+A + GT +++ A + + Sbjct: 194 RVRWMKAGMDL----DDMDDLPIGRN-VLQLRDIYESANYTCVATSLLGTIDTS-ARVTV 247 Query: 199 HIKPYLITGPEDVVAQTGSSVTFQ-CRVGGDPLPD-VL-WRRSAGGGNMPLGRVKVLDDG 255 +P + P V T SS+T + + D + VL ++RS GG+ + D Sbjct: 248 RTRPSVPNSPV-VTGYTSSSLTVEWSTLSSDTVTSHVLEYKRSRSGGSFTEMEIPSPQDT 306 Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299 S ++ ++ E A NS+G + S +T + P Sbjct: 307 SFTIEGLLPYTEYAVRLLAVNSIGRSNPSDEVTAMTGEDVPSQP 350 Score = 78.6 bits (185), Expect = 1e-12 Identities = 46/163 (28%), Positives = 82/163 (50%), Gaps = 6/163 (3%) Query: 661 LEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN 720 + G I +R + ++ + DV + + +LRKYT Y+ ++ +G PS+ Sbjct: 474 ITGYKIIYRKMSLVSTNNPEMNVPVEADVRSYILEALRKYTLYDIRVVACTAIGDGPPSD 533 Query: 721 SRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNV----VVNWLDV 776 S +T +D P+GPP + + + N+TT+ ++W P+ LQNG I GY + V D Sbjct: 534 SLSIRTAEDAPEGPPRKVRVRVHNSTTIRVQWQAPDPDLQNGEIRGYRIDYQTVTEEGDP 593 Query: 777 PANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819 + ++ IN ++++L YS++IAA T+ G G Sbjct: 594 VGSPQVLFINQP--DLRVAVLSDLLPKTFYSIEIAAFTVRGDG 634 Score = 62.9 bits (146), Expect = 5e-08 Identities = 39/142 (27%), Positives = 70/142 (49%), Gaps = 9/142 (6%) Query: 684 LHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDD-VPDGPPINIEMFI 742 L ++ + LR T+YEF L + EG + + T + P G P+N+ Sbjct: 698 LRPSEFQSYTFDDLRLGTRYEFKLTASNE--EGNSNEAIFYYTTHEGTPSGSPMNVTASP 755 Query: 743 LNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTS 802 L+++++ + W PP + +NG+I Y + +P + N T T +++T+L Sbjct: 756 LSSSSISVSWDPPLEEERNGLILKYTIRYYSSAMPTELT----NRTTE--TDIVLTSLVP 809 Query: 803 GVSYSVQIAAETIIGLGPFSQK 824 +YSV++ A T +G GP+S K Sbjct: 810 NTAYSVEVRAHTSVGPGPYSTK 831 Score = 60.1 bits (139), Expect = 4e-07 Identities = 55/219 (25%), Positives = 91/219 (41%), Gaps = 26/219 (11%) Query: 202 PYLITGPED-VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSL 257 P + + P +V + T C G+P P++LW + +P+ R+ + D G L Sbjct: 70 PEITSNPRRYMVVENNRPATIYCGATGNPEPEILWFKEF----VPIEANDRISMTDSG-L 124 Query: 258 RLDNVILADEGEYSCEAENSVGA-VSASGYLTVYD---PPSINLSPNSVNVESGNVARFT 313 + L+D+G Y C A+NS+G S + V D P + P + V G T Sbjct: 125 QFSRAQLSDQGRYECAAKNSLGTRYSVEAQVYVKDRQVEPRFTILPENQEVVPGGSVNLT 184 Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373 C A G P P + W + GM D + G VL + D +S N C Sbjct: 185 CAAYGSPMPRVRW--------MKAGMDLDDMDDLPI--GRNVLQLRDI--YESAN-YTCV 231 Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412 A + G+ ++TV + P + G ++ +L ++ Sbjct: 232 ATSLLGTIDTSARVTVRTRPSVPNSPVVTGYTSSSLTVE 270 >UniRef50_UPI000065CE26 Cluster: Homolog of Homo sapiens "Hemicentin; n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens "Hemicentin - Takifugu rubripes Length = 632 Score = 99 bits (238), Expect = 4e-19 Identities = 80/295 (27%), Positives = 116/295 (39%), Gaps = 21/295 (7%) Query: 13 YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-----DTHRS----ILPA 63 +II P ++TV +++C GG P P + W+K G L+ + H + + + Sbjct: 95 HIIHGPDNITVTLATEVSMHCTVGGFPVPTVHWFKDGCLLTNCSASFSLHNNGQLLTIMS 154 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123 G F + H + CE A + V + F P + QG+ Sbjct: 155 GTCFSFYSFKKTNHKTKLIICCELVAFVQLA--NKTCVMVPEMDWSFVQHPANMTVKQGE 212 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQ--------TLLFDGDSRMHLVDGGNLVIQDARQTDA 175 V + C PP P V W KN Q +L GD + L I+ R D Sbjct: 213 NVTVVCRPPCSRPTAQVSWFKNNQLYIPTNHVAVLPSGDLFFQRLRNTTLHIESVRIYDE 272 Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVL 234 G Y C+A NA G A A L + + P ++T V G V CR VG +P+ Sbjct: 273 GVYVCVASNALGQSNDA-ALLTVAVSPIIVTFLSRVSTLIGDLVVLPCRAVGIEPITYTW 331 Query: 235 WRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 + P G +DG+LR+ +D GEY C AEN G LT+ Sbjct: 332 TKGKEEDPISPAGDKHTDEDGALRISTTQQSDAGEYYCTAENRAGRHQRRAILTI 386 Score = 53.2 bits (122), Expect = 4e-05 Identities = 55/196 (28%), Positives = 86/196 (43%), Gaps = 20/196 (10%) Query: 208 PEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGNMPLGRVKVLDDG----------S 256 P ++ + G +VT CR P V W ++ +P V VL G + Sbjct: 203 PANMTVKQGENVTVVCRPPCSRPTAQVSWFKN-NQLYIPTNHVAVLPSGDLFFQRLRNTT 261 Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316 L +++V + DEG Y C A N++G + + LTV P I + V+ G++ C A Sbjct: 262 LHIESVRIYDEGVYVCVASNALGQSNDAALLTVAVSPIIVTFLSRVSTLIGDLVVLPCRA 321 Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376 G T W+ I P + DK+ DG L I+ T ++D+ C+A N Sbjct: 322 VGIEPITYTWTKGKEEDPISP--AGDKHTDE---DG--ALRISTTQQSDA-GEYYCTAEN 373 Query: 377 YAGSSFVRGKLTVTSD 392 AG R LT+T++ Sbjct: 374 RAGRHQRRAILTITAE 389 Score = 42.7 bits (96), Expect = 0.059 Identities = 35/123 (28%), Positives = 53/123 (43%), Gaps = 9/123 (7%) Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA 430 VC A N G S LTV PII S + I + V PC A+ EPI Sbjct: 276 VCVASNALGQSNDAALLTVAVS-----PIIVTFLSRVSTLIGDLVVLPCRAVGI-EPITY 329 Query: 431 WYFEG---EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 + +G + + ++ DG L + +SD+G Y C A +R G++ L + + Sbjct: 330 TWTKGKEEDPISPAGDKHTDEDGALRISTTQQSDAGEYYCTAENRAGRHQRRAILTITAE 389 Query: 488 INP 490 +P Sbjct: 390 HHP 392 >UniRef50_P34082 Cluster: Fasciclin-2 precursor; n=7; Diptera|Rep: Fasciclin-2 precursor - Drosophila melanogaster (Fruit fly) Length = 873 Score = 99 bits (238), Expect = 4e-19 Identities = 100/415 (24%), Positives = 168/415 (40%), Gaps = 36/415 (8%) Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140 G Y+C A+ + + T+ V + PE++ G V+ C + P P + Sbjct: 112 GKYYCTASYANTEILEKGVTIKTYVAIT-WTNAPENQYPTLGQDYVVMC-EVKADPNPTI 169 Query: 141 YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH- 199 W +NG + D ++V L+I++ +++D G Y C A T E T+++ Sbjct: 170 DWLRNGDPIRTTNDK--YVVQTNGLLIRNVQESDEGIYTCRAA-VIETGELLERTIRVEV 226 Query: 200 -IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKV-LDDGS 256 I+P +I+ P ++ A G C G P+P++ W R A N+ R +V G Sbjct: 227 FIQPEIISLPTNLEAVEGKPFAANCTARGKPVPEISWIRDATQLNVATADRFQVNPQTGL 286 Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316 + + +V D G Y+C A+N G V L V P I N + +A TC A Sbjct: 287 VTISSVSQDDYGTYTCLAKNRAGVVDQKTKLNVLVRPQIYELYNVTGARTKEIA-ITCRA 345 Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRD--KYHATAVFD-----GVTVLTINDTDKNDSRNT 369 GRP P + + G + G D + FD L I++ +++D Sbjct: 346 KGRPAPAITFRRWGTQEEYTNGQQDDDPRIILEPNFDEERGESTGTLRISNAERSDD-GL 404 Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDD-----RPPPIITNGPSNQTLPIKSMAVFPCTAICT 424 C A N ++ G +TV D PP+ + L C A+ Sbjct: 405 YQCIARNKGADAYKTGHITVEFAPDFSHMKELPPVFSWEQRKANL--------SCLAMGI 456 Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGT-----LVLKDLDKSDSGTYTCVASSRHG 474 P I W++ G + + N+ GT L++ + + Y C+A++ HG Sbjct: 457 PNATIEWHWNGRKIKDLYDTNLKIVGTGPRSDLIVHPVTRQYYSGYKCIATNIHG 511 Score = 85.4 bits (202), Expect = 8e-15 Identities = 78/325 (24%), Positives = 124/325 (38%), Gaps = 27/325 (8%) Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86 Q + C P+P I W + G + + + ++ GL SD G+Y C Sbjct: 153 QDYVVMCEVKADPNPTIDWLRNGDPIRTTNDKYVVQTNGLLIRNVQ----ESDEGIYTCR 208 Query: 87 ATNSYGTARSRNATLHVAV-LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145 A T T+ V V ++ E P + ++ +G C RG P P + W ++ Sbjct: 209 AA-VIETGELLERTIRVEVFIQPEIISLPTNLEAVEGKPFAANC-TARGKPVPEISWIRD 266 Query: 146 GQTLLFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL 204 L R + G + I Q D G Y C+A+N AG + L + ++P + Sbjct: 267 ATQLNVATADRFQVNPQTGLVTISSVSQDDYGTYTCLAKNRAGVVDQK-TKLNVLVRPQI 325 Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK-----VLD------ 253 A+T + CR G P P + +RR G+ +L+ Sbjct: 326 YELYNVTGART-KEIAITCRAKGRPAPAITFRRWGTQEEYTNGQQDDDPRIILEPNFDEE 384 Query: 254 ----DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES--G 307 G+LR+ N +D+G Y C A N +G++TV P + V S Sbjct: 385 RGESTGTLRISNAERSDDGLYQCIARNKGADAYKTGHITVEFAPDFSHMKELPPVFSWEQ 444 Query: 308 NVARFTCTATGRPEPTMFWSVEGNR 332 A +C A G P T+ W G + Sbjct: 445 RKANLSCLAMGIPNATIEWHWNGRK 469 Score = 54.8 bits (126), Expect = 1e-05 Identities = 53/189 (28%), Positives = 79/189 (41%), Gaps = 23/189 (12%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHR-SILPAGGLFFL 69 P II P ++ +P NC A G P P I W + L V+ R + P GL + Sbjct: 230 PEIISLPTNLEAVEGKPFAANCTARGKPVPEISWIRDATQLNVATADRFQVNPQTGLVTI 289 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129 + D G Y C A N G + L+V V + + L + A+ + + C Sbjct: 290 SSVS---QDDYGTYTCLAKNRAGVV-DQKTKLNVLVRPQIYEL--YNVTGARTKEIAITC 343 Query: 130 LPPRGSPEPNVYWKKNGQTLLF-----DGDSRMHLVDG---------GNLVIQDARQTDA 175 +G P P + +++ G + D D R+ L G L I +A ++D Sbjct: 344 -RAKGRPAPAITFRRWGTQEEYTNGQQDDDPRIILEPNFDEERGESTGTLRISNAERSDD 402 Query: 176 GRYQCIARN 184 G YQCIARN Sbjct: 403 GLYQCIARN 411 Score = 44.8 bits (101), Expect = 0.015 Identities = 25/92 (27%), Positives = 40/92 (43%) Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS 460 TN P NQ + V C P P I W G+ + + + V L+++++ +S Sbjct: 141 TNAPENQYPTLGQDYVVMCEVKADPNPTIDWLRNGDPIRTTNDKYVVQTNGLLIRNVQES 200 Query: 461 DSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492 D G YTC A+ + + V+ I P I Sbjct: 201 DEGIYTCRAAVIETGELLERTIRVEVFIQPEI 232 >UniRef50_Q9W4Y3 Cluster: CG33950-PF, isoform F; n=13; Coelomata|Rep: CG33950-PF, isoform F - Drosophila melanogaster (Fruit fly) Length = 4629 Score = 99.5 bits (237), Expect = 5e-19 Identities = 109/403 (27%), Positives = 164/403 (40%), Gaps = 53/403 (13%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 LNC+ S W G + S R++ G +R SD+GVY C A + Sbjct: 3073 LNCQFTSVASLRYDWSHNGRSLSSSPARNVEIRGNTLEVRDAS---ESDSGVYTCVAYD- 3128 Query: 91 YGTARSRNATLHVAVLREE---FRLEP--ESKQS----AQGDTVVLECLPPRGSPEPNVY 141 T R+ + V + R E F +P ES + QG+ + C GSP P++ Sbjct: 3129 VRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITC-EASGSPYPSIK 3187 Query: 142 WKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201 W K + +H + G L I AR + G Y C+A N G S +++ I I+ Sbjct: 3188 WAKVHDFM----PENVH-ISGNVLTIYGARFENRGVYSCVAENDHG---SDLSSTSIDIE 3239 Query: 202 PY------LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255 P +++ P + G+ + C V G P P V W R G P R K+ G Sbjct: 3240 PRERPSVKIVSAPLQTFS-VGAPASLYCTVEGIPDPTVEWVRVDGQPLSP--RHKIQSPG 3296 Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS--VNVESGNVARFT 313 + +D++ L D G+Y C A+N VG + +TV +P + + P++ + + G+ T Sbjct: 3297 YMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLT 3356 Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373 C +G P P + W E + RD Y + +L I K D+ C Sbjct: 3357 CVGSGVPNPEVEWVNE-------MALKRDLYSPPS---NTAILKIYRVTKADA-GIYTCH 3405 Query: 374 AVNYAGSSFV---------RGKLTVTSDDDRPPPIITNGPSNQ 407 N AGS RG + DD PI N P Q Sbjct: 3406 GKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQ 3448 Score = 84.6 bits (200), Expect = 1e-14 Identities = 112/483 (23%), Positives = 187/483 (38%), Gaps = 53/483 (10%) Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73 I+ P VT + + C G+P+P + W + V +D + L F Sbjct: 2960 IVNLPSHVTFEEYVNNEIICEVLGNPAPRVTWAR--VDGHADAQSTRTYDNRLIF----D 3013 Query: 74 GRVHSDAGVYWCEATN------SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127 SD G Y C+A N Y ++ ++ + PE G++ L Sbjct: 3014 SPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQL 3073 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 C W NG++ L +R + G L ++DA ++D+G Y C+A + Sbjct: 3074 NC-QFTSVASLRYDWSHNGRS-LSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVR- 3130 Query: 188 TRESAIATLKIHI----------KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 