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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000888-TA|BGIBMGA000888-PA|IPR003599|Immunoglobulin
subtype, IPR003598|Immunoglobulin subtype 2, IPR003961|Fibronectin,
type III, IPR013098|Immunoglobulin I-set, IPR013151|Immunoglobulin,
IPR007110|Immunoglobulin-like, IPR008957|Fibronectin, type III-like
fold
         (1207 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q174G3 Cluster: Roundabout; n=5; Aedes aegypti|Rep: Rou...   932   0.0  
UniRef50_UPI0000D56E5C Cluster: PREDICTED: similar to CG5423-PA;...   925   0.0  
UniRef50_Q9GPP6 Cluster: Roundabout 3; n=4; Diptera|Rep: Roundab...   880   0.0  
UniRef50_Q9VQ08 Cluster: CG5481-PA; n=6; Diptera|Rep: CG5481-PA ...   722   0.0  
UniRef50_UPI0000D55AA5 Cluster: PREDICTED: similar to CG13521-PA...   675   0.0  
UniRef50_Q9W213 Cluster: CG13521-PB, isoform B; n=5; Sophophora|...   634   e-180
UniRef50_Q17BD3 Cluster: Roundabout 1; n=3; Culicidae|Rep: Round...   617   e-175
UniRef50_Q17BD5 Cluster: Roundabout; n=1; Aedes aegypti|Rep: Rou...   598   e-169
UniRef50_UPI0000DB7FD0 Cluster: PREDICTED: similar to roundabout...   580   e-163
UniRef50_Q98SW3 Cluster: Transmembrane receptor Roundabout3; n=2...   528   e-148
UniRef50_Q9HCK4 Cluster: Roundabout homolog 2 precursor; n=45; E...   508   e-142
UniRef50_O44928 Cluster: SAX-3; n=3; Caenorhabditis|Rep: SAX-3 -...   506   e-141
UniRef50_Q9Y6N7 Cluster: Roundabout homolog 1 precursor; n=74; C...   500   e-139
UniRef50_Q4RRT1 Cluster: Chromosome 16 SCAF15002, whole genome s...   444   e-123
UniRef50_Q96MS0 Cluster: Roundabout homolog 3 precursor; n=23; E...   436   e-120
UniRef50_UPI0000E4900E Cluster: PREDICTED: similar to transmembr...   429   e-118
UniRef50_UPI0000E46659 Cluster: PREDICTED: similar to roundabout...   412   e-113
UniRef50_UPI0000ECA411 Cluster: UPI0000ECA411 related cluster; n...   341   7e-92
UniRef50_A1XCJ3 Cluster: RoboA; n=1; Schmidtea mediterranea|Rep:...   281   8e-74
UniRef50_UPI0000EBE6C5 Cluster: PREDICTED: hypothetical protein;...   280   1e-73
UniRef50_Q172F7 Cluster: Roundabout, putative; n=2; Culicidae|Re...   268   6e-70
UniRef50_UPI00006A0174 Cluster: Roundabout homolog 4 precursor (...   237   1e-60
UniRef50_Q71B05 Cluster: Roundabout-like protein 4; n=5; Danio r...   227   2e-57
UniRef50_Q4SCT9 Cluster: Chromosome 7 SCAF14650, whole genome sh...   219   3e-55
UniRef50_UPI000065EA6D Cluster: Homolog of Brachydanio rerio "Ro...   219   5e-55
UniRef50_Q96RW7 Cluster: Hemicentin-1 precursor; n=40; Eumetazoa...   206   4e-51
UniRef50_Q4RJ20 Cluster: Chromosome 1 SCAF15039, whole genome sh...   204   9e-51
UniRef50_Q4SL83 Cluster: Chromosome 7 SCAF14557, whole genome sh...   203   2e-50
UniRef50_Q92626 Cluster: Peroxidasin homolog; n=49; Eumetazoa|Re...   201   8e-50
UniRef50_Q4SR23 Cluster: Chromosome 11 SCAF14528, whole genome s...   187   1e-45
UniRef50_Q4S2G3 Cluster: Chromosome undetermined SCAF14761, whol...   186   2e-45
UniRef50_UPI0000E460A7 Cluster: PREDICTED: similar to OTTHUMP000...   182   7e-44
UniRef50_P97798 Cluster: Neogenin precursor; n=37; Euteleostomi|...   177   1e-42
UniRef50_UPI0000D9D2C3 Cluster: PREDICTED: similar to peroxidasi...   177   2e-42
UniRef50_A7S5L2 Cluster: Predicted protein; n=1; Nematostella ve...   175   5e-42
UniRef50_UPI0000F2BDAE Cluster: PREDICTED: similar to hCG1996527...   174   1e-41
UniRef50_UPI0000DA21B5 Cluster: PREDICTED: similar to hemicentin...   170   2e-40
UniRef50_Q4S8U5 Cluster: Chromosome 7 SCAF14703, whole genome sh...   170   2e-40
UniRef50_UPI00004DA303 Cluster: UPI00004DA303 related cluster; n...   170   2e-40
UniRef50_Q02246 Cluster: Contactin-2 precursor; n=38; Euteleosto...   169   3e-40
UniRef50_UPI0000F34A69 Cluster: UPI0000F34A69 related cluster; n...   168   7e-40
UniRef50_Q92859 Cluster: Neogenin precursor; n=34; Euteleostomi|...   168   7e-40
UniRef50_O94779 Cluster: Contactin-5 precursor; n=52; Euteleosto...   167   2e-39
UniRef50_UPI0000F2B6E2 Cluster: PREDICTED: hypothetical protein;...   166   3e-39
UniRef50_UPI00004D4C52 Cluster: Roundabout homolog 4 precursor (...   166   3e-39
UniRef50_Q7Z5N4 Cluster: Protein sidekick-1 precursor; n=62; Eut...   165   6e-39
UniRef50_Q8TD84 Cluster: Down syndrome cell adhesion molecule-li...   164   1e-38
UniRef50_UPI0000DB7011 Cluster: PREDICTED: similar to CG33519-PB...   164   1e-38
UniRef50_A2CEC7 Cluster: Novel protein similar to Down syndrome ...   163   2e-38
UniRef50_Q8NDA2 Cluster: Hemicentin-2; n=28; Euteleostomi|Rep: H...   163   3e-38
UniRef50_Q5XNV8 Cluster: Neogenin/DCC long isoform; n=5; Vertebr...   162   5e-38
UniRef50_Q4RYE5 Cluster: Chromosome 2 SCAF14976, whole genome sh...   162   5e-38
UniRef50_Q8IVU1 Cluster: Putative neuronal cell adhesion molecul...   162   5e-38
UniRef50_Q9UQ52 Cluster: Contactin-6 precursor; n=78; Euteleosto...   162   5e-38
UniRef50_O76518 Cluster: Hemicentin precursor; n=4; Eukaryota|Re...   161   1e-37
UniRef50_UPI00005BDC8C Cluster: PREDICTED: similar to hemicentin...   161   1e-37
UniRef50_UPI0000F1ECB4 Cluster: PREDICTED: similar to hemicentin...   160   2e-37
UniRef50_Q9VS29 Cluster: CG32387-PA, isoform A; n=15; Endopteryg...   160   2e-37
UniRef50_UPI000065D4F5 Cluster: Homolog of Danio rerio "Novel he...   159   4e-37
UniRef50_UPI0000E48C89 Cluster: PREDICTED: similar to Nr-CAM pro...   159   6e-37
UniRef50_Q12860 Cluster: Contactin-1 precursor; n=31; Euteleosto...   159   6e-37
UniRef50_UPI0000D57997 Cluster: PREDICTED: similar to CG33519-PB...   157   2e-36
UniRef50_Q2VWP7 Cluster: Protogenin homolog; n=32; Euteleostomi|...   157   2e-36
UniRef50_Q6WRI0 Cluster: Immunoglobulin superfamily member 10 pr...   156   4e-36
UniRef50_Q49AK4 Cluster: DCC protein; n=9; Euteleostomi|Rep: DCC...   155   7e-36
UniRef50_UPI0000E47894 Cluster: PREDICTED: similar to scavenger ...   155   9e-36
UniRef50_UPI0000D8E943 Cluster: Down syndrome cell adhesion mole...   155   9e-36
UniRef50_A6BM71 Cluster: Connectin; n=8; Gallus gallus|Rep: Conn...   155   9e-36
UniRef50_P20241 Cluster: Neuroglian precursor; n=17; Endopterygo...   154   1e-35
UniRef50_Q0E9K8 Cluster: CG17800-PAN; n=84; Endopterygota|Rep: C...   153   3e-35
UniRef50_A5X6X5 Cluster: Titin a; n=10; Euteleostomi|Rep: Titin ...   152   5e-35
UniRef50_UPI0000D576E1 Cluster: PREDICTED: similar to CG12002-PA...   151   9e-35
UniRef50_Q4RJ21 Cluster: Chromosome 1 SCAF15039, whole genome sh...   151   1e-34
UniRef50_A7SM31 Cluster: Predicted protein; n=1; Nematostella ve...   151   1e-34
UniRef50_UPI000155CDCD Cluster: PREDICTED: similar to adlican; n...   151   1e-34
UniRef50_Q0E8G9 Cluster: CG33274-PB; n=9; Endopterygota|Rep: CG3...   149   3e-34
UniRef50_Q58EX2 Cluster: Protein sidekick-2 precursor; n=19; Eut...   148   8e-34
UniRef50_UPI0000E80BF7 Cluster: PREDICTED: similar to bone speci...   148   1e-33
UniRef50_UPI0000D56997 Cluster: PREDICTED: similar to CG8581-PA,...   147   1e-33
UniRef50_Q59E65 Cluster: CG33519-PB; n=5; Sophophora|Rep: CG3351...   147   1e-33
UniRef50_Q8WZ75 Cluster: Roundabout homolog 4 precursor; n=22; T...   146   2e-33
UniRef50_Q9NR99 Cluster: Matrix-remodeling-associated protein 5 ...   146   2e-33
UniRef50_Q4S6A5 Cluster: Chromosome 9 SCAF14729, whole genome sh...   146   3e-33
UniRef50_O18465 Cluster: Tractin; n=7; Coelomata|Rep: Tractin - ...   146   3e-33
UniRef50_O01761 Cluster: Muscle M-line assembly protein unc-89; ...   146   3e-33
UniRef50_Q13308 Cluster: Tyrosine-protein kinase-like 7 precurso...   146   3e-33
UniRef50_O00533 Cluster: Neural cell adhesion molecule L1-like p...   146   3e-33
UniRef50_Q4SR20 Cluster: Chromosome 11 SCAF14528, whole genome s...   145   6e-33
UniRef50_Q98902 Cluster: Neural cell adhesion molecule L1 precur...   145   6e-33
UniRef50_UPI0000E4A6A5 Cluster: PREDICTED: similar to heparan su...   145   7e-33
UniRef50_Q4T8B2 Cluster: Chromosome undetermined SCAF7849, whole...   145   7e-33
UniRef50_UPI0000F2E6F1 Cluster: PREDICTED: similar to L1 cell ad...   144   1e-32
UniRef50_UPI0000F1EDBC Cluster: PREDICTED: similar to adlican; n...   144   2e-32
UniRef50_Q4RVM2 Cluster: Chromosome 9 SCAF14991, whole genome sh...   144   2e-32
UniRef50_A4JYE0 Cluster: CDNA, clone cssl:d0205; n=2; Danio reri...   144   2e-32
UniRef50_P32004 Cluster: Neural cell adhesion molecule L1 precur...   143   2e-32
UniRef50_UPI0000E815E6 Cluster: PREDICTED: similar to roundabout...   143   3e-32
UniRef50_P98160 Cluster: Basement membrane-specific heparan sulf...   143   3e-32
UniRef50_UPI0000E46295 Cluster: PREDICTED: similar to Down syndr...   142   4e-32
UniRef50_Q4RE92 Cluster: Chromosome undetermined SCAF15134, whol...   142   5e-32
UniRef50_Q8WZ42 Cluster: Titin; n=65; Eukaryota|Rep: Titin - Hom...   141   9e-32
UniRef50_Q4SHH6 Cluster: Chromosome 5 SCAF14581, whole genome sh...   141   1e-31
UniRef50_UPI00004D93F2 Cluster: immunoglobulin superfamily, memb...   140   2e-31
UniRef50_UPI0000DB6D93 Cluster: PREDICTED: similar to CG32387-PB...   138   6e-31
UniRef50_O97394 Cluster: Protein sidekick precursor; n=9; Endopt...   138   9e-31
UniRef50_UPI0000E47478 Cluster: PREDICTED: similar to hemicentin...   138   1e-30
UniRef50_Q8C310-3 Cluster: Isoform 3 of Q8C310 ; n=2; Murinae|Re...   138   1e-30
UniRef50_UPI0000F33D9D Cluster: Perlecan; n=1; Bos taurus|Rep: P...   137   2e-30
UniRef50_Q4RVM0 Cluster: Chromosome 9 SCAF14991, whole genome sh...   136   3e-30
UniRef50_A2AT18 Cluster: Titin; n=11; Eukaryota|Rep: Titin - Mus...   136   3e-30
UniRef50_Q4RY92 Cluster: Chromosome 3 SCAF14978, whole genome sh...   136   5e-30
UniRef50_UPI0000DB6C79 Cluster: PREDICTED: similar to PTK7 prote...   134   2e-29
UniRef50_Q4S2G4 Cluster: Chromosome undetermined SCAF14761, whol...   134   2e-29
UniRef50_O94856 Cluster: Neurofascin precursor; n=64; Euteleosto...   133   2e-29
UniRef50_Q4SR22 Cluster: Chromosome 11 SCAF14528, whole genome s...   133   3e-29
UniRef50_UPI0000DB7802 Cluster: PREDICTED: similar to Neogenin p...   132   4e-29
UniRef50_Q4TAD5 Cluster: Chromosome undetermined SCAF7373, whole...   132   4e-29
UniRef50_Q7QEI6 Cluster: ENSANGP00000020451; n=1; Anopheles gamb...   132   6e-29
UniRef50_Q810U4 Cluster: Neuronal cell adhesion molecule precurs...   132   6e-29
UniRef50_UPI00006607E8 Cluster: Homolog of Homo sapiens "OTTHUMP...   132   7e-29
UniRef50_UPI000065FAD3 Cluster: Homolog of Brachydanio rerio "Ne...   131   1e-28
UniRef50_Q92823 Cluster: Neuronal cell adhesion molecule precurs...   131   1e-28
UniRef50_Q08CM9 Cluster: Zgc:152904; n=12; Euteleostomi|Rep: Zgc...   130   2e-28
UniRef50_Q03696 Cluster: Neuronal-glial cell adhesion molecule p...   130   2e-28
UniRef50_Q1JUB3 Cluster: L1-like cell adhesion molecule; n=1; Du...   130   2e-28
UniRef50_UPI0000E4747A Cluster: PREDICTED: similar to neuroglian...   129   4e-28
UniRef50_Q4RZE9 Cluster: Chromosome undetermined SCAF14935, whol...   129   4e-28
UniRef50_UPI000065D5B9 Cluster: Contactin-4 precursor (Brain-der...   128   7e-28
UniRef50_UPI0000E4A418 Cluster: PREDICTED: similar to axonin-1; ...   128   1e-27
UniRef50_UPI0000D5796D Cluster: PREDICTED: similar to CG31190-PA...   127   2e-27
UniRef50_Q4SIF9 Cluster: Chromosome 5 SCAF14581, whole genome sh...   126   4e-27
UniRef50_Q8TDY8 Cluster: Neighbor of punc e11 precursor; n=23; T...   126   4e-27
UniRef50_UPI00015B613E Cluster: PREDICTED: similar to frazzled p...   125   6e-27
UniRef50_Q9VN14 Cluster: Contactin precursor; n=4; Endopterygota...   125   6e-27
UniRef50_UPI0000519A30 Cluster: PREDICTED: similar to Peroxidasi...   124   1e-26
UniRef50_UPI0000D560FB Cluster: PREDICTED: similar to CG1084-PA;...   124   2e-26
UniRef50_UPI0000D55944 Cluster: PREDICTED: similar to CG8967-PA;...   123   3e-26
UniRef50_A7RGL7 Cluster: Predicted protein; n=1; Nematostella ve...   123   3e-26
UniRef50_UPI00006A0696 Cluster: DDM36; n=4; Tetrapoda|Rep: DDM36...   123   3e-26
UniRef50_Q4SI43 Cluster: Chromosome 5 SCAF14581, whole genome sh...   123   3e-26
UniRef50_UPI0000ECA0F8 Cluster: Neurofascin precursor.; n=3; Gal...   122   5e-26
UniRef50_Q59FX6 Cluster: Protein tyrosine phosphatase, receptor ...   122   6e-26
UniRef50_Q4RVZ3 Cluster: Chromosome 9 SCAF14991, whole genome sh...   122   8e-26
UniRef50_P13591 Cluster: Neural cell adhesion molecule 1, 140 kD...   122   8e-26
UniRef50_UPI0000DB6DF8 Cluster: PREDICTED: similar to leucine-ri...   121   1e-25
UniRef50_UPI00015B6341 Cluster: PREDICTED: similar to KLG; n=1; ...   120   2e-25
UniRef50_Q23991 Cluster: Peroxidasin precursor; n=7; Coelomata|R...   120   2e-25
UniRef50_A7RGM2 Cluster: Predicted protein; n=1; Nematostella ve...   120   2e-25
UniRef50_O15394 Cluster: Neural cell adhesion molecule 2 precurs...   120   2e-25
UniRef50_Q90478 Cluster: Neural cell adhesion molecule L1.1; n=9...   120   2e-25
UniRef50_UPI0000ECD748 Cluster: UPI0000ECD748 related cluster; n...   120   3e-25
UniRef50_A7S4D5 Cluster: Predicted protein; n=1; Nematostella ve...   118   7e-25
UniRef50_UPI00015B5045 Cluster: PREDICTED: similar to receptor t...   118   1e-24
UniRef50_Q4SPP8 Cluster: Chromosome 16 SCAF14537, whole genome s...   118   1e-24
UniRef50_Q94155 Cluster: Unc-40 protein; n=2; Caenorhabditis|Rep...   118   1e-24
UniRef50_A7RNP0 Cluster: Predicted protein; n=2; Nematostella ve...   117   2e-24
UniRef50_UPI00015A4156 Cluster: Neogenin precursor.; n=1; Danio ...   117   2e-24
UniRef50_Q4RRR9 Cluster: Chromosome 16 SCAF15002, whole genome s...   117   2e-24
UniRef50_Q8NFA8 Cluster: Transmembrane receptor PTK7-2; n=18; Eu...   117   2e-24
UniRef50_Q4KMQ7 Cluster: NRCAM protein; n=10; Euteleostomi|Rep: ...   117   2e-24
UniRef50_Q4S5S6 Cluster: Chromosome 9 SCAF14729, whole genome sh...   116   4e-24
UniRef50_A7SVH4 Cluster: Predicted protein; n=2; Nematostella ve...   116   4e-24
UniRef50_UPI0000D57760 Cluster: PREDICTED: similar to leucine-ri...   116   5e-24
UniRef50_O44329 Cluster: Receptor tyrosine phosphatase; n=1; Hir...   116   5e-24
UniRef50_P16621 Cluster: Tyrosine-protein phosphatase Lar precur...   116   5e-24
UniRef50_UPI00015A60B9 Cluster: UPI00015A60B9 related cluster; n...   115   7e-24
UniRef50_Q4RHM3 Cluster: Chromosome 19 SCAF15045, whole genome s...   115   7e-24
UniRef50_UPI00015B5487 Cluster: PREDICTED: similar to leucine-ri...   115   9e-24
UniRef50_UPI00015A3FB5 Cluster: hypothetical protein LOC553690; ...   115   9e-24
UniRef50_Q7KSE9 Cluster: CG31190-PB, isoform B; n=4; Diptera|Rep...   115   9e-24
UniRef50_Q6IDE9 Cluster: LP21844p; n=2; Sophophora|Rep: LP21844p...   115   9e-24
UniRef50_UPI0000E468FC Cluster: PREDICTED: similar to KLG; n=3; ...   114   1e-23
UniRef50_A0S6W8 Cluster: Hemicentin-like protein 2; n=2; Spodopt...   114   1e-23
UniRef50_UPI0000F1ECB5 Cluster: PREDICTED: similar to novel hemi...   114   2e-23
UniRef50_A7RGL8 Cluster: Predicted protein; n=1; Nematostella ve...   113   2e-23
UniRef50_A7RGM0 Cluster: Predicted protein; n=1; Nematostella ve...   113   4e-23
UniRef50_UPI0000E46E64 Cluster: PREDICTED: similar to SAPS287; n...   112   6e-23
UniRef50_UPI0000DB72ED Cluster: PREDICTED: similar to CG33950-PD...   112   6e-23
UniRef50_Q4SPP9 Cluster: Chromosome 16 SCAF14537, whole genome s...   112   6e-23
UniRef50_A7RQE6 Cluster: Predicted protein; n=3; Nematostella ve...   112   6e-23
UniRef50_O15146 Cluster: Muscle, skeletal receptor tyrosine prot...   112   6e-23
UniRef50_Q13332 Cluster: Receptor-type tyrosine-protein phosphat...   111   8e-23
UniRef50_Q15746 Cluster: Myosin light chain kinase, smooth muscl...   111   8e-23
UniRef50_Q96JA1 Cluster: Leucine-rich repeats and immunoglobulin...   111   8e-23
UniRef50_Q4KMG0 Cluster: Cell adhesion molecule-related/down-reg...   111   8e-23
UniRef50_UPI0000546958 Cluster: PREDICTED: hypothetical protein;...   111   1e-22
UniRef50_UPI0000DB7443 Cluster: PREDICTED: similar to Fasciclin ...   111   1e-22
UniRef50_Q8WR45 Cluster: Immunoglobulin domain-containing protei...   111   1e-22
UniRef50_A7SC07 Cluster: Predicted protein; n=1; Nematostella ve...   111   1e-22
UniRef50_Q8AXY6 Cluster: Muscle, skeletal receptor tyrosine prot...   110   2e-22
UniRef50_Q9I7U4-3 Cluster: Isoform B of Q9I7U4 ; n=6; Sophophora...   110   3e-22
UniRef50_Q4TBR4 Cluster: Chromosome undetermined SCAF7099, whole...   110   3e-22
UniRef50_Q0E8J3 Cluster: CG33484-PD, isoform D; n=9; Sophophora|...   110   3e-22
UniRef50_UPI00015B41E3 Cluster: PREDICTED: similar to fasciclin ...   109   3e-22
UniRef50_UPI00015B50B3 Cluster: PREDICTED: similar to cell adhes...   109   5e-22
UniRef50_A7SVH6 Cluster: Predicted protein; n=1; Nematostella ve...   109   5e-22
UniRef50_A7SSL0 Cluster: Predicted protein; n=1; Nematostella ve...   109   5e-22
UniRef50_UPI0000E4617C Cluster: PREDICTED: similar to novel immu...   109   6e-22
UniRef50_UPI0000DB6E73 Cluster: PREDICTED: similar to CG31190-PB...   109   6e-22
UniRef50_Q4SW90 Cluster: Chromosome undetermined SCAF13667, whol...   109   6e-22
UniRef50_A1Z920 Cluster: CG8581-PA, isoform A; n=8; Diptera|Rep:...   109   6e-22
UniRef50_O94898 Cluster: Leucine-rich repeats and immunoglobulin...   109   6e-22
UniRef50_Q61YY0 Cluster: Putative uncharacterized protein CBG033...   108   8e-22
UniRef50_UPI0000D55E60 Cluster: PREDICTED: similar to CG32796-PB...   108   1e-21
UniRef50_Q17AC3 Cluster: Leucine-rich transmembrane protein; n=2...   108   1e-21
UniRef50_UPI0000DB720E Cluster: PREDICTED: similar to zormin CG3...   107   1e-21
UniRef50_Q4S1C0 Cluster: Chromosome 13 SCAF14769, whole genome s...   107   1e-21
UniRef50_A4JYL6 Cluster: Sid4; n=4; Clupeocephala|Rep: Sid4 - Da...   107   1e-21
UniRef50_UPI0000E472F4 Cluster: PREDICTED: similar to SEC14 and ...   107   2e-21
UniRef50_UPI00004D1686 Cluster: Neogenin precursor.; n=1; Xenopu...   107   2e-21
UniRef50_Q4RKK6 Cluster: Chromosome 5 SCAF15028, whole genome sh...   107   2e-21
UniRef50_Q7Q0S6 Cluster: ENSANGP00000006166; n=5; cellular organ...   107   2e-21
UniRef50_P23468 Cluster: Receptor-type tyrosine-protein phosphat...   107   2e-21
UniRef50_UPI0000F2186B Cluster: PREDICTED: hypothetical protein;...   106   3e-21
UniRef50_Q6UXM1 Cluster: Leucine-rich repeats and immunoglobulin...   106   3e-21
UniRef50_Q8UVD6 Cluster: Brother of CDO; n=2; Danio rerio|Rep: B...   106   4e-21
UniRef50_Q4RRS5 Cluster: Chromosome 16 SCAF15002, whole genome s...   106   4e-21
UniRef50_Q1ENI8 Cluster: Peroxidasin (Drosophila peroxidase) hom...   106   4e-21
UniRef50_UPI0000DB6DA9 Cluster: PREDICTED: similar to CG32387-PB...   105   6e-21
UniRef50_Q7Q3K8 Cluster: ENSANGP00000009916; n=4; Endopterygota|...   104   1e-20
UniRef50_A7TCD9 Cluster: Predicted protein; n=1; Nematostella ve...   104   1e-20
UniRef50_UPI00015B5ECA Cluster: PREDICTED: similar to rCG56583; ...   103   2e-20
UniRef50_Q7SY58 Cluster: Muscle, skeletal, receptor tyrosine kin...   103   3e-20
UniRef50_A0JM54 Cluster: LOC100036605 protein; n=1; Xenopus trop...   103   4e-20
UniRef50_Q6UXZ4 Cluster: Netrin receptor UNC5D precursor; n=44; ...   103   4e-20
UniRef50_Q6PDN3 Cluster: Myosin light chain kinase, smooth muscl...   103   4e-20
UniRef50_Q9UPX0 Cluster: Protein turtle homolog B precursor; n=2...   102   5e-20
UniRef50_UPI0000E48847 Cluster: PREDICTED: similar to titin isof...   102   7e-20
UniRef50_Q9BMN8 Cluster: Tyrosine-protein phosphatase Lar-like p...   102   7e-20
UniRef50_A7RK32 Cluster: Predicted protein; n=2; Nematostella ve...   100   2e-19
UniRef50_Q8IZJ1 Cluster: Netrin receptor UNC5B precursor; n=38; ...   100   2e-19
UniRef50_Q6UWL6 Cluster: Kin of IRRE-like protein 2 precursor; n...   100   2e-19
UniRef50_UPI0000F20186 Cluster: PREDICTED: similar to cell adhes...   100   3e-19
UniRef50_Q4S556 Cluster: Chromosome 6 SCAF14737, whole genome sh...   100   3e-19
UniRef50_UPI0000E4A8AD Cluster: PREDICTED: similar to Ptprd prot...    99   4e-19
UniRef50_UPI000065CE26 Cluster: Homolog of Homo sapiens "Hemicen...    99   4e-19
UniRef50_P34082 Cluster: Fasciclin-2 precursor; n=7; Diptera|Rep...    99   4e-19
UniRef50_Q9W4Y3 Cluster: CG33950-PF, isoform F; n=13; Coelomata|...   100   5e-19
UniRef50_UPI0000D55C03 Cluster: PREDICTED: similar to CG33484-PA...    99   6e-19
UniRef50_A7SQE0 Cluster: Predicted protein; n=1; Nematostella ve...    99   6e-19
UniRef50_Q9P2J2 Cluster: Protein turtle homolog A precursor; n=2...    99   6e-19
UniRef50_UPI00015B59DF Cluster: PREDICTED: similar to turtle pro...    99   8e-19
UniRef50_Q4T1M4 Cluster: Chromosome undetermined SCAF10538, whol...    99   8e-19
UniRef50_Q4RHM4 Cluster: Chromosome 19 SCAF15045, whole genome s...    99   8e-19
UniRef50_A7RGM1 Cluster: Predicted protein; n=1; Nematostella ve...    99   8e-19
UniRef50_Q4RVM1 Cluster: Chromosome 9 SCAF14991, whole genome sh...    98   1e-18
UniRef50_Q9BWV1 Cluster: Brother of CDO precursor; n=27; Euteleo...    98   1e-18
UniRef50_Q4SCU0 Cluster: Chromosome 7 SCAF14650, whole genome sh...    97   2e-18
UniRef50_Q967D7 Cluster: Protein turtle; n=5; Drosophila melanog...    97   2e-18
UniRef50_A7RNL2 Cluster: Predicted protein; n=1; Nematostella ve...    97   3e-18
UniRef50_Q4RQ36 Cluster: Chromosome 17 SCAF15006, whole genome s...    97   3e-18
UniRef50_Q9I7U4 Cluster: Titin; n=7; Endopterygota|Rep: Titin - ...    97   3e-18
UniRef50_Q4RRD1 Cluster: Chromosome 16 SCAF15002, whole genome s...    96   6e-18
UniRef50_P11799 Cluster: Myosin light chain kinase, smooth muscl...    96   6e-18
UniRef50_Q8NFP4 Cluster: MAM domain-containing glycosylphosphati...    96   6e-18
UniRef50_P22648 Cluster: Fasciclin-2 precursor; n=1; Schistocerc...    96   6e-18
UniRef50_UPI0000E46FA4 Cluster: PREDICTED: similar to protein ty...    95   8e-18
UniRef50_Q1L8D0 Cluster: Cell adhesion molecule-related/down-reg...    95   8e-18
UniRef50_UPI0000E4A429 Cluster: PREDICTED: similar to guanine de...    95   1e-17
UniRef50_UPI0000D56C0A Cluster: PREDICTED: similar to CG6669-PA;...    95   1e-17
UniRef50_A7S831 Cluster: Predicted protein; n=1; Nematostella ve...    95   1e-17
UniRef50_O18466 Cluster: LeechCAM; n=1; Hirudo medicinalis|Rep: ...    94   2e-17
UniRef50_A7SVH5 Cluster: Predicted protein; n=1; Nematostella ve...    94   2e-17
UniRef50_A4JYK0 Cluster: Si:dkey-24p1.1; n=3; Danio rerio|Rep: S...    94   2e-17
UniRef50_A7T084 Cluster: Predicted protein; n=1; Nematostella ve...    94   2e-17
UniRef50_A7T3W0 Cluster: Predicted protein; n=1; Nematostella ve...    93   3e-17
UniRef50_A7RT26 Cluster: Predicted protein; n=1; Nematostella ve...    93   3e-17
UniRef50_UPI0000D56EF9 Cluster: PREDICTED: similar to CG12676-PA...    93   6e-17
UniRef50_Q6R3L9 Cluster: Hemolin; n=5; Bombyx|Rep: Hemolin - Bom...    93   6e-17
UniRef50_Q6UWL6-4 Cluster: Isoform 4 of Q6UWL6 ; n=6; Catarrhini...    92   1e-16
UniRef50_A7RTW2 Cluster: Predicted protein; n=1; Nematostella ve...    91   1e-16
UniRef50_O95185 Cluster: Netrin receptor UNC5C precursor; n=54; ...    91   1e-16
UniRef50_O75147 Cluster: Obscurin-like protein 1 precursor; n=35...    91   1e-16
UniRef50_UPI0000F1EF3F Cluster: PREDICTED: hypothetical protein;...    91   2e-16
UniRef50_UPI0000E46F13 Cluster: PREDICTED: similar to CG33141-PB...    91   2e-16
UniRef50_UPI0000D9DD6E Cluster: PREDICTED: similar to hemicentin...    91   2e-16
UniRef50_Q06561 Cluster: Basement membrane proteoglycan precurso...    91   2e-16
UniRef50_Q7YT99 Cluster: Twitchin; n=4; Mollusca|Rep: Twitchin -...    91   2e-16
UniRef50_UPI000051A210 Cluster: PREDICTED: similar to CG32796-PB...    90   3e-16
UniRef50_UPI00006602C0 Cluster: Netrin receptor UNC5D precursor ...    90   3e-16
UniRef50_UPI0000ECAAF1 Cluster: Netrin receptor UNC5A precursor ...    90   3e-16
UniRef50_UPI000065E234 Cluster: Homolog of Homo sapiens "OTTHUMP...    90   4e-16
UniRef50_Q9TWA6 Cluster: APCAM=CELL adhesion molecule from CDNA ...    90   4e-16
UniRef50_Q9BIA2 Cluster: Neuronal igcam protein 6, isoform b; n=...    90   4e-16
UniRef50_A7SWF5 Cluster: Predicted protein; n=3; Nematostella ve...    90   4e-16
UniRef50_UPI0000EB292A Cluster: Leucine-rich repeats and immunog...    89   7e-16
UniRef50_Q4SJF7 Cluster: Chromosome 4 SCAF14575, whole genome sh...    89   7e-16
UniRef50_O97137 Cluster: Fasciclin II transmembrane isoform; n=3...    89   7e-16
UniRef50_Q6PF50 Cluster: MGC68902 protein; n=2; Xenopus|Rep: MGC...    89   9e-16
UniRef50_Q9VNP2 Cluster: CG8779-PA, isoform A; n=3; Drosophila m...    89   9e-16
UniRef50_Q00872 Cluster: Myosin-binding protein C, slow-type; n=...    89   9e-16
UniRef50_UPI000065D2BB Cluster: Homolog of Homo sapiens "Palladi...    88   2e-15
UniRef50_Q53U87 Cluster: SAX-7 LONGFORM; n=6; Caenorhabditis|Rep...    88   2e-15
UniRef50_Q15772 Cluster: Striated muscle preferentially expresse...    88   2e-15
UniRef50_P31398 Cluster: Hemolin precursor; n=12; Obtectomera|Re...    88   2e-15
UniRef50_UPI0000E49A7A Cluster: PREDICTED: hypothetical protein,...    87   2e-15
UniRef50_UPI0000E46930 Cluster: PREDICTED: similar to sidekick-2...    87   2e-15
UniRef50_UPI0000DB7010 Cluster: PREDICTED: similar to CG33519-PB...    87   2e-15
UniRef50_Q5W9G3 Cluster: LAR splice variant 1; n=24; Eutheria|Re...    87   2e-15
UniRef50_Q95TU8 Cluster: Netrin receptor unc-5 precursor; n=3; D...    87   2e-15
UniRef50_UPI0000519C8D Cluster: PREDICTED: similar to echinoid C...    87   3e-15
UniRef50_Q4TAJ7 Cluster: Chromosome undetermined SCAF7304, whole...    87   3e-15
UniRef50_Q11WJ9 Cluster: CHU large protein; uncharacterized; n=1...    87   3e-15
UniRef50_Q7Z553 Cluster: MAM domain-containing glycosylphosphati...    87   3e-15
UniRef50_UPI0000DB8006 Cluster: PREDICTED: similar to sallimus C...    87   4e-15
UniRef50_UPI0000E815EC Cluster: PREDICTED: hypothetical protein;...    86   5e-15
UniRef50_Q4RFN0 Cluster: Chromosome 16 SCAF15113, whole genome s...    86   5e-15
UniRef50_A7SM30 Cluster: Predicted protein; n=1; Nematostella ve...    86   5e-15
UniRef50_UPI00006A231D Cluster: Brother of CDO precursor (Protei...    86   6e-15
UniRef50_UPI000065EC1F Cluster: Homolog of Homo sapiens "Obscuri...    86   6e-15
UniRef50_Q0E9F2 Cluster: CG33141-PB, isoform B; n=9; Diptera|Rep...    86   6e-15
UniRef50_A2AAJ9 Cluster: Obscurin; n=10; Eutheria|Rep: Obscurin ...    86   6e-15
UniRef50_Q9U8G8 Cluster: Lacunin precursor; n=1; Manduca sexta|R...    85   8e-15
UniRef50_P0C5E3 Cluster: Palladin; n=24; Amniota|Rep: Palladin -...    85   8e-15
UniRef50_Q5VST9 Cluster: Obscurin; n=50; Amniota|Rep: Obscurin -...    85   8e-15
UniRef50_Q7PMY4 Cluster: ENSANGP00000014155; n=2; Culicidae|Rep:...    85   1e-14
UniRef50_Q17AF2 Cluster: Myosin light chain kinase; n=1; Aedes a...    85   1e-14
UniRef50_Q308M3 Cluster: Protein tyrosine phosphatase receptor t...    85   1e-14
UniRef50_UPI00015B4DC5 Cluster: PREDICTED: similar to ENSANGP000...    85   1e-14
UniRef50_UPI0000F1F64B Cluster: PREDICTED: hypothetical protein;...    85   1e-14
UniRef50_Q4R5Y9 Cluster: Testis cDNA, clone: QtsA-19723, similar...    85   1e-14
UniRef50_Q9VCT4 Cluster: CG6669-PA; n=8; Diptera|Rep: CG6669-PA ...    85   1e-14
UniRef50_Q9U4G1 Cluster: CG16857-PA; n=8; Endopterygota|Rep: CG1...    85   1e-14
UniRef50_A7TAR2 Cluster: Predicted protein; n=1; Nematostella ve...    85   1e-14
UniRef50_A7T325 Cluster: Predicted protein; n=1; Nematostella ve...    85   1e-14
UniRef50_UPI0000F1FF89 Cluster: PREDICTED: hypothetical protein;...    84   2e-14
UniRef50_Q4S6A6 Cluster: Chromosome 9 SCAF14729, whole genome sh...    84   2e-14
UniRef50_A5PMX0 Cluster: Novel protein; n=4; Danio rerio|Rep: No...    84   2e-14
UniRef50_UPI0000E4A76B Cluster: PREDICTED: similar to NCAM-140; ...    84   3e-14
UniRef50_Q4SF99 Cluster: Chromosome undetermined SCAF14606, whol...    84   3e-14
UniRef50_Q2IPN8 Cluster: Putative vgr-related protein; n=1; Anae...    84   3e-14
UniRef50_Q7QJK9 Cluster: ENSANGP00000010739; n=1; Anopheles gamb...    84   3e-14
UniRef50_Q21043 Cluster: Putative uncharacterized protein pxn-2;...    84   3e-14
UniRef50_A7T5G7 Cluster: Predicted protein; n=1; Nematostella ve...    84   3e-14
UniRef50_Q8WX93 Cluster: Palladin; n=14; Euarchontoglires|Rep: P...    84   3e-14
UniRef50_UPI0000DB6FFA Cluster: PREDICTED: similar to Papilin CG...    83   3e-14
UniRef50_Q4SAP3 Cluster: Chromosome undetermined SCAF14681, whol...    83   3e-14
UniRef50_Q25198 Cluster: Receptor tyrosine kinase 90; n=1; Hydra...    83   3e-14
UniRef50_Q17HV8 Cluster: Myomesin; n=3; Culicidae|Rep: Myomesin ...    83   3e-14
UniRef50_A7S735 Cluster: Predicted protein; n=1; Nematostella ve...    83   3e-14
UniRef50_UPI0000DB7435 Cluster: PREDICTED: similar to unc-5 homo...    83   4e-14
UniRef50_UPI00015A6DFF Cluster: UPI00015A6DFF related cluster; n...    83   4e-14
UniRef50_Q4RQR3 Cluster: Chromosome 2 SCAF15004, whole genome sh...    83   4e-14
UniRef50_A7RYG0 Cluster: Predicted protein; n=1; Nematostella ve...    83   4e-14
UniRef50_Q4TBU1 Cluster: Chromosome undetermined SCAF7089, whole...    83   6e-14
UniRef50_P79757 Cluster: Connectin/titin; n=3; Amniota|Rep: Conn...    83   6e-14
UniRef50_O44328 Cluster: Receptor tyrosine phosphatase; n=6; Eum...    83   6e-14
UniRef50_Q9UBF9 Cluster: Myotilin; n=18; Tetrapoda|Rep: Myotilin...    83   6e-14
UniRef50_UPI00015B6345 Cluster: PREDICTED: similar to CG33141-PB...    82   8e-14
UniRef50_Q9W4Y6 Cluster: CG32796-PB, isoform B; n=4; Drosophila ...    82   8e-14
UniRef50_Q1RKQ9 Cluster: IP03437p; n=12; Diptera|Rep: IP03437p -...    82   8e-14
UniRef50_UPI000069DD8B Cluster: Leucine-rich repeats and immunog...    82   1e-13
UniRef50_UPI0000EB3119 Cluster: UPI0000EB3119 related cluster; n...    82   1e-13
UniRef50_UPI00015B4AAE Cluster: PREDICTED: hypothetical protein;...    81   1e-13
UniRef50_UPI00006A2827 Cluster: UPI00006A2827 related cluster; n...    81   1e-13
UniRef50_Q9BN17 Cluster: Echinoid; n=10; Diptera|Rep: Echinoid -...    81   1e-13
UniRef50_Q290N6 Cluster: GA21440-PA; n=1; Drosophila pseudoobscu...    81   1e-13
UniRef50_A7T115 Cluster: Predicted protein; n=2; Nematostella ve...    81   1e-13
UniRef50_Q8T101 Cluster: Titin-like protein; n=4; Endopterygota|...    81   2e-13
UniRef50_UPI0000F1EEC5 Cluster: PREDICTED: similar to Immunoglob...    81   2e-13
UniRef50_A2RVD9 Cluster: IP11255p; n=4; Diptera|Rep: IP11255p - ...    81   2e-13
UniRef50_Q9PVD5 Cluster: Netrin receptor unc-5 homolog; n=2; Pet...    81   2e-13
UniRef50_UPI0000F2138A Cluster: PREDICTED: hypothetical protein;...    80   3e-13
UniRef50_UPI0000DB6D94 Cluster: PREDICTED: similar to CG33274-PA...    80   3e-13
UniRef50_UPI00004D30C0 Cluster: Sialoadhesin precursor (Sialic a...    80   3e-13
UniRef50_Q24327 Cluster: Gp160-Dtrk precursor; n=4; Sophophora|R...    80   3e-13
UniRef50_A7RGL4 Cluster: Predicted protein; n=1; Nematostella ve...    80   3e-13
UniRef50_UPI00015B62AD Cluster: PREDICTED: similar to GA13389-PA...    80   4e-13
UniRef50_UPI00015B48D7 Cluster: PREDICTED: similar to lachesin; ...    80   4e-13
UniRef50_Q4S1S8 Cluster: Chromosome undetermined SCAF14764, whol...    80   4e-13
UniRef50_Q7PF94 Cluster: ENSANGP00000024414; n=1; Anopheles gamb...    80   4e-13
UniRef50_Q17AF0 Cluster: Novex-3; n=2; Culicidae|Rep: Novex-3 - ...    80   4e-13
UniRef50_Q501U7 Cluster: Ttnl protein; n=2; Danio rerio|Rep: Ttn...    79   6e-13
UniRef50_Q4THV8 Cluster: Chromosome undetermined SCAF2631, whole...    79   6e-13
UniRef50_Q2WF53 Cluster: Neurotrimin; n=9; Clupeocephala|Rep: Ne...    79   6e-13
UniRef50_A2A344 Cluster: ADAMTS-like 1; n=29; Euteleostomi|Rep: ...    79   6e-13
UniRef50_Q4RU89 Cluster: Chromosome 1 SCAF14995, whole genome sh...    79   7e-13
UniRef50_Q86GD6 Cluster: Projectin; n=1; Procambarus clarkii|Rep...    79   7e-13
UniRef50_Q7PRK4 Cluster: ENSANGP00000000600; n=1; Anopheles gamb...    79   7e-13
UniRef50_UPI0000E4754C Cluster: PREDICTED: similar to DDM36; n=1...    79   1e-12
UniRef50_UPI0000D55EBD Cluster: PREDICTED: similar to CG16857-PA...    79   1e-12
UniRef50_UPI00006A0C09 Cluster: obscurin, cytoskeletal calmoduli...    78   1e-12
UniRef50_Q4T3W5 Cluster: Chromosome undetermined SCAF9901, whole...    78   1e-12
UniRef50_Q4SXT7 Cluster: Chromosome undetermined SCAF12335, whol...    78   1e-12
UniRef50_Q3MHW8 Cluster: PALLD protein; n=7; Euteleostomi|Rep: P...    78   1e-12
UniRef50_Q28939 Cluster: Vascular cell adhesion molecule precurs...    78   1e-12
UniRef50_P17948 Cluster: Vascular endothelial growth factor rece...    78   1e-12
UniRef50_Q14982 Cluster: Opioid-binding protein/cell adhesion mo...    78   1e-12
UniRef50_Q03142 Cluster: Fibroblast growth factor receptor 4 pre...    78   1e-12
UniRef50_UPI00015B4F8B Cluster: PREDICTED: similar to lachesin, ...    78   2e-12
UniRef50_UPI0000F1E7B2 Cluster: PREDICTED: hypothetical protein;...    78   2e-12
UniRef50_UPI0000DBF2C2 Cluster: PTK7 protein tyrosine kinase 7; ...    78   2e-12
UniRef50_Q58EP4 Cluster: LOC572412 protein; n=2; Danio rerio|Rep...    78   2e-12
UniRef50_A5JTW0 Cluster: Kirrel; n=4; Clupeocephala|Rep: Kirrel ...    78   2e-12
UniRef50_Q8WR61 Cluster: Hemolin; n=2; Noctuoidea|Rep: Hemolin -...    78   2e-12
UniRef50_Q7PXZ1 Cluster: ENSANGP00000022061; n=1; Anopheles gamb...    78   2e-12
UniRef50_A7T347 Cluster: Predicted protein; n=7; Nematostella ve...    78   2e-12
UniRef50_Q5W433 Cluster: Sialic-acid binding protein-4 precursor...    77   2e-12
UniRef50_Q59F30 Cluster: Fibroblast growth factor receptor 4 var...    77   2e-12
UniRef50_Q62230 Cluster: Sialoadhesin precursor; n=9; Murinae|Re...    77   2e-12
UniRef50_Q4SLN7 Cluster: Chromosome 15 SCAF14556, whole genome s...    77   3e-12
UniRef50_A7MB72 Cluster: MGC166429 protein; n=4; Tetrapoda|Rep: ...    77   3e-12
UniRef50_A7SJL2 Cluster: Predicted protein; n=1; Nematostella ve...    77   3e-12
UniRef50_Q86TC9 Cluster: Myopalladin; n=20; Amniota|Rep: Myopall...    77   3e-12
UniRef50_Q965M2 Cluster: Putative uncharacterized protein; n=3; ...    77   4e-12
UniRef50_Q7JN85 Cluster: Twitchin; n=6; Bilateria|Rep: Twitchin ...    77   4e-12
UniRef50_A7S4M0 Cluster: Predicted protein; n=2; Nematostella ve...    77   4e-12
UniRef50_P15364 Cluster: Protein amalgam precursor; n=6; melanog...    77   4e-12
UniRef50_UPI0000DB7559 Cluster: PREDICTED: similar to sticks and...    76   5e-12
UniRef50_Q17G58 Cluster: Lachesin; n=3; Culicidae|Rep: Lachesin ...    76   5e-12
UniRef50_Q868Z9 Cluster: Papilin precursor; n=8; cellular organi...    76   5e-12
UniRef50_P43121 Cluster: Cell surface glycoprotein MUC18 precurs...    76   5e-12
UniRef50_Q8N3J6 Cluster: Cell adhesion molecule 2 precursor; n=3...    76   5e-12
UniRef50_UPI0000DB6DA8 Cluster: PREDICTED: similar to CG32387-PB...    76   7e-12
UniRef50_Q16UT3 Cluster: Papilin; n=1; Aedes aegypti|Rep: Papili...    76   7e-12
UniRef50_P06731 Cluster: Carcinoembryonic antigen-related cell a...    76   7e-12
UniRef50_Q7PW77 Cluster: ENSANGP00000005214; n=1; Anopheles gamb...    75   9e-12
UniRef50_A7RT95 Cluster: Predicted protein; n=1; Nematostella ve...    75   9e-12
UniRef50_Q9V787 Cluster: Hibris; n=4; Sophophora|Rep: Hibris - D...    75   1e-11
UniRef50_A7UQ11 Cluster: Putative uncharacterized protein; n=1; ...    75   1e-11
UniRef50_UPI0001556498 Cluster: PREDICTED: similar to obscurin, ...    75   2e-11
UniRef50_UPI0000DB7433 Cluster: PREDICTED: similar to unc-5 CG81...    75   2e-11
UniRef50_Q4T6R9 Cluster: Chromosome undetermined SCAF8634, whole...    75   2e-11
UniRef50_Q4T444 Cluster: Chromosome undetermined SCAF9829, whole...    75   2e-11
UniRef50_Q9VFU7 Cluster: CG14372-PB; n=5; Endopterygota|Rep: CG1...    75   2e-11
UniRef50_Q8IZU9 Cluster: Kin of IRRE-like protein 3 precursor; n...    75   2e-11
UniRef50_Q96J84 Cluster: Kin of IRRE-like protein 1 precursor; n...    75   2e-11
UniRef50_Q95YM9 Cluster: Fibroblast growth factor receptor precu...    75   2e-11
UniRef50_Q8NFZ8 Cluster: Cell adhesion molecule 4 precursor; n=2...    75   2e-11
UniRef50_UPI0000F20798 Cluster: PREDICTED: hypothetical protein;...    74   2e-11
UniRef50_Q8IP70 Cluster: CG31814-PA; n=9; Endopterygota|Rep: CG3...    74   2e-11
UniRef50_Q7PRJ5 Cluster: ENSANGP00000024207; n=3; Endopterygota|...    74   2e-11
UniRef50_UPI0001554C79 Cluster: PREDICTED: hypothetical protein;...    74   3e-11
UniRef50_UPI0000D55B25 Cluster: PREDICTED: similar to CG6669-PA;...    74   3e-11
UniRef50_UPI000051A102 Cluster: PREDICTED: similar to CG31646-PA...    74   3e-11
UniRef50_Q4RFF0 Cluster: Chromosome 8 SCAF15119, whole genome sh...    74   3e-11
UniRef50_Q4RE90 Cluster: Chromosome undetermined SCAF15134, whol...    74   3e-11
UniRef50_Q4RE89 Cluster: Chromosome undetermined SCAF15134, whol...    74   3e-11
UniRef50_Q16XM4 Cluster: Cell adhesion molecule; n=2; Culicidae|...    74   3e-11
UniRef50_Q6UY18 Cluster: Leucine-rich repeat neuronal protein 6D...    74   3e-11
UniRef50_UPI000065F0CA Cluster: Homolog of Homo sapiens "MAM dom...    73   4e-11
UniRef50_UPI000065EECD Cluster: Homolog of Brachydanio rerio "Ob...    73   4e-11
UniRef50_Q6NY23 Cluster: Zgc:64208; n=10; Clupeocephala|Rep: Zgc...    73   4e-11
UniRef50_Q2EGT7 Cluster: Limbic system-associated membrane prote...    73   4e-11
UniRef50_Q9VMN9 Cluster: CG14010-PA; n=2; Diptera|Rep: CG14010-P...    73   4e-11
UniRef50_Q173C9 Cluster: Netrin receptor; n=1; Aedes aegypti|Rep...    73   4e-11
UniRef50_A0NBD2 Cluster: ENSANGP00000031587; n=1; Anopheles gamb...    73   4e-11
UniRef50_Q9W4R3 Cluster: CG32791-PA; n=6; Endopterygota|Rep: CG3...    73   6e-11
UniRef50_Q9VHQ8 Cluster: CG31369-PA; n=8; Endopterygota|Rep: CG3...    73   6e-11
UniRef50_Q13449 Cluster: Limbic system-associated membrane prote...    73   6e-11
UniRef50_UPI00006A03AF Cluster: Sialic acid-binding Ig-like lect...    72   8e-11
UniRef50_UPI000065FE6C Cluster: Homolog of Homo sapiens "Carcino...    72   8e-11
UniRef50_Q5IFI2 Cluster: Gicerin; n=5; Danio rerio|Rep: Gicerin ...    72   8e-11
UniRef50_UPI00015B5C2D Cluster: PREDICTED: similar to lachesin; ...    72   1e-10
UniRef50_UPI00015B5A89 Cluster: PREDICTED: similar to papilin; n...    72   1e-10
UniRef50_UPI0000F2DD14 Cluster: PREDICTED: similar to IGSF4D pro...    72   1e-10
UniRef50_UPI0000D55579 Cluster: PREDICTED: similar to CG14521-PA...    72   1e-10
UniRef50_Q9VMN6 Cluster: CG31646-PA; n=9; Endopterygota|Rep: CG3...    72   1e-10
UniRef50_A7RZ85 Cluster: Predicted protein; n=1; Nematostella ve...    72   1e-10
UniRef50_Q4ACB4 Cluster: Mahya; n=3; Endopterygota|Rep: Mahya - ...    71   1e-10
UniRef50_UPI0000F1E3FB Cluster: PREDICTED: similar to novel immu...    71   2e-10
UniRef50_UPI0000F1DED3 Cluster: PREDICTED: similar to sialic-aci...    71   2e-10
UniRef50_UPI0000E80635 Cluster: PREDICTED: similar to papilin; n...    71   2e-10
UniRef50_Q22040 Cluster: Putative uncharacterized protein SSSD1....    71   2e-10
UniRef50_A7SZ31 Cluster: Predicted protein; n=1; Nematostella ve...    71   2e-10
UniRef50_UPI0000E472F6 Cluster: PREDICTED: similar to myosin lig...    71   3e-10
UniRef50_Q58QC3 Cluster: Nephrin; n=3; Euteleostomi|Rep: Nephrin...    71   3e-10
UniRef50_Q17HV9 Cluster: Titin; n=5; Endopterygota|Rep: Titin - ...    71   3e-10
UniRef50_UPI00015B62AB Cluster: PREDICTED: similar to CG18255-PA...    70   3e-10
UniRef50_UPI0000D55947 Cluster: PREDICTED: similar to CG33141-PA...    70   3e-10
UniRef50_Q4SI34 Cluster: Chromosome 5 SCAF14581, whole genome sh...    70   3e-10
UniRef50_Q9VM64 Cluster: CG9211-PA; n=8; Sophophora|Rep: CG9211-...    70   3e-10
UniRef50_Q9U3P2 Cluster: Putative uncharacterized protein syg-2;...    70   3e-10
UniRef50_Q61PF2 Cluster: Putative uncharacterized protein CBG075...    70   3e-10
UniRef50_Q17J18 Cluster: Tyrosine-protein kinase; n=4; Endoptery...    70   3e-10
UniRef50_UPI00015B5C00 Cluster: PREDICTED: similar to VEGFR-A sp...    70   4e-10
UniRef50_UPI0000F1D6A2 Cluster: PREDICTED: hypothetical protein;...    70   4e-10
UniRef50_A0A4W4 Cluster: Kilon; n=5; Clupeocephala|Rep: Kilon - ...    70   4e-10
UniRef50_A7S0R0 Cluster: Predicted protein; n=1; Nematostella ve...    70   4e-10
UniRef50_Q9BZZ2 Cluster: Sialoadhesin precursor; n=17; Eutheria|...    70   4e-10
UniRef50_Q8MQ86 Cluster: Putative uncharacterized protein F02G3....    69   6e-10
UniRef50_Q96LA6 Cluster: Fc receptor-like protein 1; n=19; Euthe...    69   6e-10
UniRef50_Q4S3Q6 Cluster: Chromosome 17 SCAF14747, whole genome s...    69   8e-10
UniRef50_Q16Q42 Cluster: Putative uncharacterized protein; n=1; ...    69   8e-10
UniRef50_A7TBA8 Cluster: Predicted protein; n=1; Nematostella ve...    69   8e-10
UniRef50_A1ZAB1 Cluster: CG8434-PA; n=2; Sophophora|Rep: CG8434-...    69   8e-10
UniRef50_UPI00006A1BAE Cluster: B-cell receptor CD22 precursor (...    69   1e-09
UniRef50_Q26475 Cluster: REGA-1 protein precursor; n=1; Schistoc...    68   1e-09
UniRef50_Q1HPN0 Cluster: Insulin-related peptide binding protein...    68   1e-09
UniRef50_A7T0T0 Cluster: Predicted protein; n=1; Nematostella ve...    68   1e-09
UniRef50_A7RNN5 Cluster: Predicted protein; n=1; Nematostella ve...    68   1e-09
UniRef50_UPI0000DB720F Cluster: PREDICTED: similar to CG14964-PA...    68   2e-09
UniRef50_UPI00004D96E1 Cluster: adlican; n=1; Xenopus tropicalis...    68   2e-09
UniRef50_UPI000066082B Cluster: Homolog of Homo sapiens "CD22 pr...    68   2e-09
UniRef50_Q9VAR6 Cluster: CG14521-PA; n=5; Diptera|Rep: CG14521-P...    68   2e-09
UniRef50_Q6ZNM1 Cluster: FLJ00259 protein; n=16; Amniota|Rep: FL...    68   2e-09
UniRef50_O95428 Cluster: Papilin; n=6; Eutheria|Rep: Papilin - H...    68   2e-09
UniRef50_UPI00004D91EC Cluster: WAP four-disulfide core domain p...    67   2e-09
UniRef50_Q9VZT8 Cluster: CG14964-PA; n=4; Diptera|Rep: CG14964-P...    67   2e-09
UniRef50_UPI00005A3E04 Cluster: PREDICTED: similar to protein ty...    67   3e-09

>UniRef50_Q174G3 Cluster: Roundabout; n=5; Aedes aegypti|Rep:
            Roundabout - Aedes aegypti (Yellowfever mosquito)
          Length = 1345

 Score =  932 bits (2307), Expect = 0.0
 Identities = 479/1042 (45%), Positives = 650/1042 (62%), Gaps = 34/1042 (3%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGLFFL 69
            P IIE P+D TV RH+PATLNC+A G P+P I+WYK G L  +   +HR  LPAG LFFL
Sbjct: 83   PRIIEHPIDTTVPRHEPATLNCKAEGVPAPTIQWYKDGSLLKIFPGSHRIFLPAGELFFL 142

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
            +  + R  SDAGVYWCEA N  G ARSRNATL VAVLRE+FRLEP+S + AQG+TV+LEC
Sbjct: 143  KVVNSRRESDAGVYWCEAHNENGVARSRNATLQVAVLREDFRLEPQSTRVAQGETVLLEC 202

Query: 130  LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
             PP+G PEP V W+KNGQ L  +   R+ +VDGGNL IQD RQTD G+YQCIARN  G R
Sbjct: 203  GPPKGIPEPTVAWRKNGQKLDVESSKRIRVVDGGNLAIQDVRQTDEGQYQCIARNQVGVR 262

Query: 190  ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249
            ESA+A LK+H+KP+LI GP D     GSSVTFQCRVGGDP+PDVLWRRSA GGNMPL RV
Sbjct: 263  ESAVAFLKVHVKPFLIRGPHDSTIVEGSSVTFQCRVGGDPMPDVLWRRSASGGNMPLDRV 322

Query: 250  KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309
             +L+D SLRL+NV+L DEGEYSCEA+N+VG +SA+G L V+ PP + + P    VE+ + 
Sbjct: 323  HILEDRSLRLENVVLDDEGEYSCEADNAVGTISATGTLNVHSPPHLVIRPVQQVVEAPHD 382

Query: 310  ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
            A F C + GRP+PT FWS+EGNRT+IFPG   D++  +   +G++VLTI  T K D+   
Sbjct: 383  ATFECRSEGRPKPTTFWSIEGNRTLIFPGSKFDRFETSTTVEGLSVLTIPQTTKADNGLI 442

Query: 370  IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
            +VCS+VN  GS  VR +LTV S DDRPPPII  GPSNQTLP+ S+   PC A+  P PII
Sbjct: 443  VVCSSVNSVGSISVRARLTVASQDDRPPPIIILGPSNQTLPLGSVVALPCKAVGNPNPII 502

Query: 430  AWYFEGEALIQNHRRNVTNDGTLVLKDLDKS-DSGTYTCVASSRHGKYVWSGALLVDSPI 488
            +WY +G  +I + R N+T++GTL++ DLDKS D G YTCVASSR GK  WS  L ++SP 
Sbjct: 503  SWYLDGNPVINSERTNMTDNGTLIIHDLDKSTDQGLYTCVASSRSGKATWSAYLRLESPT 562

Query: 489  NPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETL 548
            NPNIHFFRA + S+ P  P KP   NVT++S+T+SW  + K G+S I GY +EVF+ +  
Sbjct: 563  NPNIHFFRAHEPSAFPTAPGKPQVVNVTNSSITISWLPSIKSGASDINGYLIEVFATDM- 621

Query: 549  SGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVG 608
                    ++GW+ I  ++  T Y    +   ++Y FIVR EN  GL  PS +SD VT+G
Sbjct: 622  --------AKGWIPIPYKLSSTSYTYSPVTADVSYTFIVRAENDQGLGIPSLMSDPVTIG 673

Query: 609  DDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYF 668
             D N    G  + N +E +  + +  +V L+EA   DS +++L WEI+N  Y+EG +IY 
Sbjct: 674  RDFN---HGEDI-NLSEAQATLSSGSVVNLLEANASDSSSVRLAWEIVNGQYVEGFYIYS 729

Query: 669  RPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLD 728
            R + N    Y+  T+LH    S   I  L KYT+YEFFL+PF+K  EG+PSNSR   TL+
Sbjct: 730  RQI-NSNGTYKTLTVLHGGGASACTINGLEKYTEYEFFLVPFFKTIEGRPSNSRTTWTLE 788

Query: 729  DVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTT 788
            DVP   P+N+E  +LNT+ V+LKW PP     NG +  Y++++   D+  N S V  N T
Sbjct: 789  DVPSASPVNMEAVLLNTSAVYLKWEPPANHSLNGKLKNYHIIIRGYDI-HNISKVLTNMT 847

Query: 789  VH-QATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDL-LSRYPMNG 846
            V   +  L++ NL++GV+YSV IAA T +G+GP+S      +D  +  LD   +RYP+N 
Sbjct: 848  VDGDSPKLLLANLSAGVTYSVSIAASTRVGMGPYSAPSILRLDPHTKRLDQGYTRYPINH 907

Query: 847  EVSIVAGDFVMETWFYFLIGAIVLFKIIVIAGIIYVRKYNIFAKKSALPNIYDSNGTSLV 906
            + S    D + +TWF  L+G+I+   + +    +  R+   F K S+L N++ ++    V
Sbjct: 908  DYS---HDILTQTWFIILLGSIIAIIVFLFGATVIFRRIQ-FMKHSSLNNMHGNHAIGTV 963

Query: 907  TQMNIKAAVSLSHPLTSCYNKNTVTKTESLLWMENQPGVCLSGNQTSQSKEKTNFEYDKV 966
             +      + L+           V +  S +  E         N  +        +Y+++
Sbjct: 964  RKF---PTLPLNPNGVWIDPGGGVWRQASEITKEAITDYAAVSNAPTLPLP----DYERL 1016

Query: 967  TH-QLPEYAEVT--SARANEWNTNKTATSPAAYASVTLVANTRQCVSSLGWFPPGGKNVD 1023
            +   +P+YAEV   S+  N+   + +  +  AYAS TLV  +    +S G     G  + 
Sbjct: 1017 SPLNMPDYAEVAGCSSFKNDLGGSPSYDNYGAYASTTLVGRSIGNAASNGTSVASGAPMF 1076

Query: 1024 TFDNRYGADEELYPASNGGYYN 1045
                     + +Y A    +YN
Sbjct: 1077 AQQQNQFDGKNVYSAPTSCHYN 1098


>UniRef50_UPI0000D56E5C Cluster: PREDICTED: similar to CG5423-PA; n=1;
            Tribolium castaneum|Rep: PREDICTED: similar to CG5423-PA
            - Tribolium castaneum
          Length = 1136

 Score =  925 bits (2290), Expect = 0.0
 Identities = 479/1055 (45%), Positives = 649/1055 (61%), Gaps = 59/1055 (5%)

Query: 8    SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-----THRSILP 62
            S + P I E P+D TVARH+PATLNC A G P P I W+K G+ + +      +HR +LP
Sbjct: 67   SQQPPRITEHPVDTTVARHEPATLNCHASGEPEPTITWFKDGMTLRTAPQDARSHRVLLP 126

Query: 63   AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122
            AG LFFLR    R  SDAGVYWCEA+N+ G ARSRNATL VAVLR+EFRLEP+S + A G
Sbjct: 127  AGNLFFLRVVQSRKESDAGVYWCEASNALGKARSRNATLTVAVLRDEFRLEPQSTRVAAG 186

Query: 123  DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
            + +V+EC PPRG+PEP V+W+K+G TL  +G  R+ LVDG NL I D + +D GRYQC+A
Sbjct: 187  EDIVMECAPPRGTPEPQVFWRKDGHTLEVEG--RLKLVDGSNLAITDTKPSDDGRYQCVA 244

Query: 183  RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
            +N AG RESA+A LK+++KP+LI  PED  A  GS+V F C VGGDPLPDVLWRR+A GG
Sbjct: 245  KNTAGVRESAVAILKVYVKPFLIKPPEDKTALVGSTVDFPCAVGGDPLPDVLWRRNAAGG 304

Query: 243  NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
             MPLGRV+VL+D +LRL+ + L D+G Y+CEA+N  GA++A+  LTV+ PP++   P + 
Sbjct: 305  TMPLGRVRVLEDRTLRLERITLLDQGRYTCEADNYAGAITATALLTVHAPPTLTTRPLAQ 364

Query: 303  NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
             VES     F C   G P+P +FWS EG+RT+I+PG S   Y  T V +G + LT+    
Sbjct: 365  TVESNRDVSFHCNVEGSPKPFIFWSFEGDRTLIYPGTSTGNYQVTTV-EGKSTLTLKQAQ 423

Query: 363  KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
              +S   I+CSAVN AGS+  R +LTVTS ++ PPP+I  GP NQTLPI S+A   C A 
Sbjct: 424  PQNSGTVIICSAVNAAGSASTRTRLTVTSREEHPPPVIIRGPVNQTLPINSVAFLSCEAS 483

Query: 423  CTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482
              P P+I+WY E   +   +R N TN G + + +L K DSG YTCVASSR GK  WSG L
Sbjct: 484  GNPTPVISWYKENHPVTSTNRINTTNPGLVEIHNLQKDDSGLYTCVASSRSGKATWSGHL 543

Query: 483  LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEV 542
            LV++P NPNI+FF+A +   LPGPP++P   N ++ SVT++W QNNKIGSSS+LGYQ+E+
Sbjct: 544  LVENPKNPNINFFKAPEAIMLPGPPSRPHALNQSEGSVTITWGQNNKIGSSSLLGYQIEL 603

Query: 543  FSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602
            F RE      TP     W V+ARRV    Y    L P + Y F+VR EN HGL  PS +S
Sbjct: 604  FGREE---GVTPT----WTVVARRVQGPTYTQHLLSPSVPYTFLVRAENGHGLGPPSQLS 656

Query: 603  DSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLE 662
            D + VG D+   W    V+  +E R +++   IV L EA P+ S  IKL+WEIL+  Y+E
Sbjct: 657  DIIIVGPDTAQNWGNPEVTVLSEARASLVKGDIVRLSEAIPVLSTAIKLVWEILDAQYVE 716

Query: 663  GLFIYFRPLD---NITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPS 719
            GL+IY+  LD   ++   Y M T+LH+   S F + +L K+++YEFFL+PFYK  EG+PS
Sbjct: 717  GLYIYYVTLDGPSDLPKPYSMLTVLHTGGASSFTVNNLAKWSRYEFFLVPFYKTVEGQPS 776

Query: 720  NSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPAN 779
            NSR  +TL+DVP   P ++E  +LN+T V+LKW PP  +  NG + GY +     ++ AN
Sbjct: 777  NSRTVRTLEDVPVEAPTSMEALLLNSTAVYLKWKPPPSETLNGDLQGYKI-----EIKAN 831

Query: 780  KSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLL 839
             +      TV    +L++ NLT+GV+Y+V++AA T  GLGPFS      +D  S   D  
Sbjct: 832  GTGTTDTVTVGTTPTLLLGNLTAGVAYTVKVAAMTRAGLGPFSSAAILRLDPASRHNDHH 891

Query: 840  SRYPMNGEVSIVAGDFVMETWFYFLIGAIVLFKIIVIAGIIYVRKYNIFAKKSALPNIYD 899
             + P    + + +GDF+ ETWF  L+ ++V   +++   ++ VR+  +  KK+  P+   
Sbjct: 892  HQKP----IDMQSGDFITETWFMALLISMVSVMVLLFGAMLLVRRRQMLTKKTLTPS--R 945

Query: 900  SNGTSLVTQMNIKAAVSLSHPLTSCYNKNTVTKTESLLWMENQPGVCLSGNQTSQSKEKT 959
            SNG  L T +  K    L     +  + +      S L  E    +    +    SK   
Sbjct: 946  SNGAVLTTPLASKTETPLWLDKDALPDYSNSLPEYSKLTPEVNLHLNPRPDHLDCSK-YM 1004

Query: 960  NFEYDKVTHQLPEYAEVTSARANEWNTNKTATSPAAYASVTLVANTRQCVSSLGWFPPGG 1019
              E +  +  L +YAEV +++          TSPA YA+ TLV   R+ V    W     
Sbjct: 1005 QVEKEYASPNLADYAEVEASQ---------VTSPAPYATTTLVTGGRRMV----W----- 1046

Query: 1020 KNVDTFDNRYGADEELYPASNGGYYNRNVYSEKYF 1054
                        +E  YP+ NGGYYNR VYS+ YF
Sbjct: 1047 -----------VEEPPYPSHNGGYYNRKVYSDSYF 1070


>UniRef50_Q9GPP6 Cluster: Roundabout 3; n=4; Diptera|Rep: Roundabout
           3 - Drosophila melanogaster (Fruit fly)
          Length = 1342

 Score =  880 bits (2178), Expect = 0.0
 Identities = 434/907 (47%), Positives = 596/907 (65%), Gaps = 28/907 (3%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV--LVVSDTHRSILPAGGLFFL 69
           P I+E P+D TV RH+PATLNC+A GSP+P I+WYK GV   ++  +HR  LPAGGLFFL
Sbjct: 23  PRIVEHPIDTTVPRHEPATLNCKAEGSPTPTIQWYKDGVPLKILPGSHRITLPAGGLFFL 82

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
           +  + R  +DAG+YWCEA N  G ARSRNATL VAVLR+EFRLEP++ + AQGDT +LEC
Sbjct: 83  KVVNSRRETDAGIYWCEAKNELGVARSRNATLQVAVLRDEFRLEPQNTRIAQGDTALLEC 142

Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
             PRG PEP V WKK GQ L  +G  R+ +VDGGNL IQDARQTD G+YQCIA+N  G R
Sbjct: 143 AAPRGIPEPTVTWKKGGQKLDLEGSKRVRIVDGGNLAIQDARQTDEGQYQCIAKNPVGVR 202

Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249
           ES++ATLK+H+KPY+I GP D     G+SVTF CRVGGDP+PDVLW R+A GGNMPL RV
Sbjct: 203 ESSLATLKVHVKPYIIRGPHDQTVLEGASVTFPCRVGGDPMPDVLWLRTASGGNMPLDRV 262

Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309
            VL+D SLRL+ V +ADEGEYSCEA+N VGA++A G LTVY PP     P S +VE G  
Sbjct: 263 SVLEDRSLRLERVTIADEGEYSCEADNVVGAITAMGTLTVYAPPKFIQRPASKSVELGAD 322

Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGM-SRDKYHATAVFDGVTVLTINDTDKNDSRN 368
             F C A G P+PT+FW+++ N T+IFPG    D++H+    +G ++LT+    + D   
Sbjct: 323 TSFECRAIGNPKPTIFWTIKNNSTLIFPGAPPLDRFHSLNTEEGHSILTLTRFQRTDKDL 382

Query: 369 TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428
            I+C+A+N   S   R +L++ S +DRPPPII +GP NQTLPIKS+A   C AI  P P 
Sbjct: 383 VILCNAMNEVASITSRVQLSLDSQEDRPPPIIISGPVNQTLPIKSLATLQCKAIGLPSPT 442

Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDK-SDSGTYTCVASSRHGKYVWSGALLVDSP 487
           I+WY +G  +  + + N+T  G L++ DLD+  D G YTCVASSR GK  WSG L ++ P
Sbjct: 443 ISWYRDGIPVQPSSKLNITTSGDLIISDLDRQQDQGLYTCVASSRAGKSTWSGFLRIELP 502

Query: 488 INPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRET 547
            NPNI F+RA + +  P  P +P   N T +++T+ W  ++K G+SS LGY VE++    
Sbjct: 503 TNPNIKFYRAPEQTKCPSAPGQPKILNATASALTIVWPTSDKAGASSFLGYSVEMY---- 558

Query: 548 LSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVT- 606
                    SR W+ IA R+ +  + V+SL  G  YMFIVR ENS G S PSP+S+ +T 
Sbjct: 559 -----CTNQSRTWIPIASRLSEPIFTVESLTQGAAYMFIVRAENSLGFSPPSPISEPITA 613

Query: 607 ---VGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEG 663
              VG    S   GT     ++    +  + +VEL+EA   DS T +L W+I +  Y+EG
Sbjct: 614 GKLVGVRDGSESTGTSQLLLSDVETLLQANDVVELLEANASDSTTARLSWDIDSGQYIEG 673

Query: 664 LFIYFRPLDNITIEYEMKTILHSND-VSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSR 722
            ++Y R L   + EY+M T+L+    +S   +  L K + YEFFL+PFYK   GKPSNSR
Sbjct: 674 FYLYARELH--SSEYKMVTLLNKGQGLSSCTVPGLAKASTYEFFLVPFYKSIVGKPSNSR 731

Query: 723 VAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPE-LQLQNGIITGYNVVVNWLDVPANKS 781
             +TL+DVP+ PP  +E    N T+V LKW PP+  + +NGI+T YNVVV  LDV  N +
Sbjct: 732 RMRTLEDVPEAPPYGMEAIQFNRTSVFLKWLPPQPNRTRNGILTSYNVVVKGLDV-HNTT 790

Query: 782 MVAINTTVHQAT-SLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDL-L 839
            +  N T+  AT +L++ NLT+GV+Y + +AA T +G+GPFS+     ID+R+  LD   
Sbjct: 791 RIFKNMTIDAATPTLLLANLTTGVTYYIAVAAATRVGVGPFSKPAVLRIDARTQSLDTGY 850

Query: 840 SRYPMNGEVSIVAGDFVMETWFYFLIGAIVLFKIIVIAGIIYVRKYNIFAKKSALPNIYD 899
           +RYP++ +   +A DF+ +TWF  L+G+I+   + ++  ++  ++Y  F K+++L +++ 
Sbjct: 851 TRYPISRD---IADDFLTQTWFIVLLGSIIAIIVFLLGALVLFKRYQ-FIKQTSLGSLHG 906

Query: 900 SNGTSLV 906
           ++    V
Sbjct: 907 NHAIGTV 913



 Score = 58.0 bits (134), Expect = 1e-06
 Identities = 50/189 (26%), Positives = 76/189 (40%), Gaps = 16/189 (8%)

Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
           PP I   P    V     A   C A G P PT+ W  +G    I PG  R     T    
Sbjct: 22  PPRIVEHPIDTTVPRHEPATLNCKAEGSPTPTIQWYKDGVPLKILPGSHR----ITLPAG 77

Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG---KLTVTSDDDRPPPIITNGPSNQT 408
           G+  L + ++ +        C A N  G +  R    ++ V  D+ R        P N  
Sbjct: 78  GLFFLKVVNSRRETDAGIYWCEAKNELGVARSRNATLQVAVLRDEFRLE------PQNTR 131

Query: 409 LPIKSMAVFPCTA-ICTPEPIIAWYFEGEAL-IQNHRR-NVTNDGTLVLKDLDKSDSGTY 465
           +     A+  C A    PEP + W   G+ L ++  +R  + + G L ++D  ++D G Y
Sbjct: 132 IAQGDTALLECAAPRGIPEPTVTWKKGGQKLDLEGSKRVRIVDGGNLAIQDARQTDEGQY 191

Query: 466 TCVASSRHG 474
            C+A +  G
Sbjct: 192 QCIAKNPVG 200


>UniRef50_Q9VQ08 Cluster: CG5481-PA; n=6; Diptera|Rep: CG5481-PA -
           Drosophila melanogaster (Fruit fly)
          Length = 1463

 Score =  722 bits (1784), Expect = 0.0
 Identities = 343/693 (49%), Positives = 469/693 (67%), Gaps = 19/693 (2%)

Query: 9   GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT--HRSILPAGGL 66
           GE P IIE P+D TV ++ P T NC+A G+P+P I+W+K G  + +DT  HR +LPAGGL
Sbjct: 88  GENPRIIEHPMDTTVPKNDPFTFNCQAEGNPTPTIQWFKDGRELKTDTGSHRIMLPAGGL 147

Query: 67  FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
           FFL+  H R  SDAG YWCEA N +G ARSRNATL VA LR+EFRLEP + + AQG+  +
Sbjct: 148 FFLKVIHSRRESDAGTYWCEAKNEFGVARSRNATLQVAFLRDEFRLEPANTRVAQGEVAL 207

Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
           +EC  PRGSPEP + W+KNGQTL   G+ R+ +VDGGNL IQ+ARQ+D GRYQC+ +N  
Sbjct: 208 MECGAPRGSPEPQISWRKNGQTLNLVGNKRIRIVDGGNLAIQEARQSDDGRYQCVVKNVV 267

Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
           GTRESA A LK+H++P+LI GP++  A  GSSV FQCR+GGDPLPDVLWRR+A GGNMPL
Sbjct: 268 GTRESATAFLKVHVRPFLIRGPQNQTAVVGSSVVFQCRIGGDPLPDVLWRRTASGGNMPL 327

Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
            RV VL+D SL+LD+V L D GEY+CEA+N+VG ++A+G LTV+ PP   + P +  VE 
Sbjct: 328 RRVHVLEDRSLKLDDVTLEDMGEYTCEADNAVGGITATGILTVHAPPKFVIRPKNQLVEI 387

Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
           G+   F C A G P PT++WSVEGN +++ PG    +   T   +G +VL+I    + DS
Sbjct: 388 GDEVLFECQANGHPRPTLYWSVEGNSSLLLPGYRDGRMEVTLTPEGRSVLSIARFAREDS 447

Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
              + C+A+N  GS   R  ++V +  + PPPII  GP NQTLP+KS+ V PC  + TP 
Sbjct: 448 GKVVTCNALNAVGSVSSRTVVSVDTQFELPPPIIEQGPVNQTLPVKSIVVLPCRTLGTPV 507

Query: 427 PIIAWYFEGEAL-IQNH-RRNVTNDGTLVLKDLDK-SDSGTYTCVASSRHGKYVWSGALL 483
           P ++WY +G  + +Q H RRN+++ G L + DL +  D G YTCVAS+R+GK  WSG L 
Sbjct: 508 PQVSWYLDGIPIDVQEHERRNLSDAGALTISDLQRHEDEGLYTCVASNRNGKSSWSGYLR 567

Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543
           +D+P NPNI FFRA ++S+ PGPP KP      + SVTLSW+++NK+G SS++GY +E+F
Sbjct: 568 LDTPTNPNIKFFRAPELSTYPGPPGKPQMVEKGENSVTLSWTRSNKVGGSSLVGYVIEMF 627

Query: 544 SRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
            +     N T     GWV +  RV  T +    L+PG+ Y F++R ENSHGLS PSP+S+
Sbjct: 628 GK-----NETD----GWVAVGTRVQNTTFTQTGLLPGVNYFFLIRAENSHGLSLPSPMSE 678

Query: 604 SVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEG 663
            +TVG    + +  +G+  S E R ++L+  +VEL  A+ +DS ++KL W+I+N  Y+EG
Sbjct: 679 PITVG----TRYFNSGLDLS-EARASLLSGDVVELSNASVVDSTSMKLTWQIINGKYVEG 733

Query: 664 LFIYFRPLDNITIEYEMKTILHSNDVSGFEITS 696
            ++Y R L N  +        ++N + G   TS
Sbjct: 734 FYVYARQLPNPIVNNPAPVTSNTNPLLGSTSTS 766



 Score =  178 bits (434), Expect = 7e-43
 Identities = 92/239 (38%), Positives = 143/239 (59%), Gaps = 7/239 (2%)

Query: 674  ITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDG 733
            +  +Y M TIL+    S   IT L +YT YEFF++PFYK  EGKPSNSR+A+TL+DVP  
Sbjct: 804  LNTKYRMLTILNGGGASSCTITGLVQYTLYEFFIVPFYKSVEGKPSNSRIARTLEDVPSE 863

Query: 734  PPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT 793
             P  +E  +LN++ V LKW  PEL+ ++G++  Y+V+V  +D   N S +  N T+  A+
Sbjct: 864  APYGMEALLLNSSAVFLKWKAPELKDRHGVLLNYHVIVRGIDTAHNFSRILTNVTIDAAS 923

Query: 794  -SLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLD--LLSRYPMNGEVSI 850
             +L++ NLT GV Y+V +AA    G+GP+       +D  +  LD  +  RYP+N +   
Sbjct: 924  PTLVLANLTEGVMYTVGVAAGNNAGVGPYCVPATLRLDPITKRLDPFINQRYPINQDH-- 981

Query: 851  VAGDFVMETWFYFLIGAIVLFKIIVIAGIIYVRKYNIFAKKSALPNIYDSNGTSLVTQM 909
               D + + WF  L+GAI+   ++    +++V++ ++  K+SAL N    N TS V +M
Sbjct: 982  -VNDVLTQPWFIILLGAILAVLMLSFGAMVFVKRKHMMMKQSAL-NTMRGNHTSDVLKM 1038


>UniRef50_UPI0000D55AA5 Cluster: PREDICTED: similar to CG13521-PA,
           isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG13521-PA, isoform A - Tribolium castaneum
          Length = 1073

 Score =  675 bits (1667), Expect = 0.0
 Identities = 378/907 (41%), Positives = 523/907 (57%), Gaps = 60/907 (6%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-----THRSILPAGG 65
           +P I E P D+ VA+++P TLNC+A G P P I W+K G  V +      +HR +LPAG 
Sbjct: 18  SPRITEHPSDIIVAKNEPVTLNCKAEGRPEPTIEWFKDGEPVKTSPTDNKSHRVLLPAGS 77

Query: 66  LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
           LFFLR  + +   DAGVYWC A N+ G+A SRNATL VAVLR+EFR+ P   + A G+T 
Sbjct: 78  LFFLRTMNSKKEQDAGVYWCVARNTAGSAVSRNATLQVAVLRDEFRVMPSDTRVAAGETA 137

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
           +L+C  PRG PEPN+ W+K+G+ L  DG  R+ +VDGGNL+I D RQ D GRYQC+A N 
Sbjct: 138 LLQCGAPRGHPEPNLMWRKDGEVLEVDG-RRIRIVDGGNLMISDVRQHDEGRYQCVAHNL 196

Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
            G+RE+    L +H+KP+    P+DVVA  G  V FQC V G+P+P+VLWRR    G MP
Sbjct: 197 VGSRETPPVMLTVHVKPFFNKEPQDVVALLGKRVVFQCAVDGEPVPNVLWRRE--DGKMP 254

Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
           +GR ++LDD SL +DNV  +DEG Y C AEN VG+++A   L V  PP+    P    V 
Sbjct: 255 IGRARILDDKSLLIDNVQTSDEGIYICAAENVVGSITAKASLVVNSPPTFIEKPRDQKVS 314

Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
              V  F C+ATG P P++FW+ EG++ ++FP  S    H  A   G   L I    + D
Sbjct: 315 LNGVVEFHCSATGNPPPSVFWTKEGSQMLMFPDNSYGHMHVNA--HG--TLRIQGVQRED 370

Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
           +   +VCSA++ AGSS VR  L VTS  D PPPII  GP+NQTLP+ SM    C A  +P
Sbjct: 371 A-GFLVCSALSVAGSSSVRAFLQVTSVADLPPPIIQIGPANQTLPLHSMVTLHCKA-SSP 428

Query: 426 E---PIIAWYFEGEALIQNH---RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479
           E   P I W  +G+ L +     R  ++  GTL + DL   DSG YTC A S  G+  WS
Sbjct: 429 EGEQPKIRWSKDGKVLQEERLPDRYTISETGTLDIDDLRLDDSGLYTCSAISESGESSWS 488

Query: 480 GALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQ 539
            +L V    +  +H  R+ D S+ P  P +P   N T++S+TL+W    + G   ++GY 
Sbjct: 489 ASLSVVEGSSALLH--RSPDPSTFPKAPNQPRILNATESSITLAWDDGPEAG---LVGYT 543

Query: 540 VEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
           VE +S         P    GWV+ A RV   + VV+ L P  +YMFIVR EN+HGLS  S
Sbjct: 544 VEYWS---------PDLQTGWVIAAHRV-SNYIVVRELKPDSSYMFIVRAENAHGLSPAS 593

Query: 600 PVSDSVTVGDDSNSLWEGTGVSNS-TEYRNNILTDHIVELIEATPIDSKTIKLMWEILNF 658
           PVS        + +L     VS S  +     L+  +VEL +A P  S ++KL W +   
Sbjct: 594 PVSSI------ARTLANSRAVSGSELDTARTALSTKLVELRDARPQSSSSVKLTWSLAAL 647

Query: 659 YYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKP 718
            Y+EGL+I FR L   +  Y + T+L     S + +++L+K+TKYEFF+ PFYK  EG+P
Sbjct: 648 DYIEGLYIRFRELSGGSHNYNILTVLDVQTKS-YTVSNLKKFTKYEFFIAPFYKSVEGQP 706

Query: 719 SNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPA 778
           SNSRVAQTL+DVP  PP  +   + N T   ++WSPP  Q  NGII GY + +       
Sbjct: 707 SNSRVAQTLEDVPSAPPDGVTAGVFNDTAGWVRWSPPPPQHHNGIIIGYKIQIRG---SI 763

Query: 779 NKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDL 838
            +S+   ++T    TS++++NLTSG SY+ +IAA T  G GP+S +V      R+     
Sbjct: 764 TRSLTVNSST----TSVLISNLTSGGSYNARIAALTHAGQGPYSNQVPLLTAPRAQSPRT 819

Query: 839 LSRYPMNGEVSIVAGDFVMETWFYFLIGAIVLFKIIVIAGIIYVRKYNIFAKKSALPNIY 898
           L  +             V +TWF  L+   +L  +++  G++Y++K    +K+    N+ 
Sbjct: 820 LGPFV----------PLVQQTWFVVLLATAILAILVITGGLLYLKKRQSLSKQLGHLNVP 869

Query: 899 DSNGTSL 905
             N + L
Sbjct: 870 VVNASQL 876



 Score = 36.3 bits (80), Expect = 5.1
 Identities = 28/102 (27%), Positives = 43/102 (42%), Gaps = 9/102 (8%)

Query: 391 SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL------IQNHRR 444
           +D     P IT  PS+  +         C A   PEP I W+ +GE +       ++HR 
Sbjct: 12  NDSQFRSPRITEHPSDIIVAKNEPVTLNCKAEGRPEPTIEWFKDGEPVKTSPTDNKSHRV 71

Query: 445 NVTNDGTLVLKDLD---KSDSGTYTCVASSRHGKYVWSGALL 483
            +       L+ ++   + D+G Y CVA +  G  V   A L
Sbjct: 72  LLPAGSLFFLRTMNSKKEQDAGVYWCVARNTAGSAVSRNATL 113


>UniRef50_Q9W213 Cluster: CG13521-PB, isoform B; n=5;
           Sophophora|Rep: CG13521-PB, isoform B - Drosophila
           melanogaster (Fruit fly)
          Length = 1429

 Score =  634 bits (1566), Expect = e-180
 Identities = 337/838 (40%), Positives = 494/838 (58%), Gaps = 45/838 (5%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD---THRSILPAGGL 66
           ++P IIE P D+ V +++PATLNC+  G P P I W+K G  V ++   +HR     G L
Sbjct: 88  QSPRIIEHPTDLVVKKNEPATLNCKVEGKPEPTIEWFKDGEPVSTNEKKSHRVQFKDGAL 147

Query: 67  FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
           FF R   G+   D G YWC A N  G A SR+A+L +AVLR++FR+EP+  + A+G+T +
Sbjct: 148 FFYRTMQGKKEQDGGEYWCVAKNRVGQAVSRHASLQIAVLRDDFRVEPKDTRVAKGETAL 207

Query: 127 LECLPPRGSPEPNVYWKKNG------QTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
           LEC PP+G PEP + W K+G      + + F   SR+ +VDGGNL+I +    D G Y+C
Sbjct: 208 LECGPPKGIPEPTLIWIKDGVPLDDLKAMSFGASSRVRIVDGGNLLISNVEPIDEGNYKC 267

Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
           IA+N  GTRES+ A L + +KPY +  P+D V   G + TF C VGGDP P VLW++  G
Sbjct: 268 IAQNLVGTRESSYAKLIVQVKPYFMKEPKDQVMLYGQTATFHCSVGGDPPPKVLWKKEEG 327

Query: 241 GGNMPLGRVKVL-DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
             N+P+ R ++L D+ SL + N+   DEG Y CEA N+VG +SA   L V+ PP+    P
Sbjct: 328 --NIPVSRARILHDEKSLEISNITPTDEGTYVCEAHNNVGQISARASLIVHAPPNFTKRP 385

Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
           ++  V    V +  C A+G P P++FW+ EG  T++FP  S  + H  A  DG   L I 
Sbjct: 386 SNKKVGLNGVVQLPCMASGNPPPSVFWTKEGVSTLMFPNSSHGRQHVAA--DGT--LQIT 441

Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419
           D  + D     VCSA +   SS VR  L V+S D+RPPPII  GP+NQTLP  S+A  PC
Sbjct: 442 DVRQEDE-GYYVCSAFSVVDSSTVRVFLQVSSLDERPPPIIQIGPANQTLPKGSVATLPC 500

Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479
            A   P P I W+ +G A+   +R ++    +L + DL  SDSGTYTC AS   G+  W+
Sbjct: 501 RATGNPSPRIKWFHDGHAVQAGNRYSIIQGSSLRVDDLQLSDSGTYTCTASGERGETSWA 560

Query: 480 GALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN-NKIGS-SSILG 537
             L V+ P + ++H  RAAD S+ P PP  P   NV+ TS++L W+++  K G+   I+G
Sbjct: 561 ATLTVEKPGSTSLH--RAADPSTYPAPPGTPKVLNVSRTSISLRWAKSQEKPGAVGPIIG 618

Query: 538 YQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSG 597
           Y VE FS         P    GW+V A+RV  T   +  L PG +Y+F+VR EN+ G+S 
Sbjct: 619 YTVEYFS---------PDLQTGWIVAAQRVGDTQVTISGLTPGTSYVFLVRAENTQGISV 669

Query: 598 PSPVSDSV-TVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEI- 655
           PS +S+++ T+  D ++       +N       +LT   VELI+A+ I++  ++L W + 
Sbjct: 670 PSGLSNTIKTIEADFDA-----ASANDLSAARTLLTGKSVELIDASAINASAVRLEWMLH 724

Query: 656 --LNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKK 713
              +  Y+EGL I+++     + +Y   T++ ++    F + +L+KYTKYEFFL PF++ 
Sbjct: 725 VSADEKYVEGLRIHYKDASVPSAQYHSITVMDAS-AESFVVGNLKKYTKYEFFLTPFFET 783

Query: 714 FEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNW 773
            EG+PSNS+ A T +DVP  PP NI++ + N T   ++W+PP  Q  NG + GY + V+ 
Sbjct: 784 IEGQPSNSKTALTYEDVPSAPPDNIQIGMYNQTAGWVRWTPPPSQHHNGNLYGYKIEVS- 842

Query: 774 LDVPANKSMVAINTTVH-QATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNID 830
                N   V  N T++   TS+++ NLT+G  YSV++ + T  G GP+S+ +   +D
Sbjct: 843 ---AGNTMKVLANMTLNATTTSVLLNNLTTGAVYSVRLNSFTKAGDGPYSKPISLFMD 897



 Score = 50.8 bits (116), Expect = 2e-04
 Identities = 52/208 (25%), Positives = 79/208 (37%), Gaps = 23/208 (11%)

Query: 290 YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
           Y  P I   P  + V+    A   C   G+PEPT+ W  +G         +  K H    
Sbjct: 87  YQSPRIIEHPTDLVVKKNEPATLNCKVEGKPEPTIEWFKDGEPV----STNEKKSHRVQF 142

Query: 350 FDGVTVL--TINDTDKNDSRNTIVCSAVNYAGSSFVRG---KLTVTSDDDRPPPIITNGP 404
            DG      T+    + D      C A N  G +  R    ++ V  DD R  P  T   
Sbjct: 143 KDGALFFYRTMQGKKEQDG-GEYWCVAKNRVGQAVSRHASLQIAVLRDDFRVEPKDTRVA 201

Query: 405 SNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ--------NHRRNVTNDGTLVLKD 456
             +T  ++     P   I  PEP + W  +G  L          + R  + + G L++ +
Sbjct: 202 KGETALLE---CGPPKGI--PEPTLIWIKDGVPLDDLKAMSFGASSRVRIVDGGNLLISN 256

Query: 457 LDKSDSGTYTCVASSRHGKYVWSGALLV 484
           ++  D G Y C+A +  G    S A L+
Sbjct: 257 VEPIDEGNYKCIAQNLVGTRESSYAKLI 284


>UniRef50_Q17BD3 Cluster: Roundabout 1; n=3; Culicidae|Rep:
           Roundabout 1 - Aedes aegypti (Yellowfever mosquito)
          Length = 1231

 Score =  617 bits (1525), Expect = e-175
 Identities = 337/901 (37%), Positives = 502/901 (55%), Gaps = 44/901 (4%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P I E P DV V ++ P TLNC+A G P P IRWYK G  V    +  +LP+G LFFLR 
Sbjct: 51  PRITEHPSDVLVPKNDPVTLNCKAEGKPEPEIRWYKDGEPVKFTPNHVLLPSGSLFFLRT 110

Query: 72  THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
            H +   D GVYWC A+N+ GT  SRNATL +AVLR+EFR+EP+  + A G+T +LEC  
Sbjct: 111 VHSKKEQDGGVYWCVASNAAGTVNSRNATLQIAVLRDEFRVEPKDTRVAAGETALLECGA 170

Query: 132 PRGSPEPNVYWKKNGQTLLFDG----------DSRMHLVDGGNLVIQDARQTDAGRYQCI 181
           P+G+PEP + W+K+   L  D            +R+ +VDGGNL+I D R TD GRYQCI
Sbjct: 171 PKGNPEPTISWRKDEIMLELDDFRPASASGKEPARVRIVDGGNLLISDVRPTDEGRYQCI 230

Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
           A+N  G+RES    L + +KPY I  P D+    G  V FQC VGGDP P +LW++    
Sbjct: 231 AQNMVGSRESGSGKLTVQVKPYFINEPTDITVLVGQRVQFQCTVGGDPHPQILWKKE--N 288

Query: 242 GNMPLGRVKVL-DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
           G++P+GR ++L +D SL + NV   D+G Y CEA NSVG ++A   L V   P+  + P 
Sbjct: 289 GHIPVGRAEILEEDRSLVIKNVAQDDQGIYICEAHNSVGQINAKAQLVVNSSPTFIIKPQ 348

Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
                   VA F CTA+G P P++FW+ EG++T++FP  +    H ++   G   L +  
Sbjct: 349 DQRTNLNGVATFKCTASGNPPPSVFWTKEGSQTLMFPNNTYGNIHISS--QG--SLQVRG 404

Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD-DDRPPPIITNGPSNQTLPIKSMAVFPC 419
             K D     VCSA++ AGS+  R  L VTS  D  PPP++   PSN TLP  S+A+ PC
Sbjct: 405 AQKEDD-GYFVCSALSVAGSTTSRAYLQVTSSFDSSPPPVLQEVPSNLTLPRGSIAMLPC 463

Query: 420 TAICTPEPIIAWYFEG-EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVW 478
                  P I W     +      R ++   GTL + D+   DSG Y+CVA S  G+  W
Sbjct: 464 RGSGPTSPKIYWKKNATDITALGPRFSIVQGGTLKIDDIQPEDSGWYSCVAYSEKGETSW 523

Query: 479 SGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGY 538
           S  L V+  ++  +   R+     LP  P+ P   N+T+++VTL W+   KIG       
Sbjct: 524 SAFLQVEKNLSTMLP--RSGSPELLPVAPSIPKAVNITNSNVTLMWT---KIGGGGEDSL 578

Query: 539 QVEVFSRET---LSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGL 595
           Q ++++      L    +P   +GW + A RV      + +L P  +Y+F+VR EN++G 
Sbjct: 579 QEKLWNNPVSGYLVEYYSPDEKKGW-IRAIRVPGNTATITNLSPSTSYIFVVRAENAYGY 637

Query: 596 SGPSPVSDSV-TVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWE 654
           S PSP+S+ + T+  D     +G  +    E    +L   I+EL++A  I S +++L W+
Sbjct: 638 SAPSPLSNLIRTLSAD-----DGVTMPEELEAARMVLNGKILELVDAVAISSTSVRLEWQ 692

Query: 655 I---LNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFY 711
           +       Y+EGL++ +R L   + +Y M TI  +N      IT+L K+T+YEFFL PF+
Sbjct: 693 LHISSTEEYIEGLYVRYRDLGANSQKYSMLTI-PNNAAEMHVITNLDKFTRYEFFLTPFF 751

Query: 712 KKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVV 771
           K  EG+PSNS+V QT +D P   P+NI+  +LN T   +KWSPP  + QNG++ GY + V
Sbjct: 752 KNVEGQPSNSKVVQTAEDAPTAAPVNIQTGMLNLTAGWVKWSPPPAEHQNGVLLGYKIQV 811

Query: 772 NWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDS 831
              +     + + +N+T    TS+++ NLT+G +Y  QI A   +G GP+S+  Y  +D 
Sbjct: 812 KAGNSSKTLASMTLNST---TTSVMLNNLTTGATYRAQIVAFNRVGAGPYSKPAYLIMDP 868

Query: 832 RSVGLDLLSRYPMNGEVSIVAGDFVMETWF--YFLIGAIVLFKIIVIAGIIYVRKYNIFA 889
             V     +   ++        +F+ ETWF  + ++  +++    V+  +++++K    +
Sbjct: 869 AHVIAPPRAHNSLSDIGGYRHHNFMHETWFMVFVVLALLIILTFTVVGVVVFIKKRQNMS 928

Query: 890 K 890
           K
Sbjct: 929 K 929



 Score = 72.5 bits (170), Expect = 6e-11
 Identities = 63/242 (26%), Positives = 104/242 (42%), Gaps = 17/242 (7%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG---VLVVSDTHRSI-LPAGGL 66
           +P  I +P D     +  AT  C A G+P P++ W K G   ++  ++T+ +I + + G 
Sbjct: 340 SPTFIIKPQDQRTNLNGVATFKCTASGNPPPSVFWTKEGSQTLMFPNNTYGNIHISSQGS 399

Query: 67  FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-----FRLEPESKQSAQ 121
             +R   G    D G + C A +  G+  SR A L V    +       +  P +    +
Sbjct: 400 LQVR---GAQKEDDGYFVCSALSVAGSTTSR-AYLQVTSSFDSSPPPVLQEVPSNLTLPR 455

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
           G   +L C    G   P +YWKKN   +   G  R  +V GG L I D +  D+G Y C+
Sbjct: 456 GSIAMLPC-RGSGPTSPKIYWKKNATDITALG-PRFSIVQGGTLKIDDIQPEDSGWYSCV 513

Query: 182 ARNAAG-TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
           A +  G T  SA   ++ ++   L       +     S+     +    +  ++W +  G
Sbjct: 514 AYSEKGETSWSAFLQVEKNLSTMLPRSGSPELLPVAPSIPKAVNITNSNV-TLMWTKIGG 572

Query: 241 GG 242
           GG
Sbjct: 573 GG 574



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 3/85 (3%)

Query: 8   SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
           S   P + E P ++T+ R   A L CR  G  SP I W K    + +   R  +  GG  
Sbjct: 438 SSPPPVLQEVPSNLTLPRGSIAMLPCRGSGPTSPKIYWKKNATDITALGPRFSIVQGGTL 497

Query: 68  FLRATHGRVHSDAGVYWCEATNSYG 92
            +         D+G Y C A +  G
Sbjct: 498 KIDDIQ---PEDSGWYSCVAYSEKG 519


>UniRef50_Q17BD5 Cluster: Roundabout; n=1; Aedes aegypti|Rep:
           Roundabout - Aedes aegypti (Yellowfever mosquito)
          Length = 1117

 Score =  598 bits (1476), Expect = e-169
 Identities = 346/918 (37%), Positives = 501/918 (54%), Gaps = 57/918 (6%)

Query: 5   YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
           Y     +P I E P DVTV +  P TLNC+A G P P ++W+K G  V  D++  +LPAG
Sbjct: 20  YTAQYRSPRITEHPSDVTVPKGDPVTLNCQAEGKPQPVVQWFKDGDPVKLDSNHVLLPAG 79

Query: 65  GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
            LFFLR  H +   D GVYWC A+N  GT  SRNATL VAVLR++FR+EP++ + A G+T
Sbjct: 80  SLFFLRTLHSKKEQDDGVYWCVASNKAGTVHSRNATLQVAVLRDDFRVEPKNTRVAAGET 139

Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGD------SRMHLVDGGNLVIQDARQTDAGRY 178
            +LEC  PRG+PEP++ WKK+   L  D        +R+ +VD GNL+I D R  DAGRY
Sbjct: 140 ALLECGAPRGNPEPSISWKKDDVLLDLDDYRVSKDLARIRIVDSGNLLISDVRPGDAGRY 199

Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238
           QC+A+N  G+RES  A L + +KPY I  P DV    G+ V FQC VGGDP P VLW  S
Sbjct: 200 QCVAQNMVGSRESTYAKLAVQVKPYFIAKPSDVTVLEGNRVQFQCAVGGDPFPQVLW--S 257

Query: 239 AGGGNMPLGRVKVL-DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
              G++P+GR ++L +D SL + N    D G+Y CEA NSVG +S    L V  PPS  +
Sbjct: 258 KENGHIPVGRAEILEEDRSLVIRNATPDDRGQYICEAHNSVGQISGRANLAVNTPPSFTV 317

Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
            P    V    VA F C A+G P P++FW+ EG++T++FP    +  + +    G   L 
Sbjct: 318 RPQDQRVVPNGVATFRCDASGNPPPSVFWTKEGSQTLMFP----NNTYGSLQISGQGALQ 373

Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD-DDRPPPIITNGPSNQTLPIKSMAV 416
           I    + D     VCSA++ AGS   R  L VTS  D   PP++   P+NQ+LP  S  +
Sbjct: 374 IRGVQRED-EGYYVCSALSVAGSVTSRVYLQVTSSLDSITPPVLQLVPTNQSLPTGSSTI 432

Query: 417 FPCTAICT---------PEPIIAWYFEGEALIQNHRRNVTN--DGTLVLKDLDKSDSGTY 465
            PC    T          +  I W   G  L       +T    G+L + DL   DSG Y
Sbjct: 433 LPCRFPPTSTNGQSNSMDDGRITWERNGFELSPASSTRITQLPAGSLKIDDLQVQDSGWY 492

Query: 466 TCVA--SSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLS 523
            CVA   S      WS  L V+  +  +    R  +   LP  P  P   N+T+++VTL+
Sbjct: 493 RCVARVGSTVASSAWSAYLTVEDNLPTSQQ--RVFNGDLLPSAPGSPKALNITNSNVTLA 550

Query: 524 W---SQN----NKIGSSSILGYQVEVFSRETLSGNNTP----RNSRGWVVIARRVHQTHY 572
           W   S N    +K  SSS L Y +E F  +  S N+ P    +   GW +  R +     
Sbjct: 551 WPIRSTNAPSPDKSRSSS-LTYTIEQFCLDDTSTNSLPTAPSQPDGGWEIALRHLAGNTA 609

Query: 573 VVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV-TVGDDSNSLWEGTGVSNSTEYRNNIL 631
            V  L P  +Y+F+VR EN++G S PS VS  + T+  D     +   V    E   N+L
Sbjct: 610 TVTGLRPDTSYLFVVRAENAYGCSVPSAVSVPIRTLSSD-----DRVTVPAEMESARNVL 664

Query: 632 TDHIVELIEATPIDSKTIKLMWEI---LNFYYLEGLFIYFRPLDNITIEYEMKTILHSND 688
           +  I+ELI+  P+ S +++L W +    +  ++EG ++ +R LD+ T  Y M +I  +N+
Sbjct: 665 SGKILELIDIIPLSSTSVRLEWLLHVSSSEQFVEGFYVRYRELDSPTQRYSMLSI-PNNE 723

Query: 689 VSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTV 748
           +    IT+L K+TKYEFF  PF+K  EG+PSN+R+ QT++D+P   P NI+  +LN T  
Sbjct: 724 IEQHIITNLAKFTKYEFFFTPFFKNLEGQPSNARIVQTMEDLPSIAPGNIQTGMLNLTAG 783

Query: 749 HLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSV 808
            ++WSPP     NG++ GY + V   +V    + + +N T    TS+++ NLT+G SYS+
Sbjct: 784 WVRWSPPPKDQLNGVLQGYKIQVKAGNVSKLLAQMTLNAT---TTSVMLNNLTTGSSYSI 840

Query: 809 QIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETWF--YFLIG 866
           ++ A   +GLGP+S+ V+  +D   V +        N        +F+ ETWF  + ++ 
Sbjct: 841 RVGAFNRVGLGPYSKPVHLTMDPSFVIVPQGVHNSYNDYEDFRHHNFLHETWFMIFVVLS 900

Query: 867 AIVLFKIIVIAGIIYVRK 884
             V+    ++ G+I+ ++
Sbjct: 901 LFVILLFTIVGGVIFFKR 918


>UniRef50_UPI0000DB7FD0 Cluster: PREDICTED: similar to roundabout
           CG13521-PA, isoform A, partial; n=1; Apis mellifera|Rep:
           PREDICTED: similar to roundabout CG13521-PA, isoform A,
           partial - Apis mellifera
          Length = 1389

 Score =  580 bits (1431), Expect = e-163
 Identities = 319/802 (39%), Positives = 466/802 (58%), Gaps = 38/802 (4%)

Query: 100 TLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL 159
           TL V VLR+EFR EP++ + A G+T +LEC PPRG PEP ++WK+NG T+  +   R+ L
Sbjct: 3   TLFVTVLRDEFRAEPQNTRVAAGETALLECGPPRGHPEPTLHWKRNGHTIDLETTKRITL 62

Query: 160 VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSV 219
           VDGGNL+I D RQTD G+YQC+A N  G +ESA+ATL +H+KP+ ++ P +       + 
Sbjct: 63  VDGGNLMISDVRQTDQGKYQCVAENMVGVKESAVATLTVHVKPFFLSTPANQTILADQTA 122

Query: 220 TFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279
            F CRVGGDP P++LWRR+   G MP+GR  +LDD SLR++ V   D+G Y C+AEN VG
Sbjct: 123 EFACRVGGDPPPEILWRRN--DGKMPIGRAHILDDKSLRIERVTSQDQGTYICDAENGVG 180

Query: 280 AVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGM 339
           A+SAS  LTV+  P  +  P    V  G+   F+C A G P+P++FW+ EG++ ++FPG 
Sbjct: 181 AISASATLTVHSRPVFSSFPKDEIVSVGSNVSFSCAARGAPKPSIFWTREGSQELMFPGN 240

Query: 340 S-RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398
             + +Y  T   DG   L I      D  +  VCSA++ AG+S     L VTS ++ PPP
Sbjct: 241 EYQSRYKITD--DG--SLHIKGVLGKDEGH-YVCSAISQAGASTATVFLQVTSVEEVPPP 295

Query: 399 IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE--ALIQNHRRNVTNDGTLVLKD 456
           +I  GP+NQTLP KS    PC     P P I WY E E   +  +++  + ++GTL +K+
Sbjct: 296 VIEIGPTNQTLPPKSDISMPCRVFGRPTPKIRWYKEDELVRIGSDNKFTIASNGTLSIKN 355

Query: 457 LDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVT 516
           L  SDSG Y CVASS  G   W  +L + SP   N H     DVS+LP  P+KP   N T
Sbjct: 356 LQLSDSGIYKCVASSESGNTSWIASLTI-SP-GANYHSI-IPDVSALPENPSKPRIVNTT 412

Query: 517 DTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKS 576
            ++VTL+WS  ++ G+S I+ Y VE F+         P+ S  W+V    +    Y V +
Sbjct: 413 SSTVTLTWSPGHE-GASKIIDYTVEYFA-------TNPKTS--WIVAGTEITDDIYTVTN 462

Query: 577 LIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIV 636
           L P  +Y+F+VR  N+ GLS P P SD   V   +N        +     R+  L   I+
Sbjct: 463 LTPDTSYVFLVRARNNQGLSVPGPFSD---VARTTNLDQHAIPQTELIRARDR-LNSEIL 518

Query: 637 ELIEATPIDSKTIKLMWEILNFYYL-EGLFIYFRPLDNITIEYEMKTILHSNDVSGFEIT 695
            L +  P+ S ++K++W+IL    L EGL+I +R +     EY M T+L++   S + +T
Sbjct: 519 YLKDVQPLSSTSVKIVWDILGAADLVEGLYIRYREVSE-KPEYRMVTVLNAGATS-YVLT 576

Query: 696 SLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPP 755
           +L KYT+YEFFL+PF+K  EG+PSN ++A TL+D+P G P N+ + ++N T+  ++WSPP
Sbjct: 577 NLNKYTRYEFFLVPFFKTIEGRPSNVKLATTLEDIPSGAPENVHVGMINITSAFVRWSPP 636

Query: 756 ELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETI 815
               QNG + GY + +      +NK +  ++      TS+I+ +LT+G  Y+ ++A  T 
Sbjct: 637 PKSTQNGQLLGYKIQIK--SNSSNKILGQMSLNA-STTSVIINSLTTGGLYTARVAGYTR 693

Query: 816 IGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETWFYFLIGAIVLFKIIV 875
           +G GPFS     N+D        L++ P   + S      V ETWF  L+  +VL  I  
Sbjct: 694 VGQGPFSNPTILNMDPGQ-----LTQLPPRTDPSQRNASVVSETWFLILMITVVLTVIAA 748

Query: 876 IAGIIYVRKYNIFAKKSALPNI 897
           + G +YVR+    +K+    N+
Sbjct: 749 LLGAVYVRRRQAMSKQLGHLNV 770



 Score =  149 bits (362), Expect = 3e-34
 Identities = 101/325 (31%), Positives = 141/325 (43%), Gaps = 21/325 (6%)

Query: 17  QPLDVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHG 74
           +P +  VA  + A L C    G P P + W + G  + +  T R  L  GG   +     
Sbjct: 16  EPQNTRVAAGETALLECGPPRGHPEPTLHWKRNGHTIDLETTKRITLVDGGNLMISDVR- 74

Query: 75  RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRG 134
              +D G Y C A N  G   S  ATL V V  + F L   + Q+   D          G
Sbjct: 75  --QTDQGKYQCVAENMVGVKESAVATLTVHV--KPFFLSTPANQTILADQTAEFACRVGG 130

Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194
            P P + W++N   +      R H++D  +L I+     D G Y C A N  G   SA A
Sbjct: 131 DPPPEILWRRNDGKMPI---GRAHILDDKSLRIERVTSQDQGTYICDAENGVGA-ISASA 186

Query: 195 TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG-----GGNMPLGRV 249
           TL +H +P   + P+D +   GS+V+F C   G P P + W R         GN    R 
Sbjct: 187 TLTVHSRPVFSSFPKDEIVSVGSNVSFSCAARGAPKPSIFWTREGSQELMFPGNEYQSRY 246

Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV-----YDPPSINLSPNSVNV 304
           K+ DDGSL +  V+  DEG Y C A +  GA +A+ +L V       PP I + P +  +
Sbjct: 247 KITDDGSLHIKGVLGKDEGHYVCSAISQAGASTATVFLQVTSVEEVPPPVIEIGPTNQTL 306

Query: 305 ESGNVARFTCTATGRPEPTMFWSVE 329
              +     C   GRP P + W  E
Sbjct: 307 PPKSDISMPCRVFGRPTPKIRWYKE 331



 Score =  118 bits (284), Expect = 1e-24
 Identities = 92/326 (28%), Positives = 142/326 (43%), Gaps = 19/326 (5%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAGGLFFLR 70
           P+ +  P + T+   Q A   CR GG P P I W +  G + +   H  IL    L   R
Sbjct: 105 PFFLSTPANQTILADQTAEFACRVGGDPPPEILWRRNDGKMPIGRAH--ILDDKSLRIER 162

Query: 71  ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
            T      D G Y C+A N  G A S +ATL V   R  F   P+ +  + G  V   C 
Sbjct: 163 VT----SQDQGTYICDAENGVG-AISASATLTVH-SRPVFSSFPKDEIVSVGSNVSFSC- 215

Query: 131 PPRGSPEPNVYWKKNG-QTLLFDGD---SRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
             RG+P+P+++W + G Q L+F G+   SR  + D G+L I+     D G Y C A + A
Sbjct: 216 AARGAPKPSIFWTREGSQELMFPGNEYQSRYKITDDGSLHIKGVLGKDEGHYVCSAISQA 275

Query: 187 GTRESAIATLKIHIK----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
           G   + +      ++    P +  GP +      S ++  CRV G P P + W +     
Sbjct: 276 GASTATVFLQVTSVEEVPPPVIEIGPTNQTLPPKSDISMPCRVFGRPTPKIRWYKEDELV 335

Query: 243 NMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
            +    +  +  +G+L + N+ L+D G Y C A +  G  S    LT+    + +     
Sbjct: 336 RIGSDNKFTIASNGTLSIKNLQLSDSGIYKCVASSESGNTSWIASLTISPGANYHSIIPD 395

Query: 302 VNVESGNVARFTCTATGRPEPTMFWS 327
           V+    N ++     T     T+ WS
Sbjct: 396 VSALPENPSKPRIVNTTSSTVTLTWS 421



 Score = 57.2 bits (132), Expect = 3e-06
 Identities = 48/202 (23%), Positives = 88/202 (43%), Gaps = 15/202 (7%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG---VLVVSDTHRS--I 60
           +T    P     P D  V+     + +C A G+P P+I W + G   ++   + ++S   
Sbjct: 188 LTVHSRPVFSSFPKDEIVSVGSNVSFSCAARGAPKPSIFWTREGSQELMFPGNEYQSRYK 247

Query: 61  LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE----EFRLEPES 116
           +   G   ++   G+   D G Y C A +  G A +    L V  + E       + P +
Sbjct: 248 ITDDGSLHIKGVLGK---DEGHYVCSAISQAG-ASTATVFLQVTSVEEVPPPVIEIGPTN 303

Query: 117 KQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAG 176
           +       + + C    G P P + W K  + +    D++  +   G L I++ + +D+G
Sbjct: 304 QTLPPKSDISMPC-RVFGRPTPKIRWYKEDELVRIGSDNKFTIASNGTLSIKNLQLSDSG 362

Query: 177 RYQCIARNAAGTRESAIATLKI 198
            Y+C+A + +G   S IA+L I
Sbjct: 363 IYKCVASSESG-NTSWIASLTI 383


>UniRef50_Q98SW3 Cluster: Transmembrane receptor Roundabout3; n=23;
           Euteleostomi|Rep: Transmembrane receptor Roundabout3 -
           Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 1419

 Score =  528 bits (1304), Expect = e-148
 Identities = 308/829 (37%), Positives = 446/829 (53%), Gaps = 44/829 (5%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-----THRSILPAGG 65
           AP I+E P D+ V++ +PATLNC+A G P+P + WYK G  V +D     +HR +LP+G 
Sbjct: 62  APRIVEHPSDLIVSKGEPATLNCKAEGRPTPMVEWYKDGERVETDREDPRSHRMLLPSGS 121

Query: 66  LFFLRATHGRVHS-DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
           LFFLR  HGR    D GVY C A N  G A SRNA+L VA+LR++FR  P     A G+ 
Sbjct: 122 LFFLRIVHGRRSKPDEGVYVCVARNYLGEAVSRNASLEVAILRDDFRQTPSDVVVAAGEP 181

Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
            V+EC+PPRG PEP + WK+N    + D D R+  + GG L+I + R++DAG Y C+  N
Sbjct: 182 AVMECIPPRGHPEPTISWKRNN-VKVNDKDERI-TIRGGKLMISNTRKSDAGMYVCVGTN 239

Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
             G ++S  A L +  +P  +  P + V     +V FQC V GDP P + W++  G   +
Sbjct: 240 MVGEKDSDPAELVVFERPMFVRRPVNQVVLADDTVDFQCEVQGDPAPTIRWKKEEG--EL 297

Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
           P GR ++  D SLRL  V   DEG Y+C +ENSVG   ASG L V+ PP I + P     
Sbjct: 298 PRGRFEIRADNSLRLTQVKAEDEGSYTCLSENSVGKAEASGSLQVHVPPQIVVRPRDQIS 357

Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV-FDGVTVLTINDTDK 363
             G    F C   G P P +FW  EG++ ++FP     +    +V   G   LTI D   
Sbjct: 358 AQGRTVTFLCGTKGNPPPAVFWQKEGSQVLLFPSQPPSQSGRFSVSLSG--ELTITDVHS 415

Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTS-DDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
            DS    +C A++ AGS   +  L V S   DR PPII  GP+NQTL   + A   C  +
Sbjct: 416 EDS-GYYICQAISVAGSILTKALLEVESTPSDRIPPIIRQGPANQTLAPGTTAQLQCHVM 474

Query: 423 CTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
             P P I W  +G+ ++  + R ++  +GTL +  L ++DSG YTCVASS  G+  WSG 
Sbjct: 475 GNPLPSIQWERDGQRILGIDERISLMENGTLQITALQETDSGAYTCVASSLSGETSWSGV 534

Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541
           L V    +  +     ++   LPGPP KP+  +VT  SVTL+W  N   G +++  Y +E
Sbjct: 535 LTVKE--SGGLSASPVSEPYQLPGPPQKPVVTDVTRNSVTLTWQPNAHEGGAAVTSYIIE 592

Query: 542 VFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPV 601
            FS+   S  +T      W  +A  V    + V  L P   Y+FIVR  N++GLS PSP+
Sbjct: 593 AFSQ---SAGST------WQTVADFVKLEKHTVTGLSPNTIYLFIVRAVNAYGLSDPSPI 643

Query: 602 SDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEI-LNFYY 660
           S+ V   D S +   G GV +    R   L +  V+L E   + + ++K+ W +     Y
Sbjct: 644 SEPVRTQDVSPT---GQGVDHRQVQRE--LGEMSVQLHEPVLLTASSVKISWNVDRQSQY 698

Query: 661 LEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN 720
           ++G  + +RP+     + E+K     + V    I +L K T+YE  + P++ +F+G  S 
Sbjct: 699 IQGYRLLYRPVGGSWSQQEVKGATERSAV----IANLLKGTEYEIKIRPYFNEFQGLDSR 754

Query: 721 SRVAQTLDDVPDGPP--INIEMFIL-NTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVP 777
           S+  +T ++VP  PP  +N+    L N++++ + W PP   +QNG+I  Y V   W    
Sbjct: 755 SQTLRTPEEVPSAPPRAVNVATVKLSNSSSISVSWQPPPTDMQNGVIQEYKV---WCLGN 811

Query: 778 ANKSMVAINTTVH-QATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
            +++   IN TV     S ++  L  GV Y V++AA T  G+G  SQ V
Sbjct: 812 DSQTRYNINQTVDGSVLSTVLKGLLPGVLYQVEVAAVTSAGVGKHSQPV 860



 Score =  124 bits (300), Expect = 1e-26
 Identities = 100/332 (30%), Positives = 147/332 (44%), Gaps = 26/332 (7%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
           E P  + +P++  V         C   G P+P IRW K       +  R          L
Sbjct: 255 ERPMFVRRPVNQVVLADDTVDFQCEVQGDPAPTIRWKK----EEGELPRGRFEIRADNSL 310

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
           R T  +   D G Y C + NS G A + + +L V V   +  + P  + SAQG TV   C
Sbjct: 311 RLTQVKA-EDEGSYTCLSENSVGKAEA-SGSLQVHV-PPQIVVRPRDQISAQGRTVTFLC 367

Query: 130 LPPRGSPEPNVYWKKNG-QTLLFDG-----DSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
              +G+P P V+W+K G Q LLF         R  +   G L I D    D+G Y C A 
Sbjct: 368 -GTKGNPPPAVFWQKEGSQVLLFPSQPPSQSGRFSVSLSGELTITDVHSEDSGYYICQAI 426

Query: 184 NAAGT-RESAI----ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238
           + AG+    A+    +T    I P +  GP +     G++   QC V G+PLP + W R 
Sbjct: 427 SVAGSILTKALLEVESTPSDRIPPIIRQGPANQTLAPGTTAQLQCHVMGNPLPSIQWERD 486

Query: 239 AGGGNMPLG---RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295
              G   LG   R+ ++++G+L++  +   D G Y+C A +  G  S SG LTV +   +
Sbjct: 487 ---GQRILGIDERISLMENGTLQITALQETDSGAYTCVASSLSGETSWSGVLTVKESGGL 543

Query: 296 NLSPNSVNVE-SGNVARFTCTATGRPEPTMFW 326
           + SP S   +  G   +   T   R   T+ W
Sbjct: 544 SASPVSEPYQLPGPPQKPVVTDVTRNSVTLTW 575


>UniRef50_Q9HCK4 Cluster: Roundabout homolog 2 precursor; n=45;
           Euteleostomi|Rep: Roundabout homolog 2 precursor - Homo
           sapiens (Human)
          Length = 1378

 Score =  508 bits (1253), Expect = e-142
 Identities = 300/827 (36%), Positives = 434/827 (52%), Gaps = 45/827 (5%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-----THRSILPAGGL 66
           P I+E P DV V++ +P TLNC+A G P+P I WYK G  V +D     +HR +LP+G L
Sbjct: 31  PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSL 90

Query: 67  FFLRATHGRVHS-DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
           FFLR  HGR    D G Y C A N  G A SRNA+L VA+LR++FR  P     A G+  
Sbjct: 91  FFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPA 150

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
           +LEC PPRG PEP +YWKK+ +  + D + R+  + GG L+I + R++DAG Y C+  N 
Sbjct: 151 ILECQPPRGHPEPTIYWKKD-KVRIDDKEERIS-IRGGKLMISNTRKSDAGMYTCVGTNM 208

Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
            G R+S  A L +  +P  +  P + V     +V F+C+V GDP P V W++     ++P
Sbjct: 209 VGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKD--DADLP 266

Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
            GR  + DD +LR+   +  DEG Y C AEN VG + AS  LTV  PP   + P    V 
Sbjct: 267 RGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVA 326

Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
            G    F C   G P+P +FW  EG++ ++FP   +      +V      LTI +  ++D
Sbjct: 327 QGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSV-SPTGDLTITNIQRSD 385

Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSD-DDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
           +    +C A+  AGS   + +L VT    DRPPPII  GP+NQTL +   A+  C A   
Sbjct: 386 A-GYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGD 444

Query: 425 PEPIIAWYFEGEALI-QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
           P P+I+W  EG     ++ R  +   GTL +K+L  SD+GTYTCVA+S  G+  WS  L 
Sbjct: 445 PLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLD 504

Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543
           V           +  D+S LPGPP+KP   +VT  SVTLSW Q    G+     Y +E F
Sbjct: 505 V---TESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSW-QPGTPGTLPASAYIIEAF 560

Query: 544 SRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
           S+           S  W  +A  V  T Y V+ L P   Y+F+VR  N  GLS PSP+SD
Sbjct: 561 SQSV---------SNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSD 611

Query: 604 SVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEI-LNFYYLE 662
            V   D S       GV +    +   L D +V L     +   T+++ W +     +++
Sbjct: 612 PVRTQDISP---PAQGVDHRQVQKE--LGDVLVRLHNPVVLTPTTVQVTWTVDRQPQFIQ 666

Query: 663 GLFIYFRPLDNI--TIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN 720
           G  + +R    +  T  ++        + S   + +L+K   YE  + P++ +F+G  S 
Sbjct: 667 GYRVMYRQTSGLQATSSWQNLDAKVPTERSAV-LVNLKKGVTYEIKVRPYFNEFQGMDSE 725

Query: 721 SRVAQTLDDVPDGPPINIEMFIL---NTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVP 777
           S+  +T ++ P  PP ++ +  +   N+T++ + W PP    QNGII  Y +   W    
Sbjct: 726 SKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKI---W--CL 780

Query: 778 ANKSMVAINTTVHQA-TSLIMTNLTSGVSYSVQIAAETIIGLGPFSQ 823
            N++   IN TV  A  S+I+  L  G+ Y V++AA T  G+G  S+
Sbjct: 781 GNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSE 827



 Score =  120 bits (288), Expect = 3e-25
 Identities = 85/295 (28%), Positives = 134/295 (45%), Gaps = 19/295 (6%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
           +T  E P  + +P++  V   +     C+  G P P +RW K      +D  R       
Sbjct: 219 LTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDD----ADLPRGRYDIKD 274

Query: 66  LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
            + LR     + +D G Y C A N  G   + +ATL V     +F + P  +  AQG TV
Sbjct: 275 DYTLRIKK-TMSTDEGTYMCIAENRVGKMEA-SATLTVRA-PPQFVVRPRDQIVAQGRTV 331

Query: 126 VLECLPPRGSPEPNVYWKKNG-QTLLFDG-----DSRMHLVDGGNLVIQDARQTDAGRYQ 179
              C   +G+P+P V+W+K G Q LLF       +SR  +   G+L I + +++DAG Y 
Sbjct: 332 TFPC-ETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYI 390

Query: 180 CIARNAAGT-----RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL 234
           C A   AG+     +      L     P ++ GP +       +   +C+  GDPLP + 
Sbjct: 391 CQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVIS 450

Query: 235 WRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
           W +          R  + + G+L++ N+ ++D G Y+C A +S G  S S  L V
Sbjct: 451 WLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDV 505



 Score = 61.7 bits (143), Expect = 1e-07
 Identities = 49/190 (25%), Positives = 76/190 (40%), Gaps = 14/190 (7%)

Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
           PP I   P+ V V  G      C A GRP PT+ W  +G R  +       + H   +  
Sbjct: 30  PPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGER--VETDKDDPRSHRMLLPS 87

Query: 352 G--VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG---KLTVTSDDDRPPPIITNGPSN 406
           G    +  ++         + VC A NY G +  R    ++ +  DD R        P++
Sbjct: 88  GSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFR------QNPTD 141

Query: 407 QTLPIKSMAVFPC-TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465
             +     A+  C      PEP I W  +   +     R     G L++ +  KSD+G Y
Sbjct: 142 VVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMY 201

Query: 466 TCVASSRHGK 475
           TCV ++  G+
Sbjct: 202 TCVGTNMVGE 211



 Score = 50.8 bits (116), Expect = 2e-04
 Identities = 35/100 (35%), Positives = 48/100 (48%), Gaps = 4/100 (4%)

Query: 4   DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
           D +T    P I++ P + T+A    A L C+A G P P I W K G        R+ +  
Sbjct: 410 DVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQE 469

Query: 64  GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103
            G   L+  + R+ SD G Y C AT+S G   S +A L V
Sbjct: 470 QGT--LQIKNLRI-SDTGTYTCVATSSSGET-SWSAVLDV 505


>UniRef50_O44928 Cluster: SAX-3; n=3; Caenorhabditis|Rep: SAX-3 -
            Caenorhabditis elegans
          Length = 1273

 Score =  506 bits (1248), Expect = e-141
 Identities = 333/1034 (32%), Positives = 510/1034 (49%), Gaps = 72/1034 (6%)

Query: 8    SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSD-----THRSIL 61
            S  AP IIE P+DV V+R  PATLNC  G  PS A I WYK G  V+++     +HR +L
Sbjct: 27   SNLAPVIIEHPIDVVVSRGSPATLNC--GAKPSTAKITWYKDGQPVITNKEQVNSHRIVL 84

Query: 62   PAGGLFFLRATHGR--VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS 119
              G LF L+   G+    SDAG Y+C A+N +G  +S   +L +A+LRE+FR+ P + Q+
Sbjct: 85   DTGSLFLLKVNSGKNGKDSDAGAYYCVASNEHGEVKSNEGSLKLAMLREDFRVRPRTVQA 144

Query: 120  AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179
              G+  VLEC PPRG PEP V W+K+ + L      R  L   GNL+I    ++D+G YQ
Sbjct: 145  LGGEMAVLECSPPRGFPEPVVSWRKDDKELRIQDMPRYTLHSDGNLIIDPVDRSDSGTYQ 204

Query: 180  CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
            C+A N  G R S  A L +  KP     P+D+    G++V F CRV GDP P + W+R  
Sbjct: 205  CVANNMVGERVSNPARLSVFEKPKFEQEPKDMTVDVGAAVLFDCRVTGDPQPQITWKRK- 263

Query: 240  GGGNMPLGRVKVL-DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
                MP+ R  +  D+  LR++ V  +DEGEY C A N  G + AS +L V  PPS    
Sbjct: 264  -NEPMPVTRAYIAKDNRGLRIERVQPSDEGEYVCYARNPAGTLEASAHLRVQAPPSFQTK 322

Query: 299  PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPG-MSRDKYHATAVFDGVTVLT 357
            P   +V +G  A F CT  G+P P  FWS EG + ++FP  +S D     +    +T+  
Sbjct: 323  PADQSVPAGGTATFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGTLTIEE 382

Query: 358  INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT------SDDDRPPPIITNGPSNQTLPI 411
            +   D+       VC+ +N AGSS  +  L VT      +   +PPP I +G  NQTL +
Sbjct: 383  VRQVDE----GAYVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQTLMV 438

Query: 412  KSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470
             S A+ PC A   P P I+W  +G  + I + R +  + G+L + DL K D+G YTC+A 
Sbjct: 439  GSSAILPCQASGKPTPGISWLRDGLPIDITDSRISQHSTGSLHIADLKKPDTGVYTCIAK 498

Query: 471  SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530
            +  G+  WS +L V+   + N  F R  D S+ P  PT+PI  NVTDT V L W+  +  
Sbjct: 499  NEDGESTWSASLTVEDHTS-NAQFVRMPDPSNFPSSPTQPIIVNVTDTEVELHWNAPSTS 557

Query: 531  GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590
            G+  I GY ++ +S         P   + W  I   V  T Y +K L P  +YMF++R E
Sbjct: 558  GAGPITGYIIQYYS---------PDLGQTWFNIPDYVASTEYRIKGLKPSHSYMFVIRAE 608

Query: 591  NSHGLSGPSPVSDSVTVGDDSNSL-WEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTI 649
            N  G+  PS  S  VT    +  +        +       + ++ +++L E   I+S  +
Sbjct: 609  NEKGIGTPSVSSALVTTSKPAAQVALSDKNKMDMAIAEKRLTSEQLIKLEEVKTINSTAV 668

Query: 650  KLMWEILNFYYL-EGLFIYFR-PLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFL 707
            +L W+      L +G +I +R P      +Y   T   S     + +++L  +T YEFF+
Sbjct: 669  RLFWKKRKLEELIDGYYIKWRGPPRTNDNQYVNVT---SPSTENYVVSNLMPFTNYEFFV 725

Query: 708  IPFYK---KFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGII 764
            IP++       G PSNS    T +  P  PP ++ + +LN TT+ + W  P+    NGI+
Sbjct: 726  IPYHSGVHSIHGAPSNSMDVLTAEAPPSLPPEDVRIRMLNLTTLRISWKAPKADGINGIL 785

Query: 765  TGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETI--IGLGPFS 822
             G+ +V+     P N   +   TT  +A S+ + +L +G++Y +++AA +   +G+   +
Sbjct: 786  KGFQIVIVG-QAPNNNRNI---TTNERAASVTLFHLVTGMTYKIRVAARSNGGVGVSHGT 841

Query: 823  QKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETWFYFLIGAIVLFKIIVIAGIIYV 882
             +V  N D+    L+         E  +             ++  +++F +I+IA   + 
Sbjct: 842  SEVIMNQDT----LEKHLAAQQENESFLYGLINKSHVPVIVIVAILIIFVVIIIAYCYWR 897

Query: 883  RKYNIFAKKSALPNIYDSNGTSLVTQMNIKAAVSLSHPLTSCYNKNTVTKTESLLWMENQ 942
               N   K  +   I D  G+  +   N+       +P     N+N +  T   + M N+
Sbjct: 898  NSRNSDGKDRSFIKIND--GSVHMASNNLWDVA--QNP-----NQNPMYNTAGRMTMNNR 948

Query: 943  PGVCL-SGNQTSQSKEKTNFEYDKVTHQLP-----EYAEVTSARANEWNT---NKTATSP 993
             G  L S    +Q       +Y    H+        YA++T    N  +T   N+    P
Sbjct: 949  NGQALYSLTPNAQDFFNNCDDYSGTMHRPGSEHHYHYAQLTGGPGNAMSTFYGNQYHDDP 1008

Query: 994  AAYASVTLVANTRQ 1007
            + YA+ TLV + +Q
Sbjct: 1009 SPYATTTLVLSNQQ 1022


>UniRef50_Q9Y6N7 Cluster: Roundabout homolog 1 precursor; n=74;
           Coelomata|Rep: Roundabout homolog 1 precursor - Homo
           sapiens (Human)
          Length = 1651

 Score =  500 bits (1232), Expect = e-139
 Identities = 308/893 (34%), Positives = 458/893 (51%), Gaps = 64/893 (7%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-----THRSILPAGGL 66
           P I+E P D+ V++ +PATLNC+A G P+P I WYKGG  V +D     +HR +LP+G L
Sbjct: 68  PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 127

Query: 67  FFLRATHGRV-HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
           FFLR  HGR    D GVY C A N  G A S NA+L VA+LR++FR  P     A G+  
Sbjct: 128 FFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPA 187

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
           V+EC PPRG PEP + WKK+G  L  D D R+  + GG L+I   R++DAG+Y C+  N 
Sbjct: 188 VMECQPPRGHPEPTISWKKDGSPL-DDKDERI-TIRGGKLMITYTRKSDAGKYVCVGTNM 245

Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
            G RES +A L +  +P  +  P ++      S  F+C   GDP+P V WR+    G +P
Sbjct: 246 VGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKD--DGELP 303

Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
             R ++ DD +L++  V   D G Y+C AEN VG   AS  LTV +PP   + P    V 
Sbjct: 304 KSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPRDQVVA 363

Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIF---PGMSRDKYHATAVFDGVTVLTINDTD 362
            G    F C ATG P+P +FW  EG++ ++F   P  S  ++  +   D    LTI +  
Sbjct: 364 LGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGD----LTITNVQ 419

Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTS-DDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
           ++D     +C  +N AGS   +  L VT    DRPPP+I  GP NQT+ +    V  C A
Sbjct: 420 RSDV-GYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVA 478

Query: 422 ICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
             +P P I W  +G  +  Q+ R     +G L ++     D+G YTC+AS+  G+  WS 
Sbjct: 479 TGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSA 538

Query: 481 ALLVDS---PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILG 537
            + V     P+ P     R  D + +P  P+KP   +V+  +VTLSW  N   G++    
Sbjct: 539 YIEVQEFGVPVQPP----RPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATP-TS 593

Query: 538 YQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSG 597
           Y +E FS    SG++       W  +A  V      +K L P   Y+F+VR  N++G+S 
Sbjct: 594 YIIEAFSH--ASGSS-------WQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISD 644

Query: 598 PSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEI-L 656
           PS +SD V   D    L    GV +    R   L + ++ L   T + S +I++ W +  
Sbjct: 645 PSQISDPVKTQD---VLPTSQGVDHKQVQRE--LGNAVLHLHNPTVLSSSSIEVHWTVDQ 699

Query: 657 NFYYLEGLFIYFRPL-----DNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFY 711
              Y++G  I +RP      ++  + +E++T   ++ V    I  LRK   YE    PF+
Sbjct: 700 QSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKNSVV----IPDLRKGVNYEIKARPFF 755

Query: 712 KKFEGKPSNSRVAQTLDDVPDGPP--INIEMFILNTTTVHLKWSPPELQLQNGIITGYNV 769
            +F+G  S  + A+TL++ P  PP  + +     N T + + W PP    QNG++  Y V
Sbjct: 756 NEFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYKV 815

Query: 770 VVNWLDVPANKSMVAINTTVHQAT-SLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFN 828
              W     N++   IN TV  +T S+++  L  G+ YSV++AA T  G G  S+  +  
Sbjct: 816 ---W--CLGNETRYHINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSEPQFIQ 870

Query: 829 IDSRSVGLDLLSRYPMNGEVSIVAGDFVMETWFYFLIGAIVLFKIIVIAGIIY 881
           +D+    +    +  +  ++S    D V +  F   IGA     ++V +  +Y
Sbjct: 871 LDAHGNPVSPEDQVSLAQQIS----DVVKQPAFIAGIGAACWIILMVFSIWLY 919



 Score =  115 bits (277), Expect = 7e-24
 Identities = 98/333 (29%), Positives = 148/333 (44%), Gaps = 31/333 (9%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFF 68
           E P  +++P ++ V     A   C A G P P +RW K  G L  S     I     L  
Sbjct: 260 ERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS--RYEIRDDHTLKI 317

Query: 69  LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
            + T G    D G Y C A N  G A + +ATL V      F ++P  +  A G TV  +
Sbjct: 318 RKVTAG----DMGSYTCVAENMVGKAEA-SATLTVQE-PPHFVVKPRDQVVALGRTVTFQ 371

Query: 129 CLPPRGSPEPNVYWKKNG-QTLLF-----DGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
           C    G+P+P ++W++ G Q LLF        SR  +   G+L I + +++D G Y C  
Sbjct: 372 C-EATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQT 430

Query: 183 RNAAG---TRESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
            N AG   T+     T  I  +  P +  GP +       +    C   G P+P +LWR+
Sbjct: 431 LNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRK 490

Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD------ 291
                +    R+K L++G L++    L D G Y+C A    G  + S Y+ V +      
Sbjct: 491 DGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQ 550

Query: 292 ---PPSINLSPNSVN-VESGNVARFTCTATGRP 320
              P   NL P++ +  E  +V+R T T + +P
Sbjct: 551 PPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQP 583



 Score = 79.4 bits (187), Expect = 6e-13
 Identities = 62/195 (31%), Positives = 91/195 (46%), Gaps = 20/195 (10%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV--------SDTH 57
           +T  E P+ + +P D  VA  +  T  C A G+P PAI W + G   +        S + 
Sbjct: 345 LTVQEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSR 404

Query: 58  RSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA-VLREE----FRL 112
            S+   G L           SD G Y C+  N  G+  ++ A L V  V+ +      R 
Sbjct: 405 FSVSQTGDLTITNVQ----RSDVGYYICQTLNVAGSIITK-AYLEVTDVIADRPPPVIRQ 459

Query: 113 EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ 172
            P ++  A   T VL C+   GSP P + W+K+G  L+   DSR+  ++ G L I+ A+ 
Sbjct: 460 GPVNQTVAVDGTFVLSCV-ATGSPVPTILWRKDG-VLVSTQDSRIKQLENGVLQIRYAKL 517

Query: 173 TDAGRYQCIARNAAG 187
            D GRY CIA   +G
Sbjct: 518 GDTGRYTCIASTPSG 532



 Score = 64.5 bits (150), Expect = 2e-08
 Identities = 51/190 (26%), Positives = 75/190 (39%), Gaps = 14/190 (7%)

Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
           PP I   P+ + V  G  A   C A GRP PT+ W   G R  +       + H   +  
Sbjct: 67  PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGER--VETDKDDPRSHRMLLPS 124

Query: 352 G--VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG---KLTVTSDDDRPPPIITNGPSN 406
           G    +  ++           VC A NY G +       ++ +  DD R        PS+
Sbjct: 125 GSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFR------QNPSD 178

Query: 407 QTLPIKSMAVFPC-TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465
             + +   AV  C      PEP I+W  +G  L     R     G L++    KSD+G Y
Sbjct: 179 VMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKY 238

Query: 466 TCVASSRHGK 475
            CV ++  G+
Sbjct: 239 VCVGTNMVGE 248



 Score = 46.0 bits (104), Expect = 0.006
 Identities = 31/91 (34%), Positives = 43/91 (47%), Gaps = 3/91 (3%)

Query: 4   DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
           D +     P I + P++ TVA      L+C A GSP P I W K GVLV +   R     
Sbjct: 447 DVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLE 506

Query: 64  GGLFFLRATHGRVHSDAGVYWCEATNSYGTA 94
            G+  +R  + ++  D G Y C A+   G A
Sbjct: 507 NGVLQIR--YAKL-GDTGRYTCIASTPSGEA 534


>UniRef50_Q4RRT1 Cluster: Chromosome 16 SCAF15002, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 16
           SCAF15002, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 1098

 Score =  444 bits (1094), Expect = e-123
 Identities = 259/650 (39%), Positives = 345/650 (53%), Gaps = 30/650 (4%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-----THRSILPAGGL 66
           P I E P D+ V++ +PATLNC+A G P+P I WYK G  V +D     +HR +LP+G L
Sbjct: 17  PRIAEDPSDLIVSKGEPATLNCKAEGRPTPIIEWYKDGERVETDRDDPRSHRMLLPSGSL 76

Query: 67  FFLRATHGRVHS-DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
           FFLR  HGR    D GVY C A N  G A SRNA+L VA+LR++FR  P     A G+  
Sbjct: 77  FFLRIVHGRRSKPDEGVYTCVARNYLGEAVSRNASLDVAILRDDFRQAPSDVVVAAGEPA 136

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
           VLEC+PPRG PEP V+WK+N    +   D R+ +  GG L+I  AR++DAG Y C+ +N 
Sbjct: 137 VLECVPPRGHPEPIVFWKRNN-VRIGSKDDRIAM-RGGKLMISHARKSDAGMYVCVGKNM 194

Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
            G R+S  A L ++ +P L+  P + V     +V FQC V GDP P V WRR  G   +P
Sbjct: 195 VGERDSDPAELVVYERPVLVRRPVNQVVMEEDTVDFQCEVHGDPAPTVRWRREEG--ELP 252

Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
            GR ++ +   LRL +V   DEG Y+C +ENSVG   AS  L V+ PP I   P      
Sbjct: 253 RGRFEIHNGNILRLFHVKEEDEGMYTCTSENSVGKTEASAMLQVHVPPQIATKPRDQIAT 312

Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
            G    F C  TG P P +FW  EG++ ++FPG    +    +V      LTI D    D
Sbjct: 313 QGRSVTFECGTTGNPPPAIFWQKEGSQMLLFPGQPPSQSGRYSVSMSGD-LTITDVHPED 371

Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVT-SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
           S    +C A++ AGS   +  L V     +R PPII  GP+NQT  + +     C  I  
Sbjct: 372 S-GFYICQAISVAGSVMSKVLLDVEGGPSNRIPPIIRQGPANQTATLGATVQLHCRVIGG 430

Query: 425 PEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
           P   I+W   GE L  N  R  +  +GTL + D+ ++DSGTYTC+ASS  G+  WSG L 
Sbjct: 431 PSIHISWEKNGEELHGNEARLTLMENGTLQITDIKETDSGTYTCIASSATGESSWSGTLT 490

Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543
           V           R ++   LPGPP KP+   VT  +VTL+W  N   G +++  Y +E F
Sbjct: 491 VRE--YGVYSTSRISEFIQLPGPPQKPVMTEVTKNTVTLTWQSNPHEGGAAVTSYIIEAF 548

Query: 544 SRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
           S+   S          W  +A  V Q  + V  L P   Y+FIVR  NS+GLS PSP+S+
Sbjct: 549 SQSVGS---------TWQTVADHVKQERHTVVGLFPNTVYLFIVRAVNSYGLSDPSPISE 599

Query: 604 SVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMW 653
            V   D S +   G GV +    R   L D  V L +   +   +  L W
Sbjct: 600 PVRTQDGSPT---GEGVDHRQVQRE--LGDVSVYLQKPVILSPTSASLSW 644



 Score =  118 bits (284), Expect = 1e-24
 Identities = 83/291 (28%), Positives = 133/291 (45%), Gaps = 19/291 (6%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
           E P ++ +P++  V         C   G P+P +RW +       +  R          L
Sbjct: 209 ERPVLVRRPVNQVVMEEDTVDFQCEVHGDPAPTVRWRR----EEGELPRGRFEIHNGNIL 264

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
           R  H +   D G+Y C + NS G   + +A L V V   +   +P  + + QG +V  EC
Sbjct: 265 RLFHVK-EEDEGMYTCTSENSVGKTEA-SAMLQVHV-PPQIATKPRDQIATQGRSVTFEC 321

Query: 130 LPPRGSPEPNVYWKKNG-QTLLFDG-----DSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
               G+P P ++W+K G Q LLF G       R  +   G+L I D    D+G Y C A 
Sbjct: 322 -GTTGNPPPAIFWQKEGSQMLLFPGQPPSQSGRYSVSMSGDLTITDVHPEDSGFYICQAI 380

Query: 184 NAAGTRESAI-----ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238
           + AG+  S +           I P +  GP +  A  G++V   CRV G P   + W ++
Sbjct: 381 SVAGSVMSKVLLDVEGGPSNRIPPIIRQGPANQTATLGATVQLHCRVIGGPSIHISWEKN 440

Query: 239 AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
               +    R+ ++++G+L++ ++   D G Y+C A ++ G  S SG LTV
Sbjct: 441 GEELHGNEARLTLMENGTLQITDIKETDSGTYTCIASSATGESSWSGTLTV 491



 Score = 58.4 bits (135), Expect = 1e-06
 Identities = 51/201 (25%), Positives = 76/201 (37%), Gaps = 16/201 (7%)

Query: 283 ASGYLTVYD--PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340
           +SG  T ++  PP I   P+ + V  G  A   C A GRP P + W  +G R  +     
Sbjct: 5   SSGSRTRFEDSPPRIAEDPSDLIVSKGEPATLNCKAEGRPTPIIEWYKDGER--VETDRD 62

Query: 341 RDKYHATAVFDG--VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG---KLTVTSDDDR 395
             + H   +  G    +  ++            C A NY G +  R     + +  DD R
Sbjct: 63  DPRSHRMLLPSGSLFFLRIVHGRRSKPDEGVYTCVARNYLGEAVSRNASLDVAILRDDFR 122

Query: 396 PPPIITNGPSNQTLPIKSMAVFPCT-AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVL 454
                   PS+  +     AV  C      PEPI+ W      +     R     G L++
Sbjct: 123 ------QAPSDVVVAAGEPAVLECVPPRGHPEPIVFWKRNNVRIGSKDDRIAMRGGKLMI 176

Query: 455 KDLDKSDSGTYTCVASSRHGK 475
               KSD+G Y CV  +  G+
Sbjct: 177 SHARKSDAGMYVCVGKNMVGE 197


>UniRef50_Q96MS0 Cluster: Roundabout homolog 3 precursor; n=23;
           Euteleostomi|Rep: Roundabout homolog 3 precursor - Homo
           sapiens (Human)
          Length = 1386

 Score =  436 bits (1073), Expect = e-120
 Identities = 283/834 (33%), Positives = 414/834 (49%), Gaps = 45/834 (5%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-----DTHRSILPAGGL 66
           P I+EQP D+ V+R +PATL CRA G P P I WYK G  V +       HR +LP+G L
Sbjct: 64  PRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGAL 123

Query: 67  FFLRATHGR-VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
           FF R  HGR    D GVY C A N  G A SRNA+L VAVLR++FR  P +   A G+  
Sbjct: 124 FFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPA 183

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
           VLEC+PPRG PEP+V W+K+G  L  + + R+  + GG L++    ++DAG Y C+A N 
Sbjct: 184 VLECVPPRGHPEPSVSWRKDGARLK-EEEGRI-TIRGGKLMMSHTLKSDAGMYVCVASNM 241

Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
           AG RESA A + +  +P  +  P + V    + VTF C V GDP P + WR+    G +P
Sbjct: 242 AGERESAAAEVMVLERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKE--DGELP 299

Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
            GR ++  D SL + +V   DEG Y+C AENSVG   ASG L+V+ PP +   P      
Sbjct: 300 TGRYEIRSDHSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQDQMAA 359

Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
            G    F C   G P P +FW  EG++ ++FP  S       +V      L I    + D
Sbjct: 360 PGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSV-SPRGQLNITAVQRGD 418

Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDD-DRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
           +    VC AV+ AGS   +  L +     D  PP+I  GP+NQTL + S    PC     
Sbjct: 419 A-GYYVCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGN 477

Query: 425 PEPIIAWYFEGEALIQNHRRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
           P+P + W  +G+ L  +  +  T  +GTL + ++ + D G Y+CVA S  G+  WSG L 
Sbjct: 478 PQPSVRWKKDGQWLQGDDLQFKTMANGTLYIANVQEMDMGFYSCVAKSSTGEATWSGWLK 537

Query: 484 V--DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541
           +  D  ++P+       + SS PG P++P+   +T  S+TL+W  N + G +++  Y +E
Sbjct: 538 MREDWGVSPD----PPTEPSSPPGAPSQPVVTEITKNSITLTWKPNPQTG-AAVTSYVIE 592

Query: 542 VFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPV 601
            FS         P     W  +A  V    + V  L P   Y+F+VR   + GLS PSPV
Sbjct: 593 AFS---------PAAGNTWRTVADGVQLETHTVSGLQPNTIYLFLVRAVGAWGLSEPSPV 643

Query: 602 SDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILN-FYY 660
           S+ V   D S S      V +    +   L +  V L E   +  +T+++ W +      
Sbjct: 644 SEPVRTQDSSPS----RPVEDPWRGQQG-LAEVAVRLQEPIVLGPRTLQVSWTVDGPVQL 698

Query: 661 LEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN 720
           ++G  + +R        + M   L S       +  L   T+ +  +    ++  G  S 
Sbjct: 699 VQGFRVSWRVAGPEGGSWTMLD-LQSPSQQSTVLRGLPPGTQIQIKVQAQGQEGLGAESL 757

Query: 721 SRVAQTLDDVPDGPPINIEMFI--LNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPA 778
           S      ++ P GPP  + + +     +++ + W PP    QNG+IT Y +   W     
Sbjct: 758 SVTRSIPEEAPSGPPQGVAVALGGDGNSSITVSWEPPLPSQQNGVITEYQI---W--CLG 812

Query: 779 NKSMVAIN-TTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDS 831
           N+S   +N +    A S ++  L  G+ Y   +AA T  G+G  S  V   + S
Sbjct: 813 NESRFHLNRSAAGWARSAMLRGLVPGLLYRTLVAAATSAGVGVPSAPVLVQLPS 866



 Score =  126 bits (303), Expect = 5e-27
 Identities = 102/339 (30%), Positives = 157/339 (46%), Gaps = 40/339 (11%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
           E P  + +P++  V    P T  C   G P P +RW K             LP  G + +
Sbjct: 256 ERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRK---------EDGELPT-GRYEI 305

Query: 70  RATH----GRVHS-DAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESKQSAQGD 123
           R+ H    G V + D G Y C A NS G A  S + ++HV     +   +P+ + +A G+
Sbjct: 306 RSDHSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVP---PQLVTQPQDQMAAPGE 362

Query: 124 TVVLECLPPRGSPEPNVYWKKNG-QTLLFDGDS-----RMHLVDGGNLVIQDARQTDAGR 177
           +V  +C   +G+P P ++W+K G Q LLF   S     R  +   G L I   ++ DAG 
Sbjct: 363 SVAFQC-ETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGY 421

Query: 178 YQCIARNAAGT-RESAIATLK----IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
           Y C A + AG+    A+  +K      + P ++ GP +     GSSV   CRV G+P P 
Sbjct: 422 YVCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPS 481

Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-- 290
           V W++          + K + +G+L + NV   D G YSC A++S G  + SG+L +   
Sbjct: 482 VRWKKDGQWLQGDDLQFKTMANGTLYIANVQEMDMGFYSCVAKSSTGEATWSGWLKMRED 541

Query: 291 -----DPPSINLSPNSVNVES--GNVARFTCTATGRPEP 322
                DPP+   SP     +     + + + T T +P P
Sbjct: 542 WGVSPDPPTEPSSPPGAPSQPVVTEITKNSITLTWKPNP 580



 Score = 45.2 bits (102), Expect = 0.011
 Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 3/86 (3%)

Query: 9   GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
           G  P I++ P + T+       L CR  G+P P++RW K G  +  D  +    A G  +
Sbjct: 448 GLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTMANGTLY 507

Query: 69  LRATHGRVHSDAGVYWCEATNSYGTA 94
           +         D G Y C A +S G A
Sbjct: 508 IANVQ---EMDMGFYSCVAKSSTGEA 530


>UniRef50_UPI0000E4900E Cluster: PREDICTED: similar to transmembrane
            receptor Roundabout3; n=2; Strongylocentrotus
            purpuratus|Rep: PREDICTED: similar to transmembrane
            receptor Roundabout3 - Strongylocentrotus purpuratus
          Length = 1613

 Score =  429 bits (1057), Expect = e-118
 Identities = 290/859 (33%), Positives = 426/859 (49%), Gaps = 49/859 (5%)

Query: 38   SPSPAIRWYKGG--VLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTAR 95
            +P   + W K G  + +  D H + L  G LFFLR    RV  D GVY C ATNS G A 
Sbjct: 175  APRFQVNWLKDGQPLEMKGDGHLTALSTGALFFLRVIP-RV--DIGVYQCVATNSLGVAY 231

Query: 96   SRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155
            S+NA+L +A LR +FR EP    +  G+ VVLEC PPRG PEP V W++NGQT++ DG  
Sbjct: 232  SKNASLDIAYLRGDFRQEPSDTMALLGEAVVLECSPPRGHPEPEVSWERNGQTVVEDG-I 290

Query: 156  RMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT 215
            R+ ++  GNLVI   + +D G Y C+A N+ G + SA   L I+ +P     P D +A  
Sbjct: 291  RVRILTDGNLVISQPKSSDIGNYVCVATNSEGAKRSAAGRLIINSRPAFTEVPFDTLAIP 350

Query: 216  GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAE 275
            G ++T  C   G+P P + W +    G +PL R  +L D SLR+ N   +D G Y C A+
Sbjct: 351  GETITLPCVAEGEPAPTIRWVKQ--DGTLPLNRNTMLQDSSLRISNAESSDSGTYICTAQ 408

Query: 276  NSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII 335
            N+ G  S    +TV   P     P    V  G  A F C ATG P P+++W   G + ++
Sbjct: 409  NTWGDKSVEAIVTVSSAPMFTRVPVDRTVVVGQDAFFLCQATGLPTPSIYWKERGAKPLM 468

Query: 336  FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395
            FPG    ++  T   DG   L  + T +N+     VCSA++  GS      L V  D+  
Sbjct: 469  FPGDRNAQFEVTN--DGRLHL-FSVTRENE--GYYVCSAMSGRGSVEDSAYLRVLDDNLP 523

Query: 396  PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVL 454
             PPII  GPSNQTL   S A   C A    +P I W  +G  L +   R  +   GTL  
Sbjct: 524  LPPIIHIGPSNQTLVEGSPAQLICQAEGRSQPSIDWLKDGAPLQLVGTRITLDGSGTLKF 583

Query: 455  KDLDKSDSGTYTCVASSRHGKYVWSGAL-LVDSPINPNIHFFRAADVSSLPGPPTKPITH 513
              L   D+G+YTC A++  G   WS +L ++            A  V+ LP  P  PI  
Sbjct: 584  SSLTPDDAGSYTCSAANSVGATKWSSSLQVIRRAFAGTEQVHEAPSVTQLPQAPGFPIVD 643

Query: 514  NVTDTSVTLSWSQNNKI--GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTH 571
            N+T T++ L+W     +   + S+ GY+VE F         TP    GW V A R+    
Sbjct: 644  NITRTTMRLTWPSARPLPDRTVSLTGYRVEYF---------TPDRITGWTVAAVRIQGNS 694

Query: 572  YVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEG----TGVSN-STE- 625
            + V++L PG TY+F+VR  N+HG   PSPVS +      ++    G     GV+  +TE 
Sbjct: 695  FEVRNLEPGFTYVFMVRGINAHGYGPPSPVSIAANTPTGTHREVPGPNAEPGVTTPATEG 754

Query: 626  -YRNNILTDHI----VELIEATPIDSKTIKLMWEIL-NFYYLEGLFIYFRPLDNITIEYE 679
                +IL D +    V +     + ++ I + W+I+ N  Y++G ++   P       +E
Sbjct: 755  AESRDILQDKLDNCGVYIKRVQVLGTQAINVTWQIIRNGDYIDGYYLKVTPQVKAPGIFE 814

Query: 680  MKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKF-EGKPSNSRVAQTLDDVPDGPPINI 738
            M  ++  ND +  +   L+ +T+Y   + P++  +  G+ S   V +T  DVP  PP +I
Sbjct: 815  MNRVV--NDKTAVQ-GGLQPWTEYAITIQPYHGAWHRGRESRKVVIKTAQDVPRAPPNSI 871

Query: 739  EMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMT 798
            +     +T++ + W PP +    GII GY++     + P + +   I T  ++   + + 
Sbjct: 872  KARQNGSTSIKVSWRPPAVNQVPGIIAGYHIFCLSENPPHHPN---ITTRNNRTLEVAVP 928

Query: 799  NLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAG-DFVM 857
            NL  G  Y V++AA TI G+GPFS  VY  +     G D   +   N  +    G D + 
Sbjct: 929  NLRPGAQYGVKVAAYTIAGMGPFSDIVYVTLPP---GPDDPEKRGSNDGLDSGGGMDILS 985

Query: 858  ETWFYFLIGAIVLFKIIVI 876
            E WFY  +   +LF I  I
Sbjct: 986  EPWFYAAVALALLFVITSI 1004



 Score =  203 bits (495), Expect = 3e-50
 Identities = 167/527 (31%), Positives = 249/527 (47%), Gaps = 46/527 (8%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG--VLVVSDTHRSILPAGGLFFL 69
           P I E P   ++ ++ PATLNCRA G P+P + W K G  + +  D H + L  G LFFL
Sbjct: 65  PRITEHPSGQSIRKNSPATLNCRAEGFPAPDLHWLKDGQPLEMKGDGHLTALSTGALFFL 124

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
           R    RV  D GVY C ATNS G A S+NA+L +A    ++ +          ++ V+ C
Sbjct: 125 RVI-PRV--DIGVYQCVATNSLGVAYSKNASLDIASFVMDWGI-------TSFESGVMAC 174

Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNL-VIQDARQTDAGRYQCIARNAAGT 188
                +P   V W K+GQ L   GD  +  +  G L  ++   + D G YQC+A N+ G 
Sbjct: 175 -----APRFQVNWLKDGQPLEMKGDGHLTALSTGALFFLRVIPRVDIGVYQCVATNSLGV 229

Query: 189 RESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVLWRRSAGGGNMPL 246
             S  A+L I +++      P D +A  G +V  +C    G P P+V W R+        
Sbjct: 230 AYSKNASLDIAYLRGDFRQEPSDTMALLGEAVVLECSPPRGHPEPEVSWERNGQTVVEDG 289

Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV-SASGYLTVYDPPSINLSPNSVNVE 305
            RV++L DG+L +     +D G Y C A NS GA  SA+G L +   P+    P      
Sbjct: 290 IRVRILTDGNLVISQPKSSDIGNYVCVATNSEGAKRSAAGRLIINSRPAFTEVPFDTLAI 349

Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
            G      C A G P PT+ W V+ + T+    ++R+    T + D  + L I++ + +D
Sbjct: 350 PGETITLPCVAEGEPAPTIRW-VKQDGTL---PLNRN----TMLQD--SSLRISNAESSD 399

Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
           S  T +C+A N  G   V   +TV+S      P+ T  P ++T+ +   A F C A   P
Sbjct: 400 S-GTYICTAQNTWGDKSVEAIVTVSS-----APMFTRVPVDRTVVVGQDAFFLCQATGLP 453

Query: 426 EPIIAWYFEGEALI-----QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
            P I W   G   +     +N +  VTNDG L L  + + + G Y C A S  G    S 
Sbjct: 454 TPSIYWKERGAKPLMFPGDRNAQFEVTNDGRLHLFSVTRENEGYYVCSAMSGRGSVEDSA 513

Query: 481 ALLV---DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSW 524
            L V   + P+ P IH    ++ + + G P + I      +  ++ W
Sbjct: 514 YLRVLDDNLPLPPIIH-IGPSNQTLVEGSPAQLICQAEGRSQPSIDW 559



 Score = 62.5 bits (145), Expect = 7e-08
 Identities = 65/240 (27%), Positives = 100/240 (41%), Gaps = 21/240 (8%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG---VLVVSDTHR--SI 60
           VT   AP     P+D TV   Q A   C+A G P+P+I W + G   ++   D +    +
Sbjct: 420 VTVSSAPMFTRVPVDRTVVVGQDAFFLCQATGLPTPSIYWKERGAKPLMFPGDRNAQFEV 479

Query: 61  LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV----AVLREEFRLEPES 116
              G L     T      + G Y C A +  G+    +A L V      L     + P +
Sbjct: 480 TNDGRLHLFSVT----RENEGYYVCSAMSGRGSVED-SAYLRVLDDNLPLPPIIHIGPSN 534

Query: 117 KQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAG 176
           +   +G    L C    G  +P++ W K+G  L   G +R+ L   G L        DAG
Sbjct: 535 QTLVEGSPAQLIC-QAEGRSQPSIDWLKDGAPLQLVG-TRITLDGSGTLKFSSLTPDDAG 592

Query: 177 RYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
            Y C A N+ G  + + ++L++  + +   G E V      SVT   +  G P+ D + R
Sbjct: 593 SYTCSAANSVGATKWS-SSLQVIRRAF--AGTEQV--HEAPSVTQLPQAPGFPIVDNITR 647



 Score = 43.2 bits (97), Expect = 0.044
 Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 3/85 (3%)

Query: 393 DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI---QNHRRNVTND 449
           ++  PP IT  PS Q++   S A   C A   P P + W  +G+ L      H   ++  
Sbjct: 60  NEESPPRITEHPSGQSIRKNSPATLNCRAEGFPAPDLHWLKDGQPLEMKGDGHLTALSTG 119

Query: 450 GTLVLKDLDKSDSGTYTCVASSRHG 474
               L+ + + D G Y CVA++  G
Sbjct: 120 ALFFLRVIPRVDIGVYQCVATNSLG 144


>UniRef50_UPI0000E46659 Cluster: PREDICTED: similar to roundabout
           homolog 2; n=2; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to roundabout homolog 2 -
           Strongylocentrotus purpuratus
          Length = 1809

 Score =  412 bits (1014), Expect = e-113
 Identities = 239/655 (36%), Positives = 338/655 (51%), Gaps = 30/655 (4%)

Query: 7   TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGG 65
           T   AP I EQP  + V R  PA+ NC+A G P P I W K G  LV+ DT  ++L +G 
Sbjct: 17  TEESAPTITEQPKSLIVTRGDPASFNCKAEGRPEPTISWLKNGQPLVIRDTRHTVLDSGS 76

Query: 66  LFFLRATHGRVHS-DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
           LFFL+    R    D GVY C A NS GTA S NATL +A LRE+FR EP S Q   GD+
Sbjct: 77  LFFLQVVGNRQGGQDGGVYQCMAHNSLGTAYSANATLEIAYLREDFREEPVSDQLISGDS 136

Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
            VLEC PPRG P P V W K+ Q ++ D ++R+ +V+ GNL++++ R+ D G Y+C A+N
Sbjct: 137 AVLECTPPRGYPTPEVTWLKDDQPIILD-NNRVKIVEDGNLLLKELRKDDEGTYKCKAQN 195

Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
            AG R S  A L + +KP  I  P+D +   G +   +C V GDP P V W R    G +
Sbjct: 196 VAGERISKDAYLTVQVKPAFINPPQDTITAPGEAAVLRCEVEGDPPPTVSWSREI--GEL 253

Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
           P GR + L D SLR+ +    D+G Y C AEN  G   A   L V   P    +P    V
Sbjct: 254 PDGRTQQLPDNSLRIRHTDELDDGVYICTAENIWGTSDAKARLRVSAVPDFIRAPRDKTV 313

Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNR-TIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
               + RF C A G P P++ W   G    ++F    R ++  +A  +    L IN    
Sbjct: 314 HVNEMVRFQCEAVGSPPPSIHWQKAGTEDNLLFINQQRGRFEVSASGE----LQINPVQM 369

Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
           +D+  T +C A    G +  +  L V  +   PPP+I  GP+NQTL + S A F C +  
Sbjct: 370 DDA-GTYICYATGGTGVAEAKAVLRVLDESLAPPPLIQYGPANQTLVVGSTATFMCRSAG 428

Query: 424 TPEPIIAWYFEGEALIQNHRR--NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
            P P I W  +G AL  ++ R   +  D TL +  +   DSG Y+C+ASS  G+   S  
Sbjct: 429 NPSPQIEWTKDGIALTTSNPRFSLMYPDNTLEITGVQVDDSGLYSCLASSNSGETSQSAT 488

Query: 482 LLV-DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQV 540
           LLV +S     I    A  ++ LPG P++P+  NVT +S+ + W+      + S+ GYQV
Sbjct: 489 LLVIESTETSGIPVKTAPSINELPGSPSQPLRVNVTRSSIQVRWTAPAANRAPSVTGYQV 548

Query: 541 EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600
           E FS         P    GWVV    +    Y +  L+P  +++ +VR  NS+G+  P P
Sbjct: 549 EYFS---------PERVTGWVVAGNGIQGETYNINHLVPSSSHLVVVRAINSNGIGPPGP 599

Query: 601 VSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEI 655
           +S+S++  +      E      S E  ++  +   VE+     + S  IK+ WE+
Sbjct: 600 MSESISTSE------ETANPPPSRECLSD-QSSITVEITTIIALSSTAIKVSWEV 647



 Score =  116 bits (279), Expect = 4e-24
 Identities = 106/355 (29%), Positives = 148/355 (41%), Gaps = 37/355 (10%)

Query: 3   DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
           D Y+T    P  I  P D   A  + A L C   G P P + W +  +  + D     LP
Sbjct: 204 DAYLTVQVKPAFINPPQDTITAPGEAAVLRCEVEGDPPPTVSWSR-EIGELPDGRTQQLP 262

Query: 63  AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122
                 LR  H     D GVY C A N +GT+ ++ A L V+ +  +F   P  K     
Sbjct: 263 DNS---LRIRH-TDELDDGVYICTAENIWGTSDAK-ARLRVSAV-PDFIRAPRDKTVHVN 316

Query: 123 DTVVLECLPPRGSPEPNVYWKKNG--QTLLFDGD--SRMHLVDGGNLVIQDARQTDAGRY 178
           + V  +C    GSP P+++W+K G    LLF      R  +   G L I   +  DAG Y
Sbjct: 317 EMVRFQC-EAVGSPPPSIHWQKAGTEDNLLFINQQRGRFEVSASGELQINPVQMDDAGTY 375

Query: 179 QCIARNAAGTRESAIATLKIHIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233
            C A    G  E A A L++  +     P +  GP +     GS+ TF CR  G+P P +
Sbjct: 376 ICYATGGTGVAE-AKAVLRVLDESLAPPPLIQYGPANQTLVVGSTATFMCRSAGNPSPQI 434

Query: 234 LWRRSAGGGNMPLGRVKVL-DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD- 291
            W +          R  ++  D +L +  V + D G YSC A ++ G  S S  L V + 
Sbjct: 435 EWTKDGIALTTSNPRFSLMYPDNTLEITGVQVDDSGLYSCLASSNSGETSQSATLLVIES 494

Query: 292 ----------PPSINLSPNS------VNVESGNV-ARFTCTATGRPEPTMFWSVE 329
                      PSIN  P S      VNV   ++  R+T  A  R      + VE
Sbjct: 495 TETSGIPVKTAPSINELPGSPSQPLRVNVTRSSIQVRWTAPAANRAPSVTGYQVE 549



 Score = 87.8 bits (208), Expect = 2e-15
 Identities = 90/375 (24%), Positives = 146/375 (38%), Gaps = 32/375 (8%)

Query: 515 VTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVV 574
           ++ T++ +SW  +       I GYQV     +  S  +              V     ++
Sbjct: 636 LSSTAIKVSWEVHTPANEDQIDGYQVRYLLSDGASRTH----------FQTVVGMLSTIL 685

Query: 575 KSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDH 634
             L P + Y   VR +  +     SP   + T+ + S  L     V        N L   
Sbjct: 686 TGLDPSMDYTVSVRPQICNSKGQESPSVAARTMSEGSGPLC----VHGDNRILQNKLDGS 741

Query: 635 IVELIEATPIDSKTIKLMWEILNF--YYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGF 692
            V ++    + S  +++ WEI      Y+EG  I +R   + +  Y ++TI  +     F
Sbjct: 742 DVHIVGTETVGSNALQVKWEIARHAAAYVEGFHIKYRTSSSSSSNYSVETI--TGPARTF 799

Query: 693 EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKW 752
            +  L  + +Y   + PF   + G+        T  D P GPP N+      T+ V ++W
Sbjct: 800 VLNGLTSWQEYSISVQPFSGLYCGQEGEQIKTWTAADRPRGPPRNVIARSNGTSAVLVQW 859

Query: 753 SPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLI--MTNLTSGVSYSVQI 810
             P   L  G I GY     ++    N S  A N T+   T+ I  +  L +G  Y VQ+
Sbjct: 860 HAPGRDLVQGYIEGY-----YISCRGNISSHARNRTIQGNTTFIGRVGGLQAGKVYWVQV 914

Query: 811 AAETIIGLGPFSQKVYFNIDSR-SVGLDLLSRYPMNGEVSIVAGDFVMETWFYFLIGAIV 869
           AA T  G GP S  V   + S   +   L    P N     + G+   + W Y +I  IV
Sbjct: 915 AAFTAAGAGPSSPVVLVTVASPIPIDAGLADSDPEN-----IDGE-ATKPWVYAIIATIV 968

Query: 870 LFKIIVIAGIIYVRK 884
               +V+   +  R+
Sbjct: 969 FIIALVLIAFVLRRR 983



 Score = 79.0 bits (186), Expect = 7e-13
 Identities = 70/248 (28%), Positives = 102/248 (41%), Gaps = 19/248 (7%)

Query: 285 GYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
           G  T    P+I   P S+ V  G+ A F C A GRPEPT+ W   G   +I     RD  
Sbjct: 14  GRRTEESAPTITEQPKSLIVTRGDPASFNCKAEGRPEPTISWLKNGQPLVI-----RDTR 68

Query: 345 HATAVFDGVTVL-TINDTDKNDSRNTIVCSAVNYAGSSFVRG---KLTVTSDDDRPPPII 400
           H       +  L  + +           C A N  G+++      ++    +D R  P+ 
Sbjct: 69  HTVLDSGSLFFLQVVGNRQGGQDGGVYQCMAHNSLGTAYSANATLEIAYLREDFREEPV- 127

Query: 401 TNGPSNQTLPIKSMAVFPCT-AICTPEPIIAWYFEGEALI-QNHRRNVTNDGTLVLKDLD 458
               S+Q +   S AV  CT     P P + W  + + +I  N+R  +  DG L+LK+L 
Sbjct: 128 ----SDQLISGDS-AVLECTPPRGYPTPEVTWLKDDQPIILDNNRVKIVEDGNLLLKELR 182

Query: 459 KSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDT 518
           K D GTY C A +  G+ +   A L    + P        D  + PG           D 
Sbjct: 183 KDDEGTYKCKAQNVAGERISKDAYLT-VQVKP-AFINPPQDTITAPGEAAVLRCEVEGDP 240

Query: 519 SVTLSWSQ 526
             T+SWS+
Sbjct: 241 PPTVSWSR 248


>UniRef50_UPI0000ECA411 Cluster: UPI0000ECA411 related cluster; n=1;
           Gallus gallus|Rep: UPI0000ECA411 UniRef100 entry -
           Gallus gallus
          Length = 1213

 Score =  341 bits (838), Expect = 7e-92
 Identities = 192/464 (41%), Positives = 257/464 (55%), Gaps = 20/464 (4%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD----THRSILPAGGL 66
           AP I+E P D+ V+R +PATL+CRA G PSP + WYK G  V +D    +HR +LP+G L
Sbjct: 10  APRIVEHPSDLLVSRGEPATLSCRAEGRPSPTVEWYKDGERVETDKDPRSHRMLLPSGSL 69

Query: 67  FFLRATHGRVHS-DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
           FF R  HGR    D G+Y C A N YG A SRNA+L VAVLR++FR  P     A G+  
Sbjct: 70  FF-RIVHGRRSKPDEGIYVCVARN-YGEATSRNASLEVAVLRDDFRQSPGDVVVAAGEPA 127

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
           VLEC+PPRG PEP V WKK+G T L D D R+  + GG L++   R++DAG Y C+A N 
Sbjct: 128 VLECVPPRGHPEPTVTWKKDG-TRLSDKDERI-TIRGGKLMMATTRKSDAGIYVCVATNM 185

Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
            G R+S  A L +  +P     P++       +  F C   GDPLP   WRR    G +P
Sbjct: 186 VGERDSEPAELVVFERPAFGRRPQNQAVLEDQAAEFPCEALGDPLPTARWRRE--DGELP 243

Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
            GR ++L D +LR+  V   DEG Y+C AENSVG   ASG L V  PP +   P +  V 
Sbjct: 244 AGRWELLADNTLRISRVRAEDEGTYTCMAENSVGRSEASGTLIVRVPPQLITRPRNQTVS 303

Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD--GVTVLTINDTDK 363
            G    F C  TG P P +FW  EG++T++FPG S       +V     +T+ T+  TD 
Sbjct: 304 PGQTVTFQCETTGNPPPAVFWQKEGSQTLLFPGQSPPPASRISVASSGAMTIATVQPTD- 362

Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP-PPIITNGPSNQT-LPIKSMAVFPCTA 421
                  +C A++ AGS   +  L V +    P PP+I  GP+N T LP+ +    PC A
Sbjct: 363 ---AGYYLCQAISVAGSILAKALLEVEAAPAEPRPPLIRWGPANLTVLPVGATVQLPCWA 419

Query: 422 ICTPEPIIAWYFEGEALIQNH-RRNVTNDGTLVLKDLDKSDSGT 464
              P P + W  +G  +  +  R ++  +GTL +  L  S +GT
Sbjct: 420 EGEPPPRVGWLKDGRTVPGSEGRASLLENGTLQISSLRVSCTGT 463



 Score =  116 bits (279), Expect = 4e-24
 Identities = 113/411 (27%), Positives = 163/411 (39%), Gaps = 39/411 (9%)

Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH--LVDGGNL---VIQ 168
           P     ++G+   L C    G P P V W K+G+ +  D D R H  L+  G+L   ++ 
Sbjct: 17  PSDLLVSRGEPATLSCRA-EGRPSPTVEWYKDGERVETDKDPRSHRMLLPSGSLFFRIVH 75

Query: 169 DAR-QTDAGRYQCIARNAAGTRESAIATLKIHI-KPYLITGPEDVVAQTGSSVTFQC-RV 225
             R + D G Y C+ARN  G   S  A+L++ + +      P DVV   G     +C   
Sbjct: 76  GRRSKPDEGIYVCVARNY-GEATSRNASLEVAVLRDDFRQSPGDVVVAAGEPAVLECVPP 134

Query: 226 GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV-SAS 284
            G P P V W++     +    R+ +   G L +     +D G Y C A N VG   S  
Sbjct: 135 RGHPEPTVTWKKDGTRLSDKDERITIRG-GKLMMATTRKSDAGIYVCVATNMVGERDSEP 193

Query: 285 GYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
             L V++ P+    P +  V     A F C A G P PT  W  E         +   ++
Sbjct: 194 AELVVFERPAFGRRPQNQAVLEDQAAEFPCEALGDPLPTARWRREDGE------LPAGRW 247

Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404
              A       L I+     D   T  C A N  G S   G L V     R PP +   P
Sbjct: 248 ELLAD----NTLRISRVRAEDE-GTYTCMAENSVGRSEASGTLIV-----RVPPQLITRP 297

Query: 405 SNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI--------QNHRRNVTNDGTLVLKD 456
            NQT+       F C     P P + W  EG   +           R +V + G + +  
Sbjct: 298 RNQTVSPGQTVTFQCETTGNPPPAVFWQKEGSQTLLFPGQSPPPASRISVASSGAMTIAT 357

Query: 457 LDKSDSGTYTCVASSRHGKYVWSGALLVD-SPINPNIHFFR--AADVSSLP 504
           +  +D+G Y C A S  G  +    L V+ +P  P     R   A+++ LP
Sbjct: 358 VQPTDAGYYLCQAISVAGSILAKALLEVEAAPAEPRPPLIRWGPANLTVLP 408



 Score = 95.5 bits (227), Expect = 8e-18
 Identities = 87/273 (31%), Positives = 127/273 (46%), Gaps = 24/273 (8%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFF 68
           E P    +P +  V   Q A   C A G P P  RW +  G L      R  L A     
Sbjct: 200 ERPAFGRRPQNQAVLEDQAAEFPCEALGDPLPTARWRREDGELPAG---RWELLADNT-- 254

Query: 69  LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
           LR +  R   D G Y C A NS G + + + TL V V   +    P ++  + G TV  +
Sbjct: 255 LRISRVRA-EDEGTYTCMAENSVGRSEA-SGTLIVRV-PPQLITRPRNQTVSPGQTVTFQ 311

Query: 129 CLPPRGSPEPNVYWKKNG-QTLLFDGD-----SRMHLVDGGNLVIQDARQTDAGRYQCIA 182
           C    G+P P V+W+K G QTLLF G      SR+ +   G + I   + TDAG Y C A
Sbjct: 312 C-ETTGNPPPAVFWQKEGSQTLLFPGQSPPPASRISVASSGAMTIATVQPTDAGYYLCQA 370

Query: 183 RNAAGTRESAIATLKIHI-----KPYLIT-GPEDV-VAQTGSSVTFQCRVGGDPLPDVLW 235
            + AG+   A A L++       +P LI  GP ++ V   G++V   C   G+P P V W
Sbjct: 371 ISVAGS-ILAKALLEVEAAPAEPRPPLIRWGPANLTVLPVGATVQLPCWAEGEPPPRVGW 429

Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268
            +         GR  +L++G+L++ ++ ++  G
Sbjct: 430 LKDGRTVPGSEGRASLLENGTLQISSLRVSCTG 462



 Score = 91.5 bits (217), Expect = 1e-16
 Identities = 87/295 (29%), Positives = 112/295 (37%), Gaps = 24/295 (8%)

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM---PLGRVKVLDDGSLR 258
           P ++  P D++   G   T  CR  G P P V W +          P     +L  GSL 
Sbjct: 11  PRIVEHPSDLLVSRGEPATLSCRAEGRPSPTVEWYKDGERVETDKDPRSHRMLLPSGSLF 70

Query: 259 LDNV----ILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLSPNSVNVESGNVARFT 313
              V       DEG Y C A N   A S +  L V         SP  V V +G  A   
Sbjct: 71  FRIVHGRRSKPDEGIYVCVARNYGEATSRNASLEVAVLRDDFRQSPGDVVVAAGEPAVLE 130

Query: 314 CTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
           C    G PEPT+ W  +G R         DK     +  G  ++    T K+D+    VC
Sbjct: 131 CVPPRGHPEPTVTWKKDGTRL-------SDKDERITIRGGKLMMAT--TRKSDA-GIYVC 180

Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
            A N  G         V  +     P     P NQ +     A FPC A+  P P   W 
Sbjct: 181 VATNMVGERDSEPAELVVFER----PAFGRRPQNQAVLEDQAAEFPCEALGDPLPTARWR 236

Query: 433 FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
            E   L    R  +  D TL +  +   D GTYTC+A +  G+   SG L+V  P
Sbjct: 237 REDGELPAG-RWELLADNTLRISRVRAEDEGTYTCMAENSVGRSEASGTLIVRVP 290



 Score = 63.7 bits (148), Expect = 3e-08
 Identities = 43/140 (30%), Positives = 63/140 (45%), Gaps = 7/140 (5%)

Query: 691 GFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHL 750
           G  +T LR+   YE  + PFY    G  S  R  +  +  P  PP  + +   N T+V +
Sbjct: 599 GALLTGLRRGQDYEVKVRPFYLHLHGPDSAVRALRMPEAAPSAPPRAVSV-AGNGTSVRI 657

Query: 751 KWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH-QATSLIMTNLTSGVSYSVQ 809
            W PP    QNG+I  Y +   W     N+S   IN +V     + ++  L  GV Y  +
Sbjct: 658 SWQPPPPAEQNGVILDYRI---W--CLGNESRFHINQSVEGTVLATVLRGLVPGVPYRAE 712

Query: 810 IAAETIIGLGPFSQKVYFNI 829
           +AA T  G+G  S  +   I
Sbjct: 713 VAAATGAGVGARSAPISIRI 732


>UniRef50_A1XCJ3 Cluster: RoboA; n=1; Schmidtea mediterranea|Rep:
           RoboA - Schmidtea mediterranea (Freshwater planarian
           flatworm)
          Length = 1402

 Score =  281 bits (689), Expect = 8e-74
 Identities = 189/608 (31%), Positives = 276/608 (45%), Gaps = 32/608 (5%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-----DTHRSILPAG 64
           + P I E P        Q  +L C A G P P I WYK G +V S      T   ++   
Sbjct: 24  QKPIISEHPASTHGLSLQRVSLRCSAKGDPMPNIIWYKDGQVVESYRDKPATSNRLVKDN 83

Query: 65  GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
            L F+         D GVY+C A+N +G   S NA++ +A L ++  + PESK ++ G+T
Sbjct: 84  ELLFMHLDT----QDEGVYYCNASNIHGWTISNNASVLIAFLNKDI-IGPESKTASVGET 138

Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
           V++EC PP+G P+P V WK NG  +  + + R+ ++D GNL I  A + D+GRY C+A+N
Sbjct: 139 VLMECKPPKGVPKPTVIWKFNGNAI--EVNKRIKILDNGNLRIDKATRKDSGRYNCLAKN 196

Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
            A  R+S  A L +  KP     P ++  +   +  F C   GDP P ++WRR      +
Sbjct: 197 FADERDSTSALLTVRQKPQFKIAPSNIEVKVNEAAVFPCVADGDPKPTIVWRRD-NQKKI 255

Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
           P  R  ++D+  +++  V L D G Y C A NS G + A   L+V   P    +P++  V
Sbjct: 256 PSSRATLIDNKGMQISKVQLTDMGNYICHASNSAGHLEAYAKLSVVSTPGFIETPDNQKV 315

Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
             G+ A F C  TG P+PT+ WS  G+  I     SR         D +  LTIN    +
Sbjct: 316 RVGDTAIFNCRVTGSPQPTIIWSHNGDHFIADEENSRRSERIQV--DKLGSLTINPVKIS 373

Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
           DS     C A +Y G       L V       PP+I  GP NQTL I   A F C     
Sbjct: 374 DS-GKYECKASSYIGKIQSSASLHVIDAQKYVPPVIEVGPQNQTLRIGLTATFNCQPKQQ 432

Query: 425 PEPIIAWYFEGEA--LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482
            +  + W   G    L+ + R      G L +  L  SD+G YTC         +WS  L
Sbjct: 433 DDVTVHWLKNGHQLNLVSDPRIITLTTGKLKINLLRMSDAGNYTCKIVQNEAFTLWSVTL 492

Query: 483 -LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541
            ++D             D   LP  PT        D+ +T  W +N     ++I  Y +E
Sbjct: 493 KILDKNDYETAIMQTIDDARMLPSAPTNFEVIERGDSWITFKW-ENPPQEETNINHYLIE 551

Query: 542 VFSRETLSGNNTPRNSR-GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600
                      +P  SR GW  +   +  +   + +L P   Y F++R+ N  G+  P+ 
Sbjct: 552 Y----------SPYESRQGW-YMQSIILSSPGKITNLHPNTGYRFLIRSVNDIGIGNPNV 600

Query: 601 VSDSVTVG 608
           +S  V  G
Sbjct: 601 ISFVVFTG 608



 Score = 95.1 bits (226), Expect = 1e-17
 Identities = 68/278 (24%), Positives = 128/278 (46%), Gaps = 17/278 (6%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
           +T  + P     P ++ V  ++ A   C A G P P I W +     +  +  +++   G
Sbjct: 208 LTVRQKPQFKIAPSNIEVKVNEAAVFPCVADGDPKPTIVWRRDNQKKIPSSRATLIDNKG 267

Query: 66  LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
           +   +       +D G Y C A+NS G   +  A L V V    F   P++++   GDT 
Sbjct: 268 MQISKVQ----LTDMGNYICHASNSAGHLEA-YAKLSV-VSTPGFIETPDNQKVRVGDTA 321

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDS-----RMHLVDGGNLVIQDARQTDAGRYQC 180
           +  C    GSP+P + W  NG   + D ++     R+ +   G+L I   + +D+G+Y+C
Sbjct: 322 IFNC-RVTGSPQPTIIWSHNGDHFIADEENSRRSERIQVDKLGSLTINPVKISDSGKYEC 380

Query: 181 IARNAAGTRESA----IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
            A +  G  +S+    +   + ++ P +  GP++   + G + TF C+        V W 
Sbjct: 381 KASSYIGKIQSSASLHVIDAQKYVPPVIEVGPQNQTLRIGLTATFNCQPKQQDDVTVHWL 440

Query: 237 RSAGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCE 273
           ++    N+    R+  L  G L+++ + ++D G Y+C+
Sbjct: 441 KNGHQLNLVSDPRIITLTTGKLKINLLRMSDAGNYTCK 478



 Score = 60.5 bits (140), Expect = 3e-07
 Identities = 64/253 (25%), Positives = 110/253 (43%), Gaps = 27/253 (10%)

Query: 694 ITSLRKYTKYEFFLIPF-----YKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTV 748
           I+ L  +  Y+ ++ P+     + K  G  S +    T D VP   P ++    L+ T+V
Sbjct: 733 ISKLEPFVCYDVYVQPYLDNNKFGKLTGTVSKAITILTYDSVPTKSPTDLTARWLSNTSV 792

Query: 749 HLKWSPPELQLQNGIITGYNVVVNWLDVPANKSM-VAINTTVHQATSLIMTNLTSGVSYS 807
            + W P  ++  NGI+ GY++ +   D  + +S+ V+  +TV +   L++      + Y 
Sbjct: 793 EISWKPAPMRHINGILKGYSLHIIGNDTNSTRSIEVSPKSTVVRVQDLLI-----NMPYI 847

Query: 808 VQIAAETIIGLGPFSQKVYFNIDSRSVGLD---LLSRYPMNGEVSIVAGDFVMETWF--Y 862
           V IAA T  G G  S  +     S  + +    L  R   N    I+A     + WF   
Sbjct: 848 VHIAASTCQGEGICSAGLMLTASSSLITMSPNYLERRLGQNFAKPIIA-SVTKQPWFISI 906

Query: 863 FLIGAIVLFKIIVIAGIIYVRKYNIFAKKSALPNIYDSNGTSLVTQMNIKAAVS------ 916
            ++G  + F   +I   I V   +++ +     + Y SNGT L++  N +  V       
Sbjct: 907 MVVGGCLWF---MICAFILVVCRSMYLRGLIYKSGY-SNGTKLISNSNSQLPVGSSNGRL 962

Query: 917 LSHPLTSCYNKNT 929
            SH + S  N NT
Sbjct: 963 TSHQIVSHMNTNT 975


>UniRef50_UPI0000EBE6C5 Cluster: PREDICTED: hypothetical protein;
           n=3; Bos taurus|Rep: PREDICTED: hypothetical protein -
           Bos taurus
          Length = 349

 Score =  280 bits (687), Expect = 1e-73
 Identities = 145/327 (44%), Positives = 189/327 (57%), Gaps = 10/327 (3%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-----THRSILPAGGL 66
           P I+EQP D+ V+R +PATL CRA G P P I WYK G  V +       HR +LP+G L
Sbjct: 20  PRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATAREDPRAHRLLLPSGAL 79

Query: 67  FFLRATHGR-VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
           FF R  HGR    D GVY C A N  G A SRNA+L VAVLR++FR  P +   A G+  
Sbjct: 80  FFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPA 139

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
           V+EC+PPRG PEP+V WKK+G   L + + R+  + GG L++    ++DAG Y C+A N 
Sbjct: 140 VMECMPPRGHPEPSVSWKKDG-VRLKEEEGRI-TIRGGKLMMSHTFKSDAGMYVCVASNM 197

Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
           AG RES  A L +  +P  +  P + V   G+ V F C V GDP P + WR+    G +P
Sbjct: 198 AGERESGAAKLVVLERPSFLRRPVNQVVLAGAPVDFPCEVQGDPPPRLRWRKE--DGELP 255

Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
            GR ++  D SL++  V   DEG Y+C AENSVG   ASG L V+ PP +   P      
Sbjct: 256 TGRYEIQSDHSLQIGRVSAEDEGTYTCVAENSVGRAEASGSLIVHVPPQLVTQPQDQMAA 315

Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNR 332
            G+   F C   G P P +FW  EG++
Sbjct: 316 PGDSVAFQCETKGNPPPAIFWQKEGSQ 342



 Score =  116 bits (278), Expect = 5e-24
 Identities = 74/230 (32%), Positives = 107/230 (46%), Gaps = 11/230 (4%)

Query: 16  EQPLDVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74
           + P +V VA  +PA + C    G P P++ W K GV +  +  R  +  G L     +H 
Sbjct: 126 QSPGNVVVAVGEPAVMECMPPRGHPEPSVSWKKDGVRLKEEEGRITIRGGKLMM---SH- 181

Query: 75  RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRG 134
              SDAG+Y C A+N  G   S  A L V + R  F   P ++    G  V   C   +G
Sbjct: 182 TFKSDAGMYVCVASNMAGERESGAAKL-VVLERPSFLRRPVNQVVLAGAPVDFPC-EVQG 239

Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194
            P P + W+K    L      R  +    +L I      D G Y C+A N+ G R  A  
Sbjct: 240 DPPPRLRWRKEDGEL---PTGRYEIQSDHSLQIGRVSAEDEGTYTCVAENSVG-RAEASG 295

Query: 195 TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
           +L +H+ P L+T P+D +A  G SV FQC   G+P P + W++     N+
Sbjct: 296 SLIVHVPPQLVTQPQDQMAAPGDSVAFQCETKGNPPPAIFWQKEGSQANL 345



 Score = 90.6 bits (215), Expect = 2e-16
 Identities = 86/299 (28%), Positives = 126/299 (42%), Gaps = 29/299 (9%)

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGGGNMPLGRVKVLDDGSL 257
           P ++  P D++   G   T  CR  G P P++ W     R A     P     +L  G+L
Sbjct: 20  PRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATAREDPRAHRLLLPSGAL 79

Query: 258 RLDNVILA-----DEGEYSCEAENSVGAV-SASGYLTVYD-PPSINLSPNSVNVESGNVA 310
               ++       DEG Y+C A N +GA  S +  L V         SP +V V  G  A
Sbjct: 80  FFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPA 139

Query: 311 RFTCTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
              C    G PEP++ W  +G R        +++     +  G   L ++ T K+D+   
Sbjct: 140 VMECMPPRGHPEPSVSWKKDGVRL-------KEEEGRITIRGGK--LMMSHTFKSDA-GM 189

Query: 370 IVCSAVNYAGS-SFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428
            VC A N AG       KL V    +RP       P NQ +   +   FPC     P P 
Sbjct: 190 YVCVASNMAGERESGAAKLVVL---ERPS--FLRRPVNQVVLAGAPVDFPCEVQGDPPPR 244

Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
           + W  E +  +   R  + +D +L +  +   D GTYTCVA +  G+   SG+L+V  P
Sbjct: 245 LRWRKE-DGELPTGRYEIQSDHSLQIGRVSAEDEGTYTCVAENSVGRAEASGSLIVHVP 302



 Score = 62.9 bits (146), Expect = 5e-08
 Identities = 43/143 (30%), Positives = 67/143 (46%), Gaps = 20/143 (13%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
           E P  + +P++  V    P    C   G P P +RW K             LP  G + +
Sbjct: 212 ERPSFLRRPVNQVVLAGAPVDFPCEVQGDPPPRLRWRK---------EDGELPT-GRYEI 261

Query: 70  RATH----GRVHS-DAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESKQSAQGD 123
           ++ H    GRV + D G Y C A NS G A  S +  +HV     +   +P+ + +A GD
Sbjct: 262 QSDHSLQIGRVSAEDEGTYTCVAENSVGRAEASGSLIVHVP---PQLVTQPQDQMAAPGD 318

Query: 124 TVVLECLPPRGSPEPNVYWKKNG 146
           +V  +C   +G+P P ++W+K G
Sbjct: 319 SVAFQC-ETKGNPPPAIFWQKEG 340


>UniRef50_Q172F7 Cluster: Roundabout, putative; n=2; Culicidae|Rep:
           Roundabout, putative - Aedes aegypti (Yellowfever
           mosquito)
          Length = 1086

 Score =  268 bits (657), Expect = 6e-70
 Identities = 131/315 (41%), Positives = 179/315 (56%), Gaps = 3/315 (0%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P I E P D   A+ +P TLNC+A G P P I WY  GV +     R +LP G LFFL+ 
Sbjct: 16  PRIQEHPADAVAAKEEPLTLNCKAVGRPPPDINWYHNGVPLGPSDRRVVLPEGSLFFLKV 75

Query: 72  THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
              +   DAGVY CEA NS G A SRNATL +A+L++EFR  P+   +  G  V+L C P
Sbjct: 76  MQNKREQDAGVYHCEAHNSAGVAVSRNATLQIAMLKDEFRAMPKDTVALVGGPVILNCTP 135

Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
           PRG PEP+V W K+G+ L   G  R+ +VD G+L+I + +  D G+Y+C A++ AGT+ +
Sbjct: 136 PRGIPEPSVLWIKDGKLLDISG-KRLSMVDSGSLMISEIQPNDTGKYECSAQSMAGTKTT 194

Query: 192 AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
             A LK+   P ++  P D     G      C + GDP P V WR+ +  G +P GR + 
Sbjct: 195 PPAYLKVLAPPTIVKSPHDTEVLEGEGFDLPCELAGDPKPVVTWRKES--GRLPEGRSRK 252

Query: 252 LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVAR 311
           L D +LR+++    DEG+Y CE  N  G V+ S YL VY+ P+   +P  V +  G    
Sbjct: 253 LLDNTLRIEDARQDDEGKYICEGHNEGGNVTISVYLYVYEAPTFMEAPVDVVIREGEGIT 312

Query: 312 FTCTATGRPEPTMFW 326
             C A GRP   +FW
Sbjct: 313 LPCRAKGRPGVRIFW 327



 Score =  115 bits (277), Expect = 7e-24
 Identities = 99/335 (29%), Positives = 138/335 (41%), Gaps = 24/335 (7%)

Query: 103 VAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG 162
           VA LR   +  P    +A+ + + L C    G P P++ W  NG  L    D R+ L +G
Sbjct: 11  VAQLRPRIQEHPADAVAAKEEPLTLNCKAV-GRPPPDINWYHNGVPL-GPSDRRVVLPEG 68

Query: 163 GNL---VIQDARQTDAGRYQCIARNAAGTRESAIATLKIH-IKPYLITGPEDVVAQTGSS 218
                 V+Q+ R+ DAG Y C A N+AG   S  ATL+I  +K      P+D VA  G  
Sbjct: 69  SLFFLKVMQNKREQDAGVYHCEAHNSAGVAVSRNATLQIAMLKDEFRAMPKDTVALVGGP 128

Query: 219 VTFQCRVG-GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENS 277
           V   C    G P P VLW +     ++   R+ ++D GSL +  +   D G+Y C A++ 
Sbjct: 129 VILNCTPPRGIPEPSVLWIKDGKLLDISGKRLSMVDSGSLMISEIQPNDTGKYECSAQSM 188

Query: 278 VGA-VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF 336
            G   +   YL V  PP+I  SP+   V  G      C   G P+P + W  E  R  + 
Sbjct: 189 AGTKTTPPAYLKVLAPPTIVKSPHDTEVLEGEGFDLPCELAGDPKPVVTWRKESGR--LP 246

Query: 337 PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP 396
            G SR     T        L I D  + D     +C   N  G+  +   L V       
Sbjct: 247 EGRSRKLLDNT--------LRIEDA-RQDDEGKYICEGHNEGGNVTISVYLYVYE----- 292

Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431
            P     P +  +        PC A   P   I W
Sbjct: 293 APTFMEAPVDVVIREGEGITLPCRAKGRPGVRIFW 327



 Score =  103 bits (247), Expect = 3e-20
 Identities = 67/281 (23%), Positives = 136/281 (48%), Gaps = 21/281 (7%)

Query: 631 LTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFR----PLDNITIEYEMKTILHS 686
           +++  + L     I + +I + W++ +      L +Y+R    P+DN       ++ + +
Sbjct: 497 VSEQFIVLNNVFTISASSIGISWDVTDSATKMPLRMYYRVASEPMDNFIYNSTFESQVTT 556

Query: 687 NDVSGFEITSLRKYTKYEFFL-IPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNT 745
           +++    +  LR +T+YE F  IP  +   G  SN R  +TLD  P  PP ++ + ++NT
Sbjct: 557 SNLKELTLNDLRPFTEYEIFASIP--EGLSGSVSNIRRGKTLDGPPSAPPTDVRVGVINT 614

Query: 746 TTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVS 805
           T   ++WSPP + + NG +TGY + +           + +N+T     S+++ +LT G  
Sbjct: 615 TAAFVRWSPPPVHMLNGELTGYKIQIKSNATNKVLGQMILNSTTQ---SVVINSLTPGAM 671

Query: 806 YSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETWFYFLI 865
           Y  ++A+ T  G+GP+S     ++D +++      RYP           + M +W     
Sbjct: 672 YIAKVASLTSGGIGPYSLPTSLHMDPQNI-----VRYPKTDPTP----SYWMSSWMSGT- 721

Query: 866 GAIVLFKIIVIAGIIYVRKYNIFAKKSALPNIYDSNGTSLV 906
            A+V+  + +I G I+   + +  K+S   +    + T+++
Sbjct: 722 -ALVILCVCLIGGAIFAIFWTVRKKQSVKASYPGPSVTTII 761



 Score = 88.6 bits (210), Expect = 9e-16
 Identities = 69/222 (31%), Positives = 97/222 (43%), Gaps = 12/222 (5%)

Query: 18  PLDVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGR 75
           P D       P  LNC    G P P++ W K G L+ +S    S++ +G L         
Sbjct: 118 PKDTVALVGGPVILNCTPPRGIPEPSVLWIKDGKLLDISGKRLSMVDSGSLMISEIQP-- 175

Query: 76  VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGS 135
             +D G Y C A +  GT  +  A L V       +  P   +  +G+   L C    G 
Sbjct: 176 --NDTGKYECSAQSMAGTKTTPPAYLKVLAPPTIVK-SPHDTEVLEGEGFDLPC-ELAGD 231

Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195
           P+P V W+K    L  +G SR  L+D   L I+DARQ D G+Y C   N  G    ++  
Sbjct: 232 PKPVVTWRKESGRLP-EGRSRK-LLDN-TLRIEDARQDDEGKYICEGHNEGGNVTISVY- 287

Query: 196 LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
           L ++  P  +  P DVV + G  +T  CR  G P   + W R
Sbjct: 288 LYVYEAPTFMEAPVDVVIREGEGITLPCRAKGRPGVRIFWDR 329



 Score = 81.8 bits (193), Expect = 1e-13
 Identities = 80/305 (26%), Positives = 126/305 (41%), Gaps = 31/305 (10%)

Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLR- 258
           ++P +   P D VA     +T  C+  G P PD+ W  + G    P  R  VL +GSL  
Sbjct: 14  LRPRIQEHPADAVAAKEEPLTLNCKAVGRPPPDINWYHN-GVPLGPSDRRVVLPEGSLFF 72

Query: 259 ---LDNVILADEGEYSCEAENSVG-AVSASGYLTVYD-PPSINLSPNSVNVESGNVARFT 313
              + N    D G Y CEA NS G AVS +  L +          P       G      
Sbjct: 73  LKVMQNKREQDAGVYHCEAHNSAGVAVSRNATLQIAMLKDEFRAMPKDTVALVGGPVILN 132

Query: 314 CTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
           CT   G PEP++ W  +G + +   G       + ++   ++ +  NDT K +      C
Sbjct: 133 CTPPRGIPEPSVLWIKDG-KLLDISGKRLSMVDSGSLM--ISEIQPNDTGKYE------C 183

Query: 373 SAVNYAGSSFVR-GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431
           SA + AG+       L V +    PP I+ +    + L  +   + PC     P+P++ W
Sbjct: 184 SAQSMAGTKTTPPAYLKVLA----PPTIVKSPHDTEVLEGEGFDL-PCELAGDPKPVVTW 238

Query: 432 YFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK-------YVWSGALLV 484
             E   L +   R +  D TL ++D  + D G Y C   +  G        YV+     +
Sbjct: 239 RKESGRLPEGRSRKLL-DNTLRIEDARQDDEGKYICEGHNEGGNVTISVYLYVYEAPTFM 297

Query: 485 DSPIN 489
           ++P++
Sbjct: 298 EAPVD 302



 Score = 41.1 bits (92), Expect = 0.18
 Identities = 30/113 (26%), Positives = 47/113 (41%), Gaps = 4/113 (3%)

Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTL----V 453
           P I   P++     +      C A+  P P I WY  G  L  + RR V  +G+L    V
Sbjct: 16  PRIQEHPADAVAAKEEPLTLNCKAVGRPPPDINWYHNGVPLGPSDRRVVLPEGSLFFLKV 75

Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGP 506
           +++  + D+G Y C A +  G  V   A L  + +           V+ + GP
Sbjct: 76  MQNKREQDAGVYHCEAHNSAGVAVSRNATLQIAMLKDEFRAMPKDTVALVGGP 128



 Score = 36.7 bits (81), Expect = 3.9
 Identities = 17/41 (41%), Positives = 22/41 (53%)

Query: 5   YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRW 45
           Y+   EAP  +E P+DV +   +  TL CRA G P   I W
Sbjct: 287 YLYVYEAPTFMEAPVDVVIREGEGITLPCRAKGRPGVRIFW 327


>UniRef50_UPI00006A0174 Cluster: Roundabout homolog 4 precursor
           (Magic roundabout).; n=1; Xenopus tropicalis|Rep:
           Roundabout homolog 4 precursor (Magic roundabout). -
           Xenopus tropicalis
          Length = 1082

 Score =  237 bits (580), Expect = 1e-60
 Identities = 126/287 (43%), Positives = 166/287 (57%), Gaps = 10/287 (3%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT----HRSI--LPAGG 65
           P IIE P D+ V + +PATL CRA G+P P I WY+ G  V + T     RS   LP G 
Sbjct: 11  PRIIEHPSDLFVKKDKPATLYCRAEGNPQPTIEWYRNGEHVETSTDDKTQRSYVQLPEGP 70

Query: 66  LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
           LFF      +  SD G+Y C A N  GTA SRNA+L+VA LR++FRL P     A G  +
Sbjct: 71  LFFFSLNQRKGKSDEGIYTCVARNHLGTAFSRNASLYVAALRDDFRLNPSDAVVAVGKQL 130

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
            +ECLPP+G PEPNV WKK+G  +  + ++  + +  G L I  A +TD+G Y C+A N 
Sbjct: 131 EIECLPPKGHPEPNVTWKKDG--IPINHNNSRYTISAGKLFIGKALKTDSGLYSCLASNQ 188

Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
            G RES  A + +  KP     P DV A+ GS+V F C   GDP P   W  S   G++P
Sbjct: 189 VGERESRAAKIVVLEKPMFTYKPSDVTAKFGSTVQFGCGAQGDPKPTFHW--SKENGDLP 246

Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
            GR ++ ++ +LR+ +V L D G+Y C A N +  VSA   LTV DP
Sbjct: 247 QGRYEITNENTLRIRSVTLYDSGKYICTAGNQLETVSAKALLTVQDP 293



 Score = 92.7 bits (220), Expect = 6e-17
 Identities = 61/207 (29%), Positives = 93/207 (44%), Gaps = 12/207 (5%)

Query: 134 GSPEPNVYWKKNGQTLLFDGDSR-----MHLVDGGNLVI---QDARQTDAGRYQCIARNA 185
           G+P+P + W +NG+ +    D +     + L +G        Q   ++D G Y C+ARN 
Sbjct: 36  GNPQPTIEWYRNGEHVETSTDDKTQRSYVQLPEGPLFFFSLNQRKGKSDEGIYTCVARNH 95

Query: 186 AGTRESAIATLKIH-IKPYLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGN 243
            GT  S  A+L +  ++      P D V   G  +  +C    G P P+V W++     N
Sbjct: 96  LGTAFSRNASLYVAALRDDFRLNPSDAVVAVGKQLEIECLPPKGHPEPNVTWKKDGIPIN 155

Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSV 302
               R  +   G L +   +  D G YSC A N VG   S +  + V + P     P+ V
Sbjct: 156 HNNSRYTI-SAGKLFIGKALKTDSGLYSCLASNQVGERESRAAKIVVLEKPMFTYKPSDV 214

Query: 303 NVESGNVARFTCTATGRPEPTMFWSVE 329
             + G+  +F C A G P+PT  WS E
Sbjct: 215 TAKFGSTVQFGCGAQGDPKPTFHWSKE 241



 Score = 78.2 bits (184), Expect = 1e-12
 Identities = 87/320 (27%), Positives = 141/320 (44%), Gaps = 24/320 (7%)

Query: 636 VELIEATPIDSKTIKLMWEILNFY-YLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEI 694
           V L   T + S ++ + W++L    + EG  +++R L +   E+   T    N+ S   I
Sbjct: 314 VHLDNITALPSASVYVHWQVLTESPFTEGYSVFYRTLSSTESEWTEWTKSRINEYSTV-I 372

Query: 695 TSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILN--TTTVHLKW 752
            SL +  KYEF + PF  K  G  SN +  +  ++VP+  P NI +  +     T+ + W
Sbjct: 373 PSLWRGQKYEFKIRPFAGKNYGPDSNIKHLRIPEEVPNIAPQNINVTAVEGGNGTIVVSW 432

Query: 753 SPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT-SLIMTNLTSGVSYSVQIA 811
            PP   + +  I GY V   W     N++    +  V + T SL +  L SG+ Y VQ+A
Sbjct: 433 EPPPKNIHSSNIKGYKV---WCF--ENETHPKADWIVDEETKSLEIPMLASGIKYQVQVA 487

Query: 812 AETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETWFYFLIGAIVLF 871
           A    G+G  S   Y  IDS  V    +    +  E+ +     V    F   +G +   
Sbjct: 488 AINDAGIGMPSIPKYIMIDSPEV--KEVKDENIYFELIL---QVVRHPAFIGTVGTVAWI 542

Query: 872 KIIVIAGIIYVRKYNIFAKK--SALPNI---YDSNGTSLVTQMNIKAAVSLSH--PLTSC 924
            ++V A  +  R    ++ K  S L N    + S  T +  +M+I  +  LSH     SC
Sbjct: 543 LLMVAAVYVCQRHSKRYSTKQHSILGNSLYRFASEDTIIKHRMDISDSPWLSHTWKSASC 602

Query: 925 YN--KNTVTKTESLLWMENQ 942
                +T++    LLW E +
Sbjct: 603 SRNYSSTISMNSQLLWSETK 622



 Score = 76.6 bits (180), Expect = 4e-12
 Identities = 83/301 (27%), Positives = 117/301 (38%), Gaps = 29/301 (9%)

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG----GGNMPLGRVKV-LDDGS 256
           P +I  P D+  +     T  CR  G+P P + W R+        +    R  V L +G 
Sbjct: 11  PRIIEHPSDLFVKKDKPATLYCRAEGNPQPTIEWYRNGEHVETSTDDKTQRSYVQLPEGP 70

Query: 257 LRLDNVIL----ADEGEYSCEAENSVGAV---SASGYLTVYDPPSINLSPNSVNVESGNV 309
           L   ++      +DEG Y+C A N +G     +AS Y+         L+P+   V  G  
Sbjct: 71  LFFFSLNQRKGKSDEGIYTCVARNHLGTAFSRNASLYVAALRD-DFRLNPSDAVVAVGKQ 129

Query: 310 ARFTCTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
               C    G PEP + W  +G    I    SR    A  +F G  +       K DS  
Sbjct: 130 LEIECLPPKGHPEPNVTWKKDG--IPINHNNSRYTISAGKLFIGKAL-------KTDS-G 179

Query: 369 TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428
              C A N  G    R    V  +     P+ T  PS+ T    S   F C A   P+P 
Sbjct: 180 LYSCLASNQVGERESRAAKIVVLEK----PMFTYKPSDVTAKFGSTVQFGCGAQGDPKPT 235

Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPI 488
             W  E   L Q  R  +TN+ TL ++ +   DSG Y C A ++         L V  P+
Sbjct: 236 FHWSKENGDLPQG-RYEITNENTLRIRSVTLYDSGKYICTAGNQLETVSAKALLTVQDPL 294

Query: 489 N 489
           +
Sbjct: 295 D 295



 Score = 64.1 bits (149), Expect = 2e-08
 Identities = 55/241 (22%), Positives = 94/241 (39%), Gaps = 12/241 (4%)

Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
           PP I   P+ + V+    A   C A G P+PT+ W   G            + +      
Sbjct: 10  PPRIIEHPSDLFVKKDKPATLYCRAEGNPQPTIEWYRNGEHVETSTDDKTQRSYVQLPEG 69

Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK---LTVTSDDDRPPPIITNGPSNQT 408
            +   ++N            C A N+ G++F R     +    DD R        PS+  
Sbjct: 70  PLFFFSLNQRKGKSDEGIYTCVARNHLGTAFSRNASLYVAALRDDFRL------NPSDAV 123

Query: 409 LPIKSMAVFPCTAICT-PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
           + +       C      PEP + W  +G  +  N+ R   + G L +    K+DSG Y+C
Sbjct: 124 VAVGKQLEIECLPPKGHPEPNVTWKKDGIPINHNNSRYTISAGKLFIGKALKTDSGLYSC 183

Query: 468 VASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527
           +AS++ G+     A +V   +   +  ++ +DV++  G   +       D   T  WS+ 
Sbjct: 184 LASNQVGERESRAAKIV--VLEKPMFTYKPSDVTAKFGSTVQFGCGAQGDPKPTFHWSKE 241

Query: 528 N 528
           N
Sbjct: 242 N 242


>UniRef50_Q71B05 Cluster: Roundabout-like protein 4; n=5; Danio
           rerio|Rep: Roundabout-like protein 4 - Danio rerio
           (Zebrafish) (Brachydanio rerio)
          Length = 1134

 Score =  227 bits (554), Expect = 2e-57
 Identities = 121/286 (42%), Positives = 157/286 (54%), Gaps = 10/286 (3%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-----THRSILPAGGL 66
           P I+  P DV V    PATL+CRA G+P P I+W + G  + +D     +   +LP G L
Sbjct: 71  PRIVHHPSDVVVRVGSPATLSCRAEGNPEPTIQWLRNGQPLDTDKMDAQSQPIVLPDGSL 130

Query: 67  FFLRATHGRV-HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
           FF     GR   S   VY C A NS G A SRNA+LH+A LRE+FR++P   + A G+  
Sbjct: 131 FFFSVVPGRKGQSHEAVYACIAHNSIGNATSRNASLHIAALREDFRVQPSDVEVAIGEMA 190

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
            + C PP G PEPNV W+K+G  +L +  +  +    G L+I  A++ D+G Y CIA N 
Sbjct: 191 TINCSPPVGHPEPNVTWRKDG--ILINSSNEHYTELKGKLIIAPAQKNDSGVYSCIASNM 248

Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
            G RES  A L +  KP L+  PEDV  Q G S  F C   GDP+P + W R    G +P
Sbjct: 249 IGVRESRAARLSVLAKPVLLRKPEDVSVQLGESAQFFCEADGDPMPSIEWSREQ--GPLP 306

Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
            GR  +  D SL++  V   D G YSC  EN +G   AS  L V D
Sbjct: 307 NGRYLINPDHSLQIHYVTAQDMGRYSCTVENKLGVSVASAQLLVED 352



 Score = 94.7 bits (225), Expect = 1e-17
 Identities = 123/430 (28%), Positives = 181/430 (42%), Gaps = 52/430 (12%)

Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
           R+ A  R+ +    +I++ P ++  P DVV + GS  T  CR  G+P P + W R+    
Sbjct: 53  RDRAHRRKGSRLVSEINL-PRIVHHPSDVVVRVGSPATLSCRAEGNPEPTIQWLRNG--- 108

Query: 243 NMPLGRVK--------VLDDGSLRLDNVILADEGE-----YSCEAENSVG-AVSASGYLT 288
             PL   K        VL DGSL   +V+   +G+     Y+C A NS+G A S +  L 
Sbjct: 109 -QPLDTDKMDAQSQPIVLPDGSLFFFSVVPGRKGQSHEAVYACIAHNSIGNATSRNASLH 167

Query: 289 VYD-PPSINLSPNSVNVESGNVARFTCTA-TGRPEPTMFWSVEGNRTIIFPGMSRDKYHA 346
           +        + P+ V V  G +A   C+   G PEP + W  +G    I    S + Y  
Sbjct: 168 IAALREDFRVQPSDVEVAIGEMATINCSPPVGHPEPNVTWRKDG----ILINSSNEHY-- 221

Query: 347 TAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG-KLTVTSDDDRPPPIITNGPS 405
                G   L I    KNDS     C A N  G    R  +L+V +      P++   P 
Sbjct: 222 -TELKGK--LIIAPAQKNDS-GVYSCIASNMIGVRESRAARLSVLAK-----PVLLRKPE 272

Query: 406 NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465
           + ++ +   A F C A   P P I W  E +  + N R  +  D +L +  +   D G Y
Sbjct: 273 DVSVQLGESAQFFCEADGDPMPSIEWSRE-QGPLPNGRYLINPDHSLQIHYVTAQDMGRY 331

Query: 466 TCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWS 525
           +C   ++ G  V S  LLV+      +      ++S+L     +    NVT  S   + S
Sbjct: 332 SCTVENKLGVSVASAQLLVEDAGGTRLRDLH-KELSAL-----RVSLENVTVMSTASNMS 385

Query: 526 QNN-KIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQ--THYVVKSLIPGIT 582
           Q   K+ S     + +E F  E L  +  P +S  W   A+RV Q   H  V  L  G  
Sbjct: 386 QVMWKLQSFGSQPHYLEGF--EVLYRSLLPASS-DWT--AQRVPQPSLHTHVGPLKRGYK 440

Query: 583 YMFIVRTENS 592
           Y F VR   S
Sbjct: 441 YEFKVRPYGS 450



 Score = 89.4 bits (212), Expect = 5e-16
 Identities = 76/243 (31%), Positives = 105/243 (43%), Gaps = 18/243 (7%)

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTL---LFDGDSRMHLVDGGNL----VIQDAR-QT 173
           G    L C    G+PEP + W +NGQ L     D  S+  ++  G+L    V+   + Q+
Sbjct: 85  GSPATLSCRA-EGNPEPTIQWLRNGQPLDTDKMDAQSQPIVLPDGSLFFFSVVPGRKGQS 143

Query: 174 DAGRYQCIARNAAGTRESAIATLKIH-IKPYLITGPEDVVAQTGSSVTFQCRVG-GDPLP 231
               Y CIA N+ G   S  A+L I  ++      P DV    G   T  C    G P P
Sbjct: 144 HEAVYACIAHNSIGNATSRNASLHIAALREDFRVQPSDVEVAIGEMATINCSPPVGHPEP 203

Query: 232 DVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVY 290
           +V WR+     N        L  G L +      D G YSC A N +G   S +  L+V 
Sbjct: 204 NVTWRKDGILINSSNEHYTELK-GKLIIAPAQKNDSGVYSCIASNMIGVRESRAARLSVL 262

Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVE-----GNRTIIFPGMSRDKYH 345
             P +   P  V+V+ G  A+F C A G P P++ WS E       R +I P  S   ++
Sbjct: 263 AKPVLLRKPEDVSVQLGESAQFFCEADGDPMPSIEWSREQGPLPNGRYLINPDHSLQIHY 322

Query: 346 ATA 348
            TA
Sbjct: 323 VTA 325



 Score = 72.1 bits (169), Expect = 8e-11
 Identities = 63/240 (26%), Positives = 106/240 (44%), Gaps = 20/240 (8%)

Query: 646 SKTIKLMWEILNF----YYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYT 701
           S   ++MW++ +F    +YLEG  + +R L   + ++  + +   +  +   +  L++  
Sbjct: 382 SNMSQVMWKLQSFGSQPHYLEGFEVLYRSLLPASSDWTAQRVPQPSLHT--HVGPLKRGY 439

Query: 702 KYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPP--INIEMFILNTTTVHLKWSPPELQL 759
           KYEF + P+     G+ SN+R  +  + VP   P  ++I M      TVHL W PP    
Sbjct: 440 KYEFKVRPYGSSLYGRESNTRHLRVPEIVPSAAPQDVSITMPAERNDTVHLSWEPPPHDA 499

Query: 760 QNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT-SLIMTNLTSGVSYSVQIAAETIIGL 818
            NGII GY V   W     ++   + N TV   T S+ +  L     Y V +AA    G+
Sbjct: 500 HNGIIQGYQV---W--CVESEEQTSFNWTVDSGTHSIEIVTLLPSRLYWVSVAAVNGAGV 554

Query: 819 GPFSQKVYFNIDSR------SVGLDLLSRYPMNGEVSIVAGDFVMETWFYFLIGAIVLFK 872
           G  S      I+SR        G+  +S +    +  +  G      W   +I A+ L++
Sbjct: 555 GVQSDPYKLLIESRLEATPYQTGILSMSHFVSVIKEPVFIGSVGTLLWCVLMITAVFLYR 614


>UniRef50_Q4SCT9 Cluster: Chromosome 7 SCAF14650, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 7
           SCAF14650, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 1450

 Score =  219 bits (536), Expect = 3e-55
 Identities = 139/443 (31%), Positives = 227/443 (51%), Gaps = 27/443 (6%)

Query: 394 DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGTL 452
           D PPP+I  GP NQT+P+ S  V  C A+  P P+I W  +G  L   + R ++T+ G+L
Sbjct: 317 DHPPPVIKRGPLNQTVPVDSTVVLSCHAVGIPPPVIHWKKDGVVLSPADSRMSITDMGSL 376

Query: 453 VLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPIT 512
            ++     D+G+YTCVA+S +G+  W+  L V+  +         AD++ +PG P+KP  
Sbjct: 377 EIRYAKLGDTGSYTCVATSPNGEASWTAHLQVEGRVWSCCSLRPPADLNLIPGAPSKPEV 436

Query: 513 HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHY 572
            ++T TSV L+W  N   G++    Y +E FS  TL           WV +   V    +
Sbjct: 437 TDITRTSVMLTWKSNQSSGAAPT-SYLIEAFSY-TLGSR--------WVTLVEHVKTDTF 486

Query: 573 VVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILT 632
           V+K+L P   Y+F+VR  NSHG+S PSP++DSV   D  +++    GV +   +    L 
Sbjct: 487 VLKNLRPATVYLFMVRAVNSHGISDPSPITDSVRTQDSPSTI---PGVDH--RHIQKELG 541

Query: 633 DHIVELIEATPIDSKTIKLMWEI-LNFYYLEGLFIYFRP-LDNITIEYEMKTI-LHSNDV 689
           D +V L   T + S  ++L W +     Y++G  +++RP  D+   E +   + + +   
Sbjct: 542 DVVVHLHTPTIVSSSAVRLQWVVEQQSPYIQGYKVFYRPSADHGQPEGQWSIVEVQAPRD 601

Query: 690 SGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPP--INIEMFILNTTT 747
            G  I  L+  + YEF + PF+ +F+G  S  +V +T +D P   P  + +    +N T 
Sbjct: 602 DGVVIGQLKGGSIYEFKVRPFFDEFQGADSEVKVVRTSEDAPKRAPQDVTVTKSDVNGTA 661

Query: 748 VHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT-SLIMTNLTSGVSY 806
           + + W PP      G I  Y +   W     N+S   +N +V  +T S+++ +L  G+ Y
Sbjct: 662 ILVAWKPPLEWEDTGRIQEYKI---W--CLGNESRYHVNQSVDGSTLSVVIPSLAPGIRY 716

Query: 807 SVQIAAETIIGLGPFSQKVYFNI 829
           SV++AA    G G  S   +F +
Sbjct: 717 SVEVAASNGAGPGVKSDATFFQL 739



 Score =  211 bits (516), Expect = 8e-53
 Identities = 109/287 (37%), Positives = 156/287 (54%), Gaps = 6/287 (2%)

Query: 104 AVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG 163
           ++LR++FR  P     A G+  VLEC PPRG PEP + W+++G  L  D D R+  +  G
Sbjct: 3   SILRDDFRQNPVDVMVAVGEPAVLECQPPRGHPEPTISWRRDGANLN-DKDERI-TIRSG 60

Query: 164 NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223
            L+I + +++DAG+Y C+  N  G RES IA L +  +P  +  P  VV     SV F C
Sbjct: 61  KLMITNTKKSDAGKYICVGTNMVGERESEIAELTVLERPTFVKRPRSVVVLAEESVKFHC 120

Query: 224 RVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSA 283
            V GDP+P V WR+     ++P GR ++LDD +L +  V   DEG Y+C  EN VG   A
Sbjct: 121 VVQGDPVPTVRWRKD--DSDLPKGRFEILDDHTLNIRQVTSVDEGSYTCVVENMVGKSEA 178

Query: 284 SGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDK 343
           S  LTV+ PP+  + P +     G +  F C ATG P+P +FW  EG+ +++F       
Sbjct: 179 SATLTVHVPPAFAVRPRNQEAAVGRIVTFQCEATGNPQPAIFWQKEGSESLLFSYQPPQP 238

Query: 344 YHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT 390
           +   +V      LTI +   +DS     C A+N AGS   +  L VT
Sbjct: 239 FSRLSV-SQTGSLTITNVQHSDS-GFYSCQALNIAGSVITKALLEVT 283



 Score =  139 bits (336), Expect = 5e-31
 Identities = 92/284 (32%), Positives = 126/284 (44%), Gaps = 18/284 (6%)

Query: 16  EQPLDVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74
           + P+DV VA  +PA L C+   G P P I W + G  +     R  + +G L        
Sbjct: 11  QNPVDVMVAVGEPAVLECQPPRGHPEPTISWRRDGANLNDKDERITIRSGKLMITNTKK- 69

Query: 75  RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRG 134
              SDAG Y C  TN  G   S  A L V + R  F   P S      ++V   C+  +G
Sbjct: 70  ---SDAGKYICVGTNMVGERESEIAELTV-LERPTFVKRPRSVVVLAEESVKFHCVV-QG 124

Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194
            P P V W+K+   L      R  ++D   L I+     D G Y C+  N  G  E++ A
Sbjct: 125 DPVPTVRWRKDDSDL---PKGRFEILDDHTLNIRQVTSVDEGSYTCVVENMVGKSEAS-A 180

Query: 195 TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM-------PLG 247
           TL +H+ P     P +  A  G  VTFQC   G+P P + W++      +       P  
Sbjct: 181 TLTVHVPPAFAVRPRNQEAAVGRIVTFQCEATGNPQPAIFWQKEGSESLLFSYQPPQPFS 240

Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
           R+ V   GSL + NV  +D G YSC+A N  G+V     L V D
Sbjct: 241 RLSVSQTGSLTITNVQHSDSGFYSCQALNIAGSVITKALLEVTD 284



 Score = 97.1 bits (231), Expect = 3e-18
 Identities = 81/287 (28%), Positives = 119/287 (41%), Gaps = 27/287 (9%)

Query: 208 PEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILAD 266
           P DV+   G     +C+   G P P + WRR     N    R+ +   G L + N   +D
Sbjct: 13  PVDVMVAVGEPAVLECQPPRGHPEPTISWRRDGANLNDKDERITIRS-GKLMITNTKKSD 71

Query: 267 EGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325
            G+Y C   N VG   S    LTV + P+    P SV V +    +F C   G P PT+ 
Sbjct: 72  AGKYICVGTNMVGERESEIAELTVLERPTFVKRPRSVVVLAEESVKFHCVVQGDPVPTVR 131

Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385
           W  + +       + + ++    + D  T L I      D   +  C   N  G S    
Sbjct: 132 WRKDDS------DLPKGRFE---ILDDHT-LNIRQVTSVDE-GSYTCVVENMVGKSEASA 180

Query: 386 KLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG-EALIQNH-- 442
            LTV       PP     P NQ   +  +  F C A   P+P I W  EG E+L+ ++  
Sbjct: 181 TLTV-----HVPPAFAVRPRNQEAAVGRIVTFQCEATGNPQPAIFWQKEGSESLLFSYQP 235

Query: 443 -----RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
                R +V+  G+L + ++  SDSG Y+C A +  G  +    L V
Sbjct: 236 PQPFSRLSVSQTGSLTITNVQHSDSGFYSCQALNIAGSVITKALLEV 282



 Score = 76.2 bits (179), Expect = 5e-12
 Identities = 55/185 (29%), Positives = 87/185 (47%), Gaps = 14/185 (7%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
           E P  +++P  V V   +    +C   G P P +RW K    +       IL    L   
Sbjct: 97  ERPTFVKRPRSVVVLAEESVKFHCVVQGDPVPTVRWRKDDSDLPKGRF-EILDDHTLNIR 155

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
           + T      D G Y C   N  G + + +ATL V V    F + P ++++A G  V  +C
Sbjct: 156 QVT----SVDEGSYTCVVENMVGKSEA-SATLTVHV-PPAFAVRPRNQEAAVGRIVTFQC 209

Query: 130 LPPRGSPEPNVYWKKNG-QTLLFDGD-----SRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
               G+P+P ++W+K G ++LLF        SR+ +   G+L I + + +D+G Y C A 
Sbjct: 210 -EATGNPQPAIFWQKEGSESLLFSYQPPQPFSRLSVSQTGSLTITNVQHSDSGFYSCQAL 268

Query: 184 NAAGT 188
           N AG+
Sbjct: 269 NIAGS 273



 Score = 52.4 bits (120), Expect = 7e-05
 Identities = 50/192 (26%), Positives = 74/192 (38%), Gaps = 18/192 (9%)

Query: 298 SPNSVNVESGNVARFTCTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
           +P  V V  G  A   C    G PEPT+ W  +G           DK     +  G  ++
Sbjct: 12  NPVDVMVAVGEPAVLECQPPRGHPEPTISWRRDGANL-------NDKDERITIRSGKLMI 64

Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVR-GKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
           T  +T K+D+    +C   N  G       +LTV        P     P +  +  +   
Sbjct: 65  T--NTKKSDA-GKYICVGTNMVGERESEIAELTVLER-----PTFVKRPRSVVVLAEESV 116

Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
            F C     P P + W  +   L +  R  + +D TL ++ +   D G+YTCV  +  GK
Sbjct: 117 KFHCVVQGDPVPTVRWRKDDSDLPKG-RFEILDDHTLNIRQVTSVDEGSYTCVVENMVGK 175

Query: 476 YVWSGALLVDSP 487
              S  L V  P
Sbjct: 176 SEASATLTVHVP 187



 Score = 52.4 bits (120), Expect = 7e-05
 Identities = 28/64 (43%), Positives = 38/64 (59%), Gaps = 2/64 (3%)

Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
           TVVL C    G P P ++WKK+G  +L   DSRM + D G+L I+ A+  D G Y C+A 
Sbjct: 337 TVVLSCHAV-GIPPPVIHWKKDG-VVLSPADSRMSITDMGSLEIRYAKLGDTGSYTCVAT 394

Query: 184 NAAG 187
           +  G
Sbjct: 395 SPNG 398



 Score = 47.6 bits (108), Expect = 0.002
 Identities = 33/84 (39%), Positives = 38/84 (45%), Gaps = 5/84 (5%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLFFLR 70
           P I   PL+ TV       L+C A G P P I W K G VL  +D+  SI   G L    
Sbjct: 321 PVIKRGPLNQTVPVDSTVVLSCHAVGIPPPVIHWKKDGVVLSPADSRMSITDMGSLEIRY 380

Query: 71  ATHGRVHSDAGVYWCEATNSYGTA 94
           A  G    D G Y C AT+  G A
Sbjct: 381 AKLG----DTGSYTCVATSPNGEA 400



 Score = 46.8 bits (106), Expect = 0.004
 Identities = 26/91 (28%), Positives = 40/91 (43%)

Query: 199 HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLR 258
           H  P +  GP +      S+V   C   G P P + W++     +    R+ + D GSL 
Sbjct: 318 HPPPVIKRGPLNQTVPVDSTVVLSCHAVGIPPPVIHWKKDGVVLSPADSRMSITDMGSLE 377

Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTV 289
           +    L D G Y+C A +  G  S + +L V
Sbjct: 378 IRYAKLGDTGSYTCVATSPNGEASWTAHLQV 408


>UniRef50_UPI000065EA6D Cluster: Homolog of Brachydanio rerio
           "Roundabout-like protein 4.; n=1; Takifugu rubripes|Rep:
           Homolog of Brachydanio rerio "Roundabout-like protein 4.
           - Takifugu rubripes
          Length = 1100

 Score =  219 bits (534), Expect = 5e-55
 Identities = 122/290 (42%), Positives = 163/290 (56%), Gaps = 10/290 (3%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSI----LPAGG 65
           AP I+  P DV V    PA L+CRA GSP  ++ W + G  L +S     +    LP G 
Sbjct: 71  APSIVHHPSDVVVKPGNPAQLSCRAEGSPQVSLEWLQNGQPLQMSKADGQMQPIMLPEGS 130

Query: 66  LFFLRATHG-RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
           LFFL    G R  S  GVY C A N+ GTA SRNA+L +AVL+EEF ++P   + A+G+ 
Sbjct: 131 LFFLSVGEGPRGPSHEGVYACVARNAVGTAISRNASLRIAVLQEEFHVQPSDVEVAEGEV 190

Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
            VL C PP G PEPNV WKK+G  +  + D    ++  G L++  A + ++G Y C+A N
Sbjct: 191 AVLNCGPPTGRPEPNVLWKKDGVPVNIN-DPHFTVL-SGKLIVAPAEKQNSGSYVCVATN 248

Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
             G RES  A L +  KP L+  PE+V  + G S  F C+  GDP P V+W R    G +
Sbjct: 249 TVGVRESRAARLSVLAKPTLLLKPENVSVKLGESAQFYCQAKGDPPPTVVWSREQ--GPL 306

Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
           P GR  V  + +L++  V   D G Y+C A N VG V+AS  L V + PS
Sbjct: 307 PNGRYLVNPNQTLQIHYVTAQDAGLYTCTAANDVGVVTASAQLLVEEAPS 356



 Score = 97.9 bits (233), Expect = 1e-18
 Identities = 79/256 (30%), Positives = 117/256 (45%), Gaps = 19/256 (7%)

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLF---DGDSRMHLVDGGNLVIQDARQ-----T 173
           G+   L C    GSP+ ++ W +NGQ L     DG  +  ++  G+L      +     +
Sbjct: 86  GNPAQLSCRA-EGSPQVSLEWLQNGQPLQMSKADGQMQPIMLPEGSLFFLSVGEGPRGPS 144

Query: 174 DAGRYQCIARNAAGTRESAIATLKIHI-KPYLITGPEDVVAQTGSSVTFQCRVG-GDPLP 231
             G Y C+ARNA GT  S  A+L+I + +      P DV    G      C    G P P
Sbjct: 145 HEGVYACVARNAVGTAISRNASLRIAVLQEEFHVQPSDVEVAEGEVAVLNCGPPTGRPEP 204

Query: 232 DVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVY 290
           +VLW++     N+      VL  G L +      + G Y C A N+VG   S +  L+V 
Sbjct: 205 NVLWKKDGVPVNINDPHFTVLS-GKLIVAPAEKQNSGSYVCVATNTVGVRESRAARLSVL 263

Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVE-----GNRTIIFPGMSRDKYH 345
             P++ L P +V+V+ G  A+F C A G P PT+ WS E       R ++ P  +   ++
Sbjct: 264 AKPTLLLKPENVSVKLGESAQFYCQAKGDPPPTVVWSREQGPLPNGRYLVNPNQTLQIHY 323

Query: 346 ATAVFDGV-TVLTIND 360
            TA   G+ T    ND
Sbjct: 324 VTAQDAGLYTCTAAND 339



 Score = 90.6 bits (215), Expect = 2e-16
 Identities = 89/299 (29%), Positives = 134/299 (44%), Gaps = 29/299 (9%)

Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL--GRVK--VLDDG 255
           I P ++  P DVV + G+     CR  G P   + W ++     M    G+++  +L +G
Sbjct: 70  IAPSIVHHPSDVVVKPGNPAQLSCRAEGSPQVSLEWLQNGQPLQMSKADGQMQPIMLPEG 129

Query: 256 SLRLDNV-----ILADEGEYSCEAENSVG-AVSASGYLTV-YDPPSINLSPNSVNVESGN 308
           SL   +V       + EG Y+C A N+VG A+S +  L +       ++ P+ V V  G 
Sbjct: 130 SLFFLSVGEGPRGPSHEGVYACVARNAVGTAISRNASLRIAVLQEEFHVQPSDVEVAEGE 189

Query: 309 VARFTC-TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
           VA   C   TGRPEP + W  +G      P    D  H T V  G   L +   +K +S 
Sbjct: 190 VAVLNCGPPTGRPEPNVLWKKDG-----VPVNINDP-HFT-VLSG--KLIVAPAEKQNS- 239

Query: 368 NTIVCSAVNYAGSSFVR-GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
            + VC A N  G    R  +L+V +      P +   P N ++ +   A F C A   P 
Sbjct: 240 GSYVCVATNTVGVRESRAARLSVLA-----KPTLLLKPENVSVKLGESAQFYCQAKGDPP 294

Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485
           P + W  E +  + N R  V  + TL +  +   D+G YTC A++  G    S  LLV+
Sbjct: 295 PTVVWSRE-QGPLPNGRYLVNPNQTLQIHYVTAQDAGLYTCTAANDVGVVTASAQLLVE 352



 Score = 62.1 bits (144), Expect = 9e-08
 Identities = 43/163 (26%), Positives = 74/163 (45%), Gaps = 8/163 (4%)

Query: 659 YYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKP 718
           +YL+G  + +R L   + ++  K +   +      +  L++  KYEF + P+     G+ 
Sbjct: 400 HYLDGFEVLYRSLLPASSDWAAKKVTMPSFQC--HLGPLKRGFKYEFKVRPYGSNLYGRE 457

Query: 719 SNSRVAQTLDDVPDGPP--INIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDV 776
           SN++  +  + VP   P  ++I +      T+HL W PP L   NGI+ GY V   W  V
Sbjct: 458 SNTQHLRVPETVPSASPQTVSISVSRQQNNTIHLSWEPPPLDTHNGILQGYQV---WC-V 513

Query: 777 PANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819
            + +      T       L ++ L  G  Y + +AA    G+G
Sbjct: 514 ESEEERYQNWTVNSSQQKLDISALKPGKQYWITVAAVNGAGVG 556


>UniRef50_Q96RW7 Cluster: Hemicentin-1 precursor; n=40; Eumetazoa|Rep:
            Hemicentin-1 precursor - Homo sapiens (Human)
          Length = 5635

 Score =  206 bits (502), Expect = 4e-51
 Identities = 153/481 (31%), Positives = 219/481 (45%), Gaps = 30/481 (6%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFF 68
            E P I  QP ++ V  + P  L C A G+PSP I W K G+ V  S  + ++LP+GGL  
Sbjct: 3986 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQI 4045

Query: 69   LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS--AQGDTVV 126
             RA    V  DAG Y C A N  GTA  +   L+V V      + P  K+   A    + 
Sbjct: 4046 SRA----VREDAGTYMCVAQNPAGTALGK-IKLNVQVPPV---ISPHLKEYVIAVDKPIT 4097

Query: 127  LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
            L C    G P P++ W K+G+ ++     R  ++  G+L I   +  DAG Y C+A N A
Sbjct: 4098 LSC-EADGLPPPDITWHKDGRAIV--ESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVA 4154

Query: 187  GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
            G+  S    L +H+ P + +          S     C   G P P + W++        L
Sbjct: 4155 GS-SSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLL 4213

Query: 247  GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
            G+      G L L+NV+L D G Y+C A N+ G  + +  LTV+  P+    P  V++  
Sbjct: 4214 GKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNK 4273

Query: 307  GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
            G   R +C ATG P P + W+   N   I P       H  +V +G + L I    K DS
Sbjct: 4274 GEQLRLSCKATGIPLPKLTWTFNNN---IIPA------HFDSV-NGHSELVIERVSKEDS 4323

Query: 367  RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
              T VC+A N  G     G + V      PP    + PSN   P+   A+  C     P 
Sbjct: 4324 -GTYVCTAENSVGFVKAIGFVYVKE----PPVFKGDYPSNWIEPLGGNAILNCEVKGDPT 4378

Query: 427  PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
            P I W  +G  +  +HR     +G+L +      D+G YTCVA++  G    S +L + S
Sbjct: 4379 PTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQS 4438

Query: 487  P 487
            P
Sbjct: 4439 P 4439



 Score =  187 bits (456), Expect = 1e-45
 Identities = 147/478 (30%), Positives = 210/478 (43%), Gaps = 28/478 (5%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV--SDTHRSILPAGGLFFL 69
            P I ++P D  V +H PA + C A G P P+I W K G+ ++   D +R IL +G +  L
Sbjct: 3897 PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYR-ILSSGAIEIL 3955

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
             AT     + AG Y C A N+ G+A  R+ TLHV       + +P        + ++L C
Sbjct: 3956 -ATQ---LNHAGRYTCVARNAAGSAH-RHVTLHVHE-PPVIQPQPSELHVILNNPILLPC 4009

Query: 130  LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
                G+P P + W+K G  +   G +   L  GG L I  A + DAG Y C+A+N AGT 
Sbjct: 4010 -EATGTPSPFITWQKEGINVNTSGRNHAVLPSGG-LQISRAVREDAGTYMCVAQNPAGTA 4067

Query: 190  ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249
               I  L + + P +    ++ V      +T  C   G P PD+ W +  G   +   R 
Sbjct: 4068 LGKIK-LNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKD-GRAIVESIRQ 4125

Query: 250  KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309
            +VL  GSL++  V   D G Y+C A N  G+ S S  LTV+ PP I  +     V   + 
Sbjct: 4126 RVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQ 4185

Query: 310  ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
            A   C A G P P + W  +    ++   +   KY A    +    L + +    DS   
Sbjct: 4186 AILPCVADGIPTPAINWKKD---NVLLANL-LGKYTAEPYGE----LILENVVLEDS-GF 4236

Query: 370  IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
              C A N AG       LTV        P  T  P + +L         C A   P P +
Sbjct: 4237 YTCVANNAAGEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKL 4291

Query: 430  AWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
             W F    +I  H  +V     LV++ + K DSGTY C A +  G     G + V  P
Sbjct: 4292 TWTFNNN-IIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEP 4348



 Score =  186 bits (452), Expect = 4e-45
 Identities = 151/574 (26%), Positives = 247/574 (43%), Gaps = 34/574 (5%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
            +T    P I   P  + +  ++   L C A G P+P I W K G ++  +  R  +   G
Sbjct: 3707 LTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENG 3766

Query: 66   LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
               +++ H    +D G Y C ATN+ GT R R   L V V        P +         
Sbjct: 3767 FLHIQSAH---VTDTGRYLCMATNAAGTDR-RRIDLQVHV-PPSIAPGPTNMTVIVNVQT 3821

Query: 126  VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH-LVDGGNLVIQDARQTDAGRYQCIARN 184
             L C    G P+P++ W+KNG  L  D +   + L+  G+LVI      D   Y+C   N
Sbjct: 3822 TLAC-EATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTN 3880

Query: 185  AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
             AG  +  +  L + + P +   P D +    +     C   G P P + W ++ G   +
Sbjct: 3881 GAGDDKRTV-DLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKN-GIRLL 3938

Query: 245  PLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
            P G   ++L  G++ +    L   G Y+C A N+ G+      L V++PP I   P+ ++
Sbjct: 3939 PRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELH 3998

Query: 304  VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
            V   N     C ATG P P + W  EG         +  + HA     G   L I+   +
Sbjct: 3999 VILNNPILLPCEATGTPSPFITWQKEGINV-----NTSGRNHAVLPSGG---LQISRAVR 4050

Query: 364  NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
             D+  T +C A N AG++  + KL V     + PP+I+       + +       C A  
Sbjct: 4051 EDA-GTYMCVAQNPAGTALGKIKLNV-----QVPPVISPHLKEYVIAVDKPITLSCEADG 4104

Query: 424  TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
             P P I W+ +G A++++ R+ V + G+L +  +   D+G YTC+A++  G    S  L 
Sbjct: 4105 LPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLT 4164

Query: 484  VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVT--LSWSQNNKIGSSSILGYQVE 541
            V  P  P I   R+ +        ++ I   V D   T  ++W ++N + ++ +  Y  E
Sbjct: 4165 VHVP--PRI---RSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAE 4219

Query: 542  VFSRETLSGNNTPRNSRGWVVIARRV--HQTHYV 573
             +  E +  N    +S  +  +A       TH V
Sbjct: 4220 PYG-ELILENVVLEDSGFYTCVANNAAGEDTHTV 4252



 Score =  182 bits (442), Expect = 7e-44
 Identities = 137/480 (28%), Positives = 205/480 (42%), Gaps = 35/480 (7%)

Query: 9    GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-----SDTHRSILPA 63
            G  P  I++P DV++      TL C   G P P I+W +   + +     S +  S L  
Sbjct: 790  GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRT 849

Query: 64   GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
            G LF L        SD G Y CEA N +G  +S        ++     + P      +G 
Sbjct: 850  GALFILNLW----ASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQ 905

Query: 124  TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
             + L C    G+P P   W KN   LL   +  + +   G+L I+  +  D G Y C+A 
Sbjct: 906  QLTLPCTLLAGNPIPERRWIKNSAMLL--QNPYITVRSDGSLHIERVQLQDGGEYTCVAS 963

Query: 184  NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
            N AGT     + + +H+ P +  G + +    G  VT  C+  G+P P V+W +     +
Sbjct: 964  NVAGTNNKTTSVV-VHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIS 1022

Query: 244  MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-----NLS 298
                +     DGSL + +    + GEY C A N+ G       LTVY  P +      LS
Sbjct: 1023 TSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLS 1082

Query: 299  ---PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
               P  ++V +G      C     P P + W+ E    +I P   R  +  +        
Sbjct: 1083 QDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKE--TQLISPFSPRHTFLPSG------S 1134

Query: 356  LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
            + I +T  +DS    +C A N AG+     KL V       PP I  GP +  + +    
Sbjct: 1135 MKITETRTSDS-GMYLCVATNIAGNVTQAVKLNV-----HVPPKIQRGPKHLKVQVGQRV 1188

Query: 416  VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN-DGTLVLKDLDKSDSGTYTCVASSRHG 474
              PC A  TP P+I W   G  ++ +   +V+N DGTL +     SD+G YTCVA++  G
Sbjct: 1189 DIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAG 1248



 Score =  177 bits (431), Expect = 2e-42
 Identities = 141/487 (28%), Positives = 213/487 (43%), Gaps = 36/487 (7%)

Query: 10   EAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
            + P +I   L +  +A  +P TL+C A G P P I W+K G  +V    + +L +G L  
Sbjct: 4076 QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQI 4135

Query: 69   LRATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
                 G    DAG Y C A N  G++  S   T+HV       R         +    +L
Sbjct: 4136 AFVQPG----DAGHYTCMAANVAGSSSTSTKLTVHVP---PRIRSTEGHYTVNENSQAIL 4188

Query: 128  ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
             C+   G P P + WKK+   LL +   +      G L++++    D+G Y C+A NAAG
Sbjct: 4189 PCVAD-GIPTPAINWKKDN-VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAG 4246

Query: 188  TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
              ++   +L +H+ P     P DV    G  +   C+  G PLP + W  +     +P  
Sbjct: 4247 -EDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTW--TFNNNIIPAH 4303

Query: 248  RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES- 306
               V     L ++ V   D G Y C AENSVG V A G++ V +PP       S  +E  
Sbjct: 4304 FDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPL 4363

Query: 307  GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
            G  A   C   G P PT+ W+ +G    I   + +    + A++      T+N+ D  D 
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYG-----TVNE-DAGD- 4416

Query: 367  RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
                 C A N AG       LT+ S     PPIIT  P    +      +  C A   P+
Sbjct: 4417 ---YTCVATNEAGVVERSMSLTLQS-----PPIITLEPVETVINAGGKIILNCQATGEPQ 4468

Query: 427  PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
            P I W  +G ++  + R NV ++ +L + D  K D+  + CVA +        G++LV  
Sbjct: 4469 PTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARN------LMGSVLVRV 4522

Query: 487  PINPNIH 493
            P+   +H
Sbjct: 4523 PVIVQVH 4529



 Score =  167 bits (406), Expect = 2e-39
 Identities = 149/489 (30%), Positives = 207/489 (42%), Gaps = 36/489 (7%)

Query: 16   EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-DTHRSILPAGGLFFLRATHG 74
            E P DV+V   +   L C A G P+P I+W K G  + S +T R  + A G       +G
Sbjct: 3251 EIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTL--NIYG 3308

Query: 75   RVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
             + SD G Y C ATN  G   R  N  ++V       + E E   +    ++ +EC    
Sbjct: 3309 ALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIEC-RAT 3367

Query: 134  GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
            G+P P + W KNG  L      R+ L  G  + I  A+ +D   Y C+A N AG  ++  
Sbjct: 3368 GTPPPQINWLKNGLPLPLSSHIRL-LAAGQVIRIVRAQVSDVAVYTCVASNRAGV-DNKH 3425

Query: 194  ATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---R 248
              L++   P +    G E++    GSS +  C   G P P + W R       PLG    
Sbjct: 3426 YNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRD----GQPLGLDAH 3481

Query: 249  VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVNVE 305
            + V   G  L+L      D G+Y+C A N  G VS    L V +PP IN S     ++V 
Sbjct: 3482 LTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVI 3541

Query: 306  SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
              N    TC A+G P P M W  +G      P    D+        G  VL I+     D
Sbjct: 3542 VNNPLELTCIASGIPAPKMTWMKDGR-----PLPQTDQ---VQTLGGGEVLRISTAQVED 3593

Query: 366  SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIKSMAVFPCTAICT 424
            +     C A + AG       + V      PP I  T+ P + T+         C +   
Sbjct: 3594 T-GRYTCLASSPAGDDDKEYLVRV----HVPPNIAGTDEPRDITVLRNRQVTLECKSDAV 3648

Query: 425  PEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
            P P+I W   GE L    R  + + G  L + + D  D+  YTCVAS+  GK      L 
Sbjct: 3649 PPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILT 3708

Query: 484  VDSPINPNI 492
            V+ P  PNI
Sbjct: 3709 VNVP--PNI 3715



 Score =  165 bits (402), Expect = 5e-39
 Identities = 132/475 (27%), Positives = 213/475 (44%), Gaps = 39/475 (8%)

Query: 16   EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGLFFLRATHG 74
            EQ  +V+V  +Q   L C   G+PSP I WYK  V V  S T +++     L   RAT  
Sbjct: 1365 EQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATP- 1423

Query: 75   RVHSDAGVYWCEATNSYGTARSR---NATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
                DAG Y C+A N  GT++     +  +   ++   F   P          V LEC  
Sbjct: 1424 ---EDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNF---PNEVSVVLNRDVALEC-Q 1476

Query: 132  PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRE 190
             +G+P P+++W K+G+ L F GD  + L+D G ++ +++AR+ D GRYQC   NAAG + 
Sbjct: 1477 VKGTPFPDIHWFKDGKPL-FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQA 1535

Query: 191  SAIATLKIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
              I  L I+I P +  G    D+     S +  +C   G P+P + W +  G   M   +
Sbjct: 1536 KDI-KLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKD-GQPIMSSSQ 1593

Query: 249  VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NL-SPNSVNV 304
               +D G  L +    ++D   Y+C   N  G    S ++ VY PP I  NL +P +  V
Sbjct: 1594 ALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQV 1653

Query: 305  ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
               +     C A G P P + W  +G      P  + D     A    + +++  + D  
Sbjct: 1654 VIAHSLTLECKAAGNPSPILTWLKDG-----VPVKANDNIRIEAGGKKLEIMSAQEID-- 1706

Query: 365  DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ--TLPIKSMAVFPCTAI 422
              R   +C A + AG   ++ ++ V       PP I  G       + + ++    C   
Sbjct: 1707 --RGQYICVATSVAGEKEIKYEVDVL-----VPPAIEGGDETSYFIVMVNNLLELDCHVT 1759

Query: 423  CTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKY 476
             +P P I W  +G+ + +     +  +G  LV+     S++G Y C+A++  G +
Sbjct: 1760 GSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDH 1814



 Score =  165 bits (402), Expect = 5e-39
 Identities = 131/460 (28%), Positives = 211/460 (45%), Gaps = 31/460 (6%)

Query: 19   LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS 78
            L+ TV    P  L C+A G+P P I WYK   L+   T  + L  G +  + +      S
Sbjct: 1928 LNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQ---IS 1984

Query: 79   DAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
            DAG+Y C A NS G T    +  +HVA                  + V LEC   RG P 
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVHVA---PSISGSNNMVAVVVNNPVRLEC-EARGIPA 2040

Query: 138  PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
            P++ W K+G  +    +    L  G  L +  A+ +D GRY C+A NAAG ++  I  L+
Sbjct: 2041 PSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDI-DLR 2099

Query: 198  IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS- 256
            +++ P ++   ++V      +V   C+    P P + W +  G   +    + + ++ S 
Sbjct: 2100 VYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKD-GHPLLKKPGLSISENRSV 2158

Query: 257  LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVNVESGNVARFTC 314
            L++++  + D G Y+CEA N  G    +  + ++ PP+I  S     + V  GN+    C
Sbjct: 2159 LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLC 2218

Query: 315  TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
             ++G P P + W  +G+  ++   M R       +  G   L I+  +K+D+     C A
Sbjct: 2219 ESSGIPPPNLIWKKKGS-PVLTDSMGR-----VRILSGGRQLQISIAEKSDAA-LYSCVA 2271

Query: 375  VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI----KSMAVFPCTAICTPEPIIA 430
             N AG++     L V        P ITN  S+ T  I    KS+++  C     P P + 
Sbjct: 2272 SNVAGTAKKEYNLQVYI-----RPTITNSGSHPTEIIVTRGKSISL-ECEVQGIPPPTVT 2325

Query: 431  WYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVA 469
            W  +G  LI+     + ++G  L LK++  SD+G Y CVA
Sbjct: 2326 WMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVA 2365



 Score =  161 bits (391), Expect = 1e-37
 Identities = 142/483 (29%), Positives = 205/483 (42%), Gaps = 42/483 (8%)

Query: 5    YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
            ++T  E P +   P + +       ++ C A G P P I W    + +V  +HR  + + 
Sbjct: 605  FLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVG-SHRYRMTSD 663

Query: 65   GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
            G  F++        DAG+Y C A+NS GT + +N+TL   +   +  +       A GD 
Sbjct: 664  GTLFIK---NAAPKDAGIYGCLASNSAGTDK-QNSTLRY-IEAPKLMVVQSELLVALGDI 718

Query: 125  VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIA 182
             V+EC    G P P V W K    L     S   ++D   G L IQ+ +  DAG Y C+A
Sbjct: 719  TVMEC-KTSGIPPPQVKWFKGDLEL---RPSTFLIIDPLLGLLKIQETQDLDAGDYTCVA 774

Query: 183  RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
             N AG R +   TL +   P  I  P DV  + GS+VT  C V G P P + WRR     
Sbjct: 775  INEAG-RATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRL---D 830

Query: 243  NMPL-------GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PP 293
            NMP+         +  L  G+L + N+  +D+G Y CEAEN  G + +   +TV     P
Sbjct: 831  NMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAP 890

Query: 294  SINLSPNSVNVESGNVARFTCT-ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
             I +SP+  NV  G      CT   G P P   W       I    M     + T   DG
Sbjct: 891  LIGISPSVANVIEGQQLTLPCTLLAGNPIPERRW-------IKNSAMLLQNPYITVRSDG 943

Query: 353  VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
               L I      D      C A N AG++     + V        P I +G    +    
Sbjct: 944  --SLHIERVQLQDG-GEYTCVASNVAGTNNKTTSVVV-----HVLPTIQHGQQILSTIEG 995

Query: 413  SMAVFPCTAICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKDLDKSDSGTYTCVASS 471
                 PC A   P+P + W  +GE +  +  + +   DG+L +      +SG Y C A++
Sbjct: 996  IPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 1055

Query: 472  RHG 474
              G
Sbjct: 1056 TAG 1058



 Score =  160 bits (389), Expect = 2e-37
 Identities = 135/481 (28%), Positives = 205/481 (42%), Gaps = 49/481 (10%)

Query: 18   PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
            P ++ V R +  +L C   G P P + W K G  ++      IL  G +  L+  H    
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIH---V 2355

Query: 78   SDAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
            SD G Y C A N  G T +  + ++H           PE+    + ++V L C    G P
Sbjct: 2356 SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTC-EASGIP 2414

Query: 137  EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
             P++ W K+G  +      R+ L  G  L +      DAG+Y C+ RNAAG  E  I  L
Sbjct: 2415 LPSITWFKDGWPVSLSNSVRI-LSGGRMLRLMQTTMEDAGQYTCVVRNAAG-EERKIFGL 2472

Query: 197  KIHIKPYLI--TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254
             + + P+++     EDV  +   SVT  C V G+P+P++ W +             +   
Sbjct: 2473 SVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGG 2532

Query: 255  GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-----NLSPNSVNVESGNV 309
              L++ NV +   G Y+C A +  G  S S  L V+  P+I     + +P  V V   + 
Sbjct: 2533 RFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSP 2592

Query: 310  ARFTCTATGRPEPTMFW-----SVEGNRTI-IFPGMSRDKYHATAVFDGVTVLTINDTDK 363
                C A   P  T+ W      +E NR I I PG             G T+  +N  + 
Sbjct: 2593 TSLVCEAYSYPPATITWFKDGTPLESNRNIRILPG-------------GRTLQILNAQED 2639

Query: 364  NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--------PSNQTLPIKSMA 415
            N  R +  C A N AG      ++ V       PPII  G        P    + + +  
Sbjct: 2640 NAGRYS--CVATNEAGEMIKHYEVKVYI-----PPIINKGDLWGPGLSPKEVKIKVNNTL 2692

Query: 416  VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
               C A   P   ++WY +G+ L  +   N+  +G TL +K+   SD+G YTCVAS+  G
Sbjct: 2693 TLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAG 2752

Query: 475  K 475
            +
Sbjct: 2753 E 2753



 Score =  156 bits (379), Expect = 3e-36
 Identities = 132/470 (28%), Positives = 209/470 (44%), Gaps = 33/470 (7%)

Query: 18   PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
            P +VTV  ++ A + C + GSP+P   W K G  ++ D H   L  G +  +  T     
Sbjct: 2879 PEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQ---I 2935

Query: 78   SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
            +D G Y C A N+ G+A+ +   L+V V       + E+      + + L C    G P 
Sbjct: 2936 TDIGRYVCVAENTAGSAK-KYFNLNVHVPPSVIGPKSENLTVVVNNFISLTC-EVSGFPP 2993

Query: 138  PNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
            P++ W KN Q +  + ++   +V GG  L I  A+ +D G Y CIA N AG  +    +L
Sbjct: 2994 PDLSWLKNEQPIKLNTNTL--IVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKF-SL 3050

Query: 197  KIHIKPYLITGPED----VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL 252
             +++ P +     +    V  + G+SV+ +C     P P + W ++ G        V++L
Sbjct: 3051 TVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKN-GRMITESTHVEIL 3109

Query: 253  DDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES-GNVA 310
             DG  L +    ++D G+Y C A N  G    + +L VY PPSI      V VE+  N  
Sbjct: 3110 ADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPV 3169

Query: 311  RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
              TC ATG P PT+ W     R      +         +  G + L I  +  +DS N  
Sbjct: 3170 TLTCDATGIPPPTIAWLKNHKR------IENSDSLEVRILSGGSKLQIARSQHSDSGN-Y 3222

Query: 371  VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--PSNQTLPIKSMAVFPCTAICTPEPI 428
             C A N  G +     L++     + PP +     PS+ ++ +       C A   P P+
Sbjct: 3223 TCIASNMEGKAQKYYFLSI-----QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3277

Query: 429  IAWYFEGEALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
            I W  +G+ +       +    N  TL +     SD+G YTCVA++  G+
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score =  155 bits (377), Expect = 5e-36
 Identities = 133/483 (27%), Positives = 202/483 (41%), Gaps = 35/483 (7%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRA-GGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
            VT   AP I   P    V   Q  TL C    G+P P  RW K   +++ + + ++   G
Sbjct: 884  VTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG 943

Query: 65   GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
             L   R        D G Y C A+N  GT  ++  ++ V VL    +   +   + +G  
Sbjct: 944  SLHIERVQL----QDGGEYTCVASNVAGT-NNKTTSVVVHVL-PTIQHGQQILSTIEGIP 997

Query: 125  VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
            V L C    G+P+P+V W K G+ L+    ++      G+L +      ++G Y C A N
Sbjct: 998  VTLPC-KASGNPKPSVIWSKKGE-LISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 1055

Query: 185  AAGTRESAIATLKIHIKPYLITG--------PEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
             AG  +  +  L ++++P +           P ++    G  VT  C V   P P + W 
Sbjct: 1056 TAGYAKRKVQ-LTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWA 1114

Query: 237  RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
            +     +    R   L  GS+++     +D G Y C A N  G V+ +  L V+ PP I 
Sbjct: 1115 KETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQ 1174

Query: 297  LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
              P  + V+ G      C A G P P + WS  G+  ++      D  H  +  DG   L
Sbjct: 1175 RGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLV------DGEHHVSNPDG--TL 1226

Query: 357  TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD---DDRPPPIITNGPSNQTLPIKS 413
            +I+    +D+     C A N AG+      L V      +D  PP  T   + Q      
Sbjct: 1227 SIDQATPSDA-GIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNT---TFQERVANQ 1282

Query: 414  MAVFPCTAICTPEPIIAWYFEGEALI-QNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASS 471
               FPC A  TP+P I W   G  L  +    ++  DGT LV+  +   D+G Y CVA +
Sbjct: 1283 RIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVN 1342

Query: 472  RHG 474
              G
Sbjct: 1343 EAG 1345



 Score =  155 bits (377), Expect = 5e-36
 Identities = 138/469 (29%), Positives = 195/469 (41%), Gaps = 34/469 (7%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLFFLR 70
            P I   P  + V   Q   + C A G+P P I W KGG  ++V   H    P G L   +
Sbjct: 1171 PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQ 1230

Query: 71   ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ----GDTVV 126
            AT     SDAG+Y C ATN  GT  +   TLHV        LEP    + Q       + 
Sbjct: 1231 ATP----SDAGIYTCVATNIAGTDETE-ITLHVQEPPTVEDLEPPYNTTFQERVANQRIE 1285

Query: 127  LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
              C P +G+P+P + W  NG+ L         L DG  LVI      D G Y C+A N A
Sbjct: 1286 FPC-PAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEA 1344

Query: 187  GTRESAIATLKIHIKPYLITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
            GT E     LK+H+ P +    +  +V           C V G P P ++W +       
Sbjct: 1345 GTTERKY-NLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKD-NVQVT 1402

Query: 245  PLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNS 301
                ++ +++G  L+L      D G YSC+A N  G       + V  PP+I     PN 
Sbjct: 1403 ESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNE 1462

Query: 302  VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
            V+V         C   G P P + W  +G    +F G          + D   VL + + 
Sbjct: 1463 VSVVLNRDVALECQVKGTPFPDIHWFKDGKP--LFLGDPN-----VELLDRGQVLHLKNA 1515

Query: 362  DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--PSNQTLPIKSMAVFPC 419
             +ND +    C+  N AG      KLT+       PP I  G   ++ ++ I S+    C
Sbjct: 1516 RRND-KGRYQCTVSNAAGKQAKDIKLTIYI-----PPSIKGGNVTTDISVLINSLIKLEC 1569

Query: 420  TAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTC 467
                 P P I WY +G+ ++ + +    + G  L +     SDS TYTC
Sbjct: 1570 ETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTC 1618



 Score =  154 bits (373), Expect = 2e-35
 Identities = 130/464 (28%), Positives = 214/464 (46%), Gaps = 37/464 (7%)

Query: 23   VARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAG 81
            V +++P  L C A G P+P+I W K    V  +  +  I  +G +  +  T   +  DAG
Sbjct: 1838 VVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKT---LLEDAG 1894

Query: 82   VYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ----GDTVVLECLPPRGSPE 137
             Y C ATN+ G  + ++  LHV    E   LE   K   +     + V LEC    G+P 
Sbjct: 1895 RYTCVATNAAGETQ-QHIQLHV---HEPPSLEDAGKMLNETVLVSNPVQLEC-KAAGNPV 1949

Query: 138  PNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATL 196
            P + W K+ +  L  G + M  ++ G ++ I+ A+ +DAG Y+C+A N+AG  E    +L
Sbjct: 1950 PVITWYKDNR--LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATE-LFYSL 2006

Query: 197  KIHIKPYLITGPEDVVA-QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
            ++H+ P  I+G  ++VA    + V  +C   G P P + W +     +     ++VL  G
Sbjct: 2007 QVHVAP-SISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGG 2065

Query: 256  S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
              L L +  ++D G Y+C A N+ G       L VY PP+I     +V+V         C
Sbjct: 2066 RILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLC 2125

Query: 315  TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
             +   P PT+ W  +G+  +  PG+S        + +  +VL I D    D+     C A
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLS--------ISENRSVLKIEDAQVQDT-GRYTCEA 2176

Query: 375  VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK-SMAVFPCTAICTPEPIIAWYF 433
             N AG +     + +      PP I  +    Q   I+ ++    C +   P P + W  
Sbjct: 2177 TNVAGKTEKNYNVNIWV----PPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKK 2232

Query: 434  EGEALIQNH--RRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
            +G  ++ +   R  + + G  L +   +KSD+  Y+CVAS+  G
Sbjct: 2233 KGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAG 2276



 Score =  152 bits (369), Expect = 5e-35
 Identities = 131/473 (27%), Positives = 207/473 (43%), Gaps = 31/473 (6%)

Query: 10   EAPYI--IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGL 66
            E P+I   E+  +++V  + P  L C A G P+P + W K G  L  +D  +++   GG 
Sbjct: 3525 EPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL---GGG 3581

Query: 67   FFLRATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
              LR +  +V  D G Y C A++  G   +     +HV         EP      +   V
Sbjct: 3582 EVLRISTAQVE-DTGRYTCLASSPAGDDDKEYLVRVHVPP-NIAGTDEPRDITVLRNRQV 3639

Query: 126  VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARN 184
             LEC      P P + W +NG+ L      R+ ++ GG  L I +A   D   Y C+A N
Sbjct: 3640 TLECKSD-AVPPPVITWLRNGERL--QATPRVRILSGGRYLQINNADLGDTANYTCVASN 3696

Query: 185  AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG--GG 242
             AG + +    L +++ P +  GP+ +V     S   +C   G P P + WR+      G
Sbjct: 3697 IAG-KTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAG 3755

Query: 243  NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
            N    R  +L++G L + +  + D G Y C A N+ G       L V+ PPSI   P ++
Sbjct: 3756 NH--ARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNM 3813

Query: 303  NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
             V         C ATG P+P++ W   G+  ++    +++ Y   +   G  V+    + 
Sbjct: 3814 TVIVNVQTTLACEATGIPKPSINWRKNGH--LLNVDQNQNSYRLLS--SGSLVII---SP 3866

Query: 363  KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
              D   T  C+  N AG       LTV     + PP I + P++  +   + AV  CTA 
Sbjct: 3867 SVDDTATYECTVTNGAGDDKRTVDLTV-----QVPPSIADEPTDFLVTKHAPAVITCTAS 3921

Query: 423  CTPEPIIAWYFEGEALI-QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
              P P I W   G  L+ +     + + G + +     + +G YTCVA +  G
Sbjct: 3922 GVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAG 3974



 Score =  151 bits (366), Expect = 1e-34
 Identities = 138/476 (28%), Positives = 204/476 (42%), Gaps = 32/476 (6%)

Query: 11   APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
            AP I      V V  + P  L C A G P+P++ W K G  V S ++   + +GG   L 
Sbjct: 2011 APSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGR-ILA 2069

Query: 71   ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
             T  ++ SD G Y C A N+ G  + R+  L V V       E ++        V L C 
Sbjct: 2070 LTSAQI-SDTGRYTCVAVNAAG-EKQRDIDLRVYV-PPNIMGEEQNVSVLISQAVELLC- 2125

Query: 131  PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
                 P P + W K+G  LL      +   +   L I+DA+  D GRY C A N AG  E
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLSIS-ENRSVLKIEDAQVQDTGRYTCEATNVAGKTE 2184

Query: 191  SAIATLKIHIKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGG-NMPL 246
                 + I + P  I G +++   T   G+ ++  C   G P P+++W++         +
Sbjct: 2185 KNY-NVNIWVPPN-IGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSM 2242

Query: 247  GRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS---PNSV 302
            GRV++L  G  L++     +D   YSC A N  G       L VY  P+I  S   P  +
Sbjct: 2243 GRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEI 2302

Query: 303  NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
             V  G      C   G P PT+ W  +G+  I        K     + D   +L + +  
Sbjct: 2303 IVTRGKSISLECEVQGIPPPTVTWMKDGHPLI--------KAKGVEILDEGHILQLKNIH 2354

Query: 363  KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN--GPSNQTLPIKSMAVFPCT 420
             +D+    VC AVN AG +  +  L+V +    PP II N   P N ++  K+     C 
Sbjct: 2355 VSDT-GRYVCVAVNVAGMTDKKYDLSVHA----PPSIIGNHRSPENISVVEKNSVSLTCE 2409

Query: 421  AICTPEPIIAWYFEG-EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
            A   P P I W+ +G    + N  R ++    L L      D+G YTCV  +  G+
Sbjct: 2410 ASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGE 2465



 Score =  149 bits (362), Expect = 3e-34
 Identities = 128/454 (28%), Positives = 194/454 (42%), Gaps = 34/454 (7%)

Query: 31   LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
            L+C   GSP P I W K G L+       IL  G    +     +V S+ G+Y C A N+
Sbjct: 1754 LDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVI--AQAQV-SNTGLYRCMAANT 1810

Query: 91   YGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
             G  +     T+HV    +   L    +   +   V L+C+   G P P++ W K+ Q +
Sbjct: 1811 AGDHKKEFEVTVHVPPTIKSSGLS--ERVVVKYKPVALQCIA-NGIPNPSITWLKDDQPV 1867

Query: 150  LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
                 +      G  L I      DAGRY C+A NAAG  +  I  L +H  P L    +
Sbjct: 1868 NTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQ-LHVHEPPSLEDAGK 1926

Query: 210  --DVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGGGNMP-LGRVKVLDDGSLRLDNV 262
              +      + V  +C+  G+P+P + W    R  +G  +M  L R +++D     +++ 
Sbjct: 1927 MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIID-----IESA 1981

Query: 263  ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEP 322
             ++D G Y C A NS GA      L V+  PSI+ S N V V   N  R  C A G P P
Sbjct: 1982 QISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAP 2041

Query: 323  TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
            ++ W  +G+    F        +   V  G  +L +     +D+     C AVN AG   
Sbjct: 2042 SLTWLKDGSPVSSFS-------NGLQVLSGGRILALTSAQISDT-GRYTCVAVNAAGEKQ 2093

Query: 383  VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH 442
                L V       PP I     N ++ I       C +   P P + W  +G  L++  
Sbjct: 2094 RDIDLRV-----YVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKP 2148

Query: 443  RRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGK 475
              +++ N   L ++D    D+G YTC A++  GK
Sbjct: 2149 GLSISENRSVLKIEDAQVQDTGRYTCEATNVAGK 2182



 Score =  149 bits (361), Expect = 5e-34
 Identities = 136/491 (27%), Positives = 206/491 (41%), Gaps = 33/491 (6%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            EAP ++    ++ VA      + C+  G P P ++W+KG + +   T   I P  GL  +
Sbjct: 700  EAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKI 759

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
            + T      DAG Y C A N  G A  +  TL V      F  EP       G  V L C
Sbjct: 760  QETQDL---DAGDYTCVAINEAGRATGK-ITLDVGS-PPVFIQEPADVSMEIGSNVTLPC 814

Query: 130  LPPRGSPEPNVYWKKNGQTLLFDGD---SRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
               +G PEP + W++     +F      S +  +  G L I +   +D G Y C A N  
Sbjct: 815  YV-QGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQF 873

Query: 187  GTRES-AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLW-RRSAGGGN 243
            G  +S    T+   + P +   P       G  +T  C +  G+P+P+  W + SA    
Sbjct: 874  GKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ 933

Query: 244  MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
             P   + V  DGSL ++ V L D GEY+C A N  G  + +  + V+  P+I      ++
Sbjct: 934  NPY--ITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILS 991

Query: 304  VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
               G      C A+G P+P++ WS +G         S  K+ A A  DG   +    +  
Sbjct: 992  TIEGIPVTLPCKASGNPKPSVIWSKKGE----LISTSSAKFSAGA--DGSLYVV---SPG 1042

Query: 364  NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK------SMAVF 417
             +     VC+A N AG +  + +LTV     RP         +Q  P++           
Sbjct: 1043 GEESGEYVCTATNTAGYAKRKVQLTVYV---RPRVFGDQRGLSQDKPVEISVLAGEEVTL 1099

Query: 418  PCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476
            PC     P PII W  E + +   + R      G++ + +   SDSG Y CVA++  G  
Sbjct: 1100 PCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNV 1159

Query: 477  VWSGALLVDSP 487
              +  L V  P
Sbjct: 1160 TQAVKLNVHVP 1170



 Score =  149 bits (361), Expect = 5e-34
 Identities = 121/466 (25%), Positives = 198/466 (42%), Gaps = 24/466 (5%)

Query: 21   VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
            +TV      +L C + G P P + W K G  V++D+   +    G   L+ +     SDA
Sbjct: 2206 LTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAE-KSDA 2264

Query: 81   GVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
             +Y C A+N  GTA+   N  +++          P      +G ++ LEC   +G P P 
Sbjct: 2265 ALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLEC-EVQGIPPPT 2323

Query: 140  VYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
            V W K+G  L+      + ++D G+++ +++   +D GRY C+A N AG  +     L +
Sbjct: 2324 VTWMKDGHPLI--KAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKY-DLSV 2380

Query: 199  HIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
            H  P +I     PE++     +SV+  C   G PLP + W +     ++    V++L  G
Sbjct: 2381 HAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLS-NSVRILSGG 2439

Query: 256  S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNVESGNVARF 312
              LRL    + D G+Y+C   N+ G       L+V  PP I    +   V V+       
Sbjct: 2440 RMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTL 2499

Query: 313  TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
            TC  TG P P + W  +G      P    + +H   +  G   L I +     +     C
Sbjct: 2500 TCEVTGNPVPEITWHKDGQ-----PLQEDEAHH---IISGGRFLQITNVQVPHT-GRYTC 2550

Query: 373  SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
             A + AG       L V              P + T+ + S     C A   P   I W+
Sbjct: 2551 LASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWF 2610

Query: 433  FEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKYV 477
             +G  L  N    +   G TL + +  + ++G Y+CVA++  G+ +
Sbjct: 2611 KDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMI 2656



 Score =  147 bits (355), Expect = 2e-33
 Identities = 138/533 (25%), Positives = 230/533 (43%), Gaps = 34/533 (6%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFF 68
            E P +I+ P +VTV   + A L C    +    + W +    V +++  R    A     
Sbjct: 518  EPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLE 577

Query: 69   LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVL 127
            L++      +DAG Y C  ++  G++    A++ + V    +  + P+++    G  V +
Sbjct: 578  LKSVK---FNDAGEYHCMVSSEGGSSA---ASVFLTVQEPPKVTVMPKNQSFTGGSEVSI 631

Query: 128  ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
             C    G P+P + W  N   ++  G  R  +   G L I++A   DAG Y C+A N+AG
Sbjct: 632  MC-SATGYPKPKIAWTVNDMFIV--GSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAG 688

Query: 188  TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
            T +   +TL+    P L+    +++   G     +C+  G P P V W +  G   +   
Sbjct: 689  T-DKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFK--GDLELRPS 745

Query: 248  RVKVLDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
               ++D   G L++      D G+Y+C A N  G  +    L V  PP     P  V++E
Sbjct: 746  TFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSME 805

Query: 306  SGNVARFTCTATGRPEPTMFWSVEGNRTII---FPGMSRDKYHATAVFDGVTVLTINDTD 362
             G+     C   G PEPT+ W    N  I    F   S  +    A+F    +L +  +D
Sbjct: 806  IGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF----ILNLWASD 861

Query: 363  KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
            K     T +C A N  G   ++ + TVT       P+I   PS   +        PCT +
Sbjct: 862  K----GTYICEAENQFGK--IQSETTVTV-TGLVAPLIGISPSVANVIEGQQLTLPCTLL 914

Query: 423  C-TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
               P P   W      L+QN    V +DG+L ++ +   D G YTCVAS+  G    + +
Sbjct: 915  AGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTS 974

Query: 482  LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSS 534
            ++V   + P I   +   +S++ G P         +   ++ WS+  ++ S+S
Sbjct: 975  VVVH--VLPTIQHGQQI-LSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTS 1024



 Score =  140 bits (339), Expect = 2e-31
 Identities = 126/466 (27%), Positives = 185/466 (39%), Gaps = 31/466 (6%)

Query: 21   VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
            V V      +L C +   P P I WYK G ++   TH  IL  G +  ++       SD 
Sbjct: 3069 VNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAE---VSDT 3125

Query: 81   GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
            G Y C A N  G    +N  L+V V       E E       + V L C    G P P +
Sbjct: 3126 GQYVCRAINVAG-RDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTC-DATGIPPPTI 3183

Query: 141  YWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
             W KN + +       + ++ GG+ L I  ++ +D+G Y CIA N  G +      L I 
Sbjct: 3184 AWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEG-KAQKYYFLSIQ 3242

Query: 200  IKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDGS 256
            + P +     P DV    G +V   C   G P P + W +      +    R++V  +GS
Sbjct: 3243 VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS 3302

Query: 257  -LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV---ARF 312
             L +   + +D G+Y+C A N  G       L VY  P+I  + +        V      
Sbjct: 3303 TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINI 3362

Query: 313  TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
             C ATG P P + W   G   +  P  S  +  A      +    ++D           C
Sbjct: 3363 ECRATGTPPPQINWLKNG---LPLPLSSHIRLLAAGQVIRIVRAQVSDV------AVYTC 3413

Query: 373  SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEPIIA 430
             A N AG       L V +     PP + N    + + +   S     C    TP P +A
Sbjct: 3414 VASNRAGVDNKHYNLQVFA-----PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 3468

Query: 431  WYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
            W  +G+ L +  H    T+   L L   +  DSG YTC+AS+  G+
Sbjct: 3469 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGE 3514



 Score =  128 bits (309), Expect = 9e-28
 Identities = 128/486 (26%), Positives = 195/486 (40%), Gaps = 50/486 (10%)

Query: 18   PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
            P +++V      +L C A G P P+I W+K G  V       IL  G +  L  T     
Sbjct: 2393 PENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQT---TM 2449

Query: 78   SDAGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEPESKQSAQGDTVVLECLPPRG 134
             DAG Y C   N+ G  R +   L V V   +  E  LE    +  Q  T+  E     G
Sbjct: 2450 EDAGQYTCVVRNAAGEER-KIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVT---G 2505

Query: 135  SPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAI 193
            +P P + W K+GQ L    D   H++ GG  L I + +    GRY C+A + AG +  + 
Sbjct: 2506 NPVPEITWHKDGQPL--QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2563

Query: 194  ATLKIHIKPYLIT-----GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
            + L + + P +        PEDV     S  +  C     P   + W +   G  +   R
Sbjct: 2564 S-LNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKD--GTPLESNR 2620

Query: 249  -VKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN--------LS 298
             +++L  G +L++ N    + G YSC A N  G +     + VY PP IN        LS
Sbjct: 2621 NIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLS 2680

Query: 299  PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
            P  V ++  N     C A   P  ++ W  +G      P  S D  H     +G T L I
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQ-----PLKSDD--HVNIAANGHT-LQI 2732

Query: 359  NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP--------PIITNGPSNQTLP 410
             +   +D+     C A N AG   +   + +                    NG +   + 
Sbjct: 2733 KEAQISDT-GRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVII 2791

Query: 411  IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVA 469
               ++++ C     P P + WY +G  L  + +  +   G  L +      D+G YTCVA
Sbjct: 2792 NNPISLY-CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVA 2850

Query: 470  SSRHGK 475
             +  G+
Sbjct: 2851 VNEAGE 2856



 Score =  126 bits (304), Expect = 4e-27
 Identities = 132/495 (26%), Positives = 209/495 (42%), Gaps = 54/495 (10%)

Query: 12   PYII-EQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            P+I+ E  L DV V   Q  TL C   G+P P I W+K G  +  D    I+  G   FL
Sbjct: 2478 PHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGR--FL 2535

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL----EPESKQSAQGDTV 125
            + T+ +V    G Y C A++  G  +SR+ +L+V V      +     PE          
Sbjct: 2536 QITNVQV-PHTGRYTCLASSPAG-HKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPT 2593

Query: 126  VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
             L C      P   + W K+G  L  + + R+ L  G  L I +A++ +AGRY C+A N 
Sbjct: 2594 SLVC-EAYSYPPATITWFKDGTPLESNRNIRI-LPGGRTLQILNAQEDNAGRYSCVATNE 2651

Query: 186  AGTRESAIATLKIHIKPYLITG--------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
            AG        +K++I P +  G        P++V  +  +++T +C     P   + W +
Sbjct: 2652 AGEMIKHY-EVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYK 2710

Query: 238  SAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI- 295
              G        V +  +G +L++    ++D G Y+C A N  G       + +  PPS  
Sbjct: 2711 D-GQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQ 2769

Query: 296  ------NLSPNSVNVES-----GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
                  N+     N E+      N     C     P PT+ W  +G+     P  S DK 
Sbjct: 2770 KLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGH-----PLTSSDK- 2823

Query: 345  HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG- 403
                +  G  VL I      D+     C AVN AG   ++  + V       PPII    
Sbjct: 2824 --VLILPGGRVLQIPRAKVEDA-GRYTCVAVNEAGEDSLQYDVRVL-----VPPIIKGAN 2875

Query: 404  ---PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDLDK 459
               P   T+ +   A+  C +  +P P  +W  +G+ L++ +H + ++N   L + +   
Sbjct: 2876 SDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQI 2935

Query: 460  SDSGTYTCVASSRHG 474
            +D G Y CVA +  G
Sbjct: 2936 TDIGRYVCVAENTAG 2950



 Score =  123 bits (296), Expect = 3e-26
 Identities = 107/421 (25%), Positives = 180/421 (42%), Gaps = 26/421 (6%)

Query: 78  SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
           SD G Y C A +S GT R++     V+      ++ P +     G+  VL CL    + +
Sbjct: 492 SDEGFYECIAVSSAGTGRAQ-TFFDVSEPPPVIQV-PNNVTVTPGERAVLTCL-IISAVD 548

Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
            N+ W++N + +     +R+  +   +L ++  +  DAG Y C+  +  G+  +A   L 
Sbjct: 549 YNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGS-SAASVFLT 607

Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257
           +   P +   P++     GS V+  C   G P P + W  +     +   R ++  DG+L
Sbjct: 608 VQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVN-DMFIVGSHRYRMTSDGTL 666

Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
            + N    D G Y C A NS G    +  L   + P + +  + + V  G++    C  +
Sbjct: 667 FIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTS 726

Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT-VLTINDTDKNDSRNTIVCSAVN 376
           G P P + W         F G    +     + D +  +L I +T   D+     C A+N
Sbjct: 727 GIPPPQVKW---------FKGDLELRPSTFLIIDPLLGLLKIQETQDLDA-GDYTCVAIN 776

Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436
            AG +   GK+T+   D   PP+    P++ ++ I S    PC     PEP I W     
Sbjct: 777 EAGRA--TGKITL---DVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDN 831

Query: 437 ALIQNHRRNVTN-----DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPN 491
             I +   +V++      G L + +L  SD GTY C A ++ GK      + V   + P 
Sbjct: 832 MPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPL 891

Query: 492 I 492
           I
Sbjct: 892 I 892



 Score =  103 bits (246), Expect = 4e-20
 Identities = 88/327 (26%), Positives = 144/327 (44%), Gaps = 20/327 (6%)

Query: 164 NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223
           NL I     +D G Y+CIA ++AGT   A     +   P +I  P +V    G      C
Sbjct: 483 NLDIAKVTLSDEGFYECIAVSSAGTGR-AQTFFDVSEPPPVIQVPNNVTVTPGERAVLTC 541

Query: 224 RVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVS 282
            +      ++ W+R+     +    R++ L + SL L +V   D GEY C   +  G+ +
Sbjct: 542 LIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSA 601

Query: 283 ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRD 342
           AS +LTV +PP + + P + +   G+     C+ATG P+P + W+V  N   I   +   
Sbjct: 602 ASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTV--NDMFI---VGSH 656

Query: 343 KYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN 402
           +Y  T+  DG   L I +    D+     C A N AG+      L      + P  ++  
Sbjct: 657 RYRMTS--DG--TLFIKNAAPKDA-GIYGCLASNSAGTDKQNSTLRYI---EAPKLMVVQ 708

Query: 403 GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND--GTLVLKDLDKS 460
             S   + +  + V  C     P P + W F+G+  ++     + +   G L +++    
Sbjct: 709 --SELLVALGDITVMECKTSGIPPPQVKW-FKGDLELRPSTFLIIDPLLGLLKIQETQDL 765

Query: 461 DSGTYTCVASSRHGKYVWSGALLVDSP 487
           D+G YTCVA +  G+      L V SP
Sbjct: 766 DAGDYTCVAINEAGRATGKITLDVGSP 792



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 24/92 (26%), Positives = 37/92 (40%), Gaps = 4/92 (4%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
            +T    P I  +P++  +       LNC+A G P P I W + G  +  D   ++L    
Sbjct: 4434 LTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNS 4493

Query: 66   LFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
            L+   A       D   + C A N  G+   R
Sbjct: 4494 LYIADAQ----KEDTSEFECVARNLMGSVLVR 4521


>UniRef50_Q4RJ20 Cluster: Chromosome 1 SCAF15039, whole genome shotgun
            sequence; n=4; Eumetazoa|Rep: Chromosome 1 SCAF15039,
            whole genome shotgun sequence - Tetraodon nigroviridis
            (Green puffer)
          Length = 3493

 Score =  204 bits (499), Expect = 9e-51
 Identities = 146/464 (31%), Positives = 208/464 (44%), Gaps = 26/464 (5%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFFLR 70
            P+I ++P ++ V R  P  + C A G P P ++W K GV + ++    SILP+G L    
Sbjct: 1877 PFIADEPTEMVVTRLSPVVMGCSASGVPEPTVQWSKDGVALPNEERGYSILPSGPLEITS 1936

Query: 71   ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
            A      S  G Y C A N+ G+   R+  L V  +      +P +      + V L C 
Sbjct: 1937 AEL----SHTGRYTCTAENAAGSTH-RHVQLTVQEV-PVIASQPSTLDVILKNPVTLPCR 1990

Query: 131  PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
               GSP P + W+K G ++   G S   ++  G+L I     +D+G Y C+A+N AGT  
Sbjct: 1991 AT-GSPRPTISWQKEGMSISTTGGS-FTVLPNGSLRISTTSVSDSGTYMCVAQNPAGTAL 2048

Query: 191  SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250
              I  LK+ + P + +      A T SSVT QC V G P P V W +  G       R +
Sbjct: 2049 GKIK-LKVQVPPVIGSDTRTYRAPTDSSVTLQCHVDGSPPPSVTWNKD-GQPLAESVRRR 2106

Query: 251  VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310
            VL  GSL+L  V   D G Y+C A N  G VS    LTV  PPSI      V V   +  
Sbjct: 2107 VLSSGSLQLAFVQSEDTGRYTCTAANPAGTVSLEMSLTVQVPPSIRGGEKEVAVVENSRV 2166

Query: 311  RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
            +  C A G P+PT+ W  +GN   +F   S      T +  G  ++T     + +     
Sbjct: 2167 QLVCVAEGVPQPTLSWEKDGN---LF---SESSEEPTVLPSGELIIT---RAQAEDAGRY 2217

Query: 371  VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA 430
             C A N  G       L+V +      P+ T    +  L      +  C     P P I 
Sbjct: 2218 TCVATNELGQDRWTATLSVQTH-----PVFTELLGDVALKKGERLLLACGVNGIPTPHIT 2272

Query: 431  WYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
            W F   +++  H  +      LV++ + K DSGTYTCVA +R G
Sbjct: 2273 WVF-NNSILPVHYDHANGHSQLVIERVTKEDSGTYTCVAENRVG 2315



 Score =  198 bits (484), Expect = 6e-49
 Identities = 155/526 (29%), Positives = 232/526 (44%), Gaps = 27/526 (5%)

Query: 11   APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
            AP I E    V+   ++ A L C   G P P + W K G ++  +  R      G   L 
Sbjct: 1692 APSIEEGSQAVSAPVNKSAVLECVVNGVPPPQVTWRKHGAILAGNNPRYRFAEDGS--LH 1749

Query: 71   ATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
             T  +V SD G Y C ATN  G  R R +  ++V     E RL+ +   + Q     L C
Sbjct: 1750 ITSAQV-SDTGRYLCMATNQAGIQRRRVDLQVYVPPSISEGRLDVKVTVNVQ---TALSC 1805

Query: 130  LPPRGSPEPNVYWKKNGQTLLFDGDSRMH-LVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
                G P P V W KNG+ +  D +  M+ L+  G+LV+      D   Y+C+  N AG 
Sbjct: 1806 -EASGIPRPTVTWMKNGRVINTDQNQNMYRLLTSGSLVVIAPTVEDTAVYECVVSNEAGV 1864

Query: 189  RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
              S    L +H+ P++   P ++V    S V   C   G P P V W +           
Sbjct: 1865 A-SRFINLTVHVPPFIADEPTEMVVTRLSPVVMGCSASGVPEPTVQWSKDGVALPNEERG 1923

Query: 249  VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGN 308
              +L  G L + +  L+  G Y+C AEN+ G+      LTV + P I   P++++V   N
Sbjct: 1924 YSILPSGPLEITSAELSHTGRYTCTAENAAGSTHRHVQLTVQEVPVIASQPSTLDVILKN 1983

Query: 309  VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
                 C ATG P PT+ W  EG  +I   G S      T + +G   L I+ T  +DS  
Sbjct: 1984 PVTLPCRATGSPRPTISWQKEG-MSISTTGGS-----FTVLPNGS--LRISTTSVSDS-G 2034

Query: 369  TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428
            T +C A N AG++  + KL V     + PP+I +       P  S     C    +P P 
Sbjct: 2035 TYMCVAQNPAGTALGKIKLKV-----QVPPVIGSDTRTYRAPTDSSVTLQCHVDGSPPPS 2089

Query: 429  IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPI 488
            + W  +G+ L ++ RR V + G+L L  +   D+G YTC A++  G      +L V  P 
Sbjct: 2090 VTWNKDGQPLAESVRRRVLSSGSLQLAFVQSEDTGRYTCTAANPAGTVSLEMSLTVQVP- 2148

Query: 489  NPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSS 534
             P+I      +V+ +     + +         TLSW ++  + S S
Sbjct: 2149 -PSIR-GGEKEVAVVENSRVQLVCVAEGVPQPTLSWEKDGNLFSES 2192



 Score =  178 bits (434), Expect = 7e-43
 Identities = 133/480 (27%), Positives = 203/480 (42%), Gaps = 30/480 (6%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRS---ILPAGGLFF 68
            P I E  LDV V  +    L+C A G P P + W K G ++ +D +++   +L +G L  
Sbjct: 1784 PSISEGRLDVKVTVNVQTALSCEASGIPRPTVTWMKNGRVINTDQNQNMYRLLTSGSLVV 1843

Query: 69   LRATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
            +  T      D  VY C  +N  G A R  N T+HV     +   EP      +   VV+
Sbjct: 1844 IAPTV----EDTAVYECVVSNEAGVASRFINLTVHVPPFIAD---EPTEMVVTRLSPVVM 1896

Query: 128  ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
             C    G PEP V W K+G  L  + +    ++  G L I  A  +  GRY C A NAAG
Sbjct: 1897 GC-SASGVPEPTVQWSKDGVALPNE-ERGYSILPSGPLEITSAELSHTGRYTCTAENAAG 1954

Query: 188  TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
            +    +  L +   P + + P  +     + VT  CR  G P P + W++     +   G
Sbjct: 1955 STHRHVQ-LTVQEVPVIASQPSTLDVILKNPVTLPCRATGSPRPTISWQKEGMSISTTGG 2013

Query: 248  RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESG 307
               VL +GSLR+    ++D G Y C A+N  G       L V  PP I     +    + 
Sbjct: 2014 SFTVLPNGSLRISTTSVSDSGTYMCVAQNPAGTALGKIKLKVQVPPVIGSDTRTYRAPTD 2073

Query: 308  NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
            +     C   G P P++ W+ +G           +      +  G   L    ++ +  R
Sbjct: 2074 SSVTLQCHVDGSPPPSVTWNKDGQPLA-------ESVRRRVLSSGSLQLAFVQSE-DTGR 2125

Query: 368  NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427
             T  C+A N AG+  +   LTV     + PP I  G     +   S     C A   P+P
Sbjct: 2126 YT--CTAANPAGTVSLEMSLTV-----QVPPSIRGGEKEVAVVENSRVQLVCVAEGVPQP 2178

Query: 428  IIAWYFEGEALIQNHRR-NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
             ++W  +G    ++     V   G L++      D+G YTCVA++  G+  W+  L V +
Sbjct: 2179 TLSWEKDGNLFSESSEEPTVLPSGELIITRAQAEDAGRYTCVATNELGQDRWTATLSVQT 2238



 Score =  172 bits (418), Expect = 6e-41
 Identities = 127/446 (28%), Positives = 190/446 (42%), Gaps = 27/446 (6%)

Query: 30   TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
            TL C   GSP P++ W K G  +     R +L +G L            D G Y C A N
Sbjct: 2077 TLQCHVDGSPPPSVTWNKDGQPLAESVRRRVLSSGSLQLAFVQS----EDTGRYTCTAAN 2132

Query: 90   SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
              GT  S   +L V V     R   +     +   V L C+   G P+P + W+K+G  L
Sbjct: 2133 PAGTV-SLEMSLTVQV-PPSIRGGEKEVAVVENSRVQLVCVA-EGVPQPTLSWEKDGN-L 2188

Query: 150  LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
              +      ++  G L+I  A+  DAGRY C+A N  G ++   ATL +   P       
Sbjct: 2189 FSESSEEPTVLPSGELIITRAQAEDAGRYTCVATNELG-QDRWTATLSVQTHPVFTELLG 2247

Query: 210  DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGE 269
            DV  + G  +   C V G P P + W        +P+          L ++ V   D G 
Sbjct: 2248 DVALKKGERLLLACGVNGIPTPHITW--VFNNSILPVHYDHANGHSQLVIERVTKEDSGT 2305

Query: 270  YSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES-GNVARFTCTATGRPEPTMFWSV 328
            Y+C AEN VG + + G++++ +PP I+    S  +E  G  A   C   G P PT+ WS 
Sbjct: 2306 YTCVAENRVGTIKSLGFVSILEPPIIDGDLRSNRIEPLGGNAVLNCEVRGDPPPTIRWSK 2365

Query: 329  EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT 388
             G    I   + +    + A++  V+          +   +  C A N AG+  V   +T
Sbjct: 2366 NGIHITIGDRIRQLNNGSLAIYGTVS----------EDAGSYTCVATNDAGA--VERSVT 2413

Query: 389  VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN 448
            +T    +  P IT  P    +   S  V  C A   P P I W  +G  L+ N R +  +
Sbjct: 2414 LTL---QRAPTITEEPVGTVVDAGSTVVLNCQAEGEPTPTIEWSQQGRPLLGNDRFSSLS 2470

Query: 449  DGTLVLKDLDKSDSGTYTCVASSRHG 474
            +G+L +  + K D+  Y CVA +  G
Sbjct: 2471 NGSLRISSVQKEDTARYECVARNLVG 2496



 Score =  171 bits (416), Expect = 1e-40
 Identities = 143/471 (30%), Positives = 200/471 (42%), Gaps = 28/471 (5%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRS--ILPA 63
            +T  E P I  QP  + V    P TL CRA GSP P I W K G + +S T  S  +LP 
Sbjct: 1962 LTVQEVPVIASQPSTLDVILKNPVTLPCRATGSPRPTISWQKEG-MSISTTGGSFTVLPN 2020

Query: 64   GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
            G    LR +   V SD+G Y C A N  GTA  +   L V V       +  + ++    
Sbjct: 2021 GS---LRISTTSV-SDSGTYMCVAQNPAGTALGK-IKLKVQV-PPVIGSDTRTYRAPTDS 2074

Query: 124  TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
            +V L+C    GSP P+V W K+GQ L      R  ++  G+L +   +  D GRY C A 
Sbjct: 2075 SVTLQC-HVDGSPPPSVTWNKDGQPLA--ESVRRRVLSSGSLQLAFVQSEDTGRYTCTAA 2131

Query: 184  NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
            N AGT  S   +L + + P +  G ++V     S V   C   G P P + W +     +
Sbjct: 2132 NPAGT-VSLEMSLTVQVPPSIRGGEKEVAVVENSRVQLVCVAEGVPQPTLSWEKDGNLFS 2190

Query: 244  MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
                   VL  G L +      D G Y+C A N +G    +  L+V   P        V 
Sbjct: 2191 ESSEEPTVLPSGELIITRAQAEDAGRYTCVATNELGQDRWTATLSVQTHPVFTELLGDVA 2250

Query: 304  VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
            ++ G      C   G P P + W    N +I+         H+  V + VT        K
Sbjct: 2251 LKKGERLLLACGVNGIPTPHITWVF--NNSILPVHYDHANGHSQLVIERVT--------K 2300

Query: 364  NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
             DS  T  C A N  G+    G +++      PP I  +  SN+  P+   AV  C    
Sbjct: 2301 EDS-GTYTCVAENRVGTIKSLGFVSIL----EPPIIDGDLRSNRIEPLGGNAVLNCEVRG 2355

Query: 424  TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
             P P I W   G  +    R    N+G+L +      D+G+YTCVA++  G
Sbjct: 2356 DPPPTIRWSKNGIHITIGDRIRQLNNGSLAIYGTVSEDAGSYTCVATNDAG 2406



 Score =  170 bits (413), Expect = 2e-40
 Identities = 144/481 (29%), Positives = 212/481 (44%), Gaps = 43/481 (8%)

Query: 17   QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV 76
            +P +V V  +   TL C A   PSPA++WYK G ++  D H SI  +G +  ++  H RV
Sbjct: 607  KPKEVKVKVNSSLTLECAAQAFPSPALQWYKDGQILQVDDHMSITASGRM--VQVEHARV 664

Query: 77   HSDAGVYWCEATNSYGTARSR---NATLHVAVLREEFRLEPESKQSAQGDT--VVLE--- 128
             SD G Y C ATN  G        N  +     R        S    +GD   V+L    
Sbjct: 665  -SDTGRYTCVATNIAGEDEKDFDVNVQVPPNFTRAGGAAGSTSSPGVEGDVRDVILNNPI 723

Query: 129  --CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
                     P P + W K+GQ LL  GD  + L  G  L I  A+  DAGRY C+A N A
Sbjct: 724  SLYCETNAVPPPTLTWYKDGQ-LLASGDKVLILPGGRVLQIPRAQAEDAGRYICMAVNEA 782

Query: 187  GTRESAIATLKIHIKPYLITG-----PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
            G  +S    +++ + P +I G     PE+V      +   +C   G+P P V W + +  
Sbjct: 783  G-EDSIHYDVRVLLPP-IIRGTVSDFPEEVTVLVNKTTQLECHADGNPAPRVSWFQDSQP 840

Query: 242  GNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS-INLSP 299
               P GR ++L +G  L++    ++D G Y C A N  G+   S  L V+ PP  I  +P
Sbjct: 841  VR-PDGRHRILSNGRILQVLTAQVSDTGRYVCVAANVAGSAEKSFNLNVHVPPMVIGSNP 899

Query: 300  NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
             SVNV   +    +C ATG P PT+ W  +        G  +   HA  +  G   L I 
Sbjct: 900  ESVNVVVNSFVSLSCEATGLPPPTLTWLND-------RGPVQANTHA-LIMPGGRTLQIM 951

Query: 360  DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA---- 415
                +D      C A+N AG +     LTV       PP I     +  + + ++A    
Sbjct: 952  KAKVSDG-GKYSCVAMNAAGEAHRHIYLTVFI-----PPSIRGSSGDSPVVVNTLAGKAS 1005

Query: 416  VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHG 474
               C     P P I+WY  G  + ++    +  +G ++ +K    SD+G Y C A++  G
Sbjct: 1006 TLECETSAVPAPSISWYKNGRVVTESANLRILKEGQMLEIKTTGVSDTGQYVCKATNIAG 1065

Query: 475  K 475
            +
Sbjct: 1066 Q 1066



 Score =  156 bits (378), Expect = 4e-36
 Identities = 138/475 (29%), Positives = 209/475 (44%), Gaps = 33/475 (6%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P I  + L+ TV    P  L+C++   P P + W K G  +      ++L  G +  LR 
Sbjct: 3   PNIQGEELNATVMLGGPVVLHCQSDAIPPPTLSWRKDGRPLFRKPGLTVLSDGSV--LRV 60

Query: 72  THGRVHSDAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
              +V  D+G Y CEATN  G T ++ N  + VA        EP      +G+ + + C 
Sbjct: 61  DSAQV-QDSGRYSCEATNVAGKTEKNYNLNVWVAPSIRGSE-EPTPLTVIEGNPITMVC- 117

Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTR 189
              G P P++ W+K+G  L      R+ ++ GG  L I  A +TD   Y C A +A+G  
Sbjct: 118 ESSGIPPPSLVWRKDGSEL--KPTQRLRVLSGGRQLQISSAARTDTASYSCTASSASGI- 174

Query: 190 ESAIATLKIHIKP--YLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
            S   +L+++++P   L  G  D VA T G  VT QC   G P P V W +  G      
Sbjct: 175 TSKEYSLQVYVRPSIKLSEGLSDDVAVTKGGDVTLQCAAEGIPRPAVTWLKD-GRPVSGQ 233

Query: 247 GRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS---PNSV 302
            R KVL++G  L++  V ++D G Y+C A N+ G   +   ++V+ PP I      P +V
Sbjct: 234 HRAKVLNEGRLLQIKTVKVSDTGRYTCVAVNAAGQADSRHDVSVHVPPVITGQVDVPENV 293

Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
           +V   N    +C A+G P P + W  +G      P  +    H   V  G   L +    
Sbjct: 294 SVVLKNPVALSCEASGIPLPAISWLKDGQ-----PVRASSSVH---VLSGGRSLRLMHAA 345

Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT-LPIKSMAVFPCTA 421
             D      C   N AG       L +      PP I   G    T +  K      C  
Sbjct: 346 VGDG-GRYTCVVSNMAGEERKNFDLDILV----PPSIEEEGTVVDTKVKEKHNLTLTCEV 400

Query: 422 ICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGK 475
              P P I W  +G+ L+ +    V ++G  L +     +D+G Y+C+AS+  G+
Sbjct: 401 SGNPVPGIKWLKDGQMLVSDRHHQVFSNGRFLQIFGTRVADTGRYSCLASNSAGE 455



 Score =  155 bits (375), Expect = 9e-36
 Identities = 136/462 (29%), Positives = 195/462 (42%), Gaps = 33/462 (7%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
            +V+V  +    L C A G P+P++ W K G   ++D  R +L  G +  LR    ++  D
Sbjct: 1519 EVSVIVNNDLELQCEASGVPAPSLTWLKDG-RPLADGLR-VLQGGEV--LRVASAQLE-D 1573

Query: 80   AGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
             G Y C A +  G   +     +HV       + E +         V LEC      P P
Sbjct: 1574 TGRYSCLANSPAGDDDKEFLVRVHVPP-NIAGKSETQDVSVLLNRPVTLECKSD-AVPPP 1631

Query: 139  NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG--TRESAIATL 196
             + W K+G+ L      R+ L  G  L I  A   D  +Y C A N AG  TR   +A  
Sbjct: 1632 TLTWLKDGRPLQASARVRI-LSRGSYLQINQAELDDRAQYTCEASNIAGQTTRHFNVA-- 1688

Query: 197  KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG--GGNMPLGRVKVLDD 254
             +H+ P +  G + V A    S   +C V G P P V WR+      GN P  R +  +D
Sbjct: 1689 -VHVAPSIEEGSQAVSAPVNKSAVLECVVNGVPPPQVTWRKHGAILAGNNP--RYRFAED 1745

Query: 255  GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
            GSL + +  ++D G Y C A N  G       L VY PPSI+     V V        +C
Sbjct: 1746 GSLHITSAQVSDTGRYLCMATNQAGIQRRRVDLQVYVPPSISEGRLDVKVTVNVQTALSC 1805

Query: 315  TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL-TINDTDKNDSRNTIVCS 373
             A+G P PT+ W   G   +I    +++ Y        V +  T+ DT   +      C 
Sbjct: 1806 EASGIPRPTVTWMKNGR--VINTDQNQNMYRLLTSGSLVVIAPTVEDTAVYE------CV 1857

Query: 374  AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF 433
              N AG +     LTV       PP I + P+   +   S  V  C+A   PEP + W  
Sbjct: 1858 VSNEAGVASRFINLTV-----HVPPFIADEPTEMVVTRLSPVVMGCSASGVPEPTVQWSK 1912

Query: 434  EGEALIQNHR-RNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
            +G AL    R  ++   G L +   + S +G YTC A +  G
Sbjct: 1913 DGVALPNEERGYSILPSGPLEITSAELSHTGRYTCTAENAAG 1954



 Score =  153 bits (370), Expect = 4e-35
 Identities = 132/471 (28%), Positives = 198/471 (42%), Gaps = 34/471 (7%)

Query: 16   EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGLFFLRATH 73
            E P ++ V  ++   L C+A G+P+P I+W K G  V     +   I P G    +   H
Sbjct: 1233 ELPREMGVLLNESIQLVCQASGTPTPTIQWLKDGEAVNHTGSSELRISPDGTTLTVFGAH 1292

Query: 74   GRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP 132
                +D G Y C ATN+ G   R  N  ++   +        E + +    +V LEC+  
Sbjct: 1293 A---TDGGTYACVATNAAGEEDRIFNLNVYAPPVINGDSETVEERTAVLDASVSLECVAT 1349

Query: 133  RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
             GSP P + W +NG  L      R+ L  G  L I  ++ +D+G Y CIA N AG  +S 
Sbjct: 1350 -GSPPPQLNWLRNGLPLPLSSHVRL-LSAGQVLRITRSQVSDSGAYSCIASNRAGV-DSR 1406

Query: 193  IATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250
               L++H+ P L      EDV    G+ V+  C   G P P V W +  G    P   ++
Sbjct: 1407 HYNLQVHVPPGLDGAGSTEDVTVVGGNMVSLLCVADGTPTPTVSWLKE-GSALFPASNLR 1465

Query: 251  VLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVNVESG 307
             L+ + S+++    + + G YSC A+N+ G  S    L V DPP IN S     V+V   
Sbjct: 1466 FLNLNMSMQIPQAHVNNTGRYSCVAKNTAGQASRHFNLKVLDPPRINGSDVVTEVSVIVN 1525

Query: 308  NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
            N     C A+G P P++ W  +G          R       V  G  VL +      D+ 
Sbjct: 1526 NDLELQCEASGVPAPSLTWLKDG----------RPLADGLRVLQGGEVLRVASAQLEDT- 1574

Query: 368  NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTP 425
                C A + AG       + V       PP I      Q + +         C +   P
Sbjct: 1575 GRYSCLANSPAGDDDKEFLVRV-----HVPPNIAGKSETQDVSVLLNRPVTLECKSDAVP 1629

Query: 426  EPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGK 475
             P + W  +G  L  + R  + + G+ L +   +  D   YTC AS+  G+
Sbjct: 1630 PPTLTWLKDGRPLQASARVRILSRGSYLQINQAELDDRAQYTCEASNIAGQ 1680



 Score =  150 bits (363), Expect = 3e-34
 Identities = 118/374 (31%), Positives = 171/374 (45%), Gaps = 28/374 (7%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFFLRATHGRVHS 78
            +V V  +    L C A G P P + W K G L    +   ++LP+G L   RA       
Sbjct: 2157 EVAVVENSRVQLVCVAEGVPQPTLSWEKDGNLFSESSEEPTVLPSGELIITRAQA----E 2212

Query: 79   DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
            DAG Y C ATN  G  R   ATL V      F          +G+ ++L C    G P P
Sbjct: 2213 DAGRYTCVATNELGQDRW-TATLSVQT-HPVFTELLGDVALKKGERLLLAC-GVNGIPTP 2269

Query: 139  NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
            ++ W  N   L    D   H      LVI+   + D+G Y C+A N  GT +S +  + I
Sbjct: 2270 HITWVFNNSILPVHYD---HANGHSQLVIERVTKEDSGTYTCVAENRVGTIKS-LGFVSI 2325

Query: 199  HIKPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDG 255
             ++P +I G    + +   G +    C V GDP P + W  S  G ++ +G R++ L++G
Sbjct: 2326 -LEPPIIDGDLRSNRIEPLGGNAVLNCEVRGDPPPTIRW--SKNGIHITIGDRIRQLNNG 2382

Query: 256  SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315
            SL +   +  D G Y+C A N  GAV  S  LT+   P+I   P    V++G+     C 
Sbjct: 2383 SLAIYGTVSEDAGSYTCVATNDAGAVERSVTLTLQRAPTITEEPVGTVVDAGSTVVLNCQ 2442

Query: 316  ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
            A G P PT+ WS +G      P +  D++  +++ +G   L I+   K D+     C A 
Sbjct: 2443 AEGEPTPTIEWSQQGR-----PLLGNDRF--SSLSNG--SLRISSVQKEDTAR-YECVAR 2492

Query: 376  NYAGSSFVRGKLTV 389
            N  GS   R  LTV
Sbjct: 2493 NLVGSVLARVPLTV 2506



 Score =  141 bits (341), Expect = 1e-31
 Identities = 132/463 (28%), Positives = 199/463 (42%), Gaps = 32/463 (6%)

Query: 78   SDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
            SD+G Y C A+N  G A +S   T+ V        L P        +++ L C    G+P
Sbjct: 1199 SDSGTYTCVASNVEGRAHKSYRLTIRVPPRISGSEL-PREMGVLLNESIQLVC-QASGTP 1256

Query: 137  EPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195
             P + W K+G+ +   G S + +  DG  L +  A  TD G Y C+A NAAG  E  I  
Sbjct: 1257 TPTIQWLKDGEAVNHTGSSELRISPDGTTLTVFGAHATDGGTYACVATNAAG-EEDRIFN 1315

Query: 196  LKIHIKPYLITGPEDVVAQTG---SSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKV 251
            L ++  P +    E V  +T    +SV+ +C   G P P + W R+  G  +PL   V++
Sbjct: 1316 LNVYAPPVINGDSETVEERTAVLDASVSLECVATGSPPPQLNWLRN--GLPLPLSSHVRL 1373

Query: 252  LDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL--SPNSVNVESGN 308
            L  G  LR+    ++D G YSC A N  G  S    L V+ PP ++   S   V V  GN
Sbjct: 1374 LSAGQVLRITRSQVSDSGAYSCIASNRAGVDSRHYNLQVHVPPGLDGAGSTEDVTVVGGN 1433

Query: 309  VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
            +    C A G P PT+ W  EG  + +FP  S  ++    +   +    +N+T +     
Sbjct: 1434 MVSLLCVADGTPTPTVSWLKEG--SALFPA-SNLRFLNLNMSMQIPQAHVNNTGRYS--- 1487

Query: 369  TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIKSMAVFPCTAICTPEP 427
               C A N AG +     L V      PP I  ++  +  ++ + +     C A   P P
Sbjct: 1488 ---CVAKNTAGQASRHFNLKVLD----PPRINGSDVVTEVSVIVNNDLELQCEASGVPAP 1540

Query: 428  IIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
             + W  +G  L     R +     L +      D+G Y+C+A+S  G        LV   
Sbjct: 1541 SLTWLKDGRPLADG-LRVLQGGEVLRVASAQLEDTGRYSCLANSPAGDD--DKEFLVRVH 1597

Query: 488  INPNI-HFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
            + PNI       DVS L   P      +      TL+W ++ +
Sbjct: 1598 VPPNIAGKSETQDVSVLLNRPVTLECKSDAVPPPTLTWLKDGR 1640



 Score =  138 bits (335), Expect = 6e-31
 Identities = 125/437 (28%), Positives = 189/437 (43%), Gaps = 39/437 (8%)

Query: 16  EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75
           E+P  +TV    P T+ C + G P P++ W K G   +  T R  + +GG     ++  R
Sbjct: 100 EEPTPLTVIEGNPITMVCESSGIPPPSLVWRKDG-SELKPTQRLRVLSGGRQLQISSAAR 158

Query: 76  VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE---PESKQSAQGDTVVLECLPP 132
             +D   Y C A+++ G   S+  +L V V R   +L     +     +G  V L+C   
Sbjct: 159 --TDTASYSCTASSASGIT-SKEYSLQVYV-RPSIKLSEGLSDDVAVTKGGDVTLQC-AA 213

Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRES 191
            G P P V W K+G+ +   G  R  +++ G L+ I+  + +D GRY C+A NAAG  +S
Sbjct: 214 EGIPRPAVTWLKDGRPV--SGQHRAKVLNEGRLLQIKTVKVSDTGRYTCVAVNAAGQADS 271

Query: 192 AIATLKIHIKPYLITG----PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
               + +H+ P +ITG    PE+V     + V   C   G PLP + W +  G       
Sbjct: 272 R-HDVSVHVPP-VITGQVDVPENVSVVLKNPVALSCEASGIPLPAISWLKD-GQPVRASS 328

Query: 248 RVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN--V 304
            V VL  G SLRL +  + D G Y+C   N  G    +  L +  PPSI      V+  V
Sbjct: 329 SVHVLSGGRSLRLMHAAVGDGGRYTCVVSNMAGEERKNFDLDILVPPSIEEEGTVVDTKV 388

Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
           +  +    TC  +G P P + W  +G   +       D++H   VF     L I  T   
Sbjct: 389 KEKHNLTLTCEVSGNPVPGIKWLKDGQMLV------SDRHH--QVFSNGRFLQIFGTRVA 440

Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
           D+     C A N AG       L V       P I  +GP      +   A  P + +C 
Sbjct: 441 DT-GRYSCLASNSAGERSRHYNLNVLVS----PTIAGSGPEGSVEEVTVTASSPTSLLCD 495

Query: 425 ----PEPIIAWYFEGEA 437
               P  ++ W  +G +
Sbjct: 496 AQSYPPAVVTWLRDGSS 512



 Score =  134 bits (323), Expect = 2e-29
 Identities = 145/519 (27%), Positives = 212/519 (40%), Gaps = 77/519 (14%)

Query: 18   PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
            P +VTV  ++   L C A G+P+P + W++    V  D    IL  G +  L+    +V 
Sbjct: 807  PEEVTVLVNKTTQLECHADGNPAPRVSWFQDSQPVRPDGRHRILSNGRI--LQVLTAQV- 863

Query: 78   SDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
            SD G Y C A N  G+A +S N  +HV  +       PES        V L C    G P
Sbjct: 864  SDTGRYVCVAANVAGSAEKSFNLNVHVPPM--VIGSNPESVNVVVNSFVSLSC-EATGLP 920

Query: 137  EPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIAT 195
             P + W  +   +    ++   ++ GG  L I  A+ +D G+Y C+A NAAG     I  
Sbjct: 921  PPTLTWLNDRGPV--QANTHALIMPGGRTLQIMKAKVSDGGKYSCVAMNAAGEAHRHIY- 977

Query: 196  LKIHIKPYL--ITGPEDVVAQT--GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
            L + I P +   +G   VV  T  G + T +C     P P + W ++ G        +++
Sbjct: 978  LTVFIPPSIRGSSGDSPVVVNTLAGKASTLECETSAVPAPSISWYKN-GRVVTESANLRI 1036

Query: 252  LDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD------------------- 291
            L +G  L +    ++D G+Y C+A N  G V  + +L VY                    
Sbjct: 1037 LKEGQMLEIKTTGVSDTGQYVCKATNIAGQVDKNFHLNVYGRARLSVFTHESSCICATMP 1096

Query: 292  ------PPSINLSPNSVNVES-GNVARFTCTATGRPEPTMFWSVEGNRT--IIFPGMSR- 341
                  PP I         E+ GN   F C ATG P P + W   G       FP  SR 
Sbjct: 1097 SQFSAVPPRIEGPAEEDIAETLGNPVSFACDATGIPPPALAWLKNGRPIGGAAFPSFSRL 1156

Query: 342  --DKYHATA------------------VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381
              +K    A                  +F G   L I  +  +DS  T  C A N  G +
Sbjct: 1157 EMEKCVPLAFTCPCELFSENSESLEMHIFSGGGKLQIARSQVSDS-GTYTCVASNVEGRA 1215

Query: 382  FVRGKLTVTSDDDRPPPIITNG--PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL- 438
                +LT+     R PP I+    P    + +       C A  TP P I W  +GEA+ 
Sbjct: 1216 HKSYRLTI-----RVPPRISGSELPREMGVLLNESIQLVCQASGTPTPTIQWLKDGEAVN 1270

Query: 439  -IQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGK 475
               +    ++ DG TL +     +D GTY CVA++  G+
Sbjct: 1271 HTGSSELRISPDGTTLTVFGAHATDGGTYACVATNAAGE 1309



 Score =  109 bits (263), Expect = 3e-22
 Identities = 136/525 (25%), Positives = 210/525 (40%), Gaps = 85/525 (16%)

Query: 16   EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75
            + P+ V     + +TL C     P+P+I WYK G +V    +  IL  G +  ++ T   
Sbjct: 992  DSPVVVNTLAGKASTLECETSAVPAPSISWYKNGRVVTESANLRILKEGQMLEIKTTG-- 1049

Query: 76   VHSDAGVYWCEAT------------NSYGTAR----SRNATLHVAVLREEF-----RLE- 113
              SD G Y C+AT            N YG AR    +  ++   A +  +F     R+E 
Sbjct: 1050 -VSDTGQYVCKATNIAGQVDKNFHLNVYGRARLSVFTHESSCICATMPSQFSAVPPRIEG 1108

Query: 114  PESKQSAQ--GDTVVLECLPPRGSPEPNVYWKKNGQTL---LFDGDSRMHL--------- 159
            P  +  A+  G+ V   C    G P P + W KNG+ +    F   SR+ +         
Sbjct: 1109 PAEEDIAETLGNPVSFAC-DATGIPPPALAWLKNGRPIGGAAFPSFSRLEMEKCVPLAFT 1167

Query: 160  ----------------VDGGNLVIQDARQ--TDAGRYQCIARNAAGTRESAIATLKIHIK 201
                            +  G   +Q AR   +D+G Y C+A N  G R      L I + 
Sbjct: 1168 CPCELFSENSESLEMHIFSGGGKLQIARSQVSDSGTYTCVASNVEG-RAHKSYRLTIRVP 1226

Query: 202  PYLITG---PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN-MPLGRVKVLDDG-S 256
            P  I+G   P ++      S+   C+  G P P + W +     N      +++  DG +
Sbjct: 1227 P-RISGSELPREMGVLLNESIQLVCQASGTPTPTIQWLKDGEAVNHTGSSELRISPDGTT 1285

Query: 257  LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV---ARFT 313
            L +      D G Y+C A N+ G       L VY PP IN    +V   +  +       
Sbjct: 1286 LTVFGAHATDGGTYACVATNAAGEEDRIFNLNVYAPPVINGDSETVEERTAVLDASVSLE 1345

Query: 314  CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
            C ATG P P + W   G   +  P  S    H   +  G  VL I  +  +DS     C 
Sbjct: 1346 CVATGSPPPQLNWLRNG---LPLPLSS----HVRLLSAG-QVLRITRSQVSDS-GAYSCI 1396

Query: 374  AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEPIIAW 431
            A N AG       L V       PP +    S + + +   +M    C A  TP P ++W
Sbjct: 1397 ASNRAGVDSRHYNLQV-----HVPPGLDGAGSTEDVTVVGGNMVSLLCVADGTPTPTVSW 1451

Query: 432  YFEGEALI-QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
              EG AL   ++ R +  + ++ +     +++G Y+CVA +  G+
Sbjct: 1452 LKEGSALFPASNLRFLNLNMSMQIPQAHVNNTGRYSCVAKNTAGQ 1496



 Score =  102 bits (244), Expect = 7e-20
 Identities = 85/283 (30%), Positives = 123/283 (43%), Gaps = 25/283 (8%)

Query: 202 PYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR---VKVLDDGS- 256
           P  I G E +     G  V   C+    P P + WR+       PL R   + VL DGS 
Sbjct: 2   PPNIQGEELNATVMLGGPVVLHCQSDAIPPPTLSWRKDG----RPLFRKPGLTVLSDGSV 57

Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS--PNSVNVESGNVARFTC 314
           LR+D+  + D G YSCEA N  G    +  L V+  PSI  S  P  + V  GN     C
Sbjct: 58  LRVDSAQVQDSGRYSCEATNVAGKTEKNYNLNVWVAPSIRGSEEPTPLTVIEGNPITMVC 117

Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
            ++G P P++ W  +G+                 V  G   L I+   + D+  +  C+A
Sbjct: 118 ESSGIPPPSLVWRKDGSEL--------KPTQRLRVLSGGRQLQISSAARTDTA-SYSCTA 168

Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYF 433
            + +G +     L V     RP   ++ G S+     K   V   C A   P P + W  
Sbjct: 169 SSASGITSKEYSLQVYV---RPSIKLSEGLSDDVAVTKGGDVTLQCAAEGIPRPAVTWLK 225

Query: 434 EGEALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHGK 475
           +G  +   HR  V N+G L+ +K +  SD+G YTCVA +  G+
Sbjct: 226 DGRPVSGQHRAKVLNEGRLLQIKTVKVSDTGRYTCVAVNAAGQ 268



 Score = 92.3 bits (219), Expect = 7e-17
 Identities = 90/318 (28%), Positives = 130/318 (40%), Gaps = 29/318 (9%)

Query: 15  IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74
           ++ P +V+V    P  L+C A G P PAI W K G  V + +   +L  G    LR  H 
Sbjct: 287 VDVPENVSVVLKNPVALSCEASGIPLPAISWLKDGQPVRASSSVHVLSGGR--SLRLMHA 344

Query: 75  RVHSDAGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEPESKQSAQGDTVVLECLP 131
            V  D G Y C  +N  G  R +N  L + V   + EE  +     +     T+  E   
Sbjct: 345 AV-GDGGRYTCVVSNMAGEER-KNFDLDILVPPSIEEEGTVVDTKVKEKHNLTLTCEV-- 400

Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
             G+P P + W K+GQ L+ D   ++   +G  L I   R  D GRY C+A N+AG R S
Sbjct: 401 -SGNPVPGIKWLKDGQMLVSDRHHQV-FSNGRFLQIFGTRVADTGRYSCLASNSAGER-S 457

Query: 192 AIATLKIHIKPYLI-TGP----EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
               L + + P +  +GP    E+V     S  +  C     P   V W R  G      
Sbjct: 458 RHYNLNVLVSPTIAGSGPEGSVEEVTVTASSPTSLLCDAQSYPPAVVTWLRD-GSSFESS 516

Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
             V+VL    + L   +   EG  S        A    G++T        L    +N + 
Sbjct: 517 DHVRVLP--GVTLGMTVKMSEGIRSL-------AYGCHGFITPASAGGRTL--QILNAKE 565

Query: 307 GNVARFTCTATGRPEPTM 324
            +  R+TC A      T+
Sbjct: 566 EDAGRYTCVAANEAGETL 583



 Score = 88.6 bits (210), Expect = 9e-16
 Identities = 91/353 (25%), Positives = 146/353 (41%), Gaps = 43/353 (12%)

Query: 162 GGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL----ITG----PEDVVA 213
           G  L I +A++ DAGRY C+A N AG        LK+ + P++    I G    P++V  
Sbjct: 555 GRTLQILNAKEEDAGRYTCVAANEAGETLKHYE-LKVFVPPHINRNDIPGEGLKPKEVKV 613

Query: 214 QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL-RLDNVILADEGEYSC 272
           +  SS+T +C     P P + W +  G        + +   G + ++++  ++D G Y+C
Sbjct: 614 KVNSSLTLECAAQAFPSPALQWYKD-GQILQVDDHMSITASGRMVQVEHARVSDTGRYTC 672

Query: 273 EAENSVGAVSASGYLTVYDPPSINL------SPNSVNVES-------GNVARFTCTATGR 319
            A N  G       + V  PP+         S +S  VE         N     C     
Sbjct: 673 VATNIAGEDEKDFDVNVQVPPNFTRAGGAAGSTSSPGVEGDVRDVILNNPISLYCETNAV 732

Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379
           P PT+ W  +G         S DK     +  G  VL I      D+    +C AVN AG
Sbjct: 733 PPPTLTWYKDGQLLA-----SGDK---VLILPGGRVLQIPRAQAEDA-GRYICMAVNEAG 783

Query: 380 SSFVRGKLTVTSDDDRPPPII----TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG 435
              +   + V       PPII    ++ P   T+ +       C A   P P ++W+ + 
Sbjct: 784 EDSIHYDVRVLL-----PPIIRGTVSDFPEEVTVLVNKTTQLECHADGNPAPRVSWFQDS 838

Query: 436 EALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
           + +  + R  + ++G ++ +     SD+G Y CVA++  G    S  L V  P
Sbjct: 839 QPVRPDGRHRILSNGRILQVLTAQVSDTGRYVCVAANVAGSAEKSFNLNVHVP 891



 Score = 44.0 bits (99), Expect = 0.025
 Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 4/92 (4%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
            +T   AP I E+P+   V       LNC+A G P+P I W + G  ++ +   S L  G 
Sbjct: 2414 LTLQRAPTITEEPVGTVVDAGSTVVLNCQAEGEPTPTIEWSQQGRPLLGNDRFSSLSNGS 2473

Query: 66   LFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
            L            D   Y C A N  G+  +R
Sbjct: 2474 LRISSVQ----KEDTARYECVARNLVGSVLAR 2501


>UniRef50_Q4SL83 Cluster: Chromosome 7 SCAF14557, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 7 SCAF14557, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 949

 Score =  203 bits (496), Expect = 2e-50
 Identities = 117/295 (39%), Positives = 160/295 (54%), Gaps = 13/295 (4%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSD---THRSILPAG 64
           AP I+  P DV V    PA L+CRA GSP  +  W + G    +  +D       +L  G
Sbjct: 8   APRIVHHPSDVVVKPGNPARLSCRAEGSPQVSFEWLRNGQPLQVTKADGPMVQPMVLSEG 67

Query: 65  GLFFLRATHGRVH-SDAGVYWCEATNSYGTARSRNATLHVA-VLREEFRLEPESKQSAQG 122
            LFFL    GR   S  GVY C A N+ GTA SRNA+L +A +++EEF ++P   + A+G
Sbjct: 68  SLFFLSVGEGRGGPSHEGVYACVARNAAGTAVSRNASLRIAGMMKEEFSVQPSDVEVAEG 127

Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMH--LVDGGNLVIQDARQTDAGRYQ 179
           +  VL C PP G P+PNV WKK+G  + + D    +    V  G L++  A + ++G Y 
Sbjct: 128 EVAVLNCGPPTGRPDPNVLWKKDGVPINVTDPHFTVSGSKVLSGKLIVAPAEKKNSGSYV 187

Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
           C+A N  G RES  A L +  KP L+  PE+   + G S  F C+  GDP P V+W R  
Sbjct: 188 CVAANTVGVRESRAARLSVLAKPTLLLKPENASVRLGESAQFYCQAKGDPPPTVVWSREQ 247

Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
             G +P GR  V  D +L++  V + D G Y+C A N VG V+AS  L V +  S
Sbjct: 248 --GPLPNGRYLVNPDQTLQIHYVTVQDAGTYTCTAANDVGVVTASAQLLVQEAAS 300



 Score = 93.5 bits (222), Expect = 3e-17
 Identities = 87/301 (28%), Positives = 131/301 (43%), Gaps = 28/301 (9%)

Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-----GNMPLGRVKVLDD 254
           + P ++  P DVV + G+     CR  G P     W R+         + P+ +  VL +
Sbjct: 7   VAPRIVHHPSDVVVKPGNPARLSCRAEGSPQVSFEWLRNGQPLQVTKADGPMVQPMVLSE 66

Query: 255 GSLRLDNVIL-----ADEGEYSCEAENSVG-AVSASGYLTVYD--PPSINLSPNSVNVES 306
           GSL   +V       + EG Y+C A N+ G AVS +  L +        ++ P+ V V  
Sbjct: 67  GSLFFLSVGEGRGGPSHEGVYACVARNAAGTAVSRNASLRIAGMMKEEFSVQPSDVEVAE 126

Query: 307 GNVARFTC-TATGRPEPTMFWSVEGNR-TIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
           G VA   C   TGRP+P + W  +G    +  P  +      + V  G   L +   +K 
Sbjct: 127 GEVAVLNCGPPTGRPDPNVLWKKDGVPINVTDPHFT---VSGSKVLSGK--LIVAPAEKK 181

Query: 365 DSRNTIVCSAVNYAGSSFVRG-KLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
           +S  + VC A N  G    R  +L+V +      P +   P N ++ +   A F C A  
Sbjct: 182 NS-GSYVCVAANTVGVRESRAARLSVLAK-----PTLLLKPENASVRLGESAQFYCQAKG 235

Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
            P P + W  E +  + N R  V  D TL +  +   D+GTYTC A++  G    S  LL
Sbjct: 236 DPPPTVVWSRE-QGPLPNGRYLVNPDQTLQIHYVTVQDAGTYTCTAANDVGVVTASAQLL 294

Query: 484 V 484
           V
Sbjct: 295 V 295



 Score = 87.8 bits (208), Expect = 2e-15
 Identities = 76/226 (33%), Positives = 104/226 (46%), Gaps = 20/226 (8%)

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLF---DGD--SRMHLVDGGN--LVIQDAR--Q 172
           G+   L C    GSP+ +  W +NGQ L     DG     M L +G    L + + R   
Sbjct: 23  GNPARLSCRA-EGSPQVSFEWLRNGQPLQVTKADGPMVQPMVLSEGSLFFLSVGEGRGGP 81

Query: 173 TDAGRYQCIARNAAGTRESAIATLKIH--IKPYLITGPEDVVAQTGSSVTFQCRVG-GDP 229
           +  G Y C+ARNAAGT  S  A+L+I   +K      P DV    G      C    G P
Sbjct: 82  SHEGVYACVARNAAGTAVSRNASLRIAGMMKEEFSVQPSDVEVAEGEVAVLNCGPPTGRP 141

Query: 230 LPDVLWRRSAGGGNMP-----LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSA 283
            P+VLW++     N+      +   KVL  G L +      + G Y C A N+VG   S 
Sbjct: 142 DPNVLWKKDGVPINVTDPHFTVSGSKVLS-GKLIVAPAEKKNSGSYVCVAANTVGVRESR 200

Query: 284 SGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVE 329
           +  L+V   P++ L P + +V  G  A+F C A G P PT+ WS E
Sbjct: 201 AARLSVLAKPTLLLKPENASVRLGESAQFYCQAKGDPPPTVVWSRE 246



 Score = 62.5 bits (145), Expect = 7e-08
 Identities = 47/179 (26%), Positives = 79/179 (44%), Gaps = 8/179 (4%)

Query: 659 YYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKP 718
           +YL+G  + +R L     ++  K +  +      ++  L++  KYEF + P+     G+ 
Sbjct: 344 HYLDGFEVLYRSLLPAGSDWAAKKV--TMPAFQCQLGPLKRGFKYEFKVRPYGSNLYGRE 401

Query: 719 SNSRVAQTLDDVPDGPPINIEMFILN--TTTVHLKWSPPELQLQNGIITGYNVVVNWLDV 776
           SN++  +  + VP   P  + + + +    T+HL W PP L   NGI+ GY V   W  V
Sbjct: 402 SNTQHLRVPETVPSASPQTVSISVSHEQNNTIHLSWEPPPLDTHNGILQGYQV---WC-V 457

Query: 777 PANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVG 835
            + +      T       L +  L  G  Y + IAA    G+G  S    F I+ +  G
Sbjct: 458 ESEEQQYQNWTVNSSQKKLDIPALKPGKQYWITIAAVNGAGVGVPSDPHGFLINPQKNG 516


>UniRef50_Q92626 Cluster: Peroxidasin homolog; n=49; Eumetazoa|Rep:
           Peroxidasin homolog - Homo sapiens (Human)
          Length = 1496

 Score =  201 bits (491), Expect = 8e-50
 Identities = 122/387 (31%), Positives = 190/387 (49%), Gaps = 23/387 (5%)

Query: 107 REEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV 166
           R     EP+      G+TV   C    G+P+P + W +N   L    DSR++L+D G L+
Sbjct: 262 RPRITSEPQDADVTSGNTVYFTCRA-EGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLM 320

Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATLKIH---IKPYLITGPEDVVAQTGSSVTFQC 223
           IQ+ ++TD G YQC+A+N AG  ++   TL+      +P  +  P++     G SVT +C
Sbjct: 321 IQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLEC 380

Query: 224 RVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA 280
              G P P + W R   G   PL    RV +   G L + NV+  D GEY+C A N++ +
Sbjct: 381 SATGHPPPRISWTR---GDRTPLPVDPRVNITPSGGLYIQNVVQGDSGEYACSATNNIDS 437

Query: 281 VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340
           V A+ ++ V   P   ++P    V  G    F C A G P P + W+  G++      +S
Sbjct: 438 VHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQ------LS 491

Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII 400
            D+ H   V    T L I+    +D +    C AVN  GS  V   LTV     R  P+ 
Sbjct: 492 VDRRH--LVLSSGT-LRISGVALHD-QGQYECQAVNIIGSQKVVAHLTV---QPRVTPVF 544

Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS 460
            + PS+ T+ + +    PC++   PEP I W  +G  + ++ + +++ +G L + D+  +
Sbjct: 545 ASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEGFLTINDVGPA 604

Query: 461 DSGTYTCVASSRHGKYVWSGALLVDSP 487
           D+G Y CVA +  G    S  L V+ P
Sbjct: 605 DAGRYECVARNTIGSASVSMVLSVNVP 631



 Score =  171 bits (417), Expect = 7e-41
 Identities = 119/391 (30%), Positives = 181/391 (46%), Gaps = 26/391 (6%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG--VLVVSDTHRSILPAGGLF 67
           E P I  +P D  V         CRA G+P P I W +    + + +D+  ++L  G L 
Sbjct: 261 ERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLM 320

Query: 68  FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV--AVLREEFRLEPESKQSAQGDTV 125
                     +D G+Y C A N  G  +++  TL    +  R  F ++P++ +   G++V
Sbjct: 321 I----QNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESV 376

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
            LEC    G P P + W +  +T L   D R+++   G L IQ+  Q D+G Y C A N 
Sbjct: 377 TLEC-SATGHPPPRISWTRGDRTPL-PVDPRVNITPSGGLYIQNVVQGDSGEYACSATNN 434

Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
             +   A A + +   P     P+D V   G +V FQC   G+P P + W +  GG  + 
Sbjct: 435 IDS-VHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTK--GGSQLS 491

Query: 246 LGRVK-VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PPSINLSPNSV 302
           + R   VL  G+LR+  V L D+G+Y C+A N +G+     +LTV     P     P+  
Sbjct: 492 VDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDT 551

Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
            VE G   +  C++ G PEP + W+ +G +          K+H +   +G   LTIND  
Sbjct: 552 TVEVGANVQLPCSSQGEPEPAITWNKDGVQV-----TESGKFHISP--EG--FLTINDVG 602

Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
             D+     C A N  GS+ V   L+V   D
Sbjct: 603 PADA-GRYECVARNTIGSASVSMVLSVNVPD 632



 Score =  138 bits (333), Expect = 1e-30
 Identities = 91/291 (31%), Positives = 138/291 (47%), Gaps = 14/291 (4%)

Query: 5   YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPA 63
           Y  S   P  + QP +  V   +  TL C A G P P I W +G    +  D   +I P+
Sbjct: 352 YFGSPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPS 411

Query: 64  GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
           GGL+      G    D+G Y C ATN+  +  +  A + V  L  +F + P+ +   +G 
Sbjct: 412 GGLYIQNVVQG----DSGEYACSATNNIDSVHA-TAFIIVQAL-PQFTVTPQDRVVIEGQ 465

Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIA 182
           TV  +C   +G+P P + W K G  L  D   R HLV   G L I      D G+Y+C A
Sbjct: 466 TVDFQC-EAKGNPPPVIAWTKGGSQLSVD---RRHLVLSSGTLRISGVALHDQGQYECQA 521

Query: 183 RNAAGTRE-SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
            N  G+++  A  T++  + P   + P D   + G++V   C   G+P P + W +  G 
Sbjct: 522 VNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKD-GV 580

Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
                G+  +  +G L +++V  AD G Y C A N++G+ S S  L+V  P
Sbjct: 581 QVTESGKFHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVLSVNVP 631



 Score =  107 bits (258), Expect = 1e-21
 Identities = 82/295 (27%), Positives = 126/295 (42%), Gaps = 19/295 (6%)

Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGSLRL 259
           +P + + P+D    +G++V F CR  G+P P+++W R+    +M    R+ +LDDG+L +
Sbjct: 262 RPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLMI 321

Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVY--DP--PSINLSPNSVNVESGNVARFTCT 315
            N    D+G Y C A+N  G V        Y   P  P+  + P +  V  G      C+
Sbjct: 322 QNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLECS 381

Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
           ATG P P + W+  G+RT + P   R     +    G+ +  +   D  +      CSA 
Sbjct: 382 ATGHPPPRISWT-RGDRTPL-PVDPRVNITPSG---GLYIQNVVQGDSGE----YACSAT 432

Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG 435
           N   S      + V +      P  T  P ++ +       F C A   P P+IAW   G
Sbjct: 433 NNIDSVHATAFIIVQA-----LPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGG 487

Query: 436 EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
             L  + R  V + GTL +  +   D G Y C A +  G       L V   + P
Sbjct: 488 SQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTP 542


>UniRef50_Q4SR23 Cluster: Chromosome 11 SCAF14528, whole genome
           shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 11
           SCAF14528, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 900

 Score =  187 bits (456), Expect = 1e-45
 Identities = 148/510 (29%), Positives = 219/510 (42%), Gaps = 51/510 (10%)

Query: 31  LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
           +NCRA G+P P  RW   G  + +++  +   A G   ++  H  V +  GVY C ATN+
Sbjct: 24  INCRAKGNPPPHYRWTVDGREISTESDPNYSLAEGNLLIKNPH--VVNHRGVYQCIATNT 81

Query: 91  YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
           +GT  SR A +  A L    R         +G  VVL C PP    E    W  NG+   
Sbjct: 82  FGTIVSRQAKVQFAFLENFSRKSRSIVSVREGQAVVLLCGPPLHYGEIKYSWVFNGRRGF 141

Query: 151 FDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG-- 207
              D+R  +    GNL I      DAG Y C  RN         +   + ++   + G  
Sbjct: 142 LQQDARRFISQRTGNLYIAKVEALDAGNYTCAVRNMMTNATVFSSPTPVVVRGDAVMGEY 201

Query: 208 --------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLR 258
                   P+ +    GSSVT +C   G+P+P + WRR A G  +P G++K+    G L 
Sbjct: 202 EPKIEVQFPDTLRVSKGSSVTLECFALGNPVPSISWRR-ADGNPLP-GKIKINHSTGVLE 259

Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL--SPNSVNVESGNVARFTCTA 316
           +      D G Y C AENS G   A G L   +   +    +P   ++  G   ++ C A
Sbjct: 260 IPYFRPEDAGVYECVAENSRGLNVARGQLLFQNVEHLQWVHTPKDADIAIGASLQWECKA 319

Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
            G P P   W   G    I P     + +  A    +T ++++D+          C A N
Sbjct: 320 MGNPRPAYKWLKNGQ---ILP--KEGEIYVEAGKLSITRISLSDSGMYQ------CVAHN 368

Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK--SMAVFPCTAICTPEPIIAWYFE 434
             GS +   +L V +     PP  T  P  ++  ++    AV  C    +P  + +W+  
Sbjct: 369 EHGSVYASAELKVVAS----PPDFTLRPVKKSTVVQRGGEAVLECRPYASPRAVTSWWRG 424

Query: 435 GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHF 494
           GE L    R+ V +DGTL + ++ K D G YTCVA +  G    +G L+V  P       
Sbjct: 425 GELLKDTERQTVMDDGTLRITNISKFDGGRYTCVARNHFGTSSSTGTLVVKGP------- 477

Query: 495 FRAADVSSLPGPPTKPITHNVTDTSVTLSW 524
                    PGPP      +++DT+V LSW
Sbjct: 478 ---------PGPPEALAVTDISDTTVQLSW 498



 Score = 91.9 bits (218), Expect = 1e-16
 Identities = 72/218 (33%), Positives = 103/218 (47%), Gaps = 17/218 (7%)

Query: 15  IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74
           +  P D  +A        C+A G+P PA +W K G ++  +     + AG L   R +  
Sbjct: 299 VHTPKDADIAIGASLQWECKAMGNPRPAYKWLKNGQILPKE-GEIYVEAGKLSITRIS-- 355

Query: 75  RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA--QGDTVVLECLPP 132
              SD+G+Y C A N +G+  + +A L V     +F L P  K +   +G   VLEC  P
Sbjct: 356 --LSDSGMYQCVAHNEHGSVYA-SAELKVVASPPDFTLRPVKKSTVVQRGGEAVLEC-RP 411

Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
             SP     W + G+ LL D + R  ++D G L I +  + D GRY C+ARN  GT  S+
Sbjct: 412 YASPRAVTSWWRGGE-LLKDTE-RQTVMDDGTLRITNISKFDGGRYTCVARNHFGT-SSS 468

Query: 193 IATLKIHIKPYLITGPEDVVAQTG-SSVTFQCRVGGDP 229
             TL +   P    GP + +A T  S  T Q   G  P
Sbjct: 469 TGTLVVKGPP----GPPEALAVTDISDTTVQLSWGSGP 502



 Score = 65.7 bits (153), Expect = 7e-09
 Identities = 45/122 (36%), Positives = 60/122 (49%), Gaps = 5/122 (4%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P  I  P++ T+ R++    +C A GSP P+ RW   G  + S      + +GG   LR 
Sbjct: 738 PGSIVYPVE-TLERNKEVVFSCEAQGSPPPSYRWKLNGTEISSKYGSHYILSGGN--LRI 794

Query: 72  THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLECL 130
                  DAG Y C A+NS+GT  SR A+L  A L E F+    S     +G  VVL C 
Sbjct: 795 NRLNKDQDAGTYQCLASNSFGTIVSREASLTFAYL-ENFKTHRRSSVFVREGQGVVLLCG 853

Query: 131 PP 132
           PP
Sbjct: 854 PP 855



 Score = 51.2 bits (117), Expect = 2e-04
 Identities = 34/101 (33%), Positives = 49/101 (48%), Gaps = 4/101 (3%)

Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA-RQTDAGRYQCIAR 183
           VV  C   +GSP P+  WK NG  +     S  +++ GGNL I    +  DAG YQC+A 
Sbjct: 754 VVFSC-EAQGSPPPSYRWKLNGTEISSKYGSH-YILSGGNLRINRLNKDQDAGTYQCLAS 811

Query: 184 NAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQC 223
           N+ GT  S  A+L   +++ +       V  + G  V   C
Sbjct: 812 NSFGTIVSREASLTFAYLENFKTHRRSSVFVREGQGVVLLC 852



 Score = 44.8 bits (101), Expect = 0.015
 Identities = 48/173 (27%), Positives = 78/173 (45%), Gaps = 13/173 (7%)

Query: 663 GLFIYFRPLDNITIEYEMKTILHSNDVSGF--EITSLRKYTKYEFFLIPFYKKFEGKPSN 720
           G  + FRP  + T    ++T+L S D S +  +  S+   T +E  +  +    EG+ S 
Sbjct: 565 GYIVAFRPAGSSTW---IQTVLASPDASRYIYKDDSIEPLTLFEVKVGVYNSIGEGQFSR 621

Query: 721 SRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANK 780
                + ++ P+ PP NIE  + N + + L W   +       +TGY VV       A  
Sbjct: 622 MVRVFSAEEAPNRPPSNIEWKLTN-SKIFLNWEHVKAMENESEVTGYKVVYR----QAWN 676

Query: 781 SMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRS 833
           SM ++  T    TS+ +  + SG +Y ++I A T  G G  S  +     SRS
Sbjct: 677 SMTSVLET--NKTSMAL-QIPSGENYLIEIKALTEGGDGSSSGPIRIPKMSRS 726



 Score = 42.7 bits (96), Expect = 0.059
 Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 7/87 (8%)

Query: 398 PIITNGPSNQTLPIKSM-----AVFPCTAICTPEPIIAWYFEGEALIQNHRRN-VTNDGT 451
           P+ T  P +   P++++      VF C A  +P P   W   G  +   +  + + + G 
Sbjct: 732 PVFTKQPGSIVYPVETLERNKEVVFSCEAQGSPPPSYRWKLNGTEISSKYGSHYILSGGN 791

Query: 452 LVLKDLDKS-DSGTYTCVASSRHGKYV 477
           L +  L+K  D+GTY C+AS+  G  V
Sbjct: 792 LRINRLNKDQDAGTYQCLASNSFGTIV 818



 Score = 40.3 bits (90), Expect = 0.31
 Identities = 25/95 (26%), Positives = 41/95 (43%), Gaps = 2/95 (2%)

Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
           +R S + +     +P  I  P + + +    V F C   G P P   W+ +    +   G
Sbjct: 724 SRSSILQSPVFTKQPGSIVYPVETL-ERNKEVVFSCEAQGSPPPSYRWKLNGTEISSKYG 782

Query: 248 RVKVLDDGSLRLDNVIL-ADEGEYSCEAENSVGAV 281
              +L  G+LR++ +    D G Y C A NS G +
Sbjct: 783 SHYILSGGNLRINRLNKDQDAGTYQCLASNSFGTI 817


>UniRef50_Q4S2G3 Cluster: Chromosome undetermined SCAF14761, whole
            genome shotgun sequence; n=2; Clupeocephala|Rep:
            Chromosome undetermined SCAF14761, whole genome shotgun
            sequence - Tetraodon nigroviridis (Green puffer)
          Length = 2528

 Score =  186 bits (454), Expect = 2e-45
 Identities = 141/474 (29%), Positives = 211/474 (44%), Gaps = 33/474 (6%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
            +T  E+P I     +V V  H    L C A G P P+I W + GV + +    S+L  G 
Sbjct: 1263 LTVQESPEIGPMAEEVQVVLHHGTVLPCEAQGFPRPSITWQREGVSIATGHRLSVLSNGA 1322

Query: 66   LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNA-TLHVAVLREEFRLEPESKQSAQGDT 124
            L F R T G    DAG+Y C A N  G A  R    L V  +    R+E     S  G  
Sbjct: 1323 LKFSRVTLG----DAGMYQCLAKNEAGVAVGRTRLVLQVPPVLSVPRME---YTSVLGQP 1375

Query: 125  VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
            V LEC+   G P P V W K  + ++ +G + + +   G L I   +++DAG Y C A+N
Sbjct: 1376 VSLECVAD-GQPPPEVAWLKERRPVI-EG-AHIRIFANGTLAIASTQRSDAGLYTCTAKN 1432

Query: 185  AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GN 243
             AG R S    L I + P +     D+    G      C   G P P + W ++     N
Sbjct: 1433 LAG-RASHDMRLAIQVPPLISPAQTDLSVVQGFQALLPCAAQGSPEPRISWEKNGTPVPN 1491

Query: 244  MPLGRVKVLDDGSLRLDN--VILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
            +P G+  VL  G L ++   V  AD G ++C A N+ G+      L++   P+    P  
Sbjct: 1492 LP-GKYTVLRSGELIIERAEVSWADAGVFTCVATNTAGSARQDSRLSINMRPAFKELPGD 1550

Query: 302  VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
            V +  G     +C A G P P + W+V  +      G + D+        G + L I + 
Sbjct: 1551 VTLNKGQNLALSCHAQGTPPPVISWTVNNSPQT---GATLDE-------SGRSSLIIENV 1600

Query: 362  DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN-GPSNQTLPIKSMAVFPCT 420
              + +  T VC A N  GS      + V     R PP++      +QT+   S A+  C 
Sbjct: 1601 TTSHA-GTYVCIAENSVGSIRALSFVRV-----REPPVLKGEARMSQTVVQGSSAILDCP 1654

Query: 421  AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
                P P++ W  +G  L+++HR     +G+LV+  ++ +D G Y C+A S  G
Sbjct: 1655 IHGDPSPVLQWLRDGHPLLRSHRIQALLNGSLVIYSINAADEGEYQCLAESEAG 1708



 Score =  169 bits (412), Expect = 3e-40
 Identities = 142/472 (30%), Positives = 217/472 (45%), Gaps = 40/472 (8%)

Query: 17  QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV 76
           + L+ T+  H   TL+C+A G P P+I W K G  + S         G    L       
Sbjct: 445 ESLNYTLGSH--VTLSCQASGFPVPSITWLKDGTPIESSLQWQWSIRGNRLELGPL---T 499

Query: 77  HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLECLPPRGS 135
            +  GVY C A NS G  + ++  L V V       E  S+ SA  G+ + LEC    G+
Sbjct: 500 LAHGGVYTCVAENSEGQTQ-KDYALTVQVSPTILDSEHPSEVSAPMGEELSLEC-QATGN 557

Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLV---DGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
           P P++ W K+G  ++ +G    H+V   +G  L +      D+G Y C+A + AG R++ 
Sbjct: 558 PTPHLSWLKDG--VIVEGSDNRHIVATPEGSALTLLRLSPDDSGTYTCLAVSPAG-RQTK 614

Query: 193 IATLKIHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249
           I TL + + P +    T P +V     S VT +C+V G P P + W ++ G   +   R 
Sbjct: 615 IYTLFVLVPPSIAGETTVPREVPVTQDSVVTLECQVAGSPPPQISWLKN-GHPLLLSPRT 673

Query: 250 KVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN-LSP-NSVNVES 306
           ++L  D  LR+  V L+D G Y+C A +  G    S  + V  PP ++ + P   V +  
Sbjct: 674 RLLSADSVLRISPVQLSDSGVYTCVARSQAGLAELSYDVQVQVPPGVDHVEPVEPVTIVQ 733

Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV-TVLTINDTDKND 365
           G++   +C A G P PT+ W  +G    +         H   + DG  T L + D   +D
Sbjct: 734 GSLVTLSCEARGVPPPTLTWFKDGQPLSL---------HRNLLLDGQETRLQLPDVATSD 784

Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN-GPSNQTLPIKSMAVFPCTAICT 424
           +     C A N AGSS     LTV      PP + ++  P   T+ + S     C+A   
Sbjct: 785 A-GLYSCVASNQAGSSTKTFNLTVLE----PPKMTSSTSPEELTIAVNSPLELECSATGV 839

Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHGK 475
           P P + W  +G  L  +    V  DG L+ +  +   D+G YTC+ASS  G+
Sbjct: 840 PPPTLTWLKDGHPLELSD--IVQEDGHLIRISKVQVEDAGLYTCLASSLAGE 889



 Score =  161 bits (391), Expect = 1e-37
 Identities = 143/464 (30%), Positives = 198/464 (42%), Gaps = 29/464 (6%)

Query: 20  DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
           +V+V   +  +L C     P P I W + G ++   +   ILP G +  L+    R+  D
Sbjct: 261 EVSVTEGRMVSLLCDVQAYPPPEITWTRDGQVLAFGSGIHILPGGQM--LQLPRARLE-D 317

Query: 80  AGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
           AG Y C ATNS G  + ++  L V V   L+       +      G +V+L C    G P
Sbjct: 318 AGQYVCTATNSAGQDQ-KSILLSVYVRPSLKPRLDAASDLVTPQVGSSVILSC-EAHGVP 375

Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
           EP V W KNG  L       M   D   L I   +  D G Y C   N AG  +     L
Sbjct: 376 EPEVTWYKNGLQLAPRNGFEM---DRYQLEIVGVQVADDGTYTCKVSNVAGQVDRTFR-L 431

Query: 197 KIHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
            +H+ P L     + +  T GS VT  C+  G P+P + W +        L     +   
Sbjct: 432 TVHVPPVLEGSLWESLNYTLGSHVTLSCQASGFPVPSITWLKDGTPIESSLQWQWSIRGN 491

Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS--PNSVNVESGNVARFT 313
            L L  + LA  G Y+C AENS G       LTV   P+I  S  P+ V+   G      
Sbjct: 492 RLELGPLTLAHGGVYTCVAENSEGQTQKDYALTVQVSPTILDSEHPSEVSAPMGEELSLE 551

Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
           C ATG P P + W  +G   +I  G   D  H  A  +G + LT+     +DS  T  C 
Sbjct: 552 CQATGNPTPHLSWLKDG---VIVEGS--DNRHIVATPEG-SALTLLRLSPDDS-GTYTCL 604

Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK--SMAVFPCTAICTPEPIIAW 431
           AV+ AG       L V      PP I       + +P+   S+    C    +P P I+W
Sbjct: 605 AVSPAGRQTKIYTLFVLV----PPSIAGETTVPREVPVTQDSVVTLECQVAGSPPPQISW 660

Query: 432 YFEGEALIQNHR-RNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
              G  L+ + R R ++ D  L +  +  SDSG YTCVA S+ G
Sbjct: 661 LKNGHPLLLSPRTRLLSADSVLRISPVQLSDSGVYTCVARSQAG 704



 Score =  159 bits (386), Expect = 4e-37
 Identities = 147/541 (27%), Positives = 242/541 (44%), Gaps = 46/541 (8%)

Query: 4    DY-VTSGEAPYII--EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI 60
            DY +T   +P I+  E P +V+    +  +L C+A G+P+P + W K GV+V    +R I
Sbjct: 520  DYALTVQVSPTILDSEHPSEVSAPMGEELSLECQATGNPTPHLSWLKDGVIVEGSDNRHI 579

Query: 61   L--PAG-GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEP 114
            +  P G  L  LR +      D+G Y C A +  G  +++  TL V V   +  E  + P
Sbjct: 580  VATPEGSALTLLRLS----PDDSGTYTCLAVSPAG-RQTKIYTLFVLVPPSIAGETTV-P 633

Query: 115  ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTD 174
                  Q   V LEC    GSP P + W KNG  LL    +R+   D   L I   + +D
Sbjct: 634  REVPVTQDSVVTLEC-QVAGSPPPQISWLKNGHPLLLSPRTRLLSAD-SVLRISPVQLSD 691

Query: 175  AGRYQCIARNAAGTRESAIATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
            +G Y C+AR+ AG  E +   +++ + P +  +   E V    GS VT  C   G P P 
Sbjct: 692  SGVYTCVARSQAGLAELSY-DVQVQVPPGVDHVEPVEPVTIVQGSLVTLSCEARGVPPPT 750

Query: 233  VLWRRSAGGGNMPLGRVKVLD--DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290
            + W +   G  + L R  +LD  +  L+L +V  +D G YSC A N  G+ + +  LTV 
Sbjct: 751  LTWFKD--GQPLSLHRNLLLDGQETRLQLPDVATSDAGLYSCVASNQAGSSTKTFNLTVL 808

Query: 291  DPPSI--NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
            +PP +  + SP  + +   +     C+ATG P PT+ W  +G+   +   +  D +    
Sbjct: 809  EPPKMTSSTSPEELTIAVNSPLELECSATGVPPPTLTWLKDGHPLELSDIVQEDGH---- 864

Query: 349  VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQ 407
                  ++ I+     D+     C A + AG       + V      PP +  ++     
Sbjct: 865  ------LIRISKVQVEDA-GLYTCLASSLAGEDGKNHWIRV----QVPPTLFGSDEVKTL 913

Query: 408  TLPIKSMAVFPCTAICTPEPIIAWY-FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYT 466
            T+P+       C A   P P I WY  E +  +    + +     L ++++   DSG Y+
Sbjct: 914  TVPVNGHLTLECLADSDPAPEIEWYKDEVKVQLGGRVQQLAGGQYLEIQEVRPEDSGLYS 973

Query: 467  CVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQ 526
            CV ++  G    S    V+  + P I    +++V++  G     +     D   T++W +
Sbjct: 974  CVVTNMAGSS--SLFFTVEILLPPKIR-ESSSEVTTHVGQDALLLCEVEEDAQATVTWRK 1030

Query: 527  N 527
            +
Sbjct: 1031 D 1031



 Score =  159 bits (385), Expect = 6e-37
 Identities = 132/477 (27%), Positives = 189/477 (39%), Gaps = 24/477 (5%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P I E   +VT    Q A L C         + W K G  +  D   ++L  G L     
Sbjct: 995  PKIRESSSEVTTHVGQDALLLCEVEEDAQATVTWRKDGFPITQDHKYTLLSEGSL----R 1050

Query: 72   THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
             H    SDAG Y+C  +N  G+   R   L V V        P +     G   VL C  
Sbjct: 1051 VHDVQLSDAGRYYCSVSNQAGSDH-RGIYLRVFVA-PAISPGPFNVTVTAGMRAVLSC-E 1107

Query: 132  PRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
              G P P V WK+NG+ L +        L+  G+LV+      D G ++C A N AG  E
Sbjct: 1108 TTGIPPPKVSWKRNGKPLDVSQLSGAFRLLSSGSLVLLSPSDEDEGYFECTAVNDAG-EE 1166

Query: 191  SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250
              +  + + + P +      V A   S V   C V G P P V+W +S    +   G  +
Sbjct: 1167 RRVVEVILQVPPTIEDDVTAVTAVKMSPVALPCHVQGRPQPTVVWTKSGAKLSSRGGTYR 1226

Query: 251  VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310
            VL  G L +  V+ +  G Y+C A NS G       LTV + P I      V V   +  
Sbjct: 1227 VLPTGLLEITAVLPSHAGRYTCSARNSAGLAHKHISLTVQESPEIGPMAEEVQVVLHHGT 1286

Query: 311  RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
               C A G P P++ W  EG        +S    H  +V      L  +     D+    
Sbjct: 1287 VLPCEAQGFPRPSITWQREG--------VSIATGHRLSVLSN-GALKFSRVTLGDA-GMY 1336

Query: 371  VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA 430
             C A N AG +  R +L +     + PP+++      T  +       C A   P P +A
Sbjct: 1337 QCLAKNEAGVAVGRTRLVL-----QVPPVLSVPRMEYTSVLGQPVSLECVADGQPPPEVA 1391

Query: 431  WYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
            W  E   +I+     +  +GTL +    +SD+G YTC A +  G+      L +  P
Sbjct: 1392 WLKERRPVIEGAHIRIFANGTLAIASTQRSDAGLYTCTAKNLAGRASHDMRLAIQVP 1448



 Score =  156 bits (379), Expect = 3e-36
 Identities = 126/468 (26%), Positives = 200/468 (42%), Gaps = 33/468 (7%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS--DTHRSILPAGGLFFL 69
            P I +    VT  +  P  L C   G P P + W K G  + S   T+R +LP G L  +
Sbjct: 1178 PTIEDDVTAVTAVKMSPVALPCHVQGRPQPTVVWTKSGAKLSSRGGTYR-VLPTG-LLEI 1235

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV-LREEFRLEP--ESKQSAQGDTVV 126
             A    + S AG Y C A NS G A       H+++ ++E   + P  E  Q       V
Sbjct: 1236 TAV---LPSHAGRYTCSARNSAGLAHK-----HISLTVQESPEIGPMAEEVQVVLHHGTV 1287

Query: 127  LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
            L C   +G P P++ W++ G ++      R+ ++  G L        DAG YQC+A+N A
Sbjct: 1288 LPC-EAQGFPRPSITWQREGVSIATG--HRLSVLSNGALKFSRVTLGDAGMYQCLAKNEA 1344

Query: 187  GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
            G        L + + P L     +  +  G  V+ +C   G P P+V W +      +  
Sbjct: 1345 GVAVGR-TRLVLQVPPVLSVPRMEYTSVLGQPVSLECVADGQPPPEVAWLKERRPV-IEG 1402

Query: 247  GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
              +++  +G+L + +   +D G Y+C A+N  G  S    L +  PP I+ +   ++V  
Sbjct: 1403 AHIRIFANGTLAIASTQRSDAGLYTCTAKNLAGRASHDMRLAIQVPPLISPAQTDLSVVQ 1462

Query: 307  GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
            G  A   C A G PEP + W   G      PG    KY  T +  G  ++   +    D+
Sbjct: 1463 GFQALLPCAAQGSPEPRISWEKNGTPVPNLPG----KY--TVLRSGELIIERAEVSWADA 1516

Query: 367  RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
                 C A N AGS+    +L++        P     P + TL         C A  TP 
Sbjct: 1517 -GVFTCVATNTAGSARQDSRLSINM-----RPAFKELPGDVTLNKGQNLALSCHAQGTPP 1570

Query: 427  PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
            P+I+W             + +   +L+++++  S +GTY C+A +  G
Sbjct: 1571 PVISWTVNNSPQ-TGATLDESGRSSLIIENVTTSHAGTYVCIAENSVG 1617



 Score =  156 bits (378), Expect = 4e-36
 Identities = 146/541 (26%), Positives = 226/541 (41%), Gaps = 31/541 (5%)

Query: 21   VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
            +TV  +   TL C A   P+P I WYK  V V        L AGG + L     R   D+
Sbjct: 913  LTVPVNGHLTLECLADSDPAPEIEWYKDEVKVQLGGRVQQL-AGGQY-LEIQEVRPE-DS 969

Query: 81   GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
            G+Y C  TN  G++ S   T+ + +L  + R       +  G   +L C     + +  V
Sbjct: 970  GLYSCVVTNMAGSS-SLFFTVEI-LLPPKIRESSSEVTTHVGQDALLLCEVEEDA-QATV 1026

Query: 141  YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
             W+K+G  +    D +  L+  G+L + D + +DAGRY C   N AG+    I  L++ +
Sbjct: 1027 TWRKDGFPIT--QDHKYTLLSEGSLRVHDVQLSDAGRYYCSVSNQAGSDHRGIY-LRVFV 1083

Query: 201  KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL--GRVKVLDDGSLR 258
             P +  GP +V    G      C   G P P V W+R+    ++    G  ++L  GSL 
Sbjct: 1084 APAISPGPFNVTVTAGMRAVLSCETTGIPPPKVSWKRNGKPLDVSQLSGAFRLLSSGSLV 1143

Query: 259  LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATG 318
            L +    DEG + C A N  G       + +  PP+I     +V     +     C   G
Sbjct: 1144 LLSPSDEDEGYFECTAVNDAGEERRVVEVILQVPPTIEDDVTAVTAVKMSPVALPCHVQG 1203

Query: 319  RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
            RP+PT+ W+  G +     G  R     T + +   VL       +  R T  CSA N A
Sbjct: 1204 RPQPTVVWTKSGAKLSSRGGTYR--VLPTGLLEITAVLP-----SHAGRYT--CSARNSA 1254

Query: 379  GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438
            G +     LTV    +  P           + +    V PC A   P P I W  EG ++
Sbjct: 1255 GLAHKHISLTVQESPEIGPMA-----EEVQVVLHHGTVLPCEAQGFPRPSITWQREGVSI 1309

Query: 439  IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAA 498
               HR +V ++G L    +   D+G Y C+A +  G  V    L++  P  P +   R  
Sbjct: 1310 ATGHRLSVLSNGALKFSRVTLGDAGMYQCLAKNEAGVAVGRTRLVLQVP--PVLSVPR-M 1366

Query: 499  DVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558
            + +S+ G P              ++W +  +     I G  + +F+  TL+  +T R+  
Sbjct: 1367 EYTSVLGQPVSLECVADGQPPPEVAWLKERR---PVIEGAHIRIFANGTLAIASTQRSDA 1423

Query: 559  G 559
            G
Sbjct: 1424 G 1424



 Score =  154 bits (373), Expect = 2e-35
 Identities = 157/610 (25%), Positives = 249/610 (40%), Gaps = 53/610 (8%)

Query: 11   APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG----VLVVSDTHRSILPAGGL 66
            AP I   P +VTV     A L+C   G P P + W + G    V  +S   R +L +G L
Sbjct: 1084 APAISPGPFNVTVTAGMRAVLSCETTGIPPPKVSWKRNGKPLDVSQLSGAFR-LLSSGSL 1142

Query: 67   FFLRATHGRVHSDAGVYWCEATNSYGTARS-RNATLHVAVLREEFRLEPESKQSAQGDTV 125
              L  +      D G + C A N  G  R      L V    E+   +  +  + +   V
Sbjct: 1143 VLLSPS----DEDEGYFECTAVNDAGEERRVVEVILQVPPTIED---DVTAVTAVKMSPV 1195

Query: 126  VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
             L C   +G P+P V W K+G  L   G +   ++  G L I     + AGRY C ARN+
Sbjct: 1196 ALPC-HVQGRPQPTVVWTKSGAKLSSRGGT-YRVLPTGLLEITAVLPSHAGRYTCSARNS 1253

Query: 186  AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
            AG     I +L +   P +    E+V           C   G P P + W+R   G ++ 
Sbjct: 1254 AGLAHKHI-SLTVQESPEIGPMAEEVQVVLHHGTVLPCEAQGFPRPSITWQRE--GVSIA 1310

Query: 246  LG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
             G R+ VL +G+L+   V L D G Y C A+N  G       L +  PP +++       
Sbjct: 1311 TGHRLSVLSNGALKFSRVTLGDAGMYQCLAKNEAGVAVGRTRLVLQVPPVLSVPRMEYTS 1370

Query: 305  ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
              G      C A G+P P + W  E  R +I      +  H     +G   L I  T ++
Sbjct: 1371 VLGQPVSLECVADGQPPPEVAWLKE-RRPVI------EGAHIRIFANG--TLAIASTQRS 1421

Query: 365  DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
            D+     C+A N AG +    +L +     + PP+I+   ++ ++     A+ PC A  +
Sbjct: 1422 DA-GLYTCTAKNLAGRASHDMRLAI-----QVPPLISPAQTDLSVVQGFQALLPCAAQGS 1475

Query: 425  PEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLK--DLDKSDSGTYTCVASSRHGKYVWSGA 481
            PEP I+W   G  +     +  V   G L+++  ++  +D+G +TCVA++  G       
Sbjct: 1476 PEPRISWEKNGTPVPNLPGKYTVLRSGELIIERAEVSWADAGVFTCVATNTAGSARQDSR 1535

Query: 482  LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541
            L ++  + P        DV+   G       H        +SW+ NN    S   G  ++
Sbjct: 1536 LSIN--MRPAFKEL-PGDVTLNKGQNLALSCHAQGTPPPVISWTVNN----SPQTGATLD 1588

Query: 542  VFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPV 601
               R +L   N   +  G  V          + ++ +  I  +  VR      L G + +
Sbjct: 1589 ESGRSSLIIENVTTSHAGTYVC---------IAENSVGSIRALSFVRVREPPVLKGEARM 1639

Query: 602  SDSVTVGDDS 611
            S +V  G  +
Sbjct: 1640 SQTVVQGSSA 1649



 Score =  142 bits (345), Expect = 4e-32
 Identities = 141/490 (28%), Positives = 203/490 (41%), Gaps = 49/490 (10%)

Query: 19  LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS 78
           LDV +    P +L+C +   P P + W+K G  ++S     +LP   +  +         
Sbjct: 75  LDVVLGH--PVSLSCESNAIPPPKLSWHKDGQKLMSGDGVVLLPGAQVLQIARVQ---KE 129

Query: 79  DAGVYWCEATNSYGTARSRNATLHVAV------LREEFRLEPESKQSAQGDTVVLECLPP 132
           DAG Y C+A N  G     +  LH+ V        EEF    E   +    TVVL C   
Sbjct: 130 DAGRYTCQAVNEAGEDH-MHFELHILVPPVITGATEEFM---EEMAAVVNSTVVLHC-DV 184

Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
            G P P V W K+GQ +  D   ++   DG  L +   + +D   Y C+A N  GT E  
Sbjct: 185 TGQPTPAVSWMKDGQPVQTDPQHQIS-KDGTQLHLLRVQVSDMAGYLCVAENKVGTVEK- 242

Query: 193 IATLKIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR-V 249
           + +L + + P  ITG   E+V    G  V+  C V   P P++ W R   G  +  G  +
Sbjct: 243 LFSLTVQVPP-RITGRMEEEVSVTEGRMVSLLCDVQAYPPPEITWTRD--GQVLAFGSGI 299

Query: 250 KVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS----INLSPNSVNV 304
            +L  G  L+L    L D G+Y C A NS G    S  L+VY  PS    ++ + + V  
Sbjct: 300 HILPGGQMLQLPRARLEDAGQYVCTATNSAGQDQKSILLSVYVRPSLKPRLDAASDLVTP 359

Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
           + G+    +C A G PEP + W   G +     G   D+Y    V  GV V         
Sbjct: 360 QVGSSVILSCEAHGVPEPEVTWYKNGLQLAPRNGFEMDRYQLEIV--GVQVA-------- 409

Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP-SNQTLPIKSMAVFPCTAIC 423
               T  C   N AG      +LTV       PP++      +    + S     C A  
Sbjct: 410 -DDGTYTCKVSNVAGQVDRTFRLTV-----HVPPVLEGSLWESLNYTLGSHVTLSCQASG 463

Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482
            P P I W  +G  +  + +   +  G  L L  L  +  G YTCVA +  G+     AL
Sbjct: 464 FPVPSITWLKDGTPIESSLQWQWSIRGNRLELGPLTLAHGGVYTCVAENSEGQTQKDYAL 523

Query: 483 LVDSPINPNI 492
            V   ++P I
Sbjct: 524 TVQ--VSPTI 531



 Score =  132 bits (318), Expect = 7e-29
 Identities = 125/471 (26%), Positives = 195/471 (41%), Gaps = 41/471 (8%)

Query: 31  LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
           L+C A G P P + WYK G+ +       +      + L     +V +D G Y C+ +N 
Sbjct: 367 LSCEAHGVPEPEVTWYKNGLQLAPRNGFEM----DRYQLEIVGVQV-ADDGTYTCKVSNV 421

Query: 91  YGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
            G   R+   T+HV  + E    E  S     G  V L C    G P P++ W K+G T 
Sbjct: 422 AGQVDRTFRLTVHVPPVLEGSLWE--SLNYTLGSHVTLSC-QASGFPVPSITWLKDG-TP 477

Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG-- 207
           +         + G  L +        G Y C+A N+ G  +   A L + + P ++    
Sbjct: 478 IESSLQWQWSIRGNRLELGPLTLAHGGVYTCVAENSEGQTQKDYA-LTVQVSPTILDSEH 536

Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA----GGGNMPLGRVKVLDDGSLRLDNVI 263
           P +V A  G  ++ +C+  G+P P + W +      G  N  +  V   +  +L L  + 
Sbjct: 537 PSEVSAPMGEELSLECQATGNPTPHLSWLKDGVIVEGSDNRHI--VATPEGSALTLLRLS 594

Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPPSI---NLSPNSVNVESGNVARFTCTATGRP 320
             D G Y+C A +  G  +    L V  PPSI      P  V V   +V    C   G P
Sbjct: 595 PDDSGTYTCLAVSPAGRQTKIYTLFVLVPPSIAGETTVPREVPVTQDSVVTLECQVAGSP 654

Query: 321 EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGS 380
            P + W   G+  ++ P         T +    +VL I+    +DS     C A + AG 
Sbjct: 655 PPQISWLKNGHPLLLSP--------RTRLLSADSVLRISPVQLSDS-GVYTCVARSQAGL 705

Query: 381 SFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK-SMAVFPCTAICTPEPIIAWYFEGEALI 439
           +    +L+       PP +    P      ++ S+    C A   P P + W+ +G+ L 
Sbjct: 706 A----ELSYDVQVQVPPGVDHVEPVEPVTIVQGSLVTLSCEARGVPPPTLTWFKDGQPL- 760

Query: 440 QNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
            +  RN+  DG    L L D+  SD+G Y+CVAS++ G    +  L V  P
Sbjct: 761 -SLHRNLLLDGQETRLQLPDVATSDAGLYSCVASNQAGSSTKTFNLTVLEP 810



 Score =  116 bits (278), Expect = 5e-24
 Identities = 89/282 (31%), Positives = 142/282 (50%), Gaps = 16/282 (5%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFFLR 70
            P I     D++V +   A L C A GSP P I W K G  V +   + ++L +G L   R
Sbjct: 1449 PLISPAQTDLSVVQGFQALLPCAAQGSPEPRISWEKNGTPVPNLPGKYTVLRSGELIIER 1508

Query: 71   ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
            A      +DAGV+ C ATN+ G+AR +++ L +  +R  F+  P      +G  + L C 
Sbjct: 1509 AEVS--WADAGVFTCVATNTAGSAR-QDSRLSIN-MRPAFKELPGDVTLNKGQNLALSC- 1563

Query: 131  PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
              +G+P P + W  N         + +      +L+I++   + AG Y CIA N+ G+  
Sbjct: 1564 HAQGTPPPVISWTVNNSP---QTGATLDESGRSSLIIENVTTSHAGTYVCIAENSVGSIR 1620

Query: 191  SAIATLKIHIKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
             A++ +++  +P ++ G E  ++QT   GSS    C + GDP P + W R  G   +   
Sbjct: 1621 -ALSFVRVR-EPPVLKG-EARMSQTVVQGSSAILDCPIHGDPSPVLQWLRD-GHPLLRSH 1676

Query: 248  RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
            R++ L +GSL + ++  ADEGEY C AE+  G    +  L V
Sbjct: 1677 RIQALLNGSLVIYSINAADEGEYQCLAESEAGTAERTITLKV 1718



 Score = 87.8 bits (208), Expect = 2e-15
 Identities = 66/200 (33%), Positives = 92/200 (46%), Gaps = 14/200 (7%)

Query: 3    DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
            D  ++    P   E P DVT+ + Q   L+C A G+P P I W        S    + L 
Sbjct: 1533 DSRLSINMRPAFKELPGDVTLNKGQNLALSCHAQGTPPPVISWTVNN----SPQTGATLD 1588

Query: 63   AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRN--ATLHVAVLREEFRLEPESKQSA 120
              G   L        S AG Y C A NS G+ R+ +        VL+ E R+   S+   
Sbjct: 1589 ESGRSSL-IIENVTTSHAGTYVCIAENSVGSIRALSFVRVREPPVLKGEARM---SQTVV 1644

Query: 121  QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
            QG + +L+C P  G P P + W ++G  LL     R+  +  G+LVI      D G YQC
Sbjct: 1645 QGSSAILDC-PIHGDPSPVLQWLRDGHPLL--RSHRIQALLNGSLVIYSINAADEGEYQC 1701

Query: 181  IARNAAGTRESAIATLKIHI 200
            +A + AGT E  I TLK+ +
Sbjct: 1702 LAESEAGTAERTI-TLKVQV 1720


>UniRef50_UPI0000E460A7 Cluster: PREDICTED: similar to
            OTTHUMP00000065631; n=2; Strongylocentrotus
            purpuratus|Rep: PREDICTED: similar to OTTHUMP00000065631
            - Strongylocentrotus purpuratus
          Length = 3664

 Score =  182 bits (442), Expect = 7e-44
 Identities = 145/476 (30%), Positives = 219/476 (46%), Gaps = 33/476 (6%)

Query: 5    YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
            YV+  E P I            Q ATL+C   G P P I W+KG   +   T+  I P G
Sbjct: 791  YVSYHEPPRIQMTQYRYLTPPSQKATLSCPTSGVPPPEITWFKGDRDLTRVTYTRIWPNG 850

Query: 65   GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GD 123
             L  +    G   SD+G Y C ATN  G     + T+H+ V      L+P        G 
Sbjct: 851  DLDIM----GVQDSDSGSYTCYATNEAGVV---SETVHLEVGSSPIILQPPIDLGVNYGM 903

Query: 124  TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
             V + C+   G P P V W+K GQ+ L D + R+ + + GNL I+D +  D+G Y C+A 
Sbjct: 904  NVSVTCIA-MGHPPPAVTWRKVGQSHL-DINPRITMTEDGNLFIRDMQVEDSGTYVCVAH 961

Query: 184  NAAGTRESAIATLKIH--IKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLWRRSAG 240
            N  G+ E++ A L+I   I+P +    ++ V      V  +C V  G+P P V W  S+ 
Sbjct: 962  NEHGSTEAS-AQLRITNLIQPQISATSQEEVVVVEDDVVVRCNVISGNPPPTVTWFHSSE 1020

Query: 241  GGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
                    R+++  DGSL +   +++D G Y+C AEN++G  +    + V++PPSI+ + 
Sbjct: 1021 RLYPEYSPRLELFPDGSLGIRGAVMSDAGNYTCVAENAIGNDTKITRIRVHNPPSISGTE 1080

Query: 300  NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
             S  V         C A G P P + W ++  +TI  P +     H +A       LT++
Sbjct: 1081 TSYTVIHHESVTLLCPAAGHPPPLIEW-IKNGQTI--PNLG---LHQSA-------LTLS 1127

Query: 360  DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419
               + D+  T +C   N AG S +   L +         + T G  N T         PC
Sbjct: 1128 YVTEQDA-GTYICRVSNLAGFSEIEITLFILVPPAH-EGVETTGVVNVTQ--GDSVTLPC 1183

Query: 420  TAICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
                TP P I+W+ +   L +  R   V  DG LV++ +  ++ G Y CVAS+  G
Sbjct: 1184 NVRGTPPPQISWFKDNLPLPEAGRNFYVNTDGGLVIQQMSVAEEGQYRCVASNIAG 1239



 Score =  175 bits (427), Expect = 5e-42
 Identities = 125/462 (27%), Positives = 200/462 (43%), Gaps = 28/462 (6%)

Query: 15   IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74
            +E+   +T+   Q  +L C   G+P P + WYK G   +S T   ++    L      + 
Sbjct: 1442 VEETFSITIG--QTVSLPCEVTGTPPPIVTWYKSGN-PISVTSSMVITQDSLDI----YS 1494

Query: 75   RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRG 134
                D G+Y C A+N  G   +RN  L + ++    +  P ++ +  G  + LEC    G
Sbjct: 1495 TRPFDTGIYQCVASNVAGNV-TRNFRL-IVMIPPSIQDGPATRTTEVGAHIELECRAD-G 1551

Query: 135  SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194
             P P++ W K+G+ L    D R+     G L I +  Q D+G Y C   N AG + S   
Sbjct: 1552 IPLPDITWYKDGEPLGTYNDPRLRKTAFGTLQIVNVDQEDSGEYACYVSNDAG-KASKFV 1610

Query: 195  TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254
            TL +++ P L+  P+   +   + VT QC   G P PDV W ++    N    R  +   
Sbjct: 1611 TLTVNLAPILLDSPDSYTSLIRNPVTLQCLAAGFPPPDVTWLKNGAPLNQEDVRYYITPS 1670

Query: 255  GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP-SINLSPNSVNVESGNVARFT 313
             SL + + +  D G Y+C   N+ G       LTVY PP SIN    S +V   N     
Sbjct: 1671 NSLLIASTMREDSGIYTCNVSNTAGHQYKHMELTVYLPPTSINSGDTSYDVTLNNPVSLP 1730

Query: 314  CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
            C     P PT+ W  +G    + P  +   Y        + +  + D+          C 
Sbjct: 1731 CEVQSYPPPTITWLKDGR---VIP-YTNSHYRIQPSSLDIPMAVVRDS------GVYTCI 1780

Query: 374  AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF 433
            A N  G+     ++ V     + PP I+ GP   T  +      PC +I  P P+  W  
Sbjct: 1781 ATNIVGNISRNYQINV-----QVPPYISPGPDTITAYLGQNVTLPCDSIGVPTPMTMWDK 1835

Query: 434  EGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
             G  L   + R +  ++G+L++ D+ + D+G Y C+  ++ G
Sbjct: 1836 SGLQLNYDDSRFHKLDEGSLIISDVRELDAGAYYCLVVNQAG 1877



 Score =  173 bits (421), Expect = 2e-41
 Identities = 138/479 (28%), Positives = 199/479 (41%), Gaps = 30/479 (6%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-DTHRSILPAGGLFFLR 70
            P I       TV  H+  TL C A G P P I W K G  + +   H+S L    +    
Sbjct: 1074 PSISGTETSYTVIHHESVTLLCPAAGHPPPLIEWIKNGQTIPNLGLHQSALTLSYV---- 1129

Query: 71   ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLEC 129
                    DAG Y C  +N  G +     TL + V      +E     +  QGD+V L C
Sbjct: 1130 -----TEQDAGTYICRVSNLAGFSEIE-ITLFILVPPAHEGVETTGVVNVTQGDSVTLPC 1183

Query: 130  LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
               RG+P P + W K+   L   G +     DGG LVIQ     + G+Y+C+A N AG  
Sbjct: 1184 -NVRGTPPPQISWFKDNLPLPEAGRNFYVNTDGG-LVIQQMSVAEEGQYRCVASNIAGNV 1241

Query: 190  ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249
               +  + I + P +  G  +     G S+   C   G P+P+V+W++     ++    V
Sbjct: 1242 SKDVR-ITILVPPSIEPGNTEYAVVAGGSIILSCEAYGIPMPEVVWQKDGAQLSIATRNV 1300

Query: 250  KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309
            ++LD GSL++D       G Y+C   N  G+ +    L+V  PP I        V  G  
Sbjct: 1301 RILDLGSLQIDVTSEEHTGTYTCLVTNEAGSTNRLITLSVIVPPRIFDGQTQYTVVQGQA 1360

Query: 310  ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
                C ATG P PT+ WS EG   I  P ++   Y    +   +T+  +  TD      T
Sbjct: 1361 IILHCPATGTPPPTITWSKEG---IAIP-LNDPHYDVDEIAGTLTMFGVLPTD----FGT 1412

Query: 370  IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ-TLPIKSMAVFPCTAICTPEPI 428
              C   N  GS +    L+V        P+I        ++ I      PC    TP PI
Sbjct: 1413 YKCVVRNDGGSVYKDITLSV-----HVAPVIEEAVEETFSITIGQTVSLPCEVTGTPPPI 1467

Query: 429  IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
            + WY  G  +       +T D +L +      D+G Y CVAS+  G    +  L+V  P
Sbjct: 1468 VTWYKSGNPISVTSSMVITQD-SLDIYSTRPFDTGIYQCVASNVAGNVTRNFRLIVMIP 1525



 Score =  172 bits (419), Expect = 4e-41
 Identities = 140/457 (30%), Positives = 198/457 (43%), Gaps = 32/457 (7%)

Query: 21   VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
            VT    Q   L C A G P+P I W K G  V S     ++ + G+  +        SDA
Sbjct: 3114 VTTQIGQSVRLFCDATGVPTPEILWQKDGQRV-SPMEGFLIISDGMLQINDAQP---SDA 3169

Query: 81   GVYWCEATNSYGTARSRNAT-LHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
            G Y C A N  G    +    +H      E     E +  A   +V LEC    G P+PN
Sbjct: 3170 GRYDCIAKNGAGADVFKVILEVHEPPQIAETTKTYEIRVDA---SVELECRVG-GIPKPN 3225

Query: 140  VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG--TRESAIATLK 197
            + W  NG+ L   G   + L +G NL I   R  D+G Y C+A+N AG    E  +  L 
Sbjct: 3226 IRWLFNGREL---GAQSLKLANG-NLKIPVVRAEDSGAYTCLAQNDAGFAQAERILVVLD 3281

Query: 198  IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257
            +   P       ++           C   G P P+V WR+  G    P GR+ + ++  L
Sbjct: 3282 VPRLPRPPREQSEMTISVNRRAVLTCPADGYPPPEVTWRKD-GILVEPAGRITMTENHEL 3340

Query: 258  RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
             +D V  +D G Y+C A NS+G+   + YLTV   P+    PN V + +GN     C A 
Sbjct: 3341 IIDRVQESDSGTYTCVATNSIGSNRLNFYLTVQVAPTFTHFPNDVELAAGNRLELICEAI 3400

Query: 318  GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
            G P P + W V G   I  P            FDG +VL I +  K+DS  T +C A N 
Sbjct: 3401 GVPMPDIAWLVNGTEMIPNP----------PTFDGRSVLAIGNVQKSDS-GTYMCRAENI 3449

Query: 378  AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437
             G      +  +T+   R PP I   PS+ TL +   AV  C     P+P + W      
Sbjct: 3450 LGV-----RTAITAVRVRVPPRIHRIPSDTTLTLGERAVLNCAVNGDPKPEVTWLKNNRP 3504

Query: 438  LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
            +        ++DG+L++     SD+G Y C A + +G
Sbjct: 3505 VALTDTMQQSSDGSLIIAPTAISDAGFYKCQALNLYG 3541



 Score =  165 bits (400), Expect = 9e-39
 Identities = 132/459 (28%), Positives = 188/459 (40%), Gaps = 24/459 (5%)

Query: 18   PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
            P+ +++       L C A G P P IRWYK G LV  +     +   G         R+H
Sbjct: 2833 PMMMSINEDDSTQLGCHASGYPPPTIRWYKDGRLVTHNEPGVAVSNSGEVLRINRVNRIH 2892

Query: 78   SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSP 136
              AG + C A++  G   S++  L+V V  E    E P +        + L C P    P
Sbjct: 2893 --AGQFTCVASSIVGNI-SKSYVLNVRVRPEIEGAEFPHNVSVVNNMGIELRC-PTVAIP 2948

Query: 137  EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
             P + W K+G  L       +   DG  L I +A+  D G YQC+A N AG  E  +  L
Sbjct: 2949 VPEIVWYKDGHRLHPFQSGVLISPDGTTLRIPNAQLHDEGVYQCVATNVAG-EEMKLFNL 3007

Query: 197  KIHIKPYLITG-PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
            +I + P +++  P  +    G S T  C   G P P V W ++    +    R  +   G
Sbjct: 3008 QIDVPPVIVSREPNQIAVIAGGSTTIDCESYGVPKPTVTWTKNNAFISPASIRYDIDPAG 3067

Query: 256  SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315
             L +  V +ADEG + C   NS G V+    L V   P+I      V  + G   R  C 
Sbjct: 3068 LLHIATVTVADEGVFECFVSNSAGNVTRRIDLQVQVQPTITPGRGRVTTQIGQSVRLFCD 3127

Query: 316  ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
            ATG P P + W  +G R     G          + DG  +L IND   +D+     C A 
Sbjct: 3128 ATGVPTPEILWQKDGQRVSPMEGF-------LIISDG--MLQINDAQPSDA-GRYDCIAK 3177

Query: 376  NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG 435
            N AG+   +  L V       PP I        + + +     C     P+P I W F G
Sbjct: 3178 NGAGADVFKVILEV-----HEPPQIAETTKTYEIRVDASVELECRVGGIPKPNIRWLFNG 3232

Query: 436  EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
              L     +    +G L +  +   DSG YTC+A +  G
Sbjct: 3233 RELGAQSLK--LANGNLKIPVVRAEDSGAYTCLAQNDAG 3269



 Score =  158 bits (384), Expect = 7e-37
 Identities = 147/527 (27%), Positives = 218/527 (41%), Gaps = 35/527 (6%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG--VLVVSDTHRSILPAGGLFFL 69
            P I + P   T        L CRA G P P I WYK G  +   +D        G L  +
Sbjct: 1526 PSIQDGPATRTTEVGAHIELECRADGIPLPDITWYKDGEPLGTYNDPRLRKTAFGTLQIV 1585

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
                     D+G Y C  +N  G A S+  TL V  L       P+S  S   + V L+C
Sbjct: 1586 NVDQ----EDSGEYACYVSNDAGKA-SKFVTLTVN-LAPILLDSPDSYTSLIRNPVTLQC 1639

Query: 130  LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
            L   G P P+V W KNG  L  + D R ++    +L+I    + D+G Y C   N AG +
Sbjct: 1640 LAA-GFPPPDVTWLKNGAPLNQE-DVRYYITPSNSLLIASTMREDSGIYTCNVSNTAGHQ 1697

Query: 190  ESAIATLKIHIKPYLI-TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
               +  L +++ P  I +G         + V+  C V   P P + W +   G  +P   
Sbjct: 1698 YKHME-LTVYLPPTSINSGDTSYDVTLNNPVSLPCEVQSYPPPTITWLKD--GRVIPYTN 1754

Query: 249  VKV-LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESG 307
                +   SL +   ++ D G Y+C A N VG +S +  + V  PP I+  P+++    G
Sbjct: 1755 SHYRIQPSSLDIPMAVVRDSGVYTCIATNIVGNISRNYQINVQVPPYISPGPDTITAYLG 1814

Query: 308  NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
                  C + G P P   W   G +          ++H   + +G   L I+D  + D+ 
Sbjct: 1815 QNVTLPCDSIGVPTPMTMWDKSGLQL----NYDDSRFHK--LDEGS--LIISDVRELDA- 1865

Query: 368  NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427
                C  VN AG+   R  LTV       P II   P      + +    PC A  TP P
Sbjct: 1866 GAYYCLVVNQAGADTRRITLTVKD----APRIINELPEVMEQIMNTEVRIPCQATGTPRP 1921

Query: 428  IIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
             ++W+ +G  + Q     V  D TL++  L   D+G Y C A S  G    S  + +D+ 
Sbjct: 1922 QVSWFKDGRPIEQLRGYTVLGDNTLLISSLQPYDNGRYECRAQSESG--FDSIDVFIDTQ 1979

Query: 488  INPNIHFFRAAD---VSSLPGPPTKPITHNVTDT--SVTLSWSQNNK 529
            + P+I      D   V       T  +  NVTD+     ++W QN +
Sbjct: 1980 VRPHIAGENTPDDPVVVFTEEDQTVILECNVTDSHPPAEVTWYQNGQ 2026



 Score =  155 bits (377), Expect = 5e-36
 Identities = 140/526 (26%), Positives = 235/526 (44%), Gaps = 38/526 (7%)

Query: 16   EQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74
            + P+ V     Q   L C    S  PA + WY+ G  +++     I    G   LR  + 
Sbjct: 1991 DDPVVVFTEEDQTVILECNVTDSHPPAEVTWYQNGQAILARADIGIHFETGDTSLRLPYL 2050

Query: 75   RVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
            R   DAG Y CEATN  G++ R  +  +HV  +    R E  + Q   G ++ + C    
Sbjct: 2051 RPE-DAGHYHCEATNGQGSSQRHFSLEVHVGPVIRNRRQEQVTVQV--GHSITIHC-EAS 2106

Query: 134  GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
            G P+  + W   G   +   +SR H+   G+L +++ +  D+G + CIA+N+AG  ++ +
Sbjct: 2107 GVPDARILWMF-GDIAISSQNSRYHIASNGSLHLREVQVIDSGVFTCIAKNSAGN-DTRV 2164

Query: 194  ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD 253
              + + + P +  G  D+V    SSV   C   G P P++ W ++    N+    ++ L 
Sbjct: 2165 VNINVIVPPSINDGTSDIVRTLSSSVILPCESAGVPFPEITWYKNGAPLNLSNPNLEKLF 2224

Query: 254  DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN-SVNVESG--NVA 310
             GSLR+ +V   D G Y C A N  G       L ++ PPS  L P+ S NV +G     
Sbjct: 2225 SGSLRIRSVEEEDSGVYRCVAVNQAGHDYKMLTLWIHTPPS--LQPDASRNVSTGVDEKV 2282

Query: 311  RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
               C  +G P+P   W ++ NR ++   M+  K     + DG   L I D +  D R + 
Sbjct: 2283 IIPCNISGSPKPQYRW-LKNNRELL---MNYGKME--LLEDG--SLMIRDVESID-RGSY 2333

Query: 371  VCSAVNYAG--SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT---P 425
             C A N  G  S  +R +++V        P IT   +    P+          + T   P
Sbjct: 2334 TCEATNAVGVLSRDIRLEVSVA-------PKITGSKTPVEYPVGQYDSIELQCMVTDAFP 2386

Query: 426  EPIIAWYFEGEALI-QNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
             PII WY   E L  Q     + + G TL +  ++ +++G Y C A++  G  + S    
Sbjct: 2387 PPIIKWYKGDETLTGQEEAVTIKDQGITLEIGSVNIANAGEYYCTATNDAG--MASMNWT 2444

Query: 484  VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
            +D  + P+I   +   ++++       +     + + T++W ++NK
Sbjct: 2445 IDVQVTPSILNGQDEYLTTVQNIDITLLCEAEGNPTPTITWERDNK 2490



 Score =  155 bits (377), Expect = 5e-36
 Identities = 127/477 (26%), Positives = 201/477 (42%), Gaps = 30/477 (6%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            E P I E      +       L CR GG P P IRW   G  + +   +S+  A G   +
Sbjct: 3193 EPPQIAETTKTYEIRVDASVELECRVGGIPKPNIRWLFNGRELGA---QSLKLANGNLKI 3249

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT-VVLE 128
                     D+G Y C A N  G A++    + + V R       +S+ +   +   VL 
Sbjct: 3250 PVVRAE---DSGAYTCLAQNDAGFAQAERILVVLDVPRLPRPPREQSEMTISVNRRAVLT 3306

Query: 129  CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
            C P  G P P V W+K+G  +L +   R+ + +   L+I   +++D+G Y C+A N+ G+
Sbjct: 3307 C-PADGYPPPEVTWRKDG--ILVEPAGRITMTENHELIIDRVQESDSGTYTCVATNSIGS 3363

Query: 189  RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
                   L + + P     P DV    G+ +   C   G P+PD+ W  +   G   +  
Sbjct: 3364 NRLNFY-LTVQVAPTFTHFPNDVELAAGNRLELICEAIGVPMPDIAWLVN---GTEMIPN 3419

Query: 249  VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESG 307
                D  S L + NV  +D G Y C AEN +G  +A   + V  PP I+  P+   +  G
Sbjct: 3420 PPTFDGRSVLAIGNVQKSDSGTYMCRAENILGVRTAITAVRVRVPPRIHRIPSDTTLTLG 3479

Query: 308  NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
              A   C   G P+P + W ++ NR +      +     + +   +    I+D       
Sbjct: 3480 ERAVLNCAVNGDPKPEVTW-LKNNRPVALTDTMQQSSDGSLI---IAPTAISDA------ 3529

Query: 368  NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427
                C A+N  G   V   L + S   RP  ++   P N T+      +  C A   PEP
Sbjct: 3530 GFYKCQALNLYGLDEVSYHLEIQS---RPMFVVE--PQNTTVSHGENVLLDCIAQGEPEP 3584

Query: 428  IIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
             + W  EG  ++   R  +  + TL +     +DSG Y C+A ++ G+ V +  L V
Sbjct: 3585 SMRWQKEGFRVLPVGRVAILPNNTLKIVAAQLTDSGAYMCLAENQMGRAVMTIHLTV 3641



 Score =  152 bits (368), Expect = 6e-35
 Identities = 121/461 (26%), Positives = 188/461 (40%), Gaps = 24/461 (5%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
            +V+    +   + C   GSP P  RW K    ++ +  +  L   G   +R        D
Sbjct: 2273 NVSTGVDEKVIIPCNISGSPKPQYRWLKNNRELLMNYGKMELLEDGSLMIRDVES---ID 2329

Query: 80   AGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSPEP 138
             G Y CEATN+ G   SR+  L V+V  +    + P      Q D++ L+C+     P P
Sbjct: 2330 RGSYTCEATNAVGVL-SRDIRLEVSVAPKITGSKTPVEYPVGQYDSIELQCMVTDAFPPP 2388

Query: 139  NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
             + W K  +TL    ++      G  L I      +AG Y C A N AG   S   T+ +
Sbjct: 2389 IIKWYKGDETLTGQEEAVTIKDQGITLEIGSVNIANAGEYYCTATNDAGMA-SMNWTIDV 2447

Query: 199  HIKPYLITGPEDVVAQTGS-SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257
             + P ++ G ++ +    +  +T  C   G+P P + W R      +      + +DGSL
Sbjct: 2448 QVTPSILNGQDEYLTTVQNIDITLLCEAEGNPTPTITWERDNKPLELRDSHYLIGEDGSL 2507

Query: 258  RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
            R+      D G Y C A N++G    + +L V  PP  +     V +         C A 
Sbjct: 2508 RITAPQHTDSGGYVCVASNNIGYAIKNFHLVVKIPPKTSTQQEVVTIGLRQSVTLRCQAA 2567

Query: 318  GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
            G P PT+ W  +    +  P  +R    A ++      LTIN T + DS     C A N 
Sbjct: 2568 GFPAPTISWRKD---NLPIPLSTR----AFSISSNGGSLTINSTREGDS-GIYSCIASNE 2619

Query: 378  AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM----AVFPCTAICTPEPIIAWYF 433
             G       L +      PP I+     N+   ++ +       PC     P+P +AW F
Sbjct: 2620 VGEQ----SLDILLKVQEPPIILGELEVNRMQHVQLVEGDDIELPCPTTGYPKPRVAW-F 2674

Query: 434  EGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
                ++      + +DGTLV+      D+G YTC A +  G
Sbjct: 2675 RDNRILSPPEYKIKDDGTLVIPGAMPFDAGVYTCSAVNEAG 2715



 Score =  151 bits (366), Expect = 1e-34
 Identities = 143/538 (26%), Positives = 235/538 (43%), Gaps = 42/538 (7%)

Query: 21   VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFFLRATHGRVHSD 79
            VT+   Q  TL C+A G P+P I W K  + +   T   SI   GG   + +T      D
Sbjct: 2552 VTIGLRQSVTLRCQAAGFPAPTISWRKDNLPIPLSTRAFSISSNGGSLTINSTR---EGD 2608

Query: 80   AGVYWCEATNSYGTARSRNATLHVA----VLREEFRLEPESKQSAQGDTVVLECLPPRGS 135
            +G+Y C A+N  G  +S +  L V     +L E      +  Q  +GD + L C P  G 
Sbjct: 2609 SGIYSCIASNEVGE-QSLDILLKVQEPPIILGELEVNRMQHVQLVEGDDIELPC-PTTGY 2666

Query: 136  PEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195
            P+P V W ++ + L         + D G LVI  A   DAG Y C A N AG    +I  
Sbjct: 2667 PKPRVAWFRDNRIL---SPPEYKIKDDGTLVIPGAMPFDAGVYTCSAVNEAGNSSISI-N 2722

Query: 196  LKIHIKPYLITG--PEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGNMPLGRVKVL 252
            + + + P L+    P D++    +     C +    P+  ++W++  G        +++ 
Sbjct: 2723 VTVMVPPLLVDAYRPVDIIVILNNPARLYCEIDISIPMASIVWQKD-GISLREDSNIRIS 2781

Query: 253  DDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN----LSPNSVNVESG 307
             DG  L ++ V + +EG Y+C A N+ G  +    LTV+ PP       ++P  +++   
Sbjct: 2782 RDGQILEINQVQVNNEGRYTCIATNNAGNATKFFGLTVHVPPIFPDGNPVNPMMMSINED 2841

Query: 308  NVARFTCTATGRPEPTMFWSVEGNR-TIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
            +  +  C A+G P PT+ W  +G   T   PG+        AV +   VL IN  ++  +
Sbjct: 2842 DSTQLGCHASGYPPPTIRWYKDGRLVTHNEPGV--------AVSNSGEVLRINRVNRIHA 2893

Query: 367  RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTP 425
                 C A +  G+     K  V +   RP       P N ++ + +M +   C  +  P
Sbjct: 2894 -GQFTCVASSIVGNI---SKSYVLNVRVRPEIEGAEFPHNVSV-VNNMGIELRCPTVAIP 2948

Query: 426  EPIIAWYFEGEALIQNHRRN-VTNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
             P I WY +G  L        ++ DGT L + +    D G Y CVA++  G+ +    L 
Sbjct: 2949 VPEIVWYKDGHRLHPFQSGVLISPDGTTLRIPNAQLHDEGVYQCVATNVAGEEMKLFNLQ 3008

Query: 484  VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541
            +D P  P I       ++ + G  T     +      T++W++NN   S + + Y ++
Sbjct: 3009 IDVP--PVIVSREPNQIAVIAGGSTTIDCESYGVPKPTVTWTKNNAFISPASIRYDID 3064



 Score =  148 bits (359), Expect = 8e-34
 Identities = 112/413 (27%), Positives = 179/413 (43%), Gaps = 22/413 (5%)

Query: 81  GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
           GVY C A N  G+ARS   T             P +     G   V+ C     + E N+
Sbjct: 592 GVYSCIAENEEGSARSE--TYLDITEPPPVIARPYNTSVLPGSDGVMSCFIS-STVEYNI 648

Query: 141 YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
            W K    +   G +R+ L++ G+LVIQD    DAG Y+C A N  G  E  +  L +  
Sbjct: 649 TWDKPNTLVSLQGHNRVSLMNNGSLVIQDVHPGDAGSYRCRAWNEGGVTEEHV-YLYVQE 707

Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLD 260
           +P +     +V   +  ++T +C   G P P++ W +   G  +P+       +   ++ 
Sbjct: 708 RPQINAYQGNVTFTSSQNITLRCSANGYPHPELRWLKD--GQELPIVPGTRRGEIIHQIF 765

Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
           N    D+G Y+C A N+ G+   + Y++ ++PP I ++           A  +C  +G P
Sbjct: 766 NASREDQGIYTCLASNTAGSDLLNVYVSYHEPPRIQMTQYRYLTPPSQKATLSCPTSGVP 825

Query: 321 EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGS 380
            P + W  +G+R      ++R  Y        + ++ + D+D      +  C A N AG 
Sbjct: 826 PPEITW-FKGDR-----DLTRVTYTRIWPNGDLDIMGVQDSDS----GSYTCYATNEAGV 875

Query: 381 SFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ 440
                 L V S      PII   P +  +         C A+  P P + W   G++ + 
Sbjct: 876 VSETVHLEVGSS-----PIILQPPIDLGVNYGMNVSVTCIAMGHPPPAVTWRKVGQSHLD 930

Query: 441 -NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
            N R  +T DG L ++D+   DSGTY CVA + HG    S  L + + I P I
Sbjct: 931 INPRITMTEDGNLFIRDMQVEDSGTYVCVAHNEHGSTEASAQLRITNLIQPQI 983



 Score =  142 bits (345), Expect = 4e-32
 Identities = 130/491 (26%), Positives = 204/491 (41%), Gaps = 28/491 (5%)

Query: 6    VTSGEAPYIIE--QPLDVTVARHQPATLNCRAGGS-PSPAIRWYKGGVLVVSDTHRSILP 62
            VT    P +++  +P+D+ V  + PA L C    S P  +I W K G+ +  D++  I  
Sbjct: 2723 VTVMVPPLLVDAYRPVDIIVILNNPARLYCEIDISIPMASIVWQKDGISLREDSNIRISR 2782

Query: 63   AGGLFFLRATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVA-VLREEFRLEPESKQSA 120
             G +  L     +V+++ G Y C ATN+ G A +    T+HV  +  +   + P      
Sbjct: 2783 DGQI--LEINQVQVNNE-GRYTCIATNNAGNATKFFGLTVHVPPIFPDGNPVNPMMMSIN 2839

Query: 121  QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
            + D+  L C    G P P + W K+G+ +  +         G  L I    +  AG++ C
Sbjct: 2840 EDDSTQLGC-HASGYPPPTIRWYKDGRLVTHNEPGVAVSNSGEVLRINRVNRIHAGQFTC 2898

Query: 181  IARNAAGTRESAIATLKIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238
            +A +  G    +   L + ++P +     P +V       +  +C     P+P+++W + 
Sbjct: 2899 VASSIVGNISKSYV-LNVRVRPEIEGAEFPHNVSVVNNMGIELRCPTVAIPVPEIVWYKD 2957

Query: 239  AGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-N 296
                +     V +  DG+ LR+ N  L DEG Y C A N  G       L +  PP I +
Sbjct: 2958 GHRLHPFQSGVLISPDGTTLRIPNAQLHDEGVYQCVATNVAGEEMKLFNLQIDVPPVIVS 3017

Query: 297  LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
              PN + V +G      C + G P+PT+ W+   N   I P   R       +    TV 
Sbjct: 3018 REPNQIAVIAGGSTTIDCESYGVPKPTVTWTK--NNAFISPASIRYDIDPAGLLHIATV- 3074

Query: 357  TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416
            T+ D           C   N AG+   R  L V     +  P IT G    T  I     
Sbjct: 3075 TVAD------EGVFECFVSNSAGNVTRRIDLQV-----QVQPTITPGRGRVTTQIGQSVR 3123

Query: 417  FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476
              C A   P P I W  +G+ +       + +DG L + D   SD+G Y C+A +  G  
Sbjct: 3124 LFCDATGVPTPEILWQKDGQRVSPMEGFLIISDGMLQINDAQPSDAGRYDCIAKNGAGAD 3183

Query: 477  VWSGALLVDSP 487
            V+   L V  P
Sbjct: 3184 VFKVILEVHEP 3194



 Score =  142 bits (344), Expect = 5e-32
 Identities = 131/482 (27%), Positives = 194/482 (40%), Gaps = 37/482 (7%)

Query: 2    SDDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI- 60
            S+ Y+   E P +I +P + +V       ++C    +    I W K   LV    H  + 
Sbjct: 607  SETYLDITEPPPVIARPYNTSVLPGSDGVMSCFISSTVEYNITWDKPNTLVSLQGHNRVS 666

Query: 61   LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA 120
            L   G   ++  H     DAG Y C A N  G     +  L+V   R +      +    
Sbjct: 667  LMNNGSLVIQDVH---PGDAGSYRCRAWNE-GGVTEEHVYLYVQE-RPQINAYQGNVTFT 721

Query: 121  QGDTVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179
                + L C    G P P + W K+GQ L +  G  R  ++      I +A + D G Y 
Sbjct: 722  SSQNITLRC-SANGYPHPELRWLKDGQELPIVPGTRRGEIIH----QIFNASREDQGIYT 776

Query: 180  CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
            C+A N AG+ +     +  H  P +       +       T  C   G P P++ W +  
Sbjct: 777  CLASNTAGS-DLLNVYVSYHEPPRIQMTQYRYLTPPSQKATLSCPTSGVPPPEITWFK-- 833

Query: 240  GGGNMPLGRV---KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
              G+  L RV   ++  +G L +  V  +D G Y+C A N  G VS + +L V   P I 
Sbjct: 834  --GDRDLTRVTYTRIWPNGDLDIMGVQDSDSGSYTCYATNEAGVVSETVHLEVGSSPIIL 891

Query: 297  LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI-IFPGMSRDKYHATAVFDGVTV 355
              P  + V  G     TC A G P P + W   G   + I P         T   DG   
Sbjct: 892  QPPIDLGVNYGMNVSVTCIAMGHPPPAVTWRKVGQSHLDINP-------RITMTEDG--N 942

Query: 356  LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
            L I D    DS  T VC A N  GS+    +L +T   +   P I+     + + ++   
Sbjct: 943  LFIRDMQVEDS-GTYVCVAHNEHGSTEASAQLRIT---NLIQPQISATSQEEVVVVEDDV 998

Query: 416  VFPCTAIC-TPEPIIAWYFEGEALIQNH--RRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
            V  C  I   P P + W+   E L   +  R  +  DG+L ++    SD+G YTCVA + 
Sbjct: 999  VVRCNVISGNPPPTVTWFHSSERLYPEYSPRLELFPDGSLGIRGAVMSDAGNYTCVAENA 1058

Query: 473  HG 474
             G
Sbjct: 1059 IG 1060



 Score =  142 bits (344), Expect = 5e-32
 Identities = 127/481 (26%), Positives = 196/481 (40%), Gaps = 37/481 (7%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAG 64
            +T   AP +++ P   T     P TL C A G P P + W K G  L   D    I P+ 
Sbjct: 1612 LTVNLAPILLDSPDSYTSLIRNPVTLQCLAAGFPPPDVTWLKNGAPLNQEDVRYYITPSN 1671

Query: 65   GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
             L         +  D+G+Y C  +N+ G  + ++  L V +          S      + 
Sbjct: 1672 SLLIAST----MREDSGIYTCNVSNTAGH-QYKHMELTVYLPPTSINSGDTSYDVTLNNP 1726

Query: 125  VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
            V L C   +  P P + W K+G+ + +      + +   +L I  A   D+G Y CIA N
Sbjct: 1727 VSLPC-EVQSYPPPTITWLKDGRVIPYTNSH--YRIQPSSLDIPMAVVRDSGVYTCIATN 1783

Query: 185  AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
              G   S    + + + PY+  GP+ + A  G +VT  C   G P P  +W +S    N 
Sbjct: 1784 IVGNI-SRNYQINVQVPPYISPGPDTITAYLGQNVTLPCDSIGVPTPMTMWDKSGLQLNY 1842

Query: 245  PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS-INLSPNSVN 303
               R   LD+GSL + +V   D G Y C   N  GA +    LTV D P  IN  P  + 
Sbjct: 1843 DDSRFHKLDEGSLIISDVRELDAGAYYCLVVNQAGADTRRITLTVKDAPRIINELPEVME 1902

Query: 304  VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
                   R  C ATG P P + W  +G R I       ++     V  G   L I+    
Sbjct: 1903 QIMNTEVRIPCQATGTPRPQVSWFKDG-RPI-------EQLRGYTVL-GDNTLLISSLQP 1953

Query: 364  NDSRNTIVCSAVNYAG----SSFVRGKLT--VTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
             D+     C A + +G      F+  ++   +  ++    P++     +QT+      + 
Sbjct: 1954 YDN-GRYECRAQSESGFDSIDVFIDTQVRPHIAGENTPDDPVVVFTEEDQTV------IL 2006

Query: 418  PCTAICTPEPI-IAWYFEGEALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRH 473
             C    +  P  + WY  G+A++      +   T D +L L  L   D+G Y C A++  
Sbjct: 2007 ECNVTDSHPPAEVTWYQNGQAILARADIGIHFETGDTSLRLPYLRPEDAGHYHCEATNGQ 2066

Query: 474  G 474
            G
Sbjct: 2067 G 2067



 Score =  137 bits (332), Expect = 1e-30
 Identities = 128/487 (26%), Positives = 199/487 (40%), Gaps = 36/487 (7%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFLR 70
            P I +   D+         L C + G P P I WYK G  L +S+ +   L +G L  +R
Sbjct: 2173 PSINDGTSDIVRTLSSSVILPCESAGVPFPEITWYKNGAPLNLSNPNLEKLFSGSL-RIR 2231

Query: 71   ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GDTVVL 127
            +       D+GVY C A N  G     +  +    +     L+P++ ++      + V++
Sbjct: 2232 SVE---EEDSGVYRCVAVNQAG----HDYKMLTLWIHTPPSLQPDASRNVSTGVDEKVII 2284

Query: 128  ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
             C    GSP+P   W KN + LL +   +M L++ G+L+I+D    D G Y C A NA G
Sbjct: 2285 PC-NISGSPKPQYRWLKNNRELLMN-YGKMELLEDGSLMIRDVESIDRGSYTCEATNAVG 2342

Query: 188  TRESAIATLKIHIKPYLITGPEDVVAQTG--SSVTFQCRV-GGDPLPDVLWRRSAGGGNM 244
                 I  L++ + P +      V    G   S+  QC V    P P + W +       
Sbjct: 2343 VLSRDI-RLEVSVAPKITGSKTPVEYPVGQYDSIELQCMVTDAFPPPIIKWYKGDETLTG 2401

Query: 245  PLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
                V + D G +L + +V +A+ GEY C A N  G  S +  + V   PSI    +   
Sbjct: 2402 QEEAVTIKDQGITLEIGSVNIANAGEYYCTATNDAGMASMNWTIDVQVTPSILNGQDEYL 2461

Query: 304  VESGNV-ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
                N+     C A G P PT+ W  +       P   RD ++       + +     TD
Sbjct: 2462 TTVQNIDITLLCEAEGNPTPTITWERDNK-----PLELRDSHYLIGEDGSLRITAPQHTD 2516

Query: 363  KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
                    VC A N  G +     L V     + PP  +      T+ ++      C A 
Sbjct: 2517 SGG----YVCVASNNIGYAIKNFHLVV-----KIPPKTSTQQEVVTIGLRQSVTLRCQAA 2567

Query: 423  CTPEPIIAWYFEGEALIQNHR--RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
              P P I+W  +   +  + R     +N G+L +    + DSG Y+C+AS+  G+     
Sbjct: 2568 GFPAPTISWRKDNLPIPLSTRAFSISSNGGSLTINSTREGDSGIYSCIASNEVGEQSLDI 2627

Query: 481  ALLVDSP 487
             L V  P
Sbjct: 2628 LLKVQEP 2634



 Score =  134 bits (323), Expect = 2e-29
 Identities = 137/487 (28%), Positives = 205/487 (42%), Gaps = 41/487 (8%)

Query: 21   VTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFLRATHGRVHSD 79
            +T  ++   TL C A G+P+P I W +    L + D+H  I   G L   R T  + H+D
Sbjct: 2461 LTTVQNIDITLLCEAEGNPTPTITWERDNKPLELRDSHYLIGEDGSL---RITAPQ-HTD 2516

Query: 80   AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
            +G Y C A+N+ G A  +N  L V  +  +   + E        +V L C    G P P 
Sbjct: 2517 SGGYVCVASNNIGYA-IKNFHL-VVKIPPKTSTQQEVVTIGLRQSVTLRC-QAAGFPAPT 2573

Query: 140  VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
            + W+K+   +     +     +GG+L I   R+ D+G Y CIA N  G  +S    LK+ 
Sbjct: 2574 ISWRKDNLPIPLSTRAFSISSNGGSLTINSTREGDSGIYSCIASNEVG-EQSLDILLKVQ 2632

Query: 200  IKPYL-----ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254
              P +     +   + V    G  +   C   G P P V W R     + P    K+ DD
Sbjct: 2633 EPPIILGELEVNRMQHVQLVEGDDIELPCPTTGYPKPRVAWFRDNRILSPP--EYKIKDD 2690

Query: 255  GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNVESGNVARF 312
            G+L +   +  D G Y+C A N  G  S S  +TV  PP +     P  + V   N AR 
Sbjct: 2691 GTLVIPGAMPFDAGVYTCSAVNEAGNSSISINVTVMVPPLLVDAYRPVDIIVILNNPARL 2750

Query: 313  TCTA-TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371
             C      P  ++ W  +G          R+  +     DG  +L IN    N +     
Sbjct: 2751 YCEIDISIPMASIVWQKDGISL-------REDSNIRISRDG-QILEINQVQVN-NEGRYT 2801

Query: 372  CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG----PSNQTLPIKSMAVFPCTAICTPEP 427
            C A N AG++     LTV       PPI  +G    P   ++         C A   P P
Sbjct: 2802 CIATNNAGNATKFFGLTV-----HVPPIFPDGNPVNPMMMSINEDDSTQLGCHASGYPPP 2856

Query: 428  IIAWYFEGEALIQNHRR-NVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485
             I WY +G  +  N     V+N G  L +  +++  +G +TCVASS  G    S + +++
Sbjct: 2857 TIRWYKDGRLVTHNEPGVAVSNSGEVLRINRVNRIHAGQFTCVASSIVGNI--SKSYVLN 2914

Query: 486  SPINPNI 492
              + P I
Sbjct: 2915 VRVRPEI 2921



 Score =  128 bits (308), Expect = 1e-27
 Identities = 130/478 (27%), Positives = 199/478 (41%), Gaps = 41/478 (8%)

Query: 5    YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG--VLVVSDTHRSILP 62
            Y+   E P I     +VT    Q  TL C A G P P +RW K G  + +V  T R  + 
Sbjct: 702  YLYVQERPQINAYQGNVTFTSSQNITLRCSANGYPHPELRWLKDGQELPIVPGTRRGEI- 760

Query: 63   AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ--SA 120
                  +         D G+Y C A+N   TA S    ++V+   E  R++    +  + 
Sbjct: 761  ------IHQIFNASREDQGIYTCLASN---TAGSDLLNVYVS-YHEPPRIQMTQYRYLTP 810

Query: 121  QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
                  L C P  G P P + W K  + L     +R  +   G+L I   + +D+G Y C
Sbjct: 811  PSQKATLSC-PTSGVPPPEITWFKGDRDLTRVTYTR--IWPNGDLDIMGVQDSDSGSYTC 867

Query: 181  IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
             A N AG   S    L++   P ++  P D+    G +V+  C   G P P V WR+  G
Sbjct: 868  YATNEAGV-VSETVHLEVGSSPIILQPPIDLGVNYGMNVSVTCIAMGHPPPAVTWRK-VG 925

Query: 241  GGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PPSIN- 296
              ++ +  R+ + +DG+L + ++ + D G Y C A N  G+  AS  L + +   P I+ 
Sbjct: 926  QSHLDINPRITMTEDGNLFIRDMQVEDSGTYVCVAHNEHGSTEASAQLRITNLIQPQISA 985

Query: 297  LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
             S   V V   +V       +G P PT+ W     R  ++P  S          DG   L
Sbjct: 986  TSQEEVVVVEDDVVVRCNVISGNPPPTVTWFHSSER--LYPEYSP---RLELFPDG--SL 1038

Query: 357  TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416
             I     +D+ N   C A N  G+     ++ V +     PP I+   ++ T+       
Sbjct: 1039 GIRGAVMSDAGN-YTCVAENAIGNDTKITRIRVHN-----PPSISGTETSYTVIHHESVT 1092

Query: 417  FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
              C A   P P+I W   G+  I N      +   L L  + + D+GTY C  S+  G
Sbjct: 1093 LLCPAAGHPPPLIEWIKNGQT-IPNLG---LHQSALTLSYVTEQDAGTYICRVSNLAG 1146



 Score =  120 bits (290), Expect = 2e-25
 Identities = 88/289 (30%), Positives = 128/289 (44%), Gaps = 20/289 (6%)

Query: 5    YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD----THRSI 60
            Y+T   AP     P DV +A      L C A G P P I W   G  ++ +      RS+
Sbjct: 3369 YLTVQVAPTFTHFPNDVELAAGNRLELICEAIGVPMPDIAWLVNGTEMIPNPPTFDGRSV 3428

Query: 61   LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA 120
            L  G +           SD+G Y C A N  G  R+    + V V     R+ P      
Sbjct: 3429 LAIGNV---------QKSDSGTYMCRAENILG-VRTAITAVRVRVPPRIHRI-PSDTTLT 3477

Query: 121  QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
             G+  VL C    G P+P V W KN + +       M     G+L+I     +DAG Y+C
Sbjct: 3478 LGERAVLNC-AVNGDPKPEVTWLKNNRPVAL--TDTMQQSSDGSLIIAPTAISDAGFYKC 3534

Query: 181  IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
             A N  G  E +   L+I  +P  +  P++     G +V   C   G+P P + W++  G
Sbjct: 3535 QALNLYGLDEVSY-HLEIQSRPMFVVEPQNTTVSHGENVLLDCIAQGEPEPSMRWQKE-G 3592

Query: 241  GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
               +P+GRV +L + +L++    L D G Y C AEN +G    + +LTV
Sbjct: 3593 FRVLPVGRVAILPNNTLKIVAAQLTDSGAYMCLAENQMGRAVMTIHLTV 3641



 Score =  105 bits (251), Expect = 1e-20
 Identities = 95/382 (24%), Positives = 145/382 (37%), Gaps = 28/382 (7%)

Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
           V W + G  L  DG             I+++     G Y CIA N  G+  S    L I 
Sbjct: 558 VRWMRRGTPL--DGPIEFSETGSATWTIKNSDSRIEGVYSCIAENEEGSARSE-TYLDIT 614

Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP-LGRVKVLDDGSLR 258
             P +I  P +     GS     C +      ++ W +     ++    RV ++++GSL 
Sbjct: 615 EPPPVIARPYNTSVLPGSDGVMSCFISSTVEYNITWDKPNTLVSLQGHNRVSLMNNGSLV 674

Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATG 318
           + +V   D G Y C A N  G      YL V + P IN    +V   S       C+A G
Sbjct: 675 IQDVHPGDAGSYRCRAWNEGGVTEEHVYLYVQERPQINAYQGNVTFTSSQNITLRCSANG 734

Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
            P P + W  +G    I PG  R          G  +  I +  + D +    C A N A
Sbjct: 735 YPHPELRWLKDGQELPIVPGTRR----------GEIIHQIFNASRED-QGIYTCLASNTA 783

Query: 379 GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438
           GS  +   ++        PP I         P    A   C     P P I W+     L
Sbjct: 784 GSDLLNVYVSY-----HEPPRIQMTQYRYLTPPSQKATLSCPTSGVPPPEITWFKGDRDL 838

Query: 439 IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY-------VWSGALLVDSPINPN 491
            +     +  +G L +  +  SDSG+YTC A++  G         V S  +++  PI+  
Sbjct: 839 TRVTYTRIWPNGDLDIMGVQDSDSGSYTCYATNEAGVVSETVHLEVGSSPIILQPPIDLG 898

Query: 492 IHFFRAADVSSLP-GPPTKPIT 512
           +++     V+ +  G P   +T
Sbjct: 899 VNYGMNVSVTCIAMGHPPPAVT 920


>UniRef50_P97798 Cluster: Neogenin precursor; n=37;
           Euteleostomi|Rep: Neogenin precursor - Mus musculus
           (Mouse)
          Length = 1493

 Score =  177 bits (432), Expect = 1e-42
 Identities = 192/741 (25%), Positives = 293/741 (39%), Gaps = 86/741 (11%)

Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
           F +EP    S +G +V+L C      P PN+ WKK+G  L  + D R  L+  G+L I +
Sbjct: 66  FLVEPVDTLSVRGSSVILNC-SAYSEPSPNIEWKKDGTFLNLESDDRRQLLPDGSLFISN 124

Query: 170 A-----RQTDAGRYQCIAR-NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223
                  + D G YQC+A  +  GT  S  A L +   P   + PE      G+S    C
Sbjct: 125 VVHSKHNKPDEGFYQCVATVDNLGTIVSRTAKLTVAGLPRFTSQPEPSSVYVGNSAILNC 184

Query: 224 RVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAENS-VG 279
            V  D +P V W ++      PL    R+  L  G+L + N    D G Y C  E+    
Sbjct: 185 EVNADLVPFVRWEQN----RQPLLLDDRIVKLPSGTLVISNATEGDGGLYRCIVESGGPP 240

Query: 280 AVSASGYLTVY-DPPSIN-----LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRT 333
             S    L V  DP  I      + P+S+   +G  A   C  +G P P + W    N  
Sbjct: 241 KFSDEAELKVLQDPEEIVDLVFLMRPSSMMKVTGQSAVLPCVVSGLPAPVVRWMK--NEE 298

Query: 334 IIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
           ++    S        V      L I+D  ++D+  T  C A N   +   + +LTV    
Sbjct: 299 VLDTESS-----GRLVLLAGGCLEISDVTEDDA-GTYFCIADNGNKTVEAQAELTV---- 348

Query: 394 DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLV 453
            + PP     P+N         VF C     P P + W   G+ +I +    +  +  L 
Sbjct: 349 -QVPPGFLKQPANIYAHESMDIVFECEVTGKPTPTVKWVKNGDVVIPSDNFKIVKEHNLQ 407

Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALL-----VDSPINPNIHFFRA-------ADVS 501
           +  L KSD G Y C+A +  G       L+     V  P  P      A       A   
Sbjct: 408 VLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHDVAIPTLPPTSLTSATTDHLAPATTG 467

Query: 502 SLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV 561
            LP  P   +   V+   + L+W           L Y V  +++E +        S+   
Sbjct: 468 PLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSV-FYTKEGVDRERVENTSQPG- 525

Query: 562 VIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVS 621
                  +    +++L+P   Y+F V  +N HG SG S  S  + V         G    
Sbjct: 526 -------EMQVTIQNLMPATVYIFKVMAQNKHG-SGES--SAPLRVETQPEVQLPGP-AP 574

Query: 622 NSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNF--YYLEGLFIYFRPLDNITIEYE 679
           N   Y  +  +   + +   TP+         EI N+  YY+E      +  D    E +
Sbjct: 575 NIRAYATSPTS---ITVTWETPLSGN-----GEIQNYKLYYME------KGTDK---EQD 617

Query: 680 MKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIE 739
           +    HS  ++G     L+KYT+Y F ++ + K   G  +     +TL DVP   P N+ 
Sbjct: 618 IDVSSHSYTING-----LKKYTEYSFRVVAYNKHGPGVSTQDVAVRTLSDVPSAAPQNLS 672

Query: 740 MFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTN 799
           + + N+ ++ + W PP    QNG ITGY +        + KS V          S ++  
Sbjct: 673 LEVRNSKSIVIHWQPPSSTTQNGQITGYKIRYR---KASRKSDVTETLVTGTQLSQLIEG 729

Query: 800 LTSGVSYSVQIAAETIIGLGP 820
           L  G  Y+ ++AA T+ G GP
Sbjct: 730 LDRGTEYNFRVAALTVNGTGP 750



 Score =  160 bits (388), Expect = 2e-37
 Identities = 111/333 (33%), Positives = 148/333 (44%), Gaps = 15/333 (4%)

Query: 13  YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGLFFLR 70
           Y + +P+D    R     LNC A   PSP I W K G  +   SD  R +LP G LF   
Sbjct: 65  YFLVEPVDTLSVRGSSVILNCSAYSEPSPNIEWKKDGTFLNLESDDRRQLLPDGSLFISN 124

Query: 71  ATHGRVHS-DAGVYWCEAT-NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
             H + +  D G Y C AT ++ GT  SR A L VA L   F  +PE      G++ +L 
Sbjct: 125 VVHSKHNKPDEGFYQCVATVDNLGTIVSRTAKLTVAGL-PRFTSQPEPSSVYVGNSAILN 183

Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
           C        P V W++N Q LL D   R+  +  G LVI +A + D G Y+CI  +    
Sbjct: 184 C-EVNADLVPFVRWEQNRQPLLLD--DRIVKLPSGTLVISNATEGDGGLYRCIVESGGPP 240

Query: 189 RESAIATLKIHIKPYLITG------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG- 241
           + S  A LK+   P  I        P  ++  TG S    C V G P P V W ++    
Sbjct: 241 KFSDEAELKVLQDPEEIVDLVFLMRPSSMMKVTGQSAVLPCVVSGLPAPVVRWMKNEEVL 300

Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
                GR+ +L  G L + +V   D G Y C A+N    V A   LTV  PP     P +
Sbjct: 301 DTESSGRLVLLAGGCLEISDVTEDDAGTYFCIADNGNKTVEAQAELTVQVPPGFLKQPAN 360

Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334
           +         F C  TG+P PT+ W   G+  I
Sbjct: 361 IYAHESMDIVFECEVTGKPTPTVKWVKNGDVVI 393



 Score =  139 bits (336), Expect = 5e-31
 Identities = 197/844 (23%), Positives = 325/844 (38%), Gaps = 78/844 (9%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
           +T    P    QP   +V     A LNC       P +RW +    ++ D     LP+G 
Sbjct: 157 LTVAGLPRFTSQPEPSSVYVGNSAILNCEVNADLVPFVRWEQNRQPLLLDDRIVKLPSGT 216

Query: 66  LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-----FRLEPESKQSA 120
           L    AT G    D G+Y C   +      S  A L V    EE     F + P S    
Sbjct: 217 LVISNATEG----DGGLYRCIVESGGPPKFSDEAELKVLQDPEEIVDLVFLMRPSSMMKV 272

Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
            G + VL C+   G P P V W KN + L  +   R+ L+ GG L I D  + DAG Y C
Sbjct: 273 TGQSAVLPCVVS-GLPAPVVRWMKNEEVLDTESSGRLVLLAGGCLEISDVTEDDAGTYFC 331

Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
           IA N   T E A A L + + P  +  P ++ A     + F+C V G P P V W ++ G
Sbjct: 332 IADNGNKTVE-AQAELTVQVPPGFLKQPANIYAHESMDIVFECEVTGKPTPTVKWVKN-G 389

Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV--YDPPSINLS 298
              +P    K++ + +L++  ++ +DEG Y C AEN VG   A   L +  +D     L 
Sbjct: 390 DVVIPSDNFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHDVAIPTLP 449

Query: 299 PNSV-NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF--------PGMSRDKYHATAV 349
           P S+ +  + ++A  T          +  S+   R I          P      Y     
Sbjct: 450 PTSLTSATTDHLAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYT 509

Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF-VRGKLTVTSDDDRPPPIITNGPSNQT 408
            +GV    + +T +       + + +      F V  +    S +   P  +   P  Q 
Sbjct: 510 KEGVDRERVENTSQPGEMQVTIQNLMPATVYIFKVMAQNKHGSGESSAPLRVETQPEVQ- 568

Query: 409 LP-----IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSG 463
           LP     I++ A  P +   T E  ++    G   IQN++      GT   +D+D S S 
Sbjct: 569 LPGPAPNIRAYATSPTSITVTWETPLS----GNGEIQNYKLYYMEKGTDKEQDIDVS-SH 623

Query: 464 TYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAA--DVSSLPGPPTKPITHNVTDT-SV 520
           +YT     ++ +Y  S  ++  +   P +     A   +S +P    + ++  V ++ S+
Sbjct: 624 SYTINGLKKYTEY--SFRVVAYNKHGPGVSTQDVAVRTLSDVPSAAPQNLSLEVRNSKSI 681

Query: 521 TLSWS-QNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIP 579
            + W   ++   +  I GY++  + + +   + T     G         Q   +++ L  
Sbjct: 682 VIHWQPPSSTTQNGQITGYKIR-YRKASRKSDVTETLVTG--------TQLSQLIEGLDR 732

Query: 580 GITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELI 639
           G  Y F V       ++G  P +D ++     + L E       +      L   IV  +
Sbjct: 733 GTEYNFRVAALT---VNGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIV--V 787

Query: 640 EATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSN-DVSGFEITSLR 698
             TP +++ I +        Y  G  I       I ++Y+ +     N D S   + +L+
Sbjct: 788 SWTPPENQNIVVRG------YAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLK 841

Query: 699 KYTKYEFFLIPFYKKFEGKPSNSR-------VAQTLDDVPDG----PPINIEMFILNTTT 747
            +       IP Y+    +P           +      VPD     PP+ ++  IL+  T
Sbjct: 842 AFNNVGEG-IPLYESAVTRPHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSHDT 900

Query: 748 VHLKWSPPELQLQNGIITGYNVVVNW-LDVPANKSMVAINTTVHQATSLIMTNLTSGVSY 806
           + + W+   L     I       V W  ++PAN      N T     S ++T L     Y
Sbjct: 901 IRITWADNSLPKHQKITDSRYYTVRWKTNIPANTKYKNANAT---TLSYLVTGLKPNTLY 957

Query: 807 SVQI 810
              +
Sbjct: 958 EFSV 961



 Score = 82.2 bits (194), Expect = 8e-14
 Identities = 82/317 (25%), Positives = 130/317 (41%), Gaps = 20/317 (6%)

Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
           A  +   R+S  A+++     Y +  P D ++  GSSV   C    +P P++ W++    
Sbjct: 44  ATKSGPRRQSQGASVRTFTPFYFLVEPVDTLSVRGSSVILNCSAYSEPSPNIEWKKDGTF 103

Query: 242 GNMPL-GRVKVLDDGSLRLDNVILA-----DEGEYSCEA--ENSVGAVSASGYLTVYDPP 293
            N+    R ++L DGSL + NV+ +     DEG Y C A  +N    VS +  LTV   P
Sbjct: 104 LNLESDDRRQLLPDGSLFISNVVHSKHNKPDEGFYQCVATVDNLGTIVSRTAKLTVAGLP 163

Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
                P   +V  GN A   C       P + W  E NR    P +  D+     +  G 
Sbjct: 164 RFTSQPEPSSVYVGNSAILNCEVNADLVPFVRW--EQNRQ---PLLLDDR--IVKLPSGT 216

Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIK 412
            V++ N T+ +      +  +      S    +L V  D +    ++    PS+      
Sbjct: 217 LVIS-NATEGDGGLYRCIVESGGPPKFS-DEAELKVLQDPEEIVDLVFLMRPSSMMKVTG 274

Query: 413 SMAVFPCTAICTPEPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470
             AV PC     P P++ W    E L    + R  +   G L + D+ + D+GTY C+A 
Sbjct: 275 QSAVLPCVVSGLPAPVVRWMKNEEVLDTESSGRLVLLAGGCLEISDVTEDDAGTYFCIAD 334

Query: 471 SRHGKYVWSGALLVDSP 487
           + +        L V  P
Sbjct: 335 NGNKTVEAQAELTVQVP 351



 Score = 46.0 bits (104), Expect = 0.006
 Identities = 38/136 (27%), Positives = 57/136 (41%), Gaps = 5/136 (3%)

Query: 694  ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILN--TTTVHLK 751
            +T L+  T YEF ++    +     S +    T + VP  PP ++ +        T+ + 
Sbjct: 948  VTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGATFELVPTSPPKDVTVVSKEGKPRTIIVN 1007

Query: 752  WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811
            W PP     NG ITGY ++    DV A      I   V    +  +  LT    Y  +I 
Sbjct: 1008 WQPPSEA--NGKITGY-IIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQ 1064

Query: 812  AETIIGLGPFSQKVYF 827
            A    G+GP S+ V F
Sbjct: 1065 ARNSKGMGPMSEAVQF 1080


>UniRef50_UPI0000D9D2C3 Cluster: PREDICTED: similar to peroxidasin;
           n=1; Macaca mulatta|Rep: PREDICTED: similar to
           peroxidasin - Macaca mulatta
          Length = 754

 Score =  177 bits (430), Expect = 2e-42
 Identities = 111/351 (31%), Positives = 173/351 (49%), Gaps = 22/351 (6%)

Query: 142 WKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH-- 199
           W      L    DSR++L+D G L+IQ+ ++TD G YQC+A+N AG  ++   TL+    
Sbjct: 365 WGWVSNELSMKTDSRLNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGS 424

Query: 200 -IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---RVKVLDDG 255
             +P  +  P++     G SVT +C   G P P + W R   G   PL    RV +   G
Sbjct: 425 PARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTR---GDRTPLPVDPRVNITPSG 481

Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315
            L + NV+  D GEY+C A NS+ +V A+ ++ V   P   ++P    V  G    F C 
Sbjct: 482 GLYIQNVVQEDSGEYACSATNSIDSVHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCE 541

Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
           A G P P + W+  G++      +S D+ H   V    T L I+    +D +    C AV
Sbjct: 542 AKGNPPPVIAWTKGGSQ------LSVDRRH--LVLSSGT-LRISGVALHD-QGQYECQAV 591

Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG 435
           N  GS  V   LTV     R  P+  + PS+ T+ + +    PC++   PEP I W  +G
Sbjct: 592 NIIGSQKVVAHLTV---QPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDG 648

Query: 436 EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
             + ++ + +++ +G L + D+  +D+G Y CVA +  G    S  L V++
Sbjct: 649 VQVTESGKFHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVLSVNA 699



 Score =  152 bits (369), Expect = 5e-35
 Identities = 105/352 (29%), Positives = 166/352 (47%), Gaps = 24/352 (6%)

Query: 45  WYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV- 103
           W    + + +D+  ++L  G L           +D G+Y C A N  G  +++  TL   
Sbjct: 367 WVSNELSMKTDSRLNLLDDGTLMIQNTQE----TDQGIYQCMAKNVAGEVKTQEVTLRYF 422

Query: 104 -AVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG 162
            +  R  F ++P++ +   G++V LEC    G P P + W +  +T L   D R+++   
Sbjct: 423 GSPARPTFVIQPQNTEVLVGESVTLEC-SATGHPPPRISWTRGDRTPL-PVDPRVNITPS 480

Query: 163 GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQ 222
           G L IQ+  Q D+G Y C A N+  +   A A + +   P     P+D V   G +V FQ
Sbjct: 481 GGLYIQNVVQEDSGEYACSATNSIDS-VHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQ 539

Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGRVK-VLDDGSLRLDNVILADEGEYSCEAENSVGAV 281
           C   G+P P + W +  GG  + + R   VL  G+LR+  V L D+G+Y C+A N +G+ 
Sbjct: 540 CEAKGNPPPVIAWTK--GGSQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQ 597

Query: 282 SASGYLTVYD--PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGM 339
               +LTV     P     P+   VE G   +  C++ G PEP + W+ +G +       
Sbjct: 598 KVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQV-----T 652

Query: 340 SRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTS 391
              K+H +   +G   LTIND    D+     C A N  GS+ V   L+V +
Sbjct: 653 ESGKFHISP--EG--FLTINDVGPADA-GRYECVARNTIGSASVSMVLSVNA 699



 Score =  137 bits (332), Expect = 1e-30
 Identities = 91/288 (31%), Positives = 137/288 (47%), Gaps = 14/288 (4%)

Query: 5   YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPA 63
           Y  S   P  + QP +  V   +  TL C A G P P I W +G    +  D   +I P+
Sbjct: 421 YFGSPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPS 480

Query: 64  GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
           GGL+        V  D+G Y C ATNS  +  +  A + V  L  +F + P+ +   +G 
Sbjct: 481 GGLYIQNV----VQEDSGEYACSATNSIDSVHA-TAFIIVQAL-PQFTVTPQDRVVIEGQ 534

Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIA 182
           TV  +C   +G+P P + W K G  L  D   R HLV   G L I      D G+Y+C A
Sbjct: 535 TVDFQC-EAKGNPPPVIAWTKGGSQLSVD---RRHLVLSSGTLRISGVALHDQGQYECQA 590

Query: 183 RNAAGTRE-SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
            N  G+++  A  T++  + P   + P D   + G++V   C   G+P P + W +  G 
Sbjct: 591 VNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKD-GV 649

Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
                G+  +  +G L +++V  AD G Y C A N++G+ S S  L+V
Sbjct: 650 QVTESGKFHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVLSV 697



 Score = 90.6 bits (215), Expect = 2e-16
 Identities = 64/200 (32%), Positives = 86/200 (43%), Gaps = 16/200 (8%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P     P D  V   Q     C A G+P P I W KGG  +  D    +L +G L   R 
Sbjct: 519 PQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSGTL---RI 575

Query: 72  THGRVHSDAGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEPESKQSAQGDTVVLE 128
           +   +H D G Y C+A N  G   S+    H+ V   +   F   P       G  V L 
Sbjct: 576 SGVALH-DQGQYECQAVNIIG---SQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLP 631

Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
           C   +G PEP + W K+G  +   G  + H+   G L I D    DAGRY+C+ARN  G 
Sbjct: 632 C-SSQGEPEPAITWNKDGVQVTESG--KFHISPEGFLTINDVGPADAGRYECVARNTIG- 687

Query: 189 RESAIATLKIHIKPYLITGP 208
             SA  ++ + +   L   P
Sbjct: 688 --SASVSMVLSVNARLFASP 705



 Score = 79.4 bits (187), Expect = 6e-13
 Identities = 68/247 (27%), Positives = 99/247 (40%), Gaps = 18/247 (7%)

Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY--DP--PSINLSPNSVN 303
           R+ +LDDG+L + N    D+G Y C A+N  G V        Y   P  P+  + P +  
Sbjct: 379 RLNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTE 438

Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
           V  G      C+ATG P P + W+  G+RT + P   R     +    G+ +  +   D 
Sbjct: 439 VLVGESVTLECSATGHPPPRISWT-RGDRTPL-PVDPRVNITPSG---GLYIQNVVQEDS 493

Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
            +      CSA N   S      + V +      P  T  P ++ +       F C A  
Sbjct: 494 GE----YACSATNSIDSVHATAFIIVQA-----LPQFTVTPQDRVVIEGQTVDFQCEAKG 544

Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
            P P+IAW   G  L  + R  V + GTL +  +   D G Y C A +  G       L 
Sbjct: 545 NPPPVIAWTKGGSQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLT 604

Query: 484 VDSPINP 490
           V   + P
Sbjct: 605 VQPRVTP 611


>UniRef50_A7S5L2 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 298

 Score =  175 bits (427), Expect = 5e-42
 Identities = 111/294 (37%), Positives = 157/294 (53%), Gaps = 15/294 (5%)

Query: 6   VTSGE-APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG--VLVVSDTHRSILP 62
           VTS + AP+ +E+P D+ V +++ A L CRAGG PSP I W   G  + +  D  R ILP
Sbjct: 10  VTSSQLAPFFLEEPSDIVVKKNRQALLKCRAGGLPSPRISWRHNGNDLNLAGDKRRKILP 69

Query: 63  AGGLFFLRATHGRVHS-DAGVYWCEATNSYGTA----RSRNATLHVAVLREEFRLEPESK 117
            G L F+   H +    D G Y C A++         RSR   L VA    +F + P S+
Sbjct: 70  DGSLLFITIEHTKSSKPDEGNYQCVASSQVNNLDYEIRSRIVKLQVAG-EADFVVTPPSR 128

Query: 118 QSA-QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAG 176
             A +G   VLEC   +GSP+P V W KNGQ + +D  SR+ ++   NL I     +DAG
Sbjct: 129 VVAIKGKHTVLECAV-KGSPKPVVKWYKNGQIVTYD--SRVTIIGESNLEIMQVVPSDAG 185

Query: 177 RYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
            Y+C A ++     SA   LK++  P  I    D  A TGS VTF C   G+P P+V W 
Sbjct: 186 TYKCEATSSGSQPVSAETRLKVNYPPVFIKRLRDHNAYTGSVVTFNCTADGNPKPNVYW- 244

Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290
            S  G  +       + DG L++++++ +D G Y C A NS+G++ AS  L+VY
Sbjct: 245 -SKNGYKIGSTDFTKVGDGFLKVEDLLPSDMGMYQCFATNSLGSIQASAELSVY 297



 Score =  108 bits (259), Expect = 1e-21
 Identities = 72/243 (29%), Positives = 110/243 (45%), Gaps = 13/243 (5%)

Query: 99  ATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH 158
           +T+  + L   F  EP      +    +L+C    G P P + W+ NG  L   GD R  
Sbjct: 8   STVTSSQLAPFFLEEPSDIVVKKNRQALLKCRAG-GLPSPRISWRHNGNDLNLAGDKRRK 66

Query: 159 LVDGGNLVIQDARQT-----DAGRYQCIARNAAGTRESAIAT--LKIHIK---PYLITGP 208
           ++  G+L+      T     D G YQC+A +     +  I +  +K+ +     +++T P
Sbjct: 67  ILPDGSLLFITIEHTKSSKPDEGNYQCVASSQVNNLDYEIRSRIVKLQVAGEADFVVTPP 126

Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268
             VVA  G     +C V G P P V W ++         RV ++ + +L +  V+ +D G
Sbjct: 127 SRVVAIKGKHTVLECAVKGSPKPVVKWYKNGQIVTYD-SRVTIIGESNLEIMQVVPSDAG 185

Query: 269 EYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327
            Y CEA +S    VSA   L V  PP         N  +G+V  F CTA G P+P ++WS
Sbjct: 186 TYKCEATSSGSQPVSAETRLKVNYPPVFIKRLRDHNAYTGSVVTFNCTADGNPKPNVYWS 245

Query: 328 VEG 330
             G
Sbjct: 246 KNG 248



 Score = 77.4 bits (182), Expect = 2e-12
 Identities = 79/297 (26%), Positives = 116/297 (39%), Gaps = 27/297 (9%)

Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLR 258
           + P+ +  P D+V +       +CR GG P P + WR +    N+    R K+L DGSL 
Sbjct: 15  LAPFFLEEPSDIVVKKNRQALLKCRAGGLPSPRISWRHNGNDLNLAGDKRRKILPDGSLL 74

Query: 259 LDNV-----ILADEGEYSCEAENSVGAV-----SASGYLTVYDPPSINLSPNS-VNVESG 307
              +        DEG Y C A + V  +     S    L V       ++P S V    G
Sbjct: 75  FITIEHTKSSKPDEGNYQCVASSQVNNLDYEIRSRIVKLQVAGEADFVVTPPSRVVAIKG 134

Query: 308 NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
                 C   G P+P + W   G   I+        Y +     G + L I     +D+ 
Sbjct: 135 KHTVLECAVKGSPKPVVKWYKNGQ--IV-------TYDSRVTIIGESNLEIMQVVPSDA- 184

Query: 368 NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427
            T  C A + +GS  V  +  +  +    PP+      +      S+  F CTA   P+P
Sbjct: 185 GTYKCEATS-SGSQPVSAETRLKVNY---PPVFIKRLRDHNAYTGSVVTFNCTADGNPKP 240

Query: 428 IIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
            + W   G  +       V  DG L ++DL  SD G Y C A++  G    S  L V
Sbjct: 241 NVYWSKNGYKIGSTDFTKV-GDGFLKVEDLLPSDMGMYQCFATNSLGSIQASAELSV 296



 Score = 61.3 bits (142), Expect = 2e-07
 Identities = 61/245 (24%), Positives = 102/245 (41%), Gaps = 23/245 (9%)

Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
           P+ + V+    A   C A G P P + W   GN       ++ DK         +  +TI
Sbjct: 23  PSDIVVKKNRQALLKCRAGGLPSPRISWRHNGNDL----NLAGDKRRKILPDGSLLFITI 78

Query: 359 NDT--DKNDSRN--TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
             T   K D  N   +  S VN      +R ++           ++T  P ++ + IK  
Sbjct: 79  EHTKSSKPDEGNYQCVASSQVNNLDYE-IRSRIVKLQVAGEADFVVT--PPSRVVAIKGK 135

Query: 415 -AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
             V  C    +P+P++ WY  G+ +  + R  +  +  L +  +  SD+GTY C A+S  
Sbjct: 136 HTVLECAVKGSPKPVVKWYKNGQIVTYDSRVTIIGESNLEIMQVVPSDAGTYKCEATSSG 195

Query: 474 GKYVWSGALLVDSPIN-PNIHFFRAADVSSLPGPPTKPITHNVT---DTSVTLSWSQNN- 528
            + V +   L    +N P +   R  D ++  G     +T N T   +    + WS+N  
Sbjct: 196 SQPVSAETRL---KVNYPPVFIKRLRDHNAYTG---SVVTFNCTADGNPKPNVYWSKNGY 249

Query: 529 KIGSS 533
           KIGS+
Sbjct: 250 KIGST 254


>UniRef50_UPI0000F2BDAE Cluster: PREDICTED: similar to hCG1996527,;
           n=1; Monodelphis domestica|Rep: PREDICTED: similar to
           hCG1996527, - Monodelphis domestica
          Length = 732

 Score =  174 bits (423), Expect = 1e-41
 Identities = 127/406 (31%), Positives = 186/406 (45%), Gaps = 29/406 (7%)

Query: 8   SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
           +G     +++P DV   R  P  L C+  G P  +I W + G  + + +  +++P G L 
Sbjct: 55  TGSELAFVQEPGDVVALREHPLLLRCQVEGEPPISISWQRDGTPLGNSSGATLMPDGSLH 114

Query: 68  F-----LRATHGRVHSDAGV--YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA 120
                  RA  G +   A V  Y C A N YG   SR A + +A L   F   PES    
Sbjct: 115 LGGFPTHRALQGSLLPPASVHEYNCVAQNRYGRLVSRRARVQLASL-SRFHQHPESMVVE 173

Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
           QG     +CL  RG PEP + W+ N +T L     R  L+  G L I +  Q+D G Y+C
Sbjct: 174 QGGVARFQCL-IRGVPEPTISWEHN-RTALSAAHHRFTLLPAGILQITNVGQSDVGTYRC 231

Query: 181 IARNAAGTRESAIATLKIHIK-------PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233
           +ARN A TR S  A L +  K       P +++GP+++      +   +C   G P P V
Sbjct: 232 VARNVANTRYSQEAQLALSGKDDRALKEPEILSGPQNLTLTVHQTAVLECIATGHPRPLV 291

Query: 234 LWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV--SASGYLTVYD 291
            W R   G ++ +  ++VL  G+L + +V +   G Y C A      V  +A G L V  
Sbjct: 292 SWSR-LDGRSIGVEGIQVLGTGNLMISDVSVQHSGVYVCAANRPGTRVRRTAQGVLLVQA 350

Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
           PP     P SV+   G+ A FTC A G PEP + W   G   ++ PG +    H     +
Sbjct: 351 PPEFVQWPQSVSKPPGSSAIFTCVAQGVPEPRLIWLKNGK--VLSPGENVRLTH-----N 403

Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397
             T++    T  +++     C A N AGS+    +L VT   + PP
Sbjct: 404 NSTLMLAGVTPADEA--IYQCVAENSAGSNQASARLAVTGAPEPPP 447



 Score =  113 bits (271), Expect = 4e-23
 Identities = 134/535 (25%), Positives = 204/535 (38%), Gaps = 57/535 (10%)

Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL------LFDGDSRMHLVDGG 163
           F  EP    + +   ++L C    G P  ++ W+++G  L          D  +HL  GG
Sbjct: 61  FVQEPGDVVALREHPLLLRC-QVEGEPPISISWQRDGTPLGNSSGATLMPDGSLHL--GG 117

Query: 164 ---NLVIQDARQTDAG--RYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSS 218
              +  +Q +    A    Y C+A+N  G   S  A +++         PE +V + G  
Sbjct: 118 FPTHRALQGSLLPPASVHEYNCVAQNRYGRLVSRRARVQLASLSRFHQHPESMVVEQGGV 177

Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSV 278
             FQC + G P P + W  +    +    R  +L  G L++ NV  +D G Y C A N  
Sbjct: 178 ARFQCLIRGVPEPTISWEHNRTALSAAHHRFTLLPAGILQITNVGQSDVGTYRCVARNVA 237

Query: 279 GA-VSASGYLTV-------YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
               S    L +          P I   P ++ +     A   C ATG P P + WS   
Sbjct: 238 NTRYSQEAQLALSGKDDRALKEPEILSGPQNLTLTVHQTAVLECIATGHPRPLVSWSRLD 297

Query: 331 NRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT 390
            R+I   G+            G   L I+D     S    VC+A N  G+   R    V 
Sbjct: 298 GRSIGVEGIQ---------VLGTGNLMISDVSVQHS-GVYVCAA-NRPGTRVRRTAQGVL 346

Query: 391 SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT-ND 449
               + PP     P + + P  S A+F C A   PEP + W   G+ L       +T N+
Sbjct: 347 L--VQAPPEFVQWPQSVSKPPGSSAIFTCVAQGVPEPRLIWLKNGKVLSPGENVRLTHNN 404

Query: 450 GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTK 509
            TL+L  +  +D   Y CVA +  G    S  L V     P             P  P  
Sbjct: 405 STLMLAGVTPADEAIYQCVAENSAGSNQASARLAVTGAPEP-------------PPAPQG 451

Query: 510 PITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQ 569
                ++ ++V +SW         SI+GY +       L     P        +++   +
Sbjct: 452 LQAAALSASAVRVSWEPPPARDKPSIIGYVL------LLQPEGEPPGREVQEAVSKGTFE 505

Query: 570 THYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNST 624
             +V  +L P  TY   +R  ++ G S  SP     T+G+   +L   T V N+T
Sbjct: 506 --HVFTNLDPATTYSVRLRAYSAEGASHDSPPVHITTMGNAPAALGFSTKVLNAT 558


>UniRef50_UPI0000DA21B5 Cluster: PREDICTED: similar to hemicentin 1;
            n=1; Rattus norvegicus|Rep: PREDICTED: similar to
            hemicentin 1 - Rattus norvegicus
          Length = 2765

 Score =  170 bits (414), Expect = 2e-40
 Identities = 139/481 (28%), Positives = 215/481 (44%), Gaps = 37/481 (7%)

Query: 16   EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFFLRATHG 74
            + PL VTV   + ATL+C A GSP+P + W K    ++  T+R  +L +G L  ++   G
Sbjct: 889  DAPLRVTVKAGEEATLDCEAQGSPTPLVTWTKDAHPLLPVTNRYELLSSGSLRLVQTQVG 948

Query: 75   RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRG 134
                D+G+Y C A+N  G A  R   L V V   + +  P   +   G+ + L C+   G
Sbjct: 949  ----DSGLYECTASNPAG-ATFRRYILGVQV-PPQVQPGPRVLKVLAGEALDLNCVA-EG 1001

Query: 135  SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194
            +P+P + W K+G  L+ +G         G++     + +D G Y C A +++GT    + 
Sbjct: 1002 NPQPQLNWFKDGMVLMGEGPP-------GSVHFAAVKTSDTGLYHCEASSSSGTDTWKLE 1054

Query: 195  TLKIHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR--VKV 251
               +    + +    D++ +  G + +  C   G P P + WRR      +  GR  V V
Sbjct: 1055 LQVLEPPHWGVNETNDLLERVVGENASLLCPAQGSPKPRITWRRVPSSEALN-GRPDVAV 1113

Query: 252  LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE--SGNV 309
            L++GSL L +V LAD GEY C+A N VG+ S    L VY PPSI     + N+   +G  
Sbjct: 1114 LNEGSLFLSSVSLADSGEYECQATNEVGSASRRVKLVVYVPPSIREEGRTANMSGLAGQP 1173

Query: 310  ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
                C A+G P P + W  +G +    P  S  ++      DG   L      +N S   
Sbjct: 1174 LTLECDASGFPVPEVVWLKDGQQ---IPEASAHRF-----LDGARSLHFPRIQENHS-GL 1224

Query: 370  IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPI 428
              C A N AG +     L V      PP ++  G + + L +    V   C     P P 
Sbjct: 1225 YSCQAENQAGRAQRDFNLAVFI----PPSLLGAGAAQEVLGLAGADVKLECQTSGVPTPQ 1280

Query: 429  IAWYFEGEALIQNHRRNVTNDGTLVLKDLDK--SDSGTYTCVASSRHGKYVWSGALLVDS 486
            + W  +G+ L+      +  +   VL+ +     D G Y CVA S  G+      L + S
Sbjct: 1281 VEWIKDGQPLLPGDSHILLQEDGQVLRIISSHLGDEGRYQCVAFSPAGQQAKDFQLSIHS 1340

Query: 487  P 487
            P
Sbjct: 1341 P 1341



 Score =  161 bits (390), Expect = 1e-37
 Identities = 146/514 (28%), Positives = 206/514 (40%), Gaps = 44/514 (8%)

Query: 9    GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL---PAGG 65
            G AP + + P DVTV   +   L CRA G P P + W +G    +    RS      +G 
Sbjct: 689  GYAPRLTDPPQDVTVELGKSVFLTCRATGRPPPTVTWRRGDGQALEPGRRSRTGQRDSGV 748

Query: 66   LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
            L F R +      D   Y CEA N +G A++    +       +        +  +G  V
Sbjct: 749  LVFERVSL----EDQAPYVCEARNVFGKAQAEAQLVVTGHAPPQIASSASVVRVLEGQPV 804

Query: 126  VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
             L C+   G P P   W K G+ L   G+      DG +L +  A Q DAGRY C+A N 
Sbjct: 805  SLTCVILAGRPLPERRWLKAGRPLP-PGNRHAVRADG-SLHLDRALQEDAGRYSCVATNV 862

Query: 186  AGTRESAIATLKIHIKPYL-------ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238
            AG++   +  L +  KP +          P  V  + G   T  C   G P P V W + 
Sbjct: 863  AGSQHRDVE-LVVQAKPRIKINDSQATDAPLRVTVKAGEEATLDCEAQGSPTPLVTWTKD 921

Query: 239  AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
            A        R ++L  GSLRL    + D G Y C A N  GA      L V  PP +   
Sbjct: 922  AHPLLPVTNRYELLSSGSLRLVQTQVGDSGLYECTASNPAGATFRRYILGVQVPPQVQPG 981

Query: 299  PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
            P  + V +G      C A G P+P + W  +G   ++         H  AV         
Sbjct: 982  PRVLKVLAGEALDLNCVAEGNPQPQLNWFKDG--MVLMGEGPPGSVHFAAV--------- 1030

Query: 359  NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP--IKSMAV 416
                K        C A + +G+   + +L V       PP      +N  L   +   A 
Sbjct: 1031 ----KTSDTGLYHCEASSSSGTDTWKLELQVLE-----PPHWGVNETNDLLERVVGENAS 1081

Query: 417  FPCTAICTPEPIIAWYFEGEALIQNHRRNVT--NDGTLVLKDLDKSDSGTYTCVASSRHG 474
              C A  +P+P I W     +   N R +V   N+G+L L  +  +DSG Y C A++  G
Sbjct: 1082 LLCPAQGSPKPRITWRRVPSSEALNGRPDVAVLNEGSLFLSSVSLADSGEYECQATNEVG 1141

Query: 475  KYVWSGALLVDSPINPNI-HFFRAADVSSLPGPP 507
                   L+V  P  P+I    R A++S L G P
Sbjct: 1142 SASRRVKLVVYVP--PSIREEGRTANMSGLAGQP 1173



 Score =  156 bits (379), Expect = 3e-36
 Identities = 145/500 (29%), Positives = 209/500 (41%), Gaps = 26/500 (5%)

Query: 2   SDDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL 61
           S   V +   P ++  P +VTV+  + A L+C+  G     + W +    +   T R + 
Sbjct: 414 SAQIVITDPPPQLVPGP-NVTVSPGETAILSCQVLGETPYNLTWVRDWRALPVKTGR-VS 471

Query: 62  PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEPESKQS 119
               L         V SD G Y C A+N  G  R+    L    +RE  +  +   S++ 
Sbjct: 472 QLRDLSL--EVSSVVPSDGGQYQCVASNPNGLTRASTWLL----VREPPQVSINARSQRF 525

Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179
           +QG  V + C    G P+P+V W + G  L    DSR+H+   G L+IQ     DAG Y 
Sbjct: 526 SQGVEVRVSC-SASGYPKPHVSWSREG--LALPEDSRIHVDAQGTLIIQGVAPEDAGNYS 582

Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
           C A N  GT E  + TL     P +      V+   G      C   G P P V+W R  
Sbjct: 583 CQAANEVGTDEETV-TLYYTDPPSVSAINAVVLTAVGEEAVLLCAASGVPPPRVIWYR-- 639

Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
            GG   +   +    G+LR+      D G Y+C+A N +G  SA   L V   P +   P
Sbjct: 640 -GGLEVILAPEGSRSGTLRIPEAQERDAGLYTCKAVNELGDASAEIQLLVGYAPRLTDPP 698

Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
             V VE G     TC ATGRP PT+ W   G+   + PG    +   T   D   VL   
Sbjct: 699 QDVTVELGKSVFLTCRATGRPPPTVTWR-RGDGQALEPG----RRSRTGQRDS-GVLVFE 752

Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419
                D +   VC A N  G +    +L VT     PP I ++    + L  + +++   
Sbjct: 753 RVSLED-QAPYVCEARNVFGKAQAEAQLVVTG--HAPPQIASSASVVRVLEGQPVSLTCV 809

Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479
                P P   W   G  L   +R  V  DG+L L    + D+G Y+CVA++  G     
Sbjct: 810 ILAGRPLPERRWLKAGRPLPPGNRHAVRADGSLHLDRALQEDAGRYSCVATNVAGSQHRD 869

Query: 480 GALLVDSPINPNIHFFRAAD 499
             L+V +     I+  +A D
Sbjct: 870 VELVVQAKPRIKINDSQATD 889



 Score =  155 bits (377), Expect = 5e-36
 Identities = 139/457 (30%), Positives = 185/457 (40%), Gaps = 40/457 (8%)

Query: 31  LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
           ++C A G P P + W + G+ +  D+   +   G L       G    DAG Y C+A N 
Sbjct: 533 VSCSASGYPKPHVSWSREGLALPEDSRIHVDAQGTLII----QGVAPEDAGNYSCQAANE 588

Query: 91  YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG-QTL 149
            GT      TL+         +      +A G+  VL C    G P P V W + G + +
Sbjct: 589 VGTDEE-TVTLYYTDPPSVSAINAVVL-TAVGEEAVLLCAAS-GVPPPRVIWYRGGLEVI 645

Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
           L    SR      G L I +A++ DAG Y C A N  G   + I  L +   P L   P+
Sbjct: 646 LAPEGSR-----SGTLRIPEAQERDAGLYTCKAVNELGDASAEIQLL-VGYAPRLTDPPQ 699

Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDGSLRLDNVILADE 267
           DV  + G SV   CR  G P P V WRR  G    P  R +    D G L  + V L D+
Sbjct: 700 DVTVELGKSVFLTCRATGRPPPTVTWRRGDGQALEPGRRSRTGQRDSGVLVFERVSLEDQ 759

Query: 268 GEYSCEAENSVGAVSASGYLTV--YDPPSINLSPNSVNVESGNVARFTCTA-TGRPEPTM 324
             Y CEA N  G   A   L V  + PP I  S + V V  G     TC    GRP P  
Sbjct: 760 APYVCEARNVFGKAQAEAQLVVTGHAPPQIASSASVVRVLEGQPVSLTCVILAGRPLPER 819

Query: 325 FWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF-- 382
            W   G    + PG      HA    DG   L   D    +      C A N AGS    
Sbjct: 820 RWLKAGRP--LPPG----NRHAVRA-DGSLHL---DRALQEDAGRYSCVATNVAGSQHRD 869

Query: 383 ----VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438
               V+ K  +  +D +     T+ P   T+     A   C A  +P P++ W  +   L
Sbjct: 870 VELVVQAKPRIKINDSQA----TDAPLRVTVKAGEEATLDCEAQGSPTPLVTWTKDAHPL 925

Query: 439 IQ-NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
           +   +R  + + G+L L      DSG Y C AS+  G
Sbjct: 926 LPVTNRYELLSSGSLRLVQTQVGDSGLYECTASNPAG 962



 Score =  142 bits (343), Expect = 7e-32
 Identities = 127/474 (26%), Positives = 204/474 (43%), Gaps = 39/474 (8%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P +   P  + V   +   LNC A G+P P + W+K G++++ +      P G + F   
Sbjct: 976  PQVQPGPRVLKVLAGEALDLNCVAEGNPQPQLNWFKDGMVLMGEG-----PPGSVHFAAV 1030

Query: 72   THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK---QSAQGDTVVLE 128
                  SD G+Y CEA++S GT   +   L + VL        E+    +   G+   L 
Sbjct: 1031 K----TSDTGLYHCEASSSSGTDTWK---LELQVLEPPHWGVNETNDLLERVVGENASLL 1083

Query: 129  CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
            C P +GSP+P + W++   +   +G   + +++ G+L +      D+G Y+C A N  G+
Sbjct: 1084 C-PAQGSPKPRITWRRVPSSEALNGRPDVAVLNEGSLFLSSVSLADSGEYECQATNEVGS 1142

Query: 189  RESAIATLKIHIKPYLIT--GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
                +  L +++ P +       ++    G  +T +C   G P+P+V+W +   G  +P 
Sbjct: 1143 ASRRV-KLVVYVPPSIREEGRTANMSGLAGQPLTLECDASGFPVPEVVWLKD--GQQIPE 1199

Query: 247  GRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
                   DG  SL    +     G YSC+AEN  G       L V+ PPS+  +  +  V
Sbjct: 1200 ASAHRFLDGARSLHFPRIQENHSGLYSCQAENQAGRAQRDFNLAVFIPPSLLGAGAAQEV 1259

Query: 305  --ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
               +G   +  C  +G P P + W  +G    + PG S    H     DG  VL I  + 
Sbjct: 1260 LGLAGADVKLECQTSGVPTPQVEWIKDGQP--LLPGDS----HILLQEDG-QVLRIISSH 1312

Query: 363  KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS-MAVFPCTA 421
              D      C A + AG      +L++ S    PP I  +  + +   ++   A   C A
Sbjct: 1313 LGD-EGRYQCVAFSPAGQQAKDFQLSIHS----PPTIWGSNETGEVTVLEGHTAQLLCEA 1367

Query: 422  ICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
               P P I WY +G  L  +     +  G  L L     SD+G YTC AS+  G
Sbjct: 1368 RGMPAPDITWYKDGTLLAPSSEVIYSKGGRQLQLGKAQHSDAGLYTCQASNSAG 1421



 Score =  122 bits (295), Expect = 5e-26
 Identities = 94/308 (30%), Positives = 138/308 (44%), Gaps = 18/308 (5%)

Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVG 226
           I  A + + G YQCIA + AGT  ++   +     P L+ GP +V    G +    C+V 
Sbjct: 389 IPRASKAEEGVYQCIAVSRAGTGRASAQIVITDPPPQLVPGP-NVTVSPGETAILSCQVL 447

Query: 227 GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY 286
           G+   ++ W R      +  GRV  L D SL + +V+ +D G+Y C A N  G   AS +
Sbjct: 448 GETPYNLTWVRDWRALPVKTGRVSQLRDLSLEVSSVVPSDGGQYQCVASNPNGLTRASTW 507

Query: 287 LTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHA 346
           L V +PP ++++  S     G   R +C+A+G P+P + WS EG   +  P  SR   H 
Sbjct: 508 LLVREPPQVSINARSQRFSQGVEVRVSCSASGYPKPHVSWSREG---LALPEDSR--IHV 562

Query: 347 TAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN 406
               D    L I      D+ N   C A N  G+     + TVT     PP +       
Sbjct: 563 ----DAQGTLIIQGVAPEDAGN-YSCQAANEVGTD----EETVTLYYTDPPSVSAINAVV 613

Query: 407 QTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYT 466
            T  +   AV  C A   P P + WY  G  +I       +  GTL + +  + D+G YT
Sbjct: 614 LT-AVGEEAVLLCAASGVPPPRVIWYRGGLEVIL--APEGSRSGTLRIPEAQERDAGLYT 670

Query: 467 CVASSRHG 474
           C A +  G
Sbjct: 671 CKAVNELG 678



 Score =  121 bits (292), Expect = 1e-25
 Identities = 117/435 (26%), Positives = 171/435 (39%), Gaps = 31/435 (7%)

Query: 78  SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS-AQGDTVVLECLPPRGSP 136
           ++ GVY C A +  GT R   A+  + +     +L P    + + G+T +L C    G  
Sbjct: 395 AEEGVYQCIAVSRAGTGR---ASAQIVITDPPPQLVPGPNVTVSPGETAILSC-QVLGET 450

Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
             N+ W ++ + L      R+  +   +L +     +D G+YQC+A N  G    A   L
Sbjct: 451 PYNLTWVRDWRALPVK-TGRVSQLRDLSLEVSSVVPSDGGQYQCVASNPNGLTR-ASTWL 508

Query: 197 KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDG 255
            +   P +           G  V   C   G P P V W R   G  +P   R+ V   G
Sbjct: 509 LVREPPQVSINARSQRFSQGVEVRVSCSASGYPKPHVSWSRE--GLALPEDSRIHVDAQG 566

Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315
           +L +  V   D G YSC+A N VG    +  L   DPPS++     V    G  A   C 
Sbjct: 567 TLIIQGVAPEDAGNYSCQAANEVGTDEETVTLYYTDPPSVSAINAVVLTAVGEEAVLLCA 626

Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
           A+G P P + W   G   I+ P  SR              L I +  + D+     C AV
Sbjct: 627 ASGVPPPRVIWYRGGLEVILAPEGSRS-----------GTLRIPEAQERDA-GLYTCKAV 674

Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-YFE 434
           N  G +    +L V        P +T+ P + T+ +       C A   P P + W   +
Sbjct: 675 NELGDASAEIQLLVGY-----APRLTDPPQDVTVELGKSVFLTCRATGRPPPTVTWRRGD 729

Query: 435 GEALIQNHRRNV--TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
           G+AL    R      + G LV + +   D   Y C A +  GK      L+V     P I
Sbjct: 730 GQALEPGRRSRTGQRDSGVLVFERVSLEDQAPYVCEARNVFGKAQAEAQLVVTGHAPPQI 789

Query: 493 HFFRAADVSSLPGPP 507
               A+ V  L G P
Sbjct: 790 -ASSASVVRVLEGQP 803



 Score =  110 bits (264), Expect = 3e-22
 Identities = 97/301 (32%), Positives = 132/301 (43%), Gaps = 21/301 (6%)

Query: 27   QPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85
            QP TL C A G P P + W K G  +  +  HR +  A  L F R      HS  G+Y C
Sbjct: 1172 QPLTLECDASGFPVPEVVWLKDGQQIPEASAHRFLDGARSLHFPRIQEN--HS--GLYSC 1227

Query: 86   EATNSYGTARSRNATLHVAVLREEFRLEPESKQSA---QGDTVVLECLPPRGSPEPNVYW 142
            +A N  G A+      ++AV      L   + Q      G  V LEC    G P P V W
Sbjct: 1228 QAENQAGRAQR---DFNLAVFIPPSLLGAGAAQEVLGLAGADVKLEC-QTSGVPTPQVEW 1283

Query: 143  KKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201
             K+GQ LL  GDS + L + G ++ I  +   D GRYQC+A + AG +++    L IH  
Sbjct: 1284 IKDGQPLL-PGDSHILLQEDGQVLRIISSHLGDEGRYQCVAFSPAG-QQAKDFQLSIHSP 1341

Query: 202  PYLITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG-SLR 258
            P +    E  +V    G +    C   G P PD+ W +  G    P   V     G  L+
Sbjct: 1342 PTIWGSNETGEVTVLEGHTAQLLCEARGMPAPDITWYKD-GTLLAPSSEVIYSKGGRQLQ 1400

Query: 259  LDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PPSINLSPNSVNVESGNVARFTCTA 316
            L     +D G Y+C+A NS G    S  L VY   P   +        +  +   +TC+A
Sbjct: 1401 LGKAQHSDAGLYTCQASNSAGITKKSTNLEVYGERPEGCSSGQLIEKADLRDEGVYTCSA 1460

Query: 317  T 317
            T
Sbjct: 1461 T 1461



 Score =  106 bits (255), Expect = 3e-21
 Identities = 81/285 (28%), Positives = 118/285 (41%), Gaps = 20/285 (7%)

Query: 166  VIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV 225
            +I+ A   D G Y C A N AG  +  + TLK+ + P +  GP +      +SVT +C  
Sbjct: 1444 LIEKADLRDEGVYTCSATNLAGESKKDV-TLKVLVPPNIEPGPVNKAVLENASVTLECLA 1502

Query: 226  GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASG 285
             G P PD+ W +     +     +   D   L ++   L+D G Y C A N VG+ +   
Sbjct: 1503 SGVPPPDISWFKGRQPISTQRHLIVSTDGRVLHIERAQLSDAGSYRCVATNVVGSAALQY 1562

Query: 286  YLTVYDPPSINLSPNSVN-VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
             L V  PP I L P+    V  G   R TC ATG P P + W  +GN       +S +  
Sbjct: 1563 GLRVNVPPRITLPPSLPGPVVLGTPFRLTCNATGTPSPMLLWLKDGN------PVSPEGT 1616

Query: 345  HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD----------- 393
                VF G  VLT+     +D+     C AV+  G       L V S+            
Sbjct: 1617 PGLKVFPGGQVLTVASARASDA-GGYSCVAVSAVGEDRRDIVLQVHSESLAWDGVCGVSI 1675

Query: 394  DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438
             + PP I     N ++ +       C +   P P++ W  +G  L
Sbjct: 1676 AKVPPSILGEELNISVVVNESVALECRSHAVPPPVLRWQKDGRPL 1720



 Score = 87.0 bits (206), Expect = 3e-15
 Identities = 83/290 (28%), Positives = 124/290 (42%), Gaps = 34/290 (11%)

Query: 79   DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
            D GVY C ATN  G ++ ++ TL V V        P +K   +  +V LECL   G P P
Sbjct: 1452 DEGVYTCSATNLAGESK-KDVTLKVLV-PPNIEPGPVNKAVLENASVTLECL-ASGVPPP 1508

Query: 139  NVYWKKNGQTLLFDGDSRMHLV---DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195
            ++ W K  Q +     ++ HL+   DG  L I+ A+ +DAG Y+C+A N  G+       
Sbjct: 1509 DISWFKGRQPI----STQRHLIVSTDGRVLHIERAQLSDAGSYRCVATNVVGSAALQYG- 1563

Query: 196  LKIHIKPYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR--VKVL 252
            L++++ P +   P        G+     C   G P P +LW +  G    P G   +KV 
Sbjct: 1564 LRVNVPPRITLPPSLPGPVVLGTPFRLTCNATGTPSPMLLWLKD-GNPVSPEGTPGLKVF 1622

Query: 253  DDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD----------------PPSI 295
              G  L + +   +D G YSC A ++VG       L V+                 PPSI
Sbjct: 1623 PGGQVLTVASARASDAGGYSCVAVSAVGEDRRDIVLQVHSESLAWDGVCGVSIAKVPPSI 1682

Query: 296  NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPG--MSRDK 343
                 +++V         C +   P P + W  +G      PG  +S DK
Sbjct: 1683 LGEELNISVVVNESVALECRSHAVPPPVLRWQKDGRPLEPHPGIRLSADK 1732



 Score = 87.0 bits (206), Expect = 3e-15
 Identities = 112/431 (25%), Positives = 163/431 (37%), Gaps = 51/431 (11%)

Query: 55   DTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL-E 113
            D+   +L  G L +L        +  G Y CE +N  GT+ S+   L V V  +   L E
Sbjct: 1798 DSQEQVLAVGRLLYLGQAQS---AQEGTYTCECSNVAGTS-SQEQQLEVLVPPQVTGLWE 1853

Query: 114  PESKQSA-QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ 172
            P +  S  Q     L+C    G P P V W+++GQ +  +    +      +L +  A+ 
Sbjct: 1854 PLTTVSVIQDGNATLDC-NATGKPLPVVTWERDGQPVRMELGIWLQN-QNHSLHVDRAQA 1911

Query: 173  TDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED----VVAQTGSSVTFQCRVGGD 228
            + AG Y C+A N AG  E   A L +   P+L TG  D    V A    S+T  C   G 
Sbjct: 1912 SHAGGYSCVAENIAGRAERRFA-LSVLAPPHL-TGDSDSLTNVTATLHGSLTLLCEAEGI 1969

Query: 229  PLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
            P P V W R   G  +  G    L         +  AD G      E       A G +T
Sbjct: 1970 PPPTVQWFRE--GQPISPGEGTYLLAVPPMFQKMGDADAGFELLPHEEE-----AQGRVT 2022

Query: 289  VYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
             Y             V   N A   C     P P + W  EG       G+S        
Sbjct: 2023 EYR-----------EVVENNPAYLYCDTNAIPPPELTWYREGQPLSAVDGVS-------- 2063

Query: 349  VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ- 407
            V  G  +L +      D+     C A N  G  ++  +L V +     PP+I        
Sbjct: 2064 VLQGGRILQLPLVQAEDA-GRYSCKASNEVGEDWLHYELLVLT-----PPVIPGDTQELV 2117

Query: 408  ---TLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSG 463
               T+   S     C A+  P P ++W+  G  +  + R  V  +G  L +   + +D+ 
Sbjct: 2118 EEVTVNASSAVSLECPALGNPAPALSWFQNGLPVSPSPRLQVLEEGQVLKVSTAEVTDAA 2177

Query: 464  TYTCVASSRHG 474
             Y CVA ++ G
Sbjct: 2178 NYMCVAENQAG 2188



 Score = 80.2 bits (189), Expect = 3e-13
 Identities = 66/194 (34%), Positives = 88/194 (45%), Gaps = 12/194 (6%)

Query: 146  GQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL 204
            GQ L  DGDS+  ++  G L+ +  A+    G Y C   N AGT  S    L++ + P  
Sbjct: 1790 GQPLPGDGDSQEQVLAVGRLLYLGQAQSAQEGTYTCECSNVAGT-SSQEQQLEVLVPPQ- 1847

Query: 205  ITG---PEDVVA--QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL 259
            +TG   P   V+  Q G++ T  C   G PLP V W R      M LG      + SL +
Sbjct: 1848 VTGLWEPLTTVSVIQDGNA-TLDCNATGKPLPVVTWERDGQPVRMELGIWLQNQNHSLHV 1906

Query: 260  DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV-NVESGNVARFT--CTA 316
            D    +  G YSC AEN  G       L+V  PP +    +S+ NV +      T  C A
Sbjct: 1907 DRAQASHAGGYSCVAENIAGRAERRFALSVLAPPHLTGDSDSLTNVTATLHGSLTLLCEA 1966

Query: 317  TGRPEPTMFWSVEG 330
             G P PT+ W  EG
Sbjct: 1967 EGIPPPTVQWFREG 1980



 Score = 80.2 bits (189), Expect = 3e-13
 Identities = 61/213 (28%), Positives = 100/213 (46%), Gaps = 17/213 (7%)

Query: 121  QGDTVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179
            +G  V L C    G P P++ W K G  L    G      +DG  LV++  R  D+G Y 
Sbjct: 2397 EGQEVRLGC-EAEGQPPPDIAWLKEGGPLDQHVGPHLRFYLDGSTLVLKGLRAADSGAYT 2455

Query: 180  CIARNAAGTRESAIATLKIHIKPYLITGPED---VVAQTGSSVTFQCRVGGDPLPDVLWR 236
            C+A N AG  ++ + T+ + + P +     D   +V++TG  VT  C V G P   V W 
Sbjct: 2456 CVAHNPAG-EDARLHTVNVLVPPTIKQQASDTGTLVSRTGELVTMMCPVQGSPPIHVSWL 2514

Query: 237  RSAGGGNMPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV----- 289
            +   G  + L +  +L +   +LR+  V LAD G ++C A +  G  + +  L V     
Sbjct: 2515 KD--GLPLALSQRTLLHNSGRTLRISQVQLADSGVFTCVASSPAGVANRNFTLLVDKGSV 2572

Query: 290  -YDPPSINLSPNSVNVESGNVARFTCTATGRPE 321
              D PS+ + P ++++ + + A+        PE
Sbjct: 2573 LEDSPSVRV-PKALSMRATDCAKIQVPPILEPE 2604



 Score = 78.2 bits (184), Expect = 1e-12
 Identities = 88/320 (27%), Positives = 124/320 (38%), Gaps = 44/320 (13%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P I   P++  V  +   TL C A G P P I W+KG   + +  H  +   G +  +  
Sbjct: 1479 PNIEPGPVNKAVLENASVTLECLASGVPPPDISWFKGRQPISTQRHLIVSTDGRVLHIER 1538

Query: 72   THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
                  SDAG Y C ATN  G+A  +   L V V      L P         T       
Sbjct: 1539 AQ---LSDAGSYRCVATNVVGSAALQYG-LRVNV-PPRITLPPSLPGPVVLGTPFRLTCN 1593

Query: 132  PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRE 190
              G+P P + W K+G  +  +G   + +  GG  L +  AR +DAG Y C+A +A G   
Sbjct: 1594 ATGTPSPMLLWLKDGNPVSPEGTPGLKVFPGGQVLTVASARASDAGGYSCVAVSAVGEDR 1653

Query: 191  SAIATLKIHIK---------------PYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVL 234
              I  L++H +               P  I G E ++      SV  +CR    P P + 
Sbjct: 1654 RDI-VLQVHSESLAWDGVCGVSIAKVPPSILGEELNISVVVNESVALECRSHAVPPPVLR 1712

Query: 235  W-------------RRSAGGGNMPLGRV------KVLDDG--SLRLDNVILADEGEYSCE 273
            W             R SA    + + R       K  + G   L +D V + D G Y+CE
Sbjct: 1713 WQKDGRPLEPHPGIRLSADKALLEVCRCAARCPEKPNEQGRVDLWVDRVAVWDAGHYTCE 1772

Query: 274  AENSVGAVSASGYLTVYDPP 293
            A N  G       L V+  P
Sbjct: 1773 AINQAGRSEKHFNLHVWGQP 1792



 Score = 77.0 bits (181), Expect = 3e-12
 Identities = 77/313 (24%), Positives = 130/313 (41%), Gaps = 25/313 (7%)

Query: 216  GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGS-LRLDNVILADEGEYSCE 273
            G  V   C   G P PD+ W +  G  +  +G  ++   DGS L L  +  AD G Y+C 
Sbjct: 2398 GQEVRLGCEAEGQPPPDIAWLKEGGPLDQHVGPHLRFYLDGSTLVLKGLRAADSGAYTCV 2457

Query: 274  AENSVGAVSASGYLTVYDPPSINLSPNSVNV---ESGNVARFTCTATGRPEPTMFWSVEG 330
            A N  G  +    + V  PP+I    +        +G +    C   G P   + W  +G
Sbjct: 2458 AHNPAGEDARLHTVNVLVPPTIKQQASDTGTLVSRTGELVTMMCPVQGSPPIHVSWLKDG 2517

Query: 331  ------NRTIIFPG-----MSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379
                   RT++        +S+ +   + VF  V        ++N +      S +  + 
Sbjct: 2518 LPLALSQRTLLHNSGRTLRISQVQLADSGVFTCVASSPAGVANRNFTLLVDKGSVLEDSP 2577

Query: 380  SSFVRGKLTVTSDDD---RPPPIITNGP-SNQTLPIK-SMAVFPCTAICTPEPIIAWYFE 434
            S  V   L++ + D    + PPI+      N  +  + S  V PC A  +P P+++W  +
Sbjct: 2578 SVRVPKALSMRATDCAKIQVPPILEPEEFQNDVMAAQGSEVVLPCEARGSPLPLVSWMKD 2637

Query: 435  GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV-DSPINPNIH 493
            GE L+    +++     L L+ +   DSGTY+C+A+S  G+      L V +  + P  H
Sbjct: 2638 GEPLLP---QSLEQGPGLKLEAVSIGDSGTYSCMAASEAGEARRHFQLTVMELSLTPGAH 2694

Query: 494  FFRAADVSSLPGP 506
                 +   +P P
Sbjct: 2695 LELLCEARGIPPP 2707



 Score = 69.3 bits (162), Expect = 6e-10
 Identities = 52/179 (29%), Positives = 79/179 (44%), Gaps = 10/179 (5%)

Query: 23   VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
            V  + PA L C     P P + WY+ G  + +    S+L  G +  L         DAG 
Sbjct: 2027 VVENNPAYLYCDTNAIPPPELTWYREGQPLSAVDGVSVLQGGRILQLPLVQAE---DAGR 2083

Query: 83   YWCEATNSYGT--ARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
            Y C+A+N  G          L   V+  + +   E         V LEC P  G+P P +
Sbjct: 2084 YSCKASNEVGEDWLHYELLVLTPPVIPGDTQELVEEVTVNASSAVSLEC-PALGNPAPAL 2142

Query: 141  YWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
             W +NG  L      R+ +++ G ++ +  A  TDA  Y C+A N AG+ E  + TL++
Sbjct: 2143 SWFQNG--LPVSPSPRLQVLEEGQVLKVSTAEVTDAANYMCVAENQAGSAEK-LFTLRV 2198



 Score = 68.9 bits (161), Expect = 8e-10
 Identities = 90/337 (26%), Positives = 129/337 (38%), Gaps = 45/337 (13%)

Query: 23   VARHQPATLNCRAGGSPSPAIRWYK-GGVLVVS-DTHRSILPAGGLFFLRATHGRVHSDA 80
            V   Q   L C A G P P I W K GG L      H      G    L+   G   +D+
Sbjct: 2395 VLEGQEVRLGCEAEGQPPPDIAWLKEGGPLDQHVGPHLRFYLDGSTLVLK---GLRAADS 2451

Query: 81   GVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
            G Y C A N  G  AR     + V    ++   +  +  S  G+ V + C P +GSP  +
Sbjct: 2452 GAYTCVAHNPAGEDARLHTVNVLVPPTIKQQASDTGTLVSRTGELVTMMC-PVQGSPPIH 2510

Query: 140  VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
            V W K+G  L     + +H   G  L I   +  D+G + C+A + AG       TL + 
Sbjct: 2511 VSWLKDGLPLALSQRTLLH-NSGRTLRISQVQLADSGVFTCVASSPAGVANRNF-TLLVD 2568

Query: 200  IKPYLITGPEDVVAQTGSSVTFQC-RVGGDPL--PDVLWR--RSAGGGNM---------P 245
                L   P   V +  S     C ++   P+  P+       +A G  +         P
Sbjct: 2569 KGSVLEDSPSVRVPKALSMRATDCAKIQVPPILEPEEFQNDVMAAQGSEVVLPCEARGSP 2628

Query: 246  LGRVKVLDDG------------SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
            L  V  + DG             L+L+ V + D G YSC A +  G       LTV +  
Sbjct: 2629 LPLVSWMKDGEPLLPQSLEQGPGLKLEAVSIGDSGTYSCMAASEAGEARRHFQLTVME-- 2686

Query: 294  SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
             ++L+P       G      C A G P P + W  +G
Sbjct: 2687 -LSLTP-------GAHLELLCEARGIPPPNIIWHKDG 2715



 Score = 66.1 bits (154), Expect = 6e-09
 Identities = 59/222 (26%), Positives = 98/222 (44%), Gaps = 16/222 (7%)

Query: 115  ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLV-IQDARQ 172
            E ++  + +   L C      P P + W + GQ L   DG S   ++ GG ++ +   + 
Sbjct: 2023 EYREVVENNPAYLYC-DTNAIPPPELTWYREGQPLSAVDGVS---VLQGGRILQLPLVQA 2078

Query: 173  TDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP-----EDVVAQTGSSVTFQCRVGG 227
             DAGRY C A N  G  E  +    + + P +I G      E+V     S+V+ +C   G
Sbjct: 2079 EDAGRYSCKASNEVG--EDWLHYELLVLTPPVIPGDTQELVEEVTVNASSAVSLECPALG 2136

Query: 228  DPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGY 286
            +P P + W ++ G    P  R++VL++G  L++    + D   Y C AEN  G+      
Sbjct: 2137 NPAPALSWFQN-GLPVSPSPRLQVLEEGQVLKVSTAEVTDAANYMCVAENQAGSAEKLFT 2195

Query: 287  LTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328
            L V    ++ L+  +   +SG          GR +  +  SV
Sbjct: 2196 LRVQGTHTLRLA-RAQPADSGTYLCEALNPAGRDQKMVQLSV 2236



 Score = 63.3 bits (147), Expect = 4e-08
 Identities = 63/222 (28%), Positives = 93/222 (41%), Gaps = 20/222 (9%)

Query: 259  LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP-NSVNVESGNVARFTCTAT 317
            ++   L DEG Y+C A N  G       L V  PP+I   P N   +E+ +V    C A+
Sbjct: 1445 IEKADLRDEGVYTCSATNLAGESKKDVTLKVLVPPNIEPGPVNKAVLENASVT-LECLAS 1503

Query: 318  GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
            G P P + W  +G + I        + H     DG  VL I     +D+  +  C A N 
Sbjct: 1504 GVPPPDISW-FKGRQPI------STQRHLIVSTDG-RVLHIERAQLSDA-GSYRCVATNV 1554

Query: 378  AGSSFVRGKLTVTSDDDRPPPIITNGPS-NQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436
             GS+ ++  L V       PP IT  PS    + + +     C A  TP P++ W  +G 
Sbjct: 1555 VGSAALQYGLRV-----NVPPRITLPPSLPGPVVLGTPFRLTCNATGTPSPMLLWLKDGN 1609

Query: 437  ALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
             +       +        L +     SD+G Y+CVA S  G+
Sbjct: 1610 PVSPEGTPGLKVFPGGQVLTVASARASDAGGYSCVAVSAVGE 1651