TR + + +++I KP + + ++++ G + C G P P + W + Sbjct: 3131 TRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAK 3190 Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV--YDPPSI 295 MP V + L + + G YSC AEN G+ +S + + + PS+ Sbjct: 3191 V--HDFMP-ENVHI-SGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSV 3246 Query: 296 NLSPNSVNVES-GNVARFTCTATGRPEPTMFW-SVEGNRTIIFPGMSRDKYHATAVFDGV 353 + + S G A CT G P+PT+ W V+G P R K + Sbjct: 3247 KIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQ-----PLSPRHKIQSPG----- 3296 Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK- 412 + I+D DS C A N G + G T+T + P ++ P N+ L + Sbjct: 3297 -YMVIDDIQLEDS-GDYECRAKNIVGEA--TGVATITVQE---PTLVQIIPDNRDLRLTE 3349 Query: 413 -SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471 C P P + W E AL ++ +N L + + K+D+G YTC + Sbjct: 3350 GDELSLTCVGSGVPNPEVEWVNE-MALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKN 3408 Query: 472 RHG 474 G Sbjct: 3409 EAG 3411 Score = 78.6 bits (185), Expect = 1e-12 Identities = 115/502 (22%), Positives = 190/502 (37%), Gaps = 61/502 (12%) Query: 15 IEQPLDVTVARHQPATLNC--RAGGSPSPAI-RWYKGGVLVVSDTHRSILPAGGLFFLRA 71 I++P V TL+C R S SP I WYK S ++ GG +L Sbjct: 2864 IQKPEITIVPVGGSMTLSCSGRMRWSNSPVIVNWYKEN----SRLPENVEVQGGNLYL-- 2917 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131 + SD+GVY C+A N+ TA T+ + + +++ +L P + E + Sbjct: 2918 -YDLQVSDSGVYICQAVNNE-TASVFKDTVSITITKKD-QLSPAEIVNLPSHVTFEEYVN 2974 Query: 132 PR------GSPEPNVYWKKNGQTLLFDG--DSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183 G+P P V W + DG D++ L+ R++D GRY+C A Sbjct: 2975 NEIICEVLGNPAPRVTWAR------VDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAE 3028 Query: 184 NAAGTRESAIATLKIHIKPY-------LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236 N E + P L PE++ G S C+ W Sbjct: 3029 NDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLRYDWS 3088 Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEA----------ENSVGAVSASGY 286 + + R + +L + + +D G Y+C A E++ + Sbjct: 3089 HNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREE 3148 Query: 287 LTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHA 346 + P I ++ + G TC A+G P P++ W+ + P + H Sbjct: 3149 QPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHD---FMP----ENVHI 3201 Query: 347 TAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN 406 + VLTI + ++R C A N GS + + +RP I + P Sbjct: 3202 SG-----NVLTIYGA-RFENRGVYSCVAENDHGSDLSSTSIDI-EPRERPSVKIVSAPL- 3253 Query: 407 QTLPIKSMAVFPCTAICTPEPIIAWY-FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465 QT + + A CT P+P + W +G+ L H+ + + G +V+ D+ DSG Y Sbjct: 3254 QTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHK--IQSPGYMVIDDIQLEDSGDY 3311 Query: 466 TCVASSRHGKYVWSGALLVDSP 487 C A + G+ + V P Sbjct: 3312 ECRAKNIVGEATGVATITVQEP 3333 Score = 78.2 bits (184), Expect = 1e-12 Identities = 75/283 (26%), Positives = 121/283 (42%), Gaps = 27/283 (9%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68 G P I ++ + + + ++ C A GSP P+I+W K + + H S G + Sbjct: 3152 GNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMPENVHIS----GNVLT 3207 Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS-AQGDTVVL 127 + +G + GVY C A N +G+ S + R ++ Q+ + G L Sbjct: 3208 I---YGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSAPLQTFSVGAPASL 3264 Query: 128 ECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186 C G P+P V W + +GQ L R + G +VI D + D+G Y+C A+N Sbjct: 3265 YC-TVEGIPDPTVEWVRVDGQPL----SPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIV 3319 Query: 187 GTRESAIATLKIHIKPYL---ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243 G + +AT+ + +P L I D+ G ++ C G P P+V W Sbjct: 3320 G-EATGVATITVQ-EPTLVQIIPDNRDLRLTEGDELSLTCVGSGVPNPEVEW-----VNE 3372 Query: 244 MPLGR---VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSA 283 M L R + L++ V AD G Y+C +N G+ A Sbjct: 3373 MALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEA 3415 Score = 68.5 bits (160), Expect = 1e-09 Identities = 85/358 (23%), Positives = 140/358 (39%), Gaps = 36/358 (10%) Query: 160 VDGGNLVIQDARQTDAGRYQCIARN--AAGTRESAIA---TLKIHIKP-YLITGPEDVVA 213 V GGNL + D + +D+G Y C A N A + ++ T K + P ++ P V Sbjct: 2910 VQGGNLYLYDLQVSDSGVYICQAVNNETASVFKDTVSITITKKDQLSPAEIVNLPSHVTF 2969 Query: 214 QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCE 273 + + C V G+P P V W R G + R D L D+ +DEG Y C+ Sbjct: 2970 EEYVNNEIICEVLGNPAPRVTWARVDGHADAQSTRTY---DNRLIFDSPRKSDEGRYRCQ 3026 Query: 274 AENSVGAVSASGYLTVY---DPPS-------INLSPNSVNVESGNVARFTCTATGRPEPT 323 AEN Y+ VY +PP + ++P +N +G + C T Sbjct: 3027 AENDQN--RDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLR 3084 Query: 324 MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR-NTIVCSAVNYAGSSF 382 WS G P + + G T L + D ++DS T V V + Sbjct: 3085 YDWSHNGRSLSSSPARNVE-------IRGNT-LEVRDASESDSGVYTCVAYDVRTRRNFT 3136 Query: 383 VRGKLTVTSDDDRP---PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI 439 ++ + +++P PII + N + C A +P P I W + + Sbjct: 3137 ESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMP 3196 Query: 440 QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRA 497 +N + L + + G Y+CVA + HG + S ++ ++ P++ A Sbjct: 3197 ENVH---ISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSA 3251 Score = 56.8 bits (131), Expect = 3e-06 Identities = 80/327 (24%), Positives = 125/327 (38%), Gaps = 44/327 (13%) Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESK--QSAQGDTVVLECLPPRGSP 136 AG Y C A N YG +R+ VAV + +F P+S+ + +G+ + L+C + Sbjct: 3603 AGEYRCSAFNQYG---NRSQIARVAVKKPADFHQVPQSQLQRHREGENIQLQCTV---TD 3656 Query: 137 EPNVYWKKNGQTLLFDGDSRM----HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192 + V + N + F D R D LV+ + R DAGRY C + + ++ Sbjct: 3657 QYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLP 3716 Query: 193 IATLK-------------IHIKPYLITGPEDVVAQ---------TGSSVTFQCRVGGDPL 230 ++ I++ P L D + G S +C D Sbjct: 3717 EVSIDLQVLTATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTY 3776 Query: 231 PDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY-LTV 289 DV+W RS G PL L + NV +D G Y C+ + G + + Y L V Sbjct: 3777 TDVVWERSDGA---PLSNNVRQVGNRLVISNVSPSDAGNYVCKCKTDEGDLYTTSYKLEV 3833 Query: 290 YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWS-----VEGNRTIIFPGMSRDKY 344 D P S V + G A C A +PT WS ++ R+++ +S D Sbjct: 3834 EDQPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSV 3893 Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIV 371 A + D + D N +V Sbjct: 3894 QANDAGTYICTAQYADGETADFPNILV 3920 Score = 41.5 bits (93), Expect = 0.14 Identities = 77/333 (23%), Positives = 114/333 (34%), Gaps = 44/333 (13%) Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73 II D+ + +L C G P+P + W L D + L R T Sbjct: 3338 IIPDNRDLRLTEGDELSLTCVGSGVPNPEVEWVNEMALK-RDLYSPPSNTAILKIYRVTK 3396 Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133 +DAG+Y C N G+ + HV V +E R + D + PP+ Sbjct: 3397 ----ADAGIYTCHGKNEAGSDEA-----HVRVEVQERRGDIGGVDD-DSDRDPINYNPPQ 3446 Query: 134 GSPEPNVYWKKNGQTLLFD-GDS-------------RMHLVDGG-----------NLVIQ 168 P ++ + Q L D GD+ R VDG L I Sbjct: 3447 -QQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIV 3505 Query: 169 DARQTDAGRYQCIARNAAGTRESA-IATLKIHIKPYLITGPE-DVVAQTGSSVTFQCRVG 226 Q + G+Y+C G ++ + L + P + P + + G ++ C+V Sbjct: 3506 RVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVEAGQNLDVHCQVE 3565 Query: 227 GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY 286 DV W N PL + LR ++ A GEY C A N G S Sbjct: 3566 NVRPEDVHWSTD---NNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIAR 3622 Query: 287 LTVYDPPSINLSPNS--VNVESGNVARFTCTAT 317 + V P + P S G + CT T Sbjct: 3623 VAVKKPADFHQVPQSQLQRHREGENIQLQCTVT 3655 Score = 38.7 bits (86), Expect = 0.96 Identities = 24/71 (33%), Positives = 33/71 (46%), Gaps = 3/71 (4%) Query: 204 LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVI 263 L T P+ + + V F+CR G V W R GG +P G +G L + N+ Sbjct: 1488 LKTYPDSQIIKESREVIFRCRDEGPARAKVKWSR-PGGRPLPPGFTD--RNGRLEIPNIR 1544 Query: 264 LADEGEYSCEA 274 + D G Y CEA Sbjct: 1545 VEDAGTYVCEA 1555 Score = 38.7 bits (86), Expect = 0.96 Identities = 30/99 (30%), Positives = 39/99 (39%), Gaps = 9/99 (9%) Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351 P I P SV++ V TC ATG P PT+ W + G DK + + + Sbjct: 1737 PLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNW-------GHVPDKCESKS-YG 1788 Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT 390 G L D DS C +N G+ FV VT Sbjct: 1789 GTGTLRCPDMRPQDS-GAYSCEIINTRGTHFVNPDTIVT 1826 Score = 35.5 bits (78), Expect = 8.9 Identities = 20/76 (26%), Positives = 34/76 (44%), Gaps = 2/76 (2%) Query: 419 CTAICTPEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC-VASSRHGKY 476 C A TP P I W G + ++ GTL D+ DSG Y+C + ++R + Sbjct: 1759 CVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTRGTHF 1818 Query: 477 VWSGALLVDSPINPNI 492 V ++ P+ ++ Sbjct: 1819 VNPDTIVTVRPVRTDV 1834 >UniRef50_UPI0000D55C03 Cluster: PREDICTED: similar to CG33484-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG33484-PA - Tribolium castaneum Length = 3764 Score = 99.1 bits (236), Expect = 6e-19 Identities = 122/521 (23%), Positives = 191/521 (36%), Gaps = 48/521 (9%) Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69 EAP D + T C G+P P + W+K G+ + ++ GL L Sbjct: 1352 EAPVFTSPLSDAIIQEGSRFTFMCHVTGTPVPVVTWFKDGISIQNNPDYQTTFDQGLCTL 1411 Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-------ESKQSAQG 122 D+ Y C+A N+ G+A + +A L V E +L P E + +G Sbjct: 1412 TIEE-TFAEDSAKYTCKAINAAGSAET-SACLSVKETEPEEQLSPPTFVKLLEPGSAREG 1469 Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD-ARQTDAGRYQCI 181 C G+P P V W KN + + D + +G ++ D D Y C Sbjct: 1470 AGFQFYC-KVEGNPLPTVQWFKNYECIDNSPDYVITYNNGEAILKFDKVSLEDKAEYTCK 1528 Query: 182 ARNAAGTRESA----IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 A N G +S + L+ P I +V+A+ G + +C V G P P + W Sbjct: 1529 ATNELGVAQSTASLTVTPLEPTEAPKFILPLSNVMARAGQKIKLECEVSGLPPPILTWTH 1588 Query: 238 SAGGGNMPLGRVKVL-------DDGSLRLDNVILADEGEYSCEAE---NSVGAVSASGYL 287 + + +L D G+ ++ +A E +C S S Sbjct: 1589 NGKALQFEGNKATLLVFEAFPKDAGTYVVNAKNIAGEASSACSVSVKGRLPTETSDSELA 1648 Query: 288 TVYDP--PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345 + +P PSI L +V+V GN R C G+PEP + W +R + ++ Sbjct: 1649 SDMEPVKPSIQLPLTNVSVTEGNRVRLDCVIVGQPEPEVIW-YHDDRPV------KESPD 1701 Query: 346 ATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPS 405 +F G I + A+N AG + + LTV D PP P Sbjct: 1702 FQLLFQGDRCSLIIQEALPEDAGQYKVVALNSAGEASSKCSLTVVPDSGTKPPEPEEPPG 1761 Query: 406 NQ---TLPIKSMAV-------FPCTAICTPEPIIAWYFEGEALIQNHRRNVT--NDGTLV 453 T + + V F P P I W + + +T +DGT+ Sbjct: 1762 TPPKFTKLLSDVLVSEGEKVEFEGCVTGEPTPEIKWLLNNQPITPTDHVKITHNSDGTIR 1821 Query: 454 LK--DLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492 L+ ++ D G YT A++ G L+V S P I Sbjct: 1822 LEIANVRPEDKGVYTVKATNSSGDAKCFAQLIVKSMKPPEI 1862 Score = 69.3 bits (162), Expect = 6e-10 Identities = 135/540 (25%), Positives = 202/540 (37%), Gaps = 73/540 (13%) Query: 15 IEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73 I+ PL +V+V L+C G P P + WY V +L G L Sbjct: 1658 IQLPLTNVSVTEGNRVRLDCVIVGQPEPEVIWYHDDRPVKESPDFQLLFQGDRCSLIIQE 1717 Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS-------------- 119 + DAG Y A NS G A S+ +L V EPE Sbjct: 1718 A-LPEDAGQYKVVALNSAGEASSK-CSLTVVPDSGTKPPEPEEPPGTPPKFTKLLSDVLV 