 Score = 61.7 bits (143), Expect = 1e-07
 Identities = 97/372 (26%), Positives = 139/372 (37%), Gaps = 41/372 (11%)

Query: 17   QPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75
            +PL  V+V +   ATL+C A G P P + W + G  V  +    I        L     +
Sbjct: 1853 EPLTTVSVIQDGNATLDCNATGKPLPVVTWERDGQPVRMEL--GIWLQNQNHSLHVDRAQ 1910

Query: 76   VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDTVVLECLPPRG 134
              S AG Y C A N  G A  R A   +A        +  +  +A    ++ L C    G
Sbjct: 1911 A-SHAGGYSCVAENIAGRAERRFALSVLAPPHLTGDSDSLTNVTATLHGSLTLLC-EAEG 1968

Query: 135  SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194
             P P V W + GQ +     + +  V     + Q     DAG ++ +        E A  
Sbjct: 1969 IPPPTVQWFREGQPISPGEGTYLLAVPP---MFQKMGDADAG-FELLPHE-----EEAQG 2019

Query: 195  TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254
                      +T   +VV    + +   C     P P++ W R  G     +  V VL  
Sbjct: 2020 R---------VTEYREVVENNPAYL--YCDTNAIPPPELTWYRE-GQPLSAVDGVSVLQG 2067

Query: 255  GS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI----NLSPNSVNVESGNV 309
            G  L+L  V   D G YSC+A N VG       L V  PP I          V V + + 
Sbjct: 2068 GRILQLPLVQAEDAGRYSCKASNEVGEDWLHYELLVLTPPVIPGDTQELVEEVTVNASSA 2127

Query: 310  ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
                C A G P P + W   G      P +         V +   VL ++  +  D+ N 
Sbjct: 2128 VSLECPALGNPAPALSWFQNGLPVSPSPRLQ--------VLEEGQVLKVSTAEVTDAAN- 2178

Query: 370  IVCSAVNYAGSS 381
             +C A N AGS+
Sbjct: 2179 YMCVAENQAGSA 2190



 Score = 57.2 bits (132), Expect = 3e-06
 Identities = 67/230 (29%), Positives = 88/230 (38%), Gaps = 25/230 (10%)

Query: 292  PPSINLS--PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
            PP I  S      NV  G   R  C A G+P P + W  EG       G      H    
Sbjct: 2381 PPQIQNSGMTQEHNVLEGQEVRLGCEAEGQPPPDIAWLKEGGPLDQHVGP-----HLRFY 2435

Query: 350  FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409
             DG T L +      DS     C A N AG       + V      PP I        TL
Sbjct: 2436 LDGST-LVLKGLRAADS-GAYTCVAHNPAGEDARLHTVNVLV----PPTIKQQASDTGTL 2489

Query: 410  PIKS--MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYT 466
              ++  +    C    +P   ++W  +G  L  + R  + N G TL +  +  +DSG +T
Sbjct: 2490 VSRTGELVTMMCPVQGSPPIHVSWLKDGLPLALSQRTLLHNSGRTLRISQVQLADSGVFT 2549

Query: 467  CVASSRHG-------KYVWSGALLVDSPI--NPNIHFFRAADVSSLPGPP 507
            CVASS  G         V  G++L DSP    P     RA D + +  PP
Sbjct: 2550 CVASSPAGVANRNFTLLVDKGSVLEDSPSVRVPKALSMRATDCAKIQVPP 2599



 Score = 54.4 bits (125), Expect = 2e-05
 Identities = 32/84 (38%), Positives = 42/84 (50%), Gaps = 4/84 (4%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
            +VTV     A L C A G P+P I WYK G L+   +       G    L       HSD
Sbjct: 1352 EVTVLEGHTAQLLCEARGMPAPDITWYKDGTLLAPSSEVIYSKGGRQLQLGKAQ---HSD 1408

Query: 80   AGVYWCEATNSYG-TARSRNATLH 102
            AG+Y C+A+NS G T +S N  ++
Sbjct: 1409 AGLYTCQASNSAGITKKSTNLEVY 1432



 Score = 52.4 bits (120), Expect = 7e-05
 Identities = 57/185 (30%), Positives = 80/185 (43%), Gaps = 15/185 (8%)

Query: 362  DKNDSRNTIV--CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419
            +K D R+  V  CSA N AG S     L V       PP I  GP N+ +   +     C
Sbjct: 1446 EKADLRDEGVYTCSATNLAGESKKDVTLKVLV-----PPNIEPGPVNKAVLENASVTLEC 1500

Query: 420  TAICTPEPIIAWYFEGEALIQNHRRN-VTNDGTLV-LKDLDKSDSGTYTCVASSRHGKYV 477
             A   P P I+W F+G   I   R   V+ DG ++ ++    SD+G+Y CVA++  G   
Sbjct: 1501 LASGVPPPDISW-FKGRQPISTQRHLIVSTDGRVLHIERAQLSDAGSYRCVATNVVGSAA 1559

Query: 478  WSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDT-SVTLSW-SQNNKIGSSSI 535
                L V+ P  P I    +     + G P + +T N T T S  L W    N +     
Sbjct: 1560 LQYGLRVNVP--PRITLPPSLPGPVVLGTPFR-LTCNATGTPSPMLLWLKDGNPVSPEGT 1616

Query: 536  LGYQV 540
             G +V
Sbjct: 1617 PGLKV 1621



 Score = 50.8 bits (116), Expect = 2e-04
 Identities = 41/128 (32%), Positives = 55/128 (42%), Gaps = 11/128 (8%)

Query: 78   SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA----QGDTVVLECLPPR 133
            +D+G Y CEA N  G  R +       ++   F+  P   Q A     GD   L C    
Sbjct: 2212 ADSGTYLCEALNPAG--RDQKMVQLSVLVPPSFKQAPGGPQEAVQVRAGDKATLNC-ETD 2268

Query: 134  GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
              PEP V W K+ Q L   G     L  G  L I D++ +D G Y C   N AG    A 
Sbjct: 2269 SLPEPAVTWFKDQQPLAL-GQRIQGLQGGQKLEILDSQVSDKGVYSCKVSNTAG---EAT 2324

Query: 194  ATLKIHIK 201
             T +++I+
Sbjct: 2325 RTFELNIQ 2332



 Score = 49.2 bits (112), Expect = 7e-04
 Identities = 36/126 (28%), Positives = 57/126 (45%), Gaps = 9/126 (7%)

Query: 170  ARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP----EDVVAQTGSSVTFQCRV 225
            A+  D+G Y C A N AG R+  +  L + + P     P    E V  + G   T  C  
Sbjct: 2209 AQPADSGTYLCEALNPAG-RDQKMVQLSVLVPPSFKQAPGGPQEAVQVRAGDKATLNCET 2267

Query: 226  GGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSA 283
               P P V W +      + LG R++ L  G  L + +  ++D+G YSC+  N+ G  + 
Sbjct: 2268 DSLPEPAVTWFKDQQP--LALGQRIQGLQGGQKLEILDSQVSDKGVYSCKVSNTAGEATR 2325

Query: 284  SGYLTV 289
            +  L +
Sbjct: 2326 TFELNI 2331



 Score = 48.8 bits (111), Expect = 9e-04
 Identities = 40/135 (29%), Positives = 61/135 (45%), Gaps = 10/135 (7%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
            V  G+   ++E+   VTV      +L C A G+P+PA+ W++ G+ V       +L  G 
Sbjct: 2108 VIPGDTQELVEE---VTVNASSAVSLECPALGNPAPALSWFQNGLPVSPSPRLQVLEEGQ 2164

Query: 66   LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
            +  L+ +   V +DA  Y C A N  G+A  +  TL V   +    L     Q A   T 
Sbjct: 2165 V--LKVSTAEV-TDAANYMCVAENQAGSA-EKLFTLRV---QGTHTLRLARAQPADSGTY 2217

Query: 126  VLECLPPRGSPEPNV 140
            + E L P G  +  V
Sbjct: 2218 LCEALNPAGRDQKMV 2232



 Score = 48.8 bits (111), Expect = 9e-04
 Identities = 42/130 (32%), Positives = 55/130 (42%), Gaps = 20/130 (15%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
            DV  A+     L C A GSP P + W K G  ++    +S+    GL     + G    D
Sbjct: 2609 DVMAAQGSEVVLPCEARGSPLPLVSWMKDGEPLLP---QSLEQGPGLKLEAVSIG----D 2661

Query: 80   AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
            +G Y C A +  G AR      H  +   E  L P       G  + L C   RG P PN
Sbjct: 2662 SGTYSCMAASEAGEARR-----HFQLTVMELSLTP-------GAHLELLC-EARGIPPPN 2708

Query: 140  VYWKKNGQTL 149
            + W K+GQ L
Sbjct: 2709 IIWHKDGQAL 2718



 Score = 47.6 bits (108), Expect = 0.002
 Identities = 30/90 (33%), Positives = 39/90 (43%), Gaps = 4/90 (4%)

Query: 241  GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP- 299
            G    L  ++V    +LRL     AD G Y CEA N  G       L+V  PPS   +P 
Sbjct: 2188 GSAEKLFTLRVQGTHTLRLARAQPADSGTYLCEALNPAGRDQKMVQLSVLVPPSFKQAPG 2247

Query: 300  ---NSVNVESGNVARFTCTATGRPEPTMFW 326
                +V V +G+ A   C     PEP + W
Sbjct: 2248 GPQEAVQVRAGDKATLNCETDSLPEPAVTW 2277



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 32/129 (24%), Positives = 52/129 (40%), Gaps = 11/129 (8%)

Query: 352  GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN--QTL 409
            G   L +      DS  T +C A+N AG      +L+V       PP     P    + +
Sbjct: 2200 GTHTLRLARAQPADS-GTYLCEALNPAGRDQKMVQLSVLV-----PPSFKQAPGGPQEAV 2253

Query: 410  PIKS--MAVFPCTAICTPEPIIAWYFEGEALIQNHR-RNVTNDGTLVLKDLDKSDSGTYT 466
             +++   A   C     PEP + W+ + + L    R + +     L + D   SD G Y+
Sbjct: 2254 QVRAGDKATLNCETDSLPEPAVTWFKDQQPLALGQRIQGLQGGQKLEILDSQVSDKGVYS 2313

Query: 467  CVASSRHGK 475
            C  S+  G+
Sbjct: 2314 CKVSNTAGE 2322



 Score = 37.5 bits (83), Expect = 2.2
 Identities = 25/74 (33%), Positives = 32/74 (43%), Gaps = 3/74 (4%)

Query: 21   VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
            V V     ATLNC     P PA+ W+K    +        L  G    L     +V SD 
Sbjct: 2253 VQVRAGDKATLNCETDSLPEPAVTWFKDQQPLALGQRIQGLQGGQK--LEILDSQV-SDK 2309

Query: 81   GVYWCEATNSYGTA 94
            GVY C+ +N+ G A
Sbjct: 2310 GVYSCKVSNTAGEA 2323


>UniRef50_Q4S8U5 Cluster: Chromosome 7 SCAF14703, whole genome shotgun
            sequence; n=5; Tetraodontidae|Rep: Chromosome 7
            SCAF14703, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 2095

 Score =  170 bits (414), Expect = 2e-40
 Identities = 205/832 (24%), Positives = 342/832 (41%), Gaps = 67/832 (8%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
            D+T    +   + CR  G P  +I+W K G + + D HR ++   G   LR T  +  +D
Sbjct: 516  DMTAVAGRNTYITCRVIGYPYYSIKWLKDG-MQLPDNHRQVVFENGT--LRLTDVQKGAD 572

Query: 80   AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
             G Y C          S N T+HV V         +   ++ G  + + C+   G     
Sbjct: 573  EGTYLCSVLIQPQV--SINQTVHVTVKVPPLIQPFDIPSTSVGKLIYIACVVSSGDMPIR 630

Query: 140  VYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
            + W K+GQ ++    S + +       +L I        G Y CIA N A T  S    L
Sbjct: 631  ITWHKDGQPIVPGSASGVAIETKDFMSSLQITKVTLKHNGNYTCIASNTAAT-VSWERQL 689

Query: 197  KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN------MPL-GRV 249
             + + P  +  P +     G +    C V G P P V+W+ + G GN      +PL GR+
Sbjct: 690  IVTVPPRFVVQPNNQDCIYGKAGVLNCSVEGYPPPKVMWKHAKGVGNPQQYHPVPLTGRI 749

Query: 250  KVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSAS-GYLTVYDPPSINLSPNSVNVESG 307
            +++ +GSL + +V+  D G Y C+A N VG+ +S    ++TV  P  I   PN+     G
Sbjct: 750  QIMSNGSLLIRHVLEEDRGYYLCQASNGVGSDISREHDHVTVKIPAMITSHPNTTMARKG 809

Query: 308  NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG---VTVLTINDTDKN 364
                  CTA G     + W  E   T+I       +Y  T    G   ++ L +N  ++ 
Sbjct: 810  QTKELNCTARGEQPIIIRW--ERGDTVI-DAERNPRYSITINKKGDEVISTLKLNPAERG 866

Query: 365  DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
            DS     C A+N  G      +LTV    D PP +      ++++ ++ +  F   +I T
Sbjct: 867  DSV-FFSCHAINSYGEGRGLIQLTVQEPPD-PPELEVREVKDRSMNLRWIQRFDGNSIIT 924

Query: 425  PEPIIAWYFEGEALIQNHR---RNV--TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479
               I    ++ ++   +H    RN+  TN+   ++ +L  +      CV S R   Y   
Sbjct: 925  SYDI---EYKNKSDSWDHMYTTRNISPTNNQANIV-ELHPA------CVYSIRMYSYNKI 974

Query: 480  GALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK-IGSSSILGY 538
            G  L      P+     + + +   GPP   I   +T  S+ ++W    K + +  I GY
Sbjct: 975  GRSL------PSKELTISTEEAPPDGPPMDVILQPMTSQSIRVTWRAPKKELQNGVIRGY 1028

Query: 539  QVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
            Q+    RE   G+N        V +        Y + +L     Y  +V+  N  G +GP
Sbjct: 1029 QIGY--RENGPGSN---GQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAG-TGP 1082

Query: 599  SPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEI--- 655
            S    + T  +D ++  +       +      +     + + A  + S    + W     
Sbjct: 1083 SSTEINATTLEDEDARKQRPSAITDSYPPLFPVPSEPPQNVRAISVTSDEAVITWSEPPR 1142

Query: 656  LNFY-YLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKF 714
            L  +  L+G  + F  L +     EM+ I  + +    E+  L K+T Y   ++ + +  
Sbjct: 1143 LTLHGVLKGYRVVFWSLFSNGEWGEMQNITTTREQ--VELRGLEKFTNYSVQVLAYTQAG 1200

Query: 715  EGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWL 774
            +G  SN    QT +D+P GPP  I+    + ++V + W PP     NGII  Y +   + 
Sbjct: 1201 DGVRSNVLYIQTREDLP-GPPAGIKAVPSSPSSVVVSWLPP--NKPNGIIRKYTI---YC 1254

Query: 775  DVPANKSMVAINTTVH-QATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
              P +          + +     +T+L+ G  Y +  AA T  G G FS KV
Sbjct: 1255 SSPGSGQPAPSEYEANPEMLFYRITHLSRGKQYHIWAAAVTTAGKGNFSSKV 1306



 Score =  123 bits (296), Expect = 3e-26
 Identities = 138/538 (25%), Positives = 218/538 (40%), Gaps = 63/538 (11%)

Query: 13  YIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAGGLFFL- 69
           Y +   L  VT +     +L C AGG+PS  +RWY   G  +    H   + A G   L 
Sbjct: 9   YFVNASLQRVTYSSSVGVSLPCPAGGTPSAILRWYLATGDDIYDVPHIRHVHANGTLQLY 68

Query: 70  ----RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
                A +  +H +   Y+C A N  G  RS N  +  AV RE + +    ++S +G+  
Sbjct: 69  PFSPSAYNSYIHDND--YFCTAENQAGKIRSPNIRIK-AVFREPYTVRVADQRSMRGNVA 125

Query: 126 VLECLPPRGSPE--PNVYWKKNGQTLLFDGD------SRMH------------LVDGGNL 165
           V +CL P    E    V W+++  +++ + D      +R+H            L   G L
Sbjct: 126 VFKCLIPAAVQEYVSVVSWERDTVSIVPEDDRSVWDWTRLHPGSTGIPGNRFSLTSFGAL 185

Query: 166 VIQDARQTDA-GRYQCIARN--AAGTRESAIATLKI----HIKPYLITGPEDVVAQTGSS 218
            I + ++ DA   Y+CI R+  +  TR+S  A L +       P ++   +      G S
Sbjct: 186 YISEVQKEDALSTYRCITRHKYSGETRQSNGARLSVMDPNESSPTILDSFQAGEVYAGQS 245

Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSV 278
           +   C  GG P P V W +   G  +P           L + ++ L D G Y+CE  NS 
Sbjct: 246 IELPCIAGGYPNPTVRWLKD--GRPLPSDARWTRRLTGLTISDLRLEDSGSYACEVTNSF 303

Query: 279 GAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPG 338
           G+   SG L V DP  + LSP ++     +   FTC+  G PE T+ W    N  +I P 
Sbjct: 304 GSKEVSGQLHVIDPLRVTLSPKNLKTGISSTLFFTCSVEGSPEYTITWF--RNTELIVPD 361

Query: 339 MSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398
                 H +        L I    K  S     C A   +         ++   +D  P 
Sbjct: 362 Q-----HISIQGQNNDTLQITAAQKFHS-GAYQCFA---SRKGHTAQDFSIILLEDGTPR 412

Query: 399 IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT----NDGTLV- 453
           I+++       P +  ++  C A   P P I W  + E ++++     +    +DG  V 
Sbjct: 413 IVSSFSERVVNPGEPFSLM-CAAKGAPPPSITWTLDDEPVVRDSTYKTSQYTLSDGLTVS 471

Query: 454 ---LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPT 508
              +      D G Y CVA +  G   +   + V  P  P I   R  D++++ G  T
Sbjct: 472 HVNVSSPHIRDGGVYRCVARNSAGSAEYQARINVRGP--PRIRPMR--DMTAVAGRNT 525



 Score =  122 bits (293), Expect = 8e-26
 Identities = 121/490 (24%), Positives = 192/490 (39%), Gaps = 36/490 (7%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
           +P I++      V   Q   L C AGG P+P +RW K G  + SD   +    G    L 
Sbjct: 228 SPTILDSFQAGEVYAGQSIELPCIAGGYPNPTVRWLKDGRPLPSDARWTRRLTG----LT 283

Query: 71  ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
            +  R+  D+G Y CE TNS+G+ +  +  LHV +      L P++ ++    T+   C 
Sbjct: 284 ISDLRLE-DSGSYACEVTNSFGS-KEVSGQLHV-IDPLRVTLSPKNLKTGISSTLFFTC- 339

Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
              GSPE  + W +N + ++ D    +   +   L I  A++  +G YQC A     T +
Sbjct: 340 SVEGSPEYTITWFRNTELIVPDQHISIQGQNNDTLQITAAQKFHSGAYQCFASRKGHTAQ 399

Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR---RSAGGGNMPLG 247
                L     P +++   + V   G   +  C   G P P + W          +    
Sbjct: 400 DFSIILLEDGTPRIVSSFSERVVNPGEPFSLMCAAKGAPPPSITWTLDDEPVVRDSTYKT 459

Query: 248 RVKVLDDG----SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
               L DG     + + +  + D G Y C A NS G+      + V  PP I      + 
Sbjct: 460 SQYTLSDGLTVSHVNVSSPHIRDGGVYRCVARNSAGSAEYQARINVRGPPRIR-PMRDMT 518

Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
             +G     TC   G P  ++ W        +  GM     H   VF+  T L + D  K
Sbjct: 519 AVAGRNTYITCRVIGYPYYSIKW--------LKDGMQLPDNHRQVVFENGT-LRLTDVQK 569

Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
                T +CS +     S +   + VT    + PP+I       T  +  +    C    
Sbjct: 570 GADEGTYLCSVLIQPQVS-INQTVHVTV---KVPPLIQPFDIPST-SVGKLIYIACVVSS 624

Query: 424 TPEPI-IAWYFEGEALIQNHRRNV---TND--GTLVLKDLDKSDSGTYTCVASSRHGKYV 477
              PI I W+ +G+ ++      V   T D   +L +  +    +G YTC+AS+      
Sbjct: 625 GDMPIRITWHKDGQPIVPGSASGVAIETKDFMSSLQITKVTLKHNGNYTCIASNTAATVS 684

Query: 478 WSGALLVDSP 487
           W   L+V  P
Sbjct: 685 WERQLIVTVP 694



 Score =  110 bits (264), Expect = 3e-22
 Identities = 210/871 (24%), Positives = 345/871 (39%), Gaps = 128/871 (14%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P I+    +  V   +P +L C A G+P P+I W      VV D+            L  
Sbjct: 411  PRIVSSFSERVVNPGEPFSLMCAAKGAPPPSITWTLDDEPVVRDSTYKTSQYTLSDGLTV 470

Query: 72   THGRVHS----DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVV 126
            +H  V S    D GVY C A NS G+A  + A ++V   R   R+ P    +A  G    
Sbjct: 471  SHVNVSSPHIRDGGVYRCVARNSAGSAEYQ-ARINV---RGPPRIRPMRDMTAVAGRNTY 526

Query: 127  LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ-TDAGRYQC--IAR 183
            + C    G P  ++ W K+G  L    + R  + + G L + D ++  D G Y C  + +
Sbjct: 527  ITCRVI-GYPYYSIKWLKDGMQL--PDNHRQVVFENGTLRLTDVQKGADEGTYLCSVLIQ 583

Query: 184  NAAGTRESAIATLKIHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLP-DVLWRRSAGG 241
                  ++   T+K+   P LI  P D+ + + G  +   C V    +P  + W +    
Sbjct: 584  PQVSINQTVHVTVKV---PPLIQ-PFDIPSTSVGKLIYIACVVSSGDMPIRITWHKDGQP 639

Query: 242  ---GNMPLGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
               G+     ++  D   SL++  V L   G Y+C A N+   VS    L V  PP   +
Sbjct: 640  IVPGSASGVAIETKDFMSSLQITKVTLKHNGNYTCIASNTAATVSWERQLIVTVPPRFVV 699

Query: 298  SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
             PN+ +   G      C+  G P P + W  +  + +  P     +YH   +   + +++
Sbjct: 700  QPNNQDCIYGKAGVLNCSVEGYPPPKVMW--KHAKGVGNP----QQYHPVPLTGRIQIMS 753

Query: 358  INDT----DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413
                       + R   +C A N  GS   R    VT    + P +IT+ P N T+  K 
Sbjct: 754  NGSLLIRHVLEEDRGYYLCQASNGVGSDISREHDHVTV---KIPAMITSHP-NTTMARKG 809

Query: 414  MA-VFPCTAICTPEPIIAWYFEGEALI---QNHRRNVTND-------GTLVLKDLDKSDS 462
                  CTA    +PII  +  G+ +I   +N R ++T +        TL L   ++ DS
Sbjct: 810  QTKELNCTA-RGEQPIIIRWERGDTVIDAERNPRYSITINKKGDEVISTLKLNPAERGDS 868

Query: 463  GTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTL 522
              ++C A + +G+      L V  P                P PP   +   V D S+ L
Sbjct: 869  VFFSCHAINSYGEGRGLIQLTVQEP----------------PDPPELEV-REVKDRSMNL 911

Query: 523  SWSQNNKIGSSSILGYQVEVFSR-ETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGI 581
             W Q    G+S I  Y +E  ++ ++     T RN      I+   +Q + V   L P  
Sbjct: 912  RWIQRFD-GNSIITSYDIEYKNKSDSWDHMYTTRN------ISPTNNQANIV--ELHPAC 962

Query: 582  TYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEA 641
             Y   + + N  G S P   S  +T+  +  +  +G  +            D I++    
Sbjct: 963  VYSIRMYSYNKIGRSLP---SKELTISTE-EAPPDGPPM------------DVILQ---- 1002

Query: 642  TPIDSKTIKLMWEI----LNFYYLEGLFIYFRPL-DNITIEYEMKTILHSNDVSGFEITS 696
             P+ S++I++ W      L    + G  I +R        +Y +  +  + D   + + +
Sbjct: 1003 -PMTSQSIRVTWRAPKKELQNGVIRGYQIGYRENGPGSNGQYSIVEMKATGDSEVYTLDN 1061

Query: 697  LRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDD--------------------VPDGPPI 736
            L+K+ +Y   +  F +   G  S    A TL+D                    VP  PP 
Sbjct: 1062 LKKFAQYGVVVQAFNRAGTGPSSTEINATTLEDEDARKQRPSAITDSYPPLFPVPSEPPQ 1121

Query: 737  NIEMFILNTTTVHLKWS-PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSL 795
            N+    + +    + WS PP L L +G++ GY VV  W  + +N     +         +
Sbjct: 1122 NVRAISVTSDEAVITWSEPPRLTL-HGVLKGYRVVF-W-SLFSNGEWGEMQNITTTREQV 1178

Query: 796  IMTNLTSGVSYSVQIAAETIIGLGPFSQKVY 826
             +  L    +YSVQ+ A T  G G  S  +Y
Sbjct: 1179 ELRGLEKFTNYSVQVLAYTQAGDGVRSNVLY 1209



 Score =  108 bits (259), Expect = 1e-21
 Identities = 141/571 (24%), Positives = 230/571 (40%), Gaps = 38/571 (6%)

Query: 83  YWCEATNSYG--TARSRNATLHVAVLREEFRLEPESKQSAQ---GDTVVLECLPPRGSPE 137
           Y C   + Y   T +S  A L V    E      +S Q+ +   G ++ L C+   G P 
Sbjct: 199 YRCITRHKYSGETRQSNGARLSVMDPNESSPTILDSFQAGEVYAGQSIELPCIAG-GYPN 257

Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
           P V W K+G+ L  D      L     L I D R  D+G Y C   N+ G++E +   L 
Sbjct: 258 PTVRWLKDGRPLPSDARWTRRLT---GLTISDLRLEDSGSYACEVTNSFGSKEVS-GQLH 313

Query: 198 IHIKPYLIT-GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDD 254
           + I P  +T  P+++     S++ F C V G P   + W R+     +P   + +   ++
Sbjct: 314 V-IDPLRVTLSPKNLKTGISSTLFFTCSVEGSPEYTITWFRNT-ELIVPDQHISIQGQNN 371

Query: 255 GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLSPNSVNVESGNVARFT 313
            +L++        G Y C A            + + D  P I  S +   V  G      
Sbjct: 372 DTLQITAAQKFHSGAYQCFASRKGHTAQDFSIILLEDGTPRIVSSFSERVVNPGEPFSLM 431

Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV-C 372
           C A G P P++ W+++    +        +Y    + DG+TV  +N +  +     +  C
Sbjct: 432 CAAKGAPPPSITWTLDDEPVVRDSTYKTSQY---TLSDGLTVSHVNVSSPHIRDGGVYRC 488

Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
            A N AGS+  + ++ V     R PP I     + T          C  I  P   I W 
Sbjct: 489 VARNSAGSAEYQARINV-----RGPPRI-RPMRDMTAVAGRNTYITCRVIGYPYYSIKWL 542

Query: 433 FEGEALIQNHRRNVTNDGTLVLKDLDK-SDSGTYTCVASSRHGKYVWSGALLVDSPINPN 491
            +G  L  NHR+ V  +GTL L D+ K +D GTY C    +    + +  + V   + P 
Sbjct: 543 KDGMQLPDNHRQVVFENGTLRLTDVQKGADEGTYLCSVLIQPQVSI-NQTVHVTVKVPPL 601

Query: 492 IHFFRAADVSSLPGPPTKPITHNVT--DTSVTLSWSQNNK---IGSSSILGYQVEVFSRE 546
           I  F   D+ S        I   V+  D  + ++W ++ +    GS+S +  + + F   
Sbjct: 602 IQPF---DIPSTSVGKLIYIACVVSSGDMPIRITWHKDGQPIVPGSASGVAIETKDFMSS 658

Query: 547 TLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD-SV 605
                 T +++  +  IA     T    + LI  +   F+V+  N   + G + V + SV
Sbjct: 659 LQITKVTLKHNGNYTCIASNTAATVSWERQLIVTVPPRFVVQPNNQDCIYGKAGVLNCSV 718

Query: 606 TVGDDSNSLWE-GTGVSNSTEYRNNILTDHI 635
                   +W+   GV N  +Y    LT  I
Sbjct: 719 EGYPPPKVMWKHAKGVGNPQQYHPVPLTGRI 749



 Score = 56.4 bits (130), Expect = 4e-06
 Identities = 51/178 (28%), Positives = 85/178 (47%), Gaps = 27/178 (15%)

Query: 370  IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
            I  +AV  AG      K+TV      P  I++ G +  T  +K + + PC+++  P P I
Sbjct: 1289 IWAAAVTTAGKGNFSSKVTVEPAGKVPAKILSFGGTVTTPWMKEVRL-PCSSVGEPAPTI 1347

Query: 430  AWYFEGE----ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485
             W  + E     +  + +R V ++GTLVL+ +   DSG YTC A++  G       ++V+
Sbjct: 1348 KWTKDSEDSAVPVTSDSQRQVLSNGTLVLRSVKAEDSGYYTCTATNTLG----FDTIIVN 1403

Query: 486  SPINPNIHFFRAADVSSLPGPPTKP-ITHNVTDT-SVTLSWSQNNKIGSSSILGYQVE 541
              +                 PP +P +T + T T S+TL+W   +  G SSI G+ ++
Sbjct: 1404 LVVQV---------------PPDQPRLTVSTTSTSSITLAWIPGDN-GGSSIRGFVLQ 1445



 Score = 43.6 bits (98), Expect = 0.034
 Identities = 26/97 (26%), Positives = 44/97 (45%), Gaps = 6/97 (6%)

Query: 134  GSPEPNVYWKKNGQ--TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
            G P P + W K+ +   +    DS+  ++  G LV++  +  D+G Y C A N  G  ++
Sbjct: 1341 GEPAPTIKWTKDSEDSAVPVTSDSQRQVLSNGTLVLRSVKAEDSGYYTCTATNTLGF-DT 1399

Query: 192  AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228
             I  L + + P     P   V+ T +S      + GD
Sbjct: 1400 IIVNLVVQVPP---DQPRLTVSTTSTSSITLAWIPGD 1433



 Score = 42.7 bits (96), Expect = 0.059
 Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 8/76 (10%)

Query: 21   VTVARHQPATLNCRAGGSPSPAIRWYK----GGVLVVSDTHRSILPAGGLFFLRATHGRV 76
            VT    +   L C + G P+P I+W K      V V SD+ R +L + G   LR+     
Sbjct: 1325 VTTPWMKEVRLPCSSVGEPAPTIKWTKDSEDSAVPVTSDSQRQVL-SNGTLVLRSVKA-- 1381

Query: 77   HSDAGVYWCEATNSYG 92
              D+G Y C ATN+ G
Sbjct: 1382 -EDSGYYTCTATNTLG 1396



 Score = 42.3 bits (95), Expect = 0.078
 Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 3/78 (3%)

Query: 219  VTFQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAE 275
            V   C   G+P P + W + +    +P+    + +VL +G+L L +V   D G Y+C A 
Sbjct: 1333 VRLPCSSVGEPAPTIKWTKDSEDSAVPVTSDSQRQVLSNGTLVLRSVKAEDSGYYTCTAT 1392

Query: 276  NSVGAVSASGYLTVYDPP 293
            N++G  +    L V  PP
Sbjct: 1393 NTLGFDTIIVNLVVQVPP 1410


>UniRef50_UPI00004DA303 Cluster: UPI00004DA303 related cluster; n=2;
            Xenopus tropicalis|Rep: UPI00004DA303 UniRef100 entry -
            Xenopus tropicalis
          Length = 2690

 Score =  170 bits (413), Expect = 2e-40
 Identities = 144/460 (31%), Positives = 203/460 (44%), Gaps = 41/460 (8%)

Query: 31   LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
            L+C A GSPSP +   K G  + S      +    L   R       S AG Y C A NS
Sbjct: 1151 LSCEAEGSPSPVVTSLKDGEPLDSGVWGVAIRGSRLQITRVQQ----SHAGRYRCIAQNS 1206

Query: 91   YGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLECLPPRGSPEPNVYWKKNGQ-- 147
                  ++  L V V    F  E  S+ S  +   V LEC    G+P P + W K+G   
Sbjct: 1207 ISETH-KDFVLLVQVAPRIFGSEMPSEHSVPEKQEVKLEC-KTEGTPAPQILWFKDGNPL 1264

Query: 148  --TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL- 204
              TL+ +    +   DG  LV++  + +D+GRY C+ARN AG  ++ +  L I   P L 
Sbjct: 1265 DVTLVPNTSGNLTKQDGNFLVLRSVQASDSGRYTCVARNNAG-EDTRVYVLNILGLPVLE 1323

Query: 205  -ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVI 263
                 E+V A  G+SVTF C   G PLP + W +     N+    +       L L++V 
Sbjct: 1324 RSESTEEVTAIKGASVTFTCEAHGTPLPSLSWEKDGQPLNLQSNLLPNGLGTRLHLESVR 1383

Query: 264  LADEGEYSCEAENSVGAVSASGYLTVYDPPSIN--LSPNSVNVESGNVARFTCTATGRPE 321
              D G YSC A N+ G VS   +LTV +PP I     P  V++ + +     CTATG P 
Sbjct: 1384 ALDSGIYSCIAVNAAGRVSKHFHLTVLEPPRIEGPALPTEVSIIADSPLELACTATGVPT 1443

Query: 322  PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG-- 379
            P + W  +G          R   H   +    TVL I      D+    VC A + AG  
Sbjct: 1444 PEISWEKDG----------RPLSHPDLLTRNGTVLRIERVKAEDA-GIYVCVATSTAGRD 1492

Query: 380  --SSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436
              +++VR K+        PP ++ +  P +  + +    V  C     P P I WY    
Sbjct: 1493 SRATWVRMKV--------PPSVVGSTEPRSLAVSVGGQLVLECKVEADPPPTIQWYRGDI 1544

Query: 437  ALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHGK 475
             L  + R  V + G  V +  L  SDSG YTC+AS+  G+
Sbjct: 1545 PLQTDGRVQVLSKGRYVQIHSLRPSDSGEYTCIASNPAGR 1584



 Score =  139 bits (336), Expect = 5e-31
 Identities = 125/481 (25%), Positives = 206/481 (42%), Gaps = 39/481 (8%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P I+ + L+ ++A +QP  L C++   P P I W K G  ++      ++  G   +L+ 
Sbjct: 376 PTIMGEELNSSIAVNQPLLLECQSTAIPPPLITWLKDGRPLLQRPGVQVIDDG--HYLQI 433

Query: 72  THGRVHSDAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
              ++  DAG Y CEA+N  G T +  N  +    +       P+     +G  V +EC+
Sbjct: 434 DQAQLR-DAGRYTCEASNDAGRTEKHYNVIIWAQPMIAGSSNTPKQLMVNKGSLVTMECV 492

Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
              G P P+V W K+G   L +G        G  L I  A+ + +GRY C+A NAAG  +
Sbjct: 493 -VSGKPSPSVTWLKDGYP-LGNGPDLFFQNKGQQLTILKAQPSHSGRYVCVAVNAAGQTD 550

Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGS---SVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
                  + + P L     +++  + S   + T  C   G P P + W R+      P  
Sbjct: 551 IKYEVF-VQVPPELPNTQTELLNVSTSLHGTFTITCEATGIPPPVITWFRN-NEALSPRE 608

Query: 248 RVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN-LSPNSVNVE 305
            V +   G  LR+ +  + D G Y+C   N+ G      ++ +  PPSI+    N + V 
Sbjct: 609 NVHLQSGGRVLRITHAQIQDAGHYTCVVTNTAGQAKKDFFVDILVPPSIDGEDDNDLRVP 668

Query: 306 SGNVARFTCTATGRPEPTMFWSVE------GNRTIIFPGMSRDKYHATAVFD--GVTVLT 357
            G     +C  +G P+P + W  +      G+  +I P  S     +  VF+    T + 
Sbjct: 669 EGQSVTLSCKVSGHPKPLITWLRDSQPVQSGDEVLISPDGSELHIQSANVFNVGHYTCIA 728

Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
           IN   +  SR+ IV   V    S  + G L   +++D    +I N P +           
Sbjct: 729 INSIAER-SRSYIVTVLV----SPTISGPLDDEANED--VIVIVNNPFS----------L 771

Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKY 476
            C A+  P P + W   GE    +    +   G  L + +  + DSG YTCV ++  G+ 
Sbjct: 772 ICEALGFPIPSVTWLKNGEPFKDSDNLRLLPGGHGLQILNAQEEDSGQYTCVVTNEVGEA 831

Query: 477 V 477
           +
Sbjct: 832 I 832



 Score =  138 bits (335), Expect = 6e-31
 Identities = 125/465 (26%), Positives = 188/465 (40%), Gaps = 31/465 (6%)

Query: 20  DVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFLRATHGRVHS 78
           D+T        L+C+A G P P + W K G  L   D H  +   G +  L  T     S
Sbjct: 12  DMTARDGSEVELHCKASGVPRPQVEWTKDGQPLPPGDAHIQLTEGGQVLQLNGTR---LS 68

Query: 79  DAGVYWCEATNSYGT-ARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
           D G Y C A N  G   +  N  +H            E      G TV L C   R SP 
Sbjct: 69  DQGRYQCLAFNHAGQQVKDFNLRVHTPPTIWASNETTEVASLLHG-TVELRC-EARASPV 126

Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
           P + W K+ + ++    SR    +GG +L +     +D G Y C A N AGT E +   L
Sbjct: 127 PGITWFKDKRPIV--SSSRATYREGGRSLQLSRVLLSDVGTYTCRATNNAGTAEKSYR-L 183

Query: 197 KIHIKPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254
           ++++ P ++ G   E V       +   C   G P P + W R+    +   G V+VL+ 
Sbjct: 184 EVYVPPKVVIGEGSEHVTVTANDPLDLSCHATGYPTPTIQWLRNNHSLSHEDG-VEVLNG 242

Query: 255 ---GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVAR 311
                L++++   +D GEY C A N+ G+      L V   P I    +           
Sbjct: 243 VQGPKLQIESAKSSDSGEYRCVASNTAGSTELQYNLLVNVAPRIVSMMDFATFLVNEQVW 302

Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371
             C ATG PEP + W  +  +  +   ++        + +   +L++     +DS     
Sbjct: 303 LECNATGVPEPAIMWLKD--QVPVSTAIA-----GLQIMEQGRILSLRAAHVSDS-GIYS 354

Query: 372 CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431
           C AVN AG       L V       PP I     N ++ +    +  C +   P P+I W
Sbjct: 355 CVAVNPAGEDSHHIALQVFV-----PPTIMGEELNSSIAVNQPLLLECQSTAIPPPLITW 409

Query: 432 YFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGK 475
             +G  L+Q     V +DG  L +      D+G YTC AS+  G+
Sbjct: 410 LKDGRPLLQRPGVQVIDDGHYLQIDQAQLRDAGRYTCEASNDAGR 454



 Score =  132 bits (319), Expect = 6e-29
 Identities = 137/472 (29%), Positives = 195/472 (41%), Gaps = 39/472 (8%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFL 69
           AP I+      T   ++   L C A G P PAI W K  V V  +     I+  G +  L
Sbjct: 283 APRIVSMMDFATFLVNEQVWLECNATGVPEPAIMWLKDQVPVSTAIAGLQIMEQGRILSL 342

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
           RA H    SD+G+Y C A N  G   S +  L V V       E  +   A    ++LEC
Sbjct: 343 RAAH---VSDSGIYSCVAVNPAG-EDSHHIALQVFV-PPTIMGEELNSSIAVNQPLLLEC 397

Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
                 P P + W K+G+ LL     ++ + DG  L I  A+  DAGRY C A N AG  
Sbjct: 398 -QSTAIPPPLITWLKDGRPLLQRPGVQV-IDDGHYLQIDQAQLRDAGRYTCEASNDAGRT 455

Query: 190 ESAIATLKIHIKPYLITG----PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
           E     + I  +P +I G    P+ ++   GS VT +C V G P P V W +       P
Sbjct: 456 EKHYNVI-IWAQP-MIAGSSNTPKQLMVNKGSLVTMECVVSGKPSPSVTWLKD----GYP 509

Query: 246 LGRVKVL---DDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-NLSPN 300
           LG    L   + G  L +     +  G Y C A N+ G       + V  PP + N    
Sbjct: 510 LGNGPDLFFQNKGQQLTILKAQPSHSGRYVCVAVNAAGQTDIKYEVFVQVPPELPNTQTE 569

Query: 301 SVNVESGNVARF--TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
            +NV +     F  TC ATG P P + W    N   + P   R+  H  +   G  VL I
Sbjct: 570 LLNVSTSLHGTFTITCEATGIPPPVITWF--RNNEALSP---RENVHLQS---GGRVLRI 621

Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
                 D+ +   C   N AG    + K     D   PP I     ++  +P        
Sbjct: 622 THAQIQDAGH-YTCVVTNTAG----QAKKDFFVDILVPPSIDGEDDNDLRVPEGQSVTLS 676

Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVA 469
           C     P+P+I W  + + +       ++ DG+ L ++  +  + G YTC+A
Sbjct: 677 CKVSGHPKPLITWLRDSQPVQSGDEVLISPDGSELHIQSANVFNVGHYTCIA 728



 Score =  132 bits (318), Expect = 7e-29
 Identities = 122/481 (25%), Positives = 205/481 (42%), Gaps = 39/481 (8%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            E P    + L+V+ + H   T+ C A G P P I W++     +S      L +GG   L
Sbjct: 562  ELPNTQTELLNVSTSLHGTFTITCEATGIPPPVITWFRNNE-ALSPRENVHLQSGGR-VL 619

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
            R TH ++  DAG Y C  TN+ G A+ ++  + + V       +    +  +G +V L C
Sbjct: 620  RITHAQI-QDAGHYTCVVTNTAGQAK-KDFFVDILVPPSIDGEDDNDLRVPEGQSVTLSC 677

Query: 130  LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
                G P+P + W ++ Q +   GD  +   DG  L IQ A   + G Y CIA N+   R
Sbjct: 678  -KVSGHPKPLITWLRDSQPVQ-SGDEVLISPDGSELHIQSANVFNVGHYTCIAINSIAER 735

Query: 190  ESAIATLKIHIKPYLITGP------EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
             S    + + + P  I+GP      EDV+    +  +  C   G P+P V W ++ G   
Sbjct: 736  -SRSYIVTVLVSP-TISGPLDDEANEDVIVIVNNPFSLICEALGFPIPSVTWLKN-GEPF 792

Query: 244  MPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI------- 295
                 +++L  G  L++ N    D G+Y+C   N VG    +  + V+ PP I       
Sbjct: 793  KDSDNLRLLPGGHGLQILNAQEEDSGQYTCVVTNEVGEAIRNYEVKVFIPPVIKRDDPHQ 852

Query: 296  NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
            ++    V  +  +     C +   P+PT+ W  +G       G+         + DG   
Sbjct: 853  DVGIKEVKTKVNSSLTLQCESQAVPKPTLHWYKDGQLLESSGGVQ-------ILSDG-QE 904

Query: 356  LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
            L +     +DS     C A N AG       + V  DD+     +T     + +    ++
Sbjct: 905  LQLQPIRLSDS-GRYTCVATNVAGEDEKEFYVNVQDDDEEE---LTE--HREVVATNPIS 958

Query: 416  VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHG 474
            ++ C     P PI+ WY +G+ L  +    +  +G ++ +       +G YTC A++  G
Sbjct: 959  LY-CDTNAIPPPILTWYKDGQLLSSSDGVLILLEGRILQIPMAHAKHAGKYTCEATNEAG 1017

Query: 475  K 475
            +
Sbjct: 1018 E 1018



 Score =  120 bits (289), Expect = 2e-25
 Identities = 122/466 (26%), Positives = 195/466 (41%), Gaps = 34/466 (7%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG-GLFFLRATHGRVHS 78
            DV V  + P +L C A G P P++ W K G       +  +LP G GL  L A       
Sbjct: 760  DVIVIVNNPFSLICEALGFPIPSVTWLKNGEPFKDSDNLRLLPGGHGLQILNAQE----E 815

Query: 79   DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK------QSAQGDTVVLECLPP 132
            D+G Y C  TN  G A  RN  + V +     R +P         ++    ++ L+C   
Sbjct: 816  DSGQYTCVVTNEVGEA-IRNYEVKVFIPPVIKRDDPHQDVGIKEVKTKVNSSLTLQC-ES 873

Query: 133  RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
            +  P+P ++W K+GQ L   G  ++ L DG  L +Q  R +D+GRY C+A N AG  E  
Sbjct: 874  QAVPKPTLHWYKDGQLLESSGGVQI-LSDGQELQLQPIRLSDSGRYTCVATNVAGEDEKE 932

Query: 193  IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL 252
                        +T   +VVA   + ++  C     P P + W +     +   G + +L
Sbjct: 933  FYVNVQDDDEEELTEHREVVAT--NPISLYCDTNAIPPPILTWYKDGQLLSSSDGVLILL 990

Query: 253  DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP----SINLSPNSVNVESGN 308
            +   L++        G+Y+CEA N  G       L V  PP     ++     V+V    
Sbjct: 991  EGRILQIPMAHAKHAGKYTCEATNEAGEDRLHYELVVLTPPVMKGEVDELIQEVSVIYNQ 1050

Query: 309  VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
             A   C A+G P P++ W +    T+     + ++Y    + +G T L I+    +D  +
Sbjct: 1051 TAELHCDASGIPPPSITW-LRNGLTL----STAERYQ--ILNEGKT-LQIHSVQVSDI-D 1101

Query: 369  TIVCSAVNYAGSS---FVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
            + VC A N AG +   F      ++    R P  +     +  L I    V  C A  +P
Sbjct: 1102 SYVCVAENPAGFAERLFTLMVHELSFSSVRCP--VPPHTRDYVLIIGKSIVLSCEAEGSP 1159

Query: 426  EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
             P++    +GE L             L +  + +S +G Y C+A +
Sbjct: 1160 SPVVTSLKDGEPLDSGVWGVAIRGSRLQITRVQQSHAGRYRCIAQN 1205



 Score =  116 bits (278), Expect = 5e-24
 Identities = 98/324 (30%), Positives = 152/324 (46%), Gaps = 25/324 (7%)

Query: 16   EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG----VLVVSDTHRSILPAGGLFF-LR 70
            E P + +V   Q   L C+  G+P+P I W+K G    V +V +T  ++    G F  LR
Sbjct: 1228 EMPSEHSVPEKQEVKLECKTEGTPAPQILWFKDGNPLDVTLVPNTSGNLTKQDGNFLVLR 1287

Query: 71   ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLEC 129
            +      SD+G Y C A N+ G   +R   L++  L    R E   + +A +G +V   C
Sbjct: 1288 SVQA---SDSGRYTCVARNNAG-EDTRVYVLNILGLPVLERSESTEEVTAIKGASVTFTC 1343

Query: 130  LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
                G+P P++ W+K+GQ L    +   + + G  L ++  R  D+G Y CIA NAAG R
Sbjct: 1344 -EAHGTPLPSLSWEKDGQPLNLQSNLLPNGL-GTRLHLESVRALDSGIYSCIAVNAAG-R 1400

Query: 190  ESAIATLKIHIKPYLITG---PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
             S    L + ++P  I G   P +V     S +   C   G P P++ W +       PL
Sbjct: 1401 VSKHFHLTV-LEPPRIEGPALPTEVSIIADSPLELACTATGVPTPEISWEKD----GRPL 1455

Query: 247  GRVKVLD-DGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSV 302
                +L  +G+ LR++ V   D G Y C A ++ G  S + ++ +  PPS+  +  P S+
Sbjct: 1456 SHPDLLTRNGTVLRIERVKAEDAGIYVCVATSTAGRDSRATWVRMKVPPSVVGSTEPRSL 1515

Query: 303  NVESGNVARFTCTATGRPEPTMFW 326
             V  G      C     P PT+ W
Sbjct: 1516 AVSVGGQLVLECKVEADPPPTIQW 1539



 Score =  104 bits (249), Expect = 2e-20
 Identities = 81/276 (29%), Positives = 131/276 (47%), Gaps = 24/276 (8%)

Query: 16   EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75
            E   +VT  +    T  C A G+P P++ W K G  +  +   ++LP G    L     R
Sbjct: 1326 ESTEEVTAIKGASVTFTCEAHGTPLPSLSWEKDGQPL--NLQSNLLPNGLGTRLHLESVR 1383

Query: 76   VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPES---KQSAQGDTVVLECLPP 132
               D+G+Y C A N+ G         H+ VL E  R+E  +   + S   D+ +      
Sbjct: 1384 A-LDSGIYSCIAVNAAGRVSKH---FHLTVL-EPPRIEGPALPTEVSIIADSPLELACTA 1438

Query: 133  RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
             G P P + W+K+G+ L       +   +G  L I+  +  DAG Y C+A + AG R+S 
Sbjct: 1439 TGVPTPEISWEKDGRPL---SHPDLLTRNGTVLRIERVKAEDAGIYVCVATSTAG-RDSR 1494

Query: 193  IATLKIHIKPYLI--TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL---G 247
               +++ + P ++  T P  +    G  +  +C+V  DP P + W R    G++PL   G
Sbjct: 1495 ATWVRMKVPPSVVGSTEPRSLAVSVGGQLVLECKVEADPPPTIQWYR----GDIPLQTDG 1550

Query: 248  RVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVS 282
            RV+VL  G  +++ ++  +D GEY+C A N  G  S
Sbjct: 1551 RVQVLSKGRYVQIHSLRPSDSGEYTCIASNPAGRTS 1586



 Score = 85.8 bits (203), Expect = 6e-15
 Identities = 82/285 (28%), Positives = 115/285 (40%), Gaps = 22/285 (7%)

Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV-LDDGS--LRLDNVILA 265
           +D+ A+ GS V   C+  G P P V W +   G  +P G   + L +G   L+L+   L+
Sbjct: 11  QDMTARDGSEVELHCKASGVPRPQVEWTKD--GQPLPPGDAHIQLTEGGQVLQLNGTRLS 68

Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES--GNVARFTCTATGRPEPT 323
           D+G Y C A N  G       L V+ PP+I  S  +  V S         C A   P P 
Sbjct: 69  DQGRYQCLAFNHAGQQVKDFNLRVHTPPTIWASNETTEVASLLHGTVELRCEARASPVPG 128

Query: 324 MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383
           + W  +  R I+    SR  Y      +G   L ++    +D   T  C A N AG++  
Sbjct: 129 ITW-FKDKRPIV--SSSRATYR-----EGGRSLQLSRVLLSDV-GTYTCRATNNAGTAEK 179

Query: 384 RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR 443
             +L V      P  +I  G  + T+         C A   P P I W     +L     
Sbjct: 180 SYRLEVYVP---PKVVIGEGSEHVTVTANDPLDLSCHATGYPTPTIQWLRNNHSLSHEDG 236

Query: 444 RNVTN---DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485
             V N      L ++    SDSG Y CVAS+  G       LLV+
Sbjct: 237 VEVLNGVQGPKLQIESAKSSDSGEYRCVASNTAGSTELQYNLLVN 281



 Score = 59.3 bits (137), Expect = 6e-07
 Identities = 63/242 (26%), Positives = 99/242 (40%), Gaps = 19/242 (7%)

Query: 292 PPSINL--SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
           PPSI    S   +    G+     C A+G P P + W+ +G    + PG +        +
Sbjct: 1   PPSIYGAGSLQDMTARDGSEVELHCKASGVPRPQVEWTKDGQP--LPPGDAH-----IQL 53

Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409
            +G  VL +N T  +D +    C A N+AG       L V +    PP I  +  + +  
Sbjct: 54  TEGGQVLQLNGTRLSD-QGRYQCLAFNHAGQQVKDFNLRVHT----PPTIWASNETTEVA 108

Query: 410 PIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTC 467
            +    V   C A  +P P I W+ +   ++ + R      G +L L  +  SD GTYTC
Sbjct: 109 SLLHGTVELRCEARASPVPGITWFKDKRPIVSSSRATYREGGRSLQLSRVLLSDVGTYTC 168

Query: 468 VASSRHGKYVWSGALLVDSPINPNIHFFRAAD-VSSLPGPPTKPITHNVTDTSVTLSWSQ 526
            A++  G    S  L V  P  P +     ++ V+     P     H     + T+ W +
Sbjct: 169 RATNNAGTAEKSYRLEVYVP--PKVVIGEGSEHVTVTANDPLDLSCHATGYPTPTIQWLR 226

Query: 527 NN 528
           NN
Sbjct: 227 NN 228


>UniRef50_Q02246 Cluster: Contactin-2 precursor; n=38;
           Euteleostomi|Rep: Contactin-2 precursor - Homo sapiens
           (Human)
          Length = 1040

 Score =  169 bits (412), Expect = 3e-40
 Identities = 140/492 (28%), Positives = 209/492 (42%), Gaps = 42/492 (8%)

Query: 12  PYIIEQPLDVTV---ARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLF 67
           P   +QPL V     +  +   L CRA  SP    RW   G  + +    R  L  G L 
Sbjct: 37  PVFEDQPLSVLFPEESTEEQVLLACRARASPPATYRWKMNGTEMKLEPGSRHQLVGGNLV 96

Query: 68  FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
            +  T  +   DAGVY C A+N  GT  SR A L    L+E  + E +  ++ +G  V+L
Sbjct: 97  IMNPTKAQ---DAGVYQCLASNPVGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVML 153

Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD--GGNLVIQDARQTDAGRYQCIARNA 185
            C PP   P  +  W  N        D R H V    GNL I     +D G Y C+A + 
Sbjct: 154 PCNPPAHYPGLSYRWLLNEFPNFIPTDGR-HFVSQTTGNLYIARTNASDLGNYSCLATSH 212

Query: 186 A--GTRE--SAIATLKIHIKPYLITGPE-------DVVAQTGSSVTFQCRVGGDPLPDVL 234
               T+   S  A L +  +   +  P        +  A  G  VT +C   G+P+P + 
Sbjct: 213 MDFSTKSVFSKFAQLNLAAEDTRLFAPSIKARFPAETYALVGQQVTLECFAFGNPVPRIK 272

Query: 235 WRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
           WR+  G     L       + +L++ +V   DEG Y CEAENS G  +  G + V   P 
Sbjct: 273 WRKVDGS----LSPQWTTAEPTLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQAQPE 328

Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
                +    + G+  R+ C A G+P PT+ W   G      P  S+++    A     +
Sbjct: 329 WLKVISDTEADIGSNLRWGCAAAGKPRPTVRWLRNGE-----PLASQNRVEVLAGDLRFS 383

Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK-- 412
            L++ D+          C A N  G+ +   +L V +      P     P  + +P    
Sbjct: 384 KLSLEDS------GMYQCVAENKHGTIYASAELAVQA----LAPDFRLNPVRRLIPAARG 433

Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
              + PC     P+ ++ W    E L+ + R  VT DGTL+++++ +SD G YTC A + 
Sbjct: 434 GEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENF 493

Query: 473 HGKYVWSGALLV 484
            GK   +G L V
Sbjct: 494 MGKANSTGILSV 505



 Score =  108 bits (259), Expect = 1e-21
 Identities = 87/309 (28%), Positives = 136/309 (44%), Gaps = 22/309 (7%)

Query: 27  QPATLNCRAGGSPSPAIRWYK--GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYW 84
           Q  TL C A G+P P I+W K  G +     T    L    + F          D G Y 
Sbjct: 255 QQVTLECFAFGNPVPRIKWRKVDGSLSPQWTTAEPTLQIPSVSF---------EDEGTYE 305

Query: 85  CEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK 144
           CEA NS G    +   +  A  + E+       ++  G  +   C    G P P V W +
Sbjct: 306 CEAENSKGRDTVQGRIIVQA--QPEWLKVISDTEADIGSNLRWGCAAA-GKPRPTVRWLR 362

Query: 145 NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL 204
           NG+ L     +R+ ++  G+L        D+G YQC+A N  GT  ++       + P  
Sbjct: 363 NGEPLA--SQNRVEVL-AGDLRFSKLSLEDSGMYQCVAENKHGTIYASAELAVQALAPDF 419

Query: 205 ITGPED--VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNV 262
              P    + A  G  +   C+    P   VLW +      +   RV V  DG+L + N+
Sbjct: 420 RLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWSKGTEI-LVNSSRVTVTPDGTLIIRNI 478

Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP-- 320
             +DEG+Y+C AEN +G  +++G L+V D   I L+P+S ++  G+     C A+  P  
Sbjct: 479 SRSDEGKYTCFAENFMGKANSTGILSVRDATKITLAPSSADINLGDNLTLQCHASHDPTM 538

Query: 321 EPTMFWSVE 329
           + T  W+++
Sbjct: 539 DLTFTWTLD 547



 Score =  107 bits (257), Expect = 2e-21
 Identities = 133/491 (27%), Positives = 192/491 (39%), Gaps = 58/491 (11%)

Query: 59  SILPAGGLFFLRATHGRVH------SDAGVYWCEATN----SYGTARSRNATLHVAVLRE 108
           + +P  G  F+  T G ++      SD G Y C AT+    S  +  S+ A L++A   E
Sbjct: 175 NFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHMDFSTKSVFSKFAQLNLAA--E 232

Query: 109 EFRLE--------PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV 160
           + RL         P    +  G  V LEC    G+P P + W+K   +L     S     
Sbjct: 233 DTRLFAPSIKARFPAETYALVGQQVTLECFA-FGNPVPRIKWRKVDGSL-----SPQWTT 286

Query: 161 DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVT 220
               L I      D G Y+C A N+ G R++    + +  +P  +    D  A  GS++ 
Sbjct: 287 AEPTLQIPSVSFEDEGTYECEAENSKG-RDTVQGRIIVQAQPEWLKVISDTEADIGSNLR 345

Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA 280
           + C   G P P V W R+ G       RV+VL  G LR   + L D G Y C AEN  G 
Sbjct: 346 WGCAAAGKPRPTVRWLRN-GEPLASQNRVEVLA-GDLRFSKLSLEDSGMYQCVAENKHGT 403

Query: 281 VSASGYLTVYD-PPSINLSP--NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337
           + AS  L V    P   L+P    +    G      C     P+  + WS     T I  
Sbjct: 404 IYASAELAVQALAPDFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWS---KGTEILV 460

Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397
             SR     T   DG   L I +  ++D      C A N+ G +   G L+V     R  
Sbjct: 461 NSSR----VTVTPDGT--LIIRNISRSDE-GKYTCFAENFMGKANSTGILSV-----RDA 508

Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL 457
             IT  PS+  + +       C A   P   + + +     + +   +    G    +  
Sbjct: 509 TKITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWT----LDDFPIDFDKPGGHYRRTN 564

Query: 458 DKSDSGTYTCV-ASSRHG-KYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNV 515
            K   G  T + A  RHG KY      +VDS         R       PGPP   +  ++
Sbjct: 565 VKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRGP-----PGPPGGVVVRDI 619

Query: 516 TDTSVTLSWSQ 526
            DT++ LSWS+
Sbjct: 620 GDTTIQLSWSR 630


>UniRef50_UPI0000F34A69 Cluster: UPI0000F34A69 related cluster; n=2;
            Bos taurus|Rep: UPI0000F34A69 UniRef100 entry - Bos
            Taurus
          Length = 4164

 Score =  168 bits (409), Expect = 7e-40
 Identities = 135/464 (29%), Positives = 207/464 (44%), Gaps = 41/464 (8%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
            DV V R     L C A GSP P + W K G  ++    +S+    GL    A  G     
Sbjct: 3276 DVAVVRGSLVFLPCEARGSPLPFVSWVKDGEPLLP---QSLEHGPGLLLEAAEAGH---- 3328

Query: 80   AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
            AG Y C A +  G AR       +     E   +PE      G  + L C   RG+P PN
Sbjct: 3329 AGTYSCVAVSEAGEARRHFQLTVMDPPYIEDSDQPEELLLTPGTPLELLC-DARGTPTPN 3387

Query: 140  VYWKKNGQTLLFDGDSRMHLVDGGNLV--IQDARQTDAGRYQCIARNAAGTRESAIATLK 197
            + W K+G+ L +  D +     G   V  ++  + +DAG Y C+A + AG  E +   ++
Sbjct: 3388 ITWHKDGRALSWPEDGQ-----GARRVLRVEGVQVSDAGLYTCLAHSPAGEVEKSFR-IR 3441

Query: 198  IHIKPYLIT--GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
            +   P +I   GP  VV      +  +C V  DP P++ W R  G         +  ++G
Sbjct: 3442 VQAPPNVIGSHGPRFVVGLAPGQLVLECSVEADPAPEIEWHRE-GVLLQADAHTQFPEEG 3500

Query: 256  S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
              L+L  +  AD G+YSC A N+ G+ S + ++ V+ PP++N S N   +         C
Sbjct: 3501 RFLQLQALSTADSGDYSCTAHNAAGSTSLAFHVEVHRPPTVNASVNQTTL-------LPC 3553

Query: 315  TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
             A G P+P + W  +G    + PG +R       + +G+ +  +   D        +C A
Sbjct: 3554 QADGVPQPLVSWLKDG--VPLDPGSTRWVLAREGLREGLRIQPVLAEDAGH----YLCLA 3607

Query: 375  VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFE 434
             N AGS      L V       PP I  GPSN TL   + A  PC A  +P+P++AW+ +
Sbjct: 3608 SNPAGSDRQGRDLQVFE-----PPAIAPGPSNLTLTAYTPASLPCEASGSPKPLVAWWKD 3662

Query: 435  GEAL---IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
            G+ L   +Q     +     L+L++    DS  + CV S+  G+
Sbjct: 3663 GQKLDFRLQQGAYRLLPSNALLLEEPSPQDSALFECVVSNGVGE 3706



 Score =  165 bits (401), Expect = 6e-39
 Identities = 138/474 (29%), Positives = 201/474 (42%), Gaps = 33/474 (6%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV---VSDTHRSILPAGGL 66
            E P I   P ++T+  + PA+L C A GSP P + W+K G  +   +      +LP+  L
Sbjct: 3624 EPPAIAPGPSNLTLTAYTPASLPCEASGSPKPLVAWWKDGQKLDFRLQQGAYRLLPSNAL 3683

Query: 67   FFLRATHGRVHSDAGVYWCEATNSYGTARSRN-ATLHVAVLREEFRLEPESKQSAQGDTV 125
                 +      D+ ++ C  +N  G AR     T+HV     + + +  +   A    V
Sbjct: 3684 LLEEPSP----QDSALFECVVSNGVGEARKLYWVTVHVPPAIADDQTDFTATIMAP---V 3736

Query: 126  VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
            VL C    G P P V W K G  L   G+    +   G L I  A     GRY C ARNA
Sbjct: 3737 VLTC-HSTGVPAPVVSWSKAGTRLGVRGNG-YRVSPSGALEIGQALPIHTGRYTCAARNA 3794

Query: 186  AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR---SAGGG 242
            AG     +  L +   P +   P  V A     V   C   G P P + W++   S    
Sbjct: 3795 AGMAHKHVV-LTVQASPVVKPLPSVVWAVAKEEVLLPCEASGIPRPSIAWQKEGLSVPAA 3853

Query: 243  NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
            N   G  +VL  G LR+ +V   D G Y C A+NS G+      L V  PP+I      +
Sbjct: 3854 NPGAG-TQVLPGGQLRIIHVSPEDAGNYFCLAQNSAGSAVRKTRLVVQVPPAIKTGLPDL 3912

Query: 303  NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
            ++  G  A   CTATG PEP + W  +G        +S  K   T    G   L + +++
Sbjct: 3913 SITEGAHALLPCTATGSPEPKVTWEKDGQP------VSGAKGKFTIQPSGE--LLVKNSE 3964

Query: 363  KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
              D+  T  C+A N  G +  R  LT+ +      P+ T  P +++L +       C A 
Sbjct: 3965 SQDA-GTYTCTAENAVGRARRRVHLTILA-----LPVFTTLPGDRSLRLGDKLWLHCAAR 4018

Query: 423  CTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGK 475
             +P P I W      +      +  + G TL    + + DSGTY C A +R G+
Sbjct: 4019 GSPTPQIGWTVNNRLVTATEGVSEQDGGSTLQRVAVTREDSGTYVCWAENRVGR 4072



 Score =  161 bits (392), Expect = 8e-38
 Identities = 139/458 (30%), Positives = 204/458 (44%), Gaps = 31/458 (6%)

Query: 27   QPATLNCRAGGSPSPAIRWYKGGVLVVS-DTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85
            Q  TL C A G P+P I W K G  + +  +HR +  A  L F R   G    D+G+Y C
Sbjct: 1156 QSLTLECDANGFPAPEITWLKNGRQIPAVGSHRLLDGARALHFPRIQEG----DSGLYSC 1211

Query: 86   EATNSYGTARSRNATLHVAVLREEFRLEPESKQ-SAQGDTVVLECLPPRGSPEPNVYWKK 144
             A N  GTA+ R+  L V +       E   +     G    LEC    G P P V W K
Sbjct: 1212 RAENQAGTAQ-RDFDLLVLIPPSVLGAEAAQEVVGLAGAGAELECRT-LGVPTPQVEWTK 1269

Query: 145  NGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY 203
            +GQ + F G+ R+ L + G ++ I ++   D G YQC+A + AG +++    L+IH  P 
Sbjct: 1270 DGQPV-FLGEPRVQLQEDGQVLRITNSHLGDEGWYQCVAFSPAG-QQTKDFQLRIHAPPT 1327

Query: 204  LITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG-SLRLD 260
            +    E  +V    G  V F C   G P PD+ W +  G   +P   V     G  L+L+
Sbjct: 1328 IWGSNETSEVAVMEGHPVWFLCEARGVPTPDITWFKD-GDPLVPSTEVVYTRGGRQLQLE 1386

Query: 261  NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI---NLSPNSVNVESGNVARFTCTAT 317
                +D G YSC+A N+VG V  +  L VY PP+I      P  V   +G      C A 
Sbjct: 1387 RAQGSDAGTYSCKASNAVGVVEKTTRLEVYVPPTIEGTGEGPRVVKAVAGRPLTLECVAR 1446

Query: 318  GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
            G P PT+ W  EG      P + R   + T +  G  VL++    +  S     C A + 
Sbjct: 1447 GYPPPTVSWYHEG-----LPVVDR---NGTWLGAGGGVLSLESLGE-ASGGLYSCVASSP 1497

Query: 378  AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437
            AG + +   + V      P  ++  G    T  +      PC A  +P P I W   G  
Sbjct: 1498 AGEAVLHYSVEV---QVAPQLLVAEGLGQVTTLVGQSLYLPCYASGSPVPTIQWLQNGHP 1554

Query: 438  LIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
              +    +VT++G TL +  ++   +G + C A++  G
Sbjct: 1555 AEELPGVHVTSEGTTLHIDHVELGHAGLFACQATNEAG 1592



 Score =  159 bits (387), Expect = 3e-37
 Identities = 145/472 (30%), Positives = 202/472 (42%), Gaps = 29/472 (6%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
           V +G  P ++  P +VTV+  + A L+C         + W +   ++ + T R    A  
Sbjct: 483 VVTGPPPQLVPVP-NVTVSPGETAILSCLVLSEAPYNLTWVRDWRVLSASTGRVTQLADL 541

Query: 66  LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDT 124
              +R T     SD G Y C A+NS G  R   A++ + V    +  +   S++ +QG  
Sbjct: 542 SLEVRNT---TPSDGGRYQCMASNSNGVTR---ASVWLLVREAPQVSIHTRSQRFSQGME 595

Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
           V + C    G P P++ W + G+ L    DSR+ +   G L+IQ     DAG Y C A N
Sbjct: 596 VRVRC-SASGYPAPHISWSREGRAL--QEDSRVRVDAQGTLIIQGVAPEDAGSYSCQAAN 652

Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
             G  E  + TL     P +      V+A  G     +C   G P P V+W R  G   M
Sbjct: 653 EIGRDEETV-TLYYTDPPSVSAVNGVVLAAKGEEAVLECEATGVPPPRVIWYR--GDLEM 709

Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
            L     +  G LR+  V   D G Y+C A N +G  SA   L V   P +   P  V V
Sbjct: 710 ILAPEDSIS-GMLRIPVVRERDAGVYTCRAVNELGDASAEIRLEVGHAPQLLELPQDVTV 768

Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
           E G  A   C ATG P PT+ W    ++ +   G SR    A    DG   L   D    
Sbjct: 769 ELGRSALLACRATGHPLPTITWHRGDDQPLGLRG-SRHSIRA----DGSLHL---DQALL 820

Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTV-TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
           +      C   N AGS     +L V      R  P  T+  +N+ +P    A  PC A  
Sbjct: 821 EDAGRYSCVVSNTAGSHHRDVQLVVQVKVPPRIQPTATHHITNEGVP----ASLPCVASG 876

Query: 424 TPEPIIAWYFEGEALI-QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
            P P I W  E  AL  ++   NV+ DGTLV+      D+G Y C A++  G
Sbjct: 877 VPTPTITWTKETNALASRDPHYNVSKDGTLVIPRPSVQDAGAYVCTATNAVG 928



 Score =  159 bits (387), Expect = 3e-37
 Identities = 144/501 (28%), Positives = 203/501 (40%), Gaps = 47/501 (9%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            EAP +         ++     + C A G P+P I W + G  +  D+   +   G L   
Sbjct: 577  EAPQVSIHTRSQRFSQGMEVRVRCSASGYPAPHISWSREGRALQEDSRVRVDAQGTLII- 635

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
                G    DAG Y C+A N  G       TL+         +      +A+G+  VLEC
Sbjct: 636  ---QGVAPEDAGSYSCQAANEIGRDEE-TVTLYYTDPPSVSAVNGVVL-AAKGEEAVLEC 690

Query: 130  LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
                G P P V W +    ++   +  +     G L I   R+ DAG Y C A N  G  
Sbjct: 691  -EATGVPPPRVIWYRGDLEMILAPEDSI----SGMLRIPVVRERDAGVYTCRAVNELGDA 745

Query: 190  ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-- 247
             + I  L++   P L+  P+DV  + G S    CR  G PLP + W R   G + PLG  
Sbjct: 746  SAEIR-LEVGHAPQLLELPQDVTVELGRSALLACRATGHPLPTITWHR---GDDQPLGLR 801

Query: 248  --RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PPSINLSPNSVN 303
              R  +  DGSL LD  +L D G YSC   N+ G+      L V    PP I  +     
Sbjct: 802  GSRHSIRADGSLHLDQALLEDAGRYSCVVSNTAGSHHRDVQLVVQVKVPPRIQPTATHHI 861

Query: 304  VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
               G  A   C A+G P PT+ W+ E N        SRD ++  +  DG   L I     
Sbjct: 862  TNEGVPASLPCVASGVPTPTITWTKETNALA-----SRDPHYNVSK-DGT--LVIPRPSV 913

Query: 364  NDSRNTIVCSAVNYAGSSFVRGKLTVTSD-----DDR-----PPPIITNGPSNQTLPIKS 413
             D+    VC+A N  G S    +L+V  +     D +      P I+ NG      P++ 
Sbjct: 914  QDA-GAYVCTATNAVGFSSQEMRLSVNMEPGFLLDPKHGATAKPRILVNGSHEADKPLRV 972

Query: 414  MA------VFPCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDLDKSDSGTYT 466
             A         C A  +P P++ W  +   ++    R ++   G+L L     SDSG Y 
Sbjct: 973  TAKAGDEVTLDCEAQGSPPPLVTWTKDSRHMLPITDRHHLLPPGSLHLAQAQVSDSGLYE 1032

Query: 467  CVASSRHGKYVWSGALLVDSP 487
            C AS+  G       L V  P
Sbjct: 1033 CTASNPAGSATQYYILRVQVP 1053



 Score =  158 bits (383), Expect = 1e-36
 Identities = 133/457 (29%), Positives = 199/457 (43%), Gaps = 34/457 (7%)

Query: 23   VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
            +  + PA L C     P+  + WY+G   +  +   S+L  G +  +         DAG 
Sbjct: 2633 IVENNPAYLYCDTNAVPAAELTWYRGDRPLSIEDGVSVLQGGRVLQIPLVRAE---DAGR 2689

Query: 83   YWCEATNSYGTARSRNATLHVA---VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
            Y C+A+N  G        L +    +L E   L  E   +A   TV L C P  G+P P 
Sbjct: 2690 YSCKASNEVGEDWLHYELLVLTPPVILGETEELVEEVTVNANS-TVSLHC-PVLGNPAPT 2747

Query: 140  VYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
            + W +NG  L F    R+ +++ G ++ +  A   DA  Y C+A N AG+ E  + TL++
Sbjct: 2748 ISWLQNG--LPFSPSPRLQVLENGRILQVSTAEVADAASYMCVAENPAGSTEK-LFTLRV 2804

Query: 199  HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-- 256
              +P L   PE + A   SSV+  C V   P P+V W +   G  + LG    L  G+  
Sbjct: 2805 QGEPGL--NPEQITATLNSSVSLPCDVRAHPSPEVTWYKD--GWTLSLGEEIFLLPGTHT 2860

Query: 257  LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316
            L+L  V L D G Y CEA N+ G       L+V  P + +   + V V +G+ A  +C  
Sbjct: 2861 LQLTRVQLLDSGMYICEALNAAGRDHKLVQLSVLAPGAPSRPQDVVLVSAGDKAVLSCET 2920

Query: 317  TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
               PEPT+ W  +G + ++ P    ++  A     G   L I D   +D +    C   N
Sbjct: 2921 DAFPEPTVAWQKDG-QPLVLP----ERIQALL---GGQRLEIQDAQVSD-KGLYSCRVSN 2971

Query: 377  YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK-SMAVFPCTAICTPEPIIAWYFEG 435
             AG +     LTV     + PP   N  +     +  S  V  C     P P + W  + 
Sbjct: 2972 AAGEAMRAFSLTV-----QVPPTFENPETEMVSRVAGSPLVLSCDVTGVPAPAVTWLKDR 3026

Query: 436  EALIQNHRRN-VTNDGTLVLKDLDKSDSGTYTCVASS 471
              +  +  R  V+  G L L  L    +GTYTCVA +
Sbjct: 3027 MPVESSMARGVVSRGGRLQLSHLQPDQAGTYTCVAEN 3063



 Score =  157 bits (382), Expect = 1e-36
 Identities = 127/472 (26%), Positives = 193/472 (40%), Gaps = 24/472 (5%)

Query: 5    YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPA 63
            +VT    P I +   D T     P  L C + G P+P + W K G  L V      + P+
Sbjct: 3712 WVTVHVPPAIADDQTDFTATIMAPVVLTCHSTGVPAPVVSWSKAGTRLGVRGNGYRVSPS 3771

Query: 64   GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
            G L   +A    +H+  G Y C A N+ G A  ++  L V        L P    +   +
Sbjct: 3772 GALEIGQALP--IHT--GRYTCAARNAAGMAH-KHVVLTVQASPVVKPL-PSVVWAVAKE 3825

Query: 124  TVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
             V+L C    G P P++ W+K G ++   +  +   ++ GG L I      DAG Y C+A
Sbjct: 3826 EVLLPC-EASGIPRPSIAWQKEGLSVPAANPGAGTQVLPGGQLRIIHVSPEDAGNYFCLA 3884

Query: 183  RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
            +N+AG+       L + + P + TG  D+    G+     C   G P P V W +     
Sbjct: 3885 QNSAGSAVRK-TRLVVQVPPAIKTGLPDLSITEGAHALLPCTATGSPEPKVTWEKDGQPV 3943

Query: 243  NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
            +   G+  +   G L + N    D G Y+C AEN+VG      +LT+   P     P   
Sbjct: 3944 SGAKGKFTIQPSGELLVKNSESQDAGTYTCTAENAVGRARRRVHLTILALPVFTTLPGDR 4003

Query: 303  NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
            ++  G+     C A G P P + W+V         G+S          DG + L      
Sbjct: 4004 SLRLGDKLWLHCAARGSPTPQIGWTVNNRLVTATEGVSEQ--------DGGSTLQRVAVT 4055

Query: 363  KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
            + DS  T VC A N  G         V+    +  P+    P + T+         C A 
Sbjct: 4056 REDS-GTYVCWAENRVGR-----VQAVSFVHVKGVPVFQVKPQDVTVRSGDSVALRCQAS 4109

Query: 423  CTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
              P P + W   G+ +  + R     DG+L L+ ++  D+G Y CVA +  G
Sbjct: 4110 GEPAPTMEWLRAGQPVRASQRLQTLPDGSLWLERVEARDAGPYECVAHNLLG 4161



 Score =  157 bits (380), Expect = 2e-36
 Identities = 139/469 (29%), Positives = 216/469 (46%), Gaps = 40/469 (8%)

Query: 16   EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG--VLVVSDTHRSILPAGGLFFLRATH 73
            ++PL VT       TL+C A GSP P + W K    +L ++D H  +LP G L   +A  
Sbjct: 967  DKPLRVTAKAGDEVTLDCEAQGSPPPLVTWTKDSRHMLPITDRHH-LLPPGSLHLAQAQ- 1024

Query: 74   GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
                SD+G+Y C A+N  G+A ++   L V V   + +  P   +   G+ V L C+   
Sbjct: 1025 ---VSDSGLYECTASNPAGSA-TQYYILRVQV-PPQVQPGPRVLKVLVGEAVDLNCV-AE 1078

Query: 134  GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
            GSPEP V W K+G  L  +G         G++     + + AG Y+C A ++AG  ++  
Sbjct: 1079 GSPEPRVTWSKDGVALRGEGPE-------GSVHFAAIQTSHAGTYRCEASSSAGV-DAWE 1130

Query: 194  ATLKIHIKPYLITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP-LGRVK 250
              L++ + P L       +V    G S+T +C   G P P++ W ++  G  +P +G  +
Sbjct: 1131 LDLRVLVPPSLREDGRRANVSGMAGQSLTLECDANGFPAPEITWLKN--GRQIPAVGSHR 1188

Query: 251  VLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE--SG 307
            +LD   +L    +   D G YSC AEN  G       L V  PPS+  +  +  V   +G
Sbjct: 1189 LLDGARALHFPRIQEGDSGLYSCRAENQAGTAQRDFDLLVLIPPSVLGAEAAQEVVGLAG 1248

Query: 308  NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
              A   C   G P P + W+ +G    +F G  R +       DG  VL I ++   D  
Sbjct: 1249 AGAELECRTLGVPTPQVEWTKDGQP--VFLGEPRVQLQE----DG-QVLRITNSHLGD-E 1300

Query: 368  NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPE 426
                C A + AG      +L + +    PP I  +  +++   ++   V F C A   P 
Sbjct: 1301 GWYQCVAFSPAGQQTKDFQLRIHA----PPTIWGSNETSEVAVMEGHPVWFLCEARGVPT 1356

Query: 427  PIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
            P I W+ +G+ L+ +     T  G  L L+    SD+GTY+C AS+  G
Sbjct: 1357 PDITWFKDGDPLVPSTEVVYTRGGRQLQLERAQGSDAGTYSCKASNAVG 1405



 Score =  156 bits (378), Expect = 4e-36
 Identities = 122/463 (26%), Positives = 196/463 (42%), Gaps = 18/463 (3%)

Query: 15   IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74
            + +P  V  + +Q   L C+A G P P + W K GV +   + R +L   GL        
Sbjct: 3535 VHRPPTVNASVNQTTLLPCQADGVPQPLVSWLKDGVPLDPGSTRWVLAREGLREGLRIQP 3594

Query: 75   RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRG 134
             +  DAG Y C A+N  G+ R +   L V          P +          L C    G
Sbjct: 3595 VLAEDAGHYLCLASNPAGSDR-QGRDLQVFE-PPAIAPGPSNLTLTAYTPASLPC-EASG 3651

Query: 135  SPEPNVYWKKNGQTLLFD-GDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
            SP+P V W K+GQ L F        L+    L++++    D+  ++C+  N  G     +
Sbjct: 3652 SPKPLVAWWKDGQKLDFRLQQGAYRLLPSNALLLEEPSPQDSALFECVVSNGVGEARK-L 3710

Query: 194  ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD 253
              + +H+ P +     D  A   + V   C   G P P V W ++     +     +V  
Sbjct: 3711 YWVTVHVPPAIADDQTDFTATIMAPVVLTCHSTGVPAPVVSWSKAGTRLGVRGNGYRVSP 3770

Query: 254  DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313
             G+L +   +    G Y+C A N+ G       LTV   P +   P+ V   +       
Sbjct: 3771 SGALEIGQALPIHTGRYTCAARNAAGMAHKHVVLTVQASPVVKPLPSVVWAVAKEEVLLP 3830

Query: 314  CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
            C A+G P P++ W  EG   +  P  +      T V  G  +  I+     D+ N   C 
Sbjct: 3831 CEASGIPRPSIAWQKEG---LSVPAANPGA--GTQVLPGGQLRIIH-VSPEDAGNYF-CL 3883

Query: 374  AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF 433
            A N AGS+  + +L V     + PP I  G  + ++   + A+ PCTA  +PEP + W  
Sbjct: 3884 AQNSAGSAVRKTRLVV-----QVPPAIKTGLPDLSITEGAHALLPCTATGSPEPKVTWEK 3938

Query: 434  EGEALI-QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
            +G+ +     +  +   G L++K+ +  D+GTYTC A +  G+
Sbjct: 3939 DGQPVSGAKGKFTIQPSGELLVKNSESQDAGTYTCTAENAVGR 3981



 Score =  154 bits (373), Expect = 2e-35
 Identities = 145/480 (30%), Positives = 209/480 (43%), Gaps = 45/480 (9%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P +   P  + V   +   LNC A GSP P + W K GV +     R   P G + F   
Sbjct: 1054 PQVQPGPRVLKVLVGEAVDLNCVAEGSPEPRVTWSKDGVAL-----RGEGPEGSVHFAAI 1108

Query: 72   THGRVHSDAGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEPESKQSAQGDTVVLE 128
                  S AG Y CEA++S G   +    L V V   LRE+ R    S  +  G ++ LE
Sbjct: 1109 Q----TSHAGTYRCEASSSAG-VDAWELDLRVLVPPSLREDGRRANVSGMA--GQSLTLE 1161

Query: 129  CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAG 187
            C    G P P + W KNG+ +   G  R  L+DG   L     ++ D+G Y C A N AG
Sbjct: 1162 C-DANGFPAPEITWLKNGRQIPAVGSHR--LLDGARALHFPRIQEGDSGLYSCRAENQAG 1218

Query: 188  TRESAIATLKIHIKPYLI--TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
            T +     L + I P ++     ++VV   G+    +CR  G P P V W +      + 
Sbjct: 1219 TAQRDF-DLLVLIPPSVLGAEAAQEVVGLAGAGAELECRTLGVPTPQVEWTKDGQPVFLG 1277

Query: 246  LGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSV 302
              RV++ +DG  LR+ N  L DEG Y C A +  G  +    L ++ PP+I  +   + V
Sbjct: 1278 EPRVQLQEDGQVLRITNSHLGDEGWYQCVAFSPAGQQTKDFQLRIHAPPTIWGSNETSEV 1337

Query: 303  NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
             V  G+   F C A G P P + W  +G+  +  P              G   L +    
Sbjct: 1338 AVMEGHPVWFLCEARGVPTPDITWFKDGDPLV--PSTE------VVYTRGGRQLQLERAQ 1389

Query: 363  KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
             +D+  T  C A N  G      +L V      PP I   G   +   +K++A  P T  
Sbjct: 1390 GSDA-GTYSCKASNAVGVVEKTTRLEVYV----PPTIEGTGEGPRV--VKAVAGRPLTLE 1442

Query: 423  CT----PEPIIAWYFEGEALI-QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
            C     P P ++WY EG  ++ +N        G L L+ L ++  G Y+CVASS  G+ V
Sbjct: 1443 CVARGYPPPTVSWYHEGLPVVDRNGTWLGAGGGVLSLESLGEASGGLYSCVASSPAGEAV 1502



 Score =  152 bits (368), Expect = 6e-35
 Identities = 139/490 (28%), Positives = 209/490 (42%), Gaps = 37/490 (7%)

Query: 10   EAPYIIEQPLDVTVAR--HQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
            + P   E P    V+R    P  L+C   G P+PA+ W K  + V S   R ++  GG  
Sbjct: 2985 QVPPTFENPETEMVSRVAGSPLVLSCDVTGVPAPAVTWLKDRMPVESSMARGVVSRGGR- 3043

Query: 68   FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
             L+ +H +    AG Y C A N+   A        +   R +     +     +G  V L
Sbjct: 3044 -LQLSHLQP-DQAGTYTCVAENAQAEAHKDFVVAVLVAPRIQSSGTTQEHSVLEGQDVQL 3101

Query: 128  ECLPPRGSPEPNVYWKKNGQTLLFD-GDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
            +C    G P P V W K+G  L    G      ++G +LV++D R +D+G Y C+ARNAA
Sbjct: 3102 DC-EVDGQPPPYVVWLKDGSPLDESVGPYLWFYLNGSSLVLKDLRASDSGAYTCVARNAA 3160

Query: 187  GTRESAIATLKIHIKPYLITGPE---DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
            G  ++ + T+ + + P +  GPE    +V + G  V+  C V G P   V W +   G  
Sbjct: 3161 G-EDAKLYTVNVLVPPTIEQGPEGAGTLVHRLGDLVSMACPVRGSPPIHVSWLKD--GLP 3217

Query: 244  MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS--PNS 301
            +PL     L      L  V LAD G ++C A +  G  +    L V  PP +  +   N 
Sbjct: 3218 LPLSHRTHLHSSGRTL-RVQLADSGTFTCVAASPAGVANRHFILQVLVPPVLEPAEFQND 3276

Query: 302  VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
            V V  G++    C A G P P + W  +G      P + +   H   +        + + 
Sbjct: 3277 VAVVRGSLVFLPCEARGSPLPFVSWVKDGE-----PLLPQSLEHGPGL--------LLEA 3323

Query: 362  DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII--TNGPSNQTLPIKSMAVFPC 419
             +     T  C AV+ AG +    +LTV       PP I  ++ P    L   +     C
Sbjct: 3324 AEAGHAGTYSCVAVSEAGEARRHFQLTVMD-----PPYIEDSDQPEELLLTPGTPLELLC 3378

Query: 420  TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479
             A  TP P I W+ +G AL             L ++ +  SD+G YTC+A S  G+   S
Sbjct: 3379 DARGTPTPNITWHKDGRALSWPEDGQGAR-RVLRVEGVQVSDAGLYTCLAHSPAGEVEKS 3437

Query: 480  GALLVDSPIN 489
              + V +P N
Sbjct: 3438 FRIRVQAPPN 3447



 Score =  142 bits (344), Expect = 5e-32
 Identities = 131/464 (28%), Positives = 196/464 (42%), Gaps = 30/464 (6%)

Query: 18   PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
            P  +T   +   +L C     PSP + WYK G  +       +LP  G   L+ T  ++ 
Sbjct: 2812 PEQITATLNSSVSLPCDVRAHPSPEVTWYKDGWTLSLGEEIFLLP--GTHTLQLTRVQL- 2868

Query: 78   SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDTVVLECLPPRGSP 136
             D+G+Y CEA N+ G        + ++VL       P+       GD  VL C      P
Sbjct: 2869 LDSGMYICEALNAAGRDHK---LVQLSVLAPGAPSRPQDVVLVSAGDKAVLSC-ETDAFP 2924

Query: 137  EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
            EP V W+K+GQ L+   +    L+ G  L IQDA+ +D G Y C   NAAG    A + L
Sbjct: 2925 EPTVAWQKDGQPLVLP-ERIQALLGGQRLEIQDAQVSDKGLYSCRVSNAAGEAMRAFS-L 2982

Query: 197  KIHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
             + + P       ++V++  GS +   C V G P P V W +        + R  V   G
Sbjct: 2983 TVQVPPTFENPETEMVSRVAGSPLVLSCDVTGVPAPAVTWLKDRMPVESSMARGVVSRGG 3042

Query: 256  SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV--NVESGNVARFT 313
             L+L ++     G Y+C AEN+         + V   P I  S  +   +V  G   +  
Sbjct: 3043 RLQLSHLQPDQAGTYTCVAENAQAEAHKDFVVAVLVAPRIQSSGTTQEHSVLEGQDVQLD 3102

Query: 314  CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
            C   G+P P + W  +G+      G     Y      +G + L + D   +DS     C 
Sbjct: 3103 CEVDGQPPPYVVWLKDGSPLDESVGPYLWFY-----LNGSS-LVLKDLRASDS-GAYTCV 3155

Query: 374  AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ-TLP--IKSMAVFPCTAICTPEPIIA 430
            A N AG       + V       PP I  GP    TL   +  +    C    +P   ++
Sbjct: 3156 ARNAAGEDAKLYTVNVLV-----PPTIEQGPEGAGTLVHRLGDLVSMACPVRGSPPIHVS 3210

Query: 431  WYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
            W  +G  L  +HR ++ + G  +   L  +DSGT+TCVA+S  G
Sbjct: 3211 WLKDGLPLPLSHRTHLHSSGRTLRVQL--ADSGTFTCVAASPAG 3252



 Score =  141 bits (341), Expect = 1e-31
 Identities = 134/477 (28%), Positives = 205/477 (42%), Gaps = 35/477 (7%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
            V  GE   ++E+   VTV  +   +L+C   G+P+P I W + G+         +L  G 
Sbjct: 2714 VILGETEELVEE---VTVNANSTVSLHCPVLGNPAPTISWLQNGLPFSPSPRLQVLENGR 2770

Query: 66   LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
            +  L+ +   V +DA  Y C A N  G+   +  TL V   + E  L PE   +    +V
Sbjct: 2771 I--LQVSTAEV-ADAASYMCVAENPAGST-EKLFTLRV---QGEPGLNPEQITATLNSSV 2823

Query: 126  VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
             L C   R  P P V W K+G TL   G+    L     L +   +  D+G Y C A NA
Sbjct: 2824 SLPC-DVRAHPSPEVTWYKDGWTLSL-GEEIFLLPGTHTLQLTRVQLLDSGMYICEALNA 2881

Query: 186  AGTRESAIATLKIHIKPYLITGPEDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
            AG R+  +  L + + P   + P+DVV    G      C     P P V W++      +
Sbjct: 2882 AG-RDHKLVQLSV-LAPGAPSRPQDVVLVSAGDKAVLSCETDAFPEPTVAWQKDGQPLVL 2939

Query: 245  PLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-NLSPNSV 302
            P  R++ L  G  L + +  ++D+G YSC   N+ G    +  LTV  PP+  N     V
Sbjct: 2940 P-ERIQALLGGQRLEIQDAQVSDKGLYSCRVSNAAGEAMRAFSLTVQVPPTFENPETEMV 2998

Query: 303  NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
            +  +G+    +C  TG P P + W  +  R  +   M+R          G   L+    D
Sbjct: 2999 SRVAGSPLVLSCDVTGVPAPAVTWLKD--RMPVESSMAR----GVVSRGGRLQLSHLQPD 3052

Query: 363  KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTA 421
            +  +   +  +A   A   FV   L         P I ++G + +   ++   V   C  
Sbjct: 3053 QAGTYTCVAENAQAEAHKDFVVAVLVA-------PRIQSSGTTQEHSVLEGQDVQLDCEV 3105

Query: 422  ICTPEPIIAWYFEGEALIQN---HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
               P P + W  +G  L ++   +     N  +LVLKDL  SDSG YTCVA +  G+
Sbjct: 3106 DGQPPPYVVWLKDGSPLDESVGPYLWFYLNGSSLVLKDLRASDSGAYTCVARNAAGE 3162



 Score =  140 bits (340), Expect = 2e-31
 Identities = 130/465 (27%), Positives = 186/465 (40%), Gaps = 37/465 (7%)

Query: 31   LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
            L C     P+P I W++ GVL+ +D H      G    L+A      +D+G Y C A N+
Sbjct: 3467 LECSVEADPAPEIEWHREGVLLQADAHTQFPEEGRFLQLQALST---ADSGDYSCTAHNA 3523

Query: 91   YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
             G   S +   HV V R      P +  ++   T +L C    G P+P V W K+G  L 
Sbjct: 3524 AG---STSLAFHVEVHR------PPTVNASVNQTTLLPCQAD-GVPQPLVSWLKDGVPL- 3572

Query: 151  FDGDSRMHLVDGG---NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG 207
              G +R  L   G    L IQ     DAG Y C+A N AG+       L++   P +  G
Sbjct: 3573 DPGSTRWVLAREGLREGLRIQPVLAEDAGHYLCLASNPAGSDRQG-RDLQVFEPPAIAPG 3631

Query: 208  PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL--GRVKVLDDGSLRLDNVILA 265
            P ++     +  +  C   G P P V W +     +  L  G  ++L   +L L+     
Sbjct: 3632 PSNLTLTAYTPASLPCEASGSPKPLVAWWKDGQKLDFRLQQGAYRLLPSNALLLEEPSPQ 3691

Query: 266  DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325
            D   + C   N VG      ++TV+ PP+I                 TC +TG P P + 
Sbjct: 3692 DSALFECVVSNGVGEARKLYWVTVHVPPAIADDQTDFTATIMAPVVLTCHSTGVPAPVVS 3751

Query: 326  WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385
            WS  G R     G+  + Y  +    G   +       +  R T  C+A N AG +    
Sbjct: 3752 WSKAGTRL----GVRGNGYRVSP--SGALEIG-QALPIHTGRYT--CAARNAAGMAHKHV 3802

Query: 386  KLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG---EALIQNH 442
             LTV +      P++   PS      K   + PC A   P P IAW  EG    A     
Sbjct: 3803 VLTVQAS-----PVVKPLPSVVWAVAKEEVLLPCEASGIPRPSIAWQKEGLSVPAANPGA 3857

Query: 443  RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
               V   G L +  +   D+G Y C+A +  G  V    L+V  P
Sbjct: 3858 GTQVLPGGQLRIIHVSPEDAGNYFCLAQNSAGSAVRKTRLVVQVP 3902



 Score =  136 bits (330), Expect = 3e-30
 Identities = 137/489 (28%), Positives = 203/489 (41%), Gaps = 59/489 (12%)

Query: 28   PATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
            PA+L C A G P+P I W K    L   D H ++   G L   R +      DAG Y C 
Sbjct: 867  PASLPCVASGVPTPTITWTKETNALASRDPHYNVSKDGTLVIPRPSV----QDAGAYVCT 922

Query: 87   ATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---------------------GDTV 125
            ATN+ G + S+   L V  +   F L+P+   +A+                     GD V
Sbjct: 923  ATNAVGFS-SQEMRLSVN-MEPGFLLDPKHGATAKPRILVNGSHEADKPLRVTAKAGDEV 980

Query: 126  VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
             L+C   +GSP P V W K+ + +L   D R HL+  G+L +  A+ +D+G Y+C A N 
Sbjct: 981  TLDC-EAQGSPPPLVTWTKDSRHMLPITD-RHHLLPPGSLHLAQAQVSDSGLYECTASNP 1038

Query: 186  AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS--AGGGN 243
            AG+  +    L++ + P +  GP  +    G +V   C   G P P V W +   A  G 
Sbjct: 1039 AGSA-TQYYILRVQVPPQVQPGPRVLKVLVGEAVDLNCVAEGSPEPRVTWSKDGVALRGE 1097

Query: 244  MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
             P        +GS+    +  +  G Y CEA +S G  +    L V  PPS+       N
Sbjct: 1098 GP--------EGSVHFAAIQTSHAGTYRCEASSSAGVDAWELDLRVLVPPSLREDGRRAN 1149

Query: 304  VE--SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
            V   +G      C A G P P + W   G R I   G  R       + DG   L     
Sbjct: 1150 VSGMAGQSLTLECDANGFPAPEITWLKNG-RQIPAVGSHR-------LLDGARALHFPRI 1201

Query: 362  DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM-AVFPCT 420
             + DS     C A N AG++     L V      PP ++    + + + +    A   C 
Sbjct: 1202 QEGDS-GLYSCRAENQAGTAQRDFDLLVLI----PPSVLGAEAAQEVVGLAGAGAELECR 1256

Query: 421  AICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLV-LKDLDKSDSGTYTCVASSRHGKYVW 478
             +  P P + W  +G+ +     R  +  DG ++ + +    D G Y CVA S  G+   
Sbjct: 1257 TLGVPTPQVEWTKDGQPVFLGEPRVQLQEDGQVLRITNSHLGDEGWYQCVAFSPAGQQTK 1316

Query: 479  SGALLVDSP 487
               L + +P
Sbjct: 1317 DFQLRIHAP 1325



 Score =  134 bits (324), Expect = 1e-29
 Identities = 125/453 (27%), Positives = 191/453 (42%), Gaps = 32/453 (7%)

Query: 29   ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
            A L CR  G P+P + W K G  V     R  L   G   LR T+  +  D G Y C A 
Sbjct: 1251 AELECRTLGVPTPQVEWTKDGQPVFLGEPRVQLQEDGQV-LRITNSHL-GDEGWYQCVAF 1308

Query: 89   NSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLECLPPRGSPEPNVYWKKNGQ 147
            +  G  ++++  L +      +     S+ +  +G  V   C   RG P P++ W K+G 
Sbjct: 1309 SPAGQ-QTKDFQLRIHAPPTIWGSNETSEVAVMEGHPVWFLC-EARGVPTPDITWFKDGD 1366

Query: 148  TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI-- 205
             L+      ++   G  L ++ A+ +DAG Y C A NA G  E     L++++ P +   
Sbjct: 1367 PLV-PSTEVVYTRGGRQLQLERAQGSDAGTYSCKASNAVGVVEKT-TRLEVYVPPTIEGT 1424

Query: 206  -TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
              GP  V A  G  +T +C   G P P V W           G       G L L+++  
Sbjct: 1425 GEGPRVVKAVAGRPLTLECVARGYPPPTVSWYHEGLPVVDRNGTWLGAGGGVLSLESLGE 1484

Query: 265  ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES--GNVARFTCTATGRPEP 322
            A  G YSC A +  G       + V   P + ++     V +  G      C A+G P P
Sbjct: 1485 ASGGLYSCVASSPAGEAVLHYSVEVQVAPQLLVAEGLGQVTTLVGQSLYLPCYASGSPVP 1544

Query: 323  TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
            T+ W   G+     PG+     H T+  +G T L I+  +   +     C A N AG++ 
Sbjct: 1545 TIQWLQNGHPAEELPGV-----HVTS--EGTT-LHIDHVELGHA-GLFACQATNEAGTAA 1595

Query: 383  VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH 442
               +L+V       P ++  G  N T P        C     P P + W+ +G AL    
Sbjct: 1596 AEVELSV----HELPSVVIVGGENITAPFLQPVTLRCAGTGVPTPSLRWWKDGVAL---- 1647

Query: 443  RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
                 + G+L ++ +D  D GTYTCVA++  G+
Sbjct: 1648 ---AASGGSLQIEKVDLKDEGTYTCVATNLAGE 1677



 Score =  132 bits (320), Expect = 4e-29
 Identities = 120/466 (25%), Positives = 193/466 (41%), Gaps = 28/466 (6%)

Query: 78  SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDTVVLECLPPRGSP 136
           ++ G Y C A +  GT R++     + V     +L P    +   G+T +L CL    +P
Sbjct: 460 AEEGTYECTAVSRAGTGRAKT---QIVVTGPPPQLVPVPNVTVSPGETAILSCLVLSEAP 516

Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
             N+ W ++ + L         L D  +L +++   +D GRYQC+A N+ G   +++  L
Sbjct: 517 Y-NLTWVRDWRVLSASTGRVTQLADL-SLEVRNTTPSDGGRYQCMASNSNGVTRASVWLL 574

Query: 197 KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS 256
            +   P +           G  V  +C   G P P + W R  G       RV+V   G+
Sbjct: 575 -VREAPQVSIHTRSQRFSQGMEVRVRCSASGYPAPHISWSRE-GRALQEDSRVRVDAQGT 632

Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316
           L +  V   D G YSC+A N +G    +  L   DPPS++     V    G  A   C A
Sbjct: 633 LIIQGVAPEDAGSYSCQAANEIGRDEETVTLYYTDPPSVSAVNGVVLAAKGEEAVLECEA 692

Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
           TG P P + W       I+ P  S           G+  L I    + D+     C AVN
Sbjct: 693 TGVPPPRVIWYRGDLEMILAPEDS---------ISGM--LRIPVVRERDA-GVYTCRAVN 740

Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF-EG 435
             G +    +L V        P +   P + T+ +   A+  C A   P P I W+  + 
Sbjct: 741 ELGDASAEIRLEVGH-----APQLLELPQDVTVELGRSALLACRATGHPLPTITWHRGDD 795

Query: 436 EAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHF 494
           + L ++  R ++  DG+L L      D+G Y+CV S+  G +     L+V   + P I  
Sbjct: 796 QPLGLRGSRHSIRADGSLHLDQALLEDAGRYSCVVSNTAGSHHRDVQLVVQVKVPPRIQP 855

Query: 495 FRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQV 540
                +++   P + P   +   T  T++W++     +S    Y V
Sbjct: 856 TATHHITNEGVPASLPCVASGVPTP-TITWTKETNALASRDPHYNV 900



 Score =  132 bits (320), Expect = 4e-29
 Identities = 133/508 (26%), Positives = 197/508 (38%), Gaps = 53/508 (10%)

Query: 21   VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
            V  A+ + A L C A G P P + WY+G + ++     SI    G+  +     R   DA
Sbjct: 678  VLAAKGEEAVLECEATGVPPPRVIWYRGDLEMILAPEDSI---SGMLRIPVVRER---DA 731

Query: 81   GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
            GVY C A N  G A S    L V    +   L P+      G + +L C    G P P +
Sbjct: 732  GVYTCRAVNELGDA-SAEIRLEVGHAPQLLEL-PQDVTVELGRSALLACRAT-GHPLPTI 788

Query: 141  YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA-TLKIH 199
             W +     L    SR  +   G+L +  A   DAGRY C+  N AG+    +   +++ 
Sbjct: 789  TWHRGDDQPLGLRGSRHSIRADGSLHLDQALLEDAGRYSCVVSNTAGSHHRDVQLVVQVK 848

Query: 200  IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL 259
            + P +       +   G   +  C   G P P + W +             V  DG+L +
Sbjct: 849  VPPRIQPTATHHITNEGVPASLPCVASGVPTPTITWTKETNALASRDPHYNVSKDGTLVI 908

Query: 260  DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS------------------ 301
                + D G Y C A N+VG  S    L+V   P   L P                    
Sbjct: 909  PRPSVQDAGAYVCTATNAVGFSSQEMRLSVNMEPGFLLDPKHGATAKPRILVNGSHEADK 968

Query: 302  ---VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
               V  ++G+     C A G P P + W+ +    +       D++H          L +
Sbjct: 969  PLRVTAKAGDEVTLDCEAQGSPPPLVTWTKDSRHMLPIT----DRHHLLPPGS----LHL 1020

Query: 359  NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
                 +DS     C+A N AGS+     L V     + PP +  GP    + +       
Sbjct: 1021 AQAQVSDS-GLYECTASNPAGSATQYYILRV-----QVPPQVQPGPRVLKVLVGEAVDLN 1074

Query: 419  CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVW 478
            C A  +PEP + W  +G AL     R    +G++    +  S +GTY C ASS  G   W
Sbjct: 1075 CVAEGSPEPRVTWSKDGVAL-----RGEGPEGSVHFAAIQTSHAGTYRCEASSSAGVDAW 1129

Query: 479  SGALLVDSPINPNI-HFFRAADVSSLPG 505
               L V  P  P++    R A+VS + G
Sbjct: 1130 ELDLRVLVP--PSLREDGRRANVSGMAG 1155



 Score =  125 bits (302), Expect = 6e-27
 Identities = 84/265 (31%), Positives = 125/265 (47%), Gaps = 13/265 (4%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
            D+++     A L C A GSP P + W K G  V     +  +   G   ++ +  +   D
Sbjct: 3911 DLSITEGAHALLPCTATGSPEPKVTWEKDGQPVSGAKGKFTIQPSGELLVKNSESQ---D 3967

Query: 80   AGVYWCEATNSYGTARSRNATLHVAVLR-EEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
            AG Y C A N+ G AR R   +H+ +L    F   P  +    GD + L C   RGSP P
Sbjct: 3968 AGTYTCTAENAVGRARRR---VHLTILALPVFTTLPGDRSLRLGDKLWLHCAA-RGSPTP 4023

Query: 139  NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA-RQTDAGRYQCIARNAAGTRESAIATLK 197
             + W  N +  L      +   DGG+ + + A  + D+G Y C A N  G R  A++ + 
Sbjct: 4024 QIGWTVNNR--LVTATEGVSEQDGGSTLQRVAVTREDSGTYVCWAENRVG-RVQAVSFVH 4080

Query: 198  IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257
            +   P     P+DV  ++G SV  +C+  G+P P + W R AG       R++ L DGSL
Sbjct: 4081 VKGVPVFQVKPQDVTVRSGDSVALRCQASGEPAPTMEWLR-AGQPVRASQRLQTLPDGSL 4139

Query: 258  RLDNVILADEGEYSCEAENSVGAVS 282
             L+ V   D G Y C A N +G+ +
Sbjct: 4140 WLERVEARDAGPYECVAHNLLGSAT 4164



 Score =  124 bits (300), Expect = 1e-26
 Identities = 123/477 (25%), Positives = 191/477 (40%), Gaps = 37/477 (7%)

Query: 6    VTSGEAPYI--IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
            +T  + PYI   +QP ++ +    P  L C A G+P+P I W+K G  +           
Sbjct: 3349 LTVMDPPYIEDSDQPEELLLTPGTPLELLCDARGTPTPNITWHKDGRALSWPEDGQ---- 3404

Query: 64   GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
            G    LR    +V SDAG+Y C A +  G           A         P         
Sbjct: 3405 GARRVLRVEGVQV-SDAGLYTCLAHSPAGEVEKSFRIRVQAPPNVIGSHGPRFVVGLAPG 3463

Query: 124  TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
             +VLEC      P P + W + G  L  D  ++    +G  L +Q     D+G Y C A 
Sbjct: 3464 QLVLEC-SVEADPAPEIEWHREGVLLQADAHTQFP-EEGRFLQLQALSTADSGDYSCTAH 3521

Query: 184  NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA---- 239
            NAAG+      +L  H++   +  P  V A    +    C+  G P P V W +      
Sbjct: 3522 NAAGS-----TSLAFHVE---VHRPPTVNASVNQTTLLPCQADGVPQPLVSWLKDGVPLD 3573

Query: 240  -GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
             G     L R + L +G LR+  V+  D G Y C A N  G+      L V++PP+I   
Sbjct: 3574 PGSTRWVLAR-EGLREG-LRIQPVLAEDAGHYLCLASNPAGSDRQGRDLQVFEPPAIAPG 3631

Query: 299  PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
            P+++ + +   A   C A+G P+P + W  +G +      + +  Y           L +
Sbjct: 3632 PSNLTLTAYTPASLPCEASGSPKPLVAWWKDGQKLDF--RLQQGAYRLLP----SNALLL 3685

Query: 359  NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
             +    DS     C   N  G +     +TV       PP I +  ++ T  I +  V  
Sbjct: 3686 EEPSPQDSA-LFECVVSNGVGEARKLYWVTV-----HVPPAIADDQTDFTATIMAPVVLT 3739

Query: 419  CTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
            C +   P P+++W   G  L ++ +   V+  G L +       +G YTC A +  G
Sbjct: 3740 CHSTGVPAPVVSWSKAGTRLGVRGNGYRVSPSGALEIGQALPIHTGRYTCAARNAAG 3796



 Score =  122 bits (293), Expect = 8e-26
 Identities = 133/497 (26%), Positives = 201/497 (40%), Gaps = 47/497 (9%)

Query: 30   TLNCRAGGSPSPAIRWYKGGVLV----VSDTHR-SILPAGGLFFLRATHGRVHSDAGVYW 84
            TL C +   P P I WYK G  +    V+   R  IL  G L  ++ T     SD+G Y 
Sbjct: 2537 TLECESWAVPPPTISWYKDGQNLPEKPVTPNQRVRILGEGRLLQIQPTQV---SDSGRYL 2593

Query: 85   CEATNSYGTA-RSRNATLH---VAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSPEPN 139
            C ATN  G   +  N  +         EE R    E ++  + +   L C      P   
Sbjct: 2594 CVATNVAGEDDQDFNVLIQDFETPFWGEEARGGVTEYREIVENNPAYLYC-DTNAVPAAE 2652

Query: 140  VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
            + W +  + L  + D    L  G  L I   R  DAGRY C A N  G  E  +    + 
Sbjct: 2653 LTWYRGDRPLSIE-DGVSVLQGGRVLQIPLVRAEDAGRYSCKASNEVG--EDWLHYELLV 2709

Query: 200  IKPYLITGP-----EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254
            + P +I G      E+V     S+V+  C V G+P P + W ++ G    P  R++VL++
Sbjct: 2710 LTPPVILGETEELVEEVTVNANSTVSLHCPVLGNPAPTISWLQN-GLPFSPSPRLQVLEN 2768

Query: 255  GS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313
            G  L++    +AD   Y C AEN  G+      L V   P +N  P  +     +     
Sbjct: 2769 GRILQVSTAEVADAASYMCVAENPAGSTEKLFTLRVQGEPGLN--PEQITATLNSSVSLP 2826

Query: 314  CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
            C     P P + W  +G  T+    +  + +    +  G   L +      DS    +C 
Sbjct: 2827 CDVRAHPSPEVTWYKDG-WTL---SLGEEIF----LLPGTHTLQLTRVQLLDS-GMYICE 2877

Query: 374  AVNYAGSSFVRGKLTVTSDD--DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431
            A+N AG      +L+V +     RP  ++     ++       AV  C     PEP +AW
Sbjct: 2878 ALNAAGRDHKLVQLSVLAPGAPSRPQDVVLVSAGDK-------AVLSCETDAFPEPTVAW 2930

Query: 432  YFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
              +G+ L+   R      G  L ++D   SD G Y+C  S+  G+ + + +L V  P  P
Sbjct: 2931 QKDGQPLVLPERIQALLGGQRLEIQDAQVSDKGLYSCRVSNAAGEAMRAFSLTVQVP--P 2988

Query: 491  NIHFFRAADVSSLPGPP 507
                     VS + G P
Sbjct: 2989 TFENPETEMVSRVAGSP 3005



 Score =  120 bits (288), Expect = 3e-25
 Identities = 136/481 (28%), Positives = 210/481 (43%), Gaps = 55/481 (11%)

Query: 16   EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75
            E P  V     +P TL C A G P P + WY  G+ VV D + + L AGG      + G 
Sbjct: 1426 EGPRVVKAVAGRPLTLECVARGYPPPTVSWYHEGLPVV-DRNGTWLGAGGGVLSLESLGE 1484

Query: 76   VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDTVVLECLPPRG 134
              +  G+Y C A++  G A   + ++ V V  +    E   + +   G ++ L C    G
Sbjct: 1485 --ASGGLYSCVASSPAGEA-VLHYSVEVQVAPQLLVAEGLGQVTTLVGQSLYLPCYAS-G 1540

Query: 135  SPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
            SP P + W +NG     +    +H+  +G  L I       AG + C A N AGT  +A 
Sbjct: 1541 SPVPTIQWLQNGHPA--EELPGVHVTSEGTTLHIDHVELGHAGLFACQATNEAGT-AAAE 1597

Query: 194  ATLKIHIKP-YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL 252
              L +H  P  +I G E++ A     VT +C   G P P + W +         G     
Sbjct: 1598 VELSVHELPSVVIVGGENITAPFLQPVTLRCAGTGVPTPSLRWWKD--------GVALAA 1649

Query: 253  DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN---VESGNV 309
              GSL+++ V L DEG Y+C A N  G       L V  PP  N+ P  VN   +E+ +V
Sbjct: 1650 SGGSLQIEKVDLKDEGTYTCVATNLAGESRKEVILRVLVPP--NIEPGLVNKAVLENASV 1707

Query: 310  ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
                C A+G P P   W +         G+  D+    AV+ GV    +        +  
Sbjct: 1708 T-LECLASGVPPPGKVWEL---------GLGNDE---PAVW-GVLYSLL--------KIC 1745

Query: 370  IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI- 428
            +V   +   G    R  LTV +     P   +  PS  ++P ++ A+F C+   + +   
Sbjct: 1746 LVGGLLAGVGCEGARLALTVLA-----PGCSSLCPSLPSIPSQTTAIF-CSHPSSFQAFS 1799

Query: 429  -IAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
             I+W+   + +    R  V+ DG  L+++    SD+G+Y CVAS+  G      +L V++
Sbjct: 1800 NISWFKGRQPISAWDRAMVSTDGRVLLIEQAQLSDAGSYRCVASNVVGSTELQYSLRVNA 1859

Query: 487  P 487
            P
Sbjct: 1860 P 1860



 Score =  118 bits (285), Expect = 7e-25
 Identities = 125/488 (25%), Positives = 191/488 (39%), Gaps = 33/488 (6%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG---GLFFLRATHGRV 76
            +VT   H P +L C A G P P IRW++G    VS    + L AG     + L+ T  + 
Sbjct: 2238 NVTATLHSPLSLFCEATGIPPPGIRWFRGEE-PVSPGENTYLLAGKKISGWMLKLTRAQ- 2295

Query: 77   HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
              D G+Y C A+N  G AR       V VL    R                   P  G P
Sbjct: 2296 EQDRGLYSCLASNEAGEAR---RDFSVEVLGTSPRGSHGRPPILPSSLRASGSGPSTGHP 2352

Query: 137  EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
            +P V W K+GQ L   GD+     DG  L +  A  + AG Y C+A NA G +      L
Sbjct: 2353 QPKVTWFKDGQPLA-SGDAHHVSPDGALLWVLHANLSSAGHYACVAANAIGEKTKHF-QL 2410

Query: 197  KIHIKPYLITGPED-----VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
             + + P ++   ED     V     + ++  C     P P + W +  G     L  +++
Sbjct: 2411 SVLVVPTILGVTEDSMDEEVTVTINNPISLICETRAFPTPTITWMKD-GVPFEALNNIQL 2469

Query: 252  L-DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN-------LSPNSVN 303
            L     L++ N    D G+Y+C   N +G    + ++ V  PPSI+       +S   V 
Sbjct: 2470 LPGTHGLQILNAQKEDAGQYTCVVTNELGEAMKNYHVEVLIPPSISKDDLFGEVSMKEVK 2529

Query: 304  VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
             +  +     C +   P PT+ W  +G      P           +     +L I  T  
Sbjct: 2530 TKVNSTLTLECESWAVPPPTISWYKDGQN---LPEKPVTPNQRVRILGEGRLLQIQPTQV 2586

Query: 364  NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP--PPIITNGPSN-QTLPIKSMAVFPCT 420
            +DS    +C A N AG       + +  D + P        G +  + +   + A   C 
Sbjct: 2587 SDS-GRYLCVATNVAGEDDQDFNVLI-QDFETPFWGEEARGGVTEYREIVENNPAYLYCD 2644

Query: 421  AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS-DSGTYTCVASSRHGKYVWS 479
                P   + WY     L      +V   G ++   L ++ D+G Y+C AS+  G+    
Sbjct: 2645 TNAVPAAELTWYRGDRPLSIEDGVSVLQGGRVLQIPLVRAEDAGRYSCKASNEVGEDWLH 2704

Query: 480  GALLVDSP 487
              LLV +P
Sbjct: 2705 YELLVLTP 2712



 Score =  112 bits (269), Expect = 6e-23
 Identities = 98/367 (26%), Positives = 150/367 (40%), Gaps = 22/367 (5%)

Query: 116  SKQSAQGDTVVLECLPPRGSPE-PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTD 174
            S  S    T  + C  P       N+ W K G+  +   D  M   DG  L+I+ A+ +D
Sbjct: 1776 SLPSIPSQTTAIFCSHPSSFQAFSNISWFK-GRQPISAWDRAMVSTDGRVLLIEQAQLSD 1834

Query: 175  AGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL 234
            AG Y+C+A N  G+ E    +L+++  P ++   ++V      SV  +CR    P P + 
Sbjct: 1835 AGSYRCVASNVVGSTELQY-SLRVNAPPSILGEEQNVSVVANESVALECRSHAVPPPVLS 1893

Query: 235  WRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
            WR+         G     D   L +D   + D G Y+CEA N VG       L V+ PP 
Sbjct: 1894 WRKDGRPLEPRPGVYLSADKALLEVDRAEVGDTGRYTCEALNQVGRSEKHYNLNVWVPPV 1953

Query: 295  I-NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
              +  P ++ V  G+ AR +C   G P P + W  +G      PG    +  + A    V
Sbjct: 1954 FPSREPRTLTVTEGHPARLSCDCRGVPFPKISWKKDGQP---LPG----EGVSLAQVSAV 2006

Query: 354  TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413
              L      +     T  C   N AG+S    +L V      PP I   GP      +  
Sbjct: 2007 GRLLYLGRAQPAQEGTYTCECSNVAGNSSQDQQLVVYV----PPRIA--GPLEPYADVSV 2060

Query: 414  M----AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCV 468
            +    A   C A   P P + W  +G  +       + N G +L ++    + +G Y+CV
Sbjct: 2061 VQDEEASLECNATGKPAPRVTWERDGWPVGPESGLRLQNHGQSLHVERAQPAHAGRYSCV 2120

Query: 469  ASSRHGK 475
            A +  G+
Sbjct: 2121 AENEAGR 2127



 Score =   99 bits (238), Expect = 4e-19
 Identities = 86/309 (27%), Positives = 127/309 (41%), Gaps = 20/309 (6%)

Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVG 226
           I  A + + G Y+C A + AGT  +    +     P L+  P +V    G +    C V 
Sbjct: 454 IPRASKAEEGTYECTAVSRAGTGRAKTQIVVTGPPPQLVPVP-NVTVSPGETAILSCLVL 512

Query: 227 GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY 286
            +   ++ W R     +   GRV  L D SL + N   +D G Y C A NS G   AS +
Sbjct: 513 SEAPYNLTWVRDWRVLSASTGRVTQLADLSLEVRNTTPSDGGRYQCMASNSNGVTRASVW 572

Query: 287 LTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHA 346
           L V + P +++   S     G   R  C+A+G P P + WS EG R +      R     
Sbjct: 573 LLVREAPQVSIHTRSQRFSQGMEVRVRCSASGYPAPHISWSREG-RALQEDSRVRVDAQG 631

Query: 347 TAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN 406
           T +  GV           +   +  C A N  G    R + TVT     PP +  +  + 
Sbjct: 632 TLIIQGVA---------PEDAGSYSCQAANEIG----RDEETVTLYYTDPPSV--SAVNG 676

Query: 407 QTLPIK-SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465
             L  K   AV  C A   P P + WY     +I     +++  G L +  + + D+G Y
Sbjct: 677 VVLAAKGEEAVLECEATGVPPPRVIWYRGDLEMILAPEDSIS--GMLRIPVVRERDAGVY 734

Query: 466 TCVASSRHG 474
           TC A +  G
Sbjct: 735 TCRAVNELG 743



 Score = 97.5 bits (232), Expect = 2e-18
 Identities = 82/284 (28%), Positives = 119/284 (41%), Gaps = 14/284 (4%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P I+ +  +V+V  ++   L CR+   P P + W K G  +  +    +  +     L  
Sbjct: 1861 PSILGEEQNVSVVANESVALECRSHAVPPPVLSWRKDGRPL--EPRPGVYLSADKALLEV 1918

Query: 72   THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
                V  D G Y CEA N  G +  ++  L+V V       EP +    +G    L C  
Sbjct: 1919 DRAEV-GDTGRYTCEALNQVGRS-EKHYNLNVWVPPVFPSREPRTLTVTEGHPARLSC-D 1975

Query: 132  PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRE 190
             RG P P + WKK+GQ L  +G S   +   G L+ +  A+    G Y C   N AG   
Sbjct: 1976 CRGVPFPKISWKKDGQPLPGEGVSLAQVSAVGRLLYLGRAQPAQEGTYTCECSNVAG-NS 2034

Query: 191  SAIATLKIHIKPYLITGP----EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
            S    L +++ P  I GP     DV        + +C   G P P V W R  G    P 
Sbjct: 2035 SQDQQLVVYVPP-RIAGPLEPYADVSVVQDEEASLECNATGKPAPRVTWERD-GWPVGPE 2092

Query: 247  GRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
              +++ + G SL ++    A  G YSC AEN  G       L+V
Sbjct: 2093 SGLRLQNHGQSLHVERAQPAHAGRYSCVAENEAGRAERRFSLSV 2136



 Score = 93.1 bits (221), Expect = 4e-17
 Identities = 86/299 (28%), Positives = 123/299 (41%), Gaps = 24/299 (8%)

Query: 43   IRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTAR---SRNA 99
            I W+KG    +S   R+++   G   L        SDAG Y C A+N  G+     S   
Sbjct: 1801 ISWFKGRQ-PISAWDRAMVSTDGRVLL--IEQAQLSDAGSYRCVASNVVGSTELQYSLRV 1857

Query: 100  TLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL 159
                ++L EE     ++      ++V LEC      P P + W+K+G+ L  +    ++L
Sbjct: 1858 NAPPSILGEE-----QNVSVVANESVALEC-RSHAVPPPVLSWRKDGRPL--EPRPGVYL 1909

Query: 160  -VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGS 217
              D   L +  A   D GRY C A N  G  E     L + + P +    P  +    G 
Sbjct: 1910 SADKALLEVDRAEVGDTGRYTCEALNQVGRSEKHY-NLNVWVPPVFPSREPRTLTVTEGH 1968

Query: 218  SVTFQCRVGGDPLPDVLWRRSA---GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEA 274
                 C   G P P + W++      G  + L +V  +    L L     A EG Y+CE 
Sbjct: 1969 PARLSCDCRGVPFPKISWKKDGQPLPGEGVSLAQVSAV-GRLLYLGRAQPAQEGTYTCEC 2027

Query: 275  ENSVGAVSASGYLTVYDPPSI--NLSPNS-VNVESGNVARFTCTATGRPEPTMFWSVEG 330
             N  G  S    L VY PP I   L P + V+V     A   C ATG+P P + W  +G
Sbjct: 2028 SNVAGNSSQDQQLVVYVPPRIAGPLEPYADVSVVQDEEASLECNATGKPAPRVTWERDG 2086



 Score = 88.6 bits (210), Expect = 9e-16
 Identities = 118/476 (24%), Positives = 190/476 (39%), Gaps = 47/476 (9%)

Query: 17   QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD--THRSILPAGGLFFLRATHG 74
            +P  +TV    PA L+C   G P P I W K G  +  +  +   +   G L +L    G
Sbjct: 1958 EPRTLTVTEGHPARLSCDCRGVPFPKISWKKDGQPLPGEGVSLAQVSAVGRLLYL----G 2013

Query: 75   RVH-SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS-AQGDTVVLECLPP 132
            R   +  G Y CE +N  G +      +     R    LEP +  S  Q +   LEC   
Sbjct: 2014 RAQPAQEGTYTCECSNVAGNSSQDQQLVVYVPPRIAGPLEPYADVSVVQDEEASLEC-NA 2072

Query: 133  RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
             G P P V W+++G  +  +   R+    G +L ++ A+   AGRY C+A N AG  E  
Sbjct: 2073 TGKPAPRVTWERDGWPVGPESGLRLQ-NHGQSLHVERAQPAHAGRYSCVAENEAGRAERR 2131

Query: 193  IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV---GGDPLPDVLWRRSAG--GGNMPLG 247
             +   +   P    G ++   Q  S  ++   +   G  PL +     S      N    
Sbjct: 2132 FSLSVLGEDPQPSGGGQEAARQPLSPCSWGHLLVLPGARPLANAALSGSCEHCSQNQDRL 2191

Query: 248  RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSP-NSVNV 304
            ++ ++   S  L++  +   G    E        +   YL    PP +  +L P  +V  
Sbjct: 2192 QIALISLPSPHLNSYCIPQGGGEEWEE-------TRREYLV---PPELIGDLGPLTNVTA 2241

Query: 305  ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
               +     C ATG P P + W   G    + PG   + Y          +L +    + 
Sbjct: 2242 TLHSPLSLFCEATGIPPPGIRW-FRGEEP-VSPG--ENTYLLAGKKISGWMLKLTRAQEQ 2297

Query: 365  DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR----PPPIITNGPSNQTLPIKSMAVFPCT 420
            D R    C A N AG +     + V     R     PPI+   PS+    +++    P T
Sbjct: 2298 D-RGLYSCLASNEAGEARRDFSVEVLGTSPRGSHGRPPIL---PSS----LRASGSGPST 2349

Query: 421  AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHGK 475
                P+P + W+ +G+ L      +V+ DG L+ +   + S +G Y CVA++  G+
Sbjct: 2350 G--HPQPKVTWFKDGQPLASGDAHHVSPDGALLWVLHANLSSAGHYACVAANAIGE 2403



 Score = 62.1 bits (144), Expect = 9e-08
 Identities = 67/246 (27%), Positives = 94/246 (38%), Gaps = 21/246 (8%)

Query: 248  RVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
            R  V  DG  L ++   L+D G Y C A N VG+      L V  PPSI     +V+V +
Sbjct: 1815 RAMVSTDGRVLLIEQAQLSDAGSYRCVASNVVGSTELQYSLRVNAPPSILGEEQNVSVVA 1874

Query: 307  GNVARFTCTATGRPEPTMFWSVEGNRTIIFPG--MSRDKYHATAVFDGVTVLTINDTDKN 364
                   C +   P P + W  +G      PG  +S DK           +L ++  +  
Sbjct: 1875 NESVALECRSHAVPPPVLSWRKDGRPLEPRPGVYLSADK----------ALLEVDRAEVG 1924

Query: 365  DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
            D+     C A+N  G S     L V      PP   +  P   T+     A   C     
Sbjct: 1925 DT-GRYTCEALNQVGRSEKHYNLNVWV----PPVFPSREPRTLTVTEGHPARLSCDCRGV 1979

Query: 425  PEPIIAWYFEGEALIQN--HRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHGKYVWSGA 481
            P P I+W  +G+ L         V+  G L+ L     +  GTYTC  S+  G       
Sbjct: 1980 PFPKISWKKDGQPLPGEGVSLAQVSAVGRLLYLGRAQPAQEGTYTCECSNVAGNSSQDQQ 2039

Query: 482  LLVDSP 487
            L+V  P
Sbjct: 2040 LVVYVP 2045


>UniRef50_Q92859 Cluster: Neogenin precursor; n=34;
           Euteleostomi|Rep: Neogenin precursor - Homo sapiens
           (Human)
          Length = 1461

 Score =  168 bits (409), Expect = 7e-40
 Identities = 186/730 (25%), Positives = 288/730 (39%), Gaps = 84/730 (11%)

Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
           F +EP    S +G +V+L C      P P + WKK+G  L    D R  L+  G+L I +
Sbjct: 55  FLVEPVDTLSVRGSSVILNC-SAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISN 113

Query: 170 A-----RQTDAGRYQCIAR-NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223
                  + D G YQC+A   + GT  S  A L +   P   + PE      G++    C
Sbjct: 114 VVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYAGNNAILNC 173

Query: 224 RVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA 280
            V  D +P V W ++      PL    RV  L  G L + N    D G Y C  E+  G 
Sbjct: 174 EVNADLVPFVRWEQN----RQPLLLDDRVIKLPSGMLVISNATEGDGGLYRCVVESG-GP 228

Query: 281 VSASGYLTVY---DPPSIN-----LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332
              S  + +    DP  I+       P+ +    G      C A+G P PT+ W      
Sbjct: 229 PKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEE- 287

Query: 333 TIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD 392
                 +  +      +  G + L I+D  ++D+  T  C A N   +   + +LTV + 
Sbjct: 288 -----ALDTESSERLVLLAGGS-LEISDVTEDDA-GTYFCIADNGNETIEAQAELTVQAQ 340

Query: 393 DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTL 452
                P     P+N         VF C     P P + W   G+ +I +    +  +  L
Sbjct: 341 -----PEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNL 395

Query: 453 VLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPIT 512
            +  L KSD G Y C+A +  G    +GA L+     P       A    LP  P   + 
Sbjct: 396 QVLGLVKSDEGFYQCIAENDVGN-AQAGAQLIILEHAP-------ATTGPLPSAPRDVVA 447

Query: 513 HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHY 572
             V+   + L+W           L Y V  +++E ++       S           +   
Sbjct: 448 SLVSTRFIKLTWRTPASDPHGDNLTYSV-FYTKEGIARERVENTS--------HPGEMQV 498

Query: 573 VVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILT 632
            +++L+P   Y+F V  +N HG SG S  S  + V         G     +   R    +
Sbjct: 499 TIQNLMPATVYIFRVMAQNKHG-SGES--SAPLRVETQPEVQLPGP----APNLRAYAAS 551

Query: 633 DHIVELIEATPIDSKTIKLMWEILNF--YYLEGLFIYFRPLDNITIEYEMKTILHSNDVS 690
              + +   TP+         EI N+  YY+E      +  D    E ++    HS  ++
Sbjct: 552 PTSITVTWETPVSGN-----GEIQNYKLYYME------KGTDK---EQDVDVSSHSYTIN 597

Query: 691 GFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHL 750
           G     L+KYT+Y F ++ + K   G  +     +TL DVP   P N+ + + N+ ++ +
Sbjct: 598 G-----LKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMI 652

Query: 751 KWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQI 810
            W PP    QNG ITGY +        + KS V          S ++  L  G  Y+ ++
Sbjct: 653 HWQPPAPATQNGQITGYKIRYR---KASRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRV 709

Query: 811 AAETIIGLGP 820
           AA TI G GP
Sbjct: 710 AALTINGTGP 719



 Score =  162 bits (393), Expect = 6e-38
 Identities = 144/569 (25%), Positives = 232/569 (40%), Gaps = 45/569 (7%)

Query: 13  YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGLFFLR 70
           Y + +P+D    R     LNC A   PSP I W K G  +  VSD  R +LP G LF   
Sbjct: 54  YFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISN 113

Query: 71  ATHGRVHS-DAGVYWCEAT-NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
             H + +  D G Y C AT  S GT  SR A L VA L   F  +PE      G+  +L 
Sbjct: 114 VVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGL-PRFTSQPEPSSVYAGNNAILN 172

Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
           C        P V W++N Q LL D   R+  +  G LVI +A + D G Y+C+  +    
Sbjct: 173 C-EVNADLVPFVRWEQNRQPLLLD--DRVIKLPSGMLVISNATEGDGGLYRCVVESGGPP 229

Query: 189 RESAIATLKIHIKPYLITG------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
           + S    LK+   P +I+       P  +V   G  V   C   G P P + W ++    
Sbjct: 230 KYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEAL 289

Query: 243 NMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
           +     R+ +L  GSL + +V   D G Y C A+N    + A   LTV   P     P +
Sbjct: 290 DTESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTN 349

Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
           +         F C  TG+P PT+ W   G+  ++ P      Y        + VL +  +
Sbjct: 350 IYAHESMDIVFECEVTGKPTPTVKWVKNGD--MVIP----SDYFKIVKEHNLQVLGLVKS 403

Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT- 420
           D+   +    C A N  G++    +L +          + + P +    + S      T 
Sbjct: 404 DEGFYQ----CIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTW 459

Query: 421 AICTPEP-----IIAWYFEGEALIQNHRRNVTNDGTL--VLKDLDKSDSGTYTCVASSRH 473
                +P       + ++  E + +    N ++ G +   +++L  +    +  +A ++H
Sbjct: 460 RTPASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKH 519

Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSS 533
           G    S  L V++   P +          LPGP      +  + TS+T++W +    G+ 
Sbjct: 520 GSGESSAPLRVET--QPEV---------QLPGPAPNLRAYAASPTSITVTW-ETPVSGNG 567

Query: 534 SILGYQVEVFSRETLSGNNTPRNSRGWVV 562
            I  Y++    + T    +   +S  + +
Sbjct: 568 EIQNYKLYYMEKGTDKEQDVDVSSHSYTI 596



 Score =  135 bits (326), Expect = 8e-30
 Identities = 190/826 (23%), Positives = 326/826 (39%), Gaps = 74/826 (8%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P    QP   +V     A LNC       P +RW +    ++ D     LP+G L    A
Sbjct: 152 PRFTSQPEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPLLLDDRVIKLPSGMLVISNA 211

Query: 72  THGRVHSDAGVYWCEATNSYGTARSRNATLHV----AVLRE-EFRLEPESKQSAQGDTVV 126
           T G    D G+Y C   +      S    L V     V+ +  F  +P       G  VV
Sbjct: 212 TEG----DGGLYRCVVESGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVV 267

Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
           L C+   G P P + W KN + L  +   R+ L+ GG+L I D  + DAG Y CIA N  
Sbjct: 268 LPCV-ASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGN 326

Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
            T E A A L +  +P  +  P ++ A     + F+C V G P P V W ++ G   +P 
Sbjct: 327 ETIE-AQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKN-GDMVIPS 384

Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PPSINLSPNSV-N 303
              K++ + +L++  ++ +DEG Y C AEN VG   A   L + +  P +    P++  +
Sbjct: 385 DYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRD 444

Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIF--PGMSRDKYHATAVFDGVTVLTINDT 361
           V +  V+      T R   +         ++ +   G++R++   T+   G   +TI   
Sbjct: 445 VVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARERVENTS-HPGEMQVTI--- 500

Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
            +N    T+    V  A +    G+ +     +  P +   GP+     +++ A  P + 
Sbjct: 501 -QNLMPATVYIFRV-MAQNKHGSGESSAPLRVETQPEVQLPGPAPN---LRAYAASPTSI 555

Query: 422 ICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
             T E  ++    G   IQN++      GT   +D+D S S +YT     ++ +Y  S  
Sbjct: 556 TVTWETPVS----GNGEIQNYKLYYMEKGTDKEQDVDVS-SHSYTINGLKKYTEY--SFR 608

Query: 482 LLVDSPINPNIHFFRAA--DVSSLPGPPTKPITHNVTDT-SVTLSWS-QNNKIGSSSILG 537
           ++  +   P +     A   +S +P    + ++  V ++ S+ + W        +  I G
Sbjct: 609 VVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITG 668

Query: 538 YQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSG 597
           Y++  + + +   + T     G         Q   +++ L  G  Y F V       ++G
Sbjct: 669 YKIR-YRKASRKSDVTETLVSG--------TQLSQLIEGLDRGTEYNFRVAALT---ING 716

Query: 598 PSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILN 657
             P +D ++     + L E       +      L   IV  +  TP +++ I +      
Sbjct: 717 TGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIV--VSWTPPENQNIVVRG---- 770

Query: 658 FYYLEGLFIYFRPLDNITIEYEMKTILHSN-DVSGFEITSLRKYTKYEFFLIPFYKKFEG 716
             Y  G  I       I ++Y+ +     N D S   + +L+ +       IP Y+    
Sbjct: 771 --YAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEG-IPLYESAVT 827

Query: 717 KPS-----------NSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIIT 765
           +P            N+      D  P  PP+ ++  IL+  T+ + W+   L     I  
Sbjct: 828 RPHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITD 887

Query: 766 GYNVVVNW-LDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQI 810
                V W  ++PAN      N T     S ++T L     Y   +
Sbjct: 888 SRYYTVRWKTNIPANTKYKNANAT---TLSYLVTGLKPNTLYEFSV 930



 Score = 79.0 bits (186), Expect = 7e-13
 Identities = 81/301 (26%), Positives = 127/301 (42%), Gaps = 20/301 (6%)

Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
           A  +    +S  A+++     Y +  P D ++  GSSV   C    +P P + W++    
Sbjct: 33  AARSGSAPQSPGASIRTFTPFYFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTF 92

Query: 242 GNMPL-GRVKVLDDGSLRLDNVILA-----DEGEYSCEAE-NSVGA-VSASGYLTVYDPP 293
            N+    R ++L DGSL + NV+ +     DEG Y C A   S+G  +S +  L V   P
Sbjct: 93  LNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLP 152

Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
                P   +V +GN A   C       P + W  E NR    P +  D+     +  G+
Sbjct: 153 RFTSQPEPSSVYAGNNAILNCEVNADLVPFVRW--EQNRQ---PLLLDDR--VIKLPSGM 205

Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIK 412
            V++ N T+ +      V  +      S    +L V  D +    ++    PS     I 
Sbjct: 206 LVIS-NATEGDGGLYRCVVESGGPPKYS-DEVELKVLPDPEVISDLVFLKQPSPLVRVIG 263

Query: 413 SMAVFPCTAICTPEPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470
              V PC A   P P I W    EAL    + R  +   G+L + D+ + D+GTY C+A 
Sbjct: 264 QDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIAD 323

Query: 471 S 471
           +
Sbjct: 324 N 324



 Score = 46.0 bits (104), Expect = 0.006
 Identities = 38/136 (27%), Positives = 57/136 (41%), Gaps = 5/136 (3%)

Query: 694  ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILN--TTTVHLK 751
            +T L+  T YEF ++    +     S +    T + VP  PP ++ +        T+ + 
Sbjct: 917  VTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVPTSPPKDVTVVSKEGKPKTIIVN 976

Query: 752  WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811
            W PP     NG ITGY ++    DV A      I   V    +  +  LT    Y  +I 
Sbjct: 977  WQPPSEA--NGKITGY-IIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQ 1033

Query: 812  AETIIGLGPFSQKVYF 827
            A    G+GP S+ V F
Sbjct: 1034 ARNSKGMGPMSEAVQF 1049


>UniRef50_O94779 Cluster: Contactin-5 precursor; n=52;
           Euteleostomi|Rep: Contactin-5 precursor - Homo sapiens
           (Human)
          Length = 1100

 Score =  167 bits (405), Expect = 2e-39
 Identities = 136/491 (27%), Positives = 206/491 (41%), Gaps = 33/491 (6%)

Query: 12  PYIIEQPLDV---TVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
           P  +++P D+   T +  +   LNC   G+P P+ RW + G  +  ++        G F 
Sbjct: 99  PVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFI 158

Query: 69  LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
           +  ++     D+G Y C ATN+ G+  SR ATL  A L         +    +G  VVL 
Sbjct: 159 I--SNPSEAKDSGHYQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLM 216

Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAG 187
           C PP  SPE    W  N        DSR  +  + GNL I   + +D G Y C+ +N   
Sbjct: 217 CSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTVT 276

Query: 188 TRESAIATLKIHIKPYLITG----------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
                     + ++   + G          P  V A  G++V  +C   G+P+P + W +
Sbjct: 277 NARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMK 336

Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
               G +P           L + NV L D G Y C AENS G  S  G L VY  P    
Sbjct: 337 V--NGYIPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVE 394

Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
             N   ++SG+  R+ C ATG+P PT  W   G   +     SR       + +G  VL 
Sbjct: 395 KLNDTQLDSGSPLRWECKATGKPRPTYRWLKNG---VPLSPQSR-----VEMVNG--VLM 444

Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM-AV 416
           I++ +++D+     C A N  G+ +   +L + +     P    N      +  K    V
Sbjct: 445 IHNVNQSDA-GMYQCLAENKYGAIYASAELKILAS---APTFALNQLKKTIIVTKDQEVV 500

Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476
             C    +P+P I+W     A+ +N R  +  DG+L + +  KSD G Y C   +  G  
Sbjct: 501 IECKPQGSPKPTISWKKGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSA 560

Query: 477 VWSGALLVDSP 487
               +L V  P
Sbjct: 561 EIIASLSVKEP 571



 Score =  119 bits (287), Expect = 4e-25
 Identities = 98/336 (29%), Positives = 143/336 (42%), Gaps = 19/336 (5%)

Query: 1   MSDDYVTSGEAPYI-IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRS 59
           + +D V     P I +  P  VT A+     + C A G+P P I W K    + S     
Sbjct: 289 LRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLR 348

Query: 60  ILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS 119
              A     L   + ++  DAG+Y C A NS G   S    L V         +    Q 
Sbjct: 349 KSQA----VLEIPNVQL-DDAGIYECRAENSRGK-NSFRGQLQVYTYPHWVE-KLNDTQL 401

Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179
             G  +  EC    G P P   W KNG  L     SR+ +V+G  L+I +  Q+DAG YQ
Sbjct: 402 DSGSPLRWEC-KATGKPRPTYRWLKNGVPL--SPQSRVEMVNGV-LMIHNVNQSDAGMYQ 457

Query: 180 CIARNAAGTRESAIATLKIHIK-PYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
           C+A N  G   ++ A LKI    P        + ++      V  +C+  G P P + W+
Sbjct: 458 CLAENKYGAIYAS-AELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWK 516

Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
           +          R+ +L DGSLR+ N   +DEG+Y C  EN  G+      L+V +P  I 
Sbjct: 517 KGDRAVRENK-RIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIE 575

Query: 297 LSPNSVNVESGNVARFTCTA--TGRPEPTMFWSVEG 330
           L+P    +  G      C A      + T +W+++G
Sbjct: 576 LTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKG 611



 Score =  107 bits (258), Expect = 1e-21
 Identities = 91/320 (28%), Positives = 135/320 (42%), Gaps = 27/320 (8%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P+ +E+  D  +    P    C+A G P P  RW K GV  +S   R  +  G L     
Sbjct: 390 PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGV-PLSPQSRVEMVNGVLMI--- 445

Query: 72  THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS--AQGDTVVLEC 129
            H    SDAG+Y C A N YG   + +A L +      F L    K     +   VV+EC
Sbjct: 446 -HNVNQSDAGMYQCLAENKYGAIYA-SAELKILASAPTFALNQLKKTIIVTKDQEVVIEC 503

Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
             P+GSP+P + WKK  + +    + R+ ++  G+L I +A ++D G+Y C   N  G+ 
Sbjct: 504 -KPQGSPKPTISWKKGDRAVR--ENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSA 560

Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL--WRRSAG------- 240
           E  IA+L +     +   P+      G S+   C+   D   DV   W            
Sbjct: 561 E-IIASLSVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEE 619

Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
           GG+    R +      L + N++L   G Y C  + +  +VS    L V  PP     P 
Sbjct: 620 GGHFESIRAQA-SSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPG---PPG 675

Query: 301 SVNVESGNVARFTCTATGRP 320
            V VE   +   T T +  P
Sbjct: 676 IVIVE--EITESTATLSWSP 693


>UniRef50_UPI0000F2B6E2 Cluster: PREDICTED: hypothetical protein; n=1;
            Monodelphis domestica|Rep: PREDICTED: hypothetical
            protein - Monodelphis domestica
          Length = 3881

 Score =  166 bits (404), Expect = 3e-39
 Identities = 143/475 (30%), Positives = 198/475 (41%), Gaps = 34/475 (7%)

Query: 11   APYIIEQ--PLDVTVARHQPATLNCRAGGSPSPAIRWYKGG--VLVVSDTHRSILPAGGL 66
            AP I+    P +  +   Q   L C A G P P I W K G  + V +  H      G  
Sbjct: 2854 APRILSSGVPQEHNILEEQEVRLECEAEGQPQPDISWLKDGRPLGVHTAPHLRFYTDGSS 2913

Query: 67   FFLRATHGRVHSDAGVYWCEATNSYGT-ARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
              L+   G   SD+G Y C A NS G   +    ++ V    E      E+  S QG+ V
Sbjct: 2914 LVLK---GLKSSDSGAYTCLAQNSVGEDTKLHTVSVLVPPTIERGANGSENLISVQGELV 2970

Query: 126  VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
             + C P RGSP   + W K+G  +     + +H   G  L I   +  DAG + C+A + 
Sbjct: 2971 TMAC-PARGSPPIQINWLKDGLPMPLSQRTHLHS-SGRTLRISQVQVADAGTFTCVASSP 3028

Query: 186  AGTRESAIATLKIHIKPYLITGP-EDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
            AG  E   + L+IH+ P L     +D +A   GS VT  C   G PLP V W +   G +
Sbjct: 3029 AGVAERTFS-LQIHVPPVLEPSETKDAMAVVRGSDVTLPCEARGSPLPAVSWLKD--GAS 3085

Query: 244  MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS--PNS 301
            + L R+ +    SL+L+ V   D G YSC A N  G  +    L V +PP I  S     
Sbjct: 3086 LMLQRLGLGSGSSLQLEAVQADDVGTYSCVAINEAGEATRHFQLAVMEPPHIEDSGQAEE 3145

Query: 302  VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
            + +  G      C A G P P + W  +G        +++D        +GV V      
Sbjct: 3146 MLLLPGAPLELICNALGSPMPNITWQKDGQVLARLGSITKD--GRVLRVEGVQV------ 3197

Query: 362  DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI-KSMAVFPCT 420
               D      C A N AG       + V +    PP I+ +  +   + +     V  C 
Sbjct: 3198 ---DDAGLYTCLAENPAGEDGKNFLVRVQA----PPNIVGSRETRTVIGLADGQLVLECP 3250

Query: 421  AICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
                P P I W+ EG  L    H   + N   L L+ LD SDSG Y CVAS+  G
Sbjct: 3251 VEADPPPKIEWHREGVLLQADAHTLFLENGRFLQLQALDTSDSGDYNCVASNAAG 3305



 Score =  165 bits (400), Expect = 9e-39
 Identities = 136/481 (28%), Positives = 213/481 (44%), Gaps = 34/481 (7%)

Query: 16   EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGLFFLRATH 73
            ++P+ +T    +  TL+C A GSPSP I W K   L+  ++D H S+LP+G L     + 
Sbjct: 987  DRPVTITALAGKELTLHCEAEGSPSPLITWTKDSQLLSPITDRH-SLLPSGSLKLAETSV 1045

Query: 74   GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
                 D G+Y C A+N  GTA SR+  L V V   + +  P+  +   G+++ L C+   
Sbjct: 1046 ----EDNGLYTCIASNPAGTA-SRSYVLGVQV-PPQIQQGPQLLKVLAGESLDLTCVAT- 1098

Query: 134  GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
            G P+P + W K+G TL   G     +   G++ ++  + +D+G Y C+A + AG     +
Sbjct: 1099 GDPKPQLRWSKDGITLPQKG----WVGPDGSVHLESVQVSDSGHYHCVASSEAGEDAREL 1154

Query: 194  ATLKIHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR-VKV 251
                +    +     E ++ +  G + +  C V G P P V+WR+      +     + V
Sbjct: 1155 ELEVLEPPRWEAEDAEALLERVAGENASLPCPVTGTPTPRVIWRKDPAPELLSSQPGLSV 1214

Query: 252  LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE--SGNV 309
            L+D SL + +V   D G+Y C A N VG+VS    L VY PP        VNV   +   
Sbjct: 1215 LNDSSLFIASVSSQDSGDYECRATNEVGSVSRKVKLVVYVPPHFRGEEQRVNVSTLASRP 1274

Query: 310  ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
                C  +G P P + W  +G        +S D  H     DG   L      K+DS + 
Sbjct: 1275 LTLNCDVSGFPTPAITWYKDGR------PVSEDNRHYFP--DGAPSLHFPQVQKSDS-DL 1325

Query: 370  IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPI 428
              C AVN AG +     L V      PP +   G + +   +  + V   C     P P 
Sbjct: 1326 YTCQAVNPAGMAQKDFNLLVLI----PPSVRGAGTAQEVSRLAGLEVELECRTSGVPLPQ 1381

Query: 429  IAWYFEGEALIQN--HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
            + W  +G+ +     H + V +   L +      D+G Y CVA S  G+      L + +
Sbjct: 1382 VEWTKDGQPVAPGDPHIQLVEDGQVLKIPSSHLGDAGHYQCVAFSPAGQQAKDFQLSIQT 1441

Query: 487  P 487
            P
Sbjct: 1442 P 1442



 Score =  164 bits (399), Expect = 1e-38
 Identities = 135/461 (29%), Positives = 197/461 (42%), Gaps = 31/461 (6%)

Query: 21   VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
            + V R    TL C A GSP PA+ W K G  ++    R  L +G    L A       D 
Sbjct: 3055 MAVVRGSDVTLPCEARGSPLPAVSWLKDGASLM--LQRLGLGSGSSLQLEAVQA---DDV 3109

Query: 81   GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
            G Y C A N  G A        +     E   + E      G  + L C    GSP PN+
Sbjct: 3110 GTYSCVAINEAGEATRHFQLAVMEPPHIEDSGQAEEMLLLPGAPLELIC-NALGSPMPNI 3168

Query: 141  YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
             W+K+GQ L   G       DG  L ++  +  DAG Y C+A N AG  +     +++  
Sbjct: 3169 TWQKDGQVLARLGSITK---DGRVLRVEGVQVDDAGLYTCLAENPAG-EDGKNFLVRVQA 3224

Query: 201  KPYLITGPED--VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-L 257
             P ++   E   V+      +  +C V  DP P + W R  G           L++G  L
Sbjct: 3225 PPNIVGSRETRTVIGLADGQLVLECPVEADPPPKIEWHRE-GVLLQADAHTLFLENGRFL 3283

Query: 258  RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
            +L  +  +D G+Y+C A N+ G+ S    + ++  P+I   P+ VNV     A   C   
Sbjct: 3284 QLQALDTSDSGDYNCVASNAAGSTSLPFSVEIHMAPTIQPGPSVVNVSVNETALLPCKTR 3343

Query: 318  GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
            G P   + W  +G   +  PG  R ++    + DG   L I      DS    +C A N 
Sbjct: 3344 GLPVSLVSWRKDGIPLV--PGSPRLEF----LSDGS--LRIQPVYPQDS-GYYLCQASNS 3394

Query: 378  AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437
            AGS     +L V       PP I  GPSN TL + + A  PC A  +P+P + W   G+ 
Sbjct: 3395 AGSDRQGRELRVFE-----PPTIAPGPSNLTLTVHTQATLPCEARGSPKPHVVWKKNGQT 3449

Query: 438  L-IQNHRR--NVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
            L +  H+    +    +LVL D D  D+  + C+ S+  G+
Sbjct: 3450 LSLDRHQEAYRLLPSSSLVLTDPDLQDTAQFECLVSNDAGE 3490



 Score =  162 bits (394), Expect = 5e-38
 Identities = 140/470 (29%), Positives = 211/470 (44%), Gaps = 30/470 (6%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
           + P  +  P +VTV+  + A L+C+        + W +   ++ +   R +  A      
Sbjct: 427 DPPPQLASPQNVTVSPGETALLSCQVLDKAPYNLTWVRDWRVLPASPGRVVQLAN---LS 483

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVVL 127
               G + SD G Y C A+N+ G  R+    L    +RE  +  +   S+  +QG  + +
Sbjct: 484 LEISGIIPSDGGKYQCLASNANGITRASVWLL----IREPPQISINTSSRHFSQGVELRI 539

Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
            C    G P P++ W+ N QT+  DG  R  + D G L+IQ     DAG Y C A N  G
Sbjct: 540 SCTAS-GYPPPHISWRHNDQTIGMDG--RFLVDDQGTLIIQSVTPEDAGNYSCQATNEVG 596

Query: 188 TRESAIATLKIHIKPYLITGPEDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
           T E  + TL  + +P  ++    VV A  G     +C+  G P P V+W R  GG  M L
Sbjct: 597 TDEQTV-TL-FYTEPPSVSALRPVVLAPIGEEAVLECKASGVPPPRVIWYR--GGLEMIL 652

Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV-YDPPSINLSPNSVNVE 305
              +V   G+LR+  V   D G Y C+A N +GA SA   L V Y P  +  S N V VE
Sbjct: 653 AP-EVAHTGTLRIQEVQERDAGNYICKAVNELGAASADIRLEVGYAPRLVESSRNMV-VE 710

Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
            G  A   C A GRP P + W+    + +  P    +   A  +  GV  L  N T ++ 
Sbjct: 711 MGRNAILACRAEGRPSPRITWARVDGKPV--PAHPVEGNRARQLEAGVLFLE-NVTPEDQ 767

Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC-T 424
           +    +C A N  G +    +LTV   +   PP I +  S   +     A  PC  +   
Sbjct: 768 A--LYICEAHNTFGKAQAEVQLTVIGHE---PPQIASSASMVRVLEGQPASLPCVVLAGK 822

Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
           P P   W  EG+ L  + R ++  DG+  +    + D+G Y+CV ++  G
Sbjct: 823 PFPQRHWLKEGQPL-PSSRYSIRTDGSFHIDRALQEDAGRYSCVVTNTVG 871



 Score =  161 bits (391), Expect = 1e-37
 Identities = 150/501 (29%), Positives = 214/501 (42%), Gaps = 46/501 (9%)

Query: 16   EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG--LFFLRATH 73
            EQ ++V+    +P TLNC   G P+PAI WYK G   VS+ +R   P G   L F +   
Sbjct: 1262 EQRVNVSTLASRPLTLNCDVSGFPTPAITWYKDG-RPVSEDNRHYFPDGAPSLHFPQVQK 1320

Query: 74   GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
                SD+ +Y C+A N  G A+     L +           +      G  V LEC    
Sbjct: 1321 ----SDSDLYTCQAVNPAGMAQKDFNLLVLIPPSVRGAGTAQEVSRLAGLEVELECRTS- 1375

Query: 134  GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESA 192
            G P P V W K+GQ +   GD  + LV+ G ++ I  +   DAG YQC+A + AG +++ 
Sbjct: 1376 GVPLPQVEWTKDGQPVA-PGDPHIQLVEDGQVLKIPSSHLGDAGHYQCVAFSPAG-QQAK 1433

Query: 193  IATLKIHIKPYLITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250
               L I   P +    E  +V       V  QC   G P P + W +  G       RV 
Sbjct: 1434 DFQLSIQTPPTIWGSNETGEVAVMEDHVVRLQCDARGVPTPAITWLKD-GDPLHASPRVA 1492

Query: 251  VLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI---NLSPNSVNVES 306
                G  L+L     +D G Y+C+A N+ G    +  L VY PP+I   +  P  V   +
Sbjct: 1493 YAKGGRHLQLGRARGSDSGLYTCQASNAAGIAEKAVRLDVYVPPTIEGADGGPLVVKAVA 1552

Query: 307  GNVARFTCTATGRPEPTMFWS------VEGNRTIIFPGMSRDKY----HATAVFDGVTVL 356
            G      C+A+G P PT+ W        E N T +  G    ++         F GV V 
Sbjct: 1553 GRPLALGCSASGHPPPTLTWHQDENPLTENNGTWLQEGGRVLRWLRNGRPAEEFAGVEVS 1612

Query: 357  TIN-----DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
            T       D  + D      C A N AG++    ++ V    ++P   +  G  N T P 
Sbjct: 1613 TDGAMLRIDHVQPDHNGLFACQATNEAGTAGAEVEVLV---HEQPSVTVLEG-ENITAPF 1668

Query: 412  KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
                   C A   P P ++W+  G +L       VT  G+L ++ +D  D G YTCVA++
Sbjct: 1669 LQPVTIQCVAAGMPVPNLSWWKNGVSL-------VTTGGSLQIEKVDLRDEGNYTCVATN 1721

Query: 472  RHGKYVWSGALLVDSPINPNI 492
              G+      L V  P  PNI
Sbjct: 1722 LAGEAKRDVVLKVLVP--PNI 1740



 Score =  158 bits (383), Expect = 1e-36
 Identities = 133/479 (27%), Positives = 195/479 (40%), Gaps = 36/479 (7%)

Query: 9    GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLV----VSDTHRSILPA 63
            G AP ++E   ++ V   + A L CRA G PSP I W +  G  V    V       L A
Sbjct: 695  GYAPRLVESSRNMVVEMGRNAILACRAEGRPSPRITWARVDGKPVPAHPVEGNRARQLEA 754

Query: 64   GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
            G LF    T      D  +Y CEA N++G A++      +     +        +  +G 
Sbjct: 755  GVLFLENVT----PEDQALYICEAHNTFGKAQAEVQLTVIGHEPPQIASSASMVRVLEGQ 810

Query: 124  TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
               L C+   G P P  +W K GQ L     SR  +   G+  I  A Q DAGRY C+  
Sbjct: 811  PASLPCVVLAGKPFPQRHWLKEGQPL---PSSRYSIRTDGSFHIDRALQEDAGRYSCVVT 867

Query: 184  NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
            N  G++   I  L + + P ++      V   G  ++  C   G P P + WR+     +
Sbjct: 868  NTVGSQRQDI-ELAVQVLPSILPTASHYVTNEGVPISLPCVSRGIPTPTITWRKETNALS 926

Query: 244  MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS----- 298
                  +VL +GSL L      D G Y C A N++G  S    L+V   P I ++     
Sbjct: 927  PRSSHHQVLKEGSLYLPQPSAQDSGTYVCTATNALGISSQEIQLSVNTKPRIIMNESLDS 986

Query: 299  --PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
              P ++   +G      C A G P P + W+ +    ++ P   R     + +  G   L
Sbjct: 987  DRPVTITALAGKELTLHCEAEGSPSPLITWTKDSQ--LLSPITDRH----SLLPSGSLKL 1040

Query: 357  TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416
                 + N     I  +    A  S+V G         + PP I  GP    +       
Sbjct: 1041 AETSVEDNGLYTCIASNPAGTASRSYVLGV--------QVPPQIQQGPQLLKVLAGESLD 1092

Query: 417  FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
              C A   P+P + W  +G  L Q  +  V  DG++ L+ +  SDSG Y CVASS  G+
Sbjct: 1093 LTCVATGDPKPQLRWSKDGITLPQ--KGWVGPDGSVHLESVQVSDSGHYHCVASSEAGE 1149



 Score =  155 bits (376), Expect = 7e-36
 Identities = 130/500 (26%), Positives = 221/500 (44%), Gaps = 38/500 (7%)

Query: 5    YVTSGEAPYIIEQPLDVTVAR--HQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
            +V   + P I E P   T+++    P  L C   G P+P + W K  + V S   R ++ 
Sbjct: 2755 FVLIVQVPPIFENPEKETLSQVAGNPLVLVCDVAGVPAPTVTWLKDRMPVESSVERGVVS 2814

Query: 63   AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122
             GG   L        S  G Y C A N    AR     + +   R      P+     + 
Sbjct: 2815 RGGRLQLSRLQ---PSQEGTYTCVAENPEAEARKDFVVMVLVAPRILSSGVPQEHNILEE 2871

Query: 123  DTVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
              V LEC    G P+P++ W K+G+ L +          DG +LV++  + +D+G Y C+
Sbjct: 2872 QEVRLEC-EAEGQPQPDISWLKDGRPLGVHTAPHLRFYTDGSSLVLKGLKSSDSGAYTCL 2930

Query: 182  ARNAAGTRESAIATLKIHIKPYL---ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238
            A+N+ G  ++ + T+ + + P +     G E++++  G  VT  C   G P   + W + 
Sbjct: 2931 AQNSVG-EDTKLHTVSVLVPPTIERGANGSENLISVQGELVTMACPARGSPPIQINWLKD 2989

Query: 239  AGGGNMPLG-RVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
              G  MPL  R  +   G +LR+  V +AD G ++C A +  G    +  L ++ PP + 
Sbjct: 2990 --GLPMPLSQRTHLHSSGRTLRISQVQVADAGTFTCVASSPAGVAERTFSLQIHVPPVLE 3047

Query: 297  LS--PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
             S   +++ V  G+     C A G P P + W  +G   ++             +  G +
Sbjct: 3048 PSETKDAMAVVRGSDVTLPCEARGSPLPAVSWLKDGASLML---------QRLGLGSGSS 3098

Query: 355  VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
            +    +  + D   T  C A+N AG +    +L V      PP I  +G + + L +   
Sbjct: 3099 LQL--EAVQADDVGTYSCVAINEAGEATRHFQLAVM----EPPHIEDSGQAEEMLLLPGA 3152

Query: 415  AV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSR 472
             +   C A+ +P P I W  +G+ L +    ++T DG  L ++ +   D+G YTC+A + 
Sbjct: 3153 PLELICNALGSPMPNITWQKDGQVLAR--LGSITKDGRVLRVEGVQVDDAGLYTCLAENP 3210

Query: 473  HGKYVWSGALLVDSPINPNI 492
             G+   +  + V +P  PNI
Sbjct: 3211 AGEDGKNFLVRVQAP--PNI 3228



 Score =  153 bits (371), Expect = 3e-35
 Identities = 134/469 (28%), Positives = 202/469 (43%), Gaps = 25/469 (5%)

Query: 10   EAPYIIE--QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
            E P+I +  Q  ++ +    P  L C A GSP P I W K G ++      SI   G + 
Sbjct: 3133 EPPHIEDSGQAEEMLLLPGAPLELICNALGSPMPNITWQKDGQVLAR--LGSITKDGRV- 3189

Query: 68   FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV-AVLREEFRLEPESKQSAQGDTVV 126
             LR    +V  DAG+Y C A N  G    +N  + V A        E  +        +V
Sbjct: 3190 -LRVEGVQV-DDAGLYTCLAENPAGED-GKNFLVRVQAPPNIVGSRETRTVIGLADGQLV 3246

Query: 127  LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
            LEC P    P P + W + G  L  D  + + L +G  L +Q    +D+G Y C+A NAA
Sbjct: 3247 LEC-PVEADPPPKIEWHREGVLLQADAHT-LFLENGRFLQLQALDTSDSGDYNCVASNAA 3304

Query: 187  GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
            G+  S   +++IH+ P +  GP  V      +    C+  G P+  V WR+         
Sbjct: 3305 GST-SLPFSVEIHMAPTIQPGPSVVNVSVNETALLPCKTRGLPVSLVSWRKDGIPLVPGS 3363

Query: 247  GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
             R++ L DGSLR+  V   D G Y C+A NS G+      L V++PP+I   P+++ +  
Sbjct: 3364 PRLEFLSDGSLRIQPVYPQDSGYYLCQASNSAGSDRQGRELRVFEPPTIAPGPSNLTLTV 3423

Query: 307  GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
               A   C A G P+P + W   G        +S D++         + L + D D  D+
Sbjct: 3424 HTQATLPCEARGSPKPHVVWKKNGQT------LSLDRHQEAYRLLPSSSLVLTDPDLQDT 3477

Query: 367  RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
                 C   N AG +  R    VT      PP I +  ++ T+   +  V  C     P 
Sbjct: 3478 AQ-FECLVSNDAGET--RRLFWVTV---YVPPTIADDRTDFTVTKMAPVVLTCHTTGVPT 3531

Query: 427  PIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
            P+++W   G  L  +     V+  G L ++      +G YTC A +  G
Sbjct: 3532 PVVSWSKGGAQLGKRGSGYRVSPTGALEIEQALPIHTGRYTCTARNAAG 3580



 Score =  151 bits (365), Expect = 1e-34
 Identities = 131/482 (27%), Positives = 202/482 (41%), Gaps = 49/482 (10%)

Query: 18   PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR-- 75
            PL V     +P  L C A G P P + W++     +++ + + L  GG       +GR  
Sbjct: 1545 PLVVKAVAGRPLALGCSASGHPPPTLTWHQDEN-PLTENNGTWLQEGGRVLRWLRNGRPA 1603

Query: 76   -------VHSDA-------------GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPE 115
                   V +D              G++ C+ATN  GTA +    L V        LE E
Sbjct: 1604 EEFAGVEVSTDGAMLRIDHVQPDHNGLFACQATNEAGTAGAEVEVL-VHEQPSVTVLEGE 1662

Query: 116  SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175
            +  +     V ++C+   G P PN+ W KNG +L+           GG+L I+     D 
Sbjct: 1663 NITAPFLQPVTIQCVAA-GMPVPNLSWWKNGVSLV---------TTGGSLQIEKVDLRDE 1712

Query: 176  GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
            G Y C+A N AG  +  +  LK+ + P +  G  +      +S + +C   G P P + W
Sbjct: 1713 GNYTCVATNLAGEAKRDVV-LKVLVPPNIEPGLVNKAVLENTSASLECLASGVPTPRISW 1771

Query: 236  RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295
             R     +   G +   D   LR+    L+D G Y C A N  G+      L +  PP I
Sbjct: 1772 YRGRQPISSKPGLMVSSDGRVLRIKRAQLSDAGSYRCVASNVAGSSELKFGLRINVPPRI 1831

Query: 296  NLSPNSVN-VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
             L+P+    V      R  C ATG P P + W  +GN  +   G S        +F G  
Sbjct: 1832 TLAPSLPGPVLLNEPVRLVCNATGAPTPMLMWLKDGN-PVSATGTS-----GLQIFPGGH 1885

Query: 355  VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
            VLT+  +   D+  T  C AVN  G      +  VT     PP I+     N ++ +   
Sbjct: 1886 VLTLAGSRATDA-GTYTCVAVNAVGED----RRDVTLQVHLPPSIL-GEEQNVSVVVNQS 1939

Query: 415  AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRH 473
                C +   P P+++W  +G AL      +++ DG L+ ++  +  D G YTC A ++ 
Sbjct: 1940 VTLECQSQAVPPPVLSWRKDGHALSPRPGVHLSADGVLLQVERAEVQDVGRYTCEALNKA 1999

Query: 474  GK 475
            G+
Sbjct: 2000 GR 2001



 Score =  150 bits (363), Expect = 3e-34
 Identities = 134/507 (26%), Positives = 215/507 (42%), Gaps = 22/507 (4%)

Query: 4    DYVTSGEAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
            D V     P  IE  L +  V  +  A+L C A G P+P I WY+G   + S     +  
Sbjct: 1729 DVVLKVLVPPNIEPGLVNKAVLENTSASLECLASGVPTPRISWYRGRQPISSKPGLMVSS 1788

Query: 63   AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122
             G +  LR    ++ SDAG Y C A+N  G++  +   L + V      L P        
Sbjct: 1789 DGRV--LRIKRAQL-SDAGSYRCVASNVAGSSELKFG-LRINV-PPRITLAPSLPGPVLL 1843

Query: 123  DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCI 181
            +  V       G+P P + W K+G  +   G S + +  GG+ L +  +R TDAG Y C+
Sbjct: 1844 NEPVRLVCNATGAPTPMLMWLKDGNPVSATGTSGLQIFPGGHVLTLAGSRATDAGTYTCV 1903

Query: 182  ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
            A NA G     + TL++H+ P ++   ++V      SVT +C+    P P + WR+  G 
Sbjct: 1904 AVNAVGEDRRDV-TLQVHLPPSILGEEQNVSVVVNQSVTLECQSQAVPPPVLSWRKD-GH 1961

Query: 242  GNMPLGRVKVLDDGSL-RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL-SP 299
               P   V +  DG L +++   + D G Y+CEA N  G       L V+ PP  +   P
Sbjct: 1962 ALSPRPGVHLSADGVLLQVERAEVQDVGRYTCEALNKAGRSEKHYNLNVWVPPEFSFWEP 2021

Query: 300  NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
             ++ V  G+    +C   G P P + W  +G   +   G S +   A        +L + 
Sbjct: 2022 RTLAVTEGHPVSLSCECWGIPFPKITWKKDG-MLVPTDGGSTEPISAVG-----RLLYLG 2075

Query: 360  DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419
                +   N   C   N AG+S     L V      P    ++     ++         C
Sbjct: 2076 KAQPSQEGN-YTCECSNIAGNSSQEQHLEVYVAPKVPGS--SDFHKEVSVIHSGEVTLEC 2132

Query: 420  TAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKYVW 478
             A   P P++ W  +G+ + ++    + + G  L ++    + +G YTC+A +  G+   
Sbjct: 2133 EATGKPPPVVTWEKDGQLVTRDQGLLLQHRGRALQVEQARAAHAGRYTCIAENEAGRAEQ 2192

Query: 479  SGALLVDSPINPNIHFFRAADVSSLPG 505
               L V    +P I +FR  +  S PG
Sbjct: 2193 RFDLSVLGNPSPLIRWFRGEEPIS-PG 2218



 Score =  146 bits (353), Expect = 4e-33
 Identities = 140/492 (28%), Positives = 195/492 (39%), Gaps = 35/492 (7%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRA-GGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
            V   E P I      V V   QPA+L C    G P P   W K G  + S  + SI   G
Sbjct: 789  VIGHEPPQIASSASMVRVLEGQPASLPCVVLAGKPFPQRHWLKEGQPLPSSRY-SIRTDG 847

Query: 65   GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
                 RA    +  DAG Y C  TN+ G+ R ++  L V VL            + +G  
Sbjct: 848  SFHIDRA----LQEDAGRYSCVVTNTVGSQR-QDIELAVQVLPSILPTASHYVTN-EGVP 901

Query: 125  VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
            + L C+  RG P P + W+K    L     S   ++  G+L +      D+G Y C A N
Sbjct: 902  ISLPCVS-RGIPTPTITWRKETNALS-PRSSHHQVLKEGSLYLPQPSAQDSGTYVCTATN 959

Query: 185  AAGTRESAIATLKIHIKPYLITG-------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
            A G     I  L ++ KP +I         P  + A  G  +T  C   G P P + W +
Sbjct: 960  ALGISSQEIQ-LSVNTKPRIIMNESLDSDRPVTITALAGKELTLHCEAEGSPSPLITWTK 1018

Query: 238  SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
             +   +    R  +L  GSL+L    + D G Y+C A N  G  S S  L V  PP I  
Sbjct: 1019 DSQLLSPITDRHSLLPSGSLKLAETSVEDNGLYTCIASNPAGTASRSYVLGVQVPPQIQQ 1078

Query: 298  SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
             P  + V +G     TC ATG P+P + WS +G   I  P         +   + V V  
Sbjct: 1079 GPQLLKVLAGESLDLTCVATGDPKPQLRWSKDG---ITLPQKGWVGPDGSVHLESVQV-- 1133

Query: 358  INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
                  +DS +   C A + AG      +L V    + P     +  +         A  
Sbjct: 1134 ------SDSGH-YHCVASSEAGEDARELELEVL---EPPRWEAEDAEALLERVAGENASL 1183

Query: 418  PCTAICTPEPIIAWYFE--GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
            PC    TP P + W  +   E L      +V ND +L +  +   DSG Y C A++  G 
Sbjct: 1184 PCPVTGTPTPRVIWRKDPAPELLSSQPGLSVLNDSSLFIASVSSQDSGDYECRATNEVGS 1243

Query: 476  YVWSGALLVDSP 487
                  L+V  P
Sbjct: 1244 VSRKVKLVVYVP 1255



 Score =  141 bits (341), Expect = 1e-31
 Identities = 137/522 (26%), Positives = 221/522 (42%), Gaps = 35/522 (6%)

Query: 20   DVTVAR-HQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS 78
            D TV R    A L+C +   P P I WYK G  +  D     L  G    L   + +V +
Sbjct: 2679 DTTVVRVGDTAVLHCESDTLPEPVITWYKNGQQIALDQQVQTLLDGQK--LEIVNVQV-A 2735

Query: 79   DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
            D G+Y C+ +N  G A  R   L V V       E E+     G+ +VL C    G P P
Sbjct: 2736 DKGLYSCKVSNIVGEA-IRTFVLIVQVPPIFENPEKETLSQVAGNPLVLVC-DVAGVPAP 2793

Query: 139  NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
             V W K+ +  +     R  +  GG L +   + +  G Y C+A N           + +
Sbjct: 2794 TVTWLKD-RMPVESSVERGVVSRGGRLQLSRLQPSQEGTYTCVAENPEAEARKDFVVMVL 2852

Query: 199  HIKPYLITG-PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDG- 255
                 L +G P++        V  +C   G P PD+ W +     G      ++   DG 
Sbjct: 2853 VAPRILSSGVPQEHNILEEQEVRLECEAEGQPQPDISWLKDGRPLGVHTAPHLRFYTDGS 2912

Query: 256  SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI----NLSPNSVNVESGNVAR 311
            SL L  +  +D G Y+C A+NSVG  +    ++V  PP+I    N S N ++V+ G +  
Sbjct: 2913 SLVLKGLKSSDSGAYTCLAQNSVGEDTKLHTVSVLVPPTIERGANGSENLISVQ-GELVT 2971

Query: 312  FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371
              C A G P   + W  +G   +  P   R   H++        L I+     D+  T  
Sbjct: 2972 MACPARGSPPIQINWLKDG---LPMPLSQRTHLHSSG-----RTLRISQVQVADA-GTFT 3022

Query: 372  CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEPII 429
            C A + AG +     L +       PP++    +   + +   S    PC A  +P P +
Sbjct: 3023 CVASSPAGVAERTFSLQI-----HVPPVLEPSETKDAMAVVRGSDVTLPCEARGSPLPAV 3077

Query: 430  AWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPIN 489
            +W  +G +L+   R  + +  +L L+ +   D GTY+CVA +  G+      L V  P  
Sbjct: 3078 SWLKDGASLML-QRLGLGSGSSLQLEAVQADDVGTYSCVAINEAGEATRHFQLAVMEP-- 3134

Query: 490  PNIH-FFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530
            P+I    +A ++  LPG P + I + +      ++W ++ ++
Sbjct: 3135 PHIEDSGQAEEMLLLPGAPLELICNALGSPMPNITWQKDGQV 3176



 Score =  138 bits (333), Expect = 1e-30
 Identities = 129/475 (27%), Positives = 193/475 (40%), Gaps = 40/475 (8%)

Query: 27   QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
            + A L C+A G P P + WY+GG+ ++       +   G   ++    R   DAG Y C+
Sbjct: 625  EEAVLECKASGVPPPRVIWYRGGLEMILAPE---VAHTGTLRIQEVQER---DAGNYICK 678

Query: 87   ATNSYGTARSRNATLHVAVLREEFRLEPESKQSA--QGDTVVLECLPPRGSPEPNVYWKK 144
            A N  G A S +  L V       RL   S+      G   +L C    G P P + W +
Sbjct: 679  AVNELGAA-SADIRLEVGYAP---RLVESSRNMVVEMGRNAILACRA-EGRPSPRITWAR 733

Query: 145  -NGQTLLFDG--DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI-HI 200
             +G+ +       +R   ++ G L +++    D   Y C A N  G  ++ +    I H 
Sbjct: 734  VDGKPVPAHPVEGNRARQLEAGVLFLENVTPEDQALYICEAHNTFGKAQAEVQLTVIGHE 793

Query: 201  KPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL 259
             P + +    V    G   +  C V  G P P   W +   G  +P  R  +  DGS  +
Sbjct: 794  PPQIASSASMVRVLEGQPASLPCVVLAGKPFPQRHWLKE--GQPLPSSRYSIRTDGSFHI 851

Query: 260  DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGR 319
            D  +  D G YSC   N+VG+      L V   PSI  + +      G      C + G 
Sbjct: 852  DRALQEDAGRYSCVVTNTVGSQRQDIELAVQVLPSILPTASHYVTNEGVPISLPCVSRGI 911

Query: 320  PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379
            P PT+ W  E N       +S    H   + +G   L +      DS  T VC+A N  G
Sbjct: 912  PTPTITWRKETN------ALSPRSSHHQVLKEG--SLYLPQPSAQDS-GTYVCTATNALG 962

Query: 380  SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV------FPCTAICTPEPIIAWYF 433
             S    +L+V +     P II N   +   P+   A+        C A  +P P+I W  
Sbjct: 963  ISSQEIQLSVNT----KPRIIMNESLDSDRPVTITALAGKELTLHCEAEGSPSPLITWTK 1018

Query: 434  EGEALIQ-NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
            + + L     R ++   G+L L +    D+G YTC+AS+  G    S  L V  P
Sbjct: 1019 DSQLLSPITDRHSLLPSGSLKLAETSVEDNGLYTCIASNPAGTASRSYVLGVQVP 1073



 Score =  129 bits (311), Expect = 5e-28
 Identities = 136/504 (26%), Positives = 208/504 (41%), Gaps = 41/504 (8%)

Query: 2    SDDYVTSGEAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI 60
            S  YV   + P  I+Q P  + V   +   L C A G P P +RW K G+ +     +  
Sbjct: 1063 SRSYVLGVQVPPQIQQGPQLLKVLAGESLDLTCVATGDPKPQLRWSKDGITL---PQKGW 1119

Query: 61   LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS- 119
            +   G   L +      SD+G Y C A++  G   +R   L V    E  R E E  ++ 
Sbjct: 1120 VGPDGSVHLESVQV---SDSGHYHCVASSEAGED-ARELELEVL---EPPRWEAEDAEAL 1172

Query: 120  ---AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAG 176
                 G+   L C P  G+P P V W+K+    L      + +++  +L I      D+G
Sbjct: 1173 LERVAGENASLPC-PVTGTPTPRVIWRKDPAPELLSSQPGLSVLNDSSLFIASVSSQDSG 1231

Query: 177  RYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSS--VTFQCRVGGDPLPDVL 234
             Y+C A N  G+    +  L +++ P+     + V   T +S  +T  C V G P P + 
Sbjct: 1232 DYECRATNEVGSVSRKVK-LVVYVPPHFRGEEQRVNVSTLASRPLTLNCDVSGFPTPAIT 1290

Query: 235  WRRSAGGGNMPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
            W +   G  +         DG  SL    V  +D   Y+C+A N  G       L V  P
Sbjct: 1291 WYKD--GRPVSEDNRHYFPDGAPSLHFPQVQKSDSDLYTCQAVNPAGMAQKDFNLLVLIP 1348

Query: 293  PSINLSPNSVNVE--SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
            PS+  +  +  V   +G      C  +G P P + W+ +G    + PG      H   V 
Sbjct: 1349 PSVRGAGTAQEVSRLAGLEVELECRTSGVPLPQVEWTKDGQP--VAPGDP----HIQLVE 1402

Query: 351  DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
            DG  VL I  +   D+ +   C A + AG      +L++ +    PP I  +  + +   
Sbjct: 1403 DG-QVLKIPSSHLGDAGH-YQCVAFSPAGQQAKDFQLSIQT----PPTIWGSNETGEVAV 1456

Query: 411  IKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCV 468
            ++   V   C A   P P I W  +G+ L  + R      G  L L     SDSG YTC 
Sbjct: 1457 MEDHVVRLQCDARGVPTPAITWLKDGDPLHASPRVAYAKGGRHLQLGRARGSDSGLYTCQ 1516

Query: 469  ASSRHGKYVWSGALLVDSPINPNI 492
            AS+  G  +   A+ +D  + P I
Sbjct: 1517 ASNAAG--IAEKAVRLDVYVPPTI 1538



 Score =  129 bits (311), Expect = 5e-28
 Identities = 143/543 (26%), Positives = 217/543 (39%), Gaps = 65/543 (11%)

Query: 31   LNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
            L CR  G P P + W K G  V   D H  ++  G +  + ++H     DAG Y C A +
Sbjct: 1370 LECRTSGVPLPQVEWTKDGQPVAPGDPHIQLVEDGQVLKIPSSH---LGDAGHYQCVAFS 1426

Query: 90   SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV-LECLPPRGSPEPNVYWKKNGQT 148
              G  ++++  L +      +      + +   D VV L+C   RG P P + W K+G  
Sbjct: 1427 PAGQ-QAKDFQLSIQTPPTIWGSNETGEVAVMEDHVVRLQC-DARGVPTPAITWLKDGDP 1484

Query: 149  LLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT- 206
            L      R+    GG +L +  AR +D+G Y C A NAAG  E A+  L +++ P +   
Sbjct: 1485 L--HASPRVAYAKGGRHLQLGRARGSDSGLYTCQASNAAGIAEKAVR-LDVYVPPTIEGA 1541

Query: 207  --GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG------------GGN----MPLGR 248
              GP  V A  G  +   C   G P P + W +               GG     +  GR
Sbjct: 1542 DGGPLVVKAVAGRPLALGCSASGHPPPTLTWHQDENPLTENNGTWLQEGGRVLRWLRNGR 1601

Query: 249  -------VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN-LSP 299
                   V+V  DG+ LR+D+V     G ++C+A N  G   A   + V++ PS+  L  
Sbjct: 1602 PAEEFAGVEVSTDGAMLRIDHVQPDHNGLFACQATNEAGTAGAEVEVLVHEQPSVTVLEG 1661

Query: 300  NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
             ++           C A G P P + W   G   +   G                 L I 
Sbjct: 1662 ENITAPFLQPVTIQCVAAGMPVPNLSWWKNGVSLVTTGGS----------------LQIE 1705

Query: 360  DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419
              D  D  N   C A N AG +     L V       PP I  G  N+ +   + A   C
Sbjct: 1706 KVDLRDEGN-YTCVATNLAGEAKRDVVLKVLV-----PPNIEPGLVNKAVLENTSASLEC 1759

Query: 420  TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHGKYVW 478
             A   P P I+WY   + +       V++DG ++ +K    SD+G+Y CVAS+  G    
Sbjct: 1760 LASGVPTPRISWYRGRQPISSKPGLMVSSDGRVLRIKRAQLSDAGSYRCVASNVAGSSEL 1819

Query: 479  SGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSW-SQNNKIGSSSILG 537
               L ++ P  P I    +     L   P + + +     +  L W    N + ++   G
Sbjct: 1820 KFGLRINVP--PRITLAPSLPGPVLLNEPVRLVCNATGAPTPMLMWLKDGNPVSATGTSG 1877

Query: 538  YQV 540
             Q+
Sbjct: 1878 LQI 1880



 Score =  124 bits (298), Expect = 2e-26
 Identities = 117/409 (28%), Positives = 166/409 (40%), Gaps = 30/409 (7%)

Query: 78   SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ----GDTVVLECLPPR 133
            SD G Y CEA N  G  R +   L         +  P  ++       GDT VL C    
Sbjct: 2640 SDTGTYTCEALNVAG--RDQKLVLLSVFAPPTIKQTPGGQRDTTVVRVGDTAVLHCESDT 2697

Query: 134  GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
              PEP + W KNGQ +  D   +  L+DG  L I + +  D G Y C   N  G    AI
Sbjct: 2698 -LPEPVITWYKNGQQIALDQQVQT-LLDGQKLEIVNVQVADKGLYSCKVSNIVG---EAI 2752

Query: 194  ATLKIHIK-PYLITGPE-DVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250
             T  + ++ P +   PE + ++Q  G+ +   C V G P P V W +        + R  
Sbjct: 2753 RTFVLIVQVPPIFENPEKETLSQVAGNPLVLVCDVAGVPAPTVTWLKDRMPVESSVERGV 2812

Query: 251  VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS--PNSVNVESGN 308
            V   G L+L  +  + EG Y+C AEN          + V   P I  S  P   N+    
Sbjct: 2813 VSRGGRLQLSRLQPSQEGTYTCVAENPEAEARKDFVVMVLVAPRILSSGVPQEHNILEEQ 2872

Query: 309  VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
              R  C A G+P+P + W  +G      P       H     DG + L +     +DS  
Sbjct: 2873 EVRLECEAEGQPQPDISWLKDGR-----PLGVHTAPHLRFYTDG-SSLVLKGLKSSDS-G 2925

Query: 369  TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII--TNGPSNQTLPIKSMAVFPCTAICTPE 426
               C A N  G       ++V      PP I    NG  N       +    C A  +P 
Sbjct: 2926 AYTCLAQNSVGEDTKLHTVSVLV----PPTIERGANGSENLISVQGELVTMACPARGSPP 2981

Query: 427  PIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
              I W  +G  +  + R ++ + G TL +  +  +D+GT+TCVASS  G
Sbjct: 2982 IQINWLKDGLPMPLSQRTHLHSSGRTLRISQVQVADAGTFTCVASSPAG 3030



 Score =  123 bits (297), Expect = 3e-26
 Identities = 100/318 (31%), Positives = 147/318 (46%), Gaps = 22/318 (6%)

Query: 15   IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74
            IEQ L +   R+      C A  +   A   +K  +L+V  T   IL +G L   RA+  
Sbjct: 3560 IEQALPIHTGRY-----TCTARNAAGVA---HKHVILMVQGTGAQILSSGQLRISRASA- 3610

Query: 75   RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRG 134
                DAG Y C A N  GTA  +  T  V  +    +       +A+G   +L C+  +G
Sbjct: 3611 ---EDAGNYLCIAKNPSGTALGK--TRLVVQVPPVIKGGHSDLSAAEGSQALLPCI-AQG 3664

Query: 135  SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194
             PEP++ WKK+G  ++   + +  +   G L+++++ + DAG Y CIA NAAG   S   
Sbjct: 3665 IPEPHITWKKDG-FVVPSMEGKYTIQPSGELLVKNSERRDAGTYTCIAENAAG-HTSRRV 3722

Query: 195  TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254
             L I   P   T P D+    G  +  +C   G P P + W  +     +    V   D 
Sbjct: 3723 HLSILSLPTFTTLPGDLSLNHGDRLWLRCTARGSPTPHISWMVN---NRLVKEGVLEQDG 3779

Query: 255  GS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE-SGNVARF 312
            GS L+   V   D G Y+C AEN VG V A  ++ V + P++    +S  VE  G+ AR 
Sbjct: 3780 GSTLQRAAVTREDSGTYTCWAENIVGKVQAVSFVHVKEAPALQGEASSHLVELLGDSARL 3839

Query: 313  TCTATGRPEPTMFWSVEG 330
             C A G P P + W  +G
Sbjct: 3840 DCAARGDPAPVIRWIKDG 3857



 Score =  122 bits (293), Expect = 8e-26
 Identities = 128/463 (27%), Positives = 186/463 (40%), Gaps = 39/463 (8%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
            ++T    QP T+ C A G P P + W+K GV        S++  GG   +     R   D
Sbjct: 1663 NITAPFLQPVTIQCVAAGMPVPNLSWWKNGV--------SLVTTGGSLQIEKVDLR---D 1711

Query: 80   AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP--ESKQSAQGDTVVLECLPPRGSPE 137
             G Y C ATN  G A+ R+  L V V      +EP   +K   +  +  LECL   G P 
Sbjct: 1712 EGNYTCVATNLAGEAK-RDVVLKVLV---PPNIEPGLVNKAVLENTSASLECL-ASGVPT 1766

Query: 138  PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
            P + W + G+  +      M   DG  L I+ A+ +DAG Y+C+A N AG+ E     L+
Sbjct: 1767 PRISWYR-GRQPISSKPGLMVSSDGRVLRIKRAQLSDAGSYRCVASNVAGSSELKFG-LR 1824

Query: 198  IHIKPYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP-LGRVKVLDDG 255
            I++ P +   P           V   C   G P P ++W +     +      +++   G
Sbjct: 1825 INVPPRITLAPSLPGPVLLNEPVRLVCNATGAPTPMLMWLKDGNPVSATGTSGLQIFPGG 1884

Query: 256  S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
              L L      D G Y+C A N+VG       L V+ PPSI     +V+V         C
Sbjct: 1885 HVLTLAGSRATDAGTYTCVAVNAVGEDRRDVTLQVHLPPSILGEEQNVSVVVNQSVTLEC 1944

Query: 315  TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
             +   P P + W  +G+     PG+     H +A  DGV +L +   +  D      C A
Sbjct: 1945 QSQAVPPPVLSWRKDGHALSPRPGV-----HLSA--DGV-LLQVERAEVQDV-GRYTCEA 1995

Query: 375  VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFE 434
            +N AG S     L V      PP      P    +         C     P P I W  +
Sbjct: 1996 LNKAGRSEKHYNLNVWV----PPEFSFWEPRTLAVTEGHPVSLSCECWGIPFPKITWKKD 2051

Query: 435  GEALIQN--HRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHG 474
            G  +  +      ++  G L+ L     S  G YTC  S+  G
Sbjct: 2052 GMLVPTDGGSTEPISAVGRLLYLGKAQPSQEGNYTCECSNIAG 2094



 Score =  115 bits (276), Expect = 9e-24
 Identities = 116/428 (27%), Positives = 181/428 (42%), Gaps = 39/428 (9%)

Query: 29   ATLNCRAGGSPSPAIRWYKGGV--LVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
            A+L C   G+P+P + W K     L+ S    S+L    LF    +      D+G Y C 
Sbjct: 1181 ASLPCPVTGTPTPRVIWRKDPAPELLSSQPGLSVLNDSSLFIASVSS----QDSGDYECR 1236

Query: 87   ATNSYGTARSRNATLHVAVLREEFRLEPE--SKQSAQGDTVVLECLPPRGSPEPNVYWKK 144
            ATN  G+  SR   L V  +   FR E +  +  +     + L C    G P P + W K
Sbjct: 1237 ATNEVGSV-SRKVKL-VVYVPPHFRGEEQRVNVSTLASRPLTLNC-DVSGFPTPAITWYK 1293

Query: 145  NGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY 203
            +G+ +    D+R +  DG  +L     +++D+  Y C A N AG  +     L + I P 
Sbjct: 1294 DGRPV--SEDNRHYFPDGAPSLHFPQVQKSDSDLYTCQAVNPAGMAQKDF-NLLVLIPPS 1350

Query: 204  LITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLD 260
            +      ++V    G  V  +CR  G PLP V W +           +++++DG  L++ 
Sbjct: 1351 VRGAGTAQEVSRLAGLEVELECRTSGVPLPQVEWTKDGQPVAPGDPHIQLVEDGQVLKIP 1410

Query: 261  NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNVESGNVARFTCTATG 318
            +  L D G Y C A +  G  +    L++  PP+I  +     V V   +V R  C A G
Sbjct: 1411 SSHLGDAGHYQCVAFSPAGQQAKDFQLSIQTPPTIWGSNETGEVAVMEDHVVRLQCDARG 1470

Query: 319  RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
             P P + W  +G+     P ++  K        G   L +     +DS     C A N A
Sbjct: 1471 VPTPAITWLKDGDPLHASPRVAYAK--------GGRHLQLGRARGSDS-GLYTCQASNAA 1521

Query: 379  GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP----CTAICTPEPIIAWYFE 434
            G +    +  V  D   PP I   G     L +K++A  P    C+A   P P + W+ +
Sbjct: 1522 GIA----EKAVRLDVYVPPTI--EGADGGPLVVKAVAGRPLALGCSASGHPPPTLTWHQD 1575

Query: 435  GEALIQNH 442
               L +N+
Sbjct: 1576 ENPLTENN 1583



 Score =  112 bits (269), Expect = 6e-23
 Identities = 96/367 (26%), Positives = 152/367 (41%), Gaps = 26/367 (7%)

Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT 173
           P++   + G+T +L C     +P  N+ W ++ + L       + L +  +L I     +
Sbjct: 435 PQNVTVSPGETALLSCQVLDKAPY-NLTWVRDWRVLPASPGRVVQLANL-SLEISGIIPS 492

Query: 174 DAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233
           D G+YQC+A NA G   +++  L I   P +           G  +   C   G P P +
Sbjct: 493 DGGKYQCLASNANGITRASVWLL-IREPPQISINTSSRHFSQGVELRISCTASGYPPPHI 551

Query: 234 LWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
            WR +     M  GR  V D G+L + +V   D G YSC+A N VG    +  L   +PP
Sbjct: 552 SWRHNDQTIGMD-GRFLVDDQGTLIIQSVTPEDAGNYSCQATNEVGTDEQTVTLFYTEPP 610

Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
           S++     V    G  A   C A+G P P + W   G   I+ P ++             
Sbjct: 611 SVSALRPVVLAPIGEEAVLECKASGVPPPRVIWYRGGLEMILAPEVAH-----------T 659

Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413
             L I +  + D+ N I C AVN  G++    +L V        P +     N  + +  
Sbjct: 660 GTLRIQEVQERDAGNYI-CKAVNELGAASADIRLEVGY-----APRLVESSRNMVVEMGR 713

Query: 414 MAVFPCTAICTPEPIIAWY-FEGEAL----IQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468
            A+  C A   P P I W   +G+ +    ++ +R      G L L+++   D   Y C 
Sbjct: 714 NAILACRAEGRPSPRITWARVDGKPVPAHPVEGNRARQLEAGVLFLENVTPEDQALYICE 773

Query: 469 ASSRHGK 475
           A +  GK
Sbjct: 774 AHNTFGK 780



 Score =  106 bits (254), Expect = 4e-21
 Identities = 77/296 (26%), Positives = 121/296 (40%), Gaps = 16/296 (5%)

Query: 159  LVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSS 218
            ++  G L I  A   DAG Y CIA+N +GT       L + + P +  G  D+ A  GS 
Sbjct: 3597 ILSSGQLRISRASAEDAGNYLCIAKNPSGTALGK-TRLVVQVPPVIKGGHSDLSAAEGSQ 3655

Query: 219  VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSV 278
                C   G P P + W++         G+  +   G L + N    D G Y+C AEN+ 
Sbjct: 3656 ALLPCIAQGIPEPHITWKKDGFVVPSMEGKYTIQPSGELLVKNSERRDAGTYTCIAENAA 3715

Query: 279  GAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPG 338
            G  S   +L++   P+    P  +++  G+     CTA G P P + W V  N  ++  G
Sbjct: 3716 GHTSRRVHLSILSLPTFTTLPGDLSLNHGDRLWLRCTARGSPTPHISWMV--NNRLVKEG 3773

Query: 339  MSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398
            +           DG + L      + DS  T  C A N  G       + V       P 
Sbjct: 3774 VLEQ--------DGGSTLQRAAVTREDS-GTYTCWAENIVGKVQAVSFVHV----KEAPA 3820

Query: 399  IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVL 454
            +     S+    +   A   C A   P P+I W  +G  ++ +H ++   +G+L +
Sbjct: 3821 LQGEASSHLVELLGDSARLDCAARGDPAPVIRWIKDGLPVLSSHHKHQLQNGSLAI 3876



 Score =  105 bits (253), Expect = 6e-21
 Identities = 77/295 (26%), Positives = 124/295 (42%), Gaps = 8/295 (2%)

Query: 11   APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
            AP I   P  V V+ ++ A L C+  G P   + W K G+ +V  + R    + G   ++
Sbjct: 3318 APTIQPGPSVVNVSVNETALLPCKTRGLPVSLVSWRKDGIPLVPGSPRLEFLSDGSLRIQ 3377

Query: 71   ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
              + +   D+G Y C+A+NS G+ R +   L V          P +          L C 
Sbjct: 3378 PVYPQ---DSGYYLCQASNSAGSDR-QGRELRVFE-PPTIAPGPSNLTLTVHTQATLPC- 3431

Query: 131  PPRGSPEPNVYWKKNGQTLLFDGDSRMH-LVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
              RGSP+P+V WKKNGQTL  D     + L+   +LV+ D    D  +++C+  N AG  
Sbjct: 3432 EARGSPKPHVVWKKNGQTLSLDRHQEAYRLLPSSSLVLTDPDLQDTAQFECLVSNDAGET 3491

Query: 190  ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249
               +  + +++ P +     D      + V   C   G P P V W +            
Sbjct: 3492 RR-LFWVTVYVPPTIADDRTDFTVTKMAPVVLTCHTTGVPTPVVSWSKGGAQLGKRGSGY 3550

Query: 250  KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
            +V   G+L ++  +    G Y+C A N+ G       L V    +  LS   + +
Sbjct: 3551 RVSPTGALEIEQALPIHTGRYTCTARNAAGVAHKHVILMVQGTGAQILSSGQLRI 3605



 Score = 93.1 bits (221), Expect = 4e-17
 Identities = 98/338 (28%), Positives = 138/338 (40%), Gaps = 34/338 (10%)

Query: 30   TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
            +L C +   P P I WYK G LV  D    +L  G L  +  T      D+G Y C ATN
Sbjct: 2351 SLECESWAMPPPTITWYKDGQLVSPDNRLHLLADGRLLQINPTKAW---DSGRYLCVATN 2407

Query: 90   SYGTA-RSRNATLHVAVL-------REEFRLEP----------ESKQSAQGDTVVLECLP 131
              G   +  N  + V  +        E F +            E ++  + +   L C  
Sbjct: 2408 VAGEDDKDFNVLVQVPPIFQKIGDPNEAFEVHHQEEELRGGVLEYREIVENNPAYLYC-D 2466

Query: 132  PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
                P P + W K+ Q L  D +    L  G  L I   R  DAGRY C A N  G  E 
Sbjct: 2467 TNAVPPPQLTWYKDDQPLS-DIEGISVLQGGRVLQIPMVRSEDAGRYTCKASNEVG--ED 2523

Query: 192  AIATLKIHIKPYLITG-PEDVVAQT----GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
             +    + + P +I G PE++V +      S+V  QC+  G P P + W R+ G   +P 
Sbjct: 2524 WLHYELLVLTPPVIQGDPEELVEEVTVNANSTVNLQCQALGTPTPVISWLRN-GLPFIPS 2582

Query: 247  GRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
             + + L+DG  L++     AD   Y C AENS G+      L V    ++ L P     +
Sbjct: 2583 SKHQALEDGQVLQVSVADAADSASYMCVAENSAGSSEKLFTLKVQGTHTLQL-PRPKPSD 2641

Query: 306  SGNVARFTCTATGRPEPTMFWSVEGNRTI-IFPGMSRD 342
            +G          GR +  +  SV    TI   PG  RD
Sbjct: 2642 TGTYTCEALNVAGRDQKLVLLSVFAPPTIKQTPGGQRD 2679



 Score = 89.0 bits (211), Expect = 7e-16
 Identities = 98/337 (29%), Positives = 140/337 (41%), Gaps = 36/337 (10%)

Query: 17   QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD--THRSILPAGGLFFLRATHG 74
            +P  + V    P +L+C   G P P I W K G+LV +D  +   I   G L +L     
Sbjct: 2020 EPRTLAVTEGHPVSLSCECWGIPFPKITWKKDGMLVPTDGGSTEPISAVGRLLYLGKAQ- 2078

Query: 75   RVHSDAGVYWCEATNSYG-TARSRNATLHVAVL---REEFRLEPESKQSAQGDTVVLECL 130
               S  G Y CE +N  G +++ ++  ++VA       +F  E     S +   V LEC 
Sbjct: 2079 --PSQEGNYTCECSNIAGNSSQEQHLEVYVAPKVPGSSDFHKEVSVIHSGE---VTLEC- 2132

Query: 131  PPRGSPEPNVYWKKNGQTLLFD-GDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
               G P P V W+K+GQ +  D G    H   G  L ++ AR   AGRY CIA N AG  
Sbjct: 2133 EATGKPPPVVTWEKDGQLVTRDQGLLLQH--RGRALQVEQARAAHAGRYTCIAENEAGRA 2190

Query: 190  ESAIATLKIHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
            E       +     LI    G E +    G  V F    GG  L     +   GG  M L
Sbjct: 2191 EQRFDLSVLGNPSPLIRWFRGEEPI--SPGEDVYF--LAGGRILKLTRVQEEEGGLYMCL 2246

Query: 247  GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
                +L+     +     +  G YSC A NSV   +    L+V     + +    +N + 
Sbjct: 2247 ANGSLLE-----ILQANFSSSGHYSCIASNSVSEKTKHYKLSVLGTHGLQI----LNAQE 2297

Query: 307  GNVARFTCTATGR-PEPTMFWSVEGNRTIIFPGMSRD 342
             +  R+TC  T    E    + VE    +I P +S+D
Sbjct: 2298 QDAGRYTCVVTNEVGEAVKNYHVE---VLIPPSISKD 2331



 Score = 86.2 bits (204), Expect = 5e-15
 Identities = 103/358 (28%), Positives = 146/358 (40%), Gaps = 57/358 (15%)

Query: 59   SILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ 118
            S+L   GL  L A       DAG Y C  TN  G A  +N  + V +     + +P  + 
Sbjct: 2283 SVLGTHGLQILNAQE----QDAGRYTCVVTNEVGEA-VKNYHVEVLIPPSISKDDPLDEF 2337

Query: 119  SAQ------GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDAR 171
            S +        T+ LEC      P P + W K+GQ  L   D+R+HL+ DG  L I   +
Sbjct: 2338 SVKEVKAKVNSTLSLEC-ESWAMPPPTITWYKDGQ--LVSPDNRLHLLADGRLLQINPTK 2394

Query: 172  QTDAGRYQCIARNAAGTRESAIATLKIHIKPYL--ITGPEDVV-------AQTGSSVTFQ 222
              D+GRY C+A N AG  +     L + + P    I  P +            G  + ++
Sbjct: 2395 AWDSGRYLCVATNVAGEDDKDFNVL-VQVPPIFQKIGDPNEAFEVHHQEEELRGGVLEYR 2453

Query: 223  -----------CRVGGDPLPDVLWRRSAGGGNMPLGRVK---VLDDGS-LRLDNVILADE 267
                       C     P P + W +     + PL  ++   VL  G  L++  V   D 
Sbjct: 2454 EIVENNPAYLYCDTNAVPPPQLTWYKD----DQPLSDIEGISVLQGGRVLQIPMVRSEDA 2509

Query: 268  GEYSCEAENSVGAVSASGYLTVYDPPSINLSP----NSVNVESGNVARFTCTATGRPEPT 323
            G Y+C+A N VG       L V  PP I   P      V V + +     C A G P P 
Sbjct: 2510 GRYTCKASNEVGEDWLHYELLVLTPPVIQGDPEELVEEVTVNANSTVNLQCQALGTPTPV 2569

Query: 324  MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381
            + W   G      P +   K+   A+ DG  VL ++  D  DS  + +C A N AGSS
Sbjct: 2570 ISWLRNG-----LPFIPSSKHQ--ALEDG-QVLQVSVADAADSA-SYMCVAENSAGSS 2618



 Score = 82.6 bits (195), Expect = 6e-14
 Identities = 67/226 (29%), Positives = 96/226 (42%), Gaps = 15/226 (6%)

Query: 250  KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309
            ++L  G LR+      D G Y C A+N  G       L V  PP I    + ++   G+ 
Sbjct: 3596 QILSSGQLRISRASAEDAGNYLCIAKNPSGTALGKTRLVVQVPPVIKGGHSDLSAAEGSQ 3655

Query: 310  ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
            A   C A G PEP + W  +G    + P M   KY  T    G   L + ++++ D+  T
Sbjct: 3656 ALLPCIAQGIPEPHITWKKDG---FVVPSM-EGKY--TIQPSG--ELLVKNSERRDA-GT 3706

Query: 370  IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
              C A N AG +  R  L++ S      P  T  P + +L         CTA  +P P I
Sbjct: 3707 YTCIAENAAGHTSRRVHLSILS-----LPTFTTLPGDLSLNHGDRLWLRCTARGSPTPHI 3761

Query: 430  AWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
            +W      L++          TL    + + DSGTYTC A +  GK
Sbjct: 3762 SWMVNNR-LVKEGVLEQDGGSTLQRAAVTREDSGTYTCWAENIVGK 3806



 Score = 77.0 bits (181), Expect = 3e-12
 Identities = 87/343 (25%), Positives = 127/343 (37%), Gaps = 49/343 (14%)

Query: 165  LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP-------EDVVAQTGS 217
            L I +A++ DAGRY C+  N  G        +++ I P +           ++V A+  S
Sbjct: 2290 LQILNAQEQDAGRYTCVVTNEVGEAVKNYH-VEVLIPPSISKDDPLDEFSVKEVKAKVNS 2348

Query: 218  SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA-DEGEYSCEAEN 276
            +++ +C     P P + W +  G    P  R+ +L DG L   N   A D G Y C A N
Sbjct: 2349 TLSLECESWAMPPPTITWYKD-GQLVSPDNRLHLLADGRLLQINPTKAWDSGRYLCVATN 2407

Query: 277  SVGAVSASGYLTVYDPPSINL--SPNSV------------------NVESGNVARFTCTA 316
              G       + V  PP       PN                     +   N A   C  
Sbjct: 2408 VAGEDDKDFNVLVQVPPIFQKIGDPNEAFEVHHQEEELRGGVLEYREIVENNPAYLYCDT 2467

Query: 317  TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
               P P + W  +        G+S        V  G  VL I      D+     C A N
Sbjct: 2468 NAVPPPQLTWYKDDQPLSDIEGIS--------VLQGGRVLQIPMVRSEDA-GRYTCKASN 2518

Query: 377  YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ----TLPIKSMAVFPCTAICTPEPIIAWY 432
              G  ++  +L V +     PP+I   P       T+   S     C A+ TP P+I+W 
Sbjct: 2519 EVGEDWLHYELLVLT-----PPVIQGDPEELVEEVTVNANSTVNLQCQALGTPTPVISWL 2573

Query: 433  FEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
              G   I + +     DG  L +   D +DS +Y CVA +  G
Sbjct: 2574 RNGLPFIPSSKHQALEDGQVLQVSVADAADSASYMCVAENSAG 2616



 Score = 67.7 bits (158), Expect = 2e-09
 Identities = 65/241 (26%), Positives = 101/241 (41%), Gaps = 22/241 (9%)

Query: 238  SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
            ++ G +  L  +KV    +L+L     +D G Y+CEA N  G       L+V+ PP+I  
Sbjct: 2613 NSAGSSEKLFTLKVQGTHTLQLPRPKPSDTGTYTCEALNVAGRDQKLVLLSVFAPPTIKQ 2672

Query: 298  SP----NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
            +P    ++  V  G+ A   C +   PEP + W   G +      ++ D+   T + DG 
Sbjct: 2673 TPGGQRDTTVVRVGDTAVLHCESDTLPEPVITWYKNGQQ------IALDQQVQT-LLDGQ 2725

Query: 354  TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP--I 411
             +  +N   +   +    C   N  G +     L V     + PPI  N P  +TL    
Sbjct: 2726 KLEIVN--VQVADKGLYSCKVSNIVGEAIRTFVLIV-----QVPPIFEN-PEKETLSQVA 2777

Query: 412  KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN-VTNDGTLVLKDLDKSDSGTYTCVAS 470
             +  V  C     P P + W  +   +  +  R  V+  G L L  L  S  GTYTCVA 
Sbjct: 2778 GNPLVLVCDVAGVPAPTVTWLKDRMPVESSVERGVVSRGGRLQLSRLQPSQEGTYTCVAE 2837

Query: 471  S 471
            +
Sbjct: 2838 N 2838



 Score = 64.9 bits (151), Expect = 1e-08
 Identities = 54/207 (26%), Positives = 82/207 (39%), Gaps = 9/207 (4%)

Query: 23   VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
            +  + PA L C     P P + WYK    +      S+L  G +  +         DAG 
Sbjct: 2455 IVENNPAYLYCDTNAVPPPQLTWYKDDQPLSDIEGISVLQGGRVLQIPMVRSE---DAGR 2511

Query: 83   YWCEATNSYGT--ARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
            Y C+A+N  G          L   V++ +     E        TV L+C    G+P P +
Sbjct: 2512 YTCKASNEVGEDWLHYELLVLTPPVIQGDPEELVEEVTVNANSTVNLQC-QALGTPTPVI 2570

Query: 141  YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
             W +NG   +        L DG  L +  A   D+  Y C+A N+AG+ E  + TLK+  
Sbjct: 2571 SWLRNGLPFI-PSSKHQALEDGQVLQVSVADAADSASYMCVAENSAGSSEK-LFTLKVQ- 2627

Query: 201  KPYLITGPEDVVAQTGSSVTFQCRVGG 227
              + +  P    + TG+       V G
Sbjct: 2628 GTHTLQLPRPKPSDTGTYTCEALNVAG 2654



 Score = 53.2 bits (122), Expect = 4e-05
 Identities = 68/268 (25%), Positives = 105/268 (39%), Gaps = 42/268 (15%)

Query: 248  RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN-------LSPN 300
            ++ VL    L++ N    D G Y+C   N VG    + ++ V  PPSI+        S  
Sbjct: 2281 KLSVLGTHGLQILNAQEQDAGRYTCVVTNEVGEAVKNYHVEVLIPPSISKDDPLDEFSVK 2340

Query: 301  SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
             V  +  +     C +   P PT+ W  +G   ++ P    ++ H  A  DG  +L IN 
Sbjct: 2341 EVKAKVNSTLSLECESWAMPPPTITWYKDGQ--LVSPD---NRLHLLA--DG-RLLQINP 2392

Query: 361  TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN-GPSNQTLPI-------- 411
            T   DS    +C A N AG       + V     + PPI    G  N+   +        
Sbjct: 2393 TKAWDS-GRYLCVATNVAGEDDKDFNVLV-----QVPPIFQKIGDPNEAFEVHHQEEELR 2446

Query: 412  -----------KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS 460
                        + A   C     P P + WY + + L      +V   G ++   + +S
Sbjct: 2447 GGVLEYREIVENNPAYLYCDTNAVPPPQLTWYKDDQPLSDIEGISVLQGGRVLQIPMVRS 2506

Query: 461  -DSGTYTCVASSRHGKYVWSGALLVDSP 487
             D+G YTC AS+  G+      LLV +P
Sbjct: 2507 EDAGRYTCKASNEVGEDWLHYELLVLTP 2534



 Score = 49.6 bits (113), Expect = 5e-04
 Identities = 47/159 (29%), Positives = 67/159 (42%), Gaps = 15/159 (9%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P     P D+++       L C A GSP+P I W     LV       +   GG    RA
Sbjct: 3730 PTFTTLPGDLSLNHGDRLWLRCTARGSPTPHISWMVNNRLVKEGV---LEQDGGSTLQRA 3786

Query: 72   THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ---SAQGDTVVLE 128
               R   D+G Y C A N  G  ++  + +HV   +E   L+ E+        GD+  L+
Sbjct: 3787 AVTR--EDSGTYTCWAENIVGKVQA-VSFVHV---KEAPALQGEASSHLVELLGDSARLD 3840

Query: 129  CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVI 167
            C   RG P P + W K+G  +L       H +  G+L I
Sbjct: 3841 C-AARGDPAPVIRWIKDGLPVL--SSHHKHQLQNGSLAI 3876



 Score = 46.0 bits (104), Expect = 0.006
 Identities = 30/91 (32%), Positives = 41/91 (45%), Gaps = 5/91 (5%)

Query: 5    YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPA 63
            +VT    P I +   D TV +  P  L C   G P+P + W KGG  L    +   + P 
Sbjct: 3496 WVTVYVPPTIADDRTDFTVTKMAPVVLTCHTTGVPTPVVSWSKGGAQLGKRGSGYRVSPT 3555

Query: 64   GGLFFLRATHGRVHSDAGVYWCEATNSYGTA 94
            G L   +A    +H+  G Y C A N+ G A
Sbjct: 3556 GALEIEQAL--PIHT--GRYTCTARNAAGVA 3582



 Score = 41.9 bits (94), Expect = 0.10
 Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 6/89 (6%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
            V  G+   ++E+   VTV  +    L C+A G+P+P I W + G+  +  +    L  G 
Sbjct: 2536 VIQGDPEELVEE---VTVNANSTVNLQCQALGTPTPVISWLRNGLPFIPSSKHQALEDGQ 2592

Query: 66   LFFLRATHGRVHSDAGVYWCEATNSYGTA 94
            +  +        +D+  Y C A NS G++
Sbjct: 2593 VLQVSVADA---ADSASYMCVAENSAGSS 2618


>UniRef50_UPI00004D4C52 Cluster: Roundabout homolog 4 precursor
           (Magic roundabout).; n=1; Xenopus tropicalis|Rep:
           Roundabout homolog 4 precursor (Magic roundabout). -
           Xenopus tropicalis
          Length = 986

 Score =  166 bits (404), Expect = 3e-39
 Identities = 87/193 (45%), Positives = 114/193 (59%), Gaps = 8/193 (4%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT----HRSI--LPAGG 65
           P IIE P D+ V + +PATL CRA G+P P I WY+ G  V + T     RS   LP G 
Sbjct: 6   PRIIEHPSDLFVKKDKPATLYCRAEGNPQPTIEWYRNGEHVETSTDDKTQRSYVQLPEGP 65

Query: 66  LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
           LFF      +  SD G+Y C A N  GTA SRNA+L+VA LR++FRL P     A G  +
Sbjct: 66  LFFFSLNQRKGKSDEGIYTCVARNHLGTAFSRNASLYVAALRDDFRLNPSDAVVAVGKQL 125

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
            +ECLPP+G PEPNV WKK+G  +  + ++  + +  G L I  A +TD+G Y C+A N 
Sbjct: 126 EIECLPPKGHPEPNVTWKKDG--IPINHNNSRYTISAGKLFIGKALKTDSGLYSCLASNQ 183

Query: 186 AGTRESAIATLKI 198
            G RES  A + +
Sbjct: 184 VGERESRAAKIVV 196



 Score = 78.2 bits (184), Expect = 1e-12
 Identities = 87/320 (27%), Positives = 141/320 (44%), Gaps = 24/320 (7%)

Query: 636 VELIEATPIDSKTIKLMWEILNFY-YLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEI 694
           V L   T + S ++ + W++L    + EG  +++R L +   E+   T    N+ S   I
Sbjct: 212 VHLDNITALPSASVYVHWQVLTESPFTEGYSVFYRTLSSTESEWTEWTKSRINEYSTV-I 270

Query: 695 TSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILN--TTTVHLKW 752
            SL +  KYEF + PF  K  G  SN +  +  ++VP+  P NI +  +     T+ + W
Sbjct: 271 PSLWRGQKYEFKIRPFAGKNYGPDSNIKHLRIPEEVPNIAPQNINVTAVEGGNGTIVVSW 330

Query: 753 SPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT-SLIMTNLTSGVSYSVQIA 811
            PP   + +  I GY V   W     N++    +  V + T SL +  L SG+ Y VQ+A
Sbjct: 331 EPPPKNIHSSNIKGYKV---WCF--ENETHPKADWIVDEETKSLEIPMLASGIKYQVQVA 385

Query: 812 AETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETWFYFLIGAIVLF 871
           A    G+G  S   Y  IDS  V    +    +  E+ +     V    F   +G +   
Sbjct: 386 AINDAGIGMPSIPKYIMIDSPEV--KEVKDENIYFELIL---QVVRHPAFIGTVGTVAWI 440

Query: 872 KIIVIAGIIYVRKYNIFAKK--SALPNI---YDSNGTSLVTQMNIKAAVSLSH--PLTSC 924
            ++V A  +  R    ++ K  S L N    + S  T +  +M+I  +  LSH     SC
Sbjct: 441 LLMVAAVYVCQRHSKRYSTKQHSILGNSLYRFASEDTIIKHRMDISDSPWLSHTWKSASC 500

Query: 925 YN--KNTVTKTESLLWMENQ 942
                +T++    LLW E +
Sbjct: 501 SRNYSSTISMNSQLLWSETK 520



 Score = 63.3 bits (147), Expect = 4e-08
 Identities = 45/156 (28%), Positives = 69/156 (44%), Gaps = 11/156 (7%)

Query: 134 GSPEPNVYWKKNGQTLLFDGDSR-----MHLVDGGNLVI---QDARQTDAGRYQCIARNA 185
           G+P+P + W +NG+ +    D +     + L +G        Q   ++D G Y C+ARN 
Sbjct: 31  GNPQPTIEWYRNGEHVETSTDDKTQRSYVQLPEGPLFFFSLNQRKGKSDEGIYTCVARNH 90

Query: 186 AGTRESAIATLKIH-IKPYLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGN 243
            GT  S  A+L +  ++      P D V   G  +  +C    G P P+V W++     N
Sbjct: 91  LGTAFSRNASLYVAALRDDFRLNPSDAVVAVGKQLEIECLPPKGHPEPNVTWKKDGIPIN 150

Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279
               R  +   G L +   +  D G YSC A N VG
Sbjct: 151 HNNSRYTI-SAGKLFIGKALKTDSGLYSCLASNQVG 185



 Score = 60.1 bits (139), Expect = 4e-07
 Identities = 45/188 (23%), Positives = 74/188 (39%), Gaps = 10/188 (5%)

Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
           PP I   P+ + V+    A   C A G P+PT+ W   G            + +      
Sbjct: 5   PPRIIEHPSDLFVKKDKPATLYCRAEGNPQPTIEWYRNGEHVETSTDDKTQRSYVQLPEG 64

Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK---LTVTSDDDRPPPIITNGPSNQT 408
            +   ++N            C A N+ G++F R     +    DD R        PS+  
Sbjct: 65  PLFFFSLNQRKGKSDEGIYTCVARNHLGTAFSRNASLYVAALRDDFRL------NPSDAV 118

Query: 409 LPIKSMAVFPCTAICT-PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
           + +       C      PEP + W  +G  +  N+ R   + G L +    K+DSG Y+C
Sbjct: 119 VAVGKQLEIECLPPKGHPEPNVTWKKDGIPINHNNSRYTISAGKLFIGKALKTDSGLYSC 178

Query: 468 VASSRHGK 475
           +AS++ G+
Sbjct: 179 LASNQVGE 186


>UniRef50_Q7Z5N4 Cluster: Protein sidekick-1 precursor; n=62;
           Euteleostomi|Rep: Protein sidekick-1 precursor - Homo
           sapiens (Human)
          Length = 2213

 Score =  165 bits (401), Expect = 6e-39
 Identities = 214/823 (26%), Positives = 320/823 (38%), Gaps = 89/823 (10%)

Query: 22  TVARHQPATLNCRAGGS-PSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
           TV++ + A LN     S P P + W++ G  ++     +I     L  L  T     SDA
Sbjct: 201 TVSQGRAAILNLLPITSYPRPQVTWFREGHKIIPSNRIAITLENQLVILATTT----SDA 256

Query: 81  GVYWCEATNSYGTARSRNATLHVAVLREEFRLE--------PESKQS--AQGDTVVLECL 130
           G Y+ +A N        +  +H+++ R+    E        P   +S  A      LEC+
Sbjct: 257 GAYYVQAVNEKNGENKTSPFIHLSIARDVGTPETMAPTIVVPPGNRSVVAGSSETTLECI 316

Query: 131 -PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
              R   + +V WK+NG  +     S +H   G +L I +    D G Y C A       
Sbjct: 317 ASARPVEDLSVTWKRNGVRI----TSGLHSF-GRHLTISNPTSADTGPYVCEAALPGSAF 371

Query: 190 ESAIATLKIHI--KPYLITGPED-VVAQTGSSVTFQCRVGGDPLPDVLWRRSA-GGGNMP 245
           E A AT  + I   PY    PE  + A+   +V   C+  G PLP + W + A     + 
Sbjct: 372 EPARATAFLFIIEPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQ 431

Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLSPNSVNV 304
             R KVL  G LR+  +   D G + C A N  G +    YL V +  P     P    V
Sbjct: 432 NPRYKVLASGGLRIQKLRPEDSGIFQCFASNEGGEIQTHTYLDVTNIAPVFTQRPVDTTV 491

Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
             G  A   C  +G P+P + W  E +  I+  G  R          G+ +  +   D  
Sbjct: 492 TDGMTAILRCEVSGAPKPAITWKRENH--ILASGSVRIPRFMLLESGGLQIAPVFIQDAG 549

Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
           +      C A N  GS      LTV +        I + P +  +   + A   C A   
Sbjct: 550 N----YTCYAANTEGSLNASATLTVWNRTS-----IVHPPEDHVVIKGTTATLHCGATHD 600

Query: 425 PEPII--AWYFEGEALI--QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
           P   +   W  +  AL      R  V  DG+L++      D G Y+C   S  G      
Sbjct: 601 PRVSLRYVWKKDNVALTPSSTSRIVVEKDGSLLISQTWSGDIGDYSCEIVSEGGNDSRMA 660

Query: 481 AL-LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQ 539
            L +++ P +P           +L   P    +H     +V LSW +    G+S IL Y 
Sbjct: 661 RLEVIELPHSP----------QNLLVSPNSSHSH-----AVVLSWVRPFD-GNSPILYYI 704

Query: 540 VEVFSRETLSGNNTPRNSRGWVVIARRV--HQTHYVVKSLIPGITYMFIVRTENSHGLSG 597
           VE      LS N++P     W V    V    T   V  L P  TY F V   N  G   
Sbjct: 705 VE------LSENSSP-----WKVHLSNVGPEMTGVTVSGLTPARTYQFRVCAVNEVGRGQ 753

Query: 598 PSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILN 657
            S  +  + + ++  S      V++    R N     I+   +  P          E  +
Sbjct: 754 YSAETSRLMLPEEPPSAPPKNIVASG---RTN---QSIMVQWQPPP----------ETEH 797

Query: 658 FYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGK 717
              L G  + +R L  +  EY+ + I  S +V+   +T L  +T+YE  +  +     G 
Sbjct: 798 NGVLRGYILRYR-LAGLPGEYQQRNIT-SPEVNYCLVTDLIIWTQYEIQVAAYNGAGLGV 855

Query: 718 PSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVP 777
            S +    TL  VP  PP N++   +N+TT+   W+PP  Q  NGI  GY ++    D P
Sbjct: 856 FSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADAP 915

Query: 778 ANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGP 820
              ++V I    H      +TNL    +Y   +   T  G GP
Sbjct: 916 EAVTVVTIAPDFHGVHHGHITNLKKFTAYFTSVLCFTTPGDGP 958



 Score =  124 bits (300), Expect = 1e-26
 Identities = 94/322 (29%), Positives = 142/322 (44%), Gaps = 16/322 (4%)

Query: 11  APYIIEQPLDVTV-ARHQPATLNCRAGGSPSP--AIRWYKGGVLVVSDTHRSILPAGGLF 67
           AP I+  P + +V A     TL C A   P    ++ W + GV + S  H        L 
Sbjct: 292 APTIVVPPGNRSVVAGSSETTLECIASARPVEDLSVTWKRNGVRITSGLHSF---GRHLT 348

Query: 68  FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ-GDTV 125
               T     +D G Y CEA           AT  + ++    F  EPES+ SA+  +TV
Sbjct: 349 ISNPTS----ADTGPYVCEAALPGSAFEPARATAFLFIIEPPYFTAEPESRISAEVEETV 404

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
            + C    G P P + W K+  ++    + R  ++  G L IQ  R  D+G +QC A N 
Sbjct: 405 DIGC-QAMGVPLPTLQWYKDAISISRLQNPRYKVLASGGLRIQKLRPEDSGIFQCFASNE 463

Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS---AGGG 242
            G  ++       +I P     P D     G +   +C V G P P + W+R       G
Sbjct: 464 GGEIQTHTYLDVTNIAPVFTQRPVDTTVTDGMTAILRCEVSGAPKPAITWKRENHILASG 523

Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
           ++ + R  +L+ G L++  V + D G Y+C A N+ G+++AS  LTV++  SI   P   
Sbjct: 524 SVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAANTEGSLNASATLTVWNRTSIVHPPEDH 583

Query: 303 NVESGNVARFTCTATGRPEPTM 324
            V  G  A   C AT  P  ++
Sbjct: 584 VVIKGTTATLHCGATHDPRVSL 605



 Score =  118 bits (285), Expect = 7e-25
 Identities = 110/421 (26%), Positives = 185/421 (43%), Gaps = 34/421 (8%)

Query: 10  EAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGL 66
           E PY   +P   ++    +   + C+A G P P ++WYK  + +  + +    +L +GGL
Sbjct: 384 EPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQNPRYKVLASGGL 443

Query: 67  FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
              +        D+G++ C A+N  G  ++ +  L V  +   F   P       G T +
Sbjct: 444 RIQKLRP----EDSGIFQCFASNEGGEIQT-HTYLDVTNIAPVFTQRPVDTTVTDGMTAI 498

Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH---LVDGGNLVIQDARQTDAGRYQCIAR 183
           L C    G+P+P + WK+    +L  G  R+    L++ G L I      DAG Y C A 
Sbjct: 499 LRC-EVSGAPKPAITWKRENH-ILASGSVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAA 556

Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV--LWRR-SAG 240
           N  G+  +A ATL +  +  ++  PED V   G++ T  C    DP   +  +W++ +  
Sbjct: 557 NTEGSL-NASATLTVWNRTSIVHPPEDHVVIKGTTATLHCGATHDPRVSLRYVWKKDNVA 615

Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV----YDPPSIN 296
                  R+ V  DGSL +      D G+YSCE  +  G  S    L V    + P ++ 
Sbjct: 616 LTPSSTSRIVVEKDGSLLISQTWSGDIGDYSCEIVSEGGNDSRMARLEVIELPHSPQNLL 675

Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
           +SPNS +     V  +     G   P +++ VE     +    S  K H + V   +T +
Sbjct: 676 VSPNSSH-SHAVVLSWVRPFDGN-SPILYYIVE-----LSENSSPWKVHLSNVGPEMTGV 728

Query: 357 TINDTDKNDSRNTIVCSAVNYAGS---SFVRGKLTVTSDDDRPPP--IITNGPSNQTLPI 411
           T++      +    VC AVN  G    S    +L +  +    PP  I+ +G +NQ++ +
Sbjct: 729 TVSGLTPARTYQFRVC-AVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIMV 787

Query: 412 K 412
           +
Sbjct: 788 Q 788



 Score =  101 bits (243), Expect = 9e-20
 Identities = 108/427 (25%), Positives = 162/427 (37%), Gaps = 40/427 (9%)

Query: 79  DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
           DAG Y C   N  G    R + + VA +   F    + K  +QG   +L  LP    P P
Sbjct: 163 DAGFYRCVVRNRMGALLQRKSEVQVAYMGS-FMDTDQRKTVSQGRAAILNLLPITSYPRP 221

Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY--QCIARNAAGTRESAIATL 196
            V W + G  ++    +R+ +     LVI     +DAG Y  Q +       + S    L
Sbjct: 222 QVTWFREGHKII--PSNRIAITLENQLVILATTTSDAGAYYVQAVNEKNGENKTSPFIHL 279

Query: 197 KIH--------IKPYLITGPEDVVAQTGSS-VTFQCRVGGDPLPD--VLWRRSAGGGNMP 245
            I         + P ++  P +     GSS  T +C     P+ D  V W+R+  G  + 
Sbjct: 280 SIARDVGTPETMAPTIVVPPGNRSVVAGSSETTLECIASARPVEDLSVTWKRN--GVRIT 337

Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAE---NSVGAVSASGYLTVYDPPSINLSPNS- 301
            G         L + N   AD G Y CEA    ++     A+ +L + +PP     P S 
Sbjct: 338 SGLHSF--GRHLTISNPTSADTGPYVCEAALPGSAFEPARATAFLFIIEPPYFTAEPESR 395

Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
           ++ E        C A G P PT+ W  +    I    +   +Y   A   G+ +  +   
Sbjct: 396 ISAEVEETVDIGCQAMGVPLPTLQWYKDA---ISISRLQNPRYKVLAS-GGLRIQKLRPE 451

Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
           D         C A N  G       L VT+      P+ T  P + T+     A+  C  
Sbjct: 452 DSG----IFQCFASNEGGEIQTHTYLDVTNI----APVFTQRPVDTTVTDGMTAILRCEV 503

Query: 422 ICTPEPIIAWYFEGEAL----IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
              P+P I W  E   L    ++  R  +   G L +  +   D+G YTC A++  G   
Sbjct: 504 SGAPKPAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAANTEGSLN 563

Query: 478 WSGALLV 484
            S  L V
Sbjct: 564 ASATLTV 570



 Score = 74.5 bits (175), Expect = 2e-11
 Identities = 87/382 (22%), Positives = 155/382 (40%), Gaps = 37/382 (9%)

Query: 110 FRLEPESKQ-SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ 168
           F+ EP   Q   +G+ +VL CL     P    + + + +   +  + +         +I 
Sbjct: 106 FKTEPGLPQIHLEGNRLVLTCLAEGSWPLEFKWMRDDSELTTYSSEYKY--------IIP 157

Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGG 227
             ++ DAG Y+C+ RN  G      + +++ ++  ++ T     V+Q  +++     +  
Sbjct: 158 SLQKLDAGFYRCVVRNRMGALLQRKSEVQVAYMGSFMDTDQRKTVSQGRAAILNLLPITS 217

Query: 228 DPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSV-GAVSASGY 286
            P P V W R  G   +P  R+ +  +  L +     +D G Y  +A N   G    S +
Sbjct: 218 YPRPQVTWFRE-GHKIIPSNRIAITLENQLVILATTTSDAGAYYVQAVNEKNGENKTSPF 276

Query: 287 L------TVYDP----PSINLSPNSVNVESGNV-ARFTCTATGRPEPTMFWSVEGNRTII 335
           +       V  P    P+I + P + +V +G+      C A+ RP   +  + + N   I
Sbjct: 277 IHLSIARDVGTPETMAPTIVVPPGNRSVVAGSSETTLECIASARPVEDLSVTWKRNGVRI 336

Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395
             G+     H          LTI++    D+    VC A    GS+F   + T       
Sbjct: 337 TSGLHSFGRH----------LTISNPTSADT-GPYVCEAA-LPGSAFEPARATAFLFIIE 384

Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL--IQNHRRNVTNDGTLV 453
           PP       S  +  ++      C A+  P P + WY +  ++  +QN R  V   G L 
Sbjct: 385 PPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQNPRYKVLASGGLR 444

Query: 454 LKDLDKSDSGTYTCVASSRHGK 475
           ++ L   DSG + C AS+  G+
Sbjct: 445 IQKLRPEDSGIFQCFASNEGGE 466



 Score = 66.5 bits (155), Expect = 4e-09
 Identities = 53/187 (28%), Positives = 86/187 (45%), Gaps = 10/187 (5%)

Query: 637  ELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNIT-IEYEMKT-ILHSNDVSGFEI 694
            E + A  + S  I L W  +      GL + ++ L     ++ E ++ I+  N      +
Sbjct: 1281 ENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFRAKDLDPEPRSHIVRGNHTQSALL 1340

Query: 695  TSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQ-TLDDVPDGPPINIEMFILNTTTVHLKWS 753
              LRK+  YE  ++ F +   G PS   + + T DD P GPP+ +    +  T+V + W 
Sbjct: 1341 AGLRKFVLYELQVLAFTRIGNGVPSTPLILERTKDDAP-GPPVRLVFPEVRLTSVRIVWQ 1399

Query: 754  PPELQLQNGIITGYNVVVNWL-DVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAA 812
            PPE    NGII GY +        P   + V +  TV Q T+   T+L    +Y  +++A
Sbjct: 1400 PPE--EPNGIILGYQIAYRLASSSPHTFTTVEVGATVRQFTA---TDLAPESAYIFRLSA 1454

Query: 813  ETIIGLG 819
            +T  G G
Sbjct: 1455 KTRQGWG 1461



 Score = 58.4 bits (135), Expect = 1e-06
 Identities = 49/187 (26%), Positives = 93/187 (49%), Gaps = 14/187 (7%)

Query: 639  IEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILH-SNDVSGFE---I 694
            ++   ++S TI+ +W      ++ G+   ++ L       E  T++  + D  G     I
Sbjct: 876  VQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADAPEAVTVVTIAPDFHGVHHGHI 935

Query: 695  TSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSP 754
            T+L+K+T Y   ++ F    +G PS  ++  T +D P G   ++    +  T++ + W  
Sbjct: 936  TNLKKFTAYFTSVLCFTTPGDGPPSTPQLVWTQEDKP-GAVGHLSFTEILDTSLKVSWQE 994

Query: 755  PELQLQNGIITGYNVVVNWLDVPANKSMV--AINTTVHQATSLIMTNLTSGVSYSVQIAA 812
            P L+ +NGIITGY   ++W     N S +   +N+T H+     +  L+S  +Y++ +AA
Sbjct: 995  P-LE-KNGIITGYQ--ISWEVYGRNDSRLTHTLNSTTHEYK---IQGLSSLTTYTIDVAA 1047

Query: 813  ETIIGLG 819
             T +G G
Sbjct: 1048 VTAVGTG 1054



 Score = 58.4 bits (135), Expect = 1e-06
 Identities = 83/336 (24%), Positives = 140/336 (41%), Gaps = 39/336 (11%)

Query: 504  PGPPTKPITHN--VTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV 561
            P PP + +     VT  S+ L W   +  G+S I  + ++V  RE       PR    W 
Sbjct: 1477 PAPPRELLVPQAEVTARSLRLQWVPGSD-GASPIRYFTMQV--REL------PRGE--WQ 1525

Query: 562  VIARRV-HQ-THYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTG 619
              +  + H+ T  VV  L P  +Y   ++  N  G S  S  +++VT   D     E  G
Sbjct: 1526 TYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPG--EPPG 1583

Query: 620  VSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLE-----GLFIYFRPLDN- 673
              ++T +  + +      LI+  P   +++  + +    YY E     G     + L N 
Sbjct: 1584 SVSATPHTTSSV------LIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNP 1637

Query: 674  ------ITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTL 727
                  +T +   KT+  S+  +  E+T L+KY +YE  +   Y      P+++ V   +
Sbjct: 1638 IALHAELTAQSSFKTVNSSSTSTMCELTHLKKYRRYEVIMTA-YNIIGESPASAPVEVFV 1696

Query: 728  DDV-PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN 786
             +  P   P N+++  L  + + + W PP  + QNG I GY +   W +  +      + 
Sbjct: 1697 GEAAPAMAPQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYY-W-EADSQNETEKMK 1754

Query: 787  TTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFS 822
                    + + NLTS   Y V I+A    G GP S
Sbjct: 1755 VLFLPEPVVRLKNLTSHTKYLVSISAFNAAGDGPKS 1790



 Score = 53.2 bits (122), Expect = 4e-05
 Identities = 44/182 (24%), Positives = 81/182 (44%), Gaps = 10/182 (5%)

Query: 639  IEATPIDSKTIKLMWEI----LNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEI 694
            ++ TP+ +  +++ W+          ++G  IY+   D+     +MK +     V    +
Sbjct: 1708 VQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPV--VRL 1765

Query: 695  TSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSP 754
             +L  +TKY   +  F    +G  S+ +  +T    P G P  +    + +TT+++ W  
Sbjct: 1766 KNLTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAP-GAPSFLAFSEITSTTLNVSWGE 1824

Query: 755  PELQLQNGIITGYNVVVNWL-DVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAE 813
            P     NGI+ GY VV   L  V     +V +    +    L + +LT GV+Y  ++ A 
Sbjct: 1825 PAAA--NGILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQAR 1882

Query: 814  TI 815
            TI
Sbjct: 1883 TI 1884



 Score = 51.6 bits (118), Expect = 1e-04
 Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 4/129 (3%)

Query: 692  FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751
            F I  L ++ +YE  +  F     G  S     +T + VP   P N+    +++T + L 
Sbjct: 1237 FTIEELEEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILLT 1296

Query: 752  WSPPELQLQNGIITGYNVVVNWLDV-PANKSMVAINTTVHQATSLIMTNLTSGVSYSVQI 810
            W+    Q QNG+I GY ++    D+ P  +S +      +   S ++  L   V Y +Q+
Sbjct: 1297 WTSVPEQDQNGLILGYKILFRAKDLDPEPRSHIVRG---NHTQSALLAGLRKFVLYELQV 1353

Query: 811  AAETIIGLG 819
             A T IG G
Sbjct: 1354 LAFTRIGNG 1362



 Score = 50.0 bits (114), Expect = 4e-04
 Identities = 34/139 (24%), Positives = 60/139 (43%), Gaps = 3/139 (2%)

Query: 688 DVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTL-DDVPDGPPINIEMFILNTT 746
           +++G  ++ L     Y+F +    +   G+ S       L ++ P  PP NI        
Sbjct: 724 EMTGVTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQ 783

Query: 747 TVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSY 806
           ++ ++W PP     NG++ GY +      +P        N T  +    ++T+L     Y
Sbjct: 784 SIMVQWQPPPETEHNGVLRGYILRYRLAGLPGEYQQ--RNITSPEVNYCLVTDLIIWTQY 841

Query: 807 SVQIAAETIIGLGPFSQKV 825
            +Q+AA    GLG FS+ V
Sbjct: 842 EIQVAAYNGAGLGVFSRAV 860



 Score = 48.0 bits (109), Expect = 0.002
 Identities = 37/140 (26%), Positives = 57/140 (40%), Gaps = 3/140 (2%)

Query: 688  DVSGFEITSLRKYTKYEFFL--IPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNT 745
            D    EI +L  YT Y F +  +         PS SRV QTL   PD  P ++ +   + 
Sbjct: 1129 DAQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPS-SRVIQTLQAPPDVAPTSVTVRTASE 1187

Query: 746  TTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVS 805
            T++ L+W P      NG        + +       S VA   +        +  L   + 
Sbjct: 1188 TSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWME 1247

Query: 806  YSVQIAAETIIGLGPFSQKV 825
            Y +Q+ A   +G GP+S+ V
Sbjct: 1248 YELQMQAFNAVGAGPWSEVV 1267



 Score = 46.4 bits (105), Expect = 0.005
 Identities = 73/352 (20%), Positives = 133/352 (37%), Gaps = 32/352 (9%)

Query: 504  PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
            PGPP + +   V  TSV + W Q  +  +  ILGYQ+    R   S  +T       V +
Sbjct: 1378 PGPPVRLVFPEVRLTSVRIVW-QPPEEPNGIILGYQIAY--RLASSSPHTFTT----VEV 1430

Query: 564  ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNS 623
               V Q  +    L P   Y+F +  +   G   P                 E T ++  
Sbjct: 1431 GATVRQ--FTATDLAPESAYIFRLSAKTRQGWGEPL----------------EATVITTE 1472

Query: 624  TEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTI 683
               R     + +V   E T   +++++L W   +       +   +  +    E++  + 
Sbjct: 1473 KRERPAPPRELLVPQAEVT---ARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQTYSS 1529

Query: 684  LHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGK-PSNSRVAQTLDDVPDGPPINIEMFI 742
              S++ +   +  LR +T Y+  L       +    S +    TL DVP  PP ++    
Sbjct: 1530 SISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATP 1589

Query: 743  LNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTS 802
              T++V ++W PP  +  NG++ GY +    L+  A     A   T+    +L    LT+
Sbjct: 1590 HTTSSVLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEA--KTLKNPIAL-HAELTA 1646

Query: 803  GVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGD 854
              S+    ++ T         K Y   +      +++   P +  V +  G+
Sbjct: 1647 QSSFKTVNSSSTSTMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGE 1698


>UniRef50_Q8TD84 Cluster: Down syndrome cell adhesion molecule-like
            protein 1 precursor; n=63; Euteleostomi|Rep: Down
            syndrome cell adhesion molecule-like protein 1 precursor
            - Homo sapiens (Human)
          Length = 2053

 Score =  164 bits (399), Expect = 1e-38
 Identities = 207/832 (24%), Positives = 340/832 (40%), Gaps = 74/832 (8%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P  I    ++T    +   +NCR  G P  +I+WYK  +L+  D HR ++   G   L+ 
Sbjct: 505  PPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLL-PDNHRQVVFENGT--LKL 561

Query: 72   THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
            T  +   D G Y C        + S++  +HVAV         E   ++ G  + + C+ 
Sbjct: 562  TDVQKGMDEGEYLCSVLIQPQLSISQS--VHVAVKVPPLIQPFEFPPASIGQLLYIPCVV 619

Query: 132  PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRE 190
              G     + W+K+GQ ++      +   +   +L I        G Y CIA NAA T  
Sbjct: 620  SSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAAT-V 678

Query: 191  SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN------M 244
            S    L + + P  +  P +     G +    C V G P P V+W+ + G GN      +
Sbjct: 679  SRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPV 738

Query: 245  PL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSV 302
            PL GR+++L + SL + +V+  D G Y C+A N VG  +S S +LTV  P  I   PN+ 
Sbjct: 739  PLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSHPNTT 798

Query: 303  NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG----VTVLTI 358
                G+     CTA G     + W  E   T+I P   R   +A A  D     V+ L +
Sbjct: 799  IAIKGHAKELNCTARGERPIIIRW--EKGDTVIDP--DRVMRYAIATKDNGDEVVSTLKL 854

Query: 359  NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
               D+ DS     C A+N  G      +LTV    D PP +       +++ ++    F 
Sbjct: 855  KPADRGDS-VFFSCHAINSYGEDRGLIQLTVQEPPD-PPELEIREVKARSMNLRWTQRFD 912

Query: 419  CTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGK 475
              +I T   I           +   RN++   N   +V  DL  +   +    + ++ G+
Sbjct: 913  GNSIITGFDIEYKNKSDSWDFKQSTRNISPTINQANIV--DLHPASVYSIRMYSFNKIGR 970

Query: 476  YVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK-IGSSS 534
               S  L +            + + ++  GPP       VT  S+ ++W    K + +  
Sbjct: 971  SEPSKELTI------------STEEAAPDGPPMDVTLQPVTSQSIQVTWKAPKKELQNGV 1018

Query: 535  ILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHG 594
            I GYQ+    RE   G+N        V +        Y + +L     Y  +V+  N  G
Sbjct: 1019 IRGYQIGY--RENSPGSN---GQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAG 1073

Query: 595  LSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWE 654
             +GPS    + T  +D  S             R   +T  +  +  + P  S        
Sbjct: 1074 -TGPSSSEINATTLEDVPS-------QPPENVRALSITSDVAVISWSEPPRS-------- 1117

Query: 655  ILNFYYLEGLFIYFRPLDNITIEY-EMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKK 713
             LN   L+G  + F  L  +  E+ EM+ I  + +    E+  + K+T Y   ++ + + 
Sbjct: 1118 TLN-GVLKGYRVIFWSL-YVDGEWGEMQNITTTRE--RVELRGMEKFTNYSVQVLAYTQA 1173

Query: 714  FEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNW 773
             +G  S+    QT +DVP GPP  I+    + ++V + W PP     NG+I  Y +  + 
Sbjct: 1174 GDGVRSSVLYIQTKEDVP-GPPAGIKAVPSSASSVVVSWLPP--TKPNGVIRKYTIFCS- 1229

Query: 774  LDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
                + +   +   T  +     + +L  G  Y + +AA T  G G  S+KV
Sbjct: 1230 -SPGSGQPAPSEYETSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNSSEKV 1280



 Score =  141 bits (341), Expect = 1e-31
 Identities = 135/524 (25%), Positives = 224/524 (42%), Gaps = 47/524 (8%)

Query: 9   GEAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAGGL 66
           G + Y +   L  VT +      + C A GSPS A+RWY   G  +    H   + A G 
Sbjct: 22  GTSLYFVNDSLQQVTFSSSVGVVVPCPAAGSPSAALRWYLATGDDIYDVPHIRHVHANGT 81

Query: 67  FFL-----RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
             L      A +  +H +   Y+C A N+ G  RS N  +  AV RE + +  E ++S +
Sbjct: 82  LQLYPFSPSAFNSFIHDND--YFCTAENAAGKIRSPNIRVK-AVFREPYTVRVEDQRSMR 138

Query: 122 GDTVVLECLPPRGSPE--PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRY 178
           G+  V +CL P    E    V W+K+  +++   + R  +   G L I D ++ DA   Y
Sbjct: 139 GNVAVFKCLIPSSVQEYVSVVSWEKDTVSII--PEHRFFITYHGGLYISDVQKEDALSTY 196

Query: 179 QCIARN--AAGTRESAIATLKI----HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
           +CI ++  +  TR+S  A L +       P ++ G        G +V   C   G P+P 
Sbjct: 197 RCITKHKYSGETRQSNGARLSVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPA 256

Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
           + W +   G  +P           L + ++   D G Y CE  N+ G+  A+G L V DP
Sbjct: 257 IRWLKD--GRPLPADSRWTKRITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVIDP 314

Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
             + L+P  +    G+    +C  TG PE T+ W    N  ++ P    D+  +      
Sbjct: 315 LHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRW--YRNTELVLP----DEAISIRGLSN 368

Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
            T+L I    K+ S     C A   A ++       + + +D  P I+++       P +
Sbjct: 369 ETLL-ITSAQKSHS-GAYQCFATRKAQTA---QDFAIIALEDGTPRIVSSFSEKVVNPGE 423

Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQ--NHRRN--VTNDGTLV----LKDLDKSDSGT 464
             ++  C A   P P + W  + E +++  +HR N    +DGT +    +      D G 
Sbjct: 424 QFSLM-CAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGV 482

Query: 465 YTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPT 508
           Y C A +  G   +   + V  P  P+I   R  +++++ G  T
Sbjct: 483 YRCTARNLVGSAEYQARINVRGP--PSIRAMR--NITAVAGRDT 522



 Score =  132 bits (319), Expect = 6e-29
 Identities = 207/850 (24%), Positives = 335/850 (39%), Gaps = 109/850 (12%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-THRS---ILPAGGLF 67
            P I+    +  V   +  +L C A G+P P + W      +V D +HR+    +  G   
Sbjct: 408  PRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTI 467

Query: 68   FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
                  G    D GVY C A N  G+A  + A ++V       R        A  DT++ 
Sbjct: 468  SHMNVTGPQIRDGGVYRCTARNLVGSAEYQ-ARINVRG-PPSIRAMRNITAVAGRDTLI- 524

Query: 128  ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ-TDAGRYQC--IARN 184
             C    G P  ++ W K+   LL   + R  + + G L + D ++  D G Y C  + + 
Sbjct: 525  NCRVI-GYPYYSIKWYKDA--LLLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQP 581

Query: 185  AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRRSA---- 239
                 +S    +K+   P LI   E   A  G  +   C V    +P  + WR+      
Sbjct: 582  QLSISQSVHVAVKV---PPLIQPFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVII 638

Query: 240  GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
             G  + +   + +   SL++ +V L   G Y+C A N+   VS    L V  PP   + P
Sbjct: 639  SGSGVTIESKEFMS--SLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPPRFVVQP 696

Query: 300  NSVNVESGNVARFTCTATGRPEPTMFWS-VEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
            N+ +   G      C+  G P P + W   +G+        +  +YH   +   + +L  
Sbjct: 697  NNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSG-------NPQQYHPVPLTGRIQILPN 749

Query: 359  NDT----DKNDSRNTIVCSAVNYAGSSFVRGK-LTVTSDDDRPPPIITNGPSNQTLPIKS 413
            +         +     +C A N  G+   +   LTV     + P +IT+ P N T+ IK 
Sbjct: 750  SSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTV-----KIPAMITSHP-NTTIAIKG 803

Query: 414  MA-VFPCTAICTPEPIIAWYFEGEALIQNHR----RNVTND------GTLVLKDLDKSDS 462
             A    CTA     PII  + +G+ +I   R       T D       TL LK  D+ DS
Sbjct: 804  HAKELNCTA-RGERPIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDS 862

Query: 463  GTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTL 522
              ++C A + +G+      L V  P                P PP   I   V   S+ L
Sbjct: 863  VFFSCHAINSYGEDRGLIQLTVQEP----------------PDPPELEI-REVKARSMNL 905

Query: 523  SWSQNNKIGSSSILGYQVEVFSR-ETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGI 581
             W+Q    G+S I G+ +E  ++ ++     + RN      I+  ++Q + V   L P  
Sbjct: 906  RWTQRFD-GNSIITGFDIEYKNKSDSWDFKQSTRN------ISPTINQANIV--DLHPAS 956

Query: 582  TYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEA 641
             Y   + + N  G S P   S  +T+               STE       D     +  
Sbjct: 957  VYSIRMYSFNKIGRSEP---SKELTI---------------STE---EAAPDGPPMDVTL 995

Query: 642  TPIDSKTIKLMWEI----LNFYYLEGLFIYFRP-LDNITIEYEMKTILHSNDVSGFEITS 696
             P+ S++I++ W+     L    + G  I +R        +Y +  +  + D   + + +
Sbjct: 996  QPVTSQSIQVTWKAPKKELQNGVIRGYQIGYRENSPGSNGQYSIVEMKATGDSEVYTLDN 1055

Query: 697  LRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPE 756
            L+K+ +Y   +  F +   G  S+   A TL+DVP  PP N+    + +    + WS P 
Sbjct: 1056 LKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPENVRALSITSDVAVISWSEPP 1115

Query: 757  LQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETII 816
                NG++ GY V+   L V      +   TT  +   L    +    +YSVQ+ A T  
Sbjct: 1116 RSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTTRERVEL--RGMEKFTNYSVQVLAYTQA 1173

Query: 817  GLGPFSQKVY 826
            G G  S  +Y
Sbjct: 1174 GDGVRSSVLY 1183



 Score =  118 bits (285), Expect = 7e-25
 Identities = 156/610 (25%), Positives = 242/610 (39%), Gaps = 41/610 (6%)

Query: 43  IRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG--TARSRNAT 100
           + W K  V ++ +    I   GGL+    +  +       Y C   + Y   T +S  A 
Sbjct: 159 VSWEKDTVSIIPEHRFFITYHGGLYI---SDVQKEDALSTYRCITKHKYSGETRQSNGAR 215

Query: 101 LHVAVLREEFRLEPESKQSAQ---GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM 157
           L V    E      +   S +   G TV L C    G P P + W K+G+ L    DSR 
Sbjct: 216 LSVTDPAESIPTILDGFHSQEVWAGHTVELPCTAS-GYPIPAIRWLKDGRPL--PADSRW 272

Query: 158 HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT-GPEDVVAQTG 216
                G L I D R  D+G Y C   N  G+ E A   L + I P  +T  P+ +    G
Sbjct: 273 TKRITG-LTISDLRTEDSGTYICEVTNTFGSAE-ATGILMV-IDPLHVTLTPKKLKTGIG 329

Query: 217 SSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDGSLRLDNVILADEGEYSCEA 274
           S+V   C + G P   + W R+     +P   + +  L + +L + +   +  G Y C A
Sbjct: 330 STVILSCALTGSPEFTIRWYRNTELV-LPDEAISIRGLSNETLLITSAQKSHSGAYQCFA 388

Query: 275 ENSVGAVSASGYLTVYD-PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRT 333
                       + + D  P I  S +   V  G      C A G P PT+ W+++ +  
Sbjct: 389 TRKAQTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALD-DEP 447

Query: 334 IIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV-CSAVNYAGSSFVRGKLTVTSD 392
           I+  G  R   +  +  DG T+  +N T        +  C+A N  GS+  + ++ V   
Sbjct: 448 IVRDGSHRTNQYTMS--DGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINV--- 502

Query: 393 DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTL 452
             R PP I     N T       +  C  I  P   I WY +   L  NHR+ V  +GTL
Sbjct: 503 --RGPPSI-RAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDNHRQVVFENGTL 559

Query: 453 VLKDLDKS-DSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI 511
            L D+ K  D G Y C    +    + S ++ V   + P I  F     +S+      P 
Sbjct: 560 KLTDVQKGMDEGEYLCSVLIQPQLSI-SQSVHVAVKVPPLIQPFEFPP-ASIGQLLYIPC 617

Query: 512 THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLS----GNNTPRNSRGWVVIARRV 567
             +  D  + ++W    K G   I G  V + S+E +S     + + +++  +  IA   
Sbjct: 618 VVSSGDMPIRITW---RKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNA 674

Query: 568 HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD-SVTVGDDSNSLWE-GTGVSNSTE 625
             T    + LI  +   F+V+  N  G+ G + V + SV        +W+   G  N  +
Sbjct: 675 AATVSRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQ 734

Query: 626 YRNNILTDHI 635
           Y    LT  I
Sbjct: 735 YHPVPLTGRI 744



 Score = 92.3 bits (219), Expect = 7e-17
 Identities = 119/466 (25%), Positives = 189/466 (40%), Gaps = 47/466 (10%)

Query: 31  LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
           L+C   GSP   IRWY+   LV+ D   SI        L  +  + HS  G Y C AT  
Sbjct: 334 LSCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHS--GAYQCFATRK 391

Query: 91  YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
             TA+   A + +             K    G+   L C   +G+P P V W  + + ++
Sbjct: 392 AQTAQDF-AIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAA-KGAPPPTVTWALDDEPIV 449

Query: 151 FDGDSRMH---LVDG---GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK-PY 203
            DG  R +   + DG    ++ +   +  D G Y+C ARN  G+ E      +I+++ P 
Sbjct: 450 RDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQA---RINVRGPP 506

Query: 204 LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNV 262
            I    ++ A  G      CRV G P   + W + A    +P   R  V ++G+L+L +V
Sbjct: 507 SIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDAL--LLPDNHRQVVFENGTLKLTDV 564

Query: 263 ILA-DEGEYSCEAENSVG-AVSASGYLTVYDPPSIN---LSPNSVNVESGNVARFTCTAT 317
               DEGEY C        ++S S ++ V  PP I      P S+    G +    C  +
Sbjct: 565 QKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFEFPPASI----GQLLYIPCVVS 620

Query: 318 GRPEPTMF-WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
               P    W  +G   I   G++ +        + ++ L I+      + N   C A N
Sbjct: 621 SGDMPIRITWRKDGQVIISGSGVTIESK------EFMSSLQISSVSLKHNGN-YTCIASN 673

Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-YFEG 435
            A +     +L V     R PP     P+NQ        V  C+    P P + W + +G
Sbjct: 674 AAATVSRERQLIV-----RVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKG 728

Query: 436 EALIQNH-------RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
               Q +       R  +  + +L+++ + + D G Y C AS+  G
Sbjct: 729 SGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVG 774



 Score = 61.3 bits (142), Expect = 2e-07
 Identities = 43/186 (23%), Positives = 79/186 (42%), Gaps = 8/186 (4%)

Query: 677  EYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPI 736
            +++  T   S  ++   I  L   + Y   +  F K    +PS      T +  PDGPP+
Sbjct: 932  DFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPM 991

Query: 737  NIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLI 796
            ++ +  + + ++ + W  P+ +LQNG+I GY +     + P +    +I        S +
Sbjct: 992  DVTLQPVTSQSIQVTWKAPKKELQNGVIRGYQIGYR-ENSPGSNGQYSIVEMKATGDSEV 1050

Query: 797  MT--NLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGD 854
             T  NL     Y V + A    G GP S ++     + +   D+ S+ P N     +  D
Sbjct: 1051 YTLDNLKKFAQYGVVVQAFNRAGTGPSSSEI-----NATTLEDVPSQPPENVRALSITSD 1105

Query: 855  FVMETW 860
              + +W
Sbjct: 1106 VAVISW 1111



 Score = 51.6 bits (118), Expect = 1e-04
 Identities = 63/241 (26%), Positives = 102/241 (42%), Gaps = 35/241 (14%)

Query: 373  SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
            +AV  AG      K+T+      P  II+ G +  T  +K + + PC ++  P P + W 
Sbjct: 1266 AAVTSAGRGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRL-PCNSVGDPAPAVKWT 1324

Query: 433  FEGE-----ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
             + E       +  HR   TN GTL+L+ +   DSG YTC A++  G       LLV  P
Sbjct: 1325 KDSEDSAIPVSMDGHRLIHTN-GTLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVP 1383

Query: 488  INPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRET 547
                            P  P   ++   + +S+TL+W   +  G SSI G+ ++ +S + 
Sbjct: 1384 ----------------PDQPRLTVS-KTSASSITLTWIPGDN-GGSSIRGFVLQ-YSVD- 1423

Query: 548  LSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
                    NS  W  +     +  + + SL  G  Y   +  +NS G    S + ++ T 
Sbjct: 1424 --------NSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGRISEIIEAKTH 1475

Query: 608  G 608
            G
Sbjct: 1476 G 1476



 Score = 43.2 bits (97), Expect = 0.044
 Identities = 31/90 (34%), Positives = 43/90 (47%), Gaps = 9/90 (10%)

Query: 8    SGEAPY-IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK----GGVLVVSDTHRSILP 62
            +G+AP  II     VT    +   L C + G P+PA++W K      + V  D HR ++ 
Sbjct: 1285 AGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHR-LIH 1343

Query: 63   AGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
              G   LRA       D+G Y C ATN+ G
Sbjct: 1344 TNGTLLLRAVKA---EDSGYYTCTATNTGG 1370



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 3/78 (3%)

Query: 219  VTFQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAE 275
            V   C   GDP P V W + +    +P+   G   +  +G+L L  V   D G Y+C A 
Sbjct: 1307 VRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTAT 1366

Query: 276  NSVGAVSASGYLTVYDPP 293
            N+ G  +    L V  PP
Sbjct: 1367 NTGGFDTIIVNLLVQVPP 1384



 Score = 37.5 bits (83), Expect = 2.2
 Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 10/99 (10%)

Query: 134  GSPEPNVYWKKNGQT----LLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
            G P P V W K+ +     +  DG   +H    G L+++  +  D+G Y C A N  G  
Sbjct: 1315 GDPAPAVKWTKDSEDSAIPVSMDGHRLIHT--NGTLLLRAVKAEDSGYYTCTATNTGGF- 1371

Query: 190  ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228
            ++ I  L + + P     P   V++T +S      + GD
Sbjct: 1372 DTIIVNLLVQVPP---DQPRLTVSKTSASSITLTWIPGD 1407


>UniRef50_UPI0000DB7011 Cluster: PREDICTED: similar to CG33519-PB
            isoform 1; n=1; Apis mellifera|Rep: PREDICTED: similar to
            CG33519-PB isoform 1 - Apis mellifera
          Length = 2794

 Score =  164 bits (398), Expect = 1e-38
 Identities = 156/619 (25%), Positives = 251/619 (40%), Gaps = 53/619 (8%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG-GLFFLRATHGRVHS 78
            DV +   +P  L  +    P+P ++W+K G+ +        +    G+  LR    R   
Sbjct: 898  DVKIVVGEPLKLEAQVVAFPNPEVQWFKNGIPLRQTKEMYFINEPIGIIGLRIDSCRPE- 956

Query: 79   DAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
            DAG Y    +NS G T  +    +     R EF +  +     +G    +E +   G P 
Sbjct: 957  DAGTYSMTVSNSLGETTGTAKVEIEEKERRPEFVVNLQPLSVMEGFPAKME-VKVLGKPT 1015

Query: 138  PNVYWKKNGQTLLFDGD--SRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRE---- 190
            P + W KNG+ ++ DG     + + DG   L+I+ A   DAG YQ IA N  GT      
Sbjct: 1016 PRLQWFKNGEEIVPDGKRVKAVSMADGSQALIIEKATPEDAGEYQVIAGNTEGTSSCKGT 1075

Query: 191  -SAIATLKIHI---KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
             S +  L+  +   KP  +    DV  + G  +       G+P+PDV W +  G    P 
Sbjct: 1076 ISVVGKLQSDVSEQKPGFVNPMRDVYVEEGQPLNLSVSFVGNPIPDVNWSKD-GAPLQPS 1134

Query: 247  GRVKVLDDGS---LRLDNVILADEGEYSCEAENSVG---AVSASGYLTVYDPPSINLSPN 300
             R  +  DG    L ++     D G Y C   N +G     S +    ++ PPS   +  
Sbjct: 1135 DRFTITCDGKKTELEINPCEGKDAGVYECRISNPLGEDSTRSTANVRKIFQPPSFIHAFK 1194

Query: 301  SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
             +       A+F    +G P P + W V   + I+      DKY      D    L + D
Sbjct: 1195 DLQQLPTFDAKFLARVSGVPRPDITWYVN-EKPIV---QDDDKYKIKRDGDACC-LYVKD 1249

Query: 361  TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR----PPPIITNGPSNQTLPIKSMAV 416
               +DS     C AVN  G +     LT+  +  +     PP       +  +     A 
Sbjct: 1250 CTYDDS-GVYKCRAVNKGGEAECAANLTIVDEIGKIQKFEPPSFLKRIGDCEMYKGMPAK 1308

Query: 417  FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLV---LKDLDKSDSGTYTCVASSRH 473
            F       PEP   W+  G+ + Q  R  +  +G+L+   + ++D+ D+G YT   S+ H
Sbjct: 1309 FTACVTGIPEPDFEWFHNGDKMWQTDRIRMDQEGSLLRLTINNVDELDAGKYTLKISNPH 1368

Query: 474  GKYVWSGALLVDS-------PINPNIHFFRAADVSSLPGP-PTKPITHNVTDTSVTLSWS 525
            G+   +  L+ ++        +      F     S +P P   +PI   + D  +TLSW 
Sbjct: 1369 GEDSCTADLIYETLEPRAKKSLGDQYADFDKYRKSGIPLPLADRPIISRMMDRHLTLSWK 1428

Query: 526  QNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMF 585
             +  IGS   + YQ+E+   E   G+        W      +      +++L P   Y F
Sbjct: 1429 PSIPIGSRIPVTYQIEMC--ELPDGD--------WFTARTGIRSCVCDIRNLEPFRDYKF 1478

Query: 586  IVRTENSHGLSGPSPVSDS 604
             +R EN +G+S PSP + +
Sbjct: 1479 RIRVENKYGISDPSPYAQT 1497



 Score =  113 bits (271), Expect = 4e-23
 Identities = 123/521 (23%), Positives = 209/521 (40%), Gaps = 36/521 (6%)

Query: 34   RAGGSPSPAIRWYKGGVLVVSDTHRSIL---PAGGLFFLRATHGRVHSDAGVYWCEATNS 90
            R  G P P ++W +    +  D    I+       +  + +      SD G   C A+N 
Sbjct: 716  RCSGIPRPNLKWLRCNEEIREDDRYKIVIQEDGNNVESVCSITTFCPSDVGKITCRASNI 775

Query: 91   YGTARSRNATLHVAVLREEF-RLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
            YG+A++ +  L V ++   F  L P+S +  +G  + L+     GSP P + W K+G+ +
Sbjct: 776  YGSAQT-SCDLLVQLITPSFVNLLPKSTEVDEGGCLELKA-KIDGSPMPEISWYKDGEKI 833

Query: 150  LFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGTRES--AIATLKIHIKPYLI 205
            + D  +R+ ++  G   L+I   +  D G Y+ +  N+ G + S  A+A      KP   
Sbjct: 834  VPDEHTRIEILPDGTTKLIIDCVQPLDCGAYKLVINNSTGEQSSLCAVAIKPERRKPSFS 893

Query: 206  TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK---VLDDG----SLR 258
               EDV    G  +  + +V   P P+V W ++     +PL + K    +++      LR
Sbjct: 894  KSLEDVKIVVGEPLKLEAQVVAFPNPEVQWFKN----GIPLRQTKEMYFINEPIGIIGLR 949

Query: 259  LDNVILADEGEYSCEAENSVGAVSASGYLTVYDP---PSINLSPNSVNVESGNVARFTCT 315
            +D+    D G YS    NS+G  + +  + + +    P   ++   ++V  G  A+    
Sbjct: 950  IDSCRPEDAGTYSMTVSNSLGETTGTAKVEIEEKERRPEFVVNLQPLSVMEGFPAKMEVK 1009

Query: 316  ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
              G+P P + W   G    I P   R K  A ++ DG   L I      D+    V  A 
Sbjct: 1010 VLGKPTPRLQWFKNGEE--IVPDGKRVK--AVSMADGSQALIIEKATPEDAGEYQVI-AG 1064

Query: 376  NYAGSSFVRGKLTVT----SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431
            N  G+S  +G ++V     SD     P   N   +  +          + +  P P + W
Sbjct: 1065 NTEGTSSCKGTISVVGKLQSDVSEQKPGFVNPMRDVYVEEGQPLNLSVSFVGNPIPDVNW 1124

Query: 432  YFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPI 488
              +G  L  + R  +T DG    L +   +  D+G Y C  S+  G+        V    
Sbjct: 1125 SKDGAPLQPSDRFTITCDGKKTELEINPCEGKDAGVYECRISNPLGEDSTRSTANVRKIF 1184

Query: 489  NPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
             P        D+  LP    K +          ++W  N K
Sbjct: 1185 QPPSFIHAFKDLQQLPTFDAKFLARVSGVPRPDITWYVNEK 1225



 Score =  106 bits (254), Expect = 4e-21
 Identities = 131/473 (27%), Positives = 183/473 (38%), Gaps = 44/473 (9%)

Query: 31   LNCRAGGSPSPAIRWYKGGVLVVSDTHR--SILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
            L  +  GSP P I WYK G  +V D H    ILP G    +      +  D G Y     
Sbjct: 812  LKAKIDGSPMPEISWYKDGEKIVPDEHTRIEILPDGTTKLIIDCVQPL--DCGAYKLVIN 869

Query: 89   NSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
            NS G   S  A       R+  F    E  +   G+ + LE       P P V W KNG 
Sbjct: 870  NSTGEQSSLCAVAIKPERRKPSFSKSLEDVKIVVGEPLKLEA-QVVAFPNPEVQWFKNGI 928

Query: 148  TLLFDGDSRMHLVDGG----NLVIQDARQTDAGRYQCIARNAAG--TRESAIATLKIHIK 201
             L       M+ ++       L I   R  DAG Y     N+ G  T  + +   +   +
Sbjct: 929  PL--RQTKEMYFINEPIGIIGLRIDSCRPEDAGTYSMTVSNSLGETTGTAKVEIEEKERR 986

Query: 202  PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLD--DGS-- 256
            P  +   + +    G     + +V G P P + W ++ G   +P G RVK +   DGS  
Sbjct: 987  PEFVVNLQPLSVMEGFPAKMEVKVLGKPTPRLQWFKN-GEEIVPDGKRVKAVSMADGSQA 1045

Query: 257  LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS---PNSVN------VESG 307
            L ++     D GEY   A N+ G  S  G ++V      ++S   P  VN      VE G
Sbjct: 1046 LIIEKATPEDAGEYQVIAGNTEGTSSCKGTISVVGKLQSDVSEQKPGFVNPMRDVYVEEG 1105

Query: 308  NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG-VTVLTINDTDKNDS 366
                 + +  G P P + WS +G      P    D++  T   DG  T L IN  +  D+
Sbjct: 1106 QPLNLSVSFVGNPIPDVNWSKDG-----APLQPSDRF--TITCDGKKTELEINPCEGKDA 1158

Query: 367  RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
                 C   N  G    R    V     +PP  I      Q LP    A F       P 
Sbjct: 1159 -GVYECRISNPLGEDSTRSTANVRK-IFQPPSFIHAFKDLQQLPTFD-AKFLARVSGVPR 1215

Query: 427  PIIAWYFEGEALIQ-NHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGK 475
            P I WY   + ++Q + +  +  DG    L +KD    DSG Y C A ++ G+
Sbjct: 1216 PDITWYVNEKPIVQDDDKYKIKRDGDACCLYVKDCTYDDSGVYKCRAVNKGGE 1268



 Score = 93.9 bits (223), Expect = 2e-17
 Identities = 94/340 (27%), Positives = 130/340 (38%), Gaps = 28/340 (8%)

Query: 17   QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR--SILPAGGLFFLRATHG 74
            QPL  +V    PA +  +  G P+P ++W+K G  +V D  R  ++  A G   L     
Sbjct: 994  QPL--SVMEGFPAKMEVKVLGKPTPRLQWFKNGEEIVPDGKRVKAVSMADGSQAL-IIEK 1050

Query: 75   RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR- 133
                DAG Y   A N+ GT+  +     V  L+ +   +     +   D  V E  P   
Sbjct: 1051 ATPEDAGEYQVIAGNTEGTSSCKGTISVVGKLQSDVSEQKPGFVNPMRDVYVEEGQPLNL 1110

Query: 134  -----GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAA 186
                 G+P P+V W K+G  L    D      DG    L I      DAG Y+C   N  
Sbjct: 1111 SVSFVGNPIPDVNWSKDGAPLQ-PSDRFTITCDGKKTELEINPCEGKDAGVYECRISNPL 1169

Query: 187  G--TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
            G  +  S     KI   P  I   +D+         F  RV G P PD+ W  +      
Sbjct: 1170 GEDSTRSTANVRKIFQPPSFIHAFKDLQQLPTFDAKFLARVSGVPRPDITWYVNEKPIVQ 1229

Query: 245  PLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---------P 292
               + K+  DG    L + +    D G Y C A N  G    +  LT+ D         P
Sbjct: 1230 DDDKYKIKRDGDACCLYVKDCTYDDSGVYKCRAVNKGGEAECAANLTIVDEIGKIQKFEP 1289

Query: 293  PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332
            PS         +  G  A+FT   TG PEP   W   G++
Sbjct: 1290 PSFLKRIGDCEMYKGMPAKFTACVTGIPEPDFEWFHNGDK 1329



 Score = 89.8 bits (213), Expect = 4e-16
 Identities = 123/548 (22%), Positives = 200/548 (36%), Gaps = 46/548 (8%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWY-KGGVLVVSDTHRSILPAGGLFFLR 70
            P  IE   DV VA  +           P P I WY KG  +   D+   I         +
Sbjct: 494  PKFIETLQDVDVANGKSGMFKAMFTADPVPDITWYFKGDEIHSEDSRLKITVDNKPGSDK 553

Query: 71   ATHGRV--------HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122
             T   V          D G Y  +  N YG A S NA L++ +  E   L   +     G
Sbjct: 554  LTETTVTLSVPKCSKDDTGEYTLKLKNKYGEAES-NAFLNLLLCPEIQELNDVTTNV--G 610

Query: 123  DTVVLECLPPRGSPEPNVYWKKNGQTLL------FDGDSRMHLVDGGNLVIQDARQTDAG 176
            +++  + +  +G+P+P++ W K+G+ L       F+ D R +      LVI++    D G
Sbjct: 611  ESLAWQAII-KGNPKPDITWSKDGKVLEKGERYDFEEDKRNNKF---TLVIKEVEIDDKG 666

Query: 177  RYQCIARNAAGTRESAIATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVL 234
             YQ  A+N  G   +          P    I   + V  +  S V F+ R  G P P++ 
Sbjct: 667  AYQVTAKNYLGEASAQAILTPYSETPIFSEILPKKPVECKDRSDVEFKVRCSGIPRPNLK 726

Query: 235  WRR-SAGGGNMPLGRVKVLDDGS-----LRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
            W R +         ++ + +DG+       +     +D G+ +C A N  G+   S  L 
Sbjct: 727  WLRCNEEIREDDRYKIVIQEDGNNVESVCSITTFCPSDVGKITCRASNIYGSAQTSCDLL 786

Query: 289  VY--DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHA 346
            V    P  +NL P S  V+ G          G P P + W  +G +  I P    D++  
Sbjct: 787  VQLITPSFVNLLPKSTEVDEGGCLELKAKIDGSPMPEISWYKDGEK--IVP----DEHTR 840

Query: 347  TAVF-DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPS 405
              +  DG T L I+     D          N  G         V    +R  P  +    
Sbjct: 841  IEILPDGTTKLIIDCVQPLDC-GAYKLVINNSTGEQ--SSLCAVAIKPERRKPSFSKSLE 897

Query: 406  NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND--GTLVLK--DLDKSD 461
            +  + +          +  P P + W+  G  L Q       N+  G + L+       D
Sbjct: 898  DVKIVVGEPLKLEAQVVAFPNPEVQWFKNGIPLRQTKEMYFINEPIGIIGLRIDSCRPED 957

Query: 462  SGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVT 521
            +GTY+   S+  G+   +  + ++              +S + G P K     +   +  
Sbjct: 958  AGTYSMTVSNSLGETTGTAKVEIEEKERRPEFVVNLQPLSVMEGFPAKMEVKVLGKPTPR 1017

Query: 522  LSWSQNNK 529
            L W +N +
Sbjct: 1018 LQWFKNGE 1025



 Score = 79.4 bits (187), Expect = 6e-13
 Identities = 106/499 (21%), Positives = 191/499 (38%), Gaps = 32/499 (6%)

Query: 15   IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLFFLRATH 73
            I++  DVT    +         G+P P I W K G VL   + +          F     
Sbjct: 599  IQELNDVTTNVGESLAWQAIIKGNPKPDITWSKDGKVLEKGERYDFEEDKRNNKFTLVIK 658

Query: 74   GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
                 D G Y   A N  G A ++      +       + P+     +  + V   +   
Sbjct: 659  EVEIDDKGAYQVTAKNYLGEASAQAILTPYSETPIFSEILPKKPVECKDRSDVEFKVRCS 718

Query: 134  GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-----IQDARQTDAGRYQCIARNAAGT 188
            G P PN+ W +  + +  D   ++ + + GN V     I     +D G+  C A N  G+
Sbjct: 719  GIPRPNLKWLRCNEEIREDDRYKIVIQEDGNNVESVCSITTFCPSDVGKITCRASNIYGS 778

Query: 189  RESAIATLKIHIKPYLIT-GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP-- 245
             +++   L   I P  +   P+      G  +  + ++ G P+P++ W +  G   +P  
Sbjct: 779  AQTSCDLLVQLITPSFVNLLPKSTEVDEGGCLELKAKIDGSPMPEISWYKD-GEKIVPDE 837

Query: 246  LGRVKVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLSPN 300
              R+++L DG+ +L  D V   D G Y     NS G  S+   + +      PS + S  
Sbjct: 838  HTRIEILPDGTTKLIIDCVQPLDCGAYKLVINNSTGEQSSLCAVAIKPERRKPSFSKSLE 897

Query: 301  SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
             V +  G   +        P P + W   G    I    +++ Y       G+  L I D
Sbjct: 898  DVKIVVGEPLKLEAQVVAFPNPEVQWFKNG----IPLRQTKEMYFINEPI-GIIGLRI-D 951

Query: 361  TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN--QTLPIKSMAVFP 418
            + + +   T   +  N  G +    K+ +   + RP  ++   P +  +  P K M V  
Sbjct: 952  SCRPEDAGTYSMTVSNSLGETTGTAKVEIEEKERRPEFVVNLQPLSVMEGFPAK-MEV-- 1008

Query: 419  CTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGT--LVLKDLDKSDSGTYTCVASSRH 473
               +  P P + W+  GE ++ + +R       DG+  L+++     D+G Y  +A +  
Sbjct: 1009 -KVLGKPTPRLQWFKNGEEIVPDGKRVKAVSMADGSQALIIEKATPEDAGEYQVIAGNTE 1067

Query: 474  GKYVWSGALLVDSPINPNI 492
            G     G + V   +  ++
Sbjct: 1068 GTSSCKGTISVVGKLQSDV 1086



 Score = 70.5 bits (165), Expect = 3e-10
 Identities = 77/298 (25%), Positives = 118/298 (39%), Gaps = 18/298 (6%)

Query: 8    SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
            S + P  +    DV V   QP  L+    G+P P + W K G   +  + R  +   G  
Sbjct: 1087 SEQKPGFVNPMRDVYVEEGQPLNLSVSFVGNPIPDVNWSKDGA-PLQPSDRFTITCDGKK 1145

Query: 68   FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
                 +     DAGVY C  +N  G   +R +T +V  + +        K   Q  T   
Sbjct: 1146 TELEINPCEGKDAGVYECRISNPLGEDSTR-STANVRKIFQPPSFIHAFKDLQQLPTFDA 1204

Query: 128  ECLP-PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARN 184
            + L    G P P++ W  N + ++ D D      DG    L ++D    D+G Y+C A N
Sbjct: 1205 KFLARVSGVPRPDITWYVNEKPIVQDDDKYKIKRDGDACCLYVKDCTYDDSGVYKCRAVN 1264

Query: 185  AAGTRESA--------IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
              G  E A        I  ++    P  +    D     G    F   V G P PD  W 
Sbjct: 1265 KGGEAECAANLTIVDEIGKIQKFEPPSFLKRIGDCEMYKGMPAKFTACVTGIPEPDFEWF 1324

Query: 237  RSAGGGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
             + G       R+++  +GS   L ++NV   D G+Y+ +  N  G  S +  L +Y+
Sbjct: 1325 HN-GDKMWQTDRIRMDQEGSLLRLTINNVDELDAGKYTLKISNPHGEDSCTADL-IYE 1380



 Score = 62.5 bits (145), Expect = 7e-08
 Identities = 89/387 (22%), Positives = 143/387 (36%), Gaps = 37/387 (9%)

Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT---DAGRYQC 180
           T+V E +     P  +  W K+G+ L      R+ +   G     +  +    D G Y C
Sbjct: 412 TIVFE-VEATSLPRADAKWFKDGKPLR--SGERVRIESSGERFRMELSKIIIEDEGVYTC 468

Query: 181 IARNAAGTRES----AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
              N  G   +     + T+    +P  I   +DV    G S  F+     DP+PD+ W 
Sbjct: 469 SFSNKLGEDMTEGYLTVQTVDELRRPKFIETLQDVDVANGKSGMFKAMFTADPVPDITWY 528

Query: 237 RSAGGGNMPLGRVKVLDD---GSLRLDNVILA---------DEGEYSCEAENSVGAVSAS 284
                 +    R+K+  D   GS +L    +          D GEY+ + +N  G   ++
Sbjct: 529 FKGDEIHSEDSRLKITVDNKPGSDKLTETTVTLSVPKCSKDDTGEYTLKLKNKYGEAESN 588

Query: 285 GYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
            +L +   P I    N V    G    +     G P+P + WS +G   ++  G   D  
Sbjct: 589 AFLNLLLCPEIQ-ELNDVTTNVGESLAWQAIIKGNPKPDITWSKDGK--VLEKGERYDFE 645

Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404
                 +    L I + + +D +     +A NY G +  +  LT  S+      I+   P
Sbjct: 646 EDKR--NNKFTLVIKEVEIDD-KGAYQVTAKNYLGEASAQAILTPYSETPIFSEILPKKP 702

Query: 405 SNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT--NDGTLV-----LKDL 457
                  +S   F       P P + W    E + ++ R  +    DG  V     +   
Sbjct: 703 VE--CKDRSDVEFKVRCSGIPRPNLKWLRCNEEIREDDRYKIVIQEDGNNVESVCSITTF 760

Query: 458 DKSDSGTYTCVASSRHGKYVWSGALLV 484
             SD G  TC AS+ +G    S  LLV
Sbjct: 761 CPSDVGKITCRASNIYGSAQTSCDLLV 787



 Score = 51.6 bits (118), Expect = 1e-04
 Identities = 49/220 (22%), Positives = 88/220 (40%), Gaps = 30/220 (13%)

Query: 381  SFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ 440
            S+   +  + S  +   P     P  + +     A   C A+ +P+P+I WY     + +
Sbjct: 2212 SYAEAEAMLESKKEGHLPFFREKPQIKPIEEGKPAQLACLAVGSPKPLIQWYKNDMMVQE 2271

Query: 441  NHRRNVTND----GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFR 496
             +R  +T D      L      + D G+Y  VA +  G+ V      V + I   +  F 
Sbjct: 2272 TNRIKITEDQDGRSILSFNPTKEHDVGSYKVVARNSLGQTV------VRTRI---VEAF- 2321

Query: 497  AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556
                  +P  P  P   +V+DT + + W Q    G+S +L Y ++    +++        
Sbjct: 2322 ------VPSGPDSPELVDVSDTEILVRWKQPKHDGNSPVLCYNLQYKEGDSID------- 2368

Query: 557  SRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
               W+ IA  +    Y++++L    TY F +   N  G S
Sbjct: 2369 ---WIDIASNIDHEFYLIRNLKADTTYNFRLAARNRIGWS 2405



 Score = 50.4 bits (115), Expect = 3e-04
 Identities = 42/161 (26%), Positives = 63/161 (39%), Gaps = 6/161 (3%)

Query: 134  GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRES 191
            G P+P + +  N Q +   G         G   L I    + D G Y+ +A N  G    
Sbjct: 1571 GYPKPKMTYYFNDQPIESGGRYDQSYTRNGQATLFINRMLERDEGLYEAVASNEHGEARQ 1630

Query: 192  AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS---AGGGNMPLGR 248
             +  L+I   P  I  PE+ +           RV G P P++ W +        +     
Sbjct: 1631 RVC-LRIAEYPTFIHRPEETIVMIRRIGQLTARVTGVPYPEIKWYKDWKPLTTSSRIRIE 1689

Query: 249  VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
             K  D   L + + ++ DEG YS  A N  G++S S  L V
Sbjct: 1690 FKEPDTSLLIISDTMVKDEGLYSVSARNVAGSISCSVMLHV 1730



 Score = 48.4 bits (110), Expect = 0.001
 Identities = 66/295 (22%), Positives = 111/295 (37%), Gaps = 32/295 (10%)

Query: 202 PYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGS--- 256
           P++I     D       ++ F+      P  D  W +   G  +  G RV++   G    
Sbjct: 395 PHIIKSTLADKTVYETQTIVFEVEATSLPRADAKWFKD--GKPLRSGERVRIESSGERFR 452

Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-----PPSINLSPNSVNVESGNVAR 311
           + L  +I+ DEG Y+C   N +G     GYLTV        P    +   V+V +G    
Sbjct: 453 MELSKIIIEDEGVYTCSFSNKLGEDMTEGYLTVQTVDELRRPKFIETLQDVDVANGKSGM 512

Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSR------DKYHATAVFDGVTVLTINDTDKND 365
           F    T  P P + W  +G+   I    SR      +K  +  + +    L++    K+D
Sbjct: 513 FKAMFTADPVPDITWYFKGDE--IHSEDSRLKITVDNKPGSDKLTETTVTLSVPKCSKDD 570

Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
           +         N  G +     L +       P I     ++ T  +     +       P
Sbjct: 571 T-GEYTLKLKNKYGEAESNAFLNLL----LCPEI--QELNDVTTNVGESLAWQAIIKGNP 623

Query: 426 EPIIAWYFEGEALIQNHRRNVTNDG-----TLVLKDLDKSDSGTYTCVASSRHGK 475
           +P I W  +G+ L +  R +   D      TLV+K+++  D G Y   A +  G+
Sbjct: 624 KPDITWSKDGKVLEKGERYDFEEDKRNNKFTLVIKEVEIDDKGAYQVTAKNYLGE 678



 Score = 45.6 bits (103), Expect = 0.008
 Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)

Query: 9    GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL--PAGGL 66
            G  P+  E+P    +   +PA L C A GSP P I+WYK   ++V +T+R  +     G 
Sbjct: 2226 GHLPFFREKPQIKPIEEGKPAQLACLAVGSPKPLIQWYKND-MMVQETNRIKITEDQDGR 2284

Query: 67   FFLRATHGRVHSDAGVYWCEATNSYG 92
              L     + H D G Y   A NS G
Sbjct: 2285 SILSFNPTKEH-DVGSYKVVARNSLG 2309



 Score = 43.2 bits (97), Expect = 0.044
 Identities = 26/100 (26%), Positives = 46/100 (46%), Gaps = 3/100 (3%)

Query: 390 TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND 449
           ++++  PP II +  +++T+      VF   A   P     W+ +G+ L    R  + + 
Sbjct: 388 STEESAPPHIIKSTLADKTVYETQTIVFEVEATSLPRADAKWFKDGKPLRSGERVRIESS 447

Query: 450 GTLVLKDLDK---SDSGTYTCVASSRHGKYVWSGALLVDS 486
           G     +L K    D G YTC  S++ G+ +  G L V +
Sbjct: 448 GERFRMELSKIIIEDEGVYTCSFSNKLGEDMTEGYLTVQT 487



 Score = 41.5 bits (93), Expect = 0.14
 Identities = 28/104 (26%), Positives = 54/104 (51%), Gaps = 11/104 (10%)

Query: 110  FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV---DGGNLV 166
            FR +P+ K   +G    L CL   GSP+P + W KN   ++    +R+ +    DG +++
Sbjct: 2231 FREKPQIKPIEEGKPAQLACLAV-GSPKPLIQWYKND--MMVQETNRIKITEDQDGRSIL 2287

Query: 167  -IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
                 ++ D G Y+ +ARN+ G     +   +I ++ ++ +GP+
Sbjct: 2288 SFNPTKEHDVGSYKVVARNSLG---QTVVRTRI-VEAFVPSGPD 2327



 Score = 36.3 bits (80), Expect = 5.1
 Identities = 33/112 (29%), Positives = 45/112 (40%), Gaps = 5/112 (4%)

Query: 79   DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
            D G+Y   A+N +G AR R   L +A     F   PE +       +        G P P
Sbjct: 1613 DEGLYEAVASNEHGEARQR-VCLRIAEY-PTFIHRPE-ETIVMIRRIGQLTARVTGVPYP 1669

Query: 139  NVYWKKNGQTLLFDGDSRMHLV--DGGNLVIQDARQTDAGRYQCIARNAAGT 188
             + W K+ + L      R+     D   L+I D    D G Y   ARN AG+
Sbjct: 1670 EIKWYKDWKPLTTSSRIRIEFKEPDTSLLIISDTMVKDEGLYSVSARNVAGS 1721


>UniRef50_A2CEC7 Cluster: Novel protein similar to Down syndrome cell
            adhesion molecule; n=1; Danio rerio|Rep: Novel protein
            similar to Down syndrome cell adhesion molecule - Danio
            rerio (Zebrafish) (Brachydanio rerio)
          Length = 1904

 Score =  163 bits (397), Expect = 2e-38
 Identities = 207/841 (24%), Positives = 340/841 (40%), Gaps = 91/841 (10%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT-HRS--ILPAGG--L 66
            P I+    +  V+ ++P +L C   G+P P + W      V+ D+ HR   I+   G  L
Sbjct: 237  PKILSAFSEKVVSPNEPISLVCHVKGTPLPTVTWTLDDDPVIKDSNHRMDRIITTEGHVL 296

Query: 67   FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTV 125
             +L  +H +V SD GVY C   NS G+  S  A ++V   R    + P    +A  G   
Sbjct: 297  SYLNVSHTQV-SDGGVYRCTCNNSAGSV-SYQARINV---RGPASIRPMKNVTAIAGRDT 351

Query: 126  VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC--IAR 183
             + C    G P  ++ W K+   L F+   R    + G L + + + +D G Y C  +  
Sbjct: 352  YIHCRII-GYPYYSIKWYKDSNLLPFNHRQRA-FENNGTLKLSNVQNSDEGEYTCYVLVD 409

Query: 184  NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRRSAGGG 242
                   S   T+K+   P LI   +   A  G  V   C V    LP  + W +     
Sbjct: 410  PEKQIHRSVHVTVKV---PPLIQHSDSQSASIGQRVFIPCVVISGDLPMSITWHKDGRPI 466

Query: 243  NMPLG-RVKVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
            N  LG  +  +D   SLR+ N+     G Y+C A N   AV  S  L V  PP   + P 
Sbjct: 467  NASLGVTIDNIDFTSSLRISNLSEIHNGSYTCIARNEAAAVEHSIQLIVKVPPHFEVQPK 526

Query: 301  SVNVESGNVARFTCTATGRPEPTMFWS-VEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
              +   G      C+A G P PT+ W+  +G     F  ++ +      + +  ++L I 
Sbjct: 527  DQDGIYGKSVTLNCSAKGNPIPTIVWNHSKGAGVPQFQPIALNSGSRVQLLENGSLL-IK 585

Query: 360  DTDKNDSRNTIVCSAVNYAGSSFVRGK-LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
               + D+    +C   N  G+   +   LTV     + P +IT+ P+        M    
Sbjct: 586  HVLEEDA-GFYLCKVSNDVGADISKSMYLTV-----KIPAMITSYPNTTRAEQGHMTEMS 639

Query: 419  CTAICTPEPIIAWYFEGEALIQNHRR---NVTNDGTLVLKDLD-----KSDSGTYTCVAS 470
            CTA       + W  E   +  +  R    V   G  V+  L      + DSG ++C+A 
Sbjct: 640  CTAHGEKPIKVRWEKESHIINPDMSRYVVTVKEVGDEVISTLQILHTVREDSGFFSCIAI 699

Query: 471  SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530
            + +G+         D  I   I       V   P PP   I   V D ++ L W+     
Sbjct: 700  NSYGE---------DKGIIQLI-------VQDRPDPPEVEI-REVKDRTIALRWTMGFD- 741

Query: 531  GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590
            G+S I GY +  +  ++ S  ++         ++ +++Q    +  L P  TY   +  +
Sbjct: 742  GNSPITGYDIN-YKNKSASWASSQMTKD----VSPQLNQA--TIIELHPASTYNIRMFAK 794

Query: 591  NSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIK 650
            N  G S P   S+ +T+  D                      D   + ++   I S+ IK
Sbjct: 795  NQIGESRP---SNELTITTDEAP------------------PDGAPQDVQLEAISSQGIK 833

Query: 651  LMWEILNFYYLEGLF----IYFRPL-DNITIEYEMKTILHSNDVSGFEITSLRKYTKYEF 705
            + W+  + +   GL     + +R      + +Y    +  + D+    + +L+KYT+YE 
Sbjct: 834  VTWKPPHKHLQNGLIRSYQVCYREFGTGGSPQYNTINVDTTGDIETLTLDNLKKYTQYEV 893

Query: 706  FLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIIT 765
             +    +   G  S      TL+DVP  PP N+        T+ L WS    +  NG++ 
Sbjct: 894  RVQAANRAGMGPTSEEITITTLEDVPSRPPENVVTTATTPETISLSWSALPKEALNGMLL 953

Query: 766  GYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
            GY V+  W ++P  +     N T  +  SL +  L    +YS+Q+ A T  G G  S+++
Sbjct: 954  GYRVIF-WANLPDGELGEIRNITTTK-PSLELERLEKYTNYSIQVLAFTRAGDGVRSEQI 1011

Query: 826  Y 826
            Y
Sbjct: 1012 Y 1012



 Score =  124 bits (300), Expect = 1e-26
 Identities = 119/470 (25%), Positives = 195/470 (41%), Gaps = 38/470 (8%)

Query: 31  LNCRAGGSPSPAIRWYKGGVLVVSDT--HRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
           L C+A G P P  RW +    + SD+  H+S+    GL  + AT     SDAG Y CE  
Sbjct: 74  LPCKASGHPPPRYRWLRDNSPLESDSRYHQSV---SGLL-IEATRP---SDAGSYVCEVW 126

Query: 89  NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
           NS+G A+     +    L+    + P   + + G  V L C    GS E ++ W +N + 
Sbjct: 127 NSFGNAKVVGRLVVKQPLKAV--VSPRKVRGSVGSQVSLFC-SVTGSDEFDITWYRNAEK 183

Query: 149 LLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208
           +    + R+  ++  NLV++   ++D G YQC ARN   + +  +  +     P +++  
Sbjct: 184 IYQGINVRITGINNENLVMEGMAKSDGGAYQCFARNGKMSTQDLVQVVLEDGTPKILSAF 243

Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGGGNMPLGRVKVLDDGSLRLDNVI- 263
            + V      ++  C V G PLP V W           N  + R+   +   L   NV  
Sbjct: 244 SEKVVSPNEPISLVCHVKGTPLPTVTWTLDDDPVIKDSNHRMDRIITTEGHVLSYLNVSH 303

Query: 264 --LADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPE 321
             ++D G Y C   NS G+VS    + V  P SI    N V   +G      C   G P 
Sbjct: 304 TQVSDGGVYRCTCNNSAGSVSYQARINVRGPASIRPMKN-VTAIAGRDTYIHCRIIGYPY 362

Query: 322 PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381
            ++ W  + N   + P   R +      F+    L +++   +D         V+     
Sbjct: 363 YSIKWYKDSN---LLPFNHRQR-----AFENNGTLKLSNVQNSDEGEYTCYVLVDPEKQI 414

Query: 382 FVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGEALIQ 440
                +TV     + PP+I +  S Q+  I      PC  I    P+ I W+ +G  +  
Sbjct: 415 HRSVHVTV-----KVPPLIQHSDS-QSASIGQRVFIPCVVISGDLPMSITWHKDGRPINA 468

Query: 441 NHRRNVTN---DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
           +    + N     +L + +L +  +G+YTC+A +       S  L+V  P
Sbjct: 469 SLGVTIDNIDFTSSLRISNLSEIHNGSYTCIARNEAAAVEHSIQLIVKVP 518



 Score = 74.5 bits (175), Expect = 2e-11
 Identities = 88/350 (25%), Positives = 131/350 (37%), Gaps = 33/350 (9%)

Query: 155 SRMHLVDGGNLVIQDARQTDAGR-YQCIARN--AAGTRESAIATL----KIHIKPYLITG 207
           SR  +   G L I D +  DA   Y+C  R+     TR+S  A L     +   P ++ G
Sbjct: 1   SRYLITSTGALYILDVQSEDAVNIYRCTTRHRYTGETRQSNSARLLLSEPVDSAPVILDG 60

Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD--GSLRLDNVILA 265
            E      G  V   C+  G P P   W R     N PL            L ++    +
Sbjct: 61  FERKEVMVGHRVELPCKASGHPPPRYRWLRD----NSPLESDSRYHQSVSGLLIEATRPS 116

Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325
           D G Y CE  NS G     G L V  P    +SP  V    G+     C+ TG  E  + 
Sbjct: 117 DAGSYVCEVWNSFGNAKVVGRLVVKQPLKAVVSPRKVRGSVGSQVSLFCSVTGSDEFDIT 176

Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385
           W    N   I+ G++      T + +    L +    K+D      C A N  G    + 
Sbjct: 177 W--YRNAEKIYQGIN---VRITGINN--ENLVMEGMAKSDG-GAYQCFARN--GKMSTQD 226

Query: 386 KLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ--NHR 443
            + V  +D  P   I +  S + +         C    TP P + W  + + +I+  NHR
Sbjct: 227 LVQVVLEDGTPK--ILSAFSEKVVSPNEPISLVCHVKGTPLPTVTWTLDDDPVIKDSNHR 284

Query: 444 --RNVTNDGTLV----LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
             R +T +G ++    +     SD G Y C  ++  G   +   + V  P
Sbjct: 285 MDRIITTEGHVLSYLNVSHTQVSDGGVYRCTCNNSAGSVSYQARINVRGP 334



 Score = 56.8 bits (131), Expect = 3e-06
 Identities = 51/189 (26%), Positives = 79/189 (41%), Gaps = 9/189 (4%)

Query: 637  ELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITI-EYEMKTILHSNDVS-GFEI 694
            E +  T    +TI L W  L    L G+ + +R +    + + E+  I +        E+
Sbjct: 924  ENVVTTATTPETISLSWSALPKEALNGMLLGYRVIFWANLPDGELGEIRNITTTKPSLEL 983

Query: 695  TSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSP 754
              L KYT Y   ++ F +  +G  S     +T +DVP GPP  ++     ++ V + W P
Sbjct: 984  ERLEKYTNYSIQVLAFTRAGDGVRSEQIYTRTKEDVP-GPPAGVKAAASTSSVVFVSWLP 1042

Query: 755  PELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAET 814
            P     NGII  Y +V      P   S       V+      +TNL     YS+ + A T
Sbjct: 1043 P--HKLNGIIRKY-IVFCSNPYPTVISEFEAAPDVYFRR---LTNLNQNWQYSIWVVAVT 1096

Query: 815  IIGLGPFSQ 823
              G G  S+
Sbjct: 1097 AAGRGNTSE 1105



 Score = 47.2 bits (107), Expect = 0.003
 Identities = 33/105 (31%), Positives = 45/105 (42%), Gaps = 5/105 (4%)

Query: 374  AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF 433
            AV  AG       +TV      P  I+T      T P     V PC A+  P P I W  
Sbjct: 1094 AVTAAGRGNTSEIITVEPQAKAPARILTFS-GTVTTPWMRDIVLPCKAVGDPPPTIKWLK 1152

Query: 434  EGEA----LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
                    +  + RR+  N+G+ V++ +   DSG Y CVAS+  G
Sbjct: 1153 GNNGTPAPVSIDGRRSAHNNGSFVIRTVKAEDSGYYRCVASNNWG 1197



 Score = 45.6 bits (103), Expect = 0.008
 Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 6/95 (6%)

Query: 125  VVLECLPPRGSPEPNVYWKK--NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
            +VL C    G P P + W K  NG       D R    + G+ VI+  +  D+G Y+C+A
Sbjct: 1134 IVLPCKAV-GDPPPTIKWLKGNNGTPAPVSIDGRRSAHNNGSFVIRTVKAEDSGYYRCVA 1192

Query: 183  RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGS 217
             N  G+ E     L + ++ Y++   ED   + GS
Sbjct: 1193 SNNWGSDE---IMLNLQVQGYILQYSEDNSEEWGS 1224



 Score = 41.1 bits (92), Expect = 0.18
 Identities = 43/165 (26%), Positives = 66/165 (40%), Gaps = 23/165 (13%)

Query: 181  IARNAAGT-RESAIATLKIHIKP--YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
            +A  AAG    S I T++   K    ++T    V       +   C+  GDP P + W +
Sbjct: 1093 VAVTAAGRGNTSEIITVEPQAKAPARILTFSGTVTTPWMRDIVLPCKAVGDPPPTIKWLK 1152

Query: 238  SAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA------VSASGYLT 288
               G   P+   GR    ++GS  +  V   D G Y C A N+ G+      +   GY+ 
Sbjct: 1153 GNNGTPAPVSIDGRRSAHNNGSFVIRTVKAEDSGYYRCVASNNWGSDEIMLNLQVQGYIL 1212

Query: 289  VYDPP------SINLSPNS-----VNVESGNVARFTCTATGRPEP 322
             Y         S ++SP+       N++ G   +FT TA     P
Sbjct: 1213 QYSEDNSEEWGSYSISPSERSYRLENLKCGTWYKFTLTAQNAVGP 1257



 Score = 39.9 bits (89), Expect = 0.41
 Identities = 32/135 (23%), Positives = 55/135 (40%), Gaps = 3/135 (2%)

Query: 356 LTINDTDKNDSRNTIVCSAVN-YAGSSFVRGKLTVT-SDDDRPPPIITNGPSNQTLPIKS 413
           L I D    D+ N   C+  + Y G +       +  S+     P+I +G   + + +  
Sbjct: 11  LYILDVQSEDAVNIYRCTTRHRYTGETRQSNSARLLLSEPVDSAPVILDGFERKEVMVGH 70

Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
               PC A   P P   W  +   L  + R + +  G L+++    SD+G+Y C   +  
Sbjct: 71  RVELPCKASGHPPPRYRWLRDNSPLESDSRYHQSVSG-LLIEATRPSDAGSYVCEVWNSF 129

Query: 474 GKYVWSGALLVDSPI 488
           G     G L+V  P+
Sbjct: 130 GNAKVVGRLVVKQPL 144



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 6/76 (7%)

Query: 21   VTVARHQPATLNCRAGGSPSPAIRWYKGG---VLVVSDTHRSILPAGGLFFLRATHGRVH 77
            VT    +   L C+A G P P I+W KG       VS   R      G F +R       
Sbjct: 1126 VTTPWMRDIVLPCKAVGDPPPTIKWLKGNNGTPAPVSIDGRRSAHNNGSFVIRTVKA--- 1182

Query: 78   SDAGVYWCEATNSYGT 93
             D+G Y C A+N++G+
Sbjct: 1183 EDSGYYRCVASNNWGS 1198


>UniRef50_Q8NDA2 Cluster: Hemicentin-2; n=28; Euteleostomi|Rep:
            Hemicentin-2 - Homo sapiens (Human)
          Length = 1340

 Score =  163 bits (395), Expect = 3e-38
 Identities = 136/483 (28%), Positives = 200/483 (41%), Gaps = 31/483 (6%)

Query: 5    YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
            ++T   +P +   P  V     +   L C A G P P I W K G+ V +     +LP G
Sbjct: 838  FLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGG 897

Query: 65   GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
             L   R  H     DAG Y C A NS G+A  +  T  V  +            + +G  
Sbjct: 898  QL---RIAHASPE-DAGNYLCIAKNSAGSAMGK--TRLVVQVPPVIENGLPDLSTTEGSH 951

Query: 125  VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
              L C   RGSPEPN+ W K+GQ +    + +  +   G L++++    DAG Y C A N
Sbjct: 952  AFLPC-KARGSPEPNITWDKDGQPVS-GAEGKFTIQPSGELLVKNLEGQDAGTYTCTAEN 1009

Query: 185  AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
            A G     +  L I + P   T P D   + G  +  +C   G P P + W  +    + 
Sbjct: 1010 AVGRARRRVH-LTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVN----DR 1064

Query: 245  PLGRVKVLDDGSLRLDNVILA--DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
            P+       DG   L    ++  D G Y C AEN VG   A  ++ V + P +     S 
Sbjct: 1065 PVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGEAFSY 1124

Query: 303  NVES-GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
             VE  G   +  C   G P P + W  +G      P   R  +    + +G   LTI+ T
Sbjct: 1125 LVEPVGGSIQLDCVVRGDPVPDIHWIKDG-----LP--LRGSHLRHQLQNGS--LTIHRT 1175

Query: 362  DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
            +++D+     C A N  G   V  K+ +      P  +    P + T+         C A
Sbjct: 1176 ERDDA-GRYQCLAENEMG---VAKKVVILVLQSAP--VFQVEPQDMTVRSGDDVALRCQA 1229

Query: 422  ICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
               P P I W   G+ L  + R     DG+L L++++  D+GTY CVA +  G       
Sbjct: 1230 TGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARAF 1289

Query: 482  LLV 484
            L+V
Sbjct: 1290 LVV 1292



 Score =  162 bits (394), Expect = 5e-38
 Identities = 130/470 (27%), Positives = 196/470 (41%), Gaps = 26/470 (5%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAG 64
            VT    P I +   D TV    P  L C + G P+P + W K G  L    +   + P+G
Sbjct: 748  VTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSG 807

Query: 65   GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
             L   +A    +H  AG Y C A NS G A  ++  L V        L P   ++   + 
Sbjct: 808  ALEIGQALP--IH--AGRYTCSARNSAGVAH-KHVFLTVQASPVVKPL-PSVVRAVAEEE 861

Query: 125  VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
            V+L C    G P P + W+K G  +     +++  + GG L I  A   DAG Y CIA+N
Sbjct: 862  VLLPC-EASGIPRPTITWQKEGLNVATGVSTQV--LPGGQLRIAHASPEDAGNYLCIAKN 918

Query: 185  AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
            +AG+       L + + P +  G  D+    GS     C+  G P P++ W +     + 
Sbjct: 919  SAGSAMGK-TRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSG 977

Query: 245  PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
              G+  +   G L + N+   D G Y+C AEN+VG      +LT+   P     P   ++
Sbjct: 978  AEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSL 1037

Query: 305  ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
              G+     C A G P P + W+V  N   +  G+S          DG + L      + 
Sbjct: 1038 RLGDRLWLRCAARGSPTPRIGWTV--NDRPVTEGVSEQ--------DGGSTLQRAAVSRE 1087

Query: 365  DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
            DS  T VC A N  G +     + V       P +     S    P+       C     
Sbjct: 1088 DS-GTYVCWAENRVGRTQAVSFVHV----KEAPVLQGEAFSYLVEPVGGSIQLDCVVRGD 1142

Query: 425  PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
            P P I W  +G  L  +H R+   +G+L +   ++ D+G Y C+A +  G
Sbjct: 1143 PVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMG 1192



 Score =  140 bits (340), Expect = 2e-31
 Identities = 130/452 (28%), Positives = 183/452 (40%), Gaps = 32/452 (7%)

Query: 29   ATLNCRAGGSPSPAIRWYKGGVLV---VSDTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85
            A L C A GSP P + W+K G  +   +      +LP+  L  L    G    D+  + C
Sbjct: 678  ALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNAL--LLTAPG--PQDSAQFEC 733

Query: 86   EATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK 144
              +N  G A R    T+HV     + + +      A    VVL C    G P P V W K
Sbjct: 734  VVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMA---PVVLTC-HSTGIPAPTVSWSK 789

Query: 145  NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL 204
             G  L   G S   +   G L I  A    AGRY C ARN+AG     +  L +   P +
Sbjct: 790  AGAQLGARG-SGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHV-FLTVQASPVV 847

Query: 205  ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNVI 263
               P  V A     V   C   G P P + W++   G N+  G   +VL  G LR+ +  
Sbjct: 848  KPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKE--GLNVATGVSTQVLPGGQLRIAHAS 905

Query: 264  LADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPT 323
              D G Y C A+NS G+      L V  PP I      ++   G+ A   C A G PEP 
Sbjct: 906  PEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPN 965

Query: 324  MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383
            + W  +G        +S  +   T    G   L + + +  D+  T  C+A N  G +  
Sbjct: 966  ITWDKDGQ------PVSGAEGKFTIQPSG--ELLVKNLEGQDA-GTYTCTAENAVGRARR 1016

Query: 384  RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR 443
            R  LT+        P+ T  P +++L +       C A  +P P I W      + +   
Sbjct: 1017 RVHLTIL-----VLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVS 1071

Query: 444  RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
                   TL    + + DSGTY C A +R G+
Sbjct: 1072 EQ-DGGSTLQRAAVSREDSGTYVCWAENRVGR 1102



 Score =  131 bits (316), Expect = 1e-28
 Identities = 136/492 (27%), Positives = 209/492 (42%), Gaps = 36/492 (7%)

Query: 10  EAPYIIEQPLDVTVAR--HQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
           + P   E P   TV++    P  L C   G P+P + W K  + V S     ++  GG  
Sbjct: 34  QVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRL 93

Query: 68  FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
            L        + AG Y C A N+   AR       +   R             +G  V L
Sbjct: 94  QLSRLQP---AQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRL 150

Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFD-GDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
           +C    G P P+V W K+G  L  D G      +DGG+LV++    +DAG Y C+A N A
Sbjct: 151 DC-EADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLWASDAGAYTCVAHNPA 209

Query: 187 GTRESAIATLKIHIKPYLITGPE---DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
           G  ++ + T+ + + P +  G +    +V++ G  VT  C V G P   V W +   G  
Sbjct: 210 G-EDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKD--GLP 266

Query: 244 MPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
           +PL +  +L     +LR+  V LAD G ++C A +  G   A    T+  P  ++ S  S
Sbjct: 267 LPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGV--ADRNFTLQCP--LSWSRWS 322

Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
             +           +  RP      S  G +         +   + ++  G + L +   
Sbjct: 323 SRMTWWWFVAPWWNSRARPGAFPCLSCRGMK-------DGEPLLSQSLEQGPS-LQLEAV 374

Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG-PSNQTLPIKSMAVFPCT 420
              DS  T  C AV+ AG +    +LTV      PP I  +G P+  +L   +     C 
Sbjct: 375 GAGDS-GTYSCVAVSEAGEARRHFQLTVM----EPPHIEDSGQPTELSLTPGAPMELLCD 429

Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
           A  TP+P I W+ +G+AL +    N      L ++++   D+G YTC+A S  G    S 
Sbjct: 430 AQGTPQPNITWHKDGQALTR-LENNSRATRVLRVENVQVRDAGLYTCLAESPAGAIEKSF 488

Query: 481 ALLVDSPINPNI 492
            + V +P  PNI
Sbjct: 489 RVRVQAP--PNI 498



 Score =  122 bits (294), Expect = 6e-26
 Identities = 123/475 (25%), Positives = 190/475 (40%), Gaps = 48/475 (10%)

Query: 6   VTSGEAPYIIE--QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
           +T  E P+I +  QP ++++    P  L C A G+P P I W+K G  +    + S    
Sbjct: 399 LTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATR 458

Query: 64  GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG- 122
                LR  + +V  DAG+Y C A +  G       +  V V      + P   +   G 
Sbjct: 459 ----VLRVENVQVR-DAGLYTCLAESPAGAIEK---SFRVRVQAPPNIVGPRGPRFVVGL 510

Query: 123 --DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
               +VLEC      P P + W ++G  L  D  ++     G  L +Q     D+G Y C
Sbjct: 511 APGQLVLEC-SVEAEPAPKITWHRDGIVLQEDAHTQFP-ERGRFLQLQALSTADSGDYSC 568

Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
            ARNAAG+   A   ++IH  P + +GP  V      +    C+  G P P V WR+   
Sbjct: 569 TARNAAGSTSVAFR-VEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRV 627

Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
             +    R ++L +GSLR+  V+  D G Y C A NS G+      L V           
Sbjct: 628 PLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRV----------- 676

Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
                   +A   C A+G P+P + W  +G +      + +  Y           L +  
Sbjct: 677 --------LALLPCEASGSPKPLVVWWKDGQKLDF--RLQQGAYRLLP----SNALLLTA 722

Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
               DS     C   N  G +    ++TV       PP I +  ++ T+ + +  V  C 
Sbjct: 723 PGPQDSAQ-FECVVSNEVGEAHRLYQVTV-----HVPPTIADDQTDFTVTMMAPVVLTCH 776

Query: 421 AICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
           +   P P ++W   G  L  +     V+  G L +       +G YTC A +  G
Sbjct: 777 STGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAG 831



 Score =  119 bits (287), Expect = 4e-25
 Identities = 118/460 (25%), Positives = 175/460 (38%), Gaps = 45/460 (9%)

Query: 31  LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
           L C     P+P I W++ G+++  D H      G    L+A      +D+G Y C A N+
Sbjct: 517 LECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALST---ADSGDYSCTARNA 573

Query: 91  YG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
            G T+ +    +H        R  P +   +   T +L C    G P P V W+K+ +  
Sbjct: 574 AGSTSVAFRVEIHTV---PTIRSGPPAVNVSVNQTALLPCQAD-GVPAPLVSWRKD-RVP 628

Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
           L     R  ++  G+L IQ     DAG Y C+A N+AG+         + + P       
Sbjct: 629 LDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLALLP------- 681

Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL--GRVKVLDDGSLRLDNVILADE 267
                        C   G P P V+W +     +  L  G  ++L   +L L      D 
Sbjct: 682 -------------CEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDS 728

Query: 268 GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327
            ++ C   N VG       +TV+ PP+I        V        TC +TG P PT+ WS
Sbjct: 729 AQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWS 788

Query: 328 VEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387
             G +     G     Y  +    G   +       +  R T  CSA N AG +     L
Sbjct: 789 KAGAQL----GARGSGYRVSP--SGALEIG-QALPIHAGRYT--CSARNSAGVAHKHVFL 839

Query: 388 TVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT 447
           TV +      P++   PS      +   + PC A   P P I W  EG  +       V 
Sbjct: 840 TVQAS-----PVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVL 894

Query: 448 NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
             G L +      D+G Y C+A +  G  +    L+V  P
Sbjct: 895 PGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVP 934



 Score =  110 bits (264), Expect = 3e-22
 Identities = 73/252 (28%), Positives = 115/252 (45%), Gaps = 11/252 (4%)

Query: 79  DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
           D+G Y C A +  G AR       +     E   +P       G  + L C   +G+P+P
Sbjct: 378 DSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLC-DAQGTPQP 436

Query: 139 NVYWKKNGQTLL-FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
           N+ W K+GQ L   + +SR   V    L +++ +  DAG Y C+A + AG  E +   ++
Sbjct: 437 NITWHKDGQALTRLENNSRATRV----LRVENVQVRDAGLYTCLAESPAGAIEKSFR-VR 491

Query: 198 IHIKPYLI--TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
           +   P ++   GP  VV      +  +C V  +P P + W R  G         +  + G
Sbjct: 492 VQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRD-GIVLQEDAHTQFPERG 550

Query: 256 S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
             L+L  +  AD G+YSC A N+ G+ S +  + ++  P+I   P +VNV     A   C
Sbjct: 551 RFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPC 610

Query: 315 TATGRPEPTMFW 326
            A G P P + W
Sbjct: 611 QADGVPAPLVSW 622



 Score =  102 bits (244), Expect = 7e-20
 Identities = 114/460 (24%), Positives = 200/460 (43%), Gaps = 53/460 (11%)

Query: 30  TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
           T+ C   GSP   + W K G L +  + R++L   G   LR +  ++ +DAG++ C A +
Sbjct: 245 TMVCPVRGSPPIHVSWLKDG-LPLPLSQRTLLHGSG-HTLRISKVQL-ADAGIFTCVAAS 301

Query: 90  SYGTARSRNATLHVAVL--REEFRLE----PESKQSAQGDTVVLECLPPRGSPEPNVYWK 143
             G A  RN TL   +   R   R+          +++       CL  RG         
Sbjct: 302 PAGVA-DRNFTLQCPLSWSRWSSRMTWWWFVAPWWNSRARPGAFPCLSCRGM-------- 352

Query: 144 KNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY 203
           K+G+ LL        L  G +L ++     D+G Y C+A + AG        L +   P+
Sbjct: 353 KDGEPLLSQS-----LEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQ-LTVMEPPH 406

Query: 204 LITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS--LRL 259
           +     P ++    G+ +   C   G P P++ W +        L R++     +  LR+
Sbjct: 407 IEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDG----QALTRLENNSRATRVLRV 462

Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS----VNVESGNVARFTCT 315
           +NV + D G Y+C AE+  GA+  S  + V  PP+I + P      V +  G +    C+
Sbjct: 463 ENVQVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNI-VGPRGPRFVVGLAPGQLV-LECS 520

Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
               P P + W  +G   I+    +  ++     F  + +  ++  D  D      C+A 
Sbjct: 521 VEAEPAPKITWHRDG---IVLQEDAHTQFPERGRF--LQLQALSTADSGDYS----CTAR 571

Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG 435
           N AGS+ V  ++ + +      P I +GP    + +   A+ PC A   P P+++W  + 
Sbjct: 572 NAAGSTSVAFRVEIHT-----VPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDR 626

Query: 436 EAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
             L  ++ R  +  +G+L ++ +   D+G Y C+AS+  G
Sbjct: 627 VPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAG 666



 Score = 85.0 bits (201), Expect = 1e-14
 Identities = 84/316 (26%), Positives = 123/316 (38%), Gaps = 18/316 (5%)

Query: 165 LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT-GSSVTFQC 223
           L IQ+A+ +D G Y C   N AG       TL + + P       + V+Q  GS +   C
Sbjct: 1   LEIQEAQVSDKGLYSCKVSNVAGEAVRTF-TLTVQVPPTFENPKTETVSQVAGSPLVLTC 59

Query: 224 RVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSA 283
            V G P P V W +             V   G L+L  +  A  G Y+C AEN+      
Sbjct: 60  DVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARK 119

Query: 284 SGYLTVYDPPSINLS--PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341
              + V   P I  S      +V  G   R  C A G+P P + W  +G+      G   
Sbjct: 120 DFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPL----GQDM 175

Query: 342 DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401
              H     DG + L +     +D+     C A N AG       + V      PP I  
Sbjct: 176 GP-HLRFYLDGGS-LVLKGLWASDA-GAYTCVAHNPAGEDARLHTVNVLV----PPTIKQ 228

Query: 402 NGPSNQTLPIK--SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLD 458
               + TL  +   +    C    +P   ++W  +G  L  + R  +   G TL +  + 
Sbjct: 229 GADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQ 288

Query: 459 KSDSGTYTCVASSRHG 474
            +D+G +TCVA+S  G
Sbjct: 289 LADAGIFTCVAASPAG 304



 Score = 84.2 bits (199), Expect = 2e-14
 Identities = 74/263 (28%), Positives = 106/263 (40%), Gaps = 17/263 (6%)

Query: 78  SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
           SD G+Y C+ +N  G A  R  TL V V       + E+     G  +VL C    G P 
Sbjct: 9   SDKGLYSCKVSNVAGEA-VRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTC-DVSGVPA 66

Query: 138 PNVYWKKNGQTLLFDGDSRMHLV--DGGNLVIQDARQTDAGRYQCIARN--AAGTRESAI 193
           P V W K+   +     S +H V   GG L +   +   AG Y C+A N  A   ++  +
Sbjct: 67  PTVTWLKDRMPV---ESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVV 123

Query: 194 ATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKV 251
           A L    I+   +     V+   G  V   C   G P PDV W +        +G  ++ 
Sbjct: 124 AVLVAPRIRSSGVAREHHVLE--GQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRF 181

Query: 252 -LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV---ESG 307
            LD GSL L  +  +D G Y+C A N  G  +    + V  PP+I    +         G
Sbjct: 182 YLDGGSLVLKGLWASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPG 241

Query: 308 NVARFTCTATGRPEPTMFWSVEG 330
            +    C   G P   + W  +G
Sbjct: 242 ELVTMVCPVRGSPPIHVSWLKDG 264



 Score = 41.1 bits (92), Expect = 0.18
 Identities = 34/141 (24%), Positives = 60/141 (42%), Gaps = 6/141 (4%)

Query: 403 GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL---IQNHRRNVTNDGTLVLKDLDK 459
           G   Q   ++ +A+ PC A  +P+P++ W+ +G+ L   +Q     +     L+L     
Sbjct: 666 GSDRQGRDLRVLALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGP 725

Query: 460 SDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTS 519
            DS  + CV S+  G+      + V  P  P I   +  D +     P     H+    +
Sbjct: 726 QDSAQFECVVSNEVGEAHRLYQVTVHVP--PTIADDQ-TDFTVTMMAPVVLTCHSTGIPA 782

Query: 520 VTLSWSQNNKIGSSSILGYQV 540
            T+SWS+      +   GY+V
Sbjct: 783 PTVSWSKAGAQLGARGSGYRV 803


>UniRef50_Q5XNV8 Cluster: Neogenin/DCC long isoform; n=5;
           Vertebrata|Rep: Neogenin/DCC long isoform - Petromyzon
           marinus (Sea lamprey)
          Length = 1415

 Score =  162 bits (394), Expect = 5e-38
 Identities = 192/732 (26%), Positives = 298/732 (40%), Gaps = 89/732 (12%)

Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVI-- 167
           F LEP       G  VVL C      P      +K+G  L    D R HL+  G+L+I  
Sbjct: 47  FTLEPAGTVVVAGSPVVLSCTVDSDKPI-KFGTRKDGVLLDTVADERRHLLANGSLLIRT 105

Query: 168 ---QDARQTDAGRYQC-IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223
              ++  + D+GRYQC +  +  G+  S  A + +  +P  ++     +   G SV   C
Sbjct: 106 GGHEELARIDSGRYQCEVTVHGLGSIISRPAAVTLIGEPRFVSSSLSTLVIQGDSVVLDC 165

Query: 224 RVGGDPL-PDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEA-------E 275
                 L  +V W +  G       +V VL  G L L N   AD G+Y C+         
Sbjct: 166 GAEVTGLWNEVRWFKE-GRSITEDSQVMVLSSGDLLLQNASKADGGKYFCQLVFGGRTFT 224

Query: 276 NSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII 335
           N    +S    +    P  +   P  V+V  G+ A   C   G P P++ W+  G  +++
Sbjct: 225 NQGTNLSVLPEMESNRPCVVLRHPVDVSVRLGHTATLECVVAGFPAPSVHWT-RGTESVL 283

Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN-TIVCSAVNYAGSSFVRGKLTVTSDDD 394
               S        V  G+  L I++  ++D+ + T +  A N     +   KLTV     
Sbjct: 284 SERFS-------VVAGGI--LRIDNVQQDDAGDYTCIIKAQNETQRLYA--KLTVLE--- 329

Query: 395 RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVL 454
             PP I +GP N+   +    +  C A   P P+I+W+  G+ +I +    +  DG+L +
Sbjct: 330 --PPRILHGPENRNASVSDDIILECQAEGRPRPVISWFQNGDLIIPDDFIQIV-DGSLHI 386

Query: 455 KDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHN 514
             +  SD G Y C+A S       +  L+V +   P I          L   P + +T  
Sbjct: 387 LGVMASDEGVYQCMAESEVDGMQAAAQLVVINHAVPGI----------LASSPPRGMTAV 436

Query: 515 VTDTS-VTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYV 573
           +  T  + LSW    +    S+L Y V  + R       + R  R   V   +V +   V
Sbjct: 437 LVSTRFIRLSWRAPAE-SRGSVLHYSV-YYVRV-----GSVRERR---VDTLQVSELQLV 486

Query: 574 VKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTD 633
           V  L P   Y F V   N    +GP         G+ S  L   T      +    +L  
Sbjct: 487 VGELRPETGYSFQVVAVNQ---AGP---------GERSAPLRITT--QPEVQVPGPVLNL 532

Query: 634 HIVELIEATPIDSKTIKLMWE--ILNFYYLEGLFIYFRPLD-NITIEYEMKTILHSNDVS 690
           H+V       I + ++ L W+     F  +    +Y+  LD   T E++  T     D  
Sbjct: 533 HVV------AISTTSVSLQWDPPANVFSPIMHYKLYYMQLDGEATTEHDQDT-----DGP 581

Query: 691 GFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHL 750
            F    LRK+T+Y F ++ + K   G  S   + +T  DVP G P  + + ++N+ +V +
Sbjct: 582 SFTKEGLRKFTRYSFRVVAYNKHGPGVSSEDTIVRTYSDVPSGSPQELILEVVNSQSVLV 641

Query: 751 KWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQI 810
           +W PP L+  NG ITGY            ++   I  T H   S +   L  G  YS ++
Sbjct: 642 RWKPPLLETHNGDITGYK---RHEGKAGRRAEAEIEETAH--LSYLAVGLDRGSEYSFRV 696

Query: 811 AAETIIGLGPFS 822
           AA    G GPFS
Sbjct: 697 AAVNSNGTGPFS 708



 Score =  109 bits (263), Expect = 3e-22
 Identities = 80/284 (28%), Positives = 130/284 (45%), Gaps = 17/284 (5%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPS-PAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
           P  +   L   V +     L+C A  +     +RW+K G  +  D+   +L +G L    
Sbjct: 144 PRFVSSSLSTLVIQGDSVVLDCGAEVTGLWNEVRWFKEGRSITEDSQVMVLSSGDLLLQN 203

Query: 71  ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR-----LEPESKQSAQGDTV 125
           A+     +D G Y+C+      T  ++   L V    E  R       P       G T 
Sbjct: 204 ASK----ADGGKYFCQLVFGGRTFTNQGTNLSVLPEMESNRPCVVLRHPVDVSVRLGHTA 259

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
            LEC+   G P P+V+W +  +++L +   R  +V GG L I + +Q DAG Y CI + A
Sbjct: 260 TLECVVA-GFPAPSVHWTRGTESVLSE---RFSVVAGGILRIDNVQQDDAGDYTCIIK-A 314

Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
               +   A L +   P ++ GPE+  A     +  +C+  G P P + W ++ G   +P
Sbjct: 315 QNETQRLYAKLTVLEPPRILHGPENRNASVSDDIILECQAEGRPRPVISWFQN-GDLIIP 373

Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
              ++++D GSL +  V+ +DEG Y C AE+ V  + A+  L V
Sbjct: 374 DDFIQIVD-GSLHILGVMASDEGVYQCMAESEVDGMQAAAQLVV 416



 Score = 77.0 bits (181), Expect = 3e-12
 Identities = 59/194 (30%), Positives = 95/194 (48%), Gaps = 14/194 (7%)

Query: 14  IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
           ++  P+DV+V     ATL C   G P+P++ W +G   V+S+  R  + AGG+  LR  +
Sbjct: 244 VLRHPVDVSVRLGHTATLECVVAGFPAPSVHWTRGTESVLSE--RFSVVAGGI--LRIDN 299

Query: 74  GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPP 132
            +   DAG Y C       T R       + VL     L  PE++ ++  D ++LEC   
Sbjct: 300 VQ-QDDAGDYTCIIKAQNETQR---LYAKLTVLEPPRILHGPENRNASVSDDIILEC-QA 354

Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
            G P P + W +NG  ++   D  + +VD G+L I     +D G YQC+A +     ++A
Sbjct: 355 EGRPRPVISWFQNGDLII--PDDFIQIVD-GSLHILGVMASDEGVYQCMAESEVDGMQAA 411

Query: 193 IATLKI-HIKPYLI 205
              + I H  P ++
Sbjct: 412 AQLVVINHAVPGIL 425



 Score = 46.4 bits (105), Expect = 0.005
 Identities = 63/225 (28%), Positives = 96/225 (42%), Gaps = 20/225 (8%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
           E P I+  P +   +      L C+A G P P I W++ G L++ D    I+  G L  L
Sbjct: 329 EPPRILHGPENRNASVSDDIILECQAEGRPRPVISWFQNGDLIIPDDFIQIVD-GSLHIL 387

Query: 70  RATHGRVHSDAGVYWCEATNSYG--TARSRNATLHVAVLREEFRLEPESKQSAQGDT--V 125
               G + SD GVY C A +      A ++   ++ AV        P    +    T  +
Sbjct: 388 ----GVMASDEGVYQCMAESEVDGMQAAAQLVVINHAVPGILASSPPRGMTAVLVSTRFI 443

Query: 126 VLECLPP---RGSP-EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
            L    P   RGS    +VY+ + G       D+    V    LV+ + R      +Q +
Sbjct: 444 RLSWRAPAESRGSVLHYSVYYVRVGSVRERRVDTLQ--VSELQLVVGELRPETGYSFQVV 501

Query: 182 ARNAAGTRESAIATLKIHIKPYL-ITGPE---DVVAQTGSSVTFQ 222
           A N AG  E + A L+I  +P + + GP     VVA + +SV+ Q
Sbjct: 502 AVNQAGPGERS-APLRITTQPEVQVPGPVLNLHVVAISTTSVSLQ 545



 Score = 44.0 bits (99), Expect = 0.025
 Identities = 66/285 (23%), Positives = 107/285 (37%), Gaps = 26/285 (9%)

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPLGRVKVLDDGSLRL 259
           P     P   V   GS V   C V  D  P     R  G     +   R  +L +GSL +
Sbjct: 45  PRFTLEPAGTVVVAGSPVVLSCTVDSDK-PIKFGTRKDGVLLDTVADERRHLLANGSLLI 103

Query: 260 -----DNVILADEGEYSCEAE-NSVGAV-SASGYLTVYDPPSINLSPNSVNVESGNVARF 312
                + +   D G Y CE   + +G++ S    +T+   P    S  S  V  G+    
Sbjct: 104 RTGGHEELARIDSGRYQCEVTVHGLGSIISRPAAVTLIGEPRFVSSSLSTLVIQGDSVVL 163

Query: 313 TCTATGRPEPTMFWSVEGNRTIIFP-GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371
            C A    E T  W    N    F  G S  +     V     +L + +  K D      
Sbjct: 164 DCGA----EVTGLW----NEVRWFKEGRSITEDSQVMVLSSGDLL-LQNASKADG-GKYF 213

Query: 372 CSAVNYAGSSFVRG--KLTVTSD-DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428
           C  V + G +F      L+V  + +   P ++   P + ++ +   A   C     P P 
Sbjct: 214 CQLV-FGGRTFTNQGTNLSVLPEMESNRPCVVLRHPVDVSVRLGHTATLECVVAGFPAPS 272

Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
           + W   G   + + R +V   G L + ++ + D+G YTC+  +++
Sbjct: 273 VHWT-RGTESVLSERFSVVAGGILRIDNVQQDDAGDYTCIIKAQN 316


>UniRef50_Q4RYE5 Cluster: Chromosome 2 SCAF14976, whole genome
           shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 2
           SCAF14976, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 2095

 Score =  162 bits (394), Expect = 5e-38
 Identities = 195/772 (25%), Positives = 317/772 (41%), Gaps = 78/772 (10%)

Query: 76  VHSDAGVYWCEATNSYGTARSRNATLHVAV---------LREEFRLEPESKQSAQGDT-V 125
           V  DAG Y+ +A N        +  + ++V         +     + P +     G + V
Sbjct: 14  VAPDAGRYYVQAVNDKNGDNKTSQPITLSVENVGGPADPIAPTIIIPPRNTSVVTGTSEV 73

Query: 126 VLECLP-PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC--IA 182
            +EC+   R   + ++ W+KNG  L+  G S         L I     +DAG Y+C  I 
Sbjct: 74  TMECVANARPLIKLSIVWRKNG-VLVSGGLSDF----SRRLTIFGPALSDAGYYECEAIL 128

Query: 183 RNAAGTRESAIATLKIHIKPYLITGPED-VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
           R+++    SA A L ++  P  I  PE  + A+    V   C+  G P PD++W + A  
Sbjct: 129 RSSSVPSVSAGAYLHVYEPPQFIKEPEKHITAEMEKVVDIPCQARGTPQPDIVWYKDALP 188

Query: 242 GN-MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLSP 299
            + + + R +VL  GSL+++ ++  D G + C A N  G V  + YL V    P+I   P
Sbjct: 189 IDPVKMLRYRVLVGGSLQVNGLLPDDTGMFQCFARNVAGEVQTNTYLAVTSIAPNITAGP 248

Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
           +   V  G      C  +G P P + W  +G R +    +   ++  T +  G   L I+
Sbjct: 249 SDSTVIDGMSIILHCETSGAPRPAITWQ-KGERVLASGSVQLPRF--TLLESGS--LLIS 303

Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419
            +  +D+  T  C A N  G       L V +        IT  P +Q++   + A   C
Sbjct: 304 PSHISDA-GTYTCMASNSRGIDEAAADLVVWARTR-----ITTPPQDQSVIKGTKAFMTC 357

Query: 420 TAICTPEPIIA--WYFEGEAL-IQNHRRNVTN-DGTLVLKDLDKSDSGTYTCVASSRHGK 475
                P   +   W  EG A+ +Q   R  T+ DGTL +      D GTYTC  +S  G 
Sbjct: 358 GVTHDPSVTVKHIWEKEGTAINVQAIPRMRTDPDGTLHISQTWSGDIGTYTCRVTSVGGN 417

Query: 476 YVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKP--ITHNVTDTSVTLSWSQNNKIGSS 533
              S  L V  P+ P            LP PP  P  +       ++ L+W++    G+S
Sbjct: 418 DSRSAHLRVSCPVPPYPR-------RQLPHPPENPTAVLSTSEKRAINLAWAKPFD-GNS 469

Query: 534 SILGYQVEVFSRETLSGNNTPRNSRGWVVIARRV--HQTHYVVKSLIPGITYMFIVRTEN 591
            ++ Y +EV      S NN P     W ++   +    T   V  LIP  +Y F +   N
Sbjct: 470 PLIRYILEV------SENNAP-----WAILLASIEPESTEVTVNGLIPARSYQFRLCAVN 518

Query: 592 SHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKL 651
             G    S  +D V++ ++  S      +++         T+  + +    P +S    +
Sbjct: 519 DVGKGQFSKETDRVSLPEEPPSAPPQNVIASGR-------TNQSIMIQWQPPPESHQNGI 571

Query: 652 MWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFY 711
                    L G  + +R L  + ++Y++K I  S DV+   +  L  +T YE  +  F 
Sbjct: 572 ---------LRGYVVRYR-LTGLPVDYQLKNI-SSPDVTNLLLEDLIIWTNYEIEVAAFN 620

Query: 712 KKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVV 771
               G  S+     TL  VP   P N++   +N+TT+   W+ P  Q  NGI  GY ++ 
Sbjct: 621 GAGLGAFSHKVTEWTLQGVPTIAPGNVQAEAVNSTTIRFTWTAPNPQFINGINQGYKLLT 680

Query: 772 NWLDVPANKSMVAINTTVHQATSL-IMTNLTSGVSYSVQIAAETIIGLGPFS 822
                  + +MV +      +  +  +T L     Y   +   T  G GP S
Sbjct: 681 WEPRKDKDVTMVIVRPNFQDSVHVGYVTGLKKFTEYYTSVLCFTTPGDGPRS 732



 Score =  135 bits (327), Expect = 6e-30
 Identities = 105/332 (31%), Positives = 147/332 (44%), Gaps = 22/332 (6%)

Query: 11  APYIIEQPLDVTVARH-QPATLNCRAGGSP--SPAIRWYKGGVLVVSDTHRSILPAGGL- 66
           AP II  P + +V       T+ C A   P    +I W K GVLV          +GGL 
Sbjct: 54  APTIIIPPRNTSVVTGTSEVTMECVANARPLIKLSIVWRKNGVLV----------SGGLS 103

Query: 67  -FFLRAT-HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGD 123
            F  R T  G   SDAG Y CEA     +  S +A  ++ V    +F  EPE   +A+ +
Sbjct: 104 DFSRRLTIFGPALSDAGYYECEAILRSSSVPSVSAGAYLHVYEPPQFIKEPEKHITAEME 163

Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
            VV      RG+P+P++ W K+   +      R  ++ GG+L +      D G +QC AR
Sbjct: 164 KVVDIPCQARGTPQPDIVWYKDALPIDPVKMLRYRVLVGGSLQVNGLLPDDTGMFQCFAR 223

Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR---RSAG 240
           N AG  ++        I P +  GP D     G S+   C   G P P + W+   R   
Sbjct: 224 NVAGEVQTNTYLAVTSIAPNITAGPSDSTVIDGMSIILHCETSGAPRPAITWQKGERVLA 283

Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
            G++ L R  +L+ GSL +    ++D G Y+C A NS G   A+  L V+    I   P 
Sbjct: 284 SGSVQLPRFTLLESGSLLISPSHISDAGTYTCMASNSRGIDEAAADLVVWARTRITTPPQ 343

Query: 301 SVNVESGNVARFTCTATGRPEPTM--FWSVEG 330
             +V  G  A  TC  T  P  T+   W  EG
Sbjct: 344 DQSVIKGTKAFMTCGVTHDPSVTVKHIWEKEG 375



 Score = 68.1 bits (159), Expect = 1e-09
 Identities = 47/149 (31%), Positives = 73/149 (48%), Gaps = 8/149 (5%)

Query: 687  NDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQ-TLDDVPDGPPINIEMFILNT 745
            N     ++T L KY  YE  ++ F +  +G+PS   + + TLDDVP GPP+ I    + T
Sbjct: 1135 NATHSVQLTGLGKYVLYEIQVLAFTRMGDGRPSAPPILERTLDDVP-GPPVGILFPEVRT 1193

Query: 746  TTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMV-AINTTVHQATSLIMTNLTSGV 804
            T+V L W  P     NGII  Y +  +     +N + V  +N +  Q T   +TNL    
Sbjct: 1194 TSVRLIWQSP--SEPNGIILAYQITYHHNSTNSNTATVDVLNPSARQYT---VTNLKPES 1248

Query: 805  SYSVQIAAETIIGLGPFSQKVYFNIDSRS 833
             Y  +I A+T  G G  ++ +    + R+
Sbjct: 1249 VYVFRITAQTRKGWGEAAEALVVTTEKRA 1277



 Score = 59.3 bits (137), Expect = 6e-07
 Identities = 37/152 (24%), Positives = 67/152 (44%), Gaps = 3/152 (1%)

Query: 673  NITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPD 732
            +++  Y ++ +  S+ +  +E+  L K+ +YE  +  +    EG  S  +     + VP 
Sbjct: 1471 DLSAPYSIRNLTDSSLIQ-YELDKLSKHKRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPT 1529

Query: 733  GPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQA 792
             PP N+ +     T + + W PP +  QNG I GY V   W +         + T     
Sbjct: 1530 APPQNVAIQSATATQLDVTWDPPPVDAQNGDIQGYKVYF-W-EFQRKNETERLRTLFMPE 1587

Query: 793  TSLIMTNLTSGVSYSVQIAAETIIGLGPFSQK 824
              + + NLT   +Y + +A     G GP S++
Sbjct: 1588 GGVKLKNLTGYTTYMISVAPFNAAGDGPRSRR 1619



 Score = 56.0 bits (129), Expect = 6e-06
 Identities = 44/190 (23%), Positives = 90/190 (47%), Gaps = 13/190 (6%)

Query: 639 IEATPIDSKTIKLMWEILNFYYLEGL-----FIYFRPLDNITIEYEMKTILHSNDVSGFE 693
           ++A  ++S TI+  W   N  ++ G+      + + P  +  +   +      + V    
Sbjct: 647 VQAEAVNSTTIRFTWTAPNPQFINGINQGYKLLTWEPRKDKDVTMVIVRPNFQDSVHVGY 706

Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
           +T L+K+T+Y   ++ F    +G  S  R A+T +D P G   ++    +  T++ + WS
Sbjct: 707 VTGLKKFTEYYTSVLCFTTPGDGPRSPPRAARTHEDTP-GAVGHLSFTEILDTSLKVSWS 765

Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT-SLIMTNLTSGVSYSVQIAA 812
            P    +NG++TGY   ++W +   N++   +   +   T    +T LT+  +Y++++A 
Sbjct: 766 EP--SEKNGVLTGYR--ISWEEY--NRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAG 819

Query: 813 ETIIGLGPFS 822
            T  G G  S
Sbjct: 820 MTSKGQGLLS 829



 Score = 55.2 bits (127), Expect = 1e-05
 Identities = 29/98 (29%), Positives = 50/98 (51%), Gaps = 2/98 (2%)

Query: 728 DDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINT 787
           ++ P  PP N+        ++ ++W PP    QNGI+ GY V      +P +  +  I++
Sbjct: 536 EEPPSAPPQNVIASGRTNQSIMIQWQPPPESHQNGILRGYVVRYRLTGLPVDYQLKNISS 595

Query: 788 TVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
                T+L++ +L    +Y +++AA    GLG FS KV
Sbjct: 596 P--DVTNLLLEDLIIWTNYEIEVAAFNGAGLGAFSHKV 631



 Score = 47.6 bits (108), Expect = 0.002
 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 4/107 (3%)

Query: 721  SRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSP-PELQLQ-NGIITGYNVVVNWLDVPA 778
            SR  QTL   PD  P N+ +   + T++ L+W P PE +   N    GY V  +    P 
Sbjct: 965  SRKIQTLPAPPDMAPANVTLRTASETSLWLRWMPLPEWEYNGNAEQVGYRVQYSRAGAP- 1023

Query: 779  NKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
            ++ ++ I  T  Q     + +L   + Y V++ A   IG GP+SQ V
Sbjct: 1024 SRPLIHI-ITDRQEREFTIEDLEEWMEYEVRVQALNGIGAGPWSQPV 1069



 Score = 46.8 bits (106), Expect = 0.004
 Identities = 45/171 (26%), Positives = 72/171 (42%), Gaps = 16/171 (9%)

Query: 661  LEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN 720
            ++G  +YF           ++T+       G ++ +L  YT Y   + PF    +G  S 
Sbjct: 1561 IQGYKVYFWEFQRKNETERLRTLFMPE--GGVKLKNLTGYTTYMISVAPFNAAGDGPRSR 1618

Query: 721  SRVAQTLDDV-PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWL----D 775
             +       V  DG P  I    L TT+V++ W  P     NGII GY +V        +
Sbjct: 1619 RQEGAPSKQVCTDGVPSFIHFSELTTTSVNVSWGEP--AFPNGIIEGYRLVYEPCAPADE 1676

Query: 776  VPANKSMVAINTTVHQATS------LIMTNLTSGVSYSVQIAAETIIGLGP 820
             P + S   ++ TV           L + +L  GV+Y+ +I A+T +  GP
Sbjct: 1677 CPDSPSPPGVSKTVTVDMKGSGPLWLKLRDLADGVTYNFRIRAKTFM-YGP 1726



 Score = 44.8 bits (101), Expect = 0.015
 Identities = 37/129 (28%), Positives = 58/129 (44%), Gaps = 4/129 (3%)

Query: 692  FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751
            F I  L ++ +YE  +        G  S     +T + VP   P N+  F   ++++ ++
Sbjct: 1039 FTIEDLEEWMEYEVRVQALNGIGAGPWSQPVRGRTRESVPSCGPTNVSAFATTSSSILVR 1098

Query: 752  WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT-SLIMTNLTSGVSYSVQI 810
            W       +NG+I GY VV    D   + S V   T    AT S+ +T L   V Y +Q+
Sbjct: 1099 WLEVPDPDRNGLILGYKVVYKEKD---SDSAVHFWTVDGNATHSVQLTGLGKYVLYEIQV 1155

Query: 811  AAETIIGLG 819
             A T +G G
Sbjct: 1156 LAFTRMGDG 1164



 Score = 39.1 bits (87), Expect = 0.72
 Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 1/74 (1%)

Query: 697  LRKYTKYEFFLIPFYKKFEGKPS-NSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPP 755
            L+ +T Y+F +       + + S  S    TL D PD  P  + +    TT+V + W PP
Sbjct: 1372 LKPFTSYQFRVKATNDIGDSEYSAESEAITTLQDAPDEVPAILSVTPHTTTSVLICWKPP 1431

Query: 756  ELQLQNGIITGYNV 769
              +  NGI+ G+ +
Sbjct: 1432 SEEKINGILLGFRI 1445


>UniRef50_Q8IVU1 Cluster: Putative neuronal cell adhesion molecule
           precursor; n=30; Euteleostomi|Rep: Putative neuronal
           cell adhesion molecule precursor - Homo sapiens (Human)
          Length = 814

 Score =  162 bits (394), Expect = 5e-38
 Identities = 126/404 (31%), Positives = 178/404 (44%), Gaps = 29/404 (7%)

Query: 8   SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
           S E  + +E   DV V   QP  L+CR  G+P   I W K GV +   TH ++L  G L 
Sbjct: 39  SAELAFAVEPSDDVAVPG-QPIVLDCRVEGTPPVRITWRKNGVELPESTHSTLLANGSLM 97

Query: 68  F--LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
               R   G   SD G Y C A N +G   SR A +  A +  +F + P++    +G   
Sbjct: 98  IRHFRLEPGGSPSDEGDYECVAQNRFGLVVSRKARIQAATM-SDFHVHPQATVGEEGGVA 156

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
             +C    G P+P + W+KN   +  D + R  L+  G L I   R  D G + C+A N 
Sbjct: 157 RFQC-QIHGLPKPLITWEKNRVPIDTDNE-RYTLLPKGVLQITGLRAEDGGIFHCVASNI 214

Query: 186 AGTRESAIATLKI-------HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238
           A  R S  A L +       + +P ++ GPE++      +   +C   G+P P V W R 
Sbjct: 215 ASIRISHGARLTVSGSGSGAYKEPAILVGPENLTLTVHQTAVLECVATGNPRPIVSWSRL 274

Query: 239 AGGGNMPLG--RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV--SASGYLTVYDPPS 294
            G    P+G   ++VL  G+L + +V +   G Y C A      V  +A G L V  P  
Sbjct: 275 DG---RPIGVEGIQVLGTGNLIISDVTVQHSGVYVCAANRPGTRVRRTAQGRLVVQAPAE 331

Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
               P S++  +G  A FTC A G P P + W   G   ++ PG      H     +  T
Sbjct: 332 FVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQ--VLGPG-----GHVRLKNNNST 384

Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398
            LTI+     D      C A N AGSS    +LTV   +  P P
Sbjct: 385 -LTISGIGPEDEA-IYQCVAENSAGSSQASARLTVLWAEGLPGP 426



 Score =  134 bits (323), Expect = 2e-29
 Identities = 134/518 (25%), Positives = 208/518 (40%), Gaps = 59/518 (11%)

Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
           F +EP    +  G  +VL+C    G+P   + W+KNG  L     +   L+  G+L+I+ 
Sbjct: 44  FAVEPSDDVAVPGQPIVLDCRV-EGTPPVRITWRKNGVEL--PESTHSTLLANGSLMIRH 100

Query: 170 AR------QTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223
            R       +D G Y+C+A+N  G   S  A ++          P+  V + G    FQC
Sbjct: 101 FRLEPGGSPSDEGDYECVAQNRFGLVVSRKARIQAATMSDFHVHPQATVGEEGGVARFQC 160

Query: 224 RVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG-AVS 282
           ++ G P P + W ++    +    R  +L  G L++  +   D G + C A N     +S
Sbjct: 161 QIHGLPKPLITWEKNRVPIDTDNERYTLLPKGVLQITGLRAEDGGIFHCVASNIASIRIS 220

Query: 283 ASGYLTV-------YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII 335
               LTV       Y  P+I + P ++ +     A   C ATG P P + WS    R I 
Sbjct: 221 HGARLTVSGSGSGAYKEPAILVGPENLTLTVHQTAVLECVATGNPRPIVSWSRLDGRPIG 280

Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR---GKLTVTSD 392
             G+            G   L I+D     S    VC+A N  G+   R   G+L V   
Sbjct: 281 VEGIQ---------VLGTGNLIISDVTVQHS-GVYVCAA-NRPGTRVRRTAQGRLVV--- 326

Query: 393 DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGT 451
             + P      P + + P  + A+F C A   P P + W   G+ L    H R   N+ T
Sbjct: 327 --QAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQVLGPGGHVRLKNNNST 384

Query: 452 LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI 511
           L +  +   D   Y CVA +  G    S  L V                  LPGPP    
Sbjct: 385 LTISGIGPEDEAIYQCVAENSAGSSQASARLTV-------------LWAEGLPGPPRNVR 431

Query: 512 THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTH 571
             +V+ T V +SWS+     +  I+GY + +  R+       P        +++   Q  
Sbjct: 432 AVSVSSTEVRVSWSE-PLANTKEIIGYVLHI--RKAAD----PPELEYQEAVSKSTFQ-- 482

Query: 572 YVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
           ++V  L P   Y F ++     G S  S  + + T+G+
Sbjct: 483 HLVSDLEPSTAYSFYIKAYTPRGASSASVPTLASTLGE 520



 Score =  107 bits (258), Expect = 1e-21
 Identities = 88/289 (30%), Positives = 131/289 (45%), Gaps = 21/289 (7%)

Query: 29  ATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFFLRATHGRVHSDAGVYWCEA 87
           A   C+  G P P I W K  V + +D  R ++LP G    L+ T  R   D G++ C A
Sbjct: 156 ARFQCQIHGLPKPLITWEKNRVPIDTDNERYTLLPKG---VLQITGLRAE-DGGIFHCVA 211

Query: 88  TNSYGTARSRNATLHV------AVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVY 141
           +N      S  A L V      A       + PE+       T VLEC+   G+P P V 
Sbjct: 212 SNIASIRISHGARLTVSGSGSGAYKEPAILVGPENLTLTVHQTAVLECVAT-GNPRPIVS 270

Query: 142 WKK-NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR--ESAIATLKI 198
           W + +G+ +  +G   + ++  GNL+I D     +G Y C A N  GTR   +A   L +
Sbjct: 271 WSRLDGRPIGVEG---IQVLGTGNLIISDVTVQHSGVYVCAA-NRPGTRVRRTAQGRLVV 326

Query: 199 HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-L 257
                 +  P+ +    G++  F C+  G+P P V W ++ G    P G V++ ++ S L
Sbjct: 327 QAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKN-GQVLGPGGHVRLKNNNSTL 385

Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
            +  +   DE  Y C AENS G+  AS  LTV     +   P +V   S
Sbjct: 386 TISGIGPEDEAIYQCVAENSAGSSQASARLTVLWAEGLPGPPRNVRAVS 434



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 28/128 (21%), Positives = 55/128 (42%), Gaps = 9/128 (7%)

Query: 639 IEATPIDSKTIKLMWE--ILNFYYLEGLFIYFRPL-DNITIEYEMKTILHSNDVSGFEIT 695
           + A  + S  +++ W   + N   + G  ++ R   D   +EY+      S       ++
Sbjct: 430 VRAVSVSSTEVRVSWSEPLANTKEIIGYVLHIRKAADPPELEYQEAV---SKSTFQHLVS 486

Query: 696 SLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSP- 754
            L   T Y F++  +  +     S   +A TL + P  PP+++   +L ++++ L W P 
Sbjct: 487 DLEPSTAYSFYIKAYTPRGASSASVPTLASTLGEAPAPPPLSVR--VLGSSSLQLLWEPW 544

Query: 755 PELQLQNG 762
           P L    G
Sbjct: 545 PRLAQHEG 552


>UniRef50_Q9UQ52 Cluster: Contactin-6 precursor; n=78;
           Euteleostomi|Rep: Contactin-6 precursor - Homo sapiens
           (Human)
          Length = 1028

 Score =  162 bits (394), Expect = 5e-38
 Identities = 137/490 (27%), Positives = 211/490 (43%), Gaps = 38/490 (7%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
           + P+ +  PLD++ +      LNC A G PSP  RW + G  +           GG   +
Sbjct: 30  QEPHDVIFPLDLSKSE---VILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAI 86

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLE 128
            + H     D G+Y C ATN  GT  SR A L  A + E+F  +  S  S  +G  VVL 
Sbjct: 87  NSPH--TDQDIGMYQCLATNLLGTILSRKAKLQFAYI-EDFETKTRSTVSVREGQGVVLL 143

Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAG 187
           C PP    + +  W  N   L    D+R  +  + GNL I     +D G Y C   N   
Sbjct: 144 CGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEA 203

Query: 188 TRESAIATLKI---------HIKPYL-ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
            R        +           +P + +  PE + A   SSV  +C   G+P+PD+ WRR
Sbjct: 204 QRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRR 263

Query: 238 SAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
              G  +P G+VK     + L + N    DEG Y C A N  G   A G L  Y PP   
Sbjct: 264 -LDGSPLP-GKVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWE 321

Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
               + ++   +   + C A+G+P P   W   G R  + P       + T +   +T+L
Sbjct: 322 QKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGER--LNPEERIQIENGTLI---ITML 376

Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT--LPIKSM 414
            ++D+          C+A N     +   +L V +      P  +  P  +   + +   
Sbjct: 377 NVSDS------GVYQCAAENKYQIIYANAELRVLAS----APDFSKSPVKKKSFVQVGGD 426

Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
            V  C     P   I+W    E L Q+ R  +  DG+L + ++ +SD+G+YTC+A+++ G
Sbjct: 427 IVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFG 486

Query: 475 KYVWSGALLV 484
               +G+L+V
Sbjct: 487 TAKNTGSLIV 496



 Score =  106 bits (254), Expect = 4e-21
 Identities = 164/729 (22%), Positives = 279/729 (38%), Gaps = 85/729 (11%)

Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKK-NGQTLLFDGDSRMHLVDGGNLVIQDARQ 172
           PE+ Q+A+  +V LEC    G+P P++ W++ +G  L   G  + +      L I + +Q
Sbjct: 234 PETIQAAKDSSVKLECFA-LGNPVPDISWRRLDGSPL--PGKVK-YSKSQAILEIPNFQQ 289

Query: 173 TDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
            D G Y+CIA N  G R  A   L  +  P      ++       ++ ++C+  G P P 
Sbjct: 290 EDEGFYECIASNLRG-RNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPW 348

Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-D 291
             W ++    N P  R+++ ++G+L +  + ++D G Y C AEN    + A+  L V   
Sbjct: 349 YTWLKNGERLN-PEERIQI-ENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLAS 406

Query: 292 PPSINLSPNSVN--VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
            P  + SP      V+ G      C     P   + W   G  T+      R       +
Sbjct: 407 APDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWK-RGTETL------RQSKRIFLL 459

Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409
            DG   L I +  ++D+  +  C A N  G++   G L V     +   +IT  PS   +
Sbjct: 460 EDGS--LKIYNITRSDA-GSYTCIATNQFGTAKNTGSLIV-----KERTVITVPPSKMDV 511

Query: 410 PIKSMAVFPCTAICTP--EPIIAWYFEGEALIQN----HRRNVTND--GTLVLKDLDKSD 461
            +    V PC     P  E +  W+F G+ +       H   +  +  G L+++++    
Sbjct: 512 TVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHH 571

Query: 462 SGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVT 521
           SG Y C   +          ++V  P                PGPP      +++ T+  
Sbjct: 572 SGKYLCTVQTTLESLSAVADIIVRGP----------------PGPPEDVQVEDISSTTSQ 615

Query: 522 LSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGI 581
           LSW       S       +++F+ +T     TP  S GW  +A         V  ++ G 
Sbjct: 616 LSWRAGPDNNSP------IQIFTIQT----RTPF-SVGWQAVA--------TVPEILNGK 656

Query: 582 TYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVEL-IE 640
           TY   V      GLS        V  G   NS+  G     S   R       +  + I 
Sbjct: 657 TYNATVV-----GLSPWVEYEFRVVAG---NSIGIGEPSEPSELLRTKASVPVVAPVNIH 708

Query: 641 ATPIDSKTIKLMWEILNFYYLEG----LFIYFRPLDNITIEYEMKTILHSNDVSGFEITS 696
                   + + WE +      G      I FRP+ + T   E  + + S+    +   S
Sbjct: 709 GGGGSRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRFV-YRNES 767

Query: 697 LRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPE 756
           +   + +E  +  +  + EG  S   +  + +D P   P    +   + + + + W+   
Sbjct: 768 IIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIA 827

Query: 757 LQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETII 816
                G + GY V+  W D  + +SM+         T+  +T L +   Y   + A    
Sbjct: 828 WNRNTGRVLGYEVLY-WTD-DSKESMIGKIRVSGNVTTKNITGLKANTIYFASVRAYNTA 885

Query: 817 GLGPFSQKV 825
           G GP S  V
Sbjct: 886 GTGPSSPPV 894



 Score =   99 bits (238), Expect = 4e-19
 Identities = 80/282 (28%), Positives = 124/282 (43%), Gaps = 22/282 (7%)

Query: 33  CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
           C+A G P+P   W K G  + +   R  +  G L           SD+GVY C A N Y 
Sbjct: 339 CKASGKPNPWYTWLKNGERL-NPEERIQIENGTLIITMLNV----SDSGVYQCAAENKYQ 393

Query: 93  TARSRNATLHVAVLREEFRLEPESKQS--AQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
              + NA L V     +F   P  K+S    G  +V+ C  P   P   + WK+  +TL 
Sbjct: 394 IIYA-NAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGC-KPNAFPRAAISWKRGTETLR 451

Query: 151 FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED 210
                R+ L++ G+L I +  ++DAG Y CIA N  GT ++   +L +  +  +   P  
Sbjct: 452 --QSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNT-GSLIVKERTVITVPPSK 508

Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-------RVKVLDDGSLRLDNVI 263
           +    G S+   C+V  DP  +V++     G  + L        R+     G L + N+ 
Sbjct: 509 MDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQ 568

Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
           L   G+Y C  + ++ ++SA   + V  PP     P  V VE
Sbjct: 569 LHHSGKYLCTVQTTLESLSAVADIIVRGPPG---PPEDVQVE 607



 Score = 91.5 bits (217), Expect = 1e-16
 Identities = 78/318 (24%), Positives = 129/318 (40%), Gaps = 15/318 (4%)

Query: 18  PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
           P  +  A+     L C A G+P P I W +   L  S     +  +     L   + +  
Sbjct: 234 PETIQAAKDSSVKLECFALGNPVPDISWRR---LDGSPLPGKVKYSKSQAILEIPNFQ-Q 289

Query: 78  SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
            D G Y C A+N  G   ++   +  A    E+  + ++   +  D ++ EC    G P 
Sbjct: 290 EDEGFYECIASNLRGRNLAKGQLIFYAP--PEWEQKIQNTHLSIYDNLLWEC-KASGKPN 346

Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
           P   W KNG+ L  + + R+  ++ G L+I     +D+G YQC A N      +      
Sbjct: 347 PWYTWLKNGERL--NPEERIQ-IENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRV 403

Query: 198 IHIKPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
           +   P     P  +    Q G  +   C+    P   + W+R          R+ +L+DG
Sbjct: 404 LASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSK-RIFLLEDG 462

Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315
           SL++ N+  +D G Y+C A N  G    +G L V +   I + P+ ++V  G      C 
Sbjct: 463 SLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQ 522

Query: 316 ATGRP--EPTMFWSVEGN 331
            +  P  E    W   G+
Sbjct: 523 VSHDPSIEVVFVWFFNGD 540


>UniRef50_O76518 Cluster: Hemicentin precursor; n=4; Eukaryota|Rep:
            Hemicentin precursor - Caenorhabditis elegans
          Length = 5198

 Score =  161 bits (391), Expect = 1e-37
 Identities = 145/510 (28%), Positives = 222/510 (43%), Gaps = 30/510 (5%)

Query: 23   VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
            VA +QP  + C   G P P+I+W K G  V  D +  I+  G +  +  T       AG 
Sbjct: 3779 VAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDS---DHAGK 3835

Query: 83   YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW 142
            + C A N  G  +     L V        ++ ++   A G+T+ L C    G+P P + W
Sbjct: 3836 WSCVAENDAGV-KELEMVLDVFT-PPVVSVKSDNPIKALGETITLFC-NASGNPYPQLKW 3892

Query: 143  KKNGQTLLFDG-DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201
             K G +L+FD  D     + G  L I   ++TD G Y C A NAAGT E+++ ++ + + 
Sbjct: 3893 AKGG-SLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASV-SVDVLVP 3950

Query: 202  PYLITGPEDVVAQ--TGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LR 258
            P +     D+  +     S+T QC   G P+P + W  +          + V  D + ++
Sbjct: 3951 PEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQ 4010

Query: 259  LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATG 318
            ++NV L+D+G Y+C AEN  G+ +    + V   P I+ +  +  V  G +A   C   G
Sbjct: 4011 INNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVIS-NGGTKQVIEGELAVIECLVEG 4069

Query: 319  RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
             P P + W   GNR  +  G+   +Y    V DG  +LTI +    DS    +CSA N A
Sbjct: 4070 YPAPQVSWLRNGNR--VETGVQGVRY----VTDG-RMLTIIEARSLDS-GIYLCSATNEA 4121

Query: 379  GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438
            GS+     L V       P IIT+ P   T    S    PC     P+PII+W   G  +
Sbjct: 4122 GSAQQAYTLEVLVS----PKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDI 4177

Query: 439  IQNHR-RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRA 497
                    +  DGTL ++  ++     Y C A +  G         V + + P I     
Sbjct: 4178 KDGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLE--FPVQTIVAPKISTSGN 4234

Query: 498  ADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527
              ++   G  T  I   +   S   SWS+N
Sbjct: 4235 RYINGSEGTET-VIKCEIESESSEFSWSKN 4263



 Score =  151 bits (367), Expect = 9e-35
 Identities = 123/446 (27%), Positives = 189/446 (42%), Gaps = 29/446 (6%)

Query: 33   CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
            C   G+P P I WY  G  +  ++    + A     +R       S +GVY C+ATNS G
Sbjct: 1022 CVVSGTPPPIITWYLDGRPITPNSRDFTVTADNTLIVRKAD---KSYSGVYTCQATNSAG 1078

Query: 93   TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFD 152
                +     + ++        +S  +   D +        G P+P + W      LL D
Sbjct: 1079 DNEQKTT---IRIMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITW------LLDD 1129

Query: 153  GDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDV 211
                  +V + G+L I +  +   G + C A+NAAG  ++   TL +H  P +    ++ 
Sbjct: 1130 KPFTEGVVNEDGSLTIPNVNEAHRGTFTCHAQNAAG-NDTRTVTLTVHTTPTINAENQEK 1188

Query: 212  VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYS 271
            +A     +  +C     P P  LW       +  L    + +DG+L L NV L + G + 
Sbjct: 1189 IALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDGALVLQNVKLENTGVFV 1248

Query: 272  CEAENSVGAVSASGYLTVYDPPS-INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
            C+  N  G  S S  LTV++ P  I+  P  V+V  G      C ATG PE    W+  G
Sbjct: 1249 CQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPEVIRTWNKNG 1308

Query: 331  NRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT 390
                I   M   K+      D +  L I + DKND  N   C   N AG+S    ++T  
Sbjct: 1309 ----IDLKMDEKKFSV----DNLGTLRIYEADKNDIGN-YNCVVTNEAGTS----QMTTH 1355

Query: 391  SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT-ND 449
             D   PP I+ +  +N T  +       C    +P   + W+  G A+  + +  V  +D
Sbjct: 1356 VDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRGIAIGTDTKGYVVESD 1415

Query: 450  GTLVLKDLDKSDSGTYTCVASSRHGK 475
            GTLV++     D+  YTC AS+  GK
Sbjct: 1416 GTLVIQSASVEDATIYTCKASNPAGK 1441



 Score =  141 bits (342), Expect = 9e-32
 Identities = 130/510 (25%), Positives = 225/510 (44%), Gaps = 45/510 (8%)

Query: 31   LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
            ++C+  G P P + W + G        + I     +  +R       +D G Y C A+N 
Sbjct: 3236 VHCQVTGRPVPYVTWKRNG--------KEIEQFNPVLHIR---NATRADEGKYSCIASNE 3284

Query: 91   YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
             GTA +    L     +  F     +    +G++  +EC    G P+P + W K G+   
Sbjct: 3285 AGTAVAD--FLIDVFTKPTFETHETTFNIVEGESAKIECKID-GHPKPTISWLKGGRP-- 3339

Query: 151  FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI-TGPE 209
            F+ D+ +    G  L+I  A++ D G Y C+A N+ G  E     + ++ KPY+  T  +
Sbjct: 3340 FNMDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFK-VNVYTKPYIDETIDQ 3398

Query: 210  DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGSLRLDNVILADEG 268
               A  G  +  +C V G+P P V W+R  G   +P   R  ++++  L++++V   D G
Sbjct: 3399 TPKAVAGGEIILKCPVLGNPTPTVTWKR--GDDAVPNDSRHTIVNNYDLKINSVTTEDAG 3456

Query: 269  EYSCEAENSVGAVSASGYLTVYDPPS-INLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327
            +YSC A N  G ++      V   P+ +    N   V   +     C  T RP P++ W 
Sbjct: 3457 QYSCIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPLPSISW- 3515

Query: 328  VEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387
              G++ +       D+Y  +   DG + +TIN    +D     +C A N AG+S +   L
Sbjct: 3516 FRGDKPVYL----YDRYSISP--DG-SHITINKAKLSDG-GKYICRASNEAGTSDIDLIL 3567

Query: 388  TVTSDDDRPPPIITNGPSNQTLPIKSMAVF-PCTAICTPEPIIAWYFEGEALIQNHRRNV 446
             +      PP I  +      L I +  ++  C     P+P + W   G  +     R +
Sbjct: 3568 KILV----PPKIDKSNIIGNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDSRVI 3623

Query: 447  T--NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIH-----FFRAAD 499
               N+ T  ++++  +D G YTC A++R GK     +L V SP   +IH       R  D
Sbjct: 3624 LAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGD 3683

Query: 500  VSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
              +L  P    +  ++ D  + +SW+++++
Sbjct: 3684 TITLTCP--IKLAEDIADQVMDVSWTKDSR 3711



 Score =  138 bits (334), Expect = 9e-31
 Identities = 122/451 (27%), Positives = 185/451 (41%), Gaps = 31/451 (6%)

Query: 27   QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
            Q  TL C A G P P +RW   G  +   T   I  A    F++  +  + SD GVY C 
Sbjct: 3968 QSLTLQCLAQGKPVPQMRWTLNGTALTHSTP-GITVASDSTFIQINNVSL-SDKGVYTCY 4025

Query: 87   ATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146
            A N  G   S N   +V V++        +KQ  +G+  V+ECL   G P P V W +NG
Sbjct: 4026 AENVAG---SDNLMYNVDVVQAPVISNGGTKQVIEGELAVIECLV-EGYPAPQVSWLRNG 4081

Query: 147  QTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT 206
              +        ++ DG  L I +AR  D+G Y C A N AG+ + A  TL++ + P +IT
Sbjct: 4082 NRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAY-TLEVLVSPKIIT 4140

Query: 207  G-PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA 265
              P  +   +GS  +  C V G P P + W  +            +  DG+L ++    A
Sbjct: 4141 STPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEK---A 4197

Query: 266  DEGE--YSCEAENSVGAVSASGYLTVYDPPSINLSPNS-VNVESGNVARFTCTATGRPEP 322
            +E    Y C A+N  GA +    +     P I+ S N  +N   G      C        
Sbjct: 4198 EERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCEIESE-SS 4256

Query: 323  TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
               WS  G      P +  +    +  +  + +L+   +D+ +      C+A N AG++ 
Sbjct: 4257 EFSWSKNG-----VPLLPSNNLIFSEDYKLIKILSTRLSDQGE----YSCTAANKAGNAT 4307

Query: 383  VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN- 441
             +  L V        P I   P  Q +         C A   P+P I WY + E L    
Sbjct: 4308 QKTNLNV-----GVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTG 4362

Query: 442  -HRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
                  T   +++   +  S +G YTC A +
Sbjct: 4363 VDETATTKKKSVIFSSISPSQAGVYTCKAEN 4393



 Score =  137 bits (331), Expect = 2e-30
 Identities = 121/463 (26%), Positives = 195/463 (42%), Gaps = 28/463 (6%)

Query: 29   ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
            A + C   G P+P + W + G  V +          G   L     R   D+G+Y C AT
Sbjct: 4061 AVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRM-LTIIEAR-SLDSGIYLCSAT 4118

Query: 89   NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
            N  G+A+    TL V V  +     P     + G    L C   RG P+P + W  NG  
Sbjct: 4119 NEAGSAQQAY-TLEVLVSPKIITSTPGVLTPSSGSKFSLPCAV-RGYPDPIISWTLNGND 4176

Query: 149  LLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG--TRESAIATLKIHIKPYLIT 206
            +  DG++   +   G L I+ A +     Y+C A+N AG  T E  + T+   + P + T
Sbjct: 4177 IK-DGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTI---VAPKIST 4231

Query: 207  -GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL-RLDNVIL 264
             G   +    G+    +C +  +   +  W ++ G   +P   +   +D  L ++ +  L
Sbjct: 4232 SGNRYINGSEGTETVIKCEIESES-SEFSWSKN-GVPLLPSNNLIFSEDYKLIKILSTRL 4289

Query: 265  ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTM 324
            +D+GEYSC A N  G  +    L V   P I   P +  V  G+     C A+G P+P +
Sbjct: 4290 SDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAI 4349

Query: 325  FWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR 384
             W  + N  +   G+      AT     V   +I+ +          C A N+  S+   
Sbjct: 4350 TW-YKDNELLTNTGVDET---ATTKKKSVIFSSISPSQAG----VYTCKAENWVASTEED 4401

Query: 385  GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR 444
              L V      PP ++    +  T P +      C A   PEP+I+W  +    IQN+ +
Sbjct: 4402 IDLIVMI----PPEVVPERMNVSTNP-RQTVFLSCNATGIPEPVISWMRDSNIAIQNNEK 4456

Query: 445  NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
                  TL ++++   D G Y C+A S  G+ + +  L+V+ P
Sbjct: 4457 YQILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVNKP 4499



 Score =  136 bits (329), Expect = 3e-30
 Identities = 126/472 (26%), Positives = 200/472 (42%), Gaps = 23/472 (4%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
           V + E+P  I    +V+V   + A L+C    +    IRW + G  V +  +    P  G
Sbjct: 514 VETRESPPEIFGVRNVSVPLGEAAFLHCSTRSAGEVEIRWTRYGATVFNGPNTERNPTNG 573

Query: 66  LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
              +   H    +DAGVY C A N+ G + +R   L + +     ++ P+       + V
Sbjct: 574 TLKI---HHVTRADAGVYECMARNAGGMS-TRKMRLDI-MEPPSVKVTPQDVYFNMREGV 628

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
            L C    G P+P V+W   G+ LL D   ++   D   L I+DA   D G Y+C A + 
Sbjct: 629 NLSC-EAMGDPKPEVHWYFKGRHLLNDYKYQVGQ-DSKFLYIRDATHHDEGTYECRAMSQ 686

Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVLWRRSAGGGNM 244
           AG        L +   P +      ++   G  V+F+C+ + G P P + W ++      
Sbjct: 687 AGQARDT-TDLMLATPPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIK 745

Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
           P   +K+ ++G L +      D G YSC  EN  G       L+V   P+I  SP++V V
Sbjct: 746 PDDYIKI-NEGQLHIMGAKDEDAGAYSCVGENMAGKDVQVANLSVGRVPTIIESPHTVRV 804

Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
                    C A G P P + W  +GN  ++   ++  +Y  T + DG   L I D    
Sbjct: 805 NIERQVTLQCLAVGIPPPEIEWQ-KGN--VLLATLNNPRY--TQLADG--NLLITDAQIE 857

Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC- 423
           D +    C A N  G       L VT       P++ + P  + L         C  +  
Sbjct: 858 D-QGQFTCIARNTYGQQSQSTTLMVTG---LVSPVLGHVPPEEQLIEGQDLTLSCVVVLG 913

Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHG 474
           TP+P I W  + + + +     +   G+L+ L+  +  D G YTC+A S  G
Sbjct: 914 TPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEGKYTCIAVSPAG 965



 Score =  135 bits (327), Expect = 6e-30
 Identities = 129/474 (27%), Positives = 202/474 (42%), Gaps = 28/474 (5%)

Query: 14   IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
            ++++  + T   H   TL+C A G P P I W+K G  +  +    I+P G L   +   
Sbjct: 2291 MLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGELNGNQLKI 2350

Query: 74   GRV-HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP 132
             R+   DAG Y CEA NS G+         + + + E    P   +S Q + VV+ C P 
Sbjct: 2351 TRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQQNERVVISC-PV 2409

Query: 133  RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT--RE 190
               P   + W K G+ L  D   +    +G  L +   R+TD+ +Y CIA N AGT  R+
Sbjct: 2410 YARPPAKITWLKAGKPLQSDKFVKTS-ANGQKLYLFKLRETDSSKYTCIATNEAGTDKRD 2468

Query: 191  SAIATL--KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
              ++ L      +P ++     +   +G+  T  C   G P P + W +  G    P  R
Sbjct: 2469 FKVSMLVAPSFDEPNIV---RRITVNSGNPSTLHCPAKGSPSPTITWLKD-GNAIEPNDR 2524

Query: 249  VKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN-LSPNSVNVES 306
                D G  L++     +D+G Y+C A NSVG+      L V  PP I+     +V V  
Sbjct: 2525 YVFFDAGRQLQISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIPPVIDGERREAVAVIE 2584

Query: 307  GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
            G  +   C +       + W  +G  TI    +  D +    +      ++     K+DS
Sbjct: 2585 GFSSELFCDSNS-TGVDVEWQKDG-LTINQDTLRGDSF--IQIPSSGKKMSFLSARKSDS 2640

Query: 367  RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN---QTLPIKSMAVFPCTAIC 423
                 C   N AG +    KL   + +D  PP I++  S+   QT+         C    
Sbjct: 2641 -GRYTCIVRNPAGEA---RKLFDFAVND--PPSISDELSSANIQTIVPYYPVEINCVVSG 2694

Query: 424  TPEPIIAWYFEGEALIQNHRR-NVTNDG-TLVLKDLDKSDSGTYTCVASSRHGK 475
            +P P + W F+ + L  +     +TN+G TL +       +GTYTC A +  GK
Sbjct: 2695 SPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIVRSQVEHAGTYTCEAQNNVGK 2748



 Score =  134 bits (323), Expect = 2e-29
 Identities = 135/505 (26%), Positives = 215/505 (42%), Gaps = 57/505 (11%)

Query: 9    GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGL 66
            G  P IIE P  V V   +  TL C A G P P I W KG VL+  +++   + L  G L
Sbjct: 790  GRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEWQKGNVLLATLNNPRYTQLADGNL 849

Query: 67   FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV-AVLREEFRLEPESKQSAQGDTV 125
                 T  ++  D G + C A N+YG  +S++ TL V  ++       P  +Q  +G  +
Sbjct: 850  LI---TDAQI-EDQGQFTCIARNTYG-QQSQSTTLMVTGLVSPVLGHVPPEEQLIEGQDL 904

Query: 126  VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARN 184
             L C+   G+P+P++ W K+ + +  +    + +  GG+L+ ++     D G+Y CIA +
Sbjct: 905  TLSCVVVLGTPKPSIVWIKDDKPV--EEGPTIKIEGGGSLLRLRGGNPKDEGKYTCIAVS 962

Query: 185  AAGTRESAIATLKIHIKPYLITGPED-----------------VVAQT-----GSSVTFQ 222
             AG     I  +++  KP  +  PE                  VV  T     G      
Sbjct: 963  PAGNSTLHI-NVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEGFAIP 1021

Query: 223  CRVGGDPLPDVLWRRSAGGGNMPLGR-VKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281
            C V G P P + W    G    P  R   V  D +L +     +  G Y+C+A NS G  
Sbjct: 1022 CVVSGTPPPIITWYLD-GRPITPNSRDFTVTADNTLIVRKADKSYSGVYTCQATNSAGDN 1080

Query: 282  SASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341
                 + + + P I+   +S N+   ++    C   G P+P + W ++            
Sbjct: 1081 EQKTTIRIMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLD------------ 1128

Query: 342  DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401
            DK     V +    LTI + ++   R T  C A N AG+       TVT      P I  
Sbjct: 1129 DKPFTEGVVNEDGSLTIPNVNE-AHRGTFTCHAQNAAGND----TRTVTLTVHTTPTI-- 1181

Query: 402  NGPSNQTLPIKS-MAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDK 459
            N  + + + +++   V  C A   P P+  W +EGE +  Q     +  DG LVL+++  
Sbjct: 1182 NAENQEKIALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDGALVLQNVKL 1241

Query: 460  SDSGTYTCVASSRHGKYVWSGALLV 484
             ++G + C  S+  G+   S  L V
Sbjct: 1242 ENTGVFVCQVSNLAGEDSLSYTLTV 1266



 Score =  133 bits (322), Expect = 2e-29
 Identities = 139/501 (27%), Positives = 212/501 (42%), Gaps = 65/501 (12%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPAG 64
            VT   +P +   P +  +   Q  TL+C    G+P P+I W K    V       I   G
Sbjct: 881  VTGLVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIKIEGGG 940

Query: 65   GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVL---REEFRLEPES----- 116
             L  LR  + +   D G Y C A +  G     N+TLH+ V    + EF  +PE      
Sbjct: 941  SLLRLRGGNPK---DEGKYTCIAVSPAG-----NSTLHINVQLIKKPEFVYKPEGGIVFK 992

Query: 117  --------KQSA---------QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL 159
                    K  A          G+   + C+   G+P P + W  +G+ +    +SR   
Sbjct: 993  PTISGMDEKHVAVVNSTHDVLDGEGFAIPCVVS-GTPPPIITWYLDGRPIT--PNSRDFT 1049

Query: 160  VDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSS 218
            V   N L+++ A ++ +G Y C A N+AG  E    T++I   P +  G           
Sbjct: 1050 VTADNTLIVRKADKSYSGVYTCQATNSAGDNEQK-TTIRIMNTPMISPGQSSFNMVVDDL 1108

Query: 219  VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSV 278
             T  C V GDP P + W       + P     V +DGSL + NV  A  G ++C A+N+ 
Sbjct: 1109 FTIPCDVYGDPKPVITWLLD----DKPFTEGVVNEDGSLTIPNVNEAHRGTFTCHAQNAA 1164

Query: 279  GAVSASGYLTVYDPPSINL-SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR--TII 335
            G  + +  LTV+  P+IN  +   + +++ ++    C A   P P   W+ EG +  + +
Sbjct: 1165 GNDTRTVTLTVHTTPTINAENQEKIALQNDDIV-LECPAKALPPPVRLWTYEGEKIDSQL 1223

Query: 336  FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395
             P   R+        DG  VL      K ++    VC   N AG   +   LTV      
Sbjct: 1224 IPHTIRE--------DGALVL---QNVKLENTGVFVCQVSNLAGEDSLSYTLTV----HE 1268

Query: 396  PPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLV 453
             P II+  P    + +K   +  PC A   PE I  W   G  L  + ++ +V N GTL 
Sbjct: 1269 KPKIISEVPGVVDV-VKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDEKKFSVDNLGTLR 1327

Query: 454  LKDLDKSDSGTYTCVASSRHG 474
            + + DK+D G Y CV ++  G
Sbjct: 1328 IYEADKNDIGNYNCVVTNEAG 1348



 Score =  133 bits (321), Expect = 3e-29
 Identities = 129/477 (27%), Positives = 195/477 (40%), Gaps = 40/477 (8%)

Query: 3    DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
            D YV   E P ++     + V   +  T+ C   G+P P + W K G    SD  +    
Sbjct: 3118 DTYVEISEPPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKDGEPYTSDLLQFSTK 3177

Query: 63   AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSA 120
               L  LR T     +D G Y C ATN  G +++   T  V VL    R+E E +  Q  
Sbjct: 3178 LSYL-HLRET---TLADGGTYTCIATNKAGESQT---TTDVEVLVPP-RIEDEERVLQGK 3229

Query: 121  QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
            +G+T ++ C    G P P V WK+NG+ +      + + V    L I++A + D G+Y C
Sbjct: 3230 EGNTYMVHC-QVTGRPVPYVTWKRNGKEI-----EQFNPV----LHIRNATRADEGKYSC 3279

Query: 181  IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
            IA N AGT   A   + +  KP   T         G S   +C++ G P P + W +  G
Sbjct: 3280 IASNEAGT-AVADFLIDVFTKPTFETHETTFNIVEGESAKIECKIDGHPKPTISWLK--G 3336

Query: 241  GGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS- 298
            G    +  + +   G +L +      D G Y+C A NS G       + VY  P I+ + 
Sbjct: 3337 GRPFNMDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETI 3396

Query: 299  PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
              +    +G      C   G P PT+ W   G+  +  P  SR  +     +D    L I
Sbjct: 3397 DQTPKAVAGGEIILKCPVLGNPTPTVTWK-RGDDAV--PNDSR--HTIVNNYD----LKI 3447

Query: 359  NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
            N     D+     C AVN AG+        V       P  +  G +   +         
Sbjct: 3448 NSVTTEDA-GQYSCIAVNEAGNLTTHYAAEVIG----KPTFVRKGGNLYEVIENDTITMD 3502

Query: 419  CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHG 474
            C     P P I+W+   + +    R +++ DG+ + +     SD G Y C AS+  G
Sbjct: 3503 CGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAKLSDGGKYICRASNEAG 3559



 Score =  128 bits (310), Expect = 7e-28
 Identities = 129/484 (26%), Positives = 191/484 (39%), Gaps = 35/484 (7%)

Query: 23   VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
            V  +   T++C     P P+I W++G   V      SI P G    +        SD G 
Sbjct: 3493 VIENDTITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAK---LSDGGK 3549

Query: 83   YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLECLPPRGSPEPNVY 141
            Y C A+N  GT+   +  L + V  +  +        A    T+ LEC P  G P+P+V 
Sbjct: 3550 YICRASNEAGTS-DIDLILKILVPPKIDKSNIIGNPLAIVARTIYLEC-PISGIPQPDVI 3607

Query: 142  WKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
            W KNG  +    DSR+ L        I++ + TD GRY C A N  G      +   +  
Sbjct: 3608 WTKNGMDINMT-DSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSP 3666

Query: 201  KPYLITGPEDVVAQTGSSVTFQCRVG-----GDPLPDVLWRRSAGGGNMPL-GRVKVLDD 254
              + I G +  + + G ++T  C +       D + DV W + +   +  L   V + DD
Sbjct: 3667 PEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDD 3726

Query: 255  G-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV--NVESGNVAR 311
            G  L +    L + G Y+C A N  G  S    + +  PP I++S N V   V       
Sbjct: 3727 GRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQPTI 3786

Query: 312  FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371
              C  TG P P++ W   G           D  +   V  G  VL I  TD +D      
Sbjct: 3787 MRCAVTGHPFPSIKWLKNGKEV-------TDDENIRIVEQG-QVLQILRTD-SDHAGKWS 3837

Query: 372  CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431
            C A N AG   +   L V +     PP+++    N    +       C A   P P + W
Sbjct: 3838 CVAENDAGVKELEMVLDVFT-----PPVVSVKSDNPIKALGETITLFCNASGNPYPQLKW 3892

Query: 432  YFEGEALIQ--NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPIN 489
               G  +    +  R       L +  L K+D G YTC A +  G      ++ VD  + 
Sbjct: 3893 AKGGSLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAG--TSEASVSVDVLVP 3950

Query: 490  PNIH 493
            P I+
Sbjct: 3951 PEIN 3954



 Score =  124 bits (299), Expect = 1e-26
 Identities = 109/455 (23%), Positives = 187/455 (41%), Gaps = 20/455 (4%)

Query: 22   TVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAG 81
            T+  + P  +NC   GSP P + W      +  D+    L   G   L+    +V   AG
Sbjct: 2679 TIVPYYPVEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGET-LKIVRSQVEH-AG 2736

Query: 82   VYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVY 141
             Y CEA N+ G AR ++  + V      F  E E   +  GDT++L C      P  +VY
Sbjct: 2737 TYTCEAQNNVGKAR-KDFLVRVTA-PPHFEKEREEVVARVGDTMLLTCNAESSVPLSSVY 2794

Query: 142  WKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201
            W  + +++     +  +  +   L + + +  D G Y C A N AG  +     + I   
Sbjct: 2795 WHAHDESVQNGVITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIE-T 2853

Query: 202  PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDN 261
            PY +   +      G  +T  C   G P P +L+ +     N     V ++   +L +DN
Sbjct: 2854 PYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLN-ESDEVDII-GSTLVIDN 2911

Query: 262  VILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPE 321
                 EG Y+C AEN  G       + V  PP ++    +V V++G+     C       
Sbjct: 2912 PQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKEWINVEVQAGDPLTLECPIEDTSG 2971

Query: 322  PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381
              + WS +  +       ++     + ++  +   T  D D      +  C AVN AG +
Sbjct: 2972 VHITWSRQFGKDGQLDMRAQSSSDKSKLY--IMQATPEDAD------SYSCIAVNDAGGA 3023

Query: 382  FVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN 441
                ++TV +    PP I  +  S   +   +    PC     P P I+W+ +G+ +++ 
Sbjct: 3024 EAVFQVTVNT----PPKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFLDGKPILEM 3079

Query: 442  HRRNV-TNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
                    D +L + ++  +  G YTCVA ++ G+
Sbjct: 3080 PGVTYKQGDLSLRIDNIKPNQEGRYTCVAENKAGR 3114



 Score =  123 bits (297), Expect = 3e-26
 Identities = 115/417 (27%), Positives = 170/417 (40%), Gaps = 27/417 (6%)

Query: 79  DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
           DAG Y C   ++ G    +          E F +   S     G+   L C   R + E 
Sbjct: 493 DAGEYECRVISNNGNYSVKTRVETRESPPEIFGVRNVSVPL--GEAAFLHC-STRSAGEV 549

Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
            + W + G T+ F+G +       G L I    + DAG Y+C+ARNA G     +  L I
Sbjct: 550 EIRWTRYGATV-FNGPNTERNPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMR-LDI 607

Query: 199 HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-L 257
              P +   P+DV       V   C   GDP P+V W    G   +   + +V  D   L
Sbjct: 608 MEPPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFK-GRHLLNDYKYQVGQDSKFL 666

Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC-TA 316
            + +    DEG Y C A +  G    +  L +  PP + +  N + V  G+   F C T 
Sbjct: 667 YIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKMMVGRGDRVSFECKTI 726

Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
            G+P P + W   G + +I P    D Y    + +G   L I    K++      C   N
Sbjct: 727 RGKPHPKIRWFKNG-KDLIKP----DDY--IKINEGQ--LHIMGA-KDEDAGAYSCVGEN 776

Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436
            AG       L+V     R P II + P    + I+      C A+  P P I W  +G 
Sbjct: 777 MAGKDVQVANLSV----GRVPTIIES-PHTVRVNIERQVTLQCLAVGIPPPEIEWQ-KGN 830

Query: 437 ALI---QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
            L+    N R     DG L++ D    D G +TC+A + +G+   S  L+V   ++P
Sbjct: 831 VLLATLNNPRYTQLADGNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVSP 887



 Score =  121 bits (292), Expect = 1e-25
 Identities = 109/470 (23%), Positives = 184/470 (39%), Gaps = 32/470 (6%)

Query: 6    VTSGEAPYIIEQPLDVT-VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
            VT    P I       T +       + CR  G P P I W+  G  ++      +    
Sbjct: 3029 VTVNTPPKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFLDGKPILEMP--GVTYKQ 3086

Query: 65   GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
            G   LR  + + + + G Y C A N  G A  ++  + ++       +  E  +  +G  
Sbjct: 3087 GDLSLRIDNIKPNQE-GRYTCVAENKAGRAE-QDTYVEISE-PPRVVMASEVMRVVEGRQ 3143

Query: 125  VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
              + C    G+PEP V W K+G+   +  D          L +++    D G Y CIA N
Sbjct: 3144 TTIRC-EVFGNPEPVVNWLKDGEP--YTSDLLQFSTKLSYLHLRETTLADGGTYTCIATN 3200

Query: 185  AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
             AG  ++    +++ + P +      +  + G++    C+V G P+P V W+R+      
Sbjct: 3201 KAGESQTT-TDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRN------ 3253

Query: 245  PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
              G+     +  L + N   ADEG+YSC A N  G   A   + V+  P+      + N+
Sbjct: 3254 --GKEIEQFNPVLHIRNATRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNI 3311

Query: 305  ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
              G  A+  C   G P+PT+ W ++G R       + D    +   D + +L     D  
Sbjct: 3312 VEGESAKIECKIDGHPKPTISW-LKGGRP-----FNMDNIILSPRGDTLMILKAQRFD-- 3363

Query: 365  DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
                   C A N  G S    K+ V +     P I                +  C  +  
Sbjct: 3364 --GGLYTCVATNSYGDSEQDFKVNVYT----KPYIDETIDQTPKAVAGGEIILKCPVLGN 3417

Query: 425  PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
            P P + W    +A+  + R  + N+  L +  +   D+G Y+C+A +  G
Sbjct: 3418 PTPTVTWKRGDDAVPNDSRHTIVNNYDLKINSVTTEDAGQYSCIAVNEAG 3467



 Score =  120 bits (288), Expect = 3e-25
 Identities = 121/466 (25%), Positives = 184/466 (39%), Gaps = 32/466 (6%)

Query: 30   TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
            T+ C   G P P I W    +L        ++   G   +   +    +  G + C A N
Sbjct: 1110 TIPCDVYGDPKPVITW----LLDDKPFTEGVVNEDGSLTIPNVN---EAHRGTFTCHAQN 1162

Query: 90   SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
            + G   +R  TL V         E + K + Q D +VLEC P +  P P   W   G+ +
Sbjct: 1163 AAGND-TRTVTLTVHTT-PTINAENQEKIALQNDDIVLEC-PAKALPPPVRLWTYEGEKI 1219

Query: 150  LFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208
              D     H + + G LV+Q+ +  + G + C   N AG  +S   TL +H KP +I+  
Sbjct: 1220 --DSQLIPHTIREDGALVLQNVKLENTGVFVCQVSNLAG-EDSLSYTLTVHEKPKIISEV 1276

Query: 209  EDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267
              VV    G ++   CR  G P     W ++     M   +  V + G+LR+      D 
Sbjct: 1277 PGVVDVVKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDEKKFSVDNLGTLRIYEADKNDI 1336

Query: 268  GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE-SGNVARFTCTATGRPEPTMFW 326
            G Y+C   N  G    + ++ V +PP I  S  + N    G+     C     P  ++ W
Sbjct: 1337 GNYNCVVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTW 1396

Query: 327  SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
               G    I  G     Y    V +    L I      D+     C A N AG +    +
Sbjct: 1397 FRRG----IAIGTDTKGY----VVESDGTLVIQSASVEDA-TIYTCKASNPAGKAEANLQ 1447

Query: 387  LTV-TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN 445
            +TV  S D + P ++T     ++ P        C     P P I+WY   + LI +    
Sbjct: 1448 VTVIASPDIKDPDVVTQESIKESHPFS----LYCPVFSNPLPQISWYLNDKPLIDDKTSW 1503

Query: 446  VTNDGTLVLKDLDK--SDSGTYTCVASSRHGKYVWSGALLVDSPIN 489
             T+D    L       +DSG Y CVA +  G+   S  + V  P+N
Sbjct: 1504 KTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLN 1549



 Score =  120 bits (288), Expect = 3e-25
 Identities = 121/472 (25%), Positives = 188/472 (39%), Gaps = 38/472 (8%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            E PY ++Q     +   +  TL+C A G+P P I + K G  +       I+  G    +
Sbjct: 2852 ETPYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDII--GSTLVI 2909

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
                  V    G Y C A N  G  RS    +   +L  +   E  + +   GD + LEC
Sbjct: 2910 DNPQKEVE---GRYTCIAENKAG--RSEKDMMVEVLLPPKLSKEWINVEVQAGDPLTLEC 2964

Query: 130  LPPRGSPEPNVYWKKN-GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
             P   +   ++ W +  G+    D  ++    D   L I  A   DA  Y CIA N AG 
Sbjct: 2965 -PIEDTSGVHITWSRQFGKDGQLDMRAQSSS-DKSKLYIMQATPEDADSYSCIAVNDAGG 3022

Query: 189  RESAIATLKIHIKPYLIT---GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
             E A+  + ++  P +        ++VA T  ++   CR  G P P++ W          
Sbjct: 3023 AE-AVFQVTVNTPPKIFGDSFSTTEIVADT--TLEIPCRTEGIPPPEISWFLDGKPILEM 3079

Query: 246  LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
             G      D SLR+DN+    EG Y+C AEN  G      Y+ + +PP + ++   + V 
Sbjct: 3080 PGVTYKQGDLSLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEISEPPRVVMASEVMRVV 3139

Query: 306  SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
             G      C   G PEP + W  +G      P  S     +T     ++ L + +T   D
Sbjct: 3140 EGRQTTIRCEVFGNPEPVVNWLKDGE-----PYTSDLLQFSTK----LSYLHLRETTLAD 3190

Query: 366  SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
               T  C A N AG S      T T  +   PP I +          +  +  C     P
Sbjct: 3191 G-GTYTCIATNKAGES-----QTTTDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRP 3244

Query: 426  EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
             P + W   G+ + Q        +  L +++  ++D G Y+C+AS+  G  V
Sbjct: 3245 VPYVTWKRNGKEIEQ-------FNPVLHIRNATRADEGKYSCIASNEAGTAV 3289



 Score =  118 bits (285), Expect = 7e-25
 Identities = 128/483 (26%), Positives = 203/483 (42%), Gaps = 61/483 (12%)

Query: 23   VARHQPATLNCRA-GGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAG 81
            V R    +  C+   G P P IRW+K G  ++       +  G L  +    G    DAG
Sbjct: 713  VGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIKINEGQLHIM----GAKDEDAG 768

Query: 82   VYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSPEPNV 140
             Y C   N  G         +++V R    +E P + +      V L+CL   G P P +
Sbjct: 769  AYSCVGENMAGKDVQ---VANLSVGRVPTIIESPHTVRVNIERQVTLQCLAV-GIPPPEI 824

Query: 141  YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH- 199
             W+K    L    + R   +  GNL+I DA+  D G++ CIARN  G ++S   TL +  
Sbjct: 825  EWQKGNVLLATLNNPRYTQLADGNLLITDAQIEDQGQFTCIARNTYG-QQSQSTTLMVTG 883

Query: 200  -IKPYLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGNMPLGR---VKVLDD 254
             + P L   P +     G  +T  C V  G P P ++W +     + P+     +K+   
Sbjct: 884  LVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKD----DKPVEEGPTIKIEGG 939

Query: 255  GS-LRLDNVILADEGEYSCEAENSVG--AVSASGYLT-----VYDPP-SINLSPNSVNVE 305
            GS LRL      DEG+Y+C A +  G   +  +  L      VY P   I   P    ++
Sbjct: 940  GSLLRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMD 999

Query: 306  SGNVA--------------RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
              +VA                 C  +G P P + W ++G    I P  SRD +  TA   
Sbjct: 1000 EKHVAVVNSTHDVLDGEGFAIPCVVSGTPPPIITWYLDGRP--ITPN-SRD-FTVTA--- 1052

Query: 352  GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
                L +   DK+ S     C A N AG +  +  + + +      P+I+ G S+  + +
Sbjct: 1053 -DNTLIVRKADKSYS-GVYTCQATNSAGDNEQKTTIRIMN-----TPMISPGQSSFNMVV 1105

Query: 412  KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
              +   PC     P+P+I W  + +   +     V  DG+L + +++++  GT+TC A +
Sbjct: 1106 DDLFTIPCDVYGDPKPVITWLLDDKPFTEG---VVNEDGSLTIPNVNEAHRGTFTCHAQN 1162

Query: 472  RHG 474
              G
Sbjct: 1163 AAG 1165



 Score =  116 bits (278), Expect = 5e-24
 Identities = 125/466 (26%), Positives = 191/466 (40%), Gaps = 28/466 (6%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
            ++TV   +  TL C    +    I W   G   +++T      AGG F L     +   D
Sbjct: 2015 ELTVNLTRSITLECDVDDAIGVGISWTVNGKPFLAETDGVQTLAGGRF-LHIVSAKT-DD 2072

Query: 80   AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
             G Y C  TN  G A ++   L V V       E       + +++VL C    G P P 
Sbjct: 2073 HGSYACTVTNEAGVA-TKTFNLFVQVPPTIVN-EGGEYTVIENNSLVLPC-EVTGKPNPV 2129

Query: 140  VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
            V W K+G+ +  D  S   L +G    I  A     G Y C+A+N  GT E +   + I 
Sbjct: 2130 VTWTKDGRPV-GDLKSVQVLSEGQQFKIVHAEIAHKGSYICMAKNDVGTAEISF-DVDII 2187

Query: 200  IKPYLITGPEDVV-AQTGSSVTFQCRVGGDP--LPDVLWRRSAGGGNMPLGRVKVL---D 253
             +P +  G +++V A  G ++ F+C +  D      ++W R+    ++     ++    +
Sbjct: 2188 TRPMIQKGIKNIVTAIKGGALPFKCPIDDDKNFKGQIIWLRNYQPIDLEAEDARITRLSN 2247

Query: 254  DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI---NLSPNSVNVESGNVA 310
            D  L + NV   DEG+YSC  +N  G  S     TV  PP+I   +   N   VE   V 
Sbjct: 2248 DRRLTILNVTENDEGQYSCRVKNDAGENSFDFKATVLVPPTIIMLDKDKNKTAVEHSTVT 2307

Query: 311  RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
              +C ATG+PEP + W  +G   I    ++    +     + + +  I + D        
Sbjct: 2308 -LSCPATGKPEPDITWFKDG-EAIHIENIADIIPNGELNGNQLKITRIKEGD----AGKY 2361

Query: 371  VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG-PSNQTLPIKSMAVFPCTAICTPEPII 429
             C A N AGS      + V +     P I  +G PS+         V  C     P   I
Sbjct: 2362 TCEADNSAGSVEQDVNVNVIT----IPKIEKDGIPSDYESQQNERVVISCPVYARPPAKI 2417

Query: 430  AWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
             W   G+ L      +   N   L L  L ++DS  YTC+A++  G
Sbjct: 2418 TWLKAGKPLQSDKFVKTSANGQKLYLFKLRETDSSKYTCIATNEAG 2463



 Score =  110 bits (264), Expect = 3e-22
 Identities = 114/460 (24%), Positives = 188/460 (40%), Gaps = 45/460 (9%)

Query: 31   LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
            L C    SP  ++ W++ G+ + +DT   ++ + G   +++       DA +Y C+A+N 
Sbjct: 1382 LKCYVEASPPASVTWFRRGIAIGTDTKGYVVESDGTLVIQSASVE---DATIYTCKASNP 1438

Query: 91   YGTARSRNATLHVAVLREEFRLEPE---SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
             G A    A L V V+      +P+    +   +     L C P   +P P + W  N +
Sbjct: 1439 AGKAE---ANLQVTVIASPDIKDPDVVTQESIKESHPFSLYC-PVFSNPLPQISWYLNDK 1494

Query: 148  TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT-----RESAIATLKIHIKP 202
             L+ D  S     D   L +  A+ TD+G Y+C+ARNAAG      +   I  L +    
Sbjct: 1495 PLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLNLDESK 1554

Query: 203  YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW---RRSAGGGNMPLGRVKVLDDGSLRL 259
            Y     + V A+ G  VT  C V G P+P + W         G    G     D  +L  
Sbjct: 1555 Y----KKKVFAKEGEEVTLGCPVSGFPVPQINWVVDGTVVEPGKKYKGATLSNDGLTLHF 1610

Query: 260  DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC-TATG 318
            D+V +  EG Y C A++    +     L+V   P +    N + V  G     +C   T 
Sbjct: 1611 DSVSVKQEGNYHCVAQSKGNILDIDVELSVLAVPIVGEDDN-LEVFLGKDISLSCDLQTE 1669

Query: 319  RPEPTMF-WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
              + T F WS+ G+ +        D+     +      L I D  K ++    +C   N 
Sbjct: 1670 SDDKTTFVWSINGSES--------DRPDNVQIPSDGHRLYITDA-KPENNGKYMCRVTNS 1720

Query: 378  AGSSFVRGKLTVTSDDDRPPPIITN-GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436
            AG    + + T+T D   PP  +     +NQ L   +  +  C     P+P + W  +G 
Sbjct: 1721 AG----KAERTLTLDVLEPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKIDGN 1776

Query: 437  ALIQNHRRNVTNDGTLVLKDLDK--SDSGTYTCVASSRHG 474
             +     ++   D +L L  ++K    S   +C A ++ G
Sbjct: 1777 DV----DKSWLFDESLSLLRIEKLTGKSAQISCTAENKAG 1812



 Score =  104 bits (249), Expect = 2e-20
 Identities = 98/387 (25%), Positives = 144/387 (37%), Gaps = 20/387 (5%)

Query: 14   IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
            I   P  +T +     +L C   G P P I W   G  +    +   + A G   +    
Sbjct: 4139 ITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKAE 4198

Query: 74   GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
             R H    +Y C A N  G A +    +   V  +           ++G   V++C    
Sbjct: 4199 ER-HL---IYECTAKNDAG-ADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCEIES 4253

Query: 134  GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
             S E +  W KNG  LL   ++ +   D   + I   R +D G Y C A N AG      
Sbjct: 4254 ESSEFS--WSKNGVPLL-PSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQK- 4309

Query: 194  ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVL 252
              L + + P ++  P   V   G  VT  C   G P P + W +      N  +      
Sbjct: 4310 TNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATT 4369

Query: 253  DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARF 312
               S+   ++  +  G Y+C+AEN V +      L V  PP +     +V+         
Sbjct: 4370 KKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFL 4429

Query: 313  TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
            +C ATG PEP + W  + N  I     + +KY         T L I +   +D      C
Sbjct: 4430 SCNATGIPEPVISWMRDSNIAI----QNNEKYQILG-----TTLAIRNVLPDDD-GFYHC 4479

Query: 373  SAVNYAGSSFVRGKLTVTSDDDRPPPI 399
             A + AG      KL V    DRP PI
Sbjct: 4480 IAKSDAGQKIATRKLIVNKPSDRPAPI 4506



 Score = 98.3 bits (234), Expect = 1e-18
 Identities = 109/363 (30%), Positives = 152/363 (41%), Gaps = 31/363 (8%)

Query: 6    VTSGEAPYII-EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPA 63
            +T  E P II E P  V V +     + CRA G P     W K G+ L + +   S+   
Sbjct: 1264 LTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDEKKFSVDNL 1323

Query: 64   GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL--EPESKQSAQ 121
            G L    A      +D G Y C  TN  GT++    T HV V      L     +  +  
Sbjct: 1324 GTLRIYEAD----KNDIGNYNCVVTNEAGTSQ---MTTHVDVQEPPIILPSTQTNNTAVV 1376

Query: 122  GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQC 180
            GD V L+C     SP  +V W + G  +    D++ ++V+  G LVIQ A   DA  Y C
Sbjct: 1377 GDRVELKCY-VEASPPASVTWFRRG--IAIGTDTKGYVVESDGTLVIQSASVEDATIYTC 1433

Query: 181  IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQ----TGSSVTFQCRVGGDPLPDVLWR 236
             A N AG  E   A L++ +         DVV Q         +  C V  +PLP + W 
Sbjct: 1434 KASNPAGKAE---ANLQVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQISWY 1490

Query: 237  RSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295
             +           K  DD   L +    + D G Y C A N+ G  S S  + V  P ++
Sbjct: 1491 LNDKPLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLNL 1550

Query: 296  NLS--PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH-ATAVFDG 352
            + S     V  + G      C  +G P P + W V+G  T++ PG    KY  AT   DG
Sbjct: 1551 DESKYKKKVFAKEGEEVTLGCPVSGFPVPQINWVVDG--TVVEPG---KKYKGATLSNDG 1605

Query: 353  VTV 355
            +T+
Sbjct: 1606 LTL 1608



 Score = 97.5 bits (232), Expect = 2e-18
 Identities = 87/342 (25%), Positives = 139/342 (40%), Gaps = 23/342 (6%)

Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC--IARNAAGTRESAIATLK 197
           +YW K G+ ++  G    H  D     I +    DAG Y+C  I+ N   + ++ + T +
Sbjct: 460 IYWVKTGEDII-GGPLFYHNTDTSVWTIPELSLKDAGEYECRVISNNGNYSVKTRVETRE 518

Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR-SAGGGNMPLGRVKVLDDGS 256
               P  I G  +V    G +    C        ++ W R  A   N P    +   +G+
Sbjct: 519 ---SPPEIFGVRNVSVPLGEAAFLHCSTRSAGEVEIRWTRYGATVFNGP-NTERNPTNGT 574

Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316
           L++ +V  AD G Y C A N+ G  +    L + +PPS+ ++P  V          +C A
Sbjct: 575 LKIHHVTRADAGVYECMARNAGGMSTRKMRLDIMEPPSVKVTPQDVYFNMREGVNLSCEA 634

Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
            G P+P + W  +G        ++  KY    V      L I D   +D   T  C A++
Sbjct: 635 MGDPKPEVHWYFKGRHL-----LNDYKYQ---VGQDSKFLYIRDATHHD-EGTYECRAMS 685

Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI-CTPEPIIAWYFEG 435
            AG +     L + +     PP +    +   +       F C  I   P P I W+  G
Sbjct: 686 QAGQARDTTDLMLAT-----PPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKIRWFKNG 740

Query: 436 EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
           + LI+       N+G L +      D+G Y+CV  +  GK V
Sbjct: 741 KDLIKPDDYIKINEGQLHIMGAKDEDAGAYSCVGENMAGKDV 782



 Score = 93.5 bits (222), Expect = 3e-17
 Identities = 106/471 (22%), Positives = 181/471 (38%), Gaps = 34/471 (7%)

Query: 10   EAPYIIEQPLDVT--VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
            E P  +E   +    +  + P  L C+  G+P P + W   G    +D  +S L    L 
Sbjct: 1734 EPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKIDG----NDVDKSWLFDESLS 1789

Query: 68   FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ-SAQGDTVV 126
             LR    ++   +    C A N  GTA SR+  +   +    F+ E + +    + +T+ 
Sbjct: 1790 LLRIE--KLTGKSAQISCTAENKAGTA-SRDFFIQ-NIAAPTFKNEGDQETIFRESETIT 1845

Query: 127  LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
            L+C  P    +  + W K G  L  + D+ +  +D   L I +A +     Y C+A N A
Sbjct: 1846 LDC--PVSLGDFQITWMKQGLPLT-ENDA-IFTLDNTRLTILNANRDHEDIYTCVANNTA 1901

Query: 187  GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
            G + S    + + + P +      +    G  +   C   G+P P   W      G++P 
Sbjct: 1902 G-QVSKDFDVVVQVLPKIKNAVVTLEINEGEEIILTCDAEGNPTPTAKW--DFNQGDLPK 1958

Query: 247  GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNV 304
              V V ++ ++ ++NV     G Y C A N VG    +  + V   P     L+ + + V
Sbjct: 1959 EAVFVNNNHTVVVNNVTKYHTGVYKCYATNKVGQAVKTINVHVRTKPRFESGLTESELTV 2018

Query: 305  ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
                     C         + W+V G      P ++  +        G   L I    K 
Sbjct: 2019 NLTRSITLECDVDDAIGVGISWTVNGK-----PFLA--ETDGVQTLAGGRFLHIVSA-KT 2070

Query: 365  DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
            D   +  C+  N AG +     L V     + PP I N     T+   +  V PC     
Sbjct: 2071 DDHGSYACTVTNEAGVATKTFNLFV-----QVPPTIVNEGGEYTVIENNSLVLPCEVTGK 2125

Query: 425  PEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
            P P++ W  +G  +       V ++G    +   + +  G+Y C+A +  G
Sbjct: 2126 PNPVVTWTKDGRPVGDLKSVQVLSEGQQFKIVHAEIAHKGSYICMAKNDVG 2176



 Score = 92.7 bits (220), Expect = 6e-17
 Identities = 114/453 (25%), Positives = 176/453 (38%), Gaps = 45/453 (9%)

Query: 38   SPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
            S S    W K GV ++   +        L  + +T     SD G Y C A N  G A ++
Sbjct: 4253 SESSEFSWSKNGVPLLPSNNLIFSEDYKLIKILSTR---LSDQGEYSCTAANKAGNA-TQ 4308

Query: 98   NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM 157
               L+V V  +     P ++   +GD V L C    G P+P + W K+ + L   G    
Sbjct: 4309 KTNLNVGVAPKIME-RPRTQVVHKGDQVTLWC-EASGVPQPAITWYKDNELLTNTGVDET 4366

Query: 158  HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGS 217
                  +++      + AG Y C A N   + E  I  L + I P ++    +V      
Sbjct: 4367 ATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDI-DLIVMIPPEVVPERMNVSTNPRQ 4425

Query: 218  SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENS 277
            +V   C   G P P + W R +        + ++L   +L + NV+  D+G Y C A++ 
Sbjct: 4426 TVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGT-TLAIRNVLPDDDGFYHCIAKSD 4484

Query: 278  VGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337
             G   A+  L V  P      P  + VE        C   G+P+ T +        +I  
Sbjct: 4485 AGQKIATRKLIVNKPSD---RPAPIWVE--------CDEKGKPKKTEY--------MIDR 4525

Query: 338  GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397
            G + D        D   +L   D + +    +I      Y      R   TV       P
Sbjct: 4526 GDTPD--------DNPQLLPWKDVEDSSLNGSIA-----YRCMPGPRSSRTVLLH--AAP 4570

Query: 398  PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL 457
              I   P N T  I ++    C+A   P P I W  +G+ LI++ +  +      V  + 
Sbjct: 4571 QFIVK-PKNTTAAIGAIVELRCSAAGPPHPTITWAKDGK-LIEDSKFEIAYSHLKVTLN- 4627

Query: 458  DKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
              SDSG YTC+A +  G    S  + VD+ I P
Sbjct: 4628 STSDSGEYTCMAQNSVGSSTVSAFINVDNNILP 4660



 Score = 89.8 bits (213), Expect = 4e-16
 Identities = 124/473 (26%), Positives = 194/473 (41%), Gaps = 62/473 (13%)

Query: 9    GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD--THRSILPAGGL 66
            G AP I+E+P    V +    TL C A G P PAI WYK   L+ +      +      +
Sbjct: 4315 GVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATTKKKSV 4374

Query: 67   FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
             F   +     S AGVY C+A N +  +   +  L + ++  E   E  +  +    TV 
Sbjct: 4375 IFSSIS----PSQAGVYTCKAEN-WVASTEEDIDL-IVMIPPEVVPERMNVSTNPRQTVF 4428

Query: 127  LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
            L C    G PEP + W ++    + + +   + + G  L I++    D G Y CIA++ A
Sbjct: 4429 LSC-NATGIPEPVISWMRDSNIAIQNNEK--YQILGTTLAIRNVLPDDDGFYHCIAKSDA 4485

Query: 187  GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD--VLWRRSAGGGNM 244
            G +   IAT K+     ++  P D  A     +  +C   G P     ++ R      N 
Sbjct: 4486 GQK---IATRKL-----IVNKPSDRPA----PIWVECDEKGKPKKTEYMIDRGDTPDDNP 4533

Query: 245  PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
             L   K ++D SL   N  +A    Y C     +    +S  + ++  P   + P +   
Sbjct: 4534 QLLPWKDVEDSSL---NGSIA----YRC-----MPGPRSSRTVLLHAAPQFIVKPKNTTA 4581

Query: 305  ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
              G +    C+A G P PT+ W+ +G   +I        Y    V       T+N T  +
Sbjct: 4582 AIGAIVELRCSAAGPPHPTITWAKDGK--LIEDSKFEIAYSHLKV-------TLNST--S 4630

Query: 365  DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC-TAIC 423
            DS     C A N  GSS V   + V  ++  P P      SNQ    K++AV  C     
Sbjct: 4631 DS-GEYTCMAQNSVGSSTVSAFINV-DNNILPTP---KPSSNQ----KNVAVITCYERNQ 4681

Query: 424  TPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKD---LDKSDSGTYTCVASSR 472
                 + W + G  + +N    +  N+G+LV+ D   L + D   YTC   +R
Sbjct: 4682 AYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNR 4734



 Score = 88.2 bits (209), Expect = 1e-15
 Identities = 88/309 (28%), Positives = 130/309 (42%), Gaps = 26/309 (8%)

Query: 11   APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
            AP  I +P + T A      L C A G P P I W K G L + D+   I  +     L 
Sbjct: 4569 APQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKL-IEDSKFEIAYSHLKVTLN 4627

Query: 71   ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
            +T     SD+G Y C A NS G     ++T+   +  +   L      S Q +  V+ C 
Sbjct: 4628 ST-----SDSGEYTCMAQNSVG-----SSTVSAFINVDNNILPTPKPSSNQKNVAVITCY 4677

Query: 131  PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA---RQTDAGRYQCIARNAAG 187
                +    + W+ NG  +     + +H ++ G+LVI D    ++ D   Y C  RN   
Sbjct: 4678 ERNQAYSRGLTWEYNGVPMP-KNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRN--- 4733

Query: 188  TRESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPL-PDVLWRRSAGGGNM 244
             R  +I  L    +  P + T  + V    G SV   C V  DPL   V+W ++     +
Sbjct: 4734 RRRHSIPHLTSAFEGVPEVKT-IDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKN-DQKML 4791

Query: 245  PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP---PSINLSPNS 301
                + VL + SL L NV   DEG Y C A NS+G       L VY+    P      + 
Sbjct: 4792 DDDAIYVLPNNSLVLLNVEKYDEGVYKCVASNSIGKAFDDTQLNVYEGDFLPLTGFEGSG 4851

Query: 302  VNVESGNVA 310
            +N++  + A
Sbjct: 4852 INIDDSSNA 4860



 Score = 82.2 bits (194), Expect = 8e-14
 Identities = 109/467 (23%), Positives = 178/467 (38%), Gaps = 52/467 (11%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P ++ + ++V+    Q   L+C A G P P I W +   + + +  +  +    L    A
Sbjct: 4410 PEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTL----A 4465

Query: 72   THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
                +  D G Y C A +  G    + AT  + V +   R  P          + +EC  
Sbjct: 4466 IRNVLPDDDGFYHCIAKSDAG---QKIATRKLIVNKPSDRPAP----------IWVEC-D 4511

Query: 132  PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
             +G P+   Y    G T     D    L+   +  ++D+    +  Y+C+     G R S
Sbjct: 4512 EKGKPKKTEYMIDRGDT----PDDNPQLLPWKD--VEDSSLNGSIAYRCMP----GPRSS 4561

Query: 192  AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
               T+ +H  P  I  P++  A  G+ V  +C   G P P + W   A  G +       
Sbjct: 4562 R--TVLLHAAPQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITW---AKDGKLIEDSKFE 4616

Query: 252  LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVAR 311
            +    L++     +D GEY+C A+NSVG+ + S ++ V +       P+S      NVA 
Sbjct: 4617 IAYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSS---NQKNVAV 4673

Query: 312  FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD--KNDSRNT 369
             TC    +       +     T  + G+   K  A   F     L I DT   K      
Sbjct: 4674 ITCYERNQ-------AYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLEL 4726

Query: 370  IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP-EPI 428
              C   N    S       +TS  +  P + T       +      V  C     P    
Sbjct: 4727 YTCKVRNRRRHSIPH----LTSAFEGVPEVKT--IDKVEVNNGDSVVLDCEVTSDPLTTH 4780

Query: 429  IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
            + W    + ++ +    V  + +LVL +++K D G Y CVAS+  GK
Sbjct: 4781 VVWTKNDQKMLDDDAIYVLPNNSLVLLNVEKYDEGVYKCVASNSIGK 4827



 Score = 77.8 bits (183), Expect = 2e-12
 Identities = 79/334 (23%), Positives = 134/334 (40%), Gaps = 20/334 (5%)

Query: 3    DDYVTSGEAPYIIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL 61
            D ++ +  AP    +    T+ R  +  TL+C         I W K G+ +  +     L
Sbjct: 1817 DFFIQNIAAPTFKNEGDQETIFRESETITLDCPVSLGDFQ-ITWMKQGLPLTENDAIFTL 1875

Query: 62   PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
                L  L A   R H D  +Y C A N+ G   S++  + V VL  + +    + +  +
Sbjct: 1876 DNTRLTILNAN--RDHED--IYTCVANNTAGQV-SKDFDVVVQVL-PKIKNAVVTLEINE 1929

Query: 122  GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
            G+ ++L C    G+P P   W  N   L  +    + + +   +V+ +  +   G Y+C 
Sbjct: 1930 GEEIILTC-DAEGNPTPTAKWDFNQGDLPKEA---VFVNNNHTVVVNNVTKYHTGVYKCY 1985

Query: 182  ARNAAGTRESAIATLKIHI--KPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
            A N  G    A+ T+ +H+  KP   +G    ++      S+T +C V       + W  
Sbjct: 1986 ATNKVG---QAVKTINVHVRTKPRFESGLTESELTVNLTRSITLECDVDDAIGVGISWTV 2042

Query: 238  SAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
            +          V+ L  G  L + +    D G Y+C   N  G  + +  L V  PP+I 
Sbjct: 2043 NGKPFLAETDGVQTLAGGRFLHIVSAKTDDHGSYACTVTNEAGVATKTFNLFVQVPPTIV 2102

Query: 297  LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
                   V   N     C  TG+P P + W+ +G
Sbjct: 2103 NEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDG 2136



 Score = 76.6 bits (180), Expect = 4e-12
 Identities = 120/515 (23%), Positives = 196/515 (38%), Gaps = 46/515 (8%)

Query: 27   QPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85
            +  TL C   G P P I W   G +V     ++    +     L      V  + G Y C
Sbjct: 1565 EEVTLGCPVSGFPVPQINWVVDGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQE-GNYHC 1623

Query: 86   EATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC-LPPRGSPEPNVYWKK 144
             A +        +  + ++VL      E ++ +   G  + L C L      +    W  
Sbjct: 1624 VAQSK---GNILDIDVELSVLAVPIVGEDDNLEVFLGKDISLSCDLQTESDDKTTFVWSI 1680

Query: 145  NGQTLLFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY 203
            NG     D    + +  DG  L I DA+  + G+Y C   N+AG  E  + TL + ++P 
Sbjct: 1681 NGSE--SDRPDNVQIPSDGHRLYITDAKPENNGKYMCRVTNSAGKAERTL-TLDV-LEPP 1736

Query: 204  LITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG-SLRL 259
            +   P     Q     + +  QC+V G+P P V+W+     GN  + +  + D+  SL  
Sbjct: 1737 VFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKID---GN-DVDKSWLFDESLSLLR 1792

Query: 260  DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV--ESGNVARFTCTAT 317
               +     + SC AEN  G  S   ++     P+     +   +  ES  +      + 
Sbjct: 1793 IEKLTGKSAQISCTAENKAGTASRDFFIQNIAAPTFKNEGDQETIFRESETITLDCPVSL 1852

Query: 318  GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
            G  + T  W  +G      P    D   A    D  T LTI + ++ D  +   C A N 
Sbjct: 1853 GDFQIT--WMKQG-----LPLTEND---AIFTLDN-TRLTILNANR-DHEDIYTCVANNT 1900

Query: 378  AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437
            AG       + V     +  P I N      +      +  C A   P P   W F  + 
Sbjct: 1901 AGQVSKDFDVVV-----QVLPKIKNAVVTLEINEGEEIILTCDAEGNPTPTAKWDF-NQG 1954

Query: 438  LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRA 497
             +      V N+ T+V+ ++ K  +G Y C A+++ G+ V +    ++  +     F   
Sbjct: 1955 DLPKEAVFVNNNHTVVVNNVTKYHTGVYKCYATNKVGQAVKT----INVHVRTKPRFESG 2010

Query: 498  ADVSSLPGPPTKPIT--HNVTDT-SVTLSWSQNNK 529
               S L    T+ IT   +V D   V +SW+ N K
Sbjct: 2011 LTESELTVNLTRSITLECDVDDAIGVGISWTVNGK 2045


>UniRef50_UPI00005BDC8C Cluster: PREDICTED: similar to hemicentin;
            n=1; Bos taurus|Rep: PREDICTED: similar to hemicentin -
            Bos taurus
          Length = 2756

 Score =  161 bits (390), Expect = 1e-37
 Identities = 152/538 (28%), Positives = 230/538 (42%), Gaps = 31/538 (5%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
            V +G  P ++  P +VTV+  + A L+C         + W +   ++ + T R    A  
Sbjct: 962  VVTGPPPQLVPVP-NVTVSPGETAILSCLVLSEAPYNLTWVRDWRVLSASTGRVTQLADL 1020

Query: 66   LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDT 124
               +R T     SD G Y C A+NS G  R   A++ + V    +  +   S++ +QG  
Sbjct: 1021 SLEVRNT---TPSDGGRYQCMASNSNGVTR---ASVWLLVREAPQVSIHTRSQRFSQGME 1074

Query: 125  VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
            V + C    G P P++ W + G+ L    DSR+ +   G L+IQ     DAG Y C A N
Sbjct: 1075 VRVRC-SASGYPAPHISWSREGRAL--QEDSRVRVDAQGTLIIQGVAPEDAGSYSCQAAN 1131

Query: 185  AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
              G R+    TL     P +      V+A  G     +C   G P P V+W R  G   M
Sbjct: 1132 EIG-RDEETVTLYYTDPPSVSAVNGVVLAAKGEEAVLECEATGVPPPRVIWYR--GDLEM 1188

Query: 245  PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
             L     +  G LR+  V   D G Y+C A N +G  SA   L V   P +   P  V V
Sbjct: 1189 ILAPEDSI-SGMLRIPVVRERDAGVYTCRAVNELGDASAEIRLEVGHAPQLLELPQDVTV 1247

Query: 305  ESGNVARFTCTATGRPEPTMFWSVEGNRTI-IFPGMSRDKYHATAVFDGVTVLTINDTDK 363
            E G  A   C ATG P PT+ W    ++ + + PG SR  +  + V    +V+       
Sbjct: 1248 ELGRSALLACRATGHPLPTITWHRGDDQPLGLRPG-SRTGWPDSGVLFFESVVP------ 1300

Query: 364  NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
             + +   VC A N  G       L VT     PP I ++ P+ + L  + +++ PC  + 
Sbjct: 1301 -EDQALYVCEAENVFGKVQAEAYLLVTG--HVPPQIASSAPTVRVLERQPVSL-PCIVLA 1356

Query: 424  -TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482
              P P   W   G  L    R ++  DG+L L      D+G Y+CV S+  G +     L
Sbjct: 1357 GRPRPERRWLKAGMPLPPGSRHSIRADGSLHLDQALLEDAGRYSCVVSNTAGSHHRDVQL 1416

Query: 483  LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQV 540
            +V  P  P I       +++   P + P   +   T  T++W++     +S    Y V
Sbjct: 1417 VVQVP--PRIQPTATHHITNEGVPASLPCVASGVPTP-TITWTKETNALASRDPHYNV 1471



 Score =  157 bits (381), Expect = 2e-36
 Identities = 130/479 (27%), Positives = 194/479 (40%), Gaps = 34/479 (7%)

Query: 9    GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG--VLVVSDTHRSILPAGGL 66
            G AP ++E P DVTV   + A L CRA G P P I W++G    L +    R+  P  G+
Sbjct: 1233 GHAPQLLELPQDVTVELGRSALLACRATGHPLPTITWHRGDDQPLGLRPGSRTGWPDSGV 1292

Query: 67   FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
             F  +    V  D  +Y CEA N +G  ++    L    +  +      + +  +   V 
Sbjct: 1293 LFFESV---VPEDQALYVCEAENVFGKVQAEAYLLVTGHVPPQIASSAPTVRVLERQPVS 1349

Query: 127  LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
            L C+   G P P   W K G  L     SR  +   G+L +  A   DAGRY C+  N A
Sbjct: 1350 LPCIVLAGRPRPERRWLKAGMPL--PPGSRHSIRADGSLHLDQALLEDAGRYSCVVSNTA 1407

Query: 187  GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
            G+    +  L + + P +       +   G   +  C   G P P + W +         
Sbjct: 1408 GSHHRDV-QLVVQVPPRIQPTATHHITNEGVPASLPCVASGVPTPTITWTKETNALASRD 1466

Query: 247  GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS-------P 299
                V  DG+L +    + D G Y C A N+VG  S    L+V   P I ++       P
Sbjct: 1467 PHYNVSKDGTLVIPRPSVQDAGAYVCTATNAVGFSSQEMRLSVNTKPRILVNGSHEADKP 1526

Query: 300  NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
              V  ++G+     C A G P P + W+ +    +       D++H          L + 
Sbjct: 1527 LRVTAKAGDEVTLDCEAQGSPPPLVTWTKDSRHMLPI----TDRHHLLPPGS----LHLA 1578

Query: 360  DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419
                +DS     C+A N AGS+     L V     + PP +  GP    + +       C
Sbjct: 1579 QAQVSDS-GLYECTASNPAGSATQYYILRV-----QVPPQVQPGPRVLKVLVGEAVDLNC 1632

Query: 420  TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVW 478
             A  +PEP + W  +G AL     R    +G++    +  S +GTY C ASS  G   W
Sbjct: 1633 VAEGSPEPRVTWSKDGVAL-----RGEGPEGSVHFAAIQTSHAGTYRCEASSSAGVDAW 1686



 Score =  155 bits (377), Expect = 5e-36
 Identities = 140/477 (29%), Positives = 191/477 (40%), Gaps = 33/477 (6%)

Query: 21   VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
            V  A+ + A L C A G P P + WY+G + ++     SI    G+  +     R   DA
Sbjct: 1157 VLAAKGEEAVLECEATGVPPPRVIWYRGDLEMILAPEDSI---SGMLRIPVVRER---DA 1210

Query: 81   GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
            GVY C A N  G A S    L V    +   L P+      G + +L C    G P P +
Sbjct: 1211 GVYTCRAVNELGDA-SAEIRLEVGHAPQLLEL-PQDVTVELGRSALLACRAT-GHPLPTI 1267

Query: 141  YWKK-NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG-TRESAIATLKI 198
             W + + Q L     SR    D G L  +     D   Y C A N  G  +  A   +  
Sbjct: 1268 TWHRGDDQPLGLRPGSRTGWPDSGVLFFESVVPEDQALYVCEAENVFGKVQAEAYLLVTG 1327

Query: 199  HIKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257
            H+ P + +    V       V+  C V  G P P+  W + AG    P  R  +  DGSL
Sbjct: 1328 HVPPQIASSAPTVRVLERQPVSLPCIVLAGRPRPERRWLK-AGMPLPPGSRHSIRADGSL 1386

Query: 258  RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
             LD  +L D G YSC   N+ G+      L V  PP I  +        G  A   C A+
Sbjct: 1387 HLDQALLEDAGRYSCVVSNTAGSHHRDVQLVVQVPPRIQPTATHHITNEGVPASLPCVAS 1446

Query: 318  GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
            G P PT+ W+ E N        SRD  H     DG   L I      D+    VC+A N 
Sbjct: 1447 GVPTPTITWTKETNAL-----ASRDP-HYNVSKDG--TLVIPRPSVQDA-GAYVCTATNA 1497

Query: 378  AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA------VFPCTAICTPEPIIAW 431
             G S    +L+V +     P I+ NG      P++  A         C A  +P P++ W
Sbjct: 1498 VGFSSQEMRLSVNT----KPRILVNGSHEADKPLRVTAKAGDEVTLDCEAQGSPPPLVTW 1553

Query: 432  YFEGEALIQ-NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
              +   ++    R ++   G+L L     SDSG Y C AS+  G       L V  P
Sbjct: 1554 TKDSRHMLPITDRHHLLPPGSLHLAQAQVSDSGLYECTASNPAGSATQYYILRVQVP 1610



 Score =  153 bits (370), Expect = 4e-35
 Identities = 147/534 (27%), Positives = 221/534 (41%), Gaps = 50/534 (9%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
            +V V    P    C A G P+P I W+K G  +V  T       G    L    G   SD
Sbjct: 2128 EVAVMEGHPVWFLCEARGVPTPDITWFKDGDPLVPSTEVVYTRGGRQLQLERAQG---SD 2184

Query: 80   AGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
            AG Y C+A+N+ G   ++    ++V    E     P   ++  G  + LEC+  RG P P
Sbjct: 2185 AGTYSCKASNAVGVVEKTTRLEVYVPPTIEGTGEGPRVVKAVAGRPLTLECV-ARGYPPP 2243

Query: 139  NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI-ATLK 197
             V W   G  ++ D +       GG L ++   +   G Y C+A + AG  E+ +  +++
Sbjct: 2244 TVSWYHEGLPVV-DRNGTWLGAGGGVLSLESLGEASGGLYSCVASSPAG--EAVLHYSVE 2300

Query: 198  IHIKPYLIT--GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
            + + P L+   G   V    G S+   C   G P+P + W ++ G     L  V V  +G
Sbjct: 2301 VQVAPQLLVAEGLGQVTTLVGQSLYLPCYASGSPVPTIQWLQN-GHPAEELPGVHVTSEG 2359

Query: 256  -SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL-SPNSVNVESGNVARFT 313
             +L +D+V L   G ++C+A N  G  +A   L+V++ PS+ +    ++           
Sbjct: 2360 TTLHIDHVELGHAGLFACQATNEAGTAAAEVELSVHELPSVVIVGGENITAPFLQPVTLR 2419

Query: 314  CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
            C  TG P P++ W  +G               A A   G   L I   D  D   T  C 
Sbjct: 2420 CAGTGVPTPSLRWWKDG--------------VALAASGG--SLQIEKVDLKD-EGTYTCV 2462

Query: 374  AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF 433
            A N AG S     L V       PP I  G  N+ +   +     C A   P P I+W+ 
Sbjct: 2463 ATNLAGESRKEVILRVL-----VPPNIEPGLVNKAVLENASVTLECLASGVPPPDISWFK 2517

Query: 434  EGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
              + +    R  V+ DG  L+++    SD+G+Y CVAS+  G      +L V+ P  P I
Sbjct: 2518 GRQPISAWDRAMVSTDGRVLLIEQAQLSDAGSYRCVASNVVGSTELQYSLRVNVP--PRI 2575

Query: 493  HFFRAADVSSLPGP-----PTKPITHNVTDTSVTLSW-SQNNKIGSSSILGYQV 540
                     SLPGP     P +         S  L W    N + ++   G QV
Sbjct: 2576 TL-----PPSLPGPVLLHSPVRLTCDAAGAPSPMLMWLKDGNPVSTAGTAGLQV 2624



 Score =  134 bits (324), Expect = 1e-29
 Identities = 140/470 (29%), Positives = 204/470 (43%), Gaps = 43/470 (9%)

Query: 16   EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75
            E P  V     +P TL C A G P P + WY  G+ VV D + + L AGG      + G 
Sbjct: 2218 EGPRVVKAVAGRPLTLECVARGYPPPTVSWYHEGLPVV-DRNGTWLGAGGGVLSLESLGE 2276

Query: 76   VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDTVVLECLPPRG 134
              +  G+Y C A++  G A   + ++ V V  +    E   + +   G ++ L C    G
Sbjct: 2277 --ASGGLYSCVASSPAGEA-VLHYSVEVQVAPQLLVAEGLGQVTTLVGQSLYLPCYAS-G 2332

Query: 135  SPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
            SP P + W +NG     +    +H+  +G  L I       AG + C A N AGT  +A 
Sbjct: 2333 SPVPTIQWLQNGHPA--EELPGVHVTSEGTTLHIDHVELGHAGLFACQATNEAGT-AAAE 2389

Query: 194  ATLKIHIKP-YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL 252
              L +H  P  +I G E++ A     VT +C   G P P + W +         G     
Sbjct: 2390 VELSVHELPSVVIVGGENITAPFLQPVTLRCAGTGVPTPSLRWWKD--------GVALAA 2441

Query: 253  DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN---VESGNV 309
              GSL+++ V L DEG Y+C A N  G       L V  PP  N+ P  VN   +E+ +V
Sbjct: 2442 SGGSLQIEKVDLKDEGTYTCVATNLAGESRKEVILRVLVPP--NIEPGLVNKAVLENASV 2499

Query: 310  ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
                C A+G P P + W  +G +    P  + D+  A    DG  VL I     +D+  +
Sbjct: 2500 T-LECLASGVPPPDISW-FKGRQ----PISAWDR--AMVSTDG-RVLLIEQAQLSDA-GS 2549

Query: 370  IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPS-NQTLPIKSMAVFPCTAICTPEPI 428
              C A N  GS+ ++  L V       PP IT  PS    + + S     C A   P P+
Sbjct: 2550 YRCVASNVVGSTELQYSLRV-----NVPPRITLPPSLPGPVLLHSPVRLTCDAAGAPSPM 2604

Query: 429  IAWYFEGEALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
            + W  +G  +       +        L+L     SDSG+Y+CVA S  G+
Sbjct: 2605 LMWLKDGNPVSTAGTAGLQVFPGGRVLMLASARVSDSGSYSCVAVSAVGE 2654



 Score =  132 bits (318), Expect = 7e-29
 Identities = 104/335 (31%), Positives = 139/335 (41%), Gaps = 21/335 (6%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRA-GGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
            VT    P I      V V   QP +L C    G P P  RW K G+ +   +  SI   G
Sbjct: 1325 VTGHVPPQIASSAPTVRVLERQPVSLPCIVLAGRPRPERRWLKAGMPLPPGSRHSIRADG 1384

Query: 65   GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ--SAQG 122
             L   +A    +  DAG Y C  +N+ G+   R+  L V V     R++P +    + +G
Sbjct: 1385 SLHLDQA----LLEDAGRYSCVVSNTAGS-HHRDVQLVVQVPP---RIQPTATHHITNEG 1436

Query: 123  DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
                L C+   G P P + W K    L    D   ++   G LVI      DAG Y C A
Sbjct: 1437 VPASLPCVAS-GVPTPTITWTKETNALA-SRDPHYNVSKDGTLVIPRPSVQDAGAYVCTA 1494

Query: 183  RNAAGTRESAIATLKIHIKP-YLITG------PEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
             NA G     +  L ++ KP  L+ G      P  V A+ G  VT  C   G P P V W
Sbjct: 1495 TNAVGFSSQEMR-LSVNTKPRILVNGSHEADKPLRVTAKAGDEVTLDCEAQGSPPPLVTW 1553

Query: 236  RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295
             + +        R  +L  GSL L    ++D G Y C A N  G+ +    L V  PP +
Sbjct: 1554 TKDSRHMLPITDRHHLLPPGSLHLAQAQVSDSGLYECTASNPAGSATQYYILRVQVPPQV 1613

Query: 296  NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
               P  + V  G      C A G PEP + WS +G
Sbjct: 1614 QPGPRVLKVLVGEAVDLNCVAEGSPEPRVTWSKDG 1648



 Score =  130 bits (314), Expect = 2e-28
 Identities = 123/435 (28%), Positives = 172/435 (39%), Gaps = 43/435 (9%)

Query: 21   VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
            VT    Q   L C A GSP P I+W + G          +   G    L   H  +   A
Sbjct: 2316 VTTLVGQSLYLPCYASGSPVPTIQWLQNGHPAEELPGVHVTSEGTT--LHIDHVEL-GHA 2372

Query: 81   GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
            G++ C+ATN  GTA +    L V  L     +  E+  +     V L C    G P P++
Sbjct: 2373 GLFACQATNEAGTAAAE-VELSVHELPSVVIVGGENITAPFLQPVTLRCAGT-GVPTPSL 2430

Query: 141  YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
             W K+G  L            GG+L I+     D G Y C+A N AG     +  L++ +
Sbjct: 2431 RWWKDGVALA---------ASGGSLQIEKVDLKDEGTYTCVATNLAGESRKEVI-LRVLV 2480

Query: 201  KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---RVKVLDDGS- 256
             P +  G  +      +SVT +C   G P PD+ W +    G  P+    R  V  DG  
Sbjct: 2481 PPNIEPGLVNKAVLENASVTLECLASGVPPPDISWFK----GRQPISAWDRAMVSTDGRV 2536

Query: 257  LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN-VESGNVARFTCT 315
            L ++   L+D G Y C A N VG+      L V  PP I L P+    V   +  R TC 
Sbjct: 2537 LLIEQAQLSDAGSYRCVASNVVGSTELQYSLRVNVPPRITLPPSLPGPVLLHSPVRLTCD 2596

Query: 316  ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
            A G P P + W  +GN       +S        VF G  VL +     +DS  +  C AV
Sbjct: 2597 AAGAPSPMLMWLKDGNP------VSTAGTAGLQVFPGGRVLMLASARVSDS-GSYSCVAV 2649

Query: 376  NYAGSSFVRGKLTVTSDDDRP------------PPIITNGPSNQTLPIKSMAVFPCTAIC 423
            +  G       L V S+   P            PP I     N ++         C +  
Sbjct: 2650 SAVGEDRRDVVLRVHSESRAPEAAGCGLEAQDAPPSILGEEQNVSVVANESVALECRSHA 2709

Query: 424  TPEPIIAWYFEGEAL 438
             P P+++W  +G  L
Sbjct: 2710 VPPPVLSWRKDGRPL 2724



 Score =  122 bits (293), Expect = 8e-26
 Identities = 107/419 (25%), Positives = 166/419 (39%), Gaps = 28/419 (6%)

Query: 78   SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS-AQGDTVVLECLPPRGSP 136
            ++ G Y C A +  GT R++     + V     +L P    + + G+T +L CL    +P
Sbjct: 939  AEEGTYECTAVSRAGTGRAKT---QIVVTGPPPQLVPVPNVTVSPGETAILSCLVLSEAP 995

Query: 137  EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
              N+ W ++ + L         L D  +L +++   +D GRYQC+A N+ G   +++  L
Sbjct: 996  Y-NLTWVRDWRVLSASTGRVTQLAD-LSLEVRNTTPSDGGRYQCMASNSNGVTRASV-WL 1052

Query: 197  KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS 256
             +   P +           G  V  +C   G P P + W R  G       RV+V   G+
Sbjct: 1053 LVREAPQVSIHTRSQRFSQGMEVRVRCSASGYPAPHISWSRE-GRALQEDSRVRVDAQGT 1111

Query: 257  LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316
            L +  V   D G YSC+A N +G    +  L   DPPS++     V    G  A   C A
Sbjct: 1112 LIIQGVAPEDAGSYSCQAANEIGRDEETVTLYYTDPPSVSAVNGVVLAAKGEEAVLECEA 1171

Query: 317  TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
            TG P P + W   G+  +I            A  D ++ +      +        C AVN
Sbjct: 1172 TGVPPPRVIW-YRGDLEMIL-----------APEDSISGMLRIPVVRERDAGVYTCRAVN 1219

Query: 377  YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436
              G +    +L V        P +   P + T+ +   A+  C A   P P I W+   +
Sbjct: 1220 ELGDASAEIRLEVGH-----APQLLELPQDVTVELGRSALLACRATGHPLPTITWHRGDD 1274

Query: 437  ---ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
                L    R    + G L  + +   D   Y C A +  GK      LLV   + P I
Sbjct: 1275 QPLGLRPGSRTGWPDSGVLFFESVVPEDQALYVCEAENVFGKVQAEAYLLVTGHVPPQI 1333



 Score =  109 bits (263), Expect = 3e-22
 Identities = 92/284 (32%), Positives = 132/284 (46%), Gaps = 21/284 (7%)

Query: 37   GSPSPAIRWYKG--GVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTA 94
            G+P P + W KG     +      ++L  G LF    +     SD G Y C+ATN  G+A
Sbjct: 1813 GTPKPQVTWRKGPSSEPLRDRPGLAVLDEGSLFLASVSP----SDGGDYECQATNEAGSA 1868

Query: 95   RSRNATLHVAV---LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLF 151
             SR A L V V   LRE+ R    S  +  G ++ LEC    G P P + W KNG+ +  
Sbjct: 1869 -SRRAKLVVHVPPSLREDGRRANVSGMA--GQSLTLEC-DANGFPAPEITWLKNGRQIPA 1924

Query: 152  DGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI--TGP 208
             G  R  L+DG   L     ++ D+G Y C A N AGT +     L + I P ++     
Sbjct: 1925 VGSHR--LLDGARALHFPRIQEGDSGLYSCRAENQAGTAQRDFDLLVL-IPPSVLGAEAA 1981

Query: 209  EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADE 267
            ++VV   G+    +CR  G P P V W +      +   RV++ +DG  LR+ N  L DE
Sbjct: 1982 QEVVGLAGAGAELECRTLGVPTPQVEWTKDGQPVFLGEPRVQLQEDGQVLRITNSHLGDE 2041

Query: 268  GEYSCEAENSVGAVSASGYLTVYDPPS-INLSPNSVNVESGNVA 310
            G Y C A +  G  +    L ++  PS    SP + +   G +A
Sbjct: 2042 GWYQCVAFSPAGQQTKDFQLRIHGEPSPFPSSPRAAHCVEGWLA 2085



 Score =   99 bits (238), Expect = 4e-19
 Identities = 86/309 (27%), Positives = 127/309 (41%), Gaps = 20/309 (6%)

Query: 167  IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVG 226
            I  A + + G Y+C A + AGT  +    +     P L+  P +V    G +    C V 
Sbjct: 933  IPRASKAEEGTYECTAVSRAGTGRAKTQIVVTGPPPQLVPVP-NVTVSPGETAILSCLVL 991

Query: 227  GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY 286
             +   ++ W R     +   GRV  L D SL + N   +D G Y C A NS G   AS +
Sbjct: 992  SEAPYNLTWVRDWRVLSASTGRVTQLADLSLEVRNTTPSDGGRYQCMASNSNGVTRASVW 1051

Query: 287  LTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHA 346
            L V + P +++   S     G   R  C+A+G P P + WS EG R +      R     
Sbjct: 1052 LLVREAPQVSIHTRSQRFSQGMEVRVRCSASGYPAPHISWSREG-RALQEDSRVRVDAQG 1110

Query: 347  TAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN 406
            T +  GV           +   +  C A N  G    R + TVT     PP +  +  + 
Sbjct: 1111 TLIIQGVA---------PEDAGSYSCQAANEIG----RDEETVTLYYTDPPSV--SAVNG 1155

Query: 407  QTLPIK-SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465
              L  K   AV  C A   P P + WY     +I     +++  G L +  + + D+G Y
Sbjct: 1156 VVLAAKGEEAVLECEATGVPPPRVIWYRGDLEMILAPEDSIS--GMLRIPVVRERDAGVY 1213

Query: 466  TCVASSRHG 474
            TC A +  G
Sbjct: 1214 TCRAVNELG 1222



 Score = 94.3 bits (224), Expect = 2e-17
 Identities = 61/203 (30%), Positives = 95/203 (46%), Gaps = 9/203 (4%)

Query: 134  GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
            G+P+P V W+K   +        + ++D G+L +     +D G Y+C A N AG+  S  
Sbjct: 1813 GTPKPQVTWRKGPSSEPLRDRPGLAVLDEGSLFLASVSPSDGGDYECQATNEAGS-ASRR 1871

Query: 194  ATLKIHIKPYLITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP-LGRVK 250
            A L +H+ P L       +V    G S+T +C   G P P++ W ++  G  +P +G  +
Sbjct: 1872 AKLVVHVPPSLREDGRRANVSGMAGQSLTLECDANGFPAPEITWLKN--GRQIPAVGSHR 1929

Query: 251  VLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE--SG 307
            +LD   +L    +   D G YSC AEN  G       L V  PPS+  +  +  V   +G
Sbjct: 1930 LLDGARALHFPRIQEGDSGLYSCRAENQAGTAQRDFDLLVLIPPSVLGAEAAQEVVGLAG 1989

Query: 308  NVARFTCTATGRPEPTMFWSVEG 330
              A   C   G P P + W+ +G
Sbjct: 1990 AGAELECRTLGVPTPQVEWTKDG 2012



 Score = 85.8 bits (203), Expect = 6e-15
 Identities = 75/257 (29%), Positives = 109/257 (42%), Gaps = 23/257 (8%)

Query: 227  GDPLPDVLWRRSAGGGNMPLGR---VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSA 283
            G P P V WR+  G  + PL     + VLD+GSL L +V  +D G+Y C+A N  G+ S 
Sbjct: 1813 GTPKPQVTWRK--GPSSEPLRDRPGLAVLDEGSLFLASVSPSDGGDYECQATNEAGSASR 1870

Query: 284  SGYLTVYDPPSINLSPNSVNVE--SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341
               L V+ PPS+       NV   +G      C A G P P + W ++  R I   G  R
Sbjct: 1871 RAKLVVHVPPSLREDGRRANVSGMAGQSLTLECDANGFPAPEITW-LKNGRQIPAVGSHR 1929

Query: 342  DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401
                   + DG   L      + DS     C A N AG++     L V      PP ++ 
Sbjct: 1930 -------LLDGARALHFPRIQEGDS-GLYSCRAENQAGTAQRDFDLLVLI----PPSVLG 1977

Query: 402  NGPSNQTLPIKSM-AVFPCTAICTPEPIIAWYFEGEALIQNHRR-NVTNDG-TLVLKDLD 458
               + + + +    A   C  +  P P + W  +G+ +     R  +  DG  L + +  
Sbjct: 1978 AEAAQEVVGLAGAGAELECRTLGVPTPQVEWTKDGQPVFLGEPRVQLQEDGQVLRITNSH 2037

Query: 459  KSDSGTYTCVASSRHGK 475
              D G Y CVA S  G+
Sbjct: 2038 LGDEGWYQCVAFSPAGQ 2054



 Score = 80.6 bits (190), Expect = 2e-13
 Identities = 62/179 (34%), Positives = 89/179 (49%), Gaps = 11/179 (6%)

Query: 27   QPATLNCRAGGSPSPAIRWYKGGVLVVS-DTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85
            Q  TL C A G P+P I W K G  + +  +HR +  A  L F R   G    D+G+Y C
Sbjct: 1897 QSLTLECDANGFPAPEITWLKNGRQIPAVGSHRLLDGARALHFPRIQEG----DSGLYSC 1952

Query: 86   EATNSYGTARSRNATLHVAVLREEFRLEPESKQ-SAQGDTVVLECLPPRGSPEPNVYWKK 144
             A N  GTA+ R+  L V +       E   +     G    LEC    G P P V W K
Sbjct: 1953 RAENQAGTAQ-RDFDLLVLIPPSVLGAEAAQEVVGLAGAGAELECRT-LGVPTPQVEWTK 2010

Query: 145  NGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKP 202
            +GQ  +F G+ R+ L + G ++ I ++   D G YQC+A + AG +++    L+IH +P
Sbjct: 2011 DGQP-VFLGEPRVQLQEDGQVLRITNSHLGDEGWYQCVAFSPAG-QQTKDFQLRIHGEP 2067



 Score = 51.6 bits (118), Expect = 1e-04
 Identities = 53/193 (27%), Positives = 82/193 (42%), Gaps = 22/193 (11%)

Query: 292  PPSI--NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
            PP+I  +   + V V  G+   F C A G P P + W  +G+  +     S +  +    
Sbjct: 2117 PPTIWGSNETSEVAVMEGHPVWFLCEARGVPTPDITWFKDGDPLV----PSTEVVYTR-- 2170

Query: 350  FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409
              G   L +     +D+  T  C A N  G      +L V      PP I   G   +  
Sbjct: 2171 --GGRQLQLERAQGSDA-GTYSCKASNAVGVVEKTTRLEVYV----PPTIEGTGEGPRV- 2222

Query: 410  PIKSMAVFPCTAICT----PEPIIAWYFEGEALIQNHRRNV-TNDGTLVLKDLDKSDSGT 464
             +K++A  P T  C     P P ++WY EG  ++  +   +    G L L+ L ++  G 
Sbjct: 2223 -VKAVAGRPLTLECVARGYPPPTVSWYHEGLPVVDRNGTWLGAGGGVLSLESLGEASGGL 2281

Query: 465  YTCVASSRHGKYV 477
            Y+CVASS  G+ V
Sbjct: 2282 YSCVASSPAGEAV 2294


>UniRef50_UPI0000F1ECB4 Cluster: PREDICTED: similar to hemicentin
           1,; n=1; Danio rerio|Rep: PREDICTED: similar to
           hemicentin 1, - Danio rerio
          Length = 413

 Score =  160 bits (388), Expect = 2e-37
 Identities = 126/429 (29%), Positives = 189/429 (44%), Gaps = 31/429 (7%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
           EAP ++  P   + +      ++C A GSP P + W  G +  +S+ HR  +   G+  +
Sbjct: 4   EAPSVVVSPQTQSFSLGAEVHISCSASGSPPPKVFWSHGNIF-LSNHHRMSISESGMLTI 62

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
           R   G    D+G Y C ATN  GTA S++  ++ A       +  +      G+   LEC
Sbjct: 63  R---GAAPEDSGNYTCLATNEVGTA-SQSVNVNYAE-PPSISVVQQMVMVVAGEDASLEC 117

Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
               G+P P V W+K G   L         V  G L I+  ++ D+G Y C+A N AG+ 
Sbjct: 118 -QASGTPSPIVKWQK-GDLDLGTAPFAEQDVHRGTLQIRGVQELDSGDYTCVASNIAGS- 174

Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG----GGNMP 245
            SA+  L++   P     P D+ A  G ++T  C   G P P ++WRR  G    G +  
Sbjct: 175 SSAVVVLQVGAAPTFSESPVDITASVGDNITLPCIARGFPTPSLIWRRQDGRPIFGKSSG 234

Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV--YDPPSINLSPNSVN 303
                 L  G+L++ +V + DEG Y CEA+N  G++ A   +TV   +PP +     S+ 
Sbjct: 235 HVGTSQLPSGALQIQSVWVDDEGVYLCEAKNQFGSIKALARVTVTGLEPPLLVQGAPSIT 294

Query: 304 VESGNVARFTC-TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
                     C    G P P   W+  G +        R         DG   L ++   
Sbjct: 295 TMIAQPLNLPCRLLDGIPLPERIWTHNGKQV-------RVGGRVFLRSDG--SLHVDRAV 345

Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
             D+  T VC+AVN AGS+     +TVT +   PP  I  GP + T    +     C A 
Sbjct: 346 PEDA-GTYVCTAVNVAGSA----NITVTVEVHAPPD-IKAGPLHYTASEGTPISLSCEAR 399

Query: 423 CTPEPIIAW 431
             P+P I+W
Sbjct: 400 GVPKPTISW 408



 Score =  134 bits (323), Expect = 2e-29
 Identities = 100/334 (29%), Positives = 147/334 (44%), Gaps = 26/334 (7%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV------LVVSDTHRS 59
           V   E P I      V V   + A+L C+A G+PSP ++W KG +          D HR 
Sbjct: 90  VNYAEPPSISVVQQMVMVVAGEDASLECQASGTPSPIVKWQKGDLDLGTAPFAEQDVHRG 149

Query: 60  ILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS 119
            L   G+  L         D+G Y C A+N  G++ S    L V      F   P    +
Sbjct: 150 TLQIRGVQEL---------DSGDYTCVASNIAGSS-SAVVVLQVGAA-PTFSESPVDITA 198

Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL----VDGGNLVIQDARQTDA 175
           + GD + L C+  RG P P++ W++     +F G S  H+    +  G L IQ     D 
Sbjct: 199 SVGDNITLPCIA-RGFPTPSLIWRRQDGRPIF-GKSSGHVGTSQLPSGALQIQSVWVDDE 256

Query: 176 GRYQCIARNAAGTRES-AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDV 233
           G Y C A+N  G+ ++ A  T+     P L+ G   +       +   CR+  G PLP+ 
Sbjct: 257 GVYLCEAKNQFGSIKALARVTVTGLEPPLLVQGAPSITTMIAQPLNLPCRLLDGIPLPER 316

Query: 234 LWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
           +W  +     +  GRV +  DGSL +D  +  D G Y C A N  G+ + +  + V+ PP
Sbjct: 317 IWTHNGKQVRVG-GRVFLRSDGSLHVDRAVPEDAGTYVCTAVNVAGSANITVTVEVHAPP 375

Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327
            I   P       G     +C A G P+PT+ WS
Sbjct: 376 DIKAGPLHYTASEGTPISLSCEARGVPKPTISWS 409



 Score =  131 bits (317), Expect = 1e-28
 Identities = 97/360 (26%), Positives = 152/360 (42%), Gaps = 15/360 (4%)

Query: 112 LEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR 171
           + P+++  + G  V + C    GSP P V+W      +      RM + + G L I+ A 
Sbjct: 10  VSPQTQSFSLGAEVHISC-SASGSPPPKVFWSHGN--IFLSNHHRMSISESGMLTIRGAA 66

Query: 172 QTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231
             D+G Y C+A N  GT   ++  +     P +    + V+   G   + +C+  G P P
Sbjct: 67  PEDSGNYTCLATNEVGTASQSV-NVNYAEPPSISVVQQMVMVVAGEDASLECQASGTPSP 125

Query: 232 DVLWRRS-AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290
            V W++     G  P     V   G+L++  V   D G+Y+C A N  G+ SA   L V 
Sbjct: 126 IVKWQKGDLDLGTAPFAEQDV-HRGTLQIRGVQELDSGDYTCVASNIAGSSSAVVVLQVG 184

Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
             P+ + SP  +    G+     C A G P P++ W  +  R I   G S      + + 
Sbjct: 185 AAPTFSESPVDITASVGDNITLPCIARGFPTPSLIWRRQDGRPIF--GKSSGHVGTSQLP 242

Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
            G   L I     +D     +C A N  GS     ++TVT  +   PP++  G  + T  
Sbjct: 243 SGA--LQIQSVWVDDE-GVYLCEAKNQFGSIKALARVTVTGLE---PPLLVQGAPSITTM 296

Query: 411 IKSMAVFPCTAIC-TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
           I      PC  +   P P   W   G+ +    R  + +DG+L +      D+GTY C A
Sbjct: 297 IAQPLNLPCRLLDGIPLPERIWTHNGKQVRVGGRVFLRSDGSLHVDRAVPEDAGTYVCTA 356



 Score = 93.9 bits (223), Expect = 2e-17
 Identities = 70/235 (29%), Positives = 104/235 (44%), Gaps = 14/235 (5%)

Query: 9   GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG---VLVVSDTH--RSILPA 63
           G AP   E P+D+T +     TL C A G P+P++ W +     +   S  H   S LP+
Sbjct: 184 GAAPTFSESPVDITASVGDNITLPCIARGFPTPSLIWRRQDGRPIFGKSSGHVGTSQLPS 243

Query: 64  GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQG 122
           G L            D GVY CEA N +G+ ++  A + V  L     ++   S  +   
Sbjct: 244 GALQIQSVWV----DDEGVYLCEAKNQFGSIKAL-ARVTVTGLEPPLLVQGAPSITTMIA 298

Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
             + L C    G P P   W  NG+ +   G  R+ L   G+L +  A   DAG Y C A
Sbjct: 299 QPLNLPCRLLDGIPLPERIWTHNGKQVRVGG--RVFLRSDGSLHVDRAVPEDAGTYVCTA 356

Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
            N AG+    + T+++H  P +  GP    A  G+ ++  C   G P P + W +
Sbjct: 357 VNVAGSANITV-TVEVHAPPDIKAGPLHYTASEGTPISLSCEARGVPKPTISWSK 410



 Score = 89.8 bits (213), Expect = 4e-16
 Identities = 75/281 (26%), Positives = 107/281 (38%), Gaps = 26/281 (9%)

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---RVKVLDDGSLR 258
           P ++  P+      G+ V   C   G P P V W      GN+ L    R+ + + G L 
Sbjct: 6   PSVVVSPQTQSFSLGAEVHISCSASGSPPPKVFWSH----GNIFLSNHHRMSISESGMLT 61

Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATG 318
           +      D G Y+C A N VG  S S  +   +PPSI++    V V +G  A   C A+G
Sbjct: 62  IRGAAPEDSGNYTCLATNEVGTASQSVNVNYAEPPSISVVQQMVMVVAGEDASLECQASG 121

Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
            P P + W          P   +D +  T    GV  L   D           C A N A
Sbjct: 122 TPSPIVKWQKGDLDLGTAPFAEQDVHRGTLQIRGVQELDSGD---------YTCVASNIA 172

Query: 379 GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-YFEGEA 437
           GSS     L V +      P  +  P + T  +      PC A   P P + W   +G  
Sbjct: 173 GSSSAVVVLQVGA-----APTFSESPVDITASVGDNITLPCIARGFPTPSLIWRRQDGRP 227

Query: 438 LIQNHRRNVTN----DGTLVLKDLDKSDSGTYTCVASSRHG 474
           +      +V       G L ++ +   D G Y C A ++ G
Sbjct: 228 IFGKSSGHVGTSQLPSGALQIQSVWVDDEGVYLCEAKNQFG 268



 Score = 61.7 bits (143), Expect = 1e-07
 Identities = 53/186 (28%), Positives = 82/186 (44%), Gaps = 18/186 (9%)

Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
           + PS+ +SP + +   G     +C+A+G P P +FWS  GN   IF       +H  ++ 
Sbjct: 4   EAPSVVVSPQTQSFSLGAEVHISCSASGSPPPKVFWS-HGN---IF----LSNHHRMSIS 55

Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
           +   +LTI      DS N   C A N  G++     +         PP I+       + 
Sbjct: 56  ES-GMLTIRGAAPEDSGN-YTCLATNEVGTASQSVNVNYAE-----PPSISVVQQMVMVV 108

Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQN--HRRNVTNDGTLVLKDLDKSDSGTYTCV 468
               A   C A  TP PI+ W  +G+  +          + GTL ++ + + DSG YTCV
Sbjct: 109 AGEDASLECQASGTPSPIVKWQ-KGDLDLGTAPFAEQDVHRGTLQIRGVQELDSGDYTCV 167

Query: 469 ASSRHG 474
           AS+  G
Sbjct: 168 ASNIAG 173


>UniRef50_Q9VS29 Cluster: CG32387-PA, isoform A; n=15;
            Endopterygota|Rep: CG32387-PA, isoform A - Drosophila
            melanogaster (Fruit fly)
          Length = 1770

 Score =  160 bits (388), Expect = 2e-37
 Identities = 200/847 (23%), Positives = 346/847 (40%), Gaps = 89/847 (10%)

Query: 9    GEAPYIIEQPLDVTVARHQPA-TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI---LPAG 64
            G+AP ++         +  PA +L C A G+P+P I W   G  + S+    I   +   
Sbjct: 385  GDAPPVLLYSFIEQTLQPGPAVSLKCSAAGNPTPQISWTLDGFPLPSNGRFMIGQYITVH 444

Query: 65   G--LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122
            G  +  +  +H  V  D G Y C A N  G  +   A L++  L    RL P+   +  G
Sbjct: 445  GDVISHVNISHVMVE-DGGEYACIAENRAGRVQHA-ARLNIYGL-PYIRLIPKVT-AVSG 500

Query: 123  DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ-TDAGRYQCI 181
            +T+ L+C P  G P   ++W++ G+ L    D R  +   G+L I   ++ +D+G Y C 
Sbjct: 501  ETLNLKC-PVAGYPIEEIHWERGGREL--PDDIRQRVQPDGSLTISPVQKNSDSGVYTCW 557

Query: 182  ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAG 240
            ARN  G        + + + P +           G      C V  GDP   ++W +   
Sbjct: 558  ARNKQGHSARRSGEVTVIVPPSIEPFAFQEGLAEGMRTRTVCGVSRGDPPLKLIWLKD-- 615

Query: 241  GGNMP--LG-RVKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295
            G  +P  LG  V +LD  S  L + ++     GEY+C A+N    +  +  L V  PP  
Sbjct: 616  GDPLPDLLGANVTMLDQYSSLLSIPSLSATHSGEYTCVAKNPAAEIKYTALLQVKVPPRW 675

Query: 296  NLSPNSVNVESGNVARFTCTATGRPEPTMFW-SVEGNRTIIFPGMSRDKYHATAVFDGVT 354
             + P   NVE        C A G P P++ W    G+++  +  + R++     + +G  
Sbjct: 676  IVEPVDANVERNRHIMLHCQAQGVPTPSIVWKKATGSKSGEYEEV-RERPFTKLLGNGSL 734

Query: 355  VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
            +L      K D     +C A N  G+    GK+     +  P     +  S   +  K  
Sbjct: 735  LL---QHVKEDREGFYLCQANNGIGTGI--GKVIQLKVNSSP---YFSSTSRSVMVKKGD 786

Query: 415  AVFPCTAICTPEPI-IAWYFEGEALIQ---NHRRNVTNDGT-------LVLKDLDKSDSG 463
                  A+   +PI I W   G+  +    N++ +V  + T       L ++ +D +DSG
Sbjct: 787  TALLQCAVSGDKPINIVWMRSGKNTLNPSTNYKISVKQEATPDGVSAELQIRTVDATDSG 846

Query: 464  TYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLS 523
             Y C AS+ +G       L V  P                P PP+      ++  SV + 
Sbjct: 847  PYFCRASNLYGNDQQLVQLQVQEP----------------PLPPSVLEAAMISSRSVNIK 890

Query: 524  WSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITY 583
            W Q   +G+  +  Y VE    + L  +   +      +  +     + ++++L P   Y
Sbjct: 891  W-QPKTLGTGDVTKYIVEFREADPLFVDQWQQ------IEVKDPPHFNAMIENLKPATRY 943

Query: 584  MFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATP 643
             F V  E S G S P   S  + V  +        G   S   R    T+ ++  +   P
Sbjct: 944  AFRVIAEGSAGRSAP---SQELIVRTEPQ---RPAGPPLSLSARPLSSTELLISWVAPLP 997

Query: 644  IDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFE--ITSLRKYT 701
                        L    ++G  + ++   +    Y   ++    D    E  ++ L K+ 
Sbjct: 998  -----------ELRHGDIQGYNVGYKLSSSGNTAYNFTSVSGDGDGGNGELLLSGLAKFA 1046

Query: 702  KYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQN 761
            +Y   +  F +   G  S    AQT++DVP  PP ++    L++ ++ + W PP +   N
Sbjct: 1047 RYTVVVQAFNQVGPGPLSEPTAAQTMEDVPSRPPEDVRCAALSSQSLQVSWQPPPIYHTN 1106

Query: 762  GIITGYNVVVNWL--DVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819
            G++ GY ++   +  D+  +K  V    T   A ++++T L    +YS+Q+ A T +G G
Sbjct: 1107 GLLQGYKLIFEPIIDDIQPSKDEVESRKTT--ALTMVLTGLRKYTNYSIQVLAHTRMGDG 1164

Query: 820  PFSQKVY 826
              S+ ++
Sbjct: 1165 VVSKPLF 1171



 Score =  137 bits (331), Expect = 2e-30
 Identities = 126/490 (25%), Positives = 206/490 (42%), Gaps = 45/490 (9%)

Query: 15  IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTH--RSILPAGGLFFLRAT 72
           +E P  V  +      L+C A GSP P + W       V++ H  R +L  G L  +   
Sbjct: 1   MEPPGRVEFSNSSGGWLDCSASGSPQPTVDWVHADGSAVTEIHGVRRVLRNGTLVLMPFA 60

Query: 73  HGRVHSDAG--VYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
               H D    +Y C A+NS G   SR+  +  AV+ + ++++ E   +A+G T +L C+
Sbjct: 61  AAAYHQDVHNTIYRCIASNSVGRIVSRDVQVR-AVVAQAYKVDVEVLSAARGCTAILRCV 119

Query: 131 PPRGSPE--PNVYWKKNGQTLLF---DGDSRMHLVDGGNLVIQDARQTDAGR-YQCIARN 184
            P    E    V W       ++    GD + HL+  G L+I + +++D  + ++C + +
Sbjct: 120 VPTFVKELVRVVSWVHEPAIYIYPSLQGDGKFHLLPTGELLIHNLQESDESQSFRCRSMH 179

Query: 185 AAGTRESAIAT---LKIH-----IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
              TR+  +++   L+I+     I P ++     V           C   G P P+  W 
Sbjct: 180 RL-TRQVVVSSPTRLRINSHRGIISPSVVEHTAHVQVSQDEGAVLLCVAQGCPSPEYSWF 238

Query: 237 RSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
              G G +P+    RV++L    L ++ V   D G Y C A N  G  SA   LTV  P 
Sbjct: 239 THNGAGPLPVLSGPRVRLLGP-ILAIEAVTGEDSGVYKCTAGNVGGEASAELRLTVATPI 297

Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
            + +SPN ++V  G  A F C  T    P       G + I++    R    +  V D +
Sbjct: 298 QVEISPNVLSVHMGGTAEFRCLVTSNGSPV------GMQNILWYKDGRQLPSSGRVEDTL 351

Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413
            V  ++     ++R    C      G +F   + T        PP++      QTL    
Sbjct: 352 VVPRVS----RENRGMYQCVVRRPEGDTF---QATAELQLGDAPPVLLYSFIEQTLQPGP 404

Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHR----RNVTNDGTLV----LKDLDKSDSGTY 465
                C+A   P P I+W  +G  L  N R    + +T  G ++    +  +   D G Y
Sbjct: 405 AVSLKCSAAGNPTPQISWTLDGFPLPSNGRFMIGQYITVHGDVISHVNISHVMVEDGGEY 464

Query: 466 TCVASSRHGK 475
            C+A +R G+
Sbjct: 465 ACIAENRAGR 474



 Score =  133 bits (322), Expect = 2e-29
 Identities = 142/497 (28%), Positives = 199/497 (40%), Gaps = 47/497 (9%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK---GGVLVVSDTHRSILPAGGLF 67
           +P ++E    V V++ + A L C A G PSP   W+     G L V    R  L  G + 
Sbjct: 203 SPSVVEHTAHVQVSQDEGAVLLCVAQGCPSPEYSWFTHNGAGPLPVLSGPRVRL-LGPIL 261

Query: 68  FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
            + A  G    D+GVY C A N  G A S    L VA    +  + P       G T   
Sbjct: 262 AIEAVTG---EDSGVYKCTAGNVGGEA-SAELRLTVAT-PIQVEISPNVLSVHMGGTAEF 316

Query: 128 ECL-PPRGSP--EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
            CL    GSP    N+ W K+G+ L   G  R+       LV+    + + G YQC+ R 
Sbjct: 317 RCLVTSNGSPVGMQNILWYKDGRQLPSSG--RVE----DTLVVPRVSRENRGMYQCVVRR 370

Query: 185 AAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA---- 239
             G    A A L++    P L+    +   Q G +V+ +C   G+P P + W        
Sbjct: 371 PEGDTFQATAELQLGDAPPVLLYSFIEQTLQPGPAVSLKCSAAGNPTPQISWTLDGFPLP 430

Query: 240 GGGNMPLGR-VKVLDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
             G   +G+ + V  D    + + +V++ D GEY+C AEN  G V  +  L +Y  P I 
Sbjct: 431 SNGRFMIGQYITVHGDVISHVNISHVMVEDGGEYACIAENRAGRVQHAARLNIYGLPYIR 490

Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
           L P  V   SG      C   G P   + W   G R +  P   R +       DG   L
Sbjct: 491 LIP-KVTAVSGETLNLKCPVAGYPIEEIHWE-RGGREL--PDDIRQRVQP----DG--SL 540

Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVR-GKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
           TI+   KN       C A N  G S  R G++TV       PP I      + L      
Sbjct: 541 TISPVQKNSDSGVYTCWARNKQGHSARRSGEVTVI-----VPPSIEPFAFQEGLAEGMRT 595

Query: 416 VFPCTAICTPEPI-IAWYFEGEALIQNHRRNVT----NDGTLVLKDLDKSDSGTYTCVAS 470
              C       P+ + W  +G+ L      NVT        L +  L  + SG YTCVA 
Sbjct: 596 RTVCGVSRGDPPLKLIWLKDGDPLPDLLGANVTMLDQYSSLLSIPSLSATHSGEYTCVAK 655

Query: 471 SRHGKYVWSGALLVDSP 487
           +   +  ++  L V  P
Sbjct: 656 NPAAEIKYTALLQVKVP 672



 Score = 48.4 bits (110), Expect = 0.001
 Identities = 45/211 (21%), Positives = 90/211 (42%), Gaps = 15/211 (7%)

Query: 637  ELIEATPIDSKTIKLMWEILNFYYLEGLF----IYFRPLDNITIEYEMKTILHSNDVSGF 692
            E +    + S+++++ W+    Y+  GL     + F P+ +     + +           
Sbjct: 1081 EDVRCAALSSQSLQVSWQPPPIYHTNGLLQGYKLIFEPIIDDIQPSKDEVESRKTTALTM 1140

Query: 693  EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKW 752
             +T LRKYT Y   ++   +  +G  S      + +DVP+  P +I++   ++ ++++ W
Sbjct: 1141 VLTGLRKYTNYSIQVLAHTRMGDGVVSKPLFCHSEEDVPEA-PADIKVVSSSSQSLYISW 1199

Query: 753  SPPELQLQNGIITGYNV---VVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQ 809
             PP     NG+IT Y++   VVN  +   N+      +   Q        L   + Y   
Sbjct: 1200 LPP--NEPNGVITKYSLYTRVVNGREELNNEK----RSLPSQQAYYEAKGLHPHMEYQFW 1253

Query: 810  IAAETIIGLGPFSQKVYFNIDSRSVGLDLLS 840
            + A T +G G  S +V   I +  +   ++S
Sbjct: 1254 VTASTRVGEGK-SSRVSSQITTNRIPARIIS 1283



 Score = 46.8 bits (106), Expect = 0.004
 Identities = 38/129 (29%), Positives = 57/129 (44%), Gaps = 5/129 (3%)

Query: 191  SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP-LGRV 249
            S I T +I  +     GP  VV    S+VT  C   G P  +  W +S        L   
Sbjct: 1270 SQITTNRIPARIISFGGP--VVRPWRSTVTLPCTAVGKPKRE--WFKSDVALRQGGLHNS 1325

Query: 250  KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309
            ++LD G L + ++ LAD G YSC+ +N +G    +  L V  PP+  +   +    S  +
Sbjct: 1326 QLLDSGDLIISSLQLADGGNYSCQVDNGIGTDRLTHTLIVQVPPTAPVLYVTSATSSSIL 1385

Query: 310  ARFTCTATG 318
              + C  TG
Sbjct: 1386 MHWKCGFTG 1394



 Score = 45.2 bits (102), Expect = 0.011
 Identities = 80/343 (23%), Positives = 125/343 (36%), Gaps = 28/343 (8%)

Query: 83   YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG--DTVVLECLPPRGSPEPNV 140
            +W  A+   G  +S   +  +   R   R+        +    TV L C    G P+   
Sbjct: 1252 FWVTASTRVGEGKSSRVSSQITTNRIPARIISFGGPVVRPWRSTVTLPCTAV-GKPKRE- 1309

Query: 141  YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
             W K+   L   G     L+D G+L+I   +  D G Y C   N  GT +    TL + +
Sbjct: 1310 -WFKSDVALRQGGLHNSQLLDSGDLIISSLQLADGGNYSCQVDNGIGT-DRLTHTLIVQV 1367

Query: 201  KPYLITGPE-DVVAQTGSSVTFQCR---VGGDPLP--DVLWRRSAGG-GNMPLGRVKVLD 253
             P   T P   V + T SS+    +    G  P+    + +RR+ G    M L R     
Sbjct: 1368 PP---TAPVLYVTSATSSSILMHWKCGFTGNAPITGYTLFYRRANGNTDEMQLSR----H 1420

Query: 254  DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313
              S  L  ++     +    A+N VG    S  L V         P S  + + N     
Sbjct: 1421 ASSHELKGLMCGSTYQIHLSAQNKVGTSPTSTILHVRTQGQSPGHPASTALLAPNSTSLL 1480

Query: 314  CTATGRPE---PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
                  P+   P +++ ++       P    +    +        + IN+   + +   +
Sbjct: 1481 VRLHSWPDNGCPLLYFVLQYRAVTDDP--DAEWVLVSNALKPQRRIVINNLQPS-TLYQL 1537

Query: 371  VCSAVNYAGSSFVR-GKLTVTSDDDRPPP-IITNGPSNQTLPI 411
               A N AG S      +T+T D D PPP I+  G S QT  I
Sbjct: 1538 RMEAHNVAGISQAEFNFVTLTKDGDPPPPEIMHRGRSGQTTVI 1580



 Score = 44.4 bits (100), Expect = 0.019
 Identities = 32/121 (26%), Positives = 51/121 (42%), Gaps = 4/121 (3%)

Query: 410  PIKSMAVFPCTAICTPEPIIAWYFEGEALIQN--HRRNVTNDGTLVLKDLDKSDSGTYTC 467
            P +S    PCTA+  P+    W+    AL Q   H   + + G L++  L  +D G Y+C
Sbjct: 1291 PWRSTVTLPCTAVGKPKR--EWFKSDVALRQGGLHNSQLLDSGDLIISSLQLADGGNYSC 1348

Query: 468  VASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527
               +  G    +  L+V  P    + +  +A  SS+        T N   T  TL + + 
Sbjct: 1349 QVDNGIGTDRLTHTLIVQVPPTAPVLYVTSATSSSILMHWKCGFTGNAPITGYTLFYRRA 1408

Query: 528  N 528
            N
Sbjct: 1409 N 1409



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 67/304 (22%), Positives = 108/304 (35%), Gaps = 25/304 (8%)

Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK-VLDDGSLRLDNVILAD 266
           P  V     S     C   G P P V W  + G     +  V+ VL +G+L L     A 
Sbjct: 4   PGRVEFSNSSGGWLDCSASGSPQPTVDWVHADGSAVTEIHGVRRVLRNGTLVLMPFAAAA 63

Query: 267 EGE------YSCEAENSVGA-VSASGYLTVYDPPSINLSPNSVNVESGNVARFTC---TA 316
             +      Y C A NSVG  VS    +      +  +    ++   G  A   C   T 
Sbjct: 64  YHQDVHNTIYRCIASNSVGRIVSRDVQVRAVVAQAYKVDVEVLSAARGCTAILRCVVPTF 123

Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRD-KYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
                  + W V      I+P +  D K+H     +    L I++  ++D   +  C ++
Sbjct: 124 VKELVRVVSW-VHEPAIYIYPSLQGDGKFHLLPTGE----LLIHNLQESDESQSFRCRSM 178

Query: 376 NYAGSSFVRG---KLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
           +      V     +L + S      P +    ++  +     AV  C A   P P  +W+
Sbjct: 179 HRLTRQVVVSSPTRLRINSHRGIISPSVVEHTAHVQVSQDEGAVLLCVAQGCPSPEYSWF 238

Query: 433 FEGEA----LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPI 488
               A    ++   R  +     L ++ +   DSG Y C A +  G+      L V +PI
Sbjct: 239 THNGAGPLPVLSGPRVRLLGP-ILAIEAVTGEDSGVYKCTAGNVGGEASAELRLTVATPI 297

Query: 489 NPNI 492
              I
Sbjct: 298 QVEI 301


>UniRef50_UPI000065D4F5 Cluster: Homolog of Danio rerio "Novel
            hemicentin protein; n=1; Takifugu rubripes|Rep: Homolog
            of Danio rerio "Novel hemicentin protein - Takifugu
            rubripes
          Length = 2555

 Score =  159 bits (386), Expect = 4e-37
 Identities = 143/486 (29%), Positives = 220/486 (45%), Gaps = 49/486 (10%)

Query: 4    DY-VTSGEAPYII--EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDT-HR 58
            DY +T   +P I+  E P +V+    +  TL CRA G+P+P + W K GV V  SD+ H 
Sbjct: 1418 DYALTVQVSPTILDSEHPSEVSAPMGEDMTLECRAAGNPTPHLSWLKDGVTVEGSDSRHI 1477

Query: 59   SILPAGG-LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEP 114
             + P G  L  LR +      D+G Y C A +  G  +++  TL V V   +  E  + P
Sbjct: 1478 GVTPEGSTLTLLRLS----PDDSGTYTCLAVSPAG-RQTKIYTLFVLVPPSISGETTV-P 1531

Query: 115  ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTD 174
               Q  Q   V LEC    GSP P + W KNG  LL    +R+   D   L I   + +D
Sbjct: 1532 REVQVTQDGAVTLEC-QAVGSPPPQISWLKNGHPLLLSSRTRLLSAD-SVLRISPVQLSD 1589

Query: 175  AGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL 234
            +G Y C+AR+ AG  E +   +++ ++P  I          GS VT  C   G P P + 
Sbjct: 1590 SGVYTCMARSQAGLAELSY-DVQVQVEPVTIV--------QGSLVTLSCEARGVPPPTLT 1640

Query: 235  WRRSAGGGNMPLGRVKVLD--DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
            W +   G  + L R  +LD  +  L+L +V  +D G YSC A N  G+ + +  LTV +P
Sbjct: 1641 WLKD--GQPLSLHRNLLLDGQETRLQLPDVGPSDAGLYSCVASNQAGSSTKTFNLTVLEP 1698

Query: 293  PSI--NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
            P +  + SP  + +   +     C+ATG P PT+ W  +G+     P   RD       F
Sbjct: 1699 PKMTGSSSPEELFIAVNSPLELECSATGVPPPTLTWLKDGH-----PLERRDIVQEDGHF 1753

Query: 351  DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTL 409
              ++ + + D           C A + AG       + V      PP ++ ++     T+
Sbjct: 1754 VRISKVQVEDA------GLYTCLASSLAGEDGKNHWIRV----QVPPTLLGSDEVRTVTV 1803

Query: 410  PIKSMAVFPCTAICTPEPIIAWY-FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468
            P+       C A   P P I WY  E +  +    + +     L ++++   DSG Y+CV
Sbjct: 1804 PVNGHLTLECLADSDPAPDIEWYKDEVKVQLGGRVQQLAGGQYLEIQEVKPEDSGLYSCV 1863

Query: 469  ASSRHG 474
             ++  G
Sbjct: 1864 VTNMAG 1869



 Score =  156 bits (379), Expect = 3e-36
 Identities = 137/470 (29%), Positives = 209/470 (44%), Gaps = 46/470 (9%)

Query: 17   QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV 76
            + L+ T+  H   +L C+A G P P+I W K G  + S         G    L       
Sbjct: 1343 ESLNYTLGSH--VSLPCQASGFPVPSITWLKDGTPIESSLQWQWSIRGSRLELGPL---A 1397

Query: 77   HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLECLPPRGS 135
             +  G+Y C A NS G A+ ++  L V V       E  S+ SA  G+ + LEC    G+
Sbjct: 1398 LAHGGLYTCLAKNSEGQAQ-KDYALTVQVSPTILDSEHPSEVSAPMGEDMTLECRAA-GN 1455

Query: 136  PEPNVYWKKNGQTLLFDGDSRMHL---VDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
            P P++ W K+G T+  +G    H+    +G  L +      D+G Y C+A + AG R++ 
Sbjct: 1456 PTPHLSWLKDGVTV--EGSDSRHIGVTPEGSTLTLLRLSPDDSGTYTCLAVSPAG-RQTK 1512

Query: 193  IATLKIHIKPYL---ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249
            I TL + + P +    T P +V      +VT +C+  G P P + W ++ G   +   R 
Sbjct: 1513 IYTLFVLVPPSISGETTVPREVQVTQDGAVTLECQAVGSPPPQISWLKN-GHPLLLSSRT 1571

Query: 250  KVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGN 308
            ++L  D  LR+  V L+D G Y+C A +  G    S     YD   + +    V +  G+
Sbjct: 1572 RLLSADSVLRISPVQLSDSGVYTCMARSQAGLAELS-----YD---VQVQVEPVTIVQGS 1623

Query: 309  VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV-TVLTINDTDKNDSR 367
            +   +C A G P PT+ W  +G    +         H   + DG  T L + D   +D+ 
Sbjct: 1624 LVTLSCEARGVPPPTLTWLKDGQPLSL---------HRNLLLDGQETRLQLPDVGPSDA- 1673

Query: 368  NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIKSMAVFPCTAICTPE 426
                C A N AGSS     LTV      PP +  ++ P    + + S     C+A   P 
Sbjct: 1674 GLYSCVASNQAGSSTKTFNLTVLE----PPKMTGSSSPEELFIAVNSPLELECSATGVPP 1729

Query: 427  PIIAWYFEGEALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHGK 475
            P + W  +G  L    R  V  DG  V +  +   D+G YTC+ASS  G+
Sbjct: 1730 PTLTWLKDGHPL--ERRDIVQEDGHFVRISKVQVEDAGLYTCLASSLAGE 1777



 Score =  148 bits (358), Expect = 1e-33
 Identities = 137/494 (27%), Positives = 210/494 (42%), Gaps = 59/494 (11%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS--DTHRSILPAGGLFFL 69
            P I +    VT  +  PA L C   G P P + W KGG  + S   T+R +LP G    L
Sbjct: 2079 PSIEDDVTAVTAVKLAPAVLPCHVHGRPQPTVFWTKGGAKLSSRGGTYR-VLPTG---LL 2134

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
              T   + S AG Y C A NS G A  ++ +L V     E R   E  Q       VL C
Sbjct: 2135 EIT-SVLPSHAGRYTCSARNSAGVAH-KHVSLSVQE-SPEIRPMAEEVQVVLHHGTVLPC 2191

Query: 130  LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
               +G P P++ W++ G  +      R+ L+  G L        DAG YQC+A+N AG  
Sbjct: 2192 -EAQGFPRPSISWQREGVPIATG--HRLSLLSNGALKFSRVTLGDAGTYQCLAKNEAGAA 2248

Query: 190  ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGR 248
                  L +H+ P +     ++    G      C   G P P + W ++     N+P G+
Sbjct: 2249 VGQ-TKLVLHVPPLISPAQTELSVIQGFQALLSCAAQGSPDPKISWEKNGSPVPNIP-GK 2306

Query: 249  VKVLDDGSLRLDN-----VILA---------------------DEGEYSCEAENSVGAVS 282
              VL  G L ++      +ILA                     D G ++C A N+ G+  
Sbjct: 2307 YTVLRSGELIIERAEVCLLILAALRLEAHQNPLNQFWFLTQPADAGLFTCVATNAAGSAR 2366

Query: 283  ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRD 342
                L++   P+    P  V +  G     +C A G P P + W+V  +      G + D
Sbjct: 2367 QDRRLSINMRPAFKELPGDVTLNKGQSLALSCHAQGTPSPVISWTVNNSPR---QGAAVD 2423

Query: 343  KYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT- 401
            +        G + L I +   +D+  T VC A N  GS  VR   T++    R PP++  
Sbjct: 2424 E-------AGRSSLIIENVTTSDA-GTYVCVAENRVGS--VR---TLSFVRVREPPVLKG 2470

Query: 402  NGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLD-KS 460
            +   +QT+   S  +  C     P P++ W  +G AL+++HR     +G+LV+  ++  +
Sbjct: 2471 DAHMSQTVIQGSSTILDCPIHGDPSPVLQWLRDGNALLRSHRIQALLNGSLVIYSVNVNT 2530

Query: 461  DSGTYTCVASSRHG 474
              G Y C+A +  G
Sbjct: 2531 HEGEYQCLAENEAG 2544



 Score =  147 bits (356), Expect = 2e-33
 Identities = 132/496 (26%), Positives = 197/496 (39%), Gaps = 49/496 (9%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRS--ILPAGGLFF 68
            P I   P +VTV     A L+C   G PSP + W + G  L VS    +  +L +G L  
Sbjct: 1973 PSISPGPFNVTVTSGIRAVLSCETTGIPSPKVSWKRNGTPLDVSQLSGAFRLLSSGSLVL 2032

Query: 69   LRATHGRVHSDAGVYWCEATNSYGTARS------RNATLHVAVLREEFRLEPESKQSAQG 122
            L  ++     D G + C A N  G  R       ++    V V    F   P S +    
Sbjct: 2033 LSPSN----EDEGYFECTAVNEAGEERRVIEVILQDGQTDVCVFM--FCSVPPSIEDDVT 2086

Query: 123  DTVVLECLPP------RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAG 176
                ++  P        G P+P V+W K G  L   G +   ++  G L I     + AG
Sbjct: 2087 AVTAVKLAPAVLPCHVHGRPQPTVFWTKGGAKLSSRGGT-YRVLPTGLLEITSVLPSHAG 2145

Query: 177  RYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
            RY C ARN+AG     ++ L +   P +    E+V           C   G P P + W+
Sbjct: 2146 RYTCSARNSAGVAHKHVS-LSVQESPEIRPMAEEVQVVLHHGTVLPCEAQGFPRPSISWQ 2204

Query: 237  RSAGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295
            R   G  +  G R+ +L +G+L+   V L D G Y C A+N  GA      L ++ PP I
Sbjct: 2205 RE--GVPIATGHRLSLLSNGALKFSRVTLGDAGTYQCLAKNEAGAAVGQTKLVLHVPPLI 2262

Query: 296  NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
            + +   ++V  G  A  +C A G P+P + W   G+     PG          + +   V
Sbjct: 2263 SPAQTELSVIQGFQALLSCAAQGSPDPKISWEKNGSPVPNIPGKYTVLRSGELIIERAEV 2322

Query: 356  ---------LTINDTDKND--------SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398
                     L  +    N               C A N AGS+    +L++        P
Sbjct: 2323 CLLILAALRLEAHQNPLNQFWFLTQPADAGLFTCVATNAAGSARQDRRLSINM-----RP 2377

Query: 399  IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLD 458
                 P + TL         C A  TP P+I+W        Q    +     +L+++++ 
Sbjct: 2378 AFKELPGDVTLNKGQSLALSCHAQGTPSPVISWTVNNSPR-QGAAVDEAGRSSLIIENVT 2436

Query: 459  KSDSGTYTCVASSRHG 474
             SD+GTY CVA +R G
Sbjct: 2437 TSDAGTYVCVAENRVG 2452



 Score =  146 bits (353), Expect = 4e-33
 Identities = 135/483 (27%), Positives = 198/483 (40%), Gaps = 40/483 (8%)

Query: 21   VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
            VTV  +   TL C A   P+P I WYK  V V        L  G    ++        D+
Sbjct: 1801 VTVPVNGHLTLECLADSDPAPDIEWYKDEVKVQLGGRVQQLAGGQYLEIQEVKPE---DS 1857

Query: 81   GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDTVVLECLPPRGSPEPN 139
            G+Y C  TN  G   S +    V +L      E  S+ +   G   +L C     S    
Sbjct: 1858 GLYSCVVTNMAG---SSSLFFTVEILLPPIIRESSSEVTTHIGQDALLPCEVEEES-HAT 1913

Query: 140  VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
            V W+K+G  +    D+R  L+  G+L I   + +DAGRY C   N AG+    +  L++ 
Sbjct: 1914 VTWRKDGFPIT--QDNRYTLLSEGSLRIHGVQLSDAGRYYCTVSNQAGSDHRGVE-LRVF 1970

Query: 200  IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL--GRVKVLDDGSL 257
            + P +  GP +V   +G      C   G P P V W+R+    ++    G  ++L  GSL
Sbjct: 1971 VGPSISPGPFNVTVTSGIRAVLSCETTGIPSPKVSWKRNGTPLDVSQLSGAFRLLSSGSL 2030

Query: 258  RLDNVILADEGEYSCEAENSVG-------AVSASG------YLTVYDPPSINLSPNSVNV 304
             L +    DEG + C A N  G        +   G      ++    PPSI     +V  
Sbjct: 2031 VLLSPSNEDEGYFECTAVNEAGEERRVIEVILQDGQTDVCVFMFCSVPPSIEDDVTAVTA 2090

Query: 305  ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
                 A   C   GRP+PT+FW+  G +     G  R     T + +  +VL       +
Sbjct: 2091 VKLAPAVLPCHVHGRPQPTVFWTKGGAKLSSRGGTYR--VLPTGLLEITSVLP-----SH 2143

Query: 365  DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
              R T  CSA N AG +     L+V        P I        + +    V PC A   
Sbjct: 2144 AGRYT--CSARNSAGVAHKHVSLSVQES-----PEIRPMAEEVQVVLHHGTVLPCEAQGF 2196

Query: 425  PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
            P P I+W  EG  +   HR ++ ++G L    +   D+GTY C+A +  G  V    L++
Sbjct: 2197 PRPSISWQREGVPIATGHRLSLLSNGALKFSRVTLGDAGTYQCLAKNEAGAAVGQTKLVL 2256

Query: 485  DSP 487
              P
Sbjct: 2257 HVP 2259



 Score =  136 bits (329), Expect = 3e-30
 Identities = 110/392 (28%), Positives = 161/392 (41%), Gaps = 15/392 (3%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
           EAP ++  P     +R +     C A GSP P + W  G +L+ +    +I   G L   
Sbjct: 82  EAPSVVIHPQSRVFSRGEEIRFVCSASGSPPPQLFWSHGNMLLTNRQRLNINHYGVL--- 138

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
               G +  DAG Y C ATN  G A S++ +L  +      R+  ++   + G   VLEC
Sbjct: 139 -TIKGALPEDAGNYTCLATNEAGVA-SQSVSLTFSEA-PRIRVTQQAIHVSVGADAVLEC 195

Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
               G+P P V W K G+  +         V  G+L I+  ++ DAGRY C+A + AGT 
Sbjct: 196 -QATGAPPPLVRWFK-GEFEVGSTPFAGQDVHHGDLHIRGVQEVDAGRYTCVASSPAGTA 253

Query: 190 ESAIATLKIHIKPYLI--TGPEDVV---AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
              +  LK+   P +I  T  +  V    + G+ V   C   G+P P V W R+      
Sbjct: 254 TGTVI-LKVGAMPKIIGVTSNDKTVKMAVEVGTEVVLPCEAQGNPSPLVTWSRNGHPIPP 312

Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
                 VL  GSLR+ +V L D   Y+C AEN  G VS S  L +   P I  +   +  
Sbjct: 313 VTAGFTVLPSGSLRITDVRLIDSKRYTCTAENPAGNVSLSYNLHIQAKPRIQPAATLLKA 372

Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
             G      C   G P P + W   G   +     +  + H   + D  T   +      
Sbjct: 373 RIGQTVTLPCVVQGEPSPEVTWFHNG-LPVGIKNATPLRIHQAKLGDQGTYRCVATNSAG 431

Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP 396
              + I    +    S+F    + V S   RP
Sbjct: 432 QETSEIKLDILVRRNSAFAHSFVFVNSGSPRP 463



 Score =  134 bits (325), Expect = 1e-29
 Identities = 135/505 (26%), Positives = 208/505 (41%), Gaps = 49/505 (9%)

Query: 17   QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV 76
            + LDV +    P +L+C +   P P + W+K G  ++S     +LP G +  +       
Sbjct: 945  EKLDVVLGH--PVSLSCESNAIPPPKLSWHKDGQKLLSGDGVVLLPGGQVLQIARVR--- 999

Query: 77   HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
              DAG Y C+A N  G     +  LH+    E+F    E   +    TVVL C    G P
Sbjct: 1000 KDDAGRYTCQAVNEAGEDH-MHFELHIL---EQFM---EEIAAVVNSTVVLHC-DVTGQP 1051

Query: 137  EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
             P V W ++GQ +  D   ++   DG  L +   + +D   Y C+A N  GT E  + +L
Sbjct: 1052 TPAVSWLRDGQPVQLDPQHQIS-KDGTQLQLLSVQVSDMAGYLCVAENKVGTVEK-LFSL 1109

Query: 197  KIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR-VKVLD 253
             I + P  I+G   E+     G + +  C V   P P++ W R   G  +  G  V +L 
Sbjct: 1110 TIQVPP-RISGHMEEETSVIEGHTASLLCDVQAYPPPEITWTRD--GQILAFGTGVHILP 1166

Query: 254  DGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS----INLSPNSVNVESGN 308
             G  L+L    L D G+Y C A NS G    S  L+VY  P+    ++ + + V  + G+
Sbjct: 1167 GGQMLQLPRARLEDAGQYVCTATNSAGQDQKSILLSVYVRPTMKPRLDAASDLVTPQVGS 1226

Query: 309  VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV-------FDGVTVLTINDT 361
                +C   G PEP + W   G +     G   D+Y    V       FD   +  +   
Sbjct: 1227 SVTLSCETHGVPEPEVTWYKNGLQLAPRNGFEMDRYQLEIVGVQVRKTFDVTHLRLLECC 1286

Query: 362  DKNDSRNTIVCSAVNYA-----GSSFVRGKLTVTSDDDRP-------PPIITNGP-SNQT 408
              +DSR    C    +      G ++      V    DR        PP++      +  
Sbjct: 1287 QISDSRLNCQCGEFIFGSQVADGGTYTCKVSNVAGQVDRTFRLTVHVPPVLEGSLWESLN 1346

Query: 409  LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTC 467
              + S    PC A   P P I W  +G  +  + +   +  G+ L L  L  +  G YTC
Sbjct: 1347 YTLGSHVSLPCQASGFPVPSITWLKDGTPIESSLQWQWSIRGSRLELGPLALAHGGLYTC 1406

Query: 468  VASSRHGKYVWSGALLVDSPINPNI 492
            +A +  G+     AL V   ++P I
Sbjct: 1407 LAKNSEGQAQKDYALTVQ--VSPTI 1429



 Score =  132 bits (319), Expect = 6e-29
 Identities = 119/401 (29%), Positives = 169/401 (42%), Gaps = 51/401 (12%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            E+P I     +V V  H    L C A G P P+I W + GV + +    S+L  G L F 
Sbjct: 2168 ESPEIRPMAEEVQVVLHHGTVLPCEAQGFPRPSISWQREGVPIATGHRLSLLSNGALKFS 2227

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNA-TLHVAVLREEFRLEPESKQSAQGDTVVLE 128
            R T G    DAG Y C A N  G A  +    LHV  L    + E       QG   +L 
Sbjct: 2228 RVTLG----DAGTYQCLAKNEAGAAVGQTKLVLHVPPLISPAQTE---LSVIQGFQALLS 2280

Query: 129  CLPPRGSPEPNVYWKKNGQ---------TLLFDGDSRMHLVDGGNLVIQ----DARQT-- 173
            C   +GSP+P + W+KNG          T+L  G+  +   +   L++     +A Q   
Sbjct: 2281 CAA-QGSPDPKISWEKNGSPVPNIPGKYTVLRSGELIIERAEVCLLILAALRLEAHQNPL 2339

Query: 174  ----------DAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223
                      DAG + C+A NAAG+       L I+++P     P DV    G S+   C
Sbjct: 2340 NQFWFLTQPADAGLFTCVATNAAGSARQD-RRLSINMRPAFKELPGDVTLNKGQSLALSC 2398

Query: 224  RVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAV 281
               G P P + W  +    N P     V + G  SL ++NV  +D G Y C AEN VG+V
Sbjct: 2399 HAQGTPSPVISWTVN----NSPRQGAAVDEAGRSSLIIENVTTSDAGTYVCVAENRVGSV 2454

Query: 282  SASGYLTVYDPPSINLSPN-SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340
                ++ V +PP +    + S  V  G+     C   G P P + W  +GN  +      
Sbjct: 2455 RTLSFVRVREPPVLKGDAHMSQTVIQGSSTILDCPIHGDPSPVLQWLRDGNALL------ 2508

Query: 341  RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381
               +   A+ +G   L I   + N       C A N AG++
Sbjct: 2509 -RSHRIQALLNG--SLVIYSVNVNTHEGEYQCLAENEAGTA 2546



 Score =  131 bits (317), Expect = 1e-28
 Identities = 124/464 (26%), Positives = 191/464 (41%), Gaps = 40/464 (8%)

Query: 20  DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRS-ILPAGGLFFLRATHGRVHS 78
           +VT +    A L+C+  GS    + WY+ G  + + T RS +LP   L       G    
Sbjct: 1   NVTSSVGAVAVLSCKVEGSVRHNLTWYRAGRAIGAHTGRSKVLPDSSL----QISGVQIQ 56

Query: 79  DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
           DAG Y C ATN++G +R     LHV        + P+S+  ++G+ +   C    GSP P
Sbjct: 57  DAGEYHCVATNAHGDSRI-IVWLHVPE-APSVVIHPQSRVFSRGEEIRFVC-SASGSPPP 113

Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
            ++W      +L     R+++   G L I+ A   DAG Y C+A N AG    ++ +L  
Sbjct: 114 QLFWSHG--NMLLTNRQRLNINHYGVLTIKGALPEDAGNYTCLATNEAGVASQSV-SLTF 170

Query: 199 HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW-RRSAGGGNMPLGRVKVLDDGSL 257
              P +    + +    G+    +C+  G P P V W +     G+ P     V   G L
Sbjct: 171 SEAPRIRVTQQAIHVSVGADAVLECQATGAPPPLVRWFKGEFEVGSTPFAGQDV-HHGDL 229

Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-----NLSPNSVNVESGNVARF 312
            +  V   D G Y+C A +  G  + +  L V   P I     N     + VE G     
Sbjct: 230 HIRGVQEVDAGRYTCVASSPAGTATGTVILKVGAMPKIIGVTSNDKTVKMAVEVGTEVVL 289

Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
            C A G P P + WS  G+     P ++      T +  G   L I D    DS+    C
Sbjct: 290 PCEAQGNPSPLVTWSRNGHP---IPPVTAG---FTVLPSG--SLRITDVRLIDSKR-YTC 340

Query: 373 SAVNYAGSSFVRGKLTVTSDDD-RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431
           +A N AG+  +   L + +    +P   +      QT+ +      PC     P P + W
Sbjct: 341 TAENPAGNVSLSYNLHIQAKPRIQPAATLLKARIGQTVTL------PCVVQGEPSPEVTW 394

Query: 432 YFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
           +  G  +       + N   L +      D GTY CVA++  G+
Sbjct: 395 FHNGLPV------GIKNATPLRIHQAKLGDQGTYRCVATNSAGQ 432



 Score =  130 bits (314), Expect = 2e-28
 Identities = 119/437 (27%), Positives = 173/437 (39%), Gaps = 35/437 (8%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P I E   +VT    Q A L C         + W K G  +  D   ++L  G L     
Sbjct: 1883 PIIRESSSEVTTHIGQDALLPCEVEEESHATVTWRKDGFPITQDNRYTLLSEGSL----R 1938

Query: 72   THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
             HG   SDAG Y+C  +N  G+   R   L V V        P +     G   VL C  
Sbjct: 1939 IHGVQLSDAGRYYCTVSNQAGSDH-RGVELRVFV-GPSISPGPFNVTVTSGIRAVLSC-E 1995

Query: 132  PRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
              G P P V WK+NG  L +        L+  G+LV+      D G ++C A N AG   
Sbjct: 1996 TTGIPSPKVSWKRNGTPLDVSQLSGAFRLLSSGSLVLLSPSNEDEGYFECTAVNEAGEER 2055

Query: 191  SAIATL------KIHIKPYLITGP---EDVVAQTG---SSVTFQCRVGGDPLPDVLWRRS 238
              I  +       + +  +    P   +DV A T    +     C V G P P V W + 
Sbjct: 2056 RVIEVILQDGQTDVCVFMFCSVPPSIEDDVTAVTAVKLAPAVLPCHVHGRPQPTVFWTKG 2115

Query: 239  AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
                +   G  +VL  G L + +V+ +  G Y+C A NS G       L+V + P I   
Sbjct: 2116 GAKLSSRGGTYRVLPTGLLEITSVLPSHAGRYTCSARNSAGVAHKHVSLSVQESPEIRPM 2175

Query: 299  PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
               V V   +     C A G P P++ W  EG    I  G     +  + + +G   L  
Sbjct: 2176 AEEVQVVLHHGTVLPCEAQGFPRPSISWQREG--VPIATG-----HRLSLLSNG--ALKF 2226

Query: 359  NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
            +     D+  T  C A N AG++  + KL +       PP+I+   +  ++     A+  
Sbjct: 2227 SRVTLGDA-GTYQCLAKNEAGAAVGQTKLVL-----HVPPLISPAQTELSVIQGFQALLS 2280

Query: 419  CTAICTPEPIIAWYFEG 435
            C A  +P+P I+W   G
Sbjct: 2281 CAAQGSPDPKISWEKNG 2297



 Score =  125 bits (301), Expect = 8e-27
 Identities = 132/475 (27%), Positives = 192/475 (40%), Gaps = 43/475 (9%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
           +T  EAP I      + V+    A L C+A G+P P +RW+KG   V S          G
Sbjct: 168 LTFSEAPRIRVTQQAIHVSVGADAVLECQATGAPPPLVRWFKGEFEVGSTPFAGQDVHHG 227

Query: 66  LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---- 121
              +R   G    DAG Y C A++  GTA +    L V  + +   +    K        
Sbjct: 228 DLHIR---GVQEVDAGRYTCVASSPAGTA-TGTVILKVGAMPKIIGVTSNDKTVKMAVEV 283

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
           G  VVL C   +G+P P V W +NG  +     +   ++  G+L I D R  D+ RY C 
Sbjct: 284 GTEVVLPC-EAQGNPSPLVTWSRNGHPIP-PVTAGFTVLPSGSLRITDVRLIDSKRYTCT 341

Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
           A N AG   S    L I  KP +      + A+ G +VT  C V G+P P+V W  +   
Sbjct: 342 AENPAG-NVSLSYNLHIQAKPRIQPAATLLKARIGQTVTLPCVVQGEPSPEVTWFHN--- 397

Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
             +P+G   + +   LR+    L D+G Y C A NS G  ++   L       I +  NS
Sbjct: 398 -GLPVG---IKNATPLRIHQAKLGDQGTYRCVATNSAGQETSEIKL------DILVRRNS 447

Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
               S     F    +G P P + W   G    I P  S      +   DG  V+     
Sbjct: 448 AFAHS-----FVFVNSGSPRPKIRWFRNGLE--IHPEQS----DFSVGEDGALVIRAASA 496

Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN-GPSNQTLPIKSMAVFPCT 420
             +       C A N AGS   + +L V    + PP I  +  P N T+ +K      C 
Sbjct: 497 SHS---GDFTCVATNEAGSVERKTRLKV----NVPPEIQDDTQPLNLTVTLKQPLTLGCD 549

Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
           A   P P I W  +G  +          +  L +  +    +G ++C A +  G+
Sbjct: 550 AFGIPSPTITWSKDGHPVDTPGVYLQNGNRMLRIYRVQPEHAGRFSCTAQNSAGE 604



 Score =  120 bits (288), Expect = 3e-25
 Identities = 136/500 (27%), Positives = 196/500 (39%), Gaps = 56/500 (11%)

Query: 17   QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV 76
            QPL++TV   QP TL C A G PSP I W K G  V  DT    L  G    LR    RV
Sbjct: 532  QPLNLTVTLKQPLTLGCDAFGIPSPTITWSKDGHPV--DTPGVYLQNGNR-MLRIY--RV 586

Query: 77   HSD-AGVYWCEATNSYGTARSRNATL----HVAVLREEFRLEPESKQSAQ-----GDTVV 126
              + AG + C A NS G AR   + +    H+       R    S  +A+     G  V 
Sbjct: 587  QPEHAGRFSCTAQNSAGEARREYSIVVQGKHIKQPPLTTRTLTMSVSNAELTVALGQEVE 646

Query: 127  LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCIARNA 185
             +C   RG P P V W ++G+ L  DGD  +    DG  L ++  R  D G YQC+A N 
Sbjct: 647  FQC-QVRGKPPPRVEWSRDGEVLSRDGDPHVEFHEDGQVLKVKAVRLRDQGIYQCLASNN 705

Query: 186  AGTRESAI-ATLKIH------IKPYLITGP---EDVVAQTGSSVTFQCRVGGDPLPDVLW 235
            AGT+      T+++       + P  I GP    +V    G S    C V G P P + W
Sbjct: 706  AGTQMRQFRLTVQVRTIVVVCLSPPTIKGPSETSEVSVVLGFSTLLSCDVEGSPTPSITW 765

Query: 236  RRSAGGGNMPLGRVKVL----DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
             +     N P+     L       +LRL +V     G Y+C A N  G       L V  
Sbjct: 766  LKD----NQPIVSSPQLTYTRGGQALRLGSVQGDSTGLYTCRATNPAGTAIKHYSLVVLV 821

Query: 292  PPSIN-----LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI--IFPGMSRDKY 344
            PP I         +   V        +C   G PEP + W  +G      +  G+    +
Sbjct: 822  PPQIEGDSPVFGTHEEKVRMNGSLTLSCMTKGFPEPKIQWFKDGQLLTGSVHTGIQELGH 881

Query: 345  -----HATAVFDGVTVLTINDT---DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP 396
                 +   V +G     + ++   DK D   TI    V +  ++           DD  
Sbjct: 882  SLLIENTMLVHEGQYTCVVTNSAGEDKRDFHVTIQVPPVFHRVTNREAAWGLGHEGDDED 941

Query: 397  PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLK 455
              +         + +       C +   P P ++W+ +G+ L+      +   G  L + 
Sbjct: 942  DTV-----EKLDVVLGHPVSLSCESNAIPPPKLSWHKDGQKLLSGDGVVLLPGGQVLQIA 996

Query: 456  DLDKSDSGTYTCVASSRHGK 475
             + K D+G YTC A +  G+
Sbjct: 997  RVRKDDAGRYTCQAVNEAGE 1016



 Score =  119 bits (286), Expect = 6e-25
 Identities = 121/465 (26%), Positives = 189/465 (40%), Gaps = 43/465 (9%)

Query: 37  GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
           GSP P IRW++ G+ +  +     +   G   +RA      S +G + C ATN  G+   
Sbjct: 459 GSPRPKIRWFRNGLEIHPEQSDFSVGEDGALVIRAASA---SHSGDFTCVATNEAGSVE- 514

Query: 97  RNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155
           R   L V V  E +   +P +        + L C    G P P + W K+G  +   G  
Sbjct: 515 RKTRLKVNVPPEIQDDTQPLNLTVTLKQPLTLGC-DAFGIPSPTITWSKDGHPVDTPG-- 571

Query: 156 RMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGT--RESAIATLKIHIK-PYLIT----- 206
            ++L +G  ++ I   +   AGR+ C A+N+AG   RE +I     HIK P L T     
Sbjct: 572 -VYLQNGNRMLRIYRVQPEHAGRFSCTAQNSAGEARREYSIVVQGKHIKQPPLTTRTLTM 630

Query: 207 --GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGS-LRLDNV 262
                ++    G  V FQC+V G P P V W R     +      V+  +DG  L++  V
Sbjct: 631 SVSNAELTVALGQEVEFQCQVRGKPPPRVEWSRDGEVLSRDGDPHVEFHEDGQVLKVKAV 690

Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVY---------DPPSIN--LSPNSVNVESGNVAR 311
            L D+G Y C A N+ G       LTV           PP+I      + V+V  G    
Sbjct: 691 RLRDQGIYQCLASNNAGTQMRQFRLTVQVRTIVVVCLSPPTIKGPSETSEVSVVLGFSTL 750

Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371
            +C   G P P++ W  +    +  P ++  +        G   L +    + DS     
Sbjct: 751 LSCDVEGSPTPSITWLKDNQPIVSSPQLTYTR--------GGQALRLGSV-QGDSTGLYT 801

Query: 372 CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431
           C A N AG++     L V             G   + + +       C     PEP I W
Sbjct: 802 CRATNPAGTAIKHYSLVVLVPPQIEGDSPVFGTHEEKVRMNGSLTLSCMTKGFPEPKIQW 861

Query: 432 YFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGK 475
           + +G+ L  +    +   G +L++++      G YTCV ++  G+
Sbjct: 862 FKDGQLLTGSVHTGIQELGHSLLIENTMLVHEGQYTCVVTNSAGE 906



 Score =  118 bits (284), Expect = 1e-24
 Identities = 117/421 (27%), Positives = 175/421 (41%), Gaps = 40/421 (9%)

Query: 78   SDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
            +D G Y C+ +N  G   R+   T+HV  + E    E  S     G  V L C    G P
Sbjct: 1307 ADGGTYTCKVSNVAGQVDRTFRLTVHVPPVLEGSLWE--SLNYTLGSHVSLPC-QASGFP 1363

Query: 137  EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
             P++ W K+G T +         + G  L +        G Y C+A+N+ G  +   A L
Sbjct: 1364 VPSITWLKDG-TPIESSLQWQWSIRGSRLELGPLALAHGGLYTCLAKNSEGQAQKDYA-L 1421

Query: 197  KIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR-VKVLD 253
             + + P ++    P +V A  G  +T +CR  G+P P + W +          R + V  
Sbjct: 1422 TVQVSPTILDSEHPSEVSAPMGEDMTLECRAAGNPTPHLSWLKDGVTVEGSDSRHIGVTP 1481

Query: 254  DGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN---LSPNSVNVESGNV 309
            +GS L L  +   D G Y+C A +  G  +    L V  PPSI+     P  V V     
Sbjct: 1482 EGSTLTLLRLSPDDSGTYTCLAVSPAGRQTKIYTLFVLVPPSISGETTVPREVQVTQDGA 1541

Query: 310  ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
                C A G P P + W   G+  ++    SR     T +    +VL I+    +DS   
Sbjct: 1542 VTLECQAVGSPPPQISWLKNGHPLLL---SSR-----TRLLSADSVLRISPVQLSDS-GV 1592

Query: 370  IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
              C A + AG + +   + V  +    P  I  G         S+    C A   P P +
Sbjct: 1593 YTCMARSQAGLAELSYDVQVQVE----PVTIVQG---------SLVTLSCEARGVPPPTL 1639

Query: 430  AWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
             W  +G+ L  +  RN+  DG    L L D+  SD+G Y+CVAS++ G    +  L V  
Sbjct: 1640 TWLKDGQPL--SLHRNLLLDGQETRLQLPDVGPSDAGLYSCVASNQAGSSTKTFNLTVLE 1697

Query: 487  P 487
            P
Sbjct: 1698 P 1698



 Score = 97.5 bits (232), Expect = 2e-18
 Identities = 69/232 (29%), Positives = 109/232 (46%), Gaps = 14/232 (6%)

Query: 13   YIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            +I+EQ ++ +    +    L+C   G P+PA+ W + G  V  D    I   G    L +
Sbjct: 1024 HILEQFMEEIAAVVNSTVVLHCDVTGQPTPAVSWLRDGQPVQLDPQHQISKDGTQLQLLS 1083

Query: 72   THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
                  SD   Y C A N  GT     +       R    +E E+    +G T  L C  
Sbjct: 1084 VQV---SDMAGYLCVAENKVGTVEKLFSLTIQVPPRISGHMEEETSV-IEGHTASLLC-D 1138

Query: 132  PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRE 190
             +  P P + W ++GQ L F   + +H++ GG ++ +  AR  DAG+Y C A N+AG  +
Sbjct: 1139 VQAYPPPEITWTRDGQILAFG--TGVHILPGGQMLQLPRARLEDAGQYVCTATNSAGQDQ 1196

Query: 191  SAIATLKIHIKPYL---ITGPEDVVA-QTGSSVTFQCRVGGDPLPDVLWRRS 238
             +I  L ++++P +   +    D+V  Q GSSVT  C   G P P+V W ++
Sbjct: 1197 KSIL-LSVYVRPTMKPRLDAASDLVTPQVGSSVTLSCETHGVPEPEVTWYKN 1247



 Score = 93.5 bits (222), Expect = 3e-17
 Identities = 86/306 (28%), Positives = 143/306 (46%), Gaps = 39/306 (12%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFF-- 68
            P I     +++V +   A L+C A GSP P I W K G  V +   + ++L +G L    
Sbjct: 2260 PLISPAQTELSVIQGFQALLSCAAQGSPDPKISWEKNGSPVPNIPGKYTVLRSGELIIER 2319

Query: 69   -------LRATHGRVH-------------SDAGVYWCEATNSYGTAR-SRNATLHVAVLR 107
                   L A     H             +DAG++ C ATN+ G+AR  R  +++   +R
Sbjct: 2320 AEVCLLILAALRLEAHQNPLNQFWFLTQPADAGLFTCVATNAAGSARQDRRLSIN---MR 2376

Query: 108  EEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVI 167
              F+  P      +G ++ L C   +G+P P + W  N         + +      +L+I
Sbjct: 2377 PAFKELPGDVTLNKGQSLALSC-HAQGTPSPVISWTVNNSP---RQGAAVDEAGRSSLII 2432

Query: 168  QDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT---GSSVTFQCR 224
            ++   +DAG Y C+A N  G+  + ++ +++  +P ++ G +  ++QT   GSS    C 
Sbjct: 2433 ENVTTSDAGTYVCVAENRVGSVRT-LSFVRVR-EPPVLKG-DAHMSQTVIQGSSTILDCP 2489

Query: 225  VGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNV-ILADEGEYSCEAENSVGAVSA 283
            + GDP P + W R  G   +   R++ L +GSL + +V +   EGEY C AEN  G    
Sbjct: 2490 IHGDPSPVLQWLRD-GNALLRSHRIQALLNGSLVIYSVNVNTHEGEYQCLAENEAGTAER 2548

Query: 284  SGYLTV 289
            +  L V
Sbjct: 2549 TIALKV 2554



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 1/65 (1%)

Query: 424 TPEPIIAWYFEG-EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482
           +P P I W+  G E   +    +V  DG LV++    S SG +TCVA++  G       L
Sbjct: 460 SPRPKIRWFRNGLEIHPEQSDFSVGEDGALVIRAASASHSGDFTCVATNEAGSVERKTRL 519

Query: 483 LVDSP 487
            V+ P
Sbjct: 520 KVNVP 524


>UniRef50_UPI0000E48C89 Cluster: PREDICTED: similar to Nr-CAM
           protein; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to Nr-CAM protein -
           Strongylocentrotus purpuratus
          Length = 1235

 Score =  159 bits (385), Expect = 6e-37
 Identities = 133/474 (28%), Positives = 196/474 (41%), Gaps = 21/474 (4%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLR 70
           P I+EQP  +      P TL CRA G P P+  WYK G L  V +  R+ L  G L    
Sbjct: 24  PSIVEQPESINGDTRLPLTLTCRATGIPEPSYYWYKDGALFDVDNNDRASLDGGNLVIES 83

Query: 71  ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC- 129
            T     +D G Y C A N  GTA S+     +A + +     PE+ Q  QG  + L C 
Sbjct: 84  LT----TADDGQYQCFANNRLGTAMSQKIMTSLAFMDQFENTAPETIQVDQGRPLKLRCG 139

Query: 130 -LP--PRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN- 184
             P  P G+P P +YW     +      ++R++    GNLV  +   +DA  Y C A N 
Sbjct: 140 GSPGVPNGNPAPLIYWTDAAAKPTPITYNARINQDPEGNLVFSNVIASDAKGYYCQAINN 199

Query: 185 -AAGTRESAIATLKIHIK--PYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
               ++ +   TL + ++    LIT P  + +A        +C   G P P + W+R   
Sbjct: 200 VVGSSQRTPKVTLMVSVESGASLITKPAANEIAIRTQLFKLKCIAYGYPTPVITWKRGEE 259

Query: 241 GGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
                 GRV + + G  L +  V  +D+G Y+C A N+ G    S  +TV   P     P
Sbjct: 260 QLQSG-GRVSIEESGQELVISTVENSDKGTYTCVASNTGGDDEFSTVVTVESAPYFPAPP 318

Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF-PGMSRDKYHATAVFDGVTVLTI 358
           +      G      C + G P P + W V G     F   +  +++        +  ++I
Sbjct: 319 SDETKGPGESVDIECRSEGVPAPAVDWLVNGQPWADFESNIDTERWTVVTGNPQLATISI 378

Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
           ++    DS N   C A N          L V S   R P   T      ++   S A F 
Sbjct: 379 SNLQTTDS-NVFQCIATNKYKEELTSVVLNVVSIPARIPS-FTPVTRKLSVVEDSSAAFT 436

Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTN-DGTLVLKDLDKSDSGTYTCVASS 471
           C     P P I W F+G  L    +  +    G++V+ +  + DSG Y C A +
Sbjct: 437 CHVEGRPTPTITWTFKGSVLTNGDKYTIDELAGSIVINNALEVDSGAYECTAEN 490



 Score =  109 bits (262), Expect = 5e-22
 Identities = 128/481 (26%), Positives = 196/481 (40%), Gaps = 57/481 (11%)

Query: 18  PLDVTVARHQPATLNCRAG-----GSPSPAIRWYKGGVLVVSDTHRSIL---PAGGLFFL 69
           P  + V + +P  L C        G+P+P I W          T+ + +   P G L F 
Sbjct: 123 PETIQVDQGRPLKLRCGGSPGVPNGNPAPLIYWTDAAAKPTPITYNARINQDPEGNLVFS 182

Query: 70  RATHGRVHSDAGVYWCEATNSY--GTARSRNATLHVAVLREEFRL-EPESKQSA-QGDTV 125
                 + SDA  Y+C+A N+    + R+   TL V+V      + +P + + A +    
Sbjct: 183 NV----IASDAKGYYCQAINNVVGSSQRTPKVTLMVSVESGASLITKPAANEIAIRTQLF 238

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARN 184
            L+C+   G P P + WK+  + L   G  R+ + + G  LVI     +D G Y C+A N
Sbjct: 239 KLKCIA-YGYPTPVITWKRGEEQLQSGG--RVSIEESGQELVISTVENSDKGTYTCVASN 295

Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--- 241
             G  E +   + +   PY    P D     G SV  +CR  G P P V W  +      
Sbjct: 296 TGGDDEFS-TVVTVESAPYFPAPPSDETKGPGESVDIECRSEGVPAPAVDWLVNGQPWAD 354

Query: 242 --GNMPLGRVKVLDDG----SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-P-- 292
              N+   R  V+       ++ + N+   D   + C A N       S  L V   P  
Sbjct: 355 FESNIDTERWTVVTGNPQLATISISNLQTTDSNVFQCIATNKYKEELTSVVLNVVSIPAR 414

Query: 293 -PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
            PS       ++V   + A FTC   GRP PT+ W+ +G+  ++  G   DKY    +  
Sbjct: 415 IPSFTPVTRKLSVVEDSSAAFTCHVEGRPTPTITWTFKGS--VLTNG---DKYTIDELAG 469

Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYA-GSSF-VRGKLTVTSDDDRPPPIITNGPSNQTL 409
            +    IN+  + DS     C+A N   G  +   G  T+T        IIT  P++ T+
Sbjct: 470 SIV---INNALEVDS-GAYECTAENSIDGQDYEATGSATLTV---LGKTIITLPPADLTV 522

Query: 410 PIKSMAVFPCTAICTPE---PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYT 466
              + A F C      E   P   W  +G+ L  N   ++  D  +       S+SGTYT
Sbjct: 523 REDTTATFQCEITYDHELDKPETYWMKDGQRLEANQDNSLRIDNAMF------SNSGTYT 576

Query: 467 C 467
           C
Sbjct: 577 C 577



 Score =  108 bits (259), Expect = 1e-21
 Identities = 109/399 (27%), Positives = 165/399 (41%), Gaps = 43/399 (10%)

Query: 115 ESKQSAQGDTVVLECLPPR--GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ 172
           E  +S  GDT +   L  R  G PEP+ YW K+G     D + R  L DGGNLVI+    
Sbjct: 28  EQPESINGDTRLPLTLTCRATGIPEPSYYWYKDGALFDVDNNDRASL-DGGNLVIESLTT 86

Query: 173 TDAGRYQCIARNAAGTRESA-IATLKIHIKPYLITGPEDVVAQTGSSVTFQCR-----VG 226
            D G+YQC A N  GT  S  I T    +  +  T PE +    G  +  +C        
Sbjct: 87  ADDGQYQCFANNRLGTAMSQKIMTSLAFMDQFENTAPETIQVDQGRPLKLRCGGSPGVPN 146

Query: 227 GDPLPDVLWRRSAGGGNMPLGRVKVLDD--GSLRLDNVILADEGEYSCEAENSV-GAVSA 283
           G+P P + W  +A          ++  D  G+L   NVI +D   Y C+A N+V G+   
Sbjct: 147 GNPAPLIYWTDAAAKPTPITYNARINQDPEGNLVFSNVIASDAKGYYCQAINNVVGSSQR 206

Query: 284 SGYLT----VYDPPSINLSP--NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337
           +  +T    V    S+   P  N + + +  + +  C A G P P + W   G   +   
Sbjct: 207 TPKVTLMVSVESGASLITKPAANEIAIRT-QLFKLKCIAYGYPTPVITWK-RGEEQLQSG 264

Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397
           G         ++ +    L I+ T +N  + T  C A N  G       +TV S    P 
Sbjct: 265 GR-------VSIEESGQELVIS-TVENSDKGTYTCVASNTGGDDEFSTVVTVESAPYFPA 316

Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG------EALIQNHRRNVTNDG- 450
           P     PS++T          C +   P P + W   G      E+ I   R  V     
Sbjct: 317 P-----PSDETKGPGESVDIECRSEGVPAPAVDWLVNGQPWADFESNIDTERWTVVTGNP 371

Query: 451 ---TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
              T+ + +L  +DS  + C+A++++ + + S  L V S
Sbjct: 372 QLATISISNLQTTDSNVFQCIATNKYKEELTSVVLNVVS 410



 Score =  106 bits (255), Expect = 3e-21
 Identities = 78/304 (25%), Positives = 131/304 (43%), Gaps = 16/304 (5%)

Query: 192 AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
           A  TL   + P ++  PE +   T   +T  CR  G P P   W +     ++       
Sbjct: 14  ATLTLAYDVPPSIVEQPESINGDTRLPLTLTCRATGIPEPSYYWYKDGALFDVDNNDRAS 73

Query: 252 LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT--VYDPPSINLSPNSVNVESGNV 309
           LD G+L ++++  AD+G+Y C A N +G   +   +T   +     N +P ++ V+ G  
Sbjct: 74  LDGGNLVIESLTTADDGQYQCFANNRLGTAMSQKIMTSLAFMDQFENTAPETIQVDQGRP 133

Query: 310 ARFTCTAT-----GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
            +  C  +     G P P ++W+    +           Y+A    D    L  ++   +
Sbjct: 134 LKLRCGGSPGVPNGNPAPLIYWTDAAAKPTPIT------YNARINQDPEGNLVFSNVIAS 187

Query: 365 DSRNTIVCSAVN-YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
           D++    C A+N   GSS    K+T+    +    +IT   +N+      +    C A  
Sbjct: 188 DAKG-YYCQAINNVVGSSQRTPKVTLMVSVESGASLITKPAANEIAIRTQLFKLKCIAYG 246

Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482
            P P+I W    E L    R ++   G  LV+  ++ SD GTYTCVAS+  G   +S  +
Sbjct: 247 YPTPVITWKRGEEQLQSGGRVSIEESGQELVISTVENSDKGTYTCVASNTGGDDEFSTVV 306

Query: 483 LVDS 486
            V+S
Sbjct: 307 TVES 310



 Score = 95.9 bits (228), Expect = 6e-18
 Identities = 81/308 (26%), Positives = 132/308 (42%), Gaps = 28/308 (9%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-----DTHRSI 60
           VT   APY    P D T    +   + CR+ G P+PA+ W   G          DT R  
Sbjct: 306 VTVESAPYFPAPPSDETKGPGESVDIECRSEGVPAPAVDWLVNGQPWADFESNIDTERWT 365

Query: 61  LPAGGLFFLRATHGRVH-SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPES-KQ 118
           +  G       +   +  +D+ V+ C ATN Y    +      V++        P + K 
Sbjct: 366 VVTGNPQLATISISNLQTTDSNVFQCIATNKYKEELTSVVLNVVSIPARIPSFTPVTRKL 425

Query: 119 SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY 178
           S   D+         G P P + W   G ++L +GD        G++VI +A + D+G Y
Sbjct: 426 SVVEDSSAAFTCHVEGRPTPTITWTFKG-SVLTNGDKYTIDELAGSIVINNALEVDSGAY 484

Query: 179 QCIARNAAGTRE---SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD---PLPD 232
           +C A N+   ++   +  ATL +  K  +   P D+  +  ++ TFQC +  D     P+
Sbjct: 485 ECTAENSIDGQDYEATGSATLTVLGKTIITLPPADLTVREDTTATFQCEITYDHELDKPE 544

Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSC-------EAENSVGAVSASG 285
             W +          R++   D SLR+DN + ++ G Y+C       E+ ++V +V+AS 
Sbjct: 545 TYWMKDG-------QRLEANQDNSLRIDNAMFSNSGTYTCFVETTLDESTDTVHSVNASA 597

Query: 286 YLTVYDPP 293
            L V   P
Sbjct: 598 QLVVKGHP 605



 Score = 44.8 bits (101), Expect = 0.015
 Identities = 31/147 (21%), Positives = 57/147 (38%), Gaps = 6/147 (4%)

Query: 689 VSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTV 748
           +  F + + + Y +YEF +        G         + +  P   P  + +  ++   V
Sbjct: 758 IQNFIVNARKPYEEYEFSVRSMNSGGPGPEPEIHYGFSGEAAPGASPSGVTVEAISANEV 817

Query: 749 HLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSV 808
           ++ W P + +  NG + GYNV  N          + +       +  ++ NL +  +Y +
Sbjct: 818 NVTWEPIDPEDANGKLGGYNVYYNVKIASGQDKQMCVK------SPCVVGNLQAATTYEI 871

Query: 809 QIAAETIIGLGPFSQKVYFNIDSRSVG 835
            + A T  G GP S  V    DS   G
Sbjct: 872 TVKAFTNAGEGPASDVVEVVTDSAPPG 898



 Score = 39.9 bits (89), Expect = 0.41
 Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 4/78 (5%)

Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
           + +L+  T YE  +  F    EG P++  V    D  P GP   +++ + +   V L W 
Sbjct: 860 VGNLQAATTYEITVKAFTNAGEG-PASDVVEVVTDSAPPGPVYKLKVDVYSYRLV-LNWQ 917

Query: 754 PPELQLQNGIITGYNVVV 771
            P L   NG +TGYNV++
Sbjct: 918 EPILT--NGDLTGYNVII 933


>UniRef50_Q12860 Cluster: Contactin-1 precursor; n=31;
           Euteleostomi|Rep: Contactin-1 precursor - Homo sapiens
           (Human)
          Length = 1018

 Score =  159 bits (385), Expect = 6e-37
 Identities = 139/497 (27%), Positives = 210/497 (42%), Gaps = 48/497 (9%)

Query: 9   GEAPYIIEQPLDVTVARHQ---PATLNCRAGGSPSPAIRWY--KGGVLVVSDTHRSILPA 63
           G  P   EQP++            +LNCRA  SP P  +W    G V + SD +  +   
Sbjct: 38  GFGPIFEEQPINTIYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMV--- 94

Query: 64  GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
           GG   +     +   DAG+Y+C A+N+YG  RS  ATL    L      E    +  +G 
Sbjct: 95  GGNLVINNPDKQ--KDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGK 152

Query: 124 TVVLECLPPRGSPEPNVY-WKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCI 181
            +VL C PP   P+   Y W  N   +    D R  +    GNL I +   +D G Y C 
Sbjct: 153 GMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCF 212

Query: 182 ARNAAGTR---ESAIATLKI---HIKPY---LITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
             + + T+      I  + I     KPY   ++   +DV A  G +VT +C   G+P+PD
Sbjct: 213 VSSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPD 272

Query: 233 VLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
           + WR+      MP    ++   G+ L++ N+ L DEG Y CEAEN  G       + V  
Sbjct: 273 IRWRKVL--EPMP-STAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQA 329

Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
            P      N   V+ G+   + C ATG+P PT+ W   G             YH      
Sbjct: 330 FPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGY-----------AYHKGE--- 375

Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
               L + D    ++     C A N  G+ +   +L + +     P    N    + L  
Sbjct: 376 ----LRLYDV-TFENAGMYQCIAENTYGAIYANAELKILA---LAPTFEMNPMKKKILAA 427

Query: 412 K-SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470
           K    +  C     P+P  +W    E L+ + R  +  DG+L + ++ ++D G YTC A 
Sbjct: 428 KGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAE 487

Query: 471 SRHGKYVWSGALLVDSP 487
           +  GK   +G L++  P
Sbjct: 488 NNRGKANSTGTLVITDP 504



 Score =  115 bits (276), Expect = 9e-24
 Identities = 119/446 (26%), Positives = 188/446 (42%), Gaps = 36/446 (8%)

Query: 14  IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
           I+ Q  DV     Q  TL C A G+P P IRW K  VL    +   I  +G +  L+  +
Sbjct: 244 IVVQFKDVYALMGQNVTLECFALGNPVPDIRWRK--VLEPMPSTAEISTSGAV--LKIFN 299

Query: 74  GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
            ++  D G+Y CEA N  G  + + A ++V    E      +++    G  +   C+   
Sbjct: 300 IQLE-DEGIYECEAENIRGKDKHQ-ARIYVQAFPEWVEHINDTEVDI-GSDLYWPCVAT- 355

Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
           G P P + W KNG           +    G L + D    +AG YQCIA N  G    A 
Sbjct: 356 GKPIPTIRWLKNG-----------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIY-AN 403

Query: 194 ATLKI-HIKPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250
           A LKI  + P     P  + ++A  G  V  +C+    P P   W +      +   R+ 
Sbjct: 404 AELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEW-LVNSSRIL 462

Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310
           + +DGSL ++N+   D G Y+C AEN+ G  +++G L + DP  I L+P + ++  G  A
Sbjct: 463 IWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENA 522

Query: 311 RFTCTATGRP--EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD-KNDSR 367
              C A+  P  + T  WS  G   +I        Y    + D    L I +   K+  R
Sbjct: 523 TMQCAASFDPALDLTFVWSFNG--YVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGR 580

Query: 368 NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427
            T  C+A     +S     L V     R PP    G   + +   S+A+          P
Sbjct: 581 YT--CTAQTIVDNSSASADLVV-----RGPPGPPGGLRIEDIRATSVALTWSRGSDNHSP 633

Query: 428 IIAWYFEGEALIQNHRRNVTNDGTLV 453
           I  +  + + ++ +  ++   D  ++
Sbjct: 634 ISKYTIQTKTILSDDWKDAKTDPPII 659



 Score =  112 bits (269), Expect = 6e-23
 Identities = 167/723 (23%), Positives = 274/723 (37%), Gaps = 101/723 (13%)

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
           G  V LEC    G+P P++ W+K  + +    +       G  L I + +  D G Y+C 
Sbjct: 256 GQNVTLECFA-LGNPVPDIRWRKVLEPMPSTAEIS---TSGAVLKIFNIQLEDEGIYECE 311

Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
           A N  G ++   A + +   P  +    D     GS + + C   G P+P + W ++   
Sbjct: 312 AENIRG-KDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNG-- 368

Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLSPN 300
                        G LRL +V   + G Y C AEN+ GA+ A+  L +    P+  ++P 
Sbjct: 369 --------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPM 420

Query: 301 SVNVESGNVAR--FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
              + +    R    C     P+P   WS +G   ++      +        DG   L I
Sbjct: 421 KKKILAAKGGRVIIECKPKAAPKPKFSWS-KGTEWLV------NSSRILIWEDGS--LEI 471

Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
           N+  +ND      C A N  G +   G L +T      P  I   P N  + +   A   
Sbjct: 472 NNITRNDG-GIYTCFAENNRGKANSTGTLVITD-----PTRIILAPINADITVGENATMQ 525

Query: 419 CTAICTP--EPIIAWYFEGEALIQN-----HRRN--VTNDGTLVLKDLDKSDSGTYTCVA 469
           C A   P  +    W F G  +  N     ++RN  + ++G L++++     +G YTC A
Sbjct: 526 CAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTA 585

Query: 470 SSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
            +       S  L+V  P                PGPP      ++  TSV L+WS+ + 
Sbjct: 586 QTIVDNSSASADLVVRGP----------------PGPPGGLRIEDIRATSVALTWSRGSD 629

Query: 530 IGSSSILGYQVE---VFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFI 586
              S I  Y ++   + S +       P    G +  AR V         LIP + Y F 
Sbjct: 630 -NHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAV--------DLIPWMEYEFR 680

Query: 587 VRTENSHGLSGPSPVSDSV-TVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPID 645
           V   N+ G   PS  S+ + T G   N      G       RN  LT      I   P+ 
Sbjct: 681 VVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGG---RNRELT------ITWAPLS 731

Query: 646 SKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEI---TSLRKYTK 702
            +     +   N +   G  + F+P D      E K +  +N  +G  +    ++   T 
Sbjct: 732 RE-----YHYGNNF---GYIVAFKPFDG----EEWKKVTVTNPDTGRYVHKDETMSPSTA 779

Query: 703 YEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNG 762
           ++  +  F  K +G  S   V  +  D P   P  + + +L+++ + + W      +   
Sbjct: 780 FQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWE----HVLEK 835

Query: 763 IITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFS 822
           I+  Y +   W      ++   +  T  Q  S  + NL     Y +++ A    G GP S
Sbjct: 836 IVESYQIRY-WAAHDKEEAANRVQVT-SQEYSARLENLLPDTQYFIEVGACNSAGCGPPS 893

Query: 823 QKV 825
             +
Sbjct: 894 DMI 896



 Score = 39.9 bits (89), Expect = 0.41
 Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 6/91 (6%)

Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSM---AVFPCTAICTPEPIIAWYFE-GEALIQNHRR 444
           V+ +D    PI    P N   P +S+       C A  +P P+  W    G+  + + R 
Sbjct: 32  VSEEDKGFGPIFEEQPINTIYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRY 91

Query: 445 NVTNDGTLVLKDLDKS-DSGTYTCVASSRHG 474
           ++   G LV+ + DK  D+G Y C+AS+ +G
Sbjct: 92  SMVG-GNLVINNPDKQKDAGIYYCLASNNYG 121


>UniRef50_UPI0000D57997 Cluster: PREDICTED: similar to CG33519-PB;
            n=2; Tribolium castaneum|Rep: PREDICTED: similar to
            CG33519-PB - Tribolium castaneum
          Length = 4089

 Score =  157 bits (380), Expect = 2e-36
 Identities = 157/619 (25%), Positives = 246/619 (39%), Gaps = 59/619 (9%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWYKGGV--LVVSDTHRSILPAGGLFFLRATHGRVH 77
            DV +   +   L  +    P P ++W K GV   V S+ H  + P G +  +        
Sbjct: 2353 DVKLPIGETLRLEAQVQAHPPPEVKWIKDGVPVRVSSNIHFEVHPDGKVALI--VDCAKP 2410

Query: 78   SDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
             +AG Y  + +N YG A    +  +     + EF +    +   +G  V  E +   G P
Sbjct: 2411 ENAGKYELQVSNKYGDAMGEASVEIEKKPTKPEFLVRLVPQTVVEGFPVKFE-VKAVGHP 2469

Query: 137  EPNVYWKKNGQTLLFDGD--SRMHLVDGGNLVIQDA--RQTDAGRYQCIARNAAGTRESA 192
             P + W +NG  ++ D        L DG ++++ DA  +  D   Y+ IA N AG  E++
Sbjct: 2470 APKLTWSRNGAEVISDNKHVKISELPDGTSVLLLDAANQARDGLTYRAIAINEAGEAETS 2529

Query: 193  IATLKIHI--------KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
                 I          KP  +   +DV A  G S+        +P+P V W +  G    
Sbjct: 2530 APLTVIPATNSESPEEKPMFLHPLKDVTADEGKSLVLSAPFTANPVPMVEWSKD-GVPLS 2588

Query: 245  PLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLS 298
            P  R+ V  DG    L + N + +D G YS +  N +G  S+     V+    PP    +
Sbjct: 2589 PSDRILVTCDGKKVGLEILNAVPSDAGRYSVKISNPLGEESSEANAAVHKVFMPPHFTQT 2648

Query: 299  PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
               +    G  A+F C  +G P+P + W+ +G      P    DKYH     D   +  +
Sbjct: 2649 FTDLQQLPGRDAKFPCRVSGVPQPEVVWTKDG-----LPIKESDKYHIKRDGDLCCLYVL 2703

Query: 359  NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP----PPIITNGPSNQTLPIKSM 414
            N +   D        A+N  G       L V           PP       +  L     
Sbjct: 2704 NCSP--DDAAVYRARAINKEGEEVCTASLEVVDQIQAKKKIEPPTFLKRIGDTELFKGMT 2761

Query: 415  AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT----LVLKDLDKSDSGTYTCVAS 470
            A F   A   PEP + WY   + L  ++R  +  D      L++ DLD++D G Y+C  +
Sbjct: 2762 AKFTACASGYPEPEVEWYHNDQKLFPSNRIKMETDPNGLLRLIISDLDEADLGKYSCKIT 2821

Query: 471  SRHGKYVWSGALLVDS--------PINPNIHFFRAADVSSLPGPPTKP-ITHNVTDTSVT 521
            + +G  +    L +D         PI      F     +  P P + P I   +TD   T
Sbjct: 2822 NEYGGDICHANLNMDEGLETRAKRPITDQYTEFDKYKRTGAPVPLSDPPIISQMTDRHCT 2881

Query: 522  LSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGI 581
            LSW  +   G  + + YQ+E+   E  +G+        W  +   +      V++L P  
Sbjct: 2882 LSWKPSIPPGPRAPVTYQLEMC--ELPNGD--------WFTVRTGIRSCTCGVRNLEPFR 2931

Query: 582  TYMFIVRTENSHGLSGPSP 600
             Y F VR EN +G+S PSP
Sbjct: 2932 DYKFRVRVENKYGISDPSP 2950



 Score =  115 bits (276), Expect = 9e-24
 Identities = 137/523 (26%), Positives = 215/523 (41%), Gaps = 33/523 (6%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-THRSILPAGGLFF 68
            E P II    D  V   +  ++  RA G P P IRW   G  +V D  H+    A     
Sbjct: 2149 EKPTIITGLSDDQVEHTKEISVMVRADGLPKPQIRWLLNGKPIVEDEKHKIESHADAQVT 2208

Query: 69   LRATHGRVH-SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPE-SKQSAQGDTVV 126
               T    + SD+G+Y   A N  G A   +A + +      F  + E S+   +G+ + 
Sbjct: 2209 STLTVSDFNDSDSGIYKAIAANVQGEA-DTSARITMVQTPPTFGKKLERSEDVIEGEPLE 2267

Query: 127  LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNA 185
            L+     GSP+P V W KNG+ +  +      L DG   L I+ AR +D+G Y+ + +N 
Sbjct: 2268 LKA-KINGSPKPTVVWYKNGEPIDDERVKTSVLPDGTVKLNIEHARPSDSGAYKLVIQNP 2326

Query: 186  AGTRE--SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
             G      A+A  +   +P  +   +DV    G ++  + +V   P P+V W +      
Sbjct: 2327 NGESACLCAVAVQQKPQRPKFLKCFKDVKLPIGETLRLEAQVQAHPPPEVKWIKDGVPVR 2386

Query: 244  MPLG-RVKVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS-----I 295
            +      +V  DG + L  D     + G+Y  +  N  G       + +   P+     +
Sbjct: 2387 VSSNIHFEVHPDGKVALIVDCAKPENAGKYELQVSNKYGDAMGEASVEIEKKPTKPEFLV 2446

Query: 296  NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY-HATAVFDGVT 354
             L P +V VE G   +F   A G P P + WS  G   I     S +K+   + + DG +
Sbjct: 2447 RLVPQTV-VE-GFPVKFEVKAVGHPAPKLTWSRNGAEVI-----SDNKHVKISELPDGTS 2499

Query: 355  VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV----TSDDDRPPPIITNGPSNQTLP 410
            VL ++  ++     T    A+N AG +     LTV     S+     P+  +   + T  
Sbjct: 2500 VLLLDAANQARDGLTYRAIAINEAGEAETSAPLTVIPATNSESPEEKPMFLHPLKDVTAD 2559

Query: 411  IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLV-LKDLD--KSDSGTYTC 467
                 V        P P++ W  +G  L  + R  VT DG  V L+ L+   SD+G Y+ 
Sbjct: 2560 EGKSLVLSAPFTANPVPMVEWSKDGVPLSPSDRILVTCDGKKVGLEILNAVPSDAGRYSV 2619

Query: 468  VASSRHGKYVWSGALLVDSPINPNIHFFRA-ADVSSLPGPPTK 509
              S+  G+        V     P  HF +   D+  LPG   K
Sbjct: 2620 KISNPLGEESSEANAAVHKVFMPP-HFTQTFTDLQQLPGRDAK 2661



 Score = 98.7 bits (235), Expect = 8e-19
 Identities = 99/342 (28%), Positives = 142/342 (41%), Gaps = 40/342 (11%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGLFF 68
            + P  + +  D  +A +       +  G P+P + ++K GV+V  SD +  I       F
Sbjct: 951  DKPEFVVKLKDTELAENTYLRFMVKVRGDPNPDVIFFKDGVIVEKSDRYEVIREHSDRGF 1010

Query: 69   LRATHGRVH-SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
                   V  SDAG Y C A+N +G   S  ATL V         E   K   +G     
Sbjct: 1011 YELLIPEVQMSDAGEYKCVASNKWGED-SCEATLKVTT-------EDLHKDMPEG----- 1057

Query: 128  ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-----LVIQDARQTDAGRYQCIA 182
            E LPP  +PE    WKK+G    F+ D R  ++ G +     LV Q  R  D G Y C+A
Sbjct: 1058 EILPPGETPE--FQWKKDGAP--FEPDERFKVLMGDDEDSLALVFQHVRAEDVGLYTCVA 1113

Query: 183  RNAAGTRESAIATLKIH----------IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
            + + G   S  A L +H           KP LI    + V   G S   + +V G P P 
Sbjct: 1114 QTSRG-HISCSAELTVHGTVNQLVREPEKPVLIVEKRNPVVNAGGSAMIELQVKGFPKPQ 1172

Query: 233  VLWRRSAGGGNMPLGRVKVLDDG----SLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
            V W    G      G+ K L +     SL + +V   D G+Y C AEN +G+ +A   LT
Sbjct: 1173 VKWTHE-GKPIEAGGKYKFLYEDEETMSLVIKDVQKEDAGKYLCTAENEIGSDTAEMTLT 1231

Query: 289  VYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
            V  PP +      V+  +  +        G P P + +  +G
Sbjct: 1232 VKTPPKLRKKIEDVDAHADLLLEIPVEIEGTPRPKVVFYKDG 1273



 Score = 98.3 bits (234), Expect = 1e-18
 Identities = 122/468 (26%), Positives = 190/468 (40%), Gaps = 39/468 (8%)

Query: 40   SPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS-DAGVYWCEATNSYG-TARSR 97
            +P  +W K G     D    +L       L      V + D G+Y C A  S G  + S 
Sbjct: 1065 TPEFQWKKDGAPFEPDERFKVLMGDDEDSLALVFQHVRAEDVGLYTCVAQTSRGHISCSA 1124

Query: 98   NATLHVAV---LREEFR----LEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
              T+H  V   +RE  +    +E  +     G + ++E L  +G P+P V W   G+ + 
Sbjct: 1125 ELTVHGTVNQLVREPEKPVLIVEKRNPVVNAGGSAMIE-LQVKGFPKPQVKWTHEGKPIE 1183

Query: 151  FDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208
              G  +    D    +LVI+D ++ DAG+Y C A N  G+ ++A  TL +   P L    
Sbjct: 1184 AGGKYKFLYEDEETMSLVIKDVQKEDAGKYLCTAENEIGS-DTAEMTLTVKTPPKLRKKI 1242

Query: 209  EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILA 265
            EDV A     +     + G P P V++ +  G       R+KV+++     L ++  +L 
Sbjct: 1243 EDVDAHADLLLEIPVEIEGTPRPKVVFYKD-GKEIKKDERIKVVEENEKVVLVIEKTMLK 1301

Query: 266  DEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNVESGNVARFTCTATGRPEPT 323
            D G YS  A N +  +S    L V+  P I   L  + + V               PE  
Sbjct: 1302 DSGSYSIVATNELAQISEFFNLHVHTKPKILEKLGKDKI-VSQEEKFELRVKIESEPEAE 1360

Query: 324  MFWSVEGNRTIIFPGMSRDKYHATAVFDGVT-VLTINDTDKNDSRNTIVCSAVNYAGSSF 382
            + W  +           +   H     DG T +L I      D+    V  AVN  GS  
Sbjct: 1361 VKWYKDDAEI-------KSSDHYVIKKDGETYILKITGAVTTDAARYKV-KAVNIHGS-- 1410

Query: 383  VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI-CTPEPIIAWYFEGEALIQN 441
            V   + V   D +  P IT G  + T+      V     +   P+P + WY +   + + 
Sbjct: 1411 VEDDIRV---DVKKAPKITKGLQDMTVNEHDKQVTLDVKVEAFPKPSVKWYLDEMEITET 1467

Query: 442  HR---RNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485
                 R  ++DG  LV+K+++   SG YTC  S+  G    S  L V+
Sbjct: 1468 KTEFTRVDSDDGVKLVIKEVNSELSGKYTCKLSNECGSTETSAKLTVN 1515



 Score = 94.7 bits (225), Expect = 1e-17
 Identities = 116/485 (23%), Positives = 184/485 (37%), Gaps = 35/485 (7%)

Query: 23   VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
            V   +P  L  +  GSP P + WYK G  +  +  ++ +   G   L   H R  SD+G 
Sbjct: 2260 VIEGEPLELKAKINGSPKPTVVWYKNGEPIDDERVKTSVLPDGTVKLNIEHAR-PSDSGA 2318

Query: 83   YWCEATNSYGTARSRNA-TLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVY 141
            Y     N  G +    A  +     R +F    +  +   G+T+ LE    +  P P V 
Sbjct: 2319 YKLVIQNPNGESACLCAVAVQQKPQRPKFLKCFKDVKLPIGETLRLEA-QVQAHPPPEVK 2377

Query: 142  WKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTR--ESAIATLK 197
            W K+G  +    +    +   G   L++  A+  +AG+Y+    N  G    E+++   K
Sbjct: 2378 WIKDGVPVRVSSNIHFEVHPDGKVALIVDCAKPENAGKYELQVSNKYGDAMGEASVEIEK 2437

Query: 198  IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDG 255
               KP  +          G  V F+ +  G P P + W R+          VK+  L DG
Sbjct: 2438 KPTKPEFLVRLVPQTVVEGFPVKFEVKAVGHPAPKLTWSRNGAEVISDNKHVKISELPDG 2497

Query: 256  S--LRLDNVILADEG-EYSCEAENSVGAVSASGYLTVYDPPSINLSP----------NSV 302
            +  L LD    A +G  Y   A N  G    S  LTV  P + + SP            V
Sbjct: 2498 TSVLLLDAANQARDGLTYRAIAINEAGEAETSAPLTVI-PATNSESPEEKPMFLHPLKDV 2556

Query: 303  NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
              + G     +   T  P P + WS +G      P    D+   T     V +  +N   
Sbjct: 2557 TADEGKSLVLSAPFTANPVPMVEWSKDG-----VPLSPSDRILVTCDGKKVGLEILNAVP 2611

Query: 363  KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
             +  R ++  S  N  G         V      PP         Q LP +  A FPC   
Sbjct: 2612 SDAGRYSVKIS--NPLGEESSEANAAV-HKVFMPPHFTQTFTDLQQLPGRD-AKFPCRVS 2667

Query: 423  CTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGKYVWS 479
              P+P + W  +G  + ++ + ++  DG    L + +    D+  Y   A ++ G+ V +
Sbjct: 2668 GVPQPEVVWTKDGLPIKESDKYHIKRDGDLCCLYVLNCSPDDAAVYRARAINKEGEEVCT 2727

Query: 480  GALLV 484
             +L V
Sbjct: 2728 ASLEV 2732



 Score = 88.6 bits (210), Expect = 9e-16
 Identities = 73/288 (25%), Positives = 130/288 (45%), Gaps = 14/288 (4%)

Query: 12   PYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
            P I+E+   D  V++ +   L  +    P   ++WYK    + S  H  I   G  + L+
Sbjct: 1329 PKILEKLGKDKIVSQEEKFELRVKIESEPEAEVKWYKDDAEIKSSDHYVIKKDGETYILK 1388

Query: 71   ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
             T G V +DA  Y  +A N +G+    +  + V    +  +   +   +     V L+ +
Sbjct: 1389 IT-GAVTTDAARYKVKAVNIHGSVED-DIRVDVKKAPKITKGLQDMTVNEHDKQVTLD-V 1445

Query: 131  PPRGSPEPNVYWKKNGQTLLFDGD--SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
                 P+P+V W  +   +       +R+   DG  LVI++     +G+Y C   N  G+
Sbjct: 1446 KVEAFPKPSVKWYLDEMEITETKTEFTRVDSDDGVKLVIKEVNSELSGKYTCKLSNECGS 1505

Query: 189  RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
             E++ A L ++  P +I   +D   + G+++  +  V G P P V W R+ G       R
Sbjct: 1506 TETS-AKLTVNCAPRIIKQLKDTTVEEGATLHLEVEVEGCPTPTVKWLRN-GREVSADAR 1563

Query: 249  VKVLDDG------SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290
            +K+  D       +L ++ +   +EGEY     NS+G VS+  Y+TV+
Sbjct: 1564 IKISRDTQRHETFNLAVNLIKYEEEGEYEVVVTNSMGTVSSKSYVTVH 1611



 Score = 88.6 bits (210), Expect = 9e-16
 Identities = 102/426 (23%), Positives = 177/426 (41%), Gaps = 47/426 (11%)

Query: 135  SPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIARNAAG-TRE 190
            +P P   W  NGQ L    DSR+ + + G    L I   +  DAG+ +CI +N  G  R+
Sbjct: 1878 NPPPKATWTINGQEL--KPDSRVRMTNKGEEFKLEIVKLKMDDAGKIECILKNPLGEARQ 1935

Query: 191  SAIATL---KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM--- 244
            +A+  +   K   +P L  G +D   Q  +++TF+  V GDP+PD  W  S  G  +   
Sbjct: 1936 TAMLEVTPEKELRRPKLKEGLKDQTIQKKNTLTFKAVVIGDPVPDATW--SVDGHELTSE 1993

Query: 245  PLGRVKV--------LDDG------SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290
               + K+        + DG      +L +      + G+Y+  A+N  G  ++S  LTV 
Sbjct: 1994 AFEKYKIILETEDHEIQDGLKECTYTLTIPRCERCNAGKYTFFAKNKWGECNSSAQLTVV 2053

Query: 291  DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
              P I   P +V+V  G      C     P+  + W+ +     +       K  +    
Sbjct: 2054 LRPEIE-GPQNVSVIPGEATELVCKIQANPQAEVHWTKDDQ---VVKETENLKIVSDVAN 2109

Query: 351  DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
            +   ++       ++    +V  A N  G S    +L   ++    P IIT    +Q   
Sbjct: 2110 ETYRLVFKKALLSDEGYYKVV--AKNSLGESSSEARLKAVTE---KPTIITGLSDDQVEH 2164

Query: 411  IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN------DGTLVLKDLDKSDSGT 464
             K ++V    A   P+P I W   G+ ++++ +  + +        TL + D + SDSG 
Sbjct: 2165 TKEISVM-VRADGLPKPQIRWLLNGKPIVEDEKHKIESHADAQVTSTLTVSDFNDSDSGI 2223

Query: 465  YTCVASSRHGKYVWSGAL-LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLS 523
            Y  +A++  G+   S  + +V +P        R+ DV  + G P +           T+ 
Sbjct: 2224 YKAIAANVQGEADTSARITMVQTPPTFGKKLERSEDV--IEGEPLELKAKINGSPKPTVV 2281

Query: 524  WSQNNK 529
            W +N +
Sbjct: 2282 WYKNGE 2287



 Score = 87.4 bits (207), Expect = 2e-15
 Identities = 107/404 (26%), Positives = 152/404 (37%), Gaps = 36/404 (8%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR---SILPAGGLFF 68
            P  + + +  TV    P     +A G P+P + W + G  V+SD      S LP G    
Sbjct: 2442 PEFLVRLVPQTVVEGFPVKFEVKAVGHPAPKLTWSRNGAEVISDNKHVKISELPDGTSVL 2501

Query: 69   LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE------FRLEPESKQSA-Q 121
            L     +   D   Y   A N  G A +      +     E        L P    +A +
Sbjct: 2502 LLDAANQAR-DGLTYRAIAINEAGEAETSAPLTVIPATNSESPEEKPMFLHPLKDVTADE 2560

Query: 122  GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQ 179
            G ++VL   P   +P P V W K+G  L    D  +   DG    L I +A  +DAGRY 
Sbjct: 2561 GKSLVLSA-PFTANPVPMVEWSKDGVPLS-PSDRILVTCDGKKVGLEILNAVPSDAGRYS 2618

Query: 180  CIARNAAG--TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
                N  G  + E+  A  K+ + P+      D+    G    F CRV G P P+V+W +
Sbjct: 2619 VKISNPLGEESSEANAAVHKVFMPPHFTQTFTDLQQLPGRDAKFPCRVSGVPQPEVVWTK 2678

Query: 238  SAGGGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--- 291
              G       +  +  DG    L + N    D   Y   A N  G    +  L V D   
Sbjct: 2679 D-GLPIKESDKYHIKRDGDLCCLYVLNCSPDDAAVYRARAINKEGEEVCTASLEVVDQIQ 2737

Query: 292  ------PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345
                  PP+         +  G  A+FT  A+G PEP + W    N   +FP  +R K  
Sbjct: 2738 AKKKIEPPTFLKRIGDTELFKGMTAKFTACASGYPEPEVEW--YHNDQKLFPS-NRIKME 2794

Query: 346  ATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389
                 +G+  L I+D D+ D      C   N  G       L +
Sbjct: 2795 TDP--NGLLRLIISDLDEAD-LGKYSCKITNEYGGDICHANLNM 2835



 Score = 81.0 bits (191), Expect = 2e-13
 Identities = 107/466 (22%), Positives = 177/466 (37%), Gaps = 33/466 (7%)

Query: 79   DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
            +AG Y   A N +G   S +A L V VLR E    P++     G+   L C   + +P+ 
Sbjct: 2029 NAGKYTFFAKNKWGECNS-SAQLTV-VLRPEIE-GPQNVSVIPGEATELVC-KIQANPQA 2084

Query: 139  NVYWKKNGQTLLFDGDSRMHLVDGGN----LVIQDARQTDAGRYQCIARNAAGTRESAIA 194
             V+W K+ Q +  + ++   + D  N    LV + A  +D G Y+ +A+N+ G   S   
Sbjct: 2085 EVHWTKDDQVVK-ETENLKIVSDVANETYRLVFKKALLSDEGYYKVVAKNSLGESSSEAR 2143

Query: 195  TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254
               +  KP +ITG  D   +    ++   R  G P P + W  + G   +   + K+   
Sbjct: 2144 LKAVTEKPTIITGLSDDQVEHTKEISVMVRADGLPKPQIRWLLN-GKPIVEDEKHKIESH 2202

Query: 255  GSLRLDNVIL------ADEGEYSCEAENSVGAVSASGYLT-VYDPPSINLS-PNSVNVES 306
               ++ + +       +D G Y   A N  G    S  +T V  PP+       S +V  
Sbjct: 2203 ADAQVTSTLTVSDFNDSDSGIYKAIAANVQGEADTSARITMVQTPPTFGKKLERSEDVIE 2262

Query: 307  GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
            G          G P+PT+ W   G        +  ++   + + DG   L I     +DS
Sbjct: 2263 GEPLELKAKINGSPKPTVVWYKNGE------PIDDERVKTSVLPDGTVKLNIEHARPSDS 2316

Query: 367  RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
                     N  G S     + V     RP         +  LPI             P 
Sbjct: 2317 -GAYKLVIQNPNGESACLCAVAVQQKPQRPK--FLKCFKDVKLPIGETLRLEAQVQAHPP 2373

Query: 427  PIIAWYFEG--EALIQNHRRNVTNDG--TLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482
            P + W  +G    +  N    V  DG   L++      ++G Y    S+++G  +   ++
Sbjct: 2374 PEVKWIKDGVPVRVSSNIHFEVHPDGKVALIVDCAKPENAGKYELQVSNKYGDAMGEASV 2433

Query: 483  LVD-SPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527
             ++  P  P     R    + + G P K     V   +  L+WS+N
Sbjct: 2434 EIEKKPTKPEF-LVRLVPQTVVEGFPVKFEVKAVGHPAPKLTWSRN 2478



 Score = 68.9 bits (161), Expect = 8e-10
 Identities = 76/300 (25%), Positives = 110/300 (36%), Gaps = 11/300 (3%)

Query: 37   GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
            G+P P + +YK G  +  D    ++       L      +  D+G Y   ATN      S
Sbjct: 1261 GTPRPKVVFYKDGKEIKKDERIKVVEENEKVVL-VIEKTMLKDSGSYSIVATNELAQI-S 1318

Query: 97   RNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSR 156
                LHV    +      + K  +Q +   L  +     PE  V W K+   +    D  
Sbjct: 1319 EFFNLHVHTKPKILEKLGKDKIVSQEEKFELR-VKIESEPEAEVKWYKDDAEIK-SSDHY 1376

Query: 157  MHLVDGGNLVIQ--DARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDV-VA 213
            +   DG   +++   A  TDA RY+  A N  G+ E  I  + +   P +  G +D+ V 
Sbjct: 1377 VIKKDGETYILKITGAVTTDAARYKVKAVNIHGSVEDDIR-VDVKKAPKITKGLQDMTVN 1435

Query: 214  QTGSSVTFQCRVGGDPLPDVLW---RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEY 270
            +    VT   +V   P P V W               RV   D   L +  V     G+Y
Sbjct: 1436 EHDKQVTLDVKVEAFPKPSVKWYLDEMEITETKTEFTRVDSDDGVKLVIKEVNSELSGKY 1495

Query: 271  SCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
            +C+  N  G+   S  LTV   P I        VE G          G P PT+ W   G
Sbjct: 1496 TCKLSNECGSTETSAKLTVNCAPRIIKQLKDTTVEEGATLHLEVEVEGCPTPTVKWLRNG 1555



 Score = 64.1 bits (149), Expect = 2e-08
 Identities = 92/453 (20%), Positives = 161/453 (35%), Gaps = 28/453 (6%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
            V   E P +I +  +  V     A +  +  G P P ++W   G  + +      L    
Sbjct: 1136 VREPEKPVLIVEKRNPVVNAGGSAMIELQVKGFPKPQVKWTHEGKPIEAGGKYKFLYEDE 1195

Query: 66   LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
                         DAG Y C A N  G   S  A + + V       +      A  D +
Sbjct: 1196 ETMSLVIKDVQKEDAGKYLCTAENEIG---SDTAEMTLTVKTPPKLRKKIEDVDAHADLL 1252

Query: 126  VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIA 182
            +   +   G+P P V + K+G+ +    D R+ +V+      LVI+     D+G Y  +A
Sbjct: 1253 LEIPVEIEGTPRPKVVFYKDGKEI--KKDERIKVVEENEKVVLVIEKTMLKDSGSYSIVA 1310

Query: 183  RNAAGTRESAIATLKIHIKPYLI--TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
             N    + S    L +H KP ++   G + +V+Q       + ++  +P  +V W +   
Sbjct: 1311 TNEL-AQISEFFNLHVHTKPKILEKLGKDKIVSQE-EKFELRVKIESEPEAEVKWYKD-D 1367

Query: 241  GGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
                      +  DG    L++   +  D   Y  +A N  G+V     + V   P I  
Sbjct: 1368 AEIKSSDHYVIKKDGETYILKITGAVTTDAARYKVKAVNIHGSVEDDIRVDVKKAPKITK 1427

Query: 298  SPNSVNV-ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
                + V E              P+P++ W ++          ++ ++      DGV  L
Sbjct: 1428 GLQDMTVNEHDKQVTLDVKVEAFPKPSVKWYLDEMEIT----ETKTEFTRVDSDDGVK-L 1482

Query: 357  TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416
             I + + ++      C   N  GS+    KLTV        P I     + T+   +   
Sbjct: 1483 VIKEVN-SELSGKYTCKLSNECGSTETSAKLTVNC-----APRIIKQLKDTTVEEGATLH 1536

Query: 417  FPCTAICTPEPIIAWYFEGEALIQNHRRNVTND 449
                    P P + W   G  +  + R  ++ D
Sbjct: 1537 LEVEVEGCPTPTVKWLRNGREVSADARIKISRD 1569



 Score = 60.5 bits (140), Expect = 3e-07
 Identities = 50/165 (30%), Positives = 71/165 (43%), Gaps = 14/165 (8%)

Query: 134  GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRES 191
            G P+P V +  N + +   G   M     G   L I    + D G Y+ +A N  G    
Sbjct: 3028 GYPKPKVSFYFNDELIESGGRFDMSYTRNGQATLFINKMLERDVGWYEAVATNEHGEARQ 3087

Query: 192  AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---R 248
             +  L+I   P  I  PE   A     V F  R+ G P P++ W +       PL    R
Sbjct: 3088 RVR-LEIAEMPQFIRRPEIQYAMHRGKVRFDARIVGVPYPEIKWYKDW----KPLAASTR 3142

Query: 249  VKVL----DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
            +KV     D   L ++++I  DEG YS  A N  G++S+S  L V
Sbjct: 3143 IKVSSFFPDTAVLVINDIITKDEGLYSVSARNVAGSISSSAMLHV 3187



 Score = 44.4 bits (100), Expect = 0.019
 Identities = 51/198 (25%), Positives = 76/198 (38%), Gaps = 7/198 (3%)

Query: 10   EAPYIIEQPLDVTVA-RHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
            +AP  + Q  D     + Q   L     G P P + +Y    L+ S     +        
Sbjct: 3000 QAPRFLRQEHDTQYGVKDQNTNLFWFVYGYPKPKVSFYFNDELIESGGRFDMSYTRNGQA 3059

Query: 69   LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
                +  +  D G Y   ATN +G AR R   L +A +  +F   PE + +     V  +
Sbjct: 3060 TLFINKMLERDVGWYEAVATNEHGEARQR-VRLEIAEM-PQFIRRPEIQYAMHRGKVRFD 3117

Query: 129  CLPPRGSPEPNVYWKKNGQTLLFDGDSRM--HLVDGGNLVIQDARQTDAGRYQCIARNAA 186
                 G P P + W K+ + L      ++     D   LVI D    D G Y   ARN A
Sbjct: 3118 ARIV-GVPYPEIKWYKDWKPLAASTRIKVSSFFPDTAVLVINDIITKDEGLYSVSARNVA 3176

Query: 187  GT-RESAIATLKIHIKPY 203
            G+   SA+  ++ H   Y
Sbjct: 3177 GSISSSAMLHVEEHDHDY 3194



 Score = 41.1 bits (92), Expect = 0.18
 Identities = 32/118 (27%), Positives = 48/118 (40%), Gaps = 3/118 (2%)

Query: 11   APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL--PAGGLFF 68
            AP II+Q  D TV       L     G P+P ++W + G  V +D    I         F
Sbjct: 1517 APRIIKQLKDTTVEEGATLHLEVEVEGCPTPTVKWLRNGREVSADARIKISRDTQRHETF 1576

Query: 69   LRATHGRVHSDAGVYWCEATNSYGTARSRN-ATLHVAVLREEFRLEPESKQSAQGDTV 125
              A +   + + G Y    TNS GT  S++  T+H     +   +E E     + + V
Sbjct: 1577 NLAVNLIKYEEEGEYEVVVTNSMGTVSSKSYVTVHKVTHTDAIEVEEEPPMQLKVEVV 1634



 Score = 40.3 bits (90), Expect = 0.31
 Identities = 25/95 (26%), Positives = 41/95 (43%), Gaps = 10/95 (10%)

Query: 502  SLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV 561
            S P  P  P +   +DT + L+W Q    G+S +L Y +E    + +           W 
Sbjct: 3627 STPEEPDSPESDQSSDTEIFLTWKQPRFDGNSPVLCYSLEYKLADDIE----------WT 3676

Query: 562  VIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
              A  +    Y+++ L P  +YMF +   N+ G S
Sbjct: 3677 KKADNIDHEFYLMRGLTPSSSYMFRLAARNAIGWS 3711


>UniRef50_Q2VWP7 Cluster: Protogenin homolog; n=32;
           Euteleostomi|Rep: Protogenin homolog - Homo sapiens
           (Human)
          Length = 1150

 Score =  157 bits (380), Expect = 2e-36
 Identities = 136/475 (28%), Positives = 209/475 (44%), Gaps = 41/475 (8%)

Query: 15  IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74
           +++P DVTV R  P  L+C+A G     + W K G  +  +    +L  G L ++    G
Sbjct: 42  VKEPQDVTVTRKDPVVLDCQAHGEVPIKVTWLKNGAKMSENKRIEVLSNGSL-YISEVEG 100

Query: 75  R--VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP 132
           R    SD G Y C A N YG   S+ A L ++ +   F ++P S +  +G      C   
Sbjct: 101 RRGEQSDEGFYQCLAMNKYGAILSQKAHLALSTI-SAFEVQPISTEVHEGGVARFAC-KI 158

Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
              P   + W+ N  TL    D R+  +  G L I D  Q D+G Y+CIA   A  R+S 
Sbjct: 159 SSHPPAVITWEFNRTTLPMTMD-RITALPTGVLQIYDVSQRDSGNYRCIAATVAHRRKSM 217

Query: 193 IATL--------KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
            A+L        K    P +I GP+++      +V  +C   G+P P + W R     ++
Sbjct: 218 EASLTVIPAKESKSFHTPTIIAGPQNITTSLHQTVVLECMATGNPKPIISWSR-LDHKSI 276

Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEA--ENSVGAVSASGYLTVYDPPSINLSPNSV 302
            +   +VL +G+L + +V L   G Y C A    +     A   LTV  PPS    P S+
Sbjct: 277 DVFNTRVLGNGNLMISDVRLQHAGVYVCRATTPGTRNFTVAMATLTVLAPPSFVEWPESL 336

Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
                  ARF C A G P P M W ++  R I   G  +  Y++         L IN   
Sbjct: 337 TRPRAGTARFVCQAEGIPSPKMSW-LKNGRKIHSNGRIK-MYNSK--------LVINQII 386

Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN---QTLPIKSMAVFPC 419
             D      C A N  GS   R +LTV   +DRP     + P N   +T+   ++ +   
Sbjct: 387 PEDDA-IYQCMAENSQGSILSRARLTVVMSEDRP-----SAPYNVHAETMSSSAILLAWE 440

Query: 420 TAICTPEPIIAW---YFEGEAL-IQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVA 469
             +   + +IA+   Y + E L  + ++  + ND T  ++ DL+ + + T+  VA
Sbjct: 441 RPLYNSDKVIAYSVHYMKAEGLNNEEYQVVIGNDTTHYIIDDLEPASNYTFYIVA 495



 Score =  117 bits (281), Expect = 2e-24
 Identities = 125/511 (24%), Positives = 191/511 (37%), Gaps = 56/511 (10%)

Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
           F  EP+     + D VVL+C    G     V W KNG  +    + R+ ++  G+L I +
Sbjct: 41  FVKEPQDVTVTRKDPVVLDC-QAHGEVPIKVTWLKNGAKM--SENKRIEVLSNGSLYISE 97

Query: 170 AR-----QTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR 224
                  Q+D G YQC+A N  G   S  A L +         P       G    F C+
Sbjct: 98  VEGRRGEQSDEGFYQCLAMNKYGAILSQKAHLALSTISAFEVQPISTEVHEGGVARFACK 157

Query: 225 VGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAEN-SVGAVSA 283
           +   P   + W  +     M + R+  L  G L++ +V   D G Y C A   +    S 
Sbjct: 158 ISSHPPAVITWEFNRTTLPMTMDRITALPTGVLQIYDVSQRDSGNYRCIAATVAHRRKSM 217

Query: 284 SGYLTV--------YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII 335
              LTV        +  P+I   P ++           C ATG P+P + WS   +++I 
Sbjct: 218 EASLTVIPAKESKSFHTPTIIAGPQNITTSLHQTVVLECMATGNPKPIISWSRLDHKSI- 276

Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395
                 D ++   + +G   L I+D  +       VC A      +F     T+T     
Sbjct: 277 ------DVFNTRVLGNG--NLMISDV-RLQHAGVYVCRATTPGTRNFTVAMATLTV---L 324

Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLK 455
            PP     P + T P    A F C A   P P ++W   G  +  N R  + N   LV+ 
Sbjct: 325 APPSFVEWPESLTRPRAGTARFVCQAEGIPSPKMSWLKNGRKIHSNGRIKMYN-SKLVIN 383

Query: 456 DLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNV 515
            +   D   Y C+A +  G  +    L V                   P  P       +
Sbjct: 384 QIIPEDDAIYQCMAENSQGSILSRARLTV-------------VMSEDRPSAPYNVHAETM 430

Query: 516 TDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVK 575
           + +++ L+W +     S  ++ Y V     E L+      N    VVI      THY++ 
Sbjct: 431 SSSAILLAW-ERPLYNSDKVIAYSVHYMKAEGLN------NEEYQVVIGN--DTTHYIID 481

Query: 576 SLIPGITYMFIVRTENSHGLSGPSPVSDSVT 606
            L P   Y F +    ++   G S +SD VT
Sbjct: 482 DLEPASNYTFYI---VAYMPMGASQMSDHVT 509



 Score = 77.4 bits (182), Expect = 2e-12
 Identities = 67/214 (31%), Positives = 93/214 (43%), Gaps = 15/214 (7%)

Query: 8   SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
           S   P II  P ++T + HQ   L C A G+P P I W +     +   +  +L  G L 
Sbjct: 231 SFHTPTIIAGPQNITTSLHQTVVLECMATGNPKPIISWSRLDHKSIDVFNTRVLGNGNLM 290

Query: 68  F--LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDT 124
              +R  H      AGVY C AT   GT     A   + VL     +E PES    +  T
Sbjct: 291 ISDVRLQH------AGVYVCRATTP-GTRNFTVAMATLTVLAPPSFVEWPESLTRPRAGT 343

Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
               C    G P P + W KNG+ +  +G  +M+      LVI      D   YQC+A N
Sbjct: 344 ARFVC-QAEGIPSPKMSWLKNGRKIHSNGRIKMY---NSKLVINQIIPEDDAIYQCMAEN 399

Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSS 218
           + G+  S  A L + +     + P +V A+T SS
Sbjct: 400 SQGSILSR-ARLTVVMSEDRPSAPYNVHAETMSS 432



 Score = 53.2 bits (122), Expect = 4e-05
 Identities = 37/136 (27%), Positives = 63/136 (46%), Gaps = 11/136 (8%)

Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
           +  L   TKYEF +     +     S      TL + P GPP+ +++ ++   T  + W 
Sbjct: 782 VQGLEPNTKYEFAVRLHVDQLSSPWSPVVYHSTLPEAPAGPPVGVKVTLIEDDTALVSWK 841

Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTV-HQ---ATSLIMTNLTSGVSYSVQ 809
           PP+      ++T Y ++       + K+ +A    V H+    T  ++ NL +G  Y V+
Sbjct: 842 PPD--GPETVVTRYTIL-----YASRKAWIAGEWQVLHREGAITMALLENLVAGNVYIVK 894

Query: 810 IAAETIIGLGPFSQKV 825
           I+A   +G GPFS  V
Sbjct: 895 ISASNEVGEGPFSNSV 910



 Score = 51.2 bits (117), Expect = 2e-04
 Identities = 42/186 (22%), Positives = 81/186 (43%), Gaps = 9/186 (4%)

Query: 639 IEATPIDSKTIKLMWE--ILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITS 696
           + A  + S  I L WE  + N   +    +++   + +  E E + ++  ND + + I  
Sbjct: 425 VHAETMSSSAILLAWERPLYNSDKVIAYSVHYMKAEGLNNE-EYQVVI-GNDTTHYIIDD 482

Query: 697 LRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPE 756
           L   + Y F+++ +      + S+     TL+DVP  PP  I +   + T + + W P  
Sbjct: 483 LEPASNYTFYIVAYMPMGASQMSDHVTQNTLEDVPLRPP-EISLTSRSPTDILISWLPIP 541

Query: 757 LQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETII 816
            + + G +  Y +    L    +  ++ +  T H+    ++  L     Y V+I A T +
Sbjct: 542 AKYRRGQVVLYRLSFR-LSTENSIQVLELPGTTHE---YLLEGLKPDSVYLVRITAATRV 597

Query: 817 GLGPFS 822
           GLG  S
Sbjct: 598 GLGESS 603


>UniRef50_Q6WRI0 Cluster: Immunoglobulin superfamily member 10
            precursor; n=20; Mammalia|Rep: Immunoglobulin superfamily
            member 10 precursor - Homo sapiens (Human)
          Length = 2623

 Score =  156 bits (378), Expect = 4e-36
 Identities = 144/502 (28%), Positives = 222/502 (44%), Gaps = 56/502 (11%)

Query: 12   PYIIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTH----RSILPAGGL 66
            P I+EQ   V V    +   L C A G+P P++ W       V        +  L + G 
Sbjct: 1842 PVILEQRRQVIVGTWGESLKLPCTAKGTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSNGT 1901

Query: 67   FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GD 123
             ++R       SD G Y C AT+S G+ R R   L +       R+E  S++  +   GD
Sbjct: 1902 LYIR---NLASSDRGTYECIATSSTGSER-RVVMLTMEERVTSPRIEAASQKRTEVNFGD 1957

Query: 124  TVVLECLPPRGSPEPNVYWKKNGQTLLFDGD---SRMHLVDGGNLVIQDARQTDAGRYQC 180
             ++L C    G P+P + W+   + ++       S +H+   G+L I    + D+G Y C
Sbjct: 1958 KLLLNC-SATGEPKPQIMWRLPSKAVVDQQHRVGSWIHVYPNGSLFIGSVTEKDSGVYLC 2016

Query: 181  IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQ--CRVGGDPLPDVLWR-- 236
            +ARN  G  +  +  + + +KP  I   +    Q      FQ  C+  G P+P++ W   
Sbjct: 2017 VARNKMGD-DLILMHVSLRLKPAKIDHKQYFRKQVLHGKDFQVDCKASGSPVPEISWSLP 2075

Query: 237  --------RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
                      A        R  + ++G+L  + V +A+EG+Y+C A+N++G      +LT
Sbjct: 2076 DGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKDEMKVHLT 2135

Query: 289  VYDP-PSINLSPNSVN--VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345
            V    P I  S N  N  +++G+ A   C  TG P+P +FW +  N  I F  + R  +H
Sbjct: 2136 VITAAPRIRQS-NKTNKRIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISF-SIDRYTFH 2193

Query: 346  ATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPS 405
            A         LTIN     DS    VC A N +G      KL V S     PP+I    +
Sbjct: 2194 ANGS------LTINKVKLLDS-GEYVCVARNPSGDDTKMYKLDVVSK----PPLINGLYT 2242

Query: 406  NQTLPIKSMAV------FPCTAICTPEPIIAWYFEGEALIQ----NHRRNVTNDGTLVLK 455
            N+T+ IK+ AV      F C A  TP P + W       +       R  V  +GTL ++
Sbjct: 2243 NRTV-IKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIR 2301

Query: 456  DLDKSDSGTYTCVASSRHGKYV 477
            ++  SDS  + CVA +  G+ V
Sbjct: 2302 NVRLSDSADFICVARNEGGESV 2323



 Score =  126 bits (304), Expect = 4e-27
 Identities = 102/375 (27%), Positives = 165/375 (44%), Gaps = 17/375 (4%)

Query: 19   LDVTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
            +  T  RH     +CRA G+PSP + W     + + +  + S +       L   + R+ 
Sbjct: 2247 IKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRL- 2305

Query: 78   SDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQ-GDTVVLECLPPRGS 135
            SD+  + C A N  G +        + +LR   FR     K  AQ G +  L C    G+
Sbjct: 2306 SDSADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGKSTALNC-SVDGN 2364

Query: 136  PEPNVYW-KKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
            P P + W   NG        S  +L+   G+ +I    + DAG+Y+C ARN  G  E  +
Sbjct: 2365 PPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEK-L 2423

Query: 194  ATLKIHIKPYLIT-GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG-GGNMPL--GRV 249
              L+I  KP ++T  P  V   +G S++  C   G P P++ W   +G   + P   G+ 
Sbjct: 2424 VILEIGQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKY 2483

Query: 250  KVLDDGSLRLDNVILADEGEYSCEAENSVG--AVSASGYLTVYDPPSINLSPNSVNVESG 307
             + D+G+L +      D G Y C+A+NSVG   ++    +  Y P   N  P S+   +G
Sbjct: 2484 ILHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPRITNRPPRSIVTRTG 2543

Query: 308  NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
               +  C A G P+P + W +  +   +    S+++ H +        L I +   +DS 
Sbjct: 2544 AAFQLHCVALGVPKPEITWEMPDHS--LLSTASKERTHGSEQLHLQGTLVIQNPQTSDS- 2600

Query: 368  NTIVCSAVNYAGSSF 382
                C+A N  GS +
Sbjct: 2601 GIYKCTAKNPLGSDY 2615



 Score =  125 bits (301), Expect = 8e-27
 Identities = 141/501 (28%), Positives = 201/501 (40%), Gaps = 54/501 (10%)

Query: 10   EAPYIIE-QPLDVTVARHQPATLNCRAGGSPSPAIRWYK--GGVLVVSDTHRS---ILPA 63
            E P I+  +    T+  +  A L C A G+P P I W +   G+ +      S   +LP 
Sbjct: 1646 EKPRIVGGKAASFTIPANSDAFLPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPN 1705

Query: 64   GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA--Q 121
            G L   R        D G Y C A+N +GT    + TL V        LE  +K+     
Sbjct: 1706 GTLSIQRVE----IQDRGQYLCSASNLFGTDH-LHVTLSVVSYPPRI-LERRTKEITVHS 1759

Query: 122  GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGD--SRMHLVD-GGNLVIQDARQTDAGRY 178
            G TV L+C    G P P V W    QT++ +    SR  +V   G LV+ +    D G Y
Sbjct: 1760 GSTVELKC-RAEGRPSPTVTWILANQTVVSESSQGSRQAVVTVDGTLVLHNLSIYDRGFY 1818

Query: 179  QCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRR 237
            +C+A N  G     +    I   P ++     V+  T G S+   C   G P P V W  
Sbjct: 1819 KCVASNPGGQDSLLVKIQVIAAPPVILEQRRQVIVGTWGESLKLPCTAKGTPQPSVYWVL 1878

Query: 238  SAGGGNMPL----GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-- 291
            S G    PL     ++ +  +G+L + N+  +D G Y C A +S G+      LT+ +  
Sbjct: 1879 SDGTEVKPLQFTNSKLFLFSNGTLYIRNLASSDRGTYECIATSSTGSERRVVMLTMEERV 1938

Query: 292  -PPSIN-LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
              P I   S     V  G+     C+ATG P+P + W +     +       D+ H    
Sbjct: 1939 TSPRIEAASQKRTEVNFGDKLLLNCSATGEPKPQIMWRLPSKAVV-------DQQHRVGS 1991

Query: 350  FDGV---TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP-S 405
            +  V     L I    + DS    +C A N  G   +   L   S   +P  I       
Sbjct: 1992 WIHVYPNGSLFIGSVTEKDS-GVYLCVARNKMGDDLI---LMHVSLRLKPAKIDHKQYFR 2047

Query: 406  NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN--------HR-RNVT--NDGTLVL 454
             Q L  K   V  C A  +P P I+W      +I N        HR R  T  N+GTL  
Sbjct: 2048 KQVLHGKDFQV-DCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYF 2106

Query: 455  KDLDKSDSGTYTCVASSRHGK 475
              +  ++ G YTC A +  GK
Sbjct: 2107 NKVGVAEEGDYTCYAQNTLGK 2127



 Score =  125 bits (301), Expect = 8e-27
 Identities = 124/489 (25%), Positives = 205/489 (41%), Gaps = 39/489 (7%)

Query: 12   PYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD----THRSILPAGGL 66
            P I+E+   ++TV       L CRA G PSP + W      VVS+    + ++++   G 
Sbjct: 1745 PRILERRTKEITVHSGSTVELKCRAEGRPSPTVTWILANQTVVSESSQGSRQAVVTVDGT 1804

Query: 67   FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ---SAQGD 123
              L   H     D G Y C A+N  G     +  + + V+     +  + +Q      G+
Sbjct: 1805 LVL---HNLSIYDRGFYKCVASNPGG---QDSLLVKIQVIAAPPVILEQRRQVIVGTWGE 1858

Query: 124  TVVLECLPPRGSPEPNVYWKKNGQT----LLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179
            ++ L C   +G+P+P+VYW  +  T    L F  +S++ L   G L I++   +D G Y+
Sbjct: 1859 SLKLPC-TAKGTPQPSVYWVLSDGTEVKPLQFT-NSKLFLFSNGTLYIRNLASSDRGTYE 1916

Query: 180  CIARNAAGT-RESAIATLKIHIKPYLITGPEDVVAQT--GSSVTFQCRVGGDPLPDVLWR 236
            CIA ++ G+ R   + T++  +    I        +   G  +   C   G+P P ++WR
Sbjct: 1917 CIATSSTGSERRVVMLTMEERVTSPRIEAASQKRTEVNFGDKLLLNCSATGEPKPQIMWR 1976

Query: 237  ---RSAGGGNMPLGR-VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV-YD 291
               ++       +G  + V  +GSL + +V   D G Y C A N +G      ++++   
Sbjct: 1977 LPSKAVVDQQHRVGSWIHVYPNGSLFIGSVTEKDSGVYLCVARNKMGDDLILMHVSLRLK 2036

Query: 292  PPSINLSPN-SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT--- 347
            P  I+        V  G   +  C A+G P P + WS+     I     + D  H T   
Sbjct: 2037 PAKIDHKQYFRKQVLHGKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRY 2096

Query: 348  AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407
             +F+  T L  N     +      C A N  G   ++  LTV +     P I  +  +N+
Sbjct: 2097 TLFNNGT-LYFNKVGVAE-EGDYTCYAQNTLGKDEMKVHLTVIT---AAPRIRQSNKTNK 2151

Query: 408  TLPIKSMAVFPCTAICTPEPIIAWYFEGEALI--QNHRRNVTNDGTLVLKDLDKSDSGTY 465
             +     AV  C     P+P I W      +I     R     +G+L +  +   DSG Y
Sbjct: 2152 RIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVKLLDSGEY 2211

Query: 466  TCVASSRHG 474
             CVA +  G
Sbjct: 2212 VCVARNPSG 2220



 Score =  120 bits (288), Expect = 3e-25
 Identities = 120/469 (25%), Positives = 189/469 (40%), Gaps = 38/469 (8%)

Query: 29   ATLNCRAGGSPSPAIRWYKGGVLVVS-DTHRSILPAGGLFFLRATHGRVHSDAGVYWCEA 87
            A L+C   G P P I W      ++S    R    A G   +         D+G Y C A
Sbjct: 2159 AVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVK---LLDSGEYVCVA 2215

Query: 88   TNSYGTARSR---NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK 144
             N  G        +      ++   +      K +A   +         G+P P V W  
Sbjct: 2216 RNPSGDDTKMYKLDVVSKPPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIM 2275

Query: 145  NGQTLLFDG--DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA--TLKIHI 200
                 L      SR+ +   G L I++ R +D+  + C+ARN  G     +    L++  
Sbjct: 2276 PDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLR 2335

Query: 201  KPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPLG-RVKVLDDG 255
            +P     P  E +VAQ G S    C V G+P P+++W    G    N P   +  +  +G
Sbjct: 2336 RP-TFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNG 2394

Query: 256  SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-NLSPNSVNVESGNVARFTC 314
            S  +      D G+Y C A N VG +     L +   P I   +P +V   SG      C
Sbjct: 2395 SFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQKPVILTYAPGTVKGISGESLSLHC 2454

Query: 315  TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
             + G P+P + W++     +  P ++  KY    + D  T L I +    D R   +C A
Sbjct: 2455 VSDGIPKPNIKWTMPSGYVVDRPQIN-GKY---ILHDNGT-LVIKEATAYD-RGNYICKA 2508

Query: 375  VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP--CTAICTPEPIIAWY 432
             N  G + +   + + +     PP ITN P  +++  ++ A F   C A+  P+P I W 
Sbjct: 2509 QNSVGHTLITVPVMIVAY----PPRITNRPP-RSIVTRTGAAFQLHCVALGVPKPEITWE 2563

Query: 433  FEGEALIQNHRRNVTN-------DGTLVLKDLDKSDSGTYTCVASSRHG 474
                +L+    +  T+        GTLV+++   SDSG Y C A +  G
Sbjct: 2564 MPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLG 2612



 Score =  117 bits (281), Expect = 2e-24
 Identities = 123/476 (25%), Positives = 204/476 (42%), Gaps = 52/476 (10%)

Query: 31   LNCRAGGSPSPAIRW-YKGGVLV-----VSDT-HRS----ILPAGGLFFLRATHGRVHSD 79
            ++C+A GSP P I W    G ++       D+ HR+    +   G L+F +       ++
Sbjct: 2058 VDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVGV----AE 2113

Query: 80   AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GDTVVLECLPPRGSP 136
             G Y C A N+ G    +   +H+ V+    R+   +K + +   GDT VL+C    G P
Sbjct: 2114 EGDYTCYAQNTLGKDEMK---VHLTVITAAPRIRQSNKTNKRIKAGDTAVLDC-EVTGDP 2169

Query: 137  EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
            +P ++W      ++     R      G+L I   +  D+G Y C+ARN +G  ++ +  L
Sbjct: 2170 KPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVKLLDSGEYVCVARNPSGD-DTKMYKL 2228

Query: 197  KIHIKPYLITG---PEDVVAQTG---SSVTFQCRVGGDPLPDVLWRRSAG-GGNMPL--G 247
             +  KP LI G      V+  T    S   F CR  G P P+V+W          P    
Sbjct: 2229 DVVSKPPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGS 2288

Query: 248  RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD----PPSINLSPNSVN 303
            R+ V  +G+L + NV L+D  ++ C A N  G       L V +    P   N     + 
Sbjct: 2289 RITVHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIV 2348

Query: 304  VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
             + G      C+  G P P + W +  N T    G     Y      +G  +  I+ T +
Sbjct: 2349 AQLGKSTALNCSVDGNPPPEIIW-ILPNGTRFSNG--PQSYQYLIASNGSFI--ISKTTR 2403

Query: 364  NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN-QTLPIKSMAVFPCTAI 422
             D+     C+A N  G  ++  KL +  +  + P I+T  P   + +  +S+++  C + 
Sbjct: 2404 EDA-GKYRCAARNKVG--YIE-KLVIL-EIGQKPVILTYAPGTVKGISGESLSLH-CVSD 2457

Query: 423  CTPEPIIAWYFEGEALIQNHRRN----VTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
              P+P I W      ++   + N    + ++GTLV+K+    D G Y C A +  G
Sbjct: 2458 GIPKPNIKWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVG 2513



 Score = 91.9 bits (218), Expect = 1e-16
 Identities = 70/273 (25%), Positives = 117/273 (42%), Gaps = 21/273 (7%)

Query: 31   LNCRAGGSPSPAIRWYKGGVLVVSD---THRSILPAGGLFFLRATHGRVHSDAGVYWCEA 87
            LNC   G+P P I W        S+   +++ ++ + G F +  T      DAG Y C A
Sbjct: 2357 LNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKT---TREDAGKYRCAA 2413

Query: 88   TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
             N  G    +   L +          P + +   G+++ L C+   G P+PN+ W     
Sbjct: 2414 RNKVGYIE-KLVILEIGQKPVILTYAPGTVKGISGESLSLHCVSD-GIPKPNIKWTMPSG 2471

Query: 148  TLL----FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY 203
             ++     +G   +H  D G LVI++A   D G Y C A+N+ G     +  + +   P 
Sbjct: 2472 YVVDRPQINGKYILH--DNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPR 2529

Query: 204  LIT-GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR------SAGGGNMPLGRVKVLDDGS 256
            +    P  +V +TG++    C   G P P++ W        S        G  ++   G+
Sbjct: 2530 ITNRPPRSIVTRTGAAFQLHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGT 2589

Query: 257  LRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
            L + N   +D G Y C A+N +G+  A+ Y+ V
Sbjct: 2590 LVIQNPQTSDSGIYKCTAKNPLGSDYAATYIQV 2622



 Score = 55.2 bits (127), Expect = 1e-05
 Identities = 50/167 (29%), Positives = 74/167 (44%), Gaps = 13/167 (7%)

Query: 122 GDTVVLECLPPRGSPEPNVYWK-KNGQTL---LFDGDSRMHLVDGGNLVIQDARQTDAGR 177
           G TV L C P +G P P+V W   +G  +       D R+ +   G L +Q A   D G 
Sbjct: 490 GGTVGLNC-PGQGDPTPHVDWLLADGSKVRAPYVSEDGRILIDKSGKLELQMADSFDTGV 548

Query: 178 YQCIARNAAGTRESAIATLKIHI-KPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDV 233
           Y CI+ N     ++ I T +I + +P +    E+ +  T   G ++   C   G P   +
Sbjct: 549 YHCISSNYD---DADILTYRITVVEPLVEAYQENGIHHTVFIGETLDLPCHSTGIPDASI 605

Query: 234 LWRRSAGGGNMPLGR-VKVLDDGSLRLDNVILADEGEYSCEAENSVG 279
            W            R  KVL++G+LR+  V   D+G Y C A N  G
Sbjct: 606 SWVIPGNNVLYQSSRDKKVLNNGTLRILQVTPKDQGYYRCVAANPSG 652



 Score = 53.6 bits (123), Expect = 3e-05
 Identities = 51/188 (27%), Positives = 77/188 (40%), Gaps = 15/188 (7%)

Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGG-NMPL----GRVKVLDDGSLRLDNVILADEGEY 270
           G +V   C   GDP P V W  + G     P     GR+ +   G L L      D G Y
Sbjct: 490 GGTVGLNCPGQGDPTPHVDWLLADGSKVRAPYVSEDGRILIDKSGKLELQMADSFDTGVY 549

Query: 271 SCEAENSVGAVSASGYLTVYDPPSINLSPNSVN--VESGNVARFTCTATGRPEPTMFWSV 328
            C + N   A   +  +TV +P       N ++  V  G      C +TG P+ ++ W +
Sbjct: 550 HCISSNYDDADILTYRITVVEPLVEAYQENGIHHTVFIGETLDLPCHSTGIPDASISWVI 609

Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT 388
            GN  +     SRDK     V +  T+  +  T K+  +    C A N +G  F+  +++
Sbjct: 610 PGNNVLY--QSSRDK----KVLNNGTLRILQVTPKD--QGYYRCVAANPSGVDFLIFQVS 661

Query: 389 VTSDDDRP 396
           V     RP
Sbjct: 662 VKMKGQRP 669



 Score = 50.8 bits (116), Expect = 2e-04
 Identities = 46/175 (26%), Positives = 71/175 (40%), Gaps = 11/175 (6%)

Query: 19  LDVTVARHQPATLNCRAGGSPSPAIRWY-----KGGVLVVSDTHRSILPAGGLFFLRATH 73
           L+ TV       LNC   G P+P + W      K     VS+  R ++   G   L+   
Sbjct: 483 LEHTVLVGGTVGLNCPGQGDPTPHVDWLLADGSKVRAPYVSEDGRILIDKSGKLELQMAD 542

Query: 74  GRVHSDAGVYWCEATNSYGTARSRNATLHVAV-LREEFRLEPESKQSAQGDTVVLECLPP 132
                D GVY C ++N Y  A      + V   L E ++          G+T+ L C   
Sbjct: 543 S---FDTGVYHCISSN-YDDADILTYRITVVEPLVEAYQENGIHHTVFIGETLDLPC-HS 597

Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
            G P+ ++ W   G  +L+       +++ G L I      D G Y+C+A N +G
Sbjct: 598 TGIPDASISWVIPGNNVLYQSSRDKKVLNNGTLRILQVTPKDQGYYRCVAANPSG 652



 Score = 49.6 bits (113), Expect = 5e-04
 Identities = 43/170 (25%), Positives = 68/170 (40%), Gaps = 9/170 (5%)

Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
           G      C   G P P + W +     +  P +S D      + D    L +   D  D+
Sbjct: 490 GGTVGLNCPGQGDPTPHVDWLLADGSKVRAPYVSED---GRILIDKSGKLELQMADSFDT 546

Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
                C + NY  +  +  ++TV   +        NG  + T+ I      PC +   P+
Sbjct: 547 -GVYHCISSNYDDADILTYRITVV--EPLVEAYQENG-IHHTVFIGETLDLPCHSTGIPD 602

Query: 427 PIIAWYFEGE-ALIQNHR-RNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
             I+W   G   L Q+ R + V N+GTL +  +   D G Y CVA++  G
Sbjct: 603 ASISWVIPGNNVLYQSSRDKKVLNNGTLRILQVTPKDQGYYRCVAANPSG 652


>UniRef50_Q49AK4 Cluster: DCC protein; n=9; Euteleostomi|Rep: DCC
           protein - Homo sapiens (Human)
          Length = 772

 Score =  155 bits (376), Expect = 7e-36
 Identities = 178/699 (25%), Positives = 278/699 (39%), Gaps = 78/699 (11%)

Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA-----RQTDAGRYQCIAR-NAAGTRES 191
           P + WKK+G  L    D R   +  G+L+IQ+       + D G YQC A    +G+  S
Sbjct: 4   PVIKWKKDGIHLALGMDERKQQLSNGSLLIQNILHSRHHKPDEGLYQCEASLGDSGSIIS 63

Query: 192 AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG--RV 249
             A + +      ++  E V A  G +V  +C V G+P+P + W+++        G  RV
Sbjct: 64  RTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRV 123

Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSAS-GYLTVYDPPSINLS------PNSV 302
            VL  G+L++  +   D G Y C A N   + + +   + +   P ++        P++V
Sbjct: 124 VVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEVRILSDPGLHRQLYFLQRPSNV 183

Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
               G  A      +G P P+  W + G   I    +   KY   ++  G  +L  N TD
Sbjct: 184 VAIEGKDAVLEGCVSGYPPPSFTW-LRGEEVI---QLRSKKY---SLLGGSNLLISNVTD 236

Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTA 421
            +    T V +  N   S+    +LTV       PP   N PSN     +SM + F CT 
Sbjct: 237 DDSGMYTCVVTYKNENISA--SAELTVLV-----PPWFLNHPSN-LYAYESMDIEFECTV 288

Query: 422 ICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
              P P + W   G+ +I +    +     L +  + KSD G Y CVA +  G    S  
Sbjct: 289 SGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQ 348

Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541
           L+V  P  P+         S LP  P   +   V+   V LSW    +    +I  + V 
Sbjct: 349 LIVPKPAIPS--------SSVLPSAPRDVVPVLVSSRFVRLSWRPPAE-AKGNIQTFTV- 398

Query: 542 VFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPV 601
            FSRE   G+N  R      +   +       V +L P   Y F V   N     GP   
Sbjct: 399 FFSRE---GDNRER-----ALNTTQPGSLQLTVGNLKPEAMYTFRVVAYNEW---GPGES 447

Query: 602 SDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYL 661
           S  + V         G                  VE ++A      +I + WE     Y 
Sbjct: 448 SQPIKVATQPELQVPGP-----------------VENLQAVSTSPTSILITWE--PPAYA 488

Query: 662 EGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNS 721
            G    +R         + + I    D   +++  L+K+T+Y    + + +   G  ++ 
Sbjct: 489 NGPVQGYRLFCTEVSTGKEQNI--EVDGLSYKLEGLKKFTEYSLRFLAYNRYGPGVSTDD 546

Query: 722 RVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKS 781
               TL DVP  PP N+ + ++N+ ++ + W PP    QNG ITGY +            
Sbjct: 547 ITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEME 606

Query: 782 MVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGP 820
            +  N   +     + T L  G  YS Q++A T+ G GP
Sbjct: 607 TLEPNNLWY-----LFTGLEKGSQYSFQVSAMTVNGTGP 640



 Score =  143 bits (346), Expect = 3e-32
 Identities = 123/390 (31%), Positives = 173/390 (44%), Gaps = 34/390 (8%)

Query: 41  PAIRWYKGGVLVV--SDTHRSILPAGGLFFLRATHGRVHS-DAGVYWCEAT-NSYGTARS 96
           P I+W K G+ +    D  +  L  G L      H R H  D G+Y CEA+    G+  S
Sbjct: 4   PVIKWKKDGIHLALGMDERKQQLSNGSLLIQNILHSRHHKPDEGLYQCEASLGDSGSIIS 63

Query: 97  RNATLHVA-VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL-FDGD 154
           R A + VA  LR  F  + ES  +  GDTV+L+C    G P P ++W+KN Q L    GD
Sbjct: 64  RTAKVAVAGPLR--FLSQTESVTAFMGDTVLLKC-EVIGEPMPTIHWQKNQQDLTPIPGD 120

Query: 155 SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI------HIKPYLITGP 208
           SR+ ++  G L I   +  D G Y+C ARN A +R    A ++I      H + Y +  P
Sbjct: 121 SRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEVRILSDPGLHRQLYFLQRP 180

Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268
            +VVA  G     +  V G P P   W R      +   +  +L   +L + NV   D G
Sbjct: 181 SNVVAIEGKDAVLEGCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSG 240

Query: 269 EYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328
            Y+C        +SAS  LTV  PP     P+++         F CT +G+P PT+ W  
Sbjct: 241 MYTCVVTYKNENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMK 300

Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT 388
            G+  ++ P    D +       G + L I    K+D      C A N AG++    +L 
Sbjct: 301 NGD--VVIPS---DYFQIV----GGSNLRILGVVKSD-EGFYQCVAENEAGNAQTSAQLI 350

Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
           V      P P I   PS+  LP     V P
Sbjct: 351 V------PKPAI---PSSSVLPSAPRDVVP 371



 Score =  118 bits (283), Expect = 1e-24
 Identities = 83/298 (27%), Positives = 134/298 (44%), Gaps = 20/298 (6%)

Query: 15  IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG---VLVVSDTHRSILPAGGLFFLRA 71
           + Q   VT        L C   G P P I W K       +  D+   +LP+G L   R 
Sbjct: 77  LSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRL 136

Query: 72  THGRVHSDAGVYWCEATNSYGTARSRNATLHV----AVLREEFRLE-PESKQSAQGDTVV 126
             G    D G+Y C A N   +     A + +     + R+ + L+ P +  + +G   V
Sbjct: 137 QPG----DIGIYRCSARNPASSRTGNEAEVRILSDPGLHRQLYFLQRPSNVVAIEGKDAV 192

Query: 127 LE-CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
           LE C+   G P P+  W + G+ ++     +  L+ G NL+I +    D+G Y C+    
Sbjct: 193 LEGCV--SGYPPPSFTWLR-GEEVIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVV-TY 248

Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
                SA A L + + P+ +  P ++ A     + F+C V G P+P V W ++ G   +P
Sbjct: 249 KNENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKN-GDVVIP 307

Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP--PSINLSPNS 301
               +++   +LR+  V+ +DEG Y C AEN  G    S  L V  P  PS ++ P++
Sbjct: 308 SDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSA 365



 Score = 69.7 bits (163), Expect = 4e-10
 Identities = 59/211 (27%), Positives = 87/211 (41%), Gaps = 14/211 (6%)

Query: 13  YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAGGLFFLRA 71
           Y +++P +V     + A L     G P P+  W +G  V+ +     S+L    L     
Sbjct: 175 YFLQRPSNVVAIEGKDAVLEGCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNV 234

Query: 72  THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
           T      D+G+Y C  T       S +A L V V    F   P +  + +   +  EC  
Sbjct: 235 T----DDDSGMYTCVVTYKNENI-SASAELTVLV-PPWFLNHPSNLYAYESMDIEFEC-T 287

Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
             G P P V W KNG  ++        +V G NL I    ++D G YQC+A N AG  ++
Sbjct: 288 VSGKPVPTVNWMKNGDVVI--PSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQT 345

Query: 192 AIATL----KIHIKPYLITGPEDVVAQTGSS 218
           +   +     I     L + P DVV    SS
Sbjct: 346 SAQLIVPKPAIPSSSVLPSAPRDVVPVLVSS 376



 Score = 46.0 bits (104), Expect = 0.006
 Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 4/85 (4%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P+ +  P ++           C   G P P + W K G +V+   +  I+    L  L  
Sbjct: 265 PWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRIL-- 322

Query: 72  THGRVHSDAGVYWCEATNSYGTARS 96
             G V SD G Y C A N  G A++
Sbjct: 323 --GVVKSDEGFYQCVAENEAGNAQT 345


>UniRef50_UPI0000E47894 Cluster: PREDICTED: similar to scavenger
            receptor cysteine-rich protein type 12 precursor; n=1;
            Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
            scavenger receptor cysteine-rich protein type 12
            precursor - Strongylocentrotus purpuratus
          Length = 2255

 Score =  155 bits (375), Expect = 9e-36
 Identities = 118/397 (29%), Positives = 177/397 (44%), Gaps = 33/397 (8%)

Query: 3    DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAI---RWYKGGVL-----VVS 54
            D  V S   P   E+P + T+     A   C+A G P+P +    W K G       + S
Sbjct: 1769 DCTVVSSYPPTFAEEPKNRTINAGSGALFRCKADGRPTPRVTVSSWLKDGQPLSQRDLSS 1828

Query: 55   DTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP 114
               R    +G L F+R        D+G Y C   N+ G   S +A L V          P
Sbjct: 1829 GRLRVYTSSGSLQFVRTR----REDSGNYTCVIRNTQGVNTS-SAFLVVKERPHIMSTHP 1883

Query: 115  ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTD 174
            +++    G+T  L C+   G PE  V W++NGQ L+  G+      + G L+I+D R  D
Sbjct: 1884 DTR--ILGETAELGCIVV-GLPESTVSWRRNGQPLM--GERFQSFGENGTLLIRDVRLED 1938

Query: 175  AGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL 234
             G Y+C+A N  G  + A   L ++  P  + GP+++  +TGS V+  C V G PLP++ 
Sbjct: 1939 NGMYECVAVNQLG-EDQASVKLTVYEVPTFLEGPQEMEVRTGSDVSIPCVVSGVPLPEIT 1997

Query: 235  WRRSAGGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
            W++   G  + L GRV +L+D +L +      D GEY+C A N V   +    L +  PP
Sbjct: 1998 WKKD--GQMISLNGRVTILEDNTLVIHKSQREDMGEYACIASNKVQTSARIAKLLIIGPP 2055

Query: 294  SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
             I  +P +    +G      CT  G   P + W   G   +       D+ H   V D  
Sbjct: 2056 HITEAPTNQTRVTGETVVLPCTVIGAYNPVVTWQHNGEDVV------NDERH-LMVDDS- 2107

Query: 354  TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT 390
              LT+ D D  D     VC+A N  G+      +++T
Sbjct: 2108 --LTVTDVDPADG-GLYVCTATNTEGAVSANAYVSIT 2141



 Score =  147 bits (355), Expect = 2e-33
 Identities = 114/391 (29%), Positives = 172/391 (43%), Gaps = 28/391 (7%)

Query: 110  FRLEPESKQSAQGDTVVLECLPPRGSPEPNVY---WKKNGQTL----LFDGDSRMHLVDG 162
            F  EP+++    G   +  C    G P P V    W K+GQ L    L  G  R++    
Sbjct: 1780 FAEEPKNRTINAGSGALFRCKAD-GRPTPRVTVSSWLKDGQPLSQRDLSSGRLRVY-TSS 1837

Query: 163  GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQ 222
            G+L     R+ D+G Y C+ RN  G   S+ A L +  +P++++   D     G +    
Sbjct: 1838 GSLQFVRTRREDSGNYTCVIRNTQGVNTSS-AFLVVKERPHIMSTHPDTRI-LGETAELG 1895

Query: 223  CRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVS 282
            C V G P   V WRR+ G   M        ++G+L + +V L D G Y C A N +G   
Sbjct: 1896 CIVVGLPESTVSWRRN-GQPLMGERFQSFGENGTLLIRDVRLEDNGMYECVAVNQLGEDQ 1954

Query: 283  ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRD 342
            AS  LTVY+ P+    P  + V +G+     C  +G P P + W  +G + I   G    
Sbjct: 1955 ASVKLTVYEVPTFLEGPQEMEVRTGSDVSIPCVVSGVPLPEITWKKDG-QMISLNG---- 2009

Query: 343  KYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN 402
                T + D    L I+ + + D      C A N   +S    KL +       PP IT 
Sbjct: 2010 --RVTILED--NTLVIHKSQRED-MGEYACIASNKVQTSARIAKLLIIG-----PPHITE 2059

Query: 403  GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDS 462
             P+NQT       V PCT I    P++ W   GE ++ N  R++  D +L + D+D +D 
Sbjct: 2060 APTNQTRVTGETVVLPCTVIGAYNPVVTWQHNGEDVV-NDERHLMVDDSLTVTDVDPADG 2118

Query: 463  GTYTCVASSRHGKYVWSGALLVDSPINPNIH 493
            G Y C A++  G    +  + +  P+    H
Sbjct: 2119 GLYVCTATNTEGAVSANAYVSITGPVRLGQH 2149



 Score = 60.1 bits (139), Expect = 4e-07
 Identities = 58/222 (26%), Positives = 93/222 (41%), Gaps = 18/222 (8%)

Query: 259  LDNVILADEGEYSCEA-ENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
            +D V ++D+     E  E  VG       ++ Y PP+    P +  + +G+ A F C A 
Sbjct: 1744 VDCVTVSDDQSVCLECPEGQVGNGIDCTVVSSY-PPTFAEEPKNRTINAGSGALFRCKAD 1802

Query: 318  GRPEPTM---FWSVEGNRTIIFPGMSRD-KYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
            GRP P +    W  +G      P   RD       V+     L    T + DS N   C 
Sbjct: 1803 GRPTPRVTVSSWLKDGQ-----PLSQRDLSSGRLRVYTSSGSLQFVRTRREDSGN-YTCV 1856

Query: 374  AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF 433
              N  G +     L V       P I++  P  + L     A   C  +  PE  ++W  
Sbjct: 1857 IRNTQGVNTSSAFLVV----KERPHIMSTHPDTRIL--GETAELGCIVVGLPESTVSWRR 1910

Query: 434  EGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
             G+ L+    ++   +GTL+++D+   D+G Y CVA ++ G+
Sbjct: 1911 NGQPLMGERFQSFGENGTLLIRDVRLEDNGMYECVAVNQLGE 1952


>UniRef50_UPI0000D8E943 Cluster: Down syndrome cell adhesion
            molecule-like protein 1 precursor (Down syndrome cell
            adhesion molecule 2).; n=1; Danio rerio|Rep: Down
            syndrome cell adhesion molecule-like protein 1 precursor
            (Down syndrome cell adhesion molecule 2). - Danio rerio
          Length = 1862

 Score =  155 bits (375), Expect = 9e-36
 Identities = 209/836 (25%), Positives = 341/836 (40%), Gaps = 79/836 (9%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P  I    ++T    +   +NCR  G P  +I+WYK G+L+  D HR ++   G   L+ 
Sbjct: 338  PPSIRAMRNITAVAGRNTFINCRVIGYPYYSIKWYKDGMLL-PDNHRQVVYENGT--LKL 394

Query: 72   THGRVHSDAGVYWCEATNSYGTARSRNA--TLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
            +  +   D G Y C        + S+    T+ V  L + F   P S     G  + + C
Sbjct: 395  SDVQKGMDEGAYLCSVLIQPQLSISQTVYVTVKVPPLIQPFDFPPTSI----GKLMYIAC 450

Query: 130  LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCIARNAA 186
            +   G     + W+K+GQ ++  G + + +       +L I        G Y CIA N A
Sbjct: 451  VVSSGDMPIRITWRKDGQEIV-SGTAGVTIETKEFMSSLQISKVSLKHNGNYTCIASNDA 509

Query: 187  GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN--- 243
             T  S    L + + P     P +     G S    C V G P P V+W+ + G GN   
Sbjct: 510  ATVSSE-RQLIVTVPPRFRVQPNNQDGIYGKSEVLNCSVEGYPPPKVVWKHAKGIGNPQQ 568

Query: 244  ---MPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLS 298
               +PL GR+++L +GSL + +V+  D G Y C+A N VG+ +S S  LTV  P  I   
Sbjct: 569  YHPVPLTGRIQILSNGSLLIRHVLEEDRGYYLCQASNGVGSDISKSMMLTVKIPAMITSH 628

Query: 299  PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV-----FDGV 353
            PN+     G      CTA G     + W  E   T+I P  +  +Y  T        + +
Sbjct: 629  PNTTMAIKGQNKELNCTARGEYPIIIRW--ERGDTVIDPDRN-PRYSITTSPNEKSDEVI 685

Query: 354  TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413
            + L +   ++ DS     C A+N  G      +LTV    D PP +      ++++ ++ 
Sbjct: 686  STLKLKPAERGDSV-FFSCHAINSYGEGRGLIQLTVQEPPD-PPELEVREVKDRSMNLRW 743

Query: 414  MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNV--TNDGTLVLKDLDKSDSGTYTCVASS 471
               F   +I T   I          +++  R +  TN+   ++ +L  +   +    + +
Sbjct: 744  TQRFDGNSIITSYDIEYKNKSDPWELKHATRKISPTNNQANIV-ELHPASVYSIRMYSYN 802

Query: 472  RHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK-I 530
            + G+   S  L + +   P              GPP + I   +T  S+ ++W    K +
Sbjct: 803  KIGRSQASKELTISTEEAPP------------DGPPMEVILQPMTSQSIRVTWKAPKKEL 850

Query: 531  GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590
             +  I GYQ+    RE   G+N        V +        Y + +L     Y  +V+  
Sbjct: 851  QNGVIRGYQIGY--RENGPGSN---GQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAF 905

Query: 591  NSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIK 650
            N  G +GPS    + T  +D         V +        +T   V   EA    S+  +
Sbjct: 906  NRAG-TGPSSSEINATTLED---------VPSQPPQNVRAIT---VTSDEAVITWSEPPR 952

Query: 651  LMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPF 710
            +    LN   L+G  + F  L       EM+ I  + +    E+  L K+T Y   ++ +
Sbjct: 953  MT---LNGV-LKGYRVVFWSLYPDGEWGEMQNITTTREQ--VELKGLEKFTNYSVQVLAY 1006

Query: 711  YKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVV 770
             +  +G  SN    QT +D P GPP  I+    + ++V + W PP     NGII  Y + 
Sbjct: 1007 TQAGDGVRSNVLYIQTREDHP-GPPAGIKAVPSSASSVVVSWLPP--VKPNGIIRKYTI- 1062

Query: 771  VNWLDVPANKSMVAINTTVHQATSLI-MTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
              +   P +          +    +  +T+LT G  Y +  AA T  G G  S+KV
Sbjct: 1063 --YCSSPGSGQPAPSEYEANPELLIYRITHLTRGQQYLIWAAAVTTAGRGNISEKV 1116



 Score =  117 bits (282), Expect = 2e-24
 Identities = 116/455 (25%), Positives = 184/455 (40%), Gaps = 39/455 (8%)

Query: 31  LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
           L C A G P+P IRW K G  + +D+  +    G    L  +  R+  D+G Y CE TNS
Sbjct: 78  LPCIASGYPNPTIRWLKDGRPLPADSRWTRRLTG----LTISDLRLE-DSGNYICEVTNS 132

Query: 91  YGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
           +G   S+  T H+ V+      L P++ ++    TV+L C   +GSP   V W +N + +
Sbjct: 133 FG---SKEVTGHLNVIEPLRVTLSPKNLKTGISSTVILSCAV-QGSPHFTVSWFRNTEPI 188

Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
           + D    +       L I  A++  +G YQC A     T +     L     P +++   
Sbjct: 189 VPDQHFSIQGAHNETLFITAAQKRHSGAYQCFATRKGQTAQDFSIILLEDGTPRIVSSFS 248

Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWR---RSAGGGNMPLGRVKVLDDGS----LRLDNV 262
           + V   G   +  C   G P P + W          +        L DGS    + + N 
Sbjct: 249 ERVVAPGEPFSLMCAAKGAPPPTITWTLDDEPVARDSAHRASQYTLSDGSTVSHVNVTNP 308

Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEP 322
            + D G Y C A NS G+      + V  PPSI    N +   +G      C   G P  
Sbjct: 309 QIRDGGVYRCAARNSAGSAEYQARINVRGPPSIRAMRN-ITAVAGRNTFINCRVIGYPYY 367

Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
           ++ W  +G   ++ P       H   V++  T L ++D  K       +CS +     S 
Sbjct: 368 SIKWYKDG---MLLP-----DNHRQVVYENGT-LKLSDVQKGMDEGAYLCSVLIQPQLS- 417

Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGEALIQN 441
           +   + VT    + PP+I       T  I  +    C       PI I W  +G+ ++  
Sbjct: 418 ISQTVYVTV---KVPPLIQPFDFPPT-SIGKLMYIACVVSSGDMPIRITWRKDGQEIVSG 473

Query: 442 HRRNVTND-----GTLVLKDLDKSDSGTYTCVASS 471
               VT +      +L +  +    +G YTC+AS+
Sbjct: 474 -TAGVTIETKEFMSSLQISKVSLKHNGNYTCIASN 507



 Score =  102 bits (244), Expect = 7e-20
 Identities = 138/561 (24%), Positives = 222/561 (39%), Gaps = 73/561 (13%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT-HRS----ILPAGGL 66
           P I+    +  VA  +P +L C A G+P P I W      V  D+ HR+    +     +
Sbjct: 241 PRIVSSFSERVVAPGEPFSLMCAAKGAPPPTITWTLDDEPVARDSAHRASQYTLSDGSTV 300

Query: 67  FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
             +  T+ ++  D GVY C A NS G+A  +     + V          +  +  G    
Sbjct: 301 SHVNVTNPQIR-DGGVYRCAARNSAGSAEYQ---ARINVRGPPSIRAMRNITAVAGRNTF 356

Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ-TDAGRYQC--IAR 183
           + C    G P  ++ W K+G  +L   + R  + + G L + D ++  D G Y C  + +
Sbjct: 357 INCRVI-GYPYYSIKWYKDG--MLLPDNHRQVVYENGTLKLSDVQKGMDEGAYLCSVLIQ 413

Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRRSAGGG 242
                 ++   T+K+   P LI   +      G  +   C V    +P  + WR+   G 
Sbjct: 414 PQLSISQTVYVTVKV---PPLIQPFDFPPTSIGKLMYIACVVSSGDMPIRITWRKD--GQ 468

Query: 243 NMPLGRVKVLDD-----GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
            +  G   V  +      SL++  V L   G Y+C A N    VS+   L V  PP   +
Sbjct: 469 EIVSGTAGVTIETKEFMSSLQISKVSLKHNGNYTCIASNDAATVSSERQLIVTVPPRFRV 528

Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
            PN+ +   G      C+  G P P + W  +  + I  P     +YH   +   + +L+
Sbjct: 529 QPNNQDGIYGKSEVLNCSVEGYPPPKVVW--KHAKGIGNP----QQYHPVPLTGRIQILS 582

Query: 358 INDT----DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413
                      + R   +C A N  GS   +  +       + P +IT+ P N T+ IK 
Sbjct: 583 NGSLLIRHVLEEDRGYYLCQASNGVGSDISKSMMLTV----KIPAMITSHP-NTTMAIKG 637

Query: 414 M-AVFPCTAICTPEPIIAWYFEGEALI---QNHRRNVTND---------GTLVLKDLDKS 460
                 CTA     PII  +  G+ +I   +N R ++T            TL LK  ++ 
Sbjct: 638 QNKELNCTA-RGEYPIIIRWERGDTVIDPDRNPRYSITTSPNEKSDEVISTLKLKPAERG 696

Query: 461 DSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSV 520
           DS  ++C A + +G+      L V  P                P PP   +   V D S+
Sbjct: 697 DSVFFSCHAINSYGEGRGLIQLTVQEP----------------PDPPELEV-REVKDRSM 739

Query: 521 TLSWSQNNKIGSSSILGYQVE 541
            L W+Q    G+S I  Y +E
Sbjct: 740 NLRWTQRFD-GNSIITSYDIE 759



 Score = 83.0 bits (196), Expect = 4e-14
 Identities = 87/357 (24%), Positives = 143/357 (40%), Gaps = 31/357 (8%)

Query: 155 SRMHLVDGGNLVIQDARQTDA-GRYQCIARN--AAGTRESAIATLKI----HIKPYLITG 207
           +R  L   G L I D ++ DA   Y+CI ++  +  TR+S  A L +       P ++  
Sbjct: 5   NRFFLTSYGALYISDVQKEDALSTYRCITKHKYSGETRQSNGARLSVLDPTESTPSVMDS 64

Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267
            +    Q G S+   C   G P P + W +   G  +P           L + ++ L D 
Sbjct: 65  FQSGEVQVGRSIELPCIASGYPNPTIRWLKD--GRPLPADSRWTRRLTGLTISDLRLEDS 122

Query: 268 GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327
           G Y CE  NS G+   +G+L V +P  + LSP ++     +    +C   G P  T+ W 
Sbjct: 123 GNYICEVTNSFGSKEVTGHLNVIEPLRVTLSPKNLKTGISSTVILSCAVQGSPHFTVSWF 182

Query: 328 VEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387
              N   I P    D++ +       T L I    K  S     C A     ++      
Sbjct: 183 --RNTEPIVP----DQHFSIQGAHNET-LFITAAQKRHS-GAYQCFATRKGQTA---QDF 231

Query: 388 TVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN--HRRN 445
           ++   +D  P I+++       P +  ++  C A   P P I W  + E + ++  HR +
Sbjct: 232 SIILLEDGTPRIVSSFSERVVAPGEPFSLM-CAAKGAPPPTITWTLDDEPVARDSAHRAS 290

Query: 446 --VTNDGTLV----LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFR 496
               +DG+ V    + +    D G Y C A +  G   +   + V  P  P+I   R
Sbjct: 291 QYTLSDGSTVSHVNVTNPQIRDGGVYRCAARNSAGSAEYQARINVRGP--PSIRAMR 345



 Score = 66.1 bits (154), Expect = 6e-09
 Identities = 71/267 (26%), Positives = 109/267 (40%), Gaps = 29/267 (10%)

Query: 269 EYSCEAENSVGAVSASGYLTVYDP----PSINLSPNSVNVESGNVARFTCTATGRPEPTM 324
           +YS E   S GA      L+V DP    PS+  S  S  V+ G      C A+G P PT+
Sbjct: 36  KYSGETRQSNGA-----RLSVLDPTESTPSVMDSFQSGEVQVGRSIELPCIASGYPNPTI 90

Query: 325 FWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR 384
            W  +G      P  SR     T        LTI+D    DS N  +C   N  GS  V 
Sbjct: 91  RWLKDGRP---LPADSRWTRRLTG-------LTISDLRLEDSGN-YICEVTNSFGSKEVT 139

Query: 385 GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR 444
           G L V       P  +T  P N    I S  +  C    +P   ++W+   E ++ +   
Sbjct: 140 GHLNVIE-----PLRVTLSPKNLKTGISSTVILSCAVQGSPHFTVSWFRNTEPIVPDQHF 194

Query: 445 NV--TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSS 502
           ++   ++ TL +    K  SG Y C A +R G+     ++++     P I    +  V +
Sbjct: 195 SIQGAHNETLFITAAQKRHSGAYQCFA-TRKGQTAQDFSIILLEDGTPRIVSSFSERVVA 253

Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNK 529
            PG P   +         T++W+ +++
Sbjct: 254 -PGEPFSLMCAAKGAPPPTITWTLDDE 279



 Score = 65.7 bits (153), Expect = 7e-09
 Identities = 52/191 (27%), Positives = 85/191 (44%), Gaps = 11/191 (5%)

Query: 643  PIDSKTIKLMWEI----LNFYYLEGLFIYFRPLD-NITIEYEMKTILHSNDVSGFEITSL 697
            P+ S++I++ W+     L    + G  I +R        +Y +  +  + D   + + +L
Sbjct: 833  PMTSQSIRVTWKAPKKELQNGVIRGYQIGYRENGPGSNGQYSIVEMKATGDSEVYTLDNL 892

Query: 698  RKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPEL 757
            +K+ +Y   +  F +   G  S+   A TL+DVP  PP N+    + +    + WS P  
Sbjct: 893  KKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPQNVRAITVTSDEAVITWSEPPR 952

Query: 758  QLQNGIITGYNVVVNWLDVPANK--SMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETI 815
               NG++ GY VV  W   P  +   M  I TT  Q     +  L    +YSVQ+ A T 
Sbjct: 953  MTLNGVLKGYRVVF-WSLYPDGEWGEMQNITTTREQVE---LKGLEKFTNYSVQVLAYTQ 1008

Query: 816  IGLGPFSQKVY 826
             G G  S  +Y
Sbjct: 1009 AGDGVRSNVLY 1019



 Score = 61.7 bits (143), Expect = 1e-07
 Identities = 52/176 (29%), Positives = 83/176 (47%), Gaps = 23/176 (13%)

Query: 370  IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
            I  +AV  AG   +  K+TV      P  I++ G +  T  +K + + PC+++  P P I
Sbjct: 1099 IWAAAVTTAGRGNISEKVTVEPAGKAPAKILSFGGTVTTPWMKEVRL-PCSSVGEPTPTI 1157

Query: 430  AWYFEGE----ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485
             W  + E     + Q+  RN+ ++GTLVL+ +   DSG YTC A++  G       LLV 
Sbjct: 1158 KWTKDSEDTAIPVTQDGHRNILSNGTLVLRSVKAEDSGYYTCTATNTLGFDTIIVNLLVQ 1217

Query: 486  SPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541
             P                P  P   ++   T +S+TL+W   +  G SSI G+ ++
Sbjct: 1218 VP----------------PDQPRLTVSTTST-SSITLAWIPGDN-GGSSIRGFVLQ 1255



 Score = 56.0 bits (129), Expect = 6e-06
 Identities = 41/169 (24%), Positives = 70/169 (41%), Gaps = 8/169 (4%)

Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
           I  L   + Y   +  + K    + S      T +  PDGPP+ + +  + + ++ + W 
Sbjct: 785 IVELHPASVYSIRMYSYNKIGRSQASKELTISTEEAPPDGPPMEVILQPMTSQSIRVTWK 844

Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMT--NLTSGVSYSVQIA 811
            P+ +LQNG+I GY +     + P +    +I        S + T  NL     Y V + 
Sbjct: 845 APKKELQNGVIRGYQIGYR-ENGPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQ 903

Query: 812 AETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETW 860
           A    G GP S ++     + +   D+ S+ P N     V  D  + TW
Sbjct: 904 AFNRAGTGPSSSEI-----NATTLEDVPSQPPQNVRAITVTSDEAVITW 947



 Score = 45.2 bits (102), Expect = 0.011
 Identities = 45/166 (27%), Positives = 68/166 (40%), Gaps = 15/166 (9%)

Query: 131  PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
            P  G P P+ Y + N + L++      HL  G   +I  A  T AGR     +       
Sbjct: 1067 PGSGQPAPSEY-EANPELLIY---RITHLTRGQQYLIWAAAVTTAGRGNISEK--VTVEP 1120

Query: 191  SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL---G 247
            +  A  KI      +T P          V   C   G+P P + W + +    +P+   G
Sbjct: 1121 AGKAPAKILSFGGTVTTP------WMKEVRLPCSSVGEPTPTIKWTKDSEDTAIPVTQDG 1174

Query: 248  RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
               +L +G+L L +V   D G Y+C A N++G  +    L V  PP
Sbjct: 1175 HRNILSNGTLVLRSVKAEDSGYYTCTATNTLGFDTIIVNLLVQVPP 1220



 Score = 44.0 bits (99), Expect = 0.025
 Identities = 31/90 (34%), Positives = 44/90 (48%), Gaps = 9/90 (10%)

Query: 8    SGEAPY-IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG----GVLVVSDTHRSILP 62
            +G+AP  I+     VT    +   L C + G P+P I+W K      + V  D HR+IL 
Sbjct: 1121 AGKAPAKILSFGGTVTTPWMKEVRLPCSSVGEPTPTIKWTKDSEDTAIPVTQDGHRNIL- 1179

Query: 63   AGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
            + G   LR+       D+G Y C ATN+ G
Sbjct: 1180 SNGTLVLRSVKA---EDSGYYTCTATNTLG 1206



 Score = 42.3 bits (95), Expect = 0.078
 Identities = 38/153 (24%), Positives = 63/153 (41%), Gaps = 10/153 (6%)

Query: 134  GSPEPNVYWKKNGQ--TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
            G P P + W K+ +   +    D   +++  G LV++  +  D+G Y C A N  G  ++
Sbjct: 1151 GEPTPTIKWTKDSEDTAIPVTQDGHRNILSNGTLVLRSVKAEDSGYYTCTATNTLGF-DT 1209

Query: 192  AIATLKIHIKPYLITGPEDVVAQTG-SSVTFQC---RVGGDPLPDVLWRRSAGGGNMPLG 247
             I  L + + P     P   V+ T  SS+T        GG  +   + + S         
Sbjct: 1210 IIVNLLVQVPP---DQPRLTVSTTSTSSITLAWIPGDNGGSSIRGFVLQYSVDNTEEWKD 1266

Query: 248  RVKVLDDGSLRLDNVILADEGEYSCEAENSVGA 280
                  + S +LDN+      +    A+NSVGA
Sbjct: 1267 VFISSSERSFKLDNLRCGTWYKVKLAAKNSVGA 1299


>UniRef50_A6BM71 Cluster: Connectin; n=8; Gallus gallus|Rep: Connectin
            - Gallus gallus (Chicken)
          Length = 8074

 Score =  155 bits (375), Expect = 9e-36
 Identities = 137/498 (27%), Positives = 208/498 (41%), Gaps = 30/498 (6%)

Query: 2    SDDYVTSGEAPYIIEQPLDVT--VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRS 59
            S  ++T  E P  I++ LD +  V +H      C+ GGSP   + WYKG   +      S
Sbjct: 3266 STAFLTVTEPPRFIKK-LDSSRLVKQHDSTRYECKVGGSPEIKVTWYKGETEIHPSEKYS 3324

Query: 60   ILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS 119
            +     +  L   H     D+G Y CEA N  G+A S + +L V      F  +P   Q+
Sbjct: 3325 MSFVDSVAVLEM-HNLSVEDSGDYSCEAQNPAGSA-STSTSLKVKA-PPAFTKKPHPVQT 3381

Query: 120  AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV----IQDARQTDA 175
             +G  V LEC   +G+P   + W K+ + +     S+ + V   N +    I +    D 
Sbjct: 3382 LKGSDVHLEC-ELQGTPPFQISWYKDKREIR---SSKKYKVMSENYLASIHILNVDTADV 3437

Query: 176  GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
            G Y C A N  G+ +S I ++ +   P  +    DV    G ++  Q  V G     VLW
Sbjct: 3438 GEYHCKAVNDVGS-DSCIGSVTLRAPPTFVKKLSDVTVVVGETIELQAAVEGAQPISVLW 3496

Query: 236  RRSAGGGNMPLGRVKVL---DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
             +  G        + +    +  SL++ N    + G+Y C+ +N  G       LTV +P
Sbjct: 3497 LKDKGEIIRESENLWISYSENVASLKIGNAEPTNAGKYICQIKNDAGFQECFAKLTVLEP 3556

Query: 293  PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
              I   P  V V +G+     CT  G PE T  W  +GN       +S D  +  + F+ 
Sbjct: 3557 AVIVEKPGPVKVTAGDSCTLECTVDGTPELTARWFKDGNE------LSTDHKYKISFFNK 3610

Query: 353  VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
            V+ L I +    DS         N  G S     L V+  D   PP  T         + 
Sbjct: 3611 VSGLKILNAGLEDS-GEYTFEVKNSVGKSSCTASLQVS--DRIMPPSFTRKLKETYGQLG 3667

Query: 413  SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT-NDGTLVLK--DLDKSDSGTYTCVA 469
            S AV  C    +P  +++W+ +G+ +    +   T  D T  LK   L +SD GTY+C A
Sbjct: 3668 SSAVLECKVYGSPPILVSWFHDGQEITSGDKYQATLTDNTCSLKVNGLQESDMGTYSCTA 3727

Query: 470  SSRHGKYVWSGALLVDSP 487
            ++  G    S  L V  P
Sbjct: 3728 TNVAGSDECSAFLSVREP 3745



 Score =  139 bits (337), Expect = 4e-31
 Identities = 136/541 (25%), Positives = 221/541 (40%), Gaps = 26/541 (4%)

Query: 5    YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
            +++  E P  +++P    V   +  T      GSP   ++W++G + +      +I    
Sbjct: 3739 FLSVREPPSFVKKPEPFNVLSGENITFTSIVKGSPPLEVKWFRGSIELAPGHKCNITLQD 3798

Query: 65   GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR-EEFRLEPESKQSAQGD 123
             +  L     +    +G Y C+ +N  G     + T H+ V    +F ++       +G 
Sbjct: 3799 SVAELELFDVQ-PLQSGDYTCQVSNEAGKI---SCTTHLFVKEPAKFVMKVNDLSVEKGK 3854

Query: 124  TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIA 182
             ++LEC    G+P  +V WKKNG  L       +   +    L I +++  D G+Y C  
Sbjct: 3855 NLILEC-TYTGTPPISVTWKKNGVILKHSEKCSITTTETSAILEIPNSKLEDQGQYSCHI 3913

Query: 183  RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR--SAG 240
             N +G +++    + I   PY +T  E V    G S + QC+V G P   V W +  +  
Sbjct: 3914 ENDSG-QDNCHGAITILEPPYFVTPLEPVQVTVGDSASLQCQVAGTPEMIVSWYKGDTKL 3972

Query: 241  GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINL 297
             G   +         +L    V   D GEY C+ EN+VG  ++S  LTV +   PPS   
Sbjct: 3973 RGTATVKMHFKNQVATLVFSQVDSDDSGEYICKVENTVGEATSSSLLTVQERKLPPSFTR 4032

Query: 298  SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
                V+   G    F C   G     + W  +  R      +  D    T+  D V +L 
Sbjct: 4033 KLRDVHETVGLPVTFDCGIAGSEPIEVSWFKDNVR------VKEDYNVHTSFIDNVAILQ 4086

Query: 358  INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
            I  TDK+       C+A N  G++   GKL +T  + + PP      +     I   A F
Sbjct: 4087 ILKTDKS-LMGQYTCTASNAIGTASSSGKLVLT--EGKTPPFFDTPITPVDGIIGESADF 4143

Query: 418  PCTAICTPEPIIAWYFEGEALIQ--NHRRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
             C    T    + W  + + +    N++ + V N   L +  +D+ DSG YTC AS+  G
Sbjct: 4144 ECHISGTQPIRVTWAKDNQEIRTGGNYQISYVENTAHLTILRVDRGDSGKYTCYASNEVG 4203

Query: 475  KYVWSGALLVDSPINPNIHFFRAAD-VSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSS 533
            K   +  L V     P     + ++ V    G   K          +T+SW +NN+   S
Sbjct: 4204 KDSCTAQLNVKERKTPPTFTRKLSEAVEETEGNELKLEGRVAGSQPLTVSWYKNNQEVHS 4263

Query: 534  S 534
            S
Sbjct: 4264 S 4264



 Score =  133 bits (321), Expect = 3e-29
 Identities = 128/483 (26%), Positives = 194/483 (40%), Gaps = 29/483 (6%)

Query: 17   QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV 76
            +PL+V V  +  A   C    +P+   +WYK G  +      SI  +  L  L     +V
Sbjct: 3190 EPLEVAV--NHVAKFTCEVETTPNVKFQWYKAGREIYDGDKYSIRSSNYLSTLEIPRPQV 3247

Query: 77   HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
              D G Y C+A+N +G+  S  A L V       +    S+   Q D+   EC    GSP
Sbjct: 3248 -VDCGEYSCKASNQHGSV-SSTAFLTVTEPPRFIKKLDSSRLVKQHDSTRYEC-KVGGSP 3304

Query: 137  EPNVYWKKNGQTLLFDGDS-RMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194
            E  V W K G+T +   +   M  VD    L + +    D+G Y C A+N AG+  S   
Sbjct: 3305 EIKVTWYK-GETEIHPSEKYSMSFVDSVAVLEMHNLSVEDSGDYSCEAQNPAGS-ASTST 3362

Query: 195  TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254
            +LK+   P     P  V    GS V  +C + G P   + W +          + KV+ +
Sbjct: 3363 SLKVKAPPAFTKKPHPVQTLKGSDVHLECELQGTPPFQISWYKDKREIRSS-KKYKVMSE 3421

Query: 255  ---GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVAR 311
                S+ + NV  AD GEY C+A N VG+ S  G +T+  PP+     + V V  G    
Sbjct: 3422 NYLASIHILNVDTADVGEYHCKAVNDVGSDSCIGSVTLRAPPTFVKKLSDVTVVVGETIE 3481

Query: 312  FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF-DGVTVLTINDTDKNDSRNTI 370
                  G    ++ W  +    I      R+  +    + + V  L I + +  ++    
Sbjct: 3482 LQAAVEGAQPISVLWLKDKGEII------RESENLWISYSENVASLKIGNAEPTNA-GKY 3534

Query: 371  VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA 430
            +C   N AG      KLTV       P +I   P    +         CT   TPE    
Sbjct: 3535 ICQIKNDAGFQECFAKLTVLE-----PAVIVEKPGPVKVTAGDSCTLECTVDGTPELTAR 3589

Query: 431  WYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
            W+ +G  L  +H+  ++       L + +    DSG YT    +  GK   + +L V   
Sbjct: 3590 WFKDGNELSTDHKYKISFFNKVSGLKILNAGLEDSGEYTFEVKNSVGKSSCTASLQVSDR 3649

Query: 488  INP 490
            I P
Sbjct: 3650 IMP 3652



 Score =  127 bits (306), Expect = 2e-27
 Identities = 123/508 (24%), Positives = 195/508 (38%), Gaps = 22/508 (4%)

Query: 29   ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
            A L C+  GSP   + W+  G  + S              L+  +G   SD G Y C AT
Sbjct: 3670 AVLECKVYGSPPILVSWFHDGQEITSGDKYQATLTDNTCSLKV-NGLQESDMGTYSCTAT 3728

Query: 89   NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
            N  G+    +A L V      F  +PE      G+ +    +  +GSP   V W +    
Sbjct: 3729 NVAGSDEC-SAFLSVRE-PPSFVKKPEPFNVLSGENITFTSIV-KGSPPLEVKWFRGSIE 3785

Query: 149  LLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG 207
            L       + L D    L + D +   +G Y C   N AG + S    L +      +  
Sbjct: 3786 LAPGHKCNITLQDSVAELELFDVQPLQSGDYTCQVSNEAG-KISCTTHLFVKEPAKFVMK 3844

Query: 208  PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG--GGNMPLGRVKVLDDGSLRLDNVILA 265
              D+  + G ++  +C   G P   V W+++      +             L + N  L 
Sbjct: 3845 VNDLSVEKGKNLILECTYTGTPPISVTWKKNGVILKHSEKCSITTTETSAILEIPNSKLE 3904

Query: 266  DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325
            D+G+YSC  EN  G  +  G +T+ +PP        V V  G+ A   C   G PE  + 
Sbjct: 3905 DQGQYSCHIENDSGQDNCHGAITILEPPYFVTPLEPVQVTVGDSASLQCQVAGTPEMIVS 3964

Query: 326  WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385
            W  +G+  +   G +  K H     + V  L  +  D +DS    +C   N  G +    
Sbjct: 3965 W-YKGDTKL--RGTATVKMHFK---NQVATLVFSQVDSDDS-GEYICKVENTVGEATSSS 4017

Query: 386  KLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGEALIQN--- 441
             LTV   + + PP  T    +    +     F C  I   EPI ++W+ +   + ++   
Sbjct: 4018 LLTV--QERKLPPSFTRKLRDVHETVGLPVTFDC-GIAGSEPIEVSWFKDNVRVKEDYNV 4074

Query: 442  HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVS 501
            H   + N   L +   DKS  G YTC AS+  G    SG L++     P         V 
Sbjct: 4075 HTSFIDNVAILQILKTDKSLMGQYTCTASNAIGTASSSGKLVLTEGKTPPFFDTPITPVD 4134

Query: 502  SLPGPPTKPITHNVTDTSVTLSWSQNNK 529
             + G       H      + ++W+++N+
Sbjct: 4135 GIIGESADFECHISGTQPIRVTWAKDNQ 4162



 Score =  120 bits (290), Expect = 2e-25
 Identities = 121/495 (24%), Positives = 201/495 (40%), Gaps = 45/495 (9%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
            D++V + +   L C   G+P  ++ W K GV++      SI        L   + ++  D
Sbjct: 3847 DLSVEKGKNLILECTYTGTPPISVTWKKNGVILKHSEKCSITTTETSAILEIPNSKLE-D 3905

Query: 80   AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVLECLPPRGSPEP 138
             G Y C   N  G      A   + +L   + + P E  Q   GD+  L+C    G+PE 
Sbjct: 3906 QGQYSCHIENDSGQDNCHGA---ITILEPPYFVTPLEPVQVTVGDSASLQC-QVAGTPEM 3961

Query: 139  NVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAG--TRESAIAT 195
             V W K    L      +MH  +    LV       D+G Y C   N  G  T  S +  
Sbjct: 3962 IVSWYKGDTKLRGTATVKMHFKNQVATLVFSQVDSDDSGEYICKVENTVGEATSSSLLTV 4021

Query: 196  LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
             +  + P       DV    G  VTF C + G    +V W +           V+V +D 
Sbjct: 4022 QERKLPPSFTRKLRDVHETVGLPVTFDCGIAGSEPIEVSWFKD---------NVRVKEDY 4072

Query: 256  SLR---LDNVIL-----ADE---GEYSCEAENSVGAVSASGYLTVYD---PPSINLSPNS 301
            ++    +DNV +      D+   G+Y+C A N++G  S+SG L + +   PP  +     
Sbjct: 4073 NVHTSFIDNVAILQILKTDKSLMGQYTCTASNAIGTASSSGKLVLTEGKTPPFFDTPITP 4132

Query: 302  VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
            V+   G  A F C  +G     + W+ + N+ I   G  +  Y      +    LTI   
Sbjct: 4133 VDGIIGESADFECHISGTQPIRVTWAKD-NQEIRTGGNYQISY-----VENTAHLTILRV 4186

Query: 362  DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
            D+ DS     C A N  G      +L V   + + PP  T   S      +   +     
Sbjct: 4187 DRGDS-GKYTCYASNEVGKDSCTAQLNVK--ERKTPPTFTRKLSEAVEETEGNELKLEGR 4243

Query: 422  ICTPEPI-IAWYFEGEALIQNHRRNVT-NDGTLVL--KDLDKSDSGTYTCVASSRHGKYV 477
            +   +P+ ++WY   + +  +    ++  + TL+L  K + +SD+G YTC  S+  G  +
Sbjct: 4244 VAGSQPLTVSWYKNNQEVHSSPHCEISFKNNTLLLHIKSVGQSDAGLYTCKVSNEAGSVL 4303

Query: 478  WSGALLVDSPINPNI 492
             + ++++  P  P +
Sbjct: 4304 CTSSVVIREPKKPPV 4318



 Score =  109 bits (263), Expect = 3e-22
 Identities = 125/494 (25%), Positives = 199/494 (40%), Gaps = 31/494 (6%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAG 64
            VT    P  +++  DVTV   +   L     G+   ++ W K  G ++    +  I  + 
Sbjct: 3457 VTLRAPPTFVKKLSDVTVVVGETIELQAAVEGAQPISVLWLKDKGEIIRESENLWISYSE 3516

Query: 65   GLFFLRATHGRVHSDAGVYWCEATNSYGTAR--SRNATLHVAVLREEFRLEPESKQSAQG 122
             +  L+  +    ++AG Y C+  N  G     ++   L  AV+ E+    P   +   G
Sbjct: 3517 NVASLKIGNAEP-TNAGKYICQIKNDAGFQECFAKLTVLEPAVIVEK----PGPVKVTAG 3571

Query: 123  DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCI 181
            D+  LEC    G+PE    W K+G  L  D   ++   +    L I +A   D+G Y   
Sbjct: 3572 DSCTLECTVD-GTPELTARWFKDGNELSTDHKYKISFFNKVSGLKILNAGLEDSGEYTFE 3630

Query: 182  ARNAAGTRESAIATLKI--HIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238
             +N+ G + S  A+L++   I P   T   ++   Q GSS   +C+V G P   V W   
Sbjct: 3631 VKNSVG-KSSCTASLQVSDRIMPPSFTRKLKETYGQLGSSAVLECKVYGSPPILVSWFHD 3689

Query: 239  AGGGNMPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
                         L D   SL+++ +  +D G YSC A N  G+   S +L+V +PPS  
Sbjct: 3690 GQEITSGDKYQATLTDNTCSLKVNGLQESDMGTYSCTATNVAGSDECSAFLSVREPPSFV 3749

Query: 297  LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
              P   NV SG    FT    G P   + W   G+  +  PG    K + T + D V  L
Sbjct: 3750 KKPEPFNVLSGENITFTSIVKGSPPLEVKW-FRGSIELA-PG---HKCNIT-LQDSVAEL 3803

Query: 357  TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416
             + D     S     C   N AG       L V     + P       ++ ++      +
Sbjct: 3804 ELFDVQPLQS-GDYTCQVSNEAGKISCTTHLFV-----KEPAKFVMKVNDLSVEKGKNLI 3857

Query: 417  FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS---DSGTYTCVASSRH 473
              CT   TP   + W   G  L  + + ++T   T  + ++  S   D G Y+C   +  
Sbjct: 3858 LECTYTGTPPISVTWKKNGVILKHSEKCSITTTETSAILEIPNSKLEDQGQYSCHIENDS 3917

Query: 474  GKYVWSGALLVDSP 487
            G+    GA+ +  P
Sbjct: 3918 GQDNCHGAITILEP 3931



 Score =  103 bits (246), Expect = 4e-20
 Identities = 122/486 (25%), Positives = 197/486 (40%), Gaps = 41/486 (8%)

Query: 28   PATLNCRAGGSPSPAIRWYKGGVLVVSD--THRSILPAGGLFFLRATHGRVHSDAGVYWC 85
            P T +C   GS    + W+K  V V  D   H S +    +  +  T     S  G Y C
Sbjct: 4044 PVTFDCGIAGSEPIEVSWFKDNVRVKEDYNVHTSFIDNVAILQILKTD---KSLMGQYTC 4100

Query: 86   EATNSYGTARSRNATLHVAVLREEFRLEPESK-QSAQGDTVVLECLPPRGSPEPNVYWKK 144
             A+N+ GTA S    +        F   P +      G++   EC    G+    V W K
Sbjct: 4101 TASNAIGTASSSGKLVLTEGKTPPFFDTPITPVDGIIGESADFEC-HISGTQPIRVTWAK 4159

Query: 145  NGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK-- 201
            + Q +   G+ ++  V+   +L I    + D+G+Y C A N  G ++S  A L +  +  
Sbjct: 4160 DNQEIRTGGNYQISYVENTAHLTILRVDRGDSGKYTCYASNEVG-KDSCTAQLNVKERKT 4218

Query: 202  -PYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLW-RRSAGGGNMPLGRVKVLDDGSL- 257
             P       + V +T G+ +  + RV G     V W + +    + P   +   ++  L 
Sbjct: 4219 PPTFTRKLSEAVEETEGNELKLEGRVAGSQPLTVSWYKNNQEVHSSPHCEISFKNNTLLL 4278

Query: 258  RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP---PSINLSPNSVNVESGNVARFTC 314
             + +V  +D G Y+C+  N  G+V  +  + + +P   P  +        E G+  + +C
Sbjct: 4279 HIKSVGQSDAGLYTCKVSNEAGSVLCTSSVVIREPKKPPVFDQPLQPAATEEGDTLQLSC 4338

Query: 315  TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF-DGVTVLTINDTDKNDSRNTIVCS 373
               G  EP     ++  R I      R     +  F +GV +L +    K+DS    VC 
Sbjct: 4339 HVRGS-EPIRIQWLKAGREI------RASERCSFSFANGVALLELAAVTKSDS-GEYVCK 4390

Query: 374  AVNYAGSSFVRGKLTVTSD----------DDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
            A N AG+   R K+TV             D        + P +  +  K++A F      
Sbjct: 4391 ASNVAGTDTCRSKVTVKEKAALVSAAKKADIEGKLYFVSEPQSIKVMEKTVATFIAKVGG 4450

Query: 424  TPEPIIAWYF-EGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWS 479
             P P + W   +   L Q  R  +   G    L +KD  K+DSG Y CVA ++HG+   S
Sbjct: 4451 DPIPNVKWMKGKWRQLNQGGRIIIQQRGDEAKLEIKDTTKTDSGLYKCVAFNQHGEIERS 4510

Query: 480  GALLVD 485
              L V+
Sbjct: 4511 VNLQVE 4516



 Score =  101 bits (241), Expect = 2e-19
 Identities = 138/521 (26%), Positives = 202/521 (38%), Gaps = 55/521 (10%)

Query: 5    YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
            YV + E P II++    TV   +PA       G P P + WYK    +        L   
Sbjct: 2959 YVNAPEPPQIIQELQPTTVESGKPARFCAIISGKPQPKVSWYKDDQQLSPGFKCKFLHDA 3018

Query: 65   GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-----EFRLEPESKQS 119
              + L         D+ VY CEA N YG A + +A+L V +        E  + P +   
Sbjct: 3019 QEYTLLLIE-TFPEDSAVYTCEAKNDYGVA-TTSASLSVEIPEVVSPELEVPVYPPAVIV 3076

Query: 120  AQGDTVVLECLPPR-----GSPEPNVYWKKNGQTLLFDGDSRM-HLVDGGNLVIQDARQT 173
               D V  E    R        +  V W    + +      RM    D   L I +A   
Sbjct: 3077 PLRDAVTSEGQSARFQCRVTGTDLKVSWYSKDREIKPSRFFRMTQFEDTYQLEIAEAYPE 3136

Query: 174  DAGRYQCIARNAAG-TRESAIATL-----------------KIHIKPYLITGPEDVVAQT 215
            D G Y  +A N+ G    +AI  L                 ++ + P L    E +    
Sbjct: 3137 DEGTYTFVASNSVGQVTSTAILKLEAPEKIMYEKLEEEIEMEVKVAPILRRRLEPLEVAV 3196

Query: 216  GSSVTFQCRVGGDPLPDVLW----RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYS 271
                 F C V   P     W    R    G    +     L   +L +    + D GEYS
Sbjct: 3197 NHVAKFTCEVETTPNVKFQWYKAGREIYDGDKYSIRSSNYL--STLEIPRPQVVDCGEYS 3254

Query: 272  CEAENSVGAVSASGYLTVYDPPS-INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
            C+A N  G+VS++ +LTV +PP  I    +S  V+  +  R+ C   G PE  + W  +G
Sbjct: 3255 CKASNQHGSVSSTAFLTVTEPPRFIKKLDSSRLVKQHDSTRYECKVGGSPEIKVTW-YKG 3313

Query: 331  NRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT 390
              T I P    +KY  + V D V VL +++    DS     C A N AGS+      T T
Sbjct: 3314 -ETEIHPS---EKYSMSFV-DSVAVLEMHNLSVEDS-GDYSCEAQNPAGSA-----STST 3362

Query: 391  SDDDRPPPIITNGPSN-QTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND 449
            S   + PP  T  P   QTL   S     C    TP   I+WY +   +  + +  V ++
Sbjct: 3363 SLKVKAPPAFTKKPHPVQTLK-GSDVHLECELQGTPPFQISWYKDKREIRSSKKYKVMSE 3421

Query: 450  GTLV---LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
              L    + ++D +D G Y C A +  G     G++ + +P
Sbjct: 3422 NYLASIHILNVDTADVGEYHCKAVNDVGSDSCIGSVTLRAP 3462



 Score =  101 bits (241), Expect = 2e-19
 Identities = 123/491 (25%), Positives = 191/491 (38%), Gaps = 42/491 (8%)

Query: 6    VTSGEAPYIIE--QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
            +T  E PY +   +P+ VTV     A+L C+  G+P   + WYKG   +       +   
Sbjct: 3926 ITILEPPYFVTPLEPVQVTVG--DSASLQCQVAGTPEMIVSWYKGDTKLRGTATVKMHFK 3983

Query: 64   GGLFFLRATHGRVHS-DAGVYWCEATNSYGTARSRN-ATLHVAVLREEFRLEPESKQSAQ 121
              +  L     +V S D+G Y C+  N+ G A S +  T+    L   F  +        
Sbjct: 3984 NQVATL--VFSQVDSDDSGEYICKVENTVGEATSSSLLTVQERKLPPSFTRKLRDVHETV 4041

Query: 122  GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTD---AGRY 178
            G  V  +C    GS    V W K+   +  D +     +D  N+ I    +TD    G+Y
Sbjct: 4042 GLPVTFDC-GIAGSEPIEVSWFKDNVRVKEDYNVHTSFID--NVAILQILKTDKSLMGQY 4098

Query: 179  QCIARNAAGTRESA--IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
             C A NA GT  S+  +   +    P+  T    V    G S  F+C + G     V W 
Sbjct: 4099 TCTASNAIGTASSSGKLVLTEGKTPPFFDTPITPVDGIIGESADFECHISGTQPIRVTWA 4158

Query: 237  RS----AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD- 291
            +       GGN  +  V+  +   L +  V   D G+Y+C A N VG  S +  L V + 
Sbjct: 4159 KDNQEIRTGGNYQISYVE--NTAHLTILRVDRGDSGKYTCYASNEVGKDSCTAQLNVKER 4216

Query: 292  --PPSINLS-PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
              PP+       +V    GN  +      G    T+ W  + N+ +          H   
Sbjct: 4217 KTPPTFTRKLSEAVEETEGNELKLEGRVAGSQPLTVSW-YKNNQEV------HSSPHCEI 4269

Query: 349  VFDGVTVLT-INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407
             F   T+L  I    ++D+     C   N AGS      + +   + + PP+  + P   
Sbjct: 4270 SFKNNTLLLHIKSVGQSDA-GLYTCKVSNEAGSVLCTSSVVIR--EPKKPPVF-DQPLQP 4325

Query: 408  TLPIKSMAVFPCTAICTPEPI-IAWYFEGEALIQNHRRNVTNDGTLVLKDL---DKSDSG 463
                +   +     +   EPI I W   G  +  + R + +    + L +L    KSDSG
Sbjct: 4326 AATEEGDTLQLSCHVRGSEPIRIQWLKAGREIRASERCSFSFANGVALLELAAVTKSDSG 4385

Query: 464  TYTCVASSRHG 474
             Y C AS+  G
Sbjct: 4386 EYVCKASNVAG 4396



 Score = 78.6 bits (185), Expect = 1e-12
 Identities = 178/812 (21%), Positives = 299/812 (36%), Gaps = 98/812 (12%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
            D  V   Q    NC      +   +WYK G  +       I+    ++ LR    ++  D
Sbjct: 6885 DQEVNEGQEIIFNCEVNKEGAKE-KWYKNGEAIFDSAKYIIVQKDLVYTLRIRDTQL-KD 6942

Query: 80   AGVYWCEATNSYGTARSRNATLHVAVLREEFRL-EP-ESKQSAQGDTVVLECLPPRGSPE 137
               Y    +N  G     +A L   VL E  R+ EP E  ++ +  TV   C   R +  
Sbjct: 6943 QATYSISLSNHRGEHAESSAAL--TVLEEGLRIVEPLEDIETMEKKTVTFWCKVNRLNA- 6999

Query: 138  PNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195
              + W KNG+ + F+    ++ +D    +L+I+D    D G Y   A      ++ ++A 
Sbjct: 7000 -TLKWTKNGEEITFN-KRILYKIDKYKHSLIIKDCGFKDEGEYTVTAG-----QDKSVAE 7052

Query: 196  LKIHIKPY-LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD- 253
            L I   P   I   +D          F C++  +    V W R+  G  +  G+    + 
Sbjct: 7053 LLITEAPADFIEHLQDQTVTEFDDAVFTCQLSKEKA-SVKWYRN--GREIKEGKKYQFEK 7109

Query: 254  DGSLR---LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310
            DG+L    + +  L DE EYSC  ++      +   L V + P   + P     E+    
Sbjct: 7110 DGNLHRLIIKDCRLDDECEYSCGVDDR----KSRARLFVEEIPVEIIRPPQDVYEAPGAD 7165

Query: 311  RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
                    +    + W    N  II  G  + +  +      + V  I   D+ + R   
Sbjct: 7166 VIFMAELNKDGVEVKWL--RNNMIIIQG-DKHQMMSEGKVHRLQVCEIKPRDQGEYRFI- 7221

Query: 371  VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA 430
                   A     R KL + +      P I  G  N  + + +           P     
Sbjct: 7222 -------AKDKEARAKLELAA-----APRIKTGDQNLVVDVGNPLTMTVPYDAYPRAEAE 7269

Query: 431  WYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
            W    E+L        T+  T  + +  KSD G Y  V  ++H +         ++ IN 
Sbjct: 7270 WLKGEESLPTTTVDTTTDCTTFKIYEAKKSDKGRYKVVLRNKHAQ--------AEAFIN- 7320

Query: 491  NIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSG 550
                    +V  +PGP        + D  V L+W +    G S I+GY VE   R  +  
Sbjct: 7321 -------VEVIDVPGPVRNLEVTEIYDGEVGLAWQEPESDGGSKIIGYVVE---RRDI-- 7368

Query: 551  NNTPRNSRGWVVIARRVHQTHYVVKSLIP-GITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
                   + W+V+        Y V  L   G+ Y+F V   N  G   P      V    
Sbjct: 7369 -----KRKTWIVVTDHAENCEYTVTGLQKGGVEYLFRVSARNRVGTGEPVETERPV---- 7419

Query: 610  DSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFR 669
            ++ S +E  G   +               +E T ++     L WE   +     +  Y  
Sbjct: 7420 EAKSKFEVPGPPQN---------------VEVTDVNRFGRTLTWEAPEYDGGSPITGYVI 7464

Query: 670  PLDN-ITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLD 728
             L N  +I++E      ++++S   +T + +  +Y F +        GKPS+   A  + 
Sbjct: 7465 ELRNRASIKWEPTMTTGADELSAV-LTDVVENEEYFFRVRAQNMVGVGKPSHPTRAVKIT 7523

Query: 729  DVPDGPP--INIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN 786
            D  + P   IN++      T+V L W PP L+     I GY  ++   +   +K  +  N
Sbjct: 7524 DPIERPSGNINLDHSDQTKTSVQLTWEPP-LEDGGSPILGY--IIERKEEGTDK-WIRCN 7579

Query: 787  TTVHQATSLIMTNLTSGVSYSVQIAAETIIGL 818
              +  A +  +T L +G SY  +++AE   G+
Sbjct: 7580 PKLVPACAFKVTGLKAGSSYYYRVSAENAAGV 7611



 Score = 76.2 bits (179), Expect = 5e-12
 Identities = 114/450 (25%), Positives = 172/450 (38%), Gaps = 58/450 (12%)

Query: 77   HSDAGVY-WCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGS 135
            +SDAG Y +    N        NA     +++E   L+P + +S +       C    G 
Sbjct: 2939 YSDAGEYTFVAGRNRSSVVLYVNAPEPPQIIQE---LQPTTVESGKPARF---CAIISGK 2992

Query: 136  PEPNVYWKKNGQTLLFDGDSR-MHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194
            P+P V W K+ Q L      + +H      L++ +    D+  Y C A+N  G   ++ A
Sbjct: 2993 PQPKVSWYKDDQQLSPGFKCKFLHDAQEYTLLLIETFPEDSAVYTCEAKNDYGVATTS-A 3051

Query: 195  TLKIHIK-------------PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
            +L + I              P +I    D V   G S  FQCRV G  L    + +    
Sbjct: 3052 SLSVEIPEVVSPELEVPVYPPAVIVPLRDAVTSEGQSARFQCRVTGTDLKVSWYSKDREI 3111

Query: 242  GNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI----- 295
                  R+   +D   L +      DEG Y+  A NSVG V+++  L +  P  I     
Sbjct: 3112 KPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNSVGQVTSTAILKLEAPEKIMYEKL 3171

Query: 296  --------NLSP------NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341
                     ++P        + V   +VA+FTC     P     W   G    I+ G   
Sbjct: 3172 EEEIEMEVKVAPILRRRLEPLEVAVNHVAKFTCEVETTPNVKFQWYKAGRE--IYDG--- 3226

Query: 342  DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401
            DKY   +  + ++ L I      D      C A N  GS      LTVT     PP  I 
Sbjct: 3227 DKYSIRS-SNYLSTLEIPRPQVVDC-GEYSCKASNQHGSVSSTAFLTVT----EPPRFIK 3280

Query: 402  NGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN----VTNDGTLVLKDL 457
               S++ +       + C    +PE  + WY +GE  I    +     V +   L + +L
Sbjct: 3281 KLDSSRLVKQHDSTRYECKVGGSPEIKVTWY-KGETEIHPSEKYSMSFVDSVAVLEMHNL 3339

Query: 458  DKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
               DSG Y+C A +  G    S +L V +P
Sbjct: 3340 SVEDSGDYSCEAQNPAGSASTSTSLKVKAP 3369



 Score = 66.9 bits (156), Expect = 3e-09
 Identities = 109/462 (23%), Positives = 185/462 (40%), Gaps = 43/462 (9%)

Query: 44   RWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103
            +W K GV + S T +  +    L    +       DA  Y   A    G A S +ATL+V
Sbjct: 2727 KWLKNGVEIKS-TDKCQIRTKKLTHSLSIRNVHFGDAAEYSFVA----GKAAS-SATLYV 2780

Query: 104  AVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG 163
                 EFR   +  +  +    + EC      P+  V W K+GQ L   GD RM +    
Sbjct: 2781 EARHIEFRKHIKDIKVVEKKRAIFEC--EISEPDVQVQWMKDGQELQI-GD-RMKIQREK 2836

Query: 164  ---NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVT 220
                L+I   + +DAG+Y  +A     +    +    + I+   I     V+ +  + + 
Sbjct: 2837 YVHRLIIPSTKMSDAGQYTVVAGGNTSSANLIVEGRDVRIRS--IRKEIQVIERQRAEIE 2894

Query: 221  FQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGSLRLDNVI---LADEGEYSCEAEN 276
            F+  V  D + +  W +     N     R   + +  +   ++     +D GEY+  A  
Sbjct: 2895 FE--VNEDDI-EPQWYKDGIEINFHYEERYSYVVERRIHRMSIFETTYSDAGEYTFVAGR 2951

Query: 277  SVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF 336
            +  +V    Y+   +PP I        VESG  ARF    +G+P+P + W  +  +  + 
Sbjct: 2952 NRSSVVL--YVNAPEPPQIIQELQPTTVESGKPARFCAIISGKPQPKVSWYKDDQQ--LS 3007

Query: 337  PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP 396
            PG      H    +   T+L I +T   DS     C A N  G +     L+V   +   
Sbjct: 3008 PGFKCKFLHDAQEY---TLLLI-ETFPEDSA-VYTCEAKNDYGVATTSASLSVEIPEVVS 3062

Query: 397  PPI-ITNGPSNQTLPIK-------SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN 448
            P + +   P    +P++         A F C    T +  ++WY +   +  +    +T 
Sbjct: 3063 PELEVPVYPPAVIVPLRDAVTSEGQSARFQCRVTGT-DLKVSWYSKDREIKPSRFFRMTQ 3121

Query: 449  -DGT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
             + T  L + +    D GTYT VAS+  G+   +  L +++P
Sbjct: 3122 FEDTYQLEIAEAYPEDEGTYTFVASNSVGQVTSTAILKLEAP 3163



 Score = 64.5 bits (150), Expect = 2e-08
 Identities = 48/181 (26%), Positives = 85/181 (46%), Gaps = 13/181 (7%)

Query: 110  FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVI 167
            F L+P S + +QG T   + L   G P P  YW  NGQ ++ D   ++ + + G  +L+I
Sbjct: 1187 FVLKPTSVKCSQGQTARFD-LKVVGRPMPETYWFHNGQQVVNDYTHKIVIKEDGTQSLII 1245

Query: 168  QDARQTDAGRYQCIARNAAGTRESAIATLKIH-----IKPYLITGPEDVVAQTGSSVTFQ 222
              A   D+G +  IA+N AG + S   TL +      ++P  +    +V  + GS +   
Sbjct: 1246 VPAMPEDSGEWAVIAQNRAG-KASVSVTLSVEAKEDLVRPRFVERLRNVSVKEGSRLHMA 1304

Query: 223  CRVGGDPLPDVLWRRSAG---GGNMPLGRVK-VLDDGSLRLDNVILADEGEYSCEAENSV 278
             +  G+P PD++W +++        P  R++      +L +++    D   Y+  A N  
Sbjct: 1305 VKATGNPNPDIVWLKNSDIIVPHKYPRIRIEGTKGAAALNIESTARQDAAWYTATAINKA 1364

Query: 279  G 279
            G
Sbjct: 1365 G 1365



 Score = 62.9 bits (146), Expect = 5e-08
 Identities = 114/469 (24%), Positives = 175/469 (37%), Gaps = 55/469 (11%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            PY   +  D +       TL C    S    ++WYK G  +V+ +  SI    GL  +  
Sbjct: 5900 PYFTVKLQDYSALEKDDITLQCEL--SKDVPVKWYKDGEELVASSRISI-KTDGLRRILT 5956

Query: 72   THGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
                   D GVY C    S GT ++  N  +   +++ E  L     +   G+T   E  
Sbjct: 5957 IKKATEGDKGVYEC----SCGTDKTNCNIGVEPRLIKVERPLY--GVEVFVGETARFEI- 6009

Query: 131  PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGT 188
                 P+ +  WK  G+TL    +  + + DG    L++   R    G     A NA   
Sbjct: 6010 -EISEPDVHPIWKLKGETLTPSPECEI-IEDGKKHILILHQGRLDMTGEVSFQAANA--- 6064

Query: 189  RESAIATLKIHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
               + A LK+   P +   P  DV         F+C V  +P     W +       P  
Sbjct: 6065 --KSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGTQEIT-PDE 6120

Query: 248  RVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP-NSVN 303
            R +++ DG+   L + +V   DE +Y  EAE+       S  L +       ++P   V 
Sbjct: 6121 RFEIISDGTKHALIIKSVAFDDEAKYMFEAEDK----RTSAKLIIEGIRLKFITPLKDVT 6176

Query: 304  VESGNVARFTCTATGRPEPTMFWSVEGN-RTIIFPGMSRD-KYHATAVFDGVTVLTINDT 361
             +    A FT   +    P +++  +    T     M+ D K+H   + D    LTI+DT
Sbjct: 6177 KKERETAVFTVELSHENIPVVWFKNDQRLHTSKVVSMTDDGKFHTLTIKD----LTIDDT 6232

Query: 362  DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
             +           V   G S    KLTV   D    P  T    + T   K   +  C  
Sbjct: 6233 SQ---------IRVEAMGKSS-EAKLTVLEGD----PYFTGKLQDYTAVEKDEVILQCEI 6278

Query: 422  ICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTC 467
                 P+  W  +G+ +  +    +  DG    L+LK   K D G YTC
Sbjct: 6279 SKADAPV-KWMKDGKPITPSKNVVIKADGKKRILILKKALKKDIGQYTC 6326



 Score = 60.9 bits (141), Expect = 2e-07
 Identities = 53/206 (25%), Positives = 84/206 (40%), Gaps = 13/206 (6%)

Query: 201  KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW-RRSAGGGNMPLGRVKVLDDG--SL 257
            KP  +  P  V    G +  F  +V G P+P+  W        N    ++ + +DG  SL
Sbjct: 1184 KPVFVLKPTSVKCSQGQTARFDLKVVGRPMPETYWFHNGQQVVNDYTHKIVIKEDGTQSL 1243

Query: 258  RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP-----PSINLSPNSVNVESGNVARF 312
             +   +  D GE++  A+N  G  S S  L+V        P       +V+V+ G+    
Sbjct: 1244 IIVPAMPEDSGEWAVIAQNRAGKASVSVTLSVEAKEDLVRPRFVERLRNVSVKEGSRLHM 1303

Query: 313  TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
               ATG P P + W ++ +  I+     R +   T    G   L I  T + D+      
Sbjct: 1304 AVKATGNPNPDIVW-LKNSDIIVPHKYPRIRIEGT---KGAAALNIESTARQDAA-WYTA 1358

Query: 373  SAVNYAGSSFVRGKLTVTSDDDRPPP 398
            +A+N AG    R K+ V  +   P P
Sbjct: 1359 TAINKAGRDTTRCKVNVEVEHAEPEP 1384



 Score = 58.0 bits (134), Expect = 1e-06
 Identities = 105/481 (21%), Positives = 182/481 (37%), Gaps = 54/481 (11%)

Query: 13   YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRAT 72
            Y + +P  + V     AT   + GG P P ++W KG    ++   R I+   G       
Sbjct: 4426 YFVSEPQSIKVMEKTVATFIAKVGGDPIPNVKWMKGKWRQLNQGGRIIIQQRGDEAKLEI 4485

Query: 73   HGRVHSDAGVYWCEATNSYGTARSRNATLHV-----AVLREEFRLE----PESKQSAQGD 123
                 +D+G+Y C A N +G    R+  L V      V+ E+ R +    P  K+  +  
Sbjct: 4486 KDTTKTDSGLYKCVAFNQHGEI-ERSVNLQVEERKQEVVEEDVRGKLKRIPTKKKEDEEQ 4544

Query: 124  TV-VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
            T+ +LE L      E   Y +  G T     D R  L+    L ++  R+ ++ R +   
Sbjct: 4545 TIDILELLKNVDPKEYEKYARMYGIT-----DFR-GLLQAFEL-LKQTREEESHRLEIEL 4597

Query: 183  RNAAGTRESAIATLKIHIKPYLI-TGP-------EDVVAQTGSSVTFQCRVG-GDPLPDV 233
               A   +     L   I+  L  T P       E+    T     F+C +    P   +
Sbjct: 4598 TEKAQKEDQEFEELVAFIQQRLTQTEPVTLIRDIENQTVLTDEDAIFECEIKINYPEIKL 4657

Query: 234  LWRRSAGG-GNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
             W +      +    ++K+  D   L++ N  L D+G Y        G   AS  LTV +
Sbjct: 4658 SWYKGTQKLDSSDKYKIKIEGDRHILKIKNCQLEDQGNYRIVC----GPHIASARLTVIE 4713

Query: 292  PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
             P++    +    + GN    +C  +  P     W   G R I   G      ++T V D
Sbjct: 4714 -PAVERHLHDTTFKEGNTCTLSCQFS-IPNAKSQWYRNG-RPIKIGGR-----YSTQVSD 4765

Query: 352  GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
             V  L I D  + + +    C   N   ++     LT+ ++    P   T    N  +  
Sbjct: 4766 KVHKLIIKDV-RTEDQGQYTCKLDNLETTA----DLTIEAE----PIQFTKSIQNIVVSE 4816

Query: 412  KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCV 468
               A F C  +   + ++ WY     L ++ + +  ++G    + + ++   D G Y+ +
Sbjct: 4817 HQSATFEC-EVSFDDAVVTWYKGPTELTESPKYSFRSEGRCHYMTIHNVTAEDEGVYSVI 4875

Query: 469  A 469
            A
Sbjct: 4876 A 4876



 Score = 56.8 bits (131), Expect = 3e-06
 Identities = 107/439 (24%), Positives = 165/439 (37%), Gaps = 48/439 (10%)

Query: 43   IRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLH 102
            ++W+K G+  +      I+  G    L  +   +  D   Y CEA     TAR+      
Sbjct: 6642 VKWFKDGI-EIEKAEYDIISKGAERILVISKC-LFDDEAEYACEAK----TARTSGL--- 6692

Query: 103  VAVLREE--FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV 160
            + V+ EE  F       +  + +TV L C      P   V W K G   + DG    ++ 
Sbjct: 6693 LTVIEEEAVFTKNLHDLEVNENETVRLIC--EISKPNAEVTWFK-GDEEVPDGGRFEYIS 6749

Query: 161  DGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSS 218
            DG    LVI++A   DAG+Y C   +++ T +  +  L        +T P+++    G  
Sbjct: 6750 DGRKRILVIRNAHPEDAGKYTCKLPSSSTTGKLTVHELAAE----FLTRPQNLEVLEGDK 6805

Query: 219  VTFQCRVGGDPLP-DVLWRRSAGGGNMPLGRVKVLDDGSLR---LDNVILADEGEYSCEA 274
              F C V  + +    LW  +      P  +  ++ DG  R   + + ++ D G+Y+   
Sbjct: 6806 AEFACSVSKEAITVQWLWGDTV---LEPGDKYDIISDGKKRTLVVKDSVVGDAGKYTV-- 6860

Query: 275  ENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334
               VG   A+  LTV +      S     V  G    F C          ++    N   
Sbjct: 6861 --MVGEAKATARLTVIEKTQDYNSLKDQEVNEGQEIIFNCEVNKEGAKEKWYK---NGEA 6915

Query: 335  IFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGS-SFVRGKLTVTSDD 393
            IF      KY      D V  L I DT   D + T   S  N+ G  +     LTV  + 
Sbjct: 6916 IFDSA---KY-IIVQKDLVYTLRIRDTQLKD-QATYSISLSNHRGEHAESSAALTVLEEG 6970

Query: 394  DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND---G 450
             R   I+      +T+  K    F C  +      + W   GE +  N R     D    
Sbjct: 6971 LR---IVEPLEDIETME-KKTVTFWC-KVNRLNATLKWTKNGEEITFNKRILYKIDKYKH 7025

Query: 451  TLVLKDLDKSDSGTYTCVA 469
            +L++KD    D G YT  A
Sbjct: 7026 SLIIKDCGFKDEGEYTVTA 7044



 Score = 54.4 bits (125), Expect = 2e-05
 Identities = 35/129 (27%), Positives = 59/129 (45%), Gaps = 7/129 (5%)

Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA---GGGNMPLGRVKVLDD-GSLRLDNVIL 264
           + VVA  GS+ TF+  + G P+P+V W R         +P  ++   D    L + +V  
Sbjct: 13  QSVVALEGSAATFEAHISGFPVPEVSWYRDGQVLSAATLPGVQISFSDGRAKLVIPSVTE 72

Query: 265 ADEGEYSCEAENSVGAVSASGYLTV---YDPPSINLSPNSVNVESGNVARFTCTATGRPE 321
           A+ G Y+ +A N  G  +++  L V     PP+ +    S+    G+  R     TG P 
Sbjct: 73  ANSGRYTIQATNGSGQATSTAELLVTAGTAPPNFSQRLQSMTARQGSQVRLDVRVTGIPT 132

Query: 322 PTMFWSVEG 330
           P + +  +G
Sbjct: 133 PVVKFYRDG 141



 Score = 54.4 bits (125), Expect = 2e-05
 Identities = 51/211 (24%), Positives = 77/211 (36%), Gaps = 14/211 (6%)

Query: 271  SCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
            SC     +          +Y P  + L P SV    G  ARF     GRP P  +W   G
Sbjct: 1164 SCSPARRLDETDEGQLERLYKPVFV-LKPTSVKCSQGQTARFDLKVVGRPMPETYWFHNG 1222

Query: 331  NRTIIFPGMSRDKYHATAV-FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389
             + +       D  H   +  DG   L I      DS    V  A N AG + V   L+V
Sbjct: 1223 QQVV------NDYTHKIVIKEDGTQSLIIVPAMPEDSGEWAVI-AQNRAGKASVSVTLSV 1275

Query: 390  TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND 449
             + +D   P       N ++   S       A   P P I W    + ++ +    +  +
Sbjct: 1276 EAKEDLVRPRFVERLRNVSVKEGSRLHMAVKATGNPNPDIVWLKNSDIIVPHKYPRIRIE 1335

Query: 450  GT-----LVLKDLDKSDSGTYTCVASSRHGK 475
            GT     L ++   + D+  YT  A ++ G+
Sbjct: 1336 GTKGAAALNIESTARQDAAWYTATAINKAGR 1366



 Score = 50.4 bits (115), Expect = 3e-04
 Identities = 47/164 (28%), Positives = 68/164 (41%), Gaps = 9/164 (5%)

Query: 134 GSPEPNVYWKKNGQTLLFDG--DSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRE 190
           G P P V W ++GQ L        ++   DG   LVI    + ++GRY   A N +G   
Sbjct: 31  GFPVPEVSWYRDGQVLSAATLPGVQISFSDGRAKLVIPSVTEANSGRYTIQATNGSGQAT 90

Query: 191 SAIATLKIH--IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
           S    L       P      + + A+ GS V    RV G P P V + R  G        
Sbjct: 91  STAELLVTAGTAPPNFSQRLQSMTARQGSQVRLDVRVTGIPTPVVKFYRD-GVEIQSSPD 149

Query: 249 VKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
            ++L +G   SL +      D G YS  A N+VG  +++  L +
Sbjct: 150 FQILQEGDLYSLIIAEAYPEDSGTYSVNATNNVGRATSTAELLI 193



 Score = 50.0 bits (114), Expect = 4e-04
 Identities = 47/197 (23%), Positives = 83/197 (42%), Gaps = 10/197 (5%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-THRSILPAGGLFFLR 70
            P  + +P  V  ++ Q A  + +  G P P   W+  G  VV+D TH+ ++   G   L 
Sbjct: 1185 PVFVLKPTSVKCSQGQTARFDLKVVGRPMPETYWFHNGQQVVNDYTHKIVIKEDGTQSLI 1244

Query: 71   ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR---LEPESKQSAQGDTVVL 127
                 +  D+G +   A N  G A S + TL V    +  R   +E     S +  + + 
Sbjct: 1245 IVPA-MPEDSGEWAVIAQNRAGKA-SVSVTLSVEAKEDLVRPRFVERLRNVSVKEGSRLH 1302

Query: 128  ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL---VDGGNLVIQDARQTDAGRYQCIARN 184
              +   G+P P++ W KN   ++     R+ +        L I+   + DA  Y   A N
Sbjct: 1303 MAVKATGNPNPDIVWLKNSDIIVPHKYPRIRIEGTKGAAALNIESTARQDAAWYTATAIN 1362

Query: 185  AAGTRESAIATLKIHIK 201
             AG R++    + + ++
Sbjct: 1363 KAG-RDTTRCKVNVEVE 1378



 Score = 48.4 bits (110), Expect = 0.001
 Identities = 60/220 (27%), Positives = 93/220 (42%), Gaps = 18/220 (8%)

Query: 17  QPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75
           QPL   VA     AT      G P P + WY+ G ++ + T    LP   + F       
Sbjct: 10  QPLQSVVALEGSAATFEAHISGFPVPEVSWYRDGQVLSAAT----LPGVQISFSDGRAKL 65

Query: 76  V-----HSDAGVYWCEATNSYGTARSRNATLHVA-VLREEFRLEPESKQSAQGDTVVLEC 129
           V      +++G Y  +ATN  G A S    L  A      F    +S  + QG  V L+ 
Sbjct: 66  VIPSVTEANSGRYTIQATNGSGQATSTAELLVTAGTAPPNFSQRLQSMTARQGSQVRLD- 124

Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAG 187
           +   G P P V + ++G  +    D ++ L +G   +L+I +A   D+G Y   A N  G
Sbjct: 125 VRVTGIPTPVVKFYRDGVEIQSSPDFQI-LQEGDLYSLIIAEAYPEDSGTYSVNATNNVG 183

Query: 188 TRESAIATLKIHIKPYLITG--PEDVVAQTGSSVTFQCRV 225
            R ++ A L I  +   +     + +V+    S T Q R+
Sbjct: 184 -RATSTAELLIQGEEEAVPAKKTKTIVSTAQISQTRQARI 222



 Score = 48.4 bits (110), Expect = 0.001
 Identities = 32/91 (35%), Positives = 49/91 (53%), Gaps = 8/91 (8%)

Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKV---LDDG 255
           + P+ I  P       G S+ F+C+VGG+P P VLW++  GG  +  G R KV    + G
Sbjct: 825 VPPFFIRKPVVHKLIEGGSIIFECQVGGNPKPHVLWKK--GGVPLTTGYRYKVSYKRETG 882

Query: 256 SLRLD-NVILADE-GEYSCEAENSVGAVSAS 284
             +L+ ++  AD+ GEY+    N  G  SA+
Sbjct: 883 ECKLEISMTFADDAGEYTIVIRNKFGEASAT 913



 Score = 47.2 bits (107), Expect = 0.003
 Identities = 63/272 (23%), Positives = 97/272 (35%), Gaps = 23/272 (8%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPAG 64
            +T  E   +I    + TV   + A   C      P   + WYKG   + S     I   G
Sbjct: 4619 LTQTEPVTLIRDIENQTVLTDEDAIFECEIKINYPEIKLSWYKGTQKLDSSDKYKIKIEG 4678

Query: 65   GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
                L+  + ++  D G Y         +AR       + V+              +G+T
Sbjct: 4679 DRHILKIKNCQLE-DQGNYRIVCGPHIASAR-------LTVIEPAVERHLHDTTFKEGNT 4730

Query: 125  VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIAR 183
              L C      P     W +NG+ +   G     + D  + L+I+D R  D G+Y C   
Sbjct: 4731 CTLSC--QFSIPNAKSQWYRNGRPIKIGGRYSTQVSDKVHKLIIKDVRTEDQGQYTCKLD 4788

Query: 184  NAAGTRESAIATLKIHIKPYLIT-GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
            N   T     A L I  +P   T   +++V     S TF+C V  D      ++      
Sbjct: 4789 NLETT-----ADLTIEAEPIQFTKSIQNIVVSEHQSATFECEVSFDDAVVTWYKGPTELT 4843

Query: 243  NMPLGRVKVLDDGS---LRLDNVILADEGEYS 271
              P  +     +G    + + NV   DEG YS
Sbjct: 4844 ESP--KYSFRSEGRCHYMTIHNVTAEDEGVYS 4873



 Score = 46.8 bits (106), Expect = 0.004
 Identities = 28/90 (31%), Positives = 38/90 (42%), Gaps = 2/90 (2%)

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL-- 259
           P L+ G ++     G SVT +C + G P P V W R        +        G  RL  
Sbjct: 690 PTLVWGLKNKTVTEGESVTLECHISGHPQPTVTWYREDYKIESSMDFQITFKAGLARLVI 749

Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTV 289
                 D G ++C A N  G+VS S +L V
Sbjct: 750 REAFAEDSGRFTCTATNKAGSVSTSCHLHV 779



 Score = 46.0 bits (104), Expect = 0.006
 Identities = 28/88 (31%), Positives = 45/88 (51%), Gaps = 5/88 (5%)

Query: 115 ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQT 173
           ++K   +G++V LEC    G P+P V W +    +    D ++    G   LVI++A   
Sbjct: 697 KNKTVTEGESVTLEC-HISGHPQPTVTWYREDYKIESSMDFQITFKAGLARLVIREAFAE 755

Query: 174 DAGRYQCIARNAAGTRESAIATLKIHIK 201
           D+GR+ C A N AG   S   +  +H+K
Sbjct: 756 DSGRFTCTATNKAG---SVSTSCHLHVK 780



 Score = 45.6 bits (103), Expect = 0.008
 Identities = 82/377 (21%), Positives = 138/377 (36%), Gaps = 32/377 (8%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            PY   +  D T        L C    + +P ++W K G   ++ +   ++ A G   +  
Sbjct: 6255 PYFTGKLQDYTAVEKDEVILQCEISKADAP-VKWMKDGK-PITPSKNVVIKADGKKRILI 6312

Query: 72   THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
                +  D G Y C+      +A        + ++R  + +E    ++A+ D  + E   
Sbjct: 6313 LKKALKKDIGQYTCDCGTDQTSANLNIEDRDIEIIRPLYSVEVIETETARFDIEISE--- 6369

Query: 132  PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRE 190
                   +  WK  G+ L    D  +      + L + + R   AG     A NA   + 
Sbjct: 6370 ----EGVHGNWKLKGEPLTESPDCEIKEEGKKHFLTLYNVRLDQAGGVDFQAANA---KS 6422

Query: 191  SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250
             A   +K  +   L+   +DV    G S TF C +  + +P V W    G    P  +V 
Sbjct: 6423 GAHLRVKPRVIG-LLRPLKDVTVTAGESATFDCELSYEGIP-VEWYLQ-GKKLEPSDKVV 6479

Query: 251  VLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP-NSVNVES 306
               +G   +L L +V L D GE S  A++          L V +PP     P     VE 
Sbjct: 6480 TRAEGRAHTLILRDVKLTDAGEVSLTAKD----FRTQANLFVKEPPVEFTKPLEDQTVEE 6535

Query: 307  GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
               A   C  + R    + W   G        + + K +       V  L I+    +D+
Sbjct: 6536 EATAILECEVS-RENAKVKWFKNGEE------IHKTKKYDIISEGRVRKLIIHGCTLDDA 6588

Query: 367  RNTIVCSAVNYAGSSFV 383
            + T  C A ++  S F+
Sbjct: 6589 K-TYTCDAKDFKTSCFL 6604



 Score = 45.2 bits (102), Expect = 0.011
 Identities = 33/89 (37%), Positives = 45/89 (50%), Gaps = 8/89 (8%)

Query: 216  GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---RVKVLDDG--SLRLDNVILADEGEY 270
            G+ VTF C+  G PLP + W +   G  +  G    ++VL DG  SLRL  V+  DEG Y
Sbjct: 1049 GTGVTFHCKTTGYPLPKIAWYKD--GKRIRHGERYHMEVLQDGSASLRLPVVLPEDEGIY 1106

Query: 271  SCEAENSVGAVSASGYLTVYDPPSINLSP 299
            +  A N  G    S  L V +P +   +P
Sbjct: 1107 TVFASNMKGNAICSAKLYV-EPVAPTATP 1134



 Score = 44.8 bits (101), Expect = 0.015
 Identities = 47/198 (23%), Positives = 79/198 (39%), Gaps = 16/198 (8%)

Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGN--RTIIFPGMSRDKYHATAVF 350
           P+      SV    G+ A F    +G P P + W  +G        PG+        +  
Sbjct: 6   PTFTQPLQSVVALEGSAATFEAHISGFPVPEVSWYRDGQVLSAATLPGVQ------ISFS 59

Query: 351 DGVTVLTIND-TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409
           DG   L I   T+ N  R TI   A N +G +    +L VT+     PP  +    + T 
Sbjct: 60  DGRAKLVIPSVTEANSGRYTI--QATNGSGQATSTAELLVTAGT--APPNFSQRLQSMTA 115

Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYT 466
              S           P P++ +Y +G  +  +    +  +G   +L++ +    DSGTY+
Sbjct: 116 RQGSQVRLDVRVTGIPTPVVKFYRDGVEIQSSPDFQILQEGDLYSLIIAEAYPEDSGTYS 175

Query: 467 CVASSRHGKYVWSGALLV 484
             A++  G+   +  LL+
Sbjct: 176 VNATNNVGRATSTAELLI 193



 Score = 44.8 bits (101), Expect = 0.015
 Identities = 28/87 (32%), Positives = 36/87 (41%), Gaps = 2/87 (2%)

Query: 22  TVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAG 81
           TV   +  TL C   G P P + WY+    + S     I    GL  L         D+G
Sbjct: 700 TVTEGESVTLECHISGHPQPTVTWYREDYKIESSMDFQITFKAGLARL-VIREAFAEDSG 758

Query: 82  VYWCEATNSYGTARSRNATLHVAVLRE 108
            + C ATN  G+  S +  LHV V  E
Sbjct: 759 RFTCTATNKAGSV-STSCHLHVKVSEE 784



 Score = 39.9 bits (89), Expect = 0.41
 Identities = 84/327 (25%), Positives = 123/327 (37%), Gaps = 41/327 (12%)

Query: 15   IEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFLRAT 72
            I +PL D+TVA  Q A   C    +P    +W K G  L ++D +R+     G+      
Sbjct: 2349 ISKPLADLTVAESQRAVFECEVA-NPESEGQWLKNGKPLPMTDQYRA--ETDGVKRRLNI 2405

Query: 73   HGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
                  D G Y      SY  A S+ +A LHV  ++ +  L+  +    Q     +E   
Sbjct: 2406 PAAKMDDMGEY------SYEIASSKTSAKLHVEAVKIKKTLKNLTVTETQEAVFSVELSH 2459

Query: 132  PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGTR 189
            P         W KNG  L    D     V G    L I+    TD   Y           
Sbjct: 2460 P---DVKGALWIKNGVELE-SNDKYEISVKGTVHTLKIKHCVVTDESVYSFKLGKIGANA 2515

Query: 190  ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL--- 246
               + T+KI      I  P+DV A   + V+F+  V  D +P V W       N+ L   
Sbjct: 2516 RLHVETVKI------IKKPKDVTALENAVVSFELSVSHDTVP-VRWFHK----NVELKQS 2564

Query: 247  GRVKVLDD---GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
             + K++       L L N+  AD GEY+      VG +     L V +   I  +  S+ 
Sbjct: 2565 DKYKMISQRKVHKLMLHNISPADAGEYTA----FVGQLECKAKLFV-ETIHITKTMKSIE 2619

Query: 304  VESGNVARFTCTATGRPEPTMFWSVEG 330
            +     A F C  +    P++ W   G
Sbjct: 2620 IPETKTASFQCEVSHFNVPSV-WLKNG 2645



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 21/81 (25%), Positives = 36/81 (44%), Gaps = 3/81 (3%)

Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLV 453
           PP +  G  N+T+         C     P+P + WY E   +  +    +T       LV
Sbjct: 689 PPTLVWGLKNKTVTEGESVTLECHISGHPQPTVTWYREDYKIESSMDFQITFKAGLARLV 748

Query: 454 LKDLDKSDSGTYTCVASSRHG 474
           +++    DSG +TC A+++ G
Sbjct: 749 IREAFAEDSGRFTCTATNKAG 769



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 85/362 (23%), Positives = 135/362 (37%), Gaps = 43/362 (11%)

Query: 121  QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV---DGGNLVIQDARQTDAGR 177
            +GD V LE      + E    W K+G  +      R+H+V       L+I+DA Q D+G 
Sbjct: 2096 EGDIVQLEVKVSVENVEG--VWMKDGHEI--QSSDRIHIVLDKQSHMLLIEDATQEDSGT 2151

Query: 178  YQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
            Y   + +  G   S    + ++    +I   +DV    G+    +C+V    +    W  
Sbjct: 2152 Y---SFSIPGLELSTTGQVTVY-SVEIIVPLKDVHVVEGTKAILECKVSAPDVTSSKWYL 2207

Query: 238  SAGGGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
            +      P  RV+ +  G+   L +     +DEG Y       VG V  S  +TV +   
Sbjct: 2208 N-DHQIKPDERVQAVCKGTKQRLVITRTHASDEGHYKL----MVGKVETSCNVTVEEIEI 2262

Query: 295  INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
            I    +    E+ NV+ F           + W  +G      P   + K  A      +T
Sbjct: 2263 IRGLHDITCTETQNVS-FE-VELSHSGIDVIWHFKGQEIKAGP---KYKIEARGKIYKLT 2317

Query: 355  VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
            V+ +   D+ +         V YAG     GKL V          I+   ++ T+     
Sbjct: 2318 VVKMMKDDEGE--------YVFYAGGKKTSGKLIVAGG------AISKPLADLTVAESQR 2363

Query: 415  AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTC-VAS 470
            AVF C  +  PE    W   G+ L    +     DG    L +      D G Y+  +AS
Sbjct: 2364 AVFEC-EVANPESEGQWLKNGKPLPMTDQYRAETDGVKRRLNIPAAKMDDMGEYSYEIAS 2422

Query: 471  SR 472
            S+
Sbjct: 2423 SK 2424



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 29/109 (26%), Positives = 42/109 (38%), Gaps = 10/109 (9%)

Query: 501  SSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGW 560
            +++P PP      N T   + L+W      G + I GY VE             R +  W
Sbjct: 7822 ATVPDPPENVKWRNPTSKGIFLTWEPPKYDGGARIKGYLVE----------KCQRGTDKW 7871

Query: 561  VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
             +    V +T   V  L  G  Y + V+  N  G S PS  +D +   D
Sbjct: 7872 EICGEPVIETKMEVTKLKEGEWYAYRVKALNRIGASKPSKPTDDIQAID 7920



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 27/78 (34%), Positives = 36/78 (46%), Gaps = 5/78 (6%)

Query: 417  FPCTAICTPEPIIAWYFEGEALIQNHR--RNVTNDG--TLVLKDLDKSDSGTYTCVASSR 472
            F C     P P IAWY +G+ +    R    V  DG  +L L  +   D G YT  AS+ 
Sbjct: 1054 FHCKTTGYPLPKIAWYKDGKRIRHGERYHMEVLQDGSASLRLPVVLPEDEGIYTVFASNM 1113

Query: 473  HGKYVWSGALLVDSPINP 490
             G  + S  L V+ P+ P
Sbjct: 1114 KGNAICSAKLYVE-PVAP 1130



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 32/112 (28%), Positives = 55/112 (49%), Gaps = 11/112 (9%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAG--GSPSPAIRW-YKGGVLVVSDTHRSILPAGGL 66
            + P+  ++   + + +  PA   CR    G P+  + W + G  L  ++  R I   G  
Sbjct: 1429 QKPFFKKKLTSLRLKQFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFG-- 1486

Query: 67   FFLRATHGRVHS-DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK 117
             +    +G  +S D+GV  C ATN YGT  + +ATL   ++++E  L  ES+
Sbjct: 1487 -YCSLDYGVAYSRDSGVITCRATNKYGTDHT-SATL---IVKDEKSLVEESQ 1533



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 29/83 (34%), Positives = 37/83 (44%), Gaps = 3/83 (3%)

Query: 201  KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLD 260
            KP L+  PE      G +  F+CRV G PLP V W  ++        R ++  DG   LD
Sbjct: 1568 KPELVLVPEPARVLEGETARFRCRVTGYPLPKVNWYLNSQLIRKS-KRFRLRYDGIHYLD 1626

Query: 261  NVILA--DEGEYSCEAENSVGAV 281
             V     D GE    AEN  G +
Sbjct: 1627 IVDCKSYDTGEVKVTAENPEGFI 1649



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 52/226 (23%), Positives = 81/226 (35%), Gaps = 7/226 (3%)

Query: 8    SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGL 66
            S EAP I E+    TVA+   A    R  G P P  +W++ GV +  +D      P   +
Sbjct: 1801 SMEAPKIFERIQSQTVAQGTDAHFRVRVVGKPDPECQWFRNGVQIERTDRIYWYWPEDNV 1860

Query: 67   FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV- 125
              L         D+     +A N  G   S    L  A     F    +   + + D++ 
Sbjct: 1861 CEL-VIRDVTADDSASIMVKAVNIAGETSSHAFLLVQAKQLISFIQNLQDVVAKERDSMA 1919

Query: 126  VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARN 184
              EC      P   V W KNG  +      RMH     + L +     +DA  Y C    
Sbjct: 1920 TFEC--ETSEPFIKVKWFKNGIEIHSGEKYRMHSDRKAHFLSVLAVEMSDADDYSCALVE 1977

Query: 185  AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPL 230
                + +A   ++  +  + I   EDV      +   +C V  + +
Sbjct: 1978 DESVKTTAKLIVEGAVVEF-IKELEDVEVPESFTGELECEVSPEDI 2022



 Score = 37.5 bits (83), Expect = 2.2
 Identities = 28/109 (25%), Positives = 50/109 (45%), Gaps = 4/109 (3%)

Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM-HLVDGG--NLV 166
           F  +P   +  +G +++ EC    G+P+P+V WKK G  L      ++ +  + G   L 
Sbjct: 829 FIRKPVVHKLIEGGSIIFEC-QVGGNPKPHVLWKKGGVPLTTGYRYKVSYKRETGECKLE 887

Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT 215
           I      DAG Y  + RN  G   + ++ L+       I   ++++ QT
Sbjct: 888 ISMTFADDAGEYTIVIRNKFGEASATVSLLEEADYEAYIKSQQEMMYQT 936



 Score = 37.1 bits (82), Expect = 2.9
 Identities = 64/286 (22%), Positives = 106/286 (37%), Gaps = 23/286 (8%)

Query: 291  DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
            + P I     S  V  G  A F     G+P+P   W   G +         D+ +     
Sbjct: 1803 EAPKIFERIQSQTVAQGTDAHFRVRVVGKPDPECQWFRNGVQI-----ERTDRIYWYWPE 1857

Query: 351  DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
            D V  L I D   +DS  +I+  AVN AG +     L V +   +    I N        
Sbjct: 1858 DNVCELVIRDVTADDSA-SIMVKAVNIAGETSSHAFLLVQA--KQLISFIQNLQDVVAKE 1914

Query: 411  IKSMAVFPCTAICTPEPII--AWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTY 465
              SMA F C    T EP I   W+  G  +    +  + +D     L +  ++ SD+  Y
Sbjct: 1915 RDSMATFECE---TSEPFIKVKWFKNGIEIHSGEKYRMHSDRKAHFLSVLAVEMSDADDY 1971

Query: 466  TCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWS 525
            +C A         +  L+V+  +   + F +  +   +P   T  +   V+   +   W 
Sbjct: 1972 SC-ALVEDESVKTTAKLIVEGAV---VEFIKELEDVEVPESFTGELECEVSPEDIEGKWY 2027

Query: 526  QNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRG---WVVIARRVH 568
              +   SS+          R  L+  +  ++ +G   +VV  +R H
Sbjct: 2028 HGDVELSSNHKYVLASRRGRRILTIKDVNKDDQGEYSFVVDGKRTH 2073



 Score = 36.3 bits (80), Expect = 5.1
 Identities = 27/97 (27%), Positives = 47/97 (48%), Gaps = 7/97 (7%)

Query: 724  AQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVV-NWLDVPANKSM 782
            A++  +VP GPP N+E+  +N     L W  PE       ITGY + + N   +    +M
Sbjct: 7421 AKSKFEVP-GPPQNVEVTDVNRFGRTLTWEAPEYD-GGSPITGYVIELRNRASIKWEPTM 7478

Query: 783  VAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819
                TT     S ++T++     Y  ++ A+ ++G+G
Sbjct: 7479 ----TTGADELSAVLTDVVENEEYFFRVRAQNMVGVG 7511



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 43/194 (22%), Positives = 79/194 (40%), Gaps = 16/194 (8%)

Query: 142  WKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIAR--NAAGTRESAIATLK 197
            W K+G  +  +      + DG +  L I D + +DAG Y C+ R  N   T  + +   +
Sbjct: 5389 WMKDGSNIR-ESPKHKFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLIVEE 5447

Query: 198  IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA-----GGGNMPLGRVKVL 252
            + ++ ++ T  E+V    G  +   C +  +    V+WRR         G   LG + + 
Sbjct: 5448 LPVR-FVKTLEEEVTVVKGQPLYLTCELNKE--RSVVWRRDGKIIKDKPGKFALGIIGL- 5503

Query: 253  DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARF 312
               SL + +   +D G Y+   E+S  + S+   +       +       +V+    A F
Sbjct: 5504 -SHSLTITDSDDSDAGTYTVTVEDSELSCSSCVKVVEVIRDWLVKPIRDQHVKPKGTATF 5562

Query: 313  TCTATGRPEPTMFW 326
            TC    +  P + W
Sbjct: 5563 TCDIV-KDTPNIKW 5575


>UniRef50_P20241 Cluster: Neuroglian precursor; n=17;
           Endopterygota|Rep: Neuroglian precursor - Drosophila
           melanogaster (Fruit fly)
          Length = 1302

 Score =  154 bits (374), Expect = 1e-35
 Identities = 173/633 (27%), Positives = 253/633 (39%), Gaps = 75/633 (11%)

Query: 27  QPATLNCRA-GGSPSPAIRWY-----KGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
           +P  L C A  G PSP + W       G +  ++++  ++ P G L+F   T     SD 
Sbjct: 149 EPFMLKCAAPDGFPSPTVNWMIQESIDGSIKSINNSRMTLDPEGNLWFSNVTREDASSDF 208

Query: 81  GVYWCEATNSYGTA-RSRNATL----HVAVLREEFRLEP-----ESKQSA--QGDTVVLE 128
             Y C AT+ + +  +  N  L     + V   + +  P       +QS   +G  + L 
Sbjct: 209 -YYACSATSVFRSEYKIGNKVLLDVKQMGVSASQNKHPPVRQYVSRRQSLALRGKRMELF 267

Query: 129 CLPPRGSPEPNVYWKKNGQTLLF-DGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
           C+   G+P P   W K+GQ + + D  ++ H   G +LVI+     DAG Y C   N  G
Sbjct: 268 CIYG-GTPLPQTVWSKDGQRIQWSDRITQGHY--GKSLVIRQTNFDDAGTYTCDVSNGVG 324

Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG--GGNMP 245
             +S    L ++  PY    PE   A     V F+CR  G P P + W  +      + P
Sbjct: 325 NAQSFSIILNVNSVPYFTKEPEIATAAEDEEVVFECRAAGVPEPKISWIHNGKPIEQSTP 384

Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-DPPSINLSPNSVNV 304
             R + + D ++R+ N++  D G Y C A NS+G V    YL V  +PP+I+ +P +V+ 
Sbjct: 385 NPR-RTVTDNTIRIINLVKGDTGNYGCNATNSLGYVYKDVYLNVQAEPPTISEAPAAVST 443

Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
             G      C   G P+P + W    N       ++  +Y+  A  D    L I D   +
Sbjct: 444 VDGRNVTIKCRVNGSPKPLVKWLRASN------WLTGGRYNVQANGD----LEIQDVTFS 493

Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI-- 422
           D+     C A N  G     G L V  +  R    IT  P N  +     A F C     
Sbjct: 494 DA-GKYTCYAQNKFGEIQADGSL-VVKEHTR----ITQEPQNYEVAAGQSATFRCNEAHD 547

Query: 423 CTPEPIIAWYFEGEAL-IQNHRRNV-TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
            T E  I W+ +G+++  +   R V TND +L +    + DSG YTCVA +R  +     
Sbjct: 548 DTLEIEIDWWKDGQSIDFEAQPRFVKTNDNSLTIAKTMELDSGEYTCVARTRLDEATARA 607

Query: 481 ALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQV 540
            L+V     PN              P    IT       +   W Q      S IL Y +
Sbjct: 608 NLIVQDV--PN-------------APKLTGITCQADKAEI--HWEQQGD-NRSPILHYTI 649

Query: 541 EVFSRETLSGNNTPRNSRGWVVIARRVHQT-HYVVKSLIPGITYMFIVRTENSHGLSGPS 599
           +          NT      W     +V  T    V  + P   Y F V   N  G S PS
Sbjct: 650 QF---------NTSFTPASWDAAYEKVPNTDSSFVVQMSPWANYTFRVIAFNKIGASPPS 700

Query: 600 PVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILT 632
             SDS T   D         V   TE  N +++
Sbjct: 701 AHSDSCTTQPDVPFKNPDNVVGQGTEPNNLVIS 733



 Score =  123 bits (297), Expect = 3e-26
 Identities = 124/479 (25%), Positives = 189/479 (39%), Gaps = 37/479 (7%)

Query: 28  PATLNCRAGGSPSPAIRWYKGGVLVVSDTHRS-ILPAGGLFFLRATHGRVHSDAGVYWCE 86
           P  + C A G P P   W K G       + + +L   G   L  T  +   D G Y C 
Sbjct: 54  PFIIECEADGQPEPEYSWIKNGKKFDWQAYDNRMLRQPGRGTLVITIPK-DEDRGHYQCF 112

Query: 87  ATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW---K 143
           A+N +GTA S +  +  A L        ++ ++ +G+  +L+C  P G P P V W   +
Sbjct: 113 ASNEFGTATSNSVYVRKAELNAFKDEAAKTLEAVEGEPFMLKCAAPDGFPSPTVNWMIQE 172

Query: 144 KNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR---YQCIARNAAGTRESAIATLKIHI 200
               ++    +SRM L   GNL   +  + DA     Y C A +   +       + + +
Sbjct: 173 SIDGSIKSINNSRMTLDPEGNLWFSNVTREDASSDFYYACSATSVFRSEYKIGNKVLLDV 232

Query: 201 KPYLITGPED-------------VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
           K   ++  ++              +A  G  +   C  GG PLP  +W +  G       
Sbjct: 233 KQMGVSASQNKHPPVRQYVSRRQSLALRGKRMELFCIYGGTPLPQTVWSKD-GQRIQWSD 291

Query: 248 RVKVLDDG-SLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSPNSVNVE 305
           R+     G SL +      D G Y+C+  N VG A S S  L V   P     P      
Sbjct: 292 RITQGHYGKSLVIRQTNFDDAGTYTCDVSNGVGNAQSFSIILNVNSVPYFTKEPEIATAA 351

Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
                 F C A G PEP + W   G      P           V D  T+  IN   K D
Sbjct: 352 EDEEVVFECRAAGVPEPKISWIHNGK-----PIEQSTPNPRRTVTDN-TIRIIN-LVKGD 404

Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
           + N   C+A N  G  +    L V ++    PP I+  P+  +          C    +P
Sbjct: 405 TGN-YGCNATNSLGYVYKDVYLNVQAE----PPTISEAPAAVSTVDGRNVTIKCRVNGSP 459

Query: 426 EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
           +P++ W       +   R NV  +G L ++D+  SD+G YTC A ++ G+    G+L+V
Sbjct: 460 KPLVKW-LRASNWLTGGRYNVQANGDLEIQDVTFSDAGKYTCYAQNKFGEIQADGSLVV 517



 Score =  102 bits (244), Expect = 7e-20
 Identities = 78/288 (27%), Positives = 117/288 (40%), Gaps = 15/288 (5%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT--HRSILPAGGLFFL 69
           PY  ++P   T A  +     CRA G P P I W   G  +   T   R  +    +  +
Sbjct: 339 PYFTKEPEIATAAEDEEVVFECRAAGVPEPKISWIHNGKPIEQSTPNPRRTVTDNTIRII 398

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
               G    D G Y C ATNS G    ++  L+V          P +  +  G  V ++C
Sbjct: 399 NLVKG----DTGNYGCNATNSLGYV-YKDVYLNVQAEPPTISEAPAAVSTVDGRNVTIKC 453

Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
               GSP+P V W +    L      R ++   G+L IQD   +DAG+Y C A+N  G  
Sbjct: 454 -RVNGSPKPLVKWLRASNWLT---GGRYNVQANGDLEIQDVTFSDAGKYTCYAQNKFGEI 509

Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV---LWRRSAGGGNMPL 246
           + A  +L +     +   P++     G S TF+C    D   ++    W+          
Sbjct: 510 Q-ADGSLVVKEHTRITQEPQNYEVAAGQSATFRCNEAHDDTLEIEIDWWKDGQSIDFEAQ 568

Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
            R    +D SL +   +  D GEY+C A   +   +A   L V D P+
Sbjct: 569 PRFVKTNDNSLTIAKTMELDSGEYTCVARTRLDEATARANLIVQDVPN 616



 Score = 94.3 bits (224), Expect = 2e-17
 Identities = 115/424 (27%), Positives = 171/424 (40%), Gaps = 47/424 (11%)

Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDG-DSRMHLVDG-GNLVI 167
           F++  ++K+S   +  ++EC    G PEP   W KNG+   +   D+RM    G G LVI
Sbjct: 42  FKVAQQNKES--DNPFIIEC-EADGQPEPEYSWIKNGKKFDWQAYDNRMLRQPGRGTLVI 98

Query: 168 QDARQTDAGRYQCIARNAAGTRES-AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV- 225
              +  D G YQC A N  GT  S ++   K  +  +     + + A  G     +C   
Sbjct: 99  TIPKDEDRGHYQCFASNEFGTATSNSVYVRKAELNAFKDEAAKTLEAVEGEPFMLKCAAP 158

Query: 226 GGDPLPDVLW--RRSAGGGNMPLGRVKV-LD-DGSLRLDNVILADEGE---YSCEA---- 274
            G P P V W  + S  G    +   ++ LD +G+L   NV   D      Y+C A    
Sbjct: 159 DGFPSPTVNWMIQESIDGSIKSINNSRMTLDPEGNLWFSNVTREDASSDFYYACSATSVF 218

Query: 275 --ENSVG--------AVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTM 324
             E  +G         +  S     + P    +S        G      C   G P P  
Sbjct: 219 RSEYKIGNKVLLDVKQMGVSASQNKHPPVRQYVSRRQSLALRGKRMELFCIYGGTPLPQT 278

Query: 325 FWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR 384
            WS +G R      +++  Y  +        L I  T+ +D+  T  C   N  G++   
Sbjct: 279 VWSKDGQRIQWSDRITQGHYGKS--------LVIRQTNFDDA-GTYTCDVSNGVGNA--- 326

Query: 385 GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ---N 441
              ++  + +   P  T  P   T       VF C A   PEP I+W   G+ + Q   N
Sbjct: 327 QSFSIILNVN-SVPYFTKEPEIATAAEDEEVVFECRAAGVPEPKISWIHNGKPIEQSTPN 385

Query: 442 HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVS 501
            RR VT D T+ + +L K D+G Y C A++  G YV+    L      P I    AA VS
Sbjct: 386 PRRTVT-DNTIRIINLVKGDTGNYGCNATNSLG-YVYKDVYLNVQAEPPTISEAPAA-VS 442

Query: 502 SLPG 505
           ++ G
Sbjct: 443 TVDG 446



 Score = 76.6 bits (180), Expect = 4e-12
 Identities = 49/177 (27%), Positives = 80/177 (45%), Gaps = 12/177 (6%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
           E P I E P  V+    +  T+ CR  GSP P ++W +    +    + ++   G L   
Sbjct: 430 EPPTISEAPAAVSTVDGRNVTIKCRVNGSPKPLVKWLRASNWLTGGRY-NVQANGDLEIQ 488

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL--EPESKQSAQGDTVVL 127
             T     SDAG Y C A N +G  ++  +     V++E  R+  EP++ + A G +   
Sbjct: 489 DVT----FSDAGKYTCYAQNKFGEIQADGS----LVVKEHTRITQEPQNYEVAAGQSATF 540

Query: 128 ECLPPRGSP-EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
            C        E  + W K+GQ++ F+   R    +  +L I    + D+G Y C+AR
Sbjct: 541 RCNEAHDDTLEIEIDWWKDGQSIDFEAQPRFVKTNDNSLTIAKTMELDSGEYTCVAR 597


>UniRef50_Q0E9K8 Cluster: CG17800-PAN; n=84; Endopterygota|Rep:
            CG17800-PAN - Drosophila melanogaster (Fruit fly)
          Length = 2037

 Score =  153 bits (371), Expect = 3e-35
 Identities = 203/849 (23%), Positives = 332/849 (39%), Gaps = 98/849 (11%)

Query: 12   PYIIEQPLDVTVARHQPAT-LNCRAGGSPSPAIRWYKGGVLVVSDTHRSI---LPAGGLF 67
            P +I Q          P+  L C AGG+P+P I W   G  + ++    +   +   G  
Sbjct: 429  PPVIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQYVTVNGDV 488

Query: 68   FLRATHGRVHS-DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
                    VH+ D G+Y C A +  G A   +A L+V  L   +  + E K    G+T++
Sbjct: 489  VSYLNITSVHANDGGLYKCIAKSKVGVAE-HSAKLNVYGL--PYIRQMEKKAIVAGETLI 545

Query: 127  LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA-RQTDAGRYQCIARNA 185
            + C P  G P  ++ W+++ + L  +   +  +   G L+I++  R +D   Y C+A+N 
Sbjct: 546  VTC-PVAGYPIDSIVWERDNRALPIN--RKQKVFPNGTLIIENVERNSDQATYTCVAKNQ 602

Query: 186  AGTRESAIATLKIHIKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGG 242
             G        +++ + P ++  P D   +T      V+  C V     P  L+  +A   
Sbjct: 603  EGYSARGSLEVQVMVPPQVV--PFDFGEETINMNDMVSATCTVNKGDTPLELYWTTAPDP 660

Query: 243  NMPLGRVKVLDD----------GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
               +GR+   D             L +++V       Y+C A N+ G +  +  L V  P
Sbjct: 661  TTGVGRLMSNDGILITKTTQRISMLSIESVHARHRANYTCVARNAAGVIYHTAELRVNVP 720

Query: 293  PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
            P   L P       G+ A+  C A G P+P + W      T   PG  +D   +  +   
Sbjct: 721  PRWILEPTDKAFAQGSDAKVECKADGFPKPQVTWKKAVGDT---PGEYKDLKKSDNIRVE 777

Query: 353  VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
               L +++  K  +    +C A+N  GS    G   V     + PP  T    NQT    
Sbjct: 778  EGTLHVDNIQKT-NEGYYLCEAINGIGS----GLSAVIMISVQAPPEFTEKLRNQTARRG 832

Query: 413  SMAVFPCTAICTPEPIIAWYFEGEALIQNH------RRNVTNDG---TLVLKDLDKSDSG 463
              AV  C A       I W      L   +      R  + + G   +L +K  ++SDS 
Sbjct: 833  EPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGVMSSLSIKRTERSDSA 892

Query: 464  TYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLS 523
             +TCVA++  G          D+ IN          V  +P  P      + +  SV LS
Sbjct: 893  LFTCVATNAFGS--------DDASIN--------MIVQEVPEMPYALKVLDKSGRSVQLS 936

Query: 524  WSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITY 583
            W+Q    G+S +  Y +E F R   S +   R     V++    H T   V+ L P  TY
Sbjct: 937  WAQPYD-GNSPLDRYIIE-FKRSRASWSEIDR-----VIVPG--HTTEAQVQKLSPATTY 987

Query: 584  MFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATP 643
               +  EN+ G S  S     +T  +           + S + +N          I+  P
Sbjct: 988  NIRIVAENAIGTSQSSEAVTIITAEE-----------APSGKPQN----------IKVEP 1026

Query: 644  IDSKTIKLMWEILNFYYLEGLFI-YF--RPLDNITIEYEMKT---ILHSNDVSGFEITSL 697
            ++  T+++ W+        G  + Y+    L N    Y  +T   I         E+ +L
Sbjct: 1027 VNQTTMRVTWKPPPRTEWNGEILGYYVGYKLSNTNSSYVFETINFITEEGKEHNLELQNL 1086

Query: 698  RKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPEL 757
            R YT+Y   +  F K   G  S      T +  P  PP +     L + T+ + W  P L
Sbjct: 1087 RVYTQYSVVIQAFNKIGAGPLSEEEKQFTAEGTPSQPPSDTACTTLTSQTIRVGWVSPPL 1146

Query: 758  QLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817
            +  NG+I  Y VV    D   +++      T    T  ++  L    +Y++Q+ A T  G
Sbjct: 1147 ESANGVIKTYKVVYAPSDEWYDETKRHYKKTASSDT--VLHGLKKYTNYTMQVLATTAGG 1204

Query: 818  LGPFSQKVY 826
             G  S  ++
Sbjct: 1205 DGVRSVPIH 1213



 Score =  124 bits (299), Expect = 1e-26
 Identities = 148/585 (25%), Positives = 235/585 (40%), Gaps = 68/585 (11%)

Query: 10  EAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTH--RSILPAGGL 66
           + P  +++P + +  +    A + C+A G+P P I W +     V D    R I   G L
Sbjct: 37  KGPVFLKEPTNRIDFSNSTGAEIECKASGNPMPEIIWIRSDGTAVGDVPGLRQISSDGKL 96

Query: 67  FF--LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV-AVLREEFRLEPESKQSAQGD 123
            F   RA   R    A VY C A N +G+  SR+  +HV AV+ + +  E  ++   +G+
Sbjct: 97  VFPPFRAEDYRQEVHAQVYACLARNQFGSIISRD--VHVRAVVNQFYEAEIMTEYVIRGN 154

Query: 124 TVVLECLPPRGSPE---PNVYWKKNGQTLLFDG--DSRMHLVDGGNLVIQDARQTDAGR- 177
             VL+C  P    +      +    G  L F    D +  ++  G L I++    D  + 
Sbjct: 155 AAVLKCSIPSFVADFVRVESWIDDEGNVLSFSDNYDGKYLVLPSGELHIREVGPEDGYKS 214

Query: 178 YQCIARN--AAGTRESAIATLKIHIKPYLITGPE---------DVVAQTGSSVTFQCRVG 226
           YQC  ++     TR SA     +  +P     P          D + Q  +   F C   
Sbjct: 215 YQCRTKHRLTGETRLSATKGRLVITEPVGSVAPRVNKKDGFSHDSIRQDRTIAIF-CPAQ 273

Query: 227 GDPLPDVLWRRSAGGGNMPLG-----RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281
             P+P   W +   G           RVK +  G+L + + ++ D G+Y C   NSVG  
Sbjct: 274 AYPVPFYRWYKFIEGTTRKQAVVLNDRVKQVS-GTLIIKDAVVEDSGKYLCVVNNSVGGE 332

Query: 282 SASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341
           S    LTV  P S  + P +  V+ G  A FTC  TG P  T+ W  +G           
Sbjct: 333 SVETVLTVTAPLSAKIDPPTQTVDFGRPAVFTCQYTGNPIKTVSWMKDGK---------- 382

Query: 342 DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401
                 A+     VL I    K D +    C   N   S+    +L +    D  PP+I 
Sbjct: 383 ------AIGHSEPVLRIESVKKED-KGMYQCFVRNDQESAEASAELKLGGRFD--PPVIR 433

Query: 402 NGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR----RNVTNDGTLV---- 453
                +T+         C A   P P I+W  +G+ +  N R    + VT +G +V    
Sbjct: 434 QAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQYVTVNGDVVSYLN 493

Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITH 513
           +  +  +D G Y C+A S+ G    S  L V       + + R  +  ++    T  +T 
Sbjct: 494 ITSVHANDGGLYKCIAKSKVGVAEHSAKLNV-----YGLPYIRQMEKKAIVAGETLIVTC 548

Query: 514 NVTDTSV-TLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNS 557
            V    + ++ W ++N+   +  +  + +VF   TL   N  RNS
Sbjct: 549 PVAGYPIDSIVWERDNR---ALPINRKQKVFPNGTLIIENVERNS 590



 Score =  111 bits (266), Expect = 1e-22
 Identities = 108/414 (26%), Positives = 169/414 (40%), Gaps = 29/414 (7%)

Query: 121 QGDTVVLECLPPRGSPEPNVYWKK--NGQTL--LFDGDSRMHLVDGGNLVIQDARQTDAG 176
           Q  T+ + C P +  P P   W K   G T       + R+  V G  L+I+DA   D+G
Sbjct: 262 QDRTIAIFC-PAQAYPVPFYRWYKFIEGTTRKQAVVLNDRVKQVSG-TLIIKDAVVEDSG 319

Query: 177 RYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
           +Y C+  N+ G  ES    L +         P       G    F C+  G+P+  V W 
Sbjct: 320 KYLCVVNNSVGG-ESVETVLTVTAPLSAKIDPPTQTVDFGRPAVFTCQYTGNPIKTVSWM 378

Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDPP 293
           +         G+     +  LR+++V   D+G Y C   N   +  AS  L +   +DPP
Sbjct: 379 KD--------GKAIGHSEPVLRIESVKKEDKGMYQCFVRNDQESAEASAELKLGGRFDPP 430

Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
            I  +     +E G      C A G P P + W ++G +          +Y  T   D V
Sbjct: 431 VIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQY-VTVNGDVV 489

Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413
           + L I     ND      C A +  G +    KL V        P I        +  ++
Sbjct: 490 SYLNITSVHANDG-GLYKCIAKSKVGVAEHSAKLNVYG-----LPYIRQMEKKAIVAGET 543

Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDK-SDSGTYTCVASSR 472
           + V  C     P   I W  +  AL  N ++ V  +GTL+++++++ SD  TYTCVA ++
Sbjct: 544 LIV-TCPVAGYPIDSIVWERDNRALPINRKQKVFPNGTLIIENVERNSDQATYTCVAKNQ 602

Query: 473 HGKYVWSGALLVDSPINPN-IHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWS 525
            G Y   G+L V   + P  + F    +  ++    +   T N  DT + L W+
Sbjct: 603 EG-YSARGSLEVQVMVPPQVVPFDFGEETINMNDMVSATCTVNKGDTPLELYWT 655



 Score = 60.1 bits (139), Expect = 4e-07
 Identities = 32/104 (30%), Positives = 50/104 (48%)

Query: 384  RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR 443
            + K  V    D+ P  I +     T   K  A  PC A+  P+P I W  +G     N R
Sbjct: 1305 QSKSIVAMPSDQVPAKIASFDDTFTATFKEDAKMPCLAVGAPQPEITWKIKGVEFSANDR 1364

Query: 444  RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
              V  DG+L++K +++ D+G Y+C A +   K   +  L+V +P
Sbjct: 1365 MRVLPDGSLLIKSVNRQDAGDYSCHAENSIAKDSITHKLIVLAP 1408



 Score = 52.4 bits (120), Expect = 7e-05
 Identities = 34/108 (31%), Positives = 48/108 (44%), Gaps = 2/108 (1%)

Query: 187  GTRESAIATLKIHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
            G +  +I  +     P  I   +D    T        C   G P P++ W+   G     
Sbjct: 1303 GQQSKSIVAMPSDQVPAKIASFDDTFTATFKEDAKMPCLAVGAPQPEITWKIK-GVEFSA 1361

Query: 246  LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
              R++VL DGSL + +V   D G+YSC AENS+   S +  L V  PP
Sbjct: 1362 NDRMRVLPDGSLLIKSVNRQDAGDYSCHAENSIAKDSITHKLIVLAPP 1409



 Score = 49.6 bits (113), Expect = 5e-04
 Identities = 43/186 (23%), Positives = 75/186 (40%), Gaps = 8/186 (4%)

Query: 642  TPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFE--ITSLRK 699
            T + S+TI++ W         G+   ++ +   + E+  +T  H    +  +  +  L+K
Sbjct: 1130 TTLTSQTIRVGWVSPPLESANGVIKTYKVVYAPSDEWYDETKRHYKKTASSDTVLHGLKK 1189

Query: 700  YTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQL 759
            YT Y   ++      +G  S     QT  DVP+  P +++  ++    + + W PP    
Sbjct: 1190 YTNYTMQVLATTAGGDGVRSVPIHCQTEPDVPEA-PTDVKALVMGNAAILVSWRPP--AQ 1246

Query: 760  QNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819
             NGIIT Y V   +      ++        H   S   T L     Y   + A T IG G
Sbjct: 1247 PNGIITQYTV---YSKAEGAETETKTQKVPHYQMSFEATELEKNKPYEFWVTASTTIGEG 1303

Query: 820  PFSQKV 825
              S+ +
Sbjct: 1304 QQSKSI 1309



 Score = 46.8 bits (106), Expect = 0.004
 Identities = 45/183 (24%), Positives = 77/183 (42%), Gaps = 12/183 (6%)

Query: 134  GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
            G+P+P + WK  G  + F  + RM ++  G+L+I+   + DAG Y C A N+   ++S  
Sbjct: 1344 GAPQPEITWKIKG--VEFSANDRMRVLPDGSLLIKSVNRQDAGDYSCHAENSI-AKDSIT 1400

Query: 194  ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV-GGD--PLPDVLWRRSAGGGNMPLGRVK 250
              L +   P   +    + A T  ++T + +   GD  PL           G      V 
Sbjct: 1401 HKLIVLAPPQ--SPHVTLSATTTDALTVKLKPHEGDTAPLHGYTLHYKPEFGEWETSEVS 1458

Query: 251  VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYL---TVYDPPSINLSPNSVNVESG 307
            V D     ++ ++     +      N++GA  AS  L   T    P +   P  + V S 
Sbjct: 1459 V-DSQKHNIEGLLCGSRYQVYATGFNNIGAGEASDILNTRTKGQKPKLPEKPRFIEVSSN 1517

Query: 308  NVA 310
            +V+
Sbjct: 1518 SVS 1520



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 23/69 (33%), Positives = 29/69 (42%), Gaps = 4/69 (5%)

Query: 22   TVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAG 81
            T    + A + C A G+P P I W   GV   ++    +LP G L            DAG
Sbjct: 1329 TATFKEDAKMPCLAVGAPQPEITWKIKGVEFSANDRMRVLPDGSLLIKSVN----RQDAG 1384

Query: 82   VYWCEATNS 90
             Y C A NS
Sbjct: 1385 DYSCHAENS 1393


>UniRef50_A5X6X5 Cluster: Titin a; n=10; Euteleostomi|Rep: Titin a -
            Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 32757

 Score =  152 bits (369), Expect = 5e-35
 Identities = 137/491 (27%), Positives = 201/491 (40%), Gaps = 24/491 (4%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
            +T  E   I EQ   V+V    PATL CR  G+     +W K G  + S     I  +  
Sbjct: 5637 LTVKEPANITEQAKSVSVTVRDPATLECRYSGTKVLKAKWLKDGNELTSGRKYKIQSSDT 5696

Query: 66   LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNA-TLHVAVLREEFRLEPESKQSAQGDT 124
               L+       SDAG Y  E +N  G +      T+   +++  F  + +  +S +G  
Sbjct: 5697 SSILKILSAE-KSDAGEYTFEVSNDAGRSSCEAVVTVLDQIIKPSFTRKLKETESIKGSF 5755

Query: 125  VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSR-MHLVDGGNLVIQDARQTDAGRYQCIAR 183
              LECL   GS   NV W K  + +  D   + +   +  +L I     +D+G Y CIA+
Sbjct: 5756 TQLECLVS-GSLPINVTWFKENKEIEADEKHKCIFFENAASLEISRLDSSDSGNYTCIAK 5814

Query: 184  NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG--G 241
            N AG+ + +  TLK+   P +I  PE      GS V F   + G P   + W +      
Sbjct: 5815 NQAGSDQCS-GTLKVKEPPSIIEKPESQDVIPGSKVQFNVLLSGTPPLTINWFKDTKEVS 5873

Query: 242  GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
              +     K     S+ L     +D G+Y CE  N VG+ S    L V +PP     P  
Sbjct: 5874 SGIDCSVQKNDTSSSIELFFAKPSDSGQYVCEVSNDVGSDSCQATLFVKEPPKFTRKPEK 5933

Query: 302  VN-VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
            +  V+   +  F C  TG PE   +W  +GN   I P    DKY  T V D +  L I  
Sbjct: 5934 ITVVKPSQLVVFECQITGTPEIDTYWFKDGND--ISPS---DKYKMTFV-DSLARLEIIS 5987

Query: 361  TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
            +D  DS     C A N AGS      L V     + PP++    S   +   S A F C 
Sbjct: 5988 SDIKDS-GVYYCEARNEAGSESCSMDLRV-----KEPPVLVKPLSPLEVVNGSNAYFECL 6041

Query: 421  AICTPEPIIAWYFEGEALIQNHRRNV--TNDG--TLVLKDLDKSDSGTYTCVASSRHGKY 476
               T    + W  + + +  + +  +   ND   TL ++  D  D G Y C+ ++  G  
Sbjct: 6042 VKGTAPFEVTWEKDSKDIKSSLKHVILQKNDSIITLDVQKCDALDVGEYQCIVANEVGSC 6101

Query: 477  VWSGALLVDSP 487
                 L +  P
Sbjct: 6102 SSQSTLSIKEP 6112



 Score =  139 bits (336), Expect = 5e-31
 Identities = 122/487 (25%), Positives = 203/487 (41%), Gaps = 30/487 (6%)

Query: 10   EAPYIIEQPLDVTVAR-HQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
            E P    +P  +TV +  Q     C+  G+P     W+K G  +       +     L  
Sbjct: 5923 EPPKFTRKPEKITVVKPSQLVVFECQITGTPEIDTYWFKDGNDISPSDKYKMTFVDSLAR 5982

Query: 69   LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK-QSAQGDTVVL 127
            L      +  D+GVY+CEA N  G   S + ++ + V      ++P S  +   G     
Sbjct: 5983 LEIISSDI-KDSGVYYCEARNEAG---SESCSMDLRVKEPPVLVKPLSPLEVVNGSNAYF 6038

Query: 128  ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV--DGGNLVIQDARQTDA---GRYQCIA 182
            ECL  +G+    V W+K+ + +     S  H++     +++  D ++ DA   G YQCI 
Sbjct: 6039 ECLV-KGTAPFEVTWEKDSKDIK---SSLKHVILQKNDSIITLDVQKCDALDVGEYQCIV 6094

Query: 183  RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG- 241
             N  G+  S  +TL I   P  +   E+VV   G  V F+C V G P   + W++     
Sbjct: 6095 ANEVGSCSSQ-STLSIKEPPSFVERIENVVTVLGKMVEFKCVVRGSPPLSIQWQKDESWI 6153

Query: 242  -GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
              +  + R    +  +L +        G+Y+C+A N  G       L V +PP I   P 
Sbjct: 6154 LEDPSIQRTFENNVATLTIPVCESIHSGKYTCQAMNEAGQEKCFSTLVVQEPPQIIEKPE 6213

Query: 301  SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
             +NV +G+   F C  +G PE  + WS +G   I        + H+ +  + V+ L +  
Sbjct: 6214 VINVTAGDPVSFECKVSGTPELKVKWSKDGKEVI------PSRQHSLSYINNVSQLKLQS 6267

Query: 361  TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
                D + T V    N+  +   +  L V  +   PP  I      + +  K++ +  C 
Sbjct: 6268 VQLED-KGTYVFEVSNHISACQCKVTLNVL-EQIIPPSFIKPLMEMEEIIGKNVQI-GCK 6324

Query: 421  AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKD---LDKSDSGTYTCVASSRHGKYV 477
               +    + W  +G  L    +  +  D   V  D   L+K+D+GTYTC  +++ G   
Sbjct: 6325 ISGSLPITVEWEKDGTKLSGRTKHKILQDENSVSLDIECLEKADTGTYTCKLANKAGSCE 6384

Query: 478  WSGALLV 484
             SG L V
Sbjct: 6385 CSGTLRV 6391



 Score =  138 bits (333), Expect = 1e-30
 Identities = 129/531 (24%), Positives = 218/531 (41%), Gaps = 26/531 (4%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            E P  +  P  V        T      GS    ++W++G   +VS     I   G    L
Sbjct: 6935 EPPSFVTTPQPVEALPGTTVTFTATVQGSTPMKLKWFRGSKEIVSGRSCEIALRGDTAIL 6994

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDTVVLE 128
               H    S AG Y C+  N  G     N  +++ V      ++     S + G +++LE
Sbjct: 6995 EL-HNIDKSHAGEYTCQIINDAG---KENCPVNLFVKEAAHFVKKLKNLSVEMGKSLILE 7050

Query: 129  CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAG 187
            C    GSP+  V W K+GQ +       +   +   ++   ++ +  AG+Y C   N AG
Sbjct: 7051 CTYA-GSPKILVKWHKDGQEIYSSYKYNITTTESSCILECLNSDKEAAGKYTCEVSNDAG 7109

Query: 188  TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPL 246
              +   A + I   P+ I   E +    G +V  +C++GG P   + W ++ G   + P 
Sbjct: 7110 -HDICEAAVSILEPPFFIESLEPMEVTAGDAVCLKCQIGGTPEIKISWFKADGKVRSSPT 7168

Query: 247  GRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLSPNSV 302
             +++       L+L  V  +D GEY+C+AENS+G+ ++S +LTV D   PPS      S+
Sbjct: 7169 CKMEFFKGIACLKLAKVAKSDIGEYTCKAENSIGSATSSCHLTVQDVKTPPSFPKKITSI 7228

Query: 303  NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
                G   +F C   G     + W  +G        +  D  +  +  D   VL I   +
Sbjct: 7229 MQIEGQPVQFECRVAGSSPMEVSWLKDGE------ALRSDSEYTMSFDDNSAVLNIAKGE 7282

Query: 363  KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
               S     C A N  GS+  R KLT+   + R PP+         + +       C   
Sbjct: 7283 MRHS-GEYTCVATNSVGSASCRAKLTL--QEPRYPPVFDKKLVPVDVSVGDTVELECHMT 7339

Query: 423  CTPEPIIAWYFEGEALIQ--NHRRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479
             +    + W  + + +    N++ + V N   L +   DK+DSG Y+C AS+  GK   S
Sbjct: 7340 GSMPIKVTWSKDHKDIRTGGNYKISCVENTPHLTILKADKADSGRYSCHASNDVGKDSCS 7399

Query: 480  GALLV-DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
              + V +  I P+     +  +  + G   K          +T++W ++ +
Sbjct: 7400 TEVSVKERKIPPSFTKKPSTTIEDIEGKVVKIEGRVAGSQPLTVNWYKDGR 7450



 Score =  122 bits (293), Expect = 8e-26
 Identities = 134/530 (25%), Positives = 213/530 (40%), Gaps = 29/530 (5%)

Query: 10   EAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
            E P  +++ P    V   +P  L C+  G+    I WYK    ++SD     +       
Sbjct: 6465 EPPEFVQKLPAAKVVKMGEPLQLECKVTGTAPLRISWYKNDA-ILSDGGNLRMTFDNSVA 6523

Query: 69   LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
            +         D GVY CEA N  GT +S +  L +      ++L P   +  +G    L 
Sbjct: 6524 VLEISTSSFDDNGVYTCEAQNDAGT-KSCSTALTIKEPPSFYKL-PTPVEGLKGKDASLN 6581

Query: 129  CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAA 186
            C   +GS    + W K+ + L  +      + +G    L I     +DAG Y+C A N  
Sbjct: 6582 C-ELKGSAPFEITWFKDKKQLK-ESRKYKFVSEGCSATLHILGLEASDAGEYECKATNNV 6639

Query: 187  GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
            G+ +    ++K+   P  +    +  A +G  V     V G     V W +         
Sbjct: 6640 GS-DLCQGSVKLREPPAFVKKLSNTTAISGEEVVLLTTVKGSQPMTVSWVQDKDHILRDG 6698

Query: 247  GRVKVLDDGSLRLDNVILADE---GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
               K+  + +     V  AD    G+Y+C+ +N  G    +  LTV +P +I    +S++
Sbjct: 6699 ENRKITFENNEVTLKVFKADSTTAGKYTCQLKNDAGVAECTANLTVLEPAAIVDKTDSIS 6758

Query: 304  VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
            V +G  A   CT +G PE    W  +G        +S  K +       ++ L +  T++
Sbjct: 6759 VTAGEAAALECTVSGTPELKPKWFKDGVE------LSSGKKYKITFSKMISSLKLLSTER 6812

Query: 364  NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
            +D+      S  N  GS     +LTV  D   PP         Q++  KSM +  C A  
Sbjct: 6813 SDT-GEYTFSIKNEVGSDSCAMQLTVL-DKIVPPLFSRKLKDTQSIVGKSMEL-DCKASG 6869

Query: 424  TPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
            +    I+W+     ++      +T   N  TL +  L  SDSGTY C A +  G    S 
Sbjct: 6870 SAPLTISWFHNEVEIMSGPNYEITFTENTCTLKVPTLKLSDSGTYKCKAVNSAGAAETSA 6929

Query: 481  ALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVT-DTSVTLSWSQNNK 529
            +L+V  P  P+        V +LPG  T   T  V   T + L W + +K
Sbjct: 6930 SLVVKEP--PSF-VTTPQPVEALPG-TTVTFTATVQGSTPMKLKWFRGSK 6975



 Score =  120 bits (289), Expect = 2e-25
 Identities = 137/535 (25%), Positives = 217/535 (40%), Gaps = 35/535 (6%)

Query: 13   YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRAT 72
            ++++  L   V     ATL C+  GSP  +IRWYK    + SD    +     +  LR +
Sbjct: 5365 FVMKLDLTKLVLNGSLATLECKVAGSPEISIRWYKNETEIGSDDKYQMAFTDSVATLRIS 5424

Query: 73   HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP 132
               V  D+G Y C+A++  G+ R   + L       EF    ESK+  +G  VVLE    
Sbjct: 5425 SCCVE-DSGDYICQASSDAGSDRC--SCLVTVKEPPEFVKPFESKEIVKGTDVVLEGTVS 5481

Query: 133  RGSPEPNVYWKKNGQTLLFDGDSRMHLV----DGGNLVIQDARQTDAGRYQCIARNAAG- 187
              +P     +K + Q      + R H++    D   L I      DAG+YQC   N  G 
Sbjct: 5482 GSAPFEISCFKDSKQIR----NDRRHIISLTKDVAALQILKFEPGDAGKYQCTVGNEVGQ 5537

Query: 188  TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
            T    + T+K    P  +   ++        V+ QC + G     + W +          
Sbjct: 5538 TSCDFLVTMKE--PPSFVQKMDNTNVLLAKDVSLQCVLKGSMPMTISWMKD-DHEIKESE 5594

Query: 248  RVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
             V++  +     + + +V L   G+Y+C A+N  G+   +  LTV +P +I     SV+V
Sbjct: 5595 HVQISFENQTAVIYISSVQLKHGGKYTCHAQNEAGSQKCTAVLTVKEPANITEQAKSVSV 5654

Query: 305  ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
               + A   C  +G       W  +GN        S  KY   +  D  ++L I   +K+
Sbjct: 5655 TVRDPATLECRYSGTKVLKAKWLKDGNEL-----TSGRKYKIQS-SDTSSILKILSAEKS 5708

Query: 365  DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK-SMAVFPCTAIC 423
            D+         N AG S     +TV   D    P  T     +T  IK S     C    
Sbjct: 5709 DA-GEYTFEVSNDAGRSSCEAVVTVL--DQIIKPSFTR-KLKETESIKGSFTQLECLVSG 5764

Query: 424  TPEPIIAWYFEGEALIQNHRRN---VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
            +    + W+ E + +  + +       N  +L +  LD SDSG YTC+A ++ G    SG
Sbjct: 5765 SLPINVTWFKENKEIEADEKHKCIFFENAASLEISRLDSSDSGNYTCIAKNQAGSDQCSG 5824

Query: 481  ALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSI 535
             L V  P  P+I   +      +PG   +          +T++W ++ K  SS I
Sbjct: 5825 TLKVKEP--PSI-IEKPESQDVIPGSKVQFNVLLSGTPPLTINWFKDTKEVSSGI 5876



 Score =  119 bits (287), Expect = 4e-25
 Identities = 124/482 (25%), Positives = 193/482 (40%), Gaps = 31/482 (6%)

Query: 17   QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV 76
            Q L+V V     A   C    +P    +W+K G  +       I+       L      V
Sbjct: 4622 QNLEVNVG--SSAKFECEIEEAPGVTFKWFKSGTELRHSEKCRIISRHHTSSLEIFSPAV 4679

Query: 77   HSDAGVYWCEATNSYGTARSRNATLHVAVL-REEFRLEPESKQSAQGDTVVLECLPPRGS 135
             +D+G Y C+A+N +G + S +A L V  L   EF  +P+S     G     +C+   GS
Sbjct: 4680 -ADSGEYTCKASNRHG-SDSCSAKLTVTELFPPEFVSKPDSMTLFVGKQAKFQCV-ISGS 4736

Query: 136  PEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAI 193
               NV W K+   +  D D      D     L I + + +D G Y C A N+ GT  +  
Sbjct: 4737 EPMNVVWHKDNIAISLD-DHYKESSDKNRYFLEILNLQHSDQGTYLCKASNSVGT-ATCC 4794

Query: 194  ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD 253
              L++  KP  +   E      G+ +  +C+V  D    ++W R     +  +      +
Sbjct: 4795 TELRVVDKPSFVKSFESTTVAVGNPLRLECQVDEDTGVSIIWMRDGKKLHTTMDCKLAFE 4854

Query: 254  D--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNVESGNV 309
            +    L +    L D G Y+C A N  G+ S S  +TV +PP     L P  +  + G  
Sbjct: 4855 EKIACLDIQKSKLKDTGTYTCTAANEAGSSSCSSSVTVQEPPVFVKRLEP-KILWKQGMS 4913

Query: 310  ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
            +R +CT  G PE  + W +        P  S +K+  T   +  T L I D  ++DS N 
Sbjct: 4914 SRLSCTVKGSPELHVTWFLNDK-----PLNSSEKHKITFKTNQAT-LEIIDLSESDSGN- 4966

Query: 370  IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
              C  +N AG      ++TV     + PP          +     A   C    T    I
Sbjct: 4967 YTCEVMNEAGCESCSSQVTV-----KEPPAFKKELRLVEVVKGCTAHLECEMTGTAPFEI 5021

Query: 430  AWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSG-ALLVD 485
             W+ +   +  + + N+ +  T   L +K  + +D G Y C  S+  GK      A L D
Sbjct: 5022 TWFKDKNPVSSDTKYNIVSKETAAYLEIKTFESADVGDYQCCISNDVGKITTKAVAKLKD 5081

Query: 486  SP 487
             P
Sbjct: 5082 PP 5083



 Score =  119 bits (287), Expect = 4e-25
 Identities = 128/483 (26%), Positives = 186/483 (38%), Gaps = 37/483 (7%)

Query: 27   QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
            QP    CR  GS    + W K G  + SD+  ++        L    G +   +G Y C 
Sbjct: 7234 QPVQFECRVAGSSPMEVSWLKDGEALRSDSEYTMSFDDNSAVLNIAKGEMRH-SGEYTCV 7292

Query: 87   ATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
            ATNS G+A  R   TL        F  +      + GDTV LEC    GS    V W K+
Sbjct: 7293 ATNSVGSASCRAKLTLQEPRYPPVFDKKLVPVDVSVGDTVELEC-HMTGSMPIKVTWSKD 7351

Query: 146  GQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAG--TRESAIATLKIHIKP 202
             + +   G+ ++  V+   +L I  A + D+GRY C A N  G  +  + ++  +  I P
Sbjct: 7352 HKDIRTGGNYKISCVENTPHLTILKADKADSGRYSCHASNDVGKDSCSTEVSVKERKIPP 7411

Query: 203  YLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLR--- 258
                 P   +    G  V  + RV G     V W +  G          V    SL    
Sbjct: 7412 SFTKKPSTTIEDIEGKVVKIEGRVAGSQPLTVNWYKD-GREIFTSDFYDVTFKSSLAVLC 7470

Query: 259  LDNVILADEGEYSCEAENSVGAVS--ASGYLTVYD-PPSINLSPNSVNVESGNVARFTCT 315
            +    L+D G Y C+A N  G  S   S ++T    PPS +L    V V  G     +C 
Sbjct: 7471 IKKSQLSDSGTYVCKATNEAGTASFEVSVHITAQKVPPSFDLPLKPVTVNEGETLTLSCH 7530

Query: 316  ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
              G P   + W  +         +S          DG   L +    K DS + + C A 
Sbjct: 7531 VRGSPPLKIQWMKDRRE------LSSSANTKITFVDGTATLEMTRVSKTDSGDYL-CKAT 7583

Query: 376  NYAGSSFVRGKLTVTSDDDRPPPIITNG--------PSNQTLPIKSMAVFPCTAICTPEP 427
            N AG+    G          PP  +           P +  +  K  A F       P P
Sbjct: 7584 NEAGNK--PGAPAPAQAAPSPPQEVKKFDNLFFIEVPKSVHIVEKGTATFIAKVGGDPIP 7641

Query: 428  IIAWYFEGEALIQNHRRNVT-----NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482
             + W  +G+     H   ++      +  + +K++ KSDSG Y CVAS++HG+   S  L
Sbjct: 7642 NVKW-MKGKWRQMTHGGRISIEQKGQEAKMEIKEVTKSDSGQYRCVASNKHGEIECSTDL 7700

Query: 483  LVD 485
             VD
Sbjct: 7701 NVD 7703



 Score =  119 bits (286), Expect = 6e-25
 Identities = 122/493 (24%), Positives = 198/493 (40%), Gaps = 31/493 (6%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
            VT    P  + +P  +T+   + A   C   GS    + W+K  + +  D H        
Sbjct: 4704 VTELFPPEFVSKPDSMTLFVGKQAKFQCVISGSEPMNVVWHKDNIAISLDDHYKESSDKN 4763

Query: 66   LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
             +FL   + + HSD G Y C+A+NS GTA     T    V +  F    ES   A G+ +
Sbjct: 4764 RYFLEILNLQ-HSDQGTYLCKASNSVGTATC--CTELRVVDKPSFVKSFESTTVAVGNPL 4820

Query: 126  VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARN 184
             LEC     +   ++ W ++G+ L    D ++   +    L IQ ++  D G Y C A N
Sbjct: 4821 RLECQVDEDT-GVSIIWMRDGKKLHTTMDCKLAFEEKIACLDIQKSKLKDTGTYTCTAAN 4879

Query: 185  AAGTRESAIATLKIHIKPYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
             AG+  S  +++ +   P  +   E  ++ + G S    C V G P   V W  +    N
Sbjct: 4880 EAGS-SSCSSSVTVQEPPVFVKRLEPKILWKQGMSSRLSCTVKGSPELHVTWFLNDKPLN 4938

Query: 244  MPLGRVKV---LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
                + K+    +  +L + ++  +D G Y+CE  N  G  S S  +TV +PP+      
Sbjct: 4939 SS-EKHKITFKTNQATLEIIDLSESDSGNYTCEVMNEAGCESCSSQVTVKEPPAFKKELR 4997

Query: 301  SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
             V V  G  A   C  TG     + W  + N     P  S  KY+  +  +    L I  
Sbjct: 4998 LVEVVKGCTAHLECEMTGTAPFEITWFKDKN-----PVSSDTKYNIVSK-ETAAYLEIKT 5051

Query: 361  TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD-RPPPIITNGPSNQTLPIKSMAVFPC 419
             +  D  +   C + +        GK+T  +    + PP       N T  + S      
Sbjct: 5052 FESADVGDYQCCISNDV-------GKITTKAVAKLKDPPSFVKKVENTTAVLGSAVKLQG 5104

Query: 420  TAICTPEPIIAWYFEGEALIQNHRRNVT-----NDGTLVLKDLDKSDSGTYTCVASSRHG 474
            T I    PI   +F+   ++++   N+T     N   L + ++  +  G YTC A +  G
Sbjct: 5105 T-IKGSAPITVQWFKDTEIVRDDDPNITTTFENNIAVLAISNVAINHGGKYTCQAENEAG 5163

Query: 475  KYVWSGALLVDSP 487
            K      + V  P
Sbjct: 5164 KQKCEATVTVQEP 5176



 Score =  119 bits (286), Expect = 6e-25
 Identities = 128/485 (26%), Positives = 198/485 (40%), Gaps = 37/485 (7%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
            +T  E P   + P  V   + + A+LNC   GS    I W+K    +        +  G 
Sbjct: 6555 LTIKEPPSFYKLPTPVEGLKGKDASLNCELKGSAPFEITWFKDKKQLKESRKYKFVSEGC 6614

Query: 66   LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGD 123
               L    G   SDAG Y C+ATN+ G+   + +      LRE   F  +  +  +  G+
Sbjct: 6615 SATLHIL-GLEASDAGEYECKATNNVGSDLCQGS----VKLREPPAFVKKLSNTTAISGE 6669

Query: 124  TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ--DARQTDAGRYQCI 181
             VVL     +GS    V W ++   +L DG++R    +   + ++   A  T AG+Y C 
Sbjct: 6670 EVVL-LTTVKGSQPMTVSWVQDKDHILRDGENRKITFENNEVTLKVFKADSTTAGKYTCQ 6728

Query: 182  ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRS-- 238
             +N AG  E   A L + ++P  I    D ++ T G +   +C V G P     W +   
Sbjct: 6729 LKNDAGVAE-CTANLTV-LEPAAIVDKTDSISVTAGEAAALECTVSGTPELKPKWFKDGV 6786

Query: 239  --AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PP 293
              + G    +   K++   SL+L +   +D GEY+   +N VG+ S +  LTV D   PP
Sbjct: 6787 ELSSGKKYKITFSKMI--SSLKLLSTERSDTGEYTFSIKNEVGSDSCAMQLTVLDKIVPP 6844

Query: 294  SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
              +          G      C A+G    T+ W    N   I   MS   Y  T   +  
Sbjct: 6845 LFSRKLKDTQSIVGKSMELDCKASGSAPLTISWF--HNEVEI---MSGPNYEITFT-ENT 6898

Query: 354  TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413
              L +     +DS  T  C AVN AG++     L V      PP  +T     + LP  +
Sbjct: 6899 CTLKVPTLKLSDS-GTYKCKAVNSAGAAETSASLVV----KEPPSFVTTPQPVEALP-GT 6952

Query: 414  MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVAS 470
               F  T   +    + W+   + ++      +   G    L L ++DKS +G YTC   
Sbjct: 6953 TVTFTATVQGSTPMKLKWFRGSKEIVSGRSCEIALRGDTAILELHNIDKSHAGEYTCQII 7012

Query: 471  SRHGK 475
            +  GK
Sbjct: 7013 NDAGK 7017



 Score =  116 bits (279), Expect = 4e-24
 Identities = 105/415 (25%), Positives = 164/415 (39%), Gaps = 21/415 (5%)

Query: 81   GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
            G Y CEA    G   + +    +  +   FR   ++ +   G +   EC     +P    
Sbjct: 4588 GEYTCEAVGEAGKTSTSSHLTVIPRVPPVFRQRIQNLEVNVGSSAKFEC-EIEEAPGVTF 4646

Query: 141  YWKKNGQTLLFDGDSRM-HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE-SAIATLKI 198
             W K+G  L      R+       +L I      D+G Y C A N  G+   SA  T+  
Sbjct: 4647 KWFKSGTELRHSEKCRIISRHHTSSLEIFSPAVADSGEYTCKASNRHGSDSCSAKLTVTE 4706

Query: 199  HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLR 258
               P  ++ P+ +    G    FQC + G    +V+W +     ++     +  D     
Sbjct: 4707 LFPPEFVSKPDSMTLFVGKQAKFQCVISGSEPMNVVWHKDNIAISLDDHYKESSDKNRYF 4766

Query: 259  LD--NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316
            L+  N+  +D+G Y C+A NSVG  +    L V D PS   S  S  V  GN  R  C  
Sbjct: 4767 LEILNLQHSDQGTYLCKASNSVGTATCCTELRVVDKPSFVKSFESTTVAVGNPLRLECQV 4826

Query: 317  TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
                  ++ W  +G +      +        A  + +  L I  +   D+  T  C+A N
Sbjct: 4827 DEDTGVSIIWMRDGKK------LHTTMDCKLAFEEKIACLDIQKSKLKDT-GTYTCTAAN 4879

Query: 377  YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEG 435
             AGSS     +TV     + PP+       + L  + M+    CT   +PE  + W+   
Sbjct: 4880 EAGSSSCSSSVTV-----QEPPVFVKRLEPKILWKQGMSSRLSCTVKGSPELHVTWFLND 4934

Query: 436  EALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
            + L  + +  +   TN  TL + DL +SDSG YTC   +  G    S  + V  P
Sbjct: 4935 KPLNSSEKHKITFKTNQATLEIIDLSESDSGNYTCEVMNEAGCESCSSQVTVKEP 4989



 Score =  108 bits (260), Expect = 8e-22
 Identities = 118/468 (25%), Positives = 183/468 (39%), Gaps = 31/468 (6%)

Query: 31   LNCRAGGSPSPAIRWYKGGVLVVSDT-HRSIL--PAGGLFFLRATHGRVHSDAGVYWCEA 87
            L C   GS    + W+K    + +D  H+ I    A  L   R       SD+G Y C A
Sbjct: 5758 LECLVSGSLPINVTWFKENKEIEADEKHKCIFFENAASLEISRLDS----SDSGNYTCIA 5813

Query: 88   TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
             N  G+ +  + TL V         +PES+    G  V    L   G+P   + W K+ +
Sbjct: 5814 KNQAGSDQC-SGTLKVKEPPSIIE-KPESQDVIPGSKVQFNVLLS-GTPPLTINWFKDTK 5870

Query: 148  TLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT 206
             +    D  +   D   ++ +  A+ +D+G+Y C   N  G+ +S  ATL +   P    
Sbjct: 5871 EVSSGIDCSVQKNDTSSSIELFFAKPSDSGQYVCEVSNDVGS-DSCQATLFVKEPPKFTR 5929

Query: 207  GPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVI-- 263
             PE + V +    V F+C++ G P  D  W +  G    P  + K+    SL    +I  
Sbjct: 5930 KPEKITVVKPSQLVVFECQITGTPEIDTYWFKD-GNDISPSDKYKMTFVDSLARLEIISS 5988

Query: 264  -LADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEP 322
             + D G Y CEA N  G+ S S  L V +PP +    + + V +G+ A F C   G    
Sbjct: 5989 DIKDSGVYYCEARNEAGSESCSMDLRVKEPPVLVKPLSPLEVVNGSNAYFECLVKGTAPF 6048

Query: 323  TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
             + W  +          S  K+      D +  L +   D  D      C   N  GS  
Sbjct: 6049 EVTWEKDSKDI-----KSSLKHVILQKNDSIITLDVQKCDALDV-GEYQCIVANEVGSCS 6102

Query: 383  VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN- 441
             +  L++     + PP       N    +  M  F C    +P   I W  +   ++++ 
Sbjct: 6103 SQSTLSI-----KEPPSFVERIENVVTVLGKMVEFKCVVRGSPPLSIQWQKDESWILEDP 6157

Query: 442  --HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
               R    N  TL +   +   SG YTC A +  G+      L+V  P
Sbjct: 6158 SIQRTFENNVATLTIPVCESIHSGKYTCQAMNEAGQEKCFSTLVVQEP 6205



 Score =  108 bits (259), Expect = 1e-21
 Identities = 111/490 (22%), Positives = 199/490 (40%), Gaps = 31/490 (6%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-THRSILPAGGLFF 68
            E P  +++  + T    +   L     GS    + W +    ++ D  +R I        
Sbjct: 6652 EPPAFVKKLSNTTAISGEEVVLLTTVKGSQPMTVSWVQDKDHILRDGENRKITFENNEVT 6711

Query: 69   LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVL 127
            L+       + AG Y C+  N  G A     T ++ VL     ++  +S     G+   L
Sbjct: 6712 LKVFKAD-STTAGKYTCQLKNDAGVAE---CTANLTVLEPAAIVDKTDSISVTAGEAAAL 6767

Query: 128  ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAA 186
            EC    G+PE    W K+G  L      ++       +L +    ++D G Y    +N  
Sbjct: 6768 ECTVS-GTPELKPKWFKDGVELSSGKKYKITFSKMISSLKLLSTERSDTGEYTFSIKNEV 6826

Query: 187  GTRESAIA-TLKIHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA----G 240
            G+   A+  T+   I P L +   +D  +  G S+   C+  G     + W  +      
Sbjct: 6827 GSDSCAMQLTVLDKIVPPLFSRKLKDTQSIVGKSMELDCKASGSAPLTISWFHNEVEIMS 6886

Query: 241  GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
            G N  +   +  +  +L++  + L+D G Y C+A NS GA   S  L V +PPS   +P 
Sbjct: 6887 GPNYEITFTE--NTCTLKVPTLKLSDSGTYKCKAVNSAGAAETSASLVVKEPPSFVTTPQ 6944

Query: 301  SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
             V    G    FT T  G     + W   G++ I+  G S +     A+     +L +++
Sbjct: 6945 PVEALPGTTVTFTATVQGSTPMKLKW-FRGSKEIV-SGRSCE----IALRGDTAILELHN 6998

Query: 361  TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
             DK+ +     C  +N AG       L V     +          N ++ +    +  CT
Sbjct: 6999 IDKSHA-GEYTCQIINDAGKENCPVNLFV-----KEAAHFVKKLKNLSVEMGKSLILECT 7052

Query: 421  AICTPEPIIAWYFEGEALIQNHRRNV-TNDGTLVLKDL--DKSDSGTYTCVASSRHGKYV 477
               +P+ ++ W+ +G+ +  +++ N+ T + + +L+ L  DK  +G YTC  S+  G  +
Sbjct: 7053 YAGSPKILVKWHKDGQEIYSSYKYNITTTESSCILECLNSDKEAAGKYTCEVSNDAGHDI 7112

Query: 478  WSGALLVDSP 487
               A+ +  P
Sbjct: 7113 CEAAVSILEP 7122



 Score =  107 bits (256), Expect = 2e-21
 Identities = 117/495 (23%), Positives = 190/495 (38%), Gaps = 35/495 (7%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQ--PATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
            VT  E P  +++ L+  +   Q   + L+C   GSP   + W+     + S     I   
Sbjct: 4890 VTVQEPPVFVKR-LEPKILWKQGMSSRLSCTVKGSPELHVTWFLNDKPLNSSEKHKITFK 4948

Query: 64   GGLFFLRATHGRVHSDAGVYWCEATNSYG--TARSRNATLHVAVLREEFRLEPESKQSAQ 121
                 L        SD+G Y CE  N  G  +  S+         ++E RL     +  +
Sbjct: 4949 TNQATLEIID-LSESDSGNYTCEVMNEAGCESCSSQVTVKEPPAFKKELRLV----EVVK 5003

Query: 122  GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD---GGNLVIQDARQTDAGRY 178
            G T  LEC    G+    + W K+   +    D++ ++V       L I+     D G Y
Sbjct: 5004 GCTAHLEC-EMTGTAPFEITWFKDKNPV--SSDTKYNIVSKETAAYLEIKTFESADVGDY 5060

Query: 179  QCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238
            QC   N  G + +  A  K+   P  +   E+  A  GS+V  Q  + G     V W + 
Sbjct: 5061 QCCISNDVG-KITTKAVAKLKDPPSFVKKVENTTAVLGSAVKLQGTIKGSAPITVQWFKD 5119

Query: 239  AGGGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295
                      +    + +   L + NV +   G+Y+C+AEN  G       +TV +P   
Sbjct: 5120 TEIVRDDDPNITTTFENNIAVLAISNVAINHGGKYTCQAENEAGKQKCEATVTVQEPARF 5179

Query: 296  NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
               P  ++V +G+ A   C  +G P+  + W  +G        M+  + +     + V V
Sbjct: 5180 VEKPPCISVTAGDSATLECKVSGSPDLKVKWFKDGKE------MAGGRKYKITFKENVAV 5233

Query: 356  LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
            L I   ++ DS    V    N  G       + V       PP+ +  P +Q +   +  
Sbjct: 5234 LKILSAERGDSSEYKV-EVSNRVGKEQCSCSINVLE-----PPVFSLKPQSQDVIPGTTV 5287

Query: 416  VFPCTAICTPEPIIAWYFEGEALIQNHR---RNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
            V       T   +I W+ E + ++       +  TN  +L L  L  S S  YTC  S+ 
Sbjct: 5288 VLTAAFTGTAPFMIKWFREDKEMLTGGTCFIKKETNSSSLELHALKPSQSAKYTCQVSND 5347

Query: 473  HGKYVWSGALLVDSP 487
             GK   + AL V  P
Sbjct: 5348 AGKVSCTAALFVKEP 5362



 Score =  107 bits (256), Expect = 2e-21
 Identities = 121/496 (24%), Positives = 190/496 (38%), Gaps = 29/496 (5%)

Query: 3    DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
            D  VT  E P  +++  +  V   +  +L C   GS    I W K    +    H  I  
Sbjct: 5541 DFLVTMKEPPSFVQKMDNTNVLLAKDVSLQCVLKGSMPMTISWMKDDHEIKESEHVQISF 5600

Query: 63   AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122
                  +  +  ++    G Y C A N  G   S+  T  V  ++E   +  ++K  +  
Sbjct: 5601 ENQTAVIYISSVQL-KHGGKYTCHAQNEAG---SQKCTA-VLTVKEPANITEQAKSVSVT 5655

Query: 123  --DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQ 179
              D   LEC    G+      W K+G  L      ++   D  +++ I  A ++DAG Y 
Sbjct: 5656 VRDPATLECRYS-GTKVLKAKWLKDGNELTSGRKYKIQSSDTSSILKILSAEKSDAGEYT 5714

Query: 180  CIARNAAGTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
                N AG    E+ +  L   IKP      ++  +  GS    +C V G    +V W +
Sbjct: 5715 FEVSNDAGRSSCEAVVTVLDQIIKPSFTRKLKETESIKGSFTQLECLVSGSLPINVTWFK 5774

Query: 238  SAGGGNMPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295
                         +  +   SL +  +  +D G Y+C A+N  G+   SG L V +PPSI
Sbjct: 5775 ENKEIEADEKHKCIFFENAASLEISRLDSSDSGNYTCIAKNQAGSDQCSGTLKVKEPPSI 5834

Query: 296  NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
               P S +V  G+  +F    +G P  T+ W  +          S  K   ++    + +
Sbjct: 5835 IEKPESQDVIPGSKVQFNVLLSGTPPLTINWFKDTKEVSSGIDCSVQKNDTSS---SIEL 5891

Query: 356  LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS-M 414
                 +D        VC   N  GS   +  L V     + PP  T  P   T+   S +
Sbjct: 5892 FFAKPSDSGQ----YVCEVSNDVGSDSCQATLFV-----KEPPKFTRKPEKITVVKPSQL 5942

Query: 415  AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL---DKSDSGTYTCVASS 471
             VF C    TPE    W+ +G  +  + +  +T   +L   ++   D  DSG Y C A +
Sbjct: 5943 VVFECQITGTPEIDTYWFKDGNDISPSDKYKMTFVDSLARLEIISSDIKDSGVYYCEARN 6002

Query: 472  RHGKYVWSGALLVDSP 487
              G    S  L V  P
Sbjct: 6003 EAGSESCSMDLRVKEP 6018



 Score = 89.4 bits (212), Expect = 5e-16
 Identities = 112/476 (23%), Positives = 179/476 (37%), Gaps = 29/476 (6%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            + P  +++  + T        L     GS    ++W+K   +V  D             +
Sbjct: 5081 DPPSFVKKVENTTAVLGSAVKLQGTIKGSAPITVQWFKDTEIVRDDDPNITTTFENNIAV 5140

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
             A      +  G Y C+A N  G  +   AT+ V      F  +P       GD+  LEC
Sbjct: 5141 LAISNVAINHGGKYTCQAENEAGKQKCE-ATVTVQE-PARFVEKPPCISVTAGDSATLEC 5198

Query: 130  LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGT 188
                GSP+  V W K+G+ +      ++   +    L I  A + D+  Y+    N  G 
Sbjct: 5199 -KVSGSPDLKVKWFKDGKEMAGGRKYKITFKENVAVLKILSAERGDSSEYKVEVSNRVG- 5256

Query: 189  RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGGGNM 244
            +E    ++ +   P     P+      G++V       G     + W R       GG  
Sbjct: 5257 KEQCSCSINVLEPPVFSLKPQSQDVIPGTTVVLTAAFTGTAPFMIKWFREDKEMLTGGTC 5316

Query: 245  PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN- 303
             +   K  +  SL L  +  +   +Y+C+  N  G VS +  L V +PP   +  +    
Sbjct: 5317 FIK--KETNSSSLELHALKPSQSAKYTCQVSNDAGKVSCTAALFVKEPPKFVMKLDLTKL 5374

Query: 304  VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
            V +G++A   C   G PE ++ W    N T I    S DKY   A  D V  L I+    
Sbjct: 5375 VLNGSLATLECKVAGSPEISIRW--YKNETEI---GSDDKYQ-MAFTDSVATLRISSCCV 5428

Query: 364  NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
             DS    +C A + AGS      +TV      PP  +    S +   +K   V     + 
Sbjct: 5429 EDS-GDYICQASSDAGSDRCSCLVTV----KEPPEFVKPFESKEI--VKGTDVVLEGTVS 5481

Query: 424  TPEPIIAWYFEGEALIQNHRRNV---TND-GTLVLKDLDKSDSGTYTCVASSRHGK 475
               P     F+    I+N RR++   T D   L +   +  D+G Y C   +  G+
Sbjct: 5482 GSAPFEISCFKDSKQIRNDRRHIISLTKDVAALQILKFEPGDAGKYQCTVGNEVGQ 5537



 Score = 83.8 bits (198), Expect = 3e-14
 Identities = 113/490 (23%), Positives = 186/490 (37%), Gaps = 52/490 (10%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            E P  +E+  +V     +     C   GSP  +I+W K    ++ D          +  L
Sbjct: 6111 EPPSFVERIENVVTVLGKMVEFKCVVRGSPPLSIQWQKDESWILEDPSIQRTFENNVATL 6170

Query: 70   RA-THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
                   +HS  G Y C+A N  G  +  + TL V    +    +PE      GD V  E
Sbjct: 6171 TIPVCESIHS--GKYTCQAMNEAGQEKCFS-TLVVQEPPQIIE-KPEVINVTAGDPVSFE 6226

Query: 129  CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAG 187
            C    G+PE  V W K+G+ ++      +  ++    L +Q  +  D G Y     N   
Sbjct: 6227 C-KVSGTPELKVKWSKDGKEVIPSRQHSLSYINNVSQLKLQSVQLEDKGTYVFEVSNHIS 6285

Query: 188  TRESAIA--TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
              +  +    L+  I P  I    ++    G +V   C++ G     V W +    G   
Sbjct: 6286 ACQCKVTLNVLEQIIPPSFIKPLMEMEEIIGKNVQIGCKISGSLPITVEWEKD---GTKL 6342

Query: 246  LGRVK---VLDDGSLRLDNVIL--ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
             GR K   + D+ S+ LD   L  AD G Y+C+  N  G+   SG L V +  ++   PN
Sbjct: 6343 SGRTKHKILQDENSVSLDIECLEKADTGTYTCKLANKAGSCECSGTLRVKESQAV--IPN 6400

Query: 301  SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
            +         RF  +  G P  T+ W  +    I  P          + F G+  L+   
Sbjct: 6401 T-------TVRFKGSFKGTPPFTVKWFKDDTELICGP----------SCFTGLEGLS--- 6440

Query: 361  TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
                     +    ++++G+   +      S+D  PP  +   P+ + + +       C 
Sbjct: 6441 -----CFLDLFAVGISHSGTYSCQ-----ISNDAEPPEFVQKLPAAKVVKMGEPLQLECK 6490

Query: 421  AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS---DSGTYTCVASSRHGKYV 477
               T    I+WY     L       +T D ++ + ++  S   D+G YTC A +  G   
Sbjct: 6491 VTGTAPLRISWYKNDAILSDGGNLRMTFDNSVAVLEISTSSFDDNGVYTCEAQNDAGTKS 6550

Query: 478  WSGALLVDSP 487
             S AL +  P
Sbjct: 6551 CSTALTIKEP 6560



 Score = 79.4 bits (187), Expect = 6e-13
 Identities = 81/284 (28%), Positives = 117/284 (41%), Gaps = 22/284 (7%)

Query: 253  DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PPSINLSPNSVNVESGNVA 310
            D  +L +  V+   EGEY+CEA    G  S S +LTV    PP       ++ V  G+ A
Sbjct: 4573 DTYTLVITKVMKDHEGEYTCEAVGEAGKTSTSSHLTVIPRVPPVFRQRIQNLEVNVGSSA 4632

Query: 311  RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
            +F C     P  T  W   G              H T      + L I      DS    
Sbjct: 4633 KFECEIEEAPGVTFKWFKSGTELRHSEKCRIISRHHT------SSLEIFSPAVADS-GEY 4685

Query: 371  VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-I 429
             C A N  GS     KLTVT   +  PP   + P + TL +   A F C  I   EP+ +
Sbjct: 4686 TCKASNRHGSDSCSAKLTVT---ELFPPEFVSKPDSMTLFVGKQAKFQC-VISGSEPMNV 4741

Query: 430  AWYFEGEAL-IQNHRRNVTNDGTLVLK--DLDKSDSGTYTCVASSRHGKYVWSGAL-LVD 485
             W+ +  A+ + +H +  ++     L+  +L  SD GTY C AS+  G       L +VD
Sbjct: 4742 VWHKDNIAISLDDHYKESSDKNRYFLEILNLQHSDQGTYLCKASNSVGTATCCTELRVVD 4801

Query: 486  SPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
             P    +  F +  V+   G P +       DT V++ W ++ K
Sbjct: 4802 KP--SFVKSFESTTVA--VGNPLRLECQVDEDTGVSIIWMRDGK 4841



 Score = 73.7 bits (173), Expect = 3e-11
 Identities = 80/287 (27%), Positives = 113/287 (39%), Gaps = 25/287 (8%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH-S 78
            ++TV   Q +T             RW + GV +     +    A      R T    + S
Sbjct: 2929 EITVLEKQRSTFEFEVNEDDIEG-RWLRNGVEIQFSVDQRFNYAIIRKIHRLTITETYRS 2987

Query: 79   DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
            DAG Y    T   G  RS   TLHV +      +      S +        +   G P+P
Sbjct: 2988 DAGEY----TFIAGKNRSI-VTLHVNIPEPPQIIRHMQPLSVEAGKPARFSVEVTGIPQP 3042

Query: 139  NVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
             V W KN Q L   G     L +G    L++ +    DA +Y C A+N  G   S+ A+L
Sbjct: 3043 QVSWYKNSQALS-SGFKCKFLREGNEHTLLLIEVFPEDAAQYNCEAKNDYGVATSS-ASL 3100

Query: 197  KIHIK-------------PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
             + +              P ++T  ++  A  G S  FQCRV G+ L    + +      
Sbjct: 3101 NVEVPEVVSPDTGAPLSPPVVLTPIQNTSANEGQSARFQCRVSGEDLTITWYCKDKEIKQ 3160

Query: 244  MPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
              + RV   D+   L +  V   DEGEY+C A NS G VS S  L V
Sbjct: 3161 SDIFRVSQFDENCQLEITRVYPEDEGEYTCVARNSAGMVSCSALLKV 3207



 Score = 73.3 bits (172), Expect = 4e-11
 Identities = 112/450 (24%), Positives = 170/450 (37%), Gaps = 47/450 (10%)

Query: 178   YQCIARNAAGTRESAIATLK-IHIKPYLITGPEDVVAQTGSSVTFQCRV----GGDPLPD 232
             ++ IA N AG  + +  T   + + P    G  DV+  T +SVT         GG  L  
Sbjct: 19884 FRVIAINVAGLGKPSRTTESLVALDPIDPPGKPDVINVTRNSVTLMWTAPKYDGGHKLTG 19943

Query: 233   VLWRRSAGGGN--MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV- 289
              +  +    G   M    V V    +  + ++      E+   A+N+ GA+SA    T  
Sbjct: 19944 YMVEKLEHPGKTWMKANHVNV-QSCAYTVTDLQEGCTCEFRIRAKNAAGAISAPSETTEP 20002

Query: 290   ------YDPPSINLSP---NSVNVESGNVARFTCTAT-GRPEPTMFWSVEGNRTIIFPGM 339
                   Y+PP+I + P   + V V++G     T ++  G+P PT  WS  G         
Sbjct: 20003 LVCKDEYEPPTITIDPEMKDGVTVKAGGTIVITASSILGKPPPTAVWSKAGREF-----K 20057

Query: 340   SRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPI 399
             S D    ++     T+     + KN    TI  S  N  G    + K+ V      P PI
Sbjct: 20058 SSDIVQISSTPTSSTLSIKYASRKNTGEYTITAS--NPFGIKDEKVKVKVLDVPGPPGPI 20115

Query: 400   ITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDK 459
               +  S +   +  +        C+ +  I    E   L+         D   V   L K
Sbjct: 20116 EASSVSAEKCTLTWLPPEEDGG-CSIKSYILEKRETSRLLWTKLAENVMDCRYVASKLIK 20174

Query: 460   SDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTS 519
              +   +   A +++G    +G +    P+       +  D    PGPP+KP   NV+  +
Sbjct: 20175 GNEYIFRVSAVNQYG----TGDVTQSGPV-------KMVDSFGPPGPPSKPEIDNVSKNA 20223

Query: 520   VTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIP 579
             VT+SW +    G S I GY VE   R+   G    R S+      + V    + V  L  
Sbjct: 20224 VTISWKRPTVDGGSDIRGYIVE---RKERRGMRWVRASK------KTVSDLRFKVSGLSE 20274

Query: 580   GITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
              I Y F V  EN  G   PS  S  V   D
Sbjct: 20275 EIEYEFRVTAENKAGFGEPSEPSQPVMTKD 20304



 Score = 72.9 bits (171), Expect = 5e-11
 Identities = 125/524 (23%), Positives = 196/524 (37%), Gaps = 78/524 (14%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
            D+ V   + A   C     P+  + W K G  +       +     +  L     R+ SD
Sbjct: 2839 DIKVTEKKKAVFECELS-EPNVQVTWMKDGQELELSERYKVSTERHVHRLMIQTVRM-SD 2896

Query: 80   AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPE-SKQSAQGDTVVLECLPPRGSPEP 138
            AG Y   A +S   A   N T+    +R     E E +    Q  T   E        + 
Sbjct: 2897 AGEYSVVAGSSVSKA---NLTVEGKDVRISEPAEKEITVLEKQRSTFEFEV----NEDDI 2949

Query: 139  NVYWKKNGQTLLFDGDSRMHLV---DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195
               W +NG  + F  D R +         L I +  ++DAG Y  IA      +  +I T
Sbjct: 2950 EGRWLRNGVEIQFSVDQRFNYAIIRKIHRLTITETYRSDAGEYTFIAG-----KNRSIVT 3004

Query: 196  LKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD 253
            L ++I   P +I   + +  + G    F   V G P P V W +++   +    + K L 
Sbjct: 3005 LHVNIPEPPQIIRHMQPLSVEAGKPARFSVEVTGIPQPQVSWYKNSQALSSGF-KCKFLR 3063

Query: 254  DGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP------------PSINLS 298
            +G+   L L  V   D  +Y+CEA+N  G  ++S  L V  P            P + L+
Sbjct: 3064 EGNEHTLLLIEVFPEDAAQYNCEAKNDYGVATSSASLNVEVPEVVSPDTGAPLSPPVVLT 3123

Query: 299  P-NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
            P  + +   G  ARF C  +G  + T+ W  +         + +      + FD    L 
Sbjct: 3124 PIQNTSANEGQSARFQCRVSGE-DLTITWYCKDKE------IKQSDIFRVSQFDENCQLE 3176

Query: 358  INDTDKNDSRNTIVCSAVNYAG----SSFVR--GKLTVTSDDDRPPPIITNGP--SNQTL 409
            I      D      C A N AG    S+ ++  G+  V     + PP  T+ P  S +T+
Sbjct: 3177 ITRVYPED-EGEYTCVARNSAGMVSCSALLKVDGETEVMDYSSKFPPQATSSPLTSIKTI 3235

Query: 410  -------------PIKSMAV-------FPCTAICTPEPIIAWYFEGEAL-----IQNHRR 444
                         PI S  V       F       P+P I+W+   + +     +  H  
Sbjct: 3236 QKDAIGQKPSFFQPIMSSVVAHGEVARFHACVSGIPKPEISWFHNQQPIKPTKNVVYHFD 3295

Query: 445  NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPI 488
             +TN  TL++ D     +G YTC A +  G+   S  L V   +
Sbjct: 3296 EMTNTATLIIVDTFSEHAGQYTCKAVNIRGEAACSANLAVTEEV 3339



 Score = 72.1 bits (169), Expect = 8e-11
 Identities = 116/475 (24%), Positives = 170/475 (35%), Gaps = 52/475 (10%)

Query: 10    EAPYI-IEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
             E PY+   +PL DV V   + A   C      S  +RW++ G  +       ++  G   
Sbjct: 12086 EPPYVEFTKPLHDVEVKEKESARFECEVSRE-SAKVRWFRDGNEIRKGKKYEMISEGVKR 12144

Query: 68    FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPE--SKQSAQGDTV 125
              L  +   V  D   Y C+A  S  +         + V+ EE R      + +  + D+V
Sbjct: 12145 ILIISKS-VFDDEAEYECDARTSKSSGM-------LTVVEEEARFTKNLANIEGTETDSV 12196

Query: 126   VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIAR 183
              L C   + S E  V W K  Q L   G    H+ DG    L+I+  R  DAG Y C   
Sbjct: 12197 KLICEVSKPSAE--VTWYKGDQELPEVGRYE-HITDGKKRILIIKGLRMDDAGEYHCKLP 12253

Query: 184   NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
              +  T    I  L        I  P++     G    F C V  D   +V W +    GN
Sbjct: 12254 TSQTTGNLRINELAAEF----IARPQNQEVVEGEKAQFVCSVSKDTY-EVKWLK----GN 12304

Query: 244   MPL---GRVKVLDDGSLRL---DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
               L    + +++ +G  R+    N  L DEG +       +G   AS  LTV +   I  
Sbjct: 12305 TELQSDDKYEIISEGKKRVLIVKNCELKDEGGFVV----LIGTTRASADLTVLEKLRIIT 12360

Query: 298   SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
                      G      C           W ++ N T+        K+      D V  L 
Sbjct: 12361 PLKDTKANEGQETVLNCEVNTEGAKAK-W-LKNNETLF----ESSKFIMVQK-DNVFSLR 12413

Query: 358   INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
             I DT K+D  N  +      A  +     +TV  +D R    I   P +     K    F
Sbjct: 12414 IKDTQKSDEANYTITLTNQRAEQAKSSANITVHEEDLR----IVVPPEDVDTQEKKAISF 12469

Query: 418   PCTAICTPEPIIAWYFEGEALIQNHR---RNVTNDGTLVLKDLDKSDSGTYTCVA 469
              C  +      + W   G+ +  + R   R      TL +KD   +D G YT +A
Sbjct: 12470 TCK-VNRQNVTVQWMKAGQEITLSKRILYRVDKEKHTLTIKDCSLADEGEYTVIA 12523



 Score = 70.1 bits (164), Expect = 3e-10
 Identities = 78/306 (25%), Positives = 119/306 (38%), Gaps = 39/306 (12%)

Query: 310   ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
             A F     G P+P + W   G + I+  G    K        G   L I++ D+ND+   
Sbjct: 30578 ATFVTKVVGHPKPVVKWYKNG-KEILADGA---KIKVQEFKGGYFQLVISNADENDAAAY 30633

Query: 370   IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
              +  A N  GS      L V        P+   G          +          P+P++
Sbjct: 30634 QI-RATNQLGSISTSMNLDVEVPAKIYLPLHLQGMGAVHAIRGEVVTIKIPISGKPDPVV 30692

Query: 430   AWYFEGEALIQN---HRRNVTNDGT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
              W  +G+ +I N   H+  +T   T  + LK + + DSG Y   A +R G    +  L  
Sbjct: 30693 TWQ-KGQEIINNTAYHQVIITRSFTSLVFLKGVQRKDSGYYIICAKNRFGMDKQTVEL-- 30749

Query: 485   DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFS 544
                           DV+ +P PP      ++   ++TL+WS  N  G S I+ Y +E   
Sbjct: 30750 --------------DVADVPDPPKDVKVSDIGRDTLTLTWSPGND-GGSEIINYIIE--- 30791

Query: 545   RETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDS 604
                      P     W+ +A+   ++ Y V SL     Y F V  EN  G+S PS  +D 
Sbjct: 30792 -------KCPTTGDRWIRVAQ-TSESQYTVMSLFGKTKYQFRVIAENRFGVSDPSAPTDP 30843

Query: 605   VTVGDD 610
             VT  +D
Sbjct: 30844 VTTKED 30849



 Score = 68.1 bits (159), Expect = 1e-09
 Identities = 104/497 (20%), Positives = 191/497 (38%), Gaps = 22/497 (4%)

Query: 9     GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
             GEAP + E   D T    +   L C+  G P P I+WY+ G  ++      +   G    
Sbjct: 30163 GEAPCLKEDIKDTTTKLGESGILTCQIIGRPLPEIKWYRYGKELIQSRKYKMSSDGRNHS 30222

Query: 69    LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
             L         D G+Y C A N  G   +    L  A  +       + K  A   T +  
Sbjct: 30223 LSVMTDE-QEDEGLYTCRAVNEAGEIETSGKLLLQAAPQFHPGFPLKEKYYAGCGTSLRL 30281

Query: 129   CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDA-RQTDAGRYQCIARNAA 186
              +   G P P + W    + L    +  +   +   +LVI++  R+T+AGRY+    N  
Sbjct: 30282 HVVYIGRPIPQIMWFYGKKPLNPSENVIIENTESYTHLVIRNVQRKTNAGRYKVQLSNKF 30341

Query: 187   GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV----GGDPLPD-VLWRRSAGG 241
             GT ++ +  ++I  KP L  GP  V A   SSV    +     GG  + + ++ +R A  
Sbjct: 30342 GTVDT-VLRVEIQDKPLLPEGPVVVDALLKSSVIISWKPPKDDGGSMITNYIVEKREAKE 30400

Query: 242   GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG---AVSASGYLTVYDPPSINLS 298
             G         +   + R+ N+I +    +   A+N  G   ++     + +  P      
Sbjct: 30401 GEQWHLVSSAVSGTTCRVPNLIESSGYYFRVSAQNQYGISESLEIPSVVIIKSPFEKPGV 30460

Query: 299   PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHA--TAVFDGVTVL 356
             P    V S  V + +C  + +P  +   +   N  +      ++K+ A  T      +  
Sbjct: 30461 PQRPFVSS--VTKDSCVVSWKPPTSDGGAKIKNYFLEKREKKQNKWIAVTTGEIHETSYT 30518

Query: 357   TINDTDKNDSRNTIVCSAVNYAGS-SFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
                  +  +    + C  +      S +   +   SD     P   +   +  +  K+ A
Sbjct: 30519 AKGLLEGFEYEFRVKCENIGGESDWSEISEPVIPKSDTALRAPFFKDELRDMCVKYKANA 30578

Query: 416   VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND-----GTLVLKDLDKSDSGTYTCVAS 470
              F    +  P+P++ WY  G+ ++ +  +    +       LV+ + D++D+  Y   A+
Sbjct: 30579 TFVTKVVGHPKPVVKWYKNGKEILADGAKIKVQEFKGGYFQLVISNADENDAAAYQIRAT 30638

Query: 471   SRHGKYVWSGALLVDSP 487
             ++ G    S  L V+ P
Sbjct: 30639 NQLGSISTSMNLDVEVP 30655



 Score = 67.3 bits (157), Expect = 2e-09
 Identities = 185/808 (22%), Positives = 290/808 (35%), Gaps = 82/808 (10%)

Query: 37    GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
             G P+P I W K G  +   T  ++        L+        D+G Y   ATN+ GT   
Sbjct: 23972 GRPTPKIGWMKDGQALKETTRLNVSSTATSTVLKIKEAN-REDSGKYTITATNNIGTVTE 24030

Query: 97    RNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP--RGSPEPNVYWKKNGQTLLFDGD 154
               A   + + +      P          VV+   PP   G  + N Y  +   T   +  
Sbjct: 24031 EVAI--IILDKPGPPTGPVKIDEVSATYVVISWEPPVYTGGCQINNYVVEKRDTTTTNWQ 24088

Query: 155   SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL---ITGPEDV 211
             +    +    + I   +     +++  A N  G   S  +T  +   P+      G   V
Sbjct: 24089 TVSATIARTTIKISKLKTGSEYQFRVFAENRYGKSGSIDSTPVVVSYPFTEPAAPGAPFV 24148

Query: 212   VAQTGSSVTFQCRV----GGDPLPDVLWRRSAGGGNMPLGRVKVL-DDGSLRLDNVILAD 266
              + T   +T + +     GG P+      R      +     K+L  D  LR + +    
Sbjct: 24149 SSVTKDHMTIEWKPPSNNGGSPIIGYHLERKEKNSILWTKLNKLLITDTRLRTNGLEEGI 24208

Query: 267   EGEYSCEAENSVG---AVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPT 323
             E EY   AEN  G   +   S  +   DP     +P ++ V + N+     T       +
Sbjct: 24209 EYEYRVFAENIAGISPSSKVSESVVARDPCDPPGTPEAI-VITRNLITLQWTKPQYDGGS 24267

Query: 324   MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383
             +       R  +  G    K   T + D  T  TI    + + R      A N AG   V
Sbjct: 24268 VITGYIIERKKLPDGRWM-KASFTNIID--TQFTITGLHE-EQRYEFRVIARNAAGILSV 24323

Query: 384   RGKLT--VTSDDD-RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI--IAWYFEGEAL 438
               + T  +T+ D+   P +  +      + +K+   F   +    +P+  I W  +G+ +
Sbjct: 24324 PSESTGPITAQDEIEAPSVSMDSRFKDVIIVKAGDSFSIDSDIAGKPLPDIVWLKDGKEI 24383

Query: 439   IQ-NHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHF 494
                  R  + +  T   L +KD  + D G +    S+  G            PIN     
Sbjct: 24384 DSATPRMEIKSTITRTVLTVKDCIRVDGGHFVLSLSNVGGTK--------QVPIN----- 24430

Query: 495   FRAADVSSLPGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNT 553
                  V   PGPP  P+    V      L WS  +  G +SI  Y +E   RET      
Sbjct: 24431 ---VKVLDRPGPPDGPLKVTGVAAEKCYLHWSHPSHDGGASISHYIIE--KRET------ 24479

Query: 554   PRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNS 613
               +   W V+  ++    Y V  L+PG  Y+F V   N +G+  P   S+ V   +  N 
Sbjct: 24480 --SRLSWTVVEPKIQAISYKVTKLLPGNEYIFRVMAVNKYGIGEPLE-SEPVLAKNPFNK 24536

Query: 614   LWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDN 673
                G     ST   + I  D IV   E    D  +            ++G  +  R  D 
Sbjct: 24537 --PG---PPSTPEASAITRDSIVLTWERPEDDGGS-----------QIDGFVLEKR--DK 24578

Query: 674   ITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN-SRVAQTLD-DVP 731
               I +        ND+  F  T L +   YEF +        G PS  S   +  D   P
Sbjct: 24579 EGIRWTKCNKKRLNDLR-FRATGLTEGHFYEFRVSAENAAGVGTPSEPSEYYKACDATYP 24637

Query: 732   DGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQ 791
              GPP N ++   ++TTV L WS P +      ++GY  +V   D+  ++  V    T  Q
Sbjct: 24638 PGPPNNPKVTDHSSTTVSLAWSRP-IYDGGAPVSGY--IVEAKDINEDEWTVCTPPTGVQ 24694

Query: 792   ATSLIMTNLTSGVSYSVQIAAETIIGLG 819
             AT   +  L     Y+ +I A  I G G
Sbjct: 24695 ATHFTVKKLKENAEYNFRICAVNIEGAG 24722



 Score = 66.5 bits (155), Expect = 4e-09
 Identities = 42/108 (38%), Positives = 52/108 (48%), Gaps = 10/108 (9%)

Query: 496   RAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPR 555
             +A D   LP PP KP   + T TSVTLSW++    G S + GY VE          NT  
Sbjct: 25711 KAEDPLFLPSPPAKPKIIDSTKTSVTLSWNKPLFDGGSPVTGYMVEY--------RNT-- 25760

Query: 556   NSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
             N   W V       T + V  L  G  Y+F+VR+ N  G S PSP +D
Sbjct: 25761 NDDDWTVGVNNTKSTEFTVVGLTSGTEYVFVVRSINKIGPSEPSPETD 25808



 Score = 62.9 bits (146), Expect = 5e-08
 Identities = 99/403 (24%), Positives = 163/403 (40%), Gaps = 59/403 (14%)

Query: 422   ICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVW 478
             +  P+  + W  +G +L +  R N         L+LK+  + D G YT   ++  G+   
Sbjct: 21808 VAQPKAAVVWQKDGISLKETTRVNTEVAERHLYLLLKEATRDDVGKYTIKITNSAGE--- 21864

Query: 479   SGALLVDSPINPNIHFFRAADVSSLPGPPTKPIT-HNVTDTSVTLSWSQNNKIGSSSILG 537
                    + IN          V   PGPPT PI    VT  SVTLSW      G  SI  
Sbjct: 21865 -----ATADIN--------VIVLDKPGPPTGPIKIEEVTADSVTLSWQPPEYEGGCSINN 21911

Query: 538   YQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSG 597
             Y VE   R+T + N        W +++  V +T      L  G  Y F +  EN +G S 
Sbjct: 21912 YIVE--KRDTSTTN--------WQIVSATVARTTTKAARLKTGCEYQFRIAAENRYGKS- 21960

Query: 598   PSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILN 657
              S +     V      +    G+           T   + ++   P      K++     
Sbjct: 21961 -SVIVSEHVVAQYPFEIPHPPGIPAVQS-----ATKESMVVVWNKPSSDGGSKILG---- 22010

Query: 658   FYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGK 717
              Y++E      +  +++    + KTI+     + F+I  L +  +YEF +  + +   G 
Sbjct: 22011 -YHIES-----KEKNSLLWVKQNKTIIPD---TRFKIGGLEEGIEYEFRV--YAENIVGL 22059

Query: 718   PSNSRVAQ-TLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGI-ITGYNVVVNWLD 775
                S+V++  +   P  PP   E  I+  ++V L+W+PP  Q   GI ITGY  VV   +
Sbjct: 22060 SKASKVSEIQVARDPCDPPGKPEAVIVKRSSVTLRWTPP--QFDGGIKITGY--VVEKKE 22115

Query: 776   VPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGL 818
             +P  + M A    + + T  +++ L     Y  ++ A    G+
Sbjct: 22116 LPNGRWMKASFANIIE-TEFVVSGLVEEQQYEFRVIARNAAGV 22157



 Score = 62.9 bits (146), Expect = 5e-08
 Identities = 53/176 (30%), Positives = 77/176 (43%), Gaps = 30/176 (17%)

Query: 425   PEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
             P+P I W  +G AL Q  R NV +     TL +KD  + D G Y  V ++  G+   +  
Sbjct: 22892 PKPTITWNKDGSALKQTTRVNVADTAHHTTLTIKDATREDGGMYNIVVANVLGQQEATVE 22951

Query: 482   LLVDSPINPNIHFFRAADVSSLPGPPTKPIT-HNVTDTSVTLSWSQNNKIGSSSILGYQV 540
             +++                   PGPPT P+    V+  S+TLSW      G   I  Y V
Sbjct: 22952 III----------------LEKPGPPTGPVRIDEVSAESITLSWDPPTYTGGCQISNYIV 22995

Query: 541   EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
             +   R+T + N        WVV++  V +T   V +L  G  Y F +  EN +G S
Sbjct: 22996 Q--KRDTTTTN--------WVVVSATVARTTLKVGNLKTGAEYQFRIFAENRYGKS 23041



 Score = 61.7 bits (143), Expect = 1e-07
 Identities = 83/303 (27%), Positives = 121/303 (39%), Gaps = 34/303 (11%)

Query: 304   VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
             V++G+  R      G P PT  W ++G   I   G ++     T  F   TVL+I D  +
Sbjct: 17191 VKAGSTIRLPALMRGLPVPTAKWVIDGEE-IKSEGNTKID---TDNFS--TVLSIADCTR 17244

Query: 364   NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN--QTLPIKSMAVFPCTA 421
             N +    + +  N AGS  V   L VT  D    PI   GP N  +  P   +  +    
Sbjct: 17245 NHT-GIYILTVSNSAGSKTV--SLNVTVLDVPAAPI---GPVNILEVTPDSMVIDWRPPK 17298

Query: 422   ICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
                  P++ +  E     +     V++  T     + +   G    V      K +  GA
Sbjct: 17299 DDGGSPVMNYIVEKRESNKETWGGVSSGSTSTRLKISRLQQGVEYVVRIRAENK-MGIGA 17357

Query: 482   LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541
              L  +P     H F A      PG P KP+  ++++ ++TL W+     G S I GY +E
Sbjct: 17358 ALESAPTVAR-HQFEA------PGHPGKPVASDLSEDALTLGWTMPLFDGGSPISGYIIE 17410

Query: 542   VFSRETLSGNNTPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600
                R    G         W+ + +    +  Y V  L  G  Y F V  EN  G SGPSP
Sbjct: 17411 ---RRHKGGK--------WIRVNKTPCKELRYRVLGLFEGNEYEFRVFAENIAGFSGPSP 17459

Query: 601   VSD 603
             VSD
Sbjct: 17460 VSD 17462



 Score = 61.7 bits (143), Expect = 1e-07
 Identities = 48/171 (28%), Positives = 76/171 (44%), Gaps = 6/171 (3%)

Query: 114   PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQ 172
             P+S   A+  T V   +P  G P P V WKK   TL   G   +        L+I+D  +
Sbjct: 19659 PDSSYVAKEGTTVRLNIPITGIPAPAVIWKKGDVTLSDSGRISVESTTTNTVLLIRDCHR 19718

Query: 173   TDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV----GGD 228
              DAG++  I RN+AGT+E+AI  +K+  KP + +GP      T  ++T +       GG 
Sbjct: 19719 GDAGKFTIILRNSAGTKEAAI-DIKVVGKPGICSGPIKFDEITAEAITVEWGPPKDDGGS 19777

Query: 229   PLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279
              + +    +     N  +     +   S+R+  +    E  +   AEN  G
Sbjct: 19778 EVTNYFLEKRHSTANKWVTVASAIQKNSMRVTRLHDGTEYIFRVCAENKYG 19828



 Score = 61.3 bits (142), Expect = 2e-07
 Identities = 103/410 (25%), Positives = 157/410 (38%), Gaps = 57/410 (13%)

Query: 207   GPEDVVAQTGSSVTFQ-CRVGGDPLPDVL--WR--RSAGGGNMPLGRVKVLDDGSLRLDN 261
             G  D+++ T  S+T    R   D   ++L  W   R AG         +   D    +  
Sbjct: 30068 GEFDIISITKDSITIHWLRPESDGGKEILGYWIEFRQAGESAWKKCNKERSKDRQFTIGG 30127

Query: 262   VILADEGEYSCEAENSVG-------AVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
             ++ A E E+   AEN  G       A+     L+V + P +         + G     TC
Sbjct: 30128 LMEATEYEFRVFAENETGLSRPRRTAMGIKTKLSVGEAPCLKEDIKDTTTKLGESGILTC 30187

Query: 315   TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
                GRP P + W   G   I     SR KY  ++  DG        TD+ +      C A
Sbjct: 30188 QIIGRPLPEIKWYRYGKELI----QSR-KYKMSS--DGRNHSLSVMTDEQEDEGLYTCRA 30240

Query: 375   VNYAGSSFVRGKLTVTSDDDRPP--PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
             VN AG     GKL + +     P  P+     +     ++   V+    I  P P I W+
Sbjct: 30241 VNEAGEIETSGKLLLQAAPQFHPGFPLKEKYYAGCGTSLRLHVVY----IGRPIPQIMWF 30296

Query: 433   FEGEALIQNHRRNVTNDGT-----LVLKDLD-KSDSGTYTCVASSRHGKYVWSGALLVDS 486
             +  + L  N   NV  + T     LV++++  K+++G Y    S++ G         VD+
Sbjct: 30297 YGKKPL--NPSENVIIENTESYTHLVIRNVQRKTNAGRYKVQLSNKFG--------TVDT 30346

Query: 487   PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRE 546
              +   I      D   LP  P   +   +  +SV +SW      G S I  Y VE   RE
Sbjct: 30347 VLRVEIQ-----DKPLLPEGPV--VVDALLKSSVIISWKPPKDDGGSMITNYIVE--KRE 30397

Query: 547   TLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
                G         W +++  V  T   V +LI    Y F V  +N +G+S
Sbjct: 30398 AKEGEQ-------WHLVSSAVSGTTCRVPNLIESSGYYFRVSAQNQYGIS 30440



 Score = 60.1 bits (139), Expect = 4e-07
 Identities = 79/323 (24%), Positives = 135/323 (41%), Gaps = 38/323 (11%)

Query: 504   PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
             PGPP K    ++   +VTLSW + ++ G S I GY VE +          P + + W+  
Sbjct: 13598 PGPPYKLEPSDIAKDAVTLSWYEPDEDGGSPITGYWVERYE---------PDHDK-WIRC 13647

Query: 564   AR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLW-EGTGVS 621
              +  +  T++ VK L     Y F V  EN  G   PS  +D + + D  +  W  G    
Sbjct: 13648 NKLPIRDTNFRVKGLPTRKKYKFRVLAENLAGPGKPSKETDQILIKDPIDPPWAPGKPTV 13707

Query: 622   NSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNI-TIEYEM 680
                   +  L     E      I+S  ++L+          G   + R  DNI ++E+ +
Sbjct: 13708 KDVAKTSAFLQWTKPEHDGGAKIESYIVELL--------KSGTDEWVRVADNIPSLEHFL 13759

Query: 681   KTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEM 740
             K ++   + S F + ++    + E            +PS+  + +   + P  PP  + +
Sbjct: 13760 KGLMEKQEYS-FRVRAVNVAGESE----------PSEPSDPVLCKERLN-PPSPPRWLLV 13807

Query: 741   FILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNL 800
                +  +  LKW+ PE   ++G     N +V   DV   K   A++TTV +     +T L
Sbjct: 13808 VSSSRNSAELKWTAPE---RDGGSPITNYIVEKRDV-RRKGWQAVDTTVKE-LKYTVTPL 13862

Query: 801   TSGVSYSVQIAAETIIGLGPFSQ 823
               G  Y  ++AAE  +G   F +
Sbjct: 13863 NEGSLYVFRVAAENAVGPSEFCE 13885



 Score = 59.7 bits (138), Expect = 5e-07
 Identities = 94/405 (23%), Positives = 156/405 (38%), Gaps = 36/405 (8%)

Query: 99   ATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH 158
            A L V     EF    +  +  +    V EC      P   V W K+GQ L      ++ 
Sbjct: 2822 AKLFVEARVIEFTKHIKDIKVTEKKKAVFEC--ELSEPNVQVTWMKDGQELELSERYKVS 2879

Query: 159  LVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP--EDVVAQT 215
                 + L+IQ  R +DAG Y  +A ++        A L +  K   I+ P  +++    
Sbjct: 2880 TERHVHRLMIQTVRMSDAGEYSVVAGSSVSK-----ANLTVEGKDVRISEPAEKEITVLE 2934

Query: 216  GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR----VKVLDDGSLRLDNVILADEGEYS 271
                TF+  V  D + +  W R+       + +      +     L +     +D GEY+
Sbjct: 2935 KQRSTFEFEVNEDDI-EGRWLRNGVEIQFSVDQRFNYAIIRKIHRLTITETYRSDAGEYT 2993

Query: 272  CEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGN 331
              A  +   V+   ++ + +PP I      ++VE+G  ARF+   TG P+P + W    N
Sbjct: 2994 FIAGKNRSIVTL--HVNIPEPPQIIRHMQPLSVEAGKPARFSVEVTGIPQPQVSW--YKN 3049

Query: 332  RTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL---- 387
               +  G    K       +  T+L I    ++ ++    C A N  G +     L    
Sbjct: 3050 SQALSSGF---KCKFLREGNEHTLLLIEVFPEDAAQYN--CEAKNDYGVATSSASLNVEV 3104

Query: 388  --TVTSDDDRP--PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR 443
               V+ D   P  PP++     N +      A F C  +   +  I WY + + + Q+  
Sbjct: 3105 PEVVSPDTGAPLSPPVVLTPIQNTSANEGQSARFQC-RVSGEDLTITWYCKDKEIKQSDI 3163

Query: 444  RNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485
              V+    +  L +  +   D G YTCVA +  G    S  L VD
Sbjct: 3164 FRVSQFDENCQLEITRVYPEDEGEYTCVARNSAGMVSCSALLKVD 3208



 Score = 59.7 bits (138), Expect = 5e-07
 Identities = 55/199 (27%), Positives = 84/199 (42%), Gaps = 16/199 (8%)

Query: 5    YVTSGEAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
            ++T+ + P   + PL  VTV   +  TL+C   GSP   I+W K    + S  +  I   
Sbjct: 7500 HITAQKVPPSFDLPLKPVTVNEGETLTLSCHVRGSPPLKIQWMKDRRELSSSANTKITFV 7559

Query: 64   GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE--------FRLE-P 114
             G   L  T     +D+G Y C+ATN  G      A    A    +        F +E P
Sbjct: 7560 DGTATLEMTRVS-KTDSGDYLCKATNEAGNKPGAPAPAQAAPSPPQEVKKFDNLFFIEVP 7618

Query: 115  ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG---NLVIQDAR 171
            +S    +  T         G P PNV W K     +  G  R+ +   G    + I++  
Sbjct: 7619 KSVHIVEKGTATF-IAKVGGDPIPNVKWMKGKWRQMTHG-GRISIEQKGQEAKMEIKEVT 7676

Query: 172  QTDAGRYQCIARNAAGTRE 190
            ++D+G+Y+C+A N  G  E
Sbjct: 7677 KSDSGQYRCVASNKHGEIE 7695



 Score = 59.7 bits (138), Expect = 5e-07
 Identities = 83/337 (24%), Positives = 137/337 (40%), Gaps = 39/337 (11%)

Query: 274   AENSVGAVS----ASGYLTV---YDPPSINLSPNS---VNVESGNVARFTCTATGRPEPT 323
             A+N+ G  S    ++G +TV    DPP I +       V +++G + R     +GRP P 
Sbjct: 25396 AKNAAGLFSEPSESTGPVTVKDDVDPPRITIEDKLRQLVVIKAGEILRIDAEISGRPIPV 25455

Query: 324   MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383
             + W+ +G         ++ ++  ++     T++ + D  + DS    V +  N AG+  +
Sbjct: 25456 ISWAKDGKEI-----EAKARFEISSTLTSTTLI-VRDAIRRDS-GQYVLTLQNVAGTRSL 25508

Query: 384   RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR 443
                  V    DRP      GPS+  L I  +    CT    P P      E +  I   R
Sbjct: 25509 AVNCKVL---DRP------GPSSGPLDITGLTAEKCTLTWGP-PQENGGAEIQHYIVEKR 25558

Query: 444   RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSL 503
                    TLV  D+ K+ +   T +       +   G     +         +A D  ++
Sbjct: 25559 ETSRLAWTLVYADM-KATTCKVTKLLKGNEYIFRVRGVNKYGTGEALESDPAKAMDPFTV 25617

Query: 504   PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
             P  PT     +VT  ++T+ W +    G SSI GY +E   RE        ++   WV +
Sbjct: 25618 PAAPTDVEVTSVTSEAMTICWERPISDGGSSISGYVIE--KRE--------KSGLRWVRV 25667

Query: 564   ARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
              ++ V+       +L  G  Y + V  EN+ GLS PS
Sbjct: 25668 NKKPVYDLRVKASNLREGCEYEYRVFAENAAGLSAPS 25704



 Score = 58.8 bits (136), Expect = 8e-07
 Identities = 49/193 (25%), Positives = 86/193 (44%), Gaps = 7/193 (3%)

Query: 7     TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGG 65
             T+  AP+  ++  D+ V     AT   +  G P P ++WYK G  +++D  +  +    G
Sbjct: 30556 TALRAPFFKDELRDMCVKYKANATFVTKVVGHPKPVVKWYKNGKEILADGAKIKVQEFKG 30615

Query: 66    LFFLRATHGRVHSDAGVYWCEATNSYGT-ARSRNATLHV-AVLREEFRLEPESKQSAQGD 123
              +F         +DA  Y   ATN  G+ + S N  + V A +     L+      A   
Sbjct: 30616 GYFQLVISNADENDAAAYQIRATNQLGSISTSMNLDVEVPAKIYLPLHLQGMGAVHAIRG 30675

Query: 124   TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLV-IQDARQTDAGRYQC 180
              VV   +P  G P+P V W+K GQ ++ +      ++     +LV ++  ++ D+G Y  
Sbjct: 30676 EVVTIKIPISGKPDPVVTWQK-GQEIINNTAYHQVIITRSFTSLVFLKGVQRKDSGYYII 30734

Query: 181   IARNAAGTRESAI 193
              A+N  G  +  +
Sbjct: 30735 CAKNRFGMDKQTV 30747



 Score = 58.4 bits (135), Expect = 1e-06
 Identities = 109/457 (23%), Positives = 177/457 (38%), Gaps = 60/457 (13%)

Query: 374   AVNYAGSSFVRGKLT--VTSDDD-RPPPIITNGPSNQTLPIKSMAVFPCTA--ICTPEPI 428
             A N AG S V    T  +T+ D+  PP I  +   +Q + + +   F   A  +  P P 
Sbjct: 22151 ARNAAGVSSVPSDSTGAITAKDEVDPPQIDLDAKYSQNVVVNAGESFRIDAGILGKPIPS 22210

Query: 429   IAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485
             + W   GE L    R  + N     TL +K+  + D G YT +  +  G+     +++++
Sbjct: 22211 VHWIKSGEELTNTARLEIKNTDFTTTLSVKEAIRVDGGQYTLLLKNVGGEK----SVIIN 22266

Query: 486   SPINPNIHFFRAADVSSLPGPPTKPIT-HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFS 544
                           V   PGPP  PI+ + VT     +SW      G + +  Y VE   
Sbjct: 22267 ------------VKVLDRPGPPDGPISIYGVTSEKCCISWKTPLHDGGAEVSHYIVE--R 22312

Query: 545   RETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDS 604
             RET        +   W V+  +V   +  +  L+PG  Y+F V   N +G+  P   SD 
Sbjct: 22313 RET--------SRLVWTVVELKVQTLNLKITKLLPGNEYIFRVIPVNKYGIGEPLE-SDP 22363

Query: 605   VTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGL 664
             V     +N        SN     +NI  D +V   E    D  +            + G 
Sbjct: 22364 VIA---ANPFVTPEAPSNVEV--SNITKDSMVITWERPTNDGGSA-----------ITGY 22407

Query: 665   FIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRV- 723
              +  R  + +      K ++       F +T L +   YEF +        GKPS   V 
Sbjct: 22408 IVEKRDKEGVRWTRCNKRVVSE---LRFRVTGLLEMRSYEFRVSAENAAGVGKPSPPTVY 22464

Query: 724   AQTLDDV-PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSM 782
              +  D V   GPP N ++  ++  +V L WS P   + +G     + +V   +V +++ +
Sbjct: 22465 FKAADPVFKPGPPNNPKVAYVSRASVVLHWSKP---IYDGGCEIQSYIVEACEVTSDEWV 22521

Query: 783   VAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819
             +    +    T      L     Y  +I A   IG+G
Sbjct: 22522 MCTPPSGITETRFEAKKLLEKHEYKFRICAVNKIGVG 22558



 Score = 58.4 bits (135), Expect = 1e-06
 Identities = 82/316 (25%), Positives = 123/316 (38%), Gaps = 47/316 (14%)

Query: 304   VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
             V  G V R +    G+P PT  W+ EG R I    M        A  +  T L I +  +
Sbjct: 29781 VRQGGVIRLSVPIKGKPLPTCKWTKEG-RDISHRAM-------IATSEERTELVIKEAHR 29832

Query: 364   NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP-PIITNGPSNQTLPIK--------SM 414
             +D+  T      N  G   V  K+ V    D P  P+  +    +++ +           
Sbjct: 29833 DDT-GTYDLVLENKCGRKAVYIKVKVIGRPDPPEGPLEFDDIQARSVRVSWRPPSDDGGS 29891

Query: 415   AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
              +F         P  AWY     ++         D +LV+K L ++    +   A ++ G
Sbjct: 29892 DIFGYIVERREVPKAAWYTVDSRVV---------DTSLVVKGLKENVEYHFKITAENQFG 29942

Query: 475   KYVWSGALLVDSPINPNIHFFRAADVSSLPGPPT-KPITHNVTDTSVTLSWSQNNKIGSS 533
                 S +L  D  + P             P PP+  P   +VT T++ LSWS+    G S
Sbjct: 29943 I---SKSLKSDESVTPKTPLCP-------PEPPSFPPEIMDVTKTTIGLSWSRPKDDGGS 29992

Query: 534   SILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSH 593
              + GY VE   R  +S     R+++        +  T Y +  LIP   Y F V  +N  
Sbjct: 29993 RVTGYYVE---RREISTEKWVRHNK------THITTTMYTLTGLIPDAEYQFRVVAQNDI 30043

Query: 594   GLSGPSPVSDSVTVGD 609
             G S P PVS+SV   D
Sbjct: 30044 GQSEPGPVSESVVCKD 30059



 Score = 58.4 bits (135), Expect = 1e-06
 Identities = 59/197 (29%), Positives = 85/197 (43%), Gaps = 15/197 (7%)

Query: 134   GSPEPNVYWKKNGQTLLFDGDS-RMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGTRE 190
             G P+P V W KNG+ +L DG   ++    GG   LVI +A + DA  YQ  A N  G+  
Sbjct: 30586 GHPKPVVKWYKNGKEILADGAKIKVQEFKGGYFQLVISNADENDAAAYQIRATNQLGSIS 30645

Query: 191   SAI-ATLKIHIKPYL---ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
             +++   +++  K YL   + G   V A  G  VT +  + G P P V W++     N   
Sbjct: 30646 TSMNLDVEVPAKIYLPLHLQGMGAVHAIRGEVVTIKIPISGKPDPVVTWQKGQEIINNTA 30705

Query: 247   GRVKVLD---DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
                 ++       + L  V   D G Y   A+N  G    +  L V D P     P  V 
Sbjct: 30706 YHQVIITRSFTSLVFLKGVQRKDSGYYIICAKNRFGMDKQTVELDVADVPD---PPKDVK 30762

Query: 304   VESGNVARFTCTATGRP 320
             V   ++ R T T T  P
Sbjct: 30763 V--SDIGRDTLTLTWSP 30777



 Score = 58.0 bits (134), Expect = 1e-06
 Identities = 35/136 (25%), Positives = 72/136 (52%), Gaps = 7/136 (5%)

Query: 110  FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVI 167
            F  +P S + ++G T   + L   G P P+ +W  +GQ ++ D   ++ + + G  ++++
Sbjct: 1231 FVQKPSSFRCSEGQTARFD-LKVVGRPMPDTFWFHSGQQVVNDYTHKIVVKEDGTQSMIV 1289

Query: 168  QDARQTDAGRYQCIARNAAG-TRESAIATLKIH---IKPYLITGPEDVVAQTGSSVTFQC 223
              A   D+G +  +A+N AG T  S   T++     ++P  I   +++  + GS V    
Sbjct: 1290 VPAMPQDSGEWTVVAQNRAGKTTVSMTLTVEAKENLVRPQFIEKLKNISVKEGSLVELAV 1349

Query: 224  RVGGDPLPDVLWRRSA 239
            +  G+PLPD++W +++
Sbjct: 1350 KAIGNPLPDIVWLKNS 1365



 Score = 57.6 bits (133), Expect = 2e-06
 Identities = 81/322 (25%), Positives = 120/322 (37%), Gaps = 39/322 (12%)

Query: 292   PPSINLSPNS---VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
             PP I L  +    VN+ + +  R      GRP P + WS E    +      R     T 
Sbjct: 21493 PPEIELDSDLRKVVNIRACSTLRLFVPVKGRPAPEIRWSREKGEPL-----DRASIEITP 21547

Query: 349   VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408
              F   T L I + D+ D    ++ +  N +G+      + V      P          Q 
Sbjct: 21548 SF---TTLLIENVDRFDGGKYML-TVENSSGTKTAFINVRVLDTPGAP----------QN 21593

Query: 409   LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468
             L IK +     + I  P P+I    +G + I+++              ++ S   T   +
Sbjct: 21594 LTIKEITKDSVSLIWDP-PVI----DGGSRIRHYIVEKRESTRKAYSIVNASCPKTSWRI 21648

Query: 469   ASSRHGKYVWSGALLVDS-PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527
                + G   +   L  +   +   +    A  +S  P PP K     VT  SVTLSW + 
Sbjct: 21649 GDLQEGNLYFFRILAENEYGVGLPVETMEAIKISERPLPPGKVTLKEVTSNSVTLSWEKP 21708

Query: 528   NKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIV 587
             +  G S I GY VE      + G    +NS  W  +   V  T  VV  L  G  Y F +
Sbjct: 21709 DHDGGSRITGYIVE------MQG----KNSDKWTQV-MTVKVTEAVVVGLTQGEEYSFRI 21757

Query: 588   RTENSHGLSGPSPVSDSVTVGD 609
                N  G+S P P+S  V   D
Sbjct: 21758 SATNEKGISDPRPLSVPVIAKD 21779



 Score = 57.2 bits (132), Expect = 3e-06
 Identities = 50/182 (27%), Positives = 79/182 (43%), Gaps = 25/182 (13%)

Query: 425   PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
             P P++ W  E + L Q  R N+ N  +  + ++++        +     G+Y  +G  ++
Sbjct: 20729 PRPLVVWKKEDQELKQTQRINIENTASSTILNINE--------IKRKDGGQYSMTGKNIL 20780

Query: 485   DSPINPNIHFFRAADVSSLPGPPTKPIT-HNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543
              + +  NI       V  +PGPPT PI    V+   V +SW      G   I  Y VE+ 
Sbjct: 20781 GT-VTENI----TVQVHDIPGPPTGPIKLDEVSCDYVLISWEAPENDGGVPINNYIVEM- 20834

Query: 544   SRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
              RET            W+ +A  V +T +    L  GI Y F V+ +N +G+ GP   S 
Sbjct: 20835 -RET--------TGTSWMELAATVIRTTFKAARLTTGIEYQFRVKAQNRYGV-GPYITSG 20884

Query: 604   SV 605
              V
Sbjct: 20885 PV 20886



 Score = 56.8 bits (131), Expect = 3e-06
 Identities = 84/332 (25%), Positives = 132/332 (39%), Gaps = 57/332 (17%)

Query: 293   PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
             PS  L+ N+ +V+SG   +      GRP P + W  +G         +R    +TA    
Sbjct: 23947 PSFKLTFNTYSVQSGEDLKVEIPFKGRPTPKIGWMKDGQ---ALKETTRLNVSSTAT--- 24000

Query: 353   VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
              TVL I + ++ DS    + +A N  G        TVT   +    II + P   T P+K
Sbjct: 24001 STVLKIKEANREDSGKYTI-TATNNIG--------TVT---EEVAIIILDKPGPPTGPVK 24048

Query: 413   SMAVFPCTAICTPEPIIAWYFEGEALIQNH---RRNVTNDG-----------TLVLKDLD 458
                V     + + EP +   + G   I N+   +R+ T              T+ +  L 
Sbjct: 24049 IDEVSATYVVISWEPPV---YTGGCQINNYVVEKRDTTTTNWQTVSATIARTTIKISKLK 24105

Query: 459   KSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDT 518
                   +   A +R+GK   SG+ +  +P+  +  F       + P  P  P   +VT  
Sbjct: 24106 TGSEYQFRVFAENRYGK---SGS-IDSTPVVVSYPF-------TEPAAPGAPFVSSVTKD 24154

Query: 519   SVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSL 577
              +T+ W   +  G S I+GY +E             +NS  W  + +  +  T      L
Sbjct: 24155 HMTIEWKPPSNNGGSPIIGYHLE----------RKEKNSILWTKLNKLLITDTRLRTNGL 24204

Query: 578   IPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
               GI Y + V  EN  G+S  S VS+SV   D
Sbjct: 24205 EEGIEYEYRVFAENIAGISPSSKVSESVVARD 24236



 Score = 56.4 bits (130), Expect = 4e-06
 Identities = 60/218 (27%), Positives = 91/218 (41%), Gaps = 33/218 (15%)

Query: 388   TVTSDDD-RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-YFEGEALIQNHRR- 444
             +VT+ D+  PP        +Q L + +   F   A    +PI A  +F+G+  ++N  R 
Sbjct: 23248 SVTAKDEVEPPTYEVASEYSQILTVNAGDTFSLEASVLGKPIPAMQWFKGDVEVENSARA 23307

Query: 445   ---NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVS 501
                N      LV+KD  + D G YT   S+  G             ++ N+       V 
Sbjct: 23308 EIKNTDFKAVLVVKDAIRIDGGQYTLHLSNVAG----------SKSVSFNVR------VL 23351

Query: 502   SLPGPPTKPIT-HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGW 560
               PGPP  P+T   VT+   +LSW      G SSI  Y ++   RET        +   W
Sbjct: 23352 DRPGPPEGPLTVSGVTNEKCSLSWLPPRHDGGSSISYYVIQ--KRET--------SRLAW 23401

Query: 561   VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
              V++     T + V  L+ G  Y+F V   N +G+  P
Sbjct: 23402 TVVSGDCGATMFKVTKLLKGNEYIFRVMAVNKYGVGEP 23439



 Score = 56.0 bits (129), Expect = 6e-06
 Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 7/129 (5%)

Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA---GGGNMPLGRVKVLDDGS-LRLDNVIL 264
           + VVA  GS+ TF+ +V G+P+P+V W R         +P  ++   D  + L +  V  
Sbjct: 13  QSVVALEGSAATFEAQVSGNPVPEVSWFRDGQVLTAAALPGAQISFSDGRAVLMIPAVTA 72

Query: 265 ADEGEYSCEAENSVGAVSASGYLTV---YDPPSINLSPNSVNVESGNVARFTCTATGRPE 321
           A  G +S  A N  G  +++  L V     PP+      S+ V  G+  R     TG P 
Sbjct: 73  AHSGRFSVRATNGAGQATSTAELLVTAETAPPNFIQRLQSLTVRQGSQVRLDVRVTGIPA 132

Query: 322 PTMFWSVEG 330
           P + +  EG
Sbjct: 133 PVVKFYREG 141



 Score = 56.0 bits (129), Expect = 6e-06
 Identities = 74/298 (24%), Positives = 120/298 (40%), Gaps = 18/298 (6%)

Query: 202  PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKV---LDDGSL 257
            P+ +  P       G SV F C++GG P P + W++S  G  +  G R +V    D G  
Sbjct: 875  PFFVKKPVVQKLVEGGSVVFVCQIGGSPKPHIYWKKS--GVPLTTGYRYRVSHNKDTGEC 932

Query: 258  RLD-NVILADE-GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315
            +L+ ++  AD+ GEY+  A+N  G  SAS  L   +     +    V   +   A     
Sbjct: 933  KLEISMTFADDAGEYTIFAKNQHGETSASTSLLEEEEFEAYMKKQDVTYVTEVTAMVQEP 992

Query: 316  ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN-TIVCSA 374
                  P +    E  + +I   M++ +      F   T   I+  ++   +   I    
Sbjct: 993  KVADVPPVVVSEYE--KELIQRRMAQ-QTQMMQTFISETEFQISAIERKIIQEIEIRILK 1049

Query: 375  VNYAGSSFVRG-KLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWY 432
            + Y       G ++ +   +        + P      ++ M V F C     P P IAWY
Sbjct: 1050 ITYQELVIEDGEEMVINVAEHEAVASSFSTPVKSYRILEGMGVTFHCKMGGKPLPKIAWY 1109

Query: 433  FEGEALIQ--NHRRNVTNDG--TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
             +G+ +     ++  V  DG  +L L  +   D G YT  AS+  G  V SG L V+S
Sbjct: 1110 KDGKRIKHGGRYQMEVLQDGRASLRLPVVLPEDEGIYTAFASNMKGNAVSSGKLYVES 1167



 Score = 55.6 bits (128), Expect = 8e-06
 Identities = 33/112 (29%), Positives = 53/112 (47%), Gaps = 2/112 (1%)

Query: 497   AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556
             A D    PGPP      + T TS+TLSW++    G + ++GY VE+  +  + G      
Sbjct: 18155 AKDPIEPPGPPGSLKVVDSTKTSITLSWAKPVYDGGAPVIGYLVEMRDKVEMEGEQVRDP 18214

Query: 557   SRGW--VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVT 606
               GW     + ++  T Y + +L     Y F V  +N  G+  P+ V D+V+
Sbjct: 18215 EEGWKKCNTSGQLVLTEYTISNLDERQEYEFRVSAQNQVGMGRPANVKDAVS 18266



 Score = 55.6 bits (128), Expect = 8e-06
 Identities = 47/185 (25%), Positives = 79/185 (42%), Gaps = 30/185 (16%)

Query: 425   PEPIIAWYFEGEALIQNHR---RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
             P+PII W  +   L ++ +   R   N  +L++++  K ++G YT V  ++  K  +   
Sbjct: 27226 PKPIIQWMKDDVILKESEQVRFRQTENKASLIVRNARKENAGKYTLVLDNKLVKNFFDIK 27285

Query: 482   LLVDSPINPNIHFFRAADVSSLPGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSILGYQV 540
             ++   P                P  P  PI  + +   S+ +SW    + G   I  Y V
Sbjct: 27286 VITLGP----------------PSQPIGPIRFDEIKAQSIIISWDVPQEDGGGEITCYSV 27329

Query: 541   EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600
             E   RET        +   W ++   V +T + + +L+ G  Y F VR EN +G+S P  
Sbjct: 27330 E--KRET--------SQAAWKIVCSSVVRTTFKIPNLVKGTEYQFRVRAENKYGVSDPLT 27379

Query: 601   VSDSV 605
               D V
Sbjct: 27380 SPDVV 27384



 Score = 55.2 bits (127), Expect = 1e-05
 Identities = 60/227 (26%), Positives = 89/227 (39%), Gaps = 20/227 (8%)

Query: 182  ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
            AR    T ES +  L    KP  +  P       G +  F  +V G P+PD  W  S   
Sbjct: 1212 ARRLDDTDESQLERL---YKPVFVQKPSSFRCSEGQTARFDLKVVGRPMPDTFWFHSGQQ 1268

Query: 242  -GNMPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP-----P 293
              N    ++ V +DG  S+ +   +  D GE++  A+N  G  + S  LTV        P
Sbjct: 1269 VVNDYTHKIVVKEDGTQSMIVVPAMPQDSGEWTVVAQNRAGKTTVSMTLTVEAKENLVRP 1328

Query: 294  SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV--FD 351
                   +++V+ G++      A G P P + W    N  II P     KY    +    
Sbjct: 1329 QFIEKLKNISVKEGSLVELAVKAIGNPLPDIVWL--KNSDIISP----HKYPHIKIEGAK 1382

Query: 352  GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398
            G     I  T  +DS      +A+N AG    R ++ V  +   P P
Sbjct: 1383 GQAHFQIPQTSGSDSA-WYTATAINKAGRDTTRCRVNVEVEYTEPVP 1428



 Score = 55.2 bits (127), Expect = 1e-05
 Identities = 75/331 (22%), Positives = 137/331 (41%), Gaps = 33/331 (9%)

Query: 11    APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
             A   I +P +  V   + A   C      +  ++W KG   + SD    I+  G    L 
Sbjct: 12267 AAEFIARPQNQEVVEGEKAQFVCSVS-KDTYEVKWLKGNTELQSDDKYEIISEGKKRVLI 12325

Query: 71    ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVLEC 129
               +  +  + G          GT R   A+  + VL +   + P +  ++ +G   VL C
Sbjct: 12326 VKNCELKDEGGFVVL-----IGTTR---ASADLTVLEKLRIITPLKDTKANEGQETVLNC 12377

Query: 130   LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIARNAA 186
                  +      W KN +TL F+  S+  +V   N   L I+D +++D   Y     N  
Sbjct: 12378 --EVNTEGAKAKWLKNNETL-FES-SKFIMVQKDNVFSLRIKDTQKSDEANYTITLTNQR 12433

Query: 187   GTRESAIATLKIHIKPY-LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
               +  + A + +H +   ++  PEDV  Q   +++F C+V    +  V W ++  G  + 
Sbjct: 12434 AEQAKSSANITVHEEDLRIVVPPEDVDTQEKKAISFTCKVNRQNV-TVQWMKA--GQEIT 12490

Query: 246   LGRVKVL-----DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS-INLSP 299
             L + ++L     +  +L + +  LADEGEY+  A    G   A+  L + + P+      
Sbjct: 12491 LSK-RILYRVDKEKHTLTIKDCSLADEGEYTVIA----GPDKATAELIISEAPTDFTAQL 12545

Query: 300   NSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
             +   +     A F+C  T + +  + W  +G
Sbjct: 12546 SDQTITEFEDAEFSCELT-KEKADIKWYRDG 12575



 Score = 54.4 bits (125), Expect = 2e-05
 Identities = 82/325 (25%), Positives = 127/325 (39%), Gaps = 39/325 (12%)

Query: 504   PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
             PGPP      +V    V L W      G S I  Y V+   RET   N        W  +
Sbjct: 19058 PGPPASVRISHVFADRVKLRWEPPLADGGSEITNYIVD--KRETSRAN--------WAQV 19107

Query: 564   ARRVHQ--THYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVS 621
                ++   T   V+ LI G  Y F +  EN +G+  P  V+ SV     + + ++  G  
Sbjct: 19108 TANINGQITDCSVEKLIEGHEYEFRISAENKYGVGDPI-VTSSVM----AKNPFDVPGPC 19162

Query: 622   NSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNIT-IEYEM 680
                    N+  DH+    +A   D K   L           G  +  R   ++  ++   
Sbjct: 19163 EPPVI-TNVTRDHMTVTWKAPANDGKATIL-----------GYMVEKRETQDLNWVKVNR 19210

Query: 681   KTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN-SRVAQTLDDV-PDGPPINI 738
             + ++     +G     L + T+YEF +I   K   GKPS+ S     LD V P GPP   
Sbjct: 19211 RPVIDRTIKAG----GLTEGTEYEFRVIALNKAGLGKPSDPSSGVLALDPVYPPGPPAFP 19266

Query: 739   EMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMT 798
             ++     +++ L W+ P       I+ GY  +V +    A + M        QAT   +T
Sbjct: 19267 KVVDSTHSSISLSWTKPAYDGGCEIL-GY--LVEFKRADAEEWMKCNVPKNLQATKFNVT 19323

Query: 799   NLTSGVSYSVQIAAETIIGLGPFSQ 823
              L     Y  +++A   IG G  S+
Sbjct: 19324 GLIDNTEYQFRVSAVNKIGFGEPSE 19348



 Score = 53.6 bits (123), Expect = 3e-05
 Identities = 61/208 (29%), Positives = 81/208 (38%), Gaps = 20/208 (9%)

Query: 5    YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
            +V   E P II     ++V   +PA  +    G P P + WYK    + S      L  G
Sbjct: 3006 HVNIPEPPQIIRHMQPLSVEAGKPARFSVEVTGIPQPQVSWYKNSQALSSGFKCKFLREG 3065

Query: 65   GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV-----------LREEFRLE 113
                L         DA  Y CEA N YG A S +A+L+V V           L     L 
Sbjct: 3066 NEHTLLLIE-VFPEDAAQYNCEAKNDYGVATS-SASLNVEVPEVVSPDTGAPLSPPVVLT 3123

Query: 114  PESKQSA-QGDTVVLECLPPRGSPEP-NVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDA 170
            P    SA +G +   +C   R S E   + W    + +      R+   D    L I   
Sbjct: 3124 PIQNTSANEGQSARFQC---RVSGEDLTITWYCKDKEIKQSDIFRVSQFDENCQLEITRV 3180

Query: 171  RQTDAGRYQCIARNAAGTRESAIATLKI 198
               D G Y C+ARN+AG   S  A LK+
Sbjct: 3181 YPEDEGEYTCVARNSAG-MVSCSALLKV 3207



 Score = 53.6 bits (123), Expect = 3e-05
 Identities = 75/319 (23%), Positives = 125/319 (39%), Gaps = 36/319 (11%)

Query: 304   VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV------FDGVTVLT 357
             V +G   +   T TGRP P + W  +G          +D+ H   V       D  +V+T
Sbjct: 15595 VRAGTPFKIPATITGRPAPKVTWEFDGKAKT----EKKDRLHILPVDSQVESTDTTSVVT 15650

Query: 358   INDTDKNDS-RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416
             +  + ++ S R TI  +A N +G   V  ++ V      P  +     +  T+ +    +
Sbjct: 15651 VPVSLRSHSGRYTI--TAKNKSGQKHVNVRVNVLDVPGAPKELKVTDVTRTTMRL----I 15704

Query: 417   FPCTAICTPEPIIAWYFEGEALIQNHRRNVTN----DGTLVLKDLDKSDSGTYTCVASSR 472
             +        E I +++ E +A +      V N        V+ +L +     +   A +R
Sbjct: 15705 WKLPDNDGGERIKSYFIEKKA-VNGKAWTVANATCASMAFVVSNLLEGQDYFFRVRAENR 15763

Query: 473   HGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGS 532
              G            P        RA D    P PPTK   + VT  +VTL+W      G 
Sbjct: 15764 LGF----------GPFTETTEPVRARDPIYPPDPPTKVKINLVTKNTVTLTWVPPKNDGG 15813

Query: 533   SSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENS 592
             + +  Y +E  S +T SG   P+         R V +T ++++ L  G  Y F V+  N 
Sbjct: 15814 APVKHYIIERLSWDT-SG---PQKETWKQCNKRDVEETTFIIEDLKEGGEYEFRVKAVNE 15869

Query: 593   HGLSGPSPVSDSVTVGDDS 611
              G S PS  +  + + D +
Sbjct: 15870 AGASRPSVTAGPIVIKDQT 15888



 Score = 53.6 bits (123), Expect = 3e-05
 Identities = 81/315 (25%), Positives = 128/315 (40%), Gaps = 34/315 (10%)

Query: 506   PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565
             PP KP   +VT +SV+L WS+    G S ++GY VE    +         NS       +
Sbjct: 18861 PPGKPEIIDVTKSSVSLVWSRPKHDGGSKLIGYYVEFLKLKEDKWVRVNSNS-------Q 18913

Query: 566   RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTE 625
              V +  Y+V  L  G  Y F +  + +  +S PS  SD + +  +         V  S E
Sbjct: 18914 NVPKEEYIVPGLEEGAQYKFRIIAKTAINVSVPSEESDVIPIIAEH----VPPRVEISLE 18969

Query: 626   YRNNILTDHIVEL-IEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTIL 684
              +N I+      + +EA        K++W+       +G      PL  +    +M   +
Sbjct: 18970 MKNLIVVKAGANVCLEAEVYGKPMPKVVWK------KDG-----APL-KLAEGMKMTQKV 19017

Query: 685   HSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILN 744
             H   +  F +T  RK +    + I        K +N ++ + LD    GPP ++ +  + 
Sbjct: 19018 HHLSLELFSVT--RKESGE--YTITAENPSGSKSANIKL-KVLD--KPGPPASVRISHVF 19070

Query: 745   TTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGV 804
                V L+W PP L      IT Y +V       AN + V  N    Q T   +  L  G 
Sbjct: 19071 ADRVKLRWEPP-LADGGSEITNY-IVDKRETSRANWAQVTANIN-GQITDCSVEKLIEGH 19127

Query: 805   SYSVQIAAETIIGLG 819
              Y  +I+AE   G+G
Sbjct: 19128 EYEFRISAENKYGVG 19142



 Score = 53.6 bits (123), Expect = 3e-05
 Identities = 108/447 (24%), Positives = 177/447 (39%), Gaps = 58/447 (12%)

Query: 178   YQCIARNAAGTRE-SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC----RVGGDPLPD 232
             ++  A+N AG    S  +  K+ I P    G  + +  T  SVT Q     R GG  +  
Sbjct: 27464 FRVYAQNNAGMSPVSEQSKHKLAISPVDPPGTPNCIDVTRDSVTLQWEPPKRDGGSRIVA 27523

Query: 233   VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVS----ASGYLT 288
                 R  G           + +    +  +   D  E+   A N+VG VS    +SGY+ 
Sbjct: 27524 YSVERRQGRARWLRCNFIDVSECQFTVTGLAAGDRFEFRVIARNAVGTVSPPSQSSGYIM 27583

Query: 289   VYDP---PSINL-SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
               D    P I   +  S+ +++G   + +C+ +GRP P + W  +G        + +   
Sbjct: 27584 TKDESVIPQIEFEAEKSLTIKAGENIKLSCSISGRPVPQVTWYKDGKE------VDKMLV 27637

Query: 345   HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404
               T V  G + L I D D+N  R      A N +G++ V   + V   D   PP    GP
Sbjct: 27638 DITTVI-GSSSLFIRDADRN-HRGIYTVEAKNSSGTTKV--DVLVRVQDTPGPP---EGP 27690

Query: 405   SNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH--RRNVTNDGTLVLKDLDKSDS 462
                 L   +++    T   +P        +G A I N+   +  T+  +  L    K ++
Sbjct: 27691 ----LRFTNISAEKATLWWSPPE-----NDGCAAISNYVIEKRETSRISWALV-TSKCEA 27740

Query: 463   GTYTCVASSRHGKYVWSGALL----VDSPINPN-IHFFRAADVSSLPGPPTKPITHNVTD 517
              ++      +  +Y +  + +    V  P+  + I       V   PG P    TH VT 
Sbjct: 27741 CSFNATKLIKGNEYQFRVSAVNKFGVGKPLESDPIIAQMQYTVPDAPGTP--DCTH-VTG 27797

Query: 518   TSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIA--RRVHQTHYVVK 575
              S+TL W++    G + I  Y +E   RE        + S  WV ++  R + +  + V 
Sbjct: 27798 NSITLCWTRPRHDGGNEIKQYILE--RRE--------KKSLRWVKVSAKRPITELRHRVT 27847

Query: 576   SLIPGITYMFIVRTENSHGLSGPSPVS 602
             +L  G  Y F V  EN  G+   S +S
Sbjct: 27848 NLTEGNEYEFRVMAENGAGIGPASGIS 27874



 Score = 53.6 bits (123), Expect = 3e-05
 Identities = 55/247 (22%), Positives = 91/247 (36%), Gaps = 31/247 (12%)

Query: 389   VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN--HRRNV 446
             +T D+   P I      + T+         C+    P P + WY +G+ + +       V
Sbjct: 27583 MTKDESVIPQIEFEAEKSLTIKAGENIKLSCSISGRPVPQVTWYKDGKEVDKMLVDITTV 27642

Query: 447   TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGP 506
                 +L ++D D++  G YT  A +       SG   VD  +           V   PGP
Sbjct: 27643 IGSSSLFIRDADRNHRGIYTVEAKNS------SGTTKVDVLVR----------VQDTPGP 27686

Query: 507   PTKPITH-NVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565
             P  P+   N++    TL WS     G ++I  Y +E   RET        +   W ++  
Sbjct: 27687 PEGPLRFTNISAEKATLWWSPPENDGCAAISNYVIE--KRET--------SRISWALVTS 27736

Query: 566   RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTE 625
             +     +    LI G  Y F V   N  G+    P+     +     ++ +  G  + T 
Sbjct: 27737 KCEACSFNATKLIKGNEYQFRVSAVNKFGVG--KPLESDPIIAQMQYTVPDAPGTPDCTH 27794

Query: 626   YRNNILT 632
                N +T
Sbjct: 27795 VTGNSIT 27801



 Score = 52.8 bits (121), Expect = 5e-05
 Identities = 92/397 (23%), Positives = 159/397 (40%), Gaps = 55/397 (13%)

Query: 425   PEPIIAWYFEGEALIQNHRRN--VTNDGTLV-LKDLDKSDSGTYTCVASSRHGKYVWSGA 481
             P P ++   +G+ L    R N  VT D  ++ L++   SD+G Y   AS+ +G       
Sbjct: 26139 PLPKVSLSKDGQVLKSTMRFNFDVTTDSLIIYLRESVASDAGRYDITASNSNGT------ 26192

Query: 482   LLVDSPINPNIHFFRAADVSSLPGPPTKPITH-NVTDTSVTLSWSQNNKIGSSSILGYQV 540
                 S +N          V   PGP   P+   ++T+ SV+L W      G S I  Y V
Sbjct: 26193 --TKSFVN--------VVVLDRPGPAVGPVEMCDITEDSVSLKWLPPAYDGGSPITNYIV 26242

Query: 541   EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600
                 RET + N        W+ ++  V +    +  L  G+ Y F ++ EN  G+S    
Sbjct: 26243 --LKRETTTAN--------WIEVSSAVARCTIKIMKLNTGVEYQFRIKAENRFGISEHID 26292

Query: 601   VSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYY 660
              S +VTV     SL     V+ S  + + +  + IV   +    D  +           +
Sbjct: 26293 -SQTVTV-----SLPYTLPVAPSQPWVSAVTKESIVVNWKEPSSDGGS-----------H 26335

Query: 661   LEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN 720
             + G  +  +  ++I  +    T++ +   + F++T++     YEF +        G  S 
Sbjct: 26336 VFGYHLQMKDRNSILWQKVNTTVIRA---THFKVTNVNAGLIYEFKVAAENAAGIGPISK 26392

Query: 721   SRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANK 780
             S       D  + PP ++ +  +   ++ L W  P        ITGY  ++   D P  +
Sbjct: 26393 SSDPVLAIDACE-PPNSVRVTDITKNSISLAWQKPSYD-GGSKITGY--LIEMKDGPKGR 26448

Query: 781   SMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817
                A N T    T   ++ LT   SY  ++ A+  +G
Sbjct: 26449 WSKA-NLTNVTDTKFTVSGLTQNESYEFRVMAKNAVG 26484



 Score = 52.4 bits (120), Expect = 7e-05
 Identities = 50/180 (27%), Positives = 74/180 (41%), Gaps = 24/180 (13%)

Query: 134  GSPEPNVYWKKNGQTLLFDGD-SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
            G P+P V W  NG+ +      + +   D  +L+I   ++   G Y C A N  G + + 
Sbjct: 3429 GFPKPKVQWFHNGKAITSSSIYTFVEERDEYSLIITKVKKDYEGEYSCTASNRFG-QTTC 3487

Query: 193  IATLKIHIK-------------------PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233
               LK+ +                    P   T  + V    GS V FQ +V G P PDV
Sbjct: 3488 KTILKVELSQLSAAEKWVEKMFKIPGQPPCFTTQIQPVQCVEGSEVKFQYKVTGTPFPDV 3547

Query: 234  LW-RRSAGGGNMPLGRVKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290
             W + ++   +     V    DGS  L + N+   D G Y+C+A N  G  S S  L V+
Sbjct: 3548 QWFKGNSQIKSSQTCSVVCNPDGSGFLIMSNIQQRDSGLYTCKAVNPFGEASCSAELIVF 3607



 Score = 52.4 bits (120), Expect = 7e-05
 Identities = 36/103 (34%), Positives = 46/103 (44%), Gaps = 9/103 (8%)

Query: 497   AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556
             A D    P PP    THN T  SVTL+W      G S I+GY +E    + + G    + 
Sbjct: 14290 AEDQKQRPDPPVDVETHNPTSESVTLTWKPPMYDGGSKIMGYILE----KMMKGEENFQR 14345

Query: 557   SRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
                ++V         Y VK L     Y F VR EN+ G+S PS
Sbjct: 14346 CNDFLVPV-----LSYTVKGLTHEKQYQFRVRAENAAGVSDPS 14383



 Score = 52.4 bits (120), Expect = 7e-05
 Identities = 77/319 (24%), Positives = 126/319 (39%), Gaps = 41/319 (12%)

Query: 504   PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV- 562
             PGPP  P   + T +S++LSW++    G   ILGY VE F R          ++  W+  
Sbjct: 19260 PGPPAFPKVVDSTHSSISLSWTKPAYDGGCEILGYLVE-FKR---------ADAEEWMKC 19309

Query: 563   -IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVS 621
              + + +  T + V  LI    Y F V   N  G   PS V +     D    +       
Sbjct: 19310 NVPKNLQATKFNVTGLIDNTEYQFRVSAVNKIGFGEPSEVPEKHLAKD----ILLAPEAE 19365

Query: 622   NSTEYRNNILTDHIVELIEATPIDSKTI-KLMWEILNFYYLEGLFIYFRPLDNITIEYEM 680
                + R  ++    V +    P+  +   K  W  +N    E   +  +     T E++ 
Sbjct: 19366 LDADLRKALVLRAGVTMRIYVPLRGRPAPKATWTKVNANLKERQGLMIK-----TTEWD- 19419

Query: 681   KTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEM 740
              T L+  D++ ++        KY   L    +   G  S + V + LD    GPP+N+ +
Sbjct: 19420 -TFLYCEDINRYDA------GKYVLTL----ENSSGTKSYTIVVKVLD--TPGPPVNLIV 19466

Query: 741   FILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNL 800
                +   V + W  P   +  G      VV   L     K+   +     + TS  +TNL
Sbjct: 19467 KETSKDHVSITWDAP--LIDGGSPVKSYVVEKRL--AERKAWTCVAPECPK-TSFRITNL 19521

Query: 801   TSGVSYSVQIAAETIIGLG 819
              +G +Y  ++ AE I G+G
Sbjct: 19522 EAGQAYCFRVLAENIYGIG 19540



 Score = 52.4 bits (120), Expect = 7e-05
 Identities = 36/101 (35%), Positives = 47/101 (46%), Gaps = 14/101 (13%)

Query: 504   PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
             PGPP KP+  NVT   +T+ W      G S I GY +E             RNS  W+ +
Sbjct: 27392 PGPPGKPVVFNVTSDGMTVQWDAPGFDGGSPITGYHLE----------KKDRNSLLWMKV 27441

Query: 564   ARRVHQ-THYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
                V     Y V  LI G+ Y F V  +N+ G+   SPVS+
Sbjct: 27442 NTSVISGREYRVIGLIEGLEYSFRVYAQNNAGM---SPVSE 27479



 Score = 52.4 bits (120), Expect = 7e-05
 Identities = 33/109 (30%), Positives = 48/109 (44%), Gaps = 11/109 (10%)

Query: 504   PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
             PG P +P   +VT  S  +SW      G + I  Y +E   RE        +    W+ +
Sbjct: 30458 PGVPQRPFVSSVTKDSCVVSWKPPTSDGGAKIKNYFLE--KRE--------KKQNKWIAV 30507

Query: 564   AR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDS 611
                 +H+T Y  K L+ G  Y F V+ EN  G S  S +S+ V    D+
Sbjct: 30508 TTGEIHETSYTAKGLLEGFEYEFRVKCENIGGESDWSEISEPVIPKSDT 30556



 Score = 52.0 bits (119), Expect = 1e-04
 Identities = 36/111 (32%), Positives = 48/111 (43%), Gaps = 4/111 (3%)

Query: 499   DVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558
             D S+LPGPP K      + T + L+W      G S I GY +E   RE   G +      
Sbjct: 15367 DPSALPGPPEKVTIAERSKTHMLLTWEPPKDSGGSMITGYWLE--KRE--KGTSYWSRVN 15422

Query: 559   GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
               +V  R +    Y V  L  G+ Y F     NS G+  PS +S+S    D
Sbjct: 15423 KILVSKRGMKGWEYQVTRLFEGVEYEFRAMACNSAGIGPPSAISESAVADD 15473



 Score = 52.0 bits (119), Expect = 1e-04
 Identities = 36/130 (27%), Positives = 59/130 (45%), Gaps = 6/130 (4%)

Query: 692   FEITSLRKYTKYEFFLIPFYKKFEGKPS-NSRVAQTLDDV-PDGPPINIEMFILNTTTVH 749
             +  T L +  +YE+ +     +  GKPS NS+    +D + P G P+N  +     T+V 
Sbjct: 29624 YRATGLIEGLEYEYRVTAINSRGTGKPSANSKPTIAMDPIEPPGIPLNPRVTDTTRTSVS 29683

Query: 750   LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQ 809
             L WSPPE +     +TGY + +  +D          NTT  +     +T++  G  Y  +
Sbjct: 29684 LAWSPPE-EEGGAAVTGYLIEMQKVD---QVEWTKCNTTPTKICEYTLTHMPQGAEYKFR 29739

Query: 810   IAAETIIGLG 819
             + A    G G
Sbjct: 29740 VMACNAGGAG 29749



 Score = 51.6 bits (118), Expect = 1e-04
 Identities = 47/173 (27%), Positives = 74/173 (42%), Gaps = 10/173 (5%)

Query: 39    PSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG--TARS 96
             P P++ W K G  +  D  +    +    +    H    SD   Y   A N +G  + ++
Sbjct: 31349 PEPSVTWLKAGHRIKPDPKKYTFTSDKGLYQLMIHNVDLSDDAEYTVVANNKFGEDSCKA 31408

Query: 97    R-NATLHVAV---LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFD 152
             R N   H      +R  F+    +    +G +V  + L   G+P P + W+KNG+ L F 
Sbjct: 31409 RLNVAPHAVAEDTMRPMFKRLLANIDCVEGQSVRFD-LRVSGTPAPTLKWEKNGKPLEFR 31467

Query: 153   GDSRM--HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY 203
                 +    VD   L I++    D+G Y+  A N AG+  S  ATLK+    Y
Sbjct: 31468 PQVEVVQEDVDYFILHIRETLIEDSGTYRVTATNTAGS-ASCQATLKVERLTY 31519



 Score = 51.2 bits (117), Expect = 2e-04
 Identities = 39/156 (25%), Positives = 63/156 (40%), Gaps = 14/156 (8%)

Query: 458   DKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSS---LPGPPTKPITHN 514
             D +DS  YT     R  KY++           PN+   +A    +   +P  P   I  N
Sbjct: 12857 DCADSTEYTVTGLQRDSKYLFRVCARNRVGSGPNVETDKAVQAKNKFDVPDAPQNVIVGN 12916

Query: 515   VTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV-VIARRVHQTHYV 573
             V     T+SW      G S I  Y +E+  R ++           W  V+  + H+   +
Sbjct: 12917 VNKFGATVSWEPPLFDGGSEITSYIIELRDRTSVV----------WAPVMVTKPHERSAI 12966

Query: 574   VKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
             +  +I    Y+F V+ EN  G+  PS  ++ V + D
Sbjct: 12967 INDVIENKEYIFRVKAENKAGIGKPSAATNPVKIMD 13002



 Score = 51.2 bits (117), Expect = 2e-04
 Identities = 135/628 (21%), Positives = 227/628 (36%), Gaps = 64/628 (10%)

Query: 21    VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA-----THGR 75
             + V +++P  +     G P P I W K  V++   T + +     +  + +       G 
Sbjct: 15178 IRVRKNEPIEMPAEVTGLPMPKIEWLKDDVVIEKPTEKLLFETKEIDRVTSHTKLSIPGV 15237

Query: 76    VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGS 135
                D G Y   A+N  GT  S + T+ V       R    S   A+   +  +     G 
Sbjct: 15238 TRLDKGTYTVTASNRLGTL-SHSVTVEVLDRPTPPRNVAVSSIKAESCNLSWDAPLDIGG 15296

Query: 136   PEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA----RQTDAGRYQ--CIARNAAGTR 189
              E   Y  +  + L  +   +   V     +I+           G Y+    A N  G  
Sbjct: 15297 SELTNYIVEM-KDLNVEDPEKAEWVQVTKSIIEKRYGVWNLVTGGNYKFRVKAENKYGIS 15355

Query: 190   ESAIATLKIHIK-PYLITGPEDVVAQTGSSVTFQC------RVGGDPLPDVLWRRSAGGG 242
             E A  T ++ IK P  + GP + V     S T         +  G  +    W      G
Sbjct: 15356 E-ACETEEVEIKDPSALPGPPEKVTIAERSKTHMLLTWEPPKDSGGSMITGYWLEKREKG 15414

Query: 243   NMPLGRV-KVL------DDGSLRLDNVILADEGEYSCEAENS--VGAVSASGYLTVYD-- 291
                  RV K+L           ++  +    E E+   A NS  +G  SA     V D  
Sbjct: 15415 TSYWSRVNKILVSKRGMKGWEYQVTRLFEGVEYEFRAMACNSAGIGPPSAISESAVADDP 15474

Query: 292   --PPSINLSPNSVNVESGNVA-RFTCTAT--GRPEPTMFWSVEGNRTIIFPGMS-RDKYH 345
               PPS+  +P   +    +V   +T  A   GRP       ++   T  +  ++  +  H
Sbjct: 15475 LTPPSMPAAPEIADKTKHSVTLAWTPPAKDGGRPIKGYIIEIQDEGTSEWARVNDAENLH 15534

Query: 346   ATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD--RPPPIITNG 403
              + VF   T+  + +  K   R  I+  AVN  G S    + +    +D    P I  + 
Sbjct: 15535 PSTVF---TIPNLPELKKYRFR--II--AVNEIGESEPSPRTSEVRIEDIKTAPKIFMDI 15587

Query: 404   PSNQTLPIKSMAVF--PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSD 461
              +++ L +++   F  P T    P P + W F+G+A  +   R         ++  D + 
Sbjct: 15588 SADELLCVRAGTPFKIPATITGRPAPKVTWEFDGKAKTEKKDRLHILPVDSQVESTDTTS 15647

Query: 462   SGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVT 521
               T      S  G+Y      +     +   H     +V  +PG P +    +VT T++ 
Sbjct: 15648 VVTVPVSLRSHSGRYT-----ITAKNKSGQKHVNVRVNVLDVPGAPKELKVTDVTRTTMR 15702

Query: 522   LSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGI 581
             L W   +  G   I  Y +E   ++ ++G       + W V         +VV +L+ G 
Sbjct: 15703 LIWKLPDNDGGERIKSYFIE---KKAVNG-------KAWTVANATCASMAFVVSNLLEGQ 15752

Query: 582   TYMFIVRTENSHGLSGPSPVSDSVTVGD 609
              Y F VR EN  G    +  ++ V   D
Sbjct: 15753 DYFFRVRAENRLGFGPFTETTEPVRARD 15780



 Score = 51.2 bits (117), Expect = 2e-04
 Identities = 75/296 (25%), Positives = 120/296 (40%), Gaps = 36/296 (12%)

Query: 259   LDNVILADEGEYSCEAENSVG------AVSASGYLTVYDPPSINLSPN---SVNVESGNV 309
             + N+    E E+   A+N VG         A     V++ P I+L  +    ++V +G  
Sbjct: 18234 ISNLDERQEYEFRVSAQNQVGMGRPANVKDAVSPKEVHEHPEIDLDASLRKGLSVRAGCP 18293

Query: 310   ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS-RN 368
              R   T  GRP P + W   G   +I  G      H   + D +T L I ++ + DS + 
Sbjct: 18294 IRLFATIRGRPAPKVTWKRIGVDNVIRRG------HVDQI-DTMTFLVIPESSREDSGKY 18346

Query: 369   TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428
             ++  S  +   + FVR K+      D P P+     ++ T     +A  P        PI
Sbjct: 18347 SLTLSNPSGEKAVFVRVKVL-----DTPGPVGGLDATDITKTSCQLAWLP-PENDGGSPI 18400

Query: 429   IAWYFEGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485
             + +  E   + +    N TND    +  + +L       +  +A +++G       L  D
Sbjct: 18401 LNYIVEKREVDRKTWTNCTNDLKKTSFKITNLTPGIEYYFRVMAVNKYGI-----GLPQD 18455

Query: 486   SPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541
             SP +     + A D  S P PP K     +T  S TL W +  + G S I GY VE
Sbjct: 18456 SPKS-----YLATDPKSEPDPPKKMDVLEITKNSATLGWLKPLRDGGSKINGYIVE 18506



 Score = 51.2 bits (117), Expect = 2e-04
 Identities = 35/106 (33%), Positives = 51/106 (48%), Gaps = 10/106 (9%)

Query: 506   PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565
             PP++P+  N+T   VTL W++    G  SI GY VE   RE  +G     N         
Sbjct: 20995 PPSQPVALNITRHEVTLQWTKPEGDGGFSITGYTVE--KRELPNGRWLKAN-------FS 21045

Query: 566   RVHQTHYVVKSLIPGITYMFIVRTENSHG-LSGPSPVSDSVTVGDD 610
              + +T++ V  L   ++Y F V   NS G +S PS  S+ +   DD
Sbjct: 21046 NILETNFTVSGLTEDVSYEFRVLARNSAGAVSKPSKPSEVIVCRDD 21091



 Score = 50.8 bits (116), Expect = 2e-04
 Identities = 76/327 (23%), Positives = 130/327 (39%), Gaps = 50/327 (15%)

Query: 499   DVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558
             D++  PGPP+ P   + T T+ T +W +    G   + GY VE          +      
Sbjct: 20304 DIAYPPGPPSNPRITDTTKTTATFNWGRPFYDGGLDVTGYIVE----------HKKEGDD 20353

Query: 559   GWV---VIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLW 615
              WV    I  R+  T +VV +L  G  Y F V   NS GL  PS V   V + D      
Sbjct: 20354 DWVQDTTIPLRI--TEFVVSNLQSGGKYHFRVSALNSEGLGEPSEVEQVVELVDRE---- 20407

Query: 616   EGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNIT 675
             E        E R  ++      +    PI  +      E++  +Y E +     PL    
Sbjct: 20408 EVPDFELDAELRKTLVVKSGASIRIFVPIKGRPAP---EVV--WYKENV-----PL---- 20453

Query: 676   IEYEMKTILHSNDVSGFEITSLRKYTKYEF-FLIPFYKKFEGKPSNSRVAQTLDDVPDGP 734
                  K   H +    + +  + + T+Y+    +   +   GK +   V   + D P GP
Sbjct: 20454 -----KGRAHIDTTESYTLVVIPECTRYDAGKYVLTLENVAGKKTGF-VNVRVVDTP-GP 20506

Query: 735   PINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWL--DVPANKSMVAINTTVHQA 792
             P+N++   +   ++ L+W  P       +I G + + N++     A +   ++ TT  Q 
Sbjct: 20507 PVNLKPREITKHSITLQWEIP-------LIDGGSKIKNYIIEKREATRKAYSVITTNWQK 20559

Query: 793   TSLIMTNLTSGVSYSVQIAAETIIGLG 819
              S  + +L     Y  +++AE  +G+G
Sbjct: 20560 CSYKIPDLEEAAEYYFRVSAENEMGIG 20586



 Score = 50.4 bits (115), Expect = 3e-04
 Identities = 38/137 (27%), Positives = 54/137 (39%), Gaps = 7/137 (5%)

Query: 196   LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
             L +   P L    +D   + G S    C++ G PLP++ W R  G   +   + K+  DG
Sbjct: 30160 LSVGEAPCLKEDIKDTTTKLGESGILTCQIIGRPLPEIKWYRY-GKELIQSRKYKMSSDG 30218

Query: 256   ---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS---PNSVNVESGNV 309
                SL +      DEG Y+C A N  G +  SG L +   P  +             G  
Sbjct: 30219 RNHSLSVMTDEQEDEGLYTCRAVNEAGEIETSGKLLLQAAPQFHPGFPLKEKYYAGCGTS 30278

Query: 310   ARFTCTATGRPEPTMFW 326
              R      GRP P + W
Sbjct: 30279 LRLHVVYIGRPIPQIMW 30295



 Score = 50.0 bits (114), Expect = 4e-04
 Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 2/92 (2%)

Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL 259
           + P LI G ++V    G SVT +C++ G P P ++W R        +      +    RL
Sbjct: 740 VPPTLIAGLKNVTVTEGESVTLECQISGHPTPAIMWFREDYRIENSIDFQITYEKSYARL 799

Query: 260 --DNVILADEGEYSCEAENSVGAVSASGYLTV 289
                   D G ++C A +  G +S S YL V
Sbjct: 800 MIREAFAEDSGRFTCTATSEAGTISTSCYLLV 831



 Score = 50.0 bits (114), Expect = 4e-04
 Identities = 48/154 (31%), Positives = 62/154 (40%), Gaps = 7/154 (4%)

Query: 8    SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGL 66
            S EAP I+E+    TVA        CR  G P P  +W+K G+L+  SD      P   +
Sbjct: 1847 SMEAPKILERIQSQTVALADEVRFRCRVIGKPDPECQWFKNGILLEKSDRVYWYWPEDHV 1906

Query: 67   FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
              L      +  D+     +A N  G A S    L  A     F    E   + + DT+V
Sbjct: 1907 CEL-VIRDVLAEDSASIMVKAINIAGEASSHAFLLVQAKQVVSFTQTLEDAYAKEKDTMV 1965

Query: 127  -LECLPPRGSPEPNVYWKKNGQTLLFDGDS-RMH 158
              EC      P   V W KN    +F GD  RMH
Sbjct: 1966 TFEC--ETNEPFVKVKWMKNNAE-IFSGDKYRMH 1996



 Score = 49.6 bits (113), Expect = 5e-04
 Identities = 48/193 (24%), Positives = 72/193 (37%), Gaps = 14/193 (7%)

Query: 289  VYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
            +Y P  +   P+S     G  ARF     GRP P  FW   G + +       D  H   
Sbjct: 1226 LYKPVFVQ-KPSSFRCSEGQTARFDLKVVGRPMPDTFWFHSGQQVV------NDYTHKIV 1278

Query: 349  V-FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407
            V  DG   + +      DS    V  A N AG + V   LTV + ++   P       N 
Sbjct: 1279 VKEDGTQSMIVVPAMPQDSGEWTVV-AQNRAGKTTVSMTLTVEAKENLVRPQFIEKLKNI 1337

Query: 408  TLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-----LVLKDLDKSDS 462
            ++   S+      AI  P P I W    + +  +   ++  +G        +     SDS
Sbjct: 1338 SVKEGSLVELAVKAIGNPLPDIVWLKNSDIISPHKYPHIKIEGAKGQAHFQIPQTSGSDS 1397

Query: 463  GTYTCVASSRHGK 475
              YT  A ++ G+
Sbjct: 1398 AWYTATAINKAGR 1410



 Score = 49.2 bits (112), Expect = 7e-04
 Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 4/106 (3%)

Query: 190   ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249
             E ++  +K  +   ++T P  ++   G S  F C + G+P P V W    G   +   R+
Sbjct: 32125 EVSVKKIKATLSAKILTKPHSLIVSEGDSARFVCDIDGEPAPTVTWMHE-GRTVVSSHRI 32183

Query: 250   KVLD---DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
              V       +L + +V  +DEG Y+   ENS G   A   L +  P
Sbjct: 32184 HVSTTQYKSTLEISSVEYSDEGNYTVVVENSEGKQEARCTLAINKP 32229



 Score = 48.8 bits (111), Expect = 9e-04
 Identities = 35/110 (31%), Positives = 46/110 (41%), Gaps = 11/110 (10%)

Query: 500   VSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRG 559
             ++  P PP K    +VT  SV+L+W +    G S I  Y VE             +  + 
Sbjct: 26006 ITEKPSPPPKLGVTDVTKESVSLAWLKPEHDGGSRITNYLVEALE----------KGQQK 26055

Query: 560   WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
             W+        TH+VV  L     Y F VR EN  GLS P  +   V V D
Sbjct: 26056 WIKCG-STKSTHFVVDGLRENAEYYFRVRAENHAGLSDPKDMVLPVLVKD 26104



 Score = 48.0 bits (109), Expect = 0.002
 Identities = 50/197 (25%), Positives = 76/197 (38%), Gaps = 14/197 (7%)

Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGN--RTIIFPGMSRDKYHATAVF 350
           P+      SV    G+ A F    +G P P + W  +G        PG         +  
Sbjct: 6   PTFTQPLQSVVALEGSAATFEAQVSGNPVPEVSWFRDGQVLTAAALPGAQ------ISFS 59

Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
           DG  VL I       S    V  A N AG +    +L VT++    PP       + T+ 
Sbjct: 60  DGRAVLMIPAVTAAHSGRFSV-RATNGAGQATSTAELLVTAET--APPNFIQRLQSLTVR 116

Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTC 467
             S           P P++ +Y EG  +  +    +  DG   +L++ +    DSGTY+ 
Sbjct: 117 QGSQVRLDVRVTGIPAPVVKFYREGAEIQSSADFQIVQDGDLYSLLIAEAFPEDSGTYSV 176

Query: 468 VASSRHGKYVWSGALLV 484
            AS+  G+   +  LLV
Sbjct: 177 SASNSSGRATSTAELLV 193



 Score = 48.0 bits (109), Expect = 0.002
 Identities = 104/491 (21%), Positives = 183/491 (37%), Gaps = 67/491 (13%)

Query: 6     VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
             V  GE PY   +  D T        L C    S S  ++W+K G   ++ +   ++ A G
Sbjct: 11713 VLEGE-PYFTTKLQDYTAVEKDEVVLMCEVSKS-SAQVKWFKDGN-EITPSKNVLIKADG 11769

Query: 66    LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
                +         + G Y C+  +    A+       + ++R  + +E    ++A+ +T 
Sbjct: 11770 KKRILTVKKAEKGNIGEYVCDCGSDKTAAKLNIEERDIKIVRPLYSVEVTETETARFETE 11829

Query: 126   VLECLPPRGSPEPNVYWKKNGQTLL-----------FDGDSRM---HLVDGGN---LVIQ 168
             + E        + + +WK  G  L            +   + M    + + G    L++ 
Sbjct: 11830 ISE-------EDVHGHWKLKGDALHQSPVISFTPKHYFSITMMKDCEIKEEGTKHMLILY 11882

Query: 169   DARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228
             + R   AG     A NA    +  +    I     L+   +DV    G + TF C +  +
Sbjct: 11883 NVRMDMAGAVDFSAANAKSKAQLRVKARVIG----LLRPLKDVTVTAGETATFDCELSYE 11938

Query: 229   PLPDVLWRRSAGGGNM-PLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSAS 284
              +P V W    GG  + P  RV    +G   +L L +V L + GE    A++ +      
Sbjct: 11939 GIP-VEW--FLGGTKLEPSDRVVTRAEGRSHTLTLRDVKLTEAGEVKLTAKDFL----TQ 11991

Query: 285   GYLTVYDPPSINLSP-NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDK 343
               L V +PP     P     VE    A   C  + + +  + W  +G            K
Sbjct: 11992 AQLIVNEPPVEFTKPLEDQTVEEEATAELECEVS-KEKAEVRWFRDGQEI-----RKTKK 12045

Query: 344   YHATAVFDGV-TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN 402
             Y   A  DG    L I+D   +DS+ T  C A ++  S+F+         +  PP +   
Sbjct: 12046 YDMVA--DGCKRKLVIHDCTLDDSK-TYTCDAKHFKTSAFL---------NVEPPYVEFT 12093

Query: 403   GPSNQT-LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS- 460
              P +   +  K  A F C  +      + W+ +G  + +  +  + ++G   +  + KS 
Sbjct: 12094 KPLHDVEVKEKESARFEC-EVSRESAKVRWFRDGNEIRKGKKYEMISEGVKRILIISKSV 12152

Query: 461   --DSGTYTCVA 469
               D   Y C A
Sbjct: 12153 FDDEAEYECDA 12163



 Score = 48.0 bits (109), Expect = 0.002
 Identities = 61/242 (25%), Positives = 95/242 (39%), Gaps = 32/242 (13%)

Query: 374   AVNYAGSSFVRGKLTVTSDDDR--PPPIITNGPSNQTLPIKSMAVFPCTAICT--PEPII 429
             AVN AG         V    DR  PP +  +    + + + +  V    A  +  P P I
Sbjct: 16165 AVNAAGVGEPGEVADVIEVKDRTIPPEVDLDATVKEKIVVHAGGVIRILAYVSGKPAPEI 16224

Query: 430   AWYFEGEALIQNHRRNVTN-DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPI 488
              W  +   L +      T+    LV+K   +   G YT  A +  G+     A++V+   
Sbjct: 16225 IWNRDDAELPKEAAVETTSISSALVIKSCLRQHQGIYTLTAKNAGGER--KKAVIVE--- 16279

Query: 489   NPNIHFFRAADVSSLPGPPTKPIT-HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRET 547
                        V  +PGP   P +  N+T+ S  L+W      G S+I  Y +E   RE 
Sbjct: 16280 -----------VLDVPGPVGLPFSGENLTNDSCKLTWYSPEDDGGSAITNYIIE--KREA 16326

Query: 548   LSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
                     + RGW  +   V + + VV+ LI G  Y F +  EN  G+   +  +  V +
Sbjct: 16327 --------DRRGWTSVTYTVTRHNAVVQGLIDGKGYFFRIAAENIIGMGPFTETAAPVVI 16378

Query: 608   GD 609
              D
Sbjct: 16379 KD 16380



 Score = 48.0 bits (109), Expect = 0.002
 Identities = 31/107 (28%), Positives = 45/107 (42%), Gaps = 11/107 (10%)

Query: 504   PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
             PGPP  P    +    +T+ W+     G  SI GY +E   +  +           WV +
Sbjct: 18061 PGPPDAPEVTKIGKDEMTVVWAPPENDGGKSITGYILERKEKRAVR----------WVPV 18110

Query: 564   ARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
              +  + +    V +LIP   Y F V+ EN  GL  PS  S  +T  D
Sbjct: 18111 TKSPISERRMKVTNLIPNHDYQFRVKAENEVGLGEPSKASRPITAKD 18157



 Score = 47.6 bits (108), Expect = 0.002
 Identities = 47/175 (26%), Positives = 68/175 (38%), Gaps = 29/175 (16%)

Query: 425   PEPIIAWYFEGEALIQNHRRNVTNDGTL---VLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
             P P + W  +G +L Q  R NV    TL    +KD  + D+G Y    ++  G  V S  
Sbjct: 25057 PSPEVTWKKDGHSLKQTTRVNVLTSKTLSKITIKDATREDAGKYEITLTNTFG--VKSAE 25114

Query: 482   LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541
             + V               V   PGPP       ++   ++LSW      G   I  Y VE
Sbjct: 25115 ISVI--------------VLDKPGPPGAIKVEEISADFISLSWDPPIYDGGCQINNYVVE 25160

Query: 542   VFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
                R+T         +  W +++  V +T   V  L  G  Y F +  EN +G S
Sbjct: 25161 --KRDT--------TTTAWQIVSATVARTSIKVSRLTQGTEYQFRIAAENRYGKS 25205



 Score = 47.6 bits (108), Expect = 0.002
 Identities = 36/106 (33%), Positives = 53/106 (50%), Gaps = 10/106 (9%)

Query: 506   PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565
             PP++P   N+T TSV+LSW++    G + + GY VE   R  L       + R       
Sbjct: 25322 PPSQPRVMNITRTSVSLSWTKPEFDGGAKVTGYIVE---RSELP------DGRWLKCNFT 25372

Query: 566   RVHQTHYVVKSLIPGITYMFIVRTENSHGL-SGPSPVSDSVTVGDD 610
              + +T++ V  LI    Y F +  +N+ GL S PS  +  VTV DD
Sbjct: 25373 NLQETYFDVTGLIEDQRYDFRIIAKNAAGLFSEPSESTGPVTVKDD 25418



 Score = 47.6 bits (108), Expect = 0.002
 Identities = 103/495 (20%), Positives = 195/495 (39%), Gaps = 57/495 (11%)

Query: 134   GSPEPNVYW--KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG-TRE 190
             G  +   YW  KK   T+L+  ++++  V+  +  +    +    +++  A N AG ++ 
Sbjct: 28500 GGSQVTGYWIEKKERNTILWVRENKIPCVEC-HYKVSTLIEGLEYQFRVYAMNIAGLSKA 28558

Query: 191   SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV----GGDPLPDVLWRRSAGGGNMPL 246
             S  +   + + P    G  +V   T +SV+ +  V    GG  +   +  R A   +   
Sbjct: 28559 SEPSRPVLALNPVDPPGTPEVYDVTKTSVSIRWSVPFNDGGSKIVGYVVERKASSDDEEA 28618

Query: 247   GRVK----VLDDGSLRLDNVILADEGEYSCEAENSVGAVS----ASGYLTV---YDPPSI 295
               +K     + +    + +++  ++ E+   A N  G  S    +SG +T    Y PP  
Sbjct: 28619 RWLKCNYTTITENFFTVTSLVEGEQYEFRVIARNGAGVHSMPSASSGLITCKDEYTPPKA 28678

Query: 296   NLSPN----SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
              L       ++++ +G+         G+PEP +FW+ +G++  + PG   +KY  T    
Sbjct: 28679 ELDSKLVGETISIRAGSDLVLDAAVGGKPEPKVFWA-KGDKE-LDPG---EKYSLTYTST 28733

Query: 352   GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
                 + I   D+ND+   I+ +  N +G       + V         + T GP   T+ I
Sbjct: 28734 RAMAI-IKSCDRNDTGRYIL-TVKNASGIKTSAVNVKV---------LDTPGPPAGTITI 28782

Query: 412   KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
               +    CT +    P+          I   RR  +    +++    +++  T +CV++ 
Sbjct: 28783 SRVTDEKCT-VSWKIPLEDGGDHVSHYIV-ERRETSRLNWVIM----ETECKTLSCVSTK 28836

Query: 472   --RHGKYVW--SGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527
               ++ +Y++   G       +        A +  ++P PP  P    +    V + W + 
Sbjct: 28837 LIKNNEYIFRVRGVNKYGPGVPLESEPVIARNAYTVPTPPGTPDITAIGKEHVIIEWFKP 28896

Query: 528   NKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIV 587
                G S I  Y V+   RE  S   T  N          ++ T   +  L+ G  Y F V
Sbjct: 28897 ENDGGSEIKNYLVD--KREKSSVRWTRVNK------TYTIYDTRLKITGLLEGSDYQFRV 28948

Query: 588   RTENSHGLSGPSPVS 602
                N+ G S PS  S
Sbjct: 28949 SAVNAAGTSAPSDAS 28963



 Score = 47.6 bits (108), Expect = 0.002
 Identities = 53/220 (24%), Positives = 84/220 (38%), Gaps = 17/220 (7%)

Query: 202   PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DG---SL 257
             P+      D+  +  ++ TF  +V G P P V W ++         ++KV +  G    L
Sbjct: 30561 PFFKDELRDMCVKYKANATFVTKVVGHPKPVVKWYKNGKEILADGAKIKVQEFKGGYFQL 30620

Query: 258   RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL-----SPNSVNVESGNVARF 312
              + N    D   Y   A N +G++S S  L V  P  I L        +V+   G V   
Sbjct: 30621 VISNADENDAAAYQIRATNQLGSISTSMNLDVEVPAKIYLPLHLQGMGAVHAIRGEVVTI 30680

Query: 313   TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT-INDTDKNDSRNTIV 371
                 +G+P+P + W  +G   I     +   YH   +    T L  +    + DS   I+
Sbjct: 30681 KIPISGKPDPVVTWQ-KGQEII-----NNTAYHQVIITRSFTSLVFLKGVQRKDSGYYII 30734

Query: 372   CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
             C A N  G      +L V    D P  +  +     TL +
Sbjct: 30735 C-AKNRFGMDKQTVELDVADVPDPPKDVKVSDIGRDTLTL 30773



 Score = 47.2 bits (107), Expect = 0.003
 Identities = 45/156 (28%), Positives = 65/156 (41%), Gaps = 18/156 (11%)

Query: 457   LDKSDSGTYTCVA-SSRH--GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITH 513
             +D+ D+ T+  +  SSR   GKY    +L + +P      F R   V   PGP       
Sbjct: 18324 VDQIDTMTFLVIPESSREDSGKY----SLTLSNPSGEKAVFVRVK-VLDTPGPVGGLDAT 18378

Query: 514   NVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYV 573
             ++T TS  L+W      G S IL Y VE   RE         + + W      + +T + 
Sbjct: 18379 DITKTSCQLAWLPPENDGGSPILNYIVE--KREV--------DRKTWTNCTNDLKKTSFK 18428

Query: 574   VKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
             + +L PGI Y F V   N +G+  P     S    D
Sbjct: 18429 ITNLTPGIEYYFRVMAVNKYGIGLPQDSPKSYLATD 18464



 Score = 47.2 bits (107), Expect = 0.003
 Identities = 27/85 (31%), Positives = 44/85 (51%), Gaps = 2/85 (2%)

Query: 211   VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR--VKVLDDGSLRLDNVILADEG 268
             +V + G++V  +  V G P+P V+W++      +  G    + +   SL L +V   + G
Sbjct: 18974 IVVKAGANVCLEAEVYGKPMPKVVWKKDGAPLKLAEGMKMTQKVHHLSLELFSVTRKESG 19033

Query: 269   EYSCEAENSVGAVSASGYLTVYDPP 293
             EY+  AEN  G+ SA+  L V D P
Sbjct: 19034 EYTITAENPSGSKSANIKLKVLDKP 19058



 Score = 47.2 bits (107), Expect = 0.003
 Identities = 38/108 (35%), Positives = 46/108 (42%), Gaps = 11/108 (10%)

Query: 503   LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
             +PGP   P+  NVT   +T++W      G ++ILGY VE   RET   N        WV 
Sbjct: 19158 VPGPCEPPVITNVTRDHMTVTWKAPANDGKATILGYMVE--KRETQDLN--------WVK 19207

Query: 563   IARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
             + RR V         L  G  Y F V   N  GL  PS  S  V   D
Sbjct: 19208 VNRRPVIDRTIKAGGLTEGTEYEFRVIALNKAGLGKPSDPSSGVLALD 19255



 Score = 47.2 bits (107), Expect = 0.003
 Identities = 36/128 (28%), Positives = 53/128 (41%), Gaps = 13/128 (10%)

Query: 484   VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543
             V +P  P+  +++A D +  PGPP  P   + + T+V+L+WS+    G + + GY VE  
Sbjct: 24619 VGTPSEPS-EYYKACDATYPPGPPNNPKVTDHSSTTVSLAWSRPIYDGGAPVSGYIVEA- 24676

Query: 544   SRETLSGNNTPRNSRGWVVIA--RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPV 601
                         N   W V      V  TH+ VK L     Y F +   N  G      V
Sbjct: 24677 ---------KDINEDEWTVCTPPTGVQATHFTVKKLKENAEYNFRICAVNIEGAGEHVDV 24727

Query: 602   SDSVTVGD 609
               SV   +
Sbjct: 24728 PGSVIAAE 24735



 Score = 47.2 bits (107), Expect = 0.003
 Identities = 33/113 (29%), Positives = 46/113 (40%), Gaps = 11/113 (9%)

Query: 497   AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556
             A  +S  P PP K    +VT  +VTLSW + +  G S I GY VE+ +          + 
Sbjct: 24924 AVKISQAPLPPGKITVIDVTRHTVTLSWEKPDHDGGSKITGYMVEMMT----------KG 24973

Query: 557   SRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
             S  W      +      ++ L  G  Y F +   N  G S P P+   V   D
Sbjct: 24974 SDKWTACV-TIKALEATIEGLTTGEEYSFRITAINDKGKSDPKPLGAPVVARD 25025



 Score = 47.2 bits (107), Expect = 0.003
 Identities = 42/155 (27%), Positives = 71/155 (45%), Gaps = 14/155 (9%)

Query: 74    GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC---- 129
             G V +    +  +A N  G ++ R+A   V +  +E R+EP +  S+  D  ++ C    
Sbjct: 28239 GLVENTEYEFRVKAQNDAGISQPRDALASVII--KEPRIEPTADLSSI-DKQLITCKTGN 28295

Query: 130   -----LPPRGSPEPNVYWKKNGQTLL-FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
                  +P  G P P V WK     L   D  S     D   L+++DA++ D+G+Y     
Sbjct: 28296 SFAIDIPISGRPAPKVTWKLEEMKLKETDRVSIKISKDRTTLLVKDAKRGDSGKYYLTLE 28355

Query: 184   NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSS 218
             NAAG++   +  + I  +P   TGP ++   +  S
Sbjct: 28356 NAAGSKTFTVTVIVIG-RPTPPTGPVEISGVSSES 28389



 Score = 47.2 bits (107), Expect = 0.003
 Identities = 45/167 (26%), Positives = 67/167 (40%), Gaps = 14/167 (8%)

Query: 136   PEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGTRESAI 193
             PEP+V W K G  +  D        D G   L+I +   +D   Y  +A N  G  +S  
Sbjct: 31349 PEPSVTWLKAGHRIKPDPKKYTFTSDKGLYQLMIHNVDLSDDAEYTVVANNKFG-EDSCK 31407

Query: 194   ATLKI--H------IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM- 244
             A L +  H      ++P       ++    G SV F  RV G P P + W ++       
Sbjct: 31408 ARLNVAPHAVAEDTMRPMFKRLLANIDCVEGQSVRFDLRVSGTPAPTLKWEKNGKPLEFR 31467

Query: 245   PLGRV--KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
             P   V  + +D   L +   ++ D G Y   A N+ G+ S    L V
Sbjct: 31468 PQVEVVQEDVDYFILHIRETLIEDSGTYRVTATNTAGSASCQATLKV 31514



 Score = 46.8 bits (106), Expect = 0.004
 Identities = 37/116 (31%), Positives = 48/116 (41%), Gaps = 13/116 (11%)

Query: 497   AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE---VFSRETLSGNNT 553
             A D   +P PP  P+  + T  SVTLSW      G   I GY +E       E L  N T
Sbjct: 16775 AKDPIVIPSPPVLPVAIDKTKESVTLSWQPPKDCGRGKIFGYLLEYQKAGDEEWLQVNQT 16834

Query: 554   PRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
             P +             T + V +L  G  Y F V+  N+ G S P+ V + V   D
Sbjct: 16835 PDS----------CPSTTFKVINLEDGALYRFRVKAVNAAGESEPAYVPEPVRAQD 16880



 Score = 46.8 bits (106), Expect = 0.004
 Identities = 36/107 (33%), Positives = 51/107 (47%), Gaps = 9/107 (8%)

Query: 506   PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI-A 564
             PP  P  ++VT TSV++ WS     G S I+GY VE   R+  S +   R    W+    
Sbjct: 28573 PPGTPEVYDVTKTSVSIRWSVPFNDGGSKIVGYVVE---RKASSDDEEAR----WLKCNY 28625

Query: 565   RRVHQTHYVVKSLIPGITYMFIVRTENSHGL-SGPSPVSDSVTVGDD 610
               + +  + V SL+ G  Y F V   N  G+ S PS  S  +T  D+
Sbjct: 28626 TTITENFFTVTSLVEGEQYEFRVIARNGAGVHSMPSASSGLITCKDE 28672



 Score = 46.8 bits (106), Expect = 0.004
 Identities = 73/305 (23%), Positives = 117/305 (38%), Gaps = 40/305 (13%)

Query: 302   VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
             VNV +G          GRP P   WS  G +  +   + R K   TA F   T LT+ +T
Sbjct: 29380 VNVPAGKPIVLNIPIKGRPAPVCSWSFGGVK--MKDKLDRIKIETTAKF---TKLTVRET 29434

Query: 362   DKNDSRN-TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
               +D+ + T+    V+   +  +R              II + P     P+K   V   +
Sbjct: 29435 TIDDTGDYTLNVKNVSGTATEVIR-------------VIILDKPGVPVGPMKIEEVDATS 29481

Query: 421   AICTPEPIIAWYFEGEALIQNH---RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
               C+ EP      +G A +  +   +R+    G + + +        +T +      +YV
Sbjct: 29482 VTCSWEPPQK---DGGANVSGYIVEQRDAHRPGWMSVSESVTRPVFKFTRLVEGT--EYV 29536

Query: 478   WSGALLVDSPINPNIH--FFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSI 535
             +  A      I   +         V ++PG P+ P   +V+   +TL+W+     G S+I
Sbjct: 29537 FRVAATNRFGIGGFLQSEVVECKSVKTVPGAPSTPEILDVSHDGMTLTWTPPEDNGGSTI 29596

Query: 536   LGYQVEVFSRETLSGNNTPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMFIVRTENSHG 594
              GY +E               S  W+ I +  V  T Y    LI G+ Y + V   NS G
Sbjct: 29597 AGYIIE----------RKEAGSDRWLSINKNPVTMTRYRATGLIEGLEYEYRVTAINSRG 29646

Query: 595   LSGPS 599
                PS
Sbjct: 29647 TGKPS 29651



 Score = 46.4 bits (105), Expect = 0.005
 Identities = 71/305 (23%), Positives = 111/305 (36%), Gaps = 21/305 (6%)

Query: 10    EAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
             EAP      L D T+   + A  +C      +  I+WY+ G  +           G    
Sbjct: 12536 EAPTDFTAQLSDQTITEFEDAEFSCELTKEKAD-IKWYRDGREIREGPRYQFERDGKTCR 12594

Query: 69    LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
             LR    R   +     CE        R+R A L V     E    P       G  VV E
Sbjct: 12595 LRIKECRPDDE-----CEYACGVDDKRTR-ARLFVEETPVEIVRPPTDVFEPPGSDVVYE 12648

Query: 129   CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAA 186
                 +   E  V W +N  T++  GD    + +G    L + + R  D G Y+ IA++  
Sbjct: 12649 VELNKDRVE--VKWLRNNMTIV-QGDKYQMMSEGKIHRLQVCEIRPRDQGEYRVIAKD-- 12703

Query: 187   GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
                + A A L++   P + T  +D+V   G            PL +  W  +    ++P 
Sbjct: 12704 ---KDARAKLELAAVPTIKTLDQDLVTDAGKPFVMGVPYNAYPLAEAEWFYN--DISLPK 12758

Query: 247   GRVKV-LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
               +   +D    RL +   ++EG Y    +N  G   A   L V D P    +   V+  
Sbjct: 12759 DNIHTSIDRTEYRLKDPKKSEEGRYKIIVQNKHGKGEAFINLKVIDVPGPVKNLQVVDTA 12818

Query: 306   SGNVA 310
              G ++
Sbjct: 12819 DGEIS 12823



 Score = 46.4 bits (105), Expect = 0.005
 Identities = 82/359 (22%), Positives = 139/359 (38%), Gaps = 42/359 (11%)

Query: 259   LDNVILADEGEYSCEAENSVGAVS---ASGYLTVYDP---PSINLSP---NSVNVESGNV 309
             L+ ++   E E+  +A+N  G      A   + + +P   P+ +LS      +  ++GN 
Sbjct: 28237 LEGLVENTEYEFRVKAQNDAGISQPRDALASVIIKEPRIEPTADLSSIDKQLITCKTGNS 28296

Query: 310   ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
                    +GRP P + W +E  +         D+       D  T+L + D  + DS   
Sbjct: 28297 FAIDIPISGRPAPKVTWKLEEMKL-----KETDRVSIKISKDRTTLL-VKDAKRGDSGKY 28350

Query: 370   IVCSAVNYAGSSFVRGKLTVTSDDDRPP-PIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428
              + +  N AGS      + V      P  P+  +G S+++  +                I
Sbjct: 28351 YL-TLENAAGSKTFTVTVIVIGRPTPPTGPVEISGVSSESCVLTWGEPSDDGGTDITNYI 28409

Query: 429   IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG--KYVWSGALLVDS 486
             +     G    Q    +V    T+ +  L K    T+   A ++ G  K + S A++ + 
Sbjct: 28410 VEKRESGSTTWQVVNSSVKRT-TIKVTHLTKYMEYTFRVSAENKFGVSKSIESQAIVAEH 28468

Query: 487   PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRE 546
             P            +S  P PPT+P   +V   ++++ W      G S + GY +E   R 
Sbjct: 28469 PF-----------IS--PSPPTRPDVVSVCANAISIRWDVPYHDGGSQVTGYWIEKKERN 28515

Query: 547   TLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605
             T+      R ++   V      + HY V +LI G+ Y F V   N  GLS  S  S  V
Sbjct: 28516 TILW---VRENKIPCV------ECHYKVSTLIEGLEYQFRVYAMNIAGLSKASEPSRPV 28565



 Score = 46.4 bits (105), Expect = 0.005
 Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 3/77 (3%)

Query: 415   AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN---DGTLVLKDLDKSDSGTYTCVASS 471
             A F C     P P + W  EG  ++ +HR +V+      TL +  ++ SD G YT V  +
Sbjct: 32154 ARFVCDIDGEPAPTVTWMHEGRTVVSSHRIHVSTTQYKSTLEISSVEYSDEGNYTVVVEN 32213

Query: 472   RHGKYVWSGALLVDSPI 488
               GK      L ++ PI
Sbjct: 32214 SEGKQEARCTLAINKPI 32230



 Score = 46.0 bits (104), Expect = 0.006
 Identities = 38/135 (28%), Positives = 53/135 (39%), Gaps = 12/135 (8%)

Query: 494   FFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNT 553
             F++A D    P  PTK    + T TS+TL W +    G S I  Y +E            
Sbjct: 26792 FYKAYDPIDPPSEPTKLRVVDSTKTSITLGWVKPVYDGGSEITSYVIE----------QR 26841

Query: 554   PRNSRGWVVIARR--VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDS 611
               +   WV I+ +  V  T +VV  L PG+ Y + V   N  G      +   V   D  
Sbjct: 26842 IADETEWVTISSKGEVRTTEFVVSHLKPGVYYYYRVSAVNCVGTGRSIEIVQPVQAKDIL 26901

Query: 612   NSLWEGTGVSNSTEY 626
                     +S ST+Y
Sbjct: 26902 EEADVDLDISMSTQY 26916



 Score = 45.2 bits (102), Expect = 0.011
 Identities = 80/311 (25%), Positives = 124/311 (39%), Gaps = 40/311 (12%)

Query: 15   IEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRS--ILPAGGLFFLR 70
            I +PL DVTVA  Q A + C    +P+   +W K G  V  SD  RS  I     L F+ 
Sbjct: 2395 INRPLHDVTVAESQTAVMECEV-ANPTSEGKWLKDGHSVDFSDIVRSEDIDAVRRLIFVI 2453

Query: 71   ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC- 129
                    D G Y  +  NS       +A L V  ++ +  L+ ++    Q     LE  
Sbjct: 2454 TR----PQDIGEYTYQVANS-----KTSANLRVEAVKIKKTLKNQTVTETQEAVFSLELT 2504

Query: 130  -LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAA 186
             L  +GS      W KNG   +   D     VDG    L I++    D   Y       +
Sbjct: 2505 HLDVKGS-----QWIKNG-VEIEPSDKYEITVDGLVHTLKIKNCNSQDESVYGFKLGKLS 2558

Query: 187  GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
                  + T+KI      +  P+DV +    + +F+  +  D +P V W         P 
Sbjct: 2559 ANARLNVETIKI------VKKPKDVTSLVNGTASFELSLSHDDIP-VKW-MFKNQELKPS 2610

Query: 247  GRVKVLDD---GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
              V+++ +     L + NV  +++GEY+      VG +  S YL V +   +     ++ 
Sbjct: 2611 ANVQIMSERKAHKLVIQNVEESNDGEYTA----VVGHLQCSAYLHV-ESLRVTKPLKNLE 2665

Query: 304  VESGNVARFTC 314
            V   +VA F C
Sbjct: 2666 VPETHVATFEC 2676



 Score = 45.2 bits (102), Expect = 0.011
 Identities = 54/223 (24%), Positives = 90/223 (40%), Gaps = 26/223 (11%)

Query: 7     TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRW----YKGGV----------LV 52
             T   AP +I+ PL V     +P  +   A  + S ++ W    Y GG           L+
Sbjct: 16370 TETAAPVVIKDPLSVP---ERPEDVEVTAITNDSISVAWRSPKYDGGSDITSYVLEVRLI 16426

Query: 53    VSDTHRSILPAGGLFFLRATH-GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE--- 108
               D    I     L   + TH G     +  +   A N  G  +   +T  V   +E   
Sbjct: 16427 GQDNFSRIAKEDKLMDRKFTHAGLKEGSSYEFRVSAVNQIGQGKPSFSTKPVTCKKEFEP 16486

Query: 109   -EFRLEPESKQSAQ-GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NL 165
                 LE   K   + G+T +++     G PEP + W KN + L  + +  +       +L
Sbjct: 16487 PNLDLEFRDKLVVRVGETCIIQSRYT-GKPEPTIKWFKNDEELQANEEIALTTAKNRLSL 16545

Query: 166   VIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208
              I+ A++  +G+Y  +  N+ GTR+  I T+ +  +P    GP
Sbjct: 16546 TIEKAKRDHSGKYMVVLENSIGTRK-GICTVNVVDRPQPPEGP 16587



 Score = 45.2 bits (102), Expect = 0.011
 Identities = 20/53 (37%), Positives = 31/53 (58%)

Query: 489   NPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541
             +P+  F++A D    PGPP  P   + T +S+T++W++    G S I GY VE
Sbjct: 21377 SPSSPFYKACDTIFQPGPPGNPRVLDTTKSSITIAWNKPVYDGGSDITGYIVE 21429



 Score = 45.2 bits (102), Expect = 0.011
 Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 6/90 (6%)

Query: 134   GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIARNAAGTRE 190
             G P+P + W K+G  L     +R+++ D  +   L I+DA + D G Y  +  N  G +E
Sbjct: 22890 GHPKPTITWNKDGSAL--KQTTRVNVADTAHHTTLTIKDATREDGGMYNIVVANVLGQQE 22947

Query: 191   SAIATLKIHIKPYLITGPEDVVAQTGSSVT 220
             + +  + +  KP   TGP  +   +  S+T
Sbjct: 22948 ATVEIIILE-KPGPPTGPVRIDEVSAESIT 22976



 Score = 44.8 bits (101), Expect = 0.015
 Identities = 57/220 (25%), Positives = 95/220 (43%), Gaps = 18/220 (8%)

Query: 17  QPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL--RAT- 72
           QPL   VA     AT   +  G+P P + W++ G ++ +    + LP   + F   RA  
Sbjct: 10  QPLQSVVALEGSAATFEAQVSGNPVPEVSWFRDGQVLTA----AALPGAQISFSDGRAVL 65

Query: 73  --HGRVHSDAGVYWCEATNSYGTARSRNATLHVA-VLREEFRLEPESKQSAQGDTVVLEC 129
                  + +G +   ATN  G A S    L  A      F    +S    QG  V L+ 
Sbjct: 66  MIPAVTAAHSGRFSVRATNGAGQATSTAELLVTAETAPPNFIQRLQSLTVRQGSQVRLD- 124

Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAG 187
           +   G P P V + + G  +    D ++ + DG   +L+I +A   D+G Y   A N++G
Sbjct: 125 VRVTGIPAPVVKFYREGAEIQSSADFQI-VQDGDLYSLLIAEAFPEDSGTYSVSASNSSG 183

Query: 188 TRESAIATLKIHIKPYLITGPED--VVAQTGSSVTFQCRV 225
            R ++ A L +  +   +   +   +++ +  S T Q RV
Sbjct: 184 -RATSTAELLVQGEEEAVPAKKSKTIISASQISQTRQTRV 222



 Score = 44.8 bits (101), Expect = 0.015
 Identities = 33/112 (29%), Positives = 51/112 (45%), Gaps = 9/112 (8%)

Query: 505   GPPTKPITHNVTDTS---VTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV 561
             GPP+ P   ++T+ +   + ++W    K G S I+GY +E+    T        NSR   
Sbjct: 13998 GPPSPPQELHITEAARDHICIAWKAPEKNGGSPIIGYHIELCEAGTEKWMRV--NSRPVK 14055

Query: 562   VIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNS 613
              +  R        + ++P   Y F VR  NS G S PS +S++V   D   S
Sbjct: 14056 ELKYRAGDE----EGIVPEKEYTFRVRAVNSVGASEPSDISENVFAIDSDCS 14103



 Score = 44.8 bits (101), Expect = 0.015
 Identities = 24/78 (30%), Positives = 44/78 (56%), Gaps = 6/78 (7%)

Query: 122   GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRY 178
             GD + ++ +P RG P P V WKK+G +L     +R++++       + I+DA + DAG+Y
Sbjct: 25044 GDDLKID-VPFRGRPSPEVTWKKDGHSL--KQTTRVNVLTSKTLSKITIKDATREDAGKY 25100

Query: 179   QCIARNAAGTRESAIATL 196
             +    N  G + + I+ +
Sbjct: 25101 EITLTNTFGVKSAEISVI 25118



 Score = 44.8 bits (101), Expect = 0.015
 Identities = 26/90 (28%), Positives = 46/90 (51%), Gaps = 6/90 (6%)

Query: 134   GSPEPNVYWKKNGQTLLFDGDSRMHL---VDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
             G P P + W K+G+ +  +  +R  +   +    L+++DA + D+G+Y    +N AGTR 
Sbjct: 25450 GRPIPVISWAKDGKEI--EAKARFEISSTLTSTTLIVRDAIRRDSGQYVLTLQNVAGTRS 25507

Query: 191   SAIATLKIHIKPYLITGPEDVVAQTGSSVT 220
              A+   K+  +P   +GP D+   T    T
Sbjct: 25508 LAV-NCKVLDRPGPSSGPLDITGLTAEKCT 25536



 Score = 44.8 bits (101), Expect = 0.015
 Identities = 44/181 (24%), Positives = 76/181 (41%), Gaps = 30/181 (16%)

Query: 422   ICTPEPIIAWYFEGEALIQNHRRNVTN--DGTLV-LKDLDKSDSGTYTCVASSRHGKYVW 478
             +  P+P I WY +G+ L    + +++N  + T + +++  + ++GTY     +  G    
Sbjct: 26532 VAKPQPTIEWYKDGKELESGAQISISNTTEFTCISVREATRLNTGTYELKIKNSLGSAYA 26591

Query: 479   SGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSILG 537
             +  +LV                   PGPP   I    +T  ++T+ W      G + +  
Sbjct: 26592 AVRVLVQDK----------------PGPPAGEIQFKKITADTMTIMWDPPADEGGAMVTH 26635

Query: 538   YQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSG 597
             Y VE   RET        +   W +I+ ++      V  LI G  Y+F VR  N HG+  
Sbjct: 26636 YIVE--KRET--------SRIMWSIISEKLQDCIVTVPRLIKGNEYIFRVRGVNKHGVGD 26685

Query: 598   P 598
             P
Sbjct: 26686 P 26686



 Score = 44.4 bits (100), Expect = 0.019
 Identities = 83/331 (25%), Positives = 133/331 (40%), Gaps = 34/331 (10%)

Query: 497   AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556
             A D  + P  P  P   + T  SVTL+W+   K G   I GY +E+          T   
Sbjct: 15471 ADDPLTPPSMPAAPEIADKTKHSVTLAWTPPAKDGGRPIKGYIIEI------QDEGTSEW 15524

Query: 557   SRGWVVIARRVH-QTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLW 615
             +R  V  A  +H  T + + +L     Y F +   N  G S PSP +  V + D   +  
Sbjct: 15525 AR--VNDAENLHPSTVFTIPNLPELKKYRFRIIAVNEIGESEPSPRTSEVRIEDIKTAPK 15582

Query: 616   EGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLF-IYFRPLDNI 674
                 +S          T      I AT       K+ WE       E    ++  P+D+ 
Sbjct: 15583 IFMDISADELLCVRAGTPF---KIPATITGRPAPKVTWEFDGKAKTEKKDRLHILPVDS- 15638

Query: 675   TIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGP 734
              +E    T + +  VS      LR ++    + I    K   K  N RV   + DVP G 
Sbjct: 15639 QVESTDTTSVVTVPVS------LRSHSGR--YTITAKNKSGQKHVNVRV--NVLDVP-GA 15687

Query: 735   PINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPA--NKSMVAINTTVHQA 792
             P  +++  +  TT+ L W  P+    +G   G  +   +++  A   K+    N T   +
Sbjct: 15688 PKELKVTDVTRTTMRLIWKLPD---NDG---GERIKSYFIEKKAVNGKAWTVANATC-AS 15740

Query: 793   TSLIMTNLTSGVSYSVQIAAETIIGLGPFSQ 823
              + +++NL  G  Y  ++ AE  +G GPF++
Sbjct: 15741 MAFVVSNLLEGQDYFFRVRAENRLGFGPFTE 15771



 Score = 44.4 bits (100), Expect = 0.019
 Identities = 35/115 (30%), Positives = 53/115 (46%), Gaps = 12/115 (10%)

Query: 496   RAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPR 555
             +A ++ + PGPPT  +T + T ++V L W      G S I GY VE + +E         
Sbjct: 16082 KARNLFTPPGPPTPKVT-DCTKSTVDLEWIPPLNDGGSMITGYFVE-YKQE--------- 16130

Query: 556   NSRGWVVIA-RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
                 W  +  + +  T +VV  L     Y F VR  N+ G+  P  V+D + V D
Sbjct: 16131 GQEEWEKVKDKEIRGTKFVVPGLKELGLYRFRVRAVNAAGVGEPGEVADVIEVKD 16185



 Score = 44.0 bits (99), Expect = 0.025
 Identities = 35/96 (36%), Positives = 46/96 (47%), Gaps = 13/96 (13%)

Query: 504   PGPPTKPITHNVTD-TSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
             PGPP K + H   D T V L W+  ++ G S I G+ VE +  E           + W+V
Sbjct: 17079 PGPP-KDLHHVDADKTEVWLQWNWPDRTGGSDITGFLVE-YQEE---------GEKDWIV 17127

Query: 563   IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
               + V      V  L  G TY F V+TEN+ GLS P
Sbjct: 17128 F-KTVSIPECHVTGLEEGKTYRFRVKTENAIGLSRP 17162



 Score = 44.0 bits (99), Expect = 0.025
 Identities = 85/347 (24%), Positives = 127/347 (36%), Gaps = 43/347 (12%)

Query: 269   EYSCEAENSVGAVSA----SGYLTVYDP---PSINLSPNS---VNVESGNVARFTCTATG 318
             E+   A NS GAVS     S  +   D    P I+   +    V V++G++ +     TG
Sbjct: 21064 EFRVLARNSAGAVSKPSKPSEVIVCRDDIEEPKIDADASFSSVVVVKAGDIFKLDAHVTG 21123

Query: 319   RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
             RP P++ W+ +G        M           D  + L   D+ + D       +A N  
Sbjct: 21124 RPIPSIVWTKDGKELEDTAKME------IKTLDFYSCLINKDSLRRDG-GAYTLTASNPG 21176

Query: 379   GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438
             G +     + V    DRP      GP    L +  M V  C     P P+     + E  
Sbjct: 21177 GFAKFVFNVKVL---DRP------GPPEGPLHVTDMTVEKCVLSWLP-PLHDGGGKIEYY 21226

Query: 439   IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAA 498
             I   R       T V  DL  +    Y      +  +Y++    +    +   +    A 
Sbjct: 21227 IIQRRETSRLTWTNVATDLQVN---RYKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPAV 21283

Query: 499   DVSS-LPG-PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556
               +  +P  PP  P    +T  S+ + W      G SSI  Y +E   R   +G      
Sbjct: 21284 ATNPYVPSDPPQAPEVTAITKDSMVVCWGHPEYNGGSSINTYIIE---RRDKTGLR---- 21336

Query: 557   SRGWVVIARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602
                WV   +R V    + V  L PG  Y + +  EN+ GLS PSP S
Sbjct: 21337 ---WVKCNKRTVTDLRFKVSGLTPGHEYEYRILAENAAGLSAPSPSS 21380



 Score = 43.6 bits (98), Expect = 0.034
 Identities = 30/91 (32%), Positives = 45/91 (49%), Gaps = 4/91 (4%)

Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM-HLVDGG--NLV 166
           F  +P  ++  +G +VV  C    GSP+P++YWKK+G  L      R+ H  D G   L 
Sbjct: 877 FVKKPVVQKLVEGGSVVFVC-QIGGSPKPHIYWKKSGVPLTTGYRYRVSHNKDTGECKLE 935

Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATLK 197
           I      DAG Y   A+N  G   ++ + L+
Sbjct: 936 ISMTFADDAGEYTIFAKNQHGETSASTSLLE 966



 Score = 43.6 bits (98), Expect = 0.034
 Identities = 34/114 (29%), Positives = 43/114 (37%), Gaps = 11/114 (9%)

Query: 497   AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556
             A D    PGPP       V+ T V L W      G   +L Y +E   +E L        
Sbjct: 13892 AKDTFGTPGPPYNLTITEVSKTHVDLKWEAPQNDGGRPVLRYVIE--KKEKLGTR----- 13944

Query: 557   SRGWVVIARRV-HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
                WV   +      HY V  +I G    F V  EN  G+  PS  +D V + D
Sbjct: 13945 ---WVKSGKTSGPDCHYRVTDVIEGTEVQFQVSAENEAGVGHPSEPTDIVVIED 13995



 Score = 43.6 bits (98), Expect = 0.034
 Identities = 37/104 (35%), Positives = 50/104 (48%), Gaps = 12/104 (11%)

Query: 504   PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
             P  P KP   +VT +S+ ++W + N  GS+ I GY VE   RE         NS  W  +
Sbjct: 14673 PDAPEKPEIKDVTASSMCVTWLEPNDNGSA-IEGYWVE--KREI--------NSTHWARV 14721

Query: 564   ARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVT 606
              R  V      V+ L+ G+TY+F V  EN  G    SP S+  T
Sbjct: 14722 NRTMVPDLEINVEGLLEGLTYIFRVCAENIAGPGKFSPPSEPKT 14765



 Score = 43.6 bits (98), Expect = 0.034
 Identities = 35/114 (30%), Positives = 46/114 (40%), Gaps = 9/114 (7%)

Query: 496   RAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPR 555
             +A DV  +P  P  P+   +   +  +SW Q    G   I  Y VE   +ET   N   R
Sbjct: 16673 KAKDVFKVPDAPQAPVVKEIYKDTALISWLQPAD-GGKPITNYIVE--KKET-KANMWAR 16728

Query: 556   NSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
               +      R    T Y V  L+ G  Y F V  EN  G+  PSP S  +   D
Sbjct: 16729 AGKD-----RIFPNTEYWVPDLLKGCEYEFRVMAENVIGIGDPSPSSKPIYAKD 16777



 Score = 43.6 bits (98), Expect = 0.034
 Identities = 33/105 (31%), Positives = 45/105 (42%), Gaps = 14/105 (13%)

Query: 506   PPTKPIT---HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
             PP++P+    + V+   V LSW +    G S++ GY +E             RNS  WV 
Sbjct: 18760 PPSEPLNCCVNKVSKEFVVLSWEKPVNDGGSALTGYFIE----------RKERNSLLWVR 18809

Query: 563   IAR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVT 606
                  V  T Y    LI G+ Y F V   N  G   PS  +D +T
Sbjct: 18810 TNEVLVRSTEYTCSGLIEGLEYTFRVSAVNKAGQGKPSKQTDFIT 18854



 Score = 43.6 bits (98), Expect = 0.034
 Identities = 36/108 (33%), Positives = 50/108 (46%), Gaps = 11/108 (10%)

Query: 497   AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556
             AA    +PG P  P     T  ++T+SW++ +  G S ILGY +E             +N
Sbjct: 20888 AAYPFDVPGQPGIPQIVAFTKDAMTISWNEPSSDGGSPILGYHIE----------RKEKN 20937

Query: 557   SRGWVVIARRVHQTHYVVKS-LIPGITYMFIVRTENSHGLSGPSPVSD 603
             S  W  I++ V   +    S L+ GI Y F V  EN  GLS  S  S+
Sbjct: 20938 SILWQRISKAVVVGNMFKSSGLMDGIAYEFRVIAENLAGLSKASKPSE 20985



 Score = 43.6 bits (98), Expect = 0.034
 Identities = 83/327 (25%), Positives = 123/327 (37%), Gaps = 47/327 (14%)

Query: 291   DPPSINLSPN---SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
             D P I L       + V +G   R      GRP P + W+ +        G   DK    
Sbjct: 23655 DAPEIELDSELRKGIVVHAGGSMRINIPFKGRPIPEINWTKDD-------GDLPDKAQID 23707

Query: 348   AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG--SSFVRGKLTVTSDDDRPPPIITNGPS 405
                D  T LTIN  D+ND+      +  N AG  S+FV  K+      D P       P 
Sbjct: 23708 KGPD-FTHLTINICDRNDA-GKYTLTLQNSAGTKSAFVSVKVL-----DTP-----GAPQ 23755

Query: 406   NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH---RRNVTNDGTLVLKDLDKSDS 462
             N  L +K +     T +  P P+I    +G + I+N+   +R  T  G   +    K   
Sbjct: 23756 N--LFVKDITRNYVTLVWEP-PLI----DGGSKIKNYIIDKRESTRQGFTNITT--KCSK 23806

Query: 463   GTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTL 522
              ++     +  G Y +      +  I   +    +   +  P    K    +VT T+ +L
Sbjct: 23807 TSFRVGDLTEGGIYYFRVMAENEFGIGLPVETEESVKTADPPLSVGKVTLTDVTKTTASL 23866

Query: 523   SWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGIT 582
             SW + +  G S ILGY +E+           P+ S  W+V A         V  L  G  
Sbjct: 23867 SWDKPDHDGGSRILGYYIEM----------QPKGSEEWIV-ATVCKTCEGTVAGLSSGQE 23915

Query: 583   YMFIVRTENSHGLSGPSPVSDSVTVGD 609
             Y+  V   N  G S P P++  V   D
Sbjct: 23916 YLLRVLAYNEKGKSDPRPLASPVIAKD 23942



 Score = 43.2 bits (97), Expect = 0.044
 Identities = 34/142 (23%), Positives = 62/142 (43%), Gaps = 6/142 (4%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-THRSILPAGGLFFLR 70
            P  +++P     +  Q A  + +  G P P   W+  G  VV+D TH+ ++   G   + 
Sbjct: 1229 PVFVQKPSSFRCSEGQTARFDLKVVGRPMPDTFWFHSGQQVVNDYTHKIVVKEDGTQSMI 1288

Query: 71   ATHGRVHSDAGVYWCEATNSYG-TARSRNATLHVA--VLREEFRLEPESKQSAQGDTVVL 127
                 +  D+G +   A N  G T  S   T+     ++R +F +E     S +  ++V 
Sbjct: 1289 VVPA-MPQDSGEWTVVAQNRAGKTTVSMTLTVEAKENLVRPQF-IEKLKNISVKEGSLVE 1346

Query: 128  ECLPPRGSPEPNVYWKKNGQTL 149
              +   G+P P++ W KN   +
Sbjct: 1347 LAVKAIGNPLPDIVWLKNSDII 1368



 Score = 43.2 bits (97), Expect = 0.044
 Identities = 39/135 (28%), Positives = 62/135 (45%), Gaps = 8/135 (5%)

Query: 692   FEITSLRKYTKYEFFLIPFYKKFEGKPSN-SRVAQTLDDV-PDGPPINIEMFILNTTTVH 749
             F+++ L +  +YEF +    K   G+PS  S+   T D   P GPP N  +     TT  
Sbjct: 20267 FKVSGLSEEIEYEFRVTAENKAGFGEPSEPSQPVMTKDIAYPPGPPSNPRITDTTKTTAT 20326

Query: 750   LKWSPPELQLQNGI-ITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSV 808
               W  P      G+ +TGY +V +  +   +   V   T   + T  +++NL SG  Y  
Sbjct: 20327 FNWGRPFYD--GGLDVTGY-IVEHKKE--GDDDWVQDTTIPLRITEFVVSNLQSGGKYHF 20381

Query: 809   QIAAETIIGLGPFSQ 823
             +++A    GLG  S+
Sbjct: 20382 RVSALNSEGLGEPSE 20396



 Score = 43.2 bits (97), Expect = 0.044
 Identities = 37/128 (28%), Positives = 53/128 (41%), Gaps = 13/128 (10%)

Query: 484   VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543
             V  P  P + +F+AAD    PGPP  P    V+  SV L WS+    G   I  Y VE  
Sbjct: 22455 VGKPSPPTV-YFKAADPVFKPGPPNNPKVAYVSRASVVLHWSKPIYDGGCEIQSYIVE-- 22511

Query: 544   SRETLSGNNTPRNSRGWVVIA--RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPV 601
             + E  S          WV+      + +T +  K L+    Y F +   N  G+   + +
Sbjct: 22512 ACEVTSDE--------WVMCTPPSGITETRFEAKKLLEKHEYKFRICAVNKIGVGETADI 22563

Query: 602   SDSVTVGD 609
               SV + D
Sbjct: 22564 PGSVIIED 22571



 Score = 43.2 bits (97), Expect = 0.044
 Identities = 32/107 (29%), Positives = 42/107 (39%), Gaps = 11/107 (10%)

Query: 504   PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
             PGPP  P        S+ + W +    G S+ILGY +E             +NS  W  I
Sbjct: 23058 PGPPGTPFVSAFNKESMVVEWHKPVSDGGSAILGYHLE----------RKEKNSILWTKI 23107

Query: 564   AR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
              +  +  T Y    L  GI Y F V  EN  G+   S  S+     D
Sbjct: 23108 NKILIQDTRYKTSPLEEGIEYEFRVYAENIVGIGKCSKTSEGCIARD 23154



 Score = 43.2 bits (97), Expect = 0.044
 Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 9/106 (8%)

Query: 504   PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
             PGPPT     + T + + ++W++    G S I+GY +E   + ++      + +RG +  
Sbjct: 25222 PGPPTSLQVSHATKSGMLVTWNRPASDGGSPIVGYHIECKDQSSILWT---KMNRGLIT- 25277

Query: 564   ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
                  +T + V  L  G+ Y + V  EN  G+   +   D V+  D
Sbjct: 25278 -----ETQFKVTGLEEGLQYQYRVYAENIAGIGPCTKACDPVSARD 25318



 Score = 43.2 bits (97), Expect = 0.044
 Identities = 36/120 (30%), Positives = 54/120 (45%), Gaps = 9/120 (7%)

Query: 87    ATNSYGTARSRNATLHVAV-LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
             +++S+    S  A LH A  L       PE      G  + + C    G P P++ W + 
Sbjct: 32640 SSHSHAEETSVRAALHSAQGLAPRIEALPEDISVETGKVLTVACAFS-GEPAPHIEWSRG 32698

Query: 146   GQTLLFDGD-SRMHL---VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201
             G+ L  + D SR H+    D   L+I   ++TDAG Y     N  G   S +AT+ I I+
Sbjct: 32699 GKKLPGEEDSSRFHIETTEDLTTLIITGVKETDAGAYTLKLSNEHG---SDLATVTISIR 32755



 Score = 42.7 bits (96), Expect = 0.059
 Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 4/111 (3%)

Query: 1    MSDDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI 60
            ++ D ++    P I+  P  + V   + A   CR  G P+P + WY  G L++  + R  
Sbjct: 1602 VTGDDMSEKSKPEIVLLPEPIRVFEGETAKYRCRVTGYPTPKVNWYLNG-LLIRKSKRFR 1660

Query: 61   LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR 111
            L   G+ +L  T  + + D+G     A N  GTA      L +   +E+FR
Sbjct: 1661 LHYDGIHYLEITDCKSY-DSGDVRVLAENPEGTA-EHTVKLEIQ-QKEDFR 1708



 Score = 42.7 bits (96), Expect = 0.059
 Identities = 30/102 (29%), Positives = 45/102 (44%), Gaps = 8/102 (7%)

Query: 293  PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
            P I L P  + V  G  A++ C  TG P P + W + G   ++     R + H    +DG
Sbjct: 1613 PEIVLLPEPIRVFEGETAKYRCRVTGYPTPKVNWYLNG---LLIRKSKRFRLH----YDG 1665

Query: 353  VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394
            +  L I D    DS +  V  A N  G++    KL +   +D
Sbjct: 1666 IHYLEITDCKSYDSGDVRVL-AENPEGTAEHTVKLEIQQKED 1706



 Score = 42.7 bits (96), Expect = 0.059
 Identities = 33/121 (27%), Positives = 51/121 (42%), Gaps = 12/121 (9%)

Query: 481   ALLVDSPINPNIHFFRAADVSSL--PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGY 538
             A  +   +N +       DV+ L  PGPP       +T+ S  L+W+     G S +  Y
Sbjct: 13474 ATYIIEAVNSSGRATATVDVNILDKPGPPAAFDISEITNESCVLAWNPPRDDGGSKVTNY 13533

Query: 539   QVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
              VE   R+ +       +S  W  ++  V QT Y    L+    Y+F V  EN  G+  P
Sbjct: 13534 IVE---RKAV-------DSEIWYKLSSTVKQTTYKATKLVAFKEYIFRVYAENQFGIGAP 13583

Query: 599   S 599
             +
Sbjct: 13584 A 13584



 Score = 42.7 bits (96), Expect = 0.059
 Identities = 32/107 (29%), Positives = 44/107 (41%), Gaps = 12/107 (11%)

Query: 506   PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565
             PP KP   NVT  SVTL W+     G   + GY VE                + W+    
Sbjct: 19912 PPGKPDVINVTRNSVTLMWTAPKYDGGHKLTGYMVEKLEHP----------GKTWMKANH 19961

Query: 566   -RVHQTHYVVKSLIPGITYMFIVRTENSHG-LSGPSPVSDSVTVGDD 610
               V    Y V  L  G T  F +R +N+ G +S PS  ++ +   D+
Sbjct: 19962 VNVQSCAYTVTDLQEGCTCEFRIRAKNAAGAISAPSETTEPLVCKDE 20008



 Score = 42.3 bits (95), Expect = 0.078
 Identities = 51/213 (23%), Positives = 73/213 (34%), Gaps = 20/213 (9%)

Query: 20   DVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS 78
            D T    + A   C      P   + WYKG   + S     I   G    L+    +   
Sbjct: 7816 DQTTTVKKEAVFECEIKINYPEITLSWYKGTQKLDSGDKYDIKIVGDRHILKIKDCQTR- 7874

Query: 79   DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
            D G Y         +A+       + VL  E     +     +G T  L C      P  
Sbjct: 7875 DEGNYRIVCGPHISSAK-------LTVLEAEVEKPMQDVAGKEGQTCTLTC--QLSVPNV 7925

Query: 139  NVYWKKNGQTLLFDGDSRMHLVDGG---NLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195
               W +NG+  L +  SR           L I+D R  D G Y C  +N   T    I  
Sbjct: 7926 KTQWFRNGK--LLEPHSRYTCAVANYTQKLSIKDVRPEDQGEYTCKYKNLETTANLWIEA 7983

Query: 196  LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228
             +IH    +    +++V +   S TF+C V  D
Sbjct: 7984 EQIHFTKRI----QNIVVREHQSATFECEVSFD 8012



 Score = 42.3 bits (95), Expect = 0.078
 Identities = 41/163 (25%), Positives = 72/163 (44%), Gaps = 15/163 (9%)

Query: 122   GDTVVLECLPPRGSPEPNVY-WKKNGQTLLFDGDSRMHLVDGGNLVIQ--DARQTDAGRY 178
             G + V EC   + SP   +  W K+G  L  +        DG +  +Q  D + +D G Y
Sbjct: 10835 GSSAVFEC---QISPSTAITTWMKDGSNLR-ESPKHKFTSDGKDRKLQIIDVQLSDTGEY 10890

Query: 179   QCIAR--NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
              C+A+  N   T  + +   ++ +K +  T  E++    G  +   C +  D   DV+W+
Sbjct: 10891 TCVAKLGNKEKTSTAKLIVEELPVK-FTKTLEEEMSVIKGQPMYLTCELSKD--RDVVWK 10947

Query: 237   RSAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAEN 276
             ++        G+V+V   G   S  + +    D G Y+CE E+
Sbjct: 10948 KNGKELKQIAGKVQVNVIGLQRSATIQDTNDDDAGVYTCECED 10990



 Score = 42.3 bits (95), Expect = 0.078
 Identities = 49/186 (26%), Positives = 68/186 (36%), Gaps = 29/186 (15%)

Query: 425   PEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
             P P   W F   AL    R ++    T   LV+    ++D GTY+    +          
Sbjct: 13137 PIPTAKWTFGENALTAGDRVSMVTKSTFTELVITPSVRADKGTYSLTLEN--------DV 13188

Query: 482   LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541
               V   I  N+       ++S P  P       VT   V L W      G S I GYQVE
Sbjct: 13189 ASVSGEIEVNV-------IAS-PSAPKDLKVAEVTRKHVHLMWEAPEHDGGSPITGYQVE 13240

Query: 542   VFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPV 601
                RE         + + WV +   +    Y V  ++ G  Y+F V   N  G   P+ +
Sbjct: 13241 --KREV--------SRKTWVKVMSGLQDQEYTVTDVVEGKEYLFRVIACNKCGPGEPAYI 13290

Query: 602   SDSVTV 607
              D V V
Sbjct: 13291 EDPVNV 13296



 Score = 42.3 bits (95), Expect = 0.078
 Identities = 43/156 (27%), Positives = 67/156 (42%), Gaps = 11/156 (7%)

Query: 165   LVIQDARQTDAGRYQCIARNAAG---TRES-AIATLKIHIKPYLITGPEDVVAQTGSSVT 220
             +V+   ++    R++  ARNA G    RE+  I  +K  +    I   + V A+ GS + 
Sbjct: 18528 IVVAGLKENTKYRFRVAARNAIGCSLAREAEGIFEVKEQLMAPKIIVSDVVTARAGSKLI 18587

Query: 221   FQCRVGGDPLPDVLWRRSAGGGNMPLGRV---KVLDDGSLRLDNVILADEGEYSCEAENS 277
                 V G P P   W+R +    +   RV   K      L + +V   D G YS  AENS
Sbjct: 18588 VDALVSGKPAPVTKWKRGS-DDIVTSDRVVIQKTPTTSLLMVKDVTRKDSGYYSLSAENS 18646

Query: 278   VGAVSASGYLTVYD---PPSINLSPNSVNVESGNVA 310
                V+    + + D   PP   L    V+V++  +A
Sbjct: 18647 TAKVNQIIRIIIMDIPGPPQGPLQILEVDVDACTLA 18682



 Score = 42.3 bits (95), Expect = 0.078
 Identities = 47/182 (25%), Positives = 66/182 (36%), Gaps = 27/182 (14%)

Query: 425   PEPIIAWYFEGEALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
             P P + WY E   L      + T   TLV + +  + D+G Y     +  GK   +G + 
Sbjct: 20440 PAPEVVWYKENVPLKGRAHIDTTESYTLVVIPECTRYDAGKYVLTLENVAGKK--TGFVN 20497

Query: 484   VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543
             V           R  D    PGPP       +T  S+TL W      G S I  Y +E  
Sbjct: 20498 V-----------RVVDT---PGPPVNLKPREITKHSITLQWEIPLIDGGSKIKNYIIE-- 20541

Query: 544   SRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
              RE           + + VI     +  Y +  L     Y F V  EN  G+  P+   D
Sbjct: 20542 KREA--------TRKAYSVITTNWQKCSYKIPDLEEAAEYYFRVSAENEMGIGEPAETPD 20593

Query: 604   SV 605
              +
Sbjct: 20594 PI 20595



 Score = 42.3 bits (95), Expect = 0.078
 Identities = 31/106 (29%), Positives = 52/106 (49%), Gaps = 7/106 (6%)

Query: 106   LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN- 164
             +   F+L   +     G+ + +E +P +G P P + W K+GQ L     +R+++      
Sbjct: 23945 IEPSFKLTFNTYSVQSGEDLKVE-IPFKGRPTPKIGWMKDGQAL--KETTRLNVSSTATS 24001

Query: 165   --LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208
               L I++A + D+G+Y   A N  GT    +A + I  KP   TGP
Sbjct: 24002 TVLKIKEANREDSGKYTITATNNIGTVTEEVAII-ILDKPGPPTGP 24046



 Score = 42.3 bits (95), Expect = 0.078
 Identities = 37/162 (22%), Positives = 60/162 (37%), Gaps = 14/162 (8%)

Query: 444   RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSL 503
             +N++ D    +++ + S +     V     GKY+    L +++ +        +  V   
Sbjct: 26945 KNISGDARYAIRNTEYSTTLIIPKVTRDDTGKYL----LEIENGVGEPKTITVSVKVLDT 27000

Query: 504   PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
             P    + I  NVT   +TLSW      G S I  Y VE                + + ++
Sbjct: 27001 PSACNRLIVKNVTRGKLTLSWEPPYIDGGSPITNYVVE----------KKDAKMKAFTIV 27050

Query: 564   ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605
                   T Y V  L   I+Y F V  EN +G+  P      V
Sbjct: 27051 TNECANTTYKVDGLSEEISYFFRVSAENEYGVGDPCETEQPV 27092



 Score = 42.3 bits (95), Expect = 0.078
 Identities = 39/142 (27%), Positives = 66/142 (46%), Gaps = 20/142 (14%)

Query: 299   PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP---GMSRDKYHATAVFDGV-- 353
             P+S+ V  G+ ARF C   G P PT+ W  EG RT++      +S  +Y +T     V  
Sbjct: 32143 PHSLIVSEGDSARFVCDIDGEPAPTVTWMHEG-RTVVSSHRIHVSTTQYKSTLEISSVEY 32201

Query: 354   ------TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407
                   TV+  N   K ++R T+   A+N      ++ ++T T      P + +  P  +
Sbjct: 32202 SDEGNYTVVVENSEGKQEARCTL---AIN---KPILKEEVTPTQVKSPEPSVASPVPPIK 32255

Query: 408   TLPIKSMAVFPCTAICTPEPII 429
             + P +S    P  ++ +PEP +
Sbjct: 32256 S-P-ESSVTSPVPSVKSPEPSV 32275



 Score = 41.9 bits (94), Expect = 0.10
 Identities = 52/195 (26%), Positives = 68/195 (34%), Gaps = 27/195 (13%)

Query: 216  GSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCE 273
            G SV F   V G P P V W  +      +     V+  D+ SL +  V    EGEYSC 
Sbjct: 3418 GESVRFTVTVSGFPKPKVQWFHNGKAITSSSIYTFVEERDEYSLIITKVKKDYEGEYSCT 3477

Query: 274  AENSVGAVSASGYLTVY-------------------DPPSINLSPNSVNVESGNVARFTC 314
            A N  G  +    L V                     PP        V    G+  +F  
Sbjct: 3478 ASNRFGQTTCKTILKVELSQLSAAEKWVEKMFKIPGQPPCFTTQIQPVQCVEGSEVKFQY 3537

Query: 315  TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
              TG P P + W  +GN  I     S          DG   L +++  + DS     C A
Sbjct: 3538 KVTGTPFPDVQW-FKGNSQI----KSSQTCSVVCNPDGSGFLIMSNIQQRDS-GLYTCKA 3591

Query: 375  VNYAGSSFVRGKLTV 389
            VN  G +    +L V
Sbjct: 3592 VNPFGEASCSAELIV 3606



 Score = 41.9 bits (94), Expect = 0.10
 Identities = 66/324 (20%), Positives = 120/324 (37%), Gaps = 38/324 (11%)

Query: 499   DVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558
             ++   PGPP       +   S+   W      G S IL Y +E          +  +   
Sbjct: 14567 NILDTPGPPVNFKFEEIRKNSILCKWDPPLDDGGSEILNYILE--------RKDNSKAEL 14618

Query: 559   GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGT 618
             GW+ +   +    ++V  LI G  Y+F V  EN +G     P    +T    + + ++  
Sbjct: 14619 GWITVTSILRGCKFLVPKLIEGKEYLFRVTAENKYG-----PGKPCITKPVIARNPFDPP 14673

Query: 619   GVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEY 678
                   E ++   +   V  +E  P D           N   +EG ++  R +++     
Sbjct: 14674 DAPEKPEIKDVTASSMCVTWLE--PND-----------NGSAIEGYWVEKREINSTHWAR 14720

Query: 679   EMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGK---PSNSRVAQTLDDVPDGPP 735
               +T++   +++   +  L +   Y F +        GK   PS  + AQ    +P GPP
Sbjct: 14721 VNRTMVPDLEIN---VEGLLEGLTYIFRVCAENIAGPGKFSPPSEPKTAQA-PIMPPGPP 14776

Query: 736   INIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSL 795
             I   +   +  ++ ++W PP     NG    +   V+ L V   K         H+  + 
Sbjct: 14777 IP-RIVDTSDYSIDIEWDPP---ADNGGAEVFGYHVDKL-VAGTKDWSRATERPHKTRTF 14831

Query: 796   IMTNLTSGVSYSVQIAAETIIGLG 819
              +  +  G  Y V++ A    G G
Sbjct: 14832 TVYGVREGAKYIVRVVAINCAGEG 14855



 Score = 41.5 bits (93), Expect = 0.14
 Identities = 28/104 (26%), Positives = 43/104 (41%), Gaps = 10/104 (9%)

Query: 504   PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
             PGPP       VT +S T++W   +  G + +  Y V++  RE            GW  I
Sbjct: 25913 PGPPAHIEVKEVTKSSATITWDTPDNEGGAPVKNYLVDL--REA--------TKMGWSRI 25962

Query: 564   ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
             +    +  Y V +L  G  Y F V  EN +G+  P    +   +
Sbjct: 25963 SNSCPRLTYKVTNLQEGGVYYFRVTGENEYGVGVPLETKEGTKI 26006



 Score = 41.5 bits (93), Expect = 0.14
 Identities = 79/366 (21%), Positives = 131/366 (35%), Gaps = 40/366 (10%)

Query: 258   RLDNVILADEGEYSCEAENSVGAVSASGYLTVY---DPPSINLSPNSVNVESGNVARFTC 314
             R+ N+   +E E+   AEN  G   ASG   ++   +P S   +P  V V        T 
Sbjct: 27845 RVTNLTEGNEYEFRVMAENGAGIGPASGISRLFKCREPTSAPSAPTLVKVIDSTKTSVTL 27904

Query: 315   TATGRPEPTMFWSVEGNRTII-FPGMSRDKYHATAVFDGV-TVLTINDTDKNDSRNTIVC 372
               T   +P     +E    II     S +++H       + T   + + +  +     VC
Sbjct: 27905 AWT---KPVFDGGLEIIGYIIEMCKASLEEWHRVNNQTCIQTHYRVTELESGEEYKFRVC 27961

Query: 373   SAVNYAGSSFVRGKLTVTSDDDR--PPPIITNGPSNQTLPIKSMAVFPCTAICT--PEPI 428
              AVN AG         +    DR   P I  +    QT  +K+             P P+
Sbjct: 27962 -AVNGAGKGEFSETPHIVQAVDRLTSPEIDIDADFKQTHIVKNGGTVKLHIPFRGKPVPL 28020

Query: 429   IAWY-FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
               W   +G+  +           TL +++  + D+G YT    +  G+   +        
Sbjct: 28021 ATWTKADGDLGVMVDINTTDTFSTLTIENCTRYDAGKYTLSLENNSGRKTIT-------- 28072

Query: 488   INPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRET 547
                         V   PGPP      +VT  ++TL W   +  G + +  Y VE      
Sbjct: 28073 --------LTVKVLDTPGPPGPLSFKDVTRGALTLMWDAPSNDGGARVHHYIVEKREASR 28124

Query: 548   LSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
             LS          W  ++ R  +    V +L  G+ Y F V  EN +G   P  +++ +  
Sbjct: 28125 LS----------WQEVSERCTRQILRVINLDIGVAYFFRVTAENQYGKGEPYEMTEPIIA 28174

Query: 608   GDDSNS 613
              ++  S
Sbjct: 28175 TEEPAS 28180



 Score = 41.1 bits (92), Expect = 0.18
 Identities = 33/110 (30%), Positives = 49/110 (44%), Gaps = 11/110 (10%)

Query: 500   VSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRG 559
             +S +P PP K    +VT  SV+L W +    G S I  Y+VE+ +++             
Sbjct: 22762 ISEVPQPPGKVSVVDVTRKSVSLKWEKPEHDGGSRITYYEVEMQAKD----------QDK 22811

Query: 560   WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
             W + A +V     VV +L  G  Y+F V   N  G S P  ++  V   D
Sbjct: 22812 WSLCA-QVKALDTVVTNLAQGGEYIFRVIAVNDKGKSDPRLLASPVVAKD 22860



 Score = 41.1 bits (92), Expect = 0.18
 Identities = 17/39 (43%), Positives = 27/39 (69%)

Query: 785   INTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQ 823
             +NTTV +AT   +TN+ +G+ Y  ++AAE   G+GP S+
Sbjct: 26354 VNTTVIRATHFKVTNVNAGLIYEFKVAAENAAGIGPISK 26392



 Score = 40.7 bits (91), Expect = 0.24
 Identities = 29/90 (32%), Positives = 45/90 (50%), Gaps = 7/90 (7%)

Query: 122   GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRY 178
             GD + +E +P  G P P V WKK  Q L      R+++ +  +   L I + ++ D G+Y
Sbjct: 20716 GDNLKVE-IPVLGRPRPLVVWKKEDQEL--KQTQRINIENTASSTILNINEIKRKDGGQY 20772

Query: 179   QCIARNAAGTRESAIATLKIHIKPYLITGP 208
                 +N  GT    I T+++H  P   TGP
Sbjct: 20773 SMTGKNILGTVTENI-TVQVHDIPGPPTGP 20801



 Score = 40.7 bits (91), Expect = 0.24
 Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 1/59 (1%)

Query: 484   VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEV 542
             V  P  P + +++A D +  PG PT     + T  SVT++WS+    G   I GY VE+
Sbjct: 23536 VGQPSQPTV-YYKACDPTFKPGQPTNAHLVDTTKNSVTVAWSRPIYDGGLDIQGYVVEI 23593



 Score = 40.7 bits (91), Expect = 0.24
 Identities = 52/202 (25%), Positives = 79/202 (39%), Gaps = 15/202 (7%)

Query: 292   PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
             PP   L   + +   G   RF  T T  PEP++ W   G+R  I P     KY  T+   
Sbjct: 31321 PPEFTLPLFNRSAYIGEDVRFGVTITVHPEPSVTWLKAGHR--IKP--DPKKYTFTS-DK 31375

Query: 352   GVTVLTINDTD-KNDSRNTIVCSAVNYAGSSFVRGKLTVTSD---DDRPPPIITNGPSNQ 407
             G+  L I++ D  +D+  T+V  A N  G    + +L V      +D   P+     +N 
Sbjct: 31376 GLYQLMIHNVDLSDDAEYTVV--ANNKFGEDSCKARLNVAPHAVAEDTMRPMFKRLLANI 31433

Query: 408   TLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT----LVLKDLDKSDSG 463
                      F      TP P + W   G+ L    +  V  +      L +++    DSG
Sbjct: 31434 DCVEGQSVRFDLRVSGTPAPTLKWEKNGKPLEFRPQVEVVQEDVDYFILHIRETLIEDSG 31493

Query: 464   TYTCVASSRHGKYVWSGALLVD 485
             TY   A++  G       L V+
Sbjct: 31494 TYRVTATNTAGSASCQATLKVE 31515



 Score = 40.7 bits (91), Expect = 0.24
 Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 4/92 (4%)

Query: 27    QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
             Q    + R  G+P+P ++W K G  +       ++     +F+      +  D+G Y   
Sbjct: 31439 QSVRFDLRVSGTPAPTLKWEKNGKPLEFRPQVEVVQEDVDYFILHIRETLIEDSGTYRVT 31498

Query: 87    ATNSYGTARSRNATLHVAVL---REEFRLEPE 115
             ATN+ G+A S  ATL V  L   R EF+ E E
Sbjct: 31499 ATNTAGSA-SCQATLKVERLTYTRREFKSEEE 31529



 Score = 40.3 bits (90), Expect = 0.31
 Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 1/87 (1%)

Query: 107  REEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV 166
            + E  L PE  +  +G+T    C    G P P V W  NG  +      R+H      L 
Sbjct: 1612 KPEIVLLPEPIRVFEGETAKYRCRVT-GYPTPKVNWYLNGLLIRKSKRFRLHYDGIHYLE 1670

Query: 167  IQDARQTDAGRYQCIARNAAGTRESAI 193
            I D +  D+G  + +A N  GT E  +
Sbjct: 1671 ITDCKSYDSGDVRVLAENPEGTAEHTV 1697



 Score = 40.3 bits (90), Expect = 0.31
 Identities = 51/204 (25%), Positives = 84/204 (41%), Gaps = 23/204 (11%)

Query: 297  LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR---TIIFPGMS-RDKYHA--TAV- 349
            L+P  V +  G   RFT T +G P+P + W   G     + I+  +  RD+Y    T V 
Sbjct: 3410 LTPAEVTI--GESVRFTVTVSGFPKPKVQWFHNGKAITSSSIYTFVEERDEYSLIITKVK 3467

Query: 350  --FDGVTVLTINDTDKNDSRNTIVCSAVNY--AGSSFVRGKLTVTSDDDRPPPIITNGPS 405
              ++G    T ++     +  TI+   ++   A   +V     +       PP  T    
Sbjct: 3468 KDYEGEYSCTASNRFGQTTCKTILKVELSQLSAAEKWVEKMFKIPGQ----PPCFTTQIQ 3523

Query: 406  NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR-----NVTNDGTLVLKDLDKS 460
                   S   F      TP P + W F+G + I++ +      N    G L++ ++ + 
Sbjct: 3524 PVQCVEGSEVKFQYKVTGTPFPDVQW-FKGNSQIKSSQTCSVVCNPDGSGFLIMSNIQQR 3582

Query: 461  DSGTYTCVASSRHGKYVWSGALLV 484
            DSG YTC A +  G+   S  L+V
Sbjct: 3583 DSGLYTCKAVNPFGEASCSAELIV 3606



 Score = 40.3 bits (90), Expect = 0.31
 Identities = 31/106 (29%), Positives = 43/106 (40%), Gaps = 10/106 (9%)

Query: 504   PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
             P PP   +  + +  S  L W+   + G S I  Y VE   R+           +GW  +
Sbjct: 13799 PSPPRWLLVVSSSRNSAELKWTAPERDGGSPITNYIVE--KRDV--------RRKGWQAV 13848

Query: 564   ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
                V +  Y V  L  G  Y+F V  EN+ G S    + DSV   D
Sbjct: 13849 DTTVKELKYTVTPLNEGSLYVFRVAAENAVGPSEFCELEDSVLAKD 13894



 Score = 40.3 bits (90), Expect = 0.31
 Identities = 96/480 (20%), Positives = 169/480 (35%), Gaps = 46/480 (9%)

Query: 134   GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
             G P P + W ++   L  +       +    LVI+   +   G Y   A+NA G R+ A+
Sbjct: 16218 GKPAPEIIWNRDDAELPKEAAVETTSISSA-LVIKSCLRQHQGIYTLTAKNAGGERKKAV 16276

Query: 194   ATLKIHIK-PYLITGPEDVVAQTGSSVTFQCRV--GGDPLPD-VLWRRSAGGGNMPLGRV 249
                 + +  P  +    + +      +T+      GG  + + ++ +R A          
Sbjct: 16277 IVEVLDVPGPVGLPFSGENLTNDSCKLTWYSPEDDGGSAITNYIIEKREADRRGWTSVTY 16336

Query: 250   KVLDDGSLRLDNVILADEGEYSCEAENSVGA---VSASGYLTVYDPPSINLSPNSVNVES 306
              V    ++ +  +I      +   AEN +G       +  + + DP S+   P  V V +
Sbjct: 16337 TVTRHNAV-VQGLIDGKGYFFRIAAENIIGMGPFTETAAPVVIKDPLSVPERPEDVEVTA 16395

Query: 307   GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD-KND 365
               +   + +   R       S   +  +    + +D +   A  D +          K  
Sbjct: 16396 --ITNDSISVAWRSPKYDGGSDITSYVLEVRLIGQDNFSRIAKEDKLMDRKFTHAGLKEG 16453

Query: 366   SRNTIVCSAVNYAGS---SFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
             S      SAVN  G    SF    +T   + + PP +         + +    +      
Sbjct: 16454 SSYEFRVSAVNQIGQGKPSFSTKPVTCKKEFE-PPNLDLEFRDKLVVRVGETCIIQSRYT 16512

Query: 423   CTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479
               PEP I W+   E L  N    +T   N  +L ++   +  SG Y  V  +  G     
Sbjct: 16513 GKPEPTIKWFKNDEELQANEEIALTTAKNRLSLTIEKAKRDHSGKYMVVLENSIGTR--K 16570

Query: 480   GALLVDSPINPNIHFFRAADVSSLPGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSILGY 538
             G   V+              V   P PP  P+  + +    + +SW+     G ++I  Y
Sbjct: 16571 GICTVN--------------VVDRPQPPEGPVIFDEIYRNYMVISWNPPLDDGGAAISNY 16616

Query: 539   QVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
              VE   R+T        N   W+ +     +T   V  LI G  Y+  +  +N HG+S P
Sbjct: 16617 IVE--KRDT--------NRDLWMPVTESCTRTSCKVPKLIEGREYIIRICAQNIHGISDP 16666



 Score = 40.3 bits (90), Expect = 0.31
 Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 1/84 (1%)

Query: 211   VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGE 269
             +V + G SV  +  + G P P V W +    G+ P   +    D S   L     +D G+
Sbjct: 17879 IVVKAGESVRLEAGLRGKPQPTVTWVKDKATGDNPRISIDTGHDYSKFLLTKTKRSDTGK 17938

Query: 270   YSCEAENSVGAVSASGYLTVYDPP 293
             Y   A N  G+ +A   +TV D P
Sbjct: 17939 YVVTATNPAGSFTAYANVTVLDIP 17962



 Score = 40.3 bits (90), Expect = 0.31
 Identities = 34/124 (27%), Positives = 49/124 (39%), Gaps = 10/124 (8%)

Query: 495   FRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTP 554
             F +  V   PG P      ++T   VTL W      G S I  Y ++   RE+       
Sbjct: 23742 FVSVKVLDTPGAPQNLFVKDITRNYVTLVWEPPLIDGGSKIKNYIID--KRES------- 23792

Query: 555   RNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSL 614
                +G+  I  +  +T + V  L  G  Y F V  EN  G+  P    +SV   D   S+
Sbjct: 23793 -TRQGFTNITTKCSKTSFRVGDLTEGGIYYFRVMAENEFGIGLPVETEESVKTADPPLSV 23851

Query: 615   WEGT 618
              + T
Sbjct: 23852 GKVT 23855



 Score = 40.3 bits (90), Expect = 0.31
 Identities = 30/101 (29%), Positives = 50/101 (49%), Gaps = 8/101 (7%)

Query: 211   VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILADE 267
             V  +  +++     + G P P+V W+++   G +P  R ++   GS   L +DNV   D 
Sbjct: 24752 VTVRASATLRLFVTIRGRPEPEVKWKKA--DGTLP-ERAQIEVTGSYTGLVIDNVNRFDT 24808

Query: 268   GEYSCEAENSVGAVSASGYLTVYDPPS--INLSPNSVNVES 306
             G+Y    EN++G+ SA   + V D PS  +N     V  +S
Sbjct: 24809 GKYVLTLENNIGSKSAFVNVKVLDSPSAPVNFEVKDVKRDS 24849



 Score = 40.3 bits (90), Expect = 0.31
 Identities = 24/84 (28%), Positives = 42/84 (50%), Gaps = 2/84 (2%)

Query: 211   VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG-SLRLDNVILADEGE 269
             V  + G+++     V G P P + WR++ G      G +   ++  SL ++ V   D G+
Sbjct: 29088 VCIRAGNTLRLNVTVSGRPAPVITWRKT-GIDLQSRGFIDTTENSTSLIVEKVHRYDAGK 29146

Query: 270   YSCEAENSVGAVSASGYLTVYDPP 293
             Y+ EAEN  G  + +  + +YD P
Sbjct: 29147 YTIEAENPSGKKTITILVKIYDTP 29170



 Score = 40.3 bits (90), Expect = 0.31
 Identities = 35/128 (27%), Positives = 54/128 (42%), Gaps = 6/128 (4%)

Query: 14    IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
             I+ +P  + V+    A   C   G P+P + W   G  VVS +HR  +            
Sbjct: 32139 ILTKPHSLIVSEGDSARFVCDIDGEPAPTVTWMHEGRTVVS-SHRIHVSTTQYKSTLEIS 32197

Query: 74    GRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP 132
                +SD G Y     NS G   +R    ++  +L+EE  + P   +S +    V   +PP
Sbjct: 32198 SVEYSDEGNYTVVVENSEGKQEARCTLAINKPILKEE--VTPTQVKSPEPS--VASPVPP 32253

Query: 133   RGSPEPNV 140
               SPE +V
Sbjct: 32254 IKSPESSV 32261



 Score = 40.3 bits (90), Expect = 0.31
 Identities = 28/88 (31%), Positives = 41/88 (46%), Gaps = 4/88 (4%)

Query: 9     GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRS---ILPAGG 65
             G AP I   P D++V   +  T+ C   G P+P I W +GG  +  +   S   I     
Sbjct: 32659 GLAPRIEALPEDISVETGKVLTVACAFSGEPAPHIEWSRGGKKLPGEEDSSRFHIETTED 32718

Query: 66    LFFLRATHGRVHSDAGVYWCEATNSYGT 93
             L  L  T G   +DAG Y  + +N +G+
Sbjct: 32719 LTTLIIT-GVKETDAGAYTLKLSNEHGS 32745



 Score = 39.9 bits (89), Expect = 0.41
 Identities = 26/78 (33%), Positives = 39/78 (50%), Gaps = 4/78 (5%)

Query: 411   IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTC 467
             I S AVF C  I     I  W  +G  L ++ +   T+DG    L + D+  SD+G YTC
Sbjct: 10834 IGSSAVFECQ-ISPSTAITTWMKDGSNLRESPKHKFTSDGKDRKLQIIDVQLSDTGEYTC 10892

Query: 468   VASSRHGKYVWSGALLVD 485
             VA   + +   +  L+V+
Sbjct: 10893 VAKLGNKEKTSTAKLIVE 10910



 Score = 39.9 bits (89), Expect = 0.41
 Identities = 30/96 (31%), Positives = 41/96 (42%), Gaps = 11/96 (11%)

Query: 504   PGPPTKPIT-HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
             PG P  PI    V    + LSW+     G S I  Y VE   RE         N + WV 
Sbjct: 15990 PGVPVGPIKIGEVFAERIGLSWNPPADDGGSKITNYVVE--KRE--------ENRKTWVH 16039

Query: 563   IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
             ++    +  Y+V+ L  G  Y F V  +N +G+  P
Sbjct: 16040 VSSDPKECQYIVQRLTEGHEYEFRVMAQNKYGVGPP 16075



 Score = 39.9 bits (89), Expect = 0.41
 Identities = 36/115 (31%), Positives = 55/115 (47%), Gaps = 15/115 (13%)

Query: 122   GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN----LVIQDARQTDAGR 177
             G++V LE    RG P+P V W K+  T    GD+    +D G+     ++   +++D G+
Sbjct: 17884 GESVRLEA-GLRGKPQPTVTWVKDKAT----GDNPRISIDTGHDYSKFLLTKTKRSDTGK 17938

Query: 178   YQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
             Y   A N AG+      T   ++    I GP   +  +G S T +CRV  DP  D
Sbjct: 17939 YVVTATNPAGS-----FTAYANVTVLDIPGPVRDMKISGIS-TDKCRVAWDPPED 17987



 Score = 39.5 bits (88), Expect = 0.55
 Identities = 23/88 (26%), Positives = 39/88 (44%), Gaps = 4/88 (4%)

Query: 9    GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL--PAGGL 66
            G+ P    Q   V            +  G+P P ++W+KG   + S    S++  P G  
Sbjct: 3513 GQPPCFTTQIQPVQCVEGSEVKFQYKVTGTPFPDVQWFKGNSQIKSSQTCSVVCNPDGSG 3572

Query: 67   FFLRATHGRVHSDAGVYWCEATNSYGTA 94
            F + +   +   D+G+Y C+A N +G A
Sbjct: 3573 FLIMSNIQQ--RDSGLYTCKAVNPFGEA 3598



 Score = 39.5 bits (88), Expect = 0.55
 Identities = 33/106 (31%), Positives = 47/106 (44%), Gaps = 10/106 (9%)

Query: 506   PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565
             PP KP    V  +SVTL W+     G   I GY VE   ++ L       N R       
Sbjct: 22077 PPGKPEAVIVKRSSVTLRWTPPQFDGGIKITGYVVE---KKELP------NGRWMKASFA 22127

Query: 566   RVHQTHYVVKSLIPGITYMFIVRTENSHGLSG-PSPVSDSVTVGDD 610
              + +T +VV  L+    Y F V   N+ G+S  PS  + ++T  D+
Sbjct: 22128 NIIETEFVVSGLVEEQQYEFRVIARNAAGVSSVPSDSTGAITAKDE 22173



 Score = 39.5 bits (88), Expect = 0.55
 Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 16/135 (11%)

Query: 77    HSDAGVYW---CEATNSYGTARSRNATLHVAV--LREEFRLEPESKQSAQ-----GDTVV 126
             H   GVY+     A N  GT RS      V    + EE  ++ +   S Q     G  V 
Sbjct: 26866 HLKPGVYYYYRVSAVNCVGTGRSIEIVQPVQAKDILEEADVDLDISMSTQYIAKAGRDVE 26925

Query: 127   LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD---GGNLVIQDARQTDAGRYQCIAR 183
             +  +P +G P PNV W+K  + +   GD+R  + +      L+I    + D G+Y     
Sbjct: 26926 I-VIPLKGRPAPNVTWRKGDKNI--SGDARYAIRNTEYSTTLIIPKVTRDDTGKYLLEIE 26982

Query: 184   NAAGTRESAIATLKI 198
             N  G  ++   ++K+
Sbjct: 26983 NGVGEPKTITVSVKV 26997



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 2/86 (2%)

Query: 211   VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGE 269
             +  + G S+     + G P P+V W ++ G  N    ++ +     SL ++NV   D G+
Sbjct: 22588 ITVRAGGSLRLFVPIRGRPTPEVKWGKTEGEIN-EAAQIDITSSFTSLVIENVNRFDSGK 22646

Query: 270   YSCEAENSVGAVSASGYLTVYDPPSI 295
             Y+   EN+ G  SA   + V D P +
Sbjct: 22647 YTLTLENASGTKSAFISVRVLDTPDM 22672



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 34/107 (31%), Positives = 46/107 (42%), Gaps = 12/107 (11%)

Query: 506   PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIA- 564
             PP  P+   VT  SV L W+     G S + GY VE   R+   G         W+  + 
Sbjct: 23158 PPGTPVPVIVTRHSVKLRWTPPEYDGGSLVTGYVVE--KRDLPEGR--------WMKASF 23207

Query: 565   RRVHQTHYVVKSLIPGITYMFIVRTENSHG-LSGPSPVSDSVTVGDD 610
               + +T + V  LI    Y F V   N  G +S PS  + SVT  D+
Sbjct: 23208 ANILETEFTVTGLIEDCKYDFRVIARNGAGSVSRPSESTGSVTAKDE 23254



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 31/104 (29%), Positives = 46/104 (44%), Gaps = 8/104 (7%)

Query: 104   AVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-- 161
             A L  +   +P S   ++GD+    C    G P P V W   G+T++     R+H+    
Sbjct: 32133 ATLSAKILTKPHSLIVSEGDSARFVC-DIDGEPAPTVTWMHEGRTVV--SSHRIHVSTTQ 32189

Query: 162   -GGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL 204
                 L I     +D G Y  +  N+ G +E A  TL I+ KP L
Sbjct: 32190 YKSTLEISSVEYSDEGNYTVVVENSEGKQE-ARCTLAIN-KPIL 32231



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 53/225 (23%), Positives = 84/225 (37%), Gaps = 33/225 (14%)

Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW-----SVEGN------------RTI 334
           PP++     +V V  G      C  +G P P + W      +E +            R +
Sbjct: 741 PPTLIAGLKNVTVTEGESVTLECQISGHPTPAIMWFREDYRIENSIDFQITYEKSYARLM 800

Query: 335 IFPGMSRD--KYHATAVFDGVTVLT-----INDTDKNDSRNTIVCS---AVNYAGSSFVR 384
           I    + D  ++  TA  +  T+ T     +  +++ +SR  I       V  A    + 
Sbjct: 801 IREAFAEDSGRFTCTATSEAGTISTSCYLLVKVSEEIESREEITIQEKQTVVEAKDETMS 860

Query: 385 GKLTVTSDDDRPP-PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR 443
              +V+ D   P  P     P  Q L      VF C    +P+P I W   G  L   +R
Sbjct: 861 EISSVSVDTGAPAAPFFVKKPVVQKLVEGGSVVFVCQIGGSPKPHIYWKKSGVPLTTGYR 920

Query: 444 RNV-----TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
             V     T +  L +      D+G YT  A ++HG+   S +LL
Sbjct: 921 YRVSHNKDTGECKLEISMTFADDAGEYTIFAKNQHGETSASTSLL 965



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 2/97 (2%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P +I    +VTV   +  TL C+  G P+PAI W++    + +     I        L  
Sbjct: 742 PTLIAGLKNVTVTEGESVTLECQISGHPTPAIMWFREDYRIENSIDFQITYEKSYARLMI 801

Query: 72  THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE 108
                  D+G + C AT+  GT  S +  L V V  E
Sbjct: 802 REA-FAEDSGRFTCTATSEAGTI-STSCYLLVKVSEE 836



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 39/153 (25%), Positives = 69/153 (45%), Gaps = 8/153 (5%)

Query: 665   FIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVA 724
             ++ F+  +++  +   KT L    V    +T L +  +YEF +I       GKPS +  +
Sbjct: 19847 YVEFKDRNSLMWKRASKTQLR---VKECRVTGLVEGLEYEFRVIAINVAGLGKPSRTTES 19903

Query: 725   QTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVA 784
                 D P  PP   ++  +   +V L W+ P+       +TGY  +V  L+ P    M A
Sbjct: 19904 LVALD-PIDPPGKPDVINVTRNSVTLMWTAPKYD-GGHKLTGY--MVEKLEHPGKTWMKA 19959

Query: 785   INTTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817
              +  V Q+ +  +T+L  G +   +I A+   G
Sbjct: 19960 NHVNV-QSCAYTVTDLQEGCTCEFRIRAKNAAG 19991



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 2/83 (2%)

Query: 134   GSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
             G P P+V+W K+G+ L       +   D    L +++A + D G+Y  + +N  G  +S 
Sbjct: 22205 GKPIPSVHWIKSGEELTNTARLEIKNTDFTTTLSVKEAIRVDGGQYTLLLKNVGG-EKSV 22263

Query: 193   IATLKIHIKPYLITGPEDVVAQT 215
             I  +K+  +P    GP  +   T
Sbjct: 22264 IINVKVLDRPGPPDGPISIYGVT 22286



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 27/96 (28%), Positives = 41/96 (42%), Gaps = 9/96 (9%)

Query: 504   PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
             PGPP      N++  S+T+ W++    G + I+GY VE   R  +      +        
Sbjct: 23454 PGPPQDLEITNISRDSMTVCWTRPESDGGNEIVGYIVEKRDRAGIRWTKCNK-------- 23505

Query: 564   ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
              RRV    + V  L     Y F +  EN+ G+  PS
Sbjct: 23506 -RRVTDLRFRVTGLTEDHEYEFRLSAENAAGVGQPS 23540



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 39/132 (29%), Positives = 60/132 (45%), Gaps = 16/132 (12%)

Query: 733   GPPIN-IEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQ 791
             GP +  +EM  +   +V LKW PP        IT Y +V+      AN   + +++ V +
Sbjct: 26206 GPAVGPVEMCDITEDSVSLKWLPPAYD-GGSPITNY-IVLKRETTTAN--WIEVSSAVAR 26261

Query: 792   ATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDL---LSRYPMNGEV 848
              T  IM  L +GV Y  +I AE   G+         +IDS++V + L   L   P    V
Sbjct: 26262 CTIKIM-KLNTGVEYQFRIKAENRFGISE-------HIDSQTVTVSLPYTLPVAPSQPWV 26313

Query: 849   SIVAGDFVMETW 860
             S V  + ++  W
Sbjct: 26314 SAVTKESIVVNW 26325



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 35/136 (25%), Positives = 60/136 (44%), Gaps = 9/136 (6%)

Query: 692   FEITSLRKYTKYEFFLIPFYKKFEGKPSNSR-VAQTLDDVPDGPPINIEMFILNTTTVHL 750
             F+I +L K T+Y+F +    K     P  S  V       P GPP    +F + +  + +
Sbjct: 27351 FKIPNLVKGTEYQFRVRAENKYGVSDPLTSPDVVAQHQYKPPGPPGKPVVFNVTSDGMTV 27410

Query: 751   KWSPPELQLQNGIITGYNVVVNWLDVPANKSMV--AINTTVHQATSLIMTNLTSGVSYSV 808
             +W  P        ITGY+     L+     S++   +NT+V       +  L  G+ YS 
Sbjct: 27411 QWDAPGFD-GGSPITGYH-----LEKKDRNSLLWMKVNTSVISGREYRVIGLIEGLEYSF 27464

Query: 809   QIAAETIIGLGPFSQK 824
             ++ A+   G+ P S++
Sbjct: 27465 RVYAQNNAGMSPVSEQ 27480



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 3/91 (3%)

Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LV 453
           PP +  G  N T+         C     P P I W+ E   +  +    +T + +   L+
Sbjct: 741 PPTLIAGLKNVTVTEGESVTLECQISGHPTPAIMWFREDYRIENSIDFQITYEKSYARLM 800

Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
           +++    DSG +TC A+S  G    S  LLV
Sbjct: 801 IREAFAEDSGRFTCTATSEAGTISTSCYLLV 831



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 30/110 (27%), Positives = 43/110 (39%), Gaps = 13/110 (11%)

Query: 502   SLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV 561
             ++PGPP  P   + + T   L W +  K G S +LGY VE             +    W 
Sbjct: 17471 TVPGPPVNPKVKDYSCTYADLVWIKPTKDGGSPVLGYIVE-----------CQKGGAEWE 17519

Query: 562   VIAR--RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
              + +   + Q  Y VK L     Y F V+  N  G      + +SV   D
Sbjct: 17520 KVNKDDLIKQCAYRVKGLTEDTEYRFRVKAVNMIGEGETREIPESVIAKD 17569



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 36/139 (25%), Positives = 63/139 (45%), Gaps = 7/139 (5%)

Query: 87    ATNSYGTARSRNATLHV----AVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW 142
             ATN  G +  R  ++ V     V+   F+L   +     GD + ++ +P    P+  V W
Sbjct: 21759 ATNEKGISDPRPLSVPVIAKDVVIAPAFKLLFSTFSVLAGDDLKID-VPYVAQPKAAVVW 21817

Query: 143   KKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201
             +K+G +L         + +    L++++A + D G+Y     N+AG   + I  + +  K
Sbjct: 21818 QKDGISLKETTRVNTEVAERHLYLLLKEATRDDVGKYTIKITNSAGEATADINVIVLD-K 21876

Query: 202   PYLITGPEDVVAQTGSSVT 220
             P   TGP  +   T  SVT
Sbjct: 21877 PGPPTGPIKIEEVTADSVT 21895



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 27/102 (26%), Positives = 49/102 (48%), Gaps = 3/102 (2%)

Query: 122   GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQC 180
             G  + +E +P  G P P V   K+GQ L         +     ++ ++++  +DAGRY  
Sbjct: 26126 GSNLKIE-IPLTGKPLPKVSLSKDGQVLKSTMRFNFDVTTDSLIIYLRESVASDAGRYDI 26184

Query: 181   IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQ 222
              A N+ GT +S +  + +  +P    GP ++   T  SV+ +
Sbjct: 26185 TASNSNGTTKSFVNVVVLD-RPGPAVGPVEMCDITEDSVSLK 26225



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 10/105 (9%)

Query: 506   PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565
             PP      ++T  S++L+W + +  G S I GY +E+  ++   G  +  N         
Sbjct: 26405 PPNSVRVTDITKNSISLAWQKPSYDGGSKITGYLIEM--KDGPKGRWSKAN-------LT 26455

Query: 566   RVHQTHYVVKSLIPGITYMFIVRTENSHG-LSGPSPVSDSVTVGD 609
              V  T + V  L    +Y F V  +N+ G +S PS +   VT  D
Sbjct: 26456 NVTDTKFTVSGLTQNESYEFRVMAKNAVGSVSNPSEIVGPVTCVD 26500



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 26/85 (30%), Positives = 40/85 (47%), Gaps = 4/85 (4%)

Query: 111   RLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGD--SRMHLVDGGNLVIQ 168
             +L  E+     G  +VL+     G PEP V+W K G   L  G+  S  +       +I+
Sbjct: 28683 KLVGETISIRAGSDLVLDAAVG-GKPEPKVFWAK-GDKELDPGEKYSLTYTSTRAMAIIK 28740

Query: 169   DARQTDAGRYQCIARNAAGTRESAI 193
                + D GRY    +NA+G + SA+
Sbjct: 28741 SCDRNDTGRYILTVKNASGIKTSAV 28765



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 25/97 (25%), Positives = 45/97 (46%), Gaps = 9/97 (9%)

Query: 200   IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP------LGRVKVLD 253
             + P +   PED+  +TG  +T  C   G+P P + W R  GG  +P         ++  +
Sbjct: 32660 LAPRIEALPEDISVETGKVLTVACAFSGEPAPHIEWSR--GGKKLPGEEDSSRFHIETTE 32717

Query: 254   D-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
             D  +L +  V   D G Y+ +  N  G+  A+  +++
Sbjct: 32718 DLTTLIITGVKETDAGAYTLKLSNEHGSDLATVTISI 32754



 Score = 37.5 bits (83), Expect = 2.2
 Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 2/70 (2%)

Query: 134   GSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
             G P P V WKK+G  L L +G      V   +L +    + ++G Y   A N +G++ SA
Sbjct: 18990 GKPMPKVVWKKDGAPLKLAEGMKMTQKVHHLSLELFSVTRKESGEYTITAENPSGSK-SA 19048

Query: 193   IATLKIHIKP 202
                LK+  KP
Sbjct: 19049 NIKLKVLDKP 19058



 Score = 37.5 bits (83), Expect = 2.2
 Identities = 17/46 (36%), Positives = 26/46 (56%)

Query: 497   AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEV 542
             A D    PG P  P   + T TSV+L+WS   + G +++ GY +E+
Sbjct: 29659 AMDPIEPPGIPLNPRVTDTTRTSVSLAWSPPEEEGGAAVTGYLIEM 29704



 Score = 37.1 bits (82), Expect = 2.9
 Identities = 40/150 (26%), Positives = 60/150 (40%), Gaps = 11/150 (7%)

Query: 712   KKFEGKPSNSRVAQTLD-DVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVV 770
             K   G+   + + + LD   P G P + E   L   +  L W  PE       IT Y + 
Sbjct: 16266 KNAGGERKKAVIVEVLDVPGPVGLPFSGEN--LTNDSCKLTWYSPEDD-GGSAITNYIIE 16322

Query: 771   VNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNID 830
                 D     S V    T H A   ++  L  G  Y  +IAAE IIG+GPF++     + 
Sbjct: 16323 KREADRRGWTS-VTYTVTRHNA---VVQGLIDGKGYFFRIAAENIIGMGPFTETAAPVVI 16378

Query: 831   SRSVGLDLLSRYPMNGEVSIVAGDFVMETW 860
                +    +   P + EV+ +  D +   W
Sbjct: 16379 KDPLS---VPERPEDVEVTAITNDSISVAW 16405



 Score = 37.1 bits (82), Expect = 2.9
 Identities = 31/134 (23%), Positives = 53/134 (39%), Gaps = 7/134 (5%)

Query: 191   SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250
             S +    + I+P + T       Q G  +  + R+ G P P + W +  G       RV 
Sbjct: 22854 SPVVAKDLAIEPTVRTKLSTYSVQVGYDLKIEARISGHPKPTITWNKD-GSALKQTTRVN 22912

Query: 251   VLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP---NSVNV 304
             V D     +L + +    D G Y+    N +G   A+  + + + P     P   + V+ 
Sbjct: 22913 VADTAHHTTLTIKDATREDGGMYNIVVANVLGQQEATVEIIILEKPGPPTGPVRIDEVSA 22972

Query: 305   ESGNVARFTCTATG 318
             ES  ++    T TG
Sbjct: 22973 ESITLSWDPPTYTG 22986



 Score = 37.1 bits (82), Expect = 2.9
 Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 5/75 (6%)

Query: 293   PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPG-MSRDKYHATAVFD 351
             P I   P  ++VE+G V    C  +G P P + WS  G +    PG     ++H     D
Sbjct: 32662 PRIEALPEDISVETGKVLTVACAFSGEPAPHIEWSRGGKK---LPGEEDSSRFHIETTED 32718

Query: 352   GVTVLTINDTDKNDS 366
              +T L I    + D+
Sbjct: 32719 -LTTLIITGVKETDA 32732



 Score = 36.7 bits (81), Expect = 3.9
 Identities = 31/142 (21%), Positives = 53/142 (37%), Gaps = 8/142 (5%)

Query: 160   VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI--------TGPEDV 211
             + G   V+   ++    R++  A NAAG  E       I +K   I        T  E +
Sbjct: 16143 IRGTKFVVPGLKELGLYRFRVRAVNAAGVGEPGEVADVIEVKDRTIPPEVDLDATVKEKI 16202

Query: 212   VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYS 271
             V   G  +     V G P P+++W R                  +L + + +   +G Y+
Sbjct: 16203 VVHAGGVIRILAYVSGKPAPEIIWNRDDAELPKEAAVETTSISSALVIKSCLRQHQGIYT 16262

Query: 272   CEAENSVGAVSASGYLTVYDPP 293
               A+N+ G    +  + V D P
Sbjct: 16263 LTAKNAGGERKKAVIVEVLDVP 16284



 Score = 36.7 bits (81), Expect = 3.9
 Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 9/96 (9%)

Query: 499   DVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558
             D +  P PP+ P   + T  S++++W++    G S + GY VE+    T          +
Sbjct: 28970 DPTYTPAPPSVPRITDTTKHSISMTWTRPMYDGGSDVTGYIVEILEEGT---------EQ 29020

Query: 559   GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHG 594
              +    + +  T Y V  L     Y F V   N+ G
Sbjct: 29021 WYRATQKTLTSTQYTVTGLASNKKYSFRVAAVNAMG 29056



 Score = 36.7 bits (81), Expect = 3.9
 Identities = 28/109 (25%), Positives = 46/109 (42%), Gaps = 11/109 (10%)

Query: 500   VSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRG 559
             V  +P  P      + T ++V L W +    G S + G+ +E           T R    
Sbjct: 29263 VCEVPSVPQDLYLIDTTKSTVILGWEKPLHDGGSRLSGFVIEACK------TGTDR---- 29312

Query: 560   WVVIAR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
             W+ +A  +     + + SL     Y+F +R ENS G+S P  +   VT+
Sbjct: 29313 WMNVAHVKSSVLQHTIVSLTENEQYLFRIRAENSRGVSEPRDLMTPVTI 29361



 Score = 36.3 bits (80), Expect = 5.1
 Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 2/69 (2%)

Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQ 179
           +G++V LEC    G P P + W +    +    D ++        L+I++A   D+GR+ 
Sbjct: 755 EGESVTLEC-QISGHPTPAIMWFREDYRIENSIDFQITYEKSYARLMIREAFAEDSGRFT 813

Query: 180 CIARNAAGT 188
           C A + AGT
Sbjct: 814 CTATSEAGT 822



 Score = 36.3 bits (80), Expect = 5.1
 Identities = 29/101 (28%), Positives = 46/101 (45%), Gaps = 8/101 (7%)

Query: 717   KPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDV 776
             K S   +A+   D P G P+ +   I+   +V L+W+PPE      ++TGY  VV   D+
Sbjct: 23145 KTSEGCIARDPCD-PPGTPVPV---IVTRHSVKLRWTPPEYD-GGSLVTGY--VVEKRDL 23197

Query: 777   PANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817
             P  + M A    + + T   +T L     Y  ++ A    G
Sbjct: 23198 PEGRWMKASFANILE-TEFTVTGLIEDCKYDFRVIARNGAG 23237



 Score = 36.3 bits (80), Expect = 5.1
 Identities = 37/140 (26%), Positives = 61/140 (43%), Gaps = 12/140 (8%)

Query: 688   DVSGFEITSLRKYTKYEFFLIPFYKKFEGKP--SNSRVAQTLDDVPDGPPINIEMFILNT 745
             +   F  T L K  +Y+F +    K   GKP  S+  +AQ    VPD P    +   +  
Sbjct: 27739 EACSFNATKLIKGNEYQFRVSAVNKFGVGKPLESDPIIAQMQYTVPDAPGTP-DCTHVTG 27797

Query: 746   TTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLI---MTNLTS 802
              ++ L W+ P     +G   G  +    L+    KS+  +  +  +  + +   +TNLT 
Sbjct: 27798 NSITLCWTRPR---HDG---GNEIKQYILERREKKSLRWVKVSAKRPITELRHRVTNLTE 27851

Query: 803   GVSYSVQIAAETIIGLGPFS 822
             G  Y  ++ AE   G+GP S
Sbjct: 27852 GNEYEFRVMAENGAGIGPAS 27871



 Score = 36.3 bits (80), Expect = 5.1
 Identities = 27/104 (25%), Positives = 41/104 (39%), Gaps = 11/104 (10%)

Query: 504   PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
             P  P +    + T T+ +L W +    G S I GY VE             + S  W V 
Sbjct: 28178 PASPKRLDVIDTTSTTASLVWMKPEHDGGSRITGYIVE----------TRKKGSANW-VF 28226

Query: 564   ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
               +      V++ L+    Y F V+ +N  G+S P     SV +
Sbjct: 28227 GGQTKSLKMVLEGLVENTEYEFRVKAQNDAGISQPRDALASVII 28270



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 29/93 (31%), Positives = 38/93 (40%), Gaps = 10/93 (10%)

Query: 504   PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
             PGP       +V   S  LSW      G + I  + VE   ++  S    P+    WV I
Sbjct: 16979 PGPVQHLRVSDVRSDSAQLSWKDPEDNGGARITNFVVE--KKDAAS----PQ----WVPI 17028

Query: 564   ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
                  +   + K LI G +YMF V  EN  G S
Sbjct: 17029 CSSSKKRSMMAKHLIEGTSYMFRVAAENQFGRS 17061



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 25/96 (26%), Positives = 38/96 (39%), Gaps = 10/96 (10%)

Query: 500   VSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRG 559
             V   PGPP   I    +   V+++W      G S +  Y VE    E           + 
Sbjct: 19454 VLDTPGPPVNLIVKETSKDHVSITWDAPLIDGGSPVKSYVVEKRLAE----------RKA 19503

Query: 560   WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGL 595
             W  +A    +T + + +L  G  Y F V  EN +G+
Sbjct: 19504 WTCVAPECPKTSFRITNLEAGQAYCFRVLAENIYGI 19539



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 5/85 (5%)

Query: 733   GPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQA 792
             GPP  I++  ++   + L W PP   + +G     N VV   D       + ++ TV + 
Sbjct: 25124 GPPGAIKVEEISADFISLSWDPP---IYDGGCQINNYVVEKRDTTTTAWQI-VSATVAR- 25178

Query: 793   TSLIMTNLTSGVSYSVQIAAETIIG 817
             TS+ ++ LT G  Y  +IAAE   G
Sbjct: 25179 TSIKVSRLTQGTEYQFRIAAENRYG 25203



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 38/155 (24%), Positives = 64/155 (41%), Gaps = 17/155 (10%)

Query: 178   YQCIARNAAG-----TRESAIATLKIHIKPYLITGPED----VVAQTGSSVTFQCRVGGD 228
             ++ IA+NAAG     +  +   T+K  + P  IT  +     VV + G  +     + G 
Sbjct: 25392 FRIIAKNAAGLFSEPSESTGPVTVKDDVDPPRITIEDKLRQLVVIKAGEILRIDAEISGR 25451

Query: 229   PLPDVLWRRSAGGGNMPLGRVKV---LDDGSLRLDNVILADEGEYSCEAENSVGAVSASG 285
             P+P + W +  G       R ++   L   +L + + I  D G+Y    +N  G  S + 
Sbjct: 25452 PIPVISWAKD-GKEIEAKARFEISSTLTSTTLIVRDAIRRDSGQYVLTLQNVAGTRSLAV 25510

Query: 286   YLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
                V D P     P+S  ++   +    CT T  P
Sbjct: 25511 NCKVLDRP----GPSSGPLDITGLTAEKCTLTWGP 25541



 Score = 35.5 bits (78), Expect = 8.9
 Identities = 25/98 (25%), Positives = 40/98 (40%), Gaps = 11/98 (11%)

Query: 501   SSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGW 560
             S  P  P   I  +V+  + TL+W++    G S I GY +E             ++S  W
Sbjct: 20598 SQAPSAPDDLIVTDVSKDTATLAWTKPKHDGGSRITGYVIEA----------QLKDSDQW 20647

Query: 561   VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
               +   +    Y+   L+    Y+F +   NS G S P
Sbjct: 20648 AHVT-TIKALDYIATELVENAEYVFRIFAVNSSGRSEP 20684



 Score = 35.5 bits (78), Expect = 8.9
 Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 6/82 (7%)

Query: 16    EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGLFFLRATH 73
             E    +T+   +   L+C   G P P + WYK G  V  +     +++ +  LF   A  
Sbjct: 27596 EAEKSLTIKAGENIKLSCSISGRPVPQVTWYKDGKEVDKMLVDITTVIGSSSLFIRDA-- 27653

Query: 74    GRVHSDAGVYWCEATNSYGTAR 95
              R H   G+Y  EA NS GT +
Sbjct: 27654 DRNH--RGIYTVEAKNSSGTTK 27673



 Score = 35.5 bits (78), Expect = 8.9
 Identities = 21/81 (25%), Positives = 36/81 (44%), Gaps = 3/81 (3%)

Query: 398   PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN-DGTLVLK- 455
             P IT    +  +P      F       P+  I W+  G+ + ++H+   TN  G L L+ 
Sbjct: 31919 PRITVRMRSHRVPCGQNTKFTLNVQSKPDANIQWFHNGQQIQESHKYQFTNMSGVLSLQI 31978

Query: 456   -DLDKSDSGTYTCVASSRHGK 475
              D    D+GTY  + ++  G+
Sbjct: 31979 NDCQAEDTGTYRALCTNSKGE 31999


>UniRef50_UPI0000D576E1 Cluster: PREDICTED: similar to CG12002-PA,
           isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG12002-PA, isoform A - Tribolium castaneum
          Length = 1388

 Score =  151 bits (367), Expect = 9e-35
 Identities = 95/285 (33%), Positives = 148/285 (51%), Gaps = 17/285 (5%)

Query: 11  APYIIEQPLDVTVARHQPA-TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
           +P  +  P+ VT +   P+ +L+C+A G+P P I W + G+ + + + R  +   G   +
Sbjct: 335 SPVFLVTPVSVTTSESDPSVSLHCKAFGNPHPTITWSRNGIQLTT-SQRHFIDEDGTLVI 393

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
           R       SD G Y C+ATNS G   S  +  ++VA +   F + P++ ++  G T+ LE
Sbjct: 394 RPVKA---SDHGTYRCDATNSNGRISSEADVIVNVAPV---FTVHPQNTETTPGSTIKLE 447

Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
           C    GSP P + W K+   +  DG   +   DG +L I +A++TD+G Y C ARN  G 
Sbjct: 448 CFAV-GSPPPEITWFKDDLEVRSDGRLSIS-PDGSSLQIHNAKETDSGLYICEARNHLGF 505

Query: 189 RESAIATLKI----HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
           RE + A +K+       P  I  P ++ A  GS++   C+  GDP P + W++  G    
Sbjct: 506 REVS-AKVKVTPLARKPPKFIYKPYNIEALVGSTIELPCKADGDPTPGIQWQKD-GASLQ 563

Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
             GR KV   G+L +  V+  D+G Y C A N  G  +AS Y+TV
Sbjct: 564 RTGRTKVSLIGNLYIYGVVPDDQGRYECAAINDFGRSTASCYVTV 608



 Score =  146 bits (353), Expect = 4e-33
 Identities = 106/390 (27%), Positives = 177/390 (45%), Gaps = 28/390 (7%)

Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT 173
           P+  + + G T V  C    G P+P++YW ++ + +  + D +  ++D G+LVI+   ++
Sbjct: 240 PQDVEISWGSTAVFTCRVT-GDPKPSIYWMRDDKEIEMNND-KYDIMDNGSLVIKHTDES 297

Query: 174 DAGRYQCIARNAAGTRESAIATLKIHIKP------------YLITGPEDVVAQTGSSVTF 221
           D+G Y+C+A+N  G  +S  A + I ++P            +L+T      +++  SV+ 
Sbjct: 298 DSGHYECMAKNEDGEVKSRPARM-ILVRPDQQFRGGNGSPVFLVTPVSVTTSESDPSVSL 356

Query: 222 QCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVGA 280
            C+  G+P P + W R+  G  +   +   +D DG+L +  V  +D G Y C+A NS G 
Sbjct: 357 HCKAFGNPHPTITWSRN--GIQLTTSQRHFIDEDGTLVIRPVKASDHGTYRCDATNSNGR 414

Query: 281 VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340
           +S+   + V   P   + P +     G+  +  C A G P P + W  +           
Sbjct: 415 ISSEADVIVNVAPVFTVHPQNTETTPGSTIKLECFAVGSPPPEITWFKDDLEV------- 467

Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII 400
           R     +   DG + L I++  + DS    +C A N+ G   V  K+ VT    +PP  I
Sbjct: 468 RSDGRLSISPDGSS-LQIHNAKETDS-GLYICEARNHLGFREVSAKVKVTPLARKPPKFI 525

Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS 460
              P N    + S    PC A   P P I W  +G +L +  R  V+  G L +  +   
Sbjct: 526 YK-PYNIEALVGSTIELPCKADGDPTPGIQWQKDGASLQRTGRTKVSLIGNLYIYGVVPD 584

Query: 461 DSGTYTCVASSRHGKYVWSGALLVDSPINP 490
           D G Y C A +  G+   S  + V    NP
Sbjct: 585 DQGRYECAAINDFGRSTASCYVTVKENQNP 614



 Score =  139 bits (336), Expect = 5e-31
 Identities = 99/337 (29%), Positives = 156/337 (46%), Gaps = 25/337 (7%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
           +AP I+E P DV ++    A   CR  G P P+I W +    +  +  +  +   G   +
Sbjct: 232 KAPEIMEGPQDVEISWGSTAVFTCRVTGDPKPSIYWMRDDKEIEMNNDKYDIMDNGSLVI 291

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR---------LEPESKQSA 120
           + T     SD+G Y C A N  G  +SR A + +    ++FR         + P S  ++
Sbjct: 292 KHTD---ESDSGHYECMAKNEDGEVKSRPARMILVRPDQQFRGGNGSPVFLVTPVSVTTS 348

Query: 121 QGD-TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRY 178
           + D +V L C    G+P P + W +NG  L     S+ H +D  G LVI+  + +D G Y
Sbjct: 349 ESDPSVSLHC-KAFGNPHPTITWSRNGIQLT---TSQRHFIDEDGTLVIRPVKASDHGTY 404

Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238
           +C A N+ G R S+ A + +++ P     P++     GS++  +C   G P P++ W + 
Sbjct: 405 RCDATNSNG-RISSEADVIVNVAPVFTVHPQNTETTPGSTIKLECFAVGSPPPEITWFKD 463

Query: 239 AGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVG--AVSASGYLT--VYDPP 293
                   GR+ +  DG SL++ N    D G Y CEA N +G   VSA   +T     PP
Sbjct: 464 DLEVRSD-GRLSISPDGSSLQIHNAKETDSGLYICEARNHLGFREVSAKVKVTPLARKPP 522

Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
                P ++    G+     C A G P P + W  +G
Sbjct: 523 KFIYKPYNIEALVGSTIELPCKADGDPTPGIQWQKDG 559



 Score = 99.5 bits (237), Expect = 5e-19
 Identities = 83/296 (28%), Positives = 124/296 (41%), Gaps = 29/296 (9%)

Query: 193 IATLKIHIK-PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
           + T   H K P ++ GP+DV    GS+  F CRV GDP P + W R      M   +  +
Sbjct: 224 MTTRDFHCKAPEIMEGPQDVEISWGSTAVFTCRVTGDPKPSIYWMRDDKEIEMNNDKYDI 283

Query: 252 LDDGSLRLDNVILADEGEYSCEAENSVGAV-SASGYLTVYDP----------PSINLSPN 300
           +D+GSL + +   +D G Y C A+N  G V S    + +  P          P   ++P 
Sbjct: 284 MDNGSLVIKHTDESDSGHYECMAKNEDGEVKSRPARMILVRPDQQFRGGNGSPVFLVTPV 343

Query: 301 SVNV-ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
           SV   ES       C A G P PT+ WS  G +      ++  + H     D    L I 
Sbjct: 344 SVTTSESDPSVSLHCKAFGNPHPTITWSRNGIQ------LTTSQRH---FIDEDGTLVIR 394

Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419
               +D   T  C A N  G       + V        P+ T  P N      S     C
Sbjct: 395 PVKASD-HGTYRCDATNSNGRISSEADVIV-----NVAPVFTVHPQNTETTPGSTIKLEC 448

Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
            A+ +P P I W+ +   +  + R +++ DG +L + +  ++DSG Y C A +  G
Sbjct: 449 FAVGSPPPEITWFKDDLEVRSDGRLSISPDGSSLQIHNAKETDSGLYICEARNHLG 504



 Score = 78.6 bits (185), Expect = 1e-12
 Identities = 58/190 (30%), Positives = 89/190 (46%), Gaps = 16/190 (8%)

Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
           P I   P  V +  G+ A FTC  TG P+P+++W +  ++ I    M+ DKY    + D 
Sbjct: 234 PEIMEGPQDVEISWGSTAVFTCRVTGDPKPSIYW-MRDDKEI---EMNNDKYD---IMDN 286

Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR-GKLTVTSDDDR-----PPPIITNGPSN 406
            + L I  TD++DS +   C A N  G    R  ++ +   D +       P+    P +
Sbjct: 287 GS-LVIKHTDESDSGH-YECMAKNEDGEVKSRPARMILVRPDQQFRGGNGSPVFLVTPVS 344

Query: 407 QTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465
            T      +V   C A   P P I W   G  L  + R  +  DGTLV++ +  SD GTY
Sbjct: 345 VTTSESDPSVSLHCKAFGNPHPTITWSRNGIQLTTSQRHFIDEDGTLVIRPVKASDHGTY 404

Query: 466 TCVASSRHGK 475
            C A++ +G+
Sbjct: 405 RCDATNSNGR 414


>UniRef50_Q4RJ21 Cluster: Chromosome 1 SCAF15039, whole genome shotgun
            sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1
            SCAF15039, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 1702

 Score =  151 bits (366), Expect = 1e-34
 Identities = 144/487 (29%), Positives = 215/487 (44%), Gaps = 49/487 (10%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG-GLFFLRATHGRVHS 78
            +V++   Q  +L C   GSPSP I WYK  + VV+  +  IL  G  L  L+A      +
Sbjct: 1115 NVSLVLSQSTSLVCDVTGSPSPVITWYKEEMPVVASDNVQILDMGKTLRLLKAD----PA 1170

Query: 79   DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG-DTVV-------LECL 130
            D+G Y C+A N  G+A        VAVL     + P  K S    DTV        LEC 
Sbjct: 1171 DSGSYSCKAVNIAGSAEK---GFFVAVL-----VPPTIKGSGSSHDTVAMVTQEISLEC- 1221

Query: 131  PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTR 189
               G P P + W K+ +  +F GD  + + + G ++ I+ AR  D  RYQC   N AG +
Sbjct: 1222 KVEGLPFPTIQWYKD-RKQVFLGDPNLEVTNRGQILRIKSARLGDKARYQCSVMNTAG-K 1279

Query: 190  ESAIATLKIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
            ES    L +H+ P +  G     V A  G+ VT +C   G P P V W R+ G   +   
Sbjct: 1280 ESRDFNLSVHVPPTIKGGNASTGVTALLGTVVTLECEGRGVPPPTVTWYRN-GQAILSGR 1338