1775 Query: 120 AQGDTVVLE-CLPPRGSPEPNVYWKKNGQTLL-FDGDSRMHLVDGG-NLVIQDARQTDAG 176 ++G+ V E C+ G P P + W N Q + D H DG L I + R D G Sbjct: 1776 SEGEKVEFEGCVT--GEPTPEIKWLLNNQPITPTDHVKITHNSDGTIRLEIANVRPEDKG 1833 Query: 177 RYQCIARNAAGTRESAIATLKIHIKPYLI-------TGPE------DVVAQTGSSVTFQC 223 Y A N++G + + +KP I +GP D VA G+S F+C Sbjct: 1834 VYTVKATNSSGDAKCFAQLIVKSMKPPEIIKHEEIKSGPSFKELFNDRVAFEGTSTKFEC 1893 Query: 224 RVGGDPLPDVLWRRSAGGGNMPLGRVKVL-----DDGSLRLDNVILADEGEYSCEAENSV 278 V G P P V W G GR K+L D L + + EG +C AEN V Sbjct: 1894 IVVGKPTPKVRW---LFNGEPITGR-KILISTSGDRQVLTIPEISKDLEGTITCVAENEV 1949 Query: 279 GAVSASGYLTVYDPPSINL----SPNSVNVESG-----NVARFTCTATGRPEPTMFWSVE 329 G S + +L+V +I L S +VES V + T+T R T F + Sbjct: 1950 GKASCAAHLSVQSVSTITLPEFSRDISQHVESSYILNREVHTQSSTSTSRKMET-FTGTQ 2008 Query: 330 GNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI---VCSAVNYAGSSFVRGK 386 + + +D+ + I+++ K + + + + + + S F G Sbjct: 2009 EPQVQVHSFSQKDQQSFKQI--NQEAPQISESHKIEEYHQVGKQPPTIIEKSSSLFTTGT 2066 Query: 387 LTVTSDDDRP----PPIITNGPSNQTLPIKSMAV-----FPCTAICTPEPI--IAWYFEG 435 T P+I P P+ V I +P I W G Sbjct: 2067 TEETKQKTIEHVVHKPVIKTRPPKFITPVMGKIVDQNVDVVLEGIVDGQPTPEITWTKNG 2126 Query: 436 EALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492 E L ++ + N ++V+K+ D+G YTC A + GK + + L+V + P + Sbjct: 2127 EQLRESSGVQIHFDRNKVSVVIKNATIDDAGRYTCTAVNEAGKAISTADLVVRKTVFPPV 2186 Score = 61.7 bits (143), Expect = 1e-07 Identities = 51/179 (28%), Positives = 77/179 (43%), Gaps = 8/179 (4%) Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQ 179 Q VVLE + G P P + W KNG+ L ++H ++VI++A DAGRY Sbjct: 2102 QNVDVVLEGIVD-GQPTPEITWTKNGEQLRESSGVQIHFDRNKVSVVIKNATIDDAGRYT 2160 Query: 180 CIARNAAGTRESA--IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237 C A N AG S + K P + V + G V + V G P P V W + Sbjct: 2161 CTAVNEAGKAISTADLVVRKTVFPPVFGRRLQAQVVKKGDRVIMEVEVTGTPDPTVTWYK 2220 Query: 238 SAGGGNMPLG---RVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292 LG R++ + + +L ++ L G + A NS G + + V++P Sbjct: 2221 DGVPIGEALGDKARIRSMGNSHTLVIEKAELNMSGRFMVRAVNSGGEAQSIADIAVFEP 2279 Score = 51.6 bits (118), Expect = 1e-04 Identities = 28/78 (35%), Positives = 40/78 (51%), Gaps = 3/78 (3%) Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQC 180 G EC+ + P PN+ W KNG+ + D ++H +G L I A DAG Y C Sbjct: 3590 GQPAKFECIV-QSEPPPNILWSKNGRIIENSNDYQLHYRNGVCRLTISQAYPEDAGTYAC 3648 Query: 181 IARNAAGTRESAIATLKI 198 A N+ GT + ATL++ Sbjct: 3649 TATNSVGT-VNTTATLEV 3665 Score = 51.2 bits (117), Expect = 2e-04 Identities = 32/97 (32%), Positives = 42/97 (43%), Gaps = 2/97 (2%) Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66 +S AP I ++ V QPA C P P I W K G ++ + + G+ Sbjct: 3571 SSARAPMFITPLRNIAVVSGQPAKFECIVQSEPPPNILWSKNGRIIENSNDYQLHYRNGV 3630 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103 L + DAG Y C ATNS GT + ATL V Sbjct: 3631 CRLTISQA-YPEDAGTYACTATNSVGTVNT-TATLEV 3665 Score = 50.8 bits (116), Expect = 2e-04 Identities = 47/184 (25%), Positives = 76/184 (41%), Gaps = 6/184 (3%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I + V ++ L G P+P I W K G + + I + Sbjct: 2089 PKFITPVMGKIVDQNVDVVLEGIVDGQPTPEITWTKNGEQLRESSGVQIHFDRNKVSVVI 2148 Query: 72 THGRVHSDAGVYWCEATNSYGTARS-RNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130 + + DAG Y C A N G A S + + V F +++ +GD V++E + Sbjct: 2149 KNATI-DDAGRYTCTAVNEAGKAISTADLVVRKTVFPPVFGRRLQAQVVKKGDRVIME-V 2206 Query: 131 PPRGSPEPNVYWKKNGQTL---LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 G+P+P V W K+G + L D + + LVI+ A +GR+ A N+ G Sbjct: 2207 EVTGTPDPTVTWYKDGVPIGEALGDKARIRSMGNSHTLVIEKAELNMSGRFMVRAVNSGG 2266 Query: 188 TRES 191 +S Sbjct: 2267 EAQS 2270 Score = 46.8 bits (106), Expect = 0.004 Identities = 36/138 (26%), Positives = 54/138 (39%), Gaps = 13/138 (9%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR------RSAGGGNMPLGRVKVLDDG 255 P IT + V + V G P P++ W R + G + R KV Sbjct: 2089 PKFITPVMGKIVDQNVDVVLEGIVDGQPTPEITWTKNGEQLRESSGVQIHFDRNKV---- 2144 Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLSPNSVNVESGNVARF 312 S+ + N + D G Y+C A N G ++ L V PP + V+ G+ Sbjct: 2145 SVVIKNATIDDAGRYTCTAVNEAGKAISTADLVVRKTVFPPVFGRRLQAQVVKKGDRVIM 2204 Query: 313 TCTATGRPEPTMFWSVEG 330 TG P+PT+ W +G Sbjct: 2205 EVEVTGTPDPTVTWYKDG 2222 Score = 45.6 bits (103), Expect = 0.008 Identities = 55/216 (25%), Positives = 82/216 (37%), Gaps = 21/216 (9%) Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL-PAGGLF 67 G P + DV V+ + G P+P I+W + H I + G Sbjct: 1761 GTPPKFTKLLSDVLVSEGEKVEFEGCVTGEPTPEIKWLLNNQPITPTDHVKITHNSDGTI 1820 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARS------RNATLHVAVLREEFRLEPESKQ--- 118 L + R D GVY +ATNS G A+ ++ + EE + P K+ Sbjct: 1821 RLEIANVR-PEDKGVYTVKATNSSGDAKCFAQLIVKSMKPPEIIKHEEIKSGPSFKELFN 1879 Query: 119 ---SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQT 173 + +G + EC+ G P P V W NG+ + G + G L I + + Sbjct: 1880 DRVAFEGTSTKFECIVV-GKPTPKVRWLFNGEPI--TGRKILISTSGDRQVLTIPEISKD 1936 Query: 174 DAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209 G C+A N G + S A L + IT PE Sbjct: 1937 LEGTITCVAENEVG-KASCAAHLSVQ-SVSTITLPE 1970 Score = 43.6 bits (98), Expect = 0.034 Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 2/95 (2%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL-- 259 P IT ++ +G F+C V +P P++LW ++ +G RL Sbjct: 3576 PMFITPLRNIAVVSGQPAKFECIVQSEPPPNILWSKNGRIIENSNDYQLHYRNGVCRLTI 3635 Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294 D G Y+C A NSVG V+ + L V PS Sbjct: 3636 SQAYPEDAGTYACTATNSVGTVNTTATLEVPGVPS 3670 Score = 43.2 bits (97), Expect = 0.044 Identities = 40/163 (24%), Positives = 63/163 (38%), Gaps = 14/163 (8%) Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377 G+P P + W+ G + R+ FD V + D C+AVN Sbjct: 2114 GQPTPEITWTKNGEQL-------RESSGVQIHFDRNKVSVVIKNATIDDAGRYTCTAVNE 2166 Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFE--- 434 AG + L V PP+ Q + + TP+P + WY + Sbjct: 2167 AGKAISTADLVVRKTVF--PPVFGRRLQAQVVKKGDRVIMEVEVTGTPDPTVTWYKDGVP 2224 Query: 435 -GEALIQNHR-RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 GEAL R R++ N TLV++ + + SG + A + G+ Sbjct: 2225 IGEALGDKARIRSMGNSHTLVIEKAELNMSGRFMVRAVNSGGE 2267 Score = 35.5 bits (78), Expect = 8.9 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 7/80 (8%) Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360 ++ V SG A+F C P P + WS G I + + H +GV LTI+ Sbjct: 3584 NIAVVSGQPAKFECIVQSEPPPNILWSKNGR---IIENSNDYQLHYR---NGVCRLTISQ 3637 Query: 361 TDKNDSRNTIVCSAVNYAGS 380 D+ T C+A N G+ Sbjct: 3638 AYPEDA-GTYACTATNSVGT 3656 >UniRef50_A7SQE0 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 178 Score = 99.1 bits (236), Expect = 6e-19 Identities = 58/180 (32%), Positives = 94/180 (52%), Gaps = 12/180 (6%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 ++T+ + A L C A GSP+P RW K G + S++ AGG + +T + SD Sbjct: 7 NLTLIAGETAVLQCTAAGSPTPYFRWLKSGKSLTMGGRMSVI-AGGSLMIEST---MASD 62 Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPEP 138 Y C+A N+ G+ + +++ V+ S QGDT+ L C +G P P Sbjct: 63 EANYTCQAVNNVGSV---HMAIYLEVIGPPNITSFRSSVTGVQGDTISLPCRA-KGFPPP 118 Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198 + W ++GQT+ +D R +D G L+I + +++D+G+Y C A N AG R+S T+ I Sbjct: 119 VITWSRSGQTIPYD---RRQSIDNGTLLIGNVQKSDSGKYTCTAVNTAGERDSVTMTVSI 175 Score = 97.5 bits (232), Expect = 2e-18 Identities = 55/158 (34%), Positives = 85/158 (53%), Gaps = 6/158 (3%) Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181 G+T VL+C GSP P W K+G++L G RM ++ GG+L+I+ +D Y C Sbjct: 13 GETAVLQCTAA-GSPTPYFRWLKSGKSLTMGG--RMSVIAGGSLMIESTMASDEANYTCQ 69 Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241 A N G+ AI L++ P + + V G +++ CR G P P + W RS G Sbjct: 70 AVNNVGSVHMAIY-LEVIGPPNITSFRSSVTGVQGDTISLPCRAKGFPPPVITWSRS--G 126 Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279 +P R + +D+G+L + NV +D G+Y+C A N+ G Sbjct: 127 QTIPYDRRQSIDNGTLLIGNVQKSDSGKYTCTAVNTAG 164 Score = 89.0 bits (211), Expect = 7e-16 Identities = 60/175 (34%), Positives = 85/175 (48%), Gaps = 15/175 (8%) Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAE 275 G + QC G P P W +S M GR+ V+ GSL +++ + +DE Y+C+A Sbjct: 13 GETAVLQCTAAGSPTPYFRWLKSGKSLTMG-GRMSVIAGGSLMIESTMASDEANYTCQAV 71 Query: 276 NSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII 335 N+VG+V + YL V PP+I +SV G+ C A G P P + WS G +TI Sbjct: 72 NNVGSVHMAIYLEVIGPPNITSFRSSVTGVQGDTISLPCRAKGFPPPVITWSRSG-QTI- 129 Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT 390 Y D T+L I + K+DS C+AVN AG R +T+T Sbjct: 130 -------PYDRRQSIDNGTLL-IGNVQKSDS-GKYTCTAVNTAGE---RDSVTMT 172 Score = 70.9 bits (166), Expect = 2e-10 Identities = 55/176 (31%), Positives = 81/176 (46%), Gaps = 16/176 (9%) Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359 +++ + +G A CTA G P P W G + MS V G +++ I Sbjct: 6 HNLTLIAGETAVLQCTAAGSPTPYFRWLKSGKSLTMGGRMS--------VIAGGSLM-IE 56 Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419 T +D N C AVN GS + L V PP IT+ S+ T PC Sbjct: 57 STMASDEAN-YTCQAVNNVGSVHMAIYLEVIG-----PPNITSFRSSVTGVQGDTISLPC 110 Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475 A P P+I W G+ + + R+++ N GTL++ ++ KSDSG YTC A + G+ Sbjct: 111 RAKGFPPPVITWSRSGQTIPYDRRQSIDN-GTLLIGNVQKSDSGKYTCTAVNTAGE 165 Score = 51.2 bits (117), Expect = 2e-04 Identities = 32/93 (34%), Positives = 44/93 (47%), Gaps = 2/93 (2%) Query: 406 NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465 N TL AV CTA +P P W G++L R +V G+L+++ SD Y Sbjct: 7 NLTLIAGETAVLQCTAAGSPTPYFRWLKSGKSLTMGGRMSVIAGGSLMIESTMASDEANY 66 Query: 466 TCVASSRHGKYVWSGALLVDSPINPNIHFFRAA 498 TC A + G + L V P PNI FR++ Sbjct: 67 TCQAVNNVGSVHMAIYLEVIGP--PNITSFRSS 97 Score = 40.7 bits (91), Expect = 0.24 Identities = 31/93 (33%), Positives = 40/93 (43%), Gaps = 7/93 (7%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I VT + +L CRA G P P I W + G + D +SI G L Sbjct: 89 PNITSFRSSVTGVQGDTISLPCRAKGFPPPVITWSRSGQTIPYDRRQSI-DNGTLLI--- 144 Query: 72 THGRVH-SDAGVYWCEATNSYGTARSRNATLHV 103 G V SD+G Y C A N+ G S T+ + Sbjct: 145 --GNVQKSDSGKYTCTAVNTAGERDSVTMTVSI 175 >UniRef50_Q9P2J2 Cluster: Protein turtle homolog A precursor; n=25; Tetrapoda|Rep: Protein turtle homolog A precursor - Homo sapiens (Human) Length = 1179 Score = 99.1 bits (236), Expect = 6e-19 Identities = 122/486 (25%), Positives = 187/486 (38%), Gaps = 53/486 (10%) Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182 + V L C+ RGSP P+V WK G+ L G ++ V G L I+ + +G Y C A Sbjct: 152 EPVTLRCVA-RGSPLPHVTWKLRGKDL-GQGQGQVQ-VQNGTLRIRRVERGSSGVYTCQA 208 Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRR---S 238 + G+ A L + P ++ P++ V+ C P W + + Sbjct: 209 SSTEGSATHATQLLVLG-PPVIVVPPKNSTVNASQDVSLACHAEAYPANLTYSWFQDNIN 267 Query: 239 AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSV-GAVSASGYLTVYDPPSINL 297 + RV++L DGSLRL D G Y+C N + SAS YLTV P + Sbjct: 268 VFHISRLQPRVRILVDGSLRLLATQPDDAGCYTCVPSNGLLHPPSASAYLTVLYPAQVTA 327 Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMF--WSVEGNRTII--FPGMSRDKYHATAVFDGV 353 P + G C P P +F W+ +G + FPG S+ +G Sbjct: 328 MPPETPLPIGMPGVIRCPVRANP-PLLFVSWTKDGKALQLDKFPGWSQGT-------EGS 379 Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP-IK 412 ++ + + D+ C+ N G++ G VT + PP P + + Sbjct: 380 LIIALGN---EDALGEYSCTPYNSLGTA---GPSPVTRVLLKAPPAFIERPKEEYFQEVG 433 Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472 + PC+A P P+++W G L + V ++ +L+L+ L K G + C AS+ Sbjct: 434 RELLIPCSAQGDPPPVVSWTKVGRGL--QGQAQVDSNSSLILRPLTKEAHGHWECSASNA 491 Query: 473 HGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGS 532 + S + V + + H V +LP +SW G Sbjct: 492 VARVATSTNVYV---LGTSPHVVTNVSVVALP-------------KGANVSWEP----GF 531 Query: 533 SSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENS 592 GY T R WV +A V H +V L P Y F V +N Sbjct: 532 DG--GYLQRFSVWYTPLAKRPDRMHHDWVSLAVPVGAAHLLVPGLQPHTQYQFSVLAQNK 589 Query: 593 HGLSGP 598 G SGP Sbjct: 590 LG-SGP 594 Score = 77.4 bits (182), Expect = 2e-12 Identities = 74/279 (26%), Positives = 109/279 (39%), Gaps = 13/279 (4%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSP-AIRWYKGGVLVVSDTH---RSILPAGGLF 67 P I+ P + TV Q +L C A P+ W++ + V + R + G Sbjct: 227 PVIVVPPKNSTVNASQDVSLACHAEAYPANLTYSWFQDNINVFHISRLQPRVRILVDGSL 286 Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127 L AT DAG Y C +N S +A L V + + PE+ G V+ Sbjct: 287 RLLATQP---DDAGCYTCVPSNGLLHPPSASAYLTVLYPAQVTAMPPETPLPI-GMPGVI 342 Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187 C P V W K+G+ L D G+L+I + G Y C N+ G Sbjct: 343 RCPVRANPPLLFVSWTKDGKALQLDKFPGWSQGTEGSLIIALGNEDALGEYSCTPYNSLG 402 Query: 188 TR-ESAIATLKIHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245 T S + + + P I P E+ + G + C GDP P V W + G Sbjct: 403 TAGPSPVTRVLLKAPPAFIERPKEEYFQEVGRELLIPCSAQGDPPPVVSWTKVGRGLQ-- 460 Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSAS 284 G+ +V + SL L + G + C A N+V V+ S Sbjct: 461 -GQAQVDSNSSLILRPLTKEAHGHWECSASNAVARVATS 498 Score = 75.8 bits (178), Expect = 7e-12 Identities = 94/372 (25%), Positives = 151/372 (40%), Gaps = 36/372 (9%) Query: 122 GDTVVLEC--LPPRGSPEPNVY-WKKNGQTL-LF----------DGD--SRMHLVDGGNL 165 G++VVL C LPP G P +V W + G L +F D D R+ L G +L Sbjct: 34 GESVVLGCDLLPPAGRPPLHVIEWLRFGFLLPIFIQFGLYSPRIDPDYVGRVRLQKGASL 93 Query: 166 VIQDARQTDAGRYQC-IARNAAGTRESAIAT-----LKIHIKP-YLITGPEDVVAQTGSS 218 I+ R D G Y+C + E A L ++ P + T P + Q Sbjct: 94 QIEGLRVEDQGWYECRVFFLDQHIPEDDFANGSWVHLTVNSPPQFQETPPAVLEVQELEP 153 Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSV 278 VT +C G PLP V W+ G+V+V +G+LR+ V G Y+C+A ++ Sbjct: 154 VTLRCVARGSPLPHVTWKLRGKDLGQGQGQVQV-QNGTLRIRRVERGSSGVYTCQASSTE 212 Query: 279 GAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPG 338 G+ + + L V PP I + P + V + C A P + + N + Sbjct: 213 GSATHATQLLVLGPPVIVVPPKNSTVNASQDVSLACHAEAYPANLTYSWFQDNINVFH-- 270 Query: 339 MSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398 +SR + + DG L D + + + + S+ LTV P Sbjct: 271 ISRLQPRVRILVDGSLRLLATQPDDAGCYTCVPSNGLLHPPSA--SAYLTVLY-----PA 323 Query: 399 IITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGEALIQNHRRNVT--NDGTLVLK 455 +T P LPI V C P + ++W +G+AL + + +G+L++ Sbjct: 324 QVTAMPPETPLPIGMPGVIRCPVRANPPLLFVSWTKDGKALQLDKFPGWSQGTEGSLIIA 383 Query: 456 DLDKSDSGTYTC 467 ++ G Y+C Sbjct: 384 LGNEDALGEYSC 395 Score = 72.9 bits (171), Expect = 5e-11 Identities = 83/336 (24%), Positives = 127/336 (37%), Gaps = 18/336 (5%) Query: 5 YVTSGEAPYIIEQPLDVT-VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63 ++T P E P V V +P TL C A GSP P + W G + + + Sbjct: 129 HLTVNSPPQFQETPPAVLEVQELEPVTLRCVARGSPLPHVTWKLRGKDLGQGQGQVQVQN 188 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123 G L R G +GVY C+A+++ G+A +AT + + + P++ Sbjct: 189 GTLRIRRVERG----SSGVYTCQASSTEGSA--THATQLLVLGPPVIVVPPKNSTVNASQ 242 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDG--DSRMHLVDGGNLVIQDARQTDAGRYQCI 181 V L C W ++ + R+ ++ G+L + + DAG Y C+ Sbjct: 243 DVSLACHAEAYPANLTYSWFQDNINVFHISRLQPRVRILVDGSLRLLATQPDDAGCYTCV 302 Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLWRRSAG 240 N SA A L + + P + G +C V PL V W + Sbjct: 303 PSNGLLHPPSASAYLTVLYPAQVTAMPPETPLPIGMPGVIRCPVRANPPLLFVSWTKD-- 360 Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADE---GEYSCEAENSVGAVSASGYLTVY--DPPSI 295 G + L + G+ + L +E GEYSC NS+G S V PP+ Sbjct: 361 GKALQLDKFPGWSQGTEGSLIIALGNEDALGEYSCTPYNSLGTAGPSPVTRVLLKAPPAF 420 Query: 296 NLSPNSVNV-ESGNVARFTCTATGRPEPTMFWSVEG 330 P E G C+A G P P + W+ G Sbjct: 421 IERPKEEYFQEVGRELLIPCSAQGDPPPVVSWTKVG 456 Score = 54.8 bits (126), Expect = 1e-05 Identities = 60/239 (25%), Positives = 97/239 (40%), Gaps = 28/239 (11%) Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEA----ENSVGAVSASG---YLTVYDPPSINLS 298 +GRV++ SL+++ + + D+G Y C ++ A+G +LTV PP + Sbjct: 82 VGRVRLQKGASLQIEGLRVEDQGWYECRVFFLDQHIPEDDFANGSWVHLTVNSPPQFQET 141 Query: 299 PNSV-NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357 P +V V+ C A G P P + W + G G + + V +G L Sbjct: 142 PPAVLEVQELEPVTLRCVARGSPLPHVTWKLRGKDL----GQGQGQVQ---VQNGT--LR 192 Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417 I ++ S C A + GS+ +L V PP+I P N T+ Sbjct: 193 IRRVERGSS-GVYTCQASSTEGSATHATQLLVLG-----PPVIVVPPKNSTVNASQDVSL 246 Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRR-----NVTNDGTLVLKDLDKSDSGTYTCVASS 471 C A P + +F+ + + R + DG+L L D+G YTCV S+ Sbjct: 247 ACHAEAYPANLTYSWFQDNINVFHISRLQPRVRILVDGSLRLLATQPDDAGCYTCVPSN 305 Score = 48.8 bits (111), Expect = 9e-04 Identities = 34/112 (30%), Positives = 50/112 (44%), Gaps = 6/112 (5%) Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG 435 ++A S+V LTV S PP P+ + C A +P P + W G Sbjct: 121 DFANGSWVH--LTVNS----PPQFQETPPAVLEVQELEPVTLRCVARGSPLPHVTWKLRG 174 Query: 436 EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 + L Q + +GTL ++ +++ SG YTC ASS G + LLV P Sbjct: 175 KDLGQGQGQVQVQNGTLRIRRVERGSSGVYTCQASSTEGSATHATQLLVLGP 226 >UniRef50_UPI00015B59DF Cluster: PREDICTED: similar to turtle protein; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to turtle protein - Nasonia vitripennis Length = 1402 Score = 98.7 bits (235), Expect = 8e-19 Identities = 83/334 (24%), Positives = 143/334 (42%), Gaps = 23/334 (6%) Query: 162 GGNLVIQDARQTDAGRYQC----IARNAAGTRESAIATLKIHIKPYLITGPEDVV-AQTG 216 G +L + + +++D G Y+C + R+ + L +H P PE+++ G Sbjct: 266 GASLNLTNIQESDQGWYECKVVFLNRSPNNNKNGTWFHLDVHAPPRFTITPEEMIYVNLG 325 Query: 217 SSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAE 275 ++ C+ G P P++LW + A P V +++DG+ LR+ + D G+Y+C A Sbjct: 326 DAIILNCQAEGTPTPEILWYKDANPVE-PSSTVTIINDGTELRISTIKTEDIGDYTCLAR 384 Query: 276 NSVGAVSASGYLTVYDPPSINLSP-NSVNVESGNVARFTCTATGRP-EPTMFWSVEGNRT 333 N G +S + + + I + P N +E NV F C A P T+ W EG Sbjct: 385 NGEGQISHTARVIIAGGAVITIPPQNETKLEGENVV-FPCEAKALPGNVTVSWYREG--- 440 Query: 334 IIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393 +S A+ DG L IN +DS T +C+ N G + Sbjct: 441 APISEVSELDTRASVRMDG--SLAINPVSADDS-GTYLCTVSNGIGEPQTASAYL----N 493 Query: 394 DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN---VTNDG 450 P +T P+ Q LP + V C P + + + L++ ++ V +G Sbjct: 494 VEYPAKVTFNPTVQYLPFRMAGVVQCYIKANPPLQYVTWTKDKRLLEPYQVKDIVVMGNG 553 Query: 451 TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 +L+ ++++ G YTC + HG SG + V Sbjct: 554 SLLFTRVNENHHGQYTCTPYNAHGTQGSSGYMEV 587 Score = 94.7 bits (225), Expect = 1e-17 Identities = 119/466 (25%), Positives = 185/466 (39%), Gaps = 45/466 (9%) Query: 39 PSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN-SYGTARSR 97 P+ + Y+G V VS P GG L T+ + SD G Y C+ + ++ Sbjct: 244 PTHSGEGYEGRVAKVSPNS----PYGGAS-LNLTNIQ-ESDQGWYECKVVFLNRSPNNNK 297 Query: 98 NAT-LHVAV-LREEFRLEPESKQSAQ-GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGD 154 N T H+ V F + PE GD ++L C G+P P + W K+ + + Sbjct: 298 NGTWFHLDVHAPPRFTITPEEMIYVNLGDAIILNC-QAEGTPTPEILWYKDANPV--EPS 354 Query: 155 SRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVA 213 S + ++ DG L I + D G Y C+ARN G + S A + I + P++ Sbjct: 355 STVTIINDGTELRISTIKTEDIGDYTCLARNGEG-QISHTARVIIAGGAVITIPPQNETK 413 Query: 214 QTGSSVTFQCRVGGDP-LPDVLWRRSAGGGNMPLGRVKVLD-------DGSLRLDNVILA 265 G +V F C P V W R P+ V LD DGSL ++ V Sbjct: 414 LEGENVVFPCEAKALPGNVTVSWYREGA----PISEVSELDTRASVRMDGSLAINPVSAD 469 Query: 266 DEGEYSCEAENSVGAV-SASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTM 324 D G Y C N +G +AS YL V P + +P + C P P Sbjct: 470 DSGTYLCTVSNGIGEPQTASAYLNVEYPAKVTFNPTVQYLPFRMAGVVQCYIKANP-PLQ 528 Query: 325 FWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR 384 + + ++ ++ P +D V ++L + + + T C+ N G+ Sbjct: 529 YVTWTKDKRLLEPYQVKD----IVVMGNGSLLFTRVNENHHGQYT--CTPYNAHGTQGSS 582 Query: 385 GKLTVTSDDDRPPPIITNGPSNQ-TLPIKSMAVFPCTA---ICTPEPIIAWYF-EGEALI 439 G + V R PP+ T P + C A T +P + W +GE L Sbjct: 583 GYMEVLV---RNPPVFTVEPQPMYQRKVGETVEMHCAAQESSGTQKPTVTWQRKDGEELA 639 Query: 440 QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485 + + V G L +++L + D G Y CV S+ V S L+V+ Sbjct: 640 RGRAKVV--GGNLTIENLKQQDFGVYECVVSNEVATIVKSTHLIVE 683 Score = 87.4 bits (207), Expect = 2e-15 Identities = 79/306 (25%), Positives = 126/306 (41%), Gaps = 15/306 (4%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 LNC+A G+P+P I WYK V + +I+ G LR + + D G Y C A N Sbjct: 330 LNCQAEGTPTPEILWYKDANPVEPSSTVTIINDG--TELRISTIKT-EDIGDYTCLARNG 386 Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL- 149 G S A + +A + P+++ +G+ VV C V W + G + Sbjct: 387 EGQI-SHTARVIIAG-GAVITIPPQNETKLEGENVVFPCEAKALPGNVTVSWYREGAPIS 444 Query: 150 -LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208 + + D+R + G+L I D+G Y C N G ++A A L + + P Sbjct: 445 EVSELDTRASVRMDGSLAINPVSADDSGTYLCTVSNGIGEPQTASAYLNVEYPAKVTFNP 504 Query: 209 EDVVAQTGSSVTFQCRV-GGDPLPDVLWRRSAG-GGNMPLGRVKVLDDGSLRLDNVILAD 266 + QC + PL V W + + + V+ +GSL V Sbjct: 505 TVQYLPFRMAGVVQCYIKANPPLQYVTWTKDKRLLEPYQVKDIVVMGNGSLLFTRVNENH 564 Query: 267 EGEYSCEAENSVGAVSASGYLTVY--DPPSINLSPNSV-NVESGNVARFTCTA---TGRP 320 G+Y+C N+ G +SGY+ V +PP + P + + G C A +G Sbjct: 565 HGQYTCTPYNAHGTQGSSGYMEVLVRNPPVFTVEPQPMYQRKVGETVEMHCAAQESSGTQ 624 Query: 321 EPTMFW 326 +PT+ W Sbjct: 625 KPTVTW 630 Score = 63.3 bits (147), Expect = 4e-08 Identities = 58/237 (24%), Positives = 98/237 (41%), Gaps = 15/237 (6%) Query: 60 ILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESK- 117 ++ G L F R H G Y C N++GT S + + V V F +EP+ Sbjct: 549 VMGNGSLLFTRVNENH-H---GQYTCTPYNAHGTQGS-SGYMEVLVRNPPVFTVEPQPMY 603 Query: 118 QSAQGDTVVLECLPPR--GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175 Q G+TV + C G+ +P V W++ L G ++ V GGNL I++ +Q D Sbjct: 604 QRKVGETVEMHCAAQESSGTQKPTVTWQRKDGEELARGRAK---VVGGNLTIENLKQQDF 660 Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP---LPD 232 G Y+C+ N T + + +P+ V Q ++++Q G P Sbjct: 661 GVYECVVSNEVATIVKSTHLIVEGTQPHAPHNVTGVADQFSVTLSWQPGYSGGPDYKQDY 720 Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289 +W R G V ++ + + E+ +N++G +SG +TV Sbjct: 721 TIWHREEGAQEWKTIPVTPSGSTTVTISRLKSGTNHEFQVVGKNALGDGMSSGIITV 777 >UniRef50_Q4T1M4 Cluster: Chromosome undetermined SCAF10538, whole genome shotgun sequence; n=9; Euteleostomi|Rep: Chromosome undetermined SCAF10538, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 2293 Score = 98.7 bits (235), Expect = 8e-19 Identities = 90/326 (27%), Positives = 131/326 (40%), Gaps = 21/326 (6%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI----LPAGGLF 67 P I+ + V ++P L C G+P P W V+ D+H + G + Sbjct: 450 PKILSSFSEKVVNPNEPVFLVCNVKGTPPPRCSWSLDDDPVIKDSHHHLGHYESHEGHVV 509 Query: 68 F-LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126 L TH +V D G Y C NS G + A ++V R R A D V Sbjct: 510 SQLNVTHTQVQ-DGGQYRCTCGNSAGVVHHQ-ARINVRG-RASVRAMKNLTAIAGRDAFV 566 Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186 C G P ++ W KN L F+ R + G L + + +Q DAG Y C Sbjct: 567 -HCRVI-GYPYYSIKWYKNSALLPFNHRQRA-FENNGTLKLSNVQQVDAGEYTCKVMVQP 623 Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQT-GSSVTFQCRV-GGDPLPDVLWRRSAGGGNM 244 +S +++ + PY+ P + T G V C V GD D+ W++ G + Sbjct: 624 NKMDSQSVHVRVRVPPYI--QPFEFQRFTIGQRVFIPCVVMSGDRPLDITWQKD--GRPI 679 Query: 245 PLGRVKVLDD----GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300 P G +D+ SLR++N+ G Y+C A N AV L V PP + P Sbjct: 680 PAGLGVTVDNIDFTSSLRINNLTPDHNGNYTCIARNEAAAVEHQSRLIVRVPPQFVVQPE 739 Query: 301 SVNVESGNVARFTCTATGRPEPTMFW 326 + G C+A G P PT+ W Sbjct: 740 DQDGIYGKTVTLNCSAEGYPPPTIVW 765 Score = 97.1 bits (231), Expect = 3e-18 Identities = 111/472 (23%), Positives = 178/472 (37%), Gaps = 42/472 (8%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 L C+A G P+P RW K + D+ R GL A G D+G Y CE NS Sbjct: 287 LPCKASGYPAPKYRWLKDNSPLEPDS-RFRQTVTGLLIESAQPG----DSGTYVCEVWNS 341 Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150 YG A L+ + P + + G V L C GS E + W +NG+ ++ Sbjct: 342 YGNAEVVGRLYVKQPLKAV--VSPRKVKGSVGSKVSLSC-SVSGSDEYELSWYRNGE-II 397 Query: 151 FDGDS-RMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209 + G+S R ++ NL+++ ++D G YQC AR + + + + P +++ Sbjct: 398 YPGNSVRFTGLNRENLIMEGMSKSDGGAYQCFARKGKMSAQDFVQVILEDGTPKILSSFS 457 Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGGGNMPLGRVKVLDD---GSLRLDNV 262 + V V C V G P P W + LG + + L + + Sbjct: 458 EKVVNPNEPVFLVCNVKGTPPPRCSWSLDDDPVIKDSHHHLGHYESHEGHVVSQLNVTHT 517 Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEP 322 + D G+Y C NS G V + V S+ N + +G A C G P Sbjct: 518 QVQDGGQYRCTCGNSAGVVHHQARINVRGRASVRAMKNLTAI-AGRDAFVHCRVIGYPYY 576 Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV---NYAG 379 ++ W + + P R + F+ L +++ + D+ C + N Sbjct: 577 SIKWY---KNSALLPFNHRQR-----AFENNGTLKLSNVQQVDA-GEYTCKVMVQPNKMD 627 Query: 380 SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGEAL 438 S V ++ R PP I Q I PC + P+ I W +G + Sbjct: 628 SQSVHVRV-------RVPPYI-QPFEFQRFTIGQRVFIPCVVMSGDRPLDITWQKDGRPI 679 Query: 439 IQNHRRNVTN---DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487 V N +L + +L +G YTC+A + L+V P Sbjct: 680 PAGLGVTVDNIDFTSSLRINNLTPDHNGNYTCIARNEAAAVEHQSRLIVRVP 731 Score = 95.1 bits (226), Expect = 1e-17 Identities = 132/535 (24%), Positives = 207/535 (38%), Gaps = 46/535 (8%) Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRLEP------ESKQSAQGDTVVLECLPPRGSP 136 Y C + Y T +R + ++ + EP E ++ V L C G P Sbjct: 238 YRCTTRHRY-TGETRQSNSARLIVSDPTNAEPAILDGFERREVMISHRVELPC-KASGYP 295 Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196 P W K+ L + DSR G L+I+ A+ D+G Y C N+ G E + L Sbjct: 296 APKYRWLKDNSPL--EPDSRFRQTVTG-LLIESAQPGDSGTYVCEVWNSYGNAE-VVGRL 351 Query: 197 KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDD 254 + + P V GS V+ C V G ++ W R+ G P V+ L+ Sbjct: 352 YVKQPLKAVVSPRKVKGSVGSKVSLSCSVSGSDEYELSWYRN-GEIIYPGNSVRFTGLNR 410 Query: 255 GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---DPPSINLSPNSVNVESGNVAR 311 +L ++ + +D G Y C A G +SA ++ V P I LS S V + N Sbjct: 411 ENLIMEGMSKSDGGAYQCFARK--GKMSAQDFVQVILEDGTPKI-LSSFSEKVVNPNEPV 467 Query: 312 F-TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG-----VTVLTINDTDKND 365 F C G P P WS++ + I +D +H ++ V+ L + T D Sbjct: 468 FLVCNVKGTPPPRCSWSLDDDPVI------KDSHHHLGHYESHEGHVVSQLNVTHTQVQD 521 Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425 C+ N AG + ++ V N T A C I P Sbjct: 522 G-GQYRCTCGNSAGVVHHQARINVRGRAS------VRAMKNLTAIAGRDAFVHCRVIGYP 574 Query: 426 EPIIAWYFEGEALIQNHR-RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 I WY L NHR R N+GTL L ++ + D+G YTC + K + S ++ V Sbjct: 575 YYSIKWYKNSALLPFNHRQRAFENNGTLKLSNVQQVDAGEYTCKVMVQPNK-MDSQSVHV 633 Query: 485 DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE--V 542 + P I F ++ P D + ++W ++ + + LG V+ Sbjct: 634 RVRVPPYIQPFEFQRF-TIGQRVFIPCVVMSGDRPLDITWQKDGRPIPAG-LGVTVDNID 691 Query: 543 FSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSG 597 F+ N TP ++ + IAR LI + F+V+ E+ G+ G Sbjct: 692 FTSSLRINNLTPDHNGNYTCIARNEAAAVEHQSRLIVRVPPQFVVQPEDQDGIYG 746 Score = 77.0 bits (181), Expect = 3e-12 Identities = 57/222 (25%), Positives = 93/222 (41%), Gaps = 7/222 (3%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 ++T + A ++CR G P +I+WYK L+ + + G L D Sbjct: 555 NLTAIAGRDAFVHCRVIGYPYYSIKWYKNSALLPFNHRQRAFENNGTLKLSNVQ---QVD 611 Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139 AG Y C+ S++ +HV V + E ++ G V + C+ G + Sbjct: 612 AGEYTCKVMVQPNKMDSQS--VHVRVRVPPYIQPFEFQRFTIGQRVFIPCVVMSGDRPLD 669 Query: 140 VYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198 + W+K+G+ + + +D +L I + G Y CIARN A E + L + Sbjct: 670 ITWQKDGRPIPAGLGVTVDNIDFTSSLRINNLTPDHNGNYTCIARNEAAAVEHQ-SRLIV 728 Query: 199 HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 + P + PED G +VT C G P P ++W S G Sbjct: 729 RVPPQFVVQPEDQDGIYGKTVTLNCSAEGYPPPTIVWEHSKG 770 Score = 63.3 bits (147), Expect = 4e-08 Identities = 94/415 (22%), Positives = 154/415 (37%), Gaps = 37/415 (8%) Query: 30 TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89 +L+C GS + WY+ G ++ S+ G G SD G Y C A Sbjct: 375 SLSCSVSGSDEYELSWYRNGEIIYPG--NSVRFTGLNRENLIMEGMSKSDGGAYQCFARK 432 Query: 90 SYGTARSRNATLHVAVLREEFR---LEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146 +A+ V V+ E+ L S++ + V +G+P P W + Sbjct: 433 GKMSAQD-----FVQVILEDGTPKILSSFSEKVVNPNEPVFLVCNVKGTPPPRCSWSLDD 487 Query: 147 QTLLFDGDSRMHLVDG--GNLVIQ----DARQTDAGRYQCIARNAAGTRESAIATLKIHI 200 ++ D + + G++V Q + D G+Y+C N+AG A + + Sbjct: 488 DPVIKDSHHHLGHYESHEGHVVSQLNVTHTQVQDGGQYRCTCGNSAGVVHHQ-ARINVRG 546 Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLD-DGSLR 258 + + +++ A G CRV G P + W +++ +P R + + +G+L+ Sbjct: 547 RA-SVRAMKNLTAIAGRDAFVHCRVIGYPYYSIKWYKNS--ALLPFNHRQRAFENNGTLK 603 Query: 259 LDNVILADEGEYSCEAENSVGAV-SASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317 L NV D GEY+C+ + S S ++ V PP I G C Sbjct: 604 LSNVQQVDAGEYTCKVMVQPNKMDSQSVHVRVRVPPYIQ-PFEFQRFTIGQRVFIPCVVM 662 Query: 318 GRPEP-TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376 P + W +G G++ D D + L IN+ D C A N Sbjct: 663 SGDRPLDITWQKDGRPIPAGLGVTVDN------IDFTSSLRINNLTP-DHNGNYTCIARN 715 Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431 A + + +L V R PP P +Q C+A P P I W Sbjct: 716 EAAAVEHQSRLIV-----RVPPQFVVQPEDQDGIYGKTVTLNCSAEGYPPPTIVW 765 Score = 62.9 bits (146), Expect = 5e-08 Identities = 79/336 (23%), Positives = 124/336 (36%), Gaps = 33/336 (9%) Query: 156 RMHLVDGGNLVIQDARQTDA-GRYQCIARN--AAGTRESAIATLKI----HIKPYLITGP 208 R + G L I D D Y+C R+ TR+S A L + + +P ++ G Sbjct: 215 RYLITSAGALYILDVLPEDGLNNYRCTTRHRYTGETRQSNSARLIVSDPTNAEPAILDGF 274 Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268 E V C+ G P P W + P R + G L +++ D G Sbjct: 275 ERREVMISHRVELPCKASGYPAPKYRWLKD-NSPLEPDSRFRQTVTGLL-IESAQPGDSG 332 Query: 269 EYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328 Y CE NS G G L V P +SP V G+ +C+ +G E + W Sbjct: 333 TYVCEVWNSYGNAEVVGRLYVKQPLKAVVSPRKVKGSVGSKVSLSCSVSGSDEYELSWYR 392 Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVT--VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386 G II+PG S F G+ L + K+D C A G + Sbjct: 393 NGE--IIYPGNS-------VRFTGLNRENLIMEGMSKSDG-GAYQCFA--RKGKMSAQDF 440 Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNV 446 + V +D P I + S + + C TP P +W + + +I++ ++ Sbjct: 441 VQVILEDGTPK--ILSSFSEKVVNPNEPVFLVCNVKGTPPPRCSWSLDDDPVIKDSHHHL 498 Query: 447 ----TNDGTLV----LKDLDKSDSGTYTCVASSRHG 474 +++G +V + D G Y C + G Sbjct: 499 GHYESHEGHVVSQLNVTHTQVQDGGQYRCTCGNSAG 534 Score = 61.7 bits (143), Expect = 1e-07 Identities = 134/601 (22%), Positives = 229/601 (38%), Gaps = 55/601 (9%) Query: 239 AGGGNMPLGRVKVLDDGSLRLDNVILAD-EGEYSCEAENSVGAVSASGYLTVYDPPSINL 297 AGG R +L +GSL + +V+ D E Y C+ N VGA + ++ S+ L Sbjct: 810 AGGMTASAARALLLSNGSLLIKHVLEDDSESMYLCKVSNDVGADAQQVHVAHRQELSM-L 868 Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMF-WSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356 + +V R C P + W + P +R T L Sbjct: 869 GGGARVGPLADVLRSCCWWRRNPSYCLRRWLTPATGYLRLPEANRLTGGCLP-----TSL 923 Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416 I T + DS C A+N G +LTV D PP + ++T+ ++ Sbjct: 924 QIMPTVREDS-GFFSCHAINSFGEDRGIIQLTVQEPPD-PPEVEIREVKDRTIALRWTMG 981 Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRH 473 F + T I L ++V+ N T++ DL S + VA + Sbjct: 982 FDGNSPITGYDIECKNKSASWLSAQVTKDVSPQLNQATII--DLHPSSTYNIRMVAKNVI 1039 Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSS 533 G NP+ D ++ GPP + S+ +SW + + Sbjct: 1040 GNS------------NPSNELTITTDEAAPDGPPLDVTLEPTSPQSIKVSWKVRPRPQGT 1087 Query: 534 SILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSH 593 + G + + L ++ + V+ R +Q Y + PG ++ F + + ++ Sbjct: 1088 CLKGRRALILP---LLLQPPLKHLQNGVI---RGYQVGY--REYSPGGSHQFTIVSVDTP 1139 Query: 594 G-------LSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDS 646 G L G + V +N G + E + D+++ + ++ + S Sbjct: 1140 GDTTESLTLDGLKKFTQYSVVVQAANRAGTGPWSPKTLEDVPSRTPDNVLAVAKSPEVIS 1199 Query: 647 KT-IKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVS-GFEITSLRKYTKYE 704 + + L E+LN L IY+ L + E+ I + V E+ L KYT Y Sbjct: 1200 VSWMPLPREVLNVNLLGYRVIYWANLP----DGELGEIRNVTAVQPSLELDGLEKYTNYR 1255 Query: 705 FFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGII 764 ++ F +G S +T +DVP GPP ++ +++ V + W PP L+L NGII Sbjct: 1256 IQVLAFTSAGDGVRSEQIYVRTKEDVP-GPPAGVKAAASSSSAVFVSWLPP-LKL-NGII 1312 Query: 765 TGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQK 824 Y + + L P S + H + NL Y++ + A T G G S+K Sbjct: 1313 RKYIIFCSDLH-PMVMSEFEASPDAH---FYRIPNLAGNRQYTIWVVAVTAAGHGNNSEK 1368 Query: 825 V 825 + Sbjct: 1369 I 1369 Score = 61.3 bits (142), Expect = 2e-07 Identities = 71/247 (28%), Positives = 103/247 (41%), Gaps = 38/247 (15%) Query: 369 TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT-NGPSNQTLPIKSMAVFPCTAICTPEP 427 TI AV AG K+TV P I+T NG T P V PC A+ P P Sbjct: 1351 TIWVVAVTAAGHGNNSEKITVEPLAKAPARILTFNG--TVTTPWMKDIVLPCKAVGDPPP 1408 Query: 428 IIAWYFEGEA------LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481 + W +G A ++ + RR V +G+ ++ + DSG Y+CVA + W G Sbjct: 1409 TVKW-IKGSANGTPTNVLVDGRRTVHANGSFFIRTVKAEDSGNYSCVAGN-----TWGG- 1461 Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541 I N+ V P P +T T TS+TLSW + G SSI GY ++ Sbjct: 1462 ----DEITLNL------QVQVPPDQPRLTVT-KTTTTSITLSWIPGDN-GGSSIRGYILQ 1509 Query: 542 VFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPV 601 +S + NS W + Y +++L G Y F + +N G S + Sbjct: 1510 -YSED---------NSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNVVGPGRISEI 1559 Query: 602 SDSVTVG 608 ++ T G Sbjct: 1560 IEAKTHG 1566 Score = 50.4 bits (115), Expect = 3e-04 Identities = 40/150 (26%), Positives = 70/150 (46%), Gaps = 10/150 (6%) Query: 13 YIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTH--RSILPAGGL--- 66 Y + L +V A ++ C AGG+ ++RWY + D R + P G L Sbjct: 19 YFVNASLQEVVFASTTGTSVPCPAGGAAPASLRWYLATGEEIYDVPGIRHVHPNGTLQIF 78 Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126 FL +++ ++ D Y+C A N G RS++ + AV RE + + +++ +G V Sbjct: 79 NFLPSSYSKLIHD-NTYYCTAENPSGKIRSQDVHIK-AVSREPYTVRVADQKAMRGSVAV 136 Query: 127 LECLPPRGSPE--PNVYWKKNGQTLLFDGD 154 +C+ P V W+K+ +L +GD Sbjct: 137 FKCIIPASVEAYIAVVSWEKDTVSLSSEGD 166 Score = 48.8 bits (111), Expect = 9e-04 Identities = 35/133 (26%), Positives = 61/133 (45%), Gaps = 6/133 (4%) Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753 + L+K+T+Y + + G S +TL+DVP P N+ + + + W