Query: 248  RVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI---NLSPNSVN 303
            + +  + G  L++  V   D G Y+C+A + VG+   +  L VY PP+I   +  P    
Sbjct: 1339 QTQYTERGRFLKILRVQATDAGRYTCKAASVVGSTEKTFELDVYLPPTIKGDDAGPTERK 1398

Query: 304  VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
            V         C A GRP P++ W        +  G+      +  V +    + I+    
Sbjct: 1399 VVLSASLILECEAGGRPPPSLTW--------LKDGVPVRHSQSLRVLELGGKIEISSATL 1450

Query: 364  NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP--SNQTLPIKSMAVFPCTA 421
            +DS    VC A + AG   V+  +TV       PP I      ++ T+ I       C A
Sbjct: 1451 SDS-GRYVCVATSVAGEKEVKYDVTVL-----VPPFIQGAGVITHSTVIINHPLEMECQA 1504

Query: 422  ICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
              TP P++ WY +G+ + Q     V   G  L++     SD+  + CVA++  G      
Sbjct: 1505 TGTPTPVVTWYKDGKPIQQGEGWRVAAGGQRLLVSRAQISDTARFQCVAANEAGDIQRDF 1564

Query: 481  ALLVDSP 487
             ++V  P
Sbjct: 1565 TVVVHEP 1571



 Score =  131 bits (316), Expect = 1e-28
 Identities = 133/476 (27%), Positives = 196/476 (41%), Gaps = 33/476 (6%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLFF 68
            E P+    PL   VA +Q     C A G P P IRW + G  L  ++   SIL  G L  
Sbjct: 1014 EPPF--NSPLQERVA-NQRIAFPCPAKGLPKPVIRWLRNGQELTGNEPGVSILEDGTLLL 1070

Query: 69   LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS-AQGDTVVL 127
            L +       D+G Y C A N  G+   R   L V V  +    E     S     +  L
Sbjct: 1071 LASVS---PLDSGEYVCAAANDAGST-ERKYQLKVNVPPDFTDNEVSRNVSLVLSQSTSL 1126

Query: 128  ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
             C    GSP P + W K    ++   D+   L  G  L +  A   D+G Y C A N AG
Sbjct: 1127 VC-DVTGSPSPVITWYKEEMPVV-ASDNVQILDMGKTLRLLKADPADSGSYSCKAVNIAG 1184

Query: 188  TRESAIATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
            + E     + + + P +       D VA     ++ +C+V G P P + W +      + 
Sbjct: 1185 SAEKGF-FVAVLVPPTIKGSGSSHDTVAMVTQEISLECKVEGLPFPTIQWYKDRKQVFLG 1243

Query: 246  LGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
               ++V + G  LR+ +  L D+  Y C   N+ G  S    L+V+ PP+I     S  V
Sbjct: 1244 DPNLEVTNRGQILRIKSARLGDKARYQCSVMNTAGKESRDFNLSVHVPPTIKGGNASTGV 1303

Query: 305  ES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
             +  G V    C   G P PT+ W   G    I  G  + +Y     F  + +L +  TD
Sbjct: 1304 TALLGTVVTLECEGRGVPPPTVTWYRNGQ--AILSG-RQTQYTERGRF--LKILRVQATD 1358

Query: 363  KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN--GPSNQTLPIKSMAVFPCT 420
                R T  C A +  GS+    + T   D   PP I  +  GP+ + + + +  +  C 
Sbjct: 1359 A--GRYT--CKAASVVGST----EKTFELDVYLPPTIKGDDAGPTERKVVLSASLILECE 1410

Query: 421  AICTPEPIIAWYFEGEALIQNHRRNVTN-DGTLVLKDLDKSDSGTYTCVASSRHGK 475
            A   P P + W  +G  +  +    V    G + +     SDSG Y CVA+S  G+
Sbjct: 1411 AGGRPPPSLTWLKDGVPVRHSQSLRVLELGGKIEISSATLSDSGRYVCVATSVAGE 1466



 Score =  131 bits (316), Expect = 1e-28
 Identities = 129/479 (26%), Positives = 194/479 (40%), Gaps = 38/479 (7%)

Query: 27   QPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85
            Q  +L C+  G P P I+WYK    V + D +  +   G +  LR    R+  D   Y C
Sbjct: 1215 QEISLECKVEGLPFPTIQWYKDRKQVFLGDPNLEVTNRGQI--LRIKSARL-GDKARYQC 1271

Query: 86   EATNSYGT-ARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK 144
               N+ G  +R  N ++HV    +          +  G  V LEC   RG P P V W +
Sbjct: 1272 SVMNTAGKESRDFNLSVHVPPTIKGGNAST-GVTALLGTVVTLEC-EGRGVPPPTVTWYR 1329

Query: 145  NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL 204
            NGQ +L  G    +   G  L I   + TDAGRY C A +  G+ E     L +++ P +
Sbjct: 1330 NGQAIL-SGRQTQYTERGRFLKILRVQATDAGRYTCKAASVVGSTEKTFE-LDVYLPPTI 1387

Query: 205  I---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLD 260
                 GP +      +S+  +C  GG P P + W +  G        ++VL+  G + + 
Sbjct: 1388 KGDDAGPTERKVVLSASLILECEAGGRPPPSLTWLKD-GVPVRHSQSLRVLELGGKIEIS 1446

Query: 261  NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVNVESGNVARFTCTATG 318
            +  L+D G Y C A +  G       +TV  PP I  +       V   +     C ATG
Sbjct: 1447 SATLSDSGRYVCVATSVAGEKEVKYDVTVLVPPFIQGAGVITHSTVIINHPLEMECQATG 1506

Query: 319  RPEPTMFWSVEGNRTIIFPG-----------MSRDKYHATAVFDGVTVLTINDTDKNDSR 367
             P P + W  +G       G           +SR +   TA F  V      D  ++ + 
Sbjct: 1507 TPTPVVTWYKDGKPIQQGEGWRVAAGGQRLLVSRAQISDTARFQCVAANEAGDIQRDFTV 1566

Query: 368  NTIVCSAVNYAGS----SFVRGKLT-----VTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
                  +V +AG     + + G  T      T      PP+I++     T+ +   A   
Sbjct: 1567 VVHEPPSVPHAGDVINQTILAGFSTQLECKATGTPLPVPPVISSQGGTVTVLVNEPARLE 1626

Query: 419  CTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGK 475
            C A   P P   W  +G  +    H   V ++G  L L     +D+GTYTCVA +  G+
Sbjct: 1627 CEATGVPSPSFTWLKDGSPVASVPHGLQVLSEGRALSLNSALVTDTGTYTCVAVNAGGE 1685



 Score =  120 bits (289), Expect = 2e-25
 Identities = 120/434 (27%), Positives = 175/434 (40%), Gaps = 37/434 (8%)

Query: 11   APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD---THRSILPAG-GL 66
            AP    +P D         TL C   G P P + W +   L   +   T+ S+  +  GL
Sbjct: 593  APEFTREPSDTASDIGSNVTLWCLVRGYPDPQVTWRRQDGLPPFNRPRTYGSVTQSRRGL 652

Query: 67   FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
             F   TH  V  +A VY CEA N +G   ++       ++       P      +   V 
Sbjct: 653  HF---THLWVEDEA-VYVCEAHNHFGKIEAKARITVTGLVLPVIARSPSVLSVVEDQPVT 708

Query: 127  LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
            L C+   G+P P   W  N    L   D  + +   G+L I+  R    G Y C+A N  
Sbjct: 709  LPCVLLAGNPLPARQWLHNYG--LVTTDQYVKVRKDGSLHIERVRLDHVGDYTCLAENVV 766

Query: 187  GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
            G       TL +++ P +  GP+      G+ VT  CR  G P P++ W +   G  + L
Sbjct: 767  GLYNHT-TTLNVYVIPTIQHGPQVFNTIEGTPVTLPCRAIGVPSPEITWTKE--GKLLYL 823

Query: 247  GRVK-VLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-------DPPSINL 297
            G     LD DGSL +++    + GE+ C A N+ G  S    LTVY       + P  + 
Sbjct: 824  GGPDFFLDSDGSLFINSPSGNESGEFICMATNAAGHASRRVQLTVYVRPRSNAEGPGSSA 883

Query: 298  SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
             P  ++V  G  A   C     P PT+ W+ E    +I P   R  +H          + 
Sbjct: 884  EPLRMSVTEGEDAILPCEVHSVPPPTITWAKE---RLISPFAPR--HHPLPSCS----MK 934

Query: 358  INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
            I ++  +DS    VC A N AG+  +   L+V       PP I  GP    + +      
Sbjct: 935  ILESKVSDS-GIYVCVASNIAGNLTLSVLLSVL-----VPPSIQPGPRVMKVQVGHPVEL 988

Query: 418  PCTAICTPEPIIAW 431
            PC     PEP + W
Sbjct: 989  PCMVSGVPEPTLTW 1002



 Score =  119 bits (287), Expect = 4e-25
 Identities = 114/385 (29%), Positives = 154/385 (40%), Gaps = 17/385 (4%)

Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LV 166
           EF  EP    S  G  V L CL  RG P+P V W++      F+       V      L 
Sbjct: 595 EFTREPSDTASDIGSNVTLWCLV-RGYPDPQVTWRRQDGLPPFNRPRTYGSVTQSRRGLH 653

Query: 167 IQDARQTDAGRYQCIARNAAGTRES-AIATLKIHIKPYLITGPEDVVAQTGSSVTFQC-R 224
                  D   Y C A N  G  E+ A  T+   + P +   P  +       VT  C  
Sbjct: 654 FTHLWVEDEAVYVCEAHNHFGKIEAKARITVTGLVLPVIARSPSVLSVVEDQPVTLPCVL 713

Query: 225 VGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSAS 284
           + G+PLP   W  + G        VKV  DGSL ++ V L   G+Y+C AEN VG  + +
Sbjct: 714 LAGNPLPARQWLHNYGLVTTDQ-YVKVRKDGSLHIERVRLDHVGDYTCLAENVVGLYNHT 772

Query: 285 GYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
             L VY  P+I   P   N   G      C A G P P + W+ EG   +++ G   D +
Sbjct: 773 TTLNVYVIPTIQHGPQVFNTIEGTPVTLPCRAIGVPSPEITWTKEGK--LLYLG-GPDFF 829

Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT--VTSDDDRPPPIITN 402
                 D    L IN    N+S    +C A N AG +  R +LT  V    +   P  + 
Sbjct: 830 -----LDSDGSLFINSPSGNES-GEFICMATNAAGHASRRVQLTVYVRPRSNAEGPGSSA 883

Query: 403 GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDS 462
            P   ++     A+ PC     P P I W  E        R +     ++ + +   SDS
Sbjct: 884 EPLRMSVTEGEDAILPCEVHSVPPPTITWAKERLISPFAPRHHPLPSCSMKILESKVSDS 943

Query: 463 GTYTCVASSRHGKYVWSGALLVDSP 487
           G Y CVAS+  G    S  L V  P
Sbjct: 944 GIYVCVASNIAGNLTLSVLLSVLVP 968



 Score =  119 bits (286), Expect = 6e-25
 Identities = 98/330 (29%), Positives = 140/330 (42%), Gaps = 18/330 (5%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNC-RAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
            VT    P I   P  ++V   QP TL C    G+P PA +W     LV +D +  +   G
Sbjct: 684  VTGLVLPVIARSPSVLSVVEDQPVTLPCVLLAGNPLPARQWLHNYGLVTTDQYVKVRKDG 743

Query: 65   GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
             L   R     V    G Y C A N  G   +   TL+V V+    +  P+   + +G  
Sbjct: 744  SLHIERVRLDHV----GDYTCLAENVVGLY-NHTTTLNVYVI-PTIQHGPQVFNTIEGTP 797

Query: 125  VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
            V L C    G P P + W K G+ LL+ G     L   G+L I      ++G + C+A N
Sbjct: 798  VTLPCRAI-GVPSPEITWTKEGK-LLYLGGPDFFLDSDGSLFINSPSGNESGEFICMATN 855

Query: 185  AAGTRESAIATLKIHIKPYL-ITGPEDVVAQTGSSVT------FQCRVGGDPLPDVLWRR 237
            AAG   S    L ++++P     GP         SVT        C V   P P + W +
Sbjct: 856  AAG-HASRRVQLTVYVRPRSNAEGPGSSAEPLRMSVTEGEDAILPCEVHSVPPPTITWAK 914

Query: 238  SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
                      R   L   S+++    ++D G Y C A N  G ++ S  L+V  PPSI  
Sbjct: 915  ERLISPFA-PRHHPLPSCSMKILESKVSDSGIYVCVASNIAGNLTLSVLLSVLVPPSIQP 973

Query: 298  SPNSVNVESGNVARFTCTATGRPEPTMFWS 327
             P  + V+ G+     C  +G PEPT+ W+
Sbjct: 974  GPRVMKVQVGHPVELPCMVSGVPEPTLTWT 1003



 Score =  116 bits (279), Expect = 4e-24
 Identities = 105/380 (27%), Positives = 161/380 (42%), Gaps = 32/380 (8%)

Query: 103  VAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG 162
            V VL   F    + + + Q   +   C P +G P+P + W +NGQ L  +      L DG
Sbjct: 1010 VEVLEPPFNSPLQERVANQ--RIAFPC-PAKGLPKPVIRWLRNGQELTGNEPGVSILEDG 1066

Query: 163  GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG--PEDVVAQTGSSVT 220
              L++      D+G Y C A N AG+ E     LK+++ P         +V      S +
Sbjct: 1067 TLLLLASVSPLDSGEYVCAAANDAGSTERKY-QLKVNVPPDFTDNEVSRNVSLVLSQSTS 1125

Query: 221  FQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDG-SLRLDNVILADEGEYSCEAEN 276
              C V G P P + W +      MP+     V++LD G +LRL     AD G YSC+A N
Sbjct: 1126 LVCDVTGSPSPVITWYKE----EMPVVASDNVQILDMGKTLRLLKADPADSGSYSCKAVN 1181

Query: 277  SVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT--CTATGRPEPTMFWSVEGNRTI 334
              G+     ++ V  PP+I  S +S +  +      +  C   G P PT+ W  +  R  
Sbjct: 1182 IAGSAEKGFFVAVLVPPTIKGSGSSHDTVAMVTQEISLECKVEGLPFPTIQWYKD--RKQ 1239

Query: 335  IFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394
            +F G          V +   +L I      D +    CS +N AG       L+V     
Sbjct: 1240 VFLGDPN-----LEVTNRGQILRIKSARLGD-KARYQCSVMNTAGKESRDFNLSV----- 1288

Query: 395  RPPPIITNGPSNQ--TLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT- 451
              PP I  G ++   T  + ++    C     P P + WY  G+A++   +   T  G  
Sbjct: 1289 HVPPTIKGGNASTGVTALLGTVVTLECEGRGVPPPTVTWYRNGQAILSGRQTQYTERGRF 1348

Query: 452  LVLKDLDKSDSGTYTCVASS 471
            L +  +  +D+G YTC A+S
Sbjct: 1349 LKILRVQATDAGRYTCKAAS 1368



 Score =  105 bits (253), Expect = 6e-21
 Identities = 84/337 (24%), Positives = 144/337 (42%), Gaps = 15/337 (4%)

Query: 21   VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
            VT       TL C   G P P + WY+ G  ++S         G   FL+    +  +DA
Sbjct: 1303 VTALLGTVVTLECEGRGVPPPTVTWYRNGQAILSGRQTQYTERGR--FLKILRVQA-TDA 1359

Query: 81   GVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
            G Y C+A +  G T ++    +++    +     P  ++     +++LEC    G P P+
Sbjct: 1360 GRYTCKAASVVGSTEKTFELDVYLPPTIKGDDAGPTERKVVLSASLILEC-EAGGRPPPS 1418

Query: 140  VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
            + W K+G  +      R+ L  GG + I  A  +D+GRY C+A + AG +E     + + 
Sbjct: 1419 LTWLKDGVPVRHSQSLRV-LELGGKIEISSATLSDSGRYVCVATSVAGEKEVKY-DVTVL 1476

Query: 200  IKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS 256
            + P+ I G   +   T      +  +C+  G P P V W +         G         
Sbjct: 1477 VPPF-IQGAGVITHSTVIINHPLEMECQATGTPTPVVTWYKDGKPIQQGEGWRVAAGGQR 1535

Query: 257  LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN--VESGNVARFTC 314
            L +    ++D   + C A N  G +     + V++PPS+  + + +N  + +G   +  C
Sbjct: 1536 LLVSRAQISDTARFQCVAANEAGDIQRDFTVVVHEPPSVPHAGDVINQTILAGFSTQLEC 1595

Query: 315  TATGR--PEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
             ATG   P P +  S  G  T++    +R +  AT V
Sbjct: 1596 KATGTPLPVPPVISSQGGTVTVLVNEPARLECEATGV 1632



 Score = 92.7 bits (220), Expect = 6e-17
 Identities = 69/232 (29%), Positives = 100/232 (43%), Gaps = 14/232 (6%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P I   P         P TL CRA G PSP I W K G L+        L + G  F+ +
Sbjct: 781  PTIQHGPQVFNTIEGTPVTLPCRAIGVPSPEITWTKEGKLLYLGGPDFFLDSDGSLFINS 840

Query: 72   THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE------FRLEPESKQSAQGDTV 125
              G   +++G + C ATN+ G A SR   L V V             EP      +G+  
Sbjct: 841  PSG---NESGEFICMATNAAGHA-SRRVQLTVYVRPRSNAEGPGSSAEPLRMSVTEGEDA 896

Query: 126  VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
            +L C      P P + W K  + L+     R H +   ++ I +++ +D+G Y C+A N 
Sbjct: 897  ILPC-EVHSVPPPTITWAK--ERLISPFAPRHHPLPSCSMKILESKVSDSGIYVCVASNI 953

Query: 186  AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
            AG    ++  L + + P +  GP  +  Q G  V   C V G P P + W R
Sbjct: 954  AGNLTLSVL-LSVLVPPSIQPGPRVMKVQVGHPVELPCMVSGVPEPTLTWTR 1004



 Score = 89.4 bits (212), Expect = 5e-16
 Identities = 69/232 (29%), Positives = 102/232 (43%), Gaps = 18/232 (7%)

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLD 260
           P  I+   +V A  GS     C V      ++ W R  GG +  LG +V VLD+ SL+L 
Sbjct: 376 PPAISVKGNVTASPGSRAVLTCHVISTVSFNLTWLR--GGRDARLGPQVNVLDNRSLQLS 433

Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
           +V     G Y C A N  G  S   YLTV + P +++ P +     G+     C+A+G P
Sbjct: 434 SVSPDQSGWYECVAMNEGGVTSEQIYLTVQEEPRVSVHPANQTFSRGDEVHMRCSASGYP 493

Query: 321 EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGS 380
            P + W+   +  +     SR +       DG  +L I +T++ D      C A N AG+
Sbjct: 494 VPRLVWT---HNDMFVKASSRHRMGP----DG--MLAIRNTEQKDG-GVYRCLASNQAGT 543

Query: 381 SFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
                 LT         P++T    +  + +   AV  C A  TP+P I WY
Sbjct: 544 DATNSVLTYIES-----PVVTVALGDVLVALGEAAVLACAASGTPQPEIWWY 590



 Score = 79.0 bits (186), Expect = 7e-13
 Identities = 63/218 (28%), Positives = 97/218 (44%), Gaps = 12/218 (5%)

Query: 18   PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
            P +  V       L C AGG P P++ W K GV V       +L  GG   + +      
Sbjct: 1394 PTERKVVLSASLILECEAGGRPPPSLTWLKDGVPVRHSQSLRVLELGGKIEISSA---TL 1450

Query: 78   SDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
            SD+G Y C AT+  G    + + T+ V    +   +   S        + +EC    G+P
Sbjct: 1451 SDSGRYVCVATSVAGEKEVKYDVTVLVPPFIQGAGVITHSTVII-NHPLEMEC-QATGTP 1508

Query: 137  EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
             P V W K+G+ +   G+       G  L++  A+ +D  R+QC+A N AG  +    T+
Sbjct: 1509 TPVVTWYKDGKPIQ-QGEGWRVAAGGQRLLVSRAQISDTARFQCVAANEAGDIQRDF-TV 1566

Query: 197  KIHIKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLP 231
             +H +P  +    DV+ QT   G S   +C+  G PLP
Sbjct: 1567 VVH-EPPSVPHAGDVINQTILAGFSTQLECKATGTPLP 1603



 Score = 77.4 bits (182), Expect = 2e-12
 Identities = 59/235 (25%), Positives = 98/235 (41%), Gaps = 12/235 (5%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
           ++S E P  I    +VT +    A L C    + S  + W +GG         ++L    
Sbjct: 370 ISSSEPPPAISVKGNVTASPGSRAVLTCHVISTVSFNLTWLRGGRDARLGPQVNVLDNRS 429

Query: 66  LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDT 124
           L     +  +    +G Y C A N  G    +   +++ V  E    + P ++  ++GD 
Sbjct: 430 LQLSSVSPDQ----SGWYECVAMNEGGVTSEQ---IYLTVQEEPRVSVHPANQTFSRGDE 482

Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
           V + C    G P P + W  N   +     SR  +   G L I++  Q D G Y+C+A N
Sbjct: 483 VHMRC-SASGYPVPRLVWTHND--MFVKASSRHRMGPDGMLAIRNTEQKDGGVYRCLASN 539

Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
            AGT ++  + L     P +     DV+   G +    C   G P P++ W ++A
Sbjct: 540 QAGT-DATNSVLTYIESPVVTVALGDVLVALGEAAVLACAASGTPQPEIWWYKAA 593



 Score = 73.7 bits (173), Expect = 3e-11
 Identities = 84/306 (27%), Positives = 118/306 (38%), Gaps = 24/306 (7%)

Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
           G    +A  A+GT +  I   K    P     P D  +  GS+VT  C V G P P V W
Sbjct: 570 GEAAVLACAASGTPQPEIWWYKA--APEFTREPSDTASDIGSNVTLWCLVRGYPDPQVTW 627

Query: 236 RRSAG--GGNMPLGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD- 291
           RR  G    N P     V      L   ++ + DE  Y CEA N  G + A   +TV   
Sbjct: 628 RRQDGLPPFNRPRTYGSVTQSRRGLHFTHLWVEDEAVYVCEAHNHFGKIEAKARITVTGL 687

Query: 292 -PPSINLSPNSVNVESGNVARFTCT-ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
             P I  SP+ ++V         C    G P P   W    N  ++    + D+Y     
Sbjct: 688 VLPVIARSPSVLSVVEDQPVTLPCVLLAGNPLPARQWL--HNYGLV----TTDQY-VKVR 740

Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409
            DG   +   +  + D      C A N  G       L V        P I +GP     
Sbjct: 741 KDGSLHI---ERVRLDHVGDYTCLAENVVGLYNHTTTLNV-----YVIPTIQHGPQVFNT 792

Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468
              +    PC AI  P P I W  EG+ L +      + +DG+L +     ++SG + C+
Sbjct: 793 IEGTPVTLPCRAIGVPSPEITWTKEGKLLYLGGPDFFLDSDGSLFINSPSGNESGEFICM 852

Query: 469 ASSRHG 474
           A++  G
Sbjct: 853 ATNAAG 858



 Score = 56.4 bits (130), Expect = 4e-06
 Identities = 37/140 (26%), Positives = 60/140 (42%), Gaps = 7/140 (5%)

Query: 5   YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
           Y+T  E P +   P + T +R     + C A G P P + W    + V + +   + P  
Sbjct: 459 YLTVQEEPRVSVHPANQTFSRGDEVHMRCSASGYPVPRLVWTHNDMFVKASSRHRMGP-D 517

Query: 65  GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
           G+  +R T      D GVY C A+N  GT  + +   ++        +       A G+ 
Sbjct: 518 GMLAIRNTE---QKDGGVYRCLASNQAGTDATNSVLTYIE--SPVVTVALGDVLVALGEA 572

Query: 125 VVLECLPPRGSPEPNVYWKK 144
            VL C    G+P+P ++W K
Sbjct: 573 AVLAC-AASGTPQPEIWWYK 591



 Score = 50.0 bits (114), Expect = 4e-04
 Identities = 47/198 (23%), Positives = 83/198 (41%), Gaps = 17/198 (8%)

Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
           PP+I++  N V    G+ A  TC         + W   G    + P ++        V D
Sbjct: 376 PPAISVKGN-VTASPGSRAVLTCHVISTVSFNLTWLRGGRDARLGPQVN--------VLD 426

Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
             + L ++    + S     C A+N  G +  +  LTV  +     P ++  P+NQT   
Sbjct: 427 NRS-LQLSSVSPDQS-GWYECVAMNEGGVTSEQIYLTVQEE-----PRVSVHPANQTFSR 479

Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
                  C+A   P P + W      +  + R  +  DG L +++ ++ D G Y C+AS+
Sbjct: 480 GDEVHMRCSASGYPVPRLVWTHNDMFVKASSRHRMGPDGMLAIRNTEQKDGGVYRCLASN 539

Query: 472 RHGKYVWSGAL-LVDSPI 488
           + G    +  L  ++SP+
Sbjct: 540 QAGTDATNSVLTYIESPV 557



 Score = 49.2 bits (112), Expect = 7e-04
 Identities = 55/201 (27%), Positives = 80/201 (39%), Gaps = 36/201 (17%)

Query: 22   TVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAG 81
            TV  + P  + C+A G+P+P + WYK G  +       +  AGG   L  +  ++ SD  
Sbjct: 1491 TVIINHPLEMECQATGTPTPVVTWYKDGKPIQQGEGWRVA-AGGQRLL-VSRAQI-SDTA 1547

Query: 82   VYWCEATNSYGTA-RSRNATLHVA--------VLREE----FRLEPESKQ---------- 118
             + C A N  G   R     +H          V+ +     F  + E K           
Sbjct: 1548 RFQCVAANEAGDIQRDFTVVVHEPPSVPHAGDVINQTILAGFSTQLECKATGTPLPVPPV 1607

Query: 119  -SAQGDTVV--------LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
             S+QG TV         LEC    G P P+  W K+G  +         L +G  L +  
Sbjct: 1608 ISSQGGTVTVLVNEPARLEC-EATGVPSPSFTWLKDGSPVASVPHGLQVLSEGRALSLNS 1666

Query: 170  ARQTDAGRYQCIARNAAGTRE 190
            A  TD G Y C+A NA G ++
Sbjct: 1667 ALVTDTGTYTCVAVNAGGEQQ 1687



 Score = 49.2 bits (112), Expect = 7e-04
 Identities = 31/82 (37%), Positives = 39/82 (47%), Gaps = 4/82 (4%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTH-RSILPAGGLFFLR 70
            P I  Q   VTV  ++PA L C A G PSP+  W K G  V S  H   +L  G    L 
Sbjct: 1606 PVISSQGGTVTVLVNEPARLECEATGVPSPSFTWLKDGSPVASVPHGLQVLSEGRALSLN 1665

Query: 71   ATHGRVHSDAGVYWCEATNSYG 92
            +    + +D G Y C A N+ G
Sbjct: 1666 SA---LVTDTGTYTCVAVNAGG 1684



 Score = 47.2 bits (107), Expect = 0.003
 Identities = 34/106 (32%), Positives = 48/106 (45%), Gaps = 6/106 (5%)

Query: 388  TVTSDDDRPPPI-ITNGPSNQTLPIK---SMAVFPCTAICTPEPIIAWYFEGEALIQNHR 443
            T+T   D PP + +   P N  L  +       FPC A   P+P+I W   G+ L  N  
Sbjct: 999  TLTWTRDVPPVVEVLEPPFNSPLQERVANQRIAFPCPAKGLPKPVIRWLRNGQELTGNEP 1058

Query: 444  R-NVTNDGTLVL-KDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
              ++  DGTL+L   +   DSG Y C A++  G       L V+ P
Sbjct: 1059 GVSILEDGTLLLLASVSPLDSGEYVCAAANDAGSTERKYQLKVNVP 1104



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 31/107 (28%), Positives = 44/107 (41%), Gaps = 5/107 (4%)

Query: 368 NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427
           +++  S++  AG   V G     S  + PP I   G  N T    S AV  C  I T   
Sbjct: 351 SSVSFSSIKPAG---VEGDWEKISSSEPPPAISVKG--NVTASPGSRAVLTCHVISTVSF 405

Query: 428 IIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
            + W   G       + NV ++ +L L  +    SG Y CVA +  G
Sbjct: 406 NLTWLRGGRDARLGPQVNVLDNRSLQLSSVSPDQSGWYECVAMNEGG 452



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 24/93 (25%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 200  IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDG-SL 257
            + P + +    V          +C   G P P   W +      ++P G ++VL +G +L
Sbjct: 1604 VPPVISSQGGTVTVLVNEPARLECEATGVPSPSFTWLKDGSPVASVPHG-LQVLSEGRAL 1662

Query: 258  RLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290
             L++ ++ D G Y+C A N+ G       L VY
Sbjct: 1663 SLNSALVTDTGTYTCVAVNAGGEQQREYDLRVY 1695



 Score = 36.7 bits (81), Expect = 3.9
 Identities = 18/46 (39%), Positives = 25/46 (54%)

Query: 2   SDDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK 47
           ++  +T  E+P +     DV VA  + A L C A G+P P I WYK
Sbjct: 546 TNSVLTYIESPVVTVALGDVLVALGEAAVLACAASGTPQPEIWWYK 591


>UniRef50_A7SM31 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 194

 Score =  151 bits (366), Expect = 1e-34
 Identities = 82/191 (42%), Positives = 111/191 (58%), Gaps = 7/191 (3%)

Query: 106 LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNL 165
           LR +FR EP+      G+  +L+C PP+G P P V W KN +  + DG  R+  V  GNL
Sbjct: 1   LRSKFRAEPKDLSITIGNRAILKCNPPKGRPAPTVTWLKNTKAYVPDG-VRIQKVSPGNL 59

Query: 166 VIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV 225
           VI  A++ D G YQC+A NA G R+S +AT+ I  KP +I  P+DVV   G++  F C+ 
Sbjct: 60  VISIAQKADMGTYQCVAANAVGRRKSRVATVTIKAKPEIIQRPKDVVIVEGNTALFTCKA 119

Query: 226 GGDPLPDVLWRRSAGGGNM-PL---GRVKVLDDGSLRLDNVILADEGEYSCEAEN--SVG 279
            G PLP V W + + G  M P+   GR  V  +G LR+ +V   DEGEY C A +   +G
Sbjct: 120 TGSPLPTVFWEKKSKGQPMFPMQDYGRFFVSSNGELRISSVKKEDEGEYVCSALSPAGLG 179

Query: 280 AVSASGYLTVY 290
           A SA   LTV+
Sbjct: 180 ASSARAMLTVW 190



 Score = 81.8 bits (193), Expect = 1e-13
 Identities = 61/187 (32%), Positives = 89/187 (47%), Gaps = 11/187 (5%)

Query: 208 PEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNVILA 265
           P+D+    G+    +C    G P P V W ++     +P G R++ +  G+L +     A
Sbjct: 9   PKDLSITIGNRAILKCNPPKGRPAPTVTWLKNTKA-YVPDGVRIQKVSPGNLVISIAQKA 67

Query: 266 DEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTM 324
           D G Y C A N+VG   S    +T+   P I   P  V +  GN A FTC ATG P PT+
Sbjct: 68  DMGTYQCVAANAVGRRKSRVATVTIKAKPEIIQRPKDVVIVEGNTALFTCKATGSPLPTV 127

Query: 325 FWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA--GSSF 382
           FW  +     +FP     ++  ++  +G   L I+   K D     VCSA++ A  G+S 
Sbjct: 128 FWEKKSKGQPMFPMQDYGRFFVSS--NG--ELRISSVKKED-EGEYVCSALSPAGLGASS 182

Query: 383 VRGKLTV 389
            R  LTV
Sbjct: 183 ARAMLTV 189



 Score = 71.7 bits (168), Expect = 1e-10
 Identities = 52/180 (28%), Positives = 78/180 (43%), Gaps = 9/180 (5%)

Query: 17  QPLDVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75
           +P D+++     A L C    G P+P + W K     V D  R    + G   +      
Sbjct: 8   EPKDLSITIGNRAILKCNPPKGRPAPTVTWLKNTKAYVPDGVRIQKVSPGNLVISIAQ-- 65

Query: 76  VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGS 135
             +D G Y C A N+ G  +SR AT+ +   + E    P+     +G+T +  C    GS
Sbjct: 66  -KADMGTYQCVAANAVGRRKSRVATVTIKA-KPEIIQRPKDVVIVEGNTALFTC-KATGS 122

Query: 136 PEPNVYWKK--NGQTLLFDGD-SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
           P P V+W+K   GQ +    D  R  +   G L I   ++ D G Y C A + AG   S+
Sbjct: 123 PLPTVFWEKKSKGQPMFPMQDYGRFFVSSNGELRISSVKKEDEGEYVCSALSPAGLGASS 182



 Score = 51.2 bits (117), Expect = 2e-04
 Identities = 51/182 (28%), Positives = 81/182 (44%), Gaps = 19/182 (10%)

Query: 299 PNSVNVESGNVARFTCTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
           P  +++  GN A   C    GRP PT+ W ++  +  +  G+   K     V  G  V++
Sbjct: 9   PKDLSITIGNRAILKCNPPKGRPAPTVTW-LKNTKAYVPDGVRIQK-----VSPGNLVIS 62

Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
           I    K D   T  C A N  G    R K  V +   +  P I   P +  +   + A+F
Sbjct: 63  I--AQKADM-GTYQCVAANAVG----RRKSRVATVTIKAKPEIIQRPKDVVIVEGNTALF 115

Query: 418 PCTAICTPEPIIAWY--FEGEAL--IQNHRRN-VTNDGTLVLKDLDKSDSGTYTCVASSR 472
            C A  +P P + W    +G+ +  +Q++ R  V+++G L +  + K D G Y C A S 
Sbjct: 116 TCKATGSPLPTVFWEKKSKGQPMFPMQDYGRFFVSSNGELRISSVKKEDEGEYVCSALSP 175

Query: 473 HG 474
            G
Sbjct: 176 AG 177



 Score = 40.3 bits (90), Expect = 0.31
 Identities = 31/103 (30%), Positives = 43/103 (41%), Gaps = 8/103 (7%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG----VLVVSDTHRSIL 61
           VT    P II++P DV +     A   C+A GSP P + W K      +  + D  R  +
Sbjct: 90  VTIKAKPEIIQRPKDVVIVEGNTALFTCKATGSPLPTVFWEKKSKGQPMFPMQDYGRFFV 149

Query: 62  PAGGLFFLRATHGRVHSDAGVYWCEATNSYGT-ARSRNATLHV 103
            + G   + +       D G Y C A +  G  A S  A L V
Sbjct: 150 SSNGELRISSVK---KEDEGEYVCSALSPAGLGASSARAMLTV 189



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 35/129 (27%), Positives = 56/129 (43%), Gaps = 6/129 (4%)

Query: 404 PSNQTLPIKSMAVFPCTAIC-TPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKDLDKSD 461
           P + ++ I + A+  C      P P + W    +A + +  R    + G LV+    K+D
Sbjct: 9   PKDLSITIGNRAILKCNPPKGRPAPTVTWLKNTKAYVPDGVRIQKVSPGNLVISIAQKAD 68

Query: 462 SGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSV- 520
            GTY CVA++  G+   S    V     P I   R  DV  + G  T   T   T + + 
Sbjct: 69  MGTYQCVAANAVGRRK-SRVATVTIKAKPEI-IQRPKDVVIVEG-NTALFTCKATGSPLP 125

Query: 521 TLSWSQNNK 529
           T+ W + +K
Sbjct: 126 TVFWEKKSK 134


>UniRef50_UPI000155CDCD Cluster: PREDICTED: similar to adlican; n=1;
            Ornithorhynchus anatinus|Rep: PREDICTED: similar to
            adlican - Ornithorhynchus anatinus
          Length = 2908

 Score =  151 bits (365), Expect = 1e-34
 Identities = 144/500 (28%), Positives = 214/500 (42%), Gaps = 50/500 (10%)

Query: 9    GEAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYK--GGVLVVSDT--HRSILPA 63
            GE P I+ +    +++     A L C A G P P + W +   G L+  +T  HR  +  
Sbjct: 1941 GEKPRIVTKSAPTLSIPAETDAVLPCEATGEPRPFVTWTRIATGALMTPNTKTHRFEVLR 2000

Query: 64   GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-G 122
             G F +R    +   D G Y C ATN +G  +   A L VA    E         +   G
Sbjct: 2001 NGTFVIRNAQPQ---DGGRYLCTATNLHGLDKMAVA-LSVAARPPEMATAHYRDVTVYLG 2056

Query: 123  DTVVLECLPPRGSPEPNVYW----KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY 178
            DT+ +ECL   G P P++ W    +K  QT+    ++R+ L     L I+DA  +D G Y
Sbjct: 2057 DTIAMECLAD-GVPPPHISWIFPDRKVWQTVS-TAEARITLHRNRTLSIKDATFSDRGVY 2114

Query: 179  QCIARNAAGTRESAIATLKIHIKPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
            +C+A NAAGT +S    L +   P +I     E++    G  V   C     P P + WR
Sbjct: 2115 KCVAGNAAGT-DSLAVRLHVAALPPIIQQEKRENISLPPGIGVNIHCSAKAAPPPTIRWR 2173

Query: 237  RSAGGGNMPL----GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV--- 289
               G    P     G V V  +G+L L +V   D G Y C A N+VG    +  LTV   
Sbjct: 2174 LLDGTQIRPSQFANGNVFVFPNGTLYLRHVAPEDSGTYECVAANAVGVARRTVRLTVRQG 2233

Query: 290  -YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI--IFPGMSRDKYHA 346
              +      SP   +V  G   R  C+A+G P PT+ W +   R I  +F   +R +  A
Sbjct: 2234 GAEARIARTSPRQTDVTYGGTLRLDCSASGDPRPTILWRLPSKRMIDSLFSLETRTRVLA 2293

Query: 347  TAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN 406
                  + V ++ D D  D     +C A N  G      ++ VT    RP  I      +
Sbjct: 2294 NG---SLVVQSVTDGDAGD----YLCVARNRLGDDSAALRVNVTM---RPARIERREEPD 2343

Query: 407  QTLPIKSMAVFPCTAICTPEPIIAWYF-EG---EALIQN-------HRRNVTNDGTLVLK 455
            + +         C A   P P ++W   +G    AL+Q+        R  + ++GTL   
Sbjct: 2344 RRVAYGGALTVDCVASGLPVPDVSWSLPDGSTVNALMQSDDGGGGAKRYVLFHNGTLYFH 2403

Query: 456  DLDKSDSGTYTCVASSRHGK 475
            D+   + G YTC+A +  G+
Sbjct: 2404 DVGLGEQGDYTCLAENPMGR 2423



 Score =  135 bits (327), Expect = 6e-30
 Identities = 140/481 (29%), Positives = 207/481 (43%), Gaps = 57/481 (11%)

Query: 31   LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF-FLRATHGRVH---SDAGVYWCE 86
            ++C A  +P P IRW    +L  +    S    G +F F   T    H    D+G Y C 
Sbjct: 2158 IHCSAKAAPPPTIRWR---LLDGTQIRPSQFANGNVFVFPNGTLYLRHVAPEDSGTYECV 2214

Query: 87   ATNSYGTARSRNATLHVAVLREEFRL---EPESKQSAQGDTVVLECLPPRGSPEPNVYWK 143
            A N+ G AR R   L V     E R+    P       G T+ L+C    G P P + W+
Sbjct: 2215 AANAVGVAR-RTVRLTVRQGGAEARIARTSPRQTDVTYGGTLRLDC-SASGDPRPTILWR 2272

Query: 144  KNGQTL---LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
               + +   LF  ++R  ++  G+LV+Q     DAG Y C+ARN  G  +SA   + + +
Sbjct: 2273 LPSKRMIDSLFSLETRTRVLANGSLVVQSVTDGDAGDYLCVARNRLGD-DSAALRVNVTM 2331

Query: 201  KPYLITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG----------GNMPLGR 248
            +P  I   E  D     G ++T  C   G P+PDV W    G           G     R
Sbjct: 2332 RPARIERREEPDRRVAYGGALTVDCVASGLPVPDVSWSLPDGSTVNALMQSDDGGGGAKR 2391

Query: 249  VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-DPPSINLSPNSV-NVES 306
              +  +G+L   +V L ++G+Y+C AEN +G       + V  +P +I    +SV +V  
Sbjct: 2392 YVLFHNGTLYFHDVGLGEQGDYTCLAENPMGRDEMRIRVRVLAEPAAIRNKGDSVADVLY 2451

Query: 307  GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
            G      C + G P PT+ W    N  I  P  S  KY  +   DG   L I +  ++D 
Sbjct: 2452 GEAVSVACESRGEPAPTVTWLSPANLPI--PPASA-KYRVSR--DG--TLLIREARRSDG 2504

Query: 367  RNTIVCSAVNYAGS--SFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA------VFP 418
             N   C   N AG     VR +++V     R P I  NG  +    ++ +A      +  
Sbjct: 2505 GN-YTCVVRNGAGEDRKVVRVRVSV-----RRPRI--NGSPDAVTTVREIAARGDRKLID 2556

Query: 419  CTAICTPEPIIAWYF-EGEAL---IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
            C A   P P + W F +G  L       R  V  +GTL ++DL +SDS    C+  +  G
Sbjct: 2557 CRAEGVPAPRVLWAFPQGVVLPAPYYGRRITVHRNGTLDVRDLRESDSVRLVCIGRNEGG 2616

Query: 475  K 475
            +
Sbjct: 2617 E 2617



 Score =  116 bits (278), Expect = 5e-24
 Identities = 140/537 (26%), Positives = 214/537 (39%), Gaps = 56/537 (10%)

Query: 16   EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG----LFFLRA 71
            E+P D  VA     T++C A G P P + W       V+   +S    GG    + F   
Sbjct: 2340 EEP-DRRVAYGGALTVDCVASGLPVPDVSWSLPDGSTVNALMQSDDGGGGAKRYVLFHNG 2398

Query: 72   T---HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GDTV 125
            T   H     + G Y C A N  G    R   + V VL E   +  +    A    G+ V
Sbjct: 2399 TLYFHDVGLGEQGDYTCLAENPMGRDEMR---IRVRVLAEPAAIRNKGDSVADVLYGEAV 2455

Query: 126  VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
             + C   RG P P V W       +    ++  +   G L+I++AR++D G Y C+ RN 
Sbjct: 2456 SVAC-ESRGEPAPTVTWLSPANLPIPPASAKYRVSRDGTLLIREARRSDGGNYTCVVRNG 2514

Query: 186  AGTRESAIATLKIHIKPYLITGPEDVV------AQTGSSVTFQCRVGGDPLPDVLWRRSA 239
            AG  +  +  +++ ++   I G  D V      A  G      CR  G P P VLW    
Sbjct: 2515 AG-EDRKVVRVRVSVRRPRINGSPDAVTTVREIAARGDRKLIDCRAEGVPAPRVLW-AFP 2572

Query: 240  GGGNMPL----GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295
             G  +P      R+ V  +G+L + ++  +D     C   N  G       LTV DP   
Sbjct: 2573 QGVVLPAPYYGRRITVHRNGTLDVRDLRESDSVRLVCIGRNEGGEARLVVQLTVLDPRGG 2632

Query: 296  NLSPNSVNVE----SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
             +  + V+ E    +G+     C+A GRP+PT+ W +     +  PG  R          
Sbjct: 2633 PVFRDPVDEEITAAAGHTINLNCSAEGRPDPTVLWILPDGSEV--PGGRR---LGRFFHK 2687

Query: 352  GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
            G  VL I+     D+     C A N AGS+  R  L V     RP  +    P  +TL  
Sbjct: 2688 GDGVLHISALAPADA-GPYRCLARNPAGSAQRRVSLGVGPGPARPVSV----PGGETL-- 2740

Query: 412  KSMAVFPCTAICTPEPIIAWYFEGEALIQN----HRRNVTNDGTLVLKDLDKSDSGTYTC 467
                +  C    +    ++W   G  ++       R  +  +G+L +++    D GTY C
Sbjct: 2741 ----LLHCGPPGSRPVGVSWTLPGGRVLDRPQTAGRFTLFENGSLSVREASGEDRGTYLC 2796

Query: 468  -VASSRHGKYVWSGALLVDSPINPNIHFFRAADV----SSLPGPPTKPITHNVTDTS 519
              A+  HG  + S  + V +P  P +   RA        ++ G P   +T  + D S
Sbjct: 2797 RAAAVDHGPPLTSVPVAVVAPTAPRVVRSRAGSSVRLDCAVAGVPGAEVTWRLPDGS 2853



 Score = 85.4 bits (202), Expect = 8e-15
 Identities = 91/295 (30%), Positives = 129/295 (43%), Gaps = 40/295 (13%)

Query: 14   IIEQPLD--VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG---GLFF 68
            +   P+D  +T A      LNC A G P P + W      ++ D   S +P G   G FF
Sbjct: 2634 VFRDPVDEEITAAAGHTINLNCSAEGRPDPTVLW------ILPDG--SEVPGGRRLGRFF 2685

Query: 69   LRATHGRVH------SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122
             +   G +H      +DAG Y C A N  G+A+ R  +L V          P S     G
Sbjct: 2686 HKGD-GVLHISALAPADAGPYRCLARNPAGSAQ-RRVSLGVG----PGPARPVSVPG--G 2737

Query: 123  DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS--RMHLVDGGNLVIQDARQTDAGRYQC 180
            +T++L C PP GS    V W   G  +L    +  R  L + G+L +++A   D G Y C
Sbjct: 2738 ETLLLHCGPP-GSRPVGVSWTLPGGRVLDRPQTAGRFTLFENGSLSVREASGEDRGTYLC 2796

Query: 181  IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
              R AA      + ++ + +     T P  V ++ GSSV   C V G P  +V WR   G
Sbjct: 2797 --RAAAVDHGPPLTSVPVAV--VAPTAPRVVRSRAGSSVRLDCAVAGVPGAEVTWRLPDG 2852

Query: 241  -----GGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
                 G    L   K+L   G+L +      D G YSC A N +G+ S + Y+ V
Sbjct: 2853 SPLTAGPRARLYGNKLLHPQGALLIQRATPGDAGFYSCTARNQLGSHSQTTYVHV 2907



 Score = 46.0 bits (104), Expect = 0.006
 Identities = 46/168 (27%), Positives = 70/168 (41%), Gaps = 13/168 (7%)

Query: 122 GDTVVLECLPPRGSPEPNVYWK-KNGQTLLF--DG-DSRMHLVDGGNLVIQDARQTDAGR 177
           G    L C   R S  P + W   +G  L    DG D R  + + G L ++ A   D+G 
Sbjct: 518 GSGFELRC-DARASESPEILWVLPDGSALRAPSDGRDGRFSVREDGRLTLRAAGYPDSGP 576

Query: 178 YQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVA---QTGSSVTFQCRVGGDPLPDVL 234
           Y+C+AR    T +S +  + +   P +  G  +V A   + G  +T  C     P   + 
Sbjct: 577 YRCVARVRDET-DSVVHRVSVQ-PPEVRPGDGEVSAIEKRAGEPITLPCGALAIPEAQLS 634

Query: 235 W---RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279
           W    R          R  +L++G+L +    +AD G Y C A N  G
Sbjct: 635 WILPSREVVSDFSNSSRGFLLENGTLLIPGGQVADTGYYRCVAVNRQG 682



 Score = 40.7 bits (91), Expect = 0.24
 Identities = 49/168 (29%), Positives = 70/168 (41%), Gaps = 19/168 (11%)

Query: 31  LNCRAGGSPSPAIRWY--KGGVL-VVSDTH--RSILPAGGLFFLRATHGRVHSDAGVYWC 85
           L C A  S SP I W    G  L   SD    R  +   G   LRA     + D+G Y C
Sbjct: 523 LRCDARASESPEILWVLPDGSALRAPSDGRDGRFSVREDGRLTLRAAG---YPDSGPYRC 579

Query: 86  EATNSYGTARSRNATLH-VAVLREEFRL---EPESKQSAQGDTVVLECLPPRGSPEPNVY 141
            A     T    ++ +H V+V   E R    E  + +   G+ + L C      PE  + 
Sbjct: 580 VARVRDET----DSVVHRVSVQPPEVRPGDGEVSAIEKRAGEPITLPC-GALAIPEAQLS 634

Query: 142 WKKNGQTLL--FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
           W    + ++  F   SR  L++ G L+I   +  D G Y+C+A N  G
Sbjct: 635 WILPSREVVSDFSNSSRGFLLENGTLLIPGGQVADTGYYRCVAVNRQG 682



 Score = 36.7 bits (81), Expect = 3.9
 Identities = 17/61 (27%), Positives = 31/61 (50%), Gaps = 4/61 (6%)

Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRN----VTNDGTLVLKDLDKSDSGTYTCVASSRH 473
           PC A+  PE  ++W      ++ +   +    +  +GTL++     +D+G Y CVA +R 
Sbjct: 622 PCGALAIPEAQLSWILPSREVVSDFSNSSRGFLLENGTLLIPGGQVADTGYYRCVAVNRQ 681

Query: 474 G 474
           G
Sbjct: 682 G 682



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 34/138 (24%), Positives = 48/138 (34%), Gaps = 11/138 (7%)

Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG-NMPL----GRVKVLDDGSLRL 259
           + G   V+A  GS    +C       P++LW    G     P     GR  V +DG L L
Sbjct: 509 VDGARTVLA--GSGFELRCDARASESPEILWVLPDGSALRAPSDGRDGRFSVREDGRLTL 566

Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV---ESGNVARFTCTA 316
                 D G Y C A       S    ++V  PP +      V+     +G      C A
Sbjct: 567 RAAGYPDSGPYRCVARVRDETDSVVHRVSV-QPPEVRPGDGEVSAIEKRAGEPITLPCGA 625

Query: 317 TGRPEPTMFWSVEGNRTI 334
              PE  + W +     +
Sbjct: 626 LAIPEAQLSWILPSREVV 643


>UniRef50_Q0E8G9 Cluster: CG33274-PB; n=9; Endopterygota|Rep:
            CG33274-PB - Drosophila melanogaster (Fruit fly)
          Length = 1876

 Score =  149 bits (362), Expect = 3e-34
 Identities = 175/779 (22%), Positives = 311/779 (39%), Gaps = 57/779 (7%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            PYI E P  +T        + C   G P   I W + G  +  +  +     G L   + 
Sbjct: 382  PYIREMP-KITGISGSDLIVKCPVAGYPIDKIHWERDGQTLPINRRQRAYNNGTLIIEQL 440

Query: 72   THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
                   DAG Y C A N       RN  + V V  +   ++  +    +G    + C  
Sbjct: 441  QR---LEDAGTYTCMAQNKQKQTSRRNVEIQVLVPPKIMPIQAMTNMLREGMRAAISCQI 497

Query: 132  PRGSPEPNVYWKKNGQTLLFDGDSRMHLVD--GGNLVIQDARQTDAGRYQCIARNAAGTR 189
              G    +  W++NG+ L+  G+     +D    +LVI+      +G Y CIA N AGT 
Sbjct: 498  LEGDLPVSFRWERNGKPLIGTGNEVFRRLDEYSASLVIEHISSDHSGNYTCIASNVAGTE 557

Query: 190  ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GN---- 243
               +  L +++ P  I  P+D  AQ G+ V   C+  G P P + W+++ G   G     
Sbjct: 558  RFTVP-LTVNVPPKWILEPKDSSAQAGADVLLHCQSSGYPTPTITWKKAIGPTPGEYKDF 616

Query: 244  MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSV 302
            +    V++  +G++    +    +G + CEA+N++G+ VS   +L V  P         +
Sbjct: 617  LYEPTVQLFPNGTIFFKKISKESQGHFLCEAKNNIGSGVSKVIFLKVNVPAHFQTKTKQI 676

Query: 303  NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGM-SRDKYHATAVFDG-VTVLTIND 360
            +V  G      C   G       W ++  +  +   + SR       + DG V+ L I+ 
Sbjct: 677  SVAKGKQVHVQCNVQGDNPIDFKWKIQATQQYLDESLDSRYTIRDQVLDDGMVSELGISH 736

Query: 361  TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
            T + D+    +C A N  G   +  +L V    ++P  +  N   +++L +     F   
Sbjct: 737  TYRQDT-GIYICQASNAFGQDEMSIQLIVQEVPEQPKNLRINSQQSRSLQLTWSQPF--- 792

Query: 421  AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
            A  +P      Y++  + I  +  ++T  G   + ++ +        +  S   K    G
Sbjct: 793  AGNSPIEEYHIYYKQISDIWQNAEHLTIAGAQTVINIQQLRPAKAYHIRMSAENKL---G 849

Query: 481  ALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSIL-GYQ 539
            A    S  +  +      +V S  GPP        + T + ++W    +   + IL GY 
Sbjct: 850  A----SEFSEVVQVTTLEEVPS--GPPLAVRAEPKSSTEIFVTWDAPERDHWNGILLGYY 903

Query: 540  VEVFSRETLSGNNT-PRNSRGWVVIARRVHQTHYVVKSLIPGIT-YMFIVRTENSHGLSG 597
            V      T       P     +  +  R H     V + +   T Y  IV+   S G SG
Sbjct: 904  VGYQMSLTPEDKEVNPTQGFSFKTVEVRSHFGGETVLANLNKFTQYHVIVQAYTSQG-SG 962

Query: 598  PSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATP-IDSKTIKLMWEIL 656
            P     +V   +D  S       S     + ++L    + +  + P ID +  K+     
Sbjct: 963  PPSKEIAVQTMEDVPS-------SPPESPQCDVLGSTSIYITWSPPDIDGQNGKI----- 1010

Query: 657  NFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEG 716
                 +G  +++  +D +  E + + +  +N     E  +LRKYT Y  +++ + K  +G
Sbjct: 1011 -----KGYKVFYISVDEL-YETDPEVVKSTNQYVTIE--NLRKYTNYTVWVLAYTKVGDG 1062

Query: 717  KPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLD 775
              +     +T +DVP  P   I+    +++ + + W PP+  L NG ITGY   ++ L+
Sbjct: 1063 MKTKPFYCRTHEDVPSAPQA-IKAIPASSSKIIISWLPPD--LPNGDITGYTFYMSMLE 1118



 Score =  118 bits (285), Expect = 7e-25
 Identities = 124/475 (26%), Positives = 194/475 (40%), Gaps = 39/475 (8%)

Query: 30  TLNCRAGGSPSPAIRWYK---GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
           TL C A G P P  RW+K     +L +  + R  + + GL  L+ T  R+  D+G Y C 
Sbjct: 116 TLPCIAQGHPVPTYRWFKEENEQLLPLQLSERITIVSAGL--LKITKARL-EDSGKYLCW 172

Query: 87  ATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146
             N+ G    + +    A L     L+P+ +          +C+   G P  +V W  +G
Sbjct: 173 VNNTAGEETIQVSLTVTAPLTA--HLQPQVQTVDVDKDAQFQCI-VSGHPVHDVNWLHDG 229

Query: 147 QTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT 206
           + +L D    + L D   L+I+  ++ D G YQC   N     +S          P L+ 
Sbjct: 230 KPILRDNRVEI-LTDPPRLIIKKVQKEDPGMYQCFVSNEWEQIQSTAELQLGDASPELLY 288

Query: 207 GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP------LGR-VKVLDD--GSL 257
              +   Q G +V+ +C   G+PLP   W  S  G  +P      +G+ V + DD    +
Sbjct: 289 WFSEQTLQPGPTVSLKCVATGNPLPQFTW--SLDGFPIPDSSRFLVGQYVTIHDDVISHV 346

Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
            + NV   D GEY+C A+N++G VS S  + +Y  P I   P    + SG+     C   
Sbjct: 347 NISNVKEEDGGEYTCTAQNAIGKVSHSAKVNIYGLPYIREMPKITGI-SGSDLIVKCPVA 405

Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
           G P   + W  +G +T+      R   + T        L I    + +   T  C A N 
Sbjct: 406 GYPIDKIHWERDG-QTLPINRRQRAYNNGT--------LIIEQLQRLEDAGTYTCMAQNK 456

Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGE 436
              +    +  V      PP I+        L     A   C  +    P+   W   G+
Sbjct: 457 QKQT---SRRNVEIQVLVPPKIMPIQAMTNMLREGMRAAISCQILEGDLPVSFRWERNGK 513

Query: 437 ALI----QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
            LI    +  RR      +LV++ +    SG YTC+AS+  G   ++  L V+ P
Sbjct: 514 PLIGTGNEVFRRLDEYSASLVIEHISSDHSGNYTCIASNVAGTERFTVPLTVNVP 568



 Score =  117 bits (281), Expect = 2e-24
 Identities = 129/488 (26%), Positives = 204/488 (41%), Gaps = 38/488 (7%)

Query: 127 LECLPPRGSPEPNVYWKK--NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
           L C+  +G P P   W K  N Q L      R+ +V  G L I  AR  D+G+Y C   N
Sbjct: 117 LPCIA-QGHPVPTYRWFKEENEQLLPLQLSERITIVSAGLLKITKARLEDSGKYLCWVNN 175

Query: 185 AAGTRESAI-----ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
            AG     +     A L  H++P + T   D  AQ      FQC V G P+ DV W    
Sbjct: 176 TAGEETIQVSLTVTAPLTAHLQPQVQTVDVDKDAQ------FQCIVSGHPVHDVNWLHD- 228

Query: 240 GGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP-PSINL 297
           G   +   RV++L D   L +  V   D G Y C   N    + ++  L + D  P +  
Sbjct: 229 GKPILRDNRVEILTDPPRLIIKKVQKEDPGMYQCFVSNEWEQIQSTAELQLGDASPELLY 288

Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY--HATAVFDGVTV 355
             +   ++ G      C ATG P P   WS++G      P  SR     + T   D ++ 
Sbjct: 289 WFSEQTLQPGPTVSLKCVATGNPLPQFTWSLDG---FPIPDSSRFLVGQYVTIHDDVISH 345

Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTS-DDDRPPPIITNGPSNQTLPIKSM 414
           + I++  + D      C+A N  G      K+ +      R  P IT G S   L +K  
Sbjct: 346 VNISNVKEEDG-GEYTCTAQNAIGKVSHSAKVNIYGLPYIREMPKIT-GISGSDLIVK-- 401

Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDK-SDSGTYTCVASSRH 473
               C     P   I W  +G+ L  N R+   N+GTL+++ L +  D+GTYTC+A ++ 
Sbjct: 402 ----CPVAGYPIDKIHWERDGQTLPINRRQRAYNNGTLIIEQLQRLEDAGTYTCMAQNKQ 457

Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVT--DTSVTLSWSQNNK-- 529
            K      + +   + P I   +A   + L       I+  +   D  V+  W +N K  
Sbjct: 458 -KQTSRRNVEIQVLVPPKIMPIQAM-TNMLREGMRAAISCQILEGDLPVSFRWERNGKPL 515

Query: 530 IGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRT 589
           IG+ + +  +++ +S   +  + +  +S  +  IA  V  T      L   +   +I+  
Sbjct: 516 IGTGNEVFRRLDEYSASLVIEHISSDHSGNYTCIASNVAGTERFTVPLTVNVPPKWILEP 575

Query: 590 ENSHGLSG 597
           ++S   +G
Sbjct: 576 KDSSAQAG 583



 Score = 97.5 bits (232), Expect = 2e-18
 Identities = 116/480 (24%), Positives = 187/480 (38%), Gaps = 40/480 (8%)

Query: 17  QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV 76
           QP   TV   + A   C   G P   + W   G  ++ D    IL       ++      
Sbjct: 197 QPQVQTVDVDKDAQFQCIVSGHPVHDVNWLHDGKPILRDNRVEILTDPPRLIIKKVQ--- 253

Query: 77  HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDTVVLECLPPRGS 135
             D G+Y C  +N +   +S  A L +     E  L   S+Q+ Q G TV L+C+   G+
Sbjct: 254 KEDPGMYQCFVSNEWEQIQS-TAELQLGDASPEL-LYWFSEQTLQPGPTVSLKCV-ATGN 310

Query: 136 PEPNVYWKKNG------QTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
           P P   W  +G         L      +H     ++ I + ++ D G Y C A+NA G +
Sbjct: 311 PLPQFTWSLDGFPIPDSSRFLVGQYVTIHDDVISHVNISNVKEEDGGEYTCTAQNAIG-K 369

Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-R 248
            S  A + I+  PY+   P+ +   +GS +  +C V G P+  + W R   G  +P+  R
Sbjct: 370 VSHSAKVNIYGLPYIREMPK-ITGISGSDLIVKCPVAGYPIDKIHWERD--GQTLPINRR 426

Query: 249 VKVLDDGSLRLDNV-ILADEGEYSCEAENSVGAVSASGY-LTVYDPPSINLSPNSVN-VE 305
            +  ++G+L ++ +  L D G Y+C A+N     S     + V  PP I       N + 
Sbjct: 427 QRAYNNGTLIIEQLQRLEDAGTYTCMAQNKQKQTSRRNVEIQVLVPPKIMPIQAMTNMLR 486

Query: 306 SGNVARFTCTATGRPEPTMF-WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
            G  A  +C       P  F W   G   I   G   + +      D  +   + +   +
Sbjct: 487 EGMRAAISCQILEGDLPVSFRWERNGKPLI---GTGNEVFRR---LDEYSASLVIEHISS 540

Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
           D      C A N AG+     + TV    + PP  I   P + +    +  +  C +   
Sbjct: 541 DHSGNYTCIASNVAGTE----RFTVPLTVNVPPKWILE-PKDSSAQAGADVLLHCQSSGY 595

Query: 425 PEPIIAWY-------FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
           P P I W         E +  +      +  +GT+  K + K   G + C A +  G  V
Sbjct: 596 PTPTITWKKAIGPTPGEYKDFLYEPTVQLFPNGTIFFKKISKESQGHFLCEAKNNIGSGV 655



 Score = 76.6 bits (180), Expect = 4e-12
 Identities = 49/178 (27%), Positives = 83/178 (46%), Gaps = 7/178 (3%)

Query: 653  WEILNFYYLEGLFIYFRPLD---NITIEYEMKTILHSNDVSGFEI-TSLRKYTKYEFFLI 708
            W  +   Y  G  +   P D   N T  +  KT+   +   G  +  +L K+T+Y   + 
Sbjct: 895  WNGILLGYYVGYQMSLTPEDKEVNPTQGFSFKTVEVRSHFGGETVLANLNKFTQYHVIVQ 954

Query: 709  PFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYN 768
             +  +  G PS     QT++DVP  PP + +  +L +T++++ WSPP++  QNG I GY 
Sbjct: 955  AYTSQGSGPPSKEIAVQTMEDVPSSPPESPQCDVLGSTSIYITWSPPDIDGQNGKIKGYK 1014

Query: 769  VVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVY 826
            V    +D         + +T    T   + NL    +Y+V + A T +G G  ++  Y
Sbjct: 1015 VFYISVDELYETDPEVVKSTNQYVT---IENLRKYTNYTVWVLAYTKVGDGMKTKPFY 1069



 Score = 64.1 bits (149), Expect = 2e-08
 Identities = 89/384 (23%), Positives = 142/384 (36%), Gaps = 47/384 (12%)

Query: 122 GDTVVLECLPPRGSPE---PNVYWKKNGQTLLFDGD--SRMHLVDGGNLVIQDARQTDAG 176
           G+T VL+C  P    E      + +  G  L  + D   +  ++  G L I +A   DA 
Sbjct: 3   GNTAVLKCQVPSYMSEFVLVTAWVQDTGMHLYPNTDIGGKYTVLSNGELYINNAGPNDAY 62

Query: 177 R-YQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT-------------GSSVTFQ 222
           + Y C   N   T E  I+T    I   ++T P+ +V                    T  
Sbjct: 63  KSYTCRTVNRL-TGEVQISTYPGRI---IVTEPKGMVQPRINVEKHSMRHVVLNGQTTLP 118

Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLG---RVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279
           C   G P+P   W +      +PL    R+ ++  G L++    L D G+Y C   N+ G
Sbjct: 119 CIAQGHPVPTYRWFKEENEQLLPLQLSERITIVSAGLLKITKARLEDSGKYLCWVNNTAG 178

Query: 280 AVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGM 339
             +    LTV  P + +L P    V+    A+F C  +G P   + W  +G   +     
Sbjct: 179 EETIQVSLTVTAPLTAHLQPQVQTVDVDKDAQFQCIVSGHPVHDVNWLHDGKPIL----- 233

Query: 340 SRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPI 399
            RD  +   +      L I    K D      C    +  + + + + T         P 
Sbjct: 234 -RD--NRVEILTDPPRLIIKKVQKEDP-GMYQC----FVSNEWEQIQSTAELQLGDASPE 285

Query: 400 ITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR----RNVTNDGTLV-- 453
           +    S QTL         C A   P P   W  +G  +  + R    + VT    ++  
Sbjct: 286 LLYWFSEQTLQPGPTVSLKCVATGNPLPQFTWSLDGFPIPDSSRFLVGQYVTIHDDVISH 345

Query: 454 --LKDLDKSDSGTYTCVASSRHGK 475
             + ++ + D G YTC A +  GK
Sbjct: 346 VNISNVKEEDGGEYTCTAQNAIGK 369



 Score = 61.3 bits (142), Expect = 2e-07
 Identities = 52/217 (23%), Positives = 86/217 (39%), Gaps = 29/217 (13%)

Query: 393  DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTL 452
            +++ P  I +       P K     PC  +  P P+  W  +G  +  + R+ +  +GTL
Sbjct: 1172 NNKVPARIVSFSQRIVTPWKEHLELPCRKVGAPAPVTIWRQDGHNMETSARKTIAKNGTL 1231

Query: 453  VLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPIT 512
             +K+   SD+G YTC   +  GK      ++V  P                P  P   + 
Sbjct: 1232 YMKECQASDAGNYTCSVENTWGKDEIVYNIVVKVP----------------PEAPNLTVI 1275

Query: 513  HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHY 572
            +  TD S+ L W  N+  G S ILGY +           N  R++  W  +      T +
Sbjct: 1276 NAYTD-SLLLEWMDNSH-GGSPILGYVI-----------NYKRDNGDWEELQVDSKTTSH 1322

Query: 573  VVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
            ++ +L  G  Y   +   N  G   P  + +S T G+
Sbjct: 1323 LLTNLWCGTRYQLYITAYNKIGTGLPCDIVNSYTKGN 1359



 Score = 57.6 bits (133), Expect = 2e-06
 Identities = 48/190 (25%), Positives = 77/190 (40%), Gaps = 12/190 (6%)

Query: 646 SKTIKLMWE--ILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKY 703
           S++++L W         +E   IY++ + +I    E  TI  +  V    I  LR    Y
Sbjct: 781 SRSLQLTWSQPFAGNSPIEEYHIYYKQISDIWQNAEHLTIAGAQTV--INIQQLRPAKAY 838

Query: 704 EFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGI 763
              +    K    + S      TL++VP GPP+ +     ++T + + W  PE    NGI
Sbjct: 839 HIRMSAENKLGASEFSEVVQVTTLEEVPSGPPLAVRAEPKSSTEIFVTWDAPERDHWNGI 898

Query: 764 ITGYNVVVNWLDVPANK--------SMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETI 815
           + GY V       P +K        S   +    H     ++ NL     Y V + A T 
Sbjct: 899 LLGYYVGYQMSLTPEDKEVNPTQGFSFKTVEVRSHFGGETVLANLNKFTQYHVIVQAYTS 958

Query: 816 IGLGPFSQKV 825
            G GP S+++
Sbjct: 959 QGSGPPSKEI 968



 Score = 46.0 bits (104), Expect = 0.006
 Identities = 54/204 (26%), Positives = 83/204 (40%), Gaps = 22/204 (10%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG-GVL------VVSDTHR 58
           +T    P  I +P D +        L+C++ G P+P I W K  G         + +   
Sbjct: 563 LTVNVPPKWILEPKDSSAQAGADVLLHCQSSGYPTPTITWKKAIGPTPGEYKDFLYEPTV 622

Query: 59  SILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ 118
            + P G +FF + +        G + CEA N+ G+  S+   L V V    F+ + +   
Sbjct: 623 QLFPNGTIFFKKIS----KESQGHFLCEAKNNIGSGVSKVIFLKVNV-PAHFQTKTKQIS 677

Query: 119 SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDG--DSRM----HLVDGG---NLVIQD 169
            A+G  V ++C   +G    +  WK        D   DSR      ++D G    L I  
Sbjct: 678 VAKGKQVHVQC-NVQGDNPIDFKWKIQATQQYLDESLDSRYTIRDQVLDDGMVSELGISH 736

Query: 170 ARQTDAGRYQCIARNAAGTRESAI 193
             + D G Y C A NA G  E +I
Sbjct: 737 TYRQDTGIYICQASNAFGQDEMSI 760



 Score = 39.9 bits (89), Expect = 0.41
 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 3/91 (3%)

Query: 204  LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNV 262
            +++  + +V      +   CR  G P P  +WR+   G NM    R  +  +G+L +   
Sbjct: 1179 IVSFSQRIVTPWKEHLELPCRKVGAPAPVTIWRQD--GHNMETSARKTIAKNGTLYMKEC 1236

Query: 263  ILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
              +D G Y+C  EN+ G       + V  PP
Sbjct: 1237 QASDAGNYTCSVENTWGKDEIVYNIVVKVPP 1267



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 16/69 (23%), Positives = 35/69 (50%), Gaps = 3/69 (4%)

Query: 134  GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
            G+P P   W+++G  +  +  +R  +   G L +++ + +DAG Y C   N  G ++  +
Sbjct: 1202 GAPAPVTIWRQDGHNM--ETSARKTIAKNGTLYMKECQASDAGNYTCSVENTWG-KDEIV 1258

Query: 194  ATLKIHIKP 202
              + + + P
Sbjct: 1259 YNIVVKVPP 1267


>UniRef50_Q58EX2 Cluster: Protein sidekick-2 precursor; n=19;
           Euteleostomi|Rep: Protein sidekick-2 precursor - Homo
           sapiens (Human)
          Length = 2170

 Score =  148 bits (359), Expect = 8e-34
 Identities = 198/813 (24%), Positives = 318/813 (39%), Gaps = 91/813 (11%)

Query: 34  RAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG- 92
           R    P P + W++ G   +  + R+I     L  L      V  DAG Y+ +A N    
Sbjct: 136 RIASFPQPQVTWFRDG-RKIPPSSRAITLENTLVILST----VAPDAGRYYVQAVNDKNG 190

Query: 93  -TARSRNATLHVAV------LREEFRLEPESKQSAQGDT-VVLECLP-PRGSPEPNVYWK 143
               S+  TL V V      +     + P++     G + V LEC+   R   + ++ WK
Sbjct: 191 DNKTSQPITLTVEVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWK 250

Query: 144 KNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI--ATLKIHIK 201
           K+G  +L  G    H      L I +   +DAG Y+C A   + +  S +  A L +   
Sbjct: 251 KDG--VLLSGGISDH---NRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEP 305

Query: 202 PYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP-LGRVKVLDDGSLRL 259
           P  +  PE  + A+    V   C+  G P P + W + A    +  L R +  +DG L++
Sbjct: 306 PQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQI 365

Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLSPNSVNVESGNVARFTCTATG 318
             ++  D G + C A N+ G V  S YL V    P+I   P    V  G      C  +G
Sbjct: 366 SGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSG 425

Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
            P P + W  +G R +    +   ++  T +  G   L I+ T  +D+  T  C A N  
Sbjct: 426 APRPAITWQ-KGERILASGSVQLPRF--TPLESGS--LLISPTHISDA-GTYTCLATNSR 479

Query: 379 GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA--WYFEGE 436
           G       L V +        IT  P +Q++   + A   C     P   I   W  +G 
Sbjct: 480 GVDEASADLVVWARTR-----ITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGA 534

Query: 437 AL-IQNHRR-NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHF 494
            L  ++H R  +  +G+L +      D GTYTC   S  G    S  L            
Sbjct: 535 TLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHL------------ 582

Query: 495 FRAADVSSLPGPPTKPIT--HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNN 552
                V  LP  P  P+     V   ++ L+W++    G+S ++ Y +E      +S NN
Sbjct: 583 ----RVRQLPHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILE------MSENN 631

Query: 553 TPRNSRGWVVIARRV--HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDD 610
            P     W V+   V    T   VK L+P  +Y F +   N  G    S  ++ V++ ++
Sbjct: 632 AP-----WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEE 686

Query: 611 SNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRP 670
             +      +++         T+  + +    P +S    ++   +  Y L GL      
Sbjct: 687 PPTAPPQNVIASGR-------TNQSIMIQWQPPPESHQNGILKGYIIRYCLAGL------ 733

Query: 671 LDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDV 730
                + Y+ K I  + DV+   +  L  +T YE  +  +     G  S+     TL  V
Sbjct: 734 ----PVGYQFKNITDA-DVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGV 788

Query: 731 PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH 790
           P  PP N+     N+TT+   W+ P  Q  NGI  GY ++    +     +MV       
Sbjct: 789 PTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQ 848

Query: 791 QATSL-IMTNLTSGVSYSVQIAAETIIGLGPFS 822
            +  +  ++ L     Y   +   T  G GP S
Sbjct: 849 DSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRS 881



 Score =  127 bits (306), Expect = 2e-27
 Identities = 101/332 (30%), Positives = 142/332 (42%), Gaps = 22/332 (6%)

Query: 11  APYIIEQPLDVTV-ARHQPATLNCRAGGSPSPAIR--WYKGGVLV---VSDTHRSILPAG 64
           AP II  P + +V A     TL C A   P   +   W K GVL+   +SD +R +    
Sbjct: 212 APTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGISDHNRRL---- 267

Query: 65  GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGD 123
                        SDAG Y CEA     +  S     +++VL   +F  EPE   +A+ +
Sbjct: 268 ------TIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEME 321

Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
            VV      +G P P++ W K+   +  +  +R    + G L I      D G +QC AR
Sbjct: 322 KVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFAR 381

Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR---RSAG 240
           NAAG  +++       I P +  GP D     G SV   C   G P P + W+   R   
Sbjct: 382 NAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILA 441

Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
            G++ L R   L+ GSL +    ++D G Y+C A NS G   AS  L V+    I   P 
Sbjct: 442 SGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQ 501

Query: 301 SVNVESGNVARFTCTATGRPEPTM--FWSVEG 330
             +V  G  A   C  T  P  T+   W  +G
Sbjct: 502 DQSVIKGTQASMVCGVTHDPRVTIRYIWEKDG 533



 Score =  103 bits (248), Expect = 2e-20
 Identities = 81/298 (27%), Positives = 133/298 (44%), Gaps = 17/298 (5%)

Query: 5   YVTSGEAPYIIEQP-LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD--THRSIL 61
           Y++  E P  +++P   +T    +   + C+A G P P+I WYK   +V  +  T     
Sbjct: 299 YLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQR 358

Query: 62  PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
             GGL       G V  D G++ C A N+ G  ++ +  L V  +       P       
Sbjct: 359 NDGGL----QISGLVPDDTGMFQCFARNAAGEVQT-STYLAVTSIAPNITRGPLDSTVID 413

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGD---SRMHLVDGGNLVIQDARQTDAGRY 178
           G +VVL C    G+P P + W+K G+ +L  G     R   ++ G+L+I     +DAG Y
Sbjct: 414 GMSVVLAC-ETSGAPRPAITWQK-GERILASGSVQLPRFTPLESGSLLISPTHISDAGTY 471

Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV--LWR 236
            C+A N+ G  E++ A L +  +  +   P+D     G+  +  C V  DP   +  +W 
Sbjct: 472 TCLATNSRGVDEAS-ADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWE 530

Query: 237 RSAGG-GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
           +     G     R+++  +GSL +      D G Y+C   ++ G  S S +L V   P
Sbjct: 531 KDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLP 588



 Score = 75.4 bits (177), Expect = 9e-12
 Identities = 67/208 (32%), Positives = 91/208 (43%), Gaps = 15/208 (7%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR----SILPAGGL 66
           AP I   PLD TV       L C   G+P PAI W KG  ++ S + +    + L +G L
Sbjct: 399 APNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSL 458

Query: 67  FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
             +  TH    SDAG Y C ATNS G   + +A L V   R      P+ +   +G    
Sbjct: 459 L-ISPTH---ISDAGTYTCLATNSRGVDEA-SADL-VVWARTRITKPPQDQSVIKGTQAS 512

Query: 127 LECLPPRGSPEPNVY-WKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
           + C           Y W+K+G TL  +   R+ L   G+L I      D G Y C   +A
Sbjct: 513 MVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISA 572

Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVA 213
            G  +S  A L++   P+    PE  VA
Sbjct: 573 GG-NDSRSAHLRVRQLPH---APEHPVA 596



 Score = 74.5 bits (175), Expect = 2e-11
 Identities = 84/329 (25%), Positives = 142/329 (43%), Gaps = 26/329 (7%)

Query: 504  PGPPTKPITH--NVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV 561
            P PP++P+    +V   SV LSW   +  G S +  Y ++  +RE  SG         W 
Sbjct: 1398 PQPPSRPMVQQEDVRARSVLLSWEPGSD-GLSPVRYYTIQ--TRELPSGR--------WA 1446

Query: 562  VIARRV--HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV----GDDSNSLW 615
            + +  V  + + ++V  L P  +Y F V+  N  G S  S  S+S+T      D++ ++ 
Sbjct: 1447 LHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTIL 1506

Query: 616  EGTG-VSNSTEYR-NNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDN 673
              T   + S   R      D I  ++    I  +  +L++E L  + L G+         
Sbjct: 1507 SVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYR--ELLYEGLRGFTLRGINNPGATWAE 1564

Query: 674  ITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDG 733
            +T  Y M+ +   + ++ +E+ +L K+ +YE  +  +    EG  S  +     + VP  
Sbjct: 1565 LTSMYSMRNLSRPS-LTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTA 1623

Query: 734  PPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT 793
             P N+ +     T + + W PP L  QNG I GY +   W +         + T      
Sbjct: 1624 APRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYF-W-EAQRGNLTERVKTLFLAEN 1681

Query: 794  SLIMTNLTSGVSYSVQIAAETIIGLGPFS 822
            S+ + NLT   +Y V +AA    G GP S
Sbjct: 1682 SVKLKNLTGYTAYMVSVAAFNAAGDGPRS 1710



 Score = 70.5 bits (165), Expect = 3e-10
 Identities = 101/403 (25%), Positives = 159/403 (39%), Gaps = 48/403 (11%)

Query: 110 FRLEPESKQ-SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL-FDGDSRMHLVDGGNLVI 167
           F+ EP   Q   +G+ +VL C+   GS      W  N + L  F  + R         +I
Sbjct: 28  FKTEPVRTQVHLEGNRLVLTCMA-EGSWPLEFKWLHNNRELTKFSLEYRY--------MI 78

Query: 168 QDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC-RVG 226
               +T AG Y+CI RN  G        +++        G +      G +   +  R+ 
Sbjct: 79  TSLDRTHAGFYRCIVRNRMGALLQRQTEVQVADMGSFEEGEKHQSVSHGEAAVIRAPRIA 138

Query: 227 GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY 286
             P P V W R   G  +P     +  + +L + + +  D G Y  +A N     + +  
Sbjct: 139 SFPQPQVTWFRD--GRKIPPSSRAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQ 196

Query: 287 ---LTVY-----DP--PSINLSPNSVNVESG-NVARFTCTATGRP--EPTMFWSVEGNRT 333
              LTV      DP  P+I + P + +V +G +     C A  RP  +  + W  +G   
Sbjct: 197 PITLTVEVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDG--- 253

Query: 334 IIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGS--SFVRGKLTVTS 391
           ++  G          + D    LTI +   +D+     C AV  + S  S VRG      
Sbjct: 254 VLLSG---------GISDHNRRLTIPNPTGSDA-GYYECEAVLRSSSVPSVVRGAYLSVL 303

Query: 392 DDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRR-NVTND 449
           +   PP  +     + T  ++ +   PC A   P P I WY +   + ++   R    ND
Sbjct: 304 E---PPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRND 360

Query: 450 GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
           G L +  L   D+G + C A +  G+   S  L V S I PNI
Sbjct: 361 GGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTS-IAPNI 402



 Score = 66.1 bits (154), Expect = 6e-09
 Identities = 46/151 (30%), Positives = 69/151 (45%), Gaps = 6/151 (3%)

Query: 683  ILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQ-TLDDVPDGPPINIEMF 741
            ++  N     ++T L KY  YE  ++ F +  +G PS+  + + TLDDVP GPP+ I   
Sbjct: 1250 LVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVP-GPPMGILFP 1308

Query: 742  ILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLT 801
             + TT+V L W PP     NGII  Y +        AN + V +      A     T L 
Sbjct: 1309 EVRTTSVRLIWQPP--AAPNGIILAYQITHRLNTTTANTATVEV--LAPSARQYTATGLK 1364

Query: 802  SGVSYSVQIAAETIIGLGPFSQKVYFNIDSR 832
                Y  +I A+T  G G  ++ +    + R
Sbjct: 1365 PESVYLFRITAQTRKGWGEAAEALVVTTEKR 1395



 Score = 54.0 bits (124), Expect = 2e-05
 Identities = 43/156 (27%), Positives = 70/156 (44%), Gaps = 8/156 (5%)

Query: 661  LEGLFIYFRPLDNITIEYEMKTI-LHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPS 719
            ++G  IYF       +   +KT+ L  N V   ++ +L  YT Y   +  F    +G  S
Sbjct: 1654 IQGYKIYFWEAQRGNLTERVKTLFLAENSV---KLKNLTGYTAYMVSVAAFNAAGDGPRS 1710

Query: 720  NSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVN-WLDVPA 778
                 QT    P  P  +++   L TT+V++ W  P  Q  NGI+ GY +V      V  
Sbjct: 1711 TPTQGQTQQAAPSAPS-SVKFSELTTTSVNVSWEAP--QFPNGILEGYRLVYEPCSPVDG 1767

Query: 779  NKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAET 814
               +V ++   +    L + +L  GV+Y  +I A+T
Sbjct: 1768 VSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKT 1803



 Score = 53.2 bits (122), Expect = 4e-05
 Identities = 48/192 (25%), Positives = 93/192 (48%), Gaps = 17/192 (8%)

Query: 639 IEATPIDSKTIKLMWEILNFYYLEGL-----FIYFRPL--DNITIEYEMKTILHSNDVSG 691
           + A   +S TI+  W   +  ++ G+      I + P   + +T+         S  V G
Sbjct: 796 VHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHV-G 854

Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751
           F ++ L+K+T+Y   ++ F    +G  S  ++ +T +DVP GP  ++    +  T++ + 
Sbjct: 855 F-VSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVP-GPVGHLSFSEILDTSLKVS 912

Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT-SLIMTNLTSGVSYSVQI 810
           W  P    +NGI+TGY   ++W +   N++   +   +   T    +T LT+  +Y++++
Sbjct: 913 WQEP--GEKNGILTGYR--ISWEEY--NRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEV 966

Query: 811 AAETIIGLGPFS 822
           AA T  G G  S
Sbjct: 967 AAMTSKGQGQVS 978



 Score = 52.0 bits (119), Expect = 1e-04
 Identities = 40/141 (28%), Positives = 59/141 (41%), Gaps = 5/141 (3%)

Query: 688  DVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN-SRVAQTLDDVPDGPPINIEMFILNTT 746
            D    E+  L  +T Y F +          PS  SR  QTL   PD  P N+ +   + T
Sbjct: 1050 DARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASET 1109

Query: 747  TVHLKWSP-PELQLQ-NGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGV 804
            ++ L+W P PE++   N    GY +  +  D         +   V +     + +L    
Sbjct: 1110 SLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVER--DYTIEDLEEWT 1167

Query: 805  SYSVQIAAETIIGLGPFSQKV 825
             Y VQ+ A   IG GP+SQ V
Sbjct: 1168 EYRVQVQAFNAIGSGPWSQTV 1188



 Score = 50.8 bits (116), Expect = 2e-04
 Identities = 33/124 (26%), Positives = 56/124 (45%), Gaps = 3/124 (2%)

Query: 703 YEFFLIPFYKKFEGKPSNSRVAQTL-DDVPDGPPINIEMFILNTTTVHLKWSPPELQLQN 761
           Y+F L       +G+ S      +L ++ P  PP N+        ++ ++W PP    QN
Sbjct: 659 YQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQN 718

Query: 762 GIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPF 821
           GI+ GY +      +P        N T     +L++ +L    +Y +++AA    GLG +
Sbjct: 719 GILKGYIIRYCLAGLPVGYQFK--NITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVY 776

Query: 822 SQKV 825
           S KV
Sbjct: 777 SSKV 780



 Score = 49.2 bits (112), Expect = 7e-04
 Identities = 33/128 (25%), Positives = 57/128 (44%), Gaps = 2/128 (1%)

Query: 692  FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751
            + I  L ++T+Y   +  F     G  S + V +T + VP   P N+      ++++ ++
Sbjct: 1158 YTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVR 1217

Query: 752  WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811
            WS      +NG++ GY V+    D         +    + + S  +T L   V Y VQ+ 
Sbjct: 1218 WSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEG--NSSRSAQLTGLGKYVLYEVQVL 1275

Query: 812  AETIIGLG 819
            A T IG G
Sbjct: 1276 AFTRIGDG 1283


>UniRef50_UPI0000E80BF7 Cluster: PREDICTED: similar to bone specific
            CMF608; n=2; Gallus gallus|Rep: PREDICTED: similar to
            bone specific CMF608 - Gallus gallus
          Length = 1817

 Score =  148 bits (358), Expect = 1e-33
 Identities = 174/631 (27%), Positives = 266/631 (42%), Gaps = 66/631 (10%)

Query: 12   PYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWY--KGGV---LVVSDTHRSILPAGG 65
            P I+E+    +     Q   L C A G+P P + W   KG     L   +T   +LP G 
Sbjct: 1036 PIILEEKRQQIAATAGQDLNLPCTAEGNPQPHVHWVLSKGTAVKPLQFVNTRVLLLPNGT 1095

Query: 66   LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---G 122
            L         V +D+G Y C AT+S G+ R R   L V       R+   S+   Q   G
Sbjct: 1096 L----QLSSIVPADSGNYECIATSSTGSER-RVVILTVRHRDTLPRIAAASQGMTQLSFG 1150

Query: 123  DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGD---SRMHLVDGGNLVIQDARQTDAGRYQ 179
            D ++L C    G P+P + W+   + ++       SR+H+   G+LVI+   + DAG Y 
Sbjct: 1151 DKLLLNCTAT-GEPQPRIMWRLPSKAVVDQWHRMGSRIHVYPNGSLVIEAVTEKDAGDYL 1209

Query: 180  CIARNAAGTRESAIATLKIHIKPYLITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
            C+ARN  G  +  +  + I +KP  I   +    +   G      C+  G P P++ W  
Sbjct: 1210 CVARNKIGD-DLILMKVSITMKPAKIDQKQYFKKLVPYGKDFQVDCKASGSPAPEISWSL 1268

Query: 238  SAGG--GNMPLG--------RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYL 287
              G    N  L         R  + D+G+L L+   + +EG+Y+C A+NS+G      ++
Sbjct: 1269 PDGMVINNAMLADDSGHRARRYVLFDNGTLYLNRAGVTEEGDYTCYAQNSLGRDEMKIHV 1328

Query: 288  TVYDP-PSINLSPNS-VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345
            TV    P I  S  + V V++G+ A   C A G P+P +FW +  +  I     S D+ H
Sbjct: 1329 TVVTAAPQIKHSYKTYVKVKAGDTALLDCEAAGEPKPKIFWLLPSSDII---SSSTDR-H 1384

Query: 346  ATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPS 405
               V   ++V      D  +     +C A N  G      KL V    D  PPII    +
Sbjct: 1385 LLHVNGSLSVRRAKLLDAGE----YMCVARNAGGDDTKLYKLDV----DAKPPIINGLYT 1436

Query: 406  NQTLPIKSMAV------FPCTAICTPEPIIAWYFEGEALIQ----NHRRNVTNDGTLVLK 455
            N+T+ IK  AV        C A  TP P I W       +       R  +  +GTL ++
Sbjct: 1437 NKTI-IKVTAVRHSKKQIDCRAEGTPPPQIMWIMPDNIFLTAPYYGSRIVIHKNGTLEIR 1495

Query: 456  DLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNV 515
            +L  SD+  + CVA +  G+ V    L V   +   +  F+      +   P K IT N 
Sbjct: 1496 NLRPSDTADFICVARNDWGESVLVVRLEVLEMLRRPM--FKNPFNEKIIAKPGKTITLNC 1553

Query: 516  T---DTSVTLSWSQNNKIGSSSILGY-QVEVFSRETLSGNNTPRNSRGWVVIARRVHQTH 571
            +   +    +SW   N +  S   G  +    S  TLS  N  R+  G    A + +Q  
Sbjct: 1554 SVDGNPPPEVSWMLPNGMWLSKGTGTPEFLPGSNGTLSIRNPSRDKAGKYRCAAK-NQVG 1612

Query: 572  YVVKSLIPGITYMFIVRTENS---HGLSGPS 599
            Y+ K ++  +     + T       G+SG S
Sbjct: 1613 YIEKLIVLEVAQKPTILTHPKGPMRGISGES 1643



 Score =  146 bits (354), Expect = 3e-33
 Identities = 131/480 (27%), Positives = 192/480 (40%), Gaps = 40/480 (8%)

Query: 22   TVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSDTHRSILPAGGLFFLRATHGRVHS 78
            TV  +  A + C A G+P P I W K         S +  ++LP G L   +A       
Sbjct: 856  TVLANSDAFIPCEATGNPQPTIEWTKMSPDTDAPASGSRWTVLPNGTLAIAQA----ALQ 911

Query: 79   DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
            D G Y C ATN  GTAR   ATL V               +  G  V + C P  G P P
Sbjct: 912  DGGQYRCTATNVLGTARLL-ATLAVVAYPPRIAGSTRLLTAHAGMPVAMRC-PAEGRPPP 969

Query: 139  NVYW-KKNGQ--TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195
            ++ W   NG   +    G+ ++ +   G L I+D    D G Y C A N AGT    +  
Sbjct: 970  SISWVLANGTHVSSSSQGNQKVLVRPDGTLTIKDVTVYDRGLYTCTATNPAGTDALTVKL 1029

Query: 196  LKIHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL----GRVK 250
              I   P ++      +A T G  +   C   G+P P V W  S G    PL     RV 
Sbjct: 1030 QVIAAPPIILEEKRQQIAATAGQDLNLPCTAEGNPQPHVHWVLSKGTAVKPLQFVNTRVL 1089

Query: 251  VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD----PPSINLSPNSVNVES 306
            +L +G+L+L +++ AD G Y C A +S G+      LTV      P     S     +  
Sbjct: 1090 LLPNGTLQLSSIVPADSGNYECIATSSTGSERRVVILTVRHRDTLPRIAAASQGMTQLSF 1149

Query: 307  GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
            G+     CTATG P+P + W +     +        + H       + +  + + D  D 
Sbjct: 1150 GDKLLLNCTATGEPQPRIMWRLPSKAVVDQWHRMGSRIHVYP-NGSLVIEAVTEKDAGD- 1207

Query: 367  RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
                +C A N  G   +  K+++T    +P  I       + +P        C A  +P 
Sbjct: 1208 ---YLCVARNKIGDDLILMKVSITM---KPAKIDQKQYFKKLVPYGKDFQVDCKASGSPA 1261

Query: 427  PIIAWYFEGEALIQN--------HRRN---VTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
            P I+W      +I N        HR     + ++GTL L     ++ G YTC A +  G+
Sbjct: 1262 PEISWSLPDGMVINNAMLADDSGHRARRYVLFDNGTLYLNRAGVTEEGDYTCYAQNSLGR 1321



 Score =  130 bits (313), Expect = 3e-28
 Identities = 127/477 (26%), Positives = 199/477 (41%), Gaps = 38/477 (7%)

Query: 21   VTVARHQPATLNCRAGGSPSPAIRWY-KGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
            V V     A L+C A G P P I W      ++ S T R +L   G   +R        D
Sbjct: 1345 VKVKAGDTALLDCEAAGEPKPKIFWLLPSSDIISSSTDRHLLHVNGSLSVRRAK---LLD 1401

Query: 80   AGVYWCEATNSYGTARSR---NATLHVAVLREEFRLEPESKQSA-QGDTVVLECLPPRGS 135
            AG Y C A N+ G        +      ++   +  +   K +A +     ++C    G+
Sbjct: 1402 AGEYMCVARNAGGDDTKLYKLDVDAKPPIINGLYTNKTIIKVTAVRHSKKQIDCRA-EGT 1460

Query: 136  PEPNVYWKKNGQTLLFDG--DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
            P P + W       L      SR+ +   G L I++ R +D   + C+ARN  G     +
Sbjct: 1461 PPPQIMWIMPDNIFLTAPYYGSRIVIHKNGTLEIRNLRPSDTADFICVARNDWGESVLVV 1520

Query: 194  A--TLKIHIKPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG-NMPLGR 248
                L++  +P +   P  E ++A+ G ++T  C V G+P P+V W    G   +   G 
Sbjct: 1521 RLEVLEMLRRP-MFKNPFNEKIIAKPGKTITLNCSVDGNPPPEVSWMLPNGMWLSKGTGT 1579

Query: 249  VKVL--DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS-VNVE 305
             + L   +G+L + N      G+Y C A+N VG +     L V   P+I   P   +   
Sbjct: 1580 PEFLPGSNGTLSIRNPSRDKAGKYRCAAKNQVGYIEKLIVLEVAQKPTILTHPKGPMRGI 1639

Query: 306  SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
            SG      C + G P+P+  W++ G   +      R + ++  +      L I     +D
Sbjct: 1640 SGESLSLHCLSDGSPKPSTAWTLPGGHVL-----DRPQINSRHILLENGTLVIRAATIHD 1694

Query: 366  SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICT 424
             R   VC A N AG   +   +T+ +     PP ITN P      +   AV   CTA+  
Sbjct: 1695 -RGNYVCRAHNPAGDFSITIPVTIVAY----PPRITNRPPQTIHTMPGAAVQLSCTALGI 1749

Query: 425  PEPIIAWYFEGEALIQ--NHRRNVTND-----GTLVLKDLDKSDSGTYTCVASSRHG 474
            P P I W     +++   NH R   ++     GTL +++   SDSGTY C A +  G
Sbjct: 1750 PRPEITWELPDHSILSTGNHGRASGSELLHPQGTLRIQNPQPSDSGTYKCTARNHLG 1806



 Score =  125 bits (302), Expect = 6e-27
 Identities = 100/377 (26%), Positives = 166/377 (44%), Gaps = 21/377 (5%)

Query: 19   LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTH---RSILPAGGLFFLRATHGR 75
            + VT  RH    ++CRA G+P P I W     + ++  +   R ++   G   +R     
Sbjct: 1441 IKVTAVRHSKKQIDCRAEGTPPPQIMWIMPDNIFLTAPYYGSRIVIHKNGTLEIRNLR-- 1498

Query: 76   VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ--SAQGDTVVLECLPPR 133
              SD   + C A N +G +        + +LR      P +++  +  G T+ L C    
Sbjct: 1499 -PSDTADFICVARNDWGESVLVVRLEVLEMLRRPMFKNPFNEKIIAKPGKTITLNC-SVD 1556

Query: 134  GSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGTRES 191
            G+P P V W       L  G      + G  G L I++  +  AG+Y+C A+N  G  E 
Sbjct: 1557 GNPPPEVSWMLPNGMWLSKGTGTPEFLPGSNGTLSIRNPSRDKAGKYRCAAKNQVGYIEK 1616

Query: 192  AIATLKIHIKPYLITGPEDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSAGGG-NMPL--G 247
             I  L++  KP ++T P+  +   +G S++  C   G P P   W    G   + P    
Sbjct: 1617 LI-VLEVAQKPTILTHPKGPMRGISGESLSLHCLSDGSPKPSTAWTLPGGHVLDRPQINS 1675

Query: 248  RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV--YDPPSINLSPNSVNVE 305
            R  +L++G+L +    + D G Y C A N  G  S +  +T+  Y P   N  P +++  
Sbjct: 1676 RHILLENGTLVIRAATIHDRGNYVCRAHNPAGDFSITIPVTIVAYPPRITNRPPQTIHTM 1735

Query: 306  SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
             G   + +CTA G P P + W +  + +I+  G +  +   + +      L I +   +D
Sbjct: 1736 PGAAVQLSCTALGIPRPEITWELP-DHSILSTG-NHGRASGSELLHPQGTLRIQNPQPSD 1793

Query: 366  SRNTIVCSAVNYAGSSF 382
            S  T  C+A N+ GS F
Sbjct: 1794 S-GTYKCTARNHLGSDF 1809



 Score =  114 bits (275), Expect = 1e-23
 Identities = 122/480 (25%), Positives = 199/480 (41%), Gaps = 56/480 (11%)

Query: 31   LNCRAGGSPSPAIRWYKGGVLVVSDT-------HRS----ILPAGGLFFLRATHGRVHSD 79
            ++C+A GSP+P I W     +V+++        HR+    +   G L+  RA      ++
Sbjct: 1252 VDCKASGSPAPEISWSLPDGMVINNAMLADDSGHRARRYVLFDNGTLYLNRAGV----TE 1307

Query: 80   AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GDTVVLECLPPRGSP 136
             G Y C A NS G    +   +HV V+    +++   K   +   GDT +L+C    G P
Sbjct: 1308 EGDYTCYAQNSLGRDEMK---IHVTVVTAAPQIKHSYKTYVKVKAGDTALLDC-EAAGEP 1363

Query: 137  EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
            +P ++W      ++     R  L   G+L ++ A+  DAG Y C+ARNA G  ++ +  L
Sbjct: 1364 KPKIFWLLPSSDIISSSTDRHLLHVNGSLSVRRAKLLDAGEYMCVARNAGGD-DTKLYKL 1422

Query: 197  KIHIKPYLITGPE------DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG-GGNMPL--G 247
             +  KP +I G         V A   S     CR  G P P ++W          P    
Sbjct: 1423 DVDAKPPIINGLYTNKTIIKVTAVRHSKKQIDCRAEGTPPPQIMWIMPDNIFLTAPYYGS 1482

Query: 248  RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD----PPSINLSPNSVN 303
            R+ +  +G+L + N+  +D  ++ C A N  G       L V +    P   N     + 
Sbjct: 1483 RIVIHKNGTLEIRNLRPSDTADFICVARNDWGESVLVVRLEVLEMLRRPMFKNPFNEKII 1542

Query: 304  VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF--DGVTVLTINDT 361
             + G      C+  G P P + W +         GM   K   T  F       L+I + 
Sbjct: 1543 AKPGKTITLNCSVDGNPPPEVSWMLPN-------GMWLSKGTGTPEFLPGSNGTLSIRNP 1595

Query: 362  DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCT 420
             + D      C+A N  G  ++  KL V  +  + P I+T+ P      I   ++   C 
Sbjct: 1596 SR-DKAGKYRCAAKNQVG--YIE-KLIVL-EVAQKPTILTH-PKGPMRGISGESLSLHCL 1649

Query: 421  AICTPEPIIAWYFEGEALIQ----NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476
            +  +P+P  AW   G  ++     N R  +  +GTLV++     D G Y C A +  G +
Sbjct: 1650 SDGSPKPSTAWTLPGGHVLDRPQINSRHILLENGTLVIRAATIHDRGNYVCRAHNPAGDF 1709



 Score =  111 bits (267), Expect = 1e-22
 Identities = 122/478 (25%), Positives = 195/478 (40%), Gaps = 36/478 (7%)

Query: 21   VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRS-----ILPAGGLFFLRATHGR 75
            +T     P  + C A G P P+I W       VS + +      + P G L     T   
Sbjct: 949  LTAHAGMPVAMRCPAEGRPPPSISWVLANGTHVSSSSQGNQKVLVRPDGTLTIKDVT--- 1005

Query: 76   VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA--QGDTVVLECLPPR 133
            V+ D G+Y C ATN  GT  +    L V +      LE + +Q A   G  + L C    
Sbjct: 1006 VY-DRGLYTCTATNPAGT-DALTVKLQV-IAAPPIILEEKRQQIAATAGQDLNLPC-TAE 1061

Query: 134  GSPEPNVYW---KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT-R 189
            G+P+P+V+W   K      L   ++R+ L+  G L +      D+G Y+CIA ++ G+ R
Sbjct: 1062 GNPQPHVHWVLSKGTAVKPLQFVNTRVLLLPNGTLQLSSIVPADSGNYECIATSSTGSER 1121

Query: 190  ESAIATLKIHIKPYLITGPEDVVAQT--GSSVTFQCRVGGDPLPDVLWRRSAGG----GN 243
               I T++       I      + Q   G  +   C   G+P P ++WR  +       +
Sbjct: 1122 RVVILTVRHRDTLPRIAAASQGMTQLSFGDKLLLNCTATGEPQPRIMWRLPSKAVVDQWH 1181

Query: 244  MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV-YDPPSINLSPNSV 302
                R+ V  +GSL ++ V   D G+Y C A N +G       +++   P  I+      
Sbjct: 1182 RMGSRIHVYPNGSLVIEAVTEKDAGDYLCVARNKIGDDLILMKVSITMKPAKIDQKQYFK 1241

Query: 303  N-VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT---AVFDGVTVLTI 358
              V  G   +  C A+G P P + WS+     I    ++ D  H      +FD  T L +
Sbjct: 1242 KLVPYGKDFQVDCKASGSPAPEISWSLPDGMVINNAMLADDSGHRARRYVLFDNGT-LYL 1300

Query: 359  NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
            N     +      C A N  G   ++  +TV +     P I  +  +   +     A+  
Sbjct: 1301 NRAGVTE-EGDYTCYAQNSLGRDEMKIHVTVVT---AAPQIKHSYKTYVKVKAGDTALLD 1356

Query: 419  CTAICTPEPIIAWYFEGEALIQN--HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
            C A   P+P I W      +I +   R  +  +G+L ++     D+G Y CVA +  G
Sbjct: 1357 CEAAGEPKPKIFWLLPSSDIISSSTDRHLLHVNGSLSVRRAKLLDAGEYMCVARNAGG 1414



 Score = 89.4 bits (212), Expect = 5e-16
 Identities = 77/272 (28%), Positives = 109/272 (40%), Gaps = 17/272 (6%)

Query: 30   TLNCRAGGSPSPAIRWY-KGGVLVVSDTHR-SILP-AGGLFFLRATHGRVHSDAGVYWCE 86
            TLNC   G+P P + W    G+ +   T     LP + G   +R         AG Y C 
Sbjct: 1550 TLNCSVDGNPPPEVSWMLPNGMWLSKGTGTPEFLPGSNGTLSIRNPS---RDKAGKYRCA 1606

Query: 87   ATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146
            A N  G    +   L VA             +   G+++ L CL   GSP+P+  W   G
Sbjct: 1607 AKNQVGYIE-KLIVLEVAQKPTILTHPKGPMRGISGESLSLHCLSD-GSPKPSTAWTLPG 1664

Query: 147  QTLLFDG--DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL 204
              +L     +SR  L++ G LVI+ A   D G Y C A N AG     I    +   P +
Sbjct: 1665 GHVLDRPQINSRHILLENGTLVIRAATIHDRGNYVCRAHNPAGDFSITIPVTIVAYPPRI 1724

Query: 205  ITGPEDVV-AQTGSSVTFQCRVGGDPLPDVLWR------RSAGGGNMPLGRVKVLDDGSL 257
               P   +    G++V   C   G P P++ W        S G      G   +   G+L
Sbjct: 1725 TNRPPQTIHTMPGAAVQLSCTALGIPRPEITWELPDHSILSTGNHGRASGSELLHPQGTL 1784

Query: 258  RLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
            R+ N   +D G Y C A N +G+     Y+ V
Sbjct: 1785 RIQNPQPSDSGTYKCTARNHLGSDFTVTYIHV 1816



 Score = 61.3 bits (142), Expect = 2e-07
 Identities = 42/170 (24%), Positives = 74/170 (43%), Gaps = 9/170 (5%)

Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
           G   +  C A G P P + W +     +  P +S D      V  G   L   DT     
Sbjct: 524 GGTVQLDCQAIGEPAPAIEWILADGSKVRAPYVSEDG-RIIVVKSGTFTLRTADTFDTGL 582

Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
            +   C   NY  +  +  ++TV   D        NG +  +  + S+   PCT+   P+
Sbjct: 583 YH---CIGTNYNDADILTFRITVV--DPYVEHSSVNG-AQLSAAVGSILDLPCTSTAVPD 636

Query: 427 PIIAWYFEGEALIQNHRRN--VTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
             ++W      ++ +  RN  + ++GTL ++ + + DSG + CVA+S++G
Sbjct: 637 AAVSWVLPERVVLHHSVRNRHIFDNGTLRIQGVTERDSGYFRCVAASQYG 686



 Score = 55.2 bits (127), Expect = 1e-05
 Identities = 47/163 (28%), Positives = 67/163 (41%), Gaps = 11/163 (6%)

Query: 31  LNCRAGGSPSPAIRWY-----KGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85
           L+C+A G P+PAI W      K     VS+  R I+   G F LR        D G+Y C
Sbjct: 529 LDCQAIGEPAPAIEWILADGSKVRAPYVSEDGRIIVVKSGTFTLRTADT---FDTGLYHC 585

Query: 86  EATNSYGTARSRNATLHVA-VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK 144
             TN Y  A      + V     E   +      +A G  + L C      P+  V W  
Sbjct: 586 IGTN-YNDADILTFRITVVDPYVEHSSVNGAQLSAAVGSILDLPCTST-AVPDAAVSWVL 643

Query: 145 NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
             + +L       H+ D G L IQ   + D+G ++C+A +  G
Sbjct: 644 PERVVLHHSVRNRHIFDNGTLRIQGVTERDSGYFRCVAASQYG 686



 Score = 49.6 bits (113), Expect = 5e-04
 Identities = 49/193 (25%), Positives = 80/193 (41%), Gaps = 15/193 (7%)

Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGG-NMPL----GRVKVLDDGSLRLDNVILADEGEY 270
           G +V   C+  G+P P + W  + G     P     GR+ V+  G+  L      D G Y
Sbjct: 524 GGTVQLDCQAIGEPAPAIEWILADGSKVRAPYVSEDGRIIVVKSGTFTLRTADTFDTGLY 583

Query: 271 SCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES--GNVARFTCTATGRPEPTMFWSV 328
            C   N   A   +  +TV DP   + S N   + +  G++    CT+T  P+  + W V
Sbjct: 584 HCIGTNYNDADILTFRITVVDPYVEHSSVNGAQLSAAVGSILDLPCTSTAVPDAAVSW-V 642

Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT 388
              R ++   + R+++    +FD  T L I    + DS     C A +  G   +  ++ 
Sbjct: 643 LPERVVLHHSV-RNRH----IFDNGT-LRIQGVTERDS-GYFRCVAASQYGVDLLVFQVL 695

Query: 389 VTSDDDRPPPIIT 401
           V  D   P  + T
Sbjct: 696 VRKDKSTPQEVPT 708



 Score = 43.6 bits (98), Expect = 0.034
 Identities = 44/168 (26%), Positives = 69/168 (41%), Gaps = 15/168 (8%)

Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTL---LFDGDSRMHLVDGGNLVIQDARQTDAGR 177
           G TV L+C    G P P + W   +G  +       D R+ +V  G   ++ A   D G 
Sbjct: 524 GGTVQLDC-QAIGEPAPAIEWILADGSKVRAPYVSEDGRIIVVKSGTFTLRTADTFDTGL 582

Query: 178 YQCIARNAAGTRESAIATLKIHI-KPYL----ITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
           Y CI  N     ++ I T +I +  PY+    + G + + A  GS +   C     P   
Sbjct: 583 YHCIGTNY---NDADILTFRITVVDPYVEHSSVNGAQ-LSAAVGSILDLPCTSTAVPDAA 638

Query: 233 VLWRRSAGGG-NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279
           V W        +  +    + D+G+LR+  V   D G + C A +  G
Sbjct: 639 VSWVLPERVVLHHSVRNRHIFDNGTLRIQGVTERDSGYFRCVAASQYG 686



 Score = 36.3 bits (80), Expect = 5.1
 Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 3/78 (3%)

Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF---EGEALIQNHRRNVTNDGTLV 453
           P II    +  T+   S A  PC A   P+P I W     + +A     R  V  +GTL 
Sbjct: 845 PRIIGGKLAAFTVLANSDAFIPCEATGNPQPTIEWTKMSPDTDAPASGSRWTVLPNGTLA 904

Query: 454 LKDLDKSDSGTYTCVASS 471
           +      D G Y C A++
Sbjct: 905 IAQAALQDGGQYRCTATN 922


>UniRef50_UPI0000D56997 Cluster: PREDICTED: similar to CG8581-PA,
           isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG8581-PA, isoform A - Tribolium castaneum
          Length = 1429

 Score =  147 bits (357), Expect = 1e-33
 Identities = 202/834 (24%), Positives = 323/834 (38%), Gaps = 81/834 (9%)

Query: 8   SGEAPYIIEQPLDVTVARHQPATLNC--RAGGSPSPAIRWY---KGGVLVVSDTHRSILP 62
           SG       +P D  V   Q A L+C  ++    S  I+W    +  +  + D +RS L 
Sbjct: 2   SGHVLEFTVEPTDTVVESGQSAVLDCVIKSSHPASVLIQWLDQDRQKLTYLGDLYRSQLT 61

Query: 63  AGGLFFLRATHGRVHSDAGVYWCEAT-NSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
            G L+       +  +  G Y C A+  + G+  S+ ATL+VA +   F  EP   +  +
Sbjct: 62  NGSLYINSVLEEQRLT--GTYQCMASLPNVGSIVSKAATLNVASI-SGFLEEPRDLRVYE 118

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
           G      C     +P   + W K+ + L  D + RM L+  G L I +  ++D G Y+C 
Sbjct: 119 GQRAHFACHVV-AAPPAKIRWLKDERPLQID-ELRMTLLPSGALEIDEVAESDQGAYRCN 176

Query: 182 ARNAAGTRESAIATLKIH--------IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233
           A      + S  ATL +         + P  I  P+  V   G +V+  C   G P P +
Sbjct: 177 ATGLNLYKLSNKATLTVSGDREEAHFVPPTFIARPKSAVVVEGQNVSLDCAANGYPHPSI 236

Query: 234 LWRRSAGGGNMPL--GRV-KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290
            W +     +M     R  KV    SLR+ N+   D G Y C A N   ++ AS  + V 
Sbjct: 237 TWLKDGSTIDMTFLDSRFSKVGSTSSLRITNIKEEDAGTYQCRAANREDSLDASATIQVQ 296

Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
            PP     P      +       C+  G PEP + W  +G   I     S D Y    + 
Sbjct: 297 VPPRFRKKPQDKIENANKDIELECSVYGNPEPKISWFKDGEAII-----SNDYYQ---IV 348

Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
           +G   L I     +DS     C A N AG+      L V +     P        N+  P
Sbjct: 349 NGHN-LKIMGLMPSDS-GIFQCFASNPAGNIQAAASLKVLNPG---PKKRKKSKKNRDNP 403

Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470
           I  M  F   +   P+   A   + +      R+N   D +   + +       ++ + S
Sbjct: 404 IDQMQSFTLFSHLKPDSS-ARLGDVDFGHFARRKNFMQDSSSSSQTI-YDPQRAFSSLKS 461

Query: 471 SRHGKYVWSG----ALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQ 526
           S     +  G    A    S  +       A      PGPP       V    VTLSW +
Sbjct: 462 SESYDNINLGDTQHAFFPPSSTSITAESSVAKTTEGFPGPPQDLKAPIVKARFVTLSW-R 520

Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFI 586
              + S +I  Y V  + +E          SR       R+ + +  +  L P   Y F 
Sbjct: 521 APLVNSDNIHTYTV-YYRQEGSERWRVQNTSRS------RLEEIN--IAGLTPSKVYHFR 571

Query: 587 VRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDS 646
           V   NS G +G S  S+S+TV   S      +  ++   Y  +  T ++      TP + 
Sbjct: 572 VVAINSVG-AGVS--SESLTVTTQSEE-HVASAPTHFVAYATSPRTIYLNWRPPETP-NG 626

Query: 647 KTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFF 706
             ++ M      YY+E        +D   ++Y +                L  YT+Y  +
Sbjct: 627 NILRYM-----VYYMETSSSVEHNIDTTELKYHL--------------VGLSVYTEYSVW 667

Query: 707 LIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITG 766
           ++   +   G  ++ ++ +TL   P  PP NI +   +TT + ++W PP  + QNG+ITG
Sbjct: 668 VVAVNENGPGAATDEKIVRTLSASPSEPPSNITLEPTSTTVI-VRWEPPPPEYQNGVITG 726

Query: 767 YNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGP 820
           Y +          K  V + T+ ++    ++ +L  G  Y V++ A  + G  P
Sbjct: 727 YKLKYR----KQGKKGVTVTTSANE-RFYVLNDLERGAEYQVKLWAINVNGTSP 775



 Score = 51.2 bits (117), Expect = 2e-04
 Identities = 58/236 (24%), Positives = 98/236 (41%), Gaps = 14/236 (5%)

Query: 675  TIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQ-TLDDVPDG 733
            T E  M+T   +       I  L+  T YEF  +   K  +  P +  V   T +  P+ 
Sbjct: 940  TAERTMRTRTVNVSDLNVMIDDLKPNTLYEF-AVKLVKGRKESPWSMVVQNATWELAPNA 998

Query: 734  PPINIEMFILNTTT--VHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQ 791
             P ++++ +       V L W PP++   +G ITGY ++       +++  +A   T   
Sbjct: 999  SPRDLDVHLKEDEPQLVELTWQPPKIT--SGRITGYVILYTDNKTKSDREWLA-QATKGD 1055

Query: 792  ATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIV 851
              S ++ +L     Y  ++ A    G GPFS  V F   S    L   SR  ++G+  I 
Sbjct: 1056 KHSAVLGDLKPNTEYYFKVQARNSKGYGPFSNVVIFTTGSNVGTLVSSSRQHLDGK-GIF 1114

Query: 852  AGDFVMETWFYFLIGA--IVLFKIIVIAGIIYVRKYNIFAKKSALPNIYDSNGTSL 905
            +G  ++    YFLIG   I +  I V+  ++  R+ +  A        Y     S+
Sbjct: 1115 SGTVII----YFLIGGCIIAVTTIGVVTTVLCCRRRDAAASPDRSKKGYQKGNQSV 1166


>UniRef50_Q59E65 Cluster: CG33519-PB; n=5; Sophophora|Rep: CG33519-PB
            - Drosophila melanogaster (Fruit fly)
          Length = 4129

 Score =  147 bits (357), Expect = 1e-33
 Identities = 152/630 (24%), Positives = 258/630 (40%), Gaps = 60/630 (9%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL--PAGGLFFL 69
            P  ++     TV   +P  L  +  G P+P ++WYK G+L+      + +  P G +  +
Sbjct: 2229 PKFLKPITSQTVVVGEPLKLEAQVTGFPAPEVKWYKDGMLLRPSPEINFINSPNGQIGLI 2288

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARS-RNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
                     DAGVY C   N  G         +     +  F  E +   S +G  V ++
Sbjct: 2289 --IDAAQPLDAGVYKCLIANKGGEIEGVSKVEIVPKESKPVFVAELQDASSIEGFPVKMD 2346

Query: 129  CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD----GGNLVIQDARQTDAGRYQCIARN 184
             +   G+P+P + W  NG  +  D  S + +V+      +L+I+     D+G Y+ IA+N
Sbjct: 2347 -IKVVGNPKPKLQWFHNGHEIKPDA-SHIAIVENPDNSSSLIIEKTAPGDSGLYEVIAQN 2404

Query: 185  AAGTRESAIATLKIHIK---------PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
              G+  S  A L +  K         P  ++   DV A  G  +        +P+P+V+W
Sbjct: 2405 PEGSTASK-AKLYVAPKADETATEEAPQFVSALRDVNADEGQELVLSAPFISNPMPEVIW 2463

Query: 236  RRSAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSA---SGYLTV 289
             +  G    P  R+ +  DG    L +     AD G Y+C   N +G  S+   +    V
Sbjct: 2464 SKD-GVTLTPNERLLMTCDGKHIGLTIKPAEAADSGNYTCLLANPLGEDSSACNANVRKV 2522

Query: 290  YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
            Y PP      +      GN A+   T +G P P + W  +       P    +KY     
Sbjct: 2523 YKPPVFTQKISDQQQVFGNNAKIPVTVSGVPYPDLEWYFQDK-----PIPKSEKYSIKND 2577

Query: 350  FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR----PPPIITNGPS 405
             D   +L +N+ +K D +    C A N  G    +G+L + ++  +     PP+      
Sbjct: 2578 GDH-HMLIVNNCEKGD-QGVYKCIASNREGKDITQGRLDIVNEIKKHSRSEPPVFLKKIG 2635

Query: 406  NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR--RNVTNDG--TLVLKDLDKSD 461
            +  +    +A F   A   PEP + W+   + L  + R   ++  +G   L +K++ + D
Sbjct: 2636 DCDIYEGMVAKFTACATGYPEPEVEWFKNDQKLFPSDRFLIDIEPNGLLRLTIKNVTEYD 2695

Query: 462  SGTYTCVASSRHGKYVWSGALLVDS------PINPNIHFFRAADVSSLPGPPTK-PITHN 514
             G Y+C   + +G  +    L  DS      P+      F+    S  P P ++ PI   
Sbjct: 2696 VGRYSCRIFNPYGDDICHAELFYDSLDSQQKPLEDQYTDFKKYKKSGAPPPLSEGPIISR 2755

Query: 515  VTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVV 574
            +TD  + LSW+ +  +     + YQ+E+         + P     W  +   V      +
Sbjct: 2756 MTDRGLLLSWNPSVPLTPRYPITYQIEMM--------DLPEGD--WRTLRTGVRSCACDI 2805

Query: 575  KSLIPGITYMFIVRTENSHGLSGPSPVSDS 604
            ++L P   Y F VR EN  G+S PSP + +
Sbjct: 2806 RNLEPFRDYRFRVRVENKFGVSDPSPYTQT 2835



 Score =  130 bits (314), Expect = 2e-28
 Identities = 126/488 (25%), Positives = 205/488 (42%), Gaps = 45/488 (9%)

Query: 23   VARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGLFFLRATHGRVHSDAG 81
            V + +P  L C   GSP P ++W K G  V  S++ +      GL  L     + + D+G
Sbjct: 2143 VLQGEPLVLECCVDGSPLPTVQWLKDGDEVKPSESIKISTNPDGLVKLEINSCQPN-DSG 2201

Query: 82   VYWCEATNSYGTARSRNATLHVAVLREEFR---LEPESKQSAQ-GDTVVLECLPPRGSPE 137
             Y    +N +G    + A   VAV  EE +   L+P + Q+   G+ + LE     G P 
Sbjct: 2202 AYKLIISNPHG---EKVALCAVAVKPEEMQPKFLKPITSQTVVVGEPLKLEA-QVTGFPA 2257

Query: 138  PNVYWKKNGQTLLFDGDSRMHLVDGGN----LVIQDARQTDAGRYQCIARNAAGTRE--S 191
            P V W K+G  +L      ++ ++  N    L+I  A+  DAG Y+C+  N  G  E  S
Sbjct: 2258 PEVKWYKDG--MLLRPSPEINFINSPNGQIGLIIDAAQPLDAGVYKCLIANKGGEIEGVS 2315

Query: 192  AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
             +  +    KP  +   +D  +  G  V    +V G+P P + W  +          + +
Sbjct: 2316 KVEIVPKESKPVFVAELQDASSIEGFPVKMDIKVVGNPKPKLQWFHNGHEIKPDASHIAI 2375

Query: 252  LDD----GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---------DPPSINLS 298
            +++     SL ++     D G Y   A+N  G+ ++   L V          + P    +
Sbjct: 2376 VENPDNSSSLIIEKTAPGDSGLYEVIAQNPEGSTASKAKLYVAPKADETATEEAPQFVSA 2435

Query: 299  PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV-LT 357
               VN + G     +      P P + WS +G    + P    ++   T   DG  + LT
Sbjct: 2436 LRDVNADEGQELVLSAPFISNPMPEVIWSKDG--VTLTPN---ERLLMTC--DGKHIGLT 2488

Query: 358  INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
            I   +  DS N   C   N  G         V       PP+ T   S+Q     + A  
Sbjct: 2489 IKPAEAADSGN-YTCLLANPLGEDSSACNANVRKV--YKPPVFTQKISDQQQVFGNNAKI 2545

Query: 418  PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHG 474
            P T    P P + WYF+ + + ++ + ++ NDG    L++ + +K D G Y C+AS+R G
Sbjct: 2546 PVTVSGVPYPDLEWYFQDKPIPKSEKYSIKNDGDHHMLIVNNCEKGDQGVYKCIASNREG 2605

Query: 475  KYVWSGAL 482
            K +  G L
Sbjct: 2606 KDITQGRL 2613



 Score = 97.1 bits (231), Expect = 3e-18
 Identities = 106/422 (25%), Positives = 169/422 (40%), Gaps = 37/422 (8%)

Query: 4    DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-THRSILP 62
            + V     P  + +  D +     P  ++ +  G+P P ++W+  G  +  D +H +I+ 
Sbjct: 2318 EIVPKESKPVFVAELQDASSIEGFPVKMDIKVVGNPKPKLQWFHNGHEIKPDASHIAIVE 2377

Query: 63   AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE--PE----- 115
                            D+G+Y   A N  G+  S+ A L+VA   +E   E  P+     
Sbjct: 2378 NPDNSSSLIIEKTAPGDSGLYEVIAQNPEGSTASK-AKLYVAPKADETATEEAPQFVSAL 2436

Query: 116  -SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQ 172
                + +G  +VL   P   +P P V W K+G TL    +  +   DG +  L I+ A  
Sbjct: 2437 RDVNADEGQELVLSA-PFISNPMPEVIWSKDGVTLT-PNERLLMTCDGKHIGLTIKPAEA 2494

Query: 173  TDAGRYQCIARNAAGTRESAI-ATLKIHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPL 230
             D+G Y C+  N  G   SA  A ++   KP + T    D     G++      V G P 
Sbjct: 2495 ADSGNYTCLLANPLGEDSSACNANVRKVYKPPVFTQKISDQQQVFGNNAKIPVTVSGVPY 2554

Query: 231  PDVLWRRSAGGGNMPLG-RVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGY 286
            PD+ W        +P   +  + +DG    L ++N    D+G Y C A N  G     G 
Sbjct: 2555 PDLEWYFQ--DKPIPKSEKYSIKNDGDHHMLIVNNCEKGDQGVYKCIASNREGKDITQGR 2612

Query: 287  LTVY---------DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337
            L +          +PP         ++  G VA+FT  ATG PEP + W     +  +FP
Sbjct: 2613 LDIVNEIKKHSRSEPPVFLKKIGDCDIYEGMVAKFTACATGYPEPEVEWFKNDQK--LFP 2670

Query: 338  GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397
                D++      +G+  LTI +  + D      C   N  G      +L   S D +  
Sbjct: 2671 S---DRFLIDIEPNGLLRLTIKNVTEYDV-GRYSCRIFNPYGDDICHAELFYDSLDSQQK 2726

Query: 398  PI 399
            P+
Sbjct: 2727 PL 2728



 Score = 96.7 bits (230), Expect = 3e-18
 Identities = 123/474 (25%), Positives = 190/474 (40%), Gaps = 52/474 (10%)

Query: 37   GSPSPAIRWYKGG--VLVVSDTHRSILPAGGLFFLRATHGRVH-SDAGVYWCEATNSYGT 93
            G P P +++YK    +L  +D  + I     L F       V  +DAG Y C+ATN +G 
Sbjct: 1059 GDPKPRVKFYKDEKEILETNDRIQIIRDKDYLGFYELVIADVQKTDAGTYSCKATNKHGE 1118

Query: 94   ARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDG 153
            A        +A   E+    P    S Q        + P G  +P   WK+NG+   FD 
Sbjct: 1119 ANCEA----IATTVED--KNPFGALSGQ--------ILPAGE-KPVFQWKRNGEE--FDP 1161

Query: 154  DSRMHLVDGGN-----LVIQDARQTDAGRYQCIARNAAG--------TRESAIATLKIHI 200
            + R  ++ G +     LV Q  +  DAG Y C+A+ + G        + + AI TL    
Sbjct: 1162 EERFKVLFGEDEDSLALVFQHVKPEDAGIYTCVAQTSTGNISCSAELSVQGAIQTLNREP 1221

Query: 201  -KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---S 256
             KP L+    +  A  G S   + +  G P P V W+       +      + +D    S
Sbjct: 1222 EKPTLVIEHREANASIGGSAILELQCKGFPKPAVQWKHDGEVIQVDDRHKFMYEDEESMS 1281

Query: 257  LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316
            L + NV   D G Y+ EA N +G   +S  L V  PP I      +   +G   +     
Sbjct: 1282 LVIKNVDTVDAGVYTIEAINELGQDESSINLVVKAPPKIK-KITDITCSAGETIKMEIEV 1340

Query: 317  TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV--TVLTINDTDKNDSRNTIVCSA 374
             G P+PT+   V  N   +    S  K  ++++   +   V+ + +   + + N  +  A
Sbjct: 1341 EGFPQPTV--QVTNNGKDV-TAESNVKISSSSIGKSLEKVVVEVKEIKLSQAGNYSI-KA 1396

Query: 375  VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF- 433
             N    +      TV S     P I+ N  S      K            PE  + WY  
Sbjct: 1397 TNDLSQTSEYWSCTVKS----KPVIVKNFESEYIHGEKENVQMTVRIDAYPEAKLTWYHD 1452

Query: 434  EGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
            E E  I + +  V++DG   TL +    + D+G YT  A++ HG    S  LL+
Sbjct: 1453 ETEIKITDSKYTVSSDGNAYTLKITGATRVDAGKYTVKATNEHGSATSSTQLLI 1506



 Score = 83.4 bits (197), Expect = 3e-14
 Identities = 118/549 (21%), Positives = 213/549 (38%), Gaps = 67/549 (12%)

Query: 31   LNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
            +  R    P   + WY     + ++D+  ++   G  + L+ T G    DAG Y  +ATN
Sbjct: 1435 MTVRIDAYPEAKLTWYHDETEIKITDSKYTVSSDGNAYTLKIT-GATRVDAGKYTVKATN 1493

Query: 90   SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
             +G+A S  +T  +     EF  + ++   A+GD+ V   +     P P+  W  +G  +
Sbjct: 1494 EHGSATS--STQLLIKCAPEFTHKLKNITVAEGDSNVELVVGVDAYPRPHAKWYIDGIEI 1551

Query: 150  LFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG 207
                +   H+ +G +  L++        G Y C   N  G  E     + ++ KP +  G
Sbjct: 1552 DEKRNDFRHVEEGNDFKLIMNQVATNMQGNYTCKIMNDYGKLEDN-CVVTVNCKPKVKRG 1610

Query: 208  PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA-- 265
             ++V  Q G S T +  V  +P   + W +  G       R+K+  D + R++N  L   
Sbjct: 1611 LKNVEVQEGKSFTLEVEVYSEPEAKIKWFKD-GHEIYEDARIKISRD-TQRIENYYLTLN 1668

Query: 266  -----DEGEYSCEAENSVGAVSASGYLTVYDPPSINLS-------------------PNS 301
                 D G Y  +A N +G  +++  + V    +++L                    P  
Sbjct: 1669 LARTEDAGTYEMKATNFIGETTSTCKVAVLTSEALSLEQTVTKTLIATTEEPEEGAVPEI 1728

Query: 302  VNVE-------SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
            V+V+            ++   ATG P+P   W  +G        ++ DK+ A  V     
Sbjct: 1729 VHVDVFQQHSYESVPLKYEVIATGIPKPEAIWYHDGK------PITPDKHTAITVDGDHY 1782

Query: 355  VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK-- 412
             L +   D  D+    V    N  G    +G+L+++   +   PI+T GP  + + +   
Sbjct: 1783 KLEVQSLDLVDAGEYKVV-VQNKVGEKSHQGELSLSGIAEYRKPILTQGPGLKDIKVNKG 1841

Query: 413  SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG------------TLVLKDLDKS 460
                 P      P P I    +G+ +++ +   +  D             TL + + +  
Sbjct: 1842 DKVCEPVVFTADPAPEIVLLKDGQPVVETNNVKLKVDKKDAENGLVQYTCTLNILEAEIK 1901

Query: 461  DSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSV 520
            DSG Y     +++G+ V SG   +D    P I      D   LPG           +   
Sbjct: 1902 DSGRYELKVKNKYGELVTSG--WIDVLAKPEISGLN--DTKCLPGDTICFEALVQANPKP 1957

Query: 521  TLSWSQNNK 529
             +SW++ N+
Sbjct: 1958 KVSWTRGNE 1966



 Score = 79.8 bits (188), Expect = 4e-13
 Identities = 106/422 (25%), Positives = 168/422 (39%), Gaps = 41/422 (9%)

Query: 79   DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPE---------SKQSAQGDTVVLEC 129
            DAG+Y C A  S G   S +A L V    +    EPE            ++ G + +LE 
Sbjct: 1187 DAGIYTCVAQTSTGNI-SCSAELSVQGAIQTLNREPEKPTLVIEHREANASIGGSAILE- 1244

Query: 130  LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD--GGNLVIQDARQTDAGRYQCIARNAAG 187
            L  +G P+P V WK +G+ +  D   +    D    +LVI++    DAG Y   A N  G
Sbjct: 1245 LQCKGFPKPAVQWKHDGEVIQVDDRHKFMYEDEESMSLVIKNVDTVDAGVYTIEAINELG 1304

Query: 188  TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGGGN 243
              ES+I  L +   P  I    D+    G ++  +  V G P P V    +        N
Sbjct: 1305 QDESSI-NLVVKAPP-KIKKITDITCSAGETIKMEIEVEGFPQPTVQVTNNGKDVTAESN 1362

Query: 244  MPLGRV---KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLS 298
            + +      K L+   + +  + L+  G YS +A N +   S     TV   P I  N  
Sbjct: 1363 VKISSSSIGKSLEKVVVEVKEIKLSQAGNYSIKATNDLSQTSEYWSCTVKSKPVIVKNFE 1422

Query: 299  PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
               ++ E  NV + T      PE  + W  +     I    +  KY  ++  +  T+   
Sbjct: 1423 SEYIHGEKENV-QMTVRIDAYPEAKLTWYHDETEIKI----TDSKYTVSSDGNAYTLKIT 1477

Query: 359  NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
              T  +  + T+   A N  GS+    +L +     +  P  T+   N T+      V  
Sbjct: 1478 GATRVDAGKYTV--KATNEHGSATSSTQLLI-----KCAPEFTHKLKNITVAEGDSNVEL 1530

Query: 419  CTAI-CTPEPIIAWYFEGEALIQ--NHRRNVT--NDGTLVLKDLDKSDSGTYTCVASSRH 473
               +   P P   WY +G  + +  N  R+V   ND  L++  +  +  G YTC   + +
Sbjct: 1531 VVGVDAYPRPHAKWYIDGIEIDEKRNDFRHVEEGNDFKLIMNQVATNMQGNYTCKIMNDY 1590

Query: 474  GK 475
            GK
Sbjct: 1591 GK 1592



 Score = 73.7 bits (173), Expect = 3e-11
 Identities = 112/476 (23%), Positives = 187/476 (39%), Gaps = 43/476 (9%)

Query: 35   AGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTA 94
            A G P P   WY  G  +  D H +I   G  + L      +  DAG Y     N  G  
Sbjct: 1750 ATGIPKPEAIWYHDGKPITPDKHTAITVDGDHYKLEVQSLDL-VDAGEYKVVVQNKVGE- 1807

Query: 95   RSRNATLH---VAVLREEFRLE-PESKQSA--QGDTVVLECLPPRGSPEPNVYWKKNGQT 148
            +S    L    +A  R+    + P  K     +GD V  E +     P P +   K+GQ 
Sbjct: 1808 KSHQGELSLSGIAEYRKPILTQGPGLKDIKVNKGDKVC-EPVVFTADPAPEIVLLKDGQP 1866

Query: 149  LLFDGDSRMHL--VDGGNLVIQ--------DARQTDAGRYQCIARNAAGTRESAIATLKI 198
            ++   + ++ +   D  N ++Q        +A   D+GRY+   +N  G   ++   + +
Sbjct: 1867 VVETNNVKLKVDKKDAENGLVQYTCTLNILEAEIKDSGRYELKVKNKYGELVTS-GWIDV 1925

Query: 199  HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGGGNMPLGRVKVLDD 254
              KP  I+G  D     G ++ F+  V  +P P V W R         N  +      D 
Sbjct: 1926 LAKPE-ISGLNDTKCLPGDTICFEALVQANPKPKVSWTRGNENLCNHENCEVIADVDADK 1984

Query: 255  GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV-YDPPSINLSPNSVNVESGNVARFT 313
              L   +V   ++G+Y+  A NS G  +    L V  + P+  + P S ++         
Sbjct: 1985 YRLVFQSVSPCEDGKYTITATNSEGRAAVDFNLAVLVEKPTFIVQPESQSIHDYRPVSTK 2044

Query: 314  CTATGRPEPTMFWSVEGNRTIIFPGMS---RDKYHATA-VFDGV----TVLTINDTDKND 365
                G P PT+ W  + ++ I +  ++   +DK +A      G     +VL I    +ND
Sbjct: 2045 VLVHGVPLPTIEW-FKDDKPINYEAINKPGKDKLYAKEDTKKGTDQIESVLDIKSFREND 2103

Query: 366  SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
                  C A N  G +    KL + S     P  +    +   +      V  C    +P
Sbjct: 2104 V-GAYTCVATNEIGVTKAPFKLAMLS---LAPSFVKKLDNALDVLQGEPLVLECCVDGSP 2159

Query: 426  EPIIAWYFEGEALIQNHRRNV-TNDGTLVLKDLDK---SDSGTYTCVASSRHGKYV 477
             P + W  +G+ +  +    + TN   LV  +++    +DSG Y  + S+ HG+ V
Sbjct: 2160 LPTVQWLKDGDEVKPSESIKISTNPDGLVKLEINSCQPNDSGAYKLIISNPHGEKV 2215



 Score = 73.7 bits (173), Expect = 3e-11
 Identities = 101/477 (21%), Positives = 178/477 (37%), Gaps = 43/477 (9%)

Query: 38   SPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS-DAGVYWCEATNSYGTARS 96
            +P P + W +G   + +  +  ++        R     V   + G Y   ATNS G A +
Sbjct: 1954 NPKPKVSWTRGNENLCNHENCEVIADVDADKYRLVFQSVSPCEDGKYTITATNSEGRA-A 2012

Query: 97   RNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFD---- 152
             +  L V V +  F ++PES QS      V   +   G P P + W K+ + + ++    
Sbjct: 2013 VDFNLAVLVEKPTFIVQPES-QSIHDYRPVSTKVLVHGVPLPTIEWFKDDKPINYEAINK 2071

Query: 153  -GDSRMHLVDGGN---------LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKP 202
             G  +++  +            L I+  R+ D G Y C+A N  G  ++      + + P
Sbjct: 2072 PGKDKLYAKEDTKKGTDQIESVLDIKSFRENDVGAYTCVATNEIGVTKAPFKLAMLSLAP 2131

Query: 203  YLITGPEDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL--DDG--SL 257
              +   ++ +    G  +  +C V G PLP V W +  G    P   +K+    DG   L
Sbjct: 2132 SFVKKLDNALDVLQGEPLVLECCVDGSPLPTVQWLKD-GDEVKPSESIKISTNPDGLVKL 2190

Query: 258  RLDNVILADEGEYSCEAENSVG---AVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
             +++    D G Y     N  G   A+ A         P       S  V  G   +   
Sbjct: 2191 EINSCQPNDSGAYKLIISNPHGEKVALCAVAVKPEEMQPKFLKPITSQTVVVGEPLKLEA 2250

Query: 315  TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
              TG P P + W  +G   ++ P    +  ++    +G   L I+     D+     C  
Sbjct: 2251 QVTGFPAPEVKWYKDG--MLLRPSPEINFINSP---NGQIGLIIDAAQPLDA-GVYKCLI 2304

Query: 375  VNYAGSSFVRGKLTVTSDDDRPPPI--ITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
             N  G      K+ +   + +P  +  + +  S +  P+K         +  P+P + W+
Sbjct: 2305 ANKGGEIEGVSKVEIVPKESKPVFVAELQDASSIEGFPVK----MDIKVVGNPKPKLQWF 2360

Query: 433  FEGEALIQNHR-----RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
              G  +  +        N  N  +L+++     DSG Y  +A +  G       L V
Sbjct: 2361 HNGHEIKPDASHIAIVENPDNSSSLIIEKTAPGDSGLYEVIAQNPEGSTASKAKLYV 2417



 Score = 68.5 bits (160), Expect = 1e-09
 Identities = 97/484 (20%), Positives = 180/484 (37%), Gaps = 35/484 (7%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPAGGLFF 68
            E P ++ +  +   +    A L  +  G P PA++W + G V+ V D H+ +        
Sbjct: 1222 EKPTLVIEHREANASIGGSAILELQCKGFPKPAVQWKHDGEVIQVDDRHKFMYEDEESMS 1281

Query: 69   LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
            L   +     DAGVY  EA N  G   S   ++++ V       +      + G+T+ +E
Sbjct: 1282 LVIKNVDT-VDAGVYTIEAINELGQDES---SINLVVKAPPKIKKITDITCSAGETIKME 1337

Query: 129  CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN------LVIQDARQTDAGRYQCIA 182
             +   G P+P V    NG+ +  + + ++     G       + +++ + + AG Y   A
Sbjct: 1338 -IEVEGFPQPTVQVTNNGKDVTAESNVKISSSSIGKSLEKVVVEVKEIKLSQAGNYSIKA 1396

Query: 183  RNAAGTRESAIATLKIHIKPYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
             N   ++ S   +  +  KP ++   E + +     +V    R+   P   + W      
Sbjct: 1397 TNDL-SQTSEYWSCTVKSKPVIVKNFESEYIHGEKENVQMTVRIDAYPEAKLTWYHDETE 1455

Query: 242  GNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
              +   +  V  DG   +L++      D G+Y+ +A N  G+ ++S  L +   P     
Sbjct: 1456 IKITDSKYTVSSDGNAYTLKITGATRVDAGKYTVKATNEHGSATSSTQLLIKCAPEFTHK 1515

Query: 299  PNSVNVESGNV-ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
              ++ V  G+            P P   W ++G   I       D  H   V +G     
Sbjct: 1516 LKNITVAEGDSNVELVVGVDAYPRPHAKWYIDG---IEIDEKRNDFRH---VEEGNDFKL 1569

Query: 358  INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
            I +    + +    C  +N  G       +TV        P +  G  N  +        
Sbjct: 1570 IMNQVATNMQGNYTCKIMNDYGKLEDNCVVTVNC-----KPKVKRGLKNVEVQEGKSFTL 1624

Query: 418  PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT------LVLKDLDKSDSGTYTCVASS 471
                   PE  I W+ +G  + ++ R  ++ D        L L      D+GTY   A++
Sbjct: 1625 EVEVYSEPEAKIKWFKDGHEIYEDARIKISRDTQRIENYYLTLNLARTEDAGTYEMKATN 1684

Query: 472  RHGK 475
              G+
Sbjct: 1685 FIGE 1688



 Score = 51.6 bits (118), Expect = 1e-04
 Identities = 54/220 (24%), Positives = 87/220 (39%), Gaps = 32/220 (14%)

Query: 397  PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT--NDGTLVL 454
            PP     P    +     +   C A+  P+P + W+     L ++ R  ++   DG  +L
Sbjct: 3564 PPFFREKPQTIAITENQPSHIHCFAVGDPKPCVQWFKNDMVLTESKRIKISVDEDGRSIL 3623

Query: 455  K--DLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPIT 512
            +       D G Y  VA ++ G+ V    ++V                ++LP  P  P  
Sbjct: 3624 RFEPALHFDVGVYKVVARNKVGQTVARCRIVV----------------ATLPDAPDSPEI 3667

Query: 513  HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHY 572
               + T + L W Q    G S++L Y ++      LS      N   W  +A  +    Y
Sbjct: 3668 SANSGTEILLRWKQPRDDGHSTVLCYSLQY----KLS------NCDAWTTVADNIDHEFY 3717

Query: 573  VVKSLIPGITYMFIVRTENSHGLSGPS-PVSDSVTVGDDS 611
            ++  L P   Y F + ++N  G S    PVS S TVG D+
Sbjct: 3718 LLHDLQPNTNYQFRLASKNRIGWSEMGIPVSAS-TVGGDA 3756



 Score = 51.2 bits (117), Expect = 2e-04
 Identities = 90/403 (22%), Positives = 159/403 (39%), Gaps = 51/403 (12%)

Query: 165  LVIQDARQTDAGRYQCIARNAAGTR----ESAIATL------KIHIKPYLITGPEDVVAQ 214
            L I++  +TDAG Y   A++A+ T     + A+         K + +P  +   +D    
Sbjct: 987  LDIKNCSETDAGTYTIRAQSASETTTVSAQLAVGQAPGHDETKTNTEPAFLVSLKDAEMI 1046

Query: 215  TGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS------LRLDNVILADEG 268
              +   F  ++ GDP P V + +          R++++ D        L + +V   D G
Sbjct: 1047 ENTLFRFMVKIIGDPKPRVKFYKDEKEILETNDRIQIIRDKDYLGFYELVIADVQKTDAG 1106

Query: 269  EYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328
             YSC+A N  G  +     T  +  +   + +   + +G    F     G       +  
Sbjct: 1107 TYSCKATNKHGEANCEAIATTVEDKNPFGALSGQILPAGEKPVFQWKRNGEE-----FDP 1161

Query: 329  EGNRTIIFPGMSRDKYHATAVFDGVTV--LTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
            E    ++F     D+     VF  V      I       S   I CSA        V+G 
Sbjct: 1162 EERFKVLF---GEDEDSLALVFQHVKPEDAGIYTCVAQTSTGNISCSA-----ELSVQGA 1213

Query: 387  L-TVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN 445
            + T+  + ++P  +I +  +N ++   ++    C     P+P + W  +GE +  + R  
Sbjct: 1214 IQTLNREPEKPTLVIEHREANASIGGSAILELQCKGF--PKPAVQWKHDGEVIQVDDRHK 1271

Query: 446  VTNDG----TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVS 501
               +     +LV+K++D  D+G YT  A +  G+   S  L+V +P  P I   +  D++
Sbjct: 1272 FMYEDEESMSLVIKNVDTVDAGVYTIEAINELGQDESSINLVVKAP--PKIK--KITDIT 1327

Query: 502  SLPGPPTK---------PITHNVTDTSVTLSWSQNNKIGSSSI 535
               G   K           T  VT+    ++   N KI SSSI
Sbjct: 1328 CSAGETIKMEIEVEGFPQPTVQVTNNGKDVTAESNVKISSSSI 1370



 Score = 50.8 bits (116), Expect = 2e-04
 Identities = 37/121 (30%), Positives = 57/121 (47%), Gaps = 8/121 (6%)

Query: 9    GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLF 67
            G  P+  E+P  + +  +QP+ ++C A G P P ++W+K   VL  S   +  +   G  
Sbjct: 3562 GYPPFFREKPQTIAITENQPSHIHCFAVGDPKPCVQWFKNDMVLTESKRIKISVDEDGRS 3621

Query: 68   FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ-SAQGDTVV 126
             LR     +H D GVY   A N  G   +R   + VA L +     P+S + SA   T +
Sbjct: 3622 ILR-FEPALHFDVGVYKVVARNKVGQTVAR-CRIVVATLPD----APDSPEISANSGTEI 3675

Query: 127  L 127
            L
Sbjct: 3676 L 3676



 Score = 48.8 bits (111), Expect = 9e-04
 Identities = 116/527 (22%), Positives = 188/527 (35%), Gaps = 61/527 (11%)

Query: 11   APYIIEQPLDVTVARHQP-ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            AP    +  ++TVA       L       P P  +WY  G+ +    +       G  F 
Sbjct: 1509 APEFTHKLKNITVAEGDSNVELVVGVDAYPRPHAKWYIDGIEIDEKRNDFRHVEEGNDFK 1568

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
               +    +  G Y C+  N YG     N  + V   + + +   ++ +  +G +  LE 
Sbjct: 1569 LIMNQVATNMQGNYTCKIMNDYGKLED-NCVVTVNC-KPKVKRGLKNVEVQEGKSFTLE- 1625

Query: 130  LPPRGSPEPNVYWKKNGQTLLFDGDSRM----HLVDGGNLVIQDARQTDAGRYQCIARNA 185
            +     PE  + W K+G  +  D   ++      ++   L +  AR  DAG Y+  A N 
Sbjct: 1626 VEVYSEPEAKIKWFKDGHEIYEDARIKISRDTQRIENYYLTLNLARTEDAGTYEMKATNF 1685

Query: 186  AGTRES----AIAT-----LKIHIKPYLITGPE-------------DVVAQTG-SSVTFQ 222
             G   S    A+ T     L+  +   LI   E             DV  Q    SV  +
Sbjct: 1686 IGETTSTCKVAVLTSEALSLEQTVTKTLIATTEEPEEGAVPEIVHVDVFQQHSYESVPLK 1745

Query: 223  CRV--GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENS 277
              V   G P P+ +W    G    P     +  DG    L + ++ L D GEY    +N 
Sbjct: 1746 YEVIATGIPKPEAIWYHD-GKPITPDKHTAITVDGDHYKLEVQSLDLVDAGEYKVVVQNK 1804

Query: 278  VGAVSASGYLTV-----YDPPSINLSP--NSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
            VG  S  G L++     Y  P +   P    + V  G+        T  P P +    +G
Sbjct: 1805 VGEKSHQGELSLSGIAEYRKPILTQGPGLKDIKVNKGDKVCEPVVFTADPAPEIVLLKDG 1864

Query: 331  NRTIIFPG--MSRDKYHA-TAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387
               +      +  DK  A   +      L I + +  DS         N  G     G +
Sbjct: 1865 QPVVETNNVKLKVDKKDAENGLVQYTCTLNILEAEIKDS-GRYELKVKNKYGELVTSGWI 1923

Query: 388  TVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT 447
             V +      P I+     + LP  ++  F       P+P ++W    E L  +    V 
Sbjct: 1924 DVLA-----KPEISGLNDTKCLPGDTIC-FEALVQANPKPKVSWTRGNENLCNHENCEVI 1977

Query: 448  ND-----GTLVLKDLDKSDSGTYTCVASSRHGKYV--WSGALLVDSP 487
             D       LV + +   + G YT  A++  G+    ++ A+LV+ P
Sbjct: 1978 ADVDADKYRLVFQSVSPCEDGKYTITATNSEGRAAVDFNLAVLVEKP 2024



 Score = 41.9 bits (94), Expect = 0.10
 Identities = 32/124 (25%), Positives = 53/124 (42%), Gaps = 6/124 (4%)

Query: 165  LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR 224
            L I      D G Y+ +A N  G     +  L+I   P  +  P++       +   + +
Sbjct: 2942 LFINKMLDRDVGWYEAVATNEHGEARQRVR-LEIAEHPRFLKRPDETFIMARKNGRIEAK 3000

Query: 225  VGGDPLPDVLWRRSAGGGNMPLGRVKVL----DDGSLRLDNVILADEGEYSCEAENSVGA 280
            + G PLP+V W +      +   R+K+     D   L + + I+ D G YS  A N  G+
Sbjct: 3001 LVGIPLPEVHWFKD-WKPIVDSSRIKISSYDPDIYVLSIHDSIIKDGGLYSISARNIAGS 3059

Query: 281  VSAS 284
            +S S
Sbjct: 3060 ISTS 3063



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 20/101 (19%), Positives = 44/101 (43%), Gaps = 1/101 (0%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            E P  +++P +  +   +   +  +  G P P + W+K    +V  +   I       ++
Sbjct: 2976 EHPRFLKRPDETFIMARKNGRIEAKLVGIPLPEVHWFKDWKPIVDSSRIKISSYDPDIYV 3035

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEF 110
             + H  +  D G+Y   A N  G+  S + T+H+    +++
Sbjct: 3036 LSIHDSIIKDGGLYSISARNIAGSI-STSVTVHIEENEDQY 3075



 Score = 36.7 bits (81), Expect = 3.9
 Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 8/125 (6%)

Query: 79   DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
            D G Y   ATN +G AR R   L +A      +   E+   A+ +  +   L   G P P
Sbjct: 2951 DVGWYEAVATNEHGEARQR-VRLEIAEHPRFLKRPDETFIMARKNGRIEAKLV--GIPLP 3007

Query: 139  NVYWKKNGQTLLFDGDSRMHLVDGGNLV--IQDARQTDAGRYQCIARNAAGTRESAIATL 196
             V+W K+ + ++     ++   D    V  I D+   D G Y   ARN AG+  +++   
Sbjct: 3008 EVHWFKDWKPIVDSSRIKISSYDPDIYVLSIHDSIIKDGGLYSISARNIAGSISTSVT-- 3065

Query: 197  KIHIK 201
             +HI+
Sbjct: 3066 -VHIE 3069


>UniRef50_Q8WZ75 Cluster: Roundabout homolog 4 precursor; n=22;
           Theria|Rep: Roundabout homolog 4 precursor - Homo
           sapiens (Human)
          Length = 1007

 Score =  147 bits (355), Expect = 2e-33
 Identities = 86/212 (40%), Positives = 115/212 (54%), Gaps = 14/212 (6%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSDTHRSILPAGGLFF 68
           P I+  P D       PA ++C+A G P P IRW   G    +V  D H  +LP G L  
Sbjct: 32  PQILVHPQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPPDPHH-LLPDGTLLL 90

Query: 69  LRA-THGRVH------SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
           L+    G  H      +D GVY CEA+N  GTA SR A L VAVLRE+F+++P    +  
Sbjct: 91  LQPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARLSVAVLREDFQIQPRDMVAVV 150

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
           G+   LEC PP G PEP V W K+G+ L        H V GG+L++  A ++D G Y C+
Sbjct: 151 GEQFTLECGPPWGHPEPTVSWWKDGKPLAL--QPGRHTVSGGSLLMARAEKSDEGTYMCV 208

Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVA 213
           A N+AG RES  A + I  +P   T P +++A
Sbjct: 209 ATNSAGHRESRAARVSIQ-EPQDYTEPVELLA 239



 Score = 60.9 bits (141), Expect = 2e-07
 Identities = 50/196 (25%), Positives = 84/196 (42%), Gaps = 25/196 (12%)

Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
           PP I + P     +    AR +C A+G+P PT+ W + G    + P    D +H     D
Sbjct: 31  PPQILVHPQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPP---DPHHLLP--D 85

Query: 352 GVTVLTINDTDKNDSRN---------TIVCSAVNYAGSSFVRG---KLTVTSDDDRPPPI 399
           G T+L +    +  + +            C A N  G++  RG    + V  +D +  P 
Sbjct: 86  G-TLLLLQPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARLSVAVLREDFQIQP- 143

Query: 400 ITNGPSNQTLPIKSMAVFPCTAICT-PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLD 458
                 +    +       C      PEP ++W+ +G+ L     R+  + G+L++   +
Sbjct: 144 -----RDMVAVVGEQFTLECGPPWGHPEPTVSWWKDGKPLALQPGRHTVSGGSLLMARAE 198

Query: 459 KSDSGTYTCVASSRHG 474
           KSD GTY CVA++  G
Sbjct: 199 KSDEGTYMCVATNSAG 214



 Score = 54.0 bits (124), Expect = 2e-05
 Identities = 46/134 (34%), Positives = 61/134 (45%), Gaps = 8/134 (5%)

Query: 693 EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKW 752
           E+  L     YEF + P   +  G  SN  + +  + VP  PP  + +   N T V + W
Sbjct: 309 ELGGLHWGQDYEFKVRPSSGRARGPDSNVLLLRLPEKVPSAPPQEVTLKPGNGT-VFVSW 367

Query: 753 SPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN-TTVHQATSLIMTNLTSGVSYSVQIA 811
            PP  +  NGII GY V   W     N S+   N T V + T L +     G SY VQ+A
Sbjct: 368 VPPPAENHNGIIRGYQV---W--SLGNTSLPPANWTVVGEQTQLEIATHMPG-SYCVQVA 421

Query: 812 AETIIGLGPFSQKV 825
           A T  G G  S+ V
Sbjct: 422 AVTGAGAGEPSRPV 435



 Score = 51.2 bits (117), Expect = 2e-04
 Identities = 55/214 (25%), Positives = 85/214 (39%), Gaps = 26/214 (12%)

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM-PLGRVKVLDDGSLRL- 259
           P ++  P+D + Q        C+  G P P + W  +    +M P     +L DG+L L 
Sbjct: 32  PQILVHPQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPPDPHHLLPDGTLLLL 91

Query: 260 ----------DNVILADEGEYSCEAENSVG-AVSASGYLTV-YDPPSINLSPNSVNVESG 307
                        +  D G Y+CEA N +G AVS    L+V        + P  +    G
Sbjct: 92  QPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARLSVAVLREDFQIQPRDMVAVVG 151

Query: 308 NVARFTC-TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
                 C    G PEPT+ W  +G    + PG      H  +   G ++L     +K+D 
Sbjct: 152 EQFTLECGPPWGHPEPTVSWWKDGKPLALQPGR-----HTVS---GGSLLMAR-AEKSD- 201

Query: 367 RNTIVCSAVNYAGSSFVR-GKLTVTSDDDRPPPI 399
             T +C A N AG    R  ++++    D   P+
Sbjct: 202 EGTYMCVATNSAGHRESRAARVSIQEPQDYTEPV 235



 Score = 39.5 bits (88), Expect = 0.55
 Identities = 33/103 (32%), Positives = 43/103 (41%), Gaps = 14/103 (13%)

Query: 394 DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL--IQNHRRNVTNDGT 451
           D PP I+ + P +Q       A   C A   P P I W   G+ L  +     ++  DGT
Sbjct: 29  DSPPQILVH-PQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPPDPHHLLPDGT 87

Query: 452 LVLKDLD-----------KSDSGTYTCVASSRHGKYVWSGALL 483
           L+L                +D G YTC AS+R G  V  GA L
Sbjct: 88  LLLLQPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARL 130


>UniRef50_Q9NR99 Cluster: Matrix-remodeling-associated protein 5
            precursor; n=12; Amniota|Rep:
            Matrix-remodeling-associated protein 5 precursor - Homo
            sapiens (Human)
          Length = 2828

 Score =  147 bits (355), Expect = 2e-33
 Identities = 136/499 (27%), Positives = 208/499 (41%), Gaps = 48/499 (9%)

Query: 9    GEAPYII-EQPLDVTVARHQPATLNCRAGGSPSPAIRWYK--GGVLVVSDTH--RSILPA 63
            GE P I+ + P  V+V         C A G P P + W K   G L+  +T   R  +  
Sbjct: 1850 GEKPQILTKSPQTVSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVLK 1909

Query: 64   GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-G 122
             G   +R    +   D G Y C A+N +G  R     L V V + +         +   G
Sbjct: 1910 NGTLVIRKVQVQ---DRGQYMCTASNLHGLDRMV-VLLSVTVQQPQILASHYQDVTVYLG 1965

Query: 123  DTVVLECLPPRGSPEPNVYW----KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY 178
            DT+ +ECL  +G+P P + W    ++  QT+    +SR+ L +   L I++A  +D G Y
Sbjct: 1966 DTIAMECLA-KGTPAPQISWIFPDRRVWQTVS-PVESRITLHENRTLSIKEASFSDRGVY 2023

Query: 179  QCIARNAAGTRESAIATLKIHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
            +C+A NAAG    AI      + P +     E++    G S+   C     PLP V W  
Sbjct: 2024 KCVASNAAGADSLAIRLHVAALPPVIHQEKLENISLPPGLSIHIHCTAKAAPLPSVRWVL 2083

Query: 238  SAGGGNMPL----GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
              G    P     G + V  +G+L + N+   D G Y C A N VG+   +  L V    
Sbjct: 2084 GDGTQIRPSQFLHGNLFVFPNGTLYIRNLAPKDSGRYECVAANLVGSARRTVQLNVQRAA 2143

Query: 294  S----INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI--IFPGMSRDKYHAT 347
            +       SP   +V  G   +  C+A+G P P + W +   R I  +F   SR K  A 
Sbjct: 2144 ANARITGTSPRRTDVRYGGTLKLDCSASGDPWPRILWRLPSKRMIDALFSFDSRIKVFAN 2203

Query: 348  AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407
                 + V ++ D D  D     +C A N  G  +V  K+ V     +P  I     ++ 
Sbjct: 2204 GT---LVVKSVTDKDAGD----YLCVARNKVGDDYVVLKVDVVM---KPAKIEHKEENDH 2253

Query: 408  TLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN-----------VTNDGTLVLKD 456
             +         C A   P P I+W     +L+ +  ++           V N+GTL   +
Sbjct: 2254 KVFYGGDLKVDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNE 2313

Query: 457  LDKSDSGTYTCVASSRHGK 475
            +   + G YTC A ++ GK
Sbjct: 2314 VGMREEGDYTCFAENQVGK 2332



 Score =  138 bits (334), Expect = 9e-31
 Identities = 136/480 (28%), Positives = 206/480 (42%), Gaps = 55/480 (11%)

Query: 31   LNCRAGGSPSPAIRWYKGGVLVVSDT---HRS--ILPAGGLFFLRATHGRVHSDAGVYWC 85
            ++C A  +P P++RW  G    +  +   H +  + P G L+           D+G Y C
Sbjct: 2067 IHCTAKAAPLPSVRWVLGDGTQIRPSQFLHGNLFVFPNGTLYI----RNLAPKDSGRYEC 2122

Query: 86   EATNSYGTARSRNATLHVAVLREEFRL---EPESKQSAQGDTVVLECLPPRGSPEPNVYW 142
             A N  G+AR R   L+V       R+    P       G T+ L+C    G P P + W
Sbjct: 2123 VAANLVGSAR-RTVQLNVQRAAANARITGTSPRRTDVRYGGTLKLDC-SASGDPWPRILW 2180

Query: 143  KKNGQTL---LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
            +   + +   LF  DSR+ +   G LV++     DAG Y C+ARN  G  +  +  + + 
Sbjct: 2181 RLPSKRMIDALFSFDSRIKVFANGTLVVKSVTDKDAGDYLCVARNKVGD-DYVVLKVDVV 2239

Query: 200  IKPYLITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-------GNMPLGRVK 250
            +KP  I   E  D     G  +   C   G P P++ W    G         +   GR K
Sbjct: 2240 MKPAKIEHKEENDHKVFYGGDLKVDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTK 2299

Query: 251  ---VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNVE 305
               V ++G+L  + V + +EG+Y+C AEN VG       + V   P+   N +  +V V 
Sbjct: 2300 RYVVFNNGTLYFNEVGMREEGDYTCFAENQVGKDEMRVRVKVVTAPATIRNKTYLAVQVP 2359

Query: 306  SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
             G+V    C A G P P + W    N+ I     S +KY    ++   T+L I    ++D
Sbjct: 2360 YGDVVTVACEAKGEPMPKVTWLSPTNKVI---PTSSEKYQ---IYQDGTLL-IQKAQRSD 2412

Query: 366  SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA------VFPC 419
            S N   C   N AG      + TV    +  PP I NG  N    ++ +A      +  C
Sbjct: 2413 SGN-YTCLVRNSAGED----RKTVWIHVNVQPPKI-NGNPNPITTVREIAAGGSRKLIDC 2466

Query: 420  TAICTPEPIIAWYF-EGEAL---IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
             A   P P + W F EG  L      +R  V  +G+L ++ L KSDS    C+A +  G+
Sbjct: 2467 KAEGIPTPRVLWAFPEGVVLPAPYYGNRITVHGNGSLDIRSLRKSDSVQLVCMARNEGGE 2526



 Score =  109 bits (262), Expect = 5e-22
 Identities = 127/489 (25%), Positives = 206/489 (42%), Gaps = 58/489 (11%)

Query: 31   LNCRAGGSPSPAIRW-YKGGVLVVS---------DTHRSILPAGGLFFLRATHGRVHSDA 80
            ++C A G P+P I W    G LV S          T R ++   G  +      R   D 
Sbjct: 2263 VDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNEVGMREEGD- 2321

Query: 81   GVYWCEATNSYGTARSRNATLHV---AVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
              Y C A N  G    R     V   A +R +  L   + Q   GD V + C   +G P 
Sbjct: 2322 --YTCFAENQVGKDEMRVRVKVVTAPATIRNKTYL---AVQVPYGDVVTVAC-EAKGEPM 2375

Query: 138  PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
            P V W      ++     +  +   G L+IQ A+++D+G Y C+ RN+AG     +  + 
Sbjct: 2376 PKVTWLSPTNKVIPTSSEKYQIYQDGTLLIQKAQRSDSGNYTCLVRNSAGEDRKTV-WIH 2434

Query: 198  IHIKPYLITG-PEDV-----VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL----G 247
            ++++P  I G P  +     +A  GS     C+  G P P VLW     G  +P      
Sbjct: 2435 VNVQPPKINGNPNPITTVREIAAGGSRKLIDCKAEGIPTPRVLW-AFPEGVVLPAPYYGN 2493

Query: 248  RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP--PSINLSPNS--VN 303
            R+ V  +GSL + ++  +D  +  C A N  G       LTV +P    I   P S  + 
Sbjct: 2494 RITVHGNGSLDIRSLRKSDSVQLVCMARNEGGEARLILQLTVLEPMEKPIFHDPISEKIT 2553

Query: 304  VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
              +G+     C+A G P P++ W V  N T +  G    +++  A  DG  +L I+    
Sbjct: 2554 AMAGHTISLNCSAAGTPTPSLVW-VLPNGTDLQSGQQLQRFYHKA--DG--MLHISGLSS 2608

Query: 364  NDSRNTIVCSAVNYAGSS--FVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
             D+     C A N AG +   V  K+ +  + ++    + +  + +TL +      PCT 
Sbjct: 2609 VDA-GAYRCVARNAAGHTERLVSLKVGLKPEANKQYHNLVSIINGETLKL------PCTP 2661

Query: 422  ICTPEPIIAW------YFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
                +   +W      + EG   +   R ++ ++GTL +++    D GTY C   + +G 
Sbjct: 2662 PGAGQGRFSWTLPNGMHLEGPQTL--GRVSLLDNGTLTVREASVFDRGTYVCRMETEYGP 2719

Query: 476  YVWSGALLV 484
             V S  ++V
Sbjct: 2720 SVTSIPVIV 2728



 Score =  104 bits (249), Expect = 2e-20
 Identities = 102/387 (26%), Positives = 164/387 (42%), Gaps = 22/387 (5%)

Query: 10   EAPYIIEQPLDVTVARHQPA-----TLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPA 63
            + P I   P  +T  R   A      ++C+A G P+P + W +  GV++ +  + + +  
Sbjct: 2438 QPPKINGNPNPITTVREIAAGGSRKLIDCKAEGIPTPRVLWAFPEGVVLPAPYYGNRITV 2497

Query: 64   GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ--SAQ 121
             G   L     R  SD+    C A N  G AR       +  + +    +P S++  +  
Sbjct: 2498 HGNGSLDIRSLR-KSDSVQLVCMARNEGGEARLILQLTVLEPMEKPIFHDPISEKITAMA 2556

Query: 122  GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS--RMHLVDGGNLVIQDARQTDAGRYQ 179
            G T+ L C    G+P P++ W     T L  G    R +    G L I      DAG Y+
Sbjct: 2557 GHTISLNC-SAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKADGMLHISGLSSVDAGAYR 2615

Query: 180  CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQ-TGSSVTFQCRVGGDPLPDVLWRRS 238
            C+ARNAAG  E  ++ LK+ +KP       ++V+   G ++   C   G       W   
Sbjct: 2616 CVARNAAGHTERLVS-LKVGLKPEANKQYHNLVSIINGETLKLPCTPPGAGQGRFSWTLP 2674

Query: 239  AG---GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPS 294
             G    G   LGRV +LD+G+L +    + D G Y C  E   G +V++   + +  PP 
Sbjct: 2675 NGMHLEGPQTLGRVSLLDNGTLTVREASVFDRGTYVCRMETEYGPSVTSIPVIVIAYPPR 2734

Query: 295  INLSPNSV-NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
            I   P  V     GN  +  C A G P+  + W +  +++ +  G+ + + +        
Sbjct: 2735 ITSEPTPVIYTRPGNTVKLNCMAMGIPKADITWELP-DKSHLKAGV-QARLYGNRFLHPQ 2792

Query: 354  TVLTINDTDKNDSRNTIVCSAVNYAGS 380
              LTI    + D+     C A N  GS
Sbjct: 2793 GSLTIQHATQRDA-GFYKCMAKNILGS 2818



 Score =  103 bits (246), Expect = 4e-20
 Identities = 118/475 (24%), Positives = 184/475 (38%), Gaps = 36/475 (7%)

Query: 19   LDVTVARHQPATLNCRAGGSPSPAIRWYK--GGVLVVSDTHRSILPAGGLFFLRATHGRV 76
            L V V      T+ C A G P P + W      V+  S     I   G L   +A     
Sbjct: 2354 LAVQVPYGDVVTVACEAKGEPMPKVTWLSPTNKVIPTSSEKYQIYQDGTLLIQKAQ---- 2409

Query: 77   HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPE-----SKQSAQGDTVVLECLP 131
             SD+G Y C   NS G  R +   +HV V   +    P       + +A G   +++C  
Sbjct: 2410 RSDSGNYTCLVRNSAGEDR-KTVWIHVNVQPPKINGNPNPITTVREIAAGGSRKLIDC-K 2467

Query: 132  PRGSPEPNVYWKKNGQTLL---FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
              G P P V W      +L   + G +R+ +   G+L I+  R++D+ +  C+ARN  G 
Sbjct: 2468 AEGIPTPRVLWAFPEGVVLPAPYYG-NRITVHGNGSLDIRSLRKSDSVQLVCMARNEGGE 2526

Query: 189  RESAI-ATLKIHIKPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG---GG 242
                +  T+   ++  +   P  E + A  G +++  C   G P P ++W    G     
Sbjct: 2527 ARLILQLTVLEPMEKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQS 2586

Query: 243  NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS-PNS 301
               L R     DG L +  +   D G Y C A N+ G       L V   P  N    N 
Sbjct: 2587 GQQLQRFYHKADGMLHISGLSSVDAGAYRCVARNAAGHTERLVSLKVGLKPEANKQYHNL 2646

Query: 302  VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
            V++ +G   +  CT  G  +    W++     +  P          ++ D  T LT+ + 
Sbjct: 2647 VSIINGETLKLPCTPPGAGQGRFSWTLPNGMHLEGP----QTLGRVSLLDNGT-LTVREA 2701

Query: 362  DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR----PPPIITNGPSNQTLPIKSMAV- 416
               D R T VC      G S     + V +   R    P P+I   P N T+ +  MA+ 
Sbjct: 2702 SVFD-RGTYVCRMETEYGPSVTSIPVIVIAYPPRITSEPTPVIYTRPGN-TVKLNCMAMG 2759

Query: 417  FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
             P   I    P  +    G        R +   G+L ++   + D+G Y C+A +
Sbjct: 2760 IPKADITWELPDKSHLKAGVQARLYGNRFLHPQGSLTIQHATQRDAGFYKCMAKN 2814



 Score = 89.4 bits (212), Expect = 5e-16
 Identities = 77/282 (27%), Positives = 118/282 (41%), Gaps = 17/282 (6%)

Query: 21   VTVARHQPATLNCRAGGSPSPAIRWY-KGGVLVVS--DTHRSILPAGGLFFLRATHGRVH 77
            +T       +LNC A G+P+P++ W    G  + S     R    A G+  +    G   
Sbjct: 2552 ITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKADGMLHIS---GLSS 2608

Query: 78   SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
             DAG Y C A N+ G    R  +L V +  E  +          G+T+ L C PP G+ +
Sbjct: 2609 VDAGAYRCVARNAAGHTE-RLVSLKVGLKPEANKQYHNLVSIINGETLKLPCTPP-GAGQ 2666

Query: 138  PNVYWK-KNGQTLLFDGD-SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195
                W   NG  L       R+ L+D G L +++A   D G Y C      G   ++I  
Sbjct: 2667 GRFSWTLPNGMHLEGPQTLGRVSLLDNGTLTVREASVFDRGTYVCRMETEYGPSVTSIPV 2726

Query: 196  LKIHIKPYLITGPEDVV-AQTGSSVTFQCRVGGDPLPDVLW------RRSAGGGNMPLGR 248
            + I   P + + P  V+  + G++V   C   G P  D+ W         AG      G 
Sbjct: 2727 IVIAYPPRITSEPTPVIYTRPGNTVKLNCMAMGIPKADITWELPDKSHLKAGVQARLYGN 2786

Query: 249  VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290
              +   GSL + +    D G Y C A+N +G+ S + Y+ V+
Sbjct: 2787 RFLHPQGSLTIQHATQRDAGFYKCMAKNILGSDSKTTYIHVF 2828



 Score = 53.2 bits (122), Expect = 4e-05
 Identities = 51/208 (24%), Positives = 84/208 (40%), Gaps = 13/208 (6%)

Query: 83  YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW 142
           Y+ + + +  T  +R A     V+ E        +   +G    L C   + S  P+++W
Sbjct: 455 YYTQYSQTISTKDTRQARGRSWVMIEPSGAVQRDQTVLEGGPCQLSC-NVKASESPSIFW 513

Query: 143 K-KNGQTL---LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
              +G  L   + D DS+  ++  G L I+    +D+G YQCIA+      +  +  + +
Sbjct: 514 VLPDGSILKAPMDDPDSKFSILSSGWLRIKSMEPSDSGLYQCIAQ-VRDEMDRMVYRVLV 572

Query: 199 HIKPYLITGPEDVVA---QTGSSVTFQCRVGGDPLPDVLW---RRSAGGGNMPLGRVKVL 252
              P      +D V      G SVT  C     P   + W    R           V +L
Sbjct: 573 Q-SPSTQPAEKDTVTIGKNPGESVTLPCNALAIPEAHLSWILPNRRIINDLANTSHVYML 631

Query: 253 DDGSLRLDNVILADEGEYSCEAENSVGA 280
            +G+L +  V ++D G Y C A N  GA
Sbjct: 632 PNGTLSIPKVQVSDSGYYRCVAVNQQGA 659



 Score = 48.4 bits (110), Expect = 0.001
 Identities = 49/181 (27%), Positives = 76/181 (41%), Gaps = 23/181 (12%)

Query: 20  DVTVARHQPATLNCRAGGSPSPAIRWY--KGGVLVV----SDTHRSILPAGGLFFLRATH 73
           D TV    P  L+C    S SP+I W    G +L       D+  SIL +G L       
Sbjct: 488 DQTVLEGGPCQLSCNVKASESPSIFWVLPDGSILKAPMDDPDSKFSILSSGWL----RIK 543

Query: 74  GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-----QGDTVVLE 128
               SD+G+Y C A       R     +   VL +    +P  K +       G++V L 
Sbjct: 544 SMEPSDSGLYQCIA-----QVRDEMDRMVYRVLVQSPSTQPAEKDTVTIGKNPGESVTLP 598

Query: 129 CLPPRGSPEPNVYWKKNGQTLLFD--GDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
           C      PE ++ W    + ++ D    S ++++  G L I   + +D+G Y+C+A N  
Sbjct: 599 C-NALAIPEAHLSWILPNRRIINDLANTSHVYMLPNGTLSIPKVQVSDSGYYRCVAVNQQ 657

Query: 187 G 187
           G
Sbjct: 658 G 658



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 6/62 (9%)

Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRNVTN-----DGTLVLKDLDKSDSGTYTCVASSR 472
           PC A+  PE  ++W      +I N   N ++     +GTL +  +  SDSG Y CVA ++
Sbjct: 598 PCNALAIPEAHLSWILPNRRII-NDLANTSHVYMLPNGTLSIPKVQVSDSGYYRCVAVNQ 656

Query: 473 HG 474
            G
Sbjct: 657 QG 658


>UniRef50_Q4S6A5 Cluster: Chromosome 9 SCAF14729, whole genome
           shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 9
           SCAF14729, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 1693

 Score =  146 bits (354), Expect = 3e-33
 Identities = 139/475 (29%), Positives = 207/475 (43%), Gaps = 46/475 (9%)

Query: 4   DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
           + +  G+    + +P  + V   + ATL C A G P+P I W K     +   H+ +  +
Sbjct: 482 EVIVEGKPTASVPEP-QMVVVEGRTATLRCHAHGFPAPVITWSKLRS-PLPWRHKVVNSS 539

Query: 64  GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
                +  + GR   D+G Y C A+N  G +++    L V  L     L P++     G+
Sbjct: 540 ----LVLPSVGR--QDSGEYICRASNRMGASQA-TIKLDVETLPYATLL-PDNVAVRAGE 591

Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
            + L+CL   G+P     W +    L     SR  +V+GG+L I  A   DAG Y+C+A 
Sbjct: 592 VIRLQCLA-HGTPPLTYTWTRLDGRL----PSRA-VVNGGDLQINLAAADDAGSYKCVAS 645

Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
           N+ G+ E  IA + +     +   P+  V   GS+V F C   G     + W +  GG  
Sbjct: 646 NSVGSSE-VIAKVAVRSPLAVRVSPQVEVRAQGSAVEFTCSAAGGLDTTIEWLKE-GGAL 703

Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS--INLSPNS 301
            P   VK   DG LR++++  ++EG Y C A +S G    +  LT+   P   IN+  + 
Sbjct: 704 PPNHHVK---DGVLRIEDLEQSNEGVYICRASSSFGQAQDTARLTIQALPKVMINVRTSV 760

Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
             V  GN   F C A G PEPT+ WS  G      P       H       + +  + + 
Sbjct: 761 QTVMIGNSVEFECQALGEPEPTVQWSKVGGS---LPA------HIMVKGGMLRIEQVTEV 811

Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
           D    R    C+A N  GS   +  L V S      P I+  P  + + + S AV PC A
Sbjct: 812 DAGQYR----CTATNDVGSVQSQVVLNVQS-----LPQISALPEKKEVTVGSDAVLPCVA 862

Query: 422 ICTPEPIIAWY-FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
              P P I W   EGE       + +     L +  +   DSGTY C AS++ GK
Sbjct: 863 SGYPAPEIRWSKLEGEL----PSKCLQEVNVLTVPRVAHEDSGTYVCTASNKQGK 913



 Score =  127 bits (306), Expect = 2e-27
 Identities = 109/397 (27%), Positives = 171/397 (43%), Gaps = 34/397 (8%)

Query: 79  DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLECLPPRGSPE 137
           D+G Y C A +   +  ++   + V V  +     PE +    +G T  L C    G P 
Sbjct: 462 DSGTYVCTARSGDSSTETK---VEVIVEGKPTASVPEPQMVVVEGRTATLRC-HAHGFPA 517

Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
           P + W K    L +      H V   +LV+    + D+G Y C A N  G  ++ I  L 
Sbjct: 518 PVITWSKLRSPLPW-----RHKVVNSSLVLPSVGRQDSGEYICRASNRMGASQATIK-LD 571

Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257
           +   PY    P++V  + G  +  QC   G P     W R    G +P  R  V++ G L
Sbjct: 572 VETLPYATLLPDNVAVRAGEVIRLQCLAHGTPPLTYTWTRL--DGRLP-SRA-VVNGGDL 627

Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
           +++     D G Y C A NSVG+      + V  P ++ +SP       G+   FTC+A 
Sbjct: 628 QINLAAADDAGSYKCVASNSVGSSEVIAKVAVRSPLAVRVSPQVEVRAQGSAVEFTCSAA 687

Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
           G  + T+ W  EG       G     +H   V DGV  L I D ++++     +C A + 
Sbjct: 688 GGLDTTIEWLKEG-------GALPPNHH---VKDGV--LRIEDLEQSNE-GVYICRASSS 734

Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437
            G +    +LT+ +    P  +I    S QT+ I +   F C A+  PEP + W   G +
Sbjct: 735 FGQAQDTARLTIQA---LPKVMINVRTSVQTVMIGNSVEFECQALGEPEPTVQWSKVGGS 791

Query: 438 LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
           L       +   G L ++ + + D+G Y C A++  G
Sbjct: 792 L---PAHIMVKGGMLRIEQVTEVDAGQYRCTATNDVG 825



 Score =  120 bits (290), Expect = 2e-25
 Identities = 125/404 (30%), Positives = 169/404 (41%), Gaps = 43/404 (10%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           PY    P +V V   +   L C A G+P     W +    + S   R+++  G L    A
Sbjct: 576 PYATLLPDNVAVRAGEVIRLQCLAHGTPPLTYTWTRLDGRLPS---RAVVNGGDLQINLA 632

Query: 72  THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECL 130
                  DAG Y C A+NS G   S      VAV      R+ P+ +  AQG  V   C 
Sbjct: 633 AA----DDAGSYKCVASNSVG---SSEVIAKVAVRSPLAVRVSPQVEVRAQGSAVEFTC- 684

Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
              G  +  + W K G  L        H V  G L I+D  Q++ G Y C A ++ G  +
Sbjct: 685 SAAGGLDTTIEWLKEGGAL-----PPNHHVKDGVLRIEDLEQSNEGVYICRASSSFGQAQ 739

Query: 191 SAIATLKIHIKPYLITGPEDVV--AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
              A L I   P ++      V     G+SV F+C+  G+P P V W  S  GG++P   
Sbjct: 740 DT-ARLTIQALPKVMINVRTSVQTVMIGNSVEFECQALGEPEPTVQW--SKVGGSLP-AH 795

Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGN 308
           + V   G LR++ V   D G+Y C A N VG+V +   L V   P I+  P    V  G+
Sbjct: 796 IMV-KGGMLRIEQVTEVDAGQYRCTATNDVGSVQSQVVLNVQSLPQISALPEKKEVTVGS 854

Query: 309 VARFTCTATGRPEPTMFWS-VEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
            A   C A+G P P + WS +EG      P         +     V VLT+      DS 
Sbjct: 855 DAVLPCVASGYPAPEIRWSKLEGE----LP---------SKCLQEVNVLTVPRVAHEDS- 900

Query: 368 NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP-SNQTLP 410
            T VC+A N  G      +L V    +R  P     P S  TLP
Sbjct: 901 GTYVCTASNKQGKVEAFTRLQV---HERVMPYFAQEPLSYLTLP 941



 Score =  117 bits (282), Expect = 2e-24
 Identities = 101/314 (32%), Positives = 140/314 (44%), Gaps = 26/314 (8%)

Query: 162 GGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTF 221
           G  + I  AR  D+G Y C AR+   + E+ +  + +  KP        +V   G + T 
Sbjct: 450 GWTVTILAARPEDSGTYVCTARSGDSSTETKVEVI-VEGKPTASVPEPQMVVVEGRTATL 508

Query: 222 QCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281
           +C   G P P + W +      +P  R KV++  SL L +V   D GEY C A N +GA 
Sbjct: 509 RCHAHGFPAPVITWSKLRSP--LPW-RHKVVNS-SLVLPSVGRQDSGEYICRASNRMGAS 564

Query: 282 SASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341
            A+  L V   P   L P++V V +G V R  C A G P  T  W+    R    P    
Sbjct: 565 QATIKLDVETLPYATLLPDNVAVRAGEVIRLQCLAHGTPPLTYTWTRLDGR---LP---- 617

Query: 342 DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401
               + AV +G   L IN    +D+  +  C A N  GSS V  K+ V     R P  + 
Sbjct: 618 ----SRAVVNGGD-LQINLAAADDA-GSYKCVASNSVGSSEVIAKVAV-----RSPLAVR 666

Query: 402 NGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSD 461
             P  +     S   F C+A    +  I W  EG AL  NH      DG L ++DL++S+
Sbjct: 667 VSPQVEVRAQGSAVEFTCSAAGGLDTTIEWLKEGGALPPNHH---VKDGVLRIEDLEQSN 723

Query: 462 SGTYTCVASSRHGK 475
            G Y C ASS  G+
Sbjct: 724 EGVYICRASSSFGQ 737



 Score =  100 bits (239), Expect = 3e-19
 Identities = 77/276 (27%), Positives = 124/276 (44%), Gaps = 29/276 (10%)

Query: 78  SDAGVYWCEATNSYGTARSRNATL------HVAVLREEFRLEPESKQSAQGDTVVLECLP 131
           +D G Y C+A N++G   +R + +           + + ++ P++ Q  +GDT+ + C  
Sbjct: 25  ADEGEYTCKALNTHGEHVARVSLVVQKSGSGALGSQPQVQVSPQNIQVHEGDTLRMYCRA 84

Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
             GSP P + W KNG   L    +RM   D G L+I D + +D+G Y C+  N+ G+  +
Sbjct: 85  T-GSPTPRLSWLKNGG--LLPAQARMDRTDIGTLLIPDVQLSDSGTYMCVGSNSIGSNSA 141

Query: 192 AIATLKIHIK---PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
            +    +      P +   P     Q G S+   C   G+P P V W R++G  +     
Sbjct: 142 PVKVTVLKADQSFPAVSIQPSTADIQEGQSLELNCVAPGNPPPKVSWWRASGLSS----N 197

Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY-LTV----------YDPPSINL 297
            +VL +  LR+ +    D GEY+C  E + G  S+ G+  TV             P I +
Sbjct: 198 HQVLGN-QLRILSATAEDSGEYTCRVEGNHGNPSSGGHQATVSVSVTSSSSRLQSPIIAI 256

Query: 298 SPNSVNVESGNVARFTCTATGRPEPT-MFWSVEGNR 332
            P+S  V  G  A F C      +P  + W V  N+
Sbjct: 257 EPHSAVVRVGETATFRCRIYSGAQPVRLEWKVANNQ 292



 Score = 86.2 bits (204), Expect = 5e-15
 Identities = 70/291 (24%), Positives = 119/291 (40%), Gaps = 33/291 (11%)

Query: 159 LVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL-------KIHIKPYLITGPEDV 211
           ++ GG L        D G Y C A N  G   + ++ +        +  +P +   P+++
Sbjct: 11  VIRGGVLTFAAVDAADEGEYTCKALNTHGEHVARVSLVVQKSGSGALGSQPQVQVSPQNI 70

Query: 212 VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGSLRLDNVILADEGEY 270
               G ++   CR  G P P + W ++  GG +P   R+   D G+L + +V L+D G Y
Sbjct: 71  QVHEGDTLRMYCRATGSPTPRLSWLKN--GGLLPAQARMDRTDIGTLLIPDVQLSDSGTY 128

Query: 271 SCEAENSVGAVSASGYLTVYDP----PSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326
            C   NS+G+ SA   +TV       P++++ P++ +++ G      C A G P P + W
Sbjct: 129 MCVGSNSIGSNSAPVKVTVLKADQSFPAVSIQPSTADIQEGQSLELNCVAPGNPPPKVSW 188

Query: 327 ----SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
                +  N  ++  G       ATA   G     +     N S           +G   
Sbjct: 189 WRASGLSSNHQVL--GNQLRILSATAEDSGEYTCRVEGNHGNPS-----------SGGHQ 235

Query: 383 VRGKLTVTSDDDR-PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAW 431
               ++VTS   R   PII   P +  + +   A F C      +P+ + W
Sbjct: 236 ATVSVSVTSSSSRLQSPIIAIEPHSAVVRVGETATFRCRIYSGAQPVRLEW 286



 Score = 83.8 bits (198), Expect = 3e-14
 Identities = 69/233 (29%), Positives = 98/233 (42%), Gaps = 25/233 (10%)

Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVG--------AVSASGYLTVYDPPSINLSPNSV 302
           V+  G L    V  ADEGEY+C+A N+ G         V  SG   +   P + +SP ++
Sbjct: 11  VIRGGVLTFAAVDAADEGEYTCKALNTHGEHVARVSLVVQKSGSGALGSQPQVQVSPQNI 70

Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR-DKYHATAVFDGVTVLTINDT 361
            V  G+  R  C ATG P P + W   G    + P  +R D+         +  L I D 
Sbjct: 71  QVHEGDTLRMYCRATGSPTPRLSWLKNGG---LLPAQARMDR-------TDIGTLLIPDV 120

Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
             +DS  T +C   N  GS+    K+TV    D+  P ++  PS   +         C A
Sbjct: 121 QLSDS-GTYMCVGSNSIGSNSAPVKVTVLK-ADQSFPAVSIQPSTADIQEGQSLELNCVA 178

Query: 422 ICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
              P P ++W+     L  NH+  V  +   +L      DSG YTC     HG
Sbjct: 179 PGNPPPKVSWW-RASGLSSNHQ--VLGNQLRIL-SATAEDSGEYTCRVEGNHG 227



 Score = 83.4 bits (197), Expect = 3e-14
 Identities = 68/252 (26%), Positives = 103/252 (40%), Gaps = 29/252 (11%)

Query: 9   GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
           G  P +   P ++ V       + CRA GSP+P + W K G L+ +         G L  
Sbjct: 58  GSQPQVQVSPQNIQVHEGDTLRMYCRATGSPTPRLSWLKNGGLLPAQARMDRTDIGTLLI 117

Query: 69  LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-----FRLEPESKQSAQGD 123
                    SD+G Y C  +NS G   S +A + V VL+ +       ++P +    +G 
Sbjct: 118 PDVQ----LSDSGTYMCVGSNSIG---SNSAPVKVTVLKADQSFPAVSIQPSTADIQEGQ 170

Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
           ++ L C+ P G+P P V W +        G S  H V G  L I  A   D+G Y C   
Sbjct: 171 SLELNCVAP-GNPPPKVSWWR------ASGLSSNHQVLGNQLRILSATAEDSGEYTCRVE 223

Query: 184 NAAGTRESA--IATLKIHI--------KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233
              G   S    AT+ + +         P +   P   V + G + TF+CR+     P  
Sbjct: 224 GNHGNPSSGGHQATVSVSVTSSSSRLQSPIIAIEPHSAVVRVGETATFRCRIYSGAQPVR 283

Query: 234 LWRRSAGGGNMP 245
           L  + A   ++P
Sbjct: 284 LEWKVANNQHLP 295


>UniRef50_O18465 Cluster: Tractin; n=7; Coelomata|Rep: Tractin -
           Hirudo medicinalis (Medicinal leech)
          Length = 1880

 Score =  146 bits (354), Expect = 3e-33
 Identities = 138/485 (28%), Positives = 195/485 (40%), Gaps = 46/485 (9%)

Query: 18  PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAG-GLFFLRATHGR 75
           P + T    +   + C A G+P    +W+K G  L  S+  R       G   L   +  
Sbjct: 40  PYESTFKNMEEVEIPCEATGTPPLVFQWFKDGEPLEKSEAERPFKDEDQGTITL---YNN 96

Query: 76  VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL--EPESKQSAQGDTVVLECLPPR 133
              D G Y C   N YGTA S    L +AV +E F    EP+      GD + L C PP+
Sbjct: 97  ELKDEGYYQCIVKNKYGTAASVKTLLKMAV-QESFPTVKEPQIVNVRVGDNLTLRCNPPK 155

Query: 134 GSPEPNVYW---KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTD---AGRYQCIARNAAG 187
             P P+VYW   KK  + L  +   R +L   GN    +  + D      Y CI+ N A 
Sbjct: 156 SYPTPDVYWGTVKKGAKLLPLENTMRYNLDYEGNFHFANVMEEDHREGAYYLCISHNNAM 215

Query: 188 TRE------------SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
                          S+   ++ H    + T P   +A TG S   +C   G P P+V W
Sbjct: 216 RSSVQGNDCIIRINGSSKDGVRKHAPGVMWTSPRKDLALTGQSKKLKCIFSGYPTPNVSW 275

Query: 236 RRSAGGGNMPLGRVKVLDD--GSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDP 292
             S  G + P  ++ V  +    L + NV + D G Y C   ++ G AV     LTV   
Sbjct: 276 --SKRGSDFP-PKIVVSSELPHELEIRNVEVGDAGTYRCTGSSTYGKAVFVDIELTVESM 332

Query: 293 P--SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
           P    N  P  VN      A F C   G P PT+ W +        P   R + +     
Sbjct: 333 PRWKDNKPPEDVNTSDEETAVFKCGVEGIPRPTVEWMLNKRPLEDLPPNPRMRMN----- 387

Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP-SNQTL 409
           D  TVLT ++    D +  I C+A N  G       L V ++    PP   + P S   L
Sbjct: 388 DERTVLTFSNVSSKDIQ-VIQCNASNVHGYILANAYLNVFAE----PPSFQDLPVSPMKL 442

Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
                 V  C+    P+P++      + +I   R  V   G L++ +L  SDSG Y C A
Sbjct: 443 TEGKNTVVQCSVFGAPKPLVTC-LRNDTVISGDRFKVDTHGNLLVSNLQLSDSGNYICFA 501

Query: 470 SSRHG 474
           S++ G
Sbjct: 502 SNKFG 506



 Score = 97.1 bits (231), Expect = 3e-18
 Identities = 124/487 (25%), Positives = 194/487 (39%), Gaps = 49/487 (10%)

Query: 15  IEQPLDVTVARHQPATLNCRAGGS-PSPAIRW---YKGGVLV-VSDTHRSILPAGGLFFL 69
           +++P  V V      TL C    S P+P + W    KG  L+ + +T R  L   G F  
Sbjct: 133 VKEPQIVNVRVGDNLTLRCNPPKSYPTPDVYWGTVKKGAKLLPLENTMRYNLDYEGNFHF 192

Query: 70  RATHGRVHSDAGVYWCEATNSY--GTARSRNATLHV-AVLREEFR--------LEPESKQ 118
                  H +   Y C + N+    + +  +  + +    ++  R          P    
Sbjct: 193 ANVMEEDHREGAYYLCISHNNAMRSSVQGNDCIIRINGSSKDGVRKHAPGVMWTSPRKDL 252

Query: 119 SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY 178
           +  G +  L+C+   G P PNV W K G    F     +       L I++    DAG Y
Sbjct: 253 ALTGQSKKLKCIFS-GYPTPNVSWSKRGSD--FPPKIVVSSELPHELEIRNVEVGDAGTY 309

Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLW- 235
           +C   +  G        L +   P       PEDV      +  F+C V G P P V W 
Sbjct: 310 RCTGSSTYGKAVFVDIELTVESMPRWKDNKPPEDVNTSDEETAVFKCGVEGIPRPTVEWM 369

Query: 236 -RRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-DP 292
             +       P  R+++ D+ + L   NV   D     C A N  G + A+ YL V+ +P
Sbjct: 370 LNKRPLEDLPPNPRMRMNDERTVLTFSNVSSKDIQVIQCNASNVHGYILANAYLNVFAEP 429

Query: 293 PSINLSPNS-VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
           PS    P S + +  G      C+  G P+P +  +   N T+I    S D++      D
Sbjct: 430 PSFQDLPVSPMKLTEGKNTVVQCSVFGAPKPLV--TCLRNDTVI----SGDRFKV----D 479

Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
               L +++   +DS N I C A N  G+  V   L V    +     I+  PS+    +
Sbjct: 480 THGNLLVSNLQLSDSGNYI-CFASNKFGNDSVGANLIVRRRTE-----ISRPPSDHVTTV 533

Query: 412 KSMAVFPCTAICTPEP----IIAWYFEGEAL-IQNHRRNVTN--DGTLVLKDLDKSDSGT 464
            S  V  C A   PE      + W  +GE +  +     V +  D +L +K ++  +SGT
Sbjct: 534 GSEVVLHCNATTDPEEKNSLSVKWLKDGEPITFEGSSPGVFDFRDNSLTIKKVEVKESGT 593

Query: 465 YTCVASS 471
           Y C+AS+
Sbjct: 594 YVCIAST 600



 Score = 83.4 bits (197), Expect = 3e-14
 Identities = 108/379 (28%), Positives = 144/379 (37%), Gaps = 24/379 (6%)

Query: 27  QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
           Q   L C   G P+P + W K G    SD    I+ +  L            DAG Y C 
Sbjct: 257 QSKKLKCIFSGYPTPNVSWSKRG----SDFPPKIVVSSELPHELEIRNVEVGDAGTYRCT 312

Query: 87  ATNSYGTARSRNATLHVAVL-REEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
            +++YG A   +  L V  + R +    PE   ++  +T V +C    G P P V W  N
Sbjct: 313 GSSTYGKAVFVDIELTVESMPRWKDNKPPEDVNTSDEETAVFKC-GVEGIPRPTVEWMLN 371

Query: 146 GQTLL-FDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY 203
            + L     + RM + D    L   +    D    QC A N  G    A A L +  +P 
Sbjct: 372 KRPLEDLPPNPRMRMNDERTVLTFSNVSSKDIQVIQCNASNVHGYI-LANAYLNVFAEPP 430

Query: 204 LITG-PEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDN 261
                P   +  T G +   QC V G P P V   R+     +   R KV   G+L + N
Sbjct: 431 SFQDLPVSPMKLTEGKNTVVQCSVFGAPKPLVTCLRN--DTVISGDRFKVDTHGNLLVSN 488

Query: 262 VILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPE 321
           + L+D G Y C A N  G  S    L V     I+  P+      G+     C AT  PE
Sbjct: 489 LQLSDSGNYICFASNKFGNDSVGANLIVRRRTEISRPPSDHVTTVGSEVVLHCNATTDPE 548

Query: 322 PTMFWSV---EGNRTIIFPGMSRDKYHATAVFD-GVTVLTINDTDKNDSRNTIVCSAVNY 377
                SV   +    I F G S        VFD     LTI   +  +S  T VC A   
Sbjct: 549 EKNSLSVKWLKDGEPITFEGSS------PGVFDFRDNSLTIKKVEVKES-GTYVCIASTD 601

Query: 378 AGSSFVRGKLTVTSDDDRP 396
             S  +  +L V    D P
Sbjct: 602 LDSDNITVELVVKGVPDPP 620



 Score = 50.4 bits (115), Expect = 3e-04
 Identities = 25/91 (27%), Positives = 41/91 (45%), Gaps = 3/91 (3%)

Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNV 446
           +T   + +RPP I  + P   T         PC A  TP  +  W+ +GE L ++     
Sbjct: 23  MTFQKEVNRPPSITAHPPYESTFKNMEEVEIPCEATGTPPLVFQWFKDGEPLEKSEAERP 82

Query: 447 TND---GTLVLKDLDKSDSGTYTCVASSRHG 474
             D   GT+ L + +  D G Y C+  +++G
Sbjct: 83  FKDEDQGTITLYNNELKDEGYYQCIVKNKYG 113



 Score = 50.0 bits (114), Expect = 4e-04
 Identities = 55/239 (23%), Positives = 90/239 (37%), Gaps = 16/239 (6%)

Query: 253 DDGSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINL--SPNSVNVESGNV 309
           D G++ L N  L DEG Y C  +N  G A S    L +    S      P  VNV  G+ 
Sbjct: 87  DQGTITLYNNELKDEGYYQCIVKNKYGTAASVKTLLKMAVQESFPTVKEPQIVNVRVGDN 146

Query: 310 ARFTCTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG-VTVLTINDTDKNDSR 367
               C      P P ++W        + P  +  +Y+    ++G      + + D  +  
Sbjct: 147 LTLRCNPPKSYPTPDVYWGTVKKGAKLLPLENTMRYNLD--YEGNFHFANVMEEDHREGA 204

Query: 368 NTIVCSAVNYAGSSFVRG-----KLTVTSDDD---RPPPIITNGPSNQTLPIKSMAVFPC 419
             + C + N A  S V+G     ++  +S D      P ++   P              C
Sbjct: 205 YYL-CISHNNAMRSSVQGNDCIIRINGSSKDGVRKHAPGVMWTSPRKDLALTGQSKKLKC 263

Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVW 478
                P P ++W   G         +      L +++++  D+GTY C  SS +GK V+
Sbjct: 264 IFSGYPTPNVSWSKRGSDFPPKIVVSSELPHELEIRNVEVGDAGTYRCTGSSTYGKAVF 322


>UniRef50_O01761 Cluster: Muscle M-line assembly protein unc-89; n=12;
            Caenorhabditis|Rep: Muscle M-line assembly protein unc-89
            - Caenorhabditis elegans
          Length = 8081

 Score =  146 bits (354), Expect = 3e-33
 Identities = 178/689 (25%), Positives = 281/689 (40%), Gaps = 110/689 (15%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAG 64
            VT+ + P    +  DV     QP  L C+   SP P + WYK G +V  SD  +  L   
Sbjct: 5695 VTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPD 5754

Query: 65   GLFFLRATHGRVHSDAGVYWCEATNSYGTARS----------RNATLHVAVLREEFR--- 111
            G+  L      V+ D G+Y   ATN  GTA+           R++    +  R+ F    
Sbjct: 5755 GVATLLIP-SCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGARRSADRDVFDANK 5813

Query: 112  ----LEP-ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-- 164
                +EP E+ +  +  +  L C    G P+P + W K+G+ +   G  R+ L++  +  
Sbjct: 5814 APKLMEPLENIRIPEKQSFRLRC-KFSGDPKPTIKWFKDGERVFPYG--RLQLIESPDGV 5870

Query: 165  --LVIQDARQTDAGRYQCIARNAAGTRESA--IATLKIHIKPYLI------------TGP 208
              LV+  A + DAG Y+C+A N  G+  ++  +  ++   KP  I            T P
Sbjct: 5871 CELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTP 5930

Query: 209  EDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDGSLRL--DNVI 263
              +  A+ G SVTF+C   G+P P + W +  G       ++K+    DG+ RL   +V 
Sbjct: 5931 LTIRRAKPGDSVTFECLPFGNPFPSIKWLKD-GLELFSDEKIKMEAAADGTQRLILSDVT 5989

Query: 264  LADEGEYSCEAENSVGAVSASGYLTVYDP--------PSINLSPN-----------SVNV 304
               EG + C A N  G  S    L +           P +N  P            ++++
Sbjct: 5990 FLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGEPEECKPRIRRGLYNMSI 6049

Query: 305  ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
              GNV      ATG P PT+ W  +G + I+  G    +   T    G+  L I +   +
Sbjct: 6050 HEGNVVEMIVCATGIPTPTVKWYKDG-QEIVGDGPDGKRVIFTDE-RGIHHLVIVNASPD 6107

Query: 365  DSRNTIVCSAVNYAGSSFVRGKLT------VTSDDDRP----PPIITNGPSNQTLPIKSM 414
            D        A N  GS+   G L       +   D+R     PP       N+ +     
Sbjct: 6108 D-EGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFVRQLKNKHVFNHMP 6166

Query: 415  AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG----TLVLKDLDKSDSGTYTCVAS 470
             +F C  +  P P + W+  G+ ++   R  + + G     L++ D    D+G Y   A 
Sbjct: 6167 TIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIILDTTLEDAGEYVATAK 6226

Query: 471  SRHGKYVWSGALLVDSPINPNIHF---------------FRAADVSSLPGPPTK-PITHN 514
            + HG    S  L V  P   +I F               F+  + +SLP PP + P    
Sbjct: 6227 NSHGSASSSAVLDVTVPFLDSIKFNGEIDVTPYLTEEYGFKKLNTASLPTPPDRGPFIKE 6286

Query: 515  VTDTSVTLSWSQNNKIGSS-SILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYV 573
            VT   +TLSW    +       + Y +E+  RE           + W ++   + +    
Sbjct: 6287 VTGHYLTLSWIPTKRAPPRYPQVTYVIEI--REL--------PEKQWSLLEYNIPEPVCK 6336

Query: 574  VKSLIPGITYMFIVRTENSHGLSGPSPVS 602
            V++L  G +Y F VR EN +G+S PSP S
Sbjct: 6337 VRNLELGKSYQFRVRAENIYGISDPSPAS 6365



 Score =  140 bits (339), Expect = 2e-31
 Identities = 139/499 (27%), Positives = 208/499 (41%), Gaps = 62/499 (12%)

Query: 28   PATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL-PAGGLFFLRATHGRVHSDAGVYWCE 86
            P  + C    +P+  + W+K G  +    H  I     G   ++       SD GVY C 
Sbjct: 5293 PMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIKIIPFE-ESDIGVYMCV 5351

Query: 87   ATNSYGTARSRNATLHVAVL-------REEF--RLEP--ESKQSAQGDTVVLECLPPRGS 135
            A N  G A ++ AT  V +L       R E+  ++ P  E K    G  + L C      
Sbjct: 5352 AVNELGQAETQ-ATYQVEILEHVEEEKRREYAPKINPPLEDKTVNGGQPIRLSC-KVDAI 5409

Query: 136  PEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGT-RESA 192
            P  +V W K+G  L  D  + +   + G   L I D+ + D G Y+C+A NA GT   S 
Sbjct: 5410 PRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINTSC 5469

Query: 193  IATLKI---HIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG-GGN 243
               +K+    +K     P+   G  D+ A  G S T +C V GDP P++ W R+     N
Sbjct: 5470 SVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRN 5529

Query: 244  MPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY----------- 290
             P   ++   DG  SL ++   ++DEG Y CEAEN+ G         V            
Sbjct: 5530 GPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKM 5589

Query: 291  ---DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
                PP   L  + ++V  GNV    C  TG P P++ WS +G   I     SR ++ + 
Sbjct: 5590 DEGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLI---EDSRFEW-SN 5645

Query: 348  AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT-NGPSN 406
                GV  L I +   +D   T  C A N  GS+    K  V  DD     ++T + P  
Sbjct: 5646 EASKGVYQLRIKNATVHD-EGTYRCVATNENGSATT--KSFVRMDDGLGSGVVTASQPPR 5702

Query: 407  QTLPIKSMAV-------FPCTAICTPEPIIAWYFEGEALIQNHRRNV--TNDG--TLVLK 455
             TL +  +           C    +P P + WY +G  +  + R  +  + DG  TL++ 
Sbjct: 5703 FTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDGVATLLIP 5762

Query: 456  DLDKSDSGTYTCVASSRHG 474
                 D G Y  +A++  G
Sbjct: 5763 SCVYDDDGIYRVIATNPSG 5781



 Score =  139 bits (336), Expect = 5e-31
 Identities = 142/521 (27%), Positives = 221/521 (42%), Gaps = 71/521 (13%)

Query: 15   IEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
            I  PL D TV   QP  L+C+    P  ++ WYK G+ + +D+  SI          A +
Sbjct: 5385 INPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAIN 5444

Query: 74   GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK---------QSAQGDT 124
                 D G Y C ATN++GT  + + +++V V ++E + E E            + +GD+
Sbjct: 5445 DSTEEDIGAYRCVATNAHGTINT-SCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDS 5503

Query: 125  VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM--HLVDGG-NLVIQDARQTDAGRYQCI 181
              L+C    G P P + W +NGQ LL +G   +     DG  +L + ++  +D G Y+C 
Sbjct: 5504 FTLKC-AVTGDPFPEIKWYRNGQ-LLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCE 5561

Query: 182  ARNAAG-TRESAIATLKIHI----KPYLITGP--------EDVVAQTGSSVTFQCRVGGD 228
            A NA G  +  A A +++ +    KP +  G          D+    G+ +  +C+V G 
Sbjct: 5562 AENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGL 5621

Query: 229  PLPDVLWRRSAGGGNMPLGRVKVLDDGS-----LRLDNVILADEGEYSCEAENSVGAVS- 282
            P P V W +  GG  +   R +  ++ S     LR+ N  + DEG Y C A N  G+ + 
Sbjct: 5622 PNPSVKWSKD-GGPLIEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATT 5680

Query: 283  ----------ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332
                       SG +T   PP   L    V    G   +  C     P P M W  +G  
Sbjct: 5681 KSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDG-- 5738

Query: 333  TIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV--- 389
             I+ P    D+   +   DGV  L I     +D     V  A N +G++  +G  TV   
Sbjct: 5739 AIVTPS---DRIQISLSPDGVATLLIPSCVYDDDGIYRVI-ATNPSGTAQDKGTATVKKL 5794

Query: 390  --------TSD----DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437
                    ++D    D    P +     N  +P K      C     P+P I W+ +GE 
Sbjct: 5795 PRDSGARRSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGER 5854

Query: 438  LIQNHRRNV--TNDGT--LVLKDLDKSDSGTYTCVASSRHG 474
            +    R  +  + DG   LV+    + D+G Y CVA + +G
Sbjct: 5855 VFPYGRLQLIESPDGVCELVVDSATRQDAGGYRCVAENTYG 5895



 Score =  136 bits (328), Expect = 5e-30
 Identities = 127/499 (25%), Positives = 210/499 (42%), Gaps = 32/499 (6%)

Query: 7    TSGEAPYIIEQPLDVT-VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL--PA 63
            T  EAP + EQ L  T V   +   +  + GGS +P + W+K    V  D +  +   P 
Sbjct: 3184 TKVEAP-VFEQGLKKTSVKEKEEIKMEVKVGGS-APDVEWFKDDKPVSEDGNHEMKKNPE 3241

Query: 64   GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQG 122
             G+F L        +DAG Y  +A+N  GTA S   A +  ++ +  F  E  + +    
Sbjct: 3242 TGVFTLVVKQAAT-TDAGKYTAKASNPAGTAESSAEAEVTQSLEKPTFVRELVTTEVKIN 3300

Query: 123  DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG---NLVIQDARQTDAGRYQ 179
            +T  L  +  +G P+P+V W K+GQ +  D    +  V+G    ++ I+DAR  D+G+Y 
Sbjct: 3301 ETATLS-VTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYA 3359

Query: 180  CIARNAAGTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
            C A N AG    E+  A +K  + P  +     +  +   S T   +V G P P V W +
Sbjct: 3360 CRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFK 3419

Query: 238  SAGGGNMP----LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYD- 291
                 ++     + +   +   SL +++    D G YSC A N  G A++ + +  + D 
Sbjct: 3420 DDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRARNEAGEALTTANFGIIRDS 3479

Query: 292  -PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
             PP        + V          T  G P P + W  + ++ I    +      A    
Sbjct: 3480 IPPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEW-FKDDKPI---NIDNSHIFAKDEG 3535

Query: 351  DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
             G   LTI    + +      C A N AG +     + V  + + P  +   G     + 
Sbjct: 3536 SGHHTLTIKQA-RGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAP--LFVQGLKPYEVE 3592

Query: 411  IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-----TLVLKDLDKSDSGTY 465
                A         PEP + W+ +G  +  +++  +   G     TLV+KD + +D G Y
Sbjct: 3593 QGKPAELVVRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLVIKDTNNADFGKY 3652

Query: 466  TCVASSRHGKYVWSGALLV 484
            TC A+++ GK    G L +
Sbjct: 3653 TCQATNKAGKDETVGELKI 3671



 Score =  135 bits (327), Expect = 6e-30
 Identities = 129/483 (26%), Positives = 199/483 (41%), Gaps = 34/483 (7%)

Query: 29   ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
            A +  +  G P P I WYK  V +  D   +       FF         +D G Y C AT
Sbjct: 565  AKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCMAT 624

Query: 89   NSYGTARSRNATLHVAVLREE-----FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWK 143
            N YG A S +A   V  + +E     F  +   K+  +GD +  EC    G PEP + W 
Sbjct: 625  NEYGQA-STSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFEC-EVEGWPEPELVWL 682

Query: 144  KNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGTRESAIATL----- 196
             + Q L    D R+   DG    L I+DA+  D G Y    +N  G+ ES          
Sbjct: 683  VDDQPLRPSHDFRLQ-YDGQTAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADP 741

Query: 197  -KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK-VLDD 254
             K H+ P      E V    G  V F+  + GDP P+++W  + G       +VK + +D
Sbjct: 742  DKNHVAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFIN-GKPLSESEKVKFISED 800

Query: 255  G--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---DPPSINLSPNSVNVESGNV 309
            G   L + +V    +G  +C+  N +G+ S  G L V     PP+ N       V+  + 
Sbjct: 801  GICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDKTVQEKST 860

Query: 310  ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
              F    +G PEPT+ +++ G         + ++       DG   ++I +T  +     
Sbjct: 861  VVFEVDVSGWPEPTLTFTLCGKEL-----KNGEEGVEIVGHDGFYRISIPNTSMDKHDGE 915

Query: 370  IVCSAVNYAGSSFVRGKLTVTSDDD--RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427
            IV  A N  G++  R +LTV  +++  R  P       +QT+     AVF  T    P P
Sbjct: 916  IVAKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNP 975

Query: 428  IIAWYFEGEALIQNH---RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
             + W+  G  + Q     +    N    +  D     +GT  C A +  G++     L+V
Sbjct: 976  EVTWFINGHKMDQGSPGVKIEAHNHDHKLTID-SAQYAGTVLCRAENAVGRFETKARLVV 1034

Query: 485  DSP 487
             +P
Sbjct: 1035 LAP 1037



 Score =  126 bits (303), Expect = 5e-27
 Identities = 139/544 (25%), Positives = 222/544 (40%), Gaps = 78/544 (14%)

Query: 9    GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
            GE P+  +  +D+   R    TL C   G P P I+WY+ G L+ +     I  +     
Sbjct: 5484 GEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSC 5543

Query: 69   LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV--AVLREE-----------FRLEPE 115
                +    SD G+Y CEA N++G A+++ AT HV  A+ + E           F LE  
Sbjct: 5544 SLTVNESTMSDEGIYRCEAENAHGKAKTQ-ATAHVQMALGKTEKPKMDEGKPPKFILELS 5602

Query: 116  SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-----LVIQDA 170
                + G+ + LEC    G P P+V W K+G  L+   DSR    +  +     L I++A
Sbjct: 5603 DMSVSLGNVIDLEC-KVTGLPNPSVKWSKDGGPLI--EDSRFEWSNEASKGVYQLRIKNA 5659

Query: 171  RQTDAGRYQCIARNAAGTRES-AIATLKIHIKPYLITGPE---------DVVAQTGSSVT 220
               D G Y+C+A N  G+  + +   +   +   ++T  +         DV    G  + 
Sbjct: 5660 TVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTTEGQPLK 5719

Query: 221  FQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDG--SLRLDNVILADEGEYSCEAEN 276
             +C+V   PLP+++W +  G    P  R+++    DG  +L + + +  D+G Y   A N
Sbjct: 5720 LECKVDASPLPEMVWYKD-GAIVTPSDRIQISLSPDGVATLLIPSCVYDDDGIYRVIATN 5778

Query: 277  SVGAVSASGYLTVYDPP--------------SINLSP------NSVNVESGNVARFTCTA 316
              G     G  TV   P                N +P       ++ +      R  C  
Sbjct: 5779 PSGTAQDKGTATVKKLPRDSGARRSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKF 5838

Query: 317  TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
            +G P+PT+ W  +G R  +FP     +       DGV  L ++   + D+     C A N
Sbjct: 5839 SGDPKPTIKWFKDGER--VFP---YGRLQLIESPDGVCELVVDSATRQDA-GGYRCVAEN 5892

Query: 377  YAGSSFVRGKLTVTSDDDRPPPI---ITNGPS-NQTLPIK-------SMAVFPCTAICTP 425
              GS+     + V   D +P  I   I  G +   T P+            F C     P
Sbjct: 5893 TYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTPLTIRRAKPGDSVTFECLPFGNP 5952

Query: 426  EPIIAWYFEGEALIQNH--RRNVTNDGT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
             P I W  +G  L  +   +     DGT  L+L D+     G + CVA++ HG       
Sbjct: 5953 FPSIKWLKDGLELFSDEKIKMEAAADGTQRLILSDVTFLSEGYFRCVATNEHGTASTKAE 6012

Query: 482  LLVD 485
            L+++
Sbjct: 6013 LVIE 6016



 Score =  124 bits (298), Expect = 2e-26
 Identities = 126/498 (25%), Positives = 203/498 (40%), Gaps = 46/498 (9%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI--LPAGGLF 67
            E P  + + +   V  ++ ATL+    G P P++ W K G  V +D+   I  +   G +
Sbjct: 3284 EKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSY 3343

Query: 68   FLRATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEF--RLEPESKQSAQGDT 124
             +     R+  D+G Y C ATN  G A++  N  +   ++  EF  +L P   +  +  T
Sbjct: 3344 SITIKDARLE-DSGKYACRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKEKESTT 3402

Query: 125  VVLECLPPRGSPEPNVYWKKNGQTLLFDGD---SRMHLVDGGNLVIQDARQTDAGRYQCI 181
            + ++ +   G+PEP+V W K+   +  D      +   V   +L I DARQ D G Y C 
Sbjct: 3403 LSVKVV---GTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCR 3459

Query: 182  ARNAAG--TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
            ARN AG     +    ++  I P        +  +   ++  +  V G P+P+V W +  
Sbjct: 3460 ARNEAGEALTTANFGIIRDSIPPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEWFKDD 3519

Query: 240  GGGNMPLGRVKVLDDGS----LRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDP 292
               N+    +   D+GS    L +      D G Y+C+A N  G    +  + V    + 
Sbjct: 3520 KPINIDNSHIFAKDEGSGHHTLTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEA 3579

Query: 293  PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV--F 350
            P          VE G  A       G+PEP + W  +G    I      D  H       
Sbjct: 3580 PLFVQGLKPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAI------DNQHVIEKKGE 3633

Query: 351  DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV--------TSDDDRPPPIITN 402
            +G   L I DT+  D      C A N AG     G+L +        T+++ +P   +  
Sbjct: 3634 NGSHTLVIKDTNNADF-GKYTCQATNKAGKDETVGELKIPKYSFEKQTAEEVKP---LFI 3689

Query: 403  GPSNQTLPIK-SMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRR-NVTNDGT--LVLKDL 457
             P  +T  ++    V  C       P I ++   + + I  H +  V  DG   L +++ 
Sbjct: 3690 EPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNIKLTIQNA 3749

Query: 458  DKSDSGTYTCVASSRHGK 475
             K D G Y C A +  GK
Sbjct: 3750 KKEDVGAYRCEAVNVAGK 3767



 Score =  112 bits (270), Expect = 5e-23
 Identities = 127/493 (25%), Positives = 204/493 (41%), Gaps = 39/493 (7%)

Query: 7    TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGG 65
            T   AP  +E     TV   Q A L C+  G P P I+W K G  V +S   R+     G
Sbjct: 3812 TGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDG 3871

Query: 66   LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---- 121
               L        +DAG Y CEA N YG+A +      +  L    +++ E+    Q    
Sbjct: 3872 TLTL-TFDNVTQADAGEYRCEAENEYGSAWTEGPI--IVTLEGAPKIDGEAPDFLQPVKP 3928

Query: 122  -----GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTD 174
                 G+T VLE     G P+P+V W KNG+ L      ++  +D G   L + +A+  D
Sbjct: 3929 AVVTVGETAVLEG-KISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLTVTNAKLDD 3987

Query: 175  AGRYQCIARNAAGTRESAIA-TLK--IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231
               Y+C A N  G   S +  T+K    + P        +  +   +  F+C+V G   P
Sbjct: 3988 MDEYRCEASNEFGDVWSDVTLTVKEPAQVAPGFFKELSAIQVKETETAKFECKVSGTK-P 4046

Query: 232  DVLWRRSAGGGNMPLGRV--KVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYL 287
            DV W +  G       RV  +  DDG+ RL  ++    D+G Y  E  N  G  ++   L
Sbjct: 4047 DVKWFKD-GTPLKEDKRVHFESTDDGTQRLVIEDSKTDDQGNYRIEVSNDAGVANSKVPL 4105

Query: 288  TVYDPPSINLSP--NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345
            TV    ++ +      VNV  G     +    G+P+ T+ W  +G  T+     S     
Sbjct: 4106 TVVPSETLKIKKGLTDVNVTQGTKILLSVEVEGKPK-TVKW-YKGTETV----TSSQTTK 4159

Query: 346  ATAVFDGVTVLTINDTDKNDS-RNTIVCSAVNYAGSSFVRGKLTVTSDDDR-PPPIITNG 403
               V +    L I   + +D+    +V S  +++  S     +TVT   ++   P    G
Sbjct: 4160 IVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVES--SATVTVTKAAEKISLPSFKKG 4217

Query: 404  PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDS 462
             ++Q++P  +  V        P+  + WY  G+ +      ++ N    L + D  + D 
Sbjct: 4218 LADQSVPKGTPLVLEVEIEGKPKD-VKWYKNGDEIKDGKVEDLGNGKYRLTIPDFQEKDV 4276

Query: 463  GTYTCVASSRHGK 475
            G Y+  A++  G+
Sbjct: 4277 GEYSVTAANEAGE 4289



 Score =  107 bits (257), Expect = 2e-21
 Identities = 120/492 (24%), Positives = 196/492 (39%), Gaps = 35/492 (7%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P +++ P  VT+   + A       G P+P ++W     +V      + +    ++ L+ 
Sbjct: 2075 PIVVDGPKSVTIKETETAEFKATISGFPAPTVKWTINEKIVEESRTITTIKTEDVYTLKI 2134

Query: 72   THGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGDTVVLEC 129
            ++ ++    G     A NS G   S+ A L V   V   +F+ +   K + +G+ +    
Sbjct: 2135 SNAKI-EQTGTVKVTAQNSAG-QDSKQADLKVEPNVKAPKFKSQLTDKVADEGEPLRWNL 2192

Query: 130  LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG----NLVIQDARQTDAGRYQCIARNA 185
                 SP   V W  NGQ L       + +VD G    ++ I +A+   +G     A+NA
Sbjct: 2193 ELDGPSPGTEVSWLLNGQPL--TKSDTVQVVDHGDGTYHVTIAEAKPEMSGTLTAKAKNA 2250

Query: 186  AGTRE-SAIATLK-IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSA 239
            AG  E SA  T+   + KP  +  P++       SV F   V G P+P+V W    ++  
Sbjct: 2251 AGECETSAKVTVNGGNKKPEFVQAPQNHETTLEESVKFSAIVTGKPMPNVTWYLNNKKLI 2310

Query: 240  GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDPPSIN 296
                + +  V      S+R+   ++   G    EAEN  G V A+  L V    + P   
Sbjct: 2311 QSEEVKVKYVHETGKTSIRIQKPLMEHNGTIRVEAENVSGKVQATAQLKVDKKTEVPKFT 2370

Query: 297  LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS-RDKYHATAVFDGVTV 355
             + +   V+ G   +FT    G PEP++ W++ G      P ++  DK       DG   
Sbjct: 2371 TNMDDRQVKEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHPNITVTDK-------DGEHT 2423

Query: 356  LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
            + I+     +    + C A N  GS     +L V    D   P       ++ +    + 
Sbjct: 2424 IEISAVTP-EQAGELSCEATNPVGSKKRDVQLAVKKVGD--APTFAKNLEDRLITEGELT 2480

Query: 416  VFPCTA-ICTPEPIIAWYFEG-EALIQNHRRNV-TNDGTLVLKDLDK--SDSGTYTCVAS 470
            +      I  P+P I W  +G E     H + V   DG+L L  L     D G  T  A 
Sbjct: 2481 LMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAE 2540

Query: 471  SRHGKYVWSGAL 482
            S  G    S +L
Sbjct: 2541 SEFGVAECSASL 2552



 Score =  106 bits (255), Expect = 3e-21
 Identities = 116/490 (23%), Positives = 195/490 (39%), Gaps = 39/490 (7%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            +AP  I    D T    +   L C+  G P P + W      +  ++  ++    G+  +
Sbjct: 2992 KAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQES-ITVESVEGVERV 3050

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
              T   + S  G Y C A N+ GT+++  A L V      F  E ++K+ + G+ +VL C
Sbjct: 3051 TITSSEL-SHQGKYTCIAENTEGTSKT-EAFLTVQGEAPVFTKELQNKELSIGEKLVLSC 3108

Query: 130  LPPRGSPEPNVYWKKNGQTLLFD----GDSRMHLV-DGGN----LVIQDARQTDAGRYQC 180
               +GSP+P+V +    +T   +      SR+ +  D  N    +VI    + D   Y+ 
Sbjct: 3109 -SVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDIVSYKA 3167

Query: 181  IARNAAGTRES-AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS- 238
            IA N+ GT  S +  T K+   P    G +    +    +  + +VGG   PDV W +  
Sbjct: 3168 IATNSIGTATSTSKITTKVE-APVFEQGLKKTSVKEKEEIKMEVKVGGS-APDVEWFKDD 3225

Query: 239  ---AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDP 292
               +  GN  + +       +L +      D G+Y+ +A N  G   +S    V    + 
Sbjct: 3226 KPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQSLEK 3285

Query: 293  PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD- 351
            P+      +  V+    A  + T  G P+P++ W  +G        +  D  H  A  + 
Sbjct: 3286 PTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQ------PVQTDSSHVIAKVEG 3339

Query: 352  -GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
             G   +TI D    DS     C A N AG +       V    +  PP      S   + 
Sbjct: 3340 SGSYSITIKDARLEDS-GKYACRATNPAGEAKTEANFAVVK--NLVPPEFVEKLSPLEVK 3396

Query: 411  IKSMAVFPCTAICTPEPIIAWYFEGEAL-IQN----HRRNVTNDGTLVLKDLDKSDSGTY 465
             K         + TPEP + W+ +   + I N     ++      +L + D  + D G Y
Sbjct: 3397 EKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIY 3456

Query: 466  TCVASSRHGK 475
            +C A +  G+
Sbjct: 3457 SCRARNEAGE 3466



 Score =  104 bits (249), Expect = 2e-20
 Identities = 126/505 (24%), Positives = 191/505 (37%), Gaps = 36/505 (7%)

Query: 9    GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
            GEAP   ++  +  ++  +   L+C   GSP P + +Y        +T  +      +  
Sbjct: 3084 GEAPVFTKELQNKELSIGEKLVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEH 3143

Query: 69   LRA-THGRV------HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
             +  TH R+        D   Y   ATNS GTA S   T  +    E    E   K+++ 
Sbjct: 3144 DQTNTHWRMVISQITKEDIVSYKAIATNSIGTATS---TSKITTKVEAPVFEQGLKKTSV 3200

Query: 122  GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL-VDGG--NLVIQDARQTDAGRY 178
             +   ++     G   P+V W K+ + +  DG+  M    + G   LV++ A  TDAG+Y
Sbjct: 3201 KEKEEIKMEVKVGGSAPDVEWFKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKY 3260

Query: 179  QCIARNAAGTRES---AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
               A N AGT ES   A  T  +  KP  +        +   + T    V G P P V W
Sbjct: 3261 TAKASNPAGTAESSAEAEVTQSLE-KPTFVRELVTTEVKINETATLSVTVKGVPDPSVEW 3319

Query: 236  RRSAGGGNMPLGRV--KVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
             +           V  KV   G  S+ + +  L D G+Y+C A N  G         V  
Sbjct: 3320 LKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVK 3379

Query: 292  ---PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
               PP      + + V+       +    G PEP++ W  +     I       K  A  
Sbjct: 3380 NLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVG 3439

Query: 349  VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408
             F     LTIND  + D      C A N AG +       +  D    PP  T       
Sbjct: 3440 SFS----LTINDARQGDV-GIYSCRARNEAGEALTTANFGIIRDS--IPPEFTQKLRPLE 3492

Query: 409  LPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDG----TLVLKDLDKSDSG 463
            +  +       T I TP P + W+ + + + I N      ++G    TL +K     D G
Sbjct: 3493 VREQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQARGEDVG 3552

Query: 464  TYTCVASSRHGKYVWSGALLVDSPI 488
             YTC A++  G+   +  + V   I
Sbjct: 3553 VYTCKATNEAGEAKTTANMAVQEEI 3577



 Score =  102 bits (245), Expect = 5e-20
 Identities = 117/404 (28%), Positives = 165/404 (40%), Gaps = 33/404 (8%)

Query: 11   APYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFF 68
            AP    +PL D TV             G P P + +   G  L   +    I+   G + 
Sbjct: 842  APPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYR 901

Query: 69   LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP------ESKQSAQG 122
            +   +  +    G    +A N +GTA SR A L V    EE R  P      E +    G
Sbjct: 902  ISIPNTSMDKHDGEIVAKAQNEHGTAESR-ARLTVEQEEEESRSAPTFLKDIEDQTVKTG 960

Query: 123  DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN----LVIQDARQTDAGRY 178
            +  V E    RG+P P V W  NG  +  D  S    ++  N    L I  A+   AG  
Sbjct: 961  EFAVFETTV-RGNPNPEVTWFINGHKM--DQGSPGVKIEAHNHDHKLTIDSAQY--AGTV 1015

Query: 179  QCIARNAAGTRES-----AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233
             C A NA G  E+      +A  K    P  +    D      ++V F+ RV G+P P V
Sbjct: 1016 LCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTV 1075

Query: 234  LWRRSAGGGNMPLGRVKVLD-DGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVY 290
             W    G       RV++ + DGS+++   N+ + D GE    A NS G+      LTV 
Sbjct: 1076 TWYLK-GEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQ 1134

Query: 291  DPP---SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
              P     +L P S+ VE G+ A F+  A G P PT  WSV G +       +R     +
Sbjct: 1135 KKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWSVNGRKVRDGQEGARVTRDES 1194

Query: 348  AVFDGVTVLTINDTDKNDSRNTIVCSAV--NYAGSSFVRGKLTV 389
             V DG ++LTI+        N +  S V  N  G+     +LT+
Sbjct: 1195 TV-DGASILTIDTATYYSEVNHLTISVVAENTLGAEETGAQLTI 1237



 Score = 99.5 bits (237), Expect = 5e-19
 Identities = 125/500 (25%), Positives = 188/500 (37%), Gaps = 54/500 (10%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA-GGLFFLRATHGRVHS 78
            D  V      TL C   G P P + W K GV++  D   ++  A  G   LR    +  S
Sbjct: 5079 DTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAK-KS 5137

Query: 79   DAGVYWCEATNSYGTARSRNATLHVAVLREE-----FRLEPESKQSAQGDTVVLECLPPR 133
            D G Y   A N  G+A S +  + V    E+     F +  ++  +  GD      +  R
Sbjct: 5138 DIGQYRVTAKNEAGSATS-DCKVTVTEQGEQPSKPKFVIPLKTGAALPGDKKEFN-VKVR 5195

Query: 134  GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRES 191
            G P+P + W  NG  + FD    +  +  GN  L I+D R+ D G  +CIA+N  GT E+
Sbjct: 5196 GLPKPTLQWFLNGIPIKFDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENGTDET 5255

Query: 192  AIATLK-----------IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
                 +           +   P       D     G  +  +C V  +P  +V W +   
Sbjct: 5256 VCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGK 5315

Query: 241  G-GNMPLGRVKVLDDGSLRLDNVIL--ADEGEYSCEAENSVG--AVSASGYLTVYD---- 291
               +     ++   DG+ R+  +    +D G Y C A N +G     A+  + + +    
Sbjct: 5316 KIEHTAHTEIRNTVDGACRIKIIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEE 5375

Query: 292  ------PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345
                   P IN       V  G   R +C     P  ++ W  +G      P  +  +  
Sbjct: 5376 EKRREYAPKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDG-----LPLRADSRTS 5430

Query: 346  ATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG----SSFVRGKLTVTS-DDDRPPPII 400
                 DG   L IND+ + D      C A N  G    S  V  K+       +   P  
Sbjct: 5431 IQYEEDGTATLAINDSTEEDI-GAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFF 5489

Query: 401  TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNV---TNDG--TLVLK 455
            T G  +            C     P P I WY  G+ L++N  R V   + DG  +L + 
Sbjct: 5490 TKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQ-LLRNGPRTVIETSPDGSCSLTVN 5548

Query: 456  DLDKSDSGTYTCVASSRHGK 475
            +   SD G Y C A + HGK
Sbjct: 5549 ESTMSDEGIYRCEAENAHGK 5568



 Score = 97.5 bits (232), Expect = 2e-18
 Identities = 118/443 (26%), Positives = 172/443 (38%), Gaps = 64/443 (14%)

Query: 4    DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
            D   + +AP ++E   ++ +   Q   L C+  G P P I+W+K G  V       ++ +
Sbjct: 5807 DVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIES 5866

Query: 64   GGLFFLRATHGRVHSDAGVYWCEATNSYGTARS----------RNATLHVAVLRE----E 109
                           DAG Y C A N+YG+AR+          R      + +RE     
Sbjct: 5867 PDGVCELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPG 5926

Query: 110  FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVI 167
            F      +++  GD+V  ECL P G+P P++ W K+G  L  D   +M     G   L++
Sbjct: 5927 FTTPLTIRRAKPGDSVTFECL-PFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQRLIL 5985

Query: 168  QDARQTDAGRYQCIARNAAGTRESAIATLKI-------------------HIKPYLITGP 208
             D      G ++C+A N  GT  S  A L I                     KP +  G 
Sbjct: 5986 SDVTFLSEGYFRCVATNEHGT-ASTKAELVIEGDRTIGSRPLPEVNGEPEECKPRIRRGL 6044

Query: 209  EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPLGRVKVLDD----GSLRLDNV 262
             ++    G+ V       G P P V W +      G+ P G+  +  D      L + N 
Sbjct: 6045 YNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDERGIHHLVIVNA 6104

Query: 263  ILADEGEYSCEAENSVGAVSASGYLTVYDPPSI---------NLSPNSV-NVESGNVAR- 311
               DEGEYS EA N +G+    G L +  P  I            P  V  +++ +V   
Sbjct: 6105 SPDDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFVRQLKNKHVFNH 6164

Query: 312  ----FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
                F C   G P P + W   G +  I PG  R K  +     G   L I DT   D+ 
Sbjct: 6165 MPTIFDCLVVGHPAPEVEWFHNGKK--IVPG-GRIKIQSCG--GGSHALIILDTTLEDA- 6218

Query: 368  NTIVCSAVNYAGSSFVRGKLTVT 390
               V +A N  GS+     L VT
Sbjct: 6219 GEYVATAKNSHGSASSSAVLDVT 6241



 Score = 96.3 bits (229), Expect = 4e-18
 Identities = 125/542 (23%), Positives = 206/542 (38%), Gaps = 42/542 (7%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI--LPAGGLFFL 69
            P  ++ P +      +    +    G P P + WY     ++      +  +   G   +
Sbjct: 2269 PEFVQAPQNHETTLEESVKFSAIVTGKPMPNVTWYLNNKKLIQSEEVKVKYVHETGKTSI 2328

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVVL 127
            R     +  + G    EA N  G  ++  A L V    E  +F    + +Q  +G+ V  
Sbjct: 2329 RIQKPLMEHN-GTIRVEAENVSGKVQA-TAQLKVDKKTEVPKFTTNMDDRQVKEGEDVKF 2386

Query: 128  ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAA 186
                  G PEP+V W  NG+ +    +  +   DG + + I       AG   C A N  
Sbjct: 2387 TA-NVEGYPEPSVAWTLNGEPVSKHPNITVTDKDGEHTIEISAVTPEQAGELSCEATNPV 2445

Query: 187  GT--RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGN 243
            G+  R+  +A  K+   P      ED +   G       ++    P P + W +  G   
Sbjct: 2446 GSKKRDVQLAVKKVGDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKD-GVEI 2504

Query: 244  MPLGRVKVLD--DGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVYD-----PPS 294
               G  K+++  DGSL+L      L D+G  + +AE+  G    S  L V        P+
Sbjct: 2505 TSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAESEFGVAECSASLGVVKGRPMAKPA 2564

Query: 295  INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
                   +N+  G+        TG P P + W + G + +     + D   + A  +GV 
Sbjct: 2565 FQSDIAPINLTEGDTLECKLLITGDPTPFVKWYI-GTQLVC---ATEDTEISNA--NGVY 2618

Query: 355  VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPI-ITNGPSNQTLPIKS 413
             + I+     D    I C A N AG     G L V +    P P+       + T     
Sbjct: 2619 TMKIHGVTA-DMTGKIKCVAYNKAGEVSTEGPLKVVA----PIPVEFETSLCDATCREGD 2673

Query: 414  MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVAS 470
                    +  PEP+++WY  G+ L ++    + ++    T+ +KD+    SG   C A 
Sbjct: 2674 TLKLRAVLLGEPEPVVSWYVNGKKLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAI 2733

Query: 471  SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVT---DTSVTLSWSQN 527
            + +GK      LLV     P       ++V +  G  TK + H V    D   +L+W  N
Sbjct: 2734 NEYGKATSEATLLVLPRGEPPDFLEWLSNVRARTG--TK-VVHKVVFTGDPKPSLTWYIN 2790

Query: 528  NK 529
            NK
Sbjct: 2791 NK 2792



 Score = 92.7 bits (220), Expect = 6e-17
 Identities = 126/525 (24%), Positives = 200/525 (38%), Gaps = 43/525 (8%)

Query: 33   CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
            C   G P P + W       +  +H   L   G             D GVY  +  N +G
Sbjct: 669  CEVEGWPEPELVWLVDDQ-PLRPSHDFRLQYDGQTAKLEIRDAQPDDTGVYTVKIQNEFG 727

Query: 93   TARSRNATLHVAV------LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146
            +  S+ A L V        +  EF+   E  +  +G+ V  + +   G P P + W  NG
Sbjct: 728  SIESK-AELFVQADPDKNHVAPEFQATIEYVECDEGEEVRFKSVIT-GDPNPEIIWFING 785

Query: 147  QTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
            + L      +    DG   L I+D  +   G   C   N  G+  S    LK+ + P   
Sbjct: 786  KPLSESEKVKFISEDGICILTIKDVTRHFDGMVTCQGSNRLGSA-SCDGRLKVRVPPAPP 844

Query: 206  T--GP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR--VKVLD-DGSLRL 259
            T   P ED   Q  S+V F+  V G P P + +  +  G  +  G   V+++  DG  R+
Sbjct: 845  TFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTF--TLCGKELKNGEEGVEIVGHDGFYRI 902

Query: 260  D--NVIL-ADEGEYSCEAENSVGAVSASGYLTVYDP-------PSINLSPNSVNVESGNV 309
               N  +   +GE   +A+N  G   +   LTV          P+         V++G  
Sbjct: 903  SIPNTSMDKHDGEIVAKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEF 962

Query: 310  ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
            A F  T  G P P + W + G++  +  G    K  A      +T+      D      T
Sbjct: 963  AVFETTVRGNPNPEVTWFINGHK--MDQGSPGVKIEAHNHDHKLTI------DSAQYAGT 1014

Query: 370  IVCSAVNYAGSSFVRGKLTVTSDD-DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428
            ++C A N  G    + +L V + +  + PP       ++T  + +  VF       P+P 
Sbjct: 1015 VLCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPT 1074

Query: 429  IAWYFEGEALIQNHRRNVTN-DGT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485
            + WY +GE L Q+ R  +   DG+  + +K++   D+G    VA++  G       L V 
Sbjct: 1075 VTWYLKGEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQ 1134

Query: 486  -SPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
              P  P     R   ++   G       H       T  WS N +
Sbjct: 1135 KKPFAPEFD-LRPVSLTVEKGSEAVFSAHAFGIPLPTYEWSVNGR 1178



 Score = 92.7 bits (220), Expect = 6e-17
 Identities = 117/517 (22%), Positives = 201/517 (38%), Gaps = 69/517 (13%)

Query: 32   NCRAGGSPSPAIRWYKGGVLVVSDTHRSILP-AGGLFFLRATHGRVHSDAGVYWCEATNS 90
            N +  G P P ++W+  G+ +  D   ++   A G + L     R   D G   C A N 
Sbjct: 5191 NVKVRGLPKPTLQWFLNGIPIKFDDRITLDDMADGNYCLTIRDVR-EEDFGTLKCIAKNE 5249

Query: 91   YGTARS----RNATLHVAVLREEFRLEPE------SKQSAQGDTVVLECLPPRGSPEPNV 140
             GT  +    +    H    R++ R  P        ++   GD + +EC     +P   V
Sbjct: 5250 NGTDETVCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVD-ANPTAEV 5308

Query: 141  YWKKNGQTLLFDGDSRM-HLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
             W K+G+ +     + + + VDG   + I    ++D G Y C+A N  G  E+  AT ++
Sbjct: 5309 EWFKDGKKIEHTAHTEIRNTVDGACRIKIIPFEESDIGVYMCVAVNELGQAETQ-ATYQV 5367

Query: 199  HIKPYL-----------ITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
             I  ++           I  P ED     G  +   C+V   P   V+W +      +PL
Sbjct: 5368 EILEHVEEEKRREYAPKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDG----LPL 5423

Query: 247  GR-----VKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP------- 292
                   ++  +DG+  L +++    D G Y C A N+ G ++ S  + V  P       
Sbjct: 5424 RADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKE 5483

Query: 293  ---PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
               P        +  + G+     C  TG P P + W   G    +     R     +  
Sbjct: 5484 GEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQ---LLRNGPRTVIETSP- 5539

Query: 350  FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR---------GKLTVTSDDDRPPPII 400
             DG   LT+N++  +D      C A N  G +  +         GK      D+  PP  
Sbjct: 5540 -DGSCSLTVNESTMSDE-GIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKF 5597

Query: 401  TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-----LVLK 455
                S+ ++ + ++    C     P P + W  +G  LI++ R   +N+ +     L +K
Sbjct: 5598 ILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQLRIK 5657

Query: 456  DLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
            +    D GTY CVA++ +G       + +D  +   +
Sbjct: 5658 NATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGV 5694



 Score = 91.5 bits (217), Expect = 1e-16
 Identities = 110/474 (23%), Positives = 186/474 (39%), Gaps = 49/474 (10%)

Query: 38   SPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
            +P   ++WYK    +  ++H      G   +  A +     D   Y    +N+ G   S 
Sbjct: 4898 APVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSS 4957

Query: 98   NATLHVA--VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155
             A   V   VL+    L+    +  Q   V L+ +   G P+  + W KNGQ L  D D 
Sbjct: 4958 AALTVVKPNVLKIVDGLKDVDVEEPQ--PVELK-VKVEGIPKV-IKWYKNGQELKPDADG 5013

Query: 156  RM--HLVDGG--NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP--- 208
                   + G  +L I  ++++D G Y+ +  N  G   S      +H+K    + P   
Sbjct: 5014 FKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVYSGSV---VHVKSAKSSEPTSG 5070

Query: 209  -------EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA---GGGNMPLGRVKVLDDGSLR 258
                   +D   + G  +T QC + G+P P+V+W +        +    RV +    +LR
Sbjct: 5071 ANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLR 5130

Query: 259  LDNVILADEGEYSCEAENSVGAVSASGYLTVYD------PPSINLSPNSVNVESGNVARF 312
            + +   +D G+Y   A+N  G+ ++   +TV +       P   +   +     G+   F
Sbjct: 5131 IRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTGAALPGDKKEF 5190

Query: 313  TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
                 G P+PT+ W + G      P    D+     + DG   LTI D  + D   T+ C
Sbjct: 5191 NVKVRGLPKPTLQWFLNG-----IPIKFDDRITLDDMADGNYCLTIRDVREEDF-GTLKC 5244

Query: 373  SAVNYAGSSFV-------RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
             A N  G+           G    + DD R PP       ++ +P+       C     P
Sbjct: 5245 IAKNENGTDETVCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANP 5304

Query: 426  EPIIAWYFEGEALIQNHRRNVTN--DGTLVLK--DLDKSDSGTYTCVASSRHGK 475
               + W+ +G+ +       + N  DG   +K    ++SD G Y CVA +  G+
Sbjct: 5305 TAEVEWFKDGKKIEHTAHTEIRNTVDGACRIKIIPFEESDIGVYMCVAVNELGQ 5358



 Score = 90.2 bits (214), Expect = 3e-16
 Identities = 118/480 (24%), Positives = 194/480 (40%), Gaps = 35/480 (7%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P I+   +  TV + + AT N +  G P   ++WYK G  + +   +      G + L  
Sbjct: 4400 PEIVSGLIPTTVKQGETATFNVKVKG-PVKQVKWYKNGKEIPNAKAKD--NGDGSYSLEI 4456

Query: 72   THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
             + ++  D   Y    +N  G A S +A L V +         E  +  +G   VL+   
Sbjct: 4457 PNAQL-DDTADYKVVVSNDAGDADS-SAALTVKLPGIAIVKGLEDAEVPKGKKAVLQVET 4514

Query: 132  PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIARNAAG- 187
             +   E  + W KNG+ +    D      DG N   LVI DA   DA  Y+ +  +  G 
Sbjct: 4515 NKKPKE--IKWYKNGKEIT-PSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGN 4571

Query: 188  TRESAIA-TLKIHIK-PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG---GG 242
            T +S+ A T+K+  K P +I G ED V   GS +  +    G P   V W ++     G 
Sbjct: 4572 TADSSCALTVKLPAKEPKIIKGLEDQVVSIGSPIKLEIETSGSP-KTVKWYKNGKELPGA 4630

Query: 243  NMPLGRVKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP- 299
                 +++ +DD    L + + ++ D G+Y  E  N  G+ ++SG +TV +P    L P 
Sbjct: 4631 AAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITV-EPKITFLKPL 4689

Query: 300  NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
               ++  G  A F+     +P   + W   G    I P     ++      D    L I 
Sbjct: 4690 KDQSITEGENAEFSVETNTKPR-IVKWYKNGQE--IKP---NSRFIIEQKTDTKYQLVIK 4743

Query: 360  DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419
            +  ++D+ +T      N AG +    +LTV         I+  G  +Q +   +  VF  
Sbjct: 4744 NAVRDDA-DTYKIVLENTAGEAESSAQLTVKKAKAGLCKIV-KGLEDQVVAKGAKMVFEV 4801

Query: 420  TAICTPEPIIAWYFEGEALIQNHRRNVTN-DGT---LVLKDLDKSDSGTYTCVASSRHGK 475
                 PE  + W  +   +       +   D T   L++   D  D+G YT    +  GK
Sbjct: 4802 KIQGEPED-VRWLRDANVISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGK 4860



 Score = 88.2 bits (209), Expect = 1e-15
 Identities = 79/284 (27%), Positives = 116/284 (40%), Gaps = 10/284 (3%)

Query: 30   TLNCRA--GGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEA 87
            TL C+    G P+P ++WY G  LV +     I  A G++ ++  HG      G   C A
Sbjct: 2579 TLECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMK-IHGVTADMTGKIKCVA 2637

Query: 88   TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
             N  G   +      VA +  EF          +GDT+ L  +   G PEP V W  NG+
Sbjct: 2638 YNKAGEVSTEGPLKVVAPIPVEFETSLCDATCREGDTLKLRAV-LLGEPEPVVSWYVNGK 2696

Query: 148  TLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAG--TRESAIATLKIHIKPYL 204
             L    + ++H   G   + I+D     +G+  C A N  G  T E+ +  L     P  
Sbjct: 2697 KLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINEYGKATSEATLLVLPRGEPPDF 2756

Query: 205  ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSAGGGNMPLGRVKVLDDGSLRLDNVI 263
            +    +V A+TG+ V  +    GDP P + W   +    N  L  +   D  S    N  
Sbjct: 2757 LEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDKTSTLTINSF 2816

Query: 264  LAD--EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
              D   GE  C+AEN  G VS +  +  Y     + S +    E
Sbjct: 2817 NPDVHVGEIICKAENDAGEVSCTANMITYTSDMFSESESEAQAE 2860



 Score = 86.6 bits (205), Expect = 4e-15
 Identities = 98/460 (21%), Positives = 167/460 (36%), Gaps = 28/460 (6%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            E P       D  V   +         G P P++ W   G  V    + ++    G   +
Sbjct: 2365 EVPKFTTNMDDRQVKEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHPNITVTDKDGEHTI 2424

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE--FRLEPESKQSAQGDTVVL 127
              +       AG   CEATN  G+ + R+  L V  + +   F    E +   +G+  ++
Sbjct: 2425 EIS-AVTPEQAGELSCEATNPVGS-KKRDVQLAVKKVGDAPTFAKNLEDRLITEGELTLM 2482

Query: 128  ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ--DARQTDAGRYQCIARNA 185
            +       P+P + W K+G  +  DG  ++   + G+L +     +  D GR    A + 
Sbjct: 2483 DAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAESE 2542

Query: 186  AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSV--TFQCR--VGGDPLPDVLW----RR 237
             G  E + +   +  +P      +  +A    +   T +C+  + GDP P V W    + 
Sbjct: 2543 FGVAECSASLGVVKGRPMAKPAFQSDIAPINLTEGDTLECKLLITGDPTPFVKWYIGTQL 2602

Query: 238  SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
                 +  +     +   ++++  V     G+  C A N  G VS  G L V  P  +  
Sbjct: 2603 VCATEDTEISNANGVY--TMKIHGVTADMTGKIKCVAYNKAGEVSTEGPLKVVAPIPVEF 2660

Query: 298  SPN--SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
              +        G+  +      G PEP + W V G +          K H+     G   
Sbjct: 2661 ETSLCDATCREGDTLKLRAVLLGEPEPVVSWYVNGKK---LEESQNIKIHSEK---GTYT 2714

Query: 356  LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
            +TI D    D    +VC A+N  G +     L V    +  PP      SN      +  
Sbjct: 2715 VTIKDITC-DYSGQVVCEAINEYGKATSEATLLVLPRGE--PPDFLEWLSNVRARTGTKV 2771

Query: 416  VFPCTAICTPEPIIAWYFEGEALIQNHRRN-VTNDGTLVL 454
            V        P+P + WY   + ++ +     VT+D T  L
Sbjct: 2772 VHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDKTSTL 2811



 Score = 86.2 bits (204), Expect = 5e-15
 Identities = 80/296 (27%), Positives = 130/296 (43%), Gaps = 31/296 (10%)

Query: 17   QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAG-GLFFLRATHG 74
            +PL+V     +   L     G+P P + W+K    + + ++H      G G   L     
Sbjct: 3489 RPLEVR--EQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQA 3546

Query: 75   RVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
            R   D GVY C+ATN  G A++  N  +   +    F    +  +  QG    L  +   
Sbjct: 3547 R-GEDVGVYTCKATNEAGEAKTTANMAVQEEIEAPLFVQGLKPYEVEQGKPAEL-VVRVE 3604

Query: 134  GSPEPNVYWKKNGQTLLFDGDSRMHLVD--GGN----LVIQDARQTDAGRYQCIARNAAG 187
            G PEP V W K+G  +  D     H+++  G N    LVI+D    D G+Y C A N AG
Sbjct: 3605 GKPEPEVKWFKDGVPIAIDNQ---HVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAG 3661

Query: 188  TRESAIATLKI-----------HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
             ++  +  LKI            +KP  I   ++  A  G +V  +C+V  +  P + + 
Sbjct: 3662 -KDETVGELKIPKYSFEKQTAEEVKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFF 3720

Query: 237  RSAGGGNMPLG-RVKVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTV 289
            ++     +    +++VL+DG+++L   N    D G Y CEA N  G  + +  L +
Sbjct: 3721 KNDQPVEIGQHMQLEVLEDGNIKLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKI 3776



 Score = 81.0 bits (191), Expect = 2e-13
 Identities = 123/534 (23%), Positives = 198/534 (37%), Gaps = 37/534 (6%)

Query: 11   APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
            AP   ++   + V   + A   C+  G+  P ++W+K G  +  D               
Sbjct: 4017 APGFFKELSAIQVKETETAKFECKVSGT-KPDVKWFKDGTPLKEDKRVHFESTDDGTQRL 4075

Query: 71   ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
                    D G Y  E +N  G A S+     V     + +         QG  ++L  +
Sbjct: 4076 VIEDSKTDDQGNYRIEVSNDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQGTKILLS-V 4134

Query: 131  PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCI-ARNAAG 187
               G P+  V W K  +T+     +++  V      L I+ A  +D G Y+ + + ++  
Sbjct: 4135 EVEGKPK-TVKWYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFS 4193

Query: 188  TRESAIATL-----KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
               SA  T+     KI + P    G  D     G+ +  +  + G P  DV W ++  G 
Sbjct: 4194 VESSATVTVTKAAEKISL-PSFKKGLADQSVPKGTPLVLEVEIEGKP-KDVKWYKN--GD 4249

Query: 243  NMPLGRVKVLDDGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
             +  G+V+ L +G  RL   +    D GEYS  A N  G + +   + V   P I     
Sbjct: 4250 EIKDGKVEDLGNGKYRLTIPDFQEKDVGEYSVTAANEAGEIESKAKVNVSAKPEIVSGLV 4309

Query: 301  SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
               V+ G  A F     G P   + W   G    I    ++D        DG   L I +
Sbjct: 4310 PTTVKQGETATFNVKVKG-PVKGVKWYKNGKE--IPDAKTKDN------GDGSYSLEIPN 4360

Query: 361  TDKNDSRNTIVCSAVNYAGSSFVRGKLTV-TSDD--DRPPPIITNGPSNQTLPIKSMAVF 417
                D+ +  V  + N AG +     LTV  +DD  D+  P I +G    T+     A F
Sbjct: 4361 AQVEDAADYKVVVS-NDAGDADSSAALTVKLADDGKDKVKPEIVSGLIPTTVKQGETATF 4419

Query: 418  PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG--TLVLKDLDKSDSGTYTCVASSRHGK 475
                +  P   + WY  G+  I N +     DG  +L + +    D+  Y  V S+  G 
Sbjct: 4420 N-VKVKGPVKQVKWYKNGKE-IPNAKAKDNGDGSYSLEIPNAQLDDTADYKVVVSNDAGD 4477

Query: 476  YVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
               S AL V     P I   +  + + +P      +          + W +N K
Sbjct: 4478 ADSSAALTVKL---PGIAIVKGLEDAEVPKGKKAVLQVETNKKPKEIKWYKNGK 4528



 Score = 80.6 bits (190), Expect = 2e-13
 Identities = 102/403 (25%), Positives = 167/403 (41%), Gaps = 33/403 (8%)

Query: 9    GEAPYIIEQPLDVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPA-GGL 66
            G+AP   +   D  +   +   ++ +     P P I W K GV + SD H  I+    G 
Sbjct: 2460 GDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGS 2519

Query: 67   FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA----VLREEFRLEPESKQSAQG 122
              L     ++  D G    +A + +G A   +A+L V     + +  F+ +       +G
Sbjct: 2520 LKLSILQTKLE-DKGRITIKAESEFGVAEC-SASLGVVKGRPMAKPAFQSDIAPINLTEG 2577

Query: 123  DTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQC 180
            DT  LEC L   G P P V W    Q +    D+ +   +G   + I        G+ +C
Sbjct: 2578 DT--LECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMKIHGVTADMTGKIKC 2635

Query: 181  IARNAAGTRESAIATLKIHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
            +A N AG   S    LK+ + P  +   T   D   + G ++  +  + G+P P V W  
Sbjct: 2636 VAYNKAG-EVSTEGPLKV-VAPIPVEFETSLCDATCREGDTLKLRAVLLGEPEPVVSWYV 2693

Query: 238  SAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---D 291
            + G        +K+  +    ++ + ++     G+  CEA N  G  ++   L V    +
Sbjct: 2694 N-GKKLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINEYGKATSEATLLVLPRGE 2752

Query: 292  PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
            PP      ++V   +G         TG P+P++ W +  N+ I+    + D Y  T V D
Sbjct: 2753 PPDFLEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYIN-NKEIL----NSDLY--TIVTD 2805

Query: 352  GVT-VLTINDTDKNDSRNTIVCSAVNYAGS-SFVRGKLTVTSD 392
              T  LTIN  + +     I+C A N AG  S     +T TSD
Sbjct: 2806 DKTSTLTINSFNPDVHVGEIICKAENDAGEVSCTANMITYTSD 2848



 Score = 75.8 bits (178), Expect = 7e-12
 Identities = 99/334 (29%), Positives = 140/334 (41%), Gaps = 50/334 (14%)

Query: 3    DDYVTSGEAPYIIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTH-RSI 60
            D  +  G+AP     PL +  A+     T  C   G+P P+I+W K G+ + SD   +  
Sbjct: 5916 DSSIREGKAPGFTT-PLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKME 5974

Query: 61   LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR-------EEFRLE 113
              A G   L  +     S+ G + C ATN +GTA S  A L +   R        E   E
Sbjct: 5975 AAADGTQRLILSDVTFLSE-GYFRCVATNEHGTA-STKAELVIEGDRTIGSRPLPEVNGE 6032

Query: 114  PES----------KQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV--- 160
            PE             S     VV   +   G P P V W K+GQ ++ DG     ++   
Sbjct: 6033 PEECKPRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTD 6092

Query: 161  DGG--NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG---------PE 209
            + G  +LVI +A   D G Y   A N  G+ ++   +L I I+P  I           P 
Sbjct: 6093 ERGIHHLVIVNASPDDEGEYSLEATNKLGSAKTE-GSLNI-IRPRHIADADERGGMPFPP 6150

Query: 210  DVVAQTGSS-------VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG----SLR 258
              V Q  +          F C V G P P+V W  + G   +P GR+K+   G    +L 
Sbjct: 6151 GFVRQLKNKHVFNHMPTIFDCLVVGHPAPEVEWFHN-GKKIVPGGRIKIQSCGGGSHALI 6209

Query: 259  LDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
            + +  L D GEY   A+NS G+ S+S  L V  P
Sbjct: 6210 ILDTTLEDAGEYVATAKNSHGSASSSAVLDVTVP 6243



 Score = 75.4 bits (177), Expect = 9e-12
 Identities = 74/289 (25%), Positives = 114/289 (39%), Gaps = 23/289 (7%)

Query: 217 SSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DG--SLRLDNVILADEGEYSCE 273
           SS     +V G PLPD+ W +     +         D DG  ++ +D V + D G Y+C 
Sbjct: 563 SSAKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCM 622

Query: 274 AENSVGAVSASGYLTVYD------PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327
           A N  G  S S +  V        PP+          + G+V  F C   G PEP + W 
Sbjct: 623 ATNEYGQASTSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWL 682

Query: 328 VEGNRTIIFPGMSRDKYHATAVFDGVTV-LTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
           V+           R  +     +DG T  L I D   +D+         N  GS   + +
Sbjct: 683 VDDQPL-------RPSHDFRLQYDGQTAKLEIRDAQPDDT-GVYTVKIQNEFGSIESKAE 734

Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT--PEPIIAWYFEGEALIQNHR- 443
           L V +D D+         + + +           ++ T  P P I W+  G+ L ++ + 
Sbjct: 735 LFVQADPDKNHVAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKV 794

Query: 444 RNVTNDG--TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
           + ++ DG   L +KD+ +   G  TC  S+R G     G L V  P  P
Sbjct: 795 KFISEDGICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPAP 843



 Score = 74.5 bits (175), Expect = 2e-11
 Identities = 119/491 (24%), Positives = 192/491 (39%), Gaps = 40/491 (8%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL--PAGGLFFL 69
            P II+   D  V+   P  L     GSP   ++WYK G  +     ++I         ++
Sbjct: 4588 PKIIKGLEDQVVSIGSPIKLEIETSGSPK-TVKWYKNGKELPGAAAKTIKIQKIDDNKYV 4646

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS-AQGDTVVLE 128
                  V  D G Y  E  N  G+A   N++  + V  +   L+P   QS  +G+    E
Sbjct: 4647 LEIPSSVVEDTGDYKVEVANEAGSA---NSSGKITVEPKITFLKPLKDQSITEGENA--E 4701

Query: 129  CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN----LVIQDARQTDAGRYQCIARN 184
                  +    V W KNGQ +    +SR  +    +    LVI++A + DA  Y+ +  N
Sbjct: 4702 FSVETNTKPRIVKWYKNGQEI--KPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLEN 4759

Query: 185  AAGTRESAIATLKIHIKPYL---ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
             AG  ES+        K  L   + G ED V   G+ + F+ ++ G+P  DV W R A  
Sbjct: 4760 TAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKIQGEP-EDVRWLRDANV 4818

Query: 242  GNMPLGRV-KVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
             +     + + +DD + RL   +  L D GEY+ E  N  G   +     V + P I   
Sbjct: 4819 ISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGKAKSDAKGEVDEKPEIVRG 4878

Query: 299  PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
              ++ +  G+   F    +  P   + W    N   I P        A  +      L I
Sbjct: 4879 LENIEIPEGDDDVFKVEVSA-PVRQVKW--YKNDQEIKP---NSHLEAKKIGPKKYELAI 4932

Query: 359  NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
            N    +D  +  V  + N AG       LTV   +      I +G  +  +         
Sbjct: 4933 NRAQLDDGADYKVVLS-NAAGDCDSSAALTVVKPNVLK---IVDGLKDVDVEEPQPVELK 4988

Query: 419  CTAICTPEPIIAWYFEGEAL------IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
                  P+ +I WY  G+ L       +   +  + + +L +    KSD G Y  V  + 
Sbjct: 4989 VKVEGIPK-VIKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGND 5047

Query: 473  HGKYVWSGALL 483
             G+ V+SG+++
Sbjct: 5048 KGE-VYSGSVV 5057



 Score = 72.5 bits (170), Expect = 6e-11
 Identities = 87/393 (22%), Positives = 159/393 (40%), Gaps = 30/393 (7%)

Query: 105  VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN 164
            V+  +F  + +  ++ +G + V EC+ P  +      W K+G+ +      R+    G  
Sbjct: 2884 VMAPKFITKIKDTKAKKGHSAVFECVVP-DTKGVCCKWLKDGKEIELIARIRVQTRTGPE 2942

Query: 165  ------LVIQDARQTDAGRYQCIARNAAG--TRESAIATLKIHIK------PYLITGPED 210
                  LV+ +    DAG+Y CI  N AG  T E+ +  ++   K      P  I   +D
Sbjct: 2943 GHITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKKAPEFIVALQD 3002

Query: 211  VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGE 269
               +T   V  +C+V G+P P V W             V+ ++    + + +  L+ +G+
Sbjct: 3003 KTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVEGVERVTITSSELSHQGK 3062

Query: 270  YSCEAENSVGAVSASGYLTVY-DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328
            Y+C AEN+ G      +LTV  + P       +  +  G     +C+  G P+P + +  
Sbjct: 3063 YTCIAENTEGTSKTEAFLTVQGEAPVFTKELQNKELSIGEKLVLSCSVKGSPQPHVDFYS 3122

Query: 329  EGNRTIIFPGMSRDKYHATAVFDGVT--VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
                T +   ++     A       T   + I+   K D   +    A N  G++    K
Sbjct: 3123 FSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDI-VSYKAIATNSIGTATSTSK 3181

Query: 387  LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ--NH-- 442
            +T   +     P+   G    ++  K         +    P + W+ + + + +  NH  
Sbjct: 3182 ITTKVE----APVFEQGLKKTSVKEKEEIKME-VKVGGSAPDVEWFKDDKPVSEDGNHEM 3236

Query: 443  RRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
            ++N  T   TLV+K    +D+G YT  AS+  G
Sbjct: 3237 KKNPETGVFTLVVKQAATTDAGKYTAKASNPAG 3269



 Score = 72.5 bits (170), Expect = 6e-11
 Identities = 119/493 (24%), Positives = 193/493 (39%), Gaps = 42/493 (8%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P I+   +  TV + + AT N +  G P   ++WYK G  +     +      G + L  
Sbjct: 4302 PEIVSGLVPTTVKQGETATFNVKVKG-PVKGVKWYKNGKEIPDAKTKD--NGDGSYSLEI 4358

Query: 72   THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSA------QGDT 124
             + +V  DA  Y    +N  G A S +A L V +  + + +++PE           QG+T
Sbjct: 4359 PNAQVE-DAADYKVVVSNDAGDADS-SAALTVKLADDGKDKVKPEIVSGLIPTTVKQGET 4416

Query: 125  VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
                 +  +G P   V W KNG+ +  +  ++ +     +L I +A+  D   Y+ +  N
Sbjct: 4417 ATFN-VKVKG-PVKQVKWYKNGKEIP-NAKAKDNGDGSYSLEIPNAQLDDTADYKVVVSN 4473

Query: 185  AAGTRESAIA-TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
             AG  +S+ A T+K+     ++ G ED     G     Q      P  ++ W ++ G   
Sbjct: 4474 DAGDADSSAALTVKLP-GIAIVKGLEDAEVPKGKKAVLQVETNKKP-KEIKWYKN-GKEI 4530

Query: 244  MPLGRVKVLDDGSLRLDNVILA----DEGEYSCEAENSVG-AVSASGYLTVYDP---PSI 295
             P  + +   DG  +   VI      D  EY     +  G    +S  LTV  P   P I
Sbjct: 4531 TPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVKLPAKEPKI 4590

Query: 296  NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
                    V  G+  +     +G P+ T+ W   G      PG +        + D   V
Sbjct: 4591 IKGLEDQVVSIGSPIKLEIETSGSPK-TVKWYKNGKE---LPGAAAKTIKIQKIDDNKYV 4646

Query: 356  LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
            L I  +   D+ +  V    N AGS+   GK+TV      P         +Q++     A
Sbjct: 4647 LEIPSSVVEDTGDYKV-EVANEAGSANSSGKITV-----EPKITFLKPLKDQSITEGENA 4700

Query: 416  VFPCTAICTPEPIIAWYFEGEALIQNHR----RNVTNDGTLVLKDLDKSDSGTYTCVASS 471
             F       P  I+ WY  G+ +  N R    +       LV+K+  + D+ TY  V  +
Sbjct: 4701 EFSVETNTKPR-IVKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLEN 4759

Query: 472  RHGKYVWSGALLV 484
              G+   S  L V
Sbjct: 4760 TAGEAESSAQLTV 4772



 Score = 64.5 bits (150), Expect = 2e-08
 Identities = 54/207 (26%), Positives = 90/207 (43%), Gaps = 15/207 (7%)

Query: 115  ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG---QTLLFDGDSRMHLVDGGN--LVIQD 169
            E +  A+ DT+ +  L   G P+P++ WK  G    T       +++   G    L I  
Sbjct: 6417 EKRYCAENDTLTI-VLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITG 6475

Query: 170  ARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP 229
              + + G+YQC A+N  G  +  I  + +  +P  I    +    +   +    RV G+P
Sbjct: 6476 FSKENVGQYQCFAKNDYGDAQQNIM-VDLATRPNFIQPLVNKTFSSAQPMRMDVRVDGEP 6534

Query: 230  LPDVLWRRSAGGGNMPLGRVKVLDDG----SLRLDNVILADEGEYSCEAENSVGAVSASG 285
             P++ W +      +   R+K + DG    SL +++ +  D G YSC A N  G  + S 
Sbjct: 6535 FPELKWMKE-WRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSC 6593

Query: 286  YLTVY---DPPSINLSPNSVNVESGNV 309
             +TV    D   + L    V +ES  V
Sbjct: 6594 TVTVEAEGDYNDVELPRRRVTIESRRV 6620



 Score = 64.1 bits (149), Expect = 2e-08
 Identities = 94/423 (22%), Positives = 157/423 (37%), Gaps = 33/423 (7%)

Query: 8    SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
            S  AP  ++   D TV   + A       G+P+P + W+  G  +   +    + A    
Sbjct: 942  SRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFINGHKMDQGSPGVKIEAHNHD 1001

Query: 68   FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPE-------SKQSA 120
                     +  AG   C A N+ G   ++     + VL  E + +P         K   
Sbjct: 1002 HKLTIDSAQY--AGTVLCRAENAVGRFETK---ARLVVLAPEKQKKPPKFVEILVDKTET 1056

Query: 121  QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQ 179
              +TVV E +   G P+P V W   G+ L       +   DG   + I++ +  DAG  +
Sbjct: 1057 VDNTVVFE-VRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIR 1115

Query: 180  CIARNAAGTRESAIATLKIHIKPY---LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
             +A N+ G+ E+  A L +  KP+       P  +  + GS   F     G PLP   W 
Sbjct: 1116 AVATNSEGSDETK-AKLTVQKKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWS 1174

Query: 237  RSA-----GGGNMPLGRVKVLDDGS--LRLDNVILADEGEY---SCEAENSVGAVSASGY 286
             +      G     + R +   DG+  L +D      E  +   S  AEN++GA      
Sbjct: 1175 VNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISVVAENTLGAEETGAQ 1234

Query: 287  LTVYDPPSINLSPNSVNVESGNVARFTC--TATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
            LT+ +P   ++     ++ S  V +          PE T   ++E + T      +    
Sbjct: 1235 LTI-EPKKESVVVEKQDLSSSEVQKEIAQQVKEASPEATTTITMETSLTST-KTTTMSTT 1292

Query: 345  HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404
              T+   GVTV T  +++   +   I   +      S    K+ V S  D    +    P
Sbjct: 1293 EVTSTVGGVTVET-KESESESATTVIGGGSGGVTEGSISVSKIEVVSKTDSQTDVREGTP 1351

Query: 405  SNQ 407
              +
Sbjct: 1352 KRR 1354



 Score = 61.7 bits (143), Expect = 1e-07
 Identities = 66/257 (25%), Positives = 93/257 (36%), Gaps = 16/257 (6%)

Query: 277  SVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF 336
            +VG  ++S   T    P       S  V     A   C   G P P + W+ EG      
Sbjct: 3801 TVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEV--- 3857

Query: 337  PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD--- 393
              MS  +  A    DG   LT ++  + D+     C A N  GS++  G + VT +    
Sbjct: 3858 -EMSA-RVRAEHKDDGTLTLTFDNVTQADA-GEYRCEAENEYGSAWTEGPIIVTLEGAPK 3914

Query: 394  -DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN--DG 450
             D   P          + +   AV        P+P + WY  GE L  + R  + N  DG
Sbjct: 3915 IDGEAPDFLQPVKPAVVTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDG 3974

Query: 451  T--LVLKDLDKSDSGTYTCVASSRHGKYVWSG-ALLVDSPINPNIHFFRAADVSSLPGPP 507
            T  L + +    D   Y C AS+  G  VWS   L V  P      FF+      +    
Sbjct: 3975 TQRLTVTNAKLDDMDEYRCEASNEFGD-VWSDVTLTVKEPAQVAPGFFKELSAIQVKETE 4033

Query: 508  TKPITHNVTDTSVTLSW 524
            T      V+ T   + W
Sbjct: 4034 TAKFECKVSGTKPDVKW 4050



 Score = 60.9 bits (141), Expect = 2e-07
 Identities = 54/215 (25%), Positives = 86/215 (40%), Gaps = 25/215 (11%)

Query: 388  TVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT 447
            T  +DD    PI T    +  L     A+F C    +P P + W F+G+ L  N R  + 
Sbjct: 7518 TKKNDDGTFAPIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIE 7577

Query: 448  NDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLP 504
             D     L+L      D G Y C A + +G    S  L+             + +  S P
Sbjct: 7578 QDNNVARLILNHAAPYDLGEYVCTAINEYGTDKSSCRLI-------------SGETPSRP 7624

Query: 505  GPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIA 564
            G P   ++   +DT + + W      G + + G    +  R  ++G N   +   W+ ++
Sbjct: 7625 GRPEAELS---SDTEIFIQWEAPE--GPTYLEGITYRLEYR--VAGPND--HGDPWITVS 7675

Query: 565  RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
             ++     +VK L P   Y F V  +N  GL  PS
Sbjct: 7676 EKIDDESVIVKHLSPLGIYQFRVTAQNGFGLGLPS 7710



 Score = 60.5 bits (140), Expect = 3e-07
 Identities = 89/376 (23%), Positives = 149/376 (39%), Gaps = 27/376 (7%)

Query: 169  DARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228
            D     +G    +A NAAG+ E+    LK+   P     PE         VT    V  D
Sbjct: 1944 DTTMFGSGTVSVVASNAAGSVETK-TELKVLETPKETKKPEFTDKLRDMEVTKGDTVQMD 2002

Query: 229  --PLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA---DEGEYSCEAENSVGAVSA 283
               L   L++    G  +  G+  V         ++I+    D G+ + EA N VG+  +
Sbjct: 2003 VIALHSPLYKWYQNGNLLEDGKNGVTIKNEENKSSLIIPNAQDSGKITVEASNEVGSSES 2062

Query: 284  SGYLTVYDP---PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340
            S  LTV  P   P +   P SV ++    A F  T +G P PT+ W++  N  I+     
Sbjct: 2063 SAQLTVNPPSTTPIVVDGPKSVTIKETETAEFKATISGFPAPTVKWTI--NEKIV----E 2116

Query: 341  RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP--PP 398
              +   T   + V  L I++  K +   T+  +A N AG    +  L V  +   P    
Sbjct: 2117 ESRTITTIKTEDVYTLKISNA-KIEQTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKS 2175

Query: 399  IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN--DGT--LVL 454
             +T+  +++  P++           +P   ++W   G+ L ++    V +  DGT  + +
Sbjct: 2176 QLTDKVADEGEPLRWNLELDGP---SPGTEVSWLLNGQPLTKSDTVQVVDHGDGTYHVTI 2232

Query: 455  KDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHN 514
             +     SGT T  A +  G+   S  + V+   N    F +A          +   +  
Sbjct: 2233 AEAKPEMSGTLTAKAKNAAGECETSAKVTVNGG-NKKPEFVQAPQNHETTLEESVKFSAI 2291

Query: 515  VTDTSV-TLSWSQNNK 529
            VT   +  ++W  NNK
Sbjct: 2292 VTGKPMPNVTWYLNNK 2307



 Score = 51.6 bits (118), Expect = 1e-04
 Identities = 47/171 (27%), Positives = 75/171 (43%), Gaps = 12/171 (7%)

Query: 24   ARHQPATLNCRAGGSPSPAIRW-YKG-GVLVVSDTHR-SILPAGGLFFLRATHGRVHSDA 80
            A +   T+     G P P I+W ++G  +   S T +  +   GG     A  G    + 
Sbjct: 6422 AENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSKENV 6481

Query: 81   GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
            G Y C A N YG A+ +N  + +A  R  F ++P   ++      +   +   G P P +
Sbjct: 6482 GQYQCFAKNDYGDAQ-QNIMVDLAT-RPNF-IQPLVNKTFSSAQPMRMDVRVDGEPFPEL 6538

Query: 141  YWKKNGQTLLFDGDSRMHLVDGG----NLVIQDARQTDAGRYQCIARNAAG 187
             W K  + ++    SR+  V  G    +L+I D    D+G Y C+A N AG
Sbjct: 6539 KWMKEWRPIV--ESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAG 6587



 Score = 48.4 bits (110), Expect = 0.001
 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 1/86 (1%)

Query: 11   APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
            AP    +  DV + ++QPA   C    SP+P + W   G ++ S+   +I     +  L 
Sbjct: 7527 APIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIEQDNNVARLI 7586

Query: 71   ATHGRVHSDAGVYWCEATNSYGTARS 96
              H   + D G Y C A N YGT +S
Sbjct: 7587 LNHAAPY-DLGEYVCTAINEYGTDKS 7611



 Score = 39.9 bits (89), Expect = 0.41
 Identities = 21/83 (25%), Positives = 36/83 (43%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P  I+  ++ T +  QP  ++ R  G P P ++W K    +V  +    +  G       
Sbjct: 6507 PNFIQPLVNKTFSSAQPMRMDVRVDGEPFPELKWMKEWRPIVESSRIKFVQDGPYLCSLI 6566

Query: 72   THGRVHSDAGVYWCEATNSYGTA 94
             +  +  D+G+Y C A N  G A
Sbjct: 6567 INDPMWRDSGIYSCVAVNDAGQA 6589


>UniRef50_Q13308 Cluster: Tyrosine-protein kinase-like 7 precursor;
           n=29; Tetrapoda|Rep: Tyrosine-protein kinase-like 7
           precursor - Homo sapiens (Human)
          Length = 1070

 Score =  146 bits (354), Expect = 3e-33
 Identities = 127/486 (26%), Positives = 209/486 (43%), Gaps = 37/486 (7%)

Query: 14  IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT------HRSILPAGGLF 67
           ++  P DV VAR++ A  +C+    P P+++W       +++        R+ + A G  
Sbjct: 227 VVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSL 286

Query: 68  FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
            L     R   +AG+Y C      G      ATLH+A + +    EP    +   + V  
Sbjct: 287 LLTQVRPR---NAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVT- 342

Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
            CLPP+G PEP+V+W+  G  L   G  R++   G  LV+ +  ++DAG Y C A N AG
Sbjct: 343 -CLPPKGLPEPSVWWEHAGVRLPTHG--RVYQ-KGHELVLANIAESDAGVYTCHAANLAG 398

Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
            R   +  + +   P  +  P+D   + G      C     P P V+W R+    +    
Sbjct: 399 QRRQDV-NITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISED-S 456

Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN-VES 306
           R +V  +G+LR+++V + D   Y C +    G++ A   + V +       P     +E 
Sbjct: 457 RFEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEF 516

Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
              A   C+ATGR +PT+ W           G S  ++    V D    L      ++D+
Sbjct: 517 DKEATVPCSATGREKPTIKWERAD-------GSSLPEW----VTDNAGTLHFARVTRDDA 565

Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
            N    ++    G      +LTV              P   T+     A+  C A   P+
Sbjct: 566 GNYTCIASNGPQGQIRAHVQLTVAVFIT-----FKVEPERTTVYQGHTALLQCEAQGDPK 620

Query: 427 PIIAWYFEGEALIQNH---RRNVTNDGTLVLKDLDKSDSGTYTCVA-SSRHGKYVWSGAL 482
           P+I W  +   L       R ++  +G+LV+ D+   DSG YTC+A +S + K+  +   
Sbjct: 621 PLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLY 680

Query: 483 LVDSPI 488
           +VD P+
Sbjct: 681 VVDKPV 686



 Score =  112 bits (270), Expect = 5e-23
 Identities = 106/373 (28%), Positives = 155/373 (41%), Gaps = 28/373 (7%)

Query: 37  GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
           G P P++ W   GV +   TH  +   G    L        SDAGVY C A N  G  R 
Sbjct: 348 GLPEPSVWWEHAGVRL--PTHGRVYQKGHELVLANI---AESDAGVYTCHAANLAGQRR- 401

Query: 97  RNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSR 156
           ++  + VA +    + +P+  Q  +G    L+CL  + +P+P V W +N   +L   DSR
Sbjct: 402 QDVNITVATVPSWLK-KPQDSQLEEGKPGYLDCLT-QATPKPTVVWYRN--QMLISEDSR 457

Query: 157 MHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE-DVVAQT 215
             +   G L I      D   Y+C++   AG+ E A A +++  K      P+     + 
Sbjct: 458 FEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIE-AQARVQVLEKLKFTPPPQPQQCMEF 516

Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGEYSCEA 274
               T  C   G   P + W R A G ++P     V D+ G+L    V   D G Y+C A
Sbjct: 517 DKEATVPCSATGREKPTIKWER-ADGSSLPEW---VTDNAGTLHFARVTRDDAGNYTCIA 572

Query: 275 ENSV-GAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRT 333
            N   G + A   LTV    +  + P    V  G+ A   C A G P+P + W  +G   
Sbjct: 573 SNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQW--KGKDR 630

Query: 334 IIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
           I+ P     + H   +F   + L I+D    DS     C A N          L V    
Sbjct: 631 ILDPTKLGPRMH---IFQNGS-LVIHDVAPEDS-GRYTCIAGNSCNIKHTEAPLYVV--- 682

Query: 394 DRPPPIITNGPSN 406
           D+P P  + GP +
Sbjct: 683 DKPVPEESEGPGS 695



 Score =  108 bits (260), Expect = 8e-22
 Identities = 127/474 (26%), Positives = 191/474 (40%), Gaps = 41/474 (8%)

Query: 12  PYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFL 69
           P +++ P  +  +      TL C   G P P  +W++ G  L    ++ ++        L
Sbjct: 128 PVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTL 187

Query: 70  RATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFR---LEPESKQSAQGDTV 125
           R   G  HS  G+Y C A +++G A  S+N TL +A   E F    L P+    A+ +  
Sbjct: 188 RPA-GPEHS--GLYSCCAHSAFGQACSSQNFTLSIA--DESFARVVLAPQDVVVARYEEA 242

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL-----VDGGNLVIQDARQTDAGRYQC 180
           +  C      P P++ W    +T + +     HL        G+L++   R  +AG Y+C
Sbjct: 243 MFHC-QFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRC 301

Query: 181 IARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
           I +   G      ATL +  I+   +  P    A +   VT      G P P V W  + 
Sbjct: 302 IGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTC-LPPKGLPEPSVWWEHA- 359

Query: 240 GGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
            G  +P  GRV       L L N+  +D G Y+C A N  G       +TV   PS    
Sbjct: 360 -GVRLPTHGRV-YQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKK 417

Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
           P    +E G      C     P+PT+ W    N+ +I    S D      VF   T L I
Sbjct: 418 PQDSQLEEGKPGYLDCLTQATPKPTVVW--YRNQMLI----SEDS--RFEVFKNGT-LRI 468

Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
           N  +  D      C +   AGS   + ++ V       PP        Q +     A  P
Sbjct: 469 NSVEVYDG-TWYRCMSSTPAGSIEAQARVQVLEKLKFTPP----PQPQQCMEFDKEATVP 523

Query: 419 CTAICTPEPIIAW-YFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
           C+A    +P I W   +G +L +       N GTL    + + D+G YTC+AS+
Sbjct: 524 CSATGREKPTIKWERADGSSLPE---WVTDNAGTLHFARVTRDDAGNYTCIASN 574



 Score =  101 bits (243), Expect = 9e-20
 Identities = 126/479 (26%), Positives = 187/479 (39%), Gaps = 44/479 (9%)

Query: 15  IEQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
           I+QP      + + A L C    +P P  + W   G   V DT R       L F  A  
Sbjct: 35  IKQPSSQDALQGRRALLRCEVE-APGPVHVYWLLDGA-PVQDTERRFAQGSSLSF--AAV 90

Query: 74  GRVHSDAGVYWCEATNSYG--TARSRNATLHVAVLREE--FRLEPESKQSAQGDT-VVLE 128
            R+  D+G + C A +      ARS NA+ ++  +         P S+   Q  T V L 
Sbjct: 91  DRLQ-DSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 149

Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAA 186
           C    G P P   W ++G T L DG S  H V     NL ++ A    +G Y C A +A 
Sbjct: 150 CHID-GHPRPTYQWFRDG-TPLSDGQSN-HTVSSKERNLTLRPAGPEHSGLYSCCAHSAF 206

Query: 187 GTR-ESAIATLKIHIKPY--LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSA 239
           G    S   TL I  + +  ++  P+DVV        F C+    P P + W        
Sbjct: 207 GQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPI 266

Query: 240 GGGNMP--LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSIN 296
              + P  L R  V  +GSL L  V   + G Y C  +   G  +     L + +   + 
Sbjct: 267 TNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMP 326

Query: 297 LSPNSVNVESGNVARFTCTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
           L    V   +G+  R TC    G PEP+++W   G R    P   R       V+     
Sbjct: 327 LFEPRV-FTAGSEERVTCLPPKGLPEPSVWWEHAGVR---LPTHGR-------VYQKGHE 375

Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
           L + +  ++D+     C A N AG       +TV +      P     P +  L      
Sbjct: 376 LVLANIAESDA-GVYTCHAANLAGQRRQDVNITVAT-----VPSWLKKPQDSQLEEGKPG 429

Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
              C    TP+P + WY     + ++ R  V  +GTL +  ++  D   Y C++S+  G
Sbjct: 430 YLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCMSSTPAG 488



 Score = 92.3 bits (219), Expect = 7e-17
 Identities = 78/296 (26%), Positives = 119/296 (40%), Gaps = 18/296 (6%)

Query: 3   DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
           D  +T    P  +++P D  +   +P  L+C    +P P + WY+  +L+  D+   +  
Sbjct: 403 DVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFK 462

Query: 63  AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQ 121
            G L   R     V+ D   Y C ++   G   S  A   V VL + +F   P+ +Q  +
Sbjct: 463 NGTL---RINSVEVY-DGTWYRCMSSTPAG---SIEAQARVQVLEKLKFTPPPQPQQCME 515

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV--DGGNLVIQDARQTDAGRYQ 179
            D          G  +P + W++       DG S    V  + G L      + DAG Y 
Sbjct: 516 FDKEATVPCSATGREKPTIKWERA------DGSSLPEWVTDNAGTLHFARVTRDDAGNYT 569

Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RS 238
           CIA N    +  A   L + +       PE      G +   QC   GDP P + W+ + 
Sbjct: 570 CIASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKD 629

Query: 239 AGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
                  LG R+ +  +GSL + +V   D G Y+C A NS         L V D P
Sbjct: 630 RILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKP 685



 Score = 83.0 bits (196), Expect = 4e-14
 Identities = 97/384 (25%), Positives = 151/384 (39%), Gaps = 36/384 (9%)

Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
           F  +P S+ + QG   +L C      P  +VYW  +G  +    D+      G +L    
Sbjct: 34  FIKQPSSQDALQGRRALLRCEVEAPGPV-HVYWLLDGAPVQ---DTERRFAQGSSLSFAA 89

Query: 170 A-RQTDAGRYQCIARNAAGTRESAIATLKIHIK-----PYLITGP-EDVVAQTGSSVTFQ 222
             R  D+G +QC+AR+     E+  A    +IK     P ++  P  +   Q  + VT +
Sbjct: 90  VDRLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 149

Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVG-A 280
           C + G P P   W R     +       V   + +L L        G YSC A ++ G A
Sbjct: 150 CHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQA 209

Query: 281 VSASGY-LTVYDPP--SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337
            S+  + L++ D     + L+P  V V     A F C  + +P P++ W  E    I   
Sbjct: 210 CSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNR 269

Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV-RGKLTVTSDDDRP 396
                   AT   +G  +LT     +  +     C      G   +    L +   +D P
Sbjct: 270 SRPPHLRRATVFANGSLLLT---QVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMP 326

Query: 397 ---PPIITNGPSNQT--LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT 451
              P + T G   +   LP K +          PEP + W   G  L   H R       
Sbjct: 327 LFEPRVFTAGSEERVTCLPPKGL----------PEPSVWWEHAGVRL-PTHGRVYQKGHE 375

Query: 452 LVLKDLDKSDSGTYTCVASSRHGK 475
           LVL ++ +SD+G YTC A++  G+
Sbjct: 376 LVLANIAESDAGVYTCHAANLAGQ 399


>UniRef50_O00533 Cluster: Neural cell adhesion molecule L1-like
           protein precursor; n=25; Euteleostomi|Rep: Neural cell
           adhesion molecule L1-like protein precursor - Homo
           sapiens (Human)
          Length = 1208

 Score =  146 bits (354), Expect = 3e-33
 Identities = 120/485 (24%), Positives = 200/485 (41%), Gaps = 34/485 (7%)

Query: 10  EAPYIIEQP-LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
           + P II+Q  + V     +   + C A G+P P   W K G       HR I       F
Sbjct: 33  QVPTIIKQSKVQVAFPFDEYFQIECEAKGNPEPTFSWTKDGNPFYFTDHRIIPSNNSGTF 92

Query: 69  LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
                G +    G Y C A+N  G A S      V  + +  + + +  +  +GD +VL 
Sbjct: 93  RIPNEGHISHFQGKYRCFASNKLGIAMSEEIEFIVPSVPKFPKEKIDPLEVEEGDPIVLP 152

Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIARNAAG 187
           C PP+G P  ++YW  N +    + D R+++   G+L   +  + D+   Y C A     
Sbjct: 153 CNPPKGLPPLHIYWM-NIELEHIEQDERVYMSQKGDLYFANVEEKDSRNDYCCFAAFPRL 211

Query: 188 TRESAIATLKIHI---------KPYLITGPEDVVAQT------GSSVTFQCRVGGDPLPD 232
                   +K+ +         KP L+  P +  +++      G  +  +C   G P P 
Sbjct: 212 RTIVQKMPMKLTVNSSNSIKQRKPKLLLPPTESGSESSITILKGEILLLECFAEGLPTPQ 271

Query: 233 VLWRRSAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
           V W +   GG++P GR    + G +L+++NV   D+G Y C A N +G  +   ++ V +
Sbjct: 272 VDWNKI--GGDLPKGREAKENYGKTLKIENVSYQDKGNYRCTASNFLGTATHDFHVIVEE 329

Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
           PP     P S    +G+     C A G P+PT+ W V G+     P      +    VF 
Sbjct: 330 PPRWTKKPQSAVYSTGSNGILLCEAEGEPQPTIKWRVNGSPVDNHP------FAGDVVFP 383

Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
               ++  +   N +     C A N  G+      + V    D  P I T    N    +
Sbjct: 384 --REISFTNLQPNHTA-VYQCEASNVHGTILANANIDVV---DVRPLIQTKDGENYATVV 437

Query: 412 KSMAVFPCTAICTPEPIIAWY-FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470
              A   C    +PE +++W   E    ++  R ++  +GTL +    + D+G+Y+C   
Sbjct: 438 GYSAFLHCEFFASPEAVVSWQKVEEVKPLEGRRYHIYENGTLQINRTTEEDAGSYSCWVE 497

Query: 471 SRHGK 475
           +  GK
Sbjct: 498 NAIGK 502



 Score = 84.2 bits (199), Expect = 2e-14
 Identities = 83/301 (27%), Positives = 124/301 (41%), Gaps = 20/301 (6%)

Query: 3   DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
           D +V   E P   ++P     +      L C A G P P I+W   G  V  D H     
Sbjct: 322 DFHVIVEEPPRWTKKPQSAVYSTGSNGILLCEAEGEPQPTIKWRVNGSPV--DNHPF--- 376

Query: 63  AGGLFFLR--ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL-EPESKQS 119
           AG + F R  +      +   VY CEA+N +GT  + NA + V  +R   +  + E+  +
Sbjct: 377 AGDVVFPREISFTNLQPNHTAVYQCEASNVHGTILA-NANIDVVDVRPLIQTKDGENYAT 435

Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179
             G +  L C     SPE  V W+K  +    +G  R H+ + G L I    + DAG Y 
Sbjct: 436 VVGYSAFLHC-EFFASPEAVVSWQKVEEVKPLEG-RRYHIYENGTLQINRTTEEDAGSYS 493

Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP-LPDVL---W 235
           C   NA G + +  A L I     L   P++        +   C    D  L   L   W
Sbjct: 494 CWVENAIG-KTAVTANLDIRNATKLRVSPKNPRIPKLHMLELHCESKCDSHLKHSLKLSW 552

Query: 236 RRSAGG---GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
            +            GR+ ++D  +L + NV L D+G Y C A  ++ + +    +TV D 
Sbjct: 553 SKDGEAFEINGTEDGRI-IIDGANLTISNVTLEDQGIYCCSAHTALDSAADITQVTVLDV 611

Query: 293 P 293
           P
Sbjct: 612 P 612



 Score = 82.6 bits (195), Expect = 6e-14
 Identities = 69/299 (23%), Positives = 119/299 (39%), Gaps = 17/299 (5%)

Query: 21  VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
           +T+ + +   L C A G P+P + W K G     D  +                  + D 
Sbjct: 250 ITILKGEILLLECFAEGLPTPQVDWNKIG----GDLPKGREAKENYGKTLKIENVSYQDK 305

Query: 81  GVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
           G Y C A+N  GTA       HV V     +  +P+S   + G   +L C    G P+P 
Sbjct: 306 GNYRCTASNFLGTATH---DFHVIVEEPPRWTKKPQSAVYSTGSNGILLC-EAEGEPQPT 361

Query: 140 VYWKKNGQTL---LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
           + W+ NG  +    F GD    +V    +   + +      YQC A N  GT  +     
Sbjct: 362 IKWRVNGSPVDNHPFAGD----VVFPREISFTNLQPNHTAVYQCEASNVHGTILANANID 417

Query: 197 KIHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
            + ++P + T   E+     G S    C     P   V W++      +   R  + ++G
Sbjct: 418 VVDVRPLIQTKDGENYATVVGYSAFLHCEFFASPEAVVSWQKVEEVKPLEGRRYHIYENG 477

Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
           +L+++     D G YSC  EN++G  + +  L + +   + +SP +  +   ++    C
Sbjct: 478 TLQINRTTEEDAGSYSCWVENAIGKTAVTANLDIRNATKLRVSPKNPRIPKLHMLELHC 536



 Score = 46.0 bits (104), Expect = 0.006
 Identities = 65/283 (22%), Positives = 107/283 (37%), Gaps = 25/283 (8%)

Query: 222 QCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNV--ILADEGEYSCEAENSV 278
           +C   G+P P   W +          R+   ++ G+ R+ N   I   +G+Y C A N +
Sbjct: 56  ECEAKGNPEPTFSWTKDGNPFYFTDHRIIPSNNSGTFRIPNEGHISHFQGKYRCFASNKL 115

Query: 279 G-AVSASGYLTVYDPPSINLSP-NSVNVESGNVARFTCTAT-GRPEPTMFWSVEGNRTII 335
           G A+S      V   P       + + VE G+     C    G P   ++W       I 
Sbjct: 116 GIAMSEEIEFIVPSVPKFPKEKIDPLEVEEGDPIVLPCNPPKGLPPLHIYWM-----NIE 170

Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG---KLTVTSD 392
              + +D+            L   + ++ DSRN   C A      + V+    KLTV S 
Sbjct: 171 LEHIEQDE---RVYMSQKGDLYFANVEEKDSRNDYCCFAAFPRLRTIVQKMPMKLTVNSS 227

Query: 393 DD----RP----PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR 444
           +     +P    PP  +   S+ T+    + +  C A   P P + W   G  L +    
Sbjct: 228 NSIKQRKPKLLLPPTESGSESSITILKGEILLLECFAEGLPTPQVDWNKIGGDLPKGREA 287

Query: 445 NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
                 TL ++++   D G Y C AS+  G       ++V+ P
Sbjct: 288 KENYGKTLKIENVSYQDKGNYRCTASNFLGTATHDFHVIVEEP 330



 Score = 39.9 bits (89), Expect = 0.41
 Identities = 44/168 (26%), Positives = 64/168 (38%), Gaps = 11/168 (6%)

Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSN-SRVAQTLDDVPDGPPINIEMFILNTTTVHLKW 752
           I  L  + +Y+F +I   +    +PS  S   +T    PD  P NI +       + +KW
Sbjct: 673 ILPLAPFVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAPDRNPQNIRVQASQPKEMIIKW 732

Query: 753 SPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAA 812
            P +   QNG   G    V W   P    +     TV   T  +MT       Y V++ A
Sbjct: 733 EPLKSMEQNG--PGLEYRVTW--KPQGAPVEWEEETVTNHTLRVMTPAVY-APYDVKVQA 787

Query: 813 ETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETW 860
              +G GP  Q V     +   G D     P+   V ++    V  TW
Sbjct: 788 INQLGSGPDPQSV-----TLYSGEDYPDTAPVIHGVDVINSTLVKVTW 830


>UniRef50_Q4SR20 Cluster: Chromosome 11 SCAF14528, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 11 SCAF14528, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 786

 Score =  145 bits (352), Expect = 6e-33
 Identities = 139/510 (27%), Positives = 214/510 (41%), Gaps = 60/510 (11%)

Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT 173
           PES  +A+   V LEC    G+P P + W++    + F    +M       L I + +Q 
Sbjct: 83  PESVPAAKESAVKLECFA-LGNPVPEISWRRTSG-IPFPSKVKMKN-SNAVLEIPNFQQE 139

Query: 174 DAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233
           DAG Y+C+A N  G + +A   L  H KP+ +    D      +++ ++C+  G P P  
Sbjct: 140 DAGTYECVAENRRG-KNAARGRLSFHAKPHWLQTMADTALSIEANLFWECKANGKPKPSY 198

Query: 234 LWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-DP 292
            W ++ G      GR+++ D+G+L +  + L+D G Y C AEN  G + +S  L V   P
Sbjct: 199 SWLKN-GEQVAAEGRIQI-DNGALSIAVLNLSDSGMYQCVAENKHGIIYSSAQLMVLASP 256

Query: 293 PSINLSPNS--VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
           P+ + SP    +   SG+     C     P     W  +GN   I P   R       + 
Sbjct: 257 PNFSKSPLKALLKARSGSEVTLECKPEAWPPAISLWK-KGNE--ILPRTERIN-----LL 308

Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
              T+   N T ++    T  C A N  G++   GKL +T      P  IT  P+N  + 
Sbjct: 309 PNGTIKIANATRQDAGSYT--CIAKNQFGTASTTGKLLITE-----PTRITMRPTNTEII 361

Query: 411 IKSMAVFPCTAICTP--EPIIAWYFEGEAL-IQ---NHRRNVTND--GTLVLKDLDKSDS 462
           +   AV PC     P  +   +W F G+ +  Q   NH   V     G L+++++  S  
Sbjct: 362 VGESAVLPCQIAFDPALDVSFSWAFNGQLIDFQRDGNHFERVGGSVSGDLMIRNIQLSHG 421

Query: 463 GTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTL 522
           G Y C+  +       S  L+V  P                PGPP K     +TD++  L
Sbjct: 422 GKYVCLIDTDVESLSTSAILVVKGP----------------PGPPDKVTVEEITDSTAQL 465

Query: 523 SWSQNNKIGSSSILGYQVEVFSRETL---SGNNTPRNSRGWVVIARRVHQTHYVVKSLIP 579
           SW+     G S I GY ++  +  T+   + +  P    G ++ A         V  L  
Sbjct: 466 SWTPGRDNG-SPITGYIIQARTPFTVGWQAVDTVPEVINGNMLTA--------TVVGLNA 516

Query: 580 GITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
            + Y F V   N+ GL  PSP S      D
Sbjct: 517 WVEYEFRVVARNAVGLGEPSPASAKTRTED 546



 Score =  107 bits (257), Expect = 2e-21
 Identities = 88/335 (26%), Positives = 142/335 (42%), Gaps = 19/335 (5%)

Query: 2   SDDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSI 60
           SD  +   E    +  P  V  A+     L C A G+P P I W +  G+   S      
Sbjct: 67  SDGVMGEYEPKIEVHFPESVPAAKESAVKLECFALGNPVPEISWRRTSGIPFPSKVKMKN 126

Query: 61  LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA 120
             A     L   + +   DAG Y C A N  G   +R   L         +   ++  S 
Sbjct: 127 SNA----VLEIPNFQ-QEDAGTYECVAENRRGKNAARGR-LSFHAKPHWLQTMADTALSI 180

Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
           + + +  EC    G P+P+  W KNG+ +  +G  +   +D G L I     +D+G YQC
Sbjct: 181 EAN-LFWEC-KANGKPKPSYSWLKNGEQVAAEGRIQ---IDNGALSIAVLNLSDSGMYQC 235

Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVV--AQTGSSVTFQCRVGGDPLPDVLWRRS 238
           +A N  G   S+   + +   P     P   +  A++GS VT +C+    P    LW++ 
Sbjct: 236 VAENKHGIIYSSAQLMVLASPPNFSKSPLKALLKARSGSEVTLECKPEAWPPAISLWKK- 294

Query: 239 AGGGNMP-LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
            G   +P   R+ +L +G++++ N    D G Y+C A+N  G  S +G L + +P  I +
Sbjct: 295 -GNEILPRTERINLLPNGTIKIANATRQDAGSYTCIAKNQFGTASTTGKLLITEPTRITM 353

Query: 298 SPNSVNVESGNVARFTCTATGRP--EPTMFWSVEG 330
            P +  +  G  A   C     P  + +  W+  G
Sbjct: 354 RPTNTEIIVGESAVLPCQIAFDPALDVSFSWAFNG 388



 Score =  102 bits (245), Expect = 5e-20
 Identities = 89/363 (24%), Positives = 156/363 (42%), Gaps = 37/363 (10%)

Query: 142 WKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
           W  N        DSR  +  + G+L I    ++D G Y C+  N     +   +   + +
Sbjct: 6   WIFNEYPHFVQQDSRRFISQETGSLYIAKVERSDVGNYTCVVNNTVTGDKVLSSPTPLVL 65

Query: 201 KPYLITG----------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRV 249
           +   + G          PE V A   S+V  +C   G+P+P++ WRR++G   +P   +V
Sbjct: 66  RSDGVMGEYEPKIEVHFPESVPAAKESAVKLECFALGNPVPEISWRRTSG---IPFPSKV 122

Query: 250 KVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNVES 306
           K+ +  + L + N    D G Y C AEN  G  +A G L+ +  P     ++  ++++E+
Sbjct: 123 KMKNSNAVLEIPNFQQEDAGTYECVAENRRGKNAARGRLSFHAKPHWLQTMADTALSIEA 182

Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
                + C A G+P+P+  W   G +      +  D    +     + VL ++D+     
Sbjct: 183 NLF--WECKANGKPKPSYSWLKNGEQVAAEGRIQIDNGALS-----IAVLNLSDSGMYQ- 234

Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA--VFPCTAICT 424
                C A N  G  +   +L V +     PP  +  P    L  +S +     C     
Sbjct: 235 -----CVAENKHGIIYSSAQLMVLAS----PPNFSKSPLKALLKARSGSEVTLECKPEAW 285

Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
           P  I  W    E L +  R N+  +GT+ + +  + D+G+YTC+A ++ G    +G LL+
Sbjct: 286 PPAISLWKKGNEILPRTERINLLPNGTIKIANATRQDAGSYTCIAKNQFGTASTTGKLLI 345

Query: 485 DSP 487
             P
Sbjct: 346 TEP 348



 Score =  100 bits (239), Expect = 3e-19
 Identities = 87/304 (28%), Positives = 128/304 (42%), Gaps = 24/304 (7%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P+ ++   D  ++        C+A G P P+  W K G  V ++    I    G   +  
Sbjct: 167 PHWLQTMADTALSIEANLFWECKANGKPKPSYSWLKNGEQVAAEGRIQI--DNGALSIAV 224

Query: 72  THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTVVLEC 129
            +    SD+G+Y C A N +G   S +A L V      F   P     ++  G  V LEC
Sbjct: 225 LN---LSDSGMYQCVAENKHGIIYS-SAQLMVLASPPNFSKSPLKALLKARSGSEVTLEC 280

Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
            P    P  ++ WKK  + L      R++L+  G + I +A + DAG Y CIA+N  GT 
Sbjct: 281 KPEAWPPAISL-WKKGNEIL--PRTERINLLPNGTIKIANATRQDAGSYTCIAKNQFGT- 336

Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-------- 241
            S    L I     +   P +     G S    C++  DP  DV +  +  G        
Sbjct: 337 ASTTGKLLITEPTRITMRPTNTEIIVGESAVLPCQIAFDPALDVSFSWAFNGQLIDFQRD 396

Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
           GN    RV     G L + N+ L+  G+Y C  +  V ++S S  L V  PP     P+ 
Sbjct: 397 GN-HFERVGGSVSGDLMIRNIQLSHGGKYVCLIDTDVESLSTSAILVVKGPPG---PPDK 452

Query: 302 VNVE 305
           V VE
Sbjct: 453 VTVE 456


>UniRef50_Q98902 Cluster: Neural cell adhesion molecule L1
           precursor; n=7; Clupeocephala|Rep: Neural cell adhesion
           molecule L1 precursor - Fugu rubripes (Japanese
           pufferfish) (Takifugu rubripes)
          Length = 1277

 Score =  145 bits (352), Expect = 6e-33
 Identities = 170/727 (23%), Positives = 289/727 (39%), Gaps = 92/727 (12%)

Query: 121 QGDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179
           +G T+ LEC+  +G P P V W +K+G+  + +      + D   L   +  ++D G YQ
Sbjct: 272 RGQTLELECIV-QGLPTPKVSWLRKDGE--MSESRISKDMFDR-RLQFTNISESDGGEYQ 327

Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
           C A N  G R     T+ +   PY    P   +   G +V   C+  G P P + W  + 
Sbjct: 328 CTAENVQG-RTFHTYTVTVEASPYWTNAPVSQLYAPGETVKLDCQADGIPSPTITWTVNG 386

Query: 240 G--GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSI- 295
                     R  + + GSL L +VI  D   Y C+A N  G + A+  + V + PP I 
Sbjct: 387 VPLSATSLEPRRSLTESGSLILKDVIFGDTAIYQCQASNKHGTILANTNVYVIELPPQIL 446

Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
             + N+     G  A   C   G P+P + W       ++      D         G+ +
Sbjct: 447 TENGNTYTFVEGQKALLECETFGSPKPKVTWESSSISLLL-----ADPRVNLLTNGGLEI 501

Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
             ++  D+      +  S ++      V  +  + S    PP  +   P          A
Sbjct: 502 ANVSHDDEGIYTCLVQGSNISVNAEVEVLNRTVILS----PPQALRLQPGKT-------A 550

Query: 416 VFPCTAICTPE---PIIAWYFEGEALIQNHR-RNVTNDGT-LVLKDLDKSDSGTYTCVAS 470
           +F C  +  P+   P++ W    + + ++H  +  T DG  L++ +++  D G YTC   
Sbjct: 551 IFTCLYVTDPKLSSPLLQWRKNDQKIFESHSDKKYTFDGPGLIISNVEPGDEGVYTCQII 610

Query: 471 SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530
           ++      S  L +                   P PP      N     VTL+W+  +  
Sbjct: 611 TKLDMVEASSTLTL----------------CDRPDPPVHLQVTNAKHRVVTLNWTPGDD- 653

Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590
            +S IL Y VE F  + +  N       GW  + R      +V   L P ++Y F V   
Sbjct: 654 NNSPILEYVVE-FEDQDMKEN-------GWEELKRVAADKKHVNLPLWPYMSYRFRVIAI 705

Query: 591 NSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIK 650
           N  G S PS +SD      D+         SN  + R+           E+T  D  T+ 
Sbjct: 706 NDQGKSDPSKLSDLYKTPADAPD-------SNPEDVRS-----------EST--DPDTLV 745

Query: 651 LMWEILNFYYLEG-----LFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEF 705
           + WE ++     G     L ++ R + +    +E  TI        F +T ++ ++ +E 
Sbjct: 746 ITWEEMDKRNFNGPDFKYLVMWRRVVGSGPDWHEEYTI-----APPFIVTDVQNFSAFEI 800

Query: 706 FLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIIT 765
            +    KK  G   +  +  + +DVP   P+N+ + + N+TT+ + WS  + +   G + 
Sbjct: 801 KVQAVNKKGLGPEPDPIIGYSGEDVPLEAPLNLGVLLENSTTIRVTWSAVDKETVRGHLL 860

Query: 766 GYNVVVNW-----LDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGP 820
           GY + + W           +++V + T  ++    I TNL     Y + I+A    G GP
Sbjct: 861 GYKIYLTWGHHRNSRAQEPENIVMVQTGANEEKKSI-TNLRPYCHYDLAISAFNSKGEGP 919

Query: 821 FSQKVYF 827
            S+K  F
Sbjct: 920 LSEKTSF 926



 Score =  144 bits (348), Expect = 2e-32
 Identities = 127/477 (26%), Positives = 193/477 (40%), Gaps = 32/477 (6%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGG---L 66
           P I  QP  VTV   +   + C A G+PSP   W K G      SD    +    G    
Sbjct: 51  PAITTQPESVTVFSVEDLVMRCEASGNPSPTFHWTKDGEEFDPSSDPEMKVTEEAGSSVF 110

Query: 67  FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
           + L  T   +    G Y C A+N  GTA S  A L +     + + +  ++++  G ++ 
Sbjct: 111 YTLSNTMDTLKQYQGKYICYASNELGTAVSNAAVLMIDAPPVQQKEKKVTEKAEAGHSIA 170

Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG----NLVIQDARQTDAGRYQCIA 182
           L C PP+ S +P ++W  N    +   D  M   DG     NL+ +D+R       Q +A
Sbjct: 171 LSCNPPQSSMQPIIHWMDNRLRHIRLSDRVMVGKDGNLYFANLLTEDSRNDYTCNIQYLA 230

Query: 183 RNAAGTRESAIATLKI------HIKPYLI--TGPEDVV-AQTGSSVTFQCRVGGDPLPDV 233
                 +E    T+        + +P ++  TG      A  G ++  +C V G P P V
Sbjct: 231 TRTILAKEPITLTVNPSNLVPRNRRPQMMRPTGSHSTYHALRGQTLELECIVQGLPTPKV 290

Query: 234 LWRRSAGGGNMPLGRV-KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
            W R    G M   R+ K + D  L+  N+  +D GEY C AEN  G    +  +TV   
Sbjct: 291 SWLRK--DGEMSESRISKDMFDRRLQFTNISESDGGEYQCTAENVQGRTFHTYTVTVEAS 348

Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
           P    +P S     G   +  C A G P PT+ W+V G      P +S            
Sbjct: 349 PYWTNAPVSQLYAPGETVKLDCQADGIPSPTITWTVNG-----VP-LSATSLEPRRSLTE 402

Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
              L + D    D+     C A N  G+      + V    + PP I+T   +  T    
Sbjct: 403 SGSLILKDVIFGDTA-IYQCQASNKHGTILANTNVYVI---ELPPQILTENGNTYTFVEG 458

Query: 413 SMAVFPCTAICTPEPIIAWYFEG-EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468
             A+  C    +P+P + W       L+ + R N+  +G L + ++   D G YTC+
Sbjct: 459 QKALLECETFGSPKPKVTWESSSISLLLADPRVNLLTNGGLEIANVSHDDEGIYTCL 515



 Score =  113 bits (272), Expect = 3e-23
 Identities = 86/296 (29%), Positives = 137/296 (46%), Gaps = 18/296 (6%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS---DTHRSILP 62
           VT   +PY    P+    A  +   L+C+A G PSP I W   GV + +   +  RS+  
Sbjct: 343 VTVEASPYWTNAPVSQLYAPGETVKLDCQADGIPSPTITWTVNGVPLSATSLEPRRSLTE 402

Query: 63  AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS-AQ 121
           +G L       G    D  +Y C+A+N +GT  + N  ++V  L  +   E  +  +  +
Sbjct: 403 SGSLILKDVIFG----DTAIYQCQASNKHGTILA-NTNVYVIELPPQILTENGNTYTFVE 457

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
           G   +LEC    GSP+P V W+ +  +LL   D R++L+  G L I +    D G Y C+
Sbjct: 458 GQKALLEC-ETFGSPKPKVTWESSSISLLL-ADPRVNLLTNGGLEIANVSHDDEGIYTCL 515

Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP---LPDVLWRRS 238
            +   G+  S  A +++  +  +++ P+ +  Q G +  F C    DP    P + WR++
Sbjct: 516 VQ---GSNISVNAEVEVLNRTVILSPPQALRLQPGKTAIFTCLYVTDPKLSSPLLQWRKN 572

Query: 239 AGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
                      K   DG  L + NV   DEG Y+C+    +  V AS  LT+ D P
Sbjct: 573 DQKIFESHSDKKYTFDGPGLIISNVEPGDEGVYTCQIITKLDMVEASSTLTLCDRP 628



 Score = 88.2 bits (209), Expect = 1e-15
 Identities = 99/392 (25%), Positives = 156/392 (39%), Gaps = 49/392 (12%)

Query: 113 EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVI---- 167
           +PES      + +V+ C    G+P P  +W K+G+      D  M + +  G+ V     
Sbjct: 56  QPESVTVFSVEDLVMRC-EASGNPSPTFHWTKDGEEFDPSSDPEMKVTEEAGSSVFYTLS 114

Query: 168 --QDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVV---AQTGSSVTFQ 222
              D  +   G+Y C A N  GT  S  A L I   P  +   E  V   A+ G S+   
Sbjct: 115 NTMDTLKQYQGKYICYASNELGTAVSNAAVLMIDAPP--VQQKEKKVTEKAEAGHSIALS 172

Query: 223 CRVGGDPL-PDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE-GEYSCEAEN-SVG 279
           C      + P + W  +         RV V  DG+L   N++  D   +Y+C  +  +  
Sbjct: 173 CNPPQSSMQPIIHWMDNRLRHIRLSDRVMVGKDGNLYFANLLTEDSRNDYTCNIQYLATR 232

Query: 280 AVSASGYLTVYDPPSINLSP--------------NSVNVESGNVARFTCTATGRPEPTMF 325
            + A   +T+   PS NL P              ++ +   G      C   G P P + 
Sbjct: 233 TILAKEPITLTVNPS-NLVPRNRRPQMMRPTGSHSTYHALRGQTLELECIVQGLPTPKVS 291

Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385
           W +  +  +    +S+D +     F       I+++D  + +    C+A N  G +F   
Sbjct: 292 W-LRKDGEMSESRISKDMFDRRLQFTN-----ISESDGGEYQ----CTAENVQGRTFHTY 341

Query: 386 KLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH--- 442
            +TV +      P  TN P +Q           C A   P P I W   G  L       
Sbjct: 342 TVTVEAS-----PYWTNAPVSQLYAPGETVKLDCQADGIPSPTITWTVNGVPLSATSLEP 396

Query: 443 RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
           RR++T  G+L+LKD+   D+  Y C AS++HG
Sbjct: 397 RRSLTESGSLILKDVIFGDTAIYQCQASNKHG 428



 Score = 66.9 bits (156), Expect = 3e-09
 Identities = 50/180 (27%), Positives = 75/180 (41%), Gaps = 13/180 (7%)

Query: 5   YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPA 63
           YV       + E     T    Q A L C   GSP P + W    + L+++D   ++L  
Sbjct: 437 YVIELPPQILTENGNTYTFVEGQKALLECETFGSPKPKVTWESSSISLLLADPRVNLLTN 496

Query: 64  GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
           GGL     +    H D G+Y C      G+  S NA + V + R      P++ +   G 
Sbjct: 497 GGLEIANVS----HDDEGIYTCLV---QGSNISVNAEVEV-LNRTVILSPPQALRLQPGK 548

Query: 124 TVVLECL---PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
           T +  CL    P+ S  P + W+KN Q +      + +  DG  L+I +    D G Y C
Sbjct: 549 TAIFTCLYVTDPKLS-SPLLQWRKNDQKIFESHSDKKYTFDGPGLIISNVEPGDEGVYTC 607



 Score = 55.2 bits (127), Expect = 1e-05
 Identities = 37/126 (29%), Positives = 58/126 (46%), Gaps = 4/126 (3%)

Query: 694  ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
            IT+LR Y  Y+  +  F  K EG  S      T + VP GPP++++M   + + + L W+
Sbjct: 896  ITNLRPYCHYDLAISAFNSKGEGPLSEKTSFMTPEGVP-GPPMSMQMTSPSESEITLHWT 954

Query: 754  PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAE 813
            PP     NGI+ GY++    +    N   V ++    + T L +  L     Y   + A 
Sbjct: 955  PP--SKPNGILLGYSLQYRKMQSDDNPLQV-VDIASPEITHLTLKGLDRHSHYQFLLMAR 1011

Query: 814  TIIGLG 819
            T  G G
Sbjct: 1012 TAAGKG 1017



 Score = 50.8 bits (116), Expect = 2e-04
 Identities = 78/354 (22%), Positives = 136/354 (38%), Gaps = 39/354 (11%)

Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG--RVKVLDD- 254
           + I P + T PE V   +   +  +C   G+P P   W +  G    P     +KV ++ 
Sbjct: 47  LKIPPAITTQPESVTVFSVEDLVMRCEASGNPSPTFHWTKD-GEEFDPSSDPEMKVTEEA 105

Query: 255 GS---LRLDN---VILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV--NVES 306
           GS     L N    +   +G+Y C A N +G   ++  + + D P +      V    E+
Sbjct: 106 GSSVFYTLSNTMDTLKQYQGKYICYASNELGTAVSNAAVLMIDAPPVQQKEKKVTEKAEA 165

Query: 307 GNVARFTCT-ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
           G+    +C       +P + W     R I               F    +LT       D
Sbjct: 166 GHSIALSCNPPQSSMQPIIHWMDNRLRHIRLSDRVMVGKDGNLYF--ANLLT------ED 217

Query: 366 SRNTIVCSAVNYAGSSFVRGK----LTVTSDD----DRPPPIITNGPSNQTL-PIKSMAV 416
           SRN   C+ + Y  +  +  K    LTV   +    +R P ++    S+ T   ++   +
Sbjct: 218 SRNDYTCN-IQYLATRTILAKEPITLTVNPSNLVPRNRRPQMMRPTGSHSTYHALRGQTL 276

Query: 417 -FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
              C     P P ++W  +   + ++       D  L   ++ +SD G Y C A +  G+
Sbjct: 277 ELECIVQGLPTPKVSWLRKDGEMSESRISKDMFDRRLQFTNISESDGGEYQCTAENVQGR 336

Query: 476 YVWSGALLVDSPINPNIHFFRAADVSSL--PGPPTKPITHNVTDTSVTLSWSQN 527
              +  + V++  +P   ++  A VS L  PG   K         S T++W+ N
Sbjct: 337 TFHTYTVTVEA--SP---YWTNAPVSQLYAPGETVKLDCQADGIPSPTITWTVN 385



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 32/105 (30%), Positives = 44/105 (41%), Gaps = 10/105 (9%)

Query: 393 DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL--IQNHRRNVTND- 449
           D + PP IT  P + T+      V  C A   P P   W  +GE      +    VT + 
Sbjct: 46  DLKIPPAITTQPESVTVFSVEDLVMRCEASGNPSPTFHWTKDGEEFDPSSDPEMKVTEEA 105

Query: 450 GTLVLKDLD------KSDSGTYTCVASSRHGKYVWSGA-LLVDSP 487
           G+ V   L       K   G Y C AS+  G  V + A L++D+P
Sbjct: 106 GSSVFYTLSNTMDTLKQYQGKYICYASNELGTAVSNAAVLMIDAP 150


>UniRef50_UPI0000E4A6A5 Cluster: PREDICTED: similar to heparan sulfate
            proteoglycan perlecan; n=4; Strongylocentrotus
            purpuratus|Rep: PREDICTED: similar to heparan sulfate
            proteoglycan perlecan - Strongylocentrotus purpuratus
          Length = 2331

 Score =  145 bits (351), Expect = 7e-33
 Identities = 126/476 (26%), Positives = 208/476 (43%), Gaps = 47/476 (9%)

Query: 15   IEQPL---DVTVARHQPATLNCRAGGSPSP-AIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
            +EQ L   ++ V   + A  +C + G+P+   I W +    + S    ++  + GL  + 
Sbjct: 1263 VEQELLLRELEVIEGETAVFSCTSPGTPAGYTITWRRVSQRMPS----TVSISNGLLTIP 1318

Query: 71   ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
                +    AG Y+C   N +G  +    TL+V VL     + P ++    G+ + + C 
Sbjct: 1319 QARSQY---AGQYYCIVGNEHGYQQDL-VTLYVLVL-PSLSISPTTQTVTAGEIIRISCF 1373

Query: 131  PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
               G+      W K G +L         +  GG L I  A  TDAG+Y+C+  N AG R+
Sbjct: 1374 A-EGTQPITCEWSKYGGSL-----PPTAIQSGGILQISPATATDAGQYRCVCSNTAGFRD 1427

Query: 191  SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250
            S + T+++ + P +   P       G SV F C+  G P P + W +  G     L    
Sbjct: 1428 SYM-TVRVQVIPTVTAIPARETRAIGGSVEFSCQATGTPPPQITWEKEDG----VLPAQH 1482

Query: 251  VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV--NVESGN 308
             + +G L L ++   DEG Y C A N  G+  A   L ++  P++ ++ N+    +  G 
Sbjct: 1483 RITNGVLSLISLRDGDEGRYVCTATNQAGSSKAYARLFLHAAPTVQITVNTTVHYIRVGE 1542

Query: 309  VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
               F C +TG P P + W+   +   I           + V  G   LTI     +D   
Sbjct: 1543 TTTFECLSTGDPTPVVTWTKVNSEMPI-----------SVVLQGAR-LTIPQVSLSDV-G 1589

Query: 369  TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428
               C+A N  GS   +  L V +      P +T  PS +T P+ S   F C A   P P 
Sbjct: 1590 FYRCTATNIVGSRTSQVFLYVQA-----APQLTVVPSTRTAPVGSTLEFSCLAGGFPTPE 1644

Query: 429  IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
            I W+ +   L  N++    ++G L + ++ ++D GTY C+A+++ G       L+V
Sbjct: 1645 ITWHKDDGDLPDNYQ---IDNGLLTITNVKEADEGTYVCIATNQGGSTEHRARLVV 1697



 Score =  131 bits (317), Expect = 1e-28
 Identities = 120/467 (25%), Positives = 201/467 (43%), Gaps = 40/467 (8%)

Query: 78   SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL---EPESKQSAQGDTVVLECLPPRG 134
            +DAG++   A+N +G   S  A + + V+ +  R+   +P++ +  +G+TV   C     
Sbjct: 698  NDAGIFIFTASNRFG---SGTAEVRLEVVGQAMRVVINDPQTVEVPEGETVQFVCRGISQ 754

Query: 135  SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194
            +P   + W ++  TL  +    M     G L I   R +DAG+Y C+  N   T + A A
Sbjct: 755  TPAYTIAWSRSDGTLPTNARDFM-----GILTIDTVRLSDAGQYVCMGSNQRDTAD-AYA 808

Query: 195  TLKIHI---KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
            TL +     +P +   P  +    G  V F+C   G+P P + W    GG    L     
Sbjct: 809  TLIVTSSVQEPTVRIEPRFIRITEGDRVEFRCIATGNPTPTLRWSGGQGG---VLNSEST 865

Query: 252  LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP--PSINLSPNSVNVESGNV 309
             ++G   +     +DE EY CEA NS G  +    L V     PS+ +SP S +V  G  
Sbjct: 866  FENGLFVIPKARASDEAEYFCEATNSAGMATIRTVLYVSPSRVPSVTISPASESVSEGER 925

Query: 310  ARFTCTATGRPEPTMFWS-VEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
              F C ATG P P   WS ++G+     P  +R++ +   V   VT          +   
Sbjct: 926  VIFYCQATGDPAPERTWSRIDGD----MPSSAREE-NGYLVISAVTY---------EVEG 971

Query: 369  TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428
               C+A N  GS +   ++T+++D  R P    + P+  T+   +  V  C     P P 
Sbjct: 972  VYRCTATNSHGSDYSDAQITISTDSRRSPTARID-PAEITVTQGATQVLRCLTTGVPTPT 1030

Query: 429  IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPI 488
            I W      L  N +     +G L + + D +D   Y+C A++  G    +  + ++   
Sbjct: 1031 ITWTRGSGPLSANQQ---ALNGVLRIINADVTDRDMYSCTATNIAGSSTATAYVEIERRE 1087

Query: 489  NPNIHFFRAADVSSLPGPPTKPITHNVTD-TSVTLSWSQNNKIGSSS 534
            +P I     +   ++ G   +     ++   + T+SWS+ N    SS
Sbjct: 1088 SPVIEILPYSTYIAIDGDNIQIQCRILSGIPTPTVSWSRANGAPLSS 1134



 Score =  128 bits (308), Expect = 1e-27
 Identities = 129/494 (26%), Positives = 209/494 (42%), Gaps = 55/494 (11%)

Query: 7    TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWY--KGGVLVVSDTHRSILPAG 64
            +S + P +  +P  + +         C A G+P+P +RW   +GGVL    T  +     
Sbjct: 814  SSVQEPTVRIEPRFIRITEGDRVEFRCIATGNPTPTLRWSGGQGGVLNSESTFEN----- 868

Query: 65   GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR-EEFRLEPESKQSAQGD 123
            GLF +        SD   Y+CEATNS G A  R   L+V+  R     + P S+  ++G+
Sbjct: 869  GLFVIPKARA---SDEAEYFCEATNSAGMATIR-TVLYVSPSRVPSVTISPASESVSEGE 924

Query: 124  TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCIA 182
             V+  C    G P P   W +       DGD       + G LVI        G Y+C A
Sbjct: 925  RVIFYC-QATGDPAPERTWSR------IDGDMPSSAREENGYLVISAVTYEVEGVYRCTA 977

Query: 183  RNAAGTRES-AIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
             N+ G+  S A  T+    +  P     P ++    G++   +C   G P P + W R +
Sbjct: 978  TNSHGSDYSDAQITISTDSRRSPTARIDPAEITVTQGATQVLRCLTTGVPTPTITWTRGS 1037

Query: 240  GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV--YDPPSINL 297
            G    PL   +   +G LR+ N  + D   YSC A N  G+ +A+ Y+ +   + P I +
Sbjct: 1038 G----PLSANQQALNGVLRIINADVTDRDMYSCTATNIAGSSTATAYVEIERRESPVIEI 1093

Query: 298  SPNS--VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
             P S  + ++  N+       +G P PT+ WS      +           ++   D + V
Sbjct: 1094 LPYSTYIAIDGDNIQIQCRILSGIPTPTVSWSRANGAPL-----------SSNTNDEMGV 1142

Query: 356  LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT-LPIKSM 414
            LTI      +++   +C+  N AGS+     + V     +  P I+  P+N     +   
Sbjct: 1143 LTIMGVTA-ENQGAYICTGTNSAGSATATATIRV-----QGLPQISITPTNPAEFRVGET 1196

Query: 415  AVFPCTAICTPEPIIAW-YFEGEALIQNHRR--NVTNDGTLV--LKDLDKSDSGTYTCVA 469
            AV  C A   P P + W     E + Q      N+  + + +  ++ +  +D+G+Y C A
Sbjct: 1197 AVLECVATGEPLPTVQWMVMNNERVYQPIAAAFNMEEESSAMHYIQSVSMNDAGSYMCRA 1256

Query: 470  SSRHGKYVWSGALL 483
             +  G YV    LL
Sbjct: 1257 ENGAG-YVEQELLL 1269



 Score =  127 bits (306), Expect = 2e-27
 Identities = 128/479 (26%), Positives = 193/479 (40%), Gaps = 52/479 (10%)

Query: 5    YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
            YV+    P +   P   +V+  +     C+A G P+P   W +    +  D   S     
Sbjct: 902  YVSPSRVPSVTISPASESVSEGERVIFYCQATGDPAPERTWSR----IDGDMPSSAREEN 957

Query: 65   GLFFLRATHGRVHSDAGVYWCEATNSYGTARS-RNATLHVAVLREEF-RLEPESKQSAQG 122
            G   + A    V    GVY C ATNS+G+  S    T+     R    R++P      QG
Sbjct: 958  GYLVISAVTYEVE---GVYRCTATNSHGSDYSDAQITISTDSRRSPTARIDPAEITVTQG 1014

Query: 123  DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
             T VL CL   G P P + W +    L     S       G L I +A  TD   Y C A
Sbjct: 1015 ATQVLRCLTT-GVPTPTITWTRGSGPL-----SANQQALNGVLRIINADVTDRDMYSCTA 1068

Query: 183  RNAAGTRES-AIATLKIHIKPYLITGPEDV-VAQTGSSVTFQCRV-GGDPLPDVLWRRSA 239
             N AG+  + A   ++    P +   P    +A  G ++  QCR+  G P P V W R+ 
Sbjct: 1069 TNIAGSSTATAYVEIERRESPVIEILPYSTYIAIDGDNIQIQCRILSGIPTPTVSWSRAN 1128

Query: 240  GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
            G    PL      + G L +  V   ++G Y C   NS G+ +A+  + V   P I+++P
Sbjct: 1129 GA---PLSSNTNDEMGVLTIMGVTAENQGAYICTGTNSAGSATATATIRVQGLPQISITP 1185

Query: 300  -NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP-GMSRDKYHATAVFDGVTVLT 357
             N      G  A   C ATG P PT+ W V  N  +  P   + +    ++    +  ++
Sbjct: 1186 TNPAEFRVGETAVLECVATGEPLPTVQWMVMNNERVYQPIAAAFNMEEESSAMHYIQSVS 1245

Query: 358  INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
            +ND        + +C A N  G+ +V  +L +     R   +I              AVF
Sbjct: 1246 MNDA------GSYMCRAEN--GAGYVEQELLL-----RELEVIEG----------ETAVF 1282

Query: 418  PCTAICTPEP-IIAWYFEGEALIQNHRRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHG 474
             CT+  TP    I W      + Q     V+ ++G L +       +G Y C+  + HG
Sbjct: 1283 SCTSPGTPAGYTITW----RRVSQRMPSTVSISNGLLTIPQARSQYAGQYYCIVGNEHG 1337



 Score =  122 bits (294), Expect = 6e-26
 Identities = 110/380 (28%), Positives = 163/380 (42%), Gaps = 35/380 (9%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P +   P   TV   +   ++C A G+      W K G         + + +GG+  +  
Sbjct: 1351 PSLSISPTTQTVTAGEIIRISCFAEGTQPITCEWSKYG----GSLPPTAIQSGGILQISP 1406

Query: 72   THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
                  +DAG Y C  +N+ G  R    T+ V V+     + P  +  A G +V   C  
Sbjct: 1407 ATA---TDAGQYRCVCSNTAGF-RDSYMTVRVQVIPTVTAI-PARETRAIGGSVEFSC-Q 1460

Query: 132  PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
              G+P P + W+K    L        H +  G L +   R  D GRY C A N AG+ + 
Sbjct: 1461 ATGTPPPQITWEKEDGVL-----PAQHRITNGVLSLISLRDGDEGRYVCTATNQAGSSK- 1514

Query: 192  AIATLKIHIKPYL-ITGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249
            A A L +H  P + IT    V   + G + TF+C   GDP P V W +      MP+   
Sbjct: 1515 AYARLFLHAAPTVQITVNTTVHYIRVGETTTFECLSTGDPTPVVTWTKV--NSEMPIS-- 1570

Query: 250  KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309
             VL    L +  V L+D G Y C A N VG+ ++  +L V   P + + P++     G+ 
Sbjct: 1571 VVLQGARLTIPQVSLSDVGFYRCTATNIVGSRTSQVFLYVQAAPQLTVVPSTRTAPVGST 1630

Query: 310  ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
              F+C A G P P + W  +        G   D Y    + +G  +LTI +  + D   T
Sbjct: 1631 LEFSCLAGGFPTPEITWHKD-------DGDLPDNYQ---IDNG--LLTITNVKEAD-EGT 1677

Query: 370  IVCSAVNYAGSSFVRGKLTV 389
             VC A N  GS+  R +L V
Sbjct: 1678 YVCIATNQGGSTEHRARLVV 1697



 Score =  116 bits (279), Expect = 4e-24
 Identities = 136/510 (26%), Positives = 207/510 (40%), Gaps = 65/510 (12%)

Query: 31   LNCRA-GGSPSPAIRWYKG-GVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
            + CR   G P+P + W +  G  + S+T+  +   G L  +  T      + G Y C  T
Sbjct: 1109 IQCRILSGIPTPTVSWSRANGAPLSSNTNDEM---GVLTIMGVTA----ENQGAYICTGT 1161

Query: 89   NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWK-KNGQ 147
            NS G+A +  AT+ V  L +         +   G+T VLEC+   G P P V W   N +
Sbjct: 1162 NSAGSATA-TATIRVQGLPQISITPTNPAEFRVGETAVLECVAT-GEPLPTVQWMVMNNE 1219

Query: 148  TLLFDGDSRMHLVDGGNLV--IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
             +     +  ++ +  + +  IQ     DAG Y C A N AG           +++  L+
Sbjct: 1220 RVYQPIAAAFNMEEESSAMHYIQSVSMNDAGSYMCRAENGAG-----------YVEQELL 1268

Query: 206  TGPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
                +V+   G +  F C   G P    + WRR +    MP      + +G L +     
Sbjct: 1269 LRELEVIE--GETAVFSCTSPGTPAGYTITWRRVSQ--RMP--STVSISNGLLTIPQARS 1322

Query: 265  ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTM 324
               G+Y C   N  G       L V   PS+++SP +  V +G + R +C A G    T 
Sbjct: 1323 QYAGQYYCIVGNEHGYQQDLVTLYVLVLPSLSISPTTQTVTAGEIIRISCFAEGTQPITC 1382

Query: 325  FWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS-RNTIVCSAVNYAGSSFV 383
             WS  G                TA+  G  +L I+     D+ +   VCS  N AG  F 
Sbjct: 1383 EWSKYGG-----------SLPPTAIQSG-GILQISPATATDAGQYRCVCS--NTAG--FR 1426

Query: 384  RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR 443
               +TV     +  P +T  P+ +T  I     F C A  TP P I W  E   L   HR
Sbjct: 1427 DSYMTVRV---QVIPTVTAIPARETRAIGGSVEFSCQATGTPPPQITWEKEDGVLPAQHR 1483

Query: 444  RNVTNDGTLVLKDLDKSDSGTYTCVASSRHG------KYVWSGALLVDSPINPNIHFFRA 497
              +TN G L L  L   D G Y C A+++ G      +     A  V   +N  +H+ R 
Sbjct: 1484 --ITN-GVLSLISLRDGDEGRYVCTATNQAGSSKAYARLFLHAAPTVQITVNTTVHYIRV 1540

Query: 498  ADVSSL----PGPPTKPITHNVTDTSVTLS 523
             + ++      G PT  +T    ++ + +S
Sbjct: 1541 GETTTFECLSTGDPTPVVTWTKVNSEMPIS 1570



 Score =  108 bits (260), Expect = 8e-22
 Identities = 113/453 (24%), Positives = 172/453 (37%), Gaps = 58/453 (12%)

Query: 27   QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH-------SD 79
            + A L C A G P P ++W      +V +  R   P    F +      +H       +D
Sbjct: 1195 ETAVLECVATGEPLPTVQW------MVMNNERVYQPIAAAFNMEEESSAMHYIQSVSMND 1248

Query: 80   AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
            AG Y C A N  G            +LRE         +  +G+T V  C  P       
Sbjct: 1249 AGSYMCRAENGAGYVEQE------LLLRE--------LEVIEGETAVFSCTSPGTPAGYT 1294

Query: 140  VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
            + W++  Q +     S +  +  G L I  AR   AG+Y CI  N  G ++  + TL + 
Sbjct: 1295 ITWRRVSQRM----PSTVS-ISNGLLTIPQARSQYAGQYYCIVGNEHGYQQDLV-TLYVL 1348

Query: 200  IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL 259
            + P L   P       G  +   C   G       W  S  GG++P   ++    G L++
Sbjct: 1349 VLPSLSISPTTQTVTAGEIIRISCFAEGTQPITCEW--SKYGGSLPPTAIQ--SGGILQI 1404

Query: 260  DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGR 319
                  D G+Y C   N+ G   +   + V   P++   P       G    F+C ATG 
Sbjct: 1405 SPATATDAGQYRCVCSNTAGFRDSYMTVRVQVIPTVTAIPARETRAIGGSVEFSCQATGT 1464

Query: 320  PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379
            P P + W  E     + P   R       + +GV  L I+  D ++ R   VC+A N AG
Sbjct: 1465 PPPQITWEKEDG---VLPAQHR-------ITNGVLSL-ISLRDGDEGR--YVCTATNQAG 1511

Query: 380  SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-YFEGEAL 438
            SS    +L + +    P   IT   +   + +     F C +   P P++ W     E  
Sbjct: 1512 SSKAYARLFLHA---APTVQITVNTTVHYIRVGETTTFECLSTGDPTPVVTWTKVNSEMP 1568

Query: 439  IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
            I      V     L +  +  SD G Y C A++
Sbjct: 1569 IS----VVLQGARLTIPQVSLSDVGFYRCTATN 1597



 Score = 93.1 bits (221), Expect = 4e-17
 Identities = 83/317 (26%), Positives = 130/317 (41%), Gaps = 31/317 (9%)

Query: 165 LVIQDARQTDAGRYQCIARN--AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQ 222
           L I++ R  DAG +   A N   +GT E  +  +   ++  +I  P+ V    G +V F 
Sbjct: 690 LQIRNLRANDAGIFIFTASNRFGSGTAEVRLEVVGQAMR-VVINDPQTVEVPEGETVQFV 748

Query: 223 CR-VGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281
           CR +   P   + W RS   G +P      +  G L +D V L+D G+Y C   N     
Sbjct: 749 CRGISQTPAYTIAWSRS--DGTLPTNARDFM--GILTIDTVRLSDAGQYVCMGSNQRDTA 804

Query: 282 SASGYLTV---YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPG 338
            A   L V      P++ + P  + +  G+   F C ATG P PT+ WS          G
Sbjct: 805 DAYATLIVTSSVQEPTVRIEPRFIRITEGDRVEFRCIATGNPTPTLRWS----------G 854

Query: 339 MSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398
                 ++ + F+   +  I     +D      C A N AG + +R  L V+       P
Sbjct: 855 GQGGVLNSESTFEN-GLFVIPKARASDEAE-YFCEATNSAGMATIRTVLYVSPS---RVP 909

Query: 399 IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-YFEGEALIQNHRRNVTNDGTLVLKDL 457
            +T  P+++++      +F C A   P P   W   +G+        N    G LV+  +
Sbjct: 910 SVTISPASESVSEGERVIFYCQATGDPAPERTWSRIDGDMPSSAREEN----GYLVISAV 965

Query: 458 DKSDSGTYTCVASSRHG 474
                G Y C A++ HG
Sbjct: 966 TYEVEGVYRCTATNSHG 982



 Score = 73.3 bits (172), Expect = 4e-11
 Identities = 55/188 (29%), Positives = 85/188 (45%), Gaps = 19/188 (10%)

Query: 27   QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH-SDAGVYWC 85
            +  T  C + G P+P + W K    V S+   S++  G     R T  +V  SD G Y C
Sbjct: 1542 ETTTFECLSTGDPTPVVTWTK----VNSEMPISVVLQGA----RLTIPQVSLSDVGFYRC 1593

Query: 86   EATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
             ATN  G+ R+    L+V     +  + P ++ +  G T+   CL   G P P + W K+
Sbjct: 1594 TATNIVGS-RTSQVFLYVQAA-PQLTVVPSTRTAPVGSTLEFSCLAG-GFPTPEITWHKD 1650

Query: 146  GQTLLFDGD-SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL 204
                  DGD    + +D G L I + ++ D G Y CIA N  G+ E     +   + PY 
Sbjct: 1651 ------DGDLPDNYQIDNGLLTITNVKEADEGTYVCIATNQGGSTEHRARLVVGELIPYF 1704

Query: 205  ITGPEDVV 212
            +  P+  +
Sbjct: 1705 VQMPQSYI 1712



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 34/106 (32%), Positives = 44/106 (41%), Gaps = 8/106 (7%)

Query: 11   APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
            AP +   P   T         +C AGG P+P I W+K       D   +     GL  L 
Sbjct: 1613 APQLTVVPSTRTAPVGSTLEFSCLAGGFPTPEITWHKDD----GDLPDNYQIDNGL--LT 1666

Query: 71   ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPES 116
             T+ +  +D G Y C ATN  G+   R A L V  L   F   P+S
Sbjct: 1667 ITNVK-EADEGTYVCIATNQGGSTEHR-ARLVVGELIPYFVQMPQS 1710


>UniRef50_Q4T8B2 Cluster: Chromosome undetermined SCAF7849, whole
           genome shotgun sequence; n=3; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF7849,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 1319

 Score =  145 bits (351), Expect = 7e-33
 Identities = 124/460 (26%), Positives = 197/460 (42%), Gaps = 46/460 (10%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
           + P + E P  +T    +  +L C A G+P P   W K G  + SD     L A     L
Sbjct: 51  QPPVLSEVPKSLTAFSLEDISLPCEATGNPPPTFEWVKDGQRIRSDLASGTLQAKEDDLL 110

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
           +   G        Y C A+N YGTA ++   + V       + + + K++ +G++++L C
Sbjct: 111 QQFEGH-------YRCYASNIYGTAMTQIVHVIVEAQPVLLKQQKDHKRAYEGESLILSC 163

Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIARNAAGT 188
            PP  S  P ++W       +   D  M  +DG NL   +  ++D+ + Y C A+  A  
Sbjct: 164 NPPESSTPPFIHWMDKQMIHISQSDRVMVGLDG-NLYFSNLLKSDSRKDYMCNAQYLA-- 220

Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
               + TL                  T S+++    +  +P P+V W++  G      GR
Sbjct: 221 ---VMTTL------------------TESAISLTV-LPSEPTPEVEWKKKDGSLEETSGR 258

Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGN 308
               +      +++ L D+GEY C+A NS G  + S  +TV   P     P S     G 
Sbjct: 259 GDKYNRW-FHFESIGLKDDGEYECKARNSHGFTTHSFTVTVEAAPYWVKEPTSQLYSPGE 317

Query: 309 VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
             R  C A G P PT+ WS+ G      P    D+    +V  GV +L   D   +D+  
Sbjct: 318 TVRLDCQAEGIPTPTITWSINGQ-----PITEVDEEPRRSVSGGVLIL--RDVVFSDTA- 369

Query: 369 TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428
              C A N  GS+ +   L V    + PP I+T+      +      +  C A  +P P 
Sbjct: 370 VYQCEATNKHGSALLNTFLHVV---ELPPQILTSDGLLYKVTEGKNVLMDCEAFGSPRPH 426

Query: 429 IAWYFEGE-ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
           I W  E    L+ N R ++  +GTLV+ ++D  D+G Y+C
Sbjct: 427 ITWEAEDRLPLLSNPRVSLMTNGTLVMSEVDHDDAGVYSC 466



 Score =  126 bits (304), Expect = 4e-27
 Identities = 90/297 (30%), Positives = 147/297 (49%), Gaps = 19/297 (6%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG---VLVVSDTHRSILP 62
           VT   APY +++P     +  +   L+C+A G P+P I W   G     V  +  RS+  
Sbjct: 296 VTVEAAPYWVKEPTSQLYSPGETVRLDCQAEGIPTPTITWSINGQPITEVDEEPRRSV-- 353

Query: 63  AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
           +GG+  LR     V SD  VY CEATN +G+A   N  LHV  L  +    +    +  +
Sbjct: 354 SGGVLILRDV---VFSDTAVYQCEATNKHGSA-LLNTFLHVVELPPQILTSDGLLYKVTE 409

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
           G  V+++C    GSP P++ W+   +  L   + R+ L+  G LV+ +    DAG Y C 
Sbjct: 410 GKNVLMDC-EAFGSPRPHITWEAEDRLPLL-SNPRVSLMTNGTLVMSEVDHDDAGVYSCS 467

Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP-LP--DVLWRRS 238
            ++      S  A L+++ +  ++  PED++   G+SV   C+   DP LP   V+W++ 
Sbjct: 468 VKH--NNNISINAHLEVYNRTVILKPPEDLLILRGTSVLLPCKFSTDPRLPKAQVVWKKD 525

Query: 239 AGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
                 +    +   LD  +L + +V  +D   YSCE  +++  V+A+G +TV D P
Sbjct: 526 GIKLMESKAANKYSFLDTDTLIVSDVQFSDSAPYSCEVISALDHVTATGSITVVDRP 582



 Score =  105 bits (251), Expect = 1e-20
 Identities = 127/493 (25%), Positives = 196/493 (39%), Gaps = 59/493 (11%)

Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
           + L  LP    P P V WKK   +L  +   R    +      +     D G Y+C ARN
Sbjct: 230 ISLTVLP--SEPTPEVEWKKKDGSLE-ETSGRGDKYNRW-FHFESIGLKDDGEYECKARN 285

Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
           + G    +  T+ +   PY +  P   +   G +V   C+  G P P + W  S  G   
Sbjct: 286 SHGFTTHSF-TVTVEAAPYWVKEPTSQLYSPGETVRLDCQAEGIPTPTITW--SING--Q 340

Query: 245 PLGRV-----KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLS 298
           P+  V     + +  G L L +V+ +D   Y CEA N  G+   + +L V + PP I  S
Sbjct: 341 PITEVDEEPRRSVSGGVLILRDVVFSDTAVYQCEATNKHGSALLNTFLHVVELPPQILTS 400

Query: 299 PNSV-NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
              +  V  G      C A G P P + W  E       P +S  +   + + +G  V++
Sbjct: 401 DGLLYKVTEGKNVLMDCEAFGSPRPHITWEAEDR----LPLLSNPR--VSLMTNGTLVMS 454

Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
             D   +D      CS V +  +  +   L V +       +I   P +  +   +  + 
Sbjct: 455 EVD---HDDAGVYSCS-VKHNNNISINAHLEVYNRT-----VILKPPEDLLILRGTSVLL 505

Query: 418 PC---TAICTPEPIIAWYFEGEALIQNHRRN---VTNDGTLVLKDLDKSDSGTYTCVASS 471
           PC   T    P+  + W  +G  L+++   N     +  TL++ D+  SDS  Y+C   S
Sbjct: 506 PCKFSTDPRLPKAQVVWKKDGIKLMESKAANKYSFLDTDTLIVSDVQFSDSAPYSCEVIS 565

Query: 472 RHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIG 531
                  +G++                 V   P PP       VTD S+TL+W+      
Sbjct: 566 ALDHVTATGSI----------------TVVDRPDPPKHLFLSEVTDDSLTLNWTPGPS-H 608

Query: 532 SSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTEN 591
           +S I  + VE  SRE     +T +    W    +    + ++  SL P  TY F V T N
Sbjct: 609 NSPITEFIVE--SREE---QHTEQEKWKWEETQKVPPNSQHLKLSLRPYCTYRFRVITVN 663

Query: 592 SHGLSGPSPVSDS 604
             G S PS  SDS
Sbjct: 664 EVGRSDPSEPSDS 676



 Score =  104 bits (250), Expect = 1e-20
 Identities = 85/338 (25%), Positives = 142/338 (42%), Gaps = 17/338 (5%)

Query: 79  DAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
           D G Y C+A NS+G T  S   T+  A    +   EP S+  + G+TV L+C    G P 
Sbjct: 275 DDGEYECKARNSHGFTTHSFTVTVEAAPYWVK---EPTSQLYSPGETVRLDC-QAEGIPT 330

Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
           P + W  NGQ +    +     V GG L+++D   +D   YQC A N  G+         
Sbjct: 331 PTITWSINGQPITEVDEEPRRSVSGGVLILRDVVFSDTAVYQCEATNKHGSALLNTFLHV 390

Query: 198 IHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS 256
           + + P ++T    +   T G +V   C   G P P + W        +   RV ++ +G+
Sbjct: 391 VELPPQILTSDGLLYKVTEGKNVLMDCEAFGSPRPHITWEAEDRLPLLSNPRVSLMTNGT 450

Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC-- 314
           L +  V   D G YSC  +++   +S + +L VY+   I   P  + +  G      C  
Sbjct: 451 LVMSEVDHDDAGVYSCSVKHN-NNISINAHLEVYNRTVILKPPEDLLILRGTSVLLPCKF 509

Query: 315 -TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
            T    P+  + W  +G +  +    + +KY     F     L ++D   +DS     C 
Sbjct: 510 STDPRLPKAQVVWKKDGIK--LMESKAANKYS----FLDTDTLIVSDVQFSDSA-PYSCE 562

Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
            ++        G +TV    D P  +  +  ++ +L +
Sbjct: 563 VISALDHVTATGSITVVDRPDPPKHLFLSEVTDDSLTL 600



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 27/95 (28%), Positives = 42/95 (44%), Gaps = 8/95 (8%)

Query: 382 FVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN 441
           F +G + +  D  +PP +++  P + T         PC A   P P   W  +G+ +   
Sbjct: 38  FAQGAIEIPKDLSQPP-VLSEVPKSLTAFSLEDISLPCEATGNPPPTFEWVKDGQRI--- 93

Query: 442 HRRNVTNDGTLVLK--DLDKSDSGTYTCVASSRHG 474
             R+    GTL  K  DL +   G Y C AS+ +G
Sbjct: 94  --RSDLASGTLQAKEDDLLQQFEGHYRCYASNIYG 126


>UniRef50_UPI0000F2E6F1 Cluster: PREDICTED: similar to L1 cell
           adhesion molecule; n=1; Monodelphis domestica|Rep:
           PREDICTED: similar to L1 cell adhesion molecule -
           Monodelphis domestica
          Length = 1344

 Score =  144 bits (349), Expect = 1e-32
 Identities = 132/483 (27%), Positives = 198/483 (40%), Gaps = 37/483 (7%)

Query: 10  EAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI---LPAGG 65
           + P I EQ P  + V       L C A G P    RW K  +    +        + +G 
Sbjct: 123 QPPNITEQSPEKLVVFPTDDIVLKCEASGKPEVQFRWTKENIHFSPEKELGATTHINSGS 182

Query: 66  LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
                 T        G Y C A+N  GTA S    L      +  + + +  +  +G +V
Sbjct: 183 FIITGNTSNFAQRYQGTYRCFASNRLGTAMSHEIHLVAEGAPKWPKEKVQPFEVEEGQSV 242

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARN 184
           VL C PP  + +P +YW  N +      D R+ +   GNL   +    D+   Y C A  
Sbjct: 243 VLPCNPPASAVQPRIYWM-NSRIFHIAQDERVTMGQNGNLYFANVLTNDSHSDYICHAHF 301

Query: 185 AAGTRESAIATLKIHIKPY--------LITGPEDV----VAQTGSSVTFQCRVGGDPLPD 232
                      + + +KP          +  PE +    VA  G  +  +C   G P P 
Sbjct: 302 LGARTIMQKEPIDLRVKPTNNMIYRRPRLLLPEGLTSRLVALRGQPLVLECIAEGFPTPT 361

Query: 233 VLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
           + W  S     M  GRV   + + +LRL  V   D+GEY C AEN++G+     Y+TV  
Sbjct: 362 IKW--SYPSNQMQAGRVTYQNFNKTLRLVRVEEEDDGEYRCWAENTLGSAQHVYYVTVEA 419

Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
            P     P S+ +  G  AR  C   GRP P + W + G   +    ++RD      V  
Sbjct: 420 APYWLQEPESLVLAPGETARLNCQVQGRPRPMVTWRING---VSLENLTRD--DKLRVQG 474

Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL-P 410
           G  +L  ++   ND+  T  C A N  G       ++V      P  I+T  P N+T   
Sbjct: 475 GALIL--SNVQPNDTMVT-QCEARNKHGLLLANAYISVV---QLPTKILT--PDNKTYRE 526

Query: 411 IK-SMAVFPCTAICTPEPIIAWYFEGEA-LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468
           ++ S A   C A   P P I W    +A ++Q+ R     +GTL ++DL  +D+G+Y C 
Sbjct: 527 VQGSTAYLLCNAFGVPMPSIQWLNRDQATVLQDERFVPYANGTLAIRDLQTNDTGSYFCQ 586

Query: 469 ASS 471
           A +
Sbjct: 587 ADN 589



 Score =  143 bits (346), Expect = 3e-32
 Identities = 198/849 (23%), Positives = 316/849 (37%), Gaps = 93/849 (10%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSP-SPAIRWYKGGVLVVSDTHRSILPAG 64
           V  G   +  E+     V   Q   L C    S   P I W    +  ++   R  +   
Sbjct: 219 VAEGAPKWPKEKVQPFEVEEGQSVVLPCNPPASAVQPRIYWMNSRIFHIAQDERVTMGQN 278

Query: 65  G-LFFLRATHGRVHSDAGVYWCEA--TNSYGTARSRNATLHVA-----VLREEFRLEPES 116
           G L+F        HSD   Y C A    +    +     L V      + R    L PE 
Sbjct: 279 GNLYFANVLTNDSHSD---YICHAHFLGARTIMQKEPIDLRVKPTNNMIYRRPRLLLPEG 335

Query: 117 KQSA----QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ 172
             S     +G  +VLEC+   G P P + W      +     +  +      L +    +
Sbjct: 336 LTSRLVALRGQPLVLECIA-EGFPTPTIKWSYPSNQMQAGRVTYQNF--NKTLRLVRVEE 392

Query: 173 TDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
            D G Y+C A N  G+ +  +  + +   PY +  PE +V   G +    C+V G P P 
Sbjct: 393 EDDGEYRCWAENTLGSAQH-VYYVTVEAAPYWLQEPESLVLAPGETARLNCQVQGRPRPM 451

Query: 233 VLWR-RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
           V WR       N+       +  G+L L NV   D     CEA N  G + A+ Y++V  
Sbjct: 452 VTWRINGVSLENLTRDDKLRVQGGALILSNVQPNDTMVTQCEARNKHGLLLANAYISVVQ 511

Query: 292 PPSINLSPNSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
            P+  L+P++       G+ A   C A G P P++ W      T++      +++   A 
Sbjct: 512 LPTKILTPDNKTYREVQGSTAYLLCNAFGVPMPSIQWLNRDQATVL----QDERFVPYA- 566

Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409
            +G   L I D   ND+  +  C A N      ++  L V          I  GP ++T+
Sbjct: 567 -NGT--LAIRDLQTNDT-GSYFCQADNDQNRVSIKAHLQVKEATQ-----IKKGPEDRTV 617

Query: 410 PIKSMAVFPCTAICTPEPIIA--WYFEGEALIQNHRRN--VTNDGTLVLKDLDKSDSGTY 465
              S   FPC     P   I   WY+  + +   ++ +  +  +  L +  LD +D G Y
Sbjct: 618 KKGSNVNFPCLVSFDPSLNIQIDWYWNDQNIKDFYKEDKYLIKEEELTIISLDYADQGNY 677

Query: 466 TCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWS 525
           +CVA +          +LV               V S PGP  +   +   D  V LSWS
Sbjct: 678 SCVAKTALDSVEKKATVLV---------------VGS-PGPVGQLELYKQKDFHVQLSWS 721

Query: 526 QNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMF 585
              +  +S I  Y +E   R    G         W  +A            L P + Y F
Sbjct: 722 PAEE-HNSPIEKYNIEFEDRTMEPGT--------WYPLATVPGNETSTRLKLSPFVHYNF 772

Query: 586 IVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPID 645
            V   N  G S PSP S+   +   S      T V       NN++              
Sbjct: 773 RVIANNKFGASEPSPDSEPF-ITPKSVPEKNPTNVKGEGNETNNMV-------------- 817

Query: 646 SKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEF 705
                + W+ L +    G  + +R       E E + ++     S + +++   +  YE 
Sbjct: 818 -----ITWKPLKWIDWNGPELKYRVQWRQKNESEWREVMVR--ASKYVVSNTPTFVPYEI 870

Query: 706 FLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIIT 765
            +    +  +G   +  +  + +DVP   PI + + +LN TTV +KW P +L    G + 
Sbjct: 871 KVQAINEVGKGPDPHIVIGYSGEDVPQAIPI-VAIELLNATTVRIKWEPVDLNEVRGHLR 929

Query: 766 GYNVVVNWLDVPANKSMVAINTTV----HQATSLIMTNLTSGVSYSVQIAAETIIGLGPF 821
           GY V   W++   ++S      T+      A   ++ +L     YSV +       LGP 
Sbjct: 930 GYRVTYWWVNSRWSRSKRHTPKTIIDKPASAMEAVLPDLRPYSIYSVHVQVFNSRSLGPP 989

Query: 822 SQKVYFNID 830
           S+ + F  +
Sbjct: 990 SETIKFETE 998



 Score =  106 bits (254), Expect = 4e-21
 Identities = 88/295 (29%), Positives = 131/295 (44%), Gaps = 14/295 (4%)

Query: 5   YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA- 63
           YVT   APY +++P  + +A  + A LNC+  G P P + W   GV + + T    L   
Sbjct: 414 YVTVEAAPYWLQEPESLVLAPGETARLNCQVQGRPRPMVTWRINGVSLENLTRDDKLRVQ 473

Query: 64  GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQ 121
           GG   L        +D  V  CEA N +G   + NA + V  L  +  L P++K  +  Q
Sbjct: 474 GGALILSNVQ---PNDTMVTQCEARNKHGLLLA-NAYISVVQLPTKI-LTPDNKTYREVQ 528

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
           G T  L C    G P P++ W    Q  +   D R      G L I+D +  D G Y C 
Sbjct: 529 GSTAYLLC-NAFGVPMPSIQWLNRDQATVLQ-DERFVPYANGTLAIRDLQTNDTGSYFCQ 586

Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL--WRRSA 239
           A N    R S  A L++     +  GPED   + GS+V F C V  DP  ++   W  + 
Sbjct: 587 ADNDQ-NRVSIKAHLQVKEATQIKKGPEDRTVKKGSNVNFPCLVSFDPSLNIQIDWYWND 645

Query: 240 GGGNMPLGRVK-VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
                     K ++ +  L + ++  AD+G YSC A+ ++ +V     + V   P
Sbjct: 646 QNIKDFYKEDKYLIKEEELTIISLDYADQGNYSCVAKTALDSVEKKATVLVVGSP 700



 Score = 41.9 bits (94), Expect = 0.10
 Identities = 35/129 (27%), Positives = 56/129 (43%), Gaps = 10/129 (7%)

Query: 694  ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
            +  LR Y+ Y   +  F  +  G PS +   +T + VPD P  ++ +  L+ T + L W 
Sbjct: 965  LPDLRPYSIYSVHVQVFNSRSLGPPSETIKFETEEGVPDRPQ-SLNLRRLSDTALQLSWR 1023

Query: 754  PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTS---GVSYSVQI 810
            PP     NG + GY ++      P N+       T     + +M NL+       Y  Q+
Sbjct: 1024 PP--LNPNGELKGYQLIYR----PFNQEPEENEMTEFLPPTTLMFNLSDLKPQTLYRFQL 1077

Query: 811  AAETIIGLG 819
             A T +G G
Sbjct: 1078 RATTKVGPG 1086


>UniRef50_UPI0000F1EDBC Cluster: PREDICTED: similar to adlican; n=1;
            Danio rerio|Rep: PREDICTED: similar to adlican - Danio
            rerio
          Length = 1903

 Score =  144 bits (348), Expect = 2e-32
 Identities = 132/476 (27%), Positives = 210/476 (44%), Gaps = 36/476 (7%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWY---KGGVLVVSDTHRSI-LPAGGLFFLRATHGR 75
            DVTV     A L C+A G P P I W    +  +  VS+T + I L A G   ++ T+  
Sbjct: 1035 DVTVYIGNTALLQCQAQGLPIPNISWMLPDRSMLRSVSNTQQKIMLLANGTLQIKQTN-- 1092

Query: 76   VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVLECLPPRG 134
             + D GVY C A+N+ G A   +  L +  L    + +  E+   + G   ++ C    G
Sbjct: 1093 -YLDTGVYKCIASNAAG-ADMLSVRLQITALAPVIQEQRWENYTLSDGHAALIHCTA-NG 1149

Query: 135  SPEPNVYWKKNGQTLLFDG---DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
            +P P V W  +    L      +S + +   G L I++    D+G Y+C+A ++ G  + 
Sbjct: 1150 APNPTVRWVTSSGMQLRPSQFVNSNLFVFPNGTLFIRNPTVKDSGIYECVAVSSVGMAKR 1209

Query: 192  AIATLKIHIKP----YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG---GGNM 244
            ++  L++         L T         G  ++  C   G P P ++WR  A        
Sbjct: 1210 SV-NLQVKRNSGSARILSTSAHSTDVHYGDQLSLNCSASGSPTPRIIWRTPAKKLVDSYY 1268

Query: 245  PLGR-VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS--INLSPNS 301
               R +KVL +G+L + +V   DEGEY C A N+ G       +TV    +   + S + 
Sbjct: 1269 SFDRRMKVLSNGTLTITSVTEQDEGEYLCAARNNAGDDYVLLKVTVMMKAAKIDHKSLSE 1328

Query: 302  VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA----VFDGVTVLT 357
              V  G   +  C A+G P P + WS+  + T+I   +S DK    A    +FD  T L 
Sbjct: 1329 HKVLYGGELKVDCIASGLPNPEVSWSLP-DGTMINSVLSSDKNTIRAKRYVMFDNGT-LY 1386

Query: 358  INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
            +N+    +      C A N  G   ++  + V +D    P I  N  S   +     A+ 
Sbjct: 1387 LNEVGMKE-EGDYTCYAKNQMGKDEMKVHIKVLAD---APVIRNNAYSVIKVTYGETAIL 1442

Query: 418  PCTAICTPEPIIAWYFEGEALI--QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
             C+A   P P+I W    + +I    ++  ++NDGTL +    K +SG YTC+A S
Sbjct: 1443 NCSAKGEPTPVITWISPDKKVIVPMTNKYQISNDGTLHIHKTQKINSGNYTCMARS 1498



 Score =  134 bits (324), Expect = 1e-29
 Identities = 145/606 (23%), Positives = 245/606 (40%), Gaps = 54/606 (8%)

Query: 21   VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI----LPAGGLFFLRATHGRV 76
            V+V       L C + G P P + W K     V  T+  +    +   G F +R  H + 
Sbjct: 939  VSVNAGTDVQLPCNSVGEPRPLLTWTKVSTGAVMSTNTKVQRFEVHPNGTFTIRNVHLQ- 997

Query: 77   HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
              D G Y C A+N++GT +     + +A +        +      G+T +L+C   +G P
Sbjct: 998  --DRGQYLCSASNAHGTDKMMVTLVVLAHVPRMTSPRHQDVTVYIGNTALLQC-QAQGLP 1054

Query: 137  EPNVYWKKNGQTLL---FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
             PN+ W    +++L    +   ++ L+  G L I+     D G Y+CIA NAAG    ++
Sbjct: 1055 IPNISWMLPDRSMLRSVSNTQQKIMLLANGTLQIKQTNYLDTGVYKCIASNAAGADMLSV 1114

Query: 194  ATLKIHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK-- 250
                  + P +     E+     G +    C   G P P V W  S+G    P   V   
Sbjct: 1115 RLQITALAPVIQEQRWENYTLSDGHAALIHCTANGAPNPTVRWVTSSGMQLRPSQFVNSN 1174

Query: 251  --VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY----DPPSINLSPNSVNV 304
              V  +G+L + N  + D G Y C A +SVG    S  L V         ++ S +S +V
Sbjct: 1175 LFVFPNGTLFIRNPTVKDSGIYECVAVSSVGMAKRSVNLQVKRNSGSARILSTSAHSTDV 1234

Query: 305  ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
              G+     C+A+G P P + W     + ++    S D+         +T+ ++ + D+ 
Sbjct: 1235 HYGDQLSLNCSASGSPTPRIIWRTPAKK-LVDSYYSFDRRMKVLSNGTLTITSVTEQDEG 1293

Query: 365  DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
            +     +C+A N AG  +V  K+TV     +   I     S   +         C A   
Sbjct: 1294 E----YLCAARNNAGDDYVLLKVTVMM---KAAKIDHKSLSEHKVLYGGELKVDCIASGL 1346

Query: 425  PEPIIAWYFEGEALIQN-----------HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
            P P ++W      +I +            R  + ++GTL L ++   + G YTC A ++ 
Sbjct: 1347 PNPEVSWSLPDGTMINSVLSSDKNTIRAKRYVMFDNGTLYLNEVGMKEEGDYTCYAKNQM 1406

Query: 474  GKYVWSG--ALLVDSPINPN-------IHFFRAADVS-SLPGPPTKPITHNVTDTSVTLS 523
            GK        +L D+P+  N       + +   A ++ S  G PT  IT    D  V + 
Sbjct: 1407 GKDEMKVHIKVLADAPVIRNNAYSVIKVTYGETAILNCSAKGEPTPVITWISPDKKVIVP 1466

Query: 524  WSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVV-KSLIPGIT 582
             +   +I +   L     +   + ++  N    +R  V I R+V     +V   +I G  
Sbjct: 1467 MTNKYQISNDGTL----HIHKTQKINSGNYTCMARSVVGIDRKVVLVEVLVFPPVINGFE 1522

Query: 583  YMFIVR 588
            +  I+R
Sbjct: 1523 HPGIIR 1528



 Score =  120 bits (289), Expect = 2e-25
 Identities = 125/497 (25%), Positives = 195/497 (39%), Gaps = 47/497 (9%)

Query: 8    SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-----DTHRSILP 62
            SG A  +        V      +LNC A GSP+P I W      +V      D    +L 
Sbjct: 1219 SGSARILSTSAHSTDVHYGDQLSLNCSASGSPTPRIIWRTPAKKLVDSYYSFDRRMKVLS 1278

Query: 63   AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ- 121
             G L     T      D G Y C A N+ G        L V V+ +  +++ +S    + 
Sbjct: 1279 NGTLTITSVT----EQDEGEYLCAARNNAG---DDYVLLKVTVMMKAAKIDHKSLSEHKV 1331

Query: 122  --GDTVVLECLPPRGSPEPNVYWKKNGQTLL---FDGD------SRMHLVDGGNLVIQDA 170
              G  + ++C+   G P P V W     T++      D       R  + D G L + + 
Sbjct: 1332 LYGGELKVDCI-ASGLPNPEVSWSLPDGTMINSVLSSDKNTIRAKRYVMFDNGTLYLNEV 1390

Query: 171  RQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDP 229
               + G Y C A+N  G  E  +    +   P +      V+  T G +    C   G+P
Sbjct: 1391 GMKEEGDYTCYAKNQMGKDEMKVHIKVLADAPVIRNNAYSVIKVTYGETAILNCSAKGEP 1450

Query: 230  LPDVLWRRSAGGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
             P + W        +P+  + ++ +DG+L +      + G Y+C A + VG       + 
Sbjct: 1451 TPVITWISPDKKVIVPMTNKYQISNDGTLHIHKTQKINSGNYTCMARSVVGIDRKVVLVE 1510

Query: 289  V-YDPPSIN--LSPNSVNVESGNVAR--FTCTATGRPEPTMFWSVEGNRTIIFPGM-SRD 342
            V   PP IN    P  +   +    R  F C A G P P + W    N  +  P   SR 
Sbjct: 1511 VLVFPPVINGFEHPGIIRKTAVRDQRVLFDCKANGNPFPRIIWLFPNNVVLPAPYYGSRI 1570

Query: 343  KYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN 402
              H     D +  + ++D+ +      ++C A N  G + +  KL VT D  +P   + N
Sbjct: 1571 TVHRNGTLD-IHAVRMSDSVE------LICIARNEFGETKLHVKLEVTEDIIKPQ--LRN 1621

Query: 403  GPSNQ-TLPIKSMAVFPCTAICTPEPIIAWYF-EGEALIQN---HRRNVTNDGTLVLKDL 457
             P++   L I       C+    P P I W    G +L Q     R +  +DG L++K+ 
Sbjct: 1622 SPTDSIQLTIGKPTTLNCSIEGNPAPQITWTLPNGTSLYQGTTFSRFHHRSDGALLIKEP 1681

Query: 458  DKSDSGTYTCVASSRHG 474
              SD+G Y CV  +  G
Sbjct: 1682 SSSDAGLYRCVGRNSGG 1698



 Score =  117 bits (281), Expect = 2e-24
 Identities = 114/481 (23%), Positives = 204/481 (42%), Gaps = 43/481 (8%)

Query: 31   LNCRAGGSPSPAIRW-YKGGVL---VVSDTHRSILPAGGLFFLRAT---HGRVHSDAGVY 83
            ++C A G P+P + W    G +   V+S    +I     + F   T   +     + G Y
Sbjct: 1339 VDCIASGLPNPEVSWSLPDGTMINSVLSSDKNTIRAKRYVMFDNGTLYLNEVGMKEEGDY 1398

Query: 84   WCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GDTVVLECLPPRGSPEPNV 140
             C A N  G    +   +H+ VL +   +   +    +   G+T +L C   +G P P +
Sbjct: 1399 TCYAKNQMGKDEMK---VHIKVLADAPVIRNNAYSVIKVTYGETAILNC-SAKGEPTPVI 1454

Query: 141  YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
             W    + ++    ++  + + G L I   ++ ++G Y C+AR+  G  +  +  +++ +
Sbjct: 1455 TWISPDKKVIVPMTNKYQISNDGTLHIHKTQKINSGNYTCMARSVVGI-DRKVVLVEVLV 1513

Query: 201  KPYLITGPE--DVVAQTG---SSVTFQCRVGGDPLPDVLWRRSAGGGNMPL----GRVKV 251
             P +I G E   ++ +T      V F C+  G+P P ++W        +P      R+ V
Sbjct: 1514 FPPVINGFEHPGIIRKTAVRDQRVLFDCKANGNPFPRIIW-LFPNNVVLPAPYYGSRITV 1572

Query: 252  LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLSP-NSVNVESG 307
              +G+L +  V ++D  E  C A N  G       L V +    P +  SP +S+ +  G
Sbjct: 1573 HRNGTLDIHAVRMSDSVELICIARNEFGETKLHVKLEVTEDIIKPQLRNSPTDSIQLTIG 1632

Query: 308  NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
                  C+  G P P + W++  N T ++ G +  ++H  +  DG   L I +   +D+ 
Sbjct: 1633 KPTTLNCSIEGNPAPQITWTLP-NGTSLYQGTTFSRFHHRS--DG--ALLIKEPSSSDA- 1686

Query: 368  NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427
                C   N  G  FV   +T+ S  +R P I     S  ++         C +   P P
Sbjct: 1687 GLYRCVGRNSGG--FVERNVTLVS--NRKPEITNQYSSLLSIINGEDLHLDCVSDAHPPP 1742

Query: 428  IIAWYFEGEALI----QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
             + W      ++     + R +V N+GTL +      D GTY C  S+ HG    S +++
Sbjct: 1743 KLTWTLPSGVVLSRAQSSGRHSVLNNGTLSIHRTSVYDRGTYRCQISNDHGSSSLSVSVI 1802

Query: 484  V 484
            V
Sbjct: 1803 V 1803



 Score =  109 bits (262), Expect = 5e-22
 Identities = 125/485 (25%), Positives = 197/485 (40%), Gaps = 38/485 (7%)

Query: 10   EAPYIIEQPLDVT-VARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLF 67
            +AP I      V  V   + A LNC A G P+P I W      ++V  T++  +   G  
Sbjct: 1420 DAPVIRNNAYSVIKVTYGETAILNCSAKGEPTPVITWISPDKKVIVPMTNKYQISNDGTL 1479

Query: 68   FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR---EEFRLEPESKQSAQGDT 124
             +  T  +++S  G Y C A +  G  R +   + V V       F      +++A  D 
Sbjct: 1480 HIHKTQ-KINS--GNYTCMARSVVGIDR-KVVLVEVLVFPPVINGFEHPGIIRKTAVRDQ 1535

Query: 125  VVLECLPPRGSPEPNVYWKKNGQTLL---FDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
             VL      G+P P + W      +L   + G SR+ +   G L I   R +D+    CI
Sbjct: 1536 RVLFDCKANGNPFPRIIWLFPNNVVLPAPYYG-SRITVHRNGTLDIHAVRMSDSVELICI 1594

Query: 182  ARNAAGTRESAIA--TLKIHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRS 238
            ARN  G  +  +     +  IKP L   P D +  T G   T  C + G+P P + W   
Sbjct: 1595 ARNEFGETKLHVKLEVTEDIIKPQLRNSPTDSIQLTIGKPTTLNCSIEGNPAPQITWTLP 1654

Query: 239  AGGG---NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295
             G          R     DG+L +     +D G Y C   NS G V  +  L     P I
Sbjct: 1655 NGTSLYQGTTFSRFHHRSDGALLIKEPSSSDAGLYRCVGRNSGGFVERNVTLVSNRKPEI 1714

Query: 296  -NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
             N   + +++ +G      C +   P P + W++     ++    S  ++   +V +  T
Sbjct: 1715 TNQYSSLLSIINGEDLHLDCVSDAHPPPKLTWTLPSG-VVLSRAQSSGRH---SVLNNGT 1770

Query: 355  VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
             L+I+ T   D R T  C   N  GSS +   + V +     PP IT+GP+  T     +
Sbjct: 1771 -LSIHRTSVYD-RGTYRCQISNDHGSSSLSVSVIVIAY----PPRITSGPAAVTYGRVGV 1824

Query: 415  AV-FPCTAICTPEPIIAWYF-EGEAL---IQNH---RRNVTNDGTLVLKDLDKSDSGTYT 466
            A+   C ++ +P   + W   +G  L   +Q      +++   G L +      DSG Y 
Sbjct: 1825 ALTLDCRSLASPRAEVVWQMPDGLQLKVDVQPRLYGNKHLHPQGVLQIHSPSSRDSGVYK 1884

Query: 467  CVASS 471
            C A +
Sbjct: 1885 CTAKN 1889



 Score =  103 bits (246), Expect = 4e-20
 Identities = 96/371 (25%), Positives = 150/371 (40%), Gaps = 19/371 (5%)

Query: 22   TVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
            T  R Q    +C+A G+P P I W +   V++ +  + S +       L   H    SD+
Sbjct: 1530 TAVRDQRVLFDCKANGNPFPRIIWLFPNNVVLPAPYYGSRITVHRNGTLDI-HAVRMSDS 1588

Query: 81   GVYWCEATNSYGTARSRNATLHVA--VLREEFRLEP-ESKQSAQGDTVVLECLPPRGSPE 137
                C A N +G  +  +  L V   +++ + R  P +S Q   G    L C    G+P 
Sbjct: 1589 VELICIARNEFGETKL-HVKLEVTEDIIKPQLRNSPTDSIQLTIGKPTTLNC-SIEGNPA 1646

Query: 138  PNVYWKKNGQTLLFDGD--SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195
            P + W     T L+ G   SR H    G L+I++   +DAG Y+C+ RN+ G  E  + T
Sbjct: 1647 PQITWTLPNGTSLYQGTTFSRFHHRSDGALLIKEPSSSDAGLYRCVGRNSGGFVERNV-T 1705

Query: 196  LKIHIKPYLITGPEDVVA-QTGSSVTFQCRVGGDPLPDVLWRRSAG---GGNMPLGRVKV 251
            L  + KP +      +++   G  +   C     P P + W   +G         GR  V
Sbjct: 1706 LVSNRKPEITNQYSSLLSIINGEDLHLDCVSDAHPPPKLTWTLPSGVVLSRAQSSGRHSV 1765

Query: 252  LDDGSLRLDNVILADEGEYSCEAENSVGAVSAS-GYLTVYDPPSINLSPNSVNVESGNVA 310
            L++G+L +    + D G Y C+  N  G+ S S   + +  PP I   P +V      VA
Sbjct: 1766 LNNGTLSIHRTSVYDRGTYRCQISNDHGSSSLSVSVIVIAYPPRITSGPAAVTYGRVGVA 1825

Query: 311  -RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
                C +   P   + W +     +      R   +         VL I+     DS   
Sbjct: 1826 LTLDCRSLASPRAEVVWQMPDGLQLKVDVQPR--LYGNKHLHPQGVLQIHSPSSRDS-GV 1882

Query: 370  IVCSAVNYAGS 380
              C+A N  GS
Sbjct: 1883 YKCTAKNVLGS 1893



 Score = 88.6 bits (210), Expect = 9e-16
 Identities = 80/293 (27%), Positives = 126/293 (43%), Gaps = 20/293 (6%)

Query: 12   PYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILP--AGGLF 67
            P +   P D + +   +P TLNC   G+P+P I W    G  +   T  S     + G  
Sbjct: 1617 PQLRNSPTDSIQLTIGKPTTLNCSIEGNPAPQITWTLPNGTSLYQGTTFSRFHHRSDGAL 1676

Query: 68   FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVV 126
             ++       SDAG+Y C   NS G    RN TL V+  + E   +  S  S   G+ + 
Sbjct: 1677 LIKEPSS---SDAGLYRCVGRNSGGFVE-RNVTL-VSNRKPEITNQYSSLLSIINGEDLH 1731

Query: 127  LECLPPRGSPEPNVYWKKNGQTLLFDGDS--RMHLVDGGNLVIQDARQTDAGRYQCIARN 184
            L+C+     P P + W      +L    S  R  +++ G L I      D G Y+C   N
Sbjct: 1732 LDCVSD-AHPPPKLTWTLPSGVVLSRAQSSGRHSVLNNGTLSIHRTSVYDRGTYRCQISN 1790

Query: 185  AAGTRESAIATLKIHIKPYLITGPEDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSAG--- 240
              G+   +++ + I   P + +GP  V   + G ++T  CR    P  +V+W+   G   
Sbjct: 1791 DHGSSSLSVSVIVIAYPPRITSGPAAVTYGRVGVALTLDCRSLASPRAEVVWQMPDGLQL 1850

Query: 241  -GGNMP--LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290
                 P   G   +   G L++ +    D G Y C A+N +G+ S S Y+ V+
Sbjct: 1851 KVDVQPRLYGNKHLHPQGVLQIHSPSSRDSGVYKCTAKNVLGSDSRSTYVYVF 1903



 Score = 54.4 bits (125), Expect = 2e-05
 Identities = 44/182 (24%), Positives = 80/182 (43%), Gaps = 17/182 (9%)

Query: 300  NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPG--MSRDKYHATAVFDGVTVLT 357
            ++V+V +G   +  C + G P P + W+      ++     + R + H    F      T
Sbjct: 937  HTVSVNAGTDVQLPCNSVGEPRPLLTWTKVSTGAVMSTNTKVQRFEVHPNGTF------T 990

Query: 358  INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
            I +    D R   +CSA N  G+  +   L V +     P + +    + T+ I + A+ 
Sbjct: 991  IRNVHLQD-RGQYLCSASNAHGTDKMMVTLVVLA---HVPRMTSPRHQDVTVYIGNTALL 1046

Query: 418  PCTAICTPEPIIAWYFEGEAL---IQNHRRNV--TNDGTLVLKDLDKSDSGTYTCVASSR 472
             C A   P P I+W     ++   + N ++ +    +GTL +K  +  D+G Y C+AS+ 
Sbjct: 1047 QCQAQGLPIPNISWMLPDRSMLRSVSNTQQKIMLLANGTLQIKQTNYLDTGVYKCIASNA 1106

Query: 473  HG 474
             G
Sbjct: 1107 AG 1108


>UniRef50_Q4RVM2 Cluster: Chromosome 9 SCAF14991, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 9
           SCAF14991, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 1049

 Score =  144 bits (348), Expect = 2e-32
 Identities = 131/459 (28%), Positives = 197/459 (42%), Gaps = 35/459 (7%)

Query: 44  RWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103
           RW   G L+     R    +GG   + +     + D G+Y C A N+ G   SR A+L  
Sbjct: 91  RWSLNGTLINLGLDRRRRLSGGNLIISSLDR--YQDVGMYQCMAFNTAGAILSRRASLQF 148

Query: 104 AVLREEFRLEPESKQSA-QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG 162
           A L + F++   S  S  +G  VVL C  P  S +    W  N        D+R  +   
Sbjct: 149 AYL-DHFKVHTRSAVSVREGQGVVLLCGTPTSSGDLAYAWVFNEYPYFVQQDNRRFVSQQ 207

Query: 163 -GNLVIQDARQTDAGRYQCIARNAA--GTRESAIATLKIHI-------KPYL-ITGPEDV 211
            GNL I     +D G Y C+  N+   G  +S+   L +         +P + +  P++V
Sbjct: 208 TGNLYIAKVEPSDVGNYTCVVTNSVTKGKVQSSPTALILRTDGMMGEYEPKIEVNFPDNV 267

Query: 212 VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV-LDDGSLRLDNVILADEGEY 270
            A  GS+VT +C   G+P+P++ W+R A G   P  +VK+   +  L + +    D G Y
Sbjct: 268 SAARGSTVTLECFALGNPVPEITWKR-ANGVPFP-SKVKMKYSNAVLEIPSFQQDDTGGY 325

Query: 271 SCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
            C AEN +G   A+G L  Y  P    +     +       + C A G+P+P+  W   G
Sbjct: 326 ECVAENRMGKNMATGRLAFYAKPQWIQAVKDTALAIEERLHWECRANGKPKPSYAWLKNG 385

Query: 331 NRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT 390
            + +     S D+     V DGV  L++     +D+     C A N  G  +   +L V 
Sbjct: 386 QQLL-----SGDRI---TVEDGV--LSVPALALSDA-GMYQCVAENKHGVIYFVAELMVL 434

Query: 391 SDDDRPPPIITNGPSNQTLPIKS--MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN 448
           +     PP  T       L  K+       C     P   I W      +  N R  +++
Sbjct: 435 AS----PPDFTGNLLRALLKAKAGTTVTLECKPQAYPVASILWKKGNLPIHINDRITLSS 490

Query: 449 DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
           DGTL L ++ KSD+G YTC A +R G    +G LLV  P
Sbjct: 491 DGTLRLANVSKSDAGGYTCFARNRFGMSSTTGRLLVTDP 529



 Score =  142 bits (344), Expect = 5e-32
 Identities = 149/544 (27%), Positives = 225/544 (41%), Gaps = 63/544 (11%)

Query: 78  SDAGVYWCEATNSY--GTARSRNATLHV---AVLRE-EFRLE---PESKQSAQGDTVVLE 128
           SD G Y C  TNS   G  +S    L +    ++ E E ++E   P++  +A+G TV LE
Sbjct: 219 SDVGNYTCVVTNSVTKGKVQSSPTALILRTDGMMGEYEPKIEVNFPDNVSAARGSTVTLE 278

Query: 129 CLPPRGSPEPNVYWKK-NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
           C    G+P P + WK+ NG  + F    +M       L I   +Q D G Y+C+A N  G
Sbjct: 279 CFA-LGNPVPEITWKRANG--VPFPSKVKMKY-SNAVLEIPSFQQDDTGGYECVAENRMG 334

Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
            +  A   L  + KP  I   +D        + ++CR  G P P   W ++  G  +  G
Sbjct: 335 -KNMATGRLAFYAKPQWIQAVKDTALAIEERLHWECRANGKPKPSYAWLKN--GQQLLSG 391

Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-DPPSI--NLSPNSVNV 304
               ++DG L +  + L+D G Y C AEN  G +     L V   PP    NL    +  
Sbjct: 392 DRITVEDGVLSVPALALSDAGMYQCVAENKHGVIYFVAELMVLASPPDFTGNLLRALLKA 451

Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
           ++G      C     P  ++ W  +GN     P    D+   T   DG   L + +  K+
Sbjct: 452 KAGTTVTLECKPQAYPVASILWK-KGN----LPIHINDRI--TLSSDGT--LRLANVSKS 502

Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
           D+     C A N  G S   G+L VT      P  IT GP++  + +    V PC     
Sbjct: 503 DAGG-YTCFARNRFGMSSTTGRLLVTD-----PTRITQGPADMEIIVGESIVLPCQVASD 556

Query: 425 P--EPIIAWYFEGEALIQN--HRRNV--TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVW 478
           P  +   +W F G+ + +   H   V     G L+++++    +G Y CV  +       
Sbjct: 557 PVLDVSFSWAFNGQLIAKGDGHFELVGGRTAGDLMIRNIQLYHAGKYICVVDTDVESLSA 616

Query: 479 SGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGY 538
              L+V  P                P PP       VTD++  L+WS+    G S I+ Y
Sbjct: 617 VAILIVKGP----------------PSPPDSVTVEEVTDSTAQLAWSRGRDNG-SPIVNY 659

Query: 539 QVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
            V+  +  T+       N+   ++    +  T   V  L   + Y F V   NS G+  P
Sbjct: 660 FVQTRTPFTVGWQRV--NTVPEIIDGNTLTAT---VVDLNAWVEYEFRVLARNSVGVGEP 714

Query: 599 SPVS 602
           SPVS
Sbjct: 715 SPVS 718



 Score =  113 bits (272), Expect = 3e-23
 Identities = 97/322 (30%), Positives = 141/322 (43%), Gaps = 25/322 (7%)

Query: 18  PLDVTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAGGLFFLRATHGRV 76
           P +V+ AR    TL C A G+P P I W +  GV   S        A     +       
Sbjct: 264 PDNVSAARGSTVTLECFALGNPVPEITWKRANGVPFPSKVKMKYSNA-----VLEIPSFQ 318

Query: 77  HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
             D G Y C A N  G   +       A  + ++    +    A  + +  EC    G P
Sbjct: 319 QDDTGGYECVAENRMGKNMATGRLAFYA--KPQWIQAVKDTALAIEERLHWECRA-NGKP 375

Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
           +P+  W KNGQ LL  GD R+  V+ G L +     +DAG YQC+A N  G     +A L
Sbjct: 376 KPSYAWLKNGQQLL-SGD-RI-TVEDGVLSVPALALSDAGMYQCVAENKHGVIYF-VAEL 431

Query: 197 KIHIKPYLITGP---EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL---GRVK 250
            +   P   TG      + A+ G++VT +C+    P+  +LW++    GN+P+    R+ 
Sbjct: 432 MVLASPPDFTGNLLRALLKAKAGTTVTLECKPQAYPVASILWKK----GNLPIHINDRIT 487

Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310
           +  DG+LRL NV  +D G Y+C A N  G  S +G L V DP  I   P  + +  G   
Sbjct: 488 LSSDGTLRLANVSKSDAGGYTCFARNRFGMSSTTGRLLVTDPTRITQGPADMEIIVGESI 547

Query: 311 RFTCTATGRP--EPTMFWSVEG 330
              C     P  + +  W+  G
Sbjct: 548 VLPCQVASDPVLDVSFSWAFNG 569



 Score =  107 bits (258), Expect = 1e-21
 Identities = 92/301 (30%), Positives = 130/301 (43%), Gaps = 20/301 (6%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P  I+   D  +A  +     CRA G P P+  W K G  ++S     I    G+  + A
Sbjct: 348 PQWIQAVKDTALAIEERLHWECRANGKPKPSYAWLKNGQQLLSGDR--ITVEDGVLSVPA 405

Query: 72  THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEF--RLEPESKQSAQGDTVVLEC 129
                 SDAG+Y C A N +G      A L V     +F   L     ++  G TV LEC
Sbjct: 406 L---ALSDAGMYQCVAENKHGVIYF-VAELMVLASPPDFTGNLLRALLKAKAGTTVTLEC 461

Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
             P+  P  ++ WKK    L    + R+ L   G L + +  ++DAG Y C ARN  G  
Sbjct: 462 -KPQAYPVASILWKKG--NLPIHINDRITLSSDGTLRLANVSKSDAGGYTCFARNRFG-M 517

Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-----GNM 244
            S    L +     +  GP D+    G S+   C+V  DP+ DV +  +  G     G+ 
Sbjct: 518 SSTTGRLLVTDPTRITQGPADMEIIVGESIVLPCQVASDPVLDVSFSWAFNGQLIAKGDG 577

Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
               V     G L + N+ L   G+Y C  +  V ++SA   L V  PPS    P+SV V
Sbjct: 578 HFELVGGRTAGDLMIRNIQLYHAGKYICVVDTDVESLSAVAILIVKGPPS---PPDSVTV 634

Query: 305 E 305
           E
Sbjct: 635 E 635


>UniRef50_A4JYE0 Cluster: CDNA, clone cssl:d0205; n=2; Danio
           rerio|Rep: CDNA, clone cssl:d0205 - Danio rerio
           (Zebrafish) (Brachydanio rerio)
          Length = 744

 Score =  144 bits (348), Expect = 2e-32
 Identities = 151/555 (27%), Positives = 235/555 (42%), Gaps = 52/555 (9%)

Query: 10  EAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGL 66
           + P I++Q L D  V       + C A G+P P  +W + G    V  D   ++    G 
Sbjct: 40  QPPTIVKQSLKDYIVDPRDNIIIECEAKGNPVPTFQWRRNGKFFNVGKDPRVTMRSRSGT 99

Query: 67  FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV--LREEFRLEPESKQSAQGDT 124
             +R++ G+     G Y C A+N+ GTA S    L V+   L  +  LEP + +  +G  
Sbjct: 100 LEIRSS-GKPEDYEGEYQCFASNNLGTAISNKILLRVSKSPLWPKEVLEPVTVR--EGSP 156

Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIAR 183
           +VL C PP G P P  +W  +   +    D R+ +   G+L   +    DA   Y C AR
Sbjct: 157 LVLACNPPPGLPPPETFW-MDSFIMPIAQDRRVSMGLNGDLFFSNVLAKDAKTDYSCNAR 215

Query: 184 --NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVT----------FQCRVGGDPLP 231
                  ++    TLK+     +       ++ TG S T           +C   G P P
Sbjct: 216 FEFTHTIQQKNPYTLKVQTMRNIPETQPTFLSPTGLSSTKMVLRGEELLLECIAAGVPTP 275

Query: 232 DVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290
            + W  S  GG++P  +V++ + D +LR+ NV   D G Y+C A N +G++  +  + V 
Sbjct: 276 TITW--SKRGGDLPTKKVRIGNFDKTLRILNVSEEDIGSYTCMASNRIGSIRHTVEVQVK 333

Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR-TIIFPGMSRDKYHATAV 349
             P     P ++ +      R  C A G P+PT+ W V G       P  +R     T +
Sbjct: 334 AAPFWLEKPINLVLAPDESGRLVCRANGSPKPTIQWLVNGEPIESSLPNPNRRVLDDTII 393

Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409
           F         +T + +S     C+A N  G       ++V    D  P ++  GP NQ +
Sbjct: 394 F---------ETVQFESSAVYQCNASNEHGYLLANAFVSVL---DMAPRML--GPKNQLI 439

Query: 410 PI--KSMAVFPCTAICTPEPIIAWYFE--GEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465
            +   +     C    +P P++ W+    G  L   H R + ++GTL +K     D GTY
Sbjct: 440 KVIENNRTFLECPFFGSPLPLLRWFKNGLGSGLDGGHYR-LYHNGTLEIKQAQTEDQGTY 498

Query: 466 TCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVT-DTSV--TL 522
           TCVAS   GK      L V  P        RA +  + P   T      V  D S+  T+
Sbjct: 499 TCVASIILGKMENQVRLEVKEP----TRIVRAPEHKTEPRGTTVRFDCRVKHDPSLPATV 554

Query: 523 SWSQNNKIGSSSILG 537
           +W ++ K  S S +G
Sbjct: 555 TWLKDEKPLSFSWIG 569



 Score =  116 bits (278), Expect = 5e-24
 Identities = 94/301 (31%), Positives = 144/301 (47%), Gaps = 19/301 (6%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS---DTHRSILPAGGLF 67
           AP+ +E+P+++ +A  +   L CRA GSP P I+W   G  + S   + +R +L    +F
Sbjct: 335 APFWLEKPINLVLAPDESGRLVCRANGSPKPTIQWLVNGEPIESSLPNPNRRVLDDTIIF 394

Query: 68  FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTV 125
                       + VY C A+N +G   + NA + V  +     L P+++  +  + +  
Sbjct: 395 -----ETVQFESSAVYQCNASNEHGYLLA-NAFVSVLDMAPRM-LGPKNQLIKVIENNRT 447

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
            LEC P  GSP P + W KNG     DG     L   G L I+ A+  D G Y C+A   
Sbjct: 448 FLEC-PFFGSPLPLLRWFKNGLGSGLDG-GHYRLYHNGTLEIKQAQTEDQGTYTCVASII 505

Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP-LP-DVLWRRSAGGGN 243
            G  E+ +  L++     ++  PE      G++V F CRV  DP LP  V W +     +
Sbjct: 506 LGKMENQV-RLEVKEPTRIVRAPEHKTEPRGTTVRFDCRVKHDPSLPATVTWLKDEKPLS 564

Query: 244 MP-LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
              +GR+K  DD SL + NV   D G Y+C A+  +   +AS  LTV +  S + S  S 
Sbjct: 565 FSWIGRLK-KDDESLTIYNVNPDDGGTYTCTAKTEIDEDTASARLTVTENDSSSASNRSA 623

Query: 303 N 303
           +
Sbjct: 624 S 624



 Score =  111 bits (266), Expect = 1e-22
 Identities = 145/603 (24%), Positives = 227/603 (37%), Gaps = 61/603 (10%)

Query: 21  VTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPAGG-LFFLRATHGRVHS 78
           VTV    P  L C    G P P   W    ++ ++   R  +   G LFF         +
Sbjct: 149 VTVREGSPLVLACNPPPGLPPPETFWMDSFIMPIAQDRRVSMGLNGDLFFSNVLAKDAKT 208

Query: 79  DAGVYWCEATNSYG-TARSRNA-TLHVAVLREEFRLEP---------ESKQSAQGDTVVL 127
           D   Y C A   +  T + +N  TL V  +R     +P          +K   +G+ ++L
Sbjct: 209 D---YSCNARFEFTHTIQQKNPYTLKVQTMRNIPETQPTFLSPTGLSSTKMVLRGEELLL 265

Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN----LVIQDARQTDAGRYQCIAR 183
           EC+   G P P + W K G      GD     V  GN    L I +  + D G Y C+A 
Sbjct: 266 ECIAA-GVPTPTITWSKRG------GDLPTKKVRIGNFDKTLRILNVSEEDIGSYTCMAS 318

Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-- 241
           N  G+    +  +++   P+ +  P ++V     S    CR  G P P + W  +     
Sbjct: 319 NRIGSIRHTVE-VQVKAAPFWLEKPINLVLAPDESGRLVCRANGSPKPTIQWLVNGEPIE 377

Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
            ++P    +VLDD ++  + V       Y C A N  G + A+ +++V D     L P +
Sbjct: 378 SSLPNPNRRVLDD-TIIFETVQFESSAVYQCNASNEHGYLLANAFVSVLDMAPRMLGPKN 436

Query: 302 --VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
             + V   N     C   G P P + W   G       G   D  H     +G   L I 
Sbjct: 437 QLIKVIENNRTFLECPFFGSPLPLLRWFKNGL------GSGLDGGHYRLYHNGT--LEIK 488

Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419
                D + T  C A    G    + +L V     + P  I   P ++T P  +   F C
Sbjct: 489 QAQTED-QGTYTCVASIILGKMENQVRLEV-----KEPTRIVRAPEHKTEPRGTTVRFDC 542

Query: 420 TAICTPE--PIIAWYFEGEALIQNH-RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476
                P     + W  + + L  +   R   +D +L + +++  D GTYTC A +   + 
Sbjct: 543 RVKHDPSLPATVTWLKDEKPLSFSWIGRLKKDDESLTIYNVNPDDGGTYTCTAKTEIDED 602

Query: 477 VWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSIL 536
             S  L V    N +      +  +  P PP      + +  SV L+W   N+  +S + 
Sbjct: 603 TASARLTVTE--NDSSSASNRSASAGRPDPPQDLELSDPSARSVRLTWVPGNE-NNSPVT 659

Query: 537 GYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
            + V+        G         W  ++      + V   L P + Y F V   N+ G S
Sbjct: 660 HFLVQFEEDRWEPGK--------WQNLSIYDWNLNSVNLQLSPFVNYQFRVIAINAVGQS 711

Query: 597 GPS 599
            PS
Sbjct: 712 QPS 714


>UniRef50_P32004 Cluster: Neural cell adhesion molecule L1
           precursor; n=68; Mammalia|Rep: Neural cell adhesion
           molecule L1 precursor - Homo sapiens (Human)
          Length = 1257

 Score =  143 bits (347), Expect = 2e-32
 Identities = 136/484 (28%), Positives = 202/484 (41%), Gaps = 37/484 (7%)

Query: 10  EAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL----PAG 64
           E P I EQ P  + V      +L C A G P    RW + GV         +     P  
Sbjct: 33  EPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHS 92

Query: 65  GLFFLRATHGR-VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
           G F +   +        G+Y C A+N  GTA S    L      +  +   +  +  +G+
Sbjct: 93  GSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGE 152

Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIA 182
           +VVL C PP  +    +YW  N + L    D R+ +   GNL   +   +D    Y C A
Sbjct: 153 SVVLPCNPPPSAEPLRIYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA 211

Query: 183 RNAAGTR-----ESAIATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDP 229
            +  GTR     E     +K     I  KP L+        +VA  G  +  +C   G P
Sbjct: 212 -HFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 270

Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
            P + W R +G   MP  RV   +   +L+L  V   D+GEY C AENS+G+   + Y+T
Sbjct: 271 TPTIKWLRPSGP--MPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVT 328

Query: 289 VYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
           V   P     P S     G  AR  C   GRP+P + W + G   I    +++D+ +   
Sbjct: 329 VEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--R 383

Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408
           +  G  +L  ++   +D+  T  C A N  G       + V      P  I+T       
Sbjct: 384 IQRGALIL--SNVQPSDTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYM 437

Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
               S A   C A   P P + W  E G  ++Q+ R     +GTL ++DL  +D+G Y C
Sbjct: 438 AVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFC 497

Query: 468 VASS 471
           +A++
Sbjct: 498 LAAN 501



 Score =  127 bits (306), Expect = 2e-27
 Identities = 159/609 (26%), Positives = 239/609 (39%), Gaps = 71/609 (11%)

Query: 21  VTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGG-LFFLRATHGRVHS 78
           V V   +   L C    S  P  I W    +L +    R  +   G L+F        HS
Sbjct: 146 VEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHS 205

Query: 79  DAGVYWCEA--TNSYGTARSRNATLHVAVL-----REEFRLEPESKQS----AQGDTVVL 127
           D   Y C A    +    +     L V        R+   L P +  S     QG  +VL
Sbjct: 206 D---YICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVL 262

Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
           EC+   G P P + W +    +    D   +      L +    + D G Y+C+A N+ G
Sbjct: 263 ECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLG 319

Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSAGGGNMPL 246
           +   A   + +   PY +  P+  +   G +    C+V G P P+V WR        +  
Sbjct: 320 SARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK 378

Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
            +   +  G+L L NV  +D     CEA N  G + A+ Y+ V   P+  L+ ++    +
Sbjct: 379 DQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMA 438

Query: 307 --GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
             G+ A   C A G P P++ W  E   T++      +++   A  +G   L I D   N
Sbjct: 439 VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LGIRDLQAN 490

Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
           D+     C A N   +  +   L V          IT GP +      S   F C A   
Sbjct: 491 DT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTFTCQASFD 544

Query: 425 P--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
           P  +P I W  +G  L  + +  +    DG LV+  LD SD G Y+CVAS+         
Sbjct: 545 PSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRA 604

Query: 481 ALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKIGSSSILG 537
            LLV               V S PGP  + +    H +T + V +SWS      ++ I  
Sbjct: 605 QLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED-HNAPIEK 647

Query: 538 YQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
           Y +E   +E       P     W  + +   +QT   +K L P + Y F V   N +G  
Sbjct: 648 YDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPG 698

Query: 597 GPSPVSDSV 605
            PSPVS++V
Sbjct: 699 EPSPVSETV 707



 Score =  116 bits (278), Expect = 5e-24
 Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)

Query: 5   YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
           YVT   APY + +P        + A L+C+  G P P + W   G+ V  ++   +  + 
Sbjct: 326 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 385

Query: 63  AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
            G L           SD  V  CEA N +G   + NA ++V  L  +    + ++  + Q
Sbjct: 386 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 440

Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
           G T  L C    G+P P+V W  ++G T+L   D R      G L I+D +  D GRY C
Sbjct: 441 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 497

Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
           +A N      + +A LK+     +  GP   + + GS VTF C+   DP   P + W R 
Sbjct: 498 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 555

Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
            G     LG      ++DG L + ++  +D+G YSC A   +  V +   L V   P
Sbjct: 556 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 612



 Score = 40.7 bits (91), Expect = 0.24
 Identities = 33/135 (24%), Positives = 57/135 (42%), Gaps = 6/135 (4%)

Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
           +++   +  YE  +     + +G      +  + +D P   P    + ILN++ V +KW 
Sbjct: 775 VSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWR 834

Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH-----QATSLIMTNLTSGVSYSV 808
           P +L    G + GYNV   W +    K         H       TS+I++ L    SY +
Sbjct: 835 PVDLAQVKGHLRGYNVTY-WREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHL 893

Query: 809 QIAAETIIGLGPFSQ 823
           ++ A    G GP S+
Sbjct: 894 EVQAFNGRGSGPASE 908


>UniRef50_UPI0000E815E6 Cluster: PREDICTED: similar to
           roundabout-like protein 4; n=2; Gallus gallus|Rep:
           PREDICTED: similar to roundabout-like protein 4 - Gallus
           gallus
          Length = 992

 Score =  143 bits (346), Expect = 3e-32
 Identities = 77/190 (40%), Positives = 106/190 (55%), Gaps = 4/190 (2%)

Query: 100 TLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL 159
           T   A LR+ FRL+P       G  + L+C+PP G PEP V W+K+G  L   G    H 
Sbjct: 35  TQRPAELRDNFRLQPGDLVVMAGQALELDCVPPAGQPEPRVTWRKDGVALRLAGGR--HQ 92

Query: 160 VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSV 219
           +  G L +  AR++DAG Y C+A NAAG R S  A + I  KP ++  P DV A  GS+V
Sbjct: 93  LTRGKLWVASARRSDAGVYVCVAANAAGERHSRGAHVTILEKPVIVRRPSDVTAVAGSTV 152

Query: 220 TFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279
              C   GDP P V W + +  G++P GR +V  + +LRL  V  AD G Y C A++ +G
Sbjct: 153 ELSCGAQGDPAPRVQWHKES--GDLPWGRHEVDQEHTLRLYAVTAADGGAYVCTAQSQLG 210

Query: 280 AVSASGYLTV 289
           + +A+  L V
Sbjct: 211 STAATARLRV 220



 Score = 73.7 bits (173), Expect = 3e-11
 Identities = 61/193 (31%), Positives = 81/193 (41%), Gaps = 15/193 (7%)

Query: 17  QPLDVTVARHQPATLNC-RAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75
           QP D+ V   Q   L+C    G P P + W K GV +     R  L  G L+   A    
Sbjct: 48  QPGDLVVMAGQALELDCVPPAGQPEPRVTWRKDGVALRLAGGRHQLTRGKLWVASARR-- 105

Query: 76  VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRG 134
             SDAGVY C A N+ G   SR A  HV +L +   +  P    +  G TV L C   +G
Sbjct: 106 --SDAGVYVCVAANAAGERHSRGA--HVTILEKPVIVRRPSDVTAVAGSTVELSC-GAQG 160

Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194
            P P V W K    L +    R  +     L +      D G Y C A++  G   S  A
Sbjct: 161 DPAPRVQWHKESGDLPW---GRHEVDQEHTLRLYAVTAADGGAYVCTAQSQLG---STAA 214

Query: 195 TLKIHIKPYLITG 207
           T ++ ++  L  G
Sbjct: 215 TARLRVEGQLPAG 227



 Score = 62.1 bits (144), Expect = 9e-08
 Identities = 40/147 (27%), Positives = 63/147 (42%), Gaps = 3/147 (2%)

Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC-RVGGDPLPDVLWRRSAGGGN 243
           + G  ES        ++      P D+V   G ++   C    G P P V WR+      
Sbjct: 26  SGGDMESPTTQRPAELRDNFRLQPGDLVVMAGQALELDCVPPAGQPEPRVTWRKDGVALR 85

Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASG-YLTVYDPPSINLSPNSV 302
           +  GR + L  G L + +   +D G Y C A N+ G   + G ++T+ + P I   P+ V
Sbjct: 86  LAGGRHQ-LTRGKLWVASARRSDAGVYVCVAANAAGERHSRGAHVTILEKPVIVRRPSDV 144

Query: 303 NVESGNVARFTCTATGRPEPTMFWSVE 329
              +G+    +C A G P P + W  E
Sbjct: 145 TAVAGSTVELSCGAQGDPAPRVQWHKE 171



 Score = 53.6 bits (123), Expect = 3e-05
 Identities = 50/196 (25%), Positives = 75/196 (38%), Gaps = 16/196 (8%)

Query: 294 SINLSPNSVNVESGNVARFTCTA-TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
           +  L P  + V +G      C    G+PEP + W  +G    +  G    ++  T     
Sbjct: 44  NFRLQPGDLVVMAGQALELDCVPPAGQPEPRVTWRKDGVALRLAGG----RHQLTR---- 95

Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
              L +    ++D+    VC A N AG    RG      +     P+I   PS+ T    
Sbjct: 96  -GKLWVASARRSDA-GVYVCVAANAAGERHSRGAHVTILEK----PVIVRRPSDVTAVAG 149

Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
           S     C A   P P + W+ E   L    R  V  + TL L  +  +D G Y C A S+
Sbjct: 150 STVELSCGAQGDPAPRVQWHKESGDLPWG-RHEVDQEHTLRLYAVTAADGGAYVCTAQSQ 208

Query: 473 HGKYVWSGALLVDSPI 488
            G    +  L V+  +
Sbjct: 209 LGSTAATARLRVEGQL 224



 Score = 49.6 bits (113), Expect = 5e-04
 Identities = 54/198 (27%), Positives = 85/198 (42%), Gaps = 14/198 (7%)

Query: 627 RNNILTDHIVELIEATPIDSK-TIKLMWEILNFYYL-EGLFIYFRPLDNITIEYEMKTIL 684
           R N+L   + +L   T + +  T+ L W +L      EG  + +R L   +  +  + + 
Sbjct: 233 RRNLLAVQL-QLDNGTALPTNATVWLRWRMLTPGPAPEGYVVLYRCLLPASTAWSQQDV- 290

Query: 685 HSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPP--INIEMFI 742
              ++S   I +L++  +YEF + P+    +G  SNS      ++VP   P  + +    
Sbjct: 291 -GRELSTI-IPALKRGYQYEFKVRPYAGGTQGLDSNSWHLWIPEEVPSAAPQRVTVGQAA 348

Query: 743 LNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTS 802
               TV + W PP     NGII GY V   W        +   N TV   T  + T L  
Sbjct: 349 PGNGTVIVSWEPPPPDAHNGIIRGYQV---W--SLGEGWLQPTNHTVDGGTRRLETLLHG 403

Query: 803 -GVSYSVQIAAETIIGLG 819
            G  Y +Q+AA    GLG
Sbjct: 404 PGARYCIQVAAFNGAGLG 421



 Score = 41.9 bits (94), Expect = 0.10
 Identities = 17/43 (39%), Positives = 25/43 (58%)

Query: 5   YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK 47
           +VT  E P I+ +P DVT        L+C A G P+P ++W+K
Sbjct: 128 HVTILEKPVIVRRPSDVTAVAGSTVELSCGAQGDPAPRVQWHK 170



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 6/106 (5%)

Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA--L 482
           PEP + W  +G AL     R+    G L +    +SD+G Y CVA++  G+    GA   
Sbjct: 71  PEPRVTWRKDGVALRLAGGRHQLTRGKLWVASARRSDAGVYVCVAANAAGERHSRGAHVT 130

Query: 483 LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNN 528
           +++ P+       R +DV+++ G   +       D +  + W + +
Sbjct: 131 ILEKPVIVR----RPSDVTAVAGSTVELSCGAQGDPAPRVQWHKES 172


>UniRef50_P98160 Cluster: Basement membrane-specific heparan sulfate
            proteoglycan core protein precursor; n=26; Eumetazoa|Rep:
            Basement membrane-specific heparan sulfate proteoglycan
            core protein precursor - Homo sapiens (Human)
          Length = 4391

 Score =  143 bits (346), Expect = 3e-32
 Identities = 151/515 (29%), Positives = 212/515 (41%), Gaps = 61/515 (11%)

Query: 11   APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
            AP +  +  ++TV     ATL C A GSP+P I W K    +    HR  L    L   R
Sbjct: 3211 APQVQAEEAELTVEAGHTATLRCSATGSPAPTIHWSKLRSPLPWQ-HR--LEGDTLIIPR 3267

Query: 71   ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
                    D+G Y C AT+  G A +    LHV        + PE      G+TV L+CL
Sbjct: 3268 VAQ----QDSGQYICNATSPAGHAEA-TIILHVESPPYATTV-PEHASVQAGETVQLQCL 3321

Query: 131  PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
               G+P     W + G +L     +R  L     L  + A   D+GRY+C   N  G+ E
Sbjct: 3322 A-HGTPPLTFQWSRVGSSLPGRATARNEL-----LHFERAAPEDSGRYRCRVTNKVGSAE 3375

Query: 191  SAIATLKIHIKPYLITG--------------PEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
             A A L +   P  +                P+      G+SV F C V  D    + W 
Sbjct: 3376 -AFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWF 3434

Query: 237  RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS-- 294
            +   GG +P G    + DG LR+ N+  + +G Y C+A    G   AS  L +   PS  
Sbjct: 3435 KE--GGQLPPGHS--VQDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVL 3490

Query: 295  INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
            IN+  +   V  G+   F C A G P+P + WS  G    + PG+ +           V 
Sbjct: 3491 INIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGH--LRPGIVQSG-------GVVR 3541

Query: 355  VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
            +  +   D    R    C+A N AG++     L V +     P I  + P    +P  S 
Sbjct: 3542 IAHVELADAGQYR----CTATNAAGTTQSHVLLLVQA----LPQI--SMPQEVRVPAGSA 3591

Query: 415  AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
            AVFPC A   P P I+W     +L  + R     +  L+L  +   D+GTY C A++R G
Sbjct: 3592 AVFPCIASGYPTPDISWSKLDGSLPPDSR---LENNMLMLPSVRPQDAGTYVCTATNRQG 3648

Query: 475  KYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTK 509
            K      L V   + P   +F     S LP P  K
Sbjct: 3649 KVKAFAHLQVPERVVP---YFTQTPYSFLPLPTIK 3680



 Score =  130 bits (313), Expect = 3e-28
 Identities = 125/488 (25%), Positives = 192/488 (39%), Gaps = 35/488 (7%)

Query: 11   APYIIEQPLDVTVARHQPATLNCRAGGSPSP-AIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            +P I   P   TV + Q A+  C      +P ++ W      +  + H  I P G +  +
Sbjct: 3021 SPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNVH--ISPNGSIITI 3078

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQ-GDTVVL 127
              T    H   G Y C A+N+YG A+S  N ++H         + PE     + G  V L
Sbjct: 3079 VGTRPSNH---GTYRCVASNAYGVAQSVVNLSVHGP---PTVSVLPEGPVWVKVGKAVTL 3132

Query: 128  ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAA 186
            EC+   G P  +  W +   T          L+D    L I  A+ +DAG Y C+A+NA 
Sbjct: 3133 ECVSA-GEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNAL 3191

Query: 187  GTRESAIATL-----KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
            GT +  +  +          P +     ++  + G + T +C   G P P + W +    
Sbjct: 3192 GTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHWSKLRS- 3250

Query: 242  GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
               PL     L+  +L +  V   D G+Y C A +  G   A+  L V  PP     P  
Sbjct: 3251 ---PLPWQHRLEGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVESPPYATTVPEH 3307

Query: 302  VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
             +V++G   +  C A G P  T  WS  G+     PG +  + +    F+        D+
Sbjct: 3308 ASVQAGETVQLQCLAHGTPPLTFQWSRVGSS---LPGRATAR-NELLHFERAAP---EDS 3360

Query: 362  DKNDSRNTIVCSAVNYAGSSFVR---GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
             +   R T    +        V+   G L  TS      P +   P  +T  I +   F 
Sbjct: 3361 GRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFH 3420

Query: 419  CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVW 478
            C         + W+ EG  L   H      DG L +++LD+S  GTY C A    GK   
Sbjct: 3421 CAVPSDRGTQLRWFKEGGQLPPGHS---VQDGVLRIQNLDQSCQGTYICQAHGPWGKAQA 3477

Query: 479  SGALLVDS 486
            S  L++ +
Sbjct: 3478 SAQLVIQA 3485



 Score =  118 bits (283), Expect = 1e-24
 Identities = 119/479 (24%), Positives = 182/479 (37%), Gaps = 38/479 (7%)

Query: 8    SGEAPYIIE-QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66
            + +AP ++E  P    V +    +L C+  GSP     W +     V    +       L
Sbjct: 1672 TNQAPLVVEVHPARSIVPQGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGSEL 1731

Query: 67   FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GD 123
             F         SDAGVY C   N + +  SR   L      +   +  E ++S     G 
Sbjct: 1732 HFPSVQP----SDAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGA 1787

Query: 124  TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIA 182
             V   C     SP   + W     T L +G      +D  G L I++ + +DAG Y C  
Sbjct: 1788 DVTFICTAKSKSPAYTLVW-----TRLHNGKLPTRAMDFNGILTIRNVQLSDAGTYVCTG 1842

Query: 183  RNAAGTRESAIATLKIHIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
             N     +   ATL +        P +   P  +  Q G    F+C   G P P + W  
Sbjct: 1843 SNMF-AMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW-T 1900

Query: 238  SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY--DPPSI 295
               GG +P  + ++   G LRL  V   D+ +Y C A +S G   A   L V+    P +
Sbjct: 1901 GGPGGQLP-AKAQI-HGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRV 1958

Query: 296  NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
             +SP    V +G   R  C A G P  T+ W  EG      P  +R +    A    + +
Sbjct: 1959 QVSPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGS---LPPQARSERTDIAT---LLI 2012

Query: 356  LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
              I   D        +C A + AG++  R ++ V S  D  PP +    S+ ++      
Sbjct: 2013 PAITTAD----AGFYLCVATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTL 2068

Query: 416  VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
               C    +    + WY  G +L  + +    +   L L  +  +DSG Y C   +  G
Sbjct: 2069 DLNCVVAGSAHAQVTWYRRGGSLPPHTQ---VHGSRLRLPQVSPADSGEYVCRVENGSG 2124



 Score =  108 bits (260), Expect = 8e-22
 Identities = 130/482 (26%), Positives = 184/482 (38%), Gaps = 52/482 (10%)

Query: 11   APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
            AP +   P  +TV   Q A   C A GSP+P + W  GG          I   GG+  L 
Sbjct: 1865 APVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW-TGGPGGQLPAKAQI--HGGILRLP 1921

Query: 71   ATHGRVHSDAGVYWCEATNSYGTARSRNATLHV-AVLREEFRLEPESKQSAQGDTVVLEC 129
            A      +D   Y C A +S G   +R A LHV        ++ PE  Q   G TV L C
Sbjct: 1922 AVE---PTDQAQYLCRAHSSAGQQVAR-AVLHVHGGGGPRVQVSPERTQVHAGRTVRLYC 1977

Query: 130  LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
                G P   + W+K G +L     +R    D   L+I      DAG Y C+A + AGT 
Sbjct: 1978 -RAAGVPSATITWRKEGGSL--PPQARSERTDIATLLIPAITTADAGFYLCVATSPAGTA 2034

Query: 190  ESAIATLKIHIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
            ++ I  + +        P  I      V + G ++   C V G     V W R   GG++
Sbjct: 2035 QARIQVVVLSASDASPPPVKIESSSPSVTE-GQTLDLNCVVAGSAHAQVTWYRR--GGSL 2091

Query: 245  PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV----YDPPS------ 294
            P    +V     LRL  V  AD GEY C  EN  G   AS  ++V    +  PS      
Sbjct: 2092 P-PHTQV-HGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPG 2149

Query: 295  ----INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
                I + P+S +V  G      C   G+    + W   G      P  +R + H     
Sbjct: 2150 STRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGS---LP--ARHQTHG---- 2200

Query: 351  DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV-TSDDDRPPPIITNGPSNQTL 409
               ++L ++     DS    VC  V  +G       +T+  S    P P +    S+ T+
Sbjct: 2201 ---SLLRLHQVTPADS-GEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTV 2256

Query: 410  PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
                     C         + WY  G +L   H+        L +     +D+G Y C A
Sbjct: 2257 AEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQ---VRGSRLYIFQASPADAGQYVCRA 2313

Query: 470  SS 471
            S+
Sbjct: 2314 SN 2315



 Score =  103 bits (246), Expect = 4e-20
 Identities = 125/496 (25%), Positives = 194/496 (39%), Gaps = 64/496 (12%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
            V  G  P +  +    TVA  Q   L+C   G     + WYK G  + +   R  +    
Sbjct: 2239 VIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPA---RHQVRGSR 2295

Query: 66   LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNAT-------LHVAVLREEFRLEPESKQ 118
            L+  +A+     +DAG Y C A+N    + +   T        + A   +  R+EP S Q
Sbjct: 2296 LYIFQASP----ADAGQYVCRASNGMEASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQ 2351

Query: 119  SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY 178
             A+G T+ L C+ P G     V W K G +L        H   G  L +  A   D+G Y
Sbjct: 2352 VAEGQTLDLNCVVP-GQSHAQVTWHKRGGSL-----PVRHQTHGSLLRLYQASPADSGEY 2405

Query: 179  QC-IARNAAGTRESAIATLK-------IHIKPYL-ITGPEDVVAQTGSSVTFQCRVGGDP 229
             C +  ++     S + T++       + + P + I      VA+ G ++   C V G  
Sbjct: 2406 VCRVLGSSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAE-GQTLDLNCLVAGQA 2464

Query: 230  LPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
               V W +   GG++P  R +V     LRL  V  AD GEY C    S G   AS  +T+
Sbjct: 2465 HAQVTWHKR--GGSLP-ARHQV-HGSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTI 2520

Query: 290  YDPPS----------INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG----NRTII 335
                S          + +  +S ++ +G+     C    +   T+ W   G    +R  I
Sbjct: 2521 QQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPSRHQI 2580

Query: 336  FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395
                 R     T    G  V  +  ++   SR T +   +  +GSS V         +  
Sbjct: 2581 VGSRLRIP-QVTPADSGEYVCHV--SNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESS 2637

Query: 396  PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLK 455
             P ++      QTL +       C     P+ II WY  G +L   H+   T+   L L 
Sbjct: 2638 SPTVV----EGQTLDLN------CVVARQPQAIITWYKRGGSLPSRHQ---THGSHLRLH 2684

Query: 456  DLDKSDSGTYTCVASS 471
             +  +DSG Y C A++
Sbjct: 2685 QMSVADSGEYVCRANN 2700



 Score = 96.3 bits (229), Expect = 4e-18
 Identities = 126/512 (24%), Positives = 193/512 (37%), Gaps = 60/512 (11%)

Query: 9    GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
            G  P +  +     VA  Q   LNC   G     + W+K G  + +   R  +    L  
Sbjct: 2434 GVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPA---RHQVHGSRLRL 2490

Query: 69   LRATHGRVHSDAGVYWCEATNSYGTARS--------RNATLHVAVLREEFRLEPESKQSA 120
            L+ T     +D+G Y C    S GT  +        R +  H   +    R+E  S   A
Sbjct: 2491 LQVTP----ADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLA 2546

Query: 121  QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
             G T+ L CL    +P   + W K G +L     SR H + G  L I      D+G Y C
Sbjct: 2547 NGHTLDLNCLVASQAPH-TITWYKRGGSL----PSR-HQIVGSRLRIPQVTPADSGEYVC 2600

Query: 181  IARNAAGTRE-SAIATLK----IHI----KPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231
               N AG+RE S I T++     H+     P  I      V + G ++   C V   P  
Sbjct: 2601 HVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVE-GQTLDLNCVVARQPQA 2659

Query: 232  DVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV-- 289
             + W +   GG++P  R +      LRL  + +AD GEY C A N++ A+ AS  ++V  
Sbjct: 2660 IITWYKR--GGSLP-SRHQT-HGSHLRLHQMSVADSGEYVCRANNNIDALEASIVISVSP 2715

Query: 290  -YDPPS-------INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF---PG 338
                PS       I +  +S +V  G      C   G+    + W   G          G
Sbjct: 2716 SAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQTRG 2775

Query: 339  MSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398
                 +H +    G  V  +  +      + +V   +  +GSS V       +   R  P
Sbjct: 2776 SRLRLHHVSPADSGEYVCRVMGSSGPLEASVLV--TIEASGSSAVHVPAPGGAPPIRIEP 2833

Query: 399  IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLD 458
              +     QTL +K      C         + W+  G  L   H+    +   L L  + 
Sbjct: 2834 SSSRVAEGQTLDLK------CVVPGQAHAQVTWHKRGGNLPARHQ---VHGPLLRLNQVS 2884

Query: 459  KSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
             +DSG Y+C  +   G  + +  L+   P +P
Sbjct: 2885 PADSGEYSCQVTGSSGT-LEASVLVTIEPSSP 2915



 Score = 94.3 bits (224), Expect = 2e-17
 Identities = 134/512 (26%), Positives = 193/512 (37%), Gaps = 79/512 (15%)

Query: 5    YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS--DTHRSILP 62
            +V S   P  IE     TV   Q   LNC     P   I WYK G  + S   TH S L 
Sbjct: 2624 HVPSVSPPIRIESS-SPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPSRHQTHGSHL- 2681

Query: 63   AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE---------FRLE 113
                      H    +D+G Y C A N+   A   +  + V+               R+E
Sbjct: 2682 --------RLHQMSVADSGEYVCRANNNID-ALEASIVISVSPSAGSPSAPGSSMPIRIE 2732

Query: 114  PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT 173
              S   A+G+T+ L C+ P G     V W K G +L        H   G  L +      
Sbjct: 2733 SSSSHVAEGETLDLNCVVP-GQAHAQVTWHKRGGSL-----PSHHQTRGSRLRLHHVSPA 2786

Query: 174  DAGRYQCIARNAAGTRE-SAIATLK------IHIK-----PYLITGPEDVVAQTGSSVTF 221
            D+G Y C    ++G  E S + T++      +H+      P +   P       G ++  
Sbjct: 2787 DSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDL 2846

Query: 222  QCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281
            +C V G     V W +   GGN+P  R +V     LRL+ V  AD GEYSC+   S G +
Sbjct: 2847 KCVVPGQAHAQVTWHKR--GGNLP-ARHQV-HGPLLRLNQVSPADSGEYSCQVTGSSGTL 2902

Query: 282  SASGYLTVYDPPS------------INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVE 329
             AS  +T+ +P S            I +  +S +V  G      C   G+    + W   
Sbjct: 2903 EASVLVTI-EPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKR 2961

Query: 330  GNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389
            G      P  +R + H +        L ++     DS    VC A +  G        TV
Sbjct: 2962 GGS---LP--ARHQTHGSQ-------LRLHLVSPADS-GEYVCRAASGPGPE-QEASFTV 3007

Query: 390  T------SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGEALIQNH 442
            T      S      P+I+  P + T+     A F C       PI + W    + L  N 
Sbjct: 3008 TVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNV 3067

Query: 443  RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
              +  N   + +     S+ GTY CVAS+ +G
Sbjct: 3068 HIS-PNGSIITIVGTRPSNHGTYRCVASNAYG 3098



 Score = 93.9 bits (223), Expect = 2e-17
 Identities = 82/286 (28%), Positives = 120/286 (41%), Gaps = 23/286 (8%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAG 64
            + +G  P +   P   T +       +C         +RW+K GG L    + +      
Sbjct: 3394 IPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSVQD----- 3448

Query: 65   GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
            G+  ++       S  G Y C+A   +G A++    +  A+      +    +    G  
Sbjct: 3449 GVLRIQNLD---QSCQGTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHA 3505

Query: 125  VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIAR 183
            V  ECL   G P+P V W K G      G  R  +V  G +V I      DAG+Y+C A 
Sbjct: 3506 VEFECLA-LGDPKPQVTWSKVG------GHLRPGIVQSGGVVRIAHVELADAGQYRCTAT 3558

Query: 184  NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
            NAAGT +S +  L +   P  I+ P++V    GS+  F C   G P PD+ W +   G  
Sbjct: 3559 NAAGTTQSHVLLL-VQALPQ-ISMPQEVRVPAGSAAVFPCIASGYPTPDISWSK-LDGSL 3615

Query: 244  MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
             P  R   L++  L L +V   D G Y C A N  G V A  +L V
Sbjct: 3616 PPDSR---LENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQV 3658



 Score = 93.1 bits (221), Expect = 4e-17
 Identities = 93/353 (26%), Positives = 137/353 (38%), Gaps = 46/353 (13%)

Query: 5    YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
            +V  G  P +   P    V   +   L CRA G PS  I W K G  +            
Sbjct: 1949 HVHGGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARSERTDIA 2008

Query: 65   GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE------FRLEPESKQ 118
             L     T     +DAG Y C AT+  GTA++R   + V VL          ++E  S  
Sbjct: 2009 TLLIPAIT----TADAGFYLCVATSPAGTAQAR---IQVVVLSASDASPPPVKIESSSPS 2061

Query: 119  SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY 178
              +G T+ L C+   GS    V W + G +L     +++H   G  L +      D+G Y
Sbjct: 2062 VTEGQTLDLNCV-VAGSAHAQVTWYRRGGSL--PPHTQVH---GSRLRLPQVSPADSGEY 2115

Query: 179  QCIARNAAGTRESAIATLKIH--------------IKPYLITGPEDVVAQTGSSVTFQCR 224
             C   N +G +E++I    +H               +P  I      VA+ G ++   C 
Sbjct: 2116 VCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAE-GQTLDLNCV 2174

Query: 225  VGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSA 283
            V G     V W +   GG++P    +    GS LRL  V  AD GEY C    + G + A
Sbjct: 2175 VPGQAHAQVTWHKR--GGSLP---ARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEA 2229

Query: 284  SGYLTVYDP------PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
            S  +T+         P + +  +S  V  G     +C   G+    + W   G
Sbjct: 2230 SVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRG 2282



 Score = 82.6 bits (195), Expect = 6e-14
 Identities = 117/500 (23%), Positives = 180/500 (36%), Gaps = 69/500 (13%)

Query: 23   VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
            VA  +   LNC   G     + W+K G  + S  H++    G    L   H    +D+G 
Sbjct: 2738 VAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSH-HQT---RGSRLRL---HHVSPADSGE 2790

Query: 83   YWCEATNSYGTAR---------SRNATLHVAVL--REEFRLEPESKQSAQGDTVVLECLP 131
            Y C    S G            S ++ +HV         R+EP S + A+G T+ L+C+ 
Sbjct: 2791 YVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVV 2850

Query: 132  PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
            P G     V W K G  L        H V G  L +      D+G Y C    ++GT E+
Sbjct: 2851 P-GQAHAQVTWHKRGGNL-----PARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEA 2904

Query: 192  AIATLKIHIKPYLITGP---EDVVAQTGSS-------VTFQCRVGGDPLPDVLWRRSAGG 241
            ++        P  I  P   + +  +  SS       +   C V G     V W +   G
Sbjct: 2905 SVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKR--G 2962

Query: 242  GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP--------- 292
            G++P           LRL  V  AD GEY C A +  G    + +     P         
Sbjct: 2963 GSLPARHQT--HGSQLRLHLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLR 3020

Query: 293  -PSINLSPNSVNVESGNVARFTCTATGRPEP-TMFWSVEGNRTIIFPGMSRDKYHATAVF 350
             P I++ P S  V+ G  A F C       P ++ W               D  H   + 
Sbjct: 3021 SPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQEL-------EDNVH---IS 3070

Query: 351  DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT-L 409
               +++TI  T +  +  T  C A N  G +     L+V       PP ++  P     +
Sbjct: 3071 PNGSIITIVGT-RPSNHGTYRCVASNAYGVAQSVVNLSV-----HGPPTVSVLPEGPVWV 3124

Query: 410  PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN---VTNDGTLVLKDLDKSDSGTYT 466
             +       C +   P     W        +  +R    + +   L +     SD+GTY 
Sbjct: 3125 KVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYV 3184

Query: 467  CVASSRHGKYVWSGALLVDS 486
            C+A +  G       ++VD+
Sbjct: 3185 CLAQNALGTAQKQVEVIVDT 3204



 Score = 70.1 bits (164), Expect = 3e-10
 Identities = 73/291 (25%), Positives = 115/291 (39%), Gaps = 21/291 (7%)

Query: 208  PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267
            P   +   G S + +C+V G P     W R   G  +P G  +      L   +V  +D 
Sbjct: 1683 PARSIVPQGGSHSLRCQVSGSPPHYFYWSRE-DGRPVPSGTQQRHQGSELHFPSVQPSDA 1741

Query: 268  GEYSCEAENSVGAVSASGYLTVYDPPSINLS-----PNSVNVESGNVARFTCTATGR-PE 321
            G Y C   N   + ++   L V + PS  ++       S +V  G    F CTA  + P 
Sbjct: 1742 GVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAKSKSPA 1801

Query: 322  PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381
             T+ W+   N  +  P  + D       F+G  +LTI +   +D+  T VC+  N     
Sbjct: 1802 YTLVWTRLHNGKL--PTRAMD-------FNG--ILTIRNVQLSDA-GTYVCTGSNMFAMD 1849

Query: 382  FVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN 441
                 L V +      P+++  P   T+    +A F C+A  +P P + W   G    Q 
Sbjct: 1850 QGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW--TGGPGGQL 1907

Query: 442  HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
              +   + G L L  ++ +D   Y C A S  G+ V    L V     P +
Sbjct: 1908 PAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRV 1958



 Score = 51.6 bits (118), Expect = 1e-04
 Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 4/82 (4%)

Query: 397 PPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TL 452
           PP +   P       +   V F C AI  P PII W      +  + R  VT++G   TL
Sbjct: 405 PPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTL 464

Query: 453 VLKDLDKSDSGTYTCVASSRHG 474
           +++D+ +SD G YTC A +  G
Sbjct: 465 IIRDVKESDQGAYTCEAMNARG 486



 Score = 48.4 bits (110), Expect = 0.001
 Identities = 32/85 (37%), Positives = 47/85 (55%), Gaps = 7/85 (8%)

Query: 202 PYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDD---GS 256
           P ++T P E + A  G +VTF C   G P P + WR     G++P   RV V  +   G+
Sbjct: 406 PQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWR--LNWGHIPSHPRVTVTSEGGRGT 463

Query: 257 LRLDNVILADEGEYSCEAENSVGAV 281
           L + +V  +D+G Y+CEA N+ G V
Sbjct: 464 LIIRDVKESDQGAYTCEAMNARGMV 488



 Score = 42.7 bits (96), Expect = 0.059
 Identities = 25/74 (33%), Positives = 38/74 (51%), Gaps = 2/74 (2%)

Query: 115 ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQT 173
           ES Q+++G TV   C+   G P P + W+ N   +       +    G G L+I+D +++
Sbjct: 414 ESIQASRGQTVTFTCVAI-GVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKES 472

Query: 174 DAGRYQCIARNAAG 187
           D G Y C A NA G
Sbjct: 473 DQGAYTCEAMNARG 486



 Score = 39.5 bits (88), Expect = 0.55
 Identities = 25/82 (30%), Positives = 36/82 (43%), Gaps = 2/82 (2%)

Query: 12  PYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
           P ++  P + +  +R Q  T  C A G P+P I W      + S    ++   GG   L 
Sbjct: 406 PQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLI 465

Query: 71  ATHGRVHSDAGVYWCEATNSYG 92
               +  SD G Y CEA N+ G
Sbjct: 466 IRDVK-ESDQGAYTCEAMNARG 486


>UniRef50_UPI0000E46295 Cluster: PREDICTED: similar to Down syndrome
            cell adhesion molecule, partial; n=2; Strongylocentrotus
            purpuratus|Rep: PREDICTED: similar to Down syndrome cell
            adhesion molecule, partial - Strongylocentrotus
            purpuratus
          Length = 2430

 Score =  142 bits (345), Expect = 4e-32
 Identities = 191/825 (23%), Positives = 318/825 (38%), Gaps = 86/825 (10%)

Query: 31   LNCRAGGSPSPAIRWYKGGVLVVSD---THRSILPAGGLFFLRATHGR-VHSDAGVYWCE 86
            L+C   G+P+P + W + G+ + +D   T   ++             R V  D G+Y CE
Sbjct: 866  LSCTVAGNPTPDVTWLRDGLPIPTDPRYTFNDVINEDSDVISYLNISRLVSEDGGLYRCE 925

Query: 87   ATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146
            AT+  G  +  +  ++V + R   R  P+   +  G  V + C    G P  ++ W K  
Sbjct: 926  ATSELGAVQHEDR-INV-IGRPLVRPLPDVI-AIDGTDVSIHCHVV-GFPITSITWYKGL 981

Query: 147  QTLLFDGDSRMHLVDGGNLVIQDARQT-DAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
             TL      R ++   G LVI D     D G Y C+A NA G R ++   L + + P +I
Sbjct: 982  TTL--PSSMRHNVFPNGTLVIADVTSYGDGGEYTCVASNARGDRSASDMDLIVKVPP-VI 1038

Query: 206  TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR----VKVLDDGSLRLDN 261
               E +  + G      C V     P + +R    G  +P G     V      SL + +
Sbjct: 1039 QPIEPLTLRQGQRTQLMCIVTRGDYP-IHFRWLKDGETIPHGVGIEFVNGTFSSSLLIAD 1097

Query: 262  VILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPE 321
                 +G Y+CEA N   AV+ +  LT+  PP   + P++  V   +     C A G+P 
Sbjct: 1098 ASTVHDGRYTCEASNLAAAVNYTTALTIQVPPRFVVEPHNTAVVLNHTVVIACMANGKPN 1157

Query: 322  PTMFWSVEGN--RTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379
            P + W        T  F  +  D             L I +    D+    +C   N  G
Sbjct: 1158 PDVQWKKAPGPITTTNFRDLPDDPRFEMQENGS---LVIREARVEDA-GYYLCHISNSVG 1213

Query: 380  SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL- 438
                   LTV       P        N T+ +       C A       I W        
Sbjct: 1214 MESKTATLTVFV-----PATFEQQQQNVTVELTESITLECIATGHQPLEIMWSKNDVPFN 1268

Query: 439  -IQNHRRNV--TNDGTLVLKDLD-----KSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
             +   R ++    DG  VL  +      + D+ TY C+A + HG          D  +  
Sbjct: 1269 RLTTARYDIETVTDGDSVLSSMTIFSAVRDDTATYICLAQNLHG---------ADEHV-- 1317

Query: 491  NIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSG 550
             I  +    V   P PPT     N T   V LSW Q +  G+S + G+ +E  +      
Sbjct: 1318 -IQLW----VQEKPEPPTDLHVVNKTSRGVLLSW-QPSFDGNSPVTGFTLEYKNASDAWQ 1371

Query: 551  NNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDD 610
               P+      +I  +     Y +K L P  TY   +   N+ G+S PS     +    +
Sbjct: 1372 TGLPQEHVPADLIGYQ-----YSIKHLHPAYTYHVRIFAFNAIGISDPSK---EILFDTE 1423

Query: 611  SNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRP 670
                W+ TG+    E+    L  +   +    P  +  +++     N   +        P
Sbjct: 1424 EEDAWQ-TGLPQ--EHVPADLIGYQYSIKHLHPAYTYHVRIF--AFNAIGISD------P 1472

Query: 671  LDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDV 730
               I  + E +  + +N +    +T+L+K+T+Y   L  + +   G  S  +   TL+DV
Sbjct: 1473 SKEILFDTEEEVPVETNYIESRTLTNLKKFTRYTIQLRAYNRVNVGPWSPQQFVTTLEDV 1532

Query: 731  PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTT-- 788
            P   P ++    + +T++ + W+ P+    NGI+ GY V   +  +  N+     N +  
Sbjct: 1533 PSEAPHDVSARSVGSTSIMVFWNAPDQVSLNGILQGYRVY--YRPIRENEGFFLSNISFS 1590

Query: 789  -------VHQATSLI--MTNLTSGVSYSVQIAAETIIGLGPFSQK 824
                   +++ T L   + NL    +YS+ + A T +G G  S++
Sbjct: 1591 EDELDYQIYETTELFAELHNLQKFTNYSLSVVAHTRVGEGVRSEE 1635



 Score =  134 bits (325), Expect = 1e-29
 Identities = 107/376 (28%), Positives = 162/376 (43%), Gaps = 22/376 (5%)

Query: 17   QPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75
            +PL DV        +++C   G P  +I WYKG   + S    ++ P G L     T   
Sbjct: 948  RPLPDVIAIDGTDVSIHCHVVGFPITSITWYKGLTTLPSSMRHNVFPNGTLVIADVTS-- 1005

Query: 76   VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGS 135
             + D G Y C A+N+ G   + +  L V V      +EP + +  QG    L C+  RG 
Sbjct: 1006 -YGDGGEYTCVASNARGDRSASDMDLIVKVPPVIQPIEPLTLR--QGQRTQLMCIVTRGD 1062

Query: 136  PEPNVYWKKNGQTLLFD-GDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194
               +  W K+G+T+    G   ++     +L+I DA     GRY C A N A       A
Sbjct: 1063 YPIHFRWLKDGETIPHGVGIEFVNGTFSSSLLIADASTVHDGRYTCEASNLAAAVNYTTA 1122

Query: 195  TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG------GNMPLG- 247
             L I + P  +  P +       +V   C   G P PDV W+++ G        ++P   
Sbjct: 1123 -LTIQVPPRFVVEPHNTAVVLNHTVVIACMANGKPNPDVQWKKAPGPITTTNFRDLPDDP 1181

Query: 248  RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESG 307
            R ++ ++GSL +    + D G Y C   NSVG  S +  LTV+ P +      +V VE  
Sbjct: 1182 RFEMQENGSLVIREARVEDAGYYLCHISNSVGMESKTATLTVFVPATFEQQQQNVTVELT 1241

Query: 308  NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL---TINDTDKN 364
                  C ATG     + WS      + F  ++  +Y    V DG +VL   TI    ++
Sbjct: 1242 ESITLECIATGHQPLEIMWS---KNDVPFNRLTTARYDIETVTDGDSVLSSMTIFSAVRD 1298

Query: 365  DSRNTIVCSAVNYAGS 380
            D+  T +C A N  G+
Sbjct: 1299 DTA-TYICLAQNLHGA 1313



 Score =  132 bits (319), Expect = 6e-29
 Identities = 129/492 (26%), Positives = 195/492 (39%), Gaps = 44/492 (8%)

Query: 11   APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
            AP +I+   D T+   +   L C A G P P  +W K GV V     RS+   GG   L 
Sbjct: 666  APELIQSKADFTLRGGETVELPCVASGYPLPTYQWTKDGVPVTPGDSRSL--RGGNLLLS 723

Query: 71   ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE--PESKQSAQGDTVVLE 128
                    +AG Y CEA N  G      +T    ++R+   +   P+ +    G      
Sbjct: 724  NVQ---LENAGRYDCEAVNDLGAV----STTRNVIVRDSIAVYFYPQKRSVDVGAFATFN 776

Query: 129  CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
            C    G P   V W KN Q L  DGD R+ + + G +V+   R+ D G YQC+A N+  T
Sbjct: 777  C-SVSGYPIEQVTWYKNAQPL--DGDDRVTVYENGTMVVGGMRRDDRGMYQCVASNSWQT 833

Query: 189  RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
            +E+ +       KP ++    +   Q G ++   C V G+P PDV W R   G  +P   
Sbjct: 834  QEATMQLSLGAAKPIMLAHFTNQTLQPGPNLQLSCTVAGNPTPDVTWLRD--GLPIPTDP 891

Query: 249  VKVLDD---------GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
                +D           L +  ++  D G Y CEA + +GAV     + V   P +   P
Sbjct: 892  RYTFNDVINEDSDVISYLNISRLVSEDGGLYRCEATSELGAVQHEDRINVIGRPLVRPLP 951

Query: 300  NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
            + + ++  +V+   C   G P  ++ W  +G  T+  P   R       VF   T++  +
Sbjct: 952  DVIAIDGTDVS-IHCHVVGFPITSITW-YKGLTTL--PSSMRHN-----VFPNGTLVIAD 1002

Query: 360  DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419
             T   D      C A N  G         +     + PP+I       TL         C
Sbjct: 1003 VTSYGDG-GEYTCVASNARGDRSASDMDLIV----KVPPVI-QPIEPLTLRQGQRTQLMC 1056

Query: 420  TAICTPEPI-IAWYFEGEAL---IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
                   PI   W  +GE +   +     N T   +L++ D      G YTC AS+    
Sbjct: 1057 IVTRGDYPIHFRWLKDGETIPHGVGIEFVNGTFSSSLLIADASTVHDGRYTCEASNLAAA 1116

Query: 476  YVWSGALLVDSP 487
              ++ AL +  P
Sbjct: 1117 VNYTTALTIQVP 1128



 Score =  116 bits (279), Expect = 4e-24
 Identities = 131/491 (26%), Positives = 193/491 (39%), Gaps = 74/491 (15%)

Query: 6   VTSGEAPYIIEQPLDVTV-ARHQPATLNCRAGGSPSPAIRWYKG--GVLVVSDTHRSILP 62
           V+  + P   + P  V   A  Q   L C A G P+P +RW     G  V +  H  I  
Sbjct: 493 VSGNKGPQFYQVPPSVVAFATTQGGRLTCSAIGDPTPVVRWVMAADGSAVQNIEHSRIAD 552

Query: 63  AGGL-----FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK 117
             G      F  +     VH   GVY C ATN  G+ RS                 P+ +
Sbjct: 553 GNGTLSFPPFSSKEIIPEVHD--GVYRCIATNRIGSIRS-----------------PDIR 593

Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR 177
            +A  DT    C+        ++Y +  G+        R  ++  G L I+D R  DAG+
Sbjct: 594 VNA--DTWTSVCI--------SIYPRLRGE-------GRFSVLPSGELHIRDVRDRDAGQ 636

Query: 178 YQCIARNAAGTRESAIATLKIHIKPYLITGPE------DVVAQTGSSVTFQCRVGGDPLP 231
           Y+C  RN             +H+   + T PE      D   + G +V   C   G PLP
Sbjct: 637 YRCTVRNRLTNNNKVSPPAVLHVAEPVNTAPELIQSKADFTLRGGETVELPCVASGYPLP 696

Query: 232 DVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
              W +   G  +  G  + L  G+L L NV L + G Y CEA N +GAVS +  + V D
Sbjct: 697 TYQWTKD--GVPVTPGDSRSLRGGNLLLSNVQLENAGRYDCEAVNDLGAVSTTRNVIVRD 754

Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
             ++   P   +V+ G  A F C+ +G P   + W          P    D+     V++
Sbjct: 755 SIAVYFYPQKRSVDVGAFATFNCSVSGYPIEQVTWYKNAQ-----PLDGDDR---VTVYE 806

Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
             T++      + D R    C A N    S+   + T+        PI+    +NQTL  
Sbjct: 807 NGTMVV--GGMRRDDRGMYQCVASN----SWQTQEATMQLSLGAAKPIMLAHFTNQTLQP 860

Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHR---RNVTNDGTLVLKDLDKS-----DSG 463
                  CT    P P + W  +G  +  + R    +V N+ + V+  L+ S     D G
Sbjct: 861 GPNLQLSCTVAGNPTPDVTWLRDGLPIPTDPRYTFNDVINEDSDVISYLNISRLVSEDGG 920

Query: 464 TYTCVASSRHG 474
            Y C A+S  G
Sbjct: 921 LYRCEATSELG 931



 Score =  106 bits (255), Expect = 3e-21
 Identities = 124/495 (25%), Positives = 201/495 (40%), Gaps = 43/495 (8%)

Query: 11   APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
            A Y   Q   V V     AT NC   G P   + WYK    +  D   ++   G +    
Sbjct: 757  AVYFYPQKRSVDVGAF--ATFNCSVSGYPIEQVTWYKNAQPLDGDDRVTVYENGTM---- 810

Query: 71   ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV-LREEFRLEPESKQSAQ-GDTVVLE 128
               G    D G+Y C A+NS+ T   + AT+ +++   +   L   + Q+ Q G  + L 
Sbjct: 811  VVGGMRRDDRGMYQCVASNSWQT---QEATMQLSLGAAKPIMLAHFTNQTLQPGPNLQLS 867

Query: 129  CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN------LVIQDARQTDAGRYQCIA 182
            C    G+P P+V W ++G  +  D     + V   +      L I      D G Y+C A
Sbjct: 868  CTVA-GNPTPDVTWLRDGLPIPTDPRYTFNDVINEDSDVISYLNISRLVSEDGGLYRCEA 926

Query: 183  RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
             +  G  +     + +  +P L+    DV+A  G+ V+  C V G P+  + W +  G  
Sbjct: 927  TSELGAVQHE-DRINVIGRP-LVRPLPDVIAIDGTDVSIHCHVVGFPITSITWYK--GLT 982

Query: 243  NMPLG-RVKVLDDGSLRLDNVI-LADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
             +P   R  V  +G+L + +V    D GEY+C A N+ G  SAS    +   P +     
Sbjct: 983  TLPSSMRHNVFPNGTLVIADVTSYGDGGEYTCVASNARGDRSASDMDLIVKVPPVIQPIE 1042

Query: 301  SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
             + +  G   +  C  T    P  F  ++   TI   G+  +  + T  F   ++L  + 
Sbjct: 1043 PLTLRQGQRTQLMCIVTRGDYPIHFRWLKDGETIPH-GVGIEFVNGT--FSS-SLLIADA 1098

Query: 361  TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
            +  +D R T  C A N A +      LT+     + PP     P N  + +    V  C 
Sbjct: 1099 STVHDGRYT--CEASNLAAAVNYTTALTI-----QVPPRFVVEPHNTAVVLNHTVVIACM 1151

Query: 421  AICTPEPIIAWYFEGEALIQNHRRNVTND--------GTLVLKDLDKSDSGTYTCVASSR 472
            A   P P + W      +   + R++ +D        G+LV+++    D+G Y C  S+ 
Sbjct: 1152 ANGKPNPDVQWKKAPGPITTTNFRDLPDDPRFEMQENGSLVIREARVEDAGYYLCHISNS 1211

Query: 473  HGKYVWSGALLVDSP 487
             G    +  L V  P
Sbjct: 1212 VGMESKTATLTVFVP 1226



 Score = 61.7 bits (143), Expect = 1e-07
 Identities = 37/122 (30%), Positives = 57/122 (46%), Gaps = 3/122 (2%)

Query: 83   YWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTVVLECLPPRGSPEPNV 140
            +W +A+   G   S      + + R   R+   S    +     V L+CLP  G P   V
Sbjct: 1717 FWVKASTIAGQGESSRIATEIPMSRVPARIMSFSTTLMTPWKRGVTLDCLPV-GDPVLTV 1775

Query: 141  YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
             WKKN    +   D R+ +++ G+LVIQ  + TDAG Y C A N  G+ +S    +++  
Sbjct: 1776 EWKKNRLPNVLKPDGRIDILENGSLVIQSVQSTDAGNYTCRAINEYGSSDSITVRVQVLA 1835

Query: 201  KP 202
             P
Sbjct: 1836 PP 1837



 Score = 57.2 bits (132), Expect = 3e-06
 Identities = 50/199 (25%), Positives = 93/199 (46%), Gaps = 20/199 (10%)

Query: 639  IEATPIDSKTIKLMWEILNFYYLEGLF----IYFRP--------LDNITI-EYEMKTILH 685
            + A  + S +I + W   +   L G+     +Y+RP        L NI+  E E+   ++
Sbjct: 1540 VSARSVGSTSIMVFWNAPDQVSLNGILQGYRVYYRPIRENEGFFLSNISFSEDELDYQIY 1599

Query: 686  SNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNT 745
                   E+ +L+K+T Y   ++   +  EG  S  ++ +T  DVP+  P +I+    + 
Sbjct: 1600 ETTELFAELHNLQKFTNYSLSVVAHTRVGEGVRSEEKIVRTEQDVPEA-PADIKAHAASP 1658

Query: 746  TTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT-SLIMTNLTSGV 804
            T++ + W PP L L NGIIT Y++ + + +    ++ V     +   T   ++ +L +  
Sbjct: 1659 TSIMVSWLPP-LYL-NGIITHYHLNIQYRE---GENEVRQEKELDPTTYYYLVEDLQTDY 1713

Query: 805  SYSVQIAAETIIGLGPFSQ 823
             Y   + A TI G G  S+
Sbjct: 1714 EYDFWVKASTIAGQGESSR 1732



 Score = 56.0 bits (129), Expect = 6e-06
 Identities = 53/203 (26%), Positives = 83/203 (40%), Gaps = 17/203 (8%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P  + +P +  V  +    + C A G P+P ++W K    + +   R  LP    F ++ 
Sbjct: 1129 PRFVVEPHNTAVVLNHTVVIACMANGKPNPDVQWKKAPGPITTTNFRD-LPDDPRFEMQE 1187

Query: 72   THGRV-----HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
                V       DAG Y C  +NS G   S+ ATL V V    F  + ++      +++ 
Sbjct: 1188 NGSLVIREARVEDAGYYLCHISNSVG-MESKTATLTVFV-PATFEQQQQNVTVELTESIT 1245

Query: 127  LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL---VDG----GNLVIQDARQTDAGRYQ 179
            LEC+   G     + W KN         +R  +    DG     ++ I  A + D   Y 
Sbjct: 1246 LECI-ATGHQPLEIMWSKNDVPFNRLTTARYDIETVTDGDSVLSSMTIFSAVRDDTATYI 1304

Query: 180  CIARNAAGTRESAIATLKIHIKP 202
            C+A+N  G  E  I  L +  KP
Sbjct: 1305 CLAQNLHGADEHVI-QLWVQEKP 1326



 Score = 48.8 bits (111), Expect = 9e-04
 Identities = 32/102 (31%), Positives = 51/102 (50%), Gaps = 4/102 (3%)

Query: 219  VTFQCRVGGDPLPDVLWRRSAGGGNM-PLGRVKVLDDGSLRLDNVILADEGEYSCEAENS 277
            VT  C   GDP+  V W+++     + P GR+ +L++GSL + +V   D G Y+C A N 
Sbjct: 1761 VTLDCLPVGDPVLTVEWKKNRLPNVLKPDGRIDILENGSLVIQSVQSTDAGNYTCRAINE 1820

Query: 278  VGAV-SASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATG 318
             G+  S +  + V  PP  N    ++   S N  +    +TG
Sbjct: 1821 YGSSDSITVRVQVLAPP--NPPQLTIGSTSNNAIKVNWRSTG 1860


>UniRef50_Q4RE92 Cluster: Chromosome undetermined SCAF15134, whole
            genome shotgun sequence; n=488; root|Rep: Chromosome
            undetermined SCAF15134, whole genome shotgun sequence -
            Tetraodon nigroviridis (Green puffer)
          Length = 10495

 Score =  142 bits (344), Expect = 5e-32
 Identities = 133/473 (28%), Positives = 202/473 (42%), Gaps = 34/473 (7%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
            DV+V + +P TL C   G+P   + WYK G  V +    +I        L          
Sbjct: 9214 DVSVEKGKPLTLECTYTGTPKITVNWYKDGQQVFASYKYNITTTESSCILECLSTDDKEA 9273

Query: 80   AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVLECLPPRGSPEP 138
            AG Y CE +N  G      A   V++L   + +E  E  +   GD V L+C    G+PE 
Sbjct: 9274 AGKYLCEVSNDAGRDTCEAA---VSILEPPYFVESLEPMEVTAGDAVCLKC-KVAGTPEI 9329

Query: 139  NVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
             V W K    +      R+    G   L +  A + D G Y C A N  G   S+     
Sbjct: 9330 KVSWFKADGKVRSSPTCRLEYTKGVACLKLSKATKADIGEYSCKAENRIGATSSSCRLNV 9389

Query: 198  IHIKPYLITGPEDVVA--QT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL-D 253
            +  K    T P+ + +  QT G  + F+CR+ G    +V W R  G      G   +L D
Sbjct: 9390 LEAKTPP-TFPKKITSLQQTEGQPIRFECRIAGSSPIEVSWLRD-GEPLKAGGEFSMLYD 9447

Query: 254  DGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP--PSI---NLSPNSVNVES 306
            D +  L+++   +   GEY+C A NSVG+ S    LT+ +P  P +    L+P  V +  
Sbjct: 9448 DNTAVLQIERGEMRHSGEYTCVATNSVGSTSCRAKLTLQEPRYPPVFDRKLAPQEVTM-- 9505

Query: 307  GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
            G+     C  TG     + WS + ++ I     S   Y+ + V D    LTI   DK D+
Sbjct: 9506 GDSIELECHMTGSAPIKVTWS-KDHKDI----RSGGNYNISCV-DNTPHLTILKADKGDT 9559

Query: 367  RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
                 C A+N  G   V     VT  + + PP+ T  PS      +   V     +   +
Sbjct: 9560 -GKYFCHAMNDVGK--VSCSSDVTVKERKNPPVFTKKPSEHMEDTEGRLVKIEGRVSGSQ 9616

Query: 427  PI-IAWYFEGEALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
            P+ ++WY E   +  + + ++   +N   L +K    +DSG YTC AS+  G+
Sbjct: 9617 PMSVSWYKEDAEIHSSDKYDISFKSNVAVLCIKSSHVTDSGRYTCQASNEAGR 9669



 Score =  133 bits (321), Expect = 3e-29
 Identities = 121/462 (26%), Positives = 187/462 (40%), Gaps = 22/462 (4%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            E P I+E+P  + V        N    G+P   I+W+K    ++S    S++       L
Sbjct: 8055 EPPCILEKPESMNVLPGSKVHFNVLLSGTPPLTIKWFKNQKEILSSADCSVIKDNTSTSL 8114

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
                 +  SD+G Y CE  N  G+  S  ATL V    +  R       +  G   V EC
Sbjct: 8115 ALFFAK-SSDSGEYRCEIQNDVGST-SCQATLFVKEPPKFTRTPARVSVTRLGQNKVFEC 8172

Query: 130  LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGT 188
                G+PE +VYW K G  +      +M  ++   +L +      D+G Y C ARN AG+
Sbjct: 8173 -QVTGTPEIDVYWFKEGSEIHPSERYQMSFLNSLASLEVCGTETKDSGLYYCEARNEAGS 8231

Query: 189  RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
             ES    LK+   P +I           S+   +C+V G    +V W R A         
Sbjct: 8232 -ESCSMELKVKEIPTIIKDLAPAELVKDSTAHLECQVTGTSPFEVTWYRDAKEIKSSAKH 8290

Query: 249  VKVLDDGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
                 +G+L L+      AD GEY C   N VG+ ++   L + +PP+      + +   
Sbjct: 8291 SFSQINGTLGLEVHKCGAADVGEYQCTVANEVGSCTSKATLKLKEPPTFTKKLENTDTVL 8350

Query: 307  GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
            G +A F C   G P  ++ W  + N  +  P + R         + V +L I   +   S
Sbjct: 8351 GKMAVFQCVVEGSPTLSVQWQKDDNWILEDPKIER------TFENNVAILKIPACEAVHS 8404

Query: 367  RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
                 C  VN AG +     LTV     + PP IT  P    + +       C    +P 
Sbjct: 8405 -GKYSCQVVNEAGQTKCSATLTV-----QEPPQITEKPEVIKVTVGDPVSLDCKVTGSPA 8458

Query: 427  PIIAWYFEGEAL--IQNHRRNVTND-GTLVLKDLDKSDSGTY 465
              + W  EG+ L  I+ H+    N+  +L ++  ++ D G Y
Sbjct: 8459 LKVKWMKEGKELQSIRQHKLVFENNISSLKIQAAEREDEGEY 8500



 Score =  132 bits (319), Expect = 6e-29
 Identities = 124/490 (25%), Positives = 197/490 (40%), Gaps = 23/490 (4%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
            +T  E   I ++   ++V +  PATL  R  G+      W K G  ++S     +L    
Sbjct: 7862 LTVKEPAEITDEAKSISVTQGDPATLEARFSGTKPLRAMWIKAGKELISGQRYKVLSTDS 7921

Query: 66   LFFLRATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDT 124
               L+  +    SD G Y    +N  G +      T+   ++   F  + +  +  +   
Sbjct: 7922 SSVLK-INKTDKSDGGEYTFRVSNDVGQSSCEVTLTILDQIIPPSFTRKLKQTEGIKASF 7980

Query: 125  VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIAR 183
              LECL   GS    V+W K+ + +  D   +    +    L I D    D G Y CIA+
Sbjct: 7981 AHLECL-VSGSLPITVHWYKDDKEIQADHKHKCTFFENVAFLEISDLDSKDGGSYTCIAK 8039

Query: 184  NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-- 241
            N AG  + + A L +   P ++  PE +    GS V F   + G P   + W ++     
Sbjct: 8040 NKAGAVQCS-AILLVKEPPCILEKPESMNVLPGSKVHFNVLLSGTPPLTIKWFKNQKEIL 8098

Query: 242  GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
             +     +K     SL L     +D GEY CE +N VG+ S    L V +PP    +P  
Sbjct: 8099 SSADCSVIKDNTSTSLALFFAKSSDSGEYRCEIQNDVGSTSCQATLFVKEPPKFTRTPAR 8158

Query: 302  VNV-ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
            V+V   G    F C  TG PE  ++W  EG+   I P    ++Y   +  + +  L +  
Sbjct: 8159 VSVTRLGQNKVFECQVTGTPEIDVYWFKEGSE--IHPS---ERYQ-MSFLNSLASLEVCG 8212

Query: 361  TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
            T+  DS     C A N AGS     +L V     +  P I    +   L   S A   C 
Sbjct: 8213 TETKDS-GLYYCEARNEAGSESCSMELKV-----KEIPTIIKDLAPAELVKDSTAHLECQ 8266

Query: 421  AICTPEPIIAWYFEGEALIQNHRRNVTN-DGTLVLK--DLDKSDSGTYTCVASSRHGKYV 477
               T    + WY + + +  + + + +  +GTL L+      +D G Y C  ++  G   
Sbjct: 8267 VTGTSPFEVTWYRDAKEIKSSAKHSFSQINGTLGLEVHKCGAADVGEYQCTVANEVGSCT 8326

Query: 478  WSGALLVDSP 487
                L +  P
Sbjct: 8327 SKATLKLKEP 8336



 Score =  131 bits (317), Expect = 1e-28
 Identities = 125/531 (23%), Positives = 214/531 (40%), Gaps = 28/531 (5%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            E   I+++P  ++V     A L  +  G+P    +W+K G+ + S     I  +  +  L
Sbjct: 8921 EPAKIVDKPDALSVTAGDIAALEVKVCGTPELVTKWFKDGIELASGNKYKISFSRMISCL 8980

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
                     D+G Y  E  N  G   S+ N T+   ++   F  + +   +  G    +E
Sbjct: 8981 NVLSTE-KLDSGEYTFEIMNEVGKDLSKINLTVLDKIIPPSFSRKLKDCHTVVGKAGEME 9039

Query: 129  CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAG 187
            C    GSP   + W  +G+ +    +  +   +   ++ +   + +D+G Y+C A N AG
Sbjct: 9040 C-KVSGSPPFAISWHHDGEEIQSGPNYEISFSNNSCILRVPTLKLSDSGLYKCKAVNEAG 9098

Query: 188  TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
            T E+A AT+ +   P  +  P+ + A  GS+VTF   V G     + W R  G   M  G
Sbjct: 9099 TSETA-ATMDVKEPPSFVVPPQSLEALPGSNVTFSAMVKGSAPLKLKWFR--GAKEMEPG 9155

Query: 248  R-----VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
            R     +   +   L L NV  +  GEY+C+  N  G  S    L++ +P + +     V
Sbjct: 9156 RTCSFSLTSTNQVMLELFNVDRSHAGEYTCQIINDAGKESWPVNLSIKEPAAFSKKLKDV 9215

Query: 303  NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
            +VE G      CT TG P+ T+ W  +G +  +F      KY+ T   +   +L    TD
Sbjct: 9216 SVEKGKPLTLECTYTGTPKITVNWYKDGQQ--VFASY---KYNITTT-ESSCILECLSTD 9269

Query: 363  KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
              ++    +C   N AG       +++       PP          +         C   
Sbjct: 9270 DKEAAGKYLCEVSNDAGRDTCEAAVSILE-----PPYFVESLEPMEVTAGDAVCLKCKVA 9324

Query: 423  CTPEPIIAWYFEGEALIQNH---RRNVTND-GTLVLKDLDKSDSGTYTCVASSRHGKYVW 478
             TPE  ++W F+ +  +++    R   T     L L    K+D G Y+C A +R G    
Sbjct: 9325 GTPEIKVSW-FKADGKVRSSPTCRLEYTKGVACLKLSKATKADIGEYSCKAENRIGATSS 9383

Query: 479  SGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
            S  L V     P     +   +    G P +        + + +SW ++ +
Sbjct: 9384 SCRLNVLEAKTPPTFPKKITSLQQTEGQPIRFECRIAGSSPIEVSWLRDGE 9434



 Score =  124 bits (300), Expect = 1e-26
 Identities = 133/511 (26%), Positives = 207/511 (40%), Gaps = 27/511 (5%)

Query: 27   QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
            Q + L CRA GSP    +W+K  + +      ++     +  L      + +++G Y C 
Sbjct: 7604 QSSRLECRATGSPVIIFKWFKDEMEITPGPKYTMAADDLVASLEIVQCTL-AESGDYVCV 7662

Query: 87   ATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146
            A++  G+   R      A     F    ESK   +G  ++LE     GS    V   KNG
Sbjct: 7663 ASSEAGSDCCRGTVTVKAP--PSFVRSLESKDVVKGSELMLEG-QVSGSAPFTVTLCKNG 7719

Query: 147  QTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
            + +  D   R+ + D    L +      D G YQC   N  G R S    + +   P  +
Sbjct: 7720 KAIRNDKRHRITVKDELIALQVLAVEAGDVGLYQCTVENQVG-RVSCDCHVTLKDPPSFV 7778

Query: 206  TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNV 262
               E++ +  GS V+  C + G     V W +           +++  + +   L + +V
Sbjct: 7779 QKLENLSSLVGSEVSLLCVLKGSEPMVVSWMKD-NHELKEAEHIQITYESNTALLHITDV 7837

Query: 263  ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEP 322
                 G+YSC+A+N  G+ + S  LTV +P  I     S++V  G+ A      +G    
Sbjct: 7838 QRNHAGKYSCQAQNQAGSQTCSALLTVKEPAEITDEAKSISVTQGDPATLEARFSGTKPL 7897

Query: 323  TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
               W   G   I     S  +Y   +  D  +VL IN TDK+D          N  G S 
Sbjct: 7898 RAMWIKAGKELI-----SGQRYKVLST-DSSSVLKINKTDKSDG-GEYTFRVSNDVGQSS 7950

Query: 383  VRGKLTVTSDDDRPPPIITNGPSNQTLPIK-SMAVFPCTAICTPEPIIAWYFEGEALIQN 441
               ++T+T  D   PP  T     QT  IK S A   C    +    + WY + + +  +
Sbjct: 7951 C--EVTLTILDQIIPPSFTR-KLKQTEGIKASFAHLECLVSGSLPITVHWYKDDKEIQAD 8007

Query: 442  HRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAA 498
            H+   T   N   L + DLD  D G+YTC+A ++ G    S  LLV  P  P I   +  
Sbjct: 8008 HKHKCTFFENVAFLEISDLDSKDGGSYTCIAKNKAGAVQCSAILLVKEP--PCI-LEKPE 8064

Query: 499  DVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
             ++ LPG              +T+ W +N K
Sbjct: 8065 SMNVLPGSKVHFNVLLSGTPPLTIKWFKNQK 8095



 Score =  120 bits (290), Expect = 2e-25
 Identities = 122/495 (24%), Positives = 193/495 (38%), Gaps = 27/495 (5%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            E P  +  P  +        T +    GS    ++W++G   +      S         +
Sbjct: 9110 EPPSFVVPPQSLEALPGSNVTFSAMVKGSAPLKLKWFRGAKEMEPGRTCSFSLTSTNQVM 9169

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
                    S AG Y C+  N  G   S    L +      F  + +     +G  + LEC
Sbjct: 9170 LELFNVDRSHAGEYTCQIINDAGK-ESWPVNLSIKE-PAAFSKKLKDVSVEKGKPLTLEC 9227

Query: 130  LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTD----AGRYQCIARNA 185
                G+P+  V W K+GQ +      + ++    +  I +   TD    AG+Y C   N 
Sbjct: 9228 TYT-GTPKITVNWYKDGQQVF--ASYKYNITTTESSCILECLSTDDKEAAGKYLCEVSND 9284

Query: 186  AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNM 244
            AG R++  A + I   PY +   E +    G +V  +C+V G P   V W ++ G   + 
Sbjct: 9285 AG-RDTCEAAVSILEPPYFVESLEPMEVTAGDAVCLKCKVAGTPEIKVSWFKADGKVRSS 9343

Query: 245  PLGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLSPN 300
            P  R++       L+L     AD GEYSC+AEN +GA S+S  L V +   PP+      
Sbjct: 9344 PTCRLEYTKGVACLKLSKATKADIGEYSCKAENRIGATSSSCRLNVLEAKTPPTFPKKIT 9403

Query: 301  SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
            S+    G   RF C   G     + W  +G      P  +  ++ +    D   VL I  
Sbjct: 9404 SLQQTEGQPIRFECRIAGSSPIEVSWLRDGE-----PLKAGGEF-SMLYDDNTAVLQIER 9457

Query: 361  TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
             +   S     C A N  GS+  R KLT+   + R PP+     + Q + +       C 
Sbjct: 9458 GEMRHS-GEYTCVATNSVGSTSCRAKLTL--QEPRYPPVFDRKLAPQEVTMGDSIELECH 9514

Query: 421  AICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
               +    + W  + + +      N++   N   L +   DK D+G Y C A +  GK  
Sbjct: 9515 MTGSAPIKVTWSKDHKDIRSGGNYNISCVDNTPHLTILKADKGDTGKYFCHAMNDVGKVS 9574

Query: 478  WSGALLVDSPINPNI 492
             S  + V    NP +
Sbjct: 9575 CSSDVTVKERKNPPV 9589



 Score =  113 bits (271), Expect = 4e-23
 Identities = 119/510 (23%), Positives = 202/510 (39%), Gaps = 28/510 (5%)

Query: 31   LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
            + C+  GSP  AI W+  G  + S  +  I  +     LR    ++ SD+G+Y C+A N 
Sbjct: 9038 MECKVSGSPPFAISWHHDGEEIQSGPNYEISFSNNSCILRVPTLKL-SDSGLYKCKAVNE 9096

Query: 91   YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
             GT+ +  AT+ V      F + P+S ++  G  V    +  +GS    + W +  + + 
Sbjct: 9097 AGTSETA-ATMDVKE-PPSFVVPPQSLEALPGSNVTFSAMV-KGSAPLKLKWFRGAKEME 9153

Query: 151  FDGDSRMHLVDGGNLVIQ--DARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208
                    L     ++++  +  ++ AG Y C   N AG +ES    L I          
Sbjct: 9154 PGRTCSFSLTSTNQVMLELFNVDRSHAGEYTCQIINDAG-KESWPVNLSIKEPAAFSKKL 9212

Query: 209  EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE- 267
            +DV  + G  +T +C   G P   V W +                + S  L+ +   D+ 
Sbjct: 9213 KDVSVEKGKPLTLECTYTGTPKITVNWYKDGQQVFASYKYNITTTESSCILECLSTDDKE 9272

Query: 268  --GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325
              G+Y CE  N  G  +    +++ +PP    S   + V +G+     C   G PE  + 
Sbjct: 9273 AAGKYLCEVSNDAGRDTCEAAVSILEPPYFVESLEPMEVTAGDAVCLKCKVAGTPEIKVS 9332

Query: 326  WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385
            W     +    P   R +Y       GV  L ++   K D      C A N  G++    
Sbjct: 9333 WFKADGKVRSSP-TCRLEYTK-----GVACLKLSKATKADI-GEYSCKAENRIGATSSSC 9385

Query: 386  KLTVTSDDDRP--PPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGEALIQNH 442
            +L V      P  P  IT+    +  PI+    F C  I    PI ++W  +GE L    
Sbjct: 9386 RLNVLEAKTPPTFPKKITSLQQTEGQPIR----FECR-IAGSSPIEVSWLRDGEPLKAGG 9440

Query: 443  RRNVTNDGTLVLKDLDKSD---SGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAAD 499
              ++  D    +  +++ +   SG YTCVA++  G       L +  P  P +   + A 
Sbjct: 9441 EFSMLYDDNTAVLQIERGEMRHSGEYTCVATNSVGSTSCRAKLTLQEPRYPPVFDRKLAP 9500

Query: 500  VSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
                 G   +   H      + ++WS+++K
Sbjct: 9501 QEVTMGDSIELECHMTGSAPIKVTWSKDHK 9530



 Score =  109 bits (263), Expect = 3e-22
 Identities = 122/491 (24%), Positives = 198/491 (40%), Gaps = 42/491 (8%)

Query: 27   QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
            QP    CR  GS    + W + G  + +    S+L       L+   G +   +G Y C 
Sbjct: 9411 QPIRFECRIAGSSPIEVSWLRDGEPLKAGGEFSMLYDDNTAVLQIERGEMRH-SGEYTCV 9469

Query: 87   ATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
            ATNS G+   R   TL        F  +   ++   GD++ LEC    GS    V W K+
Sbjct: 9470 ATNSVGSTSCRAKLTLQEPRYPPVFDRKLAPQEVTMGDSIELEC-HMTGSAPIKVTWSKD 9528

Query: 146  GQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRE-SAIATLKIHIKPY 203
             + +   G+  +  VD   +L I  A + D G+Y C A N  G    S+  T+K    P 
Sbjct: 9529 HKDIRSGGNYNISCVDNTPHLTILKADKGDTGKYFCHAMNDVGKVSCSSDVTVKERKNPP 9588

Query: 204  LITG-PEDVVAQT-GSSVTFQCRVGGDPLPDVLW-RRSAGGGNMPLGRVKVLDDGS-LRL 259
            + T  P + +  T G  V  + RV G     V W +  A   +     +    + + L +
Sbjct: 9589 VFTKKPSEHMEDTEGRLVKIEGRVSGSQPMSVSWYKEDAEIHSSDKYDISFKSNVAVLCI 9648

Query: 260  DNVILADEGEYSCEAENSVGAVSAS---GYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316
             +  + D G Y+C+A N  G  S     G      PP  ++    + V+ G      C  
Sbjct: 9649 KSSHVTDSGRYTCQASNEAGRASCCTTVGISEAKKPPVFDVPLKPLTVDEGEKMSLKCHV 9708

Query: 317  TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
             G     + W ++  + +   G ++  +      DG   L I+   + D+ + + C A N
Sbjct: 9709 CGSAPLIIQW-MKDRKELTSGGNTKISFT-----DGTACLEISPASRKDAGDYL-CKATN 9761

Query: 377  YAGSSFVRGKLTV-------TSDDDRP---PPI-------ITNGPSNQTLPIKSMAVFPC 419
             AGS F + K+ V        +  + P    P+           P    +  KS A F  
Sbjct: 9762 DAGSEFSKAKVAVRQKPGAALAPAEAPAVAAPVKRQDNLFFIEEPKAVRVTEKSTATFMT 9821

Query: 420  TAICTPEPIIAWYFEGEALIQNHRRNVTND-----GTLVLKDLDKSDSGTYTCVASSRHG 474
                 P P + W  +G+     H   ++ D       L ++++ +SDSG Y C+AS++HG
Sbjct: 9822 KVGGDPIPSVKW-MKGKWRQMTHGGRISVDQKGQEAKLEIREVTRSDSGQYRCIASNKHG 9880

Query: 475  KYVWSGALLVD 485
            +   S  LLV+
Sbjct: 9881 EIECSSDLLVE 9891



 Score =  106 bits (255), Expect = 3e-21
 Identities = 93/384 (24%), Positives = 145/384 (37%), Gaps = 16/384 (4%)

Query: 10   EAPYIIEQPLDVTVAR-HQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
            E P     P  V+V R  Q     C+  G+P   + W+K G  +       +     L  
Sbjct: 8148 EPPKFTRTPARVSVTRLGQNKVFECQVTGTPEIDVYWFKEGSEIHPSERYQMSFLNSLAS 8207

Query: 69   LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
            L    G    D+G+Y+CEA N  G+  S +  L V  +    + +    +  +  T  LE
Sbjct: 8208 LEVC-GTETKDSGLYYCEARNEAGS-ESCSMELKVKEIPTIIK-DLAPAELVKDSTAHLE 8264

Query: 129  CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAG 187
            C     SP   V W ++ + +          ++G   L +      D G YQC   N  G
Sbjct: 8265 CQVTGTSPF-EVTWYRDAKEIKSSAKHSFSQINGTLGLEVHKCGAADVGEYQCTVANEVG 8323

Query: 188  TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMP 245
            +  S  ATLK+   P      E+     G    FQC V G P   V W++       +  
Sbjct: 8324 SCTSK-ATLKLKEPPTFTKKLENTDTVLGKMAVFQCVVEGSPTLSVQWQKDDNWILEDPK 8382

Query: 246  LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
            + R    +   L++        G+YSC+  N  G    S  LTV +PP I   P  + V 
Sbjct: 8383 IERTFENNVAILKIPACEAVHSGKYSCQVVNEAGQTKCSATLTVQEPPQITEKPEVIKVT 8442

Query: 306  SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
             G+     C  TG P   + W  EG        +   + H     + ++ L I   ++ D
Sbjct: 8443 VGDPVSLDCKVTGSPALKVKWMKEGKE------LQSIRQHKLVFENNISSLKIQAAERED 8496

Query: 366  SRNTIVCSAVNYAGSSFVRGKLTV 389
                I+    N+   +  + +L V
Sbjct: 8497 EGEYIL-EVANHISRTSCKVRLVV 8519



 Score =  105 bits (253), Expect = 6e-21
 Identities = 123/489 (25%), Positives = 188/489 (38%), Gaps = 28/489 (5%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA-GGLFF 68
            E P   ++   VT        L     GS    ++W K    +  D     L     + F
Sbjct: 7210 EPPSFTKRVDSVTAVLGTTVKLQGTVKGSSPITVKWMKDSEYLRDDDPSITLTFDNNVAF 7269

Query: 69   LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQ-GDTVV 126
            L      + S  G Y C+A N  G  +S  ATL V   +E  R+ EP +  S   G++  
Sbjct: 7270 LSIATVAI-SHGGKYVCQAENEAGQQKSE-ATLTV---QEPARVVEPAASISVTAGESAT 7324

Query: 127  LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNA 185
            LE     GSPE  V W K+G+ +      +M + D    + I  A ++D+  Y     N 
Sbjct: 7325 LESTIS-GSPELKVKWFKDGKEMTSGRKCKMTVKDNTATMKILSAEKSDSAEYIMQVSNK 7383

Query: 186  AGTRESAIA-TLKIHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
             G  E   + T+     P   T P   V A  G+  +  C+V G     + W +      
Sbjct: 7384 VGKDECTCSLTVLDRTMPPTFTKPLRRVDANIGNDASLDCKVSGSQPMTIAWFKDDHEIT 7443

Query: 244  M-PLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
              P  +    D   +L++  +  AD G Y C A NS G    SG L V +PP+  + P+ 
Sbjct: 7444 AGPKFQAGFKDHSATLQIAGLEKADSGVYKCRATNSAGFKETSGTLYVKEPPTFTVKPDG 7503

Query: 302  VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
             +V  G+   F    TG    T+ W  E ++ I+  G    K  AT+     + L +   
Sbjct: 7504 QDVIPGSTVSFRAAFTGTAPLTVKWFKE-DKEIVSGGTYFIKKDATS-----SSLELQAV 7557

Query: 362  DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
              +DS     C   N AG       L V      PP  +    +   +     +   C A
Sbjct: 7558 KPSDSAR-YACQVSNDAGKVDCTALLFV----KEPPTFVRKLEATTLVTCGQSSRLECRA 7612

Query: 422  ICTPEPIIAWYFEGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTCVASSRHGKYVW 478
              +P  I  W+ +   +    +  +  D    +L +     ++SG Y CVASS  G    
Sbjct: 7613 TGSPVIIFKWFKDEMEITPGPKYTMAADDLVASLEIVQCTLAESGDYVCVASSEAGSDCC 7672

Query: 479  SGALLVDSP 487
             G + V +P
Sbjct: 7673 RGTVTVKAP 7681



 Score =  105 bits (251), Expect = 1e-20
 Identities = 129/555 (23%), Positives = 212/555 (38%), Gaps = 46/555 (8%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            E P   + P  +   + +  +L C   G+    + W+K    ++      +L  G    L
Sbjct: 8734 EPPSFTKVPEPMEGLKGKDVSLYCELAGTAPFQVTWFKDKKPLMESRKYKMLSEGSSVTL 8793

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVVL 127
                G   +D G Y C+ +NS G+   +     +  LRE   F  +  +     G  V L
Sbjct: 8794 HII-GLESTDIGQYECKVSNSVGSDTCQT----LVKLREPPSFVKKLSNMTVVLGQEVTL 8848

Query: 128  ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ--DARQTDAGRYQCIARNA 185
            +    +GS    V W ++   +L DGD+R    +   + ++   A  + AGRY C   N 
Sbjct: 8849 QATV-KGSEPITVSWVQDKDHILRDGDNRRITFENNTVTLKVFKADASTAGRYTCHLTND 8907

Query: 186  AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGG 241
            AGT E   A L +     ++  P+ +    G     + +V G P     W +     A G
Sbjct: 8908 AGTSE-CFANLNVLEPAKIVDKPDALSVTAGDIAALEVKVCGTPELVTKWFKDGIELASG 8966

Query: 242  GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLS 298
                +   +++    L + +    D GEY+ E  N VG   +   LTV D   PPS +  
Sbjct: 8967 NKYKISFSRMI--SCLNVLSTEKLDSGEYTFEIMNEVGKDLSKINLTVLDKIIPPSFSRK 9024

Query: 299  PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
                +   G      C  +G P   + W  +G      P       +  +  +   +L +
Sbjct: 9025 LKDCHTVVGKAGEMECKVSGSPPFAISWHHDGEEIQSGPN------YEISFSNNSCILRV 9078

Query: 359  NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
                 +DS     C AVN AG+S    +   T D   PP  +    S + LP  ++    
Sbjct: 9079 PTLKLSDS-GLYKCKAVNEAGTS----ETAATMDVKEPPSFVVPPQSLEALPGSNVTF-- 9131

Query: 419  CTAICTPEPIIAWYFEGEALIQNHRR-----NVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
               +    P+   +F G   ++  R        TN   L L ++D+S +G YTC   +  
Sbjct: 9132 SAMVKGSAPLKLKWFRGAKEMEPGRTCSFSLTSTNQVMLELFNVDRSHAGEYTCQIINDA 9191

Query: 474  GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPP-TKPITHNVTDTSVTLSWSQNNKIGS 532
            GK  W   L +  P        +  DVS   G P T   T+  T   +T++W    K G 
Sbjct: 9192 GKESWPVNLSIKEPA---AFSKKLKDVSVEKGKPLTLECTYTGT-PKITVNW---YKDGQ 9244

Query: 533  SSILGYQVEVFSRET 547
                 Y+  + + E+
Sbjct: 9245 QVFASYKYNITTTES 9259



 Score =  100 bits (239), Expect = 3e-19
 Identities = 124/537 (23%), Positives = 208/537 (38%), Gaps = 30/537 (5%)

Query: 2    SDDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL 61
            S+  +T  E   ++E    ++V   + ATL     GSP   ++W+K G  + S     + 
Sbjct: 7296 SEATLTVQEPARVVEPAASISVTAGESATLESTISGSPELKVKWFKDGKEMTSGRKCKMT 7355

Query: 62   PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESKQSA 120
                   ++       SD+  Y  + +N  G    + + T+    +   F        + 
Sbjct: 7356 VKDNTATMKILSAE-KSDSAEYIMQVSNKVGKDECTCSLTVLDRTMPPTFTKPLRRVDAN 7414

Query: 121  QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQ 179
             G+   L+C    GS    + W K+   +      +    D    L I    + D+G Y+
Sbjct: 7415 IGNDASLDC-KVSGSQPMTIAWFKDDHEITAGPKFQAGFKDHSATLQIAGLEKADSGVYK 7473

Query: 180  CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW---- 235
            C A N+AG +E++  TL +   P     P+      GS+V+F+    G     V W    
Sbjct: 7474 CRATNSAGFKETS-GTLYVKEPPTFTVKPDGQDVIPGSTVSFRAAFTGTAPLTVKWFKED 7532

Query: 236  RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS- 294
            +    GG   +   K     SL L  V  +D   Y+C+  N  G V  +  L V +PP+ 
Sbjct: 7533 KEIVSGGTYFI--KKDATSSSLELQAVKPSDSARYACQVSNDAGKVDCTALLFVKEPPTF 7590

Query: 295  INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
            +     +  V  G  +R  C ATG P     W  +     I PG    KY   A  D V 
Sbjct: 7591 VRKLEATTLVTCGQSSRLECRATGSPVIIFKWFKD--EMEITPG---PKY-TMAADDLVA 7644

Query: 355  VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
             L I      +S    VC A + AGS   RG +TV +    PP  + +  S   +    +
Sbjct: 7645 SLEIVQCTLAES-GDYVCVASSEAGSDCCRGTVTVKA----PPSFVRSLESKDVVKGSEL 7699

Query: 415  AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT-NDGTLVLKDL--DKSDSGTYTCVASS 471
             +    +   P  +      G+A+  + R  +T  D  + L+ L  +  D G Y C   +
Sbjct: 7700 MLEGQVSGSAPFTVTLCK-NGKAIRNDKRHRITVKDELIALQVLAVEAGDVGLYQCTVEN 7758

Query: 472  RHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNN 528
            + G+      + +  P  P+    +  ++SSL G     +        + +SW ++N
Sbjct: 7759 QVGRVSCDCHVTLKDP--PSF-VQKLENLSSLVGSEVSLLCVLKGSEPMVVSWMKDN 7812



 Score = 93.1 bits (221), Expect = 4e-17
 Identities = 120/529 (22%), Positives = 201/529 (37%), Gaps = 29/529 (5%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            E P ++    D++V     ATL+     + +  + W   G LV              + L
Sbjct: 6742 EHPTVVTALEDISVDEDSKATLSTTI--THAAKVNWLFNGQLVKPGKEFRCSKEKDTYTL 6799

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
              +        G Y CEA N  G   + +    V  +   FRL+  + +   G +    C
Sbjct: 6800 VISKVVKEMHQGEYVCEAENEAGKTTTSSRLTVVPRVPPVFRLKIAALEINVGSSAKFYC 6859

Query: 130  LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGT 188
                 +P+ N  W K+G  +      R+      + L +    + D+G Y C   N  G 
Sbjct: 6860 -EVSDAPDVNFRWYKSGVEIKQSEKYRIVSSSTSSALELVSPVKADSGEYSCKVSNPHGV 6918

Query: 189  RESAIATLKIHI-KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
               A + +   +  P  ++ PE +    G    FQC + G    DV+W +     +    
Sbjct: 6919 DTCAASLIVTELYPPVFVSKPEPMTLFVGKEAVFQCSLTGSSPMDVVWHKDNLAISSEGK 6978

Query: 248  RVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
             V   D    SL + ++ LA +G Y C+A NSVG  + S  L V D PS     +  +  
Sbjct: 6979 YVMKSDKNKYSLHIQSLELAHQGVYLCKASNSVGTATFSTELWVIDKPSFVKPFDQASAA 7038

Query: 306  SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
              +  R  C        T+ W+ +G +       S D     +  D V V+ I      D
Sbjct: 7039 VNDPVRLECQVNEDTGVTIIWTRDGKKV----HQSMD--CKLSFEDKVAVVEIPKAKLKD 7092

Query: 366  SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
            S    VC+A N AGSS     + V      PP I     + + L  K    +    I   
Sbjct: 7093 S-GKYVCTATNEAGSSSCEAVVMV----QEPPSIRKELQTVEAL--KGGPAYLEYEIAGT 7145

Query: 426  EPI-IAWYFEGEALIQNHRRNVTNDGTLVLKDL---DKSDSGTYTCVASSRHGKYVWSGA 481
             P  I W    + +  + + N+ +  +L   ++   + +D G Y  V S+  GK      
Sbjct: 7146 APFEITWSKNRKPITSDKKYNIISQQSLSRLEILTFESADVGDYQMVVSNEVGKVSTKAV 7205

Query: 482  LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTS-VTLSWSQNNK 529
              +  P  P+    R   V+++ G   K +   V  +S +T+ W ++++
Sbjct: 7206 AKLKEP--PSF-TKRVDSVTAVLGTTVK-LQGTVKGSSPITVKWMKDSE 7250



 Score = 68.5 bits (160), Expect = 1e-09
 Identities = 107/465 (23%), Positives = 179/465 (38%), Gaps = 43/465 (9%)

Query: 44   RWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH-SDAGVYWCEATNSYGTARSRNATLH 102
            +W K GV V S     +        L  T   VH  D G Y   A ++   A S N  + 
Sbjct: 2754 KWLKNGVEVKSSDRCQVRSRQLTHTL--TIRNVHFGDGGEYQFVAGSA---ATSANLFVE 2808

Query: 103  VAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG 162
              V+  EF  + +  +  +    + EC      P   V W K+GQ L    +  +   + 
Sbjct: 2809 ARVI--EFTRKIKDIKIIEKKKAIFEC--EVSEPNIQVMWMKDGQELDLSEERYVTTAEK 2864

Query: 163  --GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVT 220
                L+IQ  R +DAG Y  +A ++    +  +    I I P       D+        T
Sbjct: 2865 YVHRLMIQTVRMSDAGEYSVVAGSSVSKAQLVVEGRDIRIAP---PAERDITVLEKHRAT 2921

Query: 221  FQCRVGGDPLPDVLWRRSAGGGNMPLGR----VKVLDDGSLRLDNVILADEGEYSCEAEN 276
             +  V  D   DV  R    G  + L      V +     + +     +D GEY+  A  
Sbjct: 2922 IEFEVNED---DVEGRWLKNGAELSLEERFSYVVIRKVHRITISETFRSDAGEYTFIAGK 2978

Query: 277  SVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF 336
            +  +V+    + + +PP I       +VE G +ARF+   +G P+P + W    N  ++ 
Sbjct: 2979 NRSSVNLR--VNIPEPPQILRHMEPQSVEVGKLARFSVEVSGVPQPQVSW--YKNSQMLS 3034

Query: 337  PGMSRDKYHATAVFDGVTVLTINDTD--------KNDSRNTIVCSAVNYAGSSFVRGKLT 388
             G  + K+   A    + ++ +   D        KND       +++N   S  V   L 
Sbjct: 3035 AGF-KCKFLCEANQHSLLLIEVFPEDAAVYSCEAKNDYGAASSTASLNVEVSEVVSPDLA 3093

Query: 389  VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH--RRNV 446
                    PP+IT+  S+ +      A F C  +   +  I+W+ + + + Q+   R + 
Sbjct: 3094 AAV----APPVITSPISSTSAREGEPARFHC-RVHGDDVKISWFHKEKEIKQSEFFRMSQ 3148

Query: 447  TNDG-TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
              D   L +  +   D G Y+CVA++  G    S  L +D    P
Sbjct: 3149 FEDSCQLEISRVYPEDEGEYSCVATNSGGTASCSATLTLDGQTLP 3193



 Score = 66.9 bits (156), Expect = 3e-09
 Identities = 77/287 (26%), Positives = 113/287 (39%), Gaps = 27/287 (9%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
            D+TV     AT+            RW K G  +  +   S +    +  +  +     SD
Sbjct: 2911 DITVLEKHRATIEFEVNEDDVEG-RWLKNGAELSLEERFSYVVIRKVHRITISE-TFRSD 2968

Query: 80   AGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
            AG Y   A  +  +   R N      +LR    +EP+S +  +     +E     G P+P
Sbjct: 2969 AGEYTFIAGKNRSSVNLRVNIPEPPQILRH---MEPQSVEVGKLARFSVEV---SGVPQP 3022

Query: 139  NVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
             V W KN Q +L  G     L +    +L++ +    DA  Y C A+N  G   S  A+L
Sbjct: 3023 QVSWYKNSQ-MLSAGFKCKFLCEANQHSLLLIEVFPEDAAVYSCEAKNDYGAASST-ASL 3080

Query: 197  KIHIK------------PYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
             + +             P +IT P     A+ G    F CRV GD +    + +      
Sbjct: 3081 NVEVSEVVSPDLAAAVAPPVITSPISSTSAREGEPARFHCRVHGDDVKISWFHKEKEIKQ 3140

Query: 244  MPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
                R+   +D   L +  V   DEGEYSC A NS G  S S  LT+
Sbjct: 3141 SEFFRMSQFEDSCQLEISRVYPEDEGEYSCVATNSGGTASCSATLTL 3187



 Score = 62.9 bits (146), Expect = 5e-08
 Identities = 76/308 (24%), Positives = 118/308 (38%), Gaps = 25/308 (8%)

Query: 18   PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG---LFFLRATHG 74
            P +VT+       L C   GS    + W K    + S  + +I        L  L+A  G
Sbjct: 9500 PQEVTMG--DSIELECHMTGSAPIKVTWSKDHKDIRSGGNYNISCVDNTPHLTILKADKG 9557

Query: 75   RVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEP-ESKQSAQGDTVVLECLPP 132
                D G Y+C A N  G    S + T+        F  +P E  +  +G  V +E    
Sbjct: 9558 ----DTGKYFCHAMNDVGKVSCSSDVTVKERKNPPVFTKKPSEHMEDTEGRLVKIEGRVS 9613

Query: 133  RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
               P    ++K++ +    D        +   L I+ +  TD+GRY C A N AG R S 
Sbjct: 9614 GSQPMSVSWYKEDAEIHSSDKYDISFKSNVAVLCIKSSHVTDSGRYTCQASNEAG-RASC 9672

Query: 193  IATLKIHI--KPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGGGNMP 245
              T+ I    KP +   P + +    G  ++ +C V G     + W +       GGN  
Sbjct: 9673 CTTVGISEAKKPPVFDVPLKPLTVDEGEKMSLKCHVCGSAPLIIQWMKDRKELTSGGNTK 9732

Query: 246  LGRVKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
            +       DG+  L +      D G+Y C+A N  G+  +   + V   P   L+P    
Sbjct: 9733 IS----FTDGTACLEISPASRKDAGDYLCKATNDAGSEFSKAKVAVRQKPGAALAPAEAP 9788

Query: 304  VESGNVAR 311
              +  V R
Sbjct: 9789 AVAAPVKR 9796



 Score = 60.1 bits (139), Expect = 4e-07
 Identities = 44/129 (34%), Positives = 61/129 (47%), Gaps = 7/129 (5%)

Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM-PLGRVKV-LDDGS--LRLDNVIL 264
           + VVA  GS+ TF+ +V G P+P+V W R     ++  L  V++   DG   LRL  V  
Sbjct: 13  QSVVALEGSAATFEAQVSGSPVPEVSWFRDGQVLSVAALPGVQISFSDGRAVLRLTAVTA 72

Query: 265 ADEGEYSCEAENSVGAVSASGYLTV---YDPPSINLSPNSVNVESGNVARFTCTATGRPE 321
           A  G YS  A N  G  +++  L V     PP+      S  V  G+  R     TG P 
Sbjct: 73  AHSGRYSVRATNGAGQATSTAELLVTVETAPPNFVQRLQSSTVRQGSQVRLDVRVTGIPS 132

Query: 322 PTMFWSVEG 330
           PT+ +  EG
Sbjct: 133 PTVKFYREG 141



 Score = 59.3 bits (137), Expect = 6e-07
 Identities = 45/153 (29%), Positives = 71/153 (46%), Gaps = 4/153 (2%)

Query: 140  VYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
            V W+K+G+ +      ++   D   ++ I+    +DAGRY C   NAAG+ ES+  +L++
Sbjct: 8521 VEWQKDGKKIFSGVKHKLIQQDNSVSVEIEQLEPSDAGRYSCKLTNAAGSCESS-GSLQV 8579

Query: 199  HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-- 256
               P  ++ PE   A   + V F+    G P   V W +              LD  S  
Sbjct: 8580 KEPPSFVSPPEPQSAVPNAKVRFKGTFKGTPPFTVQWFKDDRELMTGPTCFTGLDGLSCF 8639

Query: 257  LRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
            L L +V ++  G YSC+  N+ G+   S  LTV
Sbjct: 8640 LELYSVNISQSGVYSCQVSNAAGSARCSANLTV 8672



 Score = 58.4 bits (135), Expect = 1e-06
 Identities = 67/224 (29%), Positives = 96/224 (42%), Gaps = 11/224 (4%)

Query: 8   SGEAPYIIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHR-SILPAG 64
           S +AP    QPL   VA     AT   +  GSP P + W++ G VL V+      I  + 
Sbjct: 2   STQAP-TFTQPLQSVVALEGSAATFEAQVSGSPVPEVSWFRDGQVLSVAALPGVQISFSD 60

Query: 65  GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATL-HVAVLREEFRLEPESKQSAQGD 123
           G   LR T     + +G Y   ATN  G A S    L  V      F    +S    QG 
Sbjct: 61  GRAVLRLT-AVTAAHSGRYSVRATNGAGQATSTAELLVTVETAPPNFVQRLQSSTVRQGS 119

Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCI 181
            V L+ +   G P P V + + G  +    D ++ L DG   +L+I +A   D+G Y   
Sbjct: 120 QVRLD-VRVTGIPSPTVKFYREGAEIQSSADFQI-LQDGDLYSLLIAEAFPEDSGTYSVT 177

Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV 225
           A N++G R ++ A L +  +  + T     V  T    T + RV
Sbjct: 178 AANSSG-RATSTAELLVQGEEAMPTKKTKTVVSTSEIRTSKARV 220



 Score = 58.4 bits (135), Expect = 1e-06
 Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 2/92 (2%)

Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL 259
           + P LI G ++V    G S+T +C++GG P P ++W R        +       DG  RL
Sbjct: 590 VPPTLIVGLKNVTVTEGESLTLECQIGGQPTPVIMWFREDYQIESSIDFHTSYTDGIARL 649

Query: 260 --DNVILADEGEYSCEAENSVGAVSASGYLTV 289
                   D G +SC A N  G +S S YL V
Sbjct: 650 VIREAFAEDSGRFSCTATNEAGTISTSCYLLV 681



 Score = 54.0 bits (124), Expect = 2e-05
 Identities = 72/281 (25%), Positives = 117/281 (41%), Gaps = 23/281 (8%)

Query: 218  SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEA 274
            S+TF   V G P P+V W  +     +   R+K+  DG   SL + +V  AD+GEY CEA
Sbjct: 5190 SLTFFAEVFGLPSPEVKWFCNKTQ-LVEDDRIKMERDGDSISLTVLDVTKADQGEYICEA 5248

Query: 275  ENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334
             N+VG  + S  L V     + L P    V   +V  F              S   +   
Sbjct: 5249 VNNVGE-ARSVTLVVVLSQEMRLMPPPPAVTHQHVMEFDVEDNDT-------SRSPSPQE 5300

Query: 335  IFPGMSRDKYHATAVFDGVTVLTIND-TDKNDSRNT---IVCSAVNYAGSSFV---RGKL 387
            I   +  D+         V ++TI + T  N S      ++ S        FV      L
Sbjct: 5301 ILLEVELDENEVKEFEKQVKIITIPEYTADNKSMIVSLDVLPSVYEEGAVDFVTHEHDDL 5360

Query: 388  TVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNV- 446
             +  +    PP   N   +   P  +  +F C+ + TP PI++W+   + +  N ++ V 
Sbjct: 5361 KIAFEVTEMPPRFINPICDMETPEGTTILFECSLMGTPSPIVSWFKGDKKIPPNSKKYVH 5420

Query: 447  TNDG---TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
            +++G    L +  +   DSG Y C A +  G+ +   +L+V
Sbjct: 5421 SSEGDNHILKICTVTTQDSGVYICRAINVVGETLSRASLVV 5461



 Score = 51.2 bits (117), Expect = 2e-04
 Identities = 38/116 (32%), Positives = 54/116 (46%), Gaps = 7/116 (6%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS--DTHRSILPAGGLFFL 69
           P +I    +VTV   +  TL C+ GG P+P I W++    + S  D H S         +
Sbjct: 592 PTLIVGLKNVTVTEGESLTLECQIGGQPTPVIMWFREDYQIESSIDFHTSYTDGIARLVI 651

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDT 124
           R        D+G + C ATN  GT  S +  L V V  E E+R EP ++ +  G T
Sbjct: 652 REAFA---EDSGRFSCTATNEAGTI-STSCYLLVKVSEEIEYREEPVAEVTEVGVT 703



 Score = 50.4 bits (115), Expect = 3e-04
 Identities = 32/78 (41%), Positives = 42/78 (53%), Gaps = 5/78 (6%)

Query: 216  GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG--RVKVLDDG--SLRLDNVILADEGEYS 271
            G  VTF CR+ G PLP + W +  G    P    +++ L DG  SLRL  V+  DEG Y+
Sbjct: 968  GMGVTFHCRMSGKPLPKIAWFKD-GQRLRPSDHYQMETLQDGRASLRLAQVLPEDEGVYT 1026

Query: 272  CEAENSVGAVSASGYLTV 289
              A N +G   +SG L V
Sbjct: 1027 AFAANVLGNAVSSGKLYV 1044



 Score = 48.0 bits (109), Expect = 0.002
 Identities = 31/80 (38%), Positives = 42/80 (52%), Gaps = 7/80 (8%)

Query: 216  GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL---DDGS--LRLDNVILADEGEY 270
            G+ V F  +V GDP+PDV W +  G   +  GR  V+    DGS  L L ++   D G Y
Sbjct: 5741 GTEVFFHYQVSGDPVPDVKWYK--GAFQVQPGRNCVIISNPDGSGCLSLKSLKQEDSGMY 5798

Query: 271  SCEAENSVGAVSASGYLTVY 290
             C A N+ G  S+S  L V+
Sbjct: 5799 MCRASNTFGEASSSAELAVF 5818



 Score = 47.6 bits (108), Expect = 0.002
 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 4/90 (4%)

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGGGNMPLGRVKVLDDGSL 257
           P+ +  P       G SV F+C+VGG+P P V+W+++      G    +   +   +  L
Sbjct: 740 PFFMKKPAAQKLVEGGSVVFECQVGGNPKPHVIWKKNGLPLTTGYRYRVAYKRETGECKL 799

Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYL 287
            +      D GEY+   +N  G VSAS  L
Sbjct: 800 EISMTFADDAGEYAIFVKNPHGEVSASASL 829



 Score = 47.6 bits (108), Expect = 0.002
 Identities = 119/468 (25%), Positives = 177/468 (37%), Gaps = 56/468 (11%)

Query: 15   IEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
            I +PL DVTVA  Q A L C    + +   RW K G  V    +      G +  L  T 
Sbjct: 2376 ITRPLQDVTVAESQTAVLECEVANAEAEG-RWMKEGQPVDFSENVVSEVKGAVRRLTITI 2434

Query: 74   GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
             R   D G Y  +  NS  TA   N  +    +++  R +  ++      T+ L     +
Sbjct: 2435 TR-PQDVGEYSYQVANSKTTA---NLRVEAVKIKKTLRNQTVTETQDAVFTLELTHADVK 2490

Query: 134  GSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGTRES 191
            GS      W KNG  L    D      DG   +L I++    D   Y       +     
Sbjct: 2491 GS-----QWIKNGVELQ-SSDKYEISSDGMVQSLKIRNCNTQDESVYSFKLGKLSANARL 2544

Query: 192  AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
             + T+KI      I   +DV      + +F+  +  D +P V W    G    P  R K+
Sbjct: 2545 NVETIKI------IKKTKDVTTLMDGTASFEMSLSHDDVP-VKW-MFKGAELKPSDRCKI 2596

Query: 252  LDD---GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGN 308
            L +     L L NV  ++ GEY+      VG +  S  LTV +   I       +V    
Sbjct: 2597 LRERRAHKLILQNVNSSNAGEYTA----VVGHLQCSATLTV-EALQIVKPMKDASVAETQ 2651

Query: 309  VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
             A F C  +    P+  W  +G    +   MS +K+    V   +  L I +T K+DS  
Sbjct: 2652 AATFECEVSHFNVPST-WLKDG----VEIEMS-EKFR-IVVQGKLHQLKIVNTSKDDSAE 2704

Query: 369  -TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427
             T +C      G+  V   LTV+      P +IT+   +     +    F  T     E 
Sbjct: 2705 YTFIC------GNDRVSATLTVS------PVLITSMLKDLNAQERDTITFEVTV--NHEG 2750

Query: 428  I-IAWYFEGEALIQNHRRNVTN---DGTLVLKDLDKSDSGTYTCVASS 471
            I   W   G  +  + R  V +     TL ++++   D G Y  VA S
Sbjct: 2751 ITYKWLKNGVEVKSSDRCQVRSRQLTHTLTIRNVHFGDGGEYQFVAGS 2798



 Score = 47.2 bits (107), Expect = 0.003
 Identities = 76/324 (23%), Positives = 111/324 (34%), Gaps = 47/324 (14%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            E P I+      +V   + A  +    G P P + WYK   ++ +      L       L
Sbjct: 2991 EPPQILRHMEPQSVEVGKLARFSVEVSGVPQPQVSWYKNSQMLSAGFKCKFLCEANQHSL 3050

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHV-----------AVLREEFRLEPESKQ 118
                     DA VY CEA N YG A S  A+L+V           A +       P S  
Sbjct: 3051 LLIE-VFPEDAAVYSCEAKNDYGAA-SSTASLNVEVSEVVSPDLAAAVAPPVITSPISST 3108

Query: 119  SA-QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR 177
            SA +G+     C    G      ++ K  +    +        D   L I      D G 
Sbjct: 3109 SAREGEPARFHC-RVHGDDVKISWFHKEKEIKQSEFFRMSQFEDSCQLEISRVYPEDEGE 3167

Query: 178  YQCIARNAAGTR--------------ESAIATLKIHIKPYLIT------GPEDVVAQTGS 217
            Y C+A N+ GT               E+  A  + H+   L +      G +    Q   
Sbjct: 3168 YSCVATNSGGTASCSATLTLDGQTLPEAGAAVPQWHVSTSLTSIKKAPIGQKPTFIQPIR 3227

Query: 218  SVT--------FQCRVGGDPLPDVLW----RRSAGGGNMPLGRVKVLDDGSLRLDNVILA 265
            S T        F   V G P P+V W    R      N+     +  +  +L + +    
Sbjct: 3228 SCTVAHGAVARFHACVSGMPKPEVSWFHNQRPIQPTTNVVFHFEEATNTATLIIVDAFTE 3287

Query: 266  DEGEYSCEAENSVGAVSASGYLTV 289
              G+Y+C A NS G  + S  LT+
Sbjct: 3288 HAGQYTCRAANSAGEAACSATLTI 3311



 Score = 46.4 bits (105), Expect = 0.005
 Identities = 48/197 (24%), Positives = 76/197 (38%), Gaps = 14/197 (7%)

Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII--FPGMSRDKYHATAVF 350
           P+      SV    G+ A F    +G P P + W  +G    +   PG+        +  
Sbjct: 6   PTFTQPLQSVVALEGSAATFEAQVSGSPVPEVSWFRDGQVLSVAALPGVQ------ISFS 59

Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
           DG  VL +       S    V  A N AG +    +L VT +    PP       + T+ 
Sbjct: 60  DGRAVLRLTAVTAAHSGRYSV-RATNGAGQATSTAELLVTVET--APPNFVQRLQSSTVR 116

Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTC 467
             S           P P + +Y EG  +  +    +  DG   +L++ +    DSGTY+ 
Sbjct: 117 QGSQVRLDVRVTGIPSPTVKFYREGAEIQSSADFQILQDGDLYSLLIAEAFPEDSGTYSV 176

Query: 468 VASSRHGKYVWSGALLV 484
            A++  G+   +  LLV
Sbjct: 177 TAANSSGRATSTAELLV 193



 Score = 46.0 bits (104), Expect = 0.006
 Identities = 23/71 (32%), Positives = 35/71 (49%)

Query: 256  SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315
            S+ ++ +  +D G YSC+  N+ G+  +SG L V +PPS    P   +       RF  T
Sbjct: 8546 SVEIEQLEPSDAGRYSCKLTNAAGSCESSGSLQVKEPPSFVSPPEPQSAVPNAKVRFKGT 8605

Query: 316  ATGRPEPTMFW 326
              G P  T+ W
Sbjct: 8606 FKGTPPFTVQW 8616



 Score = 44.8 bits (101), Expect = 0.015
 Identities = 33/106 (31%), Positives = 45/106 (42%), Gaps = 4/106 (3%)

Query: 9    GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
            G  P  ++  +   V  +   T      G PSP ++W+     +V D    +   G    
Sbjct: 5171 GVPPAFLKPLMKKRVCENDSLTFFAEVFGLPSPEVKWFCNKTQLVEDDRIKMERDGDSIS 5230

Query: 69   LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP 114
            L        +D G Y CEA N+ G ARS   TL V VL +E RL P
Sbjct: 5231 LTVLDV-TKADQGEYICEAVNNVGEARS--VTL-VVVLSQEMRLMP 5272



 Score = 44.0 bits (99), Expect = 0.025
 Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 2/69 (2%)

Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQ 179
           +G+++ LEC    G P P + W +    +    D      DG   LVI++A   D+GR+ 
Sbjct: 605 EGESLTLEC-QIGGQPTPVIMWFREDYQIESSIDFHTSYTDGIARLVIREAFAEDSGRFS 663

Query: 180 CIARNAAGT 188
           C A N AGT
Sbjct: 664 CTATNEAGT 672



 Score = 44.0 bits (99), Expect = 0.025
 Identities = 24/80 (30%), Positives = 36/80 (45%)

Query: 13   YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRAT 72
            + IE+P  V V     AT   + GG P P+++W KG    ++   R  +   G       
Sbjct: 9801 FFIEEPKAVRVTEKSTATFMTKVGGDPIPSVKWMKGKWRQMTHGGRISVDQKGQEAKLEI 9860

Query: 73   HGRVHSDAGVYWCEATNSYG 92
                 SD+G Y C A+N +G
Sbjct: 9861 REVTRSDSGQYRCIASNKHG 9880



 Score = 43.2 bits (97), Expect = 0.044
 Identities = 33/102 (32%), Positives = 44/102 (43%), Gaps = 8/102 (7%)

Query: 293  PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
            P I L P    V  G++ARF C  TG P P + W + G    +     R + H    +DG
Sbjct: 1572 PEIVLLPEPARVFEGDIARFRCRVTGYPAPKVNWYLNGQ---LIRKSKRYRLH----YDG 1624

Query: 353  VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394
            +  L I D    DS    V  A N  G++    KL V   +D
Sbjct: 1625 IYYLEIVDIKSYDSGEVRVV-ADNPLGTTEHTVKLEVQQKED 1665



 Score = 43.2 bits (97), Expect = 0.044
 Identities = 44/171 (25%), Positives = 72/171 (42%), Gaps = 8/171 (4%)

Query: 43   IRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLH 102
            + W K G  + S     ++       +        SDAG Y C+ TN+ G+  S  +   
Sbjct: 8521 VEWQKDGKKIFSGVKHKLIQQDNSVSVEIEQLEP-SDAGRYSCKLTNAAGSCESSGS--- 8576

Query: 103  VAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG 162
            + V      + P   QSA  +  V      +G+P   V W K+ + L+  G +    +DG
Sbjct: 8577 LQVKEPPSFVSPPEPQSAVPNAKVRFKGTFKGTPPFTVQWFKDDRELM-TGPTCFTGLDG 8635

Query: 163  GN--LVIQDARQTDAGRYQCIARNAAGT-RESAIATLKIHIKPYLITGPED 210
             +  L +     + +G Y C   NAAG+ R SA  T+K+ +      G +D
Sbjct: 8636 LSCFLELYSVNISQSGVYSCQVSNAAGSARCSANLTVKVAVLELQSAGFDD 8686



 Score = 43.2 bits (97), Expect = 0.044
 Identities = 47/211 (22%), Positives = 74/211 (35%), Gaps = 16/211 (7%)

Query: 20    DVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS 78
             D +V   + A   C      P   + WYKG   + S     I  +G    LR    +  S
Sbjct: 10008 DQSVFTGKEAEFQCEVTINYPEITLSWYKGTQKLDSSDKYDISISGDRHLLRIRRCQT-S 10066

Query: 79    DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
             D G Y         +A+       + V+  E     +     +G +  L C      P  
Sbjct: 10067 DQGNYRVVCGPHISSAK-------LTVMEAEVEKHLQDTSGKEGQSCTLSC--QLSIPNV 10117

Query: 139   NVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
                W KNG+ L   G     +      L+I D +  D GRY C  ++   + +  +   +
Sbjct: 10118 QAQWFKNGKRLEMKGKFTSEVKHKIQKLLISDLKPEDQGRYTCQYQSLESSADLWVEAEQ 10177

Query: 198   IHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228
             IH    +     ++      S TF+C V  D
Sbjct: 10178 IHFTKRI----HNIEVNERQSATFECEVSFD 10204



 Score = 42.3 bits (95), Expect = 0.078
 Identities = 27/87 (31%), Positives = 37/87 (42%), Gaps = 1/87 (1%)

Query: 107  REEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV 166
            + E  L PE  +  +GD     C    G P P V W  NGQ +      R+H      L 
Sbjct: 1571 KPEIVLLPEPARVFEGDIARFRCRVT-GYPAPKVNWYLNGQLIRKSKRYRLHYDGIYYLE 1629

Query: 167  IQDARQTDAGRYQCIARNAAGTRESAI 193
            I D +  D+G  + +A N  GT E  +
Sbjct: 1630 IVDIKSYDSGEVRVVADNPLGTTEHTV 1656



 Score = 41.1 bits (92), Expect = 0.18
 Identities = 26/82 (31%), Positives = 44/82 (53%), Gaps = 8/82 (9%)

Query: 121  QGDTVVLECLPPRGSPEPNVYWKKNGQTL------LFDGDSRMHLVDGGNLVIQDARQTD 174
            +G+ V L+C     SP P++ W  N +TL          DS+MH+    +L+I   ++ D
Sbjct: 3380 EGEPVELKC-ELVASPPPSILWFHNNKTLGKARRRRICSDSQMHM-HTTSLIIDRVKEKD 3437

Query: 175  AGRYQCIARNAAGTRESAIATL 196
            +G Y+ +A N+ G+ ES  + L
Sbjct: 3438 SGSYKVMAINSEGSAESTASLL 3459



 Score = 40.7 bits (91), Expect = 0.24
 Identities = 31/90 (34%), Positives = 45/90 (50%), Gaps = 5/90 (5%)

Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM-HLVDGG--NLV 166
           F  +P +++  +G +VV EC    G+P+P+V WKKNG  L      R+ +  + G   L 
Sbjct: 742 FMKKPAAQKLVEGGSVVFEC-QVGGNPKPHVIWKKNGLPLTTGYRYRVAYKRETGECKLE 800

Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATL 196
           I      DAG Y    +N  G   SA A+L
Sbjct: 801 ISMTFADDAGEYAIFVKNPHG-EVSASASL 829



 Score = 39.9 bits (89), Expect = 0.41
 Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 3/91 (3%)

Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG---EALIQNHRRNVTNDGTLV 453
           PP +  G  N T+         C     P P+I W+ E    E+ I  H         LV
Sbjct: 591 PPTLIVGLKNVTVTEGESLTLECQIGGQPTPVIMWFREDYQIESSIDFHTSYTDGIARLV 650

Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
           +++    DSG ++C A++  G    S  LLV
Sbjct: 651 IREAFAEDSGRFSCTATNEAGTISTSCYLLV 681



 Score = 39.1 bits (87), Expect = 0.72
 Identities = 23/88 (26%), Positives = 43/88 (48%), Gaps = 3/88 (3%)

Query: 118  QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT--DA 175
            ++ +G T++ EC    G+P P V W K  + +  +    +H  +G N +++    T  D+
Sbjct: 5381 ETPEGTTILFEC-SLMGTPSPIVSWFKGDKKIPPNSKKYVHSSEGDNHILKICTVTTQDS 5439

Query: 176  GRYQCIARNAAGTRESAIATLKIHIKPY 203
            G Y C A N  G   S  + + ++ K +
Sbjct: 5440 GVYICRAINVVGETLSRASLVVVNAKAF 5467



 Score = 39.1 bits (87), Expect = 0.72
 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 1/84 (1%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
            +T  E P I E+P  + V    P +L+C+  GSP+  ++W K G  + S     ++    
Sbjct: 8424 LTVQEPPQITEKPEVIKVTVGDPVSLDCKVTGSPALKVKWMKEGKELQSIRQHKLVFENN 8483

Query: 66   LFFLRATHGRVHSDAGVYWCEATN 89
            +  L+        D G Y  E  N
Sbjct: 8484 ISSLK-IQAAEREDEGEYILEVAN 8506



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 30/119 (25%), Positives = 45/119 (37%), Gaps = 6/119 (5%)

Query: 291  DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
            + P+ N    +  +  G    F C  +G+P P + W  +G R  + P    D Y    + 
Sbjct: 952  EQPAFNTPVKNYRIMEGMGVTFHCRMSGKPLPKIAWFKDGQR--LRPS---DHYQMETLQ 1006

Query: 351  DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409
            DG   L +      D        A N  G++   GKL V      PP   T  P+ Q +
Sbjct: 1007 DGRASLRLAQVLPED-EGVYTAFAANVLGNAVSSGKLYVEPSGAFPPQRYTAQPAVQRI 1064



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 22/86 (25%), Positives = 34/86 (39%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P  I    D+           C   G+PSP + W+KG   +  ++ + +  + G   +  
Sbjct: 5371 PRFINPICDMETPEGTTILFECSLMGTPSPIVSWFKGDKKIPPNSKKYVHSSEGDNHILK 5430

Query: 72   THGRVHSDAGVYWCEATNSYGTARSR 97
                   D+GVY C A N  G   SR
Sbjct: 5431 ICTVTTQDSGVYICRAINVVGETLSR 5456



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 25/78 (32%), Positives = 40/78 (51%), Gaps = 9/78 (11%)

Query: 34   RAGGSPSPAIRWYKGGVLVVSDTHRSIL--PAG-GLFFLRATHGRVHSDAGVYWCEATNS 90
            +  G P P ++WYKG   V    +  I+  P G G   L++       D+G+Y C A+N+
Sbjct: 5749 QVSGDPVPDVKWYKGAFQVQPGRNCVIISNPDGSGCLSLKSLK---QEDSGMYMCRASNT 5805

Query: 91   YGTARSRNATLHVAVLRE 108
            +G A S   +  +AV +E
Sbjct: 5806 FGEASS---SAELAVFKE 5820



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 5/105 (4%)

Query: 386  KLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEAL--IQNH 442
            +L VT+ +        N P      ++ M V F C     P P IAW+ +G+ L    ++
Sbjct: 941  ELMVTAAEGEAEQPAFNTPVKNYRIMEGMGVTFHCRMSGKPLPKIAWFKDGQRLRPSDHY 1000

Query: 443  RRNVTNDG--TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485
            +     DG  +L L  +   D G YT  A++  G  V SG L V+
Sbjct: 1001 QMETLQDGRASLRLAQVLPEDEGVYTAFAANVLGNAVSSGKLYVE 1045



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 56/219 (25%), Positives = 81/219 (36%), Gaps = 34/219 (15%)

Query: 8    SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--------------- 52
            S EAP I+E+    TVA         R  G P P  +W+K G+LV               
Sbjct: 1804 SMEAPRILERIQSKTVAPMDEVRFRVRVVGRPEPECQWFKNGILVEKTERVYWFWPEDNV 1863

Query: 53   ---------VSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103
                       D+   ++ A  +    ++H  +         + T   G+  S    L  
Sbjct: 1864 CELVIRDVTAEDSASIMVKANNVAGEASSHAFLLVQGNAMLQDDTRCAGSCVSLPGFLIA 1923

Query: 104  AVLREEFRLEPESKQSAQGDTVV-LECLPPRGSPEPNVYWKKNGQTLLFDGDS-RMH--- 158
            A     F    E   + + DT+V  EC      P   V W KN  T +F GD  RMH   
Sbjct: 1924 AKAAVSFTQHLEDATANEKDTMVTFEC--ETSEPFIKVKWLKN-NTEIFSGDKYRMHSDR 1980

Query: 159  LVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
             V   +++I D R  D   Y C+  +    R SA  T++
Sbjct: 1981 KVHFLSVLIIDLR--DDAEYTCVLADDESVRTSARLTVE 2017



 Score = 37.1 bits (82), Expect = 2.9
 Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 4/100 (4%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P I+  P    V     A   CR  G P+P + WY  G L +  + R  L   G+++L  
Sbjct: 1572 PEIVLLPEPARVFEGDIARFRCRVTGYPAPKVNWYLNGQL-IRKSKRYRLHYDGIYYLEI 1630

Query: 72   THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR 111
               + + D+G     A N  GT       L V   +E+FR
Sbjct: 1631 VDIKSY-DSGEVRVVADNPLGTT-EHTVKLEVQ-QKEDFR 1667



 Score = 37.1 bits (82), Expect = 2.9
 Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 7/85 (8%)

Query: 210  DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL-----DDGSLRLDNVIL 264
            D+    G+++ F+C + G P P V W +  G   +P    K +     D+  L++  V  
Sbjct: 5379 DMETPEGTTILFECSLMGTPSPIVSWFK--GDKKIPPNSKKYVHSSEGDNHILKICTVTT 5436

Query: 265  ADEGEYSCEAENSVGAVSASGYLTV 289
             D G Y C A N VG   +   L V
Sbjct: 5437 QDSGVYICRAINVVGETLSRASLVV 5461



 Score = 36.7 bits (81), Expect = 3.9
 Identities = 25/107 (23%), Positives = 45/107 (42%), Gaps = 7/107 (6%)

Query: 385  GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR 444
            G  + TS      P  T     Q++         C  + +P P I W+   + L +  RR
Sbjct: 3354 GCSSTTSGTGNVKPSFTKKLKFQSVLEGEPVELKCELVASPPPSILWFHNNKTLGKARRR 3413

Query: 445  NVTNDG-------TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
             + +D        +L++  + + DSG+Y  +A +  G    + +LLV
Sbjct: 3414 RICSDSQMHMHTTSLIIDRVKEKDSGSYKVMAINSEGSAESTASLLV 3460



 Score = 36.3 bits (80), Expect = 5.1
 Identities = 21/81 (25%), Positives = 34/81 (41%), Gaps = 3/81 (3%)

Query: 411  IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTC 467
            +  M+ F C     P P + W  +G  L  N   ++    N   L +        GTY C
Sbjct: 4364 VGEMSEFTCQFHGDPLPTVTWLKDGHPLTNNPDFDIIDRANRSKLTVFYPTADHEGTYDC 4423

Query: 468  VASSRHGKYVWSGALLVDSPI 488
            + +++HGK + S  L +   I
Sbjct: 4424 IITNKHGKSLCSATLEIADKI 4444



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 25/89 (28%), Positives = 38/89 (42%), Gaps = 7/89 (7%)

Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
           PP++ +   +V V  G      C   G+P P + W  E      +   S   +H T+  D
Sbjct: 591 PPTLIVGLKNVTVTEGESLTLECQIGGQPTPVIMWFRED-----YQIESSIDFH-TSYTD 644

Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGS 380
           G+  L I +    DS     C+A N AG+
Sbjct: 645 GIARLVIREAFAEDS-GRFSCTATNEAGT 672



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 23/101 (22%), Positives = 41/101 (40%), Gaps = 2/101 (1%)

Query: 4    DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
            D    G AP  +++   +     + +   C+  G P P + W K G  + ++    I+  
Sbjct: 4343 DAAAGGAAPVFVKEMCPLKARVGEMSEFTCQFHGDPLPTVTWLKDGHPLTNNPDFDIIDR 4402

Query: 64   GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA 104
                 L   +     + G Y C  TN +G +   +ATL +A
Sbjct: 4403 ANRSKLTVFYPTADHE-GTYDCIITNKHGKSLC-SATLEIA 4441



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 3/45 (6%)

Query: 6    VTSGEAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGG 49
            VT     +II  PL ++T A   P  L C   G+P+P   WYK G
Sbjct: 5577 VTESPPKFII--PLTNITAAAGTPVILQCLVSGTPNPTAEWYKDG 5619



 Score = 35.5 bits (78), Expect = 8.9
 Identities = 25/68 (36%), Positives = 30/68 (44%), Gaps = 2/68 (2%)

Query: 30   TLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
            T +CR  G P P I W+K G  L  SD ++      G   LR     +  D GVY   A 
Sbjct: 972  TFHCRMSGKPLPKIAWFKDGQRLRPSDHYQMETLQDGRASLRLAQ-VLPEDEGVYTAFAA 1030

Query: 89   NSYGTARS 96
            N  G A S
Sbjct: 1031 NVLGNAVS 1038


>UniRef50_Q8WZ42 Cluster: Titin; n=65; Eukaryota|Rep: Titin - Homo
            sapiens (Human)
          Length = 34350

 Score =  141 bits (342), Expect = 9e-32
 Identities = 138/492 (28%), Positives = 199/492 (40%), Gaps = 32/492 (6%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            E PY IE    V     +PATL C+  G+P   I WYK    + S     +     +  L
Sbjct: 7945 EPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASL 8004

Query: 70   RATHGRVHSDAGVYWCEATNSYGT-ARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
               +   HSD G Y C+A NS G  A S    +    L   F  + +      G  V  E
Sbjct: 8005 -VINKVDHSDVGEYSCKADNSVGAVASSAVLVIKERKLPPFFARKLKDVHETLGFPVAFE 8063

Query: 129  CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAG 187
            C    GS    V W K+G  L  D + +   V     L I    Q+  G+Y C A N  G
Sbjct: 8064 CRI-NGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLG 8122

Query: 188  TRES-AIATLKIH-IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGG 241
            T  S A   L  H + P+    P  V    G S TF+C V G     + W    R    G
Sbjct: 8123 TASSSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPG 8182

Query: 242  GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSP 299
            GN  +  V+  +  +L +  V   D G+Y+C A N  G  S S +L V +PP     L P
Sbjct: 8183 GNYKMTLVE--NTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAHLGVQEPPRFIKKLEP 8240

Query: 300  NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
            + + V+     R+ C   G PE  + W  +             K+  + V D V VL ++
Sbjct: 8241 SRI-VKQDEFTRYECKIGGSPEIKVLWYKDETEI-----QESSKFRMSFV-DSVAVLEMH 8293

Query: 360  DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FP 418
            +    DS     C A N AGS+     L V     + PPI    P +    +K   V   
Sbjct: 8294 NLSVEDS-GDYTCEAHNAAGSASSSTSLKV-----KEPPIFRKKP-HPIETLKGADVHLE 8346

Query: 419  CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLV---LKDLDKSDSGTYTCVASSRHGK 475
            C    TP   ++WY +   L    +  + ++  L    + ++D +D G Y C A++  G 
Sbjct: 8347 CELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGS 8406

Query: 476  YVWSGALLVDSP 487
                G++ + +P
Sbjct: 8407 DTCVGSIALKAP 8418



 Score =  138 bits (334), Expect = 9e-31
 Identities = 117/463 (25%), Positives = 193/463 (41%), Gaps = 23/463 (4%)

Query: 33   CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
            C+ GGSP   + WYK    +   +   +     +  L   H     D+G Y CEA N+ G
Sbjct: 8254 CKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEM-HNLSVEDSGDYTCEAHNAAG 8312

Query: 93   TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFD 152
            +A S + +L V      FR +P   ++ +G  V LEC   +G+P  +V W K+ + L   
Sbjct: 8313 SASS-STSLKVKE-PPIFRKKPHPIETLKGADVHLEC-ELQGTPPFHVSWYKDKRELR-S 8368

Query: 153  GDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED 210
            G     + +    ++ I +    D G YQC A N  G+ ++ + ++ +   P  +    D
Sbjct: 8369 GKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGS-DTCVGSIALKAPPRFVKKLSD 8427

Query: 211  VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL---DDGSLRLDNVILADE 267
            +    G  V  Q  + G     V+W +  G        + +    +  +L+   V  A+ 
Sbjct: 8428 ISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANA 8487

Query: 268  GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327
            G+Y+C+ +N  G       L+V +P +I   P S+ V +G+     CT  G PE +  W 
Sbjct: 8488 GKYTCQIKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWF 8547

Query: 328  VEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387
             +G        ++ D  +  + F+ V+ L I +   +DS         N  G       L
Sbjct: 8548 KDGKE------LTSDNKYKISFFNKVSGLKIINVAPSDS-GVYSFEVQNPVGKDSCTASL 8600

Query: 388  TVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT 447
             V+  D   PP  T           S  V  C    +P   ++W+ EG  +    +   T
Sbjct: 8601 QVS--DRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTT 8658

Query: 448  ---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
               N   L +  L++SDSG YTC+A++  G    S  L V  P
Sbjct: 8659 LTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREP 8701



 Score =  138 bits (334), Expect = 9e-31
 Identities = 136/536 (25%), Positives = 219/536 (40%), Gaps = 30/536 (5%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
            +T  E P  +++P  + V      T      G+P  ++ W+KG   +V     ++     
Sbjct: 8696 LTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDS 8755

Query: 66   LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV-LREEFRLEPESKQSAQGDT 124
            +  L        S +G Y C  +N  G A   + T H+ +    +F          +G  
Sbjct: 8756 VAELELFDVDT-SQSGEYTCIVSNEAGKA---SCTTHLYIKAPAKFVKRLNDYSIEKGKP 8811

Query: 125  VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIAR 183
            ++LE     G+P  +V WKKNG  +       +   +    L I  +   DAG+Y C   
Sbjct: 8812 LILEG-TFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIE 8870

Query: 184  NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
            NA+G ++S  A + I   PY +   E V    G S + QC++ G P   V W +  G   
Sbjct: 8871 NASG-KDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYK--GDTK 8927

Query: 244  M-PLGRVKV---LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSIN 296
            + P    K+    +  +L  + V + D GEY C+AENSVG VSAS +LTV +   PPS +
Sbjct: 8928 LRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFS 8987

Query: 297  LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
                 V    G    F C  +G    ++ W  +G      P +       T+  D    L
Sbjct: 8988 RQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQ------TSFLDNTATL 9041

Query: 357  TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416
             I  TD++       C+A N  GS+    +L +T  + + PP      +     +   A 
Sbjct: 9042 NIFKTDRS-LAGQYSCTATNPIGSASSSARLILT--EGKNPPFFDIRLAPVDAVVGESAD 9098

Query: 417  FPCTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRH 473
            F C    T    ++W  +   +    +  ++   N   L +  +DK DSG YTC A +  
Sbjct: 9099 FECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEV 9158

Query: 474  GKYVWSGALLVDSPINPNIHFFRAAD-VSSLPGPPTKPITHNVTDTSVTLSWSQNN 528
            GK   +  L +   + P     R ++ V    G   K          +T++W +NN
Sbjct: 9159 GKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNN 9214



 Score =  137 bits (332), Expect = 1e-30
 Identities = 133/499 (26%), Positives = 208/499 (41%), Gaps = 38/499 (7%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
            V++ E PY + +   +  A     +L C+  G+P   + WYKG      DT     P   
Sbjct: 7000 VSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKG------DTKLRPTPEYR 7053

Query: 66   LFFLR--AT--HGRVH-SDAGVYWCEATNSYGTARSRNA-TLHVAVLREEFRLEPESKQS 119
             +F    AT    +V+ +D+G Y C+A NS GTA S+    +    L   F  + +  + 
Sbjct: 7054 TYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQ 7113

Query: 120  AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRY 178
              G  V L C    GS    V W ++G  L  D + +   VD    L I     + +G+Y
Sbjct: 7114 TVGLPVTLTCRL-NGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQY 7172

Query: 179  QCIARNAAGTRESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
             C A N  GT  S+        K  P+    P  +    G S  F+C V G     + W 
Sbjct: 7173 SCSASNPLGTASSSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWS 7232

Query: 237  RS----AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
            +       GGN  +  V   +   LR+  V   D G+Y+C+A N VG    S  L+V +P
Sbjct: 7233 KDNKEIRPGGNYTITCVG--NTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEP 7290

Query: 293  PS-INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
            P  +     S   + G   +  C  +G PE  + W    N + +       KY+ + + +
Sbjct: 7291 PKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWF--RNDSELHESW---KYNMSFI-N 7344

Query: 352  GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
             V +LTIN+    DS    +C A N  G +     LTV     + PP+ T  PS      
Sbjct: 7345 SVALLTINEASAEDS-GDYICEAHNGVGDASCSTALTV-----KAPPVFTQKPSPVGALK 7398

Query: 412  KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN---DGTLVLKDLDKSDSGTYTCV 468
             S  +  C    TP   + W  + + +  + +  +T+   D +L + +L+ SD G Y C 
Sbjct: 7399 GSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCK 7458

Query: 469  ASSRHGKYVWSGALLVDSP 487
            A++  G    S ++    P
Sbjct: 7459 ATNEVGSDTCSCSVKFKEP 7477



 Score =  137 bits (332), Expect = 1e-30
 Identities = 136/532 (25%), Positives = 214/532 (40%), Gaps = 32/532 (6%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            E   I+E+P  + V      TL C   G+P  + +W+K G  + SD    I     +  L
Sbjct: 8511 EPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGL 8570

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGDTVVL 127
            +  +    SD+GVY  E  N  G   S  A+L V+   +   F  + +      G +VV+
Sbjct: 8571 KIIN-VAPSDSGVYSFEVQNPVG-KDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVM 8628

Query: 128  ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAA 186
            EC    GSP  +V W   G  +      +  L D    L +    ++D+G Y CIA N A
Sbjct: 8629 EC-KVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMA 8687

Query: 187  GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
            G+ E + A L +   P  +  P+ +   TG++VTF   V G P   V W + +    +P 
Sbjct: 8688 GSDECS-APLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGS-SELVPG 8745

Query: 247  GRVKV-LDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
             R  V L+D    L L +V  +  GEY+C   N  G  S + +L +  P       N  +
Sbjct: 8746 DRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYS 8805

Query: 304  VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
            +E G       T TG P  ++ W   G         +      +A+ + +   T+ D  +
Sbjct: 8806 IEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILE-IPSSTVEDAGQ 8864

Query: 364  NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
             +      C   N +G      ++ +       PP          + +   A   C    
Sbjct: 8865 YN------CYIENASGKDSCSAQILILE-----PPYFVKQLEPVKVSVGDSASLQCQLAG 8913

Query: 424  TPEPIIAWYFEGEALI------QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
            TPE  ++WY +G+  +      + H RN  N  TLV   +D +DSG Y C A +  G+  
Sbjct: 8914 TPEIGVSWY-KGDTKLRPTTTYKMHFRN--NVATLVFNQVDINDSGEYICKAENSVGEVS 8970

Query: 478  WSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
             S  L V     P     +  DV    G P            +++SW ++ K
Sbjct: 8971 ASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGK 9022



 Score =  127 bits (307), Expect = 2e-27
 Identities = 127/507 (25%), Positives = 203/507 (40%), Gaps = 24/507 (4%)

Query: 31   LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
            + C+  GSP  ++ W+  G  + S              L   +    SD+G Y C ATN 
Sbjct: 8628 MECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCAL-TVNMLEESDSGDYTCIATNM 8686

Query: 91   YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
             G+    +A L V      F  +P+      G  V    +  +G+P  +V W K    L+
Sbjct: 8687 AGSDEC-SAPLTVRE-PPSFVQKPDPMDVLTGTNVTFTSIV-KGTPPFSVSWFKGSSELV 8743

Query: 151  FDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
                  + L D    L + D   + +G Y CI  N AG + S    L I      +    
Sbjct: 8744 PGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAG-KASCTTHLYIKAPAKFVKRLN 8802

Query: 210  DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD---DGSLRLDNVILAD 266
            D   + G  +  +    G P   V W+++ G    P  R  +        L + +  + D
Sbjct: 8803 DYSIEKGKPLILEGTFTGTPPISVTWKKN-GINVTPSQRCNITTTEKSAILEIPSSTVED 8861

Query: 267  EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326
             G+Y+C  EN+ G  S S  + + +PP        V V  G+ A   C   G PE  + W
Sbjct: 8862 AGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSW 8921

Query: 327  SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
              +G+ T + P  +  K H     + V  L  N  D NDS    +C A N  G   V   
Sbjct: 8922 -YKGD-TKLRP-TTTYKMHFR---NNVATLVFNQVDINDS-GEYICKAENSVGE--VSAS 8972

Query: 387  LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGEALIQNHRRN 445
              +T  + + PP  +    +    +    VF C AI   EPI ++WY +G+ L  +    
Sbjct: 8973 TFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDC-AISGSEPISVSWYKDGKPLKDSPNVQ 9031

Query: 446  VT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSS 502
             +   N  TL +   D+S +G Y+C A++  G    S  L++    NP     R A V +
Sbjct: 9032 TSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDA 9091

Query: 503  LPGPPTKPITHNVTDTSVTLSWSQNNK 529
            + G       H      + +SW+++++
Sbjct: 9092 VVGESADFECHVTGTQPIKVSWAKDSR 9118



 Score =  124 bits (298), Expect = 2e-26
 Identities = 129/507 (25%), Positives = 210/507 (41%), Gaps = 26/507 (5%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            E   IIE+P  +TV    P  L C   G+P  + +W+K G  + +D+   I     +  L
Sbjct: 7570 EPARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASL 7629

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGDTVVL 127
            +     + SD G+Y  E  NS G +     ++HV+  ++   F  + +   +  G +VVL
Sbjct: 7630 KIPCAEM-SDKGLYSFEVKNSVGKSNC-TVSVHVSDRIVPPSFIRKLKDVNAILGASVVL 7687

Query: 128  ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAA 186
            EC    GS   +V W ++G  ++     +    +    L +     +D G Y C+A N A
Sbjct: 7688 ECRVS-GSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVA 7746

Query: 187  GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
            G+ E + A L +   P     P+ V    G S+TF   + G P   V W + +    +P 
Sbjct: 7747 GSDECS-AVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRE-LVPG 7804

Query: 247  GRVKV-LDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
                + L+D    L L  V   + G+YSC   N  G+ S + +L V +P +        +
Sbjct: 7805 ESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLADFS 7864

Query: 304  VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
            VE+G+      T TG P  ++ W ++    I     S+ +  +  + +  T+L I ++  
Sbjct: 7865 VETGSPIVLEATYTGTPPISVSW-IKDEYLI-----SQSERCSITMTEKSTILEILESTI 7918

Query: 364  NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
             D      C   N AG       ++V       PP       +    I   A   C    
Sbjct: 7919 EDYAQ-YSCLIENEAGQDICEALVSVLE-----PPYFIEPLEHVEAVIGEPATLQCKVDG 7972

Query: 424  TPEPIIAWYFEGEAL--IQNHRRNVTND-GTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
            TPE  I+WY E   L     ++    N+  +LV+  +D SD G Y+C A +  G    S 
Sbjct: 7973 TPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSA 8032

Query: 481  ALLVDSPINPNIHFFRAADVSSLPGPP 507
             L++     P     +  DV    G P
Sbjct: 8033 VLVIKERKLPPFFARKLKDVHETLGFP 8059



 Score =  122 bits (293), Expect = 8e-26
 Identities = 124/467 (26%), Positives = 186/467 (39%), Gaps = 30/467 (6%)

Query: 31   LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
            L C   GS   +I+W+K    + +             FL  +     +D+G Y C ATN 
Sbjct: 5621 LECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLE-GTDSGTYTCSATNK 5679

Query: 91   YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
             G       + H+ V    + +E    Q    +T V       G+    + W K+ + L 
Sbjct: 5680 AG---HNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKEL- 5735

Query: 151  FDGDSRMHLVD--GGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208
              G +R    D    +L +  A+ TD+G Y C   N  GT  S  ATL +   P  I  P
Sbjct: 5736 HSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSK-ATLFVKEPPQFIKKP 5794

Query: 209  EDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN-MPLGRVKVLDD-GSLRLDNVILA 265
              V V + G S TF+C++ G P   V W         +    +  +D   + ++    + 
Sbjct: 5795 SPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVE 5854

Query: 266  DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325
            + G Y CEA N  G  S S  L V +PP+       V V   +     C  TG P   + 
Sbjct: 5855 NSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVT 5914

Query: 326  WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT--DKNDSRNTIVCSAVNYAGSSFV 383
            W ++ NR I     S  KY  T   D V+V  ++ T  D +D+     C   N  GS   
Sbjct: 5915 W-LKNNREI----RSSKKYTLT---DRVSVFNLHITKCDPSDT-GEYQCIVSNEGGSCSC 5965

Query: 384  RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN-- 441
              ++ +     + PP       N T  +KS A F  T   +P   I W  + + L ++  
Sbjct: 5966 STRVAL-----KEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDN 6020

Query: 442  -HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
             +   V +  TL ++ +D   SG YTC A +  G       LLV  P
Sbjct: 6021 VYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEP 6067



 Score =  122 bits (293), Expect = 8e-26
 Identities = 127/492 (25%), Positives = 206/492 (41%), Gaps = 25/492 (5%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
            +T  E P   + P  V V      T      G+P   ++W+KG   +V     +I     
Sbjct: 7755 LTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDF 7814

Query: 66   LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDT 124
            +  L     +   ++G Y C  TN  G+A   + T H+ V      ++  +  S + G  
Sbjct: 7815 VTELELFEVQP-LESGDYSCLVTNDAGSA---SCTTHLFVKEPATFVKRLADFSVETGSP 7870

Query: 125  VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIAR 183
            +VLE     G+P  +V W K+   +       + + +   ++ I ++   D  +Y C+  
Sbjct: 7871 IVLEATYT-GTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLIE 7929

Query: 184  NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW-RRSAGGG 242
            N AG ++   A + +   PY I   E V A  G   T QC+V G P   + W +      
Sbjct: 7930 NEAG-QDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLR 7988

Query: 243  NMPLGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLS 298
            + P  +++  ++  SL ++ V  +D GEYSC+A+NSVGAV++S  L + +   PP     
Sbjct: 7989 SAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKERKLPPFFARK 8048

Query: 299  PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
               V+   G    F C   G     + W  +G   ++   +  D    T+    V  L I
Sbjct: 8049 LKDVHETLGFPVAFECRINGSEPLQVSWYKDG---VL---LKDDANLQTSFVHNVATLQI 8102

Query: 359  NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
              TD++       CSA N  G++    KL ++  +   PP     P +  L +     F 
Sbjct: 8103 LQTDQSHI-GQYNCSASNPLGTASSSAKLILS--EHEVPPFFDLKPVSVDLALGESGTFK 8159

Query: 419  CTAICTPEPIIAWYFEGEALIQ--NHRRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
            C    T    I W  +   +    N++   V N  TL +  + K D+G YTC AS+  GK
Sbjct: 8160 CHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGK 8219

Query: 476  YVWSGALLVDSP 487
               S  L V  P
Sbjct: 8220 DSCSAHLGVQEP 8231



 Score =  121 bits (292), Expect = 1e-25
 Identities = 125/497 (25%), Positives = 190/497 (38%), Gaps = 29/497 (5%)

Query: 5    YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
            ++T  E PY +E+P    V  +    L    GG+    I+W+K    + S   RS+    
Sbjct: 5688 HLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDD 5747

Query: 65   GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
                L     +  +D+G Y C+ +N  GTA S+ ATL V    +  +          G +
Sbjct: 5748 TSTSLELFAAKA-TDSGTYICQLSNDVGTATSK-ATLFVKEPPQFIKKPSPVLVLRNGQS 5805

Query: 125  VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIAR 183
               EC    G+P+  V W  +G  +       +  +DG     I  AR  ++G Y C AR
Sbjct: 5806 TTFEC-QITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEAR 5864

Query: 184  NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSA 239
            N AGT   +I  LK+   P  I   + V     S V  +C V G P  +V W    R   
Sbjct: 5865 NDAGTASCSI-ELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIR 5923

Query: 240  GGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
                  L  RV V    +L +     +D GEY C   N  G+ S S  + + +PPS    
Sbjct: 5924 SSKKYTLTDRVSVF---NLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKK 5980

Query: 299  PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
              +      + A F  T  G P  ++ W  +         +  D     +  D V  L I
Sbjct: 5981 IENTTTVLKSSATFQSTVAGSPPISITWLKDDQI------LDEDDNVYISFVDSVATLQI 6034

Query: 359  NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
               D N       C A N +G       L V      P  I+    S      K      
Sbjct: 6035 RSVD-NGHSGRYTCQAKNESGVERCYAFLLV----QEPAQIVEKAKSVDVTE-KDPMTLE 6088

Query: 419  CTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGK 475
            C    TPE  + W  +G+ ++ +   +++   N  +  ++ + K DSG YT    +  G 
Sbjct: 6089 CVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGS 6148

Query: 476  YVWSGAL-LVDSPINPN 491
                  L ++D  I P+
Sbjct: 6149 SSCDAYLRVLDQNIPPS 6165



 Score =  121 bits (291), Expect = 1e-25
 Identities = 124/492 (25%), Positives = 205/492 (41%), Gaps = 25/492 (5%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
            +T  E P  +++P  + V   +  T      G+P   + W++G   +V     +I     
Sbjct: 6814 LTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDT 6873

Query: 66   LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDT 124
            +  L   +  + S +G Y C  +N+ G A   + T  + V      L+  S  S + G +
Sbjct: 6874 VAELELFNIDI-SQSGEYTCVVSNNAGQA---SCTTRLFVKEPAAFLKRLSDHSVEPGKS 6929

Query: 125  VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIAR 183
            ++LE     G+   +V WKK+G  +       +   +   ++ I ++ + DAG+Y C   
Sbjct: 6930 IILES-TYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIE 6988

Query: 184  NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW-RRSAGGG 242
            N AG R+   A +     PY +T  E + A  G SV+ QC+V G P   V W +      
Sbjct: 6989 NEAG-RDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLR 7047

Query: 243  NMPLGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLS 298
              P  R    ++  +L  + V + D GEY+C+AENS+G  S+     + +   PPS    
Sbjct: 7048 PTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQ 7107

Query: 299  PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
               +    G     TC   G     + W  +G   ++   +  D+   T+  D V  L I
Sbjct: 7108 LKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDG---VL---LRDDENLQTSFVDNVATLKI 7161

Query: 359  NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
              TD + S     CSA N  G++    +L  T+ + +  P     P +  +     A F 
Sbjct: 7162 LQTDLSHS-GQYSCSASNPLGTASSSARL--TAREPKKSPFFDIKPVSIDVIAGESADFE 7218

Query: 419  CTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGK 475
            C         I W  + + +       +T   N   L +  + K DSG YTC A++  GK
Sbjct: 7219 CHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGK 7278

Query: 476  YVWSGALLVDSP 487
             + S  L V  P
Sbjct: 7279 DMCSAQLSVKEP 7290



 Score =  117 bits (281), Expect = 2e-24
 Identities = 125/490 (25%), Positives = 212/490 (43%), Gaps = 35/490 (7%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAGGLFFLR 70
            P  +++  D++    +   L     G+   ++ W+K  G +V    +  I  +  +  L+
Sbjct: 8419 PRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQ 8478

Query: 71   ATHGRVH-SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLE 128
             +  RV  ++AG Y C+  N  G      ATL  +VL     +E PES +   GDT  LE
Sbjct: 8479 FS--RVEPANAGKYTCQIKNDAGMQECF-ATL--SVLEPATIVEKPESIKVTTGDTCTLE 8533

Query: 129  CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAG 187
            C    G+PE +  W K+G+ L  D   ++   +    L I +   +D+G Y    +N  G
Sbjct: 8534 CTVA-GTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVG 8592

Query: 188  TRESAIATLKIH---IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
             ++S  A+L++    + P      ++    +GSSV  +C+V G P   V W     G  +
Sbjct: 8593 -KDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHE--GNEI 8649

Query: 245  PLGRV--KVLDDGSLRLDNVIL--ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
              GR     L D +  L   +L  +D G+Y+C A N  G+   S  LTV +PPS    P+
Sbjct: 8650 SSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPD 8709

Query: 301  SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
             ++V +G    FT    G P  ++ W  +G+  ++ PG   D+ +  ++ D V  L + D
Sbjct: 8710 PMDVLTGTNVTFTSIVKGTPPFSVSW-FKGSSELV-PG---DRCN-VSLEDSVAELELFD 8763

Query: 361  TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
             D + S     C   N AG +     L +     + P       ++ ++      +   T
Sbjct: 8764 VDTSQS-GEYTCIVSNEAGKASCTTHLYI-----KAPAKFVKRLNDYSIEKGKPLILEGT 8817

Query: 421  AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS---DSGTYTCVASSRHGKYV 477
               TP   + W   G  +  + R N+T      + ++  S   D+G Y C   +  GK  
Sbjct: 8818 FTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDS 8877

Query: 478  WSGALLVDSP 487
             S  +L+  P
Sbjct: 8878 CSAQILILEP 8887



 Score =  116 bits (280), Expect = 3e-24
 Identities = 114/486 (23%), Positives = 190/486 (39%), Gaps = 22/486 (4%)

Query: 10   EAPYIIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
            E P  +++     VA+  +   L C+  GSP   + W++    +      ++     +  
Sbjct: 7289 EPPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVAL 7348

Query: 69   LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
            L         D+G Y CEA N  G A    A    A     F  +P    + +G  V+L+
Sbjct: 7349 LTINEASAE-DSGDYICEAHNGVGDASCSTALTVKAP--PVFTQKPSPVGALKGSDVILQ 7405

Query: 129  CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAG 187
            C    G+P   V W K+ + +      ++       +L I +   +D G Y C A N  G
Sbjct: 7406 C-EISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVG 7464

Query: 188  TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMP 245
            + ++   ++K    P  +    D     G +V  +  V G     V+W +  G       
Sbjct: 7465 S-DTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESE 7523

Query: 246  LGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
              R+  +D+  +L+L +   ++ G+Y C+ +N  G    S  LTV +P  I   P  + V
Sbjct: 7524 NTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEPMTV 7583

Query: 305  ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
             +GN     C  TG PE +  W  +G        +S D  H     + V  L I   + +
Sbjct: 7584 TTGNPFALECVVTGTPELSAKWFKDGRE------LSADSKHHITFINKVASLKIPCAEMS 7637

Query: 365  DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
            D +        N  G S     ++V   D   PP       +    + +  V  C    +
Sbjct: 7638 D-KGLYSFEVKNSVGKS--NCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGS 7694

Query: 425  PEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
                + W+ +G  ++   +   +   N  TL L  L+ SD+G YTCVA++  G    S  
Sbjct: 7695 APISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAV 7754

Query: 482  LLVDSP 487
            L V  P
Sbjct: 7755 LTVQEP 7760



 Score =  115 bits (277), Expect = 7e-24
 Identities = 125/481 (25%), Positives = 192/481 (39%), Gaps = 30/481 (6%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            E PY ++Q   V V+    A+L C+  G+P   + WYKG   +   T   +     +  L
Sbjct: 8886 EPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATL 8945

Query: 70   RATHGRVHSDAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
                  + +D+G Y C+A NS G  + S   T+    L   F  +    Q   G  VV +
Sbjct: 8946 VFNQVDI-NDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFD 9004

Query: 129  CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAG 187
            C    GS   +V W K+G+ L    + +   +D    L I    ++ AG+Y C A N  G
Sbjct: 9005 C-AISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIG 9063

Query: 188  TRESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGG 241
            +  S+   +    K  P+       V A  G S  F+C V G     V W    R    G
Sbjct: 9064 SASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSG 9123

Query: 242  GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLS 298
            G   +  ++  +   L +  V   D G+Y+C A N VG  S +  L + +   PPS    
Sbjct: 9124 GKYQISYLE--NSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKR 9181

Query: 299  -PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
               +V    GN  +      G    T+ W    N   I P  + +        +   VL 
Sbjct: 9182 LSETVEETEGNSFKLEGRVAGSQPITVAW--YKNNIEIQPTSNCE----ITFKNNTLVLQ 9235

Query: 358  INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
            +     ND+     C   N AGS+     + +   + + PP+     +  T+        
Sbjct: 9236 VRKAGMNDA-GLYTCKVSNDAGSALCTSSIVI--KEPKKPPVFDQHLTPVTVSEGEYVQL 9292

Query: 418  PCTAICTPEPI-IAWYFEGEALIQNHRRNVT-NDGTLV--LKDLDKSDSGTYTCVASSRH 473
             C  +   EPI I W   G  +  + R + +   GT V  L+D+ K+DSG Y C AS+  
Sbjct: 9293 SC-HVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVA 9351

Query: 474  G 474
            G
Sbjct: 9352 G 9352



 Score =  115 bits (276), Expect = 9e-24
 Identities = 121/518 (23%), Positives = 203/518 (39%), Gaps = 27/518 (5%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
            D ++ + +P  L     G+P  ++ W K G+ V      +I        L      V  D
Sbjct: 8803 DYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVE-D 8861

Query: 80   AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVLECLPPRGSPEP 138
            AG Y C   N+ G     + +  + +L   + ++  E  + + GD+  L+C    G+PE 
Sbjct: 8862 AGQYNCYIENASG---KDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQC-QLAGTPEI 8917

Query: 139  NVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAG--TRESAIAT 195
             V W K    L      +MH  +    LV       D+G Y C A N+ G  +  + +  
Sbjct: 8918 GVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTV 8977

Query: 196  LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDD 254
             +  + P       DV    G  V F C + G     V W +      + P  +   LD+
Sbjct: 8978 QEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDN 9037

Query: 255  -GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLSPNSVNVESGNVA 310
              +L +     +  G+YSC A N +G+ S+S  L + +   PP  ++    V+   G  A
Sbjct: 9038 TATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGESA 9097

Query: 311  RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
             F C  TG     + W+ + +R I     S  KY  + + +    LT+   DK DS    
Sbjct: 9098 DFECHVTGTQPIKVSWAKD-SREI----RSGGKYQISYL-ENSAHLTVLKVDKGDS-GQY 9150

Query: 371  VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-I 429
             C AVN  G      +L +   +   PP  T   S      +  +      +   +PI +
Sbjct: 9151 TCYAVNEVGKDSCTAQLNIK--ERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITV 9208

Query: 430  AWYFEGEALIQNHRRNVT-NDGTLVL--KDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
            AWY     +       +T  + TLVL  +    +D+G YTC  S+  G  + + ++++  
Sbjct: 9209 AWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKE 9268

Query: 487  PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSW 524
            P  P +       V+   G   +   H      + + W
Sbjct: 9269 PKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQW 9306



 Score =  114 bits (275), Expect = 1e-23
 Identities = 126/486 (25%), Positives = 197/486 (40%), Gaps = 40/486 (8%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
            V    AP I  +   + VA    A   C    +P+   +W+K G  +      SI  +  
Sbjct: 4377 VVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKY 4436

Query: 66   LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA-VLREEFRLEPESKQSAQGDT 124
            +  L     +V  D G Y C+A+N YG+  S  ATL V       F   P+S  +  G  
Sbjct: 4437 ISSLEILRTQV-VDCGEYTCKASNEYGSV-SCTATLTVTEAYPPTFLSRPKSLTTFVGKA 4494

Query: 125  VVLECLPPRGSPEPNVYWKKNGQTL-------LFDGDSRMHLVDGGNLVIQDARQTDAGR 177
                C    G+P     W+K+G  L       + D +++ H+++  NL IQ     D G 
Sbjct: 4495 AKFIC-TVTGTPVIETIWQKDGAALSPSPNWKISDAENK-HILELSNLTIQ-----DRGV 4547

Query: 178  YQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
            Y C A N  G  +   A L I  KP+ I   E V +     V  +C+V  D    V W  
Sbjct: 4548 YSCKASNKFGA-DICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTW-- 4604

Query: 238  SAGGGNMPLGR-VKV-LDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
            S  G  +P G+  K+  +D   +L +    L D G Y C A N  G+ S S  +TV +PP
Sbjct: 4605 SKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPP 4664

Query: 294  S-INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
            S +     S  +  G  AR  C   G P   + W  + N+      +S          + 
Sbjct: 4665 SFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTW-FKNNKE-----LSESNTVRMYFVNS 4718

Query: 353  VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
              +L I D    DS  +  C AVN  GS     ++ +     + PP          +   
Sbjct: 4719 EAILDITDVKVEDS-GSYSCEAVNDVGSDSCSTEIVI-----KEPPSFIKTLEPADIVRG 4772

Query: 413  SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL---DKSDSGTYTCVA 469
            + A+  C    T    I+W+ + + +  + +  + +  +LV  ++   + +D G Y CV 
Sbjct: 4773 TNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVV 4832

Query: 470  SSRHGK 475
            ++  GK
Sbjct: 4833 ANEVGK 4838



 Score =  114 bits (274), Expect = 2e-23
 Identities = 125/493 (25%), Positives = 194/493 (39%), Gaps = 37/493 (7%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            E P     P  V   ++   +L C   G+P   + WYK    + S     I        +
Sbjct: 6442 EPPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSI 6501

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVVL 127
               +    SD G Y C+A N  G+    +  +    L+E   F  +  S     G+   L
Sbjct: 6502 HILNVDT-SDIGEYHCKAQNEVGS----DTCVCTVKLKEPPRFVSKLNSLTVVAGEPAEL 6556

Query: 128  ECLPPRGSPEPNVYWKKNGQTLLFDGDS-RMHLVDG-GNLVIQDARQTDAGRYQCIARNA 185
            +     G+    V W K  + ++ + ++ R+  V+    L    A   +AG+Y C  +N 
Sbjct: 6557 QA-SIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKND 6615

Query: 186  AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
             G  E+ +ATL +     ++     +    G + T +C+V G P   V W +    G + 
Sbjct: 6616 GGMEEN-MATLMVLEPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKD---GKLL 6671

Query: 246  LGRVK-----VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINL 297
                K          SLR+ +V   D G Y+ + +N+VG  S +  + V D   PPS   
Sbjct: 6672 TSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTR 6731

Query: 298  SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
               +     G      C   G    ++ W  E  + +     S  KY  T   D V  L 
Sbjct: 6732 RLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIV-----SGAKYQ-TTFSDNVCTLQ 6785

Query: 358  INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
            +N  D +D  N   C A N AGS   R  LTV      PP  +      + LP K++  F
Sbjct: 6786 LNSLDSSDMGN-YTCVAANVAGSDECRAVLTV----QEPPSFVKEPEPLEVLPGKNV-TF 6839

Query: 418  PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHG 474
                  TP   + W+     L++  R N+  + T   L L ++D S SG YTCV S+  G
Sbjct: 6840 TSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAG 6899

Query: 475  KYVWSGALLVDSP 487
            +   +  L V  P
Sbjct: 6900 QASCTTRLFVKEP 6912



 Score =  113 bits (272), Expect = 3e-23
 Identities = 120/456 (26%), Positives = 178/456 (39%), Gaps = 27/456 (5%)

Query: 43   IRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG-TARSRNATL 101
            + WY    LV SD     L     + L           G Y CEA N  G TA S   T+
Sbjct: 4318 VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTV 4377

Query: 102  HVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL-FDGDSRMHLV 160
             V       + + E  + A G      C   + +P     W K G+ +   D  S     
Sbjct: 4378 -VKRAAPVIKRKIEPLEVALGHLAKFTC-EIQSAPNVRFQWFKAGREIYESDKCSIRSSK 4435

Query: 161  DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH--IKPYLITGPEDVVAQTGSS 218
               +L I   +  D G Y C A N  G+  S  ATL +     P  ++ P+ +    G +
Sbjct: 4436 YISSLEILRTQVVDCGEYTCKASNEYGS-VSCTATLTVTEAYPPTFLSRPKSLTTFVGKA 4494

Query: 219  VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAE 275
              F C V G P+ + +W++  G    P    K+ D  +   L L N+ + D G YSC+A 
Sbjct: 4495 AKFICTVTGTPVIETIWQKD-GAALSPSPNWKISDAENKHILELSNLTIQDRGVYSCKAS 4553

Query: 276  NSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII 335
            N  GA      L + D P        V           C      + T+ WS +G +  +
Sbjct: 4554 NKFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQK--L 4611

Query: 336  FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395
             PG    K +     D +  L I      DS  T VC+A N AGSS     +TV      
Sbjct: 4612 PPG----KDYKICFEDKIATLEIPLAKLKDS-GTYVCTASNEAGSSSCSATVTVR----E 4662

Query: 396  PPPIITN-GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN---VTNDGT 451
            PP  +    PS   LP +S A   C    +P   + W+   + L +++      V ++  
Sbjct: 4663 PPSFVKKVDPSYLMLPGES-ARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAI 4721

Query: 452  LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
            L + D+   DSG+Y+C A +  G    S  +++  P
Sbjct: 4722 LDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEP 4757



 Score =  108 bits (259), Expect = 1e-21
 Identities = 121/490 (24%), Positives = 190/490 (38%), Gaps = 30/490 (6%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            E P  +++  D+     Q  TL     GS   ++ W KG  ++  D    +  + G+  L
Sbjct: 4849 EPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVL 4908

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL--EPESKQSAQGDTVVL 127
                 ++ S  G Y C A N  G+  S    +   +++E  ++    E  Q   GD   L
Sbjct: 4909 IIPDVQI-SFGGKYTCLAENEAGSQTS----VGELIVKEPAKIIERAELIQVTAGDPATL 4963

Query: 128  ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAA 186
            E     G+PE    W K+G+ L+     R+   +    L    A   D+G+Y     N  
Sbjct: 4964 E-YTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEV 5022

Query: 187  GTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
            G+   E+    L   I P+      +V +    +    C++ G     V W +  G    
Sbjct: 5023 GSSSCETTFTVLDRDIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKD-GKEIA 5081

Query: 245  PLGRVKVL---DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
               R ++       SL +  V + D G ++C A NSVG+  +SG L V +PPS    P S
Sbjct: 5082 ASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGS 5141

Query: 302  VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
             +V  G+      T  G    T+ W  +GN+ ++  G     Y      +    L +  T
Sbjct: 5142 KDVLPGSAVCLKSTFQGSTPLTIRW-FKGNKELVSGGSC---YITKEALESSLELYLVKT 5197

Query: 362  DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
              +DS  T  C   N AG       L V      P   +     +Q L         C  
Sbjct: 5198 --SDS-GTYTCKVSNVAGGVECSANLFV----KEPATFVEKLEPSQLLKKGDATQLACKV 5250

Query: 422  ICTPEPIIAWYFEGEALIQN--HRRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVW 478
              TP   I W+     + ++  HR + V +   L L D+   DSG Y C A +  G    
Sbjct: 5251 TGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHC 5310

Query: 479  SGALLV-DSP 487
            S  ++V +SP
Sbjct: 5311 SSIVIVKESP 5320



 Score =  107 bits (257), Expect = 2e-21
 Identities = 113/425 (26%), Positives = 183/425 (43%), Gaps = 37/425 (8%)

Query: 78   SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSP 136
            S++G Y C+  N  G    R  +  + VL     +E PE      G+   LEC+   G+P
Sbjct: 7544 SNSGKYICQIKNDAGM---RECSAVLTVLEPARIIEKPEPMTVTTGNPFALECVVT-GTP 7599

Query: 137  EPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195
            E +  W K+G+ L  D    +  ++   +L I  A  +D G Y    +N+ G       T
Sbjct: 7600 ELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSN---CT 7656

Query: 196  LKIHIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250
            + +H+      P  I   +DV A  G+SV  +CRV G     V W +    GN  +   K
Sbjct: 7657 VSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQD---GNEIVSGPK 7713

Query: 251  VLDDGS-----LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
                 S     L L  +  +D G Y+C A N  G+   S  LTV +PPS   +P+SV V 
Sbjct: 7714 CQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVL 7773

Query: 306  SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
             G    FT    G P   + W  +G+R ++ PG S +     ++ D VT L + +    +
Sbjct: 7774 PGMSLTFTSVIRGTPPFKVKW-FKGSRELV-PGESCN----ISLEDFVTELELFEVQPLE 7827

Query: 366  SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
            S     C   N AGS+     L V     + P       ++ ++   S  V   T   TP
Sbjct: 7828 S-GDYSCLVTNDAGSASCTTHLFV-----KEPATFVKRLADFSVETGSPIVLEATYTGTP 7881

Query: 426  EPIIAWYFEGEALIQNHRRNVT-NDGTLVLKDLDKS--DSGTYTCVASSRHGKYVWSGAL 482
               ++W  +   + Q+ R ++T  + + +L+ L+ +  D   Y+C+  +  G+ +    +
Sbjct: 7882 PISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALV 7941

Query: 483  LVDSP 487
             V  P
Sbjct: 7942 SVLEP 7946



 Score =  101 bits (243), Expect = 9e-20
 Identities = 121/511 (23%), Positives = 186/511 (36%), Gaps = 32/511 (6%)

Query: 31   LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
            L C+  GS   ++ W+     +VS        +  +  L+  +    SD G Y C A N 
Sbjct: 6746 LECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQL-NSLDSSDMGNYTCVAANV 6804

Query: 91   YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
             G+   R A L V      F  EPE  +   G  V    +  RG+P   V W +  + L+
Sbjct: 6805 AGSDECR-AVLTVQE-PPSFVKEPEPLEVLPGKNVTFTSVI-RGTPPFKVNWFRGARELV 6861

Query: 151  FDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
                  ++  D    L + +   + +G Y C+  N AG + S    L +      +    
Sbjct: 6862 KGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAG-QASCTTRLFVKEPAAFLKRLS 6920

Query: 210  DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR----VKVLDDGSLRLDNVILA 265
            D   + G S+  +    G     V W++   G N+        V       L + N    
Sbjct: 6921 DHSVEPGKSIILESTYTGTLPISVTWKKD--GFNITTSEKCNIVTTEKTCILEILNSTKR 6978

Query: 266  DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325
            D G+YSCE EN  G       ++  +PP        +    G+     C   G PE T+ 
Sbjct: 6979 DAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVS 7038

Query: 326  WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385
            W  +G+ T + P      Y      + V  L  N  + NDS     C A N  G++    
Sbjct: 7039 W-YKGD-TKLRPTPEYRTYFT----NNVATLVFNKVNINDS-GEYTCKAENSIGTA--SS 7089

Query: 386  KLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT---PEPI-IAWYFEGEALIQN 441
            K      + + PP      + Q   I+     P T  C      PI + WY +G  L  +
Sbjct: 7090 KTVFRIQERQLPPSF----ARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDD 7145

Query: 442  HRRN---VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAA 498
                   V N  TL +   D S SG Y+C AS+  G    S  L    P        +  
Sbjct: 7146 ENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIKPV 7205

Query: 499  DVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
             +  + G       H      + ++WS++NK
Sbjct: 7206 SIDVIAGESADFECHVTGAQPMRITWSKDNK 7236



 Score = 99.1 bits (236), Expect = 6e-19
 Identities = 125/504 (24%), Positives = 195/504 (38%), Gaps = 45/504 (8%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS--DTHRSILPAGGLFFL 69
            P    Q  DV      P   +C   GS   ++ WYK G  +    +   S L       +
Sbjct: 8984 PSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNI 9043

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEF---RLEPESKQSAQGDTVV 126
              T     S AG Y C ATN  G+A S    +        F   RL P    +  G++  
Sbjct: 9044 FKTD---RSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVD--AVVGESAD 9098

Query: 127  LECLPPRGSPEPNVYWKKNGQTLLFDGDSRM-HLVDGGNLVIQDARQTDAGRYQCIARNA 185
             EC    G+    V W K+ + +   G  ++ +L +  +L +    + D+G+Y C A N 
Sbjct: 9099 FEC-HVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNE 9157

Query: 186  AGTRESAIATLKIH---IKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGG 241
             G ++S  A L I    I P       + V +T G+S   + RV G     V W ++   
Sbjct: 9158 VG-KDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKN-NI 9215

Query: 242  GNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP---PSI 295
               P    ++    +   L++    + D G Y+C+  N  G+   +  + + +P   P  
Sbjct: 9216 EIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVF 9275

Query: 296  NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
            +     V V  G   + +C   G     + W   G    I P    D+  + +   G  V
Sbjct: 9276 DQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGRE--IKPS---DRC-SFSFASGTAV 9329

Query: 356  LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP----------IITNGPS 405
            L + D  K DS +  VC A N AGS   + K+T+       P              + P 
Sbjct: 9330 LELRDVAKADSGD-YVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQ 9388

Query: 406  NQTLPIKSMAVFPCTAICTPEPIIAWYF-EGEALIQNHRRNVTNDGT---LVLKDLDKSD 461
            +  +  K+ A F       P P + W   +   L Q  R  +   G    L ++D  K+D
Sbjct: 9389 SIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTD 9448

Query: 462  SGTYTCVASSRHGKYVWSGALLVD 485
            SG Y CVA + HG+   +  L VD
Sbjct: 9449 SGLYRCVAFNEHGEIESNVNLQVD 9472



 Score = 98.7 bits (235), Expect = 8e-19
 Identities = 121/527 (22%), Positives = 194/527 (36%), Gaps = 26/527 (4%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P  I +  DV         L CR  GS   ++ W++ G  +VS        +  +  L  
Sbjct: 7668 PSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNL 7727

Query: 72   THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
            +     SD G+Y C A N  G+    +A L V      F   P+S +   G ++    + 
Sbjct: 7728 SLLEP-SDTGIYTCVAANVAGSDEC-SAVLTVQE-PPSFEQTPDSVEVLPGMSLTFTSVI 7784

Query: 132  PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRE 190
             RG+P   V W K  + L+      + L D    L + + +  ++G Y C+  N AG   
Sbjct: 7785 -RGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAG--- 7840

Query: 191  SAIATLKIHIKP--YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
            SA  T  + +K     +    D   +TGS +  +    G P   V W +     +     
Sbjct: 7841 SASCTTHLFVKEPATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERC 7900

Query: 249  VKVLDDGSLRLDNV--ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
               + + S  L+ +   + D  +YSC  EN  G       ++V +PP        V    
Sbjct: 7901 SITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSVLEPPYFIEPLEHVEAVI 7960

Query: 307  GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
            G  A   C   G PE  + W  E  +    P       +     + V  L IN  D +D 
Sbjct: 7961 GEPATLQCKVDGTPEIRISWYKEHTKLRSAPA------YKMQFKNNVASLVINKVDHSDV 8014

Query: 367  RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
                 C A N  G+  V     +   + + PP       +    +     F C  I   E
Sbjct: 8015 -GEYSCKADNSVGA--VASSAVLVIKERKLPPFFARKLKDVHETLGFPVAFECR-INGSE 8070

Query: 427  PI-IAWYFEGEALIQNHRRN---VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482
            P+ ++WY +G  L  +       V N  TL +   D+S  G Y C AS+  G    S  L
Sbjct: 8071 PLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKL 8130

Query: 483  LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
            ++     P     +   V    G       H      + ++W+++N+
Sbjct: 8131 ILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNR 8177



 Score = 96.3 bits (229), Expect = 4e-18
 Identities = 107/488 (21%), Positives = 186/488 (38%), Gaps = 27/488 (5%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            E P  I++  + T      AT      GSP  +I W K   ++  D +  I     +  L
Sbjct: 5973 EPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVATL 6032

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS--AQGDTVVL 127
            +      +  +G Y C+A N  G  R     L    ++E  ++  ++K     + D + L
Sbjct: 6033 QI-RSVDNGHSGRYTCQAKNESGVERCYAFLL----VQEPAQIVEKAKSVDVTEKDPMTL 6087

Query: 128  ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAA 186
            EC+   G+PE  V W K+G+ ++      M   +   +  IQ   + D+G+Y     N  
Sbjct: 6088 ECVVA-GTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDF 6146

Query: 187  GTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
            G+   ++ +  L  +I P        +    GSS+  +C+V G       W +     + 
Sbjct: 6147 GSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEIST 6206

Query: 245  PLGRVKVLDDGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
                  V  + S+ L+  N+ L D   Y+C+  N  G  + SG LTV +PPS  + P   
Sbjct: 6207 SAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQ 6266

Query: 303  NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
                 +   F     G P   + W  +    +  P        +T+  +  +V    D  
Sbjct: 6267 QAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSV----DAS 6322

Query: 363  KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
            K        C   N  GS      L VT     PP  +    +++ +     +   C   
Sbjct: 6323 KT---GQYTCHVTNDVGSDSCTTMLLVT----EPPKFVKKLEASKIVKAGDSSRLECKIA 6375

Query: 423  CTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479
             +PE  + W+     L  + +  +T   +   + + +L   DSG + C A +  G    S
Sbjct: 6376 GSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCS 6435

Query: 480  GALLVDSP 487
              ++V  P
Sbjct: 6436 TKVIVKEP 6443



 Score = 95.1 bits (226), Expect = 1e-17
 Identities = 125/526 (23%), Positives = 204/526 (38%), Gaps = 32/526 (6%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFF 68
            E P  + +   +TV   +PA L     G+    ++W K    V+ ++    I     +  
Sbjct: 6535 EPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVAT 6594

Query: 69   LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDTVVL 127
            L+       ++AG Y C+  N  G   +  ATL   VL     +E     +   G+T  L
Sbjct: 6595 LQFAKAEP-ANAGKYICQIKNDGGMEENM-ATL--MVLEPAVIVEKAGPMTVTVGETCTL 6650

Query: 128  ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAA 186
            EC    G+PE +V W K+G+ L      +    +   +L I    + DAG Y    +N  
Sbjct: 6651 EC-KVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNV 6709

Query: 187  GTRESAIATLKIH---IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
            G + S  A + +    + P      ++     G+S   +C+V G     V W        
Sbjct: 6710 G-KSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIV 6768

Query: 244  MPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
                      D   +L+L+++  +D G Y+C A N  G+      LTV +PPS    P  
Sbjct: 6769 SGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPEP 6828

Query: 302  VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
            + V  G    FT    G P   + W   G R ++  G   + Y      D V  L + + 
Sbjct: 6829 LEVLPGKNVTFTSVIRGTPPFKVNW-FRGARELV-KGDRCNIYFE----DTVAELELFNI 6882

Query: 362  DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
            D + S     C   N AG +    +L V      P   +     +   P KS+ +   T 
Sbjct: 6883 DISQS-GEYTCVVSNNAGQASCTTRLFV----KEPAAFLKRLSDHSVEPGKSI-ILESTY 6936

Query: 422  ICTPEPIIAWYFEGEALIQNHRRN-VTNDGTLVLKDLD--KSDSGTYTCVASSRHGKYVW 478
              T    + W  +G  +  + + N VT + T +L+ L+  K D+G Y+C   +  G+ V 
Sbjct: 6937 TGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDV- 6995

Query: 479  SGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSW 524
             GAL+  S + P         + +  G              +T+SW
Sbjct: 6996 CGALV--STLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSW 7039



 Score = 94.7 bits (225), Expect = 1e-17
 Identities = 113/472 (23%), Positives = 178/472 (37%), Gaps = 24/472 (5%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            + P+ I++   V  A ++   L C+        + W K G  +       I     +  L
Sbjct: 4569 DKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATL 4628

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
                 ++  D+G Y C A+N  G++ S +AT+ V       +    S     G++  L C
Sbjct: 4629 EIPLAKL-KDSGTYVCTASNEAGSS-SCSATVTVREPPSFVKKVDPSYLMLPGESARLHC 4686

Query: 130  LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGT 188
               +GSP   V W KN + L      RM+ V+   ++ I D +  D+G Y C A N  G+
Sbjct: 4687 -KLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGS 4745

Query: 189  RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
             +S    + I   P  I   E      G++   QC V G    ++ W +          +
Sbjct: 4746 -DSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSK-K 4803

Query: 249  VKVLDDGSL---RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
             ++    SL    + +   AD GEY C   N VG         + +PP+     + +   
Sbjct: 4804 YRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKEPPTFVKKVDDLIAL 4863

Query: 306  SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
             G          G    ++ W ++G   I   G  +  +      +GV VL I D   + 
Sbjct: 4864 GGQTVTLQAAVRGSEPISVTW-MKGQEVIREDGKIKMSFS-----NGVAVLIIPDVQISF 4917

Query: 366  SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
                  C A N AGS    G+L V      P  II      Q +     A    T   TP
Sbjct: 4918 G-GKYTCLAENEAGSQTSVGELIV----KEPAKIIERAELIQ-VTAGDPATLEYTVAGTP 4971

Query: 426  EPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHG 474
            E    WY +G  L+ + +  ++   N   L     +  DSG YT   S+  G
Sbjct: 4972 ELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVG 5023



 Score = 94.3 bits (224), Expect = 2e-17
 Identities = 113/465 (24%), Positives = 176/465 (37%), Gaps = 26/465 (5%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            E P  + +P    V       L     GS    IRW+KG   +VS     I        L
Sbjct: 5131 EPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSL 5190

Query: 70   RATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
                 +  SD+G Y C+ +N  G    S N  +       E +LEP S+   +GD   L 
Sbjct: 5191 ELYLVKT-SDSGTYTCKVSNVAGGVECSANLFVKEPATFVE-KLEP-SQLLKKGDATQLA 5247

Query: 129  CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAG 187
            C    G+P   + W  N + +      RM  V+   ++ + D    D+G Y C A+N AG
Sbjct: 5248 C-KVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAG 5306

Query: 188  TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
            +   +   + +   PY     + +       V     V G P  ++ W +          
Sbjct: 5307 SDHCSSIVI-VKESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRK 5365

Query: 248  RVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
                + D   SL++   + AD GEY C   N VG+   S  +T+ +PPS      S +  
Sbjct: 5366 YKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIESTSSL 5425

Query: 306  SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD-KN 364
             G  A F  T  G    T+ W  + +       ++ D        + V  L ++  + K+
Sbjct: 5426 RGGTAAFQATLKGSLPITVTWLKDSDE------ITEDDNIRMTFENNVASLYLSGIEVKH 5479

Query: 365  DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
            D +   VC A N AG       L+V     + P  IT    +  +     A        T
Sbjct: 5480 DGK--YVCQAKNDAGIQRCSALLSV-----KEPATITEEAVSIDVTQGDPATLQVKFSGT 5532

Query: 425  PEPIIAWYFEGEALIQNHRRNVT-NDGTLVLK--DLDKSDSGTYT 466
             E    W+ +G+ L    +  ++  D   +LK    +K DSG YT
Sbjct: 5533 KEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYT 5577



 Score = 94.3 bits (224), Expect = 2e-17
 Identities = 116/490 (23%), Positives = 179/490 (36%), Gaps = 23/490 (4%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
            VT  E P  I++    +  R   A       GS    + W K    +  D +  +     
Sbjct: 5407 VTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENN 5466

Query: 66   LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
            +  L  +   V  D G Y C+A N  G  R  +A L V         E  S    QGD  
Sbjct: 5467 VASLYLSGIEVKHD-GKYVCQAKNDAGIQRC-SALLSVKE-PATITEEAVSIDVTQGDPA 5523

Query: 126  VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARN 184
             L+ +   G+ E    W K+GQ L      ++ + D  +++ I    + D+G Y    +N
Sbjct: 5524 TLQ-VKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQN 5582

Query: 185  AAGTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
              G    ++ I  L + I P      + + +  GS +  +C V G     + W +     
Sbjct: 5583 DVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEI 5642

Query: 243  NMPLGRVKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
            +          D +  L +  +   D G Y+C A N  G    SG+LTV +PP     P 
Sbjct: 5643 SASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQ 5702

Query: 301  SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
            S +V      +      G    T+ W  +     +  G +R  +      D  T L +  
Sbjct: 5703 SQDVNPNTRVQLKALVGGTAPMTIKWFKDNKE--LHSGAARSVWKD----DTSTSLELFA 5756

Query: 361  TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
                DS  T +C   N  G++  +  L V      PP  I        L       F C 
Sbjct: 5757 AKATDS-GTYICQLSNDVGTATSKATLFV----KEPPQFIKKPSPVLVLRNGQSTTFECQ 5811

Query: 421  AICTPEPIIAWYFEGEAL--IQNHRRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
               TP+  ++WY +G  +  IQ H  + +    T  +      +SGTY C A +  G   
Sbjct: 5812 ITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTAS 5871

Query: 478  WSGALLVDSP 487
             S  L V  P
Sbjct: 5872 CSIELKVKEP 5881



 Score = 80.6 bits (190), Expect = 2e-13
 Identities = 109/520 (20%), Positives = 209/520 (40%), Gaps = 44/520 (8%)

Query: 31   LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
            + C+  GS   + +W+K G  + +     ++       L   +  +   A  Y C+ +N 
Sbjct: 6183 MECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTAN-YTCKVSNV 6241

Query: 91   YGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
             G     +A   +  ++E   F ++P  +Q+    TV  + +  +G+P   + W K+   
Sbjct: 6242 AGD----DACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAIL-KGTPPFKIKWFKDDVE 6296

Query: 149  LLFDGDSRMHLVDGG----NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL 204
            L+  G      ++G     NL   DA +T  G+Y C   N  G+ +S    L +   P  
Sbjct: 6297 LV-SGPKCFIGLEGSTSFLNLYSVDASKT--GQYTCHVTNDVGS-DSCTTMLLVTEPPKF 6352

Query: 205  ITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---RVKVLDDGS-LRL 259
            +   E   + + G S   +C++ G P   V+W R+     +P     R+  +D  + +++
Sbjct: 6353 VKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEH--ELPASDKYRMTFIDSVAVIQM 6410

Query: 260  DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGR 319
            +N+   D G++ CEA+N  G+ S S  + V +PP  +  P  V           C  +G 
Sbjct: 6411 NNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLECELSGT 6470

Query: 320  PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379
            P   + W  +  +        + K  +      + +L ++ +D  +      C A N  G
Sbjct: 6471 PPFEVVWYKDKRQ---LRSSKKYKIASKNFHTSIHILNVDTSDIGEYH----CKAQNEVG 6523

Query: 380  SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI 439
            S        V +   + PP   +  ++ T+     A    +        + W  E E +I
Sbjct: 6524 SD-----TCVCTVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVI 6578

Query: 440  ---QNHRRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFF 495
               +N R   V N  TL     + +++G Y C   +  G       L+V   + P +   
Sbjct: 6579 RESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMEENMATLMV---LEPAVIVE 6635

Query: 496  RAADVSSLPGPPTKPITHNVTDT-SVTLSWSQNNKIGSSS 534
            +A  ++   G  T  +   V  T  +++ W ++ K+ +SS
Sbjct: 6636 KAGPMTVTVG-ETCTLECKVAGTPELSVEWYKDGKLLTSS 6674



 Score = 78.2 bits (184), Expect = 1e-12
 Identities = 111/491 (22%), Positives = 197/491 (40%), Gaps = 48/491 (9%)

Query: 134   GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
             G P P V W  N +TL  +       +   ++VI++ +++  G Y  +A+N AG R+  I
Sbjct: 17477 GKPPPTVTWNMNERTLPQEATIETTAISS-SMVIKNCQRSHQGVYSLLAKNEAGERKKTI 17535

Query: 194   ATLKIHIKPYLITGP---EDVVAQTGSSVTFQCRV-GGDPLPDVLWRRSAGGGNMPLGRV 249
                 + + P  +  P    ++  ++     F     GG P+ + +  +            
Sbjct: 17536 IVDVLDV-PGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVT 17594

Query: 250   KVLDDGSLRLDNVILADEGEYSCEAENSVGA---VSASGYLTVYDPPSINLSPNSVNVES 306
               +   +  +  +I      +   AENS+G    V  S  L + +P ++   P  + V+ 
Sbjct: 17595 YTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKE 17654

Query: 307   GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT-VLTINDTDKND 365
               V + T T T  P      S   N  +    +  +K+H     + ++   T+    + D
Sbjct: 17655 --VTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGD 17712

Query: 366   SRNTIVCSAVNYAGS---SFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
             +    V SAVN  G    SF    +T   D+  PP +  +     T+ +           
Sbjct: 17713 TYEYRV-SAVNIVGQGKPSFCTKPITC-KDELAPPTLHLDFRDKLTIRVGEAFALTGRYS 17770

Query: 423   CTPEPIIAWYFEGEALIQNHRRNV-TNDGTLVLKDLD--KSDSGTYTCVASSRHGKYVWS 479
               P+P ++W+ +   ++++ R ++ T   TL L+ +   +SDSG Y  V  +  G     
Sbjct: 17771 GKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSR--K 17828

Query: 480   GALLVDSPINPNIHFFRAADVSSLPGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSILGY 538
             G              F   +V   PGPP  P++ + VT   + +SW      G S I  Y
Sbjct: 17829 G--------------FCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNY 17874

Query: 539   QVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
              +E   +E   G +       W+ +     +T   V  L+ G  Y+F +  EN +G+S P
Sbjct: 17875 IIE--KKEV--GKDV------WMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDP 17924

Query: 599   SPVSDSVTVGD 609
               VSDS+   D
Sbjct: 17925 L-VSDSMKAKD 17934



 Score = 75.8 bits (178), Expect = 7e-12
 Identities = 162/702 (23%), Positives = 278/702 (39%), Gaps = 75/702 (10%)

Query: 130   LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGT 188
             +P +G P P + W K    L       +   D    +  ++  + DAG+Y     N+ G 
Sbjct: 20642 VPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGK 20701

Query: 189   RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV--GGDPLPD-VLWRRSAGGGNMP 245
             +E  I    +      +      +++  + VT++  +  GG P+ + V+ +R A   +  
Sbjct: 20702 KEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWS 20761

Query: 246   LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV-NV 304
                 +     S R+ N+       +   AEN  G +   G     D    + +P  V ++
Sbjct: 20762 TVTTEC-SKTSFRVANLEEGKSYFFRVFAENEYG-IGDPG--ETRDAVKASQTPGPVVDL 20817

Query: 305   ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP-GMSRDKYHATAVFDGVTVLTINDTDK 363
             +  +V++ +C+  G  +P    S  G+R I +      ++     V   ++ L  +  D 
Sbjct: 20818 KVRSVSKSSCSI-GWKKPH---SDGGSRIIGYVVDFLTEENKWQRVMKSLS-LQYSAKDL 20872

Query: 364   NDSRN-TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
              + +  T   SA N  G         V  DD   P +   G  +     K  + F     
Sbjct: 20873 TEGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIP 20932

Query: 423   CT--PEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGKYV 477
                 P P ++W    + L  + R +V +     TL++ D  KSD+G YT    +  G   
Sbjct: 20933 IKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTK- 20991

Query: 478   WSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSIL 536
               G + +               V   PG PT PI  + VT  ++TL W+     G S I 
Sbjct: 20992 -EGTISIK--------------VVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEIT 21036

Query: 537   GYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
              Y +E   R+++  NN       WV  A  V +T + V  L  G+ Y F V  EN +G+ 
Sbjct: 21037 NYILE--KRDSV--NNK------WVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGV- 21085

Query: 597   GPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEIL 656
             G    S+ +      +       V ++    N +   H  + +  T  D K  K     +
Sbjct: 21086 GEGLKSEPIVARHPFD-------VPDAPPPPNIVDVRH--DSVSLTWTDPK--KTGGSPI 21134

Query: 657   NFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEG 716
               Y+LE     F+  +++  +   KT +   D   F++T L +  +YEF ++       G
Sbjct: 21135 TGYHLE-----FKERNSLLWKRANKTPIRMRD---FKVTGLTEGLEYEFRVMAINLAGVG 21186

Query: 717   KPS-NSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLD 775
             KPS  S     LD  P  PP   E+  +   +V L W+ P+       +TGY  +V   D
Sbjct: 21187 KPSLPSEPVVALD--PIDPPGKPEVINITRNSVTLIWTEPKYD-GGHKLTGY--IVEKRD 21241

Query: 776   VPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817
             +P+   M A +  V +  +  +T+L  G  Y  +I A+   G
Sbjct: 21242 LPSKSWMKANHVNVPEC-AFTVTDLVEGGKYEFRIRAKNTAG 21282



 Score = 72.5 bits (170), Expect = 6e-11
 Identities = 67/228 (29%), Positives = 106/228 (46%), Gaps = 10/228 (4%)

Query: 6     VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
             +TSGEAP I ++  DVT    + A L+C+  G P P I+WY+ G  ++  + +  + + G
Sbjct: 31454 LTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELI-QSRKYKMSSDG 31512

Query: 66    LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV--LREEFRLEPESKQSAQGD 123
                          D GVY C ATN  G   + +  L  A       + L+ E    A G 
Sbjct: 31513 RTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLK-EKYYGAVGS 31571

Query: 124   TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM--HLVDGGNLVIQDA-RQTDAGRYQC 180
             T+ L  +   G P P + W  +GQ LL + ++    +     +LV+++  R+T AG+Y+ 
Sbjct: 31572 TLRLHVM-YIGRPVPAMTW-FHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKV 31629

Query: 181   IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228
                N  GT + AI  ++I  KP   TGP  + A   +S     +   D
Sbjct: 31630 QLSNVFGTVD-AILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPAD 31676



 Score = 72.1 bits (169), Expect = 8e-11
 Identities = 114/458 (24%), Positives = 180/458 (39%), Gaps = 67/458 (14%)

Query: 177   RYQCIARNAAGTRESAIATLKIHIK-PY---LITGPEDVVAQTGSSVTFQ-----CRVGG 227
             +++ IA+N  G  E++ A+  +  K P+      G  ++++ +  SVT Q     C  G 
Sbjct: 31328 QFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGK 31387

Query: 228   DPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG-------A 280
             + L   +  R +G         + + D    +  ++ A E E+   AEN  G       A
Sbjct: 31388 EILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTA 31447

Query: 281   VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340
             +S    LT  + P I      V  + G  A+ +C   GRP P + W   G   I     S
Sbjct: 31448 MSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELI----QS 31503

Query: 341   RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP--P 398
             R KY  ++  DG T      T++ +      C A N  G      KL + +     P  P
Sbjct: 31504 R-KYKMSS--DGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYP 31560

Query: 399   IITN--GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT----- 451
             +     G    TL +  M       I  P P + W F G+ L+QN   N+T + T     
Sbjct: 31561 LKEKYYGAVGSTLRLHVM------YIGRPVPAMTW-FHGQKLLQN-SENITIENTEHYTH 31612

Query: 452   LVLKDLD-KSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKP 510
             LV+K++  K+ +G Y    S+  G         VD+ ++         ++   P  PT P
Sbjct: 31613 LVMKNVQRKTHAGKYKVQLSNVFG--------TVDAILD--------VEIQDKPDKPTGP 31656

Query: 511   IT-HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQ 569
             I    +   S  +SW      G S I  Y VE    E   G         W +++  +  
Sbjct: 31657 IVIEALLKNSAVISWKPPADDGGSWITNYVVE--KCEAKEGAE-------WQLVSSAISV 31707

Query: 570   THYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
             T   + +L     Y F V  +N+ G+S P  VS  V +
Sbjct: 31708 TTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVII 31745



 Score = 68.9 bits (161), Expect = 8e-10
 Identities = 47/180 (26%), Positives = 90/180 (50%), Gaps = 11/180 (6%)

Query: 110  FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVI 167
            F L+P S +  +G T   + L   G P P  +W  +GQ ++ D   ++ + + G  +L+I
Sbjct: 1459 FVLKPVSFKCLEGQTARFD-LKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLII 1517

Query: 168  QDARQTDAGRYQCIARNAAGTRE-SAIATLKI---HIKPYLITGPEDVVAQTGSSVTFQC 223
              A  +D+G +  +A+N AG    S I T++     +KP  +   ++V  + GS +  + 
Sbjct: 1518 VPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSQLEMKV 1577

Query: 224  RVGGDPLPDVLWRRSAG---GGNMPLGRVK-VLDDGSLRLDNVILADEGEYSCEAENSVG 279
            R  G+P PD++W +++        P  R++    + +L++D+ +  D   Y+  A N  G
Sbjct: 1578 RATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAG 1637



 Score = 68.1 bits (159), Expect = 1e-09
 Identities = 102/414 (24%), Positives = 171/414 (41%), Gaps = 38/414 (9%)

Query: 92   GTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLF 151
            G A S  ATL+V     EFR   +  +  +    + EC      P+  V W K+ Q L  
Sbjct: 3043 GKATS-TATLYVEARHIEFRKHIKDIKVLEKKRAMFEC--EVSEPDITVQWMKDDQELQI 3099

Query: 152  DGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED 210
                ++      + L+I   R +DAG+Y  +A     T +  +    + I+   I     
Sbjct: 3100 TDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRS--IKKEVQ 3157

Query: 211  VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLR---LDNVILAD 266
            V+ +  + V F+  V  D + D  W +     N  +  R K + +  +    +     +D
Sbjct: 3158 VIEKQRAVVEFE--VNEDDV-DAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSD 3214

Query: 267  EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326
             GEY+  A  +  +V+   Y+   +PP +      V V+SG  ARF    +GRP+P + W
Sbjct: 3215 AGEYTFVAGRNRSSVTL--YVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISW 3272

Query: 327  SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
              E    ++  G      H    +   T+L I    ++ +  T  C A N  G +     
Sbjct: 3273 YKE--EQLLSTGFKCKFLHDGQEY---TLLLIEAFPEDAAVYT--CEAKNDYGVATTSAS 3325

Query: 387  LT-----VTSDDDR----PPPIITNGPSNQTLPIKSM-AVFPCTAICTPEPIIAWYFEGE 436
            L+     V S D      PP IIT  P   T+  +   A F C    T +  ++WY + +
Sbjct: 3326 LSVEVPEVVSPDQEMPVYPPAIIT--PLQDTVTSEGQPARFQCRVSGT-DLKVSWYSKDK 3382

Query: 437  ALIQNHRRNVTN-DGT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
             +  +    +T  + T  L + +    D GTYT VAS+  G+   +  L +++P
Sbjct: 3383 KIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAP 3436



 Score = 68.1 bits (159), Expect = 1e-09
 Identities = 83/320 (25%), Positives = 128/320 (40%), Gaps = 37/320 (11%)

Query: 292   PPSINLSPNSVN---VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
             PPS+ L    +    V++G   RF     G P PT  W+ +G+       +  D+++   
Sbjct: 18434 PPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSE------IKTDEHYTVE 18487

Query: 349   VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN-- 406
               +  +VLTI +  + D+    + +  N AGS  V   LTV    D P P    GP N  
Sbjct: 18488 TDNFSSVLTIKNCLRRDTGEYQI-TVSNAAGSKTVAVHLTVL---DVPGP--PTGPINIL 18541

Query: 407   QTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYT 466
                P      +         P+I +  E +   ++    V++  +     +     G   
Sbjct: 18542 DVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGC-E 18600

Query: 467   CVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQ 526
              V   R    +  G  L  +P      F       S P PP KP+  ++T+ + T+SW+ 
Sbjct: 18601 YVFRVRAENKIGVGPPLDSTPTVAKHKF-------SPPSPPGKPVVTDITENAATVSWTL 18653

Query: 527   NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMF 585
                 G S I GY +E   R  ++G         WV + +  +    + V  L  G TY F
Sbjct: 18654 PKSDGGSPITGYYME---RREVTGK--------WVRVNKTPIADLKFRVTGLYEGNTYEF 18702

Query: 586   IVRTENSHGLSGPSPVSDSV 605
              V  EN  GLS PSP SD +
Sbjct: 18703 RVFAENLAGLSKPSPSSDPI 18722



 Score = 68.1 bits (159), Expect = 1e-09
 Identities = 156/706 (22%), Positives = 269/706 (38%), Gaps = 83/706 (11%)

Query: 130   LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
             +P +G P P V W K+   L    +   +      L+I +  + D G++     N AG +
Sbjct: 21725 VPIKGRPAPEVTWTKDNINLKNRANIE-NTESFTLLIIPECNRYDTGKFVMTIENPAGKK 21783

Query: 190   ESAIATLKIHIK-PYLITGPEDVVAQTGSSVTFQCRV----GGDPLPD-VLWRRSAGGGN 243
                +    +    P L   P D+   T  SVT    +    GG  + + ++ +R A   +
Sbjct: 21784 SGFVNVRVLDTPGPVLNLRPTDI---TKDSVTLHWDLPLIDGGSRITNYIVEKREATRKS 21840

Query: 244   MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
                   K     + ++  +    E  +   AEN  G    +              P+S+N
Sbjct: 21841 YSTATTKC-HKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLN 21899

Query: 304   VESGNVARFTCT-ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
             +   ++ + T + A  +P+      + G   I       D++       G+  +  N T+
Sbjct: 21900 IM--DITKSTVSLAWPKPKHDGGSKITGY-VIEAQRKGSDQWTHITTVKGLECVVRNLTE 21956

Query: 363   KNDSRNTIVCSAVNYAGSSFVR-GKLTVTSDDDRPPPIITNGPSNQTLPIKS--MAVFPC 419
               +   T    AVN AG S  R  +  +  +    P +   G   + +  K+        
Sbjct: 21957 GEEY--TFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEI 22014

Query: 420   TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLD---KSDSGTYTCVASSRHGKY 476
               +  P+P + W    + L Q  R N     T  + +++   +SDSG Y   A +  G+ 
Sbjct: 22015 PVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGE- 22073

Query: 477   VWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSI 535
                    V   I   +H         +PGPPT PI  + V+   VT SW      G   I
Sbjct: 22074 -------VGDVITIQVH--------DIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPI 22118

Query: 536   LGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGL 595
               Y VE+  R+T        +S  WV +A  V +T Y    L  G+ Y F V+ +N +G+
Sbjct: 22119 SNYVVEM--RQT--------DSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGV 22168

Query: 596   SGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEI 655
              GP   S  +     +N  ++  G   + +             + A   DS TI     +
Sbjct: 22169 -GPGITSACIV----ANYPFKVPGPPGTPQ-------------VTAVTKDSMTISWHEPL 22210

Query: 656   LN-FYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKF 714
              +    + G  +  +  + I  +   K ++  N    F+ + L     YEF +I      
Sbjct: 22211 SDGGSPILGYHVERKERNGILWQTVSKALVPGNI---FKSSGLTDGIAYEFRVIAENMAG 22267

Query: 715   EGKPSN-SRVAQTLDDV-PDGPPINIEMFILNTTTVHLKWSPPELQLQNGI-ITGYNVVV 771
             + KPS  S     LD + P G P+ +    +   TV LKW+ PE     G  IT Y  +V
Sbjct: 22268 KSKPSKPSEPMLALDPIDPPGKPVPLN---ITRHTVTLKWAKPE--YTGGFKITSY--IV 22320

Query: 772   NWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817
                D+P  + + A  + + +     ++ LT   +Y  ++ A+   G
Sbjct: 22321 EKRDLPNGRWLKANFSNILE-NEFTVSGLTEDAAYEFRVIAKNAAG 22365



 Score = 66.9 bits (156), Expect = 3e-09
 Identities = 77/272 (28%), Positives = 113/272 (41%), Gaps = 32/272 (11%)

Query: 45   WYKGGVLV---VSDTHRSILPAG-GLFFLRATHGRVHSDAGVY-WCEATNSYGTARSRNA 99
            WYK G+ +   V + H+ ++       F+  T     SDAG Y +    N        NA
Sbjct: 3179 WYKDGIEINFQVQERHKYVVERRIHRMFISETR---QSDAGEYTFVAGRNRSSVTLYVNA 3235

Query: 100  TLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL 159
                 VL+E   L+P + QS +       C    G P+P + W K  Q LL  G     L
Sbjct: 3236 PEPPQVLQE---LQPVTVQSGKPARF---CAVISGRPQPKISWYKEEQ-LLSTGFKCKFL 3288

Query: 160  VDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK-------------PYL 204
             DG    L++ +A   DA  Y C A+N  G   ++ A+L + +              P +
Sbjct: 3289 HDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTS-ASLSVEVPEVVSPDQEMPVYPPAI 3347

Query: 205  ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG-SLRLDNVI 263
            IT  +D V   G    FQCRV G  L    + +          R+   +D   L +    
Sbjct: 3348 ITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAY 3407

Query: 264  LADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295
              DEG Y+  A N+VG VS++  L++  P SI
Sbjct: 3408 PEDEGTYTFVASNAVGQVSSTANLSLEAPESI 3439



 Score = 66.5 bits (155), Expect = 4e-09
 Identities = 83/325 (25%), Positives = 135/325 (41%), Gaps = 39/325 (12%)

Query: 497   AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556
             A D    P PP  P  ++ T +SV+LSW +    G S I+GY VEV   +    +N  R 
Sbjct: 20509 ARDPQYPPAPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEV---KRADSDNWVRC 20565

Query: 557   SRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWE 616
             +     + + + +T + V  L+    Y F V   N  G S PS V D     D    L  
Sbjct: 20566 N-----LPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKD---ILIP 20617

Query: 617   GTGVSNSTEYRNNILTDHIVELIEATPIDSK-TIKLMWEILNFYYLEGLFIYFRPLDNIT 675
               G  ++ + R  ++    V +    P+  +   K+ W               +P  N+ 
Sbjct: 20618 PEGELDA-DLRKTLILRAGVTMRLYVPVKGRPPPKITWS--------------KP--NVN 20660

Query: 676   IEYEMKTILHSNDVSGF-EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGP 734
             +   +   + S D   F    ++ KY   ++ L    +   GK   + V + LD    GP
Sbjct: 20661 LRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILT--LENSCGKKEYTIVVKVLD--TPGP 20716

Query: 735   PINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATS 794
             P+N+ +  ++  + ++ W PP +   + II   N VV   D  A +   +  TT    TS
Sbjct: 20717 PVNVTVKEISKDSAYVTWEPPIIDGGSPII---NYVVQKRD--AERKSWSTVTTECSKTS 20771

Query: 795   LIMTNLTSGVSYSVQIAAETIIGLG 819
               + NL  G SY  ++ AE   G+G
Sbjct: 20772 FRVANLEEGKSYFFRVFAENEYGIG 20796



 Score = 64.1 bits (149), Expect = 2e-08
 Identities = 80/315 (25%), Positives = 132/315 (41%), Gaps = 36/315 (11%)

Query: 504   PGPPTKPIT-HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
             PGPPT P+   ++T+ SVTL W      G S +  Y +    RET        ++  W  
Sbjct: 27497 PGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYIL--LKRET--------STAVWTE 27546

Query: 563   IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSN 622
             ++  V +T   V  L  G  Y F ++ EN  G+S     S  VTV      L   T    
Sbjct: 27547 VSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHID-SACVTV-----KLPYTTPGPP 27600

Query: 623   STEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKT 682
             ST +  N+ T   + +    P+ +    ++      Y+LE      +  ++I  +   K 
Sbjct: 27601 STPWVTNV-TRESITVGWHEPVSNGGSAVVG-----YHLE-----MKDRNSILWQKANKL 27649

Query: 683   ILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFI 742
             ++ +   + F++T++     YEF +        GKPS+        D  + PP N+ +  
Sbjct: 27650 VIRT---THFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACE-PPRNVRITD 27705

Query: 743   LNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTS 802
             ++  +V L W  P        ITGY  +V   D+P  +   A  T V + T  I++ LT 
Sbjct: 27706 ISKNSVSLSWQQPAFD-GGSKITGY--IVERRDLPDGRWTKASFTNVTE-TQFIISGLTQ 27761

Query: 803   GVSYSVQIAAETIIG 817
                Y  ++ A   +G
Sbjct: 27762 NSQYEFRVFARNAVG 27776



 Score = 64.1 bits (149), Expect = 2e-08
 Identities = 41/123 (33%), Positives = 60/123 (48%), Gaps = 8/123 (6%)

Query: 487   PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRE 546
             P +    F++AAD    PGPP K    + T +S+TL WS+    G S++ GY VE+  R+
Sbjct: 28077 PFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEI--RQ 28134

Query: 547   TLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVT 606
                   T  +++G       V  T YVV +L PG+ Y F V   N  G   P  +++ V 
Sbjct: 28135 GEEEEWTTVSTKG------EVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQ 28188

Query: 607   VGD 609
               D
Sbjct: 28189 AKD 28191



 Score = 63.7 bits (148), Expect = 3e-08
 Identities = 167/814 (20%), Positives = 292/814 (35%), Gaps = 92/814 (11%)

Query: 20    DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
             D  V   Q    NC      + A +W++    +   +   IL    ++ LR     +   
Sbjct: 13575 DTRVKEQQEVVFNCEVNTEGAKA-KWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQ 13633

Query: 80    AGVYWCEATNSYGTARSRNATLHVAVLREEFRL-EP-ESKQSAQGDTVVLECLPPRGSPE 137
             A  Y    TN  G   +  +  ++ V  E+ R+ EP +  ++ +  +V   C   R +  
Sbjct: 13634 AN-YNVSLTNHRG--ENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNV- 13689

Query: 138   PNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIAT 195
               + W KNG+ + FD +   + VD     L I+D    D G Y       AG  +S    
Sbjct: 13690 -TLKWTKNGEEVPFD-NRVSYRVDKYKHMLTIKDCGFPDEGEYIV----TAGQDKSVAEL 13743

Query: 196   LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR-VKVLDD 254
             L I      +   ED          F C++  +   +V W R+  G  +  G+  K   D
Sbjct: 13744 LIIEAPTEFVEHLEDQTVTEFDDAVFSCQLSREKA-NVKWYRN--GREIKEGKKYKFEKD 13800

Query: 255   GSLRLDNVILAD-EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313
             GS+    +I+ D   +  CE    V    +   L V + P   + P    +E+       
Sbjct: 13801 GSIH--RLIIKDCRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVF 13858

Query: 314   CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
                  + +  + W    N  ++  G  + +  +      + +  I   D+ + R      
Sbjct: 13859 LAELNKDKVEVQWL--RNNMVVVQG-DKHQMMSEGKIHRLQICDIKPRDQGEYRFI---- 13911

Query: 374   AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF 433
                 A     R KL + +      P I     +  + +             P+    W+ 
Sbjct: 13912 ----AKDKEARAKLELAA-----APKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFK 13962

Query: 434   EGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIH 493
             E E L            +  + +  K D G Y  V  ++HGK         +  IN    
Sbjct: 13963 ENEPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGK--------AEGFIN---- 14010

Query: 494   FFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNT 553
               +  DV   PGP          D  V+L+W +    G S I+GY VE   R  +     
Sbjct: 14011 -LKVIDV---PGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVE---RRDIK---- 14059

Query: 554   PRNSRGWVVIARRVHQTHYVVKSLIPG-ITYMFIVRTENSHGLSGPSPVSDSVTVGDDSN 612
                 + WV+   R     + V  L  G + Y+F V   N  G   P    + V    ++ 
Sbjct: 14060 ---RKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPV----EAR 14112

Query: 613   SLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPL- 671
             S ++  G        N  +TD          ++   + L WE   +     +  Y   L 
Sbjct: 14113 SKYDVPGPP-----LNVTITD----------VNRFGVSLTWEPPEYDGGAEITNYVIELR 14157

Query: 672   DNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSR-VAQTLDDV 730
             D  +I ++    + + D+S   +T + +  +Y F +    +   GKPS +    +  D +
Sbjct: 14158 DKTSIRWDTAMTVRAEDLSA-TVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPI 14216

Query: 731   P-DGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTV 789
                 PP+N+       ++V LKW PP L+     I GY  ++   +     + +  N  +
Sbjct: 14217 ERPSPPVNLTSSDQTQSSVQLKWEPP-LKDGGSPILGY--IIERCE-EGKDNWIRCNMKL 14272

Query: 790   HQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQ 823
                 +  +T L  G  Y  +++AE   G+   S+
Sbjct: 14273 VPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSE 14306



 Score = 63.3 bits (147), Expect = 4e-08
 Identities = 61/205 (29%), Positives = 85/205 (41%), Gaps = 14/205 (6%)

Query: 5    YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
            YV + E P ++++   VTV   +PA       G P P I WYK   L+ +      L  G
Sbjct: 3232 YVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDG 3291

Query: 65   GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR-----EEFRLEPESKQS 119
              + L         DA VY CEA N YG A + +A+L V V       +E  + P +  +
Sbjct: 3292 QEYTLLLIEA-FPEDAAVYTCEAKNDYGVA-TTSASLSVEVPEVVSPDQEMPVYPPAIIT 3349

Query: 120  AQGDTVVLECLPPR-----GSPEPNVYWKKNGQTLLFDGDSRM-HLVDGGNLVIQDARQT 173
               DTV  E  P R        +  V W    + +      RM    D   L I +A   
Sbjct: 3350 PLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPE 3409

Query: 174  DAGRYQCIARNAAGTRESAIATLKI 198
            D G Y  +A NA G + S+ A L +
Sbjct: 3410 DEGTYTFVASNAVG-QVSSTANLSL 3433



 Score = 63.3 bits (147), Expect = 4e-08
 Identities = 95/355 (26%), Positives = 144/355 (40%), Gaps = 45/355 (12%)

Query: 269   EYSCEAENSVGAVSASGYLTV-------YDPPSINLSP---NSVNVESGN-VARFTCTAT 317
             E+   A+N+ GA+SA    T        Y+ P+I L P   + + +++G+ +     +  
Sbjct: 21272 EFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISIL 21331

Query: 318   GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
             G+P P   WS  G    I P    D    T+     ++LTI    + D+    + +A N 
Sbjct: 21332 GKPLPKSSWSKAGKD--IRPS---DITQITSTPTS-SMLTIKYATRKDAGEYTI-TATNP 21384

Query: 378   AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437
              G+     K+TV  D   PP     GP    + I +++    T   TP P+       ++
Sbjct: 21385 FGTKVEHVKVTVL-DVPGPP-----GP----VEISNVSAEKATLTWTP-PLEDGGSPIKS 21433

Query: 438   LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHF--F 495
              I   R       T+V +D+    S  +      +  +Y++  + +        +     
Sbjct: 21434 YILEKRETSRLLWTVVSEDIQ---SCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPV 21490

Query: 496   RAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPR 555
             +  D    PGPP KP   NVT  + T+SW +    G S I GY VE   RE        +
Sbjct: 21491 KMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVE--RRE--------K 21540

Query: 556   NSRGWV-VIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
              S  WV  I   V      V  L  G TY F V  EN  G+  PS  SDSV + D
Sbjct: 21541 KSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD 21595



 Score = 62.9 bits (146), Expect = 5e-08
 Identities = 112/466 (24%), Positives = 179/466 (38%), Gaps = 49/466 (10%)

Query: 17    QPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75
             +PL D+ V   + A   C      +  ++W+K G  +       I+  G +  L   +  
Sbjct: 13305 RPLTDLQVREKEMARFECELSRE-NAKVKWFKDGAEIKKGKKYDIISKGAVRIL-VINKC 13362

Query: 76    VHSDAGVYWCEATNSYGTARSRNATLHVAVLREE--FRLEPESKQSAQGDTVVLECLPPR 133
             +  D   Y CE      TAR+      + VL EE  F     + + ++ DT+ L C   +
Sbjct: 13363 LLDDEAEYSCEVR----TARTSGM---LTVLEEEAVFTKNLANIEVSETDTIKLVCEVSK 13415

Query: 134   GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRES 191
               P   V W K  + ++  G   + L +G    LVIQ+A   DAG Y C  R  +   + 
Sbjct: 13416 --PGAEVIWYKGDEEIIETGRYEI-LTEGRKRILVIQNAHLEDAGNYNC--RLPSSRTDG 13470

Query: 192   AIATLKIH-IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RV 249
              +   K+H +    I+ P+++    G    F C +  +  P V W+R      +  G + 
Sbjct: 13471 KV---KVHELAAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRD--DKTLESGDKY 13524

Query: 250   KVLDDGSLR---LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
              V+ DG  R   + +  L D G Y       VGA  A+ +LTV +   I +      V+ 
Sbjct: 13525 DVIADGKKRVLVVKDATLQDMGTYVV----MVGAARAAAHLTVIEKLRIVVPLKDTRVKE 13580

Query: 307   GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
                  F C          ++    N   IF      KY      D V  L I D   +D 
Sbjct: 13581 QQEVVFNCEVNTEGAKAKWFR---NEEAIF---DSSKY-IILQKDLVYTLRIRDAHLDDQ 13633

Query: 367   RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
              N  V S  N+ G +       +  ++D    I+      +T+  KS+  F C  +    
Sbjct: 13634 ANYNV-SLTNHRGENVKSAANLIVEEEDL--RIVEPLKDIETMEKKSV-TFWC-KVNRLN 13688

Query: 427   PIIAWYFEGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTCVA 469
               + W   GE +  ++R +   D     L +KD    D G Y   A
Sbjct: 13689 VTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTA 13734



 Score = 61.3 bits (142), Expect = 2e-07
 Identities = 94/380 (24%), Positives = 141/380 (37%), Gaps = 43/380 (11%)

Query: 30   TLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
            T +C+  G P P I WYK G  +   + ++      G   LR     +  D G+Y   A+
Sbjct: 1309 TFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVV-LPEDEGIYTAFAS 1367

Query: 89   NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
            N  G           A+   +  +EP +   A      LE +    S  P    +   ++
Sbjct: 1368 NIKGN----------AICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSP----RSVSRS 1413

Query: 149  LLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208
             +    +RM         +  AR +   R +        T ES +  L    KP  +  P
Sbjct: 1414 PIRMSPARMSPARMSPARMSPARMSPGRRLE-------ETDESQLERL---YKPVFVLKP 1463

Query: 209  EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDG--SLRLDNVILA 265
                   G +  F  +V G P+P+  W        N    +V + +DG  SL +     +
Sbjct: 1464 VSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPS 1523

Query: 266  DEGEYSCEAENSVGAVSASGYLTV-----YDPPSINLSPNSVNVESGNVARFTCTATGRP 320
            D GE++  A+N  G  S S  LTV        P       +VN++ G+       ATG P
Sbjct: 1524 DSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSQLEMKVRATGNP 1583

Query: 321  EPTMFWSVEGNRTIIFPGMSRDKYHATAV--FDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
             P + W    N  II P     KY    +    G   L I+ T   DS      +A+N A
Sbjct: 1584 NPDIVWL--KNSDIIVP----HKYPKIRIEGTKGEAALKIDSTVSQDSA-WYTATAINKA 1636

Query: 379  GSSFVRGKLTVTSDDDRPPP 398
            G    R K+ V  +   P P
Sbjct: 1637 GRDTTRCKVNVEVEFAEPEP 1656



 Score = 61.3 bits (142), Expect = 2e-07
 Identities = 104/467 (22%), Positives = 180/467 (38%), Gaps = 50/467 (10%)

Query: 12    PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
             PY   +  D T        L C    + +P ++W+K G   +  +  +++ A G   +  
Sbjct: 12945 PYFTGKLQDYTGVEKDEVILQCEISKADAP-VKWFKDGK-EIKPSKNAVIKADGKKRMLI 13002

Query: 72    THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
                 + SD G Y C+      + +       + ++R    +E    ++A+ +T + E   
Sbjct: 13003 LKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEISE--- 13059

Query: 132   PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGTR 189
                  + +  WK  G+ LL   D  +   +G   +LV+ + R    G    +   AA  +
Sbjct: 13060 ----DDIHANWKLKGEALLQTPDCEIK-EEGKIHSLVLHNCRLDQTGG---VDFQAANVK 13111

Query: 190   ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249
              SA   +K  +   L+   +DV    G + TF C +  + +P V W    G    P  +V
Sbjct: 13112 SSAHLRVKPRVIG-LLRPLKDVTVTAGETATFDCELSYEDIP-VEWYLK-GKKLEPSDKV 13168

Query: 250   KVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP-NSVNVE 305
                 +G   +L L +V L D GE    A++          L V +PP     P     VE
Sbjct: 13169 VPRSEGKVHTLTLRDVKLEDAGEVQLTAKD----FKTHANLFVKEPPVEFTKPLEDQTVE 13224

Query: 306   SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG-VTVLTINDTDKN 364
              G  A   C  + R    + W   G        +   KY   A  DG V  L I+D    
Sbjct: 13225 EGATAVLECEVS-RENAKVKWFKNGTEI-----LKSKKYEIVA--DGRVRKLVIHDCTPE 13276

Query: 365   DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP-SNQTLPIKSMAVFPCTAIC 423
             D + T  C A ++  S      L V      PP +    P ++  +  K MA F C  + 
Sbjct: 13277 DIK-TYTCDAKDFKTSC----NLNVV-----PPHVEFLRPLTDLQVREKEMARFEC-ELS 13325

Query: 424   TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDK---SDSGTYTC 467
                  + W+ +G  + +  + ++ + G + +  ++K    D   Y+C
Sbjct: 13326 RENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSC 13372



 Score = 61.3 bits (142), Expect = 2e-07
 Identities = 78/315 (24%), Positives = 118/315 (37%), Gaps = 38/315 (12%)

Query: 301   SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
             ++NV   + A   C  TG P+P + W  +G + II  G+   KY       G   L I  
Sbjct: 31863 NLNVRYQSNATLVCKVTGHPKPIVKWYRQG-KEIIADGL---KYRIQEFKGGYHQLIIAS 31918

Query: 361   TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
                +D+       A N  GS      L V        P    G          +      
Sbjct: 31919 VTDDDA-TVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIP 31977

Query: 421   AICTPEPIIAWYFEGEALIQNHRRN---VTNDGTLVL--KDLDKSDSGTYTCVASSRHGK 475
                 P+P+I W  +G+ LI N+      VT   T ++    +++ D+G Y   A +R G 
Sbjct: 31978 FSGKPDPVITWQ-KGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFG- 32035

Query: 476   YVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSI 535
                     +D             DV+ +P PP      +V+  SV L+W++    G S I
Sbjct: 32036 --------IDQKTVE-------LDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKI 32080

Query: 536   LGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGL 595
               Y VE               +  W+ +  +  +T Y V +L    +Y F V  EN  GL
Sbjct: 32081 TNYIVE----------KCATTAERWLRVG-QARETRYTVINLFGKTSYQFRVIAENKFGL 32129

Query: 596   SGPSPVSDSVTVGDD 610
             S PS  S+     +D
Sbjct: 32130 SKPSEPSEPTITKED 32144



 Score = 60.9 bits (141), Expect = 2e-07
 Identities = 54/191 (28%), Positives = 84/191 (43%), Gaps = 9/191 (4%)

Query: 10    EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFF 68
             +AP+  E+  ++ V     ATL C+  G P P ++WY+ G  +++D  +  I    G + 
Sbjct: 31853 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 31912

Query: 69    LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEPESKQSAQGDTV 125
                       DA VY   ATN  G+  S  A+L V V   +     LE      A    V
Sbjct: 31913 QLIIASVTDDDATVYQVRATNQGGSV-SGTASLEVEVPAKIHLPKTLEGMGAVHALRGEV 31971

Query: 126   VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQD-ARQTDAGRYQCIA 182
             V   +P  G P+P + W+K GQ L+ +      +V     +LV  +   + DAG Y   A
Sbjct: 31972 VSIKIPFSGKPDPVITWQK-GQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCA 32030

Query: 183   RNAAGTRESAI 193
             +N  G  +  +
Sbjct: 32031 KNRFGIDQKTV 32041



 Score = 60.1 bits (139), Expect = 4e-07
 Identities = 97/403 (24%), Positives = 157/403 (38%), Gaps = 58/403 (14%)

Query: 425   PEPIIAWYFEGEALIQNHRR----NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
             P P + W  +G+ L +   R    +     TLV+KD  ++D G Y    S+  G      
Sbjct: 25662 PIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTK---- 25717

Query: 481   ALLVDSPINPNIHFFRAADVSSLPGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQ 539
                   PI           V   PGPP  P+    VT     L+W+   + G ++I  Y 
Sbjct: 25718 ----SIPIT--------VKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYI 25765

Query: 540   VEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
             +E   RET        +   W  ++  V   +Y V  L+PG  Y+F V   N +G+  P 
Sbjct: 25766 IE--KRET--------SRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPL 25815

Query: 600   PVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFY 659
               S  VT  +     ++  G  ++ E   + +T   + +  A P+D    +         
Sbjct: 25816 E-SGPVTACNP----YKPPGPPSTPEV--SAITKDSMVVTWARPVDDGGTE--------- 25859

Query: 660   YLEGLFIYFRPLDNIT-IEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKP 718
              +EG  +  R  + +   +   KT+    D+    +T L +   YEF +        G+P
Sbjct: 25860 -IEGYILEKRDKEGVRWTKCNKKTL---TDLR-LRVTGLTEGHSYEFRVAAENAAGVGEP 25914

Query: 719   SNSRVAQTLDDV--PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDV 776
             S   V     D   P GPP N ++   + ++V L WS P +      + GY  VV   + 
Sbjct: 25915 SEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKP-IYDGGAPVKGY--VVEVKEA 25971

Query: 777   PANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819
              A++       T  Q     +T L     Y+ +I A    G+G
Sbjct: 25972 AADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVG 26014



 Score = 60.1 bits (139), Expect = 4e-07
 Identities = 106/451 (23%), Positives = 182/451 (40%), Gaps = 61/451 (13%)

Query: 177   RYQCIARNAAG-TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQ----CRVGGDPLP 231
             +++  A N+AG +  S  +   + + P    G  D +  T  ++T +     R GG  + 
Sbjct: 28755 QFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIV 28814

Query: 232   DVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVS----ASGYL 287
                  +  G           + +    +  +   D  E+   A N+VG +S    +SG +
Sbjct: 28815 GYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGII 28874

Query: 288   TVYD---PPSINLSP---NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341
                D   PP +   P   + + ++SG   R      GRP P + W  +G          R
Sbjct: 28875 MTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEI-----EKR 28929

Query: 342   DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401
                  T V  G T L + D  + D R      A N +GS+    K+ V    D P  ++ 
Sbjct: 28930 MNMEITDVL-GSTSLFVRDATR-DHRGVYTVEAKNASGSAKAEIKVKV---QDTPGKVV- 28983

Query: 402   NGPSNQT-LPIKSMAVF---PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL 457
              GP   T +  + M ++   P    C P   I  Y     +I+  +R  +     +++D 
Sbjct: 28984 -GPIRFTNITGEKMTLWWDAPLNDGCAP---ITHY-----IIE--KRETSRLAWALIED- 29031

Query: 458   DKSDSGTYTCVASSRHGKYVWSGALL----VDSPINPNIHFFRAADVSSLPGPPTKPITH 513
              K ++ +YT +      +Y +  + +    V  P++ +     A    ++P  P  P   
Sbjct: 29032 -KCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVV--AQIQYTVPDAPGIPEPS 29088

Query: 514   NVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV-VIARR-VHQTH 571
             N+T  S+TL+W++    G S I  Y +E   RE        + S  WV VI++R + +T 
Sbjct: 29089 NITGNSITLTWARPESDGGSEIQQYILE--RRE--------KKSTRWVKVISKRPISETR 29138

Query: 572   YVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602
             + V  L  G  Y F V  EN+ G+   S +S
Sbjct: 29139 FKVTGLTEGNEYEFHVMAENAAGVGPASGIS 29169



 Score = 60.1 bits (139), Expect = 4e-07
 Identities = 82/312 (26%), Positives = 130/312 (41%), Gaps = 39/312 (12%)

Query: 304   VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
             V  G V R T    G+P P   W+ EG        +S+    AT+  +  T L I + D+
Sbjct: 31075 VRQGGVIRLTIPIKGKPFPICKWTKEGQ------DISKRAMIATS--ETHTELVIKEADR 31126

Query: 364   NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN-QTLPIKSMAV-FPCTA 421
              DS  T      N  G   V  K+ V    + P      GP     + ++S+ V +   A
Sbjct: 31127 GDS-GTYDLVLENKCGKKAVYIKVRVIGSPNSP-----EGPLEYDDIQVRSVRVSWRPPA 31180

Query: 422   ICTPEPIIAWYFEGEALIQNHRRNVTND--GT-LVLKDLDKSDSGTYTCVASSRHGKYVW 478
                   I+ +  E   + +     + +   GT LV+K L ++    +   A ++ G    
Sbjct: 31181 DDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGI--- 31237

Query: 479   SGALLVDSPINPNIHFFRAADVSSLPGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILG 537
             S  L  + P+ P           + P PP+ P    +VT +SV+LSWS+    G S + G
Sbjct: 31238 SKPLKSEEPVTPKTPL-------NPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTG 31290

Query: 538   YQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSG 597
             Y +E   R+  S +   R+++       ++  T Y V  L+P   Y F +  +N  GLS 
Sbjct: 31291 YYIE---RKETSTDKWVRHNK------TQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSE 31341

Query: 598   PSPVSDSVTVGD 609
              SP S+ V   D
Sbjct: 31342 TSPASEPVVCKD 31353



 Score = 59.7 bits (138), Expect = 5e-07
 Identities = 93/402 (23%), Positives = 162/402 (40%), Gaps = 57/402 (14%)

Query: 425   PEPIIAWYFEGEALIQNHR---RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
             P P I WY + + L  N      N T+  ++++KD D+ +SG Y     +  G    S  
Sbjct: 27827 PAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSA--SAT 27884

Query: 482   LLVDSPINPNIHFFRAADVSSLPGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSILGYQV 540
             + V               +   PGPP  PI    VT   +TL W      G + I  Y V
Sbjct: 27885 IRVQ--------------ILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIV 27930

Query: 541   EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600
             E   RET        +   W +++  + +       +I G  Y+F VR  N +G+  P  
Sbjct: 27931 E--KRET--------SRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLE 27980

Query: 601   VSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYY 660
              SDSV V  ++       G+   T+   N +T     ++ + PI      +     + Y+
Sbjct: 27981 -SDSV-VAKNAFVTPGPPGIPEVTKITKNSMT-----VVWSRPIADGGSDI-----SGYF 28028

Query: 661   LEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN 720
             LE         D  ++ +  K +  +   +  ++T L + + Y++ +       +G  S 
Sbjct: 28029 LE-------KRDKKSLGW-FKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSE 28080

Query: 721   -SRVAQTLDDV-PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPA 778
              S   +  D + P GPP  I +     +++ L WS P        +TGY V +   +   
Sbjct: 28081 PSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYD-GGSAVTGYVVEIRQGE--- 28136

Query: 779   NKSMVAINTTVH-QATSLIMTNLTSGVSYSVQIAAETIIGLG 819
              +    ++T    + T  +++NL  GV+Y  +++A    G G
Sbjct: 28137 EEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQG 28178



 Score = 59.7 bits (138), Expect = 5e-07
 Identities = 60/224 (26%), Positives = 94/224 (41%), Gaps = 22/224 (9%)

Query: 83    YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW 142
             Y+C  T      + R  T+ +     EF L   +K +  G+ V    +     PEP+V W
Sbjct: 32594 YYCRRTMK--KIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFG-VTITVHPEPHVTW 32650

Query: 143   KKNGQTLL-FDGDSRMHLV-DGG--NLVIQDARQTDAGRYQCIARNAAGTRE-SAIATLK 197
              K+GQ +   D D +     D G   L I      D   Y  +ARN  G     A  T+ 
Sbjct: 32651 YKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVT 32710

Query: 198   IH-------IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RV 249
             +H       ++P       +   Q G SV F+ RV G P P + W +   G  + LG  +
Sbjct: 32711 LHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKD--GQPLSLGPNI 32768

Query: 250   KVLDDG----SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
             +++ +G    +L + + +  D G Y   A N+ G+ S   +L V
Sbjct: 32769 EIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 32812



 Score = 59.3 bits (137), Expect = 6e-07
 Identities = 100/398 (25%), Positives = 156/398 (39%), Gaps = 57/398 (14%)

Query: 425   PEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
             P P I+W  +GE L Q  R NV    T   L +K+ +K D G YT  A++  G    + +
Sbjct: 25266 PRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLS 25325

Query: 482   LLVDSPINPNIHFFRAADVSSLPGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSILGYQV 540
             ++V                   PGPP  P+  + V+   V +SW      G   I  Y V
Sbjct: 25326 VIV----------------LEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIV 25369

Query: 541   EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600
             E   R+T +          W +++  V +T   +  L  G  Y F +  EN +G S  +P
Sbjct: 25370 E--KRDTTTTT--------WHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKS--AP 25417

Query: 601   VSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDH-IVELIEATPIDSKTIKLMWEILNFY 659
             +     +       ++  G    T +  +I  D  +V+  E  P++    K++      Y
Sbjct: 25418 LDSKAVIVQYP---FKEPGPPG-TPFVTSISKDQMLVQWHE--PVNDGGTKIIG-----Y 25466

Query: 660   YLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPS 719
             +LE      +  ++I      KT +       F+ T L +  +YEF +        GKPS
Sbjct: 25467 HLEQ-----KEKNSILWVKLNKTPIQDTK---FKTTGLDEGLEYEFKVSAENIVGIGKPS 25518

Query: 720   NSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPAN 779
                      D P  PP   E  ++    V LKW  P        ITGY  +V   D+P  
Sbjct: 25519 KVSECFVARD-PCDPPGRPEAIVITRNNVTLKWKKPAYD-GGSKITGY--IVEKKDLPDG 25574

Query: 780   KSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817
             + M A  T V + T   ++ L     Y  ++ A    G
Sbjct: 25575 RWMKASFTNVLE-TEFTVSGLVEDQRYEFRVIARNAAG 25611



 Score = 58.8 bits (136), Expect = 8e-07
 Identities = 77/355 (21%), Positives = 140/355 (39%), Gaps = 30/355 (8%)

Query: 139   NVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAI-AT 195
             +V W  NG  L    + R + V G +  L I+ A   D G   CI++   G  +     T
Sbjct: 33994 DVKWVLNGVELTNSEEYR-YGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLT 34052

Query: 196   LKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGGGNMPLGRV 249
             L   +   P  I+ P       G +V F C + G+P P++ W ++    +   N+ + R 
Sbjct: 34053 LSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRS 34112

Query: 250   KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDPPS--INLSPNSVNV 304
             +  +  SL + N  ++D G+Y+ +A+N  G  SA+  L V    + PS  + L  +    
Sbjct: 34113 R--NVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTS 34170

Query: 305   ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
               G+ +  +   +   +   F S   +       M+  K+ A+     ++ +  +  + +
Sbjct: 34171 LQGSFSSQSVQMSASKQEASFSSFSSSSA---SSMTEMKF-ASMSAQSMSSMQESFVEMS 34226

Query: 365   DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
              S    + +      S+    K  +       PP I   PS+ ++    +    C     
Sbjct: 34227 SSSFMGISNMTQLESSTSKMLKAGIRG----IPPKIEALPSDISIDEGKVLTVACAFTGE 34282

Query: 425   PEPIIAWYFEGEALIQN-----HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
             P P + W   G  +        H  N  +  TL++ D+ K D G YT    +  G
Sbjct: 34283 PTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 34337



 Score = 58.4 bits (135), Expect = 1e-06
 Identities = 91/356 (25%), Positives = 132/356 (37%), Gaps = 47/356 (13%)

Query: 6    VTSGEAPYIIE---QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL- 61
            +T G+ P   +    P+D  V   + A   C   G+    + W K    + S     I  
Sbjct: 9073 LTEGKNPPFFDIRLAPVDAVVG--ESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISY 9130

Query: 62   --PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLE-PES 116
               +  L  L+   G    D+G Y C A N  G   S  A L++   ++   F     E+
Sbjct: 9131 LENSAHLTVLKVDKG----DSGQYTCYAVNEVGKD-SCTAQLNIKERLIPPSFTKRLSET 9185

Query: 117  KQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ--DARQTD 174
             +  +G++  LE     GS    V W KN   +    +  +   +   LV+Q   A   D
Sbjct: 9186 VEETEGNSFKLEGRVA-GSQPITVAWYKNNIEIQPTSNCEITFKNN-TLVLQVRKAGMND 9243

Query: 175  AGRYQCIARNAAGTRESAIATLKIHIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDP 229
            AG Y C   N AG   SA+ T  I IK     P        V    G  V   C V G  
Sbjct: 9244 AGLYTCKVSNDAG---SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSE 9300

Query: 230  LPDVLWRRSAGGGNMPLGRVKV-LDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGY 286
               + W + AG    P  R       G+  L L +V  AD G+Y C+A N  G+ +    
Sbjct: 9301 PIRIQWLK-AGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSK 9359

Query: 287  LTVYDPPSIN---------------LSPNSVNVESGNVARFTCTATGRPEPTMFWS 327
            +T+ D P++                  P S+ V     A F     G P P + W+
Sbjct: 9360 VTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWT 9415



 Score = 58.4 bits (135), Expect = 1e-06
 Identities = 109/456 (23%), Positives = 174/456 (38%), Gaps = 59/456 (12%)

Query: 370   IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS--MAVFPCTAICTPEP 427
             I  +AVN +  S     +T+ +++  PP I  +      L +K+        T    P P
Sbjct: 20194 IARTAVNISPPSEPSDPVTILAENV-PPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMP 20252

Query: 428   IIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
              ++W  +G  L       +    N  TL L  +++ DSG YT  A +  G    S  + +
Sbjct: 20253 TVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSK--SATIKL 20310

Query: 485   DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFS 544
                            V   PGPP     + +      LSW    + G S I  Y V+   
Sbjct: 20311 K--------------VLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVD--K 20354

Query: 545   RETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDS 604
             RET   N        W  ++  V  T   V+ LI G  Y F +  EN +G+  P     +
Sbjct: 20355 RETSRPN--------WAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPA 20406

Query: 605   VTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGL 664
             +     + + ++  G  +     +NI  DH+  +    P D     +   +L     + +
Sbjct: 20407 I-----AKNPYDPPGRCDPPVI-SNITKDHMT-VSWKPPADDGGSPITGYLLEKRETQAV 20459

Query: 665   FIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN-SRV 723
                     N T +   K I+        + T L++ T+YEF +    K   GKPS+ S+ 
Sbjct: 20460 --------NWT-KVNRKPIIERT----LKATGLQEGTEYEFRVTAINKAGPGKPSDASKA 20506

Query: 724   AQTLD-DVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSM 782
             A   D   P  PP   +++    ++V L W  P     + II GY V V   D   + + 
Sbjct: 20507 AYARDPQYPPAPPAFPKVYDTTRSSVSLSWGKPAYDGGSPII-GYLVEVKRAD---SDNW 20562

Query: 783   VAINTTVH-QATSLIMTNLTSGVSYSVQIAAETIIG 817
             V  N   + Q T   +T L     Y  ++ A   IG
Sbjct: 20563 VRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIG 20598



 Score = 58.4 bits (135), Expect = 1e-06
 Identities = 72/290 (24%), Positives = 113/290 (38%), Gaps = 21/290 (7%)

Query: 10    EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
             +AP  I QP    +   Q     C   G PSP I W+K  + +   ++ SI  +  ++ L
Sbjct: 34059 DAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSL 34118

Query: 70    RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
                +  V SD+G Y  +A N  G   S  A+L V  L EE   E   + S  GDT +   
Sbjct: 34119 EIRNASV-SDSGKYTIKAKNFRGQC-SATASLMVLPLVEEPSREVVLRTS--GDTSLQGS 34174

Query: 130   LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG-- 187
                +         + +  +      S M  +   ++  Q          +  + +  G  
Sbjct: 34175 FSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGIS 34234

Query: 188   ----TRESAIATLKIHIK---PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
                    S    LK  I+   P +   P D+    G  +T  C   G+P P+V W  S G
Sbjct: 34235 NMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTW--SCG 34292

Query: 241   G---GNMPLGR--VKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSAS 284
             G    +   GR  ++  DD  +L + +V   D G Y+    N  G+ SA+
Sbjct: 34293 GRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSAT 34342



 Score = 58.0 bits (134), Expect = 1e-06
 Identities = 79/324 (24%), Positives = 134/324 (41%), Gaps = 35/324 (10%)

Query: 500   VSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRG 559
             VS +P  P K    +VT ++VTL+W +    G S + GY +E     T          R 
Sbjct: 30558 VSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGT---------ERW 30608

Query: 560   WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTG 619
               V+  +     + V SL  G  Y+F +R +N  G+S P     +VTV D    +     
Sbjct: 30609 MKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQD--LRVLPTID 30666

Query: 620   VSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYE 679
             +S   +   ++     VEL+   PI  +           ++  G  +  R  + +T+E  
Sbjct: 30667 LSTMPQKTIHVPAGRPVELV--IPIAGRPPPAA-----SWFFAGSKL--RESERVTVETH 30717

Query: 680   MKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIE 739
              K    +        T++R   +Y   L    K   G  S + +   + D P  P   I+
Sbjct: 30718 TKVAKLT-----IRETTIRDTGEYTLEL----KNVTGTTSET-IKVIILDKPGPPTGPIK 30767

Query: 740   MFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTN 799
             +  ++ T++ + W PPEL      ++GY  VV   D       + ++ +V ++T    T 
Sbjct: 30768 IDEIDATSITISWEPPELD-GGAPLSGY--VVEQRDA-HRPGWLPVSESVTRST-FKFTR 30822

Query: 800   LTSGVSYSVQIAAETIIGLGPFSQ 823
             LT G  Y  ++AA    G+G + Q
Sbjct: 30823 LTEGNEYVFRVAATNRFGIGSYLQ 30846



 Score = 57.6 bits (133), Expect = 2e-06
 Identities = 89/364 (24%), Positives = 144/364 (39%), Gaps = 37/364 (10%)

Query: 259   LDNVILADEGEYSCEAENSVGAVSASGYLTVYD------PPSINLSPNSVNVESGNVARF 312
             +++++   E E+  +A N+ G    S  +   D      PPSI+L    + VE G     
Sbjct: 17005 VEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLK-EFMEVEEGTNVNI 17063

Query: 313   TCTATGRPEPTMFW-SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371
                  G P PT+ W      +      +  D +    V D    L I  + ++D+     
Sbjct: 17064 VAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDT-GLYT 17122

Query: 372   CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431
              +AVN  G++    +L V     RP P +  GP    +  +S++    T    P      
Sbjct: 17123 ITAVNNLGTASKEMRLNVLG---RPGPPV--GP----IKFESVSADQMTLSWFPPKD--- 17170

Query: 432   YFEGEALIQNH--RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVW----SGALLVD 485
               +G + I N+   +   N  T V    +  +  TYT        +YV+         + 
Sbjct: 17171 --DGGSKITNYVIEKREANRKTWVHVSSEPKEC-TYTIPKLLEGHEYVFRIMAQNKYGIG 17227

Query: 486   SPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSR 545
              P++       A ++ S+PG P KP   +VT  S+T++W +    G S + GY +E+  +
Sbjct: 17228 EPLDSEPE--TARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEM--K 17283

Query: 546   ETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605
             +T S     R +R    I        Y V  LI G  Y F V   N+ G+   S  SD  
Sbjct: 17284 DTTS-KRWKRVNRD--PIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPA 17340

Query: 606   TVGD 609
             T  D
Sbjct: 17341 TARD 17344



 Score = 57.6 bits (133), Expect = 2e-06
 Identities = 36/101 (35%), Positives = 47/101 (46%), Gaps = 11/101 (10%)

Query: 503   LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGW-V 561
             +PGPP KP+ +NVT   ++L+W      G S + G+ VE             RNS  W  
Sbjct: 28683 IPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVE----------KKERNSILWQK 28732

Query: 562   VIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602
             V    +    Y    L+ G+ Y F V  ENS GLS PS  S
Sbjct: 28733 VNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPS 28773



 Score = 57.2 bits (132), Expect = 3e-06
 Identities = 90/342 (26%), Positives = 138/342 (40%), Gaps = 51/342 (14%)

Query: 273   EAENSVGAVSASGYLTVYDPPSINLSP---NSVNVESGNVARFTCTATGRPEPTMFWSVE 329
             E   S GA++A   +   DPP I++ P   +++ V +G   +      G+P PT+ W ++
Sbjct: 23451 EPSESTGAITARDEV---DPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQW-IK 23506

Query: 330   GNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389
             G++ +     +R +  +T   D  T L++ D  + DS N I+  A N AG   V   + V
Sbjct: 23507 GDQEL--SNTARLEIKST---DFATSLSVKDAVRVDSGNYIL-KAKNVAGERSVTVNVKV 23560

Query: 390   TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP------EPIIAWYFEGEALIQNHR 443
                 DRP      GP    + I  +    CT    P        II +  E     +   
Sbjct: 23561 L---DRP------GPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVW 23611

Query: 444   RNV-TNDGTLVLK--DLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADV 500
               V  N  TL  K   L + +  T+  +A +++G     G  L   P+     F      
Sbjct: 23612 TVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGV----GEPLESEPVVAKNPFV----- 23662

Query: 501   SSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGW 560
               +P  P  P    VT  S+ + W +    G S ILGY +E   +E +      +     
Sbjct: 23663 --VPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHK----- 23715

Query: 561   VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602
                 R + +    V  LI    Y F V  EN+ GLS PSP S
Sbjct: 23716 ----RLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPS 23753



 Score = 57.2 bits (132), Expect = 3e-06
 Identities = 75/320 (23%), Positives = 126/320 (39%), Gaps = 33/320 (10%)

Query: 293   PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
             P +  + +S +V+ G   +     +GRP+PT+ W+ +G      P     + + T   D 
Sbjct: 24157 PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDG-----LPLKQTTRINVTDSLD- 24210

Query: 353   VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP--PIITNGPSNQTLP 410
             +T L+I +T K+D     +  A N  G      ++ VT D   PP  P+  +  S +++ 
Sbjct: 24211 LTTLSIKETHKDDGGQYGITVA-NVVGQKTASIEI-VTLDKPDPPKGPVKFDDVSAESIT 24268

Query: 411   IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470
             +        T  C     I    +    + +         TL +  L       +   A 
Sbjct: 24269 LSWNPPL-YTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAE 24327

Query: 471   SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530
             +R+G+   S AL  D PI     +         PGPP  P    ++  S+ + W +    
Sbjct: 24328 NRYGQ---SFALESD-PIVAQYPYKE-------PGPPGTPFATAISKDSMVIQWHEPVNN 24376

Query: 531   GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMFIVRT 589
             G S ++GY +E             RNS  W  + +  +H T +  ++L  GI Y F V  
Sbjct: 24377 GGSPVIGYHLE----------RKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYA 24426

Query: 590   ENSHGLSGPSPVSDSVTVGD 609
             EN  G+   S  S+     D
Sbjct: 24427 ENIVGVGKASKNSECYVARD 24446



 Score = 57.2 bits (132), Expect = 3e-06
 Identities = 73/327 (22%), Positives = 124/327 (37%), Gaps = 23/327 (7%)

Query: 12    PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
             P I+    D TV+    A    +A G P P   W K G  +       +    G FFL  
Sbjct: 33779 PVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLE- 33837

Query: 72    THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR----EEFRLEPESKQSAQGDTVVL 127
              H    SD+G+Y C   NS G+  S +  L +  ++    ++   +  S+ + Q   VV 
Sbjct: 33838 IHKTDTSDSGLYTCTVKNSAGSV-SSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQ 33896

Query: 128   ECLPPRG--SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
             E +  +   S E  +   K+ + L    ++   L+       ++ +++ A   +    + 
Sbjct: 33897 EEISQKALRSEEIKMSEAKSQEKLALKEEASKVLIS------EEVKKSAATSLEKSIVHE 33950

Query: 186   AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW-RRSAGGGNM 244
               T+ S  A+ ++     +      +    G  +  +  + G    DV W        N 
Sbjct: 33951 EITKTSQ-ASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG--ATDVKWVLNGVELTNS 34007

Query: 245   PLGRVKVL-DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT----VYDPPSINLSP 299
                R  V   D +L +      DEG  +C ++   G V     LT    + D P+    P
Sbjct: 34008 EEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQP 34067

Query: 300   NSVNVESGNVARFTCTATGRPEPTMFW 326
              S N+  G    FTC  +G P P + W
Sbjct: 34068 RSQNINEGQNVLFTCEISGEPSPEIEW 34094



 Score = 56.8 bits (131), Expect = 3e-06
 Identities = 94/378 (24%), Positives = 138/378 (36%), Gaps = 24/378 (6%)

Query: 178   YQCIARNAAG-----TRESAIATLKIHIK-PYLITGPE--DV-VAQTGSSVTFQCRVGGD 228
             ++ IARNAAG     +  S   T +  I  P     P+  DV V   G +   +  + G 
Sbjct: 25602 FRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGK 25661

Query: 229   PLPDVLWRRSAGGGNMPLGRVKV---LDDGSLRLDNVILADEGEYSCEAENSVGAVSASG 285
             P+PDV+W +          R+++   +   +L + + I  D G+Y  +  N  G  S   
Sbjct: 25662 PIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPI 25721

Query: 286   YLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345
              + V D P     P  V      V    C     P P        +  II       +  
Sbjct: 25722 TVKVLDRPGPPEGPLKVT----GVTAEKCYLAWNP-PLQDGGANISHYII-EKRETSRLS 25775

Query: 346   ATAVFDGVTVLTINDTDKNDSRNTIV-CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404
              T V   V  L    T        I    AVN  G         VT+ +   PP   + P
Sbjct: 25776 WTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTP 25835

Query: 405   SNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGT 464
                 +   SM V     +      I  Y   +   +  R    N  TL   DL    +G 
Sbjct: 25836 EVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT--DLRLRVTGL 25893

Query: 465   YTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSW 524
                   S   +     A  V  P  P++ F+RA D    PGPP+ P   + + +SV+L+W
Sbjct: 25894 TE--GHSYEFRVAAENAAGVGEPSEPSV-FYRACDALYPPGPPSNPKVTDTSRSSVSLAW 25950

Query: 525   SQNNKIGSSSILGYQVEV 542
             S+    G + + GY VEV
Sbjct: 25951 SKPIYDGGAPVKGYVVEV 25968



 Score = 56.4 bits (130), Expect = 4e-06
 Identities = 87/353 (24%), Positives = 141/353 (39%), Gaps = 41/353 (11%)

Query: 269   EYSCEAENSVGAVS----ASGYLTVYD---PPSINLSP---NSVNVESGNVARFTCTATG 318
             E+   A N+  +VS    ++G + V D   PP + +     + + V++G V +      G
Sbjct: 26683 EFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAG 26742

Query: 319   RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
             RP P + W+ +G   I     +R +  +T   D  T+LT+ D  + D+    V +  N A
Sbjct: 26743 RPLPVISWAKDG---IEIEERARTEIIST---DNHTLLTVKDCIRRDT-GQYVLTLKNVA 26795

Query: 379   GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438
             G+  V     V    D+P      GP    L I  +    C+ +    P      + +  
Sbjct: 26796 GTRSVAVNCKVL---DKP------GPPAGPLEINGLTAEKCS-LSWGRPQEDGGADIDYY 26845

Query: 439   IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH-GKYVWSGALLVDSPINPNIHFFRA 497
             I   R       T+   +L  +       +  + +  +        V  P+       +A
Sbjct: 26846 IVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVA--IKA 26903

Query: 498   ADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNS 557
              D  ++P PPT     +VT  S+TL WS+    G S I GY +E   RE        +NS
Sbjct: 26904 LDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIE--RRE--------KNS 26953

Query: 558   RGWVVIARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
               WV + ++ V+        L  G  Y + V  EN+ GLS PS  S  +   D
Sbjct: 26954 LRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAED 27006



 Score = 56.0 bits (129), Expect = 6e-06
 Identities = 120/556 (21%), Positives = 206/556 (37%), Gaps = 70/556 (12%)

Query: 417   FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRH 473
             FP      P P   W  +G  +  +    V  D     L +K+  + D+G Y    S+  
Sbjct: 18457 FPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAA 18516

Query: 474   GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITH-NVTDTSVTLSWSQNNKIGS 532
             G    +            +H      V  +PGPPT PI   +VT   +T+SW      G 
Sbjct: 18517 GSKTVA------------VHL----TVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGG 18560

Query: 533   SSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENS 592
             S ++ Y VE          +T +++  W V++    +T   +  L  G  Y+F VR EN 
Sbjct: 18561 SPVINYIVEK--------QDTRKDT--WGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENK 18610

Query: 593   HGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLM 652
              G+ GP P+  + TV     S     G    T+   N  T                  + 
Sbjct: 18611 IGV-GP-PLDSTPTVAKHKFSPPSPPGKPVVTDITENAAT------------------VS 18650

Query: 653   WEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEF--FLIPF 710
             W +        +  Y+     +T ++         D+  F +T L +   YEF  F    
Sbjct: 18651 WTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLK-FRVTGLYEGNTYEFRVFAENL 18709

Query: 711   YKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVV 770
                 +  PS+  +       P GPPIN ++   +  T  L W+ P L      I GY VV
Sbjct: 18710 AGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKP-LSDGGSPILGY-VV 18767

Query: 771   VNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNID 830
                    A  + +  +  + Q  +  +  L  G  Y  +I A  I+G G   +     + 
Sbjct: 18768 ECQKPGTAQWNRINKDELIRQC-AFRVPGLIEGNEYRFRIKAANIVGEGEPRE-----LA 18821

Query: 831   SRSVGLDLLSRYPMNGEVSIVAGDFVMETWFYFLIGAIVLFKIIVIAGIIYVRKYNIFAK 890
                +  D+L  +P   E+ +   D V+       I  +   K      I + ++  +  +
Sbjct: 18822 ESVIAKDIL--HPPEVELDVTCRD-VITVRVGQTIRILARVKGRPEPDITWTKEGKVLVR 18878

Query: 891   KSALPNIYDSNGTSLVTQMNIKAAVSLSHP--LTSCYNKNTVTKTESLLWMENQPGVCLS 948
             +  +  I D        ++ IK AV   H   + S  N +   +  +++ + ++PG C +
Sbjct: 18879 EKRVDLIQDLPR----VELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQN 18934

Query: 949   GNQTSQSKEKTNFEYD 964
                T+ +KE     ++
Sbjct: 18935 LKVTNVTKENCTISWE 18950



 Score = 55.6 bits (128), Expect = 8e-06
 Identities = 64/270 (23%), Positives = 100/270 (37%), Gaps = 16/270 (5%)

Query: 254  DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313
            D SL+          E   E   +V    A G L   D P I+        E G++   T
Sbjct: 4250 DESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLT 4309

Query: 314  CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
             + T   E    W  E     + P  S +K+      +  T L I+  +  D +   VC 
Sbjct: 4310 TSITNAKEVN--WYFENK---LVP--SDEKFKCLQDQNTYT-LVIDKVNTEDHQGEYVCE 4361

Query: 374  AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF 433
            A+N +G +    KLTV     R  P+I        + +  +A F C     P     W+ 
Sbjct: 4362 ALNDSGKTATSAKLTVVK---RAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFK 4418

Query: 434  EGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
             G  + ++ + ++ +     +L +      D G YTC AS+ +G    +  L V     P
Sbjct: 4419 AGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPP 4478

Query: 491  NIHFFRAADVSSLPGPPTKPITHNVTDTSV 520
                 R   +++  G   K I   VT T V
Sbjct: 4479 TF-LSRPKSLTTFVGKAAKFIC-TVTGTPV 4506



 Score = 55.2 bits (127), Expect = 1e-05
 Identities = 51/186 (27%), Positives = 81/186 (43%), Gaps = 27/186 (14%)

Query: 425   PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
             P P + W  + GE+L +    + ++   L++ ++++ DSG Y     +  G    S +  
Sbjct: 22815 PAPEVKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSG----SKSAF 22870

Query: 484   VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543
             V+          R  D    PGPP       VT TSVTL+W      G S I  Y VE  
Sbjct: 22871 VN---------VRVLDT---PGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVE-- 22916

Query: 544   SRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
              RE+          + +  +A   H+T + V  L  G +Y F V  EN +G+  P+  ++
Sbjct: 22917 KRES--------TRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAE 22968

Query: 604   SVTVGD 609
             SV   +
Sbjct: 22969 SVKASE 22974



 Score = 55.2 bits (127), Expect = 1e-05
 Identities = 76/307 (24%), Positives = 117/307 (38%), Gaps = 36/307 (11%)

Query: 304   VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
             V +G  AR      GRP P + WS E        G   DK       +  T L+I++ D+
Sbjct: 24963 VRAGGSARIHIPFKGRPTPEITWSRE-------EGEFTDKVQIEKGVN-YTQLSIDNCDR 25014

Query: 364   NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
             ND+   I+    N +GS      +TV   D   PP        Q L +K +       + 
Sbjct: 25015 NDAGKYIL-KLENSSGSK--SAFVTVKVLDTPGPP--------QNLAVKEVRKDSAFLVW 25063

Query: 424   TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
              P PII    +G A ++N+  +          ++    S T   V +   G   +   + 
Sbjct: 25064 EP-PII----DGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMA 25118

Query: 484   VDS-PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEV 542
              +   +   +    A   +  P PP K    +V+ TS +L W +    G S +LGY VE+
Sbjct: 25119 ENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEM 25178

Query: 543   FSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602
                        P+ +  W ++A      + VV  L  G  Y F V+  N  G S P  + 
Sbjct: 25179 ----------QPKGTEKWSIVAES-KVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLG 25227

Query: 603   DSVTVGD 609
               V   D
Sbjct: 25228 VPVIAKD 25234



 Score = 54.8 bits (126), Expect = 1e-05
 Identities = 107/394 (27%), Positives = 160/394 (40%), Gaps = 60/394 (15%)

Query: 425   PEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYT-CVASSRHGKYVWSG 480
             P+  + W  +G+ L +  R NV++  T   L +K+  K D GTY  CV++S       +G
Sbjct: 26349 PQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNS-------AG 26401

Query: 481   ALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQV 540
             ++ V  PI           V   PGPP       V+  S+T+SW+     G   I  Y V
Sbjct: 26402 SITV--PIT--------IIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIV 26451

Query: 541   EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600
             E   +ET         S  W ++++ V +T   +  L  G  Y F V  EN +G S  S 
Sbjct: 26452 E--KKET--------TSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSE 26501

Query: 601   VSDSVTVGDDSNSLWEGT-GVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFY 659
              S  V     S     GT  V ++T  ++ +L    V + +     S+ I    E     
Sbjct: 26502 SSAVVAEYPFSPPGPPGTPKVVHAT--KSTMLVTWQVPVNDG---GSRVIGYHLE----- 26551

Query: 660   YLEGLFIYFRPLDNITI-EYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKP 718
             Y E   I +   + I I + +MK       VSG +   + +Y  Y   +        GK 
Sbjct: 26552 YKERSSILWSKANKILIADTQMK-------VSGLDEGLMYEYRVYAENIAGI-----GKC 26599

Query: 719   SNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPA 778
             S S       D P  PP   E+  +   +V LKWS P        ITGY  +V   ++P 
Sbjct: 26600 SKSCEPVPARD-PCDPPGQPEVTNITRKSVSLKWSKPHYD-GGAKITGY--IVERRELPD 26655

Query: 779   NKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAA 812
              +  +  N T  Q T   +T LT    Y  ++ A
Sbjct: 26656 GR-WLKCNYTNIQETYFEVTELTEDQRYEFRVFA 26688



 Score = 54.8 bits (126), Expect = 1e-05
 Identities = 97/440 (22%), Positives = 164/440 (37%), Gaps = 58/440 (13%)

Query: 389   VTSDDDRPPPIITNGPSN-QTLPIKSMAVFPCTAICT--PEPIIAWYFEGEALIQNHRRN 445
             + + D+  PPI+  GP     L IKS       A+    P P + W+ +G  + +     
Sbjct: 28874 IMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNME 28933

Query: 446   VTN---DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSS 502
             +T+     +L ++D  +   G YT  A +       SG+   +  +           V  
Sbjct: 28934 ITDVLGSTSLFVRDATRDHRGVYTVEAKNA------SGSAKAEIKVK----------VQD 28977

Query: 503   LPGPPTKPITH-NVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV 561
              PG    PI   N+T   +TL W      G + I  Y +E   RET        +   W 
Sbjct: 28978 TPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIE--KRET--------SRLAWA 29027

Query: 562   VIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVS 621
             +I  +     Y    LI G  Y F V   N  G+    P+     V     ++ +  G+ 
Sbjct: 29028 LIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVG--RPLDSDPVVAQIQYTVPDAPGIP 29085

Query: 622   NSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMK 681
               +      +T + + L  A P      ++   IL               +  +  +   
Sbjct: 29086 EPSN-----ITGNSITLTWARPESDGGSEIQQYILE------------RREKKSTRWVKV 29128

Query: 682   TILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN-SRVAQTLDDV-PDGPPINIE 739
                     + F++T L +  +YEF ++       G  S  SR+ +  + V P GPP  ++
Sbjct: 29129 ISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVK 29188

Query: 740   MFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTN 799
             +   + TTV L+WS P       II GY + +   D+        +N      T   +T+
Sbjct: 29189 VTDTSKTTVSLEWSKPVFDGGMEII-GYIIEMCKADL---GDWHKVNAEACVKTRYTVTD 29244

Query: 800   LTSGVSYSVQIAAETIIGLG 819
             L +G  Y  +++A    G G
Sbjct: 29245 LQAGEEYKFRVSAINGAGKG 29264



 Score = 54.4 bits (125), Expect = 2e-05
 Identities = 49/189 (25%), Positives = 70/189 (37%), Gaps = 13/189 (6%)

Query: 293  PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV-FD 351
            P   L P S     G  ARF     GRP P  FW  +G + +       D  H   +  D
Sbjct: 1457 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIV------NDYTHKVVIKED 1510

Query: 352  GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
            G   L I     +DS    V  A N AG S +   LTV + + +  P+      N  +  
Sbjct: 1511 GTQSLIIVPATPSDSGEWTVV-AQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKE 1569

Query: 412  KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-----LVLKDLDKSDSGTYT 466
             S       A   P P I W    + ++ +    +  +GT     L +      DS  YT
Sbjct: 1570 GSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYT 1629

Query: 467  CVASSRHGK 475
              A ++ G+
Sbjct: 1630 ATAINKAGR 1638



 Score = 54.0 bits (124), Expect = 2e-05
 Identities = 54/222 (24%), Positives = 85/222 (38%), Gaps = 29/222 (13%)

Query: 389   VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT--PEPIIAWYFEGEALIQNHRRNV 446
             +  + +  P    +    +TL +K+ A F  T      P P + W      L      + 
Sbjct: 27103 IAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDT 27162

Query: 447   TNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPG 505
             T+  T L +++ +++DSG YT    +     V S A L                V   PG
Sbjct: 27163 TDSRTSLTIENANRNDSGKYTLTIQN-----VLSAASLT-----------LVVKVLDTPG 27206

Query: 506   PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565
             PPT     +VT  S  LSW      G + +  Y +E   RE         + + WV +  
Sbjct: 27207 PPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIE--KREA--------SKKAWVSVTN 27256

Query: 566   RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
               ++  Y V +L  G  Y F V  EN  G+  P+   + V +
Sbjct: 27257 NCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKI 27298



 Score = 54.0 bits (124), Expect = 2e-05
 Identities = 98/409 (23%), Positives = 156/409 (38%), Gaps = 59/409 (14%)

Query: 425   PEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHG-KYVWSG 480
             PEP I W    + L    + ++   G   T V+K  D+SDSG YT    +  G K V   
Sbjct: 30002 PEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVM 30061

Query: 481   ALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQV 540
               ++DSP                 GP  K     VT    TL+WS   + G + I  Y V
Sbjct: 30062 VKVLDSP-----------------GPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIV 30104

Query: 541   EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600
             E   RET   N        WV++        YVV  LI    Y+F VR  N +G     P
Sbjct: 30105 E--RRETSRLN--------WVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPG--VP 30152

Query: 601   VSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYY 660
             V     V  +S ++    G+            +HI+  I+ T  +S       EI N+  
Sbjct: 30153 VESEPIVARNSFTIPSPPGIPEEV----GTGKEHII--IQWTKPESDGGN---EISNYLV 30203

Query: 661   --LEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKP 718
                E   + +  ++   + Y+ +           ++TSL +   Y+F +         +P
Sbjct: 30204 DKREKKSLRWTRVNKDYVVYDTR----------LKVTSLMEGCDYQFRVTAVNAAGNSEP 30253

Query: 719   SNSR--VAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDV 776
             S +   ++        GPP    +      ++ L W+ P       I+ GY + +   D 
Sbjct: 30254 SEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIV-GYVLEMQEKDT 30312

Query: 777   PANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
                   V  N T+   T   + +L  G  YS ++AA  + G+  +S+ +
Sbjct: 30313 D-QWYRVHTNATIRN-TEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESI 30359



 Score = 53.6 bits (123), Expect = 3e-05
 Identities = 50/186 (26%), Positives = 78/186 (41%), Gaps = 27/186 (14%)

Query: 425   PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKD-LDKSDSGTYTCVASSRHGKYVWSGALL 483
             P P+I W  +G  L      + T   +L++ D +++ D+G YT  A ++ GK   S  +L
Sbjct: 30401 PPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKK--SATVL 30458

Query: 484   VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543
             V               V   PGP        V+  SVT++W      G + +  Y VE  
Sbjct: 30459 V--------------KVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVE-- 30502

Query: 544   SRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
              RE           R +  +  +  +T Y +  L+ G  Y F V  EN +G+  P   SD
Sbjct: 30503 KREAA--------MRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSD 30554

Query: 604   SVTVGD 609
             +V V +
Sbjct: 30555 AVLVSE 30560



 Score = 53.6 bits (123), Expect = 3e-05
 Identities = 73/376 (19%), Positives = 145/376 (38%), Gaps = 24/376 (6%)

Query: 119   SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGR 177
             +   D+V    +   G P P   W K+G+ +   G  ++    GG  L I     +D+G 
Sbjct: 33789 TVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGL 33848

Query: 178   YQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
             Y C  +N+AG   S  ++ K+ IK    T  + V  Q  S +T Q +     + + + ++
Sbjct: 33849 YTCTVKNSAG---SVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKA---VVQEEISQK 33902

Query: 238   SAGGGNMPLGRVKVLDDGSLR--LDNVILADEGEYSC--EAENSV--GAVSASGYLTVYD 291
             +     + +   K  +  +L+     V++++E + S     E S+    ++ +   +   
Sbjct: 33903 ALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEV 33962

Query: 292   PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
                  +   S  +      R    A       + W + G        ++  + +   V  
Sbjct: 33963 RTHAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVE------LTNSEEYRYGVSG 34016

Query: 352   GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
                 LTI      D    + C +    G    +  LT++ +    P  I+  P +Q +  
Sbjct: 34017 SDQTLTIKQASHRD-EGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQ-PRSQNINE 34074

Query: 412   KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCV 468
                 +F C     P P I W+     +  +   +++   N  +L +++   SDSG YT  
Sbjct: 34075 GQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIK 34134

Query: 469   ASSRHGKYVWSGALLV 484
             A +  G+   + +L+V
Sbjct: 34135 AKNFRGQCSATASLMV 34150



 Score = 53.2 bits (122), Expect = 4e-05
 Identities = 35/118 (29%), Positives = 49/118 (41%), Gaps = 5/118 (4%)

Query: 177  RYQCIARNAAGTRESAIATLKIHIK---PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233
            R++ +    A   E+A     + I    P L++G ++V    G SVT +C + G P P V
Sbjct: 915  RFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTV 974

Query: 234  LWRRSAGGGNMPLGRVKVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTV 289
             W R        +        G  RL        D G ++C A N  G VS S YL V
Sbjct: 975  TWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032



 Score = 53.2 bits (122), Expect = 4e-05
 Identities = 35/102 (34%), Positives = 47/102 (46%), Gaps = 10/102 (9%)

Query: 504   PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
             P PP KP   +V  TSV L+W++    G + I  Y +E+    T            WV +
Sbjct: 14911 PWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDE----------WVRV 14960

Query: 564   ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605
             A  V  T +++  L+ G  Y F VR  N  G S PS  SD V
Sbjct: 14961 AEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPV 15002



 Score = 53.2 bits (122), Expect = 4e-05
 Identities = 29/95 (30%), Positives = 47/95 (49%), Gaps = 4/95 (4%)

Query: 198   IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS- 256
             I  KP ++TG +D    + S   F  +  G+P P  +W +  G      G+ K+ +D   
Sbjct: 33775 ISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKD-GKAITQGGKYKLSEDKGG 33833

Query: 257   --LRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
               L +     +D G Y+C  +NS G+VS+S  LT+
Sbjct: 33834 FFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 33868



 Score = 52.8 bits (121), Expect = 5e-05
 Identities = 101/478 (21%), Positives = 180/478 (37%), Gaps = 46/478 (9%)

Query: 13   YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRAT 72
            + + +P  + V     AT   + GG P P ++W KG    ++   R  +   G       
Sbjct: 9382 FFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEI 9441

Query: 73   HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP 132
                 +D+G+Y C A N +G   S N  L V   +++ ++E + +   +  T +L+    
Sbjct: 9442 RDTTKTDSGLYRCVAFNEHGEIES-NVNLQVDERKKQEKIEGDLRAMLK-KTPILKKGAG 9499

Query: 133  RGSPEPNVYWKKNGQTLLFDGDSRMH-LVDGGNLV-----IQDARQTDAGRYQCIARNAA 186
                   +   KN     ++  +RM+ + D   L+     ++ +++ +  R +      +
Sbjct: 9500 EEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFELLKQSQEEETHRLEIEEIERS 9559

Query: 187  GTRESAIATLKIHIKPYL-----ITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRS 238
               E     L   I+  L     +T  +D+  QT    +   F+  +  +  P++     
Sbjct: 9560 ERDEKEFEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDAVFEIDIKIN-YPEIKLSWY 9618

Query: 239  AGGGNM-PLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
             G   + P  + ++  DG   +LR+ N  L D+G Y        G   AS  LTV +P +
Sbjct: 9619 KGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVC----GPHIASAKLTVIEP-A 9673

Query: 295  INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
                   V ++ G     TC  +  P     W   G    I     R   H T V   V 
Sbjct: 9674 WERHLQDVTLKEGQTCTMTCQFSV-PNVKSEWFRNGR---ILKPQGR---HKTEVEHKVH 9726

Query: 355  VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
             LTI D    D +    C   +   S+ +R         +  P   T    N  +     
Sbjct: 9727 KLTIADVRAED-QGQYTCKYEDLETSAELR--------IEAEPIQFTKRIQNIVVSEHQS 9777

Query: 415  AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVA 469
            A F C  +   + I+ WY     L ++ + N  NDG    + + ++   D G Y+ +A
Sbjct: 9778 ATFECE-VSFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIA 9834



 Score = 52.8 bits (121), Expect = 5e-05
 Identities = 44/129 (34%), Positives = 55/129 (42%), Gaps = 14/129 (10%)

Query: 484   VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE-- 541
             +  P  P+   F A D  + P PP  P   + T  SV L+W      G S ILGY VE  
Sbjct: 18021 IGDPSPPSKPVF-AKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQ 18079

Query: 542   -VFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600
              V   E    N+TP +            +T Y V  L  G TY F V   N+ G S P+ 
Sbjct: 18080 KVGDEEWRRANHTPES----------CPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAH 18129

Query: 601   VSDSVTVGD 609
             V + V V D
Sbjct: 18130 VPEPVLVKD 18138



 Score = 52.8 bits (121), Expect = 5e-05
 Identities = 70/320 (21%), Positives = 117/320 (36%), Gaps = 33/320 (10%)

Query: 293   PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
             PS+ L  N+ ++++G   +      GRP P + W  +G         +R     TA    
Sbjct: 25239 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEP---LKQTTRVNVEETATS-- 25293

Query: 353   VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
              TVL I + +K+D     V +A N AG++     + V      P   +     +    + 
Sbjct: 25294 -TVLHIKEGNKDDFGKYTV-TATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVI 25351

Query: 413   SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
             S      T  C     I    +      +         T+ +  L       +   A +R
Sbjct: 25352 SWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENR 25411

Query: 473   HGKY--VWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530
             +GK   + S A++V  P                PGPP  P   +++   + + W +    
Sbjct: 25412 YGKSAPLDSKAVIVQYPFKE-------------PGPPGTPFVTSISKDQMLVQWHEPVND 25458

Query: 531   GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMFIVRT 589
             G + I+GY +E             +NS  WV + +  +  T +    L  G+ Y F V  
Sbjct: 25459 GGTKIIGYHLE----------QKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSA 25508

Query: 590   ENSHGLSGPSPVSDSVTVGD 609
             EN  G+  PS VS+     D
Sbjct: 25509 ENIVGIGKPSKVSECFVARD 25528



 Score = 52.4 bits (120), Expect = 7e-05
 Identities = 36/129 (27%), Positives = 57/129 (44%), Gaps = 7/129 (5%)

Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA---GGGNMPLGRVKVLDD-GSLRLDNVIL 264
           + VV   GS+ TF+  + G P+P+V W R         +P  ++   D    L +  V  
Sbjct: 13  QSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTK 72

Query: 265 ADEGEYSCEAENSVGAVSASGYLTV---YDPPSINLSPNSVNVESGNVARFTCTATGRPE 321
           A+ G YS +A N  G  +++  L V     PP+      S+ V  G+  R     TG P 
Sbjct: 73  ANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPT 132

Query: 322 PTMFWSVEG 330
           P + +  +G
Sbjct: 133 PVVKFYRDG 141



 Score = 52.4 bits (120), Expect = 7e-05
 Identities = 34/108 (31%), Positives = 50/108 (46%), Gaps = 10/108 (9%)

Query: 496   RAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPR 555
             RA D   LP PP+KP   +   T++T++W +    G + I GY VE    +      + +
Sbjct: 27003 RAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQ 27062

Query: 556   NSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
             + RG          T Y +  L  G  Y+F V++ N  G S PS  SD
Sbjct: 27063 SLRG----------TEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSD 27100



 Score = 52.0 bits (119), Expect = 1e-04
 Identities = 51/198 (25%), Positives = 77/198 (38%), Gaps = 10/198 (5%)

Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDG--DSRMHLVDG-GNLVIQDARQTDAGR 177
           +G T   E     G P P V W ++GQ +        ++   DG   L I    + ++GR
Sbjct: 19  EGSTATFEA-HISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGR 77

Query: 178 YQCIARNAAGTRESAIATL-KIHIKP-YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
           Y   A N +G   S    L K    P   +   + +  + GS V  Q RV G P P V +
Sbjct: 78  YSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKF 137

Query: 236 RRSAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
            R        L   ++  +G   SL +      D G YS  A NSVG  +++  L V   
Sbjct: 138 YRDGAEIQSSLD-FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGE 196

Query: 293 PSINLSPNSVNVESGNVA 310
             +        V +  ++
Sbjct: 197 EEVPAKKTKTIVSTAQIS 214



 Score = 52.0 bits (119), Expect = 1e-04
 Identities = 103/442 (23%), Positives = 168/442 (38%), Gaps = 42/442 (9%)

Query: 38    SPSPAIR-WYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
             SPS AI  W K G  +        +  G    L     ++ SDAG Y C         ++
Sbjct: 12070 SPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQL-SDAGEYTC-VLRLGNKEKT 12127

Query: 97    RNATLHVAVLREEF-RLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155
               A L V  L   F +   E     +G  + L C     + E +V W+K+G+ ++     
Sbjct: 12128 STAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSC---ELNKERDVVWRKDGKIVVEKPGR 12184

Query: 156   RMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVA 213
              +  V G    L I DA  TDAG Y     NA     S+   +   I+ +L+    D   
Sbjct: 12185 IVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKPIRDQHV 12244

Query: 214   QTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDGS---LRLDNVILADEGE 269
             +   +  F C +  D  P++ W +        P  + ++L DG+   L++ N +  D  E
Sbjct: 12245 KPKGTAIFACDIAKD-TPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAE 12303

Query: 270   YSCEAENSVGAVSASGYLTVYDPPSINLSP-NSVNVESGNVARFTCTATGRPEPTMFWSV 328
             Y+ E E           LT+ +     L P   V +     A F    +    P   W +
Sbjct: 12304 YAVEIEGK----RYPAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQ-WKL 12358

Query: 329   EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT 388
             +G   ++ P  + +         G   LT+    K D    ++  A+N    +     LT
Sbjct: 12359 KGE--LLRPSPTCE----IKAEGGKRFLTLRKV-KLDQAGEVLYQALN----AITTAILT 12407

Query: 389   VTSDD-DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT 447
             V   + D   P+      + T+P +  A F C  + T E  + W    + +  + + ++ 
Sbjct: 12408 VKEIELDFAVPL-----KDVTVPERRQARFEC--VLTREANVIWSKGPDIIKSSDKFDII 12460

Query: 448   NDG---TLVLKDLDKSDSGTYT 466
              DG    LV+ D    D G YT
Sbjct: 12461 ADGKKHILVINDSQFDDEGVYT 12482



 Score = 52.0 bits (119), Expect = 1e-04
 Identities = 83/351 (23%), Positives = 137/351 (39%), Gaps = 51/351 (14%)

Query: 269   EYSCEAENSVGAVSA----SGYLTVYDP---PSINLS---PNSVNVESGNVARFTCTATG 318
             E+   A+N+ GA+S     S  +T  D    P I +     ++V +++G   R     +G
Sbjct: 22355 EFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSG 22414

Query: 319   RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
             RP PTM WS +G       G ++ +     + D  T L   D+ + DS      +A N  
Sbjct: 22415 RPPPTMEWSKDGKE---LEGTAKLEIK---IADFSTNLVNKDSTRRDS-GAYTLTATNPG 22467

Query: 379   GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY---FEG 435
             G  F +    V   D   PP    GP         +AV   T + + + +++W+    +G
Sbjct: 22468 G--FAKHIFNVKVLDRPGPP---EGP---------LAV---TEVTSEKCVLSWFPPLDDG 22510

Query: 436   EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG-KYVWSGALLVDSPINPNIHF 494
              A I ++         L   ++      T   V     G +Y++    +    +   +  
Sbjct: 22511 GAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLES 22570

Query: 495   FRAADVSSL--PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNN 552
                  V+    P PP  P    +T  S+ + W   +  G S I+ Y VE   R   +G  
Sbjct: 22571 EPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVE---RRDKAGQR 22627

Query: 553   TPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602
                    W+   ++ +    Y V  L  G  Y F +  EN+ G+S PSP S
Sbjct: 22628 -------WIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTS 22671



 Score = 52.0 bits (119), Expect = 1e-04
 Identities = 49/176 (27%), Positives = 74/176 (42%), Gaps = 30/176 (17%)

Query: 425   PEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
             P P + W+ +   L Q  R N     N+  L +KD  + D G Y    ++  G+ + +  
Sbjct: 23102 PTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLN 23161

Query: 482   LLVDSPINPNIHFFRAADVSSLPGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSILGYQV 540
             ++V                   PGPPT P+  + VT  S+TLSW      G SSI  Y V
Sbjct: 23162 VIV----------------LDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIV 23205

Query: 541   EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
             E   R+T        ++  W +++  V +T      L  G  Y F +  EN +G S
Sbjct: 23206 E--KRDT--------STTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKS 23251



 Score = 51.6 bits (118), Expect = 1e-04
 Identities = 34/110 (30%), Positives = 45/110 (40%), Gaps = 9/110 (8%)

Query: 500   VSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRG 559
             V   PGPP   +  ++  TSV   W      G S I+ Y        TL   +  +    
Sbjct: 15725 VLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINY--------TLEKKDKTKPDSE 15776

Query: 560   WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
             W+V+   +    Y V  LI G  Y+F VR EN  G  GP  VS  +   D
Sbjct: 15777 WIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFG-PGPPCVSKPLVAKD 15825



 Score = 51.6 bits (118), Expect = 1e-04
 Identities = 52/192 (27%), Positives = 74/192 (38%), Gaps = 14/192 (7%)

Query: 292   PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
             PP   L   +     G   RF  T T  PEP + W   G +  I PG   DK +      
Sbjct: 32616 PPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQK--IKPG-DNDKKYTFESDK 32672

Query: 352   GVTVLTIND-TDKNDSRNTIVCSAVNYAGSSFVRGKLTVT----SDDDRPPPIITNGPSN 406
             G+  LTIN  T  +D+  T+V  A N  G    + KLTVT      D    P+     +N
Sbjct: 32673 GLYQLTINSVTTDDDAEYTVV--ARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLAN 32730

Query: 407   QTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG----TLVLKDLDKSDS 462
                       F       P P + W  +G+ L       + ++G     L ++D    D+
Sbjct: 32731 AECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDT 32790

Query: 463   GTYTCVASSRHG 474
             G Y   A++  G
Sbjct: 32791 GYYRVTATNTAG 32802



 Score = 51.2 bits (117), Expect = 2e-04
 Identities = 30/99 (30%), Positives = 47/99 (47%), Gaps = 3/99 (3%)

Query: 391  SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG 450
            S+ +   PI     SN  + +  +A    T I  P+P I W+F G  L  +       DG
Sbjct: 3496 SEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDG 3555

Query: 451  ---TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
               +L++      D G YTC+AS+ +GK + S  L ++S
Sbjct: 3556 DDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINS 3594



 Score = 50.8 bits (116), Expect = 2e-04
 Identities = 74/318 (23%), Positives = 120/318 (37%), Gaps = 36/318 (11%)

Query: 302   VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
             + V++G       T TG+PEP + W+      +I   + +DK          + +TI D+
Sbjct: 14627 LTVKAGTKIELPATVTGKPEPKITWT---KADMI---LKQDKRITIENVPKKSTVTIVDS 14680

Query: 362   DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
              ++D+  T +  AVN  G +    ++ V      P        +N++     +  +    
Sbjct: 14681 KRSDT-GTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESC----LLTWNPPR 14735

Query: 422   ICTPEPIIAWYFEGEALIQN--HRRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGKYVW 478
                   I  +  E  A      H+ + T  D       L  +    +   A + +G    
Sbjct: 14736 DDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGV--- 14792

Query: 479   SGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGY 538
              G  +  SPI     F         PGPPT+    ++T  +VTL+W + +  G S I GY
Sbjct: 14793 -GEPVQASPITAKYQF-------DPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGY 14844

Query: 539   QVEVFSRETLSGNNTPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSG 597
              VE    +T            WV   +  V  T Y VK L     Y F V  EN  G   
Sbjct: 14845 WVERLDPDT----------DKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGK 14894

Query: 598   PSPVSDSVTVGDDSNSLW 615
             PS  ++ + + D  +  W
Sbjct: 14895 PSKSTEPILIKDPIDPPW 14912



 Score = 50.8 bits (116), Expect = 2e-04
 Identities = 97/407 (23%), Positives = 161/407 (39%), Gaps = 63/407 (15%)

Query: 425   PEPIIAWYFEGEALIQNH--RRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
             P+P I+W  +G  L ++   R + T N  TL +K+  K   G YT +  +   +      
Sbjct: 28518 PKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPIT 28577

Query: 482   LLVDSPINPNIHFFRAADVSSLPGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSILGYQV 540
             ++   P                P  P  PI  + +   SV LSW      G   I  Y +
Sbjct: 28578 VITLGP----------------PSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSI 28621

Query: 541   EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600
             E   RET   N        W ++   V +T + V +L+    Y F VR EN +G+S   P
Sbjct: 28622 E--KRETSQTN--------WKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVS--QP 28669

Query: 601   VSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYY 660
             +  S+ V      +    G      Y  N+ +D +    +A   D  +     E+  F+ 
Sbjct: 28670 LVSSIIVAKHQFRIPGPPG--KPVIY--NVTSDGMSLTWDAPVYDGGS-----EVTGFHV 28720

Query: 661   LEGLFIYFRPLDNITIEYEMKTILHSNDVSG--FEITSLRKYTKYEFFLIPFYKKFEGKP 718
                        +  +I ++    ++++ +SG  +  T L +   Y+F +  + +   G  
Sbjct: 28721 --------EKKERNSILWQK---VNTSPISGREYRATGLVEGLDYQFRV--YAENSAGLS 28767

Query: 719   SNSRVAQ-TLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVP 777
             S S  ++ TL   P  PP   +   +   T+ LKW+PP L+     I GY++        
Sbjct: 28768 SPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPP-LRDGGSKIVGYSIEKR----Q 28822

Query: 778   ANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIG-LGPFSQ 823
              N+  V  N T        +T L+ G  Y  +I A   +G + P SQ
Sbjct: 28823 GNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQ 28869



 Score = 50.0 bits (114), Expect = 4e-04
 Identities = 38/109 (34%), Positives = 47/109 (43%), Gaps = 11/109 (10%)

Query: 501   SSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGW 560
             S  P PP K    +VT  SV+LSW +    G S ILGY VE+            + S  W
Sbjct: 22973 SERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEM----------QTKGSDKW 23022

Query: 561   VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
                A  V  T   +  LI G  Y F V  +N  G+S P  +S  V   D
Sbjct: 23023 ATCA-TVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKD 23070



 Score = 50.0 bits (114), Expect = 4e-04
 Identities = 80/346 (23%), Positives = 137/346 (39%), Gaps = 41/346 (11%)

Query: 269   EYSCEAENSVGAVS----ASGYLTVYDP---PSINLSP---NSVNVESGNVARFTCTATG 318
             E+   A+N+ GA+S    ++G +T  D    P I++ P   +++ V +G   R      G
Sbjct: 24519 EFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHG 24578

Query: 319   RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
             +P PT+ W + G++ I     +R +   T   D   +L + D  + D    I+  A N A
Sbjct: 24579 KPLPTIEW-LRGDKEI--EESARCEIKNT---DFKALLIVKDAIRIDGGQYIL-RASNVA 24631

Query: 379   GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438
             GS      + V    DRP      GP    + +  +    C+   +P P+     +    
Sbjct: 24632 GSKSFPVNVKVL---DRP------GPPEGPVQVTGVTSEKCSLTWSP-PLQDGGSDISHY 24681

Query: 439   IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS-GALLVDSPINPNIHFFRA 497
             +   R       T+V  ++  +       +  + +   + +     V  P+       + 
Sbjct: 24682 VVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKN 24741

Query: 498   ADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNS 557
               V  LPGPP      N+   S+T+ W++ +  G S I+GY VE             R+ 
Sbjct: 24742 PFV--LPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVE----------KRDRSG 24789

Query: 558   RGWVVI-ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602
               W+    RR+      V  L     Y F V  EN+ G+  PSP +
Sbjct: 24790 IRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPAT 24835



 Score = 49.6 bits (113), Expect = 5e-04
 Identities = 35/117 (29%), Positives = 48/117 (41%), Gaps = 11/117 (9%)

Query: 494   FFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNT 553
             F + AD    P PP    + + T +SV L W    K G S ILGY +E            
Sbjct: 14209 FVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIE----------RC 14258

Query: 554   PRNSRGWV-VIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
                   W+    + V +  Y V  L  G  Y++ V  EN  G+S PS +   +T  D
Sbjct: 14259 EEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADD 14315



 Score = 49.6 bits (113), Expect = 5e-04
 Identities = 59/242 (24%), Positives = 89/242 (36%), Gaps = 23/242 (9%)

Query: 374   AVNYAGSSF---VRGKLTVTSDDDRPPPIITNGPSNQTL-PIKSMAVFPCTAICTPEPII 429
             AVN AG S      G++  T   + P   I  G  +  +    S    P      P P  
Sbjct: 16710 AVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKS 16769

Query: 430   AWYFEGEA--LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
             +W F+G+A   +++   ++  D  L  +  + S          S  GKY    ++   + 
Sbjct: 16770 SWEFDGKAKKAMKDGVHDIPEDAQL--ETAENSSVIIIPECKRSHTGKY----SITAKNK 16823

Query: 488   INPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRET 547
                     R   V  +PGPP      ++T  S  LSW   +  G   I GY +E   + T
Sbjct: 16824 AGQKTANCRVK-VMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIE---KRT 16879

Query: 548   LSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
             + G       + W  +      T +VV  L+    Y F VR EN  G+  P       T 
Sbjct: 16880 IDG-------KAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTA 16932

Query: 608   GD 609
              D
Sbjct: 16933 RD 16934



 Score = 49.6 bits (113), Expect = 5e-04
 Identities = 32/108 (29%), Positives = 49/108 (45%), Gaps = 11/108 (10%)

Query: 503   LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
             +PGPP  P+    +  S+ + W++    G S ++GY +E             RNS  WV 
Sbjct: 23267 VPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLE----------RKERNSILWVK 23316

Query: 563   IARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
             + +  + QT +    L  G+ Y F V  EN  G+  PS VS+     D
Sbjct: 23317 LNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARD 23364



 Score = 49.2 bits (112), Expect = 7e-04
 Identities = 31/90 (34%), Positives = 39/90 (43%), Gaps = 4/90 (4%)

Query: 202  PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGGGNMPLGRVKVLDDGSL 257
            PY IT P       G SV F C+VGG+P P V W++S      G    +   K   +  L
Sbjct: 1082 PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKL 1141

Query: 258  RLDNVILADEGEYSCEAENSVGAVSASGYL 287
             +      D GEY+    N  G  SAS  L
Sbjct: 1142 VISMTFADDAGEYTIVVRNKHGETSASASL 1171



 Score = 49.2 bits (112), Expect = 7e-04
 Identities = 52/179 (29%), Positives = 71/179 (39%), Gaps = 32/179 (17%)

Query: 425   PEPIIAWYF-EGEALIQNHR--RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
             P P   W   E E +  +H       +   L++KD+ + DSG Y+  A +  G       
Sbjct: 19853 PHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIK 19912

Query: 482   LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDT-SVTLSWSQNNKIGSSSILGYQV 540
             ++                V   PGPP  P   +  D  + +LSW    + G S+I  Y V
Sbjct: 19913 VV----------------VMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIV 19956

Query: 541   EVFSRETLSGNNTPRNSRG-WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
             E               SRG WV     V +T   V  LIPG  Y+F VR EN  G+S P
Sbjct: 19957 EKCD-----------VSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEP 20004



 Score = 49.2 bits (112), Expect = 7e-04
 Identities = 97/385 (25%), Positives = 146/385 (37%), Gaps = 41/385 (10%)

Query: 178   YQCIARNAAG-----TRESAIATLKIHIKPYLIT-GP---EDVVAQTGSSVTFQCRVGGD 228
             ++ IARNAAG     +  +   T +  + P  I+  P   + +V   G S      + G 
Sbjct: 23438 FRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGK 23497

Query: 229   PLPDVLWRRSAGG-GNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGY 286
             P+P + W +      N     +K  D   SL + + +  D G Y  +A+N  G  S +  
Sbjct: 23498 PIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVN 23557

Query: 287   LTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR---DK 343
             + V D P     P    V SG  A   CT   +P P      +G   II   + R    +
Sbjct: 23558 VKVLDRPG---PPEGPVVISGVTAE-KCTLAWKP-PLQ----DGGSDIINYIVERRETSR 23608

Query: 344   YHATAVFDGVTVLTINDTDKNDSRN-TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN 402
                T V   V  L+   T   +    T    AVN  G         V + +    P    
Sbjct: 23609 LVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPK 23668

Query: 403   GPSNQTLPIKSM-AVFPCTAICTPEPIIAWYF-----EGEALIQNHRRNVTNDGTLVLKD 456
              P   T+   SM  V+   A      I+ +       EG    + H+R +   G L L+ 
Sbjct: 23669 APEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLI---GELRLRV 23725

Query: 457   LDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVT 516
                 ++  Y    S+ +       A  +  P  P+  + +A D    PGPP  P   ++T
Sbjct: 23726 TGLIENHDYEFRVSAEN-------AAGLSEPSPPSA-YQKACDPIYKPGPPNNPKVIDIT 23777

Query: 517   DTSVTLSWSQNNKIGSSSILGYQVE 541
              +SV LSWS+    G   I GY VE
Sbjct: 23778 RSSVFLSWSKPIYDGGCEIQGYIVE 23802



 Score = 48.8 bits (111), Expect = 9e-04
 Identities = 64/264 (24%), Positives = 102/264 (38%), Gaps = 33/264 (12%)

Query: 20    DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
             DVTV   + A   C      +  + W KG  ++ S     I+ A G   +   +     D
Sbjct: 12421 DVTVPERRQARFECVLTREAN--VIWSKGPDIIKSSDKFDII-ADGKKHILVINDSQFDD 12477

Query: 80    AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
              GVY  E      +AR     L V  +R +F    E +   +G+T    C       + +
Sbjct: 12478 EGVYTAEVEGKKTSAR-----LFVTGIRLKFMSPLEDQTVKEGETATFVC--ELSHEKMH 12530

Query: 140   VYWKKN------GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
             V W KN       +T+L   + + H ++   + + D  Q  A   +           S+ 
Sbjct: 12531 VVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKEL----------SST 12580

Query: 194   ATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL 252
             A LK+    PY      D  A     +T +C V  D +P V W +  G   +P  +  + 
Sbjct: 12581 AQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKD-VP-VKWFKD-GEEIVPSPKYSIK 12637

Query: 253   DDGS---LRLDNVILADEGEYSCE 273
              DG    L++    L D+GEY C+
Sbjct: 12638 ADGLRRILKIKKADLKDKGEYVCD 12661



 Score = 48.8 bits (111), Expect = 9e-04
 Identities = 86/376 (22%), Positives = 146/376 (38%), Gaps = 62/376 (16%)

Query: 251   VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD------PPSINLSPNSVNV 304
             V+ D SL +  +    + ++   A N+VG         VY+      PP I L P  + +
Sbjct: 19779 VVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKI-LMPEQITI 19837

Query: 305   ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
             ++G   R      G+P PT  W  +G   ++        + A    D  ++L I D  + 
Sbjct: 19838 KAGKKLRIEAHVYGKPHPTCKWK-KGEDEVV-----TSSHLAVHKADSSSILIIKDVTRK 19891

Query: 365   DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
             DS      +A N +G+   + K+ V    D P      GP      I  +    C+    
Sbjct: 19892 DS-GYYSLTAENSSGTDTQKIKVVVM---DAP------GPPQPPFDISDIDADACS---- 19937

Query: 425   PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS-----SRHGKYV-- 477
                 ++W+      +++   N+TN    +++  D S     T +AS      R GK +  
Sbjct: 19938 ----LSWHIP----LEDGGSNITN---YIVEKCDVSRGDWVTALASVTKTSCRVGKLIPG 19986

Query: 478   --WSGALLVDSPINPNIHFFRAADVSSLP-GPPTKPITHNVTDTS---VTLSWSQNNKIG 531
               +   +  ++    +        V+  P G P++P    VT  +   + ++W + +  G
Sbjct: 19987 QEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDG 20046

Query: 532   SSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMFIVRTE 590
              S I+GY +E             RNS  WV      V  T Y    L+ G+ Y F +   
Sbjct: 20047 GSPIIGYLIE----------RKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYAL 20096

Query: 591   NSHGLSGPSPVSDSVT 606
             N  G S PS  ++ VT
Sbjct: 20097 NKAGSSPPSKPTEYVT 20112



 Score = 48.8 bits (111), Expect = 9e-04
 Identities = 34/108 (31%), Positives = 49/108 (45%), Gaps = 11/108 (10%)

Query: 504   PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV-V 562
             PG P KP    VT  S  ++W      G + I  Y +E   RE        +    W+ V
Sbjct: 31752 PGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLE--KRE--------KKQNKWISV 31801

Query: 563   IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDD 610
                 + +T + VK+LI G+ Y F V+ EN  G S  S +S+ +T   D
Sbjct: 31802 TTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSD 31849



 Score = 48.4 bits (110), Expect = 0.001
 Identities = 39/114 (34%), Positives = 53/114 (46%), Gaps = 12/114 (10%)

Query: 497   AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556
             A D    P  P KPI  +VT  S+ + W++    GS  ILGY +E   RE         N
Sbjct: 15823 AKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSP-ILGYWLE--KREV--------N 15871

Query: 557   SRGWVVIARRV-HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
             S  W  + + + +     V  L+ G+TY+F V  EN+ G    SP SD  T  D
Sbjct: 15872 STHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHD 15925



 Score = 47.6 bits (108), Expect = 0.002
 Identities = 34/97 (35%), Positives = 50/97 (51%), Gaps = 6/97 (6%)

Query: 122   GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL---VDGGNLVIQDARQTDAGRY 178
             G+T VLE    RG P P+V W K+G+  L +  +RM +   +    LV++D  +TD G+Y
Sbjct: 25649 GETFVLEA-DIRGKPIPDVVWSKDGKE-LEETAARMEIKSTIQKTTLVVKDCIRTDGGQY 25706

Query: 179   QCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT 215
                  N  GT+   I T+K+  +P    GP  V   T
Sbjct: 25707 ILKLSNVGGTKSIPI-TVKVLDRPGPPEGPLKVTGVT 25742



 Score = 47.2 bits (107), Expect = 0.003
 Identities = 54/218 (24%), Positives = 82/218 (37%), Gaps = 27/218 (12%)

Query: 4    DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
            D    G  P  I++  +  ++    ATL+    G P P I+W+  GVL+        +  
Sbjct: 3495 DSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFD 3554

Query: 64   GGLFFLRATHGRVHSDAGVYWCEATNSYGTA-------------RSRNATLHVAVLRE-- 108
            G    L     ++  D G Y C A+N YG                 ++     AV +   
Sbjct: 3555 GDDHSLIILFTKL-EDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLE 3613

Query: 109  --------EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHL 159
                     F  E +  + AQG   + E     G P P V W K+N Q       + +H 
Sbjct: 3614 KLGGPCPPHFLKELKPIRCAQGLPAIFE-YTVVGEPAPTVTWFKENKQLCTSVYYTIIHN 3672

Query: 160  VDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
             +G G  ++ D ++ D+G Y C A N  G    A   L
Sbjct: 3673 PNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELL 3710



 Score = 47.2 bits (107), Expect = 0.003
 Identities = 32/109 (29%), Positives = 54/109 (49%), Gaps = 15/109 (13%)

Query: 506   PPTKPITHNVTDTS---VTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV- 561
             PP+ P+  +VTD     + ++W    K G S I+GY VE+           P  +  W+ 
Sbjct: 15211 PPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEM----------CPVGTEKWMR 15260

Query: 562   VIARRVHQTHY-VVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
             V +R +    + V + ++P   Y+  VR  N+ G+S PS +S++V   D
Sbjct: 15261 VNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKD 15309



 Score = 47.2 bits (107), Expect = 0.003
 Identities = 45/169 (26%), Positives = 68/169 (40%), Gaps = 18/169 (10%)

Query: 444   RNVTNDGTLVLKDLDKSDSGTYTCVASSRH---GKYVWSGALLVDSPINPNIHFFRAADV 500
             R V  D  +    +D  D+  +  + +S     GKY    +L + +P      F     V
Sbjct: 19568 RKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKY----SLTLVNPAGEKAVFVNVR-V 19622

Query: 501   SSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGW 560
                PGP +     +VT TS  +SW+     G S +  Y VE   RE         + + W
Sbjct: 19623 LDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVE--KREA--------DRKTW 19672

Query: 561   VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
               +   V +T + V +L+PG  Y F V   N +G   P+ V   V   D
Sbjct: 19673 STVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASD 19721



 Score = 47.2 bits (107), Expect = 0.003
 Identities = 61/260 (23%), Positives = 101/260 (38%), Gaps = 36/260 (13%)

Query: 357   TINDTDKNDSRNTIVCSAVNYAG---SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413
             T+    +N   N  +C A+N  G    + + G + V  +   PP I  +    + + +++
Sbjct: 25991 TVTKLKENTEYNFRIC-AINSEGVGEPATLPGSV-VAQERIEPPEIELDADLRKVVVLRA 26048

Query: 414   MAVFPC--TAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVAS 470
              A      T    PEP + W      L    +  VT+  T LV+ ++ + DSG Y     
Sbjct: 26049 SATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLE 26108

Query: 471   SRHG-KYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
             +  G K  +    ++DSP                   P       V   SVTLSW     
Sbjct: 26109 NNSGSKTAFVNVRVLDSP-----------------SAPVNLTIREVKKDSVTLSWEPPLI 26151

Query: 530   IGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRT 589
              G + I  Y VE   RET          + +  I     +T + +++L  G +Y F V  
Sbjct: 26152 DGGAKITNYIVE--KRET--------TRKAYATITNNCTKTTFRIENLQEGCSYYFRVLA 26201

Query: 590   ENSHGLSGPSPVSDSVTVGD 609
              N +G+  P+  ++ V V +
Sbjct: 26202 SNEYGIGLPAETTEPVKVSE 26221



 Score = 47.2 bits (107), Expect = 0.003
 Identities = 38/124 (30%), Positives = 54/124 (43%), Gaps = 7/124 (5%)

Query: 293   PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
             P I        V S +VA+F   ATG P PT  W+ +G + I   G    KY  +    G
Sbjct: 33779 PVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDG-KAITQGG----KYKLSEDKGG 33833

Query: 353   VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
                L I+ TD +DS     C+  N AGS     KLT+ +  D     ++   +++  P K
Sbjct: 33834 F-FLEIHKTDTSDS-GLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQK 33891

Query: 413   SMAV 416
                V
Sbjct: 33892 KAVV 33895



 Score = 46.8 bits (106), Expect = 0.004
 Identities = 45/162 (27%), Positives = 67/162 (41%), Gaps = 14/162 (8%)

Query: 39    PSPAIRWYKGGVLVV---SDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTAR 95
             P P + WYK G  +    +D   +     GL+ L         DA  Y   A N YG   
Sbjct: 32644 PEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDA-EYTVVARNKYGEDS 32702

Query: 96    SR---NATLHV----AVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
              +     TLH     + LR  F+    + +  +G +V  E +   G P P + W+K+GQ 
Sbjct: 32703 CKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFE-IRVSGIPPPTLKWEKDGQP 32761

Query: 149   LLFDGDSRM--HLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
             L    +  +    +D   L I+D    D G Y+  A N AG+
Sbjct: 32762 LSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGS 32803



 Score = 46.8 bits (106), Expect = 0.004
 Identities = 30/103 (29%), Positives = 44/103 (42%), Gaps = 4/103 (3%)

Query: 190   ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249
             +S    +K  +   ++T P  +    G S  F C   G+P+P V W R  G       R 
Sbjct: 33476 KSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRK-GQVLSTSARH 33534

Query: 250   KVLD---DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
             +V       +  + +V  +DEG YS   ENS G   A   LT+
Sbjct: 33535 QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTI 33577



 Score = 46.4 bits (105), Expect = 0.005
 Identities = 54/219 (24%), Positives = 92/219 (42%), Gaps = 12/219 (5%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
           +AP   +    V V     AT      G P P + W++ G ++ + T   +  +      
Sbjct: 4   QAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63

Query: 70  RATHGRV-HSDAGVYWCEATNSYGTARSRNATLHVA-VLREEFRLEPESKQSAQGDTVVL 127
           + T   V  +++G Y  +ATN  G A S    L  A      F    +S    QG  V L
Sbjct: 64  KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRL 123

Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAA 186
           + +   G P P V + ++G  +    D ++    D  +L+I +A   D+G Y   A N+ 
Sbjct: 124 Q-VRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSV 182

Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV 225
           G R ++ A L       L+ G E+V A+   ++    ++
Sbjct: 183 G-RATSTAEL-------LVQGEEEVPAKKTKTIVSTAQI 213



 Score = 46.4 bits (105), Expect = 0.005
 Identities = 36/116 (31%), Positives = 53/116 (45%), Gaps = 13/116 (11%)

Query: 496   RAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPR 555
             +A D   +P  P +PI   VT  S  ++W++ +  G   I  Y +E   RET+S      
Sbjct: 17931 KAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHD-GGKPITNYILE--KRETMS------ 17981

Query: 556   NSRGWVVIARR-VHQ-THYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
               + W  + +  +H  T + V  L+ G  Y F V  EN  G+  PSP S  V   D
Sbjct: 17982 --KRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKD 18035



 Score = 46.4 bits (105), Expect = 0.005
 Identities = 34/110 (30%), Positives = 50/110 (45%), Gaps = 11/110 (10%)

Query: 500   VSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRG 559
             V+ +P PP K    +VT  SV+LSW++    G S I+ Y VE+            ++S  
Sbjct: 24054 VAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEM----------QAKHSEK 24103

Query: 560   WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
             W   A RV     V+ +L  G  Y+F V   N  G S P  ++  +   D
Sbjct: 24104 WSECA-RVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKD 24152



 Score = 46.0 bits (104), Expect = 0.006
 Identities = 32/102 (31%), Positives = 43/102 (42%), Gaps = 3/102 (2%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P ++    +VTV   +  TL C   G PSP + WY+    + S     I    G+  L  
Sbjct: 943  PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 1002

Query: 72   THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE 113
                   D+G + C A N  GT  S +  L V V  EEF  E
Sbjct: 1003 REA-FAEDSGRFTCSAVNEAGTV-STSCYLAVQV-SEEFEKE 1041



 Score = 46.0 bits (104), Expect = 0.006
 Identities = 51/177 (28%), Positives = 77/177 (43%), Gaps = 29/177 (16%)

Query: 425   PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
             PEP I W  EG+ L++  R ++       ++DL + +      V +  HGKY+ S     
Sbjct: 18863 PEPDITWTKEGKVLVREKRVDL-------IQDLPRVELQIKEAVRAD-HGKYIISAK--- 18911

Query: 485   DSPINPNIHFFRAADVSSL--PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEV 542
                 N + H   +A V+ L  PGP       NVT  + T+SW      G S I  + VE 
Sbjct: 18912 ----NSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEY 18967

Query: 543   FSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
                        P N +GW ++A  V +   +  +L+    Y F V  EN  G+ GP+
Sbjct: 18968 ---------RKP-NQKGWSIVASDVTK-RLIKANLLANNEYYFRVCAENKVGV-GPT 19012



 Score = 46.0 bits (104), Expect = 0.006
 Identities = 33/106 (31%), Positives = 48/106 (45%), Gaps = 10/106 (9%)

Query: 506   PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565
             PP KP+  N+T  +VTL W++    G   I  Y VE   R+  +G     N         
Sbjct: 22286 PPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVE--KRDLPNGRWLKAN-------FS 22336

Query: 566   RVHQTHYVVKSLIPGITYMFIVRTENSHG-LSGPSPVSDSVTVGDD 610
              + +  + V  L     Y F V  +N+ G +S PS  SD++T  DD
Sbjct: 22337 NILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDD 22382



 Score = 45.6 bits (103), Expect = 0.008
 Identities = 33/106 (31%), Positives = 43/106 (40%), Gaps = 10/106 (9%)

Query: 504   PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
             P PP      N+T  +  L W+   K G S I  Y VE   R+           +GW  +
Sbjct: 15011 PSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVE--KRDV--------RRKGWQTV 15060

Query: 564   ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
                V  T   V  L  G  Y+F V  EN+ G S  + + DSV   D
Sbjct: 15061 DTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKD 15106



 Score = 45.6 bits (103), Expect = 0.008
 Identities = 63/250 (25%), Positives = 89/250 (35%), Gaps = 40/250 (16%)

Query: 374   AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPS--NQTLPIKS--MAVFPCTAICTPEPII 429
             AVN  G S     L V   DD  PP I    S    T+ +K+      P      P P I
Sbjct: 16298 AVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKI 16357

Query: 430   AWYFEGEALIQN--HRRNVTNDGT--------LVLKDLDKSDSGTYTCVASSRHGKYVWS 479
              W  + E +I+       +T +          L +    + D GTYT  AS+R G     
Sbjct: 16358 EWS-KNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGS---- 16412

Query: 480   GALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQ 539
                     +  N+H     +V   P PP      ++   S  L+W      G S I  Y 
Sbjct: 16413 --------VFRNVH----VEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYV 16460

Query: 540   VEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
             ++          +  R    W  +     +  Y +  LIP   Y F VR  N +G+S   
Sbjct: 16461 IDK--------RDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDEC 16512

Query: 600   PVSDSVTVGD 609
               SD V + D
Sbjct: 16513 K-SDKVVIQD 16521



 Score = 45.6 bits (103), Expect = 0.008
 Identities = 78/327 (23%), Positives = 130/327 (39%), Gaps = 32/327 (9%)

Query: 497   AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556
             A D    PGPP+ P   + T +S++L W    K G S I GY VE+    T         
Sbjct: 16625 AGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEP 16684

Query: 557   SRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD--DSNSL 614
                     + +     VV +L     Y F V+  N  G S PS  +  +   D  +   +
Sbjct: 16685 D-------KLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEV 16737

Query: 615   WEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNI 674
             +   G  +    +       I  +I+  P    T K  WE    +  +        + +I
Sbjct: 16738 FIDIGAQDCLVCKAGSQI-RIPAVIKGRP----TPKSSWE----FDGKAKKAMKDGVHDI 16788

Query: 675   TIEYEMKTILHSNDVSGFEITSLRKYT-KYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDG 733
               + +++T  +S+ +   E    R +T KY    I    K   K +N RV   + DVP G
Sbjct: 16789 PEDAQLETAENSSVIIIPECK--RSHTGKYS---ITAKNKAGQKTANCRV--KVMDVP-G 16840

Query: 734   PPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT 793
             PP ++++  +   +  L W  P+       I GY +    +D    K+   +N     +T
Sbjct: 16841 PPKDLKVSDITRGSCRLSWKMPD-DDGGDRIKGYVIEKRTID---GKAWTKVNPDC-GST 16895

Query: 794   SLIMTNLTSGVSYSVQIAAETIIGLGP 820
             + ++ +L S   Y  ++ AE   G+GP
Sbjct: 16896 TFVVPDLLSEQQYFFRVRAENRFGIGP 16922



 Score = 45.2 bits (102), Expect = 0.011
 Identities = 48/198 (24%), Positives = 82/198 (41%), Gaps = 16/198 (8%)

Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGN--RTIIFPGMSRDKYHATAVF 350
           P+      SV V  G+ A F    +G P P + W  +G    T   PG+        +  
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQ------ISFS 59

Query: 351 DGVTVLTINDTDK-NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409
           DG   LTI    K N  R ++   A N +G +    +L V ++    PP       + T+
Sbjct: 60  DGRAKLTIPAVTKANSGRYSL--KATNGSGQATSTAELLVKAET--APPNFVQRLQSMTV 115

Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYT 466
              S           P P++ +Y +G  +  +    ++ +G   +L++ +    DSGTY+
Sbjct: 116 RQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175

Query: 467 CVASSRHGKYVWSGALLV 484
             A++  G+   +  LLV
Sbjct: 176 VNATNSVGRATSTAELLV 193



 Score = 45.2 bits (102), Expect = 0.011
 Identities = 49/209 (23%), Positives = 81/209 (38%), Gaps = 31/209 (14%)

Query: 300  NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
            ++ ++  G+VA  + T  G P+P + W   G   ++    +  K+    VFDG     I 
Sbjct: 3510 SNADISMGDVATLSVTVIGIPKPKIQWFFNG---VLLTPSADYKF----VFDGDDHSLII 3562

Query: 360  DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTS------DDDRPPPIITN-----GPS--- 405
               K +      C A N  G +     L + S      D +    +  +     GP    
Sbjct: 3563 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 3622

Query: 406  --NQTLPIKSM----AVFPCTAICTPEPIIAWYFEGEALIQNHR----RNVTNDGTLVLK 455
               +  PI+      A+F  T +  P P + W+ E + L  +       N    GT ++ 
Sbjct: 3623 FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 3682

Query: 456  DLDKSDSGTYTCVASSRHGKYVWSGALLV 484
            D  + DSG Y C A +  G+   +  LLV
Sbjct: 3683 DPQREDSGLYICKAENMLGESTCAAELLV 3711



 Score = 45.2 bits (102), Expect = 0.011
 Identities = 36/111 (32%), Positives = 47/111 (42%), Gaps = 4/111 (3%)

Query: 499   DVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558
             D   LPGPP KP     T  S+ +SW+     G S I GY +E   RE        R SR
Sbjct: 16521 DPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLE--KREE-GSPYWSRVSR 16577

Query: 559   GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
                +    +    + V  L+ G+ Y F     N+ G+  PS  SD    GD
Sbjct: 16578 A-PITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGD 16627



 Score = 45.2 bits (102), Expect = 0.011
 Identities = 34/126 (26%), Positives = 55/126 (43%), Gaps = 6/126 (4%)

Query: 205   ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD---GSLRLDN 261
             +T  + +  + G ++    RV G P PD+ W +  G   +   RV ++ D     L++  
Sbjct: 18839 VTCRDVITVRVGQTIRILARVKGRPEPDITWTKE-GKVLVREKRVDLIQDLPRVELQIKE 18897

Query: 262   VILADEGEYSCEAENSVGAVSASGYLTVYDPPS--INLSPNSVNVESGNVARFTCTATGR 319
              + AD G+Y   A+NS G    S  + V D P    NL   +V  E+  ++       G 
Sbjct: 18898 AVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGG 18957

Query: 320   PEPTMF 325
              E T F
Sbjct: 18958 SEITNF 18963



 Score = 45.2 bits (102), Expect = 0.011
 Identities = 36/136 (26%), Positives = 57/136 (41%), Gaps = 6/136 (4%)

Query: 164   NLVIQDARQTDAGRYQCIARNAAGT---RES-AIATLKIHIKPYLITGPEDVVAQTGSSV 219
             +LV+   ++    +++  ARNA G    RE+  +   K  + P  I  PE +  + G  +
Sbjct: 19784 SLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKL 19843

Query: 220   TFQCRVGGDPLPDVLWRRSAGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENS 277
               +  V G P P   W++       +  L   K      L + +V   D G YS  AENS
Sbjct: 19844 RIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENS 19903

Query: 278   VGAVSASGYLTVYDPP 293
              G  +    + V D P
Sbjct: 19904 SGTDTQKIKVVVMDAP 19919



 Score = 45.2 bits (102), Expect = 0.011
 Identities = 32/107 (29%), Positives = 51/107 (47%), Gaps = 12/107 (11%)

Query: 506   PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565
             PP KP   N+T  SVTL W++    G   + GY VE          + P  S+ W+    
Sbjct: 21203 PPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVE--------KRDLP--SKSWMKANH 21252

Query: 566   -RVHQTHYVVKSLIPGITYMFIVRTENSHG-LSGPSPVSDSVTVGDD 610
               V +  + V  L+ G  Y F +R +N+ G +S PS  ++++   D+
Sbjct: 21253 VNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDE 21299



 Score = 45.2 bits (102), Expect = 0.011
 Identities = 30/115 (26%), Positives = 49/115 (42%), Gaps = 12/115 (10%)

Query: 489   NPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETL 548
             +P   F++A D    PGPP  P   + + +S++++W++    G S I GY VE+   E  
Sbjct: 22668 SPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPE-- 22725

Query: 549   SGNNTPRNSRGWVVIA--RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPV 601
                        W ++     +  T Y +  L     Y   +   NS GL  P+ V
Sbjct: 22726 --------EDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALV 22772



 Score = 45.2 bits (102), Expect = 0.011
 Identities = 38/137 (27%), Positives = 60/137 (43%), Gaps = 11/137 (8%)

Query: 174   DAGRYQCIARNAAGT------RESAIATLKIHIKPYLITGPE---DVVAQTGSSVTFQCR 224
             D   ++ IARNA GT          I T   ++ P +  GPE    ++ ++G S+  +  
Sbjct: 28849 DRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKAL 28908

Query: 225   VGGDPLPDVLWRRSAGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVS 282
             V G P+P V W +        M +    VL   SL + +      G Y+ EA+N+ G+  
Sbjct: 28909 VQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAK 28968

Query: 283   ASGYLTVYDPPSINLSP 299
             A   + V D P   + P
Sbjct: 28969 AEIKVKVQDTPGKVVGP 28985



 Score = 44.8 bits (101), Expect = 0.015
 Identities = 30/79 (37%), Positives = 40/79 (50%), Gaps = 7/79 (8%)

Query: 216  GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---RVKVLDDG--SLRLDNVILADEGEY 270
            G  VTF C++ G PLP + W +   G  +  G   ++  L DG  SLR+  V+  DEG Y
Sbjct: 1305 GMGVTFHCKMSGYPLPKIAWYKD--GKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIY 1362

Query: 271  SCEAENSVGAVSASGYLTV 289
            +  A N  G    SG L V
Sbjct: 1363 TAFASNIKGNAICSGKLYV 1381



 Score = 44.8 bits (101), Expect = 0.015
 Identities = 21/54 (38%), Positives = 30/54 (55%)

Query: 489   NPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEV 542
             +P   +++A D    PGPPT     + T  S+TL+W +    G S ILGY VE+
Sbjct: 24832 SPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEI 24885



 Score = 44.8 bits (101), Expect = 0.015
 Identities = 31/99 (31%), Positives = 43/99 (43%), Gaps = 11/99 (11%)

Query: 500   VSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRG 559
             ++  P PP K    +++  SV+L+W +    G S I+ Y VE             +  + 
Sbjct: 27298 ITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALE----------KGQKN 27347

Query: 560   WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
             WV  A     TH+VV  L     Y F V  EN  GLS P
Sbjct: 27348 WVKCA-VAKSTHHVVSGLRENSEYFFRVFAENQAGLSDP 27385



 Score = 44.8 bits (101), Expect = 0.015
 Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 3/80 (3%)

Query: 398   PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVL 454
             P+I  G  + T+   S+A F   A   P P   W  +G+A+ Q  +  ++ D     L +
Sbjct: 33779 PVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEI 33838

Query: 455   KDLDKSDSGTYTCVASSRHG 474
                D SDSG YTC   +  G
Sbjct: 33839 HKTDTSDSGLYTCTVKNSAG 33858



 Score = 44.4 bits (100), Expect = 0.019
 Identities = 32/109 (29%), Positives = 44/109 (40%), Gaps = 10/109 (9%)

Query: 501   SSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGW 560
             +++P PP      + T  S+ L+W      G S I GY VE            PR S  W
Sbjct: 14512 ATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVE----------RCPRGSDKW 14561

Query: 561   VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
             V     V +T   V  L  G  Y + V+  N  G S PS  ++ +   D
Sbjct: 14562 VACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVD 14610



 Score = 44.4 bits (100), Expect = 0.019
 Identities = 29/115 (25%), Positives = 46/115 (40%), Gaps = 10/115 (8%)

Query: 495   FRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTP 554
             F    V   P PP       +T  SV+++W      G S I  Y VE   RE        
Sbjct: 23952 FVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVE--KREA------- 24002

Query: 555   RNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
                + +  +    H+  + +  L  G +Y F V  EN +G+  P+  +D + V +
Sbjct: 24003 -TRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAE 24056



 Score = 44.0 bits (99), Expect = 0.025
 Identities = 36/104 (34%), Positives = 50/104 (48%), Gaps = 13/104 (12%)

Query: 496   RAADVSSLPGPPTKPITH-NVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTP 554
             +A D    PGPP K + H +V  T V+L W++ ++ G S I GY VE +  E        
Sbjct: 18329 KALDPLHPPGPP-KDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVE-YQEE-------- 18378

Query: 555   RNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
               ++ W+   + V     VV  L  G TY F V+ EN  GL  P
Sbjct: 18379 -GTQDWIKF-KTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLP 18420



 Score = 44.0 bits (99), Expect = 0.025
 Identities = 33/112 (29%), Positives = 51/112 (45%), Gaps = 9/112 (8%)

Query: 134   GSPEPNVYWKKNGQTLLFDG-DSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGTRE 190
             G P+P V W + G+ ++ DG   R+    GG   L+I      DA  YQ  A N  G+  
Sbjct: 31880 GHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGS-V 31938

Query: 191   SAIATLKIHIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
             S  A+L++ +      P  + G   V A  G  V+ +    G P P + W++
Sbjct: 31939 SGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQK 31990



 Score = 43.6 bits (98), Expect = 0.034
 Identities = 33/129 (25%), Positives = 58/129 (44%), Gaps = 4/129 (3%)

Query: 110  FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL---VDGGNLV 166
            F  +P  ++  +G +VV  C    G+P+P+VYWKK+G  L      ++          LV
Sbjct: 1084 FITKPVVQKLVEGGSVVFGC-QVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLV 1142

Query: 167  IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVG 226
            I      DAG Y  + RN  G   ++ + L+      L+   ++++ QT  +   Q    
Sbjct: 1143 ISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQTQVTAFVQEPKV 1202

Query: 227  GDPLPDVLW 235
            G+  P  ++
Sbjct: 1203 GETAPGFVY 1211



 Score = 43.6 bits (98), Expect = 0.034
 Identities = 56/215 (26%), Positives = 87/215 (40%), Gaps = 35/215 (16%)

Query: 275  ENSVGAVSASGYLTV--YDPPSINLSPN-----------SVNVESGNVARFTCTATGRPE 321
            E    A++  G +T+  + P  I LSP+           S  V  G+ A F     G+P+
Sbjct: 2047 EEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPD 2106

Query: 322  PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381
            P   W   G +         D+ +     D V  L I D    DS  +I+  A+N AG +
Sbjct: 2107 PECEWYKNGVKI-----ERSDRIYWYWPEDNVCELVIRDVTAEDSA-SIMVKAINIAGET 2160

Query: 382  FVRGKLTVTSDDDRPPPIITNGPSNQTLPIK---SMAVFPCTAICTPEPI--IAWYFEGE 436
                 L V +       +IT     Q +  K   +MA F C    T EP   + WY +G 
Sbjct: 2161 SSHAFLLVQAKQ-----LITFTQELQDVVAKEKDTMATFECE---TSEPFVKVKWYKDGM 2212

Query: 437  ALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCV 468
             + +  +  + +D     L +  +D SD+  Y+CV
Sbjct: 2213 EVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCV 2247



 Score = 43.6 bits (98), Expect = 0.034
 Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 5/93 (5%)

Query: 731   PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH 790
             P  PP  +E+  +   T  LKW+ PE   ++G     N +V   DV   K    ++TTV 
Sbjct: 15010 PPSPPRWLEVINITKNTADLKWTVPE---KDGGSPITNYIVEKRDV-RRKGWQTVDTTV- 15064

Query: 791   QATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQ 823
             + T   +T LT G  Y  ++AAE  IG   +++
Sbjct: 15065 KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTE 15097



 Score = 43.6 bits (98), Expect = 0.034
 Identities = 75/327 (22%), Positives = 123/327 (37%), Gaps = 33/327 (10%)

Query: 302   VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
             +  ++G+        +GRP P + W +E  R         D+   T   D  T LT+ D+
Sbjct: 29584 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRL-----KETDRVSITTTKDRTT-LTVKDS 29637

Query: 362   DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
              + DS    + +  N AG       + V     RP P+   GP    + + S++   C  
Sbjct: 29638 MRGDSGRYFL-TLENTAGVKTFSVTVVVIG---RPGPV--TGP----IEVSSVSAESCV- 29686

Query: 422   ICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS-G 480
             +   EP      E    I   R + T    LV   + ++            +   V S  
Sbjct: 29687 LSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSEN 29746

Query: 481   ALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQV 540
                V  P+           V   P  PT+P  ++V+  ++++ W +    G S I+GY V
Sbjct: 29747 RFGVSKPLESAPIIAEHPFVP--PSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWV 29804

Query: 541   EVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
             E   R T+           WV   +    + +Y V  L+ G+ Y F     N+ G+S  S
Sbjct: 29805 EKKERNTIL----------WVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKAS 29854

Query: 600   PVSDSVTVGD--DSNSLWEGTGVSNST 624
               S  +   +  D+    E T V+ ST
Sbjct: 29855 EASRPIMAQNPVDAPGRPEVTDVTRST 29881



 Score = 43.2 bits (97), Expect = 0.044
 Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 6/97 (6%)

Query: 504   PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
             P PP K     +T  +V LSW      G S +  Y VE      L+ + T      W   
Sbjct: 16939 PDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVEC-----LAWDPTGTKKEAWRQC 16993

Query: 564   ARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
              +R V +  + V+ L+ G  Y F V+  N+ G+S PS
Sbjct: 16994 NKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPS 17030



 Score = 43.2 bits (97), Expect = 0.044
 Identities = 36/113 (31%), Positives = 48/113 (42%), Gaps = 10/113 (8%)

Query: 497   AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556
             A D  + PGPP   +T + T +S  L WS   K G S + GY VE +  E   G      
Sbjct: 17342 ARDPIAPPGPPFPKVT-DWTKSSADLEWSPPLKDGGSKVTGYIVE-YKEE---GKEEWEK 17396

Query: 557   SRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
              +      + V  T  VV  L  G  Y F V   N  G+  P  V+D + + D
Sbjct: 17397 GKD-----KEVRGTKLVVTGLKEGAFYKFRVSAVNIAGIGEPGEVTDVIEMKD 17444



 Score = 43.2 bits (97), Expect = 0.044
 Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 7/102 (6%)

Query: 506   PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565
             PP KP   +VT ++V+L W++    G S I+GY VE      L G+   R +        
Sbjct: 20119 PPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACK---LPGDKWVRCN----TAPH 20171

Query: 566   RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
             ++ Q  Y    L     Y F      +  +S PS  SD VT+
Sbjct: 20172 QIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTI 20213



 Score = 43.2 bits (97), Expect = 0.044
 Identities = 30/101 (29%), Positives = 45/101 (44%), Gaps = 3/101 (2%)

Query: 122   GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQC 180
             GD + +E +P  G P+P V WKK  Q L               ++ I +  ++D+G Y  
Sbjct: 22007 GDNIKVE-IPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPL 22065

Query: 181   IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTF 221
              ARN  G     + T+++H  P   TGP      +   VTF
Sbjct: 22066 TARNIVG-EVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTF 22105



 Score = 43.2 bits (97), Expect = 0.044
 Identities = 48/183 (26%), Positives = 73/183 (39%), Gaps = 29/183 (15%)

Query: 425   PEPIIAWYFEGEALIQNHRRNVTND-GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
             P P   W      L      + T+   TL +++ +++D+G YT    +  G         
Sbjct: 29312 PTPTAVWSKPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSG--------- 29362

Query: 484   VDSPINPNIHFFRAADVSSLPGPPTKPITH-NVTDTSVTLSWSQNNKIGSSSILGYQVEV 542
                  + +I F     V   PGPP  PIT  +VT  S TL W      G + I  Y VE 
Sbjct: 29363 -----SKSITF--TVKVLDTPGPPG-PITFKDVTRGSATLMWDAPLLDGGARIHHYVVE- 29413

Query: 543   FSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602
               RE         + R W VI+ +  +  + V  L  G+ Y F V   N +G+  P  + 
Sbjct: 29414 -KREA--------SRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMP 29464

Query: 603   DSV 605
             + +
Sbjct: 29465 EPI 29467



 Score = 42.7 bits (96), Expect = 0.059
 Identities = 51/178 (28%), Positives = 67/178 (37%), Gaps = 8/178 (4%)

Query: 8    SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGL 66
            S EAP I E+    TV +   A    R  G P P   WYK GV +  SD      P   +
Sbjct: 2074 SMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNV 2133

Query: 67   FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV- 125
              L         D+     +A N  G   S    L  A     F  E +   + + DT+ 
Sbjct: 2134 CEL-VIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMA 2192

Query: 126  VLECLPPRGSPEPNVYWKKNGQTLLFDGDS-RMHLVDGGN-LVIQDARQTDAGRYQCI 181
              EC      P   V W K+G   + +GD  RMH     + L I     +DA  Y C+
Sbjct: 2193 TFEC--ETSEPFVKVKWYKDGME-VHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCV 2247



 Score = 42.7 bits (96), Expect = 0.059
 Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 2/98 (2%)

Query: 211   VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEY 270
             +V + G S        G P P++ W R  G     +   K ++   L +DN    D G+Y
Sbjct: 24961 IVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKY 25020

Query: 271   SCEAENSVGAVSASGYLTVYDPPS--INLSPNSVNVES 306
               + ENS G+ SA   + V D P    NL+   V  +S
Sbjct: 25021 ILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDS 25058



 Score = 42.7 bits (96), Expect = 0.059
 Identities = 36/114 (31%), Positives = 46/114 (40%), Gaps = 15/114 (13%)

Query: 497   AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE---VFSRETLSGNNT 553
             A D  + PG P  P   + T TSV+L+WS     G S + GY +E   V   E    N T
Sbjct: 30953 AMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTT 31012

Query: 554   PRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
             P   R             Y +  L  G  Y F V   N+ G   P+ V  +V V
Sbjct: 31013 PTKIR------------EYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKV 31054



 Score = 42.3 bits (95), Expect = 0.078
 Identities = 32/111 (28%), Positives = 53/111 (47%), Gaps = 7/111 (6%)

Query: 497   AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556
             A D    PGPPT     + T  S+TL W +    G + I+GY VE+  R  ++ + +P  
Sbjct: 19417 AKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEM--RPKIA-DASP-- 19471

Query: 557   SRGW--VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605
               GW     A ++ +  + V SL     Y F V  +N  G+  P+ + +++
Sbjct: 19472 DEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAI 19522



 Score = 42.3 bits (95), Expect = 0.078
 Identities = 34/107 (31%), Positives = 48/107 (44%), Gaps = 12/107 (11%)

Query: 506   PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIA- 564
             PP +P    VT  SVTL W +    G S I GY VE   +E   G         W+  + 
Sbjct: 23368 PPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVE--KKELPEGR--------WMKASF 23417

Query: 565   RRVHQTHYVVKSLIPGITYMFIVRTENSHGL-SGPSPVSDSVTVGDD 610
               +  TH+ V  L+    Y F V   N+ G+ S PS  + ++T  D+
Sbjct: 23418 TNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDE 23464



 Score = 42.3 bits (95), Expect = 0.078
 Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 6/123 (4%)

Query: 692   FEITSLRKYTKYEFFLIPFYKKFEGKPSN-SRVAQTLDDV-PDGPPINIEMFILNTTTVH 749
             +  T L +  +YE  +     +  GKPS  S+    +D + P G P N  +     T+V 
Sbjct: 30918 YRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVS 30977

Query: 750   LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQ 809
             L WS PE +     +TGY + +  +D          NTT  +     +T+L  G  Y  +
Sbjct: 30978 LAWSVPEDE-GGSKVTGYLIEMQKVD---QHEWTKCNTTPTKIREYTLTHLPQGAEYRFR 31033

Query: 810   IAA 812
             + A
Sbjct: 31034 VLA 31036



 Score = 41.9 bits (94), Expect = 0.10
 Identities = 30/107 (28%), Positives = 46/107 (42%), Gaps = 11/107 (10%)

Query: 504   PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
             PG P  P    V+   +T+ W+     G  SI GY +E             ++S  WV +
Sbjct: 19323 PGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLE----------KKEKHSTRWVPV 19372

Query: 564   AR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
              +  + +    V++L+P   Y F V+ EN  G+  PS  S  V   D
Sbjct: 19373 NKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKD 19419



 Score = 41.5 bits (93), Expect = 0.14
 Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 2/69 (2%)

Query: 121  QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQ 179
            +G++V LEC    G P P V W +    +    D ++    G   L+I++A   D+GR+ 
Sbjct: 956  EGESVTLEC-HISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFT 1014

Query: 180  CIARNAAGT 188
            C A N AGT
Sbjct: 1015 CSAVNEAGT 1023



 Score = 41.5 bits (93), Expect = 0.14
 Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 4/86 (4%)

Query: 211   VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL---RLDNVILADE 267
             +  + G++V     V G P+P V W++  G    P   +K+    +L    L +V   D 
Sbjct: 20232 LTVKAGTNVCLDATVFGKPMPTVSWKKD-GTLLKPAEGIKMAMQRNLCTLELFSVNRKDS 20290

Query: 268   GEYSCEAENSVGAVSASGYLTVYDPP 293
             G+Y+  AENS G+ SA+  L V D P
Sbjct: 20291 GDYTITAENSSGSKSATIKLKVLDKP 20316



 Score = 41.5 bits (93), Expect = 0.14
 Identities = 37/132 (28%), Positives = 65/132 (49%), Gaps = 15/132 (11%)

Query: 86    EATNSYGTARSRNATLHVAVLREEFRLEPESK-----QSAQ-GDTVVLECLPPRGSPEPN 139
             +A N  G +  R   L V V+ ++  ++P  K      S Q G+ + +E +P  G P PN
Sbjct: 25213 KAYNEKGKSDPR--VLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIE-IPVIGRPRPN 25269

Query: 140   VYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
             + W K+G+ L     +R+++ +      L I++  + D G+Y   A N+AGT    ++ +
Sbjct: 25270 ISWVKDGEPL--KQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVI 25327

Query: 197   KIHIKPYLITGP 208
              +  KP    GP
Sbjct: 25328 VLE-KPGPPVGP 25338



 Score = 41.5 bits (93), Expect = 0.14
 Identities = 33/108 (30%), Positives = 46/108 (42%), Gaps = 12/108 (11%)

Query: 506   PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV-VIA 564
             PP  P   +VT  ++TL W+   + G S I+GY +E   R+   GN        WV    
Sbjct: 28784 PPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIE--KRQ---GNER------WVRCNF 28832

Query: 565   RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSN 612
               V +  Y V  L PG  Y F +   N+ G   P   S  + +  D N
Sbjct: 28833 TDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDEN 28880



 Score = 41.1 bits (92), Expect = 0.18
 Identities = 30/102 (29%), Positives = 42/102 (41%), Gaps = 8/102 (7%)

Query: 293  PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
            P I L P  V V  G  ARF C  TG P+P + W + G        + R        +DG
Sbjct: 1841 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQ-------LIRKSKRFRVRYDG 1893

Query: 353  VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394
            +  L I D    D+   +  +A N  G    + KL +   +D
Sbjct: 1894 IHYLDIVDCKSYDT-GEVKVTAENPEGVIEHKVKLEIQQRED 1934



 Score = 41.1 bits (92), Expect = 0.18
 Identities = 45/186 (24%), Positives = 71/186 (38%), Gaps = 29/186 (15%)

Query: 425   PEPIIAWYFEGEALIQNHR---RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
             P P   W F  + L    R   + ++    LV+   ++SD G YT    +R         
Sbjct: 14349 PRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENR--------V 14400

Query: 482   LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541
               +   I+ N        V + P  P +    ++T  SV L+W   +  G S + GY VE
Sbjct: 14401 KTISGEIDVN--------VIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVE 14452

Query: 542   VFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPV 601
                RE         + + W  +   V    + V  L+ G  Y+F V   N  G   P+ V
Sbjct: 14453 --KREV--------SRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYV 14502

Query: 602   SDSVTV 607
              + V +
Sbjct: 14503 DEPVNM 14508



 Score = 41.1 bits (92), Expect = 0.18
 Identities = 31/99 (31%), Positives = 45/99 (45%), Gaps = 4/99 (4%)

Query: 214   QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGEYSC 272
             + G S+     + G P P+V W +   G       + V     SL LDNV   D G+Y+ 
Sbjct: 23882 RAGGSLRLFVPIKGRPTPEVKWGK-VDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTL 23940

Query: 273   EAENSVGAVSASGYLTVYDPPS--INLSPNSVNVESGNV 309
               ENS G  SA   + V D PS  +NL    +  +S ++
Sbjct: 23941 TLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSI 23979



 Score = 40.7 bits (91), Expect = 0.24
 Identities = 55/220 (25%), Positives = 72/220 (32%), Gaps = 35/220 (15%)

Query: 202  PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL---DDGSLR 258
            P  I    +     G   T    V G P P + W  + G    P    K +   DD SL 
Sbjct: 3503 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFN-GVLLTPSADYKFVFDGDDHSLI 3561

Query: 259  LDNVILADEGEYSCEAENSVGAVSASGYLTVYD-------------------------PP 293
            +    L DEGEY+C A N  G    S YL +                           PP
Sbjct: 3562 ILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPP 3621

Query: 294  SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
                    +    G  A F  T  G P PT+ W  E  +       +   Y      +G 
Sbjct: 3622 HFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQL-----CTSVYYTIIHNPNGS 3676

Query: 354  TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
                +ND  + DS    +C A N  G S    +L V  +D
Sbjct: 3677 GTFIVNDPQREDS-GLYICKAENMLGESTCAAELLVLLED 3715



 Score = 40.7 bits (91), Expect = 0.24
 Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 2/84 (2%)

Query: 211   VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL-DNVILADEGE 269
             V  + G+S+     V G P P + W +  G        +   +  SL + D V   D G+
Sbjct: 30383 VTIRAGASLRLMVSVSGRPPPVITWSKQ-GIDLASRAIIDTTESYSLLIVDKVNRYDAGK 30441

Query: 270   YSCEAENSVGAVSASGYLTVYDPP 293
             Y+ EAEN  G  SA+  + VYD P
Sbjct: 30442 YTIEAENQSGKKSATVLVKVYDTP 30465



 Score = 40.3 bits (90), Expect = 0.31
 Identities = 25/96 (26%), Positives = 41/96 (42%), Gaps = 2/96 (2%)

Query: 209   EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS--LRLDNVILAD 266
             E +V + G++V F   + G P+P   W                 D+ S  L + N +  D
Sbjct: 18445 EGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRD 18504

Query: 267   EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
              GEY     N+ G+ + + +LTV D P     P ++
Sbjct: 18505 TGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINI 18540



 Score = 40.3 bits (90), Expect = 0.31
 Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 1/56 (1%)

Query: 134   GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGT 188
             G P P   WKK    ++      +H  D  + L+I+D  + D+G Y   A N++GT
Sbjct: 19851 GKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGT 19906



 Score = 40.3 bits (90), Expect = 0.31
 Identities = 33/106 (31%), Positives = 47/106 (44%), Gaps = 10/106 (9%)

Query: 506   PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565
             PP +P   N+T  SV+L WS+ +  G + I GY VE   RE   G     N         
Sbjct: 26614 PPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVE--RRELPDGRWLKCN-------YT 26664

Query: 566   RVHQTHYVVKSLIPGITYMFIVRTEN-SHGLSGPSPVSDSVTVGDD 610
              + +T++ V  L     Y F V   N +  +S PS  +  + V DD
Sbjct: 26665 NIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDD 26710



 Score = 40.3 bits (90), Expect = 0.31
 Identities = 50/190 (26%), Positives = 75/190 (39%), Gaps = 17/190 (8%)

Query: 217   SSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---RVKVLDDG--SLRLDNVILADEGEYS 271
             S+ T  C+V G P P V W R  G   +  G   R++    G   L + +V   D   Y 
Sbjct: 31870 SNATLVCKVTGHPKPIVKWYRQ-GKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQ 31928

Query: 272   CEAENSVGAVSASGYLTVYDPPSINL-----SPNSVNVESGNVARFTCTATGRPEPTMFW 326
               A N  G+VS +  L V  P  I+L        +V+   G V       +G+P+P + W
Sbjct: 31929 VRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITW 31988

Query: 327   SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
               +G   I   G     Y         +++  N  ++ D+   +VC A N  G      +
Sbjct: 31989 Q-KGQDLIDNNG----HYQVIVTRSFTSLVFPNGVERKDAGFYVVC-AKNRFGIDQKTVE 32042

Query: 387   LTVTSDDDRP 396
             L V    D P
Sbjct: 32043 LDVADVPDPP 32052



 Score = 39.9 bits (89), Expect = 0.41
 Identities = 39/141 (27%), Positives = 69/141 (48%), Gaps = 18/141 (12%)

Query: 87    ATNSYGTARSRNATLHVAVLREEFRLEPE-----SKQSAQ-GDTVVLECLPPRGSPEPNV 140
             A N  G  RS   +L V ++ ++  +EP+     S  S Q G  + +E +P  G P+P +
Sbjct: 24132 AVNEKG--RSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIE-VPISGRPKPTI 24188

Query: 141   YWKKNGQTLLFDGDSRMHLVDGGNLV---IQDARQTDAGRYQCIARNAAGTRESAIATLK 197
              W K+G  L     +R+++ D  +L    I++  + D G+Y     N  G + ++I  + 
Sbjct: 24189 TWTKDG--LPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVT 24246

Query: 198   IHIKPYLITGP---EDVVAQT 215
             +  KP    GP   +DV A++
Sbjct: 24247 LD-KPDPPKGPVKFDDVSAES 24266



 Score = 39.5 bits (88), Expect = 0.55
 Identities = 30/83 (36%), Positives = 37/83 (44%), Gaps = 3/83 (3%)

Query: 201  KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLD 260
            KP ++  PE V    G +  F+CRV G P P V W  + G       R +V  DG   LD
Sbjct: 1840 KPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLN-GQLIRKSKRFRVRYDGIHYLD 1898

Query: 261  NVILA--DEGEYSCEAENSVGAV 281
             V     D GE    AEN  G +
Sbjct: 1899 IVDCKSYDTGEVKVTAENPEGVI 1921



 Score = 39.5 bits (88), Expect = 0.55
 Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 4/92 (4%)

Query: 729   DVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTT 788
             D P GPPIN     +  T+V  KW PP L      I  Y +       P ++ +V  +T 
Sbjct: 15727 DTP-GPPINFVFEDIRKTSVLCKWEPP-LDDGGSEIINYTLEKKDKTKPDSEWIVVTSTL 15784

Query: 789   VHQATSLIMTNLTSGVSYSVQIAAETIIGLGP 820
              H   S  +T L  G  Y  ++ AE   G GP
Sbjct: 15785 RHCKYS--VTKLIEGKEYLFRVRAENRFGPGP 15814



 Score = 39.5 bits (88), Expect = 0.55
 Identities = 35/130 (26%), Positives = 58/130 (44%), Gaps = 5/130 (3%)

Query: 695   TSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDV-PDGPPINIEMFILNTTTVHLKWS 753
             T L +  +Y F +       +G+P  S   + +D   P GPP   E+  +   T  + W 
Sbjct: 21461 TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWK 21520

Query: 754   PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAE 813
              P +      ITGY+  V   +  + + + AI T V      + T L  G +Y  +++AE
Sbjct: 21521 RP-VDDGGSEITGYH--VERREKKSLRWVRAIKTPVSDLRCKV-TGLQEGSTYEFRVSAE 21576

Query: 814   TIIGLGPFSQ 823
                G+GP S+
Sbjct: 21577 NRAGIGPPSE 21586



 Score = 39.5 bits (88), Expect = 0.55
 Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 4/99 (4%)

Query: 211   VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGE 269
             VV +  +++     + G P P+V W + A G      +++V    + L +DNV   D G 
Sbjct: 26044 VVLRASATLRLFVTIKGRPEPEVKWEK-AEGILTDRAQIEVTSSFTMLVIDNVTRFDSGR 26102

Query: 270   YSCEAENSVGAVSASGYLTVYDPPS--INLSPNSVNVES 306
             Y+   EN+ G+ +A   + V D PS  +NL+   V  +S
Sbjct: 26103 YNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDS 26141



 Score = 39.5 bits (88), Expect = 0.55
 Identities = 35/131 (26%), Positives = 57/131 (43%), Gaps = 5/131 (3%)

Query: 690   SGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVP-DGPPINIEMFILNTTTV 748
             S F+ T L +  +Y F +    +   G    S V +    +   GPP  +++F ++   +
Sbjct: 30816 STFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGM 30875

Query: 749   HLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSV 808
              L W PPE       +TGY  +V   +V A++  V +N      T    T LT G+ Y  
Sbjct: 30876 TLTWYPPE-DDGGSQVTGY--IVERKEVRADR-WVRVNKVPVTMTRYRSTGLTEGLEYEH 30931

Query: 809   QIAAETIIGLG 819
             ++ A    G G
Sbjct: 30932 RVTAINARGSG 30942



 Score = 39.1 bits (87), Expect = 0.72
 Identities = 53/234 (22%), Positives = 86/234 (36%), Gaps = 39/234 (16%)

Query: 292  PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW-----SVEGN------------RTI 334
            PP++     +V V  G      C  +G P PT+ W      +E +            R +
Sbjct: 942  PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 1001

Query: 335  IFPGMSRD--KYHATAVFDGVTV-----LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387
            I    + D  ++  +AV +  TV     L +  +++ +   T V          FV  + 
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRD 1061

Query: 388  TVTSDD----------DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437
             V +D           +   P     P  Q L      VF C     P+P + W   G  
Sbjct: 1062 VVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVP 1121

Query: 438  LIQNHRRNV-----TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
            L   +R  V     T +  LV+      D+G YT V  ++HG+   S +LL ++
Sbjct: 1122 LTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEA 1175



 Score = 39.1 bits (87), Expect = 0.72
 Identities = 41/198 (20%), Positives = 81/198 (40%), Gaps = 12/198 (6%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-THRSILPAGGLFFLR 70
            P  + +P+       Q A  + +  G P P   W+  G  +V+D TH+ ++   G   L 
Sbjct: 1457 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1516

Query: 71   ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR---LEPESKQSAQGDTVVL 127
                   SD+G +   A N  G + S +  L V  +  + +   +E     + +  + + 
Sbjct: 1517 IVPA-TPSDSGEWTVVAQNRAGRS-SISVILTVEAVEHQVKPMFVEKLKNVNIKEGSQLE 1574

Query: 128  ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG----GNLVIQDARQTDAGRYQCIAR 183
              +   G+P P++ W KN   ++     ++  ++G      L I      D+  Y   A 
Sbjct: 1575 MKVRATGNPNPDIVWLKNSDIIVPHKYPKIR-IEGTKGEAALKIDSTVSQDSAWYTATAI 1633

Query: 184  NAAGTRESAIATLKIHIK 201
            N AG R++    + + ++
Sbjct: 1634 NKAG-RDTTRCKVNVEVE 1650



 Score = 39.1 bits (87), Expect = 0.72
 Identities = 32/112 (28%), Positives = 55/112 (49%), Gaps = 11/112 (9%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAG--GSPSPAIRW-YKGGVLVVSDTHRSILPAGGL 66
            + P+  ++   + + R  PA   CR    G P+  + W + G  L  ++  R I   G  
Sbjct: 1701 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFG-- 1758

Query: 67   FFLRATHGRVHS-DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK 117
             +    +G  +S D+G+  C ATN YGT  + +ATL   ++++E  L  ES+
Sbjct: 1759 -YCSLDYGVAYSRDSGIITCRATNKYGTDHT-SATL---IVKDEKSLVEESQ 1805



 Score = 39.1 bits (87), Expect = 0.72
 Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 5/84 (5%)

Query: 122   GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL---VDGGNLVIQDARQTDAGRY 178
             GDT+ LE    RG P P V W K+          R+ +    D     +  A+++D G+Y
Sbjct: 19143 GDTIRLEA-GVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKY 19201

Query: 179   QCIARNAAGTRESAIATLKIHIKP 202
                A N AG+   A AT+ +  KP
Sbjct: 19202 VVTATNTAGS-FVAYATVNVLDKP 19224



 Score = 39.1 bits (87), Expect = 0.72
 Identities = 37/132 (28%), Positives = 59/132 (44%), Gaps = 11/132 (8%)

Query: 692   FEITSLRKYTKYEFFLIPF--YKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVH 749
             F +T L +  +Y F +     Y   EG  S   VA+   DVPD PP    +  +   +V 
Sbjct: 21062 FRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPP-NIVDVRHDSVS 21120

Query: 750   LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMV--AINTTVHQATSLIMTNLTSGVSYS 807
             L W+ P+ +     ITGY+     L+     S++    N T  +     +T LT G+ Y 
Sbjct: 21121 LTWTDPK-KTGGSPITGYH-----LEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYE 21174

Query: 808   VQIAAETIIGLG 819
              ++ A  + G+G
Sbjct: 21175 FRVMAINLAGVG 21186



 Score = 39.1 bits (87), Expect = 0.72
 Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 8/105 (7%)

Query: 499   DVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558
             D +  PGPP+ P   + T  S +L+W + +  G   I GY VE    + +      +++ 
Sbjct: 21595 DAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVE---HQKVGDEAWIKDTT 21651

Query: 559   GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
             G    A R+  T +VV  L     Y F +   N  G+  P+ + D
Sbjct: 21652 G---TALRI--TQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPD 21691



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 69/306 (22%), Positives = 114/306 (37%), Gaps = 19/306 (6%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            EA  I +   ++TV   Q A             ++W K GV++ S+   +I   G ++ L
Sbjct: 2705 EAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSL 2764

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
            R  +  +  D  VY         +AR     LHV  ++     +P+   + +  TV  E 
Sbjct: 2765 RIKNCAI-VDESVYGFRLGRLGASAR-----LHVETVK--IIKKPKDVTALENATVAFE- 2815

Query: 130  LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
            +       P  ++ KN +    D    +       L++Q+   +DAG Y  +        
Sbjct: 2816 VSVSHDTVPVKWFHKNVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAVVGQLECKA 2875

Query: 190  ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249
            +  + TL I      I  PE   A      +F+C V    +P  +W ++     M   + 
Sbjct: 2876 KLFVETLHITKTMKNIEVPETKTA------SFECEVSHFNVPS-MWLKNGVEIEMS-EKF 2927

Query: 250  KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309
            K++  G L    +I+    E S E     G    S  LTV  P  I      +N E  + 
Sbjct: 2928 KIVVQGKLH-QLIIMNTSTEDSAEYTFVCGNDQVSATLTV-TPIMITSMLKDINAEEKDT 2985

Query: 310  ARFTCT 315
              F  T
Sbjct: 2986 ITFEVT 2991



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 25/89 (28%), Positives = 43/89 (48%), Gaps = 6/89 (6%)

Query: 731   PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH 790
             P GPP ++    ++ T V L W+ P+       ITGY  +V + +    +  +   T  +
Sbjct: 18336 PPGPPKDLHHVDVDKTEVSLVWNKPDRD-GGSPITGY--LVEYQE-EGTQDWIKFKTVTN 18391

Query: 791   QATSLIMTNLTSGVSYSVQIAAETIIGLG 819
                  ++T L  G +Y  ++ AE I+GLG
Sbjct: 18392 --LECVVTGLQQGKTYRFRVKAENIVGLG 18418



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 29/112 (25%), Positives = 49/112 (43%), Gaps = 9/112 (8%)

Query: 87    ATNSYGTARSRNATLHVAVLREEFR-----LEPESKQSAQ---GDTVVLECLPPRGSPEP 138
             A N+ G   + + +    + ++E+      L+P  K       GDT+VL  +   G P P
Sbjct: 21277 AKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLP 21336

Query: 139   NVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTR 189
                W K G+ +     +++      + L I+ A + DAG Y   A N  GT+
Sbjct: 21337 KSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTK 21388



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 48/186 (25%), Positives = 75/186 (40%), Gaps = 17/186 (9%)

Query: 41    PAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV--HSDAGVYWCEATNSYGTARSRN 98
             P  RW K     + DTH  +    GL        RV   + AGV+  E + S G   +R+
Sbjct: 23408 PEGRWMKASFTNIIDTHFEVT---GLVEDHRYEFRVIARNAAGVF-SEPSESTGAITARD 23463

Query: 99    ATLHVAVLREEFRLEPESKQSA---QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155
                   V      ++P+ K +     G++  ++     G P P + W K  Q L      
Sbjct: 23464 E-----VDPPRISMDPKYKDTIVVHAGESFKVDA-DIYGKPIPTIQWIKGDQELSNTARL 23517

Query: 156   RMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQ 214
              +   D   +L ++DA + D+G Y   A+N AG R S    +K+  +P    GP  +   
Sbjct: 23518 EIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGER-SVTVNVKVLDRPGPPEGPVVISGV 23576

Query: 215   TGSSVT 220
             T    T
Sbjct: 23577 TAEKCT 23582



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 32/107 (29%), Positives = 47/107 (43%), Gaps = 12/107 (11%)

Query: 506   PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIA- 564
             PP +P    +T  +VTL W +    G S I GY VE   ++   G         W+  + 
Sbjct: 25532 PPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVE--KKDLPDGR--------WMKASF 25581

Query: 565   RRVHQTHYVVKSLIPGITYMFIVRTENSHG-LSGPSPVSDSVTVGDD 610
               V +T + V  L+    Y F V   N+ G  S PS  S ++T  D+
Sbjct: 25582 TNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDE 25628



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 29/98 (29%), Positives = 48/98 (48%), Gaps = 6/98 (6%)

Query: 134   GSPEPNVYWKKNGQTLLFDGDSRM-HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
             G P P + W K+ + L  +    + +  D  +++I+DA + ++G Y+   RNA G   SA
Sbjct: 27825 GKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMG---SA 27881

Query: 193   IATLKIHI--KPYLITGPEDVVAQTGSSVTFQCRVGGD 228
              AT+++ I  KP    GP +    T   +T   R   D
Sbjct: 27882 SATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPAD 27919



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 31/117 (26%), Positives = 47/117 (40%), Gaps = 11/117 (9%)

Query: 497   AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556
             A D  + PGPP      +VT   V L W      G   I  Y +E   +E L        
Sbjct: 15104 AKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIE--KKERLGTR----- 15156

Query: 557   SRGWVVIARRV-HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSN 612
                WV   +      ++ V  +I G    F VR EN  G+  PS  ++ +++ D ++
Sbjct: 15157 ---WVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTS 15210



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 11/113 (9%)

Query: 497   AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556
             A D  S PGPP   +T + + T++ L W      G   I+GY V+   ++ +  N   R 
Sbjct: 15923 AHDPISPPGPPIPRVT-DTSSTTIELEWEPPAFNGGGEIVGYFVD---KQLVGTNEWSRC 15978

Query: 557   SRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
             +   +    +V Q  Y VK +  G  Y   V   N+ G  GP   +  VTV +
Sbjct: 15979 TEKMI----KVRQ--YTVKEIREGADYKLRVSAVNAAG-EGPPGETQPVTVAE 16024



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 27/92 (29%), Positives = 45/92 (48%), Gaps = 5/92 (5%)

Query: 729   DVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTT 788
             D+P  P   I+   +++  V   W PPE    +G +   N VV      +  + V + TT
Sbjct: 22084 DIPGPPTGPIKFDEVSSDFVTFSWDPPE---NDGGVPISNYVVEMRQTDST-TWVELATT 22139

Query: 789   VHQATSLIMTNLTSGVSYSVQIAAETIIGLGP 820
             V + T+   T LT+G+ Y  ++ A+   G+GP
Sbjct: 22140 VIR-TTYKATRLTTGLEYQFRVKAQNRYGVGP 22170



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 6/91 (6%)

Query: 729   DVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTT 788
             D P  PP+N+++  +   +V + W PP   L +G     N +V   +    KS  A+ T 
Sbjct: 23959 DTPS-PPVNLKVTEITKDSVSITWEPP---LLDGGSKIKNYIVEKREA-TRKSYAAVVTN 24013

Query: 789   VHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819
              H+  S  +  L  G SY  ++ AE   G+G
Sbjct: 24014 CHK-NSWKIDQLQEGCSYYFRVTAENEYGIG 24043



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 6/81 (7%)

Query: 134   GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIARNAAGTRE 190
             G P P + W K+G  +  +  +R  ++   N   L ++D  + D G+Y    +N AGTR 
Sbjct: 26742 GRPLPVISWAKDG--IEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRS 26799

Query: 191   SAIATLKIHIKPYLITGPEDV 211
              A+   K+  KP    GP ++
Sbjct: 26800 VAV-NCKVLDKPGPPAGPLEI 26819



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 1/70 (1%)

Query: 130   LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGT 188
             +P +G P P V W+K+ + L  D    +   D  +L+ I    + D G+Y     N  G 
Sbjct: 28220 IPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGE 28279

Query: 189   RESAIATLKI 198
              +S+  ++K+
Sbjct: 28280 PKSSTVSVKV 28289



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 28/102 (27%), Positives = 51/102 (50%), Gaps = 7/102 (6%)

Query: 122   GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD---GGNLVIQDARQTDAGRY 178
             G+++ ++ L  +G P P V W K+G  +  +    M + D     +L ++DA +   G Y
Sbjct: 28900 GESLRIKALV-QGRPVPRVTWFKDGVEI--EKRMNMEITDVLGSTSLFVRDATRDHRGVY 28956

Query: 179   QCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVT 220
                A+NA+G+ ++ I  +K+   P  + GP      TG  +T
Sbjct: 28957 TVEAKNASGSAKAEI-KVKVQDTPGKVVGPIRFTNITGEKMT 28997



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 77/332 (23%), Positives = 130/332 (39%), Gaps = 52/332 (15%)

Query: 291   DPPSINLSPN---SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
             +PP++ L  +    + + +G   R     TGRP PT  W+ E         + +D+    
Sbjct: 16027 EPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGE------LDKDR---- 16076

Query: 348   AVFDGV---TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404
              V D V   + L I D  + D     V +A N  GS F   ++ V    D P P++   P
Sbjct: 16077 VVIDNVGTKSELIIKDALRKD-HGRYVITATNSCGSKFAAARVEVF---DVPGPVLDLKP 16132

Query: 405   --SNQTLPIKSMAVFPCTAICTPEPIIAWYFE-GEALIQNHRRNV-TNDGTLVLKDLDKS 460
               +N+ + + + +            I  +  E  +A +   R+ + T      +  L + 
Sbjct: 16133 VVTNRKMCLLNWSDPEDDG---GSEITGFIIERKDAKMHTWRQPIETERSKCDITGLLEG 16189

Query: 461   DSGTYTCVASSRH--GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDT 518
                 +  +A ++   G  V  G +L   P+ P             P  P +      T +
Sbjct: 16190 QEYKFRVIAKNKFGCGPPVEIGPILAVDPLGP-------------PTSPERLTYTERTKS 16236

Query: 519   SVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLI 578
             ++TL W +    G S I GY +E   R     ++ P   R   V  R    T ++V++L 
Sbjct: 16237 TITLDWKEPRSNGGSPIQGYIIE--KRR----HDKPDFER---VNKRLCPTTSFLVENLD 16287

Query: 579   PGITYMFIVRTENSHGLSGPSPVSDSVTVGDD 610
                 Y F V+  N  G S PS +  +V + DD
Sbjct: 16288 EHQMYEFRVKAVNEIGESEPS-LPLNVVIQDD 16318



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 25/100 (25%), Positives = 42/100 (42%), Gaps = 4/100 (4%)

Query: 211   VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKV---LDDGSLRLDNVILAD 266
             +  + G ++  +  V G P P+V W +     ++    RVK+    D     L     +D
Sbjct: 19138 LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSD 19197

Query: 267   EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
              G+Y   A N+ G+  A   + V D P    +   V+V S
Sbjct: 19198 GGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSS 19237



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 40/185 (21%), Positives = 70/185 (37%), Gaps = 22/185 (11%)

Query: 425   PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
             P P + W        +   +N+ +D    +++ D S   T   V  +  GKY+ +    V
Sbjct: 28226 PPPTVTW--------RKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGV 28277

Query: 485   DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFS 544
               P +  +    +  V   P    K    +V+  +VTL W      G S I+ Y +E   
Sbjct: 28278 GEPKSSTV----SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIE--K 28331

Query: 545   RETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDS 604
             R+           R W V++ +   T + +  L     + F V  EN  G+  P   ++ 
Sbjct: 28332 RDA--------TKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEP 28383

Query: 605   VTVGD 609
             V   +
Sbjct: 28384 VKAAE 28388



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 31/120 (25%), Positives = 51/120 (42%), Gaps = 12/120 (10%)

Query: 504   PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
             P PP +    + + +S  L+W + +  G S I GY +E+            + S  WV  
Sbjct: 29473 PAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEM----------RQKGSDFWVE- 29521

Query: 564   ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDS-NSLWEGTGVSN 622
             A    Q  + V+ L+    Y F V+ +N  G S P     SV + +       + TG++N
Sbjct: 29522 AGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITN 29581



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 38/153 (24%), Positives = 64/153 (41%), Gaps = 9/153 (5%)

Query: 44    RWYKGGVLVVSDTHRSI--LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATL 101
             RW K    +VSD   ++  L  G  +  R       + AGV   + + S G    R+   
Sbjct: 29914 RWLKCNYTIVSDNFFTVTALSEGDTYEFRVL---AKNAAGVI-SKGSESTGPVTCRDEYA 29969

Query: 102   HVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLV 160
                    + RL  +      G  +VL+     G PEP + W K  + L L +  S  +  
Sbjct: 29970 PPKA-ELDARLHGDLVTIRAGSDLVLDAAVG-GKPEPKIIWTKGDKELDLCEKVSLQYTG 30027

Query: 161   DGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
                  VI+   ++D+G+Y    +NA+GT+  ++
Sbjct: 30028 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSV 30060



 Score = 37.5 bits (83), Expect = 2.2
 Identities = 28/117 (23%), Positives = 50/117 (42%), Gaps = 10/117 (8%)

Query: 200   IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---- 255
             IK  L    + +  + G  V     V G P+P + W ++      P   +++  +     
Sbjct: 16324 IKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRS 16383

Query: 256   ----SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS--INLSPNSVNVES 306
                  L +   +  D+G Y+  A N +G+V  + ++ VYD PS   NL+   +  ES
Sbjct: 16384 EAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAES 16440



 Score = 37.5 bits (83), Expect = 2.2
 Identities = 35/127 (27%), Positives = 51/127 (40%), Gaps = 5/127 (3%)

Query: 692   FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751
             F+ T L +  +YEF +        GKPS         D P  PP   E  I+   +V L+
Sbjct: 23327 FKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARD-PCDPPGRPEAIIVTRNSVTLQ 23385

Query: 752   WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811
             W  P        ITGY  +V   ++P  + M A  T +   T   +T L     Y  ++ 
Sbjct: 23386 WKKPTYD-GGSKITGY--IVEKKELPEGRWMKASFTNIID-THFEVTGLVEDHRYEFRVI 23441

Query: 812   AETIIGL 818
             A    G+
Sbjct: 23442 ARNAAGV 23448



 Score = 37.5 bits (83), Expect = 2.2
 Identities = 32/105 (30%), Positives = 45/105 (42%), Gaps = 10/105 (9%)

Query: 506   PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565
             PP      +++  SV+LSW Q    G S I GY VE   R+   G  T  +         
Sbjct: 27697 PPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVE--RRDLPDGRWTKAS-------FT 27747

Query: 566   RVHQTHYVVKSLIPGITYMFIVRTENSHG-LSGPSPVSDSVTVGD 609
              V +T +++  L     Y F V   N+ G +S PS V   +T  D
Sbjct: 27748 NVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCID 27792



 Score = 37.5 bits (83), Expect = 2.2
 Identities = 30/106 (28%), Positives = 45/106 (42%), Gaps = 9/106 (8%)

Query: 504   PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
             PGPPT     + + T+V+L WS+    G   I+GY +E+   +   G+    N+   V  
Sbjct: 29181 PGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADL--GDWHKVNAEACV-- 29236

Query: 564   ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
                  +T Y V  L  G  Y F V   N  G      V+ ++   D
Sbjct: 29237 -----KTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVD 29277



 Score = 37.5 bits (83), Expect = 2.2
 Identities = 22/79 (27%), Positives = 32/79 (40%), Gaps = 3/79 (3%)

Query: 400   ITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN---DGTLVLKD 456
             I   P + T+     A F C     P P + W  +G+ L  + R  VT      T  +  
Sbjct: 33490 ILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISS 33549

Query: 457   LDKSDSGTYTCVASSRHGK 475
             +  SD G Y+ V  +  GK
Sbjct: 33550 VQASDEGNYSVVVENSEGK 33568



 Score = 37.1 bits (82), Expect = 2.9
 Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 2/89 (2%)

Query: 133   RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRES 191
             RG P P   W  +G  +  D    +   +  + L I++  + D G YQ    NAAG++  
Sbjct: 18462 RGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTV 18521

Query: 192   AIATLKIHIKPYLITGPEDVVAQTGSSVT 220
             A+    + + P   TGP +++  T   +T
Sbjct: 18522 AVHLTVLDV-PGPPTGPINILDVTPEHMT 18549



 Score = 37.1 bits (82), Expect = 2.9
 Identities = 30/110 (27%), Positives = 41/110 (37%), Gaps = 11/110 (10%)

Query: 500   VSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRG 559
             VS  P PP +    +VT  + T+ W +    G S I GY VE+            + S  
Sbjct: 26219 VSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEM----------QTKGSEK 26268

Query: 560   WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
             W     +V      +  L  G  Y+F V   N  G S P  +   V   D
Sbjct: 26269 WST-CTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARD 26317



 Score = 36.7 bits (81), Expect = 3.9
 Identities = 16/52 (30%), Positives = 26/52 (50%), Gaps = 2/52 (3%)

Query: 1    MSDDYVTSGE--APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV 50
            ++++    GE  APY I +P+   +         C+ GG+P P + W K GV
Sbjct: 1069 LTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1120



 Score = 36.7 bits (81), Expect = 3.9
 Identities = 37/124 (29%), Positives = 53/124 (42%), Gaps = 10/124 (8%)

Query: 110  FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVI 167
            F  E  +   + GD   L  +   G P+P + W  NG  L    D +  + DG +  L+I
Sbjct: 3505 FIKEVSNADISMGDVATLS-VTVIGIPKPKIQWFFNGVLLTPSADYKF-VFDGDDHSLII 3562

Query: 168  QDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGG 227
               +  D G Y C+A N  G +    A LKI+ K     G +D   +T S+V       G
Sbjct: 3563 LFTKLEDEGEYTCMASNDYG-KTICSAYLKINSKG---EGHKD--TETESAVAKSLEKLG 3616

Query: 228  DPLP 231
             P P
Sbjct: 3617 GPCP 3620



 Score = 36.7 bits (81), Expect = 3.9
 Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 2/83 (2%)

Query: 134   GSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
             G P P + W K+G+ L       + + D   NLV +D+ + D+G Y   A N  G  +  
Sbjct: 22414 GRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKH- 22472

Query: 193   IATLKIHIKPYLITGPEDVVAQT 215
             I  +K+  +P    GP  V   T
Sbjct: 22473 IFNVKVLDRPGPPEGPLAVTEVT 22495



 Score = 36.7 bits (81), Expect = 3.9
 Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 9/103 (8%)

Query: 719   SNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPA 778
             S   VAQ    VP GPP    + + +  ++ ++W+ P   + +G   G  V+   L+   
Sbjct: 23256 SEPTVAQYPFKVP-GPPGTPVVTLSSRDSMEVQWNEP---ISDG---GSRVIGYHLERKE 23308

Query: 779   NKSM--VAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819
               S+  V +N T    T    T L  GV Y  +++AE I+G+G
Sbjct: 23309 RNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIG 23351



 Score = 36.7 bits (81), Expect = 3.9
 Identities = 20/62 (32%), Positives = 36/62 (58%), Gaps = 5/62 (8%)

Query: 130   LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCIARNAA 186
             +P +G P+  V W+K+GQTL     +R+++       +L I++A + D G Y+    N+A
Sbjct: 26343 VPFKGRPQATVNWRKDGQTL--KETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSA 26400

Query: 187   GT 188
             G+
Sbjct: 26401 GS 26402



 Score = 36.7 bits (81), Expect = 3.9
 Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 6/123 (4%)

Query: 702   KYEFFLIPFYKKFEGKPSNSR--VAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQL 759
             +Y+F +    K   G+P +S   VAQ    VPD P I  E   +   ++ L W+ PE   
Sbjct: 29048 EYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIP-EPSNITGNSITLTWARPE--- 29103

Query: 760   QNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819
              +G       ++   +  + + +  I+      T   +T LT G  Y   + AE   G+G
Sbjct: 29104 SDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVG 29163

Query: 820   PFS 822
             P S
Sbjct: 29164 PAS 29166



 Score = 36.3 bits (80), Expect = 5.1
 Identities = 34/126 (26%), Positives = 51/126 (40%), Gaps = 10/126 (7%)

Query: 177   RYQCIARNAAGTRESAIATLKIHIK-----PYLITGPEDVVAQ---TGSSVTFQCRVGGD 228
             +++ +A NAAG  + A     + +K     P LI        Q    G ++     + G 
Sbjct: 18113 KFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGV 18172

Query: 229   PLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYL 287
             P P V W++          R+ V   GS L + N    D G YS   EN  G+ + S  +
Sbjct: 18173 PFPKVTWKKEDRDAPTK-ARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKV 18231

Query: 288   TVYDPP 293
              V D P
Sbjct: 18232 LVLDKP 18237



 Score = 36.3 bits (80), Expect = 5.1
 Identities = 28/89 (31%), Positives = 42/89 (47%), Gaps = 5/89 (5%)

Query: 733   GPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQA 792
             GPP ++E+  +   + +L W  P L     +IT Y  VV   DV A+     ++ T  + 
Sbjct: 18238 GPPRDLEVSEIRKDSCYLTWKEP-LDDGGSVITNY--VVERRDV-ASAQWSPLSAT-SKK 18292

Query: 793   TSLIMTNLTSGVSYSVQIAAETIIGLGPF 821
              S    +L  G  Y  ++AAE   G GPF
Sbjct: 18293 KSHFAKHLNEGNQYLFRVAAENQYGRGPF 18321



 Score = 36.3 bits (80), Expect = 5.1
 Identities = 22/68 (32%), Positives = 39/68 (57%), Gaps = 6/68 (8%)

Query: 133   RGSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCIARNAAG-T 188
             +G PEP++ W K G+ L+   + R+ L+       L I++A + D G+Y   A+N++G  
Sbjct: 18860 KGRPEPDITWTKEGKVLV--REKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHA 18917

Query: 189   RESAIATL 196
             + SAI  +
Sbjct: 18918 QGSAIVNV 18925



 Score = 36.3 bits (80), Expect = 5.1
 Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 6/91 (6%)

Query: 729   DVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTT 788
             D P GPP ++++  +  T+V L W PP   L +G     N +V   +    K+   + T 
Sbjct: 22877 DTP-GPPQDLKVKEVTKTSVTLTWDPP---LLDGGSKIKNYIVEKRE-STRKAYSTVATN 22931

Query: 789   VHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819
              H+ TS  +  L  G SY  ++ AE   G+G
Sbjct: 22932 CHK-TSWKVDQLQEGCSYYFRVLAENEYGIG 22961



 Score = 36.3 bits (80), Expect = 5.1
 Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 4/99 (4%)

Query: 211   VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGE 269
             ++ + G+S T      G P+P+VLW +           V   D   SL ++N    D G+
Sbjct: 27123 LIVKAGASFTMTVPFRGRPVPNVLWSK-PDTDLRTRAYVDTTDSRTSLTIENANRNDSGK 27181

Query: 270   YSCEAENSVGAVSASGYLTVYDPPS--INLSPNSVNVES 306
             Y+   +N + A S +  + V D P    N++   V  ES
Sbjct: 27182 YTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKES 27220



 Score = 36.3 bits (80), Expect = 5.1
 Identities = 27/98 (27%), Positives = 42/98 (42%), Gaps = 4/98 (4%)

Query: 27    QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
             Q      R  G P P ++W K G  +    +  I+  G  ++       +  D G Y   
Sbjct: 32737 QSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVT 32796

Query: 87    ATNSYGTARSRNATLHVAVLR---EEFRLEPESKQSAQ 121
             ATN+ G+  S  A L V  LR   +EF+ + E ++  Q
Sbjct: 32797 ATNTAGST-SCQAHLQVERLRYKKQEFKSKEEHERHVQ 32833



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 4/102 (3%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            + P I+  P  V V   + A   CR  G P P + WY  G L +  + R  +   G+ +L
Sbjct: 1839 QKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQL-IRKSKRFRVRYDGIHYL 1897

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR 111
                 + + D G     A N  G    +   L +   RE+FR
Sbjct: 1898 DIVDCKSY-DTGEVKVTAENPEGVIEHK-VKLEIQ-QREDFR 1936



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 24/82 (29%), Positives = 33/82 (40%), Gaps = 1/82 (1%)

Query: 112  LEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR 171
            L PE  +  +G+T    C    G P+P V W  NGQ +      R+       L I D +
Sbjct: 1845 LYPEPVRVLEGETARFRCRVT-GYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCK 1903

Query: 172  QTDAGRYQCIARNAAGTRESAI 193
              D G  +  A N  G  E  +
Sbjct: 1904 SYDTGEVKVTAENPEGVIEHKV 1925



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 33/132 (25%), Positives = 57/132 (43%), Gaps = 8/132 (6%)

Query: 690   SGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDV---PDGPPINIEMFILNTT 746
             + F +T+L    +Y F +    +   G P++        D    PD PP  +E+  +   
Sbjct: 19682 TSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPD-PPRKLEVTEMTKN 19740

Query: 747   TVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSY 806
             +  L W PP L+     I GY       + PA++       +V +  SL++T L  G  Y
Sbjct: 19741 SATLAWLPP-LRDGGAKIDGYITSYREEEQPADRWT---EYSVVKDLSLVVTGLKEGKKY 19796

Query: 807   SVQIAAETIIGL 818
               ++AA   +G+
Sbjct: 19797 KFRVAARNAVGV 19808



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 23/82 (28%), Positives = 33/82 (40%), Gaps = 1/82 (1%)

Query: 12    PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
             P  I  P  +T+   +   +     G P P  +W KG   VV+ +H ++  A     L  
Sbjct: 19826 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSIL-I 19884

Query: 72    THGRVHSDAGVYWCEATNSYGT 93
                    D+G Y   A NS GT
Sbjct: 19885 IKDVTRKDSGYYSLTAENSSGT 19906



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 6/94 (6%)

Query: 130   LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGT 188
             +P  G P P V W K+   L           +  +L+ I+DA + D G Y     N+AG 
Sbjct: 23096 VPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAG- 23154

Query: 189   RESAIATLKIHI--KPYLITGPEDVVAQTGSSVT 220
                AI TL + +  KP   TGP  +   T  S+T
Sbjct: 23155 --EAIETLNVIVLDKPGPPTGPVKMDEVTADSIT 23186



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 35/144 (24%), Positives = 51/144 (35%), Gaps = 10/144 (6%)

Query: 166   VIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED--------VVAQTGS 217
             V+   R+     ++  A N AG  +     L + IK  L     D        V  + GS
Sbjct: 27360 VVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGS 27419

Query: 218   SVTFQCRVGGDPLPDVLWRRSAGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAE 275
             ++     + G PLP V   R        M        ++ ++ L   + AD G Y   A 
Sbjct: 27420 NLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAA 27479

Query: 276   NSVGAVSASGYLTVYDPPSINLSP 299
             NS G   A   + V D P     P
Sbjct: 27480 NSSGTTKAFINIVVLDRPGPPTGP 27503



 Score = 35.5 bits (78), Expect = 8.9
 Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 5/80 (6%)

Query: 411  IKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVT--NDG--TLVLKDLDKSDSGTY 465
            ++ M V F C     P P IAWY +G+ +    R  +    DG  +L +  +   D G Y
Sbjct: 1303 LEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIY 1362

Query: 466  TCVASSRHGKYVWSGALLVD 485
            T  AS+  G  + SG L V+
Sbjct: 1363 TAFASNIKGNAICSGKLYVE 1382



 Score = 35.5 bits (78), Expect = 8.9
 Identities = 30/108 (27%), Positives = 44/108 (40%), Gaps = 11/108 (10%)

Query: 503   LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
             +PGPP      +V+   +TL+W      G S + GY VE   R+ +  +        WV 
Sbjct: 30858 IPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVE---RKEVRADR-------WVR 30907

Query: 563   IAR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
             + +  V  T Y    L  G+ Y   V   N+ G   PS  S  +   D
Sbjct: 30908 VNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMD 30955



 Score = 35.5 bits (78), Expect = 8.9
 Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 6/71 (8%)

Query: 134   GSPEPNVYWKKNGQTLLFDGDSRMHLV---DGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
             G P P V W   G+ +      R H+    D   L+I D ++ D G Y     N  G   
Sbjct: 34281 GEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG--- 34337

Query: 191   SAIATLKIHIK 201
             S  AT+ IHI+
Sbjct: 34338 SDSATVNIHIR 34348


>UniRef50_Q4SHH6 Cluster: Chromosome 5 SCAF14581, whole genome
           shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
           Chromosome 5 SCAF14581, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 1515

 Score =  141 bits (341), Expect = 1e-31
 Identities = 178/754 (23%), Positives = 291/754 (38%), Gaps = 82/754 (10%)

Query: 112 LEPESKQSAQGDTVVLECLPPRGSPEP-NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA 170
           +EP+   + +G +  L C     +  P  V WKK+G  +    D R  ++  G+L+    
Sbjct: 15  VEPQDTLAFRGTSAQLNCSAHSDAATPARVEWKKDGTFMSPASDERRRILPDGSLLFTHV 74

Query: 171 -----RQTDAGRYQCIAR-NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR 224
                 + D G YQC+A     G+  S  A L +   P   + P       GSS    C 
Sbjct: 75  VHSKHNKPDEGTYQCVATIENLGSISSRTARLSVAGTPRFTSQPTAATVHQGSSHVMPCE 134

Query: 225 VGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSA 283
           V  D  P   W +      + LG R+  L  G+L + N    D G Y C  EN VG+  +
Sbjct: 135 VNADLAPFARWEKDRQP--LELGARLIQLPSGALVISNASEGDAGLYRCLLEN-VGSSKS 191

Query: 284 SGYLTVYDPPSIN--------LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII 335
           S    ++  P           L P SV    G  A   C  TG P P + W + G++ + 
Sbjct: 192 SDEAQLHVVPEPGQERKLEFLLEPVSVTKVLGATALLPCVVTGYPAPHVRWML-GDKLV- 249

Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD--- 392
                 +      V  G ++   N T+++    T +  + N  G+   + +L+V      
Sbjct: 250 -----EESEGRVEVLGGASLQISNLTEEDAGVYTCMADSAN--GTIEAQAQLSVQVGLVG 302

Query: 393 DDRP---PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND 449
           + +P   PP     P+N         VF C    +P P + W   G+A+I +    +  +
Sbjct: 303 NIQPVGVPPQFVRRPANIYAHESMDIVFECEVSGSPAPSVKWVKNGDAVIPSDYFKIVKE 362

Query: 450 GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTK 509
             L +  L KSD G Y C+A +  G    S  L++    +  +    A      P  P  
Sbjct: 363 HNLQVLGLVKSDEGFYQCLAENEAGNIQSSAQLIILDHGSGGV----ANTAGPTPSAPRD 418

Query: 510 PITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQ 569
            +   V+   + L+W    +      L Y V  +S+E          SR  VV   R  +
Sbjct: 419 LVASLVSTRFIKLTWRPPAEPHGDE-LTYSV-FYSQE--------GTSRERVVNTSRPGE 468

Query: 570 THYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNN 629
               +++L+P   Y F V   NS+G  G S  S +  V     ++ +  G + + +  +N
Sbjct: 469 MQVTIQNLMPDTKYRFRVLAHNSNG-QGES--SAAARVATQCRTVLQVPGPAPNLQAVSN 525

Query: 630 ILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDV 689
             T   +   E TP   +  + +  +L             P+D           +   D 
Sbjct: 526 TPTSVSLSW-EKTPDRKRRHRHLQAVLRRQKRRQRAATKAPVDEPVCPLVQDVDV---DA 581

Query: 690 SGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDD-------------------- 729
               +T L+K T+Y F ++   K   G  +     +TL D                    
Sbjct: 582 QSHTVTGLKKNTEYSFRVVANNKHGPGVSTEDVTVRTLSDGRWSNETTFGWIQQANVCSP 641

Query: 730 ---VPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN 786
              VP  PP N+ + + N+ ++ L+W PP    QNG I  Y +        + +S  + +
Sbjct: 642 SSTVPSAPPQNLTLEVQNSKSIMLRWQPPPPSSQNGEIINYKIKYR---KGSRRSETSDS 698

Query: 787 TTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGP 820
           T+  Q   LI + L  G  YS +++A T+ G GP
Sbjct: 699 TSGSQLFKLI-SGLERGTEYSFRVSAMTVNGTGP 731



 Score =  126 bits (303), Expect = 5e-27
 Identities = 85/295 (28%), Positives = 134/295 (45%), Gaps = 22/295 (7%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P    QP   TV +     + C      +P  RW K    +        LP+G L    A
Sbjct: 112 PRFTSQPTAATVHQGSSHVMPCEVNADLAPFARWEKDRQPLELGARLIQLPSGALVISNA 171

Query: 72  THGRVHSDAGVYWCEATNSYGTARSRNATLHVA-----VLREEFRLEPESKQSAQGDTVV 126
           + G    DAG+Y C   N   +  S  A LHV        + EF LEP S     G T +
Sbjct: 172 SEG----DAGLYRCLLENVGSSKSSDEAQLHVVPEPGQERKLEFLLEPVSVTKVLGATAL 227

Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
           L C+   G P P+V W   G  L+ + + R+ ++ G +L I +  + DAG Y C+A +A 
Sbjct: 228 LPCV-VTGYPAPHVRWML-GDKLVEESEGRVEVLGGASLQISNLTEEDAGVYTCMADSAN 285

Query: 187 GTRES---------AIATLK-IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
           GT E+          +  ++ + + P  +  P ++ A     + F+C V G P P V W 
Sbjct: 286 GTIEAQAQLSVQVGLVGNIQPVGVPPQFVRRPANIYAHESMDIVFECEVSGSPAPSVKWV 345

Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
           ++ G   +P    K++ + +L++  ++ +DEG Y C AEN  G + +S  L + D
Sbjct: 346 KN-GDAVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCLAENEAGNIQSSAQLIILD 399



 Score = 63.7 bits (148), Expect = 3e-08
 Identities = 75/305 (24%), Positives = 123/305 (40%), Gaps = 27/305 (8%)

Query: 203 YLITGPEDVVAQTGSSVTFQCRVGGDPLPD--VLWRRSAGGGNMPLG--RVKVLDDGSLR 258
           +L   P+D +A  G+S    C    D      V W++  G    P    R ++L DGSL 
Sbjct: 12  WLTVEPQDTLAFRGTSAQLNCSAHSDAATPARVEWKKD-GTFMSPASDERRRILPDGSLL 70

Query: 259 LDNVILA-----DEGEYSCEAE-NSVGAVSA-SGYLTVYDPPSINLSPNSVNVESGNVAR 311
             +V+ +     DEG Y C A   ++G++S+ +  L+V   P     P +  V  G+   
Sbjct: 71  FTHVVHSKHNKPDEGTYQCVATIENLGSISSRTARLSVAGTPRFTSQPTAATVHQGSSHV 130

Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371
             C       P   W  E +R  +  G    +  + A       L I++  + D+     
Sbjct: 131 MPCEVNADLAPFARW--EKDRQPLELGARLIQLPSGA-------LVISNASEGDA-GLYR 180

Query: 372 CSAVNYAGS-SFVRGKLTVTSDDDRPPPI-ITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
           C   N   S S    +L V  +  +   +     P + T  + + A+ PC     P P +
Sbjct: 181 CLLENVGSSKSSDEAQLHVVPEPGQERKLEFLLEPVSVTKVLGATALLPCVVTGYPAPHV 240

Query: 430 AWYFEGEALIQNH--RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
            W   G+ L++    R  V    +L + +L + D+G YTC+A S +G       L V   
Sbjct: 241 RWML-GDKLVEESEGRVEVLGGASLQISNLTEEDAGVYTCMADSANGTIEAQAQLSVQVG 299

Query: 488 INPNI 492
           +  NI
Sbjct: 300 LVGNI 304



 Score = 52.0 bits (119), Expect = 1e-04
 Identities = 51/204 (25%), Positives = 84/204 (41%), Gaps = 13/204 (6%)

Query: 639  IEATPIDSKTIKLMWEILNFYYLEGL----FIYFRPLDNITIEYEMKTILHSNDVS-GFE 693
            ++A+ +   TIK+ W     +  + +    F   R   NI    ++K    +N  S  + 
Sbjct: 887  VQASVLSHDTIKVSWADNTLHKSQKITDNRFYTVRWKTNIPANTKVKM---ANTTSLNYM 943

Query: 694  ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTT--TVHLK 751
            +T L+  T YEF ++    +     S +    T + VP   P ++ +        T+ + 
Sbjct: 944  VTGLKPNTLYEFSVMLTRGRRTSTWSMTAQGTTFEAVPSSSPKDVTVVSKENKPRTIIIN 1003

Query: 752  WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811
            W PP     NG ITGY ++    DV A      I   V    +  +  LT   +Y  +I 
Sbjct: 1004 WQPPSEA--NGKITGY-IIYYSTDVNAEDHDWVIEPVVGNRLTHQIQELTLDTTYYFKIQ 1060

Query: 812  AETIIGLGPFSQKVYFNIDSRSVG 835
            A    G+GP S+ V+F    R  G
Sbjct: 1061 ARNSKGMGPMSEAVHFRTPKRPSG 1084



 Score = 50.0 bits (114), Expect = 4e-04
 Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 4/88 (4%)

Query: 9   GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
           G  P  + +P ++           C   GSP+P+++W K G  V+   +  I+    L  
Sbjct: 308 GVPPQFVRRPANIYAHESMDIVFECEVSGSPAPSVKWVKNGDAVIPSDYFKIVKEHNLQV 367

Query: 69  LRATHGRVHSDAGVYWCEATNSYGTARS 96
           L    G V SD G Y C A N  G  +S
Sbjct: 368 L----GLVKSDEGFYQCLAENEAGNIQS 391


>UniRef50_UPI00004D93F2 Cluster: immunoglobulin superfamily, member
            10; n=3; Xenopus tropicalis|Rep: immunoglobulin
            superfamily, member 10 - Xenopus tropicalis
          Length = 2566

 Score =  140 bits (340), Expect = 2e-31
 Identities = 130/481 (27%), Positives = 199/481 (41%), Gaps = 39/481 (8%)

Query: 22   TVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
            TV  +  A + C A G+PSP I W K      VS T R       +    +       D 
Sbjct: 1602 TVLANSDAFIPCEASGNPSPTILWTKVSSGTFVSKTRRVNKMEVFMNGTLSIPSVGIQDG 1661

Query: 81   GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA--QGDTVVLECLPPRGSPEP 138
            G Y C A N  G+ R    TL V        L+  S++     G++V + C    GSP P
Sbjct: 1662 GQYLCVANNQLGSDRLL-VTLSVITYPPRI-LQGRSREITVHSGNSVNVNC-QAEGSPFP 1718

Query: 139  NVYWKKNGQTLLF---DGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195
             + W    +T+ F     + ++ +   G L+I+D    D G Y+C+A N AG     +  
Sbjct: 1719 TITWTLKNETIPFGTSTSNRKIFVQPDGTLIIKDVTVYDRGIYRCLATNLAGEDTFTVRI 1778

Query: 196  LKIHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL----GRVK 250
              I   P ++    + V+A  G ++   C   G+P P V W    G    PL     ++ 
Sbjct: 1779 QVIAAPPVIVEEKRQTVLAGPGENLKIPCTAKGNPQPTVHWVAFDGTKIKPLQYVNAKLF 1838

Query: 251  VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD----PPSINLSPNSVNVES 306
            +  +G+L + NV   D G Y C A +S G+      L V      P   + SP +  +  
Sbjct: 1839 LFSNGTLYIRNVASTDRGNYECIATSSTGSERRVVNLIVEQSDTFPKITDASPKATEMNF 1898

Query: 307  GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG-VTVLTINDTDKND 365
            G+     CTATG P+P + W +     +    + R         +G + V ++ND D  D
Sbjct: 1899 GDKLMLNCTATGEPKPRIIWRLPSKAVV--DQLHRMGSRIQVFPNGTLFVDSVNDKDAGD 1956

Query: 366  SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
                 +C A N  G   +  K++VT    +P  II   P  + +P        C A  +P
Sbjct: 1957 ----YLCVARNKMGDDVILMKVSVTM---KPAKIIQKQPLAKQVPYGKDFKVDCKASGSP 2009

Query: 426  EPIIAWYFEGEALIQN----------HRRNVTND-GTLVLKDLDKSDSGTYTCVASSRHG 474
             P I+W      +I N           RR +  D GTL L  +  ++ G YTC A ++ G
Sbjct: 2010 LPDISWSLPDGTMINNILQADDSGRRKRRYILFDNGTLYLNKVGIAEEGDYTCYAENQLG 2069

Query: 475  K 475
            +
Sbjct: 2070 R 2070



 Score =  126 bits (305), Expect = 3e-27
 Identities = 123/480 (25%), Positives = 205/480 (42%), Gaps = 38/480 (7%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV---VSDTHRSIL--PAGGLFFLRATHG 74
            ++TV       +NC+A GSP P I W      +    S ++R I   P G L     T  
Sbjct: 1697 EITVHSGNSVNVNCQAEGSPFPTITWTLKNETIPFGTSTSNRKIFVQPDGTLIIKDVT-- 1754

Query: 75   RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA---QGDTVVLECLP 131
             V+ D G+Y C ATN  G       T+ + V+     +  E +Q+     G+ + + C  
Sbjct: 1755 -VY-DRGIYRCLATNLAG---EDTFTVRIQVIAAPPVIVEEKRQTVLAGPGENLKIPCTA 1809

Query: 132  PRGSPEPNVYWKK-NGQTL--LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
             +G+P+P V+W   +G  +  L   ++++ L   G L I++   TD G Y+CIA ++ G+
Sbjct: 1810 -KGNPQPTVHWVAFDGTKIKPLQYVNAKLFLFSNGTLYIRNVASTDRGNYECIATSSTGS 1868

Query: 189  RESAIATLKIHIKPY-LIT--GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
                +  +      +  IT   P+      G  +   C   G+P P ++WR  +      
Sbjct: 1869 ERRVVNLIVEQSDTFPKITDASPKATEMNFGDKLMLNCTATGEPKPRIIWRLPSKAVVDQ 1928

Query: 246  L----GRVKVLDDGSLRLDNVILADEGEYSCEAENSVG--AVSASGYLTVYDPPSINLSP 299
            L     R++V  +G+L +D+V   D G+Y C A N +G   +     +T+     I   P
Sbjct: 1929 LHRMGSRIQVFPNGTLFVDSVNDKDAGDYLCVARNKMGDDVILMKVSVTMKPAKIIQKQP 1988

Query: 300  NSVNVESGNVARFTCTATGRPEPTMFWSV-EGN--RTIIFPGMSRDKYHATAVFDGVTVL 356
             +  V  G   +  C A+G P P + WS+ +G     I+    S  +     +FD  T L
Sbjct: 1989 LAKQVPYGKDFKVDCKASGSPLPDISWSLPDGTMINNILQADDSGRRKRRYILFDNGT-L 2047

Query: 357  TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416
             +N     +      C A N  G   ++  +TV +     P I  N  +          +
Sbjct: 2048 YLNKVGIAE-EGDYTCYAENQLGRDEMKVHITVVT---AAPLIKLNMKTRYAAMAGESVI 2103

Query: 417  FPCTAICTPEPIIAWYFEGEALIQ-NHRRNVTND-GTLVLKDLDKSDSGTYTCVASSRHG 474
              C A   P+P I W      +I  +H R + ++ G+L +  +   D+G Y CVA +  G
Sbjct: 2104 LDCEANGEPKPKIFWLLPSSDMIAISHDRYLLHENGSLTVSQVKLLDAGEYMCVARNPAG 2163



 Score =  126 bits (305), Expect = 3e-27
 Identities = 126/500 (25%), Positives = 207/500 (41%), Gaps = 48/500 (9%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK------GGVLVVSDT--- 56
            VT   A  I +QPL   V   +   ++C+A GSP P I W          +L   D+   
Sbjct: 1976 VTMKPAKIIQKQPLAKQVPYGKDFKVDCKASGSPLPDISWSLPDGTMINNILQADDSGRR 2035

Query: 57   -HRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE--FRLE 113
              R IL   G  +L        ++ G Y C A N  G    +   +H+ V+      +L 
Sbjct: 2036 KRRYILFDNGTLYLNKVG---IAEEGDYTCYAENQLGRDEMK---VHITVVTAAPLIKLN 2089

Query: 114  PESKQSAQ-GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ 172
             +++ +A  G++V+L+C    G P+P ++W      ++     R  L + G+L +   + 
Sbjct: 2090 MKTRYAAMAGESVILDC-EANGEPKPKIFWLLPSSDMIAISHDRYLLHENGSLTVSQVKL 2148

Query: 173  TDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG---PEDVVAQTG---SSVTFQCRVG 226
             DAG Y C+ARN AG  ++ +  L++H KP +I G    + ++  T    S     C+  
Sbjct: 2149 LDAGEYMCVARNPAGD-DTKLLRLEVHPKPPIINGLYSNKSIIKDTAIKHSRKLIDCKAE 2207

Query: 227  GDPLPDVLWRRSAG---GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSA 283
            G     V+W               R+ V  +G+L + N+  +D  E++C A N  G    
Sbjct: 2208 GAAPLQVMWIMPDNIYLTAPYHGSRILVHQNGTLEIRNIRPSDTAEFTCVARNDGGESML 2267

Query: 284  SGYLTVYDPPSINLSPNSVN----VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGM 339
               L V +     +  N  N     +S  +A   C A G P P + W +  N T    G 
Sbjct: 2268 VVQLEVLEMLRRPMFKNPFNEKFIAKSSKMAILNCFAEGNPTPEIIWLLP-NGTRFLNGP 2326

Query: 340  SRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPI 399
            S  KYHA +  +G  ++    +   D      C+A N  G  ++  KL +  +  + P I
Sbjct: 2327 SISKYHAGS--NGTFIIY---SPTKDDAGKYRCAARNKVG--YIE-KLIIL-EVGQKPNI 2377

Query: 400  ITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ----NHRRNVTNDGTLVLK 455
            +T+        I       C +   P P + W       I+      R  +  +GTLV++
Sbjct: 2378 LTHPRGPIKSIIGEALSLHCLSDGMPRPSVTWILPSGYAIERPQVQGRYKLLENGTLVIQ 2437

Query: 456  DLDKSDSGTYTCVASSRHGK 475
            +    D G Y C A +  G+
Sbjct: 2438 ETALHDRGNYQCKAKNYAGE 2457



 Score =  126 bits (305), Expect = 3e-27
 Identities = 96/381 (25%), Positives = 160/381 (41%), Gaps = 21/381 (5%)

Query: 22   TVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTH--RSILPAGGLFFLRATHGRVHS 78
            T  +H    ++C+A G+    + W     + + +  H  R ++   G   +R       S
Sbjct: 2193 TAIKHSRKLIDCKAEGAAPLQVMWIMPDNIYLTAPYHGSRILVHQNGTLEIRNIRP---S 2249

Query: 79   DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ--SAQGDTVVLECLPPRGSP 136
            D   + C A N  G +        + +LR      P +++  +      +L C    G+P
Sbjct: 2250 DTAEFTCVARNDGGESMLVVQLEVLEMLRRPMFKNPFNEKFIAKSSKMAILNCFA-EGNP 2308

Query: 137  EPNVYWKKNGQTLLFDGDS--RMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194
             P + W     T   +G S  + H    G  +I    + DAG+Y+C ARN  G  E  I 
Sbjct: 2309 TPEIIWLLPNGTRFLNGPSISKYHAGSNGTFIIYSPTKDDAGKYRCAARNKVGYIEKLII 2368

Query: 195  TLKIHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGG-NMPL--GRVK 250
             L++  KP ++T P   +    G +++  C   G P P V W   +G     P   GR K
Sbjct: 2369 -LEVGQKPNILTHPRGPIKSIIGEALSLHCLSDGMPRPSVTWILPSGYAIERPQVQGRYK 2427

Query: 251  VLDDGSLRLDNVILADEGEYSCEAENSVG--AVSASGYLTVYDPPSINLSPNSVNVESGN 308
            +L++G+L +    L D G Y C+A+N  G  A++ +  +  Y P   N  P +++  +G+
Sbjct: 2428 LLENGTLVIQETALHDRGNYQCKAKNYAGETAITVTVVVVAYPPRITNKPPQTIHTRAGS 2487

Query: 309  VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
              R  C A G P+P +FW +      +    S+     T +      L I +   +DS  
Sbjct: 2488 AVRLNCMAIGIPKPDIFWELPD--LSVLSTASQGSLTGTELLHPQGTLVIQNPQSSDS-G 2544

Query: 369  TIVCSAVNYAGSSFVRGKLTV 389
               C A N  G+   +  L V
Sbjct: 2545 IYKCIAKNSLGTDMSKTYLNV 2565



 Score =  109 bits (262), Expect = 5e-22
 Identities = 122/469 (26%), Positives = 200/469 (42%), Gaps = 42/469 (8%)

Query: 31   LNCRAGGSPSPAIRWYKGGVLVVSDTH-RSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
            L+C A G P P I W      +++ +H R +L   G   L  +  ++  DAG Y C A N
Sbjct: 2104 LDCEANGEPKPKIFWLLPSSDMIAISHDRYLLHENGS--LTVSQVKL-LDAGEYMCVARN 2160

Query: 90   SYGT-ARSRNATLHVA--VLREEFRLEPESKQSA-QGDTVVLECLPPRGSPEPNVYWKKN 145
              G   +     +H    ++   +  +   K +A +    +++C    G+    V W   
Sbjct: 2161 PAGDDTKLLRLEVHPKPPIINGLYSNKSIIKDTAIKHSRKLIDC-KAEGAAPLQVMWIMP 2219

Query: 146  GQTLL---FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA--TLKIHI 200
                L   + G SR+ +   G L I++ R +D   + C+ARN  G     +    L++  
Sbjct: 2220 DNIYLTAPYHG-SRILVHQNGTLEIRNIRPSDTAEFTCVARNDGGESMLVVQLEVLEMLR 2278

Query: 201  KPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG--NMP-LGRVKVLDDG 255
            +P +   P  E  +A++       C   G+P P+++W    G    N P + +     +G
Sbjct: 2279 RP-MFKNPFNEKFIAKSSKMAILNCFAEGNPTPEIIWLLPNGTRFLNGPSISKYHAGSNG 2337

Query: 256  SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS-VNVESGNVARFTC 314
            +  + +    D G+Y C A N VG +     L V   P+I   P   +    G      C
Sbjct: 2338 TFIIYSPTKDDAGKYRCAARNKVGYIEKLIILEVGQKPNILTHPRGPIKSIIGEALSLHC 2397

Query: 315  TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
             + G P P++ W +     I  P + + +Y    + +  T L I +T  +D R    C A
Sbjct: 2398 LSDGMPRPSVTWILPSGYAIERPQV-QGRYK---LLENGT-LVIQETALHD-RGNYQCKA 2451

Query: 375  VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK--SMAVFPCTAICTPEPIIAWY 432
             NYAG + +    TVT      PP ITN P  QT+  +  S     C AI  P+P I W 
Sbjct: 2452 KNYAGETAI----TVTVVVVAYPPRITNKPP-QTIHTRAGSAVRLNCMAIGIPKPDIFWE 2506

Query: 433  FEGEALIQNHRR-NVTN------DGTLVLKDLDKSDSGTYTCVASSRHG 474
                +++    + ++T        GTLV+++   SDSG Y C+A +  G
Sbjct: 2507 LPDLSVLSTASQGSLTGTELLHPQGTLVIQNPQSSDSGIYKCIAKNSLG 2555



 Score =  105 bits (253), Expect = 6e-21
 Identities = 86/301 (28%), Positives = 139/301 (46%), Gaps = 24/301 (7%)

Query: 188  TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTF-QCRVGGDPLPDVLWRRSAGGGNMP- 245
            T  ++ +T     KP +I G         +S  F  C   G+P P +LW + + G  +  
Sbjct: 1577 TVSTSFSTQNSRSKPRIIGGKAASFTVLANSDAFIPCEASGNPSPTILWTKVSSGTFVSK 1636

Query: 246  ---LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV--YDPPSINLSPN 300
               + +++V  +G+L + +V + D G+Y C A N +G+      L+V  Y P  +     
Sbjct: 1637 TRRVNKMEVFMNGTLSIPSVGIQDGGQYLCVANNQLGSDRLLVTLSVITYPPRILQGRSR 1696

Query: 301  SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
             + V SGN     C A G P PT+ W+++ N TI F G S          DG   L I D
Sbjct: 1697 EITVHSGNSVNVNCQAEGSPFPTITWTLK-NETIPF-GTSTSNRKIFVQPDG--TLIIKD 1752

Query: 361  TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL--PIKSMAVFP 418
                D R    C A N AG      ++ V +     PP+I        L  P +++ + P
Sbjct: 1753 VTVYD-RGIYRCLATNLAGEDTFTVRIQVIA----APPVIVEEKRQTVLAGPGENLKI-P 1806

Query: 419  CTAICTPEPIIAWY-FEGEAL--IQ--NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
            CTA   P+P + W  F+G  +  +Q  N +  + ++GTL ++++  +D G Y C+A+S  
Sbjct: 1807 CTAKGNPQPTVHWVAFDGTKIKPLQYVNAKLFLFSNGTLYIRNVASTDRGNYECIATSST 1866

Query: 474  G 474
            G
Sbjct: 1867 G 1867



 Score = 61.3 bits (142), Expect = 2e-07
 Identities = 72/267 (26%), Positives = 110/267 (41%), Gaps = 18/267 (6%)

Query: 301  SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
            S  V + + A   C A+G P PT+ W+   + T  F   +R + +   VF   T L+I  
Sbjct: 1600 SFTVLANSDAFIPCEASGNPSPTILWTKVSSGT--FVSKTR-RVNKMEVFMNGT-LSIPS 1655

Query: 361  TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ-TLPIKSMAVFPC 419
                D     +C A N  GS     +L VT      PP I  G S + T+   +     C
Sbjct: 1656 VGIQDG-GQYLCVANNQLGSD----RLLVTLSVITYPPRILQGRSREITVHSGNSVNVNC 1710

Query: 420  TAICTPEPIIAWYFEGEAL-----IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
             A  +P P I W  + E +       N +  V  DGTL++KD+   D G Y C+A++  G
Sbjct: 1711 QAEGSPFPTITWTLKNETIPFGTSTSNRKIFVQPDGTLIIKDVTVYDRGIYRCLATNLAG 1770

Query: 475  KYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSW--SQNNKIGS 532
            +  ++  + V +   P I   +   V + PG   K       +   T+ W      KI  
Sbjct: 1771 EDTFTVRIQVIA-APPVIVEEKRQTVLAGPGENLKIPCTAKGNPQPTVHWVAFDGTKIKP 1829

Query: 533  SSILGYQVEVFSRETLSGNNTPRNSRG 559
               +  ++ +FS  TL   N     RG
Sbjct: 1830 LQYVNAKLFLFSNGTLYIRNVASTDRG 1856



 Score = 57.2 bits (132), Expect = 3e-06
 Identities = 45/163 (27%), Positives = 71/163 (43%), Gaps = 11/163 (6%)

Query: 31  LNCRAGGSPSPAIRWY-----KGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85
           ++C   G P+PAI W      K      S   R  +   G F L++     + D G+Y C
Sbjct: 492 MDCEVLGEPTPAIEWILPDGSKIRAPYASQEGRITITKNGKFILKSAD---NFDTGIYHC 548

Query: 86  EATNSYGT-ARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK 144
            ATN       S   T+  + + E+F    E   S  GD + L C    G P+ +V W  
Sbjct: 549 IATNYIDADVLSFRITVVSSDVEEQFVNGVELSVS-NGDYINLPC-GSSGVPDASVSWIL 606

Query: 145 NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
              ++L++      ++  G L IQ   + D+G ++C+A N  G
Sbjct: 607 PDHSVLYEPSRNKIILANGTLKIQGISERDSGHFRCLAANQYG 649



 Score = 54.0 bits (124), Expect = 2e-05
 Identities = 41/180 (22%), Positives = 75/180 (41%), Gaps = 9/180 (5%)

Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
           G      C   G P P + W +     I  P  S++    T   +G  +L   D   N  
Sbjct: 487 GGTVEMDCEVLGEPTPAIEWILPDGSKIRAPYASQEG-RITITKNGKFILKSAD---NFD 542

Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
                C A NY  +  +  ++TV S D        NG    ++        PC +   P+
Sbjct: 543 TGIYHCIATNYIDADVLSFRITVVSSDVEEQ--FVNGVE-LSVSNGDYINLPCGSSGVPD 599

Query: 427 PIIAWYFEGEALIQNHRRN--VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
             ++W     +++    RN  +  +GTL ++ + + DSG + C+A++++G  + +  +LV
Sbjct: 600 ASVSWILPDHSVLYEPSRNKIILANGTLKIQGISERDSGHFRCLAANQYGLDILTHRVLV 659



 Score = 49.2 bits (112), Expect = 7e-04
 Identities = 41/165 (24%), Positives = 65/165 (39%), Gaps = 9/165 (5%)

Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTL---LFDGDSRMHLVDGGNLVIQDARQTDAGR 177
           G TV ++C    G P P + W   +G  +       + R+ +   G  +++ A   D G 
Sbjct: 487 GGTVEMDC-EVLGEPTPAIEWILPDGSKIRAPYASQEGRITITKNGKFILKSADNFDTGI 545

Query: 178 YQCIARNA--AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
           Y CIA N   A      I  +   ++   + G E  V+  G  +   C   G P   V W
Sbjct: 546 YHCIATNYIDADVLSFRITVVSSDVEEQFVNGVELSVSN-GDYINLPCGSSGVPDASVSW 604

Query: 236 RRSAGGGNMPLGRVKV-LDDGSLRLDNVILADEGEYSCEAENSVG 279
                       R K+ L +G+L++  +   D G + C A N  G
Sbjct: 605 ILPDHSVLYEPSRNKIILANGTLKIQGISERDSGHFRCLAANQYG 649



 Score = 45.2 bits (102), Expect = 0.011
 Identities = 34/136 (25%), Positives = 56/136 (41%), Gaps = 7/136 (5%)

Query: 213 AQTGSSVTFQCRVGGDPLPDVLWRRSAGGG-NMPL----GRVKVLDDGSLRLDNVILADE 267
           A  G +V   C V G+P P + W    G     P     GR+ +  +G   L +    D 
Sbjct: 484 AVIGGTVEMDCEVLGEPTPAIEWILPDGSKIRAPYASQEGRITITKNGKFILKSADNFDT 543

Query: 268 GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV--NVESGNVARFTCTATGRPEPTMF 325
           G Y C A N + A   S  +TV          N V  +V +G+     C ++G P+ ++ 
Sbjct: 544 GIYHCIATNYIDADVLSFRITVVSSDVEEQFVNGVELSVSNGDYINLPCGSSGVPDASVS 603

Query: 326 WSVEGNRTIIFPGMSR 341
           W +  +  +  P  ++
Sbjct: 604 WILPDHSVLYEPSRNK 619


>UniRef50_UPI0000DB6D93 Cluster: PREDICTED: similar to CG32387-PB,
           isoform B; n=3; Apocrita|Rep: PREDICTED: similar to
           CG32387-PB, isoform B - Apis mellifera
          Length = 792

 Score =  138 bits (335), Expect = 6e-31
 Identities = 111/371 (29%), Positives = 167/371 (45%), Gaps = 38/371 (10%)

Query: 122 GDTVVLECLPPRGSPEPNVYWKKN---GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY 178
           G+T+VL C+  +G P P   W +    G  ++F+ + R++    G LV+Q AR  DAGRY
Sbjct: 204 GETIVLSCIS-QGIPPPMYLWFRESVTGTAMIFNSE-RIY-ARAGVLVLQSARAEDAGRY 260

Query: 179 QCIARNAAGTRE-----SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233
            C A N AG+       S I++L IH+ P      + V    G    FQC V G P+P +
Sbjct: 261 VCHANNTAGSEMVELEVSIISSLSIHLVP------QQVTVDLGKDAEFQCSVTGQPIPVI 314

Query: 234 LWRRSA-GGGNMPLGRVKVL-DDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290
            W +     G    GR K+  +DGS LR+ +V+  D+G Y C A+N    V A+  L + 
Sbjct: 315 FWTKDGLPVGESASGRSKITGNDGSTLRISSVVRDDKGMYQCFAKNDYEMVQATAELRLG 374

Query: 291 DP-PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY----H 345
           D  P +        ++ G      C ATG P P   W+++G     FP    D++    +
Sbjct: 375 DAAPQLLYKFIEQTIQPGPSVSLKCIATGNPTPHFSWTLDG-----FPLPQNDRFMIGQY 429

Query: 346 ATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPS 405
            T   D ++ + I+     D      C+A N         +L +       P +   G  
Sbjct: 430 VTVHGDVISHVNISVVHVEDG-GEYRCTAANRMAKVHHSARLNIYG----LPHVRPMG-- 482

Query: 406 NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS-DSGT 464
           N         V  C     P   I W  +G+ L  + R+ V  +GTLVL  +D+S D G 
Sbjct: 483 NYAAVAGETTVIKCPVAGFPIASITWEKDGKVLPTSRRQEVFPNGTLVLHHVDRSTDHGA 542

Query: 465 YTCVASSRHGK 475
           YTC A ++ G+
Sbjct: 543 YTCTAKNKQGR 553



 Score =  128 bits (309), Expect = 9e-28
 Identities = 131/480 (27%), Positives = 200/480 (41%), Gaps = 39/480 (8%)

Query: 31  LNCRAGGSPSPAIRWYKGGVL-VVSDTH-RSILPAGGLFFLR--ATHGRVHSDAGVYWCE 86
           ++C A GSP P I W  G    V+   H R +L  G ++FL   A   R    + VY C+
Sbjct: 2   IHCSAQGSPLPRIDWLMGDESPVLPIPHIREMLVNGSMYFLPFGAETYRHDVHSAVYRCQ 61

Query: 87  ATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE--PNVYWKK 144
           A+NS G    R  T+  AV+R+++ ++        G+T VL C  P    E      W +
Sbjct: 62  ASNSVGRVLGREITVK-AVVRQKYEVQVRDAYVLPGNTGVLRCEIPTFVKEYVAVTSWVR 120

Query: 145 NGQTLLFD---GDSRMHLVDGGNLVIQDARQTDA-GRYQC--IARNAAGTRESAIATLKI 198
           +    +F     D R H++  G L++     +DA   Y+C  + R    T ES+     +
Sbjct: 121 DSAYNIFPTPKSDDRHHMLPTGELLVFSVTSSDAQSSYRCRTVHRVTGDTVESSSYARLV 180

Query: 199 HIKPYLITGPE------DVVAQTGSSVTFQCRVGGDPLPDVLW-RRSAGGGNMPLGRVKV 251
              P+    P           +TG ++   C   G P P  LW R S  G  M     ++
Sbjct: 181 VTDPHTPVPPRFNERVSPAPIRTGETIVLSCISQGIPPPMYLWFRESVTGTAMIFNSERI 240

Query: 252 LDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310
               G L L +    D G Y C A N+ G+      +++    SI+L P  V V+ G  A
Sbjct: 241 YARAGVLVLQSARAEDAGRYVCHANNTAGSEMVELEVSIISSLSIHLVPQQVTVDLGKDA 300

Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
            F C+ TG+P P +FW+ +G    +  G S          DG T L I+   ++D +   
Sbjct: 301 EFQCSVTGQPIPVIFWTKDG----LPVGESASGRSKITGNDGST-LRISSVVRDD-KGMY 354

Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA 430
            C A N         +L +    D  P ++         P  S+++  C A   P P  +
Sbjct: 355 QCFAKNDYEMVQATAELRL---GDAAPQLLYKFIEQTIQPGPSVSL-KCIATGNPTPHFS 410

Query: 431 WYFEGEALIQNHR----RNVTNDGTLV----LKDLDKSDSGTYTCVASSRHGKYVWSGAL 482
           W  +G  L QN R    + VT  G ++    +  +   D G Y C A++R  K   S  L
Sbjct: 411 WTLDGFPLPQNDRFMIGQYVTVHGDVISHVNISVVHVEDGGEYRCTAANRMAKVHHSARL 470



 Score =  111 bits (268), Expect = 8e-23
 Identities = 128/497 (25%), Positives = 197/497 (39%), Gaps = 47/497 (9%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG---GVLVVSDTHRSILPAGGLFF 68
           P   E+     +   +   L+C + G P P   W++    G  ++ ++ R I    G+  
Sbjct: 190 PRFNERVSPAPIRTGETIVLSCISQGIPPPMYLWFRESVTGTAMIFNSER-IYARAGVLV 248

Query: 69  LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVL 127
           L++       DAG Y C A N   TA S    L V+++      L P+      G     
Sbjct: 249 LQSARAE---DAGRYVCHANN---TAGSEMVELEVSIISSLSIHLVPQQVTVDLGKDAEF 302

Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV--DGGNLVIQDARQTDAGRYQCIARNA 185
           +C    G P P ++W K+G  +      R  +   DG  L I    + D G YQC A+N 
Sbjct: 303 QC-SVTGQPIPVIFWTKDGLPVGESASGRSKITGNDGSTLRISSVVRDDKGMYQCFAKND 361

Query: 186 AGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA----G 240
               + A A L++    P L+    +   Q G SV+ +C   G+P P   W         
Sbjct: 362 YEMVQ-ATAELRLGDAAPQLLYKFIEQTIQPGPSVSLKCIATGNPTPHFSWTLDGFPLPQ 420

Query: 241 GGNMPLGR-VKVLDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
                +G+ V V  D    + +  V + D GEY C A N +  V  S  L +Y  P +  
Sbjct: 421 NDRFMIGQYVTVHGDVISHVNISVVHVEDGGEYRCTAANRMAKVHHSARLNIYGLPHVRP 480

Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
             N   V +G      C   G P  ++ W  +G    + P   R +     VF   T L 
Sbjct: 481 MGNYAAV-AGETTVIKCPVAGFPIASITWEKDGK---VLPTSRRQE-----VFPNGT-LV 530

Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT-NGPSNQTLPIKSMAV 416
           ++  D++       C+A N  G S      TV  +   PP I   + P+N     +   V
Sbjct: 531 LHHVDRSTDHGAYTCTAKNKQGRS---DSQTVHIEVKVPPKIDPFSFPANIQEGARVHVV 587

Query: 417 FPCTAICTPEPI-IAWYFEGEALIQNHRRNVTN-----DGTLVLKDLDKSDSGTYTCVAS 470
             C       P+ I W  +G  L  N     T+     D TL+++    + +G YTCVAS
Sbjct: 588 --CVVSEGDSPLKITWLKDGRPL--NSTETTTHHIGEYDLTLMIQSATTAHNGNYTCVAS 643

Query: 471 SRHGKYVWSGALLVDSP 487
           +   +   + +LLV  P
Sbjct: 644 NDAAETSRTASLLVHVP 660



 Score = 95.9 bits (228), Expect = 6e-18
 Identities = 85/330 (25%), Positives = 136/330 (41%), Gaps = 17/330 (5%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI---LPAGGLF 67
           AP ++ + ++ T+      +L C A G+P+P   W   G  +  +    I   +   G  
Sbjct: 377 APQLLYKFIEQTIQPGPSVSLKCIATGNPTPHFSWTLDGFPLPQNDRFMIGQYVTVHGDV 436

Query: 68  FLRATHGRVH-SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTV 125
                   VH  D G Y C A N        +A L++  L     + P    +A  G+T 
Sbjct: 437 ISHVNISVVHVEDGGEYRCTAANRMAKVH-HSARLNIYGLPH---VRPMGNYAAVAGETT 492

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA-RQTDAGRYQCIARN 184
           V++C P  G P  ++ W+K+G+ L      R  +   G LV+    R TD G Y C A+N
Sbjct: 493 VIKC-PVAGFPIASITWEKDGKVL--PTSRRQEVFPNGTLVLHHVDRSTDHGAYTCTAKN 549

Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGN 243
             G  +S    +++ + P +         Q G+ V   C V  GD    + W +     N
Sbjct: 550 KQGRSDSQTVHIEVKVPPKIDPFSFPANIQEGARVHVVCVVSEGDSPLKITWLKDGRPLN 609

Query: 244 MPLGRVKVLD--DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
                   +   D +L + +   A  G Y+C A N     S +  L V+ PP+I     +
Sbjct: 610 STETTTHHIGEYDLTLMIQSATTAHNGNYTCVASNDAAETSRTASLLVHVPPTIAPFSFN 669

Query: 302 VNVESGNVARFTC-TATGRPEPTMFWSVEG 330
            ++  G  A+ TC    G P  T+ WS +G
Sbjct: 670 KDLSEGVRAQVTCMVEKGDPPFTIAWSKDG 699



 Score = 95.5 bits (227), Expect = 8e-18
 Identities = 126/504 (25%), Positives = 202/504 (40%), Gaps = 56/504 (11%)

Query: 18  PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRV 76
           P  VTV   + A   C   G P P I W K G+ V  S + RS +       LR +   V
Sbjct: 289 PQQVTVDLGKDAEFQCSVTGQPIPVIFWTKDGLPVGESASGRSKITGNDGSTLRIS-SVV 347

Query: 77  HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
             D G+Y C A N Y   ++  A L +     +   +   +    G +V L+C+   G+P
Sbjct: 348 RDDKGMYQCFAKNDYEMVQA-TAELRLGDAAPQLLYKFIEQTIQPGPSVSLKCI-ATGNP 405

Query: 137 EPNVYWKKNGQTLLFDGDSRM---HLVDGGNLV----IQDARQTDAGRYQCIARNAAGTR 189
            P+  W  +G  L    D  M   ++   G+++    I      D G Y+C A N     
Sbjct: 406 TPHFSWTLDGFPLP-QNDRFMIGQYVTVHGDVISHVNISVVHVEDGGEYRCTAANRMAKV 464

Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-R 248
             + A L I+  P+ +    +  A  G +   +C V G P+  + W +   G  +P   R
Sbjct: 465 HHS-ARLNIYGLPH-VRPMGNYAAVAGETTVIKCPVAGFPIASITWEKD--GKVLPTSRR 520

Query: 249 VKVLDDGSLRLDNVILA-DEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSPNSVNVES 306
            +V  +G+L L +V  + D G Y+C A+N  G + S + ++ V  PP I+      N++ 
Sbjct: 521 QEVFPNGTLVLHHVDRSTDHGAYTCTAKNKQGRSDSQTVHIEVKVPPKIDPFSFPANIQE 580

Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
           G      C  +    P     ++  R +     +    H    +D +T++  + T  ++ 
Sbjct: 581 GARVHVVCVVSEGDSPLKITWLKDGRPL---NSTETTTHHIGEYD-LTLMIQSATTAHNG 636

Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
             T  C A N A  +     L V       PP I     N+ L     A   C       
Sbjct: 637 NYT--CVASNDAAETSRTASLLV-----HVPPTIAPFSFNKDLSEGVRAQVTCMVEKGDP 689

Query: 427 PI-IAWYFEGEAL--------------IQNHRR-------NVTN----DGTLVLKDLDKS 460
           P  IAW  +GEA+              I   R         VTN      T+V++ +  +
Sbjct: 690 PFTIAWSKDGEAIAGPSPAAAGFGNTGITGPRHTQTPAGLRVTNIDAHSSTIVIERVSAA 749

Query: 461 DSGTYTCVASSRHGKYVWSGALLV 484
            SG YTC+A +   + +W+  L+V
Sbjct: 750 HSGNYTCMARNSVAEVLWTAELIV 773


>UniRef50_O97394 Cluster: Protein sidekick precursor; n=9;
           Endopterygota|Rep: Protein sidekick precursor -
           Drosophila melanogaster (Fruit fly)
          Length = 2224

 Score =  138 bits (334), Expect = 9e-31
 Identities = 190/756 (25%), Positives = 297/756 (39%), Gaps = 74/756 (9%)

Query: 39  PSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRN 98
           P P++ W      +  D   +   A  L  L A      +D   Y  +A N+       +
Sbjct: 189 PVPSVMWQSEDGPLNYDIKYAFTHANQLIILSADE----NDRKGYRAKAINTQLGKEESS 244

Query: 99  ATLHVAV-------LREEFRLEPESKQSAQGDTVV-LECLP-PRGSPEPNVYWKKNGQTL 149
           A +H+ V       +  E  + P+  +   G  VV L+C+   R   E    W K+G  +
Sbjct: 245 AFVHLNVSGDPYIEVAPEIIVRPQDVKVKVGTGVVELQCIANARPLHELETLWLKDGLAV 304

Query: 150 LFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI-KPYLIT 206
              G  R  L D  N  L +  A  + +G Y C  R  +G   +  A+ ++ I +P L  
Sbjct: 305 ETAG-VRHTLNDPWNRTLALLQANSSHSGEYTCQVRLRSGGYPAVSASARLQILEPPLFF 363

Query: 207 GP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPLGRVKVLDDGSLRLDNV 262
            P   +   + G  V   C V G+P P V W R+A     ++  GR  +  D +L +  +
Sbjct: 364 TPMRAETFGEFGGQVQLTCDVVGEPTPQVKWFRNAESVDAHIESGRYTLNTDNTLVIKKL 423

Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVY-DPPSINLSPNSVNVESGNVARFTCTATGRPE 321
           IL D   + C A N  G  SAS +L V    P + L P +V    G  A  +C A G P 
Sbjct: 424 ILDDAAMFQCLAINEAGENSASTWLRVKTSAPIMELPPQNVTALDGKDATISCRAVGSPN 483

Query: 322 PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381
           P + W    N T +    SR       + +   +L  N   ++      +C   N AGS 
Sbjct: 484 PNITWIY--NETQLVDISSR-----VQILESGDLLISN--IRSVDAGLYICVRANEAGSV 534

Query: 382 FVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE-PI-IAWYFEGEAL- 438
                L+V          I   P + T+ +   A   C     P  P  I WY EG++  
Sbjct: 535 KGEAYLSVLVRTQ-----IIQPPVDTTVLLGLTATLQCKVSSDPSVPYNIDWYREGQSST 589

Query: 439 -IQNHRR-NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL-LVDSPINPNIHFF 495
            I N +R  V  DG L ++ +  SD G+Y CV +S  G    +  L +++ P  P+    
Sbjct: 590 PISNSQRIGVQADGQLEIQAVRASDVGSYACVVTSPGGNETRAARLSVIELPFPPS---- 645

Query: 496 RAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPR 555
               V  LP P  + I     + S T  +  N+ I  S  +  + EV   E   G   P 
Sbjct: 646 -NVKVERLPEPQQRSI-----NVSWTPGFDGNSPI--SKFIIQRREVSELEKFVG-PVPD 696

Query: 556 NSRGWVVIARRV--HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNS 613
               W+     V   Q   ++++L     Y F V   N  G   PS  S+ V +  ++ S
Sbjct: 697 PLLNWITELSNVSADQRWILLENLKAATVYQFRVSAVNRVGEGSPSEPSNVVELPQEAPS 756

Query: 614 LWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDN 673
                G   S    + I+T          P++        +IL +     LF Y    +N
Sbjct: 757 -GPPVGFVGSARSMSEIITQW------QPPLEEHR---NGQILGYILRYRLFGY----NN 802

Query: 674 ITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDG 733
           +   Y+  T   +     F I  L  +  Y   +  +     G  +     +T + VP+ 
Sbjct: 803 VPWSYQNIT---NEAQRNFLIQELITWKDYIVQIAAYNNMGVGVYTEGSKIKTKEGVPEA 859

Query: 734 PPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNV 769
           PP N+++  +N+T    +W+PP  Q  NGI  GY +
Sbjct: 860 PPTNVKVEAINSTAARCRWTPPNPQQINGINQGYKI 895



 Score =  111 bits (267), Expect = 1e-22
 Identities = 123/465 (26%), Positives = 183/465 (39%), Gaps = 46/465 (9%)

Query: 31  LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
           L C A G P P  RW K GV  V D   S        F R  H     DAG Y C A N 
Sbjct: 93  LQCHALGYPQPTYRWLKDGV-PVGDFSSS-------QFYR-FHSTRREDAGSYQCIARND 143

Query: 91  YGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
            G+  S  + + VA +   F    E + +   G   + +  P    P P+V W+     L
Sbjct: 144 AGSIFSEKSDVVVAYM-GIFENTTEGRLTVISGHPAIFDMPPIESIPVPSVMWQSEDGPL 202

Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK--------IHIK 201
            +  D +        L+I  A + D   Y+  A N    +E + A +         I + 
Sbjct: 203 NY--DIKYAFTHANQLIILSADENDRKGYRAKAINTQLGKEESSAFVHLNVSGDPYIEVA 260

Query: 202 PYLITGPEDVVAQTGSSVT-FQCRVGGDPLPDV--LWRRSAGGGNMPLGRVKVLDD---G 255
           P +I  P+DV  + G+ V   QC     PL ++  LW +  G      G    L+D    
Sbjct: 261 PEIIVRPQDVKVKVGTGVVELQCIANARPLHELETLWLKD-GLAVETAGVRHTLNDPWNR 319

Query: 256 SLRLDNVILADEGEYSCEAENSVG---AVSASGYLTVYDPPSINLSPNSVNV--ESGNVA 310
           +L L     +  GEY+C+     G   AVSAS  L + +PP +  +P       E G   
Sbjct: 320 TLALLQANSSHSGEYTCQVRLRSGGYPAVSASARLQILEPP-LFFTPMRAETFGEFGGQV 378

Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
           + TC   G P P + W    N   +   +   +Y      +    L I     +D+    
Sbjct: 379 QLTCDVVGEPTPQVKWF--RNAESVDAHIESGRY----TLNTDNTLVIKKLILDDAA-MF 431

Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA 430
            C A+N AG +     L V +      PI+   P N T      A   C A+ +P P I 
Sbjct: 432 QCLAINEAGENSASTWLRVKTS----APIMELPPQNVTALDGKDATISCRAVGSPNPNIT 487

Query: 431 WYFEGEALIQ-NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
           W +    L+  + R  +   G L++ ++   D+G Y CV ++  G
Sbjct: 488 WIYNETQLVDISSRVQILESGDLLISNIRSVDAGLYICVRANEAG 532



 Score = 98.3 bits (234), Expect = 1e-18
 Identities = 88/317 (27%), Positives = 128/317 (40%), Gaps = 10/317 (3%)

Query: 11  APYIIEQPLDVTVARHQPAT-LNCRAGGSPSPAIR--WYKGGVLVVSDTHRSILPAGGLF 67
           AP II +P DV V        L C A   P   +   W K G+ V +   R  L      
Sbjct: 260 APEIIVRPQDVKVKVGTGVVELQCIANARPLHELETLWLKDGLAVETAGVRHTLNDPWNR 319

Query: 68  FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ--GDTV 125
            L        S +G Y C+     G   + +A+  + +L       P   ++    G  V
Sbjct: 320 TLALLQAN-SSHSGEYTCQVRLRSGGYPAVSASARLQILEPPLFFTPMRAETFGEFGGQV 378

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARN 184
            L C    G P P V W +N +++    +S  + ++  N LVI+     DA  +QC+A N
Sbjct: 379 QLTC-DVVGEPTPQVKWFRNAESVDAHIESGRYTLNTDNTLVIKKLILDDAAMFQCLAIN 437

Query: 185 AAGTRESAIATLKIHIK-PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
            AG   SA   L++    P +   P++V A  G   T  CR  G P P++ W  +     
Sbjct: 438 EAG-ENSASTWLRVKTSAPIMELPPQNVTALDGKDATISCRAVGSPNPNITWIYNETQLV 496

Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
               RV++L+ G L + N+   D G Y C   N  G+V    YL+V     I   P    
Sbjct: 497 DISSRVQILESGDLLISNIRSVDAGLYICVRANEAGSVKGEAYLSVLVRTQIIQPPVDTT 556

Query: 304 VESGNVARFTCTATGRP 320
           V  G  A   C  +  P
Sbjct: 557 VLLGLTATLQCKVSSDP 573



 Score = 65.3 bits (152), Expect = 1e-08
 Identities = 89/387 (22%), Positives = 151/387 (39%), Gaps = 40/387 (10%)

Query: 110 FRLEPESKQS--AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVI 167
           F   P S  S  ++G T +L+C    G P+P   W K+G  +     S+ +         
Sbjct: 74  FTTHPSSSGSIVSEGSTKILQC-HALGYPQPTYRWLKDGVPVGDFSSSQFYR-------F 125

Query: 168 QDARQTDAGRYQCIARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQC-RV 225
              R+ DAG YQCIARN AG+  S  + + + ++  +  T    +   +G    F    +
Sbjct: 126 HSTRREDAGSYQCIARNDAGSIFSEKSDVVVAYMGIFENTTEGRLTVISGHPAIFDMPPI 185

Query: 226 GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENS-VGAVSAS 284
              P+P V+W+   G  N  + +        L + +    D   Y  +A N+ +G   +S
Sbjct: 186 ESIPVPSVMWQSEDGPLNYDI-KYAFTHANQLIILSADENDRKGYRAKAINTQLGKEESS 244

Query: 285 GYLTVY---DP-----PSINLSPNSVNVESG-NVARFTCTATGRP--EPTMFWSVEG--N 331
            ++ +    DP     P I + P  V V+ G  V    C A  RP  E    W  +G   
Sbjct: 245 AFVHLNVSGDPYIEVAPEIIVRPQDVKVKVGTGVVELQCIANARPLHELETLWLKDGLAV 304

Query: 332 RTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTS 391
            T        D ++ T     + +L  N +   +    +   +  Y   S    +L +  
Sbjct: 305 ETAGVRHTLNDPWNRT-----LALLQANSSHSGEYTCQVRLRSGGYPAVS-ASARLQIL- 357

Query: 392 DDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL---IQNHRRNVTN 448
               PP   T   +             C  +  P P + W+   E++   I++ R  +  
Sbjct: 358 ---EPPLFFTPMRAETFGEFGGQVQLTCDVVGEPTPQVKWFRNAESVDAHIESGRYTLNT 414

Query: 449 DGTLVLKDLDKSDSGTYTCVASSRHGK 475
           D TLV+K L   D+  + C+A +  G+
Sbjct: 415 DNTLVIKKLILDDAAMFQCLAINEAGE 441



 Score = 60.5 bits (140), Expect = 3e-07
 Identities = 47/200 (23%), Positives = 85/200 (42%), Gaps = 13/200 (6%)

Query: 639  IEATPIDSKTIKLMWEILNFYYLEG------LFIYFRPLDNI--TIEYEMKTILHSNDVS 690
            ++  PI + ++++ W  L      G        I ++ L +    ++   KT +H  + +
Sbjct: 1579 LKVVPITTTSVRVQWSALETALWNGDASTGGYRILYQQLSDFPTALQSTPKTDVHGINEN 1638

Query: 691  GFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHL 750
               ++ L++   YE  ++PF  +  G  +        + VP G P  ++   +++T V L
Sbjct: 1639 SVVLSDLQQDRNYEIVVLPFNSQGPGPATPPAAVYVGEAVPTGEPRAVDAAPISSTEVRL 1698

Query: 751  KWSPPELQLQNGIITGYNV--VVNWLD---VPANKSMVAINTTVHQATSLIMTNLTSGVS 805
             W PP+  +QNG I GY +  +V +      P  K    I      ATS  +  L     
Sbjct: 1699 LWKPPKQSMQNGDILGYKIYYLVTYSPQALEPGRKWEEEIEVVSATATSHSLVFLDKFTE 1758

Query: 806  YSVQIAAETIIGLGPFSQKV 825
            Y +Q+ A    G GP S  +
Sbjct: 1759 YRIQLLAFNPAGDGPRSAPI 1778



 Score = 54.0 bits (124), Expect = 2e-05
 Identities = 37/123 (30%), Positives = 59/123 (47%), Gaps = 6/123 (4%)

Query: 697  LRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPE 756
            L K+T+Y   ++ F    +G  S+     T+DDVPD     +    ++  +V + W+PP 
Sbjct: 935  LEKFTEYNISVLCFTDPGDGVASSQVAVMTMDDVPD-EVTGLHFDDVSDRSVKVLWAPP- 992

Query: 757  LQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETII 816
             +  NGI+TGY V     D P   ++ + N T    T L +  L +   Y  +I A T +
Sbjct: 993  -RASNGILTGYTVRYQVKDRP--DTLKSFNLTADD-TELTVNQLQATTHYWFEIVAWTRV 1048

Query: 817  GLG 819
            G G
Sbjct: 1049 GSG 1051



 Score = 54.0 bits (124), Expect = 2e-05
 Identities = 41/151 (27%), Positives = 75/151 (49%), Gaps = 7/151 (4%)

Query: 675  TIEYEMKTI-LHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDG 733
            TI+Y  +++ +  +  +   + SL ++T YE  +         K S++ V +T + VP  
Sbjct: 1215 TIKYVPRSVVIEDHTANSHVLDSLEEWTLYEVKMNACNDVGCSKESDTAVERTREAVPSY 1274

Query: 734  PPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTV-HQA 792
             P++++    ++TTV ++W     Q +NG I GY V        A++    ++ T+ + A
Sbjct: 1275 GPLDVQANATSSTTVVVQWGEVPRQHRNGQIDGYKVFY----AAADRGQQVLHKTIPNNA 1330

Query: 793  T-SLIMTNLTSGVSYSVQIAAETIIGLGPFS 822
            T +  +T L   V Y VQ+ A T +G G  S
Sbjct: 1331 TFTTTLTELKKYVVYHVQVLAYTRLGNGALS 1361



 Score = 50.8 bits (116), Expect = 2e-04
 Identities = 43/191 (22%), Positives = 82/191 (42%), Gaps = 14/191 (7%)

Query: 639  IEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITI---------EYEMKTILHSNDV 689
            ++A PI S  ++L+W+        G  + ++    +T          ++E +  + S   
Sbjct: 1686 VDAAPISSTEVRLLWKPPKQSMQNGDILGYKIYYLVTYSPQALEPGRKWEEEIEVVSATA 1745

Query: 690  SGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVH 749
            +   +  L K+T+Y   L+ F    +G  S     +TL  VP   P+++    +   ++ 
Sbjct: 1746 TSHSLVFLDKFTEYRIQLLAFNPAGDGPRSAPITVKTLPGVPSA-PLHLRFSDITMQSLE 1804

Query: 750  LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQ 809
            + W PP  +  NG I GY  +V +     N+            T+L + NL   V+Y+  
Sbjct: 1805 VTWDPP--KFLNGEILGY--LVTYETTEENEKFSKQVKQKVSNTTLRVQNLEEEVTYTFT 1860

Query: 810  IAAETIIGLGP 820
            + A+T +  GP
Sbjct: 1861 VRAQTSVDYGP 1871



 Score = 50.0 bits (114), Expect = 4e-04
 Identities = 35/131 (26%), Positives = 61/131 (46%), Gaps = 2/131 (1%)

Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSN-SRVAQTLDDVPDGPPINIEMFILNTTTVHLKW 752
           + +L+  T Y+F +    +  EG PS  S V +   + P GPP+       + + +  +W
Sbjct: 717 LENLKAATVYQFRVSAVNRVGEGSPSEPSNVVELPQEAPSGPPVGFVGSARSMSEIITQW 776

Query: 753 SPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAA 812
            PP  + +NG I GY ++   L    N      N T     + ++  L +   Y VQIAA
Sbjct: 777 QPPLEEHRNGQILGY-ILRYRLFGYNNVPWSYQNITNEAQRNFLIQELITWKDYIVQIAA 835

Query: 813 ETIIGLGPFSQ 823
              +G+G +++
Sbjct: 836 YNNMGVGVYTE 846



 Score = 41.5 bits (93), Expect = 0.14
 Identities = 32/138 (23%), Positives = 57/138 (41%), Gaps = 4/138 (2%)

Query: 684  LHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNS-RVAQTLDDVPDGPPINIEMFI 742
            ++  D     +T L  +T+Y   L         KPS + +  QT+   P  PP N+ +  
Sbjct: 1118 INDPDAETLTVTGLVPFTQYRLRLSASNVVGSSKPSEATKDFQTIQARPKHPPFNVTVRA 1177

Query: 743  LNTTTVHLKWSPPELQLQNGIITGYNVVVNWL-DVPANKSMVAINTTV--HQATSLIMTN 799
            ++   + ++W P +     G   GYN+    L   P     V  +  +  H A S ++ +
Sbjct: 1178 MSAQQLRVRWIPLQQTEWYGNPRGYNISYKQLVKTPGTIKYVPRSVVIEDHTANSHVLDS 1237

Query: 800  LTSGVSYSVQIAAETIIG 817
            L     Y V++ A   +G
Sbjct: 1238 LEEWTLYEVKMNACNDVG 1255



 Score = 41.1 bits (92), Expect = 0.18
 Identities = 34/97 (35%), Positives = 45/97 (46%), Gaps = 8/97 (8%)

Query: 14  IIEQPLDVTVARHQPATLNCRAGGSPSPA--IRWYKGG--VLVVSDTHRSILPAGGLFFL 69
           II+ P+D TV     ATL C+    PS    I WY+ G     +S++ R  + A G   +
Sbjct: 548 IIQPPVDTTVLLGLTATLQCKVSSDPSVPYNIDWYREGQSSTPISNSQRIGVQADGQLEI 607

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVL 106
           +A      SD G Y C  T S G   +R A L V  L
Sbjct: 608 QAVRA---SDVGSYACVVT-SPGGNETRAARLSVIEL 640



 Score = 37.1 bits (82), Expect = 2.9
 Identities = 33/139 (23%), Positives = 59/139 (42%), Gaps = 9/139 (6%)

Query: 689  VSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINI---EMFILNT 745
            +S F    LR Y  Y+F +        G  + SR +  +  +P  P + +   ++  + T
Sbjct: 1529 LSSFTAVGLRPYMTYQFRIQATNDL--GPSAFSRESVIVRTLPAAPAVGVGGLKVVPITT 1586

Query: 746  TTVHLKWSPPELQLQNGIIT--GYNVVVNWLDVPANKSMVAINTTVH--QATSLIMTNLT 801
            T+V ++WS  E  L NG  +  GY ++   L            T VH     S+++++L 
Sbjct: 1587 TSVRVQWSALETALWNGDASTGGYRILYQQLSDFPTALQSTPKTDVHGINENSVVLSDLQ 1646

Query: 802  SGVSYSVQIAAETIIGLGP 820
               +Y + +      G GP
Sbjct: 1647 QDRNYEIVVLPFNSQGPGP 1665



 Score = 36.3 bits (80), Expect = 5.1
 Identities = 43/199 (21%), Positives = 79/199 (39%), Gaps = 13/199 (6%)

Query: 639  IEATPIDSKTIKLMW-EILNFY---YLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEI 694
            ++A    S T+ + W E+   +    ++G  +++   D    +   KTI  +N      +
Sbjct: 1279 VQANATSSTTVVVQWGEVPRQHRNGQIDGYKVFYAAADRGQ-QVLHKTI-PNNATFTTTL 1336

Query: 695  TSLRKYTKYEFFLIPFYKKFEGKPSNSRV-AQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
            T L+KY  Y   ++ + +   G  S   +  QT +D P G P N+    ++ T   + W 
Sbjct: 1337 TELKKYVVYHVQVLAYTRLGNGALSTPPIRVQTFEDTP-GVPSNVSFPDVSLTMARIIWD 1395

Query: 754  PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAE 813
             P     NG I  Y V      +  +  +           +   T L  G  YS    A+
Sbjct: 1396 VP--VDPNGKILAYQVTYT---LNGSAMLNYSREFPPSDRTFRATELLPGKYYSFSCTAQ 1450

Query: 814  TIIGLGPFSQKVYFNIDSR 832
            T +G G  +  + +  ++R
Sbjct: 1451 TRLGWGKIATALVYTTNNR 1469


>UniRef50_UPI0000E47478 Cluster: PREDICTED: similar to hemicentin,
           partial; n=6; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to hemicentin, partial -
           Strongylocentrotus purpuratus
          Length = 1839

 Score =  138 bits (333), Expect = 1e-30
 Identities = 135/480 (28%), Positives = 196/480 (40%), Gaps = 42/480 (8%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTH-RSILPAGGLFFLR 70
           P I+EQP  VT  +  P TL CRA G+P PA  W K G L   D++ R+ L  G L    
Sbjct: 515 PSIVEQPESVTGDQRIPLTLTCRAIGTPEPAYYWEKDGALFDMDSNDRASLDGGNLVIES 574

Query: 71  ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC- 129
            T     +D G Y C A N               V+ +     P   Q +QG  + L C 
Sbjct: 575 LT----TADDGQYQCFANNR-------------LVMEQFENTAPAMVQLSQGQPLKLRCG 617

Query: 130 -LP--PRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA-RN 184
             P  P G+P P +YW   + +      ++R++    GNLV  +   +DA  Y C+A  N
Sbjct: 618 GSPGIPNGNPAPLIYWTDASPKHTSITYNARINQDLEGNLVFSNIIASDAKGYYCLAINN 677

Query: 185 AAGT-RESAIATLKIHIKP------YLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
             G  + S    L +   P      +L + P    VA    S   +C   G P P + W+
Sbjct: 678 VVGLFQRSPKIMLSVTDLPAVASAAHLDSHPAASEVANRTQSFKLKCIAFGYPTPVITWK 737

Query: 237 RSAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295
           R         GRV + + G +L +  V  +DEG Y+C A N+ G    S  +TV   P  
Sbjct: 738 RGEEQLQSG-GRVSIEESGQALVISAVENSDEGTYTCVASNTGGDDEFSTVVTVESAPYF 796

Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF-PGMSRDKYHATAVFDGVT 354
              P+      G      C + G P PT+ W V G     F   +  +++        + 
Sbjct: 797 LAPPSDKTKGPGESVDIECRSEGVPPPTVEWLVNGQTWADFESNIDTERWTVVTGDPQLA 856

Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--K 412
            + I +    DS N   C A N          L V S    P  I +  P  + L +   
Sbjct: 857 TIAITNLQTTDS-NVFQCIATNKYKEELTSVVLNVVS---FPARITSFTPLTRRLSVVED 912

Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT-NDGTLVLKDLDKSDSGTYTCVASS 471
             A F C +   P+P I W F+G  L    +  +   +G+LV+ ++ K D G Y C A +
Sbjct: 913 DSAKFICHSRGRPDPTITWTFKGSVLTNGIKYTINETEGSLVINNVKKVDGGEYECRAEN 972



 Score =  133 bits (322), Expect = 2e-29
 Identities = 135/502 (26%), Positives = 205/502 (40%), Gaps = 46/502 (9%)

Query: 4    DYVTSGEAPYIIEQPLDVTVA-RHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
            D      A ++   P    VA R Q   L C A G P+P I W +G   + S    SI  
Sbjct: 694  DLPAVASAAHLDSHPAASEVANRTQSFKLKCIAFGYPTPVITWKRGEEQLQSGGRVSIEE 753

Query: 63   AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122
            +G    + A     +SD G Y C A+N+ G      +T+        F   P  K    G
Sbjct: 754  SGQALVISAVE---NSDEGTYTCVASNTGGD--DEFSTVVTVESAPYFLAPPSDKTKGPG 808

Query: 123  DTVVLECLPPRGSPEPNVYWKKNGQTLL-FDGD---SRMHLVDG----GNLVIQDARQTD 174
            ++V +EC    G P P V W  NGQT   F+ +    R  +V G      + I + + TD
Sbjct: 809  ESVDIECRS-EGVPPPTVEWLVNGQTWADFESNIDTERWTVVTGDPQLATIAITNLQTTD 867

Query: 175  AGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTG----SSVTFQCRVGGDPL 230
            +  +QCIA N     E     L +   P  IT    +  +       S  F C   G P 
Sbjct: 868  SNVFQCIATNKY-KEELTSVVLNVVSFPARITSFTPLTRRLSVVEDDSAKFICHSRGRPD 926

Query: 231  PDVLWRRSAGGGNMPLGRVKVLDD--GSLRLDNVILADEGEYSCEAENSVGA----VSAS 284
            P + W  +  G  +  G    +++  GSL ++NV   D GEY C AEN++       + S
Sbjct: 927  PTITW--TFKGSVLTNGIKYTINETEGSLVINNVKKVDGGEYECRAENAIDGEDYEATGS 984

Query: 285  GYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP---EPTMFWSVEGNRTIIFPGMSR 341
              LT+    +I LSP ++ +  GN A F C  T      EP ++W  +G R      +  
Sbjct: 985  ATLTMLGKTTIYLSPANLMIREGNTATFQCEITYDEELIEPYVYWMKDGQR------LEA 1038

Query: 342  DKYHATAVFDGVTVL-TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR----- 395
            +++  +     +  L  +  +   +S +  +  A+  AG   +  +    + D R     
Sbjct: 1039 NQFLDSGGVRFMRCLPPLATSASRESISRSIVEAIQAAGPEGLLPEGRTRAHDTRRYIGY 1098

Query: 396  --PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTL 452
               PP I   P +     +      C A  TPEP   W  +G    + ++ R   + G L
Sbjct: 1099 NDVPPSIVEQPESINGDQRVPLTLTCRATGTPEPTYYWEKDGALFNVDSNDRVSLDGGNL 1158

Query: 453  VLKDLDKSDSGTYTCVASSRHG 474
            V+K L  +D G Y C A +R G
Sbjct: 1159 VIKSLTTADDGQYQCFAKNRLG 1180



 Score =  105 bits (251), Expect = 1e-20
 Identities = 129/462 (27%), Positives = 187/462 (40%), Gaps = 48/462 (10%)

Query: 38   SPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
            SP+P I W +G   + S    SI        + A     +SD G Y C A+NS G     
Sbjct: 1290 SPTPVITWKRGEEQLQSGGRVSIHEHE--LVISAVE---NSDEGTYTCVASNSGGD--DE 1342

Query: 98   NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL-FDGD-- 154
             +T+        F   P  +    G++V +EC    G P P V W  NGQ    F+ +  
Sbjct: 1343 FSTVVTVESAPYFPYPPSDESKRPGESVDIEC-RSEGVPAPTVDWFVNGQPWADFESNRD 1401

Query: 155  -SRMHLVDG----GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK---PYLIT 206
              R  +V G      + I + + TD+  +QCIA N      +++      I    P    
Sbjct: 1402 TERWEVVTGDPQLATISITNLQTTDSNVFQCIATNMYKEELTSVVLNVFSIPASIPSFTP 1461

Query: 207  GPEDVVAQTGSSVTFQCRVGG-----------DPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
                +      S  F C V G           DP P + W+R         GRV + + G
Sbjct: 1462 LTRKLSVVQNDSAKFTCHVEGRPLPIIKISVLDPTPVITWKRGEEQLQSG-GRVSIQEFG 1520

Query: 256  -SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV-YD-PPSINLSPNSVNVESGNVARF 312
              L +    ++DEG Y+C A N+ G    S  +TV YD PPSI   P S+N +       
Sbjct: 1521 QELVIFAFEISDEGTYTCVASNTGGDDEFSTVVTVEYDVPPSIVEQPESINGDERIPLTL 1580

Query: 313  TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
            TC ATG PEPT +W  +G    +F   S D+       DG  ++  + T  +D +    C
Sbjct: 1581 TCRATGTPEPTYYWEKDG---ALFNVDSNDR----VSLDGGNLVIESLTTADDGQ--YQC 1631

Query: 373  SAVNYAGSSFVRGKLTVTSDDDRPPPI-ITNGPSNQTLPIK-SMAVFPCTAICTPEPIIA 430
             A N  G++  +  LT  +  D+   I       +Q  P+K      P     TP P+I 
Sbjct: 1632 FAKNRLGTAMSQKILTSLAFMDQFENIEPARIQVSQGQPLKLRCGGSPGVPNGTPAPLIY 1691

Query: 431  WYF---EGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
            W     +   +  N R N    G LV  ++  SD+  Y C A
Sbjct: 1692 WTDATPKPTPITYNARINQDPQGNLVFSNVIASDAKGYYCQA 1733



 Score =  105 bits (251), Expect = 1e-20
 Identities = 105/414 (25%), Positives = 172/414 (41%), Gaps = 41/414 (9%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-----DTHRSI 60
            VT   APY    P D +    +   + CR+ G P+P + W+  G          DT R  
Sbjct: 1347 VTVESAPYFPYPPSDESKRPGESVDIECRSEGVPAPTVDWFVNGQPWADFESNRDTERWE 1406

Query: 61   LPAGG--LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEF-RLEPESK 117
            +  G   L  +  T+ +  +D+ V+ C ATN Y    + +  L+V  +        P ++
Sbjct: 1407 VVTGDPQLATISITNLQT-TDSNVFQCIATNMYKEELT-SVVLNVFSIPASIPSFTPLTR 1464

Query: 118  QSA--QGDTVVLEC------LPPRG----SPEPNVYWKKNGQTLLFDGDSRMHLVD-GGN 164
            + +  Q D+    C      LP        P P + WK+  + L   G  R+ + + G  
Sbjct: 1465 KLSVVQNDSAKFTCHVEGRPLPIIKISVLDPTPVITWKRGEEQLQSGG--RVSIQEFGQE 1522

Query: 165  LVIQDARQTDAGRYQCIARNAAGTRE-SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223
            LVI     +D G Y C+A N  G  E S + T++  + P ++  PE +       +T  C
Sbjct: 1523 LVIFAFEISDEGTYTCVASNTGGDDEFSTVVTVEYDVPPSIVEQPESINGDERIPLTLTC 1582

Query: 224  RVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSA 283
            R  G P P   W +     N+       LD G+L ++++  AD+G+Y C A+N +G   +
Sbjct: 1583 RATGTPEPTYYWEKDGALFNVDSNDRVSLDGGNLVIESLTTADDGQYQCFAKNRLGTAMS 1642

Query: 284  SGYLT--VYDPPSINLSPNSVNVESGNVARFTC-----TATGRPEPTMFWSVEGNRTIIF 336
               LT   +     N+ P  + V  G   +  C        G P P ++W      T   
Sbjct: 1643 QKILTSLAFMDQFENIEPARIQVSQGQPLKLRCGGSPGVPNGTPAPLIYW------TDAT 1696

Query: 337  PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV-NYAGSSFVRGKLTV 389
            P  +   Y+A    D    L  ++   +D++    C A+ N  GSS    K+T+
Sbjct: 1697 PKPTPITYNARINQDPQGNLVFSNVIASDAKG-YYCQAINNVVGSSQRSPKVTL 1749



 Score =  104 bits (250), Expect = 1e-20
 Identities = 136/503 (27%), Positives = 200/503 (39%), Gaps = 64/503 (12%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P I+EQP  +   +  P TL CRA G+P P   W K G L   D++  +   GG   +++
Sbjct: 1103 PSIVEQPESINGDQRVPLTLTCRATGTPEPTYYWEKDGALFNVDSNDRVSLDGGNLVIKS 1162

Query: 72   THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC-- 129
                  +D G Y C A N  GTA S+     +A + +    EP   Q  +G  + L C  
Sbjct: 1163 L---TTADDGQYQCFAKNRLGTAMSQKILTSLAFMDQFENTEPAWIQVRRGRPLKLLCGG 1219

Query: 130  LP--PRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA-RNA 185
             P  P G+P P +YW     +      ++R+     GNLV   A  +DA  Y C A  N 
Sbjct: 1220 SPGIPNGNPAPLIYWTNAAAKPTPITYNARIAQDPEGNLVFSHAIASDAQGYYCQAINNI 1279

Query: 186  AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
             G+ +           P  I  P  V+  T      Q + GG        R S     + 
Sbjct: 1280 VGSSQRT---------P--IISPTPVI--TWKRGEEQLQSGG--------RVSIHEHELV 1318

Query: 246  LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP-NSVNV 304
            +  V+  D+G+          + E+S     +V  V ++ Y   Y P   +  P  SV++
Sbjct: 1319 ISAVENSDEGTYTCVASNSGGDDEFS-----TVVTVESAPYFP-YPPSDESKRPGESVDI 1372

Query: 305  ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD-K 363
            E        C + G P PT+ W V G     F   +RD      V     + TI+ T+ +
Sbjct: 1373 E--------CRSEGVPAPTVDWFVNGQPWADFES-NRDTERWEVVTGDPQLATISITNLQ 1423

Query: 364  NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPC-- 419
                N   C A N          L V S    P  I +  P  + L +     A F C  
Sbjct: 1424 TTDSNVFQCIATNMYKEELTSVVLNVFS---IPASIPSFTPLTRKLSVVQNDSAKFTCHV 1480

Query: 420  ---------TAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVA 469
                      ++  P P+I W    E L    R ++   G  LV+   + SD GTYTCVA
Sbjct: 1481 EGRPLPIIKISVLDPTPVITWKRGEEQLQSGGRVSIQEFGQELVIFAFEISDEGTYTCVA 1540

Query: 470  SSRHGKYVWSGALLVDSPINPNI 492
            S+  G   +S  + V+  + P+I
Sbjct: 1541 SNTGGDDEFSTVVTVEYDVPPSI 1563



 Score = 99.5 bits (237), Expect = 5e-19
 Identities = 95/357 (26%), Positives = 145/357 (40%), Gaps = 25/357 (7%)

Query: 135  SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194
            SP P + WK+  + L   G   +H  +   LVI     +D G Y C+A N+ G  E +  
Sbjct: 1290 SPTPVITWKRGEEQLQSGGRVSIHEHE---LVISAVENSDEGTYTCVASNSGGDDEFS-T 1345

Query: 195  TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-----GNMPLGRV 249
             + +   PY    P D   + G SV  +CR  G P P V W  +         N    R 
Sbjct: 1346 VVTVESAPYFPYPPSDESKRPGESVDIECRSEGVPAPTVDWFVNGQPWADFESNRDTERW 1405

Query: 250  KVLDD----GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSI-NLSP--NS 301
            +V+       ++ + N+   D   + C A N       S  L V+  P SI + +P    
Sbjct: 1406 EVVTGDPQLATISITNLQTTDSNVFQCIATNMYKEELTSVVLNVFSIPASIPSFTPLTRK 1465

Query: 302  VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHA---TAVFDGVTVLTI 358
            ++V   + A+FTC   GRP P +  SV     +I      ++  +    ++ +    L I
Sbjct: 1466 LSVVQNDSAKFTCHVEGRPLPIIKISVLDPTPVITWKRGEEQLQSGGRVSIQEFGQELVI 1525

Query: 359  NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
               + +D   T  C A N  G       +TV  D    PP I   P +     +      
Sbjct: 1526 FAFEISDE-GTYTCVASNTGGDDEFSTVVTVEYD---VPPSIVEQPESINGDERIPLTLT 1581

Query: 419  CTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
            C A  TPEP   W  +G    + ++ R   + G LV++ L  +D G Y C A +R G
Sbjct: 1582 CRATGTPEPTYYWEKDGALFNVDSNDRVSLDGGNLVIESLTTADDGQYQCFAKNRLG 1638



 Score = 94.7 bits (225), Expect = 1e-17
 Identities = 90/329 (27%), Positives = 129/329 (39%), Gaps = 34/329 (10%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLR 70
           P I+EQP  +   +  P TL CRA G P P   W K G L  V    R+ L  G L    
Sbjct: 32  PSIVEQPESINGDQRIPLTLTCRATGIPEPTYYWEKDGSLFDVDSNDRASLDGGNLVIES 91

Query: 71  ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC- 129
            T     +D G Y C A N     +  N                E+ Q  QG  + L C 
Sbjct: 92  LT----TADDGQYQCFANNRLVMDQFENTAW-------------ETIQVDQGRPLKLRCG 134

Query: 130 -LP--PRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN- 184
             P  P G+P P +YW     +      ++R+     G+LV  +   +DA  Y C A N 
Sbjct: 135 GSPGVPNGNPAPLMYWTDAAAKPTPISYNARISQDPEGSLVFSNVIASDAKGYYCQAINN 194

Query: 185 -AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVT-------FQCRVGGDPLPDVLWR 236
               +++S   TL +   P + +G   V     S +         +C   G P P++ W+
Sbjct: 195 VVGSSQQSPKVTLMVSDLPAVDSGASLVTKPAASEIAIRTQSFKLKCIAYGYPTPEITWK 254

Query: 237 RSAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295
           R         GR+ + + G  L +  V  +D+G Y+C A N  G    S  +TV   P  
Sbjct: 255 RGEEQLQSG-GRISIEESGQELVISTVENSDKGTYTCVASNCEGIDEFSTVVTVESAPYF 313

Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTM 324
              P+      G      C + G P PT+
Sbjct: 314 PAPPSDETKRPGESVDIECRSKGVPAPTL 342



 Score = 92.7 bits (220), Expect = 6e-17
 Identities = 110/451 (24%), Positives = 178/451 (39%), Gaps = 56/451 (12%)

Query: 113 EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ 172
           +PES    Q   + L C    G+PEP  YW+K+G     D + R  L DGGNLVI+    
Sbjct: 520 QPESVTGDQRIPLTLTCRAI-GTPEPAYYWEKDGALFDMDSNDRASL-DGGNLVIESLTT 577

Query: 173 TDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR-----VGG 227
            D G+YQC A N            ++ ++ +  T P  V    G  +  +C        G
Sbjct: 578 ADDGQYQCFANN------------RLVMEQFENTAPAMVQLSQGQPLKLRCGGSPGIPNG 625

Query: 228 DPLPDVLWRRSAGGGNMPLGRVKVLDD--GSLRLDNVILADEGEYSCEAENSVGAV---S 282
           +P P + W  ++          ++  D  G+L   N+I +D   Y C A N+V  +   S
Sbjct: 626 NPAPLIYWTDASPKHTSITYNARINQDLEGNLVFSNIIASDAKGYYCLAINNVVGLFQRS 685

Query: 283 ASGYLTVYDPPSI----NLSPNSVNVESGNVA---RFTCTATGRPEPTMFWSVEGNRTII 335
               L+V D P++    +L  +    E  N     +  C A G P P + W   G   + 
Sbjct: 686 PKIMLSVTDLPAVASAAHLDSHPAASEVANRTQSFKLKCIAFGYPTPVITWK-RGEEQLQ 744

Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395
             G         ++ +    L I+  + +D   T  C A N  G       +TV S    
Sbjct: 745 SGGR-------VSIEESGQALVISAVENSDE-GTYTCVASNTGGDDEFSTVVTVES---- 792

Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG------EALIQNHRRNV-TN 448
             P     PS++T          C +   P P + W   G      E+ I   R  V T 
Sbjct: 793 -APYFLAPPSDKTKGPGESVDIECRSEGVPPPTVEWLVNGQTWADFESNIDTERWTVVTG 851

Query: 449 D---GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL-LVDSPINPNIHFFRAADVSSLP 504
           D    T+ + +L  +DS  + C+A++++ + + S  L +V  P            +S + 
Sbjct: 852 DPQLATIAITNLQTTDSNVFQCIATNKYKEELTSVVLNVVSFPARITSFTPLTRRLSVVE 911

Query: 505 GPPTKPITHNVTDTSVTLSWSQNNKIGSSSI 535
               K I H+      T++W+    + ++ I
Sbjct: 912 DDSAKFICHSRGRPDPTITWTFKGSVLTNGI 942



 Score = 88.2 bits (209), Expect = 1e-15
 Identities = 60/196 (30%), Positives = 90/196 (45%), Gaps = 10/196 (5%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P I+EQP  +      P TL CRA G+P P   W K G L   D++  +   GG   + +
Sbjct: 1561 PSIVEQPESINGDERIPLTLTCRATGTPEPTYYWEKDGALFNVDSNDRVSLDGGNLVIES 1620

Query: 72   THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC-- 129
                  +D G Y C A N  GTA S+     +A + +   +EP   Q +QG  + L C  
Sbjct: 1621 L---TTADDGQYQCFAKNRLGTAMSQKILTSLAFMDQFENIEPARIQVSQGQPLKLRCGG 1677

Query: 130  LP--PRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN-- 184
             P  P G+P P +YW     +      ++R++    GNLV  +   +DA  Y C A N  
Sbjct: 1678 SPGVPNGTPAPLIYWTDATPKPTPITYNARINQDPQGNLVFSNVIASDAKGYYCQAINNV 1737

Query: 185  AAGTRESAIATLKIHI 200
               ++ S   TL++ +
Sbjct: 1738 VGSSQRSPKVTLRVRV 1753



 Score = 87.0 bits (206), Expect = 3e-15
 Identities = 102/379 (26%), Positives = 153/379 (40%), Gaps = 59/379 (15%)

Query: 113 EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ 172
           +PES    Q   + L C    G PEP  YW+K+G     D + R  L DGGNLVI+    
Sbjct: 37  QPESINGDQRIPLTLTCRAT-GIPEPTYYWEKDGSLFDVDSNDRASL-DGGNLVIESLTT 94

Query: 173 TDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR-----VGG 227
            D G+YQC A N            ++ +  +  T  E +    G  +  +C        G
Sbjct: 95  ADDGQYQCFANN------------RLVMDQFENTAWETIQVDQGRPLKLRCGGSPGVPNG 142

Query: 228 DPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEA-ENSVGAVSA 283
           +P P + W   A     P+    R+    +GSL   NVI +D   Y C+A  N VG+   
Sbjct: 143 NPAPLMYW-TDAAAKPTPISYNARISQDPEGSLVFSNVIASDAKGYYCQAINNVVGSSQQ 201

Query: 284 SGYLT--VYDPPSINLSPNSVNVESGN-VA------RFTCTATGRPEPTMFWSVEGNRTI 334
           S  +T  V D P+++   + V   + + +A      +  C A G P P + W   G   +
Sbjct: 202 SPKVTLMVSDLPAVDSGASLVTKPAASEIAIRTQSFKLKCIAYGYPTPEITWK-RGEEQL 260

Query: 335 IFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394
              G         ++ +    L I+ T +N  + T  C A N  G       +TV S   
Sbjct: 261 QSGG-------RISIEESGQELVIS-TVENSDKGTYTCVASNCEGIDEFSTVVTVESAPY 312

Query: 395 RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN--DGTL 452
            P P     PS++T          C +   P P +           N  +   N  +G+L
Sbjct: 313 FPAP-----PSDETKRPGESVDIECRSKGVPAPTLT----------NRDKYTVNETEGSL 357

Query: 453 VLKDLDKSDSGTYTCVASS 471
           V+ ++ K DSG Y C A +
Sbjct: 358 VINNVKKVDSGEYECRAEN 376



 Score = 85.8 bits (203), Expect = 6e-15
 Identities = 79/305 (25%), Positives = 130/305 (42%), Gaps = 32/305 (10%)

Query: 195 TLKIH-IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD 253
           T+ IH + P ++  PE +       +T  CR  G P P   W +     ++       LD
Sbjct: 24  TVPIHDVPPSIVEQPESINGDQRIPLTLTCRATGIPEPTYYWEKDGSLFDVDSNDRASLD 83

Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313
            G+L ++++  AD+G+Y C A N +          V D    N +  ++ V+ G   +  
Sbjct: 84  GGNLVIESLTTADDGQYQCFANNRL----------VMDQFE-NTAWETIQVDQGRPLKLR 132

Query: 314 CTAT-----GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
           C  +     G P P M+W+    +           Y+A    D    L  ++   +D++ 
Sbjct: 133 CGGSPGVPNGNPAPLMYWTDAAAKPTPI------SYNARISQDPEGSLVFSNVIASDAKG 186

Query: 369 TIVCSAVN-YAGSSFVRGKLTVTSDD----DRPPPIITNGPSNQTLPIKSMAV-FPCTAI 422
              C A+N   GSS    K+T+   D    D    ++T  P+   + I++ +    C A 
Sbjct: 187 -YYCQAINNVVGSSQQSPKVTLMVSDLPAVDSGASLVTK-PAASEIAIRTQSFKLKCIAY 244

Query: 423 CTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
             P P I W    E L    R ++   G  LV+  ++ SD GTYTCVAS+  G   +S  
Sbjct: 245 GYPTPEITWKRGEEQLQSGGRISIEESGQELVISTVENSDKGTYTCVASNCEGIDEFSTV 304

Query: 482 LLVDS 486
           + V+S
Sbjct: 305 VTVES 309



 Score = 83.8 bits (198), Expect = 3e-14
 Identities = 76/275 (27%), Positives = 118/275 (42%), Gaps = 34/275 (12%)

Query: 21  VTVARHQPATLNCRAG-----GSPSPAIRWYKGGVLVVSDTHRSIL---PAGGLFFLRAT 72
           + V + +P  L C        G+P+P + W          ++ + +   P G L F    
Sbjct: 121 IQVDQGRPLKLRCGGSPGVPNGNPAPLMYWTDAAAKPTPISYNARISQDPEGSLVFSNV- 179

Query: 73  HGRVHSDAGVYWCEATNSY--GTARSRNATLHVAVLRE-----EFRLEPESKQSA-QGDT 124
              + SDA  Y+C+A N+    + +S   TL V+ L           +P + + A +  +
Sbjct: 180 ---IASDAKGYYCQAINNVVGSSQQSPKVTLMVSDLPAVDSGASLVTKPAASEIAIRTQS 236

Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIAR 183
             L+C+   G P P + WK+  + L   G  R+ + + G  LVI     +D G Y C+A 
Sbjct: 237 FKLKCIA-YGYPTPEITWKRGEEQLQSGG--RISIEESGQELVISTVENSDKGTYTCVAS 293

Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
           N  G  E +   + +   PY    P D   + G SV  +CR  G P P  L  R     N
Sbjct: 294 NCEGIDEFS-TVVTVESAPYFPAPPSDETKRPGESVDIECRSKGVPAP-TLTNRDKYTVN 351

Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSV 278
                     +GSL ++NV   D GEY C AEN++
Sbjct: 352 ET--------EGSLVINNVKKVDSGEYECRAENAI 378



 Score = 83.8 bits (198), Expect = 3e-14
 Identities = 76/303 (25%), Positives = 124/303 (40%), Gaps = 29/303 (9%)

Query: 195 TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254
           TL     P ++  PE V       +T  CR  G P P   W +     +M       LD 
Sbjct: 508 TLLDDFPPSIVEQPESVTGDQRIPLTLTCRAIGTPEPAYYWEKDGALFDMDSNDRASLDG 567

Query: 255 GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
           G+L ++++  AD+G+Y C A N +        +  ++    N +P  V +  G   +  C
Sbjct: 568 GNLVIESLTTADDGQYQCFANNRL-------VMEQFE----NTAPAMVQLSQGQPLKLRC 616

Query: 315 TAT-----GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
             +     G P P ++W      T   P  +   Y+A    D    L  ++   +D++  
Sbjct: 617 GGSPGIPNGNPAPLIYW------TDASPKHTSITYNARINQDLEGNLVFSNIIASDAKG- 669

Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPI----ITNGPSNQTLPIKSMAV-FPCTAICT 424
             C A+N     F R    + S  D P       + + P+   +  ++ +    C A   
Sbjct: 670 YYCLAINNVVGLFQRSPKIMLSVTDLPAVASAAHLDSHPAASEVANRTQSFKLKCIAFGY 729

Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
           P P+I W    E L    R ++   G  LV+  ++ SD GTYTCVAS+  G   +S  + 
Sbjct: 730 PTPVITWKRGEEQLQSGGRVSIEESGQALVISAVENSDEGTYTCVASNTGGDDEFSTVVT 789

Query: 484 VDS 486
           V+S
Sbjct: 790 VES 792



 Score = 77.8 bits (183), Expect = 2e-12
 Identities = 82/337 (24%), Positives = 126/337 (37%), Gaps = 38/337 (11%)

Query: 21   VTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
            ++V     A   C + G P P I W +KG VL     +      G L            D
Sbjct: 907  LSVVEDDSAKFICHSRGRPDPTITWTFKGSVLTNGIKYTINETEGSLVINNVKK----VD 962

Query: 80   AGVYWCEATNSY-GTARSRNATLHVAVL-REEFRLEPESKQSAQGDTVVLECLPPRGSP- 136
             G Y C A N+  G       +  + +L +    L P +    +G+T   +C        
Sbjct: 963  GGEYECRAENAIDGEDYEATGSATLTMLGKTTIYLSPANLMIREGNTATFQCEITYDEEL 1022

Query: 137  -EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ-------DARQTDAGRYQCIARNAAGT 188
             EP VYW K+GQ L    ++   L  GG   ++        A +    R    A  AAG 
Sbjct: 1023 IEPYVYWMKDGQRL----EANQFLDSGGVRFMRCLPPLATSASRESISRSIVEAIQAAGP 1078

Query: 189  -------RESAIATLKI----HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
                   R  A  T +      + P ++  PE +       +T  CR  G P P   W +
Sbjct: 1079 EGLLPEGRTRAHDTRRYIGYNDVPPSIVEQPESINGDQRVPLTLTCRATGTPEPTYYWEK 1138

Query: 238  SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT--VYDPPSI 295
                 N+       LD G+L + ++  AD+G+Y C A+N +G   +   LT   +     
Sbjct: 1139 DGALFNVDSNDRVSLDGGNLVIKSLTTADDGQYQCFAKNRLGTAMSQKILTSLAFMDQFE 1198

Query: 296  NLSPNSVNVESGNVARFTCTAT-----GRPEPTMFWS 327
            N  P  + V  G   +  C  +     G P P ++W+
Sbjct: 1199 NTEPAWIQVRRGRPLKLLCGGSPGIPNGNPAPLIYWT 1235


>UniRef50_Q8C310-3 Cluster: Isoform 3 of Q8C310 ; n=2; Murinae|Rep:
           Isoform 3 of Q8C310 - Mus musculus (Mouse)
          Length = 1057

 Score =  138 bits (333), Expect = 1e-30
 Identities = 82/209 (39%), Positives = 113/209 (54%), Gaps = 18/209 (8%)

Query: 5   YVTSGEA----PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSDTH 57
           ++  GEA    P I+  P D  +    PA + CR+ G P P IRW   G    +   D H
Sbjct: 21  FIMGGEALDSPPQILVHPQDQLLQGSGPAKMRCRSSGQPPPTIRWLLNGQPLSMATPDLH 80

Query: 58  RSILPAGGLFFLR-ATHGRVHSDA-------GVYWCEATNSYGTARSRNATLHVAVLREE 109
             +LP G L   R +  GR   D        GVY CEA+N  GTA SR A L VAVL+E+
Sbjct: 81  Y-LLPDGTLLLHRPSVQGRPQDDQNILSAILGVYTCEASNRLGTAVSRGARLSVAVLQED 139

Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
           F+++P    +  G+++VLEC PP G P+P+V W K+G+ L+     R   V G +L++  
Sbjct: 140 FQIQPRDTVAVVGESLVLECGPPWGYPKPSVSWWKDGKPLVLQPGRR--TVSGDSLMVSR 197

Query: 170 ARQTDAGRYQCIARNAAGTRESAIATLKI 198
           A + D+G Y C+A N AG RES  A + I
Sbjct: 198 AEKNDSGTYMCMATNNAGQRESRAARVSI 226



 Score = 60.5 bits (140), Expect = 3e-07
 Identities = 48/192 (25%), Positives = 90/192 (46%), Gaps = 14/192 (7%)

Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR-TIIFPGMSRDKYHATAVF 350
           PP I + P    ++    A+  C ++G+P PT+ W + G   ++  P +       T + 
Sbjct: 31  PPQILVHPQDQLLQGSGPAKMRCRSSGQPPPTIRWLLNGQPLSMATPDLHYLLPDGTLLL 90

Query: 351 DGVTVLTINDTDKNDSRNTI---VCSAVNYAGSSFVRG---KLTVTSDDDRPPPIITNGP 404
              +V      D+N     +    C A N  G++  RG    + V  +D +  P  T   
Sbjct: 91  HRPSVQGRPQDDQNILSAILGVYTCEASNRLGTAVSRGARLSVAVLQEDFQIQPRDTVAV 150

Query: 405 SNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI-QNHRRNVTNDGTLVLKDLDKSDSG 463
             ++L ++    +       P+P ++W+ +G+ L+ Q  RR V+ D  +V +  +K+DSG
Sbjct: 151 VGESLVLECGPPWGY-----PKPSVSWWKDGKPLVLQPGRRTVSGDSLMVSR-AEKNDSG 204

Query: 464 TYTCVASSRHGK 475
           TY C+A++  G+
Sbjct: 205 TYMCMATNNAGQ 216



 Score = 57.2 bits (132), Expect = 3e-06
 Identities = 43/124 (34%), Positives = 59/124 (47%), Gaps = 8/124 (6%)

Query: 703 YEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNG 762
           YEF + P   +  G  SN  + +  + VP  PP  + +   N + V + W+PP  +  NG
Sbjct: 320 YEFKVRPSSGRARGPDSNVLLLRLPEQVPSAPPQGVTLRSGNGS-VFVSWAPPPAESHNG 378

Query: 763 IITGYNVVVNWLDVPANKSMVAIN-TTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPF 821
           +I GY V   W     N S+ A N T V + T L +     G SY VQ+AA T  G G  
Sbjct: 379 VIRGYQV---W--SLGNASLPAANWTVVGEQTQLEIATRLPG-SYCVQVAAVTGAGAGEL 432

Query: 822 SQKV 825
           S  V
Sbjct: 433 STPV 436



 Score = 54.8 bits (126), Expect = 1e-05
 Identities = 53/194 (27%), Positives = 80/194 (41%), Gaps = 26/194 (13%)

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK-VLDDGSLRL- 259
           P ++  P+D + Q       +CR  G P P + W  +    +M    +  +L DG+L L 
Sbjct: 32  PQILVHPQDQLLQGSGPAKMRCRSSGQPPPTIRWLLNGQPLSMATPDLHYLLPDGTLLLH 91

Query: 260 -----------DNVILADEGEYSCEAENSVG-AVSASGYLTV-YDPPSINLSPNSVNVES 306
                       N++ A  G Y+CEA N +G AVS    L+V        + P       
Sbjct: 92  RPSVQGRPQDDQNILSAILGVYTCEASNRLGTAVSRGARLSVAVLQEDFQIQPRDTVAVV 151

Query: 307 GNVARFTC-TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
           G      C    G P+P++ W  +G   ++ PG        T   D    L ++  +KND
Sbjct: 152 GESLVLECGPPWGYPKPSVSWWKDGKPLVLQPG------RRTVSGDS---LMVSRAEKND 202

Query: 366 SRNTIVCSAVNYAG 379
           S  T +C A N AG
Sbjct: 203 S-GTYMCMATNNAG 215



 Score = 35.5 bits (78), Expect = 8.9
 Identities = 32/104 (30%), Positives = 44/104 (42%), Gaps = 15/104 (14%)

Query: 394 DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN--HRRNVTNDGT 451
           D PP I+ + P +Q L     A   C +   P P I W   G+ L         +  DGT
Sbjct: 29  DSPPQILVH-PQDQLLQGSGPAKMRCRSSGQPPPTIRWLLNGQPLSMATPDLHYLLPDGT 87

Query: 452 LVL------------KDLDKSDSGTYTCVASSRHGKYVWSGALL 483
           L+L            +++  +  G YTC AS+R G  V  GA L
Sbjct: 88  LLLHRPSVQGRPQDDQNILSAILGVYTCEASNRLGTAVSRGARL 131


>UniRef50_UPI0000F33D9D Cluster: Perlecan; n=1; Bos taurus|Rep:
            Perlecan - Bos Taurus
          Length = 3005

 Score =  137 bits (331), Expect = 2e-30
 Identities = 147/525 (28%), Positives = 209/525 (39%), Gaps = 67/525 (12%)

Query: 9    GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVS-DTHRSILPAGGL 66
            G AP I  +     VA  Q   L C   G     + W++ GG L     TH S L     
Sbjct: 1879 GGAPPIRIETSSSHVAEGQTLDLKCVVPGQAHAQVTWHRRGGSLPARHQTHGSRL----- 1933

Query: 67   FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
                  H    SD+G Y C      G+ +  + T+ V +      ++P S    QG    
Sbjct: 1934 ----RLHHVSQSDSGEYVCRVVGGSGSEQEASFTITVRLRSPVISIDPPSSTVQQGQDAS 1989

Query: 127  LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNA 185
             +CL   G+   ++ WK   Q L    +  + +   G+++ I  AR ++ G Y+C+A NA
Sbjct: 1990 FKCLVHDGAAPISLEWKTRNQEL----EDNVRISPNGSIITIVGARPSNHGAYRCVASNA 2045

Query: 186  AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
             G  +S +  L +H  PY  T PE    + G +V  QC   G P     W R   GG++P
Sbjct: 2046 YGVAQS-VVNLSVHGPPYATTVPEHASVRAGEAVQLQCLAHGTPPLTFQWSRV--GGHLP 2102

Query: 246  LGRVKVLDDGSLRLDNVILADEGEYSCEAEN--------SVGAV---------SASGYLT 288
             G      +  L  +     D G Y C+  N        SV  V          AS +L 
Sbjct: 2103 AG--ATARNELLLFEAAAPEDSGRYRCQVTNRHREGLQSSVAHVLLLLKASGQPASPHLL 2160

Query: 289  VYDP--PS--INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
               P  PS  IN+  +  +V  G+   F C A G P+P + WS  G R  + PG+ +   
Sbjct: 2161 PSSPALPSVLINIRTSVQSVVVGHAVEFECLALGDPKPQVTWSKVGGR--LRPGIVQSG- 2217

Query: 345  HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404
                    V +  +   D    R    C+A N AG++     L V +     P I T  P
Sbjct: 2218 ------GIVRIARVELADAGQYR----CTATNAAGTTQSHVLLLVQA----LPQIST--P 2261

Query: 405  SNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGT 464
                +P  S AVFPC     P P I W      L  + R     +  L+L  +   D+GT
Sbjct: 2262 PEVRVPAGSTAVFPCMVSGYPAPEITWSKLDGNLPPDSR---LENHMLLLPSVQPQDAGT 2318

Query: 465  YTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTK 509
            Y C A++R GK      L V   + P   +F     S LP P  K
Sbjct: 2319 YVCTATNRQGKVKAFAQLQVPERVVP---YFTQTPYSFLPLPTIK 2360



 Score =  109 bits (261), Expect = 6e-22
 Identities = 135/513 (26%), Positives = 200/513 (38%), Gaps = 54/513 (10%)

Query: 11   APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWY--KGGVL-VVSDTHRSILPAGGLF 67
            AP +   P  +TV   Q A   C A G P P++ W    GG L   +  HR IL      
Sbjct: 1402 APVVSIHPPQLTVQPGQMAEFRCSATGHPMPSLEWTGGPGGQLPQKAQVHRGILR----- 1456

Query: 68   FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV-AVLREEFRLEPESKQSAQGDTVV 126
             L A      SD G Y C A +S G   +R A LHV        ++ PE  Q  +G TV 
Sbjct: 1457 -LPAVEA---SDQGQYLCRAHSSAGQHVAR-AVLHVHGGNGPRVQVSPERTQVHEGRTVR 1511

Query: 127  LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
            L C    G P   + W+K G +L     +R    D   L+I      DAG Y C+A + A
Sbjct: 1512 LYC-RAAGVPSATITWRKEGGSL--PPQARAERTDIATLLIPAITAADAGFYLCVATSPA 1568

Query: 187  GTRESAIATLKIHIKPYLITGPEDVVAQT-----GSSVTFQCRVGGDPLPDVLWRRSAGG 241
            GT   A A +++ + P   T P  + + +     G ++   C V G     + W +  GG
Sbjct: 1569 GT---AQARIQVVVLPGATTPPVRIESSSPSVTEGQTLDLNCVVAGLAHSQITWYK-RGG 1624

Query: 242  GNMPLGRVKVLDDGSLR-LDNVILADEGEYSCEAENSVGAVSASGYLTV--YDPPSINLS 298
               P  +V+    GSL  +     AD GEY C  EN  G   AS  ++V     P + + 
Sbjct: 1625 SLPPHAQVR----GSLSPVVGAPRADSGEYVCRVENDSGPKEASIIVSVPPGPVPPVRIE 1680

Query: 299  PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
             +S  V  G      C   G+    + W   G      P   +       V  G  +   
Sbjct: 1681 SSSPTVAEGQTLDLNCVVAGQAHAPVTWYKRGG---TLPARHQ-------VPGGRKIFQA 1730

Query: 359  NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-F 417
            +  D  +     VC A N   +S     +TVT         +T   +N+    +   +  
Sbjct: 1731 SPADAGE----YVCRASNGVEASIT---VTVTKTQGANFAYLTPKNNNKAKVAEGQTLDL 1783

Query: 418  PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
             C     P   + W+  G +L   H+ +  ++  L +  +  +DSG Y C  S+  G   
Sbjct: 1784 NCLVSGQPHAQVTWHKRGGSLPARHQLHSESE-LLRIPQVTPADSGEYVCHVSNGAGSQE 1842

Query: 478  WSGALLVDSPINPNIHFFRAADVSSLPGPPTKP 510
             S  L+V    + + H    A+ +  P   T P
Sbjct: 1843 TS--LIVTIQGSDSSHAGAGAEGARSPSSLTSP 1873



 Score = 97.9 bits (233), Expect = 1e-18
 Identities = 121/486 (24%), Positives = 181/486 (37%), Gaps = 46/486 (9%)

Query: 5    YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
            +V  G  P +   P    V   +   L CRA G PS  I W K G  +            
Sbjct: 1486 HVHGGNGPRVQVSPERTQVHEGRTVRLYCRAAGVPSATITWRKEGGSLPPQARAERTDIA 1545

Query: 65   GLFFLRATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGD 123
             L     T     +DAG Y C AT+  GTA++R    +         R+E  S    +G 
Sbjct: 1546 TLLIPAIT----AADAGFYLCVATSPAGTAQARIQVVVLPGATTPPVRIESSSPSVTEGQ 1601

Query: 124  TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
            T+ L C+   G     + W K G +L      R     G    +  A + D+G Y C   
Sbjct: 1602 TLDLNCV-VAGLAHSQITWYKRGGSLPPHAQVR-----GSLSPVVGAPRADSGEYVCRVE 1655

Query: 184  NAAGTRESAI--ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
            N +G +E++I  +     + P  I      VA+ G ++   C V G     V W +   G
Sbjct: 1656 NDSGPKEASIIVSVPPGPVPPVRIESSSPTVAE-GQTLDLNCVVAGQAHAPVTWYKR--G 1712

Query: 242  GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN---LS 298
            G +P  R +V   G  ++     AD GEY C A N    V AS  +TV      N   L+
Sbjct: 1713 GTLP-ARHQV--PGGRKIFQASPADAGEYVCRASN---GVEASITVTVTKTQGANFAYLT 1766

Query: 299  P---NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY-----HATAVF 350
            P   N   V  G      C  +G+P   + W   G        +  +         T   
Sbjct: 1767 PKNNNKAKVAEGQTLDLNCLVSGQPHAQVTWHKRGGSLPARHQLHSESELLRIPQVTPAD 1826

Query: 351  DGVTVLTINDTDKNDSRNTIVC-----SAVNYAGSSFVRGKLTVTSD----DDRPPPIIT 401
             G  V  +++   +   + IV      S+   AG+   R   ++TS         PPI  
Sbjct: 1827 SGEYVCHVSNGAGSQETSLIVTIQGSDSSHAGAGAEGARSPSSLTSPCGPAPGGAPPIRI 1886

Query: 402  NGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSD 461
               S+     +++ +  C         + W+  G +L   H+   T+   L L  + +SD
Sbjct: 1887 ETSSSHVAEGQTLDL-KCVVPGQAHAQVTWHRRGGSLPARHQ---THGSRLRLHHVSQSD 1942

Query: 462  SGTYTC 467
            SG Y C
Sbjct: 1943 SGEYVC 1948



 Score = 93.9 bits (223), Expect = 2e-17
 Identities = 101/393 (25%), Positives = 147/393 (37%), Gaps = 40/393 (10%)

Query: 111  RLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA 170
            ++ P      QG    L C    GSP    YW +     L     + H   G  L     
Sbjct: 1308 QVHPTRSVVPQGGPHSLRC-QVSGSPPHYFYWSREDGRPLPSSTQQRH--QGSELHFPSV 1364

Query: 171  RQTDAGRYQCIARN---AAGTRESAIAT----LKIHIKPYLITGPEDVVAQTGSSVTFQC 223
            + +DAG Y C  RN   A  +R   + T          P +   P  +  Q G    F+C
Sbjct: 1365 QPSDAGVYICTCRNLHHANTSRAELLVTDPSPSATPSAPVVSIHPPQLTVQPGQMAEFRC 1424

Query: 224  RVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSA 283
               G P+P + W    GG    L +   +  G LRL  V  +D+G+Y C A +S G   A
Sbjct: 1425 SATGHPMPSLEWTGGPGG---QLPQKAQVHRGILRLPAVEASDQGQYLCRAHSSAGQHVA 1481

Query: 284  SGYLTVY--DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341
               L V+  + P + +SP    V  G   R  C A G P  T+ W  EG      P  +R
Sbjct: 1482 RAVLHVHGGNGPRVQVSPERTQVHEGRTVRLYCRAAGVPSATITWRKEGGS---LPPQAR 1538

Query: 342  DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP-PII 400
                  A    +  L I      D+    +C A + AG++  R ++ V      PP  I 
Sbjct: 1539 ------AERTDIATLLIPAITAADA-GFYLCVATSPAGTAQARIQVVVLPGATTPPVRIE 1591

Query: 401  TNGPS---NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL 457
            ++ PS    QTL +       C         I WY  G +L  + +          +   
Sbjct: 1592 SSSPSVTEGQTLDLN------CVVAGLAHSQITWYKRGGSLPPHAQ---VRGSLSPVVGA 1642

Query: 458  DKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
             ++DSG Y C   +  G      +++V  P  P
Sbjct: 1643 PRADSGEYVCRVENDSGPK--EASIIVSVPPGP 1673



 Score = 81.0 bits (191), Expect = 2e-13
 Identities = 80/333 (24%), Positives = 120/333 (36%), Gaps = 23/333 (6%)

Query: 10   EAPYIIE-QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
            +AP +++  P    V +  P +L C+  GSP     W +     +  + +       L F
Sbjct: 1302 QAPLVVQVHPTRSVVPQGGPHSLRCQVSGSPPHYFYWSREDGRPLPSSTQQRHQGSELHF 1361

Query: 69   LRATHGRVHSDAGVYWCEATNSYGTARSRNATL------HVAVLREEFRLEPESKQSAQG 122
                     SDAGVY C   N +    SR   L                + P       G
Sbjct: 1362 PSVQP----SDAGVYICTCRNLHHANTSRAELLVTDPSPSATPSAPVVSIHPPQLTVQPG 1417

Query: 123  DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
                  C    G P P++ W   G        +++H    G L +     +D G+Y C A
Sbjct: 1418 QMAEFRC-SATGHPMPSLEW-TGGPGGQLPQKAQVH---RGILRLPAVEASDQGQYLCRA 1472

Query: 183  RNAAGTRESAIATLKIH--IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
             ++AG +  A A L +H    P +   PE      G +V   CR  G P   + WR+  G
Sbjct: 1473 HSSAG-QHVARAVLHVHGGNGPRVQVSPERTQVHEGRTVRLYCRAAGVPSATITWRKE-G 1530

Query: 241  GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---DPPSINL 297
            G   P  R +  D  +L +  +  AD G Y C A +  G   A   + V      P + +
Sbjct: 1531 GSLPPQARAERTDIATLLIPAITAADAGFYLCVATSPAGTAQARIQVVVLPGATTPPVRI 1590

Query: 298  SPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
              +S +V  G      C   G     + W   G
Sbjct: 1591 ESSSPSVTEGQTLDLNCVVAGLAHSQITWYKRG 1623



 Score = 52.8 bits (121), Expect = 5e-05
 Identities = 50/204 (24%), Positives = 81/204 (39%), Gaps = 15/204 (7%)

Query: 292  PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
            P  + + P    V  G      C  +G P    +WS E  R +  P  ++ ++  +    
Sbjct: 1304 PLVVQVHPTRSVVPQGGPHSLRCQVSGSPPHYFYWSREDGRPL--PSSTQQRHQGSE--- 1358

Query: 352  GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT--SDDDRPP-PIITNGPSNQT 408
                L       +D+    +C+  N   ++  R +L VT  S    P  P+++  P   T
Sbjct: 1359 ----LHFPSVQPSDA-GVYICTCRNLHHANTSRAELLVTDPSPSATPSAPVVSIHPPQLT 1413

Query: 409  LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468
            +    MA F C+A   P P + W   G    Q  ++   + G L L  ++ SD G Y C 
Sbjct: 1414 VQPGQMAEFRCSATGHPMPSLEW--TGGPGGQLPQKAQVHRGILRLPAVEASDQGQYLCR 1471

Query: 469  ASSRHGKYVWSGALLVDSPINPNI 492
            A S  G++V    L V     P +
Sbjct: 1472 AHSSAGQHVARAVLHVHGGNGPRV 1495



 Score = 51.6 bits (118), Expect = 1e-04
 Identities = 32/85 (37%), Positives = 50/85 (58%), Gaps = 7/85 (8%)

Query: 202 PYLITGPEDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDG---S 256
           P ++T P++++ A  G +VTF C   G P P + WR +   G++P   RV V  +G   +
Sbjct: 122 PQVVTPPQELIQASRGQTVTFTCVAIGVPTPIINWRLN--WGHIPSHPRVTVTSEGGRGT 179

Query: 257 LRLDNVILADEGEYSCEAENSVGAV 281
           L + +V  AD+G Y+CEA N+ G V
Sbjct: 180 LTIHDVKEADQGAYTCEAMNARGMV 204



 Score = 48.4 bits (110), Expect = 0.001
 Identities = 35/116 (30%), Positives = 50/116 (43%), Gaps = 8/116 (6%)

Query: 397 PPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TL 452
           PP +   P       +   V F C AI  P PII W      +  + R  VT++G   TL
Sbjct: 121 PPQVVTPPQELIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTL 180

Query: 453 VLKDLDKSDSGTYTCVASSRHGKY--VWSGA--LLVDSPINPNIHFFRAADVSSLP 504
            + D+ ++D G YTC A +  G    +  G   L+      P+ HF+     S LP
Sbjct: 181 TIHDVKEADQGAYTCEAMNARGMVFGIPDGVLELIPQRGPCPDGHFYLEHSASCLP 236



 Score = 41.5 bits (93), Expect = 0.14
 Identities = 25/82 (30%), Positives = 36/82 (43%), Gaps = 2/82 (2%)

Query: 12  PYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
           P ++  P + +  +R Q  T  C A G P+P I W      + S    ++   GG   L 
Sbjct: 122 PQVVTPPQELIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTL- 180

Query: 71  ATHGRVHSDAGVYWCEATNSYG 92
             H    +D G Y CEA N+ G
Sbjct: 181 TIHDVKEADQGAYTCEAMNARG 202



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 2/71 (2%)

Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAG 176
           Q+++G TV   C+   G P P + W+ N   +       +    G G L I D ++ D G
Sbjct: 133 QASRGQTVTFTCVAI-GVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLTIHDVKEADQG 191

Query: 177 RYQCIARNAAG 187
            Y C A NA G
Sbjct: 192 AYTCEAMNARG 202


>UniRef50_Q4RVM0 Cluster: Chromosome 9 SCAF14991, whole genome
           shotgun sequence; n=8; Euteleostomi|Rep: Chromosome 9
           SCAF14991, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 478

 Score =  136 bits (330), Expect = 3e-30
 Identities = 132/434 (30%), Positives = 181/434 (41%), Gaps = 38/434 (8%)

Query: 32  NCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
           +C A G P+P  RW      +      R  L  G L   R        D GVY C A+NS
Sbjct: 43  SCEAQGHPAPFYRWKLNDSFIHPRPGSRYSLMGGNLHISRLNKDE---DVGVYQCLASNS 99

Query: 91  YGTARSRNATLHVAVLREEFRLEPESK-QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
           +GT  SR A+LHVA L E+F+    S  +  +G  VVL C PP  S E    W  N    
Sbjct: 100 FGTIVSREASLHVAYL-EDFKTHRRSPVRVREGQGVVLLCGPPPHSGELTFTWIFNEYPS 158

Query: 150 LFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGTRESAIA-----TLKI----- 198
               D+R  +    GNL I     +D G Y C+  N   T+ S         L++     
Sbjct: 159 FVTQDTRRFVSQKTGNLYIAKVVPSDVGNYTCVVTNTV-TKSSVQGPPTPLVLRVDGVMG 217

Query: 199 HIKPYL-ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD--DG 255
             +P + +  PE V     S+VT +C   G+P+P + WRR+ G      GR   ++   G
Sbjct: 218 EYEPKIEVQFPEVVPVAKSSTVTLECFALGNPVPTISWRRADGAS---FGRKVDVNKASG 274

Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315
            L +    + D G Y C AENS G  S  G L+ Y  P ++  P  V         + C 
Sbjct: 275 VLEIPYFQIEDAGMYECVAENSRGRNSVKGKLSFYAAPQLSEKPQDVQKTIDETLVWECK 334

Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
           A+ +P+P+  W   G           D+     V +G  VLTI+  +  D      C A 
Sbjct: 335 ASAKPKPSYRWLKNGEPL----DHMEDRLQ---VNNG--VLTISSLNLADI-GMYQCVAE 384

Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFE 434
           N  G  F   +L V +     P    N    QTL  +   V   C    +P  II+W   
Sbjct: 385 NRHGRVFTNAELRVIA---IAPDFSQNLLKAQTLTRQGGDVLIECKPRMSPRGIISWRKG 441

Query: 435 GEALIQNHRRNVTN 448
            EAL +NHR  + N
Sbjct: 442 KEALRENHRPELQN 455



 Score =  102 bits (244), Expect = 7e-20
 Identities = 101/376 (26%), Positives = 147/376 (39%), Gaps = 33/376 (8%)

Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA-RQTDAGRYQCIAR 183
           VV  C   +G P P   WK N   +     SR  L+ GGNL I    +  D G YQC+A 
Sbjct: 40  VVFSC-EAQGHPAPFYRWKLNDSFIHPRPGSRYSLM-GGNLHISRLNKDEDVGVYQCLAS 97

Query: 184 NAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRV---GGDPLPDVLWRRSA 239
           N+ GT  S  A+L + +++ +       V  + G  V   C      G+     ++    
Sbjct: 98  NSFGTIVSREASLHVAYLEDFKTHRRSPVRVREGQGVVLLCGPPPHSGELTFTWIFNEYP 157

Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV---------- 289
                   R      G+L +  V+ +D G Y+C   N+V   S  G  T           
Sbjct: 158 SFVTQDTRRFVSQKTGNLYIAKVVPSDVGNYTCVVTNTVTKSSVQGPPTPLVLRVDGVMG 217

Query: 290 -YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
            Y+P      P  V V   +     C A G P PT+ W      +    G   D   A+ 
Sbjct: 218 EYEPKIEVQFPEVVPVAKSSTVTLECFALGNPVPTISWRRADGASF---GRKVDVNKASG 274

Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408
           V + +    I D    +      C A N  G + V+GKL+  +      P ++  P +  
Sbjct: 275 VLE-IPYFQIEDAGMYE------CVAENSRGRNSVKGKLSFYA-----APQLSEKPQDVQ 322

Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468
             I    V+ C A   P+P   W   GE L     R   N+G L +  L+ +D G Y CV
Sbjct: 323 KTIDETLVWECKASAKPKPSYRWLKNGEPLDHMEDRLQVNNGVLTISSLNLADIGMYQCV 382

Query: 469 ASSRHGKYVWSGALLV 484
           A +RHG+   +  L V
Sbjct: 383 AENRHGRVFTNAELRV 398



 Score = 71.3 bits (167), Expect = 1e-10
 Identities = 62/225 (27%), Positives = 92/225 (40%), Gaps = 11/225 (4%)

Query: 15  IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74
           ++ P  V VA+    TL C A G+P P I W +            +  A G+  L   + 
Sbjct: 225 VQFPEVVPVAKSSTVTLECFALGNPVPTISWRRADGASFG-RKVDVNKASGV--LEIPYF 281

Query: 75  RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRG 134
           ++  DAG+Y C A NS G    +      A    +   +P+  Q    +T+V EC     
Sbjct: 282 QI-EDAGMYECVAENSRGRNSVKGKLSFYAA--PQLSEKPQDVQKTIDETLVWEC-KASA 337

Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194
            P+P+  W KNG+ L    D R+  V+ G L I      D G YQC+A N  G   +   
Sbjct: 338 KPKPSYRWLKNGEPLDHMED-RLQ-VNNGVLTISSLNLADIGMYQCVAENRHGRVFTNAE 395

Query: 195 TLKIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
              I I P           + + G  V  +C+    P   + WR+
Sbjct: 396 LRVIAIAPDFSQNLLKAQTLTRQGGDVLIECKPRMSPRGIISWRK 440



 Score = 57.6 bits (133), Expect = 2e-06
 Identities = 40/141 (28%), Positives = 63/141 (44%), Gaps = 8/141 (5%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
           AP + E+P DV     +     C+A   P P+ RW K G   +      +    G+  + 
Sbjct: 311 APQLSEKPQDVQKTIDETLVWECKASAKPKPSYRWLKNGE-PLDHMEDRLQVNNGVLTIS 369

Query: 71  ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEF--RLEPESKQSAQGDTVVLE 128
           + +    +D G+Y C A N +G   + NA L V  +  +F   L      + QG  V++E
Sbjct: 370 SLN---LADIGMYQCVAENRHGRVFT-NAELRVIAIAPDFSQNLLKAQTLTRQGGDVLIE 425

Query: 129 CLPPRGSPEPNVYWKKNGQTL 149
           C  PR SP   + W+K  + L
Sbjct: 426 C-KPRMSPRGIISWRKGKEAL 445


>UniRef50_A2AT18 Cluster: Titin; n=11; Eukaryota|Rep: Titin - Mus
            musculus (Mouse)
          Length = 8268

 Score =  136 bits (329), Expect = 3e-30
 Identities = 128/504 (25%), Positives = 195/504 (38%), Gaps = 25/504 (4%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            ++P+   +P+ + V   + A   C   G+    + W K    +    + +I   G    L
Sbjct: 2930 KSPFFDIKPVSIDVIAGESADFECHVTGAQPMRVTWSKDNKEIRPGGNYTITCVGNTPHL 2989

Query: 70   RATH-GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
            R    G+   D+G Y C+ATN  G     +A L V    +  +    SK + QG+++ LE
Sbjct: 2990 RILKVGK--GDSGQYTCQATNDVGKDMC-SAQLSVKEPPKFIKKLDASKVAKQGESIQLE 3046

Query: 129  CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAG 187
            C    GSPE  V W +N   L       M  V+    L I +A   D G Y C A N  G
Sbjct: 3047 C-KISGSPEIKVVWFRNDSELHESWKYNMSFVNSVALLTINEASAEDTGDYICEAHNGVG 3105

Query: 188  TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW--RRSAGGGNMP 245
                + A LK+   P     P  V A  GS V  QC + G P  +V+W   R     +  
Sbjct: 3106 DASCSTA-LKVKAPPVFTQKPPPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRSSKK 3164

Query: 246  LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
                    D SL + N+   D GEY C+A N VG+ + +  +   +PP      +  +  
Sbjct: 3165 FKITSKNFDTSLHIFNLEAPDIGEYHCKATNEVGSDTCACTVKFKEPPRFVKKLSDASTL 3224

Query: 306  SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF-DGVTVLTINDTDKN 364
             G+         G    ++ W  +    I      R+  +    F D +  L +   + +
Sbjct: 3225 IGDPVELQAVVEGFQPISVVWLKDKGEVI------RESENVRISFVDNIATLQLGSPEAS 3278

Query: 365  DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
             S    VC   N AG       LTV       P  I   P   T+   +     C    T
Sbjct: 3279 QS-GKYVCQIKNDAGMRECSAVLTVLE-----PATIVEKPEPMTVTTGNPFTLECVVAGT 3332

Query: 425  PEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
            PE    W+ +G  L    R ++T   N  +L +   + +D G YT    +R GK   + +
Sbjct: 3333 PELSAKWFKDGRELSSGSRHHITFVRNLASLKIPSAEMNDKGLYTFEVENRVGKSSCTVS 3392

Query: 482  LLVDSPINPNIHFFRAADVSSLPG 505
            + V   + P     R  D S+  G
Sbjct: 3393 VHVSDRVVPPSFVRRLKDTSATLG 3416



 Score =  136 bits (328), Expect = 5e-30
 Identities = 137/527 (25%), Positives = 207/527 (39%), Gaps = 31/527 (5%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            E PY IE    V  A  +P TL C+  G+P   I WYK    + S     +     +  L
Sbjct: 3679 EPPYFIEPLEHVEAAIGEPITLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASL 3738

Query: 70   RATHGRVHSDAGVYWCEATNSYGT-ARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
               +   HSD G Y C+A NS G  A S    +    L   F  + +      G  V  E
Sbjct: 3739 -VINKVDHSDVGEYTCKAENSVGAVASSAVLVIKERKLPPSFARKLKDVHETLGFPVAFE 3797

Query: 129  CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAG 187
            C    GS    V W K+G+ L  D + +M  V     L I    Q+  G+Y C A N  G
Sbjct: 3798 CRI-NGSEPLQVSWYKDGELLKDDANLQMSFVHHVATLQILQTDQSHVGQYNCSASNPLG 3856

Query: 188  TRES-AIATLKIH-IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGG 241
            T  S A   L  H + P+    P  V    G S +F+C V G     + W    R    G
Sbjct: 3857 TASSSAKLILSEHEVPPFFDLKPVSVDLALGESGSFKCHVTGTAPIKITWAKDNREIRPG 3916

Query: 242  GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS-INLSPN 300
            GN  +  V+  +  +L +  V   D G+Y+C A N  G  S S  L V +PP  I     
Sbjct: 3917 GNYKMTLVE--NTATLTVLKVAKGDAGQYTCYASNVAGKDSCSAQLGVQEPPRFIKKLDQ 3974

Query: 301  SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
            S  V+     R+ C   G PE  + W  +         +        +  D V +L ++ 
Sbjct: 3975 SRIVKQDEYTRYECKIGGSPEIKVLWYKDEVE------IQESSKFRMSFEDSVAILEMHS 4028

Query: 361  TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
                DS     C A N AGS+     L V     + PP+    P        +     C 
Sbjct: 4029 LSVEDS-GDYTCEARNAAGSASSSTSLKV-----KEPPVFRKKPFPVETLKGADVHLECE 4082

Query: 421  AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLV---LKDLDKSDSGTYTCVASSRHGKYV 477
               TP   ++W+ +   L    +  + ++  L    + ++D +D G Y C A++  G   
Sbjct: 4083 LQGTPPFQVSWHKDKRELRSGKKYKIMSENLLTSIHILNVDTADIGEYQCKATNDVGSDT 4142

Query: 478  WSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSW 524
              G++ + +P  P     +  D+S++ G   +  T       ++++W
Sbjct: 4143 CVGSVTMKAP--PQF-VKKLTDISTIIGKEVQLQTTIEGAEPISVAW 4186



 Score =  133 bits (321), Expect = 3e-29
 Identities = 134/521 (25%), Positives = 213/521 (40%), Gaps = 35/521 (6%)

Query: 3    DDYVTSGEAPYIIEQ--PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI 60
            D  V++ E PY + +  PL+ +V      +L C+  G+P   + W+KG   + S      
Sbjct: 2731 DALVSTLEPPYFVTELEPLEASVG--DSVSLQCQVAGTPEITVSWFKGDTKLRSTPEYRT 2788

Query: 61   LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNA-TLHVAVLREEFRLEPESKQS 119
                 +  L      + +D+G Y C A NS GTA S+    +    L   F  + +  + 
Sbjct: 2789 YFTNNVATLVFNKVSI-NDSGEYTCMAENSIGTAASKTIFRIQERQLPPSFARQLKDIEQ 2847

Query: 120  AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRY 178
              G  V L C    GS    V W ++G  L  D + +M  VD    L I     + +G+Y
Sbjct: 2848 TVGLPVTLTC-RLNGSAPIQVCWYRDGVLLRDDENLQMSFVDNVATLKILQTDLSHSGQY 2906

Query: 179  QCIARNAAGTRESA--IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
             C A N  GT  S   +   +    P+    P  +    G S  F+C V G     V W 
Sbjct: 2907 SCSASNPLGTASSTARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRVTWS 2966

Query: 237  RS----AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
            +       GGN  +    V +   LR+  V   D G+Y+C+A N VG    S  L+V +P
Sbjct: 2967 KDNKEIRPGGNYTI--TCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEP 3024

Query: 293  PS-INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
            P  I     S   + G   +  C  +G PE  + W    N + +       KY+ + V +
Sbjct: 3025 PKFIKKLDASKVAKQGESIQLECKISGSPEIKVVWF--RNDSELHESW---KYNMSFV-N 3078

Query: 352  GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
             V +LTIN+    D+    +C A N  G +     L V     + PP+ T  P       
Sbjct: 3079 SVALLTINEASAEDT-GDYICEAHNGVGDASCSTALKV-----KAPPVFTQKPPPVGALK 3132

Query: 412  KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN---DGTLVLKDLDKSDSGTYTCV 468
             S  +  C    TP   + W  + + +  + +  +T+   D +L + +L+  D G Y C 
Sbjct: 3133 GSDVILQCEISGTPPFEVVWVKDRKQVRSSKKFKITSKNFDTSLHIFNLEAPDIGEYHCK 3192

Query: 469  ASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTK 509
            A++  G    +  +    P  P     + +D S+L G P +
Sbjct: 3193 ATNEVGSDTCACTVKFKEP--PRF-VKKLSDASTLIGDPVE 3230



 Score =  130 bits (314), Expect = 2e-28
 Identities = 114/465 (24%), Positives = 192/465 (41%), Gaps = 27/465 (5%)

Query: 33   CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
            C+ GGSP   + WYK  V +   +   +     +  L   H     D+G Y CEA N+ G
Sbjct: 3988 CKIGGSPEIKVLWYKDEVEIQESSKFRMSFEDSVAILEM-HSLSVEDSGDYTCEARNAAG 4046

Query: 93   TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFD 152
            +A S + +L V      FR +P   ++ +G  V LEC   +G+P   V W K+ + L   
Sbjct: 4047 SASS-STSLKVKE-PPVFRKKPFPVETLKGADVHLEC-ELQGTPPFQVSWHKDKRELR-- 4101

Query: 153  GDSRMHLVDGGNLV----IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208
               + + +   NL+    I +    D G YQC A N  G+ ++ + ++ +   P  +   
Sbjct: 4102 -SGKKYKIMSENLLTSIHILNVDTADIGEYQCKATNDVGS-DTCVGSVTMKAPPQFVKKL 4159

Query: 209  EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL---DDGSLRLDNVILA 265
             D+    G  V  Q  + G     V W +  G        + +    +  +L+      A
Sbjct: 4160 TDISTIIGKEVQLQTTIEGAEPISVAWFKDKGEIVRESDNIWISYSENIATLQFSRAEPA 4219

Query: 266  DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325
            + G+Y+C+ +N  G       L+V +P +I   P S+ V +G+     CT +G PE +  
Sbjct: 4220 NAGKYTCQIKNDAGMQECYATLSVLEPAAIVEKPESIKVTTGDTCTLECTVSGTPELSTK 4279

Query: 326  WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385
            W  +G        ++ D  +  + F+ V+ L I +    DS         N  G      
Sbjct: 4280 WFKDGKE------LTSDNKYKISFFNKVSGLKIINVVPGDS-GVYSFEVQNPVGKDSC-- 4330

Query: 386  KLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN 445
            K+++   D   PP  T           S  V  C    +P   + W+ +G  +    +  
Sbjct: 4331 KVSIQVSDRIIPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVLWFHDGNEISSGRKYQ 4390

Query: 446  VT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
             T   N   L +  L+++D+G YTC+A++  G    S  L V  P
Sbjct: 4391 TTLTDNTCALTVNMLEEADAGDYTCIATNVAGSDECSAPLTVREP 4435



 Score =  128 bits (310), Expect = 7e-28
 Identities = 131/496 (26%), Positives = 206/496 (41%), Gaps = 25/496 (5%)

Query: 2    SDDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL 61
            S   +T  E P   + P  V V      T      G+P   ++W+KG   +VS    +I 
Sbjct: 3485 SSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVSGEACTIS 3544

Query: 62   PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
                +  L          +G Y C  TN  G+A   + T H+ V      ++  +  S +
Sbjct: 3545 LEDFVTELELLEVEP-GQSGDYSCLVTNDAGSA---SCTTHLFVKEPATFVKRLADTSVE 3600

Query: 122  -GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQ 179
             G  +VLE     G+P  +V W KN   L    +  +   +  +++ I ++   D  +Y 
Sbjct: 3601 TGSPIVLEATYS-GTPPISVSWMKNEYPLSQSPNCGITTTEKSSILEILESTIEDYAQYA 3659

Query: 180  CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW-RRS 238
            C+  N AG ++   A + +   PY I   E V A  G  +T QC+V G P   + W +  
Sbjct: 3660 CLIENEAG-QDICEALVSVLEPPYFIEPLEHVEAAIGEPITLQCKVDGTPEIRISWYKEH 3718

Query: 239  AGGGNMPLGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPS 294
                + P  +++  ++  SL ++ V  +D GEY+C+AENSVGAV++S  L + +   PPS
Sbjct: 3719 TKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYTCKAENSVGAVASSAVLVIKERKLPPS 3778

Query: 295  INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
                   V+   G    F C   G     + W  +G        +  D     +    V 
Sbjct: 3779 FARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGEL------LKDDANLQMSFVHHVA 3832

Query: 355  VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
             L I  TD++       CSA N  G++    KL ++  +   PP     P +  L +   
Sbjct: 3833 TLQILQTDQSHV-GQYNCSASNPLGTASSSAKLILS--EHEVPPFFDLKPVSVDLALGES 3889

Query: 415  AVFPCTAICTPEPIIAWYFEGEALIQ--NHRRN-VTNDGTLVLKDLDKSDSGTYTCVASS 471
              F C    T    I W  +   +    N++   V N  TL +  + K D+G YTC AS+
Sbjct: 3890 GSFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVAKGDAGQYTCYASN 3949

Query: 472  RHGKYVWSGALLVDSP 487
              GK   S  L V  P
Sbjct: 3950 VAGKDSCSAQLGVQEP 3965



 Score =  126 bits (304), Expect = 4e-27
 Identities = 132/495 (26%), Positives = 216/495 (43%), Gaps = 33/495 (6%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAG 64
            VT    P  +++  D++    +   L     G+   ++ W+K  G +V    +  I  + 
Sbjct: 4147 VTMKAPPQFVKKLTDISTIIGKEVQLQTTIEGAEPISVAWFKDKGEIVRESDNIWISYSE 4206

Query: 65   GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGD 123
             +  L+ +     ++AG Y C+  N  G      ATL  +VL     +E PES +   GD
Sbjct: 4207 NIATLQFSRAEP-ANAGKYTCQIKNDAGMQECY-ATL--SVLEPAAIVEKPESIKVTTGD 4262

Query: 124  TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIA 182
            T  LEC    G+PE +  W K+G+ L  D   ++   +    L I +    D+G Y    
Sbjct: 4263 TCTLECTVS-GTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVVPGDSGVYSFEV 4321

Query: 183  RNAAGTRESAIATLKIH---IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
            +N  G ++S   ++++    I P      ++    +GSSV  +C+V G P   VLW    
Sbjct: 4322 QNPVG-KDSCKVSIQVSDRIIPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVLWFHD- 4379

Query: 240  GGGNMPLGRV--KVLDDGSLRLDNVIL--ADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295
             G  +  GR     L D +  L   +L  AD G+Y+C A N  G+   S  LTV +PPS 
Sbjct: 4380 -GNEISSGRKYQTTLTDNTCALTVNMLEEADAGDYTCIATNVAGSDECSAPLTVREPPSF 4438

Query: 296  NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
               P+ ++V +G+   FT    G P  T+ W  +G+ T + PG   +     ++ D V  
Sbjct: 4439 VQKPDPMDVLTGSNVTFTSIVKGSPPFTVSW-FKGS-TELVPGARCN----VSLQDSVGE 4492

Query: 356  LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
            L + D D + S     C   N AG +    +L V     + P I     ++ ++      
Sbjct: 4493 LELFDVDTSQS-GEYTCIVSNEAGRASCTTRLFV-----KAPAIFVKRLNDYSIEKGKPL 4546

Query: 416  VFPCTAICTPEPIIAWYFEGEALIQNHRRNV-TNDGTLVLKDLDKS--DSGTYTCVASSR 472
            +   T   TP   + W   G  +I + R N+ T + + +L+ L  +  DSG Y C   + 
Sbjct: 4547 ILEGTFSGTPPISVTWKKNGINVIASQRCNITTTEKSAILEILSSTVEDSGQYNCYIENA 4606

Query: 473  HGKYVWSGALLVDSP 487
             GK   S  +L+  P
Sbjct: 4607 SGKDSCSAQILILEP 4621



 Score =  121 bits (291), Expect = 1e-25
 Identities = 123/507 (24%), Positives = 200/507 (39%), Gaps = 24/507 (4%)

Query: 31   LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
            + C+  GSP  ++ W+  G  + S              L   +    +DAG Y C ATN 
Sbjct: 4362 MECKVYGSPPISVLWFHDGNEISSGRKYQTTLTDNTCAL-TVNMLEEADAGDYTCIATNV 4420

Query: 91   YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
             G+    +A L V      F  +P+      G  V    +  +GSP   V W K    L+
Sbjct: 4421 AGSDEC-SAPLTVRE-PPSFVQKPDPMDVLTGSNVTFTSIV-KGSPPFTVSWFKGSTELV 4477

Query: 151  FDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
                  + L D  G L + D   + +G Y CI  N AG R S    L +      +    
Sbjct: 4478 PGARCNVSLQDSVGELELFDVDTSQSGEYTCIVSNEAG-RASCTTRLFVKAPAIFVKRLN 4536

Query: 210  DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD---DGSLRLDNVILAD 266
            D   + G  +  +    G P   V W+++ G   +   R  +        L + +  + D
Sbjct: 4537 DYSIEKGKPLILEGTFSGTPPISVTWKKN-GINVIASQRCNITTTEKSAILEILSSTVED 4595

Query: 267  EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326
             G+Y+C  EN+ G  S S  + + +PP        V V  G+ A   C   G PE  + W
Sbjct: 4596 SGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVTVGDSASLQCQLAGTPEIGVSW 4655

Query: 327  SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
              +G+ T + P  +  K H     + V  L     D +DS    +C A N  G   V   
Sbjct: 4656 -YKGD-TKLRP-TATCKMHFK---NNVATLVFTQVDSSDS-GEYICRAENSVGE--VSSS 4706

Query: 387  LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGEALIQNHRRN 445
              +T  + + PP  +    +    +    VF C A+   EPI ++WY +G+ L  +    
Sbjct: 4707 TFLTVQEQKLPPSFSRQLRDVQETVGLPVVFEC-AVSGSEPISVSWYKDGKPLKDSPNIQ 4765

Query: 446  VT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSS 502
             +   N  TL +   D+S SG Y+C A++  G       L++    NP       A + +
Sbjct: 4766 TSFLDNIATLNIFKTDRSLSGQYSCTATNPIGSASSGAKLILTEGKNPPFFDIPLAPMDA 4825

Query: 503  LPGPPTKPITHNVTDTSVTLSWSQNNK 529
            + G       H      + ++W+++N+
Sbjct: 4826 VVGESADLECHVTGTQPIKVTWAKDNR 4852



 Score =  120 bits (289), Expect = 2e-25
 Identities = 124/529 (23%), Positives = 210/529 (39%), Gaps = 28/529 (5%)

Query: 10   EAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
            +AP I  + L D ++ + +P  L     G+P  ++ W K G+ V++    +I        
Sbjct: 4526 KAPAIFVKRLNDYSIEKGKPLILEGTFSGTPPISVTWKKNGINVIASQRCNITTTEKSAI 4585

Query: 69   LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVL 127
            L      V  D+G Y C   N+ G     + +  + +L   + ++  E  +   GD+  L
Sbjct: 4586 LEILSSTVE-DSGQYNCYIENASG---KDSCSAQILILEPPYFVKQLEPVKVTVGDSASL 4641

Query: 128  ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAA 186
            +C    G+PE  V W K    L      +MH  +    LV      +D+G Y C A N+ 
Sbjct: 4642 QC-QLAGTPEIGVSWYKGDTKLRPTATCKMHFKNNVATLVFTQVDSSDSGEYICRAENSV 4700

Query: 187  GTRESA--IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GN 243
            G   S+  +   +  + P       DV    G  V F+C V G     V W +      +
Sbjct: 4701 GEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWYKDGKPLKD 4760

Query: 244  MPLGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLSP 299
             P  +   LD+  +L +     +  G+YSC A N +G+ S+   L + +   PP  ++  
Sbjct: 4761 SPNIQTSFLDNIATLNIFKTDRSLSGQYSCTATNPIGSASSGAKLILTEGKNPPFFDIPL 4820

Query: 300  NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
              ++   G  A   C  TG     + W+ + NR I   G  +  Y      +    LTI 
Sbjct: 4821 APMDAVVGESADLECHVTGTQPIKVTWAKD-NREIRSGGNYQISY-----LENSAHLTIV 4874

Query: 360  DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419
              DK DS     C AVN  G      +L +   +   PP  T   S      +  +    
Sbjct: 4875 KVDKGDS-GQYTCYAVNEVGKDSCTAQLNIK--ERLIPPSFTKKLSETVEETEGNSFKLE 4931

Query: 420  TAICTPEPI-IAWYFEGEAL--IQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHGK 475
              +   +PI +AWY     +    N      N+  L+ +K    +D+G YTC A++  G 
Sbjct: 4932 GRVAGSQPITVAWYKNNVEIHPTSNCEIMFKNNALLLQVKRASMADAGLYTCKATNDAGS 4991

Query: 476  YVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSW 524
             + + ++++  P  P +     A V++  G   +   H      + + W
Sbjct: 4992 ALCTSSIVIKEPKKPPVFDQHLAPVTASEGDSVQLSCHVQGSEPIRIQW 5040



 Score =  120 bits (288), Expect = 3e-25
 Identities = 120/475 (25%), Positives = 191/475 (40%), Gaps = 28/475 (5%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
           AP I  +   + VA    A   C   G+P+   +W+K G  +      SI  +  +  L 
Sbjct: 116 APVIKRRIEPLEVALGHLAKFTCEIQGAPNVRFQWFKAGREIYESDKCSIRSSNYVSSLE 175

Query: 71  ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA-VLREEFRLEPESKQSAQGDTVVLEC 129
               +V  D G Y C+A+N YG+  S  ATL V       F   P++  +  G      C
Sbjct: 176 ILRTQV-VDCGEYTCKASNEYGSV-SCTATLTVTEAYPPTFLSRPKALTTFVGKAAKFLC 233

Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGT 188
               G+P   + W+K+G  L    D R+   D   +L + +    D G Y C A N  G 
Sbjct: 234 -TVSGTPVIEIIWQKDGAALSPSPDCRVTDADNKHSLELSNLTVQDRGIYSCKASNKFGA 292

Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
            +   A L I  KP+ I   E V +     +  +C+V  D    + W  S  G  +P G+
Sbjct: 293 -DICQAELTIIDKPHFIKELEAVQSAINKKIHLECQVDEDRKVTITW--SKDGQKLPAGK 349

Query: 249 -VKV-LDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS-INLSPNSVN 303
             K+  +D   SL +    L D G Y+C A N  G+ S+S  + V +PPS +     S  
Sbjct: 350 DYKIYFEDKIASLEIPLAKLKDSGTYTCTASNEAGSSSSSAAVAVREPPSFVKKVDPSYL 409

Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
           +  G  AR  C   G P   + W  + N+      +S       +  +   +L I D   
Sbjct: 410 MLPGESARLHCKLKGSPVIQVTW-FKNNKE-----LSESNTVRMSFVNSEAILDITDVKV 463

Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
           +DS  T  C A N  GS     ++ +     + PP          +   + A+  C    
Sbjct: 464 DDS-GTYSCEATNDVGSDSCSTEVVI-----KEPPSFIKTLEPADIVRGANALLQCEIAG 517

Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLV---LKDLDKSDSGTYTCVASSRHGK 475
           T    + W+ + + +  + +  +    T V   +   + +D G Y CV ++  GK
Sbjct: 518 TGPFEVNWFKDKKQIRSSKKYRLFTQKTFVYLEISSFNSADVGDYECVVANEVGK 572



 Score =  119 bits (287), Expect = 4e-25
 Identities = 119/477 (24%), Positives = 191/477 (40%), Gaps = 25/477 (5%)

Query: 37   GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
            G+P   I+W K  V +VS     I   G   FL   +    S  G Y C+ TN  G+   
Sbjct: 2016 GTPPFKIKWLKDDVELVSGPKCFIGLEGSTSFLNL-YSVDSSKTGQYTCQVTNDVGSDSC 2074

Query: 97   RNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSR 156
                L     +   +LE  SK    GD+  LEC    GSPE  V W +N   L      +
Sbjct: 2075 TTMLLVTEPPKFVKKLEA-SKIIKAGDSARLEC-KITGSPEIQVVWYRNEHELTASDKYQ 2132

Query: 157  MHLVDGGNLVIQDARQT-DAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT 215
            M  +D   ++  ++  T D+G + C A+N AG+   +   + +   P   + P  V    
Sbjct: 2133 MTFIDSVAVIQMNSLGTEDSGDFICEAQNPAGSTSCSTKVI-VKEPPVFSSFPPIVETLK 2191

Query: 216  GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSC 272
             + V+ +C + G P  +V+W +          + KV       S+ + NV   D GEY C
Sbjct: 2192 NTEVSLECELSGTPPFEVVWYKDKRQLRSSK-KYKVASKNFHASIHILNVESTDIGEYHC 2250

Query: 273  EAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332
            +A+N VG+ +    + + +PP      NS+ V +G  A    +  G    ++ W  E   
Sbjct: 2251 KAQNEVGSDACVCAVKLKEPPKFISKLNSLTVVAGEPAELQASIEGAQPISVQWLKEKEE 2310

Query: 333  TIIFPGMSRDKYHATAVF-DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTS 391
             I      R+  +    F + V  L     +  ++    +C   N  G       LTV  
Sbjct: 2311 VI------RESENIRISFVNNVATLQFAKVEPANA-GKYICQVKNDGGVRENMATLTVLE 2363

Query: 392  DDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI--QNHRRNVTND 449
                 P +I     + T+ +       C    TPE  + WY +G+ L   Q H+ +  N 
Sbjct: 2364 -----PAVIIEKAGSMTVTVGETCALECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNK 2418

Query: 450  -GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPG 505
              +L +  ++K D+GTYT    +  GK   +  + V   + P     R  D   + G
Sbjct: 2419 ISSLKILSVEKEDAGTYTFQVQNNVGKSSCTAVVDVSDRMVPPSFTRRLKDTGGVLG 2475



 Score =  119 bits (286), Expect = 6e-25
 Identities = 121/496 (24%), Positives = 193/496 (38%), Gaps = 27/496 (5%)

Query: 5    YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
            ++T  E PY +E+P    V       L    GG+    I+W+K    +     RS+    
Sbjct: 1422 HLTVKEPPYFVEKPQSQDVNPGTRVQLKALVGGTAPMTIKWFKDNKELHPGAARSVWKDD 1481

Query: 65   GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
                L     +  +D+G Y C+ +N  GT  S+ AT+ V    +  +          G +
Sbjct: 1482 TSTILELFSAKA-ADSGTYICQLSNDVGTTSSK-ATIFVKEPPQFIKKPSPVLVLRNGQS 1539

Query: 125  VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIAR 183
               EC    G+PE  V W  +G  +       +  VDG     I +AR  ++G Y C AR
Sbjct: 1540 TTFEC-QVTGTPEIRVSWYLDGNEITDLRKYGISFVDGLATFQISNARVENSGTYVCEAR 1598

Query: 184  NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
            N AGT   +I  LK+   P  I   E V     S V  +C V G    +V W ++     
Sbjct: 1599 NDAGTASCSIE-LKVKEPPIFIRELEPVEVVKDSDVELECEVMGTTPFEVTWLKN--NKE 1655

Query: 244  MPLGRVKVLDDGS----LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
            +  G+   + +      L +     +D GEY C   N  G+ + S  + + +PPS     
Sbjct: 1656 IRSGKKYTMSEKMSVFYLHITKCDPSDVGEYQCIIANEGGSCACSARVALKEPPSFIKKI 1715

Query: 300  NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
             +V     + A F  T  G P  ++ W ++ ++ +       D  H  +  D V  L + 
Sbjct: 1716 ENVTTVLKSSATFQSTVAGSPPISITW-LKDDQIL----EENDNVH-ISFEDSVATLQVR 1769

Query: 360  DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419
              D N       C A N +G       L V      P  II    S      K      C
Sbjct: 1770 SVD-NGHSGRYTCQAKNESGIERCYAFLLV----QEPAQIIEKAKSVDVTE-KDPVTLEC 1823

Query: 420  TAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKY 476
                TPE  + W  +G+ ++ +   +++   N  +  ++ + K DSG YT    +  G  
Sbjct: 1824 VVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSS 1883

Query: 477  VWSGAL-LVDSPINPN 491
                 L ++D  I P+
Sbjct: 1884 SCDAYLRVLDQDIPPS 1899



 Score =  118 bits (284), Expect = 1e-24
 Identities = 117/489 (23%), Positives = 196/489 (40%), Gaps = 24/489 (4%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
           VT    P  + +P  +T    + A   C   G+P   I W K G  +       +  A  
Sbjct: 206 VTEAYPPTFLSRPKALTTFVGKAAKFLCTVSGTPVIEIIWQKDGAALSPSPDCRVTDADN 265

Query: 66  LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
              L  ++  V  D G+Y C+A+N +G A    A L + + +  F  E E+ QSA    +
Sbjct: 266 KHSLELSNLTVQ-DRGIYSCKASNKFG-ADICQAELTI-IDKPHFIKELEAVQSAINKKI 322

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARN 184
            LEC       +  + W K+GQ L    D +++  D   +L I  A+  D+G Y C A N
Sbjct: 323 HLECQVDEDR-KVTITWSKDGQKLPAGKDYKIYFEDKIASLEIPLAKLKDSGTYTCTASN 381

Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW-RRSAGGGN 243
            AG+  S+ A        ++       +   G S    C++ G P+  V W + +     
Sbjct: 382 EAGSSSSSAAVAVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSE 441

Query: 244 MPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
               R+  ++ +  L + +V + D G YSCEA N VG+ S S  + + +PPS   +    
Sbjct: 442 SNTVRMSFVNSEAILDITDVKVDDSGTYSCEATNDVGSDSCSTEVVIKEPPSFIKTLEPA 501

Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
           ++  G  A   C   G     + W  +  +        + +      F  + + + N  D
Sbjct: 502 DIVRGANALLQCEIAGTGPFEVNWFKDKKQ---IRSSKKYRLFTQKTFVYLEISSFNSAD 558

Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
             D    +V + V   G         V +   + PP       + T  +    V    A+
Sbjct: 559 VGD-YECVVANEVGKCG--------CVATHLLKEPPTFVKKVDDFT-ALAGQTVTLQAAV 608

Query: 423 CTPEPIIAWYFEGEALIQNH---RRNVTND-GTLVLKDLDKSDSGTYTCVASSRHGKYVW 478
              EPI   + +G+ +I+     + + +N    L + D+  S  G YTC+A +  G    
Sbjct: 609 RGSEPISVMWMKGQEVIKEDGKIKMSFSNGVAVLTIPDVQISLGGKYTCLAENEAGSQTS 668

Query: 479 SGALLVDSP 487
            G L+V  P
Sbjct: 669 VGELIVKEP 677



 Score =  117 bits (281), Expect = 2e-24
 Identities = 126/494 (25%), Positives = 197/494 (39%), Gaps = 39/494 (7%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            E P     P  V   ++   +L C   G+P   + WYK    + S     +  A   F  
Sbjct: 2176 EPPVFSSFPPIVETLKNTEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKV--ASKNFHA 2233

Query: 70   RATHGRVHS-DAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVV 126
                  V S D G Y C+A N  G+    +A +    L+E  +F  +  S     G+   
Sbjct: 2234 SIHILNVESTDIGEYHCKAQNEVGS----DACVCAVKLKEPPKFISKLNSLTVVAGEPAE 2289

Query: 127  LECLPPRGSPEPNVYWKKNGQTLLFDGDS-RMHLVDG-GNLVIQDARQTDAGRYQCIARN 184
            L+     G+   +V W K  + ++ + ++ R+  V+    L        +AG+Y C  +N
Sbjct: 2290 LQA-SIEGAQPISVQWLKEKEEVIRESENIRISFVNNVATLQFAKVEPANAGKYICQVKN 2348

Query: 185  AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
              G RE+ +ATL +     +I     +    G +   +C+V G P   V W +    G +
Sbjct: 2349 DGGVREN-MATLTVLEPAVIIEKAGSMTVTVGETCALECKVAGTPELSVEWYKD---GKL 2404

Query: 245  PLGRVK-----VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSIN 296
                 K          SL++ +V   D G Y+ + +N+VG  S +  + V D   PPS  
Sbjct: 2405 LTSSQKHKFSFYNKISSLKILSVEKEDAGTYTFQVQNNVGKSSCTAVVDVSDRMVPPSFT 2464

Query: 297  LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
                      G      C   G    ++ W  E  + +     S  KY  T   D V  L
Sbjct: 2465 RRLKDTGGVLGTSCILECKVAGSSPISIAWFHEKTKIV-----SGAKYQ-TTFSDNVCTL 2518

Query: 357  TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416
             +N  D +D   +  C A N AGS   R  LTV      PP  +      + LP K++  
Sbjct: 2519 QLNSLDSSD-MGSYTCVAANVAGSDECRALLTV----QEPPSFVKEPEPLEVLPGKNI-T 2572

Query: 417  FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRH 473
            F      TP   + W+     L++ +R N+  + T   L L ++D S SG YTCV S+  
Sbjct: 2573 FTSVIRGTPPFKVGWFRGARELVKGNRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNA 2632

Query: 474  GKYVWSGALLVDSP 487
            G+   +  L V  P
Sbjct: 2633 GQASCTTRLFVKEP 2646



 Score =  116 bits (280), Expect = 3e-24
 Identities = 123/494 (24%), Positives = 205/494 (41%), Gaps = 29/494 (5%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
            +T  E P  +++P  + V   +  T      G+P   + W++G   +V     +I     
Sbjct: 2548 LTVQEPPSFVKEPEPLEVLPGKNITFTSVIRGTPPFKVGWFRGARELVKGNRCNIYFEDT 2607

Query: 66   LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDT 124
            +  L   +  + S +G Y C  +N+ G A   + T  + V      ++  S  S + G +
Sbjct: 2608 VAELELFNIDI-SQSGEYTCVVSNNAGQA---SCTTRLFVKEPATFVKKLSDHSVEPGKS 2663

Query: 125  VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCI 181
            ++LE     G+   +V WKK+G ++      R ++V       L I  + + DAG Y C 
Sbjct: 2664 IILEG-TYTGTLPISVTWKKDGVSI--TPSERCNIVTTEKTCILEILSSTKGDAGHYSCE 2720

Query: 182  ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW-RRSAG 240
              N AG R++  A +     PY +T  E + A  G SV+ QC+V G P   V W +    
Sbjct: 2721 IENEAG-RDACDALVSTLEPPYFVTELEPLEASVGDSVSLQCQVAGTPEITVSWFKGDTK 2779

Query: 241  GGNMPLGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSIN 296
              + P  R    ++  +L  + V + D GEY+C AENS+G  ++     + +   PPS  
Sbjct: 2780 LRSTPEYRTYFTNNVATLVFNKVSINDSGEYTCMAENSIGTAASKTIFRIQERQLPPSFA 2839

Query: 297  LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
                 +    G     TC   G     + W  +G   ++   +  D+    +  D V  L
Sbjct: 2840 RQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDG---VL---LRDDENLQMSFVDNVATL 2893

Query: 357  TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416
             I  TD + S     CSA N  G++    +L  T+ + +  P     P +  +     A 
Sbjct: 2894 KILQTDLSHS-GQYSCSASNPLGTASSTARL--TAREPKKSPFFDIKPVSIDVIAGESAD 2950

Query: 417  FPCTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRH 473
            F C         + W  + + +       +T   N   L +  + K DSG YTC A++  
Sbjct: 2951 FECHVTGAQPMRVTWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDV 3010

Query: 474  GKYVWSGALLVDSP 487
            GK + S  L V  P
Sbjct: 3011 GKDMCSAQLSVKEP 3024



 Score =  113 bits (273), Expect = 2e-23
 Identities = 124/485 (25%), Positives = 187/485 (38%), Gaps = 24/485 (4%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P    Q  D+      P TL CR  GS    + WY+ GVL+  D +  +     +  L+ 
Sbjct: 2836 PSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQMSFVDNVATLKI 2895

Query: 72   THGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
                + S +G Y C A+N  GTA S    T         F ++P S     G++   EC 
Sbjct: 2896 LQTDL-SHSGQYSCSASNPLGTASSTARLTAREPKKSPFFDIKPVSIDVIAGESADFEC- 2953

Query: 131  PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTR 189
               G+    V W K+ + +   G+  +  V    +L I    + D+G+Y C A N  G +
Sbjct: 2954 HVTGAQPMRVTWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVG-K 3012

Query: 190  ESAIATLKIHIKPYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPL 246
            +   A L +   P  I   +   VA+ G S+  +C++ G P   V+W R+      +   
Sbjct: 3013 DMCSAQLSVKEPPKFIKKLDASKVAKQGESIQLECKISGSPEIKVVWFRNDSELHESWKY 3072

Query: 247  GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
                V     L ++     D G+Y CEA N VG  S S  L V  PP     P  V    
Sbjct: 3073 NMSFVNSVALLTINEASAEDTGDYICEAHNGVGDASCSTALKVKAPPVFTQKPPPVGALK 3132

Query: 307  GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV-FDGVTVLTINDTDKND 365
            G+     C  +G P   + W V+  + +     S  K+  T+  FD  T L I + +  D
Sbjct: 3133 GSDVILQCEISGTPPFEVVW-VKDRKQV----RSSKKFKITSKNFD--TSLHIFNLEAPD 3185

Query: 366  SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
                  C A N  GS         T     PP  +       TL    + +        P
Sbjct: 3186 I-GEYHCKATNEVGSD----TCACTVKFKEPPRFVKKLSDASTLIGDPVELQAVVEGFQP 3240

Query: 426  EPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482
              ++    +GE + ++    ++   N  TL L   + S SG Y C   +  G    S  L
Sbjct: 3241 ISVVWLKDKGEVIRESENVRISFVDNIATLQLGSPEASQSGKYVCQIKNDAGMRECSAVL 3300

Query: 483  LVDSP 487
             V  P
Sbjct: 3301 TVLEP 3305



 Score =  110 bits (265), Expect = 2e-22
 Identities = 124/481 (25%), Positives = 185/481 (38%), Gaps = 30/481 (6%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            E PY ++Q   V V     A+L C+  G+P   + WYKG   +       +     +  L
Sbjct: 4620 EPPYFVKQLEPVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATCKMHFKNNVATL 4679

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRN-ATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
              T     SD+G Y C A NS G   S    T+    L   F  +    Q   G  VV E
Sbjct: 4680 VFTQVD-SSDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFE 4738

Query: 129  CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAG 187
            C    GS   +V W K+G+ L    + +   +D    L I    ++ +G+Y C A N  G
Sbjct: 4739 C-AVSGSEPISVSWYKDGKPLKDSPNIQTSFLDNIATLNIFKTDRSLSGQYSCTATNPIG 4797

Query: 188  TRESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGG 241
            +  S    +    K  P+       + A  G S   +C V G     V W    R    G
Sbjct: 4798 SASSGAKLILTEGKNPPFFDIPLAPMDAVVGESADLECHVTGTQPIKVTWAKDNREIRSG 4857

Query: 242  GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLS 298
            GN  +  ++  +   L +  V   D G+Y+C A N VG  S +  L + +   PPS    
Sbjct: 4858 GNYQISYLE--NSAHLTIVKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKK 4915

Query: 299  -PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
               +V    GN  +      G    T+ W    N   I P  + +        +   +L 
Sbjct: 4916 LSETVEETEGNSFKLEGRVAGSQPITVAW--YKNNVEIHPTSNCE----IMFKNNALLLQ 4969

Query: 358  INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
            +      D+     C A N AGS+     + +   + + PP+     +  T         
Sbjct: 4970 VKRASMADA-GLYTCKATNDAGSALCTSSIVI--KEPKKPPVFDQHLAPVTASEGDSVQL 5026

Query: 418  PCTAICTPEPI-IAWYFEGEALIQNHRRNVT-NDGT--LVLKDLDKSDSGTYTCVASSRH 473
             C  +   EPI I W   G  +  + R + +   GT  L LK+  K+DSG Y C AS+  
Sbjct: 5027 SC-HVQGSEPIRIQWLKAGREVKPSDRCSFSFASGTAMLELKETAKADSGDYVCKASNVA 5085

Query: 474  G 474
            G
Sbjct: 5086 G 5086



 Score =  107 bits (258), Expect = 1e-21
 Identities = 121/490 (24%), Positives = 192/490 (39%), Gaps = 30/490 (6%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            E P  +++  D T    Q  TL     GS   ++ W KG  ++  D    +  + G+  L
Sbjct: 583  EPPTFVKKVDDFTALAGQTVTLQAAVRGSEPISVMWMKGQEVIKEDGKIKMSFSNGVAVL 642

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL--EPESKQSAQGDTVVL 127
                 ++ S  G Y C A N  G+  S    +   +++E  ++    E  Q   GD   L
Sbjct: 643  TIPDVQI-SLGGKYTCLAENEAGSQTS----VGELIVKEPAKIIERAELIQVTAGDPATL 697

Query: 128  ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAA 186
            E     G+PE    W K+G+ L+     R+   +    L    A   D+G+Y     N  
Sbjct: 698  E-YTVSGTPELKPKWYKDGRPLVASKKYRISFKNNIAQLKFYSAELHDSGQYTFEISNEV 756

Query: 187  GTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
            G+   E+    L   I P       +V +  G +    C++ G     V W +  G    
Sbjct: 757  GSSSCETTFTVLDRDIAPLFTKPLRNVDSVVGGACRLDCKIAGSLPMRVSWFKD-GKELT 815

Query: 245  PLGRVKVL---DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
               R ++       SL +  V + D G ++C A NSVG+  +SG L V +PPS    P S
Sbjct: 816  ASDRYQIAFVEGTASLEISRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGS 875

Query: 302  VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
             +V  G+         G    T+ W  +G++ ++  G     Y      +  + L +   
Sbjct: 876  RDVLPGSAVCLKSAFQGSAPLTIKW-FKGDKELVSGGSC---YITKETSE--SSLELYAV 929

Query: 362  DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
              +DS  T  C   N AGS      L V      P   I     +Q L         C  
Sbjct: 930  KTSDS-GTYTCKVSNVAGSVECSADLFV----KEPATFIEKLEPSQLLKKGDGTQLACKV 984

Query: 422  ICTPEPIIAWYFEGEALIQNHRRNVT-NDGTLVLK--DLDKSDSGTYTCVASSRHGKYVW 478
              TP   I W+     L ++ +  ++  + T VL+  D+   DSG Y C A +  G    
Sbjct: 985  TGTPPIKITWFANDRELRESSKHKMSFAESTAVLRLTDVAIEDSGEYMCEAQNEAGSDHC 1044

Query: 479  SGALLV-DSP 487
            +G ++V +SP
Sbjct: 1045 TGIVIVKESP 1054



 Score =  103 bits (248), Expect = 2e-20
 Identities = 122/502 (24%), Positives = 193/502 (38%), Gaps = 42/502 (8%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P I+    D   +  +PA   C+  G+    + WY     +       +      + L  
Sbjct: 6   PAIVTPLQDTVTSEGRPARFQCQVSGTDLK-VSWYCKDKKIKPSRFFRMTQFEDTYQLEI 64

Query: 72  THGRVHSDAGVYWCEATNSYGTARSRNATLHV----AVLRE--------EFRLEPESKQS 119
                  D G Y   A N+ G   S  ATL +    ++L E        E +  P  K+ 
Sbjct: 65  AEA-YPEDEGTYAFVANNAVGQVSS-TATLRLEAPESILHERIGQQIEMEMKAAPVIKRR 122

Query: 120 AQGDTVVLECLPP-----RGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQT 173
            +   V L  L       +G+P     W K G+ +       +   +   +L I   +  
Sbjct: 123 IEPLEVALGHLAKFTCEIQGAPNVRFQWFKAGREIYESDKCSIRSSNYVSSLEILRTQVV 182

Query: 174 DAGRYQCIARNAAGTRESAIATLKIH--IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231
           D G Y C A N  G+  S  ATL +     P  ++ P+ +    G +  F C V G P+ 
Sbjct: 183 DCGEYTCKASNEYGS-VSCTATLTVTEAYPPTFLSRPKALTTFVGKAAKFLCTVSGTPVI 241

Query: 232 DVLWRRSAGG-GNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
           +++W++        P  RV   D+  SL L N+ + D G YSC+A N  GA      LT+
Sbjct: 242 EIIWQKDGAALSPSPDCRVTDADNKHSLELSNLTVQDRGIYSCKASNKFGADICQAELTI 301

Query: 290 YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
            D P       +V           C      + T+ WS +G +      +   K +    
Sbjct: 302 IDKPHFIKELEAVQSAINKKIHLECQVDEDRKVTITWSKDGQK------LPAGKDYKIYF 355

Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN-GPSNQT 408
            D +  L I      DS  T  C+A N AGSS     + V      PP  +    PS   
Sbjct: 356 EDKIASLEIPLAKLKDS-GTYTCTASNEAGSSSSSAAVAVR----EPPSFVKKVDPSYLM 410

Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN---VTNDGTLVLKDLDKSDSGTY 465
           LP +S A   C    +P   + W+   + L +++      V ++  L + D+   DSGTY
Sbjct: 411 LPGES-ARLHCKLKGSPVIQVTWFKNNKELSESNTVRMSFVNSEAILDITDVKVDDSGTY 469

Query: 466 TCVASSRHGKYVWSGALLVDSP 487
           +C A++  G    S  +++  P
Sbjct: 470 SCEATNDVGSDSCSTEVVIKEP 491



 Score =  103 bits (246), Expect = 4e-20
 Identities = 117/490 (23%), Positives = 184/490 (37%), Gaps = 23/490 (4%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
            VT  E P  I++    +  R   A       GS    + W K    +  D +  +     
Sbjct: 1141 VTLREPPSFIKKIEATSSLRGGTAAFQATLKGSLPITVTWLKDNDEITEDDNIRMTFENN 1200

Query: 66   LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
            +  L  +   V  D G Y C+A N  G  R  +A L V         E  S    QGD  
Sbjct: 1201 VASLYLSGIEVKHD-GKYVCQAKNDAGIQRC-SALLSVKEPATIME-EAVSIDVTQGDPA 1257

Query: 126  VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARN 184
             L+ +   G+ E +  W K+GQ L      ++ + D  +++ I    + D+G Y    +N
Sbjct: 1258 TLQ-VKFSGTKEISAKWFKDGQELTLGPKYKISVTDTVSILKIISTEKKDSGEYTFEVQN 1316

Query: 185  AAGTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
              G    +++I  L + I P        + +  GS +  +C V G     + W +     
Sbjct: 1317 DVGRSSCKASINVLDLIIPPSFTKKLRKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEI 1376

Query: 243  NMPLGRVKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
            +          D +  L +  +   D G Y+C A N  G    SG+LTV +PP     P 
Sbjct: 1377 SASDKHKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHSQCSGHLTVKEPPYFVEKPQ 1436

Query: 301  SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
            S +V  G   +      G    T+ W  +     + PG +R  +      D  T+L +  
Sbjct: 1437 SQDVNPGTRVQLKALVGGTAPMTIKWFKDNKE--LHPGAARSVWKD----DTSTILELFS 1490

Query: 361  TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
                DS  T +C   N  G++  +  + V      PP  I        L       F C 
Sbjct: 1491 AKAADS-GTYICQLSNDVGTTSSKATIFV----KEPPQFIKKPSPVLVLRNGQSTTFECQ 1545

Query: 421  AICTPEPIIAWYFEGEALIQNHRRNVT-NDG--TLVLKDLDKSDSGTYTCVASSRHGKYV 477
               TPE  ++WY +G  +    +  ++  DG  T  + +    +SGTY C A +  G   
Sbjct: 1546 VTGTPEIRVSWYLDGNEITDLRKYGISFVDGLATFQISNARVENSGTYVCEARNDAGTAS 1605

Query: 478  WSGALLVDSP 487
             S  L V  P
Sbjct: 1606 CSIELKVKEP 1615



 Score =  103 bits (246), Expect = 4e-20
 Identities = 118/510 (23%), Positives = 188/510 (36%), Gaps = 30/510 (5%)

Query: 31   LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
            L C+  GS   +I W+     +VS        +  +  L+  +    SD G Y C A N 
Sbjct: 2480 LECKVAGSSPISIAWFHEKTKIVSGAKYQTTFSDNVCTLQL-NSLDSSDMGSYTCVAANV 2538

Query: 91   YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
             G+   R A L V      F  EPE  +   G  +    +  RG+P   V W +  + L+
Sbjct: 2539 AGSDECR-ALLTVQE-PPSFVKEPEPLEVLPGKNITFTSVI-RGTPPFKVGWFRGARELV 2595

Query: 151  FDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
                  ++  D    L + +   + +G Y C+  N AG + S    L +      +    
Sbjct: 2596 KGNRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAG-QASCTTRLFVKEPATFVKKLS 2654

Query: 210  DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA---D 266
            D   + G S+  +    G     V W++  G    P  R  ++      +  ++ +   D
Sbjct: 2655 DHSVEPGKSIILEGTYTGTLPISVTWKKD-GVSITPSERCNIVTTEKTCILEILSSTKGD 2713

Query: 267  EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326
             G YSCE EN  G  +    ++  +PP        +    G+     C   G PE T+ W
Sbjct: 2714 AGHYSCEIENEAGRDACDALVSTLEPPYFVTELEPLEASVGDSVSLQCQVAGTPEITVSW 2773

Query: 327  SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
              +G+  +     S  +Y  T   + V  L  N    NDS     C A N  G++    K
Sbjct: 2774 -FKGDTKL----RSTPEYR-TYFTNNVATLVFNKVSINDS-GEYTCMAENSIGTA--ASK 2824

Query: 387  LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT---PEPI-IAWYFEGEALIQNH 442
                  + + PP      + Q   I+     P T  C      PI + WY +G  L  + 
Sbjct: 2825 TIFRIQERQLPPSF----ARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDE 2880

Query: 443  RRN---VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAAD 499
                  V N  TL +   D S SG Y+C AS+  G    +  L    P        +   
Sbjct: 2881 NLQMSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSTARLTAREPKKSPFFDIKPVS 2940

Query: 500  VSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
            +  + G       H      + ++WS++NK
Sbjct: 2941 IDVIAGESADFECHVTGAQPMRVTWSKDNK 2970



 Score =  101 bits (243), Expect = 9e-20
 Identities = 116/488 (23%), Positives = 185/488 (37%), Gaps = 27/488 (5%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDT-HRSILPAGGLF 67
            E P  I++  +VT      AT      GSP  +I W K   +L  +D  H S   +    
Sbjct: 1707 EPPSFIKKIENVTTVLKSSATFQSTVAGSPPISITWLKDDQILEENDNVHISFEDSVATL 1766

Query: 68   FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
             +R+     HS  G Y C+A N  G  R   A L V    +    + +S    + D V L
Sbjct: 1767 QVRSVDNG-HS--GRYTCQAKNESGIERCY-AFLLVQEPAQIIE-KAKSVDVTEKDPVTL 1821

Query: 128  ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAA 186
            EC+   G+PE  V W K+G+ ++      M   +   +  IQ   + D+G+Y     N  
Sbjct: 1822 ECVVA-GTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDF 1880

Query: 187  GTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
            G+   ++ +  L   I P        +    GSS+  +C+V G       W +     + 
Sbjct: 1881 GSSSCDAYLRVLDQDIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEIST 1940

Query: 245  PLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
                  V  +   SL + N+ L D   Y+C+  N  G  + SG LTV +PPS  + P   
Sbjct: 1941 SAKYRLVCHENTVSLEVSNLELEDTANYTCKVSNVAGDNACSGILTVKEPPSFLVKPERQ 2000

Query: 303  NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
                 +   F     G P   + W  +    +  P        +T+  +  +V    D+ 
Sbjct: 2001 QAIPDSTVEFKAVLKGTPPFKIKWLKDDVELVSGPKCFIGLEGSTSFLNLYSV----DSS 2056

Query: 363  KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
            K        C   N  GS      L VT     PP  +    +++ +     A   C   
Sbjct: 2057 KT---GQYTCQVTNDVGSDSCTTMLLVT----EPPKFVKKLEASKIIKAGDSARLECKIT 2109

Query: 423  CTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479
             +PE  + WY     L  + +  +T   +   + +  L   DSG + C A +  G    S
Sbjct: 2110 GSPEIQVVWYRNEHELTASDKYQMTFIDSVAVIQMNSLGTEDSGDFICEAQNPAGSTSCS 2169

Query: 480  GALLVDSP 487
              ++V  P
Sbjct: 2170 TKVIVKEP 2177



 Score =  101 bits (243), Expect = 9e-20
 Identities = 118/527 (22%), Positives = 191/527 (36%), Gaps = 26/527 (4%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P  + +  D +        L CR  GS   ++ W+  G  ++S        A  +  L  
Sbjct: 3402 PSFVRRLKDTSATLGASVVLECRVSGSAPISVGWFLDGNEIISSPKCQSSFADNVCTLTL 3461

Query: 72   THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
            +     SD G Y C A N  G   S +A L V      F   P+S +   G ++    + 
Sbjct: 3462 S-SLEPSDTGAYTCVAANVAGQDES-SAVLTVQE-PPSFEQTPDSVEVLPGMSLTFTSVI 3518

Query: 132  PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRE 190
             RG+P   V W K  + L+      + L D    L + +     +G Y C+  N AG   
Sbjct: 3519 -RGTPPFKVKWFKGSRELVSGEACTISLEDFVTELELLEVEPGQSGDYSCLVTNDAG--- 3574

Query: 191  SAIATLKIHIKP--YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLG 247
            SA  T  + +K     +    D   +TGS +  +    G P   V W ++       P  
Sbjct: 3575 SASCTTHLFVKEPATFVKRLADTSVETGSPIVLEATYSGTPPISVSWMKNEYPLSQSPNC 3634

Query: 248  RVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
             +   +  S L +    + D  +Y+C  EN  G       ++V +PP        V    
Sbjct: 3635 GITTTEKSSILEILESTIEDYAQYACLIENEAGQDICEALVSVLEPPYFIEPLEHVEAAI 3694

Query: 307  GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
            G      C   G PE  + W  E  +    P       +     + V  L IN  D +D 
Sbjct: 3695 GEPITLQCKVDGTPEIRISWYKEHTKLRSAPA------YKMQFKNNVASLVINKVDHSDV 3748

Query: 367  RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
                 C A N  G+  V     +   + + PP       +    +     F C  I   E
Sbjct: 3749 -GEYTCKAENSVGA--VASSAVLVIKERKLPPSFARKLKDVHETLGFPVAFECR-INGSE 3804

Query: 427  PI-IAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482
            P+ ++WY +GE L  +    ++   +  TL +   D+S  G Y C AS+  G    S  L
Sbjct: 3805 PLQVSWYKDGELLKDDANLQMSFVHHVATLQILQTDQSHVGQYNCSASNPLGTASSSAKL 3864

Query: 483  LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
            ++     P     +   V    G       H      + ++W+++N+
Sbjct: 3865 ILSEHEVPPFFDLKPVSVDLALGESGSFKCHVTGTAPIKITWAKDNR 3911



 Score =  101 bits (242), Expect = 1e-19
 Identities = 118/477 (24%), Positives = 189/477 (39%), Gaps = 29/477 (6%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFF 68
            E P  I +   +TV   +PA L     G+   +++W K    V+ ++    I     +  
Sbjct: 2269 EPPKFISKLNSLTVVAGEPAELQASIEGAQPISVQWLKEKEEVIRESENIRISFVNNVAT 2328

Query: 69   LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDTVVL 127
            L+       ++AG Y C+  N  G  R   ATL   VL     +E     +   G+T  L
Sbjct: 2329 LQFAKVEP-ANAGKYICQVKND-GGVRENMATL--TVLEPAVIIEKAGSMTVTVGETCAL 2384

Query: 128  ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAA 186
            EC    G+PE +V W K+G+ L      +    +   +L I    + DAG Y    +N  
Sbjct: 2385 EC-KVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLKILSVEKEDAGTYTFQVQNNV 2443

Query: 187  GTRESAIATLKIH---IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
            G + S  A + +    + P      +D     G+S   +C+V G     + W        
Sbjct: 2444 G-KSSCTAVVDVSDRMVPPSFTRRLKDTGGVLGTSCILECKVAGSSPISIAWFHEKTKIV 2502

Query: 244  MPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
                      D   +L+L+++  +D G Y+C A N  G+      LTV +PPS    P  
Sbjct: 2503 SGAKYQTTFSDNVCTLQLNSLDSSDMGSYTCVAANVAGSDECRALLTVQEPPSFVKEPEP 2562

Query: 302  VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
            + V  G    FT    G P   + W   G R ++  G   + Y      D V  L + + 
Sbjct: 2563 LEVLPGKNITFTSVIRGTPPFKVGW-FRGARELV-KGNRCNIYFE----DTVAELELFNI 2616

Query: 362  DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
            D + S     C   N AG +    +L V      P   +     +   P KS+ +   T 
Sbjct: 2617 DISQS-GEYTCVVSNNAGQASCTTRLFV----KEPATFVKKLSDHSVEPGKSI-ILEGTY 2670

Query: 422  ICTPEPIIAWYFEGEALIQNHRRN-VTNDGTLVLKDLD--KSDSGTYTCVASSRHGK 475
              T    + W  +G ++  + R N VT + T +L+ L   K D+G Y+C   +  G+
Sbjct: 2671 TGTLPISVTWKKDGVSITPSERCNIVTTEKTCILEILSSTKGDAGHYSCEIENEAGR 2727



 Score =  101 bits (242), Expect = 1e-19
 Identities = 122/500 (24%), Positives = 199/500 (39%), Gaps = 37/500 (7%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P    Q  DV      P    C   GS   ++ WYK G  +    +        +  L  
Sbjct: 4718 PSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWYKDGKPLKDSPNIQTSFLDNIATLNI 4777

Query: 72   THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDTVVLECL 130
                  S +G Y C ATN  G+A S    +        F   P +   A  G++  LEC 
Sbjct: 4778 FKTD-RSLSGQYSCTATNPIGSASSGAKLILTEGKNPPFFDIPLAPMDAVVGESADLEC- 4835

Query: 131  PPRGSPEPNVYWKKNGQTLLFDGDSRM-HLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
               G+    V W K+ + +   G+ ++ +L +  +L I    + D+G+Y C A N  G +
Sbjct: 4836 HVTGTQPIKVTWAKDNREIRSGGNYQISYLENSAHLTIVKVDKGDSGQYTCYAVNEVG-K 4894

Query: 190  ESAIATLKIH---IKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
            +S  A L I    I P       + V +T G+S   + RV G     V W ++    + P
Sbjct: 4895 DSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNVEIH-P 4953

Query: 246  LGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP---PSINLSP 299
                +++   +   L++    +AD G Y+C+A N  G+   +  + + +P   P  +   
Sbjct: 4954 TSNCEIMFKNNALLLQVKRASMADAGLYTCKATNDAGSALCTSSIVIKEPKKPPVFDQHL 5013

Query: 300  NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
              V    G+  + +C   G     + W   G    + P    D+  + +   G  +L + 
Sbjct: 5014 APVTASEGDSVQLSCHVQGSEPIRIQWLKAGRE--VKPS---DRC-SFSFASGTAMLELK 5067

Query: 360  DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP----------IITNGPSNQTL 409
            +T K DS +  VC A N AGS   + K+T+       P              + P +  +
Sbjct: 5068 ETAKADSGD-YVCKASNVAGSDTSKCKVTIKEKPAAAPAAKKAAVDGKLFFVSEPQSIRV 5126

Query: 410  PIKSMAVFPCTAICTPEPIIAWYF-EGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTY 465
              K+ A F       P P + W   +   L Q  R  +   G    L ++D  K+DSG Y
Sbjct: 5127 VEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRILIHQKGDEAKLEIRDTTKTDSGLY 5186

Query: 466  TCVASSRHGKYVWSGALLVD 485
             CVA ++HG+   +  L VD
Sbjct: 5187 RCVAFNKHGEIESNVNLQVD 5206



 Score =  100 bits (239), Expect = 3e-19
 Identities = 118/492 (23%), Positives = 192/492 (39%), Gaps = 35/492 (7%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            E P  +++  D +     P  L     G    ++ W K    V+ ++    +        
Sbjct: 3210 EPPRFVKKLSDASTLIGDPVELQAVVEGFQPISVVWLKDKGEVIRESENVRISFVDNIAT 3269

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLE 128
                    S +G Y C+  N  G    R  +  + VL     +E PE      G+   LE
Sbjct: 3270 LQLGSPEASQSGKYVCQIKNDAGM---RECSAVLTVLEPATIVEKPEPMTVTTGNPFTLE 3326

Query: 129  CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV---IQDARQTDAGRYQCIARNA 185
            C+   G+PE +  W K+G+ L     SR H+    NL    I  A   D G Y     N 
Sbjct: 3327 CVVA-GTPELSAKWFKDGREL--SSGSRHHITFVRNLASLKIPSAEMNDKGLYTFEVENR 3383

Query: 186  AGTRESAIATLKIHIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
             G    +  T+ +H+      P  +   +D  A  G+SV  +CRV G     V W     
Sbjct: 3384 VG---KSSCTVSVHVSDRVVPPSFVRRLKDTSATLGASVVLECRVSGSAPISVGWFLDGN 3440

Query: 241  GG-NMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
               + P  +    D+  +L L ++  +D G Y+C A N  G   +S  LTV +PPS   +
Sbjct: 3441 EIISSPKCQSSFADNVCTLTLSSLEPSDTGAYTCVAANVAGQDESSAVLTVQEPPSFEQT 3500

Query: 299  PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
            P+SV V  G    FT    G P   + W  +G+R ++       +    ++ D VT L +
Sbjct: 3501 PDSVEVLPGMSLTFTSVIRGTPPFKVKW-FKGSRELV-----SGEACTISLEDFVTELEL 3554

Query: 359  NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
             + +   S     C   N AGS+     L V     + P       ++ ++   S  V  
Sbjct: 3555 LEVEPGQS-GDYSCLVTNDAGSASCTTHLFV-----KEPATFVKRLADTSVETGSPIVLE 3608

Query: 419  CTAICTPEPIIAWYFEGEALIQNHRRNV-TNDGTLVLKDLDKS--DSGTYTCVASSRHGK 475
             T   TP   ++W      L Q+    + T + + +L+ L+ +  D   Y C+  +  G+
Sbjct: 3609 ATYSGTPPISVSWMKNEYPLSQSPNCGITTTEKSSILEILESTIEDYAQYACLIENEAGQ 3668

Query: 476  YVWSGALLVDSP 487
             +    + V  P
Sbjct: 3669 DICEALVSVLEP 3680



 Score = 89.4 bits (212), Expect = 5e-16
 Identities = 110/465 (23%), Positives = 176/465 (37%), Gaps = 26/465 (5%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            E P  + +P    V       L     GS    I+W+KG   +VS     I        L
Sbjct: 865  EPPSFVTKPGSRDVLPGSAVCLKSAFQGSAPLTIKWFKGDKELVSGGSCYITKETSESSL 924

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEF-RLEPESKQSAQGDTVVLE 128
                 +  SD+G Y C+ +N  G+    +A L V        +LEP S+   +GD   L 
Sbjct: 925  ELYAVKT-SDSGTYTCKVSNVAGSVEC-SADLFVKEPATFIEKLEP-SQLLKKGDGTQLA 981

Query: 129  CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAG 187
            C    G+P   + W  N + L      +M   +   ++ + D    D+G Y C A+N AG
Sbjct: 982  C-KVTGTPPIKITWFANDRELRESSKHKMSFAESTAVLRLTDVAIEDSGEYMCEAQNEAG 1040

Query: 188  TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
            + +     + +   PY     + +       V     V G P  ++ W +          
Sbjct: 1041 S-DHCTGIVIVKESPYFTKEFKSIEVLKEYDVMLLAEVAGTPPFEITWFKDNTTLRSGRK 1099

Query: 248  RVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
                L D   SL++   + AD GEY C   N VG+ + S  +T+ +PPS      + +  
Sbjct: 1100 YKTFLQDQLVSLQVLKFVAADAGEYQCRVTNEVGSSTCSARVTLREPPSFIKKIEATSSL 1159

Query: 306  SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD-KN 364
             G  A F  T  G    T+ W  + +       ++ D        + V  L ++  + K+
Sbjct: 1160 RGGTAAFQATLKGSLPITVTWLKDNDE------ITEDDNIRMTFENNVASLYLSGIEVKH 1213

Query: 365  DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
            D +   VC A N AG       L+V     + P  I     +  +     A        T
Sbjct: 1214 DGK--YVCQAKNDAGIQRCSALLSV-----KEPATIMEEAVSIDVTQGDPATLQVKFSGT 1266

Query: 425  PEPIIAWYFEGEALIQNHRRNVT-NDGTLVLK--DLDKSDSGTYT 466
             E    W+ +G+ L    +  ++  D   +LK    +K DSG YT
Sbjct: 1267 KEISAKWFKDGQELTLGPKYKISVTDTVSILKIISTEKKDSGEYT 1311



 Score = 39.1 bits (87), Expect = 0.72
 Identities = 31/121 (25%), Positives = 56/121 (46%), Gaps = 12/121 (9%)

Query: 122  GDTVVLECLPPRGSPEPNVY-WKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRY 178
            G + + ECL    SP   +  W K+G  +  +      + DG +  L I D + +DAG Y
Sbjct: 8126 GSSAIFECLV---SPSTAITTWMKDGSNIR-ESPKHRFIADGKDRKLHIIDVQLSDAGEY 8181

Query: 179  QCIAR--NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
             C+ R  N   T  + +   ++ ++ ++ T  E+V    G  +   C +  +   DV+WR
Sbjct: 8182 TCVLRLGNKEKTSTAKLIVEELPVR-FVKTLEEEVTVVKGQPLYLSCELNKE--RDVVWR 8238

Query: 237  R 237
            +
Sbjct: 8239 K 8239


>UniRef50_Q4RY92 Cluster: Chromosome 3 SCAF14978, whole genome shotgun
            sequence; n=4; Vertebrata|Rep: Chromosome 3 SCAF14978,
            whole genome shotgun sequence - Tetraodon nigroviridis
            (Green puffer)
          Length = 2222

 Score =  136 bits (328), Expect = 5e-30
 Identities = 144/545 (26%), Positives = 236/545 (43%), Gaps = 69/545 (12%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWYK--GGVLVVSDT---HRSILPAGGLFFLRATHG 74
            ++T+A      ++C   G+    IRW    G  L  S     +  + P G +       G
Sbjct: 1523 NITLAEGSDVYIHCNISGALQAKIRWITPDGTQLTTSQFSTGNNRVFPNGTIHI----PG 1578

Query: 75   RVHSDAGVYWCEATNSYGTAR-----SRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
                + G Y C ATNS  ++R     S   +L  +  R  F   P+      G++++L+C
Sbjct: 1579 LTKKNTGRYECLATNSLVSSRRVVMLSLKRSLSSSKARVVFS-SPQRTDVIYGESLLLDC 1637

Query: 130  LPPRGSPEPNVYWKKNGQTLL---FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
            +   G P P + W+   + L+   +  DSR+ ++  G + I+   + D+G Y C+ARN  
Sbjct: 1638 VTT-GEPTPRIIWRTPSKKLVDAQYSFDSRIMVLANGTIAIRSVTEKDSGDYLCVARNKI 1696

Query: 187  GTRESAIATLKIHIKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
            G  +  +  + +  +P  I   +   +Q    G  +   C   G P P++ W    G   
Sbjct: 1697 GD-DYILLRVNVMTRPAKIKQKQQHSSQEVIYGGDLKVDCVASGLPNPEISWALPDGTMV 1755

Query: 244  MPL-------GRVK---VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY--- 290
             P+       GR +   V D+G+L  ++V + +EG+Y+C AEN +G       + V    
Sbjct: 1756 DPVKTRDSSGGRSRRYVVFDNGTLYFNDVGMPEEGDYTCYAENKLGKDEMKVTVKVKVAT 1815

Query: 291  DPPSI-NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
            +PP I +   N V    G+    TC A G P P + W    +R I     + DK+    +
Sbjct: 1816 NPPKIQDKKQNLVKGFYGDTVVLTCNAKGEPLPVITWISPTSRVIT---STVDKHQI--L 1870

Query: 350  FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT--NGPSN- 406
             DG   L I    + D  N   C A N AG  F   +L V        P+I   +G SN 
Sbjct: 1871 NDGT--LIIQKVQRFDGGN-YSCVARNNAGQDFKVTRLEVLVTS----PVINGLSGTSNI 1923

Query: 407  --QTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI----QNHRRNVTNDGTLVLKDLDKS 460
               T     +    C A  TP P + W   G  ++     ++R  V  +GTL ++ L ++
Sbjct: 1924 ITVTAVQDQIKFLDCVAKGTPTPRVMWLLPGNVILPAPYNSNRMTVHQNGTLEIRSLKRT 1983

Query: 461  DSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSV 520
            D+G  TC+A +  G+      L V+  +N       AA+ S + GP T+ ++  V  T +
Sbjct: 1984 DAGKLTCIARNEGGEV----RLSVNLSVN------EAAEKSHISGPKTQSLSLTVGST-M 2032

Query: 521  TLSWS 525
            TL+ S
Sbjct: 2033 TLNCS 2037



 Score =  119 bits (287), Expect = 4e-25
 Identities = 129/512 (25%), Positives = 212/512 (41%), Gaps = 46/512 (8%)

Query: 12   PYIIEQPL--DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT--------HRSIL 61
            P +I QP   DVTV       L+C   G P+P + W     + V+          H SIL
Sbjct: 1413 PPLILQPRQRDVTVNLGGKIHLDCAVEGHPTPRVTWVLPNRVHVAPVPHGTPSWQHVSIL 1472

Query: 62   PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA-VLREEFRLEPESKQSA 120
              G L    A      +D G+Y C  +++ G+       +HV+ +L E  + + ++   A
Sbjct: 1473 SNGTLRISEAAF----ADRGIYKCIGSSTAGSDAVL-VRVHVSGILSEVQQTQYQNITLA 1527

Query: 121  QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGD---SRMHLVDGGNLVIQDARQTDAGR 177
            +G  V + C    G+ +  + W     T L           +   G + I    + + GR
Sbjct: 1528 EGSDVYIHC-NISGALQAKIRWITPDGTQLTTSQFSTGNNRVFPNGTIHIPGLTKKNTGR 1586

Query: 178  YQCIARNA-AGTRESAIATLKIHIKP----YLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
            Y+C+A N+   +R   + +LK  +       + + P+      G S+   C   G+P P 
Sbjct: 1587 YECLATNSLVSSRRVVMLSLKRSLSSSKARVVFSSPQRTDVIYGESLLLDCVTTGEPTPR 1646

Query: 233  VLWR----RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
            ++WR    +          R+ VL +G++ + +V   D G+Y C A N +G       + 
Sbjct: 1647 IIWRTPSKKLVDAQYSFDSRIMVLANGTIAIRSVTEKDSGDYLCVARNKIGDDYILLRVN 1706

Query: 289  VYDPPSI---NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRD--- 342
            V   P+        +S  V  G   +  C A+G P P + W++    T++ P  +RD   
Sbjct: 1707 VMTRPAKIKQKQQHSSQEVIYGGDLKVDCVASGLPNPEISWALPDG-TMVDPVKTRDSSG 1765

Query: 343  -KYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401
             +     VFD  T L  ND    +  +   C A N  G   +  K+TV       PP I 
Sbjct: 1766 GRSRRYVVFDNGT-LYFNDVGMPEEGD-YTCYAENKLGKDEM--KVTVKVKVATNPPKIQ 1821

Query: 402  NGPSNQTLPIKS-MAVFPCTAICTPEPIIAWYFEGEALIQN--HRRNVTNDGTLVLKDLD 458
            +   N          V  C A   P P+I W      +I +   +  + NDGTL+++ + 
Sbjct: 1822 DKKQNLVKGFYGDTVVLTCNAKGEPLPVITWISPTSRVITSTVDKHQILNDGTLIIQKVQ 1881

Query: 459  KSDSGTYTCVASSRHGK--YVWSGALLVDSPI 488
            + D G Y+CVA +  G+   V    +LV SP+
Sbjct: 1882 RFDGGNYSCVARNNAGQDFKVTRLEVLVTSPV 1913



 Score =  108 bits (259), Expect = 1e-21
 Identities = 123/496 (24%), Positives = 199/496 (40%), Gaps = 49/496 (9%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV----SDTHRSIL 61
            ++S +A  +   P    V   +   L+C   G P+P I W      +V    S   R ++
Sbjct: 1610 LSSSKARVVFSSPQRTDVIYGESLLLDCVTTGEPTPRIIWRTPSKKLVDAQYSFDSRIMV 1669

Query: 62   PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
             A G   +R+       D+G Y C A N  G        L V V+    +++ + + S+Q
Sbjct: 1670 LANGTIAIRSV---TEKDSGDYLCVARNKIG---DDYILLRVNVMTRPAKIKQKQQHSSQ 1723

Query: 122  ----GDTVVLECLPPRGSPEPNVYWKKNGQTLL--------FDGDSRMHLV-DGGNLVIQ 168
                G  + ++C+   G P P + W     T++          G SR ++V D G L   
Sbjct: 1724 EVIYGGDLKVDCV-ASGLPNPEISWALPDGTMVDPVKTRDSSGGRSRRYVVFDNGTLYFN 1782

Query: 169  DARQTDAGRYQCIARNAAGTRESAIAT-LKIHIKPYLITGPED--VVAQTGSSVTFQCRV 225
            D    + G Y C A N  G  E  +   +K+   P  I   +   V    G +V   C  
Sbjct: 1783 DVGMPEEGDYTCYAENKLGKDEMKVTVKVKVATNPPKIQDKKQNLVKGFYGDTVVLTCNA 1842

Query: 226  GGDPLPDVLW-RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSA 283
             G+PLP + W   ++      + + ++L+DG+L +  V   D G YSC A N+ G     
Sbjct: 1843 KGEPLPVITWISPTSRVITSTVDKHQILNDGTLIIQKVQRFDGGNYSCVARNNAGQDFKV 1902

Query: 284  SGYLTVYDPPSIN-LSPNS----VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPG 338
            +    +   P IN LS  S    V      +    C A G P P + W + GN  +I P 
Sbjct: 1903 TRLEVLVTSPVINGLSGTSNIITVTAVQDQIKFLDCVAKGTPTPRVMWLLPGN--VILPA 1960

Query: 339  MSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398
               +    T   +G   L I    + D+   + C A N  G   +   L+V    ++   
Sbjct: 1961 -PYNSNRMTVHQNG--TLEIRSLKRTDA-GKLTCIARNEGGEVRLSVNLSVNEAAEKSH- 2015

Query: 399  IITNGPSNQ--TLPIKSMAVFPCTAICTPEPIIAWYF-EGEAL---IQNHRRNVTNDGTL 452
               +GP  Q  +L + S     C++     P + W    G  L    Q  +     DG+L
Sbjct: 2016 --ISGPKTQSLSLTVGSTMTLNCSSEGAHLPRVIWILPNGTPLNSGAQLSKFFNRPDGSL 2073

Query: 453  VLKDLDKSDSGTYTCV 468
            ++ +   S++GTY C+
Sbjct: 2074 IITNPSVSEAGTYRCL 2089



 Score =  102 bits (244), Expect = 7e-20
 Identities = 116/499 (23%), Positives = 189/499 (37%), Gaps = 57/499 (11%)

Query: 31   LNCRAGGSPSPAIRWYK--GGVLVVSDT--HRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
            L C A G P P + W K   G ++  +T  HR  +   G   +R T      D G Y C+
Sbjct: 1337 LPCEADGEPRPFLSWTKVVSGTVIAQNTRVHRFEVHPNGTLTIRNTQ---PMDGGEYLCK 1393

Query: 87   ATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSA--QGDTVVLECLPPRGSPEPNVYW- 142
              N +GT        +V +L +    L+P  +      G  + L+C    G P P V W 
Sbjct: 1394 VQNQHGT---DTMVANVVILSQPPLILQPRQRDVTVNLGGKIHLDC-AVEGHPTPRVTWV 1449

Query: 143  ---KKNGQTLLFDGDSRMH--LVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
               + +   +     S  H  ++  G L I +A   D G Y+CI  + AG   S    ++
Sbjct: 1450 LPNRVHVAPVPHGTPSWQHVSILSNGTLRISEAAFADRGIYKCIGSSTAG---SDAVLVR 1506

Query: 198  IHIKPYLI----TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG----GGNMPLGRV 249
            +H+   L     T  +++    GS V   C + G     + W    G          G  
Sbjct: 1507 VHVSGILSEVQQTQYQNITLAEGSDVYIHCNISGALQAKIRWITPDGTQLTTSQFSTGNN 1566

Query: 250  KVLDDGSLRLDNVILADEGEYSCEAENS------VGAVSASGYLTVYDPPSINLSPNSVN 303
            +V  +G++ +  +   + G Y C A NS      V  +S    L+      +  SP   +
Sbjct: 1567 RVFPNGTIHIPGLTKKNTGRYECLATNSLVSSRRVVMLSLKRSLSSSKARVVFSSPQRTD 1626

Query: 304  VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
            V  G      C  TG P P + W    ++ ++    S D          + + ++ + D 
Sbjct: 1627 VIYGESLLLDCVTTGEPTPRIIWRTP-SKKLVDAQYSFDSRIMVLANGTIAIRSVTEKDS 1685

Query: 364  NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP-SNQTLPIKSMAVFPCTAI 422
             D     +C A N  G  ++  ++ V +   RP  I      S+Q +         C A 
Sbjct: 1686 GD----YLCVARNKIGDDYILLRVNVMT---RPAKIKQKQQHSSQEVIYGGDLKVDCVAS 1738

Query: 423  CTPEPIIAWYFEGEALI-----------QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
              P P I+W      ++           ++ R  V ++GTL   D+   + G YTC A +
Sbjct: 1739 GLPNPEISWALPDGTMVDPVKTRDSSGGRSRRYVVFDNGTLYFNDVGMPEEGDYTCYAEN 1798

Query: 472  RHGKYVWSGALLVDSPINP 490
            + GK      + V    NP
Sbjct: 1799 KLGKDEMKVTVKVKVATNP 1817



 Score =  102 bits (244), Expect = 7e-20
 Identities = 112/466 (24%), Positives = 198/466 (42%), Gaps = 45/466 (9%)

Query: 31   LNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRATHGRVH-SDAGV-----Y 83
            ++C A G P+P I W    G +V     R         ++   +G ++ +D G+     Y
Sbjct: 1733 VDCVASGLPNPEISWALPDGTMVDPVKTRDSSGGRSRRYVVFDNGTLYFNDVGMPEEGDY 1792

Query: 84   WCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG---DTVVLECLPPRGSPEPNV 140
             C A N  G    +  T+ V V     +++ + +   +G   DTVVL C   +G P P +
Sbjct: 1793 TCYAENKLGKDEMK-VTVKVKVATNPPKIQDKKQNLVKGFYGDTVVLTC-NAKGEPLPVI 1850

Query: 141  YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
             W      ++     +  +++ G L+IQ  ++ D G Y C+ARN AG ++  +  L++ +
Sbjct: 1851 TWISPTSRVITSTVDKHQILNDGTLIIQKVQRFDGGNYSCVARNNAG-QDFKVTRLEVLV 1909

Query: 201  -KPYL--ITGPEDVVAQTG--SSVTF-QCRVGGDPLPDVLWRRSAGGGNMPL----GRVK 250
              P +  ++G  +++  T     + F  C   G P P V+W    G   +P      R+ 
Sbjct: 1910 TSPVINGLSGTSNIITVTAVQDQIKFLDCVAKGTPTPRVMW-LLPGNVILPAPYNSNRMT 1968

Query: 251  VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLS---PNSVNVES 306
            V  +G+L + ++   D G+ +C A N  G V  S  L+V +     ++S     S+++  
Sbjct: 1969 VHQNGTLEIRSLKRTDAGKLTCIARNEGGEVRLSVNLSVNEAAEKSHISGPKTQSLSLTV 2028

Query: 307  GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
            G+     C++ G   P + W +  N T +  G    K+      DG  ++T         
Sbjct: 2029 GSTMTLNCSSEGAHLPRVIW-ILPNGTPLNSGAQLSKFFNRP--DGSLIIT---NPSVSE 2082

Query: 367  RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
              T  C   ++ G   V  K+T+T    R P I     S  +  I    +  C  +   E
Sbjct: 2083 AGTYRCLWRDFQG--LVERKITLT--PGRKPEITNRYNSPISTMIGERLLLHC--LTNSE 2136

Query: 427  PI-IAWYFEGEALIQN----HRRNVTNDGTLVLKDLDKSDSGTYTC 467
            P+ + W      ++       R NV ++GTL +  +   D G+Y C
Sbjct: 2137 PLRLTWTLPSGVVLNRPQKAGRYNVLSNGTLAIHQISTYDRGSYVC 2182



 Score = 89.8 bits (213), Expect = 4e-16
 Identities = 89/376 (23%), Positives = 145/376 (38%), Gaps = 26/376 (6%)

Query: 119  SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD---GGNLVIQDARQTDA 175
            +A+ +T V       G P P + W K     +   ++R+H  +    G L I++ +  D 
Sbjct: 1328 TAKAETDVQLPCEADGEPRPFLSWTKVVSGTVIAQNTRVHRFEVHPNGTLTIRNTQPMDG 1387

Query: 176  GRYQCIARNAAGTRESAIATLKIHIKPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDV 233
            G Y C  +N  GT ++ +A + I  +P LI  P   DV    G  +   C V G P P V
Sbjct: 1388 GEYLCKVQNQHGT-DTMVANVVILSQPPLILQPRQRDVTVNLGGKIHLDCAVEGHPTPRV 1446

Query: 234  LW--RRSAGGGNMPLG-----RVKVLDDGSLRLDNVILADEGEYSCEAENSVG--AVSAS 284
             W          +P G      V +L +G+LR+     AD G Y C   ++ G  AV   
Sbjct: 1447 TWVLPNRVHVAPVPHGTPSWQHVSILSNGTLRISEAAFADRGIYKCIGSSTAGSDAVLVR 1506

Query: 285  GYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
             +++            ++ +  G+     C  +G  +  + W       +     S    
Sbjct: 1507 VHVSGILSEVQQTQYQNITLAEGSDVYIHCNISGALQAKIRWITPDGTQLTTSQFSTGN- 1565

Query: 345  HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV-TSDDDRPPPIITNG 403
                VF   T+     T KN  R    C A N   SS     L++  S       ++ + 
Sbjct: 1566 --NRVFPNGTIHIPGLTKKNTGR--YECLATNSLVSSRRVVMLSLKRSLSSSKARVVFSS 1621

Query: 404  PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ-----NHRRNVTNDGTLVLKDLD 458
            P    +      +  C     P P I W    + L+      + R  V  +GT+ ++ + 
Sbjct: 1622 PQRTDVIYGESLLLDCVTTGEPTPRIIWRTPSKKLVDAQYSFDSRIMVLANGTIAIRSVT 1681

Query: 459  KSDSGTYTCVASSRHG 474
            + DSG Y CVA ++ G
Sbjct: 1682 EKDSGDYLCVARNKIG 1697



 Score = 76.6 bits (180), Expect = 4e-12
 Identities = 72/269 (26%), Positives = 116/269 (43%), Gaps = 17/269 (6%)

Query: 19   LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS---DTHRSILPAGGLFFLRATHGR 75
            + VT  + Q   L+C A G+P+P + W   G +++    +++R  +   G   +R+    
Sbjct: 1924 ITVTAVQDQIKFLDCVAKGTPTPRVMWLLPGNVILPAPYNSNRMTVHQNGTLEIRSLK-- 1981

Query: 76   VHSDAGVYWCEATNSYGTAR-SRNATLHVAVLREEFR-LEPESKQSAQGDTVVLECLPPR 133
              +DAG   C A N  G  R S N +++ A  +      + +S     G T+ L C    
Sbjct: 1982 -RTDAGKLTCIARNEGGEVRLSVNLSVNEAAEKSHISGPKTQSLSLTVGSTMTLNC-SSE 2039

Query: 134  GSPEPNVYWKKNGQTLLFDGD--SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
            G+  P V W     T L  G   S+      G+L+I +   ++AG Y+C+ R+  G  E 
Sbjct: 2040 GAHLPRVIWILPNGTPLNSGAQLSKFFNRPDGSLIITNPSVSEAGTYRCLWRDFQGLVER 2099

Query: 192  AIATLKIHIKPYLITGPEDVVA-QTGSSVTFQCRVGGDPLPDVLWRRSAGGG-NMP--LG 247
             I TL    KP +       ++   G  +   C    +PL  + W   +G   N P   G
Sbjct: 2100 KI-TLTPGRKPEITNRYNSPISTMIGERLLLHCLTNSEPL-RLTWTLPSGVVLNRPQKAG 2157

Query: 248  RVKVLDDGSLRLDNVILADEGEYSCEAEN 276
            R  VL +G+L +  +   D G Y C   N
Sbjct: 2158 RYNVLSNGTLAIHQISTYDRGSYVCRVAN 2186



 Score = 63.7 bits (148), Expect = 3e-08
 Identities = 69/285 (24%), Positives = 111/285 (38%), Gaps = 21/285 (7%)

Query: 201  KPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG----NMPLGRVKVLDDG 255
            KP +  G  +   A+  + V   C   G+P P + W +   G     N  + R +V  +G
Sbjct: 1316 KPRITKGSFQTFTAKAETDVQLPCEADGEPRPFLSWTKVVSGTVIAQNTRVHRFEVHPNG 1375

Query: 256  SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVNVESGNVARFT 313
            +L + N    D GEY C+ +N  G  +    + +   P + L P    V V  G      
Sbjct: 1376 TLTIRNTQPMDGGEYLCKVQNQHGTDTMVANVVILSQPPLILQPRQRDVTVNLGGKIHLD 1435

Query: 314  CTATGRPEPTMFWSVEGNRTII--FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371
            C   G P P + W V  NR  +   P  +    H + + +G   L I++    D R    
Sbjct: 1436 CAVEGHPTPRVTW-VLPNRVHVAPVPHGTPSWQHVSILSNG--TLRISEAAFAD-RGIYK 1491

Query: 372  CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431
            C   + AGS  V  ++ V+        +      N TL   S     C      +  I W
Sbjct: 1492 CIGSSTAGSDAVLVRVHVSGILSE---VQQTQYQNITLAEGSDVYIHCNISGALQAKIRW 1548

Query: 432  YF-EGEALIQNH----RRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
               +G  L  +        V  +GT+ +  L K ++G Y C+A++
Sbjct: 1549 ITPDGTQLTTSQFSTGNNRVFPNGTIHIPGLTKKNTGRYECLATN 1593



 Score = 55.2 bits (127), Expect = 1e-05
 Identities = 49/167 (29%), Positives = 71/167 (42%), Gaps = 17/167 (10%)

Query: 31  LNCRAGGSPSPAIRWY-----KGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85
           LNC    S  P I+W      K      S  +R  +  GG   ++A     H+D G+Y+C
Sbjct: 378 LNCNVHSSGHPVIQWTLPDGSKVEAPYSSPDNRVSVSNGGQLVIKAVS---HTDTGIYYC 434

Query: 86  EATNSYGTARSRNATLHVAVLREEFRLEPESK---QSAQGDTVVLECLPPRGSPEPNVYW 142
            A      A       H+ V         E     Q   G  + L C+   GSP+  VYW
Sbjct: 435 TAKVQGDFA---VLPFHLTVQESSSPSPGEDVSPFQGFAGKPISLPCI-TFGSPDAEVYW 490