Sbjct: 1148 LDGLKKFTQYSVVVQAANRAGTGPWS----PKTLEDVPSRTPDNVLAVAKSPEVISVSWM 1203 Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAE 813 P ++ N + GY V+ W ++P + N T Q SL + L +Y +Q+ A Sbjct: 1204 PLPREVLNVNLLGYRVIY-WANLPDGELGEIRNVTAVQ-PSLELDGLEKYTNYRIQVLAF 1261 Query: 814 TIIGLGPFSQKVY 826 T G G S+++Y Sbjct: 1262 TSAGDGVRSEQIY 1274 Score = 45.6 bits (103), Expect = 0.008 Identities = 36/135 (26%), Positives = 51/135 (37%), Gaps = 3/135 (2%) Query: 356 LTINDTDKNDSRNTIVCSAVN-YAGSSFVRGKLT-VTSDDDRPPPIITNGPSNQTLPIKS 413 L I D D N C+ + Y G + + SD P I +G + + I Sbjct: 224 LYILDVLPEDGLNNYRCTTRHRYTGETRQSNSARLIVSDPTNAEPAILDGFERREVMISH 283 Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473 PC A P P W + L + R T G L+++ DSGTY C + + Sbjct: 284 RVELPCKASGYPAPKYRWLKDNSPLEPDSRFRQTVTG-LLIESAQPGDSGTYVCEVWNSY 342 Query: 474 GKYVWSGALLVDSPI 488 G G L V P+ Sbjct: 343 GNAEVVGRLYVKQPL 357 Score = 44.8 bits (101), Expect = 0.015 Identities = 36/141 (25%), Positives = 58/141 (41%), Gaps = 25/141 (17%) Query: 718 PSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS-----------------------P 754 PSN T + PDGPP+++ + + ++ + W P Sbjct: 1044 PSNELTITTDEAAPDGPPLDVTLEPTSPQSIKVSWKVRPRPQGTCLKGRRALILPLLLQP 1103 Query: 755 PELQLQNGIITGYNVVVNWLDVPANK--SMVAINTTVHQATSLIMTNLTSGVSYSVQIAA 812 P LQNG+I GY V + ++V+++T SL + L YSV + A Sbjct: 1104 PLKHLQNGVIRGYQVGYREYSPGGSHQFTIVSVDTPGDTTESLTLDGLKKFTQYSVVVQA 1163 Query: 813 ETIIGLGPFSQKVYFNIDSRS 833 G GP+S K ++ SR+ Sbjct: 1164 ANRAGTGPWSPKTLEDVPSRT 1184 Score = 41.5 bits (93), Expect = 0.14 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 4/79 (5%) Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGN----MPLGRVKVLDDGSLRLDNVILADEGEYSCEA 274 + C+ GDP P V W + + G + GR V +GS + V D G YSC A Sbjct: 1396 IVLPCKAVGDPPPTVKWIKGSANGTPTNVLVDGRRTVHANGSFFIRTVKAEDSGNYSCVA 1455 Query: 275 ENSVGAVSASGYLTVYDPP 293 N+ G + L V PP Sbjct: 1456 GNTWGGDEITLNLQVQVPP 1474 Score = 40.7 bits (91), Expect = 0.24 Identities = 26/77 (33%), Positives = 37/77 (48%), Gaps = 9/77 (11%) Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGG-----VLVVSDTHRSILPAGGLFFLRATHGR 75 VT + L C+A G P P ++W KG V+ D R++ A G FF+R Sbjct: 1388 VTTPWMKDIVLPCKAVGDPPPTVKWIKGSANGTPTNVLVDGRRTV-HANGSFFIRTVKA- 1445 Query: 76 VHSDAGVYWCEATNSYG 92 D+G Y C A N++G Sbjct: 1446 --EDSGNYSCVAGNTWG 1460 Score = 39.1 bits (87), Expect = 0.72 Identities = 27/83 (32%), Positives = 39/83 (46%), Gaps = 9/83 (10%) Query: 125 VVLECLPPRGSPEPNVYWKK---NGQ--TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179 +VL C G P P V W K NG +L DG +H G+ I+ + D+G Y Sbjct: 1396 IVLPCKAV-GDPPPTVKWIKGSANGTPTNVLVDGRRTVHA--NGSFFIRTVKAEDSGNYS 1452 Query: 180 CIARNAAGTRESAIATLKIHIKP 202 C+A N G E + L++ + P Sbjct: 1453 CVAGNTWGGDEITL-NLQVQVPP 1474 >UniRef50_Q4RHM4 Cluster: Chromosome 19 SCAF15045, whole genome shotgun sequence; n=2; Tetraodon nigroviridis|Rep: Chromosome 19 SCAF15045, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1193 Score = 98.7 bits (235), Expect = 8e-19 Identities = 81/242 (33%), Positives = 113/242 (46%), Gaps = 19/242 (7%) Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ--SAQGDTVVLECLPPRGS 135 +D+G+Y C A N +G + NA L V F L P KQ A+ VV+EC PR + Sbjct: 435 ADSGMYQCVAENYWG-IKYANAELRVIAFAPTFELNPVKKQLLGARDRRVVIEC-KPRAA 492 Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195 P P W K G+ LLF+ +SR+ ++ G+L I A + D G Y C+A N G R ++ Sbjct: 493 PRPQFTWTK-GKELLFN-NSRLSILYDGSLEILSATKDDEGVYTCLAENGRG-RANSSGY 549 Query: 196 LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV--LW----RRSAGGGNMPLGRV 249 L I + PED A+ G V +C DP D+ +W R Sbjct: 550 LTITEATGITVAPEDSEAKVGDEVVLRCAASFDPTLDITFIWAIDFRVIDFDSEWQHYER 609 Query: 250 KVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES- 306 DDGS L++ NV + EG Y+C A+ V + +A L V P P + VE Sbjct: 610 LWRDDGSGDLKIKNVQIWHEGRYTCTAQTVVDSDTAYADLKVVGVPG---PPGVIRVEEI 666 Query: 307 GN 308 GN Sbjct: 667 GN 668 Score = 75.4 bits (177), Expect = 9e-12 Identities = 47/173 (27%), Positives = 76/173 (43%), Gaps = 9/173 (5%) Query: 163 GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP--EDVVAQTGSSVT 220 G L D+G YQC+A N G + + I P P + ++ V Sbjct: 425 GELQFSSLTFADSGMYQCVAENYWGIKYANAELRVIAFAPTFELNPVKKQLLGARDRRVV 484 Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMPLG--RVKVLDDGSLRLDNVILADEGEYSCEAENSV 278 +C+ P P W + G + R+ +L DGSL + + DEG Y+C AEN Sbjct: 485 IECKPRAAPRPQFTWTK---GKELLFNNSRLSILYDGSLEILSATKDDEGVYTCLAENGR 541 Query: 279 GAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EPTMFWSVE 329 G ++SGYLT+ + I ++P + G+ C A+ P + T W+++ Sbjct: 542 GRANSSGYLTITEATGITVAPEDSEAKVGDEVVLRCAASFDPTLDITFIWAID 594 Score = 65.3 bits (152), Expect = 1e-08 Identities = 55/182 (30%), Positives = 83/182 (45%), Gaps = 15/182 (8%) Query: 24 ARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVY 83 AR + + C+ +P P W KG L+ +++ SIL G L L AT D GVY Sbjct: 478 ARDRRVVIECKPRAAPRPQFTWTKGKELLFNNSRLSILYDGSLEILSAT----KDDEGVY 533 Query: 84 WCEATNSYGTARSRN-ATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP-RGSPEPNVY 141 C A N G A S T+ A + PE ++ GD VVL C + + Sbjct: 534 TCLAENGRGRANSSGYLTITEAT---GITVAPEDSEAKVGDEVVLRCAASFDPTLDITFI 590 Query: 142 WKKNGQTLLFDGD----SRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196 W + + + FD + R+ DG G+L I++ + GRY C A+ + ++A A L Sbjct: 591 WAIDFRVIDFDSEWQHYERLWRDDGSGDLKIKNVQIWHEGRYTCTAQTVVDS-DTAYADL 649 Query: 197 KI 198 K+ Sbjct: 650 KV 651 Score = 52.4 bits (120), Expect = 7e-05 Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 4/114 (3%) Query: 372 CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM-AVFPCTAICTPEPIIA 430 C A NY G + +L V + P N Q L + V C P P Sbjct: 442 CVAENYWGIKYANAELRVIAF---APTFELNPVKKQLLGARDRRVVIECKPRAAPRPQFT 498 Query: 431 WYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 W E L N R ++ DG+L + K D G YTC+A + G+ SG L + Sbjct: 499 WTKGKELLFNNSRLSILYDGSLEILSATKDDEGVYTCLAENGRGRANSSGYLTI 552 Score = 38.3 bits (85), Expect = 1.3 Identities = 25/68 (36%), Positives = 34/68 (50%), Gaps = 1/68 (1%) Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTD-AGRYQCIARNAAGTR 189 P R S P + + N + L + + + GGNLVI ++ AG Y C+ARN GT Sbjct: 32 PGRLSSLPGRWRRDNWEIKLMEQPDEHYSLVGGNLVINSPKKRKHAGTYICVARNIYGTV 91 Query: 190 ESAIATLK 197 S A LK Sbjct: 92 ISKEARLK 99 >UniRef50_A7RGM1 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 551 Score = 98.7 bits (235), Expect = 8e-19 Identities = 121/485 (24%), Positives = 195/485 (40%), Gaps = 63/485 (12%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I+ V V Q AT C G P P+I W+K G+ + + + G L L Sbjct: 1 PQFIDLMQPVEVTEGQTATFECTVKGYPRPSIEWFKNGLPLKENERIASTYEGALSSLTI 60 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATL------HV---AVLREEFRLEPESKQSAQG 122 + D G Y C A NS+G A L H + + F P ++ + +G Sbjct: 61 NQCTI-DDEGNYKCVARNSFGKASCATELLTNLNGTHTHPPHFIDKHFETAP-AEVTEEG 118 Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCI 181 D V LE + G P+P+V W K+ + ++ + D LVI Q D G+Y+ I Sbjct: 119 D-VRLE-VRVGGHPKPSVQWLKDDEVIISSPHFMVSSHADVHTLVINSPNQDDIGQYKVI 176 Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241 A N G A T ++++ G P P V W + Sbjct: 177 ASNHRG---MASRTFDVNVE-------------------------GKPKPSVEWLKD-DR 207 Query: 242 GNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298 + +K+ ++ SL + +DEG Y+ + N VG+ + + + V D + + Sbjct: 208 PVLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVGSGTRTFDVKVEDTTTNDSF 267 Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358 + E GNV R + TG+P P + W+ + + D D + LTI Sbjct: 268 VPFESTEEGNV-RLSVKITGKPVPEVSWTKDEKPVHKIQNIRLDHQ------DDIYTLTI 320 Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD--DDRPPPIITNGP--SNQTLPIKSM 414 + NDS + C+ N AG S + + + ++ P G + LP+ + Sbjct: 321 REATPNDS-GSYKCTLTNDAGKSTRTFSVEIEGETKPEKGKPTEREGKPLEEEELPVSAE 379 Query: 415 AVFPCTAICT--PEPIIAWYFEGEALIQNHRRNVT-NDGT--LVLKDLDKSDSGTYTCVA 469 TA T P+P + W+ + + + +T DGT LV+K+ K D GTYT Sbjct: 380 TEVEMTAQVTGKPQPSVEWFKDDVPVSPDEHITITEEDGTYSLVIKEPTKKDEGTYTVEV 439 Query: 470 SSRHG 474 S+ G Sbjct: 440 SNEAG 444 Score = 72.9 bits (171), Expect = 5e-11 Identities = 94/378 (24%), Positives = 150/378 (39%), Gaps = 39/378 (10%) Query: 30 TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89 T + G P P++ W K V+SD+H + ++ L SD G+Y + TN Sbjct: 187 TFDVNVEGKPKPSVEWLKDDRPVLSDSHIKMTEEDDIYSLTIREP-TKSDEGMYTVKITN 245 Query: 90 SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149 G+ +R + V P +S + V L + G P P V W K+ + + Sbjct: 246 DVGSG-TRTFDVKVEDTTTNDSFVPF--ESTEEGNVRLS-VKITGKPVPEVSWTKDEKPV 301 Query: 150 LFDGDSRM-HLVDGGNLVIQDARQTDAGRYQCIARNAAG--TRESAIA----TLKIHIKP 202 + R+ H D L I++A D+G Y+C N AG TR ++ T KP Sbjct: 302 HKIQNIRLDHQDDIYTLTIREATPNDSGSYKCTLTNDAGKSTRTFSVEIEGETKPEKGKP 361 Query: 203 YLITGP----EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG--S 256 G E++ + V +V G P P V W + + +DG S Sbjct: 362 TEREGKPLEEEELPVSAETEVEMTAQVTGKPQPSVEWFKDDVPVSPDEHITITEEDGTYS 421 Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP----PSINLSPNSV---------N 303 L + DEG Y+ E N G + ++V D P + P + + Sbjct: 422 LVIKEPTKKDEGTYTVEVSNEAGLGRRTFDVSVDDTRKTIPKDAVKPKFIEDGSFVPFQS 481 Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363 + G+V R T TG+PEP + W+ +G P + D H + +LTI + Sbjct: 482 TDEGDV-RLTVKVTGKPEPEVTWTKDGKPVDKLPNVELD--HQEDRY----ILTIREASP 534 Query: 364 NDSRNTIVCSAVNYAGSS 381 +DS + C+ + G S Sbjct: 535 DDS-GSYRCTLTSDVGKS 551 Score = 62.5 bits (145), Expect = 7e-08 Identities = 94/388 (24%), Positives = 159/388 (40%), Gaps = 63/388 (16%) Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRY 178 +G T EC +G P P++ W KNG L + + +G +L I D G Y Sbjct: 14 EGQTATFECTV-KGYPRPSIEWFKNGLPLK-ENERIASTYEGALSSLTINQCTIDDEGNY 71 Query: 179 QCIARNAAGTRESAIATLK----IHIKP------YLITGPEDVVAQTGSSVTFQCRVGGD 228 +C+ARN+ G A L H P + T P +V + V + RVGG Sbjct: 72 KCVARNSFGKASCATELLTNLNGTHTHPPHFIDKHFETAPAEVTEE--GDVRLEVRVGGH 129 Query: 229 PLPDVLWRRSAGGG-NMPLGRVKV-LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY 286 P P V W + + P V D +L +++ D G+Y A N G S + Sbjct: 130 PKPSVQWLKDDEVIISSPHFMVSSHADVHTLVINSPNQDDIGQYKVIASNHRGMASRT-- 187 Query: 287 LTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHA 346 +D VNVE G+P+P++ W ++ +R ++ D + Sbjct: 188 ---FD----------VNVE------------GKPKPSVEW-LKDDRPVL-----SDSHIK 216 Query: 347 TAVFDGVTVLTINDTDKNDS-RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPS 405 D + LTI + K+D T+ + +G+ K+ T+ +D P + Sbjct: 217 MTEEDDIYSLTIREPTKSDEGMYTVKITNDVGSGTRTFDVKVEDTTTNDSFVPFESTEEG 276 Query: 406 NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL--IQNHRRNVTND-GTLVLKDLDKSDS 462 N L +K P P ++W + + + IQN R + +D TL +++ +DS Sbjct: 277 NVRLSVKITG--------KPVPEVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATPNDS 328 Query: 463 GTYTCVASSRHGKYVWSGALLVDSPINP 490 G+Y C ++ GK + ++ ++ P Sbjct: 329 GSYKCTLTNDAGKSTRTFSVEIEGETKP 356 Score = 51.2 bits (117), Expect = 2e-04 Identities = 45/181 (24%), Positives = 73/181 (40%), Gaps = 17/181 (9%) Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79 ++ V+ + + G P P++ W+K V V D H +I G + L D Sbjct: 373 ELPVSAETEVEMTAQVTGKPQPSVEWFKDDVPVSPDEHITITEEDGTYSL-VIKEPTKKD 431 Query: 80 AGVYWCEATNSYGTAR--------SRNATLHVAVLREEFRLEPES----KQSAQGDTVVL 127 G Y E +N G R T+ ++ +F +E S + + +GD V Sbjct: 432 EGTYTVEVSNEAGLGRRTFDVSVDDTRKTIPKDAVKPKF-IEDGSFVPFQSTDEGD--VR 488 Query: 128 ECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186 + G PEP V W K+G+ + H D L I++A D+G Y+C + Sbjct: 489 LTVKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDV 548 Query: 187 G 187 G Sbjct: 549 G 549 Score = 43.2 bits (97), Expect = 0.044 Identities = 46/203 (22%), Positives = 80/203 (39%), Gaps = 16/203 (7%) Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG-VTVLTIND 360 V V G A F CT G P P++ W G P ++ +T ++G ++ LTIN Sbjct: 10 VEVTEGQTATFECTVKGYPRPSIEWFKNG-----LPLKENERIAST--YEGALSSLTINQ 62 Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKL--TVTSDDDRPPPIITNGPSNQTLPI--KSMAV 416 +D N C A N G + +L + PP I + + Sbjct: 63 CTIDDEGN-YKCVARNSFGKASCATELLTNLNGTHTHPPHFIDKHFETAPAEVTEEGDVR 121 Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRH 473 P+P + W + E +I + V++ TLV+ ++ D G Y +AS+ Sbjct: 122 LEVRVGGHPKPSVQWLKDDEVIISSPHFMVSSHADVHTLVINSPNQDDIGQYKVIASNHR 181 Query: 474 GKYVWSGALLVDSPINPNIHFFR 496 G + + V+ P++ + + Sbjct: 182 GMASRTFDVNVEGKPKPSVEWLK 204 >UniRef50_Q4RVM1 Cluster: Chromosome 9 SCAF14991, whole genome shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 9 SCAF14991, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1197 Score = 97.9 bits (233), Expect = 1e-18 Identities = 84/321 (26%), Positives = 133/321 (41%), Gaps = 31/321 (9%) Query: 6 VTSGEAP-YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64 + G P ++ P D + + C G PS I W K G L + D + Sbjct: 251 MVEGAPPEWLTGPPQDQLLVIGSDVHIKCSVSGKPSSDIIWRKNGELFIDDPENNRRVLD 310 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEF--------RLEPES 116 L H D VY C+A+N +G A +++ V+ E R+ Sbjct: 311 DTVVL---HNAGPEDTAVYQCDASNGHGGLL---ANINIMVMSESQGSLLDMTPRILTSD 364 Query: 117 KQS---AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT 173 Q QG V++ C SP P + W + G+ R + G+L I A + Sbjct: 365 SQEYPVVQGVDVIMNC-SAFSSPLPTISWFRGANQEAVKGE-RFFTLQNGSLQIIGAEKN 422 Query: 174 DAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP-LPD 232 D+G+Y C+A N G + + A L + +++GP D +G++ C+ D L D Sbjct: 423 DSGKYVCVALNTEG-KAAVTAVLDVKDPTRIVSGPRDAEVMSGATAQLICQAEYDKSLQD 481 Query: 233 ---VLWRRSAGGGNMPLGRVK----VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASG 285 ++WR+ G ++PL + + D LR+ NV L D G Y C A S+ ++A+ Sbjct: 482 SFVLVWRKD--GDDIPLSVEENSRYAVADSMLRIMNVALNDSGTYMCIARTSLDEMNATA 539 Query: 286 YLTVYDPPSINLSPNSVNVES 306 LTV D P L + S Sbjct: 540 LLTVLDVPDAPLKVEISEIRS 560 Score = 95.5 bits (227), Expect = 8e-18 Identities = 100/389 (25%), Positives = 159/389 (40%), Gaps = 40/389 (10%) Query: 162 GGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG-PEDVVAQTGSSVT 220 G L++ + ++D G+Y C A+N+AG + P +TG P+D + GS V Sbjct: 217 GRLLILSEVEESDGGQYMCKAKNSAGEAVHYFNVMVEGAPPEWLTGPPQDQLLVIGSDVH 276 Query: 221 FQCRVGGDPLPDVLWRRSAG-GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279 +C V G P D++WR++ + P +VLDD ++ L N D Y C+A N G Sbjct: 277 IKCSVSGKPSSDIIWRKNGELFIDDPENNRRVLDD-TVVLHNAGPEDTAVYQCDASNGHG 335 Query: 280 AVSAS----------GYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVE 329 + A+ G L P + V G C+A P PT+ W Sbjct: 336 GLLANINIMVMSESQGSLLDMTPRILTSDSQEYPVVQGVDVIMNCSAFSSPLPTISW--- 392 Query: 330 GNRTIIFPGMSRDKYHATAVFDGVT-VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT 388 F G +++ F L I +KNDS VC A+N G + V L Sbjct: 393 ------FRGANQEAVKGERFFTLQNGSLQIIGAEKNDS-GKYVCVALNTEGKAAVTAVL- 444 Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA----ICTPEPIIAWYFEGEAL---IQN 441 D + P I +GP + + + A C A ++ W +G+ + ++ Sbjct: 445 ----DVKDPTRIVSGPRDAEVMSGATAQLICQAEYDKSLQDSFVLVWRKDGDDIPLSVEE 500 Query: 442 HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV----DSPINPNIHFFRA 497 + R D L + ++ +DSGTY C+A + + + L V D+P+ I R+ Sbjct: 501 NSRYAVADSMLRIMNVALNDSGTYMCIARTSLDEMNATALLTVLDVPDAPLKVEISEIRS 560 Query: 498 ADVSSLPGPPTKPITHNVTDTSVTLSWSQ 526 SL P +VT+ V SQ Sbjct: 561 PRNISLSWVPGSDHNSSVTEFVVEFQESQ 589 Score = 95.5 bits (227), Expect = 8e-18 Identities = 88/332 (26%), Positives = 136/332 (40%), Gaps = 22/332 (6%) Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137 SD G Y C+A NS G A + E P+ + G V ++C G P Sbjct: 228 SDGGQYMCKAKNSAGEAVHYFNVMVEGAPPEWLTGPPQDQLLVIGSDVHIKC-SVSGKPS 286 Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197 ++ W+KNG+ + D ++ ++D +V+ +A D YQC A N G + I + Sbjct: 287 SDIIWRKNGELFIDDPENNRRVLDD-TVVLHNAGPEDTAVYQCDASNGHGGLLANINIMV 345 Query: 198 --------IHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248 + + P ++T ++ G V C PLP + W R A + R Sbjct: 346 MSESQGSLLDMTPRILTSDSQEYPVVQGVDVIMNCSAFSSPLPTISWFRGANQEAVKGER 405 Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGN 308 L +GSL++ D G+Y C A N+ G + + L V DP I P V SG Sbjct: 406 FFTLQNGSLQIIGAEKNDSGKYVCVALNTEGKAAVTAVLDVKDPTRIVSGPRDAEVMSGA 465 Query: 309 VARFTCTA----TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364 A+ C A + + + W +G+ P +S ++ AV D ++L I + N Sbjct: 466 TAQLICQAEYDKSLQDSFVLVWRKDGDD---IP-LSVEENSRYAVAD--SMLRIMNVALN 519 Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP 396 DS T +C A LTV D P Sbjct: 520 DS-GTYMCIARTSLDEMNATALLTVLDVPDAP 550 Score = 62.1 bits (144), Expect = 9e-08 Identities = 53/180 (29%), Positives = 73/180 (40%), Gaps = 12/180 (6%) Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD--THRSILPA 63 +TS +I P D TV + C A G+P P RW K G V T Sbjct: 7 ITSYSPGRVIALPFDKTVK------IECDARGNPPPQYRWTKDGEDFVPPRATTTKTQHT 60 Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123 G F L + + G Y C A N GTA ++ TL V + + ++ +GD Sbjct: 61 DGSFVLH--NKQFIQFQGTYRCYAFNKLGTAMTKEITLIVPTVPKFPKVGEPPIAVDEGD 118 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAG-RYQCIA 182 + L C PP G+ +YW L+ D R+ + GNL A Q D+ Y C A Sbjct: 119 PITLHCHPPEGAVPRQLYWMSLDLQLI-QQDERVSMGTDGNLYFSHALQNDSRLDYYCNA 177 Score = 41.1 bits (92), Expect = 0.18 Identities = 39/156 (25%), Positives = 62/156 (39%), Gaps = 6/156 (3%) Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDG--DSRMHLVDGGNLVIQDARQTDAGRYQCI 181 TV +EC RG+P P W K+G+ + ++ DG ++ G Y+C Sbjct: 23 TVKIEC-DARGNPPPQYRWTKDGEDFVPPRATTTKTQHTDGSFVLHNKQFIQFQGTYRCY 81 Query: 182 ARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240 A N GT + TL + P + G + G +T C +P L+ S Sbjct: 82 AFNKLGTAMTKEITLIVPTVPKFPKVGEPPIAVDEGDPITLHCHPPEGAVPRQLYWMSLD 141 Query: 241 GGNMPLG-RVKVLDDGSLRLDNVILADEG-EYSCEA 274 + RV + DG+L + + D +Y C A Sbjct: 142 LQLIQQDERVSMGTDGNLYFSHALQNDSRLDYYCNA 177 >UniRef50_Q9BWV1 Cluster: Brother of CDO precursor; n=27; Euteleostomi|Rep: Brother of CDO precursor - Homo sapiens (Human) Length = 1114 Score = 97.9 bits (233), Expect = 1e-18 Identities = 96/375 (25%), Positives = 148/375 (39%), Gaps = 28/375 (7%) Query: 112 LEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR 171 ++P S G TV+L C+ P NV W+ NG+ L D+ L+ G LVI Sbjct: 40 VQPASTVQKPGGTVILGCVVE--PPRMNVTWRLNGKELNGSDDALGVLITHGTLVITALN 97 Query: 172 QTDAGRYQCIARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRV-GGDP 229 GRYQC+AR AG S AT+ + +++ + + + G++ C + P Sbjct: 98 NHTVGRYQCVARMPAGAVASVPATVTLANLQDFKLDVQHVIEVDEGNTAVIACHLPESHP 157 Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSV-GAVSASG--- 285 V + G ++ G+L++ N DEG Y C A N V V SG Sbjct: 158 KAQVRYSVKQEWLEASRGNYLIMPSGNLQIVNASQEDEGMYKCAAYNPVTQEVKTSGSSD 217 Query: 286 ----YLTVYDPPSINLSP--NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGM 339 + + I P ++ V G C A+G P P + W+ +G+ Sbjct: 218 RLRVRRSTAEAARIIYPPEAQTIIVTKGQSLILECVASGIPPPRVTWAKDGS-------- 269 Query: 340 SRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPI 399 S Y+ T ++ L I+ T + DS T C A N G + + + PP Sbjct: 270 SVTGYNKTRFL--LSNLLIDTTSEEDS-GTYRCMADNGVGQP--GAAVILYNVQVFEPPE 324 Query: 400 ITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDK 459 +T S +P A C P P + W LI + R ++ VL + Sbjct: 325 VTMELSQLVIPWGQSAKLTCEVRGNPPPSVLWLRNAVPLISSQRLRLSRRALRVL-SMGP 383 Query: 460 SDSGTYTCVASSRHG 474 D G Y C+A + G Sbjct: 384 EDEGVYQCMAENEVG 398 Score = 87.4 bits (207), Expect = 2e-15 Identities = 82/280 (29%), Positives = 126/280 (45%), Gaps = 32/280 (11%) Query: 21 VTVARHQPATLNCRAGGS-PSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS 78 + V A + C S P +R+ K L S + I+P+G L + A+ Sbjct: 138 IEVDEGNTAVIACHLPESHPKAQVRYSVKQEWLEASRGNYLIMPSGNLQIVNASQ----E 193 Query: 79 DAGVYWCEATN----------SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128 D G+Y C A N S R R +T A R + E ++ +G +++LE Sbjct: 194 DEGMYKCAAYNPVTQEVKTSGSSDRLRVRRSTAEAA--RIIYPPEAQTIIVTKGQSLILE 251 Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188 C+ G P P V W K+G ++ +R L NL+I + D+G Y+C+A N G Sbjct: 252 CVAS-GIPPPRVTWAKDGSSVTGYNKTRFLL---SNLLIDTTSEEDSGTYRCMADNGVGQ 307 Query: 189 RESAIATLKIHI--KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246 +A+ + + P + +V G S C V G+P P VLW R+A +PL Sbjct: 308 PGAAVILYNVQVFEPPEVTMELSQLVIPWGQSAKLTCEVRGNPPPSVLWLRNA----VPL 363 Query: 247 ---GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSA 283 R++ L +LR+ ++ DEG Y C AEN VG+ A Sbjct: 364 ISSQRLR-LSRRALRVLSMGPEDEGVYQCMAENEVGSAHA 402 Score = 59.7 bits (138), Expect = 5e-07 Identities = 52/190 (27%), Positives = 75/190 (39%), Gaps = 12/190 (6%) Query: 7 TSGEAPYIIEQP--LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64 ++ EA II P + V + Q L C A G P P + W K G V L + Sbjct: 224 STAEAARIIYPPEAQTIIVTKGQSLILECVASGIPPPRVTWAKDGSSVTGYNKTRFLLSN 283 Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR-EEFRLEPESKQSAQGD 123 L + D+G Y C A N G + +V V E +E G Sbjct: 284 LLIDTTS-----EEDSGTYRCMADNGVGQPGAAVILYNVQVFEPPEVTMELSQLVIPWGQ 338 Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183 + L C RG+P P+V W +N L+ R+ L V+ + D G YQC+A Sbjct: 339 SAKLTC-EVRGNPPPSVLWLRNAVPLI--SSQRLRLSRRALRVLSMGPE-DEGVYQCMAE 394 Query: 184 NAAGTRESAI 193 N G+ + + Sbjct: 395 NEVGSAHAVV 404 >UniRef50_Q4SCU0 Cluster: Chromosome 7 SCAF14650, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 7 SCAF14650, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 265 Score = 97.5 bits (232), Expect = 2e-18 Identities = 50/109 (45%), Positives = 63/109 (57%), Gaps = 6/109 (5%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-----THRSILPAGGL 66 P I+E P D+ V++ +PATLNC+A G P+P + WYK G V +D +HR +LP G L Sbjct: 20 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTVEWYKDGERVETDRDNPRSHRMLLPTGSL 79 Query: 67 FFLRATHG-RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP 114 FFLR HG R D G Y C A N G A S NA+L VA + P Sbjct: 80 FFLRIVHGRRSKPDDGSYVCVARNYLGQAISHNASLEVATFPRQVFFSP 128 Score = 42.7 bits (96), Expect = 0.059 Identities = 37/127 (29%), Positives = 54/127 (42%), Gaps = 18/127 (14%) Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGGGNMPLGRVKVLDDGSL 257 P ++ P D++ G T C+ G P P V W R + P +L GSL Sbjct: 20 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTVEWYKDGERVETDRDNPRSHRMLLPTGSL 79 Query: 258 RLDNVI-----LADEGEYSCEAENSVG-AVSASGYL-------TVYDPPSINLSPNSVNV 304 ++ D+G Y C A N +G A+S + L V+ PS+ +SP S + Sbjct: 80 FFLRIVHGRRSKPDDGSYVCVARNYLGQAISHNASLEVATFPRQVFFSPSVEISPYSFSQ 139 Query: 305 ES-GNVA 310 S G VA Sbjct: 140 TSQGYVA 146 Score = 41.1 bits (92), Expect = 0.18 Identities = 30/91 (32%), Positives = 46/91 (50%), Gaps = 9/91 (9%) Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS-RMH--LVDGGNL----VIQDAR- 171 ++G+ L C G P P V W K+G+ + D D+ R H L+ G+L ++ R Sbjct: 32 SKGEPATLNC-KAEGRPTPTVEWYKDGERVETDRDNPRSHRMLLPTGSLFFLRIVHGRRS 90 Query: 172 QTDAGRYQCIARNAAGTRESAIATLKIHIKP 202 + D G Y C+ARN G S A+L++ P Sbjct: 91 KPDDGSYVCVARNYLGQAISHNASLEVATFP 121 Score = 39.1 bits (87), Expect = 0.72 Identities = 22/57 (38%), Positives = 27/57 (47%), Gaps = 1/57 (1%) Query: 277 SVGAVSASGYLTVYD-PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332 SV S+ L D PP I P+ + V G A C A GRP PT+ W +G R Sbjct: 3 SVPCYSSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTVEWYKDGER 59 Score = 38.7 bits (86), Expect = 0.96 Identities = 29/115 (25%), Positives = 48/115 (41%), Gaps = 10/115 (8%) Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL------IQNHRRNVTNDG 450 PP I PS+ + A C A P P + WY +GE + ++HR + Sbjct: 19 PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTVEWYKDGERVETDRDNPRSHRMLLPTGS 78 Query: 451 TLVLKDL----DKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVS 501 L+ + K D G+Y CVA + G+ + A L + + F + ++S Sbjct: 79 LFFLRIVHGRRSKPDDGSYVCVARNYLGQAISHNASLEVATFPRQVFFSPSVEIS 133 >UniRef50_Q967D7 Cluster: Protein turtle; n=5; Drosophila melanogaster|Rep: Protein turtle - Drosophila melanogaster (Fruit fly) Length = 1531 Score = 97.5 bits (232), Expect = 2e-18 Identities = 137/550 (24%), Positives = 212/550 (38%), Gaps = 59/550 (10%) Query: 78 SDAGVYWCEATN-SYGTARSRNAT-LHVAV-LREEFRLEPESKQSAQ-GDTVVLECLPPR 133 SD G Y C+ + + +N T H+ V F + PE GD+++L C Sbjct: 220 SDQGWYECKVVFLNRDPKQHKNGTWFHLDVHAPPRFSVTPEDIIYVNLGDSIILNCQAD- 278 Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192 G+P P + W K+ + D + + DG L I R D G Y CIARN G + S Sbjct: 279 GTPTPEILWYKDANPV--DPSPTVGIFNDGTELRISTIRHEDIGEYTCIARNGEG-QVSH 335 Query: 193 IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP-LPDVLWRRSAGGGNMPLG---R 248 A + I ++ P + G V F C P V W R R Sbjct: 336 TARVIIAGGAVIMVPPTNQTKLEGEKVIFSCEAKAMPGNVTVRWYREGSPVREVAALETR 395 Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSPNSVNVESG 307 V + DGSL ++ + D G+Y CE N +G SAS YL+V P + +P + Sbjct: 396 VTIRKDGSLIINPIKPDDSGQYLCEVTNGIGDPQSASAYLSVEYPAKVTFTPTVQYLPFR 455 Query: 308 NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT-INDTDKNDS 366 C P+ + + ++ ++ P +D + +G + T +N+ + Sbjct: 456 LAGVVQCYIKSSPQ-LQYVTWTKDKRLLEPYQMKD---IVVMANGSLLFTRVNE----EH 507 Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN-QTLPIKSMAVFPCTAI--- 422 + C+ N G++ G + V R PP T P + C A+ Sbjct: 508 QGQYACTPYNAQGTAGASGVMDVLV---RKPPAFTVEPETLYQRKVGDSVEMHCDALEAE 564 Query: 423 CTPEPIIAWYF-EGEALIQNHRRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480 T P I W EGE L ++ R + + G + +++L + D G Y CV S+ + Sbjct: 565 GTERPTIKWQRQEGEQLTESQRNRIKISGGNITIENLRREDFGYYQCVVSNEVATLMAVT 624 Query: 481 ALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQV 540 L+++ + P P IT T++S+TL W GS Y Sbjct: 625 QLVIE---------------GTQPHAPYN-ITGKATESSITLQWLPGYSGGSEYKQDY-- 666 Query: 541 EVFSRETLSGNNTPRNSRGWVVIA-RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599 ++ RE +G N W I+ T + L G TY F V N G S Sbjct: 667 TIWFRE--AGVN------DWQTISVTPSGSTQVTINGLASGTTYEFQVVGRNVLGDGMMS 718 Query: 600 PVSDSVTVGD 609 V T+ D Sbjct: 719 KVMTVRTLED 728 Score = 89.0 bits (211), Expect = 7e-16 Identities = 81/330 (24%), Positives = 138/330 (41%), Gaps = 23/330 (6%) Query: 164 NLVIQDARQTDAGRYQC----IARNAAGTRESAIATLKIHIKPYLITGPEDVV-AQTGSS 218 +L + + R++D G Y+C + R+ + L +H P PED++ G S Sbjct: 211 SLNLTNIRESDQGWYECKVVFLNRDPKQHKNGTWFHLDVHAPPRFSVTPEDIIYVNLGDS 270 Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENS 277 + C+ G P P++LW + A + P V + +DG+ LR+ + D GEY+C A N Sbjct: 271 IILNCQADGTPTPEILWYKDANPVD-PSPTVGIFNDGTELRISTIRHEDIGEYTCIARNG 329 Query: 278 VGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP-EPTMFWSVEGNRTIIF 336 G VS + + + I + P + G F+C A P T+ W EG+ Sbjct: 330 EGQVSHTARVIIAGGAVIMVPPTNQTKLEGEKVIFSCEAKAMPGNVTVRWYREGSPVREV 389 Query: 337 PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGS-SFVRGKLTVTSDDDR 395 + + T DG L IN +DS +C N G L+V Sbjct: 390 AAL---ETRVTIRKDG--SLIINPIKPDDS-GQYLCEVTNGIGDPQSASAYLSV-----E 438 Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN---VTNDGTL 452 P +T P+ Q LP + V C +P+ + + + L++ ++ V +G+L Sbjct: 439 YPAKVTFTPTVQYLPFRLAGVVQCYIKSSPQLQYVTWTKDKRLLEPYQMKDIVVMANGSL 498 Query: 453 VLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482 + +++ G Y C + G SG + Sbjct: 499 LFTRVNEEHQGQYACTPYNAQGTAGASGVM 528 Score = 88.2 bits (209), Expect = 1e-15 Identities = 80/306 (26%), Positives = 126/306 (41%), Gaps = 15/306 (4%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 LNC+A G+P+P I WYK V I G LR + R H D G Y C A N Sbjct: 273 LNCQADGTPTPEILWYKDANPVDPSPTVGIFNDG--TELRISTIR-HEDIGEYTCIARNG 329 Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL- 149 G S A + +A + P ++ +G+ V+ C V W + G + Sbjct: 330 EGQV-SHTARVIIAG-GAVIMVPPTNQTKLEGEKVIFSCEAKAMPGNVTVRWYREGSPVR 387 Query: 150 -LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208 + ++R+ + G+L+I + D+G+Y C N G +SA A L + + P Sbjct: 388 EVAALETRVTIRKDGSLIINPIKPDDSGQYLCEVTNGIGDPQSASAYLSVEYPAKVTFTP 447 Query: 209 EDVVAQTGSSVTFQCRVGGDP-LPDVLWRRSAG-GGNMPLGRVKVLDDGSLRLDNVILAD 266 + QC + P L V W + + + V+ +GSL V Sbjct: 448 TVQYLPFRLAGVVQCYIKSSPQLQYVTWTKDKRLLEPYQMKDIVVMANGSLLFTRVNEEH 507 Query: 267 EGEYSCEAENSVGAVSASGYLTVY--DPPSINLSPNSV-NVESGNVARFTC---TATGRP 320 +G+Y+C N+ G ASG + V PP+ + P ++ + G+ C A G Sbjct: 508 QGQYACTPYNAQGTAGASGVMDVLVRKPPAFTVEPETLYQRKVGDSVEMHCDALEAEGTE 567 Query: 321 EPTMFW 326 PT+ W Sbjct: 568 RPTIKW 573 Score = 65.3 bits (152), Expect = 1e-08 Identities = 67/256 (26%), Positives = 102/256 (39%), Gaps = 24/256 (9%) Query: 60 ILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESK- 117 ++ G L F R G Y C N+ GTA + + + V V + F +EPE+ Sbjct: 492 VMANGSLLFTRVNE----EHQGQYACTPYNAQGTAGA-SGVMDVLVRKPPAFTVEPETLY 546 Query: 118 QSAQGDTVVLEC--LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175 Q GD+V + C L G+ P + W++ L + + GGN+ I++ R+ D Sbjct: 547 QRKVGDSVEMHCDALEAEGTERPTIKWQRQEGEQLTESQRNRIKISGGNITIENLRREDF 606 Query: 176 GRYQCIARNAAGTRESAIATLKIH----IKPYLITGPEDVVAQTGSSVTFQC---RVGGD 228 G YQC+ N T A+ L I PY ITG T SS+T Q GG Sbjct: 607 GYYQCVVSNEVATL-MAVTQLVIEGTQPHAPYNITG-----KATESSITLQWLPGYSGGS 660 Query: 229 PLPD--VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY 286 +W R AG + V + ++ + E+ N +G S Sbjct: 661 EYKQDYTIWFREAGVNDWQTISVTPSGSTQVTINGLASGTTYEFQVVGRNVLGDGMMSKV 720 Query: 287 LTVYDPPSINLSPNSV 302 +TV +P +V Sbjct: 721 MTVRTLEDAPAAPRNV 736 >UniRef50_A7RNL2 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 267 Score = 97.1 bits (231), Expect = 3e-18 Identities = 75/261 (28%), Positives = 116/261 (44%), Gaps = 20/261 (7%) Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90 L C G P P I K GV ++ + A H AG Y C+AT++ Sbjct: 19 LECIVYGMPVPKITLRKKGVHMILGQVTGNARRHYIPKFTANH------AGKYKCKATDT 72 Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150 G + + + + E+ P+ + L C G+P W NGQ L+ Sbjct: 73 SGRTDTSTTIVRMEA-KPEWITRPQDTIAGVNSNTTLRC-HASGAPRVFYQWYCNGQPLV 130 Query: 151 FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE- 209 S+ H++ G+L++++ R +D G YQC+ N G IA+ ++ + PE Sbjct: 131 ---TSQRHILHQGDLILKELRYSDGGMYQCVVTNTHG---QLIASAELTVAG--TRAPEA 182 Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNVILADEG 268 A S+VT C+ G+P P V WR+ G + G R + L G L++ NV D G Sbjct: 183 SKNALVDSTVTLHCQPSGNPKPMVRWRK--GSVYLSSGPRYQFLTSGDLKISNVTSLDSG 240 Query: 269 EYSCEAENSVGAVSASGYLTV 289 Y+CE N +G+ S +G L V Sbjct: 241 RYTCEVSNRLGSASRTGRLNV 261 Score = 85.0 bits (201), Expect = 1e-14 Identities = 59/214 (27%), Positives = 100/214 (46%), Gaps = 16/214 (7%) Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFD---GDSRMHLVDGGNLVIQDARQ 172 +K + +G+ VLEC+ G P P + +K G ++ G++R H I Sbjct: 8 TKIALKGERFVLECIV-YGMPVPKITLRKKGVHMILGQVTGNARRHY-------IPKFTA 59 Query: 173 TDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232 AG+Y+C A + +G +++ +++ KP IT P+D +A S+ T +C G P Sbjct: 60 NHAGKYKCKATDTSGRTDTSTTIVRMEAKPEWITRPQDTIAGVNSNTTLRCHASG--APR 117 Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292 V ++ G + + +L G L L + +D G Y C N+ G + AS LTV Sbjct: 118 VFYQWYCNGQPLVTSQRHILHQGDLILKELRYSDGGMYQCVVTNTHGQLIASAELTVAGT 177 Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326 + S N++ V+S C +G P+P + W Sbjct: 178 RAPEASKNAL-VDS--TVTLHCQPSGNPKPMVRW 208 Score = 82.2 bits (194), Expect = 8e-14 Identities = 61/178 (34%), Positives = 85/178 (47%), Gaps = 15/178 (8%) Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71 P I +P D + TL C A G+P +WY G +V+ + R IL G L Sbjct: 89 PEWITRPQDTIAGVNSNTTLRCHASGAPRVFYQWYCNGQPLVT-SQRHILHQGDLILKEL 147 Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD-TVVLECL 130 +SD G+Y C TN++G + +A L VA R PE+ ++A D TV L C Sbjct: 148 R----YSDGGMYQCVVTNTHGQLIA-SAELTVAGTR-----APEASKNALVDSTVTLHC- 196 Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188 P G+P+P V W+K G L G R + G+L I + D+GRY C N G+ Sbjct: 197 QPSGNPKPMVRWRK-GSVYLSSG-PRYQFLTSGDLKISNVTSLDSGRYTCEVSNRLGS 252 Score = 55.2 bits (127), Expect = 1e-05 Identities = 29/88 (32%), Positives = 44/88 (50%), Gaps = 2/88 (2%) Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKD 456 P IT P + + S C A P WY G+ L+ + +R++ + G L+LK+ Sbjct: 89 PEWITR-PQDTIAGVNSNTTLRCHASGAPRVFYQWYCNGQPLVTS-QRHILHQGDLILKE 146 Query: 457 LDKSDSGTYTCVASSRHGKYVWSGALLV 484 L SD G Y CV ++ HG+ + S L V Sbjct: 147 LRYSDGGMYQCVVTNTHGQLIASAELTV 174 Score = 49.6 bits (113), Expect = 5e-04 Identities = 28/74 (37%), Positives = 38/74 (51%), Gaps = 5/74 (6%) Query: 30 TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89 TL+C+ G+P P +RW KG V + S L +G L T D+G Y CE +N Sbjct: 193 TLHCQPSGNPKPMVRWRKGSVYLSSGPRYQFLTSGDLKISNVT----SLDSGRYTCEVSN 248 Query: 90 SYGTARSRNATLHV 103 G+A SR L+V Sbjct: 249 RLGSA-SRTGRLNV 261 Score = 48.4 bits (110), Expect = 0.001 Identities = 63/277 (22%), Positives = 97/277 (35%), Gaps = 29/277 (10%) Query: 212 VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLR---LDNVILADEG 268 +A G +C V G P+P + R+ G +M LG+V G+ R + G Sbjct: 10 IALKGERFVLECIVYGMPVPKITLRKK--GVHMILGQVT----GNARRHYIPKFTANHAG 63 Query: 269 EYSCEAENSVGAVSASGYLTVYDP-PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327 +Y C+A ++ G S + + P P + C A+G P W Sbjct: 64 KYKCKATDTSGRTDTSTTIVRMEAKPEWITRPQDTIAGVNSNTTLRCHASGAPRVFYQWY 123 Query: 328 VEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387 G + + H D L + + +D C N G +L Sbjct: 124 CNGQPLVT------SQRHILHQGD----LILKELRYSDG-GMYQCVVTNTHGQLIASAEL 172 Query: 388 TVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT 447 TV R P N + T+ + C P+P++ W L R Sbjct: 173 TVAGT--RAPEASKNALVDSTVTLH------CQPSGNPKPMVRWRKGSVYLSSGPRYQFL 224 Query: 448 NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484 G L + ++ DSG YTC S+R G +G L V Sbjct: 225 TSGDLKISNVTSLDSGRYTCEVSNRLGSASRTGRLNV 261 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.315 0.132 0.393 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 1,441,545,397 Number of Sequences: 1657284 Number of extensions: 65956432 Number of successful extensions: 195383 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 710 Number of HSP's successfully gapped in prelim test: 928 Number of HSP's that attempted gapping in prelim test: 166959 Number of HSP's gapped (non-prelim): 15182 length of query: 1207 length of database: 575,637,011 effective HSP length: 109 effective length of query: 1098 effective length of database: 394,993,055 effective search space: 433702374390 effective search space used: 433702374390 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.6 bits) S2: 78 (35.5 bits)
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