Query: 143 -KKNGQTLLFDGD-SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
              + + + F G+ SR H++  G L I   + +D+G Y+CIA N  G
Sbjct: 491 ILPSSKIVSFHGNSSRAHVLLNGTLHIPQTQLSDSGHYKCIAINQHG 537



 Score = 47.2 bits (107), Expect = 0.003
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 18/137 (13%)

Query: 154 DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP---ED 210
           D+R+ + +GG LVI+    TD G Y C A+      +   A L  H+     + P   ED
Sbjct: 408 DNRVSVSNGGQLVIKAVSHTDTGIYYCTAK-----VQGDFAVLPFHLTVQESSSPSPGED 462

Query: 211 V---VAQTGSSVTFQCRVGGDPLPDVLW-----RRSAGGGNMPLGRVKVLDDGSLRLDNV 262
           V       G  ++  C   G P  +V W     +  +  GN    R  VL +G+L +   
Sbjct: 463 VSPFQGFAGKPISLPCITFGSPDAEVYWILPSSKIVSFHGNS--SRAHVLLNGTLHIPQT 520

Query: 263 ILADEGEYSCEAENSVG 279
            L+D G Y C A N  G
Sbjct: 521 QLSDSGHYKCIAINQHG 537



 Score = 45.6 bits (103), Expect = 0.008
 Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 8/87 (9%)

Query: 395  RPPPIITNGPSNQTLPIKSMA--VFPCTAICTPEPIIAW--YFEGEALIQN---HRRNVT 447
            R  P IT G S QT   K+      PC A   P P ++W     G  + QN   HR  V 
Sbjct: 1314 RGKPRITKG-SFQTFTAKAETDVQLPCEADGEPRPFLSWTKVVSGTVIAQNTRVHRFEVH 1372

Query: 448  NDGTLVLKDLDKSDSGTYTCVASSRHG 474
             +GTL +++    D G Y C   ++HG
Sbjct: 1373 PNGTLTIRNTQPMDGGEYLCKVQNQHG 1399



 Score = 45.2 bits (102), Expect = 0.011
 Identities = 40/185 (21%), Positives = 74/185 (40%), Gaps = 11/185 (5%)

Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
           S N++   ++   G+ +   C       P + W++     +  P  S D   + +    +
Sbjct: 360 SKNITRKVLSALLGSQSELNCNVHSSGHPVIQWTLPDGSKVEAPYSSPDNRVSVSNGGQL 419

Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413
            +  ++ TD         C+A      + +   LTV  +   P P     P  Q    K 
Sbjct: 420 VIKAVSHTDTG----IYYCTAKVQGDFAVLPFHLTV-QESSSPSPGEDVSPF-QGFAGKP 473

Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNH----RRNVTNDGTLVLKDLDKSDSGTYTCVA 469
           +++ PC    +P+  + W      ++  H    R +V  +GTL +     SDSG Y C+A
Sbjct: 474 ISL-PCITFGSPDAEVYWILPSSKIVSFHGNSSRAHVLLNGTLHIPQTQLSDSGHYKCIA 532

Query: 470 SSRHG 474
            ++HG
Sbjct: 533 INQHG 537



 Score = 41.9 bits (94), Expect = 0.10
 Identities = 47/194 (24%), Positives = 72/194 (37%), Gaps = 13/194 (6%)

Query: 213 AQTGSSVTFQCRVGGDPLPDVLWRRSAGGG-----NMPLGRVKVLDDGSLRLDNVILADE 267
           A  GS     C V     P + W    G       + P  RV V + G L +  V   D 
Sbjct: 370 ALLGSQSELNCNVHSSGHPVIQWTLPDGSKVEAPYSSPDNRVSVSNGGQLVIKAVSHTDT 429

Query: 268 GEYSCEAENSVGAVSASGYLTVYD--PPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325
           G Y C A+          +LTV +   PS     +     +G      C   G P+  ++
Sbjct: 430 GIYYCTAKVQGDFAVLPFHLTVQESSSPSPGEDVSPFQGFAGKPISLPCITFGSPDAEVY 489

Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385
           W +  ++ + F G S     A  + +G   L I  T  +DS +   C A+N  G   +  
Sbjct: 490 WILPSSKIVSFHGNSS---RAHVLLNG--TLHIPQTQLSDSGH-YKCIAINQHGVDTLVT 543

Query: 386 KLTVTSDDDRPPPI 399
           K T+   +    P+
Sbjct: 544 KTTLIKQNGPIMPL 557


>UniRef50_UPI0000DB6C79 Cluster: PREDICTED: similar to PTK7 protein
           tyrosine kinase 7 isoform a precursor; n=1; Apis
           mellifera|Rep: PREDICTED: similar to PTK7 protein
           tyrosine kinase 7 isoform a precursor - Apis mellifera
          Length = 1112

 Score =  134 bits (323), Expect = 2e-29
 Identities = 138/488 (28%), Positives = 205/488 (42%), Gaps = 45/488 (9%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWY-KGGVLVVSDTHRSILPAG 64
           V+S E   +   P D+   R +PA L+C    + S  ++W+ K    + +D  R++   G
Sbjct: 211 VSSNETASVKVVPRDLIAKRGEPAVLHCVFEDADS--VQWFFKDMGPLETDDERTVFENG 268

Query: 65  GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEP--ESKQSA 120
            L    A H     D G Y C       T  S    L +A L        EP   S+ + 
Sbjct: 269 TLVIRSAEH----RDQGFYSCHGDRGESTI-SYTVDLQIAYLMNLSAASFEPLLSSQVAV 323

Query: 121 QGDTVVLE--CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ-TDAGR 177
            G+   L+  CL P G P P VYW+     ++   DS    V    L++  AR   D G 
Sbjct: 324 VGEEQELQVSCLEPSGLPPPRVYWRDPKGHII--SDSGPVRVQDNTLIVAKARMGEDDGN 381

Query: 178 YQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGG--DPLPDVLW 235
           Y C+A N AG  + + A + I   P LI+ PE++    G SVT  C   G   P+  V W
Sbjct: 382 YTCVAENMAGETDIS-AQVVISTPPTLISSPENLSVMEGDSVTMTCSYSGMDAPVTHVRW 440

Query: 236 RRSAGGGNMPLG--RVKVLD---DGSLRLDNVILADEGEYSCE--AENSVGAVSASGYLT 288
            +         G  R +V D   + +L L +  L+D+G Y+CE   +      S    LT
Sbjct: 441 LKDGEPLKESGGPTRHRVTDHHGNVTLHLKSADLSDKGGYACEITTKGFPPIFSERAGLT 500

Query: 289 VYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
           V +    +  P    +E G+ A+  C + G   PT+ W  EG+    FP   +D  + T 
Sbjct: 501 VEEKLKFSPQPVDKRLELGSTAKVPCKSQGATNPTVKWIKEGSGEE-FPKHVQD-INGTL 558

Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408
            F+GV           + +    C A N  GS  +   +++   D    P  T  P N T
Sbjct: 559 HFNGVL---------EEDKGRYTCIASNAQGS--INHTISI---DVVIAPKFTIQPQNPT 604

Query: 409 LPIKSMAVF-PCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYT 466
             I+   V   C A   P+P I W  +     + N R  V  +G+L +K++  SD G Y 
Sbjct: 605 EAIEGYPVMLHCAAEGDPKPTIQWDRDSRMNNLNNSRFEVLGNGSLYIKEVYMSDEGKYG 664

Query: 467 CVASSRHG 474
           C A +  G
Sbjct: 665 CTAGNSGG 672



 Score =  112 bits (270), Expect = 5e-23
 Identities = 92/309 (29%), Positives = 133/309 (43%), Gaps = 17/309 (5%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPA--IRWYKGGVLVVSD---THRSILPAGGL 66
           P +I  P +++V      T+ C   G  +P   +RW K G  +      T   +    G 
Sbjct: 405 PTLISSPENLSVMEGDSVTMTCSYSGMDAPVTHVRWLKDGEPLKESGGPTRHRVTDHHGN 464

Query: 67  FFLRATHGRVHSDAGVYWCE-ATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
             L      + SD G Y CE  T  +    S  A L V   + +F  +P  K+   G T 
Sbjct: 465 VTLHLKSADL-SDKGGYACEITTKGFPPIFSERAGLTVEE-KLKFSPQPVDKRLELGSTA 522

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARN 184
            + C   +G+  P V W K G    F      H+ D  G L      + D GRY CIA N
Sbjct: 523 KVPC-KSQGATNPTVKWIKEGSGEEFP----KHVQDINGTLHFNGVLEEDKGRYTCIASN 577

Query: 185 AAGTRESAIATLKIHIKPYLITGPED-VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
           A G+    I ++ + I P     P++   A  G  V   C   GDP P + W R +   N
Sbjct: 578 AQGSINHTI-SIDVVIAPKFTIQPQNPTEAIEGYPVMLHCAAEGDPKPTIQWDRDSRMNN 636

Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
           +   R +VL +GSL +  V ++DEG+Y C A NS G       L V D  S++   N ++
Sbjct: 637 LNNSRFEVLGNGSLYIKEVYMSDEGKYGCTAGNSGGLKREEVQLNVKD-TSVDERVNHLS 695

Query: 304 VESGNVARF 312
             +G+  RF
Sbjct: 696 STAGDTYRF 704



 Score =  105 bits (252), Expect = 7e-21
 Identities = 122/544 (22%), Positives = 205/544 (37%), Gaps = 33/544 (6%)

Query: 10  EAPYIIEQP-LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
           EA   ++QP L   +       L C   GS      W++     V+ + R  +    L  
Sbjct: 121 EASVQLQQPKLPSAIRVGGEIELRCHVDGSGDIKYEWFRNRE-PVARSDRIEIKKKKLHV 179

Query: 69  LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVV 126
            RA    V  D+G+Y C A N  G++    +   +    E    ++ P    + +G+  V
Sbjct: 180 HRA----VAEDSGMYNCLAKNDAGSSPKMESFPLIVSSNETASVKVVPRDLIAKRGEPAV 235

Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
           L C+        +V W       L   D R  + + G LVI+ A   D G Y C      
Sbjct: 236 LHCV---FEDADSVQWFFKDMGPLETDDERT-VFENGTLVIRSAEHRDQGFYSCHGDRGE 291

Query: 187 GTRESAIATLKIHIKPYLITGPEDV----VAQTGSSVTFQ--C-RVGGDPLPDVLWRRSA 239
            T    +     ++        E +    VA  G     Q  C    G P P V WR   
Sbjct: 292 STISYTVDLQIAYLMNLSAASFEPLLSSQVAVVGEEQELQVSCLEPSGLPPPRVYWRDPK 351

Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
           G      G V+V D+  +     +  D+G Y+C AEN  G    S  + +  PP++  SP
Sbjct: 352 GHIISDSGPVRVQDNTLIVAKARMGEDDGNYTCVAENMAGETDISAQVVISTPPTLISSP 411

Query: 300 NSVNVESGNVARFTCTATGRPEPT--MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
            +++V  G+    TC+ +G   P   + W  +G       G +R   H      G   L 
Sbjct: 412 ENLSVMEGDSVTMTCSYSGMDAPVTHVRWLKDGEPLKESGGPTR---HRVTDHHGNVTLH 468

Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
           +   D +D +    C             +  +T ++       +  P ++ L + S A  
Sbjct: 469 LKSADLSD-KGGYACEITTKGFPPIFSERAGLTVEEKLK---FSPQPVDKRLELGSTAKV 524

Query: 418 PCTAICTPEPIIAWYFEGEA-LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476
           PC +     P + W  EG       H +++  +GTL    + + D G YTC+AS+  G  
Sbjct: 525 PCKSQGATNPTVKWIKEGSGEEFPKHVQDI--NGTLHFNGVLEEDKGRYTCIASNAQGSI 582

Query: 477 VWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSIL 536
             +  + +D  I P           ++ G P         D   T+ W +++++ + +  
Sbjct: 583 --NHTISIDVVIAPKFTIQPQNPTEAIEGYPVMLHCAAEGDPKPTIQWDRDSRMNNLNNS 640

Query: 537 GYQV 540
            ++V
Sbjct: 641 RFEV 644


>UniRef50_Q4S2G4 Cluster: Chromosome undetermined SCAF14761, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF14761,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 912

 Score =  134 bits (323), Expect = 2e-29
 Identities = 117/431 (27%), Positives = 177/431 (41%), Gaps = 33/431 (7%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK--GGVLVVSDTHRSILPAGGLF 67
           E P   E P D+     +  TL C A GSP P + W++  G  ++     R +    G  
Sbjct: 505 EDPLFSETPADLMAKIGENVTLRCSARGSPQPTVSWHRHDGRQILTGSRSRMVQLEDGHL 564

Query: 68  FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
            ++   G   SD G+Y CEA N +GT ++        ++  E    P    + +G ++ L
Sbjct: 565 LIQ---GVWLSDEGLYVCEAKNPFGTIKTGARLSVTGLVPPEIHAGPYHYIANEGVSITL 621

Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
            C    G P+P+V W   G +L       + +       I      DAG Y C + N  G
Sbjct: 622 FC-KSSGVPKPDVVW---GGSLSLGTMLPVSVHQMATFHIPHPTTDDAGIYVCTSTNPVG 677

Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
                I  L ++ KP +      + A  G SVT  C V G+P P+V W  +     +P+G
Sbjct: 678 YASREI-QLSVNTKPRIQPAATLLKALIGQSVTLPCVVQGEPSPEVTWFHN----GLPVG 732

Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE-- 305
              + +   LR+    L D+G Y C A NS G  ++   L + D PS    P    +E  
Sbjct: 733 ---IKNTTPLRIQKAKLNDQGTYKCVATNSAGQETSEIKLDILDAPSF-AEPGDALLEKV 788

Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
           +       C A G P P + W   G    I P  S  +   +   DG   LTI+    + 
Sbjct: 789 ANTKVIIPCPAEGSPRPKIRWYRNGLE--IHPEQSSPELFVSE--DG--ALTISSASASH 842

Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
           S    +C A N AGS   + +L +  D    PP+   G   + + +       C     P
Sbjct: 843 S-GDFMCVATNEAGSVERKTRLKIEGD----PPVF--GIQEEKVRMNGSLTLACMTKGFP 895

Query: 426 EPIIAWYFEGE 436
           EP I W+ +G+
Sbjct: 896 EPKIQWFKDGQ 906



 Score =  128 bits (309), Expect = 9e-28
 Identities = 106/373 (28%), Positives = 150/373 (40%), Gaps = 34/373 (9%)

Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN-GQTLLFDGDSRMHLVDGGNLVIQ 168
           F   P    +  G+ V L C   RGSP+P V W ++ G+ +L    SRM  ++ G+L+IQ
Sbjct: 509 FSETPADLMAKIGENVTLRC-SARGSPQPTVSWHRHDGRQILTGSRSRMVQLEDGHLLIQ 567

Query: 169 DARQTDAGRYQCIARNAAGT-RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGG 227
               +D G Y C A+N  GT +  A  ++   + P +  GP   +A  G S+T  C+  G
Sbjct: 568 GVWLSDEGLYVCEAKNPFGTIKTGARLSVTGLVPPEIHAGPYHYIANEGVSITLFCKSSG 627

Query: 228 DPLPDVLWRRSAGGGNMPLGR---VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSAS 284
            P PDV+W     GG++ LG    V V    +  + +    D G Y C + N VG  S  
Sbjct: 628 VPKPDVVW-----GGSLSLGTMLPVSVHQMATFHIPHPTTDDAGIYVCTSTNPVGYASRE 682

Query: 285 GYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
             L+V   P I  +   +    G      C   G P P + W   G    I         
Sbjct: 683 IQLSVNTKPRIQPAATLLKALIGQSVTLPCVVQGEPSPEVTWFHNGLPVGI--------- 733

Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404
                    T L I     ND + T  C A N AG      KL +       P     G 
Sbjct: 734 ------KNTTPLRIQKAKLND-QGTYKCVATNSAGQETSEIKLDILD----APSFAEPGD 782

Query: 405 SNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN---VTNDGTLVLKDLDKSD 461
           +       +  + PC A  +P P I WY  G  +          V+ DG L +     S 
Sbjct: 783 ALLEKVANTKVIIPCPAEGSPRPKIRWYRNGLEIHPEQSSPELFVSEDGALTISSASASH 842

Query: 462 SGTYTCVASSRHG 474
           SG + CVA++  G
Sbjct: 843 SGDFMCVATNEAG 855



 Score = 92.3 bits (219), Expect = 7e-17
 Identities = 74/278 (26%), Positives = 112/278 (40%), Gaps = 26/278 (9%)

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDGSLRL 259
           P     P D++A+ G +VT +C   G P P V W R  G   +   R ++  L+DG L +
Sbjct: 507 PLFSETPADLMAKIGENVTLRCSARGSPQPTVSWHRHDGRQILTGSRSRMVQLEDGHLLI 566

Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYD--PPSINLSPNSVNVESGNVARFTCTAT 317
             V L+DEG Y CEA+N  G +     L+V    PP I+  P       G      C ++
Sbjct: 567 QGVWLSDEGLYVCEAKNPFGTIKTGARLSVTGLVPPEIHAGPYHYIANEGVSITLFCKSS 626

Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
           G P+P + W    +   + P       H  A F      T       D     VC++ N 
Sbjct: 627 GVPKPDVVWGGSLSLGTMLP----VSVHQMATFHIPHPTT-------DDAGIYVCTSTNP 675

Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437
            G +    +L+V +      P I    +     I      PC     P P + W+  G  
Sbjct: 676 VGYASREIQLSVNT-----KPRIQPAATLLKALIGQSVTLPCVVQGEPSPEVTWFHNGLP 730

Query: 438 LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
           +       + N   L ++    +D GTY CVA++  G+
Sbjct: 731 V------GIKNTTPLRIQKAKLNDQGTYKCVATNSAGQ 762



 Score = 49.6 bits (113), Expect = 5e-04
 Identities = 51/226 (22%), Positives = 87/226 (38%), Gaps = 40/226 (17%)

Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTI--------------IFPG---------MSRDK 343
           G+  RF C+A+G P P +FWS  GN  +              +FPG           +D 
Sbjct: 381 GDEIRFVCSASGSPTPQLFWS-HGNTFLTNRLRYITDQYCLCMFPGEFEVGSTLFAGQDD 439

Query: 344 YHATAVFDGVTVLT------INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR-- 395
           YH T    GV  +       +  +    +  T+       +       + T+ SD  +  
Sbjct: 440 YHGTLHIRGVQKVDAGQYTCVASSPAGTATGTVSLKVGGESAFQCFNTEPTLPSDCTQRR 499

Query: 396 -----PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY-FEGEALIQNHRRNVTN- 448
                  P+ +  P++    I       C+A  +P+P ++W+  +G  ++   R  +   
Sbjct: 500 FSPLTEDPLFSETPADLMAKIGENVTLRCSARGSPQPTVSWHRHDGRQILTGSRSRMVQL 559

Query: 449 -DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIH 493
            DG L+++ +  SD G Y C A +  G       L V   + P IH
Sbjct: 560 EDGHLLIQGVWLSDEGLYVCEAKNPFGTIKTGARLSVTGLVPPEIH 605


>UniRef50_O94856 Cluster: Neurofascin precursor; n=64;
           Euteleostomi|Rep: Neurofascin precursor - Homo sapiens
           (Human)
          Length = 1347

 Score =  133 bits (322), Expect = 2e-29
 Identities = 125/469 (26%), Positives = 202/469 (43%), Gaps = 44/469 (9%)

Query: 31  LNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGLFFLR-ATHGRVHSDAGVYWCEA 87
           + C A G+P+P+  W +      +  D   S+    G   +   + GR     G Y C A
Sbjct: 61  IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 120

Query: 88  TNSYGTARSRNATLHVAV--LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
            N +GTA S    L V+   L  +  L+P   Q  +G  + L+C PP G P P ++W  +
Sbjct: 121 RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQ--EGAPLTLQCNPPPGLPSPVIFWMSS 178

Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIAR-NAAGT-RESAIATLKI---- 198
               +   D R+     G+L   +    D    Y C AR +   T ++    TLK+    
Sbjct: 179 SMEPITQ-DKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTR 237

Query: 199 ---HIKPYLI----TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
                 P  +    T    +V + G  +  +C   G P PD+ W +   GG++P  + K 
Sbjct: 238 GVAERTPSFMYPQGTASSQMVLR-GMDLLLECIASGVPTPDIAWYKK--GGDLPSDKAKF 294

Query: 252 LD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310
            + + +LR+ NV   D GEY C A N +G++  +  + V   P     P ++ +  G   
Sbjct: 295 ENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDG 354

Query: 311 RFTCTATGRPEPTMFWSVEGN-RTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
           R  C A G P+PT+ W V G       P  +R+    T +F         DT +  SR  
Sbjct: 355 RLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIF--------RDT-QISSRAV 405

Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEP 427
             C+  N  G       ++V    D PP +++  P NQ + +   +     C    +P P
Sbjct: 406 YQCNTSNEHGYLLANAFVSVL---DVPPRMLS--PRNQLIRVILYNRTRLDCPFFGSPIP 460

Query: 428 IIAWYFEGE-ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
            + W+  G+ + +     +V  +G+L +K + K D G YTCVA++  GK
Sbjct: 461 TLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGK 509



 Score =  114 bits (275), Expect = 1e-23
 Identities = 86/284 (30%), Positives = 134/284 (47%), Gaps = 15/284 (5%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS---DTHRSILPAGGLF 67
           APY +++P ++ +A  +   L CRA G+P P ++W   G  + S   + +R +  AG   
Sbjct: 336 APYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREV--AGDTI 393

Query: 68  FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTV 125
             R T     S   VY C  +N +G   + NA + V  +     L P ++  +    +  
Sbjct: 394 IFRDTQ---ISSRAVYQCNTSNEHGYLLA-NAFVSVLDVPPRM-LSPRNQLIRVILYNRT 448

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
            L+C P  GSP P + W KNGQ    DG    H+ + G+L I+  R+ D G Y C+A N 
Sbjct: 449 RLDC-PFFGSPIPTLRWFKNGQGSNLDG-GNYHVYENGSLEIKMIRKEDQGIYTCVATNI 506

Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
            G  E+ +  L++     +   PED VA+ G++V  +CRV  DP   +          + 
Sbjct: 507 LGKAENQV-RLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLY 565

Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
           +G     +D SL +  V   D+G Y+C A   +    A  YLTV
Sbjct: 566 IGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 609



 Score =  113 bits (272), Expect = 3e-23
 Identities = 159/620 (25%), Positives = 249/620 (40%), Gaps = 65/620 (10%)

Query: 10  EAPYIIEQPLD-VTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHR-SILPAGGL 66
           ++P   ++ LD V V    P TL C    G PSP I W    +  ++   R S    G L
Sbjct: 138 KSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDL 197

Query: 67  FFLRATHGRVHSDAGVYWCEATNSYG-TARSRNA-TLHVAVLREEFR-----LEPESKQS 119
           +F       + +D   Y C A   +  T + +N  TL V   R         + P+   S
Sbjct: 198 YFSNVMLQDMQTD---YSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTAS 254

Query: 120 AQ----GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175
           +Q    G  ++LEC+   G P P++ W K G  L  D     +      L I +  + D+
Sbjct: 255 SQMVLRGMDLLLECIAS-GVPTPDIAWYKKGGDLPSDKAKFENFNKA--LRITNVSEEDS 311

Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
           G Y C+A N  G+    I+ +++   PY +  P++++   G      CR  G+P P V W
Sbjct: 312 GEYFCLASNKMGSIRHTIS-VRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQW 370

Query: 236 RRSAGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
             +        P    +V  D  +  D  I +    Y C   N  G + A+ +++V D P
Sbjct: 371 MVNGEPLQSAPPNPNREVAGDTIIFRDTQI-SSRAVYQCNTSNEHGYLLANAFVSVLDVP 429

Query: 294 SINLSPNS--VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
              LSP +  + V   N  R  C   G P PT+ W   G  + +  G     YH   V++
Sbjct: 430 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGG----NYH---VYE 482

Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
             + L I    K D +    C A N  G +  + +L V     + P  I   P +Q    
Sbjct: 483 NGS-LEIKMIRKED-QGIYTCVATNILGKAENQVRLEV-----KDPTRIYRMPEDQVARR 535

Query: 412 KSMAVFPCTAICTP--EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
            +     C     P  +  ++W  + E L   +R    +D +L +  + + D G+YTCVA
Sbjct: 536 GTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDD-SLTIFGVAERDQGSYTCVA 594

Query: 470 SSRHGKYVWSGAL--LVDSPINPNIHFFRAADVSSLP-GPPTKPITHNVTD---TSVTLS 523
           S+   + +    L  L D     N        +++LP G P +P    +TD    SV L+
Sbjct: 595 STELDQDLAKAYLTVLADQATPTN-------RLAALPKGRPDRPRDLELTDLAERSVRLT 647

Query: 524 WSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITY 583
           W   +   +S I  Y V+    +   G         W   ++     +  V  L P + Y
Sbjct: 648 WIPGD-ANNSPITDYVVQFEEDQFQPG--------VWHDHSKYPGSVNSAVLRLSPYVNY 698

Query: 584 MFIVRTENSHGLSGPSPVSD 603
            F V   N  G S PS  S+
Sbjct: 699 QFRVIAINEVGSSHPSLPSE 718



 Score = 88.2 bits (209), Expect = 1e-15
 Identities = 103/395 (26%), Positives = 157/395 (39%), Gaps = 44/395 (11%)

Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR-----QTDAGR 177
           D +++EC   +G+P P+ +W +N +      D R+ +      ++ D R     +   G 
Sbjct: 57  DNILIEC-EAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGE 115

Query: 178 YQCIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVLW 235
           YQC ARN  GT  S    L++   P +     + VV Q G+ +T QC    G P P + W
Sbjct: 116 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFW 175

Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILAD-EGEYSCEAE-NSVGAVSASGYLTV---- 289
             S+        RV    +G L   NV+L D + +YSC A  +    +      T+    
Sbjct: 176 MSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLT 235

Query: 290 -----YDPPSINL---SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341
                   PS      + +S  V  G      C A+G P P + W  +G        +  
Sbjct: 236 TRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGG------DLPS 289

Query: 342 DKYHATAVFDGVT-VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII 400
           DK    A F+     L I +  + DS     C A N  GS  +R  ++V     +  P  
Sbjct: 290 DK----AKFENFNKALRITNVSEEDS-GEYFCLASNKMGS--IRHTISVRV---KAAPYW 339

Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ---NHRRNVTNDGTLVLKDL 457
            + P N  L         C A   P+P + W   GE L     N  R V  D T++ +D 
Sbjct: 340 LDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD-TIIFRDT 398

Query: 458 DKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
             S    Y C  S+ HG Y+ + A +    + P +
Sbjct: 399 QISSRAVYQCNTSNEHG-YLLANAFVSVLDVPPRM 432



 Score = 62.9 bits (146), Expect = 5e-08
 Identities = 70/279 (25%), Positives = 111/279 (39%), Gaps = 17/279 (6%)

Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLD-DGSLRLD----NV 262
           +D +     ++  +C   G+P P   W R++   N+    RV +    G+L +D      
Sbjct: 49  KDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGR 108

Query: 263 ILADEGEYSCEAENSVG-AVSASGYLTVYDPP---SINLSPNSVNVESGNVARFTCTAT- 317
               EGEY C A N  G A+S    L V   P     NL P  V V+ G      C    
Sbjct: 109 PEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDP--VVVQEGAPLTLQCNPPP 166

Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
           G P P +FW       I         ++    F  V +L    TD + +        +  
Sbjct: 167 GLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNV-MLQDMQTDYSCNARFHFTHTIQQ 225

Query: 378 AGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIKSM-AVFPCTAICTPEPIIAWYFEG 435
             + F    LT     +R P  +   G ++  + ++ M  +  C A   P P IAWY +G
Sbjct: 226 K-NPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKG 284

Query: 436 EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
             L  +  +    +  L + ++ + DSG Y C+AS++ G
Sbjct: 285 GDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMG 323


>UniRef50_Q4SR22 Cluster: Chromosome 11 SCAF14528, whole genome
           shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 11
           SCAF14528, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 1154

 Score =  133 bits (321), Expect = 3e-29
 Identities = 89/298 (29%), Positives = 139/298 (46%), Gaps = 10/298 (3%)

Query: 20  DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
           +  + + +   L C A G P+P + W K G  +   T  +I   G L F+         D
Sbjct: 226 EARLVKGEDLNLECIAAGFPTPQVEWVKMGQRL--PTKATIESHGKLLFVPTVE---QED 280

Query: 80  AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
            G Y C+A N+ G A     T+ V     E+  EPES+ S  G  V+++C    G+P+P 
Sbjct: 281 GGKYMCKAKNTLGEA-VHYFTVTVEG-PPEWVSEPESQLSMIGSDVLIKC-SVSGTPQPT 337

Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
           V W+ NG  L  D  +    V G  +V+ + + +D+  YQC A N  GT  S    + ++
Sbjct: 338 VTWRVNGNRLQ-DSPAPNRRVLGDTIVLHNTKPSDSAVYQCEASNRHGTLLSNANIMIMN 396

Query: 200 IKPYLIT-GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLR 258
             P ++T   ED  A  G  V   C+V   P P + W +     ++   R  V D+G+L 
Sbjct: 397 FPPMILTENDEDYSAVEGKRVMMHCKVFSSPSPTITWSKDDTSDSVDGPRFSVHDNGTLE 456

Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316
           +      D G Y+C A+N+ G+ + +  L+V DP  I   P    +  G  A+F+C A
Sbjct: 457 IYRAEKEDAGPYTCFAKNTEGSSAINAMLSVKDPTRIVEPPEDSRILKGTTAQFSCLA 514



 Score =  130 bits (313), Expect = 3e-28
 Identities = 123/481 (25%), Positives = 194/481 (40%), Gaps = 40/481 (8%)

Query: 31  LNCRAGGSPSPAIRWYKGGVLVVSDTH-RSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
           + C A G+P P  RW K G         R I       F+   +G +    G+Y C A+N
Sbjct: 26  MKCEAKGNPEPQFRWTKNGQQFDPFLDPRLIKEEDSGTFVIPNNGNLTEYQGIYRCFASN 85

Query: 90  SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
             GTA SR     V  + +  +   +     +G   VL+C PP G P   +YW       
Sbjct: 86  VLGTAISREIEFIVPNVPKFPKETIDPVVVEEGQPFVLKCNPPDGIPPLQIYWMTISLQH 145

Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIA----------RNAAG----TRESA-- 192
           + + D R+     G+L    A   D+ R Y C A          + A      T++ A  
Sbjct: 146 I-EQDERVSTSLNGDLYFSHAVDKDSRRDYCCFAAFPRIRTIVQKTAMSVIVKTKKDASP 204

Query: 193 -IATLKIHIKPYLITGP---EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
            +A   +  +P ++T P    +     G  +  +C   G P P V W +   G  +P  +
Sbjct: 205 EVANAILQRRPSIMTPPGGKSEARLVKGEDLNLECIAAGFPTPQVEWVKM--GQRLPT-K 261

Query: 249 VKVLDDGSLR-LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESG 307
             +   G L  +  V   D G+Y C+A+N++G       +TV  PP     P S     G
Sbjct: 262 ATIESHGKLLFVPTVEQEDGGKYMCKAKNTLGEAVHYFTVTVEGPPEWVSEPESQLSMIG 321

Query: 308 NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
           +     C+ +G P+PT+ W V GNR    P  +R     T V        +++T  +DS 
Sbjct: 322 SDVLIKCSVSGTPQPTVTWRVNGNRLQDSPAPNRRVLGDTIV--------LHNTKPSDSA 373

Query: 368 NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427
               C A N  G+      + +    + PP I+T    + +       +  C    +P P
Sbjct: 374 -VYQCEASNRHGTLLSNANIMIM---NFPPMILTENDEDYSAVEGKRVMMHCKVFSSPSP 429

Query: 428 IIAWYFEGEA-LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
            I W  +  +  +   R +V ++GTL +   +K D+G YTC A +  G    +  L V  
Sbjct: 430 TITWSKDDTSDSVDGPRFSVHDNGTLEIYRAEKEDAGPYTCFAKNTEGSSAINAMLSVKD 489

Query: 487 P 487
           P
Sbjct: 490 P 490



 Score =  113 bits (272), Expect = 3e-23
 Identities = 108/425 (25%), Positives = 176/425 (41%), Gaps = 41/425 (9%)

Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
           +G+ + LEC+   G P P V W K GQ L        H   G  L +    Q D G+Y C
Sbjct: 231 KGEDLNLECIAA-GFPTPQVEWVKMGQRLPTKATIESH---GKLLFVPTVEQEDGGKYMC 286

Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
            A+N  G       T+ +   P  ++ PE  ++  GS V  +C V G P P V WR +  
Sbjct: 287 KAKNTLGEAVHYF-TVTVEGPPEWVSEPESQLSMIGSDVLIKCSVSGTPQPTVTWRVNGN 345

Query: 241 G-GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
              + P    +VL D ++ L N   +D   Y CEA N  G + ++  + + + P + L+ 
Sbjct: 346 RLQDSPAPNRRVLGD-TIVLHNTKPSDSAVYQCEASNRHGTLLSNANIMIMNFPPMILTE 404

Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
           N  +  +  G      C     P PT+ WS +     +       ++   +V D  T L 
Sbjct: 405 NDEDYSAVEGKRVMMHCKVFSSPSPTITWSKDDTSDSV----DGPRF---SVHDNGT-LE 456

Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
           I   +K D+     C A N  GSS +   L+V     + P  I   P +  +   + A F
Sbjct: 457 IYRAEKEDA-GPYTCFAKNTEGSSAINAMLSV-----KDPTRIVEPPEDSRILKGTTAQF 510

Query: 418 PCTA----ICTPEPIIAWYFEGEALIQNHRRN---VTNDGTLVLKDLDKSDSGTYTCVA- 469
            C A      + +  I W  + + +  N+  N      DG L + ++   D G YTC+A 
Sbjct: 511 SCLAEYDKSFSNDFEILWEKDDKEIAVNYTENSRYFVEDGLLQIVNVSHLDKGVYTCLAR 570

Query: 470 SSRHGKYVWSGALLVDSPINPNI-----HFFRAADVSSLPGPPTKPITHNVTDTSVTLSW 524
           +   G    +  L++D P  P       H  ++  +  +PG       HN + T   + +
Sbjct: 571 TPMDGDKATALLLVIDVPDAPQYLVLSEHKSKSVKLKWIPGD-----DHNSSTTEFIIEY 625

Query: 525 SQNNK 529
            ++ +
Sbjct: 626 EESQR 630



 Score = 97.9 bits (233), Expect = 1e-18
 Identities = 79/271 (29%), Positives = 116/271 (42%), Gaps = 16/271 (5%)

Query: 31  LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
           + C   G+P P + W   G  +      +    G    L   H    SD+ VY CEA+N 
Sbjct: 326 IKCSVSGTPQPTVTWRVNGNRLQDSPAPNRRVLGDTIVL---HNTKPSDSAVYQCEASNR 382

Query: 91  YGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
           +GT  S NA + +         E +   SA +G  V++ C     SP P + W K+  + 
Sbjct: 383 HGTLLS-NANIMIMNFPPMILTENDEDYSAVEGKRVMMHC-KVFSSPSPTITWSKDDTSD 440

Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI-ATLKIHIKPYLITGP 208
             DG  R  + D G L I  A + DAG Y C A+N  G+  SAI A L +     ++  P
Sbjct: 441 SVDGP-RFSVHDNGTLEIYRAEKEDAGPYTCFAKNTEGS--SAINAMLSVKDPTRIVEPP 497

Query: 209 EDVVAQTGSSVTFQCRVGGDPLP----DVLWRRSAG--GGNMPLGRVKVLDDGSLRLDNV 262
           ED     G++  F C    D       ++LW +       N        ++DG L++ NV
Sbjct: 498 EDSRILKGTTAQFSCLAEYDKSFSNDFEILWEKDDKEIAVNYTENSRYFVEDGLLQIVNV 557

Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
              D+G Y+C A   +    A+  L V D P
Sbjct: 558 SHLDKGVYTCLARTPMDGDKATALLLVIDVP 588



 Score = 54.4 bits (125), Expect = 2e-05
 Identities = 49/177 (27%), Positives = 77/177 (43%), Gaps = 15/177 (8%)

Query: 14  IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFFLRAT 72
           + E   D +    +   ++C+   SPSP I W K       D  R S+   G L   RA 
Sbjct: 402 LTENDEDYSAVEGKRVMMHCKVFSSPSPTITWSKDDTSDSVDGPRFSVHDNGTLEIYRAE 461

Query: 73  HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL--EPESKQSAQGDTVVLECL 130
                 DAG Y C A N+ G++ + NA L V   ++  R+   PE  +  +G T    CL
Sbjct: 462 ----KEDAGPYTCFAKNTEGSS-AINAMLSV---KDPTRIVEPPEDSRILKGTTAQFSCL 513

Query: 131 PPRGSPEPN---VYWKKNGQTLLFD-GDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
                   N   + W+K+ + +  +  ++  + V+ G L I +    D G Y C+AR
Sbjct: 514 AEYDKSFSNDFEILWEKDDKEIAVNYTENSRYFVEDGLLQIVNVSHLDKGVYTCLAR 570


>UniRef50_UPI0000DB7802 Cluster: PREDICTED: similar to Neogenin
           precursor; n=1; Apis mellifera|Rep: PREDICTED: similar
           to Neogenin precursor - Apis mellifera
          Length = 1492

 Score =  132 bits (320), Expect = 4e-29
 Identities = 98/334 (29%), Positives = 139/334 (41%), Gaps = 16/334 (4%)

Query: 13  YIIEQPLDVTVARHQPATLNCRAGGS-PSPAIRWYKGG---VLVVSDTHRSILPAGGLFF 68
           Y   +P DV V +  PA L+C A  S   P I+W       +  + D++RS L  G L+ 
Sbjct: 26  YFTIEPQDVVVEQGNPARLDCEANSSFGKPNIQWRTDDGQPINFIGDSYRSQLSNGSLY- 84

Query: 69  LRATHGRVHSDAGVYWCEAT-NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
           + + +G      G Y C A+ +  G   SR AT+ +A L   F  EP+      G    L
Sbjct: 85  INSVYGTSLELTGSYQCLASVDDIGAIVSRIATIKIASL-PGFEKEPQDTMVYPGQIAYL 143

Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
            C     S    + W K+   L+   DSRM ++  G L I + +  D G Y+C A +   
Sbjct: 144 SCTLLATSSSLIIQWLKDEHPLIISMDSRMTILPSGALEIDNVKTEDVGSYRCNASSYGQ 203

Query: 188 TRESAIATLKI-------HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
            R S  A L +          P  I  P   V   GS++T +C   G P P +LW +   
Sbjct: 204 YRLSNKAQLGLLSDIDQESTPPVFIAKPLQQVIIEGSTITLECAANGYPKPSILWLKDGV 263

Query: 241 GGNMPL--GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
             ++     R   +   SL + NV   D G Y C AEN V  + A+  L V  PP     
Sbjct: 264 AIDLTSFKSRYSRIAASSLVISNVEEIDNGSYQCRAENEVEILDATADLIVQVPPRFIKK 323

Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332
           P            F C   G+P+P + W   G R
Sbjct: 324 PEDKIASENQDLEFECEIYGKPQPKITWLKNGER 357



 Score =  103 bits (248), Expect = 2e-20
 Identities = 99/394 (25%), Positives = 157/394 (39%), Gaps = 29/394 (7%)

Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN-GQTLLFDGDSRMHLVDGGNLVIQ 168
           F +EP+     QG+   L+C       +PN+ W+ + GQ + F GDS    +  G+L I 
Sbjct: 27  FTIEPQDVVVEQGNPARLDCEANSSFGKPNIQWRTDDGQPINFIGDSYRSQLSNGSLYIN 86

Query: 169 DARQTD---AGRYQCIAR-NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR 224
               T     G YQC+A  +  G   S IAT+KI   P     P+D +   G      C 
Sbjct: 87  SVYGTSLELTGSYQCLASVDDIGAIVSRIATIKIASLPGFEKEPQDTMVYPGQIAYLSCT 146

Query: 225 VGGDPLPDVL-WRRSAGGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVS 282
           +       ++ W +      + +  R+ +L  G+L +DNV   D G Y C A +S G   
Sbjct: 147 LLATSSSLIIQWLKDEHPLIISMDSRMTILPSGALEIDNVKTEDVGSYRCNA-SSYGQYR 205

Query: 283 AS-----GYLTVYD----PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRT 333
            S     G L+  D    PP     P    +  G+     C A G P+P++ W  +G   
Sbjct: 206 LSNKAQLGLLSDIDQESTPPVFIAKPLQQVIIEGSTITLECAANGYPKPSILWLKDGVAI 265

Query: 334 IIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
            +    SR  Y   A     + L I++ ++ D+  +  C A N          L V    
Sbjct: 266 DLTSFKSR--YSRIAA----SSLVISNVEEIDN-GSYQCRAENEVEILDATADLIV---- 314

Query: 394 DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLV 453
            + PP     P ++         F C     P+P I W   GE +  +    + N   L 
Sbjct: 315 -QVPPRFIKKPEDKIASENQDLEFECEIYGKPQPKITWLKNGERITLSAYWQIVNGYNLR 373

Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
           +  L   D+G + C+ ++  G    +  L ++ P
Sbjct: 374 INGLLPIDAGIFQCIGTNSAGTVQAAARLTINQP 407



 Score = 81.4 bits (192), Expect = 1e-13
 Identities = 56/182 (30%), Positives = 83/182 (45%), Gaps = 8/182 (4%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P  I +PL   +      TL C A G P P+I W K GV +   + +S         L  
Sbjct: 225 PVFIAKPLQQVIIEGSTITLECAANGYPKPSILWLKDGVAIDLTSFKSRYSRIAASSLVI 284

Query: 72  THGRVHSDAGVYWCEATNSYGTARSRNATLHVAV-LREEFRLEPESKQSAQGDTVVLECL 130
           ++     D G Y C A N        +AT  + V +   F  +PE K +++   +  EC 
Sbjct: 285 SNVE-EIDNGSYQCRAENE---VEILDATADLIVQVPPRFIKKPEDKIASENQDLEFEC- 339

Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
              G P+P + W KNG+ +     +   +V+G NL I      DAG +QCI  N+AGT +
Sbjct: 340 EIYGKPQPKITWLKNGERITL--SAYWQIVNGYNLRINGLLPIDAGIFQCIGTNSAGTVQ 397

Query: 191 SA 192
           +A
Sbjct: 398 AA 399



 Score = 62.9 bits (146), Expect = 5e-08
 Identities = 43/168 (25%), Positives = 76/168 (45%), Gaps = 5/168 (2%)

Query: 693 EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKW 752
           ++  L  YT+Y   +    +   G  S   V +T    P  PP N+ +  ++ T++ ++W
Sbjct: 637 DLIDLVPYTEYSIKVQAVNENGPGVFSRDIVVRTYSAQPTQPPHNVTVEPVSPTSIMIRW 696

Query: 753 SPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAA 812
            PP L+ QNGIITGY +     D  +    +A   T     S ++T L   V Y V+I A
Sbjct: 697 EPP-LEGQNGIITGYKIRYRRHDRASPPVNIA---TEGNQRSRVLTGLEKHVVYQVRICA 752

Query: 813 ETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETW 860
             + G GP+++ +           + +   P N    +++ D++   W
Sbjct: 753 LNVNGTGPWTEWIQIETYETESDENRVPNTPSNLRTKVMS-DYIQVFW 799



 Score = 46.0 bits (104), Expect = 0.006
 Identities = 38/131 (29%), Positives = 58/131 (44%), Gaps = 5/131 (3%)

Query: 694  ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNT--TTVHLK 751
            I  L+  T YEF +     K E   S     QT +  P   P N+ +  +    T+V L+
Sbjct: 944  INDLKPNTLYEFTVKLVKGKRESLWSMVVSNQTQEAAPSSAPRNLTIQSIEDRPTSVLLR 1003

Query: 752  WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811
            W PP+    NG ITGY +  +  +   ++  + I   +   T  I+  L   ++Y  +I 
Sbjct: 1004 WQPPKQP--NGPITGYIIFYSIDNTKWDRDWL-IEGVIGDKTEFIVKGLQPSMTYYFKIQ 1060

Query: 812  AETIIGLGPFS 822
            A    G GPFS
Sbjct: 1061 ARNSKGYGPFS 1071


>UniRef50_Q4TAD5 Cluster: Chromosome undetermined SCAF7373, whole
           genome shotgun sequence; n=28; Euteleostei|Rep:
           Chromosome undetermined SCAF7373, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 1090

 Score =  132 bits (320), Expect = 4e-29
 Identities = 132/546 (24%), Positives = 222/546 (40%), Gaps = 40/546 (7%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
           +T  E P  ++ P  +   R + A+L+C   GSP   + W K   L+       I+ AG 
Sbjct: 286 LTVQEPPSFVKTPSPLEGIRGKDASLHCEVAGSPPFQVTWSKEQKLLKDSRKYKIIKAGS 345

Query: 66  LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDT 124
              L      V  DAGVY C+ +N+ GT  +R A   +++      ++    QS   G+ 
Sbjct: 346 SVTLHIIKLEV-DDAGVYECQVSNNVGTESTRTA---ISLKEPPAFVKKLMDQSVMVGEQ 401

Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIA 182
           + L     +GS   ++ W ++   +L DGD+R    +    +L++  A    AG+Y C  
Sbjct: 402 LTLTA-TVKGSEPLDISWIQDNDHVLRDGDNRTITFEKSVVSLIVPQADSATAGKYTCRL 460

Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRS 238
            N +G   S +  + +     ++  PE +  QTG +V  +  + G       W    R  
Sbjct: 461 SNQSGVALS-VCHVTLLEPAAIVDSPESLNIQTGEAVALEVTICGSAELKTRWFKGDREL 519

Query: 239 AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSI 295
           + G    +   K +   +L++ +   AD GEY  E  N VG  S +  L V D   PPS 
Sbjct: 520 SAGNKYQMSSTKKV--ATLKIQSADKADAGEYKLEVSNHVGVASCTVTLAVSDKLIPPSF 577

Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
                  ++  G      C   G    T  W  +G    I  G+S D     +  D +  
Sbjct: 578 IRKLRDSHLVVGKSGDLDCKVIGSAPLTASWFHDGKE--IKSGLSYD----ISYVDNICK 631

Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
           L +      D      C A N AG+S     + V      PP  +    + ++LP  +++
Sbjct: 632 LRLQTVQTTDG-GRYTCKAANAAGTSETSASVNVA----EPPSFVETPEAQESLPGNNVS 686

Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRR---NVTND-GTLVLKDLDKSDSGTYTCVASS 471
              C  +    P+   +F G   + + R    ++ +D  TLVL  ++   +G YTC   +
Sbjct: 687 F--CAKVRGSSPLKVKWFRGSREMLHGRGCHISLKDDVATLVLNKVEMHHAGEYTCQVLN 744

Query: 472 RHGKYVWSGALLVDSPINPNIHFF-RAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530
             GK  +   L V  P    +HF  +  D+S   G P +          V ++W ++  +
Sbjct: 745 PVGKKSYPVYLSVREP----VHFVKKLRDISCEKGKPLRLEVSFAGTPRVNVTWKKDGGL 800

Query: 531 GSSSIL 536
             +S L
Sbjct: 801 IWASYL 806



 Score =  107 bits (257), Expect = 2e-21
 Identities = 116/485 (23%), Positives = 188/485 (38%), Gaps = 27/485 (5%)

Query: 13  YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRAT 72
           ++ + P    V  ++  +L CR   S S  I WYK    +    +  ++  G L      
Sbjct: 200 FVQKLPPTTFVKLNEGHSLECRVSSSQSLNICWYKNDHKITDGANTKLM-FGDLSARLQL 258

Query: 73  HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP 132
                 D+G+Y CE  N  G+A S ++ L V      F   P   +  +G    L C   
Sbjct: 259 LSAAFEDSGIYTCEVHNDAGSA-SCSSVLTVQE-PPSFVKTPSPLEGIRGKDASLHC-EV 315

Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT--DAGRYQCIARNAAGTRE 190
            GSP   V W K  Q LL D      +  G ++ +   +    DAG Y+C   N  GT E
Sbjct: 316 AGSPPFQVTWSKE-QKLLKDSRKYKIIKAGSSVTLHIIKLEVDDAGVYECQVSNNVGT-E 373

Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS-----AGGGNMP 245
           S    + +   P  +    D     G  +T    V G    D+ W +        G N  
Sbjct: 374 STRTAISLKEPPAFVKKLMDQSVMVGEQLTLTATVKGSEPLDISWIQDNDHVLRDGDNRT 433

Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
           +   K +   SL +     A  G+Y+C   N  G   +  ++T+ +P +I  SP S+N++
Sbjct: 434 ITFEKSVV--SLIVPQADSATAGKYTCRLSNQSGVALSVCHVTLLEPAAIVDSPESLNIQ 491

Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
           +G       T  G  E    W  +G+R +     + +KY  ++    V  L I   DK D
Sbjct: 492 TGEAVALEVTICGSAELKTRW-FKGDREL----SAGNKYQMSST-KKVATLKIQSADKAD 545

Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
           +         N+ G +     +T+   D   PP       +  L +       C  I + 
Sbjct: 546 A-GEYKLEVSNHVGVASC--TVTLAVSDKLIPPSFIRKLRDSHLVVGKSGDLDCKVIGSA 602

Query: 426 EPIIAWYFEGEAL---IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482
               +W+ +G+ +   +      V N   L L+ +  +D G YTC A++  G    S ++
Sbjct: 603 PLTASWFHDGKEIKSGLSYDISYVDNICKLRLQTVQTTDGGRYTCKAANAAGTSETSASV 662

Query: 483 LVDSP 487
            V  P
Sbjct: 663 NVAEP 667



 Score =  103 bits (247), Expect = 3e-20
 Identities = 114/482 (23%), Positives = 193/482 (40%), Gaps = 24/482 (4%)

Query: 5   YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
           +VT  E   I++ P  + +   +   L     GS     RW+KG   + +     +    
Sbjct: 472 HVTLLEPAAIVDSPESLNIQTGEAVALEVTICGSAELKTRWFKGDRELSAGNKYQMSSTK 531

Query: 65  GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQG 122
            +  L+       +DAG Y  E +N  G A S   TL V+  ++   F  +        G
Sbjct: 532 KVATLKIQSAD-KADAGEYKLEVSNHVGVA-SCTVTLAVSDKLIPPSFIRKLRDSHLVVG 589

Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCI 181
            +  L+C    GS      W  +G+ +       +  VD    L +Q  + TD GRY C 
Sbjct: 590 KSGDLDC-KVIGSAPLTASWFHDGKEIKSGLSYDISYVDNICKLRLQTVQTTDGGRYTCK 648

Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
           A NAAGT E++ A++ +   P  +  PE   +  G++V+F  +V G     V W R  G 
Sbjct: 649 AANAAGTSETS-ASVNVAEPPSFVETPEAQESLPGNNVSFCAKVRGSSPLKVKWFR--GS 705

Query: 242 GNMPLGR---VKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
             M  GR   + + DD  +L L+ V +   GEY+C+  N VG  S   YL+V +P     
Sbjct: 706 REMLHGRGCHISLKDDVATLVLNKVEMHHAGEYTCQVLNPVGKKSYPVYLSVREPVHFVK 765

Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
               ++ E G   R   +  G P   + W  +G   +I+        +     D   +L 
Sbjct: 766 KLRDISCEKGKPLRLEVSFAGTPRVNVTWKKDGG--LIWASY----LYNVITTDTSCILE 819

Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
           + ++D+ ++  T  C   N  G+      +++       P  +    S +     S+ + 
Sbjct: 820 VLNSDRMEAAGTYSCHLDNGVGNDVCEAHVSIL----ERPSFVERMESVEINEGDSL-LL 874

Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
            C    TPE  ++W+           ++ T      L+ L          VA ++ GK +
Sbjct: 875 RCLIEGTPEISVSWFKAEPVHFTRKLKDTTFTLGQPLQLLCTYSGSPRVSVAWTKDGKPI 934

Query: 478 WS 479
           W+
Sbjct: 935 WA 936



 Score = 66.9 bits (156), Expect = 3e-09
 Identities = 86/386 (22%), Positives = 146/386 (37%), Gaps = 37/386 (9%)

Query: 127 LECLPPRGSPEP-NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR----QTDAGRYQCI 181
           L CL     P P NV W +NG+ +       +   +      Q +R          Y C 
Sbjct: 122 LVCLVTGFYPAPVNVSWTRNGEEVTQGTSINVPYPNNEGTFTQISRLDFVPQQGDIYSCR 181

Query: 182 ARNAAGTRESAIATLKIHIKPYLITG-PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
            ++ A +     A  ++   P  +   P     +     + +CRV      ++ W ++  
Sbjct: 182 VQHPALSE----ADTRMWKPPQFVQKLPPTTFVKLNEGHSLECRVSSSQSLNICWYKNDH 237

Query: 241 GGNMPLGRVKVLDDGSLRLDNVILA--DEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
                     +  D S RL  +  A  D G Y+CE  N  G+ S S  LTV +PPS   +
Sbjct: 238 KITDGANTKLMFGDLSARLQLLSAAFEDSGIYTCEVHNDAGSASCSSVLTVQEPPSFVKT 297

Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
           P+ +    G  A   C   G P   + WS E             KY        VT+  I
Sbjct: 298 PSPLEGIRGKDASLHCEVAGSPPFQVTWSKEQKLL-----KDSRKYKIIKAGSSVTLHII 352

Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
               + D      C   N  G+   R  +++     + PP       +Q++ +       
Sbjct: 353 K--LEVDDAGVYECQVSNNVGTESTRTAISL-----KEPPAFVKKLMDQSVMVGEQLTLT 405

Query: 419 CTAICTPEPI-IAWYFEGEALIQN-HRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRH 473
            T +   EP+ I+W  + + ++++   R +T +    +L++   D + +G YTC  S++ 
Sbjct: 406 AT-VKGSEPLDISWIQDNDHVLRDGDNRTITFEKSVVSLIVPQADSATAGKYTCRLSNQS 464

Query: 474 G-------KYVWSGALLVDSPINPNI 492
           G         +   A +VDSP + NI
Sbjct: 465 GVALSVCHVTLLEPAAIVDSPESLNI 490



 Score = 56.4 bits (130), Expect = 4e-06
 Identities = 43/173 (24%), Positives = 74/173 (42%), Gaps = 13/173 (7%)

Query: 307  GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
            G   +  CT +G P  ++ W+ +G      P  +  +Y+     +   VL I ++D+  +
Sbjct: 908  GQPLQLLCTYSGSPRVSVAWTKDGK-----PIWASYQYNVRTT-NSSCVLEILNSDRPAA 961

Query: 367  RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
              T  C+  N AGS     ++++   + +  P  T  P    +  +   V     +   +
Sbjct: 962  GGTYACAISNGAGSDKCHARVSL---EHKTAPSFTRRPPESLVDSEGKTVKIEARVSGSQ 1018

Query: 427  PI-IAWYFEGEALIQNHRRN---VTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
            P+ + WY +   +   H      V N   L LK+  KS SG YTC AS+  GK
Sbjct: 1019 PLNVTWYKDNNEICSCHNYEMSFVNNLAILCLKNSSKSQSGVYTCSASNEAGK 1071



 Score = 46.4 bits (105), Expect = 0.005
 Identities = 41/164 (25%), Positives = 65/164 (39%), Gaps = 10/164 (6%)

Query: 134  GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNL--VIQDARQTDAGRYQCIARNAAGTRES 191
            GSP  +V W K+G+ +       +   +   +  ++   R    G Y C   N AG+ + 
Sbjct: 919  GSPRVSVAWTKDGKPIWASYQYNVRTTNSSCVLEILNSDRPAAGGTYACAISNGAGSDKC 978

Query: 192  -AIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGGGNMP 245
             A  +L+    P +    PE +V   G +V  + RV G    +V W +         N  
Sbjct: 979  HARVSLEHKTAPSFTRRPPESLVDSEGKTVKIEARVSGSQPLNVTWYKDNNEICSCHNYE 1038

Query: 246  LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
            +  V  L    L L N   +  G Y+C A N  G  S    +T+
Sbjct: 1039 MSFVNNL--AILCLKNSSKSQSGVYTCSASNEAGKASCLVSVTI 1080


>UniRef50_Q7QEI6 Cluster: ENSANGP00000020451; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000020451 - Anopheles gambiae
           str. PEST
          Length = 1228

 Score =  132 bits (319), Expect = 6e-29
 Identities = 133/508 (26%), Positives = 196/508 (38%), Gaps = 54/508 (10%)

Query: 12  PYIIEQPLDVT-----VARHQPATLNCRAGGSPSPAIRWYK-----GGVLVVS----DTH 57
           PY I QP+D T      +  +  TL+C AGG P+P   WYK       + V+        
Sbjct: 214 PYFIRQPVDTTYDTGKASITRDVTLSCLAGGYPTPRYTWYKEEYVKDNLTVIQIDPLRNA 273

Query: 58  RSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK 117
           R  +  G L   R +    + D G Y C A N+YG   S +  L+   + E F L+   +
Sbjct: 274 RHTVSGGNLIIHRPSQ---NLDQGTYHCTAQNAYGKILSESVQLNFGYILE-FNLQRAPE 329

Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR 177
           +  +     L C  P+  P+   YW +N        D R+ +   G+L        D   
Sbjct: 330 KGEENWGKALVCEEPQHYPDVKFYWSRNYFPNFVYEDQRVFVSHDGSLYFSSLEVMDRAN 389

Query: 178 YQCIARNAAGT--RESAIATLKIHIKPY---LI---TGPEDV--VAQTGSSVTFQCRVGG 227
           Y C   +      R      L +   P+   LI   T P+    V   G  V  +C   G
Sbjct: 390 YSCTVMSTVSDTGRNGPFFELSVSPSPHYQDLIFANTFPKAFPKVPLAGKDVRLECMTYG 449

Query: 228 DPLPDVLWRRSAGGGNMPLGRVKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASG 285
            P+    W R    GN+P  R+  L++ +  L + N  + D GEY C A N   +++ S 
Sbjct: 450 YPVASYNWTRR--NGNLP--RLSRLENYNRVLLIQNATVNDNGEYVCTARNGKKSITQSI 505

Query: 286 YLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR----TIIFPG-MS 340
           +L V   P+  +       +  +   F C A   P+    W   G      +    G ++
Sbjct: 506 FLNVQMEPNFTIPLRDRTKDFQSSVSFLCEAYAMPDVNYTWYKNGELMEEDSATGGGRLN 565

Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII 400
           RDKY    + D +  L IN  D  +      C A N     +   +L V S      P  
Sbjct: 566 RDKY---TIQDNL--LKINYLDPEEDNGMYQCKATNQLKGVYSAAQLRVLS----MKPSF 616

Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPE----PIIAWYFEGEALIQNHRRNVTNDGTLVLKD 456
              P      I S+A    T  C PE    P I W  +G  +     R +   GTL +  
Sbjct: 617 KKRPLESE--IYSIANGNTTIRCEPEAAPTPKIVWKKDGNVIGSGGHRKIYPTGTLHISP 674

Query: 457 LDKSDSGTYTCVASSRHGKYVWSGALLV 484
             + D GTYTC+AS+  G       L+V
Sbjct: 675 TSRDDEGTYTCIASNTQGMAESKARLIV 702



 Score = 83.4 bits (197), Expect = 3e-14
 Identities = 81/330 (24%), Positives = 127/330 (38%), Gaps = 41/330 (12%)

Query: 33  CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF----------FLRATHGRVHSDAGV 82
           C A   P     WYK G L+  D+       GG             L+  +     D G+
Sbjct: 534 CEAYAMPDVNYTWYKNGELMEEDS----ATGGGRLNRDKYTIQDNLLKINYLDPEEDNGM 589

Query: 83  YWCEATNSYGTARSRNATLHVAVLREEFR---LEPESKQSAQGDTVVLECLPPRGSPEPN 139
           Y C+ATN      S  A L V  ++  F+   LE E    A G+T +  C  P  +P P 
Sbjct: 590 YQCKATNQLKGVYSA-AQLRVLSMKPSFKKRPLESEIYSIANGNTTI-RC-EPEAAPTPK 646

Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
           + WKK+G  +   G  +++    G L I    + D G Y CIA N  G  ES    + + 
Sbjct: 647 IVWKKDGNVIGSGGHRKIYPT--GTLHISPTSRDDEGTYTCIASNTQGMAESKARLIVLQ 704

Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV--LWR-----------------RSAG 240
              +    P   + Q G  +  +C V  D L DV  +W                  R   
Sbjct: 705 ELRFTEQLPPKQIKQIGEMLFLRCDVTYDQLLDVAFVWTHNGQLLTGHDDADEQRLRQQP 764

Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
            G  P G    +   +L + N+ L D GEY C A++SV  + +   + +  PP    +  
Sbjct: 765 IGPAPDGARIRIHYNTLEVHNLTLVDGGEYECVAKSSVNRIVSRATVLIQGPPGAPGAVK 824

Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEG 330
            ++++                P +++++ G
Sbjct: 825 VIDIKKTEALLEWTNGNDNGRPILYYNILG 854



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 31/132 (23%), Positives = 58/132 (43%), Gaps = 7/132 (5%)

Query: 694  ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
            I  L   T Y   ++ +    EG  S   + +T    P  PP +++++ +N +T+ + W 
Sbjct: 1091 IVGLEPDTYYFVKVMAYNAAGEGPESERYLERTYRKAPQKPPSSVQIYGINPSTIKVTWR 1150

Query: 754  PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTT---VHQATSLIMTNLTSGVSYSVQI 810
                      + GY + + W     ++ M + N T   V +     + NLT G SY++++
Sbjct: 1151 YIAPSQDEEPVQGYKIRI-W---EKDQDMSSANDTVVLVGRKLEKYIDNLTPGKSYNLRV 1206

Query: 811  AAETIIGLGPFS 822
             A +  G G  S
Sbjct: 1207 LAFSNGGDGRMS 1218


>UniRef50_Q810U4 Cluster: Neuronal cell adhesion molecule precursor;
           n=48; Euteleostomi|Rep: Neuronal cell adhesion molecule
           precursor - Mus musculus (Mouse)
          Length = 1256

 Score =  132 bits (319), Expect = 6e-29
 Identities = 160/660 (24%), Positives = 260/660 (39%), Gaps = 63/660 (9%)

Query: 117 KQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAG 176
           K+  +G+ + LEC+   G P P +YW K    L    +   +      L I    + D+G
Sbjct: 274 KEELRGNVLSLECIA-EGLPTPIIYWIKEDGML--PANRTFYRNFKKTLQITHVSEADSG 330

Query: 177 RYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
            YQCIA+NA G     I+ + +   PY I  P+++V   G + T  CR  G+P P + W 
Sbjct: 331 NYQCIAKNALGAVHHTIS-VTVKAAPYWIVAPQNLVLSPGENGTLICRANGNPKPRISWL 389

Query: 237 RSAGGGNMPLGRV-KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-DPPS 294
            +     + L    + +D  ++   NV  +    Y C A N  G + A+ ++ V  +PP 
Sbjct: 390 TNGVPIEIALDDPSRKIDGDTIIFSNVQESSSAVYQCNASNKYGYLLANAFVNVLAEPPR 449

Query: 295 INLSPNSV-NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
           I  S N++  V +   A   C   G P PT+ W  +G +      +  D Y    + D  
Sbjct: 450 ILTSANTLYQVIANRPALLDCAFFGSPMPTIEW-FKGTKG---SALHEDIY---VLHDNG 502

Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413
           T L I    K DS  T  C A N  G +     L +     + P  I   P    +   S
Sbjct: 503 T-LEIPVAQK-DSTGTYTCVARNKLGMAKNEVHLEI-----KDPTRIIKQPEYAVVQRGS 555

Query: 414 MAVFPCTAIC--TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
              F C      T  P I W  +   L  N  R  T+   LV+ D+   D GTYTC A++
Sbjct: 556 KVSFECRVKHDHTLIPTIMWLKDNGEL-PNDERFSTDKDHLVVSDVKDDDGGTYTCTANT 614

Query: 472 RHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIG 531
                  S  L V +P  P       A +  +P PP      N  D SV L+W+  +   
Sbjct: 615 TLDSASASAVLRVVAP-TPT-----PAPIYDVPNPPFDLELTNQLDKSVQLTWTPGDD-N 667

Query: 532 SSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTEN 591
           +S I  + +E          +   ++  W   A            L P + Y F V  EN
Sbjct: 668 NSPITKFIIEY--------EDAMHDAGLWRHQAEVSGTQTTAQLKLSPYVNYSFRVMAEN 719

Query: 592 SHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKL 651
           S G S PS  S+                ++ + E   N +       +E    +   + +
Sbjct: 720 SIGRSMPSEASEQY--------------LTKAAEPDQNPMA------VEGLGTEPDNLVI 759

Query: 652 MWEILNFYYLEGLFIYFR-PLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPF 710
            W+ LN +   G  + ++        + E  +++ +N VS + ++    +  Y    +  
Sbjct: 760 TWKPLNGFQSNGPGLQYKVSWRQKDGDDEWTSVVVAN-VSKYIVSGTPTFVPY-LIKVQA 817

Query: 711 YKKFEGKPSNSRV-AQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNV 769
                  P  + V   + +D+P   P N+ + ++N+T   + W P   +   G + GY +
Sbjct: 818 LNDVGFAPEPAAVMGHSGEDLPMVAPGNVRVSVVNSTLAEVHWDPVPPKSVRGHLQGYRI 877



 Score =  113 bits (273), Expect = 2e-23
 Identities = 93/295 (31%), Positives = 132/295 (44%), Gaps = 21/295 (7%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSDTHRSILP 62
           VT   APY I  P ++ ++  +  TL CRA G+P P I W   GV   + + D  R I  
Sbjct: 349 VTVKAAPYWIVAPQNLVLSPGENGTLICRANGNPKPRISWLTNGVPIEIALDDPSRKI-D 407

Query: 63  AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK---QS 119
              + F         S + VY C A+N YG      A   V VL E  R+   +    Q 
Sbjct: 408 GDTIIFSNVQ----ESSSAVYQCNASNKYGYLL---ANAFVNVLAEPPRILTSANTLYQV 460

Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179
                 +L+C    GSP P + W K  +      D  + L D G L I  A++   G Y 
Sbjct: 461 IANRPALLDC-AFFGSPMPTIEWFKGTKGSALHEDIYV-LHDNGTLEIPVAQKDSTGTYT 518

Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRR 237
           C+ARN  G  ++ +  L+I     +I  PE  V Q GS V+F+CRV  D   +P ++W +
Sbjct: 519 CVARNKLGMAKNEV-HLEIKDPTRIIKQPEYAVVQRGSKVSFECRVKHDHTLIPTIMWLK 577

Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
               G +P       D   L + +V   D G Y+C A  ++ + SAS  L V  P
Sbjct: 578 D--NGELPNDERFSTDKDHLVVSDVKDDDGGTYTCTANTTLDSASASAVLRVVAP 630



 Score =  107 bits (258), Expect = 1e-21
 Identities = 182/813 (22%), Positives = 312/813 (38%), Gaps = 87/813 (10%)

Query: 30   TLNCRAGGSPSPAIRWYK-GGVLVVSDT-HRSILPAGGLFFLRATHGRVHSDAGVYWCEA 87
            +L C A G P+P I W K  G+L  + T +R+         L+ TH    +D+G Y C A
Sbjct: 283  SLECIAEGLPTPIIYWIKEDGMLPANRTFYRNFKKT-----LQITHVS-EADSGNYQCIA 336

Query: 88   TNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146
             N+ G       T+ V V    + +  P++   + G+   L C    G+P+P + W  NG
Sbjct: 337  KNALGAVHH---TISVTVKAAPYWIVAPQNLVLSPGENGTLICRA-NGNPKPRISWLTNG 392

Query: 147  QTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT 206
              +    D     +DG  ++  + +++ +  YQC A N  G    A A + +  +P  I 
Sbjct: 393  VPIEIALDDPSRKIDGDTIIFSNVQESSSAVYQCNASNKYGYL-LANAFVNVLAEPPRIL 451

Query: 207  GPEDVVAQTGSS--VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
               + + Q  ++      C   G P+P + W +   G  +      + D+G+L +     
Sbjct: 452  TSANTLYQVIANRPALLDCAFFGSPMPTIEWFKGTKGSALHEDIYVLHDNGTLEIPVAQK 511

Query: 265  ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPE--P 322
               G Y+C A N +G      +L + DP  I   P    V+ G+   F C         P
Sbjct: 512  DSTGTYTCVARNKLGMAKNEVHLEIKDPTRIIKQPEYAVVQRGSKVSFECRVKHDHTLIP 571

Query: 323  TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
            T+ W  +          S DK H          L ++D  K+D   T  C+A     S+ 
Sbjct: 572  TIMWLKDNGELPNDERFSTDKDH----------LVVSDV-KDDDGGTYTCTANTTLDSAS 620

Query: 383  VRGKLTVTSDDDRPPPI--ITNGPSNQTLP---IKSMAVFPCTAICTPEPIIAWYFEGE- 436
                L V +    P PI  + N P +  L     KS+ +          PI  +  E E 
Sbjct: 621  ASAVLRVVAPTPTPAPIYDVPNPPFDLELTNQLDKSVQLTWTPGDDNNSPITKFIIEYED 680

Query: 437  ----ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
                A +  H+  V+   T     L    + ++  +A +  G+ + S A           
Sbjct: 681  AMHDAGLWRHQAEVSGTQTTAQLKLSPYVNYSFRVMAENSIGRSMPSEA--------SEQ 732

Query: 493  HFFRAADVSSLP----GPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETL 548
            +  +AA+    P    G  T+P        ++ ++W   N   S+   G Q +V  R+  
Sbjct: 733  YLTKAAEPDQNPMAVEGLGTEP-------DNLVITWKPLNGFQSNG-PGLQYKVSWRQK- 783

Query: 549  SGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVG 608
             G++   +    VV+A   + + Y+V      + Y+  V+  N  G + P P +     G
Sbjct: 784  DGDDEWTS----VVVA---NVSKYIVSGTPTFVPYLIKVQALNDVGFA-PEPAAVMGHSG 835

Query: 609  DDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYF 668
            +D   +  G         R +++   + E +   P+  K+++   +    YY +      
Sbjct: 836  EDLPMVAPG-------NVRVSVVNSTLAE-VHWDPVPPKSVRGHLQGYRIYYWKTQSSSK 887

Query: 669  RPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLD 728
            R   +I    E K +      +   +  L+ Y+ Y   +     K EG  S  R   T +
Sbjct: 888  RNRRHI----EKKILTFQGTKTHGMLPGLQPYSHYALNVRVVNGKGEGPASTDRGFHTPE 943

Query: 729  DVPDGPPINIEMFILNTT--TVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN 786
             VP  P     + I+N T  ++ L+W PP     NGI+T Y +    ++       +   
Sbjct: 944  GVPSAPS---SLKIVNPTLDSLTLEWDPP--SHPNGILTEYILQYQPINSTHELGPLVDL 998

Query: 787  TTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819
                  T   + NL     Y     A+T +G G
Sbjct: 999  KIPANKTRWTLKNLNFSTRYKFYFYAQTSVGPG 1031



 Score = 64.1 bits (149), Expect = 2e-08
 Identities = 51/181 (28%), Positives = 77/181 (42%), Gaps = 10/181 (5%)

Query: 10  EAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGL 66
           + P I +Q P D  +   +   + C A G P P+  W + G    +  D   ++ P  G 
Sbjct: 38  QPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGSGT 97

Query: 67  FFLRA-THGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGD 123
             +   + G+  +  GVY C A N  G A S N  +  +   L  + RLEP   Q+  G 
Sbjct: 98  LVINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKERLEPIVLQN--GQ 155

Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIA 182
           ++VL C PP G P   ++W  N    L   + R+     G+L   +    D    Y C A
Sbjct: 156 SLVLPCRPPIGLPPAIIFWMDNSFQRLPQSE-RVSQGLNGDLYFSNVLPEDTREDYICYA 214

Query: 183 R 183
           R
Sbjct: 215 R 215



 Score = 52.4 bits (120), Expect = 7e-05
 Identities = 47/160 (29%), Positives = 68/160 (42%), Gaps = 9/160 (5%)

Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVI----QDARQTDAGR 177
           + +V++C   +G P P+  W +NG     D D  + +  G G LVI    +   +T  G 
Sbjct: 56  ENIVIQC-EAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGSGTLVINIMSEGKAETYEGV 114

Query: 178 YQCIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLW 235
           YQC ARN  G   S    ++    P +     E +V Q G S+   CR   G P   + W
Sbjct: 115 YQCTARNERGAAVSNNIVVRPSRSPLWTKERLEPIVLQNGQSLVLPCRPPIGLPPAIIFW 174

Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGE-YSCEA 274
             ++        RV    +G L   NV+  D  E Y C A
Sbjct: 175 MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYA 214


>UniRef50_UPI00006607E8 Cluster: Homolog of Homo sapiens
           "OTTHUMP00000065309; n=2; Clupeocephala|Rep: Homolog of
           Homo sapiens "OTTHUMP00000065309 - Takifugu rubripes
          Length = 1211

 Score =  132 bits (318), Expect = 7e-29
 Identities = 129/484 (26%), Positives = 194/484 (40%), Gaps = 37/484 (7%)

Query: 10  EAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGL 66
           + P I++Q   D  V       + C A G+  P   W + G    V  D   ++    G 
Sbjct: 9   QPPTIVKQSAKDYIVDPRDNIIIECEAKGNTLPTFSWRRNGKFFNVGKDPRVTMRKRSGT 68

Query: 67  FFLRATHG-RVHSDAGVYWCEATNSYGTARSRNATLHV--AVLREEFRLEPESKQSAQGD 123
             +    G R     G Y C A N  G A S    L V  A L  +  L+P      +G 
Sbjct: 69  LEISFRRGGRPEDYEGEYQCFANNELGVALSNKILLRVSKAPLWPKEVLDPVLVN--EGS 126

Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIA 182
            ++L C PP G P P ++W  N  T +   D R+ +   G+L   +    DA   Y+C A
Sbjct: 127 PLILPCNPPPGLPPPLIFWMDNTMTPIVQ-DKRVSMGLNGDLYFSNVMTKDALNEYKCNA 185

Query: 183 RN--AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGG----DPLPDVLWR 236
           R       ++     LK+     L      +++  GS  +     G     DP P + W 
Sbjct: 186 RCRLTQTIQQKNPFILKVQTSRKLPQSMPTLLSPVGSQSSKMVLRGQELLLDPTPSIKWY 245

Query: 237 RSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295
           R   GG++P  +VK  + + +L +  V   D GEY C A N +G+V  S  + V   P  
Sbjct: 246 RK--GGDLPERKVKFENFNKTLVVMGVSEEDAGEYVCMANNHLGSVRHSILVQVKAAPYW 303

Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF-PGMSRDKYHATAVFDGVT 354
              P ++ +      R  C A G P+P + W + G       P   R     T +F  V 
Sbjct: 304 LDKPTNLVLAPDEHGRLVCRANGNPKPNIQWLINGQPIETSPPNPGRQVLGDTIIFRSVQ 363

Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--K 412
           +          S     C+A N  G       ++V    D PP ++  GP NQ + +   
Sbjct: 364 M---------GSSAVYQCNASNQYGYLLANAFISVL---DMPPRML--GPKNQLIKVIEN 409

Query: 413 SMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
           +     C    +P P + W+  G+   +      V N+GTL +K     D GTYTCVA++
Sbjct: 410 THTFLDCPFFGSPLPDLRWFKNGQGSGVDGGHYTVHNNGTLEIKRARAEDEGTYTCVANN 469

Query: 472 RHGK 475
             GK
Sbjct: 470 LLGK 473



 Score =  112 bits (270), Expect = 5e-23
 Identities = 89/284 (31%), Positives = 135/284 (47%), Gaps = 15/284 (5%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWY-KGGVLVVSDTHRSILPAGGLFFL 69
           APY +++P ++ +A  +   L CRA G+P P I+W   G  +  S  +      G     
Sbjct: 300 APYWLDKPTNLVLAPDEHGRLVCRANGNPKPNIQWLINGQPIETSPPNPGRQVLGDTIIF 359

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTVVL 127
           R+        + VY C A+N YG   + NA + V  +     L P+++  +  +     L
Sbjct: 360 RSVQ---MGSSAVYQCNASNQYGYLLA-NAFISVLDMPPRM-LGPKNQLIKVIENTHTFL 414

Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
           +C P  GSP P++ W KNGQ    DG     + + G L I+ AR  D G Y C+A N  G
Sbjct: 415 DC-PFFGSPLPDLRWFKNGQGSGVDG-GHYTVHNNGTLEIKRARAEDEGTYTCVANNLLG 472

Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP-LP-DVLWRRSAGGGNMP 245
             E+ +  L++     +I  P+   A  GS+  F+C+V  DP LP  V W +     N+ 
Sbjct: 473 KAENQVR-LEVKEATRIIGVPQHQSAVRGSTARFKCQVKSDPSLPVTVTWTKDDKPLNVG 531

Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
               K  D+  L +  V   DEG Y+C  ++ + A SAS  LTV
Sbjct: 532 WRLRK--DEDLLSISAVNEGDEGMYTCTVKSEIDADSASARLTV 573



 Score =  103 bits (246), Expect = 4e-20
 Identities = 197/844 (23%), Positives = 310/844 (36%), Gaps = 87/844 (10%)

Query: 10  EAPYIIEQPLD-VTVARHQPATLNCRAG-GSPSPAIRWYKGGVL-VVSDTHRSILPAGGL 66
           +AP   ++ LD V V    P  L C    G P P I W    +  +V D   S+   G L
Sbjct: 108 KAPLWPKEVLDPVLVNEGSPLILPCNPPPGLPPPLIFWMDNTMTPIVQDKRVSMGLNGDL 167

Query: 67  FFLRATHGRVHSDA-GVYWCEAT-NSYGTARSRNA-TLHVAVLREEFRLEPE--SKQSAQ 121
           +F       +  DA   Y C A      T + +N   L V   R+  +  P   S   +Q
Sbjct: 168 YFSNV----MTKDALNEYKCNARCRLTQTIQQKNPFILKVQTSRKLPQSMPTLLSPVGSQ 223

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQ 179
              +VL        P P++ W + G  L      R    +  N  LV+    + DAG Y 
Sbjct: 224 SSKMVLRGQELLLDPTPSIKWYRKGGDL----PERKVKFENFNKTLVVMGVSEEDAGEYV 279

Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
           C+A N  G+   +I  +++   PY +  P ++V          CR  G+P P++ W  + 
Sbjct: 280 CMANNHLGSVRHSIL-VQVKAAPYWLDKPTNLVLAPDEHGRLVCRANGNPKPNIQWLING 338

Query: 240 GG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
                + P    +VL D ++   +V +     Y C A N  G + A+ +++V D P   L
Sbjct: 339 QPIETSPPNPGRQVLGD-TIIFRSVQMGSSAVYQCNASNQYGYLLANAFISVLDMPPRML 397

Query: 298 SPNS--VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
            P +  + V         C   G P P + W   G       G   D  H T   +G   
Sbjct: 398 GPKNQLIKVIENTHTFLDCPFFGSPLPDLRWFKNGQ------GSGVDGGHYTVHNNGT-- 449

Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
           L I      D   T  C A N  G +  + +L V     +    I   P +Q+    S A
Sbjct: 450 LEIKRARAEDE-GTYTCVANNLLGKAENQVRLEV-----KEATRIIGVPQHQSAVRGSTA 503

Query: 416 VFPCTAICTPE-PI-IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
            F C     P  P+ + W  + + L    R     D  L +  +++ D G YTC   S  
Sbjct: 504 RFKCQVKSDPSLPVTVTWTKDDKPLNVGWRLRKDED-LLSISAVNEGDEGMYTCTVKSEI 562

Query: 474 GKYVWSGALLV--DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIG 531
                S  L V    P+   I  F     +  P PP +    +    SV L+W   N+  
Sbjct: 563 DADSASARLTVLGHEPVFDMISGF----YTGCPDPPVELDLSDPAARSVRLTWIPGNE-H 617

Query: 532 SSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTEN 591
            S +  + V+        G         W  ++      + V+  L P + Y F V   N
Sbjct: 618 RSPVTHFLVQFEEDRWEPGQ--------WRNMSSYPGHLNSVILQLAPFVNYQFRVIAIN 669

Query: 592 SHGLSGPS-PVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIK 650
           S G S PS P     T G   + +  G     S +    I  + +++L       +    
Sbjct: 670 SVGQSEPSTPSPQYKTSGAAPDVIPRGLRGWGSMKDNMEITWEPLLDLERNGA--NLIYS 727

Query: 651 LMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPF 710
           L W   +              +N+T     K ++HS +           Y  YE  +   
Sbjct: 728 LWWRRKDM---------SEDWNNVTTAGN-KHMVHSTET----------YVPYEIKIQAG 767

Query: 711 YKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNV- 769
            +   G  SN  V  + +D P   P ++ +  +++T  ++ W P +L+   G    Y + 
Sbjct: 768 NEFGSGPVSNVVVGYSGEDTPTTAPTDLRVSKVDSTKAYIHWKPVDLKSVQGEFKEYRLY 827

Query: 770 ------VVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQ 823
                 +V  L+V   K +    +TV + +SL+   L         + A T    GP S 
Sbjct: 828 YWRDASLVPGLEVSKEKQIKGFYSTVSEPSSLLSELLPFSKYKMFMVVANTRYE-GPASN 886

Query: 824 KVYF 827
            V F
Sbjct: 887 TVEF 890



 Score = 49.6 bits (113), Expect = 5e-04
 Identities = 46/173 (26%), Positives = 80/173 (46%), Gaps = 11/173 (6%)

Query: 597 GPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEIL 656
           G  PVS+ V VG       E T  +  T+ R + + D     I   P+D K+++  ++  
Sbjct: 771 GSGPVSN-VVVGYSG----EDTPTTAPTDLRVSKV-DSTKAYIHWKPVDLKSVQGEFKEY 824

Query: 657 NFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEG 716
             YY     +   P   ++ E ++K    +       ++ L  ++KY+ F++    ++EG
Sbjct: 825 RLYYWRDASLV--PGLEVSKEKQIKGFYSTVSEPSSLLSELLPFSKYKMFMVVANTRYEG 882

Query: 717 KPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNV 769
             SN+    T + VPD P +   +   N  T+ LKW  P L+  NGI+ GY +
Sbjct: 883 PASNTVEFTTKEGVPDIPRL-FTINWKNLDTIQLKWGKP-LE-PNGILIGYQL 932


>UniRef50_UPI000065FAD3 Cluster: Homolog of Brachydanio rerio
           "Neural adhesion molecule L1.2.; n=1; Takifugu
           rubripes|Rep: Homolog of Brachydanio rerio "Neural
           adhesion molecule L1.2. - Takifugu rubripes
          Length = 1204

 Score =  131 bits (316), Expect = 1e-28
 Identities = 134/485 (27%), Positives = 202/485 (41%), Gaps = 60/485 (12%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
           + P + E P  +T        L C+A G+P P   W K GVL+ S  H   L A     L
Sbjct: 4   QPPVLSEVPESITAFSPVDIHLPCKAKGNPPPTFHWMKDGVLIRSGLHLGTLKAEEEEPL 63

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
           +   G        Y C A+N YGTA +++  + V       + +   K+S +G++++L C
Sbjct: 64  QQFEGH-------YRCYASNDYGTAMTQSVQVIVEAQPVLPKQQQVHKESYEGESIILSC 116

Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG----GNLVIQDARQTDAGRYQCIARNA 185
            PP  S  P ++W       +   +  +  +DG     NL+  D+R TD   Y C A+  
Sbjct: 117 NPPESSTPPVIHWMDKLMVHISQSERVLVGLDGKLYFSNLLRNDSR-TD---YMCNAQYL 172

Query: 186 AGTR---ESAIATLKIHI-------KPYLI--TGPED-VVAQTGSSVTFQCRVGGDPLPD 232
           A      ES I+   +         KP+    TGP   V+A  G  VT +C   G P P 
Sbjct: 173 AARTILTESVISLTVVPSNDVAQARKPHFFKHTGPHSSVLALRGHKVTLECIPKGLPTPK 232

Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
           V W++  G      G++    +     +++ L D+GEY C+A NS G  + S  +TV   
Sbjct: 233 VEWKKKDGRLGETSGQLDK-HNRWFHFESIGLNDDGEYECKAWNSHGFTTHSFTVTVEAA 291

Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
           P     P S     G   R  C A G P P++ WS+ G R I       ++    +V  G
Sbjct: 292 PYWVKKPASQLYSPGETVRLDCQAEGIPTPSITWSING-RNI----TEVEEEPRRSVSGG 346

Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
           V +L   D    D+     C A N  GS+ +   L V    + PP I+T+      +   
Sbjct: 347 VLIL--RDVVFADTA-VYQCEATNKHGSALLNTFLHVV---ELPPQILTSDGLLYRVTEG 400

Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
              +  C    +P P I                    GTLV+ ++D  D+G Y+C  S +
Sbjct: 401 RNILMDCEVFGSPRPHITC------------------GTLVISEVDHDDAGVYSC--SVK 440

Query: 473 HGKYV 477
           H   V
Sbjct: 441 HNNNV 445



 Score =  101 bits (241), Expect = 2e-19
 Identities = 85/297 (28%), Positives = 135/297 (45%), Gaps = 38/297 (12%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG---VLVVSDTHRSILP 62
           VT   APY +++P     +  +   L+C+A G P+P+I W   G     V  +  RS+  
Sbjct: 286 VTVEAAPYWVKKPASQLYSPGETVRLDCQAEGIPTPSITWSINGRNITEVEEEPRRSV-- 343

Query: 63  AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK-QSAQ 121
           +GG+  LR     V +D  VY CEATN +G+A   N  LHV  L  +         +  +
Sbjct: 344 SGGVLILRDV---VFADTAVYQCEATNKHGSALL-NTFLHVVELPPQILTSDGLLYRVTE 399

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
           G  ++++C    GSP P++                      G LVI +    DAG Y C 
Sbjct: 400 GRNILMDC-EVFGSPRPHITC--------------------GTLVISEVDHDDAGVYSCS 438

Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP-LP--DVLWRRS 238
            ++      S  A L+++ +  +   P+++    G++    C    DP LP   V+WRR 
Sbjct: 439 VKH--NNNVSINAHLEVYNRTVIPAPPQNLRFLRGTNALLTCGFYTDPRLPPAQVVWRRD 496

Query: 239 AGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
                G+    +  V +DG+L++ N+   D  +YSCE  + +  V A G +TV D P
Sbjct: 497 GHKLMGSETANKYSVFEDGTLKVSNIQFNDSAQYSCEVISLLDHVKAMGSITVVDRP 553



 Score = 98.7 bits (235), Expect = 8e-19
 Identities = 157/674 (23%), Positives = 252/674 (37%), Gaps = 102/674 (15%)

Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRY 178
           +G  V LEC+P +G P P V WKK    L   G++   L D  N     +     D G Y
Sbjct: 215 RGHKVTLECIP-KGLPTPKVEWKKKDGRL---GETSGQL-DKHNRWFHFESIGLNDDGEY 269

Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238
           +C A N+ G    +  T+ +   PY +  P   +   G +V   C+  G P P + W  S
Sbjct: 270 ECKAWNSHGFTTHSF-TVTVEAAPYWVKKPASQLYSPGETVRLDCQAEGIPTPSITW--S 326

Query: 239 AGGGNMPLGRV---KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPS 294
             G N+        + +  G L L +V+ AD   Y CEA N  G+   + +L V + PP 
Sbjct: 327 INGRNITEVEEEPRRSVSGGVLILRDVVFADTAVYQCEATNKHGSALLNTFLHVVELPPQ 386

Query: 295 INLSPNSV-NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
           I  S   +  V  G      C   G P P                      H T      
Sbjct: 387 ILTSDGLLYRVTEGRNILMDCEVFGSPRP----------------------HITC----- 419

Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413
             L I++ D +D+     CS V +  +  +   L V +    P P     P N      +
Sbjct: 420 GTLVISEVDHDDA-GVYSCS-VKHNNNVSINAHLEVYNRTVIPAP-----PQNLRFLRGT 472

Query: 414 MAVFPC---TAICTPEPIIAWYFEGEALIQNHRRN---VTNDGTLVLKDLDKSDSGTYTC 467
            A+  C   T    P   + W  +G  L+ +   N   V  DGTL + ++  +DS  Y+C
Sbjct: 473 NALLTCGFYTDPRLPPAQVVWRRDGHKLMGSETANKYSVFEDGTLKVSNIQFNDSAQYSC 532

Query: 468 VASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527
              S           L+D     ++    +  V   P PP       VTD ++TL+W+  
Sbjct: 533 EVIS-----------LLD-----HVKAMGSITVVDRPDPPKYLSLAEVTDHNLTLNWTPG 576

Query: 528 NKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIV 587
           +   +S ++ + VE F  E     +T      W  + +      +V  SL P  TY F V
Sbjct: 577 S-AHNSPMIDFIVE-FREE----QHTEGKKWKWEEMKKVPADVQHVQLSLRPFCTYRFRV 630

Query: 588 RTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNN-ILTDHIVELIEATPIDS 646
              N  G S PS  SD+                     YR +  + D     + +   D 
Sbjct: 631 IAVNEVGRSDPSEPSDT---------------------YRTSPAVPDRNPTGVRSESADP 669

Query: 647 KTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFF 706
            ++ + W+ ++  Y  G    +        + + +          F + +   YT +E  
Sbjct: 670 DSLVITWDEMDKMYHNGHGFLYEVSWREARKRDARWNSAEVKSPPFLVQNTGTYTPFEIK 729

Query: 707 LIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITG 766
           +        G      +  + +D P  PP  ++  ++N +TV +KW     Q   G++ G
Sbjct: 730 VKAVNSLGSGPAPEPEIGHSGEDKPAEPPTGVKTTVIN-STVTVKWD--AAQDVRGLLLG 786

Query: 767 YNVVVNWLDVPANK 780
           Y + +  L  P  +
Sbjct: 787 YKIHILRLGPPTER 800



 Score = 91.9 bits (218), Expect = 1e-16
 Identities = 99/383 (25%), Positives = 158/383 (41%), Gaps = 43/383 (11%)

Query: 21  VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
           V   R    TL C   G P+P + W K    +   + +  L     +F   + G   +D 
Sbjct: 211 VLALRGHKVTLECIPKGLPTPKVEWKKKDGRLGETSGQ--LDKHNRWFHFESIGL--NDD 266

Query: 81  GVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
           G Y C+A NS+G T  S   T+  A    +   +P S+  + G+TV L+C    G P P+
Sbjct: 267 GEYECKAWNSHGFTTHSFTVTVEAAPYWVK---KPASQLYSPGETVRLDC-QAEGIPTPS 322

Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
           + W  NG+ +    +     V GG L+++D    D   YQC A N  G+         + 
Sbjct: 323 ITWSINGRNITEVEEEPRRSVSGGVLILRDVVFADTAVYQCEATNKHGSALLNTFLHVVE 382

Query: 200 IKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLR 258
           + P ++T    +   T G ++   C V G P P +                     G+L 
Sbjct: 383 LPPQILTSDGLLYRVTEGRNILMDCEVFGSPRPHITC-------------------GTLV 423

Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC---T 315
           +  V   D G YSC  +++   VS + +L VY+   I   P ++    G  A  TC   T
Sbjct: 424 ISEVDHDDAGVYSCSVKHN-NNVSINAHLEVYNRTVIPAPPQNLRFLRGTNALLTCGFYT 482

Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
               P   + W  +G++  +    + +KY   +VF+  T L +++   NDS     C  +
Sbjct: 483 DPRLPPAQVVWRRDGHK--LMGSETANKY---SVFEDGT-LKVSNIQFNDSAQ-YSCEVI 535

Query: 376 NYAGSSFVRGKLTVTSDDDRPPP 398
           +        G +TV    DRP P
Sbjct: 536 SLLDHVKAMGSITVV---DRPDP 555



 Score = 50.8 bits (116), Expect = 2e-04
 Identities = 37/128 (28%), Positives = 58/128 (45%), Gaps = 5/128 (3%)

Query: 693 EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKW 752
           E+T LR ++ YE  +  +  K EG  S+     T +  P GPP ++ +   + T+V L W
Sbjct: 835 EVTGLRLFSLYELSVTAYNSKGEGPHSDPHRFSTPEGAP-GPPASLRLQSPSETSVILYW 893

Query: 753 SPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAA 812
           +PP     NGI+ GY  V+      AN   +    +    T   + +L     Y  ++ A
Sbjct: 894 APP--TEANGILLGY--VIQHKQEGANSESLLQMISDPSVTHFELHHLDPNSYYIFKVIA 949

Query: 813 ETIIGLGP 820
            T  G GP
Sbjct: 950 YTAAGEGP 957



 Score = 48.0 bits (109), Expect = 0.002
 Identities = 76/365 (20%), Positives = 133/365 (36%), Gaps = 36/365 (9%)

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG--GGNMPLGRVKVLDDGSLRL 259
           P L   PE + A +   +   C+  G+P P   W +        + LG +K  ++  L+ 
Sbjct: 6   PVLSEVPESITAFSPVDIHLPCKAKGNPPPTFHWMKDGVLIRSGLHLGTLKAEEEEPLQ- 64

Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES--GNVARFTCTAT 317
                  EG Y C A N  G         + +   +      V+ ES  G     +C   
Sbjct: 65  -----QFEGHYRCYASNDYGTAMTQSVQVIVEAQPVLPKQQQVHKESYEGESIILSCNPP 119

Query: 318 -GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
                P + W    ++ ++    S          DG   L  ++  +NDSR   +C+A  
Sbjct: 120 ESSTPPVIHWM---DKLMVHISQSE---RVLVGLDGK--LYFSNLLRNDSRTDYMCNAQY 171

Query: 377 YAGSSFVRGK---LTVTSDDD----RPPPIITN-GPSNQTLPIKSMAV-FPCTAICTPEP 427
            A  + +      LTV   +D    R P    + GP +  L ++   V   C     P P
Sbjct: 172 LAARTILTESVISLTVVPSNDVAQARKPHFFKHTGPHSSVLALRGHKVTLECIPKGLPTP 231

Query: 428 IIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD-S 486
            + W  +   L +   +   ++     + +  +D G Y C A + HG    S  + V+ +
Sbjct: 232 KVEWKKKDGRLGETSGQLDKHNRWFHFESIGLNDDGEYECKAWNSHGFTTHSFTVTVEAA 291

Query: 487 PI---NPNIHFFRAADVSSL----PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQ 539
           P     P    +   +   L     G PT  IT ++   ++T    +  +  S  +L  +
Sbjct: 292 PYWVKKPASQLYSPGETVRLDCQAEGIPTPSITWSINGRNITEVEEEPRRSVSGGVLILR 351

Query: 540 VEVFS 544
             VF+
Sbjct: 352 DVVFA 356



 Score = 36.7 bits (81), Expect = 3.9
 Identities = 25/79 (31%), Positives = 37/79 (46%), Gaps = 4/79 (5%)

Query: 689  VSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTV 748
            V+ FE+  L   + Y F +I +    EG P   R A  L+ V   PP N+ + +  TT+ 
Sbjct: 929  VTHFELHHLDPNSYYIFKVIAYTAAGEGPPIQLRGATMLEGV---PPSNVTI-VTGTTSF 984

Query: 749  HLKWSPPELQLQNGIITGY 767
            +L W P E    +G    Y
Sbjct: 985  NLSWVPEERNRNHGFHVEY 1003


>UniRef50_Q92823 Cluster: Neuronal cell adhesion molecule precursor;
           n=22; Euteleostomi|Rep: Neuronal cell adhesion molecule
           precursor - Homo sapiens (Human)
          Length = 1304

 Score =  131 bits (316), Expect = 1e-28
 Identities = 139/497 (27%), Positives = 201/497 (40%), Gaps = 47/497 (9%)

Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175
           +K+  +G+ + LEC+   G P P +YW K    L    +  ++      L I    + D+
Sbjct: 279 NKEELRGNVLSLECIA-EGLPTPIIYWAKEDGML--PKNRTVYKNFEKTLQIIHVSEADS 335

Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
           G YQCIA+NA G     I+ +++   PY IT P+++V   G   T  CR  G+P P + W
Sbjct: 336 GNYQCIAKNALGAIHHTIS-VRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISW 394

Query: 236 RRSAGGGNM-PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-DPP 293
             +     + P    + +D  ++   NV       Y C A N  G + A+ ++ V  +PP
Sbjct: 395 LTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPP 454

Query: 294 SINLSPNSV-NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA-VFD 351
            I    N++  V +   A   C   G P PT+ W         F G      H    V  
Sbjct: 455 RILTPANTLYQVIANRPALLDCAFFGSPLPTIEW---------FKGAKGSALHEDIYVLH 505

Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
               L I    K DS  T  C A N  G +     L +     + P  I   P    +  
Sbjct: 506 ENGTLEIPVAQK-DSTGTYTCVARNKLGMAKNEVHLEI-----KDPTWIVKQPEYAVVQR 559

Query: 412 KSMAVFPCTAIC--TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
            SM  F C      T    + W  +   L  + R  V  D  LV+ D+   DSGTYTCVA
Sbjct: 560 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH-LVVADVSDDDSGTYTCVA 618

Query: 470 SSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWS---Q 526
           ++       S  L V +P  P       A V  +P PP      +  D SV LSW+    
Sbjct: 619 NTTLDSVSASAVLSVVAP-TPT-----PAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDD 672

Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFI 586
           NN   +  I+ Y+ +   +  L  + T  +            QT   +K L P + Y F 
Sbjct: 673 NNSPITKFIIEYE-DAMHKPGLWHHQTEVSGT----------QTTAQLK-LSPYVNYSFR 720

Query: 587 VRTENSHGLSGPSPVSD 603
           V   NS G S PS  S+
Sbjct: 721 VMAVNSIGKSLPSEASE 737



 Score =  107 bits (256), Expect = 2e-21
 Identities = 91/290 (31%), Positives = 130/290 (44%), Gaps = 21/290 (7%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSDTHRSILPAGGLF 67
           APY I  P ++ ++  +  TL CRA G+P P I W   GV   +   D  R I   G   
Sbjct: 360 APYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKI--DGDTI 417

Query: 68  FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR-LEPESK--QSAQGDT 124
                  R    + VY C A+N YG      A   V VL E  R L P +   Q      
Sbjct: 418 IFSNVQER---SSAVYQCNASNEYGYLL---ANAFVNVLAEPPRILTPANTLYQVIANRP 471

Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
            +L+C    GSP P + W K  +      D  + L + G L I  A++   G Y C+ARN
Sbjct: 472 ALLDC-AFFGSPLPTIEWFKGAKGSALHEDIYV-LHENGTLEIPVAQKDSTGTYTCVARN 529

Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD--VLWRRSAGGG 242
             G  ++ +  L+I    +++  PE  V Q GS V+F+C+V  D      VLW +     
Sbjct: 530 KLGMAKNEV-HLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKD--NR 586

Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
            +P      +D   L + +V   D G Y+C A  ++ +VSAS  L+V  P
Sbjct: 587 ELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAP 636



 Score =  101 bits (241), Expect = 2e-19
 Identities = 183/808 (22%), Positives = 308/808 (38%), Gaps = 77/808 (9%)

Query: 30   TLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
            +L C A G P+P I W K  G+L  + T            L+  H    +D+G Y C A 
Sbjct: 289  SLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT----LQIIHVS-EADSGNYQCIAK 343

Query: 89   NSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
            N+ G       T+ V V    + +  P++   + G+   L C    G+P+P + W  NG 
Sbjct: 344  NALGAIHH---TISVRVKAAPYWITAPQNLVLSPGEDGTLICRA-NGNPKPRISWLTNGV 399

Query: 148  TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG 207
             +    D     +DG  ++  + ++  +  YQC A N  G    A A + +  +P  I  
Sbjct: 400  PIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYL-LANAFVNVLAEPPRILT 458

Query: 208  PEDVVAQTGSS--VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA 265
            P + + Q  ++      C   G PLP + W + A G  +      + ++G+L +      
Sbjct: 459  PANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKD 518

Query: 266  DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA--TGRPEPT 323
              G Y+C A N +G      +L + DP  I   P    V+ G++  F C          T
Sbjct: 519  STGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLT 578

Query: 324  MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383
            + W ++ NR +  P   R     T   D + V  ++D    D   T  C A     S   
Sbjct: 579  VLW-LKDNREL--PSDER----FTVDKDHLVVADVSD----DDSGTYTCVANTTLDSVSA 627

Query: 384  RGKLTVTSDDDRPPPI--ITNGPSNQTLP---IKSMAVFPCTAICTPEPIIAWYFEGEAL 438
               L+V +    P P+  + N P +  L     KS+ +          PI  +  E E  
Sbjct: 628  SAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDA 687

Query: 439  IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV-WSGALLVDSPINPNIHFFRA 497
            +  H+  + +  T V        SGT T  A  +   YV +S  ++  + I  ++    +
Sbjct: 688  M--HKPGLWHHQTEV--------SGTQT-TAQLKLSPYVNYSFRVMAVNSIGKSLPSEAS 736

Query: 498  ADVSSLPGPPTKPITH----NVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNT 553
                +    P K  T          ++ ++W   N   S+   G Q +V  R+   G++ 
Sbjct: 737  EQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNG-PGLQYKVSWRQK-DGDDE 794

Query: 554  PRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNS 613
              +    VV+A   + + Y+V      + Y+  V+  N  G + P P       G+D   
Sbjct: 795  WTS----VVVA---NVSKYIVSGTPTFVPYLIKVQALNDMGFA-PEPAVVMGHSGEDLPM 846

Query: 614  LWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDN 673
            +  G         R N++   + E +   P+  K+I+   +    YY +      R   +
Sbjct: 847  VAPG-------NVRVNVVNSTLAE-VHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRH 898

Query: 674  ITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDG 733
            I    E K +      +   +  L  ++ Y   +     K EG  S  RV  T + VP  
Sbjct: 899  I----EKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSA 954

Query: 734  PPINIEMFILNTT--TVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQ 791
            P     + I+N T  ++ L+W PP     NGI+T Y +    ++       +        
Sbjct: 955  PS---SLKIVNPTLDSLTLEWDPP--SHPNGILTEYTLKYQPINSTHELGPLVDLKIPAN 1009

Query: 792  ATSLIMTNLTSGVSYSVQIAAETIIGLG 819
             T   + NL     Y     A+T  G G
Sbjct: 1010 KTRWTLKNLNFSTRYKFYFYAQTSAGSG 1037



 Score = 68.1 bits (159), Expect = 1e-09
 Identities = 52/181 (28%), Positives = 79/181 (43%), Gaps = 10/181 (5%)

Query: 10  EAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGL 66
           + P I +Q P D  +   +   + C A G P P+  W + G    +  D   ++ P  G 
Sbjct: 44  QPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGT 103

Query: 67  FFLRA-THGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGD 123
             +   + G+  +  GVY C A N  G A S N  +  +   L  + +LEP + QS  G 
Sbjct: 104 LIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQS--GQ 161

Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIA 182
           ++VL C PP G P P ++W  N    L   + R+     G+L   +    D    Y C A
Sbjct: 162 SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSE-RVSQGLNGDLYFSNVLPEDTREDYICYA 220

Query: 183 R 183
           R
Sbjct: 221 R 221



 Score = 58.4 bits (135), Expect = 1e-06
 Identities = 67/305 (21%), Positives = 116/305 (38%), Gaps = 30/305 (9%)

Query: 200 IKPYLIT--GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257
           ++P  IT   P+D +     ++  QC   G P P   W R+    ++    +  +  G+ 
Sbjct: 43  VQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTG 102

Query: 258 RLDNVILAD------EGEYSCEAENSVGAVSASGYLT--VYDPPSINLSPNSVNVESGNV 309
            L   I+++      EG Y C A N  GA  ++  +      P         + ++SG  
Sbjct: 103 TLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQS 162

Query: 310 ARFTCTAT-GRPEPTMFWSVEGNRTI-----IFPGMSRDKYHATAV-----FDGVTVLTI 358
               C    G P P +FW     + +     +  G++ D Y +  +      D +     
Sbjct: 163 LVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARF 222

Query: 359 NDTDKNDSRNTIVCSAVNYAG-SSFVRGKLTVT------SDDDRPPPIIT--NGPSNQTL 409
           N T     +  I    ++    +  +   L+ T      S  +RPP  +T     SN+  
Sbjct: 223 NHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEE 282

Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
              ++    C A   P PII W  E   L +N       + TL +  + ++DSG Y C+A
Sbjct: 283 LRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIA 342

Query: 470 SSRHG 474
            +  G
Sbjct: 343 KNALG 347



 Score = 54.4 bits (125), Expect = 2e-05
 Identities = 56/218 (25%), Positives = 90/218 (41%), Gaps = 12/218 (5%)

Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVI----QDARQTDAGR 177
           + +V++C   +G P P+  W +NG     D D  + +  G G L+I    +   +T  G 
Sbjct: 62  ENIVIQC-EAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGV 120

Query: 178 YQCIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLW 235
           YQC ARN  G   S    ++    P +     E +  Q+G S+   CR   G P P + W
Sbjct: 121 YQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFW 180

Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGE-YSCEAE-NSVGAVSASGYLTVYDPP 293
             ++        RV    +G L   NV+  D  E Y C A  N    +     ++V    
Sbjct: 181 MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISV-KVI 239

Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGN 331
           S++   +++     +   F    + R  P  F + EGN
Sbjct: 240 SVDELNDTIAANLSD-TEFYGAKSSRERPPTFLTPEGN 276


>UniRef50_Q08CM9 Cluster: Zgc:152904; n=12; Euteleostomi|Rep:
           Zgc:152904 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 809

 Score =  130 bits (315), Expect = 2e-28
 Identities = 108/371 (29%), Positives = 165/371 (44%), Gaps = 31/371 (8%)

Query: 29  ATLNCRAGGSPSPAIRW-YKGGVLVVSDTHR-SILPAGGLFFLRATHGRVHSDAGVYWCE 86
           A + C    SP PA+ W YK   +      R  +LP   L  L+   G+  +D G Y CE
Sbjct: 101 AEVVCDVISSPVPAVSWFYKNREITSEPNSRFQVLPTNNLQILKV--GK--ADEGAYRCE 156

Query: 87  A-TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD---TVVLECLPPRGSPEPNVYW 142
           A   + G    R+  + V V        P+   +A  D   +V   C+   GSP+P V W
Sbjct: 157 ARVEARGEIDFRDIVVQVNV--PPVLSVPQQSFNATADYQESVTFTCVTS-GSPDPQVTW 213

Query: 143 KKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
              G  +       ++ ++GG   L +++ +QTD G Y C A N AG+ ES +  LK+ +
Sbjct: 214 YWKGHAIEHSEQYVLNTMNGGKSTLTVKNIKQTDGGPYMCRASNKAGSSESQLF-LKVFV 272

Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG------RVKVLD- 253
           +P+ IT   +V A  GS+    C   G+PLP++ WRR++ G +   G      RV+V   
Sbjct: 273 QPH-ITQLRNVTAVEGSAAMISCTAEGEPLPEISWRRASDGHSFTDGEKSKDGRVEVRGR 331

Query: 254 --DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVAR 311
                L +  V L+D G + CEA + +G    S +L +   P    + +      GN   
Sbjct: 332 HGKSMLTISGVQLSDWGRFDCEALSRIGGHQKSMFLDIEYAPKFQTNQSIFYSWEGNPVN 391

Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371
            +C     P  TM W  E   TI   G S  + H+T   DG ++L +      D      
Sbjct: 392 ISCEVKSNPAATMLWRRE-RFTISSQGTSNIRIHST---DGRSLLEVTPVSDRDF-GRYN 446

Query: 372 CSAVNYAGSSF 382
           C+A N  G+ +
Sbjct: 447 CTARNNIGARY 457



 Score =  109 bits (263), Expect = 3e-22
 Identities = 127/517 (24%), Positives = 213/517 (41%), Gaps = 37/517 (7%)

Query: 33  CRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSY 91
           C A G P  +I W+   G  ++S+  R I+   G+      +  +  +AG+Y C+A ++ 
Sbjct: 11  CTAIGEPV-SINWFSPQGERIISN-ERVIVHTEGVRSRLTIYNAIIENAGIYRCQAADAK 68

Query: 92  GTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
           G  +S+ AT+ + + ++  FR     ++  QGD   + C     SP P V W    + + 
Sbjct: 69  G--QSQEATVVLEIYQKLTFREVKTPQEFRQGDDAEVVC-DVISSPVPAVSWFYKNREIT 125

Query: 151 FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR-NAAGTRESAIATLKIHIKPYLITGPE 209
            + +SR  ++   NL I    + D G Y+C AR  A G  +     +++++ P L    +
Sbjct: 126 SEPNSRFQVLPTNNLQILKVGKADEGAYRCEARVEARGEIDFRDIVVQVNVPPVLSVPQQ 185

Query: 210 --DVVAQTGSSVTFQCRVGGDPLPDVLWR-RSAGGGNMPLGRVKVLDDG--SLRLDNVIL 264
             +  A    SVTF C   G P P V W  +     +     +  ++ G  +L + N+  
Sbjct: 186 SFNATADYQESVTFTCVTSGSPDPQVTWYWKGHAIEHSEQYVLNTMNGGKSTLTVKNIKQ 245

Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTM 324
            D G Y C A N  G+  +  +L V+  P I    N   VE G+ A  +CTA G P P +
Sbjct: 246 TDGGPYMCRASNKAGSSESQLFLKVFVQPHITQLRNVTAVE-GSAAMISCTAEGEPLPEI 304

Query: 325 FWSVEGNRTIIFPG-MSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383
            W    +      G  S+D         G ++LTI+    +D      C A++  G    
Sbjct: 305 SWRRASDGHSFTDGEKSKDGRVEVRGRHGKSMLTISGVQLSD-WGRFDCEALSRIGGH-- 361

Query: 384 RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR 443
             + ++  D +  P   TN     +     + +  C     P   + W  E   +     
Sbjct: 362 --QKSMFLDIEYAPKFQTNQSIFYSWEGNPVNI-SCEVKSNPAATMLWRRERFTISSQGT 418

Query: 444 RNV---TNDGTLVLK--DLDKSDSGTYTCVA----SSRHGKYVWSGALLVDSPINPNIHF 494
            N+   + DG  +L+   +   D G Y C A     +R+ +++ + A +  SP +  +  
Sbjct: 419 SNIRIHSTDGRSLLEVTPVSDRDFGRYNCTARNNIGARYQEFILAQADVPSSPYSVRMTA 478

Query: 495 F--RAADVS-----SLPGPPTKPITHNVTDTSVTLSW 524
              R A VS     S  G P      N  DTS    W
Sbjct: 479 VSQRMATVSFMKPDSHGGVPISFYIINYRDTSSAQEW 515



 Score = 87.4 bits (207), Expect = 2e-15
 Identities = 84/306 (27%), Positives = 129/306 (42%), Gaps = 30/306 (9%)

Query: 16  EQPLDVTVARHQPATLNCRAGGSPSPAIRWY-KGGVLVVSDTHRSILPAGGLFFLRATHG 74
           +Q  + T    +  T  C   GSP P + WY KG  +  S+ +      GG   L   + 
Sbjct: 184 QQSFNATADYQESVTFTCVTSGSPDPQVTWYWKGHAIEHSEQYVLNTMNGGKSTLTVKNI 243

Query: 75  RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRG 134
           +  +D G Y C A+N  G++ S+   L + V  +    +  +  + +G   ++ C    G
Sbjct: 244 K-QTDGGPYMCRASNKAGSSESQ---LFLKVFVQPHITQLRNVTAVEGSAAMISC-TAEG 298

Query: 135 SPEPNVYWKKNGQTLLF-DG----DSRMHLVDGGN----LVIQDARQTDAGRYQCIARNA 185
            P P + W++      F DG    D R+  V G +    L I   + +D GR+ C A + 
Sbjct: 299 EPLPEISWRRASDGHSFTDGEKSKDGRVE-VRGRHGKSMLTISGVQLSDWGRFDCEALSR 357

Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR------SA 239
            G  + ++  L I   P   T      +  G+ V   C V  +P   +LWRR      S 
Sbjct: 358 IGGHQKSM-FLDIEYAPKFQTNQSIFYSWEGNPVNISCEVKSNPAATMLWRRERFTISSQ 416

Query: 240 GGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
           G  N+   R+   D  S L +  V   D G Y+C A N++GA      L   D PS   S
Sbjct: 417 GTSNI---RIHSTDGRSLLEVTPVSDRDFGRYNCTARNNIGARYQEFILAQADVPS---S 470

Query: 299 PNSVNV 304
           P SV +
Sbjct: 471 PYSVRM 476



 Score = 70.5 bits (165), Expect = 3e-10
 Identities = 69/269 (25%), Positives = 112/269 (41%), Gaps = 22/269 (8%)

Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSC 272
           G S  F C   G+P+  + W    G   +   RV V  +G    L + N I+ + G Y C
Sbjct: 4   GESKFFTCTAIGEPV-SINWFSPQGERIISNERVIVHTEGVRSRLTIYNAIIENAGIYRC 62

Query: 273 EAENSVG-AVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGN 331
           +A ++ G +  A+  L +Y   +            G+ A   C     P P + W  + N
Sbjct: 63  QAADAKGQSQEATVVLEIYQKLTFREVKTPQEFRQGDDAEVVCDVISSPVPAVSWFYK-N 121

Query: 332 RTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA-VNYAGSSFVRGKLTVT 390
           R I     SR +   T   + + +L +   D+   R    C A V   G    R    + 
Sbjct: 122 REITSEPNSRFQVLPT---NNLQILKVGKADEGAYR----CEARVEARGEIDFRD---IV 171

Query: 391 SDDDRPPPIITNGPS-NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL--IQNHRRNVT 447
              + PP +     S N T   +    F C    +P+P + WY++G A+   + +  N  
Sbjct: 172 VQVNVPPVLSVPQQSFNATADYQESVTFTCVTSGSPDPQVTWYWKGHAIEHSEQYVLNTM 231

Query: 448 NDG--TLVLKDLDKSDSGTYTCVASSRHG 474
           N G  TL +K++ ++D G Y C AS++ G
Sbjct: 232 NGGKSTLTVKNIKQTDGGPYMCRASNKAG 260



 Score = 58.4 bits (135), Expect = 1e-06
 Identities = 59/221 (26%), Positives = 94/221 (42%), Gaps = 22/221 (9%)

Query: 15  IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLFFLRATH 73
           I Q  +VT      A ++C A G P P I W +       +D  +S     G   +R  H
Sbjct: 276 ITQLRNVTAVEGSAAMISCTAEGEPLPEISWRRASDGHSFTDGEKS---KDGRVEVRGRH 332

Query: 74  GRVH--------SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
           G+          SD G + CEA +  G    ++  L +     +F+       S +G+ V
Sbjct: 333 GKSMLTISGVQLSDWGRFDCEALSRIG-GHQKSMFLDIE-YAPKFQTNQSIFYSWEGNPV 390

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDS--RMHLVDGGNLV-IQDARQTDAGRYQCIA 182
            + C   + +P   + W++   T+   G S  R+H  DG +L+ +      D GRY C A
Sbjct: 391 NISC-EVKSNPAATMLWRRERFTISSQGTSNIRIHSTDGRSLLEVTPVSDRDFGRYNCTA 449

Query: 183 RNAAGTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTF 221
           RN  G R  E  +A   +   PY +      V+Q  ++V+F
Sbjct: 450 RNNIGARYQEFILAQADVPSSPYSVR--MTAVSQRMATVSF 488


>UniRef50_Q03696 Cluster: Neuronal-glial cell adhesion molecule
           precursor; n=2; Gallus gallus|Rep: Neuronal-glial cell
           adhesion molecule precursor - Gallus gallus (Chicken)
          Length = 1266

 Score =  130 bits (315), Expect = 2e-28
 Identities = 134/496 (27%), Positives = 194/496 (39%), Gaps = 37/496 (7%)

Query: 10  EAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR--SILPAGGL 66
           + P + E+P + + V       L C A G+P    RW +     V + H   S++P  G 
Sbjct: 34  QPPELTEEPPEQLVVFPSDDIVLKCVATGNPPVQYRWSREDQPFVPEEHGGVSVVPGSGT 93

Query: 67  FFLRAT-HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
             + AT   R+    G + C ATN+ GTA S  A +      +  + +    +  +GD V
Sbjct: 94  LVINATLAARLQ---GRFRCFATNALGTAVSPEANVIAENTPQWPKEKVTPVEVEEGDPV 150

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIARN 184
           VL C PP  +  P +YW  N   +    D R+ +   GNL   +A   D+   Y C A  
Sbjct: 151 VLPCDPPESAVPPKIYWL-NSDIVHIAQDERVSMGQDGNLYFSNAMVGDSHPDYICHAHF 209

Query: 185 AAGTRESAIATLKIHIKPY--------LITGPED----VVAQTGSSVTFQCRVGGDPLPD 232
                      L + + P          +  P D     +A  G SV  +C   G P P 
Sbjct: 210 LGPRTIIQKEPLDLRVAPSNAVRSRRPRLLLPRDPQTTTIALRGGSVVLECIAEGLPTPW 269

Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
           V WRR   G  +P G      + +LRL  V  +D+GEY C AEN  G    +  +TV   
Sbjct: 270 VRWRR-LNGPLLPGGVGNF--NKTLRLWGVTESDDGEYECVAENGRGTARGTHSVTVEAA 326

Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
           P     P S     G  AR  C   G+P P + WS+ G   I   G  R      A    
Sbjct: 327 PYWVRRPQSGVFGPGETARLDCEVGGKPRPQIQWSING-VPIEAAGAERRWLRGGA---- 381

Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
              L + +   NDS   + C A N  G       L V    + P  ++T       +   
Sbjct: 382 ---LVLPELRPNDSA-VLQCEARNRHGPLLANAFLHVV---ELPLRMLTADEQRYEVVEN 434

Query: 413 SMAVFPCTAICTPEPIIAWYFEG-EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
                 C     P P + W     E  +Q+ R  V  +G+L +  +   D G YTC+A +
Sbjct: 435 QTVFLHCRTFGAPAPNVEWLTPTLEPALQDDRSFVFTNGSLRVSAVRGGDGGVYTCMAQN 494

Query: 472 RHGKYVWSGALLVDSP 487
            H     +  L V +P
Sbjct: 495 AHSNGSLTALLEVRAP 510



 Score =  111 bits (266), Expect = 1e-22
 Identities = 93/310 (30%), Positives = 127/310 (40%), Gaps = 16/310 (5%)

Query: 18  PLDVTVA-RHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH--G 74
           P   T+A R     L C A G P+P +RW +         +  +LP G   F +     G
Sbjct: 244 PQTTTIALRGGSVVLECIAEGLPTPWVRWRR--------LNGPLLPGGVGNFNKTLRLWG 295

Query: 75  RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRG 134
              SD G Y C A N  GTAR  ++    A     +   P+S     G+T  L+C    G
Sbjct: 296 VTESDDGEYECVAENGRGTARGTHSVTVEAA--PYWVRRPQSGVFGPGETARLDC-EVGG 352

Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194
            P P + W  NG  +   G  R  L  GG LV+ + R  D+   QC ARN  G   +   
Sbjct: 353 KPRPQIQWSINGVPIEAAGAERRWL-RGGALVLPELRPNDSAVLQCEARNRHGPLLANAF 411

Query: 195 TLKIHIKPYLITGPEDVVAQTGSSVTF-QCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD 253
              + +   ++T  E       +   F  CR  G P P+V W        +   R  V  
Sbjct: 412 LHVVELPLRMLTADEQRYEVVENQTVFLHCRTFGAPAPNVEWLTPTLEPALQDDRSFVFT 471

Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313
           +GSLR+  V   D G Y+C A+N+    S +  L V  P  I+  P S   + G    F 
Sbjct: 472 NGSLRVSAVRGGDGGVYTCMAQNAHSNGSLTALLEVRAPTRISAPPRSATAKKGETVTFH 531

Query: 314 CTATGRPEPT 323
           C AT  P  T
Sbjct: 532 CGATFDPAVT 541



 Score =  103 bits (248), Expect = 2e-20
 Identities = 89/304 (29%), Positives = 125/304 (41%), Gaps = 17/304 (5%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAG 64
           VT   APY + +P        + A L+C  GG P P I+W   GV +  +   R  L  G
Sbjct: 321 VTVEAAPYWVRRPQSGVFGPGETARLDCEVGGKPRPQIQWSINGVPIEAAGAERRWLRGG 380

Query: 65  GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK-QSAQGD 123
            L           +D+ V  CEA N +G   + NA LHV  L        E + +  +  
Sbjct: 381 ALVLPELR----PNDSAVLQCEARNRHGPLLA-NAFLHVVELPLRMLTADEQRYEVVENQ 435

Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
           TV L C    G+P PNV W           D R  +   G+L +   R  D G Y C+A+
Sbjct: 436 TVFLHC-RTFGAPAPNVEWLTPTLEPALQ-DDRSFVFTNGSLRVSAVRGGDGGVYTCMAQ 493

Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPL---PDVLWRRSAG 240
           N A +  S  A L++     +   P    A+ G +VTF C    DP     ++ W R  G
Sbjct: 494 N-AHSNGSLTALLEVRAPTRISAPPRSATAKKGETVTFHCGATFDPAVTPGELRWLR--G 550

Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLSP 299
           G  +P    +      + + NV   DEG   C A   + +  A   L V   PPS +L  
Sbjct: 551 GQPLP-DDPRYSVAAEMTVSNVDYGDEGTIQCRASTPLDSAEAEAQLRVVGRPPSRDLQV 609

Query: 300 NSVN 303
             V+
Sbjct: 610 MEVD 613


>UniRef50_Q1JUB3 Cluster: L1-like cell adhesion molecule; n=1;
           Dugesia japonica|Rep: L1-like cell adhesion molecule -
           Dugesia japonica (Planarian)
          Length = 1351

 Score =  130 bits (314), Expect = 2e-28
 Identities = 126/485 (25%), Positives = 201/485 (41%), Gaps = 40/485 (8%)

Query: 12  PYIIEQPLDVTVARHQPAT-LNCRAGGSPSPAIRWYKGGVLV---VSDTHRSILPAGGLF 67
           P  + QP    V ++  A  L C A GSPSP   W K   +    ++    +  P  G  
Sbjct: 26  PSFVYQPNKNEVYQNLEALMLRCVATGSPSPTYTWLKNNKVFDFSINVGRYTKWPNEGTM 85

Query: 68  FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
            L   +     D G+Y C A NS+G A S  + +  A ++     +PE   + QG+ ++L
Sbjct: 86  ILALPND---DDDGIYQCIAENSHGKAYSIKSNVRRAEIQNFKNKDPEKITARQGEYLLL 142

Query: 128 ECLPPRGSPEPNVYWK--KNGQTLLFDGDSRMHLVDGGNLVIQD-ARQTDAGRYQCIARN 184
           +C  P   P P V W+  KNG   L    S+  +   GNL I     + D  ++ C   N
Sbjct: 143 KCEVPVCFPPPIVVWQKIKNGIAELIKESSKYVMDIDGNLYITGLTMEDDQAKFSCTVYN 202

Query: 185 -----AAGTRESAIATL--KIHIKPYL-ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
                    +E  I  +  + ++   L     + +  + G  +  +C + G P P+  W 
Sbjct: 203 QRMRMTKSDKEHWITVIPGQSNLPVVLRFRSLQPMNGRVGDKLVLRCILSGYPSPNYKW- 261

Query: 237 RSAGGGNMPLGRVKVLDD--GSLRLDN-VILADEGEYSCEAENSVG--AVSASGYLTVYD 291
              G     L R   + D  G++ + N V  AD+  + C  EN+V    +     + V  
Sbjct: 262 TVKGQDKSILERPNFITDAGGAILIINPVTTADQDTFQCTGENAVSNIPIVIDFQVNVEM 321

Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG-NRTIIFPGMSRDKYHATAVF 350
            P +    +  NV       F+C A GRP P + W+V G        G ++ K       
Sbjct: 322 TPILTTKLSDANVPYNGSHVFSCEAIGRPNPVITWTVNGVGLDTYLNGQNKRKI------ 375

Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
            G T+   N    + +     C+A NY G  +  G + V  D     P   NGP    + 
Sbjct: 376 -GNTIYLTNLLPGDHA--VFQCNASNYIGYDYSNGYINVLRD----KPEFINGPQATLIK 428

Query: 411 IKSM-AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
            ++  A   C A   P+ I+ W  +G   I   R  + ++G L++  L  +DSGTYTC A
Sbjct: 429 AENKPATINCQAFSAPKAIVTWTKDGFP-INGGRYMIQDNGDLLITKLITADSGTYTCTA 487

Query: 470 SSRHG 474
           ++ +G
Sbjct: 488 TNLYG 492



 Score = 90.2 bits (214), Expect = 3e-16
 Identities = 95/362 (26%), Positives = 145/362 (40%), Gaps = 29/362 (8%)

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
           GD +VL C+   G P PN  W   GQ   + +  + +    G  L+I      D   +QC
Sbjct: 242 GDKLVLRCILS-GYPSPNYKWTVKGQDKSILERPNFITDAGGAILIINPVTTADQDTFQC 300

Query: 181 IARNAAGTRESAIA-TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
              NA       I   + + + P L T   D       S  F C   G P P + W  + 
Sbjct: 301 TGENAVSNIPIVIDFQVNVEMTPILTTKLSDANVPYNGSHVFSCEAIGRPNPVITWTVNG 360

Query: 240 GGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-DPPSINL 297
            G +  L G+ K     ++ L N++  D   + C A N +G   ++GY+ V  D P    
Sbjct: 361 VGLDTYLNGQNKRKIGNTIYLTNLLPGDHAVFQCNASNYIGYDYSNGYINVLRDKPEFIN 420

Query: 298 SPNSVNVESGNV-ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
            P +  +++ N  A   C A   P+  + W+ +G     FP ++  +Y      D    L
Sbjct: 421 GPQATLIKAENKPATINCQAFSAPKAIVTWTKDG-----FP-INGGRYMIQDNGD----L 470

Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416
            I      DS  T  C+A N  GS  + G   V     R    +   P N  +       
Sbjct: 471 LITKLITADS-GTYTCTATNLYGS--ISGTCVVFV---RQRTELMIRPINTWVYFGQEVK 524

Query: 417 FPCTA----ICTPEPIIAWYFEGEAL-IQNHRRNVTN--DGTLVLKDLDKSDSGTYTCVA 469
           F CTA    + T    I WY +   + I  + R  TN  D +L++     +D+G YTC A
Sbjct: 525 FVCTAKTDRLETQNLKIVWYKDNSPITIGPYERTNTNLQDNSLIIMGAQTTDTGIYTCNA 584

Query: 470 SS 471
           ++
Sbjct: 585 TN 586



 Score = 64.1 bits (149), Expect = 2e-08
 Identities = 72/290 (24%), Positives = 111/290 (38%), Gaps = 17/290 (5%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFLR 70
           P +  +  D  V  +     +C A G P+P I W   GV L      ++    G   +L 
Sbjct: 323 PILTTKLSDANVPYNGSHVFSCEAIGRPNPVITWTVNGVGLDTYLNGQNKRKIGNTIYLT 382

Query: 71  ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ-SAQGDTVVLEC 129
                +  D  V+ C A+N  G   S N  ++V   + EF   P++    A+     + C
Sbjct: 383 ---NLLPGDHAVFQCNASNYIGYDYS-NGYINVLRDKPEFINGPQATLIKAENKPATINC 438

Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
                +P+  V W K+G  +      R  + D G+L+I      D+G Y C A N  G+ 
Sbjct: 439 -QAFSAPKAIVTWTKDGFPI---NGGRYMIQDNGDLLITKLITADSGTYTCTATNLYGS- 493

Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP----DVLWRRSAGGGNM- 244
            S    + +  +  L+  P +     G  V F C    D L      ++W +      + 
Sbjct: 494 ISGTCVVFVRQRTELMIRPINTWVYFGQEVKFVCTAKTDRLETQNLKIVWYKDNSPITIG 553

Query: 245 PLGRVKV-LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
           P  R    L D SL +      D G Y+C A N +    A   L V   P
Sbjct: 554 PYERTNTNLQDNSLIIMGAQTTDTGIYTCNATNGLDFDVAYATLIVQGKP 603



 Score = 62.5 bits (145), Expect = 7e-08
 Identities = 54/199 (27%), Positives = 83/199 (41%), Gaps = 13/199 (6%)

Query: 10  EAPYIIEQPLDVTV-ARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
           + P  I  P    + A ++PAT+NC+A  +P   + W K G   ++     I   G L  
Sbjct: 414 DKPEFINGPQATLIKAENKPATINCQAFSAPKAIVTWTKDG-FPINGGRYMIQDNGDLLI 472

Query: 69  LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
            +     + +D+G Y C ATN YG+  S    + V   R E  + P +     G  V   
Sbjct: 473 TKL----ITADSGTYTCTATNLYGSI-SGTCVVFVR-QRTELMIRPINTWVYFGQEVKFV 526

Query: 129 CLPPRGSPEP---NVYWKKNGQTLLFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCIARN 184
           C       E     + W K+   +      R +  +   +L+I  A+ TD G Y C A N
Sbjct: 527 CTAKTDRLETQNLKIVWYKDNSPITIGPYERTNTNLQDNSLIIMGAQTTDTGIYTCNATN 586

Query: 185 AAGTRESAIATLKIHIKPY 203
                + A ATL +  KP+
Sbjct: 587 GLDF-DVAYATLIVQGKPH 604



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 20/84 (23%), Positives = 33/84 (39%), Gaps = 4/84 (4%)

Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE----ALIQNHRRNVTNDGT 451
           PP  +     N+        +  C A  +P P   W    +    ++         N+GT
Sbjct: 25  PPSFVYQPNKNEVYQNLEALMLRCVATGSPSPTYTWLKNNKVFDFSINVGRYTKWPNEGT 84

Query: 452 LVLKDLDKSDSGTYTCVASSRHGK 475
           ++L   +  D G Y C+A + HGK
Sbjct: 85  MILALPNDDDDGIYQCIAENSHGK 108


>UniRef50_UPI0000E4747A Cluster: PREDICTED: similar to neuroglian;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           similar to neuroglian - Strongylocentrotus purpuratus
          Length = 762

 Score =  129 bits (312), Expect = 4e-28
 Identities = 107/334 (32%), Positives = 144/334 (43%), Gaps = 20/334 (5%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLR 70
           P I+EQP  VT  +  P TL CRA G+P P   W K G L  V    R+ L  G L    
Sbjct: 117 PSIVEQPESVTGDQRIPLTLPCRAIGTPEPTYYWEKDGSLFDVDSNDRTRLDGGNLVIES 176

Query: 71  ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC- 129
            T     +D G Y C A N  GTA S+     +A + +     P   Q +QG  + L C 
Sbjct: 177 LT----TADDGQYQCFANNRLGTAMSQKIRTSLAFMEQFVNTAPAMVQMSQGQPLKLRCG 232

Query: 130 -LP--PRGSPEPNVYWKKNGQTLLFDG-DSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
             P  P G+P P +YW          G D+R++    GNLV  +   +DA  Y C+A N 
Sbjct: 233 GSPGVPNGNPAPLIYWTDAAPKPTPIGYDARINQDLEGNLVFSNVIASDAKGYYCLAINN 292

Query: 186 AGT-RESAIATLKIHIKP------YLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
            G+ + S   TL +   P      +L + P    VA    S   +C   G P P + W+R
Sbjct: 293 VGSFQRSPKITLSVTDLPAVASAAHLDSHPAASEVANRTQSFKLKCIAFGYPTPVITWKR 352

Query: 238 SAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
                    GRV + + G +L +  V  +DEG Y+C A N+ G    S  +TV   P   
Sbjct: 353 GEEQLQSG-GRVSIEESGQALVISAVENSDEGTYTCVASNTGGDDEFSTVVTVESAPYFP 411

Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
             P       G      C + G P PT+ W V G
Sbjct: 412 APPFDETKGPGESFDIECRSEGVPPPTVEWLVNG 445



 Score =  107 bits (257), Expect = 2e-21
 Identities = 88/346 (25%), Positives = 146/346 (42%), Gaps = 30/346 (8%)

Query: 163 GNLVIQDARQTDAGRYQCIARNAAGTRES---------AIATLKIHIKPYLITGPEDVVA 213
           G+L+I + ++ D+G Y+C A N+   ++           + TL     P ++  PE V  
Sbjct: 69  GSLMINNVKKVDSGEYECTAENSIDGQDHEATGSATLIVLGTLLDDFPPSIVEQPESVTG 128

Query: 214 QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCE 273
                +T  CR  G P P   W +     ++       LD G+L ++++  AD+G+Y C 
Sbjct: 129 DQRIPLTLPCRAIGTPEPTYYWEKDGSLFDVDSNDRTRLDGGNLVIESLTTADDGQYQCF 188

Query: 274 AENSVGAVSASGYLT--VYDPPSINLSPNSVNVESGNVARFTCTAT-----GRPEPTMFW 326
           A N +G   +    T   +    +N +P  V +  G   +  C  +     G P P ++W
Sbjct: 189 ANNRLGTAMSQKIRTSLAFMEQFVNTAPAMVQMSQGQPLKLRCGGSPGVPNGNPAPLIYW 248

Query: 327 SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
                 T   P  +   Y A    D    L  ++   +D++    C A+N  GS F R  
Sbjct: 249 ------TDAAPKPTPIGYDARINQDLEGNLVFSNVIASDAKG-YYCLAINNVGS-FQRSP 300

Query: 387 LTVTSDDDRPPPI----ITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQN 441
               S  D P       + + P+   +  ++ +    C A   P P+I W    E L   
Sbjct: 301 KITLSVTDLPAVASAAHLDSHPAASEVANRTQSFKLKCIAFGYPTPVITWKRGEEQLQSG 360

Query: 442 HRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
            R ++   G  LV+  ++ SD GTYTCVAS+  G   +S  + V+S
Sbjct: 361 GRVSIEESGQALVISAVENSDEGTYTCVASNTGGDDEFSTVVTVES 406



 Score = 64.9 bits (151), Expect = 1e-08
 Identities = 64/236 (27%), Positives = 96/236 (40%), Gaps = 20/236 (8%)

Query: 254 DGSLRLDNVILADEGEYSCEAENSVGA----VSASGYL----TVYD--PPSINLSPNSVN 303
           +GSL ++NV   D GEY C AENS+       + S  L    T+ D  PPSI   P SV 
Sbjct: 68  EGSLMINNVKKVDSGEYECTAENSIDGQDHEATGSATLIVLGTLLDDFPPSIVEQPESVT 127

Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
            +        C A G PEPT +W  +G+   +F   S D+   T +  G  V+    T  
Sbjct: 128 GDQRIPLTLPCRAIGTPEPTYYWEKDGS---LFDVDSNDR---TRLDGGNLVIESLTTAD 181

Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
           +        + +  A S  +R  L          P +      Q L ++     P     
Sbjct: 182 DGQYQCFANNRLGTAMSQKIRTSLAFMEQFVNTAPAMVQMSQGQPLKLR-CGGSPGVPNG 240

Query: 424 TPEPIIAWYF---EGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476
            P P+I W     +   +  + R N   +G LV  ++  SD+  Y C+A +  G +
Sbjct: 241 NPAPLIYWTDAAPKPTPIGYDARINQDLEGNLVFSNVIASDAKGYYCLAINNVGSF 296



 Score = 60.5 bits (140), Expect = 3e-07
 Identities = 40/124 (32%), Positives = 58/124 (46%), Gaps = 11/124 (8%)

Query: 218 SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD--GSLRLDNVILADEGEYSCEAE 275
           S  F C   G P P + W  +  G  +  G    L++  GS+ ++NV   D GEY C AE
Sbjct: 475 SAKFICHFKGRPTPTITW--TFKGSVLTNGIKYTLNETEGSVVINNVKKVDSGEYECRAE 532

Query: 276 NSVGA----VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP---EPTMFWSV 328
           N++       + S  LTV    +I LSP ++ +  GN A F C         EP ++W  
Sbjct: 533 NAIDGEDYEATGSATLTVLGKTTIYLSPANLMIREGNTATFQCEIMYDEELIEPYVYWMK 592

Query: 329 EGNR 332
           +G R
Sbjct: 593 DGQR 596



 Score = 53.2 bits (122), Expect = 4e-05
 Identities = 43/145 (29%), Positives = 59/145 (40%), Gaps = 7/145 (4%)

Query: 4   DYVTSGEAPYIIEQPLDVTVA-RHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
           D      A ++   P    VA R Q   L C A G P+P I W +G   + S    SI  
Sbjct: 308 DLPAVASAAHLDSHPAASEVANRTQSFKLKCIAFGYPTPVITWKRGEEQLQSGGRVSIEE 367

Query: 63  AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122
           +G    + A     +SD G Y C A+N+ G      +T+        F   P  +    G
Sbjct: 368 SGQALVISAVE---NSDEGTYTCVASNTGGD--DEFSTVVTVESAPYFPAPPFDETKGPG 422

Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQ 147
           ++  +EC    G P P V W  NGQ
Sbjct: 423 ESFDIECRS-EGVPPPTVEWLVNGQ 446



 Score = 50.4 bits (115), Expect = 3e-04
 Identities = 27/96 (28%), Positives = 50/96 (52%), Gaps = 4/96 (4%)

Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE-- 190
           +G P P + W   G ++L +G         G++VI + ++ D+G Y+C A NA    +  
Sbjct: 483 KGRPTPTITWTFKG-SVLTNGIKYTLNETEGSVVINNVKKVDSGEYECRAENAIDGEDYE 541

Query: 191 -SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV 225
            +  ATL +  K  +   P +++ + G++ TFQC +
Sbjct: 542 ATGSATLTVLGKTTIYLSPANLMIREGNTATFQCEI 577



 Score = 42.7 bits (96), Expect = 0.059
 Identities = 36/134 (26%), Positives = 53/134 (39%), Gaps = 9/134 (6%)

Query: 21  VTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
           ++V     A   C   G P+P I W +KG VL     +      G +            D
Sbjct: 468 LSVVEDDSAKFICHFKGRPTPTITWTFKGSVLTNGIKYTLNETEGSVVINNVKK----VD 523

Query: 80  AGVYWCEATNSY-GTARSRNATLHVAVL-REEFRLEPESKQSAQGDTVVLEC--LPPRGS 135
           +G Y C A N+  G       +  + VL +    L P +    +G+T   +C  +     
Sbjct: 524 SGEYECRAENAIDGEDYEATGSATLTVLGKTTIYLSPANLMIREGNTATFQCEIMYDEEL 583

Query: 136 PEPNVYWKKNGQTL 149
            EP VYW K+GQ L
Sbjct: 584 IEPYVYWMKDGQRL 597



 Score = 37.5 bits (83), Expect = 2.2
 Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 1/58 (1%)

Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN-DGTLVLKDLDKSDSGTYTCVASS 471
           A F C     P P I W F+G  L    +  +   +G++V+ ++ K DSG Y C A +
Sbjct: 476 AKFICHFKGRPTPTITWTFKGSVLTNGIKYTLNETEGSVVINNVKKVDSGEYECRAEN 533


>UniRef50_Q4RZE9 Cluster: Chromosome undetermined SCAF14935, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF14935,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 735

 Score =  129 bits (312), Expect = 4e-28
 Identities = 86/275 (31%), Positives = 131/275 (47%), Gaps = 17/275 (6%)

Query: 29  ATLNCRAGGSPSPAIRWYKGG----VLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYW 84
           A L C+  G PSPAIRW K      V    D+  ++LP+G L   R        D+ +Y 
Sbjct: 20  ALLECKVSGEPSPAIRWQKNREDLPVTSEPDSQLAMLPSGSLQVSRVQP----PDSAMYR 75

Query: 85  CEATNSYGTARSRNATLHV----AVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
           C A N   +    +A L V     + R  +F   P    +  G  VVLEC    G P P+
Sbjct: 76  CLADNPGSSRTGADAELRVLPEPGLPRSLQFLQRPSRVTALLGSDVVLEC-SASGYPTPS 134

Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
           + W+K G+ L+     +  L+ G NL+I+     D+G Y C A N      SA A L + 
Sbjct: 135 IQWRK-GEELIQSWSKKYSLLVGSNLIIRSVTDDDSGSYSCTAANR-NQNISATAELSVL 192

Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL 259
           + P  +  P +  A   + V  +C V G+P P V W ++ G   +P    +++D  +L++
Sbjct: 193 VPPQFLNYPSNTYAYESTDVELECAVTGNPPPTVRWMKN-GEEVIPSDYFQMVDGSNLQI 251

Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
             ++ +DEG Y C AEN+ G+  A   L + +P S
Sbjct: 252 LGLVKSDEGFYQCVAENAAGSSQAMAQLLLREPVS 286



 Score = 94.7 bits (225), Expect = 1e-17
 Identities = 83/337 (24%), Positives = 138/337 (40%), Gaps = 31/337 (9%)

Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG---GNMPLGRVKVLDDGSLRLDN 261
           +T  + V +  G +   +C+V G+P P + W+++       + P  ++ +L  GSL++  
Sbjct: 6   VTPTKSVSSYLGDTALLECKVSGEPSPAIRWQKNREDLPVTSEPDSQLAMLPSGSLQVSR 65

Query: 262 VILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLS------PNSVNVESGNVARFTC 314
           V   D   Y C A+N   +   A   L V   P +  S      P+ V    G+     C
Sbjct: 66  VQPPDSAMYRCLADNPGSSRTGADAELRVLPEPGLPRSLQFLQRPSRVTALLGSDVVLEC 125

Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
           +A+G P P++ W  +G   I     S  K ++  V   + + ++ D D      +  C+A
Sbjct: 126 SASGYPTPSIQWR-KGEELI----QSWSKKYSLLVGSNLIIRSVTDDDSG----SYSCTA 176

Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFE 434
            N   +     +L+V       PP   N PSN      +     C     P P + W   
Sbjct: 177 ANRNQNISATAELSVLV-----PPQFLNYPSNTYAYESTDVELECAVTGNPPPTVRWMKN 231

Query: 435 GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHF 494
           GE +I +    + +   L +  L KSD G Y CVA +  G       LL+  P++P    
Sbjct: 232 GEEVIPSDYFQMVDGSNLQILGLVKSDEGFYQCVAENAAGSSQAMAQLLLREPVSP---- 287

Query: 495 FRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIG 531
              +  ++LP  P   +   V+   V LSW    + G
Sbjct: 288 ---SPGAALPSAPRDLVPVLVSSRFVRLSWRPPEESG 321



 Score = 91.9 bits (218), Expect = 1e-16
 Identities = 67/210 (31%), Positives = 103/210 (49%), Gaps = 15/210 (7%)

Query: 15  IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74
           +++P  VT        L C A G P+P+I+W KG  L+ S + +  L  G    +R+   
Sbjct: 107 LQRPSRVTALLGSDVVLECSASGYPTPSIQWRKGEELIQSWSKKYSLLVGSNLIIRSV-- 164

Query: 75  RVHSDAGVYWCEATNSYGTARSRNATLHVAVL-REEFRLEPESKQSAQGDTVVLECLPPR 133
               D+G Y C A N     ++ +AT  ++VL   +F   P +  + +   V LEC    
Sbjct: 165 -TDDDSGSYSCTAANRN---QNISATAELSVLVPPQFLNYPSNTYAYESTDVELECAVT- 219

Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES-A 192
           G+P P V W KNG+ ++        +VDG NL I    ++D G YQC+A NAAG+ ++ A
Sbjct: 220 GNPPPTVRWMKNGEEVI--PSDYFQMVDGSNLQILGLVKSDEGFYQCVAENAAGSSQAMA 277

Query: 193 IATLKIHIKP----YLITGPEDVVAQTGSS 218
              L+  + P     L + P D+V    SS
Sbjct: 278 QLLLREPVSPSPGAALPSAPRDLVPVLVSS 307



 Score = 67.3 bits (157), Expect = 2e-09
 Identities = 37/131 (28%), Positives = 61/131 (46%), Gaps = 5/131 (3%)

Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751
           +++  L K+T+Y   ++   +      + +    T  DVP  PP NI + ++ + ++ + 
Sbjct: 493 YKMDGLNKFTEYTVRVLALNRYGPSPATEAAGVTTHSDVPSAPPQNITLEVVLSRSIKVL 552

Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811
           W PP    QNG+IT Y +         +K  +  N   +     + T L  G  YS Q+A
Sbjct: 553 WQPPPRSSQNGVITAYKIKYRKTGRRGDKEAIEPNNFWY-----LFTGLEKGSQYSFQVA 607

Query: 812 AETIIGLGPFS 822
           A T  G GPFS
Sbjct: 608 AMTANGTGPFS 618



 Score = 45.6 bits (103), Expect = 0.008
 Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 4/85 (4%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P  +  P +          L C   G+P P +RW K G  V+   +  ++    L  L  
Sbjct: 195 PQFLNYPSNTYAYESTDVELECAVTGNPPPTVRWMKNGEEVIPSDYFQMVDGSNLQIL-- 252

Query: 72  THGRVHSDAGVYWCEATNSYGTARS 96
             G V SD G Y C A N+ G++++
Sbjct: 253 --GLVKSDEGFYQCVAENAAGSSQA 275



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 40/170 (23%), Positives = 70/170 (41%), Gaps = 18/170 (10%)

Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDD--VPDGPPINIEMFILNTTTVHLK 751
           +++L+    Y F +I +     G+ S      T  D  VP     ++ +  L+ T+V + 
Sbjct: 399 VSNLKPEETYSFRVIAYNDVGPGESSAPLKITTKPDLQVPSRAE-SLRLVALSPTSVQVS 457

Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSM-VAINTTVHQATSLIMTNLTSGVSYSVQI 810
           W PP     NG I GY ++  W + P+ K   V +N+  ++     M  L     Y+V++
Sbjct: 458 WEPP--SHPNGPILGYRLL--WTESPSGKEQSVEVNSLTYK-----MDGLNKFTEYTVRV 508

Query: 811 AAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETW 860
            A    G  P ++       S     D+ S  P N  + +V    +   W
Sbjct: 509 LALNRYGPSPATEAAGVTTHS-----DVPSAPPQNITLEVVLSRSIKVLW 553


>UniRef50_UPI000065D5B9 Cluster: Contactin-4 precursor
           (Brain-derived immunoglobulin superfamily protein 2)
           (BIG-2).; n=3; Euteleostomi|Rep: Contactin-4 precursor
           (Brain-derived immunoglobulin superfamily protein 2)
           (BIG-2). - Takifugu rubripes
          Length = 1100

 Score =  128 bits (310), Expect = 7e-28
 Identities = 123/429 (28%), Positives = 169/429 (39%), Gaps = 38/429 (8%)

Query: 32  NCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
           +C A G P P  RW      +      R  L  G L   R        D G+Y C  +NS
Sbjct: 31  SCEAQGHPPPFYRWKLNDSFIHPRPGSRYSLVGGNLHISRLNKDE---DVGIYQCLGSNS 87

Query: 91  YGTARSRNATLHVAVLREEFRLEPESK-QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
           +GT  SR A+LHVA L E+F+    +  +  +G  VVL C PP  S E    W  N    
Sbjct: 88  FGTIVSREASLHVAYL-EDFKTHRRNPVRVREGQGVVLLCGPPSHSGELTFKWIFNEYPS 146

Query: 150 LFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGTRESAIA-----TLKI----- 198
               D+R  +    GNL I     +D G Y C+  N   T+ S         L++     
Sbjct: 147 FVTQDTRRFVSQKTGNLYIAKVDPSDVGNYTCVVTNTV-TKSSVQGPPTPLVLRVDGVMG 205

Query: 199 HIKPYL-ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD--DG 255
             +P + +  PE V     S+V  +C   G+P+P + WRR  G      GR   ++   G
Sbjct: 206 EYEPKIEVQFPEVVPVAKSSTVKLECFALGNPVPTISWRREGGAS---FGRKVDVNKASG 262

Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315
            L +    + D G Y C AENS G     G L+ Y  P +   P  V     +   + C 
Sbjct: 263 VLEIPYFQMEDAGVYECVAENSRGRNLVKGKLSFYAAPQLTEKPQDVQKTIDDTLVWECK 322

Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
           A G+P+P+  W   G           D+         +T L + D           C A 
Sbjct: 323 ANGKPKPSYRWLKNGEPL----DHMEDRLQVNNGVLNITSLNLADI------GMYQCVAE 372

Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFE 434
           N  G  F   +L V +     P    N    QTL  +   V   C    +P  II+W   
Sbjct: 373 NRHGRVFTNAELRVVA---IAPDFSQNLLKAQTLARQGGDVLIECKPRMSPRGIISWRKG 429

Query: 435 GEALIQNHR 443
            EAL +NHR
Sbjct: 430 KEALRENHR 438



 Score =  103 bits (247), Expect = 3e-20
 Identities = 103/376 (27%), Positives = 148/376 (39%), Gaps = 33/376 (8%)

Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA-RQTDAGRYQCIAR 183
           VV  C   +G P P   WK N   +     SR  LV GGNL I    +  D G YQC+  
Sbjct: 28  VVFSC-EAQGHPPPFYRWKLNDSFIHPRPGSRYSLV-GGNLHISRLNKDEDVGIYQCLGS 85

Query: 184 NAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRV---GGDPLPDVLWRRSA 239
           N+ GT  S  A+L + +++ +       V  + G  V   C      G+     ++    
Sbjct: 86  NSFGTIVSREASLHVAYLEDFKTHRRNPVRVREGQGVVLLCGPPSHSGELTFKWIFNEYP 145

Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV---------- 289
                   R      G+L +  V  +D G Y+C   N+V   S  G  T           
Sbjct: 146 SFVTQDTRRFVSQKTGNLYIAKVDPSDVGNYTCVVTNTVTKSSVQGPPTPLVLRVDGVMG 205

Query: 290 -YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
            Y+P      P  V V   +  +  C A G P PT+ W  EG  +    G   D   A+ 
Sbjct: 206 EYEPKIEVQFPEVVPVAKSSTVKLECFALGNPVPTISWRREGGASF---GRKVDVNKASG 262

Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408
           V + +    + D    +      C A N  G + V+GKL+  +      P +T  P +  
Sbjct: 263 VLE-IPYFQMEDAGVYE------CVAENSRGRNLVKGKLSFYA-----APQLTEKPQDVQ 310

Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468
             I    V+ C A   P+P   W   GE L     R   N+G L +  L+ +D G Y CV
Sbjct: 311 KTIDDTLVWECKANGKPKPSYRWLKNGEPLDHMEDRLQVNNGVLNITSLNLADIGMYQCV 370

Query: 469 ASSRHGKYVWSGALLV 484
           A +RHG+   +  L V
Sbjct: 371 AENRHGRVFTNAELRV 386



 Score = 74.9 bits (176), Expect = 1e-11
 Identities = 65/225 (28%), Positives = 94/225 (41%), Gaps = 11/225 (4%)

Query: 15  IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74
           ++ P  V VA+     L C A G+P P I W + G          +  A G+  L   + 
Sbjct: 213 VQFPEVVPVAKSSTVKLECFALGNPVPTISWRREGGASFG-RKVDVNKASGV--LEIPYF 269

Query: 75  RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRG 134
           ++  DAGVY C A NS G    +      A    +   +P+  Q    DT+V EC    G
Sbjct: 270 QM-EDAGVYECVAENSRGRNLVKGKLSFYAA--PQLTEKPQDVQKTIDDTLVWEC-KANG 325

Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194
            P+P+  W KNG+ L    D R+  V+ G L I      D G YQC+A N  G   +   
Sbjct: 326 KPKPSYRWLKNGEPLDHMED-RLQ-VNNGVLNITSLNLADIGMYQCVAENRHGRVFTNAE 383

Query: 195 TLKIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
              + I P           +A+ G  V  +C+    P   + WR+
Sbjct: 384 LRVVAIAPDFSQNLLKAQTLARQGGDVLIECKPRMSPRGIISWRK 428



 Score = 60.5 bits (140), Expect = 3e-07
 Identities = 44/141 (31%), Positives = 63/141 (44%), Gaps = 8/141 (5%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
           AP + E+P DV           C+A G P P+ RW K G  +     R  +  G    L 
Sbjct: 299 APQLTEKPQDVQKTIDDTLVWECKANGKPKPSYRWLKNGEPLDHMEDRLQVNNG---VLN 355

Query: 71  ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEF--RLEPESKQSAQGDTVVLE 128
            T   + +D G+Y C A N +G   + NA L V  +  +F   L      + QG  V++E
Sbjct: 356 ITSLNL-ADIGMYQCVAENRHGRVFT-NAELRVVAIAPDFSQNLLKAQTLARQGGDVLIE 413

Query: 129 CLPPRGSPEPNVYWKKNGQTL 149
           C  PR SP   + W+K  + L
Sbjct: 414 C-KPRMSPRGIISWRKGKEAL 433



 Score = 54.0 bits (124), Expect = 2e-05
 Identities = 27/73 (36%), Positives = 39/73 (53%)

Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESG 307
           +V VLD+GSLR+ NV   D+G Y+C A N  G  S++G L V +P +I      ++V  G
Sbjct: 488 QVTVLDNGSLRISNVTRLDDGLYTCVARNQFGVASSAGSLLVKEPTAITSPAGHLDVTVG 547

Query: 308 NVARFTCTATGRP 320
                 C  +  P
Sbjct: 548 ESIVLPCQVSHDP 560



 Score = 53.2 bits (122), Expect = 4e-05
 Identities = 42/143 (29%), Positives = 67/143 (46%), Gaps = 10/143 (6%)

Query: 159 LVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT-GS 217
           ++D G+L I +  + D G Y C+ARN  G   SA  +L +  +P  IT P   +  T G 
Sbjct: 491 VLDNGSLRISNVTRLDDGLYTCVARNQFGVASSA-GSLLVK-EPTAITSPAGHLDVTVGE 548

Query: 218 SVTFQCRVGGDPLPDV--LW---RRSAGGGNMPLGRVKV--LDDGSLRLDNVILADEGEY 270
           S+   C+V  DP  ++   W    +    GN+     KV     G + + N+     G+Y
Sbjct: 549 SIVLPCQVSHDPTLELKFTWFFNEQLIHFGNLWAFFEKVGGRSSGDIMIRNIQPKHAGKY 608

Query: 271 SCEAENSVGAVSASGYLTVYDPP 293
           +C  +  V +VS +  + V  PP
Sbjct: 609 TCAVQTKVDSVSIATDVVVRGPP 631



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 16/42 (38%), Positives = 27/42 (64%)

Query: 446 VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
           V ++G+L + ++ + D G YTCVA ++ G    +G+LLV  P
Sbjct: 491 VLDNGSLRISNVTRLDDGLYTCVARNQFGVASSAGSLLVKEP 532


>UniRef50_UPI0000E4A418 Cluster: PREDICTED: similar to axonin-1;
           n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
           similar to axonin-1 - Strongylocentrotus purpuratus
          Length = 1053

 Score =  128 bits (308), Expect = 1e-27
 Identities = 131/496 (26%), Positives = 202/496 (40%), Gaps = 46/496 (9%)

Query: 12  PYIIEQPLDV---TVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
           P +++QP +    T       +L+CRA G       W K G  +   T+  ++   G   
Sbjct: 23  PILMQQPEETIFDTATNVDSVSLHCRATGDEPITYTWEKDGAPLSQATNARLVITPGQLT 82

Query: 69  LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS-AQGDTVVL 127
           + +    V  D G Y C A+N  G+ RS  A L  A + + F     S QS   G    +
Sbjct: 83  ITSPERTV--DGGEYVCMASNQVGSVRSLPAELVFAYV-DSFDPSATSTQSLTAGQGGCV 139

Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC------I 181
            C PP   P   V W      L+   DSR+ ++D G L    A  +DAG Y+C      I
Sbjct: 140 TCNPPPHFPGILVNWFHENM-LVDSSDSRIRVMDDGRLCFFYALASDAGAYRCQVKSNVI 198

Query: 182 ARNAAGTRESAIATLKIH-------IKPYLITGPEDVVAQTGSSVTFQCRV-GGDP---L 230
           +      R S + T+ ++       I+      P DV    G  V F+C   G  P   +
Sbjct: 199 SDGGVEMRVSPLVTVTVNAGSSSSAIRIVQENRPTDVTTIAGEDVKFECFFYGPQPTGQI 258

Query: 231 PDVLW-RRSAGGGNMPLGRVKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYL 287
           P V W R S  G  +P GR  VL++G   L +  V L D G Y C  ++     SA   L
Sbjct: 259 PRVQWVRTSPPGAGLPTGRA-VLEEGGEILSIVGVQLEDAGSYLCYIDDVNSGASAG--L 315

Query: 288 TVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
            V + P+    P     +   +  +   A    + T  W   G    I     R ++   
Sbjct: 316 NVAEAPAWVSEPMDAMKDINTMQEWNVEAEEADQYT--WYRNGE---ILTARDRHQFR-- 368

Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407
              + +  L I+D    D+     C A N  G  +   +L+V +    PP  ++   +++
Sbjct: 369 ---NNLETLIISDLMTTDTA-MYQCFASNDHGMIYSAAQLSVRAF---PPEFLSPMETDK 421

Query: 408 TLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND-GTLVLKDLDKSDSGTYT 466
             P+ +     C     P P + W  +G+ +    R N+T D   LV+ D+  SD GTY 
Sbjct: 422 PAPLTATVTVVCDVDAAPAPTVTWQHDGQPITDGARYNLTADPPNLVIIDVQMSDGGTYQ 481

Query: 467 CVASSRHGKYVWSGAL 482
           C A++ +G     G+L
Sbjct: 482 CTATNSNGTVTGEGSL 497



 Score =   99 bits (238), Expect = 4e-19
 Identities = 86/327 (26%), Positives = 138/327 (42%), Gaps = 18/327 (5%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLFF 68
           EAP  + +P+D     +     N  A    +    WY+ G +L   D H+       L  
Sbjct: 319 EAPAWVSEPMDAMKDINTMQEWNVEA--EEADQYTWYRNGEILTARDRHQFRNNLETLII 376

Query: 69  LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
                  + +D  +Y C A+N +G   S  A L V     EF    E+ + A     V  
Sbjct: 377 ----SDLMTTDTAMYQCFASNDHGMIYSA-AQLSVRAFPPEFLSPMETDKPAPLTATVTV 431

Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
                 +P P V W+ +GQ +  DG       D  NLVI D + +D G YQC A N+ GT
Sbjct: 432 VCDVDAAPAPTVTWQHDGQPIT-DGARYNLTADPPNLVIIDVQMSDGGTYQCTATNSNGT 490

Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG- 247
             +   +L I     +   P++ + + G S T +C+   D   ++ +     G  + L  
Sbjct: 491 -VTGEGSLDIKDATVITGHPDNTLVEVGQSTTLKCKAAHDEYLELTYLWEHNGVEIDLSE 549

Query: 248 --RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
             R ++ D+G+L + +  L D GEY+C A     +  +S  L +  PP     P+ ++VE
Sbjct: 550 IERYRMRDNGNLEIVSAQLRDGGEYTCVALTVADSDRSSATLDIAGPPG---PPSGLSVE 606

Query: 306 SGNVARFT--CTATGRPEPTMFWSVEG 330
             N+A        T    P   +++EG
Sbjct: 607 VENLAANLRWVPGTDNNSPITSFTIEG 633



 Score = 74.1 bits (174), Expect = 2e-11
 Identities = 90/335 (26%), Positives = 126/335 (37%), Gaps = 22/335 (6%)

Query: 7   TSGEAPYIIEQ--PLDVTVARHQPATLNCRA-GGSPS---PAIRWYKGGVLVVS-DTHRS 59
           +S  A  I+++  P DVT    +     C   G  P+   P ++W +         T R+
Sbjct: 219 SSSSAIRIVQENRPTDVTTIAGEDVKFECFFYGPQPTGQIPRVQWVRTSPPGAGLPTGRA 278

Query: 60  ILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS 119
           +L  GG     +  G    DAG Y C   +    A   +A L+VA     +  EP     
Sbjct: 279 VLEEGGEIL--SIVGVQLEDAGSYLCYIDDVNSGA---SAGLNVAEA-PAWVSEP---MD 329

Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179
           A  D   ++             W +NG+ +L   D      +   L+I D   TD   YQ
Sbjct: 330 AMKDINTMQEWNVEAEEADQYTWYRNGE-ILTARDRHQFRNNLETLIISDLMTTDTAMYQ 388

Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
           C A N  G   SA A L +   P     P   D  A   ++VT  C V   P P V W+ 
Sbjct: 389 CFASNDHGMIYSA-AQLSVRAFPPEFLSPMETDKPAPLTATVTVVCDVDAAPAPTVTWQH 447

Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
                          D  +L + +V ++D G Y C A NS G V+  G L + D   I  
Sbjct: 448 DGQPITDGARYNLTADPPNLVIIDVQMSDGGTYQCTATNSNGTVTGEGSLDIKDATVITG 507

Query: 298 SPNSVNVESGNVARFTCTATGRP--EPTMFWSVEG 330
            P++  VE G      C A      E T  W   G
Sbjct: 508 HPDNTLVEVGQSTTLKCKAAHDEYLELTYLWEHNG 542



 Score = 72.5 bits (170), Expect = 6e-11
 Identities = 106/457 (23%), Positives = 166/457 (36%), Gaps = 52/457 (11%)

Query: 39  PSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN---SYGTA 94
           P   + W+   +LV  SD+   ++  G L F  A    + SDAG Y C+  +   S G  
Sbjct: 148 PGILVNWFHENMLVDSSDSRIRVMDDGRLCFFYA----LASDAGAYRCQVKSNVISDGGV 203

Query: 95  RSR---------NATLHVAVLREEFRLEPESKQSAQGDTVVLECL---PPRGSPEPNVYW 142
             R         NA    + +R      P    +  G+ V  EC    P      P V W
Sbjct: 204 EMRVSPLVTVTVNAGSSSSAIRIVQENRPTDVTTIAGEDVKFECFFYGPQPTGQIPRVQW 263

Query: 143 KKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201
            +           R  L +GG ++ I   +  DAG Y C   +       A A L +   
Sbjct: 264 VRTSPPGAGLPTGRAVLEEGGEILSIVGVQLEDAGSYLCYIDDV---NSGASAGLNVAEA 320

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLR--- 258
           P  ++ P D +    +   +   V  +      W R+   G +   R +     +L    
Sbjct: 321 PAWVSEPMDAMKDINTMQEWN--VEAEEADQYTWYRN---GEILTARDRHQFRNNLETLI 375

Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT--CTA 316
           + +++  D   Y C A N  G + ++  L+V   P   LSP   +  +   A  T  C  
Sbjct: 376 ISDLMTTDTAMYQCFASNDHGMIYSAAQLSVRAFPPEFLSPMETDKPAPLTATVTVVCDV 435

Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
              P PT+ W  +G      P     +Y+ TA    + ++ +  +D      T  C+A N
Sbjct: 436 DAAPAPTVTWQHDGQ-----PITDGARYNLTADPPNLVIIDVQMSDGG----TYQCTATN 486

Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP--EPIIAWYFE 434
             G+    G L     D +   +IT  P N  + +       C A      E    W   
Sbjct: 487 SNGTVTGEGSL-----DIKDATVITGHPDNTLVEVGQSTTLKCKAAHDEYLELTYLWEHN 541

Query: 435 GEA--LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
           G    L +  R  + ++G L +      D G YTCVA
Sbjct: 542 GVEIDLSEIERYRMRDNGNLEIVSAQLRDGGEYTCVA 578



 Score = 36.7 bits (81), Expect = 3.9
 Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 2/123 (1%)

Query: 700 YTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQL 759
           YT+Y   +     + EG  S   V  +  + P   P  ++    + TT+++ W   +   
Sbjct: 766 YTQYNVRVQAKNDEGEGPFSEWAVIYSYQEAPKTAPTGVKAERASGTTINVSWDAIDEST 825

Query: 760 QNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819
             G + GY +   W D  +N++      ++   TS  +  L     Y+V +AA +  G G
Sbjct: 826 FEGELMGYKLKY-WSD-DSNEANANTAVSLGVGTSNTIAGLEPSTRYTVMVAAYSGGGNG 883

Query: 820 PFS 822
           P S
Sbjct: 884 PDS 886


>UniRef50_UPI0000D5796D Cluster: PREDICTED: similar to CG31190-PA,
           isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG31190-PA, isoform A - Tribolium castaneum
          Length = 1613

 Score =  127 bits (307), Expect = 2e-27
 Identities = 134/508 (26%), Positives = 204/508 (40%), Gaps = 49/508 (9%)

Query: 21  VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL--PAGGLFFLRATHGRVHS 78
           V+  R     L C A G+P P   W++     +   H S    P+  +  +R        
Sbjct: 13  VSADRETDIHLTCSAQGNPPPTFNWFREIEGHLQPVHSSARFEPSQDILHIRRLKSE--- 69

Query: 79  DAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPE 137
           DAG + C+ +N++G  R     +H+ V       + P+ +    G++ +  C    GSP 
Sbjct: 70  DAGRWTCKVSNNFGEQR---LDIHLTVTAHLSVHVLPQLQVINSGESAIFNCTVS-GSPV 125

Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
             + W +NG+ LL DG+ ++ L+    L +    + D G YQC+ RN    RESA  + +
Sbjct: 126 GRILWFRNGEPLLTDGNRKVKLLSPLVLAVYGVTRHDRGMYQCVVRN---DRESAQGSAE 182

Query: 198 IHIK---PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA------GGGNMPLGR 248
           + +    P L     +   + G  V+ +C   G P P   W            G+     
Sbjct: 183 LRLGDTIPELQYTFIEQAMRPGPQVSLRCSASGSPPPQFRWLLDGEPLSDISSGHRYAIS 242

Query: 249 VKVLDDGS----LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
             V  +G     L + NV + D G YSC A NS+G+   S  L +Y PP I  S   V  
Sbjct: 243 QYVDQNGDVISHLNISNVRVEDGGLYSCRALNSLGSTEHSARLNIYGPPFIR-SIGPVKA 301

Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
            +G      C  +G P  ++ W   G        +  D  H     +G   LTI+  D  
Sbjct: 302 VAGADITLHCPYSGYPIGSVRWERHGQE------LPLDLRHRLGE-EGS--LTISRLDPA 352

Query: 365 DSRNTIVCSAVNYAGSSFVRG-KLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
                  C   +  G    R  +L V S     PPI+       +L     A   C+   
Sbjct: 353 TDSGFYACFVTSRDGEVARREIQLIVNS-----PPILEPFRFPASLQEGGRAQVTCSVTS 407

Query: 424 TPEPI-IAWYFEGE---ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479
              PI  AWY +GE   A +Q   R       L+ K++    SG+YTCVAS+   +  ++
Sbjct: 408 GDMPIHFAWYKDGEHISAALQVEERAAEFYSILIFKEISSKHSGSYTCVASNSAARANYT 467

Query: 480 GALLVDSPINPNIHFFRAADVSSLPGPP 507
             L+V   + P        DVS L G P
Sbjct: 468 AQLMV--KVTPQ-WVTEPQDVSVLLGNP 492



 Score = 81.4 bits (192), Expect = 1e-13
 Identities = 84/309 (27%), Positives = 123/309 (39%), Gaps = 19/309 (6%)

Query: 30  TLNCRAGGSPSPAIRWYKGGVLV--VSDTHR----SILPAGG--LFFLRATHGRVHSDAG 81
           +L C A GSP P  RW   G  +  +S  HR      +   G  +  L  ++ RV  D G
Sbjct: 208 SLRCSASGSPPPQFRWLLDGEPLSDISSGHRYAISQYVDQNGDVISHLNISNVRVE-DGG 266

Query: 82  VYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVY 141
           +Y C A NS G+    +A L++      F       ++  G  + L C P  G P  +V 
Sbjct: 267 LYSCRALNSLGSTE-HSARLNI--YGPPFIRSIGPVKAVAGADITLHC-PYSGYPIGSVR 322

Query: 142 WKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ-TDAGRYQCIARNAAGTRESAIATLKIHI 200
           W+++GQ L  D   R  L + G+L I      TD+G Y C   +  G        L ++ 
Sbjct: 323 WERHGQELPLD--LRHRLGEEGSLTISRLDPATDSGFYACFVTSRDGEVARREIQLIVNS 380

Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRRSAGGGNMPLG-RVKVLDDGSLR 258
            P L         Q G      C V    +P    W +     +  L    +  +  S+ 
Sbjct: 381 PPILEPFRFPASLQEGGRAQVTCSVTSGDMPIHFAWYKDGEHISAALQVEERAAEFYSIL 440

Query: 259 LDNVILADE-GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
           +   I +   G Y+C A NS    + +  L V   P     P  V+V  GN     C+A 
Sbjct: 441 IFKEISSKHSGSYTCVASNSAARANYTAQLMVKVTPQWVTEPQDVSVLLGNPVLVGCSAK 500

Query: 318 GRPEPTMFW 326
           G PEP + W
Sbjct: 501 GFPEPQITW 509



 Score = 70.9 bits (166), Expect = 2e-10
 Identities = 56/214 (26%), Positives = 89/214 (41%), Gaps = 10/214 (4%)

Query: 30  TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
           TL+C   G P  ++RW + G  +  D    +   G L   R       +D+G Y C  T+
Sbjct: 308 TLHCPYSGYPIGSVRWERHGQELPLDLRHRLGEEGSLTISRLDPA---TDSGFYACFVTS 364

Query: 90  SYGTARSRNATLHV--AVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
             G    R   L V    + E FR  P S Q  +G    + C    G    +  W K+G+
Sbjct: 365 RDGEVARREIQLIVNSPPILEPFRF-PASLQ--EGGRAQVTCSVTSGDMPIHFAWYKDGE 421

Query: 148 TLLFDGDSRMHLVDGGNLVI-QDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT 206
            +           +  +++I ++     +G Y C+A N+A  R +  A L + + P  +T
Sbjct: 422 HISAALQVEERAAEFYSILIFKEISSKHSGSYTCVASNSAA-RANYTAQLMVKVTPQWVT 480

Query: 207 GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
            P+DV    G+ V   C   G P P + W +  G
Sbjct: 481 EPQDVSVLLGNPVLVGCSAKGFPEPQITWLKGQG 514



 Score = 62.9 bits (146), Expect = 5e-08
 Identities = 40/138 (28%), Positives = 65/138 (47%), Gaps = 8/138 (5%)

Query: 693 EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKW 752
           ++T LRK+T+Y+  +  F     G  S + +  T + VP+ PP NI    +++ ++ + W
Sbjct: 767 QLTGLRKFTRYDINVRAFNSISTGPASPTVIGTTKEGVPEAPPQNIACSQISSQSMKISW 826

Query: 753 SPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH----QATSLIMTNLTSGVSYSV 808
           +PP   L  G+I GY V       P     V I TT       +T   +  L    +YS+
Sbjct: 827 TPPPQTLHGGLIQGYKVYYR----PLPNENVDIPTTGEVKRTSSTETYLHTLFKYTNYSI 882

Query: 809 QIAAETIIGLGPFSQKVY 826
           ++ A T  G G  S  +Y
Sbjct: 883 KVLAYTGAGDGLMSTPLY 900



 Score = 54.0 bits (124), Expect = 2e-05
 Identities = 54/222 (24%), Positives = 83/222 (37%), Gaps = 29/222 (13%)

Query: 387  LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNV 446
            +   + + R P  I +       PIKS  + PC A+  P P   W    + +  +    +
Sbjct: 1001 IVAQATNSRAPSRIASFSQTIKKPIKSKILLPCLAVGNPTPRTRWIHREKPITFSSFYEI 1060

Query: 447  TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGP 506
            T++G L +   D+S SG YTC A +  G    +  L+V  P                P  
Sbjct: 1061 TSEGHLNIHSADQSLSGNYTCSAKNLFGDDNITYTLMVLMP----------------PSA 1104

Query: 507  PTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARR 566
            P   +  + T  S+ L W+Q    G S I GY +           NT   +  W  +   
Sbjct: 1105 PILEVQFS-TSRSIRLHWTQPED-GGSIIQGYTL-----------NTKHETDDWTSLELS 1151

Query: 567  VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVG 608
               + Y + +L  G  Y   +   N  G   PSP+    T G
Sbjct: 1152 PEHSVYNLDNLRCGSIYHIYLLAHNRVGNGSPSPILTVNTKG 1193



 Score = 52.8 bits (121), Expect = 5e-05
 Identities = 35/135 (25%), Positives = 64/135 (47%), Gaps = 7/135 (5%)

Query: 639 IEATPIDSKTIKLMW----EILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEI 694
           I  + I S+++K+ W    + L+   ++G  +Y+RPL N  ++      +     +   +
Sbjct: 812 IACSQISSQSMKISWTPPPQTLHGGLIQGYKVYYRPLPNENVDIPTTGEVKRTSSTETYL 871

Query: 695 TSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSP 754
            +L KYT Y   ++ +    +G  S      T +D+P GPP +I+   L   ++ + W P
Sbjct: 872 HTLFKYTNYSIKVLAYTGAGDGLMSTPLYCVTEEDLP-GPPADIKAAALTGESILVSWLP 930

Query: 755 PELQLQNGIITGYNV 769
           P     NG I+ Y V
Sbjct: 931 P--SKPNGRISHYTV 943



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 31/122 (25%), Positives = 49/122 (40%), Gaps = 6/122 (4%)

Query: 83   YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG--DTVVLECLPPRGSPEPNV 140
            +W  AT S G              R   R+   S+   +     ++L CL   G+P P  
Sbjct: 985  FWISATTSIGEGEPTAIVAQATNSRAPSRIASFSQTIKKPIKSKILLPCLAV-GNPTPRT 1043

Query: 141  YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
             W    + + F   S   +   G+L I  A Q+ +G Y C A+N  G  ++   TL + +
Sbjct: 1044 RWIHREKPITFS--SFYEITSEGHLNIHSADQSLSGNYTCSAKNLFGD-DNITYTLMVLM 1100

Query: 201  KP 202
             P
Sbjct: 1101 PP 1102



 Score = 36.3 bits (80), Expect = 5.1
 Identities = 15/37 (40%), Positives = 19/37 (51%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG 48
           P  + +P DV+V    P  + C A G P P I W KG
Sbjct: 476 PQWVTEPQDVSVLLGNPVLVGCSAKGFPEPQITWLKG 512



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 25/104 (24%), Positives = 45/104 (43%), Gaps = 3/104 (2%)

Query: 723 VAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSM 782
           + +T ++ P   P ++ +  +    + L W+ P  +  NG + GY  +V+W +     + 
Sbjct: 695 IVKTQEEEPSEAPKDVRVESVGPGELFLTWAVPARESWNGELLGY--IVSWNEHGGLPNQ 752

Query: 783 VAINTTVHQATS-LIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
               T    AT+ L +T L     Y + + A   I  GP S  V
Sbjct: 753 TKSLTVKGWATTKLQLTGLRKFTRYDINVRAFNSISTGPASPTV 796


>UniRef50_Q4SIF9 Cluster: Chromosome 5 SCAF14581, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 5 SCAF14581, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 676

 Score =  126 bits (304), Expect = 4e-27
 Identities = 98/343 (28%), Positives = 142/343 (41%), Gaps = 31/343 (9%)

Query: 18  PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
           P  VTV R +   L+C A G     +RW K G  V  +    +L  G L+       R  
Sbjct: 1   PRHVTVTRREAVVLDCHARGEAPVDVRWLKNGARVAQNQRVYLLANGSLYISEVESRRGD 60

Query: 78  -SDAGVYWCEATNSYGTARSRNATLHVAVLREE-----------------FRLEPESKQS 119
            SD G+Y C A N +G   S+ A L +A L                    F ++P S   
Sbjct: 61  KSDEGLYQCLAQNRHGAILSQKARLTIATLCRSAPCFKRGVEKLWARISPFTIQPASLVV 120

Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179
            QG      C      P P + W+ N   L    + RM ++  G L I   ++TDAG Y+
Sbjct: 121 TQGSVARFSC-KITAHPPPIITWEFNRVPLPLITE-RMTVLPSGVLQIYGVQRTDAGSYR 178

Query: 180 CIARNAAGTRESAIATLKIHI--------KPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231
           C A N    R SA   L +          +P +I GP+++      +   +C   G+P P
Sbjct: 179 CTATNIGSRRRSAEGFLTVTPAPNPPLPQRPRIIAGPQNISVSLHHNAILECMATGNPRP 238

Query: 232 DVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAEN--SVGAVSASGYLTV 289
            + W R A   ++ +   KVL +G+L + +V     G Y C A    +     A+  +TV
Sbjct: 239 IISWSR-ADSKSIDVYNTKVLGNGNLIITDVKPQHGGVYVCRATTPGTRNYTVAAANITV 297

Query: 290 YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332
             PPS+   P S+       ARF C A G P P + W   G +
Sbjct: 298 LAPPSLVEWPESLTRPRAGTARFVCQAEGVPAPQITWLKNGEK 340



 Score =  101 bits (242), Expect = 1e-19
 Identities = 100/355 (28%), Positives = 147/355 (41%), Gaps = 52/355 (14%)

Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR-----QTDAGR 177
           + VVL+C   RG    +V W KNG  +    + R++L+  G+L I +       ++D G 
Sbjct: 10  EAVVLDC-HARGEAPVDVRWLKNGARVA--QNQRVYLLANGSLYISEVESRRGDKSDEGL 66

Query: 178 YQCIARNAAGTRESAIATLKI-------------------HIKPYLITGPEDVVAQTGSS 218
           YQC+A+N  G   S  A L I                    I P+ I  P  +V   GS 
Sbjct: 67  YQCLAQNRHGAILSQKARLTIATLCRSAPCFKRGVEKLWARISPFTIQ-PASLVVTQGSV 125

Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSV 278
             F C++   P P + W  +     +   R+ VL  G L++  V   D G Y C A N +
Sbjct: 126 ARFSCKITAHPPPIITWEFNRVPLPLITERMTVLPSGVLQIYGVQRTDAGSYRCTATN-I 184

Query: 279 GAV--SASGYLTVYDPPS--------INLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328
           G+   SA G+LTV   P+        I   P +++V   + A   C ATG P P + WS 
Sbjct: 185 GSRRRSAEGFLTVTPAPNPPLPQRPRIIAGPQNISVSLHHNAILECMATGNPRPIISWSR 244

Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT 388
             +++I       D Y+   + +G  ++T  D  K       VC A      ++      
Sbjct: 245 ADSKSI-------DVYNTKVLGNGNLIIT--DV-KPQHGGVYVCRATTPGTRNYTVAAAN 294

Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR 443
           +T      PP +   P + T P    A F C A   P P I W   GE +  N R
Sbjct: 295 ITV---LAPPSLVEWPESLTRPRAGTARFVCQAEGVPAPQITWLKNGEKVHSNGR 346



 Score = 84.6 bits (200), Expect = 1e-14
 Identities = 69/253 (27%), Positives = 108/253 (42%), Gaps = 20/253 (7%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFFL 69
           +P+ I QP  + V +   A  +C+    P P I W    V +   T R ++LP+G L   
Sbjct: 109 SPFTI-QPASLVVTQGSVARFSCKITAHPPPIITWEFNRVPLPLITERMTVLPSGVL--- 164

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVL-------REEFRLEPESKQSAQG 122
              +G   +DAG Y C ATN     RS    L V          R      P++   +  
Sbjct: 165 -QIYGVQRTDAGSYRCTATNIGSRRRSAEGFLTVTPAPNPPLPQRPRIIAGPQNISVSLH 223

Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
              +LEC+   G+P P + W +     +   +++  ++  GNL+I D +    G Y C A
Sbjct: 224 HNAILECM-ATGNPRPIISWSRADSKSIDVYNTK--VLGNGNLIITDVKPQHGGVYVCRA 280

Query: 183 RNAAGTRESAIATLKIHI--KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
               GTR   +A   I +   P L+  PE +      +  F C+  G P P + W ++ G
Sbjct: 281 -TTPGTRNYTVAAANITVLAPPSLVEWPESLTRPRAGTARFVCQAEGVPAPQITWLKN-G 338

Query: 241 GGNMPLGRVKVLD 253
                 GR+K+ D
Sbjct: 339 EKVHSNGRIKMYD 351



 Score = 82.2 bits (194), Expect = 8e-14
 Identities = 83/292 (28%), Positives = 120/292 (41%), Gaps = 38/292 (13%)

Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL--- 264
           P  V      +V   C   G+   DV W ++ G       RV +L +GSL +  V     
Sbjct: 1   PRHVTVTRREAVVLDCHARGEAPVDVRWLKN-GARVAQNQRVYLLANGSLYISEVESRRG 59

Query: 265 --ADEGEYSCEAENSVGAV-SASGYLTVY----DPPSIN--------------LSPNSVN 303
             +DEG Y C A+N  GA+ S    LT+       P                 + P S+ 
Sbjct: 60  DKSDEGLYQCLAQNRHGAILSQKARLTIATLCRSAPCFKRGVEKLWARISPFTIQPASLV 119

Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
           V  G+VARF+C  T  P P + W  E NR +  P ++      T +  GV  L I    +
Sbjct: 120 VTQGSVARFSCKITAHPPPIITW--EFNR-VPLPLITE---RMTVLPSGV--LQIYGVQR 171

Query: 364 NDSRNTIVCSAVNYAGSS-FVRGKLTVTSDDDRP---PPIITNGPSNQTLPIKSMAVFPC 419
            D+  +  C+A N         G LTVT   + P    P I  GP N ++ +   A+  C
Sbjct: 172 TDA-GSYRCTATNIGSRRRSAEGFLTVTPAPNPPLPQRPRIIAGPQNISVSLHHNAILEC 230

Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
            A   P PII+W       I  +   V  +G L++ D+     G Y C A++
Sbjct: 231 MATGNPRPIISWSRADSKSIDVYNTKVLGNGNLIITDVKPQHGGVYVCRATT 282



 Score = 65.3 bits (152), Expect = 1e-08
 Identities = 46/152 (30%), Positives = 68/152 (44%), Gaps = 11/152 (7%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF- 68
           + P II  P +++V+ H  A L C A G+P P I W +     +   +  +L  G L   
Sbjct: 207 QRPRIIAGPQNISVSLHHNAILECMATGNPRPIISWSRADSKSIDVYNTKVLGNGNLIIT 266

Query: 69  -LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVV 126
            ++  HG      GVY C AT   GT     A  ++ VL     +E PES    +  T  
Sbjct: 267 DVKPQHG------GVYVCRATTP-GTRNYTVAAANITVLAPPSLVEWPESLTRPRAGTAR 319

Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH 158
             C    G P P + W KNG+ +  +G  +M+
Sbjct: 320 FVC-QAEGVPAPQITWLKNGEKVHSNGRIKMY 350



 Score = 50.0 bits (114), Expect = 4e-04
 Identities = 45/206 (21%), Positives = 87/206 (42%), Gaps = 9/206 (4%)

Query: 639 IEATPIDSKTIKLMWE--ILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITS 696
           ++A  + S  I L WE  + N   +    +++   + +  E E + ++  ND + + I  
Sbjct: 433 VQADTVSSSAILLAWERPLYNSDKVIAYSVHYMKAEGLNNE-EYQVVI-GNDTTRYIIDD 490

Query: 697 LRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPE 756
           L     Y F+++ +      + S+     T +DVP   P  + +   + T + + W P  
Sbjct: 491 LEPARNYTFYIVAYMALGASRMSDHVFQCTFEDVPLRAP-ELSLTSHSPTDIQVSWQPLP 549

Query: 757 LQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETII 816
            +L  G ++ Y++     D  A  S V ++    + T  ++ NL    +Y ++IAA T +
Sbjct: 550 EKLSRGRVSAYSLSYRSGDGGA-VSQVELS---GEQTQHLLENLQPDTTYLLRIAAATSV 605

Query: 817 GLGPFSQKVYFNIDSRSVGLDLLSRY 842
           G G  S          S   D   +Y
Sbjct: 606 GWGEQSVWTSHRTPKASTARDPRKKY 631



 Score = 41.5 bits (93), Expect = 0.14
 Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 5/76 (6%)

Query: 404 PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL-----D 458
           P + T+  +   V  C A       + W   G  + QN R  +  +G+L + ++     D
Sbjct: 1   PRHVTVTRREAVVLDCHARGEAPVDVRWLKNGARVAQNQRVYLLANGSLYISEVESRRGD 60

Query: 459 KSDSGTYTCVASSRHG 474
           KSD G Y C+A +RHG
Sbjct: 61  KSDEGLYQCLAQNRHG 76


>UniRef50_Q8TDY8 Cluster: Neighbor of punc e11 precursor; n=23;
           Theria|Rep: Neighbor of punc e11 precursor - Homo
           sapiens (Human)
          Length = 1250

 Score =  126 bits (304), Expect = 4e-27
 Identities = 102/338 (30%), Positives = 151/338 (44%), Gaps = 32/338 (9%)

Query: 18  PLDVTVARHQPATLNCRAGGS---PSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR--AT 72
           PL V +   Q A LNC  G +   P   + W K G  ++   H  +LP G L+  +  A 
Sbjct: 42  PLQVILGPEQAAVLNCSLGAAAAGPPTRVTWSKDGDTLLEHDHLHLLPNGSLWLSQPLAP 101

Query: 73  HGRVHS--DA-----GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
           +G   S  +A     G Y C A    G   S+ A + +A L + F L PES+   +  T 
Sbjct: 102 NGSDESVPEAVGVIEGNYSCLAHGPLGVLASQTAVVKLATLAD-FSLHPESQTVEENGTA 160

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
             EC    G P P + W+K+  TL    + R+ ++  G L I D +++DAG Y+C+A N+
Sbjct: 161 RFEC-HIEGLPAPIITWEKDQVTL--PEEPRLIVLPNGVLQILDVQESDAGPYRCVATNS 217

Query: 186 AGTRESAIATLKIHIKPYL----------ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
           A    S  A L +  +  L          +  PE+    +G SV  +C    DP P V W
Sbjct: 218 ARQHFSQEALLSVAHRGSLASTRGQDVVIVAAPENTTVVSGQSVVMECVASADPTPFVSW 277

Query: 236 RRSAGGGNMPLGR-VKVLDDGSLRLDNVILADEGEYSCEAEN--SVGAVSASGYLTVYDP 292
            R  G    P+   V VL   +L + N      G Y C A    +    +A+  L V   
Sbjct: 278 VRQDG---KPISTDVIVLGRTNLLIANAQPWHSGVYVCRANKPRTRDFATAAAELRVLAA 334

Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
           P+I  +P +++    + ARF C A+G P P + W   G
Sbjct: 335 PAITQAPEALSRTRASTARFVCRASGEPRPALRWLHNG 372



 Score =  112 bits (269), Expect = 6e-23
 Identities = 95/298 (31%), Positives = 135/298 (45%), Gaps = 24/298 (8%)

Query: 18  PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
           P   TV  +  A   C   G P+P I W K  V +  +    +LP G L  L        
Sbjct: 149 PESQTVEENGTARFECHIEGLPAPIITWEKDQVTLPEEPRLIVLPNGVLQILDVQE---- 204

Query: 78  SDAGVYWCEATNSYGTARSRNATLHVA-------VLREEFRL--EPESKQSAQGDTVVLE 128
           SDAG Y C ATNS     S+ A L VA          ++  +   PE+     G +VV+E
Sbjct: 205 SDAGPYRCVATNSARQHFSQEALLSVAHRGSLASTRGQDVVIVAAPENTTVVSGQSVVME 264

Query: 129 CLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
           C+     P P V W +++G+ +  D    + ++   NL+I +A+   +G Y C A N   
Sbjct: 265 CVAS-ADPTPFVSWVRQDGKPISTD----VIVLGRTNLLIANAQPWHSGVYVCRA-NKPR 318

Query: 188 TRE--SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
           TR+  +A A L++   P +   PE +     S+  F CR  G+P P + W  + G    P
Sbjct: 319 TRDFATAAAELRVLAAPAITQAPEALSRTRASTARFVCRASGEPRPALRWLHN-GAPLRP 377

Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
            GRVKV   G SL +  + L D G Y C AENS G   A+  L V     +  +P  V
Sbjct: 378 NGRVKVQGGGGSLVITQIGLQDAGYYQCVAENSAGMACAAASLAVVVREGLPSAPTRV 435



 Score = 86.6 bits (205), Expect = 4e-15
 Identities = 108/431 (25%), Positives = 162/431 (37%), Gaps = 58/431 (13%)

Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ--------DARQTDA-----GRYQCIA 182
           P   V W K+G TLL      +HL+  G+L +         D    +A     G Y C+A
Sbjct: 66  PPTRVTWSKDGDTLL--EHDHLHLLPNGSLWLSQPLAPNGSDESVPEAVGVIEGNYSCLA 123

Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
               G   S  A +K+         PE    +   +  F+C + G P P + W +     
Sbjct: 124 HGPLGVLASQTAVVKLATLADFSLHPESQTVEENGTARFECHIEGLPAPIITWEKDQ--V 181

Query: 243 NMP-LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPS------ 294
            +P   R+ VL +G L++ +V  +D G Y C A NS     S    L+V    S      
Sbjct: 182 TLPEEPRLIVLPNGVLQILDVQESDAGPYRCVATNSARQHFSQEALLSVAHRGSLASTRG 241

Query: 295 ----INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
               I  +P +  V SG      C A+  P P + W  +  + I     S D      + 
Sbjct: 242 QDVVIVAAPENTTVVSGQSVVMECVASADPTPFVSWVRQDGKPI-----STD-----VIV 291

Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
            G T L I +     S    VC A       F      +        P IT  P   +  
Sbjct: 292 LGRTNLLIANAQPWHS-GVYVCRANKPRTRDFATAAAELRV---LAAPAITQAPEALSRT 347

Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT-NDGTLVLKDLDKSDSGTYTCVA 469
             S A F C A   P P + W   G  L  N R  V    G+LV+  +   D+G Y CVA
Sbjct: 348 RASTARFVCRASGEPRPALRWLHNGAPLRPNGRVKVQGGGGSLVITQIGLQDAGYYQCVA 407

Query: 470 SSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
            +  G    + +L V                  LP  PT+     ++ ++V ++W +  +
Sbjct: 408 ENSAGMACAAASLAV-------------VVREGLPSAPTRVTATPLSSSAVLVAW-ERPE 453

Query: 530 IGSSSILGYQV 540
           + S  I+G+ +
Sbjct: 454 MHSEQIIGFSL 464



 Score = 73.7 bits (173), Expect = 3e-11
 Identities = 64/213 (30%), Positives = 90/213 (42%), Gaps = 10/213 (4%)

Query: 7   TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66
           T G+   I+  P + TV   Q   + C A   P+P + W +     +S     ++  G  
Sbjct: 239 TRGQDVVIVAAPENTTVVSGQSVVMECVASADPTPFVSWVRQDGKPIST---DVIVLGRT 295

Query: 67  FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTV 125
             L A     HS  GVY C A N   T     A   + VL      + PE+    +  T 
Sbjct: 296 NLLIANAQPWHS--GVYVCRA-NKPRTRDFATAAAELRVLAAPAITQAPEALSRTRASTA 352

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
              C    G P P + W  NG  L  +G  ++    GG+LVI      DAG YQC+A N+
Sbjct: 353 RFVCRAS-GEPRPALRWLHNGAPLRPNGRVKVQ-GGGGSLVITQIGLQDAGYYQCVAENS 410

Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSS 218
           AG    A A+L + ++  L + P  V A   SS
Sbjct: 411 AG-MACAAASLAVVVREGLPSAPTRVTATPLSS 442



 Score = 67.3 bits (157), Expect = 2e-09
 Identities = 50/199 (25%), Positives = 89/199 (44%), Gaps = 17/199 (8%)

Query: 639 IEATPIDSKTIKLMWEILNFY--YLEGLFIYF---RPLDNITIEYEMKTILHSNDVSGFE 693
           + ATP+ S  + + WE    +   + G  +++   R +DN+  EY+      +ND +  +
Sbjct: 435 VTATPLSSSAVLVAWERPEMHSEQIIGFSLHYQKARGMDNV--EYQFAV---NNDTTELQ 489

Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
           +  L   T YEF+++ + +    + S   +  TLDDVP   P  + +   N + + + W 
Sbjct: 490 VRDLEPNTDYEFYVVAYSQLGASRTSTPALVHTLDDVPSAAP-QLSLSSPNPSDIRVAWL 548

Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH-QATSLIMTNLTSGVSYSVQIAA 812
           P    L NG +  Y +     +    K     +T V    T L++ +L     Y V+I+A
Sbjct: 549 PLPPSLSNGQVVKYKI-----EYGLGKEDQIFSTEVRGNETQLMLNSLQPNKVYRVRISA 603

Query: 813 ETIIGLGPFSQKVYFNIDS 831
            T  G G  SQ ++    S
Sbjct: 604 GTAAGFGAPSQWMHHRTPS 622



 Score = 52.0 bits (119), Expect = 1e-04
 Identities = 38/130 (29%), Positives = 56/130 (43%), Gaps = 3/130 (2%)

Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
           I  L+ +TKYEF +       +G   +     TL D P  PP ++ +  L  +TV L W 
Sbjct: 810 IGGLKPFTKYEFAVQSHGVDMDGPFGSVVERSTLPDRPSTPPSDLRLSPLTPSTVRLHWC 869

Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAE 813
           PP     NG I  Y ++ +            + TT     S  +  L S   Y  ++ A 
Sbjct: 870 PP--TEPNGEIVEYLILYSSNHTQPEHQWTLL-TTQGNIFSAEVHGLESDTRYFFKMGAR 926

Query: 814 TIIGLGPFSQ 823
           T +G GPFS+
Sbjct: 927 TEVGPGPFSR 936


>UniRef50_UPI00015B613E Cluster: PREDICTED: similar to frazzled
           protein; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to frazzled protein - Nasonia vitripennis
          Length = 1478

 Score =  125 bits (302), Expect = 6e-27
 Identities = 87/298 (29%), Positives = 141/298 (47%), Gaps = 18/298 (6%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFLR 70
           P    +P D  V   Q A L+C+   S    I+W K    L++ ++  +ILP+G L    
Sbjct: 133 PGFDREPQDTMVYPGQIAYLSCKLATSDQVNIQWLKDEQPLLLDESRMTILPSGALEIDE 192

Query: 71  ATHGRVHSDAGVYWCEATN--SYGTARSRNATLHVAVLREE-----FRLEPESKQSAQGD 123
              G    D G Y C A+    Y  +      L  + + E      F  +P ++ + +  
Sbjct: 193 VLPG----DVGSYRCNASGFGQYRLSTKAQLALQTSDIGEGESMPVFVAKPFNQVAIEKS 248

Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
           T+ LEC    G+P+P VYW K+G ++ L   DSR   V   +L+I+D  + D G YQC A
Sbjct: 249 TITLECAA-NGNPKPEVYWLKDGTSIDLASLDSRYQTVAASSLMIKDVTEEDNGSYQCRA 307

Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
           +N   T + A+A + + + P  I  P+D  A     + F+C + G P P + W ++  G 
Sbjct: 308 KNDIDTLD-AVAEVVVQVPPRFIKRPQDKEASEHQELEFECEIYGKPPPLITWLKN--GE 364

Query: 243 NMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
            + L     L +G +L+++ ++  D G + C   N  G+V AS  LT++ P      P
Sbjct: 365 VIKLSNYWQLTNGYNLKINGLLNIDAGIFQCMGTNPAGSVQASARLTIHQPKKERKGP 422



 Score =  109 bits (262), Expect = 5e-22
 Identities = 92/336 (27%), Positives = 137/336 (40%), Gaps = 29/336 (8%)

Query: 17  QPLDVTVARHQPATLNCRA------GG--SPSPAIRWY-KGG--VLVVSDTHRSILPAGG 65
           +P D+ +   + A L+C A      GG     P I W  + G  +  + D +RS L  G 
Sbjct: 35  EPEDLVLELGKSARLDCEAKIEATPGGLLQDLPVITWRTEDGQPINFIGDKYRSQLENGS 94

Query: 66  LFFLRATHGRVHSDAGVYWCEAT-NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
           L+   A    +    G Y C A+  + G   SR A + +A L   F  EP+      G  
Sbjct: 95  LYISAANQESI----GSYQCVASIENVGAIASRTAVVKLASL-PGFDREPQDTMVYPGQI 149

Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
             L C     S + N+ W K+ Q LL D +SRM ++  G L I +    D G Y+C A  
Sbjct: 150 AYLSCKLAT-SDQVNIQWLKDEQPLLLD-ESRMTILPSGALEIDEVLPGDVGSYRCNASG 207

Query: 185 AAGTRESAIATLKIHIK--------PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
               R S  A L +           P  +  P + VA   S++T +C   G+P P+V W 
Sbjct: 208 FGQYRLSTKAQLALQTSDIGEGESMPVFVAKPFNQVAIEKSTITLECAANGNPKPEVYWL 267

Query: 237 RSAGGGNMPL--GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
           +     ++     R + +   SL + +V   D G Y C A+N +  + A   + V  PP 
Sbjct: 268 KDGTSIDLASLDSRYQTVAASSLMIKDVTEEDNGSYQCRAKNDIDTLDAVAEVVVQVPPR 327

Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
               P            F C   G+P P + W   G
Sbjct: 328 FIKRPQDKEASEHQELEFECEIYGKPPPLITWLKNG 363



 Score =  103 bits (246), Expect = 4e-20
 Identities = 95/398 (23%), Positives = 154/398 (38%), Gaps = 32/398 (8%)

Query: 109 EFRLEPESKQSAQGDTVVLEC-----LPPRGSPE--PNVYWK-KNGQTLLFDGDSRMHLV 160
           +F  EPE      G +  L+C       P G  +  P + W+ ++GQ + F GD     +
Sbjct: 31  QFSHEPEDLVLELGKSARLDCEAKIEATPGGLLQDLPVITWRTEDGQPINFIGDKYRSQL 90

Query: 161 DGGNLVIQDARQTDAGRYQCIAR-NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSV 219
           + G+L I  A Q   G YQC+A     G   S  A +K+   P     P+D +   G   
Sbjct: 91  ENGSLYISAANQESIGSYQCVASIENVGAIASRTAVVKLASLPGFDREPQDTMVYPGQIA 150

Query: 220 TFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAEN-SV 278
              C++      ++ W +      +   R+ +L  G+L +D V+  D G Y C A     
Sbjct: 151 YLSCKLATSDQVNIQWLKDEQPLLLDESRMTILPSGALEIDEVLPGDVGSYRCNASGFGQ 210

Query: 279 GAVSASGYLTVYDP--------PSINLSP-NSVNVESGNVARFTCTATGRPEPTMFWSVE 329
             +S    L +           P     P N V +E   +    C A G P+P ++W  +
Sbjct: 211 YRLSTKAQLALQTSDIGEGESMPVFVAKPFNQVAIEKSTIT-LECAANGNPKPEVYWLKD 269

Query: 330 GNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389
           G  T I       +Y   A     + L I D  + D+  +  C A N   +     ++ V
Sbjct: 270 G--TSIDLASLDSRYQTVAA----SSLMIKDVTEEDN-GSYQCRAKNDIDTLDAVAEVVV 322

Query: 390 TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND 449
                + PP     P ++         F C     P P+I W   GE +  ++   +TN 
Sbjct: 323 -----QVPPRFIKRPQDKEASEHQELEFECEIYGKPPPLITWLKNGEVIKLSNYWQLTNG 377

Query: 450 GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
             L +  L   D+G + C+ ++  G    S  L +  P
Sbjct: 378 YNLKINGLLNIDAGIFQCMGTNPAGSVQASARLTIHQP 415



 Score = 79.0 bits (186), Expect = 7e-13
 Identities = 59/199 (29%), Positives = 85/199 (42%), Gaps = 16/199 (8%)

Query: 6   VTSGEA-PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSDTHRSIL 61
           +  GE+ P  + +P +         TL C A G+P P + W K G    L   D+    +
Sbjct: 226 IGEGESMPVFVAKPFNQVAIEKSTITLECAANGNPKPEVYWLKDGTSIDLASLDSRYQTV 285

Query: 62  PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV-LREEFRLEPESKQSA 120
            A  L     T      D G Y C A N   T    +A   V V +   F   P+ K+++
Sbjct: 286 AASSLMIKDVT----EEDNGSYQCRAKNDIDTL---DAVAEVVVQVPPRFIKRPQDKEAS 338

Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
           +   +  EC    G P P + W KNG+ +     +   L +G NL I      DAG +QC
Sbjct: 339 EHQELEFEC-EIYGKPPPLITWLKNGEVIKL--SNYWQLTNGYNLKINGLLNIDAGIFQC 395

Query: 181 IARNAAGTRESAIATLKIH 199
           +  N AG+ + A A L IH
Sbjct: 396 MGTNPAGSVQ-ASARLTIH 413



 Score = 70.1 bits (164), Expect = 3e-10
 Identities = 63/237 (26%), Positives = 103/237 (43%), Gaps = 17/237 (7%)

Query: 588 RTENSHGLSGPSPVSDSV--TVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPID 645
           R E +  +SG  P +  +   V + SN L   + V   T      +  H + L    P  
Sbjct: 580 REETTVTISGLQPGTTYLFRAVANVSNVLSASSKVLELTTESEPNVPSHPLNL-RGWPTS 638

Query: 646 SKTIKLMWE--ILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKY 703
           S++I L WE        + G  I +   D     YE      +N  + +E+T L+ Y +Y
Sbjct: 639 SQSIMLSWEEPTTTNGRISGYLITYAEGD-----YEELNRNTTN--TSYELTGLKPYREY 691

Query: 704 EFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGI 763
             ++        G  ++    +T  DVP  PP N+ +     T++ ++W PP  + QNGI
Sbjct: 692 NIWVQAINDNGPGASTSEIRVRTFGDVPSNPP-NVTIEAGGATSIVIRWEPPS-EGQNGI 749

Query: 764 ITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGP 820
           ITGY +     D   + S++   TT   A   ++  L   +SY V++ A  + G GP
Sbjct: 750 ITGYKIRYRPTDRRIHSSLI---TTDGNARYYVLNRLQKNISYQVRVCAFNVNGTGP 803



 Score = 49.6 bits (113), Expect = 5e-04
 Identities = 32/114 (28%), Positives = 52/114 (45%), Gaps = 6/114 (5%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P  I++P D   + HQ     C   G P P I W K G ++    +  +     L     
Sbjct: 326 PRFIKRPQDKEASEHQELEFECEIYGKPPPLITWLKNGEVIKLSNYWQLTNGYNL----K 381

Query: 72  THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
            +G ++ DAG++ C  TN  G+ ++ +A L +   ++E R  P   +SA G  V
Sbjct: 382 INGLLNIDAGIFQCMGTNPAGSVQA-SARLTIHQPKKE-RKGPGRHRSANGKPV 433



 Score = 43.2 bits (97), Expect = 0.044
 Identities = 39/145 (26%), Positives = 65/145 (44%), Gaps = 7/145 (4%)

Query: 694  ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNT--TTVHLK 751
            I  L+  T+YEF +     + E   S   + +TL+  P  PP ++ +  ++    +V L+
Sbjct: 986  IHDLKPNTEYEFTVKVVKGRRESPWSMVVMNKTLEAKPSSPPRDLTVQSIDEYPKSVLLR 1045

Query: 752  WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIM-TNLTSGVSYSVQI 810
            W PP+L   NG I GY ++    D   ++        V   T  ++   L    +Y  +I
Sbjct: 1046 WLPPKLS--NGDINGY-IIRYTTDNNKDERDWKTEAFVGDKTEFVLPAELQPSTTYYFKI 1102

Query: 811  AAETIIGLGPFSQKV-YFNIDSRSV 834
             A    G GPFS  V Y  + S+ +
Sbjct: 1103 GARNAKGYGPFSSTVPYRTLKSKHI 1127


>UniRef50_Q9VN14 Cluster: Contactin precursor; n=4;
           Endopterygota|Rep: Contactin precursor - Drosophila
           melanogaster (Fruit fly)
          Length = 1390

 Score =  125 bits (302), Expect = 6e-27
 Identities = 116/489 (23%), Positives = 193/489 (39%), Gaps = 42/489 (8%)

Query: 12  PYIIEQPLDVT--VARHQ---PATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP-AGG 65
           PY ++QP D T  V +++     TL+C A G P+P+  WY+   +     ++ I P A  
Sbjct: 362 PYFVKQPNDTTFDVNKNRLINDVTLSCLANGYPTPSYTWYREVYVDDRLEYQKIDPLAQD 421

Query: 66  LFFLRATHGRVHS-----DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA 120
            + +   +  ++      D G Y C A N +G  RS +A L+   + E F L+  ++ S 
Sbjct: 422 RYTISGGNLIIYEPKQALDQGAYHCVAENKFGRIRSESAHLNFGFIME-FNLKRSAETSE 480

Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
                 + C PP+  P+   YW ++      + D R+ +   G L        D   Y C
Sbjct: 481 MNWGKSIFCDPPQHYPDVRYYWARDYFPNFVEEDQRVFVSRDGALYFSFIETVDRANYSC 540

Query: 181 IARNAAGT--RESAIATLKI----HIKPYLITG------PEDVVAQTGSSVTFQCRVGGD 228
             +       R      L++    + +  +         PE  VA  G  +  +C   G 
Sbjct: 541 TVQTLVSDTGRNGPFFPLRVTPNSNYQALIFANTFPKVFPEAPVA--GDEIRLECMAFGY 598

Query: 229 PLPDVLWRRSAGGGNMPLGR-VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGY 286
           P+P   W R      +PL R    ++ G  L + N    D GEYSC   N    +  S Y
Sbjct: 599 PIPSYNWTRQG----LPLQRNAYTINYGRVLIIQNATTNDNGEYSCTITNPRKTLMKSIY 654

Query: 287 LTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHA 346
           + +   P   +    +  +  +   F C A   P+    W     R +    ++RD+Y  
Sbjct: 655 INIQMRPQFTIPLKDMIKDYNSDVTFICEAFAIPDANYTWYKNAER-LDPANINRDRY-- 711

Query: 347 TAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN 406
             + D V  +   + DK+D+     C A N   +SF   +L V S     P    +   +
Sbjct: 712 -IIQDNVLTIKFLEKDKDDAMYQ--CGAQNQLKTSFSSAQLRVLS---MKPSFKKHPLES 765

Query: 407 QTLPI-KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465
           +   +        C     P P   W  +G+ +     R +   GTL +    + D G Y
Sbjct: 766 EVYAVYNGNTTIVCDPEAAPRPKFQWKKDGQVIGSGGHRRILPSGTLTISPTSRDDEGIY 825

Query: 466 TCVASSRHG 474
           TC+AS++ G
Sbjct: 826 TCIASNQAG 834



 Score = 91.5 bits (217), Expect = 1e-16
 Identities = 66/234 (28%), Positives = 111/234 (47%), Gaps = 17/234 (7%)

Query: 79  DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSA--QGDTVVLECLPPRGS 135
           D  +Y C A N   T+ S +A L V  ++  F+  P ES+  A   G+T ++ C  P  +
Sbjct: 728 DDAMYQCGAQNQLKTSFS-SAQLRVLSMKPSFKKHPLESEVYAVYNGNTTIV-C-DPEAA 784

Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195
           P P   WKK+GQ +   G  R  ++  G L I    + D G Y CIA N AGT ES    
Sbjct: 785 PRPKFQWKKDGQVIGSGGHRR--ILPSGTLTISPTSRDDEGIYTCIASNQAGTDESHARV 842

Query: 196 LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV--LWRRSA---GGGNMPLGRVK 250
           + +    ++ T P+ +V++    +   C    D L D+  +W+ +       +   GR+ 
Sbjct: 843 IVLQEIRFIETPPQRIVSKEHDLIFLHCEAAFDELLDIAYVWKHNGEVLKNNHDGTGRI- 901

Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
           ++D   L + N  + D G+Y C  +++V  +S+   +++   P    +P  V V
Sbjct: 902 IVDWNRLTVHNTSMRDAGDYECVVKSAVNEISSKTSVSIEGAPG---APGGVQV 952



 Score = 82.6 bits (195), Expect = 6e-14
 Identities = 156/719 (21%), Positives = 261/719 (36%), Gaps = 74/719 (10%)

Query: 122  GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQC 180
            GD + LEC+   G P P+  W + G  L        + ++ G  L+IQ+A   D G Y C
Sbjct: 586  GDEIRLECMA-FGYPIPSYNWTRQGLPL----QRNAYTINYGRVLIIQNATTNDNGEYSC 640

Query: 181  IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA- 239
               N   T   +I  + I ++P      +D++    S VTF C     P  +  W ++A 
Sbjct: 641  TITNPRKTLMKSIY-INIQMRPQFTIPLKDMIKDYNSDVTFICEAFAIPDANYTWYKNAE 699

Query: 240  --GGGNMPLGRVKVLDDGSLRLDNVIL-ADEGEYSCEAENSVGAVSASGYLTVYD-PPSI 295
                 N+   R  ++ D  L +  +    D+  Y C A+N +    +S  L V    PS 
Sbjct: 700  RLDPANINRDRY-IIQDNVLTIKFLEKDKDDAMYQCGAQNQLKTSFSSAQLRVLSMKPSF 758

Query: 296  NLSP---NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
               P       V +GN     C     P P   W  +G   +I  G      H   +  G
Sbjct: 759  KKHPLESEVYAVYNGNTT-IVCDPEAAPRPKFQWKKDGQ--VIGSG-----GHRRILPSG 810

Query: 353  VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
               LTI+ T ++D      C A N AG+     ++ V  +       I   P        
Sbjct: 811  --TLTISPTSRDD-EGIYTCIASNQAGTDESHARVIVLQE----IRFIETPPQRIVSKEH 863

Query: 413  SMAVFPCTAICTPEPIIA--WYFEGEALIQNH---RRNVTNDGTLVLKDLDKSDSGTYTC 467
             +    C A       IA  W   GE L  NH    R + +   L + +    D+G Y C
Sbjct: 864  DLIFLHCEAAFDELLDIAYVWKHNGEVLKNNHDGTGRIIVDWNRLTVHNTSMRDAGDYEC 923

Query: 468  VASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527
            V               V S +N  I    +  +   PG P       ++ T   + W   
Sbjct: 924  V---------------VKSAVN-EISSKTSVSIEGAPGAPGGVQVIQISKTKAIIEWVDG 967

Query: 528  NKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIV 587
            +  G  +I  Y +   +    +  N   + +   V      Q   VV +L P   Y F V
Sbjct: 968  SHNG-RAIRYYNILGRTNWNRTWVNVSTHVQAREVDRYTSRQQAEVV-NLTPWSAYEFSV 1025

Query: 588  RTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSK 647
               N  G+  PS  S   +  +D   +        +       + D  +      P +  
Sbjct: 1026 TAVNDLGIGTPSAPSPIYSTYEDKPYI-----APRNVGGGGGKIGDLTITWDPLLPQEQH 1080

Query: 648  TIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFL 707
            +  + +++  F+ L+G   +    D I  +  M   + +  ++ +       YT+YE  +
Sbjct: 1081 SHGIHYKV--FWKLKGAIEW--ASDEIKKQDHMGVAVVNIPLNNY-------YTEYEVKV 1129

Query: 708  IPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQN--GIIT 765
                   +G  S   V  + +D+P   P        N+T  ++ W P ++  +N  G + 
Sbjct: 1130 QAINSVGKGPESEIAVIHSAEDMPQVAPQKPIALAYNSTCFNVTWQPIDMSRENIRGKLI 1189

Query: 766  GYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQK 824
            G+ +   W      +  V   +   +  +LI+  L     Y V++ A    G GP S++
Sbjct: 1190 GHRLKY-WKTTHQEEDSVYYLSRTTRNWALIV-GLQPDTYYFVKVMAYNAAGEGPESER 1246



 Score = 73.3 bits (172), Expect = 4e-11
 Identities = 52/161 (32%), Positives = 75/161 (46%), Gaps = 13/161 (8%)

Query: 30  TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
           T+ C    +P P  +W K G ++ S  HR ILP+G L     +      D G+Y C A+N
Sbjct: 776 TIVCDPEAAPRPKFQWKKDGQVIGSGGHRRILPSGTLTISPTS----RDDEGIYTCIASN 831

Query: 90  SYGTARSRNATLHVAVLREEFRLE--PESKQSAQGDTVVLECLPPRGSPEPNVY-WKKNG 146
             GT  S      V VL+E   +E  P+   S + D + L C           Y WK NG
Sbjct: 832 QAGTDESH---ARVIVLQEIRFIETPPQRIVSKEHDLIFLHCEAAFDELLDIAYVWKHNG 888

Query: 147 QTLL--FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
           + L    DG  R+ +VD   L + +    DAG Y+C+ ++A
Sbjct: 889 EVLKNNHDGTGRI-IVDWNRLTVHNTSMRDAGDYECVVKSA 928



 Score = 43.2 bits (97), Expect = 0.044
 Identities = 33/132 (25%), Positives = 59/132 (44%), Gaps = 7/132 (5%)

Query: 694  ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
            I  L+  T Y   ++ +    EG  S     +T    P  PP ++ ++ +N +TV + W 
Sbjct: 1219 IVGLQPDTYYFVKVMAYNAAGEGPESERFEERTYRKAPQKPPSSVHVYGINPSTVRVVWR 1278

Query: 754  PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTV---HQATSLIMTNLTSGVSYSVQI 810
                      + GY V + W    ++++M+  N T+    Q     + NLT G SY++++
Sbjct: 1279 YVSPSQDEEPVEGYKVRI-W---ESDQNMITANNTIVPIGQKLESYINNLTPGKSYNMRV 1334

Query: 811  AAETIIGLGPFS 822
             A +  G G  S
Sbjct: 1335 LAYSNGGDGRMS 1346


>UniRef50_UPI0000519A30 Cluster: PREDICTED: similar to Peroxidasin
           CG12002-PA, isoform A; n=2; Apocrita|Rep: PREDICTED:
           similar to Peroxidasin CG12002-PA, isoform A - Apis
           mellifera
          Length = 1293

 Score =  124 bits (300), Expect = 1e-26
 Identities = 89/292 (30%), Positives = 131/292 (44%), Gaps = 15/292 (5%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P I+  P DV V      +  C   G P P I+W +    V +D +  ++   G   +  
Sbjct: 237 PRIMNGPQDVEVRLGGTISFTCEVIGDPIPEIKWMRDSNEVSADGNHYVIQEDGTLIISD 296

Query: 72  THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECL 130
                  D G Y C A +  G  +SR A   + V     F   PES+    G  V   C 
Sbjct: 297 V---TEQDTGEYECVAKSEMGLTKSRKARAVITVSPSLRFTELPESQTVQIGVDVSFTC- 352

Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTR 189
              G P PN+ W +NGQ L   G  R+ + + G+L+ I   ++TD  RY C ARN+ G  
Sbjct: 353 KVDGRPTPNIQWWRNGQLLNVGG--RVAIENEGSLLKIFAVKETDTARYVCQARNSNGYA 410

Query: 190 ESAIATLKI----HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
           E++ A L +    +  P +   P D+ A+ G+ +   CRV G P P + W++   G  M 
Sbjct: 411 ETS-ADLNVVDESYSPPRMTYEPHDMEAEPGTIIEVPCRVEGVPKPVIQWKKD--GTAME 467

Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
             R ++   GSL L NV   D G Y C A N  G  +A   + V  P + ++
Sbjct: 468 GERFRISRGGSLYLYNVTAGDTGRYECSAVNQYGRATAQALVRVRQPEATDV 519



 Score =  123 bits (297), Expect = 3e-26
 Identities = 81/300 (27%), Positives = 139/300 (46%), Gaps = 14/300 (4%)

Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLD 260
           +P ++ GP+DV  + G +++F C V GDP+P++ W R +   +       + +DG+L + 
Sbjct: 236 EPRIMNGPQDVEVRLGGTISFTCEVIGDPIPEIKWMRDSNEVSADGNHYVIQEDGTLIIS 295

Query: 261 NVILADEGEYSCEAENSVGAV-SASGYLTVYDPPSINLS--PNSVNVESGNVARFTCTAT 317
           +V   D GEY C A++ +G   S      +   PS+  +  P S  V+ G    FTC   
Sbjct: 296 DVTEQDTGEYECVAKSEMGLTKSRKARAVITVSPSLRFTELPESQTVQIGVDVSFTCKVD 355

Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
           GRP P + W   G   ++  G         A+ +  ++L I    + D+    VC A N 
Sbjct: 356 GRPTPNIQWWRNGQ--LLNVG------GRVAIENEGSLLKIFAVKETDTAR-YVCQARNS 406

Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437
            G +     L V  D+   PP +T  P +      ++   PC     P+P+I W  +G A
Sbjct: 407 NGYAETSADLNVV-DESYSPPRMTYEPHDMEAEPGTIIEVPCRVEGVPKPVIQWKKDGTA 465

Query: 438 LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRA 497
           + +  R  ++  G+L L ++   D+G Y C A +++G+      + V  P   ++   RA
Sbjct: 466 M-EGERFRISRGGSLYLYNVTAGDTGRYECSAVNQYGRATAQALVRVRQPEATDVLVIRA 524



 Score =  118 bits (283), Expect = 1e-24
 Identities = 76/247 (30%), Positives = 116/247 (46%), Gaps = 15/247 (6%)

Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT 173
           P+  +   G T+   C    G P P + W ++   +  DG+  + + + G L+I D  + 
Sbjct: 243 PQDVEVRLGGTISFTC-EVIGDPIPEIKWMRDSNEVSADGNHYV-IQEDGTLIISDVTEQ 300

Query: 174 DAGRYQCIARNAAGTRESAIATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLP 231
           D G Y+C+A++  G  +S  A   I + P L     PE    Q G  V+F C+V G P P
Sbjct: 301 DTGEYECVAKSEMGLTKSRKARAVITVSPSLRFTELPESQTVQIGVDVSFTCKVDGRPTP 360

Query: 232 DVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTV- 289
           ++ W R+    N+  GRV + ++GS L++  V   D   Y C+A NS G    S  L V 
Sbjct: 361 NIQWWRNGQLLNVG-GRVAIENEGSLLKIFAVKETDTARYVCQARNSNGYAETSADLNVV 419

Query: 290 ---YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW-----SVEGNRTIIFPGMSR 341
              Y PP +   P+ +  E G +    C   G P+P + W     ++EG R  I  G S 
Sbjct: 420 DESYSPPRMTYEPHDMEAEPGTIIEVPCRVEGVPKPVIQWKKDGTAMEGERFRISRGGSL 479

Query: 342 DKYHATA 348
             Y+ TA
Sbjct: 480 YLYNVTA 486


>UniRef50_UPI0000D560FB Cluster: PREDICTED: similar to CG1084-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG1084-PA - Tribolium castaneum
          Length = 1192

 Score =  124 bits (298), Expect = 2e-26
 Identities = 118/498 (23%), Positives = 190/498 (38%), Gaps = 45/498 (9%)

Query: 12  PYIIEQPLDVTVAR-----HQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP---- 62
           PY I+QP+D T        +   +L+C AGG P+P   W++    +     R I P    
Sbjct: 251 PYFIKQPVDATFDSSKKMLYNDISLSCLAGGFPTPTYEWFREDYEIDKLVARRIDPLSDP 310

Query: 63  ----AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESK 117
               +GG+  +     +   D   Y C+A+N +GT  S +  L+   ++E   +  PES 
Sbjct: 311 RYTISGGMLIIHEPEEK--RDHATYHCKASNKFGTIISESVQLNFGFIKEFVLKRSPESG 368

Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR 177
               G  +   C PP   P     W ++      + D R+ +   G L        D   
Sbjct: 369 DKNWGKAIY--CDPPNHFPSVRYSWSRDYFPNFVEEDRRVFVSYDGALYFSALETIDKAN 426

Query: 178 YQCIARN--AAGTRESAIATLKI--HIKPYLITGPEDVVAQ------TGSSVTFQCRVGG 227
           Y C  ++  +   R      L +  H     +  P +           G  V  +C   G
Sbjct: 427 YSCSVQSEFSDSGRNGPFFPLMVNPHSHYQQLKFPNNFPKAFPDAPIAGKEVRLECMAFG 486

Query: 228 DPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYL 287
            P+P   W R   G  +P   V    +  L + +V + D+GEY C A N   +   S  L
Sbjct: 487 YPVPSYNWTRR--GAPLPRSAVLSSFNRVLTIPHVQVEDQGEYVCRAYNDRASTENSLIL 544

Query: 288 TVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
            +   P+  +     + +S +   +TC A G P+    W   G +      + RD+    
Sbjct: 545 NIQAEPNFTIPLADRHADSKSELVWTCEAFGIPDVNYTWWKNGRQ------LERDRIR-- 596

Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407
            + D V  LTI   D+        C A N   + +   +L V +     P    +    +
Sbjct: 597 -IQDNV--LTIRYLDQERDPGMYQCRATNSLKTKYSSAQLRVLAFR---PTFKKHPLEAE 650

Query: 408 TLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYT 466
           T   +  +V   C     P P   W  +G  L     R +  +G LV+  + + D G YT
Sbjct: 651 TYAAEGGSVTIKCNPEAAPRPEFVWKKDGNVLGSGGHRRILENGNLVISSVSRDDEGQYT 710

Query: 467 CVASSRHGKYVWSGALLV 484
           C AS++ G     G L+V
Sbjct: 711 CRASNQFGVDESKGRLIV 728



 Score =  100 bits (239), Expect = 3e-19
 Identities = 80/270 (29%), Positives = 117/270 (43%), Gaps = 19/270 (7%)

Query: 33  CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
           C A G P     W+K G  +  D  R       +  +R        D G+Y C ATNS  
Sbjct: 571 CEAFGIPDVNYTWWKNGRQLERDRIRI---QDNVLTIRYLDQE--RDPGMYQCRATNSLK 625

Query: 93  TARSRNATLHVAVLREEFRLEPESKQS--AQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
           T  S +A L V   R  F+  P   ++  A+G +V ++C  P  +P P   WKK+G  L 
Sbjct: 626 TKYS-SAQLRVLAFRPTFKKHPLEAETYAAEGGSVTIKC-NPEAAPRPEFVWKKDGNVLG 683

Query: 151 FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG-PE 209
             G  R  +++ GNLVI    + D G+Y C A N  G  ES    L +   P LI     
Sbjct: 684 SGGHRR--ILENGNLVISSVSRDDEGQYTCRASNQFGVDESK-GRLIVLRGPRLIESLTP 740

Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL------DDGSLRLDNVI 263
            +V   G     +C    + + D+ +  S  G  +    +K +      D G L + N  
Sbjct: 741 KIVTTVGRYFDLRCLAETEEMLDIAYVWSHNGIKIRDIDIKNMNYRLRIDGGFLSVTNAT 800

Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPP 293
             D GEY C  +++VG +S+   + V  PP
Sbjct: 801 FTDAGEYECTIKSTVGKISSRSVVVVEGPP 830



 Score = 91.9 bits (218), Expect = 1e-16
 Identities = 76/276 (27%), Positives = 120/276 (43%), Gaps = 16/276 (5%)

Query: 31  LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
           L C A G P P+  W + G    +   RS + +     L   H +V  D G Y C A N 
Sbjct: 480 LECMAFGYPVPSYNWTRRG----APLPRSAVLSSFNRVLTIPHVQVE-DQGEYVCRAYND 534

Query: 91  YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
              A + N+ +        F +    + +     +V  C    G P+ N  W KNG+ L 
Sbjct: 535 --RASTENSLILNIQAEPNFTIPLADRHADSKSELVWTC-EAFGIPDVNYTWWKNGRQLE 591

Query: 151 FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP-- 208
            D   R+ + D    +    ++ D G YQC A N+  T+ S+     +  +P     P  
Sbjct: 592 RD---RIRIQDNVLTIRYLDQERDPGMYQCRATNSLKTKYSSAQLRVLAFRPTFKKHPLE 648

Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268
            +  A  G SVT +C     P P+ +W++  G      G  ++L++G+L + +V   DEG
Sbjct: 649 AETYAAEGGSVTIKCNPEAAPRPEFVWKKD-GNVLGSGGHRRILENGNLVISSVSRDDEG 707

Query: 269 EYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSV 302
           +Y+C A N  G   + G L V   P +  +L+P  V
Sbjct: 708 QYTCRASNQFGVDESKGRLIVLRGPRLIESLTPKIV 743



 Score = 60.5 bits (140), Expect = 3e-07
 Identities = 50/182 (27%), Positives = 72/182 (39%), Gaps = 11/182 (6%)

Query: 12  PYIIEQPLDVTV--ARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
           P   + PL+     A     T+ C    +P P   W K G ++ S  HR IL  G L   
Sbjct: 640 PTFKKHPLEAETYAAEGGSVTIKCNPEAAPRPEFVWKKDGNVLGSGGHRRILENGNLVIS 699

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
             +      D G Y C A+N +G   S+   + +   R    L P+   +  G    L C
Sbjct: 700 SVS----RDDEGQYTCRASNQFGVDESKGRLIVLRGPRLIESLTPKIVTTV-GRYFDLRC 754

Query: 130 LPPRGSPEPNVY-WKKNGQTLLFDGDSRMHL---VDGGNLVIQDARQTDAGRYQCIARNA 185
           L          Y W  NG  +       M+    +DGG L + +A  TDAG Y+C  ++ 
Sbjct: 755 LAETEEMLDIAYVWSHNGIKIRDIDIKNMNYRLRIDGGFLSVTNATFTDAGEYECTIKST 814

Query: 186 AG 187
            G
Sbjct: 815 VG 816


>UniRef50_UPI0000D55944 Cluster: PREDICTED: similar to CG8967-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG8967-PA - Tribolium castaneum
          Length = 1094

 Score =  123 bits (297), Expect = 3e-26
 Identities = 116/416 (27%), Positives = 172/416 (41%), Gaps = 33/416 (7%)

Query: 78  SDAGVYWCEATNSYGTARSRNATLHVAVLREE---FRLEPESKQSAQGDTVVLECLPPRG 134
           SD GVY C A N+ G AR       +AV  EE    ++ P  +   QG T   +C   + 
Sbjct: 183 SDNGVYRCLANNTAG-ARYSTTNFALAVAGEETALIQVVPRDQLVPQGGTAYFDCQYQQA 241

Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR--ESA 192
                 Y+KK+ + L  +   +  +   G L I D +  D G Y C+   +  T   +S 
Sbjct: 242 EVT-EWYFKKDTRPL--ENGKKFVIHSNGTLQINDVQGKDQGFYSCVGIRSESTEIPQSY 298

Query: 193 IATLKI---------HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
           IA LK+           +P L      VVA  G      C       P   W  + GG  
Sbjct: 299 IAELKLAYLSEFTVNSFEPPLSENSNQVVAPEGGLFQLTCLEPDSLPPAKKWWLNTGGHT 358

Query: 244 MP-LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
           +   G V+V DDG L ++ V +   G Y+C AEN  G       L V + P +   P SV
Sbjct: 359 VSDSGEVRV-DDGRLIIEKVRMDHAGNYTCVAENMAGKTEKIIELVVLNKPVVTAQPLSV 417

Query: 303 NVESGNVARFTCTATGRPEPTMF-WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
            V+    +  TC    +   T+  W  +G       G +        +F     L I +T
Sbjct: 418 TVDENEPSMLTCDYEPKNHFTIVKWRKDGKSLRHDFGENSLDRQRIKIFKHNASLVIRET 477

Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR---PPPIITNGPSNQTLPIKSMAVFP 418
           + +D R   VC  +       +    T++  +     PPP+      N+ L + S+A   
Sbjct: 478 ESHD-RGEYVCEVLAKGFEPVLSEPATISVIEKLKFVPPPV------NKKLELGSVAKVH 530

Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
           C A  TP PII W   GE+   ++ R ++ +GTLV   +   D G YTCVA++  G
Sbjct: 531 CKAQGTPPPIITWEKLGESF--DNSRIISMNGTLVFNGVLNEDKGKYTCVATNSQG 584



 Score =  103 bits (247), Expect = 3e-20
 Identities = 79/276 (28%), Positives = 125/276 (45%), Gaps = 15/276 (5%)

Query: 12  PYIIEQPLDVTVARHQPATLNCR-AGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
           P +  QPL VTV  ++P+ L C     +    ++W K G  +  D   + L    +   +
Sbjct: 408 PVVTAQPLSVTVDENEPSMLTCDYEPKNHFTIVKWRKDGKSLRHDFGENSLDRQRIKIFK 467

Query: 71  ATHGRV-----HSDAGVYWCEA-TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
                V       D G Y CE     +    S  AT+ V + + +F   P +K+   G  
Sbjct: 468 HNASLVIRETESHDRGEYVCEVLAKGFEPVLSEPATISV-IEKLKFVPPPVNKKLELGSV 526

Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
             + C   +G+P P + W+K G++  FD +SR+  ++G  LV       D G+Y C+A N
Sbjct: 527 AKVHC-KAQGTPPPIITWEKLGES--FD-NSRIISMNG-TLVFNGVLNEDKGKYTCVATN 581

Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
           + G     I  + + + P     P++    T G SVT  C V GDP P + W ++    +
Sbjct: 582 SQGVINVTI-NIDVVVAPKFSVEPKNPTEVTEGQSVTIDCVVEGDPKPTIHWDKNLKMND 640

Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279
               R  VL++G+L +  V   DE +Y C A NS G
Sbjct: 641 FDHSRFTVLENGTLFISEVHREDENKYGCTAGNSAG 676



 Score =  102 bits (245), Expect = 5e-20
 Identities = 124/493 (25%), Positives = 188/493 (38%), Gaps = 52/493 (10%)

Query: 8   SGEAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWY-KGGVLVVSDTHRSILPAGG 65
           +GE   +I+  P D  V +   A  +C+     +    WY K     + +  + ++ + G
Sbjct: 210 AGEETALIQVVPRDQLVPQGGTAYFDCQY--QQAEVTEWYFKKDTRPLENGKKFVIHSNG 267

Query: 66  LFFLRATHGRVHSDAGVYWCEATNSYGTA--RSRNATLHVAVLRE------EFRLEPESK 117
              +    G+   D G Y C    S  T   +S  A L +A L E      E  L   S 
Sbjct: 268 TLQINDVQGK---DQGFYSCVGIRSESTEIPQSYIAELKLAYLSEFTVNSFEPPLSENSN 324

Query: 118 Q--SAQGDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTD 174
           Q  + +G    L CL P   P    +W    G T+   G+ R   VD G L+I+  R   
Sbjct: 325 QVVAPEGGLFQLTCLEPDSLPPAKKWWLNTGGHTVSDSGEVR---VDDGRLIIEKVRMDH 381

Query: 175 AGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGG-DPLPDV 233
           AG Y C+A N AG  E  I  + ++ KP +   P  V           C     +    V
Sbjct: 382 AGNYTCVAENMAGKTEKIIELVVLN-KPVVTAQPLSVTVDENEPSMLTCDYEPKNHFTIV 440

Query: 234 LWRRSA-------GGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCE--AENSVGAVSA 283
            WR+         G  ++   R+K+   + SL +      D GEY CE  A+     +S 
Sbjct: 441 KWRKDGKSLRHDFGENSLDRQRIKIFKHNASLVIRETESHDRGEYVCEVLAKGFEPVLSE 500

Query: 284 SGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDK 343
              ++V +       P +  +E G+VA+  C A G P P + W   G     F       
Sbjct: 501 PATISVIEKLKFVPPPVNKKLELGSVAKVHCKAQGTPPPIITWEKLGES---FDNSRIIS 557

Query: 344 YHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG 403
            + T VF+GV          N+ +    C A N  G   V   + V        P  +  
Sbjct: 558 MNGTLVFNGVL---------NEDKGKYTCVATNSQGVINVTINIDVVV-----APKFSVE 603

Query: 404 PSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKDLDKSD 461
           P N T   +  +V   C     P+P I W    +    +H R  V  +GTL + ++ + D
Sbjct: 604 PKNPTEVTEGQSVTIDCVVEGDPKPTIHWDKNLKMNDFDHSRFTVLENGTLFISEVHRED 663

Query: 462 SGTYTCVASSRHG 474
              Y C A +  G
Sbjct: 664 ENKYGCTAGNSAG 676



 Score = 87.0 bits (206), Expect = 3e-15
 Identities = 101/409 (24%), Positives = 167/409 (40%), Gaps = 33/409 (8%)

Query: 1   MSDDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRS 59
           +S+  V S E P + E    V         L C    S  PA +W+   G   VSD+   
Sbjct: 307 LSEFTVNSFEPP-LSENSNQVVAPEGGLFQLTCLEPDSLPPAKKWWLNTGGHTVSDSGEV 365

Query: 60  ILPAGGLFFLRATHGRVHSD-AGVYWCEATNSYGTARSRNATLHVAVLREEF-RLEPESK 117
            +  G L        +V  D AG Y C A N  G        + + VL +     +P S 
Sbjct: 366 RVDDGRLII-----EKVRMDHAGNYTCVAENMAGKTEK---IIELVVLNKPVVTAQPLSV 417

Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFD-GDSRMH------LVDGGNLVIQDA 170
              + +  +L C     +    V W+K+G++L  D G++ +            +LVI++ 
Sbjct: 418 TVDENEPSMLTCDYEPKNHFTIVKWRKDGKSLRHDFGENSLDRQRIKIFKHNASLVIRET 477

Query: 171 RQTDAGRYQC-IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP 229
              D G Y C +         S  AT+ +  K   +  P +   + GS     C+  G P
Sbjct: 478 ESHDRGEYVCEVLAKGFEPVLSEPATISVIEKLKFVPPPVNKKLELGSVAKVHCKAQGTP 537

Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
            P + W +   G +    R+ +  +G+L  + V+  D+G+Y+C A NS G ++ +  + V
Sbjct: 538 PPIITWEKL--GESFDNSRI-ISMNGTLVFNGVLNEDKGKYTCVATNSQGVINVTINIDV 594

Query: 290 YDPPSINLSP-NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
              P  ++ P N   V  G      C   G P+PT+ W    ++ +        ++  T 
Sbjct: 595 VVAPKFSVEPKNPTEVTEGQSVTIDCVVEGDPKPTIHW----DKNLKMNDFDHSRF--TV 648

Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397
           + +G   L I++  + D  N   C+A N AG +    +L V S D   P
Sbjct: 649 LENG--TLFISEVHRED-ENKYGCTAGNSAGLNRQEVQLIVHSRDGYHP 694



 Score = 78.6 bits (185), Expect = 1e-12
 Identities = 119/496 (23%), Positives = 195/496 (39%), Gaps = 59/496 (11%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
           V   E PY  E P +V V + +  TL C+          W   G  + + T R       
Sbjct: 17  VIGKEDPYFSESPRNVDVVQGKSVTLPCKVTPGIGMTYYWELNGSKIANTTRRH-QQGSN 75

Query: 66  LFFLRATHGRVHSDAGVYWCEATNS----YGTARSRNATLHVAVLRE-EFRL-EPESKQ- 118
           L   R    R   D+G + C A +S     G+ RS  A+L++  + E   +L EPES   
Sbjct: 76  LHITRVDRER---DSGQFTCIAEDSTSSLAGSIRSSEASLNIQWIDEVSVQLQEPESASF 132

Query: 119 SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY 178
            ++G  V L C     S + +  W +N   LL    S    +    L I++   +D G Y
Sbjct: 133 ISRGSDVTLRC-HTDASGDVHYEWFRNSDRLL---KSDKIEIKKKRLHIKNVGPSDNGVY 188

Query: 179 QCIARNAAGTRESA--IATLKIHIKPYLI-TGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
           +C+A N AG R S    A      +  LI   P D +   G +  F C+     + +  W
Sbjct: 189 RCLANNTAGARYSTTNFALAVAGEETALIQVVPRDQLVPQGGTAYFDCQYQQAEVTE--W 246

Query: 236 RRSAGGGNMPLGRVKVL-DDGSLRLDNVILADEGEYSC--------EAENSVGAVSASGY 286
                   +  G+  V+  +G+L++++V   D+G YSC        E   S  A     Y
Sbjct: 247 YFKKDTRPLENGKKFVIHSNGTLQINDVQGKDQGFYSCVGIRSESTEIPQSYIAELKLAY 306

Query: 287 LTVYD----PPSINLSPNSVNVESGNVARFTC-TATGRPEPTMFWSVEGNRTIIFPGMSR 341
           L+ +      P ++ + N V    G + + TC      P    +W   G  T+   G  R
Sbjct: 307 LSEFTVNSFEPPLSENSNQVVAPEGGLFQLTCLEPDSLPPAKKWWLNTGGHTVSDSGEVR 366

Query: 342 DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401
                  V DG  ++   +  + D      C A N AG +    +L V +      P++T
Sbjct: 367 -------VDDGRLII---EKVRMDHAGNYTCVAENMAGKTEKIIELVVLN-----KPVVT 411

Query: 402 NGPSNQTLPIKSMAVFPCTAICTPE-PIIAWYFEGEALIQNHRRN---------VTNDGT 451
             P + T+     ++  C         I+ W  +G++L  +   N           ++ +
Sbjct: 412 AQPLSVTVDENEPSMLTCDYEPKNHFTIVKWRKDGKSLRHDFGENSLDRQRIKIFKHNAS 471

Query: 452 LVLKDLDKSDSGTYTC 467
           LV+++ +  D G Y C
Sbjct: 472 LVIRETESHDRGEYVC 487


>UniRef50_A7RGL7 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 553

 Score =  123 bits (297), Expect = 3e-26
 Identities = 116/387 (29%), Positives = 163/387 (42%), Gaps = 28/387 (7%)

Query: 105 VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN 164
           +LR E       K  A+ D    E L      EP+V W +N   ++ DG SR    DG  
Sbjct: 179 ILRSEEEDAGSYKCLARNDVGSAERLFEVQVEEPSVTWYRNKNEIVPDGRSRTTF-DGET 237

Query: 165 --LVIQDARQTDAGRYQCIARNAAGTRE-SAIATLKIHIKPYLITGPEDVVAQTGSSVTF 221
             L++QD +  DAG+Y+CIA N  G    +A  T+     P  ++    +    G +V++
Sbjct: 238 YKLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKREAPVFVSKLRPLFVTEGDNVSW 297

Query: 222 QCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDG---SLRLDNVILADEGEYSCEAE 275
            C+V G P P V W R     N PL    R K+  DG   SL L      D+G Y+C   
Sbjct: 298 MCKVAGMPRPTVEWYRD----NQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVIT 353

Query: 276 NSVGAVSASGYLTV---YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332
           NS G+  +S  L V    + P +    N V    G  ARF    +G P P + W     +
Sbjct: 354 NSAGSAFSSAELQVDKKANKPKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSIK 413

Query: 333 TIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD 392
                  +  ++H +   D  + LTI DT   D+  T  C A N  G    RG L V   
Sbjct: 414 V-----RNESRFHLSEDGDRYS-LTITDTKLVDT-GTYKCVATNEGGKITSRGDLDVRER 466

Query: 393 DDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG- 450
              P     +      +  +S A+ F       P P I WY +GE +    R  + + G 
Sbjct: 467 QFAPEFYGDDELKEPVVVQESDAINFKVRVRGKPVPTIVWYKDGEMVRDVRRFEIRSRGD 526

Query: 451 --TLVLKDLDKSDSGTYTCVASSRHGK 475
             T         D+GTYTC AS++ GK
Sbjct: 527 IYTFATYSASAEDAGTYTCEASNKLGK 553



 Score =  115 bits (277), Expect = 7e-24
 Identities = 126/491 (25%), Positives = 202/491 (41%), Gaps = 59/491 (12%)

Query: 9   GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
           G+ P  + +   + +       L+C   G P P ++W++  VL+           G +  
Sbjct: 13  GDTPTFMSKLEPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSA 72

Query: 69  LRATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVL 127
           L      +  D GVY C  TN++G+  S+ + T+    LR E    P  ++    + + +
Sbjct: 73  LTVKEAELDDD-GVYKCVVTNNFGSVSSKADVTVLKKHLRPERDYAPIFEEKQFLEPLEI 131

Query: 128 ECLPP-------RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG---NLVIQDARQTDAGR 177
           +   P       RG P+P V W KNG+ L  DG   + +  GG    L I  + + DAG 
Sbjct: 132 QVRQPVEVSYHVRGRPKPTVTWWKNGKELR-DG-KHVEIRSGGTYHTLYILRSEEEDAGS 189

Query: 178 YQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
           Y+C+ARN  G   SA    ++ ++                SVT+  R   + +PD   R 
Sbjct: 190 YKCLARNDVG---SAERLFEVQVEE--------------PSVTWY-RNKNEIVPDGRSRT 231

Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV--YDPPSI 295
           +  G    L    +L D       + + D G+Y C A N +G    +  +TV   + P  
Sbjct: 232 TFDGETYKL----ILQD-------IKIKDAGQYECIASNPIGKAFCTAEMTVNKREAPVF 280

Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG-VT 354
                 + V  G+   + C   G P PT+ W    N+ +      R        FDG V 
Sbjct: 281 VSKLRPLFVTEGDNVSWMCKVAGMPRPTVEW-YRDNQPL------RADTRWKMDFDGRVC 333

Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
            L +++ D  D +    C   N AGS+F   +L V    ++ P +I      QT+   + 
Sbjct: 334 SLFLSEADCKD-KGVYNCVITNSAGSAFSSAELQVDKKANK-PKVIEKMNDVQTVE-GTE 390

Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASS 471
           A F       P P + WY     +    R +++ DG   +L + D    D+GTY CVA++
Sbjct: 391 ARFDVRFSGLPRPEVTWYRNSIKVRNESRFHLSEDGDRYSLTITDTKLVDTGTYKCVATN 450

Query: 472 RHGKYVWSGAL 482
             GK    G L
Sbjct: 451 EGGKITSRGDL 461



 Score = 91.5 bits (217), Expect = 1e-16
 Identities = 77/287 (26%), Positives = 123/287 (42%), Gaps = 19/287 (6%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
           V   EAP  + +   + V      +  C+  G P P + WY+    + +DT   +   G 
Sbjct: 272 VNKREAPVFVSKLRPLFVTEGDNVSWMCKVAGMPRPTVEWYRDNQPLRADTRWKMDFDGR 331

Query: 66  LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL--EPESKQSAQGD 123
           +  L  +      D GVY C  TNS G+A S +A L V     + ++  +    Q+ +G 
Sbjct: 332 VCSLFLSEADC-KDKGVYNCVITNSAGSAFS-SAELQVDKKANKPKVIEKMNDVQTVEGT 389

Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG---NLVIQDARQTDAGRYQC 180
               + +   G P P V W +N  ++    +SR HL + G   +L I D +  D G Y+C
Sbjct: 390 EARFD-VRFSGLPRPEVTWYRN--SIKVRNESRFHLSEDGDRYSLTITDTKLVDTGTYKC 446

Query: 181 IARNAAG--TRESAIATLKIHIKPYLITG---PEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
           +A N  G  T    +   +    P         E VV Q   ++ F+ RV G P+P ++W
Sbjct: 447 VATNEGGKITSRGDLDVRERQFAPEFYGDDELKEPVVVQESDAINFKVRVRGKPVPTIVW 506

Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILA---DEGEYSCEAENSVG 279
            +  G     + R ++   G +       A   D G Y+CEA N +G
Sbjct: 507 YKD-GEMVRDVRRFEIRSRGDIYTFATYSASAEDAGTYTCEASNKLG 552



 Score = 90.2 bits (214), Expect = 3e-16
 Identities = 89/311 (28%), Positives = 129/311 (41%), Gaps = 33/311 (10%)

Query: 41  PAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG-------- 92
           P++ WY+    +V D        G  + L     ++  DAG Y C A+N  G        
Sbjct: 212 PSVTWYRNKNEIVPDGRSRTTFDGETYKLILQDIKI-KDAGQYECIASNPIGKAFCTAEM 270

Query: 93  TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFD 152
           T   R A + V+ LR  F  E        GD V   C    G P P V W ++ Q L  D
Sbjct: 271 TVNKREAPVFVSKLRPLFVTE--------GDNVSWMC-KVAGMPRPTVEWYRDNQPLRAD 321

Query: 153 GDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGTRESA--IATLKIHIKPYLITGP 208
              +M   DG   +L + +A   D G Y C+  N+AG+  S+  +   K   KP +I   
Sbjct: 322 TRWKMDF-DGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKANKPKVIEKM 380

Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---SLRLDNVILA 265
            DV    G+   F  R  G P P+V W R++        R  + +DG   SL + +  L 
Sbjct: 381 NDVQTVEGTEARFDVRFSGLPRPEVTWYRNSIKVRNE-SRFHLSEDGDRYSLTITDTKLV 439

Query: 266 DEGEYSCEAENSVGAVSASGYLTVYD---PPSI---NLSPNSVNVESGNVARFTCTATGR 319
           D G Y C A N  G +++ G L V +    P     +     V V+  +   F     G+
Sbjct: 440 DTGTYKCVATNEGGKITSRGDLDVRERQFAPEFYGDDELKEPVVVQESDAINFKVRVRGK 499

Query: 320 PEPTMFWSVEG 330
           P PT+ W  +G
Sbjct: 500 PVPTIVWYKDG 510



 Score = 53.6 bits (123), Expect = 3e-05
 Identities = 49/188 (26%), Positives = 71/188 (37%), Gaps = 13/188 (6%)

Query: 321 EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGS 380
           EP++ W    N  I+  G SR        FDG T   I    K        C A N  G 
Sbjct: 211 EPSVTWYRNKNE-IVPDGRSR------TTFDGETYKLILQDIKIKDAGQYECIASNPIGK 263

Query: 381 SFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ 440
           +F   ++TV     R  P+  +      +       + C     P P + WY + + L  
Sbjct: 264 AFCTAEMTVNK---REAPVFVSKLRPLFVTEGDNVSWMCKVAGMPRPTVEWYRDNQPLRA 320

Query: 441 NHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRA 497
           + R  +  DG   +L L + D  D G Y CV ++  G    S  L VD   N      + 
Sbjct: 321 DTRWKMDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKANKPKVIEKM 380

Query: 498 ADVSSLPG 505
            DV ++ G
Sbjct: 381 NDVQTVEG 388



 Score = 43.2 bits (97), Expect = 0.044
 Identities = 40/154 (25%), Positives = 60/154 (38%), Gaps = 15/154 (9%)

Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250
           S +A  K    P  ++  E +    G      C V G P P+V W R       P  R K
Sbjct: 5   SLLALQKKGDTPTFMSKLEPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIK-PSRRFK 63

Query: 251 VLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP---PSINLSP----- 299
              DG+   L +    L D+G Y C   N+ G+VS+   +TV      P  + +P     
Sbjct: 64  ASYDGNVSALTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKKHLRPERDYAPIFEEK 123

Query: 300 ---NSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
                + ++       +    GRP+PT+ W   G
Sbjct: 124 QFLEPLEIQVRQPVEVSYHVRGRPKPTVTWWKNG 157


>UniRef50_UPI00006A0696 Cluster: DDM36; n=4; Tetrapoda|Rep: DDM36 -
           Xenopus tropicalis
          Length = 932

 Score =  123 bits (296), Expect = 3e-26
 Identities = 131/474 (27%), Positives = 182/474 (38%), Gaps = 52/474 (10%)

Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
           NV WKK+G  L  D   R+ L +G  L+ Q  R    GRY C A+++ G       T+++
Sbjct: 32  NVTWKKDGVQLNSDEALRV-LRNGSLLISQMERDNIEGRYSCAAQDSVGIVTGRSHTVRL 90

Query: 199 HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGSL 257
              P     PE       S   F+C   G P P+V W++      +P   R   L  G L
Sbjct: 91  ASLPSFHQQPESQTVMLNSMARFECGFSGFPPPEVTWQKDQAP--VPAESRFLTLPTGVL 148

Query: 258 RLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPS---------INLSPNSVNVESG 307
           ++  V   DEG Y C A N + +  S+  +L+V    S         I  +P ++ VE G
Sbjct: 149 QISGVQEKDEGFYRCMATNILNSSYSSEAHLSVEQDASVYTLAEELTITRAPQNITVEEG 208

Query: 308 NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
           + A   C A G   P + W  E  + I     S D         G T L +       + 
Sbjct: 209 HSAIMECMAKGNIVPLVSWIREDGKPI-----SSD-----VKLLGETNLLVPQAQPPHA- 257

Query: 368 NTIVCSAVNYAGSSFVRGKLTVTSD-DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
              VC A         R  +T T+       PIIT  P   T      A F C A   PE
Sbjct: 258 GVYVCRA----NKPHTRHFITATAQLHILVHPIITQPPETITRARAGTARFVCRAEGEPE 313

Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
           P I W   G+ L+ N R  +   G+LV+  L   D G Y C+A +  G    +  L V  
Sbjct: 314 PTIHWLKNGQPLLSNGRVRIQPRGSLVITQLALEDVGYYQCLAENSVGSACATAKLYVTV 373

Query: 487 PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRE 546
                           LPGPP       V+  SVT+ W Q        ++G+ +      
Sbjct: 374 Q-------------DGLPGPPQAVKAVTVSSRSVTVGWEQPES-NWERVIGFSLHY---- 415

Query: 547 TLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600
           T +G +     +     A     T   V+ L PG  Y F V   +  G S  SP
Sbjct: 416 TKTGGSDNMEYQ----FAVNNDTTELYVRDLEPGTKYTFYVVAYSQQGASSASP 465



 Score =  121 bits (292), Expect = 1e-25
 Identities = 112/399 (28%), Positives = 177/399 (44%), Gaps = 30/399 (7%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P   +QP   TV  +  A   C   G P P + W K    V +++    LP G L     
Sbjct: 94  PSFHQQPESQTVMLNSMARFECGFSGFPPPEVTWQKDQAPVPAESRFLTLPTGVL----Q 149

Query: 72  THGRVHSDAGVYWCEATNSYGTARSRNATLHVA------VLREEFRLE--PESKQSAQGD 123
             G    D G Y C ATN   ++ S  A L V        L EE  +   P++    +G 
Sbjct: 150 ISGVQEKDEGFYRCMATNILNSSYSSEAHLSVEQDASVYTLAEELTITRAPQNITVEEGH 209

Query: 124 TVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
           + ++EC+  +G+  P V W +++G+ +  D    + L+   NL++  A+   AG Y C A
Sbjct: 210 SAIMECMA-KGNIVPLVSWIREDGKPISSD----VKLLGETNLLVPQAQPPHAGVYVCRA 264

Query: 183 RNAAGTRESAIATLKIHI--KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
            N   TR    AT ++HI   P +   PE +      +  F CR  G+P P + W ++ G
Sbjct: 265 -NKPHTRHFITATAQLHILVHPIITQPPETITRARAGTARFVCRAEGEPEPTIHWLKN-G 322

Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASG--YLTVYDP-PSINL 297
              +  GRV++   GSL +  + L D G Y C AENSVG+  A+   Y+TV D  P    
Sbjct: 323 QPLLSNGRVRIQPRGSLVITQLALEDVGYYQCLAENSVGSACATAKLYVTVQDGLPGPPQ 382

Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
           +  +V V S +V           E  + +S+   +T    G S +  +  AV +  T L 
Sbjct: 383 AVKAVTVSSRSVTVGWEQPESNWERVIGFSLHYTKT----GGSDNMEYQFAVNNDTTELY 438

Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP 396
           + D +   ++ T    A +  G+S     + + + D+ P
Sbjct: 439 VRDLEPG-TKYTFYVVAYSQQGASSASPPVVIKTLDEVP 476



 Score =  121 bits (291), Expect = 1e-25
 Identities = 124/466 (26%), Positives = 191/466 (40%), Gaps = 40/466 (8%)

Query: 27  QPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85
           Q A L+C  G    P  + W K GV + SD    +L  G L   +     +    G Y C
Sbjct: 16  QEAILHCEVGSREVPYNVTWKKDGVQLNSDEALRVLRNGSLLISQMERDNIE---GRYSC 72

Query: 86  EATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
            A +S G    R+ T+ +A L   F  +PES+          EC    G P P V W+K+
Sbjct: 73  AAQDSVGIVTGRSHTVRLASL-PSFHQQPESQTVMLNSMARFEC-GFSGFPPPEVTWQKD 130

Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
              +    +SR   +  G L I   ++ D G Y+C+A N   +  S+ A L +     + 
Sbjct: 131 QAPV--PAESRFLTLPTGVLQISGVQEKDEGFYRCMATNILNSSYSSEAHLSVEQDASVY 188

Query: 206 T---------GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR-VKVLDDG 255
           T          P+++  + G S   +C   G+ +P V W R  G    P+   VK+L + 
Sbjct: 189 TLAEELTITRAPQNITVEEGHSAIMECMAKGNIVPLVSWIREDG---KPISSDVKLLGET 245

Query: 256 SLRLDNVILADEGEYSCEAE--NSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313
           +L +        G Y C A   ++   ++A+  L +   P I   P ++       ARF 
Sbjct: 246 NLLVPQAQPPHAGVYVCRANKPHTRHFITATAQLHILVHPIITQPPETITRARAGTARFV 305

Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
           C A G PEPT+ W   G + ++  G  R +   + V   +T L + D           C 
Sbjct: 306 CRAEGEPEPTIHWLKNG-QPLLSNGRVRIQPRGSLV---ITQLALEDVGYYQ------CL 355

Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF 433
           A N  GS+    KL VT  D  P P         T+  +S+ V         E +I +  
Sbjct: 356 AENSVGSACATAKLYVTVQDGLPGP--PQAVKAVTVSSRSVTVGWEQPESNWERVIGFSL 413

Query: 434 E----GEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHG 474
                G +    ++  V ND T L ++DL+     T+  VA S+ G
Sbjct: 414 HYTKTGGSDNMEYQFAVNNDTTELYVRDLEPGTKYTFYVVAYSQQG 459



 Score = 82.6 bits (195), Expect = 6e-14
 Identities = 75/236 (31%), Positives = 105/236 (44%), Gaps = 16/236 (6%)

Query: 7   TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGG 65
           T  E   I   P ++TV     A + C A G+  P + W +  G  + SD    +L    
Sbjct: 189 TLAEELTITRAPQNITVEEGHSAIMECMAKGNIVPLVSWIREDGKPISSDV--KLLGETN 246

Query: 66  LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDT 124
           L   +A        AGVY C A N   T     AT  + +L      + PE+   A+  T
Sbjct: 247 LLVPQAQ----PPHAGVYVCRA-NKPHTRHFITATAQLHILVHPIITQPPETITRARAGT 301

Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
               C    G PEP ++W KNGQ LL +G  R+ +   G+LVI      D G YQC+A N
Sbjct: 302 ARFVC-RAEGEPEPTIHWLKNGQPLLSNG--RVRIQPRGSLVITQLALEDVGYYQCLAEN 358

Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
           + G+   A A L + ++  L   P+ V A T SS +    VG +  P+  W R  G
Sbjct: 359 SVGS-ACATAKLYVTVQDGLPGPPQAVKAVTVSSRS--VTVGWEQ-PESNWERVIG 410



 Score = 71.7 bits (168), Expect = 1e-10
 Identities = 72/294 (24%), Positives = 119/294 (40%), Gaps = 20/294 (6%)

Query: 207 GPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA 265
           G    V          C VG   +P +V W++     N     ++VL +GSL +  +   
Sbjct: 6   GQTHTVLLPDQEAILHCEVGSREVPYNVTWKKDGVQLNSDEA-LRVLRNGSLLISQMERD 64

Query: 266 D-EGEYSCEAENSVGAVSASGY-LTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPT 323
           + EG YSC A++SVG V+   + + +   PS +  P S  V   ++ARF C  +G P P 
Sbjct: 65  NIEGRYSCAAQDSVGIVTGRSHTVRLASLPSFHQQPESQTVMLNSMARFECGFSGFPPPE 124

Query: 324 MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383
           + W  +       P  SR     T V     +  + + D+   R    C A N   SS+ 
Sbjct: 125 VTWQKDQAPV---PAESRFLTLPTGVLQ---ISGVQEKDEGFYR----CMATNILNSSYS 174

Query: 384 -RGKLTVTSDDD----RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438
               L+V  D           IT  P N T+     A+  C A     P+++W  E    
Sbjct: 175 SEAHLSVEQDASVYTLAEELTITRAPQNITVEEGHSAIMECMAKGNIVPLVSWIREDGKP 234

Query: 439 IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
           I +  + +  +  L++       +G Y C A+  H ++  +    +   ++P I
Sbjct: 235 ISSDVK-LLGETNLLVPQAQPPHAGVYVCRANKPHTRHFITATAQLHILVHPII 287



 Score = 56.8 bits (131), Expect = 3e-06
 Identities = 45/169 (26%), Positives = 72/169 (42%), Gaps = 6/169 (3%)

Query: 685 HSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILN 744
           H++      +  L+ YTKYEF +       +G  S+     TL D P  PP ++ +  L+
Sbjct: 748 HTSASEEILVAGLKPYTKYEFQVRSNGVFVDGPYSDIVEKMTLPDRPSSPPADLVLQPLS 807

Query: 745 TTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGV 804
             +V L W PP     NGII  Y +++   +      M    T      S  +  L SG 
Sbjct: 808 QFSVQLHWRPP--VESNGIIAQY-LIMYTTNSSHPDEMWTFLTREGNIFSTEVQGLQSGA 864

Query: 805 SYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAG 853
            Y  ++ A+T+ G GP++  +       +   D+L    MN    I+ G
Sbjct: 865 KYYFKMGAKTVSGWGPYTSALVVETLPPTPSADVLD---MNSVTGIIVG 910



 Score = 53.6 bits (123), Expect = 3e-05
 Identities = 39/186 (20%), Positives = 86/186 (46%), Gaps = 11/186 (5%)

Query: 637 ELIEATPIDSKTIKLMWEI--LNFYYLEGLFIYFRPLDNI-TIEYEMKTILHSNDVSGFE 693
           + ++A  + S+++ + WE    N+  + G  +++        +EY+      +ND +   
Sbjct: 382 QAVKAVTVSSRSVTVGWEQPESNWERVIGFSLHYTKTGGSDNMEYQFAV---NNDTTELY 438

Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
           +  L   TKY F+++ + ++     S   V +TLD+VP   P ++ +   + + +H+ W 
Sbjct: 439 VRDLEPGTKYTFYVVAYSQQGASSASPPVVIKTLDEVPAAAP-SLNLHNHSPSQLHVSWQ 497

Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAE 813
           P   +L NG I  Y +         +    ++    ++  +++M    + + Y V+I+A 
Sbjct: 498 PLLPELSNGQIIKYRIEYG---TQKDDDFSSVEVLGNETQAILMPVQLNSL-YKVRISAS 553

Query: 814 TIIGLG 819
           T  G G
Sbjct: 554 TAAGYG 559


>UniRef50_Q4SI43 Cluster: Chromosome 5 SCAF14581, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 5
           SCAF14581, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 782

 Score =  123 bits (296), Expect = 3e-26
 Identities = 133/512 (25%), Positives = 212/512 (41%), Gaps = 55/512 (10%)

Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
           F ++PES  + +      +C    G PEP + W+K+ + +    D R  L+  G L I  
Sbjct: 55  FHVQPESVHAEESGVARFQC-QIHGLPEPVISWEKDSRPV-DTSDERYTLLPTGVLQITG 112

Query: 170 ARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP 229
            R  D+GR+ C+A N+AG + SA A LK+   PY      +       SV+ Q  V    
Sbjct: 113 LRLEDSGRFCCVAHNSAGVKHSAEAVLKVS-GPYSSALAHNKFIM--KSVSQQAFVLPQM 169

Query: 230 LPDVLWRRSAGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSAS--- 284
              V++R+ +    G + +  ++ +    L     I       SC   +   A+  S   
Sbjct: 170 YSSVIFRQYSQDFPGLLFIRLIREIQHIELMYSRGIQCKGSHPSCSFSSHAPALLLSFLP 229

Query: 285 ---GYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341
                 +VY  P I + P ++ +     A   C ATG P P + WS    R I   G+  
Sbjct: 230 PSGSQSSVYKEPMILVGPENLTLTVHQTAILECVATGYPRPIVSWSRLDGRPIGVEGIQ- 288

Query: 342 DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR---GKLTVTSDDDRPPP 398
                     G   L I+D     S    VC+A N  G+   R   G+L V     + P 
Sbjct: 289 --------VLGTGNLMISDVGVQHS-GVYVCAA-NKPGTRVRRTAQGRLVV-----QAPA 333

Query: 399 IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDL 457
                P + + P+ + A+F C A   PEP + W   G+ L    H +   N+ TL +  +
Sbjct: 334 EFVQPPQSISRPVGTTAIFTCQARGEPEPQLTWLKNGQVLEPGGHVKLRNNNSTLTIYGI 393

Query: 458 DKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTD 517
            + D   Y C+A +  G    S  L V             AD   LPG PT      ++ 
Sbjct: 394 SQDDEAIYQCIAENSAGSTQASARLTV-----------LWAD--GLPGVPTGVQAEALSP 440

Query: 518 TSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSL 577
           T++ +SW + ++  +  I+GY + +  R T    + P        +++   Q  +V++ L
Sbjct: 441 TTIQVSWKEPDQ-NTQEIIGYVLHI--RRT----SDPVEEEYEEAVSKVTLQ--HVIRDL 491

Query: 578 IPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
            P  +Y F V+   SHG S PS  +   T G+
Sbjct: 492 EPSTSYTFYVKAYTSHGASKPSESTTESTPGE 523



 Score = 87.4 bits (207), Expect = 2e-15
 Identities = 72/212 (33%), Positives = 93/212 (43%), Gaps = 9/212 (4%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P I+  P ++T+  HQ A L C A G P P + W +     +      +L  G L    +
Sbjct: 241 PMILVGPENLTLTVHQTAILECVATGYPRPIVSWSRLDGRPIGVEGIQVLGTGNLMI--S 298

Query: 72  THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECL 130
             G  HS  GVY C A N  GT   R A   + V    EF   P+S     G T +  C 
Sbjct: 299 DVGVQHS--GVYVC-AANKPGTRVRRTAQGRLVVQAPAEFVQPPQSISRPVGTTAIFTC- 354

Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
             RG PEP + W KNGQ L   G  ++   +   L I    Q D   YQCIA N+AG+ +
Sbjct: 355 QARGEPEPQLTWLKNGQVLEPGGHVKLR-NNNSTLTIYGISQDDEAIYQCIAENSAGSTQ 413

Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQ 222
            A A L +     L   P  V A+  S  T Q
Sbjct: 414 -ASARLTVLWADGLPGVPTGVQAEALSPTTIQ 444



 Score = 83.4 bits (197), Expect = 3e-14
 Identities = 101/406 (24%), Positives = 159/406 (39%), Gaps = 48/406 (11%)

Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG--RVKVLDDG 255
           ++ +P ++ GPE++      +   +C   G P P V W R  G    P+G   ++VL  G
Sbjct: 237 VYKEPMILVGPENLTLTVHQTAILECVATGYPRPIVSWSRLDG---RPIGVEGIQVLGTG 293

Query: 256 SLRLDNVILADEGEYSCEAENSVGAV--SASGYLTVYDPPSINLSPNSVNVESGNVARFT 313
           +L + +V +   G Y C A      V  +A G L V  P      P S++   G  A FT
Sbjct: 294 NLMISDVGVQHSGVYVCAANKPGTRVRRTAQGRLVVQAPAEFVQPPQSISRPVGTTAIFT 353

Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
           C A G PEP + W   G   ++ PG          + +  + LTI    ++D      C 
Sbjct: 354 CQARGEPEPQLTWLKNGQ--VLEPGGH------VKLRNNNSTLTIYGISQDDEA-IYQCI 404

Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF 433
           A N AGS+    +LTV   D  P   +  G   + L   ++ V         + II +  
Sbjct: 405 AENSAGSTQASARLTVLWADGLPG--VPTGVQAEALSPTTIQVSWKEPDQNTQEIIGYVL 462

Query: 434 EGEAL---IQNHRRNVTNDGTL--VLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPI 488
                   ++       +  TL  V++DL+ S S T+   A + HG    S +    +P 
Sbjct: 463 HIRRTSDPVEEEYEEAVSKVTLQHVIRDLEPSTSYTFYVKAYTSHGASKPSESTTESTP- 521

Query: 489 NPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETL 548
                         +P PPT   T  V  + +   W  ++K+G     GY      R   
Sbjct: 522 ------------GEVPAPPTLH-TKVVNSSVIQAWWEPSSKMGQHQ--GY------RLYY 560

Query: 549 SGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHG 594
            G   P  + G +++     Q  Y +  L P + Y   +   N HG
Sbjct: 561 KGAQAPLFA-GPIILPPNASQ--YTITQLDPSLVYEIKLLAYNQHG 603



 Score = 41.5 bits (93), Expect = 0.14
 Identities = 31/89 (34%), Positives = 39/89 (43%), Gaps = 5/89 (5%)

Query: 17  QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGR 75
           QP  V       A   C+  G P P I W K    V  SD   ++LP G    L+ T  R
Sbjct: 58  QPESVHAEESGVARFQCQIHGLPEPVISWEKDSRPVDTSDERYTLLPTG---VLQITGLR 114

Query: 76  VHSDAGVYWCEATNSYGTARSRNATLHVA 104
           +  D+G + C A NS G   S  A L V+
Sbjct: 115 L-EDSGRFCCVAHNSAGVKHSAEAVLKVS 142



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 40/189 (21%), Positives = 74/189 (39%), Gaps = 14/189 (7%)

Query: 639 IEATPIDSKTIKLMWEI--LNFYYLEGLFIYFRPL-DNITIEYEMKTILHSNDVSGFEIT 695
           ++A  +   TI++ W+    N   + G  ++ R   D +  EYE      S       I 
Sbjct: 433 VQAEALSPTTIQVSWKEPDQNTQEIIGYVLHIRRTSDPVEEEYEEAV---SKVTLQHVIR 489

Query: 696 SLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPP 755
            L   T Y F++  +      KPS S    T  +VP  P ++ +  ++N++ +   W P 
Sbjct: 490 DLEPSTSYTFYVKAYTSHGASKPSESTTESTPGEVPAPPTLHTK--VVNSSVIQAWWEPS 547

Query: 756 ELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETI 815
               Q+    GY +       P     + +     Q T   +T L   + Y +++ A   
Sbjct: 548 SKMGQH---QGYRLYYKGAQAPLFAGPIILPPNASQYT---ITQLDPSLVYEIKLLAYNQ 601

Query: 816 IGLGPFSQK 824
            G G  +++
Sbjct: 602 HGDGNATER 610



 Score = 37.5 bits (83), Expect = 2.2
 Identities = 15/33 (45%), Positives = 19/33 (57%)

Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326
           S ++ P SV+ E   VARF C   G PEP + W
Sbjct: 54  SFHVQPESVHAEESGVARFQCQIHGLPEPVISW 86


>UniRef50_UPI0000ECA0F8 Cluster: Neurofascin precursor.; n=3; Gallus
           gallus|Rep: Neurofascin precursor. - Gallus gallus
          Length = 1249

 Score =  122 bits (295), Expect = 5e-26
 Identities = 95/288 (32%), Positives = 144/288 (50%), Gaps = 15/288 (5%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGLFFL 69
           APY +++P ++ +A  +   L CRA G+P P+I+W   G  +  S  + S   AG     
Sbjct: 352 APYWLDEPQNLILAPGEDGRLVCRANGNPKPSIQWLVNGEPIEGSPPNPSREVAGDTIVF 411

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTVVL 127
           R T  ++ S A VY C A+N +G   + NA + V  +     L P ++  +  Q +   L
Sbjct: 412 RDT--QIGSSA-VYQCNASNEHGYLLA-NAFVSVLDVPPRI-LAPRNQLIKVIQYNRTRL 466

Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDS-RMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
           +C P  GSP P + W KNGQ  + DG + + H  + G+L +  AR+ D G Y C+A N  
Sbjct: 467 DC-PFFGSPIPTLRWFKNGQGNMLDGGNYKAH--ENGSLEMSMARKEDQGIYTCVATNIL 523

Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
           G  E+ +  L++     ++ GPED V + GS     CRV  DP   +          + +
Sbjct: 524 GKVEAQV-RLEVKDPTRIVRGPEDQVVKRGSMPRLHCRVKHDPTLKLTVTWLKDDAPLYI 582

Query: 247 G-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
           G R+K  DDG L +  V   D+G+Y+C A   +   SA  YLTV   P
Sbjct: 583 GNRMKKEDDG-LTIYGVAEKDQGDYTCVASTELDKDSAKAYLTVLALP 629



 Score =  120 bits (290), Expect = 2e-25
 Identities = 132/522 (25%), Positives = 210/522 (40%), Gaps = 44/522 (8%)

Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175
           S+   +G  ++LEC+   G P P++ W K G  L   G +++   +   L I +  + D+
Sbjct: 271 SQMVLRGVDLLLECIAS-GVPAPDIMWYKKGGELPA-GKTKLENFNKA-LRISNVSEEDS 327

Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
           G Y C+A N  G+    I+ +++   PY +  P++++   G      CR  G+P P + W
Sbjct: 328 GEYFCLASNKMGSIRHTIS-VRVKAAPYWLDEPQNLILAPGEDGRLVCRANGNPKPSIQW 386

Query: 236 RRSAGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
             +     G+ P    +V  D  +  D  I      Y C A N  G + A+ +++V D P
Sbjct: 387 LVNGEPIEGSPPNPSREVAGDTIVFRDTQI-GSSAVYQCNASNEHGYLLANAFVSVLDVP 445

Query: 294 SINLSPNS--VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
              L+P +  + V   N  R  C   G P PT+ W   G   ++  G    K H      
Sbjct: 446 PRILAPRNQLIKVIQYNRTRLDCPFFGSPIPTLRWFKNGQGNMLDGG--NYKAHENGS-- 501

Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
               L ++   K D +    C A N  G    + +L V     + P  I  GP +Q +  
Sbjct: 502 ----LEMSMARKED-QGIYTCVATNILGKVEAQVRLEV-----KDPTRIVRGPEDQVVKR 551

Query: 412 KSMAVFPCTAICTP--EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
            SM    C     P  +  + W  +   L   +R    +DG L +  + + D G YTCVA
Sbjct: 552 GSMPRLHCRVKHDPTLKLTVTWLKDDAPLYIGNRMKKEDDG-LTIYGVAEKDQGDYTCVA 610

Query: 470 SSRHGKYVWSGALLVDS-PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNN 528
           S+   K      L V + PI P       A+    P  P      ++ + SV L+W   +
Sbjct: 611 STELDKDSAKAYLTVLALPITP-------AEKPERPDRPRDLELSDLAERSVKLTWIPGD 663

Query: 529 KIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVR 588
              +S I  Y V+ F  +             W   +R     +  + SL P + Y F V 
Sbjct: 664 D-NNSPITDYIVQ-FEEDRFQPGT-------WHNHSRYPGNVNSALLSLSPYVNYQFRVI 714

Query: 589 TENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNI 630
             N  G S PS  S+          +   TGV  +   +NN+
Sbjct: 715 AVNDVGSSLPSMPSERYQTSGARPEI-NPTGVQGAGTQKNNM 755



 Score =  112 bits (270), Expect = 5e-23
 Identities = 94/348 (27%), Positives = 149/348 (42%), Gaps = 21/348 (6%)

Query: 23  VARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAG 81
           V R     L C A G P+P I WYK GG L    T            LR ++     D+G
Sbjct: 274 VLRGVDLLLECIASGVPAPDIMWYKKGGELPAGKTKLENFNKA----LRISNVS-EEDSG 328

Query: 82  VYWCEATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNV 140
            Y+C A+N  G+ R    T+ V V    + L EP++   A G+   L C    G+P+P++
Sbjct: 329 EYFCLASNKMGSIRH---TISVRVKAAPYWLDEPQNLILAPGEDGRLVCRA-NGNPKPSI 384

Query: 141 YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
            W  NG+ +     +    V G  +V +D +   +  YQC A N  G   +      + +
Sbjct: 385 QWLVNGEPIEGSPPNPSREVAGDTIVFRDTQIGSSAVYQCNASNEHGYLLANAFVSVLDV 444

Query: 201 KPYLITGPEDVVAQTGSSVT-FQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL 259
            P ++     ++     + T   C   G P+P + W ++  G  +  G  K  ++GSL +
Sbjct: 445 PPRILAPRNQLIKVIQYNRTRLDCPFFGSPIPTLRWFKNGQGNMLDGGNYKAHENGSLEM 504

Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGR 319
                 D+G Y+C A N +G V A   L V DP  I   P    V+ G++ R  C     
Sbjct: 505 SMARKEDQGIYTCVATNILGKVEAQVRLEVKDPTRIVRGPEDQVVKRGSMPRLHCRVKHD 564

Query: 320 P--EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
           P  + T+ W  +     I   M ++        DG+T+  + + D+ D
Sbjct: 565 PTLKLTVTWLKDDAPLYIGNRMKKED-------DGLTIYGVAEKDQGD 605



 Score = 61.3 bits (142), Expect = 2e-07
 Identities = 50/160 (31%), Positives = 72/160 (45%), Gaps = 9/160 (5%)

Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQ---DARQTD-AGR 177
           D + +EC   +G+P P   W +NG+      D ++ +    G LVI      R  D  G 
Sbjct: 56  DNIFIEC-EAKGNPVPTFSWTRNGKFFNVAKDPKVSMRRRSGTLVIDFHGGGRPDDYEGE 114

Query: 178 YQCIARNAAGTRESAIATLKIHIKPYLITGPEDVV-AQTGSSVTFQCR-VGGDPLPDVLW 235
           YQC ARN  GT  S+   L++   P       DV+    G+ ++ QC    G P P + W
Sbjct: 115 YQCFARNDYGTALSSKIHLQVSRSPLWPKEKVDVIEVDEGAPLSLQCNPPPGLPPPVIFW 174

Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILAD-EGEYSCEA 274
             S+        RV    +G L   NV+L D + +YSC A
Sbjct: 175 MSSSMEPIHQDKRVSQGQNGDLYFSNVMLQDAQTDYSCNA 214



 Score = 60.9 bits (141), Expect = 2e-07
 Identities = 53/183 (28%), Positives = 75/183 (40%), Gaps = 14/183 (7%)

Query: 10  EAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGL 66
           + P I +Q + D  V       + C A G+P P   W + G    V  D   S+    G 
Sbjct: 38  QPPTITKQSVKDYIVDPRDNIFIECEAKGNPVPTFSWTRNGKFFNVAKDPKVSMRRRSGT 97

Query: 67  FFLRATHGRVHSD-AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA----Q 121
             +    G    D  G Y C A N YGTA S  + +H+ V R    L P+ K       +
Sbjct: 98  LVIDFHGGGRPDDYEGEYQCFARNDYGTALS--SKIHLQVSRSP--LWPKEKVDVIEVDE 153

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQC 180
           G  + L+C PP G P P ++W  +    +   D R+     G+L   +    DA   Y C
Sbjct: 154 GAPLSLQCNPPPGLPPPVIFWMSSSMEPIHQ-DKRVSQGQNGDLYFSNVMLQDAQTDYSC 212

Query: 181 IAR 183
            AR
Sbjct: 213 NAR 215



 Score = 52.0 bits (119), Expect = 1e-04
 Identities = 66/292 (22%), Positives = 115/292 (39%), Gaps = 26/292 (8%)

Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLD-DGSLRLD--NVIL 264
           +D +     ++  +C   G+P+P   W R+    N+    +V +    G+L +D      
Sbjct: 48  KDYIVDPRDNIFIECEAKGNPVPTFSWTRNGKFFNVAKDPKVSMRRRSGTLVIDFHGGGR 107

Query: 265 AD--EGEYSCEAENSVG-AVSASGYLTVYDPPSINLSP-NSVNVESGNVARFTCTAT-GR 319
            D  EGEY C A N  G A+S+  +L V   P       + + V+ G      C    G 
Sbjct: 108 PDDYEGEYQCFARNDYGTALSSKIHLQVSRSPLWPKEKVDVIEVDEGAPLSLQCNPPPGL 167

Query: 320 PEPTMFWSVEGNRTI-----IFPGMSRDKYHATAVF-DGVTVLTIN------DTDKNDSR 367
           P P +FW       I     +  G + D Y +  +  D  T  + N       T +  + 
Sbjct: 168 PPPVIFWMSSSMEPIHQDKRVSQGQNGDLYFSNVMLQDAQTDYSCNARFHFTHTIQQKNP 227

Query: 368 NTIVCSAVNYAGSSFVRGKLTVTS----DDDRPPPIITNGPSNQTLPIKSM-AVFPCTAI 422
            T+          + +R    + S     +  P  +   G S+  + ++ +  +  C A 
Sbjct: 228 YTLKVKTKKPHNETSLRNHTDMYSARGVTETTPSFMYPYGTSSSQMVLRGVDLLLECIAS 287

Query: 423 CTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
             P P I WY +G  L     +    +  L + ++ + DSG Y C+AS++ G
Sbjct: 288 GVPAPDIMWYKKGGELPAGKTKLENFNKALRISNVSEEDSGEYFCLASNKMG 339



 Score = 37.1 bits (82), Expect = 2.9
 Identities = 29/134 (21%), Positives = 61/134 (45%), Gaps = 11/134 (8%)

Query: 644 IDSKTIKLMWEILNFYYLEGLFIYFRP--------LDNITIEYEMKTILHSNDVSGFEIT 695
           ++S  I L W  ++   ++G    +R         L N+ +  + + +    D +   ++
Sbjct: 848 LNSTAIALTWTRVHLDTIQGQLKEYRAYFWRDSSLLKNLWVSKKRQYVSFPGDRNRGIVS 907

Query: 696 SLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPP 755
            L  Y+ Y+  ++    + +G  S  +   T + VP  P   + +   N  +++L+W  P
Sbjct: 908 RLFPYSNYKLEMVVTNGRGDGPRSEVKEFPTPEGVPSSPRY-LRIRQPNLESINLEWDHP 966

Query: 756 ELQLQNGIITGYNV 769
           E    NG++TGYN+
Sbjct: 967 EHP--NGVLTGYNL 978


>UniRef50_Q59FX6 Cluster: Protein tyrosine phosphatase, receptor
           type, sigma isoform 3 variant; n=14; Amniota|Rep:
           Protein tyrosine phosphatase, receptor type, sigma
           isoform 3 variant - Homo sapiens (Human)
          Length = 1560

 Score =  122 bits (294), Expect = 6e-26
 Identities = 158/612 (25%), Positives = 238/612 (38%), Gaps = 67/612 (10%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI-LPAGGLFF 68
           E P  I++P D        A+  C+A G P P + W K G  V S    +I         
Sbjct: 57  EPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAV 116

Query: 69  LRATHGRVHSDAGVYWCEATNSYG--TARSRNATLHVAVLREEFR---LEPESKQSAQGD 123
           LR    R   D  VY C A NS G  T  ++   L    L   F    + P+ K   +  
Sbjct: 117 LRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTR 176

Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
           T  + C    G+P+P + W K+   +     + R+  +  G L I+ + +TD G+Y+C+A
Sbjct: 177 TATMLCAAS-GNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVA 235

Query: 183 RNAAGTRESAIATLKIHIK---PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
            N+AG R S+ A L + ++   P     P       G +V   C   G P+P V W + A
Sbjct: 236 TNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGA 295

Query: 240 GG----GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295
                  +MP+GR        L L +V   D   Y+C A +S+G + A   +TV   P  
Sbjct: 296 EDLTPEDDMPVGR------NVLELTDV--KDSANYTCVAMSSLGVIEAVAQITVKSLPK- 346

Query: 296 NLSPNSVNVESGNVARFTCT-ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
             +P +  V        T T  +G P+P  ++ +E      +   S+D  +        T
Sbjct: 347 --APGTPMVTENTATSITITWDSGNPDPVSYYVIE------YKSKSQDGPYQIKEDITTT 398

Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
             +I     N S   I  SAVN  G      +  VT   ++ P         + L   +M
Sbjct: 399 RYSIGGLSPN-SEYEIWVSAVNSIGQG-PPSESVVTRTGEQAPASAPRNVQARMLSATTM 456

Query: 415 AVFPCTAICTPEPIIAWY-----FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
            V        P  +I  Y      E E  + N +++  +D  L        D  TYT   
Sbjct: 457 IV-QWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDE-TYTV-- 512

Query: 470 SSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
                  V +   + D P++  I   +      +PG P        ++TS+TLSWS   +
Sbjct: 513 ------RVLAFTSVGDGPLSDPI---QVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQ 563

Query: 530 IGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRT 589
               SI+ Y  E+  RE   G    R              T YVV+ L P   Y F +  
Sbjct: 564 ---ESIIKY--ELLFREGDHGREVGRTFD---------PTTSYVVEDLKPNTEYAFRLAA 609

Query: 590 ENSHGLSGPSPV 601
            +  GL   +PV
Sbjct: 610 RSPQGLGAFTPV 621



 Score =  103 bits (247), Expect = 3e-20
 Identities = 161/670 (24%), Positives = 255/670 (38%), Gaps = 90/670 (13%)

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LR 258
           P  I  P+D +  +G   +F C+  GDP P V W +     N         D+ +   LR
Sbjct: 59  PRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLR 118

Query: 259 LDNVILA-DEGEYSCEAENSVGAVSASGYLTVYDP-------PSINLSPNSVNVESGNVA 310
           +  +    DE  Y C A+NSVG ++    LTV          P+I++ P    VE    A
Sbjct: 119 IQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTA 178

Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
              C A+G P+P + W  +     + P  S  +        G   L I  +++ D +   
Sbjct: 179 TMLCAASGNPDPEITWFKDF--LPVDPSASNGRIKQLR--SGA--LQIESSEETD-QGKY 231

Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA 430
            C A N AG  +              P       S++ +P  ++ +  C A+ +P P + 
Sbjct: 232 ECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMPGGNVNI-TCVAVGSPMPYVK 290

Query: 431 WYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
           W    E L       V   G  VL+  D  DS  YTCVA S  G                
Sbjct: 291 WMQGAEDLTPEDDMPV---GRNVLELTDVKDSANYTCVAMSSLGV--------------- 332

Query: 491 NIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSG 550
            I       V SLP  P  P+    T TS+T++W   N      +  Y +E  S+     
Sbjct: 333 -IEAVAQITVKSLPKAPGTPMVTENTATSITITWDSGNP---DPVSYYVIEYKSK----- 383

Query: 551 NNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDD 610
                +  G   I   +  T Y +  L P   Y   V   NS G  GP   S     G+ 
Sbjct: 384 -----SQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIG-QGPPSESVVTRTGEQ 437

Query: 611 SNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRP 670
           + +         + + R    T  IV+  E  P++   +   + +  +Y +E       P
Sbjct: 438 APA-----SAPRNVQARMLSATTMIVQWEE--PVEPNGLIRGYRV--YYTMEPE----HP 484

Query: 671 LDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDV 730
           + N    ++   +   +D     + SL +   Y   ++ F    +G  S+    +T   V
Sbjct: 485 VGN----WQKHNV---DDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGV 537

Query: 731 PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH 790
           P G P+N+     + T++ L WSPP    Q  II  Y ++    D         +  T  
Sbjct: 538 P-GQPMNLRAEARSETSITLSWSPPR---QESIIK-YELLFREGDHGRE-----VGRTFD 587

Query: 791 QATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSI 850
             TS ++ +L     Y+ ++AA +  GLG F+  V      R   L  +S  P N +V +
Sbjct: 588 PTTSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVV------RQRTLQSIS--PKNFKVKM 639

Query: 851 VAGDFVMETW 860
           +    V+ +W
Sbjct: 640 IMKTSVLLSW 649


>UniRef50_Q4RVZ3 Cluster: Chromosome 9 SCAF14991, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 9 SCAF14991, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 882

 Score =  122 bits (293), Expect = 8e-26
 Identities = 103/329 (31%), Positives = 142/329 (43%), Gaps = 24/329 (7%)

Query: 25  RHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVY 83
           R Q   L C   G P+P + W +  G +  S T + +     L+F   +     SD G Y
Sbjct: 17  RGQTLELECIVQGLPTPKVSWLRRDGEMSESRTSKEMFDRR-LYFNNISE----SDGGEY 71

Query: 84  WCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSPEPNVYW 142
            C A NS G       T  V V    + +  P S+  A G+TV L+C    G P P + W
Sbjct: 72  QCIAENSQGKIVH---TYTVTVEASPYWINAPASQLYAPGETVKLDCQAD-GIPPPTITW 127

Query: 143 KKNGQTLLFDG-DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201
             NG  L     + R  L D G+L+++D    D   YQC A N  GT  +      I + 
Sbjct: 128 TVNGVPLSATAVEPRRLLTDSGSLILKDVSFGDTAIYQCQASNKHGTILTNTNVYVIELP 187

Query: 202 PYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLR 258
           P ++T  ED    T   G     +C   G P P V W  S+    +   RV +L +G L 
Sbjct: 188 PQILT--EDGSTYTFVEGQKAVLECETFGSPKPKVTWESSSTSLPLADPRVNLLTNGGLE 245

Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATG 318
           + NV   DEG Y+C  +NS   VS S  L V +   I   P ++ ++ G  A FTC    
Sbjct: 246 VSNVSHDDEGIYTCSIQNS--NVSVSAELEVLNRTVILSPPQALRMQPGKTAIFTCMYIT 303

Query: 319 RPE---PTMFWSVEGNRTIIFPGMSRDKY 344
            P+   P + W    N   IF   S +KY
Sbjct: 304 DPKLHSPVLQW--RKNDQKIFESHSDEKY 330



 Score =  105 bits (252), Expect = 7e-21
 Identities = 82/292 (28%), Positives = 129/292 (44%), Gaps = 18/292 (6%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSDTHRSILP 62
           VT   +PY I  P     A  +   L+C+A G P P I W   GV       +  R +  
Sbjct: 88  VTVEASPYWINAPASQLYAPGETVKLDCQADGIPPPTITWTVNGVPLSATAVEPRRLLTD 147

Query: 63  AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS-AQ 121
           +G L     + G    D  +Y C+A+N +GT  + N  ++V  L  +   E  S  +  +
Sbjct: 148 SGSLILKDVSFG----DTAIYQCQASNKHGTILT-NTNVYVIELPPQILTEDGSTYTFVE 202

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
           G   VLEC    GSP+P V W+ +  +L    D R++L+  G L + +    D G Y C 
Sbjct: 203 GQKAVLEC-ETFGSPKPKVTWESSSTSLPL-ADPRVNLLTNGGLEVSNVSHDDEGIYTCS 260

Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP---LPDVLWRRS 238
            +N   +  S  A L++  +  +++ P+ +  Q G +  F C    DP    P + WR++
Sbjct: 261 IQN---SNVSVSAELEVLNRTVILSPPQALRMQPGKTAIFTCMYITDPKLHSPVLQWRKN 317

Query: 239 AGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
                      K   +G  L + NV   DEG Y+C+    +    AS  LT+
Sbjct: 318 DQKIFESHSDEKYTFEGPDLIISNVEPGDEGVYTCQIITKLDMAEASSNLTL 369



 Score = 94.3 bits (224), Expect = 2e-17
 Identities = 76/265 (28%), Positives = 109/265 (41%), Gaps = 14/265 (5%)

Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV-KVLDDGSLRLDNVI 263
           I G     A  G ++  +C V G P P V W R    G M   R  K + D  L  +N+ 
Sbjct: 7   IGGHSTYHALRGQTLELECIVQGLPTPKVSWLRR--DGEMSESRTSKEMFDRRLYFNNIS 64

Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPT 323
            +D GEY C AENS G +  +  +TV   P    +P S     G   +  C A G P PT
Sbjct: 65  ESDGGEYQCIAENSQGKIVHTYTVTVEASPYWINAPASQLYAPGETVKLDCQADGIPPPT 124

Query: 324 MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383
           + W+V G      P +S        +      L + D    D+     C A N  G+   
Sbjct: 125 ITWTVNG-----VP-LSATAVEPRRLLTDSGSLILKDVSFGDTA-IYQCQASNKHGTILT 177

Query: 384 RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNH 442
              + V    + PP I+T   S  T      AV  C    +P+P + W     +L + + 
Sbjct: 178 NTNVYVI---ELPPQILTEDGSTYTFVEGQKAVLECETFGSPKPKVTWESSSTSLPLADP 234

Query: 443 RRNVTNDGTLVLKDLDKSDSGTYTC 467
           R N+  +G L + ++   D G YTC
Sbjct: 235 RVNLLTNGGLEVSNVSHDDEGIYTC 259



 Score = 62.9 bits (146), Expect = 5e-08
 Identities = 45/180 (25%), Positives = 71/180 (39%), Gaps = 13/180 (7%)

Query: 5   YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPA 63
           YV       + E     T    Q A L C   GSP P + W      L ++D   ++L  
Sbjct: 182 YVIELPPQILTEDGSTYTFVEGQKAVLECETFGSPKPKVTWESSSTSLPLADPRVNLLTN 241

Query: 64  GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
           GGL     +    H D G+Y C   NS  +  +    L+  V+       P++ +   G 
Sbjct: 242 GGLEVSNVS----HDDEGIYTCSIQNSNVSVSAELEVLNRTVILS----PPQALRMQPGK 293

Query: 124 TVVLECL---PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
           T +  C+    P+    P + W+KN Q +        +  +G +L+I +    D G Y C
Sbjct: 294 TAIFTCMYITDPK-LHSPVLQWRKNDQKIFESHSDEKYTFEGPDLIISNVEPGDEGVYTC 352



 Score = 50.8 bits (116), Expect = 2e-04
 Identities = 45/171 (26%), Positives = 65/171 (38%), Gaps = 18/171 (10%)

Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
           G      C   G P P + W       +   G   +   +  +FD    L  N+  ++D 
Sbjct: 18  GQTLELECIVQGLPTPKVSW-------LRRDGEMSESRTSKEMFD--RRLYFNNISESDG 68

Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
                C A N  G       +TV +      P   N P++Q           C A   P 
Sbjct: 69  -GEYQCIAENSQGKIVHTYTVTVEAS-----PYWINAPASQLYAPGETVKLDCQADGIPP 122

Query: 427 PIIAWYFEG---EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
           P I W   G    A     RR +T+ G+L+LKD+   D+  Y C AS++HG
Sbjct: 123 PTITWTVNGVPLSATAVEPRRLLTDSGSLILKDVSFGDTAIYQCQASNKHG 173



 Score = 41.1 bits (92), Expect = 0.18
 Identities = 24/87 (27%), Positives = 40/87 (45%), Gaps = 2/87 (2%)

Query: 733 GPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQA 792
           GPP+++ +   + T + L W+PP+    NGI+ GY +    +    +  M   +    Q 
Sbjct: 589 GPPMSLVLDSPSETEITLHWTPPD--QPNGILIGYELQYQQIMQSDDSPMQVEDKVNPQT 646

Query: 793 TSLIMTNLTSGVSYSVQIAAETIIGLG 819
           TSL++  L     Y   +   T  GLG
Sbjct: 647 TSLMLKGLDRHSHYRFYLMGRTAAGLG 673



 Score = 39.5 bits (88), Expect = 0.55
 Identities = 15/76 (19%), Positives = 40/76 (52%)

Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
           +   + ++ +E  +    ++  G   +  +  + +DVP  PP+++ + + N+TT+ + W+
Sbjct: 462 VNDTQNFSAFEIKVQAVNERGRGPEPDPVIGYSGEDVPLEPPLDVGILMENSTTIKVTWA 521

Query: 754 PPELQLQNGIITGYNV 769
           P + +   G + GY +
Sbjct: 522 PIDKETVRGRLLGYKI 537



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 23/113 (20%), Positives = 53/113 (46%), Gaps = 7/113 (6%)

Query: 495 FRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTP 554
           F + D++ +PGPP   +  + ++T +TL W+  ++  +  ++GY+++   ++ +  +++P
Sbjct: 579 FSSYDIAVIPGPPMSLVLDSPSETEITLHWTPPDQ-PNGILIGYELQY--QQIMQSDDSP 635

Query: 555 RNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
                 V        T  ++K L     Y F +    + GL  P     + T+
Sbjct: 636 MQVEDKV----NPQTTSLMLKGLDRHSHYRFYLMGRTAAGLGEPIKKDGATTL 684


>UniRef50_P13591 Cluster: Neural cell adhesion molecule 1, 140 kDa
           isoform precursor; n=109; Euteleostomi|Rep: Neural cell
           adhesion molecule 1, 140 kDa isoform precursor - Homo
           sapiens (Human)
          Length = 848

 Score =  122 bits (293), Expect = 8e-26
 Identities = 111/429 (25%), Positives = 177/429 (41%), Gaps = 28/429 (6%)

Query: 79  DAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPE 137
           DAG+Y C  T   G+     AT++V + ++  F+  P  ++  +G+  V+ C      P 
Sbjct: 90  DAGIYKCVVTGEDGS--ESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLP- 146

Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
           P + WK  G+ ++   D R  ++    L I+  ++TD G Y+C  R  A   E     ++
Sbjct: 147 PTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILA-RGEINFKDIQ 205

Query: 198 IHIK-PYLITGPEDVV---AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL- 252
           + +  P  I   +++V   A  G SVT  C   G P P + W +            K + 
Sbjct: 206 VIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIF 265

Query: 253 -DDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310
            DD S L +  V   DE EY C AEN  G   A+ +L V+  P I    N   +E     
Sbjct: 266 SDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQV 325

Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
             TC A+G P P++ W     R I     + D +        V+ LT+      D+    
Sbjct: 326 TLTCEASGDPIPSITWRT-STRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDA-GEY 383

Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPI-ITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
           +C+A N  G       L V        P+ +     NQ           C     P   I
Sbjct: 384 ICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQ-------VNITCEVFAYPSATI 436

Query: 430 AWYFEGEALIQNHRRNVTNDGT-----LVLKDLDKSDSGTYTCVASSRHGKYVWSGALL- 483
           +W+ +G+ L  ++  N+    T     L +    ++D G Y C A +R G+      L+ 
Sbjct: 437 SWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQ 496

Query: 484 VDSPINPNI 492
            D+P +P+I
Sbjct: 497 ADTPSSPSI 505



 Score =  101 bits (241), Expect = 2e-19
 Identities = 96/380 (25%), Positives = 147/380 (38%), Gaps = 30/380 (7%)

Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLV----DGGNLVIQ 168
           P   + + G++    C     + + ++ W   NG+ L      R+ +V        L I 
Sbjct: 26  PSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLT-PNQQRISVVWNDDSSSTLTIY 84

Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228
           +A   DAG Y+C+     G+   A   +KI  K      P     + G      C V   
Sbjct: 85  NANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSS 144

Query: 229 PLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAE-NSVGAVSASGY 286
             P ++W+       +    R  VL +  L++  +   DEG Y CE    + G ++    
Sbjct: 145 LPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDI 204

Query: 287 LTVYD-PPSINLSPNSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDK 343
             + + PP+I    N VN  +  G      C A G PEPTM W+ +G +  I      +K
Sbjct: 205 QVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQ--IEQEEDDEK 262

Query: 344 YHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG 403
           Y      D  + LTI   DKND     +C A N AG       L V +      P IT  
Sbjct: 263 Y---IFSDDSSQLTIKKVDKNDEAE-YICIAENKAGEQDATIHLKVFA-----KPKITYV 313

Query: 404 PSNQTLPIKSMAVFPCTAICTPEPIIAW------YFEGEALIQNHR--RNVTNDGTLVLK 455
            +   + ++      C A   P P I W          E  +  H   R+     +L LK
Sbjct: 314 ENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLK 373

Query: 456 DLDKSDSGTYTCVASSRHGK 475
            +  +D+G Y C AS+  G+
Sbjct: 374 SIQYTDAGEYICTASNTIGQ 393



 Score = 71.3 bits (167), Expect = 1e-10
 Identities = 81/303 (26%), Positives = 122/303 (40%), Gaps = 30/303 (9%)

Query: 19  LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGLFFLRATHGRV 76
           ++ T    Q  TL C A G P P + W K G  +    D  + I         + T  +V
Sbjct: 221 VNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDS---SQLTIKKV 277

Query: 77  -HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGS 135
             +D   Y C A N  G    ++AT+H+ V  +      E++ + + +  V       G 
Sbjct: 278 DKNDEAEYICIAENKAG---EQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGD 334

Query: 136 PEPNVYWKKNGQTL-----LFDGDS--RMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
           P P++ W+ + + +       DG    R H     +L ++  + TDAG Y C A N  G 
Sbjct: 335 PIPSITWRTSTRNISSEEKTLDGHMVVRSH-ARVSSLTLKSIQYTDAGEYICTASNTIG- 392

Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP--- 245
           ++S    L++   P L  GP  V    G+ V   C V   P   + W R   G  +P   
Sbjct: 393 QDSQSMYLEVQYAPKL-QGPVAVYTWEGNQVNITCEVFAYPSATISWFRD--GQLLPSSN 449

Query: 246 LGRVKVLDDGSLRLDNVILADE---GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
              +K+ +  S     V    E   G Y+C A N +G  S    L   D PS   SP+  
Sbjct: 450 YSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPS---SPSID 506

Query: 303 NVE 305
            VE
Sbjct: 507 QVE 509


>UniRef50_UPI0000DB6DF8 Cluster: PREDICTED: similar to leucine-rich
           repeats and immunoglobulin-like domains 3; n=1; Apis
           mellifera|Rep: PREDICTED: similar to leucine-rich
           repeats and immunoglobulin-like domains 3 - Apis
           mellifera
          Length = 909

 Score =  121 bits (292), Expect = 1e-25
 Identities = 90/304 (29%), Positives = 130/304 (42%), Gaps = 18/304 (5%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIR--WYKGGVLVVSD--------THRSIL 61
           P IIE+P      +    TL CRA  +    +   W    + +  D        T   + 
Sbjct: 479 PRIIEEPKSQMGIKGDNVTLVCRATSTAIARLHFTWKHDNIEINDDNLQINTDSTENGVT 538

Query: 62  PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
            A  +  L       H++AG Y C  TN+YGT  S  A L + +    F   P   +   
Sbjct: 539 EATSILHLTNV---THANAGKYQCMVTNTYGTTYSAKAKLSILIY-PSFSKIPHDIRVIA 594

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNG-QTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQ 179
           G T  LEC    G P P + W+K+G        + RMH++   + L I D +  D+G Y 
Sbjct: 595 GSTARLEC-SAEGQPSPQIAWQKDGGNDFPAARERRMHMMPTDDVLFIVDVKTADSGVYS 653

Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
           C A+N AG    A ATL I   P  +   E+     G S+  +C   G P P + WR++ 
Sbjct: 654 CTAQNLAGLIV-ANATLTILETPSFVKPMENKEVTVGGSIVLECMASGMPRPKLSWRKNG 712

Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
                        +D  L + +  ++D G Y CE  NS+G+V  + +LTV   P    SP
Sbjct: 713 NPLLATERHFFTAEDQLLIIVDTRISDAGSYECEMSNSLGSVVGASHLTVKPAPISTPSP 772

Query: 300 NSVN 303
            SVN
Sbjct: 773 GSVN 776



 Score =  113 bits (272), Expect = 3e-23
 Identities = 90/306 (29%), Positives = 133/306 (43%), Gaps = 27/306 (8%)

Query: 113 EPESKQSAQGDTVVLECLPPRGS-PEPNVYWKK-----NGQTLLFDGDSRMHLVDGGNLV 166
           EP+S+   +GD V L C     +    +  WK      N   L  + DS  + V     +
Sbjct: 484 EPKSQMGIKGDNVTLVCRATSTAIARLHFTWKHDNIEINDDNLQINTDSTENGVTEATSI 543

Query: 167 IQ--DARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR 224
           +   +    +AG+YQC+  N  GT  SA A L I I P     P D+    GS+   +C 
Sbjct: 544 LHLTNVTHANAGKYQCMVTNTYGTTYSAKAKLSILIYPSFSKIPHDIRVIAGSTARLECS 603

Query: 225 VGGDPLPDVLWRRSAGGGNMPLGRVKVL----DDGSLRLDNVILADEGEYSCEAENSVGA 280
             G P P + W++  GG + P  R + +     D  L + +V  AD G YSC A+N  G 
Sbjct: 604 AEGQPSPQIAWQKD-GGNDFPAARERRMHMMPTDDVLFIVDVKTADSGVYSCTAQNLAGL 662

Query: 281 VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340
           + A+  LT+ + PS      +  V  G      C A+G P P + W   GN     P ++
Sbjct: 663 IVANATLTILETPSFVKPMENKEVTVGGSIVLECMASGMPRPKLSWRKNGN-----PLLA 717

Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII 400
            +++  TA      +L I DT  +D+  +  C   N  GS      LTV     +P PI 
Sbjct: 718 TERHFFTAEDQ---LLIIVDTRISDA-GSYECEMSNSLGSVVGASHLTV-----KPAPIS 768

Query: 401 TNGPSN 406
           T  P +
Sbjct: 769 TPSPGS 774



 Score = 98.3 bits (234), Expect = 1e-18
 Identities = 84/302 (27%), Positives = 126/302 (41%), Gaps = 24/302 (7%)

Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV--LWRRS---AGGGNMPLGRVK----V 251
           KP +I  P+  +   G +VT  CR     +  +   W+         N+ +        V
Sbjct: 478 KPRIIEEPKSQMGIKGDNVTLVCRATSTAIARLHFTWKHDNIEINDDNLQINTDSTENGV 537

Query: 252 LDDGS-LRLDNVILADEGEYSCEAENSVGAV-SASGYLTVYDPPSINLSPNSVNVESGNV 309
            +  S L L NV  A+ G+Y C   N+ G   SA   L++   PS +  P+ + V +G+ 
Sbjct: 538 TEATSILHLTNVTHANAGKYQCMVTNTYGTTYSAKAKLSILIYPSFSKIPHDIRVIAGST 597

Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
           AR  C+A G+P P + W  +G     FP     + H     D   VL I D    DS   
Sbjct: 598 ARLECSAEGQPSPQIAWQKDGGND--FPAARERRMHMMPTDD---VLFIVDVKTADS-GV 651

Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
             C+A N AG       LT+        P+      N+ + +    V  C A   P P +
Sbjct: 652 YSCTAQNLAGLIVANATLTILETPSFVKPM-----ENKEVTVGGSIVLECMASGMPRPKL 706

Query: 430 AWYFEGEALIQNHRRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV-DSP 487
           +W   G  L+   R   T  D  L++ D   SD+G+Y C  S+  G  V +  L V  +P
Sbjct: 707 SWRKNGNPLLATERHFFTAEDQLLIIVDTRISDAGSYECEMSNSLGSVVGASHLTVKPAP 766

Query: 488 IN 489
           I+
Sbjct: 767 IS 768



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 26/84 (30%), Positives = 37/84 (44%), Gaps = 3/84 (3%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
           E P  ++   +  V       L C A G P P + W K G  +++ T R    A     +
Sbjct: 673 ETPSFVKPMENKEVTVGGSIVLECMASGMPRPKLSWRKNGNPLLA-TERHFFTAEDQLLI 731

Query: 70  RATHGRVHSDAGVYWCEATNSYGT 93
                R+ SDAG Y CE +NS G+
Sbjct: 732 -IVDTRI-SDAGSYECEMSNSLGS 753


>UniRef50_UPI00015B6341 Cluster: PREDICTED: similar to KLG; n=1;
           Nasonia vitripennis|Rep: PREDICTED: similar to KLG -
           Nasonia vitripennis
          Length = 1117

 Score =  120 bits (289), Expect = 2e-25
 Identities = 90/279 (32%), Positives = 128/279 (45%), Gaps = 15/279 (5%)

Query: 18  PLDVTVARHQPATLNC--RAGGSPSPAIRWYKGGVLVVSDT---HRSIL-PAGGLFFLRA 71
           P  V+V   +PATL C  RA   P   +RW + G  ++S     +R +  PAG L  +  
Sbjct: 421 PKPVSVMEDEPATLTCSFRAMEPPITQVRWLRDGEALLSKDGVRYRIVEEPAGNLSLIFK 480

Query: 72  THGRVHSDAGVYWCE-ATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
               +  D G Y CE  T  +   RS  A L V   + +F  EP +++     +  + C 
Sbjct: 481 NVQLI--DRGNYVCEIVTKGFSPVRSAPAALSVEE-KLKFSPEPVNRKLELNSSPKISC- 536

Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
             +GS      W KNG    F    R  L   G L      + D G Y C+A N+ G  +
Sbjct: 537 KAQGSTPVTFKWYKNGADS-FPKHVRDEL--NGTLHFNGVLEEDKGNYTCVASNSQGQIK 593

Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250
             I  + + I P     PE+V A  GSSV   C   GDP P + W + +   N+   R +
Sbjct: 594 HTIK-IDVVISPKFTIKPENVTAIEGSSVLLHCAAEGDPKPAIQWDKDSRMNNLNGDRFE 652

Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
           V+ +GSL +  V L+DEG+Y C A NS G     G+L+V
Sbjct: 653 VMANGSLHIKEVYLSDEGKYGCTAGNSAGLKREEGHLSV 691



 Score =  114 bits (275), Expect = 1e-23
 Identities = 128/488 (26%), Positives = 194/488 (39%), Gaps = 46/488 (9%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWY---KGGVLVVSDTHRSILP 62
           V S E   I   P    V R++PA+ +C    + +  ++W+   KG +   SD  RSIL 
Sbjct: 221 VPSNETATIKLVPQKAIVRRYEPASFSCVFDNADN--VQWFFEDKGPI--ESDDERSILD 276

Query: 63  AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVL----REEFRLEPESKQ 118
            G L  L+A         G Y C    +  T +   A L +A L     E F    E + 
Sbjct: 277 NGTLVVLKAEDRH----KGYYACHGLRA-DTVQVYAAELQIAYLYNLTSESFEPPLEDRL 331

Query: 119 SAQGDTVVLE--CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAG 176
           +  G+   L+  CL P G P P ++W++    ++ D    + + D   +V +  R  D G
Sbjct: 332 AVVGENQELQVSCLAPGGLPTPKLFWREPQGRIVSD-TGPVRVQDDTLIVAKARRNADEG 390

Query: 177 RYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC--RVGGDPLPDVL 234
            Y C A N AG  ++ +  + +     L + P+ V        T  C  R    P+  V 
Sbjct: 391 NYTCHAENMAGATQATVRIV-VSWPAELKSSPKPVSVMEDEPATLTCSFRAMEPPITQVR 449

Query: 235 WRRSAGGGNMPLG-RVKVLDD--GSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTV 289
           W R         G R +++++  G+L L   NV L D G Y CE      +   S    +
Sbjct: 450 WLRDGEALLSKDGVRYRIVEEPAGNLSLIFKNVQLIDRGNYVCEIVTKGFSPVRSAPAAL 509

Query: 290 YDPPSINLSPNSVN--VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
                +  SP  VN  +E  +  + +C A G    T  W   G  +  FP   RD+ + T
Sbjct: 510 SVEEKLKFSPEPVNRKLELNSSPKISCKAQGSTPVTFKWYKNGADS--FPKHVRDELNGT 567

Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407
             F+GV           + +    C A N  G      K+ V        P  T  P N 
Sbjct: 568 LHFNGVL---------EEDKGNYTCVASNSQGQIKHTIKIDVVIS-----PKFTIKPENV 613

Query: 408 TLPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYT 466
           T    S  +  C A   P+P I W  +     +   R  V  +G+L +K++  SD G Y 
Sbjct: 614 TAIEGSSVLLHCAAEGDPKPAIQWDKDSRMNNLNGDRFEVMANGSLHIKEVYLSDEGKYG 673

Query: 467 CVASSRHG 474
           C A +  G
Sbjct: 674 CTAGNSAG 681



 Score =  102 bits (244), Expect = 7e-20
 Identities = 100/389 (25%), Positives = 161/389 (41%), Gaps = 28/389 (7%)

Query: 16  EQPLD---VTVARHQPATLNCRA-GGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           E PL+     V  +Q   ++C A GG P+P + W +    +VSDT    +    L   +A
Sbjct: 324 EPPLEDRLAVVGENQELQVSCLAPGGLPTPKLFWREPQGRIVSDTGPVRVQDDTLIVAKA 383

Query: 72  THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVL-REEFRLEPESKQSAQGDTVVLEC- 129
              R ++D G Y C A N  G  +   AT+ + V    E +  P+     + +   L C 
Sbjct: 384 ---RRNADEGNYTCHAENMAGATQ---ATVRIVVSWPAELKSSPKPVSVMEDEPATLTCS 437

Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD--GGNL--VIQDARQTDAGRYQC-IARN 184
                 P   V W ++G+ LL     R  +V+   GNL  + ++ +  D G Y C I   
Sbjct: 438 FRAMEPPITQVRWLRDGEALLSKDGVRYRIVEEPAGNLSLIFKNVQLIDRGNYVCEIVTK 497

Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
                 SA A L +  K      P +   +  SS    C+  G       W ++ G  + 
Sbjct: 498 GFSPVRSAPAALSVEEKLKFSPEPVNRKLELNSSPKISCKAQGSTPVTFKWYKN-GADSF 556

Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
           P   V+   +G+L  + V+  D+G Y+C A NS G +  +  + V   P   + P +V  
Sbjct: 557 PK-HVRDELNGTLHFNGVLEEDKGNYTCVASNSQGQIKHTIKIDVVISPKFTIKPENVTA 615

Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
             G+     C A G P+P + W  +         ++ D++   A  +G   L I +   +
Sbjct: 616 IEGSSVLLHCAAEGDPKPAIQWDKDSRMN----NLNGDRFEVMA--NG--SLHIKEVYLS 667

Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
           D      C+A N AG     G L+V + D
Sbjct: 668 D-EGKYGCTAGNSAGLKREEGHLSVRAGD 695



 Score = 62.5 bits (145), Expect = 7e-08
 Identities = 145/636 (22%), Positives = 239/636 (37%), Gaps = 67/636 (10%)

Query: 13  YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRAT 72
           Y    P D  V   Q  TL C A         W   G  +     R   P  G   +   
Sbjct: 38  YFTVSPSDHQVVEGQSVTLRCEAEPGAPVRYSWKIDGQPLAPSPRRH--PKSGNLLISRV 95

Query: 73  HGRVHSDAGVYWCEATN--SYGTARSRNATLHVAVLRE-EFRLE-PESKQSAQ-GDTVVL 127
           +  +  D+G + C ATN  S  +  S  A + +  + E   +L+ P+   + + G  V L
Sbjct: 96  NRML--DSGSFVCVATNEKSGDSIESSPAKIDIQWISEASVQLQQPKLAPNIRAGGKVEL 153

Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
            C    GS E    W +N +++    + R+ +     L+IQ+A   D G Y+C+ARN AG
Sbjct: 154 RCHVD-GSGELKYEWFRNTKSVA--PNDRVEM-KRNLLLIQEASPEDNGVYRCLARNQAG 209

Query: 188 TRESAIATLKIHIKPYLITG-----PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
              S +A     I P   T      P+  + +     +F C    D   +V W     G 
Sbjct: 210 A--SPLAHSYPLIVPSNETATIKLVPQKAIVRRYEPASFSCVF--DNADNVQWFFEDKGP 265

Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEA--ENSVGAVSASGYLT-VYDPPSINLSP 299
                   +LD+G+L +       +G Y+C     ++V   +A   +  +Y+  S +  P
Sbjct: 266 IESDDERSILDNGTLVVLKAEDRHKGYYACHGLRADTVQVYAAELQIAYLYNLTSESFEP 325

Query: 300 ----NSVNVESGNVARFTCTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
                   V      + +C A  G P P +FW     R +   G  R       V D   
Sbjct: 326 PLEDRLAVVGENQELQVSCLAPGGLPTPKLFWREPQGRIVSDTGPVR-------VQD--D 376

Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
            L +    +N       C A N AG++    ++ V+      P  + + P   ++     
Sbjct: 377 TLIVAKARRNADEGNYTCHAENMAGATQATVRIVVSW-----PAELKSSPKPVSVMEDEP 431

Query: 415 AVFPCTAICTPEPI--IAWYFEGEALIQNH--RRNVTNDG----TLVLKDLDKSDSGTYT 466
           A   C+      PI  + W  +GEAL+     R  +  +     +L+ K++   D G Y 
Sbjct: 432 ATLTCSFRAMEPPITQVRWLRDGEALLSKDGVRYRIVEEPAGNLSLIFKNVQLIDRGNYV 491

Query: 467 CVASSRHGKYVWS--GALLVDSPINPNIH-FFRAADVSSLPGPPTKPITHNVTDTSVTLS 523
           C   ++    V S   AL V+  +  +     R  +++S P    K        T VT  
Sbjct: 492 CEIVTKGFSPVRSAPAALSVEEKLKFSPEPVNRKLELNSSPKISCKA----QGSTPVTFK 547

Query: 524 WSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRG--WVVIARRVHQTHYVVKSLIPGI 581
           W +N   G+ S   + V      TL  N      +G    V +    Q  + +K  +  I
Sbjct: 548 WYKN---GADSFPKH-VRDELNGTLHFNGVLEEDKGNYTCVASNSQGQIKHTIKIDVV-I 602

Query: 582 TYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSL-WE 616
           +  F ++ EN   + G S +      GD   ++ W+
Sbjct: 603 SPKFTIKPENVTAIEGSSVLLHCAAEGDPKPAIQWD 638



 Score = 42.7 bits (96), Expect = 0.059
 Identities = 34/122 (27%), Positives = 51/122 (41%), Gaps = 11/122 (9%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
           +P    +P +VT        L+C A G P PAI+W K   +   +  R  + A G   ++
Sbjct: 603 SPKFTIKPENVTAIEGSSVLLHCAAEGDPKPAIQWDKDSRMNNLNGDRFEVMANGSLHIK 662

Query: 71  ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV-----LREEFRLEPESKQSAQGDTV 125
             +    SD G Y C A NS G  R      H++V      R +  L+     S    TV
Sbjct: 663 EVY---LSDEGKYGCTAGNSAGLKREEG---HLSVRAGDGYRSDMELDAAEDGSMMTKTV 716

Query: 126 VL 127
           ++
Sbjct: 717 II 718


>UniRef50_Q23991 Cluster: Peroxidasin precursor; n=7; Coelomata|Rep:
           Peroxidasin precursor - Drosophila melanogaster (Fruit
           fly)
          Length = 1535

 Score =  120 bits (289), Expect = 2e-25
 Identities = 95/302 (31%), Positives = 140/302 (46%), Gaps = 20/302 (6%)

Query: 8   SGEAPYIIEQPLDVTVARHQPA--TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
           S   P+   QP D  VA H      L+C A G P P I+W+  G  ++  T    L A G
Sbjct: 365 SHSPPHFTHQPHDQIVALHSSGHVLLDCAASGWPQPDIQWFVNGRQLLQSTPSLQLQANG 424

Query: 66  LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
              L   +      AG Y CEA NS G+ ++  A + +  L  E    P+S+    G   
Sbjct: 425 SLILLQPN---QLSAGTYRCEARNSLGSVQA-TARIELKEL-PEILTAPQSQTIKLGKAF 479

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
           VLEC    G+P P + W+ NG  L  +        +   LV+  ARQ  AG Y+C A N 
Sbjct: 480 VLEC-DADGNPLPTIDWQLNGVPLPGNTPDLQLENENTELVVGAARQEHAGVYRCTAHNE 538

Query: 186 AGTRESAIATLKI---HIKPYLITGPEDVVAQTGSSVTFQCRVG--GDPLPDVLWRRSAG 240
            G   S  AT+K+      P L   P ++VA TG+++   C+     D L  + WR    
Sbjct: 539 NG-ETSVEATIKVERSQSPPQLAIEPSNLVAITGTTIELPCQADQPEDGL-QISWRHDGR 596

Query: 241 --GGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
               N+ L  + ++   GSL + NV + D G Y C+ +N  G  SAS  +T+ +  +++L
Sbjct: 597 LIDPNVQLAEKYQISGAGSLFVKNVTIPDGGRYECQLKNQFGRASASALVTIRN--NVDL 654

Query: 298 SP 299
           +P
Sbjct: 655 AP 656



 Score = 90.2 bits (214), Expect = 3e-16
 Identities = 75/309 (24%), Positives = 130/309 (42%), Gaps = 19/309 (6%)

Query: 199 HIKPYLITGPEDVVAQTGSS--VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS 256
           H  P+    P D +    SS  V   C   G P PD+ W  +          +++  +GS
Sbjct: 366 HSPPHFTHQPHDQIVALHSSGHVLLDCAASGWPQPDIQWFVNGRQLLQSTPSLQLQANGS 425

Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316
           L L        G Y CEA NS+G+V A+  + + + P I  +P S  ++ G      C A
Sbjct: 426 LILLQPNQLSAGTYRCEARNSLGSVQATARIELKELPEILTAPQSQTIKLGKAFVLECDA 485

Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
            G P PT+ W + G   +  PG + D      + +  T L +    + +      C+A N
Sbjct: 486 DGNPLPTIDWQLNG---VPLPGNTPD----LQLENENTELVVG-AARQEHAGVYRCTAHN 537

Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEG 435
             G + V  + T+  +  + PP +   PSN      +    PC A    + + I+W  +G
Sbjct: 538 ENGETSV--EATIKVERSQSPPQLAIEPSNLVAITGTTIELPCQADQPEDGLQISWRHDG 595

Query: 436 EALIQN----HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPIN-- 489
             +  N     +  ++  G+L +K++   D G Y C   ++ G+   S  + + + ++  
Sbjct: 596 RLIDPNVQLAEKYQISGAGSLFVKNVTIPDGGRYECQLKNQFGRASASALVTIRNNVDLA 655

Query: 490 PNIHFFRAA 498
           P   + R A
Sbjct: 656 PGDRYVRIA 664



 Score = 86.2 bits (204), Expect = 5e-15
 Identities = 70/279 (25%), Positives = 123/279 (44%), Gaps = 16/279 (5%)

Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
           V+L+C    G P+P++ W  NG+ LL    S + L   G+L++    Q  AG Y+C ARN
Sbjct: 388 VLLDCAAS-GWPQPDIQWFVNGRQLLQSTPS-LQLQANGSLILLQPNQLSAGTYRCEARN 445

Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG--GG 242
           + G+ + A A +++   P ++T P+    + G +   +C   G+PLP + W+ +     G
Sbjct: 446 SLGSVQ-ATARIELKELPEILTAPQSQTIKLGKAFVLECDADGNPLPTIDWQLNGVPLPG 504

Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDPPSINLSP 299
           N P  +++  ++  L +        G Y C A N  G  S    + V     PP + + P
Sbjct: 505 NTPDLQLE-NENTELVVGAARQEHAGVYRCTAHNENGETSVEATIKVERSQSPPQLAIEP 563

Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS-RDKYHATAVFDGVTVLTI 358
           +++   +G      C A  +PE  +  S   +  +I P +   +KY       G   L +
Sbjct: 564 SNLVAITGTTIELPCQA-DQPEDGLQISWRHDGRLIDPNVQLAEKYQ----ISGAGSLFV 618

Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397
            +    D      C   N  G +     +T+ ++ D  P
Sbjct: 619 KNVTIPDG-GRYECQLKNQFGRASASALVTIRNNVDLAP 656



 Score = 57.2 bits (132), Expect = 3e-06
 Identities = 36/130 (27%), Positives = 57/130 (43%), Gaps = 1/130 (0%)

Query: 102 HVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD 161
           H    + +F + P+  Q A G+ V L C    G   P + W  N Q L  +  ++  ++ 
Sbjct: 232 HFKCAKPQFLVAPQDAQVAAGEQVELSC-EVTGLHRPQITWMHNTQELGLEEQTQAEILP 290

Query: 162 GGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTF 221
            G+L+ + A  +D G YQCIARN  G   S    L ++   + +  P D  +    +   
Sbjct: 291 SGSLLHRSADTSDMGIYQCIARNEMGALRSQPVRLVVNGGNHPLDSPIDARSNQVWADAG 350

Query: 222 QCRVGGDPLP 231
               G  PLP
Sbjct: 351 TPTHGATPLP 360



 Score = 44.0 bits (99), Expect = 0.025
 Identities = 24/82 (29%), Positives = 35/82 (42%), Gaps = 1/82 (1%)

Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDGSLRL 259
           KP  +  P+D     G  V   C V G   P + W  +    G     + ++L  GSL  
Sbjct: 237 KPQFLVAPQDAQVAAGEQVELSCEVTGLHRPQITWMHNTQELGLEEQTQAEILPSGSLLH 296

Query: 260 DNVILADEGEYSCEAENSVGAV 281
            +   +D G Y C A N +GA+
Sbjct: 297 RSADTSDMGIYQCIARNEMGAL 318



 Score = 42.7 bits (96), Expect = 0.059
 Identities = 30/94 (31%), Positives = 38/94 (40%), Gaps = 6/94 (6%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG--VLVVSDTHRSILPAGGLFFL 69
           P  +  P D  VA  +   L+C   G   P I W      + +   T   ILP+G L   
Sbjct: 238 PQFLVAPQDAQVAAGEQVELSCEVTGLHRPQITWMHNTQELGLEEQTQAEILPSGSLLHR 297

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103
            A      SD G+Y C A N  G  RS+   L V
Sbjct: 298 SADT----SDMGIYQCIARNEMGALRSQPVRLVV 327


>UniRef50_A7RGM2 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 545

 Score =  120 bits (289), Expect = 2e-25
 Identities = 110/382 (28%), Positives = 169/382 (44%), Gaps = 26/382 (6%)

Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQ 172
           ++   + D V LE +   G P+P V W   G+ +  + + R++ +  G+   LVI++A  
Sbjct: 177 AENEVENDAVRLE-VEVTGEPKPVVLWFCEGKPI--EENRRVYTMRDGSTSVLVIENAEL 233

Query: 173 TDAGRYQCIARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231
            D   Y C A N  G  E +   L      P  +   E      GS    +  V G P P
Sbjct: 234 DDEAMYTCKAINDLGEVECSSEMLPTDEAGPKFLQRLELKEVVEGSRTDLEVEVSGKPKP 293

Query: 232 DVLWRRSAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
            V W +  G    P   + +  +G   +L + N  L DEGEY+C A+N VG VS +  L 
Sbjct: 294 VVEWLKD-GELVKPSSLMTLETEGQVHTLTIMNTTLDDEGEYTCIAKNKVGEVSCTAELL 352

Query: 289 VYD---PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345
           V +   PP   + P+S+ +  G +A+F    +G P P + W  +G    I PG    ++ 
Sbjct: 353 VEEGMRPPQFIVKPSSLQIMEGKMAKFEARVSGLPGPEVEWLRDGRP--IKPGR---RFQ 407

Query: 346 ATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPS 405
                D  +VLTI D   ND      C A + AG      +L V  D+   PP      S
Sbjct: 408 IEFEKDR-SVLTIIDAKLND-EGEYTCVATSKAGKDSCSVELLV--DEAVVPPEFVRKIS 463

Query: 406 NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDS 462
           N  L    +A F      TP P + WY +   +    R  + +D    +LV++D   SD+
Sbjct: 464 NIELTEGEIARFDVRITGTPAPEVTWYKDEVPIEDGGRFEIYSDDDKHSLVIRDCALSDT 523

Query: 463 GTYTCVASSRHGKYVWSGALLV 484
           G+Y+C A++  G+    G L +
Sbjct: 524 GSYSCKATNEAGQASCYGELTI 545



 Score =  117 bits (281), Expect = 2e-24
 Identities = 133/488 (27%), Positives = 198/488 (40%), Gaps = 60/488 (12%)

Query: 20  DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR--SILPAGGLFFLRATHGRVH 77
           D+ V      TL     GSP P + W+K G  V    HR   +   G ++ L     R  
Sbjct: 11  DIEVNEGNTVTLRIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVYTLVIKEAR-G 69

Query: 78  SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC-----LPP 132
           SD G Y C+A NS G   S   + +V VL    +  P+ +++ +  T+   C     +  
Sbjct: 70  SDTGKYLCKAYNSAGEVTS---SCNVDVLHVAPKEPPKFERNLKDITIAEGCSTRFDVQV 126

Query: 133 RGSPEPNVYWKKNGQTLL-FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
            GSPEP V+W  NG+ +   D    +H  +  +L++       +G+Y C+A N     E+
Sbjct: 127 TGSPEPKVFWYHNGKLVQPRDHVDIVHDDEHSSLILMHCPLDLSGKYTCVAENEV---EN 183

Query: 192 AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
               L++      +TG                    +P P VLW    G       RV  
Sbjct: 184 DAVRLEVE-----VTG--------------------EPKPVVLW-FCEGKPIEENRRVYT 217

Query: 252 LDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP--PSINLSPNSVNVES 306
           + DGS   L ++N  L DE  Y+C+A N +G V  S  +   D   P          V  
Sbjct: 218 MRDGSTSVLVIENAELDDEAMYTCKAINDLGEVECSSEMLPTDEAGPKFLQRLELKEVVE 277

Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG-VTVLTINDTDKND 365
           G+        +G+P+P + W  +G   ++ P         T   +G V  LTI +T  +D
Sbjct: 278 GSRTDLEVEVSGKPKPVVEWLKDGE--LVKPSSL-----MTLETEGQVHTLTIMNTTLDD 330

Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
                 C A N  G      +L V  +  RPP  I   PS+  +    MA F       P
Sbjct: 331 -EGEYTCIAKNKVGEVSCTAELLV-EEGMRPPQFIVK-PSSLQIMEGKMAKFEARVSGLP 387

Query: 426 EPIIAWYFEGEALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482
            P + W  +G  +    R  +    +   L + D   +D G YTCVA+S+ GK   S  L
Sbjct: 388 GPEVEWLRDGRPIKPGRRFQIEFEKDRSVLTIIDAKLNDEGEYTCVATSKAGKDSCSVEL 447

Query: 483 LVDSPINP 490
           LVD  + P
Sbjct: 448 LVDEAVVP 455



 Score = 94.7 bits (225), Expect = 1e-17
 Identities = 73/269 (27%), Positives = 113/269 (42%), Gaps = 16/269 (5%)

Query: 31  LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
           L     G P P + W K G LV   +  ++   G +  L   +  +  D G Y C A N 
Sbjct: 283 LEVEVSGKPKPVVEWLKDGELVKPSSLMTLETEGQVHTLTIMNTTL-DDEGEYTCIAKNK 341

Query: 91  YGTARSRNATLHVAVLR-EEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
            G        L    +R  +F ++P S Q  +G     E     G P P V W ++G+ +
Sbjct: 342 VGEVSCTAELLVEEGMRPPQFIVKPSSLQIMEGKMAKFEA-RVSGLPGPEVEWLRDGRPI 400

Query: 150 LFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL--KIHIKPYLIT 206
                 ++    D   L I DA+  D G Y C+A + AG    ++  L  +  + P  + 
Sbjct: 401 KPGRRFQIEFEKDRSVLTIIDAKLNDEGEYTCVATSKAGKDSCSVELLVDEAVVPPEFVR 460

Query: 207 GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDG---SLRLD 260
              ++    G    F  R+ G P P+V W +      +P+   GR ++  D    SL + 
Sbjct: 461 KISNIELTEGEIARFDVRITGTPAPEVTWYKD----EVPIEDGGRFEIYSDDDKHSLVIR 516

Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTV 289
           +  L+D G YSC+A N  G  S  G LT+
Sbjct: 517 DCALSDTGSYSCKATNEAGQASCYGELTI 545



 Score = 85.4 bits (202), Expect = 8e-15
 Identities = 95/411 (23%), Positives = 161/411 (39%), Gaps = 46/411 (11%)

Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---L 165
           EF+      +  +G+TV L  +   GSP+P V W K+G+ +      R  +   G    L
Sbjct: 4   EFKSALRDIEVNEGNTVTLR-IHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVYTL 62

Query: 166 VIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY----LITGPEDVVAQTGSSVTF 221
           VI++AR +D G+Y C A N+AG   S+     +H+ P          +D+    G S  F
Sbjct: 63  VIKEARGSDTGKYLCKAYNSAGEVTSSCNVDVLHVAPKEPPKFERNLKDITIAEGCSTRF 122

Query: 222 QCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281
             +V G P P V W  + G    P   V ++ D      ++IL       C  +      
Sbjct: 123 DVQVTGSPEPKVFWYHN-GKLVQPRDHVDIVHDDEH--SSLILMH-----CPLD------ 168

Query: 282 SASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341
             SG  T        ++ N V     +  R     TG P+P + W  EG           
Sbjct: 169 -LSGKYTC-------VAENEVE---NDAVRLEVEVTGEPKPVVLWFCEGKPI-------E 210

Query: 342 DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401
           +      + DG T + + +  + D      C A+N  G      ++  T  D+  P  + 
Sbjct: 211 ENRRVYTMRDGSTSVLVIENAELDDEAMYTCKAINDLGEVECSSEMLPT--DEAGPKFLQ 268

Query: 402 NGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLD 458
                + +   S           P+P++ W  +GE +  +    +  +G   TL + +  
Sbjct: 269 RLELKEVVE-GSRTDLEVEVSGKPKPVVEWLKDGELVKPSSLMTLETEGQVHTLTIMNTT 327

Query: 459 KSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTK 509
             D G YTC+A ++ G+   +  LLV+  + P     + + +  + G   K
Sbjct: 328 LDDEGEYTCIAKNKVGEVSCTAELLVEEGMRPPQFIVKPSSLQIMEGKMAK 378



 Score = 62.5 bits (145), Expect = 7e-08
 Identities = 58/210 (27%), Positives = 88/210 (41%), Gaps = 19/210 (9%)

Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDG--- 255
           I P   +   D+    G++VT +  V G P P+V W +       +P  R +V   G   
Sbjct: 1   IPPEFKSALRDIEVNEGNTVTLRIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVY 60

Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-----DPPSINLSPNSVNVESGNVA 310
           +L +     +D G+Y C+A NS G V++S  + V      +PP    +   + +  G   
Sbjct: 61  TLVIKEARGSDTGKYLCKAYNSAGEVTSSCNVDVLHVAPKEPPKFERNLKDITIAEGCST 120

Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
           RF    TG PEP +FW   G   ++ P   RD  H   V D      I      D     
Sbjct: 121 RFDVQVTGSPEPKVFWYHNGK--LVQP---RD--HVDIVHDDEHSSLILMHCPLDLSGKY 173

Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPII 400
            C A N   +  VR ++ VT +   P P++
Sbjct: 174 TCVAENEVENDAVRLEVEVTGE---PKPVV 200



 Score = 56.8 bits (131), Expect = 3e-06
 Identities = 43/183 (23%), Positives = 70/183 (38%), Gaps = 8/183 (4%)

Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
           PP    +   + V  GN        TG P+P + W  +G       G+   ++    V +
Sbjct: 2   PPEFKSALRDIEVNEGNTVTLRIHVTGSPKPEVDWFKDGKPV---SGLPHRRFEVGCVGE 58

Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
            V  L I +   +D+    +C A N AG       + V     + PP       + T+  
Sbjct: 59  -VYTLVIKEARGSDT-GKYLCKAYNSAGEVTSSCNVDVLHVAPKEPPKFERNLKDITIAE 116

Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTCV 468
                F      +PEP + WY  G+ +      ++ +D    +L+L       SG YTCV
Sbjct: 117 GCSTRFDVQVTGSPEPKVFWYHNGKLVQPRDHVDIVHDDEHSSLILMHCPLDLSGKYTCV 176

Query: 469 ASS 471
           A +
Sbjct: 177 AEN 179



 Score = 54.4 bits (125), Expect = 2e-05
 Identities = 45/178 (25%), Positives = 74/178 (41%), Gaps = 4/178 (2%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P  I +P  + +   + A    R  G P P + W + G  +       I        L  
Sbjct: 360 PQFIVKPSSLQIMEGKMAKFEARVSGLPGPEVEWLRDGRPIKPGRRFQIEFEKDRSVLTI 419

Query: 72  THGRVHSDAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
              ++ +D G Y C AT+  G  + S    +  AV+  EF  +  + +  +G+    + +
Sbjct: 420 IDAKL-NDEGEYTCVATSKAGKDSCSVELLVDEAVVPPEFVRKISNIELTEGEIARFD-V 477

Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAG 187
              G+P P V W K+   +   G   ++  D   +LVI+D   +D G Y C A N AG
Sbjct: 478 RITGTPAPEVTWYKDEVPIEDGGRFEIYSDDDKHSLVIRDCALSDTGSYSCKATNEAG 535


>UniRef50_O15394 Cluster: Neural cell adhesion molecule 2 precursor;
           n=35; Tetrapoda|Rep: Neural cell adhesion molecule 2
           precursor - Homo sapiens (Human)
          Length = 837

 Score =  120 bits (289), Expect = 2e-25
 Identities = 148/604 (24%), Positives = 239/604 (39%), Gaps = 56/604 (9%)

Query: 6   VTSGEAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
           V+SG+A   +   L  V ++  +     C A G P  +I WY      +  T R ++  G
Sbjct: 14  VSSGQALLQVTISLSKVELSVGESKFFTCTAIGEPR-SIDWYNPQGEKIISTQRVVVQKG 72

Query: 65  GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
           G+      +     DAG+Y C+AT++ G  +     L +   +  FR     ++  QG+ 
Sbjct: 73  GVRSRLTIYNANIEDAGIYRCQATDAKGQTQEATVVLEI-YQKLTFREVVSPQEFKQGED 131

Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR- 183
             + C     SP P V W  + + +    D+R+ ++   NL I +  ++D G Y+C  R 
Sbjct: 132 AEVVC-RVSSSPAPAVSWLYHNEEVTTISDNRLAMLANNNLQILNINKSDEGIYRCEGRV 190

Query: 184 NAAGTRESAIATLKIHIKPYLITGPE---DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
            A G  +     + +++ P  I+ P+   +  A+ G  +TF CR  G P P + W R+  
Sbjct: 191 EARGEIDFRDIIVIVNVPP-AISMPQKSFNATAERGEEMTFSCRASGSPEPAISWFRN-- 247

Query: 241 GGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
            G +     K +  GS   L + N+I +D G Y C A N  G      +L V+  P I  
Sbjct: 248 -GKLIEENEKYILKGSNTELTVRNIINSDGGPYVCRATNKAGEDEKQAFLQVFVQPHIIQ 306

Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFW--SVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
             N    E+G V    C A G P P + W  +V+G  T      S D         G + 
Sbjct: 307 LKNETTYENGQVT-LVCDAEGEPIPEITWKRAVDG-FTFTEGDKSPDGRIEVKGQHGSSS 364

Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
           L I D  K        C A +  G      + ++  D +  P  I+N     +     + 
Sbjct: 365 LHIKDV-KLSGSGRYDCEAASRIGGH----QKSMYLDIEYAPKFISNQTIYYSWEGNPIN 419

Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDS--GTYTCVAS 470
           +  C     P   I W  +   L   +  N+    T   ++L+    SD+  G Y C A+
Sbjct: 420 I-SCDVKSNPPASIHWRRDKLVLPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTAT 478

Query: 471 SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530
           +  G                  +    ADV   P  P       ++ T+  +S+++ +  
Sbjct: 479 NHIGTRFQE-------------YILALADV---PSSPYGVKIIELSQTTAKVSFNKPDSH 522

Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590
           G   I  YQV+V  +E          S  W ++     QT  V+ +L P  TY   V   
Sbjct: 523 GGVPIHHYQVDV--KEVA--------SEIWKIVRSHGVQTMVVLNNLEPNTTYEIRVAAV 572

Query: 591 NSHG 594
           N  G
Sbjct: 573 NGKG 576


>UniRef50_Q90478 Cluster: Neural cell adhesion molecule L1.1; n=9;
           Cyprinidae|Rep: Neural cell adhesion molecule L1.1 -
           Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 1197

 Score =  120 bits (289), Expect = 2e-25
 Identities = 129/516 (25%), Positives = 210/516 (40%), Gaps = 44/516 (8%)

Query: 39  PSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRN 98
           PSP+ RW K G          +L   G      T   +H   G Y C A N  GTA S  
Sbjct: 7   PSPSFRWVKDG-----KQFGEVLSESGTLTPHPTMD-LHFYQGTYRCYAANELGTAVSNL 60

Query: 99  ATLHVAVLREEFRLEPESKQSAQ-GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM 157
             L    +    +++ + +++ + G++ VL C PP+ S  P ++W  + Q      + R+
Sbjct: 61  VHLTTEPVPSLAKVKKQKRRAYEVGESAVLRCNPPKSSVTPKIHW-MDMQFHHIPLNERV 119

Query: 158 HLVDGGNLVIQDARQTDA-GRYQCIARNAAGTRESAIATLKIHIKP-------------Y 203
            +   GNL   +    D+   Y C A     +       + I++ P             +
Sbjct: 120 TISRDGNLYFANLIANDSRDDYTCNAHYINASIILPKEPMSIYVTPSNSVVKNRRAKLHH 179

Query: 204 LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVI 263
                   +   G ++T QC   G P P+V W R       P    K+ ++  L++DNV+
Sbjct: 180 PAGARSSYLVLRGQTLTLQCIPEGLPTPEVHWDR-IDSALSPNRTKKLYNNRWLQIDNVL 238

Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPT 323
            +D+GEY C A NS  +V     +TV   P    SP       G   R  C A G P P 
Sbjct: 239 ESDDGEYVCTARNSENSVKHHYTVTVEAAPYWTRSPEEHLYAPGETVRLDCKADGIPAPN 298

Query: 324 MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383
           + WS+ G      P    D      V  G  +L  ++ + +D+     C AVN  GS  +
Sbjct: 299 ITWSING-----VPVSGTDVDPRRRVSSGKLIL--SNVEFSDTA-VYQCEAVNKHGSILI 350

Query: 384 RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-YFEGEALIQNH 442
              + V    + P  I+T              +  C    +P P I W   +    + N 
Sbjct: 351 NTHVHVV---ELPAQILTPDERLYQATAGQTVMLDCRTFGSPLPKIHWEILDSIPALSNA 407

Query: 443 RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPI-NP--NIHFFRAAD 499
           + + T +G+L + ++ + DS  YTC  S  +        +L  + I  P  N+H  R +D
Sbjct: 408 KISQTTNGSLKISNVSEEDSNRYTCSVSETNKSISADVEVLNRTKIVGPPQNLHVIRGSD 467

Query: 500 VSSLPGPPTKPITHNVTDTSVTLSWSQN-NKIGSSS 534
            + L    T  + HN+   S T+ W+++ +KI +S+
Sbjct: 468 -AILHCKYT--VDHNL--KSPTVQWNKDGHKITAST 498



 Score =  111 bits (266), Expect = 1e-22
 Identities = 180/806 (22%), Positives = 312/806 (38%), Gaps = 64/806 (7%)

Query: 23  VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
           V R Q  TL C   G P+P + W +    +  +  + +     L         + SD G 
Sbjct: 189 VLRGQTLTLQCIPEGLPTPEVHWDRIDSALSPNRTKKLYNNRWL----QIDNVLESDDGE 244

Query: 83  YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW 142
           Y C A NS  + +  + T+ V       R  PE    A G+TV L+C    G P PN+ W
Sbjct: 245 YVCTARNSENSVK-HHYTVTVEAAPYWTR-SPEEHLYAPGETVRLDC-KADGIPAPNITW 301

Query: 143 KKNGQTLL-FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI- 200
             NG  +   D D R   V  G L++ +   +D   YQC A N  G   S +    +H+ 
Sbjct: 302 SINGVPVSGTDVDPRRR-VSSGKLILSNVEFSDTAVYQCEAVNKHG---SILINTHVHVV 357

Query: 201 -KPYLITGPEDVV--AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257
             P  I  P++ +  A  G +V   CR  G PLP + W        +   ++    +GSL
Sbjct: 358 ELPAQILTPDERLYQATAGQTVMLDCRTFGSPLPKIHWEILDSIPALSNAKISQTTNGSL 417

Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
           ++ NV   D   Y+C    +  ++SA   + V +   I   P +++V  G+ A   C  T
Sbjct: 418 KISNVSEEDSNRYTCSVSETNKSISAD--VEVLNRTKIVGPPQNLHVIRGSDAILHCKYT 475

Query: 318 ---GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
                  PT+ W+ +G++  I    S DKYH   +   + VL +   D         C  
Sbjct: 476 VDHNLKSPTVQWNKDGHK--ITASTSNDKYH--EIEGSLKVLDVQMED----MGIYSCEV 527

Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFE 434
                S    G +TV    D P  +  +    +++ I  M      +  T E +I    E
Sbjct: 528 STTLDSDTASGYITVQDKPDPPQSLKLSEKMERSVTISWMPSVENNSPVT-EYVIEMN-E 585

Query: 435 GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHF 494
           GE   +   +   +    V +D+   DS    C  S  H +     ++   +P   ++ +
Sbjct: 586 GETPDEGQWQKYRS----VSQDI---DSWRSICSYSKYHFQIRAVNSIGTSAPTESSLSY 638

Query: 495 FRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETL-SGNNT 553
             +   +     P   +T +    S+ +SW + ++   +   G+Q +VF R    SG + 
Sbjct: 639 --STPAAKPDTNPENVMTLSTDPKSMIISWQEMDRRQFNG-PGFQYKVFWRRAADSGAHW 695

Query: 554 PRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNS 613
             +S         V     +V +    +++   V+  N  G + P P++     G+D   
Sbjct: 696 TESS---------VSNPPLMVNNTGTFVSFEIKVQAVNDLG-AAPEPLTVIGYSGEDFP- 744

Query: 614 LWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDN 673
             E     + TE +    T  +V      P   +   L ++I  +  ++G   +  P   
Sbjct: 745 -LEAPSALSVTELQK---TSVMVRWSPVRPESVRGHLLGYKI--YLRMKG-SQWETPGRA 797

Query: 674 ITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDG 733
           ++       I    D +   ++ L+ Y+ Y   +  F  K EG P +     T +  P G
Sbjct: 798 VSSSGNPTVIEVPADAAEKIVSDLQFYSDYTLTITAFNSKGEG-PHSEESFSTPEGAP-G 855

Query: 734 PPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT 793
           P + +     + + + L+W  P     NG I GY +    + + +       +  +   T
Sbjct: 856 PVLFLPFDSPSESEITLRWEAP--HKPNGEIRGYLLQYQEVVIGSESPQHVESIDLPAVT 913

Query: 794 SLIMTNLTSGVSYSVQIAAETIIGLG 819
              + NL     Y+  ++A    G G
Sbjct: 914 EFTLKNLNPESRYTFHLSARNDAGDG 939



 Score =  108 bits (260), Expect = 8e-22
 Identities = 84/295 (28%), Positives = 136/295 (46%), Gaps = 17/295 (5%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAG 64
           VT   APY    P +   A  +   L+C+A G P+P I W   GV V  +D       + 
Sbjct: 262 VTVEAAPYWTRSPEEHLYAPGETVRLDCKADGIPAPNITWSINGVPVSGTDVDPRRRVSS 321

Query: 65  GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQG 122
           G   L        SD  VY CEA N +G+    N  +HV  L  +  L P+ +  Q+  G
Sbjct: 322 GKLILSNVE---FSDTAVYQCEAVNKHGSILI-NTHVHVVELPAQI-LTPDERLYQATAG 376

Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
            TV+L+C    GSP P ++W+          ++++     G+L I +  + D+ RY C  
Sbjct: 377 QTVMLDCRT-FGSPLPKIHWEILDSIPALS-NAKISQTTNGSLKISNVSEEDSNRYTC-- 432

Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD---PLPDVLWRRSA 239
            + + T +S  A +++  +  ++  P+++    GS     C+   D     P V W +  
Sbjct: 433 -SVSETNKSISADVEVLNRTKIVGPPQNLHVIRGSDAILHCKYTVDHNLKSPTVQWNKDG 491

Query: 240 GGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
                     K  + +GSL++ +V + D G YSCE   ++ + +ASGY+TV D P
Sbjct: 492 HKITASTSNDKYHEIEGSLKVLDVQMEDMGIYSCEVSTTLDSDTASGYITVQDKP 546


>UniRef50_UPI0000ECD748 Cluster: UPI0000ECD748 related cluster; n=1;
            Gallus gallus|Rep: UPI0000ECD748 UniRef100 entry - Gallus
            gallus
          Length = 2179

 Score =  120 bits (288), Expect = 3e-25
 Identities = 106/352 (30%), Positives = 151/352 (42%), Gaps = 25/352 (7%)

Query: 2    SDDYVTSGEAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYK--GGVLVVSDTH- 57
            S ++ T GE P II +    +++     A + C A G P P I W K   G L+ + T  
Sbjct: 1828 SSNFRTPGERPKIITKGSQSISILAETDALIPCDAVGEPKPFITWTKVSTGALMTAHTRL 1887

Query: 58   -RSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPES 116
             R  +   G F +R    +   D G Y C A N +G  +   A   VA   +      + 
Sbjct: 1888 QRFEVLKNGTFLIRNAQLQ---DRGQYLCTAQNLHGIDKMIFALTVVAHQPKILLSRYQD 1944

Query: 117  KQSAQGDTVVLECLPPRGSPEPNVYW----KKNGQTLLFDGDSRMHLVDGGNLVIQDARQ 172
                 GDT+ LEC    G+P P++ W     K  QT+    +SR+ L +   L I+ A  
Sbjct: 1945 VTVYFGDTIALEC-QASGTPSPHISWIFPDTKILQTVTTT-ESRIMLHENRTLSIKQATF 2002

Query: 173  TDAGRYQCIARNAAGTRESAIATLKIHIKPYLI--TGPEDVVAQTGSSVTFQCRVGGDPL 230
            +D G Y+C+A NAAG  +S    L I   P +I     E++    GSS+   C     P 
Sbjct: 2003 SDRGVYKCVASNAAGA-DSIAVRLHIAALPPIIQQDKQENISLPLGSSINIHCTAKAAPS 2061

Query: 231  PDVLWRRSAGGGNMPL----GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY 286
            P + W    G    P     G + V  +G+L + NV   D G Y C A N VGA      
Sbjct: 2062 PSIRWVLFDGTQIRPSQFVNGNLFVFPNGTLYIRNVSPKDSGIYECIAANMVGAARRIIQ 2121

Query: 287  LTVYDPPS----INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334
            L V    S       SP   +V  G++    C+A+G P P + W +   R I
Sbjct: 2122 LHVKKQASNAKITGSSPQRTDVTYGSILHLDCSASGDPWPRILWRLPSKRMI 2173



 Score = 94.7 bits (225), Expect = 1e-17
 Identities = 82/288 (28%), Positives = 123/288 (42%), Gaps = 24/288 (8%)

Query: 201  KPYLIT-GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP----LGRVKVLDDG 255
            +P +IT G + +     +     C   G+P P + W + + G  M     L R +VL +G
Sbjct: 1837 RPKIITKGSQSISILAETDALIPCDAVGEPKPFITWTKVSTGALMTAHTRLQRFEVLKNG 1896

Query: 256  SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-DPPSINLSP-NSVNVESGNVARFT 313
            +  + N  L D G+Y C A+N  G       LTV    P I LS    V V  G+     
Sbjct: 1897 TFLIRNAQLQDRGQYLCTAQNLHGIDKMIFALTVVAHQPKILLSRYQDVTVYFGDTIALE 1956

Query: 314  CTATGRPEPTMFWSVEGNRTI--IFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371
            C A+G P P + W     + +  +    SR   H          L+I     +D R    
Sbjct: 1957 CQASGTPSPHISWIFPDTKILQTVTTTESRIMLHENRT------LSIKQATFSD-RGVYK 2009

Query: 372  CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431
            C A N AG+  +  +L + +    PP I  +   N +LP+ S     CTA   P P I W
Sbjct: 2010 CVASNAAGADSIAVRLHIAA---LPPIIQQDKQENISLPLGSSINIHCTAKAAPSPSIRW 2066

Query: 432  -YFEGEAL----IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
              F+G  +      N    V  +GTL ++++   DSG Y C+A++  G
Sbjct: 2067 VLFDGTQIRPSQFVNGNLFVFPNGTLYIRNVSPKDSGIYECIAANMVG 2114



 Score = 51.2 bits (117), Expect = 2e-04
 Identities = 35/110 (31%), Positives = 52/110 (47%), Gaps = 6/110 (5%)

Query: 397  PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-YFEGEALIQNHRR----NVTNDGT 451
            P IIT G  + ++  ++ A+ PC A+  P+P I W      AL+  H R     V  +GT
Sbjct: 1838 PKIITKGSQSISILAETDALIPCDAVGEPKPFITWTKVSTGALMTAHTRLQRFEVLKNGT 1897

Query: 452  LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVS 501
             ++++    D G Y C A + HG      AL V +   P I   R  DV+
Sbjct: 1898 FLIRNAQLQDRGQYLCTAQNLHGIDKMIFALTVVAH-QPKILLSRYQDVT 1946



 Score = 50.0 bits (114), Expect = 4e-04
 Identities = 47/188 (25%), Positives = 79/188 (42%), Gaps = 17/188 (9%)

Query: 105 VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL---FDG-DSRMHLV 160
           ++ E+ +   +++   +G    L C   + S  P + W     T L   F+  DSR  ++
Sbjct: 470 IMIEQNQSTRKAQSVVEGSECQLNC-NVKASERPFIQWLFPDGTKLQAPFNQKDSRFSIL 528

Query: 161 DGGNLVIQDARQTDAGRYQCIARNAAGTRESA-IATLKIHIKPYLI-TGPEDVV---AQT 215
             G LVI+    TDAG Y CIA+     R+   +   ++ ++P  I     D+V      
Sbjct: 529 TSGQLVIKPVSYTDAGLYHCIAQ----VRDDIDVMAYRLLVQPPAIQVADSDIVRVEKNV 584

Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK---VLDDGSLRLDNVILADEGEYSC 272
           G  +   C     P   + W   +      L       VLD+G+L +    ++D G Y C
Sbjct: 585 GDPIVLPCSAIASPEAQLSWILPSSQVLNVLSNFSKGYVLDNGTLLIPKSHISDSGHYRC 644

Query: 273 EAENSVGA 280
            A N +G+
Sbjct: 645 VAVNQLGS 652



 Score = 47.6 bits (108), Expect = 0.002
 Identities = 46/177 (25%), Positives = 77/177 (43%), Gaps = 17/177 (9%)

Query: 22  TVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVS-----DTHRSILPAGGLFFLRATHGR 75
           +V       LNC    S  P I+W +  G  + +     D+  SIL +G L     +   
Sbjct: 483 SVVEGSECQLNCNVKASERPFIQWLFPDGTKLQAPFNQKDSRFSILTSGQLVIKPVS--- 539

Query: 76  VHSDAGVYWC--EATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
            ++DAG+Y C  +  +       R      A+   +  +    K    GD +VL C    
Sbjct: 540 -YTDAGLYHCIAQVRDDIDVMAYRLLVQPPAIQVADSDIVRVEKN--VGDPIVLPC-SAI 595

Query: 134 GSPEPNVYW-KKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
            SPE  + W   + Q L +    S+ +++D G L+I  +  +D+G Y+C+A N  G+
Sbjct: 596 ASPEAQLSWILPSSQVLNVLSNFSKGYVLDNGTLLIPKSHISDSGHYRCVAVNQLGS 652



 Score = 40.7 bits (91), Expect = 0.24
 Identities = 22/63 (34%), Positives = 35/63 (55%), Gaps = 4/63 (6%)

Query: 416 VFPCTAICTPEPIIAWYFEGEALIQ---NHRRN-VTNDGTLVLKDLDKSDSGTYTCVASS 471
           V PC+AI +PE  ++W      ++    N  +  V ++GTL++     SDSG Y CVA +
Sbjct: 589 VLPCSAIASPEAQLSWILPSSQVLNVLSNFSKGYVLDNGTLLIPKSHISDSGHYRCVAVN 648

Query: 472 RHG 474
           + G
Sbjct: 649 QLG 651



 Score = 37.1 bits (82), Expect = 2.9
 Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 6/75 (8%)

Query: 419 CTAICTPEPIIAWYFEGEALIQ------NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
           C    +  P I W F     +Q      + R ++   G LV+K +  +D+G Y C+A  R
Sbjct: 494 CNVKASERPFIQWLFPDGTKLQAPFNQKDSRFSILTSGQLVIKPVSYTDAGLYHCIAQVR 553

Query: 473 HGKYVWSGALLVDSP 487
               V +  LLV  P
Sbjct: 554 DDIDVMAYRLLVQPP 568


>UniRef50_A7S4D5 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 637

 Score =  118 bits (285), Expect = 7e-25
 Identities = 66/193 (34%), Positives = 97/193 (50%), Gaps = 8/193 (4%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
           + P  +E+P  V   R     +NC    +P     W K G  +  D    +L +G L  +
Sbjct: 23  QPPRFVEEPSAVIALRKSTVQINCSTIATPVARTIWLKDGARIKPDDRHVVLTSGALR-I 81

Query: 70  RATHGR---VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
           ++  GR     +D GVY C A+N  GT  SR  TLH+AVL  +F  +P+S  + +G T  
Sbjct: 82  QSVQGRRKGFGNDEGVYQCLASNRAGTVASRKVTLHIAVLSRKFEEQPQSINAWEGTTAR 141

Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNA 185
             C   +  P P++ W+ NGQ ++    S+ H+V   G L I + +Q D G YQC+A N 
Sbjct: 142 FSCKVKKAYPAPSISWEHNGQVIV---PSKRHVVLPNGALQIHNVQQVDQGTYQCVASNI 198

Query: 186 AGTRESAIATLKI 198
           A  R S  ATL +
Sbjct: 199 ARIRRSNTATLTV 211



 Score = 71.3 bits (167), Expect = 1e-10
 Identities = 46/152 (30%), Positives = 73/152 (48%), Gaps = 9/152 (5%)

Query: 666 IYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQ 725
           I ++P D  + E +   ++ + D +   I SL  +TKY F++ PF+ K +G  S     Q
Sbjct: 494 INYQPADKSSKELQ---VVLAKDFTSEVIRSLSGFTKYTFYVTPFFTKGQGLNSEVITVQ 550

Query: 726 TLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAI 785
           TL   P   P NI +  L   ++ + W PP  + +NGI+T Y +  +      NKS+   
Sbjct: 551 TLPGKPSTSPGNIVLNSLTPDSIDVSWDPPPKRYRNGILTSYIIKYH------NKSISET 604

Query: 786 NTTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817
                      ++ L SG  Y VQ+AA T +G
Sbjct: 605 ILLPSSMQKKTISGLASGEVYMVQVAAATKMG 636



 Score = 69.3 bits (162), Expect = 6e-10
 Identities = 53/171 (30%), Positives = 79/171 (46%), Gaps = 10/171 (5%)

Query: 113 EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV--IQDA 170
           EP +  + +  TV + C     +P     W K+G  +  D D  + L  G   +  +Q  
Sbjct: 30  EPSAVIALRKSTVQINC-STIATPVARTIWLKDGARIKPD-DRHVVLTSGALRIQSVQGR 87

Query: 171 RQ---TDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG-PEDVVAQTGSSVTFQCRVG 226
           R+    D G YQC+A N AGT  S   TL I +        P+ + A  G++  F C+V 
Sbjct: 88  RKGFGNDEGVYQCLASNRAGTVASRKVTLHIAVLSRKFEEQPQSINAWEGTTARFSCKVK 147

Query: 227 -GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAEN 276
              P P + W  + G   +P  R  VL +G+L++ NV   D+G Y C A N
Sbjct: 148 KAYPAPSISWEHN-GQVIVPSKRHVVLPNGALQIHNVQQVDQGTYQCVASN 197



 Score = 60.5 bits (140), Expect = 3e-07
 Identities = 83/344 (24%), Positives = 131/344 (38%), Gaps = 39/344 (11%)

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDN 261
           P  +  P  V+A   S+V   C     P+   +W +  G    P  R  VL  G+LR+ +
Sbjct: 25  PRFVEEPSAVIALRKSTVQINCSTIATPVARTIWLKD-GARIKPDDRHVVLTSGALRIQS 83

Query: 262 V------ILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLSPNSVNVESGNVARF 312
           V         DEG Y C A N  G V AS  +T++           P S+N   G  ARF
Sbjct: 84  VQGRRKGFGNDEGVYQCLASNRAGTV-ASRKVTLHIAVLSRKFEEQPQSINAWEGTTARF 142

Query: 313 TC-TATGRPEPTMFWS------VEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
           +C      P P++ W       V   R ++ P  +   ++   V  G      ++  +  
Sbjct: 143 SCKVKKAYPAPSISWEHNGQVIVPSKRHVVLPNGALQIHNVQQVDQGTYQCVASNIARIR 202

Query: 366 SRN--TIVCSAVNYAG----SSFV-RGKL-------TVTSDDDRPPPIITNGPSNQTLPI 411
             N  T+    V + G    ++F+ + K+       +         P  T  PSN ++  
Sbjct: 203 RSNTATLTVQQVLWQGRIAPTAFLPKVKVIYLGTYCSFIKTKSSKQPNFTTIPSNTSVIS 262

Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG--TLVLKDLDKSDSGTYTCVA 469
              AV  C A   P P + W   G A  + +  ++   G   L ++     D G Y C+ 
Sbjct: 263 GEEAVLECIATGVPVPTVQWKKVGGA-DRAYDYSLAKPGGCNLRIRSASPKDGGEYMCIV 321

Query: 470 SSRHGKYVWSGALLVDSPINPNIHFFRAAD---VSSLPGPPTKP 510
           S+       S  L V   +  ++ FF   +   V  LP   +KP
Sbjct: 322 SASGRSMTHSTFLSVQGRL-VDLDFFVVCNFRRVFFLPSVYSKP 364



 Score = 59.7 bits (138), Expect = 5e-07
 Identities = 55/206 (26%), Positives = 86/206 (41%), Gaps = 16/206 (7%)

Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR------TIIFPGMSRDKYHA 346
           P+    P++ +V SG  A   C ATG P PT+ W   G        ++  PG    +  +
Sbjct: 249 PNFTTIPSNTSVISGEEAVLECIATGVPVPTVQWKKVGGADRAYDYSLAKPGGCNLRIRS 308

Query: 347 TAVFDGVTVLTI-NDTDKNDSRNTIVCSAVNYAGSSFV-----RGKLTVTSDDDRPPPII 400
            +  DG   + I + + ++ + +T +          F      R    + S   +PP  I
Sbjct: 309 ASPKDGGEYMCIVSASGRSMTHSTFLSVQGRLVDLDFFVVCNFRRVFFLPSVYSKPPHFI 368

Query: 401 TNGPS--NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLD 458
            N P      L I +     C+A   P P I W   G+ L+ N R++  N+  LV++ L 
Sbjct: 369 -NTPKLPKGLLDIGATLTLQCSATGVPPPRITWLKNGKELVGNQRQSGINN-DLVIQSLS 426

Query: 459 KSDSGTYTCVASSRHGKYVWSGALLV 484
             DSG Y C A +  G    S  +LV
Sbjct: 427 TKDSGVYQCFAENDIGSVQTSTRVLV 452



 Score = 52.0 bits (119), Expect = 1e-04
 Identities = 56/218 (25%), Positives = 87/218 (39%), Gaps = 34/218 (15%)

Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK-NGQTLLFDGDSRMHLVDGGNLVIQ 168
           F   P +     G+  VLEC+   G P P V WKK  G    +D    +    G NL I+
Sbjct: 251 FTTIPSNTSVISGEEAVLECIAT-GVPVPTVQWKKVGGADRAYDYS--LAKPGGCNLRIR 307

Query: 169 DARQTDAGRYQCI--ARNAAGTRESAIATL---------------------KIHIKP-YL 204
            A   D G Y CI  A   + T  + ++                        ++ KP + 
Sbjct: 308 SASPKDGGEYMCIVSASGRSMTHSTFLSVQGRLVDLDFFVVCNFRRVFFLPSVYSKPPHF 367

Query: 205 ITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDN 261
           I  P+    +   G+++T QC   G P P + W ++   G   +G  +    +  L + +
Sbjct: 368 INTPKLPKGLLDIGATLTLQCSATGVPPPRITWLKN---GKELVGNQRQSGINNDLVIQS 424

Query: 262 VILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
           +   D G Y C AEN +G+V  S  + V     +N  P
Sbjct: 425 LSTKDSGVYQCFAENDIGSVQTSTRVLVRRSGKLNTYP 462



 Score = 47.2 bits (107), Expect = 0.003
 Identities = 46/199 (23%), Positives = 72/199 (36%), Gaps = 18/199 (9%)

Query: 279 GAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPG 338
           G  +  G   +  PP     P++V     +  +  C+    P     W  +G R      
Sbjct: 11  GNFAVLGSSNLLQPPRFVEEPSAVIALRKSTVQINCSTIATPVARTIWLKDGAR------ 64

Query: 339 MSRDKYHATAVFDGVTVLTINDTDKN--DSRNTIVCSAVNYAG---SSFVRGKLTVTSDD 393
           +  D  H       + + ++    K   +      C A N AG   S  V   + V S  
Sbjct: 65  IKPDDRHVVLTSGALRIQSVQGRRKGFGNDEGVYQCLASNRAGTVASRKVTLHIAVLSRK 124

Query: 394 DRPPPIITNGPSNQTLPIKSMAVFPCTAI-CTPEPIIAWYFEGEALIQNHRRNVTNDGTL 452
               P   N     T      A F C      P P I+W   G+ ++ + R  V  +G L
Sbjct: 125 FEEQPQSINAWEGTT------ARFSCKVKKAYPAPSISWEHNGQVIVPSKRHVVLPNGAL 178

Query: 453 VLKDLDKSDSGTYTCVASS 471
            + ++ + D GTY CVAS+
Sbjct: 179 QIHNVQQVDQGTYQCVASN 197



 Score = 46.8 bits (106), Expect = 0.004
 Identities = 30/100 (30%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 16  EQPLDVTVARHQPATLNCRAGGS-PSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74
           EQP  +       A  +C+   + P+P+I W   G ++V      +LP G L      H 
Sbjct: 127 EQPQSINAWEGTTARFSCKVKKAYPAPSISWEHNGQVIVPSKRHVVLPNGAL----QIHN 182

Query: 75  RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP 114
               D G Y C A+N     RS  ATL V  +  + R+ P
Sbjct: 183 VQQVDQGTYQCVASNIARIRRSNTATLTVQQVLWQGRIAP 222



 Score = 39.1 bits (87), Expect = 0.72
 Identities = 36/123 (29%), Positives = 51/123 (41%), Gaps = 15/123 (12%)

Query: 30  TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
           TL C A G P P I W K G  +V +  +S     G+            D+GVY C A N
Sbjct: 385 TLQCSATGVPPPRITWLKNGKELVGNQRQS-----GINNDLVIQSLSTKDSGVYQCFAEN 439

Query: 90  SYGTARSRNATLHVAVLREEFRLEPESKQSAQG-----DTVVLECLPPRGSPEPNVYWKK 144
             G+ ++    L    +R   +L      +  G     + V +  LPPRG PE  + +  
Sbjct: 440 DIGSVQTSTRVL----VRRSGKLNTYPPLNVTGVGISSEEVNISWLPPRG-PEQVLAYSI 494

Query: 145 NGQ 147
           N Q
Sbjct: 495 NYQ 497



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 30/104 (28%), Positives = 46/104 (44%), Gaps = 3/104 (2%)

Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
           GT  S I T K   +P   T P +    +G     +C   G P+P V W++  GG +   
Sbjct: 235 GTYCSFIKT-KSSKQPNFTTIPSNTSVISGEEAVLECIATGVPVPTVQWKK-VGGADRAY 292

Query: 247 GRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
                   G +LR+ +    D GEY C    S  +++ S +L+V
Sbjct: 293 DYSLAKPGGCNLRIRSASPKDGGEYMCIVSASGRSMTHSTFLSV 336



 Score = 36.7 bits (81), Expect = 3.9
 Identities = 24/84 (28%), Positives = 34/84 (40%), Gaps = 6/84 (7%)

Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKD 456
           PP     PS      KS     C+ I TP     W  +G  +  + R  V   G L ++ 
Sbjct: 24  PPRFVEEPSAVIALRKSTVQINCSTIATPVARTIWLKDGARIKPDDRHVVLTSGALRIQS 83

Query: 457 LDK------SDSGTYTCVASSRHG 474
           +        +D G Y C+AS+R G
Sbjct: 84  VQGRRKGFGNDEGVYQCLASNRAG 107


>UniRef50_UPI00015B5045 Cluster: PREDICTED: similar to receptor
           tyrosine phosphatase type r2a; n=1; Nasonia
           vitripennis|Rep: PREDICTED: similar to receptor tyrosine
           phosphatase type r2a - Nasonia vitripennis
          Length = 2046

 Score =  118 bits (284), Expect = 1e-24
 Identities = 99/359 (27%), Positives = 157/359 (43%), Gaps = 30/359 (8%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRS---ILPAGGLFF 68
           P  I++P    V     A+  C A GSP P I W K    ++S    +   + P      
Sbjct: 40  PRFIQKPQSQMVKNGGIASFFCSASGSPPPQIFWRKNNKKIMSTNQSNRFMVYPYENGTL 99

Query: 69  LRATHGRVHSDAGVYWCEATNSYGTARSRNATL---HVAVLREEFRL---EPESKQSAQG 122
           LR    R + DA  Y C A N  G A S  A+L    V  L + F +    P +K   +G
Sbjct: 100 LRIEPVRSNRDAIAYECLAENGVGDAVSATASLTIYEVDKLPKGFPMITQAPTTKVVEKG 159

Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
               L C    GSP P + W +N Q  +   + R  +++ G L I D+   D G+Y+C+A
Sbjct: 160 HNAQLSC-SAMGSPMPIISWMRN-QLPIDTSNPRYVVLESGALQITDSDPDDQGKYECVA 217

Query: 183 RNAAGTRESAIATLKIHIK---PYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRS 238
            N+ GT  S    L + I+   P+    P+ VV  T G S    C   G P+P V WR+ 
Sbjct: 218 TNSVGTEYSKSTQLYVKIRRVLPHFSRQPDPVVEVTLGESTNLTCVAYGSPMPYVKWRKE 277

Query: 239 AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
                 P  ++  +    L L NV   +   Y+C A++ +G ++ + Y+ V    S+ L+
Sbjct: 278 PATDLTPDNQMPPIGKNVLHLKNV--HESANYTCIAQSDLGVINTTTYVKV---RSLPLA 332

Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
           P +V      V+  T T+       + WS +G  ++ +  +     HA   +  ++ +T
Sbjct: 333 PENV-----QVSEITATSV-----KLTWSYKGPESLAYYVIQHKPKHAHQAYAEISGIT 381



 Score = 82.2 bits (194), Expect = 8e-14
 Identities = 57/187 (30%), Positives = 85/187 (45%), Gaps = 7/187 (3%)

Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
           PP     P S  V++G +A F C+A+G P P +FW  + N+ I+    S +++      +
Sbjct: 39  PPRFIQKPQSQMVKNGGIASFFCSASGSPPPQIFWR-KNNKKIMSTNQS-NRFMVYPYEN 96

Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSF-VRGKLTVTSDDDRPP--PIITNGPSNQT 408
           G T+L I     N       C A N  G +      LT+   D  P   P+IT  P+ + 
Sbjct: 97  G-TLLRIEPVRSNRDAIAYECLAENGVGDAVSATASLTIYEVDKLPKGFPMITQAPTTKV 155

Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
           +     A   C+A+ +P PII+W      +   N R  V   G L + D D  D G Y C
Sbjct: 156 VEKGHNAQLSCSAMGSPMPIISWMRNQLPIDTSNPRYVVLESGALQITDSDPDDQGKYEC 215

Query: 468 VASSRHG 474
           VA++  G
Sbjct: 216 VATNSVG 222



 Score = 68.5 bits (160), Expect = 1e-09
 Identities = 57/207 (27%), Positives = 90/207 (43%), Gaps = 8/207 (3%)

Query: 619 GVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEY 678
           GV N+T Y          E ++ + I + ++KL W       L    I  +P        
Sbjct: 316 GVINTTTYVKVRSLPLAPENVQVSEITATSVKLTWSYKGPESLAYYVIQHKPKHAHQAYA 375

Query: 679 EMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINI 738
           E+  I        + + SL  YT+YEFF+I       G PS+  V  T +  P   P  +
Sbjct: 376 EISGIT----TMYYMVRSLSPYTEYEFFVIAVNDIGRGPPSSPVVVTTGETKPGSAPRRV 431

Query: 739 EMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMT 798
           ++  L++TT  ++W  PE    NG +TGY V     D     S     T  +   + I +
Sbjct: 432 QVRPLSSTTALIQWDEPE--TPNGQVTGYKVYYT-TDSGQPMSNWQFQTVDNNQLTTI-S 487

Query: 799 NLTSGVSYSVQIAAETIIGLGPFSQKV 825
           +LT+   Y++++ A T +G GP S  V
Sbjct: 488 DLTAHAIYTIRVQALTSVGPGPLSSPV 514



 Score = 66.9 bits (156), Expect = 3e-09
 Identities = 55/213 (25%), Positives = 100/213 (46%), Gaps = 13/213 (6%)

Query: 639 IEATPIDSKTIKLMWEILNFYYLEGLFIYFRP--LDNITIEYEMKTILHSNDVSGFEITS 696
           +   P    +I + WE        G  +Y++   ++N   + E  +I+  N    F +  
Sbjct: 625 VTGLPTSPTSILVKWEPPPVERSNGRIVYYKLHYVENGRSDSE-SSIVTLNGTE-FVLDE 682

Query: 697 LRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPE 756
           L+K+T+Y  +++      +G PS     +T +DVP G P N++   +N T ++++W PP+
Sbjct: 683 LKKWTEYRIWVVAGTSVGDGPPSYPITVRTHEDVP-GDPQNVKATPINATAIYVEWEPPK 741

Query: 757 LQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTS---GVSYSVQIAAE 813
            + +NGII GY+V V  +       +     ++     ++  N++       Y VQ+AA 
Sbjct: 742 SKERNGIIRGYHVHVQEVSEETKNQLNDPIRSISLEEDVLHVNISGLQPDTRYDVQVAAL 801

Query: 814 TIIGLG----PFSQKVYFNIDSR-SVGLDLLSR 841
           T  G G    P S K    + SR S+ +  +SR
Sbjct: 802 TRKGDGARSIPVSVKTPGGVPSRPSLIIKTISR 834



 Score = 58.4 bits (135), Expect = 1e-06
 Identities = 41/134 (30%), Positives = 60/134 (44%), Gaps = 12/134 (8%)

Query: 728  DDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINT 787
            +  P GPP N+        TV + W PP+ + +NG I  YN  V +     + S V  N 
Sbjct: 917  EGAPTGPPTNLSFHFQTPDTVCVTWDPPQQKFRNGKIVSYN--VQFHKKSDHTSEVTRNI 974

Query: 788  TVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGE 847
            T    T  + TNL     Y   + A T  G GP+S+K+    D + +G     R PM+ +
Sbjct: 975  T---KTRAVFTNLDENTEYVFHVKAYTSRGGGPYSEKITILTD-KDIG-----RAPMSVK 1025

Query: 848  VSIVAGDFVMETWF 861
             +I   D   E W+
Sbjct: 1026 -AIATSDSSAEVWW 1038



 Score = 51.2 bits (117), Expect = 2e-04
 Identities = 34/134 (25%), Positives = 62/134 (46%), Gaps = 4/134 (2%)

Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751
           + +T+L   T Y  +L    ++ EG  +     +T   VP  PP N+     + T++ +K
Sbjct: 579 YTLTNLYPNTLYYVWLAARSQRGEGATTIPLPVRTEQYVPGAPPRNVTGLPTSPTSILVK 638

Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811
           W PP ++  NG I  Y   +++++   + S  +I T     T  ++  L     Y + + 
Sbjct: 639 WEPPPVERSNGRIVYYK--LHYVENGRSDSESSIVTL--NGTEFVLDELKKWTEYRIWVV 694

Query: 812 AETIIGLGPFSQKV 825
           A T +G GP S  +
Sbjct: 695 AGTSVGDGPPSYPI 708



 Score = 35.5 bits (78), Expect = 8.9
 Identities = 43/205 (20%), Positives = 83/205 (40%), Gaps = 13/205 (6%)

Query: 639 IEATPIDSKTIKLMWEILNFY----YLEGLFIYFRPLDNIT---IEYEMKTILHSNDVSG 691
           ++ATPI++  I + WE          + G  ++ + +   T   +   +++I    DV  
Sbjct: 723 VKATPINATAIYVEWEPPKSKERNGIIRGYHVHVQEVSEETKNQLNDPIRSISLEEDVLH 782

Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFIL-NTTTVHL 750
             I+ L+  T+Y+  +    +K +G  S     +T   VP  P + I+     +   + L
Sbjct: 783 VNISGLQPDTRYDVQVAALTRKGDGARSIPVSVKTPGGVPSRPSLIIKTISREDPIEMQL 842

Query: 751 KWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQI 810
            W+ P      G I GY +    ++    K +     +VH     I      GV Y  ++
Sbjct: 843 DWTRPTQTY--GQILGYRIRYGIINQTL-KEVFLEGDSVHSYR--IKDLEERGVDYEFRV 897

Query: 811 AAETIIGLGPFSQKVYFNIDSRSVG 835
           A +  +G G    + +F+ +    G
Sbjct: 898 AGKNEVGFGQEQVRNWFSQEGAPTG 922


>UniRef50_Q4SPP8 Cluster: Chromosome 16 SCAF14537, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 16
           SCAF14537, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 590

 Score =  118 bits (284), Expect = 1e-24
 Identities = 91/319 (28%), Positives = 145/319 (45%), Gaps = 20/319 (6%)

Query: 24  ARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTH---RSILPAGGLFFLRATHGRVHSDA 80
           A+     ++C+A G+P+P+I W     + ++  +   R  +   G   +R       +D 
Sbjct: 219 AKFSRKLIDCKAEGNPTPSITWIMPDNIFLTVPYFGSRINVHRNGTLEIRNVR---PTDT 275

Query: 81  GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ--SAQGDTVVLECLPPRGSPEP 138
             + C A N  G A          +LR      P +++  S  G T++L C    G P P
Sbjct: 276 AEFICLARNDGGEAVMVVQLEVTGLLRRPIFKNPFNERIVSQIGKTIILNC-SADGHPSP 334

Query: 139 NVYWK-KNGQTLLFDGD--SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195
            + W   NG       +  S  H+   G+LVI+  ++ DAG Y+C ARN  G  E  I  
Sbjct: 335 QIVWTFPNGTRFSNKAEHGSHFHIRKDGSLVIRPGKE-DAGNYRCGARNYMGYIEKLI-I 392

Query: 196 LKIHIKPYLITGPEDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSAG---GGNMPLGRVKV 251
           L++  KPY++T P  V+ + +G  +   C   G P P + W    G        LGR ++
Sbjct: 393 LEVGQKPYIMTRPRGVIRSVSGEPLFLHCLSDGSPTPKIYWTIPGGHTLSHPQILGRHQL 452

Query: 252 LDDGSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSP-NSVNVESGNV 309
           L++G+L +++  L D G Y C A N  G AV     + V  PP I + P  +V    G  
Sbjct: 453 LENGTLVVEHTTLHDRGNYICRARNDAGEAVIIVPVVIVAYPPRITIGPLPNVKATRGTP 512

Query: 310 ARFTCTATGRPEPTMFWSV 328
            + +C A G P+P + W +
Sbjct: 513 LQLSCAAIGIPKPEITWEL 531



 Score =  113 bits (273), Expect = 2e-23
 Identities = 123/487 (25%), Positives = 199/487 (40%), Gaps = 49/487 (10%)

Query: 18  PLDVTVARHQPA---TLNCRAGGSPSPAIRWY-KGGVLVVSDTHRSILPAGGLFFLRATH 73
           P   T AR +P      +C A G P P I W      ++ +   R ++   G   +R   
Sbjct: 112 PPSQTYARVKPGGSIRFDCEAVGEPKPKIFWMLPTNDVIAASNERYLVHVNGSLDIRDI- 170

Query: 74  GRVHSDAGVYWCEATNSYGTARS---RNATLHVAVLREEFRLEPESKQ-SAQGDTVVLEC 129
            RV SD G Y C A N  G  R     +   +  V+    +     K  +A+    +++C
Sbjct: 171 -RV-SDTGEYVCMARNPAGENRKVYKLDIDGNPPVINGHRQNRTVIKDVAAKFSRKLIDC 228

Query: 130 LPPRGSPEPNVYWKKNGQTLL---FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
               G+P P++ W       L   + G SR+++   G L I++ R TD   + C+ARN  
Sbjct: 229 -KAEGNPTPSITWIMPDNIFLTVPYFG-SRINVHRNGTLEIRNVRPTDTAEFICLARNDG 286

Query: 187 GTRESAIATLKIHIKPYL----ITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
           G    A+  +++ +   L       P  E +V+Q G ++   C   G P P ++W    G
Sbjct: 287 G---EAVMVVQLEVTGLLRRPIFKNPFNERIVSQIGKTIILNCSADGHPSPQIVWTFPNG 343

Query: 241 ---GGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
                    G    +  DGSL +      D G Y C A N +G +     L V   P I 
Sbjct: 344 TRFSNKAEHGSHFHIRKDGSLVI-RPGKEDAGNYRCGARNYMGYIEKLIILEVGQKPYIM 402

Query: 297 LSPNSV-NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
             P  V    SG      C + G P P ++W++ G  T+  P +         + +  T 
Sbjct: 403 TRPRGVIRSVSGEPLFLHCLSDGSPTPKIYWTIPGGHTLSHPQI----LGRHQLLENGT- 457

Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
           L +  T  +D R   +C A N AG + +   + + +     PP IT GP       +   
Sbjct: 458 LVVEHTTLHD-RGNYICRARNDAGEAVIIVPVVIVAY----PPRITIGPLPNVKATRGTP 512

Query: 416 V-FPCTAICTPEPIIAWYFEGEALIQNHRRN-------VTNDGTLVLKDLDKSDSGTYTC 467
           +   C AI  P+P I W     +++ + ++        +   GTL+++    SD+G Y C
Sbjct: 513 LQLSCAAIGIPKPEITWELPDRSVLSSTQQGRPTGGELLHPQGTLIIQRPSVSDTGRYKC 572

Query: 468 VASSRHG 474
           +A +  G
Sbjct: 573 LAKNYLG 579



 Score =  113 bits (272), Expect = 3e-23
 Identities = 138/560 (24%), Positives = 221/560 (39%), Gaps = 59/560 (10%)

Query: 31  LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF--FLRATHGRVH------SDAGV 82
           ++C+A G+P P I W      +VS   ++ + +GG    +    +G ++      S+ G 
Sbjct: 24  VDCKASGAPKPEISWGLPDGTMVSSAFQADVSSGGQAQRYTLFDNGTLYLNQVSISEEGD 83

Query: 83  YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GDTVVLECLPPRGSPEPN 139
           Y C A N  G       T+H++V+     + P S+  A+   G ++  +C    G P+P 
Sbjct: 84  YICYAENHLG---KDEMTVHISVMTVTPVIHPPSQTYARVKPGGSIRFDC-EAVGEPKPK 139

Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
           ++W      ++   + R  +   G+L I+D R +D G Y C+ARN AG     +  L I 
Sbjct: 140 IFWMLPTNDVIAASNERYLVHVNGSLDIRDIRVSDTGEYVCMARNPAGENRK-VYKLDID 198

Query: 200 IKPYLITGP-------EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG-GGNMPL--GRV 249
             P +I G        +DV A+  S     C+  G+P P + W         +P    R+
Sbjct: 199 GNPPVINGHRQNRTVIKDVAAKF-SRKLIDCKAEGNPTPSITWIMPDNIFLTVPYFGSRI 257

Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD----PPSINLSPNSVNVE 305
            V  +G+L + NV   D  E+ C A N  G       L V      P   N     +  +
Sbjct: 258 NVHRNGTLEIRNVRPTDTAEFICLARNDGGEAVMVVQLEVTGLLRRPIFKNPFNERIVSQ 317

Query: 306 SGNVARFTCTATGRPEPTMFWSV-EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
            G      C+A G P P + W+   G R   F   +    H     DG  V+     D  
Sbjct: 318 IGKTIILNCSADGHPSPQIVWTFPNGTR---FSNKAEHGSHFHIRKDGSLVIRPGKEDAG 374

Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF-PCTAIC 423
           + R    C A NY G  ++  KL +     +  P I   P      +    +F  C +  
Sbjct: 375 NYR----CGARNYMG--YIE-KLIILEVGQK--PYIMTRPRGVIRSVSGEPLFLHCLSDG 425

Query: 424 TPEPIIAWYFEGEALIQN----HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK-YVW 478
           +P P I W   G   + +     R  +  +GTLV++     D G Y C A +  G+  + 
Sbjct: 426 SPTPKIYWTIPGGHTLSHPQILGRHQLLENGTLVVEHTTLHDRGNYICRARNDAGEAVII 485

Query: 479 SGALLVDSPIN------PNIHFFRAADVS---SLPGPPTKPITHNVTDTSVTLSWSQNNK 529
              ++V  P        PN+   R   +    +  G P   IT  + D SV  S  Q   
Sbjct: 486 VPVVIVAYPPRITIGPLPNVKATRGTPLQLSCAAIGIPKPEITWELPDRSVLSSTQQGRP 545

Query: 530 IGSSSILGYQVEVFSRETLS 549
            G   +      +  R ++S
Sbjct: 546 TGGELLHPQGTLIIQRPSVS 565



 Score = 94.3 bits (224), Expect = 2e-17
 Identities = 79/285 (27%), Positives = 128/285 (44%), Gaps = 36/285 (12%)

Query: 216 GSSVTFQCRVGGDPLPDVLWR-------RSAGGGNMPLG----RVKVLDDGSLRLDNVIL 264
           G+ V   C+  G P P++ W         SA   ++  G    R  + D+G+L L+ V +
Sbjct: 19  GNGVKVDCKASGAPKPEISWGLPDGTMVSSAFQADVSSGGQAQRYTLFDNGTLYLNQVSI 78

Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS--VNVESGNVARFTCTATGRPEP 322
           ++EG+Y C AEN +G    + +++V     +   P+     V+ G   RF C A G P+P
Sbjct: 79  SEEGDYICYAENHLGKDEMTVHISVMTVTPVIHPPSQTYARVKPGGSIRFDCEAVGEPKP 138

Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
            +FW +  N  +I     R   H     D +  + ++DT +       VC A N AG + 
Sbjct: 139 KIFWMLPTN-DVIAASNERYLVHVNGSLD-IRDIRVSDTGE------YVCMARNPAGENR 190

Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA------VFPCTAICTPEPIIAWYFEGE 436
              KL    D D  PP+I     N+T+ IK +A      +  C A   P P I W     
Sbjct: 191 KVYKL----DIDGNPPVINGHRQNRTV-IKDVAAKFSRKLIDCKAEGNPTPSITWIMPDN 245

Query: 437 ALIQ----NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
             +       R NV  +GTL ++++  +D+  + C+A +  G+ V
Sbjct: 246 IFLTVPYFGSRINVHRNGTLEIRNVRPTDTAEFICLARNDGGEAV 290



 Score = 89.4 bits (212), Expect = 5e-16
 Identities = 80/274 (29%), Positives = 111/274 (40%), Gaps = 23/274 (8%)

Query: 31  LNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRATHGRV----HSDAGVYWC 85
           LNC A G PSP I W +  G    +         G  F +R     V      DAG Y C
Sbjct: 324 LNCSADGHPSPQIVWTFPNGTRFSNKAEH-----GSHFHIRKDGSLVIRPGKEDAGNYRC 378

Query: 86  EATNSYGTARSRNATLHVAVLREEFRLEPESK-QSAQGDTVVLECLPPRGSPEPNVYWK- 143
            A N  G    +   L V   +      P    +S  G+ + L CL   GSP P +YW  
Sbjct: 379 GARNYMGYIE-KLIILEVGQ-KPYIMTRPRGVIRSVSGEPLFLHCLSD-GSPTPKIYWTI 435

Query: 144 KNGQTLLFDGDSRMH-LVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKP 202
             G TL        H L++ G LV++     D G Y C ARN AG     +  + +   P
Sbjct: 436 PGGHTLSHPQILGRHQLLENGTLVVEHTTLHDRGNYICRARNDAGEAVIIVPVVIVAYPP 495

Query: 203 YLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRR------SAGGGNMPLGRVKVLDDG 255
            +  GP  +V A  G+ +   C   G P P++ W        S+     P G   +   G
Sbjct: 496 RITIGPLPNVKATRGTPLQLSCAAIGIPKPEITWELPDRSVLSSTQQGRPTGGELLHPQG 555

Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
           +L +    ++D G Y C A+N +G  S   Y+ V
Sbjct: 556 TLIIQRPSVSDTGRYKCLAKNYLGIDSKVTYVRV 589



 Score = 60.5 bits (140), Expect = 3e-07
 Identities = 57/191 (29%), Positives = 86/191 (45%), Gaps = 19/191 (9%)

Query: 9   GEAPYIIEQPLDVTVA-RHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
           G+ PYI+ +P  V  +   +P  L+C + GSP+P I W   G   +S  H  IL    L 
Sbjct: 396 GQKPYIMTRPRGVIRSVSGEPLFLHCLSDGSPTPKIYWTIPGGHTLS--HPQILGRHQLL 453

Query: 68  ---FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGD 123
               L   H  +H D G Y C A N  G A      + VA       + P  + ++ +G 
Sbjct: 454 ENGTLVVEHTTLH-DRGNYICRARNDAGEAVIIVPVVIVAY-PPRITIGPLPNVKATRGT 511

Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFD-------GDSRMHLVDGGNLVIQDARQTDAG 176
            + L C    G P+P + W+   +++L         G   +H    G L+IQ    +D G
Sbjct: 512 PLQLSCAAI-GIPKPEITWELPDRSVLSSTQQGRPTGGELLH--PQGTLIIQRPSVSDTG 568

Query: 177 RYQCIARNAAG 187
           RY+C+A+N  G
Sbjct: 569 RYKCLAKNYLG 579



 Score = 53.2 bits (122), Expect = 4e-05
 Identities = 48/181 (26%), Positives = 81/181 (44%), Gaps = 17/181 (9%)

Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRD-----KYHATAVFDGVTVLTI 358
           V  GN  +  C A+G P+P + W +  + T++      D     +     +FD  T L +
Sbjct: 16  VTYGNGVKVDCKASGAPKPEISWGLP-DGTMVSSAFQADVSSGGQAQRYTLFDNGT-LYL 73

Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK--SMAV 416
           N    ++     +C A N+ G    + ++TV        P+I + PS     +K      
Sbjct: 74  NQVSISE-EGDYICYAENHLG----KDEMTVHISVMTVTPVI-HPPSQTYARVKPGGSIR 127

Query: 417 FPCTAICTPEPIIAWYFEGEALI--QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
           F C A+  P+P I W      +I   N R  V  +G+L ++D+  SD+G Y C+A +  G
Sbjct: 128 FDCEAVGEPKPKIFWMLPTNDVIAASNERYLVHVNGSLDIRDIRVSDTGEYVCMARNPAG 187

Query: 475 K 475
           +
Sbjct: 188 E 188


>UniRef50_Q94155 Cluster: Unc-40 protein; n=2; Caenorhabditis|Rep:
           Unc-40 protein - Caenorhabditis elegans
          Length = 1415

 Score =  118 bits (284), Expect = 1e-24
 Identities = 175/745 (23%), Positives = 293/745 (39%), Gaps = 91/745 (12%)

Query: 109 EFRLEPESKQSA-QGDTVVLEC----LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG 163
           +F +EP    +  +  + +LEC       R   +  + WK++G  L     SR+ ++  G
Sbjct: 42  QFVMEPRRNVTVMESSSHLLECSYVLAHERLVHDVRIEWKRDGVLLSERTSSRIKVMSNG 101

Query: 164 NLVIQDARQTDAGRYQC---IARNAAGTRE-----SAIATLKI-HIKPYLITGPEDVVAQ 214
           +L I+     + G YQC   +   +  T +     S  ATL++  +  + +   +  +A+
Sbjct: 102 SLWIESVSSAEEGTYQCAVHVTTKSDQTSDTWTFLSRKATLRLADLAKFELQAIDRTLAK 161

Query: 215 TGSSVTFQCRVGGDPLPDVLWRRS----AGGGNMPLGRVKVLDDGSLRLDNVILADEGEY 270
            G    F C +   P P  +W  +      GG   +  V      +L + +     EG Y
Sbjct: 162 -GQPTAFHCLINSKPTPTAVWLHNDEPIVNGGEYHILPV----SNTLEISSTQSRHEGTY 216

Query: 271 SCEAENS-VGAVSASGYLTVYDPPSIN-----LSPNSVNVESGNVARFTCTATGRPEPTM 324
            C  E +     S +  LTV      N      +P    VE G+     C       P +
Sbjct: 217 RCTVEGAGKRRSSQTARLTVTTETVSNELVFITTPRLQVVEQGDEFLLECLVASLIRPQV 276

Query: 325 FWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR 384
            W ++ +R II  G+   +   +++   V+  +I DT          C A N    S  R
Sbjct: 277 RW-LKDSRQIIVDGVRIRRVGVSSIL--VSRASIEDT------GLYTCRASN-NDDSIDR 326

Query: 385 GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC-TAICTPEPIIAWYFEGEALIQNHR 443
                 S + R PP IT  P+ +     +     C TA   PE  + WY  GEA+I    
Sbjct: 327 ----AVSVEVRAPPRITTRPTTKVAVETADVELECGTAAARPEARVNWYKNGEAII-GSE 381

Query: 444 RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSL 503
             V     L +  + ++D   Y C+A +  G    S  LLVD+P + ++     A  S +
Sbjct: 382 YFVIEPNRLRILGVVRADQAIYQCIAENDVGSEQASAQLLVDAPDSSSV-----AASSGV 436

Query: 504 PGPPTKPITHNVTDTS---VTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGW 560
           P   + P+    T +    + + W    +  + +I+ Y   +F ++ L       NS   
Sbjct: 437 PMTSSAPLGLRSTSSGSRFINVEWDPPVQ-RNGNIMRY--HIFYKDNLIDRERMINS--- 490

Query: 561 VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGV 620
                    T   + SL P   Y+  V  EN  G+      SDS+ V  +      G   
Sbjct: 491 -------SSTSATLTSLQPSTMYLIRVTAENEAGM---GKFSDSLKVTTNKEQAVPGKVA 540

Query: 621 SNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEM 680
           S +T        D     I  +P       L ++I  FY  +       PL+    + E 
Sbjct: 541 SLTTTATGPETID-----IRWSPPSGGQPALRYKI--FYSHD-------PLE----KNEK 582

Query: 681 KTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEM 740
           +T++ +   + + +  + KYT Y+  +        G  S++   +T  D P  PP+NI+ 
Sbjct: 583 ETLI-TTSTTHYTLHGMDKYTGYQIRIEAEGSNGSGLSSDTVKVRTQSDEPSAPPVNIQA 641

Query: 741 FILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNL 800
              ++T+V + W  PE +  NG ITGY +        A  + + I+ T  + T   M NL
Sbjct: 642 EADSSTSVRVSWDEPEEESVNGEITGYRLKYKTKARGAKGNTLVIDATAREYT---MGNL 698

Query: 801 TSGVSYSVQIAAETIIGLGPFSQKV 825
                Y +++A     G GPFS  V
Sbjct: 699 EPNTQYLIRMAVVNHNGTGPFSDWV 723



 Score =  101 bits (243), Expect = 9e-20
 Identities = 80/291 (27%), Positives = 129/291 (44%), Gaps = 15/291 (5%)

Query: 17  QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV 76
           Q +D T+A+ QP   +C     P+P   W      +V+     ILP      + +T  R 
Sbjct: 153 QAIDRTLAKGQPTAFHCLINSKPTPTAVWLHNDEPIVNGGEYHILPVSNTLEISSTQSR- 211

Query: 77  HSDAGVYWC--EATNSYGTARSRNATLHVAVLREE--FRLEPESKQSAQGDTVVLECLPP 132
           H   G Y C  E      ++++   T+    +  E  F   P  +   QGD  +LECL  
Sbjct: 212 HE--GTYRCTVEGAGKRRSSQTARLTVTTETVSNELVFITTPRLQVVEQGDEFLLECLVA 269

Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
                P V W K+ + ++ DG  R+  V   ++++  A   D G Y C A N   + + A
Sbjct: 270 -SLIRPQVRWLKDSRQIIVDG-VRIRRVGVSSILVSRASIEDTGLYTCRASNNDDSIDRA 327

Query: 193 IATLKIHIKPYLITGPEDVVAQTGSSVTFQC-RVGGDPLPDVLWRRSAGGGNMPLG-RVK 250
           ++ +++   P + T P   VA   + V  +C      P   V W ++   G   +G    
Sbjct: 328 VS-VEVRAPPRITTRPTTKVAVETADVELECGTAAARPEARVNWYKN---GEAIIGSEYF 383

Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
           V++   LR+  V+ AD+  Y C AEN VG+  AS  L V  P S +++ +S
Sbjct: 384 VIEPNRLRILGVVRADQAIYQCIAENDVGSEQASAQLLVDAPDSSSVAASS 434



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 46/169 (27%), Positives = 67/169 (39%), Gaps = 12/169 (7%)

Query: 694  ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVA---QTLDDVPDGPPINIEMFILNTTTVH- 749
            +  LR  T+YEF +        G+ S   +A   +TL   P   P ++ +    +   H 
Sbjct: 906  VEGLRPATEYEFAVRAVASN--GQLSTWSMATRNRTLAAPPSSAPRDLTVLPAESGDPHS 963

Query: 750  --LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYS 807
              L W PP+    NG I  Y V        A+K    IN       S  ++NL    +Y 
Sbjct: 964  SSLHWQPPKYS--NGEIEEYLVFYTDRASLADKDWT-INYVAGDKLSHQVSNLLPKANYF 1020

Query: 808  VQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFV 856
             +I A    G GPFS  V +     ++ L    R+   G  S  +GD V
Sbjct: 1021 FKIQARNEKGHGPFSSVVGYTPSGGAI-LSGKDRHNARGHGSAASGDTV 1068


>UniRef50_A7RNP0 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 1874

 Score =  117 bits (282), Expect = 2e-24
 Identities = 85/291 (29%), Positives = 130/291 (44%), Gaps = 30/291 (10%)

Query: 33  CRAGGSPSPAIRWYKGGVLVVSDTHRSI-LPAGGLFFLRATHGRVHSDAGVYWCEATNSY 91
           C   GSP P + WYK G ++ +   +   +P GGL  +     ++H     Y CEA N  
Sbjct: 22  CNVTGSPMPTLTWYKNGSVIRNSRIQIFTMPYGGLIRIGPLRAKIHK--ATYECEADNGV 79

Query: 92  GTARSRNATL--HVAVLRE----EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
           G     ++TL  H A  +          P  KQ   GD V   C    G+P PN+ W K+
Sbjct: 80  GPPLRDSSTLIVHTASTKPAGFPRIAKHPSFKQRRSGDDVTFTCAAV-GTPTPNITWFKD 138

Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG---TRESAIATLKIHI-- 200
              ++ +      L DG  L I D R++D G+Y C+ARNA G   + ++  A L I++  
Sbjct: 139 RLPIVLNDPRVSVLSDGRKLRITDLRESDNGKYSCVARNALGMVFSSQAMPARLFIYLTL 198

Query: 201 -----KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
                KP     P+D      + V  +C   G P P ++W      G+   G+     +G
Sbjct: 199 SVVRSKPEFTLRPQDKTVDPDTDVELKCSARGSPTPSIVWEVD---GSRISGQ-----NG 250

Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
            L +  +     G YSC A++++G V A  Y+TV   P     PN+ ++ S
Sbjct: 251 ELIIRGI--QRSGNYSCIADSNMGRVQAYAYVTVRLLPFAPSRPNAASITS 299



 Score =  101 bits (241), Expect = 2e-19
 Identities = 153/641 (23%), Positives = 254/641 (39%), Gaps = 100/641 (15%)

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD---DGSLR 258
           P +   P+D    T   V   C V G P+P + W ++  G  +   R+++      G +R
Sbjct: 1   PTVTLTPKDFAGVTRGFVYMICNVTGSPMPTLTWYKN--GSVIRNSRIQIFTMPYGGLIR 58

Query: 259 LDNV-ILADEGEYSCEAENSVG-AVSASGYLTVYDP-------PSINLSPNSVNVESGNV 309
           +  +     +  Y CEA+N VG  +  S  L V+         P I   P+     SG+ 
Sbjct: 59  IGPLRAKIHKATYECEADNGVGPPLRDSSTLIVHTASTKPAGFPRIAKHPSFKQRRSGDD 118

Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
             FTC A G P P + W  +       P +  D    + + DG   L I D  ++D+   
Sbjct: 119 VTFTCAAVGTPTPNITWFKDR-----LPIVLNDP-RVSVLSDG-RKLRITDLRESDN-GK 170

Query: 370 IVCSAVNYAGSSF------VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
             C A N  G  F       R  + +T    R  P  T  P ++T+   +     C+A  
Sbjct: 171 YSCVARNALGMVFSSQAMPARLFIYLTLSVVRSKPEFTLRPQDKTVDPDTDVELKCSARG 230

Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
           +P P I W  +G        R    +G L+++ + +  SG Y+C+A S  G+        
Sbjct: 231 SPTPSIVWEVDGS-------RISGQNGELIIRGIQR--SGNYSCIADSNMGR-------- 273

Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543
                   +  +    V  LP  P++P   ++T  ++ ++W      G+  +  Y+V+  
Sbjct: 274 --------VQAYAYVTVRLLPFAPSRPNAASITSDAIKITWHPR---GAHVVTSYEVQY- 321

Query: 544 SRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
               L G         W  I         VV  L P  +Y F V   NS G S PS +++
Sbjct: 322 ---RLKGKTE------WQEITNVRGMQSLVVSGLRPFSSYEFRVFAVNSLGRSRPSLMAE 372

Query: 604 SVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMW--EILNFYYL 661
             T     +    G+   N                IEA  +   + K  W   I     +
Sbjct: 373 YTT-----SETKPGSAPRN----------------IEAMGVSDTSFKAGWLPPISANGRI 411

Query: 662 EGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNS 721
            G  +Y+  LD   +E   +    ++  +   +T L + T + F ++ +    +G  S  
Sbjct: 412 RGYRLYY-SLD--LLEDISQWRFMASSTNSTTVTGLTRQTTHFFRILAYNIAGDGPLSEV 468

Query: 722 RVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKS 781
              +T   VP G P ++++ +L++T + + WSPP     +GI  GY+V  N     + + 
Sbjct: 469 VAVKTQKGVP-GQPRSVQLSVLSSTAIRVTWSPPRYP-GDGIF-GYDVYYN----KSKQD 521

Query: 782 MVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFS 822
           M  +       T  IM  LT    Y V +AA++  G+GP S
Sbjct: 522 MDTVIGAFQMNTKEIM-GLTPYTVYKVAVAAKSDKGVGPMS 561



 Score = 89.4 bits (212), Expect = 5e-16
 Identities = 66/219 (30%), Positives = 95/219 (43%), Gaps = 20/219 (9%)

Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR-QTDAGRYQCIARNAAGTRESA 192
           GSP P + W KNG  +         +  GG + I   R +     Y+C A N  G     
Sbjct: 26  GSPMPTLTWYKNGSVIRNSRIQIFTMPYGGLIRIGPLRAKIHKATYECEADNGVGPPLRD 85

Query: 193 IATLKIHIK-------PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
            +TL +H         P +   P     ++G  VTF C   G P P++ W +      + 
Sbjct: 86  SSTLIVHTASTKPAGFPRIAKHPSFKQRRSGDDVTFTCAAVGTPTPNITWFKDRLPIVLN 145

Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASG--------YLT---VYDPP 293
             RV VL DG  LR+ ++  +D G+YSC A N++G V +S         YLT   V   P
Sbjct: 146 DPRVSVLSDGRKLRITDLRESDNGKYSCVARNALGMVFSSQAMPARLFIYLTLSVVRSKP 205

Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332
              L P    V+        C+A G P P++ W V+G+R
Sbjct: 206 EFTLRPQDKTVDPDTDVELKCSARGSPTPSIVWEVDGSR 244



 Score = 70.9 bits (166), Expect = 2e-10
 Identities = 61/189 (32%), Positives = 90/189 (47%), Gaps = 26/189 (13%)

Query: 30  TLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
           T  C A G+P+P I W+K  + +V++D   S+L  G    LR T  R  SD G Y C A 
Sbjct: 120 TFTCAAVGTPTPNITWFKDRLPIVLNDPRVSVLSDGRK--LRITDLR-ESDNGKYSCVAR 176

Query: 89  NSYGTARSRNA---------TLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
           N+ G   S  A         TL V   + EF L P+ K       V L+C   RGSP P+
Sbjct: 177 NALGMVFSSQAMPARLFIYLTLSVVRSKPEFTLRPQDKTVDPDTDVELKC-SARGSPTPS 235

Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
           + W+ +G  +   G +       G L+I+  ++  +G Y CIA +  G R  A A + + 
Sbjct: 236 IVWEVDGSRI--SGQN-------GELIIRGIQR--SGNYSCIADSNMG-RVQAYAYVTVR 283

Query: 200 IKPYLITGP 208
           + P+  + P
Sbjct: 284 LLPFAPSRP 292



 Score = 66.9 bits (156), Expect = 3e-09
 Identities = 47/186 (25%), Positives = 86/186 (46%), Gaps = 6/186 (3%)

Query: 639 IEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLR 698
           I+    DS T+++ W+     +  GL  +F        +   K +      +   + +L 
Sbjct: 580 IQGRSRDSTTLEISWDPPRPEHRNGLITHFTIKYRAKGQRGAKYLTVDATKTSVVLHNLD 639

Query: 699 KYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQ 758
           K+T Y  ++    K+ +G  S+     T +DVP+G P ++ + + N+TT+ +KW+PP  +
Sbjct: 640 KFTNYFIWVQASTKQGDGPFSDKHTVSTAEDVPNGAPRDVRIRVHNSTTMTVKWNPPTTK 699

Query: 759 LQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATS-----LIMTNLTSGVSYSVQIAAE 813
            Q+G I GY V    +D   N+           + S     + +T L    +Y +++AA 
Sbjct: 700 -QDGKILGYMVFYTRVDDQGNQLRPPAQPESKDSMSEENHKVHLTGLAPETTYQIEVAAY 758

Query: 814 TIIGLG 819
           TI G G
Sbjct: 759 TIKGDG 764



 Score = 64.1 bits (149), Expect = 2e-08
 Identities = 49/186 (26%), Positives = 86/186 (46%), Gaps = 7/186 (3%)

Query: 639 IEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLR 698
           ++ + + S  I++ W     Y  +G+F Y    +    + +M T++ +  ++  EI  L 
Sbjct: 484 VQLSVLSSTAIRVTWSPPR-YPGDGIFGYDVYYNKS--KQDMDTVIGAFQMNTKEIMGLT 540

Query: 699 KYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQ 758
            YT Y+  +     K  G  S    A+T +D P   P NI+    ++TT+ + W PP  +
Sbjct: 541 PYTVYKVAVAAKSDKGVGPMSFVLTARTDEDRPSDAPQNIQGRSRDSTTLEISWDPPRPE 600

Query: 759 LQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGL 818
            +NG+IT + +          K +    T     TS+++ NL    +Y + + A T  G 
Sbjct: 601 HRNGLITHFTIKYRAKGQRGAKYLTVDAT----KTSVVLHNLDKFTNYFIWVQASTKQGD 656

Query: 819 GPFSQK 824
           GPFS K
Sbjct: 657 GPFSDK 662



 Score = 62.9 bits (146), Expect = 5e-08
 Identities = 41/147 (27%), Positives = 69/147 (46%), Gaps = 7/147 (4%)

Query: 679 EMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINI 738
           +MK I   +  +  +  SL     Y  F +    K    P  SR  +     P GPP+N+
Sbjct: 831 KMKEIKFKSHTTKQKFQSLANGIWY-LFNVSLRTKAGWSPETSRWIEIPPGPPSGPPLNV 889

Query: 739 EMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANK--SMVAINTTVHQATSLI 796
               +++T+V + WS P++  + G I GY+V+ N    PANK   +   N T      ++
Sbjct: 890 RAVAVSSTSVEVTWSAPDIWNRGGPILGYSVMYN----PANKRGDVTVKNVTSPNIFKVV 945

Query: 797 MTNLTSGVSYSVQIAAETIIGLGPFSQ 823
           +  L     Y V++ A  ++G+GP S+
Sbjct: 946 LKRLKKFREYEVRVRAIGMLGMGPASE 972



 Score = 52.8 bits (121), Expect = 5e-05
 Identities = 51/220 (23%), Positives = 90/220 (40%), Gaps = 15/220 (6%)

Query: 641 ATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKY 700
           A  I S  IK+ W     + +    + +R    +  + E + I +   +    ++ LR +
Sbjct: 294 AASITSDAIKITWHPRGAHVVTSYEVQYR----LKGKTEWQEITNVRGMQSLVVSGLRPF 349

Query: 701 TKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQ 760
           + YEF +         +PS      T +  P   P NIE   ++ T+    W PP     
Sbjct: 350 SSYEFRVFAVNSLGRSRPSLMAEYTTSETKPGSAPRNIEAMGVSDTSFKAGWLPP--ISA 407

Query: 761 NGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGP 820
           NG I GY +  + LD+  + S      +   +T+  +T LT   ++  +I A  I G GP
Sbjct: 408 NGRIRGYRLYYS-LDLLEDISQWRFMASSTNSTT--VTGLTRQTTHFFRILAYNIAGDGP 464

Query: 821 FSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETW 860
            S+ V         G       P + ++S+++   +  TW
Sbjct: 465 LSEVVAVKTQKGVPG------QPRSVQLSVLSSTAIRVTW 498


>UniRef50_UPI00015A4156 Cluster: Neogenin precursor.; n=1; Danio
           rerio|Rep: Neogenin precursor. - Danio rerio
          Length = 1088

 Score =  117 bits (281), Expect = 2e-24
 Identities = 84/285 (29%), Positives = 128/285 (44%), Gaps = 13/285 (4%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P  + QP  V+V       L+C       P  RW +    V  D+    LP+G L    A
Sbjct: 7   PRFLSQPEGVSVRSGGTEMLSCEVTEELVPFTRWDRDARPVELDSRVIQLPSGALVISNA 66

Query: 72  THGRVHSDAGVYWCEATNSYGTARSRNATLHV-----AVLREEFRLEPESKQSAQGDTVV 126
           +     +DAG+Y C          +  A L V     A  + E    P +     G++V+
Sbjct: 67  SQ----ADAGLYRCTIDGLGPPKTTEEAELQVVTDSGAGEKLETLQGPVAVAKVVGESVL 122

Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
           L C+  +G P P + W  N Q +  +   R  ++ GG+L I +  + DAG Y C A +  
Sbjct: 123 LPCVM-KGHPIPAIRWTFNDQPIE-EAHERFSVIGGGSLQIVNLTEEDAGIYVCQADSGN 180

Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
            T E   A L +H+ P  +T P +  AQ    + F+C V G P P V W +  G   +P 
Sbjct: 181 MTSEIQ-AELTVHVPPRFLTRPSNTYAQESMDIIFECDVTGSPPPTVKWMKD-GDTVIPS 238

Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
              +++   +L++  ++ +DEG Y C AEN  G V AS  L + D
Sbjct: 239 DYFRIVKQHNLQVLGLVKSDEGFYQCLAENDAGNVQASAQLIILD 283



 Score = 90.6 bits (215), Expect = 2e-16
 Identities = 64/231 (27%), Positives = 98/231 (42%), Gaps = 9/231 (3%)

Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
           F  +PE      G T +L C        P   W ++ + +  + DSR+  +  G LVI +
Sbjct: 9   FLSQPEGVSVRSGGTEMLSCEVTE-ELVPFTRWDRDARPV--ELDSRVIQLPSGALVISN 65

Query: 170 ARQTDAGRYQCIARNAAGTRESAIATLKIHI------KPYLITGPEDVVAQTGSSVTFQC 223
           A Q DAG Y+C        + +  A L++        K   + GP  V    G SV   C
Sbjct: 66  ASQADAGLYRCTIDGLGPPKTTEEAELQVVTDSGAGEKLETLQGPVAVAKVVGESVLLPC 125

Query: 224 RVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSA 283
            + G P+P + W  +         R  V+  GSL++ N+   D G Y C+A++       
Sbjct: 126 VMKGHPIPAIRWTFNDQPIEEAHERFSVIGGGSLQIVNLTEEDAGIYVCQADSGNMTSEI 185

Query: 284 SGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334
              LTV+ PP     P++   +      F C  TG P PT+ W  +G+  I
Sbjct: 186 QAELTVHVPPRFLTRPSNTYAQESMDIIFECDVTGSPPPTVKWMKDGDTVI 236



 Score = 74.1 bits (174), Expect = 2e-11
 Identities = 53/195 (27%), Positives = 88/195 (45%), Gaps = 12/195 (6%)

Query: 8   SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPAGGL 66
           +GE    ++ P+ V     +   L C   G P PAIRW +    +  +    S++  G L
Sbjct: 100 AGEKLETLQGPVAVAKVVGESVLLPCVMKGHPIPAIRWTFNDQPIEEAHERFSVIGGGSL 159

Query: 67  FFLRATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTV 125
             +  T      DAG+Y C+A +   T+  +   T+HV      F   P +  + +   +
Sbjct: 160 QIVNLTE----EDAGIYVCQADSGNMTSEIQAELTVHVP---PRFLTRPSNTYAQESMDI 212

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
           + EC    GSP P V W K+G T++        +V   NL +    ++D G YQC+A N 
Sbjct: 213 IFEC-DVTGSPPPTVKWMKDGDTVI--PSDYFRIVKQHNLQVLGLVKSDEGFYQCLAEND 269

Query: 186 AGTRESAIATLKIHI 200
           AG  +++   + + I
Sbjct: 270 AGNVQASAQLIILDI 284



 Score = 71.3 bits (167), Expect = 1e-10
 Identities = 68/290 (23%), Positives = 111/290 (38%), Gaps = 22/290 (7%)

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDN 261
           P  ++ PE V  ++G +    C V  + +P   W R A    +   RV  L  G+L + N
Sbjct: 7   PRFLSQPEGVSVRSGGTEMLSCEVTEELVPFTRWDRDARPVELD-SRVIQLPSGALVISN 65

Query: 262 VILADEGEYSCEAEN-SVGAVSASGYLTVYDPPSIN------LSPNSVNVESGNVARFTC 314
              AD G Y C  +       +    L V               P +V    G      C
Sbjct: 66  ASQADAGLYRCTIDGLGPPKTTEEAELQVVTDSGAGEKLETLQGPVAVAKVVGESVLLPC 125

Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
              G P P + W+              + +   +V  G ++  +N T+++      VC A
Sbjct: 126 VMKGHPIPAIRWTFNDQPI-------EEAHERFSVIGGGSLQIVNLTEED--AGIYVCQA 176

Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFE 434
            +   +S ++ +LTV      PP  +T  PSN         +F C    +P P + W  +
Sbjct: 177 DSGNMTSEIQAELTVHV----PPRFLTR-PSNTYAQESMDIIFECDVTGSPPPTVKWMKD 231

Query: 435 GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
           G+ +I +    +     L +  L KSD G Y C+A +  G    S  L++
Sbjct: 232 GDTVIPSDYFRIVKQHNLQVLGLVKSDEGFYQCLAENDAGNVQASAQLII 281



 Score = 68.9 bits (161), Expect = 8e-10
 Identities = 31/84 (36%), Positives = 51/84 (60%), Gaps = 2/84 (2%)

Query: 688 DVSG--FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNT 745
           DVSG  + +TSL+K+T+Y F ++ + K   G  +     +TL DVP   P N+ + +LN+
Sbjct: 444 DVSGLSYTMTSLKKFTEYSFRVVAYNKHGPGVSTEDVTVRTLSDVPSAAPQNLTLDVLNS 503

Query: 746 TTVHLKWSPPELQLQNGIITGYNV 769
           T++ ++W PP     NG +TGY +
Sbjct: 504 TSIMVRWQPPPAGSLNGELTGYKL 527



 Score = 51.6 bits (118), Expect = 1e-04
 Identities = 55/227 (24%), Positives = 92/227 (40%), Gaps = 17/227 (7%)

Query: 612 NSLWEGTGVSNSTEYRNNILTDHIVEL----IEATPIDSKTIKLMWE----ILNFYYLEG 663
           N++ EG  + NS   R     D    L    ++A+ +   T+K+ W       N    + 
Sbjct: 670 NNMGEGVPIYNSATTRPQSAPDPTPMLPPVGVQASVLSHDTVKVSWADNSLAKNQKITDA 729

Query: 664 LFIYFRPLDNITIEYEMKTILHSNDVSGFE-ITSLRKYTKYEFFLIPFYKKFEGKPSNSR 722
            +   R   NI    + K    +N  S F  +++L+  T YEF ++    +     S + 
Sbjct: 730 RYYTIRWKTNIPANTKYKM---ANTTSLFHTVSALKPNTLYEFSVMVTKNRRSSTWSMTA 786

Query: 723 VAQTLDDVPDGPPINIEMFIL--NTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANK 780
            + T + +P   P ++ +     N   +++ W PP     NG ITGY ++    DV A  
Sbjct: 787 HSTTHESIPSSAPKDVTVISKEGNPRIININWQPPTEA--NGKITGY-IIYYSTDVNAEV 843

Query: 781 SMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYF 827
               +   V    +  +  LT   SY  +I A    G+GP S  V F
Sbjct: 844 HDWVVEPVVGNRLTHQIQGLTLDTSYFFKIQARNSKGMGPMSDAVQF 890



 Score = 39.9 bits (89), Expect = 0.41
 Identities = 27/117 (23%), Positives = 49/117 (41%), Gaps = 8/117 (6%)

Query: 674 ITIEYEMKTILHSN-DVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPD 732
           +T++Y+ +     N D S   + +L+ Y       +P Y     +P ++      D  P 
Sbjct: 642 VTLDYKQRFYSIDNLDASSHYVITLKAYNNMGEG-VPIYNSATTRPQSAP-----DPTPM 695

Query: 733 GPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNW-LDVPANKSMVAINTT 788
            PP+ ++  +L+  TV + W+   L     I       + W  ++PAN      NTT
Sbjct: 696 LPPVGVQASVLSHDTVKVSWADNSLAKNQKITDARYYTIRWKTNIPANTKYKMANTT 752


>UniRef50_Q4RRR9 Cluster: Chromosome 16 SCAF15002, whole genome
           shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 16
           SCAF15002, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 875

 Score =  117 bits (281), Expect = 2e-24
 Identities = 112/421 (26%), Positives = 174/421 (41%), Gaps = 37/421 (8%)

Query: 79  DAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPE 137
           DAGVY C ATN    A S   T+ V + ++  FR  P  ++  +GD   + C     SP 
Sbjct: 80  DAGVYKCIATNGDQQAES---TVKVKIFQKITFRNAPSPQEFTEGDIADIIC-DIESSPP 135

Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR-NAAGTRESAIATL 196
           P V WK  G+ +  D D R   +   +L I+  ++TD G Y C  R  + G  +  +  +
Sbjct: 136 PTVLWKYKGRKIQMDKDVRFKELSNNHLQIRGIKKTDEGPYTCEGRLMSRGEIDFRVIKV 195

Query: 197 KIHIKPYLITGPEDV--VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLD 253
            +++ P +     +V   A  G  V   C V G P P V W R+  G  +  G +    +
Sbjct: 196 IVNVLPTIRVWQTEVNATADVGQPVKLTCAVDGYPEPMVTWTRN--GVVLEAGEKYSFNE 253

Query: 254 DGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-------PPSINLSPNSVNVE 305
           DGS + L  V   DEGEY+C A+N  G       L V+D        P I    N+  +E
Sbjct: 254 DGSEMTLLEVAKLDEGEYTCIAKNKAGESEQELSLRVFDSVLVFAVKPKITYIINTTALE 313

Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
           +      TC A+G P PT+ WS  GN   +F     ++ H   ++  +    +  +D   
Sbjct: 314 TEEQVTLTCEASGDPTPTISWSYGGN---VF--SEGEQAHLNRIYQSLDGNVVTRSDARV 368

Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDD------RPPPIITNGPSNQTLPIKSMAVFPC 419
           S   +       AG      +  +  D+       R  P I    +  T    ++ +  C
Sbjct: 369 SSLNLKHVKYTDAGQYLCTARSAIGEDEQSAYLEVRYAPKIHGDVAVYTWEENAVNI-SC 427

Query: 420 TAICTPEPI-IAWYFEGEALIQNHRRNV-----TNDGTLVLKDLDKSDSGTYTCVASSRH 473
                P  + I W  +G  L   +  NV      +   L +    ++D G+Y C AS+  
Sbjct: 428 EVQAHPSDVSIVWLRDGLQLPNANATNVKIFRTPSSSYLQINPGSENDFGSYNCTASNEL 487

Query: 474 G 474
           G
Sbjct: 488 G 488



 Score = 81.0 bits (191), Expect = 2e-13
 Identities = 92/352 (26%), Positives = 133/352 (37%), Gaps = 35/352 (9%)

Query: 165 LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR 224
           L +  A   DAG Y+CIA N     ES +  +KI  K      P       G      C 
Sbjct: 71  LTLYKAGTEDAGVYKCIATNGDQQAESTV-KVKIFQKITFRNAPSPQEFTEGDIADIICD 129

Query: 225 VGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAE-NSVGAVS 282
           +   P P VLW+       M    R K L +  L++  +   DEG Y+CE    S G + 
Sbjct: 130 IESSPPPTVLWKYKGRKIQMDKDVRFKELSNNHLQIRGIKKTDEGPYTCEGRLMSRGEID 189

Query: 283 ASGYLTVYDP-PSINLSPNSVN--VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGM 339
                 + +  P+I +    VN   + G   + TC   G PEP + W+  G   ++  G 
Sbjct: 190 FRVIKVIVNVLPTIRVWQTEVNATADVGQPVKLTCAVDGYPEPMVTWTRNG--VVLEAG- 246

Query: 340 SRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD--DDRPP 397
             +KY        +T+L +   D+ +      C A N AG S     L V          
Sbjct: 247 --EKYSFNEDGSEMTLLEVAKLDEGE----YTCIAKNKAGESEQELSLRVFDSVLVFAVK 300

Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN-----DGTL 452
           P IT   +   L  +      C A   P P I+W + G    +  + ++       DG +
Sbjct: 301 PKITYIINTTALETEEQVTLTCEASGDPTPTISWSYGGNVFSEGEQAHLNRIYQSLDGNV 360

Query: 453 V-----------LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIH 493
           V           LK +  +D+G Y C A S  G+   S  L V     P IH
Sbjct: 361 VTRSDARVSSLNLKHVKYTDAGQYLCTARSAIGEDEQSAYLEV--RYAPKIH 410



 Score = 66.1 bits (154), Expect = 6e-09
 Identities = 79/295 (26%), Positives = 113/295 (38%), Gaps = 36/295 (12%)

Query: 27  QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
           QP  L C   G P P + W + GV++ +    S    G    L         D G Y C 
Sbjct: 218 QPVKLTCAVDGYPEPMVTWTRNGVVLEAGEKYSFNEDGSEMTLLEV---AKLDEGEYTCI 274

Query: 87  ATNSYGTARSRNATLHVAVLREEFRLEPE------SKQSAQGDTVVLECLPPRGSPEPNV 140
           A N  G +  +  +L V      F ++P+      +      + V L C    G P P +
Sbjct: 275 AKNKAGES-EQELSLRVFDSVLVFAVKPKITYIINTTALETEEQVTLTC-EASGDPTPTI 332

Query: 141 YWKKNGQTLLFDGDSRMHL------VDGGNLVIQDAR----------QTDAGRYQCIARN 184
            W   G   +F    + HL      +DG  +   DAR           TDAG+Y C AR+
Sbjct: 333 SWSYGGN--VFSEGEQAHLNRIYQSLDGNVVTRSDARVSSLNLKHVKYTDAGQYLCTARS 390

Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRRSA-GGG 242
           A G  E + A L++   P  I G   V     ++V   C V   P    ++W R      
Sbjct: 391 AIGEDEQS-AYLEVRYAP-KIHGDVAVYTWEENAVNISCEVQAHPSDVSIVWLRDGLQLP 448

Query: 243 NMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
           N     VK+    S   L+++     D G Y+C A N +G  S    L   + PS
Sbjct: 449 NANATNVKIFRTPSSSYLQINPGSENDFGSYNCTASNELGTESKEFLLIQAEVPS 503



 Score = 61.7 bits (143), Expect = 1e-07
 Identities = 84/378 (22%), Positives = 144/378 (38%), Gaps = 32/378 (8%)

Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG---NMPLG 247
           S++ +L++ I P   T  E      G S  F C V G     + W   +G     N P  
Sbjct: 7   SSVVSLEVQITP---THGE---ISLGESKFFMCEVAG-VAKHIDWFGPSGDRIEQNSPDI 59

Query: 248 RVKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
            V   D+ S  L L      D G Y C A N      ++  + ++   +   +P+     
Sbjct: 60  TVTRNDESSSILTLYKAGTEDAGVYKCIATNGDQQAESTVKVKIFQKITFRNAPSPQEFT 119

Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
            G++A   C     P PT+ W  +G +      M +D        + + +  I  TD+  
Sbjct: 120 EGDIADIICDIESSPPPTVLWKYKGRKI----QMDKDVRFKELSNNHLQIRGIKKTDEGP 175

Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
              T     ++     F   K+ V      P   +     N T  +       C     P
Sbjct: 176 Y--TCEGRLMSRGEIDFRVIKVIVNV---LPTIRVWQTEVNATADVGQPVKLTCAVDGYP 230

Query: 426 EPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
           EP++ W   G  L    + +   DG+ + L ++ K D G YTC+A ++ G+     +L V
Sbjct: 231 EPMVTWTRNGVVLEAGEKYSFNEDGSEMTLLEVAKLDEGEYTCIAKNKAGESEQELSLRV 290

Query: 485 -DS----PINPNIHFFRAADVSSLPGPPTKPITHNVT-DTSVTLSWSQNNKIGSSSILGY 538
            DS     + P I +    + ++L       +T   + D + T+SWS    + S     +
Sbjct: 291 FDSVLVFAVKPKITYI--INTTALETEEQVTLTCEASGDPTPTISWSYGGNVFSEGEQAH 348

Query: 539 QVEVFSRETLSGNNTPRN 556
              ++  ++L GN   R+
Sbjct: 349 LNRIY--QSLDGNVVTRS 364


>UniRef50_Q8NFA8 Cluster: Transmembrane receptor PTK7-2; n=18;
           Euteleostomi|Rep: Transmembrane receptor PTK7-2 - Homo
           sapiens (Human)
          Length = 1030

 Score =  117 bits (281), Expect = 2e-24
 Identities = 87/321 (27%), Positives = 146/321 (45%), Gaps = 23/321 (7%)

Query: 14  IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT------HRSILPAGGLF 67
           ++  P DV VAR++ A  +C+    P P+++W       +++        R+ + A G  
Sbjct: 227 VVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSL 286

Query: 68  FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
            L     R   +AG+Y C      G      ATLH+A + +    EP    +   + V  
Sbjct: 287 LLTQVRPR---NAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVT- 342

Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
            CLPP+G PEP+V+W+  G  L   G  R++   G  LV+ +  ++DAG Y C A N AG
Sbjct: 343 -CLPPKGLPEPSVWWEHAGVRLPTHG--RVYQ-KGHELVLANIAESDAGVYTCHAANLAG 398

Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
            R   +  + +   P  +  P+D   + G      C     P P V+W R+    +    
Sbjct: 399 QRRQDV-NITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISED-S 456

Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN--LSPNSVNVE 305
           R +V  +G+LR+++V + D   Y C +    G++ A   + V D  S+   ++ N+  + 
Sbjct: 457 RFEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLDGSSLPEWVTDNAGTLH 516

Query: 306 SGNVAR-----FTCTATGRPE 321
              V R     +TC A+  P+
Sbjct: 517 FARVTRDDAGNYTCIASNGPQ 537



 Score =  101 bits (243), Expect = 9e-20
 Identities = 126/479 (26%), Positives = 187/479 (39%), Gaps = 44/479 (9%)

Query: 15  IEQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
           I+QP      + + A L C    +P P  + W   G   V DT R       L F  A  
Sbjct: 35  IKQPSSQDALQGRRALLRCEVE-APGPVHVYWLLDGA-PVQDTERRFAQGSSLSF--AAV 90

Query: 74  GRVHSDAGVYWCEATNSYG--TARSRNATLHVAVLREE--FRLEPESKQSAQGDT-VVLE 128
            R+  D+G + C A +      ARS NA+ ++  +         P S+   Q  T V L 
Sbjct: 91  DRLQ-DSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 149

Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAA 186
           C    G P P   W ++G T L DG S  H V     NL ++ A    +G Y C A +A 
Sbjct: 150 CHID-GHPRPTYQWFRDG-TPLSDGQSN-HTVSSKERNLTLRPAGPEHSGLYSCCAHSAF 206

Query: 187 GTR-ESAIATLKIHIKPY--LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSA 239
           G    S   TL I  + +  ++  P+DVV        F C+    P P + W        
Sbjct: 207 GQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPI 266

Query: 240 GGGNMP--LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSIN 296
              + P  L R  V  +GSL L  V   + G Y C  +   G  +     L + +   + 
Sbjct: 267 TNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMP 326

Query: 297 LSPNSVNVESGNVARFTCTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
           L    V   +G+  R TC    G PEP+++W   G R    P   R       V+     
Sbjct: 327 LFEPRV-FTAGSEERVTCLPPKGLPEPSVWWEHAGVR---LPTHGR-------VYQKGHE 375

Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
           L + +  ++D+     C A N AG       +TV +      P     P +  L      
Sbjct: 376 LVLANIAESDA-GVYTCHAANLAGQRRQDVNITVAT-----VPSWLKKPQDSQLEEGKPG 429

Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
              C    TP+P + WY     + ++ R  V  +GTL +  ++  D   Y C++S+  G
Sbjct: 430 YLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCMSSTPAG 488



 Score = 88.6 bits (210), Expect = 9e-16
 Identities = 88/328 (26%), Positives = 134/328 (40%), Gaps = 23/328 (7%)

Query: 12  PYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFL 69
           P +++ P  +  +      TL C   G P P  +W++ G  L    ++ ++        L
Sbjct: 128 PVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTL 187

Query: 70  RATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFR---LEPESKQSAQGDTV 125
           R   G  HS  G+Y C A +++G A  S+N TL +A   E F    L P+    A+ +  
Sbjct: 188 RPA-GPEHS--GLYSCCAHSAFGQACSSQNFTLSIA--DESFARVVLAPQDVVVARYEEA 242

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL-----VDGGNLVIQDARQTDAGRYQC 180
           +  C      P P++ W    +T + +     HL        G+L++   R  +AG Y+C
Sbjct: 243 MFHC-QFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRC 301

Query: 181 IARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
           I +   G      ATL +  I+   +  P    A +   VT      G P P V W  + 
Sbjct: 302 IGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTC-LPPKGLPEPSVWWEHA- 359

Query: 240 GGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
            G  +P  GRV       L L N+  +D G Y+C A N  G       +TV   PS    
Sbjct: 360 -GVRLPTHGRV-YQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKK 417

Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFW 326
           P    +E G      C     P+PT+ W
Sbjct: 418 PQDSQLEEGKPGYLDCLTQATPKPTVVW 445



 Score = 83.0 bits (196), Expect = 4e-14
 Identities = 97/384 (25%), Positives = 151/384 (39%), Gaps = 36/384 (9%)

Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
           F  +P S+ + QG   +L C      P  +VYW  +G  +    D+      G +L    
Sbjct: 34  FIKQPSSQDALQGRRALLRCEVEAPGPV-HVYWLLDGAPVQ---DTERRFAQGSSLSFAA 89

Query: 170 A-RQTDAGRYQCIARNAAGTRESAIATLKIHIK-----PYLITGP-EDVVAQTGSSVTFQ 222
             R  D+G +QC+AR+     E+  A    +IK     P ++  P  +   Q  + VT +
Sbjct: 90  VDRLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 149

Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVG-A 280
           C + G P P   W R     +       V   + +L L        G YSC A ++ G A
Sbjct: 150 CHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQA 209

Query: 281 VSASGY-LTVYDPP--SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337
            S+  + L++ D     + L+P  V V     A F C  + +P P++ W  E    I   
Sbjct: 210 CSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNR 269

Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV-RGKLTVTSDDDRP 396
                   AT   +G  +LT     +  +     C      G   +    L +   +D P
Sbjct: 270 SRPPHLRRATVFANGSLLLT---QVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMP 326

Query: 397 ---PPIITNGPSNQT--LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT 451
              P + T G   +   LP K +          PEP + W   G  L   H R       
Sbjct: 327 LFEPRVFTAGSEERVTCLPPKGL----------PEPSVWWEHAGVRL-PTHGRVYQKGHE 375

Query: 452 LVLKDLDKSDSGTYTCVASSRHGK 475
           LVL ++ +SD+G YTC A++  G+
Sbjct: 376 LVLANIAESDAGVYTCHAANLAGQ 399



 Score = 74.9 bits (176), Expect = 1e-11
 Identities = 53/143 (37%), Positives = 71/143 (49%), Gaps = 12/143 (8%)

Query: 63  AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122
           AG L F R T      DAG Y C A+N        +  L VAV    F++EPE     QG
Sbjct: 512 AGTLHFARVTR----DDAGNYTCIASNGPQGQIRAHVQLTVAVFIT-FKVEPERTTVYQG 566

Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS---RMHLVDGGNLVIQDARQTDAGRYQ 179
            T +L+C   +G P+P + WK  G+  + D      RMH+   G+LVI D    D+GRY 
Sbjct: 567 HTALLQC-EAQGDPKPLIQWK--GKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYT 623

Query: 180 CIARNAAGTRESAIATLKIHIKP 202
           CIA N+   + +  A L +  KP
Sbjct: 624 CIAGNSCNIKHTE-APLYVVDKP 645



 Score = 60.1 bits (139), Expect = 4e-07
 Identities = 44/148 (29%), Positives = 60/148 (40%), Gaps = 4/148 (2%)

Query: 150 LFDGDSRMHLV--DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG 207
           + DG S    V  + G L      + DAG Y CIA N    +  A   L + +       
Sbjct: 498 VLDGSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFITFKVE 557

Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSAGGGNMPLG-RVKVLDDGSLRLDNVILA 265
           PE      G +   QC   GDP P + W+ +        LG R+ +  +GSL + +V   
Sbjct: 558 PERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPE 617

Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPP 293
           D G Y+C A NS         L V D P
Sbjct: 618 DSGRYTCIAGNSCNIKHTEAPLYVVDKP 645



 Score = 49.6 bits (113), Expect = 5e-04
 Identities = 44/153 (28%), Positives = 61/153 (39%), Gaps = 11/153 (7%)

Query: 255 GSLRLDNVILADEGEYSCEAENSV-GAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313
           G+L    V   D G Y+C A N   G + A   LTV    +  + P    V  G+ A   
Sbjct: 513 GTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQ 572

Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
           C A G P+P + W  +G   I+ P     + H   +F   + L I+D    DS     C 
Sbjct: 573 CEAQGDPKPLIQW--KGKDRILDPTKLGPRMH---IFQNGS-LVIHDVAPEDS-GRYTCI 625

Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN 406
           A N          L V    D+P P  + GP +
Sbjct: 626 AGNSCNIKHTEAPLYVV---DKPVPEESEGPGS 655



 Score = 44.4 bits (100), Expect = 0.019
 Identities = 27/89 (30%), Positives = 45/89 (50%), Gaps = 4/89 (4%)

Query: 404 PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH---RRNVTNDGTLVLKDLDKS 460
           P   T+     A+  C A   P+P+I W  +   L       R ++  +G+LV+ D+   
Sbjct: 558 PERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPE 617

Query: 461 DSGTYTCVA-SSRHGKYVWSGALLVDSPI 488
           DSG YTC+A +S + K+  +   +VD P+
Sbjct: 618 DSGRYTCIAGNSCNIKHTEAPLYVVDKPV 646



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 16/64 (25%), Positives = 30/64 (46%)

Query: 3   DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
           D  +T    P  +++P D  +   +P  L+C    +P P + WY+  +L+  D+   +  
Sbjct: 403 DVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFK 462

Query: 63  AGGL 66
            G L
Sbjct: 463 NGTL 466


>UniRef50_Q4KMQ7 Cluster: NRCAM protein; n=10; Euteleostomi|Rep:
           NRCAM protein - Homo sapiens (Human)
          Length = 771

 Score =  117 bits (281), Expect = 2e-24
 Identities = 134/497 (26%), Positives = 197/497 (39%), Gaps = 57/497 (11%)

Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175
           +K+  +G+ + LEC+   G P P +YW K    L    +  ++      L I    + D+
Sbjct: 273 NKEELRGNVLSLECIA-EGLPTPIIYWAKEDGML--PKNRTVYKNFEKTLQIIHVSEADS 329

Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
           G YQCIA+NA G     I+ +++   PY IT P+++V   G   T  CR  G+P P + W
Sbjct: 330 GNYQCIAKNALGAIHHTIS-VRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISW 388

Query: 236 RRSAGGGNM-PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-DPP 293
             +     + P    + +D  ++   NV       Y C A N  G + A+ ++ V  +PP
Sbjct: 389 LTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPP 448

Query: 294 SINLSPNSV-NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA-VFD 351
            I    N++  V +   A   C   G P PT+ W         F G      H    V  
Sbjct: 449 RILTPANTLYQVIANRPALLDCAFFGSPLPTIEW---------FKGAKGSALHEDIYVLH 499

Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
               L I    K DS  T  C A N  G +     L +     +    I   P    +  
Sbjct: 500 ENGTLEIPVAQK-DSTGTYTCVARNKLGMAKNEVHLEI-----KDATWIVKQPEYAVVQR 553

Query: 412 KSMAVFPCTAIC--TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
            SM  F C      T    + W  +   L  + R  V  D  LV+ D+   DSGTYTCVA
Sbjct: 554 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH-LVVADVSDDDSGTYTCVA 612

Query: 470 SSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWS---Q 526
           ++            +DS     +       V  +P PP      +  D SV LSW+    
Sbjct: 613 NT-----------TLDS-----VSASAVLSVVDVPNPPFDLELTDQLDKSVQLSWTPGDD 656

Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFI 586
           NN   +  I+ Y+ +   +  L  + T  +            QT   +K L P + Y F 
Sbjct: 657 NNSPITKFIIEYE-DAMHKPGLWHHQTEVSGT----------QTTAQLK-LSPYVNYSFR 704

Query: 587 VRTENSHGLSGPSPVSD 603
           V   NS G S PS  S+
Sbjct: 705 VMAVNSIGKSLPSEASE 721



 Score =  109 bits (263), Expect = 3e-22
 Identities = 92/292 (31%), Positives = 132/292 (45%), Gaps = 21/292 (7%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSDTHRSILPAGGLF 67
           APY I  P ++ ++  +  TL CRA G+P P I W   GV   +   D  R I   G   
Sbjct: 354 APYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKI--DGDTI 411

Query: 68  FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR-LEPESK--QSAQGDT 124
                  R    + VY C A+N YG      A   V VL E  R L P +   Q      
Sbjct: 412 IFSNVQER---SSAVYQCNASNEYGYLL---ANAFVNVLAEPPRILTPANTLYQVIANRP 465

Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
            +L+C    GSP P + W K  +      D  + L + G L I  A++   G Y C+ARN
Sbjct: 466 ALLDC-AFFGSPLPTIEWFKGAKGSALHEDIYV-LHENGTLEIPVAQKDSTGTYTCVARN 523

Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD--VLWRRSAGGG 242
             G  ++ +  L+I    +++  PE  V Q GS V+F+C+V  D      VLW +     
Sbjct: 524 KLGMAKNEV-HLEIKDATWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKD--NR 580

Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
            +P      +D   L + +V   D G Y+C A  ++ +VSAS  L+V D P+
Sbjct: 581 ELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPN 632



 Score = 87.0 bits (206), Expect = 3e-15
 Identities = 73/289 (25%), Positives = 121/289 (41%), Gaps = 14/289 (4%)

Query: 30  TLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
           +L C A G P+P I W K  G+L  + T            L+  H    +D+G Y C A 
Sbjct: 283 SLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT----LQIIHVS-EADSGNYQCIAK 337

Query: 89  NSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
           N+ G       T+ V V    + +  P++   + G+   L C    G+P+P + W  NG 
Sbjct: 338 NALGAIHH---TISVRVKAAPYWITAPQNLVLSPGEDGTLICRA-NGNPKPRISWLTNGV 393

Query: 148 TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG 207
            +    D     +DG  ++  + ++  +  YQC A N  G    A A + +  +P  I  
Sbjct: 394 PIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYL-LANAFVNVLAEPPRILT 452

Query: 208 PEDVVAQTGSS--VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA 265
           P + + Q  ++      C   G PLP + W + A G  +      + ++G+L +      
Sbjct: 453 PANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKD 512

Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
             G Y+C A N +G      +L + D   I   P    V+ G++  F C
Sbjct: 513 STGTYTCVARNKLGMAKNEVHLEIKDATWIVKQPEYAVVQRGSMVSFEC 561



 Score = 68.1 bits (159), Expect = 1e-09
 Identities = 52/181 (28%), Positives = 79/181 (43%), Gaps = 10/181 (5%)

Query: 10  EAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGL 66
           + P I +Q P D  +   +   + C A G P P+  W + G    +  D   ++ P  G 
Sbjct: 38  QPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGT 97

Query: 67  FFLRA-THGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGD 123
             +   + G+  +  GVY C A N  G A S N  +  +   L  + +LEP + QS  G 
Sbjct: 98  LIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQS--GQ 155

Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIA 182
           ++VL C PP G P P ++W  N    L   + R+     G+L   +    D    Y C A
Sbjct: 156 SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSE-RVSQGLNGDLYFSNVLPEDTREDYICYA 214

Query: 183 R 183
           R
Sbjct: 215 R 215



 Score = 58.4 bits (135), Expect = 1e-06
 Identities = 67/305 (21%), Positives = 116/305 (38%), Gaps = 30/305 (9%)

Query: 200 IKPYLIT--GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257
           ++P  IT   P+D +     ++  QC   G P P   W R+    ++    +  +  G+ 
Sbjct: 37  VQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTG 96

Query: 258 RLDNVILAD------EGEYSCEAENSVGAVSASGYLT--VYDPPSINLSPNSVNVESGNV 309
            L   I+++      EG Y C A N  GA  ++  +      P         + ++SG  
Sbjct: 97  TLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQS 156

Query: 310 ARFTC-TATGRPEPTMFWSVEGNRTI-----IFPGMSRDKYHATAV-----FDGVTVLTI 358
               C    G P P +FW     + +     +  G++ D Y +  +      D +     
Sbjct: 157 LVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARF 216

Query: 359 NDTDKNDSRNTIVCSAVNYAG-SSFVRGKLTVT------SDDDRPPPIIT--NGPSNQTL 409
           N T     +  I    ++    +  +   L+ T      S  +RPP  +T     SN+  
Sbjct: 217 NHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEE 276

Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
              ++    C A   P PII W  E   L +N       + TL +  + ++DSG Y C+A
Sbjct: 277 LRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIA 336

Query: 470 SSRHG 474
            +  G
Sbjct: 337 KNALG 341



 Score = 54.4 bits (125), Expect = 2e-05
 Identities = 56/218 (25%), Positives = 90/218 (41%), Gaps = 12/218 (5%)

Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVI----QDARQTDAGR 177
           + +V++C   +G P P+  W +NG     D D  + +  G G L+I    +   +T  G 
Sbjct: 56  ENIVIQC-EAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGV 114

Query: 178 YQCIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLW 235
           YQC ARN  G   S    ++    P +     E +  Q+G S+   CR   G P P + W
Sbjct: 115 YQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFW 174

Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGE-YSCEAE-NSVGAVSASGYLTVYDPP 293
             ++        RV    +G L   NV+  D  E Y C A  N    +     ++V    
Sbjct: 175 MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISV-KVI 233

Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGN 331
           S++   +++     +   F    + R  P  F + EGN
Sbjct: 234 SVDELNDTIAANLSD-TEFYGAKSSRERPPTFLTPEGN 270



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 47/192 (24%), Positives = 71/192 (36%), Gaps = 12/192 (6%)

Query: 287 LTVYDPPSINL-SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345
           L +  PP+I   SP    ++        C A G+P P+  W+  G    I     +D   
Sbjct: 34  LDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDI----DKDPLV 89

Query: 346 ATAVFDGVTVLTINDTDKNDSRNTIV-CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404
                 G  ++ I    K ++   +  C+A N  G++ V   + V     R P       
Sbjct: 90  TMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAA-VSNNIVVR--PSRSPLWTKEKL 146

Query: 405 SNQTLPIKSMAVFPC-TAICTPEPIIAWYFEG-EALIQNHRRNVTNDGTLVLKDLDKSDS 462
              TL      V PC   I  P PII W     + L Q+ R +   +G L   ++   D+
Sbjct: 147 EPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDT 206

Query: 463 -GTYTCVASSRH 473
              Y C A   H
Sbjct: 207 REDYICYARFNH 218


>UniRef50_Q4S5S6 Cluster: Chromosome 9 SCAF14729, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 9 SCAF14729, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 1238

 Score =  116 bits (279), Expect = 4e-24
 Identities = 83/286 (29%), Positives = 130/286 (45%), Gaps = 12/286 (4%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
           AP+ +E+P D+ +A  +   L CR+ G+P P + W+  G  +   T +  +   G   + 
Sbjct: 338 APFWLEKPADLVLAPEEDGRLVCRSDGAPRPTVTWFINGEPIDPSTLQPNVEVSGETVVL 397

Query: 71  ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL---EPESKQSAQGDTVVL 127
            T   +++   VY C A+N YG      A   V VL    R+     E  +  +G    L
Sbjct: 398 RTVTTLNN--AVYQCNASNPYGYLL---ANAFVNVLHATPRILGSRNEYLKVIEGSRAFL 452

Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
           +C    GSP P + W K GQ  L     R H    G L I++ +  D G Y C+  N AG
Sbjct: 453 DCRY-FGSPVPELRWSKYGQGSLEGNRFRTH--SNGTLEIKNIQVVDQGAYLCVVSNVAG 509

Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
             E+ +  +++     ++T P D+    G+ V F+C V  D    V      G   + LG
Sbjct: 510 RDENQVR-IEVKEPTLIVTRPTDMKVIRGADVRFECAVKTDATTPVTTTWMKGTKPVTLG 568

Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
               +D+ +L + N+  AD G Y+C  ++ +   SAS  L V D P
Sbjct: 569 WRISMDESNLVISNINTADGGNYTCLVKSELEQKSASARLMVMDRP 614



 Score = 91.9 bits (218), Expect = 1e-16
 Identities = 85/308 (27%), Positives = 124/308 (40%), Gaps = 13/308 (4%)

Query: 31  LNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
           L C A G P+P I W K G  LVV    RS + A     +         DAG Y C ATN
Sbjct: 267 LECIAAGVPTPHITWRKDGEDLVV----RSPVKAKNFNKMIQIPRASFEDAGEYVCTATN 322

Query: 90  SYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
                +    T+ V V    F LE P     A  +   L C    G+P P V W  NG+ 
Sbjct: 323 KLDYIQH---TITVQVKAAPFWLEKPADLVLAPEEDGRLVCRSD-GAPRPTVTWFINGEP 378

Query: 149 LLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI-TG 207
           +          V G  +V++     +   YQC A N  G   +      +H  P ++ + 
Sbjct: 379 IDPSTLQPNVEVSGETVVLRTVTTLNNAVYQCNASNPYGYLLANAFVNVLHATPRILGSR 438

Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267
            E +    GS     CR  G P+P++ W +  G G++   R +   +G+L + N+ + D+
Sbjct: 439 NEYLKVIEGSRAFLDCRYFGSPVPELRWSK-YGQGSLEGNRFRTHSNGTLEIKNIQVVDQ 497

Query: 268 GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA-TGRPEPTMFW 326
           G Y C   N  G       + V +P  I   P  + V  G   RF C   T    P    
Sbjct: 498 GAYLCVVSNVAGRDENQVRIEVKEPTLIVTRPTDMKVIRGADVRFECAVKTDATTPVTTT 557

Query: 327 SVEGNRTI 334
            ++G + +
Sbjct: 558 WMKGTKPV 565



 Score = 89.4 bits (212), Expect = 5e-16
 Identities = 90/376 (23%), Positives = 158/376 (42%), Gaps = 27/376 (7%)

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT--DAGRYQ 179
           G+ ++LEC+   G P P++ W+K+G+ L+     +       N +IQ  R +  DAG Y 
Sbjct: 262 GEELLLECIAA-GVPTPHITWRKDGEDLVVRSPVK---AKNFNKMIQIPRASFEDAGEYV 317

Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
           C A N     +  I T+++   P+ +  P D+V          CR  G P P V W  + 
Sbjct: 318 CTATNKLDYIQHTI-TVQVKAAPFWLEKPADLVLAPEEDGRLVCRSDGAPRPTVTWFING 376

Query: 240 GGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV-YDPPSINL 297
              +    +  V   G ++ L  V   +   Y C A N  G + A+ ++ V +  P I  
Sbjct: 377 EPIDPSTLQPNVEVSGETVVLRTVTTLNNAVYQCNASNPYGYLLANAFVNVLHATPRILG 436

Query: 298 SPNS-VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
           S N  + V  G+ A   C   G P P + WS  G  ++   G +R + H+    +   + 
Sbjct: 437 SRNEYLKVIEGSRAFLDCRYFGSPVPELRWSKYGQGSL--EG-NRFRTHSNGTLEIKNIQ 493

Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416
            ++       +   +C   N AG    + ++ V     + P +I   P++  +   +   
Sbjct: 494 VVD-------QGAYLCVVSNVAGRDENQVRIEV-----KEPTLIVTRPTDMKVIRGADVR 541

Query: 417 FPCTAIC-TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
           F C        P+   + +G   +    R   ++  LV+ +++ +D G YTC+  S   +
Sbjct: 542 FECAVKTDATTPVTTTWMKGTKPVTLGWRISMDESNLVISNINTADGGNYTCLVKSELEQ 601

Query: 476 YVWSGALLV-DSPINP 490
              S  L+V D P  P
Sbjct: 602 KSASARLMVMDRPDPP 617



 Score = 74.9 bits (176), Expect = 1e-11
 Identities = 76/319 (23%), Positives = 125/319 (39%), Gaps = 22/319 (6%)

Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEA 274
           G  +  +C   G P P + WR+  G   +    VK  + +  +++      D GEY C A
Sbjct: 262 GEELLLECIAAGVPTPHITWRKD-GEDLVVRSPVKAKNFNKMIQIPRASFEDAGEYVCTA 320

Query: 275 ENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334
            N +  +  +  + V   P     P  + +      R  C + G P PT+ W + G    
Sbjct: 321 TNKLDYIQHTITVQVKAAPFWLEKPADLVLAPEEDGRLVCRSDGAPRPTVTWFINGEP-- 378

Query: 335 IFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394
           I P   +     +    G TV+    T  N++     C+A N  G       + V     
Sbjct: 379 IDPSTLQPNVEVS----GETVVLRTVTTLNNA--VYQCNASNPYGYLLANAFVNVLH--- 429

Query: 395 RPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTL 452
             P I+  G  N+ L +   S A   C    +P P + W   G+  ++ +R    ++GTL
Sbjct: 430 ATPRIL--GSRNEYLKVIEGSRAFLDCRYFGSPVPELRWSKYGQGSLEGNRFRTHSNGTL 487

Query: 453 VLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPIT 512
            +K++   D G Y CV S+  G+      + V     P +   R  D+  + G   +   
Sbjct: 488 EIKNIQVVDQGAYLCVVSNVAGRDENQVRIEVK---EPTLIVTRPTDMKVIRGADVRFEC 544

Query: 513 HNVTD--TSVTLSWSQNNK 529
              TD  T VT +W +  K
Sbjct: 545 AVKTDATTPVTTTWMKGTK 563



 Score = 55.6 bits (128), Expect = 8e-06
 Identities = 41/144 (28%), Positives = 62/144 (43%), Gaps = 4/144 (2%)

Query: 10  EAPYIIEQPLDVTVARHQPA-TLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGL 66
           + P II+Q +   +   + A  + C A G+P P   W + G    V  D   S+    G 
Sbjct: 1   QPPTIIKQSMKEHIVDAKDAMVIECEAKGNPHPIFSWRRNGRYYNVARDPQASMRRHSGT 60

Query: 67  FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
             + A +     +A  Y C A+N YG+A S    L +       R   E    + G  +V
Sbjct: 61  LDIYARNNPEQYEAE-YQCVASNMYGSAYSNKIRLRLYRAPVWPREIIEPVVISAGLPLV 119

Query: 127 LECLPPRGSPEPNVYWKKNGQTLL 150
           L C PP G P+P  YW  + + +L
Sbjct: 120 LSCDPPPGPPKPETYWMSSCECVL 143



 Score = 42.3 bits (95), Expect = 0.078
 Identities = 32/121 (26%), Positives = 54/121 (44%), Gaps = 6/121 (4%)

Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQ--TLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQ 179
           D +V+EC   +G+P P   W++NG+   +  D  + M    G  ++  ++  +     YQ
Sbjct: 19  DAMVIEC-EAKGNPHPIFSWRRNGRYYNVARDPQASMRRHSGTLDIYARNNPEQYEAEYQ 77

Query: 180 CIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQC-RVGGDPLPDVLWRR 237
           C+A N  G+  S    L+++  P +     E VV   G  +   C    G P P+  W  
Sbjct: 78  CVASNMYGSAYSNKIRLRLYRAPVWPREIIEPVVISAGLPLVLSCDPPPGPPKPETYWMS 137

Query: 238 S 238
           S
Sbjct: 138 S 138



 Score = 41.9 bits (94), Expect = 0.10
 Identities = 56/257 (21%), Positives = 96/257 (37%), Gaps = 20/257 (7%)

Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
           S +S  V  G      C A G P P + W  +G   ++   +    ++         ++ 
Sbjct: 253 SSSSTLVLLGEELLLECIAAGVPTPHITWRKDGEDLVVRSPVKAKNFN--------KMIQ 304

Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
           I      D+    VC+A N     +++  +TV     +  P     P++  L  +     
Sbjct: 305 IPRASFEDA-GEYVCTATNKL--DYIQHTITV---QVKAAPFWLEKPADLVLAPEEDGRL 358

Query: 418 PCTAICTPEPIIAWYFEGEALIQNH-RRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGK 475
            C +   P P + W+  GE +  +  + NV   G T+VL+ +   ++  Y C AS+ +G 
Sbjct: 359 VCRSDGAPRPTVTWFINGEPIDPSTLQPNVEVSGETVVLRTVTTLNNAVYQCNASNPYG- 417

Query: 476 YVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSI 535
           Y+ + A +      P I   R   +  + G                L WS   K G  S+
Sbjct: 418 YLLANAFVNVLHATPRILGSRNEYLKVIEGSRAFLDCRYFGSPVPELRWS---KYGQGSL 474

Query: 536 LGYQVEVFSRETLSGNN 552
            G +    S  TL   N
Sbjct: 475 EGNRFRTHSNGTLEIKN 491


>UniRef50_A7SVH4 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 412

 Score =  116 bits (279), Expect = 4e-24
 Identities = 108/418 (25%), Positives = 176/418 (42%), Gaps = 49/418 (11%)

Query: 78  SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSP 136
           +DAG Y C A N+ G    ++    V      F+ +   +  + +G  + L C    G P
Sbjct: 12  TDAGRYVCTAVNAIGIIH-KSTNYIVWYENRPFKTKIGNNLTTMKGRKLTLIC-HATGRP 69

Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
            P + W + G+ +      R  + + G+L+++    +D GRY C ARNA G   +   T+
Sbjct: 70  RPTITWFRGGEEM------RTKVTNNGSLILEKVSSSDIGRYTCTARNAFGKDNANSTTI 123

Query: 197 KIHI-KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL-DD 254
                 P  ++  +++   T + +   C V G P P V+W +    G + +G   V+ D+
Sbjct: 124 PPGDGSPVKVSVGDNITVITDTPLLIDCEVSGIPFPSVVWVKD---GRVLMGEGYVIFDN 180

Query: 255 GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP------------PSINLSPNSV 302
           G+L L     AD G Y+C A NS G    S   T+  P            P+I    ++ 
Sbjct: 181 GTLVLRRARPADSGRYTCTANNSRGKDHISSQPTIERPVAPRDIPLGDGSPTIARIADNA 240

Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
            V +G+     C ATG P+P++ W  +G R +I  G      + + +   V         
Sbjct: 241 TVLTGSRLTIDCVATGVPKPSIIWRKDG-RELIGAGSYMAPGNGSLLIQQVAA------- 292

Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD-----DRPPPIITNGPSNQTLPIKSMAVF 417
                    C+A N  G   V   + V + D     D  P  +  G    +L    + + 
Sbjct: 293 --SHHGVFTCTATNPVGEDSVSSNIRVRTTDKVEKSDMKPVDVRIGGQVTSLSGVDITL- 349

Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
            C+A   P P I W   G+ +     R       LVL+++  SDSG YTC+AS+  G+
Sbjct: 350 NCSARGLPPPDIEWMNGGKMITVQGPR-------LVLRNVMSSDSGNYTCIASNVVGR 400



 Score =  116 bits (279), Expect = 4e-24
 Identities = 97/361 (26%), Positives = 154/361 (42%), Gaps = 40/361 (11%)

Query: 20  DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
           ++T  + +  TL C A G P P I W++GG     +    +   G L   + +     SD
Sbjct: 50  NLTTMKGRKLTLICHATGRPRPTITWFRGG----EEMRTKVTNNGSLILEKVSS----SD 101

Query: 80  AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
            G Y C A N++G   + + T+         ++      +   DT +L      G P P+
Sbjct: 102 IGRYTCTARNAFGKDNANSTTIPPGD-GSPVKVSVGDNITVITDTPLLIDCEVSGIPFPS 160

Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG--------TRES 191
           V W K+G+ L+ +G     + D G LV++ AR  D+GRY C A N+ G        T E 
Sbjct: 161 VVWVKDGRVLMGEG---YVIFDNGTLVLRRARPADSGRYTCTANNSRGKDHISSQPTIER 217

Query: 192 AIATLKIHI---KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
            +A   I +    P +    ++    TGS +T  C   G P P ++WR+  G   +  G 
Sbjct: 218 PVAPRDIPLGDGSPTIARIADNATVLTGSRLTIDCVATGVPKPSIIWRKD-GRELIGAGS 276

Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI---NLSPNSVNVE 305
                +GSL +  V  +  G ++C A N VG  S S  + V     +   ++ P  V + 
Sbjct: 277 YMAPGNGSLLIQQVAASHHGVFTCTATNPVGEDSVSSNIRVRTTDKVEKSDMKPVDVRIG 336

Query: 306 ------SGNVARFTCTATGRPEPTMFW-------SVEGNRTIIFPGMSRDKYHATAVFDG 352
                 SG      C+A G P P + W       +V+G R ++   MS D  + T +   
Sbjct: 337 GQVTSLSGVDITLNCSARGLPPPDIEWMNGGKMITVQGPRLVLRNVMSSDSGNYTCIASN 396

Query: 353 V 353
           V
Sbjct: 397 V 397



 Score =  104 bits (249), Expect = 2e-20
 Identities = 90/323 (27%), Positives = 140/323 (43%), Gaps = 26/323 (8%)

Query: 163 GNLVIQDARQTDAGRYQCIARNAAGT-RESAIATLKIHIKPYLITGPEDVVAQTGSSVTF 221
           G L I   R TDAGRY C A NA G   +S    +    +P+      ++    G  +T 
Sbjct: 2   GTLSIVLRRTTDAGRYVCTAVNAIGIIHKSTNYIVWYENRPFKTKIGNNLTTMKGRKLTL 61

Query: 222 QCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281
            C   G P P + W R  GG  M   R KV ++GSL L+ V  +D G Y+C A N+ G  
Sbjct: 62  ICHATGRPRPTITWFR--GGEEM---RTKVTNNGSLILEKVSSSDIGRYTCTARNAFGKD 116

Query: 282 SA-SGYLTVYDPPSINLSP-NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGM 339
           +A S  +   D   + +S  +++ V +       C  +G P P++ W  +G R ++  G 
Sbjct: 117 NANSTTIPPGDGSPVKVSVGDNITVITDTPLLIDCEVSGIPFPSVVWVKDG-RVLMGEGY 175

Query: 340 SRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV---TSDDDRP 396
                    +FD  T++       +  R T  C+A N  G   +  + T+    +  D P
Sbjct: 176 --------VIFDNGTLVLRRARPADSGRYT--CTANNSRGKDHISSQPTIERPVAPRDIP 225

Query: 397 ----PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTL 452
                P I     N T+   S     C A   P+P I W  +G  LI         +G+L
Sbjct: 226 LGDGSPTIARIADNATVLTGSRLTIDCVATGVPKPSIIWRKDGRELIGAGSYMAPGNGSL 285

Query: 453 VLKDLDKSDSGTYTCVASSRHGK 475
           +++ +  S  G +TC A++  G+
Sbjct: 286 LIQQVAASHHGVFTCTATNPVGE 308



 Score = 93.1 bits (221), Expect = 4e-17
 Identities = 78/290 (26%), Positives = 129/290 (44%), Gaps = 38/290 (13%)

Query: 20  DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
           ++TV    P  ++C   G P P++ W K G +++ + +  I   G L   RA      +D
Sbjct: 138 NITVITDTPLLIDCEVSGIPFPSVVWVKDGRVLMGEGY-VIFDNGTLVLRRARP----AD 192

Query: 80  AGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESKQSAQ---------GDTVVLEC 129
           +G Y C A NS G    S   T+   V   +  L   S   A+         G  + ++C
Sbjct: 193 SGRYTCTANNSRGKDHISSQPTIERPVAPRDIPLGDGSPTIARIADNATVLTGSRLTIDC 252

Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGT 188
           +   G P+P++ W+K+G+ L+  G    ++  G G+L+IQ    +  G + C A N  G 
Sbjct: 253 VAT-GVPKPSIIWRKDGRELIGAGS---YMAPGNGSLLIQQVAASHHGVFTCTATNPVG- 307

Query: 189 RESAIATLKIH---------IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
            +S  + +++          +KP  +     V + +G  +T  C   G P PD+ W    
Sbjct: 308 EDSVSSNIRVRTTDKVEKSDMKPVDVRIGGQVTSLSGVDITLNCSARGLPPPDIEWMNG- 366

Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
                  G++  +    L L NV+ +D G Y+C A N VG  SAS  + V
Sbjct: 367 -------GKMITVQGPRLVLRNVMSSDSGNYTCIASNVVGRASASTMVNV 409



 Score = 69.7 bits (163), Expect = 4e-10
 Identities = 60/227 (26%), Positives = 93/227 (40%), Gaps = 20/227 (8%)

Query: 266 DEGEYSCEAENSVGAVSAS-GYLTVYDP-PSINLSPNSVNVESGNVARFTCTATGRPEPT 323
           D G Y C A N++G +  S  Y+  Y+  P      N++    G      C ATGRP PT
Sbjct: 13  DAGRYVCTAVNAIGIIHKSTNYIVWYENRPFKTKIGNNLTTMKGRKLTLICHATGRPRPT 72

Query: 324 MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383
           + W   G                T V +  +++    +  +  R T  C+A N  G    
Sbjct: 73  ITWFRGGEEM------------RTKVTNNGSLILEKVSSSDIGRYT--CTARNAFGKD-- 116

Query: 384 RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR 443
               T     D  P  ++ G  N T+   +  +  C     P P + W  +G  L+    
Sbjct: 117 NANSTTIPPGDGSPVKVSVG-DNITVITDTPLLIDCEVSGIPFPSVVWVKDGRVLM-GEG 174

Query: 444 RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
             + ++GTLVL+    +DSG YTC A++  GK   S    ++ P+ P
Sbjct: 175 YVIFDNGTLVLRRARPADSGRYTCTANNSRGKDHISSQPTIERPVAP 221



 Score = 62.9 bits (146), Expect = 5e-08
 Identities = 54/195 (27%), Positives = 82/195 (42%), Gaps = 22/195 (11%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
           +P I     + TV      T++C A G P P+I W K G  ++      + P  G   ++
Sbjct: 230 SPTIARIADNATVLTGSRLTIDCVATGVPKPSIIWRKDGRELIG-AGSYMAPGNGSLLIQ 288

Query: 71  ATHGRVHSDAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQ------SAQGD 123
                 H   GV+ C ATN  G  + S N  +      E+  ++P   +      S  G 
Sbjct: 289 QVAASHH---GVFTCTATNPVGEDSVSSNIRVRTTDKVEKSDMKPVDVRIGGQVTSLSGV 345

Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
            + L C   RG P P++ W   G         +M  V G  LV+++   +D+G Y CIA 
Sbjct: 346 DITLNC-SARGLPPPDIEWMNGG---------KMITVQGPRLVLRNVMSSDSGNYTCIAS 395

Query: 184 NAAGTRESAIATLKI 198
           N  G R SA   + +
Sbjct: 396 NVVG-RASASTMVNV 409


>UniRef50_UPI0000D57760 Cluster: PREDICTED: similar to leucine-rich
           repeats and immunoglobulin-like domains 2; n=1;
           Tribolium castaneum|Rep: PREDICTED: similar to
           leucine-rich repeats and immunoglobulin-like domains 2 -
           Tribolium castaneum
          Length = 756

 Score =  116 bits (278), Expect = 5e-24
 Identities = 68/230 (29%), Positives = 109/230 (47%), Gaps = 13/230 (5%)

Query: 113 EPESKQSA-QGDTVVLECLPPRGSPEPNVY-WKKNGQTLLFDGDSRMHLVDG------GN 164
           EPE +  A +G+ + L C     S  P  + WKK+   ++    +     DG        
Sbjct: 321 EPEPEIMALKGENITLSCTAMSSSNSPMTFQWKKDNVDIINMNINENSSSDGKTTEAVSK 380

Query: 165 LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR 224
           L I   + ++AG+YQC+  N  GT  S  +++ + I P  +  P++V  + G      C 
Sbjct: 381 LNIYRVQHSNAGKYQCVVSNIFGTTYSQKSSISVLIFPTFLKRPDNVTVKAGDVAKLVCA 440

Query: 225 VGGDPLPDVLWRRSAGGGNMPLGRVKVLD----DGSLRLDNVILADEGEYSCEAENSVGA 280
             G+P P++ W++  GG + P  R + +     D S  + NV   D G YSC A N+ G 
Sbjct: 441 AHGEPQPEIAWQKD-GGNDFPAARERRMHVLPADDSFFISNVKPTDMGIYSCTAHNAAGT 499

Query: 281 VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
           +  +  LTVY+ PS   S  +  V +G +    C A+G P+PT+ W   G
Sbjct: 500 IVTNASLTVYEKPSFVKSMENKEVTAGELVVLQCMASGTPKPTITWYKNG 549



 Score =  105 bits (252), Expect = 7e-21
 Identities = 74/287 (25%), Positives = 127/287 (44%), Gaps = 12/287 (4%)

Query: 12  PYIIEQPL-DVTVARHQPATLNCRA-GGSPSP-AIRWYKGGVLVVSDTHRSILPAGGLFF 68
           P + E+P  ++   + +  TL+C A   S SP   +W K  V +++        + G   
Sbjct: 316 PRLTEEPEPEIMALKGENITLSCTAMSSSNSPMTFQWKKDNVDIINMNINENSSSDGKTT 375

Query: 69  LRATHGRV----HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
              +   +    HS+AG Y C  +N +GT  S+ +++ V +    F   P++     GD 
Sbjct: 376 EAVSKLNIYRVQHSNAGKYQCVVSNIFGTTYSQKSSISVLIF-PTFLKRPDNVTVKAGDV 434

Query: 125 VVLECLPPRGSPEPNVYWKKN-GQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIA 182
             L C    G P+P + W+K+ G       + RMH++    +  I + + TD G Y C A
Sbjct: 435 AKLVC-AAHGEPQPEIAWQKDGGNDFPAARERRMHVLPADDSFFISNVKPTDMGIYSCTA 493

Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
            NAAGT  +  A+L ++ KP  +   E+     G  V  QC   G P P + W ++    
Sbjct: 494 HNAAGTIVTN-ASLTVYEKPSFVKSMENKEVTAGELVVLQCMASGTPKPTITWYKNGEPI 552

Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
                     ++  + + + + +D G+Y C   NS+G  +    L V
Sbjct: 553 RATERHFFTAEEQLMIIVDTVQSDSGKYECHLNNSLGEKTGYSLLRV 599



 Score = 92.7 bits (220), Expect = 6e-17
 Identities = 73/287 (25%), Positives = 116/287 (40%), Gaps = 23/287 (8%)

Query: 201 KPYLITGPE-DVVAQTGSSVTFQCRV---GGDPLPDVLWRRSAGGGNMPLGRVKVLDD-- 254
           KP L   PE +++A  G ++T  C        P+     + +    NM +      D   
Sbjct: 315 KPRLTEEPEPEIMALKGENITLSCTAMSSSNSPMTFQWKKDNVDIINMNINENSSSDGKT 374

Query: 255 ----GSLRLDNVILADEGEYSCEAENSVGAV-SASGYLTVYDPPSINLSPNSVNVESGNV 309
                 L +  V  ++ G+Y C   N  G   S    ++V   P+    P++V V++G+V
Sbjct: 375 TEAVSKLNIYRVQHSNAGKYQCVVSNIFGTTYSQKSSISVLIFPTFLKRPDNVTVKAGDV 434

Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
           A+  C A G P+P + W  +G     FP     + H     D   +  +  TD       
Sbjct: 435 AKLVCAAHGEPQPEIAWQKDGGND--FPAARERRMHVLPADDSFFISNVKPTDMG----I 488

Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
             C+A N AG+      LTV        P       N+ +    + V  C A  TP+P I
Sbjct: 489 YSCTAHNAAGTIVTNASLTVYEK-----PSFVKSMENKEVTAGELVVLQCMASGTPKPTI 543

Query: 430 AWYFEGEALIQNHRRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGK 475
            WY  GE +    R   T  +  +++ D  +SDSG Y C  ++  G+
Sbjct: 544 TWYKNGEPIRATERHFFTAEEQLMIIVDTVQSDSGKYECHLNNSLGE 590



 Score = 43.6 bits (98), Expect = 0.034
 Identities = 26/87 (29%), Positives = 36/87 (41%), Gaps = 3/87 (3%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
           +T  E P  ++   +  V   +   L C A G+P P I WYK G  + +           
Sbjct: 506 LTVYEKPSFVKSMENKEVTAGELVVLQCMASGTPKPTITWYKNGEPIRATERHFFTAEEQ 565

Query: 66  LFFLRATHGRVHSDAGVYWCEATNSYG 92
           L  +  T   V SD+G Y C   NS G
Sbjct: 566 LMIIVDT---VQSDSGKYECHLNNSLG 589



 Score = 39.5 bits (88), Expect = 0.55
 Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 4/91 (4%)

Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG----EALIQNHRRNVTNDGTLV 453
           P     P N T+    +A   C A   P+P IAW  +G     A  +     +  D +  
Sbjct: 418 PTFLKRPDNVTVKAGDVAKLVCAAHGEPQPEIAWQKDGGNDFPAARERRMHVLPADDSFF 477

Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
           + ++  +D G Y+C A +  G  V + +L V
Sbjct: 478 ISNVKPTDMGIYSCTAHNAAGTIVTNASLTV 508


>UniRef50_O44329 Cluster: Receptor tyrosine phosphatase; n=1; Hirudo
           medicinalis|Rep: Receptor tyrosine phosphatase - Hirudo
           medicinalis (Medicinal leech)
          Length = 1437

 Score =  116 bits (278), Expect = 5e-24
 Identities = 91/304 (29%), Positives = 142/304 (46%), Gaps = 29/304 (9%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD---THRSILP 62
           V   +AP I   P D  V   + A+  C+A G+P+P + W +G    + D   T  S +P
Sbjct: 29  VDHDDAPRITTAPRDQKVMEGKIASFFCKASGNPAPEVYWKRGWKESLHDKNETKTSNMP 88

Query: 63  AGGLFFLRATHGRVHSDAGVYWCEATNSYG-TARSRNATLHVAVLREEFR-----LE-PE 115
            G +  LR    +   D  +  C A +  G  A +  A LH+    EE +     LE PE
Sbjct: 89  HGSV--LRVDPTKWQKDETIIECVAESGIGHQAATATARLHIYRENEEPKGFPRLLETPE 146

Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175
            +   +    +L+C    G PEP+VYW K+   +    D R+ ++ GG+L I++ + +D 
Sbjct: 147 MRSVEKDRNFILKC-SATGDPEPSVYWLKDNIPVDM-SDKRIQVLPGGSLSIRNGQGSDE 204

Query: 176 GRYQCIARNAAGTRESAIATLKIHIK---PYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
           G+Y+C+A N  GT  S  A+L I I+   P+     ++     G S+   C VGG P+P 
Sbjct: 205 GKYECVAENIHGTVHSFPASLYIRIRRVPPHFSVQIQNKEVPLGGSLNVTCVVGGAPMPH 264

Query: 233 VLWRRS----AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
           V W+          N+P+G+        LRL++V     G Y C   + +G V     +T
Sbjct: 265 VRWKHGDIDLTPENNIPIGK------NVLRLEDV--KQSGTYKCIGSSELGNVEQEINVT 316

Query: 289 VYDP 292
           V  P
Sbjct: 317 VVVP 320



 Score = 87.8 bits (208), Expect = 2e-15
 Identities = 66/229 (28%), Positives = 103/229 (44%), Gaps = 18/229 (7%)

Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFD-GDSRMHLVDGGNLVIQDAR- 171
           P  ++  +G      C    G+P P VYWK+  +  L D  +++   +  G+++  D   
Sbjct: 41  PRDQKVMEGKIASFFC-KASGNPAPEVYWKRGWKESLHDKNETKTSNMPHGSVLRVDPTK 99

Query: 172 -QTDAGRYQCIARNAAGTRESAIATLKIHIK---------PYLITGPEDVVAQTGSSVTF 221
            Q D    +C+A +  G  ++A AT ++HI          P L+  PE    +   +   
Sbjct: 100 WQKDETIIECVAESGIG-HQAATATARLHIYRENEEPKGFPRLLETPEMRSVEKDRNFIL 158

Query: 222 QCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281
           +C   GDP P V W +     +M   R++VL  GSL + N   +DEG+Y C AEN  G V
Sbjct: 159 KCSATGDPEPSVYWLKDNIPVDMSDKRIQVLPGGSLSIRNGQGSDEGKYECVAENIHGTV 218

Query: 282 ---SASGYLTVYD-PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326
               AS Y+ +   PP  ++   +  V  G     TC   G P P + W
Sbjct: 219 HSFPASLYIRIRRVPPHFSVQIQNKEVPLGGSLNVTCVVGGAPMPHVRW 267



 Score = 69.3 bits (162), Expect = 6e-10
 Identities = 75/286 (26%), Positives = 114/286 (39%), Gaps = 26/286 (9%)

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDGS-LR 258
           P + T P D     G   +F C+  G+P P+V W+R            K   +  GS LR
Sbjct: 35  PRITTAPRDQKVMEGKIASFFCKASGNPAPEVYWKRGWKESLHDKNETKTSNMPHGSVLR 94

Query: 259 LD-NVILADEGEYSCEAENSVG--AVSASGYLTVY----DP---PSINLSPNSVNVESGN 308
           +D      DE    C AE+ +G  A +A+  L +Y    +P   P +  +P   +VE   
Sbjct: 95  VDPTKWQKDETIIECVAESGIGHQAATATARLHIYRENEEPKGFPRLLETPEMRSVEKDR 154

Query: 309 VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
                C+ATG PEP+++W  +       P    DK     V  G ++   N    ++ + 
Sbjct: 155 NFILKCSATGDPEPSVYWLKDN-----IPVDMSDK--RIQVLPGGSLSIRNGQGSDEGKY 207

Query: 369 TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428
             V   ++    SF     ++     R PP  +    N+ +P+       C     P P 
Sbjct: 208 ECVAENIHGTVHSF---PASLYIRIRRVPPHFSVQIQNKEVPLGGSLNVTCVVGGAPMPH 264

Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
           + W   G+  I     N    G  VL+  D   SGTY C+ SS  G
Sbjct: 265 VRWK-HGD--IDLTPENNIPIGKNVLRLEDVKQSGTYKCIGSSELG 307



 Score = 65.7 bits (153), Expect = 7e-09
 Identities = 47/190 (24%), Positives = 82/190 (43%), Gaps = 12/190 (6%)

Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHA-TAV 349
           D P I  +P    V  G +A F C A+G P P ++W      ++       DK    T+ 
Sbjct: 33  DAPRITTAPRDQKVMEGKIASFFCKASGNPAPEVYWKRGWKESL------HDKNETKTSN 86

Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAG--SSFVRGKLTVTSDDDRPP--PIITNGPS 405
               +VL ++ T        I C A +  G  ++    +L +  +++ P   P +   P 
Sbjct: 87  MPHGSVLRVDPTKWQKDETIIECVAESGIGHQAATATARLHIYRENEEPKGFPRLLETPE 146

Query: 406 NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKDLDKSDSGT 464
            +++      +  C+A   PEP + W  +   +  + +R  V   G+L +++   SD G 
Sbjct: 147 MRSVEKDRNFILKCSATGDPEPSVYWLKDNIPVDMSDKRIQVLPGGSLSIRNGQGSDEGK 206

Query: 465 YTCVASSRHG 474
           Y CVA + HG
Sbjct: 207 YECVAENIHG 216



 Score = 44.0 bits (99), Expect = 0.025
 Identities = 34/100 (34%), Positives = 50/100 (50%), Gaps = 7/100 (7%)

Query: 730 VPDGPPINIEM--FILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINT 787
           VP G P NI +  F  + T+  L+W+ P+++++ G  T Y VV + L    NK   + N 
Sbjct: 319 VPAGAPQNITIHPFGSSATSAKLQWNAPDIRIKQGDSTLYEVVYH-LRQDQNKEW-STNI 376

Query: 788 TVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYF 827
           T      +I  NL     Y  QI A T  G GP+S ++ F
Sbjct: 377 T---EEFIIFENLLPNSEYIFQIRAHTYKGPGPWSYQLPF 413


>UniRef50_P16621 Cluster: Tyrosine-protein phosphatase Lar
           precursor; n=37; cellular organisms|Rep:
           Tyrosine-protein phosphatase Lar precursor - Drosophila
           melanogaster (Fruit fly)
          Length = 2029

 Score =  116 bits (278), Expect = 5e-24
 Identities = 90/305 (29%), Positives = 142/305 (46%), Gaps = 27/305 (8%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPA- 63
           V +   P II +P +  V     A+  C A G P P+I W K G  V     R ++L   
Sbjct: 30  VDAAHPPEIIRKPQNQGVRVGGVASFYCAARGDPPPSIVWRKNGKKVSGTQSRYTVLEQP 89

Query: 64  GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE------FRLEPESK 117
           GG+  LR    R   D   Y C A N  G A S +ATL +    +           P ++
Sbjct: 90  GGISILRIEPVRAGRDDAPYECVAENGVGDAVSADATLTIYEGDKTPAGFPVITQGPGTR 149

Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR 177
               G TV++ C    G+P PN+YW KN QT +   + R  L DG  L I+++R+ D G+
Sbjct: 150 VIEVGHTVLMTC-KAIGNPTPNIYWIKN-QTKVDMSNPRYSLKDGF-LQIENSREEDQGK 206

Query: 178 YQCIARNAAGTRESAIATLKIHIK--PYLITGPEDVVAQT--GSSVTFQCRVGGDPLPDV 233
           Y+C+A N+ GT  S    L + ++  P   + P + +++   GS++   C   G P+P V
Sbjct: 207 YECVAENSMGTEHSKATNLYVKVRRVPPTFSRPPETISEVMLGSNLNLSCIAVGSPMPHV 266

Query: 234 LWRRSAGG----GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
            W + +        MP+GR        L+L N+   +   Y+C A +++G + +   + V
Sbjct: 267 KWMKGSEDLTPENEMPIGR------NVLQLINI--QESANYTCIAASTLGQIDSVSVVKV 318

Query: 290 YDPPS 294
              P+
Sbjct: 319 QSLPT 323



 Score =  111 bits (266), Expect = 1e-22
 Identities = 151/636 (23%), Positives = 250/636 (39%), Gaps = 94/636 (14%)

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS----L 257
           P +I  P++   + G   +F C   GDP P ++WR++    +    R  VL+       L
Sbjct: 36  PEIIRKPQNQGVRVGGVASFYCAARGDPPPSIVWRKNGKKVSGTQSRYTVLEQPGGISIL 95

Query: 258 RLDNVILA-DEGEYSCEAENSVG-AVSASGYLTVYDP-------PSINLSPNSVNVESGN 308
           R++ V    D+  Y C AEN VG AVSA   LT+Y+        P I   P +  +E G+
Sbjct: 96  RIEPVRAGRDDAPYECVAENGVGDAVSADATLTIYEGDKTPAGFPVITQGPGTRVIEVGH 155

Query: 309 VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
               TC A G P P ++W    N+T +   MS  +Y   ++ DG   +   +  + + + 
Sbjct: 156 TVLMTCKAIGNPTPNIYWIK--NQTKV--DMSNPRY---SLKDGFLQI---ENSREEDQG 205

Query: 369 TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN-QTLPIKSMAVFPCTAICTPEP 427
              C A N  G+   +    +     R PP  +  P     + + S     C A+ +P P
Sbjct: 206 KYECVAENSMGTEHSKAT-NLYVKVRRVPPTFSRPPETISEVMLGSNLNLSCIAVGSPMP 264

Query: 428 IIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
            + W    E L   +   +   G  VL+ ++  +S  YTC+A+S  G+        +DS 
Sbjct: 265 HVKWMKGSEDLTPENEMPI---GRNVLQLINIQESANYTCIAASTLGQ--------IDS- 312

Query: 488 INPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRET 547
                       V SLP  PT      VT TSV L WS     G   +  Y ++      
Sbjct: 313 -------VSVVKVQSLPTAPTDVQISEVTATSVRLEWSYK---GPEDLQYYVIQY----- 357

Query: 548 LSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
                 P+N+         +   +YVV++L P   Y F V   N+ G  GP     + T 
Sbjct: 358 -----KPKNANQAFSEISGIITMYYVVRALSPYTEYEFYVIAVNNIG-RGPPSAPATCTT 411

Query: 608 GDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNF--YYLEGLF 665
           G+        T + ++   RN          ++   + S T+ + WE        + G  
Sbjct: 412 GE--------TKMESAP--RN----------VQVRTLSSSTMVITWEPPETPNGQVTGYK 451

Query: 666 IYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFL--IPFYKKFEGKPSNSRV 723
           +Y+    N     + +   +S  V   E+T++ + T +  +   +  Y      P ++ V
Sbjct: 452 VYYTTNSN-----QPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAGPMSTPV 506

Query: 724 AQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMV 783
                      P N     +  T V L+W+ P    +N  I  Y +   W D  AN+   
Sbjct: 507 QVKAQQGVPSQPSNFRATDIGETAVTLQWTKPTHSSEN--IVHYELY--WNDTYANQ--- 559

Query: 784 AINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819
           A +  +  + +  +  L     Y + +AA +  G G
Sbjct: 560 AHHKRISNSEAYTLDGLYPDTLYYIWLAARSQRGEG 595



 Score = 80.6 bits (190), Expect = 2e-13
 Identities = 51/186 (27%), Positives = 76/186 (40%), Gaps = 7/186 (3%)

Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
           PP I   P +  V  G VA F C A G P P++ W   G +       ++ +Y       
Sbjct: 35  PPEIIRKPQNQGVRVGGVASFYCAARGDPPPSIVWRKNGKKV----SGTQSRYTVLEQPG 90

Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSF-VRGKLTVTSDDDRPP--PIITNGPSNQT 408
           G+++L I             C A N  G +      LT+   D  P   P+IT GP  + 
Sbjct: 91  GISILRIEPVRAGRDDAPYECVAENGVGDAVSADATLTIYEGDKTPAGFPVITQGPGTRV 150

Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468
           + +    +  C AI  P P I W      +  ++ R    DG L +++  + D G Y CV
Sbjct: 151 IEVGHTVLMTCKAIGNPTPNIYWIKNQTKVDMSNPRYSLKDGFLQIENSREEDQGKYECV 210

Query: 469 ASSRHG 474
           A +  G
Sbjct: 211 AENSMG 216



 Score = 66.1 bits (154), Expect = 6e-09
 Identities = 46/188 (24%), Positives = 90/188 (47%), Gaps = 10/188 (5%)

Query: 639 IEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLR 698
           ++ + + + +++L W       L+   I ++P +      E+  I+       + + +L 
Sbjct: 328 VQISEVTATSVRLEWSYKGPEDLQYYVIQYKPKNANQAFSEISGII----TMYYVVRALS 383

Query: 699 KYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQ 758
            YT+YEF++I       G PS      T +   +  P N+++  L+++T+ + W PPE  
Sbjct: 384 PYTEYEFYVIAVNNIGRGPPSAPATCTTGETKMESAPRNVQVRTLSSSTMVITWEPPE-- 441

Query: 759 LQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSL-IMTNLTSGVSYSVQIAAETIIG 817
             NG +TGY V   +    +N+   + N+ +   + L  ++ LT    Y+V++ A T +G
Sbjct: 442 TPNGQVTGYKV---YYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMG 498

Query: 818 LGPFSQKV 825
            GP S  V
Sbjct: 499 AGPMSTPV 506



 Score = 66.1 bits (154), Expect = 6e-09
 Identities = 51/189 (26%), Positives = 87/189 (46%), Gaps = 4/189 (2%)

Query: 639 IEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLD-NITIEYEMKTILHSNDVSGFEITSL 697
           I A    S TI L W         G  IY++     +  E +  T +  N ++   +  L
Sbjct: 617 ITAIATSSTTISLSWLPPPVERSNGRIIYYKVFFVEVGREDDEATTMTLN-MTSIVLDEL 675

Query: 698 RKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPEL 757
           +++T+Y+ +++      +G  S+  + +T +DVP G P +++   LN+T++H+ W PP  
Sbjct: 676 KRWTEYKIWVLAGTSVGDGPRSHPIILRTQEDVP-GDPQDVKATPLNSTSIHVSWKPPLE 734

Query: 758 QLQNGIITGYNVVVNWL-DVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETII 816
           + +NGII GY++    L D             V       +T L     YS+Q+AA T  
Sbjct: 735 KDRNGIIRGYHIHAQELRDEGKGFLNEPFKFDVVDTLEFNVTGLQPDTKYSIQVAALTRK 794

Query: 817 GLGPFSQKV 825
           G G  S  +
Sbjct: 795 GDGDRSAAI 803



 Score = 55.2 bits (127), Expect = 1e-05
 Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 4/134 (2%)

Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751
           + +  L   T Y  +L    ++ EG  +     +T   VP  PP NI     ++TT+ L 
Sbjct: 571 YTLDGLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQYVPGAPPRNITAIATSSTTISLS 630

Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811
           W PP ++  NG I  Y V      V   +      T     TS+++  L     Y + + 
Sbjct: 631 WLPPPVERSNGRIIYYKVFF----VEVGREDDEATTMTLNMTSIVLDELKRWTEYKIWVL 686

Query: 812 AETIIGLGPFSQKV 825
           A T +G GP S  +
Sbjct: 687 AGTSVGDGPRSHPI 700



 Score = 53.6 bits (123), Expect = 3e-05
 Identities = 34/105 (32%), Positives = 51/105 (48%), Gaps = 7/105 (6%)

Query: 722 RVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVN-WLDVPANK 780
           ++ QT +  P GPP NI +       + + W PP  + +NGIIT Y+V  +  +D     
Sbjct: 900 KIFQTPEGTPGGPPSNITIRFQTPDVLCVTWDPPTREHRNGIITRYDVQFHKKIDHGLGS 959

Query: 781 SMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
                N T+ +A   + TNL     Y  ++ A T  G GPFS K+
Sbjct: 960 ER---NMTLRKA---VFTNLEENTEYIFRVRAYTKQGAGPFSDKL 998



 Score = 45.6 bits (103), Expect = 0.008
 Identities = 35/140 (25%), Positives = 61/140 (43%), Gaps = 7/140 (5%)

Query: 688 DVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNT-T 746
           D   F +T L+  TKY   +    +K +G  S + V +T   VP  P +++++       
Sbjct: 769 DTLEFNVTGLQPDTKYSIQVAALTRKGDGDRSAAIVVKTPGGVPVRPTVSLKIMEREPIV 828

Query: 747 TVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSY 806
           ++ L+W  P      G + GY +     D    + M++      Q T     NL  GV Y
Sbjct: 829 SIELEWERPAQTY--GELRGYRLRWGVKDQALKEEMLS----GPQMTKKRFDNLERGVEY 882

Query: 807 SVQIAAETIIGLGPFSQKVY 826
             ++A    IG+G  + K++
Sbjct: 883 EFRVAGSNHIGIGQETVKIF 902



 Score = 41.5 bits (93), Expect = 0.14
 Identities = 38/144 (26%), Positives = 60/144 (41%), Gaps = 6/144 (4%)

Query: 695  TSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSP 754
            T+L + T+Y F +  + K+  G  S+  + +T  D+   P ++++    +  T  + W P
Sbjct: 971  TNLEENTEYIFRVRAYTKQGAGPFSDKLIVETERDMGRAP-MSLQAEATSEQTAEIWWEP 1029

Query: 755  PELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAET 814
                   G + GY +      V           TV    S  + NL     Y+V IAA  
Sbjct: 1030 VT---SRGKLLGYKIFYTMTAVEDLDDWQT--KTVGLTESADLVNLEKFAQYAVAIAARF 1084

Query: 815  IIGLGPFSQKVYFNIDSRSVGLDL 838
              GLG  S+KV   I    V L+L
Sbjct: 1085 KNGLGRLSEKVTVRIKPEDVPLNL 1108


>UniRef50_UPI00015A60B9 Cluster: UPI00015A60B9 related cluster; n=3;
            Danio rerio|Rep: UPI00015A60B9 UniRef100 entry - Danio
            rerio
          Length = 3050

 Score =  115 bits (277), Expect = 7e-24
 Identities = 131/527 (24%), Positives = 216/527 (40%), Gaps = 63/527 (11%)

Query: 121  QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRY 178
            +G  V +  L   G P+P +YW ++  T+       +   + GN  ++I+ A+++D G Y
Sbjct: 684  EGQEVTMSVLVT-GQPKPMLYWLRDRVTIKTGTRHIVQETEEGNFEMIIKSAQRSDTGVY 742

Query: 179  QCIARNAAGTRESAIATLKIHIKPY-----LITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233
             C   N  GT++     L++  +P      +I    DV+ + G +  F+C V G    DV
Sbjct: 743  TCKIINEYGTKQCE-GKLEVKARPVEPGLAIIRPVRDVMVKAGETALFECHVIGPQDTDV 801

Query: 234  LWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290
             W          L   K+  DG    L L++V   D G Y+C+   +   +++S  L V 
Sbjct: 802  DWLSDGKLIQPALLNCKMHFDGKRCRLLLNSVHEDDSGTYTCKLSTAKEELTSSAKLKVI 861

Query: 291  DP--PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWS-----VEGNRTI-IFPGMSRD 342
                P      + + V  G  ARF C  +G P P + WS     +E N  I I     R 
Sbjct: 862  ASIEPLFTRKLDVLEVIEGRNARFDCKVSGTPPPQVIWSHFDRPLEENEDIRILKEGGRH 921

Query: 343  KY---HATAVFDGV-TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398
                 H +   +G+ TV   N   +++    +       A SS +  KL         P 
Sbjct: 922  SLIISHVSNEDEGLYTVAARNSHGEDECAAELYVQEPRPAISSQI-AKLEKMPSIPEEPE 980

Query: 399  IITNGPSNQTLP--IKSM----------AVFPCTAICTPEPIIAWYFEGEALIQNHRRNV 446
            +  N     T+P  +K +          AV  C     P P I W+  G+ +     R +
Sbjct: 981  VPENEIERFTMPDFVKPLYDMDVVEGREAVLRCKVAGLPYPTITWFHNGKRIDSTEDRKM 1040

Query: 447  T---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSL 503
            T   +  +LV++ +  +  G Y CV S++ GK      L V              D+  L
Sbjct: 1041 TQFRDVHSLVVRCVCHAHGGVYKCVISNKVGKATCYSHLYV-------------TDI--L 1085

Query: 504  PGPPT-KPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
            P PP   P+  ++T  ++TLSW +  ++  S      +    ++ L        S  W +
Sbjct: 1086 PDPPDGAPVVESITGKTITLSWKKPKRLDPSIDPSSLMYAIQQQAL-------GSIQWTI 1138

Query: 563  IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
            IA  + QT Y + +L  G+ Y F V +  S   S PSP ++ + + D
Sbjct: 1139 IASCLKQTTYTISNLSKGVRYAFRVLSITSKAFSKPSPATEPMQLLD 1185



 Score = 77.8 bits (183), Expect = 2e-12
 Identities = 85/304 (27%), Positives = 128/304 (42%), Gaps = 26/304 (8%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
           E P  +    D +V   Q  T++    G P P + W +  V + + T   +       F 
Sbjct: 669 EPPAFLAVIGDQSVIEGQEVTMSVLVTGQPKPMLYWLRDRVTIKTGTRHIVQETEEGNFE 728

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL---EP-ESKQSAQGDTV 125
                   SD GVY C+  N YGT +     L V     E  L    P        G+T 
Sbjct: 729 MIIKSAQRSDTGVYTCKIINEYGT-KQCEGKLEVKARPVEPGLAIIRPVRDVMVKAGETA 787

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLL-FDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIA 182
           + EC    G  + +V W  +G+ +     + +MH  DG    L++    + D+G Y C  
Sbjct: 788 LFEC-HVIGPQDTDVDWLSDGKLIQPALLNCKMHF-DGKRCRLLLNSVHEDDSGTYTCKL 845

Query: 183 RNAAGTRESAIATLKI--HIKPYLITGPEDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSA 239
             A     S+ A LK+   I+P L T   DV+    G +  F C+V G P P V+W    
Sbjct: 846 STAKEELTSS-AKLKVIASIEP-LFTRKLDVLEVIEGRNARFDCKVSGTPPPQVIWSHF- 902

Query: 240 GGGNMPLGR---VKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP- 292
              + PL     +++L +G   SL + +V   DEG Y+  A NS G    +  L V +P 
Sbjct: 903 ---DRPLEENEDIRILKEGGRHSLIISHVSNEDEGLYTVAARNSHGEDECAAELYVQEPR 959

Query: 293 PSIN 296
           P+I+
Sbjct: 960 PAIS 963



 Score = 70.5 bits (165), Expect = 3e-10
 Identities = 78/318 (24%), Positives = 122/318 (38%), Gaps = 26/318 (8%)

Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR-VKVLDDGSLRL--DN 261
           + G + V+   G  VT    V G P P + W R            V+  ++G+  +   +
Sbjct: 676 VIGDQSVIE--GQEVTMSVLVTGQPKPMLYWLRDRVTIKTGTRHIVQETEEGNFEMIIKS 733

Query: 262 VILADEGEYSCEAENSVGAVSASGYLTV----YDPPSINLSP-NSVNVESGNVARFTCTA 316
              +D G Y+C+  N  G     G L V     +P    + P   V V++G  A F C  
Sbjct: 734 AQRSDTGVYTCKIINEYGTKQCEGKLEVKARPVEPGLAIIRPVRDVMVKAGETALFECHV 793

Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV-LTINDTDKNDSRNTIVCSAV 375
            G  +  + W  +G   +I P +   K H    FDG    L +N   ++DS  T  C   
Sbjct: 794 IGPQDTDVDWLSDGK--LIQPALLNCKMH----FDGKRCRLLLNSVHEDDS-GTYTCKLS 846

Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG 435
                     KL V +  +   P+ T       +     A F C    TP P + W    
Sbjct: 847 TAKEELTSSAKLKVIASIE---PLFTRKLDVLEVIEGRNARFDCKVSGTPPPQVIWSHFD 903

Query: 436 EALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
             L +N    +  +G   +L++  +   D G YT  A + HG+   +  L V  P  P I
Sbjct: 904 RPLEENEDIRILKEGGRHSLIISHVSNEDEGLYTVAARNSHGEDECAAELYVQEP-RPAI 962

Query: 493 HFFRAADVSSLPGPPTKP 510
              + A +  +P  P +P
Sbjct: 963 S-SQIAKLEKMPSIPEEP 979



 Score = 68.1 bits (159), Expect = 1e-09
 Identities = 49/158 (31%), Positives = 73/158 (46%), Gaps = 7/158 (4%)

Query: 139  NVYWKKNGQTLLFDGDSRMHLV----DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194
            +V WK+ G   L +      L     D   L +   + +D G+  CIA N  G+ +S + 
Sbjct: 1223 SVTWKRIGGVTLSNRPGLFELSMPDDDQHTLKLCKVKSSDVGQLTCIANNKYGS-DSCVL 1281

Query: 195  TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254
            TL++ + P   T  ED+    G +  F   V G P+PD+LW +     +       V DD
Sbjct: 1282 TLEMAVAPTFETIMEDLDVNVGETPRFAVVVEGKPVPDILWYKGDTLLSESSHFTFVYDD 1341

Query: 255  G--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290
               SL + N    D G Y+C A+N  G+VS    LTV+
Sbjct: 1342 NECSLVVLNTQADDSGVYTCTAKNLAGSVSCKAELTVH 1379



 Score = 55.2 bits (127), Expect = 1e-05
 Identities = 55/215 (25%), Positives = 87/215 (40%), Gaps = 14/215 (6%)

Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
           +PP+        +V  G     +   TG+P+P ++W  +  R  I  G    ++      
Sbjct: 669 EPPAFLAVIGDQSVIEGQEVTMSVLVTGQPKPMLYWLRD--RVTIKTGT---RHIVQETE 723

Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
           +G   + I    ++D+     C  +N  G+    GKL V +    P   I     +  + 
Sbjct: 724 EGNFEMIIKSAQRSDT-GVYTCKIINEYGTKQCEGKLEVKARPVEPGLAIIRPVRDVMVK 782

Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN--DGT---LVLKDLDKSDSGTY 465
               A+F C  I   +  + W  +G+ LIQ    N     DG    L+L  + + DSGTY
Sbjct: 783 AGETALFECHVIGPQDTDVDWLSDGK-LIQPALLNCKMHFDGKRCRLLLNSVHEDDSGTY 841

Query: 466 TCVASSRHGKYVWSGALLVDSPINPNIHFFRAADV 500
           TC  S+   +   S  L V + I P   F R  DV
Sbjct: 842 TCKLSTAKEELTSSAKLKVIASIEP--LFTRKLDV 874



 Score = 54.0 bits (124), Expect = 2e-05
 Identities = 55/195 (28%), Positives = 86/195 (44%), Gaps = 12/195 (6%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD---THRSILPAGGL 66
            EAP II++P  V +   QP ++        + ++ W + G + +S+        +P    
Sbjct: 1192 EAPVIIDKPDIVYMVEKQPLSITVTL-NHVNASVTWKRIGGVTLSNRPGLFELSMPDDDQ 1250

Query: 67   FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
              L+    +  SD G   C A N YG + S   TL +AV    F    E      G+T  
Sbjct: 1251 HTLKLCKVK-SSDVGQLTCIANNKYG-SDSCVLTLEMAV-APTFETIMEDLDVNVGETPR 1307

Query: 127  LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARN 184
               +   G P P++ W K G TLL +      + D    +LV+ + +  D+G Y C A+N
Sbjct: 1308 F-AVVVEGKPVPDILWYK-GDTLLSESSHFTFVYDDNECSLVVLNTQADDSGVYTCTAKN 1365

Query: 185  AAGTRESAIATLKIH 199
             AG+  S  A L +H
Sbjct: 1366 LAGS-VSCKAELTVH 1379



 Score = 53.6 bits (123), Expect = 3e-05
 Identities = 47/163 (28%), Positives = 73/163 (44%), Gaps = 14/163 (8%)

Query: 233  VLWRRSAGG--GNMP-LGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYL 287
            V W+R  G    N P L  + + DD   +L+L  V  +D G+ +C A N  G+ S    L
Sbjct: 1224 VTWKRIGGVTLSNRPGLFELSMPDDDQHTLKLCKVKSSDVGQLTCIANNKYGSDSCVLTL 1283

Query: 288  TVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
             +   P+       ++V  G   RF     G+P P + W  +G+  +       +  H T
Sbjct: 1284 EMAVAPTFETIMEDLDVNVGETPRFAVVVEGKPVPDILW-YKGDTLL------SESSHFT 1336

Query: 348  AVF-DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389
             V+ D    L + +T  +DS     C+A N AGS   + +LTV
Sbjct: 1337 FVYDDNECSLVVLNTQADDS-GVYTCTAKNLAGSVSCKAELTV 1378



 Score = 52.4 bits (120), Expect = 7e-05
 Identities = 30/83 (36%), Positives = 46/83 (55%), Gaps = 2/83 (2%)

Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRR-SAGGGNMPLGRVKVLDD-GSLRLDNVILAD 266
           +D VA TG+ V  +C + G PLP+V+W++ +    N P   VK+  +  SL +     +D
Sbjct: 540 QDTVASTGTEVLLKCIISGTPLPEVIWKKDNTEVKNSPTHVVKIEGERHSLLIKWTKPSD 599

Query: 267 EGEYSCEAENSVGAVSASGYLTV 289
            G Y+  A N VG VS+S  L +
Sbjct: 600 AGTYTVTAVNEVGEVSSSATLFI 622



 Score = 51.6 bits (118), Expect = 1e-04
 Identities = 30/76 (39%), Positives = 44/76 (57%), Gaps = 7/76 (9%)

Query: 121  QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV---DGGNLV-IQDARQTDAG 176
            +GD V L CLP  GSP P++ W K+ + L  + D RM+++   DG  L+ I    + DAG
Sbjct: 2388 EGDPVTLSCLPA-GSPHPHISWMKDKKPL--EIDPRMNMISCPDGRQLLMIMKTTKKDAG 2444

Query: 177  RYQCIARNAAGTRESA 192
             Y+C+A N   T  S+
Sbjct: 2445 LYECVAANPLATVTSS 2460



 Score = 40.7 bits (91), Expect = 0.24
 Identities = 23/83 (27%), Positives = 34/83 (40%), Gaps = 1/83 (1%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P  ++   D+ V   + A L C+  G P P I W+  G  + S   R +     +  L  
Sbjct: 992  PDFVKPLYDMDVVEGREAVLRCKVAGLPYPTITWFHNGKRIDSTEDRKMTQFRDVHSL-V 1050

Query: 72   THGRVHSDAGVYWCEATNSYGTA 94
                 H+  GVY C  +N  G A
Sbjct: 1051 VRCVCHAHGGVYKCVISNKVGKA 1073



 Score = 40.3 bits (90), Expect = 0.31
 Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 2/85 (2%)

Query: 37   GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
            G P P I WYKG  L+   +H + +       L   + +   D+GVY C A N  G+   
Sbjct: 1314 GKPVPDILWYKGDTLLSESSHFTFVYDDNECSLVVLNTQA-DDSGVYTCTAKNLAGSVSC 1372

Query: 97   R-NATLHVAVLREEFRLEPESKQSA 120
            +   T+H  +  ++++ +P   +++
Sbjct: 1373 KAELTVHTNITSKQYKDDPMEDEAS 1397



 Score = 39.9 bits (89), Expect = 0.41
 Identities = 36/106 (33%), Positives = 45/106 (42%), Gaps = 8/106 (7%)

Query: 3   DDYVTSGEAPY---IIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVV-SDTH 57
           D YV++GE P    + E PL  TVA       L C   G+P P + W K    V  S TH
Sbjct: 520 DSYVSAGEDPLEAPVFEFPLQDTVASTGTEVLLKCIISGTPLPEVIWKKDNTEVKNSPTH 579

Query: 58  RSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103
             ++   G            SDAG Y   A N  G   S +ATL +
Sbjct: 580 --VVKIEGERHSLLIKWTKPSDAGTYTVTAVNEVGEV-SSSATLFI 622



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 23/77 (29%), Positives = 30/77 (38%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
            D  +    P TL+C   GSP P I W K    +  D   +++       L         D
Sbjct: 2383 DHVLLEGDPVTLSCLPAGSPHPHISWMKDKKPLEIDPRMNMISCPDGRQLLMIMKTTKKD 2442

Query: 80   AGVYWCEATNSYGTARS 96
            AG+Y C A N   T  S
Sbjct: 2443 AGLYECVAANPLATVTS 2459



 Score = 37.1 bits (82), Expect = 2.9
 Identities = 30/95 (31%), Positives = 50/95 (52%), Gaps = 7/95 (7%)

Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVI 167
           F    +   ++ G  V+L+C+   G+P P V WKK+  T + +  + +  ++G   +L+I
Sbjct: 535 FEFPLQDTVASTGTEVLLKCIIS-GTPLPEVIWKKD-NTEVKNSPTHVVKIEGERHSLLI 592

Query: 168 QDARQTDAGRYQCIARNAAGTRESAIATLKIHIKP 202
           +  + +DAG Y   A N  G   S+ ATL   IKP
Sbjct: 593 KWTKPSDAGTYTVTAVNEVG-EVSSSATL--FIKP 624


>UniRef50_Q4RHM3 Cluster: Chromosome 19 SCAF15045, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 19 SCAF15045, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 1292

 Score =  115 bits (277), Expect = 7e-24
 Identities = 86/293 (29%), Positives = 136/293 (46%), Gaps = 21/293 (7%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGLFF 68
           AP+ I  P ++ +A ++   L CR GG P P I W+  GV +    + HR  +    +  
Sbjct: 567 APFWISAPRNLILAPNETGILTCRVGGDPKPKITWFINGVSMENAPEDHRRSVDGDTVIL 626

Query: 69  LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVL 127
                G     + VY C A+N +G   + NA ++V          P +  Q    +  +L
Sbjct: 627 SNVQSG----SSAVYQCNASNEFGYLMA-NAFVNVLAEAPRILTPPNQVYQVITNNPALL 681

Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
            C    GSP P + W K+ QT +  GD  + + + G L I  A+  ++G+Y CIA N  G
Sbjct: 682 HC-ASFGSPIPVITWFKDVQTSVKSGDPYV-IHENGTLEIHVAQLVNSGKYTCIATNNLG 739

Query: 188 TRESAI-------ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
            +E+ +       A L       ++  PE  V Q G S  F+C+V  DP  +P + W + 
Sbjct: 740 IKENHVFLEVKAGAFLSTSEPTRILKQPEYKVVQRGMSAAFECKVKHDPTLIPTMTWLKD 799

Query: 239 AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
           +  G +P     V+D  +L + +V   D+G Y+C    S+   SAS  LTV +
Sbjct: 800 S--GELPDDERFVVDADTLTIMDVTDRDKGTYTCFMNTSLDHDSASAVLTVVE 850



 Score = 79.8 bits (188), Expect = 4e-13
 Identities = 69/273 (25%), Positives = 103/273 (37%), Gaps = 16/273 (5%)

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSAGGGNMPLGRVKVLDDGSLRLD 260
           P+ I+ P +++     +    CRVGGDP P + W        N P    + +D  ++ L 
Sbjct: 568 PFWISAPRNLILAPNETGILTCRVGGDPKPKITWFINGVSMENAPEDHRRSVDGDTVILS 627

Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVY-DPPSINLSPNSV-NVESGNVARFTCTATG 318
           NV       Y C A N  G + A+ ++ V  + P I   PN V  V + N A   C + G
Sbjct: 628 NVQSGSSAVYQCNASNEFGYLMANAFVNVLAEAPRILTPPNQVYQVITNNPALLHCASFG 687

Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKY--HATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
            P P + W  +   ++     S D Y  H     +      +N           +    N
Sbjct: 688 SPIPVITWFKDVQTSV----KSGDPYVIHENGTLEIHVAQLVNSGKYTCIATNNLGIKEN 743

Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE--PIIAWYFE 434
           +       G    TS+  R    I   P  + +     A F C     P   P + W  +
Sbjct: 744 HVFLEVKAGAFLSTSEPTR----ILKQPEYKVVQRGMSAAFECKVKHDPTLIPTMTWLKD 799

Query: 435 GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
              L  + R  V  D TL + D+   D GTYTC
Sbjct: 800 SGELPDDERFVVDAD-TLTIMDVTDRDKGTYTC 831



 Score = 65.7 bits (153), Expect = 7e-09
 Identities = 44/172 (25%), Positives = 72/172 (41%), Gaps = 4/172 (2%)

Query: 15  IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGLFFLRAT 72
           ++ P D      +   ++C A G P P+  W + G    V  D+   + P  G   +  +
Sbjct: 228 LQSPKDYIFDPRENIVIHCEAKGKPHPSFSWTRNGTHFDVEKDSKVLMKPGSGTLVIDIS 287

Query: 73  HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP 132
             +  +  G Y C A N +GTA S    +  +      +   E+    +G ++VL+C PP
Sbjct: 288 GEKAEAYEGTYQCTAQNDHGTAVSNKIVIRQSRSPLWSKERNEAVVVQKGVSLVLQCRPP 347

Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIAR 183
            G P P ++W  N    L   D R+     G+L   +    D+   Y C AR
Sbjct: 348 AGLPPPVIFWMDNNFHRL-PLDKRVSQALNGDLYFSNVLPEDSRPDYICYAR 398



 Score = 59.7 bits (138), Expect = 5e-07
 Identities = 50/160 (31%), Positives = 73/160 (45%), Gaps = 10/160 (6%)

Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQ---DARQTDAGRY 178
           + +V+ C   +G P P+  W +NG     + DS++ +  G G LVI    +  +   G Y
Sbjct: 240 ENIVIHC-EAKGKPHPSFSWTRNGTHFDVEKDSKVLMKPGSGTLVIDISGEKAEAYEGTY 298

Query: 179 QCIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVLWR 236
           QC A+N  GT  S    ++    P +     E VV Q G S+  QCR   G P P + W 
Sbjct: 299 QCTAQNDHGTAVSNKIVIRQSRSPLWSKERNEAVVVQKGVSLVLQCRPPAGLPPPVIFWM 358

Query: 237 RSAGGGNMPLG-RVKVLDDGSLRLDNVILAD-EGEYSCEA 274
            +     +PL  RV    +G L   NV+  D   +Y C A
Sbjct: 359 DN-NFHRLPLDKRVSQALNGDLYFSNVLPEDSRPDYICYA 397



 Score = 53.2 bits (122), Expect = 4e-05
 Identities = 45/180 (25%), Positives = 81/180 (45%), Gaps = 16/180 (8%)

Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
           +P ++ +        TC   G P+P + W + G   +       D  H  +V DG TV+ 
Sbjct: 573 APRNLILAPNETGILTCRVGGDPKPKITWFING---VSMENAPED--HRRSV-DGDTVIL 626

Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMA 415
            N   ++ S     C+A N  G       + V ++    P I+T  P NQ   +   + A
Sbjct: 627 SNV--QSGSSAVYQCNASNEFGYLMANAFVNVLAE---APRILT--PPNQVYQVITNNPA 679

Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND-GTLVLKDLDKSDSGTYTCVASSRHG 474
           +  C +  +P P+I W+ + +  +++    V ++ GTL +      +SG YTC+A++  G
Sbjct: 680 LLHCASFGSPIPVITWFKDVQTSVKSGDPYVIHENGTLEIHVAQLVNSGKYTCIATNNLG 739



 Score = 50.8 bits (116), Expect = 2e-04
 Identities = 23/65 (35%), Positives = 37/65 (56%), Gaps = 3/65 (4%)

Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEA 274
           G ++  +C   G P PD+ W++   GG +P GRV +     +L++ +V+  D GEY C A
Sbjct: 462 GETLELECIAEGLPTPDISWQKD--GGELPSGRVSIQTYQKTLKISDVVETDAGEYRCTA 519

Query: 275 ENSVG 279
            N +G
Sbjct: 520 TNRLG 524



 Score = 50.4 bits (115), Expect = 3e-04
 Identities = 35/109 (32%), Positives = 51/109 (46%), Gaps = 7/109 (6%)

Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175
           +K   +G+T+ LEC+   G P P++ W+K+G  L   G   +       L I D  +TDA
Sbjct: 456 TKMVLRGETLELECIA-EGLPTPDISWQKDGGELP-SGRVSIQTYQK-TLKISDVVETDA 512

Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR 224
           G Y+C A N  GT    I       +P+       VV ++   V  QCR
Sbjct: 513 GEYRCTATNRLGTAHHIIQVTVKGRRPFW----RQVVEESPLRVGLQCR 557



 Score = 37.1 bits (82), Expect = 2.9
 Identities = 34/130 (26%), Positives = 51/130 (39%), Gaps = 8/130 (6%)

Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS--LRLD-- 260
           +  P+D +     ++   C   G P P   W R+    ++      ++  GS  L +D  
Sbjct: 228 LQSPKDYIFDPRENIVIHCEAKGKPHPSFSWTRNGTHFDVEKDSKVLMKPGSGTLVIDIS 287

Query: 261 -NVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSPN-SVNVESGNVARFTC-TA 316
                A EG Y C A+N  G AVS    +     P  +   N +V V+ G      C   
Sbjct: 288 GEKAEAYEGTYQCTAQNDHGTAVSNKIVIRQSRSPLWSKERNEAVVVQKGVSLVLQCRPP 347

Query: 317 TGRPEPTMFW 326
            G P P +FW
Sbjct: 348 AGLPPPVIFW 357



 Score = 36.7 bits (81), Expect = 3.9
 Identities = 19/56 (33%), Positives = 28/56 (50%)

Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
           C A   P P I+W  +G  L        T   TL + D+ ++D+G Y C A++R G
Sbjct: 469 CIAEGLPTPDISWQKDGGELPSGRVSIQTYQKTLKISDVVETDAGEYRCTATNRLG 524



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 29/77 (37%), Positives = 35/77 (45%), Gaps = 14/77 (18%)

Query: 23  VARHQPATLNCRAGGSPSPAIRWYK-GGVL----VVSDTHRSILPAGGLFFLRATHGRVH 77
           V R +   L C A G P+P I W K GG L    V   T++  L    +         V 
Sbjct: 459 VLRGETLELECIAEGLPTPDISWQKDGGELPSGRVSIQTYQKTLKISDV---------VE 509

Query: 78  SDAGVYWCEATNSYGTA 94
           +DAG Y C ATN  GTA
Sbjct: 510 TDAGEYRCTATNRLGTA 526


>UniRef50_UPI00015B5487 Cluster: PREDICTED: similar to leucine-rich
           repeats and immunoglobulin-like domains 3; n=1; Nasonia
           vitripennis|Rep: PREDICTED: similar to leucine-rich
           repeats and immunoglobulin-like domains 3 - Nasonia
           vitripennis
          Length = 957

 Score =  115 bits (276), Expect = 9e-24
 Identities = 81/292 (27%), Positives = 128/292 (43%), Gaps = 19/292 (6%)

Query: 113 EPESKQSAQGDTVVLECLPPRGSPEPNVY-WKKNGQTL---LFDGDSRMHLVDGGNLV-- 166
           EP+S+ S +G  V L+C     +  P ++ WK +   L       DS     DG  L   
Sbjct: 517 EPKSQLSIKGRNVTLKCRATSTADAPLIFTWKHDNLELRDRTLQMDSEPVFSDGITLASS 576

Query: 167 ---IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223
              + +    DAG+YQC+  N  GT  S  A + + + P     P D+    GS+   +C
Sbjct: 577 VLNLVNVTNADAGKYQCMVSNNYGTTYSGKAKISVQVYPSFTKKPHDIRVAAGSTARLEC 636

Query: 224 RVGGDPLPDVLWRRSAGGGNMPLGRV----KVLDDGSLRLDNVILADEGEYSCEAENSVG 279
              G P P + W++  GG + P  R     K+  D  L + NV  AD G YSC A+N  G
Sbjct: 637 SAEGLPSPQIAWQKD-GGNDFPAARERRMHKMPTDDVLFIINVKTADSGVYSCTAQNLAG 695

Query: 280 AVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGM 339
            ++A+  LT+ + PS      +  V +G      C A+G P P + W   G+     P  
Sbjct: 696 IITANATLTILETPSFVKPMENKEVIAGGSIVMECMASGSPRPQLSWRKNGS-----PLQ 750

Query: 340 SRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTS 391
           + +++  TA    + ++    +D       ++ S  N  G+S +  K   TS
Sbjct: 751 ATERHFFTAENQLLIIVNTVPSDAGTYECEMINSLGNETGASLLTIKAAPTS 802



 Score =  110 bits (264), Expect = 3e-22
 Identities = 84/293 (28%), Positives = 132/293 (45%), Gaps = 13/293 (4%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSP-SPAIRWYKGGVLVVSDTHRSI----LPAGGL 66
           P I+E+P      + +  TL CRA  +  +P I  +K   L + D    +    + + G+
Sbjct: 512 PRIVEEPKSQLSIKGRNVTLKCRATSTADAPLIFTWKHDNLELRDRTLQMDSEPVFSDGI 571

Query: 67  FFLRATHGRVH---SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
               +    V+   +DAG Y C  +N+YGT  S  A + V V    F  +P   + A G 
Sbjct: 572 TLASSVLNLVNVTNADAGKYQCMVSNNYGTTYSGKAKISVQVY-PSFTKKPHDIRVAAGS 630

Query: 124 TVVLECLPPRGSPEPNVYWKKN-GQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCI 181
           T  LEC    G P P + W+K+ G       + RMH +   + L I + +  D+G Y C 
Sbjct: 631 TARLEC-SAEGLPSPQIAWQKDGGNDFPAARERRMHKMPTDDVLFIINVKTADSGVYSCT 689

Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
           A+N AG   +A ATL I   P  +   E+     G S+  +C   G P P + WR++   
Sbjct: 690 AQNLAGI-ITANATLTILETPSFVKPMENKEVIAGGSIVMECMASGSPRPQLSWRKNGSP 748

Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
                      ++  L + N + +D G Y CE  NS+G  + +  LT+   P+
Sbjct: 749 LQATERHFFTAENQLLIIVNTVPSDAGTYECEMINSLGNETGASLLTIKAAPT 801



 Score = 89.4 bits (212), Expect = 5e-16
 Identities = 70/280 (25%), Positives = 111/280 (39%), Gaps = 24/280 (8%)

Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL--WRRS---AGGGNMPLGRVKVLDDG 255
           KP ++  P+  ++  G +VT +CR        ++  W+          + +    V  DG
Sbjct: 511 KPRIVEEPKSQLSIKGRNVTLKCRATSTADAPLIFTWKHDNLELRDRTLQMDSEPVFSDG 570

Query: 256 S------LRLDNVILADEGEYSCEAENSVGAV-SASGYLTVYDPPSINLSPNSVNVESGN 308
                  L L NV  AD G+Y C   N+ G   S    ++V   PS    P+ + V +G+
Sbjct: 571 ITLASSVLNLVNVTNADAGKYQCMVSNNYGTTYSGKAKISVQVYPSFTKKPHDIRVAAGS 630

Query: 309 VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
            AR  C+A G P P + W  +G     FP     + H     D + ++ +   D      
Sbjct: 631 TARLECSAEGLPSPQIAWQKDGGND--FPAARERRMHKMPTDDVLFIINVKTADSG---- 684

Query: 369 TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428
              C+A N AG       LT+        P+      N+ +      V  C A  +P P 
Sbjct: 685 VYSCTAQNLAGIITANATLTILETPSFVKPM-----ENKEVIAGGSIVMECMASGSPRPQ 739

Query: 429 IAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTC 467
           ++W   G  L    R   T +   L++ +   SD+GTY C
Sbjct: 740 LSWRKNGSPLQATERHFFTAENQLLIIVNTVPSDAGTYEC 779



 Score = 87.0 bits (206), Expect = 3e-15
 Identities = 66/219 (30%), Positives = 101/219 (46%), Gaps = 14/219 (6%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG---VLVVSDTHRSILPAGGLFF 68
           P   ++P D+ VA    A L C A G PSP I W K G        +     +P   + F
Sbjct: 615 PSFTKKPHDIRVAAGSTARLECSAEGLPSPQIAWQKDGGNDFPAARERRMHKMPTDDVLF 674

Query: 69  LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVL 127
           +        +D+GVY C A N  G   + NATL   +L     ++P E+K+   G ++V+
Sbjct: 675 IINVK---TADSGVYSCTAQNLAGII-TANATL--TILETPSFVKPMENKEVIAGGSIVM 728

Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
           EC+   GSP P + W+KNG  L    +      +   L+I +   +DAG Y+C   N+ G
Sbjct: 729 ECM-ASGSPRPQLSWRKNGSPLQAT-ERHFFTAENQLLIIVNTVPSDAGTYECEMINSLG 786

Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVG 226
             E+  + L I   P  +   +D++     +V   C VG
Sbjct: 787 -NETGASLLTIKAAPTSVVNEDDMLGLIIITVVC-CAVG 823



 Score = 39.9 bits (89), Expect = 0.41
 Identities = 26/83 (31%), Positives = 33/83 (39%), Gaps = 3/83 (3%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
           E P  ++   +  V       + C A GSP P + W K G   +  T R    A     +
Sbjct: 707 ETPSFVKPMENKEVIAGGSIVMECMASGSPRPQLSWRKNG-SPLQATERHFFTAENQLLI 765

Query: 70  RATHGRVHSDAGVYWCEATNSYG 92
                 V SDAG Y CE  NS G
Sbjct: 766 IV--NTVPSDAGTYECEMINSLG 786



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 47/194 (24%), Positives = 76/194 (39%), Gaps = 16/194 (8%)

Query: 290 YDPPSINLSPNSVNVESGNVARFTCTATGRPE-PTMFWSVEGNRTIIFPGMSRDKYHATA 348
           +  P I   P S     G      C AT   + P +F     N  +    +  D   +  
Sbjct: 509 FPKPRIVEEPKSQLSIKGRNVTLKCRATSTADAPLIFTWKHDNLELRDRTLQMD---SEP 565

Query: 349 VF-DGVTVLT--INDTD-KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404
           VF DG+T+ +  +N  +  N       C   N  G+++  GK  ++    +  P  T  P
Sbjct: 566 VFSDGITLASSVLNLVNVTNADAGKYQCMVSNNYGTTY-SGKAKISV---QVYPSFTKKP 621

Query: 405 SNQTLPIKSMAVFPCTAICTPEPIIAWYFEG----EALIQNHRRNVTNDGTLVLKDLDKS 460
            +  +   S A   C+A   P P IAW  +G     A  +     +  D  L + ++  +
Sbjct: 622 HDIRVAAGSTARLECSAEGLPSPQIAWQKDGGNDFPAARERRMHKMPTDDVLFIINVKTA 681

Query: 461 DSGTYTCVASSRHG 474
           DSG Y+C A +  G
Sbjct: 682 DSGVYSCTAQNLAG 695


>UniRef50_UPI00015A3FB5 Cluster: hypothetical protein LOC553690;
           n=3; Danio rerio|Rep: hypothetical protein LOC553690 -
           Danio rerio
          Length = 981

 Score =  115 bits (276), Expect = 9e-24
 Identities = 74/283 (26%), Positives = 128/283 (45%), Gaps = 14/283 (4%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTH-----RSILPAGGL 66
           P  + +P D+ V +++ A  +C+    P PA+ WY    LV + +      R  + + G 
Sbjct: 190 PQPLVKPEDLVVMKNEEAVFHCQFTAEPMPAVEWYHENELVANKSRTGHFIRVFILSNGS 249

Query: 67  FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
             +     R   + G+Y C A    G   S  A+L +A + +   +  +S+  +      
Sbjct: 250 LLITQVKQR---NTGLYKCVAQGPRGPPVSLEASLRIAEIED--MMAKQSRVFSADSLER 304

Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
           + C  P G P+P V+W++ GQ +    D       G +L+       D+G Y C A+N A
Sbjct: 305 VTCRAPYGHPQPEVWWERAGQRV---PDHGRVFQKGHDLIFSPTHGEDSGIYTCFAQNKA 361

Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
           G ++  + T+ +  KP  +  P D   + G +    C    +P P V W R+    +   
Sbjct: 362 GQKKQEL-TVTVATKPEWVQKPVDSQLEEGRAGFLHCHTRANPEPQVTWYRNLQPISAED 420

Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
            R K+  +G+LR++NV + D   YSCE+    G V+A   + V
Sbjct: 421 VRFKLFSNGTLRINNVEVYDGHMYSCESRTEAGRVNAQARVFV 463



 Score =  102 bits (245), Expect = 5e-20
 Identities = 128/499 (25%), Positives = 201/499 (40%), Gaps = 42/499 (8%)

Query: 16  EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75
           ++P        + A L C        +  W + G   V+++ R  L  G L F       
Sbjct: 3   KEPKPQDALHGRSAMLRCEVNDPQGVSYSWIQNGE-PVTNSERRFLDGGNLKFTAIDRTL 61

Query: 76  VHSDAGVYWCEAT-NSYGTA-RSRNATLHVAVLRE-EFRLE-PESKQSAQGDT-VVLECL 130
              D+G + C A+ NS G   R+   + ++  L      L+ PES    Q  + V+L C 
Sbjct: 62  ---DSGNFQCIASKNSTGEEERTAETSFNIKWLESGAVSLKSPESVAEIQSSSQVILRCN 118

Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG-TR 189
              G P P   W K+G T + + + +++  +  ++ + +A   D G Y C A+NAAG   
Sbjct: 119 ID-GYPRPTNRWFKDG-TQITEKNYKINNKER-SVTLLNASPDDNGLYHCCAKNAAGQVC 175

Query: 190 ESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW--RRSAGGGNMP 245
            S   TL I  K  P  +  PED+V        F C+   +P+P V W            
Sbjct: 176 SSDNFTLNIIDKSFPQPLVKPEDLVVMKNEEAVFHCQFTAEPMPAVEWYHENELVANKSR 235

Query: 246 LG---RVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNS 301
            G   RV +L +GSL +  V   + G Y C A+   G  VS    L + +   +    + 
Sbjct: 236 TGHFIRVFILSNGSLLITQVKQRNTGLYKCVAQGPRGPPVSLEASLRIAEIEDMMAKQSR 295

Query: 302 VNVESGNVARFTCTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
           V   + ++ R TC A  G P+P ++W   G R    P   R       VF     L  + 
Sbjct: 296 V-FSADSLERVTCRAPYGHPQPEVWWERAGQRV---PDHGR-------VFQKGHDLIFSP 344

Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
           T   DS     C A N AG    + +LTVT       P     P +  L         C 
Sbjct: 345 THGEDS-GIYTCFAQNKAGQK--KQELTVTV---ATKPEWVQKPVDSQLEEGRAGFLHCH 398

Query: 421 AICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479
               PEP + WY   + +  ++ R  + ++GTL + +++  D   Y+C + +  G+    
Sbjct: 399 TRANPEPQVTWYRNLQPISAEDVRFKLFSNGTLRINNVEVYDGHMYSCESRTEAGRVNAQ 458

Query: 480 GA--LLVDSPINPNIHFFR 496
               +L      P IH+ R
Sbjct: 459 ARVFVLAKGRQTPTIHWMR 477



 Score = 80.6 bits (190), Expect = 2e-13
 Identities = 93/381 (24%), Positives = 148/381 (38%), Gaps = 33/381 (8%)

Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVY-WKKNGQTLLFDGDSRMHLVDGGNLVIQ 168
           F  EP+ + +  G + +L C      P+   Y W +NG+ +    +S    +DGGNL   
Sbjct: 1   FTKEPKPQDALHGRSAMLRC--EVNDPQGVSYSWIQNGEPVT---NSERRFLDGGNLKFT 55

Query: 169 DARQT-DAGRYQCIARNAAGTRESAIATLKIHIK-----PYLITGPEDVV-AQTGSSVTF 221
              +T D+G +QCIA   +   E   A    +IK        +  PE V   Q+ S V  
Sbjct: 56  AIDRTLDSGNFQCIASKNSTGEEERTAETSFNIKWLESGAVSLKSPESVAEIQSSSQVIL 115

Query: 222 QCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVGA 280
           +C + G P P   W +   G  +     K+ + + S+ L N    D G Y C A+N+ G 
Sbjct: 116 RCNIDGYPRPTNRWFKD--GTQITEKNYKINNKERSVTLLNASPDDNGLYHCCAKNAAGQ 173

Query: 281 VSASGYLT--VYDP--PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF 336
           V +S   T  + D   P   + P  + V     A F C  T  P P + W  E N  +  
Sbjct: 174 VCSSDNFTLNIIDKSFPQPLVKPEDLVVMKNEEAVFHCQFTAEPMPAVEWYHE-NELVAN 232

Query: 337 PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF-VRGKLTVTSDDDR 395
              +        + +G  ++T     K  +     C A    G    +   L +   +D 
Sbjct: 233 KSRTGHFIRVFILSNGSLLIT---QVKQRNTGLYKCVAQGPRGPPVSLEASLRIAEIED- 288

Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTA-ICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVL 454
                     ++     S+    C A    P+P + W   G+  + +H R       L+ 
Sbjct: 289 -----MMAKQSRVFSADSLERVTCRAPYGHPQPEVWWERAGQR-VPDHGRVFQKGHDLIF 342

Query: 455 KDLDKSDSGTYTCVASSRHGK 475
                 DSG YTC A ++ G+
Sbjct: 343 SPTHGEDSGIYTCFAQNKAGQ 363



 Score = 60.5 bits (140), Expect = 3e-07
 Identities = 36/93 (38%), Positives = 47/93 (50%), Gaps = 3/93 (3%)

Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
           F+L+PE+    QG T VL C    G P P + WKK  +  L  G SR   +  G+LVI D
Sbjct: 510 FKLKPENTTVYQGHTAVLHC-QATGDPPPFIQWKKKDK-FLEAGKSRFQKMANGSLVIHD 567

Query: 170 ARQTDAGRYQCIARNAAGTRESAIATLKIHIKP 202
               D G Y CIA N+     ++ A L +  KP
Sbjct: 568 VSTEDTGSYTCIAGNSCNIAHTS-AELYVVEKP 599



 Score = 48.8 bits (111), Expect = 9e-04
 Identities = 25/86 (29%), Positives = 38/86 (44%)

Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267
           PE+     G +    C+  GDP P + W++          R + + +GSL + +V   D 
Sbjct: 514 PENTTVYQGHTAVLHCQATGDPPPFIQWKKKDKFLEAGKSRFQKMANGSLVIHDVSTEDT 573

Query: 268 GEYSCEAENSVGAVSASGYLTVYDPP 293
           G Y+C A NS      S  L V + P
Sbjct: 574 GSYTCIAGNSCNIAHTSAELYVVEKP 599



 Score = 42.3 bits (95), Expect = 0.078
 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 1/69 (1%)

Query: 404 PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKDLDKSDS 462
           P N T+     AV  C A   P P I W  + + L     R     +G+LV+ D+   D+
Sbjct: 514 PENTTVYQGHTAVLHCQATGDPPPFIQWKKKDKFLEAGKSRFQKMANGSLVIHDVSTEDT 573

Query: 463 GTYTCVASS 471
           G+YTC+A +
Sbjct: 574 GSYTCIAGN 582



 Score = 40.3 bits (90), Expect = 0.31
 Identities = 30/101 (29%), Positives = 44/101 (43%), Gaps = 4/101 (3%)

Query: 17  QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV 76
           +P + TV +   A L+C+A G P P I+W K    + +   R    A G   +   H   
Sbjct: 513 KPENTTVYQGHTAVLHCQATGDPPPFIQWKKKDKFLEAGKSRFQKMANGSLVI---HDVS 569

Query: 77  HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK 117
             D G Y C A NS   A + +A L+V     +  L  + K
Sbjct: 570 TEDTGSYTCIAGNSCNIAHT-SAELYVVEKPVQHSLSDDEK 609



 Score = 37.1 bits (82), Expect = 2.9
 Identities = 27/101 (26%), Positives = 45/101 (44%), Gaps = 6/101 (5%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
           VT    P  +++P+D  +   +   L+C    +P P + WY+    + ++  R  L + G
Sbjct: 370 VTVATKPEWVQKPVDSQLEEGRAGFLHCHTRANPEPQVTWYRNLQPISAEDVRFKLFSNG 429

Query: 66  LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVL 106
              LR  +  V+ D  +Y CE+    G     NA   V VL
Sbjct: 430 T--LRINNVEVY-DGHMYSCESRTEAGRV---NAQARVFVL 464


>UniRef50_Q7KSE9 Cluster: CG31190-PB, isoform B; n=4; Diptera|Rep:
           CG31190-PB, isoform B - Drosophila melanogaster (Fruit
           fly)
          Length = 2046

 Score =  115 bits (276), Expect = 9e-24
 Identities = 122/492 (24%), Positives = 196/492 (39%), Gaps = 41/492 (8%)

Query: 29  ATLNCRAGGSPSPAIRWY--KGGVLVVSDTHRSILPAGGLFF--LRATHGRVHSDAGVYW 84
           A + C A GSP P + W    G +       R I   G L F    A + R       Y 
Sbjct: 56  AQVTCTAHGSPPPLVTWVLRDGSLATQVPGLRKISGNGTLHFPPFLAQYYRTDVHEATYR 115

Query: 85  CEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC-LPPRGSPEPNVY-W 142
           C A+N  GT  SRN  +H AV+R +F +  E+ +   G++ +++C +P    P   V  W
Sbjct: 116 CRASNEAGTVLSRNVQVH-AVVRRQFHVHVENTEVYLGNSALIKCAIPEYVRPYVRVASW 174

Query: 143 KKNGQTLLFD----GDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAA-GTRESAIAT- 195
            +  + LL D        + L   G+L ++  R  D   ++ C+  N   G R+ + A  
Sbjct: 175 HRGEEILLPDLSDVAGRYVVLAASGDLYVRSVRSEDGLMKFSCLVTNTLNGERQRSDAVM 234

Query: 196 -----LKIHIKPYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRR---SAGGGNMPL 246
                L  ++ P     P  ++  + G+ V   C + G+P P   W R   SA    +P 
Sbjct: 235 LQVKELSKNLAPRTTQKPVMEIHVERGNDVHLPCNIQGNPFPIFTWYRVSDSAALYPIPS 294

Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
            +  +L    L + N    D G++ C+A N  G       L+V    S+++ P    V S
Sbjct: 295 SQRVILSRTLLLIKNADERDAGKWICQASNQFGEQRIEIRLSVNSYVSVHILPQVQIVNS 354

Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
           G  A F CT TG     + W   G        ++  + +    F   + L + +  + D 
Sbjct: 355 GGTANFNCTTTGSAIDAIDWLHNGKPLQANNALTTGRDNIR--FLSKSSLLVQNVGRRD- 411

Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
           R    C   N   S+    +L +    D  P +I         P   +    C+A  +P 
Sbjct: 412 RGVYQCLVENQRASAQAMAELKL---GDTVPELIYTFIEQNVRP-GPLISLKCSASGSPP 467

Query: 427 PIIAWYFEGEALIQ---NHR----RNVTNDGTLV----LKDLDKSDSGTYTCVASSRHGK 475
           P  AW  + + ++    +HR    + V   G ++    +  +   D G Y CVAS+  G 
Sbjct: 468 PQFAWLLDSQPIMDVSLHHRFAIGQFVDMSGDVISHLNISHVRPDDGGLYKCVASNSMGS 527

Query: 476 YVWSGALLVDSP 487
              S  L V  P
Sbjct: 528 VQHSARLNVYGP 539



 Score =  101 bits (242), Expect = 1e-19
 Identities = 120/502 (23%), Positives = 200/502 (39%), Gaps = 50/502 (9%)

Query: 11  APYIIEQP-LDVTVARHQPATLNCRAGGSPSPAIRWYK---GGVLVVSDTHRSILPAGGL 66
           AP   ++P +++ V R     L C   G+P P   WY+      L    + + ++ +  L
Sbjct: 245 APRTTQKPVMEIHVERGNDVHLPCNIQGNPFPIFTWYRVSDSAALYPIPSSQRVILSRTL 304

Query: 67  FFLRATHGRVHSDAGVYWCEATNSYGTARSR---NATLHVAVLREEFRLEPESKQSAQGD 123
             ++    R   DAG + C+A+N +G  R     +   +V+V      + P+ +    G 
Sbjct: 305 LLIKNADER---DAGKWICQASNQFGEQRIEIRLSVNSYVSV-----HILPQVQIVNSGG 356

Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTL-----LFDGDSRMHLVDGGNLVIQDARQTDAGRY 178
           T    C    GS    + W  NG+ L     L  G   +  +   +L++Q+  + D G Y
Sbjct: 357 TANFNC-TTTGSAIDAIDWLHNGKPLQANNALTTGRDNIRFLSKSSLLVQNVGRRDRGVY 415

Query: 179 QCIARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
           QC+  N   + + A+A LK+    P LI    +   + G  ++ +C   G P P   W  
Sbjct: 416 QCLVENQRASAQ-AMAELKLGDTVPELIYTFIEQNVRPGPLISLKCSASGSPPPQFAWLL 474

Query: 238 SAG-------GGNMPLGR-VKVLDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYL 287
            +             +G+ V +  D    L + +V   D G Y C A NS+G+V  S  L
Sbjct: 475 DSQPIMDVSLHHRFAIGQFVDMSGDVISHLNISHVRPDDGGLYKCVASNSMGSVQHSARL 534

Query: 288 TVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
            VY PP +  +   +   +G      C   G P   + W  + ++ +     + + Y   
Sbjct: 535 NVYGPPYVR-AIGPIKAVAGEDIIVHCPFAGYPVEQIRWE-KAHQEL----TTSNHYELA 588

Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG-KLTVTSDDDRPPPIITNGPSN 406
           +V DG   L I + +    +    C   + AG    R  +L V S     PP+I      
Sbjct: 589 SVADG-GQLVIKNVEPGRDQGIYTCIVRSRAGEEARRDMQLNVNS-----PPVIEPFKFP 642

Query: 407 QTLPIKSMAVFPCTAICTPEPI-IAWYFEGEAL---IQNHRRNVTNDGTLVLKDLDKSDS 462
           + L     A   C       PI  +W  +  ++   +Q   +       LV KD+    S
Sbjct: 643 KNLQEGGRAQITCAVSSGDMPIYFSWKKDDSSIPSSLQITEKKEEFYSLLVFKDISARHS 702

Query: 463 GTYTCVASSRHGKYVWSGALLV 484
           G YTC AS+   K  ++  L V
Sbjct: 703 GKYTCYASNAAAKVNYTAELQV 724



 Score = 90.6 bits (215), Expect = 2e-16
 Identities = 82/310 (26%), Positives = 126/310 (40%), Gaps = 18/310 (5%)

Query: 30  TLNCRAGGSPSPAIRWYKGG--VLVVSDTHR----SILPAGG--LFFLRATHGRVHSDAG 81
           +L C A GSP P   W      ++ VS  HR      +   G  +  L  +H R   D G
Sbjct: 457 SLKCSASGSPPPQFAWLLDSQPIMDVSLHHRFAIGQFVDMSGDVISHLNISHVRP-DDGG 515

Query: 82  VYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVY 141
           +Y C A+NS G+ +  +A L+V        + P   ++  G+ +++ C P  G P   + 
Sbjct: 516 LYKCVASNSMGSVQ-HSARLNVYGPPYVRAIGPI--KAVAGEDIIVHC-PFAGYPVEQIR 571

Query: 142 WKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQ-TDAGRYQCIARNAAGTRESAIATLKIH 199
           W+K  Q L       +  V DGG LVI++     D G Y CI R+ AG        L ++
Sbjct: 572 WEKAHQELTTSNHYELASVADGGQLVIKNVEPGRDQGIYTCIVRSRAGEEARRDMQLNVN 631

Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL-WRR--SAGGGNMPLGRVKVLDDGS 256
             P +         Q G      C V    +P    W++  S+   ++ +   K      
Sbjct: 632 SPPVIEPFKFPKNLQEGGRAQITCAVSSGDMPIYFSWKKDDSSIPSSLQITEKKEEFYSL 691

Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316
           L   ++     G+Y+C A N+   V+ +  L V   P     P    +  GN     C A
Sbjct: 692 LVFKDISARHSGKYTCYASNAAAKVNYTAELQVRVAPRWRYEPMDTAIMLGNTISINCEA 751

Query: 317 TGRPEPTMFW 326
            G P PT+ W
Sbjct: 752 EGYPIPTITW 761



 Score = 66.9 bits (156), Expect = 3e-09
 Identities = 55/223 (24%), Positives = 92/223 (41%), Gaps = 21/223 (9%)

Query: 31  LNCRAGGSPSPAIRWYKGGVLVVSDTH---RSILPAGGLFFLRATHGRVHSDAGVYWCEA 87
           ++C   G P   IRW K    + +  H    S+   G L       GR   D G+Y C  
Sbjct: 558 VHCPFAGYPVEQIRWEKAHQELTTSNHYELASVADGGQLVIKNVEPGR---DQGIYTCIV 614

Query: 88  TNSYGTARSRNATLHV--AVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
            +  G    R+  L+V    + E F+  P++ Q  +G    + C    G       WKK+
Sbjct: 615 RSRAGEEARRDMQLNVNSPPVIEPFKF-PKNLQ--EGGRAQITCAVSSGDMPIYFSWKKD 671

Query: 146 GQTLLFDGDSRMHLVDGGN-----LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
             ++     S + + +        LV +D     +G+Y C A NAA  + +  A L++ +
Sbjct: 672 DSSI----PSSLQITEKKEEFYSLLVFKDISARHSGKYTCYASNAAA-KVNYTAELQVRV 726

Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
            P     P D     G++++  C   G P+P + W +  G G+
Sbjct: 727 APRWRYEPMDTAIMLGNTISINCEAEGYPIPTITWFKGQGKGS 769



 Score = 57.2 bits (132), Expect = 3e-06
 Identities = 47/167 (28%), Positives = 74/167 (44%), Gaps = 14/167 (8%)

Query: 673  NITIEYEMKTILHSNDVSGFEITS-----LRKYTKYEFFLIPFYKKFEGKPSNSRVAQTL 727
            NI     + + L S  VSG+  T      LRKY++Y   +        G  S +    T 
Sbjct: 1043 NINFISVVNSSLKSTIVSGWATTKATLRGLRKYSRYAVTIRAMNSFGSGPWSAAIFGTTA 1102

Query: 728  DDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNV----VVNWLDVPANKSMV 783
            + VP+  P N+    L++ ++ + W  P LQ   GII GY +    +V+ +D PA    +
Sbjct: 1103 EGVPEAAPQNVNCTALSSQSLKISWLEPPLQFHGGIIQGYKILYRPIVHQIDFPAK---L 1159

Query: 784  AINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNID 830
             I  T +  T L    L    +YS+++ A T  G G  S  ++   D
Sbjct: 1160 EIKRTSNLETYL--HTLHKASNYSIRVLAYTATGDGLASHPLFCQTD 1204



 Score = 55.2 bits (127), Expect = 1e-05
 Identities = 94/424 (22%), Positives = 157/424 (37%), Gaps = 32/424 (7%)

Query: 157 MHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTG 216
           M L++   LV++ A    A     +A     T    + T  +   P L+ G +     TG
Sbjct: 1   MSLLEPPCLVLEKALLLGALLLAVLATPLLATSGLRVPTFLLEPAPRLLFGND-----TG 55

Query: 217 SSVTFQCRVGGDPLPDVLW-RRSAGGGNMPLGRVKVLDDGSLRLDNVIL------ADEGE 269
           + VT  C   G P P V W  R         G  K+  +G+L     +         E  
Sbjct: 56  AQVT--CTAHGSPPPLVTWVLRDGSLATQVPGLRKISGNGTLHFPPFLAQYYRTDVHEAT 113

Query: 270 YSCEAENSVGAV-SASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTM-FWS 327
           Y C A N  G V S +  +        ++   +  V  GN A   C       P +   S
Sbjct: 114 YRCRASNEAGTVLSRNVQVHAVVRRQFHVHVENTEVYLGNSALIKCAIPEYVRPYVRVAS 173

Query: 328 VEGNRTIIFPGMS--RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385
                 I+ P +S    +Y   A    + V ++   D     + +V + +N         
Sbjct: 174 WHRGEEILLPDLSDVAGRYVVLAASGDLYVRSVRSEDGLMKFSCLVTNTLNGERQRSDAV 233

Query: 386 KLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWY--FEGEAL--IQ 440
            L V        P  T  P  +    +   V  PC     P PI  WY   +  AL  I 
Sbjct: 234 MLQVKELSKNLAPRTTQKPVMEIHVERGNDVHLPCNIQGNPFPIFTWYRVSDSAALYPIP 293

Query: 441 NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADV 500
           + +R + +   L++K+ D+ D+G + C AS++ G+      L V+S +  ++H      +
Sbjct: 294 SSQRVILSRTLLLIKNADERDAGKWICQASNQFGEQRIEIRLSVNSYV--SVHILPQVQI 351

Query: 501 SSLPGPPTKPITHNVTDTSV-TLSWSQNNK-IGSSSILGY---QVEVFSRETLSGNNTPR 555
            +  G  T       T +++  + W  N K + +++ L      +   S+ +L   N  R
Sbjct: 352 VNSGG--TANFNCTTTGSAIDAIDWLHNGKPLQANNALTTGRDNIRFLSKSSLLVQNVGR 409

Query: 556 NSRG 559
             RG
Sbjct: 410 RDRG 413



 Score = 49.2 bits (112), Expect = 7e-04
 Identities = 45/187 (24%), Positives = 82/187 (43%), Gaps = 11/187 (5%)

Query: 639  IEATPIDSKTIKLMW--EILNFY--YLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEI 694
            +  T + S+++K+ W    L F+   ++G  I +RP+ +  I++  K  +         +
Sbjct: 1113 VNCTALSSQSLKISWLEPPLQFHGGIIQGYKILYRPIVH-QIDFPAKLEIKRTSNLETYL 1171

Query: 695  TSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSP 754
             +L K + Y   ++ +    +G  S+    QT DDVPD P   I+   L   ++ + W  
Sbjct: 1172 HTLHKASNYSIRVLAYTATGDGLASHPLFCQTDDDVPDAPAA-IKAAALTADSILISWLT 1230

Query: 755  PELQLQNGIITGYNVVVN--WLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAA 812
            P  + +NGII+ Y V          A   MV ++   +  T     +L     Y   ++A
Sbjct: 1231 P--KNRNGIISHYTVYSREAGRKGQAKTHMVRVDENGYPVT-FESRSLAENQMYEFWVSA 1287

Query: 813  ETIIGLG 819
             T +G G
Sbjct: 1288 STSVGEG 1294



 Score = 42.7 bits (96), Expect = 0.059
 Identities = 50/225 (22%), Positives = 89/225 (39%), Gaps = 14/225 (6%)

Query: 83   YWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTVVLECLPPRGSPEPNV 140
            +W  A+ S G     +        R   R+    +  + A G  +VLECL   G+P P  
Sbjct: 1283 FWVSASTSVGEGEPTSVIAQATNTRAPARIASFGQVVRKAVGTGLVLECLAV-GNPTPRA 1341

Query: 141  YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
             W    + + F       + + GNL I     + +G Y C A N  G+ E  I    I +
Sbjct: 1342 RWLTRDRPVTFS--PFYEVTNEGNLKIHRVEGSLSGNYTCTANNLFGSDE--IQYQVIAM 1397

Query: 201  KPYLITGPEDVVAQTGSS---VTFQC-RVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS 256
            KP   + P+ +V    +    V++     GG PL          G +  +  + + ++ +
Sbjct: 1398 KP--PSAPQIIVQYASADSIRVSWDAPDDGGAPLQGYTISYHTAGESWSITEL-LPENNA 1454

Query: 257  LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
              +  +   ++      A N VG+  AS  + V+     + +PN+
Sbjct: 1455 FTISGLKCGNQYIIKMSAHNMVGSGVASEEINVWTKGKASQAPNA 1499



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 19/59 (32%), Positives = 28/59 (47%)

Query: 416  VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
            V  C A+  P P   W      +  +    VTN+G L +  ++ S SG YTC A++  G
Sbjct: 1328 VLECLAVGNPTPRARWLTRDRPVTFSPFYEVTNEGNLKIHRVEGSLSGNYTCTANNLFG 1386



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 26/111 (23%), Positives = 48/111 (43%), Gaps = 8/111 (7%)

Query: 723  VAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNV-------VVNWLD 775
            V +T ++ P   P N+++     + + + W  P  +  NG + GY V        +N++ 
Sbjct: 989  VLKTQEEAPTEAPSNVQVQTGGESELIVTWQIPPRESWNGELIGYTVNCSEEKQNINFIS 1048

Query: 776  VPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVY 826
            V  N S+ +   +    T   +  L     Y+V I A    G GP+S  ++
Sbjct: 1049 V-VNSSLKSTIVSGWATTKATLRGLRKYSRYAVTIRAMNSFGSGPWSAAIF 1098



 Score = 35.5 bits (78), Expect = 8.9
 Identities = 14/38 (36%), Positives = 20/38 (52%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG 48
           AP    +P+D  +      ++NC A G P P I W+KG
Sbjct: 727 APRWRYEPMDTAIMLGNTISINCEAEGYPIPTITWFKG 764


>UniRef50_Q6IDE9 Cluster: LP21844p; n=2; Sophophora|Rep: LP21844p -
           Drosophila melanogaster (Fruit fly)
          Length = 1006

 Score =  115 bits (276), Expect = 9e-24
 Identities = 122/492 (24%), Positives = 196/492 (39%), Gaps = 41/492 (8%)

Query: 29  ATLNCRAGGSPSPAIRWY--KGGVLVVSDTHRSILPAGGLFF--LRATHGRVHSDAGVYW 84
           A + C A GSP P + W    G +       R I   G L F    A + R       Y 
Sbjct: 56  AQVTCTAHGSPPPLVTWVLRDGSLATQVPGLRKISGNGTLHFPPFLAQYYRTDVHEATYR 115

Query: 85  CEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC-LPPRGSPEPNVY-W 142
           C A+N  GT  SRN  +H AV+R +F +  E+ +   G++ +++C +P    P   V  W
Sbjct: 116 CRASNEAGTVLSRNVQVH-AVVRRQFHVHVENTEVYLGNSALIKCAIPEYVRPYVRVASW 174

Query: 143 KKNGQTLLFD----GDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAA-GTRESAIAT- 195
            +  + LL D        + L   G+L ++  R  D   ++ C+  N   G R+ + A  
Sbjct: 175 HRGEEILLPDLSDVAGRYVVLAASGDLYVRSVRSEDGLMKFSCLVTNTLNGERQRSDAVM 234

Query: 196 -----LKIHIKPYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRR---SAGGGNMPL 246
                L  ++ P     P  ++  + G+ V   C + G+P P   W R   SA    +P 
Sbjct: 235 LQVKELSKNLAPRTTQKPVMEIHVERGNDVHLPCNIQGNPFPIFTWYRVSDSAALYPIPS 294

Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
            +  +L    L + N    D G++ C+A N  G       L+V    S+++ P    V S
Sbjct: 295 SQRVILSRTLLLIKNADERDAGKWICQASNQFGEQRIEIRLSVNSYVSVHILPQVQIVNS 354

Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
           G  A F CT TG     + W   G        ++  + +    F   + L + +  + D 
Sbjct: 355 GGTANFNCTTTGSAIDAIDWLHNGKPLQANNALTTGRDNIR--FLSKSSLLVQNVGRRD- 411

Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
           R    C   N   S+    +L +    D  P +I         P   +    C+A  +P 
Sbjct: 412 RGVYQCLVENQRASAQAMAELKL---GDTVPELIYTFIEQNVRP-GPLISLKCSASGSPP 467

Query: 427 PIIAWYFEGEALIQ---NHR----RNVTNDGTLV----LKDLDKSDSGTYTCVASSRHGK 475
           P  AW  + + ++    +HR    + V   G ++    +  +   D G Y CVAS+  G 
Sbjct: 468 PQFAWLLDSQPIMDVSLHHRFAIGQFVDMSGDVISHLNISHVRPDDGGLYKCVASNSMGS 527

Query: 476 YVWSGALLVDSP 487
              S  L V  P
Sbjct: 528 VQHSARLNVYGP 539



 Score =  101 bits (242), Expect = 1e-19
 Identities = 120/502 (23%), Positives = 200/502 (39%), Gaps = 50/502 (9%)

Query: 11  APYIIEQP-LDVTVARHQPATLNCRAGGSPSPAIRWYK---GGVLVVSDTHRSILPAGGL 66
           AP   ++P +++ V R     L C   G+P P   WY+      L    + + ++ +  L
Sbjct: 245 APRTTQKPVMEIHVERGNDVHLPCNIQGNPFPIFTWYRVSDSAALYPIPSSQRVILSRTL 304

Query: 67  FFLRATHGRVHSDAGVYWCEATNSYGTARSR---NATLHVAVLREEFRLEPESKQSAQGD 123
             ++    R   DAG + C+A+N +G  R     +   +V+V      + P+ +    G 
Sbjct: 305 LLIKNADER---DAGKWICQASNQFGEQRIEIRLSVNSYVSV-----HILPQVQIVNSGG 356

Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTL-----LFDGDSRMHLVDGGNLVIQDARQTDAGRY 178
           T    C    GS    + W  NG+ L     L  G   +  +   +L++Q+  + D G Y
Sbjct: 357 TANFNC-TTTGSAIDAIDWLHNGKPLQANNALTTGRDNIRFLSKSSLLVQNVGRRDRGVY 415

Query: 179 QCIARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
           QC+  N   + + A+A LK+    P LI    +   + G  ++ +C   G P P   W  
Sbjct: 416 QCLVENQRASAQ-AMAELKLGDTVPELIYTFIEQNVRPGPLISLKCSASGSPPPQFAWLL 474

Query: 238 SAG-------GGNMPLGR-VKVLDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYL 287
            +             +G+ V +  D    L + +V   D G Y C A NS+G+V  S  L
Sbjct: 475 DSQPIMDVSLHHRFAIGQFVDMSGDVISHLNISHVRPDDGGLYKCVASNSMGSVQHSARL 534

Query: 288 TVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
            VY PP +  +   +   +G      C   G P   + W  + ++ +     + + Y   
Sbjct: 535 NVYGPPYVR-AIGPIKAVAGEDIIVHCPFAGYPVEQIRWE-KAHQEL----TTSNHYELA 588

Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG-KLTVTSDDDRPPPIITNGPSN 406
           +V DG   L I + +    +    C   + AG    R  +L V S     PP+I      
Sbjct: 589 SVADG-GQLVIKNVEPGRDQGIYTCIVRSRAGEEARRDMQLNVNS-----PPVIEPFKFP 642

Query: 407 QTLPIKSMAVFPCTAICTPEPI-IAWYFEGEAL---IQNHRRNVTNDGTLVLKDLDKSDS 462
           + L     A   C       PI  +W  +  ++   +Q   +       LV KD+    S
Sbjct: 643 KNLQEGGRAQITCAVSSGDMPIYFSWKKDDSSIPSSLQITEKKEEFYSLLVFKDISARHS 702

Query: 463 GTYTCVASSRHGKYVWSGALLV 484
           G YTC AS+   K  ++  L V
Sbjct: 703 GKYTCYASNAAAKVNYTAELQV 724



 Score = 99.1 bits (236), Expect = 6e-19
 Identities = 118/469 (25%), Positives = 184/469 (39%), Gaps = 44/469 (9%)

Query: 30  TLNCRAGGSPSPAIRWYKGG--VLVVSDTHR----SILPAGG--LFFLRATHGRVHSDAG 81
           +L C A GSP P   W      ++ VS  HR      +   G  +  L  +H R   D G
Sbjct: 457 SLKCSASGSPPPQFAWLLDSQPIMDVSLHHRFAIGQFVDMSGDVISHLNISHVRP-DDGG 515

Query: 82  VYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVY 141
           +Y C A+NS G+ +  +A L+V        + P   ++  G+ +++ C P  G P   + 
Sbjct: 516 LYKCVASNSMGSVQ-HSARLNVYGPPYVRAIGPI--KAVAGEDIIVHC-PFAGYPVEQIR 571

Query: 142 WKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQ-TDAGRYQCIARNAAGTRESAIATLKIH 199
           W+K  Q L       +  V DGG LVI++     D G Y CI R+ AG        L ++
Sbjct: 572 WEKAHQELTTSNHYELASVADGGQLVIKNVEPGRDQGIYTCIVRSRAGEEARRDMQLNVN 631

Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL-WRR--SAGGGNMPLGRVKVLDDGS 256
             P +         Q G      C V    +P    W++  S+   ++ +   K      
Sbjct: 632 SPPVIEPFKFPKNLQEGGRAQITCAVSSGDMPIYFSWKKDDSSIPSSLQITEKKEEFYSL 691

Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316
           L   ++     G+Y+C A N+   V+ +  L V   P     P    +  GN     C A
Sbjct: 692 LVFKDISARHSGKYTCYASNAAAKVNYTAELQVRVAPRWRYEPMDTAIMLGNTISINCEA 751

Query: 317 TGRPEPTMFW-SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
            G P PT+ W   +G  +  F  +S  + H+         L +N    ND     +C A 
Sbjct: 752 EGYPIPTITWFKGQGKGSKDFKPLSM-RNHS---------LLLNLATDNDE-GYYMCQAT 800

Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAW-YF 433
           N  G+   +      ++  R      N  S +  P+       C A    EPI I W   
Sbjct: 801 NEIGAGLKKTIRINVNEPARFEQSARNISSRRNDPV----TLDCHAK-GDEPITIGWTQN 855

Query: 434 EGEALIQNHRRNVTN-------DGTLVLKDLDKSDSGTYTCVASSRHGK 475
            G   + N R ++         D  L +   D+ DSG Y C+A + +G+
Sbjct: 856 NGRIDLNNFRFSIAEMKTEKGVDSQLTIGHSDRHDSGVYRCIAENPYGR 904



 Score = 93.1 bits (221), Expect = 4e-17
 Identities = 94/378 (24%), Positives = 152/378 (40%), Gaps = 27/378 (7%)

Query: 31  LNCRAGGSPSPAIRWYKGGVLVVSDTH---RSILPAGGLFFLRATHGRVHSDAGVYWCEA 87
           ++C   G P   IRW K    + +  H    S+   G L       GR   D G+Y C  
Sbjct: 558 VHCPFAGYPVEQIRWEKAHQELTTSNHYELASVADGGQLVIKNVEPGR---DQGIYTCIV 614

Query: 88  TNSYGTARSRNATLHV--AVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
            +  G    R+  L+V    + E F+  P++ Q  +G    + C    G       WKK+
Sbjct: 615 RSRAGEEARRDMQLNVNSPPVIEPFKF-PKNLQ--EGGRAQITCAVSSGDMPIYFSWKKD 671

Query: 146 GQTLLFDGDSRMHLVDGGN-----LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
             ++     S + + +        LV +D     +G+Y C A NAA  + +  A L++ +
Sbjct: 672 DSSI----PSSLQITEKKEEFYSLLVFKDISARHSGKYTCYASNAAA-KVNYTAELQVRV 726

Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLD 260
            P     P D     G++++  C   G P+P + W +  G G+     +  + + SL L+
Sbjct: 727 APRWRYEPMDTAIMLGNTISINCEAEGYPIPTITWFKGQGKGSKDFKPLS-MRNHSLLLN 785

Query: 261 NVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGR 319
                DEG Y C+A N +GA +  +  + V +P     S  +++    +     C A G 
Sbjct: 786 LATDNDEGYYMCQATNEIGAGLKKTIRINVNEPARFEQSARNISSRRNDPVTLDCHAKGD 845

Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV-TVLTINDTDKNDSRNTIVCSAVNYA 378
              T+ W+    R  I     R          GV + LTI  +D++DS     C A N  
Sbjct: 846 EPITIGWTQNNGR--IDLNNFRFSIAEMKTEKGVDSQLTIGHSDRHDS-GVYRCIAENPY 902

Query: 379 GSSFVRGKLTVTSDDDRP 396
           G +     L V    D P
Sbjct: 903 GRAEQIIFLAVQERPDTP 920



 Score = 89.0 bits (211), Expect = 7e-16
 Identities = 126/548 (22%), Positives = 217/548 (39%), Gaps = 55/548 (10%)

Query: 29  ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS----DAGVYW 84
           A  NC   GS   AI W   G  + ++   +      + FL  +   V +    D GVY 
Sbjct: 358 ANFNCTTTGSAIDAIDWLHNGKPLQANNALTT-GRDNIRFLSKSSLLVQNVGRRDRGVYQ 416

Query: 85  CEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK 144
           C   N   +A++  A L +     E       +    G  + L+C    GSP P   W  
Sbjct: 417 CLVENQRASAQAM-AELKLGDTVPELIYTFIEQNVRPGPLISLKC-SASGSPPPQFAWLL 474

Query: 145 NGQTLLFDGDSRMH-------LVD-GGNLV----IQDARQTDAGRYQCIARNAAGTRESA 192
           + Q ++   D  +H        VD  G+++    I   R  D G Y+C+A N+ G+ + +
Sbjct: 475 DSQPIM---DVSLHHRFAIGQFVDMSGDVISHLNISHVRPDDGGLYKCVASNSMGSVQHS 531

Query: 193 IATLKIHIKPYL-ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPLGRV 249
            A L ++  PY+   GP   VA  G  +   C   G P+  + W ++      +      
Sbjct: 532 -ARLNVYGPPYVRAIGPIKAVA--GEDIIVHCPFAGYPVEQIRWEKAHQELTTSNHYELA 588

Query: 250 KVLDDGSLRLDNVILA-DEGEYSCEAENSVGAVSASGY-LTVYDPPSINLSPNSVNVESG 307
            V D G L + NV    D+G Y+C   +  G  +     L V  PP I       N++ G
Sbjct: 589 SVADGGQLVIKNVEPGRDQGIYTCIVRSRAGEEARRDMQLNVNSPPVIEPFKFPKNLQEG 648

Query: 308 NVARFTCTATGRPEPTMF-WSVEGNR--TIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
             A+ TC  +    P  F W  + +   + +     ++++++  VF  ++        ++
Sbjct: 649 GRAQITCAVSSGDMPIYFSWKKDDSSIPSSLQITEKKEEFYSLLVFKDISA-------RH 701

Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
             + T  C A N A       +L V     R  P     P +  + + +     C A   
Sbjct: 702 SGKYT--CYASNAAAKVNYTAELQV-----RVAPRWRYEPMDTAIMLGNTISINCEAEGY 754

Query: 425 PEPIIAWYFEGEALIQNHRRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
           P P I W F+G+       + ++  + +L+L     +D G Y C A++  G  +      
Sbjct: 755 PIPTITW-FKGQGKGSKDFKPLSMRNHSLLLNLATDNDEGYYMCQATNEIGAGLKK---T 810

Query: 484 VDSPINPNIHFFRAA-DVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEV 542
           +   +N    F ++A ++SS    P     H   D  +T+ W+QNN  G   +  ++  +
Sbjct: 811 IRINVNEPARFEQSARNISSRRNDPVTLDCHAKGDEPITIGWTQNN--GRIDLNNFRFSI 868

Query: 543 FSRETLSG 550
              +T  G
Sbjct: 869 AEMKTEKG 876



 Score = 62.5 bits (145), Expect = 7e-08
 Identities = 52/191 (27%), Positives = 78/191 (40%), Gaps = 16/191 (8%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
           AP    +P+D  +      ++NC A G P P I W+KG      D     +    L    
Sbjct: 727 APRWRYEPMDTAIMLGNTISINCEAEGYPIPTITWFKGQGKGSKDFKPLSMRNHSLLLNL 786

Query: 71  ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTVVLE 128
           AT     +D G Y C+ATN  G    +   ++V    E  R E  ++   S + D V L+
Sbjct: 787 AT----DNDEGYYMCQATNEIGAGLKKTIRINV---NEPARFEQSARNISSRRNDPVTLD 839

Query: 129 CLPPRGSPEPNVYWKKNGQTLLFD----GDSRMHLVDG--GNLVIQDARQTDAGRYQCIA 182
           C   +G     + W +N   +  +      + M    G    L I  + + D+G Y+CIA
Sbjct: 840 C-HAKGDEPITIGWTQNNGRIDLNNFRFSIAEMKTEKGVDSQLTIGHSDRHDSGVYRCIA 898

Query: 183 RNAAGTRESAI 193
            N  G  E  I
Sbjct: 899 ENPYGRAEQII 909



 Score = 55.2 bits (127), Expect = 1e-05
 Identities = 94/424 (22%), Positives = 157/424 (37%), Gaps = 32/424 (7%)

Query: 157 MHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTG 216
           M L++   LV++ A    A     +A     T    + T  +   P L+ G +     TG
Sbjct: 1   MSLLEPPCLVLEKALLLGALLLAVLATPLLATSGLRVPTFLLEPAPRLLFGND-----TG 55

Query: 217 SSVTFQCRVGGDPLPDVLW-RRSAGGGNMPLGRVKVLDDGSLRLDNVIL------ADEGE 269
           + VT  C   G P P V W  R         G  K+  +G+L     +         E  
Sbjct: 56  AQVT--CTAHGSPPPLVTWVLRDGSLATQVPGLRKISGNGTLHFPPFLAQYYRTDVHEAT 113

Query: 270 YSCEAENSVGAV-SASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTM-FWS 327
           Y C A N  G V S +  +        ++   +  V  GN A   C       P +   S
Sbjct: 114 YRCRASNEAGTVLSRNVQVHAVVRRQFHVHVENTEVYLGNSALIKCAIPEYVRPYVRVAS 173

Query: 328 VEGNRTIIFPGMS--RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385
                 I+ P +S    +Y   A    + V ++   D     + +V + +N         
Sbjct: 174 WHRGEEILLPDLSDVAGRYVVLAASGDLYVRSVRSEDGLMKFSCLVTNTLNGERQRSDAV 233

Query: 386 KLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWY--FEGEAL--IQ 440
            L V        P  T  P  +    +   V  PC     P PI  WY   +  AL  I 
Sbjct: 234 MLQVKELSKNLAPRTTQKPVMEIHVERGNDVHLPCNIQGNPFPIFTWYRVSDSAALYPIP 293

Query: 441 NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADV 500
           + +R + +   L++K+ D+ D+G + C AS++ G+      L V+S +  ++H      +
Sbjct: 294 SSQRVILSRTLLLIKNADERDAGKWICQASNQFGEQRIEIRLSVNSYV--SVHILPQVQI 351

Query: 501 SSLPGPPTKPITHNVTDTSV-TLSWSQNNK-IGSSSILGY---QVEVFSRETLSGNNTPR 555
            +  G  T       T +++  + W  N K + +++ L      +   S+ +L   N  R
Sbjct: 352 VNSGG--TANFNCTTTGSAIDAIDWLHNGKPLQANNALTTGRDNIRFLSKSSLLVQNVGR 409

Query: 556 NSRG 559
             RG
Sbjct: 410 RDRG 413


>UniRef50_UPI0000E468FC Cluster: PREDICTED: similar to KLG; n=3;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           KLG - Strongylocentrotus purpuratus
          Length = 1013

 Score =  114 bits (275), Expect = 1e-23
 Identities = 110/402 (27%), Positives = 171/402 (42%), Gaps = 43/402 (10%)

Query: 79  DAGVYWC---EATNSYGTARSRNATLHVAVLREEFRLE---PESKQSAQ-GDTVVLECLP 131
           DAG Y C    ++ +     S  A ++V  + EE R++   P   +  + G  V L C  
Sbjct: 55  DAGQYRCVVEPSSTAEAPMSSDPANVNVTWISEELRVQLNRPNLPEDVEEGGKVTLICRA 114

Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
             G+P P V W  + QT +  G +    + G  L I+ A   D+G Y C+A N AG+  S
Sbjct: 115 S-GNPVPMVTWYHD-QTPVVAGSNVD--ISGTRLKIKSATPLDSGIYSCMATNVAGSMPS 170

Query: 192 AIATLKIHI----KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW-RRSAGGGNMPL 246
               ++ +I     P +   P D +   G S+ F C+  GDP P V W   S  GG +P 
Sbjct: 171 T-ENVQFNIVDSNTPVVEVAPTDAIRVLGDSIMFHCQFSGDPTPPVEWYTTSKAGGEIPP 229

Query: 247 GRVK-------VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
             +        ++ +GSL L N+   DEGE+ C  ++  G   AS  LT+    ++N  P
Sbjct: 230 QLMNDTETGTYIIGNGSLSLANLTAGDEGEFQCVCDSPHGRPFASARLTI---ATVNPLP 286

Query: 300 N--SVNVESGNVARFTCT-----ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
              +  +  G+     C+       G P P++ W     R +   G    K     V + 
Sbjct: 287 EFEAQLIPEGDTKTINCSYPAGDVGGIPTPSIHWLKPSLREVPLDGT---KTKRVRVEEQ 343

Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
             +L  +   K+D  N   C + N AG +    K+ V +      P IT  P +  +  +
Sbjct: 344 KNLLVFDPIKKSDEGN-YTCVSSNMAGETTQILKVVVAT-----APKITTRPVDVHIRER 397

Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVL 454
             A   C A  TP P I+W F    +       V+ DG+LV+
Sbjct: 398 EEATLRCNATGTPTPTISWTFGTRDITNKQGIEVSADGSLVI 439



 Score =  104 bits (250), Expect = 1e-20
 Identities = 119/487 (24%), Positives = 205/487 (42%), Gaps = 66/487 (13%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWY----KGGVL---VVSDTHR 58
           +     P +   P D           +C+  G P+P + WY     GG +   +++DT  
Sbjct: 178 IVDSNTPVVEVAPTDAIRVLGDSIMFHCQFSGDPTPPVEWYTTSKAGGEIPPQLMNDTET 237

Query: 59  S--ILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPES 116
              I+  G L     T G    D G + C   + +G   + +A L +A +      E E+
Sbjct: 238 GTYIIGNGSLSLANLTAG----DEGEFQCVCDSPHGRPFA-SARLTIATVNP--LPEFEA 290

Query: 117 KQSAQGDTVVLECLPPRGS----PEPNVYW-KKNGQTLLFDG--DSRMHLVDGGNLVIQD 169
           +   +GDT  + C  P G     P P+++W K + + +  DG    R+ + +  NL++ D
Sbjct: 291 QLIPEGDTKTINCSYPAGDVGGIPTPSIHWLKPSLREVPLDGTKTKRVRVEEQKNLLVFD 350

Query: 170 -ARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228
             +++D G Y C++ N AG   + I  + +   P + T P DV  +     T +C   G 
Sbjct: 351 PIKKSDEGNYTCVSSNMAG-ETTQILKVVVATAPKITTRPVDVHIREREEATLRCNATGT 409

Query: 229 PLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
           P P + W           G ++V  DGSL +++                  A++    + 
Sbjct: 410 PTPTISWTFGTRDITNKQG-IEVSADGSLVINS------------------AMTRHNAIL 450

Query: 289 VYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
            ++P  I ++    +++ G + R  C AT   +P + W  +G   II  G   D  H + 
Sbjct: 451 KFNPRPIAVT----SLDRGEMNRLVCHATASIQPFIAWHKQG---II--GTWPD--HISE 499

Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408
              G  VL  N  + +D+  T +C     A +   R   TV  D    P  +     N T
Sbjct: 500 PNSG--VLQFNPAEASDA-GTYIC----IASTGLERINTTVRIDVVVKPKFVI--IPNNT 550

Query: 409 LPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
           +  +  ++   CTA   PEP I W  +       H  ++ N GTL+++++  +D+G Y C
Sbjct: 551 IGFEGYSLKIDCTAHGDPEPTITWISKPIMNYPEHFTHLPN-GTLIIQEVHANDAGRYQC 609

Query: 468 VASSRHG 474
           +A S  G
Sbjct: 610 IAGSDAG 616



 Score =  101 bits (243), Expect = 9e-20
 Identities = 90/325 (27%), Positives = 143/325 (44%), Gaps = 30/325 (9%)

Query: 30  TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
           TL CRA G+P P + WY     VV+ ++  I  +G    +++       D+G+Y C ATN
Sbjct: 109 TLICRASGNPVPMVTWYHDQTPVVAGSNVDI--SGTRLKIKSA---TPLDSGIYSCMATN 163

Query: 90  SYGTARS-RNATLHVAVLREEF-RLEPESKQSAQGDTVVLECLPPRGSPEPNVYW----K 143
             G+  S  N   ++         + P       GD+++  C    G P P V W    K
Sbjct: 164 VAGSMPSTENVQFNIVDSNTPVVEVAPTDAIRVLGDSIMFHC-QFSGDPTPPVEWYTTSK 222

Query: 144 KNGQT---LLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
             G+    L+ D ++  +++  G+L + +    D G +QC+  +  G R  A A L I  
Sbjct: 223 AGGEIPPQLMNDTETGTYIIGNGSLSLANLTAGDEGEFQCVCDSPHG-RPFASARLTIAT 281

Query: 201 KPYLITGPEDVVAQTGSSVTFQCR-----VGGDPLPDVLWRRSAGGGNMPLG-----RVK 250
              L      ++ + G + T  C      VGG P P + W + +    +PL      RV+
Sbjct: 282 VNPLPEFEAQLIPE-GDTKTINCSYPAGDVGGIPTPSIHWLKPSLR-EVPLDGTKTKRVR 339

Query: 251 VLDDGSLRL-DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309
           V +  +L + D +  +DEG Y+C + N  G  +    + V   P I   P  V++     
Sbjct: 340 VEEQKNLLVFDPIKKSDEGNYTCVSSNMAGETTQILKVVVATAPKITTRPVDVHIREREE 399

Query: 310 ARFTCTATGRPEPTMFWSVEGNRTI 334
           A   C ATG P PT+ W+  G R I
Sbjct: 400 ATLRCNATGTPTPTISWTF-GTRDI 423



 Score = 77.8 bits (183), Expect = 2e-12
 Identities = 88/382 (23%), Positives = 155/382 (40%), Gaps = 43/382 (11%)

Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
           +G +++L C   +     NV +      +  +  SR+ +    +L I D  + DAG+Y+C
Sbjct: 5   EGTSIILSCEVDQAE---NVVFSWTLNNVPVEDSSRIFMDTSNSLKIGDVSREDAGQYRC 61

Query: 181 IARNAAGTRESAIATLKIHIKPYLITG-----------PEDVVAQTGSSVTFQCRVGGDP 229
           +   ++ T E+ +++   ++    I+            PEDV  + G  VT  CR  G+P
Sbjct: 62  VVEPSS-TAEAPMSSDPANVNVTWISEELRVQLNRPNLPEDV--EEGGKVTLICRASGNP 118

Query: 230 LPDVLWRRS----AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASG 285
           +P V W         G N+ +   +      L++ +    D G YSC A N  G++ ++ 
Sbjct: 119 VPMVTWYHDQTPVVAGSNVDISGTR------LKIKSATPLDSGIYSCMATNVAGSMPSTE 172

Query: 286 YL--TVYDP--PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRT-IIFPGMS 340
            +   + D   P + ++P       G+   F C  +G P P + W         I P + 
Sbjct: 173 NVQFNIVDSNTPVVEVAPTDAIRVLGDSIMFHCQFSGDPTPPVEWYTTSKAGGEIPPQLM 232

Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII 400
            D    T +    ++   N T  ++     VC + +  G  F   +LT+ + +  P    
Sbjct: 233 NDTETGTYIIGNGSLSLANLTAGDEGEFQCVCDSPH--GRPFASARLTIATVNPLPEFEA 290

Query: 401 TNGPSNQTLPIKSMAVFPCTAIC-TPEPIIAWYFEGEALI-----QNHRRNVTNDGTLVL 454
              P   T  I     +P   +   P P I W       +     +  R  V     L++
Sbjct: 291 QLIPEGDTKTINCS--YPAGDVGGIPTPSIHWLKPSLREVPLDGTKTKRVRVEEQKNLLV 348

Query: 455 KD-LDKSDSGTYTCVASSRHGK 475
            D + KSD G YTCV+S+  G+
Sbjct: 349 FDPIKKSDEGNYTCVSSNMAGE 370



 Score = 75.8 bits (178), Expect = 7e-12
 Identities = 64/202 (31%), Positives = 99/202 (49%), Gaps = 14/202 (6%)

Query: 17  QPLDVT-VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75
           +P+ VT + R +   L C A  S  P I W+K G++     H S   +G L F  A    
Sbjct: 455 RPIAVTSLDRGEMNRLVCHATASIQPFIAWHKQGIIGTWPDHISEPNSGVLQFNPAEA-- 512

Query: 76  VHSDAGVYWCEATNSYGTARSRNATLHV-AVLREEFRLEPESKQSAQGDTVVLECLPPRG 134
             SDAG Y C A  S G  R  N T+ +  V++ +F + P +    +G ++ ++C    G
Sbjct: 513 --SDAGTYICIA--STGLERI-NTTVRIDVVVKPKFVIIPNNTIGFEGYSLKIDCTA-HG 566

Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194
            PEP + W    + ++   +   HL +G  L+IQ+    DAGRYQCIA + AG   + I 
Sbjct: 567 DPEPTITWIS--KPIMNYPEHFTHLPNG-TLIIQEVHANDAGRYQCIAGSDAGLNTTEIT 623

Query: 195 -TLKIHIKPYLITGPEDVVAQT 215
            T++    P  +  P  V+ +T
Sbjct: 624 LTVQKGTPPDQVPVPAQVMTRT 645



 Score = 57.6 bits (133), Expect = 2e-06
 Identities = 75/300 (25%), Positives = 120/300 (40%), Gaps = 46/300 (15%)

Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSC 272
           G+S+   C V  D   +V++  +    N+P+    R+ +    SL++ +V   D G+Y C
Sbjct: 6   GTSIILSCEV--DQAENVVFSWTLN--NVPVEDSSRIFMDTSNSLKIGDVSREDAGQYRC 61

Query: 273 EAENSVGAVSASGYLTVYDPPSINLS------------PN-SVNVESGNVARFTCTATGR 319
             E S  A +        DP ++N++            PN   +VE G      C A+G 
Sbjct: 62  VVEPSSTAEAPMSS----DPANVNVTWISEELRVQLNRPNLPEDVEEGGKVTLICRASGN 117

Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379
           P P + W  +  +T +  G + D         G T L I      DS     C A N AG
Sbjct: 118 PVPMVTWYHD--QTPVVAGSNVD-------ISG-TRLKIKSATPLDS-GIYSCMATNVAG 166

Query: 380 SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA-- 437
           S      +     D   P ++   P++    +    +F C     P P + WY   +A  
Sbjct: 167 SMPSTENVQFNIVDSNTP-VVEVAPTDAIRVLGDSIMFHCQFSGDPTPPVEWYTTSKAGG 225

Query: 438 ----LIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
                + N     T    +G+L L +L   D G + CV  S HG+  ++ A L  + +NP
Sbjct: 226 EIPPQLMNDTETGTYIIGNGSLSLANLTAGDEGEFQCVCDSPHGR-PFASARLTIATVNP 284



 Score = 56.4 bits (130), Expect = 4e-06
 Identities = 90/379 (23%), Positives = 138/379 (36%), Gaps = 50/379 (13%)

Query: 30  TLNCR-----AGGSPSPAIRWYKGGVLVV--SDTHRSILPAGGLFFLRATHGRVHSDAGV 82
           T+NC       GG P+P+I W K  +  V    T    +       L        SD G 
Sbjct: 300 TINCSYPAGDVGGIPTPSIHWLKPSLREVPLDGTKTKRVRVEEQKNLLVFDPIKKSDEGN 359

Query: 83  YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW 142
           Y C ++N  G   +      V     +    P      + +   L C    G+P P + W
Sbjct: 360 YTCVSSNMAG--ETTQILKVVVATAPKITTRPVDVHIREREEATLRC-NATGTPTPTISW 416

Query: 143 KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKP 202
               + +       + +   G+LVI                N+A TR +AI  LK + +P
Sbjct: 417 TFGTRDIT--NKQGIEVSADGSLVI----------------NSAMTRHNAI--LKFNPRP 456

Query: 203 YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNV 262
             +T  +      G      C       P + W +    G  P   +   + G L+ +  
Sbjct: 457 IAVTSLD-----RGEMNRLVCHATASIQPFIAWHKQGIIGTWP-DHISEPNSGVLQFNPA 510

Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEP 322
             +D G Y C A   +  ++ +  + V   P   + PN+     G   +  CTA G PEP
Sbjct: 511 EASDAGTYICIASTGLERINTTVRIDVVVKPKFVIIPNNTIGFEGYSLKIDCTAHGDPEP 570

Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
           T+ W       I  P M+  + H T + +G   L I +   ND+     C A + AG + 
Sbjct: 571 TITW-------ISKPIMNYPE-HFTHLPNG--TLIIQEVHANDA-GRYQCIAGSDAGLNT 619

Query: 383 VRGKLTV---TSDDDRPPP 398
               LTV   T  D  P P
Sbjct: 620 TEITLTVQKGTPPDQVPVP 638


>UniRef50_A0S6W8 Cluster: Hemicentin-like protein 2; n=2; Spodoptera
           frugiperda|Rep: Hemicentin-like protein 2 - Spodoptera
           frugiperda (Fall armyworm)
          Length = 881

 Score =  114 bits (275), Expect = 1e-23
 Identities = 135/497 (27%), Positives = 205/497 (41%), Gaps = 54/497 (10%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
           VT   AP I + P +V   + +  TL C+  G P P I+W   G          +   G 
Sbjct: 22  VTGIAAPKI-QMPANVKAVKGKAVTLECKVSGVPKPTIKWQFRG--KSGSKFVPLAETGS 78

Query: 66  LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK-QSAQGD- 123
           +  LR  +     D G Y C A N+   A+    T  +     +    P +  QS +GD 
Sbjct: 79  V--LRINNVEAKHD-GQYKCVAENA--LAKDEKVTTLIVQETPKIVSRPTTTYQSTEGDA 133

Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
           T+ + C+   G P+P + WK +G+ +     S  + V+ G L+I+    TD   Y+C+A 
Sbjct: 134 TLKIPCVAV-GDPKPTITWKMDGRPIAV--PSSKYAVEDGALIIKYPTVTDTKSYECVAT 190

Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVLW-RRSAGG 241
           N AG+  +   T  I  KP  + G        G  V  +C+ V G P P++ W   ++G 
Sbjct: 191 NEAGSVTTTFKTF-IRQKPQ-VAGVATKKVYLGMPVDIECKIVKGWPKPNIRWFVNNSGK 248

Query: 242 GNMPLGRVKVLDDGSLRLDNVILADE---GEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
             +P+        G+L + +++ A+    G Y C A+N  G       LTV   P I   
Sbjct: 249 QFVPIA-------GALDVMHIVKAENKHTGRYKCVAQNEAGTAEHITSLTVESRPEIVTK 301

Query: 299 PNSVNVESGNVA-RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
           P  V    G++A +  C   G P P + W ++G   +I P     KY     FD  + L 
Sbjct: 302 PKPVEAIEGDLAIKIPCDVVGVPRPVITWKLKG--AVIKP---NSKYS----FDNGS-LV 351

Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
           I   +K+D      C A NY GS      LT    + RP    T       L        
Sbjct: 352 IQKPNKSDVAK-YTCEANNYLGSVSSTTDLTF---EKRPSTFGTK--HFVYLLYGENKNI 405

Query: 418 PCTAICTPEPIIAWY-FEGE---ALIQNHRRNVTNDGTLVLKDLDK-SDSGTYTCVASSR 472
            C A  +    + W+  EGE     IQ  + +V+NDG       DK   + T+T + +  
Sbjct: 406 ECEAYRSKSQTLKWFDNEGELNKKSIQITKASVSNDGNYTCHVSDKQGHTETHTYIVN-- 463

Query: 473 HGKYVWSGALLVDSPIN 489
                    LL D+P+N
Sbjct: 464 ---VGGPPKLLADNPLN 477


>UniRef50_UPI0000F1ECB5 Cluster: PREDICTED: similar to novel
           hemicentin protein; n=1; Danio rerio|Rep: PREDICTED:
           similar to novel hemicentin protein - Danio rerio
          Length = 841

 Score =  114 bits (274), Expect = 2e-23
 Identities = 128/496 (25%), Positives = 196/496 (39%), Gaps = 72/496 (14%)

Query: 4   DYVTSGEAPYIIEQPL---DVTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVS-DTHR 58
           +Y    +AP +I       +VT+   Q   + CR  G P P++ W + G VL  + D H 
Sbjct: 367 EYTIEVQAPPVISGTSGVQEVTIMAGQEVDMQCRVSGRPLPSVEWTHDGEVLSPNGDPHV 426

Query: 59  SILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGT-ARSRNATLHVAVLREEFRLEPESK 117
             L  G +  +++   R   D G+Y C ATN+ GT  R    T+  A L  +   E    
Sbjct: 427 EFLEKGQVLRVKSVRPR---DRGLYQCVATNNAGTQTRQFRLTIQAAPLIRDSG-EDSEV 482

Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAG 176
               G   VL C    G P P + W K+ Q ++     ++    GG +L +  AR  DAG
Sbjct: 483 TVVLGFPAVLHC-EVEGIPLPTITWLKDNQPIV--SSPQLTYTQGGQSLRVAAARGEDAG 539

Query: 177 RYQCIARNAAGTRESAIATLKIHIKPY-------LITGPEDVVAQTGSSVTFQCRVGGDP 229
            Y C A N AGT      TL+I + P        L  G  +   +   ++T  C   G P
Sbjct: 540 AYTCRATNPAGTAHRHY-TLRIMVPPQIEGDSTILSFGRREEKVRINGTLTLSCLAKGFP 598

Query: 230 LPDVLWRRSAG--GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYL 287
            P   W +      GN   G    ++   L +DN +L+ EG+Y+C   NS G      +L
Sbjct: 599 EPVTQWFKDGQLLNGNTHSGLS--VNSHMLHVDNAMLSHEGQYTCVVSNSAGEDKRDFHL 656

Query: 288 TVYDPPSINL---------------------SPNSV----NVESGNVARFTCTATGRPEP 322
           T+  PP  +                      SP+ +     V  G+    +C +   P P
Sbjct: 657 TIQVPPVFHRVINGAADFTLGEREGDEEDPDSPDGMVERREVLLGHSISLSCESNAIPPP 716

Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
            + W  +G +     G+     H         +L I      D+     C AVN AG   
Sbjct: 717 RLSWYRQGRQLTSSDGVVLAPGH---------ILQIPRVQLEDA-GKYTCQAVNEAGEDK 766

Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLP-----IKSMAVFPCTAICTPEPIIAWYFEGEA 437
           +   L V       PP+I +G +++ +      + S     C     P P ++W  +G  
Sbjct: 767 MHYDLEVL-----VPPVI-SGQTDEFMQDVDTVVNSTVSLRCDVSGHPSPSVSWIKDGLP 820

Query: 438 LIQNHRRNVTNDGTLV 453
           L  + R N+  DG L+
Sbjct: 821 LYSDSRHNILEDGKLL 836



 Score =  104 bits (249), Expect = 2e-20
 Identities = 115/417 (27%), Positives = 170/417 (40%), Gaps = 38/417 (9%)

Query: 79  DAGVYWCEATNSYG-TARSRNATLHVA--VLREEFRLEPESKQSAQGDTVVLECLPPRGS 135
           DAGVY C AT++ G T+R  +  ++    ++  +         +  G  V+L C   +GS
Sbjct: 58  DAGVYICTATSAVGYTSREMHLIVNSKPRIVGADGSQVTVKMAAEVGSEVILPC-EVQGS 116

Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195
           P P V W +NGQT+     +   ++  G+L I D R  D+  Y C A N AG   S    
Sbjct: 117 PTPLVTWSRNGQTIP-PVTAWFTMLPSGSLKISDVRVVDSKLYTCSAVNPAG-NVSLTYN 174

Query: 196 LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
           L++  KP +   P  + A  G +V   C V G+P P V W  +          + V  D 
Sbjct: 175 LQVQAKPRIHPAPSTLKALIGQTVVLPCVVQGEPSPQVSWLHNG---------LPVASDR 225

Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS--INLSPNSVNV-----ESG- 307
            L++  V  +D G Y C A NS G  +    L V   P+  +    N + V     E G 
Sbjct: 226 MLKIQAVQHSDSGTYRCVARNSAGEDTIQIVLDVLGSPAPQVRWFKNGLEVHMERSEHGV 285

Query: 308 NVARFTCTATGRPEPTM---FWSVEGNRTIIFPGMSRDKYHAT-AVF--DGVTVLTINDT 361
           ++A       G    +    F  V  N        +R K   T  V+  +G  +L I   
Sbjct: 286 SLAEDGALVIGSASASHSGDFKCVATNEAGSVERKTRLKVLETPGVYLQNGKRLLKIYRV 345

Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIKSMAVFPCT 420
            ++D      C+A N AG +    K   T +   PP I  T+G    T+         C 
Sbjct: 346 -QHDHAGRFSCTAQNSAGEA----KREYTIEVQAPPVISGTSGVQEVTIMAGQEVDMQCR 400

Query: 421 AICTPEPIIAWYFEGEALIQN---HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
               P P + W  +GE L  N   H   +     L +K +   D G Y CVA++  G
Sbjct: 401 VSGRPLPSVEWTHDGEVLSPNGDPHVEFLEKGQVLRVKSVRPRDRGLYQCVATNNAG 457



 Score =  104 bits (249), Expect = 2e-20
 Identities = 94/330 (28%), Positives = 142/330 (43%), Gaps = 22/330 (6%)

Query: 157 MHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL--ITGPEDVVA 213
           ++L +G  L+ I   +   AGR+ C A+N+AG  +    T+++   P +   +G ++V  
Sbjct: 331 VYLQNGKRLLKIYRVQHDHAGRFSCTAQNSAGEAKREY-TIEVQAPPVISGTSGVQEVTI 389

Query: 214 QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG--RVKVLDDGS-LRLDNVILADEGEY 270
             G  V  QCRV G PLP V W    G    P G   V+ L+ G  LR+ +V   D G Y
Sbjct: 390 MAGQEVDMQCRVSGRPLPSVEWTHD-GEVLSPNGDPHVEFLEKGQVLRVKSVRPRDRGLY 448

Query: 271 SCEAENSVGAVSASGYLTVYDPPSINLS--PNSVNVESGNVARFTCTATGRPEPTMFWSV 328
            C A N+ G  +    LT+   P I  S   + V V  G  A   C   G P PT+ W +
Sbjct: 449 QCVATNNAGTQTRQFRLTIQAAPLIRDSGEDSEVTVVLGFPAVLHCEVEGIPLPTITW-L 507

Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG--K 386
           + N+ I+    S  +   T     + V      D         C A N AG++      +
Sbjct: 508 KDNQPIV----SSPQLTYTQGGQSLRVAAARGEDAG----AYTCRATNPAGTAHRHYTLR 559

Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN-HRRN 445
           + V    +    I++ G   + + I       C A   PEP+  W+ +G+ L  N H   
Sbjct: 560 IMVPPQIEGDSTILSFGRREEKVRINGTLTLSCLAKGFPEPVTQWFKDGQLLNGNTHSGL 619

Query: 446 VTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
             N   L + +   S  G YTCV S+  G+
Sbjct: 620 SVNSHMLHVDNAMLSHEGQYTCVVSNSAGE 649



 Score = 80.2 bits (189), Expect = 3e-13
 Identities = 52/173 (30%), Positives = 77/173 (44%), Gaps = 6/173 (3%)

Query: 163 GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI--TGPEDVV---AQTGS 217
           G+L I    + DAG Y C A +A G     +  + ++ KP ++   G +  V   A+ GS
Sbjct: 47  GSLYISSPTEEDAGVYICTATSAVGYTSREMHLI-VNSKPRIVGADGSQVTVKMAAEVGS 105

Query: 218 SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENS 277
            V   C V G P P V W R+            +L  GSL++ +V + D   Y+C A N 
Sbjct: 106 EVILPCEVQGSPTPLVTWSRNGQTIPPVTAWFTMLPSGSLKISDVRVVDSKLYTCSAVNP 165

Query: 278 VGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
            G VS +  L V   P I+ +P+++    G      C   G P P + W   G
Sbjct: 166 AGNVSLTYNLQVQAKPRIHPAPSTLKALIGQTVVLPCVVQGEPSPQVSWLHNG 218



 Score = 78.2 bits (184), Expect = 1e-12
 Identities = 84/292 (28%), Positives = 125/292 (42%), Gaps = 49/292 (16%)

Query: 31  LNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
           L C   GSP+P + W + G  +   T   ++LP+G L   + +  RV  D+ +Y C A N
Sbjct: 109 LPCEVQGSPTPLVTWSRNGQTIPPVTAWFTMLPSGSL---KISDVRV-VDSKLYTCSAVN 164

Query: 90  SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
             G   S    L V   +      P + ++  G TVVL C+  +G P P V W  NG  +
Sbjct: 165 PAGNV-SLTYNLQVQA-KPRIHPAPSTLKALIGQTVVLPCVV-QGEPSPQVSWLHNGLPV 221

Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
             D   RM       L IQ  + +D+G Y+C+ARN+AG  E  I                
Sbjct: 222 ASD---RM-------LKIQAVQHSDSGTYRCVARNSAG--EDTI---------------- 253

Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGE 269
            +V     S   Q R   + L +V   RS  G       V + +DG+L + +   +  G+
Sbjct: 254 QIVLDVLGSPAPQVRWFKNGL-EVHMERSEHG-------VSLAEDGALVIGSASASHSGD 305

Query: 270 YSCEAENSVGAVSASGYLTVYDPPSINLSPNS-----VNVESGNVARFTCTA 316
           + C A N  G+V     L V + P + L           V+  +  RF+CTA
Sbjct: 306 FKCVATNEAGSVERKTRLKVLETPGVYLQNGKRLLKIYRVQHDHAGRFSCTA 357



 Score = 70.5 bits (165), Expect = 3e-10
 Identities = 77/259 (29%), Positives = 106/259 (40%), Gaps = 27/259 (10%)

Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-NLSPNS 301
           N P+       DGSL + +    D G Y C A ++VG  S   +L V   P I     + 
Sbjct: 35  NRPVSAPFEAADGSLYISSPTEEDAGVYICTATSAVGYTSREMHLIVNSKPRIVGADGSQ 94

Query: 302 VNV----ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
           V V    E G+     C   G P P + WS  G +TI  P ++      T +  G   L 
Sbjct: 95  VTVKMAAEVGSEVILPCEVQGSPTPLVTWSRNG-QTI--PPVTA---WFTMLPSG--SLK 146

Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
           I+D    DS+    CSAVN AG+  +   L V     +  P I   PS     I    V 
Sbjct: 147 ISDVRVVDSK-LYTCSAVNPAGNVSLTYNLQV-----QAKPRIHPAPSTLKALIGQTVVL 200

Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
           PC     P P ++W   G          V +D  L ++ +  SDSGTY CVA +  G+  
Sbjct: 201 PCVVQGEPSPQVSWLHNG--------LPVASDRMLKIQAVQHSDSGTYRCVARNSAGEDT 252

Query: 478 WSGALLVDSPINPNIHFFR 496
               L V     P + +F+
Sbjct: 253 IQIVLDVLGSPAPQVRWFK 271



 Score = 36.3 bits (80), Expect = 5.1
 Identities = 26/81 (32%), Positives = 33/81 (40%), Gaps = 12/81 (14%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P I   P  +     Q   L C   G PSP + W   G+ V SD          +  ++A
Sbjct: 181 PRIHPAPSTLKALIGQTVVLPCVVQGEPSPQVSWLHNGLPVASDR---------MLKIQA 231

Query: 72  THGRVHSDAGVYWCEATNSYG 92
                HSD+G Y C A NS G
Sbjct: 232 VQ---HSDSGTYRCVARNSAG 249


>UniRef50_A7RGL8 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 578

 Score =  113 bits (273), Expect = 2e-23
 Identities = 93/327 (28%), Positives = 138/327 (42%), Gaps = 21/327 (6%)

Query: 22  TVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAG 81
           TV +    TL CR  G P P I W++    V +D        G +  L     ++ SDAG
Sbjct: 188 TVGKCDKYTLVCRVSGKPKPTITWFRDNTPVHTDNRVVASYEGSVSALELKEMKL-SDAG 246

Query: 82  VYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
           +Y C ATNS G T+ S   T+        F +  +  +  +   + L+ +   G P P V
Sbjct: 247 LYKCTATNSQGSTSSSAEVTIKRKDAIPTFVVGLKETEGLESSDMRLD-VKIGGFPRPTV 305

Query: 141 YWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAG--TRESAIATL 196
            + K+   L+ D +    L DG   +L+I + R  DAG Y+C+  N  G  T E+ I   
Sbjct: 306 EFYKD-YDLIVDSERHKILEDGDRCSLIITNLRPEDAGTYKCVITNLLGVETSEAVIRVQ 364

Query: 197 ------KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA----GGGNMPL 246
                 +  +KP  +   EDV A     V F+  + G P P V W R       GG   +
Sbjct: 365 EREHAPRFDVKPEFLRKVEDVTALETEQVWFEIPIQGYPRPIVEWYRGTTRIKDGGRFTI 424

Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLSPNSVN 303
              +  D  SL +D     D G Y C A N  G  +A   L V +    P  +     + 
Sbjct: 425 SESEENDMYSLVIDEARTEDSGPYKCVASNDAGKTTALLNLDVNEKVVQPEFDKEVKPIE 484

Query: 304 VESGNVARFTCTATGRPEPTMFWSVEG 330
           V+ G  A  +    G+P+P + W  +G
Sbjct: 485 VKHGEEATTSLEIKGKPKPKVTWYKDG 511



 Score = 91.9 bits (218), Expect = 1e-16
 Identities = 80/276 (28%), Positives = 119/276 (43%), Gaps = 22/276 (7%)

Query: 31  LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
           L+ + GG P P + +YK   L+V      IL  G    L  T+ R   DAG Y C  TN 
Sbjct: 293 LDVKIGGFPRPTVEFYKDYDLIVDSERHKILEDGDRCSLIITNLRPE-DAGTYKCVITNL 351

Query: 91  YGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVVLEC------LPPRGSPEPNVYW 142
            G   S  A + V        F ++PE  +  + D   LE       +P +G P P V W
Sbjct: 352 LGVETSE-AVIRVQEREHAPRFDVKPEFLRKVE-DVTALETEQVWFEIPIQGYPRPIVEW 409

Query: 143 KKNGQTLLFDGD----SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
            + G T + DG     S     D  +LVI +AR  D+G Y+C+A N AG + +A+  L +
Sbjct: 410 YR-GTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDAG-KTTALLNLDV 467

Query: 199 H---IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG--GGNMPLGRVKVLD 253
           +   ++P      + +  + G   T    + G P P V W +       +  +    + D
Sbjct: 468 NEKVVQPEFDKEVKPIEVKHGEEATTSLEIKGKPKPKVTWYKDGKVLRESKNIQLKSIGD 527

Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
             S+R+      D G Y CEA N  G  S    +T+
Sbjct: 528 TYSIRIVRTAPEDVGTYMCEATNKAGLASRKFDITI 563



 Score = 73.3 bits (172), Expect = 4e-11
 Identities = 53/198 (26%), Positives = 86/198 (43%), Gaps = 6/198 (3%)

Query: 8   SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
           +G+AP +  Q + V V       L C+   +P P + WYKG  LV  D  R      G F
Sbjct: 11  AGDAPSLSSQLMPVEVTEGNDIDLVCKVSVNPKPTVTWYKGDALVKLD-DRISAHFDGRF 69

Query: 68  FLRATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVV 126
              +       D G+Y C+  N  G A S+   T+    ++ +   E +  +  +   V 
Sbjct: 70  SRLSIQKATKDDEGIYICDVQNELGKAFSKVELTVRKRNVKPQIVGEIKDAEEVERGEVR 129

Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGD--SRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
            E +   G P+P V W + G   L DG   S     D  +L ++D ++ D+G Y+ +A+N
Sbjct: 130 FE-VRVTGFPKPRVEWYR-GPVHLTDGGRFSISEKEDMYSLTVRDLKRDDSGTYKLVAQN 187

Query: 185 AAGTRESAIATLKIHIKP 202
             G  +      ++  KP
Sbjct: 188 TVGKCDKYTLVCRVSGKP 205



 Score = 69.7 bits (163), Expect = 4e-10
 Identities = 87/364 (23%), Positives = 149/364 (40%), Gaps = 48/364 (13%)

Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRY 178
           +G+ + L C     +P+P V W K    +  D     H  DG    L IQ A + D G Y
Sbjct: 28  EGNDIDLVC-KVSVNPKPTVTWYKGDALVKLDDRISAHF-DGRFSRLSIQKATKDDEGIY 85

Query: 179 QCIARNAAGTRESAI--ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
            C  +N  G   S +     K ++KP ++   +D        V F+ RV G P P V W 
Sbjct: 86  ICDVQNELGKAFSKVELTVRKRNVKPQIVGEIKDAEEVERGEVRFEVRVTGFPKPRVEWY 145

Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
           R         G V + D G   +       E  YS    +     S +  L         
Sbjct: 146 R---------GPVHLTDGGRFSISE----KEDMYSLTVRDLKRDDSGTYKL--------- 183

Query: 297 LSPNSVNVESGNVARFT--CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG-V 353
           ++ N+V    G   ++T  C  +G+P+PT+ W  +       P  + ++    A ++G V
Sbjct: 184 VAQNTV----GKCDKYTLVCRVSGKPKPTITWFRDNT-----PVHTDNR--VVASYEGSV 232

Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413
           + L + +   +D+     C+A N  GS+    ++T+   D   P  +      + L    
Sbjct: 233 SALELKEMKLSDA-GLYKCTATNSQGSTSSSAEVTIKRKD-AIPTFVVGLKETEGLESSD 290

Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVAS 470
           M +        P P + +Y + + ++ + R  +  DG   +L++ +L   D+GTY CV +
Sbjct: 291 MRL-DVKIGGFPRPTVEFYKDYDLIVDSERHKILEDGDRCSLIITNLRPEDAGTYKCVIT 349

Query: 471 SRHG 474
           +  G
Sbjct: 350 NLLG 353



 Score = 60.1 bits (139), Expect = 4e-07
 Identities = 46/180 (25%), Positives = 75/180 (41%), Gaps = 6/180 (3%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA--GGLFFL 69
           P  + +  DVT    +         G P P + WY+G   +      +I  +    ++ L
Sbjct: 376 PEFLRKVEDVTALETEQVWFEIPIQGYPRPIVEWYRGTTRIKDGGRFTISESEENDMYSL 435

Query: 70  RATHGRVHSDAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
                R   D+G Y C A+N  G T    N  ++  V++ EF  E +  +   G+     
Sbjct: 436 VIDEART-EDSGPYKCVASNDAGKTTALLNLDVNEKVVQPEFDKEVKPIEVKHGEEATTS 494

Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAG 187
            L  +G P+P V W K+G+ L    + ++  + D  ++ I      D G Y C A N AG
Sbjct: 495 -LEIKGKPKPKVTWYKDGKVLRESKNIQLKSIGDTYSIRIVRTAPEDVGTYMCEATNKAG 553



 Score = 56.0 bits (129), Expect = 6e-06
 Identities = 55/212 (25%), Positives = 89/212 (41%), Gaps = 17/212 (8%)

Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
           D PS++     V V  GN     C  +  P+PT+ W  +G+  +            +A F
Sbjct: 13  DAPSLSSQLMPVEVTEGNDIDLVCKVSVNPKPTVTW-YKGDALVKLDD------RISAHF 65

Query: 351 DG-VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409
           DG  + L+I    K+D     +C   N  G +F + +LTV   + +P  +   G      
Sbjct: 66  DGRFSRLSIQKATKDDE-GIYICDVQNELGKAFSKVELTVRKRNVKPQIV---GEIKDAE 121

Query: 410 PIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTY 465
            ++   V F       P+P + WY     L    R +++      +L ++DL + DSGTY
Sbjct: 122 EVERGEVRFEVRVTGFPKPRVEWYRGPVHLTDGGRFSISEKEDMYSLTVRDLKRDDSGTY 181

Query: 466 TCVASSRHGKY-VWSGALLVDSPINPNIHFFR 496
             VA +  GK   ++    V     P I +FR
Sbjct: 182 KLVAQNTVGKCDKYTLVCRVSGKPKPTITWFR 213



 Score = 46.0 bits (104), Expect = 0.006
 Identities = 28/98 (28%), Positives = 41/98 (41%), Gaps = 2/98 (2%)

Query: 21  VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
           + V   + AT +    G P P + WYK G ++    +  +   G  + +R        D 
Sbjct: 483 IEVKHGEEATTSLEIKGKPKPKVTWYKDGKVLRESKNIQLKSIGDTYSIRIVR-TAPEDV 541

Query: 81  GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ 118
           G Y CEATN  G A SR   + +       +L  ES Q
Sbjct: 542 GTYMCEATNKAGLA-SRKFDITIKGRFRCIKLHRESSQ 578


>UniRef50_A7RGM0 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 621

 Score =  113 bits (271), Expect = 4e-23
 Identities = 119/462 (25%), Positives = 188/462 (40%), Gaps = 55/462 (11%)

Query: 30  TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
           +L+    G P+P + W+K    V       +        L+   G+   D+G Y   A +
Sbjct: 183 SLDLTVTGKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHSLKIKGGKP-DDSGKYTVVAES 241

Query: 90  SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
             G   +R   +++   + EF+ + +  Q  +GD  V E                 G+ L
Sbjct: 242 PAGRD-TRTYEVNIKGEKPEFKQKMQPLQVLEGDEKVAE----------------EGRFL 284

Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT--- 206
           + D +      D  +L+I +A+  D+G Y C A N  G    A A  +I I+  L+    
Sbjct: 285 IVDDEEG----DLFSLIIGNAKPLDSGVYICQATNDTG---KATAEAEIQIEELLVAPEF 337

Query: 207 GPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLD 260
             E+    T      +T +  V G P P+V W +     N PL    R+ +   G   + 
Sbjct: 338 AEEEATQLTLIEDDDMTLELHVTGKPKPEVHWTKD----NKPLTEDDRIIIDHKGDSCIV 393

Query: 261 NVILA---DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
           +++     D G Y CEA+N  G  + +  + V + P I  S   +    GN    TC  T
Sbjct: 394 DIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNVEEAPEITESLQEMEELEGNPVTLTCKFT 453

Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
           G P P   W          P    D+Y      D  T L I  T ++D  +T  C A N 
Sbjct: 454 GTPAPVAEWFKAST-----PLTDTDRYEFIEEGDSYT-LIIKTTVRDDD-DTYKCVASNQ 506

Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEPIIAWYFEG 435
            G    RG L VT  +   PP IT     + + +  K   V   T +  P P + W+ +G
Sbjct: 507 VGKVTCRGDLKVT--EKMFPPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKDG 564

Query: 436 EALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHG 474
           + + Q+ R N+   G   TL +   +  D+G+YTC A ++ G
Sbjct: 565 KPIRQSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMG 606



 Score = 88.6 bits (210), Expect = 9e-16
 Identities = 118/494 (23%), Positives = 188/494 (38%), Gaps = 53/494 (10%)

Query: 11  APYIIEQPL--DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
           AP II+ PL  ++ V       L C   G P   + WYK   L+  D  R +    G   
Sbjct: 70  APIIIK-PLNDEIDVLEGDSVRLECVISGGPDAQVLWYKDDYLLEED-ERIMYDTDGDQH 127

Query: 69  LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTVV 126
                     D   Y C  TN  G+   +       ++  EF+ EPE        GD V 
Sbjct: 128 TLIIQSAELDDEAEYKCVVTNIAGSVDVKTEL----IIAPEFQKEPEKSTFDVNTGDDVS 183

Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV---DGGNLVIQDARQTDAGRYQCIAR 183
           L+ L   G P P V W K+ + +   G  R+ +    D  +L I+  +  D+G+Y  +A 
Sbjct: 184 LD-LTVTGKPTPKVEWFKDDKPV--KGTRRLEVKAKDDEHSLKIKGGKPDDSGKYTVVAE 240

Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
           + AG R++   T +++IK     G +    Q    +     + GD        + A  G 
Sbjct: 241 SPAG-RDTR--TYEVNIK-----GEKPEFKQKMQPLQV---LEGD-------EKVAEEGR 282

Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD----PPSINLSP 299
             +   +  D  SL + N    D G Y C+A N  G  +A   + + +    P       
Sbjct: 283 FLIVDDEEGDLFSLIIGNAKPLDSGVYICQATNDTGKATAEAEIQIEELLVAPEFAEEEA 342

Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
             + +   +        TG+P+P + W+ +         +  D    + + D +  +T N
Sbjct: 343 TQLTLIEDDDMTLELHVTGKPKPEVHWTKDNKPLTEDDRIIIDHKGDSCIVD-IMAVTPN 401

Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419
           D+       T  C A N AG   V  +  + + ++ P   IT           +     C
Sbjct: 402 DS------GTYKCEAKNKAG---VNTRTFIVNVEEAPE--ITESLQEMEELEGNPVTLTC 450

Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGKY 476
               TP P+  W+     L    R     +G   TL++K   + D  TY CVAS++ GK 
Sbjct: 451 KFTGTPAPVAEWFKASTPLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTYKCVASNQVGKV 510

Query: 477 VWSGALLVDSPINP 490
              G L V   + P
Sbjct: 511 TCRGDLKVTEKMFP 524



 Score = 79.0 bits (186), Expect = 7e-13
 Identities = 74/279 (26%), Positives = 115/279 (41%), Gaps = 17/279 (6%)

Query: 16  EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75
           E+   +T+      TL     G P P + W K    +  D  R I+   G   +      
Sbjct: 340 EEATQLTLIEDDDMTLELHVTGKPKPEVHWTKDNKPLTEDD-RIIIDHKGDSCIVDIMAV 398

Query: 76  VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGS 135
             +D+G Y CEA N  G   +R   ++V     E     +  +  +G+ V L C    G+
Sbjct: 399 TPNDSGTYKCEAKNKAGV-NTRTFIVNVEEA-PEITESLQEMEELEGNPVTLTC-KFTGT 455

Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAI 193
           P P   W K   T L D D    + +G +  L+I+   + D   Y+C+A N  G + +  
Sbjct: 456 PAPVAEWFK-ASTPLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTYKCVASNQVG-KVTCR 513

Query: 194 ATLKIHIK--PYLITGPE---DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
             LK+  K  P  IT PE    +V      +     + G+P PDV W +  G       R
Sbjct: 514 GDLKVTEKMFPPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKD-GKPIRQSSR 572

Query: 249 VKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSAS 284
           + +   G   +L +      D G Y+CEA+N +G  S +
Sbjct: 573 LNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSSTT 611



 Score = 77.0 bits (181), Expect = 3e-12
 Identities = 74/251 (29%), Positives = 105/251 (41%), Gaps = 18/251 (7%)

Query: 37  GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG-TAR 95
           G P P I+W+K    V       +     +  L    G    D   Y C+ATN  G T R
Sbjct: 4   GEPKPEIQWFKDDKPVKPSQKIRVDYRDDIHSLTIV-GASPDDTAKYTCKATNKSGTTTR 62

Query: 96  SRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155
           + N  +   ++ +    E +     +GD+V LEC+   G P+  V W K+   LL + + 
Sbjct: 63  NINVDISAPIIIKPLNDEID---VLEGDSVRLECV-ISGGPDAQVLWYKD-DYLLEEDER 117

Query: 156 RMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVV- 212
            M+  DG    L+IQ A   D   Y+C+  N AG   S     ++ I P     PE    
Sbjct: 118 IMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAG---SVDVKTELIIAPEFQKEPEKSTF 174

Query: 213 -AQTGSSVTFQCRVGGDPLPDVLWRR--SAGGGNMPLGRVKVLDD-GSLRLDNVILADEG 268
              TG  V+    V G P P V W +      G   L  VK  DD  SL++      D G
Sbjct: 175 DVNTGDDVSLDLTVTGKPTPKVEWFKDDKPVKGTRRL-EVKAKDDEHSLKIKGGKPDDSG 233

Query: 269 EYSCEAENSVG 279
           +Y+  AE+  G
Sbjct: 234 KYTVVAESPAG 244



 Score = 65.3 bits (152), Expect = 1e-08
 Identities = 51/199 (25%), Positives = 82/199 (41%), Gaps = 10/199 (5%)

Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESA 192
           G P+P + W K+ + +      R+   D   +L I  A   D  +Y C A N +GT    
Sbjct: 4   GEPKPEIQWFKDDKPVKPSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGT---T 60

Query: 193 IATLKIHIKPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250
              + + I   +I  P  +++    G SV  +C + G P   VLW +          R+ 
Sbjct: 61  TRNINVDISAPIIIKPLNDEIDVLEGDSVRLECVISGGPDAQVLWYKDDYLLEED-ERIM 119

Query: 251 VLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESG 307
              DG   +L + +  L DE EY C   N  G+V     L +          ++ +V +G
Sbjct: 120 YDTDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIIAPEFQKEPEKSTFDVNTG 179

Query: 308 NVARFTCTATGRPEPTMFW 326
           +      T TG+P P + W
Sbjct: 180 DDVSLDLTVTGKPTPKVEW 198



 Score = 64.1 bits (149), Expect = 2e-08
 Identities = 51/190 (26%), Positives = 79/190 (41%), Gaps = 10/190 (5%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
           EAP I E   ++      P TL C+  G+P+P   W+K     ++DT R      G  + 
Sbjct: 427 EAPEITESLQEMEELEGNPVTLTCKFTGTPAPVAEWFKAST-PLTDTDRYEFIEEGDSYT 485

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS---AQGDTVV 126
                 V  D   Y C A+N  G    R        +       PE  +     + + +V
Sbjct: 486 LIIKTTVRDDDDTYKCVASNQVGKVTCRGDLKVTEKMFPPEITRPERTEKIVLLEKEELV 545

Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIAR 183
           +  +   G+P P+V W K+G+ +     SR+++   G+   L I      DAG Y C A+
Sbjct: 546 IN-VTILGNPRPDVKWFKDGKPI--RQSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQ 602

Query: 184 NAAGTRESAI 193
           N  GT  + I
Sbjct: 603 NKMGTSSTTI 612



 Score = 52.8 bits (121), Expect = 5e-05
 Identities = 57/258 (22%), Positives = 101/258 (39%), Gaps = 19/258 (7%)

Query: 224 RVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDD-GSLRLDNVILADEGEYSCEAENSVGA 280
           ++ G+P P++ W +       P  +++V   DD  SL +      D  +Y+C+A N  G 
Sbjct: 1   KITGEPKPEIQWFKDDKPVK-PSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGT 59

Query: 281 VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340
            + +  + +  P  I    + ++V  G+  R  C  +G P+  + W  +     +     
Sbjct: 60  TTRNINVDISAPIIIKPLNDEIDVLEGDSVRLECVISGGPDAQVLWYKDD---YLLEEDE 116

Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII 400
           R  Y      DG     I  + + D      C   N AGS  V+ +L +  +  + P   
Sbjct: 117 RIMYDT----DGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIIAPEFQKEPE-- 170

Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDL 457
               S   +          T    P P + W+ + + +    R  V    ++ +L +K  
Sbjct: 171 ---KSTFDVNTGDDVSLDLTVTGKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHSLKIKGG 227

Query: 458 DKSDSGTYTCVASSRHGK 475
              DSG YT VA S  G+
Sbjct: 228 KPDDSGKYTVVAESPAGR 245


>UniRef50_UPI0000E46E64 Cluster: PREDICTED: similar to SAPS287; n=1;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           SAPS287 - Strongylocentrotus purpuratus
          Length = 1243

 Score =  112 bits (269), Expect = 6e-23
 Identities = 86/297 (28%), Positives = 130/297 (43%), Gaps = 26/297 (8%)

Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSP-EPNVYWKKNGQTLLFDGD----SRMHLVDGGN 164
           F ++PE+  S + D V L C     S  +  + WKK+ + ++ D +     R++   G N
Sbjct: 474 FSVDPETVTSLKNDNVSLICTAGSTSDVQVTMLWKKD-KAIMEDANPIYFERLN-PSGVN 531

Query: 165 -----LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSV 219
                L +   ++ D GR+QCI  N  G   S  A + +HI P     P  V  + G   
Sbjct: 532 EYTSVLNLPHIKEADQGRFQCIISNEFGVTYSKKARVTVHIYPSFTVTPRHVSVRVGGIA 591

Query: 220 TFQCRVGGDPLPDVLWRRSAGGGNMPLGR---VKVLDD-GSLRLDNVILADEGEYSCEAE 275
              C   G P P + W++  GG N P  R   +KV  +     +DNV ++D G Y+C A 
Sbjct: 592 ELPCAATGHPTPKIAWQKD-GGINFPAARQRRIKVKTELAEFYIDNVQISDTGVYTCTAL 650

Query: 276 NSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII 335
           N+ G +S +  LTV +PP        + VE G  A   C   G P P++ W  +     +
Sbjct: 651 NAAGTISTNATLTVLEPPLFTRQMKDLTVEVGEPAVLECNVEGSPRPSIRWFKDEEPFTL 710

Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD 392
             GM     H T  FD   ++ +N   ++    T  C A N  G      KL VT +
Sbjct: 711 SDGM-----HLTD-FDRYLII-MNAAGRDG--GTYTCEATNSLGVRTDTAKLVVTQN 758



 Score = 94.7 bits (225), Expect = 1e-17
 Identities = 65/230 (28%), Positives = 105/230 (45%), Gaps = 13/230 (5%)

Query: 257 LRLDNVILADEGEYSCEAENSVGAV-SASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315
           L L ++  AD+G + C   N  G   S    +TV+  PS  ++P  V+V  G +A   C 
Sbjct: 537 LNLPHIKEADQGRFQCIISNEFGVTYSKKARVTVHIYPSFTVTPRHVSVRVGGIAELPCA 596

Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
           ATG P P + W  +G   I FP   + +     V   +    I++   +D+     C+A+
Sbjct: 597 ATGHPTPKIAWQKDGG--INFPAARQRRIK---VKTELAEFYIDNVQISDT-GVYTCTAL 650

Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG 435
           N AG+      LTV       PP+ T    + T+ +   AV  C    +P P I W+ + 
Sbjct: 651 NAAGTISTNATLTVLE-----PPLFTRQMKDLTVEVGEPAVLECNVEGSPRPSIRWFKDE 705

Query: 436 EALIQNHRRNVTN-DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
           E    +   ++T+ D  L++ +    D GTYTC A++  G    +  L+V
Sbjct: 706 EPFTLSDGMHLTDFDRYLIIMNAAGRDGGTYTCEATNSLGVRTDTAKLVV 755



 Score = 77.0 bits (181), Expect = 3e-12
 Identities = 65/181 (35%), Positives = 84/181 (46%), Gaps = 10/181 (5%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFFLR 70
           P     P  V+V     A L C A G P+P I W K GG+   +   R I     L    
Sbjct: 574 PSFTVTPRHVSVRVGGIAELPCAATGHPTPKIAWQKDGGINFPAARQRRIKVKTELAEFY 633

Query: 71  ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
             + ++ SD GVY C A N+ GT  S NATL V +    F  + +      G+  VLEC 
Sbjct: 634 IDNVQI-SDTGVYTCTALNAAGTI-STNATLTV-LEPPLFTRQMKDLTVEVGEPAVLEC- 689

Query: 131 PPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGT 188
              GSP P++ W K+ +   L DG   MHL D    L+I +A   D G Y C A N+ G 
Sbjct: 690 NVEGSPRPSIRWFKDEEPFTLSDG---MHLTDFDRYLIIMNAAGRDGGTYTCEATNSLGV 746

Query: 189 R 189
           R
Sbjct: 747 R 747



 Score = 53.6 bits (123), Expect = 3e-05
 Identities = 34/94 (36%), Positives = 41/94 (43%), Gaps = 4/94 (4%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
           E P    Q  D+TV   +PA L C   GSP P+IRW+K            +        +
Sbjct: 666 EPPLFTRQMKDLTVEVGEPAVLECNVEGSPRPSIRWFKDEEPFTLSDGMHLTDFDRYLII 725

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103
               GR   D G Y CEATNS G  R+  A L V
Sbjct: 726 MNAAGR---DGGTYTCEATNSLG-VRTDTAKLVV 755



 Score = 41.1 bits (92), Expect = 0.18
 Identities = 46/198 (23%), Positives = 78/198 (39%), Gaps = 11/198 (5%)

Query: 296 NLSPNSVNVESGNVARFTCTA--TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
           ++ P +V     +     CTA  T   + TM W  +         +  ++ + + V +  
Sbjct: 475 SVDPETVTSLKNDNVSLICTAGSTSDVQVTMLWKKDKAIMEDANPIYFERLNPSGVNEYT 534

Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413
           +VL +    + D +    C   N  G ++ + K  VT       P  T  P + ++ +  
Sbjct: 535 SVLNLPHIKEAD-QGRFQCIISNEFGVTYSK-KARVTV---HIYPSFTVTPRHVSVRVGG 589

Query: 414 MAVFPCTAICTPEPIIAWYFEG----EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
           +A  PC A   P P IAW  +G     A  Q   +  T      + ++  SD+G YTC A
Sbjct: 590 IAELPCAATGHPTPKIAWQKDGGINFPAARQRRIKVKTELAEFYIDNVQISDTGVYTCTA 649

Query: 470 SSRHGKYVWSGALLVDSP 487
            +  G    +  L V  P
Sbjct: 650 LNAAGTISTNATLTVLEP 667


>UniRef50_UPI0000DB72ED Cluster: PREDICTED: similar to CG33950-PD,
            isoform D; n=1; Apis mellifera|Rep: PREDICTED: similar to
            CG33950-PD, isoform D - Apis mellifera
          Length = 3382

 Score =  112 bits (269), Expect = 6e-23
 Identities = 96/326 (29%), Positives = 141/326 (43%), Gaps = 23/326 (7%)

Query: 79   DAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVVLECLPPRGSP 136
            D+G+Y C   N  GT   +   + V   +     ++ PE +   QG    ++C    G P
Sbjct: 1869 DSGIYKCTTINYIGTVAQKTINITVTPRKPLPTVKVTPEKQTVPQGSIAEVKCFTT-GEP 1927

Query: 137  EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE-SAIAT 195
               V W K  + +       +  + G  L I + +  D G Y C    ++G+ E SAI  
Sbjct: 1928 GVQVKWSKYLEQM----SPNVQQI-GDTLRIVNIQIADRGVYVCRVTGSSGSHEASAIIE 1982

Query: 196  LKIHIKPYLITGPEDVVAQT-GSSVTFQCR-VGGDPLPDVLWRRSAGGGNMPLGRVKVLD 253
            ++    P +   P++V     G S   QCR + G P+P + W  S   G      +K L 
Sbjct: 1983 VEPREPPLVEIYPKNVPPVILGGSTDLQCRAIAGIPIPVLQW--SHEDGRPFASNIKHLP 2040

Query: 254  DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS--VNVESGNVAR 311
             G LRL N+   D G Y C A NSVG+ SA+ Y+ V   P I ++P S  + V+ G+  R
Sbjct: 2041 GGVLRLSNITTNDGGSYVCSAVNSVGSNSATVYIEVQSVPIILITPKSGILTVKPGDRVR 2100

Query: 312  FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371
              C+ATG P+PT+ WS   N   I P  + +            V  I     ND   +  
Sbjct: 2101 LVCSATGYPQPTVAWSKHMN---IVPLTTNEVIDTPQ----KAVYEIYSASPND-EGSYT 2152

Query: 372  CSAVNYAGSSFVRGKLTVTSDDDRPP 397
            C A N AG    R  + V   +  PP
Sbjct: 2153 CHANNAAGIVEERVYIRVEDSEVYPP 2178



 Score =  111 bits (267), Expect = 1e-22
 Identities = 130/482 (26%), Positives = 191/482 (39%), Gaps = 53/482 (10%)

Query: 11   APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
            AP  I  P  + V     A   C A G+P P I W    + V    +  ++   G + L+
Sbjct: 1714 APRTIVIPPSLQVVEGHSAEFRCEASGNPPPQIEW----IRVHGPMNPEVIVYNGAWILK 1769

Query: 71   ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-------EFRLEPESKQSAQGD 123
            A      SDA  Y C A N+ G    R   L+V    E          + P     + GD
Sbjct: 1770 AVS---KSDAAEYKCIARNNIG-VDERTVILYVKDNFETPPSHSIPPTITPPQWIGSVGD 1825

Query: 124  TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
            T+V+ C+P   S + NV W +     L    ++      G L I +    D+G Y+C   
Sbjct: 1826 TIVITCIP---SLDANVTWTRERNIPLPPTANQR----DGILTIVNPSTYDSGIYKCTTI 1878

Query: 184  NAAGTRESAIATLKIHIK---PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
            N  GT       + +  +   P +   PE      GS    +C   G+P   V W +   
Sbjct: 1879 NYIGTVAQKTINITVTPRKPLPTVKVTPEKQTVPQGSIAEVKCFTTGEPGVQVKWSKYL- 1937

Query: 241  GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV--YDPPSINLS 298
                    V+ + D +LR+ N+ +AD G Y C    S G+  AS  + V   +PP + + 
Sbjct: 1938 --EQMSPNVQQIGD-TLRIVNIQIADRGVYVCRVTGSSGSHEASAIIEVEPREPPLVEIY 1994

Query: 299  PNSV-NVESGNVARFTCTA-TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
            P +V  V  G      C A  G P P + WS E  R    P  S  K+       G  VL
Sbjct: 1995 PKNVPPVILGGSTDLQCRAIAGIPIPVLQWSHEDGR----PFASNIKH-----LPG-GVL 2044

Query: 357  TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK--SM 414
             +++   ND   + VCSAVN  GS+     + V S      PII   P +  L +K    
Sbjct: 2045 RLSNITTNDG-GSYVCSAVNSVGSNSATVYIEVQS-----VPIILITPKSGILTVKPGDR 2098

Query: 415  AVFPCTAICTPEPIIAW--YFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
                C+A   P+P +AW  +     L  N   +        +     +D G+YTC A++ 
Sbjct: 2099 VRLVCSATGYPQPTVAWSKHMNIVPLTTNEVIDTPQKAVYEIYSASPNDEGSYTCHANNA 2158

Query: 473  HG 474
             G
Sbjct: 2159 AG 2160



 Score = 93.1 bits (221), Expect = 4e-17
 Identities = 119/513 (23%), Positives = 201/513 (39%), Gaps = 63/513 (12%)

Query: 43   IRWYK-GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATL 101
            I+W K GG L      RS+    GL  +R    +V SD+G+Y C+ ++       +N TL
Sbjct: 1647 IKWEKEGGQLPPG---RSVDDNHGLLVIRDV--KV-SDSGIYVCQVSDGVHIGY-KNVTL 1699

Query: 102  HVAVLREEFR---------LEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFD 152
             V    +            + P S Q  +G +    C    G+P P + W +    +   
Sbjct: 1700 TVGAFPQSLLDIPTAPRTIVIPPSLQVVEGHSAEFRC-EASGNPPPQIEWIRVHGPM--- 1755

Query: 153  GDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI--------ATLKIHIKPYL 204
              +   +V  G  +++   ++DA  Y+CIARN  G  E  +         T   H  P  
Sbjct: 1756 --NPEVIVYNGAWILKAVSKSDAAEYKCIARNNIGVDERTVILYVKDNFETPPSHSIPPT 1813

Query: 205  ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
            IT P+  +   G ++   C    D   +V W R     N+PL       DG L + N   
Sbjct: 1814 ITPPQ-WIGSVGDTIVITCIPSLD--ANVTWTRER---NIPLPPTANQRDGILTIVNPST 1867

Query: 265  ADEGEYSCEAENSVGAVSASGYLTVYDP----PSINLSPNSVNVESGNVARFTCTATGRP 320
             D G Y C   N +G V+         P    P++ ++P    V  G++A   C  TG P
Sbjct: 1868 YDSGIYKCTTINYIGTVAQKTINITVTPRKPLPTVKVTPEKQTVPQGSIAEVKCFTTGEP 1927

Query: 321  EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGS 380
               + WS           + +   +   + D + ++ I   D    R   VC     +GS
Sbjct: 1928 GVQVKWS---------KYLEQMSPNVQQIGDTLRIVNIQIAD----RGVYVCRVTGSSGS 1974

Query: 381  SFVRGKLTVTSDDDRPPPIITNGPSN-QTLPIKSMAVFPCTAIC-TPEPIIAWYFEGEAL 438
                  + V   + R PP++   P N   + +       C AI   P P++ W  E    
Sbjct: 1975 HEASAIIEV---EPREPPLVEIYPKNVPPVILGGSTDLQCRAIAGIPIPVLQWSHEDGRP 2031

Query: 439  IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAA 498
              ++ +++   G L L ++  +D G+Y C A +  G    S  + ++    P I     +
Sbjct: 2032 FASNIKHLPG-GVLRLSNITTNDGGSYVCSAVNSVGSN--SATVYIEVQSVPIILITPKS 2088

Query: 499  DVSSL-PGPPTKPITHNVTDTSVTLSWSQNNKI 530
             + ++ PG   + +         T++WS++  I
Sbjct: 2089 GILTVKPGDRVRLVCSATGYPQPTVAWSKHMNI 2121



 Score = 68.5 bits (160), Expect = 1e-09
 Identities = 88/325 (27%), Positives = 126/325 (38%), Gaps = 39/325 (12%)

Query: 31   LNCRA-GGSPSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
            L CRA  G P P ++W ++ G    S+     LP G L     T     +D G Y C A 
Sbjct: 2009 LQCRAIAGIPIPVLQWSHEDGRPFASNIKH--LPGGVLRLSNITT----NDGGSYVCSAV 2062

Query: 89   NSYGTARSRNATLHVAVLREEFRL-EPESK--QSAQGDTVVLECLPPRGSPEPNVYWKKN 145
            NS G   S +AT+++ V      L  P+S       GD V L C    G P+P V W K+
Sbjct: 2063 NSVG---SNSATVYIEVQSVPIILITPKSGILTVKPGDRVRLVC-SATGYPQPTVAWSKH 2118

Query: 146  GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK---- 201
               +    +  +         I  A   D G Y C A NAAG  E  +  +++       
Sbjct: 2119 MNIVPLTTNEVIDTPQKAVYEIYSASPNDEGSYTCHANNAAGIVEERVY-IRVEDSEVYP 2177

Query: 202  ------PYLITGPEDVVAQ------TGSSVTFQCRVGGDPLPDVL--WRRSAGGGNMPLG 247
                  P   T  +D + +       G  V  +C V  +    +   W+R+     +P G
Sbjct: 2178 PCRGDVPCHDTTSDDPIPKDYLRIPNGGKVEMRCHVHDNDGNHIYLDWKRTDHRA-LPNG 2236

Query: 248  RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV--SASGYLTVYDPPSINLSPNSVNVE 305
                + +G L +  V  +  GEY C   +  G +   A  +L V  PP I L P    V 
Sbjct: 2237 --SSVHNGVLIIPAVDKSAAGEYVCSGMDQAGNLLFKAKSHLEVLSPPRIVLIPPRQTVR 2294

Query: 306  SGNVARFTCTATGRPEPTMFWSVEG 330
            SG      C   G    T+ W+  G
Sbjct: 2295 SGESPSIECRTNGDEPMTIEWNAIG 2319



 Score = 52.4 bits (120), Expect = 7e-05
 Identities = 38/133 (28%), Positives = 60/133 (45%), Gaps = 12/133 (9%)

Query: 205  ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
            I GPE  + +TG++V + C         +  +    GG +P GR    + G L + +V +
Sbjct: 1617 IRGPEFQIIETGTTVRYHCSGTSVDNGSLYIKWEKEGGQLPPGRSVDDNHGLLVIRDVKV 1676

Query: 265  ADEGEYSCEAEN-----------SVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313
            +D G Y C+  +           +VGA   S  L +   P   + P S+ V  G+ A F 
Sbjct: 1677 SDSGIYVCQVSDGVHIGYKNVTLTVGAFPQS-LLDIPTAPRTIVIPPSLQVVEGHSAEFR 1735

Query: 314  CTATGRPEPTMFW 326
            C A+G P P + W
Sbjct: 1736 CEASGNPPPQIEW 1748



 Score = 49.2 bits (112), Expect = 7e-04
 Identities = 62/260 (23%), Positives = 102/260 (39%), Gaps = 28/260 (10%)

Query: 5    YVTSGEAPYIIEQPLD--VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI-L 61
            Y+     P I+  P    +TV       L C A G P P + W K   +V   T+  I  
Sbjct: 2073 YIEVQSVPIILITPKSGILTVKPGDRVRLVCSATGYPQPTVAWSKHMNIVPLTTNEVIDT 2132

Query: 62   PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSA 120
            P   ++ +   +    +D G Y C A N+ G    R    +  + +    R +     + 
Sbjct: 2133 PQKAVYEI---YSASPNDEGSYTCHANNAAGIVEERVYIRVEDSEVYPPCRGDVPCHDTT 2189

Query: 121  QGDTVVLECL--PPRGSPEP----------NVY--WKKNGQTLLFDGDSRMHLVDGGNLV 166
              D +  + L  P  G  E           ++Y  WK+     L +G S    V  G L+
Sbjct: 2190 SDDPIPKDYLRIPNGGKVEMRCHVHDNDGNHIYLDWKRTDHRALPNGSS----VHNGVLI 2245

Query: 167  IQDARQTDAGRYQCIARNAAGTRE-SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV 225
            I    ++ AG Y C   + AG     A + L++   P ++  P     ++G S + +CR 
Sbjct: 2246 IPAVDKSAAGEYVCSGMDQAGNLLFKAKSHLEVLSPPRIVLIPPRQTVRSGESPSIECRT 2305

Query: 226  GGDPLPDVLWRRSAGGGNMP 245
             GD    + W  +A G ++P
Sbjct: 2306 NGDEPMTIEW--NAIGRSLP 2323



 Score = 47.2 bits (107), Expect = 0.003
 Identities = 35/96 (36%), Positives = 44/96 (45%), Gaps = 8/96 (8%)

Query: 204 LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVI 263
           L T P + V +    V FQCR  G     V W R   G N+PL       +G L + N+ 
Sbjct: 179 LKTYPSEQVIKESREVVFQCRDEGPLRAKVRWLR---GNNLPLPSGSRDINGRLEIPNIQ 235

Query: 264 LADEGEYSCEAEN---SVGAVSASGYLTV--YDPPS 294
           L   G Y CEA +   S      S YLTV  +DPP+
Sbjct: 236 LNHSGSYICEAVDYPPSTPGQQVSVYLTVEKFDPPA 271



 Score = 47.2 bits (107), Expect = 0.003
 Identities = 50/200 (25%), Positives = 77/200 (38%), Gaps = 12/200 (6%)

Query: 79   DAGVYWCEATNSYGTARSRNATLHVAVLR-EEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
            D+G Y C+   S+G + S    L+V+        +E        GDT+ + C    G+  
Sbjct: 2394 DSGRYICQIQTSHGVS-SDYINLNVSPTPIPAVSVEVSQDPVNIGDTIDIRCACS-GTHN 2451

Query: 138  PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
            P  +W +     L +         G  L + +   +D+G Y+C A    G  +     L 
Sbjct: 2452 PRYHWSRPNHMSLPENAQEY----GNVLRLSNVAVSDSGLYRCTADTPEGVFKQDF-NLV 2506

Query: 198  IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257
            +H         E   A  GSS+   CR   DP     W +   GG +P      + +  L
Sbjct: 2507 VHGGNNDAPAIETKYAPYGSSLEMDCRPNIDPPMKFHWSKL--GGFLPPDAQ--IFESKL 2562

Query: 258  RLDNVILADEGEYSCEAENS 277
            +L NV   D G Y C   N+
Sbjct: 2563 KLINVKAEDAGTYICSVNNN 2582



 Score = 46.4 bits (105), Expect = 0.005
 Identities = 53/198 (26%), Positives = 78/198 (39%), Gaps = 26/198 (13%)

Query: 288  TVYDPPSINL---SPNSVNVESGNVARFTCTATGRPEPTMF--WSVEGNRTIIFPGMSRD 342
            T   PP I +    P    +E+G   R+ C+ T     +++  W  EG +  + PG S D
Sbjct: 1606 TTITPPMILIYIRGPEFQIIETGTTVRYHCSGTSVDNGSLYIKWEKEGGQ--LPPGRSVD 1663

Query: 343  KYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTS------DDDRP 396
              H         +L I D   +DS    VC   +     +    LTV +      D    
Sbjct: 1664 DNHG--------LLVIRDVKVSDS-GIYVCQVSDGVHIGYKNVTLTVGAFPQSLLDIPTA 1714

Query: 397  PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKD 456
            P  I   PS Q +   S A F C A   P P I W      +   +   +  +G  +LK 
Sbjct: 1715 PRTIVIPPSLQVVEGHS-AEFRCEASGNPPPQIEWIRVHGPM---NPEVIVYNGAWILKA 1770

Query: 457  LDKSDSGTYTCVASSRHG 474
            + KSD+  Y C+A +  G
Sbjct: 1771 VSKSDAAEYKCIARNNIG 1788



 Score = 44.4 bits (100), Expect = 0.019
 Identities = 49/213 (23%), Positives = 79/213 (37%), Gaps = 18/213 (8%)

Query: 122  GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
            G  V L+C+      +  ++W ++GQ L     S +  ++   L +   R  D+GRY C 
Sbjct: 2350 GQPVRLQCMVRE---KATIHWVRDGQPL----PSNVR-IEEDYLELPRVRPEDSGRYICQ 2401

Query: 182  ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT----GSSVTFQCRVGGDPLPDVLWRR 237
             + + G     I    +++ P  I      V+Q     G ++  +C   G   P   W R
Sbjct: 2402 IQTSHGVSSDYI---NLNVSPTPIPAVSVEVSQDPVNIGDTIDIRCACSGTHNPRYHWSR 2458

Query: 238  SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
                 +M L          LRL NV ++D G Y C A+   G       L V+   +   
Sbjct: 2459 P---NHMSLPENAQEYGNVLRLSNVAVSDSGLYRCTADTPEGVFKQDFNLVVHGGNNDAP 2515

Query: 298  SPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
            +  +     G+     C     P     WS  G
Sbjct: 2516 AIETKYAPYGSSLEMDCRPNIDPPMKFHWSKLG 2548



 Score = 43.6 bits (98), Expect = 0.034
 Identities = 31/113 (27%), Positives = 46/113 (40%), Gaps = 4/113 (3%)

Query: 175 AGRYQCIARNAAGTRESAI--ATLKIHIKPYLITGPED--VVAQTGSSVTFQCRVGGDPL 230
           A   QCI ++     E     A+ ++   P  I  P    +    G  +T  C   G P 
Sbjct: 368 ASNNQCIPKSYHCDMEKDCLDASDEVGCSPVFIVKPPVPMITLNIGEVLTITCTAIGVPT 427

Query: 231 PDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSA 283
           P++ WR + G          +   G+L   N+   D+G YSCE  N+ G V A
Sbjct: 428 PEINWRLNWGHVPPKCTMTSINGTGTLTCPNIQPEDQGAYSCEGLNNAGFVFA 480



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 20/68 (29%), Positives = 28/68 (41%), Gaps = 1/68 (1%)

Query: 408 TLPIKSMAVFPCTAICTPEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYT 466
           TL I  +    CTAI  P P I W    G    +    ++   GTL   ++   D G Y+
Sbjct: 409 TLNIGEVLTITCTAIGVPTPEINWRLNWGHVPPKCTMTSINGTGTLTCPNIQPEDQGAYS 468

Query: 467 CVASSRHG 474
           C   +  G
Sbjct: 469 CEGLNNAG 476



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 40/184 (21%), Positives = 69/184 (37%), Gaps = 16/184 (8%)

Query: 31   LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
            + C   G+ +P   W +   + + +  +     G +  LR ++  V SD+G+Y C A   
Sbjct: 2442 IRCACSGTHNPRYHWSRPNHMSLPENAQEY---GNV--LRLSNVAV-SDSGLYRCTADTP 2495

Query: 91   YGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
             G  +   N  +H            E+K +  G ++ ++C P    P    +W K G  L
Sbjct: 2496 EGVFKQDFNLVVHGG---NNDAPAIETKYAPYGSSLEMDCRP-NIDPPMKFHWSKLGGFL 2551

Query: 150  LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
              D       +    L + + +  DAG Y C   N     E     +   + PY    P 
Sbjct: 2552 PPDAQ-----IFESKLKLINVKAEDAGTYICSVNNNHENIEIPTVLVVTGVVPYFSQAPR 2606

Query: 210  DVVA 213
              +A
Sbjct: 2607 SFIA 2610


>UniRef50_Q4SPP9 Cluster: Chromosome 16 SCAF14537, whole genome
           shotgun sequence; n=2; cellular organisms|Rep:
           Chromosome 16 SCAF14537, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 838

 Score =  112 bits (269), Expect = 6e-23
 Identities = 76/237 (32%), Positives = 114/237 (48%), Gaps = 16/237 (6%)

Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVN 303
           +G+ +VL +G+L + N  + D G+Y C AEN  G       L+V   PS  L P    + 
Sbjct: 527 MGKYEVLHNGTLSIHNTNIKDRGQYLCTAENDHGMDKLLVTLSVVAYPSRILEPKLRQIK 586

Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
           V +GN A  TC A GRP P++ W +  NRT +  G++ +    +   +G   L I D   
Sbjct: 587 VLAGNTAEVTCKAEGRPTPSISW-ILPNRTQV-RGLNTEWGRVSVTPEG--ALVIKDLSM 642

Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
           ND R    C A N AG      +L V +    PP I+        + +   A+ PCT   
Sbjct: 643 ND-RGHYKCIASNQAGGDIATVQLHVVA---APPGIMEEKRQQVNIGVSQSALLPCTGQG 698

Query: 424 TPEPIIAW------YFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
            P+P I W      +   + L  N R  V  +GTL ++++ ++DSG Y C+A+S  G
Sbjct: 699 RPQPTIHWVLHDGSHLPSKRLTSNTRTLVHENGTLYIENVTQADSGKYECIATSSTG 755



 Score = 98.3 bits (234), Expect = 1e-18
 Identities = 79/309 (25%), Positives = 120/309 (38%), Gaps = 15/309 (4%)

Query: 146 GQTLLFDGD-SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL 204
           G +++  G   +  ++  G L I +    D G+Y C A N  G  +  + TL +   P  
Sbjct: 518 GNSIIIKGKMGKYEVLHNGTLSIHNTNIKDRGQYLCTAENDHGM-DKLLVTLSVVAYPSR 576

Query: 205 ITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGGGNMPLGRVKVLDDGSLR 258
           I  P+   +    G++    C+  G P P + W    R    G N   GRV V  +G+L 
Sbjct: 577 ILEPKLRQIKVLAGNTAEVTCKAEGRPTPSISWILPNRTQVRGLNTEWGRVSVTPEGALV 636

Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYL-TVYDPPSI-NLSPNSVNVESGNVARFTCTA 316
           + ++ + D G Y C A N  G   A+  L  V  PP I       VN+     A   CT 
Sbjct: 637 IKDLSMNDRGHYKCIASNQAGGDIATVQLHVVAAPPGIMEEKRQQVNIGVSQSALLPCTG 696

Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
            GRP+PT+ W +     +  P         T V +  T+   N T  +  +    C A +
Sbjct: 697 QGRPQPTIHWVLHDGSHL--PSKRLTSNTRTLVHENGTLYIENVTQADSGK--YECIATS 752

Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436
             GS   R  + V       P I+        L         C+A+  P P I W    +
Sbjct: 753 STGSE-KRVVILVVEKAASAPHIVETFQRKMELFFGDQLRLNCSAVGDPRPKIMWRLPSK 811

Query: 437 ALIQNHRRN 445
           A++     N
Sbjct: 812 AMLDQGHSN 820



 Score = 70.9 bits (166), Expect = 2e-10
 Identities = 59/239 (24%), Positives = 105/239 (43%), Gaps = 24/239 (10%)

Query: 14  IIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-----SILPAGGLF 67
           I+E  L  + V     A + C+A G P+P+I W       V   +      S+ P G L 
Sbjct: 577 ILEPKLRQIKVLAGNTAEVTCKAEGRPTPSISWILPNRTQVRGLNTEWGRVSVTPEGALV 636

Query: 68  FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GDT 124
               +     +D G Y C A+N  G      AT+ + V+     +  E +Q        +
Sbjct: 637 IKDLS----MNDRGHYKCIASNQAG---GDIATVQLHVVAAPPGIMEEKRQQVNIGVSQS 689

Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLL----FDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
            +L C   +G P+P ++W  +  + L       ++R  + + G L I++  Q D+G+Y+C
Sbjct: 690 ALLPC-TGQGRPQPTIHWVLHDGSHLPSKRLTSNTRTLVHENGTLYIENVTQADSGKYEC 748

Query: 181 IARNAAGTRESAIATL--KIHIKPYLI-TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
           IA ++ G+ +  +  +  K    P+++ T    +    G  +   C   GDP P ++WR
Sbjct: 749 IATSSTGSEKRVVILVVEKAASAPHIVETFQRKMELFFGDQLRLNCSAVGDPRPKIMWR 807



 Score = 41.9 bits (94), Expect = 0.10
 Identities = 40/149 (26%), Positives = 61/149 (40%), Gaps = 15/149 (10%)

Query: 16  EQPLDVTVARHQPATLNCRAGGSPSPAIRW--YKGGVL----VVSDTHRSILPAGGLFFL 69
           E+   V +   Q A L C   G P P I W  + G  L    + S+T   +   G L+  
Sbjct: 677 EKRQQVNIGVSQSALLPCTGQGRPQPTIHWVLHDGSHLPSKRLTSNTRTLVHENGTLYIE 736

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GDTVV 126
             T     +D+G Y C AT+S G+ + R   L V        +    ++  +   GD + 
Sbjct: 737 NVT----QADSGKYECIATSSTGSEK-RVVILVVEKAASAPHIVETFQRKMELFFGDQLR 791

Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDS 155
           L C    G P P + W+   + +L  G S
Sbjct: 792 LNC-SAVGDPRPKIMWRLPSKAMLDQGHS 819


>UniRef50_A7RQE6 Cluster: Predicted protein; n=3; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 807

 Score =  112 bits (269), Expect = 6e-23
 Identities = 103/346 (29%), Positives = 154/346 (44%), Gaps = 45/346 (13%)

Query: 158 HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL-----------KIHIKPYLIT 206
           H +    LVI++ R +D G Y C ARN  G R+  +  +           + HI   ++ 
Sbjct: 366 HPITQSTLVIKETRGSDTGTYTCRARNMMGARDYHVDLIVQGNQSKSQKHRTHIPVAIVV 425

Query: 207 GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILAD 266
            PE+     G+ V+  C   G P P + W R   GG MP+    V  +G L + N+  + 
Sbjct: 426 RPENQTELEGNEVSLNCNASGIPAPSITWYRQ-DGGYMPVNHRVV--NGDLIISNITKSL 482

Query: 267 EGEYSCEAENSVGAVSASGYLTVYDPPSI-NLSPNSVNVESGNVARFTCTATGRPEPTMF 325
           EG Y CEA+N +GA +    + V   P + +L    + +   + A   CT+TG P P + 
Sbjct: 483 EGTYVCEAKNVLGARTKEATVLVNIAPRLTSLHKTPLTIVENSTAVVPCTSTGFPTPEIS 542

Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385
           WS  GN       +SR  Y + A       L I D   +D R T VCSA N  G   V G
Sbjct: 543 WSKIGNSM----DVSRMSYDSQA-------LIIKDVRYSD-RGTYVCSATNEEGR--VNG 588

Query: 386 KLT----VTSDDDRPPPIITNG--PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI 439
            +T    V     + P  I  G  P+++ L ++   VF       P P I W   G AL 
Sbjct: 589 TVTVIVQVAPRVHQQPKAIEFGYRPASKELQLR---VFG-----FPPPNITW--SGPALR 638

Query: 440 QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485
            +  R   +DG+L++   +  DSG Y  +  +  G+ V    L+V+
Sbjct: 639 HSKSRVNQSDGSLMIMRTEFRDSGEYQAIVKNVVGQAVIRTFLVVN 684



 Score =  103 bits (247), Expect = 3e-20
 Identities = 115/397 (28%), Positives = 161/397 (40%), Gaps = 42/397 (10%)

Query: 14  IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK--GGVLVVSDTHRSILPAGGLFFLRA 71
           I+ +P + T       +LNC A G P+P+I WY+  GG + V+  HR +   G L     
Sbjct: 423 IVVRPENQTELEGNEVSLNCNASGIPAPSITWYRQDGGYMPVN--HRVV--NGDLIISNI 478

Query: 72  THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
           T     S  G Y CEA N  G AR++ AT+ V +      L        +  T V+ C  
Sbjct: 479 T----KSLEGTYVCEAKNVLG-ARTKEATVLVNIAPRLTSLHKTPLTIVENSTAVVPC-T 532

Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
             G P P + W K G ++     SRM   D   L+I+D R +D G Y C A N  G R +
Sbjct: 533 STGFPTPEISWSKIGNSM---DVSRMS-YDSQALIIKDVRYSDRGTYVCSATNEEG-RVN 587

Query: 192 AIATLKIHIKPYLITGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250
              T+ + + P +   P+ +      +S   Q RV G P P++ W  S         RV 
Sbjct: 588 GTVTVIVQVAPRVHQQPKAIEFGYRPASKELQLRVFGFPPPNITW--SGPALRHSKSRVN 645

Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV-----YDPPSINLSPNSVNVE 305
              DGSL +      D GEY    +N VG      +L V     +    I+L    V   
Sbjct: 646 -QSDGSLMIMRTEFRDSGEYQAIVKNVVGQAVIRTFLVVNQGDFFKVFIIDLGQQLVRHS 704

Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFP----GMSRDKYHATAVFDGV-------- 353
            G              PT   ++  N T + P    G      + T + + +        
Sbjct: 705 WGMFPLLLVAPLLMSFPTTPLTIVENSTAVVPCISTGFPAPVINWTKIENSMDPSRMSYD 764

Query: 354 -TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389
              LTI D   +D   T VCSA N AG   V G +TV
Sbjct: 765 SRALTIKDVRLSDV-GTYVCSATNVAGQ--VNGNVTV 798



 Score = 88.6 bits (210), Expect = 9e-16
 Identities = 102/424 (24%), Positives = 170/424 (40%), Gaps = 39/424 (9%)

Query: 78  SDAGVYWCEATNSYGTARSRNATL-----------HVAVLREEFRLEPESKQSAQGDTVV 126
           SD G Y C A N  G AR  +  L           H   +     + PE++   +G+ V 
Sbjct: 381 SDTGTYTCRARNMMG-ARDYHVDLIVQGNQSKSQKHRTHIPVAIVVRPENQTELEGNEVS 439

Query: 127 LECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
           L C    G P P++ W +++G  +  +     H V  G+L+I +  ++  G Y C A+N 
Sbjct: 440 LNC-NASGIPAPSITWYRQDGGYMPVN-----HRVVNGDLIISNITKSLEGTYVCEAKNV 493

Query: 186 AGTRESAIATLKIHIKPYLIT-GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
            G R    AT+ ++I P L +     +     S+    C   G P P++ W  S  G +M
Sbjct: 494 LGARTKE-ATVLVNIAPRLTSLHKTPLTIVENSTAVVPCTSTGFPTPEISW--SKIGNSM 550

Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
            + R+   D  +L + +V  +D G Y C A N  G V+ +  + V   P ++  P ++  
Sbjct: 551 DVSRMS-YDSQALIIKDVRYSDRGTYVCSATNEEGRVNGTVTVIVQVAPRVHQQPKAIEF 609

Query: 305 ESGNVAR-FTCTATGRPEPTMFWSVEGNR------------TIIFPGMSRDKYHATAVFD 351
                ++       G P P + WS    R             +I     RD     A+  
Sbjct: 610 GYRPASKELQLRVFGFPPPNITWSGPALRHSKSRVNQSDGSLMIMRTEFRDSGEYQAIVK 669

Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
            V    +  T    ++       +   G   VR    +       P +++   +  T+  
Sbjct: 670 NVVGQAVIRTFLVVNQGDFFKVFIIDLGQQLVRHSWGMFPLLLVAPLLMSFPTTPLTIVE 729

Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
            S AV PC +   P P+I W     ++  +  R   +   L +KD+  SD GTY C A++
Sbjct: 730 NSTAVVPCISTGFPAPVINWTKIENSM--DPSRMSYDSRALTIKDVRLSDVGTYVCSATN 787

Query: 472 RHGK 475
             G+
Sbjct: 788 VAGQ 791


>UniRef50_O15146 Cluster: Muscle, skeletal receptor tyrosine protein
           kinase precursor; n=53; Euteleostomi|Rep: Muscle,
           skeletal receptor tyrosine protein kinase precursor -
           Homo sapiens (Human)
          Length = 869

 Score =  112 bits (269), Expect = 6e-23
 Identities = 81/275 (29%), Positives = 129/275 (46%), Gaps = 16/275 (5%)

Query: 10  EAPYIIEQPLDVTVAR-HQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLF 67
           +AP +I  PL+   A   + AT  C     P P I W +  +L+ + DT  SI   G L 
Sbjct: 26  KAP-VITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLL 84

Query: 68  FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
            + +      SD G+Y C A N  G A      L V  ++ +    P + +  +G   VL
Sbjct: 85  TILSVED---SDDGIYCCTANNGVGGAVESCGALQVK-MKPKITRPPINVKIIEGLKAVL 140

Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
            C    G+P+P+V W K    L    +SR+ +++ G+L I + ++ DAG+Y+C+A+N+ G
Sbjct: 141 PCTT-MGNPKPSVSWIKGDSPLR--ENSRIAVLESGSLRIHNVQKEDAGQYRCVAKNSLG 197

Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
           T  S +  L++ +   ++  PE      GS VT  C   G P+P + W  +    +    
Sbjct: 198 TAYSKVVKLEVEVFARILRAPESHNVTFGSFVTLHCTATGIPVPTITWIENGNAVSSGSI 257

Query: 248 RVKVLD---DGSLRLDNVILADEGEYSCEAENSVG 279
           +  V D   D  L+L    +   G Y+C A N  G
Sbjct: 258 QESVKDRVIDSRLQL---FITKPGLYTCIATNKHG 289



 Score = 91.5 bits (217), Expect = 1e-16
 Identities = 77/284 (27%), Positives = 122/284 (42%), Gaps = 17/284 (5%)

Query: 195 TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254
           T K+   P + T  E V A      TF C V   P P++ W R+     +   R  + ++
Sbjct: 21  TEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIREN 80

Query: 255 GSL-RLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSPNSVNVESGNVARF 312
           G L  + +V  +D+G Y C A N VG AV + G L V   P I   P +V +  G  A  
Sbjct: 81  GQLLTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMKPKITRPPINVKIIEGLKAVL 140

Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
            CT  G P+P++ W ++G+  +      R+      +  G   L I++  K D+     C
Sbjct: 141 PCTTMGNPKPSVSW-IKGDSPL------RENSRIAVLESG--SLRIHNVQKEDA-GQYRC 190

Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
            A N  G+++ +    V   +      I   P +  +   S     CTA   P P I W 
Sbjct: 191 VAKNSLGTAYSK----VVKLEVEVFARILRAPESHNVTFGSFVTLHCTATGIPVPTITWI 246

Query: 433 FEGEALIQNHRRNVTNDGTLVLK-DLDKSDSGTYTCVASSRHGK 475
             G A+     +    D  +  +  L  +  G YTC+A+++HG+
Sbjct: 247 ENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGE 290



 Score = 68.1 bits (159), Expect = 1e-09
 Identities = 67/258 (25%), Positives = 109/258 (42%), Gaps = 19/258 (7%)

Query: 281 VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340
           V+ SG   +   P I     +V+     VA F C     P+P + W+    R  I   + 
Sbjct: 16  VAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEISWT----RNKILIKLF 71

Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR-GKLTVTSDDDRPPPI 399
             +Y        +T+L++ D+D         C+A N  G +    G L V     +  P 
Sbjct: 72  DTRYSIRENGQLLTILSVEDSDDG----IYCCTANNGVGGAVESCGALQV-----KMKPK 122

Query: 400 ITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDK 459
           IT  P N  +     AV PCT +  P+P ++W      L +N R  V   G+L + ++ K
Sbjct: 123 ITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVLESGSLRIHNVQK 182

Query: 460 SDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTS 519
            D+G Y CVA +  G   +S  + ++  +   I   RA +  ++       +    T   
Sbjct: 183 EDAGQYRCVAKNSLGT-AYSKVVKLEVEVFARI--LRAPESHNVTFGSFVTLHCTATGIP 239

Query: 520 V-TLSWSQN-NKIGSSSI 535
           V T++W +N N + S SI
Sbjct: 240 VPTITWIENGNAVSSGSI 257


>UniRef50_Q13332 Cluster: Receptor-type tyrosine-protein phosphatase
           S precursor; n=34; Craniata|Rep: Receptor-type
           tyrosine-protein phosphatase S precursor - Homo sapiens
           (Human)
          Length = 1948

 Score =  111 bits (268), Expect = 8e-23
 Identities = 159/625 (25%), Positives = 236/625 (37%), Gaps = 80/625 (12%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI-LPAGGLFF 68
           E P  I++P D        A+  C+A G P P + W K G  V S    +I         
Sbjct: 31  EPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAV 90

Query: 69  LRATHGRVHSDAGVYWCEATNSYG--TARSRNATLHVAVLREEFR---LEPESKQSAQGD 123
           LR    R   D  VY C A NS G  T  ++   L    L   F    + P+ K   +  
Sbjct: 91  LRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTR 150

Query: 124 TVVLECLPPRGSPEPNVYWKK----------NGQTLLFDGDSRMHLVDGGNLVIQDARQT 173
           T  + C    G+P+P + W K          NG+      ++       G L I+ + +T
Sbjct: 151 TATMLCAAS-GNPDPEITWFKDFLPVDPSASNGRIKQLRSETFESTPIRGALQIESSEET 209

Query: 174 DAGRYQCIARNAAGTRESAIATLKI-------HIKPYLITGPEDVVAQTGSSVTFQCRVG 226
           D G+Y+C+A N+AG R S+ A L +        + P     P       G +V   C   
Sbjct: 210 DQGKYECVATNSAGVRYSSPANLYVRELREVRRVAPRFSILPMSHEIMPGGNVNITCVAV 269

Query: 227 GDPLPDVLWRRSAGG----GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVS 282
           G P+P V W + A       +MP+GR        L L +V   D   Y+C A +S+G + 
Sbjct: 270 GSPMPYVKWMQGAEDLTPEDDMPVGR------NVLELTDV--KDSANYTCVAMSSLGVIE 321

Query: 283 ASGYLTVYDPPSINLSPNSVNVESGNVARFTCT-ATGRPEPTMFWSVEGNRTIIFPGMSR 341
           A   +TV   P    +P +  V        T T  +G P+P  ++ +E      +   S+
Sbjct: 322 AVAQITVKSLPK---APGTPMVTENTATSITITWDSGNPDPVSYYVIE------YKSKSQ 372

Query: 342 DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401
           D  +        T  +I     N S   I  SAVN  G      +  VT   ++ P    
Sbjct: 373 DGPYQIKEDITTTRYSIGGLSPN-SEYEIWVSAVNSIGQG-PPSESVVTRTGEQAPASAP 430

Query: 402 NGPSNQTLPIKSMAVFPCTAICTPEPIIAWY-----FEGEALIQNHRRNVTNDGTLVLKD 456
                + L   +M V        P  +I  Y      E E  + N +++  +D  L    
Sbjct: 431 RNVQARMLSATTMIV-QWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVG 489

Query: 457 LDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVT 516
               D  TYT          V +   + D P++  I   +      +PG P        +
Sbjct: 490 SLLEDE-TYTV--------RVLAFTSVGDGPLSDPI---QVKTQQGVPGQPMNLRAEARS 537

Query: 517 DTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKS 576
           +TS+TLSWS   +    SI+ Y  E+  RE   G    R              T YVV+ 
Sbjct: 538 ETSITLSWSPPRQ---ESIIKY--ELLFREGDHGREVGRTFD---------PTTSYVVED 583

Query: 577 LIPGITYMFIVRTENSHGLSGPSPV 601
           L P   Y F +   +  GL   +PV
Sbjct: 584 LKPNTEYAFRLAARSPQGLGAFTPV 608



 Score =  107 bits (258), Expect = 1e-21
 Identities = 157/642 (24%), Positives = 248/642 (38%), Gaps = 83/642 (12%)

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LR 258
           P  I  P+D +  +G   +F C+  GDP P V W +     N         D+ +   LR
Sbjct: 33  PRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLR 92

Query: 259 LDNVILA-DEGEYSCEAENSVGAVSASGYLTVYDP-------PSINLSPNSVNVESGNVA 310
           +  +    DE  Y C A+NSVG ++    LTV          P+I++ P    VE    A
Sbjct: 93  IQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTA 152

Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV---LTINDTDKNDSR 367
              C A+G P+P + W  +           R K   +  F+   +   L I  +++ D +
Sbjct: 153 TMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSETFESTPIRGALQIESSEETD-Q 211

Query: 368 NTIVCSAVNYAG---SSFVRGKLTVTSDDDRPPPIITNGP-SNQTLPIKSMAVFPCTAIC 423
               C A N AG   SS     +    +  R  P  +  P S++ +P  ++ +  C A+ 
Sbjct: 212 GKYECVATNSAGVRYSSPANLYVRELREVRRVAPRFSILPMSHEIMPGGNVNI-TCVAVG 270

Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
           +P P + W    E L       V   G  VL+  D  DS  YTCVA S  G         
Sbjct: 271 SPMPYVKWMQGAEDLTPEDDMPV---GRNVLELTDVKDSANYTCVAMSSLGV-------- 319

Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543
                   I       V SLP  P  P+    T TS+T++W   N      +  Y +E  
Sbjct: 320 --------IEAVAQITVKSLPKAPGTPMVTENTATSITITWDSGNP---DPVSYYVIEYK 368

Query: 544 SRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
           S+          +  G   I   +  T Y +  L P   Y   V   NS G  GP   S 
Sbjct: 369 SK----------SQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIG-QGPPSESV 417

Query: 604 SVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEG 663
               G+ + +         + + R    T  IV+  E  P++   +   + +  +Y +E 
Sbjct: 418 VTRTGEQAPA-----SAPRNVQARMLSATTMIVQWEE--PVEPNGLIRGYRV--YYTMEP 468

Query: 664 LFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRV 723
                 P+ N    ++   +   +D     + SL +   Y   ++ F    +G  S+   
Sbjct: 469 E----HPVGN----WQKHNV---DDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQ 517

Query: 724 AQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMV 783
            +T   VP G P+N+     + T++ L WSPP    Q  II  Y ++    D        
Sbjct: 518 VKTQQGVP-GQPMNLRAEARSETSITLSWSPPR---QESIIK-YELLFREGDHGRE---- 568

Query: 784 AINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
            +  T    TS ++ +L     Y+ ++AA +  GLG F+  V
Sbjct: 569 -VGRTFDPTTSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVV 609



 Score = 54.4 bits (125), Expect = 2e-05
 Identities = 39/140 (27%), Positives = 65/140 (46%), Gaps = 10/140 (7%)

Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
           + +L K+T+Y    +   +   G  S+  V +T +DVP  PP  +E   LN T + + W 
Sbjct: 683 LEALEKWTQYRITTVAHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWR 742

Query: 754 PPELQLQNGIITGYNVVVNWLD------VPANKSMVAIN----TTVHQATSLIMTNLTSG 803
            P    Q+G I GY V    ++       P  K ++  +    T       +++TNL   
Sbjct: 743 SPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQWETDDTAEYEMVITNLQPE 802

Query: 804 VSYSVQIAAETIIGLGPFSQ 823
            +YS+ +AA T+ G G  S+
Sbjct: 803 TAYSITVAAYTMKGDGARSK 822



 Score = 53.2 bits (122), Expect = 4e-05
 Identities = 46/187 (24%), Positives = 78/187 (41%), Gaps = 10/187 (5%)

Query: 670 PLDNITIEYEMKT------ILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRV 723
           P+    IEY+ K+      I      + + I  L   ++YE ++       +G PS S V
Sbjct: 359 PVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVV 418

Query: 724 AQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMV 783
            +T +  P   P N++  +L+ TT+ ++W  P     NG+I GY V   +   P +    
Sbjct: 419 TRTGEQAPASAPRNVQARMLSATTMIVQWEEP--VEPNGLIRGYRVY--YTMEPEHPVGN 474

Query: 784 AINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYP 843
                V  +    + +L    +Y+V++ A T +G GP S  +         G  +  R  
Sbjct: 475 WQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAE 534

Query: 844 MNGEVSI 850
              E SI
Sbjct: 535 ARSETSI 541



 Score = 52.0 bits (119), Expect = 1e-04
 Identities = 36/143 (25%), Positives = 61/143 (42%), Gaps = 5/143 (3%)

Query: 690 SGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVH 749
           + + +  L+  T+Y F L     +  G  +     +TL   P  PP +++   + +T + 
Sbjct: 577 TSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAIL 636

Query: 750 LKWSPPELQLQNGIITGYNVVVNWL--DVPANKSMVAINTTVHQATSLIMTNLTSGVSYS 807
           + W PP  +  NG + GY+V    L  + P  K +  I  T    T +++  L     Y 
Sbjct: 637 VSWRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPT---TTQILLEALEKWTQYR 693

Query: 808 VQIAAETIIGLGPFSQKVYFNID 830
           +   A T +G GP S  V    D
Sbjct: 694 ITTVAHTEVGPGPESSPVVVRTD 716



 Score = 45.6 bits (103), Expect = 0.008
 Identities = 39/136 (28%), Positives = 60/136 (44%), Gaps = 9/136 (6%)

Query: 728  DDVPDGPPINIEMF-ILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDV--PANKSMVA 784
            +D P G P  +E     +  TV L+W PP    +NG I  Y V V       PA ++ + 
Sbjct: 925  EDTPRGHPQILEAAGNASAGTVLLRWLPPVPAERNGAIVKYTVAVREAGALGPARETELP 984

Query: 785  INTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPM 844
                     +L +  L    +Y +Q+ A T  G GPFS  V +    R+   D +S  P 
Sbjct: 985  AAAEPGAENALTLQGLKPDTAYDLQVRAHTRRGPGPFSPPVRY----RTFLRDQVS--PK 1038

Query: 845  NGEVSIVAGDFVMETW 860
            N +V ++    V+ +W
Sbjct: 1039 NFKVKMIMKTSVLLSW 1054


>UniRef50_Q15746 Cluster: Myosin light chain kinase, smooth muscle;
           n=40; Theria|Rep: Myosin light chain kinase, smooth
           muscle - Homo sapiens (Human)
          Length = 1914

 Score =  111 bits (268), Expect = 8e-23
 Identities = 104/353 (29%), Positives = 140/353 (39%), Gaps = 42/353 (11%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLR 70
           P    +P    V  +Q     C   G P P + W+  G  V   +    +    G  +L 
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473

Query: 71  ATHGRVHSDAGVYWCEATNSYGTARSRNATLHV---AVLREEFRLEPESKQSA--QGDTV 125
               R   D+G Y C A+N+ G   S + TL V   AV+          K  A  +G   
Sbjct: 474 LLKARTR-DSGTYSCTASNAQGQV-SCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDF 531

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARN 184
           VL+C   RG+P P + W  NGQ + +   +R     G   L IQDA   D G Y C+A N
Sbjct: 532 VLQC-SVRGTPVPRITWLLNGQPIQY---ARSTCEAGVAELHIQDALPEDHGTYTCLAEN 587

Query: 185 AAGTRESAIATLKIHIK-------------------PYLITGPEDVVAQTGSSVTFQCRV 225
           A G + S  A + +H K                   P  + G  D+    GS VT   +V
Sbjct: 588 ALG-QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQV 646

Query: 226 GGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVS 282
            G+P P+V+W  + G              G   SL +  V   D G Y+CEA NS G V 
Sbjct: 647 SGNPPPEVIWLHN-GNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVR 705

Query: 283 ASGYLTVYDP-----PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
               LTV +P     P     P SV    G     +C   G P PT+ W  +G
Sbjct: 706 TQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDG 758



 Score =  104 bits (249), Expect = 2e-20
 Identities = 103/400 (25%), Positives = 163/400 (40%), Gaps = 45/400 (11%)

Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LV 166
           +F  +P+S++  +  TV   C    G P+P V W   G  +     S     D G+  L 
Sbjct: 415 KFESKPQSQEVKENQTVKFRC-EVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473

Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATLKIH------IKPYLITGPEDVVAQTGSSVT 220
           +  AR  D+G Y C A NA G + S   TL++       + P   +  +D     G    
Sbjct: 474 LLKARTRDSGTYSCTASNAQG-QVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFV 532

Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSV 278
            QC V G P+P + W  +  G  +   R    + G   L + + +  D G Y+C AEN++
Sbjct: 533 LQCSVRGTPVPRITWLLN--GQPIQYAR-STCEAGVAELHIQDALPEDHGTYTCLAENAL 589

Query: 279 GAVSASGYLTVYD-------------PPSINLSP------NSVNVESGNVARFTCTATGR 319
           G VS S ++TV++              PS   +P      + + V  G+    T   +G 
Sbjct: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649

Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379
           P P + W   GN          + +H        + L I +    D+  T  C A N AG
Sbjct: 650 PPPEVIWLHNGNEI-----QESEDFHFEQRGTQHS-LWIQEVFPEDT-GTYTCEAWNSAG 702

Query: 380 SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI 439
               +  LTV    D   P   + P + T  +    +  C     P P + W  +G+AL 
Sbjct: 703 EVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALC 762

Query: 440 QN--HRRNVTNDG--TLVLKDLDKSDSGTYTCVASSRHGK 475
           ++  H   + N+   TLVLK +    +G Y  +  +R G+
Sbjct: 763 KDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802



 Score = 78.2 bits (184), Expect = 1e-12
 Identities = 88/289 (30%), Positives = 116/289 (40%), Gaps = 32/289 (11%)

Query: 20  DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
           D  V   Q   L C   G+P P I W   G  +     RS   AG           +  D
Sbjct: 522 DCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI--QYARSTCEAGVAEL--HIQDALPED 577

Query: 80  AGVYWCEATNSYGTAR-SRNATLHV--AVLREEFRLE-PESKQSA----QG--DTVVLE- 128
            G Y C A N+ G    S   T+H   +  + E+ L    SK +A    QG  D  V++ 
Sbjct: 578 HGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDG 637

Query: 129 -----CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG---NLVIQDARQTDAGRYQC 180
                 +   G+P P V W  NG  +    D   H    G   +L IQ+    D G Y C
Sbjct: 638 SQVTMTVQVSGNPPPEVIWLHNGNEIQESED--FHFEQRGTQHSLWIQEVFPEDTGTYTC 695

Query: 181 IARNAAG-TRESAIATLKI-H--IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
            A N+AG  R  A+ T++  H   +P+ I+ P  V A  G SV   C + GDP P V W 
Sbjct: 696 EAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWL 755

Query: 237 RSAGGGNMPLGRVKVL---DDGSLRLDNVILADEGEYSCEAENSVGAVS 282
           R         G  +VL   D  +L L  V     G+Y    +N VG  S
Sbjct: 756 RDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804



 Score = 68.5 bits (160), Expect = 1e-09
 Identities = 78/312 (25%), Positives = 113/312 (36%), Gaps = 36/312 (11%)

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GS--LR 258
           P   + P+    +   +V F+C V G P P+V W           G ++V +D GS  L 
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473

Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN------SVNVESGNVARF 312
           L      D G YSC A N+ G VS S  L V     + ++P+         V  G     
Sbjct: 474 LLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533

Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
            C+  G P P + W + G            +Y  +    GV  L I D    D   T  C
Sbjct: 534 QCSVRGTPVPRITWLLNGQPI---------QYARSTCEAGVAELHIQDALPED-HGTYTC 583

Query: 373 SAVNYAGSSFVRGKLTV--TSDDDRPPPIITNGPSNQTLPI------------KSMAVFP 418
            A N  G       +TV       +   ++   PS  T PI             S     
Sbjct: 584 LAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT 643

Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHGK 475
                 P P + W   G  + ++   +    GT   L ++++   D+GTYTC A +  G+
Sbjct: 644 VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGE 703

Query: 476 YVWSGALLVDSP 487
                 L V  P
Sbjct: 704 VRTQAVLTVQEP 715



 Score = 56.0 bits (129), Expect = 6e-06
 Identities = 47/183 (25%), Positives = 76/183 (41%), Gaps = 9/183 (4%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
           AP  ++   D+ V      T+  +  G+P P + W   G  +           G    L 
Sbjct: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLW 681

Query: 71  ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE----FRLEPESKQSAQGDTVV 126
                   D G Y CEA NS G  R++ A L V    +     F  +P S  ++ G +V+
Sbjct: 682 IQEV-FPEDTGTYTCEAWNSAGEVRTQ-AVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 739

Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGD--SRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
           + C    G P P V+W ++G+ L  D      +   D   LV++  +   AG+Y+ + +N
Sbjct: 740 ISC-AIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 798

Query: 185 AAG 187
             G
Sbjct: 799 RVG 801



 Score = 54.8 bits (126), Expect = 1e-05
 Identities = 43/169 (25%), Positives = 76/169 (44%), Gaps = 12/169 (7%)

Query: 457  LDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVT 516
            ++ S++G+   + ++R  ++     LLV++ +           V     P   P   ++ 
Sbjct: 1286 VENSENGSKLTILAARQ-EHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIR 1344

Query: 517  DTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKS 576
             +S+TLSW  ++  G S++  Y +E++     S N T      W  +A     T + V+ 
Sbjct: 1345 SSSLTLSWYGSSYDGGSAVQSYSIEIWD----SANKT------WKELAT-CRSTSFNVQD 1393

Query: 577  LIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTE 625
            L+P   Y F VR  N +G S PS  S+  TVG+      +   VS+  E
Sbjct: 1394 LLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDE 1442



 Score = 52.8 bits (121), Expect = 5e-05
 Identities = 31/101 (30%), Positives = 52/101 (51%), Gaps = 3/101 (2%)

Query: 192  AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW-RRSAGGGNMPLGRVK 250
            A+A  K H+KPY      D+    GS+  F C++ G P P+V+W +           ++ 
Sbjct: 1799 AVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID 1858

Query: 251  VLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
              +DG  SL + +V   D+ +Y+C+A NS+G  + +  L V
Sbjct: 1859 YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899



 Score = 48.8 bits (111), Expect = 9e-04
 Identities = 35/114 (30%), Positives = 55/114 (48%), Gaps = 7/114 (6%)

Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
           I++ +     S + ++ +   P  I  P ++  + G++  F+ RV G P P V W R+  
Sbjct: 12  ISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRN-- 69

Query: 241 GGNMPLGRVKVLDDG-----SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
           G  +  G   +LD G     SL +  V   D G+Y+CEA N  GA   +  LTV
Sbjct: 70  GQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123



 Score = 46.0 bits (104), Expect = 0.006
 Identities = 29/86 (33%), Positives = 40/86 (46%), Gaps = 3/86 (3%)

Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVI 167
           F L P +    +G T   E    RG PEP V W +NGQ +   G   +     G  +LVI
Sbjct: 35  FILPPRNLCIKEGATAKFEGRV-RGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVI 93

Query: 168 QDARQTDAGRYQCIARNAAGTRESAI 193
               + D G+Y C A N +G R+  +
Sbjct: 94  HAVHEEDRGKYTCEATNGSGARQVTV 119



 Score = 45.6 bits (103), Expect = 0.008
 Identities = 31/96 (32%), Positives = 39/96 (40%), Gaps = 3/96 (3%)

Query: 9   GEAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
           GE P      L  V V   Q    +C+  G P P + W KG V +      S+    G+ 
Sbjct: 157 GECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQ 216

Query: 68  FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103
            L   HG    D GVY C   N  G A S +A L +
Sbjct: 217 VLE-IHGVNQDDVGVYTCLVVNGSGKA-SMSAELSI 250



 Score = 45.2 bits (102), Expect = 0.011
 Identities = 32/98 (32%), Positives = 43/98 (43%), Gaps = 7/98 (7%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG--GLF 67
           EAP  I  P ++ +     A    R  G P P + W++ G  + S   R +L  G  G F
Sbjct: 31  EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSG-GRFLLDCGIRGTF 89

Query: 68  FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV 105
            L   H     D G Y CEATN  G   +R  T+ + V
Sbjct: 90  SL-VIHAVHEEDRGKYTCEATNGSG---ARQVTVELTV 123



 Score = 45.2 bits (102), Expect = 0.011
 Identities = 31/116 (26%), Positives = 50/116 (43%), Gaps = 6/116 (5%)

Query: 183  RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
            R  AGT ++   +      P      +DV    G  +  QC+V  DP   ++W  +  G 
Sbjct: 1079 RGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIW--TLNGK 1136

Query: 243  NMPLGRVKVLD-DGSL---RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
             +   +  +L  +GSL    ++  +  D G Y C A+N  G    S  +TV D P+
Sbjct: 1137 TLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192



 Score = 42.3 bits (95), Expect = 0.078
 Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 7/102 (6%)

Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
           PP        V V+ G + RF+C  TGRP+P + W ++GN     P +      + +  +
Sbjct: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTW-LKGN----VP-LQPSARVSVSEKN 213

Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
           G+ VL I+  +++D      C  VN +G + +  +L++   D
Sbjct: 214 GMQVLEIHGVNQDDV-GVYTCLVVNGSGKASMSAELSIQGLD 254



 Score = 42.3 bits (95), Expect = 0.078
 Identities = 31/94 (32%), Positives = 41/94 (43%), Gaps = 10/94 (10%)

Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGS---LRLDNVIL 264
           VV + G    F C++ G P P V W +    GN+PL    RV V +      L +  V  
Sbjct: 170 VVVKEGQMGRFSCKITGRPQPQVTWLK----GNVPLQPSARVSVSEKNGMQVLEIHGVNQ 225

Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
            D G Y+C   N  G  S S  L++    S N S
Sbjct: 226 DDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259



 Score = 41.1 bits (92), Expect = 0.18
 Identities = 19/62 (30%), Positives = 29/62 (46%), Gaps = 1/62 (1%)

Query: 9   GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT-HRSILPAGGLF 67
           G  P+ I +P  VT +  Q   ++C   G P P + W + G  +  DT H  +L    +F
Sbjct: 718 GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF 777

Query: 68  FL 69
            L
Sbjct: 778 TL 779



 Score = 40.7 bits (91), Expect = 0.24
 Identities = 29/104 (27%), Positives = 43/104 (41%), Gaps = 4/104 (3%)

Query: 386 KLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRR 444
           ++ +    D   P   + P +Q +       F C     P+P +AW+ EG  +  Q    
Sbjct: 402 RIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSI 461

Query: 445 NVTNDG---TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485
            V  D     L L      DSGTY+C AS+  G+   S  L V+
Sbjct: 462 EVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVE 505



 Score = 37.5 bits (83), Expect = 2.2
 Identities = 27/99 (27%), Positives = 42/99 (42%), Gaps = 6/99 (6%)

Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
           + P+  L P ++ ++ G  A+F     G PEP + W   G      P  S  ++      
Sbjct: 31  EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQ-----PITSGGRFLLDCGI 85

Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389
            G   L I+   + D R    C A N +G+  V  +LTV
Sbjct: 86  RGTFSLVIHAVHEED-RGKYTCEATNGSGARQVTVELTV 123



 Score = 36.7 bits (81), Expect = 3.9
 Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 6/84 (7%)

Query: 110  FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV--- 166
            F+ + +    A+G  ++L+C      P   + W  NG+TL       + L   G+L    
Sbjct: 1100 FKQKLQDVHVAEGKKLLLQC-QVSSDPPATIIWTLNGKTL--KTTKFIILSQEGSLCSVS 1156

Query: 167  IQDARQTDAGRYQCIARNAAGTRE 190
            I+ A   D G Y+C+A+N AG  E
Sbjct: 1157 IEKALPEDRGLYKCVAKNDAGQAE 1180



 Score = 35.5 bits (78), Expect = 8.9
 Identities = 32/112 (28%), Positives = 43/112 (38%), Gaps = 3/112 (2%)

Query: 7    TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66
            + G AP   ++  DV VA  +   L C+    P   I W   G   +  T   IL   G 
Sbjct: 1093 SQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGS 1151

Query: 67   FFLRATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESK 117
                +    +  D G+Y C A N  G A  S   T+  A   E  +  PE K
Sbjct: 1152 LCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTK-APEMK 1202


>UniRef50_Q96JA1 Cluster: Leucine-rich repeats and
           immunoglobulin-like domains protein 1 precursor; n=22;
           Euteleostomi|Rep: Leucine-rich repeats and
           immunoglobulin-like domains protein 1 precursor - Homo
           sapiens (Human)
          Length = 1093

 Score =  111 bits (268), Expect = 8e-23
 Identities = 82/298 (27%), Positives = 132/298 (44%), Gaps = 24/298 (8%)

Query: 106 LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVY-WKKNGQTLL---FDGDSRMHLVD 161
           L+ +   +PE+  +  G  +   C     S  P  + WKK+ + L     +    +H  D
Sbjct: 493 LKPQIITQPETTMAMVGKDIRFTCSAASSSSSPMTFAWKKDNEVLTNADMENFVHVHAQD 552

Query: 162 GGNL---VIQDARQTD---AGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT 215
           G  +    I   RQ      GRYQC+  N  G+  S  A L +++ P     P D+  +T
Sbjct: 553 GEVMEYTTILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVNVLPSFTKTPHDITIRT 612

Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL----DDGSLRLDNVILADEGEYS 271
            +    +C   G P P + W++  GG + P  R + +    DD    + +V + D G YS
Sbjct: 613 TTMARLECAATGHPNPQIAWQKD-GGTDFPAARERRMHVMPDDDVFFITDVKIDDAGVYS 671

Query: 272 CEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGN 331
           C A+NS G++SA+  LTV + PS+ +      V  G      C ATG P P + W  +G+
Sbjct: 672 CTAQNSAGSISANATLTVLETPSLVVPLEDRVVSVGETVALQCKATGNPPPRITW-FKGD 730

Query: 332 RTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389
           R    P    +++H T   D   ++  N   ++  R T  C   N  G+     +L+V
Sbjct: 731 R----PLSLTERHHLTP--DNQLLVVQNVVAEDAGRYT--CEMSNTLGTERAHSQLSV 780



 Score = 94.3 bits (224), Expect = 2e-17
 Identities = 78/289 (26%), Positives = 111/289 (38%), Gaps = 25/289 (8%)

Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL--WRRS---AGGGNMPLGRVKVLDD 254
           +KP +IT PE  +A  G  + F C         +   W++        +M         D
Sbjct: 493 LKPQIITQPETTMAMVGKDIRFTCSAASSSSSPMTFAWKKDNEVLTNADMENFVHVHAQD 552

Query: 255 GS-------LRLDNVILADEGEYSCEAENSVGAV-SASGYLTVYDPPSINLSPNSVNVES 306
           G        L L  V    EG Y C   N  G+  S    LTV   PS   +P+ + + +
Sbjct: 553 GEVMEYTTILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVNVLPSFTKTPHDITIRT 612

Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
             +AR  C ATG P P + W  +G     FP     + H     D   V  I D  K D 
Sbjct: 613 TTMARLECAATGHPNPQIAWQKDGGTD--FPAARERRMHVMPDDD---VFFITDV-KIDD 666

Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
                C+A N AGS      LTV        P+      ++ + +       C A   P 
Sbjct: 667 AGVYSCTAQNSAGSISANATLTVLETPSLVVPL-----EDRVVSVGETVALQCKATGNPP 721

Query: 427 PIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
           P I W+     L    R ++T D   LV++++   D+G YTC  S+  G
Sbjct: 722 PRITWFKGDRPLSLTERHHLTPDNQLLVVQNVVAEDAGRYTCEMSNTLG 770



 Score = 89.4 bits (212), Expect = 5e-16
 Identities = 66/191 (34%), Positives = 90/191 (47%), Gaps = 14/191 (7%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG---VLVVSDTHRSILP 62
           +T    P   + P D+T+     A L C A G P+P I W K G        +    ++P
Sbjct: 593 LTVNVLPSFTKTPHDITIRTTTMARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMP 652

Query: 63  AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQ 121
              +FF+  T  ++  DAGVY C A NS G+  S NATL   VL     + P E +  + 
Sbjct: 653 DDDVFFI--TDVKI-DDAGVYSCTAQNSAGSI-SANATL--TVLETPSLVVPLEDRVVSV 706

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQC 180
           G+TV L+C    G+P P + W K  + L      R HL  D   LV+Q+    DAGRY C
Sbjct: 707 GETVALQC-KATGNPPPRITWFKGDRPLSL--TERHHLTPDNQLLVVQNVVAEDAGRYTC 763

Query: 181 IARNAAGTRES 191
              N  GT  +
Sbjct: 764 EMSNTLGTERA 774



 Score = 51.6 bits (118), Expect = 1e-04
 Identities = 49/202 (24%), Positives = 81/202 (40%), Gaps = 17/202 (8%)

Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA---- 348
           P I   P +     G   RFTC+A       M ++ + +  ++      +  H  A    
Sbjct: 495 PQIITQPETTMAMVGKDIRFTCSAASSSSSPMTFAWKKDNEVLTNADMENFVHVHAQDGE 554

Query: 349 VFDGVTVLTIND-TDKNDSRNTIVCSAVNYAGSSFV-RGKLTVTSDDDRPPPIITNGPSN 406
           V +  T+L +   T  ++ R    C   N+ GS++  + +LTV        P  T  P +
Sbjct: 555 VMEYTTILHLRQVTFGHEGRYQ--CVITNHFGSTYSHKARLTVNV-----LPSFTKTPHD 607

Query: 407 QTLPIKSMAVFPCTAICTPEPIIAWYFEG----EALIQNHRRNVTNDGTLVLKDLDKSDS 462
            T+   +MA   C A   P P IAW  +G     A  +     + +D    + D+   D+
Sbjct: 608 ITIRTTTMARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDDA 667

Query: 463 GTYTCVASSRHGKYVWSGALLV 484
           G Y+C A +  G    +  L V
Sbjct: 668 GVYSCTAQNSAGSISANATLTV 689



 Score = 48.8 bits (111), Expect = 9e-04
 Identities = 29/90 (32%), Positives = 46/90 (51%), Gaps = 5/90 (5%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLFF 68
           E P ++    D  V+  +   L C+A G+P P I W+KG   L +++ H  + P   L  
Sbjct: 691 ETPSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHH-LTPDNQLLV 749

Query: 69  LRATHGRVHSDAGVYWCEATNSYGTARSRN 98
           ++     V  DAG Y CE +N+ GT R+ +
Sbjct: 750 VQNV---VAEDAGRYTCEMSNTLGTERAHS 776


>UniRef50_Q4KMG0 Cluster: Cell adhesion
           molecule-related/down-regulated by oncogenes precursor;
           n=27; Tetrapoda|Rep: Cell adhesion
           molecule-related/down-regulated by oncogenes precursor -
           Homo sapiens (Human)
          Length = 1287

 Score =  111 bits (268), Expect = 8e-23
 Identities = 121/451 (26%), Positives = 174/451 (38%), Gaps = 31/451 (6%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
           V+S  APY   +PL        P  L+C A    +  I W   G  +  +     +  G 
Sbjct: 23  VSSDLAPYFTSEPLSAVQKLGGPVVLHCSAQ-PVTTRISWLHNGKTLDGNLEHIKIHQGT 81

Query: 66  LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
           L  L      +    G Y C A NS G   S  AT+ VAVL +          + +    
Sbjct: 82  LTILSLNSSLL----GYYQCLANNSIGAIVSGPATVSVAVLGDFGSSTKHVITAEEKSAG 137

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
            + C  P  +P+  V +K  G+ L    ++ + ++  GNL I +    D G Y+C A N 
Sbjct: 138 FIGCRVPESNPKAEVRYKIRGKWLEHSTENYL-ILPSGNLQILNVSLEDKGSYKCAAYNP 196

Query: 186 AG--TRESAIATLKIHIKP-----YLI--TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
                +   I    +  +P     +++  T  + +   + S VT +C V G P P V W 
Sbjct: 197 VTHQLKVEPIGRKLLVSRPSSDDVHILHPTHSQALAVLSRSPVTLECVVSGVPAPQVYWL 256

Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT-VYDPPSI 295
           +  G    P    + L    L  D+V  AD G YSC A N  G V    Y+  V +  SI
Sbjct: 257 KD-GQDIAPESNWRRLYS-HLATDSVDPADSGNYSCMAGNKSGDVKYVTYMVNVLEHASI 314

Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
           +       V  G    FTC   G P P   W    N   I P       H TA  +G+ +
Sbjct: 315 SKGLQDQIVSLGATVHFTCDVHGNPAPNCTWF--HNAQPIHPSAR----HLTAG-NGLKI 367

Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
             +   D    +    C A N  G     G+L + +D    P IIT  P +  +      
Sbjct: 368 SGVTVEDVGMYQ----CVADNGIGFMHSTGRLEIENDGGFKPVIIT-APVSAKVADGDFV 422

Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNV 446
              C A   P P+I WY +   LI +H   V
Sbjct: 423 TLSCNASGLPVPVIRWY-DSHGLITSHPSQV 452



 Score = 84.6 bits (200), Expect = 1e-14
 Identities = 99/390 (25%), Positives = 154/390 (39%), Gaps = 34/390 (8%)

Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
           F  EP S     G  VVL C     +    + W  NG+TL  DG+     +  G L I  
Sbjct: 31  FTSEPLSAVQKLGGPVVLHCSAQPVTTR--ISWLHNGKTL--DGNLEHIKIHQGTLTILS 86

Query: 170 ARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTF-QCRVG-G 227
              +  G YQC+A N+ G   S  AT+ + +     +  + V+     S  F  CRV   
Sbjct: 87  LNSSLLGYYQCLANNSIGAIVSGPATVSVAVLGDFGSSTKHVITAEEKSAGFIGCRVPES 146

Query: 228 DPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG---AVSAS 284
           +P  +V ++              +L  G+L++ NV L D+G Y C A N V     V   
Sbjct: 147 NPKAEVRYKIRGKWLEHSTENYLILPSGNLQILNVSLEDKGSYKCAAYNPVTHQLKVEPI 206

Query: 285 GYLTVYDPPSIN----LSP---NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337
           G   +   PS +    L P    ++ V S +     C  +G P P ++W  +G    I P
Sbjct: 207 GRKLLVSRPSSDDVHILHPTHSQALAVLSRSPVTLECVVSGVPAPQVYWLKDGQD--IAP 264

Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGS-SFVRGKLTVTSDDDRP 396
             +  + ++    D V        D  DS N   C A N +G   +V   + V       
Sbjct: 265 ESNWRRLYSHLATDSV--------DPADSGN-YSCMAGNKSGDVKYVTYMVNVLEHAS-- 313

Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKD 456
              I+ G  +Q + + +   F C     P P   W+   +  I    R++T    L +  
Sbjct: 314 ---ISKGLQDQIVSLGATVHFTCDVHGNPAPNCTWFHNAQP-IHPSARHLTAGNGLKISG 369

Query: 457 LDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
           +   D G Y CVA +  G    +G L +++
Sbjct: 370 VTVEDVGMYQCVADNGIGFMHSTGRLEIEN 399



 Score = 42.3 bits (95), Expect = 0.078
 Identities = 58/232 (25%), Positives = 93/232 (40%), Gaps = 32/232 (13%)

Query: 501 SSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGW 560
           S +P  P +P     ++TSV ++W      G S I  ++VE + R   S          W
Sbjct: 718 SGVPEAPDRPTISTASETSVYVTWIPRAN-GGSPITAFKVE-YKRMRTSN---------W 766

Query: 561 VVIARRV--HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGT 618
           +V A  +   +    V+SL PG TY F V   N +G S  S  S    V           
Sbjct: 767 LVAAEDIPPSKLSVEVRSLEPGSTYKFRVIAINHYGESFRSSASRPYQV----------V 816

Query: 619 GVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEIL----NFYYLEGLFIYFRPLDNI 674
           G  N   + +  +T   +   EA  +    I L W  +    N   ++G +IY+RP D+ 
Sbjct: 817 GFPN--RFSSRPITGPHIAYTEA--VSDTQIMLKWTYIPSSNNNTPIQGFYIYYRPTDSD 872

Query: 675 TIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQT 726
             + + K  +         I  L+  T Y+  +  F +  E + SN  + +T
Sbjct: 873 N-DSDYKRDVVEGSKQWHMIGHLQPETSYDIKMQCFNEGGESEFSNVMICET 923


>UniRef50_UPI0000546958 Cluster: PREDICTED: hypothetical protein;
           n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 1563

 Score =  111 bits (267), Expect = 1e-22
 Identities = 119/497 (23%), Positives = 201/497 (40%), Gaps = 58/497 (11%)

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
           G ++ L+C   +G+P P + W K+G  +      ++ +V+G       +R+  AG+YQC 
Sbjct: 151 GRSLTLKCAA-QGNPRPTITWSKDGAPI--KPQHKVKMVNGSVSFHAVSREA-AGQYQCY 206

Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV--LWRRSA 239
             N+ G   + +  LKI   P +I  P D V         +C+   DP P++  +W+R  
Sbjct: 207 TSNSEGNA-THVTRLKIIGPPVIIIPPSDTVLNMSQDAKLKCQAEADP-PNMTYVWQRQG 264

Query: 240 GGG---NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSI 295
                 +    R+KV+ DG+L +  +   D G Y+C   N +  + SAS  LTV  P  +
Sbjct: 265 VDIYHIDSLKSRIKVIVDGTLLISRLAPEDSGNYTCMPTNGLPVSPSASAVLTVQHPAQV 324

Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMF-WSVEGNRTII--FPGMSRDKYHATAVFDG 352
              P    + +G      C     P  +   W  +G    +  +PG        T   DG
Sbjct: 325 IQMPKLTFLPTGMRGAIVCPVRAEPPLSHIDWIKDGKPLDLGMYPGW-------TLASDG 377

Query: 353 -VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ-TLP 410
            + + T+ND    D+    +C+  N  G++      TV   D   PP     P N+    
Sbjct: 378 SIVIATVND----DAAGVYICTPYNSFGTTGQSEPTTVILQD---PPSFKVSPRNEYRQD 430

Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470
           + +M V PC  +  P P + W   G A        +  +G+L+L  L K   G + C +S
Sbjct: 431 VGTMLVIPCQMVGNPAPKVNWRKIGAA--TRSLFTLAGNGSLILHPLSKDHQGEWECSSS 488

Query: 471 SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530
           +R         +LV   +  + H    + VS +PG                +SW      
Sbjct: 489 NRVATVSIKTMVLV---LGTSPH--AVSSVSVIPG-----------TNQANVSWVAGFDG 532

Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590
           G +        V+ ++  +G    +    W+  +    +   +V +L+P   Y F V  +
Sbjct: 533 GYTQTF----TVWYKQVSAGRTEEKQE--WLSFSDLSTENSLLVTNLLPATEYQFSVMAQ 586

Query: 591 NSHGLSGPSPVSDSVTV 607
           N     G  P S+ +TV
Sbjct: 587 NK---IGTGPFSEIITV 600



 Score = 97.5 bits (232), Expect = 2e-18
 Identities = 90/332 (27%), Positives = 126/332 (37%), Gaps = 19/332 (5%)

Query: 12  PYIIE-QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
           P + E  P +V V   +  TL C A G+P P I W K G   +   H+  +  G + F  
Sbjct: 136 PVLTETSPPEVEVFVGRSLTLKCAAQGNPRPTITWSKDGA-PIKPQHKVKMVNGSVSF-- 192

Query: 71  ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
             H      AG Y C  +NS G A   + T    +      + P            L+C 
Sbjct: 193 --HAVSREAAGQYQCYTSNSEGNAT--HVTRLKIIGPPVIIIPPSDTVLNMSQDAKLKCQ 248

Query: 131 PPRGSPEPNVYWKKNGQTLL-FDG-DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
                P     W++ G  +   D   SR+ ++  G L+I      D+G Y C+  N    
Sbjct: 249 AEADPPNMTYVWQRQGVDIYHIDSLKSRIKVIVDGTLLISRLAPEDSGNYTCMPTNGLPV 308

Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD-PLPDVLWRRSAGGGNMPLG 247
             SA A L +     +I  P+     TG      C V  + PL  + W +   G  + LG
Sbjct: 309 SPSASAVLTVQHPAQVIQMPKLTFLPTGMRGAIVCPVRAEPPLSHIDWIKD--GKPLDLG 366

Query: 248 RV---KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV--YDPPSINLSP-NS 301
                 +  DGS+ +  V     G Y C   NS G    S   TV   DPPS  +SP N 
Sbjct: 367 MYPGWTLASDGSIVIATVNDDAAGVYICTPYNSFGTTGQSEPTTVILQDPPSFKVSPRNE 426

Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRT 333
              + G +    C   G P P + W   G  T
Sbjct: 427 YRQDVGTMLVIPCQMVGNPAPKVNWRKIGAAT 458



 Score = 76.6 bits (180), Expect = 4e-12
 Identities = 83/334 (24%), Positives = 127/334 (38%), Gaps = 24/334 (7%)

Query: 152 DGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT-----LKIHIKPYLI- 205
           D D R+ L  G +L +   +  D G Y+C       T E A ++     L +   P L  
Sbjct: 81  DYDGRVSLFGGTSLQMSGLQLEDEGWYECRILPLDQTTEEAGSSGSWTRLSVTAPPVLTE 140

Query: 206 TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA 265
           T P +V    G S+T +C   G+P P + W +  G    P  +VK++ +GS+    V   
Sbjct: 141 TSPPEVEVFVGRSLTLKCAAQGNPRPTITWSKD-GAPIKPQHKVKMV-NGSVSFHAVSRE 198

Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA-TGRPEPTM 324
             G+Y C   NS G  +    L +  PP I + P+   +     A+  C A    P  T 
Sbjct: 199 AAGQYQCYTSNSEGNATHVTRLKIIGPPVIIIPPSDTVLNMSQDAKLKCQAEADPPNMTY 258

Query: 325 FWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR 384
            W  +G   +    +   K     + DG   L I+     DS N           S    
Sbjct: 259 VWQRQG---VDIYHIDSLKSRIKVIVDG--TLLISRLAPEDSGNYTCMPTNGLPVSPSAS 313

Query: 385 GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI--IAWYFEGEALIQNH 442
             LTV     + P  +   P    LP        C     P P+  I W  +G+ L    
Sbjct: 314 AVLTV-----QHPAQVIQMPKLTFLPTGMRGAIVCPVRAEP-PLSHIDWIKDGKPLDLGM 367

Query: 443 RRNVT--NDGTLVLKDLDKSDSGTYTCVASSRHG 474
               T  +DG++V+  ++   +G Y C   +  G
Sbjct: 368 YPGWTLASDGSIVIATVNDDAAGVYICTPYNSFG 401



 Score = 61.7 bits (143), Expect = 1e-07
 Identities = 48/216 (22%), Positives = 87/216 (40%), Gaps = 10/216 (4%)

Query: 80  AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
           AGVY C   NS+GT      T  +      F++ P ++      T+++      G+P P 
Sbjct: 389 AGVYICTPYNSFGTTGQSEPTTVILQDPPSFKVSPRNEYRQDVGTMLVIPCQMVGNPAPK 448

Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
           V W+K G        S   L   G+L++    +   G ++C + N   T       L + 
Sbjct: 449 VNWRKIGAAT----RSLFTLAGNGSLILHPLSKDHQGEWECSSSNRVATVSIKTMVLVLG 504

Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLWRRSAGGGNMP-----LGRVKVLD 253
             P+ ++    +     ++V++     GG      +W +    G        L    +  
Sbjct: 505 TSPHAVSSVSVIPGTNQANVSWVAGFDGGYTQTFTVWYKQVSAGRTEEKQEWLSFSDLST 564

Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
           + SL + N++ A E ++S  A+N +G    S  +TV
Sbjct: 565 ENSLLVTNLLPATEYQFSVMAQNKIGTGPFSEIITV 600


>UniRef50_UPI0000DB7443 Cluster: PREDICTED: similar to Fasciclin 2
           CG3665-PB, isoform B isoform 1; n=1; Apis mellifera|Rep:
           PREDICTED: similar to Fasciclin 2 CG3665-PB, isoform B
           isoform 1 - Apis mellifera
          Length = 741

 Score =  111 bits (266), Expect = 1e-22
 Identities = 107/407 (26%), Positives = 172/407 (42%), Gaps = 23/407 (5%)

Query: 80  AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
           AG Y C+AT +      ++ T+   ++   +   P ++    G+   ++C   R  P P+
Sbjct: 89  AGKYTCKATYANSIQLQKSVTIDT-IVAITWDNAPLNQYPILGEDFAIQC-KVRARPSPS 146

Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN-AAGTRESAIATLKI 198
           V W  NG+ L+   D   +++D   L I++ +++D G Y C A   + G  +     +++
Sbjct: 147 VDWLYNGE-LIKTNDH--YIIDTYALKIKNVQESDDGVYTCRASVFSTGELKERPIRVEV 203

Query: 199 HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP-LGRVKV-LDDGS 256
           HI+P +   P  +    G   + +C   G P P   W +S    N+  + R  V  D G 
Sbjct: 204 HIRPTVSEMPNPINMIEGKDASIKCEARGKPPPKFTWVKSLTHQNLSNVDRFSVDPDTGV 263

Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316
           L + NV   D GEY C A N  G  + +  + V   P I    NS  VE    A   C A
Sbjct: 264 LTITNVNRDDAGEYQCTATNLAGTANTNIMVNVIVKPKIIEFLNSTVVEDKE-ATLVCKA 322

Query: 317 TGRPEPTM-FWSVEGNRTIIF-PGMSRDKYHA-TAVFDGVTVLTINDTDKNDSRNTIV-C 372
            GRP P + F  +   +  +  P +  D+     +  D  T+ T+  +    S + +  C
Sbjct: 323 FGRPPPQVTFRKLTAEKAYVKGPQLDDDRIILENSGDDSETIGTLTISQSLRSNDGLYEC 382

Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
            A N  G +   G LTV    + PP   +   ++     +      C A   P   I W 
Sbjct: 383 IAQNAGGDARRIGHLTV----EFPPSFASMSNTSVWSWDQKPVNISCIAESIPNATIRWT 438

Query: 433 FEGEALIQNHRRNVTNDGT-----LVLKDLDKSDSGTYTCVASSRHG 474
             G+  I N +  +T  G      L +  LDK    TY C+AS+ HG
Sbjct: 439 MYGDQKIDNDKM-ITQIGNGPRSILTIVPLDKRYYTTYKCIASNAHG 484



 Score =  104 bits (249), Expect = 2e-20
 Identities = 101/367 (27%), Positives = 158/367 (43%), Gaps = 33/367 (8%)

Query: 31  LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
           + C+    PSP++ W   G L+ ++ H  I      + L+  + +  SD GVY C A+  
Sbjct: 135 IQCKVRARPSPSVDWLYNGELIKTNDHYII----DTYALKIKNVQ-ESDDGVYTCRAS-V 188

Query: 91  YGTARSRNATLHVAV-LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
           + T   +   + V V +R      P      +G    ++C   RG P P   W K+    
Sbjct: 189 FSTGELKERPIRVEVHIRPTVSEMPNPINMIEGKDASIKC-EARGKPPPKFTWVKSLTHQ 247

Query: 150 LFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208
                 R  +  D G L I +  + DAG YQC A N AGT  + I  + + +KP +I   
Sbjct: 248 NLSNVDRFSVDPDTGVLTITNVNRDDAGEYQCTATNLAGTANTNI-MVNVIVKPKIIEFL 306

Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG------GGNMPLGRVKVL---DD----G 255
              V +     T  C+  G P P V +R+         G  +   R+ +    DD    G
Sbjct: 307 NSTVVE-DKEATLVCKAFGRPPPQVTFRKLTAEKAYVKGPQLDDDRIILENSGDDSETIG 365

Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-NLSPNSVNVESGNVARFTC 314
           +L +   + +++G Y C A+N+ G     G+LTV  PPS  ++S  SV          +C
Sbjct: 366 TLTISQSLRSNDGLYECIAQNAGGDARRIGHLTVEFPPSFASMSNTSVWSWDQKPVNISC 425

Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV-TVLTINDTDKNDSRNTIVCS 373
            A   P  T+ W++ G++ I       DK   T + +G  ++LTI   DK     T  C 
Sbjct: 426 IAESIPNATIRWTMYGDQKI-----DNDKM-ITQIGNGPRSILTIVPLDKR-YYTTYKCI 478

Query: 374 AVNYAGS 380
           A N  G+
Sbjct: 479 ASNAHGT 485



 Score = 79.8 bits (188), Expect = 4e-13
 Identities = 84/350 (24%), Positives = 144/350 (41%), Gaps = 33/350 (9%)

Query: 155 SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQ 214
           + +H  +  +L     ++  AG+Y C A  A   +     T+   +       P +    
Sbjct: 69  TELHQDNSLSLFFNSLQEQQAGKYTCKATYANSIQLQKSVTIDTIVAITWDNAPLNQYPI 128

Query: 215 TGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEA 274
            G     QC+V   P P V W  +  G  +      ++D  +L++ NV  +D+G Y+C A
Sbjct: 129 LGEDFAIQCKVRARPSPSVDWLYN--GELIKTNDHYIIDTYALKIKNVQESDDGVYTCRA 186

Query: 275 EN-SVGAVSASGY-LTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332
              S G +      + V+  P+++  PN +N+  G  A   C A G+P P   W     +
Sbjct: 187 SVFSTGELKERPIRVEVHIRPTVSEMPNPINMIEGKDASIKCEARGKPPPKFTWV----K 242

Query: 333 TIIFPGMSR-DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTS 391
           ++    +S  D++   +V     VLTI + +++D+     C+A N AG++     + V  
Sbjct: 243 SLTHQNLSNVDRF---SVDPDTGVLTITNVNRDDA-GEYQCTATNLAGTANTNIMVNVIV 298

Query: 392 DDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW--------YFEGEAL----- 438
                P II     N T+     A   C A   P P + +        Y +G  L     
Sbjct: 299 K----PKIIEF--LNSTVVEDKEATLVCKAFGRPPPQVTFRKLTAEKAYVKGPQLDDDRI 352

Query: 439 -IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
            ++N   +    GTL +    +S+ G Y C+A +  G     G L V+ P
Sbjct: 353 ILENSGDDSETIGTLTISQSLRSNDGLYECIAQNAGGDARRIGHLTVEFP 402



 Score = 56.0 bits (129), Expect = 6e-06
 Identities = 53/190 (27%), Positives = 83/190 (43%), Gaps = 21/190 (11%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHR-SILPAGGLFFL 69
           P + E P  + +   + A++ C A G P P   W K      +S+  R S+ P  G+  +
Sbjct: 207 PTVSEMPNPINMIEGKDASIKCEARGKPPPKFTWVKSLTHQNLSNVDRFSVDPDTGVLTI 266

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
              +     DAG Y C ATN  GTA   N  + V V+ +   +E  +    +     L C
Sbjct: 267 TNVN---RDDAGEYQCTATNLAGTA---NTNIMVNVIVKPKIIEFLNSTVVEDKEATLVC 320

Query: 130 LPPRGSPEPNVYWKK-NGQTLLFDG----DSRMHLVDGGN-------LVIQDARQTDAGR 177
               G P P V ++K   +     G    D R+ L + G+       L I  + +++ G 
Sbjct: 321 -KAFGRPPPQVTFRKLTAEKAYVKGPQLDDDRIILENSGDDSETIGTLTISQSLRSNDGL 379

Query: 178 YQCIARNAAG 187
           Y+CIA+NA G
Sbjct: 380 YECIAQNAGG 389



 Score = 49.6 bits (113), Expect = 5e-04
 Identities = 45/170 (26%), Positives = 68/170 (40%), Gaps = 14/170 (8%)

Query: 337 PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP 396
           PG S+   +     D    L  N   +  +     C A  YA S  ++  +T+   D   
Sbjct: 60  PGHSKPPMYTELHQDNSLSLFFNSLQEQQA-GKYTCKAT-YANSIQLQKSVTI---DTIV 114

Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKD 456
                N P NQ   +       C     P P + W + GE LI+ +   + +   L +K+
Sbjct: 115 AITWDNAPLNQYPILGEDFAIQCKVRARPSPSVDWLYNGE-LIKTNDHYIIDTYALKIKN 173

Query: 457 LDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGP 506
           + +SD G YTC AS      V+S   L + PI   +H      VS +P P
Sbjct: 174 VQESDDGVYTCRAS------VFSTGELKERPIRVEVHI--RPTVSEMPNP 215



 Score = 36.7 bits (81), Expect = 3.9
 Identities = 43/170 (25%), Positives = 73/170 (42%), Gaps = 18/170 (10%)

Query: 27  QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG----GLFFLRATHGRVHSDAGV 82
           +P  ++C A   P+  IRW   G   + D  + I   G     +  +     R ++    
Sbjct: 419 KPVNISCIAESIPNATIRWTMYGDQKI-DNDKMITQIGNGPRSILTIVPLDKRYYT---T 474

Query: 83  YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP---- 138
           Y C A+N++GT R RN  L  A    E      ++ +A   T+  + +PP   PE     
Sbjct: 475 YKCIASNAHGT-RQRNIELREATKPGEMLQAKMAEITA--TTIRFDLVPPSTHPEQPLRT 531

Query: 139 -NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
            NV +K++GQT +    ++   VD    V++  +      ++  ARN  G
Sbjct: 532 INVQYKEDGQTWI-QARNKTWSVD-SYYVLEGLKPQTMYEFRFAARNDVG 579


>UniRef50_Q8WR45 Cluster: Immunoglobulin domain-containing protein
           Y54G2A.25; n=4; Caenorhabditis elegans|Rep:
           Immunoglobulin domain-containing protein Y54G2A.25 -
           Caenorhabditis elegans
          Length = 1187

 Score =  111 bits (266), Expect = 1e-22
 Identities = 112/477 (23%), Positives = 194/477 (40%), Gaps = 53/477 (11%)

Query: 30  TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP----AGGLFFLRATHGRVHSDAGVYWC 85
           TL C A  + +    W K G   V D+   +      +G + F +  H    S  G Y C
Sbjct: 50  TLRCEADEN-TDRYSWLKDGEPFVIDSEDVLWEKESQSGSIVFTKP-HA---SHQGYYQC 104

Query: 86  EATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW--- 142
            A+N +GTA S    L +  L    + + +  +  +G+++ L C PPRG+P+P + W   
Sbjct: 105 FASNIFGTALSNKMHLRLGSLEHFPKRDVKLLRVKEGESLTLNCTPPRGTPDPKIVWLYR 164

Query: 143 KKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGR---YQCIARNAAGTRESAIAT-LK 197
             +  +++    SR   VD  G+L       +D      Y+C A +     E      ++
Sbjct: 165 SLDDSSVIETIRSRHITVDNEGHLHFSSVELSDGKATLVYECAATSPVLRGEYRSGDRIQ 224

Query: 198 IHIKPY---------LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
           + I+P          +   P +V  + G  +  QC  GG PLP + W  S   G +P  R
Sbjct: 225 LDIEPSQDKSHPVKKMSVSPSEVTVRAGGQLKLQCIFGGRPLPTIFW--SKIDGELPKSR 282

Query: 249 VKVL-----DDG-SLRLDNVILADEGEYSCEAENSVGAVSA---SGYLTVYDPPSINLSP 299
           +K L     D G SL ++NV   D G Y C   + V  V+    +     +DP      P
Sbjct: 283 IKDLTSHESDFGRSLIVENVHPDDAGAYECRGRHLVHTVNVRVMAAPFWEFDP------P 336

Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
             +++   +     C A G+P P + WS+ G        ++ D      + D   +L + 
Sbjct: 337 RDISLPEESTGELECLAGGQPTPIITWSMNGK---FLHELAEDS--RRVLLDHGRILRVR 391

Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419
           + + +       C+A N  G  F    + V +     P        +  + + S  V  C
Sbjct: 392 NLNHDLDTGVYQCNASNPLGYVFANAFVHVRA---HAPFFRMPAARHWKVVLHSTVVLDC 448

Query: 420 TAICTPEPIIAWYFEGEALIQ--NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
                PE ++ W    +  +Q    +  +  + T ++ D++ +D G Y C  S+++G
Sbjct: 449 DVDAAPEAMVRWVDADDRPLQVVEGKNKLFPNHTFMVYDVNSADEGLYYCNVSNKYG 505



 Score = 81.4 bits (192), Expect = 1e-13
 Identities = 89/326 (27%), Positives = 128/326 (39%), Gaps = 22/326 (6%)

Query: 18  PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
           P +VTV       L C  GG P P I W K    +     + +      F        VH
Sbjct: 244 PSEVTVRAGGQLKLQCIFGGRPLPTIFWSKIDGELPKSRIKDLTSHESDFGRSLIVENVH 303

Query: 78  -SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
             DAG Y C   +   T   R     +A    EF   P      +  T  LECL   G P
Sbjct: 304 PDDAGAYECRGRHLVHTVNVR----VMAAPFWEFD-PPRDISLPEESTGELECL-AGGQP 357

Query: 137 EPNVYWKKNGQTL-LFDGDSRMHLVDGGNLV-IQDA-RQTDAGRYQCIARNAAG-TRESA 192
            P + W  NG+ L     DSR  L+D G ++ +++     D G YQC A N  G    +A
Sbjct: 358 TPIITWSMNGKFLHELAEDSRRVLLDHGRILRVRNLNHDLDTGVYQCNASNPLGYVFANA 417

Query: 193 IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL----GR 248
              ++ H   + +           S+V   C V   P   V W       + PL    G+
Sbjct: 418 FVHVRAHAPFFRMPAARHWKVVLHSTVVLDCDVDAAPEAMVRW---VDADDRPLQVVEGK 474

Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP-SINL-SPNSVNVES 306
            K+  + +  + +V  ADEG Y C   N  G   A+  L V+ P   + + +P  + +E+
Sbjct: 475 NKLFPNHTFMVYDVNSADEGLYYCNVSNKYGINRATNRLQVFKPTYFVRIPTPKRLILEA 534

Query: 307 GNVARFTCTATGRPE-PTMF-WSVEG 330
           G  A   C A   P  P  + W++ G
Sbjct: 535 GETAEVFCEAVADPRLPIRYQWTING 560



 Score = 81.0 bits (191), Expect = 2e-13
 Identities = 74/286 (25%), Positives = 113/286 (39%), Gaps = 13/286 (4%)

Query: 16  EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL---VVSDTHRSILPAGGLFFLRAT 72
           + P D+++       L C AGG P+P I W   G     +  D+ R +L  G +  LR  
Sbjct: 334 DPPRDISLPEESTGELECLAGGQPTPIITWSMNGKFLHELAEDSRRVLLDHGRI--LRVR 391

Query: 73  HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTVVLECL 130
           +     D GVY C A+N  G   + NA +HV      FR+ P ++  +     TVVL+C 
Sbjct: 392 NLNHDLDTGVYQCNASNPLGYVFA-NAFVHVRAHAPFFRM-PAARHWKVVLHSTVVLDC- 448

Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
               +PE  V W       L   + +  L      ++ D    D G Y C   N  G   
Sbjct: 449 DVDAAPEAMVRWVDADDRPLQVVEGKNKLFPNHTFMVYDVNSADEGLYYCNVSNKYGINR 508

Query: 191 SAIATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
            A   L++    Y   I  P+ ++ + G +    C    DP   + ++ +  G  +   +
Sbjct: 509 -ATNRLQVFKPTYFVRIPTPKRLILEAGETAEVFCEAVADPRLPIRYQWTINGKVLTESQ 567

Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
              +    LR  +V     G   C A   V    AS  L V D P+
Sbjct: 568 YYEILPDRLRFRSVRGRHSGIIDCAAITDVDVKLASMQLIVKDVPA 613



 Score = 42.3 bits (95), Expect = 0.078
 Identities = 43/183 (23%), Positives = 73/183 (39%), Gaps = 15/183 (8%)

Query: 642  TPIDSKTIKLMWEILNFYYLEGLFIYFR----PLDNITIEYEMKTILHSNDVSGFEITSL 697
            T I+  TI   W  ++   + G F+ +       +N   +Y +K   +S       I S 
Sbjct: 831  TQINFTTINFTWNPVDANTVNGHFVGYEIEYWKAENTIRKYSIKIPANSTYKV---INSF 887

Query: 698  RKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPEL 757
               T Y   +    K+    PS+  V+  + + P G   N+ ++ + +T + L+W  P L
Sbjct: 888  HAVTNYSAHIRTRNKRLRSAPSDY-VSFAMPEGPPGKVHNLRVYSVGSTAILLQWDAP-L 945

Query: 758  QLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817
            Q  NG I GY     ++     K+       +H+    +         Y V + AET  G
Sbjct: 946  Q-PNGRIRGY-----FISFQNEKNETEETYVIHRQKHYLHEKSEPDTGYKVSVWAETRAG 999

Query: 818  LGP 820
             GP
Sbjct: 1000 EGP 1002


>UniRef50_A7SC07 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 862

 Score =  111 bits (266), Expect = 1e-22
 Identities = 84/272 (30%), Positives = 121/272 (44%), Gaps = 21/272 (7%)

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDN 261
           P  I  P  +      +  F C   G P P ++W +  G   M     K+L +G L L+N
Sbjct: 209 PNAIVSPALITINASDTAVFHCAASGVPKPVLIWSKVDGAPLME-SSYKMLGNGRLVLEN 267

Query: 262 VILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESG-NVARFTCTATGRP 320
             L D G Y C+A N +G  SA+  L V  PPS+++      V+ G NV    C  TG P
Sbjct: 268 TTLEDAGLYECKAINLLGESSATMRLVVTVPPSVSIDIGPTYVQEGDNVMLPKCHVTGFP 327

Query: 321 EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGS 380
            P + W+            S  +     V      L+I     NDS     CSA N+ GS
Sbjct: 328 LPEINWT-----------RSAGQLPRRRVMTSGGQLSILAARANDS-GDYFCSARNHIGS 375

Query: 381 SFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP-IIAWYFEGEALI 439
           +  R +L V +     P  I + P +    + S  + PC A  +P P +I W+  G+++ 
Sbjct: 376 TIARTQLVVFA----LPRFIISPPKSLKAEVGSDVILPCKAYGSPPPLVITWHRHGKSIP 431

Query: 440 QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
           Q   R+   DG L L D+  +DSG Y C A+S
Sbjct: 432 Q--ERSGVIDGVLRLIDVTTADSGVYVCTATS 461



 Score =  109 bits (262), Expect = 5e-22
 Identities = 82/269 (30%), Positives = 123/269 (45%), Gaps = 16/269 (5%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
           AP  I  P  +T+     A  +C A G P P + W K     + ++   +L  G L    
Sbjct: 208 APNAIVSPALITINASDTAVFHCAASGVPKPVLIWSKVDGAPLMESSYKMLGNGRLVLEN 267

Query: 71  ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV-LREEFRLEPESKQSAQGDTVVLEC 129
            T      DAG+Y C+A N  G +   +AT+ + V +     ++       +GD V+L  
Sbjct: 268 TTL----EDAGLYECKAINLLGES---SATMRLVVTVPPSVSIDIGPTYVQEGDNVMLPK 320

Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
               G P P + W ++   L      R  +  GG L I  AR  D+G Y C ARN  G+ 
Sbjct: 321 CHVTGFPLPEINWTRSAGQL----PRRRVMTSGGQLSILAARANDSGDYFCSARNHIGST 376

Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL-WRRSAGGGNMPLGR 248
            +    +   +  ++I+ P+ + A+ GS V   C+  G P P V+ W R   G ++P  R
Sbjct: 377 IARTQLVVFALPRFIISPPKSLKAEVGSDVILPCKAYGSPPPLVITWHRH--GKSIPQER 434

Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENS 277
             V+ DG LRL +V  AD G Y C A +S
Sbjct: 435 SGVI-DGVLRLIDVTTADSGVYVCTATSS 462



 Score = 45.6 bits (103), Expect = 0.008
 Identities = 33/111 (29%), Positives = 55/111 (49%), Gaps = 3/111 (2%)

Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-YFEGEALIQN 441
           VRG+     D    P  I + P+  T+     AVF C A   P+P++ W   +G  L+++
Sbjct: 195 VRGEKGAPGDTLSAPNAIVS-PALITINASDTAVFHCAASGVPKPVLIWSKVDGAPLMES 253

Query: 442 HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
             + + N G LVL++    D+G Y C A +  G+   +  L+V  P + +I
Sbjct: 254 SYKMLGN-GRLVLENTTLEDAGLYECKAINLLGESSATMRLVVTVPPSVSI 303


>UniRef50_Q8AXY6 Cluster: Muscle, skeletal receptor tyrosine protein
           kinase precursor; n=18; Gnathostomata|Rep: Muscle,
           skeletal receptor tyrosine protein kinase precursor -
           Gallus gallus (Chicken)
          Length = 947

 Score =  110 bits (265), Expect = 2e-22
 Identities = 73/231 (31%), Positives = 116/231 (50%), Gaps = 10/231 (4%)

Query: 7   TSGEAPYIIEQPLDVTVARHQPAT-LNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAG 64
           T  +AP+I   PL+   A  +      C     P P I W +  + + + DT  SI   G
Sbjct: 23  TLQKAPFI-STPLETVDALVEDVPKFVCVVESYPEPEITWTRNSIPIRLFDTRYSIQRNG 81

Query: 65  GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
            L  + +      SD GVY C A N  G A      L V  +R +    P + +  +G  
Sbjct: 82  QLLTILSVED---SDDGVYCCTADNGVGAAAQSCGALQVK-MRPKITRPPVNVEIIEGLK 137

Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
            VL C    G+P+P+V W K G+T++ + ++R+ ++D GNL I + ++ DAG+Y+C+A+N
Sbjct: 138 AVLPCTT-MGNPKPSVSWIK-GETVVKE-NARIAVLDSGNLRIHNVQREDAGQYRCVAKN 194

Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
           + G+  S  AT+ + +   ++  PE      GS VT +C   G P+P V W
Sbjct: 195 SLGSAYSKPATVVVEVFARILKAPESQNITFGSMVTLRCTAAGAPVPTVTW 245



 Score =  102 bits (244), Expect = 7e-20
 Identities = 64/198 (32%), Positives = 92/198 (46%), Gaps = 6/198 (3%)

Query: 136 PEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAI 193
           PEP + W +N   + LFD  +R  +   G L+ I     +D G Y C A N  G    + 
Sbjct: 55  PEPEITWTRNSIPIRLFD--TRYSIQRNGQLLTILSVEDSDDGVYCCTADNGVGAAAQSC 112

Query: 194 ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD 253
             L++ ++P +   P +V    G      C   G+P P V W +          R+ VLD
Sbjct: 113 GALQVKMRPKITRPPVNVEIIEGLKAVLPCTTMGNPKPSVSWIKGETVVKEN-ARIAVLD 171

Query: 254 DGSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSPNSVNVESGNVARF 312
            G+LR+ NV   D G+Y C A+NS+G A S    + V     I  +P S N+  G++   
Sbjct: 172 SGNLRIHNVQREDAGQYRCVAKNSLGSAYSKPATVVVEVFARILKAPESQNITFGSMVTL 231

Query: 313 TCTATGRPEPTMFWSVEG 330
            CTA G P PT+ W   G
Sbjct: 232 RCTAAGAPVPTVTWLENG 249



 Score = 89.4 bits (212), Expect = 5e-16
 Identities = 75/277 (27%), Positives = 120/277 (43%), Gaps = 17/277 (6%)

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLD 260
           P++ T  E V A       F C V   P P++ W R++    +   R  +  +G  L + 
Sbjct: 28  PFISTPLETVDALVEDVPKFVCVVESYPEPEITWTRNSIPIRLFDTRYSIQRNGQLLTIL 87

Query: 261 NVILADEGEYSCEAENSVGAVSAS-GYLTVYDPPSINLSPNSVNVESGNVARFTCTATGR 319
           +V  +D+G Y C A+N VGA + S G L V   P I   P +V +  G  A   CT  G 
Sbjct: 88  SVEDSDDGVYCCTADNGVGAAAQSCGALQVKMRPKITRPPVNVEIIEGLKAVLPCTTMGN 147

Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379
           P+P++ W ++G   +        +    AV D    L I++  + D+     C A N  G
Sbjct: 148 PKPSVSW-IKGETVV-------KENARIAVLDSGN-LRIHNVQREDA-GQYRCVAKNSLG 197

Query: 380 SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI 439
           S++ +    V     R    I   P +Q +   SM    CTA   P P + W   G+A+ 
Sbjct: 198 SAYSKPATVVVEVFAR----ILKAPESQNITFGSMVTLRCTAAGAPVPTVTWLENGKAVS 253

Query: 440 QNHRRNVTNDGTLVLK-DLDKSDSGTYTCVASSRHGK 475
                    D  +  +  +  +  G +TC+A+++H K
Sbjct: 254 AGSIAESVKDRVVDSRLQVYVTRPGLFTCLATNKHSK 290



 Score = 79.8 bits (188), Expect = 4e-13
 Identities = 47/138 (34%), Positives = 67/138 (48%), Gaps = 6/138 (4%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P I   P++V +     A L C   G+P P++ W KG  +V  +   ++L +G L     
Sbjct: 121 PKITRPPVNVEIIEGLKAVLPCTTMGNPKPSVSWIKGETVVKENARIAVLDSGNL----R 176

Query: 72  THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
            H     DAG Y C A NS G+A S+ AT+ V V     +  PES+    G  V L C  
Sbjct: 177 IHNVQREDAGQYRCVAKNSLGSAYSKPATVVVEVFARILKA-PESQNITFGSMVTLRCTA 235

Query: 132 PRGSPEPNVYWKKNGQTL 149
             G+P P V W +NG+ +
Sbjct: 236 A-GAPVPTVTWLENGKAV 252



 Score = 66.1 bits (154), Expect = 6e-09
 Identities = 62/257 (24%), Positives = 110/257 (42%), Gaps = 20/257 (7%)

Query: 288 TVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
           T+   P I+    +V+    +V +F C     PEP + W+    R  I   +   +Y   
Sbjct: 23  TLQKAPFISTPLETVDALVEDVPKFVCVVESYPEPEITWT----RNSIPIRLFDTRYSIQ 78

Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR-GKLTVTSDDDRPPPIITNGPSN 406
                +T+L++ D+D         C+A N  G++    G L V     +  P IT  P N
Sbjct: 79  RNGQLLTILSVEDSDDG----VYCCTADNGVGAAAQSCGALQV-----KMRPKITRPPVN 129

Query: 407 QTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI-QNHRRNVTNDGTLVLKDLDKSDSGTY 465
             +     AV PCT +  P+P ++W  +GE ++ +N R  V + G L + ++ + D+G Y
Sbjct: 130 VEIIEGLKAVLPCTTMGNPKPSVSW-IKGETVVKENARIAVLDSGNLRIHNVQREDAGQY 188

Query: 466 TCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSV-TLSW 524
            CVA +  G      A +V   +       +A +  ++       +        V T++W
Sbjct: 189 RCVAKNSLGSAYSKPATVV---VEVFARILKAPESQNITFGSMVTLRCTAAGAPVPTVTW 245

Query: 525 SQNNKIGSSSILGYQVE 541
            +N K  S+  +   V+
Sbjct: 246 LENGKAVSAGSIAESVK 262


>UniRef50_Q9I7U4-3 Cluster: Isoform B of Q9I7U4 ; n=6;
           Sophophora|Rep: Isoform B of Q9I7U4 - Drosophila
           melanogaster (Fruit fly)
          Length = 17903

 Score =  110 bits (264), Expect = 3e-22
 Identities = 117/420 (27%), Positives = 184/420 (43%), Gaps = 48/420 (11%)

Query: 119 SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGR 177
           S +GD  V EC    G+PEP V W K+G ++  + D +     G   LVI++    D+ R
Sbjct: 236 SREGDRFVFEC-EVTGTPEPAVEWFKDGISIQTNSDYKTTFDKGICRLVIEETFAADSAR 294

Query: 178 YQCIARNAAGTRESAIATLKIH--------IKPYLITGPEDVVAQTGSSVTFQCRVGGDP 229
           + C A N  GT ++  ATL +         + P ++   +   A  GSS  F C V G P
Sbjct: 295 FSCRASNLVGTCDTN-ATLSVRENAAEVQLVPPRILRFLQSGKATEGSSFQFACVVAGVP 353

Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYL 287
           LP V W ++    +     V   ++G  +L+ + V L D+  Y+C A N  G    S  L
Sbjct: 354 LPTVQWFKNDKCIDDSPDYVISYNNGEATLKFEEVFLEDDAVYTCSASNPAGIEHCSASL 413

Query: 288 TV--YDP---PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRD 342
            V   +P   PS  +  ++     G   +      G P P ++W   G      P   RD
Sbjct: 414 IVEPLEPTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWLHNGK-----PFQPRD 468

Query: 343 KYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF------VRGKL-TVTSDDDR 395
             +      G   L I     ND+  + V SA N AG ++      V+G+L   TSD + 
Sbjct: 469 SKYEY----GRVTLIIPQAYPNDA-GSYVLSAKNLAGEAYTSCNVIVKGRLPNETSDSEM 523

Query: 396 PPPIITNGPSNQTLPIKSMAVFP-------CTAICTPEPIIAWYFEGEALIQNHRRNVTN 448
              I    P+   LP+K +++F        C  +  PEP + WY     + ++    +  
Sbjct: 524 ASDIEPIKPAVH-LPLKDVSIFEGKPVRLDCVIVGQPEPEVIWYHNERPVKESADVQLLF 582

Query: 449 DG---TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRA-ADVSSLP 504
            G   +L+++++ + D+G Y  VA +  G+   S  L V +P+N      RA A+  SLP
Sbjct: 583 QGDRCSLIIQEVYQEDAGHYKVVAINSAGEASSSCELKV-TPLNQAEPATRAQAERQSLP 641



 Score = 96.7 bits (230), Expect = 3e-18
 Identities = 96/383 (25%), Positives = 160/383 (41%), Gaps = 45/383 (11%)

Query: 110   FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV--- 166
             F  +P+++   +   V+LEC      PEP++ W  NG+ +  +    + +V   ++    
Sbjct: 16059 FSKKPKAQYVDENTNVILECRLV-AVPEPDIVWTFNGEDIDEEEIKNVRIVTESDMHMYC 16117

Query: 167   ----IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK----PYLITGPEDVVAQTGSS 218
                 I   +++  G Y+ IA N  G     I TLK+       P ++    ++V + G S
Sbjct: 16118 SVVHISKVKKSQEGTYEVIATNREGEARLPI-TLKVRTTDKEAPQILEPLRNMVIREGES 16176

Query: 219   VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGEYSCEAENS 277
             V    ++ G+P P V W +       P+   K   D  +L L     +++GEY+ +A N 
Sbjct: 16177 VVLSTQIVGNPPPKVTWYKDG----KPVKNAKSDKDLHTLTLITPQKSEKGEYTVKAVNP 16232

Query: 278   VGAVSASGYLTVYDPPSINLSP-------NSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
             +G+V  +  LT+ +P   N  P          NV      R     +G P P + W    
Sbjct: 16233 LGSVETTANLTIEEPAGGNAEPPLFVERFEEQNVPQKGEIRLPAKVSGNPVPEVQWLF-- 16290

Query: 331   NRTIIFPGMSRDKYHATAVFDGVTV-LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389
             N T +FP     +     V+DG  + L I D +         C A N  G +    ++ V
Sbjct: 16291 NNTPLFPSERIQQ-----VYDGENIELIIKDANPETDSGDYKCIASNPIGKTSHGARVIV 16345

Query: 390   TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA--WYFEGEALIQNHRRNVT 447
               D+     +       +T+ I+   V   T  C    ++   W+F G+ L     R V 
Sbjct: 16346 EVDE-----VTFTKKLKKTITIEE--VQSLTLECETSHVVTTKWFFNGKELSGMDHRVVV 16398

Query: 448   NDGT---LVLKDLDKSDSGTYTC 467
              DG    LV+++ +  DSGTYTC
Sbjct: 16399 EDGKTHKLVIRNTNLRDSGTYTC 16421



 Score = 94.7 bits (225), Expect = 1e-17
 Identities = 102/356 (28%), Positives = 148/356 (41%), Gaps = 34/356 (9%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
            V   +AP   ++     V  ++ A       G P+P ++WY+    + +     I    G
Sbjct: 6024 VKPAKAPVFTKKIQPCRVFENEQAKFEVEFEGEPNPTVKWYRESFPIQNSPDLQIHTFSG 6083

Query: 66   LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR--LEPES-KQSAQG 122
               L      V  D+ V+ C A N  GTA+  +A L V   R   +  ++P S   + Q 
Sbjct: 6084 KSILIIRQVFVE-DSAVFSCVAENRGGTAKC-SANLVVEERRRAGKGGIQPPSFVTTIQS 6141

Query: 123  DTVVLECLPP-----RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAG 176
             TV    L        G+   +VYW KNG  +      +M   D  + L+I +    D+G
Sbjct: 6142 TTVATGQLARFDAKVTGTRPLDVYWLKNGMKIQPSIKFKMLEEDSVHTLLIIEPFAEDSG 6201

Query: 177  RYQCIARNAAG-TRESAIATLKIHIKPYLITGP---------EDVVAQT---GSSVTFQC 223
            RY+C+A NAAG  R      ++   KP   T P         E + +QT   GS V F+C
Sbjct: 6202 RYECVAVNAAGEARCDGDCIVQSPSKPEKPTTPGSEKAPHIVEQLKSQTVEEGSKVIFRC 6261

Query: 224  RVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGA 280
            RV G P P   W R       P    ++   G    L +      DEG Y C AEN +G+
Sbjct: 6262 RVDGKPTPTARWMRGENFVK-PSRYFQMSRQGEYYQLVISEAFPEDEGTYKCVAENKLGS 6320

Query: 281  VSASGYLTV-----YDPPSINLSPNSVNVESGNVARFTCTATGRPEPT-MFWSVEG 330
            +  S  L V      D P    +   V+V  G  A+F  T TG+ + T + W  EG
Sbjct: 6321 IQTSAQLKVRPIENLDAPPTITALKDVSVTEGMPAQFKTTVTGKVKATSVQWFREG 6376



 Score = 87.4 bits (207), Expect = 2e-15
 Identities = 105/435 (24%), Positives = 172/435 (39%), Gaps = 43/435 (9%)

Query: 14  IIEQPLDVTVARHQPA-TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRAT 72
           +  +PL   V+R        C   G+P PA+ W+K G+ + +++        G+  L   
Sbjct: 226 LFTRPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTFDKGICRL-VI 284

Query: 73  HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-------ESKQSAQGDTV 125
                +D+  + C A+N  GT  + NATL V     E +L P       +S ++ +G + 
Sbjct: 285 EETFAADSARFSCRASNLVGTCDT-NATLSVRENAAEVQLVPPRILRFLQSGKATEGSSF 343

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARN 184
              C+   G P P V W KN + +    D  +   +G   L  ++    D   Y C A N
Sbjct: 344 QFACVVA-GVPLPTVQWFKNDKCIDDSPDYVISYNNGEATLKFEEVFLEDDAVYTCSASN 402

Query: 185 AAGTRESAIATLKIHIKPYLITG---P-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
            AG    + + +   ++P  +     P  + +A+ G  +  +  VGG P P+V W  +  
Sbjct: 403 PAGIEHCSASLIVEPLEPTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWLHNGK 462

Query: 241 -----GGNMPLGRVKVL-------DDGSLRLDNVILADEGEYSCEA---ENSVGAVSASG 285
                      GRV ++       D GS  L    LA E   SC            S S 
Sbjct: 463 PFQPRDSKYEYGRVTLIIPQAYPNDAGSYVLSAKNLAGEAYTSCNVIVKGRLPNETSDSE 522

Query: 286 YLTVYDP--PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDK 343
             +  +P  P+++L    V++  G   R  C   G+PEP + W     R +      ++ 
Sbjct: 523 MASDIEPIKPAVHLPLKDVSIFEGKPVRLDCVIVGQPEPEVIW-YHNERPV------KES 575

Query: 344 YHATAVFDGVTV-LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN 402
                +F G    L I +  + D+ +  V  A+N AG +    +L VT  +   P     
Sbjct: 576 ADVQLLFQGDRCSLIIQEVYQEDAGHYKVV-AINSAGEASSSCELKVTPLNQAEPATRAQ 634

Query: 403 GPSNQTLPIKSMAVF 417
               Q+LP  S   F
Sbjct: 635 A-ERQSLPKDSQPKF 648



 Score = 84.6 bits (200), Expect = 1e-14
 Identities = 108/496 (21%), Positives = 185/496 (37%), Gaps = 42/496 (8%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P I E+         +P  L C+  G P P I+WY   +L+ +     I     +  L+ 
Sbjct: 8090 PRITEKLRPRQCVPEEPTVLECKVEGVPFPEIKWYFNDILLFASEKYEITVMEQVAKLKI 8149

Query: 72   THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
                  SD GVY CEA N  G A SR   + +    +  ++E   ++  +   V + C  
Sbjct: 8150 AK-VTPSDVGVYTCEAKNEAGVATSR-TNIILGKFTKPLKIEFIEEKQPERLKVTVTC-Q 8206

Query: 132  PRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQT--DAGRYQCIARNAAGT 188
              G P P V W +  + ++     +M   +  G++ ++    T  +A  Y   A+N  G 
Sbjct: 8207 VTGKPNPEVKWYRGIEEVIPSETVQMFYDEKTGDVALEVINPTPNEAVVYSVQAQNQFGR 8266

Query: 189  RESAIATL-------KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
                   L       +  +K   +T    VV  TG ++ F+ +  G P P+V W R+  G
Sbjct: 8267 AIGNANILSRVDEVPREILKAPTVTPLSAVVVPTGGTLFFEAKYDGLPRPEVKWMRN--G 8324

Query: 242  GNMPLGRVKVLD----DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD------ 291
              +      +++      ++++ N+     G+Y   A+N VG   +SG + V D      
Sbjct: 8325 REIIENEETIIETTETTTTIKVVNMTRKRTGKYEVWAKNKVGEAKSSGSVVVSDQKPDEQ 8384

Query: 292  --PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
              PP               VA         P  +  W V        P  S ++    + 
Sbjct: 8385 IKPPRFIQPLEPKYFGEHEVAIIEAIVESEPLSSFQWFVHNE-----PIKSSNEVRIVSQ 8439

Query: 350  FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409
             +  T+L  N   K        C A N  GS      + +   ++               
Sbjct: 8440 ANKSTLLIENFQSK--FVGPFTCRAENVGGSVTSTATVNLIPQEEAEEFESPRFVEELVQ 8497

Query: 410  PIKSM----AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND--GT--LVLKDLDKSD 461
            P++ M     +  C     P P + WY   E + +N    ++ D  G   L + ++   +
Sbjct: 8498 PVEVMDGEALLLTCQVTGKPTPKVEWYHNAEKITENKETTISQDLQGVCQLQITEVFPEN 8557

Query: 462  SGTYTCVASSRHGKYV 477
             G Y CVA+++ GK V
Sbjct: 8558 EGQYECVATNKIGKSV 8573



 Score = 84.2 bits (199), Expect = 2e-14
 Identities = 77/312 (24%), Positives = 126/312 (40%), Gaps = 30/312 (9%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            +AP I ++P    +     A    R G +P P + W+  G  +V+     I  + G+  L
Sbjct: 1978 QAPQISQKPRSSKLIEGSDAVFTARVGSNPKPRLTWFHNGQRLVASQKYEISYSSGVATL 2037

Query: 70   RATHGRVHSDAGVYWCEATNSYG------------TARSRNATLHVAVLREEF---RLEP 114
            R  +     D G Y   A N  G             A +      V V+ E+    +  P
Sbjct: 2038 RVKNATAR-DGGHYTLLAENLQGCVVSSAVLAVEPAAETAYEPKPVDVMAEQLEAGKALP 2096

Query: 115  ESKQSAQGDTVVLECLPPR------GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LV 166
             +   A GD  + E    R      G+P P V+W  NG+ +  D   ++ + + G+  L+
Sbjct: 2097 PAFVKAFGDREITEGRMTRFDCRVTGNPYPEVFWLINGRQVRDDASHKILVNESGSHSLM 2156

Query: 167  IQDARQTDAGRYQCIARNAAG--TRESAIATLKIH--IKPYLITGPEDVVAQTGSSVTFQ 222
            I +  + DAG  QC+ARN AG    E+ +  L+    + P  +     +  + G  +T  
Sbjct: 2157 ITNVTRLDAGAVQCLARNKAGEVAIEAQLNVLEKEQVVAPQFVQRFSTMTVREGEPITMS 2216

Query: 223  CRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS--LRLDNVILADEGEYSCEAENSVGA 280
                G P P + W++     +    R   +D G+  L +  V   D G Y C A+N  G+
Sbjct: 2217 ANAIGTPQPRITWQKDGVQISSTAERFVGIDGGATCLEIPRVTANDAGWYQCTAQNIAGS 2276

Query: 281  VSASGYLTVYDP 292
             +    L V  P
Sbjct: 2277 TANRARLYVEVP 2288



 Score = 79.0 bits (186), Expect = 7e-13
 Identities = 94/352 (26%), Positives = 132/352 (37%), Gaps = 47/352 (13%)

Query: 202  PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS----L 257
            P +   P       GS   F  RVG +P P + W  +  G  +   +   +   S    L
Sbjct: 1980 PQISQKPRSSKLIEGSDAVFTARVGSNPKPRLTWFHN--GQRLVASQKYEISYSSGVATL 2037

Query: 258  RLDNVILADEGEYSCEAENSVGAVSASGYL-------TVYDPPSIN-----------LSP 299
            R+ N    D G Y+  AEN  G V +S  L       T Y+P  ++           L P
Sbjct: 2038 RVKNATARDGGHYTLLAENLQGCVVSSAVLAVEPAAETAYEPKPVDVMAEQLEAGKALPP 2097

Query: 300  NSVN------VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD-G 352
              V       +  G + RF C  TG P P +FW + G +      +  D  H   V + G
Sbjct: 2098 AFVKAFGDREITEGRMTRFDCRVTGNPYPEVFWLINGRQ------VRDDASHKILVNESG 2151

Query: 353  VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
               L I +  + D+   + C A N AG   +  +L V   +    P      S  T+   
Sbjct: 2152 SHSLMITNVTRLDA-GAVQCLARNKAGEVAIEAQLNVLEKEQVVAPQFVQRFSTMTVREG 2210

Query: 413  SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVA 469
                    AI TP+P I W  +G  +     R V  DG    L +  +  +D+G Y C A
Sbjct: 2211 EPITMSANAIGTPQPRITWQKDGVQISSTAERFVGIDGGATCLEIPRVTANDAGWYQCTA 2270

Query: 470  SSRHGKYVWSGALLVDSP-INPNIHFFRAADVSSLPGPPTKPITHNVTDTSV 520
             +  G       L V+ P   PN    R     +LP  PTK I      TSV
Sbjct: 2271 QNIAGSTANRARLYVEVPREQPNYEQRRL----NLP-RPTKVIEPGARATSV 2317



 Score = 72.1 bits (169), Expect = 8e-11
 Identities = 92/335 (27%), Positives = 130/335 (38%), Gaps = 48/335 (14%)

Query: 221  FQCRVGGDPLPDVLW-RRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSV 278
            F+    G+P P V W R S    N P  ++      S L +  V + D   +SC AEN  
Sbjct: 6049 FEVEFEGEPNPTVKWYRESFPIQNSPDLQIHTFSGKSILIIRQVFVEDSAVFSCVAENRG 6108

Query: 279  GAVSASGYLTVYD----------PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328
            G    S  L V +          PPS   +  S  V +G +ARF    TG     ++W  
Sbjct: 6109 GTAKCSANLVVEERRRAGKGGIQPPSFVTTIQSTTVATGQLARFDAKVTGTRPLDVYWLK 6168

Query: 329  EGNR---TIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385
             G +   +I F  +  D  H        T+L I    ++  R    C AVN AG +   G
Sbjct: 6169 NGMKIQPSIKFKMLEEDSVH--------TLLIIEPFAEDSGRYE--CVAVNAAGEARCDG 6218

Query: 386  KLTVTSDD--DRPP-------PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436
               V S    ++P        P I     +QT+   S  +F C     P P   W   GE
Sbjct: 6219 DCIVQSPSKPEKPTTPGSEKAPHIVEQLKSQTVEEGSKVIFRCRVDGKPTPTARW-MRGE 6277

Query: 437  ALIQNHRR-NVTNDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV------DS 486
              ++  R   ++  G    LV+ +    D GTY CVA ++ G    S  L V      D+
Sbjct: 6278 NFVKPSRYFQMSRQGEYYQLVISEAFPEDEGTYKCVAENKLGSIQTSAQLKVRPIENLDA 6337

Query: 487  PINPNIHFFRAADVS-SLPGPPTKPITHNVTDTSV 520
            P  P I   +   V+  +P      +T  V  TSV
Sbjct: 6338 P--PTITALKDVSVTEGMPAQFKTTVTGKVKATSV 6370



 Score = 70.1 bits (164), Expect = 3e-10
 Identities = 74/338 (21%), Positives = 131/338 (38%), Gaps = 30/338 (8%)

Query: 166   VIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV 225
             +I ++  +D G         + +RES++A +   I P     P+       ++V  +CR+
Sbjct: 16021 LIVESPLSDHGSDATALSRRSMSRESSLADILEGIPPTFSKKPKAQYVDENTNVILECRL 16080

Query: 226   GGDPLPDVLWRRSAGG-GNMPLGRVKVLDDGSL-------RLDNVILADEGEYSCEAENS 277
                P PD++W  +        +  V+++ +  +        +  V  + EG Y   A N 
Sbjct: 16081 VAVPEPDIVWTFNGEDIDEEEIKNVRIVTESDMHMYCSVVHISKVKKSQEGTYEVIATNR 16140

Query: 278   VG----AVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRT 333
              G     ++     T  + P I     ++ +  G     +    G P P + W  +G   
Sbjct: 16141 EGEARLPITLKVRTTDKEAPQILEPLRNMVIREGESVVLSTQIVGNPPPKVTWYKDGKPV 16200

Query: 334   IIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV--TS 391
                     DK   T     +T++T   ++K +        AVN  GS      LT+   +
Sbjct: 16201 ---KNAKSDKDLHT-----LTLITPQKSEKGE----YTVKAVNPLGSVETTANLTIEEPA 16248

Query: 392   DDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG- 450
               +  PP+       Q +P K     P      P P + W F    L  + R     DG 
Sbjct: 16249 GGNAEPPLFVERFEEQNVPQKGEIRLPAKVSGNPVPEVQWLFNNTPLFPSERIQQVYDGE 16308

Query: 451   --TLVLKDLD-KSDSGTYTCVASSRHGKYVWSGALLVD 485
                L++KD + ++DSG Y C+AS+  GK      ++V+
Sbjct: 16309 NIELIIKDANPETDSGDYKCIASNPIGKTSHGARVIVE 16346



 Score = 66.9 bits (156), Expect = 3e-09
 Identities = 77/322 (23%), Positives = 114/322 (35%), Gaps = 24/322 (7%)

Query: 204 LITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL--D 260
           L T P +D V++ G    F+C V G P P V W +               D G  RL  +
Sbjct: 226 LFTRPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTFDKGICRLVIE 285

Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVYD--------PPSINLSPNSVNVESGNVARF 312
               AD   +SC A N VG    +  L+V +        PP I     S     G+  +F
Sbjct: 286 ETFAADSARFSCRASNLVGTCDTNATLSVRENAAEVQLVPPRILRFLQSGKATEGSSFQF 345

Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
            C   G P PT+ W  + ++ I     S D  +  +  +G   L   +    D      C
Sbjct: 346 ACVVAGVPLPTVQW-FKNDKCI---DDSPD--YVISYNNGEATLKFEEVFLEDDA-VYTC 398

Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
           SA N AG       L V   +    P      SN    +             P P + W 
Sbjct: 399 SASNPAGIEHCSASLIVEPLEPTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWL 458

Query: 433 FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPI-NPN 491
             G+       +      TL++     +D+G+Y   A +  G+   S  ++V   + N  
Sbjct: 459 HNGKPFQPRDSKYEYGRVTLIIPQAYPNDAGSYVLSAKNLAGEAYTSCNVIVKGRLPNET 518

Query: 492 IHFFRAADVSSLPGPPTKPITH 513
                A+D+      P KP  H
Sbjct: 519 SDSEMASDIE-----PIKPAVH 535



 Score = 66.1 bits (154), Expect = 6e-09
 Identities = 122/490 (24%), Positives = 183/490 (37%), Gaps = 57/490 (11%)

Query: 6     VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD---THRSILP 62
             +  G  P   ++P    V  +    L CR    P P I W   G  +  +     R +  
Sbjct: 16051 ILEGIPPTFSKKPKAQYVDENTNVILECRLVAVPEPDIVWTFNGEDIDEEEIKNVRIVTE 16110

Query: 63    AGGLFFLRATH-GRVH-SDAGVYWCEATNSYGTARSRNATLHVAVLREEFR--LEP-ESK 117
             +    +    H  +V  S  G Y   ATN  G AR    TL V    +E    LEP  + 
Sbjct: 16111 SDMHMYCSVVHISKVKKSQEGTYEVIATNREGEARLP-ITLKVRTTDKEAPQILEPLRNM 16169

Query: 118   QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL-FDGDSRMHLVDGGNLVIQDARQTDAG 176
                +G++VVL      G+P P V W K+G+ +     D  +H      L +   ++++ G
Sbjct: 16170 VIREGESVVLSTQIV-GNPPPKVTWYKDGKPVKNAKSDKDLH-----TLTLITPQKSEKG 16223

Query: 177   RYQCIARNAAGTRESAIATLKI------HIKPYLITG--PEDVVAQTGSSVTFQCRVGGD 228
              Y   A N  G+ E+  A L I      + +P L      E  V Q G  +    +V G+
Sbjct: 16224 EYTVKAVNPLGSVETT-ANLTIEEPAGGNAEPPLFVERFEEQNVPQKGE-IRLPAKVSGN 16281

Query: 229   PLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL-----ADEGEYSCEAENSVGAVSA 283
             P+P+V W  +      P  R++ + DG   ++ +I       D G+Y C A N +G  S 
Sbjct: 16282 PVPEVQWLFN-NTPLFPSERIQQVYDGE-NIELIIKDANPETDSGDYKCIASNPIGKTS- 16338

Query: 284   SGYLTVYDPPSINLSPN-SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRD 342
              G   + +   +  +      +    V   T         T  W   G       GM   
Sbjct: 16339 HGARVIVEVDEVTFTKKLKKTITIEEVQSLTLECETSHVVTTKWFFNGKE---LSGMD-- 16393

Query: 343   KYHATAVFDGVT-VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401
               H   V DG T  L I +T+  DS  T  C        S V           R P  I 
Sbjct: 16394 --HRVVVEDGKTHKLVIRNTNLRDS-GTYTCKVKKQETQSTVEVL-------QRKPDFI- 16442

Query: 402   NGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI-QNHRRNVTNDGT---LVLKDL 457
                 +  +  K  A+     + T    + WY +GE +  +N       DG    LV++D+
Sbjct: 16443 KVLEDYEVTEKDTAILD-VELTTEATEVTWYKDGEKITPENKNVEFIKDGKARRLVIRDV 16501

Query: 458   DKSDSGTYTC 467
                D G YTC
Sbjct: 16502 TIHDEGQYTC 16511



 Score = 62.1 bits (144), Expect = 9e-08
 Identities = 48/159 (30%), Positives = 74/159 (46%), Gaps = 6/159 (3%)

Query: 37   GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
            G PSP I+  K G  +  D H  I        +      V  DAG Y   A+N+ G + S
Sbjct: 1002 GFPSPEIKVEKNGGQLFEDAHTRISNKCNRVTIELKQVGV-GDAGRYAVTASNTVGQSTS 1060

Query: 97   R-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155
              +  +   +    F    +++ S +G+ + +E +   G PEP V W K+ + L   G S
Sbjct: 1061 TADLVVKKTIFPPVFGRRLQAQVSKKGEKLTME-VEVTGLPEPTVTWLKDDKPLKDAGIS 1119

Query: 156  RMHLVDGGN---LVIQDARQTDAGRYQCIARNAAGTRES 191
               L+  GN   L+I+ A+ TD+G+Y   A NA G  +S
Sbjct: 1120 EHRLLAQGNSYRLIIEKAQTTDSGKYMVRATNAGGEAKS 1158



 Score = 60.9 bits (141), Expect = 2e-07
 Identities = 106/473 (22%), Positives = 178/473 (37%), Gaps = 38/473 (8%)

Query: 8     SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPAGGL 66
             + E P  +E+  +  V +     L  +  G+P P ++W +    L  S+  + +   G  
Sbjct: 16251 NAEPPLFVERFEEQNVPQKGEIRLPAKVSGNPVPEVQWLFNNTPLFPSERIQQVYD-GEN 16309

Query: 67    FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
               L        +D+G Y C A+N  G   S  A + V V  +E     + K++   + V 
Sbjct: 16310 IELIIKDANPETDSGDYKCIASNPIGKT-SHGARVIVEV--DEVTFTKKLKKTITIEEVQ 16366

Query: 127   LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIARN 184
                L    S      W  NG+  L   D R+ + DG    LVI++    D+G Y C  + 
Sbjct: 16367 SLTLECETSHVVTTKWFFNGKE-LSGMDHRVVVEDGKTHKLVIRNTNLRDSGTYTCKVKK 16425

Query: 185   AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
                 +E+      +  KP  I   ED       +      +  +   +V W +       
Sbjct: 16426 ----QETQSTVEVLQRKPDFIKVLEDYEVTEKDTAILDVELTTE-ATEVTWYKDGEKITP 16480

Query: 245   PLGRVKVLDDGSLR---LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
                 V+ + DG  R   + +V + DEG+Y+C+ E   G   +   + +  PP I    N 
Sbjct: 16481 ENKNVEFIKDGKARRLVIRDVTIHDEGQYTCKIE---GQECSCELVVIELPPEIVEPLND 16537

Query: 302   VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
             V V  G  A F      + +  + W   G + I+F     ++    A+      L I   
Sbjct: 16538 VAVTKGENAVFE-VELSKGDALVKWFKNG-KEIVF-----NERIQLAIDGKKQSLRIVKA 16590

Query: 362   DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
                D     V       G    + KLTV    + P         + TL  K+        
Sbjct: 16591 KPEDVGEYSV-----QVGEQTSKAKLTV----EEPLVDFVIRLPDITLATKTTDAEFTVQ 16641

Query: 422   ICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASS 471
             +  P+  + W  +G+ +  N +  V  +GT   LV+ D    D+G  +CVA +
Sbjct: 16642 LSQPDVEVTWCKKGKPIKPNQKHEVFVEGTVRRLVIHDASDEDAGEISCVAEN 16694



 Score = 56.4 bits (130), Expect = 4e-06
 Identities = 35/99 (35%), Positives = 50/99 (50%), Gaps = 2/99 (2%)

Query: 11   APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
            AP  +++   +TV   +P T++  A G+P P I W K GV + S   R +   GG   L 
Sbjct: 2195 APQFVQRFSTMTVREGEPITMSANAIGTPQPRITWQKDGVQISSTAERFVGIDGGATCLE 2254

Query: 71   ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE 109
                   +DAG Y C A N  G+  +R A L+V V RE+
Sbjct: 2255 IPRVTA-NDAGWYQCTAQNIAGSTANR-ARLYVEVPREQ 2291



 Score = 54.0 bits (124), Expect = 2e-05
 Identities = 55/228 (24%), Positives = 91/228 (39%), Gaps = 16/228 (7%)

Query: 12    PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
             P I+E   DV V + + A          +  ++W+K G  +V +    +   G    LR 
Sbjct: 16529 PEIVEPLNDVAVTKGENAVFEVELSKGDA-LVKWFKNGKEIVFNERIQLAIDGKKQSLRI 16587

Query: 72    THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
                +   D G Y  +       A+    T+   ++    RL P+   + +  T   E   
Sbjct: 16588 VKAKPE-DVGEYSVQVGEQTSKAK---LTVEEPLVDFVIRL-PDITLATK--TTDAEFTV 16640

Query: 132   PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGTR 189
                 P+  V W K G+ +  +    +  V+G    LVI DA   DAG   C+A N   + 
Sbjct: 16641 QLSQPDVEVTWCKKGKPIKPNQKHEV-FVEGTVRRLVIHDASDEDAGEISCVAENVTSST 16699

Query: 190   ESAIATLKIHIKPYLITGPED--VVAQTGSSVTFQCRVGGDPLPDVLW 235
             +  +  LK+   P +IT  +D  +  +    VTF  +  G P P+  W
Sbjct: 16700 KLCVEELKL---PPVITSDKDQTIKVKENDDVTFTVKYTGVPTPEACW 16744



 Score = 54.0 bits (124), Expect = 2e-05
 Identities = 43/196 (21%), Positives = 81/196 (41%), Gaps = 14/196 (7%)

Query: 205   ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD--GSLRLDNV 262
             +T  +DVV++    VT  C  GG P P V W+++   G +   R    ++      ++  
Sbjct: 16768 LTIKKDVVSELDKEVTLSCVFGGIPEPKVTWKKN---GQVFESRSIRYENRVAKYTIEKT 16824

Query: 263   ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN--SVNVESGNVARFTCTATGRP 320
              +  E  Y+C A N  G+   S  L +   P + +     +  + +G++     T  G P
Sbjct: 16825 TIETEATYTCVATNEKGSAETSCRLKLQQKPVLEVEDKYLTQKLRTGSILTIPATVRGYP 16884

Query: 321   EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGS 380
             +PT+ W  E         ++ +    T+ +      T+    +  S    V +A N +G+
Sbjct: 16885 QPTVTWHKETIEQKTTKSVTIETTETTSTY------TVKKVTREQSGKYKV-TATNESGT 16937

Query: 381   SFVRGKLTVTSDDDRP 396
             ++V   + V     RP
Sbjct: 16938 TYVECTVQVIDKPSRP 16953



 Score = 50.0 bits (114), Expect = 4e-04
 Identities = 77/311 (24%), Positives = 130/311 (41%), Gaps = 35/311 (11%)

Query: 43    IRWYKGGVLVVSDTHR-SILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATL 101
             + WYK G  +  +      +  G    L      +H D G Y C+        +  +  L
Sbjct: 16469 VTWYKDGEKITPENKNVEFIKDGKARRLVIRDVTIH-DEGQYTCKIEG-----QECSCEL 16522

Query: 102   HVAVLREEFRLEPESKQSA-QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL- 159
              V  L  E  +EP +  +  +G+  V E    +G  +  V W KNG+ ++F+   R+ L 
Sbjct: 16523 VVIELPPEI-VEPLNDVAVTKGENAVFEVELSKG--DALVKWFKNGKEIVFN--ERIQLA 16577

Query: 160   VDGG--NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGS 217
             +DG   +L I  A+  D G Y             A  T++  +  ++I  P+  +A   +
Sbjct: 16578 IDGKKQSLRIVKAKPEDVGEYSV---QVGEQTSKAKLTVEEPLVDFVIRLPDITLATKTT 16634

Query: 218   SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLR---LDNVILADEGEYSCEA 274
                F  ++   P  +V W +  G    P  + +V  +G++R   + +    D GE SC A
Sbjct: 16635 DAEFTVQLS-QPDVEVTWCKK-GKPIKPNQKHEVFVEGTVRRLVIHDASDEDAGEISCVA 16692

Query: 275   ENSVGAVSASGYLTVYD---PPSINLSPN-SVNVESGNVARFTCTATGRPEPTMFWSVEG 330
             EN    V++S  L V +   PP I    + ++ V+  +   FT   TG P P   W+   
Sbjct: 16693 EN----VTSSTKLCVEELKLPPVITSDKDQTIKVKENDDVTFTVKYTGVPTPEACWT--- 16745

Query: 331   NRTIIFPGMSR 341
              R ++ P   R
Sbjct: 16746 TRKVVIPKSKR 16756



 Score = 48.4 bits (110), Expect = 0.001
 Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 5/101 (4%)

Query: 389  VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA--ICTPEPIIAWYFEGEALIQNHRRNV 446
            V  DD   PP     P +  +   ++A F C    I  P   + W+  G+AL    R   
Sbjct: 5166 VPDDDTGKPPEFITSPFDMVIGENALAHFECRLQPINDPSMRVDWFHNGKALWAGSRIKT 5225

Query: 447  TNDGTLVLKDLD---KSDSGTYTCVASSRHGKYVWSGALLV 484
             ND   V+ ++    + DSG YTC A+++HG+   S  L V
Sbjct: 5226 INDFGFVILEIAGCYQRDSGLYTCKATNKHGEATVSCKLQV 5266



 Score = 45.2 bits (102), Expect = 0.011
 Identities = 31/92 (33%), Positives = 49/92 (53%), Gaps = 10/92 (10%)

Query: 111  RLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQ 168
            +LEP++ +  +GD     C+   G P P V W  NG T++    SR  L + G  +L + 
Sbjct: 5733 KLEPQTVE--EGDPARF-CVRVTGHPRPRVMWLINGHTVVH--GSRYKLTNDGMFHLDVP 5787

Query: 169  DARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
              RQ D G+ + IARN+ G    +IAT ++ +
Sbjct: 5788 KTRQYDTGKVEVIARNSVG---ESIATTELKV 5816



 Score = 45.2 bits (102), Expect = 0.011
 Identities = 44/173 (25%), Positives = 72/173 (41%), Gaps = 12/173 (6%)

Query: 20    DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
             DV     +  TL+C  GG P P + W K G +  S   RSI     +         + ++
Sbjct: 16773 DVVSELDKEVTLSCVFGGIPEPKVTWKKNGQVFES---RSIRYENRVAKYTIEKTTIETE 16829

Query: 80    AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK---QSAQGDTVVLECLPPRGSP 136
             A  Y C ATN  G+A + +  L    L+++  LE E K   Q  +  +++      RG P
Sbjct: 16830 A-TYTCVATNEKGSAET-SCRLK---LQQKPVLEVEDKYLTQKLRTGSILTIPATVRGYP 16884

Query: 137   EPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGT 188
             +P V W K            +   +      ++   +  +G+Y+  A N +GT
Sbjct: 16885 QPTVTWHKETIEQKTTKSVTIETTETTSTYTVKKVTREQSGKYKVTATNESGT 16937



 Score = 44.8 bits (101), Expect = 0.015
 Identities = 27/107 (25%), Positives = 48/107 (44%), Gaps = 6/107 (5%)

Query: 379  GSSFVRGKLT-VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437
            G ++V   LT V +  D  PP+      N        A+F       P+P + W  +G  
Sbjct: 1792 GGAYVPPSLTHVYAQGDISPPVFEQIFKNARFAQGGNALFEGRLRGNPKPFVTWTRKGAP 1851

Query: 438  LIQNHR-----RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479
            L+++ +        T D +L++  +   D G YTC A +++G+ + S
Sbjct: 1852 LLESQKFRMSYNEATGDVSLLINQIGPGDEGEYTCTARNQYGEAICS 1898



 Score = 44.8 bits (101), Expect = 0.015
 Identities = 49/160 (30%), Positives = 64/160 (40%), Gaps = 13/160 (8%)

Query: 37   GSPSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTAR 95
            G  S  I W Y G VL  S   R+I  A G   L     ++  D G Y C ATN +GTA 
Sbjct: 4693 GDQSMVIEWFYNGKVLEASHRVRTIY-AFGTVALEVLGTKIE-DTGTYTCRATNKHGTAE 4750

Query: 96   -SRNATLHVAVLREEFRLEPESKQ---SAQGDTVVLEC-LPPRGSPEPNVYWKKNGQTLL 150
             S N         ++ R     +       G +   EC L P   P+  V W  NG+  L
Sbjct: 4751 ISCNLECVDKPRGQKPRFTSHIQPLEGLKDGQSAHFECTLIPVNDPDLKVEWYHNGK--L 4808

Query: 151  FDGDSRMHLVDGGNLVIQD---ARQTDAGRYQCIARNAAG 187
                +R+  V     V+ D    +  D+G Y C A N  G
Sbjct: 4809 MRHSNRIKTVSDFGYVVLDISYLQDHDSGEYVCRAWNKYG 4848



 Score = 44.0 bits (99), Expect = 0.025
 Identities = 34/113 (30%), Positives = 51/113 (45%), Gaps = 12/113 (10%)

Query: 428  IIAWYFEGEALIQNHR-RNVTNDGTLVLKDLDKS--DSGTYTCVASSRHGKYVWSGAL-L 483
            +I W++ G+ L  +HR R +   GT+ L+ L     D+GTYTC A+++HG    S  L  
Sbjct: 4698 VIEWFYNGKVLEASHRVRTIYAFGTVALEVLGTKIEDTGTYTCRATNKHGTAEISCNLEC 4757

Query: 484  VDSPINPNIHFFRAADVSSLPGPPTKPITH------NVTDTSVTLSWSQNNKI 530
            VD P      F   + +  L G       H       V D  + + W  N K+
Sbjct: 4758 VDKPRGQKPRF--TSHIQPLEGLKDGQSAHFECTLIPVNDPDLKVEWYHNGKL 4808



 Score = 43.2 bits (97), Expect = 0.044
 Identities = 26/88 (29%), Positives = 37/88 (42%), Gaps = 4/88 (4%)

Query: 216  GSSVTFQCRVGGDPLPDVLWRRSAG----GGNMPLGRVKVLDDGSLRLDNVILADEGEYS 271
            G +  F+ R+ G+P P V W R            +   +   D SL ++ +   DEGEY+
Sbjct: 1826 GGNALFEGRLRGNPKPFVTWTRKGAPLLESQKFRMSYNEATGDVSLLINQIGPGDEGEYT 1885

Query: 272  CEAENSVGAVSASGYLTVYDPPSINLSP 299
            C A N  G    S Y+     P   L P
Sbjct: 1886 CTARNQYGEAICSVYIQPEGAPMPALQP 1913



 Score = 43.2 bits (97), Expect = 0.044
 Identities = 24/89 (26%), Positives = 39/89 (43%), Gaps = 3/89 (3%)

Query: 8    SGEAPYIIEQPLDVTVARHQPATLNCRAG--GSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
            +G+ P  I  P D+ +  +  A   CR      PS  + W+  G  + + +    +   G
Sbjct: 5171 TGKPPEFITSPFDMVIGENALAHFECRLQPINDPSMRVDWFHNGKALWAGSRIKTINDFG 5230

Query: 66   LFFLRATHGRVHSDAGVYWCEATNSYGTA 94
               L    G    D+G+Y C+ATN +G A
Sbjct: 5231 FVILEIA-GCYQRDSGLYTCKATNKHGEA 5258



 Score = 42.7 bits (96), Expect = 0.059
 Identities = 46/184 (25%), Positives = 73/184 (39%), Gaps = 21/184 (11%)

Query: 313   TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
             +C   G PEP + W   G    +F   S  +Y      + V   TI  T   ++  T  C
Sbjct: 16785 SCVFGGIPEPKVTWKKNGQ---VFESRSI-RYE-----NRVAKYTIEKTTI-ETEATYTC 16834

Query: 373   SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
              A N  GS+    +L +     +P   + +    Q L   S+   P T    P+P + W+
Sbjct: 16835 VATNEKGSAETSCRLKL---QQKPVLEVEDKYLTQKLRTGSILTIPATVRGYPQPTVTWH 16891

Query: 433   FEGEALIQNHRRNVT-----NDGTLVLKDLDKSDSGTYTCVASSRHG-KYVWSGALLVDS 486
                E + Q   ++VT        T  +K + +  SG Y   A++  G  YV     ++D 
Sbjct: 16892 --KETIEQKTTKSVTIETTETTSTYTVKKVTREQSGKYKVTATNESGTTYVECTVQVIDK 16949

Query: 487   PINP 490
             P  P
Sbjct: 16950 PSRP 16953



 Score = 42.3 bits (95), Expect = 0.078
 Identities = 42/200 (21%), Positives = 74/200 (37%), Gaps = 4/200 (2%)

Query: 292   PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
             PP+ +  P +  V+        C     PEP + W+  G         +      + +  
Sbjct: 16056 PPTFSKKPKAQYVDENTNVILECRLVAVPEPDIVWTFNGEDIDEEEIKNVRIVTESDMHM 16115

Query: 352   GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
               +V+ I+   K+    T    A N  G + +   L V + D   P I+     N  +  
Sbjct: 16116 YCSVVHISKVKKSQE-GTYEVIATNREGEARLPITLKVRTTDKEAPQIL-EPLRNMVIRE 16173

Query: 412   KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
                 V     +  P P + WY +G+ +   + ++  +  TL L    KS+ G YT  A +
Sbjct: 16174 GESVVLSTQIVGNPPPKVTWYKDGKPV--KNAKSDKDLHTLTLITPQKSEKGEYTVKAVN 16231

Query: 472   RHGKYVWSGALLVDSPINPN 491
               G    +  L ++ P   N
Sbjct: 16232 PLGSVETTANLTIEEPAGGN 16251



 Score = 39.9 bits (89), Expect = 0.41
 Identities = 34/130 (26%), Positives = 55/130 (42%), Gaps = 7/130 (5%)

Query: 352  GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT-VTSDDDRPPPIITNGPSNQTLP 410
            G   L +  T   D+  T  C A N  G++ +   L  V     + P   ++    + L 
Sbjct: 4721 GTVALEVLGTKIEDT-GTYTCRATNKHGTAEISCNLECVDKPRGQKPRFTSHIQPLEGLK 4779

Query: 411  IKSMAVFPCTAICTPEPI--IAWYFEGEALIQNHRRNVTNDGTLVLKD---LDKSDSGTY 465
                A F CT I   +P   + WY  G+ +  ++R    +D   V+ D   L   DSG Y
Sbjct: 4780 DGQSAHFECTLIPVNDPDLKVEWYHNGKLMRHSNRIKTVSDFGYVVLDISYLQDHDSGEY 4839

Query: 466  TCVASSRHGK 475
             C A +++G+
Sbjct: 4840 VCRAWNKYGE 4849



 Score = 39.5 bits (88), Expect = 0.55
 Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 6/92 (6%)

Query: 389  VTSDDDRPPPIITNG-PSNQTLPIKSMAVFPCTAICTPEPI--IAWYFEGEALIQNHRRN 445
            VT D+   PP  T     N  +P      F C      +P   I W++ G  +    R +
Sbjct: 5303 VTEDEQPNPPKFTEEIKDNLDVPEGGPIHFDCRVEPVGDPTMRIEWFYNGHVMATGSRVH 5362

Query: 446  VTNDGTLVLKDLD---KSDSGTYTCVASSRHG 474
              ND   +  D+D     DSG YTC A+++ G
Sbjct: 5363 QLNDFGFIALDVDYIYARDSGEYTCRATNKWG 5394



 Score = 39.5 bits (88), Expect = 0.55
 Identities = 47/190 (24%), Positives = 70/190 (36%), Gaps = 17/190 (8%)

Query: 310  ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
            A+F     G P PT+ W  E      FP  +         F G ++L I      DS   
Sbjct: 6047 AKFEVEFEGEPNPTVKWYRES-----FPIQNSPDLQIHT-FSGKSILIIRQVFVEDSA-V 6099

Query: 370  IVCSAVNYAGSSFVRGKLTVTS------DDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
              C A N  G++     L V           +PP  +T   S  T+    +A F      
Sbjct: 6100 FSCVAENRGGTAKCSANLVVEERRRAGKGGIQPPSFVTTIQST-TVATGQLARFDAKVTG 6158

Query: 424  TPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
            T    + W   G  +  + +  +  +    TL++ +    DSG Y CVA +  G+    G
Sbjct: 6159 TRPLDVYWLKNGMKIQPSIKFKMLEEDSVHTLLIIEPFAEDSGRYECVAVNAAGEARCDG 6218

Query: 481  ALLVDSPINP 490
              +V SP  P
Sbjct: 6219 DCIVQSPSKP 6228



 Score = 39.1 bits (87), Expect = 0.72
 Identities = 32/137 (23%), Positives = 55/137 (40%), Gaps = 7/137 (5%)

Query: 196  LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
            L+  I P   T     +   G+ V+ +    G P P++   ++ GG        ++ +  
Sbjct: 971  LRREIAPRFTTPLSGKIVDQGADVSMEAIYDGFPSPEIKVEKN-GGQLFEDAHTRISNKC 1029

Query: 256  S---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLSPNSVNVESGNV 309
            +   + L  V + D G Y+  A N+VG  +++  L V     PP       +   + G  
Sbjct: 1030 NRVTIELKQVGVGDAGRYAVTASNTVGQSTSTADLVVKKTIFPPVFGRRLQAQVSKKGEK 1089

Query: 310  ARFTCTATGRPEPTMFW 326
                   TG PEPT+ W
Sbjct: 1090 LTMEVEVTGLPEPTVTW 1106



 Score = 39.1 bits (87), Expect = 0.72
 Identities = 20/66 (30%), Positives = 35/66 (53%), Gaps = 3/66 (4%)

Query: 420  TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL---DKSDSGTYTCVASSRHGKY 476
            T I  P+ ++ WYF G+ L   HR    +D  +V+ D+    + +SG Y   A +++G+ 
Sbjct: 4924 TPITDPDLVVEWYFNGKKLPHGHRFRTFHDFGIVILDILYCYEENSGVYEARARNKYGED 4983

Query: 477  VWSGAL 482
            V   +L
Sbjct: 4984 VTRASL 4989



 Score = 39.1 bits (87), Expect = 0.72
 Identities = 29/101 (28%), Positives = 43/101 (42%), Gaps = 8/101 (7%)

Query: 304  VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
            VE G+ ARF    TG P P + W + G+  +        +Y  T   DG+  L +  T +
Sbjct: 5739 VEEGDPARFCVRVTGHPRPRVMWLINGHTVV-----HGSRYKLTN--DGMFHLDVPKTRQ 5791

Query: 364  NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404
             D+    V  A N  G S    +L V +  D    ++ N P
Sbjct: 5792 YDTGKVEVI-ARNSVGESIATTELKVVARSDDYRNVLKNSP 5831



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 5/89 (5%)

Query: 392  DDDRPPPIITNGPSNQTLPIKSMAVFPC--TAICTPEPIIAWYFEGEALIQNHRRNVTND 449
            D  +PP  +T      TL   ++  F C    +  P   + W+F G+ L+  +R     D
Sbjct: 5585 DRKQPPRFVTQIKEQLTLTEMAVTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFQPIYD 5644

Query: 450  GTLVLKDLD---KSDSGTYTCVASSRHGK 475
               V  +       DSG Y C A++ +GK
Sbjct: 5645 FGYVAMNFGWVYPEDSGEYVCRATNLYGK 5673



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 28/79 (35%), Positives = 38/79 (48%), Gaps = 8/79 (10%)

Query: 216  GSSVTFQCRVG--GDPLPDVLWRRSAGGGNMPLG-RVKVLDDG---SLRLDNVILADEGE 269
            G  + F CRV   GDP   + W  +  G  M  G RV  L+D    +L +D +   D GE
Sbjct: 5327 GGPIHFDCRVEPVGDPTMRIEWFYN--GHVMATGSRVHQLNDFGFIALDVDYIYARDSGE 5384

Query: 270  YSCEAENSVGAVSASGYLT 288
            Y+C A N  G  + S  +T
Sbjct: 5385 YTCRATNKWGTATTSAKVT 5403



 Score = 37.5 bits (83), Expect = 2.2
 Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 8/117 (6%)

Query: 86  EATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWK 143
           ++ N+    RS  +++ +    +  EF+     KQ    + +  EC+  +G P P V+W 
Sbjct: 738 KSVNAPENRRSSQSSVEIIERHQCPEFKELFSDKQGEIDEVIKFECIV-KGKPTPKVHWF 796

Query: 144 KNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
            N Q +   G + +    G    L IQ       G+  C+A N AG + + +A L I
Sbjct: 797 FNDQPV--HGHNFLVSTSGERQVLTIQKLTHDAVGKISCVAENEAG-KATCVAFLNI 850



 Score = 37.5 bits (83), Expect = 2.2
 Identities = 30/131 (22%), Positives = 65/131 (49%), Gaps = 10/131 (7%)

Query: 157  MHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVV-AQT 215
            + ++   +L+++   ++   + Q +  ++   R S      ++I+P  +T P+ +   + 
Sbjct: 3016 VRIIAKNDLILETQNESGLQKIQYL-EDSTRHRRSEFVDEVVNIRPRFLTHPKSLTNTRE 3074

Query: 216  GSSVTFQCRVGG--DPLPDVLWRRSAGGGNMPLG-RVKVLDD-GSLRLD--NVILADEGE 269
            G    F+C++    DP   V W ++  G  + +G R + + D G + LD  ++I  D G 
Sbjct: 3075 GGHAHFECKIEPVTDPNLKVEWFKN--GRPITVGHRFRPIHDFGYVALDIVHLIAEDSGV 3132

Query: 270  YSCEAENSVGA 280
            Y+C A N +G+
Sbjct: 3133 YTCRAVNLIGS 3143



 Score = 37.5 bits (83), Expect = 2.2
 Identities = 26/98 (26%), Positives = 40/98 (40%), Gaps = 5/98 (5%)

Query: 392  DDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI--IAWYFEGEALIQNHRRNVTND 449
            +  +  P+ T    N  +     A F C  I   +P   + WY     L    R   TN+
Sbjct: 3188 ESTKQAPVFTTSLKNVEIKENQRAHFECRLIPVSDPSMRVEWYHNNLPLKSGSRFTETNN 3247

Query: 450  GTLVLKDLDKS---DSGTYTCVASSRHGKYVWSGALLV 484
               V  D+  +   D+GTYTC A +  G+ + S   +V
Sbjct: 3248 FGFVALDIMSTLPEDAGTYTCRAYNAVGEAITSAVAVV 3285



 Score = 37.5 bits (83), Expect = 2.2
 Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 3/65 (4%)

Query: 425  PEPIIAWYFEGEALIQNHRRNVTNDGTLV---LKDLDKSDSGTYTCVASSRHGKYVWSGA 481
            P+  + W   G+ +  ++R    +D   V   +K ++  DSGTYTC A +  G+ V S +
Sbjct: 3356 PKLTVEWLRNGQPIEASNRTTTMHDFGYVALNMKYVNPEDSGTYTCRAVNELGQAVTSAS 3415

Query: 482  LLVDS 486
            L+V S
Sbjct: 3416 LIVQS 3420



 Score = 37.5 bits (83), Expect = 2.2
 Identities = 30/95 (31%), Positives = 40/95 (42%), Gaps = 3/95 (3%)

Query: 197  KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS 256
            K   KP  ++  E    + G    F  RV G P P V+W  + G   +   R K+ +DG 
Sbjct: 5723 KPRTKPVFVSKLEPQTVEEGDPARFCVRVTGHPRPRVMWLIN-GHTVVHGSRYKLTNDGM 5781

Query: 257  LRLD--NVILADEGEYSCEAENSVGAVSASGYLTV 289
              LD       D G+    A NSVG   A+  L V
Sbjct: 5782 FHLDVPKTRQYDTGKVEVIARNSVGESIATTELKV 5816



 Score = 37.1 bits (82), Expect = 2.9
 Identities = 30/103 (29%), Positives = 43/103 (41%), Gaps = 6/103 (5%)

Query: 202  PYLITGPEDVVAQTGSSVTFQCRVG--GDPLPDVLWRRSAGGGNMPLGRVKVLDDGS--- 256
            P  IT P D+V    +   F+CR+    DP   V W  + G       R+K ++D     
Sbjct: 5175 PEFITSPFDMVIGENALAHFECRLQPINDPSMRVDWFHN-GKALWAGSRIKTINDFGFVI 5233

Query: 257  LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
            L +      D G Y+C+A N  G  + S  L V     I + P
Sbjct: 5234 LEIAGCYQRDSGLYTCKATNKHGEATVSCKLQVKGRQGIVMEP 5276



 Score = 36.3 bits (80), Expect = 5.1
 Identities = 25/71 (35%), Positives = 32/71 (45%), Gaps = 4/71 (5%)

Query: 120  AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG---NLVIQDARQTDAG 176
            AQG   + E    RG+P+P V W + G  LL     RM   +     +L+I      D G
Sbjct: 1824 AQGGNALFEGRL-RGNPKPFVTWTRKGAPLLESQKFRMSYNEATGDVSLLINQIGPGDEG 1882

Query: 177  RYQCIARNAAG 187
             Y C ARN  G
Sbjct: 1883 EYTCTARNQYG 1893



 Score = 36.3 bits (80), Expect = 5.1
 Identities = 38/148 (25%), Positives = 61/148 (41%), Gaps = 8/148 (5%)

Query: 14   IIEQPLDVT--VARHQPATLNCRA--GGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            +  QPL     +  HQ A    R    G P+  + WY+   ++   +  +     G   L
Sbjct: 3993 VFTQPLQNIDRINEHQTAHFEARLIPVGDPNLKVEWYRNEKIIEDSSRITKQHDFGFVSL 4052

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
              +H R   D GVY C A N  G A +  A++ V V     +++ +   S      + + 
Sbjct: 4053 DISHIR-KEDEGVYMCRAVNPLGEAVT-TASMRV-VSEASIQMDTQHPDSISRIHQLEKP 4109

Query: 130  LPPRGSPEPNVYWKKNGQTLLFDGDSRM 157
            L PR + EP   ++K   T L  G S +
Sbjct: 4110 LAPRPT-EPERLFEKPIFTQLLTGPSEL 4136



 Score = 36.3 bits (80), Expect = 5.1
 Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 4/90 (4%)

Query: 202  PYLITGPEDVVAQTGSSVTFQCRV--GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL 259
            P  IT   ++  +   +V F+C V    DP   + W  +            + D G   L
Sbjct: 4390 PVFITHLNNIECKESDNVRFECNVEPARDPTMSIEWFYNGQPLQAAAKFKSIYDFGYCAL 4449

Query: 260  D--NVILADEGEYSCEAENSVGAVSASGYL 287
            D  N    + G Y+C+A NS G+ + SG L
Sbjct: 4450 DLTNSYAENSGVYTCKATNSKGSATTSGTL 4479



 Score = 36.3 bits (80), Expect = 5.1
 Identities = 24/83 (28%), Positives = 33/83 (39%), Gaps = 4/83 (4%)

Query: 395  RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGT 451
            +PP I       Q +P +   V  C     P P I WYF    L  + +  +T       
Sbjct: 8088 KPPRITEKLRPRQCVP-EEPTVLECKVEGVPFPEIKWYFNDILLFASEKYEITVMEQVAK 8146

Query: 452  LVLKDLDKSDSGTYTCVASSRHG 474
            L +  +  SD G YTC A +  G
Sbjct: 8147 LKIAKVTPSDVGVYTCEAKNEAG 8169



 Score = 36.3 bits (80), Expect = 5.1
 Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 3/90 (3%)

Query: 10   EAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI-LPAGGLF 67
            E+P  +E+ +  V V   +   L C+  G P+P + WY     +  +   +I     G+ 
Sbjct: 8487 ESPRFVEELVQPVEVMDGEALLLTCQVTGKPTPKVEWYHNAEKITENKETTISQDLQGVC 8546

Query: 68   FLRATHGRVHSDAGVYWCEATNSYGTARSR 97
             L+ T     ++ G Y C ATN  G + S+
Sbjct: 8547 QLQITEVFPENE-GQYECVATNKIGKSVSK 8575



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 3/68 (4%)

Query: 425  PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDK---SDSGTYTCVASSRHGKYVWSGA 481
            P   I WYF G+ L    R  +T++   V  D+ +    D G YTC A ++ G+   S  
Sbjct: 4558 PNLFIEWYFNGKMLNHGSRFKMTSEFGFVTMDMIEVYARDQGIYTCKAYNKAGEAFTSTT 4617

Query: 482  LLVDSPIN 489
            +   S  N
Sbjct: 4618 IFCSSKEN 4625



 Score = 35.5 bits (78), Expect = 8.9
 Identities = 29/87 (33%), Positives = 39/87 (44%), Gaps = 5/87 (5%)

Query: 121  QGDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGR 177
            +G  V+LE  + PR  P   + W KNG +L   G       D G   L I   R  D+  
Sbjct: 4272 EGQHVLLEAQVEPRADPNLRIEWFKNGISLT-TGSRIRSTFDFGLVTLSINGLRADDSAI 4330

Query: 178  YQCIARNAAGTRESAIATLKIHIKPYL 204
            Y C A N  G   S  ++LKI  + +L
Sbjct: 4331 YTCKATNQVGEAVST-SSLKIEDRHWL 4356



 Score = 35.5 bits (78), Expect = 8.9
 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 7/90 (7%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIR--WYKGGVLVVSD-THRSILPAGGLFF 68
            P    Q   VTV   +     C+      P++R  WY+ G  + S   +R+I   G +  
Sbjct: 5447 PKFTTQITSVTVDEAEAVRFECQVEPKTDPSLRVEWYRNGKPLPSGHRYRNIFDMGFVSL 5506

Query: 69   -LRATHGRVHSDAGVYWCEATNSYGTARSR 97
             +   +G    D+G Y C A N+YG  R+R
Sbjct: 5507 DILYVYGE---DSGEYVCRAINNYGEDRTR 5533


>UniRef50_Q4TBR4 Cluster: Chromosome undetermined SCAF7099, whole
           genome shotgun sequence; n=2; Tetraodontidae|Rep:
           Chromosome undetermined SCAF7099, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 1000

 Score =  110 bits (264), Expect = 3e-22
 Identities = 75/256 (29%), Positives = 115/256 (44%), Gaps = 9/256 (3%)

Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195
           P  +V W KN   +++     +    G  L +   R++D+G Y CIA N  G    +   
Sbjct: 32  PPADVTWTKNNHPIMYYDPRYVTQAQGQMLTVPHVRESDSGEYCCIATNGVGEPAKSCGA 91

Query: 196 LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
           L++ +KP +   P ++     S     C   G+P PDV W +      +   RV +LD G
Sbjct: 92  LQLKMKPQIKRHPTNLTLLVESKAVLPCVTLGNPKPDVTWLKDDELIKIS-DRVTILDYG 150

Query: 256 SLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
           +L++ NV   D G+Y C A NS G ++S    + V  P  I   P    V  G +    C
Sbjct: 151 ALKIHNVRKEDAGQYRCVARNSFGLSISKPVTIEVQVPARILQVPKESKVAYGGLVSLQC 210

Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
            ATG P PT+ W   GN TI   G S D+  +  V   V  + ++      +  T + S 
Sbjct: 211 NATGNPVPTITWLENGN-TI--SGASVDEALSGDVIQSVLKVRVS----KPALYTCLASN 263

Query: 375 VNYAGSSFVRGKLTVT 390
            + AG++ V+    VT
Sbjct: 264 RHSAGANTVKASARVT 279



 Score =  100 bits (239), Expect = 3e-19
 Identities = 77/283 (27%), Positives = 125/283 (44%), Gaps = 10/283 (3%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
           AP II     + V     AT  C     P   + W K    ++    R +  A G   L 
Sbjct: 4   APRIITLLETLDVLTDHNATFICEVESRPPADVTWTKNNHPIMYYDPRYVTQAQGQM-LT 62

Query: 71  ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
             H R  SD+G Y C ATN  G        L +  ++ + +  P +         VL C+
Sbjct: 63  VPHVR-ESDSGEYCCIATNGVGEPAKSCGALQLK-MKPQIKRHPTNLTLLVESKAVLPCV 120

Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
              G+P+P+V W K+ + +      R+ ++D G L I + R+ DAG+Y+C+ARN+ G   
Sbjct: 121 T-LGNPKPDVTWLKDDELIKIS--DRVTILDYGALKIHNVRKEDAGQYRCVARNSFGLSI 177

Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250
           S   T+++ +   ++  P++     G  V+ QC   G+P+P + W  +    +       
Sbjct: 178 SKPVTIEVQVPARILQVPKESKVAYGGLVSLQCNATGNPVPTITWLENGNTISGASVDEA 237

Query: 251 VLDDGSLRLDNVILADEGEYSCEAEN--SVGA--VSASGYLTV 289
           +  D    +  V ++    Y+C A N  S GA  V AS  +TV
Sbjct: 238 LSGDVIQSVLKVRVSKPALYTCLASNRHSAGANTVKASARVTV 280



 Score = 63.7 bits (148), Expect = 3e-08
 Identities = 71/275 (25%), Positives = 106/275 (38%), Gaps = 17/275 (6%)

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLD 260
           P +IT  E +   T  + TF C V   P  DV W ++         R      G  L + 
Sbjct: 5   PRIITLLETLDVLTDHNATFICEVESRPPADVTWTKNNHPIMYYDPRYVTQAQGQMLTVP 64

Query: 261 NVILADEGEYSCEAENSVGAVSAS-GYLTVYDPPSINLSPNSVNVESGNVARFTCTATGR 319
           +V  +D GEY C A N VG  + S G L +   P I   P ++ +   + A   C   G 
Sbjct: 65  HVRESDSGEYCCIATNGVGEPAKSCGALQLKMKPQIKRHPTNLTLLVESKAVLPCVTLGN 124

Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379
           P+P + W  +     I   ++   Y A         L I++  K D+     C A N  G
Sbjct: 125 PKPDVTWLKDDELIKISDRVTILDYGA---------LKIHNVRKEDA-GQYRCVARNSFG 174

Query: 380 SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI 439
            S  +    VT +   P  I+   P    +    +    C A   P P I W   G  + 
Sbjct: 175 LSISK---PVTIEVQVPARIL-QVPKESKVAYGGLVSLQCNATGNPVPTITWLENGNTIS 230

Query: 440 -QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
             +    ++ D    +  +  S    YTC+AS+RH
Sbjct: 231 GASVDEALSGDVIQSVLKVRVSKPALYTCLASNRH 265



 Score = 63.7 bits (148), Expect = 3e-08
 Identities = 60/246 (24%), Positives = 107/246 (43%), Gaps = 19/246 (7%)

Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
           P I     +++V + + A F C    RP   + W+ + N  I++      +Y   A    
Sbjct: 5   PRIITLLETLDVLTDHNATFICEVESRPPADVTWT-KNNHPIMYYD---PRYVTQAQGQM 60

Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR-GKLTVTSDDDRPPPIITNGPSNQTLPI 411
           +TV  + ++D  +      C A N  G      G L +     +  P I   P+N TL +
Sbjct: 61  LTVPHVRESDSGE----YCCIATNGVGEPAKSCGALQL-----KMKPQIKRHPTNLTLLV 111

Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
           +S AV PC  +  P+P + W  + E +  + R  + + G L + ++ K D+G Y CVA +
Sbjct: 112 ESKAVLPCVTLGNPKPDVTWLKDDELIKISDRVTILDYGALKIHNVRKEDAGQYRCVARN 171

Query: 472 RHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSV-TLSWSQN-NK 529
             G  + S  + ++  +   I   +    S +       +  N T   V T++W +N N 
Sbjct: 172 SFGLSI-SKPVTIEVQVPARI--LQVPKESKVAYGGLVSLQCNATGNPVPTITWLENGNT 228

Query: 530 IGSSSI 535
           I  +S+
Sbjct: 229 ISGASV 234


>UniRef50_Q0E8J3 Cluster: CG33484-PD, isoform D; n=9; Sophophora|Rep:
            CG33484-PD, isoform D - Drosophila melanogaster (Fruit
            fly)
          Length = 3651

 Score =  110 bits (264), Expect = 3e-22
 Identities = 117/420 (27%), Positives = 184/420 (43%), Gaps = 48/420 (11%)

Query: 119  SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGR 177
            S +GD  V EC    G+PEP V W K+G ++  + D +     G   LVI++    D+ R
Sbjct: 1388 SREGDRFVFEC-EVTGTPEPAVEWFKDGISIQTNSDYKTTFDKGICRLVIEETFAADSAR 1446

Query: 178  YQCIARNAAGTRESAIATLKIH--------IKPYLITGPEDVVAQTGSSVTFQCRVGGDP 229
            + C A N  GT ++  ATL +         + P ++   +   A  GSS  F C V G P
Sbjct: 1447 FSCRASNLVGTCDTN-ATLSVRENAAEVQLVPPRILRFLQSGKATEGSSFQFACVVAGVP 1505

Query: 230  LPDVLWRRSAGGGNMPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYL 287
            LP V W ++    +     V   ++G  +L+ + V L D+  Y+C A N  G    S  L
Sbjct: 1506 LPTVQWFKNDKCIDDSPDYVISYNNGEATLKFEEVFLEDDAVYTCSASNPAGIEHCSASL 1565

Query: 288  TV--YDP---PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRD 342
             V   +P   PS  +  ++     G   +      G P P ++W   G      P   RD
Sbjct: 1566 IVEPLEPTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWLHNGK-----PFQPRD 1620

Query: 343  KYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF------VRGKL-TVTSDDDR 395
              +      G   L I     ND+  + V SA N AG ++      V+G+L   TSD + 
Sbjct: 1621 SKYEY----GRVTLIIPQAYPNDA-GSYVLSAKNLAGEAYTSCNVIVKGRLPNETSDSEM 1675

Query: 396  PPPIITNGPSNQTLPIKSMAVFP-------CTAICTPEPIIAWYFEGEALIQNHRRNVTN 448
               I    P+   LP+K +++F        C  +  PEP + WY     + ++    +  
Sbjct: 1676 ASDIEPIKPAVH-LPLKDVSIFEGKPVRLDCVIVGQPEPEVIWYHNERPVKESADVQLLF 1734

Query: 449  DG---TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRA-ADVSSLP 504
             G   +L+++++ + D+G Y  VA +  G+   S  L V +P+N      RA A+  SLP
Sbjct: 1735 QGDRCSLIIQEVYQEDAGHYKVVAINSAGEASSSCELKV-TPLNQAEPATRAQAERQSLP 1793



 Score = 87.4 bits (207), Expect = 2e-15
 Identities = 105/435 (24%), Positives = 172/435 (39%), Gaps = 43/435 (9%)

Query: 14   IIEQPLDVTVARHQPA-TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRAT 72
            +  +PL   V+R        C   G+P PA+ W+K G+ + +++        G+  L   
Sbjct: 1378 LFTRPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTFDKGICRL-VI 1436

Query: 73   HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-------ESKQSAQGDTV 125
                 +D+  + C A+N  GT  + NATL V     E +L P       +S ++ +G + 
Sbjct: 1437 EETFAADSARFSCRASNLVGTCDT-NATLSVRENAAEVQLVPPRILRFLQSGKATEGSSF 1495

Query: 126  VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARN 184
               C+   G P P V W KN + +    D  +   +G   L  ++    D   Y C A N
Sbjct: 1496 QFACVVA-GVPLPTVQWFKNDKCIDDSPDYVISYNNGEATLKFEEVFLEDDAVYTCSASN 1554

Query: 185  AAGTRESAIATLKIHIKPYLITG---P-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
             AG    + + +   ++P  +     P  + +A+ G  +  +  VGG P P+V W  +  
Sbjct: 1555 PAGIEHCSASLIVEPLEPTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWLHNGK 1614

Query: 241  -----GGNMPLGRVKVL-------DDGSLRLDNVILADEGEYSCEA---ENSVGAVSASG 285
                       GRV ++       D GS  L    LA E   SC            S S 
Sbjct: 1615 PFQPRDSKYEYGRVTLIIPQAYPNDAGSYVLSAKNLAGEAYTSCNVIVKGRLPNETSDSE 1674

Query: 286  YLTVYDP--PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDK 343
              +  +P  P+++L    V++  G   R  C   G+PEP + W     R +      ++ 
Sbjct: 1675 MASDIEPIKPAVHLPLKDVSIFEGKPVRLDCVIVGQPEPEVIW-YHNERPV------KES 1727

Query: 344  YHATAVFDGVTV-LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN 402
                 +F G    L I +  + D+ +  V  A+N AG +    +L VT  +   P     
Sbjct: 1728 ADVQLLFQGDRCSLIIQEVYQEDAGHYKVV-AINSAGEASSSCELKVTPLNQAEPATRAQ 1786

Query: 403  GPSNQTLPIKSMAVF 417
                Q+LP  S   F
Sbjct: 1787 A-ERQSLPKDSQPKF 1800



 Score = 66.9 bits (156), Expect = 3e-09
 Identities = 77/322 (23%), Positives = 114/322 (35%), Gaps = 24/322 (7%)

Query: 204  LITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL--D 260
            L T P +D V++ G    F+C V G P P V W +               D G  RL  +
Sbjct: 1378 LFTRPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTFDKGICRLVIE 1437

Query: 261  NVILADEGEYSCEAENSVGAVSASGYLTVYD--------PPSINLSPNSVNVESGNVARF 312
                AD   +SC A N VG    +  L+V +        PP I     S     G+  +F
Sbjct: 1438 ETFAADSARFSCRASNLVGTCDTNATLSVRENAAEVQLVPPRILRFLQSGKATEGSSFQF 1497

Query: 313  TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
             C   G P PT+ W  + ++ I     S D  +  +  +G   L   +    D      C
Sbjct: 1498 ACVVAGVPLPTVQW-FKNDKCI---DDSPD--YVISYNNGEATLKFEEVFLEDDA-VYTC 1550

Query: 373  SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
            SA N AG       L V   +    P      SN    +             P P + W 
Sbjct: 1551 SASNPAGIEHCSASLIVEPLEPTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWL 1610

Query: 433  FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPI-NPN 491
              G+       +      TL++     +D+G+Y   A +  G+   S  ++V   + N  
Sbjct: 1611 HNGKPFQPRDSKYEYGRVTLIIPQAYPNDAGSYVLSAKNLAGEAYTSCNVIVKGRLPNET 1670

Query: 492  IHFFRAADVSSLPGPPTKPITH 513
                 A+D+      P KP  H
Sbjct: 1671 SDSEMASDIE-----PIKPAVH 1687



 Score = 62.1 bits (144), Expect = 9e-08
 Identities = 48/159 (30%), Positives = 74/159 (46%), Gaps = 6/159 (3%)

Query: 37   GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
            G PSP I+  K G  +  D H  I        +      V  DAG Y   A+N+ G + S
Sbjct: 2154 GFPSPEIKVEKNGGQLFEDAHTRISNKCNRVTIELKQVGV-GDAGRYAVTASNTVGQSTS 2212

Query: 97   R-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155
              +  +   +    F    +++ S +G+ + +E +   G PEP V W K+ + L   G S
Sbjct: 2213 TADLVVKKTIFPPVFGRRLQAQVSKKGEKLTME-VEVTGLPEPTVTWLKDDKPLKDAGIS 2271

Query: 156  RMHLVDGGN---LVIQDARQTDAGRYQCIARNAAGTRES 191
               L+  GN   L+I+ A+ TD+G+Y   A NA G  +S
Sbjct: 2272 EHRLLAQGNSYRLIIEKAQTTDSGKYMVRATNAGGEAKS 2310



 Score = 48.4 bits (110), Expect = 0.001
 Identities = 31/93 (33%), Positives = 44/93 (47%), Gaps = 6/93 (6%)

Query: 201  KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD--DG--S 256
            +P  IT  +D+    G +  F+C V   P P V W  +  GG +  G    ++  +G   
Sbjct: 3552 QPLFITPLKDIAVGVGGTARFECIVQAHPQPQVNWTHN--GGLLESGSRHCIEYRNGVCR 3609

Query: 257  LRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
            L L      D G Y+C A N +GA + SG LTV
Sbjct: 3610 LTLPQAYPDDNGSYACTAINPLGAATTSGNLTV 3642



 Score = 41.1 bits (92), Expect = 0.18
 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 7/90 (7%)

Query: 302  VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
            + V  G  ARF C     P+P + W+  G    +    SR   H     +GV  LT+   
Sbjct: 3562 IAVGVGGTARFECIVQAHPQPQVNWTHNGG---LLESGSR---HCIEYRNGVCRLTLPQA 3615

Query: 362  DKNDSRNTIVCSAVNYAGSSFVRGKLTVTS 391
              +D+  +  C+A+N  G++   G LTV+S
Sbjct: 3616 YPDDN-GSYACTAINPLGAATTSGNLTVSS 3644



 Score = 39.1 bits (87), Expect = 0.72
 Identities = 32/137 (23%), Positives = 55/137 (40%), Gaps = 7/137 (5%)

Query: 196  LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
            L+  I P   T     +   G+ V+ +    G P P++   ++ GG        ++ +  
Sbjct: 2123 LRREIAPRFTTPLSGKIVDQGADVSMEAIYDGFPSPEIKVEKN-GGQLFEDAHTRISNKC 2181

Query: 256  S---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLSPNSVNVESGNV 309
            +   + L  V + D G Y+  A N+VG  +++  L V     PP       +   + G  
Sbjct: 2182 NRVTIELKQVGVGDAGRYAVTASNTVGQSTSTADLVVKKTIFPPVFGRRLQAQVSKKGEK 2241

Query: 310  ARFTCTATGRPEPTMFW 326
                   TG PEPT+ W
Sbjct: 2242 LTMEVEVTGLPEPTVTW 2258



 Score = 37.5 bits (83), Expect = 2.2
 Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 8/117 (6%)

Query: 86   EATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWK 143
            ++ N+    RS  +++ +    +  EF+     KQ    + +  EC+  +G P P V+W 
Sbjct: 1890 KSVNAPENRRSSQSSVEIIERHQCPEFKELFSDKQGEIDEVIKFECIV-KGKPTPKVHWF 1948

Query: 144  KNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
             N Q +   G + +    G    L IQ       G+  C+A N AG + + +A L I
Sbjct: 1949 FNDQPV--HGHNFLVSTSGERQVLTIQKLTHDAVGKISCVAENEAG-KATCVAFLNI 2002


>UniRef50_UPI00015B41E3 Cluster: PREDICTED: similar to fasciclin ii
           (fas ii); n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to fasciclin ii (fas ii) - Nasonia vitripennis
          Length = 772

 Score =  109 bits (263), Expect = 3e-22
 Identities = 107/415 (25%), Positives = 174/415 (41%), Gaps = 30/415 (7%)

Query: 80  AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
           AG Y C  T +     S+   +   ++   +   P ++    G+   ++C   R  P P 
Sbjct: 116 AGQYICRGTYANTELLSKTVIIET-IVAITWDDAPLNQFPILGEDFAIKC-QVRARPSPK 173

Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR-NAAGTRESAIATLKI 198
           V W  NG+ +  +     ++++   L I++ +++D G Y C A     G  +     +++
Sbjct: 174 VDWLFNGEVIRTNDH---YVIETHALRIKNVKESDDGIYTCRASVEQTGELQERAIRVEV 230

Query: 199 HIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDD-G 255
           H +P ++     V   T G S    C+  G P P   W ++    N+ +  R  V +D G
Sbjct: 231 HTRPSIVEAENSVYEVTEGESAQILCKGTGKPPPKFTWIKTLTKENLAVTDRFSVNEDTG 290

Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315
            L + NV   D GEY C A N+ G    +  + V   P I    N   +  G     +C 
Sbjct: 291 LLTISNVKRDDSGEYQCTATNAAGMAIMNIQVNVIVKPKIMEFLNQ-TIAQGEKTVLSCK 349

Query: 316 ATGRPEPTMFWSVEGNRTIIFPGM--SRDKYHATAVFD---GVTV--LTINDTDKNDSRN 368
           A G+P PT+ +    +      G+    D+ H T  FD   G TV  LTI+ T ++D   
Sbjct: 350 AFGKPPPTITFRKHTSEKPFIRGVQPEDDRIHLTNDFDDQQGETVGNLTIDHTLRSDD-G 408

Query: 369 TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPE 426
              C A N  G +F  G LTV    + PP   +   SN+T+           C A   P 
Sbjct: 409 LYECIANNKGGMAFKNGHLTV----EFPPSFAS--MSNRTIYSWDNRPVNLTCIAESIPN 462

Query: 427 PIIAWYFEGEALIQNHRRNVTND----GTLVLKDLDKSDSGTYTCVASSRHGKYV 477
             I W + G   ++N ++    D     +L +K LD+     Y C A +R G+ +
Sbjct: 463 ATIHWTYYGNDKVENDQQITVYDNGPISSLYIKPLDRRYYTQYKCHAKNRLGEAI 517



 Score =  100 bits (239), Expect = 3e-19
 Identities = 84/334 (25%), Positives = 137/334 (41%), Gaps = 26/334 (7%)

Query: 16  EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75
           + PL+      +   + C+    PSP + W   G ++ ++ H  I        LR  + +
Sbjct: 147 DAPLNQFPILGEDFAIKCQVRARPSPKVDWLFNGEVIRTNDHYVIETHA----LRIKNVK 202

Query: 76  VHSDAGVYWCEAT-NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRG 134
             SD G+Y C A+    G  + R   + V         E    +  +G++  + C    G
Sbjct: 203 -ESDDGIYTCRASVEQTGELQERAIRVEVHTRPSIVEAENSVYEVTEGESAQILC-KGTG 260

Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
            P P   W K           R  +  D G L I + ++ D+G YQC A NAAG     I
Sbjct: 261 KPPPKFTWIKTLTKENLAVTDRFSVNEDTGLLTISNVKRDDSGEYQCTATNAAGMAIMNI 320

Query: 194 ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG------GGNMPLG 247
             + + +KP ++      +AQ G      C+  G P P + +R+         G      
Sbjct: 321 -QVNVIVKPKIMEFLNQTIAQ-GEKTVLSCKAFGKPPPTITFRKHTSEKPFIRGVQPEDD 378

Query: 248 RVKVLDD---------GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-NL 297
           R+ + +D         G+L +D+ + +D+G Y C A N  G    +G+LTV  PPS  ++
Sbjct: 379 RIHLTNDFDDQQGETVGNLTIDHTLRSDDGLYECIANNKGGMAFKNGHLTVEFPPSFASM 438

Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGN 331
           S  ++          TC A   P  T+ W+  GN
Sbjct: 439 SNRTIYSWDNRPVNLTCIAESIPNATIHWTYYGN 472



 Score = 75.8 bits (178), Expect = 7e-12
 Identities = 88/354 (24%), Positives = 150/354 (42%), Gaps = 37/354 (10%)

Query: 155 SRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVA 213
           + +H  D   +L     ++  AG+Y C    A     S    ++  +       P +   
Sbjct: 95  TELHPQDNSISLFFNSLQEDQAGQYICRGTYANTELLSKTVIIETIVAITWDDAPLNQFP 154

Query: 214 QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCE 273
             G     +C+V   P P V W  +  G  +      V++  +LR+ NV  +D+G Y+C 
Sbjct: 155 ILGEDFAIKCQVRARPSPKVDWLFN--GEVIRTNDHYVIETHALRIKNVKESDDGIYTCR 212

Query: 274 AE-NSVGAVSASGY-LTVYDPPSINLSPNSV-NVESGNVARFTCTATGRPEPTMFWSVEG 330
           A     G +      + V+  PSI  + NSV  V  G  A+  C  TG+P P   W    
Sbjct: 213 ASVEQTGELQERAIRVEVHTRPSIVEAENSVYEVTEGESAQILCKGTGKPPPKFTWI--- 269

Query: 331 NRTIIFPGMS-RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389
            +T+    ++  D++   +V +   +LTI++  ++DS     C+A N AG + +  ++ V
Sbjct: 270 -KTLTKENLAVTDRF---SVNEDTGLLTISNVKRDDS-GEYQCTATNAAGMAIMNIQVNV 324

Query: 390 TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW--YFEGEALI-----QNH 442
                  P I+     NQT+      V  C A   P P I +  +   +  I     ++ 
Sbjct: 325 IVK----PKIMEF--LNQTIAQGEKTVLSCKAFGKPPPTITFRKHTSEKPFIRGVQPEDD 378

Query: 443 RRNVTND---------GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
           R ++TND         G L +    +SD G Y C+A+++ G    +G L V+ P
Sbjct: 379 RIHLTNDFDDQQGETVGNLTIDHTLRSDDGLYECIANNKGGMAFKNGHLTVEFP 432



 Score = 42.3 bits (95), Expect = 0.078
 Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 1/91 (1%)

Query: 402 NGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSD 461
           + P NQ   +       C     P P + W F GE +I+ +   V     L +K++ +SD
Sbjct: 147 DAPLNQFPILGEDFAIKCQVRARPSPKVDWLFNGE-VIRTNDHYVIETHALRIKNVKESD 205

Query: 462 SGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
            G YTC AS      +   A+ V+    P+I
Sbjct: 206 DGIYTCRASVEQTGELQERAIRVEVHTRPSI 236


>UniRef50_UPI00015B50B3 Cluster: PREDICTED: similar to cell adhesion
           molecule; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to cell adhesion molecule - Nasonia vitripennis
          Length = 977

 Score =  109 bits (262), Expect = 5e-22
 Identities = 83/281 (29%), Positives = 130/281 (46%), Gaps = 25/281 (8%)

Query: 30  TLNCRAGGSPSPAIRWYKGGV---LVVSD-----THRSILPAGGLFFLRATHGRVHSDAG 81
           TL+C A G P+P   W+K       +VS      +H     +GG   + + +     D G
Sbjct: 260 TLSCLADGYPTPTYEWFKEDFENDRLVSKKIDPLSHNRYTISGGTLIIFSPNQT--EDRG 317

Query: 82  VYWCEATNSYGTARSRNATLHVAVLREEFR---LEPESKQSAQGDTVVLECLPPRGSPEP 138
            Y C+ATN +GT RS +  +  A L+  F+   LEPE+  +A+G  V L C  P  +P P
Sbjct: 318 TYHCKATNKFGTIRSESVDIFAA-LKPSFKKRPLEPET-YAAEGGNVTLIC-NPEAAPRP 374

Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
              WKK+G  L   G  R  + D G+L+I    + D G Y C   N  G  ES    + +
Sbjct: 375 KFTWKKDGNVLGSGG--RRRITDTGSLIISPVSRDDEGTYVCQVSNEYGNDESRGRLIVL 432

Query: 199 HIKPYLITG-PEDVVAQTGSSVTFQCRVGGDPLPDV--LWRRS---AGGGNMPLGRVKVL 252
           +  P LI   P  +      + T +C    D + DV  +W  +       ++      V+
Sbjct: 433 N-GPVLIESLPPTIRTAVNLNQTLRCMAYTDEMLDVAYIWMHNDMRIRDKDLKANPHIVI 491

Query: 253 DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
           + G L + N   A+ G+Y C  +++VG +S+   +T+  PP
Sbjct: 492 NGGQLDIINATFAEAGDYECIVKSTVGRISSRTTITIEGPP 532



 Score = 71.3 bits (167), Expect = 1e-10
 Identities = 61/199 (30%), Positives = 81/199 (40%), Gaps = 17/199 (8%)

Query: 110 FRLEPESK-----QSAQGDTVVLECLPPRGSPEPNVYWKK----NGQTLLFDGDSRMH-- 158
           F  +PE+K     +    + V L CL   G P P   W K    N + +    D   H  
Sbjct: 239 FTKQPENKVFDVTKRVVNNDVTLSCLAD-GYPTPTYEWFKEDFENDRLVSKKIDPLSHNR 297

Query: 159 -LVDGGNLVIQDARQT-DAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP--EDVVAQ 214
             + GG L+I    QT D G Y C A N  GT  S    +   +KP     P   +  A 
Sbjct: 298 YTISGGTLIIFSPNQTEDRGTYHCKATNKFGTIRSESVDIFAALKPSFKKRPLEPETYAA 357

Query: 215 TGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEA 274
            G +VT  C     P P   W++  G      GR ++ D GSL +  V   DEG Y C+ 
Sbjct: 358 EGGNVTLICNPEAAPRPKFTWKKD-GNVLGSGGRRRITDTGSLIISPVSRDDEGTYVCQV 416

Query: 275 ENSVGAVSASGYLTVYDPP 293
            N  G   + G L V + P
Sbjct: 417 SNEYGNDESRGRLIVLNGP 435



 Score = 65.7 bits (153), Expect = 7e-09
 Identities = 131/578 (22%), Positives = 213/578 (36%), Gaps = 74/578 (12%)

Query: 266 DEGEYSCEAENSVGAV-SASGYLTVYDPPSIN---LSPNSVNVESGNVARFTCTATGRPE 321
           D G Y C+A N  G + S S  +     PS     L P +   E GNV    C     P 
Sbjct: 315 DRGTYHCKATNKFGTIRSESVDIFAALKPSFKKRPLEPETYAAEGGNVT-LICNPEAAPR 373

Query: 322 PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381
           P   W  +GN   +     R +   T        L I+   ++D   T VC   N  G+ 
Sbjct: 374 PKFTWKKDGN---VLGSGGRRRITDTGS------LIISPVSRDDE-GTYVCQVSNEYGND 423

Query: 382 FVRGKLTVTSD----DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437
             RG+L V +     +  PP I T    NQTL  + MA    T        I  + +   
Sbjct: 424 ESRGRLIVLNGPVLIESLPPTIRTAVNLNQTL--RCMAY---TDEMLDVAYIWMHNDMRI 478

Query: 438 LIQNHRRN---VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHF 494
             ++ + N   V N G L + +   +++G Y C+  S  G+      + ++ P       
Sbjct: 479 RDKDLKANPHIVINGGQLDIINATFAEAGDYECIVKSTVGRISSRTTITIEGP------- 531

Query: 495 FRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTP 554
                    PGPP      NV  TSV LSW+ +       I  Y +   +    +  N  
Sbjct: 532 ---------PGPPGGIQVLNVVKTSVDLSWT-DGAYNGRPIDRYTISAKTNWNQTWFNLT 581

Query: 555 RNSRGWVVIARRVHQTHYVVKSLI-PGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNS 613
            +   + +  R   +    +++++ P  TY F ++  N  G   PS  S   +   D   
Sbjct: 582 EDFTAYTIGDRNTGRKRAHLENVLRPFTTYEFRIQAGNELGYGPPSLPSPQYSTPSDK-- 639

Query: 614 LWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEIL--NFYYLEGLF--IYFR 669
                 +   +  R                +   TIK  W+ L  +  Y  G+F  +Y+R
Sbjct: 640 -----PIVAPSNIRGG-----------GGKLGDLTIK--WDPLKSSEQYGPGIFYKVYWR 681

Query: 670 PLDNITIEYEMKTILHSN-DVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLD 728
                +    +    H N  +S   I S   YT+YE  +        G  S      + +
Sbjct: 682 RKKGESEFQSLALKEHGNVGMSVVPIQSQYYYTEYEVMVQAANDVGYGPKSEIFTIYSAE 741

Query: 729 DVPDGPPINIEMFILNTTTVHLKWSPPELQLQ--NGIITGYNVVVNWLDVPANKSMVAIN 786
           D+P   P  +  F  N T +++ W+P E   +   G + G+ +   W +    +  V   
Sbjct: 742 DMPQVAPQLVTAFSYNGTALNVTWNPIEQTRERVRGRLIGHRIKY-WKENGREEDAVYYL 800

Query: 787 TTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQK 824
           +   +  SL++  L     Y V++ A    G GP S++
Sbjct: 801 SRTTRPWSLVV-GLQPDTYYYVKVMAYNSAGEGPESER 837



 Score = 57.2 bits (132), Expect = 3e-06
 Identities = 46/179 (25%), Positives = 67/179 (37%), Gaps = 6/179 (3%)

Query: 308 NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY-HATAVFDGVTVLTINDTDKNDS 366
           N    +C A G P PT  W  E            D   H      G T++  +     D 
Sbjct: 257 NDVTLSCLADGYPTPTYEWFKEDFENDRLVSKKIDPLSHNRYTISGGTLIIFSPNQTED- 315

Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTP 425
           R T  C A N  G+  +R + +V       P         +T   +   V   C     P
Sbjct: 316 RGTYHCKATNKFGT--IRSE-SVDIFAALKPSFKKRPLEPETYAAEGGNVTLICNPEAAP 372

Query: 426 EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
            P   W  +G  L    RR +T+ G+L++  + + D GTY C  S+ +G     G L+V
Sbjct: 373 RPKFTWKKDGNVLGSGGRRRITDTGSLIISPVSRDDEGTYVCQVSNEYGNDESRGRLIV 431



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 42/170 (24%), Positives = 76/170 (44%), Gaps = 8/170 (4%)

Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
           +  L+  T Y   ++ +    EG  S   + +T    P  PP ++ +F  N T+V + W 
Sbjct: 810 VVGLQPDTYYYVKVMAYNSAGEGPESERYLQRTFRRAPQKPPSSVNVFGRNPTSVRVTWR 869

Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTV-HQATSLIMTNLTSGVSYSVQIAA 812
             +       + G+ + V W +   + S  A++T V   A   I+ NL  G  Y +++ A
Sbjct: 870 YVQNPNGEEPVIGFKIRV-W-ETDQDMS-TAVDTLVPPDAIVAIIENLGVGKEYFLRMLA 926

Query: 813 ETIIGLGPFSQKVY-FNI-DSRSVGLDLLSRYPMNGEVSIVAGDFVMETW 860
            +  G G  S   + F + D+   G D  SR  ++  + IV+  F ++ W
Sbjct: 927 YSNGGDGRMSSPAHRFRMGDATDYGND-ASRRKLDSMLLIVSILF-LKVW 974


>UniRef50_A7SVH6 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 336

 Score =  109 bits (262), Expect = 5e-22
 Identities = 100/357 (28%), Positives = 151/357 (42%), Gaps = 40/357 (11%)

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
           G  +VL+C P  G P P+  W  NG+ L   G + +    G  LVI      D+G+YQC 
Sbjct: 3   GAKLVLQC-PSTGVPLPSTSWSLNGEPLEKGGRADLR---GTELVIPAVAGVDSGKYQCT 58

Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS--- 238
           A N       A  +LK    P ++T  + V   TG+ V+  C V G P P V W ++   
Sbjct: 59  ASNVIALDSRASDSLKSR-DPVIVTIGDKVETLTGTEVSIICPVEGLPPPKVTWAKNGPI 117

Query: 239 AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
           A G    + R   L   S +     + D G YSC A N++G  +A     V    ++ + 
Sbjct: 118 ASGDKFTIARSTDLVFNSGKAS---VFDSGRYSCRAVNNLGQDTAYSEFIVNATFTVTIG 174

Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
            N V+   G+    TCTA G P P + W  +G  T+                 G    T+
Sbjct: 175 AN-VSALRGSSITLTCTAEGLPVPAVVWK-KGGATLQ---------------QGGRAFTL 217

Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
           + T+  DS     C A N  G++     +T+      P      G +  ++         
Sbjct: 218 SSTESADS-GRYDCVATNLKGTAMASSAVTIHGTLGDPHLGRKVGGTRTSIS-------- 268

Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHG 474
           C A   P P+I W   GE+++      +  DG+ L+L +  K D+G Y C+AS+  G
Sbjct: 269 CPATGFPNPLIRWSRNGESVVPGGHLKI--DGSKLLLTNPQKEDNGVYKCLASNPGG 323



 Score = 89.4 bits (212), Expect = 5e-16
 Identities = 82/306 (26%), Positives = 124/306 (40%), Gaps = 26/306 (8%)

Query: 31  LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
           L C + G P P+  W   G  +       +   G    + A  G    D+G Y C A+N 
Sbjct: 8   LQCPSTGVPLPSTSWSLNGEPLEKGGRADL--RGTELVIPAVAG---VDSGKYQCTASNV 62

Query: 91  YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
                  + +L     R+   +    K      T V    P  G P P V W KNG   +
Sbjct: 63  IALDSRASDSLKS---RDPVIVTIGDKVETLTGTEVSIICPVEGLPPPKVTWAKNGP--I 117

Query: 151 FDGDSRMHLVDGGNLVIQDARQT--DAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208
             GD +  +    +LV    + +  D+GRY C A N  G +++A +   ++   + +T  
Sbjct: 118 ASGD-KFTIARSTDLVFNSGKASVFDSGRYSCRAVNNLG-QDTAYSEFIVNAT-FTVTIG 174

Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268
            +V A  GSS+T  C   G P+P V+W++  GG  +  G        +  L +   AD G
Sbjct: 175 ANVSALRGSSITLTCTAEGLPVPAVVWKK--GGATLQQG------GRAFTLSSTESADSG 226

Query: 269 EYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328
            Y C A N  G   AS  +T++        P+      G     +C ATG P P + WS 
Sbjct: 227 RYDCVATNLKGTAMASSAVTIHGTLG---DPHLGRKVGGTRTSISCPATGFPNPLIRWSR 283

Query: 329 EGNRTI 334
            G   +
Sbjct: 284 NGESVV 289



 Score = 81.4 bits (192), Expect = 1e-13
 Identities = 75/259 (28%), Positives = 109/259 (42%), Gaps = 28/259 (10%)

Query: 33  CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS-DAGVYWCEATNSY 91
           C   G P P + W K G +   D   +I  +  L F     G+    D+G Y C A N+ 
Sbjct: 99  CPVEGLPPPKVTWAKNGPIASGDKF-TIARSTDLVF---NSGKASVFDSGRYSCRAVNNL 154

Query: 92  GTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
           G    ++      ++   F +   +  SA +G ++ L C    G P P V WKK G TL 
Sbjct: 155 G----QDTAYSEFIVNATFTVTIGANVSALRGSSITLTCTA-EGLPVPAVVWKKGGATLQ 209

Query: 151 FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED 210
             G +           +      D+GRY C+A N  GT   A+A+  + I   L  G   
Sbjct: 210 QGGRA---------FTLSSTESADSGRYDCVATNLKGT---AMASSAVTIHGTL--GDPH 255

Query: 211 VVAQTGSSVT-FQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGE 269
           +  + G + T   C   G P P + W R+ G   +P G +K+ D   L L N    D G 
Sbjct: 256 LGRKVGGTRTSISCPATGFPNPLIRWSRN-GESVVPGGHLKI-DGSKLLLTNPQKEDNGV 313

Query: 270 YSCEAENSVGAVSASGYLT 288
           Y C A N  G  +A+  +T
Sbjct: 314 YKCLASNPGGDATATSNMT 332



 Score = 76.6 bits (180), Expect = 4e-12
 Identities = 53/178 (29%), Positives = 85/178 (47%), Gaps = 22/178 (12%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
           A + +    +V+  R    TL C A G P PA+ W KGG         ++   G  F L 
Sbjct: 167 ATFTVTIGANVSALRGSSITLTCTAEGLPVPAVVWKKGGA--------TLQQGGRAFTLS 218

Query: 71  ATHGRVHSDAGVYWCEATNSYGTARSRNA-TLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
           +T     +D+G Y C ATN  GTA + +A T+H  +       +P   +   G    + C
Sbjct: 219 STES---ADSGRYDCVATNLKGTAMASSAVTIHGTL------GDPHLGRKVGGTRTSISC 269

Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
            P  G P P + W +NG++++  G  +   +DG  L++ + ++ D G Y+C+A N  G
Sbjct: 270 -PATGFPNPLIRWSRNGESVVPGGHLK---IDGSKLLLTNPQKEDNGVYKCLASNPGG 323



 Score = 68.1 bits (159), Expect = 1e-09
 Identities = 73/270 (27%), Positives = 100/270 (37%), Gaps = 26/270 (9%)

Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAE 275
           G+ +  QC   G PLP   W  S  G  +  G    L    L +  V   D G+Y C A 
Sbjct: 3   GAKLVLQCPSTGVPLPSTSW--SLNGEPLEKGGRADLRGTELVIPAVAGVDSGKYQCTAS 60

Query: 276 NSVGAVS-ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334
           N +   S AS  L   DP  + +  + V   +G      C   G P P + W+  G    
Sbjct: 61  NVIALDSRASDSLKSRDPVIVTIG-DKVETLTGTEVSIICPVEGLPPPKVTWAKNG---- 115

Query: 335 IFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394
             P  S DK+      D   V         DS     C AVN  G      +  V +   
Sbjct: 116 --PIASGDKFTIARSTD--LVFNSGKASVFDS-GRYSCRAVNNLGQDTAYSEFIVNATF- 169

Query: 395 RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVL 454
                +T G +   L   S+ +  CTA   P P + W   G  L Q  R          L
Sbjct: 170 ----TVTIGANVSALRGSSITL-TCTAEGLPVPAVVWKKGGATLQQGGR-------AFTL 217

Query: 455 KDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
              + +DSG Y CVA++  G  + S A+ +
Sbjct: 218 SSTESADSGRYDCVATNLKGTAMASSAVTI 247


>UniRef50_A7SSL0 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 270

 Score =  109 bits (262), Expect = 5e-22
 Identities = 83/285 (29%), Positives = 127/285 (44%), Gaps = 26/285 (9%)

Query: 30  TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
           TL C A G P P I+WYKG  LVV D  R    + G   + A      SD G Y C A N
Sbjct: 12  TLECLATGYPPPKIQWYKGRELVVPD-RRIATSSRGHLVINAIQ---QSDTGYYTCVAVN 67

Query: 90  SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
              TA S + ++  +V + +  + P+       D   ++CL   G P P V W K+ + L
Sbjct: 68  ---TAGSDSVSVSFSVDQTDVFVFPD-------DNSAVQCLGV-GIPPPVVTWYKDDKPL 116

Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
              G  R++    G L+I  A   D+G Y C+AR++AG+  +A+  + + + P ++  P 
Sbjct: 117 GVGG--RVYSTTQGELIISRATPEDSGTYSCVARSSAGS-VTAVVQVSVGVPPAILKRPS 173

Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGE 269
           D+    G  +  +C   G P P V W+ +  G N+     +++      + +    D G 
Sbjct: 174 DIAVNMGDVIRLECVFQGVPTPRVTWQHN--GRNLQYMTPRLV------IRDARPQDAGL 225

Query: 270 YSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
           Y C   N  G  SA   +TV   P I   P    +  G     +C
Sbjct: 226 YRCTGTNLAGRASAETSVTVRITPKIIQPPTDRTLNEGETLILSC 270



 Score = 98.3 bits (234), Expect = 1e-18
 Identities = 72/212 (33%), Positives = 102/212 (48%), Gaps = 19/212 (8%)

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
           GD++ LECL   G P P + W K G+ L+   D R+     G+LVI   +Q+D G Y C+
Sbjct: 8   GDSITLECLAT-GYPPPKIQWYK-GRELVVP-DRRIATSSRGHLVINAIQQSDTGYYTCV 64

Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
           A N AG+ +S   +  +      +  P+D      S+V  QC   G P P V W +    
Sbjct: 65  AVNTAGS-DSVSVSFSVDQTDVFVF-PDD-----NSAV--QCLGVGIPPPVVTWYKD--- 112

Query: 242 GNMPLG---RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
            + PLG   RV     G L +      D G YSC A +S G+V+A   ++V  PP+I   
Sbjct: 113 -DKPLGVGGRVYSTTQGELIISRATPEDSGTYSCVARSSAGSVTAVVQVSVGVPPAILKR 171

Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
           P+ + V  G+V R  C   G P P + W   G
Sbjct: 172 PSDIAVNMGDVIRLECVFQGVPTPRVTWQHNG 203



 Score = 78.6 bits (185), Expect = 1e-12
 Identities = 64/205 (31%), Positives = 87/205 (42%), Gaps = 19/205 (9%)

Query: 20  DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
           DV V     + + C   G P P + WYK    +           G L   RAT      D
Sbjct: 84  DVFVFPDDNSAVQCLGVGIPPPVVTWYKDDKPLGVGGRVYSTTQGELIISRAT----PED 139

Query: 80  AGVYWCEATNSYGTARSRNATLHVAV-LREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
           +G Y C A +S G   S  A + V+V +       P       GD + LEC+  +G P P
Sbjct: 140 SGTYSCVARSSAG---SVTAVVQVSVGVPPAILKRPSDIAVNMGDVIRLECV-FQGVPTP 195

Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
            V W+ NG+ L +             LVI+DAR  DAG Y+C   N AG R SA  ++ +
Sbjct: 196 RVTWQHNGRNLQYMTP---------RLVIRDARPQDAGLYRCTGTNLAG-RASAETSVTV 245

Query: 199 HIKPYLITGPEDVVAQTGSSVTFQC 223
            I P +I  P D     G ++   C
Sbjct: 246 RITPKIIQPPTDRTLNEGETLILSC 270



 Score = 56.8 bits (131), Expect = 3e-06
 Identities = 65/267 (24%), Positives = 103/267 (38%), Gaps = 31/267 (11%)

Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268
           +D  A+ G S+T +C   G P P + W +      +P  R+     G L ++ +  +D G
Sbjct: 1   KDRSARIGDSITLECLATGYPPPKIQWYKGR-ELVVPDRRIATSSRGHLVINAIQQSDTG 59

Query: 269 EYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328
            Y+C A N+ G+ S S         S ++    V V   + +   C   G P P + W  
Sbjct: 60  YYTCVAVNTAGSDSVS--------VSFSVDQTDVFVFPDDNSAVQCLGVGIPPPVVTWYK 111

Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT 388
           +        G+    Y  T        L I+     DS  T  C A + AGS     +++
Sbjct: 112 DDKPL----GVGGRVYSTTQ-----GELIISRATPEDS-GTYSCVARSSAGSVTAVVQVS 161

Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN 448
           V       PP I   PS+  + +  +    C     P P + W   G  L     R    
Sbjct: 162 V-----GVPPAILKRPSDIAVNMGDVIRLECVFQGVPTPRVTWQHNGRNLQYMTPR---- 212

Query: 449 DGTLVLKDLDKSDSGTYTCVASSRHGK 475
              LV++D    D+G Y C  ++  G+
Sbjct: 213 ---LVIRDARPQDAGLYRCTGTNLAGR 236



 Score = 44.8 bits (101), Expect = 0.015
 Identities = 24/67 (35%), Positives = 35/67 (52%)

Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVW 478
           C A   P P I WY   E ++ + R   ++ G LV+  + +SD+G YTCVA +  G    
Sbjct: 15  CLATGYPPPKIQWYKGRELVVPDRRIATSSRGHLVINAIQQSDTGYYTCVAVNTAGSDSV 74

Query: 479 SGALLVD 485
           S +  VD
Sbjct: 75  SVSFSVD 81


>UniRef50_UPI0000E4617C Cluster: PREDICTED: similar to novel
           immunoglobulin domain containing protein; n=2;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           novel immunoglobulin domain containing protein -
           Strongylocentrotus purpuratus
          Length = 2128

 Score =  109 bits (261), Expect = 6e-22
 Identities = 91/339 (26%), Positives = 135/339 (39%), Gaps = 17/339 (5%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
           V  G   +I   P  V    +  A+L C+  G P P I+WY+ G L+ S++ R  L    
Sbjct: 135 VILGPPKFISTPPDHVVFQENAEASLQCQGSGVPFPTIKWYRQGELITSNS-RITLSGDT 193

Query: 66  LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
           +   R   G    D G Y C A NS G+    N T  V        + P+      G + 
Sbjct: 194 ITIKRVVRG----DVGTYSCVAENSEGSV--INDTRFVVEGPPYIFVPPQDTSVTLGQSA 247

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLL-FDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIA 182
            L C            W   G  +   +   R   V    G L+I+   + D G Y C  
Sbjct: 248 TLSCEALSSPDNLTQQWFYEGLLVQNVEQLQRRVTVSAPLGELLIRGTERGDRGTYSCTP 307

Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP-LPDVLWRRSAGG 241
            N  GT  +A A L +     +++ P +V A  G      C    +P L   +WR+    
Sbjct: 308 TNGLGTPPTASAFLDVQYAAQVVSMPTEVYATRGEDAIIPCNTSANPALLYAIWRKDEAE 367

Query: 242 GNM-PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV--SASGYLTVYDPPSINLS 298
             +    R  + ++GSL L    L D+G Y+C   N +G    S    L V DPP  ++ 
Sbjct: 368 LRITQTNRYSITEEGSLVLGVATLNDQGSYTCTPYNDLGTAGQSTPTRLIVIDPPEFSIQ 427

Query: 299 PNSVNVES-GNVARFTCTAT-GRPEPTMFW-SVEGNRTI 334
           P  +  +S  +     CTAT    + T+ W  V G+ +I
Sbjct: 428 PEPMYEKSVDDSVSMPCTATESAVDTTLTWRKVNGDLSI 466



 Score =  103 bits (247), Expect = 3e-20
 Identities = 117/460 (25%), Positives = 193/460 (41%), Gaps = 55/460 (11%)

Query: 118 QSAQGDTVVLECLPPRGSPEPN-------VYWKKNGQT----LLFDGDS---------RM 157
           ++  GDTV+L C     +P P+       + W++   +    +LFD            R+
Sbjct: 32  EARDGDTVILPCDRVLPTPPPDFPVALFILQWQRQDISQPFFVLFDSSDAIISPAFQGRV 91

Query: 158 HLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATLK--IHIKP--YLITGPEDVV 212
             VD G +L +      DAG Y+C     +        T    + + P  ++ T P+ VV
Sbjct: 92  SQVDSGASLAMTGVTVDDAGIYECQIIELSDLESIGNGTFVNLVILGPPKFISTPPDHVV 151

Query: 213 AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV-LDDGSLRLDNVILADEGEYS 271
            Q  +  + QC+  G P P + W R    G +     ++ L   ++ +  V+  D G YS
Sbjct: 152 FQENAEASLQCQGSGVPFPTIKWYRQ---GELITSNSRITLSGDTITIKRVVRGDVGTYS 208

Query: 272 CEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEP-TMFWSVEG 330
           C AENS G+V       V  PP I + P   +V  G  A  +C A   P+  T  W  EG
Sbjct: 209 CVAENSEGSVINDTRFVVEGPPYIFVPPQDTSVTLGQSATLSCEALSSPDNLTQQWFYEG 268

Query: 331 NRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT 390
              ++   + + +   T V   +  L I  T++ D R T  C+  N  G+          
Sbjct: 269 ---LLVQNVEQLQRRVT-VSAPLGELLIRGTERGD-RGTYSCTPTNGLGTPPTASAFL-- 321

Query: 391 SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA---LIQNHRRNVT 447
             D +    + + P+         A+ PC     P  + A + + EA   + Q +R ++T
Sbjct: 322 --DVQYAAQVVSMPTEVYATRGEDAIIPCNTSANPALLYAIWRKDEAELRITQTNRYSIT 379

Query: 448 NDGTLVLKDLDKSDSGTYTCVASS---RHGKYVWSGALLVDSP---INPNIHFFRAADVS 501
            +G+LVL     +D G+YTC   +     G+   +  +++D P   I P   + ++ D  
Sbjct: 380 EEGSLVLGVATLNDQGSYTCTPYNDLGTAGQSTPTRLIVIDPPEFSIQPEPMYEKSVD-D 438

Query: 502 SLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541
           S+  P T   T +  DT  TL+W + N  G  SI  +  E
Sbjct: 439 SVSMPCT--ATESAVDT--TLTWRKVN--GDLSIRAFITE 472



 Score = 81.4 bits (192), Expect = 1e-13
 Identities = 107/437 (24%), Positives = 172/437 (39%), Gaps = 40/437 (9%)

Query: 71  ATHGRVHSDAGVYWCEATNSYGTARSRNAT-LHVAVLREE--FRLEPESKQSAQGDTVVL 127
           A  G    DAG+Y C+           N T +++ +L         P+     +     L
Sbjct: 101 AMTGVTVDDAGIYECQIIELSDLESIGNGTFVNLVILGPPKFISTPPDHVVFQENAEASL 160

Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
           +C    G P P + W + G+  L   +SR+ L  G  + I+   + D G Y C+A N+ G
Sbjct: 161 QC-QGSGVPFPTIKWYRQGE--LITSNSRITL-SGDTITIKRVVRGDVGTYSCVAENSEG 216

Query: 188 TRESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
              S I   +  ++  PY+   P+D     G S T  C     P  D L ++    G + 
Sbjct: 217 ---SVINDTRFVVEGPPYIFVPPQDTSVTLGQSATLSCEALSSP--DNLTQQWFYEGLLV 271

Query: 246 LG------RVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAV-SASGYLTVYDPPSINL 297
                   RV V    G L +      D G YSC   N +G   +AS +L V     +  
Sbjct: 272 QNVEQLQRRVTVSAPLGELLIRGTERGDRGTYSCTPTNGLGTPPTASAFLDVQYAAQVVS 331

Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
            P  V    G  A   C  +  P   + +++             ++Y  T   +G  VL 
Sbjct: 332 MPTEVYATRGEDAIIPCNTSANP--ALLYAIWRKDEAELRITQTNRYSITE--EGSLVLG 387

Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ-TLPIKSMAV 416
           +     ND + +  C+  N  G++   G+ T T      PP  +  P       +     
Sbjct: 388 V--ATLND-QGSYTCTPYNDLGTA---GQSTPTRLIVIDPPEFSIQPEPMYEKSVDDSVS 441

Query: 417 FPCTAI-CTPEPIIAWY-FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
            PCTA     +  + W    G+  I   R  +T +G  ++K + K D GTY C+A+++  
Sbjct: 442 MPCTATESAVDTTLTWRKVNGDLSI---RAFITENGLDIMK-ISKEDHGTYECMATNQVA 497

Query: 475 KYVWSGALLVDSPINPN 491
             + S  L+V SP +P+
Sbjct: 498 TVIASADLIV-SPTSPH 513



 Score = 64.5 bits (150), Expect = 2e-08
 Identities = 58/216 (26%), Positives = 91/216 (42%), Gaps = 18/216 (8%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIR-WYKGGV-LVVSDTHR-SILPAGGLF 67
           A  ++  P +V   R + A + C    +P+     W K    L ++ T+R SI   G L 
Sbjct: 326 AAQVVSMPTEVYATRGEDAIIPCNTSANPALLYAIWRKDEAELRITQTNRYSITEEGSLV 385

Query: 68  FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK-QSAQGDTVV 126
              AT     +D G Y C   N  GTA     T  + +   EF ++PE   + +  D+V 
Sbjct: 386 LGVATL----NDQGSYTCTPYNDLGTAGQSTPTRLIVIDPPEFSIQPEPMYEKSVDDSVS 441

Query: 127 LECLPPRGSPEPNVYWKK-NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
           + C     + +  + W+K NG     D   R  + + G L I    + D G Y+C+A N 
Sbjct: 442 MPCTATESAVDTTLTWRKVNG-----DLSIRAFITENG-LDIMKISKEDHGTYECMATNQ 495

Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTF 221
             T    IA+  + + P     P DV   T S+  +
Sbjct: 496 VAT---VIASADLIVSPTSPHTPTDVAVVTSSTSAY 528


>UniRef50_UPI0000DB6E73 Cluster: PREDICTED: similar to CG31190-PB,
           isoform B, partial; n=2; Apocrita|Rep: PREDICTED:
           similar to CG31190-PB, isoform B, partial - Apis
           mellifera
          Length = 1985

 Score =  109 bits (261), Expect = 6e-22
 Identities = 95/351 (27%), Positives = 145/351 (41%), Gaps = 26/351 (7%)

Query: 4   DYVTSGEAP-YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG----GVLVVSDTHR 58
           + V   + P +++E P  +  +    + L+C A GSP+P + W        V  V    R
Sbjct: 4   ELVVGQQGPVFVLEPPSTLVFSNTTGSQLSCSAHGSPTPHVTWITSPDQRSVTAVPGL-R 62

Query: 59  SILPAGGLFF--LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPES 116
            +L  G L+F    A   R       Y C AT+S GT  SR  TL   +    + +    
Sbjct: 63  QLLGNGTLYFPPFLAQDFRAEVHNARYRCRATSSVGTVLSREVTLRAVLTVPGYDVRVNR 122

Query: 117 KQSAQGDTVVLECLPPRGSPEPNVY--WKKNGQTLL---FDGDSRMHLVDGGNLVIQDAR 171
               +G   VL C       E      W ++   LL    D   R  +   G+L I+ AR
Sbjct: 123 SPVLEGCNAVLSCTAREDVKEHLTVTSWFRDDAILLPGSTDTGGRFVVTSQGDLHIRAAR 182

Query: 172 QTDA-GRYQCIARNA--AGTRESAIATLKIH-----IKPYLITGPEDVV-AQTGSSVTFQ 222
             D    Y C+  +A     R S  ATL +      + P L+   +  + A++GS V   
Sbjct: 183 PDDGRATYSCLTFHALTGERRRSEPATLTVTEPTGTMPPRLMQRSQIAISAESGSDVHLT 242

Query: 223 CRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279
           C   G+P P   W R   G ++P+   GR+++  D  +++  V   D G Y C A N VG
Sbjct: 243 CSAQGNPAPQFAWYRDVNGHSIPVESFGRIQLWGD-LMQIRRVDAQDAGRYICRASNQVG 301

Query: 280 AVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
              A  +L+V    +  + P    + SG  A   CT  G P  ++ W  +G
Sbjct: 302 EQRAETHLSVTSKLNARIQPRVQIINSGESATMNCTVEGYPVESVEWLHDG 352



 Score =  103 bits (247), Expect = 3e-20
 Identities = 97/380 (25%), Positives = 151/380 (39%), Gaps = 24/380 (6%)

Query: 30  TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
           T+ C   G P  ++ W +GGV +  D    +   G L           +DAG Y C    
Sbjct: 550 TIACPYSGYPITSVEWSRGGVALPLDIRHRVDSEGHLTIANVD----PNDAGTYTCMVRA 605

Query: 90  SYGTARSRNATLHVA--VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
             G   SR+  L V+   +   F   P + Q  +G    + C    G       W K+G+
Sbjct: 606 RSGETASRDIRLTVSSPPIMTPFNF-PSNLQ--EGSRAQVTCTVTSGDLPIYFSWLKDGE 662

Query: 148 TLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT 206
            L         + +  + LV ++     +G+Y C+A N+A  + +  A L + + P  I 
Sbjct: 663 PLPSSLRIEERVAEFFSLLVFKELSSRHSGKYTCVATNSA-AKVNHTAELLVKVPPQWIF 721

Query: 207 GPEDVVAQTGSSVTFQCRVGGDPLPDVLW---RRSAGGGNMPL-----GRVKVLDDGSLR 258
            P+DV    G+ +   C   G P P V W   R        PL     GR+ +L +GSL 
Sbjct: 722 EPQDVATLLGNPLNVHCEAKGFPPPRVTWLRARERTSNDYQPLIDGTDGRLTILPNGSLW 781

Query: 259 LDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
             +    DEG Y C A N +G+ +S   Y++V++P        +V +  G      CT  
Sbjct: 782 TASAGPQDEGHYLCRANNGIGSGLSKVIYVSVHEPARFEFQSKNVTIRRGESVTLDCTVI 841

Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV-TVLTINDTDKNDSRNTIVCSAVN 376
           G     + W    +R  +     R         +G+ + L+I  +D+ DS     C+A N
Sbjct: 842 GDNPIEVQWMHNSDR--LDTNNHRLSISQIKTDNGLKSQLSIGSSDRQDS-GVYRCTADN 898

Query: 377 YAGSSFVRGKLTVTSDDDRP 396
             G S     L V    D P
Sbjct: 899 AYGRSEHLIYLAVQERPDPP 918



 Score = 83.0 bits (196), Expect = 4e-14
 Identities = 105/412 (25%), Positives = 160/412 (38%), Gaps = 30/412 (7%)

Query: 79  DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
           D G+Y C A N+  T   + A L++        + P   ++  G    + C P  G P  
Sbjct: 506 DGGLYACVAANTLATVEHK-ARLNIYGPPYIRSIGPV--RAIAGVDTTIAC-PYSGYPIT 561

Query: 139 NVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
           +V W + G  L  D     H VD  G+L I +    DAG Y C+ R  +G   S    L 
Sbjct: 562 SVEWSRGGVALPLD---IRHRVDSEGHLTIANVDPNDAGTYTCMVRARSGETASRDIRLT 618

Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RV--KVLDD 254
           +   P +         Q GS     C V    LP + +     G  +P   R+  +V + 
Sbjct: 619 VSSPPIMTPFNFPSNLQEGSRAQVTCTVTSGDLP-IYFSWLKDGEPLPSSLRIEERVAEF 677

Query: 255 GSLRLDNVILA-DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313
            SL +   + +   G+Y+C A NS   V+ +  L V  PP     P  V    GN     
Sbjct: 678 FSLLVFKELSSRHSGKYTCVATNSAAKVNHTAELLVKVPPQWIFEPQDVATLLGNPLNVH 737

Query: 314 CTATGRPEPTMFWSVEGNRTI--IFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371
           C A G P P + W     RT     P +       T + +G ++ T +   +++     +
Sbjct: 738 CEAKGFPPPRVTWLRARERTSNDYQPLIDGTDGRLTILPNG-SLWTASAGPQDEGH--YL 794

Query: 372 CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431
           C A N  GS     K+   S  +  P        N T+         CT I      + W
Sbjct: 795 CRANNGIGSGL--SKVIYVSVHE--PARFEFQSKNVTIRRGESVTLDCTVIGDNPIEVQW 850

Query: 432 YFEGEAL-IQNHRRNV----TNDGT---LVLKDLDKSDSGTYTCVASSRHGK 475
               + L   NHR ++    T++G    L +   D+ DSG Y C A + +G+
Sbjct: 851 MHNSDRLDTNNHRLSISQIKTDNGLKSQLSIGSSDRQDSGVYRCTADNAYGR 902



 Score = 82.2 bits (194), Expect = 8e-14
 Identities = 110/472 (23%), Positives = 183/472 (38%), Gaps = 53/472 (11%)

Query: 45  WYKGGVLVV---SDTH-RSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNAT 100
           W++   +++   +DT  R ++ + G   +RA   R       Y C   ++    R R+  
Sbjct: 150 WFRDDAILLPGSTDTGGRFVVTSQGDLHIRAA--RPDDGRATYSCLTFHALTGERRRSEP 207

Query: 101 LHVAVLREEFRLEPESKQSAQ-------GDTVVLECLPPRGSPEPNVYWKK--NGQTLLF 151
             + V      + P   Q +Q       G  V L C   +G+P P   W +  NG ++  
Sbjct: 208 ATLTVTEPTGTMPPRLMQRSQIAISAESGSDVHLTC-SAQGNPAPQFAWYRDVNGHSIPV 266

Query: 152 DGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDV 211
           +   R+ L  G  + I+     DAGRY C A N  G  + A   L +  K      P   
Sbjct: 267 ESFGRIQLW-GDLMQIRRVDAQDAGRYICRASNQVG-EQRAETHLSVTSKLNARIQPRVQ 324

Query: 212 VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNVILADEGEY 270
           +  +G S T  C V G P+  V W             R+++L    L + +V   D+G Y
Sbjct: 325 IINSGESATMNCTVEGYPVESVEWLHDGVPVLTAQDTRIRLLAPLVLVIGSVGRKDKGMY 384

Query: 271 SCEAENSVGAVSASGYLTVYDP-PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWS-- 327
            C   +      A+  L + D  P +  +     +  G      C+ATG P P+  W   
Sbjct: 385 QCLVRSDKENAQATAELKLGDTVPELQYTFIEQALRPGPPVSLRCSATGSPPPSFTWLLD 444

Query: 328 -------------VEGNRTIIFPGMSRDKY------HATAVF-----DGVTVLTINDTDK 363
                        V G+ +I  P ++R         +A   +     D ++ L I+    
Sbjct: 445 GEPLSEIASGHRFVSGSPSINNPLLNRCTMAGWLYRYAIGQYVDQSGDVISHLNISSAGA 504

Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
            D      C A N   +   + +L +      PP I + GP      + +    P +   
Sbjct: 505 EDG-GLYACVAANTLATVEHKARLNIYG----PPYIRSIGPVRAIAGVDTTIACPYSGY- 558

Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
            P   + W   G AL  + R  V ++G L + ++D +D+GTYTC+  +R G+
Sbjct: 559 -PITSVEWSRGGVALPLDIRHRVDSEGHLTIANVDPNDAGTYTCMVRARSGE 609



 Score = 78.2 bits (184), Expect = 1e-12
 Identities = 98/378 (25%), Positives = 143/378 (37%), Gaps = 32/378 (8%)

Query: 164 NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT-GPEDVVAQTGSSVTFQ 222
           +L I  A   D G Y C+A N   T E   A L I+  PY+ + GP   +A  G   T  
Sbjct: 496 HLNISSAGAEDGGLYACVAANTLATVEHK-ARLNIYGPPYIRSIGPVRAIA--GVDTTIA 552

Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281
           C   G P+  V W R  GG  +PL  R +V  +G L + NV   D G Y+C      G  
Sbjct: 553 CPYSGYPITSVEWSR--GGVALPLDIRHRVDSEGHLTIANVDPNDAGTYTCMVRARSGET 610

Query: 282 SASGY-LTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF-WSVEGNRTIIFPGM 339
           ++    LTV  PP +       N++ G+ A+ TCT T    P  F W  +G      P  
Sbjct: 611 ASRDIRLTVSSPPIMTPFNFPSNLQEGSRAQVTCTVTSGDLPIYFSWLKDGEP---LPSS 667

Query: 340 SRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPI 399
            R +      F   ++L   +     S     C A N A       +L V      PP  
Sbjct: 668 LRIEERVAEFF---SLLVFKELSSRHS-GKYTCVATNSAAKVNHTAELLVKV----PPQW 719

Query: 400 ITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH---------RRNVTNDG 450
           I       TL    + V  C A   P P + W    E    ++         R  +  +G
Sbjct: 720 IFEPQDVATLLGNPLNVH-CEAKGFPPPRVTWLRARERTSNDYQPLIDGTDGRLTILPNG 778

Query: 451 TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKP 510
           +L        D G Y C A++  G  +    ++  S   P    F++ +V+   G     
Sbjct: 779 SLWTASAGPQDEGHYLCRANNGIGSGL--SKVIYVSVHEPARFEFQSKNVTIRRGESVTL 836

Query: 511 ITHNVTDTSVTLSWSQNN 528
               + D  + + W  N+
Sbjct: 837 DCTVIGDNPIEVQWMHNS 854



 Score = 77.4 bits (182), Expect = 2e-12
 Identities = 67/245 (27%), Positives = 104/245 (42%), Gaps = 19/245 (7%)

Query: 80  AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
           +G Y C ATNS     +  A L V V   ++  EP+   +  G+ + + C   +G P P 
Sbjct: 691 SGKYTCVATNSAAKV-NHTAELLVKV-PPQWIFEPQDVATLLGNPLNVHC-EAKGFPPPR 747

Query: 140 VYWKK------NGQTLLFDG-DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
           V W +      N    L DG D R+ ++  G+L    A   D G Y C A N  G+  S 
Sbjct: 748 VTWLRARERTSNDYQPLIDGTDGRLTILPNGSLWTASAGPQDEGHYLCRANNGIGSGLSK 807

Query: 193 IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW-----RRSAGGGNMPLG 247
           +  + +H         ++V  + G SVT  C V GD   +V W     R       + + 
Sbjct: 808 VIYVSVHEPARFEFQSKNVTIRRGESVTLDCTVIGDNPIEVQWMHNSDRLDTNNHRLSIS 867

Query: 248 RVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
           ++K  D+G    L + +    D G Y C A+N+ G      YL V + P    S   + +
Sbjct: 868 QIKT-DNGLKSQLSIGSSDRQDSGVYRCTADNAYGRSEHLIYLAVQERPDPPASLEVIEI 926

Query: 305 ESGNV 309
            S ++
Sbjct: 927 GSRSI 931



 Score = 76.2 bits (179), Expect = 5e-12
 Identities = 60/211 (28%), Positives = 96/211 (45%), Gaps = 16/211 (7%)

Query: 31  LNCRAGGSPSPAIRWYK--GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
           L C A G+P+P   WY+   G  +  ++   I   G L  +R    +   DAG Y C A+
Sbjct: 241 LTCSAQGNPAPQFAWYRDVNGHSIPVESFGRIQLWGDLMQIRRVDAQ---DAGRYICRAS 297

Query: 89  NSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
           N  G  R   A  H++V  +   R++P  +    G++  + C    G P  +V W  +G 
Sbjct: 298 NQVGEQR---AETHLSVTSKLNARIQPRVQIINSGESATMNCTV-EGYPVESVEWLHDGV 353

Query: 148 TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI---KPYL 204
            +L   D+R+ L+    LVI    + D G YQC+ R+    +E+A AT ++ +    P L
Sbjct: 354 PVLTAQDTRIRLLAPLVLVIGSVGRKDKGMYQCLVRS---DKENAQATAELKLGDTVPEL 410

Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
                +   + G  V+ +C   G P P   W
Sbjct: 411 QYTFIEQALRPGPPVSLRCSATGSPPPSFTW 441



 Score = 62.1 bits (144), Expect = 9e-08
 Identities = 39/136 (28%), Positives = 65/136 (47%), Gaps = 4/136 (2%)

Query: 693  EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKW 752
            ++T LRK+TKY+  +  F     G  S   V  T + VP+ PP  +    L++ +V + W
Sbjct: 1110 QLTGLRKFTKYDISIRAFNSIASGPASVPIVGTTQEGVPETPPTQVTCVPLSSQSVKVSW 1169

Query: 753  SPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSL--IMTNLTSGVSYSVQI 810
            S P      GII GY V   +  VP +   ++    V + +S+   +  L    +YS+++
Sbjct: 1170 SAPPPHQHGGIIQGYKVY--YRPVPTDNMDISTVREVKKTSSVETYLHTLYKYTNYSIRV 1227

Query: 811  AAETIIGLGPFSQKVY 826
             A T  G G  S  ++
Sbjct: 1228 LAYTGAGDGVLSPPIF 1243



 Score = 58.0 bits (134), Expect = 1e-06
 Identities = 58/200 (29%), Positives = 86/200 (43%), Gaps = 27/200 (13%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG---------GVLVVSDTHRSILP 62
           P  I +P DV      P  ++C A G P P + W +           ++  +D   +ILP
Sbjct: 717 PQWIFEPQDVATLLGNPLNVHCEAKGFPPPRVTWLRARERTSNDYQPLIDGTDGRLTILP 776

Query: 63  AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-- 120
            G L+    T      D G Y C A N  G+  S+   ++V+V  E  R E +SK     
Sbjct: 777 NGSLW----TASAGPQDEGHYLCRANNGIGSGLSK--VIYVSV-HEPARFEFQSKNVTIR 829

Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL----VDGG---NLVIQDARQT 173
           +G++V L+C     +P   V W  N    L   + R+ +     D G    L I  + + 
Sbjct: 830 RGESVTLDCTVIGDNP-IEVQWMHNSDR-LDTNNHRLSISQIKTDNGLKSQLSIGSSDRQ 887

Query: 174 DAGRYQCIARNAAGTRESAI 193
           D+G Y+C A NA G  E  I
Sbjct: 888 DSGVYRCTADNAYGRSEHLI 907



 Score = 56.8 bits (131), Expect = 3e-06
 Identities = 57/223 (25%), Positives = 90/223 (40%), Gaps = 30/223 (13%)

Query: 411  IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470
            IKS     C  +  P P   W +    +       +T DG L ++ L++S +G YTC AS
Sbjct: 1367 IKSSITLSCLVVGNPTPRPIWTYRNSQISTGRHYELTADGHLNIRGLEQSVAGNYTCSAS 1426

Query: 471  SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530
            +  G    +  L+V  P                P  P   + +  T+ S+   W+  N  
Sbjct: 1427 NLFGDDSITYTLVVVMP----------------PRAPILELQYTTTN-SIRFRWNHPNN- 1468

Query: 531  GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590
            G ++I GY   V S +        R+  GW  IA    QT +++  L  G +Y+  +   
Sbjct: 1469 GGATIQGY---VLSYK--------RDQGGWEEIALSPEQTEFILSGLKCGSSYLAHLTAH 1517

Query: 591  NSHGLSGPSPVSDSVTVGDDSNSLWEGTGVS-NSTEYRNNILT 632
            N  G   PS +  + T G       E   +S N T  + N+L+
Sbjct: 1518 NRVGTGDPSSLISATTKGTAPLLPKERDIISANGTSVKLNLLS 1560



 Score = 52.0 bits (119), Expect = 1e-04
 Identities = 37/137 (27%), Positives = 69/137 (50%), Gaps = 11/137 (8%)

Query: 639  IEATPIDSKTIKLMWEILNFYY----LEGLFIYFRPL--DNITIEYEMKTILHSNDVSGF 692
            +   P+ S+++K+ W     +     ++G  +Y+RP+  DN+ I   ++ +  ++ V  +
Sbjct: 1155 VTCVPLSSQSVKVSWSAPPPHQHGGIIQGYKVYYRPVPTDNMDIS-TVREVKKTSSVETY 1213

Query: 693  EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKW 752
             + +L KYT Y   ++ +    +G  S      T +DVP GPP  I+   L   ++ + W
Sbjct: 1214 -LHTLYKYTNYSIRVLAYTGAGDGVLSPPIFCTTEEDVP-GPPAGIKALALTAESILVSW 1271

Query: 753  SPPELQLQNGIITGYNV 769
             PP LQ  NG ++ Y V
Sbjct: 1272 LPP-LQ-PNGNVSKYTV 1286



 Score = 50.8 bits (116), Expect = 2e-04
 Identities = 72/308 (23%), Positives = 114/308 (37%), Gaps = 20/308 (6%)

Query: 203 YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL--GRVKVLDDGSLRLD 260
           +++  P  +V    +     C   G P P V W  S    ++    G  ++L +G+L   
Sbjct: 14  FVLEPPSTLVFSNTTGSQLSCSAHGSPTPHVTWITSPDQRSVTAVPGLRQLLGNGTLYFP 73

Query: 261 NVILAD------EGEYSCEAENSVGAVSASGYL--TVYDPPSINLSPNSVNVESGNVARF 312
             +  D         Y C A +SVG V +       V   P  ++  N   V  G  A  
Sbjct: 74  PFLAQDFRAEVHNARYRCRATSSVGTVLSREVTLRAVLTVPGYDVRVNRSPVLEGCNAVL 133

Query: 313 TCTATGR-PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371
           +CTA     E     S   +  I+ PG +           G   L I     +D R T  
Sbjct: 134 SCTAREDVKEHLTVTSWFRDDAILLPGSTDTGGRFVVTSQGD--LHIRAARPDDGRATYS 191

Query: 372 CSAVNYAGSSFVRGK---LTVTSDDDRPPP-IITNGPSNQTLPIKSMAVFPCTAICTPEP 427
           C   +       R +   LTVT      PP ++       +    S     C+A   P P
Sbjct: 192 CLTFHALTGERRRSEPATLTVTEPTGTMPPRLMQRSQIAISAESGSDVHLTCSAQGNPAP 251

Query: 428 IIAWYFE--GEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
             AWY +  G ++ +++  R       + ++ +D  D+G Y C AS++ G+      L V
Sbjct: 252 QFAWYRDVNGHSIPVESFGRIQLWGDLMQIRRVDAQDAGRYICRASNQVGEQRAETHLSV 311

Query: 485 DSPINPNI 492
            S +N  I
Sbjct: 312 TSKLNARI 319



 Score = 47.2 bits (107), Expect = 0.003
 Identities = 32/109 (29%), Positives = 53/109 (48%), Gaps = 6/109 (5%)

Query: 718  PSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVP 777
            P++  VA+T ++ P  PP NI++       + + W PP  +  NG + GY  +V W +  
Sbjct: 1030 PTDPVVAKTQEEAPTEPPQNIKVQSAGPGELMVSWQPPPKESCNGDLLGY--IVTWSEHS 1087

Query: 778  ANKSMV--AINTTVH--QATSLIMTNLTSGVSYSVQIAAETIIGLGPFS 822
            ++ S V  + + TV+    T + +T L     Y + I A   I  GP S
Sbjct: 1088 SSTSGVNQSKSLTVNGWATTKVQLTGLRKFTKYDISIRAFNSIASGPAS 1136



 Score = 43.2 bits (97), Expect = 0.044
 Identities = 35/133 (26%), Positives = 54/133 (40%), Gaps = 4/133 (3%)

Query: 17  QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV 76
           QP    +   + AT+NC   G P  ++ W   GV V++     I     L  +  + GR 
Sbjct: 320 QPRVQIINSGESATMNCTVEGYPVESVEWLHDGVPVLTAQDTRIRLLAPLVLVIGSVGR- 378

Query: 77  HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
             D G+Y C   +    A++  A L +     E +     +    G  V L C    GSP
Sbjct: 379 -KDKGMYQCLVRSDKENAQA-TAELKLGDTVPELQYTFIEQALRPGPPVSLRC-SATGSP 435

Query: 137 EPNVYWKKNGQTL 149
            P+  W  +G+ L
Sbjct: 436 PPSFTWLLDGEPL 448



 Score = 40.3 bits (90), Expect = 0.31
 Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 3/78 (3%)

Query: 217  SSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR-VKVLDDGSLRLDNVILADEGEYSCEAE 275
            SS+T  C V G+P P  +W  +     +  GR  ++  DG L +  +  +  G Y+C A 
Sbjct: 1369 SSITLSCLVVGNPTPRPIW--TYRNSQISTGRHYELTADGHLNIRGLEQSVAGNYTCSAS 1426

Query: 276  NSVGAVSASGYLTVYDPP 293
            N  G  S +  L V  PP
Sbjct: 1427 NLFGDDSITYTLVVVMPP 1444



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 36/132 (27%), Positives = 50/132 (37%), Gaps = 8/132 (6%)

Query: 74   GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTVVLECLP 131
            G V S    +W  AT   G              R   R+   S+  + A   ++ L CL 
Sbjct: 1318 GLVESQLYEFWVSATTGLGEGEPTTIVTQTTNTRAPARVASFSQLLRRAIKSSITLSCLV 1377

Query: 132  PRGSPEPNVYWK-KNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
              G+P P   W  +N Q           L   G+L I+   Q+ AG Y C A N  G  +
Sbjct: 1378 V-GNPTPRPIWTYRNSQ---ISTGRHYELTADGHLNIRGLEQSVAGNYTCSASNLFGD-D 1432

Query: 191  SAIATLKIHIKP 202
            S   TL + + P
Sbjct: 1433 SITYTLVVVMPP 1444



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 4/92 (4%)

Query: 5   YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR----SI 60
           YV+  E      Q  +VT+ R +  TL+C   G     ++W      + ++ HR     I
Sbjct: 810 YVSVHEPARFEFQSKNVTIRRGESVTLDCTVIGDNPIEVQWMHNSDRLDTNNHRLSISQI 869

Query: 61  LPAGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
               GL    +       D+GVY C A N+YG
Sbjct: 870 KTDNGLKSQLSIGSSDRQDSGVYRCTADNAYG 901


>UniRef50_Q4SW90 Cluster: Chromosome undetermined SCAF13667, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF13667,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 1278

 Score =  109 bits (261), Expect = 6e-22
 Identities = 134/562 (23%), Positives = 219/562 (38%), Gaps = 58/562 (10%)

Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEA 274
           G  +  +C   G P P + W R   GG++P  +VK  + + +L +  V   D GEY C A
Sbjct: 340 GQQLLLECIAAGVPTPTIKWYRK--GGDLPERKVKFENFNKTLLVVGVSEEDAGEYVCMA 397

Query: 275 ENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334
            N  G++  S  + V   P     P ++ +      R  C A G P+P + W + G    
Sbjct: 398 INHQGSIRHSILVQVKAAPYWLDKPTNLVLAPNENGRLVCRANGNPKPNIQWLINGQPIE 457

Query: 335 IFP-GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
             P   SRD    T +F  V +          S     C+A N  G       ++V    
Sbjct: 458 SSPQNPSRDVLGDTIIFRSVQM---------GSSAVYQCNASNQYGYLLSNAFVSVL--- 505

Query: 394 DRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDG 450
           D PP ++  GP NQ + +   +     C    +P P + W+  G+   +     +V N+G
Sbjct: 506 DMPPRML--GPKNQLIKVIENNHTFLDCPFFGSPLPDLRWFKNGQGSGVDGGHYSVHNNG 563

Query: 451 TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV--DSPINPNIHFFRAADVSSLPGPPT 508
           TL +K     D GTYTCVASS  GK      L V  ++ +NP++    +A     P PP 
Sbjct: 564 TLEIKRARSEDEGTYTCVASSLLGKAENQVRLEVKEEASLNPSV---SSALPPDRPDPPL 620

Query: 509 KPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVH 568
           +    +    SV L+W   N    S +  + V+        G         W  ++    
Sbjct: 621 ELDLSDPAVRSVRLTWIPGND-NRSPVTHFLVQFEEDRWEPGR--------WRNLSSYPG 671

Query: 569 QTHYVVKSLIPGITYMFIVRTENSHGLSGPS-PVSDSVTVGDDSNSLWEGTGVSNSTEYR 627
             + V+  L P + Y F V   NS G S PS P     T G   + +  G     S +  
Sbjct: 672 HLNSVILQLAPFVNYQFRVIAINSVGQSEPSLPSPQYKTSGAAPDVIPRGLRGWGSMKGN 731

Query: 628 NNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSN 687
             I  + +++L                  N YY     ++++  D  + ++   T + + 
Sbjct: 732 MEITWEPLLDLER-------------NGANLYY----SVWWKRKDT-SEDWNNVTTVRTK 773

Query: 688 DVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTT 747
            V    + +   Y  Y+  +    +   G  SN  +  + +D P   P  + +  ++T  
Sbjct: 774 HV----VHNTETYVPYQIKIQAGNEFGSGPESNIIIGYSGEDTPTDAPTELRVSRVDTNR 829

Query: 748 VHLKWSPPELQLQNGIITGYNV 769
            H+ W   +L+   G    Y V
Sbjct: 830 AHIHWKSVDLKSVQGEFKEYRV 851



 Score =   99 bits (238), Expect = 4e-19
 Identities = 76/281 (27%), Positives = 119/281 (42%), Gaps = 10/281 (3%)

Query: 23  VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
           V R Q   L C A G P+P I+WY+ G     D     +            G    DAG 
Sbjct: 337 VLRGQQLLLECIAAGVPTPTIKWYRKG----GDLPERKVKFENFNKTLLVVGVSEEDAGE 392

Query: 83  YWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSPEPNVY 141
           Y C A N  G+ R    ++ V V    + L+ P +   A  +   L C    G+P+PN+ 
Sbjct: 393 YVCMAINHQGSIRH---SILVQVKAAPYWLDKPTNLVLAPNENGRLVCRA-NGNPKPNIQ 448

Query: 142 WKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201
           W  NGQ +     +    V G  ++ +  +   +  YQC A N  G   S      + + 
Sbjct: 449 WLINGQPIESSPQNPSRDVLGDTIIFRSVQMGSSAVYQCNASNQYGYLLSNAFVSVLDMP 508

Query: 202 PYLITGPEDVVAQTGSSVTF-QCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLD 260
           P ++     ++    ++ TF  C   G PLPD+ W ++  G  +  G   V ++G+L + 
Sbjct: 509 PRMLGPKNQLIKVIENNHTFLDCPFFGSPLPDLRWFKNGQGSGVDGGHYSVHNNGTLEIK 568

Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
                DEG Y+C A + +G       L V +  S+N S +S
Sbjct: 569 RARSEDEGTYTCVASSLLGKAENQVRLEVKEEASLNPSVSS 609



 Score = 81.4 bits (192), Expect = 1e-13
 Identities = 59/188 (31%), Positives = 93/188 (49%), Gaps = 14/188 (7%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS---DTHRSILPAGGLF 67
           APY +++P ++ +A ++   L CRA G+P P I+W   G  + S   +  R +L  G   
Sbjct: 415 APYWLDKPTNLVLAPNENGRLVCRANGNPKPNIQWLINGQPIESSPQNPSRDVL--GDTI 472

Query: 68  FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTV 125
             R+        + VY C A+N YG   S NA + V  +     L P+++  +  + +  
Sbjct: 473 IFRSVQ---MGSSAVYQCNASNQYGYLLS-NAFVSVLDMPPRM-LGPKNQLIKVIENNHT 527

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
            L+C P  GSP P++ W KNGQ    DG     + + G L I+ AR  D G Y C+A + 
Sbjct: 528 FLDC-PFFGSPLPDLRWFKNGQGSGVDG-GHYSVHNNGTLEIKRARSEDEGTYTCVASSL 585

Query: 186 AGTRESAI 193
            G  E+ +
Sbjct: 586 LGKAENQV 593



 Score = 70.1 bits (164), Expect = 3e-10
 Identities = 126/523 (24%), Positives = 199/523 (38%), Gaps = 70/523 (13%)

Query: 10  EAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGL 66
           + P I++Q + D  V       + C A G+P P   W + G    +  D   +     G 
Sbjct: 1   QPPTIVKQSVKDYIVDPRDNIIIECEAKGNPVPDFSWRRNGKFFNLGKDPRVATQKDSGT 60

Query: 67  FFLRATHGRVHSD-AGVYWCEATNSYGTARSRNATL---------------HVAVLRE-- 108
             +    G    D  G Y C A+N  G A S    L               H +V+ +  
Sbjct: 61  LEINFRSGGKQEDYEGEYQCFASNELGVALSNKILLRVSSEDTLLNTCRFSHSSVVSDCF 120

Query: 109 -----EFRLEPESKQS----AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL 159
                E  L P+         +G +++L C PP G P P ++W  +  T +   D R+ +
Sbjct: 121 CATTLEAPLWPKEVLDPVLVTEGSSLILPCNPPPGLPPPLIFWMDSTMTPIVQ-DKRVSM 179

Query: 160 VDGGNLVIQDARQTDA-GRYQCIARN--AAGTRESAIATLKIHIK-PYLITGPEDVVAQT 215
              G+L   +    DA   Y+C AR       ++     LK+H K P+  T   D     
Sbjct: 180 GLNGDLYFSNVMAKDAHNEYKCNARCRLTQTIQQKNPFILKVHTKEPFNDTSHNDTDPYG 239

Query: 216 GSSVTFQCRVGG-DPL----PDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEY 270
                 + ++    PL      V   R  GG   P      LD     L N ++    E 
Sbjct: 240 EDEEDARGQISQISPLIVKRASVHPVRCCGGKERP--DQDGLDMPREGLVNKMVERYLES 297

Query: 271 SCEAEN-SVGAVSASGYLTVYDP--PSINLSP----NSVNVESGNVARFTCTATGRPEPT 323
           + +AE+   G +   G         P++ LSP    +S  V  G      C A G P PT
Sbjct: 298 NSQAEDPEEGLMDGCGRSRKLPQTMPTL-LSPTGSQSSKMVLRGQQLLLECIAAGVPTPT 356

Query: 324 MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383
           + W  +G   +    +  + ++ T +  GV+          +     VC A+N+ GS  +
Sbjct: 357 IKWYRKGG-DLPERKVKFENFNKTLLVVGVS---------EEDAGEYVCMAINHQGS--I 404

Query: 384 RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG---EALIQ 440
           R  + V     +  P   + P+N  L         C A   P+P I W   G   E+  Q
Sbjct: 405 RHSILV---QVKAAPYWLDKPTNLVLAPNENGRLVCRANGNPKPNIQWLINGQPIESSPQ 461

Query: 441 NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
           N  R+V  D T++ + +    S  Y C AS+++G Y+ S A +
Sbjct: 462 NPSRDVLGD-TIIFRSVQMGSSAVYQCNASNQYG-YLLSNAFV 502



 Score = 50.4 bits (115), Expect = 3e-04
 Identities = 34/126 (26%), Positives = 57/126 (45%), Gaps = 4/126 (3%)

Query: 694  ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
            ++ L  ++KY+ F++     +EG PSN+    T + VPD P     +   N  TVHL+W 
Sbjct: 911  LSELVPFSKYKMFMVVANTHYEGPPSNTVEFTTKEGVPDAPRF-FTINRKNVDTVHLEWG 969

Query: 754  PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAE 813
             P L+  NGI+ GY +    ++  +        T +   T   +        Y   ++A 
Sbjct: 970  KP-LE-PNGILIGYQLKYQTVN-GSTVGRAQFETFLPNVTEFTLRLPDRAARYKFYLSAV 1026

Query: 814  TIIGLG 819
            T +G G
Sbjct: 1027 TQVGSG 1032


>UniRef50_A1Z920 Cluster: CG8581-PA, isoform A; n=8; Diptera|Rep:
           CG8581-PA, isoform A - Drosophila melanogaster (Fruit
           fly)
          Length = 1526

 Score =  109 bits (261), Expect = 6e-22
 Identities = 75/259 (28%), Positives = 121/259 (46%), Gaps = 18/259 (6%)

Query: 42  AIRWYKGGVLVVSDTHRSI-LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNAT 100
           +++W K  + +  D  R + LP G L           SD G Y C  T+   +  S    
Sbjct: 179 SVQWLKDDLPLPLDKLRMVVLPNGALEIDEVGP----SDRGSYQCNVTSGSSSRLSSKTN 234

Query: 101 LHVAV---------LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLF 151
           L++           +   F + P  K   +GDTV L+C+   G P+P + W +NG  L F
Sbjct: 235 LNIKKPSDPGAENSVAPSFLVGPSPKTVREGDTVTLDCVA-NGVPKPQIKWLRNGMDLDF 293

Query: 152 -DGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED 210
            D DSR  +V  G+L I  A   D+G YQC A N   + + A AT+++   P  I  P+D
Sbjct: 294 NDLDSRFSIVGTGSLQISSAEDIDSGNYQCRASNTVDSLD-AQATVQVQEPPKFIKAPKD 352

Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEY 270
             A        +C + G P P + W ++ G    P   ++++D  +L++  ++ +D G +
Sbjct: 353 TTAHEKDEPELKCDIWGKPKPVIRWLKN-GDLITPNDYMQLVDGHNLKILGLLNSDAGMF 411

Query: 271 SCEAENSVGAVSASGYLTV 289
            C   N+ G+V A+  L V
Sbjct: 412 QCVGTNAAGSVHAAARLRV 430



 Score = 97.1 bits (231), Expect = 3e-18
 Identities = 81/314 (25%), Positives = 129/314 (41%), Gaps = 28/314 (8%)

Query: 40  SPAIRWYKG----GVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT-NSYGTA 94
           S +IRW +G     +++V DT R+ L  G L+       R     G Y C  T    G+ 
Sbjct: 75  SVSIRW-RGPDGQDLVIVGDTFRTQLKNGSLYISSVEENR--GLTGAYQCLLTAEGVGSI 131

Query: 95  RSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPEP----NVYWKKNGQTL 149
            SR A   VA++R+ +   +        G T    C+    + +     +V W K+   L
Sbjct: 132 LSRPAL--VAIVRQPDLNQDFLETYLLPGQTAYFRCMLGEANWQEGVKHSVQWLKDDLPL 189

Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH---------- 199
             D   RM ++  G L I +   +D G YQC   + + +R S+   L I           
Sbjct: 190 PLD-KLRMVVLPNGALEIDEVGPSDRGSYQCNVTSGSSSRLSSKTNLNIKKPSDPGAENS 248

Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPLGRVKVLDDGSL 257
           + P  + GP     + G +VT  C   G P P + W R+      N    R  ++  GSL
Sbjct: 249 VAPSFLVGPSPKTVREGDTVTLDCVANGVPKPQIKWLRNGMDLDFNDLDSRFSIVGTGSL 308

Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
           ++ +    D G Y C A N+V ++ A   + V +PP    +P        +     C   
Sbjct: 309 QISSAEDIDSGNYQCRASNTVDSLDAQATVQVQEPPKFIKAPKDTTAHEKDEPELKCDIW 368

Query: 318 GRPEPTMFWSVEGN 331
           G+P+P + W   G+
Sbjct: 369 GKPKPVIRWLKNGD 382



 Score = 83.8 bits (198), Expect = 3e-14
 Identities = 65/200 (32%), Positives = 96/200 (48%), Gaps = 13/200 (6%)

Query: 2   SDDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS---DTHR 58
           SD    +  AP  +  P   TV      TL+C A G P P I+W + G+ +     D+  
Sbjct: 241 SDPGAENSVAPSFLVGPSPKTVREGDTVTLDCVANGVPKPQIKWLRNGMDLDFNDLDSRF 300

Query: 59  SILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ 118
           SI+  G L    A       D+G Y C A+N+  +  ++ AT+ V     +F   P+   
Sbjct: 301 SIVGTGSLQISSAED----IDSGNYQCRASNTVDSLDAQ-ATVQVQE-PPKFIKAPKDTT 354

Query: 119 SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY 178
           + + D   L+C    G P+P + W KNG   L   +  M LVDG NL I     +DAG +
Sbjct: 355 AHEKDEPELKC-DIWGKPKPVIRWLKNGD--LITPNDYMQLVDGHNLKILGLLNSDAGMF 411

Query: 179 QCIARNAAGTRESAIATLKI 198
           QC+  NAAG+  +A A L++
Sbjct: 412 QCVGTNAAGSVHAA-ARLRV 430



 Score = 83.0 bits (196), Expect = 4e-14
 Identities = 96/398 (24%), Positives = 155/398 (38%), Gaps = 47/398 (11%)

Query: 110 FRLEPESKQSAQGDTVVLEC-----LPPRGSPEPN------VYWK-KNGQTLLFDGDSRM 157
           F LEP+     +G +V+L+C     +   G  + N      + W+  +GQ L+  GD+  
Sbjct: 37  FTLEPQDAVVPEGHSVLLQCAGTASIGRGGKSKSNLPSSVSIRWRGPDGQDLVIVGDTFR 96

Query: 158 HLVDGGNLVIQDARQTDA--GRYQCI-ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQ 214
             +  G+L I    +     G YQC+      G+  S  A + I  +P L     +    
Sbjct: 97  TQLKNGSLYISSVEENRGLTGAYQCLLTAEGVGSILSRPALVAIVRQPDLNQDFLETYLL 156

Query: 215 TGSSVTFQCRVGGDPLPD-----VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGE 269
            G +  F+C +G     +     V W +      +   R+ VL +G+L +D V  +D G 
Sbjct: 157 PGQTAYFRCMLGEANWQEGVKHSVQWLKDDLPLPLDKLRMVVLPNGALEIDEVGPSDRGS 216

Query: 270 YSCEAEN-SVGAVSASGYLTVYDP----------PSINLSPNSVNVESGNVARFTCTATG 318
           Y C   + S   +S+   L +  P          PS  + P+   V  G+     C A G
Sbjct: 217 YQCNVTSGSSSRLSSKTNLNIKKPSDPGAENSVAPSFLVGPSPKTVREGDTVTLDCVANG 276

Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD--GVTVLTINDTDKNDSRNTIVCSAVN 376
            P+P + W        +  GM  D     + F   G   L I+  +  DS N   C A N
Sbjct: 277 VPKPQIKW--------LRNGMDLDFNDLDSRFSIVGTGSLQISSAEDIDSGN-YQCRASN 327

Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436
              S   +  + V     + PP     P + T   K      C     P+P+I W   G+
Sbjct: 328 TVDSLDAQATVQV-----QEPPKFIKAPKDTTAHEKDEPELKCDIWGKPKPVIRWLKNGD 382

Query: 437 ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
            +  N    + +   L +  L  SD+G + CV ++  G
Sbjct: 383 LITPNDYMQLVDGHNLKILGLLNSDAGMFQCVGTNAAG 420



 Score = 74.9 bits (176), Expect = 1e-11
 Identities = 82/323 (25%), Positives = 134/323 (41%), Gaps = 43/323 (13%)

Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
           LP  P   +   V    VTLSW +  +  +  ++ Y V          NN+ R  +    
Sbjct: 610 LPSQPRDLVAQIVKSRFVTLSWVEPLQ-NAGDVVYYTVYY------KMNNSEREQK---- 658

Query: 563 IARRVHQTHYV-VKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVS 621
           +  + H    V ++SL+PG TY F V    + G SG S     V+   + N      G  
Sbjct: 659 MVTKSHDDQQVNIQSLLPGRTYQFRVEANTNFG-SGASSAPLEVSTQPEVNI----AGPP 713

Query: 622 NSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMK 681
            + E       +  V+  E T  + + +K               +Y+   D+    Y   
Sbjct: 714 RNFEGYARSHKEIYVKWEEPTVTNGEILKYR-------------VYYSENDSGADLYHDS 760

Query: 682 TILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMF 741
           T L +       +T LR +T Y   ++PF +   G  S     +T    P  PP N+ + 
Sbjct: 761 TALEA------VLTELRPHTDYVISVVPFNRNGMGDSSAEIRVKTFSSTPSEPPNNVTLE 814

Query: 742 ILNTTTVHLKWSPPELQLQNGIITGYNV-VVNWLDVPANKSMVAINTTVHQATSLIMTNL 800
           + +++++ + W PP  + +NG ITGY +    + D P  KS  A N    +     ++NL
Sbjct: 815 VTSSSSITVHWEPPAEEDRNGQITGYKIRYRKFKDAPQVKSTPA-NIRYFE-----LSNL 868

Query: 801 TSGVSYSVQIAAETIIGLGPFSQ 823
                Y V+IAA T+ G GPF++
Sbjct: 869 DRNAEYQVKIAAMTVNGSGPFTE 891



 Score = 55.2 bits (127), Expect = 1e-05
 Identities = 51/191 (26%), Positives = 83/191 (43%), Gaps = 17/191 (8%)

Query: 694  ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPP--INIEMFILNTTTVHLK 751
            I  LR  T+YEF +     + E   S S +  T  +VP  PP  + + +  +N  TV ++
Sbjct: 1069 INDLRPNTQYEFAVKVVKGRRESSWSMSVLNSTYQNVPVTPPREVTVRLDEMNPPTVIVQ 1128

Query: 752  WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811
            W PP+  L  G ITGYN+     D        ++     + T L++ NL    +Y  ++ 
Sbjct: 1129 WIPPKHTL--GQITGYNIYYT-TDTTKRDRDWSVEAFAGEETMLMLPNLKPYTTYYFKVQ 1185

Query: 812  AETIIGL--GPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETWFYFLIGAIV 869
            A T  G    PFS  V +   S +V +          E   +A     E   Y +I A  
Sbjct: 1186 ARTTKGANNAPFSALVSYT-TSAAVTMQ---------EPDTIAKGIDNEKLLYIIIAATA 1235

Query: 870  LFKIIVIAGII 880
            +  ++V+ G++
Sbjct: 1236 VVLLVVLLGVL 1246



 Score = 35.5 bits (78), Expect = 8.9
 Identities = 38/152 (25%), Positives = 60/152 (39%), Gaps = 13/152 (8%)

Query: 677 EYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVP-DGPP 735
           E E K +  S+D     I SL     Y+F +        G  S      T  +V   GPP
Sbjct: 654 EREQKMVTKSHDDQQVNIQSLLPGRTYQFRVEANTNFGSGASSAPLEVSTQPEVNIAGPP 713

Query: 736 INIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSL 795
            N E +  +   +++KW  P   + NG I  Y V  +  D  A+          H +T+L
Sbjct: 714 RNFEGYARSHKEIYVKWEEP--TVTNGEILKYRVYYSENDSGAD--------LYHDSTAL 763

Query: 796 --IMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
             ++T L     Y + +      G+G  S ++
Sbjct: 764 EAVLTELRPHTDYVISVVPFNRNGMGDSSAEI 795


>UniRef50_O94898 Cluster: Leucine-rich repeats and
           immunoglobulin-like domains protein 2 precursor; n=10;
           Euteleostomi|Rep: Leucine-rich repeats and
           immunoglobulin-like domains protein 2 precursor - Homo
           sapiens (Human)
          Length = 1065

 Score =  109 bits (261), Expect = 6e-22
 Identities = 70/245 (28%), Positives = 113/245 (46%), Gaps = 17/245 (6%)

Query: 106 LREEFRLEPESKQSAQGDTVVLECLPPRGSPEP-NVYWKKNGQTLLFDGDSR---MHLVD 161
           L+ + R  PE+  + +G  V L C     S  P +  W+K+ + +L+D D+     +   
Sbjct: 496 LKPQIRTHPETIIALRGMNVTLTCTAVSSSDSPMSTVWRKDSE-ILYDVDTENFVRYWQQ 554

Query: 162 GGN-------LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQ 214
            G        L + +   TD G+YQCI  N  G+  S  A L ++  P  +  P D+  +
Sbjct: 555 AGEALEYTSILHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEMPSFLKTPMDLTIR 614

Query: 215 TGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL----DDGSLRLDNVILADEGEY 270
           TG+    +C   G P P + W++  GG + P  R + +    +D    + NV + D G Y
Sbjct: 615 TGAMARLECAAEGHPAPQISWQKD-GGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIY 673

Query: 271 SCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
           SC A+N+ G +SA+  LTV + PS         V  G  A   C A G P P + W+ + 
Sbjct: 674 SCMAQNTAGGLSANASLTVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDD 733

Query: 331 NRTII 335
              ++
Sbjct: 734 GPLLV 738



 Score = 94.7 bits (225), Expect = 1e-17
 Identities = 88/305 (28%), Positives = 127/305 (41%), Gaps = 14/305 (4%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRA-GGSPSP-AIRWYKGG-VLVVSDTHRSIL---PAG- 64
           P I   P  +   R    TL C A   S SP +  W K   +L   DT   +     AG 
Sbjct: 498 PQIRTHPETIIALRGMNVTLTCTAVSSSDSPMSTVWRKDSEILYDVDTENFVRYWQQAGE 557

Query: 65  GLFFLRATH--GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122
            L +    H      +D G Y C  TN +G+  S+ A L V  +   F   P       G
Sbjct: 558 ALEYTSILHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEM-PSFLKTPMDLTIRTG 616

Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQT-LLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQC 180
               LEC    G P P + W+K+G T      + RMH++   ++  I + +  D G Y C
Sbjct: 617 AMARLECAA-EGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSC 675

Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
           +A+N AG   SA A+L +   P  I   ED     G +   QC  GG P P + W +  G
Sbjct: 676 MAQNTAGGL-SANASLTVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDG 734

Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
              +         +  L + +  L D G+Y+C   N++G      YL V   P+ + S +
Sbjct: 735 PLLVTERHFFAAANQLLIIVDAGLEDAGKYTCIMSNTLGTERGHIYLNVISSPNCDSSQS 794

Query: 301 SVNVE 305
           S+  E
Sbjct: 795 SIGHE 799



 Score = 93.5 bits (222), Expect = 3e-17
 Identities = 65/194 (33%), Positives = 93/194 (47%), Gaps = 16/194 (8%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG---VLVVSDTHRSILP 62
           +T  E P  ++ P+D+T+     A L C A G P+P I W K G        +    ++P
Sbjct: 596 LTVNEMPSFLKTPMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMP 655

Query: 63  AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQ 121
              +FF+   + ++  D G+Y C A N+ G   S NA+L   VL     + P E K   +
Sbjct: 656 EDDVFFI--ANVKI-EDMGIYSCMAQNTAG-GLSANASL--TVLETPSFIRPLEDKTVTR 709

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQ 179
           G+T VL+C+   GSP P + W K+   LL    +  H     N  L+I DA   DAG+Y 
Sbjct: 710 GETAVLQCI-AGGSPAPRLNWTKDDGPLLV---TERHFFAAANQLLIIVDAGLEDAGKYT 765

Query: 180 CIARNAAGTRESAI 193
           CI  N  GT    I
Sbjct: 766 CIMSNTLGTERGHI 779



 Score = 88.2 bits (209), Expect = 1e-15
 Identities = 77/289 (26%), Positives = 115/289 (39%), Gaps = 25/289 (8%)

Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRV--GGDPLPDVLWRRSA----GGGNMPLGRV---- 249
           +KP + T PE ++A  G +VT  C      D     +WR+ +            R     
Sbjct: 496 LKPQIRTHPETIIALRGMNVTLTCTAVSSSDSPMSTVWRKDSEILYDVDTENFVRYWQQA 555

Query: 250 -KVLDDGS-LRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSVNVES 306
            + L+  S L L NV   DEG+Y C   N  G+  S    LTV + PS   +P  + + +
Sbjct: 556 GEALEYTSILHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEMPSFLKTPMDLTIRT 615

Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
           G +AR  C A G P P + W  +G     FP     + H     D   +  +    K + 
Sbjct: 616 GAMARLECAAEGHPAPQISWQKDGGTD--FPAARERRMHVMPEDDVFFIANV----KIED 669

Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
                C A N AG       LTV        P+      ++T+     AV  C A  +P 
Sbjct: 670 MGIYSCMAQNTAGGLSANASLTVLETPSFIRPL-----EDKTVTRGETAVLQCIAGGSPA 724

Query: 427 PIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
           P + W  + G  L+         +  L++ D    D+G YTC+ S+  G
Sbjct: 725 PRLNWTKDDGPLLVTERHFFAAANQLLIIVDAGLEDAGKYTCIMSNTLG 773


>UniRef50_Q61YY0 Cluster: Putative uncharacterized protein CBG03355;
           n=1; Caenorhabditis briggsae|Rep: Putative
           uncharacterized protein CBG03355 - Caenorhabditis
           briggsae
          Length = 1055

 Score =  108 bits (260), Expect = 8e-22
 Identities = 102/423 (24%), Positives = 170/423 (40%), Gaps = 40/423 (9%)

Query: 78  SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
           S  G Y C A+N +GTA S    L +  L    + E +  +  +G+++ L C PPRG P 
Sbjct: 73  SHQGYYQCFASNIFGTALSNKMHLRLGSLEHFPKREIQILKIKEGESLTLNCTPPRGIPP 132

Query: 138 PNVYW---KKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGR---YQCIARNAAGTRE 190
           P + W     +  +++    SR   VD  G L       +D      Y+C A +     E
Sbjct: 133 PKIIWLYRSLDDSSVIETIRSRHITVDNNGRLHFSSVELSDGKPTLVYECAATSPILRGE 192

Query: 191 SAIAT-LKIHIKPY---------LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
                 +++ I+P          L   P +V  + G  +  QC  GG PLP + W  S  
Sbjct: 193 YRSGDRVQLDIEPSQDKSYPVKKLSVSPSEVTVRAGGQLKLQCVFGGRPLPTIFW--SKV 250

Query: 241 GGNMPLGRVKVL-----DDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
            G +P  R+K L     D G SL ++NV   D G Y C   + V  V+    + V   P 
Sbjct: 251 DGELPKSRIKDLTTHESDFGRSLIVENVHPDDAGVYECRGRHLVHTVN----VRVMAAPF 306

Query: 295 INLSP-NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
               P   +++   +     C A G+P P + WS+ G        ++ D      + D  
Sbjct: 307 WEFEPPRDISLPEESTGELECLAGGQPTPIITWSMNGK---FLHELAEDSRRV--LLDHG 361

Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413
            +L +   + +       C+A N  G  F    + V +     P        +  + + S
Sbjct: 362 RILRVRSLNHDLDTGVYQCNASNPLGYVFANAFVHVRA---HAPFFRMPAARHWKVVLHS 418

Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQ--NHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
             +  C     PE I+ W    +  +Q    +  +  + T ++ D++ +D G Y C  S+
Sbjct: 419 TVILDCDVDAAPEAIVRWVDADDRPLQVVEGKNKLFPNHTFMIYDVNSADEGLYYCNVSN 478

Query: 472 RHG 474
           ++G
Sbjct: 479 KYG 481



 Score = 70.1 bits (164), Expect = 3e-10
 Identities = 81/281 (28%), Positives = 107/281 (38%), Gaps = 22/281 (7%)

Query: 18  PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
           P +VTV       L C  GG P P I W K    +     + +      F        VH
Sbjct: 220 PSEVTVRAGGQLKLQCVFGGRPLPTIFWSKVDGELPKSRIKDLTTHESDFGRSLIVENVH 279

Query: 78  -SDAGVYWCEATNSYGTARSRNATLHVAVLREEF-RLEPESKQS-AQGDTVVLECLPPRG 134
             DAGVY C         R    T++V V+   F   EP    S  +  T  LECL   G
Sbjct: 280 PDDAGVYECR-------GRHLVHTVNVRVMAAPFWEFEPPRDISLPEESTGELECL-AGG 331

Query: 135 SPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNL--VIQDARQTDAGRYQCIARNAAG-TRE 190
            P P + W  NG+ L     DSR  L+D G +  V       D G YQC A N  G    
Sbjct: 332 QPTPIITWSMNGKFLHELAEDSRRVLLDHGRILRVRSLNHDLDTGVYQCNASNPLGYVFA 391

Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL---- 246
           +A   ++ H   + +           S+V   C V   P   V W       + PL    
Sbjct: 392 NAFVHVRAHAPFFRMPAARHWKVVLHSTVILDCDVDAAPEAIVRW---VDADDRPLQVVE 448

Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYL 287
           G+ K+  + +  + +V  ADEG Y C   N  G   A+  L
Sbjct: 449 GKNKLFPNHTFMIYDVNSADEGLYYCNVSNKYGINRATNRL 489



 Score = 68.1 bits (159), Expect = 1e-09
 Identities = 94/371 (25%), Positives = 156/371 (42%), Gaps = 44/371 (11%)

Query: 142 WKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
           W K+G+    + D  +   +   G++V      +  G YQC A N  GT  S    L++ 
Sbjct: 40  WLKDGEPFEINSDDVVWQKESQSGSIVFMKPHISHQGYYQCFASNIFGTALSNKMHLRLG 99

Query: 200 IKPYLITGPEDVVA-QTGSSVTFQCRVG-GDPLPDVLWR-RSAGGGNM----PLGRVKVL 252
              +       ++  + G S+T  C    G P P ++W  RS    ++        + V 
Sbjct: 100 SLEHFPKREIQILKIKEGESLTLNCTPPRGIPPPKIIWLYRSLDDSSVIETIRSRHITVD 159

Query: 253 DDGSLRLDNVILADEGE---YSCEAENSV--GAVSASGYLTVYDPPS---------INLS 298
           ++G L   +V L+D      Y C A + +  G   +   + +   PS         +++S
Sbjct: 160 NNGRLHFSSVELSDGKPTLVYECAATSPILRGEYRSGDRVQLDIEPSQDKSYPVKKLSVS 219

Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWS-VEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
           P+ V V +G   +  C   GRP PT+FWS V+G      P  SR K   T   D    L 
Sbjct: 220 PSEVTVRAGGQLKLQCVFGGRPLPTIFWSKVDGE----LP-KSRIKDLTTHESDFGRSLI 274

Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
           + +   +D+     C   +   +  VR  +     +  PP  I       +LP +S    
Sbjct: 275 VENVHPDDA-GVYECRGRHLVHTVNVR-VMAAPFWEFEPPRDI-------SLPEESTGEL 325

Query: 418 PCTAICTPEPIIAWYFEGE---ALIQNHRRNVTNDGTLV-LKDLDKS-DSGTYTCVASSR 472
            C A   P PII W   G+    L ++ RR + + G ++ ++ L+   D+G Y C AS+ 
Sbjct: 326 ECLAGGQPTPIITWSMNGKFLHELAEDSRRVLLDHGRILRVRSLNHDLDTGVYQCNASNP 385

Query: 473 HGKYVWSGALL 483
            G YV++ A +
Sbjct: 386 LG-YVFANAFV 395



 Score = 68.1 bits (159), Expect = 1e-09
 Identities = 51/177 (28%), Positives = 76/177 (42%), Gaps = 10/177 (5%)

Query: 16  EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL---VVSDTHRSILPAGGLFFLRAT 72
           E P D+++       L C AGG P+P I W   G     +  D+ R +L  G +  +R+ 
Sbjct: 310 EPPRDISLPEESTGELECLAGGQPTPIITWSMNGKFLHELAEDSRRVLLDHGRILRVRSL 369

Query: 73  HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTVVLECL 130
           +  +  D GVY C A+N  G   + NA +HV      FR+ P ++  +     TV+L+C 
Sbjct: 370 NHDL--DTGVYQCNASNPLGYVFA-NAFVHVRAHAPFFRM-PAARHWKVVLHSTVILDC- 424

Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
               +PE  V W       L   + +  L      +I D    D G Y C   N  G
Sbjct: 425 DVDAAPEAIVRWVDADDRPLQVVEGKNKLFPNHTFMIYDVNSADEGLYYCNVSNKYG 481


>UniRef50_UPI0000D55E60 Cluster: PREDICTED: similar to CG32796-PB,
           isoform B; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG32796-PB, isoform B - Tribolium castaneum
          Length = 827

 Score =  108 bits (259), Expect = 1e-21
 Identities = 80/258 (31%), Positives = 115/258 (44%), Gaps = 15/258 (5%)

Query: 80  AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
           AG Y C A        S    L +A + E    E        G+TV   C PP  +PEP 
Sbjct: 110 AGDYQCLAYYGASVVASIPWRLTIANISEFPPQEKIDVTVIPGNTVNWRCEPPEANPEPY 169

Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA-TLKI 198
           + + KNG  +          V   +L+I +    ++G Y C A N    + S +   LK+
Sbjct: 170 IDYHKNGVYV-----PPFVQVVTKSLIIPNVTSGNSGSYTCKAGNVCTEKFSPVLFNLKV 224

Query: 199 HIK-----PYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL 252
             +     P  I  P  V   T G  V  +C   G+PLP V+WR+  G   +P GR + L
Sbjct: 225 DKRAPREPPKFIVRPRSVYNVTKGDKVLLECSAVGNPLPKVVWRKITG--IIPEGRSE-L 281

Query: 253 DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARF 312
             G L + N+  +D G Y C  +NS+G V  S  L   + P+IN   +S++V  G     
Sbjct: 282 TPGGLIIKNISASDNGIYECTHDNSLGKVVHSITLNYNEAPTINCPQDSIDVNQGEDLEL 341

Query: 313 TCTATGRPEPTMFWSVEG 330
            CT TG P+P + W + G
Sbjct: 342 ECTVTGNPDPEITWFLNG 359



 Score = 64.5 bits (150), Expect = 2e-08
 Identities = 55/186 (29%), Positives = 81/186 (43%), Gaps = 14/186 (7%)

Query: 10  EAPYIIEQPLDV-TVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
           E P  I +P  V  V +     L C A G+P P + W K  +  +    RS L  GGL  
Sbjct: 231 EPPKFIVRPRSVYNVTKGDKVLLECSAVGNPLPKVVWRK--ITGIIPEGRSELTPGGLII 288

Query: 69  LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
              +     SD G+Y C   NS G     + TL+            +S    QG+ + LE
Sbjct: 289 KNISA----SDNGIYECTHDNSLGKV-VHSITLNYNEA-PTINCPQDSIDVNQGEDLELE 342

Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
           C    G+P+P + W  NG       D+++ + +G  +  +   +  AG  Q  ARN AGT
Sbjct: 343 CTVT-GNPDPEITWFLNG---FVTKDNKI-ITEGNKIFFKPTEKRHAGNLQVFARNIAGT 397

Query: 189 RESAIA 194
             S+I+
Sbjct: 398 VYSSIS 403



 Score = 40.3 bits (90), Expect = 0.31
 Identities = 36/124 (29%), Positives = 50/124 (40%), Gaps = 7/124 (5%)

Query: 359 NDTDKNDSRNTIVCSAVNYAGSSF--VRGKLTVTSDDDRPPP-IITNGPSNQTLPIKSMA 415
           N T  N    T  C A N     F  V   L V     R PP  I    S   +      
Sbjct: 194 NVTSGNSGSYT--CKAGNVCTEKFSPVLFNLKVDKRAPREPPKFIVRPRSVYNVTKGDKV 251

Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
           +  C+A+  P P + W  +   +I   R  +T  G L++K++  SD+G Y C   +  GK
Sbjct: 252 LLECSAVGNPLPKVVWR-KITGIIPEGRSELTPGG-LIIKNISASDNGIYECTHDNSLGK 309

Query: 476 YVWS 479
            V S
Sbjct: 310 VVHS 313


>UniRef50_Q17AC3 Cluster: Leucine-rich transmembrane protein; n=2;
           Culicidae|Rep: Leucine-rich transmembrane protein -
           Aedes aegypti (Yellowfever mosquito)
          Length = 743

 Score =  108 bits (259), Expect = 1e-21
 Identities = 82/289 (28%), Positives = 127/289 (43%), Gaps = 23/289 (7%)

Query: 113 EPESKQSAQGDTVVLECLPPRGSPEPNVY-WKKNGQTLLFDGDSRMHLV-DGGN-----L 165
           EP+++   +G  V L C     +P+   + WK +   L   G     L  D G      L
Sbjct: 415 EPKTQFGIRGTNVTLVCTATSTAPDVMTFKWKHDNLELPDSGSIVTQLNNDNGTVGTTQL 474

Query: 166 VIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV 225
            I + +   AG+YQCI  NA G   S    + +   P+    P D+  Q G      C  
Sbjct: 475 TIPNIQNGAAGKYQCIITNAYGVVYSQKVKVTVGTFPFFKKTPSDISVQAGKMARLDCAA 534

Query: 226 GGDPLPDVLWRRSAGGGNMPLGRVKVL----DDGSLRLDNVILADEGEYSCEAENSVGAV 281
            GDP P + W +  GG + P  + + +    DDG+  + N  + D G Y+C AEN+ G +
Sbjct: 535 AGDPKPQISWEKD-GGNDFPAAKDRRMHISADDGAFFIMNAQIVDMGVYTCSAENAAGVI 593

Query: 282 SASGYLTVYDPPSINLSPNSVNV-ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340
            AS  + V + P + L P    V E G      C+A+G P+P + W  +G      P + 
Sbjct: 594 KASASVLVLESPML-LKPLETKVAELGTSIVLDCSASGYPKPVILWFKDGE-----PLLV 647

Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389
            +++   A  DG  ++ +  TD +D+     C   N  GS     KL+V
Sbjct: 648 TERHFIIA--DGQLMIIVK-TDFDDA-GDYECQVENEFGSQRGLMKLSV 692



 Score =  100 bits (240), Expect = 2e-19
 Identities = 67/219 (30%), Positives = 100/219 (45%), Gaps = 7/219 (3%)

Query: 80  AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
           AG Y C  TN+YG   S+   + V      F+  P       G    L+C    G P+P 
Sbjct: 484 AGKYQCIITNAYGVVYSQKVKVTVGTF-PFFKKTPSDISVQAGKMARLDCAAA-GDPKPQ 541

Query: 140 VYWKKNG-QTLLFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
           + W+K+G        D RMH+  D G   I +A+  D G Y C A NAAG  +++ + L 
Sbjct: 542 ISWEKDGGNDFPAAKDRRMHISADDGAFFIMNAQIVDMGVYTCSAENAAGVIKASASVLV 601

Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257
           +   P L+   E  VA+ G+S+   C   G P P +LW +  G   +   R  ++ DG L
Sbjct: 602 LE-SPMLLKPLETKVAELGTSIVLDCSASGYPKPVILWFKD-GEPLLVTERHFIIADGQL 659

Query: 258 RLD-NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295
            +       D G+Y C+ EN  G+      L+V + P +
Sbjct: 660 MIIVKTDFDDAGDYECQVENEFGSQRGLMKLSVIEGPEL 698



 Score = 90.2 bits (214), Expect = 3e-16
 Identities = 61/188 (32%), Positives = 91/188 (48%), Gaps = 12/188 (6%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG---VLVVSDTHRSILP 62
           VT G  P+  + P D++V   + A L+C A G P P I W K G        D    I  
Sbjct: 505 VTVGTFPFFKKTPSDISVQAGKMARLDCAAAGDPKPQISWEKDGGNDFPAAKDRRMHISA 564

Query: 63  AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQ 121
             G FF+   + ++  D GVY C A N+ G  +   A+  V VL     L+P E+K +  
Sbjct: 565 DDGAFFI--MNAQI-VDMGVYTCSAENAAGVIK---ASASVLVLESPMLLKPLETKVAEL 618

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
           G ++VL+C    G P+P + W K+G+ LL   +    + DG  ++I      DAG Y+C 
Sbjct: 619 GTSIVLDC-SASGYPKPVILWFKDGEPLLVT-ERHFIIADGQLMIIVKTDFDDAGDYECQ 676

Query: 182 ARNAAGTR 189
             N  G++
Sbjct: 677 VENEFGSQ 684



 Score = 89.4 bits (212), Expect = 5e-16
 Identities = 72/286 (25%), Positives = 116/286 (40%), Gaps = 24/286 (8%)

Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL---WRRS------AGGGNMPLGRVK- 250
           KP+LI  P+      G++VT  C       PDV+   W+        +G     L     
Sbjct: 409 KPHLIDEPKTQFGIRGTNVTLVC-TATSTAPDVMTFKWKHDNLELPDSGSIVTQLNNDNG 467

Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAV-SASGYLTVYDPPSINLSPNSVNVESGNV 309
            +    L + N+     G+Y C   N+ G V S    +TV   P    +P+ ++V++G +
Sbjct: 468 TVGTTQLTIPNIQNGAAGKYQCIITNAYGVVYSQKVKVTVGTFPFFKKTPSDISVQAGKM 527

Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
           AR  C A G P+P + W  +G     FP     + H +A      ++     D       
Sbjct: 528 ARLDCAAAGDPKPQISWEKDGGND--FPAAKDRRMHISADDGAFFIMNAQIVDMG----V 581

Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
             CSA N AG       + V        P++      +   + +  V  C+A   P+P+I
Sbjct: 582 YTCSAENAAGVIKASASVLVLES-----PMLLKPLETKVAELGTSIVLDCSASGYPKPVI 636

Query: 430 AWYFEGEALIQNHRRNVTNDGTL-VLKDLDKSDSGTYTCVASSRHG 474
            W+ +GE L+   R  +  DG L ++   D  D+G Y C   +  G
Sbjct: 637 LWFKDGEPLLVTERHFIIADGQLMIIVKTDFDDAGDYECQVENEFG 682



 Score = 47.6 bits (108), Expect = 0.002
 Identities = 31/88 (35%), Positives = 47/88 (53%), Gaps = 7/88 (7%)

Query: 10  EAPYIIEQPLDVTVARHQPA-TLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLF 67
           E+P +++ PL+  VA    +  L+C A G P P I W+K G  L+V++ H  I+  G L 
Sbjct: 603 ESPMLLK-PLETKVAELGTSIVLDCSASGYPKPVILWFKDGEPLLVTERH-FIIADGQLM 660

Query: 68  FLRATHGRVHSDAGVYWCEATNSYGTAR 95
            +  T      DAG Y C+  N +G+ R
Sbjct: 661 IIVKTD---FDDAGDYECQVENEFGSQR 685



 Score = 45.6 bits (103), Expect = 0.008
 Identities = 56/216 (25%), Positives = 90/216 (41%), Gaps = 14/216 (6%)

Query: 281 VSASGYLTVYDPPSINL--SPNSVNVESGNVARFTCTATGR-PEPTMFWSVEGNRTIIFP 337
           +SAS + + YD P  +L   P +     G      CTAT   P+   F     N  +   
Sbjct: 397 LSASNF-SCYDSPKPHLIDEPKTQFGIRGTNVTLVCTATSTAPDVMTFKWKHDNLELPDS 455

Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397
           G    + +      G T LTI +  +N +     C   N  G  + + K+ VT       
Sbjct: 456 GSIVTQLNNDNGTVGTTQLTIPNI-QNGAAGKYQCIITNAYGVVYSQ-KVKVTVGTF--- 510

Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE---ALIQNHRRNVT-NDGTLV 453
           P     PS+ ++    MA   C A   P+P I+W  +G       ++ R +++ +DG   
Sbjct: 511 PFFKKTPSDISVQAGKMARLDCAAAGDPKPQISWEKDGGNDFPAAKDRRMHISADDGAFF 570

Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLV-DSPI 488
           + +    D G YTC A +  G    S ++LV +SP+
Sbjct: 571 IMNAQIVDMGVYTCSAENAAGVIKASASVLVLESPM 606


>UniRef50_UPI0000DB720E Cluster: PREDICTED: similar to zormin
            CG33484-PA; n=1; Apis mellifera|Rep: PREDICTED: similar
            to zormin CG33484-PA - Apis mellifera
          Length = 3593

 Score =  107 bits (258), Expect = 1e-21
 Identities = 122/506 (24%), Positives = 196/506 (38%), Gaps = 55/506 (10%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
            D TV   +  T  C   G P+P + WYK G+ ++++         G+  L         D
Sbjct: 1742 DATVQEGEKFTFQCNLIGQPTPEVIWYKDGISILNNPDYLTTYIHGICTL-TIEETFAED 1800

Query: 80   AGVYWCEATNSYGTARSRNATLHVAVLREE-------FRLEPESKQSAQGDTVVLECLPP 132
            +  Y C+A N  G+A + +ATL V     E       F  E  +  + +  +  L C   
Sbjct: 1801 SAKYTCKAFNIAGSAET-SATLTVKETAPEEQPSSPVFVKELMASVALENSSHQLNC-TV 1858

Query: 133  RGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRES 191
            +G+P P V W KN   +    D  +   +G   L  ++    D   Y C A N  G + S
Sbjct: 1859 KGNPLPTVQWFKNDVNIDNSPDYVITYNNGEAVLKFEEVFLEDKATYTCKATNKLG-QAS 1917

Query: 192  AIATLKIH------IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
              A L +        KPY +T   + + + G  V  +C   G+P+P + W          
Sbjct: 1918 TSAFLDVEPAEFTSEKPYFVTPLSNAMGRAGQRVKLECEAKGNPMPALTWYHDGRPVEES 1977

Query: 246  LGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGA------VSASGYL---------- 287
            +     +D G  SL +      D G Y+  A+N  G       VS  G L          
Sbjct: 1978 MNLKIQMDGGRTSLVISEAFAKDAGCYTVVAKNEAGEATVTCNVSVKGRLPHETSDSEFA 2037

Query: 288  -TVYDP--PSINLSPNSVNVESGNVARFTCTATGRPEPTMFW-------SVEGNRTIIFP 337
             +  +P  P I +    + V+ G   R  C   G+PEP + W           +  ++F 
Sbjct: 2038 CSDMEPVVPKIQMPLKDLKVQEGLSVRLDCVIVGQPEPEVIWYHDDQPVKESADFQLLFQ 2097

Query: 338  GMSRDKYHATAVFD--GV-TVLTINDTDKNDSRNTIVCSAVNYAGS-SFVRGKLTVTSDD 393
            G         A  D  GV  V+ IN   +  S+ T+  + V  +      R ++  T   
Sbjct: 2098 GDKCSLVIHEAFLDDAGVYKVVAINSGGEASSQCTLTVTPVTVSEKLDRARTEIEETFVA 2157

Query: 394  DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNV--TNDGT 451
              PP  +   P++  +     A+F C  +  P+P + W+ +   + +N R  +    DGT
Sbjct: 2158 GSPPRFV-KLPTDSLVAEGETAIFECAVVGEPKPELKWFSDSGEVTENERILIQRKEDGT 2216

Query: 452  LVLK--DLDKSDSGTYTCVASSRHGK 475
             +LK       D G Y   A + HG+
Sbjct: 2217 SILKISSAIPEDKGNYVVKAFNEHGE 2242



 Score = 95.9 bits (228), Expect = 6e-18
 Identities = 135/609 (22%), Positives = 222/609 (36%), Gaps = 74/609 (12%)

Query: 11   APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
            +P  +++ +      +    LNC   G+P P ++W+K  V + +     I    G   L+
Sbjct: 1834 SPVFVKELMASVALENSSHQLNCTVKGNPLPTVQWFKNDVNIDNSPDYVITYNNGEAVLK 1893

Query: 71   ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA----VLREEFRLEPESKQSAQ-GDTV 125
                 +  D   Y C+ATN  G A S +A L V        + + + P S    + G  V
Sbjct: 1894 FEEVFL-EDKATYTCKATNKLGQA-STSAFLDVEPAEFTSEKPYFVTPLSNAMGRAGQRV 1951

Query: 126  VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIAR 183
             LEC   +G+P P + W  +G+ +    + ++ + DGG  +LVI +A   DAG Y  +A+
Sbjct: 1952 KLEC-EAKGNPMPALTWYHDGRPVEESMNLKIQM-DGGRTSLVISEAFAKDAGCYTVVAK 2009

Query: 184  NAAG-----------------TRESAIATLKIH-IKPYLITGPEDVVAQTGSSVTFQCRV 225
            N AG                 T +S  A   +  + P +    +D+  Q G SV   C +
Sbjct: 2010 NEAGEATVTCNVSVKGRLPHETSDSEFACSDMEPVVPKIQMPLKDLKVQEGLSVRLDCVI 2069

Query: 226  GGDPLPDVLWRRSAGGGNMPLGRVKVL--DDGSLRLDNVILADEGEYSCEAENSVGAVSA 283
             G P P+V+W               +   D  SL +    L D G Y   A NS G  S+
Sbjct: 2070 VGQPEPEVIWYHDDQPVKESADFQLLFQGDKCSLVIHEAFLDDAGVYKVVAINSGGEASS 2129

Query: 284  SGYLTVY----------------------DPPSINLSPNSVNVESGNVARFTCTATGRPE 321
               LTV                        PP     P    V  G  A F C   G P+
Sbjct: 2130 QCTLTVTPVTVSEKLDRARTEIEETFVAGSPPRFVKLPTDSLVAEGETAIFECAVVGEPK 2189

Query: 322  PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381
            P + W  +            ++       DG ++L I+     D  N +V  A N  G +
Sbjct: 2190 PELKWFSDSGEV-----TENERILIQRKEDGTSILKISSAIPEDKGNYVV-KAFNEHGEA 2243

Query: 382  FVRGKLTVTS-------------DDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428
                +L + S             ++    P       ++ +       F C  +  P P 
Sbjct: 2244 KAFARLVIRSLGDFRRKEEFVKMEEKLIAPTFKERFEDRRVMEGVSTKFECIVVGKPSPK 2303

Query: 429  IAWYFEGEALI-QNHRRNVTND-GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
            I W F    +  ++   +V+ D   L + +   + +GT +CVA +  GK + S  L +  
Sbjct: 2304 IQWLFNDRPVHGKDFLVSVSGDRQVLTIPETGSTHAGTISCVAENAAGKAICSARLEIGG 2363

Query: 487  PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRE 546
                 +       V  L         H  + +    S  ++   G S +L    +  +  
Sbjct: 2364 RSVEEVRKVGEKRVVDLVERSPADEMHAASSSEKHFSSEKSEGEGESQVLTKMSQTITES 2423

Query: 547  TLSGNNTPR 555
            T +   T +
Sbjct: 2424 TTTHKTTKK 2432



 Score = 79.8 bits (188), Expect = 4e-13
 Identities = 76/306 (24%), Positives = 115/306 (37%), Gaps = 25/306 (8%)

Query: 188  TRESAIATLKIHIKPYL---ITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-- 241
            TRE ++  +     P L    T P  D   Q G   TFQC + G P P+V+W +      
Sbjct: 1716 TREKSVERMHKESVPPLAPEFTIPLHDATVQEGEKFTFQCNLIGQPTPEVIWYKDGISIL 1775

Query: 242  GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PPSINLSP 299
             N       +    +L ++     D  +Y+C+A N  G+   S  LTV +  P     SP
Sbjct: 1776 NNPDYLTTYIHGICTLTIEETFAEDSAKYTCKAFNIAGSAETSATLTVKETAPEEQPSSP 1835

Query: 300  NSVNVESGNVA------RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
              V     +VA      +  CT  G P PT+ W            +     +     +G 
Sbjct: 1836 VFVKELMASVALENSSHQLNCTVKGNPLPTVQWFKND------VNIDNSPDYVITYNNGE 1889

Query: 354  TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT-SDDDRPPPIITNGPSNQTLPIK 412
             VL   +    D + T  C A N  G +     L V  ++     P      SN      
Sbjct: 1890 AVLKFEEVFLED-KATYTCKATNKLGQASTSAFLDVEPAEFTSEKPYFVTPLSNAMGRAG 1948

Query: 413  SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVA 469
                  C A   P P + WY +G  + ++    +  DG   +LV+ +    D+G YT VA
Sbjct: 1949 QRVKLECEAKGNPMPALTWYHDGRPVEESMNLKIQMDGGRTSLVISEAFAKDAGCYTVVA 2008

Query: 470  SSRHGK 475
             +  G+
Sbjct: 2009 KNEAGE 2014



 Score = 78.2 bits (184), Expect = 1e-12
 Identities = 111/443 (25%), Positives = 173/443 (39%), Gaps = 72/443 (16%)

Query: 8    SGEAPYIIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66
            + E PY +  PL   + R  Q   L C A G+P PA+ WY  G  V    +  I   GG 
Sbjct: 1930 TSEKPYFVT-PLSNAMGRAGQRVKLECEAKGNPMPALTWYHDGRPVEESMNLKIQMDGGR 1988

Query: 67   FFLRATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLRE----EFR---LEP---- 114
              L  +      DAG Y   A N  G A  + N ++   +  E    EF    +EP    
Sbjct: 1989 TSLVISEA-FAKDAGCYTVVAKNEAGEATVTCNVSVKGRLPHETSDSEFACSDMEPVVPK 2047

Query: 115  -----ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQ 168
                 +  +  +G +V L+C+   G PEP V W  + Q +    D ++    D  +LVI 
Sbjct: 2048 IQMPLKDLKVQEGLSVRLDCVIV-GQPEPEVIWYHDDQPVKESADFQLLFQGDKCSLVIH 2106

Query: 169  DARQTDAGRYQCIARNAAGTRES----AIATLKIHIK-----------------PYLITG 207
            +A   DAG Y+ +A N+ G   S     +  + +  K                 P  +  
Sbjct: 2107 EAFLDDAGVYKVVAINSGGEASSQCTLTVTPVTVSEKLDRARTEIEETFVAGSPPRFVKL 2166

Query: 208  PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDGS--LRLDNVIL 264
            P D +   G +  F+C V G+P P++ W   +G         ++  +DG+  L++ + I 
Sbjct: 2167 PTDSLVAEGETAIFECAVVGEPKPELKWFSDSGEVTENERILIQRKEDGTSILKISSAIP 2226

Query: 265  ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA-------------- 310
             D+G Y  +A N  G   A   L +            V +E   +A              
Sbjct: 2227 EDKGNYVVKAFNEHGEAKAFARLVIRSLGDFRRKEEFVKMEEKLIAPTFKERFEDRRVME 2286

Query: 311  ----RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
                +F C   G+P P + W +  +R +        K    +V     VLTI +T    +
Sbjct: 2287 GVSTKFECIVVGKPSPKIQW-LFNDRPV------HGKDFLVSVSGDRQVLTIPETGSTHA 2339

Query: 367  RNTIVCSAVNYAGSSFVRGKLTV 389
              TI C A N AG +    +L +
Sbjct: 2340 -GTISCVAENAAGKAICSARLEI 2361



 Score = 67.3 bits (157), Expect = 2e-09
 Identities = 56/200 (28%), Positives = 83/200 (41%), Gaps = 15/200 (7%)

Query: 293  PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
            P   +  +   V+ G    F C   G+P P + W  +G   +  P       + T    G
Sbjct: 1734 PEFTIPLHDATVQEGEKFTFQCNLIGQPTPEVIWYKDGISILNNPD------YLTTYIHG 1787

Query: 353  VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV--TSDDDRP-PPIITNGPSNQTL 409
            +  LTI +T   DS     C A N AGS+     LTV  T+ +++P  P+          
Sbjct: 1788 ICTLTIEETFAEDSAK-YTCKAFNIAGSAETSATLTVKETAPEEQPSSPVFVKELMASVA 1846

Query: 410  PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT--NDGTLVLK--DLDKSDSGTY 465
               S     CT    P P + W F+ +  I N    V   N+G  VLK  ++   D  TY
Sbjct: 1847 LENSSHQLNCTVKGNPLPTVQW-FKNDVNIDNSPDYVITYNNGEAVLKFEEVFLEDKATY 1905

Query: 466  TCVASSRHGKYVWSGALLVD 485
            TC A+++ G+   S  L V+
Sbjct: 1906 TCKATNKLGQASTSAFLDVE 1925



 Score = 63.3 bits (147), Expect = 4e-08
 Identities = 47/178 (26%), Positives = 75/178 (42%), Gaps = 7/178 (3%)

Query: 121  QGDTVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179
            QG  ++LE +   G P+P++ W KNGQ L   DG +  +  +   L ++     DAGRY 
Sbjct: 2542 QGTDIILEGIID-GFPQPSISWSKNGQELKTKDGITITYAHNHVRLELKKVNVKDAGRYT 2600

Query: 180  CIARNAAGTRESA--IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
            C A N  G+  S   +   K    P      +  V + G  V  +  + G P P V W +
Sbjct: 2601 CTASNEVGSASSTADLVVKKTIFPPVFGRRLQAQVVKRGERVNMEVEITGTPEPTVTWFK 2660

Query: 238  SAGGGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
                       +++   G+   L +D    A  G+Y   A N+ G   +     V++P
Sbjct: 2661 DDVPIKERPPELRIKQQGNCYMLIIDKAEKAHAGKYMVRATNAGGEAQSIADFAVFEP 2718



 Score = 55.6 bits (128), Expect = 8e-06
 Identities = 56/219 (25%), Positives = 94/219 (42%), Gaps = 30/219 (13%)

Query: 3    DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL- 61
            ++   +G  P  ++ P D  VA  + A   C   G P P ++W+      V++  R ++ 
Sbjct: 2152 EETFVAGSPPRFVKLPTDSLVAEGETAIFECAVVGEPKPELKWFSDSG-EVTENERILIQ 2210

Query: 62   -PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVL-----REEF-RLEP 114
                G   L+ +   +  D G Y  +A N +G A++  A L +  L     +EEF ++E 
Sbjct: 2211 RKEDGTSILKIS-SAIPEDKGNYVVKAFNEHGEAKA-FARLVIRSLGDFRRKEEFVKMEE 2268

Query: 115  -----------ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG 163
                       E ++  +G +   EC+   G P P + W  N + +   G   +  V G 
Sbjct: 2269 KLIAPTFKERFEDRRVMEGVSTKFECIVV-GKPSPKIQWLFNDRPV--HGKDFLVSVSGD 2325

Query: 164  N--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
               L I +   T AG   C+A NAAG    AI + ++ I
Sbjct: 2326 RQVLTIPETGSTHAGTISCVAENAAG---KAICSARLEI 2361



 Score = 54.0 bits (124), Expect = 2e-05
 Identities = 45/159 (28%), Positives = 71/159 (44%), Gaps = 7/159 (4%)

Query: 37   GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
            G P P+I W K G  + +    +I  A     L      V  DAG Y C A+N  G+A S
Sbjct: 2554 GFPQPSISWSKNGQELKTKDGITITYAHNHVRLELKKVNV-KDAGRYTCTASNEVGSASS 2612

Query: 97   -RNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155
              +  +   +    F    +++   +G+ V +E +   G+PEP V W K+    + +   
Sbjct: 2613 TADLVVKKTIFPPVFGRRLQAQVVKRGERVNME-VEITGTPEPTVTWFKD-DVPIKERPP 2670

Query: 156  RMHLVDGGN---LVIQDARQTDAGRYQCIARNAAGTRES 191
             + +   GN   L+I  A +  AG+Y   A NA G  +S
Sbjct: 2671 ELRIKQQGNCYMLIIDKAEKAHAGKYMVRATNAGGEAQS 2709



 Score = 49.2 bits (112), Expect = 7e-04
 Identities = 32/130 (24%), Positives = 53/130 (40%), Gaps = 5/130 (3%)

Query: 202  PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLD- 260
            P  ++    ++   G+ +  +  + G P P + W ++        G         +RL+ 
Sbjct: 2529 PRFVSPLTGMIVDQGTDIILEGIIDGFPQPSISWSKNGQELKTKDGITITYAHNHVRLEL 2588

Query: 261  -NVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLSPNSVNVESGNVARFTCTA 316
              V + D G Y+C A N VG+ S++  L V     PP       +  V+ G         
Sbjct: 2589 KKVNVKDAGRYTCTASNEVGSASSTADLVVKKTIFPPVFGRRLQAQVVKRGERVNMEVEI 2648

Query: 317  TGRPEPTMFW 326
            TG PEPT+ W
Sbjct: 2649 TGTPEPTVTW 2658



 Score = 37.5 bits (83), Expect = 2.2
 Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 3/71 (4%)

Query: 425  PEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
            P+P I+W   G+ L       +T   N   L LK ++  D+G YTC AS+  G    +  
Sbjct: 2556 PQPSISWSKNGQELKTKDGITITYAHNHVRLELKKVNVKDAGRYTCTASNEVGSASSTAD 2615

Query: 482  LLVDSPINPNI 492
            L+V   I P +
Sbjct: 2616 LVVKKTIFPPV 2626


>UniRef50_Q4S1C0 Cluster: Chromosome 13 SCAF14769, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 13 SCAF14769, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 620

 Score =  107 bits (258), Expect = 1e-21
 Identities = 62/184 (33%), Positives = 88/184 (47%), Gaps = 3/184 (1%)

Query: 15  IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74
           I +P D+TV    PA L+C+A G P   +RW K GV +        LP G L+  +  H 
Sbjct: 27  ITEPSDLTVLPKDPAVLDCQAHGQPPVTVRWLKNGVRLAESERVHFLPNGSLYIPKIKHT 86

Query: 75  RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRG 134
              SD G Y C + N YG   S+ + L +A +  EF L P      +G      C+    
Sbjct: 87  EEESDEGFYQCLSQNKYGAILSQRSHLTIARI-SEFVLHPVPAVVTEGSVARFSCV-VTS 144

Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194
           SP   + W+ N Q  L     R+ ++  G L I + R  DAG+Y+C+A NAA   +S  A
Sbjct: 145 SPPATITWEFN-QNALAVHTERITVLPNGVLQIHNVRPEDAGQYRCVAANAASRLKSKEA 203

Query: 195 TLKI 198
            L +
Sbjct: 204 ALTV 207



 Score = 84.2 bits (199), Expect = 2e-14
 Identities = 79/293 (26%), Positives = 113/293 (38%), Gaps = 27/293 (9%)

Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
           IT P D+           C+  G P   V W ++ G       RV  L +GSL +  +  
Sbjct: 27  ITEPSDLTVLPKDPAVLDCQAHGQPPVTVRWLKN-GVRLAESERVHFLPNGSLYIPKIKH 85

Query: 265 ----ADEGEYSCEAENSVGAV-SASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGR 319
               +DEG Y C ++N  GA+ S   +LT+       L P    V  G+VARF+C  T  
Sbjct: 86  TEEESDEGFYQCLSQNKYGAILSQRSHLTIARISEFVLHPVPAVVTEGSVARFSCVVTSS 145

Query: 320 PEPTMFW-------SVEGNRTIIFPGMSRDKYHATAVFDG-VTVLTINDTDKNDSRN-TI 370
           P  T+ W       +V   R  + P      ++      G    +  N   +  S+   +
Sbjct: 146 PPATITWEFNQNALAVHTERITVLPNGVLQIHNVRPEDAGQYRCVAANAASRLKSKEAAL 205

Query: 371 VCSAVNYAGSSFVRGK------LTVTSD------DDRPPPIITNGPSNQTLPIKSMAVFP 418
             +      SSF  GK      L V+          R  P I  GP N T  +    V  
Sbjct: 206 TVTRGTDPDSSFPAGKADSVLLLRVSFSCKGPHYKPRQRPRILAGPQNVTASLHQTVVLE 265

Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
           C A   P PII+W       I  +   V  +G LV+ D+    SG Y C A++
Sbjct: 266 CLATGNPSPIISWSRADSKAIDVYNAKVLGNGNLVIADVSSKHSGVYLCRATT 318



 Score = 77.0 bits (181), Expect = 3e-12
 Identities = 57/185 (30%), Positives = 77/185 (41%), Gaps = 8/185 (4%)

Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
           F  EP        D  VL+C    G P   V W KNG  L      R+H +  G+L I  
Sbjct: 26  FITEPSDLTVLPKDPAVLDC-QAHGQPPVTVRWLKNGVRLA--ESERVHFLPNGSLYIPK 82

Query: 170 ARQT----DAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV 225
            + T    D G YQC+++N  G   S  + L I      +  P   V   GS   F C V
Sbjct: 83  IKHTEEESDEGFYQCLSQNKYGAILSQRSHLTIARISEFVLHPVPAVVTEGSVARFSCVV 142

Query: 226 GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV-SAS 284
              P   + W  +     +   R+ VL +G L++ NV   D G+Y C A N+   + S  
Sbjct: 143 TSSPPATITWEFNQNALAVHTERITVLPNGVLQIHNVRPEDAGQYRCVAANAASRLKSKE 202

Query: 285 GYLTV 289
             LTV
Sbjct: 203 AALTV 207



 Score = 52.8 bits (121), Expect = 5e-05
 Identities = 64/227 (28%), Positives = 95/227 (41%), Gaps = 34/227 (14%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
           + P I+  P +VT + HQ   L C A G+PSP I W +     +   +  +L  G L   
Sbjct: 243 QRPRILAGPQNVTASLHQTVVLECLATGNPSPIISWSRADSKAIDVYNAKVLGNGNLVI- 301

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
            A     HS  GVY C AT    T  +RN T+  A       L  +  ++++  T+VL  
Sbjct: 302 -ADVSSKHS--GVYLCRAT----TPGTRNYTVAAA------NLTVQGTENSREATLVL-F 347

Query: 130 LPPRGSP-----EPNVYWKKNGQTLLFDGDSRM---------HLVD----GGNLVIQDAR 171
           L P   P      P++  +   QT    G +R          H       G  LVI    
Sbjct: 348 LQPTNQPTSVSVPPSIVERPESQTRPRAGTARFMCQAEGVPRHASAGSRMGSKLVITQII 407

Query: 172 QTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSS 218
             D   YQC+A +  G+  S +A L + +     + P ++ A+T SS
Sbjct: 408 PEDDAIYQCLAESEEGSVLS-LARLIVVMSEDRPSAPRNIHAETISS 453



 Score = 49.2 bits (112), Expect = 7e-04
 Identities = 40/181 (22%), Positives = 76/181 (41%), Gaps = 9/181 (4%)

Query: 639 IEATPIDSKTIKLMWE--ILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITS 696
           I A  I S  I L WE  + N   +    I++   + +  E E + ++  ND + + +  
Sbjct: 446 IHAETISSSAILLAWEKPLYNADKVIAYSIHYMKAEGLNNE-EYQVVI-GNDTTSYIVDD 503

Query: 697 LRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPE 756
           L     Y F+++ +      + S+     TL+DVP   P  + +   ++T + + W P  
Sbjct: 504 LESARNYSFYIVAYMPMGASRMSDQVSQHTLEDVPLRTP-ELSLTSHSSTDIQVNWQPLP 562

Query: 757 LQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETII 816
            ++  G ++ Y +        A  S VA       +T  ++  L     Y +++AA T  
Sbjct: 563 AKVSRGRLSAYRLSYR----TAADSTVASVEIPQNSTQYLLEGLQPDTIYLLRMAAATRA 618

Query: 817 G 817
           G
Sbjct: 619 G 619



 Score = 46.0 bits (104), Expect = 0.006
 Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 1/74 (1%)

Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLD 260
           +P ++ GP++V A    +V  +C   G+P P + W R A    + +   KVL +G+L + 
Sbjct: 244 RPRILAGPQNVTASLHQTVVLECLATGNPSPIISWSR-ADSKAIDVYNAKVLGNGNLVIA 302

Query: 261 NVILADEGEYSCEA 274
           +V     G Y C A
Sbjct: 303 DVSSKHSGVYLCRA 316



 Score = 45.2 bits (102), Expect = 0.011
 Identities = 53/218 (24%), Positives = 86/218 (39%), Gaps = 43/218 (19%)

Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT 173
           P++  ++   TVVLECL   G+P P + W +     +   ++++  +  GNLVI D    
Sbjct: 251 PQNVTASLHQTVVLECLAT-GNPSPIISWSRADSKAIDVYNAKV--LGNGNLVIADVSSK 307

Query: 174 DAGRYQCIA-----RN---------AAGTRESAIATL-----------KIHIKPYLITGP 208
            +G Y C A     RN           GT  S  ATL            + + P ++  P
Sbjct: 308 HSGVYLCRATTPGTRNYTVAAANLTVQGTENSREATLVLFLQPTNQPTSVSVPPSIVERP 367

Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268
           E        +  F C+  G P      R ++ G  M            L +  +I  D+ 
Sbjct: 368 ESQTRPRAGTARFMCQAEGVP------RHASAGSRM---------GSKLVITQIIPEDDA 412

Query: 269 EYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
            Y C AE+  G+V +   L V        +P +++ E+
Sbjct: 413 IYQCLAESEEGSVLSLARLIVVMSEDRPSAPRNIHAET 450



 Score = 44.8 bits (101), Expect = 0.015
 Identities = 48/201 (23%), Positives = 79/201 (39%), Gaps = 21/201 (10%)

Query: 277 SVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF 336
           SV + S+   +  +   S    P+ + V   + A   C A G+P  T+ W   G R    
Sbjct: 8   SVSSPSSPPGVWSFSELSFITEPSDLTVLPKDPAVLDCQAHGQPPVTVRWLKNGVRLA-- 65

Query: 337 PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV-RGKLTVTSDDD- 394
                ++ H       + +  I  T++        C + N  G+    R  LT+    + 
Sbjct: 66  ---ESERVHFLPN-GSLYIPKIKHTEEESDEGFYQCLSQNKYGAILSQRSHLTIARISEF 121

Query: 395 --RP-PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDG 450
              P P ++T G         S+A F C    +P   I W F   AL +   R  V  +G
Sbjct: 122 VLHPVPAVVTEG---------SVARFSCVVTSSPPATITWEFNQNALAVHTERITVLPNG 172

Query: 451 TLVLKDLDKSDSGTYTCVASS 471
            L + ++   D+G Y CVA++
Sbjct: 173 VLQIHNVRPEDAGQYRCVAAN 193



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 4/75 (5%)

Query: 404 PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL----DK 459
           PS+ T+  K  AV  C A   P   + W   G  L ++ R +   +G+L +  +    ++
Sbjct: 30  PSDLTVLPKDPAVLDCQAHGQPPVTVRWLKNGVRLAESERVHFLPNGSLYIPKIKHTEEE 89

Query: 460 SDSGTYTCVASSRHG 474
           SD G Y C++ +++G
Sbjct: 90  SDEGFYQCLSQNKYG 104



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 50/214 (23%), Positives = 81/214 (37%), Gaps = 24/214 (11%)

Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
           P I   P +V           C ATG P P + WS   ++ I       D Y+A  + +G
Sbjct: 245 PRILAGPQNVTASLHQTVVLECLATGNPSPIISWSRADSKAI-------DVYNAKVLGNG 297

Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSF--VRGKLTVT-SDDDRPPPII-----TNGP 404
              L I D     S    +C A      ++      LTV  +++ R   ++     TN P
Sbjct: 298 --NLVIADVSSKHS-GVYLCRATTPGTRNYTVAAANLTVQGTENSREATLVLFLQPTNQP 354

Query: 405 SNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGT 464
           ++ ++P  S+   P +          +  + E + ++          LV+  +   D   
Sbjct: 355 TSVSVP-PSIVERPESQTRPRAGTARFMCQAEGVPRHASAGSRMGSKLVITQIIPEDDAI 413

Query: 465 YTCVASSRHGKYVWSGALLV----DSPINP-NIH 493
           Y C+A S  G  +    L+V    D P  P NIH
Sbjct: 414 YQCLAESEEGSVLSLARLIVVMSEDRPSAPRNIH 447


>UniRef50_A4JYL6 Cluster: Sid4; n=4; Clupeocephala|Rep: Sid4 - Danio
           rerio (Zebrafish) (Brachydanio rerio)
          Length = 381

 Score =  107 bits (258), Expect = 1e-21
 Identities = 101/367 (27%), Positives = 145/367 (39%), Gaps = 27/367 (7%)

Query: 112 LEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK-NGQTLLFDGDSRMHLVDGGNLVIQDA 170
           + P +     G+TV  +C    G+    + W+K N Q L   GD+     DG  L I + 
Sbjct: 26  VRPRTAAVRLGETVSFQCRVTSGAQPVMLEWRKINNQPL---GDNVKIGPDGAVLTIANV 82

Query: 171 RQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED-VVAQTGSSVTFQCRVGGDP 229
           R  + G Y+CIA NA G + +  A L +   P +   P   +  + G  VT  C V G P
Sbjct: 83  RLNNQGGYRCIATNAQG-KSTVTANLSVKHPPKVRVSPAGPLTLRVGEIVTLDCSVSGKP 141

Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
            P V W R   GG   L         SL++      + G Y C A+N  G       L +
Sbjct: 142 RPSVSWIRRQAGGETELVSTTTDSTTSLQVTMATAENAGMYVCRAQNGEGLAEGEVELVM 201

Query: 290 YDP--PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
                P  ++S   +    G      C A+G P   + WS      +  P   + K    
Sbjct: 202 EGGAFPQASVSETELTAVEGQSVSMHCQASGSPAAVLSWS-----KLRAPLPWQHKV--- 253

Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407
              DG T LT+++  + DS    +C+A +  G S    +L V S     PP  T      
Sbjct: 254 ---DGGT-LTLSNVGRQDS-GQYICNATSALGFSEAYVQLEVDS-----PPYATVLTEVV 303

Query: 408 TLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
            L +       C A  +      W   G A +     + T DG L +  L  SDSGTY C
Sbjct: 304 VLRVGDALRLQCLAHGSHPIRFRWMRVGGACMSTGAES-TKDGLLRIPQLKSSDSGTYKC 362

Query: 468 VASSRHG 474
            A++  G
Sbjct: 363 TATNHVG 369



 Score = 94.7 bits (225), Expect = 1e-17
 Identities = 102/387 (26%), Positives = 159/387 (41%), Gaps = 34/387 (8%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGGLFF 68
           +AP +  +P    V   +  +  CR      P  + W K     + D  + I P G +  
Sbjct: 20  QAPSVSVRPRTAAVRLGETVSFQCRVTSGAQPVMLEWRKINNQPLGDNVK-IGPDGAV-- 76

Query: 69  LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQ-GDTVV 126
           L   + R+++  G Y C ATN+ G +     T +++V    + R+ P    + + G+ V 
Sbjct: 77  LTIANVRLNNQGG-YRCIATNAQGKS---TVTANLSVKHPPKVRVSPAGPLTLRVGEIVT 132

Query: 127 LECLPPRGSPEPNVYW---KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
           L+C    G P P+V W   +  G+T L    +        +L +  A   +AG Y C A+
Sbjct: 133 LDC-SVSGKPRPSVSWIRRQAGGETELVSTTTDSTT----SLQVTMATAENAGMYVCRAQ 187

Query: 184 NAAGTRESAIA-TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
           N  G  E  +   ++    P       ++ A  G SV+  C+  G P   + W +     
Sbjct: 188 NGEGLAEGEVELVMEGGAFPQASVSETELTAVEGQSVSMHCQASGSPAAVLSWSKLRA-- 245

Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
             PL     +D G+L L NV   D G+Y C A +++G   A   L V  PP   +    V
Sbjct: 246 --PLPWQHKVDGGTLTLSNVGRQDSGQYICNATSALGFSEAYVQLEVDSPPYATVLTEVV 303

Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
            +  G+  R  C A G       W   G        MS     A +  DG  +L I    
Sbjct: 304 VLRVGDALRLQCLAHGSHPIRFRWMRVGGAC-----MSTG---AESTKDG--LLRIPQLK 353

Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTV 389
            +DS  T  C+A N+ GSS    ++TV
Sbjct: 354 SSDS-GTYKCTATNHVGSSEALSRVTV 379



 Score = 46.0 bits (104), Expect = 0.006
 Identities = 48/184 (26%), Positives = 77/184 (41%), Gaps = 15/184 (8%)

Query: 9   GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
           G  P       ++T    Q  +++C+A GSP+  + W K     +   H+     GG   
Sbjct: 204 GAFPQASVSETELTAVEGQSVSMHCQASGSPAAVLSWSKLRA-PLPWQHK---VDGGTLT 259

Query: 69  LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEF-RLEPESKQSAQGDTVVL 127
           L +  GR   D+G Y C AT++ G +    A + + V    +  +  E      GD + L
Sbjct: 260 L-SNVGR--QDSGQYICNATSALGFS---EAYVQLEVDSPPYATVLTEVVVLRVGDALRL 313

Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
           +CL   GS      W + G   +  G         G L I   + +D+G Y+C A N  G
Sbjct: 314 QCL-AHGSHPIRFRWMRVGGACMSTG---AESTKDGLLRIPQLKSSDSGTYKCTATNHVG 369

Query: 188 TRES 191
           + E+
Sbjct: 370 SSEA 373



 Score = 45.2 bits (102), Expect = 0.011
 Identities = 53/237 (22%), Positives = 88/237 (37%), Gaps = 19/237 (8%)

Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMF-WSVEGNRTIIFPGMSRDKYHATAVFD 351
           PS+++ P +  V  G    F C  T   +P M  W    N+ +       D        D
Sbjct: 22  PSVSVRPRTAAVRLGETVSFQCRVTSGAQPVMLEWRKINNQPL------GDNVKIGP--D 73

Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
           G  VLTI +   N+ +    C A N  G S V   L+V      PP +  +     TL +
Sbjct: 74  GA-VLTIANVRLNN-QGGYRCIATNAQGKSTVTANLSVK----HPPKVRVSPAGPLTLRV 127

Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT--LVLKDLDKSDSGTYTCVA 469
             +    C+    P P ++W    +A  +    + T D T  L +      ++G Y C A
Sbjct: 128 GEIVTLDCSVSGKPRPSVSW-IRRQAGGETELVSTTTDSTTSLQVTMATAENAGMYVCRA 186

Query: 470 SSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQ 526
            +  G       L+++    P        +++++ G             +  LSWS+
Sbjct: 187 QNGEGLAEGEVELVMEGGAFPQAS-VSETELTAVEGQSVSMHCQASGSPAAVLSWSK 242


>UniRef50_UPI0000E472F4 Cluster: PREDICTED: similar to SEC14 and
            spectrin domains 1; n=3; Strongylocentrotus
            purpuratus|Rep: PREDICTED: similar to SEC14 and spectrin
            domains 1 - Strongylocentrotus purpuratus
          Length = 3464

 Score =  107 bits (256), Expect = 2e-21
 Identities = 136/551 (24%), Positives = 214/551 (38%), Gaps = 67/551 (12%)

Query: 9    GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
            G APY   +  D  V + +   L+C   G P+P + W+K GV V +  +  +        
Sbjct: 2418 GYAPYFTRKIRDNLVKQGRATQLDCVVKGDPAPEVEWFKDGVPVRTSNNLRVECGDAGIC 2477

Query: 69   LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE--------------- 113
              + +      AGVY  +A N  G A  + A LHV  ++EEF L                
Sbjct: 2478 ALSFYNTQPEAAGVYSIKAFNVIGEAVCK-AELHVQAVQEEFVLPKEVPKVSTGHIKLTH 2536

Query: 114  ----------PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG 163
                      P  K   +G  ++LE +     P+PNV W K+G  +   G+  +  VD  
Sbjct: 2537 NATMPKFIEIPGDKNVEEGKPLILE-VTVDAYPQPNVVWSKDG--IKVKGEPYILKVDKK 2593

Query: 164  N--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK---PYLITGPEDVVAQTGSS 218
               L+I +A   D G + C A N AG R   I  +K++     P  +T   +  A+ G+ 
Sbjct: 2594 THTLIIPEADLEDEGIFICTATNPAG-RAECIIQVKVNEAEEPPVFLTPLVNAQAKKGTP 2652

Query: 219  VTFQCRVGGDPLPDVLWRRS---AGGGNMPLGRVKVLDDGSLRL--DNVILADEGEYSCE 273
              F+C + GDP+P V W ++       N      +  + G  RL  D V   D   YSC 
Sbjct: 2653 FAFECVLKGDPVPVVEWLKNNKPVKEENPDYNLKRNTETGVCRLEIDEVFPEDAARYSCR 2712

Query: 274  AENSVGAVSASGYLTVYD-------PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326
            A N  G    +  L+V          P I   P  + ++ G+  R TC   G    ++ W
Sbjct: 2713 ATNEAGKAETTCMLSVMGLDDDDLRAPVIISHPEDMTLQEGDPIRLTCQIGGELPLSVNW 2772

Query: 327  SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
              E +  +   G     +      +G+ VL +N++   D      C A N  G +     
Sbjct: 2773 FKE-DEALDEAGEFLMTFDDQ---EGLAVLKVNESFAEDE-GVYTCQATNAWGRTASSAN 2827

Query: 387  L-TVTSDDDRPPPIITNGPSNQTLPIKSMAV-------FPCTAICTPE---PIIAWYFEG 435
            L  VT+ D+         P ++   I S           P    C  +   PI A +++G
Sbjct: 2828 LIVVTAVDEIDAAAADVSPKHEAACILSKLENVTVQEGAPFKLACVVDGIAPITAQWYKG 2887

Query: 436  EALIQNHRRNV----TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPN 491
            E  +      V    +N  TL + +    DSG YTC  ++  G    S  + V    +P 
Sbjct: 2888 EEALDEGYEYVMKFQSNMATLHVNESFPEDSGMYTCRVTNAIGSDESSAQVTVLEDSSPT 2947

Query: 492  IHFFRAADVSS 502
              + +   + S
Sbjct: 2948 APWIQPLKLES 2958



 Score =   99 bits (238), Expect = 4e-19
 Identities = 120/502 (23%), Positives = 187/502 (37%), Gaps = 50/502 (9%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P  IE P D  V   +P  L       P P + W K G+ V  + +  IL          
Sbjct: 2541 PKFIEIPGDKNVEEGKPLILEVTVDAYPQPNVVWSKDGIKVKGEPY--ILKVDKKTHTLI 2598

Query: 72   THGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
                   D G++ C ATN  G A       ++ A     F     + Q+ +G     EC+
Sbjct: 2599 IPEADLEDEGIFICTATNPAGRAECIIQVKVNEAEEPPVFLTPLVNAQAKKGTPFAFECV 2658

Query: 131  PPRGSPEPNVYWKKNGQTLLF---DGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAA 186
              +G P P V W KN + +     D + + +   G   L I +    DA RY C A N A
Sbjct: 2659 L-KGDPVPVVEWLKNNKPVKEENPDYNLKRNTETGVCRLEIDEVFPEDAARYSCRATNEA 2717

Query: 187  GTRESAIATLKIHIK------PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
            G  E+      + +       P +I+ PED+  Q G  +   C++GG+    V W +   
Sbjct: 2718 GKAETTCMLSVMGLDDDDLRAPVIISHPEDMTLQEGDPIRLTCQIGGELPLSVNWFKEDE 2777

Query: 241  GGNMPLGRVKVLDD----GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV------Y 290
              +     +   DD      L+++     DEG Y+C+A N+ G  ++S  L V       
Sbjct: 2778 ALDEAGEFLMTFDDQEGLAVLKVNESFAEDEGVYTCQATNAWGRTASSANLIVVTAVDEI 2837

Query: 291  DPPSINLSP-----------NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGM 339
            D  + ++SP            +V V+ G   +  C   G    T  W  +G   +     
Sbjct: 2838 DAAAADVSPKHEAACILSKLENVTVQEGAPFKLACVVDGIAPITAQW-YKGEEAL----- 2891

Query: 340  SRDKYHATAVF-DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398
              + Y     F   +  L +N++   DS     C   N  GS     ++TV  D     P
Sbjct: 2892 -DEGYEYVMKFQSNMATLHVNESFPEDS-GMYTCRVTNAIGSDESSAQVTVLEDSSPTAP 2949

Query: 399  II--TNGPSNQ-TLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLK 455
             I      SN   + +             PEP + W+ +   L  + R  V  + T    
Sbjct: 2950 WIQPLKLESNSLEITVGQPIKLAFKVSGNPEPTVTWHHDDRPLRPDGRIKVVKEDTTYTM 3009

Query: 456  DLDKS---DSGTYTCVASSRHG 474
             + +S   D+G YT  A +  G
Sbjct: 3010 QISRSEPDDTGKYTIRAENESG 3031



 Score = 65.3 bits (152), Expect = 1e-08
 Identities = 74/304 (24%), Positives = 124/304 (40%), Gaps = 35/304 (11%)

Query: 11   APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGLFF 68
            AP II  P D+T+    P  L C+ GG    ++ W+K    +    +   +     GL  
Sbjct: 2738 APVIISHPEDMTLQEGDPIRLTCQIGGELPLSVNWFKEDEALDEAGEFLMTFDDQEGLAV 2797

Query: 69   LRATHGRVHSDAGVYWCEATNSYG-TARSRNATLHVAVLREEFR---LEPESKQSA---- 120
            L+        D GVY C+ATN++G TA S N  +  AV   +     + P+ + +     
Sbjct: 2798 LKVNESFAE-DEGVYTCQATNAWGRTASSANLIVVTAVDEIDAAAADVSPKHEAACILSK 2856

Query: 121  -------QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDAR 171
                   +G    L C+    +P    ++K  G+  L +G   +         L + ++ 
Sbjct: 2857 LENVTVQEGAPFKLACVVDGIAPITAQWYK--GEEALDEGYEYVMKFQSNMATLHVNESF 2914

Query: 172  QTDAGRYQCIARNAAGTRESAIATLKIH--------IKPYLITGPEDVVAQTGSSVTFQC 223
              D+G Y C   NA G+ ES+     +         I+P  +     +    G  +    
Sbjct: 2915 PEDSGMYTCRVTNAIGSDESSAQVTVLEDSSPTAPWIQPLKLES-NSLEITVGQPIKLAF 2973

Query: 224  RVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGA 280
            +V G+P P V W         P GR+KV+ + +   +++      D G+Y+  AEN  G 
Sbjct: 2974 KVSGNPEPTVTWHHD-DRPLRPDGRIKVVKEDTTYTMQISRSEPDDTGKYTIRAENESGH 3032

Query: 281  VSAS 284
             S+S
Sbjct: 3033 ESSS 3036



 Score = 64.5 bits (150), Expect = 2e-08
 Identities = 81/359 (22%), Positives = 126/359 (35%), Gaps = 40/359 (11%)

Query: 6    VTSGEAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
            V   E P +   PL +    +  P    C   G P P + W K    V  +     L   
Sbjct: 2629 VNEAEEPPVFLTPLVNAQAKKGTPFAFECVLKGDPVPVVEWLKNNKPVKEENPDYNLKRN 2688

Query: 65   ---GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL-----EPES 116
               G+  L         DA  Y C ATN  G A +      + +  ++ R       PE 
Sbjct: 2689 TETGVCRLEIDE-VFPEDAARYSCRATNEAGKAETTCMLSVMGLDDDDLRAPVIISHPED 2747

Query: 117  KQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT--- 173
                +GD + L C    G    +V W K  + L   G+  M   D   L +    ++   
Sbjct: 2748 MTLQEGDPIRLTC-QIGGELPLSVNWFKEDEALDEAGEFLMTFDDQEGLAVLKVNESFAE 2806

Query: 174  DAGRYQCIARNAAGTRESAIATLKI----------------HIKPYLITGPEDVVAQTGS 217
            D G Y C A NA G   S+   + +                H    +++  E+V  Q G+
Sbjct: 2807 DEGVYTCQATNAWGRTASSANLIVVTAVDEIDAAAADVSPKHEAACILSKLENVTVQEGA 2866

Query: 218  SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD--GSLRLDNVILADEGEYSCEAE 275
                 C V G       W +     +     V        +L ++     D G Y+C   
Sbjct: 2867 PFKLACVVDGIAPITAQWYKGEEALDEGYEYVMKFQSNMATLHVNESFPEDSGMYTCRVT 2926

Query: 276  NSVGAVSASGYLTVYDPPS--------INLSPNSVNVESGNVARFTCTATGRPEPTMFW 326
            N++G+  +S  +TV +  S        + L  NS+ +  G   +     +G PEPT+ W
Sbjct: 2927 NAIGSDESSAQVTVLEDSSPTAPWIQPLKLESNSLEITVGQPIKLAFKVSGNPEPTVTW 2985



 Score = 54.0 bits (124), Expect = 2e-05
 Identities = 52/179 (29%), Positives = 74/179 (41%), Gaps = 17/179 (9%)

Query: 124  TVVLECLPPRGSPEPNVYWKKNGQTLLFDG-----DSRMHLVDGGN---LVIQDARQTDA 175
            TVV E    RG+   N+    +G    F+        R+  V  G+   LVI+     DA
Sbjct: 3287 TVVAE--NERGTETVNIVINVSGVQWFFNNTPIQPSDRVEFVRDGDVYYLVIKRPTSGDA 3344

Query: 176  GRYQCIARNAAGTRESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233
            G YQC A        +   T+ ++ K  P  I   E VVA  GS++  +CR+ G P P V
Sbjct: 3345 GLYQCRAETEVSVVTTE-CTIMVNDKQSPDFIAPLESVVASEGSTIRLECRMSGSPAPTV 3403

Query: 234  LWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
             W +          RV+ L +G    L +  V  +D G Y     N  G   +S  L +
Sbjct: 3404 KWTKDE-RSITETSRVRFLTEGDRQILMIIQVRPSDAGNYRITLTNDFGVSVSSATLLI 3461



 Score = 53.6 bits (123), Expect = 3e-05
 Identities = 52/202 (25%), Positives = 82/202 (40%), Gaps = 16/202 (7%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            EA  I+ +  +VTV    P  L C   G      +WYKG    + + +  ++        
Sbjct: 2849 EAACILSKLENVTVQEGAPFKLACVVDGIAPITAQWYKGEE-ALDEGYEYVMKFQSNMAT 2907

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE---------FRLEPESKQSA 120
               +     D+G+Y C  TN+ G   S  ++  V VL +           +LE  S +  
Sbjct: 2908 LHVNESFPEDSGMYTCRVTNAIG---SDESSAQVTVLEDSSPTAPWIQPLKLESNSLEIT 2964

Query: 121  QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQ 179
             G  + L      G+PEP V W  + + L  DG  ++   D    + I  +   D G+Y 
Sbjct: 2965 VGQPIKL-AFKVSGNPEPTVTWHHDDRPLRPDGRIKVVKEDTTYTMQISRSEPDDTGKYT 3023

Query: 180  CIARNAAGTRESAIATLKIHIK 201
              A N +G  ES+    K+ IK
Sbjct: 3024 IRAENESG-HESSSTDYKLVIK 3044



 Score = 46.8 bits (106), Expect = 0.004
 Identities = 45/176 (25%), Positives = 72/176 (40%), Gaps = 8/176 (4%)

Query: 20   DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
            D+ V+  +P  +  R  G P+P I WYK    +       +     +  L      +  D
Sbjct: 3122 DIEVSEGEPIEIAIRVTGQPAPRITWYKDDEPINGKPQYEMSFVESVARLDVREAFL-ED 3180

Query: 80   AGVYWCEATNSYG-TARSRNATLHV-AVLREEFRLEPESKQSAQGDTVVLECL----PPR 133
             G Y C+ATN  G    +   T++V A L     + P   Q +  D  V + +      R
Sbjct: 3181 EGRYVCKATNPAGQDTTTCQITVNVNAALTPAPHVVPLQTQFSHLDIPVGQPIRLHFRIR 3240

Query: 134  GSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGT 188
            G P P V W +N   ++   +  +   +    LVI++ R    G+Y  +A N  GT
Sbjct: 3241 GQPPPKVTWLQNDVEIVETEEVEIIKEETVHTLVIKNPRPDAGGKYTVVAENERGT 3296



 Score = 42.7 bits (96), Expect = 0.059
 Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 5/88 (5%)

Query: 245  PLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN-LSP- 299
            P  RV+ + DG    L +      D G Y C AE  V  V+    + V D  S + ++P 
Sbjct: 3319 PSDRVEFVRDGDVYYLVIKRPTSGDAGLYQCRAETEVSVVTTECTIMVNDKQSPDFIAPL 3378

Query: 300  NSVNVESGNVARFTCTATGRPEPTMFWS 327
             SV    G+  R  C  +G P PT+ W+
Sbjct: 3379 ESVVASEGSTIRLECRMSGSPAPTVKWT 3406



 Score = 41.5 bits (93), Expect = 0.14
 Identities = 34/150 (22%), Positives = 58/150 (38%), Gaps = 11/150 (7%)

Query: 188  TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
            T+  A+  +   + P   +  +D+    G  +    RV G P P + W +     N    
Sbjct: 3100 TQPDAMPVMGAAMPPRFQSRLKDIEVSEGEPIEIAIRVTGQPAPRITWYKDDEPINGKPQ 3159

Query: 248  RVKVLDDGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
                  +   RLD     L DEG Y C+A N  G  + +  +TV    ++  +P+ V ++
Sbjct: 3160 YEMSFVESVARLDVREAFLEDEGRYVCKATNPAGQDTTTCQITVNVNAALTPAPHVVPLQ 3219

Query: 306  S---------GNVARFTCTATGRPEPTMFW 326
            +         G   R      G+P P + W
Sbjct: 3220 TQFSHLDIPVGQPIRLHFRIRGQPPPKVTW 3249



 Score = 41.1 bits (92), Expect = 0.18
 Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 2/96 (2%)

Query: 6    VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
            V   ++P  I     V  +      L CR  GSP+P ++W K    +   +    L  G 
Sbjct: 3366 VNDKQSPDFIAPLESVVASEGSTIRLECRMSGSPAPTVKWTKDERSITETSRVRFLTEGD 3425

Query: 66   LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATL 101
               L     R  SDAG Y    TN +G + S +ATL
Sbjct: 3426 RQILMIIQVR-PSDAGNYRITLTNDFGVSVS-SATL 3459



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 41/191 (21%), Positives = 67/191 (35%), Gaps = 16/191 (8%)

Query: 292  PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
            PP        + V  G         TG+P P + W  +       P   + +Y  + V +
Sbjct: 3113 PPRFQSRLKDIEVSEGEPIEIAIRVTGQPAPRITWYKDDE-----PINGKPQYEMSFV-E 3166

Query: 352  GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP-----PIITNGPSN 406
             V  L + +    D     VC A N AG      ++TV  +    P     P+ T   S+
Sbjct: 3167 SVARLDVREAFLEDE-GRYVCKATNPAGQDTTTCQITVNVNAALTPAPHVVPLQTQF-SH 3224

Query: 407  QTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSG 463
              +P+             P P + W      +++     +  + T   LV+K+      G
Sbjct: 3225 LDIPVGQPIRLHFRIRGQPPPKVTWLQNDVEIVETEEVEIIKEETVHTLVIKNPRPDAGG 3284

Query: 464  TYTCVASSRHG 474
             YT VA +  G
Sbjct: 3285 KYTVVAENERG 3295


>UniRef50_UPI00004D1686 Cluster: Neogenin precursor.; n=1; Xenopus
           tropicalis|Rep: Neogenin precursor. - Xenopus tropicalis
          Length = 918

 Score =  107 bits (256), Expect = 2e-21
 Identities = 78/224 (34%), Positives = 111/224 (49%), Gaps = 23/224 (10%)

Query: 29  ATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGLFFLRATHGRVHS-DAGVYWC 85
           A LNC A   P+P I W K G  +  VSD  R +LP G L      H + +  D G+Y C
Sbjct: 2   AVLNCSAYADPTPKIEWKKDGTFLNLVSDDRRRLLPDGSLLITSVVHSKHNKPDEGIYQC 61

Query: 86  EAT-NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE--PNVYW 142
            AT  S G+  SR A L VA L   F  +PES     GD++VL C     SPE  P V+W
Sbjct: 62  VATVESLGSIVSRTARLSVAGL-PRFTSQPESSSVYVGDSIVLNC---DVSPELVPFVHW 117

Query: 143 KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI-HIK 201
           ++N  +   + D+R+ ++  G+LVI +A ++DAG Y+C     +  + S  A +++   K
Sbjct: 118 EQNKASR--ELDNRVAVLLNGSLVISNANESDAGLYRCAVGGGSSIKYSEEAEIRVLQGK 175

Query: 202 PYLITG----------PEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
            +L TG          P  +   +G +    C V G P P V W
Sbjct: 176 FFLDTGDERPMLFLRQPLPLTRVSGQTALLTCVVSGYPTPSVRW 219



 Score = 93.5 bits (222), Expect = 3e-17
 Identities = 122/580 (21%), Positives = 224/580 (38%), Gaps = 56/580 (9%)

Query: 218 SVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNVILA-----DEGEYS 271
           +    C    DP P + W++     N+    R ++L DGSL + +V+ +     DEG Y 
Sbjct: 1   AAVLNCSAYADPTPKIEWKKDGTFLNLVSDDRRRLLPDGSLLITSVVHSKHNKPDEGIYQ 60

Query: 272 CEAE-NSVGA-VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVE 329
           C A   S+G+ VS +  L+V   P     P S +V  G+     C  +    P + W  E
Sbjct: 61  CVATVESLGSIVSRTARLSVAGLPRFTSQPESSSVYVGDSIVLNCDVSPELVPFVHW--E 118

Query: 330 GNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC-SAVNYAGSSFVR---G 385
            N+         D   A  +   + +   N++D    R  +   S++ Y+  + +R   G
Sbjct: 119 QNKA----SRELDNRVAVLLNGSLVISNANESDAGLYRCAVGGGSSIKYSEEAEIRVLQG 174

Query: 386 KLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN 445
           K  + + D+RP  +    P   T      A+  C     P P + W    + ++   R  
Sbjct: 175 KFFLDTGDERPM-LFLRQPLPLTRVSGQTALLTCVVSGYPTPSVRWTHNQKEILTEKRTM 233

Query: 446 VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPG 505
                  +L +    + G   C            G  +  SP  P++    A +V++ PG
Sbjct: 234 TCRCLVWLLGNSGLPEVGQQ-C-----------QGVTIPTSP-TPSLTRATAHNVAATPG 280

Query: 506 PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565
            P      N T T       +     + ++L   + + + +    +  P+  R  +V A 
Sbjct: 281 GPLPSSPRNSTCTCTGKQKKKKKSRLAVNMLRLALALANPDQTKQSVKPQ--RSVLVSAV 338

Query: 566 RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV------------TVGDDSNS 613
              +  +   S  P  T+      E     S P  +  ++             V  + N 
Sbjct: 339 LASRVAFAGNSSAPAYTFSNNNPMERVENTSRPGEMQVTIQNLLPETVYYFRVVAQNQNG 398

Query: 614 LWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWE--ILNFYYLEGLFIYF--R 669
             E + +    E +  +         +ATP+   ++ + WE  +     ++   +Y+  +
Sbjct: 399 AGESS-LPLKVETQPEVQVPGPAPNFKATPVSPTSVSVSWETPLSGNGEIQSYKLYYMEK 457

Query: 670 PLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDD 729
             DN  + +  K       V   ++  L+KYT+Y F ++ F K   G  +     +TL D
Sbjct: 458 GADNEQVRWRFK-----EGVVILKVNGLKKYTEYTFRVVAFNKHGPGVSTQDVTVRTLSD 512

Query: 730 VPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNV 769
           VP   P N+ + + ++ ++ ++W PP +  QNG I GY V
Sbjct: 513 VPSAAPQNLTLEVRSSQSILVQWQPPPIGSQNGQIVGYKV 552



 Score = 79.0 bits (186), Expect = 7e-13
 Identities = 63/220 (28%), Positives = 92/220 (41%), Gaps = 20/220 (9%)

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA-----RQTDAGRYQC 180
           VL C      P P + WKK+G  L    D R  L+  G+L+I         + D G YQC
Sbjct: 3   VLNC-SAYADPTPKIEWKKDGTFLNLVSDDRRRLLPDGSLLITSVVHSKHNKPDEGIYQC 61

Query: 181 IAR-NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
           +A   + G+  S  A L +   P   + PE      G S+   C V  + +P V W ++ 
Sbjct: 62  VATVESLGSIVSRTARLSVAGLPRFTSQPESSSVYVGDSIVLNCDVSPELVPFVHWEQNK 121

Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSC----------EAENSVGAVSASGYLTV 289
               +   RV VL +GSL + N   +D G Y C            E  +  +    +L  
Sbjct: 122 ASRELD-NRVAVLLNGSLVISNANESDAGLYRCAVGGGSSIKYSEEAEIRVLQGKFFLDT 180

Query: 290 YDP-PSINL-SPNSVNVESGNVARFTCTATGRPEPTMFWS 327
            D  P + L  P  +   SG  A  TC  +G P P++ W+
Sbjct: 181 GDERPMLFLRQPLPLTRVSGQTALLTCVVSGYPTPSVRWT 220



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 37/149 (24%), Positives = 52/149 (34%), Gaps = 15/149 (10%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P    QP   +V       LNC       P + W +       D   ++L  G L    A
Sbjct: 84  PRFTSQPESSSVYVGDSIVLNCDVSPELVPFVHWEQNKASRELDNRVAVLLNGSLVISNA 143

Query: 72  THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR------EE----FRLEPESKQSAQ 121
                 SDAG+Y C          S  A + V   +      +E    F  +P       
Sbjct: 144 N----ESDAGLYRCAVGGGSSIKYSEEAEIRVLQGKFFLDTGDERPMLFLRQPLPLTRVS 199

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
           G T +L C+   G P P+V W  N + +L
Sbjct: 200 GQTALLTCV-VSGYPTPSVRWTHNQKEIL 227



 Score = 35.5 bits (78), Expect = 8.9
 Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 1/40 (2%)

Query: 7   TSGEAPYI-IEQPLDVTVARHQPATLNCRAGGSPSPAIRW 45
           T  E P + + QPL +T    Q A L C   G P+P++RW
Sbjct: 180 TGDERPMLFLRQPLPLTRVSGQTALLTCVVSGYPTPSVRW 219


>UniRef50_Q4RKK6 Cluster: Chromosome 5 SCAF15028, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 5 SCAF15028, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 875

 Score =  107 bits (256), Expect = 2e-21
 Identities = 90/283 (31%), Positives = 124/283 (43%), Gaps = 22/283 (7%)

Query: 17  QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI-LPAGGLFFLRATHGR 75
           +P   T+     A   C+  G P+P I W K  V V  +T   I LP GGL  L  T   
Sbjct: 7   EPSPQTIPLGGAARFECQIEGVPTPTIMWEKDRVAVPEETSSFISLPNGGLQILGVTK-- 64

Query: 76  VHSDAGVYWCEATNSYGTARSRNATLHVAVLREE------FRLEPESKQSAQGDTVVLEC 129
              D G Y    +NS  T  SR A   V     E        + P +     G   V+EC
Sbjct: 65  --KDEGAYRFVLSNSASTDVSREARRTVTTDPTENLNRIVIVVPPRNTTVMLGRLAVMEC 122

Query: 130 LPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
           +   G P+P V W +++G+ +  D      +V   NLVI+D R   AG Y C A N   T
Sbjct: 123 MA-EGRPKPLVSWSRQDGKPISTDV-----VVLATNLVIRDTRSHHAGVYVCRA-NKPRT 175

Query: 189 RESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
           RE   A  ++H+   P +I  PE      G++  F C   G+P P + W ++ G      
Sbjct: 176 REFVTAAAELHVPAPPVIIQPPETASLSRGNTARFVCNSTGEPSPVLHWLKN-GQPVKSF 234

Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
            RVK    G L ++ +   D G Y C A+N +G   A+  LTV
Sbjct: 235 RRVKSQSPGVLLINQLAPEDAGYYQCIADNGLGTACATAKLTV 277



 Score = 95.9 bits (228), Expect = 6e-18
 Identities = 101/410 (24%), Positives = 154/410 (37%), Gaps = 31/410 (7%)

Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267
           P       G +  F+C++ G P P ++W +              L +G L++  V   DE
Sbjct: 8   PSPQTIPLGGAARFECQIEGVPTPTIMWEKDRVAVPEETSSFISLPNGGLQILGVTKKDE 67

Query: 268 GEYSCEAENSVGA-VSASGYLTVYDPPSINLS-------PNSVNVESGNVARFTCTATGR 319
           G Y     NS    VS     TV   P+ NL+       P +  V  G +A   C A GR
Sbjct: 68  GAYRFVLSNSASTDVSREARRTVTTDPTENLNRIVIVVPPRNTTVMLGRLAVMECMAEGR 127

Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379
           P+P + WS +  + I           +T V    T L I DT ++      VC A     
Sbjct: 128 PKPLVSWSRQDGKPI-----------STDVVVLATNLVIRDT-RSHHAGVYVCRANKPRT 175

Query: 380 SSFVRGKLTVTSDDDRP-PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438
             FV    T  ++   P PP+I   P   +L   + A F C +   P P++ W   G+ +
Sbjct: 176 REFV----TAAAELHVPAPPVIIQPPETASLSRGNTARFVCNSTGEPSPVLHWLKNGQPV 231

Query: 439 IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL--LVDSPINPNIHFFR 496
               R    + G L++  L   D+G Y C+A +  G    +  L  +V   +    H   
Sbjct: 232 KSFRRVKSQSPGVLLINQLAPEDAGYYQCIADNGLGTACATAKLTVIVREGLPSAPHHLT 291

Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETL---SGNNT 553
           A   SS     T     + +D  +  S       G   ++   +  F ++          
Sbjct: 292 ATPYSSTSALLTWEKPEHNSDQIIGYSVHCQRATGLFLVMCLWMSRFLQQAYFFWIFPTF 351

Query: 554 PRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS-PVS 602
           P +       A     T Y++K L P   Y F V   +  G S PS PV+
Sbjct: 352 PGSDNVEYQFAMNNDTTEYLIKELAPYTAYTFFVVAYSPMGASRPSVPVT 401



 Score = 90.6 bits (215), Expect = 2e-16
 Identities = 124/525 (23%), Positives = 209/525 (39%), Gaps = 44/525 (8%)

Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
           P+   +  G  ARF C   G P PT+ W  E +R  +    S      +    G+ +L +
Sbjct: 8   PSPQTIPLGGAARFECQIEGVPTPTIMW--EKDRVAVPEETSS---FISLPNGGLQILGV 62

Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
              D+   R  +  SA     S   R  +T    ++    +I   P N T+ +  +AV  
Sbjct: 63  TKKDEGAYRFVLSNSASTDV-SREARRTVTTDPTENLNRIVIVVPPRNTTVMLGRLAVME 121

Query: 419 CTAICTPEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
           C A   P+P+++W  + G+ +  +     TN   LV++D     +G Y C A+    +  
Sbjct: 122 CMAEGRPKPLVSWSRQDGKPISTDVVVLATN---LVIRDTRSHHAGVYVCRANKPRTREF 178

Query: 478 WSGALLVDSPINPNIHFFRAADVSSLP-GPPTKPITHNVTDTSVTLSWSQNNKIGSSSIL 536
            + A  +  P  P I   +  + +SL  G   + + ++  + S  L W +N +   S   
Sbjct: 179 VTAAAELHVPAPPVI--IQPPETASLSRGNTARFVCNSTGEPSPVLHWLKNGQPVKSF-- 234

Query: 537 GYQVEVFSRETLSGNN-TPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGL 595
             +V+  S   L  N   P ++  +  IA     T      L        IVR     GL
Sbjct: 235 -RRVKSQSPGVLLINQLAPEDAGYYQCIADNGLGTACATAKLT------VIVR----EGL 283

Query: 596 -SGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWE 654
            S P  ++ +      +   WE        E+ ++ +  + V    AT +       M  
Sbjct: 284 PSAPHHLTATPYSSTSALLTWE------KPEHNSDQIIGYSVHCQRATGLFLVMCLWMSR 337

Query: 655 ILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKF 714
            L   Y   +F  F   DN+  ++ M     +ND + + I  L  YT Y FF++ +    
Sbjct: 338 FLQQAYFFWIFPTFPGSDNVEYQFAM-----NNDTTEYLIKELAPYTAYTFFVVAYSPMG 392

Query: 715 EGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWL 774
             +PS     + ++DVP  PP  + +   + T + L W P   +   G +T Y +  + L
Sbjct: 393 ASRPSVPVTVEMMEDVPSSPP-QLAIASTSPTEIRLTWHPLPSERSRGTVTHYRIEYSTL 451

Query: 775 DVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819
            V  +   V +   V Q T   +  L     Y V+I+A T IG G
Sbjct: 452 -VQDSVFSVEVRGNVTQFT---LRELEPNQVYRVRISAATGIGFG 492



 Score = 70.5 bits (165), Expect = 3e-10
 Identities = 67/211 (31%), Positives = 93/211 (44%), Gaps = 18/211 (8%)

Query: 14  IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
           I+  P + TV   + A + C A G P P + W +     +S T   +L       +R T 
Sbjct: 103 IVVPPRNTTVMLGRLAVMECMAEGRPKPLVSWSRQDGKPIS-TDVVVLATN--LVIRDT- 158

Query: 74  GRVHSDAGVYWCEA----TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
            R H  AGVY C A    T  + TA    A LHV       +  PE+   ++G+T    C
Sbjct: 159 -RSH-HAGVYVCRANKPRTREFVTAA---AELHVPAPPVIIQ-PPETASLSRGNTARFVC 212

Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
               G P P ++W KNGQ +      R+     G L+I      DAG YQCIA N  GT 
Sbjct: 213 -NSTGEPSPVLHWLKNGQPV--KSFRRVKSQSPGVLLINQLAPEDAGYYQCIADNGLGT- 268

Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVT 220
             A A L + ++  L + P  + A   SS +
Sbjct: 269 ACATAKLTVIVREGLPSAPHHLTATPYSSTS 299



 Score = 54.8 bits (126), Expect = 1e-05
 Identities = 37/129 (28%), Positives = 67/129 (51%), Gaps = 3/129 (2%)

Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
           +  L+ +T+YE  +        G  S++    TL D P  PP  +++  L++++V + W 
Sbjct: 712 LEGLKPFTRYELAVQSNGADVAGPFSDTVEESTLPDRPSTPPEELQLNPLDSSSVLVSWR 771

Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAE 813
           PP L+  NGIITGY ++ +  ++     +    +     TS+ +  L+SG  Y  ++ A 
Sbjct: 772 PP-LE-PNGIITGYFILYSG-NLSQPDDLWEKLSQDGSITSVEVQGLSSGTHYFFKLGAA 828

Query: 814 TIIGLGPFS 822
           T +G GP+S
Sbjct: 829 TEVGPGPYS 837



 Score = 44.8 bits (101), Expect = 0.015
 Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 4/83 (4%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P II+ P   +++R   A   C + G PSP + W K G  V S   R    + G+  +  
Sbjct: 191 PVIIQPPETASLSRGNTARFVCNSTGEPSPVLHWLKNGQPVKS-FRRVKSQSPGVLLINQ 249

Query: 72  THGRVHSDAGVYWCEATNSYGTA 94
                  DAG Y C A N  GTA
Sbjct: 250 L---APEDAGYYQCIADNGLGTA 269


>UniRef50_Q7Q0S6 Cluster: ENSANGP00000006166; n=5; cellular
           organisms|Rep: ENSANGP00000006166 - Anopheles gambiae
           str. PEST
          Length = 1286

 Score =  107 bits (256), Expect = 2e-21
 Identities = 129/492 (26%), Positives = 191/492 (38%), Gaps = 69/492 (14%)

Query: 16  EQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74
           E PL  +V R Q A L C     P P  ++W + G  + S    +I            H 
Sbjct: 232 ENPL--SVERDQTAKLECNIDAKPKPEQVKWTRNGRFISSHPTHTI------------HR 277

Query: 75  RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRG 134
               DAG Y C A N       +  TL+V +     ++E ++K + + +TV ++C     
Sbjct: 278 VSLQDAGRYTCSADNGLDKIGEQEITLNV-LYPPIVQIETKAKTAEEKETVHIKCNVTAN 336

Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN-----AAGTR 189
            P   + W K G     D D R +   G  LV++D R  DAG Y C   N        T 
Sbjct: 337 PPPVTIEWLKEG-----DIDFRRN---GDTLVLRDVRAEDAGTYICRGINMMKPYGGKTL 388

Query: 190 E----SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVG--GDPLPDVLWRRSAGGGN 243
           E    +++A L  H     +  PE  V   G+SV+  C+    G P P   W R  GG  
Sbjct: 389 EREGNASVALLVRHRPGQAVITPEKPVVHVGNSVSLMCKADPPGYPDPQYRWYRDVGG-- 446

Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSPNSV 302
             +    +       +    L+ EG+Y C A N +G    AS  L ++ PP       S 
Sbjct: 447 -EVSTTVIAQGAQYLIPKAALSSEGKYHCHASNELGNGGMASATLEIHQPPQFLAKLQSN 505

Query: 303 NVESGNVARF--TCTATGRPEPTMFW-------SVEGNRTIIFPGMSRDKYHATAV---- 349
            ++    A F  TC+A G+PEP++ W       + E +R  +   + +       V    
Sbjct: 506 MIKRAGEADFFVTCSAKGKPEPSITWLKDDVEITPELHRYEVKTNVDKGPNGMVTVQSML 565

Query: 350 -FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408
            F G      ND    D R    C   N    +     L +  +     PI+ +  +   
Sbjct: 566 KFTGKARPNGNDLISTD-RGQYTCLYENEVNKANSTMHLKIEHE-----PIVLHQYNKVA 619

Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ--NHRRNVTN-DG----TLVLK--DLDK 459
             IK  A   C     P+P   W+F G  L+    H   +TN DG    T +LK  ++  
Sbjct: 620 NDIKETAEVLCKVQSYPKPEFLWHF-GTTLLSTGGHYEIITNSDGNDVYTSILKISNVRH 678

Query: 460 SDSGTYTCVASS 471
            D G Y C  S+
Sbjct: 679 QDYGEYHCRVSN 690



 Score = 62.1 bits (144), Expect = 9e-08
 Identities = 70/308 (22%), Positives = 115/308 (37%), Gaps = 39/308 (12%)

Query: 30  TLNCRAG--GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEA 87
           +L C+A   G P P  RWY+    V  +   +++  G  + +        S  G Y C A
Sbjct: 423 SLMCKADPPGYPDPQYRWYRD---VGGEVSTTVIAQGAQYLIPKA---ALSSEGKYHCHA 476

Query: 88  TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
           +N  G     +ATL +    +       +     G+         +G PEP++ W K+  
Sbjct: 477 SNELGNGGMASATLEIHQPPQFLAKLQSNMIKRAGEADFFVTCSAKGKPEPSITWLKDDV 536

Query: 148 TLL-----FDGDSRMHLVDGGNLVIQ--------------DARQTDAGRYQCIARNAAGT 188
            +      ++  + +     G + +Q              D   TD G+Y C+  N    
Sbjct: 537 EITPELHRYEVKTNVDKGPNGMVTVQSMLKFTGKARPNGNDLISTDRGQYTCLYENEVNK 596

Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGGGNM 244
             S +  LKI  +P ++     V      +    C+V   P P+ LW       + GG+ 
Sbjct: 597 ANSTMH-LKIEHEPIVLHQYNKVANDIKETAEVLCKVQSYPKPEFLWHFGTTLLSTGGHY 655

Query: 245 PLGRVKVLDD---GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
            +      +D     L++ NV   D GEY C   NS+  +     L    PP     PN 
Sbjct: 656 EIITNSDGNDVYTSILKISNVRHQDYGEYHCRVSNSLNHIQVPIRLQPKGPPE---KPNK 712

Query: 302 VN-VESGN 308
           +  VE G+
Sbjct: 713 LKAVELGS 720



 Score = 61.7 bits (143), Expect = 1e-07
 Identities = 103/441 (23%), Positives = 159/441 (36%), Gaps = 54/441 (12%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRA-GGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
           P +I    + T    +   L C + GGSP P I WY+ G       +   L  GG   ++
Sbjct: 124 PPLIFPGSETTATEDKKQELTCSSVGGSPDPTISWYREGSTTPLAAN---LIYGGSRDMQ 180

Query: 71  ATHG-----RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE--PESKQSAQGD 123
            T       R   D   + C   N       R  T+    +R   R+E  PE+  S + D
Sbjct: 181 TTSTLTIIPRREDDGAKFTCVVWNRAMPESQRLETVTTLSVRYYPRVEIGPENPLSVERD 240

Query: 124 -TVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
            T  LEC +  +  PE  V W +NG+ +       +H V      +QDA     GRY C 
Sbjct: 241 QTAKLECNIDAKPKPE-QVKWTRNGRFISSHPTHTIHRVS-----LQDA-----GRYTCS 289

Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRRSA- 239
           A N          TL +   P +    +   A+   +V  +C V  +P P  + W +   
Sbjct: 290 ADNGLDKIGEQEITLNVLYPPIVQIETKAKTAEEKETVHIKCNVTANPPPVTIEWLKEGD 349

Query: 240 -----GGGNMPLGRVKVLDDGSLRLDNV-ILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
                 G  + L  V+  D G+     + ++   G  + E E +    ++   L  + P 
Sbjct: 350 IDFRRNGDTLVLRDVRAEDAGTYICRGINMMKPYGGKTLEREGN----ASVALLVRHRPG 405

Query: 294 SINLSPNSVNVESGNVARFTCTA--TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
              ++P    V  GN     C A   G P+P   W  +    +            T +  
Sbjct: 406 QAVITPEKPVVHVGNSVSLMCKADPPGYPDPQYRWYRDVGGEV----------STTVIAQ 455

Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
           G   L       ++ +    C A N  G+    G  + T +  +PP  +    SN     
Sbjct: 456 GAQYLIPKAALSSEGK--YHCHASNELGNG---GMASATLEIHQPPQFLAKLQSNMIKRA 510

Query: 412 KSMAVF-PCTAICTPEPIIAW 431
                F  C+A   PEP I W
Sbjct: 511 GEADFFVTCSAKGKPEPSITW 531



 Score = 43.6 bits (98), Expect = 0.034
 Identities = 60/224 (26%), Positives = 92/224 (41%), Gaps = 22/224 (9%)

Query: 257 LRLDNVILA-DEGEYSCEAEN--SVGAVSASGY-LTVYDPPSINLS-PNSVNVESGNVAR 311
           L++ NV  A D G + C  +   S  A+    Y LTV  PP   L  P S    + +  +
Sbjct: 82  LQIFNVSYARDNGRFECRIKQIGSDNAIYEDYYNLTVLTPPQPPLIFPGSETTATEDKKQ 141

Query: 312 -FTCTATG-RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
             TC++ G  P+PT+ W  EG+ T   P  +   Y  +      + LTI    ++D    
Sbjct: 142 ELTCSSVGGSPDPTISWYREGSTT---PLAANLIYGGSRDMQTTSTLTIIPRREDDGAK- 197

Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ-TLPIKSMAVFPCTAICTPEP- 427
             C   N A     R + TVT+   R  P +  GP N  ++     A   C     P+P 
Sbjct: 198 FTCVVWNRAMPESQRLE-TVTTLSVRYYPRVEIGPENPLSVERDQTAKLECNIDAKPKPE 256

Query: 428 IIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
            + W   G        R +++  T  +  +   D+G YTC A +
Sbjct: 257 QVKWTRNG--------RFISSHPTHTIHRVSLQDAGRYTCSADN 292


>UniRef50_P23468 Cluster: Receptor-type tyrosine-protein phosphatase
           delta precursor; n=183; Eumetazoa|Rep: Receptor-type
           tyrosine-protein phosphatase delta precursor - Homo
           sapiens (Human)
          Length = 1912

 Score =  107 bits (256), Expect = 2e-21
 Identities = 156/644 (24%), Positives = 245/644 (38%), Gaps = 87/644 (13%)

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LR 258
           P     P D    +G   +F C+  GDP P ++W +     +     V   DDGS   LR
Sbjct: 24  PRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLR 83

Query: 259 LDNVILA-DEGEYSCEAENSVGAVSASGYLTVYDP-------PSINLSPNSVNVESGNVA 310
           +  +    DE  Y C A N+VG +S S  LTV          P+I++ P    VE    A
Sbjct: 84  IQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTA 143

Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV---LTINDTDKNDSR 367
              C A+G P+P + W  +           R K   +    G  +   L I  ++++D +
Sbjct: 144 TMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESD-Q 202

Query: 368 NTIVCSAVNYAGSSF-VRGKLTVTS--DDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
               C A N AG+ +     L V    +  R PP  +  P+N  +         C A+ +
Sbjct: 203 GKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGS 262

Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
           P P + W    E L       +   G  VL+  D   S  YTCVA S  G          
Sbjct: 263 PMPYVKWMLGAEDLTPEDDMPI---GRNVLELNDVRQSANYTCVAMSTLGV--------- 310

Query: 485 DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFS 544
                  I       V +LP PP  P+    T TS+TL+W   N      +  Y ++   
Sbjct: 311 -------IEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGN---PEPVSYYIIQ--- 357

Query: 545 RETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS-PVSD 603
                  + P+NS         V  T Y V  L P   Y F V   N+ G   PS PV  
Sbjct: 358 -------HKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPV-- 408

Query: 604 SVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILN--FYYL 661
                     L + +  + S+  R+          ++A  + S TI + W+        +
Sbjct: 409 ----------LTQTSEQAPSSAPRD----------VQARMLSSTTILVQWKEPEEPNGQI 448

Query: 662 EGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNS 721
           +G  +Y+       +   MK  +  + ++   I +L     Y   ++ F    +G  S+ 
Sbjct: 449 QGYRVYYTMDPTQHVNNWMKHNVADSQIT--TIGNLVPQKTYSVKVLAFTSIGDGPLSSD 506

Query: 722 RVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKS 781
               T   VP G P+N +    + T++ L W+PP    ++  I  Y +V  + D    + 
Sbjct: 507 IQVITQTGVP-GQPLNFKAEPESETSILLSWTPP----RSDTIANYELV--YKDGEHGEE 559

Query: 782 MVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
                 T+   TS  +  L     Y  ++AA +  GLG  + ++
Sbjct: 560 Q---RITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEI 600



 Score = 97.1 bits (231), Expect = 3e-18
 Identities = 94/349 (26%), Positives = 142/349 (40%), Gaps = 46/349 (13%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI-LPAGGLFFLR 70
           P     P+D T      A+  C+A G P P I W K G  V +     I    G    LR
Sbjct: 24  PRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLR 83

Query: 71  ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE--------FRLEPESKQSAQG 122
               R   D  +Y C A+N+ G     + +  + VLRE+          + P+ K   + 
Sbjct: 84  IQPLRTPRDEAIYECVASNNVGEI---SVSTRLTVLREDQIPRGFPTIDMGPQLKVVERT 140

Query: 123 DTVVLECLPPRGSPEPNVYWKK----------NGQTLLFDGDSRMHLVDGGNLVIQDARQ 172
            T  + C    G+P+P + W K          NG+      +S       G L I+ + +
Sbjct: 141 RTATMLCAAS-GNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEE 199

Query: 173 TDAGRYQCIARNAAGTRESAIATLKI-------HIKPYLITGPEDVVAQTGSSVTFQCRV 225
           +D G+Y+C+A N+AGTR SA A L +        + P     P +     G SV   C  
Sbjct: 200 SDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVA 259

Query: 226 GGDPLPDVLWRRSAGG----GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281
            G P+P V W   A       +MP+GR  VL+   +R           Y+C A +++G +
Sbjct: 260 VGSPMPYVKWMLGAEDLTPEDDMPIGR-NVLELNDVR-------QSANYTCVAMSTLGVI 311

Query: 282 SASGYLTVYDPPSINLSPNSVNVESGNVARFTCT-ATGRPEPTMFWSVE 329
            A   +TV   P     P +  V        T T  +G PEP  ++ ++
Sbjct: 312 EAIAQITVKALPK---PPGTPVVTESTATSITLTWDSGNPEPVSYYIIQ 357



 Score = 70.1 bits (164), Expect = 3e-10
 Identities = 102/422 (24%), Positives = 171/422 (40%), Gaps = 36/422 (8%)

Query: 505  GPPTKPITHNVTDTSVTLSWSQN--NKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
            GPP K     V  TSV +SW     NK     I GYQV     E       P      + 
Sbjct: 713  GPPRKVEVEAVNSTSVKVSWRSPVPNK-QHGQIRGYQVHYVRMENGEPKGQPMLKDVMLA 771

Query: 563  IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSN 622
             A+           +I G+      + E S+ L+    V+   T GD + S  +    + 
Sbjct: 772  DAQWEFDDTTEHDMIISGL------QPETSYSLT----VTAYTTKGDGARSKPKLVSTTG 821

Query: 623  STEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKT 682
            +   +  ++ +H       T +++  I+    +  F  L+G  + F   D   +E  + T
Sbjct: 822  AVPGKPRLVINH-------TQMNTALIQWHPPVDTFGPLQGYRLKFGRKD---ME-PLTT 870

Query: 683  ILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFI 742
            +  S     F  T + K   Y F L    K   G+     ++   ++VP G P N+    
Sbjct: 871  LEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIP-EEVPTGFPQNLHSEG 929

Query: 743  LNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTS 802
              +T+V L W PP L  +NGIIT Y ++   +++P    +      V   T++ +T L  
Sbjct: 930  TTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPL---LPMEQLIVPADTTMTLTGLKP 986

Query: 803  GVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETW-F 861
              +Y V++ A T  G GP+S  V F    R++ +D +  +  N  V  V    V+ +W  
Sbjct: 987  DTTYDVKVRAHTSKGPGPYSPSVQF----RTLPVDQV--FAKNFHVKAVMKTSVLLSWEI 1040

Query: 862  YFLIGAIVLFKIIVIAGIIYVRKYNIFAKKSALPNIYDSNGTSLVTQMNIKAAVSLSHPL 921
                 + + FKI+   G + V + +  A +  + N+      S V      +A  L H +
Sbjct: 1041 PENYNSAMPFKILYDDGKM-VEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSAGGLQHRV 1099

Query: 922  TS 923
            T+
Sbjct: 1100 TA 1101



 Score = 65.7 bits (153), Expect = 7e-09
 Identities = 55/198 (27%), Positives = 78/198 (39%), Gaps = 21/198 (10%)

Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
           PP    +P      SG VA F C ATG P P + W+ +G +      +S  ++      D
Sbjct: 23  PPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKK------VSNQRFEVIEFDD 76

Query: 352 GV-TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP--PIITNGPSNQT 408
           G  +VL I             C A N  G   V  +LTV  +D  P   P I  GP  + 
Sbjct: 77  GSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKV 136

Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFE--------GEALIQNHRRNVTND----GTLVLKD 456
           +     A   C A   P+P I W+ +            I+  R          G L ++ 
Sbjct: 137 VERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQ 196

Query: 457 LDKSDSGTYTCVASSRHG 474
            ++SD G Y CVA++  G
Sbjct: 197 SEESDQGKYECVATNSAG 214



 Score = 64.5 bits (150), Expect = 2e-08
 Identities = 52/210 (24%), Positives = 90/210 (42%), Gaps = 8/210 (3%)

Query: 642 TPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYT 701
           T   + +I L W+  N   +    I  +P ++  +  E+  +  +     + +  L  Y+
Sbjct: 332 TESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTR----YSVAGLSPYS 387

Query: 702 KYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQN 761
            YEF ++       G PS   + QT +  P   P +++  +L++TT+ ++W  PE    N
Sbjct: 388 DYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPE--EPN 445

Query: 762 GIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPF 821
           G I GY V           + +  N    Q T++   NL    +YSV++ A T IG GP 
Sbjct: 446 GQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTI--GNLVPQKTYSVKVLAFTSIGDGPL 503

Query: 822 SQKVYFNIDSRSVGLDLLSRYPMNGEVSIV 851
           S  +     +   G  L  +     E SI+
Sbjct: 504 SSDIQVITQTGVPGQPLNFKAEPESETSIL 533



 Score = 59.7 bits (138), Expect = 5e-07
 Identities = 42/171 (24%), Positives = 72/171 (42%), Gaps = 6/171 (3%)

Query: 690 SGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVH 749
           + + +  L+  + Y F L     +  G  +    A+T+   P  PP +I     ++T++ 
Sbjct: 568 TSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSIL 627

Query: 750 LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQ 809
           + W PP ++ QNGIIT Y++    +D   +K    +       T  ++  L     Y + 
Sbjct: 628 VSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIP-SDTTKYLLEQLEKWTEYRIT 686

Query: 810 IAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETW 860
           + A T +G GP S  V    +      D+ S  P   EV  V    V  +W
Sbjct: 687 VTAHTDVGPGPESLSVLIRTNE-----DVPSGPPRKVEVEAVNSTSVKVSW 732



 Score = 54.0 bits (124), Expect = 2e-05
 Identities = 27/83 (32%), Positives = 44/83 (53%)

Query: 687 NDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTT 746
           +D + + +  L K+T+Y   +        G  S S + +T +DVP GPP  +E+  +N+T
Sbjct: 667 SDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNST 726

Query: 747 TVHLKWSPPELQLQNGIITGYNV 769
           +V + W  P    Q+G I GY V
Sbjct: 727 SVKVSWRSPVPNKQHGQIRGYQV 749



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 33/98 (33%), Positives = 44/98 (44%), Gaps = 7/98 (7%)

Query: 393 DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT--NDG 450
           D   PP  T  P +QT     +A F C A   P P I W  +G+  + N R  V   +DG
Sbjct: 19  DAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKK-VSNQRFEVIEFDDG 77

Query: 451 T---LVLKDL-DKSDSGTYTCVASSRHGKYVWSGALLV 484
           +   L ++ L    D   Y CVAS+  G+   S  L V
Sbjct: 78  SGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTV 115


>UniRef50_UPI0000F2186B Cluster: PREDICTED: hypothetical protein; n=1;
            Danio rerio|Rep: PREDICTED: hypothetical protein - Danio
            rerio
          Length = 11202

 Score =  106 bits (255), Expect = 3e-21
 Identities = 130/517 (25%), Positives = 198/517 (38%), Gaps = 49/517 (9%)

Query: 6    VTSGEAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
            +T+   P   E  L D  VA  +   L C   G+P   + WYK G  + +    +    G
Sbjct: 597  ITTFTEPARFELKLKDKQVAMSKNLKLECTFTGAPKIFVTWYKDGKQLYASYRYNTTVVG 656

Query: 65   GLFFLRATHGRVHSDAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGD 123
                L   H       G Y CE +NSYG        T      R    L  +S Q  QG 
Sbjct: 657  NTCTLECLHECTKETPGKYSCEVSNSYGKDICHAEVTTFSGPARFVKTLTDQSLQ--QGQ 714

Query: 124  TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTD---AGRYQC 180
             + LE    +G  +  V W K+G+           ++ G   V++   + D    G+Y C
Sbjct: 715  KLRLEA-SFKGIGKIFVTWYKDGKQAYASYRCNTKVI-GNTCVLEYLHECDENTPGKYSC 772

Query: 181  IARNAAGTRE-SAIATL--KIHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
               N  G+    A+ TL  +  I P     P E +    G  V  + RV G     V+W 
Sbjct: 773  EVMNEDGSDICHALVTLGTERKIPPTFTKKPSEHIEDAEGKLVKLESRVSGSQPLSVIWY 832

Query: 237  RSAGGGN-MPLGRVKVLDDGSLR-LDNVILADEGEYSCEAENSVGAVSASGYLTVYD--- 291
            +     N   +  V    + ++  L    + D G Y+C A N  G  S    + + +   
Sbjct: 833  KDNKEINTSDIYDVSFKSNVAVMCLRKATVTDSGVYTCSASNEAGTASFQVVVNITEQKR 892

Query: 292  PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
            PP+ ++    + V  G     +C   G P   + W ++  R +     ++  +      D
Sbjct: 893  PPTFDIPLKPMTVSEGERLNLSCHVCGSPPVKIQW-MKDRREVTSSASTKMTF-----VD 946

Query: 352  GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN----- 406
            G   L IN   K D+    +C A N AGS F + K+T+       P      P+      
Sbjct: 947  GTATLEINQASKTDA-GDYLCKATNNAGSEFSKTKVTIKDKAGVAPAAAPAAPTTPQATK 1005

Query: 407  -----------QTLPI--KSMAVFPCTAICTPEPIIAWYFEGEALIQNH--RRNVTNDG- 450
                       +++ I  K  A F       P P + W  +G+     H  R N+   G 
Sbjct: 1006 KLDNLFFIEEPKSIHIVEKGTATFIAKVGGDPIPNVKW-MKGKWRQMTHGGRINIQQKGQ 1064

Query: 451  --TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485
               L +K++ KSDSG Y CVAS++HG+   S  L VD
Sbjct: 1065 ESKLEIKEVTKSDSGQYRCVASNKHGEIECSTDLNVD 1101



 Score = 93.5 bits (222), Expect = 3e-17
 Identities = 109/545 (20%), Positives = 201/545 (36%), Gaps = 29/545 (5%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
           +T+ E    + +  ++++   Q   L C+  G     + WYK G  + +    +      
Sbjct: 313 ITASEPARFLRKLSNISIPMSQKLRLECKFTGDRKLFVTWYKDGKQLYASYRYNTTVTDN 372

Query: 66  LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
              L +     ++  G+Y CE +N++G     +AT+        F  +           +
Sbjct: 373 SCTLESLQECDNTTTGIYSCEVSNAFG-REICHATVTAVTEPARFVKKLTDMSIPMSQKL 431

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV--IQDARQTDAGRYQCIAR 183
            LEC    G+P+  V W K+G+ L         +     ++  + +      GRY C   
Sbjct: 432 RLEC-TFTGAPKLFVTWYKDGKQLYASYRYNTKVTSNSCILECLHECNNETTGRYSCEVS 490

Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
           N  GT +     + +      +    DV       +  +C   G P   V W +   G  
Sbjct: 491 NIYGTDKCHAQVVAVTEPARFVKKLTDVAIPVTQKLRLECTFTGAPKIFVTWYKD--GKQ 548

Query: 244 MPLG---RVKVLDDGSLR--LDNVILADEGEYSCEAENSVGAVSASGYLTVY-DPPSINL 297
           +        KV+ D  +   L     A  G+YSCE  NS+G       +T + +P    L
Sbjct: 549 LYASYRYNTKVIGDTCILECLHECNDATPGKYSCEVSNSIGTDICHANITTFTEPARFEL 608

Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
                 V      +  CT TG P+  + W  +G +       +  +Y+ T V +  T+  
Sbjct: 609 KLKDKQVAMSKNLKLECTFTGAPKIFVTWYKDGKQL-----YASYRYNTTVVGNTCTLEC 663

Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
           +++  K ++     C   N  G      ++T  S   R    +T+    Q   ++  A F
Sbjct: 664 LHECTK-ETPGKYSCEVSNSYGKDICHAEVTTFSGPARFVKTLTDQSLQQGQKLRLEASF 722

Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLK---DLDKSDSGTYTCVASSRH 473
                   +  + WY +G+    ++R N    G T VL+   + D++  G Y+C   +  
Sbjct: 723 KGIG----KIFVTWYKDGKQAYASYRCNTKVIGNTCVLEYLHECDENTPGKYSCEVMNED 778

Query: 474 GKYVWSG--ALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK-I 530
           G  +      L  +  I P      +  +    G   K  +       +++ W ++NK I
Sbjct: 779 GSDICHALVTLGTERKIPPTFTKKPSEHIEDAEGKLVKLESRVSGSQPLSVIWYKDNKEI 838

Query: 531 GSSSI 535
            +S I
Sbjct: 839 NTSDI 843



 Score = 83.4 bits (197), Expect = 3e-14
 Identities = 113/565 (20%), Positives = 203/565 (35%), Gaps = 29/565 (5%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
           E    +++  D+++   Q   L C   G+P   + WYK G  + +    +         L
Sbjct: 412 EPARFVKKLTDMSIPMSQKLRLECTFTGAPKLFVTWYKDGKQLYASYRYNTKVTSNSCIL 471

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT--VVL 127
              H   +   G Y CE +N YGT +       V  + E  R   +    A   T  + L
Sbjct: 472 ECLHECNNETTGRYSCEVSNIYGTDKCH---AQVVAVTEPARFVKKLTDVAIPVTQKLRL 528

Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV--IQDARQTDAGRYQCIARNA 185
           EC    G+P+  V W K+G+ L         ++    ++  + +      G+Y C   N+
Sbjct: 529 EC-TFTGAPKIFVTWYKDGKQLYASYRYNTKVIGDTCILECLHECNDATPGKYSCEVSNS 587

Query: 186 AGTRESAIATLKIHIKPYLI-TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--G 242
            GT +   A +    +P       +D       ++  +C   G P   V W +       
Sbjct: 588 IGT-DICHANITTFTEPARFELKLKDKQVAMSKNLKLECTFTGAPKIFVTWYKDGKQLYA 646

Query: 243 NMPLGRVKVLDDGSLR-LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP-N 300
           +       V +  +L  L        G+YSCE  NS G       +T +  P+  +    
Sbjct: 647 SYRYNTTVVGNTCTLECLHECTKETPGKYSCEVSNSYGKDICHAEVTTFSGPARFVKTLT 706

Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHA-TAVFDGVTVLT-I 358
             +++ G   R   +  G  +  + W  +G +           Y   T V     VL  +
Sbjct: 707 DQSLQQGQKLRLEASFKGIGKIFVTWYKDGKQAYA-------SYRCNTKVIGNTCVLEYL 759

Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
           ++ D+N +     C  +N  GS      +T+   + + PP  T  PS      +   V  
Sbjct: 760 HECDEN-TPGKYSCEVMNEDGSDICHALVTL-GTERKIPPTFTKKPSEHIEDAEGKLVKL 817

Query: 419 CTAICTPEPI-IAWYFEGEALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRHG 474
            + +   +P+ + WY + + +  +   +V   +N   + L+    +DSG YTC AS+  G
Sbjct: 818 ESRVSGSQPLSVIWYKDNKEINTSDIYDVSFKSNVAVMCLRKATVTDSGVYTCSASNEAG 877

Query: 475 KYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSS 534
              +   + +     P         ++   G       H      V + W ++ +  +SS
Sbjct: 878 TASFQVVVNITEQKRPPTFDIPLKPMTVSEGERLNLSCHVCGSPPVKIQWMKDRREVTSS 937

Query: 535 ILGYQVEVFSRETLSGNNTPRNSRG 559
                  V    TL  N   +   G
Sbjct: 938 ASTKMTFVDGTATLEINQASKTDAG 962



 Score = 79.4 bits (187), Expect = 6e-13
 Identities = 105/489 (21%), Positives = 180/489 (36%), Gaps = 31/489 (6%)

Query: 2   SDDYVTSGEAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI 60
           S  +  S E P + ++ + ++      P    C    +P+   +W+K G  +       I
Sbjct: 213 SQGFTRSEEVPPVFKKKICNMESNIGNPVKFECEIEETPNVTFKWFKAGSEIKQSDKVRI 272

Query: 61  LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS- 119
           +       L         D+G Y C A+N +G + + +A L++        L   S  S 
Sbjct: 273 ISRQTTSSLELP-SPTKDDSGEYSCRASNKHG-SDTCSAQLNITASEPARFLRKLSNISI 330

Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV--IQDARQTDAGR 177
                + LEC    G  +  V W K+G+ L         + D    +  +Q+   T  G 
Sbjct: 331 PMSQKLRLEC-KFTGDRKLFVTWYKDGKQLYASYRYNTTVTDNSCTLESLQECDNTTTGI 389

Query: 178 YQCIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
           Y C   NA G RE   AT+    +P   +    D+       +  +C   G P   V W 
Sbjct: 390 YSCEVSNAFG-REICHATVTAVTEPARFVKKLTDMSIPMSQKLRLECTFTGAPKLFVTWY 448

Query: 237 RSAGGGNMPLG---RVKVLDDGSLR--LDNVILADEGEYSCEAENSVGAVSA-SGYLTVY 290
           +   G  +        KV  +  +   L        G YSCE  N  G     +  + V 
Sbjct: 449 KD--GKQLYASYRYNTKVTSNSCILECLHECNNETTGRYSCEVSNIYGTDKCHAQVVAVT 506

Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
           +P         V +      R  CT TG P+  + W  +G +       +  +Y+   + 
Sbjct: 507 EPARFVKKLTDVAIPVTQKLRLECTFTGAPKIFVTWYKDGKQL-----YASYRYNTKVIG 561

Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
           D   +  +++ + + +     C   N  G+      +T  ++   P          Q   
Sbjct: 562 DTCILECLHECN-DATPGKYSCEVSNSIGTDICHANITTFTE---PARFELKLKDKQVAM 617

Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTL-VLKDLDKSDSGTYT 466
            K++ +  CT    P+  + WY +G+ L  ++R N T   N  TL  L +  K   G Y+
Sbjct: 618 SKNLKL-ECTFTGAPKIFVTWYKDGKQLYASYRYNTTVVGNTCTLECLHECTKETPGKYS 676

Query: 467 CVASSRHGK 475
           C  S+ +GK
Sbjct: 677 CEVSNSYGK 685



 Score = 79.4 bits (187), Expect = 6e-13
 Identities = 114/474 (24%), Positives = 174/474 (36%), Gaps = 46/474 (9%)

Query: 10   EAPYI-IEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
            E P++   +PL DV V   + A   C      S  +RW+K G  +       I+ A GL 
Sbjct: 3733 EPPFVEFSKPLHDVEVKEKESAKFECEVSRE-SAKVRWFKDGAEIRKGKKYEII-AKGLQ 3790

Query: 68   FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
             +      V  D   Y C+A  S  +         + V+ EE R           +T  +
Sbjct: 3791 RILIISKAVFDDEAEYECDARTSKSSGM-------LTVVEEEARFTKNLANVEGTETDSI 3843

Query: 128  ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNA 185
            + +     P   V W K  Q +  +G    H+ DG    L+IQD R  DAG Y C    +
Sbjct: 3844 KMVCEVSKPSAEVTWHKGDQEIP-EGGRYEHVADGKKRILIIQDLRMDDAGEYHCKLPAS 3902

Query: 186  AGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
              T      TLKI  +    I  P++     G    F C V  D   +V W +  G   +
Sbjct: 3903 ETT-----GTLKISELAAEFIARPQNQETVEGEKAEFVCSVSKDNY-EVKWFK--GDKEL 3954

Query: 245  PL-GRVKVLDDGSLR---LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
                + +++ DG  R   + N  L DEG ++     ++G+V AS  L V +   I     
Sbjct: 3955 TTDDKYEIVVDGKRRALIIKNCELKDEGAFTA----NIGSVKASANLLVIEKLRIITPLK 4010

Query: 301  SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
               V+ G      C           W ++ N T     M        A  D V  L I  
Sbjct: 4011 DTQVKEGQEIVLNCEVNSEGAKAK-W-LKNNET-----MFESSKFVMAQRDTVFSLRIKA 4063

Query: 361  TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
             +K+D  +  + +  N  G    + K +           I     +  +  K    F C 
Sbjct: 4064 AEKSDEASYTI-TLTNQRGE---QAKCSANISVHEEALKIIEPLEDCEIEEKKTITFTC- 4118

Query: 421  AICTPEPIIAWYFEGEALIQNHR---RNVTNDGTLVLKDLDKSDSGTYTCVASS 471
             +  P   + W   G+ +  + R   R   +  TL +KD   +D G YT VA +
Sbjct: 4119 KVNRPNVTVQWMKAGQEITLSKRILYRVDKDKHTLTIKDCSLADEGEYTVVAGT 4172



 Score = 63.7 bits (148), Expect = 3e-08
 Identities = 107/456 (23%), Positives = 175/456 (38%), Gaps = 57/456 (12%)

Query: 370   IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK--SMAVFPCTAICTPEP 427
             I  +AVN +  S +   + V++++  PP I  +    + LP+K  S           P P
Sbjct: 10361 IAKTAVNISRPSEITDPILVSAENV-PPRIELSVQMKKMLPVKAGSDVCLEAEVFGKPMP 10419

Query: 428   IIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
              + W   GE L  +    ++    L    LD         V     G Y   G    ++ 
Sbjct: 10420 KVTWSKNGETLKADKEFKMSQKRHLFSLSLD--------AVTKLHAGNY---GIHAANAS 10468

Query: 488   INPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRET 547
              N          +  +PGPP       +    V LSW      G S I  Y V+   RET
Sbjct: 10469 GNTTAEI--QLKILDIPGPPASVKLDEILSDRVKLSWEAPLVDGGSPITNYVVD--KRET 10524

Query: 548   LSGNNTPRNSRGWVVIARRVHQ--THYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605
                         W  ++ ++ +  T   V+ LI G  Y F VR EN +G +G + +S+ V
Sbjct: 10525 SRAE--------WAQVSAKISRDTTECSVERLIEGHEYQFRVRAENHYG-TGDAIISEPV 10575

Query: 606   TVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLF 665
                  + + +   G  +      NI  +H+    +    D K+  L           G  
Sbjct: 10576 V----ARNPFTVPGACDPPVL-TNITKEHMTVSWKEPSDDGKSPIL-----------GYL 10619

Query: 666   IYFRPLDNIT-IEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN-SRV 723
             +  R    +   +   K +L        E+  L +  +YEF +I   K   GKPS+ S  
Sbjct: 10620 VEKRETKEVNWTKINRKPLLERT----LEVGGLSEGAQYEFRVIAVNKAGLGKPSDPSNA 10675

Query: 724   AQTLDDV-PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSM 782
             A  LD + P GPPI+ +      +T+ L W+ P     + I+ GY V    ++       
Sbjct: 10676 ASALDPLYPPGPPISPKAIDTTNSTIKLTWTKPANDGGSDIL-GYLVECKRIN---TTDW 10731

Query: 783   VAINTTVH-QATSLIMTNLTSGVSYSVQIAAETIIG 817
             +  N   + Q T+ ++T L     Y ++++A   IG
Sbjct: 10732 IRCNVPKNLQDTNYVVTGLLENSEYQLRVSAVNKIG 10767



 Score = 63.3 bits (147), Expect = 4e-08
 Identities = 83/324 (25%), Positives = 136/324 (41%), Gaps = 40/324 (12%)

Query: 504  PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRET---LSGNNTPRNSRGW 560
            PG PT+    ++T  +VTL+W + ++ G S I GY VE F  ET   +  N  P      
Sbjct: 5245 PGAPTRVQPSDITRDAVTLTWYEPDEDGGSPITGYWVERFDPETDKWIKSNKLP------ 5298

Query: 561  VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGV 620
                  +  T + VK L     Y F V  EN  G   PS  +D V + D  +  W     
Sbjct: 5299 ------IKDTTFRVKGLPTKKKYKFRVLAENLAGQGKPSVETDPVLIKDPIDPPW----- 5347

Query: 621  SNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNI-TIEYE 679
            +    +  +I      +L    P      K+   I+      G   + R  +++ T E+ 
Sbjct: 5348 APGKPFVKDIAKTS-ADLQWTRPEHDGGAKIESYIIEL-QKTGTEEWVRVAEDVPTTEHS 5405

Query: 680  MKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIE 739
            +K ++   + S F + ++    + E             PS+  V +    VP+ PP  +E
Sbjct: 5406 LKGLMEKQEYS-FRVKAINVAGESE----------PSDPSDPVVCKERLYVPN-PPRWLE 5453

Query: 740  MFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTN 799
            +  +      LKW+ P+       IT Y  VV   DV   ++  A++TTV + T   +T 
Sbjct: 5454 VVNITKINCDLKWTEPDSD-GGSPITNY--VVEKRDV-RRRTWQAVDTTV-KDTKYTVTP 5508

Query: 800  LTSGVSYSVQIAAETIIGLGPFSQ 823
            L+ G  Y  ++AAE  +G+  F +
Sbjct: 5509 LSEGSLYVFRVAAENAVGISEFCE 5532



 Score = 58.8 bits (136), Expect = 8e-07
 Identities = 75/327 (22%), Positives = 125/327 (38%), Gaps = 36/327 (11%)

Query: 298  SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV------FD 351
            S   +N  +G   +   T +G+P P + W  +G      P   +++ H   V       D
Sbjct: 7183 SQELLNCRAGTTLKIPATISGKPLPNVTWEFDGTA----PSEKKNERHTLPVDSDISSSD 7238

Query: 352  GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
              +V+TI ++  + S   I+ +A N AG+  V+ ++ V      P  I  +  +  T  +
Sbjct: 7239 TTSVVTIPESKLHHSGRYII-TANNQAGTKIVKVRVNVLDLPGAPKDITISDITRGTCRL 7297

Query: 412  KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG----TLVLKDLDKSDSGTYTC 467
                       C     I  YF  +  ++       N      +LV+ DL +     +  
Sbjct: 7298 SWKP-----PDCDGGDRIKSYFIEKKTVEGKAWTKVNPACTTQSLVVPDLIEGQEYLFRI 7352

Query: 468  VASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527
             A +R G            P    I   +A D    P PPT+    +V+   VTL+W   
Sbjct: 7353 RAENRFGY----------GPHTTTIEGTKARDPIHPPDPPTRVKIIDVSKGIVTLTWKPP 7402

Query: 528  NKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMFI 586
               G + +  Y +E    ++ SGN        W    RR +  T + V+ L  G  Y F 
Sbjct: 7403 KNDGGAPVTHYNIERLWWDS-SGN----QQESWRQCNRRDIDTTTFKVEDLHEGAEYEFR 7457

Query: 587  VRTENSHGLSGPSPVSDSVTVGDDSNS 613
            V+  N  G S PS  +  + V D + +
Sbjct: 7458 VKAVNEVGASRPSSTAGPIIVKDQNRA 7484



 Score = 57.2 bits (132), Expect = 3e-06
 Identities = 81/305 (26%), Positives = 129/305 (42%), Gaps = 36/305 (11%)

Query: 304  VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
            V++G+         G P PT  W  EGN        +  K+      +  T LTI++  +
Sbjct: 8666 VKAGSTILLPAVMLGIPTPTAKWQSEGNEL-----KTEGKFKIVTEGNSTT-LTISECAR 8719

Query: 364  NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN--QTLPIKSMAVFPCTA 421
             DS    + +  N AGS  V   L VT  D    P+   GP N  +  P   +  +    
Sbjct: 8720 TDSGEYSL-TVSNPAGSKSVA--LHVTVLDVPSAPV---GPVNILEVTPDHMIIQWRAPK 8773

Query: 422  ICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLK-DLDKSDSGTYTCVASSRHGKYVWS 479
                 P++++  E + + +     +V + G+   K  + + + G    V      K +  
Sbjct: 8774 DDGGSPLMSYVVEKKDVKKPWEPWSVVSSGSTSTKAKVPRLEKGREYIVRVRAENK-IGI 8832

Query: 480  GALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQ 539
            GA L +SP  P I    A  +   PGPP +P   ++T+ +VT+SW++    G S + GY 
Sbjct: 8833 GAGL-ESP--PTI----AKQMFDPPGPPGQPTCSDITENAVTVSWAEPETDGGSPVSGYI 8885

Query: 540  VEVFSRETLSGNNTPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
            VE   R  ++G         W+ + +  V    Y V  L  G +Y F +  EN  G+S P
Sbjct: 8886 VE---RREMTGK--------WIRVNKTPVLDIRYRVCGLFEGNSYEFRIFAENVAGVSQP 8934

Query: 599  SPVSD 603
            S  SD
Sbjct: 8935 SYPSD 8939



 Score = 56.8 bits (131), Expect = 3e-06
 Identities = 72/276 (26%), Positives = 113/276 (40%), Gaps = 46/276 (16%)

Query: 503  LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
            +P PP      N+T  +  L W++ +  G S I  Y VE   R+           R W  
Sbjct: 5445 VPNPPRWLEVVNITKINCDLKWTEPDSDGGSPITNYVVE--KRDV--------RRRTWQA 5494

Query: 563  IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSN 622
            +   V  T Y V  L  G  Y+F V  EN+ G+S    + DSV   D        T  + 
Sbjct: 5495 VDTTVKDTKYTVTPLSEGSLYVFRVAAENAVGISEFCELEDSVLAKD--------TFTTP 5546

Query: 623  STEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKT 682
               Y    LT  +VE      +  + + L WE  N    +G     RP+    IE + K 
Sbjct: 5547 GPPY---ALT--VVE------VSKRHVDLKWEPPN---SDG----GRPITKYVIEKKEKV 5588

Query: 683  ---ILHSNDVSG----FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDV--PDG 733
                + S   SG    + +T + + T+ +F +    +   G PS   V  T++D   P  
Sbjct: 5589 GTRWVKSGKTSGPESKYRVTDVDEGTEVQFQVRAENEAGVGHPSEPTVIMTIEDAISPPS 5648

Query: 734  PPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNV 769
            PP+ +++   +   +++ W  PE +     ITGY+V
Sbjct: 5649 PPLEVKIVDASREHINITWKAPE-KNGGSPITGYHV 5683



 Score = 55.6 bits (128), Expect = 8e-06
 Identities = 51/179 (28%), Positives = 75/179 (41%), Gaps = 32/179 (17%)

Query: 425   PEPIIAWYFEGEALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
             P P   W      ++ + R  V    N   L++KD+ + DSG Y+ VA +  GK   +  
Sbjct: 10020 PAPACQWKRGENNVVSSSRLAVHKSQNMCVLIIKDVSRQDSGEYSLVAENSSGKIEQTLK 10079

Query: 482   LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSV-TLSWSQNNKIGSSSILGYQV 540
             +++                  +PGPP  P   +  D+   TLSW++  + G S+I  Y V
Sbjct: 10080 III----------------RDIPGPPEPPFEISDIDSDACTLSWNKPTEDGGSNITNYVV 10123

Query: 541   EVFSRETLSGNNTPRNSRG-WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
             E               SRG WV       +    +  LIPG  Y+F VR EN  G+S P
Sbjct: 10124 EKCD-----------VSRGDWVTALSSCGKAGCRIGKLIPGKEYIFRVRAENRFGISDP 10171



 Score = 53.6 bits (123), Expect = 3e-05
 Identities = 126/538 (23%), Positives = 183/538 (34%), Gaps = 62/538 (11%)

Query: 14   IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
            II    D  V   Q   LNC      + A +W K    +   +   +     +F LR   
Sbjct: 4005 IITPLKDTQVKEGQEIVLNCEVNSEGAKA-KWLKNNETMFESSKFVMAQRDTVFSLRIKA 4063

Query: 74   GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL-EP-ESKQSAQGDTVVLECLP 131
                SD   Y    TN  G     +A  +++V  E  ++ EP E  +  +  T+   C  
Sbjct: 4064 AE-KSDEASYTITLTNQRGEQAKCSA--NISVHEEALKIIEPLEDCEIEEKKTITFTCKV 4120

Query: 132  PRGSPEPNVYWKKNGQTLLFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
             R  P   V W K GQ +         +  D   L I+D    D G Y  +A     T E
Sbjct: 4121 NR--PNVTVQWMKAGQEITLSKRILYRVDKDKHTLTIKDCSLADEGEYTVVAGTDKATAE 4178

Query: 191  SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RV 249
              I+         L     D          F C++  +    V W R+  G  +  G R 
Sbjct: 4179 LIISEAPADFAAQL----RDQTITEFEDAEFTCKLSKEK-AHVKWYRN--GREIREGPRY 4231

Query: 250  KVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
             +  DG    L +      DE EY+C  E+     S +       P  I   P  V    
Sbjct: 4232 HLERDGKECKLVVKECRPDDECEYACGVEDK---RSRARLFVEEIPVEIVRPPTDVFEPP 4288

Query: 307  GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH--ATAVFDGVTVLTINDTDKN 364
            G+   F      +    + W    N  II  G   DKY   +      + V  I   D+ 
Sbjct: 4289 GSDIVFE-AELNKDRVEVKWM--RNNMIIVQG---DKYQMISEGKVHRLQVCEIRPRDQG 4342

Query: 365  DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
            + R  IV      A     R KL + +      P I     N         V        
Sbjct: 4343 EYR--IV------AKEKDARAKLELAA-----IPKIKTTDQNLVTDAGKPFVMAVPYDAY 4389

Query: 425  PEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
            P     W+F+ +  +     + +N+ T   LK+  KSD G Y  V  ++HG    +G   
Sbjct: 4390 PRAEAEWFFD-DISLPGQNIDTSNERTEYRLKEPKKSDQGRYKIVIKNKHG----TGEAF 4444

Query: 484  VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541
            ++             DV  +PGP       +  D  V+L+W +    G S IL Y VE
Sbjct: 4445 IN------------LDVIDVPGPVKNLHVVDTADGEVSLAWEEPESDGGSKILAYVVE 4490



 Score = 52.0 bits (119), Expect = 1e-04
 Identities = 62/230 (26%), Positives = 94/230 (40%), Gaps = 22/230 (9%)

Query: 374  AVNYAGSSFVRGKLT-VTSDDDRPPPIITNGPSNQTL---PIKSMAVFPCTAICTPEPII 429
            AVN AG S    + + +   D    P+IT   ++Q L      +    P T    P P +
Sbjct: 7150 AVNAAGESEPSPRTSDIIVQDILEEPVITIDVTSQELLNCRAGTTLKIPATISGKPLPNV 7209

Query: 430  AWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPIN 489
             W F+G A   + ++N  +  TL + D D S S T T V +    K   SG  ++ +   
Sbjct: 7210 TWEFDGTA--PSEKKNERH--TLPV-DSDISSSDT-TSVVTIPESKLHHSGRYIITANNQ 7263

Query: 490  PNIHFFRA-ADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETL 548
                  +   +V  LPG P      ++T  +  LSW   +  G   I  Y +E   ++T+
Sbjct: 7264 AGTKIVKVRVNVLDLPGAPKDITISDITRGTCRLSWKPPDCDGGDRIKSYFIE---KKTV 7320

Query: 549  SGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
             G       + W  +         VV  LI G  Y+F +R EN  G  GP
Sbjct: 7321 EG-------KAWTKVNPACTTQSLVVPDLIEGQEYLFRIRAENRFGY-GP 7362



 Score = 51.2 bits (117), Expect = 2e-04
 Identities = 49/211 (23%), Positives = 86/211 (40%), Gaps = 17/211 (8%)

Query: 273 EAENSVGAVSASGYLTVYDPPSINLSPNSVNVES--GNVARFTCTATGRPEPTMFWSVEG 330
           E ++++   ++ G+    + P +       N+ES  GN  +F C     P  T  W   G
Sbjct: 203 EEKHTLTGETSQGFTRSEEVPPV-FKKKICNMESNIGNPVKFECEIEETPNVTFKWFKAG 261

Query: 331 NRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT 390
           +          DK    +     + L +    K+DS     C A N  GS     +L +T
Sbjct: 262 SEI-----KQSDKVRIIS-RQTTSSLELPSPTKDDS-GEYSCRASNKHGSDTCSAQLNIT 314

Query: 391 SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT--- 447
           + +   P       SN ++P+       C      +  + WY +G+ L  ++R N T   
Sbjct: 315 ASE---PARFLRKLSNISIPMSQKLRLECKFTGDRKLFVTWYKDGKQLYASYRYNTTVTD 371

Query: 448 NDGTL-VLKDLDKSDSGTYTCVASSRHGKYV 477
           N  TL  L++ D + +G Y+C  S+  G+ +
Sbjct: 372 NSCTLESLQECDNTTTGIYSCEVSNAFGREI 402



 Score = 50.4 bits (115), Expect = 3e-04
 Identities = 59/231 (25%), Positives = 94/231 (40%), Gaps = 31/231 (13%)

Query: 6    VTSGEAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
            +T  + P   + PL  +TV+  +   L+C   GSP   I+W K    V S     +    
Sbjct: 887  ITEQKRPPTFDIPLKPMTVSEGERLNLSCHVCGSPPVKIQWMKDRREVTSSASTKMTFVD 946

Query: 65   GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNA------------------TLHVAVL 106
            G   L        +DAG Y C+ATN+ G+  S+                    T   A  
Sbjct: 947  GTATLEINQAS-KTDAGDYLCKATNNAGSEFSKTKVTIKDKAGVAPAAAPAAPTTPQATK 1005

Query: 107  REE---FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG 163
            + +   F  EP+S    +  T         G P PNV W K     +  G  R+++   G
Sbjct: 1006 KLDNLFFIEEPKSIHIVEKGTATF-IAKVGGDPIPNVKWMKGKWRQMTHG-GRINIQQKG 1063

Query: 164  N---LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDV 211
                L I++  ++D+G+Y+C+A N  G  E    +  +++     +GPE V
Sbjct: 1064 QESKLEIKEVTKSDSGQYRCVASNKHGEIE---CSTDLNVDEKKESGPEVV 1111



 Score = 50.4 bits (115), Expect = 3e-04
 Identities = 35/114 (30%), Positives = 50/114 (43%), Gaps = 4/114 (3%)

Query: 499  DVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558
            D   LPGPP +P   + T +S+ ++W      G S+I GY +E   R  +  +   R   
Sbjct: 6961 DPFGLPGPPQRPRIISHTRSSMVVTWEPPKDNGGSTIQGYWLEKRERGAVYWSRVNRAP- 7019

Query: 559  GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSN 612
               V    V    Y V  LI G  Y F V  +N+ G+  PS  ++ V   D  N
Sbjct: 7020 ---VTKPAVKGLEYNVLHLIEGAEYKFRVMAQNAAGVGPPSEATECVFALDPRN 7070



 Score = 48.8 bits (111), Expect = 9e-04
 Identities = 45/185 (24%), Positives = 72/185 (38%), Gaps = 29/185 (15%)

Query: 418  PCTAICTPEPIIAWYFEGEALIQNHRRNV-TNDG--TLVLKDLDKSDSGTYTCVASSRHG 474
            P   +  PEP + W      L    R  + T  G  TL + +  +SD+ TY   A +  G
Sbjct: 5073 PADVLGKPEPRVKWTKADLVLKPEERITIDTKPGHSTLSIANTTRSDTATYIIEAVNTSG 5132

Query: 475  KYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSS 534
            +        VD             ++   PGPP       +T+ S  L+W+     G S 
Sbjct: 5133 R----ATATVD------------VNILDKPGPPAAFDISEITNESCCLAWNAPRDDGGSP 5176

Query: 535  ILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHG 594
            +  Y VE+           P +   W  ++  + QT +    L+P   Y+F V  EN +G
Sbjct: 5177 VANYIVEM----------RPTDKEEWQKLSATIKQTAFKATKLVPLKEYVFRVSAENQYG 5226

Query: 595  LSGPS 599
            +  P+
Sbjct: 5227 IGTPA 5231



 Score = 48.0 bits (109), Expect = 0.002
 Identities = 35/104 (33%), Positives = 50/104 (48%), Gaps = 4/104 (3%)

Query: 121   QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRY 178
             +G  V L+ +P  G P P V WKK     L D           N  L+I+D ++TDA +Y
Sbjct: 11092 EGSNVRLK-IPIIGKPTPAVSWKKGEDENLTDTGRVCVESTAVNTTLLIRDCQRTDASKY 11150

Query: 179   QCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQ 222
                 RN+AGT+ES I  +++  KP +  GP      T    T +
Sbjct: 11151 TITLRNSAGTKESTI-FVRVVGKPGIPNGPIKFKEVTADGATLK 11193



 Score = 47.6 bits (108), Expect = 0.002
 Identities = 28/97 (28%), Positives = 47/97 (48%), Gaps = 4/97 (4%)

Query: 209  EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILA 265
            E +V + GS++     + G P P   W+ S G      G+ K++ +G+   L +      
Sbjct: 8662 EGLVVKAGSTILLPAVMLGIPTPTAKWQ-SEGNELKTEGKFKIVTEGNSTTLTISECART 8720

Query: 266  DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
            D GEYS    N  G+ S + ++TV D PS  + P ++
Sbjct: 8721 DSGEYSLTVSNPAGSKSVALHVTVLDVPSAPVGPVNI 8757



 Score = 47.2 bits (107), Expect = 0.003
 Identities = 30/102 (29%), Positives = 46/102 (45%), Gaps = 12/102 (11%)

Query: 504   PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV-- 561
             PGPP  P   + T++++ L+W++    G S ILGY VE              N+  W+  
Sbjct: 10685 PGPPISPKAIDTTNSTIKLTWTKPANDGGSDILGYLVEC----------KRINTTDWIRC 10734

Query: 562   VIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
              + + +  T+YVV  L+    Y   V   N  G S P  V +
Sbjct: 10735 NVPKNLQDTNYVVTGLLENSEYQLRVSAVNKIGFSQPCEVPE 10776



 Score = 46.8 bits (106), Expect = 0.004
 Identities = 37/132 (28%), Positives = 56/132 (42%), Gaps = 13/132 (9%)

Query: 484  VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543
            V  P  P +      D  S P PP +    + +   + ++W    K G S I GY VE+ 
Sbjct: 5628 VGHPSEPTV-IMTIEDAISPPSPPLEVKIVDASREHINITWKAPEKNGGSPITGYHVELS 5686

Query: 544  SRETLSGNNTPRNSRGWVVI-ARRVHQTHY-VVKSLIPGITYMFIVRTENSHGLSGPSPV 601
              ET            W+ I  R V +  +   + +IP   Y+  VR  N+ G+S PS +
Sbjct: 5687 EAET----------EKWMRINPRPVKELRFKAEEGIIPEKKYVLRVRAINAIGVSDPSEI 5736

Query: 602  SDSVTVGDDSNS 613
            SD V   D  ++
Sbjct: 5737 SDGVFAKDPDSA 5748



 Score = 46.0 bits (104), Expect = 0.006
 Identities = 37/112 (33%), Positives = 48/112 (42%), Gaps = 12/112 (10%)

Query: 491  NIHFFRAA--DVSSL--PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRE 546
            N H F  A  DV+ L  PGPP       + +TSV  +W      G S I+ Y +E     
Sbjct: 6152 NAHGFATASCDVNVLDKPGPPVNFGFDEIRNTSVVCTWDAPLDDGGSEIINYILE----- 6206

Query: 547  TLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
                +NT  +  GWV +       +Y V  LI G  Y+F V  EN  G   P
Sbjct: 6207 --KKDNTS-DDIGWVTVTSTHKGYNYPVTKLIEGKEYIFRVTAENKFGCGHP 6255



 Score = 46.0 bits (104), Expect = 0.006
 Identities = 33/116 (28%), Positives = 52/116 (44%), Gaps = 11/116 (9%)

Query: 122  GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRY 178
            G T++L  +   G P P   W+  G  L  +G  +  +V  GN   L I +  +TD+G Y
Sbjct: 8669 GSTILLPAVM-LGIPTPTAKWQSEGNELKTEG--KFKIVTEGNSTTLTISECARTDSGEY 8725

Query: 179  QCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV----GGDPL 230
                 N AG++  A+    + + P    GP +++  T   +  Q R     GG PL
Sbjct: 8726 SLTVSNPAGSKSVALHVTVLDV-PSAPVGPVNILEVTPDHMIIQWRAPKDDGGSPL 8780



 Score = 45.6 bits (103), Expect = 0.008
 Identities = 74/330 (22%), Positives = 128/330 (38%), Gaps = 37/330 (11%)

Query: 496  RAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPR 555
            +A D+  +P  P +P   +V + S  + W++    G   I  Y +E   ++  S     R
Sbjct: 8242 KAKDLFRVPEAPEQPTVKDVYNDSALVIWNRPRD-GGKPITNYILE---KKEPSAKRWSR 8297

Query: 556  NSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLW 615
             +R  +  A     T Y V+ L+ G  Y F V  EN  G   PS  S  +   D      
Sbjct: 8298 ATRDPIYPA-----TQYRVQELVEGCEYEFRVTAENEIGTGDPSVPSKPILAKDP----- 8347

Query: 616  EGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNI- 674
                          I+      L EA      ++ L W +        +F Y        
Sbjct: 8348 --------------IVLPSPPVLPEAVDKTKDSVSLSWRVPRHDGKGKIFGYLIEYQKPG 8393

Query: 675  TIEY-EMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPD- 732
             IE+ +      S   + F +T+L +  +++F ++      + +P+  +    + D  D 
Sbjct: 8394 AIEWVKANETPESCPDTKFVVTNLPEGEEFQFRIMAVNAAGKSEPAYVKEPVKVHDRLDK 8453

Query: 733  -GPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQ 791
             GPP N+ +  + + + +L W  PE      +I+ Y  +V   DV A ++ V +     +
Sbjct: 8454 PGPPRNLAISEITSESAYLTWQKPE-DDGGAVISHY--IVQKKDVAA-ENWVPV-CAASK 8508

Query: 792  ATSLIMTNLTSGVSYSVQIAAETIIGLGPF 821
              SL+   L  G  Y  ++AAE   G   F
Sbjct: 8509 KLSLMAQYLMEGTQYLFRVAAENQFGRSAF 8538



 Score = 45.6 bits (103), Expect = 0.008
 Identities = 30/105 (28%), Positives = 49/105 (46%), Gaps = 7/105 (6%)

Query: 507   PTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARR 566
             P KP   +VT  +V+L W++    G S I+GY VE      L G+   R +      ++ 
Sbjct: 10287 PGKPEVLDVTKNAVSLVWTKPKNDGGSKIIGYYVEAM---RLPGDTWVRCNTS----SQN 10339

Query: 567   VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDS 611
             V +  Y    L  G  Y F V  + +  +S PS ++D + V  ++
Sbjct: 10340 VPREEYTATGLEEGANYQFRVIAKTAVNISRPSEITDPILVSAEN 10384



 Score = 44.8 bits (101), Expect = 0.015
 Identities = 38/153 (24%), Positives = 64/153 (41%), Gaps = 18/153 (11%)

Query: 460   SDSGTYTCVAS-SRH--GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVT 516
             +D+ T  CV   +R+  GKY+    L +DS     ++      V   PGPP   +    +
Sbjct: 10841 TDTDTLVCVEKVNRYDAGKYI----LNLDSVSGMKMYTV-IVKVLDTPGPPLNLMIKETS 10895

Query: 517   DTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKS 576
               S ++ W +    G S I GY V+    E           + W  +     +T + ++ 
Sbjct: 10896 KDSASILWDEPLIDGGSEITGYIVDKRDAER----------KAWSNVTTSCTKTSFKIED 10945

Query: 577   LIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
             L PG +Y F V  +N +G+  P    D+V   +
Sbjct: 10946 LEPGRSYCFRVLAQNQYGIGEPCETVDAVRASE 10978



 Score = 44.4 bits (100), Expect = 0.019
 Identities = 78/335 (23%), Positives = 127/335 (37%), Gaps = 38/335 (11%)

Query: 497  AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGN--NTP 554
            A D  + P  P  P+  + + +SV+LSW+  ++ G S I GY VEV    +      NTP
Sbjct: 7065 ALDPRNPPSQPPAPVVTDKSPSSVSLSWTPPDRDGGSPIKGYIVEVQDEGSHEWKRINTP 7124

Query: 555  RNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSL 614
                      + +    Y V  L       F +   N+ G S PSP +  + V D     
Sbjct: 7125 ---------DKLILTNSYTVPGLKENKKCRFRIVAVNAAGESEPSPRTSDIIVQDILEEP 7175

Query: 615  WEGTGVSNSTEYRN--NILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLD 672
                 V+ S E  N     T  I   I   P+ + T    WE          F    P +
Sbjct: 7176 VITIDVT-SQELLNCRAGTTLKIPATISGKPLPNVT----WE----------FDGTAPSE 7220

Query: 673  NITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPD 732
                + E  T+   +D+S  + TS+    + +      Y       + +++ +   +V D
Sbjct: 7221 K---KNERHTLPVDSDISSSDTTSVVTIPESKLHHSGRYIITANNQAGTKIVKVRVNVLD 7277

Query: 733  --GPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH 790
              G P +I +  +   T  L W PP+       I  Y +    ++    K+   +N    
Sbjct: 7278 LPGAPKDITISDITRGTCRLSWKPPDCD-GGDRIKSYFIEKKTVE---GKAWTKVNPAC- 7332

Query: 791  QATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
               SL++ +L  G  Y  +I AE   G GP +  +
Sbjct: 7333 TTQSLVVPDLIEGQEYLFRIRAENRFGYGPHTTTI 7367



 Score = 44.0 bits (99), Expect = 0.025
 Identities = 37/127 (29%), Positives = 55/127 (43%), Gaps = 13/127 (10%)

Query: 484  VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543
            V  P  P+   F    ++  P PPT  +T + T T+  L W    K G S I+GY VE +
Sbjct: 7641 VGPPSEPSEPTFAREPIAP-PSPPTPKVT-DWTKTTADLEWIPPLKDGGSKIIGYFVE-Y 7697

Query: 544  SRETLSGNNTPRNSRGWVVIA-RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602
              E          +  WV    + V  T +V+  L     + F V   N+ GL  P  V+
Sbjct: 7698 KEE---------GTEAWVKAKDKEVRGTKFVITGLKENALFKFRVIALNAAGLGEPGEVA 7748

Query: 603  DSVTVGD 609
            D++ + D
Sbjct: 7749 DALEMKD 7755



 Score = 43.6 bits (98), Expect = 0.034
 Identities = 30/84 (35%), Positives = 42/84 (50%), Gaps = 5/84 (5%)

Query: 122  GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRY 178
            GD V +E     G P+P V W K G T       R+ +  G N   L + ++R+ D G+Y
Sbjct: 9361 GDAVSIEA-ELLGKPQPEVKWSKEGDTRDISKGLRVQVETGTNFTKLQLSNSRRGDTGKY 9419

Query: 179  QCIARNAAGTRESAIATLKIHIKP 202
               A NAAGT  SA A + +  +P
Sbjct: 9420 IITATNAAGTC-SAEAKVNVLDRP 9442



 Score = 43.6 bits (98), Expect = 0.034
 Identities = 38/136 (27%), Positives = 54/136 (39%), Gaps = 15/136 (11%)

Query: 474  GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSS 533
            GKY    +L V SP      F     V   PGP       ++T +S  L+WS     G S
Sbjct: 9728 GKY----SLNVSSPAGEKAVFVNVK-VLDTPGPVDGLEVTDMTMSSCNLTWSPPETDGGS 9782

Query: 534  SILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSH 593
            ++  Y VE   RE         + + W  +   V +T + + +L+PG  Y F V   N +
Sbjct: 9783 NVTHYIVE--KREI--------DRKTWATVKANVEKTTFKISNLVPGTEYYFRVVAVNEY 9832

Query: 594  GLSGPSPVSDSVTVGD 609
            G   P     S    D
Sbjct: 9833 GPGVPRVTPKSYLASD 9848



 Score = 43.2 bits (97), Expect = 0.044
 Identities = 66/294 (22%), Positives = 126/294 (42%), Gaps = 36/294 (12%)

Query: 495  FRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTP 554
            F A D    PGP +     + + TS+TL+W++    G + ++GY VE+  + T       
Sbjct: 9633 FTARDPVEPPGPVSNLKVTDSSKTSITLAWTKPTYDGGAPLIGYVVEIRVKGT-----GK 9687

Query: 555  RNSRGW--VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSN 612
            +   GW    +A ++  T + V SL   + Y F V  ++    SG   ++ S   G+   
Sbjct: 9688 KGDEGWKRCNVAAQLIGTEFTVSSLDEKLEYEFRVTRDD----SGKYSLNVSSPAGE--K 9741

Query: 613  SLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMW---EILNFYYLEGLFIYFR 669
            +++    V +         T   V+ +E T +   +  L W   E      +    +  R
Sbjct: 9742 AVFVNVKVLD---------TPGPVDGLEVTDMTMSSCNLTWSPPETDGGSNVTHYIVEKR 9792

Query: 670  PLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKP---SNSRVAQT 726
             +D  T      T+  + + + F+I++L   T+Y F ++   +   G P     S +A  
Sbjct: 9793 EIDRKT----WATVKANVEKTTFKISNLVPGTEYYFRVVAVNEYGPGVPRVTPKSYLASD 9848

Query: 727  LDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANK 780
                PD PP  +++  ++  +  + W  P ++     I GY  V+++L++P  K
Sbjct: 9849 PVSKPD-PPQKVDVLEISKNSATVGWVKP-MRDGGAKIDGY--VIDYLELPMPK 9898



 Score = 42.7 bits (96), Expect = 0.059
 Identities = 34/137 (24%), Positives = 55/137 (40%), Gaps = 6/137 (4%)

Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LV 453
           PP+      N    I +   F C    TP     W+  G  + Q+ +  + +  T   L 
Sbjct: 223 PPVFKKKICNMESNIGNPVKFECEIEETPNVTFKWFKAGSEIKQSDKVRIISRQTTSSLE 282

Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITH 513
           L    K DSG Y+C AS++HG    S  L + +  +    F R     S+P      +  
Sbjct: 283 LPSPTKDDSGEYSCRASNKHGSDTCSAQLNITA--SEPARFLRKLSNISIPMSQKLRLEC 340

Query: 514 NVT-DTSVTLSWSQNNK 529
             T D  + ++W ++ K
Sbjct: 341 KFTGDRKLFVTWYKDGK 357



 Score = 42.3 bits (95), Expect = 0.078
 Identities = 37/141 (26%), Positives = 60/141 (42%), Gaps = 6/141 (4%)

Query: 159   LVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL----ITGPEDVVAQ 214
             +V G ++ I   ++    R++  ARN+ G+           IK  +    I   E V A+
Sbjct: 9946  VVKGLSISIAGLKEGRKYRFRVAARNSMGSSLPTETREAYEIKEQMFEPKIIMTELVTAK 10005

Query: 215   TGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSC 272
              G+ +  +  V G P P   W+R       +  L   K  +   L + +V   D GEYS 
Sbjct: 10006 AGAKLRVEALVSGKPAPACQWKRGENNVVSSSRLAVHKSQNMCVLIIKDVSRQDSGEYSL 10065

Query: 273   EAENSVGAVSASGYLTVYDPP 293
              AENS G +  +  + + D P
Sbjct: 10066 VAENSSGKIEQTLKIIIRDIP 10086



 Score = 41.9 bits (94), Expect = 0.10
 Identities = 33/104 (31%), Positives = 47/104 (45%), Gaps = 13/104 (12%)

Query: 496  RAADVSSLPGPPTKPITHNVTD-TSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTP 554
            +A D    PGPP K + H   D T V L W   ++ G S I G+ VE          +  
Sbjct: 8546 KAVDPLYPPGPP-KNLHHVDADKTEVWLQWEWPDRTGGSEITGFIVE----------HQE 8594

Query: 555  RNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
              +  WV   + V      V  L+ G TY F V+++N+ G+S P
Sbjct: 8595 EGATDWVTF-KTVSNPQCHVTGLVEGKTYRFRVKSQNAIGISRP 8637



 Score = 41.5 bits (93), Expect = 0.14
 Identities = 32/100 (32%), Positives = 47/100 (47%), Gaps = 5/100 (5%)

Query: 504  PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
            PG   KP   +VT  S+T++W +    G S I GY +E   R+  +     R +R   V 
Sbjct: 7555 PGQCEKPTISSVTIDSMTVNWEEPESDGGSPITGYWLE---RKETTSKRWSRVTRD-PVR 7610

Query: 564  ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
               +  +H V   LI G  Y+F V   N+ G+  PS  S+
Sbjct: 7611 PMPMGVSHRVT-GLIEGSQYLFRVSAINAAGVGPPSEPSE 7649



 Score = 41.1 bits (92), Expect = 0.18
 Identities = 31/106 (29%), Positives = 42/106 (39%), Gaps = 9/106 (8%)

Query: 504  PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
            P PP +    N T  S+T++W      G   I GY +E   ++   G+   R       +
Sbjct: 5942 PDPPIEVAGLNPTSNSITVTWMAPPYDGGCPITGYIIEKIEKD---GDRFER------CV 5992

Query: 564  ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
               V    Y V  L  G  Y F VR EN  G S PS  +  +   D
Sbjct: 5993 PNLVPGFSYTVTGLTEGKEYQFRVRAENIAGASDPSRSTPLIMAAD 6038



 Score = 41.1 bits (92), Expect = 0.18
 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 4/87 (4%)

Query: 211  VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS----LRLDNVILAD 266
            +V + G +V+ +  + G P P+V W +     ++  G    ++ G+    L+L N    D
Sbjct: 9356 LVVKAGDAVSIEAELLGKPQPEVKWSKEGDTRDISKGLRVQVETGTNFTKLQLSNSRRGD 9415

Query: 267  EGEYSCEAENSVGAVSASGYLTVYDPP 293
             G+Y   A N+ G  SA   + V D P
Sbjct: 9416 TGKYIITATNAAGTCSAEAKVNVLDRP 9442



 Score = 40.7 bits (91), Expect = 0.24
 Identities = 38/163 (23%), Positives = 71/163 (43%), Gaps = 15/163 (9%)

Query: 122  GDTVVLECLPPRGSPEPNVY-WKKNGQTLLFDGDSRMHLVDGGNLVIQ--DARQTDAGRY 178
            G + V EC   + SP   +  W K+G  +  +        DG +  +Q  D + +D G Y
Sbjct: 2676 GSSAVFEC---QISPSTAITTWMKDGSNIR-ESPKHKFTSDGKDRKLQIIDVQLSDTGEY 2731

Query: 179  QCIARNAAGTRESAIATLKIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
             C+A+      +++ A L +   P   T    E+     G  +   C +  D   DV+W+
Sbjct: 2732 TCVAK-LGNKEKTSTAKLVVEELPVKFTKNLEEETSVLKGQPMYLTCELSKD--KDVVWK 2788

Query: 237  RSAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAEN 276
            ++        G++++   G   ++ + ++   D G Y+CE EN
Sbjct: 2789 KNGKELKEIPGKIQINIIGLQRAVTIQDMNDDDAGVYTCECEN 2831



 Score = 40.3 bits (90), Expect = 0.31
 Identities = 35/100 (35%), Positives = 48/100 (48%), Gaps = 15/100 (15%)

Query: 504  PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV-V 562
            P  P  P    VT ++V LSW +    GS  ILGY VE   RE         NS+ W+ V
Sbjct: 6270 PDAPNVPRIGEVTSSTVALSWHEPKDNGSP-ILGYWVE--RREV--------NSKYWIRV 6318

Query: 563  IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602
             +  +   +  V+ L+ G+ Y+F V  EN   L+GP   S
Sbjct: 6319 NSNLLSALNVKVEGLMEGLVYVFRVCAEN---LAGPGEFS 6355



 Score = 39.9 bits (89), Expect = 0.41
 Identities = 23/65 (35%), Positives = 38/65 (58%), Gaps = 7/65 (10%)

Query: 133  RGSPEPNVYWKKNGQTLLFDGDSRMH----LVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
            +G P+P + W K+ + L  D  + M+    LV+   LVIQDA + D G+Y   A+N++G 
Sbjct: 9078 KGRPDPEITWTKDARVLGRDKRTEMNNNFPLVE---LVIQDAVRADYGKYAIQAKNSSGQ 9134

Query: 189  RESAI 193
             ++ I
Sbjct: 9135 AQATI 9139



 Score = 39.9 bits (89), Expect = 0.41
 Identities = 43/158 (27%), Positives = 64/158 (40%), Gaps = 11/158 (6%)

Query: 134   GSPEPNVYWKKNGQTLLFDGDSRM----HLVDGGNLVIQDARQTDAGRYQCIARNAAG-- 187
             G P P V W KNG+TL  D + +M    HL    +L +    +  AG Y   A NA+G  
Sbjct: 10415 GKPMPKVTWSKNGETLKADKEFKMSQKRHLF---SLSLDAVTKLHAGNYGIHAANASGNT 10471

Query: 188   TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD-VLWRRSAGGGNMPL 246
             T E  +  L I   P  +   E +  +   S       GG P+ + V+ +R         
Sbjct: 10472 TAEIQLKILDIPGPPASVKLDEILSDRVKLSWEAPLVDGGSPITNYVVDKRETSRAEWAQ 10531

Query: 247   GRVKV-LDDGSLRLDNVILADEGEYSCEAENSVGAVSA 283
                K+  D     ++ +I   E ++   AEN  G   A
Sbjct: 10532 VSAKISRDTTECSVERLIEGHEYQFRVRAENHYGTGDA 10569



 Score = 39.5 bits (88), Expect = 0.55
 Identities = 35/123 (28%), Positives = 53/123 (43%), Gaps = 9/123 (7%)

Query: 411  IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTC 467
            I S AVF C  I     I  W  +G  + ++ +   T+DG    L + D+  SD+G YTC
Sbjct: 2675 IGSSAVFECQ-ISPSTAITTWMKDGSNIRESPKHKFTSDGKDRKLQIIDVQLSDTGEYTC 2733

Query: 468  VASSRHGKYVWSGALLVDS-PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQ 526
            VA   + +   +  L+V+  P+    +     + S L G P         D  V   W +
Sbjct: 2734 VAKLGNKEKTSTAKLVVEELPVKFTKNL--EEETSVLKGQPMYLTCELSKDKDVV--WKK 2789

Query: 527  NNK 529
            N K
Sbjct: 2790 NGK 2792



 Score = 39.5 bits (88), Expect = 0.55
 Identities = 69/310 (22%), Positives = 117/310 (37%), Gaps = 34/310 (10%)

Query: 304  VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
            V++G+         G+P+P + WS EG+   I  G+       T      T L ++++ +
Sbjct: 9358 VKAGDAVSIEAELLGKPQPEVKWSKEGDTRDISKGLRVQVETGT----NFTKLQLSNSRR 9413

Query: 364  NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA--VFPCTA 421
             D+   I+ +A N AG+     K+ V    DRP PI     S+ ++    +A  +     
Sbjct: 9414 GDTGKYII-TATNAAGTCSAEAKVNVL---DRPGPIRDLKVSDISIDRCKLAWEIPEDDG 9469

Query: 422  ICTPEPIIAWYFEGEALIQN-HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
             C     I    E +  + + H   +  +   V + L + +   +   A ++ G    +G
Sbjct: 9470 GCEIYNYIIEKCEAKRGVWSIHSAAIITNSAKVTR-LIEGNEYIFRVRAENKMG----AG 9524

Query: 481  ALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQV 540
              +    I     F R       P  P   +T    DT V + W   +  G   I GY +
Sbjct: 9525 PAVESESIIARTQFSR----PGAPDAP--EVTKITKDTMVVM-WCSPDNDGGKPITGYIL 9577

Query: 541  EVFSRETLSGNNTPRNSRGWVVIARRVHQ-THYVVKSLIPGITYMFIVRTENSHGLSGPS 599
            E      +           W  + +  +  T   V SL+P   Y F V+ EN  G+   S
Sbjct: 9578 EKKEEHAIR----------WAPVVKSPYAGTQMTVTSLLPNHEYQFRVKAENEIGVGDAS 9627

Query: 600  PVSDSVTVGD 609
              S + T  D
Sbjct: 9628 KPSRTFTARD 9637



 Score = 39.1 bits (87), Expect = 0.72
 Identities = 30/105 (28%), Positives = 41/105 (39%), Gaps = 11/105 (10%)

Query: 503   LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
             +PG P     + V    + ++W +    G S + GY +E             RNS  WV 
Sbjct: 10185 VPGEPLNCRINKVNKDCMFVAWDKPESDGGSPVTGYYIE----------RKERNSLLWVK 10234

Query: 563   IARRV-HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVT 606
                 V   T Y    LI G+ Y F V   N  G   PS  +D +T
Sbjct: 10235 ANDSVVRTTEYPCAGLIEGLEYTFRVSAINRAGQGKPSKKTDFIT 10279



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 39/146 (26%), Positives = 58/146 (39%), Gaps = 16/146 (10%)

Query: 160  VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK-----PYL---ITGPEDV 211
            V G   VI   ++    +++ IA NAAG  E       + +K     P L   ++  E +
Sbjct: 7713 VRGTKFVITGLKENALFKFRVIALNAAGLGEPGEVADALEMKDRTILPVLELDVSVKEKM 7772

Query: 212  VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVI----LADE 267
            V   G  +     V G P P + W R       P+    V++  S+    VI     A  
Sbjct: 7773 VIHAGGVIRILAYVSGQPPPVITWSRD----EYPVPSEAVIETTSISCSMVIKDCTRAQR 7828

Query: 268  GEYSCEAENSVGAVSASGYLTVYDPP 293
            G Y+  A+N  G V  S  + V D P
Sbjct: 7829 GVYTITAKNDGGEVKKSVIVEVLDVP 7854



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 29/109 (26%), Positives = 52/109 (47%), Gaps = 11/109 (10%)

Query: 367  RNTIVCSA--VNYAGSSFV-RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
            R+ I+  A  V      FV + KLTV    + PP   +    +QT+  ++ A+  C  + 
Sbjct: 3618 RDVIMTEAGEVKLTAKDFVTQAKLTV----NEPPVEFSKPLEDQTVEEEATAILECE-LS 3672

Query: 424  TPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVA 469
              +  + W+ +G+ + +  +  +  +G    L++KD    DS TYTC A
Sbjct: 3673 REKADVKWFRDGQEIRKTKKHEMVAEGRIRRLIIKDCSLDDSKTYTCDA 3721



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 37/118 (31%), Positives = 48/118 (40%), Gaps = 15/118 (12%)

Query: 497   AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556
             A   S  PGP     T  VT  S TLSW +    G S I+ Y +EV     L+G +    
Sbjct: 10973 AVRASEQPGPVMDFKTLLVTKDSCTLSWKKPISDGGSRIIAYVLEV-----LNGEDK--- 11024

Query: 557   SRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSL 614
                W  + R  +   Y  K L+ G  Y + V   N    SG  PV +   +  D N L
Sbjct: 11025 ---WKELLRSKNM-QYSAKDLVEGREYKYRVFATND---SGDGPVKELSVLAKDINVL 11075



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 31/109 (28%), Positives = 42/109 (38%), Gaps = 10/109 (9%)

Query: 499  DVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558
            +V + P  P       VT   V L W      G S + GY VE   RE         + +
Sbjct: 4845 NVIACPSAPKDFKVAEVTRHHVHLMWEAPEHDGGSPVSGYNVE--KREV--------SRK 4894

Query: 559  GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
             WV +   V    Y V  +I G  Y+F V   N  G   P+ + + V V
Sbjct: 4895 TWVKVISGVQDLEYTVTDVIEGKEYLFSVIACNKCGPGEPAYIDEPVNV 4943



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 37/129 (28%), Positives = 49/129 (37%), Gaps = 17/129 (13%)

Query: 504  PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
            PGPP   I  +VT+T++ +SW      G   ILGY VE      L G       + WV  
Sbjct: 6370 PGPPVPKIV-DVTNTTIDISWQPPLYNGGGEILGYHVE----RCLVG------EKDWVRC 6418

Query: 564  AR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSN 622
               R     Y V  L  G  Y   V   N  G   P  +++ V   +      E  GV  
Sbjct: 6419 TEFRCKDRKYTVTGLTEGADYNLRVYAVNEGGHGAPG-MTEPVQAKEPE----EAPGVEF 6473

Query: 623  STEYRNNIL 631
                RN ++
Sbjct: 6474 DISVRNGVI 6482



 Score = 37.5 bits (83), Expect = 2.2
 Identities = 27/100 (27%), Positives = 41/100 (41%), Gaps = 11/100 (11%)

Query: 500  VSSLPGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558
            V+  P PP  P+  + V    + +SW      G S I  Y +E   R+         N  
Sbjct: 8146 VADRPLPPEGPVVFDEVHRDHMVISWKPPLDDGGSEISNYIIE--KRDV--------NRD 8195

Query: 559  GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
             W  +     +TH  V  L+ G  Y+  +  EN +G+S P
Sbjct: 8196 MWTTVTSATTKTHCKVPKLVEGREYILRISAENMYGISDP 8235



 Score = 37.1 bits (82), Expect = 2.9
 Identities = 18/43 (41%), Positives = 24/43 (55%)

Query: 499  DVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541
            DV  +PGP     T NV+   ++L+WS     G S I+GY VE
Sbjct: 6559 DVMDVPGPVVDLKTVNVSKKMISLTWSDPLDNGGSDIMGYVVE 6601



 Score = 37.1 bits (82), Expect = 2.9
 Identities = 26/80 (32%), Positives = 40/80 (50%), Gaps = 10/80 (12%)

Query: 134   GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIARNAAGTRE 190
             G P P   WK+    ++    SR+ +    N   L+I+D  + D+G Y  +A N++G  E
Sbjct: 10018 GKPAPACQWKRGENNVV--SSSRLAVHKSQNMCVLIIKDVSRQDSGEYSLVAENSSGKIE 10075

Query: 191   SAIATLKIHIKPYLITGPED 210
                 TLKI I+   I GP +
Sbjct: 10076 Q---TLKIIIRD--IPGPPE 10090



 Score = 36.3 bits (80), Expect = 5.1
 Identities = 30/117 (25%), Positives = 50/117 (42%), Gaps = 10/117 (8%)

Query: 497  AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556
            A D   +P  P K      T  ++TL+W      G S I+GY +E   +++   +   RN
Sbjct: 6655 AVDPKGVPSAPEKLRYTERTKNTITLTWEAPRSDGGSPIIGYYIEKMRQDSNEYDVANRN 6714

Query: 557  SRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNS 613
                + I          +++L   + + F V+  N  G   PS  + SV + +D NS
Sbjct: 6715 LCKDLTI---------TLENLTENMMFDFRVKAVNEVGNGEPSK-AISVNIQEDENS 6761



 Score = 36.3 bits (80), Expect = 5.1
 Identities = 25/89 (28%), Positives = 42/89 (47%), Gaps = 10/89 (11%)

Query: 211  VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS------LRLDNVIL 264
            +  + G  +    RV G P P++ W + A      LGR K  +  +      L + + + 
Sbjct: 9063 LTVRAGQIINLVTRVKGRPDPEITWTKDA----RVLGRDKRTEMNNNFPLVELVIQDAVR 9118

Query: 265  ADEGEYSCEAENSVGAVSASGYLTVYDPP 293
            AD G+Y+ +A+NS G   A+  + V D P
Sbjct: 9119 ADYGKYAIQAKNSSGQAQATIIVNVLDIP 9147



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 32/132 (24%), Positives = 58/132 (43%), Gaps = 9/132 (6%)

Query: 177   RYQCIARNAAG---TRESAIATLKIHIKPY--LITGPE-DVVAQTGSSVTFQCRVGGDPL 230
             +Y+  A N +G    +E ++    I++ P   L   P  + +A+ GS+V  +  + G P 
Sbjct: 11048 KYRVFATNDSGDGPVKELSVLAKDINVLPSCDLRDLPNLNYIAKEGSNVRLKIPIIGKPT 11107

Query: 231   PDVLWRRSAGGGNMPLGRVKVLD---DGSLRLDNVILADEGEYSCEAENSVGAVSASGYL 287
             P V W++         GRV V     + +L + +    D  +Y+    NS G   ++ ++
Sbjct: 11108 PAVSWKKGEDENLTDTGRVCVESTAVNTTLLIRDCQRTDASKYTITLRNSAGTKESTIFV 11167

Query: 288   TVYDPPSINLSP 299
              V   P I   P
Sbjct: 11168 RVVGKPGIPNGP 11179



 Score = 35.5 bits (78), Expect = 8.9
 Identities = 39/164 (23%), Positives = 68/164 (41%), Gaps = 17/164 (10%)

Query: 209  EDVVAQT----GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDN 261
            +D+V Q     GSS  F+C++   P   +      G       + K   DG    L++ +
Sbjct: 2665 QDIVLQEAESIGSSAVFECQIS--PSTAITTWMKDGSNIRESPKHKFTSDGKDRKLQIID 2722

Query: 262  VILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN---SVNVESGNVARFTCTATG 318
            V L+D GEY+C A+      +++  L V + P +  + N     +V  G     TC  + 
Sbjct: 2723 VQLSDTGEYTCVAKLGNKEKTSTAKLVVEELP-VKFTKNLEEETSVLKGQPMYLTCELS- 2780

Query: 319  RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
              +  + W   G      PG  + + +   +   VT+  +ND D
Sbjct: 2781 -KDKDVVWKKNGKELKEIPG--KIQINIIGLQRAVTIQDMNDDD 2821



 Score = 35.5 bits (78), Expect = 8.9
 Identities = 31/114 (27%), Positives = 44/114 (38%), Gaps = 11/114 (9%)

Query: 497  AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556
            A D  + PGPP       V+   V L W   N  G   I  Y +E   +E +        
Sbjct: 5539 AKDTFTTPGPPYALTVVEVSKRHVDLKWEPPNSDGGRPITKYVIE--KKEKVGTR----- 5591

Query: 557  SRGWVVIARRV-HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
               WV   +    ++ Y V  +  G    F VR EN  G+  PS  +  +T+ D
Sbjct: 5592 ---WVKSGKTSGPESKYRVTDVDEGTEVQFQVRAENEAGVGHPSEPTVIMTIED 5642



 Score = 35.5 bits (78), Expect = 8.9
 Identities = 30/107 (28%), Positives = 48/107 (44%), Gaps = 11/107 (10%)

Query: 504  PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
            PGPP+     + + +   L W++ ++ G S ILGY VE+      SG      S  W  I
Sbjct: 8950 PGPPSNIKLKDWSKSYADLVWTKPSRDGGSPILGYVVEI----QRSG------SAQWDKI 8999

Query: 564  AR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
             +  +    + V  L  GI Y F ++  N  G   P  ++++V   D
Sbjct: 9000 NKDLIKFCAFRVPGLNEGIEYRFRIKASNKVGDGEPRELTETVLAKD 9046


>UniRef50_Q6UXM1 Cluster: Leucine-rich repeats and
           immunoglobulin-like domains protein 3 precursor; n=43;
           Euteleostomi|Rep: Leucine-rich repeats and
           immunoglobulin-like domains protein 3 precursor - Homo
           sapiens (Human)
          Length = 1119

 Score =  106 bits (255), Expect = 3e-21
 Identities = 77/298 (25%), Positives = 136/298 (45%), Gaps = 26/298 (8%)

Query: 107 REEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVY-WKKNGQTLLFDGDSR--MHL-VDG 162
           + +  ++PE++ + +G  +   C     S  P  + WKK+ + LL D +     HL   G
Sbjct: 498 KPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNE-LLHDAEMENYAHLRAQG 556

Query: 163 GNLV-------IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT 215
           G ++       +++      G+YQC+  N  G+  S  A L +++ P     P D+  + 
Sbjct: 557 GEVMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRA 616

Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL----DDGSLRLDNVILADEGEYS 271
           G+    +C   G P P + W++  GG + P  R + +    +D    + +V + D G YS
Sbjct: 617 GAMARLECAAVGHPAPQIAWQKD-GGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYS 675

Query: 272 CEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGN 331
           C A+NS G++SA+  LTV + PS         V  G  A   C A G P P + W+ + +
Sbjct: 676 CTAQNSAGSISANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDS 735

Query: 332 RTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389
             ++      +++   A   G  +L I D+D +D+     C   N  G+     +L+V
Sbjct: 736 PLVV-----TERHFFAA---GNQLLIIVDSDVSDA-GKYTCEMSNTLGTERGNVRLSV 784



 Score = 88.2 bits (209), Expect = 1e-15
 Identities = 64/220 (29%), Positives = 93/220 (42%), Gaps = 13/220 (5%)

Query: 257 LRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315
           LRL  V  A EG+Y C   N  G+  S    LTV   PS   +P  + + +G +AR  C 
Sbjct: 566 LRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLECA 625

Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
           A G P P + W  +G     FP     + H     D   ++ +    K +      C+A 
Sbjct: 626 AVGHPAPQIAWQKDGGTD--FPAARERRMHVMPEDDVFFIVDV----KIEDIGVYSCTAQ 679

Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG 435
           N AGS      LTV        P++     ++T+     AV  C A  +P P + W  + 
Sbjct: 680 NSAGSISANATLTVLETPSFLRPLL-----DRTVTKGETAVLQCIAGGSPPPKLNWTKDD 734

Query: 436 EALIQNHRRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
             L+   R      +  L++ D D SD+G YTC  S+  G
Sbjct: 735 SPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLG 774



 Score = 87.4 bits (207), Expect = 2e-15
 Identities = 63/194 (32%), Positives = 91/194 (46%), Gaps = 16/194 (8%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG---VLVVSDTHRSILP 62
           +T    P   + P+D+T+     A L C A G P+P I W K G        +    ++P
Sbjct: 597 LTVNMLPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMP 656

Query: 63  AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQ 121
              +FF+     ++  D GVY C A NS G+  S NATL   VL     L P   +   +
Sbjct: 657 EDDVFFI--VDVKI-EDIGVYSCTAQNSAGSI-SANATL--TVLETPSFLRPLLDRTVTK 710

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQ 179
           G+T VL+C+   GSP P + W K+   L+    +  H    GN  L+I D+  +DAG+Y 
Sbjct: 711 GETAVLQCI-AGGSPPPKLNWTKDDSPLVV---TERHFFAAGNQLLIIVDSDVSDAGKYT 766

Query: 180 CIARNAAGTRESAI 193
           C   N  GT    +
Sbjct: 767 CEMSNTLGTERGNV 780



 Score = 82.2 bits (194), Expect = 8e-14
 Identities = 62/216 (28%), Positives = 97/216 (44%), Gaps = 5/216 (2%)

Query: 81  GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
           G Y C  +N +G++ S  A L V +L   F   P       G    LEC    G P P +
Sbjct: 577 GKYQCVISNHFGSSYSVKAKLTVNML-PSFTKTPMDLTIRAGAMARLECAAV-GHPAPQI 634

Query: 141 YWKKNGQT-LLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
            W+K+G T      + RMH++   ++  I D +  D G Y C A+N+AG+  SA ATL +
Sbjct: 635 AWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSI-SANATLTV 693

Query: 199 HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLR 258
              P  +    D     G +   QC  GG P P + W +      +         +  L 
Sbjct: 694 LETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLI 753

Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
           + +  ++D G+Y+CE  N++G    +  L+V   P+
Sbjct: 754 IVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPTPT 789



 Score = 62.9 bits (146), Expect = 5e-08
 Identities = 55/218 (25%), Positives = 91/218 (41%), Gaps = 16/218 (7%)

Query: 277 SVGAVSASGYLTVYDP-PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII 335
           S+ AVS  G++    P P I + P + +   G+   F C+A    +  M ++ + +  ++
Sbjct: 482 SIFAVSPDGFVCDDFPKPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNELL 541

Query: 336 FPGMSRDKYHATA----VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF-VRGKLTVT 390
                 +  H  A    V +  T+L + + +   S     C   N+ GSS+ V+ KLTV 
Sbjct: 542 HDAEMENYAHLRAQGGEVMEYTTILRLREVEFA-SEGKYQCVISNHFGSSYSVKAKLTVN 600

Query: 391 SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG----EALIQNHRRNV 446
                  P  T  P + T+   +MA   C A+  P P IAW  +G     A  +     +
Sbjct: 601 M-----LPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVM 655

Query: 447 TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
             D    + D+   D G Y+C A +  G    +  L V
Sbjct: 656 PEDDVFFIVDVKIEDIGVYSCTAQNSAGSISANATLTV 693



 Score = 56.0 bits (129), Expect = 6e-06
 Identities = 39/95 (41%), Positives = 47/95 (49%), Gaps = 6/95 (6%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFF 68
           E P  +   LD TV + + A L C AGGSP P + W K    LVV++ H     A G   
Sbjct: 695 ETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERH---FFAAGNQL 751

Query: 69  LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103
           L      V SDAG Y CE +N+ GT R  N  L V
Sbjct: 752 LIIVDSDV-SDAGKYTCEMSNTLGTERG-NVRLSV 784


>UniRef50_Q8UVD6 Cluster: Brother of CDO; n=2; Danio rerio|Rep:
           Brother of CDO - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 1032

 Score =  106 bits (254), Expect = 4e-21
 Identities = 89/344 (25%), Positives = 146/344 (42%), Gaps = 29/344 (8%)

Query: 1   MSDDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGG--VLVVSDTH 57
           + D    + + P   E+P  V        TL C A   P+   I W+  G  +    D  
Sbjct: 29  LQDSNAVTDDVPVFTEEPFSVVQKLGGSVTLRCSA--LPNHVNISWHLNGRELPAGGDEE 86

Query: 58  RSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK 117
             +L   G  ++ +     +   G Y C AT S G+  S  A +  A LR+    EP+ +
Sbjct: 87  LGVLVRPGSLYIPSL---TNLTVGRYQCVATTSVGSCASVPANVTAAKLRD---FEPDDQ 140

Query: 118 QSAQ---GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTD 174
           Q  +   G+T V+EC  P   P+  V +    Q  L        ++  GNL I +A + D
Sbjct: 141 QEIEVDEGNTAVIECHLPESQPKAQVRYSVK-QEWLETSKGNYLIMPSGNLQIANATRDD 199

Query: 175 AGRYQCIARNAAGTR-ESAIATLKIHIK------PYLITGP--EDVVAQTGSSVTFQCRV 225
            G Y C A N      +++ +T ++ I+        +I  P    ++   G  +  +C  
Sbjct: 200 EGPYICAAYNPVTQEIKTSTSTDRLRIRRSTSEAARIIYPPASRSIMVNKGQRLVLECVA 259

Query: 226 GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASG 285
            G P P V W +  G         + L   +L +D    +D G Y C A+N +G+ S++ 
Sbjct: 260 SGIPTPQVTWAKD-GLDLRNHNNTRFLLS-NLLIDAASESDSGTYVCLADNGIGSTSSAQ 317

Query: 286 YL---TVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326
            L    V++PP + +     +V  G+  RF+C   G+P PT+ W
Sbjct: 318 VLYDVQVFEPPQVRVELQQQDVAWGDTVRFSCQVRGKPAPTVVW 361



 Score = 91.1 bits (216), Expect = 2e-16
 Identities = 88/288 (30%), Positives = 132/288 (45%), Gaps = 23/288 (7%)

Query: 20  DVTVARHQPATLNCRAGGS-PSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
           ++ V     A + C    S P   +R+  K   L  S  +  I+P+G L    AT     
Sbjct: 142 EIEVDEGNTAVIECHLPESQPKAQVRYSVKQEWLETSKGNYLIMPSGNLQIANATR---- 197

Query: 78  SDAGVYWCEATNSYGTA-RSRNATLHVAVLR---EEFRL-EPESKQSA---QGDTVVLEC 129
            D G Y C A N      ++  +T  + + R   E  R+  P + +S    +G  +VLEC
Sbjct: 198 DDEGPYICAAYNPVTQEIKTSTSTDRLRIRRSTSEAARIIYPPASRSIMVNKGQRLVLEC 257

Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
           +   G P P V W K+G  L    ++R  L    NL+I  A ++D+G Y C+A N  G+ 
Sbjct: 258 VAS-GIPTPQVTWAKDGLDLRNHNNTRFLL---SNLLIDAASESDSGTYVCLADNGIGST 313

Query: 190 ESAIATLKIHI--KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
            SA     + +   P +    +      G +V F C+V G P P V+W  +A   + P  
Sbjct: 314 SSAQVLYDVQVFEPPQVRVELQQQDVAWGDTVRFSCQVRGKPAPTVVWLHNAQPLS-PSP 372

Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPS 294
           R +V     LR+ NV   D+G Y C AEN VG + +A+  LT+   PS
Sbjct: 373 RHRV-SAQVLRVLNVGPQDDGMYQCMAENGVGSSQAATRLLTLPTVPS 419



 Score = 79.4 bits (187), Expect = 6e-13
 Identities = 90/378 (23%), Positives = 142/378 (37%), Gaps = 29/378 (7%)

Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH-LVDGGNLVIQ 168
           F  EP S     G +V L C         N+ W  NG+ L   GD  +  LV  G+L I 
Sbjct: 42  FTEEPFSVVQKLGGSVTLRCSALPN--HVNISWHLNGRELPAGGDEELGVLVRPGSLYIP 99

Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVG- 226
                  GRYQC+A  + G+  S  A +    ++ +     +++    G++   +C +  
Sbjct: 100 SLTNLTVGRYQCVATTSVGSCASVPANVTAAKLRDFEPDDQQEIEVDEGNTAVIECHLPE 159

Query: 227 GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY 286
             P   V +           G   ++  G+L++ N    DEG Y C A N V     +  
Sbjct: 160 SQPKAQVRYSVKQEWLETSKGNYLIMPSGNLQIANATRDDEGPYICAAYNPVTQEIKTST 219

Query: 287 LT--------VYDPPSINLSP--NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF 336
            T          +   I   P   S+ V  G      C A+G P P + W+ +       
Sbjct: 220 STDRLRIRRSTSEAARIIYPPASRSIMVNKGQRLVLECVASGIPTPQVTWAKD------- 272

Query: 337 PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP 396
            G+    ++ T     ++ L I+   ++DS  T VC A N  GS+     L      +  
Sbjct: 273 -GLDLRNHNNTRFL--LSNLLIDAASESDS-GTYVCLADNGIGSTSSAQVLYDVQVFE-- 326

Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKD 456
           PP +      Q +       F C     P P + W    + L  + R  V+     VL +
Sbjct: 327 PPQVRVELQQQDVAWGDTVRFSCQVRGKPAPTVVWLHNAQPLSPSPRHRVSAQVLRVL-N 385

Query: 457 LDKSDSGTYTCVASSRHG 474
           +   D G Y C+A +  G
Sbjct: 386 VGPQDDGMYQCMAENGVG 403



 Score = 39.5 bits (88), Expect = 0.55
 Identities = 55/227 (24%), Positives = 88/227 (38%), Gaps = 25/227 (11%)

Query: 502 SLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV 561
           S P  P +P     T+TS  ++W            G+ ++ F  E        + S  W 
Sbjct: 577 SPPEAPDRPTVSMATETSAYVTWIPRGN------RGFPIQSFRVE---HKKLRKGSGDWE 627

Query: 562 VIARRVHQTHYVVK--SLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTG 619
           V    +  +   V+   L  G +Y F V   N  G S PS  S + TV         G+G
Sbjct: 628 VAVNNIPPSRLSVEVTGLEKGTSYKFRVLAVNVLGASPPSAPSKAYTV--------VGSG 679

Query: 620 VSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYE 679
             N        +T +  E I  T I    +K  +  LN   + G +I++RP D+   + +
Sbjct: 680 PPNRRPIDGPYITYN--EAINETTI---ILKWTYTPLNNTPIYGFYIFYRPTDSDN-DSD 733

Query: 680 MKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQT 726
            K  +   D     IT L+  T Y+  +  F +  E +  N  + +T
Sbjct: 734 YKKDVVEGDRYWHSITDLQPETAYDIKMQCFNEGGESEFGNVVILET 780


>UniRef50_Q4RRS5 Cluster: Chromosome 16 SCAF15002, whole genome
           shotgun sequence; n=4; Euteleostomi|Rep: Chromosome 16
           SCAF15002, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 1278

 Score =  106 bits (254), Expect = 4e-21
 Identities = 134/522 (25%), Positives = 204/522 (39%), Gaps = 60/522 (11%)

Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT 173
           P+  ++ +G + VL C   +G+P+P + W + G+ L  +    +  V  G+L I    + 
Sbjct: 151 PQYVEAKEGGSTVLSC-SAQGNPKPMISWLREGEELATNAKYTVRKVHDGSLTILGITRD 209

Query: 174 DAGRYQCIARNAAG-----TR---ESAIATLKIHIK-----PYLITGPEDVVAQTGSSVT 220
           D G Y C A +  G     TR   +    +  +H K     PY+++ PE+V      +  
Sbjct: 210 DRGAYTCRAYSDQGEVLHTTRLLVQGIAISPALHYKSTLWPPYIVSPPENVTVNISQNAL 269

Query: 221 FQCRV---GGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAEN 276
           F C+     G+      W          L  RV++L DG+L +  V   D G+Y+C   N
Sbjct: 270 FTCQAEAYPGNLTYTWFWEEDNVYFKNDLKLRVRILIDGTLIIFRVKPEDAGKYTCTPSN 329

Query: 277 SVG-AVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPT-MFWSVEGNRTI 334
           S+G + SAS +LTV  P  +   P  + V         C     P  T + W  +G    
Sbjct: 330 SLGISPSASAHLTVQYPARVINMPPVIYVPRKLPGIIRCPVDANPPVTSVKWEKDG---- 385

Query: 335 IFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394
            +P +  +KY   ++    ++     T+  DS  T  C   N  G+  +  + T+   D 
Sbjct: 386 -YP-LRVEKYPGWSLTPDGSIRVAEATE--DSLGTYTCVPYNALGTMGMSPQATLVLKD- 440

Query: 395 RPPPIITNGPSNQ-TLPIKSMAVFPCTAICTPE-PIIAWYFEGEALIQNHRRNVTNDGTL 452
             PP     P  +         V PC A   P+ P I W   G+     H  NV   G+L
Sbjct: 441 --PPYFNVRPGGEYRQEAGRELVIPCAASGDPDIPTITWRKVGKPSKSKH--NVLPSGSL 496

Query: 453 VLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPIT 512
               L K D G + CVA++       S  +LV   I  + H     ++  LP        
Sbjct: 497 QFLSLSKEDHGEWECVATNVVTSITASTRILV---IGTSPH--APGNIHVLP-------- 543

Query: 513 HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHY 572
              + TS  +SW      G            S+ T  G   P +   W  +     QT  
Sbjct: 544 ---SMTSANVSWEPGYDGGFEQTFSVWYGPVSKRTDFG---PHD---WHSMPVSGAQTWL 594

Query: 573 VVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSL 614
           VV  L PG  Y F V  +N     G  P S+ VTV    + L
Sbjct: 595 VVPGLEPGTEYQFSVLAQNK---LGTGPFSEVVTVNTTGSPL 633



 Score = 96.7 bits (230), Expect = 3e-18
 Identities = 82/286 (28%), Positives = 118/286 (41%), Gaps = 16/286 (5%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIR---WYKGGVLVVSDTHRS--ILPAGGL 66
           PYI+  P +VTV   Q A   C+A   P        W +  V   +D      IL  G L
Sbjct: 251 PYIVSPPENVTVNISQNALFTCQAEAYPGNLTYTWFWEEDNVYFKNDLKLRVRILIDGTL 310

Query: 67  FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
              R        DAG Y C  +NS G + S +A L V        + P      +   ++
Sbjct: 311 IIFRVKP----EDAGKYTCTPSNSLGISPSASAHLTVQYPARVINMPPVIYVPRKLPGII 366

Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
             C      P  +V W+K+G  L  +      L   G++ + +A +   G Y C+  NA 
Sbjct: 367 -RCPVDANPPVTSVKWEKDGYPLRVEKYPGWSLTPDGSIRVAEATEDSLGTYTCVPYNAL 425

Query: 187 GTR-ESAIATLKIHIKPYLITGPEDVVAQ-TGSSVTFQCRVGGDP-LPDVLWRRSAGGGN 243
           GT   S  ATL +   PY    P     Q  G  +   C   GDP +P + WR+    G 
Sbjct: 426 GTMGMSPQATLVLKDPPYFNVRPGGEYRQEAGRELVIPCAASGDPDIPTITWRKV---GK 482

Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
               +  VL  GSL+  ++   D GE+ C A N V +++AS  + V
Sbjct: 483 PSKSKHNVLPSGSLQFLSLSKEDHGEWECVATNVVTSITASTRILV 528



 Score = 69.3 bits (162), Expect = 6e-10
 Identities = 98/401 (24%), Positives = 149/401 (37%), Gaps = 55/401 (13%)

Query: 111 RLEPESKQSAQGDTVVLEC--LPPRGSPEPN--VYWKKNGQTLLF-------------DG 153
           R EP    +  G++V+L C   PP    +P   V W K G  + F             + 
Sbjct: 32  REEPRFVTARAGESVILGCDVSPPLDGQQPPYVVEWFKFGVPIPFFINFRFYPPHVDPEY 91

Query: 154 DSRMHLVDGGNLVIQDARQTDAGRYQC----IARNAAGTRESAIATLKIHIKP-YLITGP 208
             R  L    +L I   R  D G Y+C    + +        +   L ++  P +  T P
Sbjct: 92  TGRASLHGKASLQIDPVRSEDQGWYECRVLMLEQQYDTFHNGSWVHLTVNAPPSFTATPP 151

Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDGSLRLDNVILADE 267
           + V A+ G S    C   G+P P + W R            V+ + DGSL +  +   D 
Sbjct: 152 QYVEAKEGGSTVLSCSAQGNPKPMISWLREGEELATNAKYTVRKVHDGSLTILGITRDDR 211

Query: 268 GEYSCEAENSVGAV--------------SASGYLTVYDPPSINLSPNSVNVESGNVARFT 313
           G Y+C A +  G V               A  Y +   PP I   P +V V     A FT
Sbjct: 212 GAYTCRAYSDQGEVLHTTRLLVQGIAISPALHYKSTLWPPYIVSPPENVTVNISQNALFT 271

Query: 314 CTATGRP-EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
           C A   P   T  W  E +       +   K     + DG  ++      K +      C
Sbjct: 272 CQAEAYPGNLTYTWFWEEDNVYFKNDL---KLRVRILIDGTLIIF---RVKPEDAGKYTC 325

Query: 373 SAVNYAG-SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI--I 429
           +  N  G S      LTV     + P  + N P    +P K   +  C     P P+  +
Sbjct: 326 TPSNSLGISPSASAHLTV-----QYPARVINMPPVIYVPRKLPGIIRCPVDANP-PVTSV 379

Query: 430 AWYFEGEAL-IQNHRR-NVTNDGTLVLKDLDKSDSGTYTCV 468
            W  +G  L ++ +   ++T DG++ + +  +   GTYTCV
Sbjct: 380 KWEKDGYPLRVEKYPGWSLTPDGSIRVAEATEDSLGTYTCV 420



 Score = 60.1 bits (139), Expect = 4e-07
 Identities = 37/128 (28%), Positives = 60/128 (46%), Gaps = 4/128 (3%)

Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNV--TNDGTLV 453
           PP      P           V  C+A   P+P+I+W  EGE L  N +  V   +DG+L 
Sbjct: 143 PPSFTATPPQYVEAKEGGSTVLSCSAQGNPKPMISWLREGEELATNAKYTVRKVHDGSLT 202

Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS-PINPNIHFFRAADVSSLPGPPTKPIT 512
           +  + + D G YTC A S  G+ + +  LLV    I+P +H+        +  PP + +T
Sbjct: 203 ILGITRDDRGAYTCRAYSDQGEVLHTTRLLVQGIAISPALHYKSTLWPPYIVSPP-ENVT 261

Query: 513 HNVTDTSV 520
            N++  ++
Sbjct: 262 VNISQNAL 269


>UniRef50_Q1ENI8 Cluster: Peroxidasin (Drosophila peroxidase)
           homolog protein 1; n=2; Caenorhabditis|Rep: Peroxidasin
           (Drosophila peroxidase) homolog protein 1 -
           Caenorhabditis elegans
          Length = 1285

 Score =  106 bits (254), Expect = 4e-21
 Identities = 63/183 (34%), Positives = 88/183 (48%), Gaps = 4/183 (2%)

Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ 168
           +F  +P      +G  V + C    G+P+P + W  NG+  +     ++ L     L I 
Sbjct: 316 QFTYKPRDNSFREGSEVKVNC-EVMGNPKPTINWYHNGKRFISSRKRQLGL-SNNVLRIY 373

Query: 169 DARQTDAGRYQCIARNAAG-TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGG 227
              + D+GRY C A N+ G  R +    L   + P +  GP+ V    G SV F C+  G
Sbjct: 374 PFLEEDSGRYTCEAVNSVGKVRHAFSLDLISSVPPNIYEGPQSVSQNLGGSVVFVCKANG 433

Query: 228 DPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGY 286
           +P+PD  W           GR  V DDG+ LR+ N+   DEG YSC A N VGA+SA   
Sbjct: 434 NPVPDYTWSFDGSTIGHIKGRFMVSDDGTELRISNIEKKDEGYYSCMAGNPVGAMSADAK 493

Query: 287 LTV 289
           LTV
Sbjct: 494 LTV 496



 Score = 81.4 bits (192), Expect = 1e-13
 Identities = 63/196 (32%), Positives = 85/196 (43%), Gaps = 10/196 (5%)

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDN 261
           P     P D   + GS V   C V G+P P + W  +         R   L +  LR+  
Sbjct: 315 PQFTYKPRDNSFREGSEVKVNCEVMGNPKPTINWYHNGKRFISSRKRQLGLSNNVLRIYP 374

Query: 262 VILADEGEYSCEAENSVGAVSASGYLTVYD--PPSINLSPNSVNVESGNVARFTCTATGR 319
            +  D G Y+CEA NSVG V  +  L +    PP+I   P SV+   G    F C A G 
Sbjct: 375 FLEEDSGRYTCEAVNSVGKVRHAFSLDLISSVPPNIYEGPQSVSQNLGGSVVFVCKANGN 434

Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379
           P P   WS +G+ TI   G  + ++    V D  T L I++ +K D      C A N  G
Sbjct: 435 PVPDYTWSFDGS-TI---GHIKGRF---MVSDDGTELRISNIEKKD-EGYYSCMAGNPVG 486

Query: 380 SSFVRGKLTVTSDDDR 395
           +     KLTV   + R
Sbjct: 487 AMSADAKLTVIGGETR 502



 Score = 75.8 bits (178), Expect = 7e-12
 Identities = 54/188 (28%), Positives = 80/188 (42%), Gaps = 5/188 (2%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
           +P    +P D +        +NC   G+P P I WY  G   +S   R +  +  +  LR
Sbjct: 314 SPQFTYKPRDNSFREGSEVKVNCEVMGNPKPTINWYHNGKRFISSRKRQLGLSNNV--LR 371

Query: 71  ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
             +  +  D+G Y CEA NS G  R   +   ++ +       P+S     G +VV  C 
Sbjct: 372 -IYPFLEEDSGRYTCEAVNSVGKVRHAFSLDLISSVPPNIYEGPQSVSQNLGGSVVFVC- 429

Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
              G+P P+  W  +G T+       M   DG  L I +  + D G Y C+A N  G   
Sbjct: 430 KANGNPVPDYTWSFDGSTIGHIKGRFMVSDDGTELRISNIEKKDEGYYSCMAGNPVGAM- 488

Query: 191 SAIATLKI 198
           SA A L +
Sbjct: 489 SADAKLTV 496



 Score = 64.1 bits (149), Expect = 2e-08
 Identities = 53/184 (28%), Positives = 76/184 (41%), Gaps = 14/184 (7%)

Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
           P     P   +   G+  +  C   G P+PT+ W   G R I     SR +    +    
Sbjct: 315 PQFTYKPRDNSFREGSEVKVNCEVMGNPKPTINWYHNGKRFI----SSRKRQLGLSN--- 367

Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
             VL I    + DS     C AVN  G       L + S     PP I  GP + +  + 
Sbjct: 368 -NVLRIYPFLEEDS-GRYTCEAVNSVGKVRHAFSLDLISS---VPPNIYEGPQSVSQNLG 422

Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGT-LVLKDLDKSDSGTYTCVAS 470
              VF C A   P P   W F+G  +     R  V++DGT L + +++K D G Y+C+A 
Sbjct: 423 GSVVFVCKANGNPVPDYTWSFDGSTIGHIKGRFMVSDDGTELRISNIEKKDEGYYSCMAG 482

Query: 471 SRHG 474
           +  G
Sbjct: 483 NPVG 486



 Score = 46.8 bits (106), Expect = 0.004
 Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 1/97 (1%)

Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNV-TNDGTLVLKD 456
           P  T  P + +    S     C  +  P+P I WY  G+  I + +R +  ++  L +  
Sbjct: 315 PQFTYKPRDNSFREGSEVKVNCEVMGNPKPTINWYHNGKRFISSRKRQLGLSNNVLRIYP 374

Query: 457 LDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIH 493
             + DSG YTC A +  GK   + +L + S + PNI+
Sbjct: 375 FLEEDSGRYTCEAVNSVGKVRHAFSLDLISSVPPNIY 411


>UniRef50_UPI0000DB6DA9 Cluster: PREDICTED: similar to CG32387-PB,
           isoform B; n=1; Apis mellifera|Rep: PREDICTED: similar
           to CG32387-PB, isoform B - Apis mellifera
          Length = 829

 Score =  105 bits (253), Expect = 6e-21
 Identities = 89/339 (26%), Positives = 141/339 (41%), Gaps = 23/339 (6%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
           + S   P I E+ + ++        + C A G+P+P  RWY       +     +  + G
Sbjct: 249 IRSTMPPMINEKVVYMSARLKDTVVIPCVAYGNPTPTNRWYYNR----NQREEPVEDSSG 304

Query: 66  LFFLR----ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
            + +R       G   SD G Y C A+NS G + S    L V+       ++P  +    
Sbjct: 305 HYVVRDGSLIIQGVQESDGGSYMCTASNSEG-SESMEVRLTVSA-PLNVHVQPSIQTVDL 362

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
           G    L C    G P+  +YW K+GQ L     +R+  V    + +    + D G YQC 
Sbjct: 363 GKAAHLTC-SASGFPQAALYWLKDGQPL--RTGARIRAVSRERISVMSVAREDRGMYQCF 419

Query: 182 ARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA- 239
            RN     +  IA L++  I P L+    +   QTG SV+ +C   G+P P + W     
Sbjct: 420 VRNEYEMAQ-GIAELRLGEIAPQLVYRFIEQTMQTGPSVSLKCSAAGNPTPQISWLLDGF 478

Query: 240 ---GGGNMPLGR-VKVLDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
                  + +G+ V V  D    + + +V   D GEY C A +  G  S S  L +Y  P
Sbjct: 479 PLPQNDRLLIGQYVTVYGDVISHVNISSVKSEDGGEYECIASSRAGEASHSARLNIYGLP 538

Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332
            +    ++V+  +G      C   G P  ++ W  +G R
Sbjct: 539 YVR-PMSTVSAVAGKQFHIKCPVAGYPIESIVWEKDGVR 576



 Score =  103 bits (247), Expect = 3e-20
 Identities = 123/521 (23%), Positives = 211/521 (40%), Gaps = 66/521 (12%)

Query: 13  YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK--GGVLVVSDTHRSILPAGGLFF-- 68
           ++ E P  V         ++C   G+P+P + W    GG +      R +L  G + F  
Sbjct: 27  FVSEPPSRVEFTNVNGGRVDCTVRGNPAPTVDWLAADGGSITSIPGIRHVLGNGTIHFPG 86

Query: 69  LRATHGRVHSDAGVYWCEATNSYGTARSRNATL--------------HV-------AVLR 107
             A   R      +Y C A NS G   SR+ T+              H+        ++ 
Sbjct: 87  FEAEVFRQDVHWAIYKCSAVNSVGAIVSRDVTVRAVCGLFVVFQAMAHIPRRPGVWGMVN 146

Query: 108 EEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVY--WKKNGQTLLFD---GDSRMHLVDG 162
           + +  E +      G+ V++ C  P    +      W +     ++    GD + H++  
Sbjct: 147 QRYDPEVQCPGGFLGNNVLMRCNVPSFVRDHVTITSWLQEPSFNIYPSTMGDGKYHMLSS 206

Query: 163 GNLVIQDARQTDAGR-YQCIARNAAGTRESAIATL--KIHIKPYLITGP----EDVV--- 212
           G L+I +  + DA R Y+C   +   T+E+ +++   ++ +     T P    E VV   
Sbjct: 207 GELMILNITREDAERTYRCRTHHRL-TQETVVSSNVGRLQLTEIRSTMPPMINEKVVYMS 265

Query: 213 AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK---VLDDGSLRLDNVILADEGE 269
           A+   +V   C   G+P P   W  +      P+       V+ DGSL +  V  +D G 
Sbjct: 266 ARLKDTVVIPCVAYGNPTPTNRWYYNRNQREEPVEDSSGHYVVRDGSLIIQGVQESDGGS 325

Query: 270 YSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVE 329
           Y C A NS G+ S    LTV  P ++++ P+   V+ G  A  TC+A+G P+  ++W  +
Sbjct: 326 YMCTASNSEGSESMEVRLTVSAPLNVHVQPSIQTVDLGKAAHLTCSASGFPQAALYWLKD 385

Query: 330 GNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389
           G      P  +  +  A +  + ++V+++      + R    C   N       +G   +
Sbjct: 386 GQ-----PLRTGARIRAVS-RERISVMSV----AREDRGMYQCFVRN--EYEMAQGIAEL 433

Query: 390 TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR----RN 445
              +  P  +       QT+         C+A   P P I+W  +G  L QN R    + 
Sbjct: 434 RLGEIAPQLVYRF--IEQTMQTGPSVSLKCSAAGNPTPQISWLLDGFPLPQNDRLLIGQY 491

Query: 446 VTNDGTLV----LKDLDKSDSGTYTCVASSRHGKYVWSGAL 482
           VT  G ++    +  +   D G Y C+ASSR G+   S  L
Sbjct: 492 VTVYGDVISHVNISSVKSEDGGEYECIASSRAGEASHSARL 532



 Score = 96.7 bits (230), Expect = 3e-18
 Identities = 97/420 (23%), Positives = 172/420 (40%), Gaps = 37/420 (8%)

Query: 123 DTVVLECLPPRGSPEPNVYW--KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
           DTVV+ C+   G+P P   W   +N +    +  S  ++V  G+L+IQ  +++D G Y C
Sbjct: 270 DTVVIPCVA-YGNPTPTNRWYYNRNQREEPVEDSSGHYVVRDGSLIIQGVQESDGGSYMC 328

Query: 181 IARNAAGT-----RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
            A N+ G+     R +  A L +H++P + T         G +    C   G P   + W
Sbjct: 329 TASNSEGSESMEVRLTVSAPLNVHVQPSIQT------VDLGKAAHLTCSASGFPQAALYW 382

Query: 236 RRSAGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-PP 293
            +   G  +  G R++ +    + + +V   D G Y C   N          L + +  P
Sbjct: 383 LKD--GQPLRTGARIRAVSRERISVMSVAREDRGMYQCFVRNEYEMAQGIAELRLGEIAP 440

Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDK----YHATAV 349
            +        +++G      C+A G P P + W ++G     FP    D+     + T  
Sbjct: 441 QLVYRFIEQTMQTGPSVSLKCSAAGNPTPQISWLLDG-----FPLPQNDRLLIGQYVTVY 495

Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409
            D ++ + I+   K++      C A + AG +    +L +       P    +  + +  
Sbjct: 496 GDVISHVNISSV-KSEDGGEYECIASSRAGEASHSARLNIYGLPYVRPMSTVSAVAGKQF 554

Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDK-SDSGTYTCV 468
            IK      C     P   I W  +G  L  N R+ V N G+L +  + + +D GTYTC 
Sbjct: 555 HIK------CPVAGYPIESIVWEKDGVRLPTNMRQRVAN-GSLFIDTVQRAADQGTYTCT 607

Query: 469 ASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNN 528
           A ++H  +    ++ V   + P I  F  A   ++    +        D  +T +W ++N
Sbjct: 608 ARNKH-NFTSQRSVEVRVLVPPKITPFSFARDLNVGDRTSVQCVVVTGDLPLTFTWLKDN 666



 Score = 83.8 bits (198), Expect = 3e-14
 Identities = 84/320 (26%), Positives = 130/320 (40%), Gaps = 21/320 (6%)

Query: 17  QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV 76
           QP   TV   + A L C A G P  A+ W K G  + +      +    +  +       
Sbjct: 354 QPSIQTVDLGKAAHLTCSASGFPQAALYWLKDGQPLRTGARIRAVSRERISVMSV----A 409

Query: 77  HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
             D G+Y C   N Y  A+   A L +  +  +       +    G +V L+C    G+P
Sbjct: 410 REDRGMYQCFVRNEYEMAQG-IAELRLGEIAPQLVYRFIEQTMQTGPSVSLKC-SAAGNP 467

Query: 137 EPNVYWKKNGQTLLFDGDSRM---HLVDGGNLV----IQDARQTDAGRYQCIARNAAGTR 189
            P + W  +G  L    D  +   ++   G+++    I   +  D G Y+CIA + AG  
Sbjct: 468 TPQISWLLDGFPLP-QNDRLLIGQYVTVYGDVISHVNISSVKSEDGGEYECIASSRAG-E 525

Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249
            S  A L I+  PY +     V A  G     +C V G P+  ++W +   G  +P    
Sbjct: 526 ASHSARLNIYGLPY-VRPMSTVSAVAGKQFHIKCPVAGYPIESIVWEKD--GVRLPTNMR 582

Query: 250 KVLDDGSLRLDNV-ILADEGEYSCEAENSVGAVS-ASGYLTVYDPPSINLSPNSVNVESG 307
           + + +GSL +D V   AD+G Y+C A N     S  S  + V  PP I     + ++  G
Sbjct: 583 QRVANGSLFIDTVQRAADQGTYTCTARNKHNFTSQRSVEVRVLVPPKITPFSFARDLNVG 642

Query: 308 NVARFTC-TATGRPEPTMFW 326
           +     C   TG    T  W
Sbjct: 643 DRTSVQCVVVTGDLPLTFTW 662



 Score = 63.7 bits (148), Expect = 3e-08
 Identities = 65/279 (23%), Positives = 109/279 (39%), Gaps = 26/279 (9%)

Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR- 384
           W  E +  I    M   KYH   +     ++ +N T + D+  T  C   +      V  
Sbjct: 183 WLQEPSFNIYPSTMGDGKYH---MLSSGELMILNIT-REDAERTYRCRTHHRLTQETVVS 238

Query: 385 ---GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG----EA 437
              G+L +T      PP+I       +  +K   V PC A   P P   WY+      E 
Sbjct: 239 SNVGRLQLTEIRSTMPPMINEKVVYMSARLKDTVVIPCVAYGNPTPTNRWYYNRNQREEP 298

Query: 438 LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRA 497
           +  +    V  DG+L+++ + +SD G+Y C AS+  G       L V +P+N ++     
Sbjct: 299 VEDSSGHYVVRDGSLIIQGVQESDGGSYMCTASNSEGSESMEVRLTVSAPLNVHVQ---- 354

Query: 498 ADVSSLPGPPTKPITHNVTD-TSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556
             + ++       +T + +      L W    K G     G ++   SRE +S  +  R 
Sbjct: 355 PSIQTVDLGKAAHLTCSASGFPQAALYWL---KDGQPLRTGARIRAVSRERISVMSVARE 411

Query: 557 SRG-WVVIARRVHQTHYVVKSL-----IPGITYMFIVRT 589
            RG +    R  ++    +  L      P + Y FI +T
Sbjct: 412 DRGMYQCFVRNEYEMAQGIAELRLGEIAPQLVYRFIEQT 450



 Score = 59.3 bits (137), Expect = 6e-07
 Identities = 56/226 (24%), Positives = 93/226 (41%), Gaps = 12/226 (5%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
           AP ++ + ++ T+      +L C A G+P+P I W   G  +  +    I     ++   
Sbjct: 439 APQLVYRFIEQTMQTGPSVSLKCSAAGNPTPQISWLLDGFPLPQNDRLLIGQYVTVYGDV 498

Query: 71  ATHGRVHS----DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTV 125
            +H  + S    D G Y C A++  G A S +A L++  L     + P S  SA  G   
Sbjct: 499 ISHVNISSVKSEDGGEYECIASSRAGEA-SHSARLNIYGLP---YVRPMSTVSAVAGKQF 554

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
            ++C P  G P  ++ W+K+G  L    + R  + +G   +    R  D G Y C ARN 
Sbjct: 555 HIKC-PVAGYPIESIVWEKDGVRL--PTNMRQRVANGSLFIDTVQRAADQGTYTCTARNK 611

Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231
                     +++ + P +           G   + QC V    LP
Sbjct: 612 HNFTSQRSVEVRVLVPPKITPFSFARDLNVGDRTSVQCVVVTGDLP 657



 Score = 36.3 bits (80), Expect = 5.1
 Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 6/91 (6%)

Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW-SVEGNRTIIFPGMSRDKYHATAVF 350
           P  ++  P+ V   + N  R  CT  G P PT+ W + +G      PG+     + T  F
Sbjct: 25  PSFVSEPPSRVEFTNVNGGRVDCTVRGNPAPTVDWLAADGGSITSIPGIRHVLGNGTIHF 84

Query: 351 DGVTVLTINDTDKNDSRNTIV-CSAVNYAGS 380
            G       +  + D    I  CSAVN  G+
Sbjct: 85  PGFEA----EVFRQDVHWAIYKCSAVNSVGA 111


>UniRef50_Q7Q3K8 Cluster: ENSANGP00000009916; n=4;
           Endopterygota|Rep: ENSANGP00000009916 - Anopheles
           gambiae str. PEST
          Length = 1448

 Score =  104 bits (250), Expect = 1e-20
 Identities = 132/531 (24%), Positives = 203/531 (38%), Gaps = 54/531 (10%)

Query: 78  SDAGVYWCEATN-SYGTARSRNAT-LHVAV-LREEFRLEPESKQSAQ-GDTVVLECLPPR 133
           SD G Y C+    +    + +N T  H+ V     F + PE       GD+++L C    
Sbjct: 221 SDQGWYECKVVFLNRPPKQHKNGTWFHLDVHAPPRFSVTPEDIIYVNLGDSIILNCQAD- 279

Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
           G+P P + W K+   +  D  S + +  DG  L I   R  D G Y CIARN  G + S 
Sbjct: 280 GTPTPEILWYKDANPV--DPSSTVGIFNDGTELRISTIRHEDIGDYTCIARNGEG-QVSH 336

Query: 193 IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP-LPDVLWRRSAGGGNMPLG---R 248
            A + I     ++  P +     G  V F C     P    V W R             R
Sbjct: 337 TARVIIAGGAVIMVPPTNQTKLEGEKVQFTCEAKAMPGNVTVRWFREGSPVREVAALETR 396

Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAV-SASGYLTVYDPPSINLSPNSVNVESG 307
           V +  DGSL ++ V   D G+Y+CE  N +G   SAS YL +  P  +  +P    +   
Sbjct: 397 VTIRKDGSLIINPVSADDSGQYTCEVSNGIGEPQSASAYLNIEYPAKVTFTPTIQYLPFR 456

Query: 308 NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
                 C     P P  + +   ++ ++ P  ++D      + +  ++L       +  R
Sbjct: 457 LAGVVQCYIKANP-PLQYVTWTKDKRLLEPYQTKD----IVIMNNGSLLFTRVNQNHQGR 511

Query: 368 NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN-QTLPIKSMAVFPCTAI---C 423
            T  C+  N  G+    G + V     R PP  T  P       +       C A     
Sbjct: 512 YT--CTPYNAQGTQGSSGHMEVLV---RKPPAFTVEPDPLYQRKVGESVEMHCDAQEAEG 566

Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
           T +P I W       +Q +R  + N G + +++L +SD G Y CVAS+     V +  L+
Sbjct: 567 TSKPNIQWQRRDGQPLQKNRVRI-NSGNITIENLRRSDFGYYQCVASNEVATIVSATQLV 625

Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543
           ++                + P  P   ++ + T+ SVTLSW      G      Y +   
Sbjct: 626 IE---------------GTQPHAPYN-LSGSATEFSVTLSWMPGYSGGPDYKQDYTIWYR 669

Query: 544 SRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHG 594
                  +  P    G          T   +  L PG TY F V  +N+ G
Sbjct: 670 EAGVSEWSTIPVTPSG---------STQVTINRLSPGTTYEFQVIGKNALG 711



 Score = 95.5 bits (227), Expect = 8e-18
 Identities = 83/332 (25%), Positives = 138/332 (41%), Gaps = 23/332 (6%)

Query: 164 NLVIQDARQTDAGRYQC----IARNAAGTRESAIATLKIHIKPYLITGPEDVV-AQTGSS 218
           +L + D R++D G Y+C    + R     +      L +H  P     PED++    G S
Sbjct: 212 SLNLTDIRESDQGWYECKVVFLNRPPKQHKNGTWFHLDVHAPPRFSVTPEDIIYVNLGDS 271

Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENS 277
           +   C+  G P P++LW + A   + P   V + +DG+ LR+  +   D G+Y+C A N 
Sbjct: 272 IILNCQADGTPTPEILWYKDANPVD-PSSTVGIFNDGTELRISTIRHEDIGDYTCIARNG 330

Query: 278 VGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP-EPTMFWSVEGNRTIIF 336
            G VS +  + +     I + P +     G   +FTC A   P   T+ W  EG+     
Sbjct: 331 EGQVSHTARVIIAGGAVIMVPPTNQTKLEGEKVQFTCEAKAMPGNVTVRWFREGSPVREV 390

Query: 337 PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGS-SFVRGKLTVTSDDDR 395
             +   +   T   DG   L IN    +DS     C   N  G        L +      
Sbjct: 391 AAL---ETRVTIRKDG--SLIINPVSADDS-GQYTCEVSNGIGEPQSASAYLNI-----E 439

Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN---VTNDGTL 452
            P  +T  P+ Q LP +   V  C     P      + + + L++ ++     + N+G+L
Sbjct: 440 YPAKVTFTPTIQYLPFRLAGVVQCYIKANPPLQYVTWTKDKRLLEPYQTKDIVIMNNGSL 499

Query: 453 VLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
           +   ++++  G YTC   +  G    SG + V
Sbjct: 500 LFTRVNQNHQGRYTCTPYNAQGTQGSSGHMEV 531



 Score = 81.8 bits (193), Expect = 1e-13
 Identities = 78/306 (25%), Positives = 124/306 (40%), Gaps = 15/306 (4%)

Query: 31  LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
           LNC+A G+P+P I WYK    V   +   I   G    LR +  R H D G Y C A N 
Sbjct: 274 LNCQADGTPTPEILWYKDANPVDPSSTVGIFNDG--TELRISTIR-HEDIGDYTCIARNG 330

Query: 91  YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL- 149
            G   S  A + +A       + P ++   +G+ V   C          V W + G  + 
Sbjct: 331 EGQV-SHTARVIIAG-GAVIMVPPTNQTKLEGEKVQFTCEAKAMPGNVTVRWFREGSPVR 388

Query: 150 -LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208
            +   ++R+ +   G+L+I      D+G+Y C   N  G  +SA A L I     +   P
Sbjct: 389 EVAALETRVTIRKDGSLIINPVSADDSGQYTCEVSNGIGEPQSASAYLNIEYPAKVTFTP 448

Query: 209 EDVVAQTGSSVTFQCRV-GGDPLPDVLWRRSAG-GGNMPLGRVKVLDDGSLRLDNVILAD 266
                    +   QC +    PL  V W +            + ++++GSL    V    
Sbjct: 449 TIQYLPFRLAGVVQCYIKANPPLQYVTWTKDKRLLEPYQTKDIVIMNNGSLLFTRVNQNH 508

Query: 267 EGEYSCEAENSVGAVSASGYLTVY--DPPSINLSPNSV-NVESGNVARFTC---TATGRP 320
           +G Y+C   N+ G   +SG++ V    PP+  + P+ +   + G      C    A G  
Sbjct: 509 QGRYTCTPYNAQGTQGSSGHMEVLVRKPPAFTVEPDPLYQRKVGESVEMHCDAQEAEGTS 568

Query: 321 EPTMFW 326
           +P + W
Sbjct: 569 KPNIQW 574



 Score = 58.0 bits (134), Expect = 1e-06
 Identities = 65/244 (26%), Positives = 106/244 (43%), Gaps = 29/244 (11%)

Query: 60  ILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESK- 117
           I+  G L F R          G Y C   N+ GT  S +  + V V +   F +EP+   
Sbjct: 493 IMNNGSLLFTRVNQNH----QGRYTCTPYNAQGTQGS-SGHMEVLVRKPPAFTVEPDPLY 547

Query: 118 QSAQGDTVVLEC--LPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTD 174
           Q   G++V + C      G+ +PN+ W +++GQ L     +R+  ++ GN+ I++ R++D
Sbjct: 548 QRKVGESVEMHCDAQEAEGTSKPNIQWQRRDGQPLQ---KNRVR-INSGNITIENLRRSD 603

Query: 175 AGRYQCIARNAAGTRESA----IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPL 230
            G YQC+A N   T  SA    I   + H  PY ++G     + T  SVT     G    
Sbjct: 604 FGYYQCVASNEVATIVSATQLVIEGTQPH-APYNLSG-----SATEFSVTLSWMPGYSGG 657

Query: 231 PD-----VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASG 285
           PD      +W R AG        V       + ++ +      E+    +N++G    S 
Sbjct: 658 PDYKQDYTIWYREAGVSEWSTIPVTPSGSTQVTINRLSPGTTYEFQVIGKNALGDGMMSK 717

Query: 286 YLTV 289
            +T+
Sbjct: 718 VITI 721


>UniRef50_A7TCD9 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 303

 Score =  104 bits (250), Expect = 1e-20
 Identities = 78/219 (35%), Positives = 105/219 (47%), Gaps = 22/219 (10%)

Query: 20  DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
           ++T     P TL C+A G P P +RW KGG  +VS  H  I+  G LF  +AT G    D
Sbjct: 97  NLTAFEKAPVTLTCKATGLPLPTVRWIKGGRQLVSKGH-EIVAGGRLFLGKATLG----D 151

Query: 80  AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ--SAQGDTVVLECLPPRGSPE 137
           +G Y C AT+  G   S  + L + VLR +       K   +  G+TV L C    G P 
Sbjct: 152 SGEYECTATSPLGYV-SAKSNLEIKVLRRDKISTDLGKNVTTLSGNTVSLLC-NATGVPS 209

Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
           P + W K+G+TL     +  H V    L +     +D+G YQC ARN  G  ++      
Sbjct: 210 PKLSWYKDGETL-----NISHAV----LTLPTLSPSDSGLYQCEARNLKGIDDADSYLTN 260

Query: 198 IHIKPYLITG-PEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
           I    Y++TG   DVV    S+V   C V G PLP + W
Sbjct: 261 I---AYIVTGIGSDVVTLLSSNVEVTCPVRGFPLPSITW 296



 Score = 91.9 bits (218), Expect = 1e-16
 Identities = 91/311 (29%), Positives = 129/311 (41%), Gaps = 28/311 (9%)

Query: 30  TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH-SDAGVYWCEAT 88
           T+NC   G P P++ W    V          L A  +   R T  ++  SD+GVY C A 
Sbjct: 8   TINCPTEGLPRPSVTW---SVTRTQAPGVEGLQAVPIVTSRLTVAKLQLSDSGVYTCTAR 64

Query: 89  NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT------VVLECLPPRGSPEPNVYW 142
           N  G     + T  V V   +  LEP S       T      V L C    G P P V W
Sbjct: 65  NLKGNDTMTSVTSIVPVEALK-NLEPVSVLIGANLTAFEKAPVTLTC-KATGLPLPTVRW 122

Query: 143 KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI-- 200
            K G+ L+  G     +V GG L +  A   D+G Y+C A +  G   SA + L+I +  
Sbjct: 123 IKGGRQLVSKGHE---IVAGGRLFLGKATLGDSGEYECTATSPLGY-VSAKSNLEIKVLR 178

Query: 201 KPYLITG-PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL 259
           +  + T   ++V   +G++V+  C   G P P + W +         G    +    L L
Sbjct: 179 RDKISTDLGKNVTTLSGNTVSLLCNATGVPSPKLSWYKD--------GETLNISHAVLTL 230

Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGR 319
             +  +D G Y CEA N  G   A  YLT        +  + V + S NV   TC   G 
Sbjct: 231 PTLSPSDSGLYQCEARNLKGIDDADSYLTNIAYIVTGIGSDVVTLLSSNV-EVTCPVRGF 289

Query: 320 PEPTMFWSVEG 330
           P P++ W  +G
Sbjct: 290 PLPSITWLKDG 300



 Score = 87.8 bits (208), Expect = 2e-15
 Identities = 66/220 (30%), Positives = 98/220 (44%), Gaps = 16/220 (7%)

Query: 122 GDTVVLECLPPRGSPEPNVYWK-KNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
           G  + + C P  G P P+V W     Q    +G   + +V    L +   + +D+G Y C
Sbjct: 4   GSALTINC-PTEGLPRPSVTWSVTRTQAPGVEGLQAVPIVTS-RLTVAKLQLSDSGVYTC 61

Query: 181 IARNAAG--TRESAIATLKI----HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL 234
            ARN  G  T  S  + + +    +++P  +    ++ A   + VT  C+  G PLP V 
Sbjct: 62  TARNLKGNDTMTSVTSIVPVEALKNLEPVSVLIGANLTAFEKAPVTLTCKATGLPLPTVR 121

Query: 235 WRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV----Y 290
           W +  GG  +     +++  G L L    L D GEY C A + +G VSA   L +     
Sbjct: 122 WIK--GGRQLVSKGHEIVAGGRLFLGKATLGDSGEYECTATSPLGYVSAKSNLEIKVLRR 179

Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
           D  S +L  N V   SGN     C ATG P P + W  +G
Sbjct: 180 DKISTDLGKN-VTTLSGNTVSLLCNATGVPSPKLSWYKDG 218



 Score = 74.5 bits (175), Expect = 2e-11
 Identities = 75/268 (27%), Positives = 114/268 (42%), Gaps = 30/268 (11%)

Query: 216 GSSVTFQCRVGGDPLPDVLWR--RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCE 273
           GS++T  C   G P P V W   R+   G   L  V ++    L +  + L+D G Y+C 
Sbjct: 4   GSALTINCPTEGLPRPSVTWSVTRTQAPGVEGLQAVPIVTS-RLTVAKLQLSDSGVYTCT 62

Query: 274 AENSVGAVSASGYLTVYDPPSI-NLSPNSVNVESGNVA------RFTCTATGRPEPTMFW 326
           A N  G  + +   ++    ++ NL P SV + +   A        TC ATG P PT+ W
Sbjct: 63  ARNLKGNDTMTSVTSIVPVEALKNLEPVSVLIGANLTAFEKAPVTLTCKATGLPLPTVRW 122

Query: 327 SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
            ++G R ++  G   +      +F G    T+ D+ + +      C+A +  G  +V  K
Sbjct: 123 -IKGGRQLVSKG--HEIVAGGRLFLGKA--TLGDSGEYE------CTATSPLG--YVSAK 169

Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNV 446
             +     R   I T+   N T    +     C A   P P ++WY +GE L  +H    
Sbjct: 170 SNLEIKVLRRDKISTDLGKNVTTLSGNTVSLLCNATGVPSPKLSWYKDGETLNISH---- 225

Query: 447 TNDGTLVLKDLDKSDSGTYTCVASSRHG 474
                L L  L  SDSG Y C A +  G
Sbjct: 226 ---AVLTLPTLSPSDSGLYQCEARNLKG 250



 Score = 46.8 bits (106), Expect = 0.004
 Identities = 51/226 (22%), Positives = 83/226 (36%), Gaps = 11/226 (4%)

Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
           +G+     C   G P P++ WSV   +    PG+  +   A  +    + LT+     +D
Sbjct: 3   AGSALTINCPTEGLPRPSVTWSVTRTQA---PGV--EGLQAVPIV--TSRLTVAKLQLSD 55

Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDD--DRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
           S     C+A N  G+  +    ++   +      P+     +N T   K+     C A  
Sbjct: 56  S-GVYTCTARNLKGNDTMTSVTSIVPVEALKNLEPVSVLIGANLTAFEKAPVTLTCKATG 114

Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
            P P + W   G  L+      V   G L L      DSG Y C A+S  G       L 
Sbjct: 115 LPLPTVRWIKGGRQLVSKGHEIVAG-GRLFLGKATLGDSGEYECTATSPLGYVSAKSNLE 173

Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
           +       I      +V++L G     + +     S  LSW ++ +
Sbjct: 174 IKVLRRDKISTDLGKNVTTLSGNTVSLLCNATGVPSPKLSWYKDGE 219



 Score = 46.8 bits (106), Expect = 0.004
 Identities = 38/130 (29%), Positives = 59/130 (45%), Gaps = 15/130 (11%)

Query: 20  DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
           +VT       +L C A G PSP + WYK G  +  +   ++L    L           SD
Sbjct: 189 NVTTLSGNTVSLLCNATGVPSPKLSWYKDGETL--NISHAVLTLPTLS---------PSD 237

Query: 80  AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
           +G+Y CEA N  G   + +   ++A +      +  +  S+    V + C P RG P P+
Sbjct: 238 SGLYQCEARNLKGIDDADSYLTNIAYIVTGIGSDVVTLLSSN---VEVTC-PVRGFPLPS 293

Query: 140 VYWKKNGQTL 149
           + W K+GQ L
Sbjct: 294 ITWLKDGQPL 303


>UniRef50_UPI00015B5ECA Cluster: PREDICTED: similar to rCG56583;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           rCG56583 - Nasonia vitripennis
          Length = 1130

 Score =  103 bits (248), Expect = 2e-20
 Identities = 96/347 (27%), Positives = 141/347 (40%), Gaps = 27/347 (7%)

Query: 71  ATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
           AT    +S    Y C A  SYG + RS    +  A L   FR  PE     +G+   L C
Sbjct: 115 ATVSSRNSQRNEYRCVARTSYGASLRSAPTNILYAELAHTFRESPEDSTVREGEVARLSC 174

Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMH-LVDGGNLVIQDARQTDAGRYQCIARN---- 184
           L       PN+ W  +G+ +  D +   +  +  G L I+  + +DAG Y+C+A N    
Sbjct: 175 LIDSVPFPPNITWLHDGELVPTDHNKTKYAFIPPGVLYIRATKLSDAGSYRCVAANDFIN 234

Query: 185 -AAGTRESAIATLKIHIKPYLITG----PEDVVAQT---GSSVTFQCRVGGDPLPDVLWR 236
               ++E+ +  +  H      +     P+   + T   GS +   C   G P P   W 
Sbjct: 235 ATKKSKEAKLTVISRHESKESSSSVSLFPQTSYSHTPLIGSHLKLACAASGYPPPKTSWT 294

Query: 237 RSAGGGNMPLGRVKVLDDGS-----LRLDNVILADEGEYSCEAENSVGAVSASGYLTV-- 289
             A   +    + + L + S     L L N+   D G Y C   N     +    LTV  
Sbjct: 295 FVAQYADTETAKHRALLNSSSGLAVLELKNITTTDAGTYVCSVNNITSNATEIQNLTVEV 354

Query: 290 YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
           Y PP+    P +    +G  ARF C A G P P ++W ++    I   G  R  Y     
Sbjct: 355 YVPPTFVKKPTNQACPNGRTARFECQARGFPTPRIYW-LKNAADITING-RRTVYEKE-- 410

Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP 396
           F+ V  L I+ T  +DS     C AVN AG     G+L V +  + P
Sbjct: 411 FNKVE-LAISATVPSDS-GIYQCVAVNAAGEVSAAGRLQVNTSRNSP 455



 Score =  101 bits (242), Expect = 1e-19
 Identities = 156/675 (23%), Positives = 252/675 (37%), Gaps = 86/675 (12%)

Query: 163 GNLVIQDARQTDAGRYQCIARNAAGT--RESAIATLKIHIKPYLITGPEDVVAQTGSSVT 220
           GN  +  +R +    Y+C+AR + G   R +    L   +       PED   + G    
Sbjct: 113 GNATVS-SRNSQRNEYRCVARTSYGASLRSAPTNILYAELAHTFRESPEDSTVREGEVAR 171

Query: 221 FQCRVGGDPLP-DVLWRRSAGGGNMPLGRVKV----LDDGSLRLDNVILADEGEYSCEAE 275
             C +   P P ++ W     G  +P    K     +  G L +    L+D G Y C A 
Sbjct: 172 LSCLIDSVPFPPNITWLHD--GELVPTDHNKTKYAFIPPGVLYIRATKLSDAGSYRCVAA 229

Query: 276 NS-VGAVSAS--GYLTVYD-------PPSINLSPNSVNVES---GNVARFTCTATGRPEP 322
           N  + A   S    LTV           S++L P +    +   G+  +  C A+G P P
Sbjct: 230 NDFINATKKSKEAKLTVISRHESKESSSSVSLFPQTSYSHTPLIGSHLKLACAASGYPPP 289

Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
              W+             R   ++++   G+ VL + +    D+  T VCS  N   ++ 
Sbjct: 290 KTSWTFVAQYADTETAKHRALLNSSS---GLAVLELKNITTTDA-GTYVCSVNNITSNAT 345

Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH 442
               LTV   +   PP     P+NQ  P    A F C A   P P I W      +  N 
Sbjct: 346 EIQNLTV---EVYVPPTFVKKPTNQACPNGRTARFECQARGFPTPRIYWLKNAADITING 402

Query: 443 RRNV----TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAA 498
           RR V     N   L +     SDSG Y CVA +  G+   +G L V++  N         
Sbjct: 403 RRTVYEKEFNKVELAISATVPSDSGIYQCVAVNAAGEVSAAGRLQVNTSRNS-------- 454

Query: 499 DVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558
                P  PT       +   + +SW     +  ++I  Y V    R    G        
Sbjct: 455 -----PAAPTSLKCEARSPVKIFISWEPPKFLPFTNI-AYTVHY--RPVEGGKEEVSPEP 506

Query: 559 GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGT 618
           G             V K L P   Y F VR  N+H   GPS  SD++T   +        
Sbjct: 507 GNTTSVE-------VTKLLEPFTNYTFYVRLWNNH---GPSDQSDTITCSTNE------- 549

Query: 619 GVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEY 678
           GV  +               I    I+S  + + W+ L     +G+   ++    +    
Sbjct: 550 GVPKA------------APKISVDAINSTKLNVTWKPLTKKEAQGIVTEYKLEWRLFQHP 597

Query: 679 EMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPI-N 737
            ++       V  + +T +     Y+  ++   K+     +NS+       +P    +  
Sbjct: 598 SVRVRTLPATVEQYVLTDMIPGEPYDIRVLARTKQGWPNVNNSQFGWITVTMPQSNDLTQ 657

Query: 738 IEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIM 797
            ++FILN+T + +KW+     ++   I  +N    +       ++V++N T   AT  ++
Sbjct: 658 TQVFILNSTAIQVKWN-----VKAYSILHFNSWKLYCKNEDGVTIVSVNLT-KNATEYLL 711

Query: 798 TNLTSGVSYSVQIAA 812
           TNL S +SYSV++ A
Sbjct: 712 TNLESNISYSVELCA 726



 Score = 96.3 bits (229), Expect = 4e-18
 Identities = 88/314 (28%), Positives = 133/314 (42%), Gaps = 28/314 (8%)

Query: 16  EQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSD---THRSILPAGGLFFLRA 71
           E P D TV   + A L+C     P P  I W   G LV +D   T  + +P G L+ +RA
Sbjct: 157 ESPEDSTVREGEVARLSCLIDSVPFPPNITWLHDGELVPTDHNKTKYAFIPPGVLY-IRA 215

Query: 72  THGRVHSDAGVYWCEATNSY--GTARSRNATLHVAVLREE------FRLEPESKQSAQ-- 121
           T     SDAG Y C A N +   T +S+ A L V    E         L P++  S    
Sbjct: 216 TK---LSDAGSYRCVAANDFINATKKSKEAKLTVISRHESKESSSSVSLFPQTSYSHTPL 272

Query: 122 -GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN----LVIQDARQTDAG 176
            G  + L C    G P P   W    Q    +      L++  +    L +++   TDAG
Sbjct: 273 IGSHLKLACAAS-GYPPPKTSWTFVAQYADTETAKHRALLNSSSGLAVLELKNITTTDAG 331

Query: 177 RYQCIARN-AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
            Y C   N  +   E    T+++++ P  +  P +     G +  F+C+  G P P + W
Sbjct: 332 TYVCSVNNITSNATEIQNLTVEVYVPPTFVKKPTNQACPNGRTARFECQARGFPTPRIYW 391

Query: 236 RRSAGGGNMPLGRV---KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
            ++A    +   R    K  +   L +   + +D G Y C A N+ G VSA+G L V   
Sbjct: 392 LKNAADITINGRRTVYEKEFNKVELAISATVPSDSGIYQCVAVNAAGEVSAAGRLQVNTS 451

Query: 293 PSINLSPNSVNVES 306
            +   +P S+  E+
Sbjct: 452 RNSPAAPTSLKCEA 465



 Score = 44.4 bits (100), Expect = 0.019
 Identities = 32/130 (24%), Positives = 51/130 (39%), Gaps = 2/130 (1%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P  +++P +      + A   C+A G P+P I W K    +  +  R++          A
Sbjct: 358 PTFVKKPTNQACPNGRTARFECQARGFPTPRIYWLKNAADITINGRRTVYEKEFNKVELA 417

Query: 72  THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT-VVLECL 130
               V SD+G+Y C A N+ G   S    L V   R         K  A+    + +   
Sbjct: 418 ISATVPSDSGIYQCVAVNAAGEV-SAAGRLQVNTSRNSPAAPTSLKCEARSPVKIFISWE 476

Query: 131 PPRGSPEPNV 140
           PP+  P  N+
Sbjct: 477 PPKFLPFTNI 486


>UniRef50_Q7SY58 Cluster: Muscle, skeletal, receptor tyrosine
           kinase; n=2; Danio rerio|Rep: Muscle, skeletal, receptor
           tyrosine kinase - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 351

 Score =  103 bits (247), Expect = 3e-20
 Identities = 61/203 (30%), Positives = 98/203 (48%), Gaps = 5/203 (2%)

Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIA 194
           P+ ++ W +N   + +  DSR  + + G  L+I + + +D+G Y CIA N  G  +S  A
Sbjct: 53  PQADIIWTRNNYPIRYY-DSRYVIQENGQMLIIPNVKDSDSGEYCCIANNGVGEAKSCGA 111

Query: 195 TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254
            L++ +KP +   P ++     S     C   G P P++ W +          R+ +L+ 
Sbjct: 112 -LQLKMKPQIKRHPTNMTLILESKAVLPCLSLGYPKPEISWIKEDDLIKAN-NRIAILES 169

Query: 255 GSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313
           GSL++ N+   D G+Y C A NS G A S    + V  P  I   P    V+ G+     
Sbjct: 170 GSLKITNIKKEDAGQYRCVARNSFGIAFSRPVTIEVQAPAKILKVPKEKRVQIGSEVTLE 229

Query: 314 CTATGRPEPTMFWSVEGNRTIIF 336
           C ATG P P++ W   GN  I++
Sbjct: 230 CNATGNPIPSITWLENGNTVILY 252



 Score = 95.1 bits (226), Expect = 1e-17
 Identities = 57/207 (27%), Positives = 97/207 (46%), Gaps = 7/207 (3%)

Query: 29  ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
           AT  C     P   I W +    +     R ++   G   +        SD+G Y C A 
Sbjct: 43  ATFICEVDSYPQADIIWTRNNYPIRYYDSRYVIQENGQMLI--IPNVKDSDSGEYCCIAN 100

Query: 89  NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
           N  G A+S  A L +  ++ + +  P +         VL CL   G P+P + W K    
Sbjct: 101 NGVGEAKSCGA-LQLK-MKPQIKRHPTNMTLILESKAVLPCLS-LGYPKPEISWIKEDD- 156

Query: 149 LLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208
            L   ++R+ +++ G+L I + ++ DAG+Y+C+ARN+ G   S   T+++     ++  P
Sbjct: 157 -LIKANNRIAILESGSLKITNIKKEDAGQYRCVARNSFGIAFSRPVTIEVQAPAKILKVP 215

Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLW 235
           ++   Q GS VT +C   G+P+P + W
Sbjct: 216 KEKRVQIGSEVTLECNATGNPIPSITW 242



 Score = 75.4 bits (177), Expect = 9e-12
 Identities = 47/139 (33%), Positives = 72/139 (51%), Gaps = 6/139 (4%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P I   P ++T+     A L C + G P P I W K   L+ ++   +IL +G    L+ 
Sbjct: 118 PQIKRHPTNMTLILESKAVLPCLSLGYPKPEISWIKEDDLIKANNRIAILESGS---LKI 174

Query: 72  THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
           T+ +   DAG Y C A NS+G A SR  T+ V    +  ++ P+ K+   G  V LEC  
Sbjct: 175 TNIK-KEDAGQYRCVARNSFGIAFSRPVTIEVQAPAKILKV-PKEKRVQIGSEVTLEC-N 231

Query: 132 PRGSPEPNVYWKKNGQTLL 150
             G+P P++ W +NG T++
Sbjct: 232 ATGNPIPSITWLENGNTVI 250



 Score = 72.1 bits (169), Expect = 8e-11
 Identities = 65/239 (27%), Positives = 99/239 (41%), Gaps = 15/239 (6%)

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLD 260
           P + T  E V +    + TF C V   P  D++W R+         R  + ++G  L + 
Sbjct: 26  PRITTLLETVDSSLDHNATFICEVDSYPQADIIWTRNNYPIRYYDSRYVIQENGQMLIIP 85

Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
           NV  +D GEY C A N VG   + G L +   P I   P ++ +   + A   C + G P
Sbjct: 86  NVKDSDSGEYCCIANNGVGEAKSCGALQLKMKPQIKRHPTNMTLILESKAVLPCLSLGYP 145

Query: 321 EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGS 380
           +P + W  E +   +    +R      A+ +  + L I +  K D+     C A N  G 
Sbjct: 146 KPEISWIKEDD---LIKANNR-----IAILESGS-LKITNIKKEDA-GQYRCVARNSFGI 195

Query: 381 SFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI 439
           +F R    VT +   P  I+   P  + + I S     C A   P P I W   G  +I
Sbjct: 196 AFSR---PVTIEVQAPAKIL-KVPKEKRVQIGSEVTLECNATGNPIPSITWLENGNTVI 250



 Score = 64.9 bits (151), Expect = 1e-08
 Identities = 48/182 (26%), Positives = 81/182 (44%), Gaps = 13/182 (7%)

Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
           P I     +V+    + A F C     P+  + W+        +P    D  +   + + 
Sbjct: 26  PRITTLLETVDSSLDHNATFICEVDSYPQADIIWTRNN-----YPIRYYDSRYV--IQEN 78

Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
             +L I +   +DS     C A N  G +   G L +     +  P I   P+N TL ++
Sbjct: 79  GQMLIIPNVKDSDS-GEYCCIANNGVGEAKSCGALQL-----KMKPQIKRHPTNMTLILE 132

Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
           S AV PC ++  P+P I+W  E + +  N+R  +   G+L + ++ K D+G Y CVA + 
Sbjct: 133 SKAVLPCLSLGYPKPEISWIKEDDLIKANNRIAILESGSLKITNIKKEDAGQYRCVARNS 192

Query: 473 HG 474
            G
Sbjct: 193 FG 194


>UniRef50_A0JM54 Cluster: LOC100036605 protein; n=1; Xenopus
           tropicalis|Rep: LOC100036605 protein - Xenopus
           tropicalis (Western clawed frog) (Silurana tropicalis)
          Length = 1423

 Score =  103 bits (246), Expect = 4e-20
 Identities = 158/660 (23%), Positives = 257/660 (38%), Gaps = 69/660 (10%)

Query: 79  DAGVYWCEAT---NSYGTARSRNAT-LHVAVLRE-EFRLEPESKQSAQ-GDTVVLECLPP 132
           D G Y C        +G    +N T +H+ V     FR  P +    + GDT+ L C+  
Sbjct: 102 DQGWYECRVLFLDRHHGEEDFQNGTWVHLTVNSPPSFRETPPTYVEVRVGDTLTLTCVA- 160

Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
            G+P+P V WK++G TL   GD        G+L I    + +AG Y C A +  G     
Sbjct: 161 YGNPQPVVTWKRDGVTLE-SGDKVQ--ASNGSLSIVGVERGNAGVYTCHAFSDEGEVTHT 217

Query: 193 IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-----G 247
              L +   P ++  PE+            C+    P  ++ +    G  N+ L      
Sbjct: 218 SRVL-VQGPPIIVVPPENTTVNVSQDAFLTCQAEAYPA-NLTYTWFQGSNNVFLLNRLQP 275

Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSPNSVNVES 306
           RV++L DGS  +  V   D G+Y+C   N +  + SAS YLTV  P  +   P    +  
Sbjct: 276 RVRILVDGSFLIQRVTPEDAGKYTCIPSNGMWKSPSASAYLTVLHPAYVTSMPAETYLPI 335

Query: 307 GNVARFTCTATGRPEPTMF-WSVEGNRTIIFPGMSRDKYHATAVF-DGVTVLTINDTDKN 364
           G      C     P   +  W+ +G+       +  DKY    V  DG  V+    T  +
Sbjct: 336 GMRGVIKCPVRANPPLLLVNWTKDGH------ALELDKYPGWYVDEDGSLVIA---TGND 386

Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP-IKSMAVFPCTAIC 423
           D+     C+  N  G+  V     V   +   PP   + PS +    +    V PC+A+ 
Sbjct: 387 DALGIYTCTPYNSYGTGGVSLPTEVILKE---PPSFIDVPSEEYFQDVGRELVIPCSAVG 443

Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
            P P+I W   G  L       +  + +LV + L K + G + C A++         A+ 
Sbjct: 444 DPPPLIRWSKLG--LPGKSAAQMDANSSLVFRPLTKEEHGIWECSATNHVATISARTAIY 501

Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543
           V   +  + H     ++S+L              +SV +SW      G       +  V+
Sbjct: 502 V---LGTSPH--AVTNISALS-----------LVSSVNVSWEP----GFDGGYFQRFSVW 541

Query: 544 SRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
               +      R    W+ ++  V  TH +V +L     Y F + ++N     G  P S+
Sbjct: 542 YAPLV--KRLTRGHHDWISLSAAVGATHLLVGNLQADTAYQFSILSQNK---LGTGPFSE 596

Query: 604 SVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMW--EILNFYYL 661
            VT    +  +        ++E  +++     +   E     S+ + L W   + +   L
Sbjct: 597 IVTATPLNFPVTTVPPPVPTSEPSDSLSPPRYLSANET----SEGVFLQWLPPLRSSLPL 652

Query: 662 EGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNS 721
            G  + FR  D    E   ++I  S   +   +  L K T YEF L+ F   +  +PSNS
Sbjct: 653 RGYGLEFR-RDEGAWELLDESIPESQ--TELVVRKLVKDTMYEFRLVAFAGDYISEPSNS 709



 Score = 85.0 bits (201), Expect = 1e-14
 Identities = 83/329 (25%), Positives = 134/329 (40%), Gaps = 21/329 (6%)

Query: 156 RMHLVDGGNLVIQDARQTDAGRYQC---IARNAAGTRESAIAT---LKIHIKP-YLITGP 208
           R  + +G +L I+  R  D G Y+C         G  +    T   L ++  P +  T P
Sbjct: 84  RTRIEEGASLHIESLRSEDQGWYECRVLFLDRHHGEEDFQNGTWVHLTVNSPPSFRETPP 143

Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268
             V  + G ++T  C   G+P P V W+R   G  +  G      +GSL +  V   + G
Sbjct: 144 TYVEVRVGDTLTLTCVAYGNPQPVVTWKRD--GVTLESGDKVQASNGSLSIVGVERGNAG 201

Query: 269 EYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328
            Y+C A +  G V+ +  + V  PP I + P +  V     A  TC A   P    +   
Sbjct: 202 VYTCHAFSDEGEVTHTSRVLVQGPPIIVVPPENTTVNVSQDAFLTCQAEAYPANLTYTWF 261

Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT 388
           +G+  +    ++R +     + DG + L    T ++  + T + S   +   S     LT
Sbjct: 262 QGSNNVFL--LNRLQPRVRILVDG-SFLIQRVTPEDAGKYTCIPSNGMWKSPS-ASAYLT 317

Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA-WYFEGEALIQNHRRN-- 445
           V       P  +T+ P+   LPI    V  C     P  ++  W  +G AL  +      
Sbjct: 318 VLH-----PAYVTSMPAETYLPIGMRGVIKCPVRANPPLLLVNWTKDGHALELDKYPGWY 372

Query: 446 VTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
           V  DG+LV+   +    G YTC   + +G
Sbjct: 373 VDEDGSLVIATGNDDALGIYTCTPYNSYG 401



 Score = 77.0 bits (181), Expect = 3e-12
 Identities = 84/321 (26%), Positives = 122/321 (38%), Gaps = 16/321 (4%)

Query: 18  PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
           P  V V      TL C A G+P P + W + GV + S   +     G L  +    G   
Sbjct: 143 PTYVEVRVGDTLTLTCVAYGNPQPVVTWKRDGVTLESG-DKVQASNGSLSIVGVERG--- 198

Query: 78  SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
            +AGVY C A +  G     +  L          + PE+          L C        
Sbjct: 199 -NAGVYTCHAFSDEGEVTHTSRVLVQG--PPIIVVPPENTTVNVSQDAFLTCQAEAYPAN 255

Query: 138 PNVYW--KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195
               W    N   LL     R+ ++  G+ +IQ     DAG+Y CI  N      SA A 
Sbjct: 256 LTYTWFQGSNNVFLLNRLQPRVRILVDGSFLIQRVTPEDAGKYTCIPSNGMWKSPSASAY 315

Query: 196 LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK---VL 252
           L +    Y+ + P +     G     +C V  +P P +L   +  G  + L +     V 
Sbjct: 316 LTVLHPAYVTSMPAETYLPIGMRGVIKCPVRANP-PLLLVNWTKDGHALELDKYPGWYVD 374

Query: 253 DDGSLRLDNVILADEGEYSCEAENS--VGAVSASGYLTVYDPPS-INLSPNSVNVESGNV 309
           +DGSL +        G Y+C   NS   G VS    + + +PPS I++       + G  
Sbjct: 375 EDGSLVIATGNDDALGIYTCTPYNSYGTGGVSLPTEVILKEPPSFIDVPSEEYFQDVGRE 434

Query: 310 ARFTCTATGRPEPTMFWSVEG 330
               C+A G P P + WS  G
Sbjct: 435 LVIPCSAVGDPPPLIRWSKLG 455



 Score = 73.7 bits (173), Expect = 3e-11
 Identities = 81/310 (26%), Positives = 128/310 (41%), Gaps = 21/310 (6%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSP-AIRWYKGG--VLVVS--DTHRSILPAGGL 66
           P I+  P + TV   Q A L C+A   P+     W++G   V +++       IL  G  
Sbjct: 226 PIIVVPPENTTVNVSQDAFLTCQAEAYPANLTYTWFQGSNNVFLLNRLQPRVRILVDGSF 285

Query: 67  FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTV 125
              R T      DAG Y C  +N  G  +S +A+ ++ VL   +    P       G   
Sbjct: 286 LIQRVTP----EDAGKYTCIPSN--GMWKSPSASAYLTVLHPAYVTSMPAETYLPIGMRG 339

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
           V++C      P   V W K+G  L  D     ++ + G+LVI        G Y C   N+
Sbjct: 340 VIKCPVRANPPLLLVNWTKDGHALELDKYPGWYVDEDGSLVIATGNDDALGIYTCTPYNS 399

Query: 186 AGTRESAIATLKIHIKP--YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
            GT   ++ T  I  +P  ++    E+     G  +   C   GDP P + W +    G 
Sbjct: 400 YGTGGVSLPTEVILKEPPSFIDVPSEEYFQDVGRELVIPCSAVGDPPPLIRWSKLGLPGK 459

Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSA--SGYLTVYDPPSI-NLSPN 300
                 ++  + SL    +   + G + C A N V  +SA  + Y+    P ++ N+S  
Sbjct: 460 ---SAAQMDANSSLVFRPLTKEEHGIWECSATNHVATISARTAIYVLGTSPHAVTNISAL 516

Query: 301 SVNVESGNVA 310
           S+ V S NV+
Sbjct: 517 SL-VSSVNVS 525



 Score = 68.1 bits (159), Expect = 1e-09
 Identities = 62/239 (25%), Positives = 104/239 (43%), Gaps = 29/239 (12%)

Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEA---ENSVGAVSASG----YLTVYDPPSINLS 298
           LGR ++ +  SL ++++   D+G Y C     +   G          +LTV  PPS   +
Sbjct: 82  LGRTRIEEGASLHIESLRSEDQGWYECRVLFLDRHHGEEDFQNGTWVHLTVNSPPSFRET 141

Query: 299 PNS-VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
           P + V V  G+    TC A G P+P + W  +G         S DK  A+   +G   L+
Sbjct: 142 PPTYVEVRVGDTLTLTCVAYGNPQPVVTWKRDGVTL-----ESGDKVQAS---NG--SLS 191

Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
           I   ++ ++     C A +  G      ++ V     + PPII   P N T+ +   A  
Sbjct: 192 IVGVERGNA-GVYTCHAFSDEGEVTHTSRVLV-----QGPPIIVVPPENTTVNVSQDAFL 245

Query: 418 PCTAICTPEPIIAWYFEG--EALIQNH---RRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
            C A   P  +   +F+G     + N    R  +  DG+ +++ +   D+G YTC+ S+
Sbjct: 246 TCQAEAYPANLTYTWFQGSNNVFLLNRLQPRVRILVDGSFLIQRVTPEDAGKYTCIPSN 304


>UniRef50_Q6UXZ4 Cluster: Netrin receptor UNC5D precursor; n=44;
           Euteleostomi|Rep: Netrin receptor UNC5D precursor - Homo
           sapiens (Human)
          Length = 953

 Score =  103 bits (246), Expect = 4e-20
 Identities = 63/203 (31%), Positives = 101/203 (49%), Gaps = 13/203 (6%)

Query: 9   GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRS---ILPAGG 65
           G  P+ IE+P D  + +  P  L C+A   P+  I +   G  V  + H S   +  + G
Sbjct: 51  GTLPHFIEEPDDAYIIKSNPIALRCKA--RPAMQIFFKCNGEWVHQNEHVSEETLDESSG 108

Query: 66  L----FFLRATHGRVHSDAGV--YWCE--ATNSYGTARSRNATLHVAVLREEFRLEPESK 117
           L     F+  T  +V    G   YWC+  A +  GT++SR A++ +A LR+ F  +P+ +
Sbjct: 109 LKVREVFINVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGR 168

Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR 177
           +      +VL C PP G P   V W KN + +  + D  +      NL+I+ AR +D+G 
Sbjct: 169 EVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGN 228

Query: 178 YQCIARNAAGTRESAIATLKIHI 200
           Y C+A N    R S  AT+ +++
Sbjct: 229 YTCMAANIVAKRRSLSATVVVYV 251



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 20/71 (28%), Positives = 32/71 (45%), Gaps = 3/71 (4%)

Query: 404 PSNQTLPIKSMAVFPCTAI-CTPEPIIAWYFEGEALIQNHRRNVTN--DGTLVLKDLDKS 460
           P  + +PI+ M V  C      P   + W    E +      N+    D  L+++    S
Sbjct: 165 PQGREVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLS 224

Query: 461 DSGTYTCVASS 471
           DSG YTC+A++
Sbjct: 225 DSGNYTCMAAN 235


>UniRef50_Q6PDN3 Cluster: Myosin light chain kinase, smooth muscle;
           n=34; Euteleostomi|Rep: Myosin light chain kinase,
           smooth muscle - Mus musculus (Mouse)
          Length = 1941

 Score =  103 bits (246), Expect = 4e-20
 Identities = 100/353 (28%), Positives = 133/353 (37%), Gaps = 42/353 (11%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-DTHRSILPAGGLFFLR 70
           P    QP    V   Q     C   G P P + W+  G+ V   +    +   G    L 
Sbjct: 402 PRFESQPQSQEVTEGQTVKFICEVSGIPKPDVGWFLEGIPVRRREGITEVYEDGVSHHLC 461

Query: 71  ATHGRVHSDAGVYWCEATNSYGTARSRNATL----HVAVLREEFRLEPESKQSAQGDTVV 126
               R   D+  Y C A+NS G      + L    ++A     F    +     +G   V
Sbjct: 462 LLRARTR-DSRKYSCTASNSLGQVSCSWSLLVDRPNLAQTAPSFSSVLKDSVVIEGQDFV 520

Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARN 184
           L C   +G+P P V W  NGQ + F       + + G   L IQDA   D G Y C+A N
Sbjct: 521 LRC-SVQGTPAPRVTWLLNGQPIQFAHS----ICEAGVAELHIQDALPEDRGTYTCLAEN 575

Query: 185 AAGTRESAIATLKIH-------------------IKPYLITGPEDVVAQTGSSVTFQCRV 225
           A G + S  AT+ +                    I P  + G  D+    GS VT   +V
Sbjct: 576 AMG-QVSCSATVTVQEKKGEGEREHRLSPARSKPIAPIFLQGLSDLKVMDGSQVTMTVQV 634

Query: 226 GGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVS 282
            G+P P+V+W    G              G   SL +  V   D G Y+CEA NS G V 
Sbjct: 635 SGNPPPEVIWLHD-GNEIQESEDFHFEQKGGWHSLCIQEVFPEDTGTYTCEAWNSAGEVR 693

Query: 283 ASGYLTVYDP-----PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
               LTV +P     P     P SV    G     +C   G P PT+ W  +G
Sbjct: 694 TRAVLTVQEPHDGTQPWFISKPRSVTATLGQSVLISCAIAGDPFPTVHWLRDG 746



 Score = 96.7 bits (230), Expect = 3e-18
 Identities = 104/400 (26%), Positives = 164/400 (41%), Gaps = 47/400 (11%)

Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLF-DGDSRMHLVDG--GNLV 166
           F  +P+S++  +G TV   C    G P+P+V W   G  +   +G + ++  DG   +L 
Sbjct: 404 FESQPQSQEVTEGQTVKFIC-EVSGIPKPDVGWFLEGIPVRRREGITEVY-EDGVSHHLC 461

Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP------EDVVAQTGSSVT 220
           +  AR  D+ +Y C A N+ G + S   +L +       T P      +D V   G    
Sbjct: 462 LLRARTRDSRKYSCTASNSLG-QVSCSWSLLVDRPNLAQTAPSFSSVLKDSVVIEGQDFV 520

Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSV 278
            +C V G P P V W  +  G  +      + + G   L + + +  D G Y+C AEN++
Sbjct: 521 LRCSVQGTPAPRVTWLLN--GQPIQFAH-SICEAGVAELHIQDALPEDRGTYTCLAENAM 577

Query: 279 GAVSASGYLTVYDPPSIN-----LSP--------------NSVNVESGNVARFTCTATGR 319
           G VS S  +TV +          LSP              + + V  G+    T   +G 
Sbjct: 578 GQVSCSATVTVQEKKGEGEREHRLSPARSKPIAPIFLQGLSDLKVMDGSQVTMTVQVSGN 637

Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379
           P P + W  +GN          + +H      G   L I +    D+  T  C A N AG
Sbjct: 638 PPPEVIWLHDGNEI-----QESEDFHFEQK-GGWHSLCIQEVFPEDT-GTYTCEAWNSAG 690

Query: 380 SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI 439
               R  LTV    D   P   + P + T  +    +  C     P P + W  +G AL 
Sbjct: 691 EVRTRAVLTVQEPHDGTQPWFISKPRSVTATLGQSVLISCAIAGDPFPTVHWLRDGRALS 750

Query: 440 QN--HRRNVTNDG--TLVLKDLDKSDSGTYTCVASSRHGK 475
           ++  H   + N+   TLVLK++    +G Y  +  +R G+
Sbjct: 751 KDSGHFELLQNEDVFTLVLKNVQPWHAGQYEILLKNRVGE 790



 Score = 89.4 bits (212), Expect = 5e-16
 Identities = 92/300 (30%), Positives = 126/300 (42%), Gaps = 30/300 (10%)

Query: 20  DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
           D  V   Q   L C   G+P+P + W   G   +   H SI  AG           +  D
Sbjct: 510 DSVVIEGQDFVLRCSVQGTPAPRVTWLLNGQ-PIQFAH-SICEAGVAEL--HIQDALPED 565

Query: 80  AGVYWCEATNSYGTARSRNATLHVAVLR----EEFRLEP-ESKQSA----QG--DTVVLE 128
            G Y C A N+ G   S +AT+ V   +     E RL P  SK  A    QG  D  V++
Sbjct: 566 RGTYTCLAENAMGQV-SCSATVTVQEKKGEGEREHRLSPARSKPIAPIFLQGLSDLKVMD 624

Query: 129 ------CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCI 181
                  +   G+P P V W  +G  +    D       G + L IQ+    D G Y C 
Sbjct: 625 GSQVTMTVQVSGNPPPEVIWLHDGNEIQESEDFHFEQKGGWHSLCIQEVFPEDTGTYTCE 684

Query: 182 ARNAAG-TRESAIATLKI-H--IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
           A N+AG  R  A+ T++  H   +P+ I+ P  V A  G SV   C + GDP P V W R
Sbjct: 685 AWNSAGEVRTRAVLTVQEPHDGTQPWFISKPRSVTATLGQSVLISCAIAGDPFPTVHWLR 744

Query: 238 SAGGGNMPLGRVKVL---DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
                +   G  ++L   D  +L L NV     G+Y    +N VG  S    L +++ PS
Sbjct: 745 DGRALSKDSGHFELLQNEDVFTLVLKNVQPWHAGQYEILLKNRVGECSCQVSLMLHNSPS 804



 Score = 70.1 bits (164), Expect = 3e-10
 Identities = 82/312 (26%), Positives = 117/312 (37%), Gaps = 36/312 (11%)

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---SLR 258
           P   + P+      G +V F C V G P PDV W           G  +V +DG    L 
Sbjct: 402 PRFESQPQSQEVTEGQTVKFICEVSGIPKPDVGWFLEGIPVRRREGITEVYEDGVSHHLC 461

Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA------RF 312
           L      D  +YSC A NS+G VS S  L V  P     +P+  +V   +V         
Sbjct: 462 LLRARTRDSRKYSCTASNSLGQVSCSWSLLVDRPNLAQTAPSFSSVLKDSVVIEGQDFVL 521

Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
            C+  G P P + W + G + I F        H+     GV  L I D    D R T  C
Sbjct: 522 RCSVQGTPAPRVTWLLNG-QPIQFA-------HSICE-AGVAELHIQDALPED-RGTYTC 571

Query: 373 SAVNYAGSSFVRGKLTV---TSDDDRP-----------PPIITNGPSNQTLPIKSMAVFP 418
            A N  G       +TV     + +R             PI   G S+  +   S     
Sbjct: 572 LAENAMGQVSCSATVTVQEKKGEGEREHRLSPARSKPIAPIFLQGLSDLKVMDGSQVTMT 631

Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGK 475
                 P P + W  +G  + ++   +    G   +L ++++   D+GTYTC A +  G+
Sbjct: 632 VQVSGNPPPEVIWLHDGNEIQESEDFHFEQKGGWHSLCIQEVFPEDTGTYTCEAWNSAGE 691

Query: 476 YVWSGALLVDSP 487
                 L V  P
Sbjct: 692 VRTRAVLTVQEP 703



 Score = 64.1 bits (149), Expect = 2e-08
 Identities = 53/198 (26%), Positives = 83/198 (41%), Gaps = 10/198 (5%)

Query: 11  APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
           AP  ++   D+ V      T+  +  G+P P + W   G  +           GG   L 
Sbjct: 610 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHDGNEIQESEDFHFEQKGGWHSL- 668

Query: 71  ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE----FRLEPESKQSAQGDTVV 126
                   D G Y CEA NS G  R+R A L V    +     F  +P S  +  G +V+
Sbjct: 669 CIQEVFPEDTGTYTCEAWNSAGEVRTR-AVLTVQEPHDGTQPWFISKPRSVTATLGQSVL 727

Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGD--SRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
           + C    G P P V+W ++G+ L  D      +   D   LV+++ +   AG+Y+ + +N
Sbjct: 728 ISC-AIAGDPFPTVHWLRDGRALSKDSGHFELLQNEDVFTLVLKNVQPWHAGQYEILLKN 786

Query: 185 AAGTRESAIATLKIHIKP 202
             G   S   +L +H  P
Sbjct: 787 RVG-ECSCQVSLMLHNSP 803



 Score = 56.4 bits (130), Expect = 4e-06
 Identities = 60/223 (26%), Positives = 85/223 (38%), Gaps = 21/223 (9%)

Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF-D 351
           P     P S  V  G   +F C  +G P+P + W +EG      P   R+    T V+ D
Sbjct: 402 PRFESQPQSQEVTEGQTVKFICEVSGIPKPDVGWFLEG-----IPVRRREGI--TEVYED 454

Query: 352 GVTV-LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
           GV+  L +      DSR    C+A N  G       L V    DRP  +    PS  ++ 
Sbjct: 455 GVSHHLCLLRARTRDSRK-YSCTASNSLGQVSCSWSLLV----DRPN-LAQTAPSFSSVL 508

Query: 411 IKSMA------VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGT 464
             S+       V  C+   TP P + W   G+ +   H         L ++D    D GT
Sbjct: 509 KDSVVIEGQDFVLRCSVQGTPAPRVTWLLNGQPIQFAHSICEAGVAELHIQDALPEDRGT 568

Query: 465 YTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPP 507
           YTC+A +  G+   S  + V           R +   S P  P
Sbjct: 569 YTCLAENAMGQVSCSATVTVQEKKGEGEREHRLSPARSKPIAP 611



 Score = 54.0 bits (124), Expect = 2e-05
 Identities = 61/216 (28%), Positives = 87/216 (40%), Gaps = 41/216 (18%)

Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVI 167
           F L P +    +G T   E    RG PEP V W + GQ +   G   +     G  +LVI
Sbjct: 35  FILPPRNLCVKEGATAKFEGRV-RGYPEPQVTWHRKGQAITNGGRFLLDCGVRGTFSLVI 93

Query: 168 QDARQTDAGRYQCIARNAAGTRESAIA------TLKIHIKPYL-------------ITG- 207
              R+ D G+Y C A N +G R+  +       ++K   +P L             I G 
Sbjct: 94  HTVREEDKGKYTCEASNGSGARQVTVELTVEGNSMKKRDQPVLSKASGFPGETRPSIWGE 153

Query: 208 -PEDVVAQTGSSVT-------FQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGS 256
            P     + G +V        F C++ G P P V W +    GN+PL    RV + +   
Sbjct: 154 CPPKFATKLGRAVVKEGQMWRFSCKITGRPPPQVTWLK----GNVPLQPSARVSMSEKNG 209

Query: 257 ---LRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
              L +  V   D G Y+C   N  G  S S  L++
Sbjct: 210 MQILEIRGVTRDDLGVYTCMVVNGSGKASMSAELSI 245



 Score = 52.8 bits (121), Expect = 5e-05
 Identities = 31/101 (30%), Positives = 52/101 (51%), Gaps = 3/101 (2%)

Query: 192  AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW-RRSAGGGNMPLGRVK 250
            A+A  K H+KPY      D+    GS+  F C++ G P P+V+W +           ++ 
Sbjct: 1821 AVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID 1880

Query: 251  VLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
              +DG  SL + +V   D+ +Y+C+A NS+G  + +  L V
Sbjct: 1881 YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1921



 Score = 51.6 bits (118), Expect = 1e-04
 Identities = 36/123 (29%), Positives = 56/123 (45%), Gaps = 12/123 (9%)

Query: 504  PGPPT-KPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
            P PP   P   ++  +S+TLSW  ++  G S++  Y VE++  E           + W  
Sbjct: 1353 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYNVEIWDTE----------DKVWKE 1402

Query: 563  IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSN 622
            +A     T + V+ L+P   Y F VR  N +G S PS  S+   VG+      +   VS+
Sbjct: 1403 LAT-CRSTSFNVQDLLPDREYKFRVRAVNVYGTSEPSQESELTAVGEKPEEPKDEVEVSD 1461

Query: 623  STE 625
              E
Sbjct: 1462 DDE 1464



 Score = 49.6 bits (113), Expect = 5e-04
 Identities = 34/104 (32%), Positives = 52/104 (50%), Gaps = 7/104 (6%)

Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250
           S ++++ +   P  I  P ++  + G++  F+ RV G P P V W R   G  +  G   
Sbjct: 22  SKVSSMPLTEAPAFILPPRNLCVKEGATAKFEGRVRGYPEPQVTWHRK--GQAITNGGRF 79

Query: 251 VLDDG-----SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
           +LD G     SL +  V   D+G+Y+CEA N  GA   +  LTV
Sbjct: 80  LLDCGVRGTFSLVIHTVREEDKGKYTCEASNGSGARQVTVELTV 123



 Score = 46.0 bits (104), Expect = 0.006
 Identities = 33/113 (29%), Positives = 48/113 (42%), Gaps = 4/113 (3%)

Query: 379 GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438
           G+ FV G +   S  +   P   + P +Q +       F C     P+P + W+ EG  +
Sbjct: 383 GNKFVTGNIPRESQRESTFPRFESQPQSQEVTEGQTVKFICEVSGIPKPDVGWFLEGIPV 442

Query: 439 IQNHR-RNVTNDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
            +      V  DG    L L      DS  Y+C AS+  G+   S +LLVD P
Sbjct: 443 RRREGITEVYEDGVSHHLCLLRARTRDSRKYSCTASNSLGQVSCSWSLLVDRP 495



 Score = 42.7 bits (96), Expect = 0.059
 Identities = 33/116 (28%), Positives = 44/116 (37%), Gaps = 3/116 (2%)

Query: 9   GEAPYIIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
           GE P      L   V +  Q    +C+  G P P + W KG V +      S+    G+ 
Sbjct: 152 GECPPKFATKLGRAVVKEGQMWRFSCKITGRPPPQVTWLKGNVPLQPSARVSMSEKNGMQ 211

Query: 68  FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
            L    G    D GVY C   N  G A S +A L +  L    RL     ++   D
Sbjct: 212 ILE-IRGVTRDDLGVYTCMVVNGSGKA-SMSAELSIPGLDNASRLAVRGTKAPSPD 265



 Score = 42.3 bits (95), Expect = 0.078
 Identities = 31/98 (31%), Positives = 44/98 (44%), Gaps = 7/98 (7%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG--GLF 67
           EAP  I  P ++ V     A    R  G P P + W++ G   +++  R +L  G  G F
Sbjct: 31  EAPAFILPPRNLCVKEGATAKFEGRVRGYPEPQVTWHRKG-QAITNGGRFLLDCGVRGTF 89

Query: 68  FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV 105
            L   H     D G Y CEA+N  G   +R  T+ + V
Sbjct: 90  SL-VIHTVREEDKGKYTCEASNGSG---ARQVTVELTV 123



 Score = 41.1 bits (92), Expect = 0.18
 Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 6/87 (6%)

Query: 209  EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL-DDGS---LRLDNVIL 264
            +DV    G  +  QC+V  DP   V W  S  G  +   +  VL  +GS   + ++  + 
Sbjct: 1127 QDVHVAEGEKLLLQCQVISDPPATVTW--SLNGKTLKTTKFIVLAQEGSRFSVSIEKALP 1184

Query: 265  ADEGEYSCEAENSVGAVSASGYLTVYD 291
             D G Y C A+NS G    S  +TV D
Sbjct: 1185 EDRGLYKCVAKNSAGQAECSCQVTVDD 1211



 Score = 39.9 bits (89), Expect = 0.41
 Identities = 33/112 (29%), Positives = 45/112 (40%), Gaps = 3/112 (2%)

Query: 7    TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66
            + G AP   E+  DV VA  +   L C+    P   + W   G   +  T   +L   G 
Sbjct: 1115 SQGSAPVFKEKLQDVHVAEGEKLLLQCQVISDPPATVTWSLNG-KTLKTTKFIVLAQEGS 1173

Query: 67   FFLRATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESK 117
             F  +    +  D G+Y C A NS G A  S   T+  A   E  +  PE K
Sbjct: 1174 RFSVSIEKALPEDRGLYKCVAKNSAGQAECSCQVTVDDAQTSENTK-APEMK 1224



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 18/62 (29%), Positives = 28/62 (45%), Gaps = 1/62 (1%)

Query: 9   GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT-HRSILPAGGLF 67
           G  P+ I +P  VT    Q   ++C   G P P + W + G  +  D+ H  +L    +F
Sbjct: 706 GTQPWFISKPRSVTATLGQSVLISCAIAGDPFPTVHWLRDGRALSKDSGHFELLQNEDVF 765

Query: 68  FL 69
            L
Sbjct: 766 TL 767



 Score = 37.5 bits (83), Expect = 2.2
 Identities = 26/103 (25%), Positives = 47/103 (45%), Gaps = 7/103 (6%)

Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
           PP          V+ G + RF+C  TGRP P + W ++GN     P +      + +  +
Sbjct: 155 PPKFATKLGRAVVKEGQMWRFSCKITGRPPPQVTW-LKGN----VP-LQPSARVSMSEKN 208

Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394
           G+ +L I    ++D      C  VN +G + +  +L++   D+
Sbjct: 209 GMQILEIRGVTRDD-LGVYTCMVVNGSGKASMSAELSIPGLDN 250



 Score = 37.5 bits (83), Expect = 2.2
 Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 6/84 (7%)

Query: 110  FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LV 166
            F+ + +    A+G+ ++L+C      P   V W  NG+TL       + L   G+   + 
Sbjct: 1122 FKEKLQDVHVAEGEKLLLQC-QVISDPPATVTWSLNGKTL--KTTKFIVLAQEGSRFSVS 1178

Query: 167  IQDARQTDAGRYQCIARNAAGTRE 190
            I+ A   D G Y+C+A+N+AG  E
Sbjct: 1179 IEKALPEDRGLYKCVAKNSAGQAE 1202


>UniRef50_Q9UPX0 Cluster: Protein turtle homolog B precursor; n=21;
           Euteleostomi|Rep: Protein turtle homolog B precursor -
           Homo sapiens (Human)
          Length = 1349

 Score =  102 bits (245), Expect = 5e-20
 Identities = 87/301 (28%), Positives = 128/301 (42%), Gaps = 17/301 (5%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSP-AIRWY--KGGVLVVSDTHRS--ILPAGGL 66
           P+I+  P ++TV   Q A L CRA   P      WY     V   +D      IL  G L
Sbjct: 229 PFIVSPPENITVNISQDALLTCRAEAYPGNLTYTWYWQDENVYFQNDLKLRVRILIDGTL 288

Query: 67  FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
              R        D+G Y C  +NS G + S +A L V        + P       G    
Sbjct: 289 IIFRVKP----EDSGKYTCVPSNSLGRSPSASAYLTVQYPARVLNMPPVIYVPV-GIHGY 343

Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
           + C      P   V W K+G+ L  + +    L++ G++ I++A +   G Y C+  N  
Sbjct: 344 IRCPVDAEPPATVVKWNKDGRPLQVEKNLGWTLMEDGSIRIEEATEEALGTYTCVPYNTL 403

Query: 187 GTR-ESAIATLKIHIKPYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
           GT  +SA A L +   PY    P  +   + G  +   C   GDP P + WR+    G  
Sbjct: 404 GTMGQSAPARLVLKDPPYFTVLPGWEYRQEAGRELLIPCAAAGDPFPVITWRKV---GKP 460

Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
              +   L  GSL+   +   D GE+ C A N V +++AS +LTV    +   +P SV V
Sbjct: 461 SRSKHSALPSGSLQFRALSKEDHGEWECVATNVVTSITASTHLTVIG--TSPHAPGSVRV 518

Query: 305 E 305
           +
Sbjct: 519 Q 519



 Score = 99.5 bits (237), Expect = 5e-19
 Identities = 97/366 (26%), Positives = 151/366 (41%), Gaps = 27/366 (7%)

Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT 173
           P+  ++ +G ++ + C    G+P+P V W K G TLL  G S  + V  G+L +    + 
Sbjct: 146 PQYIEAKEGGSITMTCTA-FGNPKPIVTWLKEG-TLL--GASGKYQVSDGSLTVTSVSRE 201

Query: 174 DAGRYQCIARNAAGTRESAIAT-LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--- 229
           D G Y C A +  G  E+   T L +   P++++ PE++           CR    P   
Sbjct: 202 DRGAYTCRAYSIQG--EAVHTTHLLVQGPPFIVSPPENITVNISQDALLTCRAEAYPGNL 259

Query: 230 LPDVLWR-RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG-AVSASGYL 287
                W+  +    N    RV++L DG+L +  V   D G+Y+C   NS+G + SAS YL
Sbjct: 260 TYTWYWQDENVYFQNDLKLRVRILIDGTLIIFRVKPEDSGKYTCVPSNSLGRSPSASAYL 319

Query: 288 TVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF-WSVEGNRTIIFPGMSRDKYHA 346
           TV  P  +   P  + V  G      C     P  T+  W+ +G      P         
Sbjct: 320 TVQYPARVLNMPPVIYVPVGIHGYIRCPVDAEPPATVVKWNKDGR-----PLQVEKNLGW 374

Query: 347 TAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPS- 405
           T + DG   + I +  + ++  T  C   N  G+        +   D   PP  T  P  
Sbjct: 375 TLMEDGS--IRIEEATE-EALGTYTCVPYNTLGTMGQSAPARLVLKD---PPYFTVLPGW 428

Query: 406 NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465
                     + PC A   P P+I W   G+     H  +    G+L  + L K D G +
Sbjct: 429 EYRQEAGRELLIPCAAAGDPFPVITWRKVGKPSRSKH--SALPSGSLQFRALSKEDHGEW 486

Query: 466 TCVASS 471
            CVA++
Sbjct: 487 ECVATN 492



 Score = 95.5 bits (227), Expect = 8e-18
 Identities = 82/336 (24%), Positives = 132/336 (39%), Gaps = 19/336 (5%)

Query: 5   YVTSGEAPYIIEQPLDVTVARHQPA-TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
           ++T    P   E P     A+   + T+ C A G+P P + W K G L+ +     +   
Sbjct: 132 HLTINAPPTFTETPPQYIEAKEGGSITMTCTAFGNPKPIVTWLKEGTLLGASGKYQVSD- 190

Query: 64  GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-G 122
           G L     +      D G Y C A +  G A     T H+ V    F + P    +    
Sbjct: 191 GSLTVTSVSR----EDRGAYTCRAYSIQGEAVH---TTHLLVQGPPFIVSPPENITVNIS 243

Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS--RMHLVDGGNLVIQDARQTDAGRYQC 180
              +L C            W    + + F  D   R+ ++  G L+I   +  D+G+Y C
Sbjct: 244 QDALLTCRAEAYPGNLTYTWYWQDENVYFQNDLKLRVRILIDGTLIIFRVKPEDSGKYTC 303

Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL-WRRSA 239
           +  N+ G   SA A L +     ++  P  +    G     +C V  +P   V+ W +  
Sbjct: 304 VPSNSLGRSPSASAYLTVQYPARVLNMPPVIYVPVGIHGYIRCPVDAEPPATVVKWNKDG 363

Query: 240 GGGNMP--LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV--SASGYLTVYDPPSI 295
               +   LG   +++DGS+R++       G Y+C   N++G +  SA   L + DPP  
Sbjct: 364 RPLQVEKNLGWT-LMEDGSIRIEEATEEALGTYTCVPYNTLGTMGQSAPARLVLKDPPYF 422

Query: 296 NLSPN-SVNVESGNVARFTCTATGRPEPTMFWSVEG 330
            + P      E+G      C A G P P + W   G
Sbjct: 423 TVLPGWEYRQEAGRELLIPCAAAGDPFPVITWRKVG 458



 Score = 87.4 bits (207), Expect = 2e-15
 Identities = 77/248 (31%), Positives = 111/248 (44%), Gaps = 27/248 (10%)

Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEA-----ENSVGAVSASGYLTVYDPPSINLSPNS 301
           GR  + D  SLRL+ V   D+G Y C+      +       +  +LT+  PP+   +P  
Sbjct: 88  GRASLHDKASLRLEQVRSEDQGWYECKVLMLDQQYDTFHNGSWVHLTINAPPTFTETPPQ 147

Query: 302 -VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
            +  + G     TCTA G P+P + W  EG  T++  G S  KY    V DG   LT+  
Sbjct: 148 YIEAKEGGSITMTCTAFGNPKPIVTWLKEG--TLL--GAS-GKYQ---VSDGS--LTVTS 197

Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
             + D R    C A +  G +     L V       PP I + P N T+ I   A+  C 
Sbjct: 198 VSRED-RGAYTCRAYSIQGEAVHTTHLLVQG-----PPFIVSPPENITVNISQDALLTCR 251

Query: 421 AICTPEPII-AWYFEGEAL-IQNH---RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
           A   P  +   WY++ E +  QN    R  +  DGTL++  +   DSG YTCV S+  G+
Sbjct: 252 AEAYPGNLTYTWYWQDENVYFQNDLKLRVRILIDGTLIIFRVKPEDSGKYTCVPSNSLGR 311

Query: 476 YVWSGALL 483
              + A L
Sbjct: 312 SPSASAYL 319



 Score = 85.4 bits (202), Expect = 8e-15
 Identities = 98/383 (25%), Positives = 155/383 (40%), Gaps = 36/383 (9%)

Query: 111 RLEPESKQSAQGDTVVLEC---LPPRGSPEPNVY-WKKNGQTL-LF------------DG 153
           R EPE   +  G++VVL C    P  G P P V  W K G  + +F            + 
Sbjct: 27  REEPEFVTARAGESVVLRCDVIHPVTGQPPPYVVEWFKFGVPIPIFIKFGYYPPHVDPEY 86

Query: 154 DSRMHLVDGGNLVIQDARQTDAGRYQC----IARNAAGTRESAIATLKIHIKP-YLITGP 208
             R  L D  +L ++  R  D G Y+C    + +        +   L I+  P +  T P
Sbjct: 87  AGRASLHDKASLRLEQVRSEDQGWYECKVLMLDQQYDTFHNGSWVHLTINAPPTFTETPP 146

Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268
           + + A+ G S+T  C   G+P P V W +  G      G+ +V  DGSL + +V   D G
Sbjct: 147 QYIEAKEGGSITMTCTAFGNPKPIVTWLKE-GTLLGASGKYQV-SDGSLTVTSVSREDRG 204

Query: 269 EYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328
            Y+C A +  G    + +L V  PP I   P ++ V     A  TC A   P    +   
Sbjct: 205 AYTCRAYSIQGEAVHTTHLLVQGPPFIVSPPENITVNISQDALLTCRAEAYPGNLTYTWY 264

Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT 388
             +  + F   +  K     + DG T++      ++  + T V S  +   S      LT
Sbjct: 265 WQDENVYF--QNDLKLRVRILIDG-TLIIFRVKPEDSGKYTCVPSN-SLGRSPSASAYLT 320

Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC-TPEPIIAWYFEGEAL--IQNHRRN 445
           V     + P  + N P    +P+       C      P  ++ W  +G  L   +N    
Sbjct: 321 V-----QYPARVLNMPPVIYVPVGIHGYIRCPVDAEPPATVVKWNKDGRPLQVEKNLGWT 375

Query: 446 VTNDGTLVLKDLDKSDSGTYTCV 468
           +  DG++ +++  +   GTYTCV
Sbjct: 376 LMEDGSIRIEEATEEALGTYTCV 398



 Score = 53.6 bits (123), Expect = 3e-05
 Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 2/92 (2%)

Query: 397 PPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLK 455
           PP  T  P       +  ++   CTA   P+PI+ W  EG  L  + +  V+ DG+L + 
Sbjct: 138 PPTFTETPPQYIEAKEGGSITMTCTAFGNPKPIVTWLKEGTLLGASGKYQVS-DGSLTVT 196

Query: 456 DLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
            + + D G YTC A S  G+ V +  LLV  P
Sbjct: 197 SVSREDRGAYTCRAYSIQGEAVHTTHLLVQGP 228



 Score = 42.3 bits (95), Expect = 0.078
 Identities = 61/260 (23%), Positives = 112/260 (43%), Gaps = 22/260 (8%)

Query: 39  PSPAIRWYKGG--VLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGT-AR 95
           P+  ++W K G  + V  +   +++  G +    AT   +    G Y C   N+ GT  +
Sbjct: 353 PATVVKWNKDGRPLQVEKNLGWTLMEDGSIRIEEATEEAL----GTYTCVPYNTLGTMGQ 408

Query: 96  SRNATLHVAVLREE--FRLEP--ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLF 151
           S  A L   VL++   F + P  E +Q A G  +++ C    G P P + W+K G+    
Sbjct: 409 SAPARL---VLKDPPYFTVLPGWEYRQEA-GRELLIPCAAA-GDPFPVITWRKVGKP--- 460

Query: 152 DGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDV 211
              S+   +  G+L  +   + D G ++C+A N   +  ++     I   P+        
Sbjct: 461 -SRSKHSALPSGSLQFRALSKEDHGEWECVATNVVTSITASTHLTVIGTSPHAPGSVRVQ 519

Query: 212 VAQTGSSVTFQCRV-GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGE 269
           V+ T ++V+++    GG      +W + A  G      + V    S L +D +      +
Sbjct: 520 VSMTTANVSWEPGYDGGYEQTFSVWMKRAQFGPHDWLSLPVPPGPSWLLVDTLEPETAYQ 579

Query: 270 YSCEAENSVGAVSASGYLTV 289
           +S  A+N +G  + S  +TV
Sbjct: 580 FSVLAQNKLGTSAFSEVVTV 599


>UniRef50_UPI0000E48847 Cluster: PREDICTED: similar to titin isoform
            N2-A; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
            similar to titin isoform N2-A - Strongylocentrotus
            purpuratus
          Length = 10984

 Score =  102 bits (244), Expect = 7e-20
 Identities = 144/591 (24%), Positives = 226/591 (38%), Gaps = 55/591 (9%)

Query: 21   VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFFLRATHGRVHSD 79
            V     +PA   C      +  I W K    +  D  +   + +G    L+     V SD
Sbjct: 1360 VQAVEDEPAVFTCEISDDNAEVI-WLKNEEEIKPDDEKYEFVVSGKKRGLKIKSTDV-SD 1417

Query: 80   AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
               + C+  +   +A S   T H+  +    +   + K     + VV EC         +
Sbjct: 1418 TAEFTCKTKDKTSSA-SLTVTEHIPTISHTLK---DVKIEEGSNEVVFEC--ETDVETAD 1471

Query: 140  VYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
            V W   G+ ++ D    +    G   +L+++D    DAG + C      G  E+ IA L 
Sbjct: 1472 VAWLHKGKDIVEDNSKFVIKRKGRRHSLIVKDVSVEDAGEFTC----RIGVHET-IAELI 1526

Query: 198  IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS- 256
            + ++ +L   P++  A  G  +TF+  +  D   DV W +  G    P   VK++ DG  
Sbjct: 1527 VEVE-FLAPLPKEQSAIPGDEITFEVELTKDT-EDVFWLKD-GQKIKPGDNVKIVKDGKK 1583

Query: 257  --LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN--SVNVESGNVARF 312
              L +  V   D+  YS  A    G       L V  PP IN+ P   +++V++G     
Sbjct: 1584 HKLIIKKVDFDDDAVYSFNA----GDQKCDCNLNVSAPPKINVDPKLTNISVKAGTKIAI 1639

Query: 313  TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
              T TG P     WS +G+  I      R K  A         LTI+ T+++D   T   
Sbjct: 1640 EATVTGSPAAVTTWS-KGDTPI--ESTKRFKIEAGKGPKASIRLTIDKTERSDL-GTYTL 1695

Query: 373  SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
            +A N  G+      + V  D  +PP   T+    +T P     V+         P+I + 
Sbjct: 1696 TAANDLGTDTAIIFIIVL-DKPQPP---TSLSITETTPESVTLVWTAPEDDGGSPVIEYV 1751

Query: 433  FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
             E   + +N    V     L  + + K   G       S   +   S       P+    
Sbjct: 1752 IEKRDMKRNTWTKVDTTSELTCR-VPKLVEGNEYLFRVSATNELGTSEPFTTSEPVTAKY 1810

Query: 493  HFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNN 552
             F        +P  P+KP T +V  T +TL+W+  +  G S + GY +E           
Sbjct: 1811 QF-------DVPHAPSKPETSDVIQTEMTLTWTPPDFNGGSEVTGYIIE----------R 1853

Query: 553  TPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602
               +   WV I +  V +  + VK LI G +Y F V   N  G S PS  S
Sbjct: 1854 KEADKTRWVKITKETVTELTFRVKDLIEGTSYEFRVYAINKAGTSKPSEPS 1904



 Score = 91.1 bits (216), Expect = 2e-16
 Identities = 197/828 (23%), Positives = 309/828 (37%), Gaps = 115/828 (13%)

Query: 15   IEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
            I +PL D T A      L C      +P ++W K G   ++   + ++ + G        
Sbjct: 1264 ITKPLEDTTTAFETTVVLECEVDNEKAP-VKWMKNGK-EITKMPKYLMESKGKKRRLTIF 1321

Query: 74   GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
              +  D G Y C   +      S  A L V     EF  E +S Q+ + +  V  C    
Sbjct: 1322 ETIPEDEGDYTCVVGDE-----STVAVLAVEPAPIEFLSEIQSVQAVEDEPAVFTCEISD 1376

Query: 134  GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRES 191
             + E  V W KN + +  D +    +V G    L I+    +D   + C  ++      S
Sbjct: 1377 DNAE--VIWLKNEEEIKPDDEKYEFVVSGKKRGLKIKSTDVSDTAEFTCKTKDKTS---S 1431

Query: 192  AIATLKIHIKPYLITGPEDVVAQTGSS-VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250
            A  T+  HI P +    +DV  + GS+ V F+C    +   DV W            +  
Sbjct: 1432 ASLTVTEHI-PTISHTLKDVKIEEGSNEVVFECETDVETA-DVAWLHKGKDIVEDNSKFV 1489

Query: 251  VLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESG 307
            +   G   SL + +V + D GE++C     +G       L V +   +   P   +   G
Sbjct: 1490 IKRKGRRHSLIVKDVSVEDAGEFTCR----IGVHETIAELIV-EVEFLAPLPKEQSAIPG 1544

Query: 308  NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT-VLTINDTDKNDS 366
            +   F    T   E  +FW  +G +  I PG +        V DG    L I   D +D 
Sbjct: 1545 DEITFEVELTKDTED-VFWLKDGQK--IKPGDN-----VKIVKDGKKHKLIIKKVDFDDD 1596

Query: 367  RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
                   + N AG       L V++     PP I   P    + +K+       A  T  
Sbjct: 1597 ----AVYSFN-AGDQKCDCNLNVSA-----PPKINVDPKLTNISVKAGTKIAIEATVTGS 1646

Query: 427  PI-IAWYFEGEALIQNHRRNVTNDGT-------LVLKDLDKSDSGTYTCVASSRHGKYVW 478
            P  +  + +G+  I++ +R     G        L +   ++SD GTYT  A++       
Sbjct: 1647 PAAVTTWSKGDTPIESTKRFKIEAGKGPKASIRLTIDKTERSDLGTYTLTAAN------- 1699

Query: 479  SGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGY 538
                  D   +  I F    D    P PPT       T  SVTL W+     G S ++ Y
Sbjct: 1700 ------DLGTDTAIIFIIVLDK---PQPPTSLSITETTPESVTLVWTAPEDDGGSPVIEY 1750

Query: 539  QVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
             +E          +  RN+  W  +      T  V K L+ G  Y+F V   N  G S P
Sbjct: 1751 VIEK--------RDMKRNT--WTKVDTTSELTCRVPK-LVEGNEYLFRVSATNELGTSEP 1799

Query: 599  SPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNF 658
               S+ VT                  +Y+ ++   H     E + +    + L W   +F
Sbjct: 1800 FTTSEPVTA-----------------KYQFDV--PHAPSKPETSDVIQTEMTLTWTPPDF 1840

Query: 659  Y---YLEGLFIYFRPLDNIT-IEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKF 714
                 + G  I  +  D    ++   +T+        F +  L + T YEF +    K  
Sbjct: 1841 NGGSEVTGYIIERKEADKTRWVKITKETVTELT----FRVKDLIEGTSYEFRVYAINKAG 1896

Query: 715  EGKPSNSRV---AQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVV 771
              KPS       A+   DVP GPP       +N TT+ + W+PPE       +TGY  V+
Sbjct: 1897 TSKPSEPSTPTKAKAPYDVP-GPPAQPTCENVNKTTITVSWTPPE-DDGGSPVTGY--VI 1952

Query: 772  NWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819
               DV   + +      V + T   +++LT G  Y  +I+AE   G+G
Sbjct: 1953 ERCDVSRGRWVKCNRDKVTELT-FTVSDLTDGGQYQFRISAENAAGVG 1999



 Score = 82.6 bits (195), Expect = 6e-14
 Identities = 89/325 (27%), Positives = 141/325 (43%), Gaps = 36/325 (11%)

Query: 502  SLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV 561
            S P  P +P   NVT  S TL+WS     G SSI GY +E   ++  S    PR +R   
Sbjct: 6571 SQPAAPNEPQISNVTADSATLTWSPPRDDGGSSITGYFIE--KKDKFS----PRWTR--- 6621

Query: 562  VIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVS 621
            V    V  T + V +L+PG  Y F V  +N  G S PS  ++S  V    N      G  
Sbjct: 6622 VNHDAVTDTKFTVPALVPGEEYQFRVVAQNKAGASKPSEPTESTLVRSPFNE----PGAP 6677

Query: 622  NSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMK 681
             + E  N  +T+  + L    P      +     +  YY+E         D +++ +   
Sbjct: 6678 GAPETSN--VTETTLTLTWTPPFSDGGSR-----ITGYYVE-------KKDRMSLRWSPV 6723

Query: 682  TILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRV---AQTLDDVPDGPPINI 738
                + D    ++T L + T+YEF ++        KPS       A++  D+P  P    
Sbjct: 6724 NFESTEDTK-LKVTGLTEGTEYEFRVVAENDAGRSKPSAPSYPVKAKSPFDLPSAPG-TP 6781

Query: 739  EMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMT 798
             +  +++T + L+W+PPE      IIT    +V   +  + +  V I+      T+  +T
Sbjct: 6782 SISDISSTNMTLRWAPPESDGGTVIIT---FIVERREQFSTR-WVQISRFDFTETTFSVT 6837

Query: 799  NLTSGVSYSVQIAAETIIGLGPFSQ 823
             L  G  Y  ++AA+  IG+G FS+
Sbjct: 6838 GLKDGNDYEFRVAAKNKIGIGKFSE 6862



 Score = 82.6 bits (195), Expect = 6e-14
 Identities = 115/440 (26%), Positives = 177/440 (40%), Gaps = 52/440 (11%)

Query: 178  YQCIARNAAG----TRESAIATLKIHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPD 232
            ++  A N AG    ++ SA    K  I+      P +DV A+ G  VT +CR+  +P  +
Sbjct: 9035 FRVAAENEAGLGAFSKTSAPIVSKTPIELAEFVEPLKDVSAKAGKIVTLECRIS-NPNAE 9093

Query: 233  VLWRRSAGGGNMPLGRVKVLDDGSLR---LDNVILADEGEYSCEAENSVGAVSASGYLTV 289
            V W +  G       RV  + +G  R   L NV   D G+YSCE     G  S S +L+V
Sbjct: 9094 VKWMKD-GFQIFGYDRVNEIKEGQRRAITLRNVGDRDTGKYSCEC----GKQSTSCWLSV 9148

Query: 290  YDPPSINLSP--NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
              PP+I++    + V V++GN  R     TG P P + W     R      +S D     
Sbjct: 9149 TAPPTIDVKAYKDVVVVKTGNTLRLLVPYTGCPSPKVEWHRHDAR------ISEDTRTHI 9202

Query: 348  AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407
               D  T +TI +  + D+    + +  N AG      ++ V    D P      GP   
Sbjct: 9203 ETRDNRTQITIRNVVRGDTGKFSI-TLTNEAGQETAIIRVNVI---DVP------GPPTG 9252

Query: 408  TLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGT-YT 466
             L I  +    C ++    P      +G + IQ++          +   +    S   +T
Sbjct: 9253 PLEITDVGRH-CVSLSWEPP----KDDGGSPIQSYTVEQREANRRMWTSVSNYVSHVPFT 9307

Query: 467  CVASSRHGKYVWSGALLVDSPINPNIHFFRAADV---SSLPGPPTKPITHNVTDTSVTLS 523
                S   +Y +       + + P +H      +    S+P PP KP   NV    +TL+
Sbjct: 9308 VSGLSEKVEYEFRVCAENINGVGPPLHGIEPVVIVAPYSVPTPPGKPEISNVQRDRMTLT 9367

Query: 524  WSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGIT 582
            WS+ +  G   I GY +E   RE          S+ W  + R  +  T + +K L  G  
Sbjct: 9368 WSEPSHDGGKPIQGYIIE--RRENF--------SKQWNRVNRDLIKDTTFTIKGLTEGSN 9417

Query: 583  YMFIVRTENSHGLSGPSPVS 602
            Y F +   N  G+  PS VS
Sbjct: 9418 YEFRISAVNDTGIGNPSEVS 9437



 Score = 79.8 bits (188), Expect = 4e-13
 Identities = 120/500 (24%), Positives = 196/500 (39%), Gaps = 56/500 (11%)

Query: 130  LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGT 188
            +P + +P P V W +NG T+       +   + G  L  + A +TD+G Y   A N AG 
Sbjct: 8491 IPYKATPTPTVSWTQNGDTVQKSNRITIDSNNYGTTLTARTAERTDSGDYVIRASNKAG- 8549

Query: 189  RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV----GGDPLPD-VLWRRSAGGGN 243
             ++   T+ +   P    GP  +V    + VT         GG P+   VL +R  G G+
Sbjct: 8550 EDTVTVTVNVVDSPSPPQGPLALVKLGSNEVTLSWSRPRDDGGSPITGYVLEKREGGYGS 8609

Query: 244  MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA--------VSASGYLTVYDPPSI 295
                  K+  D + R+  +    E ++   AEN++G         +   G   V D P  
Sbjct: 8610 WTNVSSKI-PDTTFRVTKLTEDREYQFRVRAENNLGVSEPLESERIIPKGDYDVPDQPG- 8667

Query: 296  NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
             +  +++  +S ++        G    T +   +  R     G +R  Y    +   + V
Sbjct: 8668 KIKVDTIQSDSVSLTWSRPQRDGGAPVTGYIVEKRERGQPEAGWNRTSYKPV-MDTTIRV 8726

Query: 356  LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT--VTSDDDRPPPIITNGPSNQTLPIKS 413
              +++  + + R     SAVN AG S         +       P I         + +++
Sbjct: 8727 PRLSEGKEYEFR----VSAVNKAGMSTPAATAAPVIVERPSYAPKIDLGSQFRDVITVRA 8782

Query: 414  MAVFPCTAIC--TPEPIIAWYFEGEALIQNHRR----NVTNDGTLVLKDLDKSDSGTYTC 467
              +F        TP P +AW  + E  + + RR      T    L  KD  ++DSGTYT 
Sbjct: 8783 GTLFHLDVPISGTPTPTVAWLMD-EKQVDDGRRIKASTTTYSAVLTNKDARRTDSGTYTI 8841

Query: 468  VASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527
              S++ G    +  + V              D  S P  P K +T ++T  SVTL+W   
Sbjct: 8842 KISNKAGTDTATIRVAV-------------LDKPSAPEGPIK-VT-SITCDSVTLAWEPP 8886

Query: 528  NKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIV 587
               G + I GY +E   RE       P   R W  +   +    Y V  L  G +Y+F V
Sbjct: 8887 KDDGGADITGYILE--RRE-------PDQFR-WTRVTSTLSSPRYAVTGLKDGRSYLFRV 8936

Query: 588  RTENSHGLSGPSPVSDSVTV 607
            R  + +G S P    D++ +
Sbjct: 8937 RAVSKYGESEPLETEDAILI 8956



 Score = 76.6 bits (180), Expect = 4e-12
 Identities = 94/318 (29%), Positives = 135/318 (42%), Gaps = 40/318 (12%)

Query: 504  PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
            P  P++P    VT+ SVTLSWS     G S +  Y VE   RE         +   WV  
Sbjct: 5669 PDAPSRPDIKKVTENSVTLSWSPPESDGGSPVTSYIVE--RREP--------DRDYWVKA 5718

Query: 564  ARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSN 622
             R  +  T + V+ L P   Y F V  EN  GL G S  S SV     +   ++   V  
Sbjct: 5719 TRYPITDTTFTVQDLTPKHKYEFRVIAENKAGLGGASEASKSVI----AKPPYDVPDVPV 5774

Query: 623  STEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKT 682
              +  N  +T +  EL    P+D         I N Y +E         D   + +   T
Sbjct: 5775 DLDVTN--ITKNSAELFWNPPMDDGGSP----ITN-YVVE-------MKDKFGVRW---T 5817

Query: 683  ILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSR---VAQTLDDVPDGPPINIE 739
             L     + F++T+L+  ++YEF +    K  EG+P  S    VA+   DVPD P    E
Sbjct: 5818 SLGKPTKTSFKVTNLKTGSEYEFQVRAENKAGEGEPIQSTKPIVAKDAYDVPDAPE-KPE 5876

Query: 740  MFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTN 799
               L  T+V L WSPP        ITGY  +V   +    + + A    +H+ T+L + +
Sbjct: 5877 PSSLTETSVTLTWSPPASD-GGSQITGY--IVEKKEDFMTRWVNATRDAIHK-TTLTLND 5932

Query: 800  LTSGVSYSVQIAAETIIG 817
            L  G  Y+ ++ AE   G
Sbjct: 5933 LREGSEYTFRVIAENKAG 5950



 Score = 67.7 bits (158), Expect = 2e-09
 Identities = 91/370 (24%), Positives = 152/370 (41%), Gaps = 41/370 (11%)

Query: 495  FRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTP 554
            F A     +P  P+ P   ++T +S+TLSW      G S++ GY VE   RE+  G    
Sbjct: 7166 FTAKAQYGVPDAPSPPSVSDITPSSMTLSWEPPASDGGSTVTGYIVE--KRESPVGR--- 7220

Query: 555  RNSRGWVVIARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNS 613
                 WV + R  + +T + V  L     Y F V  EN+ G+  PS     V++   + S
Sbjct: 7221 -----WVPVNRAPIKETTFKVNDLSEDRKYEFRVSAENAAGVGKPS----EVSLPRVAKS 7271

Query: 614  LWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDN 673
             ++           N   T+ ++E   A   D  +      I N Y +E         D 
Sbjct: 7272 PYDAPSAPGRPTATNVDSTELVLEWT-APVADGGS-----PITN-YVIEAR-------DK 7317

Query: 674  ITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN---SRVAQTLDDV 730
              + +         D + F++T L+   +Y+F +I   K   G+PS+   S VA+   D 
Sbjct: 7318 FGLRWSKINRQTVTDTT-FKVTGLKPNDEYQFRVIAENKVGLGRPSDNTESIVAKPPYDT 7376

Query: 731  PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH 790
            PD P  ++++     ++  L+WSPP        +TGY   V   D   +     +N    
Sbjct: 7377 PDAPE-SVQVTGTTASSASLEWSPP-FSDGGSPVTGY--FVERKD-QYSARWTRVNRVPV 7431

Query: 791  QATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSI 850
              T++++ +L  G+ Y  ++ AE   G+G  S      +    V  D  S  P+   ++ 
Sbjct: 7432 TETNMVVGDLKEGLQYQFRVCAENRAGIGRSSDSTKPTVIKDPV--DAPSA-PLEPTIAS 7488

Query: 851  VAGDFVMETW 860
            +  D    TW
Sbjct: 7489 ITADSATLTW 7498



 Score = 66.1 bits (154), Expect = 6e-09
 Identities = 76/313 (24%), Positives = 127/313 (40%), Gaps = 28/313 (8%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQP-ATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPA 63
           +T  E P  +  PL    A     AT  C     P   + W KG   VV SD ++  + +
Sbjct: 502 LTVNEKPLEVLSPLTKLFAYLTGNATFECEVS-EPWANVTWLKGDKEVVPSDKYK--MES 558

Query: 64  GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE--PESKQSAQ 121
            G F      G    D   Y C   +     +  +A L   +LRE  ++   PE + S +
Sbjct: 559 DGRFRRMIIQGIAEDDVSDYTCVLRD-----KKTSADL---LLRETIKITKPPEDEDSRE 610

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG---NLVIQDARQTDAGRY 178
             +V   C     + + +V WKK GQ +    D R  +++ G    LVI+D   +DAG+Y
Sbjct: 611 RQSVKFVCELTGDAAKADVKWKKGGQVV--RKDKRHKIINEGLVSTLVIEDLSPSDAGKY 668

Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL---- 234
             +  N       ++  LK    P   T P+ V  Q G S  F+  + G P+P++     
Sbjct: 669 SVLVDNMEMPFTLSVQALK---PPVFTTKPKAVDTQEGMSAIFRYVIAGYPVPEIKFTKD 725

Query: 235 WRR-SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
           W+  +    ++     +   +  +    V   D G+Y   A+N  G V  +  + V   P
Sbjct: 726 WKEITPENSDVTFQFDEATQEHKVIFHEVTPKDAGKYLVIAKNESGEVKQAVSMMVTPRP 785

Query: 294 SINLSPNSVNVES 306
              L    +++++
Sbjct: 786 PEELMKRKMSLKA 798



 Score = 65.7 bits (153), Expect = 7e-09
 Identities = 122/506 (24%), Positives = 194/506 (38%), Gaps = 45/506 (8%)

Query: 112  LEPESKQSAQ-GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVI 167
            +EP    SA+ G  V LEC     +P   V W K+G  +   G  R++ +  G    + +
Sbjct: 9067 VEPLKDVSAKAGKIVTLECRI--SNPNAEVKWMKDGFQIF--GYDRVNEIKEGQRRAITL 9122

Query: 168  QDARQTDAGRYQC-IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVG 226
            ++    D G+Y C   + +     S  A   I +K Y     + VV +TG+++       
Sbjct: 9123 RNVGDRDTGKYSCECGKQSTSCWLSVTAPPTIDVKAY----KDVVVVKTGNTLRLLVPYT 9178

Query: 227  GDPLPDVLWRR-SAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSAS 284
            G P P V W R  A         ++  D+ + + + NV+  D G++S    N  G  +A 
Sbjct: 9179 GCPSPKVEWHRHDARISEDTRTHIETRDNRTQITIRNVVRGDTGKFSITLTNEAGQETAI 9238

Query: 285  GYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
              + V D P     P +  +E  +V R   + +  P      S   + T+     +R  +
Sbjct: 9239 IRVNVIDVP----GPPTGPLEITDVGRHCVSLSWEPPKDDGGSPIQSYTVEQREANRRMW 9294

Query: 345  HATAVFDGVTVLTINDTDKNDSRNTIVCSA-VNYAGSSFVRGKLTVTSDDDRPPPIITNG 403
             + + +      T++   +       VC+  +N  G   + G   V        P     
Sbjct: 9295 TSVSNYVSHVPFTVSGLSEKVEYEFRVCAENINGVGPP-LHGIEPVVIVAPYSVPTPPGK 9353

Query: 404  PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSG 463
            P    +    M       +   EP        +  I   R N +     V +DL K    
Sbjct: 9354 PEISNVQRDRM------TLTWSEPSHDGGKPIQGYIIERRENFSKQWNRVNRDLIKDT-- 9405

Query: 464  TYTCVASSRHGKYVWSGALLVDSPI-NP---NIHFFRAADVSSLPGPPTKPITHNVTDTS 519
            T+T    +    Y +  + + D+ I NP   +     A   +  P PP  PI  ++T TS
Sbjct: 9406 TFTIKGLTEGSNYEFRISAVNDTGIGNPSEVSAPPKLARSPAGRPTPPGAPIIGDITATS 9465

Query: 520  VTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIP 579
            V+LSWS  +  G S I  Y VE      L G      S  W +    VH T   V +L+ 
Sbjct: 9466 VSLSWSAPSTDGGSEITHYIVE----RRLKG------SYMW-IDRTVVHDTSCSVNNLVE 9514

Query: 580  GITYMFIVRTENSHG-LSGPSPVSDS 604
               Y F V   N+ G  S PS  S+S
Sbjct: 9515 DKEYTFRVTAVNAAGNESDPSRASES 9540



 Score = 65.3 bits (152), Expect = 1e-08
 Identities = 96/380 (25%), Positives = 161/380 (42%), Gaps = 50/380 (13%)

Query: 108 EEFRLEPESKQSA--QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN- 164
           EE++   E K +   +GDT  L C          V W K+G+ L      +  L + G  
Sbjct: 329 EEWKFTEELKPAKGFKGDTCELVC--EVNDENAIVEWVKHGKVL--KPSDKYELKEDGTK 384

Query: 165 --LVIQDARQTDAGRYQC-IARNAAGTRESAIATLKI--HIKPYLITGPEDVVAQTGSSV 219
             LVI+DA   D  RY C + +   G        +KI   +KP  IT  E  V       
Sbjct: 385 RILVIKDAVPVDGARYTCQLPKTKTGASLDVQIPVKIVGDLKPLTITERETAV------- 437

Query: 220 TFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAEN 276
              C V       V W +     ++ L + +VLD+G    LR+ N+   D  EY+C+   
Sbjct: 438 -LTCEVSNTKAA-VTWLKDGEPIDITLDKYEVLDEGRRKKLRIKNISPEDAAEYTCQLPR 495

Query: 277 SVGAVSASGYLTVYDPPSINLSPNSVNVE--SGNVARFTCTATGRPEPTMFWSVEGNRTI 334
           S    S++  LTV + P   LSP +      +GN A F C  +  P   + W ++G++ +
Sbjct: 496 S----SSTMTLTVNEKPLEVLSPLTKLFAYLTGN-ATFECEVS-EPWANVTW-LKGDKEV 548

Query: 335 IFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394
           + P   + K  +   F  + +  I + D +D   T V      +    +R  + +T    
Sbjct: 549 V-PS-DKYKMESDGRFRRMIIQGIAEDDVSDY--TCVLRDKKTSADLLLRETIKIT---- 600

Query: 395 RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---T 451
           +PP    +  S +   +K +      A    +  + W   G+ + ++ R  + N+G   T
Sbjct: 601 KPPE---DEDSRERQSVKFVCELTGDAA---KADVKWKKGGQVVRKDKRHKIINEGLVST 654

Query: 452 LVLKDLDKSDSGTYTCVASS 471
           LV++DL  SD+G Y+ +  +
Sbjct: 655 LVIEDLSPSDAGKYSVLVDN 674



 Score = 65.3 bits (152), Expect = 1e-08
 Identities = 84/325 (25%), Positives = 133/325 (40%), Gaps = 38/325 (11%)

Query: 495  FRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTP 554
            F A     +PG P+ P+  +++ TS TLSWS     G S I  Y +E+            
Sbjct: 4579 FIAKPPYDVPGAPSTPVASDISPTSATLSWSPPYSDGGSPITSYTIEM----------KD 4628

Query: 555  RNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSL 614
            R S  W      V +  + + SL     Y F V  EN  G   PSP     TV   +   
Sbjct: 4629 RFSSRWTKAKDMVTEETFQLNSLKENNEYQFRVIAENKAGPGEPSP-----TVNVTAKYE 4683

Query: 615  WEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNI 674
            ++        + R    T   VEL    P      K+   I+    ++G      P   +
Sbjct: 4684 FDTPQAPAEPDVRRTSPTS--VELSWVKPKSDGGSKIKGYIIE-KKVKG-----EPWTQV 4735

Query: 675  TIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGP 734
            T +    T+    D + F +  L +    EF +    K   G PSN+ V   +   P GP
Sbjct: 4736 TTD----TV----DGTSFTVRGLPEDEDVEFRISAVNKAGAGSPSNTVV---IAFKPPGP 4784

Query: 735  PINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATS 794
            P   E+  ++ T+V L W+PP+L   + +I GY  +V   +   ++  V IN +  +  +
Sbjct: 4785 PGTPEVSDVDKTSVTLTWTPPKLDGGSKVI-GY--IVEKREKGRDR-WVRINRSPVREVT 4840

Query: 795  LIMTNLTSGVSYSVQIAAETIIGLG 819
            + +T+L     Y  ++ AE  +G G
Sbjct: 4841 MSITDLVEKNEYEFRVIAENKVGPG 4865



 Score = 61.3 bits (142), Expect = 2e-07
 Identities = 80/310 (25%), Positives = 127/310 (40%), Gaps = 27/310 (8%)

Query: 21  VTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSD 79
           +T+   + A L C    + + A+ W K G  + ++     +L  G    LR  +     D
Sbjct: 428 LTITERETAVLTCEVSNTKA-AVTWLKDGEPIDITLDKYEVLDEGRRKKLRIKNISPE-D 485

Query: 80  AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDTVVLECLPPRGSPEP 138
           A  Y C+   S  T      TL V     E  L P +K  A        EC      P  
Sbjct: 486 AAEYTCQLPRSSSTM-----TLTVNEKPLEV-LSPLTKLFAYLTGNATFEC--EVSEPWA 537

Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
           NV W K  + ++     +M   DG    ++IQ   + D   Y C+ R+    + SA   L
Sbjct: 538 NVTWLKGDKEVVPSDKYKMES-DGRFRRMIIQGIAEDDVSDYTCVLRDK---KTSADLLL 593

Query: 197 KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRRSAGGGNMPLGRVKVLDDG 255
           +  IK  +   PED  ++   SV F C + GD    DV W++  G       R K++++G
Sbjct: 594 RETIK--ITKPPEDEDSRERQSVKFVCELTGDAAKADVKWKKG-GQVVRKDKRHKIINEG 650

Query: 256 ---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARF 312
              +L ++++  +D G+YS   +N     + S  +    PP     P +V+ + G  A F
Sbjct: 651 LVSTLVIEDLSPSDAGKYSVLVDNMEMPFTLS--VQALKPPVFTTKPKAVDTQEGMSAIF 708

Query: 313 TCTATGRPEP 322
                G P P
Sbjct: 709 RYVIAGYPVP 718



 Score = 60.9 bits (141), Expect = 2e-07
 Identities = 45/180 (25%), Positives = 79/180 (43%), Gaps = 8/180 (4%)

Query: 12    PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
             P  + +P +  VA  +  T+ C+  G P+P +RWY+ G  +       I   G +  L A
Sbjct: 9994  PQFVSKPQNAHVAEGKSVTVTCQVSGYPAPEVRWYRLGREIAHGRKFQIGGDGNIHTLTA 10053

Query: 72    THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GDTVVLE 128
                    D G      TN  GT       L+V V+  +  L    +       G+ ++L+
Sbjct: 10054 NQ-LFPEDVGEISVTVTNKGGTITDA-FELNVLVM-PKLTLPARLRTPIHLLLGEYIMLK 10110

Query: 129   CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAG 187
              +P  G+P P++ W ++G+ ++  G   +        L+I+   + DAG+Y  +A N  G
Sbjct: 10111 -VPFSGTPRPSIKWDRDGEDVVDGGRFEIKATPHDTTLIIRGITKEDAGKYSVVASNELG 10169



 Score = 59.3 bits (137), Expect = 6e-07
 Identities = 85/328 (25%), Positives = 133/328 (40%), Gaps = 45/328 (13%)

Query: 503  LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRG-WV 561
            +PGPP +P   NV  T++T+SW+     G S + GY +E               SRG WV
Sbjct: 1915 VPGPPAQPTCENVNKTTITVSWTPPEDDGGSPVTGYVIERCDV-----------SRGRWV 1963

Query: 562  VIAR-RVHQTHYVVKSLIPGITYMFIVRTENSH--GLSGPSPVSDSVTVGDDSNSLWEGT 618
               R +V +  + V  L  G  Y F +  EN+   G   P+  + +  +  D+       
Sbjct: 1964 KCNRDKVTELTFTVSDLTDGGQYQFRISAENAAGVGQPSPTSATFTAKLPFDAPG---AP 2020

Query: 619  GVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEY 678
            G    TEY    +T      I  TP +S         +  + +E           +T E 
Sbjct: 2021 GKPQVTEYNITKMT------ITWTPPESDG----GSPVTGFVVERKEKTSSRWVRVTKET 2070

Query: 679  EMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEG---KPSNSRVAQTLDDVPDGPP 735
              +T L         +T L + ++Y+F +I       G   +PS+ + A+   DVP  P 
Sbjct: 2071 VTETTL--------TVTGLTEGSEYQFRVIAENLAGPGPASEPSDLQKAKLPFDVPTAPG 2122

Query: 736  INIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSL 795
               ++   + T + L W+ PE       ITGY +          K   AI T V + T+ 
Sbjct: 2123 -KPDITSADKTEMELTWTIPESD-GGSPITGYTIEKK---EKTGKWTKAIKTVVTETTTT 2177

Query: 796  IMTNLTSGVSYSVQIAAETIIGLGPFSQ 823
            + T L     Y  ++AA  + G GPFS+
Sbjct: 2178 V-TKLIEKKEYQFRVAAINLAGTGPFSE 2204



 Score = 58.8 bits (136), Expect = 8e-07
 Identities = 90/376 (23%), Positives = 152/376 (40%), Gaps = 45/376 (11%)

Query: 444  RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSL 503
            R + N+ T+ + DL + +   +  +A ++ G            P NP+I F   A    +
Sbjct: 4145 RTLVNETTMTVSDLVEKNDYEFRVIAENKVGP---------GEPSNPSIKFVAKAPFD-V 4194

Query: 504  PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
            P  P  P   NVT T+ TL+W+   + G S I GY +E+  R           +R   V 
Sbjct: 4195 PAAPDAPEPSNVTPTTATLTWTPPKRDGGSPITGYILEMKDRFA---------TRWTQVN 4245

Query: 564  ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNS 623
               + +    +K+L  G  Y F V   N  G S PS  +++V +      +         
Sbjct: 4246 TDSMTEVTCTLKTLKEGTEYQFRVIAVNKAGQSKPS--AETVVIAKHPFDVPGAPSTPTI 4303

Query: 624  TEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTI 683
            T+      T + + L    P  +   +     +  YY+E +   +RP  +   +  +K  
Sbjct: 4304 TK-----ATPNSISLAWRPPKVNGGSR-----VTGYYIE-MKDEYRPRWSPINKVAIKD- 4351

Query: 684  LHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFIL 743
                  + +++  L K  KY F +    K  +GKPS    A T     D P I+ ++  +
Sbjct: 4352 ------TDYKVMDLTKNEKYYFRVKAENKAGQGKPSLDTKA-TAKYPFDAPTID-DVSRI 4403

Query: 744  NTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSG 803
            + T+  +KW+PP        I+GY  ++   D  A K    I  T+   TS  + NL  G
Sbjct: 4404 SETSAKIKWTPPSND-GGAEISGY--IIEKKDRLAVKWSPVIEDTLDN-TSFTVKNLREG 4459

Query: 804  VSYSVQIAAETIIGLG 819
                 +++A    G G
Sbjct: 4460 EDVEFRVSAVNKAGTG 4475



 Score = 58.8 bits (136), Expect = 8e-07
 Identities = 103/443 (23%), Positives = 166/443 (37%), Gaps = 42/443 (9%)

Query: 178  YQCIARNAAGTRE-SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV----GGDPLPD 232
            ++ +A+N AG  + S++AT  I  KP       D+   T +SVT         GG P+  
Sbjct: 5645 FRVVAKNKAGASQPSSVATFSI--KPPDAPSRPDIKKVTENSVTLSWSPPESDGGSPVTS 5702

Query: 233  VLWRRSAGGGNMPLGRVKV-LDDGSLRLDNVILADEGEYSCEAENSVGAVSAS-GYLTVY 290
             +  R     +  +   +  + D +  + ++    + E+   AEN  G   AS    +V 
Sbjct: 5703 YIVERREPDRDYWVKATRYPITDTTFTVQDLTPKHKYEFRVIAENKAGLGGASEASKSVI 5762

Query: 291  DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
              P  ++    V+++  N+ + +      P      S   N  +      +DK+      
Sbjct: 5763 AKPPYDVPDVPVDLDVTNITKNSAELFWNPPMDDGGSPITNYVVEM----KDKFGVRWTS 5818

Query: 351  DGV-TVLTINDTD-KNDSRNTIVCSAVNYAGSSF-VRGKLTVTSDDDRPPPIITNGPSNQ 407
             G  T  +   T+ K  S       A N AG    ++    + + D    P     P   
Sbjct: 5819 LGKPTKTSFKVTNLKTGSEYEFQVRAENKAGEGEPIQSTKPIVAKDAYDVPDAPEKPEPS 5878

Query: 408  TLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG----TLVLKDLDKSDS 462
            +L   S+ + +   A      I  +  E +        N T D     TL L DL +   
Sbjct: 5879 SLTETSVTLTWSPPASDGGSQITGYIVEKKEDFMTRWVNATRDAIHKTTLTLNDLREGSE 5938

Query: 463  GTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTL 522
             T+  +A ++ G+   S       P  P    F+A     +P  P  P   N+T+TS TL
Sbjct: 5939 YTFRVIAENKAGQSKPS------EPCRP----FKAKKPYGVPDTPGSPEASNITETSATL 5988

Query: 523  SWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGI 581
            +W      G S I  Y++E   RE  SG         W    R  V +T + V+ L  G 
Sbjct: 5989 NWKAPTSDGGSPITNYEIE--KREGASGR--------WTTCNRFDVSETSFTVRDLRAGH 6038

Query: 582  TYMFIVRTENSHGLSGPSPVSDS 604
             Y F V   N  G   PS  S++
Sbjct: 6039 EYSFRVAAVNKAGSGKPSVPSET 6061



 Score = 58.4 bits (135), Expect = 1e-06
 Identities = 87/331 (26%), Positives = 139/331 (41%), Gaps = 40/331 (12%)

Query: 503  LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
            LPGPP  P  +N +D SV L W+   + G + I+GY +E    E    N        WV 
Sbjct: 5372 LPGPPGTPEVYNPSDKSVDLRWTPPTEQGGTRIIGYFIE--KCEVGKDN--------WVR 5421

Query: 563  IAR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVS 621
            I R  + + +YVV  L     + F V  EN  G+  PS  S+SV +      L      S
Sbjct: 5422 INRSSIREANYVVGDLTLNCRFKFRVCAENRAGVGPPSDYSESVLI-----KLPYDVPES 5476

Query: 622  NSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMK 681
              T   +++  D +V  I   P  S     + E    Y +E    Y      +T     K
Sbjct: 5477 PDTPKISDVTNDSMV--ISWQPPYSDGGSKVTE----YIIEKKEPYSSKWVPVT-----K 5525

Query: 682  TILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGK---PSNSRVAQTLDDVPDGPPINI 738
            T     D+S ++IT L++   YEF +    K    +   P+ S  A+   DVP   P ++
Sbjct: 5526 T----RDLS-YKITGLKENGDYEFRVAAVNKAGASEFSVPTPSTKAKLPYDVP-SQPHSL 5579

Query: 739  EMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMT 798
            ++  ++ T++ L+WS P+    +  ++GY  ++   D   +     +N T    T   +T
Sbjct: 5580 KIADVSPTSLTLEWSEPDSDGGDN-VSGY--IIEKKD-RFSPRWTPVNQTAISDTKFKVT 5635

Query: 799  NLTSGVSYSVQIAAETIIGLGPFSQKVYFNI 829
             L  G     ++ A+   G    S    F+I
Sbjct: 5636 GLKDGQDCEFRVVAKNKAGASQPSSVATFSI 5666



 Score = 57.6 bits (133), Expect = 2e-06
 Identities = 52/190 (27%), Positives = 83/190 (43%), Gaps = 30/190 (15%)

Query: 424  TPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
            TP P ++W   G+ + +++R  + ++    TL  +  +++DSG Y   AS++ G+     
Sbjct: 8496 TPTPTVSWTQNGDTVQKSNRITIDSNNYGTTLTARTAERTDSGDYVIRASNKAGEDT--- 8552

Query: 481  ALLVDSPINPNIHFFRAADVSSLPGPPTKPITH-NVTDTSVTLSWSQNNKIGSSSILGYQ 539
               V   +N          V   P PP  P+    +    VTLSWS+    G S I GY 
Sbjct: 8553 ---VTVTVN----------VVDSPSPPQGPLALVKLGSNEVTLSWSRPRDDGGSPITGYV 8599

Query: 540  VEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
            +E   RE   G+        W  ++ ++  T + V  L     Y F VR EN+ G+S P 
Sbjct: 8600 LE--KREGGYGS--------WTNVSSKIPDTTFRVTKLTEDREYQFRVRAENNLGVSEPL 8649

Query: 600  PVSDSVTVGD 609
                 +  GD
Sbjct: 8650 ESERIIPKGD 8659



 Score = 56.8 bits (131), Expect = 3e-06
 Identities = 35/104 (33%), Positives = 50/104 (48%), Gaps = 11/104 (10%)

Query: 503  LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
            +PGPP+KP T N+  T++T++W+     G S + GY VE    E   G         WV 
Sbjct: 2217 VPGPPSKPTTENINKTTITITWTPPENDGGSPVTGYIVE--KCEGARGR--------WVK 2266

Query: 563  IAR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605
              +  V +    +  L  G  Y F V  EN+ G+  P P SD+V
Sbjct: 2267 CNKDLVTELTLTISDLHEGNDYQFRVSAENAAGVGQPGPPSDTV 2310



 Score = 56.4 bits (130), Expect = 4e-06
 Identities = 40/132 (30%), Positives = 67/132 (50%), Gaps = 9/132 (6%)

Query: 688  DVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTT 747
            D + F I  L++  + EF ++   K   GKPS + V   L   P GPP +  +  +  T+
Sbjct: 5038 DDTNFTIKGLKEGEEAEFRVVAVNKAGSGKPSQTTVLAAL---PPGPPESPSISDVKQTS 5094

Query: 748  VHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYS 807
            V L W+PPE    + II GY  +V   D+      V +N +  + T++++T+L     Y 
Sbjct: 5095 VTLSWTPPESDGGSKII-GY--IVEKKDM---GRWVKVNRSPVRETTMVVTDLVEKSEYE 5148

Query: 808  VQIAAETIIGLG 819
             ++ AE  +G+G
Sbjct: 5149 FRVMAENKVGVG 5160



 Score = 55.6 bits (128), Expect = 8e-06
 Identities = 84/319 (26%), Positives = 133/319 (41%), Gaps = 43/319 (13%)

Query: 507  PTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARR 566
            P+ P   N+T  S+TL+W+     G S I GY +E   RE       P  S GW V+ R 
Sbjct: 6876 PSTPDVSNITGESMTLNWTAPRTDGGSPITGYVIE--KRE-------PGRS-GWTVVNRS 6925

Query: 567  -VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTE 625
             +     VV +L  G  Y F V  EN  GL  PS V+   T    +   +   G+ +  E
Sbjct: 6926 PITSLSCVVPNLRQGAEYEFRVIAENKAGLGRPSQVTHPFT----AKPPYTTPGIPDQPE 6981

Query: 626  YRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILH 685
                      VE + AT     TI + W   +  Y  G  I    +++ + +  M+ +  
Sbjct: 6982 ----------VEDVTAT-----TITISWSPPS--YDGGSKITGYTIESKS-DATMRWVKI 7023

Query: 686  SNDVSGFEITS--LRKYTKYEFFLIPFYKKFEG---KPSNSRVAQTLDDVPDGPPINIEM 740
             + V     T+  L++ ++Y+F +    K   G   KPS     +   D P  PP   ++
Sbjct: 7024 ESTVPDTTYTAARLKELSEYQFRVAAINKAGRGDFSKPSRPVTCKPPYD-PPPPPDAPDV 7082

Query: 741  FILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNL 800
            + +  T+  L WS P  Q     ITGY  V++  D  + +  V  +      T   +  L
Sbjct: 7083 YNITPTSAALTWSTPR-QDGGSPITGY--VIDKKDKYSTR-WVKADEVPAGTTDFTIKGL 7138

Query: 801  TSGVSYSVQIAAETIIGLG 819
             +G  Y  +++A    G+G
Sbjct: 7139 QAGNDYEFRVSAVNAAGVG 7157



 Score = 55.6 bits (128), Expect = 8e-06
 Identities = 89/344 (25%), Positives = 129/344 (37%), Gaps = 49/344 (14%)

Query: 267   EGEYSCEAENSVGAV---SASGYLTVYDP-----PSINLSPNSVNVESGNVARFTCTATG 318
             E E+   AENS+GA    + S  + V DP     P     P + +V  G     TC  +G
Sbjct: 9960  EYEFRVMAENSMGASEPSTVSQRVLVRDPIDTVPPQFVSKPQNAHVAEGKSVTVTCQVSG 10019

Query: 319   RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
              P P + W   G        ++  +         +  LT N     D    I  +  N  
Sbjct: 10020 YPAPEVRWYRLGRE------IAHGRKFQIGGDGNIHTLTANQLFPEDV-GEISVTVTNKG 10072

Query: 379   GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438
             G+     +L V        P     P +  L    M   P +   TP P I W  +GE +
Sbjct: 10073 GTITDAFELNVLVMPKLTLPARLRTPIHLLLGEYIMLKVPFSG--TPRPSIKWDRDGEDV 10130

Query: 439   IQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFF 495
             +   R  +    +D TL+++ + K D+G Y+ VAS+  G    S        I  NI   
Sbjct: 10131 VDGGRFEIKATPHDTTLIIRGITKEDAGKYSVVASNELGHDTCS--------IQVNI--- 10179

Query: 496   RAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPR 555
                     P  P       +T  ++ L+W+     G S+I  Y VE   RE   G  T  
Sbjct: 10180 -----LRHPDSPRNLECLEITSEAIRLAWNPPIYDGGSNISSYMVE--KREV--GVLT-- 10228

Query: 556   NSRGWV-VIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
                 W  VI+ +   TH+ V +L     Y F V   N +G S P
Sbjct: 10229 ----WARVISSK--NTHHTVINLRSDTQYQFRVTAFNMYGASEP 10266



 Score = 54.8 bits (126), Expect = 1e-05
 Identities = 38/103 (36%), Positives = 47/103 (45%), Gaps = 13/103 (12%)

Query: 504  PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
            PGPP  P   +V  TSVTLSW+     G S I+GY VE             ++   WV +
Sbjct: 5079 PGPPESPSISDVKQTSVTLSWTPPESDGGSKIIGYIVE------------KKDMGRWVKV 5126

Query: 564  ARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605
             R  V +T  VV  L+    Y F V  EN  G+  PS  S  V
Sbjct: 5127 NRSPVRETTMVVTDLVEKSEYEFRVMAENKVGVGEPSAPSSRV 5169



 Score = 54.8 bits (126), Expect = 1e-05
 Identities = 47/166 (28%), Positives = 70/166 (42%), Gaps = 21/166 (12%)

Query: 37    GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
             G P P ++WY     +    H       G+  L    G    D G Y  E +N YG+  +
Sbjct: 10811 GMPEPKVKWYHEDRPLKPGAHYHFYEEDGVHTLEID-GTTEKDKGQYTAEISNQYGSIAT 10869

Query: 97    RNATLHVAVL---------REEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
             +   L V  L         +  F L        +G    L+C    G PEPN+ W K+ +
Sbjct: 10870 K-CRLDVNELFLTKFKDYRKPHFDLHLRDIFIVEGSAARLDC-KVTGVPEPNIRWFKDHK 10927

Query: 148   TLLFDGDSRMHLVDGG------NLVIQDARQTDAGRYQCIARNAAG 187
               +FDG  + + ++ G      +L+IQ+A   DAG Y C+A N  G
Sbjct: 10928 E-IFDG--QHYSIEFGEDDETCSLIIQEAFLQDAGTYTCLASNLLG 10970



 Score = 54.4 bits (125), Expect = 2e-05
 Identities = 72/264 (27%), Positives = 107/264 (40%), Gaps = 27/264 (10%)

Query: 349  VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408
            V  G+  L + D ++ DS  T    AVN  G   +  ++ V    DRP P    GP +  
Sbjct: 9748 VVGGIAELYVKDAEREDS-GTYTLEAVNELGRHSITARVNVL---DRPGP--PQGPISIQ 9801

Query: 409  LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLD--KSDSGTYT 466
                + A F  T            ++  ++ +++R +    GT +L +    K    T+ 
Sbjct: 9802 SITNNSATFTWTLPLDDGGAPIQRYQ-VSIRESNRTHWQPLGTSLLPNFTAKKLKDNTHY 9860

Query: 467  CVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQ 526
             +  +   +Y  S  L +   I     F    D  S PG PT     N+   SV +SW+ 
Sbjct: 9861 VLRVTAENQYGTSRPLEIREAILVKSPF----DPPSAPGRPT---ISNIQRDSVHVSWTA 9913

Query: 527  NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMF 585
             +  G SSI GY +E   R+T         S+ W+      V  T + + +L     Y F
Sbjct: 9914 PSSDGGSSITGYIIE--RRDT--------TSQRWIKANHEPVTTTSHTLINLREDTEYEF 9963

Query: 586  IVRTENSHGLSGPSPVSDSVTVGD 609
             V  ENS G S PS VS  V V D
Sbjct: 9964 RVMAENSMGASEPSTVSQRVLVRD 9987



 Score = 54.0 bits (124), Expect = 2e-05
 Identities = 81/324 (25%), Positives = 134/324 (41%), Gaps = 39/324 (12%)

Query: 504  PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
            PGPP  P   +V  TSVTL+W+     G S ++GY VE   RE        +    WV I
Sbjct: 4782 PGPPGTPEVSDVDKTSVTLTWTPPKLDGGSKVIGYIVE--KRE--------KGRDRWVRI 4831

Query: 564  ARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSN 622
             R  V +    +  L+    Y F V  EN  G   PS  S+ +     + + +E      
Sbjct: 4832 NRSPVREVTMSITDLVEKNEYEFRVIAENKVGPGEPSSPSERIV----AKAPYEVPSPPK 4887

Query: 623  STEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKT 682
            S +  +  LT   V L  + P+ +    ++      Y +E    +     N++ E+ + T
Sbjct: 4888 SLKATD--LTPISVTLNWSAPLSNGGSPIVG-----YTIEMKDKFSTRWTNVS-EHMVTT 4939

Query: 683  ILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN--SRVAQTLDDVPDGP-PINIE 739
            +          + +L++   Y+F +I   K   G+PS   S  A+   + P+ P P +IE
Sbjct: 4940 L-------SLNVPNLKEKNDYQFRVIAHNKAGPGQPSEPISVTAKFPFNAPEAPSPPSIE 4992

Query: 740  MFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTN 799
               ++ T+V L WSPP        +TGY  ++   D  + +    +   +   T+  +  
Sbjct: 4993 R--ISPTSVKLAWSPPNSD-GGDKVTGY--IIEKKDRFSGR-WTPVTKDIIDDTNFTIKG 5046

Query: 800  LTSGVSYSVQIAAETIIGLGPFSQ 823
            L  G     ++ A    G G  SQ
Sbjct: 5047 LKEGEEAEFRVVAVNKAGSGKPSQ 5070



 Score = 53.6 bits (123), Expect = 3e-05
 Identities = 79/317 (24%), Positives = 113/317 (35%), Gaps = 35/317 (11%)

Query: 503  LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
            LP  P KP   N+    +TL+WS     G S I+GYQ+E   R ++      R +     
Sbjct: 6371 LPDAPAKPDITNIDAKQITLAWSPPWSDGGSPIIGYQIEKKDRYSVRWTRATRET----- 6425

Query: 563  IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSN 622
                +H   Y ++ L  G    F V  EN  G+ GP   +    +      +    G   
Sbjct: 6426 ----IHDMQYTLRELTEGGEVEFRVAAENKAGV-GPFSETTGTVIAKSPFDVPSAPGTPK 6480

Query: 623  STEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKT 682
             ++     L      ++  TP  S       EI NF  +E    Y R    +     +KT
Sbjct: 6481 ISDITGTSL------VLTWTPPSSDG---GTEITNF-IIELRDRYGR-WTRVNRTQVLKT 6529

Query: 683  ILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFI 742
                    GF + +L +   YEF +    K   GKPS+S    T       P    E  I
Sbjct: 6530 --------GFNVMNLSEGDSYEFRVTAENKMGVGKPSDSTQKVTAKPPYSQPAAPNEPQI 6581

Query: 743  LNTT--TVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNL 800
             N T  +  L WSPP        ITGY +       P       +N      T   +  L
Sbjct: 6582 SNVTADSATLTWSPPR-DDGGSSITGYFIEKKDKFSP---RWTRVNHDAVTDTKFTVPAL 6637

Query: 801  TSGVSYSVQIAAETIIG 817
              G  Y  ++ A+   G
Sbjct: 6638 VPGEEYQFRVVAQNKAG 6654



 Score = 53.2 bits (122), Expect = 4e-05
 Identities = 35/101 (34%), Positives = 47/101 (46%), Gaps = 9/101 (8%)

Query: 503  LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
            +PGPP KP    V  TS+T++W+     G S + GY VE   R+ +S       SR   V
Sbjct: 2519 VPGPPGKPTILEVDSTSMTITWTPPETDGGSPVTGYVVE--KRDRVS-------SRWTKV 2569

Query: 563  IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
                + +  Y +  L  G  Y F V  EN  G+  PS  SD
Sbjct: 2570 KETSIEEVVYTIIDLKEGNDYQFRVSAENKAGVGKPSEPSD 2610



 Score = 52.8 bits (121), Expect = 5e-05
 Identities = 43/170 (25%), Positives = 67/170 (39%), Gaps = 14/170 (8%)

Query: 134   GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGT---- 188
             G PEP V W    + L        +  DG + L I    + D G+Y     N  G+    
Sbjct: 10811 GMPEPKVKWYHEDRPLKPGAHYHFYEEDGVHTLEIDGTTEKDKGQYTAEISNQYGSIATK 10870

Query: 189   -----RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSA 239
                   E  +   K + KP+      D+    GS+    C+V G P P++ W    +   
Sbjct: 10871 CRLDVNELFLTKFKDYRKPHFDLHLRDIFIVEGSAARLDCKVTGVPEPNIRWFKDHKEIF 10930

Query: 240   GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
              G +  +   +  +  SL +    L D G Y+C A N +G +S   Y+ V
Sbjct: 10931 DGQHYSIEFGEDDETCSLIIQEAFLQDAGTYTCLASNLLGRISCDSYVRV 10980



 Score = 52.4 bits (120), Expect = 7e-05
 Identities = 41/178 (23%), Positives = 76/178 (42%), Gaps = 16/178 (8%)

Query: 171   RQTDAGRYQCIARNAAGTRESAIATLKIHIK-------PYLITGPEDVVAQTGSSVTFQC 223
             R+     ++ +A N+ G  E +  + ++ ++       P  ++ P++     G SVT  C
Sbjct: 9956  REDTEYEFRVMAENSMGASEPSTVSQRVLVRDPIDTVPPQFVSKPQNAHVAEGKSVTVTC 10015

Query: 224   RVGGDPLPDVLWRRSAGGGNMPLGR-VKVLDDG---SLRLDNVILADEGEYSCEAENSVG 279
             +V G P P+V W R   G  +  GR  ++  DG   +L  + +   D GE S    N  G
Sbjct: 10016 QVSGYPAPEVRWYRL--GREIAHGRKFQIGGDGNIHTLTANQLFPEDVGEISVTVTNKGG 10073

Query: 280   AVSASGYLTVYDPPSINLSP---NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334
              ++ +  L V   P + L       +++  G         +G P P++ W  +G   +
Sbjct: 10074 TITDAFELNVLVMPKLTLPARLRTPIHLLLGEYIMLKVPFSGTPRPSIKWDRDGEDVV 10131



 Score = 51.2 bits (117), Expect = 2e-04
 Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 11/173 (6%)

Query: 365  DSRNTIVCSAVNYAG--SSFVRGKLTVTSDDDRP--PPIITNGPSNQTLPIKSMAVFPCT 420
            D   T   +AVN AG  S   R   +  ++   P   P I     N  +      +F C 
Sbjct: 9515 DKEYTFRVTAVNAAGNESDPSRASESFVAESQLPGAAPSILIEIQNAMVAEGQTGMFMCK 9574

Query: 421  AICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGKYV 477
               +P+P ++W   G  L+   + N+T D     +V+  +   ++G YT +A ++HG   
Sbjct: 9575 ISGSPKPKVSWMHHGRELMPGRKHNITEDNGVFKIVVFSVTDYETGMYTIIAKNKHGSVR 9634

Query: 478  WSGALLVDSPINPNIHFFR-AADVSSLPGPPTK-PITHNVTDTSVTLSWSQNN 528
             S  LL+  P  P +   R   D+S   G     P+T        T +W +++
Sbjct: 9635 SSAELLIQRP--PQLSIDRHLQDLSVRAGQEIHIPVTLTYGTPKPTFTWRRHD 9685



 Score = 51.2 bits (117), Expect = 2e-04
 Identities = 33/131 (25%), Positives = 61/131 (46%), Gaps = 7/131 (5%)

Query: 202  PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---SLR 258
            P ++   ++ +   G +  F C++ G P P V W    G   MP  +  + +D     + 
Sbjct: 9552 PSILIEIQNAMVAEGQTGMFMCKISGSPKPKVSWMHH-GRELMPGRKHNITEDNGVFKIV 9610

Query: 259  LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN--SVNVESGNVARFTCTA 316
            + +V   + G Y+  A+N  G+V +S  L +  PP +++  +   ++V +G       T 
Sbjct: 9611 VFSVTDYETGMYTIIAKNKHGSVRSSAELLIQRPPQLSIDRHLQDLSVRAGQEIHIPVTL 9670

Query: 317  T-GRPEPTMFW 326
            T G P+PT  W
Sbjct: 9671 TYGTPKPTFTW 9681



 Score = 50.4 bits (115), Expect = 3e-04
 Identities = 71/332 (21%), Positives = 127/332 (38%), Gaps = 18/332 (5%)

Query: 157   MHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT 215
             +++V G   L ++DA + D+G Y   A N  G R S  A + +  +P    GP  + + T
Sbjct: 9746  VNVVGGIAELYVKDAEREDSGTYTLEAVNELG-RHSITARVNVLDRPGPPQGPISIQSIT 9804

Query: 216   GSSVTFQCRV----GGDPLP--DVLWRRSAGGGNMPLGRVKVLDDGSLRL-DNV--ILAD 266
              +S TF   +    GG P+    V  R S      PLG   + +  + +L DN   +L  
Sbjct: 9805  NNSATFTWTLPLDDGGAPIQRYQVSIRESNRTHWQPLGTSLLPNFTAKKLKDNTHYVLRV 9864

Query: 267   EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV-ARFTCTATGRPEPTMF 325
               E        +    A    + +DPPS    P   N++  +V   +T  ++        
Sbjct: 9865  TAENQYGTSRPLEIREAILVKSPFDPPSAPGRPTISNIQRDSVHVSWTAPSSDGGSSITG 9924

Query: 326   WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385
             + +E   T     +  +  H        T++ + +  + + R  +  +++  +  S V  
Sbjct: 9925  YIIERRDTTSQRWIKAN--HEPVTTTSHTLINLREDTEYEFR-VMAENSMGASEPSTVSQ 9981

Query: 386   KLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN 445
             ++ V    D  PP   + P N  +         C     P P + WY  G  +    +  
Sbjct: 9982  RVLVRDPIDTVPPQFVSKPQNAHVAEGKSVTVTCQVSGYPAPEVRWYRLGREIAHGRKFQ 10041

Query: 446   VTNDG---TLVLKDLDKSDSGTYTCVASSRHG 474
             +  DG   TL    L   D G  +   +++ G
Sbjct: 10042 IGGDGNIHTLTANQLFPEDVGEISVTVTNKGG 10073



 Score = 50.0 bits (114), Expect = 4e-04
 Identities = 40/129 (31%), Positives = 67/129 (51%), Gaps = 7/129 (5%)

Query: 692  FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751
            F +T+++   + EF +I   K  EGKPS S V+ T   +P GPP   E++  +  +V L+
Sbjct: 5336 FTVTNVQDDAECEFHVIAINKAGEGKPSPS-VSLTFR-LP-GPPGTPEVYNPSDKSVDLR 5392

Query: 752  WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811
            W+PP  Q    II GY   +   +V    + V IN +  +  + ++ +LT    +  ++ 
Sbjct: 5393 WTPPTEQGGTRII-GY--FIEKCEV-GKDNWVRINRSSIREANYVVGDLTLNCRFKFRVC 5448

Query: 812  AETIIGLGP 820
            AE   G+GP
Sbjct: 5449 AENRAGVGP 5457



 Score = 48.8 bits (111), Expect = 9e-04
 Identities = 50/208 (24%), Positives = 81/208 (38%), Gaps = 19/208 (9%)

Query: 444  RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSL 503
            +++  D TL + DL + +   +  +A ++ G            P NP+  F   A     
Sbjct: 3171 KSLVKDTTLKVNDLTEKNQYEFRVIAENKVGP---------GEPSNPSARFTAKAPFDE- 3220

Query: 504  PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
            P  P      ++T TS TLSW   +  G S ILGY +E   R          +SR   V 
Sbjct: 3221 PEAPYSLAASDITPTSATLSWLPPDSDGGSPILGYTLETKDR---------FSSRWTKVN 3271

Query: 564  ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNS 623
               + +T + V +L     Y++ V  EN  G S PS     +           G  V+  
Sbjct: 3272 KGLLQETSFKVTNLEENNEYVYRVIAENKAGPSKPSNECKFIAKHQFETPEAPGNVVAKD 3331

Query: 624  TEYRNNILTDHIVELIEATPIDSKTIKL 651
            T   + ++T         +PI   T+++
Sbjct: 3332 TTPTSTVITWREPSFDGGSPITGYTVEM 3359



 Score = 48.8 bits (111), Expect = 9e-04
 Identities = 38/114 (33%), Positives = 47/114 (41%), Gaps = 10/114 (8%)

Query: 493  HFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNN 552
            H F A    + PG P +P   +VT T++T+SWS  +  G S I GY +E  S  T+    
Sbjct: 6963 HPFTAKPPYTTPGIPDQPEVEDVTATTITISWSPPSYDGGSKITGYTIESKSDATMR--- 7019

Query: 553  TPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVT 606
                   WV I   V  T Y    L     Y F V   N  G    S  S  VT
Sbjct: 7020 -------WVKIESTVPDTTYTAARLKELSEYQFRVAAINKAGRGDFSKPSRPVT 7066



 Score = 48.0 bits (109), Expect = 0.002
 Identities = 34/97 (35%), Positives = 44/97 (45%), Gaps = 12/97 (12%)

Query: 504  PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
            PGPP  P   +V    VTL+W+     G S+I+GY VE   RE           R W+ +
Sbjct: 4095 PGPPGMPEVSDVDKNCVTLNWTPPTSDGGSTIIGYTVE--KRE---------KGRSWIRV 4143

Query: 564  ARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
             R  V++T   V  L+    Y F V  EN  G   PS
Sbjct: 4144 NRTLVNETTMTVSDLVEKNDYEFRVIAENKVGPGEPS 4180



 Score = 48.0 bits (109), Expect = 0.002
 Identities = 73/329 (22%), Positives = 119/329 (36%), Gaps = 44/329 (13%)

Query: 495  FRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTP 554
            F+A    + P  P+ P+   VT  SV LSW      G S I+ Y VE   ++  S   T 
Sbjct: 6062 FKAQPPYAAPEAPSAPVIEEVTANSVKLSWEPPRLDGGSHIIDYVVE--KKDAFSIRWTE 6119

Query: 555  RNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSL 614
             N         R  +T + V  L  G    F V   N  G   PS    SVTV       
Sbjct: 6120 VN---------RTPETTFTVPKLKEGDAVQFRVTAVNKAGPGKPS--QSSVTV------- 6161

Query: 615  WEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNI 674
                        +             A  +D+ +I + W          +  Y   +   
Sbjct: 6162 ----------TLKPEFTVPEAPSQPTAVEVDAVSITVRWSAPKNDGGSRITNYILEMKEQ 6211

Query: 675  TIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN------SRVAQTLD 728
               +  +     +    +++T L++    EF +I   K  EGKPS+      ++   T+ 
Sbjct: 6212 FSSFWKRVSTKESSELTYQVTGLKENQTLEFRVIAVNKAGEGKPSSVGGPFTTKATYTVP 6271

Query: 729  DVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTT 788
              P  P ++     +  T++ + W+   +      ITGY  V+   DV   +  V +N  
Sbjct: 6272 SAPGAPDVS----NVKATSMTVTWT-KSISDGGSPITGY--VLEKCDVSTGR-WVPVNRV 6323

Query: 789  VHQATSLIMTNLTSGVSYSVQIAAETIIG 817
              + TSL++  L     Y  ++ A  + G
Sbjct: 6324 PLRETSLVVDQLREKSEYCFRVVAHNVAG 6352



 Score = 47.6 bits (108), Expect = 0.002
 Identities = 35/108 (32%), Positives = 55/108 (50%), Gaps = 5/108 (4%)

Query: 716  GKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLD 775
            G PS++  A+   D P G P   ++   N T + + WSPPE       +TG+  VV   +
Sbjct: 2304 GPPSDTVKAKLPFDAP-GAPGKPQVTEYNITKMTITWSPPESD-GGSPVTGF--VVERKE 2359

Query: 776  VPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQ 823
              +++ +     TV + T+LI+T LT G  Y  ++ AE   G GP S+
Sbjct: 2360 STSSRWVRVTKETVTE-TTLIVTGLTEGSEYQFRVIAENPAGPGPASE 2406



 Score = 46.8 bits (106), Expect = 0.004
 Identities = 72/267 (26%), Positives = 109/267 (40%), Gaps = 34/267 (12%)

Query: 504  PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
            P  P+KP   ++  TS  ++W+     G S + GY VE   RE        +    WV +
Sbjct: 3504 PSAPSKPEVTDIQKTSAVVTWTAPKNDGGSQVTGYTVE--KRE--------KGRDQWVRV 3553

Query: 564  ARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSN 622
             R+ V +T   V  L+    Y F V  EN  G    S  S S T     +      GV  
Sbjct: 3554 NRKPVTETTMKVPDLVEKNNYEFRVIAENRAGPGEASDASASFTAKAPFDEP-SAPGVPK 3612

Query: 623  STEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKT 682
            ++      +T   V L    P DS     + E    Y LE    Y      +T +    T
Sbjct: 3613 ASN-----ITPTSVTLSWTAP-DSDGGSPITE----YILESKDKYSSKFSPVTRD----T 3658

Query: 683  ILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSR--VAQTLDDVPDGPPINIEM 740
            +    D++ F + +L++  +Y+F +I   K    +PS     VA+   +VP  P    E+
Sbjct: 3659 V---TDLT-FTVKNLKENGEYQFRVIAQNKAGPSEPSRETKVVAKYEFEVPQAPSAP-EV 3713

Query: 741  FILNTTTVHLKWSPPELQLQNGIITGY 767
              L+ T++ L W+PP        ITGY
Sbjct: 3714 RRLSPTSIQLDWTPPFAD-GGSDITGY 3739



 Score = 46.8 bits (106), Expect = 0.004
 Identities = 32/104 (30%), Positives = 48/104 (46%), Gaps = 11/104 (10%)

Query: 503  LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV- 561
            +P PP +P   N+T  SVTL+W+  +  G S + GY VE             R S  WV 
Sbjct: 7775 VPSPPGEPTISNITAKSVTLNWTPPSSDGGSPVTGYTVE----------RADRFSTRWVP 7824

Query: 562  VIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605
            V +  +  T   +  L    +Y F +   N+ G S P+  +DS+
Sbjct: 7825 VNSHPIKDTKMDIHDLPATGSYQFRIVACNAAGTSKPTSPTDSI 7868



 Score = 46.8 bits (106), Expect = 0.004
 Identities = 45/162 (27%), Positives = 68/162 (41%), Gaps = 10/162 (6%)

Query: 112  LEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQD 169
            +E ++   A+G T +  C    GSP+P V W  +G+ L+  G       D G   +V+  
Sbjct: 9556 IEIQNAMVAEGQTGMFMC-KISGSPKPKVSWMHHGRELM-PGRKHNITEDNGVFKIVVFS 9613

Query: 170  ARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP--EDVVAQTGSSVTFQCRVG- 226
                + G Y  IA+N  G+  S+ A L I   P L      +D+  + G  +     +  
Sbjct: 9614 VTDYETGMYTIIAKNKHGSVRSS-AELLIQRPPQLSIDRHLQDLSVRAGQEIHIPVTLTY 9672

Query: 227  GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268
            G P P   WRR  G      GR    + G  R+ +  L D G
Sbjct: 9673 GTPKPTFTWRRHDGEELDTRGRYSTKEQG--RVHDFELPDLG 9712



 Score = 46.4 bits (105), Expect = 0.005
 Identities = 36/129 (27%), Positives = 63/129 (48%), Gaps = 8/129 (6%)

Query: 694  ITSLRKYTKYEFFLIPFYKKFEG---KPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHL 750
            +T L +  +Y+F +        G   +PS++++A+   DVP GPP       +N TT+ +
Sbjct: 2178 VTKLIEKKEYQFRVAAINLAGTGPFSEPSDNKMAKAPYDVP-GPPSKPTTENINKTTITI 2236

Query: 751  KWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQI 810
             W+PPE       +TGY  +V   +  A    V  N  +    +L +++L  G  Y  ++
Sbjct: 2237 TWTPPEND-GGSPVTGY--IVEKCE-GARGRWVKCNKDLVTELTLTISDLHEGNDYQFRV 2292

Query: 811  AAETIIGLG 819
            +AE   G+G
Sbjct: 2293 SAENAAGVG 2301



 Score = 46.4 bits (105), Expect = 0.005
 Identities = 41/140 (29%), Positives = 63/140 (45%), Gaps = 7/140 (5%)

Query: 688  DVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTT 747
            D + F + +LR+    EF +    K   GKPS+     TL   P GPP   E   ++  +
Sbjct: 4447 DNTSFTVKNLREGEDVEFRVSAVNKAGTGKPSS---IATLAAKPPGPPGVPEASNIDKIS 4503

Query: 748  VHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYS 807
              L W+PPE       +TGY  +V   +   ++ M  +N    +  +L + +LT    Y 
Sbjct: 4504 ATLTWTPPESD-GGSKVTGY--IVEKRERGLDRWM-KVNRAPVKDVTLKVLDLTEKKHYE 4559

Query: 808  VQIAAETIIGLGPFSQKVYF 827
             ++ AE   GLG  S  V F
Sbjct: 4560 FRVTAENKAGLGEPSDSVSF 4579



 Score = 46.0 bits (104), Expect = 0.006
 Identities = 33/102 (32%), Positives = 45/102 (44%), Gaps = 9/102 (8%)

Query: 505  GPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIA 564
            G P+ P+  + T TSVTL W+     G S I GY +E   +E  S    P  S+      
Sbjct: 7676 GRPSPPVVTDFTKTSVTLQWNPPESDGGSHITGYVLE--KKEAYSVRWFPCTSQS----- 7728

Query: 565  RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVT 606
              + +  + VK L  G  Y F V   N  G+  PS  S+  T
Sbjct: 7729 --ILKPEFTVKDLKEGAQYEFRVMALNKAGIGPPSDGSELAT 7768



 Score = 45.6 bits (103), Expect = 0.008
 Identities = 35/107 (32%), Positives = 46/107 (42%), Gaps = 11/107 (10%)

Query: 495  FRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTP 554
            F A     +P  P KP   +++ TSVTL+W+     G S I GY VE+            
Sbjct: 2916 FVAKPPYDVPDAPGKPAPSDLSPTSVTLTWTPPPSDGGSPITGYTVEM----------KD 2965

Query: 555  RNSRGWVVIARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600
            + S  W    R  + +T  V+  L     Y F V  EN  G S PSP
Sbjct: 2966 KFSTRWTKATRELISETTVVLPDLKEKEEYQFRVIAENKAGQSKPSP 3012



 Score = 45.6 bits (103), Expect = 0.008
 Identities = 33/99 (33%), Positives = 43/99 (43%), Gaps = 10/99 (10%)

Query: 504  PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
            P PPT P    ++ TSV L+WS     G S +  Y VE   ++  SG  TP       V 
Sbjct: 3409 PKPPTPPEVKRLSPTSVQLNWSAPTSDGGSEVTAYIVE---KKDKSGRWTP-------VT 3458

Query: 564  ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602
            +  +  T + VK L  G    F V   N  G   PS V+
Sbjct: 3459 SDSIEDTSFTVKGLKEGEDVEFRVSAVNKAGTGKPSEVT 3497



 Score = 45.6 bits (103), Expect = 0.008
 Identities = 40/134 (29%), Positives = 64/134 (47%), Gaps = 8/134 (5%)

Query: 693  EITSLRKYTKYEFFLIPFYKKFEGKPSNS---RVAQTLDDVPDGPPINIEMFILNTTTVH 749
            +I+ L++  +Y+F ++   K  +  PSN    +VA++  DVP+ P    ++  +  T+V 
Sbjct: 7536 KISGLKEGNEYQFRVVATNKAGQSAPSNPSQPKVAKSPYDVPEAPS-KPQVTEVKATSVT 7594

Query: 750  LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQ 809
            LKW PP        ITGY  VV   +  A +    +NTT    T   +T LT    Y  +
Sbjct: 7595 LKWRPPGSD-GGSPITGY--VVQKKERLALR-WTPVNTTPVGDTIFTVTGLTQKSEYEFR 7650

Query: 810  IAAETIIGLGPFSQ 823
            + A    G G  S+
Sbjct: 7651 VVAANKKGFGQPSE 7664



 Score = 45.6 bits (103), Expect = 0.008
 Identities = 88/401 (21%), Positives = 150/401 (37%), Gaps = 52/401 (12%)

Query: 226  GGDPLPDVLWRRSAGGGNMPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVG---A 280
            GG P+   +  +     N    +V  +  G  S R+  ++  +E E+   AEN  G   A
Sbjct: 8097 GGAPISGYIIEKKETSSNY-WSKVTTVSSGVTSHRIPRLMRGEEYEFRVSAENRAGPGPA 8155

Query: 281  VSASGYLTVYD----PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF 336
             + S  +   D    P         +  + G   R     TG P P + WS +G      
Sbjct: 8156 STPSAPIRAEDTTVLPKFSGRFDEPIMAKVGESFRIEVPYTGIPTPAVTWSFDGRP---- 8211

Query: 337  PGMSRDKYHATAVFDGVTVLTINDTDK-NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395
              +    +      +  + +T+ + +K N  R TI  +  N AG+  +  ++ V    DR
Sbjct: 8212 --LKPSAHIRIDTSNRASTITVKNVEKANGGRYTI--NLKNTAGAESLDVEVRVF---DR 8264

Query: 396  PPPIITNGPSNQTLPIKSMAVFPCTAICTP--EPIIAWYFEGEALIQNHRRNVTNDG--- 450
            P P    GP   +   +S      +         I  +  +    I+   ++V  D    
Sbjct: 8265 PGP--PRGPLEMSNVSESTVTLSWSPPSDDGGSRIFTYVVQKRGEIETKWKHVNKDYIID 8322

Query: 451  -TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTK 509
             T  +  L ++    +  +A +++G+       L    I P   +       ++P PP+ 
Sbjct: 8323 LTYKVTGLKENKKYQFRVLAENQYGQ----SKPLEGQSITPQGQY-------NVPDPPSA 8371

Query: 510  PITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV-VIARRVH 568
            P   N+   SVT+ W+  +  G + + GY VE+  R+T S    PR    W+        
Sbjct: 8372 PKVTNIIGDSVTVGWTPPSNDGGAPVTGYVVEM--RQTTS----PR----WIKATLTPTP 8421

Query: 569  QTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
               +    LI G  Y F V   N  G   P   S++V V D
Sbjct: 8422 DMTFRASRLIRGTEYEFRVCAVNRAGTGRPGEPSNTVMVED 8462



 Score = 45.2 bits (102), Expect = 0.011
 Identities = 37/146 (25%), Positives = 64/146 (43%), Gaps = 9/146 (6%)

Query: 683  ILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFI 742
            +  S D + F +  L++    EF +    K  + KPS   +       P GPP   E+  
Sbjct: 4049 VTDSVDGTSFTVKGLKEGENVEFRVSAVNKAGQSKPSEVSLVAVK---PPGPPGMPEVSD 4105

Query: 743  LNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTS 802
            ++   V L W+PP     + II GY V          +S + +N T+   T++ +++L  
Sbjct: 4106 VDKNCVTLNWTPPTSDGGSTII-GYTVEKR----EKGRSWIRVNRTLVNETTMTVSDLVE 4160

Query: 803  GVSYSVQIAAETIIGLG-PFSQKVYF 827
               Y  ++ AE  +G G P +  + F
Sbjct: 4161 KNDYEFRVIAENKVGPGEPSNPSIKF 4186



 Score = 44.8 bits (101), Expect = 0.015
 Identities = 37/133 (27%), Positives = 67/133 (50%), Gaps = 8/133 (6%)

Query: 694  ITSLRKYTKYEFFLIPFYKKFEG---KPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHL 750
            I SL +  +YEF +        G   +PS+ ++A+   DVP GPP    +  +++T++ +
Sbjct: 2480 IKSLIEKKEYEFRVAAVNLAGTGPFSEPSDYQIAKAPYDVP-GPPGKPTILEVDSTSMTI 2538

Query: 751  KWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQI 810
             W+PPE       +TGY  VV   D  +++      T++ +    I+ +L  G  Y  ++
Sbjct: 2539 TWTPPETD-GGSPVTGY--VVEKRDRVSSRWTKVKETSIEEVVYTII-DLKEGNDYQFRV 2594

Query: 811  AAETIIGLGPFSQ 823
            +AE   G+G  S+
Sbjct: 2595 SAENKAGVGKPSE 2607



 Score = 44.8 bits (101), Expect = 0.015
 Identities = 36/105 (34%), Positives = 45/105 (42%), Gaps = 9/105 (8%)

Query: 503  LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
            +P  P+KP    V  TSVTL W      G S I GY V+   +E L+   TP N+     
Sbjct: 7576 VPEAPSKPQVTEVKATSVTLKWRPPGSDGGSPITGYVVQ--KKERLALRWTPVNT----- 7628

Query: 563  IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
                V  T + V  L     Y F V   N  G   PS  ++SV V
Sbjct: 7629 --TPVGDTIFTVTGLTQKSEYEFRVVAANKKGFGQPSEPTNSVLV 7671



 Score = 44.8 bits (101), Expect = 0.015
 Identities = 30/137 (21%), Positives = 53/137 (38%), Gaps = 1/137 (0%)

Query: 9    GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
            G AP I+ +  +  VA  Q     C+  GSP P + W   G  ++     +I    G+F 
Sbjct: 9549 GAAPSILIEIQNAMVAEGQTGMFMCKISGSPKPKVSWMHHGRELMPGRKHNITEDNGVFK 9608

Query: 69   LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
            +         + G+Y   A N +G+ RS    L     +       +      G  + + 
Sbjct: 9609 I-VVFSVTDYETGMYTIIAKNKHGSVRSSAELLIQRPPQLSIDRHLQDLSVRAGQEIHIP 9667

Query: 129  CLPPRGSPEPNVYWKKN 145
                 G+P+P   W+++
Sbjct: 9668 VTLTYGTPKPTFTWRRH 9684



 Score = 44.4 bits (100), Expect = 0.019
 Identities = 45/159 (28%), Positives = 63/159 (39%), Gaps = 19/159 (11%)

Query: 450  GTLVLKDLDKSDSGTYTCVASSRHGKYVW----SGALLVDSPINPNIHFFRAADVSSLPG 505
            G  V  + DK    T+T    +  G+Y +      A  V  P +P    F A      PG
Sbjct: 1960 GRWVKCNRDKVTELTFTVSDLTDGGQYQFRISAENAAGVGQP-SPTSATFTAKLPFDAPG 2018

Query: 506  PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565
             P KP       T +T++W+     G S + G+ VE             + S  WV + +
Sbjct: 2019 APGKPQVTEYNITKMTITWTPPESDGGSPVTGFVVE----------RKEKTSSRWVRVTK 2068

Query: 566  R-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
              V +T   V  L  G  Y F V  EN   L+GP P S+
Sbjct: 2069 ETVTETTLTVTGLTEGSEYQFRVIAEN---LAGPGPASE 2104



 Score = 44.4 bits (100), Expect = 0.019
 Identities = 31/104 (29%), Positives = 43/104 (41%), Gaps = 11/104 (10%)

Query: 504  PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
            P PP  P  +N+T TS  L+WS   + G S I GY ++             + S  WV  
Sbjct: 7074 PPPPDAPDVYNITPTSAALTWSTPRQDGGSPITGYVID----------KKDKYSTRWVKA 7123

Query: 564  AR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVT 606
                   T + +K L  G  Y F V   N+ G+  PS   +  T
Sbjct: 7124 DEVPAGTTDFTIKGLQAGNDYEFRVSAVNAAGVGKPSAPCERFT 7167



 Score = 44.0 bits (99), Expect = 0.025
 Identities = 45/194 (23%), Positives = 75/194 (38%), Gaps = 14/194 (7%)

Query: 109   EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ 168
             +F  +P++   A+G +V + C    G P P V W + G+ +      +  +   GN+   
Sbjct: 9995  QFVSKPQNAHVAEGKSVTVTC-QVSGYPAPEVRWYRLGREIAHG--RKFQIGGDGNIHTL 10051

Query: 169   DARQT---DAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE---DVVAQTGSSVTFQ 222
              A Q    D G       N  GT   A   L + + P L         +    G  +  +
Sbjct: 10052 TANQLFPEDVGEISVTVTNKGGTITDAFE-LNVLVMPKLTLPARLRTPIHLLLGEYIMLK 10110

Query: 223   CRVGGDPLPDVLWRRSAGGGNMPLGRVKVL---DDGSLRLDNVILADEGEYSCEAENSVG 279
                 G P P + W R  G   +  GR ++     D +L +  +   D G+YS  A N +G
Sbjct: 10111 VPFSGTPRPSIKWDRD-GEDVVDGGRFEIKATPHDTTLIIRGITKEDAGKYSVVASNELG 10169

Query: 280   AVSASGYLTVYDPP 293
               + S  + +   P
Sbjct: 10170 HDTCSIQVNILRHP 10183



 Score = 43.6 bits (98), Expect = 0.034
 Identities = 32/101 (31%), Positives = 45/101 (44%), Gaps = 14/101 (13%)

Query: 504  PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
            PG P KP       T +T++WS     G S + G+ VE   +E+ S          WV +
Sbjct: 2319 PGAPGKPQVTEYNITKMTITWSPPESDGGSPVTGFVVE--RKESTSSR--------WVRV 2368

Query: 564  ARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
             +  V +T  +V  L  G  Y F V  EN    +GP P S+
Sbjct: 2369 TKETVTETTLIVTGLTEGSEYQFRVIAENP---AGPGPASE 2406



 Score = 43.6 bits (98), Expect = 0.034
 Identities = 41/159 (25%), Positives = 65/159 (40%), Gaps = 21/159 (13%)

Query: 444  RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSL 503
            R + ++ T+VL DL + +   +  +A ++ G+          S  +P +H        + 
Sbjct: 2976 RELISETTVVLPDLKEKEEYQFRVIAENKAGQ----------SKPSPELHVTAKYPFETP 3025

Query: 504  PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
              P    +T   + TS T+ WS     G S I GY +E   +E +S    PR    W  +
Sbjct: 3026 QAPTIDNVTRE-SPTSATVKWSPPKSDGGSEITGYVLE--KKEKMS----PR----WSPV 3074

Query: 564  ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602
                 +T + VK L  G    F V   N  G   PS V+
Sbjct: 3075 IESETETSFTVKGLPDGENVEFRVSAVNKAGTGKPSQVA 3113



 Score = 43.6 bits (98), Expect = 0.034
 Identities = 77/322 (23%), Positives = 123/322 (38%), Gaps = 35/322 (10%)

Query: 499  DVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558
            D    P  P +P   ++T  S TL+W   ++ G S++ GY VE            P  +R
Sbjct: 7473 DPVDAPSAPLEPTIASITADSATLTWIAPSRDGGSAVTGYIVE---------RKDPYTAR 7523

Query: 559  GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGT 618
             W  I  R   T+  +  L  G  Y F V   N  G S PS  S    V      + E  
Sbjct: 7524 -WTPI-ERCTDTNCKISGLKEGNEYQFRVVATNKAGQSAPSNPSQP-KVAKSPYDVPEAP 7580

Query: 619  GVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEY 678
                 TE +   +T     L    P       +   ++     E L + + P++   +  
Sbjct: 7581 SKPQVTEVKATSVT-----LKWRPPGSDGGSPITGYVVQ--KKERLALRWTPVNTTPVGD 7633

Query: 679  EMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINI 738
             + T      V+G  +T   +Y   EF ++   KK  G+PS       L   P G P   
Sbjct: 7634 TIFT------VTG--LTQKSEY---EFRVVAANKKGFGQPSEP-TNSVLVKPPYGRPSPP 7681

Query: 739  EMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMT 798
             +     T+V L+W+PPE       ITGY  V+   +  + +     + ++ +     + 
Sbjct: 7682 VVTDFTKTSVTLQWNPPESD-GGSHITGY--VLEKKEAYSVRWFPCTSQSILK-PEFTVK 7737

Query: 799  NLTSGVSYSVQIAAETIIGLGP 820
            +L  G  Y  ++ A    G+GP
Sbjct: 7738 DLKEGAQYEFRVMALNKAGIGP 7759



 Score = 43.2 bits (97), Expect = 0.044
 Identities = 31/100 (31%), Positives = 42/100 (42%), Gaps = 11/100 (11%)

Query: 503  LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
            +P  P+ P    ++ TSV LSW+     G + I GY   +  ++  SG         W  
Sbjct: 4000 IPQEPSAPEVKRLSPTSVELSWTPPRSDGGADITGY---ILEKKDKSGR--------WTP 4048

Query: 563  IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602
            +   V  T + VK L  G    F V   N  G S PS VS
Sbjct: 4049 VTDSVDGTSFTVKGLKEGENVEFRVSAVNKAGQSKPSEVS 4088



 Score = 42.7 bits (96), Expect = 0.059
 Identities = 36/117 (30%), Positives = 55/117 (47%), Gaps = 10/117 (8%)

Query: 503  LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
            +P  P+KP+  NVT  SVTL W      G + I GY +E   +ET S N   + +     
Sbjct: 8069 VPEAPSKPLVTNVTSDSVTLEWHSPKSDGGAPISGYIIE--KKET-SSNYWSKVT----T 8121

Query: 563  IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTG 619
            ++  V  T + +  L+ G  Y F V  EN  G  GP+    +    +D+  L + +G
Sbjct: 8122 VSSGV--TSHRIPRLMRGEEYEFRVSAENRAG-PGPASTPSAPIRAEDTTVLPKFSG 8175



 Score = 42.7 bits (96), Expect = 0.059
 Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 12/86 (13%)

Query: 253   DDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV----------YDPPSINLSPN 300
             +DG  +L +D     D+G+Y+ E  N  G+++    L V          Y  P  +L   
Sbjct: 10837 EDGVHTLEIDGTTEKDKGQYTAEISNQYGSIATKCRLDVNELFLTKFKDYRKPHFDLHLR 10896

Query: 301   SVNVESGNVARFTCTATGRPEPTMFW 326
              + +  G+ AR  C  TG PEP + W
Sbjct: 10897 DIFIVEGSAARLDCKVTGVPEPNIRW 10922



 Score = 42.3 bits (95), Expect = 0.078
 Identities = 44/170 (25%), Positives = 78/170 (45%), Gaps = 11/170 (6%)

Query: 694  ITSLRKYTKYEFFLIPFYKKFEGKPSN---SRVAQTLDDVPDGPPINIEMFILNTTTVHL 750
            +  LR+ ++Y F ++      E KPS    + +A+    +PD P    ++  ++   + L
Sbjct: 6332 VDQLREKSEYCFRVVAHNVAGESKPSEPSKAYIAKPPYGLPDAPA-KPDITNIDAKQITL 6390

Query: 751  KWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQI 810
             WSPP     + II GY +     D  + +   A   T+H      +  LT G     ++
Sbjct: 6391 AWSPPWSDGGSPII-GYQIEKK--DRYSVRWTRATRETIHDM-QYTLRELTEGGEVEFRV 6446

Query: 811  AAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETW 860
            AAE   G+GPFS+     + ++S   D+ S  P   ++S + G  ++ TW
Sbjct: 6447 AAENKAGVGPFSETT-GTVIAKS-PFDVPSA-PGTPKISDITGTSLVLTW 6493



 Score = 41.1 bits (92), Expect = 0.18
 Identities = 78/350 (22%), Positives = 133/350 (38%), Gaps = 37/350 (10%)

Query: 128  ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNA 185
            EC   R   + ++ W K+GQ +  D   ++   DG   +L IQD    D+G+Y     + 
Sbjct: 1013 ECDVSRDVKDEDIVWMKDGQKITPDEKFQVKR-DGRRLSLSIQDTSPEDSGQYTIKIGDK 1071

Query: 186  AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
              T +  +   +  +KP   T      A+   ++  +C +  + +P   ++        P
Sbjct: 1072 TQTADLKVQAAEF-VKPLNNTS----AAEYDETIVLECELSNELVPCQWYKDDVLITVGP 1126

Query: 246  LGRVKVLDDGSLR---LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
              +V+V+DDG  R   L +V   D G + C     VG   +S  L V     +       
Sbjct: 1127 --KVEVIDDGKKRKLVLHDVRPEDTGNFRC----VVGDKESSATLDVKASEIMKPLAEVT 1180

Query: 303  NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG-VTVLTINDT 361
              E    A   C  +  P+    W  +G + I    ++  KY    V DG    L I+D 
Sbjct: 1181 APEFAETAVLECEVS-HPKAEATWLKDG-QPITPEELTSKKYE--VVSDGRKRRLIIHDV 1236

Query: 362  DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
             K+D+     C   +    + V  K+          P IT    + T   ++  V  C  
Sbjct: 1237 VKDDNAE-FTCKVGDNQTVANVNVKV----------PSITKPLEDTTTAFETTVVLECEV 1285

Query: 422  ICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCV 468
                 P + W   G+ + +  +  + + G    L + +    D G YTCV
Sbjct: 1286 DNEKAP-VKWMKNGKEITKMPKYLMESKGKKRRLTIFETIPEDEGDYTCV 1334



 Score = 41.1 bits (92), Expect = 0.18
 Identities = 37/134 (27%), Positives = 61/134 (45%), Gaps = 7/134 (5%)

Query: 692  FEITSLRKYTKYEFFLIPFYKKFEGKPS---NSRVAQTLDDVPDGPPINIEMFILNTTTV 748
            + I  L++   Y+F +    K   GKPS   + R A+   DVP GPP   ++  ++   +
Sbjct: 2579 YTIIDLKEGNDYQFRVSAENKAGVGKPSEPSDQRRAKPPYDVP-GPPGIPDISDVDKNRM 2637

Query: 749  HLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSV 808
             L W+PP        I GY  +V   D    +   A    +    +L + +LT G +Y  
Sbjct: 2638 TLTWTPPTDD-GGAKILGY--IVEKCDADRKRWTKAHKEDLVTELTLTVYDLTEGTNYMF 2694

Query: 809  QIAAETIIGLGPFS 822
            +++AE   G+G  S
Sbjct: 2695 RVSAENAAGVGESS 2708



 Score = 41.1 bits (92), Expect = 0.18
 Identities = 33/97 (34%), Positives = 39/97 (40%), Gaps = 11/97 (11%)

Query: 504  PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
            PGPP  P   N+   S TL+W+     G S + GY VE   RE        R    W+ +
Sbjct: 4488 PGPPGVPEASNIDKISATLTWTPPESDGGSKVTGYIVE--KRE--------RGLDRWMKV 4537

Query: 564  ARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
             R  V      V  L     Y F V  EN  GL  PS
Sbjct: 4538 NRAPVKDVTLKVLDLTEKKHYEFRVTAENKAGLGEPS 4574



 Score = 41.1 bits (92), Expect = 0.18
 Identities = 34/143 (23%), Positives = 63/143 (44%), Gaps = 8/143 (5%)

Query: 158  HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT--LKIHIKPYLITGP--EDVVA 213
            H +    + I D   T + +++ +A NAAGT +    T  + + + P L T    + +V 
Sbjct: 7828 HPIKDTKMDIHDLPATGSYQFRIVACNAAGTSKPTSPTDSIGMAVAPKLDTYKYHDTMVV 7887

Query: 214  QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LD-DGSLRLDNVILADEGEY 270
            + G++          P P V W +  G       R+K+   D D  + + N +  DEG +
Sbjct: 7888 RVGATFNLDVPFKATPKPTVKWTKD-GSTLQASSRIKIDTTDRDTIVTIKNCVREDEGSF 7946

Query: 271  SCEAENSVGAVSASGYLTVYDPP 293
              +  N+ G+ + +  + V D P
Sbjct: 7947 KLDVSNTAGSDAITIRVQVLDRP 7969



 Score = 41.1 bits (92), Expect = 0.18
 Identities = 44/168 (26%), Positives = 68/168 (40%), Gaps = 17/168 (10%)

Query: 318   GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
             G PEP + W  E     + PG     Y      DGV  L I+ T + D +        N 
Sbjct: 10811 GMPEPKVKWYHEDRP--LKPGAHYHFYEE----DGVHTLEIDGTTEKD-KGQYTAEISNQ 10863

Query: 378   AGSSFVRGKLTV-----TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
              GS   + +L V     T   D   P       +  +   S A   C     PEP I W+
Sbjct: 10864 YGSIATKCRLDVNELFLTKFKDYRKPHFDLHLRDIFIVEGSAARLDCKVTGVPEPNIRWF 10923

Query: 433   FEGEALIQNHRRNVT---NDGT--LVLKDLDKSDSGTYTCVASSRHGK 475
              + + +      ++    +D T  L++++    D+GTYTC+AS+  G+
Sbjct: 10924 KDHKEIFDGQHYSIEFGEDDETCSLIIQEAFLQDAGTYTCLASNLLGR 10971



 Score = 40.7 bits (91), Expect = 0.24
 Identities = 36/137 (26%), Positives = 59/137 (43%), Gaps = 7/137 (5%)

Query: 683  ILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFI 742
            ++ S   + F +  L      EF +    K   GKPS  +VA TL   P G P   E+  
Sbjct: 3074 VIESETETSFTVKGLPDGENVEFRVSAVNKAGTGKPS--QVA-TLSAKPPGAPDAPEVSD 3130

Query: 743  LNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTS 802
            ++ T+  + W+ P L      ITGY +               +N ++ + T+L + +LT 
Sbjct: 3131 IDRTSATVIWTVPSLD-GGSTITGYTIERR---EKGRDRWTRVNKSLVKDTTLKVNDLTE 3186

Query: 803  GVSYSVQIAAETIIGLG 819
               Y  ++ AE  +G G
Sbjct: 3187 KNQYEFRVIAENKVGPG 3203



 Score = 40.7 bits (91), Expect = 0.24
 Identities = 31/100 (31%), Positives = 44/100 (44%), Gaps = 11/100 (11%)

Query: 504  PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
            PG P +P   ++  TS T++W  ++  G S+I GY VE   RE        +    WV +
Sbjct: 3800 PGAPGRPEVSDINKTSATVTWKPSSSDGGSTITGYIVE--KRE--------KGRDRWVPV 3849

Query: 564  ARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602
             R+ ++     V  L     Y F V  EN  G   PS  S
Sbjct: 3850 NRKPINAVTMKVTDLTEKTDYEFRVIAENRIGQGQPSEPS 3889



 Score = 40.7 bits (91), Expect = 0.24
 Identities = 39/136 (28%), Positives = 58/136 (42%), Gaps = 15/136 (11%)

Query: 694  ITSLRKYTKYEFFLIPFYKKFEGKPSN------SRVAQTLDDVPDGPPINIEMFILNTTT 747
            + +LR+  +YEF +I   K   G+PS       ++   T   +PD P    E+  +  TT
Sbjct: 6934 VPNLRQGAEYEFRVIAENKAGLGRPSQVTHPFTAKPPYTTPGIPDQP----EVEDVTATT 6989

Query: 748  VHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYS 807
            + + WSPP        ITGY +        A    V I +TV   T+     L     Y 
Sbjct: 6990 ITISWSPPSYD-GGSKITGYTIESK---SDATMRWVKIESTVPD-TTYTAARLKELSEYQ 7044

Query: 808  VQIAAETIIGLGPFSQ 823
             ++AA    G G FS+
Sbjct: 7045 FRVAAINKAGRGDFSK 7060



 Score = 40.7 bits (91), Expect = 0.24
 Identities = 31/99 (31%), Positives = 43/99 (43%), Gaps = 9/99 (9%)

Query: 504  PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
            P  P  P   NV D S+TLSW   +  G + I  Y +E+  +ET       R +R     
Sbjct: 8963 PPAPGVPKASNVRDDSITLSWQPPHSDGGAEIHNYILEI--KET-------RGTRWLRAT 9013

Query: 564  ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602
             +++   ++ V  L  G  Y F V  EN  GL   S  S
Sbjct: 9014 RKQLKSPNFRVTGLSKGREYEFRVAAENEAGLGAFSKTS 9052



 Score = 40.3 bits (90), Expect = 0.31
 Identities = 30/103 (29%), Positives = 43/103 (41%), Gaps = 11/103 (10%)

Query: 504  PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
            PGPP  P   +V  TS+ L+WS  +  G S + GY         L   +  RN   W  +
Sbjct: 2723 PGPPPPPTPTHVDRTSIHLTWSPPDDDGGSEVTGY--------ILEKRDKARNK--WTKV 2772

Query: 564  ARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605
             +  + +  + V  L     Y F V   N  G   PS  SD++
Sbjct: 2773 NKEPIPEISFTVTGLTEDAIYDFRVSAVNKAGEGPPSLPSDTL 2815



 Score = 40.3 bits (90), Expect = 0.31
 Identities = 40/144 (27%), Positives = 61/144 (42%), Gaps = 9/144 (6%)

Query: 682  TILHSNDVSG--FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIE 739
            T + S+ V G  F +  L      EF +    K  + KPS   V   L   P G P   E
Sbjct: 3751 TPVSSDSVDGTTFTVKGLPDDEDVEFRISAVNKAGQSKPSQVTV---LTAKPPGAPGRPE 3807

Query: 740  MFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTN 799
            +  +N T+  + W P         ITGY  +V   +   ++  V +N     A ++ +T+
Sbjct: 3808 VSDINKTSATVTWKPSSSD-GGSTITGY--IVEKREKGRDR-WVPVNRKPINAVTMKVTD 3863

Query: 800  LTSGVSYSVQIAAETIIGLGPFSQ 823
            LT    Y  ++ AE  IG G  S+
Sbjct: 3864 LTEKTDYEFRVIAENRIGQGQPSE 3887



 Score = 40.3 bits (90), Expect = 0.31
 Identities = 27/78 (34%), Positives = 41/78 (52%), Gaps = 4/78 (5%)

Query: 692  FEITSLRKYTKYEFFLIPFYKKFEGKPSNSR--VAQTLDDVPDGPPINIEMFILNTTTVH 749
            F++T L+  T+Y F +I   K+ + +PS     VA+   D+P  P    E+  L+ T+V 
Sbjct: 3960 FKVTGLKDKTEYTFRIIAENKEGQSEPSKETVVVAKYGFDIPQEPSAP-EVKRLSPTSVE 4018

Query: 750  LKWSPPELQLQNGIITGY 767
            L W+PP        ITGY
Sbjct: 4019 LSWTPPRSD-GGADITGY 4035



 Score = 39.9 bits (89), Expect = 0.41
 Identities = 30/104 (28%), Positives = 41/104 (39%), Gaps = 8/104 (7%)

Query: 496  RAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPR 555
            RA     +PGPP  P   +V    +TL+W+     G + ILGY VE    +        +
Sbjct: 2613 RAKPPYDVPGPPGIPDISDVDKNRMTLTWTPPTDDGGAKILGYIVEKCDADRKRWTKAHK 2672

Query: 556  NSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
                       V +    V  L  G  YMF V  EN+ G+   S
Sbjct: 2673 ED--------LVTELTLTVYDLTEGTNYMFRVSAENAAGVGESS 2708



 Score = 39.9 bits (89), Expect = 0.41
 Identities = 31/104 (29%), Positives = 44/104 (42%), Gaps = 11/104 (10%)

Query: 503  LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
            +P  P +P   ++    +T+ WS     G S I GY VE+           P +SR W  
Sbjct: 5177 VPDKPDQPDVTDIDKNEMTVKWSSPYSDGGSKITGYIVEM---------KEPYSSR-WSQ 5226

Query: 563  IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVT 606
            + +    T + V  L  G  Y F +  EN  G S PS  S + T
Sbjct: 5227 VTKTTDFT-FKVTRLTEGKDYQFRIIAENKAGQSQPSEPSRTFT 5269



 Score = 39.9 bits (89), Expect = 0.41
 Identities = 60/250 (24%), Positives = 92/250 (36%), Gaps = 26/250 (10%)

Query: 226  GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVS--- 282
            GG  +   +  R   G  M + R  V+ D S  ++N++   E  +   A N+ G  S   
Sbjct: 9477 GGSEITHYIVERRLKGSYMWIDRT-VVHDTSCSVNNLVEDKEYTFRVTAVNAAGNESDPS 9535

Query: 283  -ASGYLTVYDP-----PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF 336
             AS             PSI +   +  V  G    F C  +G P+P + W   G    + 
Sbjct: 9536 RASESFVAESQLPGAAPSILIEIQNAMVAEGQTGMFMCKISGSPKPKVSWMHHGRE--LM 9593

Query: 337  PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP 396
            PG   +      VF    ++  + TD      TI+  A N  GS     +L +     RP
Sbjct: 9594 PGRKHNITEDNGVF---KIVVFSVTDYETGMYTII--AKNKHGSVRSSAELLI----QRP 9644

Query: 397  PPI-ITNGPSNQTLPIKSMAVFPCT-AICTPEPIIAW-YFEGEALIQNHRRNVTNDGTLV 453
            P + I     + ++        P T    TP+P   W   +GE L    R +    G   
Sbjct: 9645 PQLSIDRHLQDLSVRAGQEIHIPVTLTYGTPKPTFTWRRHDGEELDTRGRYSTKEQGR-- 9702

Query: 454  LKDLDKSDSG 463
            + D +  D G
Sbjct: 9703 VHDFELPDLG 9712



 Score = 39.1 bits (87), Expect = 0.72
 Identities = 41/137 (29%), Positives = 62/137 (45%), Gaps = 12/137 (8%)

Query: 694  ITSLRKYTKYEFFLIPFYKKFEGKPSNSR---VAQTLDDVPDGPPINIEMFILNTTTVHL 750
            IT L +  +YEF +I   K   G+PS+     VA+   +VP  PP +++   L   +V L
Sbjct: 4843 ITDLVEKNEYEFRVIAENKVGPGEPSSPSERIVAKAPYEVP-SPPKSLKATDLTPISVTL 4901

Query: 751  KWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT--SLIMTNLTSGVSYSV 808
             WS P   L NG   G  +V   +++    S    N + H  T  SL + NL     Y  
Sbjct: 4902 NWSAP---LSNG---GSPIVGYTIEMKDKFSTRWTNVSEHMVTTLSLNVPNLKEKNDYQF 4955

Query: 809  QIAAETIIGLGPFSQKV 825
            ++ A    G G  S+ +
Sbjct: 4956 RVIAHNKAGPGQPSEPI 4972



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 42/187 (22%), Positives = 78/187 (41%), Gaps = 20/187 (10%)

Query: 97   RNATLHVAVLREEFRLEPESKQSAQGD-TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155
            +  T  + V   EF     +  +A+ D T+VLEC     +      W K+   +L     
Sbjct: 1071 KTQTADLKVQAAEFVKPLNNTSAAEYDETIVLEC--ELSNELVPCQWYKDD--VLITVGP 1126

Query: 156  RMHLVDGGN---LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVV 212
            ++ ++D G    LV+ D R  D G ++C+     G +ES+ ATL +     +    E   
Sbjct: 1127 KVEVIDDGKKRKLVLHDVRPEDTGNFRCV----VGDKESS-ATLDVKASEIMKPLAEVTA 1181

Query: 213  AQTGSSVTFQCRVGGDPLPDVLWRRSA---GGGNMPLGRVKVLDDGSLR---LDNVILAD 266
             +   +   +C V   P  +  W +         +   + +V+ DG  R   + +V+  D
Sbjct: 1182 PEFAETAVLECEV-SHPKAEATWLKDGQPITPEELTSKKYEVVSDGRKRRLIIHDVVKDD 1240

Query: 267  EGEYSCE 273
              E++C+
Sbjct: 1241 NAEFTCK 1247



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 3/55 (5%)

Query: 503  LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEV---FSRETLSGNNTP 554
            +PG P+ P+  ++T+TSV L WS  +  G + I  Y VE    FS        TP
Sbjct: 2823 VPGAPSTPVPSDITETSVHLEWSPPSNNGGAEITEYIVEQKDRFSSRWTKAGETP 2877



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 6/127 (4%)

Query: 693  EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGP--PINIEMFILNTTTVHL 750
            ++  L +  +YEF +I   K   G+PSN     T     D P  P ++    +  T+  L
Sbjct: 3180 KVNDLTEKNQYEFRVIAENKVGPGEPSNPSARFTAKAPFDEPEAPYSLAASDITPTSATL 3239

Query: 751  KWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQI 810
             W PP+    + I+ GY +     D  +++    +N  + Q TS  +TNL     Y  ++
Sbjct: 3240 SWLPPDSDGGSPIL-GYTLETK--DRFSSR-WTKVNKGLLQETSFKVTNLEENNEYVYRV 3295

Query: 811  AAETIIG 817
             AE   G
Sbjct: 3296 IAENKAG 3302



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 36/139 (25%), Positives = 62/139 (44%), Gaps = 9/139 (6%)

Query: 694  ITSLRKYTKYEFFLIPFYKKFEG---KPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHL 750
            +T L + ++Y+F +I       G   +PS+ + A+   D P  P    E+   + T + L
Sbjct: 2380 VTGLTEGSEYQFRVIAENPAGPGPASEPSDLQKAKLPFDAPSAPG-KPEVTSADKTQMEL 2438

Query: 751  KWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQI 810
             W+ P+       ITGY +          K   ++ TT  + T+ I + L     Y  ++
Sbjct: 2439 TWAVPDSD-GGSPITGYIIQKK---ENTGKWTQSLKTTTTETTATIKS-LIEKKEYEFRV 2493

Query: 811  AAETIIGLGPFSQKVYFNI 829
            AA  + G GPFS+   + I
Sbjct: 2494 AAVNLAGTGPFSEPSDYQI 2512



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 36/131 (27%), Positives = 56/131 (42%), Gaps = 8/131 (6%)

Query: 692  FEITSLRKYTKYEFFLIPFYKKFEGKPS---NSRVAQTLDDVPDGPPINIEMFILNTTTV 748
            F +T L +   Y+F +    K  EG PS   ++  A+   DVP  P   +   I  T+ V
Sbjct: 2782 FTVTGLTEDAIYDFRVSAVNKAGEGPPSLPSDTLKAKLPFDVPGAPSTPVPSDITETS-V 2840

Query: 749  HLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSV 808
            HL+WSPP     NG       +V   D  +++   A   T     ++ + +L  G  Y  
Sbjct: 2841 HLEWSPPS---NNGGAEITEYIVEQKDRFSSRWTKA-GETPGDTVTITLKDLKEGNEYQF 2896

Query: 809  QIAAETIIGLG 819
            ++ A    G G
Sbjct: 2897 RVIAVNPAGPG 2907



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 32/102 (31%), Positives = 46/102 (45%), Gaps = 11/102 (10%)

Query: 502  SLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV 561
            ++P  P  P   NV  TS+T++W+++   G S I GY +E    +  +G         WV
Sbjct: 6269 TVPSAPGAPDVSNVKATSMTVTWTKSISDGGSPITGYVLE--KCDVSTGR--------WV 6318

Query: 562  VIAR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602
             + R  + +T  VV  L     Y F V   N  G S PS  S
Sbjct: 6319 PVNRVPLRETSLVVDQLREKSEYCFRVVAHNVAGESKPSEPS 6360



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 30/115 (26%), Positives = 49/115 (42%), Gaps = 8/115 (6%)

Query: 209  EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---SLRLDNVILA 265
            E ++A+ G S   +    G P P V W    G    P   +++       ++ + NV  A
Sbjct: 8179 EPIMAKVGESFRIEVPYTGIPTPAVTWSFD-GRPLKPSAHIRIDTSNRASTITVKNVEKA 8237

Query: 266  DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
            + G Y+   +N+ GA S    + V+D P     P    +E  NV+  T T +  P
Sbjct: 8238 NGGRYTINLKNTAGAESLDVEVRVFDRPGPPRGP----LEMSNVSESTVTLSWSP 8288



 Score = 37.1 bits (82), Expect = 2.9
 Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 4/88 (4%)

Query: 733  GPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQA 792
            GPP       ++ T++HL WSPP+       +TGY  ++   D   NK    +N      
Sbjct: 2724 GPPPPPTPTHVDRTSIHLTWSPPD-DDGGSEVTGY--ILEKRDKARNK-WTKVNKEPIPE 2779

Query: 793  TSLIMTNLTSGVSYSVQIAAETIIGLGP 820
             S  +T LT    Y  +++A    G GP
Sbjct: 2780 ISFTVTGLTEDAIYDFRVSAVNKAGEGP 2807



 Score = 36.7 bits (81), Expect = 3.9
 Identities = 30/100 (30%), Positives = 43/100 (43%), Gaps = 10/100 (10%)

Query: 503  LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
            +P  P+ P    ++ TS+ L W+     G S I GY +E   ++  SG  TP       V
Sbjct: 3704 VPQAPSAPEVRRLSPTSIQLDWTPPFADGGSDITGYIIE---KKEKSGRWTP-------V 3753

Query: 563  IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602
             +  V  T + VK L       F +   N  G S PS V+
Sbjct: 3754 SSDSVDGTTFTVKGLPDDEDVEFRISAVNKAGQSKPSQVT 3793



 Score = 36.3 bits (80), Expect = 5.1
 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 4/83 (4%)

Query: 404   PSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDK 459
             P   T+ I+  A  F C      EP+I W+   + LI + +  +  D    TL+++D + 
Sbjct: 10652 PLENTMAIEGNAGRFECEVSALSEPLITWFRGKKELIISIKYKMLYDDHKYTLIVQDSEF 10711

Query: 460   SDSGTYTCVASSRHGKYVWSGAL 482
              D   YTC A + +G    S +L
Sbjct: 10712 DDIDEYTCKAVNSYGHATSSASL 10734



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 35/133 (26%), Positives = 59/133 (44%), Gaps = 8/133 (6%)

Query: 688  DVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSR---VAQTLDDVPDGPPINIEMFILN 744
            D     +  L++  +Y+F +I       G PS++    VA+   DVPD P        L+
Sbjct: 2879 DTVTITLKDLKEGNEYQFRVIAVNPAGPGSPSDACKPFVAKPPYDVPDAPGKPAPSD-LS 2937

Query: 745  TTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGV 804
             T+V L W+PP        ITGY V +   D  + +   A    + + T++++ +L    
Sbjct: 2938 PTSVTLTWTPPPSD-GGSPITGYTVEMK--DKFSTRWTKATRELISE-TTVVLPDLKEKE 2993

Query: 805  SYSVQIAAETIIG 817
             Y  ++ AE   G
Sbjct: 2994 EYQFRVIAENKAG 3006



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 30/124 (24%), Positives = 57/124 (45%), Gaps = 8/124 (6%)

Query: 693  EITSLRKYTKYEFFLIPFYKKFEGKPSNSR---VAQTLDDVPDGPPINIEMFILNTTTVH 749
            ++T L + T YEF +I   +  +G+PS      +A++  DVP  P    +   +  T++ 
Sbjct: 3860 KVTDLTEKTDYEFRVIAENRIGQGQPSEPSAKFIAKSPFDVPTAPGAP-KASDITPTSLT 3918

Query: 750  LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQ 809
            L W+PP     +G     N ++ W D  + +  + +   +    +  +T L     Y+ +
Sbjct: 3919 LTWTPP---TDDGGSPITNFIIEWKDKFSTRFTI-LKKDLFVELTFKVTGLKDKTEYTFR 3974

Query: 810  IAAE 813
            I AE
Sbjct: 3975 IIAE 3978



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 22/74 (29%), Positives = 29/74 (39%), Gaps = 1/74 (1%)

Query: 20    DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI-LPAGGLFFLRATHGRVHS 78
             D+ +     A L+C+  G P P IRW+K    +    H SI                   
Sbjct: 10897 DIFIVEGSAARLDCKVTGVPEPNIRWFKDHKEIFDGQHYSIEFGEDDETCSLIIQEAFLQ 10956

Query: 79    DAGVYWCEATNSYG 92
             DAG Y C A+N  G
Sbjct: 10957 DAGTYTCLASNLLG 10970


>UniRef50_Q9BMN8 Cluster: Tyrosine-protein phosphatase Lar-like
           precursor; n=6; Caenorhabditis|Rep: Tyrosine-protein
           phosphatase Lar-like precursor - Caenorhabditis elegans
          Length = 2200

 Score =  102 bits (244), Expect = 7e-20
 Identities = 86/309 (27%), Positives = 129/309 (41%), Gaps = 20/309 (6%)

Query: 14  IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP-AGGLFFLRAT 72
           ++ +P   TV      +  CRA G+P P++ W   G  +      SI   A GL  LR  
Sbjct: 50  LVVRPDSSTVVDESKISFFCRADGNPLPSVIWRVNGKSITDHNRISIKSLATGLSTLRFE 109

Query: 73  HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE------EFRLEPESKQSAQGDTVV 126
              +  +A V  C A N         A+L V    +      +  L P  K   QG T  
Sbjct: 110 RVSLDDNATVVSCSADNGVANPVVAEASLTVVPRDKVPIGFPQIELHPSLKSVEQGKTAY 169

Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIAR 183
           + C   RG P   V W ++   L    D R  +   GN   L+IQ AR+ D G+Y+CIAR
Sbjct: 170 VSCRV-RGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGALMIQHAREEDQGKYECIAR 228

Query: 184 NAAGTRESAIATLKIHIK---PYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
           N  G   S  A L + ++   PY     E   V   G ++   C   G P+P V W+++ 
Sbjct: 229 NTLGVAHSKAANLYVKVRRVPPYFSYKLERQYVVGVGGNINLTCVAVGYPMPRVFWKKT- 287

Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PPSINL 297
               M L        G   L    +     ++C A +++G + A+  +   +  PP +N+
Sbjct: 288 --DLMVLDDPSTAPIGKNVLTLTHVESTENFTCVAVSALGNIEATTTVIAKELPPPPVNI 345

Query: 298 SPNSVNVES 306
             +SV  ES
Sbjct: 346 VVSSVTSES 354



 Score = 64.9 bits (151), Expect = 1e-08
 Identities = 77/286 (26%), Positives = 119/286 (41%), Gaps = 35/286 (12%)

Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT---DAGRYQCIARNAAGTRE 190
           G+P P+V W+ NG+++       +  +  G   ++  R +   +A    C A N      
Sbjct: 73  GNPLPSVIWRVNGKSITDHNRISIKSLATGLSTLRFERVSLDDNATVVSCSADNGVANPV 132

Query: 191 SAIATL------KIHIK-PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
            A A+L      K+ I  P +   P     + G +    CRV GDP   VLW R     +
Sbjct: 133 VAEASLTVVPRDKVPIGFPQIELHPSLKSVEQGKTAYVSCRVRGDPRAKVLWLRDLIPLD 192

Query: 244 MPL-GRVKVL---DDGSLRLDNVILADEGEYSCEAENSVGAV---SASGYLTVYDPP--- 293
           +   GR  V    + G+L + +    D+G+Y C A N++G     +A+ Y+ V   P   
Sbjct: 193 IRADGRYSVSTIGNPGALMIQHAREEDQGKYECIARNTLGVAHSKAANLYVKVRRVPPYF 252

Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
           S  L    V    GN+   TC A G P P +FW       +  P        +TA   G 
Sbjct: 253 SYKLERQYVVGVGGNI-NLTCVAVGYPMPRVFWKKTDLMVLDDP--------STAPI-GK 302

Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPI 399
            VLT+      +S     C AV+  G+  +    TV + +  PPP+
Sbjct: 303 NVLTLTHV---ESTENFTCVAVSALGN--IEATTTVIAKELPPPPV 343



 Score = 61.7 bits (143), Expect = 1e-07
 Identities = 64/276 (23%), Positives = 110/276 (39%), Gaps = 15/276 (5%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGLFFL 69
           P I   P   +V + + A ++CR  G P   + W +  +   + +D   S+   G    L
Sbjct: 151 PQIELHPSLKSVEQGKTAYVSCRVRGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGAL 210

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE----EFRLEPESKQSAQGDTV 125
              H R   D G Y C A N+ G A S+ A L+V V R      ++LE +      G  +
Sbjct: 211 MIQHAR-EEDQGKYECIARNTLGVAHSKAANLYVKVRRVPPYFSYKLERQYVVGV-GGNI 268

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
            L C+   G P P V+WKK    +L D  +    +    L +     T+   + C+A +A
Sbjct: 269 NLTCVAV-GYPMPRVFWKKTDLMVLDDPSTAP--IGKNVLTLTHVESTE--NFTCVAVSA 323

Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD--VLWRRSAGGGN 243
            G  E+    +   + P  +      V      +T++     + +    V +R     G 
Sbjct: 324 LGNIEATTTVIAKELPPPPVNIVVSSVTSESVVITWKPPKYNEAINKYVVNYRLKYSEGR 383

Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279
              G+     + SL +D ++     E++  +   VG
Sbjct: 384 SSRGKTMETLENSLVIDGLVAFQTYEFTVRSAGPVG 419



 Score = 52.8 bits (121), Expect = 5e-05
 Identities = 47/192 (24%), Positives = 76/192 (39%), Gaps = 13/192 (6%)

Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
           DP  + + P+S  V   +   F C A G P P++ W V G           ++    ++ 
Sbjct: 46  DPARLVVRPDSSTVVDESKISFFCRADGNPLPSVIWRVNGKSI-----TDHNRISIKSLA 100

Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV-RGKLTVTSDDDRPP--PIITNGPSNQ 407
            G++ L       +D+   + CSA N   +  V    LTV   D  P   P I   PS +
Sbjct: 101 TGLSTLRFERVSLDDNATVVSCSADNGVANPVVAEASLTVVPRDKVPIGFPQIELHPSLK 160

Query: 408 TLPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRR----NVTNDGTLVLKDLDKSDS 462
           ++     A   C     P   + W  +   L I+   R     + N G L+++   + D 
Sbjct: 161 SVEQGKTAYVSCRVRGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGALMIQHAREEDQ 220

Query: 463 GTYTCVASSRHG 474
           G Y C+A +  G
Sbjct: 221 GKYECIARNTLG 232



 Score = 51.6 bits (118), Expect = 1e-04
 Identities = 80/352 (22%), Positives = 138/352 (39%), Gaps = 39/352 (11%)

Query: 485 DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFS 544
           DSP++  +     A    +PG P       +    + L+W +   + SS ++GY V   +
Sbjct: 521 DSPLSTLV---TVATRQGIPGQPPMLTVKALDSRRMQLTWDK--PLYSSPVVGYTVRYNT 575

Query: 545 RETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPG-----ITYMFIVRTENSHGLSGPS 599
            +              VV      + +Y   +          T   I +T  S  LS P+
Sbjct: 576 SDGEKELTLTSPHEKHVVTGLHPDKYYYFRVAAYSDRGQGEFTEPMISKTIASIPLSSPT 635

Query: 600 PVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFY 659
            VS + T        W+G       +  N +LT + +        DSKT  L  E +   
Sbjct: 636 IVSAAATSSKSVEIRWKGP----EQKKLNGVLTAYRINYFRLE--DSKTANL--ESVE-- 685

Query: 660 YLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPS 719
                  Y   +D+ +   +  +++  +D + + ++ L  Y+ YE  +        G  S
Sbjct: 686 -------YDEDMDDSSSFLDRMSVVVPSDATSYVLSDLLPYSSYEITVAASTMDGYGPES 738

Query: 720 NSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNV----VVNW-- 773
           + RV +TL+DVP  P  N    + + T+V L W  P     NG + GY V    +VN   
Sbjct: 739 SIRVVKTLEDVPSAPR-NFNAELTSATSVKLTWDAP--AAANGALLGYYVYLDRMVNGEP 795

Query: 774 -LDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQK 824
            ++  + K +V I  +  +   L   +L     YS ++ A    G G FS++
Sbjct: 796 VVEKGSKKRIVMIRDSSKRYFEL--DSLDPNTEYSFRLNAFNRNGDGEFSER 845



 Score = 51.2 bits (117), Expect = 2e-04
 Identities = 32/117 (27%), Positives = 58/117 (49%), Gaps = 6/117 (5%)

Query: 715  EGKPSNS-RVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNW 773
            EG+  N+     T    PDG PI+++  ++    V + W PP  + +NG IT Y  +++ 
Sbjct: 940  EGRSQNATETIATPVGSPDGEPIDVQYEVMKGKIV-VSWRPPSEEKRNGNITSYKAILSA 998

Query: 774  LDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNID 830
            +D  A++    +       +S    N+    +Y  ++AA T+ G+GP+S  +  N D
Sbjct: 999  MDATADRYEQPV--PAPSTSSTFEVNVRR--AYLFKVAAATMKGIGPYSPVLTINPD 1051



 Score = 37.1 bits (82), Expect = 2.9
 Identities = 34/124 (27%), Positives = 52/124 (41%), Gaps = 4/124 (3%)

Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTV--H 749
           FE+ SL   T+Y F L  F +  +G+ S  +   T    P+ P I       +   V   
Sbjct: 816 FELDSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQGIPPEAPEIVSVSLDRDEPPVVAR 875

Query: 750 LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQ 809
           ++W  P+++     I  YN+ +     P   S V   T      S  ++ L  GV Y V 
Sbjct: 876 IEWKMPKMKPNETPIEKYNLWLRAQGYP--DSYVKAKTVDGTDLSTTISGLWMGVVYDVL 933

Query: 810 IAAE 813
           +AAE
Sbjct: 934 LAAE 937


>UniRef50_A7RK32 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 1103

 Score =  100 bits (240), Expect = 2e-19
 Identities = 76/300 (25%), Positives = 123/300 (41%), Gaps = 25/300 (8%)

Query: 109 EFRLEPESKQSAQGDTVVLEC---LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNL 165
           +  + P S+++ +GD V L C   +  R S    + W+   + +     +     D  ++
Sbjct: 537 QISVHPPSQKAMRGDNVTLRCRVQVVQRNSSSVRLQWRLGYEVISERDITDFVRTDDDDI 596

Query: 166 VIQDARQ-------TDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSS 218
           V  ++         +DAG YQCIA N  G++ S  A L++   P L   P DV    G  
Sbjct: 597 VTYNSDLFLISVDFSDAGLYQCIASNKYGSQFSKKARLEVLEFPVLTRKPHDVSVHVGGL 656

Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD----DGSLRLDNVILADEGEYSCEA 274
           +   C   G P+P + WR   G    P    K ++    +    + N    D G Y+C A
Sbjct: 657 IKLPCAATGYPVPVISWRMGDGKSKFPAAEEKRIEHLPSEHLFIIRNARGVDTGAYTCTA 716

Query: 275 ENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334
            N  G+++A+ Y+TV + P    S  S  V +G  A   C A+G P P   W  +  +  
Sbjct: 717 TNGAGSINATAYVTVLEVPRFMQSMVSKRVRTGESAVLECKASGSPMPRFTWYKDDKKVT 776

Query: 335 IFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394
           +          A  V  G  ++ +  T   D   T  C   N  G++    +LTV    +
Sbjct: 777 L---------SARVVAHGQLLVFV--TVLRDDEGTYTCQVSNSLGTARQNTRLTVVEGSE 825



 Score = 88.6 bits (210), Expect = 9e-16
 Identities = 83/300 (27%), Positives = 122/300 (40%), Gaps = 23/300 (7%)

Query: 7   TSGEAPYIIEQPLDVTVARHQPATLNCRAG----GSPSPAIRWYKGGVLV----VSDTHR 58
           TS   P I   P      R    TL CR       S S  ++W  G  ++    ++D  R
Sbjct: 531 TSNPIPQISVHPPSQKAMRGDNVTLRCRVQVVQRNSSSVRLQWRLGYEVISERDITDFVR 590

Query: 59  S----ILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP 114
           +    I+      FL +      SDAG+Y C A+N YG+  S+ A L V       R +P
Sbjct: 591 TDDDDIVTYNSDLFLISVD---FSDAGLYQCIASNKYGSQFSKKARLEVLEFPVLTR-KP 646

Query: 115 ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDG--DSRM-HLVDGGNLVIQDAR 171
                  G  + L C    G P P + W+       F    + R+ HL      +I++AR
Sbjct: 647 HDVSVHVGGLIKLPC-AATGYPVPVISWRMGDGKSKFPAAEEKRIEHLPSEHLFIIRNAR 705

Query: 172 QTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231
             D G Y C A N AG+  +A A + +   P  +        +TG S   +C+  G P+P
Sbjct: 706 GVDTGAYTCTATNGAGS-INATAYVTVLEVPRFMQSMVSKRVRTGESAVLECKASGSPMP 764

Query: 232 DVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
              W +      + L    V     L    V+  DEG Y+C+  NS+G    +  LTV +
Sbjct: 765 RFTWYKD--DKKVTLSARVVAHGQLLVFVTVLRDDEGTYTCQVSNSLGTARQNTRLTVVE 822



 Score = 68.9 bits (161), Expect = 8e-10
 Identities = 59/222 (26%), Positives = 90/222 (40%), Gaps = 12/222 (5%)

Query: 254 DGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSVNVESGNVARF 312
           +  L L +V  +D G Y C A N  G+  S    L V + P +   P+ V+V  G + + 
Sbjct: 600 NSDLFLISVDFSDAGLYQCIASNKYGSQFSKKARLEVLEFPVLTRKPHDVSVHVGGLIKL 659

Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
            C ATG P P + W + G+    FP     +           +  I +    D+     C
Sbjct: 660 PCAATGYPVPVISWRM-GDGKSKFPAAEEKRIEH---LPSEHLFIIRNARGVDT-GAYTC 714

Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
           +A N AGS      +TV        P       ++ +     AV  C A  +P P   WY
Sbjct: 715 TATNGAGSINATAYVTVLE-----VPRFMQSMVSKRVRTGESAVLECKASGSPMPRFTWY 769

Query: 433 FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
            + + +  +  R V +   LV   + + D GTYTC  S+  G
Sbjct: 770 KDDKKVTLS-ARVVAHGQLLVFVTVLRDDEGTYTCQVSNSLG 810



 Score = 52.4 bits (120), Expect = 7e-05
 Identities = 35/99 (35%), Positives = 47/99 (47%), Gaps = 6/99 (6%)

Query: 5   YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
           YVT  E P  ++  +   V   + A L C+A GSP P   WYK    V   T  + + A 
Sbjct: 728 YVTVLEVPRFMQSMVSKRVRTGESAVLECKASGSPMPRFTWYKDDKKV---TLSARVVAH 784

Query: 65  GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103
           G   +  T   +  D G Y C+ +NS GTAR +N  L V
Sbjct: 785 GQLLVFVT--VLRDDEGTYTCQVSNSLGTAR-QNTRLTV 820


>UniRef50_Q8IZJ1 Cluster: Netrin receptor UNC5B precursor; n=38;
           Euteleostomi|Rep: Netrin receptor UNC5B precursor - Homo
           sapiens (Human)
          Length = 945

 Score =  100 bits (240), Expect = 2e-19
 Identities = 63/200 (31%), Positives = 98/200 (49%), Gaps = 13/200 (6%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTH---RSILPAGGLFF 68
           PY +++P D  + +++P  L CRA   P+  I +   G  V  + H     +  A GL  
Sbjct: 48  PYFLQEPQDAYIVKNKPVELRCRA--FPATQIYFKCNGEWVSQNDHVTQEGLDEATGLRV 105

Query: 69  ----LRATHGRVHSDAGV--YWCE--ATNSYGTARSRNATLHVAVLREEFRLEPESKQSA 120
               +  +  +V    G+  YWC+  A +S GT +SR A + +A LR+ F  EP  K+  
Sbjct: 106 REVQIEVSRQQVEELFGLEDYWCQCVAWSSAGTTKSRRAYVRIAYLRKNFDQEPLGKEVP 165

Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
               V+L+C PP G P   V W KN   +    D+   L    NL+I+ AR +D   Y C
Sbjct: 166 LDHEVLLQCRPPEGVPVAEVEWLKNEDVIDPTQDTNFLLTIDHNLIIRQARLSDTANYTC 225

Query: 181 IARNAAGTRESAIATLKIHI 200
           +A+N    R S  AT+ +++
Sbjct: 226 VAKNIVAKRRSTTATVIVYV 245


>UniRef50_Q6UWL6 Cluster: Kin of IRRE-like protein 2 precursor;
           n=19; Theria|Rep: Kin of IRRE-like protein 2 precursor -
           Homo sapiens (Human)
          Length = 708

 Score =  100 bits (240), Expect = 2e-19
 Identities = 107/396 (27%), Positives = 159/396 (40%), Gaps = 37/396 (9%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGS--PSPAIRWYKGGVLVVSDT-HRSILPAGGL 66
           EAP ++  P  V++    PA L CR+ G   P+P + W++ GVL+   T H+++L  G  
Sbjct: 124 EAPQVLGGP-SVSLVAGVPANLTCRSRGDARPTPELLWFRDGVLLDGATFHQTLLKEGTP 182

Query: 67  FFLRATHGRV---HSDAGVYWCEA-TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122
             + +T       H D   + C A + +  T R    TL +     E  L        +G
Sbjct: 183 GSVESTLTLTPFSHDDGATFVCRARSQALPTGRDTAITLSLQY-PPEVTLSASPHTVQEG 241

Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
           + V+  C      P     W K G  +L     R+ +V   + + +           C  
Sbjct: 242 EKVIFLCQATAQPPVTGYRWAKGGSPVLGARGPRLEVVADASFLTEPV--------SCEV 293

Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
            NA G+   + A L +   P L   PE V    G   +F C   G+PLP V W R   GG
Sbjct: 294 SNAVGSANRSTA-LDVLFGPILQAKPEPVSVDVGEDASFSCAWRGNPLPRVTWTRR--GG 350

Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV---SASGYLTVYDPPSINLSP 299
              LG        +LRL +V   D G+Y C AE  +  +   +A   LTV  PP +  + 
Sbjct: 351 AQVLG-----SGATLRLPSVGPEDAGDYVCRAEAGLSGLRGGAAEARLTVNAPPVVT-AL 404

Query: 300 NSVNVESGNVARFTCTATGRPEP-TMFWS-VEGNRTIIFPG-MSRDKYHATAVFDG---- 352
           +S        AR  C     P P  + WS  EG       G    + + A     G    
Sbjct: 405 HSAPAFLRGPARLQCLVFASPAPDAVVWSWDEGFLEAGSQGRFLVETFPAPESRGGLGPG 464

Query: 353 -VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387
            ++VL I+ T ++D   +  CSA N  G    +  L
Sbjct: 465 LISVLHISGTQESDFSRSFNCSARNRLGEGGAQASL 500



 Score = 89.0 bits (211), Expect = 7e-16
 Identities = 121/455 (26%), Positives = 187/455 (41%), Gaps = 67/455 (14%)

Query: 8   SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
           +G +P+ ++QP D+ V   + A L C A G+    ++W K G+ +        LP    +
Sbjct: 20  AGPSPHFLQQPEDLVVLLGEEARLPC-ALGAYWGLVQWTKSGLALGGQRD---LPGWSRY 75

Query: 68  FL--RATHGR--VH------SDAGVYWCEATNSYGTARSRNATLHVAVLREEFR-LEPES 116
           ++   A +G+  +H       D   Y C+AT +    RSR A LHV V  E  + L   S
Sbjct: 76  WISGNAANGQHDLHIRPVELEDEASYECQATQA--GLRSRPAQLHVLVPPEAPQVLGGPS 133

Query: 117 KQSAQGDTVVLECLPPRGS--PEPNVYWKKNGQTLLFDGDS--RMHLVDG------GNLV 166
                G    L C   RG   P P + W ++G  +L DG +  +  L +G        L 
Sbjct: 134 VSLVAGVPANLTCRS-RGDARPTPELLWFRDG--VLLDGATFHQTLLKEGTPGSVESTLT 190

Query: 167 IQDARQTDAGRYQCIARNAA--GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR 224
           +      D   + C AR+ A    R++AI TL +   P +         Q G  V F C+
Sbjct: 191 LTPFSHDDGATFVCRARSQALPTGRDTAI-TLSLQYPPEVTLSASPHTVQEGEKVIFLCQ 249

Query: 225 VGGDPLPDVLWRRSAGGGNMPLG----RVKVLDDGSLRLDNVILADEGEYSCEAENSVGA 280
               P   V   R A GG+  LG    R++V+ D S   + V        SCE  N+VG+
Sbjct: 250 ATAQP--PVTGYRWAKGGSPVLGARGPRLEVVADASFLTEPV--------SCEVSNAVGS 299

Query: 281 VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340
            + S  L V   P +   P  V+V+ G  A F+C   G P P + W+  G   ++  G +
Sbjct: 300 ANRSTALDVLFGPILQAKPEPVSVDVGEDASFSCAWRGNPLPRVTWTRRGGAQVLGSGAT 359

Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII 400
                       + + ++   D  D     VC A   AG S +RG           PP++
Sbjct: 360 ------------LRLPSVGPEDAGD----YVCRA--EAGLSGLRGGAAEARLTVNAPPVV 401

Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEP-IIAWYFE 434
           T   S     ++  A   C    +P P  + W ++
Sbjct: 402 TALHSAPAF-LRGPARLQCLVFASPAPDAVVWSWD 435


>UniRef50_UPI0000F20186 Cluster: PREDICTED: similar to cell adhesion
           molecule NCAM; n=7; Danio rerio|Rep: PREDICTED: similar
           to cell adhesion molecule NCAM - Danio rerio
          Length = 1157

 Score =  100 bits (239), Expect = 3e-19
 Identities = 75/288 (26%), Positives = 125/288 (43%), Gaps = 10/288 (3%)

Query: 43  IRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLH 102
           I W K G  V +D H           L   + ++ SD G Y CE  +S G  ++ N+ ++
Sbjct: 528 INWLKDGEDVDTDRHVVEKNDESSSTLNLKNVQL-SDTGRYTCEFEDSNGNKKTTNSQIY 586

Query: 103 VAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG 162
           V     +F       +     T ++ C+   G PE  ++W +N + +  DG S + ++  
Sbjct: 587 V-YKTPDFGQTRTFHEFLVNQTAIIPCMVT-GKPEVEIHWFRNDRMIHDDGRSHLKILPD 644

Query: 163 GNLVIQDARQTDAGRYQCIARNAAG--TRESAIATLKIHIKPYLITGPE--DVVAQTGSS 218
             L+I   +  D G Y C  +      TR   I+ + ++  P ++   E   V A   +S
Sbjct: 645 RTLMIVGIQHEDRGTYICEGKIKGRPITRNLPISVV-VNEPPTVLIHEEKKSVFAGPNTS 703

Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSV 278
           ++  C V G P+P + W   +   +         D   L +  V  +D GEY C A N +
Sbjct: 704 LSIACLVKGAPVPTITWTTPSSFNDYRYSYNT--DKSELTISAVTRSDYGEYICTASNKI 761

Query: 279 GAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326
           G  SA   L V + P++  + N +++  G  A   C ATG P P + W
Sbjct: 762 GESSAIFVLDVSELPTVVFTENKLSIIPGESASVFCNATGHPAPAVQW 809



 Score = 86.2 bits (204), Expect = 5e-15
 Identities = 77/283 (27%), Positives = 114/283 (40%), Gaps = 24/283 (8%)

Query: 26  HQPATLNCRAGGSPSPAIRWYKGGVLVVSD--THRSILPAGGLFFLRATHGRVHSDAGVY 83
           +Q A + C   G P   I W++   ++  D  +H  ILP   L  +    G  H D G Y
Sbjct: 605 NQTAIIPCMVTGKPEVEIHWFRNDRMIHDDGRSHLKILPDRTLMIV----GIQHEDRGTY 660

Query: 84  WCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA---QGDTVVLECLPPRGSPEPNV 140
            CE     G   +RN  + V V      L  E K+S       ++ + CL  +G+P P +
Sbjct: 661 ICEGKIK-GRPITRNLPISVVVNEPPTVLIHEEKKSVFAGPNTSLSIACLV-KGAPVPTI 718

Query: 141 YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
            W        F+     +  D   L I    ++D G Y C A N  G   SAI  L +  
Sbjct: 719 TWTTPSS---FNDYRYSYNTDKSELTISAVTRSDYGEYICTASNKIG-ESSAIFVLDVSE 774

Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLD 260
            P ++     +    G S +  C   G P P V W R          + K+  +  L L+
Sbjct: 775 LPTVVFTENKLSIIPGESASVFCNATGHPAPAVQWVRKDT-------QQKMSGEPELILE 827

Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVY--DPPSINLSPNS 301
           N++ +D G YSC A N VG  +    L  +   P   ++S  S
Sbjct: 828 NIMPSDGGFYSCIATNIVGTTTGDFQLITWPETPSQFSMSAGS 870



 Score = 78.2 bits (184), Expect = 1e-12
 Identities = 82/363 (22%), Positives = 164/363 (45%), Gaps = 45/363 (12%)

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-----GGNLVIQDARQTDAG 176
           G++++L C   +   E ++ W K+G+    D D+  H+V+        L +++ + +D G
Sbjct: 513 GNSILLLC---KADTEGDINWLKDGE----DVDTDRHVVEKNDESSSTLNLKNVQLSDTG 565

Query: 177 RYQCIARNAAGTRESAIATLKIHIKP---YLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233
           RY C   ++ G +++  + + ++  P      T  E +V QT       C V G P  ++
Sbjct: 566 RYTCEFEDSNGNKKTTNSQIYVYKTPDFGQTRTFHEFLVNQTA---IIPCMVTGKPEVEI 622

Query: 234 LW-RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-- 290
            W R      +     +K+L D +L +  +   D G Y CE +     ++ +  ++V   
Sbjct: 623 HWFRNDRMIHDDGRSHLKILPDRTLMIVGIQHEDRGTYICEGKIKGRPITRNLPISVVVN 682

Query: 291 DPPSINLSPNSVNVESG-NVA-RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
           +PP++ +     +V +G N +    C   G P PT+ W+   +        + DK     
Sbjct: 683 EPPTVLIHEEKKSVFAGPNTSLSIACLVKGAPVPTITWTTPSSFNDYRYSYNTDK----- 737

Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408
                + LTI+   ++D     +C+A N  G S     + V    + P  + T    +  
Sbjct: 738 -----SELTISAVTRSDY-GEYICTASNKIGES---SAIFVLDVSELPTVVFTENKLS-I 787

Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468
           +P +S +VF C A   P P + W      + ++ ++ ++ +  L+L+++  SD G Y+C+
Sbjct: 788 IPGESASVF-CNATGHPAPAVQW------VRKDTQQKMSGEPELILENIMPSDGGFYSCI 840

Query: 469 ASS 471
           A++
Sbjct: 841 ATN 843



 Score = 71.7 bits (168), Expect = 1e-10
 Identities = 79/332 (23%), Positives = 131/332 (39%), Gaps = 24/332 (7%)

Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS- 256
           I  K  +I G  DV  Q G+S+   C+   D   D+ W +     +     V+  D+ S 
Sbjct: 497 IDAKLDIILGDPDV--QVGNSILLLCKA--DTEGDINWLKDGEDVDTDRHVVEKNDESSS 552

Query: 257 -LRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
            L L NV L+D G Y+CE E+S G   + +  + VY  P    +           A   C
Sbjct: 553 TLNLKNVQLSDTGRYTCEFEDSNGNKKTTNSQIYVYKTPDFGQTRTFHEFLVNQTAIIPC 612

Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
             TG+PE  + W    +R I   G S  K     +    T++ +    +++ R T +C  
Sbjct: 613 MVTGKPEVEIHW-FRNDRMIHDDGRSHLK-----ILPDRTLMIVGI--QHEDRGTYICEG 664

Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL--PIKSMAVFPCTAICTPEPIIAWY 432
               G    R  L ++   + PP ++ +         P  S+++  C     P P I W 
Sbjct: 665 -KIKGRPITRN-LPISVVVNEPPTVLIHEEKKSVFAGPNTSLSI-ACLVKGAPVPTITWT 721

Query: 433 FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
                    +  N T+   L +  + +SD G Y C AS++ G+   S   ++D    P +
Sbjct: 722 TPSSFNDYRYSYN-TDKSELTISAVTRSDYGEYICTASNKIGES--SAIFVLDVSELPTV 778

Query: 493 HFFRAADVSSLPGPPTKPITHNVTDTSVTLSW 524
             F    +S +PG       +     +  + W
Sbjct: 779 -VFTENKLSIIPGESASVFCNATGHPAPAVQW 809



 Score = 39.1 bits (87), Expect = 0.72
 Identities = 47/186 (25%), Positives = 73/186 (39%), Gaps = 20/186 (10%)

Query: 6   VTSGEAPYII--EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
           V   E P ++  E+   V    +   ++ C   G+P P I W        +D   S    
Sbjct: 679 VVVNEPPTVLIHEEKKSVFAGPNTSLSIACLVKGAPVPTITWTTPSSF--NDYRYSYNTD 736

Query: 64  GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS-AQG 122
                + A      SD G Y C A+N  G + S    L V+ L     +  E+K S   G
Sbjct: 737 KSELTISAV---TRSDYGEYICTASNKIGES-SAIFVLDVSELPTV--VFTENKLSIIPG 790

Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
           ++  + C    G P P V W +         D++  +     L++++   +D G Y CIA
Sbjct: 791 ESASVFC-NATGHPAPAVQWVRK--------DTQQKMSGEPELILENIMPSDGGFYSCIA 841

Query: 183 RNAAGT 188
            N  GT
Sbjct: 842 TNIVGT 847


>UniRef50_Q4S556 Cluster: Chromosome 6 SCAF14737, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 6
           SCAF14737, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 1089

 Score =  100 bits (239), Expect = 3e-19
 Identities = 96/304 (31%), Positives = 134/304 (44%), Gaps = 35/304 (11%)

Query: 20  DVTVARHQPATLNCRAGGS-PSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
           ++ V     A + C    S P   +R+  K   L  S  +  I+P+G L    AT     
Sbjct: 165 EIEVDEGNTAVIECHLPESQPKAQVRYSVKQEWLETSKGNYLIMPSGNLQIANATQ---- 220

Query: 78  SDAGVYWCEATN----------SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
            D G Y C A N          S    R R +T   A  R  +     S  + +G  +VL
Sbjct: 221 EDEGPYKCAAYNPVTQEVKTSISADRLRIRRSTSEAA--RIIYPPASRSIMATKGQRLVL 278

Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
           EC+   G P P V W K+GQ L +  ++R  L    NL+I    ++D+G Y C A N   
Sbjct: 279 ECVAS-GIPTPQVTWAKDGQDLRYVNNTRFLL---SNLLIDAVGESDSGTYACQADNGIL 334

Query: 188 TRESAIATLKIHI-KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
              SA+    + + +P  +T   ++    G +V F C+  G P P V W  +A   + P 
Sbjct: 335 ASASAMVLYNVQVSEPPQVT--VELQQVYGGTVRFTCQARGKPAPSVTWLHNARPLS-PS 391

Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--------PPSINLS 298
            R + L    LR+ NV L DEG Y C AEN VG+  AS  L +          PPSI LS
Sbjct: 392 PRHR-LTSRMLRVSNVGLQDEGLYQCMAENGVGSSQASARLIIASAVVPPRGKPPSIFLS 450

Query: 299 PNSV 302
           P+ V
Sbjct: 451 PDKV 454



 Score = 98.3 bits (234), Expect = 1e-18
 Identities = 89/333 (26%), Positives = 144/333 (43%), Gaps = 31/333 (9%)

Query: 10  EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGGLFF 68
           E P   E+P  V        +L C A   P+ A I W   G  ++     ++L    L+ 
Sbjct: 64  EVPVFTEEPASVVQKLGGSVSLRCSA--RPALANISWRLNGQELLDGDFGAVLGPNSLYI 121

Query: 69  LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GDTV 125
              ++  +    G Y C A+   G   S  A +  A LR+    EP+  Q  +   G+T 
Sbjct: 122 PSLSNLTL----GRYQCVASTGVGALASVLANVTAAKLRD---FEPDDHQEIEVDEGNTA 174

Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
           V+EC  P   P+  V +    Q  L        ++  GNL I +A Q D G Y+C A N 
Sbjct: 175 VIECHLPESQPKAQVRYSVK-QEWLETSKGNYLIMPSGNLQIANATQEDEGPYKCAAYNP 233

Query: 186 AGTR-ESAIATLKIHIK------PYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
                +++I+  ++ I+        +I  P    ++A  G  +  +C   G P P V W 
Sbjct: 234 VTQEVKTSISADRLRIRRSTSEAARIIYPPASRSIMATKGQRLVLECVASGIPTPQVTWA 293

Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYL---TVYDPP 293
           +  G     +   + L   +L +D V  +D G Y+C+A+N + A +++  L    V +PP
Sbjct: 294 KD-GQDLRYVNNTRFL-LSNLLIDAVGESDSGTYACQADNGILASASAMVLYNVQVSEPP 351

Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326
            + +    V    G   RFTC A G+P P++ W
Sbjct: 352 QVTVELQQV---YGGTVRFTCQARGKPAPSVTW 381



 Score = 77.4 bits (182), Expect = 2e-12
 Identities = 91/393 (23%), Positives = 148/393 (37%), Gaps = 33/393 (8%)

Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
           F  EP S     G +V L C         N+ W+ NGQ LL DGD    ++   +L I  
Sbjct: 68  FTEEPASVVQKLGGSVSLRCSARPALA--NISWRLNGQELL-DGDFGA-VLGPNSLYIPS 123

Query: 170 ARQTDAGRYQCIARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVG-G 227
                 GRYQC+A    G   S +A +    ++ +     +++    G++   +C +   
Sbjct: 124 LSNLTLGRYQCVASTGVGALASVLANVTAAKLRDFEPDDHQEIEVDEGNTAVIECHLPES 183

Query: 228 DPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG-----AVS 282
            P   V +           G   ++  G+L++ N    DEG Y C A N V      ++S
Sbjct: 184 QPKAQVRYSVKQEWLETSKGNYLIMPSGNLQIANATQEDEGPYKCAAYNPVTQEVKTSIS 243

Query: 283 ASGYL---TVYDPPSINLSP--NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337
           A       +  +   I   P   S+    G      C A+G P P + W+ +G       
Sbjct: 244 ADRLRIRRSTSEAARIIYPPASRSIMATKGQRLVLECVASGIPTPQVTWAKDG------- 296

Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397
              +D  +       ++ L I+   ++DS  T  C A N  G       + + +     P
Sbjct: 297 ---QDLRYVNNTRFLLSNLLIDAVGESDS-GTYACQADN--GILASASAMVLYNVQVSEP 350

Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL 457
           P +T               F C A   P P + W      L  + R  +T+   L + ++
Sbjct: 351 PQVT---VELQQVYGGTVRFTCQARGKPAPSVTWLHNARPLSPSPRHRLTS-RMLRVSNV 406

Query: 458 DKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
              D G Y C+A +  G    S  L++ S + P
Sbjct: 407 GLQDEGLYQCMAENGVGSSQASARLIIASAVVP 439



 Score = 40.3 bits (90), Expect = 0.31
 Identities = 57/239 (23%), Positives = 94/239 (39%), Gaps = 30/239 (12%)

Query: 492 IHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGN 551
           + F  A    + P  P KP     T+TS  ++W      G   I  ++VE + +   +G 
Sbjct: 628 VPFHTAPPPPAAPEAPDKPTVSAATETSAYVTWIPRGNRG-FPIQSFRVE-YKKVKKAGE 685

Query: 552 NTPRNSRGWVVIARRVHQTHYVVK--SLIPGITYMFIVRTENSHGLSGPSPVSD--SVTV 607
           +       WV     +  +   V+   L  G +Y F V   N  G S PS  S   +V V
Sbjct: 686 D-------WVTAVENIPPSRLSVEITGLEKGTSYKFRVVAVNVIGSSPPSAPSKAYAVVV 738

Query: 608 GDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIY 667
           G       +G  ++    Y   I    I+     TP+++  I             G +IY
Sbjct: 739 GRTPERPVDGPYIT----YNEAINETSIILKWTYTPVNNTPI------------YGFYIY 782

Query: 668 FRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQT 726
           +RP D+   + + K  +   D     IT+L+  T Y+  +  F +K E +  N  + +T
Sbjct: 783 YRPTDSDN-DSDYKKDVVEGDKYWHSITNLQPETAYDIKMQSFNEKGESEFGNVVILET 840


>UniRef50_UPI0000E4A8AD Cluster: PREDICTED: similar to Ptprd
           protein, partial; n=5; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to Ptprd protein,
           partial - Strongylocentrotus purpuratus
          Length = 1773

 Score =   99 bits (238), Expect = 4e-19
 Identities = 133/537 (24%), Positives = 211/537 (39%), Gaps = 75/537 (13%)

Query: 293 PSINLSPNS-VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
           P I  +P   + VE+   A   C ATG PEP + W  E       P  + D+   T    
Sbjct: 70  PEITSNPRRYMVVENNRPATIYCGATGNPEPEILWFKE-----FVPIEANDRISMTDSGL 124

Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
             +   ++D  + +      C+A N  G+ +   +  V   D +  P  T  P NQ +  
Sbjct: 125 QFSRAQLSDQGRYE------CAAKNSLGTRY-SVEAQVYVKDRQVEPRFTILPENQEVVP 177

Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
                  C A  +P P + W   G  L       +   G  VL+  D  +S  YTCVA+S
Sbjct: 178 GGSVNLTCAAYGSPMPRVRWMKAGMDLDDMDDLPI---GRNVLQLRDIYESANYTCVATS 234

Query: 472 RHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIG 531
             G         +D+             V + P  P  P+    T +S+T+ WS    + 
Sbjct: 235 LLGT--------IDTSAR--------VTVRTRPSVPNSPVVTGYTSSSLTVEWST---LS 275

Query: 532 SSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTEN 591
           S ++  + +E + R    G+ T                T + ++ L+P   Y   +   N
Sbjct: 276 SDTVTSHVLE-YKRSRSGGSFTEMEIPS-------PQDTSFTIEGLLPYTEYAVRLLAVN 327

Query: 592 SHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKL 651
           S G S PS   D VT          G  V +  E              E   I +  I+L
Sbjct: 328 SIGRSNPS---DEVTA-------MTGEDVPSQPEQ------------FEGVAISASQIRL 365

Query: 652 MWEILNFYYLEGLFIYFRPLDNI-TIEYEM-KTILHSNDVSGFEITSLRKYTKYEFFLIP 709
            W + +    E   I +    N+ T + +M KTI  + D   + + +LR  T Y   L  
Sbjct: 366 TWMMRD---TEPQIIRYELYYNVSTNDNDMHKTITPTTD---YVLDNLRPNTLYHIRLAA 419

Query: 710 FYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNV 769
             +  EG  S     +T    P  PP  +   +L++T++ ++WSPP L+ QNG ITGY +
Sbjct: 420 RSETGEGASSPVITVRTQQSAPGAPPQEVSGTVLSSTSIEVRWSPPPLEDQNGDITGYKI 479

Query: 770 VVNWLDVPANKSMVAINTTVH-QATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
           +   + + +  +   +N  V     S I+  L     Y +++ A T IG GP S  +
Sbjct: 480 IYRKMSLVSTNN-PEMNVPVEADVRSYILEALRKYTLYDIRVVACTAIGDGPPSDSL 535



 Score = 93.1 bits (221), Expect = 4e-17
 Identities = 85/284 (29%), Positives = 132/284 (46%), Gaps = 18/284 (6%)

Query: 21  VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
           + V  ++PAT+ C A G+P P I W+K  V + ++   S+  + GL F RA      SD 
Sbjct: 80  MVVENNRPATIYCGATGNPEPEILWFKEFVPIEANDRISMTDS-GLQFSRAQ----LSDQ 134

Query: 81  GVYWCEATNSYGTARSRNATLHVAVLREE--FRLEPESKQSAQGDTVVLECLPPRGSPEP 138
           G Y C A NS GT  S  A ++V   + E  F + PE+++   G +V L C    GSP P
Sbjct: 135 GRYECAAKNSLGTRYSVEAQVYVKDRQVEPRFTILPENQEVVPGGSVNLTC-AAYGSPMP 193

Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
            V W K G  L    D    L  G N V+Q     ++  Y C+A +  GT +++ A + +
Sbjct: 194 RVRWMKAGMDL----DDMDDLPIGRN-VLQLRDIYESANYTCVATSLLGTIDTS-ARVTV 247

Query: 199 HIKPYLITGPEDVVAQTGSSVTFQ-CRVGGDPLPD-VL-WRRSAGGGNMPLGRVKVLDDG 255
             +P +   P  V   T SS+T +   +  D +   VL ++RS  GG+     +    D 
Sbjct: 248 RTRPSVPNSPV-VTGYTSSSLTVEWSTLSSDTVTSHVLEYKRSRSGGSFTEMEIPSPQDT 306

Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
           S  ++ ++   E      A NS+G  + S  +T      +   P
Sbjct: 307 SFTIEGLLPYTEYAVRLLAVNSIGRSNPSDEVTAMTGEDVPSQP 350



 Score = 78.6 bits (185), Expect = 1e-12
 Identities = 46/163 (28%), Positives = 82/163 (50%), Gaps = 6/163 (3%)

Query: 661 LEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN 720
           + G  I +R +  ++       +    DV  + + +LRKYT Y+  ++      +G PS+
Sbjct: 474 ITGYKIIYRKMSLVSTNNPEMNVPVEADVRSYILEALRKYTLYDIRVVACTAIGDGPPSD 533

Query: 721 SRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNV----VVNWLDV 776
           S   +T +D P+GPP  + + + N+TT+ ++W  P+  LQNG I GY +    V    D 
Sbjct: 534 SLSIRTAEDAPEGPPRKVRVRVHNSTTIRVQWQAPDPDLQNGEIRGYRIDYQTVTEEGDP 593

Query: 777 PANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819
             +  ++ IN         ++++L     YS++IAA T+ G G
Sbjct: 594 VGSPQVLFINQP--DLRVAVLSDLLPKTFYSIEIAAFTVRGDG 634



 Score = 62.9 bits (146), Expect = 5e-08
 Identities = 39/142 (27%), Positives = 70/142 (49%), Gaps = 9/142 (6%)

Query: 684 LHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDD-VPDGPPINIEMFI 742
           L  ++   +    LR  T+YEF L    +  EG  + +    T  +  P G P+N+    
Sbjct: 698 LRPSEFQSYTFDDLRLGTRYEFKLTASNE--EGNSNEAIFYYTTHEGTPSGSPMNVTASP 755

Query: 743 LNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTS 802
           L+++++ + W PP  + +NG+I  Y +      +P   +    N T    T +++T+L  
Sbjct: 756 LSSSSISVSWDPPLEEERNGLILKYTIRYYSSAMPTELT----NRTTE--TDIVLTSLVP 809

Query: 803 GVSYSVQIAAETIIGLGPFSQK 824
             +YSV++ A T +G GP+S K
Sbjct: 810 NTAYSVEVRAHTSVGPGPYSTK 831



 Score = 60.1 bits (139), Expect = 4e-07
 Identities = 55/219 (25%), Positives = 91/219 (41%), Gaps = 26/219 (11%)

Query: 202 PYLITGPED-VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSL 257
           P + + P   +V +     T  C   G+P P++LW +      +P+    R+ + D G L
Sbjct: 70  PEITSNPRRYMVVENNRPATIYCGATGNPEPEILWFKEF----VPIEANDRISMTDSG-L 124

Query: 258 RLDNVILADEGEYSCEAENSVGA-VSASGYLTVYD---PPSINLSPNSVNVESGNVARFT 313
           +     L+D+G Y C A+NS+G   S    + V D    P   + P +  V  G     T
Sbjct: 125 QFSRAQLSDQGRYECAAKNSLGTRYSVEAQVYVKDRQVEPRFTILPENQEVVPGGSVNLT 184

Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
           C A G P P + W        +  GM  D      +  G  VL + D    +S N   C 
Sbjct: 185 CAAYGSPMPRVRW--------MKAGMDLDDMDDLPI--GRNVLQLRDI--YESAN-YTCV 231

Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
           A +  G+     ++TV +    P   +  G ++ +L ++
Sbjct: 232 ATSLLGTIDTSARVTVRTRPSVPNSPVVTGYTSSSLTVE 270


>UniRef50_UPI000065CE26 Cluster: Homolog of Homo sapiens
           "Hemicentin; n=1; Takifugu rubripes|Rep: Homolog of Homo
           sapiens "Hemicentin - Takifugu rubripes
          Length = 632

 Score =   99 bits (238), Expect = 4e-19
 Identities = 80/295 (27%), Positives = 116/295 (39%), Gaps = 21/295 (7%)

Query: 13  YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-----DTHRS----ILPA 63
           +II  P ++TV      +++C  GG P P + W+K G L+ +       H +     + +
Sbjct: 95  HIIHGPDNITVTLATEVSMHCTVGGFPVPTVHWFKDGCLLTNCSASFSLHNNGQLLTIMS 154

Query: 64  GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
           G  F   +     H    +  CE       A      + V  +   F   P +    QG+
Sbjct: 155 GTCFSFYSFKKTNHKTKLIICCELVAFVQLA--NKTCVMVPEMDWSFVQHPANMTVKQGE 212

Query: 124 TVVLECLPPRGSPEPNVYWKKNGQ--------TLLFDGDSRMHLVDGGNLVIQDARQTDA 175
            V + C PP   P   V W KN Q         +L  GD     +    L I+  R  D 
Sbjct: 213 NVTVVCRPPCSRPTAQVSWFKNNQLYIPTNHVAVLPSGDLFFQRLRNTTLHIESVRIYDE 272

Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVL 234
           G Y C+A NA G    A A L + + P ++T    V    G  V   CR VG +P+    
Sbjct: 273 GVYVCVASNALGQSNDA-ALLTVAVSPIIVTFLSRVSTLIGDLVVLPCRAVGIEPITYTW 331

Query: 235 WRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
            +        P G     +DG+LR+     +D GEY C AEN  G       LT+
Sbjct: 332 TKGKEEDPISPAGDKHTDEDGALRISTTQQSDAGEYYCTAENRAGRHQRRAILTI 386



 Score = 53.2 bits (122), Expect = 4e-05
 Identities = 55/196 (28%), Positives = 86/196 (43%), Gaps = 20/196 (10%)

Query: 208 PEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGNMPLGRVKVLDDG----------S 256
           P ++  + G +VT  CR     P   V W ++     +P   V VL  G          +
Sbjct: 203 PANMTVKQGENVTVVCRPPCSRPTAQVSWFKN-NQLYIPTNHVAVLPSGDLFFQRLRNTT 261

Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316
           L +++V + DEG Y C A N++G  + +  LTV   P I    + V+   G++    C A
Sbjct: 262 LHIESVRIYDEGVYVCVASNALGQSNDAALLTVAVSPIIVTFLSRVSTLIGDLVVLPCRA 321

Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
            G    T  W+       I P  + DK+      DG   L I+ T ++D+     C+A N
Sbjct: 322 VGIEPITYTWTKGKEEDPISP--AGDKHTDE---DG--ALRISTTQQSDA-GEYYCTAEN 373

Query: 377 YAGSSFVRGKLTVTSD 392
            AG    R  LT+T++
Sbjct: 374 RAGRHQRRAILTITAE 389



 Score = 42.7 bits (96), Expect = 0.059
 Identities = 35/123 (28%), Positives = 53/123 (43%), Gaps = 9/123 (7%)

Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA 430
           VC A N  G S     LTV        PII    S  +  I  + V PC A+   EPI  
Sbjct: 276 VCVASNALGQSNDAALLTVAVS-----PIIVTFLSRVSTLIGDLVVLPCRAVGI-EPITY 329

Query: 431 WYFEG---EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
            + +G   + +     ++   DG L +    +SD+G Y C A +R G++     L + + 
Sbjct: 330 TWTKGKEEDPISPAGDKHTDEDGALRISTTQQSDAGEYYCTAENRAGRHQRRAILTITAE 389

Query: 488 INP 490
            +P
Sbjct: 390 HHP 392


>UniRef50_P34082 Cluster: Fasciclin-2 precursor; n=7; Diptera|Rep:
           Fasciclin-2 precursor - Drosophila melanogaster (Fruit
           fly)
          Length = 873

 Score =   99 bits (238), Expect = 4e-19
 Identities = 100/415 (24%), Positives = 168/415 (40%), Gaps = 36/415 (8%)

Query: 81  GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
           G Y+C A+ +      +  T+   V    +   PE++    G   V+ C   +  P P +
Sbjct: 112 GKYYCTASYANTEILEKGVTIKTYVAIT-WTNAPENQYPTLGQDYVVMC-EVKADPNPTI 169

Query: 141 YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH- 199
            W +NG  +    D   ++V    L+I++ +++D G Y C A     T E    T+++  
Sbjct: 170 DWLRNGDPIRTTNDK--YVVQTNGLLIRNVQESDEGIYTCRAA-VIETGELLERTIRVEV 226

Query: 200 -IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKV-LDDGS 256
            I+P +I+ P ++ A  G      C   G P+P++ W R A   N+    R +V    G 
Sbjct: 227 FIQPEIISLPTNLEAVEGKPFAANCTARGKPVPEISWIRDATQLNVATADRFQVNPQTGL 286

Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316
           + + +V   D G Y+C A+N  G V     L V   P I    N     +  +A  TC A
Sbjct: 287 VTISSVSQDDYGTYTCLAKNRAGVVDQKTKLNVLVRPQIYELYNVTGARTKEIA-ITCRA 345

Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRD--KYHATAVFD-----GVTVLTINDTDKNDSRNT 369
            GRP P + +   G +     G   D  +      FD         L I++ +++D    
Sbjct: 346 KGRPAPAITFRRWGTQEEYTNGQQDDDPRIILEPNFDEERGESTGTLRISNAERSDD-GL 404

Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDD-----RPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
             C A N    ++  G +TV    D       PP+ +       L         C A+  
Sbjct: 405 YQCIARNKGADAYKTGHITVEFAPDFSHMKELPPVFSWEQRKANL--------SCLAMGI 456

Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGT-----LVLKDLDKSDSGTYTCVASSRHG 474
           P   I W++ G  +   +  N+   GT     L++  + +     Y C+A++ HG
Sbjct: 457 PNATIEWHWNGRKIKDLYDTNLKIVGTGPRSDLIVHPVTRQYYSGYKCIATNIHG 511



 Score = 85.4 bits (202), Expect = 8e-15
 Identities = 78/325 (24%), Positives = 124/325 (38%), Gaps = 27/325 (8%)

Query: 27  QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
           Q   + C     P+P I W + G  + +   + ++   GL           SD G+Y C 
Sbjct: 153 QDYVVMCEVKADPNPTIDWLRNGDPIRTTNDKYVVQTNGLLIRNVQ----ESDEGIYTCR 208

Query: 87  ATNSYGTARSRNATLHVAV-LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
           A     T      T+ V V ++ E    P + ++ +G      C   RG P P + W ++
Sbjct: 209 AA-VIETGELLERTIRVEVFIQPEIISLPTNLEAVEGKPFAANC-TARGKPVPEISWIRD 266

Query: 146 GQTLLFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL 204
              L      R  +    G + I    Q D G Y C+A+N AG  +     L + ++P +
Sbjct: 267 ATQLNVATADRFQVNPQTGLVTISSVSQDDYGTYTCLAKNRAGVVDQK-TKLNVLVRPQI 325

Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK-----VLD------ 253
                   A+T   +   CR  G P P + +RR         G+       +L+      
Sbjct: 326 YELYNVTGART-KEIAITCRAKGRPAPAITFRRWGTQEEYTNGQQDDDPRIILEPNFDEE 384

Query: 254 ----DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES--G 307
                G+LR+ N   +D+G Y C A N       +G++TV   P  +       V S   
Sbjct: 385 RGESTGTLRISNAERSDDGLYQCIARNKGADAYKTGHITVEFAPDFSHMKELPPVFSWEQ 444

Query: 308 NVARFTCTATGRPEPTMFWSVEGNR 332
             A  +C A G P  T+ W   G +
Sbjct: 445 RKANLSCLAMGIPNATIEWHWNGRK 469



 Score = 54.8 bits (126), Expect = 1e-05
 Identities = 53/189 (28%), Positives = 79/189 (41%), Gaps = 23/189 (12%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHR-SILPAGGLFFL 69
           P II  P ++     +P   NC A G P P I W +    L V+   R  + P  GL  +
Sbjct: 230 PEIISLPTNLEAVEGKPFAANCTARGKPVPEISWIRDATQLNVATADRFQVNPQTGLVTI 289

Query: 70  RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
            +       D G Y C A N  G    +   L+V V  + + L   +   A+   + + C
Sbjct: 290 SSVS---QDDYGTYTCLAKNRAGVV-DQKTKLNVLVRPQIYEL--YNVTGARTKEIAITC 343

Query: 130 LPPRGSPEPNVYWKKNGQTLLF-----DGDSRMHLVDG---------GNLVIQDARQTDA 175
              +G P P + +++ G    +     D D R+ L            G L I +A ++D 
Sbjct: 344 -RAKGRPAPAITFRRWGTQEEYTNGQQDDDPRIILEPNFDEERGESTGTLRISNAERSDD 402

Query: 176 GRYQCIARN 184
           G YQCIARN
Sbjct: 403 GLYQCIARN 411



 Score = 44.8 bits (101), Expect = 0.015
 Identities = 25/92 (27%), Positives = 40/92 (43%)

Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS 460
           TN P NQ   +    V  C     P P I W   G+ +   + + V     L+++++ +S
Sbjct: 141 TNAPENQYPTLGQDYVVMCEVKADPNPTIDWLRNGDPIRTTNDKYVVQTNGLLIRNVQES 200

Query: 461 DSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
           D G YTC A+      +    + V+  I P I
Sbjct: 201 DEGIYTCRAAVIETGELLERTIRVEVFIQPEI 232


>UniRef50_Q9W4Y3 Cluster: CG33950-PF, isoform F; n=13; Coelomata|Rep:
            CG33950-PF, isoform F - Drosophila melanogaster (Fruit
            fly)
          Length = 4629

 Score = 99.5 bits (237), Expect = 5e-19
 Identities = 109/403 (27%), Positives = 164/403 (40%), Gaps = 53/403 (13%)

Query: 31   LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
            LNC+     S    W   G  + S   R++   G    +R       SD+GVY C A + 
Sbjct: 3073 LNCQFTSVASLRYDWSHNGRSLSSSPARNVEIRGNTLEVRDAS---ESDSGVYTCVAYD- 3128

Query: 91   YGTARSRNATLHVAVLREE---FRLEP--ESKQS----AQGDTVVLECLPPRGSPEPNVY 141
              T R+   +  V + R E   F  +P  ES +      QG+   + C    GSP P++ 
Sbjct: 3129 VRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITC-EASGSPYPSIK 3187

Query: 142  WKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201
            W K    +       +H + G  L I  AR  + G Y C+A N  G   S +++  I I+
Sbjct: 3188 WAKVHDFM----PENVH-ISGNVLTIYGARFENRGVYSCVAENDHG---SDLSSTSIDIE 3239

Query: 202  PY------LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
            P       +++ P    +  G+  +  C V G P P V W R  G    P  R K+   G
Sbjct: 3240 PRERPSVKIVSAPLQTFS-VGAPASLYCTVEGIPDPTVEWVRVDGQPLSP--RHKIQSPG 3296

Query: 256  SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS--VNVESGNVARFT 313
             + +D++ L D G+Y C A+N VG  +    +TV +P  + + P++  + +  G+    T
Sbjct: 3297 YMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLT 3356

Query: 314  CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
            C  +G P P + W  E         + RD Y   +      +L I    K D+     C 
Sbjct: 3357 CVGSGVPNPEVEWVNE-------MALKRDLYSPPS---NTAILKIYRVTKADA-GIYTCH 3405

Query: 374  AVNYAGSSFV---------RGKLTVTSDDDRPPPIITNGPSNQ 407
              N AGS            RG +    DD    PI  N P  Q
Sbjct: 3406 GKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQ 3448



 Score = 84.6 bits (200), Expect = 1e-14
 Identities = 112/483 (23%), Positives = 187/483 (38%), Gaps = 53/483 (10%)

Query: 14   IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
            I+  P  VT   +    + C   G+P+P + W +  V   +D   +      L F     
Sbjct: 2960 IVNLPSHVTFEEYVNNEIICEVLGNPAPRVTWAR--VDGHADAQSTRTYDNRLIF----D 3013

Query: 74   GRVHSDAGVYWCEATN------SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
                SD G Y C+A N       Y     ++        ++   + PE      G++  L
Sbjct: 3014 SPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQL 3073

Query: 128  ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
             C            W  NG++ L    +R   + G  L ++DA ++D+G Y C+A +   
Sbjct: 3074 NC-QFTSVASLRYDWSHNGRS-LSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVR- 3130

Query: 188  TRESAIATLKIHI----------KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
            TR +   + +++I          KP + +  ++++   G   +  C   G P P + W +
Sbjct: 3131 TRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAK 3190

Query: 238  SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV--YDPPSI 295
                  MP   V +     L +      + G YSC AEN  G+  +S  + +   + PS+
Sbjct: 3191 V--HDFMP-ENVHI-SGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSV 3246

Query: 296  NLSPNSVNVES-GNVARFTCTATGRPEPTMFW-SVEGNRTIIFPGMSRDKYHATAVFDGV 353
             +    +   S G  A   CT  G P+PT+ W  V+G      P   R K  +       
Sbjct: 3247 KIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQ-----PLSPRHKIQSPG----- 3296

Query: 354  TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK- 412
              + I+D    DS     C A N  G +   G  T+T  +   P ++   P N+ L +  
Sbjct: 3297 -YMVIDDIQLEDS-GDYECRAKNIVGEA--TGVATITVQE---PTLVQIIPDNRDLRLTE 3349

Query: 413  -SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
                   C     P P + W  E  AL ++     +N   L +  + K+D+G YTC   +
Sbjct: 3350 GDELSLTCVGSGVPNPEVEWVNE-MALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKN 3408

Query: 472  RHG 474
              G
Sbjct: 3409 EAG 3411



 Score = 78.6 bits (185), Expect = 1e-12
 Identities = 115/502 (22%), Positives = 190/502 (37%), Gaps = 61/502 (12%)

Query: 15   IEQPLDVTVARHQPATLNC--RAGGSPSPAI-RWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            I++P    V      TL+C  R   S SP I  WYK      S    ++   GG  +L  
Sbjct: 2864 IQKPEITIVPVGGSMTLSCSGRMRWSNSPVIVNWYKEN----SRLPENVEVQGGNLYL-- 2917

Query: 72   THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
             +    SD+GVY C+A N+  TA     T+ + + +++ +L P    +        E + 
Sbjct: 2918 -YDLQVSDSGVYICQAVNNE-TASVFKDTVSITITKKD-QLSPAEIVNLPSHVTFEEYVN 2974

Query: 132  PR------GSPEPNVYWKKNGQTLLFDG--DSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
                    G+P P V W +       DG  D++        L+    R++D GRY+C A 
Sbjct: 2975 NEIICEVLGNPAPRVTWAR------VDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAE 3028

Query: 184  NAAGTRESAIATLKIHIKPY-------LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
            N     E  +        P        L   PE++    G S    C+          W 
Sbjct: 3029 NDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLRYDWS 3088

Query: 237  RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEA----------ENSVGAVSASGY 286
             +    +    R   +   +L + +   +D G Y+C A          E++   +     
Sbjct: 3089 HNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREE 3148

Query: 287  LTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHA 346
                + P I     ++ +  G     TC A+G P P++ W+   +     P    +  H 
Sbjct: 3149 QPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHD---FMP----ENVHI 3201

Query: 347  TAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN 406
            +       VLTI    + ++R    C A N  GS      + +    +RP   I + P  
Sbjct: 3202 SG-----NVLTIYGA-RFENRGVYSCVAENDHGSDLSSTSIDI-EPRERPSVKIVSAPL- 3253

Query: 407  QTLPIKSMAVFPCTAICTPEPIIAWY-FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465
            QT  + + A   CT    P+P + W   +G+ L   H+  + + G +V+ D+   DSG Y
Sbjct: 3254 QTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHK--IQSPGYMVIDDIQLEDSGDY 3311

Query: 466  TCVASSRHGKYVWSGALLVDSP 487
             C A +  G+      + V  P
Sbjct: 3312 ECRAKNIVGEATGVATITVQEP 3333



 Score = 78.2 bits (184), Expect = 1e-12
 Identities = 75/283 (26%), Positives = 121/283 (42%), Gaps = 27/283 (9%)

Query: 9    GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
            G  P I     ++ + + +  ++ C A GSP P+I+W K    +  + H S    G +  
Sbjct: 3152 GNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMPENVHIS----GNVLT 3207

Query: 69   LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS-AQGDTVVL 127
            +   +G    + GVY C A N +G+  S  +       R   ++     Q+ + G    L
Sbjct: 3208 I---YGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSAPLQTFSVGAPASL 3264

Query: 128  ECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
             C    G P+P V W + +GQ L      R  +   G +VI D +  D+G Y+C A+N  
Sbjct: 3265 YC-TVEGIPDPTVEWVRVDGQPL----SPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIV 3319

Query: 187  GTRESAIATLKIHIKPYL---ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
            G   + +AT+ +  +P L   I    D+    G  ++  C   G P P+V W        
Sbjct: 3320 G-EATGVATITVQ-EPTLVQIIPDNRDLRLTEGDELSLTCVGSGVPNPEVEW-----VNE 3372

Query: 244  MPLGR---VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSA 283
            M L R       +   L++  V  AD G Y+C  +N  G+  A
Sbjct: 3373 MALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEA 3415



 Score = 68.5 bits (160), Expect = 1e-09
 Identities = 85/358 (23%), Positives = 140/358 (39%), Gaps = 36/358 (10%)

Query: 160  VDGGNLVIQDARQTDAGRYQCIARN--AAGTRESAIA---TLKIHIKP-YLITGPEDVVA 213
            V GGNL + D + +D+G Y C A N   A   +  ++   T K  + P  ++  P  V  
Sbjct: 2910 VQGGNLYLYDLQVSDSGVYICQAVNNETASVFKDTVSITITKKDQLSPAEIVNLPSHVTF 2969

Query: 214  QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCE 273
            +   +    C V G+P P V W R  G  +    R     D  L  D+   +DEG Y C+
Sbjct: 2970 EEYVNNEIICEVLGNPAPRVTWARVDGHADAQSTRTY---DNRLIFDSPRKSDEGRYRCQ 3026

Query: 274  AENSVGAVSASGYLTVY---DPPS-------INLSPNSVNVESGNVARFTCTATGRPEPT 323
            AEN         Y+ VY   +PP        + ++P  +N  +G   +  C  T      
Sbjct: 3027 AENDQN--RDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLR 3084

Query: 324  MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR-NTIVCSAVNYAGSSF 382
              WS  G      P  + +         G T L + D  ++DS   T V   V    +  
Sbjct: 3085 YDWSHNGRSLSSSPARNVE-------IRGNT-LEVRDASESDSGVYTCVAYDVRTRRNFT 3136

Query: 383  VRGKLTVTSDDDRP---PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI 439
               ++ +   +++P    PII +   N  +         C A  +P P I W    + + 
Sbjct: 3137 ESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMP 3196

Query: 440  QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRA 497
            +N      +   L +      + G Y+CVA + HG  + S ++ ++    P++    A
Sbjct: 3197 ENVH---ISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSA 3251



 Score = 56.8 bits (131), Expect = 3e-06
 Identities = 80/327 (24%), Positives = 125/327 (38%), Gaps = 44/327 (13%)

Query: 80   AGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESK--QSAQGDTVVLECLPPRGSP 136
            AG Y C A N YG   +R+    VAV +  +F   P+S+  +  +G+ + L+C     + 
Sbjct: 3603 AGEYRCSAFNQYG---NRSQIARVAVKKPADFHQVPQSQLQRHREGENIQLQCTV---TD 3656

Query: 137  EPNVYWKKNGQTLLFDGDSRM----HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
            +  V  + N +   F  D R        D   LV+ + R  DAGRY C + +    ++  
Sbjct: 3657 QYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLP 3716

Query: 193  IATLK-------------IHIKPYLITGPEDVVAQ---------TGSSVTFQCRVGGDPL 230
              ++              I++ P L     D   +          G S   +C    D  
Sbjct: 3717 EVSIDLQVLTATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTY 3776

Query: 231  PDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY-LTV 289
             DV+W RS G    PL          L + NV  +D G Y C+ +   G +  + Y L V
Sbjct: 3777 TDVVWERSDGA---PLSNNVRQVGNRLVISNVSPSDAGNYVCKCKTDEGDLYTTSYKLEV 3833

Query: 290  YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWS-----VEGNRTIIFPGMSRDKY 344
             D P    S   V  + G  A   C A    +PT  WS     ++  R+++   +S D  
Sbjct: 3834 EDQPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSV 3893

Query: 345  HATAVFDGVTVLTINDTDKNDSRNTIV 371
             A      +      D +  D  N +V
Sbjct: 3894 QANDAGTYICTAQYADGETADFPNILV 3920



 Score = 41.5 bits (93), Expect = 0.14
 Identities = 77/333 (23%), Positives = 114/333 (34%), Gaps = 44/333 (13%)

Query: 14   IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
            II    D+ +      +L C   G P+P + W     L   D +        L   R T 
Sbjct: 3338 IIPDNRDLRLTEGDELSLTCVGSGVPNPEVEWVNEMALK-RDLYSPPSNTAILKIYRVTK 3396

Query: 74   GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
                +DAG+Y C   N  G+  +     HV V  +E R +         D   +   PP+
Sbjct: 3397 ----ADAGIYTCHGKNEAGSDEA-----HVRVEVQERRGDIGGVDD-DSDRDPINYNPPQ 3446

Query: 134  GSPEPNVYWKKNGQTLLFD-GDS-------------RMHLVDGG-----------NLVIQ 168
                P ++   + Q L  D GD+             R   VDG             L I 
Sbjct: 3447 -QQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIV 3505

Query: 169  DARQTDAGRYQCIARNAAGTRESA-IATLKIHIKPYLITGPE-DVVAQTGSSVTFQCRVG 226
               Q + G+Y+C      G  ++  +  L +   P +   P   +  + G ++   C+V 
Sbjct: 3506 RVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVEAGQNLDVHCQVE 3565

Query: 227  GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY 286
                 DV W       N PL     +    LR  ++  A  GEY C A N  G  S    
Sbjct: 3566 NVRPEDVHWSTD---NNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIAR 3622

Query: 287  LTVYDPPSINLSPNS--VNVESGNVARFTCTAT 317
            + V  P   +  P S       G   +  CT T
Sbjct: 3623 VAVKKPADFHQVPQSQLQRHREGENIQLQCTVT 3655



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 24/71 (33%), Positives = 33/71 (46%), Gaps = 3/71 (4%)

Query: 204  LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVI 263
            L T P+  + +    V F+CR  G     V W R  GG  +P G      +G L + N+ 
Sbjct: 1488 LKTYPDSQIIKESREVIFRCRDEGPARAKVKWSR-PGGRPLPPGFTD--RNGRLEIPNIR 1544

Query: 264  LADEGEYSCEA 274
            + D G Y CEA
Sbjct: 1545 VEDAGTYVCEA 1555



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 30/99 (30%), Positives = 39/99 (39%), Gaps = 9/99 (9%)

Query: 292  PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
            P  I   P SV++    V   TC ATG P PT+ W +         G   DK  + + + 
Sbjct: 1737 PLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNW-------GHVPDKCESKS-YG 1788

Query: 352  GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT 390
            G   L   D    DS     C  +N  G+ FV     VT
Sbjct: 1789 GTGTLRCPDMRPQDS-GAYSCEIINTRGTHFVNPDTIVT 1826



 Score = 35.5 bits (78), Expect = 8.9
 Identities = 20/76 (26%), Positives = 34/76 (44%), Gaps = 2/76 (2%)

Query: 419  CTAICTPEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC-VASSRHGKY 476
            C A  TP P I W    G    +   ++    GTL   D+   DSG Y+C + ++R   +
Sbjct: 1759 CVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTRGTHF 1818

Query: 477  VWSGALLVDSPINPNI 492
            V    ++   P+  ++
Sbjct: 1819 VNPDTIVTVRPVRTDV 1834


>UniRef50_UPI0000D55C03 Cluster: PREDICTED: similar to CG33484-PA;
            n=1; Tribolium castaneum|Rep: PREDICTED: similar to
            CG33484-PA - Tribolium castaneum
          Length = 3764

 Score = 99.1 bits (236), Expect = 6e-19
 Identities = 122/521 (23%), Positives = 191/521 (36%), Gaps = 48/521 (9%)

Query: 10   EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
            EAP       D  +      T  C   G+P P + W+K G+ + ++         GL  L
Sbjct: 1352 EAPVFTSPLSDAIIQEGSRFTFMCHVTGTPVPVVTWFKDGISIQNNPDYQTTFDQGLCTL 1411

Query: 70   RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-------ESKQSAQG 122
                     D+  Y C+A N+ G+A + +A L V     E +L P       E   + +G
Sbjct: 1412 TIEE-TFAEDSAKYTCKAINAAGSAET-SACLSVKETEPEEQLSPPTFVKLLEPGSAREG 1469

Query: 123  DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD-ARQTDAGRYQCI 181
                  C    G+P P V W KN + +    D  +   +G  ++  D     D   Y C 
Sbjct: 1470 AGFQFYC-KVEGNPLPTVQWFKNYECIDNSPDYVITYNNGEAILKFDKVSLEDKAEYTCK 1528

Query: 182  ARNAAGTRESA----IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
            A N  G  +S     +  L+    P  I    +V+A+ G  +  +C V G P P + W  
Sbjct: 1529 ATNELGVAQSTASLTVTPLEPTEAPKFILPLSNVMARAGQKIKLECEVSGLPPPILTWTH 1588

Query: 238  SAGGGNMPLGRVKVL-------DDGSLRLDNVILADEGEYSCEAE---NSVGAVSASGYL 287
            +         +  +L       D G+  ++   +A E   +C            S S   
Sbjct: 1589 NGKALQFEGNKATLLVFEAFPKDAGTYVVNAKNIAGEASSACSVSVKGRLPTETSDSELA 1648

Query: 288  TVYDP--PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345
            +  +P  PSI L   +V+V  GN  R  C   G+PEP + W    +R +      ++   
Sbjct: 1649 SDMEPVKPSIQLPLTNVSVTEGNRVRLDCVIVGQPEPEVIW-YHDDRPV------KESPD 1701

Query: 346  ATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPS 405
               +F G     I      +        A+N AG +  +  LTV  D    PP     P 
Sbjct: 1702 FQLLFQGDRCSLIIQEALPEDAGQYKVVALNSAGEASSKCSLTVVPDSGTKPPEPEEPPG 1761

Query: 406  NQ---TLPIKSMAV-------FPCTAICTPEPIIAWYFEGEALIQNHRRNVT--NDGTLV 453
                 T  +  + V       F       P P I W    + +       +T  +DGT+ 
Sbjct: 1762 TPPKFTKLLSDVLVSEGEKVEFEGCVTGEPTPEIKWLLNNQPITPTDHVKITHNSDGTIR 1821

Query: 454  LK--DLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
            L+  ++   D G YT  A++  G       L+V S   P I
Sbjct: 1822 LEIANVRPEDKGVYTVKATNSSGDAKCFAQLIVKSMKPPEI 1862



 Score = 69.3 bits (162), Expect = 6e-10
 Identities = 135/540 (25%), Positives = 202/540 (37%), Gaps = 73/540 (13%)

Query: 15   IEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
            I+ PL +V+V       L+C   G P P + WY     V       +L  G    L    
Sbjct: 1658 IQLPLTNVSVTEGNRVRLDCVIVGQPEPEVIWYHDDRPVKESPDFQLLFQGDRCSLIIQE 1717

Query: 74   GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS-------------- 119
              +  DAG Y   A NS G A S+  +L V         EPE                  
Sbjct: 1718 A-LPEDAGQYKVVALNSAGEASSK-CSLTVVPDSGTKPPEPEEPPGTPPKFTKLLSDVLV 1775

Query: 120  AQGDTVVLE-CLPPRGSPEPNVYWKKNGQTLL-FDGDSRMHLVDGG-NLVIQDARQTDAG 176
            ++G+ V  E C+   G P P + W  N Q +   D     H  DG   L I + R  D G
Sbjct: 1776 SEGEKVEFEGCVT--GEPTPEIKWLLNNQPITPTDHVKITHNSDGTIRLEIANVRPEDKG 1833

Query: 177  RYQCIARNAAGTRESAIATLKIHIKPYLI-------TGPE------DVVAQTGSSVTFQC 223
             Y   A N++G  +     +   +KP  I       +GP       D VA  G+S  F+C
Sbjct: 1834 VYTVKATNSSGDAKCFAQLIVKSMKPPEIIKHEEIKSGPSFKELFNDRVAFEGTSTKFEC 1893

Query: 224  RVGGDPLPDVLWRRSAGGGNMPLGRVKVL-----DDGSLRLDNVILADEGEYSCEAENSV 278
             V G P P V W      G    GR K+L     D   L +  +    EG  +C AEN V
Sbjct: 1894 IVVGKPTPKVRW---LFNGEPITGR-KILISTSGDRQVLTIPEISKDLEGTITCVAENEV 1949

Query: 279  GAVSASGYLTVYDPPSINL----SPNSVNVESG-----NVARFTCTATGRPEPTMFWSVE 329
            G  S + +L+V    +I L       S +VES       V   + T+T R   T F   +
Sbjct: 1950 GKASCAAHLSVQSVSTITLPEFSRDISQHVESSYILNREVHTQSSTSTSRKMET-FTGTQ 2008

Query: 330  GNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI---VCSAVNYAGSSFVRGK 386
              +  +     +D+     +        I+++ K +  + +     + +  + S F  G 
Sbjct: 2009 EPQVQVHSFSQKDQQSFKQI--NQEAPQISESHKIEEYHQVGKQPPTIIEKSSSLFTTGT 2066

Query: 387  LTVTSDDDRP----PPIITNGPSNQTLPIKSMAV-----FPCTAICTPEPI--IAWYFEG 435
               T           P+I   P     P+    V          I   +P   I W   G
Sbjct: 2067 TEETKQKTIEHVVHKPVIKTRPPKFITPVMGKIVDQNVDVVLEGIVDGQPTPEITWTKNG 2126

Query: 436  EALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
            E L ++    +    N  ++V+K+    D+G YTC A +  GK + +  L+V   + P +
Sbjct: 2127 EQLRESSGVQIHFDRNKVSVVIKNATIDDAGRYTCTAVNEAGKAISTADLVVRKTVFPPV 2186



 Score = 61.7 bits (143), Expect = 1e-07
 Identities = 51/179 (28%), Positives = 77/179 (43%), Gaps = 8/179 (4%)

Query: 121  QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQ 179
            Q   VVLE +   G P P + W KNG+ L      ++H      ++VI++A   DAGRY 
Sbjct: 2102 QNVDVVLEGIVD-GQPTPEITWTKNGEQLRESSGVQIHFDRNKVSVVIKNATIDDAGRYT 2160

Query: 180  CIARNAAGTRESA--IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
            C A N AG   S   +   K    P      +  V + G  V  +  V G P P V W +
Sbjct: 2161 CTAVNEAGKAISTADLVVRKTVFPPVFGRRLQAQVVKKGDRVIMEVEVTGTPDPTVTWYK 2220

Query: 238  SAGGGNMPLG---RVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
                    LG   R++ + +  +L ++   L   G +   A NS G   +   + V++P
Sbjct: 2221 DGVPIGEALGDKARIRSMGNSHTLVIEKAELNMSGRFMVRAVNSGGEAQSIADIAVFEP 2279



 Score = 51.6 bits (118), Expect = 1e-04
 Identities = 28/78 (35%), Positives = 40/78 (51%), Gaps = 3/78 (3%)

Query: 122  GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQC 180
            G     EC+  +  P PN+ W KNG+ +    D ++H  +G   L I  A   DAG Y C
Sbjct: 3590 GQPAKFECIV-QSEPPPNILWSKNGRIIENSNDYQLHYRNGVCRLTISQAYPEDAGTYAC 3648

Query: 181  IARNAAGTRESAIATLKI 198
             A N+ GT  +  ATL++
Sbjct: 3649 TATNSVGT-VNTTATLEV 3665



 Score = 51.2 bits (117), Expect = 2e-04
 Identities = 32/97 (32%), Positives = 42/97 (43%), Gaps = 2/97 (2%)

Query: 7    TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66
            +S  AP  I    ++ V   QPA   C     P P I W K G ++ +     +    G+
Sbjct: 3571 SSARAPMFITPLRNIAVVSGQPAKFECIVQSEPPPNILWSKNGRIIENSNDYQLHYRNGV 3630

Query: 67   FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103
              L  +      DAG Y C ATNS GT  +  ATL V
Sbjct: 3631 CRLTISQA-YPEDAGTYACTATNSVGTVNT-TATLEV 3665



 Score = 50.8 bits (116), Expect = 2e-04
 Identities = 47/184 (25%), Positives = 76/184 (41%), Gaps = 6/184 (3%)

Query: 12   PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
            P  I   +   V ++    L     G P+P I W K G  +   +   I        +  
Sbjct: 2089 PKFITPVMGKIVDQNVDVVLEGIVDGQPTPEITWTKNGEQLRESSGVQIHFDRNKVSVVI 2148

Query: 72   THGRVHSDAGVYWCEATNSYGTARS-RNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
             +  +  DAG Y C A N  G A S  +  +   V    F    +++   +GD V++E +
Sbjct: 2149 KNATI-DDAGRYTCTAVNEAGKAISTADLVVRKTVFPPVFGRRLQAQVVKKGDRVIME-V 2206

Query: 131  PPRGSPEPNVYWKKNGQTL---LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
               G+P+P V W K+G  +   L D      + +   LVI+ A    +GR+   A N+ G
Sbjct: 2207 EVTGTPDPTVTWYKDGVPIGEALGDKARIRSMGNSHTLVIEKAELNMSGRFMVRAVNSGG 2266

Query: 188  TRES 191
              +S
Sbjct: 2267 EAQS 2270



 Score = 46.8 bits (106), Expect = 0.004
 Identities = 36/138 (26%), Positives = 54/138 (39%), Gaps = 13/138 (9%)

Query: 202  PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR------RSAGGGNMPLGRVKVLDDG 255
            P  IT     +      V  +  V G P P++ W       R + G  +   R KV    
Sbjct: 2089 PKFITPVMGKIVDQNVDVVLEGIVDGQPTPEITWTKNGEQLRESSGVQIHFDRNKV---- 2144

Query: 256  SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLSPNSVNVESGNVARF 312
            S+ + N  + D G Y+C A N  G   ++  L V     PP       +  V+ G+    
Sbjct: 2145 SVVIKNATIDDAGRYTCTAVNEAGKAISTADLVVRKTVFPPVFGRRLQAQVVKKGDRVIM 2204

Query: 313  TCTATGRPEPTMFWSVEG 330
                TG P+PT+ W  +G
Sbjct: 2205 EVEVTGTPDPTVTWYKDG 2222



 Score = 45.6 bits (103), Expect = 0.008
 Identities = 55/216 (25%), Positives = 82/216 (37%), Gaps = 21/216 (9%)

Query: 9    GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL-PAGGLF 67
            G  P   +   DV V+  +         G P+P I+W      +    H  I   + G  
Sbjct: 1761 GTPPKFTKLLSDVLVSEGEKVEFEGCVTGEPTPEIKWLLNNQPITPTDHVKITHNSDGTI 1820

Query: 68   FLRATHGRVHSDAGVYWCEATNSYGTARS------RNATLHVAVLREEFRLEPESKQ--- 118
             L   + R   D GVY  +ATNS G A+       ++      +  EE +  P  K+   
Sbjct: 1821 RLEIANVR-PEDKGVYTVKATNSSGDAKCFAQLIVKSMKPPEIIKHEEIKSGPSFKELFN 1879

Query: 119  ---SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQT 173
               + +G +   EC+   G P P V W  NG+ +   G   +    G    L I +  + 
Sbjct: 1880 DRVAFEGTSTKFECIVV-GKPTPKVRWLFNGEPI--TGRKILISTSGDRQVLTIPEISKD 1936

Query: 174  DAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
              G   C+A N  G + S  A L +      IT PE
Sbjct: 1937 LEGTITCVAENEVG-KASCAAHLSVQ-SVSTITLPE 1970



 Score = 43.6 bits (98), Expect = 0.034
 Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 2/95 (2%)

Query: 202  PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL-- 259
            P  IT   ++   +G    F+C V  +P P++LW ++               +G  RL  
Sbjct: 3576 PMFITPLRNIAVVSGQPAKFECIVQSEPPPNILWSKNGRIIENSNDYQLHYRNGVCRLTI 3635

Query: 260  DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
                  D G Y+C A NSVG V+ +  L V   PS
Sbjct: 3636 SQAYPEDAGTYACTATNSVGTVNTTATLEVPGVPS 3670



 Score = 43.2 bits (97), Expect = 0.044
 Identities = 40/163 (24%), Positives = 63/163 (38%), Gaps = 14/163 (8%)

Query: 318  GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
            G+P P + W+  G +        R+       FD   V  +      D      C+AVN 
Sbjct: 2114 GQPTPEITWTKNGEQL-------RESSGVQIHFDRNKVSVVIKNATIDDAGRYTCTAVNE 2166

Query: 378  AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFE--- 434
            AG +     L V       PP+       Q +      +       TP+P + WY +   
Sbjct: 2167 AGKAISTADLVVRKTVF--PPVFGRRLQAQVVKKGDRVIMEVEVTGTPDPTVTWYKDGVP 2224

Query: 435  -GEALIQNHR-RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
             GEAL    R R++ N  TLV++  + + SG +   A +  G+
Sbjct: 2225 IGEALGDKARIRSMGNSHTLVIEKAELNMSGRFMVRAVNSGGE 2267



 Score = 35.5 bits (78), Expect = 8.9
 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 7/80 (8%)

Query: 301  SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
            ++ V SG  A+F C     P P + WS  G    I    +  + H     +GV  LTI+ 
Sbjct: 3584 NIAVVSGQPAKFECIVQSEPPPNILWSKNGR---IIENSNDYQLHYR---NGVCRLTISQ 3637

Query: 361  TDKNDSRNTIVCSAVNYAGS 380
                D+  T  C+A N  G+
Sbjct: 3638 AYPEDA-GTYACTATNSVGT 3656


>UniRef50_A7SQE0 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 178

 Score = 99.1 bits (236), Expect = 6e-19
 Identities = 58/180 (32%), Positives = 94/180 (52%), Gaps = 12/180 (6%)

Query: 20  DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
           ++T+   + A L C A GSP+P  RW K G  +      S++ AGG   + +T   + SD
Sbjct: 7   NLTLIAGETAVLQCTAAGSPTPYFRWLKSGKSLTMGGRMSVI-AGGSLMIEST---MASD 62

Query: 80  AGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
              Y C+A N+ G+    +  +++ V+          S    QGDT+ L C   +G P P
Sbjct: 63  EANYTCQAVNNVGSV---HMAIYLEVIGPPNITSFRSSVTGVQGDTISLPCRA-KGFPPP 118

Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
            + W ++GQT+ +D   R   +D G L+I + +++D+G+Y C A N AG R+S   T+ I
Sbjct: 119 VITWSRSGQTIPYD---RRQSIDNGTLLIGNVQKSDSGKYTCTAVNTAGERDSVTMTVSI 175



 Score = 97.5 bits (232), Expect = 2e-18
 Identities = 55/158 (34%), Positives = 85/158 (53%), Gaps = 6/158 (3%)

Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
           G+T VL+C    GSP P   W K+G++L   G  RM ++ GG+L+I+    +D   Y C 
Sbjct: 13  GETAVLQCTAA-GSPTPYFRWLKSGKSLTMGG--RMSVIAGGSLMIESTMASDEANYTCQ 69

Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
           A N  G+   AI  L++   P + +    V    G +++  CR  G P P + W RS  G
Sbjct: 70  AVNNVGSVHMAIY-LEVIGPPNITSFRSSVTGVQGDTISLPCRAKGFPPPVITWSRS--G 126

Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279
             +P  R + +D+G+L + NV  +D G+Y+C A N+ G
Sbjct: 127 QTIPYDRRQSIDNGTLLIGNVQKSDSGKYTCTAVNTAG 164



 Score = 89.0 bits (211), Expect = 7e-16
 Identities = 60/175 (34%), Positives = 85/175 (48%), Gaps = 15/175 (8%)

Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAE 275
           G +   QC   G P P   W +S     M  GR+ V+  GSL +++ + +DE  Y+C+A 
Sbjct: 13  GETAVLQCTAAGSPTPYFRWLKSGKSLTMG-GRMSVIAGGSLMIESTMASDEANYTCQAV 71

Query: 276 NSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII 335
           N+VG+V  + YL V  PP+I    +SV    G+     C A G P P + WS  G +TI 
Sbjct: 72  NNVGSVHMAIYLEVIGPPNITSFRSSVTGVQGDTISLPCRAKGFPPPVITWSRSG-QTI- 129

Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT 390
                   Y      D  T+L I +  K+DS     C+AVN AG    R  +T+T
Sbjct: 130 -------PYDRRQSIDNGTLL-IGNVQKSDS-GKYTCTAVNTAGE---RDSVTMT 172



 Score = 70.9 bits (166), Expect = 2e-10
 Identities = 55/176 (31%), Positives = 81/176 (46%), Gaps = 16/176 (9%)

Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
           +++ + +G  A   CTA G P P   W   G    +   MS        V  G +++ I 
Sbjct: 6   HNLTLIAGETAVLQCTAAGSPTPYFRWLKSGKSLTMGGRMS--------VIAGGSLM-IE 56

Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419
            T  +D  N   C AVN  GS  +   L V       PP IT+  S+ T         PC
Sbjct: 57  STMASDEAN-YTCQAVNNVGSVHMAIYLEVIG-----PPNITSFRSSVTGVQGDTISLPC 110

Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
            A   P P+I W   G+ +  + R+++ N GTL++ ++ KSDSG YTC A +  G+
Sbjct: 111 RAKGFPPPVITWSRSGQTIPYDRRQSIDN-GTLLIGNVQKSDSGKYTCTAVNTAGE 165



 Score = 51.2 bits (117), Expect = 2e-04
 Identities = 32/93 (34%), Positives = 44/93 (47%), Gaps = 2/93 (2%)

Query: 406 NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465
           N TL     AV  CTA  +P P   W   G++L    R +V   G+L+++    SD   Y
Sbjct: 7   NLTLIAGETAVLQCTAAGSPTPYFRWLKSGKSLTMGGRMSVIAGGSLMIESTMASDEANY 66

Query: 466 TCVASSRHGKYVWSGALLVDSPINPNIHFFRAA 498
           TC A +  G    +  L V  P  PNI  FR++
Sbjct: 67  TCQAVNNVGSVHMAIYLEVIGP--PNITSFRSS 97



 Score = 40.7 bits (91), Expect = 0.24
 Identities = 31/93 (33%), Positives = 40/93 (43%), Gaps = 7/93 (7%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P I      VT  +    +L CRA G P P I W + G  +  D  +SI   G L     
Sbjct: 89  PNITSFRSSVTGVQGDTISLPCRAKGFPPPVITWSRSGQTIPYDRRQSI-DNGTLLI--- 144

Query: 72  THGRVH-SDAGVYWCEATNSYGTARSRNATLHV 103
             G V  SD+G Y C A N+ G   S   T+ +
Sbjct: 145 --GNVQKSDSGKYTCTAVNTAGERDSVTMTVSI 175


>UniRef50_Q9P2J2 Cluster: Protein turtle homolog A precursor; n=25;
           Tetrapoda|Rep: Protein turtle homolog A precursor - Homo
           sapiens (Human)
          Length = 1179

 Score = 99.1 bits (236), Expect = 6e-19
 Identities = 122/486 (25%), Positives = 187/486 (38%), Gaps = 53/486 (10%)

Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
           + V L C+  RGSP P+V WK  G+ L   G  ++  V  G L I+   +  +G Y C A
Sbjct: 152 EPVTLRCVA-RGSPLPHVTWKLRGKDL-GQGQGQVQ-VQNGTLRIRRVERGSSGVYTCQA 208

Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRR---S 238
            +  G+   A   L +   P ++  P++        V+  C     P      W +   +
Sbjct: 209 SSTEGSATHATQLLVLG-PPVIVVPPKNSTVNASQDVSLACHAEAYPANLTYSWFQDNIN 267

Query: 239 AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSV-GAVSASGYLTVYDPPSINL 297
               +    RV++L DGSLRL      D G Y+C   N +    SAS YLTV  P  +  
Sbjct: 268 VFHISRLQPRVRILVDGSLRLLATQPDDAGCYTCVPSNGLLHPPSASAYLTVLYPAQVTA 327

Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMF--WSVEGNRTII--FPGMSRDKYHATAVFDGV 353
            P    +  G      C     P P +F  W+ +G    +  FPG S+         +G 
Sbjct: 328 MPPETPLPIGMPGVIRCPVRANP-PLLFVSWTKDGKALQLDKFPGWSQGT-------EGS 379

Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP-IK 412
            ++ + +    D+     C+  N  G++   G   VT    + PP     P  +    + 
Sbjct: 380 LIIALGN---EDALGEYSCTPYNSLGTA---GPSPVTRVLLKAPPAFIERPKEEYFQEVG 433

Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
              + PC+A   P P+++W   G  L    +  V ++ +L+L+ L K   G + C AS+ 
Sbjct: 434 RELLIPCSAQGDPPPVVSWTKVGRGL--QGQAQVDSNSSLILRPLTKEAHGHWECSASNA 491

Query: 473 HGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGS 532
             +   S  + V   +  + H      V +LP                 +SW      G 
Sbjct: 492 VARVATSTNVYV---LGTSPHVVTNVSVVALP-------------KGANVSWEP----GF 531

Query: 533 SSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENS 592
               GY        T       R    WV +A  V   H +V  L P   Y F V  +N 
Sbjct: 532 DG--GYLQRFSVWYTPLAKRPDRMHHDWVSLAVPVGAAHLLVPGLQPHTQYQFSVLAQNK 589

Query: 593 HGLSGP 598
            G SGP
Sbjct: 590 LG-SGP 594



 Score = 77.4 bits (182), Expect = 2e-12
 Identities = 74/279 (26%), Positives = 109/279 (39%), Gaps = 13/279 (4%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSP-AIRWYKGGVLVVSDTH---RSILPAGGLF 67
           P I+  P + TV   Q  +L C A   P+     W++  + V   +    R  +   G  
Sbjct: 227 PVIVVPPKNSTVNASQDVSLACHAEAYPANLTYSWFQDNINVFHISRLQPRVRILVDGSL 286

Query: 68  FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
            L AT      DAG Y C  +N      S +A L V    +   + PE+     G   V+
Sbjct: 287 RLLATQP---DDAGCYTCVPSNGLLHPPSASAYLTVLYPAQVTAMPPETPLPI-GMPGVI 342

Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
            C      P   V W K+G+ L  D          G+L+I    +   G Y C   N+ G
Sbjct: 343 RCPVRANPPLLFVSWTKDGKALQLDKFPGWSQGTEGSLIIALGNEDALGEYSCTPYNSLG 402

Query: 188 TR-ESAIATLKIHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
           T   S +  + +   P  I  P E+   + G  +   C   GDP P V W +   G    
Sbjct: 403 TAGPSPVTRVLLKAPPAFIERPKEEYFQEVGRELLIPCSAQGDPPPVVSWTKVGRGLQ-- 460

Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSAS 284
            G+ +V  + SL L  +     G + C A N+V  V+ S
Sbjct: 461 -GQAQVDSNSSLILRPLTKEAHGHWECSASNAVARVATS 498



 Score = 75.8 bits (178), Expect = 7e-12
 Identities = 94/372 (25%), Positives = 151/372 (40%), Gaps = 36/372 (9%)

Query: 122 GDTVVLEC--LPPRGSPEPNVY-WKKNGQTL-LF----------DGD--SRMHLVDGGNL 165
           G++VVL C  LPP G P  +V  W + G  L +F          D D   R+ L  G +L
Sbjct: 34  GESVVLGCDLLPPAGRPPLHVIEWLRFGFLLPIFIQFGLYSPRIDPDYVGRVRLQKGASL 93

Query: 166 VIQDARQTDAGRYQC-IARNAAGTRESAIAT-----LKIHIKP-YLITGPEDVVAQTGSS 218
            I+  R  D G Y+C +        E   A      L ++  P +  T P  +  Q    
Sbjct: 94  QIEGLRVEDQGWYECRVFFLDQHIPEDDFANGSWVHLTVNSPPQFQETPPAVLEVQELEP 153

Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSV 278
           VT +C   G PLP V W+          G+V+V  +G+LR+  V     G Y+C+A ++ 
Sbjct: 154 VTLRCVARGSPLPHVTWKLRGKDLGQGQGQVQV-QNGTLRIRRVERGSSGVYTCQASSTE 212

Query: 279 GAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPG 338
           G+ + +  L V  PP I + P +  V +       C A   P    +   + N  +    
Sbjct: 213 GSATHATQLLVLGPPVIVVPPKNSTVNASQDVSLACHAEAYPANLTYSWFQDNINVFH-- 270

Query: 339 MSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398
           +SR +     + DG   L     D       +  + + +  S+     LTV       P 
Sbjct: 271 ISRLQPRVRILVDGSLRLLATQPDDAGCYTCVPSNGLLHPPSA--SAYLTVLY-----PA 323

Query: 399 IITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGEALIQNHRRNVT--NDGTLVLK 455
            +T  P    LPI    V  C     P  + ++W  +G+AL  +     +   +G+L++ 
Sbjct: 324 QVTAMPPETPLPIGMPGVIRCPVRANPPLLFVSWTKDGKALQLDKFPGWSQGTEGSLIIA 383

Query: 456 DLDKSDSGTYTC 467
             ++   G Y+C
Sbjct: 384 LGNEDALGEYSC 395



 Score = 72.9 bits (171), Expect = 5e-11
 Identities = 83/336 (24%), Positives = 127/336 (37%), Gaps = 18/336 (5%)

Query: 5   YVTSGEAPYIIEQPLDVT-VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
           ++T    P   E P  V  V   +P TL C A GSP P + W   G  +     +  +  
Sbjct: 129 HLTVNSPPQFQETPPAVLEVQELEPVTLRCVARGSPLPHVTWKLRGKDLGQGQGQVQVQN 188

Query: 64  GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
           G L   R   G     +GVY C+A+++ G+A   +AT  + +      + P++       
Sbjct: 189 GTLRIRRVERG----SSGVYTCQASSTEGSA--THATQLLVLGPPVIVVPPKNSTVNASQ 242

Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDG--DSRMHLVDGGNLVIQDARQTDAGRYQCI 181
            V L C            W ++   +        R+ ++  G+L +   +  DAG Y C+
Sbjct: 243 DVSLACHAEAYPANLTYSWFQDNINVFHISRLQPRVRILVDGSLRLLATQPDDAGCYTCV 302

Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLWRRSAG 240
             N      SA A L +     +   P +     G     +C V    PL  V W +   
Sbjct: 303 PSNGLLHPPSASAYLTVLYPAQVTAMPPETPLPIGMPGVIRCPVRANPPLLFVSWTKD-- 360

Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADE---GEYSCEAENSVGAVSASGYLTVY--DPPSI 295
           G  + L +      G+     + L +E   GEYSC   NS+G    S    V    PP+ 
Sbjct: 361 GKALQLDKFPGWSQGTEGSLIIALGNEDALGEYSCTPYNSLGTAGPSPVTRVLLKAPPAF 420

Query: 296 NLSPNSVNV-ESGNVARFTCTATGRPEPTMFWSVEG 330
              P      E G      C+A G P P + W+  G
Sbjct: 421 IERPKEEYFQEVGRELLIPCSAQGDPPPVVSWTKVG 456



 Score = 54.8 bits (126), Expect = 1e-05
 Identities = 60/239 (25%), Positives = 97/239 (40%), Gaps = 28/239 (11%)

Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEA----ENSVGAVSASG---YLTVYDPPSINLS 298
           +GRV++    SL+++ + + D+G Y C      ++      A+G   +LTV  PP    +
Sbjct: 82  VGRVRLQKGASLQIEGLRVEDQGWYECRVFFLDQHIPEDDFANGSWVHLTVNSPPQFQET 141

Query: 299 PNSV-NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
           P +V  V+        C A G P P + W + G       G  + +     V +G   L 
Sbjct: 142 PPAVLEVQELEPVTLRCVARGSPLPHVTWKLRGKDL----GQGQGQVQ---VQNGT--LR 192

Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
           I   ++  S     C A +  GS+    +L V       PP+I   P N T+        
Sbjct: 193 IRRVERGSS-GVYTCQASSTEGSATHATQLLVLG-----PPVIVVPPKNSTVNASQDVSL 246

Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRR-----NVTNDGTLVLKDLDKSDSGTYTCVASS 471
            C A   P  +   +F+    + +  R      +  DG+L L      D+G YTCV S+
Sbjct: 247 ACHAEAYPANLTYSWFQDNINVFHISRLQPRVRILVDGSLRLLATQPDDAGCYTCVPSN 305



 Score = 48.8 bits (111), Expect = 9e-04
 Identities = 34/112 (30%), Positives = 50/112 (44%), Gaps = 6/112 (5%)

Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG 435
           ++A  S+V   LTV S    PP      P+   +         C A  +P P + W   G
Sbjct: 121 DFANGSWVH--LTVNS----PPQFQETPPAVLEVQELEPVTLRCVARGSPLPHVTWKLRG 174

Query: 436 EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
           + L Q   +    +GTL ++ +++  SG YTC ASS  G    +  LLV  P
Sbjct: 175 KDLGQGQGQVQVQNGTLRIRRVERGSSGVYTCQASSTEGSATHATQLLVLGP 226


>UniRef50_UPI00015B59DF Cluster: PREDICTED: similar to turtle
           protein; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to turtle protein - Nasonia vitripennis
          Length = 1402

 Score = 98.7 bits (235), Expect = 8e-19
 Identities = 83/334 (24%), Positives = 143/334 (42%), Gaps = 23/334 (6%)

Query: 162 GGNLVIQDARQTDAGRYQC----IARNAAGTRESAIATLKIHIKPYLITGPEDVV-AQTG 216
           G +L + + +++D G Y+C    + R+    +      L +H  P     PE+++    G
Sbjct: 266 GASLNLTNIQESDQGWYECKVVFLNRSPNNNKNGTWFHLDVHAPPRFTITPEEMIYVNLG 325

Query: 217 SSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAE 275
            ++   C+  G P P++LW + A     P   V +++DG+ LR+  +   D G+Y+C A 
Sbjct: 326 DAIILNCQAEGTPTPEILWYKDANPVE-PSSTVTIINDGTELRISTIKTEDIGDYTCLAR 384

Query: 276 NSVGAVSASGYLTVYDPPSINLSP-NSVNVESGNVARFTCTATGRP-EPTMFWSVEGNRT 333
           N  G +S +  + +     I + P N   +E  NV  F C A   P   T+ W  EG   
Sbjct: 385 NGEGQISHTARVIIAGGAVITIPPQNETKLEGENVV-FPCEAKALPGNVTVSWYREG--- 440

Query: 334 IIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
                +S     A+   DG   L IN    +DS  T +C+  N  G             +
Sbjct: 441 APISEVSELDTRASVRMDG--SLAINPVSADDS-GTYLCTVSNGIGEPQTASAYL----N 493

Query: 394 DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN---VTNDG 450
              P  +T  P+ Q LP +   V  C     P      + + + L++ ++     V  +G
Sbjct: 494 VEYPAKVTFNPTVQYLPFRMAGVVQCYIKANPPLQYVTWTKDKRLLEPYQVKDIVVMGNG 553

Query: 451 TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
           +L+   ++++  G YTC   + HG    SG + V
Sbjct: 554 SLLFTRVNENHHGQYTCTPYNAHGTQGSSGYMEV 587



 Score = 94.7 bits (225), Expect = 1e-17
 Identities = 119/466 (25%), Positives = 185/466 (39%), Gaps = 45/466 (9%)

Query: 39  PSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN-SYGTARSR 97
           P+ +   Y+G V  VS       P GG   L  T+ +  SD G Y C+    +     ++
Sbjct: 244 PTHSGEGYEGRVAKVSPNS----PYGGAS-LNLTNIQ-ESDQGWYECKVVFLNRSPNNNK 297

Query: 98  NAT-LHVAV-LREEFRLEPESKQSAQ-GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGD 154
           N T  H+ V     F + PE       GD ++L C    G+P P + W K+   +  +  
Sbjct: 298 NGTWFHLDVHAPPRFTITPEEMIYVNLGDAIILNC-QAEGTPTPEILWYKDANPV--EPS 354

Query: 155 SRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVA 213
           S + ++ DG  L I   +  D G Y C+ARN  G + S  A + I     +   P++   
Sbjct: 355 STVTIINDGTELRISTIKTEDIGDYTCLARNGEG-QISHTARVIIAGGAVITIPPQNETK 413

Query: 214 QTGSSVTFQCRVGGDP-LPDVLWRRSAGGGNMPLGRVKVLD-------DGSLRLDNVILA 265
             G +V F C     P    V W R       P+  V  LD       DGSL ++ V   
Sbjct: 414 LEGENVVFPCEAKALPGNVTVSWYREGA----PISEVSELDTRASVRMDGSLAINPVSAD 469

Query: 266 DEGEYSCEAENSVGAV-SASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTM 324
           D G Y C   N +G   +AS YL V  P  +  +P    +         C     P P  
Sbjct: 470 DSGTYLCTVSNGIGEPQTASAYLNVEYPAKVTFNPTVQYLPFRMAGVVQCYIKANP-PLQ 528

Query: 325 FWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR 384
           + +   ++ ++ P   +D      V    ++L     + +  + T  C+  N  G+    
Sbjct: 529 YVTWTKDKRLLEPYQVKD----IVVMGNGSLLFTRVNENHHGQYT--CTPYNAHGTQGSS 582

Query: 385 GKLTVTSDDDRPPPIITNGPSNQ-TLPIKSMAVFPCTA---ICTPEPIIAWYF-EGEALI 439
           G + V     R PP+ T  P       +       C A     T +P + W   +GE L 
Sbjct: 583 GYMEVLV---RNPPVFTVEPQPMYQRKVGETVEMHCAAQESSGTQKPTVTWQRKDGEELA 639

Query: 440 QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485
           +   + V   G L +++L + D G Y CV S+     V S  L+V+
Sbjct: 640 RGRAKVV--GGNLTIENLKQQDFGVYECVVSNEVATIVKSTHLIVE 683



 Score = 87.4 bits (207), Expect = 2e-15
 Identities = 79/306 (25%), Positives = 126/306 (41%), Gaps = 15/306 (4%)

Query: 31  LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
           LNC+A G+P+P I WYK    V   +  +I+  G    LR +  +   D G Y C A N 
Sbjct: 330 LNCQAEGTPTPEILWYKDANPVEPSSTVTIINDG--TELRISTIKT-EDIGDYTCLARNG 386

Query: 91  YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL- 149
            G   S  A + +A       + P+++   +G+ VV  C          V W + G  + 
Sbjct: 387 EGQI-SHTARVIIAG-GAVITIPPQNETKLEGENVVFPCEAKALPGNVTVSWYREGAPIS 444

Query: 150 -LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208
            + + D+R  +   G+L I      D+G Y C   N  G  ++A A L +     +   P
Sbjct: 445 EVSELDTRASVRMDGSLAINPVSADDSGTYLCTVSNGIGEPQTASAYLNVEYPAKVTFNP 504

Query: 209 EDVVAQTGSSVTFQCRV-GGDPLPDVLWRRSAG-GGNMPLGRVKVLDDGSLRLDNVILAD 266
                    +   QC +    PL  V W +         +  + V+ +GSL    V    
Sbjct: 505 TVQYLPFRMAGVVQCYIKANPPLQYVTWTKDKRLLEPYQVKDIVVMGNGSLLFTRVNENH 564

Query: 267 EGEYSCEAENSVGAVSASGYLTVY--DPPSINLSPNSV-NVESGNVARFTCTA---TGRP 320
            G+Y+C   N+ G   +SGY+ V   +PP   + P  +   + G      C A   +G  
Sbjct: 565 HGQYTCTPYNAHGTQGSSGYMEVLVRNPPVFTVEPQPMYQRKVGETVEMHCAAQESSGTQ 624

Query: 321 EPTMFW 326
           +PT+ W
Sbjct: 625 KPTVTW 630



 Score = 63.3 bits (147), Expect = 4e-08
 Identities = 58/237 (24%), Positives = 98/237 (41%), Gaps = 15/237 (6%)

Query: 60  ILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESK- 117
           ++  G L F R      H   G Y C   N++GT  S +  + V V     F +EP+   
Sbjct: 549 VMGNGSLLFTRVNENH-H---GQYTCTPYNAHGTQGS-SGYMEVLVRNPPVFTVEPQPMY 603

Query: 118 QSAQGDTVVLECLPPR--GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175
           Q   G+TV + C      G+ +P V W++     L  G ++   V GGNL I++ +Q D 
Sbjct: 604 QRKVGETVEMHCAAQESSGTQKPTVTWQRKDGEELARGRAK---VVGGNLTIENLKQQDF 660

Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP---LPD 232
           G Y+C+  N   T   +   +    +P+       V  Q   ++++Q    G P      
Sbjct: 661 GVYECVVSNEVATIVKSTHLIVEGTQPHAPHNVTGVADQFSVTLSWQPGYSGGPDYKQDY 720

Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
            +W R  G        V      ++ +  +      E+    +N++G   +SG +TV
Sbjct: 721 TIWHREEGAQEWKTIPVTPSGSTTVTISRLKSGTNHEFQVVGKNALGDGMSSGIITV 777


>UniRef50_Q4T1M4 Cluster: Chromosome undetermined SCAF10538, whole
           genome shotgun sequence; n=9; Euteleostomi|Rep:
           Chromosome undetermined SCAF10538, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 2293

 Score = 98.7 bits (235), Expect = 8e-19
 Identities = 90/326 (27%), Positives = 131/326 (40%), Gaps = 21/326 (6%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI----LPAGGLF 67
           P I+    +  V  ++P  L C   G+P P   W      V+ D+H  +       G + 
Sbjct: 450 PKILSSFSEKVVNPNEPVFLVCNVKGTPPPRCSWSLDDDPVIKDSHHHLGHYESHEGHVV 509

Query: 68  F-LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
             L  TH +V  D G Y C   NS G    + A ++V   R   R        A  D  V
Sbjct: 510 SQLNVTHTQVQ-DGGQYRCTCGNSAGVVHHQ-ARINVRG-RASVRAMKNLTAIAGRDAFV 566

Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
             C    G P  ++ W KN   L F+   R    + G L + + +Q DAG Y C      
Sbjct: 567 -HCRVI-GYPYYSIKWYKNSALLPFNHRQRA-FENNGTLKLSNVQQVDAGEYTCKVMVQP 623

Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQT-GSSVTFQCRV-GGDPLPDVLWRRSAGGGNM 244
              +S    +++ + PY+   P +    T G  V   C V  GD   D+ W++   G  +
Sbjct: 624 NKMDSQSVHVRVRVPPYI--QPFEFQRFTIGQRVFIPCVVMSGDRPLDITWQKD--GRPI 679

Query: 245 PLGRVKVLDD----GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
           P G    +D+     SLR++N+     G Y+C A N   AV     L V  PP   + P 
Sbjct: 680 PAGLGVTVDNIDFTSSLRINNLTPDHNGNYTCIARNEAAAVEHQSRLIVRVPPQFVVQPE 739

Query: 301 SVNVESGNVARFTCTATGRPEPTMFW 326
             +   G      C+A G P PT+ W
Sbjct: 740 DQDGIYGKTVTLNCSAEGYPPPTIVW 765



 Score = 97.1 bits (231), Expect = 3e-18
 Identities = 111/472 (23%), Positives = 178/472 (37%), Gaps = 42/472 (8%)

Query: 31  LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
           L C+A G P+P  RW K    +  D+ R      GL    A  G    D+G Y CE  NS
Sbjct: 287 LPCKASGYPAPKYRWLKDNSPLEPDS-RFRQTVTGLLIESAQPG----DSGTYVCEVWNS 341

Query: 91  YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
           YG A           L+    + P   + + G  V L C    GS E  + W +NG+ ++
Sbjct: 342 YGNAEVVGRLYVKQPLKAV--VSPRKVKGSVGSKVSLSC-SVSGSDEYELSWYRNGE-II 397

Query: 151 FDGDS-RMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
           + G+S R   ++  NL+++   ++D G YQC AR    + +  +  +     P +++   
Sbjct: 398 YPGNSVRFTGLNRENLIMEGMSKSDGGAYQCFARKGKMSAQDFVQVILEDGTPKILSSFS 457

Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGGGNMPLGRVKVLDD---GSLRLDNV 262
           + V      V   C V G P P   W           +  LG  +  +      L + + 
Sbjct: 458 EKVVNPNEPVFLVCNVKGTPPPRCSWSLDDDPVIKDSHHHLGHYESHEGHVVSQLNVTHT 517

Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEP 322
            + D G+Y C   NS G V     + V    S+    N   + +G  A   C   G P  
Sbjct: 518 QVQDGGQYRCTCGNSAGVVHHQARINVRGRASVRAMKNLTAI-AGRDAFVHCRVIGYPYY 576

Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV---NYAG 379
           ++ W      + + P   R +      F+    L +++  + D+     C  +   N   
Sbjct: 577 SIKWY---KNSALLPFNHRQR-----AFENNGTLKLSNVQQVDA-GEYTCKVMVQPNKMD 627

Query: 380 SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGEAL 438
           S  V  ++       R PP I      Q   I      PC  +    P+ I W  +G  +
Sbjct: 628 SQSVHVRV-------RVPPYI-QPFEFQRFTIGQRVFIPCVVMSGDRPLDITWQKDGRPI 679

Query: 439 IQNHRRNVTN---DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
                  V N     +L + +L    +G YTC+A +          L+V  P
Sbjct: 680 PAGLGVTVDNIDFTSSLRINNLTPDHNGNYTCIARNEAAAVEHQSRLIVRVP 731



 Score = 95.1 bits (226), Expect = 1e-17
 Identities = 132/535 (24%), Positives = 207/535 (38%), Gaps = 46/535 (8%)

Query: 83  YWCEATNSYGTARSRNATLHVAVLREEFRLEP------ESKQSAQGDTVVLECLPPRGSP 136
           Y C   + Y T  +R +     ++ +    EP      E ++      V L C    G P
Sbjct: 238 YRCTTRHRY-TGETRQSNSARLIVSDPTNAEPAILDGFERREVMISHRVELPC-KASGYP 295

Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
            P   W K+   L  + DSR      G L+I+ A+  D+G Y C   N+ G  E  +  L
Sbjct: 296 APKYRWLKDNSPL--EPDSRFRQTVTG-LLIESAQPGDSGTYVCEVWNSYGNAE-VVGRL 351

Query: 197 KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDD 254
            +      +  P  V    GS V+  C V G    ++ W R+ G    P   V+   L+ 
Sbjct: 352 YVKQPLKAVVSPRKVKGSVGSKVSLSCSVSGSDEYELSWYRN-GEIIYPGNSVRFTGLNR 410

Query: 255 GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---DPPSINLSPNSVNVESGNVAR 311
            +L ++ +  +D G Y C A    G +SA  ++ V      P I LS  S  V + N   
Sbjct: 411 ENLIMEGMSKSDGGAYQCFARK--GKMSAQDFVQVILEDGTPKI-LSSFSEKVVNPNEPV 467

Query: 312 F-TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG-----VTVLTINDTDKND 365
           F  C   G P P   WS++ +  I      +D +H    ++      V+ L +  T   D
Sbjct: 468 FLVCNVKGTPPPRCSWSLDDDPVI------KDSHHHLGHYESHEGHVVSQLNVTHTQVQD 521

Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
                 C+  N AG    + ++ V                N T      A   C  I  P
Sbjct: 522 G-GQYRCTCGNSAGVVHHQARINVRGRAS------VRAMKNLTAIAGRDAFVHCRVIGYP 574

Query: 426 EPIIAWYFEGEALIQNHR-RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
              I WY     L  NHR R   N+GTL L ++ + D+G YTC    +  K + S ++ V
Sbjct: 575 YYSIKWYKNSALLPFNHRQRAFENNGTLKLSNVQQVDAGEYTCKVMVQPNK-MDSQSVHV 633

Query: 485 DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE--V 542
              + P I  F      ++      P      D  + ++W ++ +   +  LG  V+   
Sbjct: 634 RVRVPPYIQPFEFQRF-TIGQRVFIPCVVMSGDRPLDITWQKDGRPIPAG-LGVTVDNID 691

Query: 543 FSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSG 597
           F+      N TP ++  +  IAR           LI  +   F+V+ E+  G+ G
Sbjct: 692 FTSSLRINNLTPDHNGNYTCIARNEAAAVEHQSRLIVRVPPQFVVQPEDQDGIYG 746



 Score = 77.0 bits (181), Expect = 3e-12
 Identities = 57/222 (25%), Positives = 93/222 (41%), Gaps = 7/222 (3%)

Query: 20  DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
           ++T    + A ++CR  G P  +I+WYK   L+  +  +      G   L         D
Sbjct: 555 NLTAIAGRDAFVHCRVIGYPYYSIKWYKNSALLPFNHRQRAFENNGTLKLSNVQ---QVD 611

Query: 80  AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
           AG Y C+         S++  +HV V    +    E ++   G  V + C+   G    +
Sbjct: 612 AGEYTCKVMVQPNKMDSQS--VHVRVRVPPYIQPFEFQRFTIGQRVFIPCVVMSGDRPLD 669

Query: 140 VYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
           + W+K+G+ +       +  +D   +L I +      G Y CIARN A   E   + L +
Sbjct: 670 ITWQKDGRPIPAGLGVTVDNIDFTSSLRINNLTPDHNGNYTCIARNEAAAVEHQ-SRLIV 728

Query: 199 HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
            + P  +  PED     G +VT  C   G P P ++W  S G
Sbjct: 729 RVPPQFVVQPEDQDGIYGKTVTLNCSAEGYPPPTIVWEHSKG 770



 Score = 63.3 bits (147), Expect = 4e-08
 Identities = 94/415 (22%), Positives = 154/415 (37%), Gaps = 37/415 (8%)

Query: 30  TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
           +L+C   GS    + WY+ G ++      S+   G         G   SD G Y C A  
Sbjct: 375 SLSCSVSGSDEYELSWYRNGEIIYPG--NSVRFTGLNRENLIMEGMSKSDGGAYQCFARK 432

Query: 90  SYGTARSRNATLHVAVLREEFR---LEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146
              +A+       V V+ E+     L   S++    +  V      +G+P P   W  + 
Sbjct: 433 GKMSAQD-----FVQVILEDGTPKILSSFSEKVVNPNEPVFLVCNVKGTPPPRCSWSLDD 487

Query: 147 QTLLFDGDSRMHLVDG--GNLVIQ----DARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
             ++ D    +   +   G++V Q      +  D G+Y+C   N+AG      A + +  
Sbjct: 488 DPVIKDSHHHLGHYESHEGHVVSQLNVTHTQVQDGGQYRCTCGNSAGVVHHQ-ARINVRG 546

Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLD-DGSLR 258
           +   +   +++ A  G      CRV G P   + W +++    +P   R +  + +G+L+
Sbjct: 547 RA-SVRAMKNLTAIAGRDAFVHCRVIGYPYYSIKWYKNS--ALLPFNHRQRAFENNGTLK 603

Query: 259 LDNVILADEGEYSCEAENSVGAV-SASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
           L NV   D GEY+C+       + S S ++ V  PP I           G      C   
Sbjct: 604 LSNVQQVDAGEYTCKVMVQPNKMDSQSVHVRVRVPPYIQ-PFEFQRFTIGQRVFIPCVVM 662

Query: 318 GRPEP-TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
               P  + W  +G       G++ D        D  + L IN+    D      C A N
Sbjct: 663 SGDRPLDITWQKDGRPIPAGLGVTVDN------IDFTSSLRINNLTP-DHNGNYTCIARN 715

Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431
            A +   + +L V     R PP     P +Q           C+A   P P I W
Sbjct: 716 EAAAVEHQSRLIV-----RVPPQFVVQPEDQDGIYGKTVTLNCSAEGYPPPTIVW 765



 Score = 62.9 bits (146), Expect = 5e-08
 Identities = 79/336 (23%), Positives = 124/336 (36%), Gaps = 33/336 (9%)

Query: 156 RMHLVDGGNLVIQDARQTDA-GRYQCIARN--AAGTRESAIATLKI----HIKPYLITGP 208
           R  +   G L I D    D    Y+C  R+     TR+S  A L +    + +P ++ G 
Sbjct: 215 RYLITSAGALYILDVLPEDGLNNYRCTTRHRYTGETRQSNSARLIVSDPTNAEPAILDGF 274

Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268
           E         V   C+  G P P   W +       P  R +    G L +++    D G
Sbjct: 275 ERREVMISHRVELPCKASGYPAPKYRWLKD-NSPLEPDSRFRQTVTGLL-IESAQPGDSG 332

Query: 269 EYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328
            Y CE  NS G     G L V  P    +SP  V    G+    +C+ +G  E  + W  
Sbjct: 333 TYVCEVWNSYGNAEVVGRLYVKQPLKAVVSPRKVKGSVGSKVSLSCSVSGSDEYELSWYR 392

Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVT--VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
            G   II+PG S         F G+    L +    K+D      C A    G    +  
Sbjct: 393 NGE--IIYPGNS-------VRFTGLNRENLIMEGMSKSDG-GAYQCFA--RKGKMSAQDF 440

Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNV 446
           + V  +D  P   I +  S + +         C    TP P  +W  + + +I++   ++
Sbjct: 441 VQVILEDGTPK--ILSSFSEKVVNPNEPVFLVCNVKGTPPPRCSWSLDDDPVIKDSHHHL 498

Query: 447 ----TNDGTLV----LKDLDKSDSGTYTCVASSRHG 474
               +++G +V    +      D G Y C   +  G
Sbjct: 499 GHYESHEGHVVSQLNVTHTQVQDGGQYRCTCGNSAG 534



 Score = 61.7 bits (143), Expect = 1e-07
 Identities = 134/601 (22%), Positives = 229/601 (38%), Gaps = 55/601 (9%)

Query: 239  AGGGNMPLGRVKVLDDGSLRLDNVILAD-EGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
            AGG      R  +L +GSL + +V+  D E  Y C+  N VGA +   ++      S+ L
Sbjct: 810  AGGMTASAARALLLSNGSLLIKHVLEDDSESMYLCKVSNDVGADAQQVHVAHRQELSM-L 868

Query: 298  SPNSVNVESGNVARFTCTATGRPEPTMF-WSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
               +      +V R  C     P   +  W       +  P  +R            T L
Sbjct: 869  GGGARVGPLADVLRSCCWWRRNPSYCLRRWLTPATGYLRLPEANRLTGGCLP-----TSL 923

Query: 357  TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416
             I  T + DS     C A+N  G      +LTV    D PP +      ++T+ ++    
Sbjct: 924  QIMPTVREDS-GFFSCHAINSFGEDRGIIQLTVQEPPD-PPEVEIREVKDRTIALRWTMG 981

Query: 417  FPCTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRH 473
            F   +  T   I         L     ++V+   N  T++  DL  S +     VA +  
Sbjct: 982  FDGNSPITGYDIECKNKSASWLSAQVTKDVSPQLNQATII--DLHPSSTYNIRMVAKNVI 1039

Query: 474  GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSS 533
            G              NP+       D ++  GPP        +  S+ +SW    +   +
Sbjct: 1040 GNS------------NPSNELTITTDEAAPDGPPLDVTLEPTSPQSIKVSWKVRPRPQGT 1087

Query: 534  SILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSH 593
             + G +  +     L      ++ +  V+   R +Q  Y  +   PG ++ F + + ++ 
Sbjct: 1088 CLKGRRALILP---LLLQPPLKHLQNGVI---RGYQVGY--REYSPGGSHQFTIVSVDTP 1139

Query: 594  G-------LSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDS 646
            G       L G    +    V   +N    G     + E   +   D+++ + ++  + S
Sbjct: 1140 GDTTESLTLDGLKKFTQYSVVVQAANRAGTGPWSPKTLEDVPSRTPDNVLAVAKSPEVIS 1199

Query: 647  KT-IKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVS-GFEITSLRKYTKYE 704
             + + L  E+LN   L    IY+  L     + E+  I +   V    E+  L KYT Y 
Sbjct: 1200 VSWMPLPREVLNVNLLGYRVIYWANLP----DGELGEIRNVTAVQPSLELDGLEKYTNYR 1255

Query: 705  FFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGII 764
              ++ F    +G  S     +T +DVP GPP  ++    +++ V + W PP L+L NGII
Sbjct: 1256 IQVLAFTSAGDGVRSEQIYVRTKEDVP-GPPAGVKAAASSSSAVFVSWLPP-LKL-NGII 1312

Query: 765  TGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQK 824
              Y +  + L  P   S    +   H      + NL     Y++ + A T  G G  S+K
Sbjct: 1313 RKYIIFCSDLH-PMVMSEFEASPDAH---FYRIPNLAGNRQYTIWVVAVTAAGHGNNSEK 1368

Query: 825  V 825
            +
Sbjct: 1369 I 1369



 Score = 61.3 bits (142), Expect = 2e-07
 Identities = 71/247 (28%), Positives = 103/247 (41%), Gaps = 38/247 (15%)

Query: 369  TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT-NGPSNQTLPIKSMAVFPCTAICTPEP 427
            TI   AV  AG      K+TV      P  I+T NG    T P     V PC A+  P P
Sbjct: 1351 TIWVVAVTAAGHGNNSEKITVEPLAKAPARILTFNG--TVTTPWMKDIVLPCKAVGDPPP 1408

Query: 428  IIAWYFEGEA------LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
             + W  +G A      ++ + RR V  +G+  ++ +   DSG Y+CVA +      W G 
Sbjct: 1409 TVKW-IKGSANGTPTNVLVDGRRTVHANGSFFIRTVKAEDSGNYSCVAGN-----TWGG- 1461

Query: 482  LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541
                  I  N+       V   P  P   +T   T TS+TLSW   +  G SSI GY ++
Sbjct: 1462 ----DEITLNL------QVQVPPDQPRLTVT-KTTTTSITLSWIPGDN-GGSSIRGYILQ 1509

Query: 542  VFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPV 601
             +S +         NS  W        +  Y +++L  G  Y F +  +N  G    S +
Sbjct: 1510 -YSED---------NSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNVVGPGRISEI 1559

Query: 602  SDSVTVG 608
             ++ T G
Sbjct: 1560 IEAKTHG 1566



 Score = 50.4 bits (115), Expect = 3e-04
 Identities = 40/150 (26%), Positives = 70/150 (46%), Gaps = 10/150 (6%)

Query: 13  YIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTH--RSILPAGGL--- 66
           Y +   L +V  A     ++ C AGG+   ++RWY      + D    R + P G L   
Sbjct: 19  YFVNASLQEVVFASTTGTSVPCPAGGAAPASLRWYLATGEEIYDVPGIRHVHPNGTLQIF 78

Query: 67  FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
            FL +++ ++  D   Y+C A N  G  RS++  +  AV RE + +    +++ +G   V
Sbjct: 79  NFLPSSYSKLIHD-NTYYCTAENPSGKIRSQDVHIK-AVSREPYTVRVADQKAMRGSVAV 136

Query: 127 LECLPPRGSPE--PNVYWKKNGQTLLFDGD 154
            +C+ P         V W+K+  +L  +GD
Sbjct: 137 FKCIIPASVEAYIAVVSWEKDTVSLSSEGD 166



 Score = 48.8 bits (111), Expect = 9e-04
 Identities = 35/133 (26%), Positives = 61/133 (45%), Gaps = 6/133 (4%)

Query: 694  ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
            +  L+K+T+Y   +    +   G  S     +TL+DVP   P N+     +   + + W 
Sbjct: 1148 LDGLKKFTQYSVVVQAANRAGTGPWS----PKTLEDVPSRTPDNVLAVAKSPEVISVSWM 1203

Query: 754  PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAE 813
            P   ++ N  + GY V+  W ++P  +     N T  Q  SL +  L    +Y +Q+ A 
Sbjct: 1204 PLPREVLNVNLLGYRVIY-WANLPDGELGEIRNVTAVQ-PSLELDGLEKYTNYRIQVLAF 1261

Query: 814  TIIGLGPFSQKVY 826
            T  G G  S+++Y
Sbjct: 1262 TSAGDGVRSEQIY 1274



 Score = 45.6 bits (103), Expect = 0.008
 Identities = 36/135 (26%), Positives = 51/135 (37%), Gaps = 3/135 (2%)

Query: 356 LTINDTDKNDSRNTIVCSAVN-YAGSSFVRGKLT-VTSDDDRPPPIITNGPSNQTLPIKS 413
           L I D    D  N   C+  + Y G +        + SD     P I +G   + + I  
Sbjct: 224 LYILDVLPEDGLNNYRCTTRHRYTGETRQSNSARLIVSDPTNAEPAILDGFERREVMISH 283

Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
               PC A   P P   W  +   L  + R   T  G L+++     DSGTY C   + +
Sbjct: 284 RVELPCKASGYPAPKYRWLKDNSPLEPDSRFRQTVTG-LLIESAQPGDSGTYVCEVWNSY 342

Query: 474 GKYVWSGALLVDSPI 488
           G     G L V  P+
Sbjct: 343 GNAEVVGRLYVKQPL 357



 Score = 44.8 bits (101), Expect = 0.015
 Identities = 36/141 (25%), Positives = 58/141 (41%), Gaps = 25/141 (17%)

Query: 718  PSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS-----------------------P 754
            PSN     T +  PDGPP+++ +   +  ++ + W                        P
Sbjct: 1044 PSNELTITTDEAAPDGPPLDVTLEPTSPQSIKVSWKVRPRPQGTCLKGRRALILPLLLQP 1103

Query: 755  PELQLQNGIITGYNVVVNWLDVPANK--SMVAINTTVHQATSLIMTNLTSGVSYSVQIAA 812
            P   LQNG+I GY V         +   ++V+++T      SL +  L     YSV + A
Sbjct: 1104 PLKHLQNGVIRGYQVGYREYSPGGSHQFTIVSVDTPGDTTESLTLDGLKKFTQYSVVVQA 1163

Query: 813  ETIIGLGPFSQKVYFNIDSRS 833
                G GP+S K   ++ SR+
Sbjct: 1164 ANRAGTGPWSPKTLEDVPSRT 1184



 Score = 41.5 bits (93), Expect = 0.14
 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 4/79 (5%)

Query: 219  VTFQCRVGGDPLPDVLWRRSAGGGN----MPLGRVKVLDDGSLRLDNVILADEGEYSCEA 274
            +   C+  GDP P V W + +  G     +  GR  V  +GS  +  V   D G YSC A
Sbjct: 1396 IVLPCKAVGDPPPTVKWIKGSANGTPTNVLVDGRRTVHANGSFFIRTVKAEDSGNYSCVA 1455

Query: 275  ENSVGAVSASGYLTVYDPP 293
             N+ G    +  L V  PP
Sbjct: 1456 GNTWGGDEITLNLQVQVPP 1474



 Score = 40.7 bits (91), Expect = 0.24
 Identities = 26/77 (33%), Positives = 37/77 (48%), Gaps = 9/77 (11%)

Query: 21   VTVARHQPATLNCRAGGSPSPAIRWYKGG-----VLVVSDTHRSILPAGGLFFLRATHGR 75
            VT    +   L C+A G P P ++W KG        V+ D  R++  A G FF+R     
Sbjct: 1388 VTTPWMKDIVLPCKAVGDPPPTVKWIKGSANGTPTNVLVDGRRTV-HANGSFFIRTVKA- 1445

Query: 76   VHSDAGVYWCEATNSYG 92
               D+G Y C A N++G
Sbjct: 1446 --EDSGNYSCVAGNTWG 1460



 Score = 39.1 bits (87), Expect = 0.72
 Identities = 27/83 (32%), Positives = 39/83 (46%), Gaps = 9/83 (10%)

Query: 125  VVLECLPPRGSPEPNVYWKK---NGQ--TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179
            +VL C    G P P V W K   NG    +L DG   +H    G+  I+  +  D+G Y 
Sbjct: 1396 IVLPCKAV-GDPPPTVKWIKGSANGTPTNVLVDGRRTVHA--NGSFFIRTVKAEDSGNYS 1452

Query: 180  CIARNAAGTRESAIATLKIHIKP 202
            C+A N  G  E  +  L++ + P
Sbjct: 1453 CVAGNTWGGDEITL-NLQVQVPP 1474


>UniRef50_Q4RHM4 Cluster: Chromosome 19 SCAF15045, whole genome
           shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
           Chromosome 19 SCAF15045, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 1193

 Score = 98.7 bits (235), Expect = 8e-19
 Identities = 81/242 (33%), Positives = 113/242 (46%), Gaps = 19/242 (7%)

Query: 78  SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ--SAQGDTVVLECLPPRGS 135
           +D+G+Y C A N +G  +  NA L V      F L P  KQ   A+   VV+EC  PR +
Sbjct: 435 ADSGMYQCVAENYWG-IKYANAELRVIAFAPTFELNPVKKQLLGARDRRVVIEC-KPRAA 492

Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195
           P P   W K G+ LLF+ +SR+ ++  G+L I  A + D G Y C+A N  G R ++   
Sbjct: 493 PRPQFTWTK-GKELLFN-NSRLSILYDGSLEILSATKDDEGVYTCLAENGRG-RANSSGY 549

Query: 196 LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV--LW----RRSAGGGNMPLGRV 249
           L I     +   PED  A+ G  V  +C    DP  D+  +W    R             
Sbjct: 550 LTITEATGITVAPEDSEAKVGDEVVLRCAASFDPTLDITFIWAIDFRVIDFDSEWQHYER 609

Query: 250 KVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES- 306
              DDGS  L++ NV +  EG Y+C A+  V + +A   L V   P     P  + VE  
Sbjct: 610 LWRDDGSGDLKIKNVQIWHEGRYTCTAQTVVDSDTAYADLKVVGVPG---PPGVIRVEEI 666

Query: 307 GN 308
           GN
Sbjct: 667 GN 668



 Score = 75.4 bits (177), Expect = 9e-12
 Identities = 47/173 (27%), Positives = 76/173 (43%), Gaps = 9/173 (5%)

Query: 163 GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP--EDVVAQTGSSVT 220
           G L        D+G YQC+A N  G + +      I   P     P  + ++      V 
Sbjct: 425 GELQFSSLTFADSGMYQCVAENYWGIKYANAELRVIAFAPTFELNPVKKQLLGARDRRVV 484

Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMPLG--RVKVLDDGSLRLDNVILADEGEYSCEAENSV 278
            +C+    P P   W +   G  +     R+ +L DGSL + +    DEG Y+C AEN  
Sbjct: 485 IECKPRAAPRPQFTWTK---GKELLFNNSRLSILYDGSLEILSATKDDEGVYTCLAENGR 541

Query: 279 GAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EPTMFWSVE 329
           G  ++SGYLT+ +   I ++P     + G+     C A+  P  + T  W+++
Sbjct: 542 GRANSSGYLTITEATGITVAPEDSEAKVGDEVVLRCAASFDPTLDITFIWAID 594



 Score = 65.3 bits (152), Expect = 1e-08
 Identities = 55/182 (30%), Positives = 83/182 (45%), Gaps = 15/182 (8%)

Query: 24  ARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVY 83
           AR +   + C+   +P P   W KG  L+ +++  SIL  G L  L AT      D GVY
Sbjct: 478 ARDRRVVIECKPRAAPRPQFTWTKGKELLFNNSRLSILYDGSLEILSAT----KDDEGVY 533

Query: 84  WCEATNSYGTARSRN-ATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP-RGSPEPNVY 141
            C A N  G A S    T+  A       + PE  ++  GD VVL C      + +    
Sbjct: 534 TCLAENGRGRANSSGYLTITEAT---GITVAPEDSEAKVGDEVVLRCAASFDPTLDITFI 590

Query: 142 WKKNGQTLLFDGD----SRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
           W  + + + FD +     R+   DG G+L I++ +    GRY C A+    + ++A A L
Sbjct: 591 WAIDFRVIDFDSEWQHYERLWRDDGSGDLKIKNVQIWHEGRYTCTAQTVVDS-DTAYADL 649

Query: 197 KI 198
           K+
Sbjct: 650 KV 651



 Score = 52.4 bits (120), Expect = 7e-05
 Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 4/114 (3%)

Query: 372 CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM-AVFPCTAICTPEPIIA 430
           C A NY G  +   +L V +     P    N    Q L  +    V  C     P P   
Sbjct: 442 CVAENYWGIKYANAELRVIAF---APTFELNPVKKQLLGARDRRVVIECKPRAAPRPQFT 498

Query: 431 WYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
           W    E L  N R ++  DG+L +    K D G YTC+A +  G+   SG L +
Sbjct: 499 WTKGKELLFNNSRLSILYDGSLEILSATKDDEGVYTCLAENGRGRANSSGYLTI 552



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 25/68 (36%), Positives = 34/68 (50%), Gaps = 1/68 (1%)

Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTD-AGRYQCIARNAAGTR 189
           P R S  P  + + N +  L +     + + GGNLVI   ++   AG Y C+ARN  GT 
Sbjct: 32  PGRLSSLPGRWRRDNWEIKLMEQPDEHYSLVGGNLVINSPKKRKHAGTYICVARNIYGTV 91

Query: 190 ESAIATLK 197
            S  A LK
Sbjct: 92  ISKEARLK 99


>UniRef50_A7RGM1 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 551

 Score = 98.7 bits (235), Expect = 8e-19
 Identities = 121/485 (24%), Positives = 195/485 (40%), Gaps = 63/485 (12%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P  I+    V V   Q AT  C   G P P+I W+K G+ +  +   +    G L  L  
Sbjct: 1   PQFIDLMQPVEVTEGQTATFECTVKGYPRPSIEWFKNGLPLKENERIASTYEGALSSLTI 60

Query: 72  THGRVHSDAGVYWCEATNSYGTARSRNATL------HV---AVLREEFRLEPESKQSAQG 122
               +  D G Y C A NS+G A      L      H      + + F   P ++ + +G
Sbjct: 61  NQCTI-DDEGNYKCVARNSFGKASCATELLTNLNGTHTHPPHFIDKHFETAP-AEVTEEG 118

Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCI 181
           D V LE +   G P+P+V W K+ + ++      +    D   LVI    Q D G+Y+ I
Sbjct: 119 D-VRLE-VRVGGHPKPSVQWLKDDEVIISSPHFMVSSHADVHTLVINSPNQDDIGQYKVI 176

Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
           A N  G    A  T  ++++                         G P P V W +    
Sbjct: 177 ASNHRG---MASRTFDVNVE-------------------------GKPKPSVEWLKD-DR 207

Query: 242 GNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
             +    +K+ ++    SL +     +DEG Y+ +  N VG+ + +  + V D  + +  
Sbjct: 208 PVLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVGSGTRTFDVKVEDTTTNDSF 267

Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
               + E GNV R +   TG+P P + W+ +         +  D        D +  LTI
Sbjct: 268 VPFESTEEGNV-RLSVKITGKPVPEVSWTKDEKPVHKIQNIRLDHQ------DDIYTLTI 320

Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD--DDRPPPIITNGP--SNQTLPIKSM 414
            +   NDS  +  C+  N AG S     + +  +   ++  P    G     + LP+ + 
Sbjct: 321 REATPNDS-GSYKCTLTNDAGKSTRTFSVEIEGETKPEKGKPTEREGKPLEEEELPVSAE 379

Query: 415 AVFPCTAICT--PEPIIAWYFEGEALIQNHRRNVT-NDGT--LVLKDLDKSDSGTYTCVA 469
                TA  T  P+P + W+ +   +  +    +T  DGT  LV+K+  K D GTYT   
Sbjct: 380 TEVEMTAQVTGKPQPSVEWFKDDVPVSPDEHITITEEDGTYSLVIKEPTKKDEGTYTVEV 439

Query: 470 SSRHG 474
           S+  G
Sbjct: 440 SNEAG 444



 Score = 72.9 bits (171), Expect = 5e-11
 Identities = 94/378 (24%), Positives = 150/378 (39%), Gaps = 39/378 (10%)

Query: 30  TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
           T +    G P P++ W K    V+SD+H  +     ++ L        SD G+Y  + TN
Sbjct: 187 TFDVNVEGKPKPSVEWLKDDRPVLSDSHIKMTEEDDIYSLTIREP-TKSDEGMYTVKITN 245

Query: 90  SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
             G+  +R   + V          P   +S +   V L  +   G P P V W K+ + +
Sbjct: 246 DVGSG-TRTFDVKVEDTTTNDSFVPF--ESTEEGNVRLS-VKITGKPVPEVSWTKDEKPV 301

Query: 150 LFDGDSRM-HLVDGGNLVIQDARQTDAGRYQCIARNAAG--TRESAIA----TLKIHIKP 202
               + R+ H  D   L I++A   D+G Y+C   N AG  TR  ++     T     KP
Sbjct: 302 HKIQNIRLDHQDDIYTLTIREATPNDSGSYKCTLTNDAGKSTRTFSVEIEGETKPEKGKP 361

Query: 203 YLITGP----EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG--S 256
               G     E++     + V    +V G P P V W +     +         +DG  S
Sbjct: 362 TEREGKPLEEEELPVSAETEVEMTAQVTGKPQPSVEWFKDDVPVSPDEHITITEEDGTYS 421

Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP----PSINLSPNSV---------N 303
           L +      DEG Y+ E  N  G    +  ++V D     P   + P  +         +
Sbjct: 422 LVIKEPTKKDEGTYTVEVSNEAGLGRRTFDVSVDDTRKTIPKDAVKPKFIEDGSFVPFQS 481

Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
            + G+V R T   TG+PEP + W+ +G      P +  D  H    +    +LTI +   
Sbjct: 482 TDEGDV-RLTVKVTGKPEPEVTWTKDGKPVDKLPNVELD--HQEDRY----ILTIREASP 534

Query: 364 NDSRNTIVCSAVNYAGSS 381
           +DS  +  C+  +  G S
Sbjct: 535 DDS-GSYRCTLTSDVGKS 551



 Score = 62.5 bits (145), Expect = 7e-08
 Identities = 94/388 (24%), Positives = 159/388 (40%), Gaps = 63/388 (16%)

Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRY 178
           +G T   EC   +G P P++ W KNG  L  + +      +G   +L I      D G Y
Sbjct: 14  EGQTATFECTV-KGYPRPSIEWFKNGLPLK-ENERIASTYEGALSSLTINQCTIDDEGNY 71

Query: 179 QCIARNAAGTRESAIATLK----IHIKP------YLITGPEDVVAQTGSSVTFQCRVGGD 228
           +C+ARN+ G    A   L      H  P      +  T P +V  +    V  + RVGG 
Sbjct: 72  KCVARNSFGKASCATELLTNLNGTHTHPPHFIDKHFETAPAEVTEE--GDVRLEVRVGGH 129

Query: 229 PLPDVLWRRSAGGG-NMPLGRVKV-LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY 286
           P P V W +      + P   V    D  +L +++    D G+Y   A N  G  S +  
Sbjct: 130 PKPSVQWLKDDEVIISSPHFMVSSHADVHTLVINSPNQDDIGQYKVIASNHRGMASRT-- 187

Query: 287 LTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHA 346
              +D          VNVE            G+P+P++ W ++ +R ++      D +  
Sbjct: 188 ---FD----------VNVE------------GKPKPSVEW-LKDDRPVL-----SDSHIK 216

Query: 347 TAVFDGVTVLTINDTDKNDS-RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPS 405
               D +  LTI +  K+D    T+  +    +G+     K+  T+ +D   P  +    
Sbjct: 217 MTEEDDIYSLTIREPTKSDEGMYTVKITNDVGSGTRTFDVKVEDTTTNDSFVPFESTEEG 276

Query: 406 NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL--IQNHRRNVTND-GTLVLKDLDKSDS 462
           N  L +K            P P ++W  + + +  IQN R +  +D  TL +++   +DS
Sbjct: 277 NVRLSVKITG--------KPVPEVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATPNDS 328

Query: 463 GTYTCVASSRHGKYVWSGALLVDSPINP 490
           G+Y C  ++  GK   + ++ ++    P
Sbjct: 329 GSYKCTLTNDAGKSTRTFSVEIEGETKP 356



 Score = 51.2 bits (117), Expect = 2e-04
 Identities = 45/181 (24%), Positives = 73/181 (40%), Gaps = 17/181 (9%)

Query: 20  DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
           ++ V+      +  +  G P P++ W+K  V V  D H +I    G + L         D
Sbjct: 373 ELPVSAETEVEMTAQVTGKPQPSVEWFKDDVPVSPDEHITITEEDGTYSL-VIKEPTKKD 431

Query: 80  AGVYWCEATNSYGTAR--------SRNATLHVAVLREEFRLEPES----KQSAQGDTVVL 127
            G Y  E +N  G  R            T+    ++ +F +E  S    + + +GD  V 
Sbjct: 432 EGTYTVEVSNEAGLGRRTFDVSVDDTRKTIPKDAVKPKF-IEDGSFVPFQSTDEGD--VR 488

Query: 128 ECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
             +   G PEP V W K+G+ +         H  D   L I++A   D+G Y+C   +  
Sbjct: 489 LTVKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDV 548

Query: 187 G 187
           G
Sbjct: 549 G 549



 Score = 43.2 bits (97), Expect = 0.044
 Identities = 46/203 (22%), Positives = 80/203 (39%), Gaps = 16/203 (7%)

Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG-VTVLTIND 360
           V V  G  A F CT  G P P++ W   G      P    ++  +T  ++G ++ LTIN 
Sbjct: 10  VEVTEGQTATFECTVKGYPRPSIEWFKNG-----LPLKENERIAST--YEGALSSLTINQ 62

Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKL--TVTSDDDRPPPIITNGPSNQTLPI--KSMAV 416
              +D  N   C A N  G +    +L   +      PP  I          +  +    
Sbjct: 63  CTIDDEGN-YKCVARNSFGKASCATELLTNLNGTHTHPPHFIDKHFETAPAEVTEEGDVR 121

Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRH 473
                   P+P + W  + E +I +    V++     TLV+   ++ D G Y  +AS+  
Sbjct: 122 LEVRVGGHPKPSVQWLKDDEVIISSPHFMVSSHADVHTLVINSPNQDDIGQYKVIASNHR 181

Query: 474 GKYVWSGALLVDSPINPNIHFFR 496
           G    +  + V+    P++ + +
Sbjct: 182 GMASRTFDVNVEGKPKPSVEWLK 204


>UniRef50_Q4RVM1 Cluster: Chromosome 9 SCAF14991, whole genome
           shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 9
           SCAF14991, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 1197

 Score = 97.9 bits (233), Expect = 1e-18
 Identities = 84/321 (26%), Positives = 133/321 (41%), Gaps = 31/321 (9%)

Query: 6   VTSGEAP-YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
           +  G  P ++   P D  +       + C   G PS  I W K G L + D   +     
Sbjct: 251 MVEGAPPEWLTGPPQDQLLVIGSDVHIKCSVSGKPSSDIIWRKNGELFIDDPENNRRVLD 310

Query: 65  GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEF--------RLEPES 116
               L   H     D  VY C+A+N +G      A +++ V+ E          R+    
Sbjct: 311 DTVVL---HNAGPEDTAVYQCDASNGHGGLL---ANINIMVMSESQGSLLDMTPRILTSD 364

Query: 117 KQS---AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT 173
            Q     QG  V++ C     SP P + W +        G+ R   +  G+L I  A + 
Sbjct: 365 SQEYPVVQGVDVIMNC-SAFSSPLPTISWFRGANQEAVKGE-RFFTLQNGSLQIIGAEKN 422

Query: 174 DAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP-LPD 232
           D+G+Y C+A N  G + +  A L +     +++GP D    +G++    C+   D  L D
Sbjct: 423 DSGKYVCVALNTEG-KAAVTAVLDVKDPTRIVSGPRDAEVMSGATAQLICQAEYDKSLQD 481

Query: 233 ---VLWRRSAGGGNMPLGRVK----VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASG 285
              ++WR+   G ++PL   +     + D  LR+ NV L D G Y C A  S+  ++A+ 
Sbjct: 482 SFVLVWRKD--GDDIPLSVEENSRYAVADSMLRIMNVALNDSGTYMCIARTSLDEMNATA 539

Query: 286 YLTVYDPPSINLSPNSVNVES 306
            LTV D P   L      + S
Sbjct: 540 LLTVLDVPDAPLKVEISEIRS 560



 Score = 95.5 bits (227), Expect = 8e-18
 Identities = 100/389 (25%), Positives = 159/389 (40%), Gaps = 40/389 (10%)

Query: 162 GGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG-PEDVVAQTGSSVT 220
           G  L++ +  ++D G+Y C A+N+AG        +     P  +TG P+D +   GS V 
Sbjct: 217 GRLLILSEVEESDGGQYMCKAKNSAGEAVHYFNVMVEGAPPEWLTGPPQDQLLVIGSDVH 276

Query: 221 FQCRVGGDPLPDVLWRRSAG-GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279
            +C V G P  D++WR++     + P    +VLDD ++ L N    D   Y C+A N  G
Sbjct: 277 IKCSVSGKPSSDIIWRKNGELFIDDPENNRRVLDD-TVVLHNAGPEDTAVYQCDASNGHG 335

Query: 280 AVSAS----------GYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVE 329
            + A+          G L    P  +        V  G      C+A   P PT+ W   
Sbjct: 336 GLLANINIMVMSESQGSLLDMTPRILTSDSQEYPVVQGVDVIMNCSAFSSPLPTISW--- 392

Query: 330 GNRTIIFPGMSRDKYHATAVFDGVT-VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT 388
                 F G +++       F      L I   +KNDS    VC A+N  G + V   L 
Sbjct: 393 ------FRGANQEAVKGERFFTLQNGSLQIIGAEKNDS-GKYVCVALNTEGKAAVTAVL- 444

Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA----ICTPEPIIAWYFEGEAL---IQN 441
               D + P  I +GP +  +   + A   C A          ++ W  +G+ +   ++ 
Sbjct: 445 ----DVKDPTRIVSGPRDAEVMSGATAQLICQAEYDKSLQDSFVLVWRKDGDDIPLSVEE 500

Query: 442 HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV----DSPINPNIHFFRA 497
           + R    D  L + ++  +DSGTY C+A +   +   +  L V    D+P+   I   R+
Sbjct: 501 NSRYAVADSMLRIMNVALNDSGTYMCIARTSLDEMNATALLTVLDVPDAPLKVEISEIRS 560

Query: 498 ADVSSLPGPPTKPITHNVTDTSVTLSWSQ 526
               SL   P      +VT+  V    SQ
Sbjct: 561 PRNISLSWVPGSDHNSSVTEFVVEFQESQ 589



 Score = 95.5 bits (227), Expect = 8e-18
 Identities = 88/332 (26%), Positives = 136/332 (40%), Gaps = 22/332 (6%)

Query: 78  SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
           SD G Y C+A NS G A      +      E     P+ +    G  V ++C    G P 
Sbjct: 228 SDGGQYMCKAKNSAGEAVHYFNVMVEGAPPEWLTGPPQDQLLVIGSDVHIKC-SVSGKPS 286

Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
            ++ W+KNG+  + D ++   ++D   +V+ +A   D   YQC A N  G   + I  + 
Sbjct: 287 SDIIWRKNGELFIDDPENNRRVLDD-TVVLHNAGPEDTAVYQCDASNGHGGLLANINIMV 345

Query: 198 --------IHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
                   + + P ++T   ++     G  V   C     PLP + W R A    +   R
Sbjct: 346 MSESQGSLLDMTPRILTSDSQEYPVVQGVDVIMNCSAFSSPLPTISWFRGANQEAVKGER 405

Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGN 308
              L +GSL++      D G+Y C A N+ G  + +  L V DP  I   P    V SG 
Sbjct: 406 FFTLQNGSLQIIGAEKNDSGKYVCVALNTEGKAAVTAVLDVKDPTRIVSGPRDAEVMSGA 465

Query: 309 VARFTCTA----TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
            A+  C A    + +    + W  +G+     P +S ++    AV D  ++L I +   N
Sbjct: 466 TAQLICQAEYDKSLQDSFVLVWRKDGDD---IP-LSVEENSRYAVAD--SMLRIMNVALN 519

Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP 396
           DS  T +C A            LTV    D P
Sbjct: 520 DS-GTYMCIARTSLDEMNATALLTVLDVPDAP 550



 Score = 62.1 bits (144), Expect = 9e-08
 Identities = 53/180 (29%), Positives = 73/180 (40%), Gaps = 12/180 (6%)

Query: 6   VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD--THRSILPA 63
           +TS     +I  P D TV       + C A G+P P  RW K G   V    T       
Sbjct: 7   ITSYSPGRVIALPFDKTVK------IECDARGNPPPQYRWTKDGEDFVPPRATTTKTQHT 60

Query: 64  GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
            G F L   + +     G Y C A N  GTA ++  TL V  + +  ++        +GD
Sbjct: 61  DGSFVLH--NKQFIQFQGTYRCYAFNKLGTAMTKEITLIVPTVPKFPKVGEPPIAVDEGD 118

Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAG-RYQCIA 182
            + L C PP G+    +YW      L+   D R+ +   GNL    A Q D+   Y C A
Sbjct: 119 PITLHCHPPEGAVPRQLYWMSLDLQLI-QQDERVSMGTDGNLYFSHALQNDSRLDYYCNA 177



 Score = 41.1 bits (92), Expect = 0.18
 Identities = 39/156 (25%), Positives = 62/156 (39%), Gaps = 6/156 (3%)

Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDG--DSRMHLVDGGNLVIQDARQTDAGRYQCI 181
           TV +EC   RG+P P   W K+G+  +      ++    DG  ++         G Y+C 
Sbjct: 23  TVKIEC-DARGNPPPQYRWTKDGEDFVPPRATTTKTQHTDGSFVLHNKQFIQFQGTYRCY 81

Query: 182 ARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
           A N  GT  +   TL +   P +   G   +    G  +T  C      +P  L+  S  
Sbjct: 82  AFNKLGTAMTKEITLIVPTVPKFPKVGEPPIAVDEGDPITLHCHPPEGAVPRQLYWMSLD 141

Query: 241 GGNMPLG-RVKVLDDGSLRLDNVILADEG-EYSCEA 274
              +    RV +  DG+L   + +  D   +Y C A
Sbjct: 142 LQLIQQDERVSMGTDGNLYFSHALQNDSRLDYYCNA 177


>UniRef50_Q9BWV1 Cluster: Brother of CDO precursor; n=27;
           Euteleostomi|Rep: Brother of CDO precursor - Homo
           sapiens (Human)
          Length = 1114

 Score = 97.9 bits (233), Expect = 1e-18
 Identities = 96/375 (25%), Positives = 148/375 (39%), Gaps = 28/375 (7%)

Query: 112 LEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR 171
           ++P S     G TV+L C+     P  NV W+ NG+ L    D+   L+  G LVI    
Sbjct: 40  VQPASTVQKPGGTVILGCVVE--PPRMNVTWRLNGKELNGSDDALGVLITHGTLVITALN 97

Query: 172 QTDAGRYQCIARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRV-GGDP 229
               GRYQC+AR  AG   S  AT+ + +++ + +     +    G++    C +    P
Sbjct: 98  NHTVGRYQCVARMPAGAVASVPATVTLANLQDFKLDVQHVIEVDEGNTAVIACHLPESHP 157

Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSV-GAVSASG--- 285
              V +           G   ++  G+L++ N    DEG Y C A N V   V  SG   
Sbjct: 158 KAQVRYSVKQEWLEASRGNYLIMPSGNLQIVNASQEDEGMYKCAAYNPVTQEVKTSGSSD 217

Query: 286 ----YLTVYDPPSINLSP--NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGM 339
                 +  +   I   P   ++ V  G      C A+G P P + W+ +G+        
Sbjct: 218 RLRVRRSTAEAARIIYPPEAQTIIVTKGQSLILECVASGIPPPRVTWAKDGS-------- 269

Query: 340 SRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPI 399
           S   Y+ T     ++ L I+ T + DS  T  C A N  G       + + +     PP 
Sbjct: 270 SVTGYNKTRFL--LSNLLIDTTSEEDS-GTYRCMADNGVGQP--GAAVILYNVQVFEPPE 324

Query: 400 ITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDK 459
           +T   S   +P    A   C     P P + W      LI + R  ++     VL  +  
Sbjct: 325 VTMELSQLVIPWGQSAKLTCEVRGNPPPSVLWLRNAVPLISSQRLRLSRRALRVL-SMGP 383

Query: 460 SDSGTYTCVASSRHG 474
            D G Y C+A +  G
Sbjct: 384 EDEGVYQCMAENEVG 398



 Score = 87.4 bits (207), Expect = 2e-15
 Identities = 82/280 (29%), Positives = 126/280 (45%), Gaps = 32/280 (11%)

Query: 21  VTVARHQPATLNCRAGGS-PSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS 78
           + V     A + C    S P   +R+  K   L  S  +  I+P+G L  + A+      
Sbjct: 138 IEVDEGNTAVIACHLPESHPKAQVRYSVKQEWLEASRGNYLIMPSGNLQIVNASQ----E 193

Query: 79  DAGVYWCEATN----------SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
           D G+Y C A N          S    R R +T   A  R  +  E ++    +G +++LE
Sbjct: 194 DEGMYKCAAYNPVTQEVKTSGSSDRLRVRRSTAEAA--RIIYPPEAQTIIVTKGQSLILE 251

Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
           C+   G P P V W K+G ++     +R  L    NL+I    + D+G Y+C+A N  G 
Sbjct: 252 CVAS-GIPPPRVTWAKDGSSVTGYNKTRFLL---SNLLIDTTSEEDSGTYRCMADNGVGQ 307

Query: 189 RESAIATLKIHI--KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
             +A+    + +   P +      +V   G S    C V G+P P VLW R+A    +PL
Sbjct: 308 PGAAVILYNVQVFEPPEVTMELSQLVIPWGQSAKLTCEVRGNPPPSVLWLRNA----VPL 363

Query: 247 ---GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSA 283
               R++ L   +LR+ ++   DEG Y C AEN VG+  A
Sbjct: 364 ISSQRLR-LSRRALRVLSMGPEDEGVYQCMAENEVGSAHA 402



 Score = 59.7 bits (138), Expect = 5e-07
 Identities = 52/190 (27%), Positives = 75/190 (39%), Gaps = 12/190 (6%)

Query: 7   TSGEAPYIIEQP--LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
           ++ EA  II  P    + V + Q   L C A G P P + W K G  V        L + 
Sbjct: 224 STAEAARIIYPPEAQTIIVTKGQSLILECVASGIPPPRVTWAKDGSSVTGYNKTRFLLSN 283

Query: 65  GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR-EEFRLEPESKQSAQGD 123
            L    +       D+G Y C A N  G   +     +V V    E  +E        G 
Sbjct: 284 LLIDTTS-----EEDSGTYRCMADNGVGQPGAAVILYNVQVFEPPEVTMELSQLVIPWGQ 338

Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
           +  L C   RG+P P+V W +N   L+     R+ L      V+    + D G YQC+A 
Sbjct: 339 SAKLTC-EVRGNPPPSVLWLRNAVPLI--SSQRLRLSRRALRVLSMGPE-DEGVYQCMAE 394

Query: 184 NAAGTRESAI 193
           N  G+  + +
Sbjct: 395 NEVGSAHAVV 404


>UniRef50_Q4SCU0 Cluster: Chromosome 7 SCAF14650, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 7 SCAF14650, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 265

 Score = 97.5 bits (232), Expect = 2e-18
 Identities = 50/109 (45%), Positives = 63/109 (57%), Gaps = 6/109 (5%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-----THRSILPAGGL 66
           P I+E P D+ V++ +PATLNC+A G P+P + WYK G  V +D     +HR +LP G L
Sbjct: 20  PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTVEWYKDGERVETDRDNPRSHRMLLPTGSL 79

Query: 67  FFLRATHG-RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP 114
           FFLR  HG R   D G Y C A N  G A S NA+L VA    +    P
Sbjct: 80  FFLRIVHGRRSKPDDGSYVCVARNYLGQAISHNASLEVATFPRQVFFSP 128



 Score = 42.7 bits (96), Expect = 0.059
 Identities = 37/127 (29%), Positives = 54/127 (42%), Gaps = 18/127 (14%)

Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGGGNMPLGRVKVLDDGSL 257
           P ++  P D++   G   T  C+  G P P V W     R     + P     +L  GSL
Sbjct: 20  PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTVEWYKDGERVETDRDNPRSHRMLLPTGSL 79

Query: 258 RLDNVI-----LADEGEYSCEAENSVG-AVSASGYL-------TVYDPPSINLSPNSVNV 304
               ++       D+G Y C A N +G A+S +  L        V+  PS+ +SP S + 
Sbjct: 80  FFLRIVHGRRSKPDDGSYVCVARNYLGQAISHNASLEVATFPRQVFFSPSVEISPYSFSQ 139

Query: 305 ES-GNVA 310
            S G VA
Sbjct: 140 TSQGYVA 146



 Score = 41.1 bits (92), Expect = 0.18
 Identities = 30/91 (32%), Positives = 46/91 (50%), Gaps = 9/91 (9%)

Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS-RMH--LVDGGNL----VIQDAR- 171
           ++G+   L C    G P P V W K+G+ +  D D+ R H  L+  G+L    ++   R 
Sbjct: 32  SKGEPATLNC-KAEGRPTPTVEWYKDGERVETDRDNPRSHRMLLPTGSLFFLRIVHGRRS 90

Query: 172 QTDAGRYQCIARNAAGTRESAIATLKIHIKP 202
           + D G Y C+ARN  G   S  A+L++   P
Sbjct: 91  KPDDGSYVCVARNYLGQAISHNASLEVATFP 121



 Score = 39.1 bits (87), Expect = 0.72
 Identities = 22/57 (38%), Positives = 27/57 (47%), Gaps = 1/57 (1%)

Query: 277 SVGAVSASGYLTVYD-PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332
           SV   S+   L   D PP I   P+ + V  G  A   C A GRP PT+ W  +G R
Sbjct: 3   SVPCYSSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTVEWYKDGER 59



 Score = 38.7 bits (86), Expect = 0.96
 Identities = 29/115 (25%), Positives = 48/115 (41%), Gaps = 10/115 (8%)

Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL------IQNHRRNVTNDG 450
           PP I   PS+  +     A   C A   P P + WY +GE +       ++HR  +    
Sbjct: 19  PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTVEWYKDGERVETDRDNPRSHRMLLPTGS 78

Query: 451 TLVLKDL----DKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVS 501
              L+ +     K D G+Y CVA +  G+ +   A L  +     + F  + ++S
Sbjct: 79  LFFLRIVHGRRSKPDDGSYVCVARNYLGQAISHNASLEVATFPRQVFFSPSVEIS 133


>UniRef50_Q967D7 Cluster: Protein turtle; n=5; Drosophila
           melanogaster|Rep: Protein turtle - Drosophila
           melanogaster (Fruit fly)
          Length = 1531

 Score = 97.5 bits (232), Expect = 2e-18
 Identities = 137/550 (24%), Positives = 212/550 (38%), Gaps = 59/550 (10%)

Query: 78  SDAGVYWCEATN-SYGTARSRNAT-LHVAV-LREEFRLEPESKQSAQ-GDTVVLECLPPR 133
           SD G Y C+    +    + +N T  H+ V     F + PE       GD+++L C    
Sbjct: 220 SDQGWYECKVVFLNRDPKQHKNGTWFHLDVHAPPRFSVTPEDIIYVNLGDSIILNCQAD- 278

Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
           G+P P + W K+   +  D    + +  DG  L I   R  D G Y CIARN  G + S 
Sbjct: 279 GTPTPEILWYKDANPV--DPSPTVGIFNDGTELRISTIRHEDIGEYTCIARNGEG-QVSH 335

Query: 193 IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP-LPDVLWRRSAGGGNMPLG---R 248
            A + I     ++  P +     G  V F C     P    V W R             R
Sbjct: 336 TARVIIAGGAVIMVPPTNQTKLEGEKVIFSCEAKAMPGNVTVRWYREGSPVREVAALETR 395

Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSPNSVNVESG 307
           V +  DGSL ++ +   D G+Y CE  N +G   SAS YL+V  P  +  +P    +   
Sbjct: 396 VTIRKDGSLIINPIKPDDSGQYLCEVTNGIGDPQSASAYLSVEYPAKVTFTPTVQYLPFR 455

Query: 308 NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT-INDTDKNDS 366
                 C     P+   + +   ++ ++ P   +D      + +G  + T +N+    + 
Sbjct: 456 LAGVVQCYIKSSPQ-LQYVTWTKDKRLLEPYQMKD---IVVMANGSLLFTRVNE----EH 507

Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN-QTLPIKSMAVFPCTAI--- 422
           +    C+  N  G++   G + V     R PP  T  P       +       C A+   
Sbjct: 508 QGQYACTPYNAQGTAGASGVMDVLV---RKPPAFTVEPETLYQRKVGDSVEMHCDALEAE 564

Query: 423 CTPEPIIAWYF-EGEALIQNHRRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
            T  P I W   EGE L ++ R  +  + G + +++L + D G Y CV S+     +   
Sbjct: 565 GTERPTIKWQRQEGEQLTESQRNRIKISGGNITIENLRREDFGYYQCVVSNEVATLMAVT 624

Query: 481 ALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQV 540
            L+++                + P  P   IT   T++S+TL W      GS     Y  
Sbjct: 625 QLVIE---------------GTQPHAPYN-ITGKATESSITLQWLPGYSGGSEYKQDY-- 666

Query: 541 EVFSRETLSGNNTPRNSRGWVVIA-RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
            ++ RE  +G N       W  I+      T   +  L  G TY F V   N  G    S
Sbjct: 667 TIWFRE--AGVN------DWQTISVTPSGSTQVTINGLASGTTYEFQVVGRNVLGDGMMS 718

Query: 600 PVSDSVTVGD 609
            V    T+ D
Sbjct: 719 KVMTVRTLED 728



 Score = 89.0 bits (211), Expect = 7e-16
 Identities = 81/330 (24%), Positives = 138/330 (41%), Gaps = 23/330 (6%)

Query: 164 NLVIQDARQTDAGRYQC----IARNAAGTRESAIATLKIHIKPYLITGPEDVV-AQTGSS 218
           +L + + R++D G Y+C    + R+    +      L +H  P     PED++    G S
Sbjct: 211 SLNLTNIRESDQGWYECKVVFLNRDPKQHKNGTWFHLDVHAPPRFSVTPEDIIYVNLGDS 270

Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENS 277
           +   C+  G P P++LW + A   + P   V + +DG+ LR+  +   D GEY+C A N 
Sbjct: 271 IILNCQADGTPTPEILWYKDANPVD-PSPTVGIFNDGTELRISTIRHEDIGEYTCIARNG 329

Query: 278 VGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP-EPTMFWSVEGNRTIIF 336
            G VS +  + +     I + P +     G    F+C A   P   T+ W  EG+     
Sbjct: 330 EGQVSHTARVIIAGGAVIMVPPTNQTKLEGEKVIFSCEAKAMPGNVTVRWYREGSPVREV 389

Query: 337 PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGS-SFVRGKLTVTSDDDR 395
             +   +   T   DG   L IN    +DS    +C   N  G        L+V      
Sbjct: 390 AAL---ETRVTIRKDG--SLIINPIKPDDS-GQYLCEVTNGIGDPQSASAYLSV-----E 438

Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN---VTNDGTL 452
            P  +T  P+ Q LP +   V  C    +P+     + + + L++ ++     V  +G+L
Sbjct: 439 YPAKVTFTPTVQYLPFRLAGVVQCYIKSSPQLQYVTWTKDKRLLEPYQMKDIVVMANGSL 498

Query: 453 VLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482
           +   +++   G Y C   +  G    SG +
Sbjct: 499 LFTRVNEEHQGQYACTPYNAQGTAGASGVM 528



 Score = 88.2 bits (209), Expect = 1e-15
 Identities = 80/306 (26%), Positives = 126/306 (41%), Gaps = 15/306 (4%)

Query: 31  LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
           LNC+A G+P+P I WYK    V       I   G    LR +  R H D G Y C A N 
Sbjct: 273 LNCQADGTPTPEILWYKDANPVDPSPTVGIFNDG--TELRISTIR-HEDIGEYTCIARNG 329

Query: 91  YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL- 149
            G   S  A + +A       + P ++   +G+ V+  C          V W + G  + 
Sbjct: 330 EGQV-SHTARVIIAG-GAVIMVPPTNQTKLEGEKVIFSCEAKAMPGNVTVRWYREGSPVR 387

Query: 150 -LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208
            +   ++R+ +   G+L+I   +  D+G+Y C   N  G  +SA A L +     +   P
Sbjct: 388 EVAALETRVTIRKDGSLIINPIKPDDSGQYLCEVTNGIGDPQSASAYLSVEYPAKVTFTP 447

Query: 209 EDVVAQTGSSVTFQCRVGGDP-LPDVLWRRSAG-GGNMPLGRVKVLDDGSLRLDNVILAD 266
                    +   QC +   P L  V W +         +  + V+ +GSL    V    
Sbjct: 448 TVQYLPFRLAGVVQCYIKSSPQLQYVTWTKDKRLLEPYQMKDIVVMANGSLLFTRVNEEH 507

Query: 267 EGEYSCEAENSVGAVSASGYLTVY--DPPSINLSPNSV-NVESGNVARFTC---TATGRP 320
           +G+Y+C   N+ G   ASG + V    PP+  + P ++   + G+     C    A G  
Sbjct: 508 QGQYACTPYNAQGTAGASGVMDVLVRKPPAFTVEPETLYQRKVGDSVEMHCDALEAEGTE 567

Query: 321 EPTMFW 326
            PT+ W
Sbjct: 568 RPTIKW 573



 Score = 65.3 bits (152), Expect = 1e-08
 Identities = 67/256 (26%), Positives = 102/256 (39%), Gaps = 24/256 (9%)

Query: 60  ILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESK- 117
           ++  G L F R          G Y C   N+ GTA + +  + V V +   F +EPE+  
Sbjct: 492 VMANGSLLFTRVNE----EHQGQYACTPYNAQGTAGA-SGVMDVLVRKPPAFTVEPETLY 546

Query: 118 QSAQGDTVVLEC--LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175
           Q   GD+V + C  L   G+  P + W++     L +       + GGN+ I++ R+ D 
Sbjct: 547 QRKVGDSVEMHCDALEAEGTERPTIKWQRQEGEQLTESQRNRIKISGGNITIENLRREDF 606

Query: 176 GRYQCIARNAAGTRESAIATLKIH----IKPYLITGPEDVVAQTGSSVTFQC---RVGGD 228
           G YQC+  N   T   A+  L I       PY ITG       T SS+T Q      GG 
Sbjct: 607 GYYQCVVSNEVATL-MAVTQLVIEGTQPHAPYNITG-----KATESSITLQWLPGYSGGS 660

Query: 229 PLPD--VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY 286
                  +W R AG  +     V       + ++ +      E+     N +G    S  
Sbjct: 661 EYKQDYTIWFREAGVNDWQTISVTPSGSTQVTINGLASGTTYEFQVVGRNVLGDGMMSKV 720

Query: 287 LTVYDPPSINLSPNSV 302
           +TV        +P +V
Sbjct: 721 MTVRTLEDAPAAPRNV 736


>UniRef50_A7RNL2 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 267

 Score = 97.1 bits (231), Expect = 3e-18
 Identities = 75/261 (28%), Positives = 116/261 (44%), Gaps = 20/261 (7%)

Query: 31  LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
           L C   G P P I   K GV ++            +    A H      AG Y C+AT++
Sbjct: 19  LECIVYGMPVPKITLRKKGVHMILGQVTGNARRHYIPKFTANH------AGKYKCKATDT 72

Query: 91  YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
            G   +    + +   + E+   P+   +       L C    G+P     W  NGQ L+
Sbjct: 73  SGRTDTSTTIVRMEA-KPEWITRPQDTIAGVNSNTTLRC-HASGAPRVFYQWYCNGQPLV 130

Query: 151 FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE- 209
               S+ H++  G+L++++ R +D G YQC+  N  G     IA+ ++ +       PE 
Sbjct: 131 ---TSQRHILHQGDLILKELRYSDGGMYQCVVTNTHG---QLIASAELTVAG--TRAPEA 182

Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNVILADEG 268
              A   S+VT  C+  G+P P V WR+  G   +  G R + L  G L++ NV   D G
Sbjct: 183 SKNALVDSTVTLHCQPSGNPKPMVRWRK--GSVYLSSGPRYQFLTSGDLKISNVTSLDSG 240

Query: 269 EYSCEAENSVGAVSASGYLTV 289
            Y+CE  N +G+ S +G L V
Sbjct: 241 RYTCEVSNRLGSASRTGRLNV 261



 Score = 85.0 bits (201), Expect = 1e-14
 Identities = 59/214 (27%), Positives = 100/214 (46%), Gaps = 16/214 (7%)

Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFD---GDSRMHLVDGGNLVIQDARQ 172
           +K + +G+  VLEC+   G P P +  +K G  ++     G++R H        I     
Sbjct: 8   TKIALKGERFVLECIV-YGMPVPKITLRKKGVHMILGQVTGNARRHY-------IPKFTA 59

Query: 173 TDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
             AG+Y+C A + +G  +++   +++  KP  IT P+D +A   S+ T +C   G   P 
Sbjct: 60  NHAGKYKCKATDTSGRTDTSTTIVRMEAKPEWITRPQDTIAGVNSNTTLRCHASG--APR 117

Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
           V ++    G  +   +  +L  G L L  +  +D G Y C   N+ G + AS  LTV   
Sbjct: 118 VFYQWYCNGQPLVTSQRHILHQGDLILKELRYSDGGMYQCVVTNTHGQLIASAELTVAGT 177

Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326
            +   S N++ V+S       C  +G P+P + W
Sbjct: 178 RAPEASKNAL-VDS--TVTLHCQPSGNPKPMVRW 208



 Score = 82.2 bits (194), Expect = 8e-14
 Identities = 61/178 (34%), Positives = 85/178 (47%), Gaps = 15/178 (8%)

Query: 12  PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
           P  I +P D     +   TL C A G+P    +WY  G  +V+ + R IL  G L     
Sbjct: 89  PEWITRPQDTIAGVNSNTTLRCHASGAPRVFYQWYCNGQPLVT-SQRHILHQGDLILKEL 147

Query: 72  THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD-TVVLECL 130
                +SD G+Y C  TN++G   + +A L VA  R      PE+ ++A  D TV L C 
Sbjct: 148 R----YSDGGMYQCVVTNTHGQLIA-SAELTVAGTR-----APEASKNALVDSTVTLHC- 196

Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
            P G+P+P V W+K G   L  G  R   +  G+L I +    D+GRY C   N  G+
Sbjct: 197 QPSGNPKPMVRWRK-GSVYLSSG-PRYQFLTSGDLKISNVTSLDSGRYTCEVSNRLGS 252



 Score = 55.2 bits (127), Expect = 1e-05
 Identities = 29/88 (32%), Positives = 44/88 (50%), Gaps = 2/88 (2%)

Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKD 456
           P  IT  P +    + S     C A   P     WY  G+ L+ + +R++ + G L+LK+
Sbjct: 89  PEWITR-PQDTIAGVNSNTTLRCHASGAPRVFYQWYCNGQPLVTS-QRHILHQGDLILKE 146

Query: 457 LDKSDSGTYTCVASSRHGKYVWSGALLV 484
           L  SD G Y CV ++ HG+ + S  L V
Sbjct: 147 LRYSDGGMYQCVVTNTHGQLIASAELTV 174



 Score = 49.6 bits (113), Expect = 5e-04
 Identities = 28/74 (37%), Positives = 38/74 (51%), Gaps = 5/74 (6%)

Query: 30  TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
           TL+C+  G+P P +RW KG V + S      L +G L     T      D+G Y CE +N
Sbjct: 193 TLHCQPSGNPKPMVRWRKGSVYLSSGPRYQFLTSGDLKISNVT----SLDSGRYTCEVSN 248

Query: 90  SYGTARSRNATLHV 103
             G+A SR   L+V
Sbjct: 249 RLGSA-SRTGRLNV 261



 Score = 48.4 bits (110), Expect = 0.001
 Identities = 63/277 (22%), Positives = 97/277 (35%), Gaps = 29/277 (10%)

Query: 212 VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLR---LDNVILADEG 268
           +A  G     +C V G P+P +  R+   G +M LG+V     G+ R   +        G
Sbjct: 10  IALKGERFVLECIVYGMPVPKITLRKK--GVHMILGQVT----GNARRHYIPKFTANHAG 63

Query: 269 EYSCEAENSVGAVSASGYLTVYDP-PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327
           +Y C+A ++ G    S  +   +  P     P        +     C A+G P     W 
Sbjct: 64  KYKCKATDTSGRTDTSTTIVRMEAKPEWITRPQDTIAGVNSNTTLRCHASGAPRVFYQWY 123

Query: 328 VEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387
             G   +        + H     D    L + +   +D      C   N  G      +L
Sbjct: 124 CNGQPLVT------SQRHILHQGD----LILKELRYSDG-GMYQCVVTNTHGQLIASAEL 172

Query: 388 TVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT 447
           TV     R P    N   + T+ +       C     P+P++ W      L    R    
Sbjct: 173 TVAGT--RAPEASKNALVDSTVTLH------CQPSGNPKPMVRWRKGSVYLSSGPRYQFL 224

Query: 448 NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
             G L + ++   DSG YTC  S+R G    +G L V
Sbjct: 225 TSGDLKISNVTSLDSGRYTCEVSNRLGSASRTGRLNV 261


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.315    0.132    0.393 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 1,441,545,397
Number of Sequences: 1657284
Number of extensions: 65956432
Number of successful extensions: 195383
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 710
Number of HSP's successfully gapped in prelim test: 928
Number of HSP's that attempted gapping in prelim test: 166959
Number of HSP's gapped (non-prelim): 15182
length of query: 1207
length of database: 575,637,011
effective HSP length: 109
effective length of query: 1098
effective length of database: 394,993,055
effective search space: 433702374390
effective search space used: 433702374390
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 78 (35.5 bits)

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